# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- rve PF00665.21 CEP06770.1 - 9.7e-16 57.9 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP06770.1 - 0.0069 15.7 0.8 0.014 14.8 0.6 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF3507 PF12015.3 CEP06770.1 - 0.14 11.6 1.5 13 5.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3507) Retrotrans_gag PF03732.12 CEP06771.1 - 0.00017 21.5 0.1 0.00037 20.4 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4129 PF13559.1 CEP06771.1 - 0.033 14.1 0.5 0.07 13.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Oxysterol_BP PF01237.13 CEP06773.1 - 4.3e-82 275.4 0.0 5e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein CPL PF08144.6 CEP06774.1 - 1.3e-34 119.1 4.0 5.5e-34 117.1 0.3 3.3 4 0 0 4 4 4 1 CPL (NUC119) domain PUF PF00806.14 CEP06774.1 - 2.1e-07 30.0 1.9 4.2 7.0 0.0 6.6 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat TraH PF06122.6 CEP06774.1 - 0.041 12.7 0.6 0.11 11.2 0.4 1.7 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Bestrophin PF01062.16 CEP06774.1 - 0.13 11.2 0.5 8.4 5.2 0.0 2.3 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF1744 PF08490.7 CEP06775.1 - 1.5e-119 399.1 0.4 2.3e-119 398.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CEP06775.1 - 1.3e-64 218.1 3.1 1.3e-64 218.1 2.1 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CEP06775.1 - 1.6e-20 73.3 0.1 7.9e-18 64.4 0.0 3.6 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CEP06775.1 - 2.9e-10 40.0 0.2 9e-10 38.4 0.1 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CEP06775.1 - 4e-06 26.7 1.7 1.3e-05 25.0 0.0 2.8 4 0 0 4 4 4 1 RNase_H superfamily Cytochrom_c3_2 PF14537.1 CEP06775.1 - 0.12 12.6 7.0 0.4 11.0 4.9 1.9 1 0 0 1 1 1 0 Cytochrome c3 FYDLN_acid PF09538.5 CEP06776.1 - 3.3 8.3 20.8 3.9 8.1 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4637 PF15470.1 CEP06776.1 - 4.2 6.9 10.2 4.9 6.7 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF1510 PF07423.6 CEP06776.1 - 5.1 6.3 10.2 5.8 6.2 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mpp10 PF04006.7 CEP06776.1 - 9.1 4.5 18.0 9.2 4.4 12.5 1.0 1 0 0 1 1 1 0 Mpp10 protein RVT_1 PF00078.22 CEP06777.1 - 6.5e-24 84.4 0.0 2.3e-23 82.6 0.0 2.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP06777.1 - 7.1e-22 77.7 0.0 2e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 CEP06777.1 - 4.4e-13 49.1 0.0 1.4e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.6 CEP06777.1 - 1.4e-05 25.0 0.1 0.00051 19.9 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.15 CEP06777.1 - 3.4e-05 23.6 1.4 6.2e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEP06777.1 - 0.00078 19.8 0.0 0.0028 18.1 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP06777.1 - 0.02 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 CEP06777.1 - 4 7.5 6.5 1.4 8.9 0.8 2.4 2 0 0 2 2 2 0 Zinc knuckle PIF1 PF05970.9 CEP06778.1 - 3.4e-07 29.5 0.2 4.6e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 CEP06778.1 - 1.5e-05 25.0 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEP06778.1 - 0.00037 18.3 0.0 0.00051 17.9 0.0 1.2 1 0 0 1 1 1 1 Helicase DUF2824 PF11039.3 CEP06778.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) Chromo PF00385.19 CEP06779.1 - 2.3e-09 36.7 0.2 3.7e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HAD_2 PF13419.1 CEP06784.1 - 4.7e-07 30.1 0.1 1.1e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Transposase_22 PF02994.9 CEP06785.1 - 0.045 12.2 0.1 0.091 11.2 0.1 1.5 1 1 0 1 1 1 0 L1 transposable element DUF4152 PF13680.1 CEP06785.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4152) PLDc PF00614.17 CEP06786.1 - 8.6e-18 63.5 2.8 6.3e-11 41.7 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CEP06786.1 - 5.3e-13 48.8 0.8 1.1e-05 25.1 0.1 3.6 3 0 0 3 3 3 3 PLD-like domain PX PF00787.19 CEP06786.1 - 2e-05 24.3 0.0 7.2e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 PX domain ArfGap PF01412.13 CEP06787.1 - 6.5e-39 132.3 0.1 6.5e-39 132.3 0.0 3.1 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf UBA PF00627.26 CEP06787.1 - 1.8e-10 40.3 0.1 0.00037 20.2 0.0 2.8 3 0 0 3 3 3 2 UBA/TS-N domain Exo_endo_phos PF03372.18 CEP06789.1 - 3.3e-09 37.0 0.5 3.3e-09 37.0 0.3 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CEP06789.1 - 5.5e-07 29.1 0.1 1.6e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP06789.1 - 2.9e-05 23.6 0.1 2.9e-05 23.6 0.1 2.4 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 CEP06790.1 - 7.2e-07 28.8 1.0 1.2e-06 28.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEP06790.1 - 6.2e-06 26.1 0.8 1.5e-05 24.9 0.6 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 CEP06790.1 - 6.9e-06 25.8 0.1 1.9e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CEP06790.1 - 1.9e-05 25.0 0.0 5.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease BPS PF08947.5 CEP06790.1 - 0.087 12.4 0.0 0.27 10.8 0.0 1.9 1 0 0 1 1 1 0 BPS (Between PH and SH2) zf-CCHC_4 PF14392.1 CEP06790.1 - 0.15 11.7 0.5 0.38 10.4 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Chromo PF00385.19 CEP06791.1 - 3.5e-07 29.7 0.1 9.4e-07 28.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NPV_P10 PF05531.7 CEP06791.1 - 0.067 13.4 0.4 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tudor-knot PF11717.3 CEP06791.1 - 0.12 12.0 1.0 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain RVT_1 PF00078.22 CEP06792.1 - 7.8e-32 110.3 0.2 4.7e-31 107.8 0.0 2.1 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP06793.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RNase_H_2 PF13482.1 CEP06793.1 - 0.064 13.0 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 RNase_H superfamily rve_3 PF13683.1 CEP06793.1 - 0.095 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain PIF1 PF05970.9 CEP06794.1 - 5.2e-59 200.0 0.0 5.9e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA PF00004.24 CEP06795.1 - 2.1e-05 24.7 0.1 0.00018 21.7 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP06795.1 - 0.0073 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP06795.1 - 0.029 14.3 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 CEP06795.1 - 0.031 13.4 0.1 0.076 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 CEP06795.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Transposase_21 PF02992.9 CEP06796.1 - 3.3e-08 32.8 0.3 4.8e-08 32.3 0.0 1.4 2 0 0 2 2 2 1 Transposase family tnp2 zf-RVT PF13966.1 CEP06799.1 - 0.00046 20.4 0.7 0.0014 18.9 0.5 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FragX_IP PF05994.6 CEP06800.1 - 0.047 11.4 0.1 0.079 10.7 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family DUF4446 PF14584.1 CEP06800.1 - 0.37 10.5 1.9 0.73 9.6 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Ribosomal_L18_c PF14204.1 CEP06801.1 - 8.9e-29 99.9 2.7 1.2e-28 99.4 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.17 CEP06801.1 - 9.9e-28 96.7 0.0 1.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L18p/L5e family DDE_3 PF13358.1 CEP06802.1 - 1.4e-21 76.7 0.0 1.7e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP06802.1 - 9.3e-05 21.6 0.1 0.00012 21.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 CEP06802.1 - 0.065 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain UPF0560 PF10577.4 CEP06803.1 - 0.15 10.2 7.9 0.19 9.9 5.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 OATP PF03137.15 CEP06803.1 - 0.94 7.4 3.1 1.3 6.9 2.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4175 PF13779.1 CEP06803.1 - 1.2 6.7 22.1 1.9 6.0 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CEP06803.1 - 2 6.5 28.7 2.6 6.1 19.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CEP06803.1 - 2.4 6.8 19.6 3.8 6.2 13.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SprA-related PF12118.3 CEP06803.1 - 5.3 6.2 19.7 7.7 5.7 13.7 1.1 1 0 0 1 1 1 0 SprA-related family OmpH PF03938.9 CEP06803.1 - 7.1 6.5 21.7 11 5.8 15.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PIF1 PF05970.9 CEP06805.1 - 8.6e-27 94.0 3.4 2.1e-08 33.5 0.0 3.3 1 1 2 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 CEP06805.1 - 9e-10 38.4 0.0 1.8e-08 34.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain DAP3 PF10236.4 CEP06805.1 - 0.0007 18.6 0.0 0.42 9.4 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 Herpes_Helicase PF02689.9 CEP06805.1 - 0.0019 16.0 0.1 0.54 7.9 0.0 2.1 2 0 0 2 2 2 2 Helicase DUF2791 PF10923.3 CEP06805.1 - 0.0031 16.1 0.0 0.0053 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.13 CEP06805.1 - 0.0081 15.7 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 CEP06805.1 - 0.029 14.3 0.0 0.14 12.1 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 CEP06805.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AFG1_ATPase PF03969.11 CEP06805.1 - 0.032 13.0 0.0 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase KAP_NTPase PF07693.9 CEP06805.1 - 0.075 12.0 0.0 0.5 9.3 0.0 2.1 2 1 0 3 3 3 0 KAP family P-loop domain AAA_22 PF13401.1 CEP06805.1 - 0.088 12.9 0.0 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DNA_pol_A_exo1 PF01612.15 CEP06806.1 - 1.6e-17 63.5 0.0 2.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF1836 PF08876.6 CEP06810.1 - 0.077 12.7 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) EF-hand_8 PF13833.1 CEP06811.1 - 0.00086 18.8 2.2 0.016 14.8 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 CEP06811.1 - 0.0034 16.6 0.0 0.011 15.1 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CEP06811.1 - 0.0066 16.5 5.7 0.39 10.8 0.1 4.2 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 CEP06811.1 - 0.13 11.6 0.1 0.13 11.6 0.0 3.3 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.1 CEP06811.1 - 0.64 10.0 0.1 0.64 10.0 0.0 3.7 4 1 1 5 5 5 0 EF-hand domain UCH PF00443.24 CEP06812.1 - 3e-58 197.0 0.3 4.6e-58 196.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CEP06812.1 - 2.9e-57 193.7 2.3 5.2e-56 189.6 0.4 2.9 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 CEP06812.1 - 1.6e-51 174.8 1.1 1.6e-51 174.8 0.7 3.3 3 1 1 4 4 4 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 CEP06812.1 - 4.2e-30 105.2 0.0 7.3e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CEP06812.1 - 8.4e-13 48.6 0.2 2.9e-12 46.8 0.1 2.0 1 0 0 1 1 1 1 MATH domain YukD PF08817.5 CEP06812.1 - 0.019 15.4 0.1 4.3 7.9 0.1 2.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD NeA_P2 PF12312.3 CEP06812.1 - 0.21 10.8 1.2 0.55 9.4 0.9 1.6 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein FUN14 PF04930.10 CEP06813.1 - 0.013 15.7 0.4 0.023 14.9 0.1 1.5 1 1 0 1 1 1 0 FUN14 family Lipoprotein_6 PF01441.14 CEP06813.1 - 0.014 15.2 1.7 0.017 14.9 1.2 1.1 1 0 0 1 1 1 0 Lipoprotein P4Ha_N PF08336.6 CEP06813.1 - 0.02 14.7 1.7 0.025 14.4 1.2 1.0 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spectrin PF00435.16 CEP06813.1 - 0.022 15.0 0.8 0.028 14.6 0.5 1.2 1 0 0 1 1 1 0 Spectrin repeat DegS PF05384.6 CEP06813.1 - 0.03 13.5 0.7 0.037 13.2 0.5 1.1 1 0 0 1 1 1 0 Sensor protein DegS GrpE PF01025.14 CEP06813.1 - 0.04 13.4 2.0 0.047 13.2 1.4 1.1 1 0 0 1 1 1 0 GrpE SGIII PF15467.1 CEP06813.1 - 0.041 12.9 1.0 0.041 12.9 0.7 1.0 1 0 0 1 1 1 0 Secretogranin-3 Apolipoprotein PF01442.13 CEP06813.1 - 0.057 12.9 1.7 0.065 12.7 1.2 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CENP-H PF05837.7 CEP06813.1 - 0.061 13.5 1.0 0.086 13.0 0.7 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4586 PF15239.1 CEP06813.1 - 0.08 12.4 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) Myb_DNA-bind_5 PF13873.1 CEP06813.1 - 0.11 12.3 1.0 0.14 12.0 0.7 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain K-box PF01486.12 CEP06813.1 - 0.14 11.9 2.1 0.18 11.6 1.5 1.1 1 0 0 1 1 1 0 K-box region GreA_GreB_N PF03449.10 CEP06813.1 - 0.16 12.0 1.9 0.22 11.5 1.0 1.4 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal 4HB_MCP_1 PF12729.2 CEP06813.1 - 0.19 11.0 2.8 0.22 10.8 1.9 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Prefoldin_2 PF01920.15 CEP06813.1 - 0.29 10.9 4.4 0.34 10.6 3.1 1.1 1 0 0 1 1 1 0 Prefoldin subunit AIF-MLS PF14962.1 CEP06813.1 - 0.33 10.5 1.9 0.46 10.1 1.3 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF4163 PF13739.1 CEP06813.1 - 1.1 10.1 4.6 1.1 10.0 3.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4163) DUF883 PF05957.8 CEP06813.1 - 4 7.9 6.9 0.15 12.4 0.8 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ORMDL PF04061.9 CEP06814.1 - 2.9e-47 159.6 3.4 3.8e-47 159.2 2.4 1.1 1 0 0 1 1 1 1 ORMDL family Cyclin PF08613.6 CEP06815.1 - 6.1e-15 55.9 0.3 6.1e-15 55.9 0.2 1.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CEP06815.1 - 0.0067 15.9 2.9 0.0099 15.4 0.4 2.4 1 1 0 2 2 2 1 Cyclin, N-terminal domain Tom37_C PF11801.3 CEP06815.1 - 0.084 12.7 4.1 0.051 13.4 0.9 2.0 2 1 0 2 2 2 0 Tom37 C-terminal domain Fcf2 PF08698.6 CEP06815.1 - 0.12 12.4 1.1 0.55 10.2 0.3 2.2 2 0 0 2 2 2 0 Fcf2 pre-rRNA processing Zn_clus PF00172.13 CEP06817.1 - 4.3e-09 36.1 9.1 9e-09 35.1 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 CEP06818.1 - 9e-37 126.6 0.1 2.8e-36 125.0 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.13 CEP06819.1 - 7.2e-09 35.5 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 CEP06821.1 - 5.4e-32 110.5 0.0 9.8e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP06821.1 - 9.6e-05 22.4 0.0 0.0003 20.9 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP06821.1 - 0.00046 20.1 0.6 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP06821.1 - 0.0036 17.5 0.1 2.3 8.5 0.0 3.6 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.21 CEP06821.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DDE_1 PF03184.14 CEP06821.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Abhydrolase_6 PF12697.2 CEP06822.1 - 8e-25 88.0 0.1 1.1e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP06822.1 - 1.4e-17 64.0 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP06822.1 - 5.3e-12 45.7 0.0 1.7e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CEP06822.1 - 0.00023 20.6 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 CEP06822.1 - 0.00082 19.1 0.1 0.0022 17.7 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Thioesterase PF00975.15 CEP06822.1 - 0.014 15.6 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 CEP06822.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PPR_2 PF13041.1 CEP06823.1 - 4.5e-13 48.9 3.5 2e-09 37.2 0.1 3.5 2 1 2 4 4 4 2 PPR repeat family PPR_3 PF13812.1 CEP06823.1 - 7.2e-10 38.3 2.1 0.00036 20.5 0.1 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 CEP06823.1 - 1.5e-08 34.0 0.9 0.0056 16.5 0.0 3.9 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 CEP06823.1 - 0.00027 20.3 0.0 0.0085 15.5 0.0 2.9 2 1 0 2 2 2 1 PPR repeat TPR_19 PF14559.1 CEP06823.1 - 0.0037 17.5 1.6 0.78 10.1 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2989 PF11207.3 CEP06823.1 - 0.019 14.4 6.8 1.2 8.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2989) RNA_pol_Rpb5_C PF01191.14 CEP06824.1 - 8.6e-37 124.5 0.8 1.7e-36 123.6 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CEP06824.1 - 7.9e-29 99.9 0.0 1.5e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CEP06824.1 - 0.042 13.6 0.0 0.22 11.3 0.0 2.0 1 1 1 2 2 2 0 Restriction endonuclease Phosphodiest PF01663.17 CEP06825.1 - 9.8e-11 41.5 0.2 2e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CEP06825.1 - 0.0028 16.8 0.1 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CEP06825.1 - 0.01 15.2 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily MBOAT_2 PF13813.1 CEP06826.1 - 1.4e-08 34.6 1.2 4.6e-08 33.0 0.8 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ALMT PF11744.3 CEP06827.1 - 0.013 14.1 1.8 0.021 13.4 1.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Thioredoxin_8 PF13905.1 CEP06827.1 - 0.74 9.9 6.3 0.89 9.7 0.2 3.8 5 0 0 5 5 5 0 Thioredoxin-like NAD_binding_6 PF08030.7 CEP06828.1 - 2e-16 60.2 0.0 7.1e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CEP06828.1 - 4.6e-15 55.3 0.0 9.1e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CEP06828.1 - 2.2e-11 43.9 6.5 6.6e-11 42.3 4.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 CEP06828.1 - 0.00017 21.6 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Mating_C PF12737.2 CEP06829.1 - 0.0072 15.2 1.0 0.0089 14.9 0.7 1.0 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 Alpha_GJ PF03229.8 CEP06829.1 - 9.7 6.5 13.3 3.2 8.1 2.5 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J Sec23_trunk PF04811.10 CEP06830.1 - 3.6e-78 262.2 0.0 5.2e-78 261.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CEP06830.1 - 5.4e-33 112.5 0.1 1.2e-32 111.4 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CEP06830.1 - 2.8e-31 107.8 0.4 5.3e-31 106.9 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CEP06830.1 - 1.1e-17 63.2 5.1 2.3e-17 62.2 3.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CEP06830.1 - 2.8e-14 52.5 0.0 8.1e-14 51.0 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat HEV_ORF1 PF02444.11 CEP06831.1 - 0.0041 17.2 0.1 0.0068 16.5 0.1 1.3 1 0 0 1 1 1 1 Hepatitis E virus ORF-2 (Putative capsid protein) Pkinase PF00069.20 CEP06832.1 - 2.6e-56 190.6 0.0 4.8e-56 189.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP06832.1 - 3.9e-21 75.2 0.0 7.8e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP06832.1 - 3e-06 26.3 0.0 5.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 CEP06832.1 - 1.6e-05 25.1 0.0 0.013 15.8 0.0 3.7 3 1 0 3 3 3 1 PAS domain Kdo PF06293.9 CEP06832.1 - 0.00051 19.1 0.0 0.00092 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myc_N PF01056.13 CEP06832.1 - 0.0044 16.2 0.7 0.0044 16.2 0.5 2.0 2 0 0 2 2 2 1 Myc amino-terminal region APH PF01636.18 CEP06832.1 - 0.017 14.8 0.8 0.11 12.2 0.3 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.6 CEP06832.1 - 0.057 12.6 0.4 0.37 9.9 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Caps_synth PF05704.7 CEP06834.1 - 0.035 13.2 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DDE_3 PF13358.1 CEP06835.1 - 1.4e-34 118.9 0.0 2.9e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP06835.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease rve PF00665.21 CEP06835.1 - 0.038 14.0 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.18 CEP06837.1 - 0.0051 16.6 4.1 0.0051 16.6 2.9 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CEP06837.1 - 0.017 14.8 4.7 0.67 9.6 1.5 2.3 2 0 0 2 2 2 0 Zinc knuckle Na_trans_assoc PF06512.8 CEP06837.1 - 0.023 14.6 5.4 0.032 14.1 3.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated zf-CHY PF05495.7 CEP06837.1 - 0.03 14.4 5.4 0.065 13.3 3.8 1.6 1 0 0 1 1 1 0 CHY zinc finger DUF2920 PF11144.3 CEP06838.1 - 0.066 12.2 0.2 0.074 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) CBFB_NFYA PF02045.10 CEP06840.1 - 1.4e-30 105.5 5.5 3.4e-30 104.3 3.8 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Pex14_N PF04695.8 CEP06840.1 - 0.68 9.9 15.5 0.13 12.3 3.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RA PF00788.18 CEP06841.1 - 2.2e-07 31.2 0.0 2.2e-07 31.2 0.0 2.8 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain EIIBC-GUT_N PF03612.9 CEP06841.1 - 0.75 9.3 6.5 1.9 8.1 4.5 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus BAF1_ABF1 PF04684.8 CEP06841.1 - 9.7 4.9 27.7 21 3.8 19.2 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DDT PF02791.12 CEP06842.1 - 0.077 12.7 0.0 8.4 6.2 0.0 2.1 2 0 0 2 2 2 0 DDT domain B3_4 PF03483.12 CEP06843.1 - 0.083 12.3 0.1 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 B3/4 domain Fib_alpha PF08702.5 CEP06845.1 - 0.22 11.6 3.0 0.41 10.7 2.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LINES_C PF14695.1 CEP06847.1 - 5.5e-05 22.3 1.0 0.00011 21.3 0.2 1.8 2 0 0 2 2 2 1 Lines C-terminus F-box PF00646.28 CEP06848.1 - 0.0018 17.8 0.8 0.0018 17.8 0.6 2.0 2 0 0 2 2 2 1 F-box domain Asp_protease PF09668.5 CEP06850.1 - 1.2e-09 37.7 0.0 2.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CEP06850.1 - 2.8e-07 30.9 0.0 6.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP06850.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP06850.1 - 0.0028 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CEP06850.1 - 0.0084 16.0 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Cwf_Cwc_15 PF04889.7 CEP06850.1 - 0.029 14.0 8.4 0.048 13.3 5.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 CEP06850.1 - 0.89 8.7 6.5 1.6 7.9 4.5 1.3 1 0 0 1 1 1 0 NOA36 protein Pyr_redox_2 PF07992.9 CEP06851.1 - 1.2e-12 48.0 1.4 2e-10 40.8 1.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP06851.1 - 4.2e-07 30.2 0.6 0.14 12.2 0.0 3.2 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP06851.1 - 7.5e-05 22.5 0.3 0.39 10.4 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 CEP06851.1 - 0.0018 16.8 0.0 0.012 14.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 CEP06851.1 - 0.0026 18.1 0.3 0.14 12.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEP06851.1 - 0.0028 16.7 0.0 0.41 9.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 CEP06851.1 - 0.0028 16.6 0.1 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CEP06851.1 - 0.0097 14.8 0.1 0.45 9.3 0.0 2.2 1 1 1 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CEP06851.1 - 0.025 13.4 0.0 0.052 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Attachment_P66 PF11263.3 CEP06851.1 - 0.044 12.7 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 Thi4 PF01946.12 CEP06851.1 - 0.05 12.6 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 CEP06851.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain C2 PF00168.25 CEP06852.1 - 3.1e-17 62.1 4.5 6.5e-08 32.3 0.5 3.1 3 0 0 3 3 3 2 C2 domain 4HBT PF03061.17 CEP06853.1 - 0.0078 16.3 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily RVT_1 PF00078.22 CEP06855.1 - 8.2e-09 35.1 1.6 3.3e-08 33.1 1.1 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4286 PF14114.1 CEP06855.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) RVP PF00077.15 CEP06855.1 - 0.066 13.1 0.2 0.4 10.6 0.1 2.4 2 1 0 2 2 2 0 Retroviral aspartyl protease rve PF00665.21 CEP06856.1 - 6.6e-18 64.9 0.0 3.5e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CEP06857.1 - 1.4e-20 73.6 0.0 1.9e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP06857.1 - 2.6e-07 31.0 0.0 5.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP06857.1 - 3.9e-07 29.7 0.0 9.5e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 CEP06857.1 - 0.0019 17.7 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Dicty_REP PF05086.7 CEP06858.1 - 0.71 7.5 3.4 0.73 7.5 2.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Rap_GAP PF02145.10 CEP06859.1 - 9.1e-16 57.7 0.0 2.6e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP Myosin_head PF00063.16 CEP06860.1 - 2.7e-249 828.8 0.8 2.7e-249 828.8 0.6 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CEP06860.1 - 2.7e-31 107.5 4.8 2.7e-31 107.5 3.3 3.5 4 0 0 4 4 4 1 DIL domain IQ PF00612.22 CEP06860.1 - 1.8e-14 51.8 23.6 0.00015 21.0 0.3 6.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_22 PF13401.1 CEP06860.1 - 0.006 16.7 0.0 0.045 13.9 0.0 2.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 CEP06860.1 - 0.011 15.2 0.1 0.026 13.9 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 CEP06860.1 - 0.02 14.6 0.0 0.06 13.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CEP06860.1 - 0.028 14.4 0.0 0.028 14.4 0.0 3.7 3 1 0 3 3 3 0 AAA ATPase domain Sec7 PF01369.15 CEP06861.1 - 7e-24 84.5 0.5 7e-24 84.5 0.4 3.0 3 0 0 3 3 3 1 Sec7 domain PH PF00169.24 CEP06861.1 - 9.2e-05 22.5 0.2 0.062 13.5 0.1 2.9 2 0 0 2 2 2 2 PH domain PH_10 PF15411.1 CEP06861.1 - 0.0002 21.5 1.1 0.00073 19.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain FmdE PF02663.9 CEP06861.1 - 5.6 6.8 5.5 3.2 7.6 0.1 3.0 4 0 0 4 4 4 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DPBB_1 PF03330.13 CEP06862.1 - 7.3e-05 22.6 0.2 0.00013 21.9 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP06862.1 - 0.017 14.7 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Barwin family NIR_SIR PF01077.17 CEP06863.1 - 4e-49 165.9 0.1 8.4e-43 145.4 0.1 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 CEP06863.1 - 8.6e-32 110.0 0.5 2.7e-31 108.4 0.1 2.2 2 0 0 2 2 2 1 Flavodoxin NIR_SIR_ferr PF03460.12 CEP06863.1 - 4.5e-27 93.4 0.0 5.7e-14 51.4 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.14 CEP06863.1 - 3e-19 69.4 2.1 3e-19 69.4 1.4 2.6 3 0 0 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg APC_CDC26 PF10471.4 CEP06863.1 - 2.3 9.0 11.5 8.8 7.1 8.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 IL2 PF00715.12 CEP06864.1 - 0.0056 16.4 0.8 0.041 13.5 0.1 2.4 2 0 0 2 2 2 1 Interleukin 2 APG17 PF04108.7 CEP06864.1 - 0.059 12.1 6.3 0.036 12.8 1.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF3782 PF12644.2 CEP06864.1 - 0.086 12.6 0.6 0.23 11.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) HTH_Tnp_1 PF01527.15 CEP06865.1 - 0.032 14.1 0.2 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 Transposase Eapp_C PF10238.4 CEP06865.1 - 0.042 13.7 0.1 0.051 13.4 0.1 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein FUSC-like PF12805.2 CEP06865.1 - 0.12 11.2 0.2 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Peroxin-22 PF12827.2 CEP06867.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family DUF3473 PF11959.3 CEP06867.1 - 0.14 11.6 0.1 0.28 10.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3473) Pectate_lyase_3 PF12708.2 CEP06868.1 - 6.5e-06 26.4 3.9 0.0076 16.3 0.0 3.2 2 1 1 3 3 3 2 Pectate lyase superfamily protein NosD PF05048.8 CEP06868.1 - 0.05 12.7 11.6 2.1 7.4 4.6 2.5 2 1 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Ku PF02735.11 CEP06869.1 - 1.9e-39 135.1 0.0 3.2e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CEP06869.1 - 1.5e-36 125.9 1.3 2.2e-36 125.4 0.9 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 CEP06869.1 - 0.0038 17.3 0.1 0.01 15.9 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain UPF0300 PF08594.5 CEP06869.1 - 0.018 13.9 0.4 0.09 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0300) Arrestin_N PF00339.24 CEP06870.1 - 9.9e-17 61.1 0.0 2.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP06870.1 - 8.2e-09 35.6 0.0 2.6e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 CEP06870.1 - 9.1e-05 22.0 0.0 0.00063 19.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin_N terminal like Pkinase PF00069.20 CEP06871.1 - 6.4e-75 251.6 0.0 2.4e-74 249.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP06871.1 - 7.3e-39 133.3 0.0 1.9e-38 132.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP06871.1 - 4.1e-10 39.0 0.0 1.7e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF764 PF05561.6 CEP06871.1 - 0.0046 16.4 0.8 0.0096 15.3 0.6 1.4 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF764) Kdo PF06293.9 CEP06871.1 - 0.019 14.0 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP06871.1 - 0.027 14.1 0.3 0.059 13.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 CEP06871.1 - 0.042 13.1 1.0 0.073 12.4 0.1 1.8 2 0 0 2 2 2 0 RIO1 family PIP5K PF01504.13 CEP06872.1 - 3.8e-25 88.4 1.6 1.7e-12 46.9 0.1 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase RasGEF PF00617.14 CEP06873.1 - 5.7e-60 202.2 0.2 1.4e-59 200.9 0.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEP06873.1 - 8.9e-23 80.3 1.5 5.7e-22 77.7 1.0 2.4 1 1 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 CEP06873.1 - 1.7e-14 52.8 0.2 5e-14 51.4 0.2 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP06873.1 - 2.2e-12 46.3 1.5 2.3e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CEP06873.1 - 1.3e-10 40.6 0.1 2.6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 CEP06873.1 - 1.4e-06 27.9 7.9 0.00075 19.3 3.2 2.7 2 0 0 2 2 2 2 WW domain p450 PF00067.17 CEP06874.1 - 8.8e-82 275.0 0.0 1e-81 274.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_6 PF14259.1 CEP06875.1 - 1.4e-28 98.6 0.1 6.6e-08 32.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP06875.1 - 3.9e-18 64.8 0.0 3.6e-08 32.9 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP06875.1 - 7.2e-11 41.7 0.0 0.0001 22.0 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 CEP06875.1 - 0.0017 18.3 0.0 0.0055 16.7 0.0 1.8 2 0 0 2 2 2 1 Nmi/IFP 35 domain (NID) DUF4439 PF14530.1 CEP06876.1 - 0.0014 19.1 0.7 0.0019 18.6 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) Rib_recp_KP_reg PF05104.7 CEP06876.1 - 1.1 9.7 6.8 1.5 9.3 4.7 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Sporozoite_P67 PF05642.6 CEP06876.1 - 1.4 6.7 6.6 1.4 6.6 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apc15p PF05841.6 CEP06876.1 - 1.4 9.6 5.2 1.7 9.3 3.1 1.6 1 1 1 2 2 2 0 Apc15p protein MAP65_ASE1 PF03999.7 CEP06876.1 - 2.1 6.8 6.8 2.5 6.6 4.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Herpes_BLLF1 PF05109.8 CEP06876.1 - 2.5 5.9 15.3 3 5.6 10.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Ribosomal_L20 PF00453.13 CEP06877.1 - 0.035 14.0 0.8 0.066 13.1 0.1 1.7 1 1 0 1 1 1 0 Ribosomal protein L20 Exo_endo_phos_2 PF14529.1 CEP06878.1 - 1e-15 57.3 0.2 2.5e-12 46.4 0.2 2.8 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase RVT_1 PF00078.22 CEP06878.1 - 1.2e-08 34.6 0.5 2.4e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP06878.1 - 1.1e-05 25.4 0.1 0.0031 17.4 0.0 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Phage_integrase PF00589.17 CEP06880.1 - 0.00016 21.3 0.4 0.0031 17.1 0.3 2.1 1 1 0 1 1 1 1 Phage integrase family DUF3537 PF12056.3 CEP06881.1 - 0.016 13.9 0.5 0.024 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Hid1 PF12722.2 CEP06882.1 - 9.8 3.7 6.9 11 3.5 4.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RabGAP-TBC PF00566.13 CEP06884.1 - 2.2e-07 30.5 0.0 1.3e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SURF1 PF02104.10 CEP06885.1 - 6.3e-54 183.0 0.0 8.5e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 SURF1 family RRM_1 PF00076.17 CEP06886.1 - 7.1e-22 76.8 0.3 1.4e-21 75.8 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP06886.1 - 2.7e-18 65.6 0.1 4.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP06886.1 - 1.2e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BNR_3 PF13859.1 CEP06886.1 - 0.16 11.0 2.5 0.18 10.8 1.8 1.2 1 0 0 1 1 1 0 BNR repeat-like domain NifU_N PF01592.11 CEP06889.1 - 8.4e-52 174.4 0.1 9.7e-52 174.2 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Cyclin_N PF00134.18 CEP06890.1 - 1.3e-09 37.6 0.0 1.6e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CEP06890.1 - 5.8e-08 33.2 0.0 8.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin WD40 PF00400.27 CEP06891.1 - 9.5e-18 63.3 2.0 4.2e-06 26.4 1.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat PSII_BNR PF14870.1 CEP06891.1 - 0.00075 18.5 0.0 0.022 13.7 0.0 2.2 2 1 0 2 2 2 2 Photosynthesis system II assembly factor YCF48 S10_plectin PF03501.10 CEP06892.1 - 3.2e-43 145.5 0.1 3.8e-43 145.2 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HTH_45 PF14947.1 CEP06892.1 - 0.036 13.8 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix TrmB PF01978.14 CEP06892.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Kinase-like PF14531.1 CEP06892.1 - 0.11 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like XPA_C PF05181.7 CEP06893.1 - 1.4e-27 95.0 3.8 1.7e-27 94.7 1.0 2.4 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 CEP06893.1 - 0.026 14.1 2.5 0.058 13.0 1.7 1.6 1 0 0 1 1 1 0 XPA protein N-terminal Methyltransf_16 PF10294.4 CEP06894.1 - 1.7e-06 27.6 0.1 9.5e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 CEP06894.1 - 0.0014 18.2 0.0 0.0039 16.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP06894.1 - 0.015 15.0 0.0 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF2722 PF10846.3 CEP06894.1 - 0.1 11.5 0.7 0.15 11.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2457 PF10446.4 CEP06894.1 - 0.62 8.7 8.7 1.2 7.7 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CRCB PF02537.10 CEP06895.1 - 3e-30 104.5 13.3 2.6e-16 59.5 2.9 2.7 2 1 0 2 2 2 2 CrcB-like protein Acetyltransf_4 PF13420.1 CEP06896.1 - 4.9e-27 94.7 0.0 5.8e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP06896.1 - 1e-13 51.6 0.0 1.3e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP06896.1 - 9.3e-12 44.8 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP06896.1 - 8.9e-07 29.0 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP06896.1 - 1.2e-05 25.0 0.1 2.1e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CEP06896.1 - 3.7e-05 23.7 0.0 6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEP06896.1 - 8.5e-05 22.4 0.0 0.00021 21.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP06896.1 - 0.0016 18.2 0.0 0.0078 16.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 CEP06896.1 - 0.0059 16.5 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 Acetyltransf_CG PF14542.1 CEP06896.1 - 0.032 14.1 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short_C2 PF13561.1 CEP06897.1 - 1.3e-22 80.7 0.4 2.4e-22 79.8 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEP06897.1 - 2.1e-11 44.0 0.0 3.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEP06897.1 - 0.00026 20.7 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Herpes_BMRF2 PF04633.7 CEP06897.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein Dickkopf_N PF04706.7 CEP06898.1 - 0.23 11.6 7.5 0.62 10.2 5.2 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region EB PF01683.13 CEP06898.1 - 3.6 7.7 18.7 0.52 10.4 6.8 3.0 2 1 1 3 3 3 0 EB module Colipase PF01114.13 CEP06898.1 - 9.2 5.8 8.4 5 6.6 3.1 2.2 2 0 0 2 2 2 0 Colipase, N-terminal domain P12 PF12669.2 CEP06899.1 - 0.0086 16.2 0.0 0.0086 16.2 0.0 3.2 4 0 0 4 4 4 1 Virus attachment protein p12 family Dickkopf_N PF04706.7 CEP06899.1 - 1 9.5 8.0 3.2 7.9 5.5 1.8 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF1992 PF09350.5 CEP06900.1 - 1.9e-23 82.0 0.2 6.4e-23 80.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) RD3 PF14473.1 CEP06900.1 - 0.064 12.7 5.3 4.1 6.8 1.1 2.6 2 0 0 2 2 2 0 RD3 protein Mito_carr PF00153.22 CEP06901.1 - 4e-24 84.1 1.8 3e-16 58.8 0.0 3.5 3 1 0 3 3 3 2 Mitochondrial carrier protein Voltage_CLC PF00654.15 CEP06902.1 - 3.8e-90 302.4 30.3 1.2e-89 300.7 19.4 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CEP06902.1 - 2.3e-11 43.3 0.1 4.2e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain SNARE PF05739.14 CEP06903.1 - 3.3e-05 23.4 0.9 3.3e-05 23.4 0.6 3.0 3 0 0 3 3 3 2 SNARE domain V-SNARE_C PF12352.3 CEP06903.1 - 0.025 14.6 1.9 0.86 9.7 0.6 2.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nucleoporin_FG PF13634.1 CEP06903.1 - 0.3 11.3 15.2 1.1 9.5 10.6 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region HrpA_pilin PF09589.5 CEP06903.1 - 4.5 7.7 11.2 1.3e+02 3.0 7.8 2.7 1 1 0 1 1 1 0 HrpA pilus formation protein RNB PF00773.14 CEP06904.1 - 7.5e-48 163.4 0.0 3e-47 161.5 0.0 2.1 1 1 0 1 1 1 1 RNB domain Borrelia_P83 PF05262.6 CEP06905.1 - 0.51 8.5 27.3 0.88 7.7 18.9 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Plasmodium_Vir PF05795.6 CEP06905.1 - 8 5.5 8.8 10 5.1 3.6 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein F-box PF00646.28 CEP06906.1 - 0.62 9.7 3.6 4.9 6.9 2.5 2.5 1 1 0 1 1 1 0 F-box domain ICMT PF04140.9 CEP06907.1 - 5.3e-23 81.0 1.2 1.2e-22 79.9 0.8 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CEP06907.1 - 8.7e-11 41.8 0.5 8.7e-11 41.8 0.4 2.1 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 CEP06907.1 - 0.00013 21.3 3.5 0.00013 21.3 2.5 1.7 1 1 0 2 2 2 1 Protein of unknown function (DUF1295) Ist1 PF03398.9 CEP06908.1 - 4.2e-55 185.6 0.4 9.9e-55 184.4 0.3 1.7 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway UPF0220 PF05255.6 CEP06909.1 - 1.6e-38 131.5 0.0 2.9e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) zf-RING_4 PF14570.1 CEP06909.1 - 7.8e-18 63.8 6.3 1.5e-17 62.9 4.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 CEP06909.1 - 0.00036 20.3 0.2 0.0016 18.2 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP06909.1 - 0.00065 19.2 0.0 0.014 15.0 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CEP06909.1 - 0.0011 18.5 4.8 0.0022 17.6 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CEP06909.1 - 0.029 14.0 1.3 0.059 13.1 0.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF2243 PF10002.4 CEP06909.1 - 0.049 13.4 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) Nup35_RRM PF05172.8 CEP06909.1 - 0.05 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.1 CEP06909.1 - 0.089 12.8 7.2 0.16 12.0 5.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CEP06909.1 - 0.16 11.7 6.9 0.071 12.8 2.7 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger Peptidase_S49_N PF08496.5 CEP06909.1 - 7.5 6.3 10.5 5.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SWIM PF04434.12 CEP06910.1 - 0.00057 19.2 0.3 0.0013 18.1 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger XRN_N PF03159.13 CEP06912.1 - 8.5e-106 352.6 0.0 1.6e-105 351.7 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_3 PF13917.1 CEP06912.1 - 0.014 15.1 1.2 0.034 13.8 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 CEP06912.1 - 0.048 13.6 5.5 0.092 12.7 3.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Tweety PF04906.8 CEP06913.1 - 2.2 6.5 2.7 3.5 5.9 1.9 1.2 1 0 0 1 1 1 0 Tweety DUF4442 PF14539.1 CEP06915.1 - 0.0055 16.6 0.0 0.48 10.4 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4442) DUF328 PF03883.9 CEP06915.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF328) DDE_3 PF13358.1 CEP06917.1 - 3.4e-22 78.7 0.0 5e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP06917.1 - 3.1e-05 23.2 0.0 4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease EXS PF03124.9 CEP06919.1 - 1.3e-90 303.8 28.8 1.8e-90 303.4 20.0 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CEP06919.1 - 7.6e-31 107.8 18.9 9.4e-19 68.2 2.1 2.7 2 1 1 3 3 3 2 SPX domain RXT2_N PF08595.6 CEP06919.1 - 1.4 8.7 7.5 14 5.4 2.2 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Complex1_LYR PF05347.10 CEP06920.1 - 4.7e-05 23.0 1.7 0.00029 20.5 1.2 2.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEP06920.1 - 0.0041 17.2 1.5 0.0041 17.2 1.1 2.3 2 1 0 2 2 2 1 Complex1_LYR-like COG2 PF06148.6 CEP06920.1 - 0.34 10.7 2.7 0.27 11.0 0.2 2.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Toxin_55 PF15606.1 CEP06920.1 - 1.1 9.2 3.5 3.9 7.5 0.0 2.9 3 1 0 3 3 3 0 Putative toxin 55 Complex1_LYR_2 PF13233.1 CEP06920.1 - 4.3 7.8 7.9 11 6.5 5.5 2.1 1 1 0 1 1 1 0 Complex1_LYR-like Ribosomal_L30_N PF08079.7 CEP06921.1 - 3.1e-20 71.9 18.2 5.6e-20 71.1 12.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CEP06921.1 - 2.9e-18 65.2 0.9 5.4e-18 64.3 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Opi1 PF08618.5 CEP06922.1 - 7.2e-34 117.4 23.0 6.4e-21 74.7 0.9 4.6 1 1 4 5 5 5 4 Transcription factor Opi1 Perilipin PF03036.11 CEP06922.1 - 4.4e-07 29.0 0.4 1.4e-06 27.3 0.0 1.9 2 1 0 2 2 2 1 Perilipin family Pex14_N PF04695.8 CEP06922.1 - 0.75 9.8 9.6 0.067 13.2 1.0 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-CCCH PF00642.19 CEP06923.1 - 0.0002 20.9 2.9 0.00029 20.4 2.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1640 PF07798.6 CEP06925.1 - 1.2e-46 158.9 8.8 1.3e-46 158.8 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF342 PF03961.8 CEP06925.1 - 0.0016 16.9 3.6 0.0018 16.7 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) TBPIP PF07106.8 CEP06925.1 - 0.0036 16.8 5.0 0.0048 16.4 3.4 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Apolipoprotein PF01442.13 CEP06925.1 - 0.01 15.3 4.6 0.014 14.8 3.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.1 CEP06925.1 - 0.027 13.4 1.3 0.032 13.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.13 CEP06925.1 - 0.042 13.5 5.5 0.58 9.9 2.9 3.2 2 1 0 2 2 2 0 Homeobox associated leucine zipper Matrilin_ccoil PF10393.4 CEP06925.1 - 0.055 12.8 0.8 3.5 7.0 0.4 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin HAUS6_N PF14661.1 CEP06925.1 - 0.17 11.2 4.0 0.21 10.9 2.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YlqD PF11068.3 CEP06925.1 - 0.19 11.7 6.9 0.17 11.9 3.9 1.5 1 1 1 2 2 2 0 YlqD protein Bap31 PF05529.7 CEP06925.1 - 0.23 10.9 6.6 2 7.8 4.6 1.9 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like RAP1 PF07218.6 CEP06925.1 - 0.23 9.5 4.4 0.26 9.3 3.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pyr_redox PF00070.22 CEP06925.1 - 0.24 11.8 1.3 0.48 10.8 0.9 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4200 PF13863.1 CEP06925.1 - 0.36 10.7 11.8 0.52 10.2 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) GreA_GreB_N PF03449.10 CEP06925.1 - 0.4 10.7 7.9 1.1 9.3 5.0 2.1 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal DUF972 PF06156.8 CEP06925.1 - 0.49 10.7 8.0 3 8.2 4.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3166 PF11365.3 CEP06925.1 - 0.54 10.7 5.0 1.5 9.2 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) Fzo_mitofusin PF04799.8 CEP06925.1 - 0.7 9.2 4.5 1.7 7.9 2.8 1.7 1 1 1 2 2 2 0 fzo-like conserved region FlaC_arch PF05377.6 CEP06925.1 - 0.97 9.3 9.7 12 5.8 0.2 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 CEP06925.1 - 1 9.1 8.9 2.5 7.8 1.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF883 PF05957.8 CEP06925.1 - 2 8.8 4.7 3.9 7.9 2.6 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.4 CEP06925.1 - 2.3 7.0 8.2 3 6.7 5.4 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Remorin_C PF03763.8 CEP06925.1 - 5.2 6.6 8.7 4.6 6.8 5.0 1.7 1 1 1 2 2 2 0 Remorin, C-terminal region zf-rbx1 PF12678.2 CEP06926.1 - 3.8e-21 74.9 9.3 1.1e-20 73.4 6.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CEP06926.1 - 3.5e-11 42.7 7.9 9.8e-11 41.3 5.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CEP06926.1 - 6.3e-08 32.3 3.5 9.1e-08 31.8 2.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP06926.1 - 0.00018 21.4 1.4 0.0003 20.7 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP06926.1 - 0.00043 19.8 4.2 0.00087 18.9 2.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP06926.1 - 0.0022 17.5 1.2 0.0034 17.0 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP06926.1 - 0.044 13.5 2.5 0.072 12.8 1.7 1.4 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CEP06926.1 - 0.053 13.4 2.1 0.082 12.8 1.4 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain Asp PF00026.18 CEP06927.1 - 6.2e-40 137.3 3.7 1.8e-37 129.2 2.5 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP06927.1 - 4.7e-08 33.1 1.1 8.8e-08 32.2 0.2 1.8 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal ThiF PF00899.16 CEP06929.1 - 1.9e-15 56.8 0.7 4.3e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 ThiF family tRNA_m1G_MT PF01746.16 CEP06930.1 - 4.8e-38 130.6 0.7 8e-38 129.8 0.5 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase WWbp PF10349.4 CEP06930.1 - 0.0061 17.4 5.2 0.011 16.6 3.6 1.3 1 0 0 1 1 1 1 WW-domain ligand protein PP2C PF00481.16 CEP06932.1 - 1.5e-53 181.8 0.6 6.3e-53 179.7 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 CEP06932.1 - 4.2e-44 147.5 61.9 4.4e-06 26.1 0.0 13.6 8 5 7 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP06932.1 - 1e-42 143.7 51.5 2.1e-08 33.8 0.1 9.1 5 2 4 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 CEP06932.1 - 2.1e-24 81.7 57.6 0.044 13.8 0.0 19.1 21 0 0 21 21 21 10 Leucine Rich Repeat LRR_7 PF13504.1 CEP06932.1 - 1.4e-12 45.6 53.7 0.07 13.3 0.1 18.1 20 0 0 20 20 20 3 Leucine rich repeat RA PF00788.18 CEP06932.1 - 8e-12 45.4 0.2 2.6e-11 43.8 0.1 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 CEP06932.1 - 4.4e-06 26.2 37.7 3.5 8.0 0.0 13.3 12 1 1 13 13 13 2 Leucine Rich repeat CRM1_C PF08767.6 CEP06933.1 - 3.5e-06 26.1 0.6 3.5e-06 26.1 0.4 1.9 1 1 0 2 2 2 1 CRM1 C terminal rve PF00665.21 CEP06934.1 - 4.1e-13 49.4 0.0 6.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP06934.1 - 0.0043 16.5 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DNA_pol_A_exo1 PF01612.15 CEP06935.1 - 0.0018 17.8 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease CENP-F_leu_zip PF10473.4 CEP06936.1 - 0.0031 17.3 1.2 0.0031 17.3 0.9 2.4 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 CEP06936.1 - 0.013 15.3 1.2 0.013 15.3 0.8 2.9 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CEP06936.1 - 0.033 13.7 2.4 0.034 13.7 0.3 2.0 1 1 1 2 2 2 0 IncA protein HALZ PF02183.13 CEP06936.1 - 0.037 13.7 0.1 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 CEP06936.1 - 0.052 13.5 4.6 0.15 12.0 0.2 2.7 2 0 0 2 2 2 0 bZIP transcription factor zf-SNAP50_C PF12251.3 CEP06936.1 - 0.082 12.2 1.2 0.17 11.2 0.8 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal DivIC PF04977.10 CEP06936.1 - 0.11 12.0 1.9 0.72 9.3 1.2 2.5 1 1 0 1 1 1 0 Septum formation initiator Reo_sigmaC PF04582.7 CEP06936.1 - 0.52 9.4 11.3 0.098 11.8 4.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 CEP06936.1 - 1.1 9.0 7.7 0.14 11.8 1.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 CEP06936.1 - 2.1 8.2 13.7 0.036 13.9 2.7 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.6 CEP06936.1 - 3.4 7.7 10.9 0.12 12.4 1.2 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spectrin PF00435.16 CEP06936.1 - 5 7.4 9.1 22 5.4 0.2 2.8 3 0 0 3 3 3 0 Spectrin repeat Exo_endo_phos_2 PF14529.1 CEP06938.1 - 1.8e-09 37.2 0.3 4.8e-09 35.8 0.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP06938.1 - 2.9e-09 37.2 0.6 4.4e-09 36.6 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 CEP06939.1 - 1.5e-67 227.5 0.0 2.7e-67 226.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP06939.1 - 2.2e-34 118.7 0.0 3.8e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CEP06939.1 - 5.8e-18 64.3 31.9 9.8e-11 41.2 6.7 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 CEP06939.1 - 3.6e-14 52.2 6.9 1.1e-06 28.2 0.4 2.5 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 CEP06939.1 - 3.7e-09 36.9 0.2 1.3e-08 35.1 0.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEP06939.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.5 1 1 0 1 1 1 0 Kinase-like TFIIA PF03153.8 CEP06939.1 - 5.1 6.8 20.3 5.2 6.8 11.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit C1_2 PF03107.11 CEP06939.1 - 9.6 6.4 23.2 1.7 8.8 6.8 2.9 2 0 0 2 2 2 0 C1 domain Exo_endo_phos_2 PF14529.1 CEP06941.1 - 7.2e-14 51.4 0.2 9.9e-14 50.9 0.2 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP06941.1 - 1.2e-07 31.9 0.4 1.6e-07 31.5 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DNA_pol_E_B PF04042.11 CEP06941.1 - 0.081 12.1 1.1 5.1 6.2 0.0 2.3 1 1 1 2 2 2 0 DNA polymerase alpha/epsilon subunit B C1_1 PF00130.17 CEP06942.1 - 2.7e-11 43.0 18.4 2.7e-07 30.1 5.2 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.1 CEP06942.1 - 6.2e-05 21.5 0.3 0.0002 19.8 0.0 1.8 2 0 0 2 2 2 1 Cation-channel complex subunit UNC-79 C1_3 PF07649.7 CEP06942.1 - 0.0095 15.9 3.3 0.0095 15.9 2.3 2.5 2 0 0 2 2 2 2 C1-like domain PHD PF00628.24 CEP06942.1 - 0.035 13.7 15.8 0.16 11.6 1.0 2.6 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 CEP06942.1 - 0.31 10.7 13.0 2.1 8.1 3.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3371 PF11851.3 CEP06943.1 - 0.28 11.8 7.1 1.4 9.6 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Ctr PF04145.10 CEP06943.1 - 0.92 9.5 3.1 0.72 9.9 0.7 1.8 2 0 0 2 2 2 0 Ctr copper transporter family LRR_6 PF13516.1 CEP06944.1 - 6.4e-16 56.6 17.1 0.22 11.7 0.1 9.7 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.2 CEP06944.1 - 2.7e-13 49.1 0.5 0.0029 17.1 0.6 5.6 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP06944.1 - 2.8e-10 38.7 15.1 2.6 8.4 0.1 9.9 9 2 0 9 9 9 3 Leucine Rich Repeat LRR_7 PF13504.1 CEP06944.1 - 1.6e-06 27.3 18.8 3.9 8.0 0.1 9.9 11 0 0 11 11 11 1 Leucine rich repeat LRR_8 PF13855.1 CEP06944.1 - 5.8e-06 25.9 10.1 0.19 11.4 2.0 5.1 2 1 3 5 5 5 4 Leucine rich repeat DUF1699 PF08004.6 CEP06944.1 - 0.035 13.6 0.1 3.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) Ste50p-SAM PF09235.5 CEP06944.1 - 1 9.4 14.5 2.2 8.3 0.7 5.2 4 3 2 6 6 6 0 Ste50p, sterile alpha motif rve PF00665.21 CEP06946.1 - 3.8e-22 78.6 0.0 7.1e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP06946.1 - 6e-09 35.4 1.2 1.2e-08 34.4 0.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 CEP06946.1 - 0.029 14.2 0.2 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 rve_3 PF13683.1 CEP06946.1 - 0.052 13.0 0.1 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.22 CEP06947.1 - 3.2e-23 82.2 0.1 6.6e-23 81.1 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OCIA PF07051.6 CEP06947.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) OrfB_Zn_ribbon PF07282.6 CEP06951.1 - 0.025 14.2 0.1 0.28 10.8 0.0 2.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain RRM_5 PF13893.1 CEP06952.1 - 3e-06 26.9 0.1 7.9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP06952.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fibrinogen_BP PF08017.6 CEP06952.1 - 0.0028 15.9 4.5 0.0041 15.4 3.1 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein RRM_3 PF08777.6 CEP06952.1 - 0.0097 15.7 0.0 0.03 14.1 0.0 1.9 1 0 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 CEP06952.1 - 0.077 12.9 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 CEP06953.1 - 3.9e-24 84.7 0.2 2.1e-10 40.5 0.0 3.4 2 0 0 2 2 2 2 Calponin homology (CH) domain GAS2 PF02187.12 CEP06953.1 - 8.4e-08 31.8 0.1 2.9e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.3 CEP06953.1 - 4e-06 26.3 0.1 0.00043 19.8 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain RVT_1 PF00078.22 CEP06955.1 - 8.6e-14 51.3 0.9 1.6e-13 50.5 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP06955.1 - 1.2e-06 28.8 0.0 2.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Pneumo_M2 PF07380.6 CEP06956.1 - 0.034 14.1 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Pneumovirus M2 protein CcdB PF01845.12 CEP06956.1 - 0.06 13.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 CcdB protein RA PF00788.18 CEP06957.1 - 2.8e-11 43.7 0.0 1.4e-06 28.7 0.0 3.4 2 1 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 CEP06957.1 - 2e-05 23.9 0.0 4.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP06957.1 - 0.00071 19.0 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP06957.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF221 PF02714.10 CEP06958.1 - 4.8e-81 272.1 20.3 4.8e-81 272.1 14.1 2.6 2 1 0 2 2 2 1 Domain of unknown function DUF221 DUF4463 PF14703.1 CEP06958.1 - 1.9e-12 47.5 0.9 4.1e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) CPSase_L_D2 PF02786.12 CEP06959.1 - 7.6e-78 260.6 0.1 1.5e-77 259.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CEP06959.1 - 3e-68 229.1 0.0 5.6e-68 228.2 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CEP06959.1 - 2.3e-34 117.7 0.0 1.1e-33 115.6 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CEP06959.1 - 1.5e-30 105.3 0.0 4.5e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CEP06959.1 - 7.4e-30 104.3 0.1 1.4e-29 103.4 0.1 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 CEP06959.1 - 4.9e-17 62.2 0.1 9.6e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP06959.1 - 1.1e-16 60.5 0.2 3.6e-16 58.8 0.0 1.9 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CEP06959.1 - 2.5e-16 59.0 4.2 1.2e-15 56.8 1.1 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CEP06959.1 - 5.4e-10 39.0 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CEP06959.1 - 1.1e-09 37.7 2.3 7.6e-05 22.2 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.6 CEP06959.1 - 1.6e-07 30.9 0.2 9.2e-07 28.5 0.1 2.3 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 CEP06959.1 - 2.3e-07 30.3 0.0 4.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CEP06959.1 - 6e-07 29.7 1.1 0.087 13.1 0.0 3.8 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 CEP06959.1 - 8.2e-05 22.5 0.0 0.00028 20.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain HlyD PF00529.15 CEP06959.1 - 0.00013 21.4 0.6 0.03 13.6 0.1 2.6 1 1 1 2 2 2 2 HlyD family secretion protein SAC3_GANP PF03399.11 CEP06960.1 - 3.7e-50 170.3 5.3 6.7e-50 169.4 3.7 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Sec63 PF02889.11 CEP06961.1 - 6.3e-212 702.3 0.8 7.6e-113 376.8 0.2 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CEP06961.1 - 2.1e-54 183.5 0.1 5e-30 104.2 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CEP06961.1 - 8e-16 58.3 0.0 1.2e-09 38.3 0.0 4.2 5 0 0 5 5 5 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEP06961.1 - 3e-12 46.2 0.0 7.7e-09 35.3 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CEP06961.1 - 1.5e-06 28.3 0.1 0.015 15.4 0.0 3.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CEP06961.1 - 0.00033 19.9 0.0 0.046 12.9 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein AAA_10 PF12846.2 CEP06961.1 - 0.0018 17.7 0.9 1.2 8.4 0.0 4.0 4 1 1 5 5 5 1 AAA-like domain AAA_19 PF13245.1 CEP06961.1 - 0.01 15.5 0.0 1.3 8.8 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain rve PF00665.21 CEP06962.1 - 5.5e-18 65.2 0.0 6.5e-17 61.7 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CEP06962.1 - 3.5e-13 49.4 1.7 8.8e-13 48.0 1.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CEP06962.1 - 1.4e-10 40.6 0.2 3.8e-10 39.2 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP06962.1 - 2.9e-05 23.3 1.5 6.1e-05 22.3 1.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve PF00665.21 CEP06963.1 - 3.8e-23 81.8 0.0 6.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP06963.1 - 0.00035 20.0 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP06964.1 - 6.3e-16 58.3 1.1 1.1e-15 57.5 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP06964.1 - 2.2e-06 28.0 0.2 6e-06 26.6 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP06964.1 - 0.00062 19.5 0.0 0.0019 17.9 0.1 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 CEP06964.1 - 0.0023 17.5 0.0 0.043 13.3 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 CEP06964.1 - 0.0027 17.6 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CEP06964.1 - 0.19 11.8 2.3 16 5.6 0.2 3.1 2 1 1 3 3 3 0 Retrotransposon gag protein Retrotrans_gag PF03732.12 CEP06966.1 - 0.0029 17.6 0.1 0.0057 16.6 0.1 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein PACT_coil_coil PF10495.4 CEP06966.1 - 0.079 12.8 0.3 0.25 11.2 0.2 1.9 1 1 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Exo_endo_phos PF03372.18 CEP06967.1 - 5.9e-11 42.7 1.1 9.8e-11 42.0 0.8 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP06967.1 - 2.9e-10 39.8 1.8 8e-10 38.3 0.2 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 CEP06967.1 - 0.0002 21.0 15.7 0.0052 16.6 1.6 2.6 2 0 0 2 2 2 2 Zinc knuckle PHD PF00628.24 CEP06968.1 - 2.6e-06 26.9 17.1 4.6e-06 26.2 7.9 2.6 2 0 0 2 2 2 1 PHD-finger PBP1_TM PF14812.1 CEP06968.1 - 1.3 9.3 4.7 2.1 8.7 1.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_jaz PF12171.3 CEP06968.1 - 1.4 9.1 7.9 0.31 11.2 2.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding F-box-like PF12937.2 CEP06969.1 - 0.0023 17.6 0.2 0.0069 16.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like LAG1-DNAbind PF09271.6 CEP06970.1 - 8.1e-35 120.3 3.5 7e-34 117.2 0.1 3.4 3 0 0 3 3 3 1 LAG1, DNA binding BTD PF09270.5 CEP06970.1 - 9.5e-26 90.4 0.3 1.7e-15 57.1 0.0 3.5 3 0 0 3 3 3 3 Beta-trefoil DNA-binding domain DUF2003 PF09404.5 CEP06971.1 - 9.6e-34 116.5 1.1 4.9e-33 114.2 0.7 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF2003) RPA_interact_M PF14767.1 CEP06971.1 - 0.051 14.3 1.2 0.13 13.0 0.1 2.1 2 0 0 2 2 2 0 Replication protein A interacting middle AhpC-TSA PF00578.16 CEP06973.1 - 4e-20 71.7 0.0 5.5e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEP06973.1 - 2.2e-06 27.2 0.0 3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin NUC153 PF08159.7 CEP06974.1 - 2.9e-13 49.1 0.9 5.1e-13 48.3 0.6 1.4 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 CEP06974.1 - 0.0089 15.8 0.1 0.41 10.6 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat GSK-3_bind PF05350.7 CEP06974.1 - 0.016 14.6 0.7 0.025 14.0 0.5 1.2 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding AbfB PF05270.8 CEP06974.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) Nop14 PF04147.7 CEP06974.1 - 0.065 11.1 18.5 0.12 10.2 12.8 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CEP06974.1 - 9.3 4.1 12.6 13 3.6 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Sas10_Utp3 PF04000.10 CEP06975.1 - 2.5 8.3 7.3 6 7.1 0.2 3.2 4 0 0 4 4 4 0 Sas10/Utp3/C1D family DUF459 PF04311.8 CEP06977.1 - 0.01 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) DDE_3 PF13358.1 CEP06978.1 - 5.2e-32 110.6 0.1 7.4e-32 110.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP06978.1 - 4.8e-05 22.6 0.2 0.00014 21.1 0.1 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease U3_snoRNA_assoc PF08297.6 CEP06978.1 - 0.088 13.0 3.0 0.2 11.9 2.1 1.6 1 0 0 1 1 1 0 U3 snoRNA associated RVT_1 PF00078.22 CEP06979.1 - 3.4e-24 85.3 0.1 6.3e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP06979.1 - 1.2e-16 60.9 0.0 2.7e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CEP06979.1 - 3.7e-08 33.7 0.0 1.1e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CEP06979.1 - 0.00012 21.9 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Collagen PF01391.13 CEP06979.1 - 0.00017 21.0 5.3 0.00017 21.0 3.6 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) zf-CCHC PF00098.18 CEP06979.1 - 0.00048 19.9 1.1 0.00048 19.9 0.8 2.5 2 0 0 2 2 2 1 Zinc knuckle gag_pre-integrs PF13976.1 CEP06979.1 - 0.01 15.4 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 GAG-pre-integrase domain RVP PF00077.15 CEP06979.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.1 CEP06979.1 - 0.024 14.1 0.0 0.076 12.5 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.1 CEP06979.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HAD PF12710.2 CEP06980.1 - 2.8e-20 73.3 0.1 1.4e-19 71.0 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEP06980.1 - 5.3e-17 61.6 0.0 1.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEP06980.1 - 1.2e-15 58.4 1.3 8.2e-14 52.5 0.9 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP06980.1 - 7.5e-13 48.2 0.0 2.1e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEP06980.1 - 0.00056 19.5 0.0 0.0048 16.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP06980.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Exo_endo_phos PF03372.18 CEP06981.1 - 9.7e-13 48.6 0.4 1.4e-12 48.0 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP06981.1 - 2.1e-06 27.3 1.0 3.8e-05 23.2 0.2 2.7 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Phage_integrase PF00589.17 CEP06982.1 - 0.00047 19.8 0.0 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 CEP06982.1 - 0.0019 18.3 0.1 0.0057 16.7 0.1 1.8 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 CEP06982.1 - 0.056 13.7 0.0 0.2 12.0 0.0 1.9 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PMG PF05287.7 CEP06982.1 - 0.099 12.4 3.5 0.088 12.6 0.7 1.8 1 1 1 2 2 2 0 PMG protein PALP PF00291.20 CEP06983.1 - 4.8e-67 226.3 0.1 5.8e-67 226.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2422 PF10337.4 CEP06984.1 - 4.1e-23 81.9 15.3 4.1e-23 81.9 10.6 3.0 2 2 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CEP06984.1 - 5.2e-17 62.2 0.1 1.4e-16 60.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 CEP06984.1 - 6.1e-08 32.6 22.6 6.1e-08 32.6 15.7 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 CEP06984.1 - 0.00047 18.9 5.2 0.00047 18.9 3.6 2.1 3 0 0 3 3 3 1 Aluminium activated malate transporter HAUS4 PF14735.1 CEP06984.1 - 0.24 10.6 5.9 0.071 12.4 1.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 TPR_11 PF13414.1 CEP06985.1 - 0.025 14.2 5.6 0.031 13.8 0.0 3.8 4 1 1 5 5 5 0 TPR repeat DDE_3 PF13358.1 CEP06987.1 - 7.3e-28 97.1 0.0 1.3e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP06987.1 - 0.00022 21.1 0.3 0.00069 19.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP06987.1 - 0.00025 21.7 0.0 0.0007 20.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 CEP06987.1 - 0.00085 18.8 0.1 0.0029 17.2 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_psq PF05225.11 CEP06987.1 - 0.002 17.6 0.0 0.0048 16.4 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1804 PF08822.6 CEP06987.1 - 0.0023 17.7 0.1 0.02 14.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1804) HTH_29 PF13551.1 CEP06987.1 - 0.0038 17.3 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix DDE_1 PF03184.14 CEP06987.1 - 0.014 14.5 0.1 0.12 11.4 0.1 2.4 1 1 0 1 1 1 0 DDE superfamily endonuclease rve PF00665.21 CEP06987.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_7 PF02796.10 CEP06987.1 - 0.064 13.1 0.0 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase PPP4R2 PF09184.6 CEP06988.1 - 0.66 9.4 22.6 1.1 8.7 15.6 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 CEP06988.1 - 2 6.3 26.3 2.8 5.8 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 CEP06988.1 - 3.7 6.4 12.8 5.6 5.8 8.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2457 PF10446.4 CEP06988.1 - 6.2 5.4 35.6 10 4.7 24.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) COG7 PF10191.4 CEP06989.1 - 4.1e-14 51.4 7.1 8.4e-14 50.4 4.9 1.4 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) TPR_11 PF13414.1 CEP06989.1 - 1.1e-11 44.1 3.6 2.2e-10 40.0 0.4 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 CEP06989.1 - 3.6e-08 32.6 5.3 0.00043 19.7 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP06989.1 - 2.4e-07 30.1 4.9 0.083 12.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.26 CEP06989.1 - 0.0017 18.1 0.3 0.0056 16.4 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.1 CEP06989.1 - 0.047 13.6 3.6 2.5 8.1 0.7 3.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEP06989.1 - 5.4 7.8 7.9 33 5.3 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PCI PF01399.22 CEP06990.1 - 2.1e-22 79.3 1.0 2.1e-22 79.3 0.7 2.9 4 0 0 4 4 4 1 PCI domain PCI_Csn8 PF10075.4 CEP06990.1 - 3e-14 52.9 0.5 3e-14 52.9 0.3 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 CEP06990.1 - 0.034 13.9 0.3 53 3.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF605 PF04652.11 CEP06991.1 - 3e-79 267.1 32.4 2.2e-76 257.7 22.4 2.0 1 1 0 1 1 1 1 Vta1 like Totivirus_coat PF05518.6 CEP06991.1 - 1.8 6.2 8.1 1.9 6.2 5.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein TFIIA PF03153.8 CEP06991.1 - 3 7.6 8.8 3.9 7.2 6.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CEP06991.1 - 4.2 5.4 22.6 5.3 5.1 15.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fork_head PF00250.13 CEP06992.1 - 8.4e-30 102.6 0.2 1.7e-29 101.7 0.1 1.5 1 0 0 1 1 1 1 Fork head domain Peptidase_M41 PF01434.13 CEP06992.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 LRR_6 PF13516.1 CEP06994.1 - 3.5e-12 45.0 16.6 0.27 11.4 0.0 10.5 11 0 0 11 11 11 3 Leucine Rich repeat CsbD PF05532.7 CEP06994.1 - 5e-11 42.1 4.3 1.5e-10 40.6 3.0 1.8 1 0 0 1 1 1 1 CsbD-like LRR_4 PF12799.2 CEP06994.1 - 8.6e-07 28.4 13.8 1.5 8.5 0.0 7.0 4 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP06994.1 - 6.4e-05 22.4 8.1 45 4.6 0.0 8.6 10 0 0 10 10 10 0 Leucine Rich Repeat GAT PF03127.9 CEP06994.1 - 0.00053 19.9 0.7 0.00053 19.9 0.5 2.9 3 0 0 3 3 3 1 GAT domain LRR_7 PF13504.1 CEP06994.1 - 0.011 15.7 12.7 86 4.0 0.0 8.8 11 0 0 11 11 11 0 Leucine rich repeat DUF1054 PF06335.7 CEP06994.1 - 0.59 9.7 7.7 1 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) AAA_8 PF12780.2 CEP06995.1 - 0.054 12.4 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Pil1 PF13805.1 CEP06996.1 - 3.8e-35 121.3 2.4 3.8e-35 121.3 1.7 1.6 2 0 0 2 2 2 1 Eisosome component PIL1 Sec34 PF04136.10 CEP06997.1 - 5.1e-35 120.4 1.6 5.1e-35 120.4 1.1 2.2 2 0 0 2 2 2 1 Sec34-like family ACDC PF14733.1 CEP06997.1 - 0.04 14.0 0.3 0.77 9.9 0.0 3.3 2 1 0 2 2 2 0 AP2-coincident C-terminal DUF21 PF01595.15 CEP06998.1 - 2.6e-28 98.5 7.1 4.9e-28 97.6 4.9 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CEP06998.1 - 4.3e-05 23.2 0.6 0.021 14.6 0.1 2.6 2 0 0 2 2 2 2 CBS domain Rhomboid PF01694.17 CEP06998.1 - 9.3 6.2 12.1 74 3.3 8.4 2.2 1 1 1 2 2 2 0 Rhomboid family F-box PF00646.28 CEP06999.1 - 2.8e-07 30.0 0.8 6.2e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CEP06999.1 - 1.1e-05 25.0 0.4 4e-05 23.2 0.2 2.2 2 0 0 2 2 2 1 F-box-like DUF3990 PF13151.1 CEP06999.1 - 0.022 14.1 0.5 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) PTSIIB_sorb PF03830.10 CEP06999.1 - 0.17 11.7 0.0 0.96 9.3 0.0 2.2 3 0 0 3 3 3 0 PTS system sorbose subfamily IIB component V_ATPase_I PF01496.14 CEP07000.1 - 1.5e-283 942.3 10.9 1.7e-283 942.1 7.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family KLRAQ PF10205.4 CEP07000.1 - 0.12 12.4 2.2 0.32 11.0 1.5 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF948 PF06103.6 CEP07000.1 - 0.12 12.2 2.8 0.67 9.8 0.6 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BAR PF03114.13 CEP07001.1 - 2e-31 109.2 11.0 2.8e-31 108.7 7.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 CEP07001.1 - 1.2e-14 53.5 0.3 2.2e-14 52.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP07001.1 - 2.7e-13 49.0 0.1 5e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP07001.1 - 2.2e-08 33.4 0.1 4.1e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3138 PF11336.3 CEP07002.1 - 0.03 12.4 0.1 0.041 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pkinase PF00069.20 CEP07003.1 - 4.7e-12 45.5 0.0 7.1e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07003.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.1 CEP07003.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Abhydrolase_6 PF12697.2 CEP07004.1 - 2.7e-25 89.5 0.0 3.5e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP07004.1 - 1.2e-07 31.5 0.0 1.3e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP07004.1 - 0.016 14.7 0.1 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold PRESAN PF09687.5 CEP07004.1 - 0.098 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Plasmodium RESA N-terminal zf-HIT PF04438.11 CEP07005.1 - 1.5e-10 40.4 11.8 2.4e-10 39.8 8.2 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF1981 PF09324.5 CEP07005.1 - 0.083 12.4 1.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) zf-C2H2_6 PF13912.1 CEP07005.1 - 1.5 8.8 5.4 4.3 7.3 0.3 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger PseudoU_synth_1 PF01416.15 CEP07006.1 - 3.8e-19 69.0 0.0 5.2e-09 36.4 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase OEP PF02321.13 CEP07006.1 - 0.04 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein DUF3665 PF12427.3 CEP07006.1 - 0.81 9.1 3.7 11 5.5 0.3 2.5 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase adh_short PF00106.20 CEP07007.1 - 5.9e-27 94.6 2.2 7.6e-27 94.2 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP07007.1 - 4e-25 88.9 1.8 4.7e-25 88.7 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP07007.1 - 4.9e-08 32.8 2.7 2.1e-07 30.8 1.8 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CEP07007.1 - 0.0013 18.1 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CEP07007.1 - 0.002 18.2 0.2 0.0066 16.5 0.1 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CEP07007.1 - 0.0047 15.9 0.2 0.007 15.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF676 PF05057.9 CEP07008.1 - 1.2e-42 145.6 0.1 1.9e-42 145.0 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CEP07008.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CEP07008.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CEP07008.1 - 0.005 16.4 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CEP07008.1 - 0.006 16.4 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP07008.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PLDc_N PF13396.1 CEP07008.1 - 0.52 10.0 3.5 1.2 8.8 2.4 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal C2 PF00168.25 CEP07009.1 - 8.7e-21 73.5 0.3 1.2e-20 73.1 0.2 1.1 1 0 0 1 1 1 1 C2 domain NT-C2 PF10358.4 CEP07009.1 - 0.037 13.5 0.1 0.045 13.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Glyco_transf_21 PF13506.1 CEP07010.1 - 9.5e-40 135.7 0.0 1.4e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 CEP07010.1 - 3.9e-25 88.9 0.0 5.1e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEP07010.1 - 1.3e-16 60.9 1.7 2.1e-16 60.2 1.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CEP07010.1 - 2.9e-05 23.7 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 MAM33 PF02330.11 CEP07011.1 - 2.1e-28 99.5 12.5 5.2e-28 98.1 8.7 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein Ribosomal_S13 PF00416.17 CEP07011.1 - 0.19 12.2 1.5 0.34 11.3 1.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 DUF1451 PF07295.6 CEP07011.1 - 0.87 9.3 5.8 2.7 7.7 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DUF4201 PF13870.1 CEP07012.1 - 0.0054 16.1 1.7 0.012 15.0 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3658 PF12395.3 CEP07012.1 - 0.033 13.7 0.9 0.057 12.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function RP-C_C PF11800.3 CEP07012.1 - 0.082 12.6 1.8 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF948 PF06103.6 CEP07012.1 - 0.084 12.7 3.1 0.8 9.6 0.0 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.9 CEP07012.1 - 2 8.3 9.0 0.032 14.1 0.8 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) tRNA-synt_1d PF00750.14 CEP07013.1 - 3e-91 305.8 7.2 4.6e-91 305.2 5.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CEP07013.1 - 4.4e-23 81.4 0.0 1.6e-22 79.6 0.0 2.1 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CEP07013.1 - 1.1e-08 35.4 0.0 4.2e-08 33.6 0.0 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GST_C_2 PF13410.1 CEP07013.1 - 3.4e-05 23.6 0.2 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EMP70 PF02990.11 CEP07014.1 - 4e-199 662.4 5.4 4.9e-199 662.1 3.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SNF2_N PF00176.18 CEP07015.1 - 4.7e-78 262.0 4.4 9.8e-70 234.6 0.7 2.8 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP07015.1 - 2.7e-14 52.7 0.0 1.4e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP07015.1 - 2.8e-06 26.9 0.8 0.00012 21.6 0.4 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase E1-E2_ATPase PF00122.15 CEP07016.1 - 1.3e-56 191.1 1.2 1.3e-56 191.1 0.8 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP07016.1 - 2.5e-44 150.9 10.0 2.5e-44 150.9 6.9 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP07016.1 - 9.9e-27 94.7 0.0 3.1e-26 93.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP07016.1 - 2.8e-20 72.0 0.0 5.4e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP07016.1 - 1.8e-13 51.0 0.0 4.6e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP07016.1 - 1.2e-10 40.6 0.0 4.6e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP07016.1 - 6e-06 26.0 0.1 0.00091 18.8 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.26 CEP07017.1 - 1.4e-13 50.3 3.7 1.8e-13 49.9 1.8 1.7 2 0 0 2 2 2 1 DnaJ domain Gly-zipper_YMGG PF13441.1 CEP07017.1 - 0.00022 20.6 4.0 0.00041 19.8 2.8 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 CEP07017.1 - 0.00066 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CEP07017.1 - 0.001 18.6 4.5 0.0022 17.5 3.1 1.5 1 0 0 1 1 1 1 Glycine zipper DUF456 PF04306.8 CEP07017.1 - 0.0092 16.0 0.8 0.015 15.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.4 CEP07017.1 - 0.026 14.6 3.6 0.051 13.7 2.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 CEP07017.1 - 0.74 9.5 9.5 2.4 7.9 6.6 1.8 1 1 0 1 1 1 0 Glycine zipper 2TM domain dCMP_cyt_deam_1 PF00383.17 CEP07018.1 - 3.6e-09 36.1 0.1 4.9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Apolipoprotein PF01442.13 CEP07019.1 - 0.00033 20.2 1.4 0.00056 19.4 0.4 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain AAA_32 PF13654.1 CEP07019.1 - 0.0049 15.6 0.6 0.0067 15.1 0.4 1.1 1 0 0 1 1 1 1 AAA domain Herpes_U30 PF04523.8 CEP07019.1 - 0.011 13.1 1.6 0.016 12.6 1.1 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 CENP-K PF11802.3 CEP07019.1 - 0.069 12.3 1.1 0.14 11.3 0.6 1.5 1 1 1 2 2 2 0 Centromere-associated protein K Baculo_p24 PF05073.7 CEP07019.1 - 0.077 12.5 1.4 0.11 11.9 1.0 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein ABC1 PF03109.11 CEP07019.1 - 0.11 12.5 1.9 0.14 12.1 0.6 1.6 2 0 0 2 2 2 0 ABC1 family Fib_alpha PF08702.5 CEP07019.1 - 0.53 10.4 4.1 0.83 9.7 2.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DNA_pol_A PF00476.15 CEP07021.1 - 3.5e-91 305.6 0.0 5e-91 305.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 CEP07021.1 - 0.0073 15.8 0.8 0.026 14.0 0.6 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Peroxin-13_N PF04088.8 CEP07022.1 - 6.9e-53 178.8 0.0 1.1e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 CEP07022.1 - 3.3e-12 45.6 0.0 6e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP07022.1 - 6e-11 41.5 0.0 1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP07022.1 - 4e-10 39.1 0.0 6.7e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vesiculo_matrix PF06326.7 CEP07022.1 - 0.044 13.2 0.1 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Vesiculovirus matrix protein HSF_DNA-bind PF00447.12 CEP07023.1 - 1.3e-33 115.2 0.7 1.3e-33 115.2 0.5 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 CEP07023.1 - 5.7e-26 90.7 0.1 1.1e-25 89.7 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DivIC PF04977.10 CEP07023.1 - 0.0046 16.4 0.2 0.0099 15.3 0.1 1.6 1 0 0 1 1 1 1 Septum formation initiator Prominin PF05478.6 CEP07023.1 - 0.42 8.0 2.0 0.6 7.5 1.4 1.1 1 0 0 1 1 1 0 Prominin RRM_1 PF00076.17 CEP07024.1 - 8.5e-39 131.0 0.0 5e-20 70.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07024.1 - 2.8e-20 72.0 0.0 3.9e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07024.1 - 1.9e-17 62.8 0.0 2.1e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CEP07024.1 - 0.00016 21.3 0.1 0.69 9.7 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 CEP07024.1 - 0.00032 20.1 0.3 0.022 14.2 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain SMN PF06003.7 CEP07024.1 - 0.84 8.6 4.2 1.2 8.2 2.9 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RCC1 PF00415.13 CEP07025.1 - 1.1e-36 124.7 29.8 1.4e-09 38.0 0.1 9.6 7 3 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat ApbA PF02558.11 CEP07025.1 - 3.8e-32 110.8 0.0 8.8e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RCC1_2 PF13540.1 CEP07025.1 - 6.2e-31 105.3 35.8 1.1e-06 28.0 4.4 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat ApbA_C PF08546.6 CEP07025.1 - 5.9e-28 97.3 0.1 1e-27 96.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Ribosomal_S7 PF00177.16 CEP07025.1 - 0.11 12.1 0.2 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e GUCT PF08152.7 CEP07026.1 - 0.022 14.7 0.3 4.8 7.2 0.0 2.8 3 0 0 3 3 3 0 GUCT (NUC152) domain adh_short PF00106.20 CEP07027.1 - 4.9e-23 81.8 0.0 6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP07027.1 - 2.3e-07 30.8 0.0 2.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP07027.1 - 8.5e-07 28.8 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CEP07027.1 - 2.3e-05 23.9 0.5 5.6e-05 22.6 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3472 PF11958.3 CEP07028.1 - 5.3e-28 98.6 3.2 6.7e-28 98.2 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) BNR PF02012.15 CEP07028.1 - 0.0012 18.3 0.3 0.0048 16.5 0.2 2.1 1 0 0 1 1 1 1 BNR/Asp-box repeat Asp PF00026.18 CEP07029.1 - 1.2e-55 189.0 2.4 2.1e-55 188.2 1.6 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP07029.1 - 9.6e-12 45.1 1.6 1.6e-11 44.4 1.1 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Sec5 PF15469.1 CEP07030.1 - 4.5e-26 91.7 3.6 1.2e-25 90.3 2.5 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 CEP07030.1 - 2.2e-25 88.2 1.4 2.2e-25 88.2 0.9 2.5 3 0 0 3 3 3 1 Vps51/Vps67 Dor1 PF04124.7 CEP07030.1 - 1e-14 53.7 7.4 4.8e-14 51.5 5.1 2.1 1 1 0 1 1 1 1 Dor1-like family DUF2450 PF10475.4 CEP07030.1 - 1.6e-10 40.4 3.5 3e-10 39.5 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CEP07030.1 - 8.1e-06 25.7 3.2 0.00013 21.8 1.0 3.2 2 2 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 CEP07030.1 - 1.3e-05 25.1 1.8 1.3e-05 25.1 1.2 2.9 2 1 1 3 3 3 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.4 CEP07030.1 - 7.5e-05 22.6 1.1 0.00024 20.9 0.7 1.9 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 CEP07030.1 - 0.0015 18.2 0.9 0.0047 16.6 0.6 2.0 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Nsp1_C PF05064.8 CEP07030.1 - 0.0075 15.8 2.4 0.014 15.0 0.7 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region Vps53_N PF04100.7 CEP07030.1 - 0.026 13.2 5.6 0.05 12.3 3.9 1.5 1 0 0 1 1 1 0 Vps53-like, N-terminal Sec8_exocyst PF04048.9 CEP07030.1 - 0.085 12.4 6.6 0.059 13.0 2.8 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF972 PF06156.8 CEP07030.1 - 0.31 11.3 3.8 1 9.7 1.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) LysM PF01476.15 CEP07032.1 - 2.8e-09 36.7 0.0 4.3e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 LysM domain Pex14_N PF04695.8 CEP07032.1 - 0.0052 16.8 8.1 0.0052 16.8 5.6 1.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1638 PF07796.6 CEP07032.1 - 0.011 15.4 0.1 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) DUF913 PF06025.7 CEP07032.1 - 0.018 13.7 2.1 0.025 13.3 1.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1314 PF07013.6 CEP07032.1 - 0.17 11.2 1.7 0.63 9.4 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1314) DUF2413 PF10310.4 CEP07032.1 - 0.19 10.5 7.7 0.19 10.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) NARP1 PF12569.3 CEP07032.1 - 0.32 9.6 7.4 0.39 9.4 5.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3807 PF12720.2 CEP07032.1 - 1.7 8.7 8.2 2.4 8.3 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PP_M1 PF03012.9 CEP07032.1 - 2.4 7.4 7.9 3.2 6.9 5.5 1.1 1 0 0 1 1 1 0 Phosphoprotein Velvet PF11754.3 CEP07033.1 - 2.3e-52 177.5 1.4 1.4e-51 174.9 1.0 2.1 1 1 0 1 1 1 1 Velvet factor DUF3859 PF12975.2 CEP07033.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Endonuclease_NS PF01223.18 CEP07034.1 - 4.8e-60 202.7 0.0 5.9e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease BAG PF02179.11 CEP07035.1 - 0.00021 21.3 2.6 0.00066 19.7 0.6 2.0 2 0 0 2 2 2 1 BAG domain DUF2408 PF10303.4 CEP07035.1 - 0.00071 19.6 3.1 0.0029 17.7 2.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) Herpes_U30 PF04523.8 CEP07035.1 - 0.016 12.7 0.1 0.024 12.1 0.1 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Val_tRNA-synt_C PF10458.4 CEP07035.1 - 0.051 13.6 2.2 3.1 7.9 0.2 2.9 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm TipAS PF07739.8 CEP07035.1 - 0.11 12.8 0.2 0.27 11.5 0.1 1.6 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain COG2 PF06148.6 CEP07035.1 - 0.11 12.3 0.3 1.7 8.4 0.1 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 CEP07035.1 - 0.12 12.1 1.8 3.7 7.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YlqD PF11068.3 CEP07035.1 - 0.16 12.0 3.0 0.26 11.2 2.0 1.5 1 1 0 1 1 1 0 YlqD protein DUF948 PF06103.6 CEP07035.1 - 0.16 11.8 1.4 1.7 8.5 0.2 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC-167 PF15188.1 CEP07035.1 - 0.19 11.6 2.0 15 5.5 0.0 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Spectrin PF00435.16 CEP07035.1 - 0.48 10.7 4.0 4.7 7.5 2.8 2.0 1 1 0 1 1 1 0 Spectrin repeat WXG100 PF06013.7 CEP07035.1 - 0.56 10.2 3.9 15 5.6 0.1 2.8 2 1 0 2 2 2 0 Proteins of 100 residues with WXG XhlA PF10779.4 CEP07035.1 - 0.79 9.6 5.2 2 8.3 1.0 2.1 1 1 1 2 2 2 0 Haemolysin XhlA tRNA-synt_2b PF00587.20 CEP07036.1 - 5.8e-35 120.4 0.0 1.1e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CEP07036.1 - 7.2e-20 71.0 11.7 7.2e-20 71.0 8.1 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain tRNA_lig_kinase PF08303.6 CEP07036.1 - 0.94 9.3 5.8 1.8 8.3 3.7 1.8 1 1 1 2 2 2 0 tRNA ligase kinase domain LMBR1 PF04791.11 CEP07036.1 - 4.6 5.7 5.1 7.2 5.0 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S8 PF00082.17 CEP07037.1 - 1.1e-98 329.8 1.5 4.2e-51 173.7 0.4 2.3 2 0 0 2 2 2 2 Subtilase family PA PF02225.17 CEP07037.1 - 5.7e-34 115.8 0.1 4.3e-16 58.4 0.0 3.0 2 0 0 2 2 2 2 PA domain DUF1034 PF06280.7 CEP07037.1 - 4.1e-16 59.3 2.1 4.1e-07 30.4 0.5 2.5 2 0 0 2 2 2 2 Fn3-like domain (DUF1034) Plus-3 PF03126.13 CEP07038.1 - 2.6e-31 107.8 2.5 3.1e-31 107.6 0.0 2.5 3 0 0 3 3 3 1 Plus-3 domain YEATS PF03366.11 CEP07038.1 - 2.6e-16 59.0 0.1 5.3e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 YEATS family Phage_Coat_A PF05357.8 CEP07038.1 - 1.1 8.8 7.3 2.9 7.5 0.0 3.6 3 0 0 3 3 3 0 Phage Coat Protein A UN_NPL4 PF11543.3 CEP07039.1 - 0.019 15.2 0.1 0.059 13.6 0.0 1.9 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBX PF00789.15 CEP07039.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 UBX domain OTU PF02338.14 CEP07039.1 - 0.12 12.9 0.0 0.82 10.2 0.0 2.3 2 1 0 2 2 2 0 OTU-like cysteine protease Homeobox PF00046.24 CEP07042.1 - 6.5e-19 67.3 0.9 1.4e-18 66.2 0.6 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP07042.1 - 0.0061 16.2 0.0 0.024 14.3 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 CEP07042.1 - 0.016 14.8 0.2 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain AAT PF03417.11 CEP07042.1 - 0.033 13.6 0.3 0.033 13.6 0.2 1.6 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SMC_Nse1 PF07574.8 CEP07043.1 - 2.1e-18 66.6 0.2 3.1e-12 46.5 0.1 2.1 2 0 0 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CEP07043.1 - 8e-06 25.7 12.6 1.3e-05 25.0 8.7 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 CEP07043.1 - 0.005 16.6 12.1 0.0082 15.9 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.1 CEP07043.1 - 0.02 14.8 3.9 0.036 14.0 2.7 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain DWNN PF08783.6 CEP07044.1 - 3e-26 91.1 0.1 4.7e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 CEP07044.1 - 9.6e-08 31.3 5.7 9.6e-08 31.3 4.0 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 CEP07044.1 - 5.1e-05 23.0 2.5 5.1e-05 23.0 1.7 2.0 2 0 0 2 2 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 CEP07044.1 - 0.0013 18.6 10.6 0.0013 18.6 7.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP07044.1 - 0.0019 17.9 10.2 0.0019 17.9 7.0 2.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP07044.1 - 0.0033 17.0 9.3 0.0033 17.0 6.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 CEP07044.1 - 0.0037 16.9 0.8 0.0037 16.9 0.5 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_4 PF15227.1 CEP07044.1 - 0.068 13.0 11.0 0.17 11.8 7.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CEP07044.1 - 0.087 12.6 4.6 0.17 11.6 3.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.10 CEP07044.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-C3HC4 PF00097.20 CEP07044.1 - 1.4 8.6 18.2 0.026 14.1 7.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CEP07044.1 - 2.6 7.7 10.7 5.6 6.6 7.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 CEP07044.1 - 3 7.6 18.0 0.29 10.8 7.8 2.4 2 1 0 2 2 2 0 zinc-RING finger domain HAD_2 PF13419.1 CEP07045.1 - 2.2e-22 80.1 0.0 3.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP07045.1 - 0.00066 20.1 0.3 0.0031 17.9 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HSP70 PF00012.15 CEP07046.1 - 9.6e-06 23.7 0.0 3.4e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CEP07046.1 - 0.077 11.5 0.0 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein Cyclin_N PF00134.18 CEP07047.1 - 5.4e-10 38.9 4.6 6.4e-07 28.9 0.2 3.8 2 2 1 3 3 3 2 Cyclin, N-terminal domain TFIIB PF00382.14 CEP07047.1 - 0.042 13.6 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat TEBP_beta PF07404.6 CEP07047.1 - 0.066 12.3 0.0 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Hist_deacetyl PF00850.14 CEP07048.1 - 4.2e-79 266.0 0.1 6.2e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Ammonium_transp PF00909.16 CEP07049.1 - 8.9e-113 376.7 30.9 1e-112 376.5 21.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Bromo_coat PF01318.13 CEP07050.1 - 0.11 12.2 0.1 0.12 12.0 0.1 1.0 1 0 0 1 1 1 0 Bromovirus coat protein PCI PF01399.22 CEP07051.1 - 6.2e-10 39.3 0.2 1.3e-09 38.2 0.2 1.6 1 0 0 1 1 1 1 PCI domain tRNA-synt_His PF13393.1 CEP07052.1 - 5.1e-41 140.7 0.0 1.6e-36 125.9 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CEP07052.1 - 1.7e-20 73.2 0.0 3.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Usp PF00582.21 CEP07052.1 - 1.9e-16 60.5 0.0 6.8e-16 58.7 0.0 2.1 1 0 0 1 1 1 1 Universal stress protein family WHEP-TRS PF00458.15 CEP07052.1 - 8.4e-15 54.1 6.3 2.8e-14 52.5 4.4 2.0 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon PF03129.15 CEP07052.1 - 1.4e-12 47.3 0.4 1.4e-11 44.2 0.1 2.6 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CEP07052.1 - 6.2e-05 21.9 0.1 0.0043 15.8 0.1 2.8 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) RRM_1 PF00076.17 CEP07053.1 - 4.4e-09 35.8 0.1 7.2e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07053.1 - 1.1e-07 31.6 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07053.1 - 1.1e-05 25.2 0.9 1.7e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP07053.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CEP07053.1 - 0.003 17.3 0.1 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif zf-CCCH_2 PF14608.1 CEP07053.1 - 0.0048 16.8 2.8 0.0048 16.8 1.9 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type FYVE PF01363.16 CEP07053.1 - 0.011 15.6 1.3 0.015 15.1 0.2 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH PF00642.19 CEP07053.1 - 0.016 14.8 2.1 0.016 14.8 1.4 2.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glyco_transf_15 PF01793.11 CEP07054.1 - 5.6e-137 456.1 9.8 6.6e-137 455.8 6.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Choline_transpo PF04515.7 CEP07056.1 - 5.4e-81 271.9 32.8 5.4e-81 271.9 22.7 2.1 2 1 0 2 2 2 1 Plasma-membrane choline transporter Zn_clus PF00172.13 CEP07056.1 - 2.9e-08 33.4 9.8 4.8e-08 32.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF159 PF02586.9 CEP07057.1 - 2.7e-40 138.1 0.0 1.4e-22 80.2 0.0 2.2 1 1 1 2 2 2 2 Uncharacterised ACR, COG2135 Nup188 PF10487.4 CEP07058.1 - 1.7e-27 95.8 12.7 1.7e-27 95.8 8.8 2.5 2 1 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Phage_int_SAM_5 PF13102.1 CEP07058.1 - 0.13 12.2 2.4 0.18 11.7 0.4 2.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain DUF840 PF05801.6 CEP07061.1 - 0.13 12.4 0.2 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) UQ_con PF00179.21 CEP07062.1 - 1.2e-31 108.9 0.3 2.5e-31 107.9 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Abhydrolase_8 PF06259.7 CEP07062.1 - 0.034 13.6 0.2 0.073 12.5 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Myb_DNA-bind_6 PF13921.1 CEP07063.1 - 5.6e-08 32.7 2.4 4.6e-06 26.6 0.0 4.6 4 1 2 6 6 6 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP07063.1 - 1.4e-06 28.2 0.6 0.012 15.6 0.0 3.4 2 1 0 2 2 2 2 Myb-like DNA-binding domain Bromodomain PF00439.20 CEP07064.1 - 3.9e-19 68.3 0.4 9.7e-19 67.0 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CEP07064.1 - 6.3e-08 32.6 0.1 1.4e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP07064.1 - 8.8e-07 28.8 0.1 4e-06 26.7 0.0 2.2 2 1 1 3 3 3 1 Acetyltransferase (GNAT) family Prothymosin PF03247.9 CEP07064.1 - 0.014 15.5 5.6 0.014 15.5 3.8 5.3 2 1 1 3 3 3 0 Prothymosin/parathymosin family Peptidase_M19 PF01244.16 CEP07066.1 - 4.6e-112 374.0 0.0 5.4e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RRM_1 PF00076.17 CEP07067.1 - 7.2e-39 131.2 0.3 2.3e-18 65.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07067.1 - 1.4e-34 117.8 0.1 4.7e-17 61.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07067.1 - 1.8e-12 46.9 0.0 1.2e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 CEP07067.1 - 0.0015 18.5 29.0 0.0015 18.5 20.1 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Nup35_RRM_2 PF14605.1 CEP07067.1 - 0.046 13.5 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MCM_N PF14551.1 CEP07067.1 - 0.97 9.9 8.1 1.1 9.7 4.2 2.1 2 0 0 2 2 2 0 MCM N-terminal domain Tubulin PF00091.20 CEP07068.1 - 4.4e-63 212.9 0.0 9.1e-63 211.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEP07068.1 - 1.5e-47 160.7 0.0 2.3e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain RE_EcoO109I PF14511.1 CEP07068.1 - 0.056 12.8 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I DUF3008 PF11450.3 CEP07069.1 - 0.029 14.5 1.0 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Myc_target_1 PF15179.1 CEP07069.1 - 0.049 13.2 0.6 0.057 13.0 0.4 1.1 1 0 0 1 1 1 0 Myc target protein 1 CGGC PF08821.6 CEP07070.1 - 0.014 15.4 3.4 0.031 14.3 1.9 1.9 1 1 1 2 2 2 0 CGGC domain DUF2877 PF11392.3 CEP07070.1 - 0.16 12.2 0.2 0.72 10.0 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2877) Baculo_LEF5_C PF11792.3 CEP07070.1 - 0.89 8.9 3.9 0.24 10.8 0.2 1.9 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain PAP_central PF04928.12 CEP07071.1 - 0.017 13.9 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain RapA_C PF12137.3 CEP07071.1 - 0.028 13.2 0.4 0.048 12.4 0.2 1.6 1 1 0 1 1 1 0 RNA polymerase recycling family C-terminal Streptin-Immun PF11083.3 CEP07071.1 - 0.034 14.1 0.3 0.052 13.5 0.2 1.4 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein FlaC_arch PF05377.6 CEP07071.1 - 0.052 13.4 1.1 1.7 8.6 0.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF3713 PF12506.3 CEP07071.1 - 0.069 13.2 0.8 0.079 13.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) SOR PF07682.6 CEP07071.1 - 0.12 10.8 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Sulphur oxygenase reductase DUF2789 PF10982.3 CEP07071.1 - 0.22 11.5 1.3 0.37 10.8 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2789) HMG_box PF00505.14 CEP07073.1 - 1e-36 125.0 3.2 2e-17 63.2 0.1 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP07073.1 - 1.6e-29 102.0 1.4 2.2e-13 50.3 0.1 2.7 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.1 CEP07073.1 - 0.013 15.2 0.7 0.013 15.2 0.5 2.2 2 1 0 2 2 2 0 HMG (high mobility group) box 5 Pkinase PF00069.20 CEP07074.1 - 1.1e-32 113.2 0.0 1.6e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Metallophos PF00149.23 CEP07074.1 - 1.3e-11 44.3 0.3 2.3e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase_Tyr PF07714.12 CEP07074.1 - 2.2e-10 40.0 0.0 3.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CEP07074.1 - 0.036 13.4 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M20 PF01546.23 CEP07075.1 - 1.2e-31 109.6 0.0 1.9e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CEP07075.1 - 4.6e-13 48.8 0.0 8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CEP07075.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Bromodomain PF00439.20 CEP07076.1 - 4e-18 65.1 0.0 1.3e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.20 CEP07076.1 - 1.1e-14 54.2 3.9 1.2e-07 31.1 0.4 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07076.1 - 5.5e-08 32.1 0.9 0.0065 15.5 0.5 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CEP07076.1 - 0.038 13.0 0.1 0.12 11.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.22 CEP07078.1 - 4.2e-15 55.6 0.1 5.3e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sec7 PF01369.15 CEP07079.1 - 5.2e-38 130.6 1.1 1.2e-37 129.4 0.8 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CEP07079.1 - 1e-23 83.7 0.1 3.1e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEP07079.1 - 1.4e-05 25.2 0.2 9.7e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 PH domain PIF1 PF05970.9 CEP07080.1 - 6.9e-14 51.5 0.0 7.9e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase HTH_Tnp_1 PF01527.15 CEP07081.1 - 1e-05 25.3 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.10 CEP07081.1 - 6.6e-05 22.6 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 CEP07081.1 - 0.00016 21.1 0.0 0.00032 20.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP07081.1 - 0.00032 20.6 0.0 0.00068 19.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP07081.1 - 0.0035 17.4 0.0 0.051 13.7 0.0 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_IclR PF09339.5 CEP07081.1 - 0.0079 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF1836 PF08876.6 CEP07081.1 - 0.0087 15.7 0.2 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1836) HTH_psq PF05225.11 CEP07081.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain TrmB PF01978.14 CEP07081.1 - 0.043 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.7 CEP07081.1 - 0.067 12.6 0.0 0.26 10.8 0.0 2.0 1 1 1 2 2 2 0 Sigma-70, region 4 Chromo PF00385.19 CEP07084.1 - 4.8e-09 35.7 0.3 7.8e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 CEP07084.1 - 0.0058 16.5 0.1 0.0097 15.7 0.1 1.3 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 GCR1_C PF12550.3 CEP07085.1 - 3.2e-22 78.1 3.6 5.4e-22 77.4 2.5 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_5 PF08360.6 CEP07085.1 - 0.00096 19.1 0.8 0.00096 19.1 0.6 1.5 2 0 0 2 2 2 1 QacR-like protein, C-terminal region rve PF00665.21 CEP07086.1 - 3.4e-18 65.9 0.0 6.2e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP07086.1 - 0.00029 20.1 0.3 0.00067 19.0 0.2 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger zf-UBR PF02207.15 CEP07087.1 - 1.6e-19 69.3 10.1 4e-19 68.0 7.0 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CEP07087.1 - 5.6e-09 35.6 0.0 1.7e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS F-box-like PF12937.2 CEP07088.1 - 2.7e-08 33.4 0.3 7.3e-08 32.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP07088.1 - 4.8e-07 29.2 0.4 1.1e-06 28.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain SopA PF13981.1 CEP07088.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 SopA-like central domain Det1 PF09737.4 CEP07089.1 - 5.5 5.6 7.3 8.8 4.9 5.1 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 rve PF00665.21 CEP07090.1 - 1.1e-16 61.0 0.0 2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP07090.1 - 2.2e-06 26.9 0.0 4.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 CEP07090.1 - 0.0023 17.4 0.0 0.006 16.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Glyco_transf_90 PF05686.7 CEP07090.1 - 0.0049 15.6 0.0 1.8 7.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 90 DUF365 PF04033.7 CEP07090.1 - 0.057 13.4 0.3 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF365) RVT_1 PF00078.22 CEP07091.1 - 1.4e-12 47.4 0.2 4.1e-10 39.3 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP07091.1 - 0.0016 18.8 0.0 0.0051 17.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP07091.1 - 0.0048 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease VPR PF00522.13 CEP07092.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 VPR/VPX protein DUF2303 PF10065.4 CEP07092.1 - 0.15 10.9 0.2 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) RVT_1 PF00078.22 CEP07094.1 - 1.6e-25 89.7 0.0 1.9e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HDC PF02329.11 CEP07094.1 - 0.065 11.8 0.0 0.21 10.2 0.0 1.7 2 0 0 2 2 2 0 Histidine carboxylase PI chain Helitron_like_N PF14214.1 CEP07095.1 - 1e-23 84.0 0.6 1.7e-23 83.2 0.4 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 CEP07095.1 - 0.011 15.3 0.8 0.088 12.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3296) InvH PF04741.7 CEP07097.1 - 0.048 13.4 0.7 0.066 13.0 0.5 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein RPW8 PF05659.6 CEP07099.1 - 0.029 13.9 0.2 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 dCMP_cyt_deam_1 PF00383.17 CEP07100.1 - 1.4e-10 40.6 0.0 2.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CEP07100.1 - 0.0095 15.7 0.3 0.084 12.7 0.2 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase zf-met PF12874.2 CEP07101.1 - 6e-24 83.4 93.9 0.00094 19.2 1.4 15.6 16 0 0 16 16 16 9 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CEP07101.1 - 4e-19 68.5 58.9 0.0017 18.3 0.1 11.7 3 3 11 14 14 14 13 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CEP07101.1 - 1.6e-16 59.8 106.5 0.0078 16.3 1.7 14.9 16 0 0 16 16 16 10 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 CEP07101.1 - 2.5e-06 26.3 69.1 0.079 11.4 0.8 13.9 14 1 1 15 15 15 7 Protein of unknown function (DUF629) Ribosomal_L31 PF01197.13 CEP07101.1 - 0.00013 21.8 6.8 21 5.2 0.0 7.8 8 0 0 8 8 8 0 Ribosomal protein L31 zf-AD PF07776.10 CEP07101.1 - 0.00026 20.9 29.1 0.82 9.7 0.1 9.1 8 1 2 10 10 10 3 Zinc-finger associated domain (zf-AD) zf-C2H2_6 PF13912.1 CEP07101.1 - 0.19 11.6 0.1 0.19 11.6 0.1 14.4 16 0 0 16 16 16 0 C2H2-type zinc finger Trm112p PF03966.11 CEP07101.1 - 0.28 11.5 22.1 2.4 8.6 0.0 7.8 9 2 0 9 9 9 0 Trm112p-like protein Peptidase_M16_C PF05193.16 CEP07102.1 - 1e-27 97.0 0.0 4e-18 65.7 0.0 3.2 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CEP07102.1 - 2.7e-09 36.9 1.0 1.6e-05 24.6 0.0 3.4 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 CEP07102.1 - 1.3 7.8 10.8 2 7.2 0.1 3.2 3 1 0 3 3 3 0 Peptidase M16C associated Tctex-1 PF03645.8 CEP07103.1 - 1e-28 99.1 2.2 1.3e-28 98.8 1.6 1.2 1 0 0 1 1 1 1 Tctex-1 family Interferon PF00143.14 CEP07103.1 - 0.0013 18.6 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Interferon alpha/beta domain INTS5_N PF14837.1 CEP07103.1 - 0.067 12.5 0.3 0.091 12.1 0.2 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus DUF1140 PF06600.6 CEP07103.1 - 0.087 12.9 0.8 1.6 8.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1140) zf-RVT PF13966.1 CEP07107.1 - 0.0048 17.1 0.1 0.0099 16.1 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exc PF07825.6 CEP07107.1 - 0.034 13.9 0.6 0.058 13.1 0.4 1.4 1 0 0 1 1 1 0 Excisionase-like protein UCR_6-4kD PF08997.5 CEP07107.1 - 0.039 13.6 0.2 0.078 12.6 0.2 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DDE_3 PF13358.1 CEP07108.1 - 5.5e-19 68.3 0.1 6.1e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP07108.1 - 0.0031 17.5 0.0 0.0038 17.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 CEP07108.1 - 0.067 12.3 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease AKAP95 PF04988.7 CEP07109.1 - 0.031 14.0 1.1 0.64 9.7 0.2 2.3 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Acyl_transf_1 PF00698.16 CEP07111.1 - 2.1e-66 224.4 0.0 2.6e-65 220.8 0.0 2.5 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CEP07111.1 - 1.1e-31 108.7 0.1 2.8e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 CEP07111.1 - 4.1e-29 100.1 0.3 4.1e-29 100.1 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) ketoacyl-synt PF00109.21 CEP07111.1 - 5.7e-20 71.8 0.1 1.5e-19 70.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 CEP07111.1 - 6.7e-17 61.3 0.0 1.6e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.1 CEP07111.1 - 6.1e-15 55.1 0.0 6.1e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Ketoacyl-synt_C PF02801.17 CEP07111.1 - 4.7e-10 39.3 0.0 1.5e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Pkinase PF00069.20 CEP07112.1 - 1e-37 129.7 0.5 3e-37 128.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07112.1 - 2.4e-21 75.9 1.1 7.9e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP07112.1 - 4.5e-08 32.3 0.0 1.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like CRT10 PF08728.5 CEP07112.1 - 0.16 9.9 13.9 0.26 9.2 9.6 1.2 1 0 0 1 1 1 0 CRT10 DDE_3 PF13358.1 CEP07115.1 - 8.1e-22 77.5 0.0 9.7e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP07115.1 - 0.00078 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF4240 PF14024.1 CEP07115.1 - 0.034 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) DDE_1 PF03184.14 CEP07115.1 - 0.052 12.6 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease rve PF00665.21 CEP07116.1 - 3.7e-21 75.4 0.0 9.8e-21 74.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CEP07116.1 - 1.3e-07 32.0 0.1 6.8e-07 29.7 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP07116.1 - 8.3e-07 28.7 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 CEP07116.1 - 1.2e-05 24.7 0.1 0.00033 20.0 0.0 2.8 1 1 2 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CEP07116.1 - 0.00014 21.6 6.9 0.00027 20.7 4.8 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 CEP07116.1 - 0.00016 21.5 0.1 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.1 CEP07116.1 - 0.00075 18.9 0.0 0.0042 16.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVP PF00077.15 CEP07116.1 - 0.012 15.4 0.8 0.039 13.8 0.1 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 CEP07116.1 - 0.79 9.4 2.9 3.8 7.2 1.7 2.3 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.21 CEP07117.1 - 1.4e-21 76.7 0.0 2.5e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP07117.1 - 0.0008 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_2 PF02914.10 CEP07117.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase zinc_ribbon_6 PF14599.1 CEP07118.1 - 0.36 10.6 2.6 8.5 6.2 0.0 3.1 2 1 1 3 3 3 0 Zinc-ribbon RasGEF PF00617.14 CEP07119.1 - 1.5e-63 213.9 0.4 3.9e-63 212.5 0.3 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEP07119.1 - 1.3e-24 86.3 1.3 4.5e-24 84.5 0.9 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.21 CEP07119.1 - 6.5e-09 35.4 3.6 1.5e-08 34.3 2.5 1.6 1 0 0 1 1 1 1 WW domain Talin_middle PF09141.5 CEP07119.1 - 0.039 13.6 3.0 2.9 7.5 0.0 3.1 1 1 1 2 2 2 0 Talin, middle domain Exo_endo_phos_2 PF14529.1 CEP07120.1 - 2.1e-13 49.9 0.3 3.6e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP07120.1 - 2e-06 27.9 0.9 2e-06 27.9 0.6 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Mononeg_mRNAcap PF14318.1 CEP07121.1 - 5.7e-10 38.6 0.0 9.3e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Mononegavirales mRNA-capping region V RVT_1 PF00078.22 CEP07122.1 - 9.6e-24 83.9 0.4 2.1e-23 82.8 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 CEP07122.1 - 3.2e-09 36.4 0.1 6.5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CEP07122.1 - 2.7e-08 34.2 0.1 5.8e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP07122.1 - 7.4e-07 29.0 0.3 2e-06 27.6 0.2 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A3 PF02160.10 CEP07122.1 - 2.7e-05 23.8 0.6 2.7e-05 23.8 0.4 1.9 2 0 0 2 2 2 1 Cauliflower mosaic virus peptidase (A3) RVP_2 PF08284.6 CEP07122.1 - 4e-05 23.5 0.0 8.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP07122.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CEP07122.1 - 0.052 12.8 1.0 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 Ty3 transposon peptidase SWIB PF02201.13 CEP07123.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 SWIB/MDM2 domain zf-MIZ PF02891.15 CEP07124.1 - 5.7e-19 67.3 2.6 1.1e-18 66.3 1.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CEP07124.1 - 1.9e-05 24.0 1.4 4.6e-05 22.8 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RestrictionMunI PF11407.3 CEP07125.1 - 0.098 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II restriction enzyme MunI Phosphodiest PF01663.17 CEP07126.1 - 8.4e-68 229.3 2.9 4.4e-66 223.6 2.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Epiglycanin_TR PF05647.6 CEP07127.1 - 0.046 13.5 4.2 0.086 12.6 2.9 1.4 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Methyltransf_23 PF13489.1 CEP07129.1 - 3.4e-13 49.6 0.0 6.1e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP07129.1 - 1.5e-12 47.8 0.0 3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP07129.1 - 5.5e-10 39.0 0.0 2.4e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP07129.1 - 2.3e-09 37.5 0.0 6.6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP07129.1 - 2.4e-09 36.5 0.0 1.9e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEP07129.1 - 3.8e-08 33.8 0.0 2.1e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP07129.1 - 2.9e-07 30.8 0.0 6.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP07129.1 - 0.0002 21.3 0.0 0.0024 17.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP07129.1 - 0.00054 19.1 0.0 0.0013 17.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 CEP07129.1 - 0.0021 17.7 0.0 0.007 16.0 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 CEP07129.1 - 0.0078 15.6 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.7 CEP07129.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CheR PF01739.13 CEP07129.1 - 0.02 14.1 0.0 7.2 5.8 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 CEP07129.1 - 0.028 14.4 0.0 0.07 13.1 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 CEP07129.1 - 0.034 12.8 0.1 0.074 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PCMT PF01135.14 CEP07129.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.17 CEP07130.1 - 1.1e-14 53.7 0.0 1.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07130.1 - 4e-10 39.5 0.0 6.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07130.1 - 3.1e-09 36.5 0.0 4.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 CEP07130.1 - 9.1e-09 34.8 4.1 1.5e-08 34.1 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CEP07130.1 - 0.16 11.7 2.2 0.31 10.8 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1777 PF08648.7 CEP07130.1 - 2.1 8.0 29.7 3 7.5 20.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF566 PF04484.7 CEP07130.1 - 4.4 6.7 9.3 4.9 6.5 6.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) RPA PF10134.4 CEP07131.1 - 0.084 12.1 0.1 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Replication initiator protein A tRNA-synt_2b PF00587.20 CEP07132.1 - 1.5e-67 226.5 0.2 2.2e-67 225.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEP07132.1 - 7.3e-21 73.9 0.0 2.5e-20 72.1 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain zf-C2HC5 PF06221.8 CEP07133.1 - 3.7e-23 81.0 6.2 6.7e-23 80.2 4.3 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF2870 PF11069.3 CEP07133.1 - 0.32 11.0 0.0 0.32 11.0 0.0 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ribosomal_L22 PF00237.14 CEP07135.1 - 1.1e-33 115.3 0.1 1.5e-33 114.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4570 PF15134.1 CEP07137.1 - 0.44 10.4 6.0 0.18 11.6 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) Kunitz_BPTI PF00014.18 CEP07138.1 - 3 8.1 6.1 1.1 9.4 0.5 2.3 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain CHU_C PF13585.1 CEP07139.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Corona_6B_7B PF03262.8 CEP07139.1 - 0.13 11.4 0.0 0.26 10.5 0.0 1.3 1 1 0 1 1 1 0 Coronavirus 6B/7B protein GATA PF00320.22 CEP07140.1 - 7.4e-17 60.4 4.7 7.4e-17 60.4 3.2 1.9 2 0 0 2 2 2 1 GATA zinc finger Cut8_N PF14482.1 CEP07140.1 - 0.0029 17.5 1.0 0.0029 17.5 0.7 2.6 2 1 0 2 2 2 1 Cut8 proteasome-binding domain GSu_C4xC__C2xCH PF09698.5 CEP07140.1 - 0.28 11.3 4.8 0.63 10.2 3.3 1.5 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) CDC45 PF02724.9 CEP07140.1 - 3.1 5.7 15.4 5 5.0 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 CEP07140.1 - 8.7 5.8 11.8 16 5.0 8.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin Peptidase_M41 PF01434.13 CEP07141.1 - 8.5e-76 254.1 2.1 1.6e-75 253.2 1.5 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CEP07141.1 - 2.5e-43 147.4 0.0 1.1e-42 145.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEP07141.1 - 1.5e-06 27.9 0.0 4.6e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CEP07141.1 - 5.6e-06 26.5 1.4 0.0099 16.0 0.0 4.0 3 1 0 4 4 3 1 AAA domain TIP49 PF06068.8 CEP07141.1 - 1.3e-05 24.1 0.2 4.3e-05 22.4 0.0 1.9 3 0 0 3 3 3 1 TIP49 C-terminus AAA_17 PF13207.1 CEP07141.1 - 2.2e-05 25.2 0.0 0.00013 22.7 0.0 2.3 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CEP07141.1 - 9.6e-05 21.5 0.0 0.00027 20.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CEP07141.1 - 0.00011 22.1 0.0 0.00063 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CEP07141.1 - 0.00017 21.2 0.6 0.00062 19.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CEP07141.1 - 0.00034 20.6 0.8 0.0032 17.4 0.1 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CEP07141.1 - 0.00051 19.9 0.1 0.0066 16.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 CEP07141.1 - 0.00089 18.2 0.0 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 CEP07141.1 - 0.001 18.4 0.9 0.075 12.4 0.2 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CEP07141.1 - 0.0018 17.7 0.1 0.0046 16.3 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 CEP07141.1 - 0.0036 17.2 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CEP07141.1 - 0.0039 16.3 0.3 0.01 15.0 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CEP07141.1 - 0.004 16.2 0.3 0.014 14.5 0.1 2.0 1 1 1 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CEP07141.1 - 0.013 15.3 0.2 0.052 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CEP07141.1 - 0.014 14.8 0.1 0.29 10.5 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 CEP07141.1 - 0.017 15.4 0.0 0.064 13.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 CEP07141.1 - 0.019 14.6 0.2 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 CEP07141.1 - 0.027 14.5 0.4 0.19 11.7 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain KaiC PF06745.8 CEP07141.1 - 0.029 13.4 2.9 0.66 9.0 0.0 3.7 4 1 1 5 5 5 0 KaiC AAA_11 PF13086.1 CEP07141.1 - 0.35 10.3 2.7 2.4 7.6 0.0 2.9 3 1 1 4 4 3 0 AAA domain Apolipoprotein PF01442.13 CEP07142.1 - 0.0023 17.4 12.1 0.016 14.7 8.4 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain MCPVI PF02993.9 CEP07142.1 - 0.12 12.4 7.5 0.2 11.7 5.2 1.4 1 0 0 1 1 1 0 Minor capsid protein VI DUF3708 PF12501.3 CEP07142.1 - 0.2 11.5 7.6 0.21 11.4 0.3 2.4 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter DUF3818 PF12825.2 CEP07142.1 - 0.96 8.0 7.3 1.2 7.7 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) KMP11 PF03037.11 CEP07142.1 - 1.2 9.8 6.7 4.2 8.0 3.0 2.3 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 DUF883 PF05957.8 CEP07142.1 - 3.1 8.2 23.1 1.8 9.0 1.8 3.4 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) BssC_TutF PF08201.6 CEP07142.1 - 3.6 7.1 15.0 1.6 8.2 1.6 3.1 1 1 3 4 4 4 0 BssC/TutF protein HR1 PF02185.11 CEP07142.1 - 7.7 6.3 8.6 0.44 10.3 1.5 2.1 2 1 0 2 2 2 0 Hr1 repeat DSX_dimer PF08828.5 CEP07142.1 - 8.7 5.9 7.9 1.6 8.3 0.2 3.0 2 2 2 4 4 4 0 Doublesex dimerisation domain MFS_1 PF07690.11 CEP07143.1 - 3.4e-16 58.9 32.9 3.4e-16 58.9 22.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF983 PF06170.7 CEP07143.1 - 0.029 14.4 11.8 0.065 13.3 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF983) UPF1_Zn_bind PF09416.5 CEP07144.1 - 1.2e-74 248.9 6.0 1.2e-74 248.9 4.2 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CEP07144.1 - 1.8e-57 193.9 0.0 3.5e-57 193.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEP07144.1 - 2e-55 187.9 1.8 3.2e-55 187.2 1.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP07144.1 - 1.2e-14 53.7 0.1 3.6e-14 52.2 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 CEP07144.1 - 7.5e-13 48.4 0.1 9.8e-12 44.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CEP07144.1 - 6.3e-08 32.6 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 CEP07144.1 - 1.3e-05 24.8 0.0 0.26 10.7 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CEP07144.1 - 2.8e-05 23.2 0.5 0.00037 19.5 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 CEP07144.1 - 0.00044 19.9 0.0 0.00097 18.8 0.0 1.7 1 1 0 1 1 1 1 Helicase DEAD PF00270.24 CEP07144.1 - 0.0014 18.1 0.1 0.0058 16.1 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SRP54 PF00448.17 CEP07144.1 - 0.0067 15.8 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CEP07144.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ribosomal_S13_N PF08069.7 CEP07144.1 - 0.025 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 CEP07144.1 - 0.027 14.5 0.0 0.073 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CEP07144.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain ArsA_ATPase PF02374.10 CEP07144.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_16 PF13191.1 CEP07144.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 CEP07144.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CEP07144.1 - 0.15 11.1 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 CEP07144.1 - 0.17 11.1 0.0 0.4 9.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Apc4 PF12896.2 CEP07146.1 - 4.3e-23 81.7 2.7 7.5e-23 80.9 1.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Kinesin PF00225.18 CEP07147.1 - 3.9e-77 259.2 0.0 3.9e-77 259.2 0.0 2.9 4 0 0 4 4 4 1 Kinesin motor domain Phage_int_SAM_4 PF13495.1 CEP07148.1 - 0.0012 19.1 0.4 0.0022 18.2 0.3 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 CEP07148.1 - 0.015 15.4 0.9 0.015 15.4 0.6 1.8 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Cut8_C PF08559.5 CEP07149.1 - 3.5e-24 85.2 0.1 6.5e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Cut8 six-helix bundle RE_ScaI PF09569.5 CEP07149.1 - 0.014 14.8 0.1 0.033 13.6 0.1 1.6 1 1 0 1 1 1 0 ScaI restriction endonuclease NatB_MDM20 PF09797.4 CEP07149.1 - 0.049 12.3 1.0 0.61 8.7 0.1 2.1 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit Aminotran_4 PF01063.14 CEP07150.1 - 3.5e-25 88.8 0.0 4.3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV MRP_L53 PF10780.4 CEP07151.1 - 1.6e-08 34.3 0.1 2.6e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 POLO_box PF00659.13 CEP07151.1 - 0.038 13.9 0.0 0.27 11.2 0.0 2.0 1 1 1 2 2 2 0 POLO box duplicated region S-methyl_trans PF02574.11 CEP07152.1 - 5.4e-91 305.0 0.0 1.5e-90 303.6 0.0 1.7 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 CEP07152.1 - 3.8e-74 248.4 0.0 7e-74 247.5 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 CEP07152.1 - 2.7e-42 144.5 0.1 1e-41 142.6 0.1 2.1 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding PF02310.14 CEP07152.1 - 4.2e-18 65.3 0.7 6.7e-17 61.4 0.2 3.0 3 0 0 3 3 3 1 B12 binding domain B12-binding_2 PF02607.12 CEP07152.1 - 6.3e-18 64.5 0.1 1.1e-16 60.6 0.0 2.9 2 0 0 2 2 2 1 B12 binding domain VID27 PF08553.5 CEP07153.1 - 0.013 13.7 19.7 0.012 13.8 13.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 CEP07153.1 - 0.019 13.4 30.8 0.022 13.2 21.3 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CEP07153.1 - 0.027 12.4 33.6 0.029 12.2 23.3 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 CEP07153.1 - 0.036 13.1 28.8 0.04 13.0 20.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.8 CEP07153.1 - 0.037 12.7 20.8 0.039 12.6 14.4 1.2 1 0 0 1 1 1 0 Paf1 MYCBPAP PF14646.1 CEP07153.1 - 0.081 11.6 12.1 0.097 11.3 8.4 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family TFIIA PF03153.8 CEP07153.1 - 0.094 12.5 27.7 0.11 12.3 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 CEP07153.1 - 0.11 11.6 14.8 0.12 11.6 10.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SprA-related PF12118.3 CEP07153.1 - 0.2 10.9 11.9 0.24 10.6 8.3 1.1 1 0 0 1 1 1 0 SprA-related family DDHD PF02862.12 CEP07153.1 - 0.59 9.8 8.8 0.8 9.4 6.1 1.2 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.5 CEP07153.1 - 1.1 8.2 24.2 1.3 8.0 16.8 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.3 CEP07153.1 - 1.2 7.6 9.0 1.3 7.4 6.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Raftlin PF15250.1 CEP07153.1 - 1.2 7.5 7.4 1.4 7.3 5.1 1.1 1 0 0 1 1 1 0 Raftlin TFIIF_alpha PF05793.7 CEP07153.1 - 2.2 6.5 27.9 2.2 6.5 19.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.7 CEP07153.1 - 2.3 8.0 16.0 2.8 7.7 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.6 CEP07153.1 - 3 5.8 18.2 3.1 5.7 12.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 CEP07153.1 - 3.3 5.6 27.0 4.7 5.1 18.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 CEP07153.1 - 4.6 6.1 5.8 4.5 6.1 4.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Prog_receptor PF02161.10 CEP07153.1 - 4.8 5.8 11.1 4.8 5.8 7.7 1.2 1 0 0 1 1 1 0 Progesterone receptor Ycf1 PF05758.7 CEP07153.1 - 8.1 4.0 12.8 8.7 3.9 8.9 1.2 1 0 0 1 1 1 0 Ycf1 Pilt PF15453.1 CEP07153.1 - 8.6 5.9 11.7 10 5.7 8.1 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Phage_integrase PF00589.17 CEP07154.1 - 0.00072 19.2 0.1 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family Mg_chelatase PF01078.16 CEP07154.1 - 0.096 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.9 CEP07156.1 - 5.6e-11 41.9 0.0 6.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase rve PF00665.21 CEP07157.1 - 9.6e-20 70.8 0.0 1.8e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP07157.1 - 1.5e-16 59.8 2.3 4.9e-16 58.1 1.6 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP07157.1 - 0.00053 19.3 0.3 0.0011 18.3 0.2 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve PF00665.21 CEP07159.1 - 6.6e-09 35.9 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP07159.1 - 1.4e-06 27.6 0.0 2.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain OSTMP1 PF09777.4 CEP07159.1 - 0.052 12.7 0.2 0.81 8.8 0.0 2.0 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor FlxA PF14282.1 CEP07161.1 - 0.14 12.1 2.2 0.11 12.4 0.5 1.5 2 0 0 2 2 2 0 FlxA-like protein M_domain PF12938.2 CEP07161.1 - 0.25 11.0 2.0 1 9.1 0.4 2.0 2 0 0 2 2 2 0 M domain of GW182 Ketoacyl-synt_C PF02801.17 CEP07162.1 - 1.4e-32 112.0 0.6 2.2e-32 111.3 0.4 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 CEP07162.1 - 7e-27 94.5 1.7 1.4e-26 93.4 0.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 CEP07162.1 - 3.1e-06 26.3 0.0 4.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEP07162.1 - 0.00032 20.0 3.0 0.0033 16.8 0.1 2.6 2 1 0 2 2 2 1 Thiolase, C-terminal domain Haem_oxygenas_2 PF14518.1 CEP07162.1 - 0.042 14.0 0.0 2.5 8.3 0.0 2.7 3 0 0 3 3 3 0 Iron-containing redox enzyme ACP_syn_III PF08545.5 CEP07162.1 - 0.091 12.4 1.8 2.9 7.5 0.0 2.8 3 1 1 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 CEP07163.1 - 2e-18 66.8 0.1 2.1e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain RVT_1 PF00078.22 CEP07164.1 - 0.00026 20.4 0.0 0.0021 17.4 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP07165.1 - 9.4e-24 83.9 0.0 1.6e-23 83.2 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neuroparsin PF07327.6 CEP07165.1 - 0.061 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Neuroparsin Patched PF02460.13 CEP07167.1 - 1.8e-83 280.9 11.0 2.7e-49 167.8 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CEP07167.1 - 7.3e-49 165.1 6.8 7.3e-49 165.1 4.7 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 CEP07167.1 - 0.00015 20.6 4.9 0.00015 20.6 3.4 2.5 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.14 CEP07167.1 - 0.051 10.9 17.4 0.099 10.0 12.0 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF2207 PF09972.4 CEP07167.1 - 4.1 5.8 5.4 4.4 5.7 1.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PRP38 PF03371.10 CEP07168.1 - 4.2e-64 215.3 0.3 5.2e-64 215.0 0.2 1.0 1 0 0 1 1 1 1 PRP38 family RNA_pol_3_Rpc31 PF11705.3 CEP07169.1 - 5.6 6.8 14.0 8.5 6.2 9.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 zf-CCHC PF00098.18 CEP07170.1 - 0.0079 16.0 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle HECT PF00632.20 CEP07173.1 - 4.2e-97 325.0 0.0 9e-97 324.0 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 CEP07173.1 - 2.7e-81 273.2 3.4 2.7e-81 273.2 2.4 5.2 7 0 0 7 7 7 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 CEP07173.1 - 1.1e-58 199.1 4.3 1.1e-58 199.1 3.0 4.6 3 1 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 CEP07173.1 - 7.1e-18 64.5 4.0 7.1e-18 64.5 2.7 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4414) UBA PF00627.26 CEP07173.1 - 1.7e-08 34.0 0.2 6e-08 32.3 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain RhoGAP PF00620.22 CEP07174.1 - 2e-34 118.3 0.0 3.7e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain ATP-synt_E PF05680.7 CEP07175.1 - 1e-16 60.6 0.2 1.9e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 ATP synthase E chain RhoGAP PF00620.22 CEP07176.1 - 8.9e-45 152.0 0.4 2.4e-44 150.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CEP07176.1 - 4.3e-12 46.0 0.5 4.6e-11 42.7 0.0 2.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Apt1 PF10351.4 CEP07177.1 - 1.5e-104 350.4 1.4 1.5e-104 350.4 1.0 4.2 5 1 0 5 5 5 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 CEP07177.1 - 4.6e-81 272.6 5.2 4.6e-81 272.6 3.6 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 CEP07177.1 - 7.2e-37 126.7 0.0 2.5e-36 124.9 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CEP07177.1 - 2.5e-28 98.8 0.2 8.6e-28 97.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CEP07177.1 - 3.2e-15 56.4 5.5 4e-14 52.8 2.3 3.8 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain AalphaY_MDB PF04611.7 CEP07178.1 - 0.013 15.3 0.2 0.027 14.3 0.2 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region TFIID-31kDa PF02291.10 CEP07178.1 - 0.082 12.6 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FYVE PF01363.16 CEP07180.1 - 2.8e-20 71.9 8.1 2.8e-20 71.9 5.6 3.0 3 0 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.11 CEP07180.1 - 0.0086 15.9 9.3 0.078 12.8 6.3 2.4 1 1 1 2 2 2 1 FYVE-type zinc finger zf-RING_5 PF14634.1 CEP07180.1 - 0.099 12.3 16.2 4.2 7.1 7.1 3.6 3 1 0 3 3 3 0 zinc-RING finger domain GKAP PF03359.8 CEP07180.1 - 0.14 11.7 10.3 0.22 11.1 7.1 1.3 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein zf-RING_2 PF13639.1 CEP07180.1 - 0.91 9.4 0.0 0.91 9.4 0.0 3.6 2 1 0 2 2 2 0 Ring finger domain BUD22 PF09073.5 CEP07180.1 - 0.97 8.4 10.8 1.5 7.7 7.5 1.3 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.10 CEP07180.1 - 1.1 8.4 9.2 1.8 7.7 6.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PSCyt3 PF07627.6 CEP07180.1 - 1.6 8.5 6.6 2.4 8.0 0.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1588) Macoilin PF09726.4 CEP07180.1 - 2.8 6.1 12.5 3.3 5.8 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF399 PF04187.8 CEP07182.1 - 0.091 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF399 EF-1_beta_acid PF10587.4 CEP07183.1 - 8.7 6.5 7.1 0.96 9.6 1.8 1.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region BAR_2 PF10455.4 CEP07185.1 - 4e-53 180.2 5.1 1.3e-52 178.5 3.5 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CEP07185.1 - 4.2e-20 72.2 4.4 1.6e-19 70.3 3.0 1.8 1 1 0 1 1 1 1 BAR domain Spectrin PF00435.16 CEP07185.1 - 0.004 17.4 2.8 1 9.6 0.0 2.6 2 1 0 2 2 2 2 Spectrin repeat FANCI_HD2 PF14680.1 CEP07185.1 - 0.027 13.5 0.0 0.28 10.2 0.0 2.4 1 1 2 3 3 3 0 FANCI helical domain 2 DltD_C PF04914.7 CEP07185.1 - 0.028 14.2 0.1 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 DltD C-terminal region SH3BP5 PF05276.9 CEP07185.1 - 0.095 11.9 6.8 0.66 9.2 0.1 2.2 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) TACC PF05010.9 CEP07185.1 - 0.19 11.4 5.5 1.6 8.4 0.9 2.4 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Mnd1 PF03962.10 CEP07185.1 - 0.64 9.6 4.1 5 6.7 0.1 2.3 2 0 0 2 2 2 0 Mnd1 family DUF2935 PF11155.3 CEP07185.1 - 1 9.4 4.1 6 6.9 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) IncA PF04156.9 CEP07185.1 - 1.3 8.5 5.3 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 IncA protein DivIVA PF05103.8 CEP07185.1 - 5.2 7.1 11.5 0.27 11.2 0.2 3.4 2 2 2 4 4 4 0 DivIVA protein KH_1 PF00013.24 CEP07187.1 - 0.00083 18.9 0.0 0.0021 17.6 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CEP07187.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 CEP07187.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 KH domain AAR2 PF05282.6 CEP07188.1 - 6.4e-80 268.7 0.0 1.1e-79 267.9 0.0 1.3 1 0 0 1 1 1 1 AAR2 protein Alk_phosphatase PF00245.15 CEP07189.1 - 3.9e-102 342.0 0.0 4.8e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 CEP07189.1 - 0.0036 16.7 1.7 0.0078 15.6 0.4 2.0 3 0 0 3 3 3 1 Metalloenzyme superfamily DUF3541 PF12060.3 CEP07189.1 - 0.0043 16.3 0.3 1.2 8.3 0.2 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3541) WD40 PF00400.27 CEP07191.1 - 3.8e-11 42.4 20.7 0.0002 21.1 0.8 5.7 6 1 0 6 6 6 4 WD domain, G-beta repeat F-box-like PF12937.2 CEP07191.1 - 9.5e-08 31.6 0.3 2.1e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP07191.1 - 8.1e-07 28.5 0.1 1.9e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 CEP07191.1 - 0.00089 17.5 0.0 0.0019 16.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 UIM PF02809.15 CEP07191.1 - 0.84 9.3 19.0 0.32 10.6 2.4 4.3 4 0 0 4 4 4 0 Ubiquitin interaction motif Pkinase PF00069.20 CEP07192.1 - 2e-18 66.4 0.1 2.7e-12 46.4 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07192.1 - 7.5e-10 38.3 0.2 1.9e-06 27.1 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CEP07192.1 - 0.0025 16.9 0.0 0.0051 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP07192.1 - 0.0095 15.6 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP07192.1 - 0.033 13.1 0.1 0.4 9.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Mucin PF01456.12 CEP07192.1 - 0.65 9.7 9.8 1.5 8.5 6.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein UCH PF00443.24 CEP07193.1 - 1.6e-36 125.8 4.2 1.6e-36 125.8 2.9 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP07193.1 - 5.7e-21 75.2 4.1 5.7e-21 75.2 2.9 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mod_r PF07200.8 CEP07194.1 - 0.67 9.8 16.7 0.053 13.4 3.4 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4570 PF15134.1 CEP07194.1 - 3.5 7.4 12.5 0.12 12.2 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) NST1 PF13945.1 CEP07195.1 - 4.8e-58 196.3 10.8 4.8e-58 196.3 7.5 3.6 2 1 1 3 3 3 1 Salt tolerance down-regulator bZIP_1 PF00170.16 CEP07196.1 - 1.6e-06 27.9 8.7 1.6e-06 27.9 6.1 2.0 1 1 1 2 2 2 1 bZIP transcription factor Herpes_UL6 PF01763.11 CEP07196.1 - 0.00025 19.3 2.0 0.00027 19.2 1.4 1.0 1 0 0 1 1 1 1 Herpesvirus UL6 like Glutaredoxin2_C PF04399.8 CEP07196.1 - 0.012 15.1 3.9 0.015 14.9 1.5 1.9 1 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain CCDC155 PF14662.1 CEP07196.1 - 0.015 14.9 6.0 0.021 14.4 4.1 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF3086 PF11285.3 CEP07196.1 - 0.02 13.6 0.5 0.023 13.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) ApoLp-III PF07464.6 CEP07196.1 - 0.034 14.1 2.1 0.048 13.6 1.5 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TMF_DNA_bd PF12329.3 CEP07196.1 - 0.045 13.5 2.6 0.088 12.6 1.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 CEP07196.1 - 0.11 12.2 17.7 0.12 12.2 7.5 2.9 1 1 1 2 2 2 0 Basic region leucine zipper RIO1 PF01163.17 CEP07196.1 - 0.11 11.7 1.5 0.15 11.4 1.0 1.1 1 0 0 1 1 1 0 RIO1 family bZIP_Maf PF03131.12 CEP07196.1 - 0.17 12.1 9.2 0.072 13.3 4.4 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor ADIP PF11559.3 CEP07196.1 - 0.22 11.4 11.7 0.32 10.8 8.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Nup54 PF13874.1 CEP07196.1 - 0.51 9.9 7.0 0.51 9.9 4.1 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 CEP07196.1 - 0.9 9.9 4.6 1.2 9.5 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Thyroglobulin_1 PF00086.13 CEP07197.1 - 0.035 13.4 1.3 0.052 12.9 0.9 1.3 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat SPOUT_MTase_2 PF14419.1 CEP07197.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP rve PF00665.21 CEP07198.1 - 1.2e-16 60.8 0.0 3.2e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP07198.1 - 1.7e-08 33.9 0.7 4.1e-08 32.7 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CEP07198.1 - 2.1e-08 33.7 0.1 7e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CEP07198.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.15 CEP07198.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Fungal_trans PF04082.13 CEP07199.1 - 1.2e-19 70.1 0.9 2.8e-19 69.0 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 CEP07200.1 - 1.7e-84 283.5 31.1 1.6e-46 158.9 7.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP07200.1 - 7.3e-55 185.0 0.3 5e-32 111.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.1 CEP07200.1 - 2.9e-08 33.9 2.6 0.017 15.2 0.7 3.3 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CEP07200.1 - 5.5e-08 32.3 4.8 0.001 18.3 0.9 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEP07200.1 - 2.4e-07 31.0 0.0 0.086 12.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEP07200.1 - 3.8e-07 29.4 0.1 0.014 14.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CEP07200.1 - 4.8e-07 29.9 1.3 0.037 14.0 0.3 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CEP07200.1 - 7.1e-07 28.6 1.1 0.023 14.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CEP07200.1 - 4.4e-06 27.5 0.1 0.069 13.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CEP07200.1 - 1.2e-05 24.4 0.0 0.017 14.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ABC_ATPase PF09818.4 CEP07200.1 - 4.6e-05 22.1 0.2 0.00022 19.9 0.1 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class G-alpha PF00503.15 CEP07200.1 - 0.00016 20.5 1.4 0.17 10.5 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA_30 PF13604.1 CEP07200.1 - 0.00019 21.0 1.6 1.4 8.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CEP07200.1 - 0.00071 19.8 0.3 1.2 9.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 CEP07200.1 - 0.00098 19.0 0.5 2.6 7.7 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_33 PF13671.1 CEP07200.1 - 0.0015 18.4 0.0 0.8 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEP07200.1 - 0.0024 17.3 0.2 6.1 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 CEP07200.1 - 0.0033 17.1 0.3 1.3 8.6 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CEP07200.1 - 0.0038 17.2 0.2 3 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEP07200.1 - 0.0045 16.4 0.2 4.6 6.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 CEP07200.1 - 0.0048 16.5 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase Miro PF08477.8 CEP07200.1 - 0.0064 16.9 0.9 14 6.2 0.0 3.5 3 0 0 3 3 3 0 Miro-like protein AAA_5 PF07728.9 CEP07200.1 - 0.0088 15.7 0.1 4.3 7.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CEP07200.1 - 0.015 15.4 0.0 8.6 6.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Septin PF00735.13 CEP07200.1 - 0.018 14.0 0.1 1.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 CEP07200.1 - 0.036 14.4 0.1 22 5.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CEP07200.1 - 0.044 13.2 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 CEP07200.1 - 0.077 12.6 0.1 16 5.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 CEP07200.1 - 0.38 10.7 4.6 9.5 6.2 0.1 3.2 3 1 0 3 3 2 0 50S ribosome-binding GTPase Helitron_like_N PF14214.1 CEP07201.1 - 9.9e-18 64.5 0.1 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_1 PF00078.22 CEP07203.1 - 1.9e-30 105.8 0.0 5e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP07203.1 - 0.0021 17.6 0.2 0.0055 16.3 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CEP07203.1 - 0.0039 17.4 0.8 0.0039 17.4 0.5 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Methyltransf_PK PF05891.7 CEP07204.1 - 1.4e-77 259.9 0.1 1.7e-77 259.6 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.1 CEP07204.1 - 7.5e-08 32.6 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP07204.1 - 1.3e-07 31.9 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP07204.1 - 8.5e-07 29.5 0.0 1.2e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP07204.1 - 1.6e-06 28.4 0.0 2.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP07204.1 - 2.5e-06 27.2 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP07204.1 - 0.00013 21.4 0.0 0.004 16.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.13 CEP07204.1 - 0.037 13.2 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase TMEM237 PF15383.1 CEP07204.1 - 0.041 12.9 0.0 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 237 ABC_tran PF00005.22 CEP07205.1 - 2.8e-28 98.9 0.0 4.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CEP07205.1 - 1.8e-09 37.9 0.0 1.1e-05 25.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CEP07205.1 - 7.7e-06 25.3 0.0 0.00012 21.3 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CEP07205.1 - 5e-05 23.3 0.0 0.00013 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CEP07205.1 - 0.00033 19.8 0.0 0.00055 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 CEP07205.1 - 0.00047 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 CEP07205.1 - 0.00088 18.9 0.1 0.003 17.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.1 CEP07205.1 - 0.001 18.9 0.1 0.024 14.5 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.16 CEP07205.1 - 0.0015 17.7 0.0 0.043 12.9 0.0 2.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CEP07205.1 - 0.0019 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CEP07205.1 - 0.0034 17.5 0.0 0.005 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CEP07205.1 - 0.0054 16.9 0.1 0.033 14.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CEP07205.1 - 0.0082 15.8 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_23 PF13476.1 CEP07205.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CEP07205.1 - 0.015 16.0 0.0 0.023 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CEP07205.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 CEP07205.1 - 0.016 14.9 0.0 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CEP07205.1 - 0.024 14.0 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CEP07205.1 - 0.038 13.5 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEP07205.1 - 0.04 13.7 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEP07205.1 - 0.049 13.5 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 CEP07205.1 - 0.053 12.3 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase AAA_18 PF13238.1 CEP07205.1 - 0.058 13.7 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CEP07205.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 CEP07205.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.12 CEP07205.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_15 PF13175.1 CEP07205.1 - 0.15 11.1 0.0 1.6 7.6 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 CEP07206.1 - 2.1e-59 200.8 0.1 3.2e-59 200.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07206.1 - 1.3e-19 70.2 0.0 2.3e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CEP07206.1 - 0.12 11.7 0.3 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family TPR_MLP1_2 PF07926.7 CEP07207.1 - 0.0088 15.7 14.5 0.0088 15.7 10.1 5.5 2 1 2 5 5 5 1 TPR/MLP1/MLP2-like protein Ubiq_cyt_C_chap PF03981.7 CEP07207.1 - 0.022 14.6 1.0 0.022 14.6 0.7 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C chaperone DUF3596 PF12167.3 CEP07207.1 - 0.23 10.9 1.3 0.42 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) ApoO PF09769.4 CEP07207.1 - 1.4 8.5 9.4 5.3 6.7 2.2 3.1 2 1 0 3 3 3 0 Apolipoprotein O Rtf2 PF04641.7 CEP07208.1 - 4.2e-75 252.3 10.1 5.1e-75 252.0 7.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 CEP07208.1 - 0.0016 17.9 0.1 0.042 13.3 0.0 2.7 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit YhfH PF14149.1 CEP07208.1 - 0.012 15.4 1.1 0.021 14.5 0.3 1.8 1 1 0 1 1 1 0 YhfH-like protein zf-RING_UBOX PF13445.1 CEP07208.1 - 0.013 15.1 2.4 0.018 14.7 0.8 2.0 2 0 0 2 2 2 0 RING-type zinc-finger DUF2256 PF10013.4 CEP07208.1 - 0.055 13.2 0.7 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) RNase_PH_C PF03725.10 CEP07208.1 - 0.056 13.3 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 PRTP PF01366.13 CEP07208.1 - 0.059 11.3 4.4 0.092 10.7 3.1 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Cellulose_synt PF03552.9 CEP07208.1 - 0.081 11.2 4.0 0.1 10.8 2.8 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF908 PF06012.7 CEP07208.1 - 0.097 11.9 1.2 0.099 11.9 0.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) zf-RING_2 PF13639.1 CEP07208.1 - 0.15 11.9 1.5 6.4 6.7 1.9 2.2 1 1 1 2 2 2 0 Ring finger domain ICA69 PF04629.9 CEP07208.1 - 0.5 10.2 7.1 0.87 9.5 4.9 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain DUF3987 PF13148.1 CEP07208.1 - 2.7 6.4 7.2 3.8 5.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NARP1 PF12569.3 CEP07208.1 - 8.1 5.0 14.0 12 4.5 9.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Molybdopterin PF00384.17 CEP07209.1 - 3.8e-70 236.7 0.0 2.3e-69 234.2 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 CEP07209.1 - 3e-18 65.3 0.1 1.3e-17 63.3 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 CEP07209.1 - 6.8e-18 63.6 0.1 1.7e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 CEP07209.1 - 1.9e-13 50.3 0.2 4.6e-13 49.1 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 CEP07209.1 - 6.3e-08 32.2 0.3 6.3e-08 32.2 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain zf-H2C2_2 PF13465.1 CEP07210.1 - 1.5e-09 37.6 8.6 2.3e-07 30.7 0.1 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEP07210.1 - 4.3e-09 36.1 8.5 1.2e-05 25.3 1.2 3.5 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP07210.1 - 5.4e-06 26.3 7.1 0.00014 21.9 1.4 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CEP07210.1 - 0.067 13.3 0.4 0.067 13.3 0.3 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.7 CEP07210.1 - 0.38 10.8 3.2 0.73 9.8 1.0 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.3 CEP07210.1 - 0.9 9.7 11.8 0.96 9.6 0.1 3.8 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.6 CEP07210.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-BED PF02892.10 CEP07210.1 - 5.5 6.8 6.3 4.7 7.0 1.5 2.3 1 1 1 2 2 2 0 BED zinc finger Rad21_Rec8 PF04824.11 CEP07211.1 - 8.3e-06 24.9 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CEP07211.1 - 0.00041 20.0 2.2 0.00052 19.6 0.1 2.0 2 0 0 2 2 2 1 ScpA/B protein JAB PF01398.16 CEP07212.1 - 2.3e-16 59.5 0.1 7.1e-16 57.9 0.1 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CEP07212.1 - 0.00073 19.0 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain IP_trans PF02121.13 CEP07213.1 - 1.5e-78 263.4 6.3 3.7e-78 262.2 4.3 1.5 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein DUF4174 PF13778.1 CEP07213.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) zf-HIT PF04438.11 CEP07214.1 - 2.1e-09 36.8 7.8 3.3e-09 36.2 5.4 1.3 1 0 0 1 1 1 1 HIT zinc finger NeuB PF03102.9 CEP07214.1 - 0.031 13.4 0.3 0.054 12.6 0.2 1.3 1 0 0 1 1 1 0 NeuB family PPR_2 PF13041.1 CEP07215.1 - 4.4e-68 225.0 17.7 4.2e-12 45.8 0.0 16.6 11 4 7 18 18 17 14 PPR repeat family PPR PF01535.15 CEP07215.1 - 2.5e-48 158.7 20.5 1.5e-05 24.6 0.1 18.5 21 0 0 21 21 20 10 PPR repeat PPR_3 PF13812.1 CEP07215.1 - 5.9e-37 122.8 19.2 0.00085 19.4 0.0 16.8 18 0 0 18 18 18 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEP07215.1 - 4.9e-34 115.4 0.7 2.3e-06 26.9 0.0 13.3 14 0 0 14 14 14 8 PPR repeat RPM2 PF08579.6 CEP07215.1 - 2.1e-08 34.3 4.8 3.3e-05 23.9 0.1 5.1 6 0 0 6 6 6 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_12 PF13424.1 CEP07215.1 - 4.9e-07 29.6 10.8 1.7 8.6 0.1 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP07215.1 - 3.2e-06 27.3 18.8 0.84 10.0 0.0 8.5 8 1 3 11 11 10 4 Tetratricopeptide repeat ECSIT PF06239.6 CEP07215.1 - 7.8e-05 21.6 1.9 4.1 6.2 0.0 5.3 6 0 0 6 6 6 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.1 CEP07215.1 - 0.00069 20.0 12.4 65 4.5 0.0 11.5 14 3 4 18 18 13 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP07215.1 - 0.019 14.7 9.5 6.4 6.8 0.1 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat ATP13 PF12921.2 CEP07215.1 - 0.023 14.0 0.3 20 4.5 0.0 3.8 3 0 0 3 3 3 0 Mitochondrial ATPase expression TPR_7 PF13176.1 CEP07215.1 - 0.042 13.6 6.4 12 5.9 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DRIM PF07539.7 CEP07215.1 - 0.078 12.3 2.1 0.17 11.3 0.5 2.3 2 0 0 2 2 2 0 Down-regulated in metastasis Atx10homo_assoc PF09759.4 CEP07215.1 - 0.32 10.7 4.1 1.4 8.6 0.2 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Ax_dynein_light PF10211.4 CEP07217.1 - 0.00078 19.3 0.7 0.0014 18.4 0.5 1.4 1 0 0 1 1 1 1 Axonemal dynein light chain HR1 PF02185.11 CEP07217.1 - 0.0028 17.3 1.9 0.0052 16.4 1.3 1.4 1 0 0 1 1 1 1 Hr1 repeat Lzipper-MIP1 PF14389.1 CEP07217.1 - 0.0049 16.9 0.8 0.0088 16.1 0.6 1.3 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.1 CEP07217.1 - 0.012 14.8 0.7 0.012 14.8 0.5 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CEP07217.1 - 0.013 15.3 4.2 0.028 14.2 2.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.16 CEP07217.1 - 0.015 15.5 0.6 0.036 14.3 0.4 1.6 1 0 0 1 1 1 0 Spectrin repeat Spc24 PF08286.6 CEP07217.1 - 0.016 14.8 0.7 0.031 13.9 0.5 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 CEP07217.1 - 0.018 15.4 0.2 0.03 14.7 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Tektin PF03148.9 CEP07217.1 - 0.02 13.4 0.6 0.032 12.7 0.4 1.2 1 0 0 1 1 1 0 Tektin family APG6 PF04111.7 CEP07217.1 - 0.028 13.4 0.3 0.038 13.0 0.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4201 PF13870.1 CEP07217.1 - 0.035 13.5 0.3 0.035 13.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DivIC PF04977.10 CEP07217.1 - 0.037 13.5 1.3 0.079 12.4 0.9 1.5 1 0 0 1 1 1 0 Septum formation initiator Prefoldin PF02996.12 CEP07217.1 - 0.04 13.5 1.6 0.33 10.6 1.3 2.3 3 0 0 3 3 3 0 Prefoldin subunit DUF1192 PF06698.6 CEP07217.1 - 0.041 13.6 1.2 0.086 12.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Prefoldin_2 PF01920.15 CEP07217.1 - 0.042 13.6 0.9 0.042 13.6 0.6 1.6 2 0 0 2 2 1 0 Prefoldin subunit FlaC_arch PF05377.6 CEP07217.1 - 0.051 13.4 1.4 0.051 13.4 1.0 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1878 PF08963.5 CEP07217.1 - 0.052 13.7 0.8 0.1 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Osmo_CC PF08946.5 CEP07217.1 - 0.062 13.3 7.7 2.4 8.2 1.8 2.5 2 1 0 2 2 2 0 Osmosensory transporter coiled coil Seryl_tRNA_N PF02403.17 CEP07217.1 - 0.069 13.1 2.3 0.15 12.0 1.6 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NuA4 PF09340.5 CEP07217.1 - 0.077 12.6 0.2 0.077 12.6 0.1 1.7 2 0 0 2 2 1 0 Histone acetyltransferase subunit NuA4 bZIP_1 PF00170.16 CEP07217.1 - 0.12 12.3 2.2 0.24 11.3 1.6 1.5 1 0 0 1 1 1 0 bZIP transcription factor DASH_Dam1 PF08653.5 CEP07217.1 - 0.12 12.1 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 IncA PF04156.9 CEP07217.1 - 0.13 11.8 0.2 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 CEP07217.1 - 0.13 12.0 1.4 0.23 11.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Bap31 PF05529.7 CEP07217.1 - 0.17 11.3 2.4 0.26 10.7 1.7 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1033 PF06279.6 CEP07217.1 - 0.62 9.8 3.9 1.9 8.2 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1033) Cep57_CLD_2 PF14197.1 CEP07219.1 - 0.073 13.0 6.7 0.23 11.4 4.7 1.9 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Methyltransf_29 PF03141.11 CEP07219.1 - 0.13 10.6 3.8 0.2 9.9 0.2 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ARGLU PF15346.1 CEP07219.1 - 0.41 10.4 19.7 0.31 10.8 9.6 2.4 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF4112 PF13430.1 CEP07220.1 - 7.6e-34 115.8 2.2 9.7e-34 115.4 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Syja_N PF02383.13 CEP07222.1 - 2.1e-64 217.3 0.0 8.9e-64 215.2 0.0 1.9 1 1 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CEP07222.1 - 4.9e-27 95.4 0.2 8.5e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDE_3 PF13358.1 CEP07223.1 - 8.9e-06 25.5 0.1 0.00081 19.1 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease IFRD_C PF04836.7 CEP07223.1 - 0.082 13.0 1.0 0.2 11.8 0.7 1.6 1 0 0 1 1 1 0 Interferon-related protein conserved region Terminase_6 PF03237.10 CEP07223.1 - 0.083 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family EI24 PF07264.6 CEP07224.1 - 2.7e-20 72.7 9.8 6e-18 65.0 3.5 2.2 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DctQ PF04290.7 CEP07224.1 - 0.4 10.4 5.8 0.13 11.9 1.5 2.0 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component PUF PF00806.14 CEP07225.1 - 3.3e-22 76.6 0.1 0.0018 17.6 0.0 7.5 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 CEP07225.1 - 0.00017 21.4 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP07225.1 - 0.00033 20.2 0.1 0.00099 18.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidohydro_1 PF01979.15 CEP07227.1 - 1.5e-25 90.5 0.0 1.8e-24 87.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CEP07227.1 - 5.1e-25 89.0 0.1 6e-24 85.5 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 CEP07227.1 - 1.6e-09 37.3 0.1 5.1e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CEP07227.1 - 2.4e-09 36.9 0.6 0.00012 21.3 0.0 3.1 2 1 1 3 3 3 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 CEP07227.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 G6PD_C PF02781.11 CEP07228.1 - 1.7e-123 411.1 0.1 2.2e-123 410.8 0.1 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CEP07228.1 - 8.2e-60 202.1 0.0 1.9e-59 200.9 0.0 1.6 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DMAP1 PF05499.7 CEP07229.1 - 0.0014 18.2 9.8 0.0037 16.8 5.1 2.7 2 1 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.1 CEP07229.1 - 0.0088 16.1 2.6 0.025 14.6 0.1 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP07229.1 - 0.58 10.2 2.9 0.78 9.8 0.0 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain SlyX PF04102.7 CEP07229.1 - 8.8 6.7 12.2 22 5.4 2.6 3.1 1 1 1 2 2 2 0 SlyX Sec39 PF08314.6 CEP07230.1 - 2.6e-68 230.6 0.2 4.4e-68 229.9 0.1 1.3 1 0 0 1 1 1 1 Secretory pathway protein Sec39 INTS2 PF14750.1 CEP07231.1 - 2.5e-06 25.3 6.7 4.8e-06 24.4 4.7 1.3 1 1 0 1 1 1 1 Integrator complex subunit 2 MIP-T3 PF10243.4 CEP07232.1 - 6.6 5.0 52.1 8.5 4.7 36.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPF0102 PF02021.12 CEP07233.1 - 0.00013 21.8 8.9 2.9 7.8 0.1 4.8 4 1 0 5 5 5 3 Uncharacterised protein family UPF0102 DUF4391 PF14335.1 CEP07233.1 - 0.011 15.0 0.7 4.7 6.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4391) DNA_pol_B_palm PF14792.1 CEP07233.1 - 0.26 11.3 13.6 17 5.5 0.0 5.2 2 1 5 7 7 7 0 DNA polymerase beta palm DUF4141 PF13605.1 CEP07233.1 - 0.96 8.6 12.1 9 5.5 0.1 5.5 7 0 0 7 7 7 0 Domain of unknown function (DUF4141) zf-CpG_bind_C PF12269.3 CEP07235.1 - 0.11 11.9 1.4 0.16 11.3 1.0 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain BAR_2 PF10455.4 CEP07237.1 - 0.024 13.5 0.2 0.036 12.9 0.1 1.5 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Bud13 PF09736.4 CEP07238.1 - 0.0075 16.5 14.5 0.0075 16.5 10.1 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Pyr_redox_3 PF13738.1 CEP07238.1 - 0.26 11.3 7.2 0.53 10.3 4.8 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LMBR1 PF04791.11 CEP07238.1 - 0.75 8.3 3.2 1 7.8 2.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF342 PF03961.8 CEP07238.1 - 6.1 5.1 8.4 9.4 4.5 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 CEP07238.1 - 6.7 6.6 33.4 1.9 8.4 19.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Peptidase_S15 PF02129.13 CEP07238.1 - 8.4 5.7 14.9 0.29 10.5 5.7 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Amidinotransf PF02274.12 CEP07239.1 - 3.6e-34 118.1 0.1 4.4e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 Amidinotransferase TLD PF07534.11 CEP07240.1 - 5e-39 133.4 0.4 9.8e-39 132.5 0.3 1.5 1 0 0 1 1 1 1 TLD RAB3GAP2_N PF14655.1 CEP07240.1 - 0.97 8.3 6.3 2 7.3 4.3 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF-4B PF06273.6 CEP07240.1 - 1.7 7.3 6.4 2.6 6.6 4.5 1.4 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Rav1p_C PF12234.3 CEP07241.1 - 2.7e-143 478.4 3.5 1.8e-142 475.6 2.4 2.1 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 CEP07241.1 - 4.4e-16 58.0 15.8 9e-08 31.7 0.1 8.4 9 0 0 9 9 9 4 WD domain, G-beta repeat PP2C_2 PF13672.1 CEP07242.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C HAD_2 PF13419.1 CEP07244.1 - 4.4e-18 66.1 0.0 1e-17 64.9 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP07244.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CEP07244.1 - 0.0036 17.7 0.0 0.017 15.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sds3 PF08598.6 CEP07245.1 - 6.5e-11 42.1 22.8 3.2e-07 30.0 5.2 2.8 2 2 1 3 3 3 2 Sds3-like LRR_4 PF12799.2 CEP07246.1 - 1.5e-36 123.3 84.1 3.1e-09 36.2 4.1 7.2 2 1 8 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP07246.1 - 2.1e-15 56.2 62.3 1.1e-06 28.3 4.4 5.1 2 1 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.1 CEP07246.1 - 1.1e-13 51.1 19.6 1.7e-06 27.7 5.6 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 CEP07246.1 - 4.9e-08 31.9 44.5 0.66 10.2 0.3 11.1 12 0 0 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.1 CEP07246.1 - 2.3e-07 30.1 34.3 0.79 9.9 0.0 10.4 4 3 5 9 9 9 5 Leucine Rich repeat LRR_7 PF13504.1 CEP07246.1 - 5.6e-07 28.7 24.7 3.2 8.3 0.0 9.5 8 2 0 8 8 8 3 Leucine rich repeat DUF3744 PF12558.3 CEP07246.1 - 0.047 14.1 17.2 0.49 10.8 0.7 4.9 1 1 3 4 4 4 0 ATP-binding cassette cobalt transporter ubiquitin PF00240.18 CEP07247.1 - 6.1e-25 86.4 2.1 1.5e-21 75.5 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CEP07247.1 - 1.6e-13 50.0 0.5 1e-12 47.5 0.3 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEP07247.1 - 0.0078 16.4 0.1 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CEP07247.1 - 0.016 14.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Telomere stability and silencing Med19 PF10278.4 CEP07248.1 - 0.0067 16.1 0.3 0.0071 16.0 0.2 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 FliX PF10768.4 CEP07248.1 - 0.028 14.6 0.0 0.028 14.6 0.0 1.0 1 0 0 1 1 1 0 Class II flagellar assembly regulator ubiquitin PF00240.18 CEP07251.1 - 1.5e-67 222.9 9.4 5.7e-34 115.3 1.0 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CEP07251.1 - 2.1e-39 133.0 9.3 1.1e-19 69.8 1.0 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEP07251.1 - 1.7e-11 44.2 3.5 0.00014 21.9 0.2 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CEP07251.1 - 4.2e-10 39.5 0.1 0.00056 19.6 0.0 2.1 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CEP07251.1 - 1.4e-06 28.1 0.4 0.066 13.0 0.1 2.7 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEP07251.1 - 2.6e-06 27.5 0.2 0.048 13.8 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CEP07251.1 - 0.00032 20.6 0.0 0.62 10.1 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2870) CDC48_2 PF02933.12 CEP07251.1 - 0.01 15.4 4.2 1.5 8.5 0.4 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 TUG-UBL1 PF11470.3 CEP07251.1 - 0.013 15.4 1.0 2.5 8.0 0.1 2.3 2 0 0 2 2 2 0 GLUT4 regulating protein TUG FlgD_ig PF13860.1 CEP07251.1 - 0.016 14.9 0.4 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain Big_3_3 PF13750.1 CEP07251.1 - 0.02 14.3 0.0 5.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) GABP-alpha PF11620.3 CEP07251.1 - 0.034 14.1 2.1 2.1 8.4 0.1 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF3861 PF12977.2 CEP07251.1 - 0.037 14.1 1.0 7.1 6.8 0.0 2.4 2 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) Plexin_cytopl PF08337.7 CEP07251.1 - 0.042 12.1 5.5 2.3 6.4 0.1 3.4 2 1 1 3 3 3 0 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 CEP07251.1 - 0.064 13.1 4.4 1.9 8.4 0.3 2.3 1 1 1 2 2 2 0 DnaJ C terminal domain ACT_4 PF13291.1 CEP07251.1 - 0.091 13.1 0.2 17 5.8 0.0 2.3 2 0 0 2 2 2 0 ACT domain Peptidase_S80 PF07230.6 CEP07251.1 - 0.37 9.0 2.6 5.7 5.1 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage T4-like capsid assembly protein (Gp20) Tash_PEST PF07708.6 CEP07251.1 - 2.1 8.4 9.0 9.3 6.3 0.9 2.3 2 0 0 2 2 2 0 Tash protein PEST motif MFS_1 PF07690.11 CEP07252.1 - 4e-21 75.1 35.7 5.9e-21 74.5 24.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP07252.1 - 1.3e-05 24.0 25.2 9.8e-05 21.1 6.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Phage_holin_5 PF06946.6 CEP07252.1 - 0.56 10.4 3.7 6.7 6.9 0.3 2.8 2 0 0 2 2 2 0 Phage holin DUF1228 PF06779.9 CEP07252.1 - 8.7 6.4 9.5 0.44 10.6 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) Kinesin PF00225.18 CEP07253.1 - 7.1e-98 327.3 0.3 7.1e-98 327.3 0.2 4.4 2 2 1 3 3 3 1 Kinesin motor domain Ribosomal_L4 PF00573.17 CEP07253.1 - 3.3e-39 134.2 0.8 3.3e-39 134.2 0.6 2.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CEP07253.1 - 9.6e-28 95.8 7.1 1.8e-27 95.0 2.9 3.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Homeobox_KN PF05920.6 CEP07254.1 - 2.4e-17 62.3 0.7 5.8e-17 61.1 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CEP07254.1 - 2.4e-08 33.4 0.6 9e-08 31.6 0.4 2.0 1 0 0 1 1 1 1 Homeobox domain DUF643 PF04867.7 CEP07254.1 - 0.12 12.8 0.0 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF643) DUF3439 PF11921.3 CEP07254.1 - 0.66 9.7 7.8 0.34 10.6 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RhoGAP PF00620.22 CEP07255.1 - 6.1e-08 32.4 0.3 4e-07 29.7 0.1 2.4 2 1 0 2 2 2 1 RhoGAP domain PAT1 PF09770.4 CEP07255.1 - 0.18 9.9 33.7 0.25 9.5 23.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Trypan_PARP PF05887.6 CEP07255.1 - 0.4 10.4 8.7 0.019 14.8 2.2 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.8 CEP07255.1 - 4.8 6.9 25.0 6.7 6.4 17.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit vMSA PF00695.14 CEP07255.1 - 4.9 6.2 9.7 7.2 5.7 6.7 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Suf PF05843.9 CEP07256.1 - 5e-68 229.8 16.4 5e-68 229.8 11.4 6.2 4 3 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CEP07256.1 - 2.5e-06 27.5 0.1 4.7 8.1 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEP07256.1 - 2.7e-05 24.4 0.6 0.048 13.9 0.3 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP07256.1 - 0.00097 19.7 0.2 2.3 8.9 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEP07256.1 - 0.0011 18.5 1.4 0.0043 16.6 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 CEP07256.1 - 0.069 13.3 0.6 38 4.8 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP07256.1 - 0.12 12.8 1.6 36 5.1 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat rve PF00665.21 CEP07257.1 - 8.8e-17 61.3 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP07257.1 - 1.8e-11 43.5 1.5 1.6e-10 40.5 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP07257.1 - 0.047 13.3 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DDE_3 PF13358.1 CEP07258.1 - 9.4e-32 109.7 0.0 1.8e-31 108.8 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP07258.1 - 0.0004 19.5 0.1 0.0016 17.6 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease GATase_4 PF13230.1 CEP07258.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II MULE PF10551.4 CEP07258.1 - 0.027 14.6 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain rve PF00665.21 CEP07258.1 - 0.096 12.7 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain Ricin_B_lectin PF00652.17 CEP07259.1 - 7.9e-52 174.5 26.5 5.2e-10 39.4 0.6 15.7 9 5 4 14 14 14 13 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP07259.1 - 7.8e-24 84.0 31.2 5.1e-05 23.5 0.1 12.8 10 3 4 14 14 14 8 Ricin-type beta-trefoil lectin domain-like TB2_DP1_HVA22 PF03134.14 CEP07260.1 - 9.1e-17 60.5 1.6 2e-16 59.4 1.1 1.6 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Cyclin_N PF00134.18 CEP07260.1 - 3.9e-10 39.3 1.2 9.1e-10 38.1 0.8 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CEP07260.1 - 9.8e-05 22.8 1.8 0.00018 21.9 0.0 2.4 3 0 0 3 3 3 1 Cyclin Cpn60_TCP1 PF00118.19 CEP07261.1 - 8.9e-16 57.5 0.0 9.5e-16 57.4 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family M20_dimer PF07687.9 CEP07262.1 - 3.3e-10 39.7 0.0 1e-08 34.8 0.0 3.0 3 0 0 3 3 3 1 Peptidase dimerisation domain Eapp_C PF10238.4 CEP07262.1 - 0.72 9.7 7.8 2.1 8.2 5.4 2.0 1 1 0 1 1 1 0 E2F-associated phosphoprotein GTP_cyclohydroI PF01227.17 CEP07263.1 - 1.7e-76 255.5 0.4 2e-76 255.2 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CEP07263.1 - 5.4e-06 26.2 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein F-box-like PF12937.2 CEP07264.1 - 1.8e-05 24.3 0.1 5.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like Complex1_LYR PF05347.10 CEP07265.1 - 4.6e-07 29.5 0.4 8.4e-07 28.6 0.2 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEP07265.1 - 1.9e-05 24.8 0.2 3.9e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CEP07265.1 - 0.0095 16.4 0.4 0.012 16.1 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RhoGEF PF00621.15 CEP07266.1 - 2e-36 125.5 1.8 4.5e-36 124.4 1.2 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 CEP07266.1 - 8.5e-07 29.1 0.6 3.2e-06 27.2 0.1 2.3 2 0 0 2 2 2 1 PH domain Tox-MPTase5 PF15641.1 CEP07266.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 5 Caleosin PF05042.8 CEP07267.1 - 4.8e-30 104.3 0.0 6.9e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Caleosin related protein RVT_1 PF00078.22 CEP07268.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Multi_Drug_Res PF00893.14 CEP07268.1 - 0.24 11.8 1.5 7.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Small Multidrug Resistance protein WBP-1 PF11669.3 CEP07270.1 - 0.18 11.8 1.8 0.3 11.1 1.2 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 Alpha_adaptinC2 PF02883.15 CEP07271.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Adaptin C-terminal domain DNA_pol_A_exo1 PF01612.15 CEP07273.1 - 4e-12 45.9 0.0 6.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease MRP-L28 PF09812.4 CEP07274.1 - 2.4e-18 66.4 1.0 2.9e-18 66.2 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Med12-LCEWAV PF12145.3 CEP07274.1 - 0.062 11.7 0.0 0.069 11.6 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain DUF241 PF03087.9 CEP07274.1 - 0.079 12.4 0.3 0.078 12.4 0.2 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Aa_trans PF01490.13 CEP07276.1 - 4.1e-60 203.3 28.5 4.8e-60 203.1 19.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Retrotrans_gag PF03732.12 CEP07277.1 - 0.02 14.9 0.6 0.056 13.5 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein NESP55 PF06390.7 CEP07277.1 - 6.7 6.0 9.0 23 4.2 4.2 2.2 1 1 1 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) RRM_1 PF00076.17 CEP07278.1 - 8.5e-15 54.1 0.0 1.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07278.1 - 1.7e-08 34.2 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 CEP07278.1 - 1.7e-07 30.8 4.9 2.9e-07 30.1 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.1 CEP07278.1 - 6.1e-05 22.7 0.0 9.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.17 CEP07278.1 - 0.0087 15.8 0.2 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC_5 PF14787.1 CEP07278.1 - 0.022 14.2 3.5 0.041 13.3 2.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 CEP07278.1 - 0.17 11.6 1.1 0.34 10.6 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Occludin_ELL PF07303.8 CEP07279.1 - 0.58 10.9 3.8 1.2 9.9 0.2 2.6 3 0 0 3 3 3 0 Occludin homology domain FCH PF00611.18 CEP07280.1 - 3.5e-14 52.7 1.4 1.1e-12 47.9 0.0 3.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 CEP07280.1 - 1.2e-13 50.9 0.1 9.8e-13 47.9 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 CEP07280.1 - 6.4e-08 32.2 0.0 2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Gal4_dimer PF03902.8 CEP07280.1 - 0.0059 16.5 0.3 0.3 11.0 0.0 2.8 2 0 0 2 2 2 1 Gal4-like dimerisation domain BAR PF03114.13 CEP07280.1 - 0.0098 15.4 1.6 0.0098 15.4 1.1 2.6 2 0 0 2 2 2 1 BAR domain Glutaminase PF04960.10 CEP07280.1 - 0.033 13.1 0.1 0.058 12.3 0.1 1.3 1 0 0 1 1 1 0 Glutaminase CBFD_NFYB_HMF PF00808.18 CEP07281.1 - 2.8e-13 49.6 0.0 6.8e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YlbD_coat PF14071.1 CEP07281.1 - 0.0048 16.9 0.4 0.0048 16.9 0.3 2.2 2 0 0 2 2 2 1 Putative coat protein TFIIA PF03153.8 CEP07281.1 - 0.01 15.7 12.4 0.011 15.7 8.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.19 CEP07281.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TAFII55_N PF04658.8 CEP07281.1 - 0.1 12.1 5.2 0.23 10.9 3.6 1.7 1 1 0 1 1 1 0 TAFII55 protein conserved region BUD22 PF09073.5 CEP07281.1 - 0.54 9.2 21.1 0.61 9.0 14.6 1.1 1 0 0 1 1 1 0 BUD22 Spore_coat_CotO PF14153.1 CEP07281.1 - 1.2 8.5 18.6 1.8 8.0 12.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Astro_capsid PF03115.9 CEP07281.1 - 1.5 7.0 8.4 1.6 6.8 5.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RNA_pol_3_Rpc31 PF11705.3 CEP07281.1 - 1.7 8.5 20.8 2.5 7.9 14.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_S49_N PF08496.5 CEP07281.1 - 5.6 6.7 10.7 0.079 12.7 1.2 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal DUF2201_N PF13203.1 CEP07281.1 - 5.9 5.9 9.9 6.7 5.7 6.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain NOA36 PF06524.7 CEP07281.1 - 8.2 5.5 11.9 11 5.2 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein GST_N_3 PF13417.1 CEP07282.1 - 4.4e-20 71.6 0.1 8e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP07282.1 - 2e-16 59.8 0.0 5.8e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP07282.1 - 3.6e-14 52.5 0.0 7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEP07282.1 - 4.1e-05 23.4 0.0 9.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP07282.1 - 0.00071 20.0 0.0 0.0057 17.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEP07282.1 - 0.0051 16.6 0.0 0.0095 15.8 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 CEP07282.1 - 0.071 13.3 0.1 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Glutaredoxin PF00462.19 CEP07282.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin WWbp PF10349.4 CEP07283.1 - 2e-08 35.1 0.2 1.2e-07 32.6 0.1 2.3 2 1 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 CEP07283.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.5 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Rtt106 PF08512.7 CEP07283.1 - 0.027 14.4 0.0 0.35 10.8 0.0 2.1 1 1 0 1 1 1 0 Histone chaperone Rttp106-like Peptidase_M1 PF01433.15 CEP07285.1 - 6.4e-139 463.3 0.2 9.3e-139 462.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CEP07285.1 - 2e-54 185.0 0.8 2e-54 185.0 0.5 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CEP07285.1 - 2.2e-17 63.2 2.3 5.2e-17 62.0 1.6 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Aminotran_1_2 PF00155.16 CEP07285.1 - 0.0083 15.1 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II DDE_Tnp_1_7 PF13843.1 CEP07286.1 - 9.2e-07 28.2 0.2 1.7e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Transposase IS4 Pyr_redox_2 PF07992.9 CEP07287.1 - 1.9e-26 93.1 0.0 1e-17 64.6 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP07287.1 - 2e-12 47.3 0.0 1.5e-11 44.5 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP07287.1 - 0.00038 20.5 0.0 1.8 8.5 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEP07287.1 - 0.13 10.6 0.7 0.93 7.8 0.0 2.1 1 1 1 2 2 2 0 HI0933-like protein Pex19 PF04614.7 CEP07288.1 - 1.7e-60 204.7 23.3 1.7e-60 204.7 16.2 1.8 1 1 0 2 2 2 1 Pex19 protein family Host_attach PF10116.4 CEP07288.1 - 0.0056 16.9 1.1 0.71 10.0 0.1 2.9 2 1 0 2 2 2 2 Protein required for attachment to host cells GlutR_dimer PF00745.15 CEP07288.1 - 0.16 11.8 1.0 1.6 8.7 0.1 2.8 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain SGS PF05002.10 CEP07288.1 - 0.29 10.9 8.9 0.49 10.1 0.1 3.6 3 0 0 3 3 3 0 SGS domain Caldesmon PF02029.10 CEP07289.1 - 0.005 15.3 3.7 0.0056 15.1 2.6 1.0 1 0 0 1 1 1 1 Caldesmon DUF1510 PF07423.6 CEP07289.1 - 0.19 11.0 3.3 0.21 10.9 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DAP PF15228.1 CEP07289.1 - 0.28 11.9 4.3 1.1 10.0 3.0 2.0 1 1 0 1 1 1 0 Death-associated protein MADF_DNA_bdg PF10545.4 CEP07290.1 - 0.31 11.2 5.3 2.2 8.5 0.0 3.5 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ribosomal_L30 PF00327.15 CEP07291.1 - 2.3e-18 65.5 0.9 4.4e-18 64.6 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CEP07291.1 - 9.2e-16 57.6 18.3 1.7e-15 56.7 5.3 2.4 2 0 0 2 2 2 2 Ribosomal L30 N-terminal domain Ribosomal_L14e PF01929.12 CEP07293.1 - 1.1e-25 89.8 4.8 1.8e-25 89.0 3.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CEP07293.1 - 0.0061 16.2 0.4 0.012 15.2 0.3 1.5 1 0 0 1 1 1 1 KOW motif U6-snRNA_bdg PF10596.4 CEP07293.1 - 0.025 13.9 0.3 0.035 13.4 0.2 1.2 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 DUF3889 PF13028.1 CEP07293.1 - 1.7 8.3 4.3 50 3.6 3.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3889) UCH PF00443.24 CEP07294.1 - 3.8e-78 262.3 0.0 9.8e-76 254.4 0.0 3.9 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase EST1_DNA_bind PF10373.4 CEP07294.1 - 3.9e-24 85.3 1.9 3.9e-24 85.3 1.3 2.5 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain UCH_1 PF13423.1 CEP07294.1 - 2.3e-17 63.3 0.7 4.2e-12 46.1 0.0 4.1 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase EST1 PF10374.4 CEP07294.1 - 3.2e-08 33.6 2.2 3.2e-08 33.6 1.5 3.9 4 1 0 4 4 4 1 Telomerase activating protein Est1 PIN_4 PF13638.1 CEP07294.1 - 6.7e-07 29.4 7.3 8.5e-05 22.6 0.3 3.7 3 0 0 3 3 3 2 PIN domain SlyX PF04102.7 CEP07294.1 - 0.026 14.8 5.2 0.48 10.8 0.6 3.5 3 0 0 3 3 3 0 SlyX TPR_17 PF13431.1 CEP07294.1 - 0.031 14.4 0.0 0.15 12.3 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP07294.1 - 0.043 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 TPR repeat SET PF00856.23 CEP07295.1 - 3.9e-23 82.5 0.1 3.9e-23 82.5 0.1 3.3 3 2 0 3 3 3 1 SET domain WW PF00397.21 CEP07295.1 - 1.2e-07 31.4 0.6 2.8e-07 30.2 0.4 1.7 1 0 0 1 1 1 1 WW domain SRI PF08236.6 CEP07295.1 - 2.7e-05 24.0 1.8 0.00011 22.1 1.2 2.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 CEP07295.1 - 0.00092 18.6 0.0 0.0033 16.9 0.0 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Methyltrn_RNA_4 PF09936.4 CEP07295.1 - 0.041 13.3 0.1 0.095 12.1 0.0 1.6 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase 2OG-FeII_Oxy_5 PF13759.1 CEP07296.1 - 0.033 14.4 3.4 0.054 13.7 0.0 2.9 3 0 0 3 3 3 0 Putative 2OG-Fe(II) oxygenase Hexokinase_2 PF03727.11 CEP07297.1 - 1.9e-69 233.5 0.0 3.2e-69 232.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEP07297.1 - 7.4e-51 172.4 0.0 1.2e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Oxysterol_BP PF01237.13 CEP07298.1 - 1.2e-73 247.6 0.3 1.5e-73 247.3 0.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein VPS9 PF02204.13 CEP07299.1 - 1.3e-30 105.4 0.2 5.9e-30 103.3 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CEP07299.1 - 0.0018 17.7 0.0 0.0058 16.0 0.0 1.9 1 0 0 1 1 1 1 CUE domain IFT20 PF14931.1 CEP07299.1 - 0.035 13.9 0.6 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 CoA_trans PF01144.18 CEP07301.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Coenzyme A transferase ALAD PF00490.16 CEP07304.1 - 6e-124 413.1 0.0 6.6e-124 413.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PEP_mutase PF13714.1 CEP07304.1 - 0.018 14.2 0.3 2.5 7.2 0.0 2.3 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Amidohydro_2 PF04909.9 CEP07304.1 - 0.026 14.0 0.1 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Hemerythrin PF01814.18 CEP07304.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Exo_endo_phos PF03372.18 CEP07305.1 - 4.6e-14 52.9 0.7 6.9e-14 52.3 0.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LETM1 PF07766.8 CEP07305.1 - 0.12 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 LETM1-like protein tRNA-synt_1b PF00579.20 CEP07306.1 - 7.4e-71 238.6 0.0 9.9e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4434 PF14488.1 CEP07307.1 - 0.0081 15.9 1.0 0.014 15.1 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4434) ATG16 PF08614.6 CEP07307.1 - 0.13 12.0 9.3 0.8 9.4 6.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BEX PF04538.7 CEP07307.1 - 0.24 11.6 6.5 1.6 9.0 0.1 2.6 3 0 0 3 3 3 0 Brain expressed X-linked like family Pkinase PF00069.20 CEP07308.1 - 1.5e-64 217.6 0.0 5.6e-64 215.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07308.1 - 4.8e-37 127.4 0.0 1.6e-32 112.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEP07308.1 - 1e-08 34.5 0.0 2.4e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CEP07308.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CEP07308.1 - 0.051 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-N PF05238.8 CEP07309.1 - 2.9e-21 76.0 0.6 2.9e-20 72.6 0.4 2.3 1 1 0 1 1 1 1 Kinetochore protein CHL4 like oligo_HPY PF08352.7 CEP07309.1 - 0.15 12.4 0.1 0.67 10.3 0.0 2.1 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Hist_deacetyl PF00850.14 CEP07310.1 - 3.4e-84 282.8 0.0 5.3e-84 282.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Chromo PF00385.19 CEP07310.1 - 0.0085 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CIAPIN1 PF05093.8 CEP07311.1 - 3.1e-28 97.7 5.2 6.3e-28 96.8 3.6 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pantoate_transf PF02548.10 CEP07312.1 - 4.4e-106 353.7 0.1 5.2e-106 353.5 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CEP07312.1 - 7.3e-05 22.0 0.9 0.00027 20.2 0.6 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase rve PF00665.21 CEP07313.1 - 2.1e-14 53.6 0.0 3.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP07313.1 - 3.1e-11 42.7 0.6 7.4e-11 41.5 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pex14_N PF04695.8 CEP07314.1 - 0.011 15.8 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Transposase_31 PF04754.7 CEP07315.1 - 0.017 14.4 0.0 0.05 12.9 0.0 1.8 1 0 0 1 1 1 0 Putative transposase, YhgA-like DUF1162 PF06650.7 CEP07317.1 - 1.6e-68 230.9 0.1 7.3e-65 218.9 0.1 3.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CEP07317.1 - 5.8e-37 125.8 0.1 5.8e-37 125.8 0.1 2.9 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter CASP_C PF08172.7 CEP07317.1 - 3.5e-35 121.2 11.0 1.2e-27 96.5 2.0 5.4 3 2 2 5 5 5 2 CASP C terminal ATG_C PF09333.6 CEP07317.1 - 6.1e-08 32.7 1.0 5e-07 29.8 0.0 3.1 4 0 0 4 4 4 1 ATG C terminal domain Choline_transpo PF04515.7 CEP07317.1 - 1.3 7.6 0.0 2.3 6.8 0.0 1.3 1 0 0 1 1 1 0 Plasma-membrane choline transporter PPR_2 PF13041.1 CEP07318.1 - 3.4e-60 199.8 18.2 1.5e-11 44.0 0.0 8.2 3 1 5 8 8 8 8 PPR repeat family PPR_3 PF13812.1 CEP07318.1 - 2.3e-47 155.2 4.4 8.5e-08 31.9 0.0 9.1 9 0 0 9 9 9 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEP07318.1 - 1.4e-38 130.0 5.6 4.1e-08 32.5 0.0 8.5 9 0 0 9 9 9 6 PPR repeat PPR PF01535.15 CEP07318.1 - 2.6e-38 127.3 10.4 1e-07 31.4 0.1 8.6 9 0 0 9 9 9 7 PPR repeat RPM2 PF08579.6 CEP07318.1 - 0.0014 18.7 7.2 0.82 9.8 0.0 5.3 3 2 2 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 CEP07318.1 - 0.0038 16.1 0.2 0.04 12.7 0.0 2.6 2 1 1 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway DUF849 PF05853.7 CEP07318.1 - 0.0093 14.8 2.5 1.2 7.9 0.2 3.3 2 2 1 4 4 4 2 Prokaryotic protein of unknown function (DUF849) RVT_1 PF00078.22 CEP07320.1 - 0.00033 20.0 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP07321.1 - 3.3e-07 29.9 0.1 7.1e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Phage_integrase PF00589.17 CEP07322.1 - 4.8e-05 23.0 0.3 0.00012 21.7 0.2 1.6 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 CEP07322.1 - 0.012 15.0 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_4 PF13495.1 CEP07322.1 - 0.021 15.1 0.2 0.089 13.1 0.2 2.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FH2 PF02181.18 CEP07324.1 - 2.2e-85 286.7 4.8 2.2e-85 286.7 3.4 2.2 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CEP07324.1 - 4.2e-45 153.5 0.8 4.2e-45 153.5 0.5 3.5 2 1 1 3 3 3 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 CEP07324.1 - 2.3e-28 98.8 7.2 1.7e-17 63.4 0.1 3.5 3 1 1 4 4 4 2 Diaphanous GTPase-binding Domain DUF4250 PF14056.1 CEP07324.1 - 3.6 7.3 8.7 0.54 10.0 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) RVT_1 PF00078.22 CEP07325.1 - 2.8e-34 118.3 0.0 5.8e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP07325.1 - 3e-08 33.3 0.4 7.9e-08 31.9 0.3 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP07325.1 - 0.0019 18.2 1.0 0.0046 16.9 0.7 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 CEP07325.1 - 0.01 15.7 0.7 0.033 14.1 0.5 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-RVT PF13966.1 CEP07325.1 - 0.066 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase CDC45 PF02724.9 CEP07325.1 - 0.64 7.9 10.3 1 7.2 7.1 1.3 1 0 0 1 1 1 0 CDC45-like protein DDE_1 PF03184.14 CEP07326.1 - 1.5e-06 27.5 0.0 4.9e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CEP07326.1 - 3.3e-06 26.8 0.0 9.8e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Helitron_like_N PF14214.1 CEP07327.1 - 8.9e-50 168.9 0.0 1.2e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PVL_ORF50 PF07768.6 CEP07330.1 - 0.043 13.8 0.2 0.094 12.7 0.0 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family DUF739 PF05339.6 CEP07330.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF739) SAGA-Tad1 PF12767.2 CEP07333.1 - 1.8e-46 158.8 0.0 2.7e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit CRAL_TRIO PF00650.15 CEP07334.1 - 1.6e-18 66.7 0.2 2.8e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP07334.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain F-box-like PF12937.2 CEP07335.1 - 1.5e-06 27.8 1.2 5.8e-06 25.9 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP07335.1 - 0.026 14.1 0.2 0.07 12.8 0.2 1.8 1 0 0 1 1 1 0 F-box domain NOC3p PF07540.6 CEP07336.1 - 3.3e-29 101.0 0.5 3.3e-29 101.0 0.3 3.8 4 0 0 4 4 4 1 Nucleolar complex-associated protein CBF PF03914.12 CEP07336.1 - 3.6e-22 78.5 0.1 3.6e-22 78.5 0.1 3.1 2 1 0 2 2 2 1 CBF/Mak21 family Pkinase PF00069.20 CEP07337.1 - 5.5e-61 205.9 0.1 7.2e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07337.1 - 2.8e-31 108.5 0.0 4e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP07337.1 - 0.00013 21.0 0.0 0.00059 18.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 CEP07337.1 - 0.056 12.7 0.1 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CEP07337.1 - 0.11 12.1 0.3 0.27 10.9 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cons_hypoth698 PF03601.9 CEP07338.1 - 2.8e-35 121.4 14.8 3.7e-30 104.6 9.4 2.4 2 0 0 2 2 2 2 Conserved hypothetical protein 698 Glt_symporter PF03616.9 CEP07338.1 - 0.0016 16.9 12.3 0.006 15.1 3.4 2.4 2 0 0 2 2 2 2 Sodium/glutamate symporter DUF4229 PF14012.1 CEP07338.1 - 0.66 9.9 5.4 5 7.1 3.7 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Statherin PF03875.8 CEP07340.1 - 0.46 10.4 3.5 0.74 9.7 2.5 1.4 1 0 0 1 1 1 0 Statherin F-box-like PF12937.2 CEP07341.1 - 4.6e-08 32.6 0.0 9.4e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP07341.1 - 0.0007 19.1 0.0 0.0023 17.5 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 CEP07341.1 - 0.0078 15.9 10.7 0.64 9.8 1.4 5.0 2 2 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 CEP07341.1 - 0.75 9.4 14.4 3.9 7.2 0.2 6.1 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) CPSF_A PF03178.10 CEP07342.1 - 1.9e-88 296.6 0.1 9.1e-88 294.4 0.1 2.2 2 0 0 2 2 2 1 CPSF A subunit region Ribosomal_S28e PF01200.13 CEP07342.1 - 1.3e-31 108.1 1.4 3.1e-31 106.9 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S28e OrfB_Zn_ribbon PF07282.6 CEP07343.1 - 1.4e-09 37.4 0.1 1.4e-09 37.4 0.1 3.0 3 0 0 3 3 3 1 Putative transposase DNA-binding domain zf-CCHC PF00098.18 CEP07343.1 - 0.22 11.5 12.4 0.12 12.3 0.9 3.6 3 0 0 3 3 3 0 Zinc knuckle Atg8 PF02991.11 CEP07347.1 - 4.8e-52 174.2 0.2 5.6e-52 174.0 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CEP07347.1 - 3.4e-07 30.3 0.0 4.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PALP PF00291.20 CEP07349.1 - 2.4e-37 128.8 0.0 3.2e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CEP07349.1 - 1.1e-13 50.7 0.0 9.6e-09 34.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain Ribosomal_L2_C PF03947.13 CEP07349.1 - 1.9e-07 30.9 0.3 1.9e-07 30.9 0.2 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Glyco_tran_WecB PF03808.8 CEP07349.1 - 0.049 13.0 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DnaJ PF00226.26 CEP07350.1 - 1.9e-19 69.1 2.1 4.4e-19 67.9 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain TTL PF03133.10 CEP07351.1 - 1.5e-50 171.8 2.8 2e-50 171.4 1.9 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 CEP07351.1 - 2.8e-07 30.4 0.2 9.7e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP07351.1 - 0.0038 16.0 0.0 0.046 12.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Tape_meas_lam_C PF09718.5 CEP07351.1 - 0.087 12.7 0.3 3 7.7 0.1 2.5 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) SIR2 PF02146.12 CEP07351.1 - 0.15 11.7 0.5 0.66 9.6 0.1 2.3 2 1 1 3 3 3 0 Sir2 family MFS_1 PF07690.11 CEP07352.1 - 9.1e-26 90.3 42.8 9.1e-26 90.3 29.7 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP07352.1 - 4.9e-11 41.8 1.9 4.9e-11 41.8 1.3 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CEP07352.1 - 1.4e-06 26.8 21.3 3.5e-06 25.5 14.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-C2HC_2 PF13913.1 CEP07353.1 - 0.034 13.7 0.7 0.052 13.2 0.5 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type BTB_2 PF02214.17 CEP07354.1 - 1.7e-18 66.6 0.1 3.9e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 CEP07354.1 - 0.031 14.2 0.3 0.71 9.8 0.0 2.9 4 0 0 4 4 4 0 BTB/POZ domain DUF1675 PF07897.6 CEP07354.1 - 1.7 8.4 6.4 2.8 7.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) HIG_1_N PF04588.8 CEP07355.1 - 9.3e-14 50.9 8.1 8.5e-13 47.8 5.6 2.0 1 1 0 1 1 1 1 Hypoxia induced protein conserved region DUF1270 PF06900.6 CEP07355.1 - 0.1 12.7 0.1 4.9 7.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) FtsJ PF01728.14 CEP07356.1 - 4.5e-36 124.5 0.0 7.1e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase SYF2 PF08231.7 CEP07356.1 - 2.3 8.2 10.9 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 SYF2 splicing factor TPR_11 PF13414.1 CEP07357.1 - 1.3e-51 172.1 32.3 4.8e-16 58.1 4.6 5.6 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 CEP07357.1 - 2.4e-38 128.1 35.5 2.2e-08 33.3 0.2 8.7 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 CEP07357.1 - 1.5e-32 108.8 29.3 3.5e-05 23.3 0.1 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 CEP07357.1 - 3.9e-30 103.8 15.5 2.1e-09 37.7 0.7 6.6 5 2 2 7 7 6 5 Tetratricopeptide repeat DnaJ PF00226.26 CEP07357.1 - 3.5e-28 97.1 2.2 3.5e-28 97.1 1.6 2.5 3 0 0 3 3 1 1 DnaJ domain TPR_19 PF14559.1 CEP07357.1 - 9.2e-19 67.5 25.2 1.4e-05 25.3 0.0 6.5 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 CEP07357.1 - 6.4e-15 54.3 12.8 0.0016 18.9 0.0 8.3 4 3 3 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP07357.1 - 2.1e-13 49.2 30.8 0.01 15.9 0.8 9.2 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 CEP07357.1 - 4.7e-13 48.8 30.2 5.5e-05 23.0 0.4 7.5 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_9 PF13371.1 CEP07357.1 - 3e-09 36.6 6.6 0.06 13.2 0.0 5.0 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEP07357.1 - 4.1e-09 35.5 27.9 1.9 8.4 0.4 8.9 8 1 1 9 9 8 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEP07357.1 - 2.2e-07 30.6 14.1 0.18 11.6 0.0 6.4 5 2 2 7 7 7 3 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CEP07357.1 - 5.3e-07 29.6 19.8 0.28 11.7 0.1 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEP07357.1 - 2.5e-05 23.7 16.4 0.44 10.4 0.1 7.4 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP07357.1 - 0.0003 20.6 21.6 1 9.3 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CEP07357.1 - 0.00079 19.6 11.3 0.091 12.9 0.1 3.6 2 1 1 3 3 3 2 Alkyl sulfatase dimerisation Phage_term_smal PF05944.7 CEP07357.1 - 0.062 12.9 1.0 4.8 6.8 0.0 2.9 2 1 1 3 3 3 0 Phage small terminase subunit TPR_3 PF07720.7 CEP07357.1 - 0.081 12.7 23.1 0.094 12.5 0.6 7.1 8 1 1 9 9 9 0 Tetratricopeptide repeat DUF3856 PF12968.2 CEP07357.1 - 0.088 12.6 6.0 4.9 6.9 0.1 4.7 3 2 2 5 5 5 0 Domain of Unknown Function (DUF3856) MIT PF04212.13 CEP07357.1 - 0.19 11.6 22.5 0.6 10.0 1.6 5.1 4 2 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3463 PF11946.3 CEP07360.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Myb_DNA-bind_6 PF13921.1 CEP07361.1 - 0.0013 18.7 0.6 0.0034 17.4 0.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP07361.1 - 0.11 12.5 0.4 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Aa_trans PF01490.13 CEP07362.1 - 3.4e-91 305.7 29.1 4e-91 305.5 20.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CEP07362.1 - 1.8e-09 36.9 17.7 1.8e-09 36.9 12.2 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Dimer_Tnp_hAT PF05699.9 CEP07362.1 - 0.13 11.9 0.7 0.42 10.2 0.5 1.9 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Ost4 PF10215.4 CEP07362.1 - 0.74 9.3 8.1 0.13 11.8 1.0 3.1 2 0 0 2 2 2 0 Oligosaccaryltransferase Polysacc_deac_1 PF01522.16 CEP07364.1 - 1.1e-29 102.5 0.1 1.9e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP07364.1 - 0.0017 17.3 0.0 0.0051 15.7 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 MafB19-deam PF14437.1 CEP07364.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 MafB19-like deaminase L51_S25_CI-B8 PF05047.11 CEP07365.1 - 3.5e-09 36.2 0.1 5.2e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MRP_L53 PF10780.4 CEP07365.1 - 0.023 14.6 0.0 3.7 7.6 0.0 2.4 1 1 1 2 2 2 0 39S ribosomal protein L53/MRP-L53 CAML PF14963.1 CEP07366.1 - 0.13 11.5 0.4 0.2 11.0 0.3 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand GET2 PF08690.5 CEP07366.1 - 0.22 10.7 8.6 0.16 11.2 1.9 2.2 1 1 1 2 2 2 0 GET complex subunit GET2 AD PF09793.4 CEP07367.1 - 2.5e-25 88.1 0.0 4e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain PAS_9 PF13426.1 CEP07367.1 - 0.042 14.2 0.0 0.33 11.3 0.0 2.4 3 0 0 3 3 3 0 PAS domain Gemin6 PF06372.7 CEP07367.1 - 0.067 12.5 0.0 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Gemin6 protein Mito_carr PF00153.22 CEP07368.1 - 1.4e-60 200.9 5.8 1.7e-22 78.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 CEP07368.1 - 0.017 15.0 0.0 2.9 7.8 0.0 2.7 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Aa_trans PF01490.13 CEP07369.1 - 2e-61 207.7 24.7 2.3e-61 207.5 17.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CEP07369.1 - 3.9e-09 35.5 32.6 8e-09 34.5 22.6 1.5 1 1 0 1 1 1 1 Amino acid permease RNase_P_p30 PF01876.11 CEP07370.1 - 4.4e-36 123.3 0.2 7.6e-36 122.5 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit p30 PTS_IIB PF02302.12 CEP07370.1 - 0.041 14.3 0.5 15 6.1 0.0 3.1 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit DDE_3 PF13358.1 CEP07372.1 - 1.5e-27 96.1 0.0 2.9e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP07372.1 - 0.0056 16.2 0.2 0.014 15.0 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DUF3296 PF11726.3 CEP07372.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) rve PF00665.21 CEP07372.1 - 0.079 13.0 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain zinc_ribbon_2 PF13240.1 CEP07374.1 - 0.0046 16.4 5.7 1.3 8.5 0.0 4.1 4 0 0 4 4 4 1 zinc-ribbon domain Ribosomal_L32p PF01783.18 CEP07374.1 - 0.012 15.8 11.3 0.29 11.3 2.3 3.3 2 1 2 4 4 4 0 Ribosomal L32p protein family UPF0167 PF03691.9 CEP07374.1 - 0.015 14.6 5.5 0.073 12.4 0.4 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0167) DZR PF12773.2 CEP07374.1 - 0.019 14.7 12.9 0.3 10.9 0.8 3.5 2 2 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 CEP07374.1 - 0.019 14.1 10.1 0.54 9.5 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.14 CEP07374.1 - 0.11 12.1 14.1 3.6 7.3 0.5 3.4 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-CCHC PF00098.18 CEP07374.1 - 0.18 11.7 0.3 0.18 11.7 0.2 3.7 4 0 0 4 4 4 0 Zinc knuckle zf-C4_Topoisom PF01396.14 CEP07374.1 - 0.19 11.2 9.0 1.4 8.4 0.2 4.0 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger DUF164 PF02591.10 CEP07374.1 - 0.29 10.9 6.8 0.63 9.9 0.1 3.8 4 0 0 4 4 4 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.5 CEP07374.1 - 0.3 11.0 13.4 0.69 9.9 0.8 4.4 3 2 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CEP07374.1 - 0.33 10.8 14.7 0.54 10.1 0.2 4.0 3 1 1 4 4 4 0 Transposase zinc-ribbon domain Prok-RING_1 PF14446.1 CEP07374.1 - 0.34 10.6 13.3 4.8 7.0 0.1 4.5 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 YhfH PF14149.1 CEP07374.1 - 0.54 10.0 4.4 49 3.8 0.0 3.3 3 0 0 3 3 3 0 YhfH-like protein zf-H2C2_2 PF13465.1 CEP07374.1 - 0.6 10.5 9.1 13 6.2 0.3 4.3 4 1 0 4 4 4 0 Zinc-finger double domain zf-HYPF PF07503.7 CEP07374.1 - 0.66 9.4 6.1 5.7 6.4 0.0 3.8 4 0 0 4 4 4 0 HypF finger TF_Zn_Ribbon PF08271.7 CEP07374.1 - 1.5 8.2 4.8 39 3.6 0.2 3.5 3 0 0 3 3 3 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.7 CEP07374.1 - 1.8 8.4 5.1 8.9 6.1 0.1 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF1272 PF06906.6 CEP07374.1 - 2.5 8.0 6.0 14 5.5 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1272) GFA PF04828.9 CEP07374.1 - 3.1 7.8 9.8 4.3 7.3 1.3 3.3 1 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-Di19 PF05605.7 CEP07374.1 - 4.5 7.4 12.9 13 6.0 0.7 4.2 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF1451 PF07295.6 CEP07374.1 - 4.9 6.9 6.6 10 5.9 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1451) zf-NADH-PPase PF09297.6 CEP07374.1 - 8.9 5.9 8.6 13 5.4 0.1 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Grp1_Fun34_YaaH PF01184.14 CEP07375.1 - 1.9e-70 236.4 15.0 2.4e-70 236.1 10.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glycos_transf_2 PF00535.21 CEP07376.1 - 0.0013 18.4 0.3 0.015 14.9 0.2 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_hydro_47 PF01532.15 CEP07377.1 - 1.8e-128 429.0 0.6 2.1e-128 428.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.6 CEP07377.1 - 0.057 12.4 0.0 0.25 10.3 0.0 2.0 2 1 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) RRM_1 PF00076.17 CEP07378.1 - 9.2e-19 66.8 0.0 1.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07378.1 - 3.4e-14 52.5 0.0 6.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07378.1 - 1.5e-07 31.1 0.0 2.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CEP07378.1 - 8.4e-07 29.3 8.0 8.4e-07 29.3 5.5 4.2 3 2 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 tRNA_int_end_N2 PF12928.2 CEP07379.1 - 1.5e-07 30.7 0.0 2.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 CEP07379.1 - 0.0001 21.8 0.0 0.00047 19.6 0.0 2.0 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain HCV_NS5a_C PF12941.2 CEP07379.1 - 1.2 8.6 3.8 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region zf-CCHC PF00098.18 CEP07380.1 - 1.5e-47 157.2 53.7 6.9e-08 32.0 2.3 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CEP07380.1 - 9.3e-10 38.0 41.6 0.12 12.0 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CEP07380.1 - 8.1e-08 31.8 43.6 0.07 12.8 0.6 7.1 1 1 6 7 7 7 7 Zinc knuckle Nucleoplasmin PF03066.10 CEP07380.1 - 0.022 14.2 1.6 0.031 13.7 1.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CEP07380.1 - 0.84 9.9 9.9 0.39 11.0 5.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NinE PF05322.6 CEP07380.1 - 4.8 7.0 7.4 23 4.8 0.7 3.2 3 0 0 3 3 3 0 NINE Protein zf-CCHC_2 PF13696.1 CEP07380.1 - 6.2 6.4 42.7 0.33 10.5 0.3 6.9 4 2 3 7 7 7 0 Zinc knuckle Kelch_4 PF13418.1 CEP07381.1 - 2e-18 65.8 16.1 2.3e-06 27.2 0.0 7.3 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP07381.1 - 1.4e-16 60.1 9.9 4.2e-05 23.5 0.1 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 CEP07381.1 - 5.1e-14 51.5 4.2 0.0019 17.7 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CEP07381.1 - 2e-11 43.5 4.4 6.9e-05 22.7 0.0 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 CEP07381.1 - 6.5e-11 41.9 12.8 0.018 15.2 0.0 6.3 4 1 2 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CEP07381.1 - 4.3e-08 32.6 1.6 0.46 10.3 0.0 5.7 5 1 0 5 5 5 2 Kelch motif Romo1 PF10247.4 CEP07381.1 - 0.0081 16.3 1.6 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 Sugar_tr PF00083.19 CEP07382.1 - 2.6e-95 319.6 21.7 1.3e-94 317.3 15.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP07382.1 - 7.8e-31 107.0 48.2 2e-27 95.8 12.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.1 CEP07382.1 - 0.097 12.7 0.3 0.45 10.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Myb_Cef PF11831.3 CEP07383.1 - 5.6e-41 140.2 5.3 5.6e-41 140.2 3.7 3.6 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 CEP07383.1 - 2.1e-22 78.9 5.0 7.2e-12 45.1 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP07383.1 - 3.3e-21 75.1 8.2 2.3e-14 53.2 2.7 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 CEP07383.1 - 0.0093 15.4 0.8 0.17 11.4 0.0 3.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain DUF3348 PF11828.3 CEP07384.1 - 0.0035 16.7 0.7 0.0051 16.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) Exonuc_VII_L PF02601.10 CEP07384.1 - 0.86 8.7 6.9 2.3 7.3 2.0 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.5 CEP07384.1 - 1.3 9.1 5.0 2.6 8.1 0.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Myb_DNA-binding PF00249.26 CEP07385.1 - 4.4e-12 45.8 0.8 1.1e-11 44.5 0.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain BAG PF02179.11 CEP07385.1 - 1.1e-11 44.6 1.3 1.1e-11 44.6 0.9 2.5 2 0 0 2 2 2 1 BAG domain Myb_DNA-bind_6 PF13921.1 CEP07385.1 - 1.1e-09 38.2 0.5 6.3e-09 35.8 0.4 2.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ubiquitin_2 PF14560.1 CEP07385.1 - 0.00022 21.3 0.0 0.0011 19.1 0.0 2.2 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 CEP07385.1 - 0.00096 18.5 0.2 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Sulfotransfer_3 PF13469.1 CEP07386.1 - 0.022 15.7 0.0 0.06 14.2 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family DUF1924 PF09086.6 CEP07386.1 - 0.03 14.3 0.3 0.99 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) DUF413 PF04219.7 CEP07386.1 - 0.065 12.9 0.1 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF Paf1 PF03985.8 CEP07387.1 - 2e-37 129.0 0.6 2.5e-37 128.6 0.4 1.0 1 0 0 1 1 1 1 Paf1 Cofilin_ADF PF00241.15 CEP07387.1 - 0.093 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein UPF0139 PF03669.8 CEP07388.1 - 4.7e-08 32.4 0.0 6.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF4311 PF14188.1 CEP07388.1 - 0.037 13.5 0.1 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) p450 PF00067.17 CEP07389.1 - 3.9e-75 253.1 0.0 5.2e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MAGE PF01454.14 CEP07390.1 - 4.5e-36 124.0 1.6 6.1e-36 123.6 1.1 1.2 1 0 0 1 1 1 1 MAGE family Inhibitor_I71 PF12628.2 CEP07390.1 - 0.046 13.3 3.2 0.088 12.4 2.3 1.4 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Glyco_hydro_67N PF03648.9 CEP07390.1 - 0.053 13.5 1.7 0.094 12.7 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DUF221 PF02714.10 CEP07391.1 - 1.3e-69 234.5 29.3 4.4e-69 232.8 20.3 1.9 1 1 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEP07391.1 - 8.2e-35 119.6 1.4 8.2e-35 119.6 1.0 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CEP07391.1 - 2.2e-12 47.2 0.0 5.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) AIF_C PF14721.1 CEP07392.1 - 8.6e-46 155.4 0.2 2e-45 154.2 0.1 1.7 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.9 CEP07392.1 - 6.3e-25 88.2 0.8 5.1e-23 81.9 0.5 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP07392.1 - 1.6e-13 50.8 4.6 1.8e-11 44.2 0.1 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP07392.1 - 2.2e-10 39.9 5.9 1.4e-05 24.2 0.1 3.6 3 1 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEP07392.1 - 2.3e-10 40.9 0.5 4e-06 27.0 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP07392.1 - 2.5e-09 36.5 1.0 2.7e-05 23.2 0.0 3.3 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 CEP07392.1 - 2e-07 30.9 2.1 0.024 14.3 0.1 4.2 3 1 1 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.9 CEP07392.1 - 1.3e-06 27.1 0.3 0.017 13.6 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 CEP07392.1 - 2e-06 26.9 0.1 7.5e-05 21.7 0.0 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 CEP07392.1 - 0.0048 16.0 0.2 0.04 12.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 CEP07392.1 - 0.04 12.5 3.1 9.8 4.6 0.0 3.1 2 1 1 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.15 CEP07392.1 - 0.11 12.6 0.6 0.88 9.6 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CEP07392.1 - 0.26 11.3 1.5 28 4.8 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DUF2360 PF10152.4 CEP07392.1 - 0.29 11.4 3.6 3.9 7.7 0.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PUF PF00806.14 CEP07393.1 - 1.6e-68 222.4 13.5 4.5e-09 35.3 0.0 8.8 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Zip PF02535.17 CEP07393.1 - 0.58 9.1 3.7 1.2 8.1 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DDE_3 PF13358.1 CEP07394.1 - 1.6e-08 34.4 0.0 5.5e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Peptidase_M16 PF00675.15 CEP07394.1 - 0.033 13.9 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) HTH_28 PF13518.1 CEP07395.1 - 0.00021 21.2 0.1 0.0023 17.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.14 CEP07395.1 - 0.00052 19.6 0.4 0.00059 19.4 0.3 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 CEP07395.1 - 0.00076 19.6 0.3 0.0017 18.4 0.1 1.6 1 1 1 2 2 2 1 Winged helix-turn helix KorB PF08535.5 CEP07395.1 - 0.0023 18.0 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 KorB domain HTH_38 PF13936.1 CEP07395.1 - 0.0023 17.4 0.3 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_15 PF12324.3 CEP07395.1 - 0.01 15.5 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase HTH_Tnp_Tc3_2 PF01498.13 CEP07395.1 - 0.011 15.7 0.1 0.028 14.4 0.0 1.8 2 1 0 2 2 2 0 Transposase HTH_23 PF13384.1 CEP07395.1 - 0.011 15.3 0.1 0.039 13.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain IF2_N PF04760.10 CEP07395.1 - 0.016 14.8 0.1 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_17 PF12728.2 CEP07395.1 - 0.024 14.8 0.1 0.055 13.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.1 CEP07395.1 - 0.052 12.9 0.2 0.14 11.5 0.0 1.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r3 PF04539.11 CEP07395.1 - 0.061 13.2 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 region 3 Sigma70_r4_2 PF08281.7 CEP07395.1 - 0.1 12.1 0.5 0.75 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_r4 PF04545.11 CEP07395.1 - 0.12 11.7 0.1 0.33 10.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-70, region 4 Complex1_LYR PF05347.10 CEP07398.1 - 0.0045 16.7 2.0 0.063 13.0 0.4 2.6 3 0 0 3 3 3 1 Complex 1 protein (LYR family) ELYS PF13934.1 CEP07398.1 - 0.018 14.7 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex assembly SMC_Nse1 PF07574.8 CEP07398.1 - 0.064 12.8 0.2 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Complex1_LYR_1 PF13232.1 CEP07398.1 - 0.65 10.2 4.4 10 6.4 0.9 2.5 3 0 0 3 3 3 0 Complex1_LYR-like LRR_6 PF13516.1 CEP07399.1 - 9.3e-08 31.3 6.8 0.027 14.5 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 CEP07399.1 - 2.3e-07 30.2 2.8 0.00012 21.5 0.1 3.6 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP07399.1 - 4.8e-06 26.2 9.2 0.00016 21.3 0.5 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CEP07399.1 - 0.00063 19.4 4.7 4.4 7.7 0.1 5.1 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CEP07399.1 - 0.00079 19.2 4.8 6.4 7.4 0.0 5.7 6 0 0 6 6 6 1 Leucine rich repeat F-box-like PF12937.2 CEP07399.1 - 0.0048 16.5 1.4 0.007 16.0 0.2 1.8 2 0 0 2 2 2 1 F-box-like Y_phosphatase3 PF13350.1 CEP07400.1 - 1.5e-41 142.3 0.0 4.2e-41 140.9 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CEP07400.1 - 2.7e-10 40.2 0.1 6.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Abhydrolase_5 PF12695.2 CEP07400.1 - 6.5e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP07400.1 - 2e-07 31.1 0.1 5.5e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase PF00102.22 CEP07400.1 - 0.00021 20.6 0.0 0.00054 19.3 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CEP07400.1 - 0.072 12.6 0.8 0.34 10.4 0.0 2.3 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Peptidase_S9 PF00326.16 CEP07400.1 - 0.12 11.5 0.4 0.26 10.4 0.3 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family WD40 PF00400.27 CEP07401.1 - 1e-10 41.0 18.0 1.4e-06 27.9 0.2 5.2 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 CEP07401.1 - 0.048 13.3 0.0 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CEP07401.1 - 0.15 10.2 0.0 0.32 9.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain FlgN PF05130.7 CEP07402.1 - 0.074 13.2 0.5 0.27 11.4 0.2 1.9 1 1 1 2 2 2 0 FlgN protein Osmo_CC PF08946.5 CEP07402.1 - 0.2 11.7 10.5 0.64 10.0 0.5 3.3 2 1 1 3 3 3 0 Osmosensory transporter coiled coil rve PF00665.21 CEP07403.1 - 3.4e-22 78.8 0.0 5.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP07403.1 - 0.0021 17.5 0.0 0.0071 15.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CEP07403.1 - 0.018 14.9 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 DDE domain APC_CDC26 PF10471.4 CEP07404.1 - 1 10.1 10.6 1.6 9.5 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Sugarporin_N PF11471.3 CEP07404.1 - 6 6.6 8.0 1.4 8.5 2.3 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension AAA_12 PF13087.1 CEP07406.1 - 1.5e-62 210.5 0.0 3.7e-62 209.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEP07406.1 - 4.1e-61 206.5 0.5 1.2e-60 205.0 0.4 1.8 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.2 CEP07406.1 - 1.3e-58 198.7 12.2 2.2e-58 197.9 8.4 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.1 CEP07406.1 - 5.4e-13 48.5 0.1 1.7e-12 46.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 CEP07406.1 - 6.4e-09 35.5 0.5 4e-06 26.3 0.4 3.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 CEP07406.1 - 7.9e-09 35.3 0.2 3.2e-06 26.8 0.1 2.8 2 0 0 2 2 2 2 AAA domain DEAD PF00270.24 CEP07406.1 - 8.8e-05 22.0 0.5 0.0058 16.1 0.8 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 CEP07406.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CEP07406.1 - 0.021 14.9 0.0 0.087 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CEP07406.1 - 0.022 14.6 0.0 0.078 12.8 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ogr_Delta PF04606.7 CEP07407.1 - 2.8 7.6 5.1 0.39 10.4 0.4 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.1 CEP07408.1 - 0.0089 16.3 4.0 0.18 12.1 0.7 2.7 2 1 0 2 2 2 1 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 CEP07408.1 - 0.016 15.1 3.3 2.2 8.2 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain HNH PF01844.18 CEP07408.1 - 0.036 13.9 4.0 3.8 7.4 0.2 3.4 3 0 0 3 3 3 0 HNH endonuclease HATPase_c_4 PF13749.1 CEP07408.1 - 0.071 12.9 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal DUF164 PF02591.10 CEP07408.1 - 0.071 12.9 4.0 7.5 6.4 0.3 3.5 3 0 0 3 3 3 0 Putative zinc ribbon domain zf-CCHC PF00098.18 CEP07408.1 - 0.69 9.9 6.3 7.4 6.6 0.1 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-RING_3 PF14369.1 CEP07408.1 - 2.4 8.2 8.1 27 4.8 0.1 3.9 3 1 0 3 3 3 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 CEP07408.1 - 2.6 7.9 9.5 7.6 6.4 0.4 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain UPF0278 PF08745.6 CEP07409.1 - 0.012 14.8 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 UPF0278 family Ubie_methyltran PF01209.13 CEP07410.1 - 1.5e-79 266.4 0.2 5.8e-79 264.4 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Synaptobrevin PF00957.16 CEP07410.1 - 1.5e-30 104.6 0.9 1.5e-30 104.6 0.6 2.2 3 0 0 3 3 3 1 Synaptobrevin Methyltransf_11 PF08241.7 CEP07410.1 - 1.1e-11 45.1 0.7 2.3e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP07410.1 - 2.7e-11 43.2 0.3 7e-11 41.9 0.0 1.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP07410.1 - 1.2e-09 38.0 0.3 6.4e-09 35.7 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP07410.1 - 9e-08 32.5 1.1 1.1e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP07410.1 - 1.2e-05 25.6 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP07410.1 - 1.7e-05 25.3 0.0 5.9e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CEP07410.1 - 0.00081 18.8 0.0 0.0021 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 CEP07410.1 - 0.0066 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_28 PF02636.12 CEP07410.1 - 0.016 14.6 0.4 0.042 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 CEP07410.1 - 0.025 14.5 0.0 0.081 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Melibiase PF02065.13 CEP07411.1 - 7.8e-15 54.4 0.3 1.4e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 CEP07411.1 - 1.2e-08 34.2 0.1 1.8e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GHL6 PF14871.1 CEP07411.1 - 0.024 14.6 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Raffinose_syn PF05691.7 CEP07411.1 - 0.043 11.3 0.1 0.064 10.7 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 ACOX PF01756.14 CEP07412.1 - 2.1e-51 173.9 0.0 6.9e-51 172.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CEP07412.1 - 4.9e-14 51.5 0.6 1.3e-13 50.1 0.4 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CEP07412.1 - 7.8e-13 48.8 0.0 2.3e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CEP07412.1 - 1.4e-08 34.9 0.6 6.7e-08 32.7 0.4 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain KH_1 PF00013.24 CEP07413.1 - 1.6e-10 40.4 0.0 5.5e-06 25.9 0.0 2.7 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CEP07413.1 - 2e-08 33.6 0.2 7.1e-06 25.5 0.0 2.6 2 0 0 2 2 2 2 KH domain Retrotrans_gag PF03732.12 CEP07415.1 - 0.0031 17.5 0.5 0.0088 16.0 0.4 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein DUF713 PF05218.9 CEP07415.1 - 0.014 15.1 2.4 0.04 13.6 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF713) UBN2_2 PF14227.1 CEP07415.1 - 0.021 14.3 1.3 0.021 14.3 0.9 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type GATA PF00320.22 CEP07415.1 - 0.25 10.7 2.6 0.59 9.5 1.8 1.7 1 0 0 1 1 1 0 GATA zinc finger HTH_28 PF13518.1 CEP07416.1 - 1.3e-06 28.3 0.0 1.6e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP07416.1 - 4.5e-06 26.7 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP07416.1 - 3.5e-05 23.3 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Fe_dep_repress PF01325.14 CEP07416.1 - 0.00043 20.1 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Terminase_5 PF06056.7 CEP07416.1 - 0.0085 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) LZ_Tnp_IS481 PF13011.1 CEP07416.1 - 0.012 15.8 0.0 0.013 15.8 0.0 1.1 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 MarR_2 PF12802.2 CEP07416.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_7 PF02796.10 CEP07416.1 - 0.02 14.7 1.5 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase PAX PF00292.13 CEP07416.1 - 0.034 13.8 0.1 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 'Paired box' domain TrmB PF01978.14 CEP07416.1 - 0.045 13.4 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 CEP07416.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_L35p PF01632.14 CEP07416.1 - 0.13 12.2 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L35 Sigma70_r4 PF04545.11 CEP07416.1 - 0.14 11.4 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 zf-RVT PF13966.1 CEP07417.1 - 1.1e-07 32.0 1.0 2e-07 31.1 0.7 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF3007 PF11460.3 CEP07420.1 - 0.091 12.8 0.6 0.23 11.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) rve PF00665.21 CEP07421.1 - 3.9e-15 56.0 0.0 6.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP07421.1 - 0.0027 17.0 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 CEP07422.1 - 1.5e-16 60.3 0.1 3.5e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP07422.1 - 6.4e-10 39.4 0.1 6.8e-09 36.1 0.0 2.6 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP07422.1 - 2.5e-07 30.4 0.1 1.8e-06 27.6 0.0 2.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CEP07422.1 - 0.067 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Sugar_tr PF00083.19 CEP07424.1 - 1.1e-104 350.5 30.4 2.6e-102 342.7 21.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP07424.1 - 6.5e-26 90.8 27.5 6.5e-26 90.8 19.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CEP07424.1 - 0.00048 18.6 38.8 0.019 13.4 5.3 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein Helitron_like_N PF14214.1 CEP07425.1 - 4.6e-36 124.2 0.0 6.3e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDE_3 PF13358.1 CEP07426.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_S17 PF00366.15 CEP07427.1 - 4.2e-29 100.3 0.5 6.4e-29 99.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 GAS2 PF02187.12 CEP07428.1 - 1.1e-07 31.5 0.1 3.1e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Lactamase_B PF00753.22 CEP07429.1 - 1.9e-24 86.3 0.7 2.6e-24 85.9 0.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CEP07429.1 - 3.3e-06 26.7 0.2 4.7e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEP07429.1 - 4.9e-05 23.0 0.1 8.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AAA PF00004.24 CEP07430.1 - 4.9e-23 81.7 0.0 1.7e-22 80.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 CEP07430.1 - 5.1e-09 36.0 0.3 9.9e-09 35.0 0.2 1.5 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.7 CEP07430.1 - 1.2e-06 27.7 0.0 2.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CEP07430.1 - 1.2e-05 25.4 0.2 0.00013 22.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP07430.1 - 2.1e-05 25.2 0.0 8.4e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEP07430.1 - 0.00011 21.9 0.0 0.00025 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CEP07430.1 - 0.00031 20.4 0.1 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 CEP07430.1 - 0.0004 19.3 0.0 0.00072 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 CEP07430.1 - 0.00047 19.6 0.0 0.0021 17.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP07430.1 - 0.00068 19.6 0.0 0.0023 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 CEP07430.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CEP07430.1 - 0.0018 18.4 1.6 0.018 15.2 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.1 CEP07430.1 - 0.003 17.8 0.0 0.01 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CEP07430.1 - 0.003 16.7 0.1 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.1 CEP07430.1 - 0.0098 15.8 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CEP07430.1 - 0.012 15.8 0.2 0.037 14.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 CEP07430.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 CEP07430.1 - 0.022 14.3 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 CEP07430.1 - 0.026 13.4 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.18 CEP07430.1 - 0.032 14.1 0.1 0.097 12.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CEP07430.1 - 0.04 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 CEP07430.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CEP07430.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CEP07430.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.14 CEP07431.1 - 2.7e-13 49.9 0.9 7.3e-13 48.5 0.1 2.2 3 0 0 3 3 2 1 HMG (high mobility group) box SAM_1 PF00536.25 CEP07431.1 - 3.7e-12 46.2 0.0 6.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 CEP07431.1 - 4.6e-09 36.5 0.2 1.5e-08 34.8 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain HTH_29 PF13551.1 CEP07431.1 - 5.7e-08 32.8 0.1 1.6e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix SAM_2 PF07647.12 CEP07431.1 - 6.1e-08 32.3 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HTH_23 PF13384.1 CEP07431.1 - 1.9e-05 24.1 0.1 0.002 17.7 0.1 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP07431.1 - 2e-05 24.5 1.1 0.00042 20.2 0.6 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP07431.1 - 0.00011 22.9 0.1 0.00057 20.6 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain NCD1 PF04904.8 CEP07431.1 - 0.00035 20.2 0.3 0.0035 17.0 0.0 2.5 3 0 0 3 3 3 1 NAB conserved region 1 (NCD1) HTH_Tnp_ISL3 PF13542.1 CEP07431.1 - 0.012 14.7 0.2 0.058 12.5 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 CEP07431.1 - 0.014 15.6 0.2 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DEAD PF00270.24 CEP07432.1 - 4.8e-42 143.3 0.0 1.4e-39 135.3 0.0 3.4 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP07432.1 - 2.8e-26 91.1 0.0 7.4e-26 89.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP07432.1 - 0.00035 20.4 0.1 0.0027 17.5 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CEP07432.1 - 0.0023 17.9 0.1 0.019 14.9 0.0 2.5 3 0 0 3 3 3 1 Helicase C-terminal domain zf-CCHC PF00098.18 CEP07432.1 - 0.011 15.6 3.1 0.02 14.8 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEP07432.1 - 0.013 15.1 0.8 0.028 14.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 CEP07432.1 - 5.4 6.5 6.0 0.48 9.9 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle UCH PF00443.24 CEP07434.1 - 1.3e-40 139.2 0.0 1.7e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP07434.1 - 1.2e-11 44.6 0.0 4.5e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 CEP07435.1 - 2.1e-06 27.3 2.2 7.1e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Hira PF07569.6 CEP07435.1 - 0.061 12.5 0.5 1.8 7.7 0.0 2.7 2 1 1 3 3 3 0 TUP1-like enhancer of split N_methyl_3 PF13633.1 CEP07436.1 - 0.5 10.3 3.2 0.84 9.6 2.2 1.4 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation site Prefoldin_2 PF01920.15 CEP07438.1 - 9.2e-25 86.4 6.0 1e-24 86.2 4.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 CEP07438.1 - 0.00063 19.4 3.5 0.0009 18.8 2.4 1.2 1 0 0 1 1 1 1 IncA protein DUF2935 PF11155.3 CEP07438.1 - 0.00069 19.6 0.6 0.00088 19.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) BLOC1_2 PF10046.4 CEP07438.1 - 0.0041 17.2 4.6 0.055 13.6 0.3 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 UBN2 PF14223.1 CEP07438.1 - 0.0041 16.9 0.4 2.7 7.7 0.0 2.1 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type KaiC PF06745.8 CEP07438.1 - 0.0044 16.1 0.0 0.0061 15.7 0.0 1.2 1 1 0 1 1 1 1 KaiC GAS PF13851.1 CEP07438.1 - 0.0046 16.1 4.5 0.59 9.2 0.3 2.0 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DASH_Dad3 PF08656.5 CEP07438.1 - 0.0092 15.6 1.8 0.018 14.7 0.3 1.9 2 0 0 2 2 2 1 DASH complex subunit Dad3 TMF_TATA_bd PF12325.3 CEP07438.1 - 0.011 15.5 3.6 1.3 8.7 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DASH_Spc34 PF08657.5 CEP07438.1 - 0.013 15.1 2.1 0.013 15.1 1.5 1.9 1 1 1 2 2 2 0 DASH complex subunit Spc34 DUF342 PF03961.8 CEP07438.1 - 0.04 12.3 2.6 0.054 11.9 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Kinetocho_Slk19 PF12709.2 CEP07438.1 - 0.045 13.8 3.0 2.3 8.3 0.4 2.2 2 0 0 2 2 2 0 Central kinetochore-associated TMF_DNA_bd PF12329.3 CEP07438.1 - 0.054 13.3 1.2 0.054 13.3 0.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 CEP07438.1 - 0.056 13.7 1.3 0.095 13.0 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TBPIP PF07106.8 CEP07438.1 - 0.079 12.4 0.4 0.079 12.4 0.2 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 CEP07438.1 - 0.084 12.5 4.8 6.4 6.4 3.2 2.1 1 1 0 1 1 1 0 Prefoldin subunit Retrotrans_gag PF03732.12 CEP07438.1 - 0.094 12.8 0.3 2.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein TPR_MLP1_2 PF07926.7 CEP07438.1 - 0.14 11.8 3.6 0.37 10.5 0.2 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 CEP07438.1 - 0.15 11.8 4.0 0.27 11.0 0.6 2.0 2 0 0 2 2 2 0 Tropomyosin like DUF4200 PF13863.1 CEP07438.1 - 0.19 11.6 6.6 0.63 10.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Nnf1 PF03980.9 CEP07438.1 - 0.24 11.3 3.8 0.27 11.2 0.5 2.2 2 1 1 3 3 3 0 Nnf1 ERM PF00769.14 CEP07438.1 - 0.3 10.5 3.4 1.1 8.7 2.3 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fib_alpha PF08702.5 CEP07438.1 - 0.36 10.9 3.2 1.7 8.7 2.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin_3 PF13758.1 CEP07438.1 - 0.36 10.6 3.3 1.4 8.7 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit IFT57 PF10498.4 CEP07438.1 - 0.39 9.4 7.1 11 4.6 4.6 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DivIC PF04977.10 CEP07438.1 - 0.4 10.1 5.3 0.48 9.9 1.5 2.0 2 0 0 2 2 2 0 Septum formation initiator GrpE PF01025.14 CEP07438.1 - 0.47 9.9 4.4 7 6.1 0.4 2.0 2 0 0 2 2 2 0 GrpE DivIVA PF05103.8 CEP07438.1 - 0.65 10.0 6.5 0.15 12.1 0.5 2.0 2 0 0 2 2 2 0 DivIVA protein Seryl_tRNA_N PF02403.17 CEP07438.1 - 0.74 9.8 3.6 0.75 9.8 0.5 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.16 CEP07438.1 - 0.88 9.5 5.0 0.3 11.0 0.9 1.9 2 0 0 2 2 2 0 bZIP transcription factor Sod_Cu PF00080.15 CEP07439.1 - 1.8e-35 122.1 1.5 3.9e-35 121.0 1.1 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 CEP07439.1 - 2.6e-14 53.0 2.4 7.1e-14 51.7 0.0 2.6 3 0 0 3 3 3 1 Heavy-metal-associated domain Inhibitor_I9 PF05922.11 CEP07439.1 - 9.5e-08 32.5 0.2 1.5e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1939 PF09154.5 CEP07439.1 - 0.063 13.1 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) RL11D PF11088.3 CEP07439.1 - 0.24 11.2 2.4 0.18 11.6 0.3 1.9 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 DUF4629 PF15442.1 CEP07440.1 - 0.0042 17.2 15.4 0.006 16.7 10.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4629) Peptidase_S49_N PF08496.5 CEP07440.1 - 0.0091 15.7 4.8 0.013 15.3 3.4 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal NARP1 PF12569.3 CEP07440.1 - 0.021 13.5 4.2 0.023 13.4 2.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BLVR PF06375.6 CEP07440.1 - 0.082 12.7 9.6 0.12 12.2 6.6 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Arrestin_N PF00339.24 CEP07440.1 - 0.2 11.5 2.9 0.29 10.9 2.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Peroxin-13_N PF04088.8 CEP07440.1 - 0.3 11.0 1.5 0.49 10.3 1.0 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF3464 PF11947.3 CEP07440.1 - 0.46 9.9 4.5 0.8 9.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF3899 PF13038.1 CEP07440.1 - 0.46 10.6 2.4 0.99 9.6 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) RNase_H2-Ydr279 PF09468.5 CEP07440.1 - 2.6 7.1 12.0 3.8 6.6 8.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SR-25 PF10500.4 CEP07440.1 - 4.7 6.6 16.5 7.6 5.9 11.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ZZ PF00569.12 CEP07441.1 - 0.017 14.6 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Phlebovirus_G1 PF07243.6 CEP07441.1 - 0.029 12.5 3.5 0.032 12.4 2.4 1.0 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 zf-CCHC PF00098.18 CEP07441.1 - 0.047 13.6 0.4 0.091 12.7 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-B_box PF00643.19 CEP07441.1 - 0.11 12.3 0.9 0.19 11.6 0.6 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-CCHC_5 PF14787.1 CEP07441.1 - 1.8 8.1 5.6 0.54 9.8 1.3 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DNA_pol_phi PF04931.8 CEP07442.1 - 5.2e-69 232.9 22.8 8.6e-69 232.1 15.8 1.4 1 0 0 1 1 1 1 DNA polymerase phi DUF4203 PF13886.1 CEP07444.1 - 8.8e-14 51.4 40.0 1.2e-13 51.0 27.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) ABC_tran PF00005.22 CEP07445.1 - 1.3e-36 125.8 0.1 9.6e-19 68.0 0.0 2.9 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CEP07445.1 - 4.7e-15 54.8 5.6 1.2e-14 53.5 3.9 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CEP07445.1 - 2.6e-13 50.6 16.3 0.00089 19.3 0.2 4.8 3 2 2 5 5 4 4 AAA domain SMC_N PF02463.14 CEP07445.1 - 1.2e-12 47.6 3.6 0.00011 21.5 0.6 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 CEP07445.1 - 2.5e-08 33.1 2.6 2.5e-08 33.1 1.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 CEP07445.1 - 8.6e-07 28.4 0.1 0.051 13.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 CEP07445.1 - 4.7e-06 25.9 7.3 1.9 7.4 1.0 4.2 3 1 1 4 4 4 2 AAA ATPase domain Fer4_6 PF12837.2 CEP07445.1 - 5.3e-06 26.0 11.8 1e-05 25.1 1.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_17 PF13207.1 CEP07445.1 - 4.9e-05 24.1 0.6 0.48 11.2 0.0 2.8 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEP07445.1 - 6.7e-05 22.1 4.4 0.055 12.6 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA PF00004.24 CEP07445.1 - 0.00044 20.4 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEP07445.1 - 0.0005 20.1 0.2 0.063 13.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CEP07445.1 - 0.0006 20.1 0.1 0.34 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 CEP07445.1 - 0.00069 19.3 2.4 0.00069 19.3 1.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.10 CEP07445.1 - 0.0014 17.3 0.0 0.092 11.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_7 PF12838.2 CEP07445.1 - 0.0016 18.7 1.8 0.0016 18.7 1.2 1.9 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 CEP07445.1 - 0.0021 17.8 11.8 0.0039 17.0 8.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 CEP07445.1 - 0.0021 17.5 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E Thymidylate_kin PF02223.12 CEP07445.1 - 0.0023 17.3 0.2 4.8 6.5 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase Miro PF08477.8 CEP07445.1 - 0.0024 18.3 0.1 0.41 11.1 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein AAA_22 PF13401.1 CEP07445.1 - 0.0027 17.8 0.2 0.38 10.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Fer4_10 PF13237.1 CEP07445.1 - 0.0037 17.0 1.2 0.0037 17.0 0.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain MobB PF03205.9 CEP07445.1 - 0.0037 16.9 0.6 0.52 10.0 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 CEP07445.1 - 0.0042 16.9 0.1 0.88 9.5 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CEP07445.1 - 0.0046 16.8 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.1 CEP07445.1 - 0.0047 17.6 5.7 0.0061 17.2 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 CEP07445.1 - 0.0055 16.9 11.9 0.016 15.4 8.3 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.2 CEP07445.1 - 0.0061 17.0 5.0 0.0061 17.0 3.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.17 CEP07445.1 - 0.0067 16.5 0.1 3.3 7.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 CEP07445.1 - 0.01 15.5 2.3 0.43 10.2 0.0 3.5 3 1 1 4 4 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CEP07445.1 - 0.012 15.2 1.5 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.17 CEP07445.1 - 0.024 14.0 2.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CEP07445.1 - 0.037 13.4 0.1 6.5 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CEP07445.1 - 0.042 13.7 0.0 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.8 CEP07445.1 - 0.055 12.3 0.1 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ArgK PF03308.11 CEP07445.1 - 0.058 12.1 0.1 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 CEP07445.1 - 0.069 12.5 0.9 4.4 6.6 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 CEP07445.1 - 0.076 13.3 0.1 0.076 13.3 0.1 2.9 2 2 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CEP07445.1 - 0.082 12.5 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CEP07445.1 - 0.12 12.3 0.5 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CEP07445.1 - 0.12 11.2 0.0 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 CEP07445.1 - 0.14 11.6 0.1 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CEP07445.1 - 0.15 11.1 0.1 2.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 CEP07445.1 - 0.18 11.2 0.2 11 5.4 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_14 PF13173.1 CEP07445.1 - 0.19 11.6 0.9 14 5.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 CEP07445.1 - 0.19 12.1 13.7 0.044 14.1 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_13 PF13166.1 CEP07445.1 - 0.47 8.8 0.0 0.47 8.8 0.0 2.1 3 0 0 3 3 2 0 AAA domain Fer4_8 PF13183.1 CEP07445.1 - 0.7 9.9 10.4 0.11 12.5 1.0 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 CEP07445.1 - 3.3 8.3 8.1 0.11 13.0 0.7 2.2 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_18 PF13746.1 CEP07445.1 - 4.6 7.7 10.3 0.22 11.9 2.3 2.1 1 1 0 2 2 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 CEP07445.1 - 5.3 7.4 12.2 0.11 12.8 0.8 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Sec20 PF03908.8 CEP07446.1 - 1.1e-17 63.5 1.8 1.1e-17 63.5 1.2 2.5 2 1 0 2 2 2 1 Sec20 HOASN PF14515.1 CEP07446.1 - 0.0057 17.0 0.3 0.016 15.5 0.2 1.8 1 0 0 1 1 1 1 Haem-oxygenase-associated N-terminal helices BatA PF07584.6 CEP07446.1 - 0.02 15.0 0.4 0.064 13.4 0.3 1.9 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal NnrU PF07298.6 CEP07446.1 - 0.053 12.8 0.3 0.083 12.2 0.2 1.2 1 0 0 1 1 1 0 NnrU protein CCDC-167 PF15188.1 CEP07446.1 - 0.061 13.2 3.3 0.23 11.4 2.2 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 PilJ PF13675.1 CEP07446.1 - 0.57 10.5 6.1 0.73 10.1 0.2 2.9 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Aminotran_1_2 PF00155.16 CEP07447.1 - 6.3e-77 258.9 0.0 7.9e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CEP07447.1 - 2.5e-06 26.0 0.0 4.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CEP07447.1 - 7.1e-05 21.7 0.0 0.00016 20.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CEP07447.1 - 0.00022 20.4 0.0 0.00042 19.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3405 PF11885.3 CEP07447.1 - 0.016 13.5 0.3 0.023 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Scm3 PF10384.4 CEP07447.1 - 0.34 10.4 1.6 5.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Centromere protein Scm3 Pex24p PF06398.6 CEP07448.1 - 2.4e-17 62.7 20.7 4.5e-17 61.8 14.3 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 CEP07448.1 - 0.087 10.9 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Lzipper-MIP1 PF14389.1 CEP07452.1 - 0.0065 16.5 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 CEP07452.1 - 0.035 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.1 CEP07452.1 - 0.32 11.4 3.1 0.25 11.8 0.4 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-C4H2 PF10146.4 CEP07452.1 - 0.46 10.4 3.7 0.23 11.4 0.8 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein zf-DHHC PF01529.15 CEP07453.1 - 1.7 7.9 18.1 0.019 14.3 6.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Choline_kinase PF01633.15 CEP07454.1 - 6.8e-65 218.5 0.0 9.2e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CEP07454.1 - 6.1e-16 58.8 0.0 8.1e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CEP07454.1 - 0.025 13.7 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase UvrD_C PF13361.1 CEP07455.1 - 9.5e-53 179.8 0.7 3.6e-23 82.5 0.0 3.4 2 1 1 3 3 3 3 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CEP07455.1 - 5.6e-30 104.7 3.9 5.6e-30 104.7 2.7 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CEP07455.1 - 6.9e-10 38.9 0.0 3.1e-09 36.8 0.0 2.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Pkinase PF00069.20 CEP07456.1 - 2.2e-54 184.3 0.0 4e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CRAL_TRIO PF00650.15 CEP07456.1 - 3.4e-42 143.6 1.1 1.4e-41 141.6 0.0 2.3 2 0 0 2 2 2 1 CRAL/TRIO domain Pkinase_Tyr PF07714.12 CEP07456.1 - 3.4e-27 95.1 0.0 6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CRAL_TRIO_2 PF13716.1 CEP07456.1 - 1.6e-09 37.8 0.5 1.8e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP07456.1 - 6.6e-06 26.1 0.0 2.4e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1326 PF07040.6 CEP07456.1 - 0.16 11.7 0.6 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) Polysacc_deac_1 PF01522.16 CEP07457.1 - 1.3e-28 99.0 0.0 2.5e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Cloacin_immun PF03513.9 CEP07457.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Cloacin immunity protein DUF4654 PF15547.1 CEP07458.1 - 0.48 10.7 6.4 0.056 13.7 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4654) TGT PF01702.13 CEP07459.1 - 1.4e-54 184.9 0.0 1.9e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Amidohydro_2 PF04909.9 CEP07460.1 - 5e-09 36.1 0.0 8.7e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CEP07460.1 - 9.9e-09 35.6 0.0 1.3e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase HEAT PF02985.17 CEP07461.1 - 0.00029 20.6 0.3 4 7.7 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat UBN2 PF14223.1 CEP07461.1 - 0.061 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ipi1_N PF12333.3 CEP07461.1 - 0.064 13.2 4.9 0.83 9.6 0.0 3.6 3 1 1 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation WD40 PF00400.27 CEP07462.1 - 5.8e-77 251.0 17.4 1.6e-08 34.1 0.1 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 CEP07462.1 - 1.6e-18 66.6 0.2 2.9e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CEP07462.1 - 0.0075 14.4 12.5 3.6 5.6 0.1 6.0 4 2 1 5 5 5 3 Nucleoporin Nup120/160 CHCH PF06747.8 CEP07463.1 - 4.2e-06 26.5 11.0 7.3e-06 25.7 7.6 1.4 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 CEP07463.1 - 0.0022 18.0 4.5 0.0033 17.5 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Pet191_N PF10203.4 CEP07463.1 - 0.047 13.7 5.9 0.066 13.2 4.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Hydrolase_2 PF07486.7 CEP07463.1 - 0.053 14.0 0.2 0.056 13.9 0.1 1.2 1 0 0 1 1 1 0 Cell Wall Hydrolase UPF0203 PF05254.7 CEP07463.1 - 0.78 9.6 10.2 0.46 10.3 3.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Ribosomal_60s PF00428.14 CEP07464.1 - 1.4e-24 86.3 6.1 2e-24 85.7 4.3 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1183 PF06682.7 CEP07465.1 - 0.003 17.2 0.0 0.003 17.2 0.0 2.4 1 1 1 2 2 1 1 Protein of unknown function (DUF1183) Podoplanin PF05808.6 CEP07465.1 - 0.018 14.6 5.1 0.03 13.8 3.6 1.4 1 0 0 1 1 1 0 Podoplanin DUF912 PF06024.7 CEP07465.1 - 0.04 13.9 0.6 0.33 11.0 0.4 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ESSS PF10183.4 CEP07465.1 - 0.082 13.3 0.1 0.26 11.7 0.1 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1201 PF06716.6 CEP07465.1 - 0.089 12.6 0.6 0.21 11.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Med3 PF11593.3 CEP07465.1 - 0.097 11.8 9.9 0.12 11.5 6.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TMEM154 PF15102.1 CEP07465.1 - 0.17 11.5 16.3 69 3.1 11.3 2.2 1 1 0 1 1 1 0 TMEM154 protein family UPF0233 PF06781.7 CEP07465.1 - 0.21 11.2 1.3 0.53 9.9 0.6 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) Ctr PF04145.10 CEP07465.1 - 0.33 10.9 2.5 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 Ctr copper transporter family HAMP PF00672.20 CEP07465.1 - 0.34 11.1 1.2 0.83 9.8 0.2 1.9 2 0 0 2 2 2 0 HAMP domain BPD_transp_2 PF02653.11 CEP07465.1 - 0.57 9.0 5.2 0.88 8.4 3.6 1.3 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF1180 PF06679.7 CEP07465.1 - 1.5 8.6 14.2 14 5.5 6.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) PAP1 PF08601.5 CEP07465.1 - 1.9 8.1 12.0 2.8 7.5 8.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Ashwin PF15323.1 CEP07465.1 - 2.3 8.1 12.4 3.4 7.6 8.6 1.2 1 0 0 1 1 1 0 Developmental protein Herpes_capsid PF06112.6 CEP07465.1 - 2.8 7.9 18.5 5.1 7.1 12.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein NDUF_C2 PF06374.6 CEP07466.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) GTP1_OBG PF01018.17 CEP07467.1 - 2.4e-43 147.4 7.0 1.7e-27 95.9 3.2 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CEP07467.1 - 2.1e-22 79.2 0.0 3.9e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP07467.1 - 9.3e-10 37.9 0.0 2.5e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 CEP07467.1 - 5.2e-08 32.3 0.0 8.5e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP07467.1 - 0.00038 19.6 0.0 0.00059 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP07467.1 - 0.0027 17.1 0.6 0.86 9.0 0.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CEP07467.1 - 0.0031 18.0 0.0 0.0082 16.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 CEP07467.1 - 0.0071 15.7 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CEP07467.1 - 0.0085 14.8 0.1 0.73 8.5 0.0 2.2 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 CEP07467.1 - 0.0094 15.7 0.1 3.1 7.5 0.0 2.5 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.22 CEP07467.1 - 0.019 15.2 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Ribosomal_L10 PF00466.15 CEP07468.1 - 6.6e-26 90.1 0.4 1.2e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CEP07468.1 - 3.4e-20 72.2 5.1 1.6e-19 70.1 2.8 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Fungal_trans PF04082.13 CEP07470.1 - 4.6e-34 117.4 0.6 9.5e-34 116.4 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPRY PF00622.23 CEP07471.1 - 1.8e-20 73.3 0.1 2.8e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 SPRY domain Endosulfine PF04667.12 CEP07472.1 - 1.6e-22 79.2 0.0 1.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region bZIP_2 PF07716.10 CEP07474.1 - 9.9e-12 44.5 6.5 9.9e-12 44.5 4.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP07474.1 - 1.3e-09 37.8 9.5 1.3e-09 37.8 6.6 2.2 2 1 1 3 3 2 2 bZIP transcription factor bZIP_Maf PF03131.12 CEP07474.1 - 1.9e-05 24.8 3.6 1.9e-05 24.8 2.5 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor IER PF05760.7 CEP07474.1 - 0.0058 16.6 0.4 0.0076 16.2 0.2 1.2 1 0 0 1 1 1 1 Immediate early response protein (IER) M PF02370.11 CEP07474.1 - 0.059 13.7 4.3 1 9.9 0.3 3.6 2 1 1 3 3 3 0 M protein repeat ASD2 PF08687.6 CEP07474.1 - 0.16 11.2 9.1 1.2 8.4 6.9 1.8 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 ADIP PF11559.3 CEP07474.1 - 0.25 11.2 12.1 0.031 14.1 4.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4094 PF13334.1 CEP07474.1 - 0.38 11.1 3.4 1 9.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) APG6 PF04111.7 CEP07474.1 - 1.5 7.8 9.7 1.9 7.4 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CEP07474.1 - 3.7 7.1 11.4 0.072 12.5 0.8 2.4 1 1 1 2 2 2 0 Septum formation initiator Striatin PF08232.7 CEP07474.1 - 4.1 7.7 11.3 0.21 11.9 1.1 2.2 1 1 1 2 2 2 0 Striatin family V_ATPase_I PF01496.14 CEP07474.1 - 5 4.8 5.8 6.7 4.4 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2681 PF10883.3 CEP07474.1 - 7.1 6.9 9.1 10 6.4 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Methyltransf_23 PF13489.1 CEP07475.1 - 1.8e-15 57.0 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP07475.1 - 6.6e-15 55.3 0.0 2e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP07475.1 - 1.1e-12 48.1 0.0 2.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP07475.1 - 6.2e-11 42.0 0.0 3.9e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP07475.1 - 2.1e-09 37.7 0.0 4.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP07475.1 - 2.2e-08 34.6 0.0 4.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP07475.1 - 2.1e-07 30.1 0.0 4.3e-06 25.9 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase CheR PF01739.13 CEP07475.1 - 1.2e-05 24.6 0.0 0.00017 20.9 0.0 2.4 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 CEP07475.1 - 6.6e-05 22.1 0.0 0.00058 19.0 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CEP07475.1 - 0.0002 21.3 0.0 0.00051 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 CEP07475.1 - 0.0014 17.0 0.0 0.016 13.6 0.0 2.1 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.7 CEP07475.1 - 0.0016 18.0 0.0 0.015 14.8 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF938) TehB PF03848.9 CEP07475.1 - 0.0071 15.5 0.1 0.052 12.7 0.1 2.1 1 1 0 1 1 1 1 Tellurite resistance protein TehB Pox_MCEL PF03291.11 CEP07475.1 - 0.0093 14.8 0.8 0.48 9.2 0.0 2.7 3 0 0 3 3 3 1 mRNA capping enzyme MTS PF05175.9 CEP07475.1 - 0.021 14.2 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 CEP07475.1 - 0.031 13.4 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 CEP07475.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 CEP07475.1 - 0.09 12.3 0.0 0.33 10.5 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.8 CEP07475.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 CEP07475.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) KAR9 PF08580.5 CEP07475.1 - 1.8 6.6 15.8 0.32 9.2 7.7 1.8 2 0 0 2 2 2 0 Yeast cortical protein KAR9 Macoilin PF09726.4 CEP07475.1 - 7 4.7 10.1 9.3 4.3 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein MobA_MobL PF03389.10 CEP07476.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 MobA/MobL family IF3_C PF00707.17 CEP07477.1 - 6.5e-16 57.8 1.2 1.4e-15 56.8 0.9 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 CEP07477.1 - 2.2e-09 37.1 0.0 4.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 CEP07477.1 - 0.0017 17.7 5.6 0.0031 16.8 3.9 1.5 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF3745 PF12560.3 CEP07477.1 - 6.6 6.4 6.1 0.69 9.6 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3745) Aminotran_1_2 PF00155.16 CEP07479.1 - 8.4e-64 215.7 0.0 9.7e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CEP07479.1 - 4.6e-07 29.1 0.0 7.7e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CEP07479.1 - 1.3e-05 23.6 0.0 3.2e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CEP07479.1 - 4.1e-05 22.8 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CEP07479.1 - 0.003 16.3 0.0 0.058 12.1 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V T_hemolysin PF12261.3 CEP07479.1 - 0.078 12.5 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Thermostable hemolysin LSM14 PF12701.2 CEP07481.1 - 8.3e-35 118.4 0.0 8.3e-35 118.4 0.0 3.1 3 1 0 3 3 3 1 Scd6-like Sm domain FDF PF09532.5 CEP07481.1 - 1.1e-15 58.0 14.1 1.1e-15 58.0 9.8 4.0 3 1 0 3 3 3 1 FDF domain SM-ATX PF14438.1 CEP07481.1 - 0.00014 21.7 0.0 0.00049 19.9 0.0 2.0 1 0 0 1 1 1 1 Ataxin 2 SM domain M-factor PF03855.8 CEP07483.1 - 0.058 13.3 1.3 6.9 6.7 0.0 2.8 3 1 0 3 3 3 0 M-factor Pkinase PF00069.20 CEP07484.1 - 7.4e-68 228.4 0.0 1.8e-67 227.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07484.1 - 9.8e-36 123.1 0.0 1.7e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP07484.1 - 2.9e-07 29.7 0.0 8.8e-07 28.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like KA1 PF02149.14 CEP07484.1 - 6.9e-05 22.2 0.0 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 CEP07484.1 - 0.00022 20.6 0.5 0.00047 19.5 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CEP07484.1 - 0.0013 17.8 1.1 0.0028 16.7 0.8 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP07484.1 - 0.039 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PBP1_TM PF14812.1 CEP07485.1 - 0.63 10.3 6.7 2.1 8.7 4.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 CEP07485.1 - 1.5 8.6 9.6 17 5.2 0.1 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 CEP07485.1 - 1.6 8.2 8.4 3.3 7.1 5.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CEP07485.1 - 7.3 5.7 10.2 11 5.1 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein AAA_25 PF13481.1 CEP07487.1 - 0.00078 18.8 0.1 0.31 10.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain IMPDH PF00478.20 CEP07487.1 - 0.08 11.8 0.5 0.17 10.7 0.2 1.5 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain NUDE_C PF04880.8 CEP07488.1 - 2.1e-09 37.9 19.5 3.2e-08 34.0 13.5 2.7 1 1 0 1 1 1 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.3 CEP07488.1 - 0.0005 17.5 23.8 0.00058 17.3 16.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Filament PF00038.16 CEP07488.1 - 0.00095 18.7 6.2 0.00095 18.7 4.3 3.2 1 1 2 3 3 3 1 Intermediate filament protein Fib_alpha PF08702.5 CEP07488.1 - 0.0069 16.5 12.6 0.0069 16.5 8.7 2.6 2 1 1 3 3 2 1 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 CEP07488.1 - 0.025 14.3 37.9 0.37 10.5 13.1 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 CEP07488.1 - 0.029 13.5 9.4 0.29 10.2 2.8 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3810 PF12725.2 CEP07488.1 - 0.19 10.6 10.1 0.39 9.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) MAD PF05557.8 CEP07488.1 - 0.24 9.4 35.6 0.38 8.7 24.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Frankia_peptide PF14407.1 CEP07488.1 - 0.25 11.1 8.3 0.48 10.2 1.0 3.1 2 1 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. GAS PF13851.1 CEP07488.1 - 0.31 10.1 38.4 0.85 8.7 13.7 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Allexi_40kDa PF05549.6 CEP07488.1 - 0.33 10.1 16.9 0.69 9.1 1.6 2.8 1 1 1 3 3 3 0 Allexivirus 40kDa protein DUF904 PF06005.7 CEP07488.1 - 2.9 8.2 39.9 0.095 13.0 9.6 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF904) TFR_dimer PF04253.10 CEP07488.1 - 3.2 7.3 8.5 9.8 5.7 3.3 3.3 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain APG6 PF04111.7 CEP07488.1 - 3.8 6.4 41.0 1.8 7.5 11.4 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Noelin-1 PF12308.3 CEP07488.1 - 4.4 7.1 14.6 0.21 11.4 4.3 2.9 2 1 2 4 4 4 0 Neurogenesis glycoprotein DUF730 PF05325.6 CEP07488.1 - 6.2 6.6 11.3 0.16 11.7 1.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF730) TMF_TATA_bd PF12325.3 CEP07488.1 - 6.9 6.4 38.2 5.9 6.6 8.2 4.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 CEP07488.1 - 7.4 6.4 42.6 1.3 8.8 7.9 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YjcZ PF13990.1 CEP07488.1 - 8.4 5.4 16.6 0.42 9.6 2.3 2.3 1 1 1 2 2 2 0 YjcZ-like protein AMP-binding PF00501.23 CEP07489.1 - 5.4e-81 272.1 0.0 6.5e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP07489.1 - 9.6e-17 61.7 0.2 2.6e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Iso_dh PF00180.15 CEP07490.1 - 9.7e-81 271.4 0.4 1.1e-80 271.1 0.3 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF914 PF06027.7 CEP07492.1 - 1.6e-100 336.2 14.8 2e-100 335.9 10.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CEP07492.1 - 8.2e-06 24.9 16.7 8.2e-06 24.9 11.5 1.6 1 1 0 2 2 2 1 UAA transporter family TPT PF03151.11 CEP07492.1 - 0.0002 21.0 23.9 0.0035 16.9 0.4 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 CEP07492.1 - 0.00033 20.7 29.6 0.0011 19.0 6.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family TBP PF00352.16 CEP07493.1 - 1.9e-70 232.2 0.1 6.6e-35 118.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CEP07493.1 - 0.00021 21.2 0.1 0.62 10.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) FAD-oxidase_C PF02913.14 CEP07494.1 - 9.2e-52 175.8 0.0 1.3e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CEP07494.1 - 4.9e-32 110.2 0.0 7.6e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PX PF00787.19 CEP07495.1 - 1.1e-18 67.0 0.3 2.5e-18 65.9 0.2 1.6 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 CEP07495.1 - 1.1e-07 31.4 1.2 3.5e-07 29.8 0.8 2.0 1 0 0 1 1 1 1 SNARE domain Polysacc_deac_1 PF01522.16 CEP07496.1 - 4.2e-25 87.7 0.0 8e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP07496.1 - 4.1e-05 22.6 0.0 7.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 RNA_pol_Rpb2_6 PF00562.23 CEP07497.1 - 5.6e-114 380.8 1.3 7.9e-114 380.3 0.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CEP07497.1 - 2.7e-29 101.5 0.0 4.1e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CEP07497.1 - 1.8e-23 82.0 0.0 4.3e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CEP07497.1 - 1.6e-22 79.8 0.0 2.8e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 CEP07497.1 - 1.5e-21 76.0 0.0 2.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 CEP07497.1 - 1.9e-20 72.8 0.0 3.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CEP07497.1 - 0.00087 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Sugar_tr PF00083.19 CEP07499.1 - 4.4e-119 398.0 25.6 1.3e-89 300.8 11.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP07499.1 - 1.9e-36 125.5 18.4 1.9e-36 125.5 12.8 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CEP07499.1 - 8.8e-07 27.5 9.1 1.2e-06 27.0 1.8 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CEP07499.1 - 3.1e-05 22.3 14.8 3.7e-05 22.0 2.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.1 CEP07499.1 - 0.00018 20.0 6.5 0.00018 20.0 4.5 3.4 2 1 0 3 3 3 2 MFS/sugar transport protein PSI PF01437.20 CEP07499.1 - 0.00086 19.4 4.4 0.0014 18.6 3.0 1.3 1 0 0 1 1 1 1 Plexin repeat Gp_dh_C PF02800.15 CEP07500.1 - 4e-74 247.2 0.0 5.7e-74 246.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CEP07500.1 - 3.8e-59 198.9 0.1 9.6e-59 197.6 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CEP07500.1 - 0.043 13.7 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus CTDII PF01556.13 CEP07501.1 - 5.8e-28 96.6 2.6 6.6e-20 70.8 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CEP07501.1 - 1.1e-26 92.3 3.9 1.8e-26 91.6 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CEP07501.1 - 5.9e-11 42.2 19.1 1e-10 41.4 13.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CEP07501.1 - 2.1 8.0 11.6 3.4 7.4 1.1 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 CEP07501.1 - 3.3 8.1 15.5 37 4.7 11.0 2.3 1 1 1 2 2 2 0 Cytochrome c3 BRO1 PF03097.13 CEP07503.1 - 1.1e-120 402.8 1.9 1.1e-120 402.8 1.3 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CEP07503.1 - 1.7e-56 191.4 15.1 1.7e-56 191.4 10.5 2.2 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV CorA PF01544.13 CEP07503.1 - 2.7 6.9 17.0 0.38 9.7 1.1 2.9 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Peptidase_C48 PF02902.14 CEP07504.1 - 4.4e-16 59.1 1.4 7.7e-16 58.3 1.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-C2H2_4 PF13894.1 CEP07506.1 - 3.2e-11 42.7 16.0 0.00091 19.3 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP07506.1 - 7e-11 41.8 19.9 0.00039 20.5 0.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP07506.1 - 1.8e-09 37.4 10.4 4.9e-05 23.4 0.0 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEP07506.1 - 0.0018 18.1 1.1 0.0018 18.1 0.8 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP07506.1 - 0.0043 17.1 14.1 0.76 10.0 1.8 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CEP07506.1 - 0.079 13.2 18.0 0.081 13.1 2.9 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-LYAR PF08790.6 CEP07506.1 - 0.55 9.9 5.9 2.6 7.8 0.1 3.0 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-met PF12874.2 CEP07506.1 - 1.1 9.6 6.5 14 6.0 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SHS2_Rpb7-N PF03876.12 CEP07507.1 - 1.6e-11 44.1 0.0 5e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 XkdW PF09636.5 CEP07509.1 - 0.0046 16.8 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 XkdW protein DDE_3 PF13358.1 CEP07510.1 - 5.1e-30 104.1 0.0 8.8e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP07510.1 - 0.00028 20.8 0.4 0.00081 19.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP07510.1 - 0.0003 21.5 0.0 0.00084 20.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 CEP07510.1 - 0.001 18.6 0.1 0.0033 17.0 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_psq PF05225.11 CEP07510.1 - 0.0021 17.5 0.0 0.0056 16.2 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 CEP07510.1 - 0.0022 17.2 0.2 0.02 14.0 0.1 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF1804 PF08822.6 CEP07510.1 - 0.0029 17.3 0.1 0.023 14.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1804) HTH_29 PF13551.1 CEP07510.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 CEP07510.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_7 PF02796.10 CEP07510.1 - 0.079 12.8 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Polysacc_deac_1 PF01522.16 CEP07511.1 - 1.9e-08 33.9 0.0 4.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase HTH_psq PF05225.11 CEP07512.1 - 1.4e-07 30.9 0.0 5.2e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP07512.1 - 1.4e-05 24.9 0.3 3.6e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.8 CEP07512.1 - 0.00014 21.2 0.0 0.00029 20.1 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 CEP07512.1 - 0.001 18.6 0.4 0.0051 16.4 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.17 CEP07512.1 - 0.027 14.3 0.1 0.12 12.2 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix FeoC PF09012.5 CEP07512.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Sigma70_r4 PF04545.11 CEP07512.1 - 0.048 12.9 0.2 0.13 11.5 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.1 CEP07512.1 - 0.048 13.7 0.2 0.19 11.9 0.1 2.0 1 1 1 2 2 2 0 Winged helix-turn helix HTH_37 PF13744.1 CEP07512.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PMM PF03332.8 CEP07514.1 - 4.7e-109 363.1 1.1 5.4e-109 362.9 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CEP07514.1 - 2.3e-06 27.3 0.0 1.6e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CEP07514.1 - 0.0031 16.8 0.0 2.1 7.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 CEP07514.1 - 0.06 13.5 0.1 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 CEP07514.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Motile_Sperm PF00635.21 CEP07515.1 - 2.9e-07 30.1 0.0 3.7e-06 26.5 0.0 2.6 2 1 0 2 2 2 1 MSP (Major sperm protein) domain eIF2A PF08662.6 CEP07516.1 - 1.5e-84 282.5 2.6 3.6e-80 268.2 0.0 3.5 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Pox_A_type_inc PF04508.7 CEP07516.1 - 2.4 8.1 4.4 5.2 7.1 3.0 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SURF4 PF02077.10 CEP07517.1 - 4.5e-59 200.0 4.9 3e-33 115.3 0.8 2.0 1 1 1 2 2 2 2 SURF4 family DUF2798 PF11391.3 CEP07517.1 - 0.52 10.1 7.5 0.4 10.4 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) DUF624 PF04854.9 CEP07517.1 - 0.6 10.0 7.8 0.12 12.2 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF624 PepSY_TM_2 PF13703.1 CEP07517.1 - 1.5 9.0 7.1 0.89 9.7 0.7 2.6 2 2 0 2 2 2 0 PepSY-associated TM helix DUF1212 PF06738.7 CEP07517.1 - 8.5 5.7 10.0 0.75 9.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Semialdhyde_dhC PF02774.13 CEP07518.1 - 4.6e-40 137.4 0.1 6.3e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CEP07518.1 - 1.9e-31 108.8 0.0 3.4e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 CEP07518.1 - 0.013 14.9 0.1 0.035 13.5 0.1 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 CEP07518.1 - 0.022 15.2 0.0 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ldh_1_N PF00056.18 CEP07518.1 - 0.04 13.7 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 CEP07518.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cyclin_N PF00134.18 CEP07519.1 - 2.3e-14 53.0 0.3 4.3e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Asp PF00026.18 CEP07520.1 - 1.6e-62 211.5 1.8 2.5e-62 210.9 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribosomal_S24e PF01282.14 CEP07520.1 - 6.2e-35 118.8 0.1 2e-34 117.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein S24e TAXi_N PF14543.1 CEP07520.1 - 1.1e-11 44.9 0.0 4.3e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP07520.1 - 1.1e-05 24.9 0.0 4.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CEP07520.1 - 0.00038 20.8 0.0 1.1 9.7 0.0 3.4 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 CEP07520.1 - 0.12 12.2 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sld5 PF05916.6 CEP07521.1 - 1.4e-09 38.2 0.0 2.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Acetyltransf_1 PF00583.19 CEP07522.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP07522.1 - 0.0025 17.9 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF106 PF01956.11 CEP07522.1 - 0.0038 16.7 0.7 0.018 14.5 0.1 2.1 2 0 0 2 2 2 1 Integral membrane protein DUF106 RhoGEF PF00621.15 CEP07523.1 - 2.9e-26 92.4 2.9 2.9e-26 92.4 2.0 1.8 2 0 0 2 2 2 1 RhoGEF domain MFS_1 PF07690.11 CEP07525.1 - 2e-38 132.0 60.0 1.3e-28 99.7 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP07525.1 - 8.6e-10 37.5 27.5 1.2e-09 37.1 10.5 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 CEP07525.1 - 3.2e-05 22.7 40.7 0.00014 20.5 13.2 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MRL1 PF13003.2 CEP07526.1 - 1.5 8.6 5.0 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L1 zf-CCCH PF00642.19 CEP07528.1 - 6e-09 35.3 2.0 1.7e-08 33.9 1.4 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CEP07528.1 - 8.9 6.4 7.5 0.61 10.1 0.5 2.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type ABC_tran PF00005.22 CEP07529.1 - 8.3e-37 126.5 0.1 1.7e-35 122.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CEP07529.1 - 8.4e-27 94.2 10.3 1.9e-26 93.0 7.1 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CEP07529.1 - 8.9e-07 29.1 0.8 0.018 15.0 0.1 3.1 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 CEP07529.1 - 1.6e-06 27.5 6.1 4.6e-06 26.0 0.0 3.0 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CEP07529.1 - 0.0026 17.2 0.1 0.0079 15.6 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP07529.1 - 0.0032 17.4 0.0 0.0085 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CEP07529.1 - 0.005 16.7 0.1 0.075 12.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CEP07529.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP07529.1 - 0.01 15.9 0.0 0.091 12.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain UPF0121 PF03661.8 CEP07529.1 - 0.012 14.8 0.8 0.023 13.9 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) AAA_17 PF13207.1 CEP07529.1 - 0.02 15.7 0.0 0.049 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ARA70 PF12489.3 CEP07529.1 - 0.037 13.9 3.5 0.068 13.1 2.4 1.4 1 0 0 1 1 1 0 Nuclear coactivator SbcCD_C PF13558.1 CEP07529.1 - 0.11 12.4 0.2 1.4 8.9 0.1 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Thaumatin PF00314.12 CEP07530.1 - 3.4e-45 154.1 15.1 5.9e-44 150.0 10.4 2.0 1 1 0 1 1 1 1 Thaumatin family Zn_clus PF00172.13 CEP07531.1 - 0.00017 21.3 5.1 0.00035 20.3 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF883 PF05957.8 CEP07531.1 - 0.026 14.9 1.6 4.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) F-box PF00646.28 CEP07532.1 - 0.00057 19.4 0.0 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ferritin-like PF12902.2 CEP07533.1 - 0.041 13.4 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like DUF3437 PF11919.3 CEP07535.1 - 0.065 12.9 0.0 0.37 10.5 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) PAGK PF15284.1 CEP07536.1 - 0.11 12.2 0.2 0.16 11.7 0.1 1.4 1 1 0 1 1 1 0 Phage-encoded virulence factor zf-RVT PF13966.1 CEP07537.1 - 0.0021 18.3 1.1 0.0039 17.4 0.7 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase G-alpha PF00503.15 CEP07538.1 - 1.8e-66 224.4 4.4 2e-66 224.3 3.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP07538.1 - 8.9e-10 38.0 0.5 4e-09 35.9 0.1 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family zf-CHC2 PF01807.15 CEP07538.1 - 0.085 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger Nucleotid_trans PF03407.11 CEP07539.1 - 7.4e-26 91.2 0.2 1.1e-25 90.7 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Chs3p PF12271.3 CEP07540.1 - 3.8e-112 374.0 21.4 5.6e-112 373.4 14.8 1.2 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit TIM21 PF08294.6 CEP07540.1 - 1.5e-41 141.4 0.2 1.5e-41 141.4 0.2 2.0 2 0 0 2 2 2 1 TIM21 ArfGap PF01412.13 CEP07540.1 - 2.8e-29 101.2 0.1 2.8e-29 101.2 0.1 2.3 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Coa1 PF08695.5 CEP07540.1 - 3.3e-09 36.2 0.1 3.9e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Septin PF00735.13 CEP07541.1 - 2.9e-124 413.6 0.3 2.9e-124 413.6 0.2 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CEP07541.1 - 2e-08 34.2 0.0 3.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP07541.1 - 1.5e-06 27.4 0.0 3.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CEP07541.1 - 6.3e-06 25.7 1.1 0.00037 19.9 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CEP07541.1 - 0.00014 22.1 2.9 0.0016 18.7 0.1 2.5 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 CEP07541.1 - 0.00021 21.1 4.2 0.031 14.0 0.1 3.1 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 CEP07541.1 - 0.00043 19.4 0.0 0.00043 19.4 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 CEP07541.1 - 0.00079 19.9 0.6 0.0038 17.7 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein AAA_22 PF13401.1 CEP07541.1 - 0.00087 19.4 0.0 0.004 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ras PF00071.17 CEP07541.1 - 0.00096 18.5 1.1 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.7 CEP07541.1 - 0.0013 17.8 0.0 0.0035 16.5 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 CEP07541.1 - 0.0016 17.9 0.1 0.0041 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 CEP07541.1 - 0.0031 17.5 0.3 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CEP07541.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Exonuc_VII_L PF02601.10 CEP07541.1 - 0.08 12.1 6.3 0.2 10.8 4.3 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit PduV-EutP PF10662.4 CEP07541.1 - 0.085 12.3 0.1 1.8 8.0 0.0 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 CEP07541.1 - 0.087 12.2 2.4 0.16 11.3 0.0 2.4 2 1 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 CEP07541.1 - 0.29 10.8 2.6 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 CEP07541.1 - 1.1 8.7 4.1 15 5.0 0.0 3.2 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein IncA PF04156.9 CEP07541.1 - 3.7 7.1 7.3 7 6.1 5.0 1.5 1 0 0 1 1 1 0 IncA protein DSS1_SEM1 PF05160.8 CEP07542.1 - 0.00095 18.9 2.5 0.002 17.8 1.8 1.6 1 0 0 1 1 1 1 DSS1/SEM1 family Reo_sigmaC PF04582.7 CEP07542.1 - 0.17 11.0 3.1 0.27 10.3 2.2 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 CEP07542.1 - 0.74 9.6 5.1 0.35 10.6 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PseudoU_synth_1 PF01416.15 CEP07543.1 - 1.7e-32 111.9 0.0 1e-17 64.4 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase CobT PF06213.7 CEP07544.1 - 0.051 12.7 19.9 0.061 12.4 13.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-T PF15511.1 CEP07544.1 - 0.066 12.4 15.5 0.071 12.3 10.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pox_P4B PF03292.9 CEP07544.1 - 0.1 10.5 0.2 0.12 10.2 0.2 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Herpes_LMP1 PF05297.6 CEP07544.1 - 0.11 11.4 5.2 0.11 11.4 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Paf1 PF03985.8 CEP07544.1 - 0.14 10.8 22.1 0.17 10.5 15.3 1.1 1 0 0 1 1 1 0 Paf1 Merozoite_SPAM PF07133.6 CEP07544.1 - 0.16 11.8 30.0 0.24 11.2 20.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Zip PF02535.17 CEP07544.1 - 0.28 10.1 3.7 0.36 9.7 2.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BSMAP PF12280.3 CEP07544.1 - 0.32 10.8 2.9 0.37 10.6 2.0 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF2457 PF10446.4 CEP07544.1 - 0.59 8.8 19.2 0.88 8.2 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 CEP07544.1 - 0.79 9.0 22.8 1 8.6 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 CEP07544.1 - 0.92 9.3 30.5 0.046 13.5 17.4 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 CEP07544.1 - 1.7 7.0 27.0 1.9 6.8 18.7 1.1 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 CEP07544.1 - 2.7 7.7 9.0 3.6 7.3 6.2 1.3 1 0 0 1 1 1 0 DDHD domain Astro_capsid PF03115.9 CEP07544.1 - 3.8 5.6 7.6 4.2 5.4 5.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF3306 PF11748.3 CEP07544.1 - 3.8 8.2 16.3 5.9 7.5 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) RR_TM4-6 PF06459.7 CEP07544.1 - 4.6 7.0 15.4 5.1 6.8 10.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop25 PF09805.4 CEP07544.1 - 6.9 6.7 20.5 9.6 6.2 14.2 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CENP-T PF15511.1 CEP07546.1 - 0.0046 16.2 20.4 0.0054 16.0 14.2 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T BUD22 PF09073.5 CEP07546.1 - 0.04 13.0 25.7 0.045 12.8 17.8 1.1 1 0 0 1 1 1 0 BUD22 Zip PF02535.17 CEP07546.1 - 0.097 11.6 5.1 0.1 11.5 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Daxx PF03344.10 CEP07546.1 - 0.67 8.3 35.5 1.1 7.7 24.6 1.3 1 0 0 1 1 1 0 Daxx Family PLRV_ORF5 PF01690.12 CEP07546.1 - 1.2 8.1 14.1 1.5 7.8 9.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RR_TM4-6 PF06459.7 CEP07546.1 - 4.8 6.9 16.2 7.7 6.3 11.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.7 CEP07546.1 - 6.5 5.9 40.8 8.1 5.6 28.3 1.1 1 0 0 1 1 1 0 SDA1 MIP-T3 PF10243.4 CEP07546.1 - 8.2 4.7 25.0 10 4.4 17.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Toxin-JAB1 PF15659.1 CEP07547.1 - 0.88 9.4 7.2 0.088 12.6 1.8 1.7 2 0 0 2 2 2 0 JAB-like toxin 1 ABC2_membrane PF01061.19 CEP07548.1 - 1.2e-86 289.1 64.4 3e-47 160.4 14.1 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CEP07548.1 - 1.9e-35 122.1 0.1 2.5e-18 66.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 CEP07548.1 - 6.7e-25 86.7 2.4 2.6e-16 59.1 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 CEP07548.1 - 1.4e-14 53.9 36.3 1.3e-08 34.2 8.2 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 CEP07548.1 - 6.2e-11 42.2 0.0 1.9e-10 40.7 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 CEP07548.1 - 1.8e-05 23.9 0.0 0.0023 17.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CEP07548.1 - 2.4e-05 23.8 0.0 0.0039 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CEP07548.1 - 9.9e-05 22.4 1.7 0.2 11.6 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.1 CEP07548.1 - 0.00017 21.0 0.8 0.0081 15.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CEP07548.1 - 0.001 19.2 0.1 0.2 11.7 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CEP07548.1 - 0.0014 18.6 1.4 0.28 11.1 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CEP07548.1 - 0.0036 17.0 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain cobW PF02492.14 CEP07548.1 - 0.0043 16.5 1.1 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 CEP07548.1 - 0.0054 16.3 1.7 1.4 8.5 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CEP07548.1 - 0.011 16.0 0.0 0.76 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CEP07548.1 - 0.033 13.6 1.4 2.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CEP07548.1 - 0.045 13.4 1.2 2.5 7.7 0.1 3.0 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.17 CEP07548.1 - 0.092 11.5 0.3 2.5 6.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 CEP07548.1 - 0.1 12.5 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CEP07548.1 - 0.2 10.7 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 CEP07548.1 - 0.2 11.6 1.9 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CEP07548.1 - 0.21 12.4 0.0 1 10.1 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 CEP07548.1 - 0.22 11.4 0.1 0.92 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CEP07548.1 - 0.46 10.7 1.5 0.65 10.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 CEP07548.1 - 0.47 10.0 0.5 8.1 5.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Aldedh PF00171.17 CEP07549.1 - 3e-134 447.8 0.0 3.8e-134 447.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M20 PF01546.23 CEP07549.1 - 3e-07 30.1 0.3 5.5e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_C3 PF00548.15 CEP07549.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) M20_dimer PF07687.9 CEP07549.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Peptidase dimerisation domain FAT PF02259.18 CEP07551.1 - 9.2e-74 248.5 9.9 9.2e-74 248.5 6.9 2.6 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 CEP07551.1 - 2.7e-22 79.4 1.7 1.3e-21 77.2 1.2 2.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CEP07551.1 - 2.7e-06 26.6 0.7 7e-06 25.3 0.5 1.7 1 0 0 1 1 1 1 FATC domain CDK5_activator PF03261.10 CEP07551.1 - 1.1 8.5 14.6 1 8.6 8.7 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein F-box-like PF12937.2 CEP07552.1 - 6.7e-08 32.1 0.1 2.2e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP07552.1 - 0.0015 18.1 0.1 0.0058 16.2 0.1 2.0 1 0 0 1 1 1 1 F-box domain DUF226 PF02890.9 CEP07552.1 - 0.021 14.5 0.6 0.021 14.5 0.4 2.2 2 1 0 2 2 2 0 Borrelia family of unknown function DUF226 Pentapeptide_4 PF13599.1 CEP07552.1 - 0.029 14.1 0.4 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) VPS11_C PF12451.3 CEP07552.1 - 0.11 12.4 0.3 0.44 10.4 0.1 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Vac7 PF12751.2 CEP07553.1 - 0.19 10.5 0.1 0.32 9.8 0.1 1.4 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 SHP PF03579.8 CEP07553.1 - 0.2 11.0 1.4 0.36 10.2 1.0 1.3 1 0 0 1 1 1 0 Small hydrophobic protein DUF997 PF06196.7 CEP07553.1 - 0.93 9.0 4.2 1.7 8.1 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) F-box-like PF12937.2 CEP07554.1 - 4.3e-05 23.1 0.7 0.00012 21.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like Svf1 PF08622.5 CEP07555.1 - 3.4e-82 276.0 6.8 4e-82 275.7 4.7 1.1 1 0 0 1 1 1 1 Svf1-like UPF0020 PF01170.13 CEP07556.1 - 5.1e-14 52.2 0.0 9.9e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CEP07556.1 - 2.1e-08 34.1 0.0 3.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 CEP07556.1 - 0.00027 20.1 0.0 0.00047 19.3 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 CEP07556.1 - 0.0027 17.2 0.0 0.95 8.9 0.0 2.6 2 1 1 3 3 3 2 DNA methylase DUF4477 PF14780.1 CEP07557.1 - 2.8e-20 72.4 3.2 4.1e-20 71.9 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) F-box-like PF12937.2 CEP07558.1 - 4.4e-09 35.9 0.4 1.4e-08 34.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP07558.1 - 0.013 15.1 1.3 0.013 15.1 0.9 2.5 2 1 0 2 2 2 0 F-box domain LRR_8 PF13855.1 CEP07558.1 - 0.037 13.7 1.1 0.59 9.9 0.1 3.2 3 0 0 3 3 3 0 Leucine rich repeat SDH_alpha PF03313.10 CEP07559.1 - 6.9e-102 340.2 0.1 1e-101 339.7 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 CEP07559.1 - 2.3e-56 190.1 0.0 4.4e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain MmgE_PrpD PF03972.9 CEP07559.1 - 0.047 11.8 0.6 0.072 11.2 0.4 1.2 1 0 0 1 1 1 0 MmgE/PrpD family SPX PF03105.14 CEP07559.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 SPX domain HIT PF01230.18 CEP07560.1 - 2.3e-13 50.4 0.0 2.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CEP07560.1 - 1.1e-06 28.8 0.0 1.2e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CEP07560.1 - 0.00082 19.0 0.1 0.00095 18.8 0.1 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 E1-E2_ATPase PF00122.15 CEP07561.1 - 1.9e-61 207.0 1.9 4.2e-61 205.9 1.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEP07561.1 - 6e-29 102.0 0.0 1.9e-28 100.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP07561.1 - 8.6e-21 73.7 0.0 2.2e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_C PF00689.16 CEP07561.1 - 1.8e-19 69.9 14.7 1.5e-14 53.9 1.9 2.9 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus HAD PF12710.2 CEP07561.1 - 1.5e-14 54.6 0.0 2.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP07561.1 - 1.1e-08 34.3 0.0 2.5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP07561.1 - 8.5e-05 22.2 0.8 0.036 13.6 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Nop16 PF09420.5 CEP07562.1 - 0.0039 17.2 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 zf-CCHC PF00098.18 CEP07564.1 - 7.6e-05 22.4 1.8 0.00013 21.7 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CEP07564.1 - 0.0008 19.0 0.2 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DDE_3 PF13358.1 CEP07565.1 - 0.039 13.6 0.3 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease AAA_assoc PF14363.1 CEP07565.1 - 0.05 13.6 1.6 0.33 11.0 0.3 2.5 1 1 1 2 2 2 0 Domain associated at C-terminal with AAA IncA PF04156.9 CEP07565.1 - 0.99 8.9 4.9 3.6 7.1 3.5 1.8 1 1 1 2 2 2 0 IncA protein CTP_transf_2 PF01467.21 CEP07566.1 - 1.1e-22 80.7 0.0 3.5e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase UQ_con PF00179.21 CEP07567.1 - 1.8e-14 53.3 0.0 2.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rubredoxin PF00301.15 CEP07567.1 - 0.27 11.1 1.5 0.41 10.5 0.1 2.0 2 0 0 2 2 2 0 Rubredoxin ACOX PF01756.14 CEP07569.1 - 4.7e-44 149.9 0.3 9.9e-44 148.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEP07569.1 - 1.3e-29 102.9 0.3 2.5e-29 102.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEP07569.1 - 1.2e-12 47.1 1.2 3.5e-12 45.6 0.1 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEP07569.1 - 0.00028 20.9 0.8 0.00088 19.3 0.0 2.3 4 0 0 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEP07569.1 - 0.011 16.3 0.0 0.042 14.4 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain PXA PF02194.10 CEP07570.1 - 6e-44 149.8 0.3 6e-44 149.8 0.2 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 CEP07570.1 - 2e-25 89.0 0.3 2e-25 89.0 0.2 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CEP07570.1 - 3.2e-20 72.0 0.0 1.7e-19 69.6 0.0 2.3 1 0 0 1 1 1 1 PX domain RGS PF00615.14 CEP07570.1 - 3.7e-14 52.8 5.3 5.8e-13 48.9 3.0 3.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_Tyr PF07714.12 CEP07572.1 - 1.2e-22 80.1 0.0 1.6e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CEP07572.1 - 1.6e-21 76.6 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PEX-1N PF09262.6 CEP07572.1 - 0.085 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Peptidase_C14 PF00656.17 CEP07573.1 - 6e-61 206.2 0.0 8.1e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Ank_2 PF12796.2 CEP07574.1 - 1e-24 86.6 1.9 1.5e-12 47.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEP07574.1 - 3.1e-18 64.5 5.6 5.7e-06 25.8 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CEP07574.1 - 2.5e-16 59.3 1.0 9.6e-08 32.0 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP07574.1 - 1.3e-15 55.9 0.6 0.00012 21.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CEP07574.1 - 8.1e-14 51.6 0.2 1.9e-05 24.9 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF4407 PF14362.1 CEP07574.1 - 1.1 8.1 4.6 4.7 6.0 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Myosin_head PF00063.16 CEP07575.1 - 1.6e-16 59.5 0.1 1.8e-16 59.3 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) SNF2_N PF00176.18 CEP07576.1 - 5.6e-57 192.7 2.0 8.4e-57 192.2 0.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP07576.1 - 1.8e-13 50.1 0.0 8.9e-13 47.9 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 CEP07576.1 - 4.4e-07 29.4 3.0 4.9e-07 29.3 0.2 2.7 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain C1_1 PF00130.17 CEP07576.1 - 5.6e-06 26.0 16.2 0.00037 20.1 3.0 3.3 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CEP07576.1 - 1.7e-05 24.4 13.9 0.00011 21.7 1.1 2.5 2 0 0 2 2 2 2 PHD-finger Chromo_shadow PF01393.14 CEP07576.1 - 0.00051 19.8 1.6 0.028 14.2 0.0 3.1 3 0 0 3 3 3 1 Chromo shadow domain PHD_2 PF13831.1 CEP07576.1 - 6.2 6.2 20.8 0.064 12.5 2.3 2.8 3 0 0 3 3 3 0 PHD-finger NTP_transferase PF00483.18 CEP07577.1 - 4e-47 160.6 0.0 5.5e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CEP07577.1 - 6e-11 41.3 10.9 2e-09 36.5 2.3 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CEP07577.1 - 6.2e-10 39.3 0.0 8.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CEP07577.1 - 2.2e-05 23.9 4.7 2.2e-05 23.9 3.2 3.1 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CEP07577.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF2810 PF10928.3 CEP07577.1 - 0.1 12.3 0.1 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2810) Lectin_legB PF00139.14 CEP07579.1 - 3.5e-16 59.2 0.0 8.7e-16 58.0 0.0 1.6 1 1 0 1 1 1 1 Legume lectin domain Transglut_core PF01841.14 CEP07579.1 - 6.9e-13 48.7 0.2 1.7e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 CEP07579.1 - 5.2e-12 45.3 1.5 1e-11 44.4 1.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Lectin_leg-like PF03388.8 CEP07579.1 - 6.1e-07 28.8 0.0 0.018 14.1 0.0 2.4 2 0 0 2 2 2 2 Legume-like lectin family zf-RVT PF13966.1 CEP07581.1 - 0.0051 17.1 0.9 0.012 15.9 0.6 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 CEP07583.1 - 1.9e-18 66.6 0.0 3.6e-18 65.6 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_1d PF00750.14 CEP07584.1 - 4.8e-74 249.2 0.8 5.8e-74 249.0 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CEP07584.1 - 8e-24 83.8 0.1 1.7e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CEP07584.1 - 0.066 13.7 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Surp PF01805.15 CEP07585.1 - 2.6e-17 62.2 0.0 8.3e-17 60.5 0.0 2.0 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 CEP07585.1 - 1.4e-15 56.6 0.0 2.6e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07585.1 - 1.6e-12 47.1 0.0 3.4e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07585.1 - 3.9e-07 29.8 0.0 7.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 CEP07585.1 - 6.4e-05 23.1 0.9 0.00019 21.5 0.6 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Asn_synthase PF00733.16 CEP07586.1 - 7.3e-53 179.6 0.0 1.3e-52 178.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CEP07586.1 - 3.2e-06 26.8 0.0 1.2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CEP07586.1 - 0.091 11.9 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein NUDIX PF00293.23 CEP07587.1 - 2.1e-11 43.5 0.0 2.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nucleopor_Nup85 PF07575.8 CEP07589.1 - 1.5e-28 99.3 8.8 7.1e-28 97.1 6.1 1.9 1 1 0 1 1 1 1 Nup85 Nucleoporin Dynactin PF12455.3 CEP07590.1 - 1.7e-68 230.5 12.0 1.7e-68 230.5 8.3 3.8 3 1 2 5 5 5 1 Dynein associated protein RRM_5 PF13893.1 CEP07592.1 - 5.8e-10 38.8 0.1 1.7e-09 37.4 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP07592.1 - 8.3e-07 28.5 0.1 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07592.1 - 6.4e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.6 CEP07592.1 - 0.00068 19.5 21.1 0.00068 19.5 14.6 1.9 2 0 0 2 2 2 1 Fruit fly transformer protein DUF1777 PF08648.7 CEP07592.1 - 0.0069 16.1 25.9 0.0069 16.1 18.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) RBM39linker PF15519.1 CEP07592.1 - 0.018 15.3 0.2 0.018 15.3 0.1 2.2 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF1840 PF08895.6 CEP07592.1 - 1.3 9.0 5.3 0.2 11.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PI3_PI4_kinase PF00454.22 CEP07593.1 - 9.7e-38 129.9 0.0 3.4e-37 128.1 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CEP07593.1 - 2e-22 79.2 0.0 5.3e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HTH_32 PF13565.1 CEP07597.1 - 2.5e-07 31.3 0.1 6.6e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP07597.1 - 3.6e-07 30.3 0.0 1.1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CEP07597.1 - 4.3e-05 23.4 3.0 0.0016 18.3 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP07597.1 - 0.001 18.6 2.3 0.038 13.6 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain Receptor_2B4 PF11465.3 CEP07597.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 HTH_17 PF12728.2 CEP07597.1 - 0.13 12.5 2.3 4.8 7.5 0.0 3.0 3 1 0 3 3 3 0 Helix-turn-helix domain Aminotran_3 PF00202.16 CEP07598.1 - 7.1e-108 360.4 0.0 8.4e-108 360.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DNA_mis_repair PF01119.14 CEP07599.1 - 1.5e-32 111.5 0.0 2.7e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CEP07599.1 - 2.9e-12 46.4 0.0 6.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CEP07599.1 - 4e-10 39.3 0.1 1.2e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 CEP07599.1 - 0.1 12.2 0.2 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 MutL C terminal dimerisation domain IncA PF04156.9 CEP07600.1 - 0.063 12.8 1.3 0.13 11.8 0.9 1.6 1 0 0 1 1 1 0 IncA protein COG5 PF10392.4 CEP07600.1 - 0.069 13.1 3.7 0.1 12.5 0.3 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 ADIP PF11559.3 CEP07600.1 - 0.67 9.8 5.2 0.15 11.9 0.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CorA PF01544.13 CEP07601.1 - 3e-47 161.0 0.1 4.5e-47 160.4 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EF-hand_1 PF00036.27 CEP07602.1 - 1.2e-36 121.1 16.0 4.8e-10 38.0 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEP07602.1 - 1.7e-34 117.7 6.0 4.7e-19 68.2 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP07602.1 - 1.1e-28 96.4 7.6 1.3e-08 33.9 0.1 4.4 3 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CEP07602.1 - 1.6e-28 98.0 15.9 2.3e-17 62.3 1.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CEP07602.1 - 4.9e-27 92.0 15.1 8.4e-08 31.2 0.2 4.5 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CEP07602.1 - 2.6e-13 49.6 0.0 9.7e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CEP07602.1 - 1.4e-09 37.6 3.1 0.00074 19.2 0.0 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CEP07602.1 - 1.5e-08 34.6 0.1 0.0001 22.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 CEP07602.1 - 0.00063 19.4 0.1 0.062 13.0 0.0 2.4 1 1 2 3 3 3 1 Tellurite resistance protein TerB UPF0154 PF03672.8 CEP07602.1 - 0.0047 16.5 0.0 0.61 9.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 CEP07602.1 - 0.037 13.5 0.2 0.095 12.2 0.1 1.8 1 1 0 1 1 1 0 Caleosin related protein SpoVIF PF14069.1 CEP07602.1 - 0.092 12.4 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Stage VI sporulation protein F DUF21 PF01595.15 CEP07602.1 - 0.14 11.4 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 Ribosomal_S3Ae PF01015.13 CEP07603.1 - 4.2e-63 212.2 5.2 4.8e-63 212.0 3.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF3571 PF12095.3 CEP07603.1 - 0.086 13.0 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) DUF496 PF04363.7 CEP07603.1 - 1 9.2 4.9 12 5.8 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF496) F-box-like PF12937.2 CEP07604.1 - 7.8e-11 41.5 0.2 1.7e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP07604.1 - 2.5e-07 30.1 0.0 5.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain SelP_N PF04592.9 CEP07604.1 - 0.011 15.1 1.4 0.017 14.5 1.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Elf1 PF05129.8 CEP07605.1 - 0.041 13.5 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like IQ PF00612.22 CEP07606.1 - 1.1e-05 24.6 0.6 2.5e-05 23.4 0.4 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Lzipper-MIP1 PF14389.1 CEP07606.1 - 0.0022 18.0 3.1 0.0022 18.0 2.2 3.5 1 1 3 4 4 4 1 Leucine-zipper of ternary complex factor MIP1 Myosin_tail_1 PF01576.14 CEP07606.1 - 0.0044 14.8 25.4 0.018 12.8 17.6 1.7 1 1 1 2 2 2 2 Myosin tail Glycos_transf_2 PF00535.21 CEP07606.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Occludin_ELL PF07303.8 CEP07606.1 - 1.9 9.2 15.9 0.17 12.5 5.2 3.2 2 1 2 4 4 4 0 Occludin homology domain SPT16 PF08644.6 CEP07606.1 - 5.6 6.8 9.0 4.6 7.0 4.4 2.2 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF4446 PF14584.1 CEP07606.1 - 8.4 6.2 12.9 0.33 10.7 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) MFS_1 PF07690.11 CEP07608.1 - 5.9e-24 84.4 41.5 5.9e-24 84.4 28.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP07609.1 - 3.4e-101 339.0 29.7 3.7e-51 174.1 2.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP07609.1 - 5.9e-29 100.8 16.1 5.9e-29 100.8 11.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 CEP07610.1 - 6.1e-20 70.6 0.1 9.7e-15 53.9 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07610.1 - 1.4e-08 34.6 0.0 4.7e-07 29.6 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07610.1 - 2.1e-05 24.2 0.0 0.0087 15.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FLO_LFY PF01698.11 CEP07610.1 - 0.2 10.4 12.5 0.29 9.9 8.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4045 PF13254.1 CEP07610.1 - 0.49 9.6 19.3 0.049 12.9 6.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 CEP07610.1 - 0.66 9.8 10.0 1.2 8.9 7.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region G-7-MTase PF12803.2 CEP07610.1 - 0.7 8.9 8.9 1.2 8.1 6.2 1.4 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) LMBR1 PF04791.11 CEP07610.1 - 2.1 6.8 3.7 2.6 6.5 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YjgP_YjgQ PF03739.9 CEP07610.1 - 3.2 6.3 11.9 5.1 5.7 8.3 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family AUX_IAA PF02309.11 CEP07610.1 - 3.3 7.4 14.3 1.3 8.7 8.1 1.8 2 0 0 2 2 2 0 AUX/IAA family FAM60A PF15396.1 CEP07610.1 - 3.4 7.3 17.2 8.3 6.0 11.9 1.6 1 0 0 1 1 1 0 Protein Family FAM60A MRI PF15325.1 CEP07610.1 - 8.9 7.3 8.7 4.8 8.2 3.7 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection Ank_4 PF13637.1 CEP07611.1 - 1.4e-20 73.2 1.8 4.1e-10 39.9 0.0 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEP07611.1 - 1.8e-17 63.4 1.5 5.9e-09 36.1 0.1 4.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEP07611.1 - 1.8e-12 46.3 6.7 0.0035 17.0 0.0 6.5 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 CEP07611.1 - 6.7e-12 45.2 1.9 7.9e-07 29.1 0.0 5.2 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP07611.1 - 5.4e-09 35.4 2.0 0.0019 18.2 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat DUF2097 PF09870.4 CEP07612.1 - 0.058 13.4 0.3 0.076 13.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) Phage_Integr_2 PF13009.1 CEP07612.1 - 0.11 11.4 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Putative phage integrase Cytochrom_C_2 PF01322.15 CEP07613.1 - 0.0068 16.9 2.3 0.02 15.4 1.6 1.8 1 0 0 1 1 1 1 Cytochrome C' WD40 PF00400.27 CEP07614.1 - 2.7e-26 90.4 12.8 8.8e-07 28.5 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CEP07614.1 - 4.1e-06 25.2 0.1 0.00068 17.9 0.0 2.6 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CEP07614.1 - 0.018 13.8 3.1 0.35 9.5 0.1 3.4 2 2 0 2 2 2 0 Nup133 N terminal like Nucleoplasmin PF03066.10 CEP07614.1 - 0.24 10.8 11.6 0.53 9.7 8.0 1.6 1 0 0 1 1 1 0 Nucleoplasmin Mit_ribos_Mrp51 PF11709.3 CEP07614.1 - 0.3 10.2 3.0 0.46 9.6 2.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit RXT2_N PF08595.6 CEP07614.1 - 0.32 10.7 9.7 0.6 9.9 6.3 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF2457 PF10446.4 CEP07614.1 - 0.37 9.4 14.8 0.55 8.8 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 CEP07614.1 - 7.1 5.7 8.6 10 5.2 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein SAM_decarbox PF01536.11 CEP07615.1 - 1.4e-98 329.5 1.8 2.1e-54 184.4 0.0 3.0 2 1 1 3 3 3 3 Adenosylmethionine decarboxylase Glyco_transf_49 PF13896.1 CEP07616.1 - 2.8e-35 121.9 8.4 7.4e-29 100.8 0.8 2.9 3 1 1 4 4 4 2 Glycosyl-transferase for dystroglycan DUF3336 PF11815.3 CEP07616.1 - 1.9e-27 95.5 3.0 5.9e-27 93.9 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CEP07616.1 - 1.2e-18 67.8 0.0 2.9e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Glyco_tranf_2_2 PF10111.4 CEP07616.1 - 0.00062 18.9 0.1 0.0016 17.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HLH PF00010.21 CEP07617.1 - 8e-18 63.8 0.5 2.2e-17 62.4 0.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Creb_binding PF09030.5 CEP07617.1 - 0.016 15.3 4.6 0.016 15.3 3.2 3.2 1 1 2 3 3 3 0 Creb binding FAM176 PF14851.1 CEP07617.1 - 4.7 6.8 8.2 2.5 7.7 3.6 1.9 1 1 1 2 2 2 0 FAM176 family zf-CCHC PF00098.18 CEP07619.1 - 0.0024 17.7 1.2 0.0024 17.7 0.8 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CEP07619.1 - 0.28 10.8 5.4 0.6 9.8 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF1357 PF07094.6 CEP07620.1 - 0.019 14.4 0.1 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) GAGA PF09237.6 CEP07621.1 - 0.0099 15.4 1.3 0.016 14.7 0.9 1.3 1 0 0 1 1 1 1 GAGA factor Chromo PF00385.19 CEP07623.1 - 5.6e-11 41.9 0.8 1e-10 41.1 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 CEP07623.1 - 0.0016 18.2 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Het-C PF07217.6 CEP07623.1 - 0.04 12.1 1.5 0.044 11.9 1.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Tudor-knot PF11717.3 CEP07623.1 - 0.21 11.3 4.6 0.48 10.1 0.3 2.2 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain DDE_3 PF13358.1 CEP07624.1 - 0.0005 19.8 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_CI_repr PF07022.8 CEP07625.1 - 0.0053 16.8 1.0 0.028 14.4 0.2 2.3 1 1 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain Phage_integrase PF00589.17 CEP07625.1 - 0.023 14.3 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family DDE_Tnp_1_7 PF13843.1 CEP07628.1 - 5.5e-45 153.9 0.0 6.2e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Glycohydro_20b2 PF14845.1 CEP07629.1 - 0.11 13.1 0.4 0.17 12.5 0.3 1.4 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like YicC_N PF03755.8 CEP07629.1 - 0.15 11.9 1.7 0.47 10.3 1.2 1.9 1 1 0 1 1 1 0 YicC-like family, N-terminal region GerPC PF10737.4 CEP07629.1 - 1.5 8.6 6.0 6.6 6.4 2.7 2.6 1 1 1 2 2 2 0 Spore germination protein GerPC DUF2075 PF09848.4 CEP07630.1 - 0.00085 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 CEP07630.1 - 0.0034 17.3 0.1 0.0058 16.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CEP07630.1 - 0.046 13.4 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CEP07630.1 - 0.056 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP07630.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 CEP07630.1 - 0.063 12.7 0.1 0.15 11.5 0.0 1.6 1 1 1 2 2 2 0 Sigma-54 interaction domain PIF1 PF05970.9 CEP07630.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF815 PF05673.8 CEP07630.1 - 0.08 11.8 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 CEP07630.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CEP07630.1 - 0.086 11.7 0.0 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 CEP07630.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CEP07630.1 - 0.12 11.9 2.3 0.21 11.1 0.5 2.0 1 1 1 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CEP07630.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Septin PF00735.13 CEP07630.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Septin IL3 PF02059.10 CEP07632.1 - 0.068 13.1 3.5 0.11 12.5 2.4 1.3 1 0 0 1 1 1 0 Interleukin-3 DUF1601 PF07671.6 CEP07632.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) PP2C PF00481.16 CEP07634.1 - 2.3e-53 181.1 0.0 3.8e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 CEP07634.1 - 1.4e-46 155.4 71.6 2.8e-08 33.1 0.2 13.1 4 3 6 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP07634.1 - 2.4e-38 129.6 60.3 2.7e-07 30.2 0.8 9.3 3 3 6 10 10 10 10 Leucine rich repeat Guanylate_cyc PF00211.15 CEP07634.1 - 2e-30 105.4 0.8 5e-30 104.2 0.0 2.1 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CEP07634.1 - 1.7e-25 85.1 64.5 0.22 11.6 0.1 20.8 19 1 2 21 21 21 10 Leucine Rich Repeat RA PF00788.18 CEP07634.1 - 5.6e-12 45.9 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 CEP07634.1 - 8.4e-08 31.1 66.5 1.6 9.2 0.1 18.0 19 0 0 19 19 19 4 Leucine rich repeat PP2C_2 PF13672.1 CEP07634.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_6 PF13516.1 CEP07634.1 - 1.1 9.5 0.0 1.1 9.5 0.0 15.1 18 1 1 19 19 19 0 Leucine Rich repeat Pkinase PF00069.20 CEP07635.1 - 3.2e-61 206.7 0.0 5.3e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07635.1 - 6.9e-46 156.4 0.0 1.1e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP07635.1 - 2.3e-08 33.3 0.0 4.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ADIP PF11559.3 CEP07635.1 - 0.0011 18.8 4.9 0.0022 17.8 3.4 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ABC1 PF03109.11 CEP07635.1 - 0.0095 15.8 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 ABC1 family DUF724 PF05266.9 CEP07635.1 - 0.017 14.7 1.4 0.033 13.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RNase_T PF00929.19 CEP07635.1 - 0.025 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 Exonuclease APH PF01636.18 CEP07635.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF972 PF06156.8 CEP07635.1 - 0.24 11.7 3.8 0.12 12.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CEP07635.1 - 0.36 10.3 6.4 0.39 10.2 2.2 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 CEP07635.1 - 1.3 9.3 7.4 0.81 10.0 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF760 PF05542.6 CEP07636.1 - 0.14 12.3 0.1 8.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF760) Kelch_3 PF13415.1 CEP07637.1 - 8.3e-48 159.5 12.5 9.3e-11 41.5 0.0 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP07637.1 - 7.3e-45 150.5 13.3 2.3e-08 33.6 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 CEP07637.1 - 7.9e-39 130.9 7.4 1.8e-07 30.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CEP07637.1 - 1.7e-37 126.0 11.6 1.5e-08 34.4 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_5 PF13854.1 CEP07637.1 - 7.1e-37 124.8 7.4 1.6e-08 34.2 0.6 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CEP07637.1 - 1.4e-31 106.9 16.6 8.6e-06 25.3 0.1 7.0 7 0 0 7 7 7 6 Kelch motif PQQ_3 PF13570.1 CEP07637.1 - 1.6e-05 24.9 3.3 0.78 10.1 0.0 4.8 5 0 0 5 5 5 2 PQQ-like domain ABC_membrane PF00664.18 CEP07638.1 - 7e-54 183.0 5.6 7e-54 183.0 3.9 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 CEP07638.1 - 7.8e-38 129.8 0.0 1.7e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CEP07638.1 - 1e-05 24.9 1.3 0.0061 15.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEP07638.1 - 1.2e-05 25.4 0.0 0.1 12.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CEP07638.1 - 8e-05 23.4 0.0 0.00017 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP07638.1 - 0.00016 21.8 0.1 0.0019 18.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP07638.1 - 0.00048 20.1 0.1 0.0022 17.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CEP07638.1 - 0.0032 16.9 0.0 0.099 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEP07638.1 - 0.0034 16.8 0.2 0.0099 15.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 CEP07638.1 - 0.015 14.9 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CEP07638.1 - 0.015 14.7 0.0 0.94 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.1 CEP07638.1 - 0.021 15.1 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEP07638.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEP07638.1 - 0.035 14.0 0.0 0.3 10.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain PAS_5 PF07310.8 CEP07638.1 - 0.071 12.6 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain AAA_30 PF13604.1 CEP07638.1 - 0.086 12.4 1.7 0.43 10.1 0.2 2.5 2 1 0 2 2 2 0 AAA domain Med22 PF06179.7 CEP07639.1 - 4.4e-22 78.1 3.7 5.5e-22 77.8 2.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Ead_Ea22 PF13935.1 CEP07639.1 - 0.019 15.2 0.9 0.18 12.1 0.5 1.9 1 1 1 2 2 2 0 Ead/Ea22-like protein AATF-Che1 PF13339.1 CEP07639.1 - 0.022 14.9 0.9 0.03 14.4 0.6 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor CDC37_N PF03234.9 CEP07639.1 - 0.058 13.7 1.2 0.072 13.4 0.9 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding PMC2NT PF08066.7 CEP07639.1 - 0.081 13.2 1.4 0.29 11.4 0.1 2.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain PP2C PF00481.16 CEP07641.1 - 4e-51 173.8 0.0 3.5e-43 147.8 0.0 2.7 1 1 1 2 2 2 2 Protein phosphatase 2C COOH-NH2_lig PF14395.1 CEP07641.1 - 0.098 11.7 0.0 27 3.6 0.0 3.5 4 0 0 4 4 4 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Fcf1 PF04900.7 CEP07642.1 - 2.1e-41 140.1 0.6 2.1e-41 140.1 0.4 1.8 2 0 0 2 2 2 1 Fcf1 Chromo PF00385.19 CEP07644.1 - 2.8e-09 36.4 0.7 5.4e-09 35.6 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mt_ATP-synt_D PF05873.7 CEP07645.1 - 6.6e-16 58.3 3.0 8.1e-16 58.0 2.1 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Baculo_PEP_C PF04513.7 CEP07645.1 - 0.0083 15.9 1.1 0.011 15.5 0.8 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 CEP07645.1 - 0.022 14.5 3.6 0.061 13.1 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vps51 PF08700.6 CEP07645.1 - 0.063 13.1 1.5 8.4 6.3 0.1 2.4 1 1 1 2 2 2 0 Vps51/Vps67 TMPIT PF07851.8 CEP07645.1 - 0.066 12.2 3.1 0.079 12.0 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cob_adeno_trans PF01923.13 CEP07645.1 - 0.069 12.9 1.3 0.097 12.4 0.2 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase SPX PF03105.14 CEP07645.1 - 0.1 12.3 2.1 0.11 12.2 1.2 1.3 1 1 0 1 1 1 0 SPX domain Laminin_II PF06009.7 CEP07645.1 - 0.15 11.8 5.7 0.31 10.7 1.7 2.4 1 1 2 3 3 3 0 Laminin Domain II Filament PF00038.16 CEP07645.1 - 0.16 11.4 4.5 1.4 8.3 0.9 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF327 PF03885.8 CEP07645.1 - 0.21 11.4 3.9 1.9 8.2 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF327) Phage_GP20 PF06810.6 CEP07645.1 - 0.25 10.7 7.7 0.49 9.8 0.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Prominin PF05478.6 CEP07645.1 - 0.27 8.7 4.4 0.3 8.5 3.1 1.0 1 0 0 1 1 1 0 Prominin Mer2 PF09074.5 CEP07645.1 - 0.28 11.0 4.6 0.45 10.4 3.2 1.4 1 1 0 1 1 1 0 Mer2 DUF4600 PF15372.1 CEP07645.1 - 0.29 11.3 4.7 3.5 7.8 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Allexi_40kDa PF05549.6 CEP07645.1 - 0.31 10.2 2.1 0.44 9.8 1.4 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF148 PF02520.12 CEP07645.1 - 0.32 10.8 5.2 0.57 9.9 2.4 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF148 Tropomyosin_1 PF12718.2 CEP07645.1 - 0.41 10.4 3.9 2.4 7.9 2.7 1.9 1 1 1 2 2 2 0 Tropomyosin like Spc7 PF08317.6 CEP07645.1 - 0.42 9.2 5.4 0.68 8.5 3.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.1 CEP07645.1 - 0.78 10.2 4.4 4.3 7.8 1.8 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2570 PF10828.3 CEP07645.1 - 1.6 8.3 8.1 15 5.2 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF948 PF06103.6 CEP07645.1 - 1.9 8.3 4.8 6.3 6.7 1.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 CEP07645.1 - 2.6 8.3 8.5 69 3.7 5.9 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PQ-loop PF04193.9 CEP07646.1 - 2.1e-19 68.8 17.6 4.9e-18 64.4 2.3 3.4 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 CEP07646.1 - 0.013 15.3 0.4 0.013 15.3 0.3 2.8 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange FliD_N PF02465.13 CEP07646.1 - 0.033 14.5 4.3 0.053 13.8 3.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus ERGIC_N PF13850.1 CEP07646.1 - 0.035 14.0 0.2 3.8 7.5 0.0 2.5 2 1 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) S1FA PF04689.8 CEP07646.1 - 0.049 13.5 0.0 0.049 13.5 0.0 2.0 2 0 0 2 2 2 0 DNA binding protein S1FA COX6A PF02046.10 CEP07646.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa PAT1 PF09770.4 CEP07647.1 - 1.6e-156 522.8 47.3 8.9e-143 477.3 21.0 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Lipase_GDSL PF00657.17 CEP07648.1 - 0.048 13.4 1.1 0.12 12.2 0.8 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ribosomal_L6e PF01159.14 CEP07649.1 - 1.5e-37 128.1 0.2 1.5e-37 128.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 CEP07649.1 - 7.6e-10 38.5 1.3 7.6e-10 38.5 0.9 2.1 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain F-box-like PF12937.2 CEP07650.1 - 0.00012 21.6 0.0 0.00041 20.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like Transket_pyr PF02779.19 CEP07651.1 - 6.7e-45 152.7 0.1 1.2e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CEP07651.1 - 1.8e-36 124.8 0.1 4.8e-36 123.4 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain MMtag PF10159.4 CEP07652.1 - 6.8e-34 115.7 3.0 6.8e-34 115.7 2.1 3.3 2 1 1 3 3 3 1 Kinase phosphorylation protein Hid1 PF12722.2 CEP07652.1 - 2.6 5.6 19.0 2.9 5.4 13.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF791 PF05631.9 CEP07653.1 - 1.3e-75 254.3 9.7 1.5e-75 254.0 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CEP07653.1 - 1.1e-18 67.0 29.3 1.7e-18 66.4 20.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ECF-ribofla_trS PF07155.7 CEP07653.1 - 0.95 9.1 16.2 0.031 14.0 4.1 2.5 1 1 1 2 2 2 0 ECF-type riboflavin transporter, S component Ribosomal_L4 PF00573.17 CEP07654.1 - 2.9e-69 232.3 0.0 3.7e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DEAD PF00270.24 CEP07655.1 - 1.6e-41 141.5 0.0 5.7e-41 139.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RanBP PF00641.13 CEP07655.1 - 6.9e-27 92.2 24.4 5.3e-10 38.2 1.6 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Helicase_C PF00271.26 CEP07655.1 - 2.8e-25 87.9 0.0 7.6e-25 86.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP07655.1 - 0.004 17.0 0.0 0.051 13.4 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CEP07655.1 - 0.02 13.3 0.0 1.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DZR PF12773.2 CEP07655.1 - 0.22 11.3 19.5 0.6 9.9 7.6 2.5 1 1 2 3 3 3 0 Double zinc ribbon zf-MIZ PF02891.15 CEP07655.1 - 5.9 6.4 8.1 5.7 6.5 0.5 3.0 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Rubredoxin PF00301.15 CEP07655.1 - 8.9 6.2 17.1 1.1 9.1 0.3 3.7 3 1 0 3 3 3 0 Rubredoxin Pkinase_Tyr PF07714.12 CEP07656.1 - 2.5e-25 89.0 0.0 3.6e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CEP07656.1 - 1.8e-23 83.0 0.0 3.2e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CEP07656.1 - 0.088 12.5 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cu-oxidase_3 PF07732.10 CEP07657.1 - 6.7e-10 38.7 1.0 1.9e-09 37.2 0.7 1.8 1 1 0 1 1 1 1 Multicopper oxidase CRAL_TRIO PF00650.15 CEP07659.1 - 2.6e-36 124.5 0.0 3.8e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP07659.1 - 2.3e-11 43.6 1.9 3.7e-11 42.9 0.0 2.3 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEP07659.1 - 1.8e-07 31.1 0.0 3.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF947 PF06102.7 CEP07660.1 - 1.9e-47 161.2 31.6 1.9e-47 161.2 21.9 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF947) DUF1748 PF08520.5 CEP07661.1 - 6.3e-30 102.6 0.0 7e-30 102.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WRKY PF03106.10 CEP07663.1 - 0.00024 20.8 6.6 0.0006 19.5 4.6 1.7 1 0 0 1 1 1 1 WRKY DNA -binding domain TFIIA PF03153.8 CEP07663.1 - 2.8 7.7 9.2 3.6 7.3 6.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L27e PF01777.13 CEP07664.1 - 2.2e-37 127.0 6.1 3.3e-37 126.4 4.2 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CEP07664.1 - 0.00054 19.5 6.3 0.0014 18.2 4.2 2.1 1 1 0 1 1 1 1 KOW motif Ribosomal_S2 PF00318.15 CEP07665.1 - 1.3e-32 112.7 2.9 7.9e-17 61.1 0.0 2.5 2 1 1 3 3 3 2 Ribosomal protein S2 Tfb2 PF03849.9 CEP07666.1 - 4.2e-145 483.0 6.3 5.1e-145 482.7 4.3 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CEP07666.1 - 2.1e-05 24.2 0.0 5.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSBP1 PF06825.7 CEP07666.1 - 0.049 13.2 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Phage_int_SAM_1 PF02899.12 CEP07669.1 - 0.002 18.2 1.1 0.0055 16.8 0.2 2.1 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 CEP07669.1 - 0.0052 17.0 1.0 0.028 14.7 0.1 2.3 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Aconitase_B_N PF11791.3 CEP07669.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Aconitate B N-terminal domain Asp_protease_2 PF13650.1 CEP07671.1 - 2.2e-05 24.8 0.0 4.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP07671.1 - 0.007 16.2 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Peptidase_A3 PF02160.10 CEP07671.1 - 0.0075 15.8 0.3 0.013 15.1 0.2 1.4 1 0 0 1 1 1 1 Cauliflower mosaic virus peptidase (A3) RVP_2 PF08284.6 CEP07671.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP07671.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pox_A_type_inc PF04508.7 CEP07671.1 - 0.58 10.0 2.0 1.3 8.9 0.8 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MFS_1 PF07690.11 CEP07676.1 - 1.4e-51 175.2 26.4 1.4e-51 175.2 18.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP07676.1 - 1.7e-12 46.7 9.6 1.7e-12 46.7 6.6 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter Steroid_dh PF02544.11 CEP07676.1 - 0.0069 16.1 1.1 0.07 12.8 0.3 2.4 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DAD PF02109.11 CEP07676.1 - 0.035 14.1 1.6 3.2 7.8 0.0 2.7 2 0 0 2 2 2 0 DAD family ESSS PF10183.4 CEP07676.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phage_holin_1 PF04531.8 CEP07676.1 - 4.6 7.3 6.8 1.9 8.6 0.2 3.0 2 1 0 2 2 2 0 Bacteriophage holin RseC_MucC PF04246.7 CEP07676.1 - 6 6.4 9.9 0.81 9.2 0.1 3.6 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC DnaJ PF00226.26 CEP07677.1 - 2.2e-14 52.9 0.0 3.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DOR PF14839.1 CEP07678.1 - 0.00092 19.0 0.0 0.0025 17.5 0.0 1.7 1 1 1 2 2 2 1 DOR family Ribosomal_L2_C PF03947.13 CEP07679.1 - 1.7e-48 163.6 0.7 3.2e-48 162.8 0.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CEP07679.1 - 4.3e-28 97.0 0.3 7.5e-28 96.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3374 PF11854.3 CEP07681.1 - 0.004 15.4 0.3 0.005 15.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3374) Mg_trans_NIPA PF05653.9 CEP07682.1 - 1.4e-22 80.0 18.4 8.2e-22 77.5 12.8 1.8 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CEP07682.1 - 8.4e-05 22.6 6.1 8.4e-05 22.6 4.3 2.9 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 CEP07682.1 - 0.0022 18.1 7.0 0.0022 18.1 4.9 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF3040 PF11239.3 CEP07682.1 - 0.47 10.5 5.2 1 9.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) UPF0197 PF05251.7 CEP07682.1 - 2.6 8.4 8.9 0.75 10.1 0.3 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0197) PhaG_MnhG_YufB PF03334.9 CEP07682.1 - 7.1 6.7 9.5 0.16 12.0 0.4 2.8 3 0 0 3 3 3 0 Na+/H+ antiporter subunit CUE PF02845.11 CEP07683.1 - 4.9e-07 29.1 0.0 1.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 CUE domain SR-25 PF10500.4 CEP07683.1 - 4.5 6.6 15.7 2.8 7.3 8.6 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Na_trans_assoc PF06512.8 CEP07683.1 - 6.5 6.6 12.1 7.9 6.3 7.4 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated Response_reg PF00072.19 CEP07684.1 - 4.3e-22 78.2 0.1 7.4e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain UFD1 PF03152.9 CEP07685.1 - 8.5e-45 152.0 0.0 1.6e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 CEP07685.1 - 0.0012 18.3 0.1 0.0057 16.2 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Antitoxin-MazE PF04014.13 CEP07685.1 - 0.024 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE zinc_ribbon_4 PF13717.1 CEP07685.1 - 0.038 13.6 10.0 0.044 13.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CEP07685.1 - 0.04 13.4 0.1 0.04 13.4 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain AUX_IAA PF02309.11 CEP07686.1 - 0.14 11.8 10.5 0.23 11.1 7.2 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF4614 PF15391.1 CEP07686.1 - 0.17 11.6 16.2 0.26 11.0 11.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF2201_N PF13203.1 CEP07686.1 - 0.29 10.2 5.4 0.39 9.8 3.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3827 PF12877.2 CEP07686.1 - 0.4 8.7 10.6 0.55 8.2 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) GCD14 PF08704.5 CEP07686.1 - 0.44 10.0 6.0 0.68 9.3 4.2 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Paramyxo_ncap PF00973.14 CEP07686.1 - 2.3 6.8 8.1 2.9 6.4 5.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Band_3_cyto PF07565.8 CEP07686.1 - 4 6.8 8.3 5.3 6.4 5.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2217 PF10265.4 CEP07686.1 - 4.3 5.9 11.5 5.3 5.6 8.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Fungal_trans PF04082.13 CEP07688.1 - 3.7e-24 85.0 1.8 3.7e-24 85.0 1.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP07688.1 - 0.00017 21.4 1.9 0.00035 20.4 1.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Y_phosphatase3 PF13350.1 CEP07690.1 - 1.2e-30 106.9 0.6 5.4e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CEP07690.1 - 1.8e-07 31.1 0.0 4.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 CEP07690.1 - 2.1e-07 30.4 0.0 8.7e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CEP07690.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF1219 PF06755.7 CEP07691.1 - 0.018 14.5 0.4 3.7 7.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1219) AstE_AspA PF04952.9 CEP07693.1 - 1e-35 123.0 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.6 CEP07693.1 - 6.2e-18 65.1 0.0 1.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 HutD Peptidase_M14 PF00246.19 CEP07693.1 - 1.7e-05 24.5 0.0 4.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Zinc carboxypeptidase SET PF00856.23 CEP07694.1 - 1.4e-08 35.2 0.2 1.4e-08 35.2 0.1 4.0 3 3 0 4 4 4 2 SET domain HSP70 PF00012.15 CEP07695.1 - 8.4e-264 876.0 13.1 9.6e-264 875.8 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP07695.1 - 1.8e-14 53.0 5.6 7e-13 47.8 1.5 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CEP07695.1 - 0.00099 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CEP07695.1 - 0.0015 18.3 7.4 0.84 9.4 0.0 4.4 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.13 CEP07695.1 - 0.016 14.3 3.0 0.11 11.5 0.2 2.9 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase PIF1 PF05970.9 CEP07696.1 - 0.0021 17.0 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase SNF2_N PF00176.18 CEP07697.1 - 2e-65 220.5 0.1 2e-65 220.5 0.0 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Chromo PF00385.19 CEP07697.1 - 2e-15 56.2 1.8 2.1e-08 33.7 0.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CEP07697.1 - 5.9e-13 48.4 2.0 7.1e-13 48.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 CEP07697.1 - 0.0089 16.0 1.2 0.42 10.7 0.0 3.9 4 0 0 4 4 4 1 Myb-like DNA-binding domain YfiO PF13525.1 CEP07698.1 - 0.0061 16.0 0.6 3.8 6.9 0.1 2.5 2 0 0 2 2 2 2 Outer membrane lipoprotein AAA PF00004.24 CEP07700.1 - 2.2e-39 134.6 0.2 2.1e-37 128.2 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP07700.1 - 4.8e-05 23.5 3.1 0.0033 17.5 0.1 3.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 CEP07700.1 - 6.9e-05 22.5 0.1 0.002 17.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEP07700.1 - 0.00022 20.3 0.0 0.00072 18.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CEP07700.1 - 0.00035 19.4 0.0 0.0012 17.6 0.0 1.9 1 1 1 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 CEP07700.1 - 0.00036 21.3 0.6 0.0021 18.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CEP07700.1 - 0.0015 18.3 0.0 0.0061 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP07700.1 - 0.0017 18.2 0.0 0.0077 16.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CEP07700.1 - 0.0024 17.2 0.0 0.0082 15.5 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CEP07700.1 - 0.0039 17.3 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CEP07700.1 - 0.0041 16.3 0.0 0.0081 15.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CEP07700.1 - 0.0044 16.7 0.3 0.04 13.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 CEP07700.1 - 0.0053 16.3 0.2 0.12 11.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CEP07700.1 - 0.0069 15.7 1.1 0.17 11.2 0.2 2.9 2 1 0 3 3 3 1 AAA domain AAA_28 PF13521.1 CEP07700.1 - 0.0074 16.2 0.0 0.027 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CEP07700.1 - 0.0085 15.7 0.8 0.15 11.6 0.0 3.3 2 2 1 3 3 3 1 NACHT domain AAA_2 PF07724.9 CEP07700.1 - 0.01 15.7 3.7 0.011 15.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 CEP07700.1 - 0.016 15.2 0.2 0.22 11.5 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.1 CEP07700.1 - 0.017 15.4 0.0 0.017 15.4 0.0 3.3 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 CEP07700.1 - 0.031 13.9 0.1 4.8 6.8 0.0 3.8 3 1 1 4 4 4 0 Archaeal ATPase AAA_16 PF13191.1 CEP07700.1 - 0.036 14.0 7.4 0.063 13.2 0.0 3.7 4 2 1 5 5 5 0 AAA ATPase domain ATP-synt_ab PF00006.20 CEP07700.1 - 0.045 13.2 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 CEP07700.1 - 0.12 11.5 0.3 2.3 7.2 0.1 2.4 1 1 1 2 2 2 0 KaiC FAR1 PF03101.10 CEP07701.1 - 0.011 16.2 1.6 0.02 15.4 1.1 1.5 1 1 0 1 1 1 0 FAR1 DNA-binding domain Chromo PF00385.19 CEP07702.1 - 0.098 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RRM_1 PF00076.17 CEP07703.1 - 5.9e-42 141.1 0.0 5.9e-17 61.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP07703.1 - 1.7e-25 88.7 0.0 5.9e-11 42.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07703.1 - 1.6e-22 79.1 0.0 4.6e-11 42.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.3 CEP07703.1 - 5e-05 22.7 1.7 0.00026 20.4 0.2 2.2 2 0 0 2 2 2 1 Spt20 family Med15 PF09606.5 CEP07703.1 - 0.00029 19.1 15.5 0.00033 19.0 10.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RRM_3 PF08777.6 CEP07703.1 - 0.00039 20.2 0.0 0.00039 20.2 0.0 2.7 2 1 0 2 2 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 CEP07703.1 - 0.00067 19.3 0.0 0.0085 15.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PAT1 PF09770.4 CEP07703.1 - 0.055 11.7 18.4 0.072 11.3 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CagX PF03524.10 CEP07703.1 - 0.06 12.6 5.2 0.11 11.8 3.6 1.3 1 0 0 1 1 1 0 Conjugal transfer protein Suf PF05843.9 CEP07703.1 - 0.14 11.8 10.3 0.035 13.8 4.8 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FimP PF09766.4 CEP07703.1 - 0.18 10.8 14.0 0.28 10.2 9.7 1.3 1 0 0 1 1 1 0 Fms-interacting protein Reprolysin_3 PF13582.1 CEP07703.1 - 0.19 12.2 4.9 2.9 8.4 1.1 3.1 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like DUF1178 PF06676.6 CEP07703.1 - 0.26 11.4 6.5 0.43 10.7 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF4175 PF13779.1 CEP07703.1 - 0.53 7.9 21.1 0.72 7.4 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.8 CEP07703.1 - 0.75 9.2 6.0 0.2 11.1 1.8 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 CEP07703.1 - 0.92 9.5 18.4 0.33 10.9 7.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.10 CEP07703.1 - 3.6 6.1 4.5 5.6 5.5 3.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4557 PF15101.1 CEP07703.1 - 4 7.2 13.8 7.8 6.2 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Spt5-NGN PF03439.8 CEP07704.1 - 1e-24 86.0 0.0 2.2e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CEP07704.1 - 5e-18 64.0 23.8 4.8e-06 26.0 0.1 7.1 7 1 0 7 7 7 4 KOW motif CTD PF12815.2 CEP07704.1 - 3e-14 53.5 53.9 2.3e-09 37.7 36.5 3.5 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 CEP07704.1 - 6.2e-10 39.5 11.9 6.2e-10 39.5 8.3 2.8 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal YCII PF03795.9 CEP07704.1 - 0.067 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 YCII-related domain Sulfotransfer_1 PF00685.22 CEP07704.1 - 0.075 12.2 0.0 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Sulfotransferase domain SPT6_acidic PF14632.1 CEP07704.1 - 3.3 7.9 33.9 0.019 15.0 9.2 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 MBOAT PF03062.14 CEP07705.1 - 7.1e-50 169.9 26.7 7.1e-50 169.9 18.5 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Flu_NS1 PF00600.14 CEP07707.1 - 0.054 12.6 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) OstA PF03968.9 CEP07707.1 - 0.08 12.8 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 OstA-like protein FAR1 PF03101.10 CEP07708.1 - 0.072 13.6 0.0 0.087 13.3 0.0 1.1 1 0 0 1 1 1 0 FAR1 DNA-binding domain HOOK PF05622.7 CEP07709.1 - 3e-52 177.4 75.6 4.3e-50 170.2 28.7 3.7 1 1 1 2 2 2 2 HOOK protein Reo_sigmaC PF04582.7 CEP07709.1 - 0.0041 16.3 19.7 0.049 12.7 1.0 4.4 2 1 4 6 6 6 4 Reovirus sigma C capsid protein HALZ PF02183.13 CEP07709.1 - 1.2 8.8 37.5 0.055 13.1 0.8 8.0 7 1 1 8 8 8 0 Homeobox associated leucine zipper GAS PF13851.1 CEP07709.1 - 3.7 6.6 84.9 0.013 14.6 3.3 6.0 1 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CEP07709.1 - 7.2 6.1 83.3 6.4 6.3 4.6 6.2 1 1 5 6 6 6 0 IncA protein 2-Hacid_dh_C PF02826.14 CEP07710.1 - 1.6e-60 203.2 0.0 2.2e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEP07710.1 - 2.4e-31 107.9 0.0 3e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CEP07710.1 - 2.5e-05 24.1 0.0 5.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CEP07710.1 - 3.3e-05 23.7 0.1 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 CEP07710.1 - 5.1e-05 22.7 0.0 0.00048 19.5 0.0 2.1 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 CEP07710.1 - 0.0023 18.0 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CEP07710.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CEP07710.1 - 0.027 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 CEP07710.1 - 0.045 13.5 1.2 0.31 10.8 0.2 2.4 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.13 CEP07710.1 - 0.054 13.4 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.1 CEP07710.1 - 0.072 13.3 0.0 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF3863 PF12979.2 CEP07711.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Bot1p PF12298.3 CEP07713.1 - 1.3e-28 100.0 0.2 2.4e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 CEP07713.1 - 1.4e-06 28.3 0.0 3.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.1 CEP07713.1 - 0.13 13.0 0.5 2.9 8.7 0.0 2.6 2 1 1 3 3 3 0 Homeodomain-like domain TIP49 PF06068.8 CEP07714.1 - 3e-186 618.9 4.7 3.5e-186 618.7 3.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CEP07714.1 - 2.7e-08 34.1 2.1 4e-05 23.8 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEP07714.1 - 1.8e-07 30.4 4.3 0.00039 19.5 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 CEP07714.1 - 1.7e-06 27.1 0.2 2.9e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CEP07714.1 - 2.3e-05 24.5 0.3 0.07 13.2 0.0 2.9 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CEP07714.1 - 4.5e-05 23.1 0.1 0.19 11.4 0.0 3.1 2 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CEP07714.1 - 0.00018 21.4 0.2 0.84 9.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CEP07714.1 - 0.00061 19.0 0.9 0.045 12.9 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CEP07714.1 - 0.00073 18.9 0.0 0.0021 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP07714.1 - 0.00076 19.5 0.0 0.0054 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 CEP07714.1 - 0.0019 17.7 0.2 3.7 7.0 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_19 PF13245.1 CEP07714.1 - 0.0078 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Parvo_NS1 PF01057.12 CEP07714.1 - 0.022 13.6 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 CEP07714.1 - 0.025 14.1 0.1 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CEP07714.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain GPI-anchored PF10342.4 CEP07715.1 - 5e-11 42.9 0.9 5e-11 42.9 0.6 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4156 PF13698.1 CEP07715.1 - 0.031 14.1 0.7 0.91 9.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4156) C2 PF00168.25 CEP07717.1 - 6.3e-23 80.4 0.2 8e-23 80.1 0.1 1.1 1 0 0 1 1 1 1 C2 domain DDE_3 PF13358.1 CEP07718.1 - 4.9e-06 26.3 0.0 1.4e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 CEP07718.1 - 3.6e-05 23.2 0.0 0.0001 21.7 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 CEP07718.1 - 9.1e-05 22.5 0.0 0.00028 20.9 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP07718.1 - 0.00021 20.8 0.0 0.0012 18.4 0.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 CEP07718.1 - 0.00055 19.8 0.1 0.0017 18.2 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.1 CEP07718.1 - 0.0037 16.8 0.1 0.054 13.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP07718.1 - 0.0038 17.4 0.0 0.0091 16.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain NUMOD1 PF07453.8 CEP07718.1 - 0.0089 15.8 0.0 0.033 14.0 0.0 2.0 1 0 0 1 1 1 1 NUMOD1 domain HTH_8 PF02954.14 CEP07718.1 - 0.0091 15.5 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.1 CEP07718.1 - 0.0092 15.5 0.1 0.053 13.1 0.0 2.1 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.2 CEP07718.1 - 0.03 13.9 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.15 CEP07718.1 - 0.057 13.1 0.0 0.49 10.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 CEP07718.1 - 0.068 12.5 0.5 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_1 PF00126.22 CEP07718.1 - 0.094 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_3 PF01381.17 CEP07718.1 - 0.098 12.5 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix MerR_1 PF13411.1 CEP07718.1 - 0.1 12.3 0.1 0.94 9.2 0.0 2.6 2 0 0 2 2 2 0 MerR HTH family regulatory protein MAM33 PF02330.11 CEP07719.1 - 5.7e-38 130.7 3.8 1.2e-37 129.7 2.7 1.5 1 1 0 1 1 1 1 Mitochondrial glycoprotein DUF3337 PF11816.3 CEP07720.1 - 5e-53 180.6 0.0 1.9e-43 149.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 CEP07720.1 - 2.7e-36 122.1 18.5 1.4e-10 40.5 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Peptidase_S9_N PF02897.10 CEP07722.1 - 9.9e-63 212.1 6.2 1.3e-62 211.7 4.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CEP07722.1 - 4.3e-53 179.6 0.0 7.8e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CEP07722.1 - 2.3e-05 24.4 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP07722.1 - 0.0006 19.4 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CEP07722.1 - 0.057 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 CEP07722.1 - 0.07 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold XkdN PF08890.6 CEP07722.1 - 0.074 12.8 0.0 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Phage XkdN-like protein AMP-binding PF00501.23 CEP07723.1 - 3e-38 131.2 0.0 1.7e-34 118.9 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AAA_16 PF13191.1 CEP07724.1 - 6e-09 36.1 0.5 5.7e-05 23.1 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain Guanylate_cyc PF00211.15 CEP07724.1 - 6.7e-05 22.3 0.1 0.033 13.5 0.0 3.3 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain AAA_17 PF13207.1 CEP07724.1 - 0.00054 20.7 0.0 0.0038 18.0 0.0 2.5 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 CEP07724.1 - 0.0035 16.2 0.0 1 8.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain IstB_IS21 PF01695.12 CEP07724.1 - 0.005 16.2 0.0 0.016 14.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CEP07724.1 - 0.0075 16.4 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 CEP07724.1 - 0.0099 16.0 1.8 0.083 13.0 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 CEP07724.1 - 0.016 14.6 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEP07724.1 - 0.025 14.8 0.8 0.13 12.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 CEP07724.1 - 0.071 12.3 0.1 0.45 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 CEP07724.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 CEP07724.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 CEP07724.1 - 1.2 9.0 5.6 1.7 8.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain Peptidase_C12 PF01088.16 CEP07725.1 - 8.5e-47 159.0 0.0 1.3e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 P63C PF10546.4 CEP07725.1 - 0.11 12.4 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 P63C domain GCR1_C PF12550.3 CEP07726.1 - 2.3e-21 75.4 3.6 8.3e-21 73.6 2.5 2.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_5 PF08360.6 CEP07726.1 - 0.0079 16.1 2.4 0.015 15.2 0.6 2.3 2 0 0 2 2 2 1 QacR-like protein, C-terminal region Flavi_capsid PF01003.14 CEP07726.1 - 0.22 11.0 1.3 2 7.9 0.1 2.5 2 0 0 2 2 2 0 Flavivirus capsid protein C Glyco_hydro_3_C PF01915.17 CEP07729.1 - 2.1e-22 79.7 0.1 3e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CEP07729.1 - 5.6e-05 22.9 0.0 0.00072 19.4 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 CEP07730.1 - 4.6e-86 288.4 0.1 6.5e-86 288.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CEP07730.1 - 4.4e-64 216.1 0.4 1.2e-63 214.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CEP07730.1 - 6.2e-21 74.1 0.0 1.2e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SPOC PF07744.8 CEP07731.1 - 0.0015 19.0 2.7 0.0043 17.5 0.3 2.5 2 0 0 2 2 2 1 SPOC domain zf-ZPR1 PF03367.8 CEP07731.1 - 0.043 12.9 9.3 0.044 12.9 0.3 4.2 3 2 1 5 5 5 0 ZPR1 zinc-finger domain PDEase_I_N PF08499.7 CEP07731.1 - 0.12 12.3 1.4 0.51 10.2 0.1 2.6 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Sec23_helical PF04815.10 CEP07731.1 - 0.27 10.6 6.9 0.26 10.7 0.3 3.9 3 2 2 5 5 5 0 Sec23/Sec24 helical domain PASTA PF03793.14 CEP07731.1 - 0.44 10.2 0.1 0.44 10.2 0.0 3.3 5 0 0 5 5 5 0 PASTA domain TrbC PF04956.8 CEP07731.1 - 0.85 9.6 4.7 0.57 10.2 0.1 2.8 2 0 0 2 2 2 0 TrbC/VIRB2 family Bac_DNA_binding PF00216.16 CEP07731.1 - 0.99 9.4 13.3 0.34 10.9 0.2 4.5 5 1 0 5 5 5 0 Bacterial DNA-binding protein DUF883 PF05957.8 CEP07731.1 - 4.7 7.6 27.5 0.61 10.5 2.2 5.9 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF883) FA_desaturase PF00487.19 CEP07732.1 - 4.5e-16 59.0 18.1 7.6e-16 58.3 12.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CEP07732.1 - 4.7e-11 42.3 0.1 1.2e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MerC PF03203.9 CEP07732.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 0 MerC mercury resistance protein Tic20 PF09685.5 CEP07732.1 - 0.12 12.3 1.5 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF4289 PF14121.1 CEP07733.1 - 0.0092 14.4 4.1 0.0095 14.3 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4289) DUF3513 PF12026.3 CEP07733.1 - 1.7 8.1 7.1 2 7.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) WD40 PF00400.27 CEP07734.1 - 2.1e-24 84.4 9.1 3.5e-09 36.2 0.0 5.5 5 2 0 5 5 5 4 WD domain, G-beta repeat zf-CCCH PF00642.19 CEP07735.1 - 7.2e-20 70.2 13.0 5.4e-10 38.7 3.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CEP07735.1 - 0.022 14.7 11.8 0.29 11.1 2.4 2.9 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type oligo_HPY PF08352.7 CEP07735.1 - 0.17 12.2 1.3 5.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Amidohydro_1 PF01979.15 CEP07736.1 - 4.4e-18 66.0 0.1 4.8e-17 62.6 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CEP07736.1 - 7.9e-12 45.7 0.1 3.3e-06 27.3 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CEP07736.1 - 2.2e-08 33.7 0.0 8.8e-08 31.8 0.0 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CEP07736.1 - 7.4e-06 25.4 0.3 2.1e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Macoilin PF09726.4 CEP07737.1 - 0.064 11.5 19.0 0.023 12.9 11.0 1.6 2 0 0 2 2 2 0 Transmembrane protein Virul_Fac PF10139.4 CEP07737.1 - 0.093 10.6 14.7 0.13 10.1 10.2 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor DUF572 PF04502.8 CEP07737.1 - 0.095 11.9 13.6 0.13 11.4 9.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Taq-exonuc PF09281.5 CEP07737.1 - 0.12 12.5 1.8 0.22 11.6 1.1 1.6 1 1 0 1 1 1 0 Taq polymerase, exonuclease Hid1 PF12722.2 CEP07737.1 - 0.7 7.4 18.3 0.93 7.0 12.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NifQ PF04891.7 CEP07737.1 - 2.1 8.4 11.6 0.16 12.1 4.4 1.7 2 0 0 2 2 2 0 NifQ TFIIA PF03153.8 CEP07737.1 - 2.2 8.0 20.0 2.9 7.6 13.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MPP6 PF10175.4 CEP07737.1 - 3.3 8.1 6.5 0.45 10.9 0.1 2.6 2 1 1 3 3 3 0 M-phase phosphoprotein 6 DNA_pol_viral_N PF00242.12 CEP07737.1 - 5 6.0 17.3 6.6 5.6 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain UNC-93 PF05978.11 CEP07738.1 - 2.7e-12 46.4 8.1 1e-11 44.5 5.6 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CEP07738.1 - 3.3e-12 45.7 41.1 3.3e-12 45.7 28.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3894 PF13033.1 CEP07738.1 - 0.039 13.9 1.1 0.039 13.9 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3894) T2SM PF04612.7 CEP07738.1 - 0.33 10.7 2.0 8.7 6.1 0.6 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M LAB_N PF07578.6 CEP07738.1 - 6 6.8 15.1 0.45 10.4 0.5 4.0 5 0 0 5 5 5 0 Lipid A Biosynthesis N-terminal domain Peptidase_M13 PF01431.16 CEP07739.1 - 3.4e-50 170.1 0.0 6.2e-50 169.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 CEP07739.1 - 2.8e-34 118.8 0.1 4.9e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.13 CEP07739.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M48 Sec16_C PF12931.2 CEP07740.1 - 3.9e-69 233.5 0.0 3.9e-69 233.5 0.0 1.7 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CEP07740.1 - 1.8e-21 76.2 0.4 4.8e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region DZR PF12773.2 CEP07740.1 - 0.00091 18.9 1.0 0.0018 18.0 0.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CEP07740.1 - 0.0092 15.4 3.2 0.017 14.5 2.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Tup_N PF08581.5 CEP07741.1 - 0.0084 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Tup N-terminal DUF3510 PF12022.3 CEP07741.1 - 0.02 15.0 2.1 0.028 14.5 1.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Peptidase_S64 PF08192.6 CEP07741.1 - 1.2 7.3 6.4 1.3 7.2 4.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mucin PF01456.12 CEP07741.1 - 6.1 6.6 15.3 7.1 6.3 10.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein CAF-1_p150 PF11600.3 CEP07741.1 - 7.7 5.8 6.8 9.9 5.4 4.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tup_N PF08581.5 CEP07742.1 - 0.0084 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Tup N-terminal DUF3510 PF12022.3 CEP07742.1 - 0.02 15.0 2.1 0.028 14.5 1.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Peptidase_S64 PF08192.6 CEP07742.1 - 1.2 7.3 6.4 1.3 7.2 4.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mucin PF01456.12 CEP07742.1 - 6.1 6.6 15.3 7.1 6.3 10.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein CAF-1_p150 PF11600.3 CEP07742.1 - 7.7 5.8 6.8 9.9 5.4 4.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Adaptin_N PF01602.15 CEP07743.1 - 7.9e-145 483.1 8.1 1e-144 482.7 5.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CEP07743.1 - 6.4e-11 42.3 6.7 0.0002 21.5 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CEP07743.1 - 1.3e-06 28.0 7.1 0.06 13.4 0.0 7.0 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.2 CEP07743.1 - 5.5e-06 26.3 4.3 0.0008 19.2 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CEP07743.1 - 7.5e-05 23.1 7.4 0.37 11.3 0.3 5.8 6 1 0 6 6 6 2 HEAT-like repeat Cohesin_HEAT PF12765.2 CEP07743.1 - 0.0082 16.0 0.0 0.031 14.2 0.0 2.0 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion DDHD PF02862.12 CEP07743.1 - 0.059 13.1 4.2 0.15 11.8 2.9 1.7 1 0 0 1 1 1 0 DDHD domain Arm PF00514.18 CEP07743.1 - 1.8 8.5 8.5 1.3 8.9 0.4 4.6 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat Trypan_PARP PF05887.6 CEP07743.1 - 8.6 6.1 13.3 24 4.7 9.2 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PH PF00169.24 CEP07744.1 - 1.6e-09 37.9 0.7 2.2e-08 34.2 0.0 3.2 2 1 0 2 2 2 1 PH domain PH_6 PF15406.1 CEP07744.1 - 0.053 13.5 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PspB PF06667.7 CEP07744.1 - 0.13 12.2 0.2 0.31 11.0 0.2 1.7 1 0 0 1 1 1 0 Phage shock protein B Aldedh PF00171.17 CEP07746.1 - 3.6e-166 553.0 1.3 6.5e-149 496.1 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 CEP07746.1 - 0.00019 20.7 0.1 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 CEP07746.1 - 0.0044 15.7 0.0 0.011 14.4 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Ank_2 PF12796.2 CEP07747.1 - 7.4e-41 138.3 0.0 2.2e-11 43.9 0.0 5.2 3 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP07747.1 - 1.5e-38 129.9 2.3 6.1e-11 42.1 0.0 6.2 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 CEP07747.1 - 2.8e-36 121.5 0.0 3.8e-06 26.4 0.0 8.5 8 2 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 CEP07747.1 - 5.3e-34 115.9 2.0 7.2e-07 29.5 0.1 7.3 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP07747.1 - 1.1e-23 80.9 5.0 0.0074 16.4 0.0 9.0 8 1 0 8 8 8 6 Ankyrin repeat AIG1 PF04548.11 CEP07748.1 - 3.2e-18 65.6 0.2 7.6e-18 64.3 0.1 1.6 1 1 0 1 1 1 1 AIG1 family Septin PF00735.13 CEP07748.1 - 1.2e-08 34.3 0.0 2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEP07748.1 - 1.2e-07 31.6 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEP07748.1 - 6e-06 26.1 0.7 0.01 15.6 0.1 2.4 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 CEP07748.1 - 0.0011 18.1 0.4 0.0099 15.0 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CEP07748.1 - 0.055 12.8 0.0 0.16 11.3 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Lin-8 PF03353.10 CEP07749.1 - 0.1 11.8 6.7 0.12 11.6 4.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2052 PF09747.4 CEP07749.1 - 0.23 11.3 6.2 0.3 11.0 4.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Macoilin PF09726.4 CEP07749.1 - 3.2 5.9 12.4 3.5 5.7 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein HSF_DNA-bind PF00447.12 CEP07750.1 - 8.1e-26 90.2 0.1 2.3e-25 88.7 0.1 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Zn_clus PF00172.13 CEP07750.1 - 1.2e-08 34.6 12.5 2.3e-08 33.7 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IncA PF04156.9 CEP07750.1 - 0.0052 16.4 6.3 0.0052 16.4 4.3 2.3 2 0 0 2 2 2 1 IncA protein DUF1212 PF06738.7 CEP07751.1 - 1.5e-33 115.9 11.5 4.6e-32 111.0 0.3 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CEP07751.1 - 1.8e-11 44.0 32.1 2.1e-09 37.3 6.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) CDK2AP PF09806.4 CEP07751.1 - 0.014 15.6 1.6 0.02 15.1 1.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF572 PF04502.8 CEP07752.1 - 4.2e-83 279.2 14.6 7.6e-83 278.4 9.4 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-ribbon_3 PF13248.1 CEP07752.1 - 0.029 13.5 0.5 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF866 PF05907.8 CEP07752.1 - 0.049 13.1 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zinc_ribbon_5 PF13719.1 CEP07752.1 - 0.12 11.9 0.5 3.4 7.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CEP07752.1 - 0.14 11.8 0.6 3.8 7.2 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Benyvirus_14KDa PF07255.6 CEP07752.1 - 0.15 11.9 0.9 1.1 9.0 0.0 2.3 2 1 1 3 3 3 0 Benyvirus 14KDa protein zf-dskA_traR PF01258.12 CEP07752.1 - 0.16 11.7 2.0 0.19 11.5 0.2 1.9 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger UPF0547 PF10571.4 CEP07752.1 - 0.34 10.6 1.4 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.7 CEP07752.1 - 0.36 10.1 2.7 3.3 7.1 0.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Mut7-C PF01927.11 CEP07752.1 - 0.4 10.6 4.2 15 5.5 0.1 2.8 2 1 1 3 3 3 0 Mut7-C RNAse domain Rubredoxin PF00301.15 CEP07752.1 - 0.42 10.5 2.2 3 7.8 1.5 2.3 1 1 0 1 1 1 0 Rubredoxin zf-NADH-PPase PF09297.6 CEP07752.1 - 0.88 9.1 3.0 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF3449 PF11931.3 CEP07752.1 - 4.2 6.8 7.5 0.96 8.9 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) MFS_1 PF07690.11 CEP07753.1 - 1.1e-17 63.7 17.6 1.8e-17 63.0 5.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.6 CEP07753.1 - 2.8 7.8 6.0 5.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Arrestin_N PF00339.24 CEP07754.1 - 1.9e-06 27.7 3.7 0.0081 15.9 0.0 4.0 2 2 2 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP07754.1 - 6e-05 23.1 9.2 0.03 14.4 0.6 2.9 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain DUF748 PF05359.6 CEP07754.1 - 0.097 12.6 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF748) MFS_1 PF07690.11 CEP07755.1 - 2.1e-45 154.9 34.4 2.1e-45 154.9 23.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP07755.1 - 2.2e-20 72.6 13.3 2.2e-20 72.6 9.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Wzz PF02706.10 CEP07755.1 - 0.081 12.7 0.0 0.081 12.7 0.0 2.6 3 0 0 3 3 3 0 Chain length determinant protein zf-DHHC PF01529.15 CEP07755.1 - 0.53 9.6 6.4 7.6 5.8 2.0 3.2 3 1 0 3 3 3 0 DHHC palmitoyltransferase Ribosomal_S8 PF00410.14 CEP07756.1 - 2.5e-28 98.4 0.0 3e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Amidohydro_2 PF04909.9 CEP07757.1 - 1.3e-25 90.4 0.0 1.8e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Sec20 PF03908.8 CEP07758.1 - 0.0014 18.2 1.9 0.0017 18.0 1.3 1.2 1 0 0 1 1 1 1 Sec20 SMK-1 PF04802.10 CEP07758.1 - 0.006 16.1 0.8 0.0067 15.9 0.6 1.0 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DivIC PF04977.10 CEP07758.1 - 0.018 14.5 1.5 0.024 14.1 1.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Rho_Binding PF08912.6 CEP07758.1 - 0.023 14.9 1.0 0.037 14.3 0.7 1.6 1 1 0 1 1 1 0 Rho Binding Jnk-SapK_ap_N PF09744.4 CEP07758.1 - 0.027 14.4 1.6 0.031 14.2 1.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.4 CEP07758.1 - 0.027 13.0 2.1 0.031 12.8 1.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Drf_FH3 PF06367.11 CEP07758.1 - 0.028 13.8 1.3 0.037 13.4 0.9 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain Phage_GP20 PF06810.6 CEP07758.1 - 0.033 13.6 3.4 0.04 13.3 2.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 FadA PF09403.5 CEP07758.1 - 0.089 12.8 1.1 0.11 12.5 0.8 1.1 1 0 0 1 1 1 0 Adhesion protein FadA zf-C4H2 PF10146.4 CEP07758.1 - 0.13 12.2 2.0 0.14 12.1 1.4 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Occludin_ELL PF07303.8 CEP07758.1 - 0.14 12.9 0.9 0.17 12.6 0.7 1.2 1 0 0 1 1 1 0 Occludin homology domain Seryl_tRNA_N PF02403.17 CEP07758.1 - 0.15 12.1 2.4 0.18 11.8 1.7 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.7 CEP07758.1 - 0.15 12.4 2.2 2.2 8.6 0.3 2.0 1 1 1 2 2 2 0 SlyX BLOC1_2 PF10046.4 CEP07758.1 - 0.15 12.2 2.5 0.33 11.1 1.7 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 STAT_alpha PF01017.15 CEP07758.1 - 0.19 11.4 1.6 0.22 11.2 1.1 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain TMF_DNA_bd PF12329.3 CEP07758.1 - 0.27 11.0 5.3 0.16 11.7 1.5 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HR1 PF02185.11 CEP07758.1 - 1 9.1 6.6 9.2 6.0 4.5 2.0 1 1 0 1 1 1 0 Hr1 repeat FTHFS PF01268.14 CEP07759.1 - 8.2e-265 879.0 0.1 1.1e-264 878.5 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CEP07759.1 - 1.7e-67 225.4 2.8 4.1e-67 224.2 1.9 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CEP07759.1 - 1.1e-41 141.5 3.0 3.7e-40 136.6 1.7 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 CEP07759.1 - 0.05 13.4 2.5 3.5 7.4 1.7 2.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rad9 PF04139.8 CEP07760.1 - 1.1e-37 129.5 0.1 1.4e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 CEP07760.1 - 0.015 14.2 0.1 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Hus1-like protein Ricin_B_lectin PF00652.17 CEP07761.1 - 1.4e-07 31.5 0.3 3.9e-07 30.1 0.2 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP07761.1 - 0.00088 19.6 1.0 0.93 9.8 0.2 2.7 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Hexokinase_2 PF03727.11 CEP07762.1 - 1.7e-59 200.9 0.1 2.5e-59 200.4 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEP07762.1 - 2.1e-41 141.5 0.0 3.7e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Cullin PF00888.17 CEP07763.1 - 1.6e-124 416.6 8.6 1.6e-124 416.6 6.0 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CEP07763.1 - 1.5e-25 88.7 5.1 2.1e-25 88.3 2.4 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain NCD2 PF04905.8 CEP07764.1 - 9.2e-05 22.2 0.0 9.2e-05 22.2 0.0 3.4 1 1 3 4 4 4 1 NAB conserved region 2 (NCD2) NCD1 PF04904.8 CEP07764.1 - 0.0051 16.5 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) SAM_1 PF00536.25 CEP07764.1 - 0.044 13.9 0.2 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NAD_binding_2 PF03446.10 CEP07766.1 - 7.5e-34 116.9 0.0 1.4e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CEP07766.1 - 6e-10 39.2 0.0 1.4e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CEP07766.1 - 3.7e-08 33.7 0.1 8.9e-07 29.2 0.0 2.4 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CEP07766.1 - 5.9e-05 23.1 0.1 0.00027 21.0 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 CEP07766.1 - 0.00023 20.9 0.3 0.0011 18.6 0.1 2.2 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPOR PF05036.8 CEP07766.1 - 0.024 14.7 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Sporulation related domain 3HCDH_N PF02737.13 CEP07766.1 - 4.2 6.9 7.7 2.5 7.7 0.1 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Catalase PF00199.14 CEP07767.1 - 2.9e-152 506.8 0.2 5.1e-152 506.0 0.2 1.4 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CEP07767.1 - 6.7e-19 67.5 0.0 1.4e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 CEP07767.1 - 1.3e-06 27.9 0.0 2.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Phage_lysis PF03245.8 CEP07768.1 - 5.4 7.0 28.6 30 4.6 19.8 2.3 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein TMPIT PF07851.8 CEP07768.1 - 7.3 5.5 13.2 14 4.6 9.2 1.6 1 0 0 1 1 1 0 TMPIT-like protein AIG1 PF04548.11 CEP07769.1 - 3.2e-16 59.0 0.0 5.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 CEP07769.1 - 1.9e-09 37.4 0.0 3.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP07769.1 - 3.6e-05 22.9 0.0 7.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CEP07769.1 - 0.00014 21.6 0.3 0.19 11.5 0.1 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.13 CEP07769.1 - 0.00018 20.6 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Septin ABC_tran PF00005.22 CEP07769.1 - 0.0073 16.6 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 CEP07769.1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Miro PF08477.8 CEP07769.1 - 0.055 13.9 0.2 0.3 11.6 0.1 2.2 1 1 0 1 1 1 0 Miro-like protein FR47 PF08445.5 CEP07771.1 - 0.0026 17.4 0.1 0.027 14.2 0.1 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CEP07771.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP07771.1 - 0.027 14.4 0.0 0.062 13.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP07771.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAP2 PF01569.16 CEP07772.1 - 3.7e-19 68.6 3.3 3.7e-19 68.6 2.3 2.0 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_S11 PF00411.14 CEP07773.1 - 5.6e-41 139.1 0.3 7.2e-41 138.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Anp1 PF03452.9 CEP07774.1 - 1.5e-80 270.2 0.0 1.9e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CEP07774.1 - 0.00012 21.8 0.1 0.002 17.8 0.0 2.1 1 1 1 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CEP07774.1 - 0.054 13.2 0.0 0.22 11.2 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Pex16 PF08610.5 CEP07775.1 - 4.1e-78 262.7 5.4 4.8e-78 262.5 3.8 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Choline_kinase PF01633.15 CEP07775.1 - 0.094 12.2 0.3 6.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase PRELI PF04707.9 CEP07776.1 - 3.3e-47 159.9 0.2 4e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Methyltransf_11 PF08241.7 CEP07777.1 - 1.8e-14 54.0 0.0 3.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP07777.1 - 4.4e-13 49.0 0.0 5.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP07777.1 - 7.8e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP07777.1 - 2.8e-08 34.0 0.0 6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP07777.1 - 3.3e-08 34.0 0.0 7.8e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP07777.1 - 4e-08 32.6 0.0 5.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 CEP07777.1 - 4.2e-08 32.5 0.0 5.4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CEP07777.1 - 4.4e-07 30.3 0.0 7.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CEP07777.1 - 1.3e-05 24.9 0.0 2.2e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.14 CEP07777.1 - 0.00085 19.3 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.6 CEP07777.1 - 0.0032 16.9 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.12 CEP07777.1 - 0.0078 15.2 0.0 0.071 12.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 CEP07777.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEP07777.1 - 0.065 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Pox_MCEL PF03291.11 CEP07777.1 - 0.091 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Pkinase PF00069.20 CEP07778.1 - 6.1e-60 202.5 0.0 1.4e-37 129.3 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07778.1 - 1.6e-29 102.7 0.0 3e-22 78.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PAS_9 PF13426.1 CEP07778.1 - 9.4e-05 22.7 0.6 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 1 PAS domain Kinase-like PF14531.1 CEP07778.1 - 0.00056 18.9 0.0 0.0039 16.1 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CEP07778.1 - 0.0013 18.5 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS PF00989.19 CEP07778.1 - 0.01 15.6 0.0 0.01 15.6 0.0 2.3 3 0 0 3 3 3 1 PAS fold Seadorna_VP7 PF07387.6 CEP07778.1 - 0.046 12.5 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 CEP07778.1 - 1.2 7.8 0.0 2 7.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ifi-6-16 PF06140.8 CEP07779.1 - 8.4e-10 38.3 15.2 1.3e-09 37.6 10.4 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family GRIP PF01465.15 CEP07780.1 - 7.9e-16 57.2 0.1 2.5e-15 55.6 0.1 2.0 1 0 0 1 1 1 1 GRIP domain PXA PF02194.10 CEP07781.1 - 6e-22 78.0 6.8 9.5e-22 77.4 0.1 3.1 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 CEP07781.1 - 9.7e-09 35.3 1.6 3.4e-08 33.5 0.0 2.7 2 1 1 3 3 3 1 Sorting nexin C terminal Serinc PF03348.10 CEP07781.1 - 0.028 13.1 3.1 0.04 12.6 2.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3048 PF11258.3 CEP07781.1 - 0.057 12.5 1.7 0.088 11.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) DUF4519 PF15012.1 CEP07781.1 - 0.19 11.6 1.8 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Mucin PF01456.12 CEP07781.1 - 0.25 11.0 19.7 0.41 10.4 13.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein HTH_29 PF13551.1 CEP07782.1 - 0.00014 21.9 0.0 0.00084 19.4 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP07782.1 - 0.0013 19.5 0.0 0.0046 17.7 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.1 CEP07782.1 - 0.0026 17.5 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_24 PF13412.1 CEP07782.1 - 0.011 15.0 0.0 0.054 12.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 CEP07782.1 - 0.029 13.8 0.0 0.081 12.4 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Transposase_24 PF03004.9 CEP07782.1 - 0.059 13.2 0.5 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) TSKS PF15358.1 CEP07783.1 - 0.44 8.6 1.8 0.47 8.5 1.3 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate PH PF00169.24 CEP07785.1 - 4.7e-09 36.3 0.1 1.9e-08 34.4 0.1 2.1 1 0 0 1 1 1 1 PH domain Lyase_1 PF00206.15 CEP07786.1 - 1.1e-117 392.6 0.0 1.9e-117 391.9 0.0 1.4 2 0 0 2 2 2 1 Lyase FumaraseC_C PF10415.4 CEP07786.1 - 6.1e-24 83.8 0.0 1.1e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus OrfB_Zn_ribbon PF07282.6 CEP07788.1 - 0.0001 21.8 0.1 0.00022 20.7 0.1 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Pkinase PF00069.20 CEP07789.1 - 9.8e-72 241.2 0.0 1.2e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07789.1 - 1.1e-30 106.6 0.0 1.7e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP07789.1 - 0.0057 15.6 0.0 0.0079 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CEP07789.1 - 0.015 14.1 0.1 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CEP07789.1 - 0.02 14.6 0.3 0.031 14.0 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DELLA PF12041.3 CEP07789.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal WD40 PF00400.27 CEP07790.1 - 5.4e-10 38.7 0.0 3.3e-06 26.7 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat adh_short PF00106.20 CEP07791.1 - 5.9e-31 107.6 0.1 8.8e-31 107.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP07791.1 - 1.7e-25 90.1 0.0 2.2e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP07791.1 - 1.2e-10 41.3 0.1 4.3e-10 39.5 0.1 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 CEP07791.1 - 0.0001 21.7 0.0 0.0002 20.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEP07791.1 - 0.011 15.7 0.1 0.019 14.9 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 CEP07791.1 - 0.095 12.7 0.1 0.38 10.8 0.1 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PTPA PF03095.10 CEP07792.1 - 0.0012 18.1 0.4 0.003 16.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotyrosyl phosphate activator (PTPA) protein Peptidase_C80 PF11713.3 CEP07792.1 - 0.057 13.2 0.1 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C80 family DUF2520 PF10728.4 CEP07793.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Asp PF00026.18 CEP07795.1 - 1.8e-68 231.1 1.1 2.1e-68 230.8 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP07795.1 - 2.8e-11 43.6 0.1 4.9e-09 36.3 0.1 3.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP07795.1 - 5.8e-06 25.9 0.1 1.4e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CEP07795.1 - 0.021 15.3 0.3 0.5 10.9 0.1 3.1 3 1 0 3 3 3 0 Aspartyl protease DeoRC PF00455.17 CEP07795.1 - 0.027 14.1 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 DeoR C terminal sensor domain Asp PF00026.18 CEP07796.1 - 7.5e-13 48.4 0.0 2.1e-09 37.1 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease DUF663 PF04950.7 CEP07797.1 - 3.6e-91 305.2 0.0 3.6e-91 305.2 0.0 2.5 3 0 0 3 3 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CEP07797.1 - 3.7e-30 103.2 0.0 1.4e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CEP07797.1 - 9e-08 31.7 0.0 4.9e-05 22.8 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 CEP07797.1 - 9.3e-06 26.4 0.0 9.3e-06 26.4 0.0 3.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CEP07797.1 - 1.4e-05 25.1 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CEP07797.1 - 2.2e-05 24.6 0.0 8.9e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CEP07797.1 - 9.4e-05 22.9 0.0 0.0004 20.8 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_33 PF13671.1 CEP07797.1 - 0.0001 22.2 0.0 0.00029 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CEP07797.1 - 0.00017 21.3 0.1 0.00064 19.4 0.0 2.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CEP07797.1 - 0.00018 21.7 0.0 0.00053 20.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CEP07797.1 - 0.0003 20.7 0.2 0.0025 17.7 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CEP07797.1 - 0.0012 18.3 0.0 0.0037 16.7 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 CEP07797.1 - 0.0017 18.6 0.0 0.0017 18.6 0.0 4.0 3 1 0 3 3 1 1 AAA domain AAA_19 PF13245.1 CEP07797.1 - 0.0024 17.6 0.1 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 CEP07797.1 - 0.0034 17.5 0.0 0.015 15.4 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 CEP07797.1 - 0.0057 16.6 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CEP07797.1 - 0.0061 16.8 0.0 0.0061 16.8 0.0 3.1 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.7 CEP07797.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 CEP07797.1 - 0.03 13.7 0.0 0.091 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CEP07797.1 - 0.035 13.8 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 CEP07797.1 - 0.046 13.1 0.0 0.099 12.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CEP07797.1 - 0.079 11.7 0.0 0.29 9.8 0.0 1.9 1 0 0 1 1 1 0 ArgK protein Viral_helicase1 PF01443.13 CEP07797.1 - 0.18 11.3 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.18 CEP07797.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.6 3 1 1 4 4 4 0 Dynamin family Peroxin-22 PF12827.2 CEP07798.1 - 0.0048 16.5 0.4 0.011 15.4 0.3 1.7 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family Asp PF00026.18 CEP07799.1 - 1.1e-59 202.3 0.5 2e-59 201.4 0.3 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP07799.1 - 1e-10 41.7 0.6 3.3e-10 40.1 0.3 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEP07799.1 - 0.064 13.7 0.1 9.5 6.7 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease Asp PF00026.18 CEP07800.1 - 6e-75 252.4 5.7 2.7e-73 246.9 4.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP07800.1 - 9.9e-09 35.3 2.4 1.9e-07 31.1 1.0 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP07800.1 - 0.00012 21.6 0.1 0.00079 19.0 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CEP07800.1 - 0.0011 19.4 0.8 1.4 9.4 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease Adenylsucc_synt PF00709.16 CEP07801.1 - 3.8e-166 552.9 0.0 4.3e-166 552.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF2095 PF09868.4 CEP07801.1 - 0.081 12.6 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) Sugar_tr PF00083.19 CEP07802.1 - 8.5e-132 439.9 30.7 1e-131 439.6 21.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP07802.1 - 6.8e-34 117.1 62.7 1.5e-26 92.9 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 CEP07802.1 - 0.00032 18.9 0.6 0.00032 18.9 0.4 2.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.20 CEP07803.1 - 4.7e-69 232.4 0.0 7.3e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP07803.1 - 9.7e-35 119.8 0.0 2.1e-34 118.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP07803.1 - 0.0014 17.6 0.0 0.0027 16.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP07803.1 - 0.032 13.3 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arrestin_N PF00339.24 CEP07804.1 - 3.4e-15 56.1 0.1 2.2e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP07804.1 - 8.8e-06 25.8 0.0 2.6e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DDRGK PF09756.4 CEP07806.1 - 6.2e-12 45.3 30.7 6.2e-12 45.3 21.3 2.0 2 1 0 2 2 2 1 DDRGK domain HTH_26 PF13443.1 CEP07806.1 - 0.004 17.3 0.1 0.0091 16.1 0.1 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain TMEM154 PF15102.1 CEP07806.1 - 0.06 13.0 0.1 0.06 13.0 0.1 2.4 2 1 0 2 2 2 0 TMEM154 protein family Put_Phosphatase PF06888.7 CEP07806.1 - 0.08 12.0 2.1 0.48 9.5 0.1 2.1 1 1 1 2 2 2 0 Putative Phosphatase DUF1180 PF06679.7 CEP07806.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CAF-1_p150 PF11600.3 CEP07806.1 - 0.31 10.3 42.2 0.43 9.9 29.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal V_ATPase_I PF01496.14 CEP07806.1 - 2.4 5.9 16.5 6.1 4.5 10.0 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.11 CEP07806.1 - 3 7.6 7.8 6.1 6.6 5.4 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ETRAMP PF09716.5 CEP07806.1 - 3 7.8 6.2 45 4.0 4.3 2.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4220 PF13968.1 CEP07806.1 - 4.2 6.3 5.3 5 6.1 3.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) DUF342 PF03961.8 CEP07806.1 - 5.1 5.3 15.4 6.9 4.9 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ank_2 PF12796.2 CEP07807.1 - 3.5e-15 56.0 0.0 7.1e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEP07807.1 - 1.3e-13 50.0 0.7 1e-05 25.0 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CEP07807.1 - 5.6e-12 44.6 0.0 0.00085 19.3 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CEP07807.1 - 8.1e-09 35.4 0.4 0.0002 21.4 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP07807.1 - 1.1e-07 32.1 0.1 5e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) NTP_transf_5 PF14907.1 CEP07807.1 - 0.044 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Isochorismatase PF00857.15 CEP07808.1 - 8.1e-28 97.5 0.1 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF1481 PF07356.7 CEP07808.1 - 0.033 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) DUF2070 PF09843.4 CEP07808.1 - 0.087 12.2 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) SCP2 PF02036.12 CEP07809.1 - 4.3e-09 36.5 0.1 6.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family DUF500 PF04366.7 CEP07810.1 - 7.8e-43 144.9 0.1 1.2e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CEP07810.1 - 3.1e-14 52.0 0.0 7.8e-14 50.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP07810.1 - 7.6e-13 47.7 0.0 1.5e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CEP07810.1 - 7.8e-13 47.7 0.0 1.5e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ACOX PF01756.14 CEP07812.1 - 7.8e-40 136.2 0.0 1.6e-39 135.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEP07812.1 - 1.7e-26 92.9 2.5 1.7e-26 92.9 1.7 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEP07812.1 - 1e-10 40.9 0.2 2.4e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEP07812.1 - 9.7e-06 25.7 0.0 8.9e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CEP07812.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain RHD3 PF05879.7 CEP07813.1 - 9e-253 840.5 20.4 2e-249 829.4 14.2 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 CEP07813.1 - 4e-06 26.0 1.4 5.7e-06 25.5 0.2 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 CEP07813.1 - 5.9e-06 26.2 1.4 1e-05 25.4 0.0 2.1 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CEP07813.1 - 5e-05 23.2 0.0 0.00015 21.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CEP07813.1 - 0.00011 22.7 0.0 0.00035 21.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein NAAA-beta PF15508.1 CEP07813.1 - 0.019 15.3 1.6 0.097 13.0 0.2 2.9 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAA_28 PF13521.1 CEP07813.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CEP07813.1 - 0.063 12.4 0.1 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RmlD_sub_bind PF04321.12 CEP07814.1 - 5.6e-57 192.8 0.0 1.5e-55 188.1 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 CEP07814.1 - 2.1e-24 86.2 0.0 2.7e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEP07814.1 - 1.4e-11 44.7 0.0 1.9e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CEP07814.1 - 3.9e-09 35.8 0.0 9.8e-08 31.2 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 CEP07814.1 - 1.1e-06 27.7 0.1 2.4e-05 23.4 0.1 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CEP07814.1 - 2.5e-05 24.2 1.7 0.00091 19.1 1.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 CEP07814.1 - 9.6e-05 21.2 0.0 0.00029 19.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CEP07814.1 - 0.00061 19.7 0.8 0.0044 16.9 0.1 2.3 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 CEP07814.1 - 0.075 12.2 0.1 0.28 10.3 0.0 1.9 2 1 0 2 2 2 0 NmrA-like family CH PF00307.26 CEP07815.1 - 4.9e-73 242.1 0.3 8e-20 70.8 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CEP07815.1 - 2.8e-14 52.5 0.0 9.6e-05 21.9 0.0 4.2 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_6 PF13405.1 CEP07815.1 - 3.2e-05 23.4 1.0 0.029 14.2 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CEP07815.1 - 0.00011 21.2 0.6 1.2 8.6 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CEP07815.1 - 0.00016 21.7 1.2 0.00031 20.8 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CEP07815.1 - 0.026 13.8 0.6 8.7 5.8 0.1 2.9 2 0 0 2 2 2 0 EF hand MARVEL PF01284.18 CEP07816.1 - 0.043 13.6 11.5 0.1 12.4 8.0 1.7 1 1 0 1 1 1 0 Membrane-associating domain TPR_11 PF13414.1 CEP07819.1 - 1.2e-18 66.5 2.8 2.5e-14 52.6 0.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CEP07819.1 - 2.5e-12 45.8 5.5 0.00015 21.1 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP07819.1 - 1.1e-05 24.9 1.8 1.2 9.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP07819.1 - 0.00088 19.1 0.4 2.3 8.1 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP07819.1 - 0.00089 19.2 0.1 0.0048 16.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEP07819.1 - 0.0035 17.6 0.1 0.11 12.8 0.0 2.5 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF3808 PF10300.4 CEP07819.1 - 0.0066 15.0 1.6 0.0098 14.4 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Apc3 PF12895.2 CEP07819.1 - 0.027 14.6 3.2 0.056 13.5 2.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SpoU_sub_bind PF08032.7 CEP07819.1 - 0.9 9.7 4.4 2.4 8.3 3.1 1.7 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Scramblase PF03803.10 CEP07820.1 - 1.2e-53 181.4 0.2 1.7e-53 180.9 0.1 1.2 1 0 0 1 1 1 1 Scramblase Indigoidine_A PF04227.7 CEP07821.1 - 4.3e-124 413.4 5.3 5.1e-124 413.2 3.7 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein TPP_enzyme_N PF02776.13 CEP07821.1 - 0.0055 16.2 0.5 0.029 13.8 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transglut_core PF01841.14 CEP07821.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily PX PF00787.19 CEP07822.1 - 6.8e-22 77.4 2.6 9.3e-22 76.9 0.9 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CEP07822.1 - 6.2e-12 45.2 5.1 2.4e-07 30.2 0.1 2.4 2 0 0 2 2 2 2 Vps5 C terminal like BLOC1_2 PF10046.4 CEP07822.1 - 0.03 14.4 1.6 0.85 9.7 0.0 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4625 PF15418.1 CEP07823.1 - 0.00085 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) rve PF00665.21 CEP07825.1 - 1.1e-11 44.8 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Poxvirus_B22R_N PF13169.1 CEP07825.1 - 0.13 12.4 0.1 0.28 11.3 0.0 1.5 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal DNA_pol_A_exo1 PF01612.15 CEP07827.1 - 3.8e-05 23.2 0.0 9.2e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease SopA PF13981.1 CEP07827.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 SopA-like central domain Nucleoplasmin PF03066.10 CEP07830.1 - 0.16 11.4 0.1 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin Tubulin-binding PF00418.14 CEP07834.1 - 4.6e-77 253.3 52.9 3e-11 42.7 0.9 8.5 8 0 0 8 8 8 8 Tau and MAP protein, tubulin-binding repeat ATP-synt_ab PF00006.20 CEP07834.1 - 1.4e-61 207.7 0.0 2.5e-61 206.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEP07834.1 - 5.3e-16 59.1 0.3 1.3e-15 57.8 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEP07834.1 - 1.2e-08 34.9 0.5 2.8e-08 33.8 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CEP07834.1 - 0.067 13.0 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 HAS barrel domain HrcA_DNA-bdg PF03444.10 CEP07834.1 - 2.3 7.6 5.7 20 4.7 0.0 4.4 6 0 0 6 6 6 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Arrestin_N PF00339.24 CEP07835.1 - 1.1e-10 41.5 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Homeobox PF00046.24 CEP07836.1 - 9.1e-21 73.2 2.1 2.6e-20 71.7 1.4 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP07836.1 - 0.00056 19.5 1.3 0.0057 16.3 0.2 2.6 2 0 0 2 2 2 1 Homeobox KN domain PAD_N PF08526.5 CEP07836.1 - 0.068 13.2 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain Mito_fiss_reg PF05308.6 CEP07836.1 - 1.5 8.1 26.3 0.5 9.6 4.3 2.8 2 1 0 2 2 2 0 Mitochondrial fission regulator Tubulin PF00091.20 CEP07837.1 - 9.1e-71 238.1 0.0 1.2e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEP07837.1 - 1.4e-49 167.2 0.0 2.2e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CEP07837.1 - 0.00037 20.0 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Glyco_transf_15 PF01793.11 CEP07838.1 - 1e-60 205.4 11.4 1.2e-60 205.1 7.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TSC22 PF01166.13 CEP07839.1 - 3.7e-06 26.8 1.1 5.9e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF1326 PF07040.6 CEP07839.1 - 0.0053 16.5 0.3 0.007 16.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1326) IER PF05760.7 CEP07839.1 - 0.01 15.8 1.1 0.012 15.5 0.8 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF972 PF06156.8 CEP07839.1 - 0.016 15.5 9.7 0.076 13.3 6.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 CEP07839.1 - 0.021 14.2 0.6 0.021 14.2 0.4 2.0 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.13 CEP07839.1 - 0.07 12.8 1.2 0.17 11.6 0.3 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 CEP07839.1 - 0.078 12.8 12.4 0.12 12.2 8.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Rab5-bind PF09311.6 CEP07839.1 - 0.1 12.5 6.7 0.13 12.1 4.7 1.1 1 0 0 1 1 1 0 Rabaptin-like protein DUF2205 PF10224.4 CEP07839.1 - 0.11 12.0 1.7 0.14 11.7 0.4 1.7 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) XRCC4 PF06632.7 CEP07839.1 - 0.15 10.8 4.2 0.19 10.5 2.9 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 bZIP_2 PF07716.10 CEP07839.1 - 0.17 11.7 0.3 0.17 11.7 0.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Pox_A_type_inc PF04508.7 CEP07839.1 - 0.18 11.6 0.4 4.8 7.2 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Baculo_p24 PF05073.7 CEP07839.1 - 0.24 10.9 6.4 0.25 10.8 2.6 1.8 1 1 1 2 2 2 0 Baculovirus P24 capsid protein CENP-H PF05837.7 CEP07839.1 - 0.36 11.0 8.3 0.35 11.0 3.7 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF904 PF06005.7 CEP07839.1 - 0.38 11.0 9.1 2.1 8.7 6.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) HAUS6_N PF14661.1 CEP07839.1 - 0.44 9.8 6.4 0.53 9.5 4.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Presenilin PF01080.12 CEP07839.1 - 0.66 8.7 4.8 0.8 8.4 3.3 1.1 1 0 0 1 1 1 0 Presenilin IncA PF04156.9 CEP07839.1 - 0.91 9.0 4.2 1.3 8.6 2.9 1.2 1 0 0 1 1 1 0 IncA protein Sec2p PF06428.6 CEP07839.1 - 1 9.2 8.3 0.97 9.3 4.7 1.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Microtub_assoc PF07989.6 CEP07839.1 - 1.8 8.4 7.5 4.3 7.2 0.1 2.7 1 1 1 2 2 2 0 Microtubule associated bZIP_1 PF00170.16 CEP07839.1 - 3 7.8 6.1 1.5 8.7 1.3 2.5 2 1 0 2 2 2 0 bZIP transcription factor DivIVA PF05103.8 CEP07839.1 - 3.2 7.8 9.8 4.6 7.3 6.7 1.4 1 1 0 1 1 1 0 DivIVA protein Helitron_like_N PF14214.1 CEP07840.1 - 3.2e-56 189.9 0.0 4.3e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 CEP07840.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) XhlA PF10779.4 CEP07841.1 - 0.038 13.9 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DUF2360 PF10152.4 CEP07841.1 - 0.071 13.4 1.4 0.084 13.1 1.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Spectrin PF00435.16 CEP07841.1 - 0.079 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Spectrin repeat Med3 PF11593.3 CEP07841.1 - 0.14 11.3 3.6 0.17 11.0 2.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1843 PF08898.5 CEP07841.1 - 0.87 9.6 3.9 0.29 11.2 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) SH3_1 PF00018.23 CEP07845.1 - 5.9e-12 44.7 0.0 8.9e-12 44.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP07845.1 - 9.7e-11 41.0 0.0 1.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP07845.1 - 1.2e-10 40.7 0.0 1.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M17 PF00883.16 CEP07846.1 - 2.4e-120 401.0 0.2 3.2e-120 400.7 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CEP07846.1 - 5.4e-14 52.0 0.4 9.9e-14 51.1 0.3 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain ATE_N PF04376.8 CEP07846.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus Mitofilin PF09731.4 CEP07847.1 - 3.1e-82 277.1 41.8 1.7e-69 234.9 25.1 2.1 1 1 0 2 2 2 2 Mitochondrial inner membrane protein Spore_III_AB PF09548.5 CEP07847.1 - 9.8 5.8 13.5 3 7.5 6.5 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) rve PF00665.21 CEP07848.1 - 0.0017 18.4 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF2914 PF11141.3 CEP07848.1 - 0.032 13.7 0.1 0.086 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) BatA PF07584.6 CEP07848.1 - 0.4 10.9 1.5 1.2 9.4 0.2 2.3 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal FAM92 PF06730.6 CEP07849.1 - 0.014 14.7 0.9 0.014 14.7 0.6 3.0 1 1 1 3 3 3 0 FAM92 protein Mt_ATP-synt_D PF05873.7 CEP07849.1 - 0.027 14.1 3.2 0.057 13.0 1.3 2.1 1 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Flu_NS2 PF00601.14 CEP07849.1 - 0.033 14.3 2.0 0.061 13.5 0.4 2.2 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Mating_N PF12731.2 CEP07849.1 - 0.037 13.9 1.5 2.7 7.9 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 Gp-FAR-1 PF05823.7 CEP07849.1 - 0.26 11.2 5.5 0.049 13.5 1.2 1.8 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Phosphorylase PF00343.15 CEP07850.1 - 0 1048.4 0.2 0 1048.2 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase zf-H2C2_2 PF13465.1 CEP07851.1 - 3.7e-12 45.8 12.7 5.9e-08 32.6 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP07851.1 - 2.2e-09 37.0 13.5 2.1e-05 24.5 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP07851.1 - 2.4e-07 30.6 12.5 0.0004 20.5 1.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP07851.1 - 0.00012 22.0 0.9 0.00012 22.0 0.6 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP07851.1 - 0.0014 18.7 2.2 0.0048 17.0 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CEP07851.1 - 0.0022 18.1 1.6 0.0022 18.1 1.1 3.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-BED PF02892.10 CEP07851.1 - 0.026 14.2 4.3 3.2 7.6 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 CEP07851.1 - 0.027 14.3 3.3 0.56 10.2 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.2 CEP07852.1 - 7.2e-05 22.4 0.2 0.00017 21.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP07852.1 - 0.011 15.3 0.5 0.031 13.9 0.4 1.8 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 CEP07852.1 - 0.046 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Hemerythrin PF01814.18 CEP07853.1 - 0.00013 22.1 3.1 0.0047 17.0 0.2 3.1 2 1 0 3 3 3 1 Hemerythrin HHE cation binding domain Tox-REase-2 PF15646.1 CEP07853.1 - 0.0046 16.8 1.1 0.015 15.1 0.7 1.9 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 2 DUF1040 PF06288.8 CEP07853.1 - 0.035 14.3 3.2 0.56 10.4 0.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF1040) DUF4172 PF13776.1 CEP07853.1 - 0.093 12.8 2.1 5.7 7.1 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) Seryl_tRNA_N PF02403.17 CEP07853.1 - 0.19 11.7 31.0 0.092 12.7 0.6 4.9 1 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Nup54 PF13874.1 CEP07853.1 - 0.72 9.5 23.2 0.51 9.9 3.4 3.7 1 1 3 4 4 4 0 Nucleoporin complex subunit 54 MMPL PF03176.10 CEP07853.1 - 1 8.0 6.7 1 8.0 0.3 2.5 1 1 2 3 3 3 0 MMPL family Reo_sigmaC PF04582.7 CEP07853.1 - 8 5.5 16.0 7 5.7 2.3 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein 2OG-FeII_Oxy_2 PF13532.1 CEP07854.1 - 1e-20 74.3 0.0 1.2e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CEP07854.1 - 1.9e-09 37.6 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-U1 PF06220.7 CEP07855.1 - 2e-05 24.0 10.0 0.0022 17.5 7.0 2.3 1 1 0 1 1 1 1 U1 zinc finger DUF2296 PF10058.4 CEP07856.1 - 2.2e-20 72.1 0.5 3.6e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF2663 PF10864.3 CEP07856.1 - 0.014 15.6 2.6 0.031 14.4 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) SMN PF06003.7 CEP07856.1 - 4.9 6.1 12.3 0.033 13.3 1.8 1.9 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) FYDLN_acid PF09538.5 CEP07856.1 - 9.7 6.8 14.4 0.97 10.0 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ctr PF04145.10 CEP07857.1 - 1.4e-19 70.5 0.1 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PIG-P PF08510.7 CEP07857.1 - 0.082 12.5 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 PIG-P FHA PF00498.21 CEP07858.1 - 6.6e-17 61.3 0.5 1.5e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 CEP07858.1 - 3.8e-08 33.0 11.0 6.6e-08 32.2 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP07858.1 - 5e-05 23.3 7.5 0.00014 21.8 5.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEP07858.1 - 0.0018 17.9 7.1 0.003 17.1 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP07858.1 - 0.011 15.4 10.6 0.021 14.4 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP07858.1 - 0.013 15.1 10.3 0.028 14.1 7.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CEP07858.1 - 0.025 14.6 12.8 0.051 13.5 8.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEP07858.1 - 0.21 11.4 4.2 0.49 10.2 2.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 CEP07858.1 - 1.7 8.4 9.1 0.94 9.2 4.8 1.8 2 0 0 2 2 2 0 PHD-finger Ribosomal_L32e PF01655.13 CEP07859.1 - 2.1e-47 159.7 1.0 2.5e-47 159.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 eIF3g PF12353.3 CEP07860.1 - 0.00084 19.2 4.9 0.0018 18.2 3.4 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 CEP07860.1 - 0.043 13.5 0.4 0.12 12.0 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 CEP07860.1 - 0.069 12.8 2.0 0.16 11.6 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 CEP07860.1 - 0.39 10.7 3.5 2.2 8.3 2.4 2.2 1 1 0 1 1 1 0 Zinc knuckle OrfB_Zn_ribbon PF07282.6 CEP07860.1 - 0.45 10.2 2.9 0.5 10.0 1.0 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain V-SNARE_C PF12352.3 CEP07862.1 - 2.5e-13 49.8 1.7 2.5e-13 49.8 1.1 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CEP07862.1 - 1e-06 28.3 0.1 3.1e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Sec20 KxDL PF10241.4 CEP07862.1 - 0.0039 17.0 1.0 0.0039 17.0 0.7 2.8 2 1 1 3 3 3 1 Uncharacterized conserved protein Syntaxin-18_N PF10496.4 CEP07862.1 - 0.022 14.5 1.2 0.056 13.2 0.7 1.9 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Tox-MPTase2 PF15638.1 CEP07862.1 - 0.088 12.3 0.7 0.15 11.5 0.2 1.6 1 1 0 1 1 1 0 Metallopeptidase toxin 2 PTRF_SDPR PF15237.1 CEP07862.1 - 0.2 11.0 5.0 0.65 9.3 0.7 2.1 2 0 0 2 2 2 0 PTRF/SDPR family DivIVA PF05103.8 CEP07862.1 - 3.8 7.5 10.0 2.4 8.2 3.3 2.1 2 0 0 2 2 2 0 DivIVA protein RabGAP-TBC PF00566.13 CEP07863.1 - 5.7e-47 159.9 0.5 5.7e-47 159.9 0.3 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.15 CEP07863.1 - 5.4e-24 83.5 0.7 1.6e-12 46.7 0.1 3.3 3 0 0 3 3 3 2 GRAM domain EF-hand_6 PF13405.1 CEP07863.1 - 0.00095 18.8 0.7 0.22 11.4 0.3 3.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CEP07863.1 - 0.0035 16.5 0.5 0.24 10.7 0.4 3.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CEP07863.1 - 0.03 14.4 0.8 0.03 14.4 0.5 4.1 3 2 0 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.1 CEP07863.1 - 0.044 13.3 5.3 0.47 10.0 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain pair CHDNT PF08073.7 CEP07863.1 - 0.061 13.0 0.1 0.21 11.2 0.1 1.9 1 0 0 1 1 1 0 CHDNT (NUC034) domain CNH PF00780.17 CEP07864.1 - 2.9e-46 158.1 0.0 5.2e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEP07864.1 - 2e-32 112.5 1.6 3e-32 111.9 0.1 2.1 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 CEP07864.1 - 8.5e-23 80.7 0.1 8.5e-23 80.7 0.1 2.6 2 1 1 3 3 3 1 Pleckstrin homology domain DEP PF00610.16 CEP07864.1 - 4.1e-07 29.6 0.0 1.3e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CsbD PF05532.7 CEP07865.1 - 2.8e-11 42.8 1.9 3e-11 42.7 1.3 1.1 1 0 0 1 1 1 1 CsbD-like ANTH PF07651.11 CEP07866.1 - 3.1e-75 252.4 0.0 3.1e-75 252.4 0.0 3.3 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 CEP07866.1 - 1.1e-58 197.4 11.2 1.1e-58 197.4 7.8 4.5 3 1 0 4 4 4 1 I/LWEQ domain ENTH PF01417.15 CEP07866.1 - 7.7e-06 25.7 3.0 8.7e-06 25.6 0.0 2.7 2 1 0 2 2 2 1 ENTH domain Alpha-mann_mid PF09261.6 CEP07866.1 - 6.5 7.0 8.2 4.6 7.5 0.0 3.8 3 0 0 3 3 3 0 Alpha mannosidase, middle domain IATP PF04568.7 CEP07867.1 - 4.2e-08 33.1 2.7 5.2e-08 32.8 1.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP SlyX PF04102.7 CEP07867.1 - 0.017 15.5 0.5 0.32 11.4 0.3 2.1 2 0 0 2 2 2 0 SlyX Bap31 PF05529.7 CEP07867.1 - 0.017 14.5 2.7 0.018 14.5 1.9 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 CEP07867.1 - 0.07 12.0 3.1 0.074 11.9 2.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF802 PF05650.6 CEP07867.1 - 0.078 13.1 0.8 0.13 12.4 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF802) TMF_DNA_bd PF12329.3 CEP07867.1 - 0.11 12.3 7.2 0.48 10.2 4.5 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2188 PF09954.4 CEP07867.1 - 0.14 12.1 0.8 0.22 11.4 0.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) PIF1 PF05970.9 CEP07868.1 - 2.8e-24 85.7 0.1 3.2e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase UPF0160 PF03690.8 CEP07868.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Rad33 PF08730.5 CEP07870.1 - 0.039 13.4 0.5 0.053 12.9 0.3 1.2 1 0 0 1 1 1 0 Rad33 Mito_fiss_Elm1 PF06258.6 CEP07871.1 - 9.7e-20 70.7 0.0 1.4e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial fission ELM1 DXP_reductoisom PF02670.11 CEP07871.1 - 0.18 12.3 0.0 0.88 10.1 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TPP_enzyme_N PF02776.13 CEP07872.1 - 7.7e-52 175.2 0.2 5.8e-50 169.1 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CEP07872.1 - 1.8e-37 128.1 0.0 3.6e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CEP07872.1 - 2.7e-26 91.9 0.1 1.5e-25 89.5 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PNTB PF02233.11 CEP07872.1 - 0.00053 18.8 0.3 0.002 17.0 0.0 2.0 3 0 0 3 3 3 1 NAD(P) transhydrogenase beta subunit Radical_SAM PF04055.16 CEP07872.1 - 0.0062 16.7 0.0 0.046 13.8 0.0 2.3 3 0 0 3 3 3 1 Radical SAM superfamily DXP_synthase_N PF13292.1 CEP07872.1 - 0.011 14.6 0.0 0.029 13.2 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase CO_dh PF02552.11 CEP07872.1 - 0.018 14.5 0.1 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit PH PF00169.24 CEP07873.1 - 5.4e-06 26.5 0.1 5.4e-06 26.5 0.0 3.4 2 1 0 3 3 3 1 PH domain Cofilin_ADF PF00241.15 CEP07873.1 - 5.8e-06 26.2 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mg_trans_NIPA PF05653.9 CEP07874.1 - 1e-96 323.4 22.7 1.2e-96 323.2 15.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CEP07874.1 - 8.8e-07 29.1 4.0 8.8e-07 29.1 2.7 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CEP07874.1 - 6.6e-06 26.1 6.5 6.6e-06 26.1 4.5 3.8 3 1 1 4 4 4 1 EamA-like transporter family YscJ_FliF_C PF08345.6 CEP07874.1 - 0.13 12.1 1.0 0.2 11.5 0.7 1.2 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal EB PF01683.13 CEP07875.1 - 0.44 10.6 7.2 0.96 9.5 5.0 1.5 1 0 0 1 1 1 0 EB module Inositol_P PF00459.20 CEP07877.1 - 2.7e-73 246.5 0.1 3.1e-73 246.4 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Trs65 PF12735.2 CEP07878.1 - 0.31 10.3 4.3 0.39 9.9 2.9 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 SR-25 PF10500.4 CEP07879.1 - 5.7 6.3 8.3 6.8 6.1 5.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3474 PF11960.3 CEP07880.1 - 0.52 10.3 2.8 0.65 10.0 1.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) MAT1 PF06391.8 CEP07880.1 - 0.59 9.6 5.9 0.75 9.3 4.1 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Rtf2 PF04641.7 CEP07880.1 - 6.5 5.8 8.4 7.7 5.6 5.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RRM_6 PF14259.1 CEP07881.1 - 4.3e-08 33.0 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP07881.1 - 0.00037 20.0 0.0 0.00067 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP07881.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP07881.1 - 0.2 11.5 0.1 0.2 11.5 0.0 2.2 2 1 0 2 2 2 0 RNA binding motif SPT16 PF08644.6 CEP07881.1 - 4.5 7.1 9.5 1.6 8.5 4.5 1.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Beach PF02138.13 CEP07883.1 - 2e-110 368.5 0.0 5.6e-110 367.0 0.0 1.9 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CEP07883.1 - 1.3e-11 44.2 0.0 4.1e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FYVE PF01363.16 CEP07883.1 - 8.8e-11 41.5 15.9 1.8e-10 40.5 11.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.27 CEP07883.1 - 6.8e-07 28.9 5.6 0.062 13.2 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 CEP07883.1 - 8.3e-07 29.3 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Aminotran_1_2 PF00155.16 CEP07884.1 - 1.5e-28 99.8 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CEP07884.1 - 0.00069 18.0 0.0 0.006 14.9 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CEP07884.1 - 0.011 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cyclin_N PF00134.18 CEP07885.1 - 2.3e-11 43.3 0.1 3.3e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CEP07885.1 - 5.7e-11 43.0 0.1 6.8e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin OPT PF03169.10 CEP07886.1 - 3.8e-177 590.5 44.9 4.3e-177 590.3 31.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DEAD PF00270.24 CEP07887.1 - 3.3e-45 153.6 0.0 2.5e-44 150.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP07887.1 - 3.4e-25 87.7 0.0 8.3e-25 86.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CEP07887.1 - 0.031 14.0 3.0 0.17 11.6 0.1 3.3 3 1 1 4 4 4 0 Part of AAA domain ATP-synt_G PF04718.10 CEP07888.1 - 6.6e-22 78.1 0.6 1e-21 77.4 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Peptidase_A22B PF04258.8 CEP07888.1 - 0.017 14.5 0.1 0.02 14.3 0.1 1.0 1 0 0 1 1 1 0 Signal peptide peptidase DUF892 PF05974.7 CEP07889.1 - 0.0053 16.5 0.7 0.0066 16.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF892) DegS PF05384.6 CEP07889.1 - 0.016 14.4 1.9 0.019 14.2 1.3 1.1 1 0 0 1 1 1 0 Sensor protein DegS DUF948 PF06103.6 CEP07889.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.8 CEP07889.1 - 0.02 14.6 2.9 0.028 14.1 2.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4047 PF13256.1 CEP07889.1 - 0.02 14.8 2.2 0.024 14.6 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) HALZ PF02183.13 CEP07889.1 - 0.021 14.5 0.5 0.033 13.8 0.3 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper AKNA PF12443.3 CEP07889.1 - 0.035 14.1 0.5 0.042 13.8 0.3 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor THOC7 PF05615.8 CEP07889.1 - 0.057 13.6 1.5 0.067 13.4 1.0 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 DUF3490 PF11995.3 CEP07889.1 - 0.089 12.3 0.2 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Kinetocho_Slk19 PF12709.2 CEP07889.1 - 0.11 12.5 2.5 0.14 12.2 1.7 1.2 1 0 0 1 1 1 0 Central kinetochore-associated Bap31 PF05529.7 CEP07889.1 - 0.13 11.7 1.5 0.16 11.4 1.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Integrase_DNA PF02920.10 CEP07889.1 - 0.13 11.6 1.1 0.17 11.2 0.7 1.1 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase DUF4200 PF13863.1 CEP07889.1 - 0.16 11.8 5.6 0.22 11.4 3.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) APG6 PF04111.7 CEP07889.1 - 0.24 10.4 2.2 0.26 10.3 1.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CEP07889.1 - 0.29 10.6 4.8 0.61 9.6 2.6 1.7 1 1 0 1 1 1 0 Septum formation initiator Pox_A_type_inc PF04508.7 CEP07889.1 - 0.59 10.0 2.7 7.1 6.6 0.5 2.5 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Innate_immun PF12782.2 CEP07890.1 - 0.37 9.9 12.0 0.65 9.1 8.3 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Rhomboid PF01694.17 CEP07892.1 - 1.6e-06 28.1 5.9 2.3e-06 27.7 4.1 1.2 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.11 CEP07892.1 - 0.0039 16.6 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 CEP07892.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain ThiW PF09512.5 CEP07892.1 - 0.43 10.3 6.8 0.64 9.8 0.5 2.3 1 1 2 3 3 3 0 Thiamine-precursor transporter protein (ThiW) COX4 PF02936.9 CEP07893.1 - 5.1e-36 123.5 0.0 5.7e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Prefoldin PF02996.12 CEP07894.1 - 7e-17 61.1 4.0 8.4e-16 57.7 2.7 2.1 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 CEP07894.1 - 9.1e-07 28.5 0.7 1.4e-06 28.0 0.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit WEMBL PF05701.6 CEP07894.1 - 0.0017 16.9 3.6 0.0019 16.7 2.5 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light TMF_TATA_bd PF12325.3 CEP07894.1 - 0.0096 15.6 4.8 0.18 11.5 0.5 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 CEP07894.1 - 0.01 14.5 5.1 0.034 12.8 0.4 1.8 1 1 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.1 CEP07894.1 - 0.017 14.2 4.6 0.022 13.9 3.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 CEP07894.1 - 0.021 14.6 2.8 0.35 10.6 2.0 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CEP07894.1 - 0.029 14.6 5.4 2.2 8.5 0.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 CEP07894.1 - 0.035 13.9 2.9 3.7 7.4 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.8 CEP07894.1 - 0.052 13.9 0.3 8.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Prefoldin_2 PF01920.15 CEP07894.1 - 0.055 13.2 7.4 0.46 10.2 0.6 2.3 1 1 0 2 2 2 0 Prefoldin subunit IncA PF04156.9 CEP07894.1 - 0.058 12.9 1.7 0.11 12.1 1.2 1.6 1 1 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 CEP07894.1 - 0.12 13.0 2.6 0.49 11.1 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain HCR PF07111.7 CEP07894.1 - 0.17 9.8 2.8 0.08 10.9 0.5 1.4 2 0 0 2 2 2 0 Alpha helical coiled-coil rod protein (HCR) DUF2164 PF09932.4 CEP07894.1 - 0.19 11.5 2.5 0.34 10.7 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2164) Sec2p PF06428.6 CEP07894.1 - 0.77 9.6 7.3 0.95 9.3 0.2 2.4 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p SYCE1 PF15233.1 CEP07894.1 - 1.6 8.6 6.2 1.7 8.5 1.0 2.1 1 1 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF1664 PF07889.7 CEP07894.1 - 2.2 8.0 6.4 7.9 6.3 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 CEP07894.1 - 5 7.5 8.3 10 6.4 1.3 2.8 2 2 1 3 3 3 0 Snapin/Pallidin Fib_alpha PF08702.5 CEP07894.1 - 5.2 7.1 7.8 2 8.5 1.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FH2 PF02181.18 CEP07895.1 - 2.6e-81 273.3 2.0 2.6e-81 273.3 1.4 2.7 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.8 CEP07895.1 - 3.1e-46 157.1 0.0 1.2e-45 155.1 0.0 2.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CEP07895.1 - 2.8e-39 134.5 0.2 2.8e-39 134.5 0.1 3.3 2 1 1 3 3 3 1 Diaphanous FH3 Domain Sec16_C PF12931.2 CEP07896.1 - 9.4e-37 127.2 0.2 1.7e-36 126.4 0.1 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 SWIRM PF04433.12 CEP07897.1 - 3.8e-32 110.2 0.1 9.3e-32 109.0 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CEP07897.1 - 2.3e-11 43.5 0.1 1.1e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP07897.1 - 1.8e-08 34.3 0.2 6.9e-08 32.4 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 CEP07897.1 - 5.8e-07 28.9 4.0 1.1e-06 28.0 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Zn_ribbon_2 PF12674.2 CEP07897.1 - 0.009 16.3 0.8 0.03 14.6 0.6 2.0 1 0 0 1 1 1 1 Putative zinc ribbon domain Chordopox_RPO7 PF05864.7 CEP07897.1 - 0.083 12.9 0.4 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF3787 PF12655.2 CEP07897.1 - 0.24 11.1 3.8 2.5 7.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3787) Lzipper-MIP1 PF14389.1 CEP07897.1 - 1.9 8.6 8.7 5.5 7.1 3.4 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Nol1_Nop2_Fmu PF01189.12 CEP07899.1 - 3e-33 115.4 0.0 3e-29 102.3 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family TraF PF13728.1 CEP07899.1 - 0.028 13.8 1.3 0.11 12.0 0.6 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein FHA PF00498.21 CEP07900.1 - 8.3e-13 48.2 0.1 8.3e-13 48.2 0.1 2.1 3 0 0 3 3 3 1 FHA domain PRCC PF10253.4 CEP07901.1 - 4.4e-17 63.3 5.8 4.4e-17 63.3 4.0 2.5 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting WD40 PF00400.27 CEP07902.1 - 1.2e-20 72.5 7.1 1.5e-05 24.6 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 CEP07902.1 - 0.0013 16.9 0.0 0.046 11.8 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Sex_peptide PF08138.6 CEP07903.1 - 0.033 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Sex peptide (SP) family DDE_3 PF13358.1 CEP07904.1 - 1e-31 109.6 0.1 1.6e-31 109.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP07904.1 - 0.0001 23.0 0.0 0.0025 18.5 0.0 3.0 4 0 0 4 4 4 1 Homeodomain-like domain DDE_1 PF03184.14 CEP07904.1 - 0.00012 21.3 0.2 0.00034 19.8 0.1 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP07904.1 - 0.00033 20.7 0.0 0.0007 19.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP07904.1 - 0.04 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 CEP07904.1 - 0.076 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain U3_snoRNA_assoc PF08297.6 CEP07904.1 - 0.52 10.5 5.6 1 9.6 2.5 2.3 2 0 0 2 2 2 0 U3 snoRNA associated F-box-like PF12937.2 CEP07906.1 - 3.9e-10 39.3 0.2 7e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like FTH PF01827.22 CEP07906.1 - 0.024 14.2 1.1 0.1 12.2 0.1 2.1 2 0 0 2 2 2 0 FTH domain F-box PF00646.28 CEP07906.1 - 0.11 12.2 1.5 0.25 11.0 0.3 2.2 2 1 0 2 2 2 0 F-box domain GST_N_3 PF13417.1 CEP07907.1 - 2.4e-18 66.1 0.0 4.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP07907.1 - 2.9e-15 56.1 0.0 6e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP07907.1 - 8.1e-14 51.3 0.0 1.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEP07907.1 - 1.6e-07 31.0 0.0 2.5e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP07907.1 - 3.5e-06 26.9 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP07907.1 - 0.00039 20.8 0.0 0.00057 20.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 CEP07907.1 - 0.00052 20.2 0.0 0.041 14.1 0.0 2.3 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein Dynactin_p22 PF07426.6 CEP07907.1 - 0.015 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 tRNA-synt_2c PF01411.14 CEP07908.1 - 2.2e-162 541.2 0.0 2.9e-162 540.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CEP07908.1 - 4.1e-14 52.1 0.1 9.6e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CEP07908.1 - 0.00069 19.2 0.1 0.0021 17.7 0.1 1.9 1 0 0 1 1 1 1 DHHA1 domain Ribosomal_L23eN PF03939.8 CEP07909.1 - 4.2e-19 68.3 5.8 9.3e-19 67.2 4.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 CEP07909.1 - 6.1e-19 67.7 2.0 6.1e-19 67.7 1.4 2.0 2 1 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.6 CEP07909.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DUF1323 PF07037.6 CEP07909.1 - 0.092 12.9 0.2 0.25 11.5 0.1 1.7 1 1 1 2 2 2 0 Putative transcription regulator (DUF1323) Tubulin PF00091.20 CEP07909.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Oxysterol_BP PF01237.13 CEP07910.1 - 3.7e-108 361.1 1.2 3.7e-108 361.1 0.9 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 CEP07910.1 - 1.2e-20 73.4 0.5 3.3e-20 71.9 0.4 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain GOLD_2 PF13897.1 CEP07910.1 - 2.3e-07 31.1 1.6 0.00012 22.2 1.1 2.8 1 1 0 1 1 1 1 Golgi-dynamics membrane-trafficking PH PF00169.24 CEP07910.1 - 5e-05 23.4 0.4 0.00029 20.9 0.1 2.5 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 CEP07910.1 - 0.00012 22.2 10.1 0.0002 21.6 4.0 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain EMP24_GP25L PF01105.19 CEP07910.1 - 0.014 15.1 0.3 0.014 15.1 0.2 2.7 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD EF-hand_1 PF00036.27 CEP07911.1 - 6.8e-24 81.3 5.2 2e-05 23.5 0.0 5.9 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CEP07911.1 - 5.4e-22 75.6 3.2 3e-05 23.5 0.0 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 CEP07911.1 - 4.5e-20 71.5 6.5 7e-09 35.6 2.0 3.5 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CEP07911.1 - 2.3e-19 67.7 2.1 2.8e-05 23.2 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CEP07911.1 - 1e-14 53.8 3.2 1.8e-08 33.8 0.0 4.6 4 2 1 5 5 5 4 EF-hand domain pair Toprim_2 PF13155.1 CEP07911.1 - 0.0016 18.6 2.0 1.2 9.5 0.6 3.1 1 1 1 2 2 2 2 Toprim-like EF-hand_9 PF14658.1 CEP07911.1 - 0.049 13.5 0.1 1.4 8.8 0.0 2.9 3 1 0 3 3 3 0 EF-hand domain GUN4 PF05419.7 CEP07911.1 - 3.9 7.2 9.8 0.5 10.1 0.0 3.1 2 1 0 2 2 2 0 GUN4-like Pex14_N PF04695.8 CEP07911.1 - 4.2 7.4 7.9 7.1 6.6 5.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NUDIX PF00293.23 CEP07912.1 - 7.4e-16 58.0 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ank_4 PF13637.1 CEP07912.1 - 6.6e-13 48.7 0.1 7.2e-08 32.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEP07912.1 - 2.7e-11 43.6 0.0 7.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEP07912.1 - 6.8e-09 35.0 0.0 5.5e-06 25.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat zf-NADH-PPase PF09297.6 CEP07912.1 - 5.8e-07 28.9 2.0 1.2e-06 27.9 1.4 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_5 PF13857.1 CEP07912.1 - 1.1e-06 28.6 0.0 3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP07912.1 - 9.5e-06 25.3 0.0 6.4e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat NUDIX-like PF09296.6 CEP07912.1 - 0.0031 17.8 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain DZR PF12773.2 CEP07912.1 - 0.15 11.9 1.0 0.26 11.1 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF3535 PF12054.3 CEP07914.1 - 2e-104 349.6 0.6 5.7e-102 341.6 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CEP07914.1 - 8.3e-72 241.4 0.0 1.3e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 CEP07914.1 - 7.5e-14 50.5 12.4 0.3 11.2 0.2 10.0 10 0 0 10 10 10 3 HEAT repeat Helicase_C PF00271.26 CEP07914.1 - 1.1e-12 47.6 0.0 8.2e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 CEP07914.1 - 0.00036 20.9 12.3 5.5 7.6 0.1 7.6 8 1 0 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.1 CEP07914.1 - 0.00057 20.1 7.1 0.0045 17.2 0.1 4.8 4 2 1 5 5 5 1 HEAT repeats DUF1546 PF07571.8 CEP07914.1 - 0.0022 18.0 2.1 9.7 6.3 0.0 5.2 6 0 0 6 6 6 1 Protein of unknown function (DUF1546) Vac14_Fab1_bd PF12755.2 CEP07914.1 - 0.0025 18.1 0.0 4.5 7.7 0.0 3.5 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region zf-C3HC4_2 PF13923.1 CEP07915.1 - 3.4e-07 30.1 9.7 1e-06 28.6 6.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP07915.1 - 4.6e-06 26.1 15.4 1e-05 25.1 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP07915.1 - 1.7e-05 24.5 11.5 1.7e-05 24.5 8.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 CEP07915.1 - 8.7e-05 22.3 8.5 0.00037 20.3 5.9 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CEP07915.1 - 0.00015 21.4 14.2 0.0003 20.4 9.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP07915.1 - 0.00025 20.6 10.8 0.00045 19.8 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP07915.1 - 0.0038 16.9 7.8 0.0094 15.6 5.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CEP07915.1 - 0.0099 15.6 6.2 0.034 13.9 4.3 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DZR PF12773.2 CEP07915.1 - 0.054 13.3 7.1 0.55 10.0 1.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon RabGAP-TBC PF00566.13 CEP07916.1 - 9.3e-31 106.9 2.0 9.3e-31 106.9 1.4 2.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain ABC2_membrane_2 PF12679.2 CEP07916.1 - 0.044 12.6 0.2 7.2 5.3 0.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein tRNA_anti-codon PF01336.20 CEP07916.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain GRP PF07172.6 CEP07916.1 - 3.8 8.0 14.1 8.6 6.9 9.8 1.6 1 0 0 1 1 1 0 Glycine rich protein family SCP2 PF02036.12 CEP07917.1 - 1.3e-23 83.2 0.8 1.5e-23 82.9 0.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CEP07917.1 - 0.00062 19.7 0.2 0.00089 19.2 0.1 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Isochorismatase PF00857.15 CEP07919.1 - 3e-26 92.3 0.0 4.8e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Allantoicase PF03561.10 CEP07920.1 - 1.2e-36 125.4 0.0 6.4e-18 64.6 0.0 2.5 2 1 0 2 2 2 2 Allantoicase repeat TRAPP PF04051.11 CEP07921.1 - 8.5e-43 145.4 0.0 1e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SUI1 PF01253.17 CEP07922.1 - 1.3e-13 50.5 0.9 7.1e-13 48.1 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor SUI1 SWIB PF02201.13 CEP07922.1 - 0.00053 19.6 0.3 0.0013 18.3 0.2 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Kin17_mid PF10357.4 CEP07922.1 - 0.00091 18.8 0.0 0.0032 17.1 0.0 1.9 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein PUA PF01472.15 CEP07922.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 PUA domain Abhydrolase_3 PF07859.8 CEP07923.1 - 3.6e-18 65.9 0.0 7.2e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 CEP07923.1 - 1.7e-17 63.3 1.8 2.6e-16 59.4 1.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CEP07923.1 - 1.4e-15 57.2 0.0 2.7e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP07923.1 - 1.7e-11 43.8 0.1 4.7e-05 22.7 0.0 2.9 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CEP07923.1 - 3.7e-08 33.5 0.0 4.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 CEP07923.1 - 3.2e-06 26.2 0.1 5.1e-06 25.6 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.2 CEP07923.1 - 9.2e-06 24.7 0.0 1.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF3089 PF11288.3 CEP07923.1 - 0.0039 16.3 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3089) Chlorophyllase PF07224.6 CEP07923.1 - 0.0064 15.3 0.1 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase DUF2305 PF10230.4 CEP07923.1 - 0.0069 15.8 0.2 0.024 14.0 0.1 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF2235 PF09994.4 CEP07923.1 - 0.03 13.6 0.0 0.26 10.5 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2424 PF10340.4 CEP07923.1 - 0.067 11.8 0.1 0.098 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) PAF-AH_p_II PF03403.8 CEP07923.1 - 0.12 10.6 0.3 1.1 7.4 0.0 2.2 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Ser_hydrolase PF06821.8 CEP07923.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase SAP PF02037.22 CEP07924.1 - 0.00052 19.4 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF1932 PF09130.6 CEP07925.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Thr_synth_N PF14821.1 CEP07926.1 - 7.7e-29 99.5 0.0 1.6e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 CEP07926.1 - 9.2e-20 71.0 0.0 1.4e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NUP50 PF08911.6 CEP07926.1 - 0.044 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) DUF421 PF04239.7 CEP07926.1 - 0.15 11.5 0.0 18 4.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF421) Arm PF00514.18 CEP07927.1 - 3.7e-07 29.7 3.0 2.8e-05 23.7 0.1 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CEP07927.1 - 2.2e-06 27.9 1.4 0.46 11.0 0.0 5.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 CEP07927.1 - 0.0026 17.6 0.5 0.65 10.2 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat Vac14_Fab1_bd PF12755.2 CEP07927.1 - 0.014 15.7 0.0 12 6.3 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region MFS_1 PF07690.11 CEP07928.1 - 5e-13 48.5 27.2 5e-13 48.5 18.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 CEP07928.1 - 5.4e-12 45.4 2.9 5.4e-12 45.4 2.0 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Actin PF00022.14 CEP07929.1 - 1.8e-93 313.0 0.0 2.3e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CEP07929.1 - 2.8e-05 22.8 0.0 0.1 11.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Robl_LC7 PF03259.12 CEP07929.1 - 0.097 12.2 0.1 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Roadblock/LC7 domain Nitr_red_assoc PF09655.5 CEP07930.1 - 0.026 14.8 3.8 0.06 13.6 2.7 1.5 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Senescence_reg PF04520.8 CEP07930.1 - 0.77 10.2 9.0 43 4.5 6.2 3.0 1 1 0 1 1 1 0 Senescence regulator Ras PF00071.17 CEP07931.1 - 1.5e-58 196.7 0.1 1.8e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP07931.1 - 1.6e-21 76.9 0.0 2.8e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP07931.1 - 8.7e-08 31.5 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP07931.1 - 9.5e-05 21.9 0.1 0.0003 20.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP07931.1 - 0.00048 20.0 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 CEP07931.1 - 0.024 14.0 0.5 0.45 9.9 0.1 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 CEP07931.1 - 0.08 12.1 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 CEP07931.1 - 0.08 12.2 0.0 0.42 9.8 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 CEP07931.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CEP07931.1 - 0.11 12.5 0.1 1.4 9.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain Ribosomal_S7e PF01251.13 CEP07932.1 - 1.8e-79 265.6 0.7 2e-79 265.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e IF4E PF01652.13 CEP07933.1 - 4.7e-55 185.6 1.6 5.6e-55 185.3 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DSS1_SEM1 PF05160.8 CEP07933.1 - 0.33 10.7 2.8 0.38 10.5 0.0 2.4 3 1 0 3 3 3 0 DSS1/SEM1 family Ribosomal_S6e PF01092.14 CEP07934.1 - 3e-60 201.4 0.3 6e-60 200.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 CEP07934.1 - 0.061 13.3 0.3 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic region Integrase_AP2 PF14657.1 CEP07934.1 - 9.5 6.0 7.7 16 5.3 0.3 3.5 3 0 0 3 3 3 0 AP2-like DNA-binding integrase domain DUF3414 PF11894.3 CEP07935.1 - 1.5e-208 695.1 33.3 2e-208 694.7 23.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF2246 PF10229.4 CEP07936.1 - 5.2e-17 62.0 0.0 6.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) GRAM PF02893.15 CEP07937.1 - 1e-17 63.3 0.0 3e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 GRAM domain GPI-anchored PF10342.4 CEP07938.1 - 0.77 10.2 5.6 0.43 11.1 0.1 2.4 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PA26 PF04636.8 CEP07939.1 - 9.2e-78 261.9 0.0 1.4e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF4286 PF14114.1 CEP07940.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Toxin_R_bind_C PF07951.7 CEP07942.1 - 0.1 12.2 7.1 0.036 13.7 1.2 2.2 2 0 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding CTP_transf_2 PF01467.21 CEP07943.1 - 2.4e-31 108.9 0.0 3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase UQ_con PF00179.21 CEP07944.1 - 1.9e-17 62.9 0.0 2.1e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CEP07944.1 - 0.0031 17.3 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain Sld5 PF05916.6 CEP07945.1 - 2.1e-06 27.9 0.1 3.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein Tim17 PF02466.14 CEP07946.1 - 5.2e-14 52.3 13.9 6.7e-14 52.0 9.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SF3b1 PF08920.5 CEP07947.1 - 5.4e-40 136.7 2.0 5.4e-40 136.7 1.4 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CEP07947.1 - 1.4e-14 54.1 5.7 0.0057 16.9 0.0 7.7 5 3 2 8 8 8 4 HEAT repeats HEAT PF02985.17 CEP07947.1 - 8.4e-13 47.2 5.8 0.26 11.4 0.0 9.5 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 CEP07947.1 - 4.8e-10 39.6 3.1 0.86 10.1 0.1 8.2 6 3 4 10 10 10 3 HEAT-like repeat Adaptin_N PF01602.15 CEP07947.1 - 3.8e-05 22.2 3.0 0.027 12.8 0.1 3.1 2 1 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CEP07947.1 - 0.0001 22.6 4.5 0.75 10.2 0.0 4.5 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Dopey_N PF04118.9 CEP07947.1 - 0.005 15.6 1.2 0.67 8.6 0.0 3.6 3 1 0 3 3 3 1 Dopey, N-terminal Arm PF00514.18 CEP07947.1 - 0.02 14.7 6.0 9.1 6.2 0.0 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DNA_binding_1 PF01035.15 CEP07947.1 - 0.043 13.5 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain NodA PF02474.10 CEP07947.1 - 0.079 12.2 0.4 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein A (NodA) Pribosyl_synth PF14572.1 CEP07948.1 - 5.9e-40 136.9 1.3 6.4e-34 117.2 0.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CEP07948.1 - 9.3e-37 125.3 0.1 1.3e-34 118.4 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CEP07948.1 - 2.4e-12 46.6 0.1 5.1e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CEP07948.1 - 0.0079 15.4 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AA_permease_2 PF13520.1 CEP07950.1 - 4e-06 25.6 4.1 4.5e-06 25.4 2.9 1.1 1 0 0 1 1 1 1 Amino acid permease Homeobox PF00046.24 CEP07951.1 - 4.8e-19 67.7 3.0 7e-19 67.1 1.3 1.9 2 0 0 2 2 2 1 Homeobox domain Ribosomal_60s PF00428.14 CEP07951.1 - 0.024 15.0 6.4 0.26 11.7 1.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 CEP07951.1 - 0.63 10.6 9.9 0.21 12.1 4.3 2.1 2 0 0 2 2 2 0 Chorion family 2 PH PF00169.24 CEP07952.1 - 7.8e-07 29.2 0.1 7.8e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 PH domain PIN_4 PF13638.1 CEP07953.1 - 2.4e-27 95.6 0.1 5.5e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 PIN domain Ank_2 PF12796.2 CEP07954.1 - 6.5e-42 141.7 5.7 5e-18 65.2 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEP07954.1 - 2.1e-39 131.4 7.6 3.5e-08 32.8 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat zf-DHHC PF01529.15 CEP07954.1 - 3.7e-37 127.3 7.2 3.7e-37 127.3 5.0 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 CEP07954.1 - 4.7e-31 106.5 3.5 6.8e-09 36.0 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP07954.1 - 3.5e-28 96.9 7.4 9.6e-08 32.0 0.0 5.8 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP07954.1 - 1.2e-24 83.9 1.1 0.003 17.6 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat TFIIA PF03153.8 CEP07955.1 - 0.0015 18.5 0.5 0.0019 18.1 0.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RHD3 PF05879.7 CEP07956.1 - 6.3e-244 811.3 8.6 1.2e-208 694.6 3.5 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 CEP07956.1 - 5.3e-06 25.6 0.2 1.3e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 CEP07956.1 - 5.6e-06 26.2 0.3 1.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CEP07956.1 - 0.00017 21.5 0.0 0.0006 19.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CEP07956.1 - 0.0012 19.3 0.0 0.0035 17.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CEP07956.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain HEAT PF02985.17 CEP07957.1 - 1.6e-05 24.5 1.5 0.15 12.2 0.0 3.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 CEP07957.1 - 7.4e-05 22.9 0.8 0.0014 18.8 0.2 2.8 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.2 CEP07957.1 - 0.0014 18.5 0.0 0.0052 16.6 0.0 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CEP07957.1 - 0.0016 18.8 5.6 0.024 15.1 0.5 4.6 4 1 1 5 5 5 1 HEAT-like repeat Arm PF00514.18 CEP07957.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 3.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat SEN1_N PF12726.2 CEP07957.1 - 0.0046 15.0 0.9 0.067 11.2 0.2 2.4 3 0 0 3 3 3 1 SEN1 N terminal ADP_ribosyl_GH PF03747.9 CEP07957.1 - 0.07 12.8 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Ric8 PF10165.4 CEP07957.1 - 0.22 10.2 2.9 0.41 9.4 0.2 2.5 2 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn MFS_1 PF07690.11 CEP07958.1 - 1.3e-13 50.4 31.2 1.7e-13 50.0 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 CEP07958.1 - 2.5e-12 46.5 1.8 2.5e-12 46.5 1.2 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 SWIRM PF04433.12 CEP07959.1 - 1e-09 38.3 0.0 2.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain HYLS1_C PF15311.1 CEP07959.1 - 0.84 9.9 5.4 0.2 11.9 0.8 2.0 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus WD40 PF00400.27 CEP07960.1 - 8.5e-22 76.1 5.9 3e-06 26.9 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat PD40 PF07676.7 CEP07960.1 - 0.0089 15.6 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 CEP07960.1 - 0.061 13.0 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PAS_3 PF08447.6 CEP07961.1 - 1e-14 54.3 0.0 2.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold GATA PF00320.22 CEP07961.1 - 1.4e-14 53.1 7.1 2.5e-14 52.3 4.9 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 CEP07961.1 - 5.4e-10 39.0 0.0 1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 CEP07961.1 - 2.7e-08 34.1 0.0 6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 CEP07961.1 - 3e-08 33.6 0.0 5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 CEP07961.1 - 6.7e-07 29.2 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 PAS domain COX7a PF02238.10 CEP07962.1 - 0.012 15.2 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa WRKY PF03106.10 CEP07963.1 - 3.4e-06 26.7 3.8 7.3e-06 25.7 2.6 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Svf1 PF08622.5 CEP07964.1 - 4.7e-87 292.0 3.9 5.5e-87 291.7 2.7 1.0 1 0 0 1 1 1 1 Svf1-like PHD PF00628.24 CEP07966.1 - 1.5e-07 30.9 14.5 3.7e-07 29.7 9.3 2.3 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CEP07966.1 - 0.021 14.1 9.2 0.042 13.1 6.4 1.6 1 0 0 1 1 1 0 PHD-finger DUF4611 PF15387.1 CEP07966.1 - 0.078 13.1 4.7 1.2 9.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HEAT PF02985.17 CEP07968.1 - 2.2e-15 55.2 10.2 0.0029 17.5 0.1 8.3 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 CEP07968.1 - 6.5e-10 39.1 2.5 1.3e-05 25.3 0.0 5.8 5 2 2 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 CEP07968.1 - 0.002 18.5 2.9 0.69 10.4 0.1 4.5 3 1 0 3 3 3 1 HEAT-like repeat Not3 PF04065.10 CEP07969.1 - 5.7e-94 313.7 28.9 1e-93 312.8 20.0 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CEP07969.1 - 7.9e-45 152.0 11.4 3.3e-44 150.0 7.9 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family VTC PF09359.5 CEP07970.1 - 1.4e-85 286.7 0.1 2.1e-85 286.1 0.1 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEP07970.1 - 3.3e-24 86.1 4.9 2.2e-11 44.0 0.1 3.5 1 1 1 2 2 2 2 SPX domain Sda PF08970.5 CEP07970.1 - 0.028 13.9 0.2 1.5 8.3 0.3 3.2 3 0 0 3 3 3 0 Sporulation inhibitor A VTC PF09359.5 CEP07971.1 - 1.4e-38 132.5 0.0 3.8e-38 131.1 0.0 1.8 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 CEP07971.1 - 1.5e-12 47.5 4.7 3.5e-12 46.3 3.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) N6_N4_Mtase PF01555.13 CEP07971.1 - 1.3e-09 37.9 0.6 0.00043 19.8 0.0 3.3 3 0 0 3 3 3 2 DNA methylase Methyltransf_26 PF13659.1 CEP07971.1 - 3.5e-06 27.0 0.0 1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain GATA PF00320.22 CEP07971.1 - 0.0091 15.3 0.7 0.0091 15.3 0.5 3.5 4 0 0 4 4 4 1 GATA zinc finger DNA_pol_B_thumb PF14791.1 CEP07972.1 - 7.9e-17 60.7 0.0 1.6e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 CEP07972.1 - 3.9e-15 55.1 0.2 2.4e-13 49.3 0.0 2.6 2 1 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 CEP07972.1 - 3.1e-13 49.7 0.3 8e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 CEP07972.1 - 0.00015 21.7 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH PF00633.18 CEP07972.1 - 0.06 13.0 0.0 0.37 10.5 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.1 CEP07972.1 - 0.066 13.4 0.1 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain RVT_1 PF00078.22 CEP07973.1 - 4.6e-05 22.8 0.6 0.026 13.9 0.1 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Wzz PF02706.10 CEP07973.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Chain length determinant protein ABC_tran PF00005.22 CEP07974.1 - 1.2e-48 164.8 0.0 4.7e-25 88.4 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CEP07974.1 - 1.4e-19 71.1 3.2 2.7e-05 24.2 0.0 4.6 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 CEP07974.1 - 4.3e-13 49.0 4.5 0.015 14.5 0.0 4.6 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CEP07974.1 - 4.5e-09 35.7 0.2 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CEP07974.1 - 1.1e-07 31.2 0.0 0.014 14.6 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 CEP07974.1 - 2e-07 30.9 0.1 0.063 13.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CEP07974.1 - 2.3e-07 30.7 1.0 0.081 12.8 0.0 4.2 5 0 0 5 5 3 2 50S ribosome-binding GTPase Chromo PF00385.19 CEP07974.1 - 9.2e-07 28.4 0.2 2.2e-06 27.2 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.1 CEP07974.1 - 9.2e-07 28.2 0.3 0.13 11.2 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 CEP07974.1 - 2.4e-06 28.3 0.4 0.045 14.5 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CEP07974.1 - 5.7e-06 26.8 8.2 0.017 15.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 CEP07974.1 - 1.5e-05 24.8 0.0 0.032 14.0 0.0 3.4 4 0 0 4 4 2 1 Dynamin family SbcCD_C PF13558.1 CEP07974.1 - 1.9e-05 24.5 0.1 0.039 13.8 0.0 3.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CEP07974.1 - 2.4e-05 24.4 0.3 0.15 12.1 0.1 3.7 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 CEP07974.1 - 3e-05 24.5 0.0 0.083 13.3 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 CEP07974.1 - 3.2e-05 23.1 0.1 0.39 9.7 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_10 PF12846.2 CEP07974.1 - 0.00022 20.7 0.3 1 8.7 0.1 3.1 3 0 0 3 3 3 2 AAA-like domain AAA_28 PF13521.1 CEP07974.1 - 0.00031 20.7 0.0 0.06 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CEP07974.1 - 0.00033 19.5 0.2 0.25 10.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 CEP07974.1 - 0.00056 19.9 0.2 0.16 11.9 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 CEP07974.1 - 0.0011 19.1 0.0 3.3 7.9 0.0 3.2 2 0 0 2 2 2 2 RNA helicase CLASP_N PF12348.3 CEP07974.1 - 0.003 16.9 0.1 1.7 7.9 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal MobB PF03205.9 CEP07974.1 - 0.0044 16.7 0.4 0.4 10.3 0.1 3.1 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CEP07974.1 - 0.0057 16.9 1.9 2.1 8.6 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 CEP07974.1 - 0.0058 16.2 2.3 1.1 8.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CEP07974.1 - 0.0069 16.0 0.2 1.5 8.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 CEP07974.1 - 0.011 15.6 3.2 1.2 8.8 0.3 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_25 PF13481.1 CEP07974.1 - 0.012 15.0 0.0 6.1 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 CEP07974.1 - 0.022 13.7 0.1 8.8 5.2 0.0 3.0 3 0 0 3 3 3 0 Septin cobW PF02492.14 CEP07974.1 - 0.026 13.9 1.7 11 5.4 0.0 3.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 CEP07974.1 - 0.032 14.1 0.0 22 4.9 0.0 3.4 2 1 1 3 3 3 0 AAA domain AAA PF00004.24 CEP07974.1 - 0.058 13.5 0.3 7.1 6.8 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CEP07974.1 - 0.062 12.7 0.2 17 4.7 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Vac14_Fab1_bd PF12755.2 CEP07974.1 - 0.099 13.0 0.0 47 4.4 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region PGAP1 PF07819.8 CEP07975.1 - 1.4e-73 247.2 0.1 2e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CEP07975.1 - 5.5e-06 25.8 0.1 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CEP07975.1 - 5.7e-05 23.1 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP07975.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 CEP07975.1 - 0.00071 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 CEP07975.1 - 0.00071 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CEP07975.1 - 0.0022 17.6 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 CEP07975.1 - 0.019 14.3 0.0 0.048 13.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 CEP07975.1 - 0.16 11.4 0.0 0.36 10.1 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Ribosomal_S3Ae PF01015.13 CEP07976.1 - 1.7e-75 252.6 7.7 2.3e-75 252.2 5.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF496 PF04363.7 CEP07976.1 - 1.2 9.0 5.4 15 5.4 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF496) Ribosomal_S3_C PF00189.15 CEP07977.1 - 9.7e-14 51.3 0.1 1.8e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CEP07977.1 - 7.5e-13 47.8 0.1 1.2e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CEP07977.1 - 0.0067 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Rpp20 PF12328.3 CEP07978.1 - 1.4e-11 44.2 0.9 5.3e-07 29.3 0.0 2.1 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CEP07978.1 - 7.3e-08 31.9 0.7 1.1e-07 31.2 0.5 1.3 1 0 0 1 1 1 1 Alba DUF633 PF04816.7 CEP07978.1 - 0.0037 16.6 0.7 0.0082 15.5 0.2 1.6 1 1 1 2 2 2 1 Family of unknown function (DUF633) NTR2 PF15458.1 CEP07979.1 - 1.1e-34 119.8 15.7 1.1e-34 119.8 10.9 2.9 3 0 0 3 3 3 1 Nineteen complex-related protein 2 GCFC PF07842.7 CEP07979.1 - 1.2e-13 51.0 0.9 8.9e-13 48.2 0.2 2.8 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein Tim44 PF04280.10 CEP07980.1 - 1.1e-22 80.6 0.1 1.6e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.6 CEP07980.1 - 1.3e-10 40.4 0.4 1.7e-10 40.1 0.3 1.1 1 0 0 1 1 1 1 MBA1-like protein Peptidase_M24 PF00557.19 CEP07981.1 - 6.5e-44 149.9 0.0 8.4e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CEP07981.1 - 6.1e-14 51.5 0.0 1.7e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain RRF PF01765.14 CEP07982.1 - 3.9e-50 169.5 7.5 3.9e-50 169.5 5.2 1.5 2 0 0 2 2 2 1 Ribosome recycling factor ApoL PF05461.6 CEP07982.1 - 0.0025 17.1 7.8 0.0031 16.8 0.3 2.1 2 0 0 2 2 2 1 Apolipoprotein L Nup88 PF10168.4 CEP07982.1 - 0.023 12.5 4.6 0.034 11.9 3.2 1.2 1 0 0 1 1 1 0 Nuclear pore component HTH_WhiA PF02650.9 CEP07982.1 - 0.027 14.8 0.8 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 WhiA C-terminal HTH domain GlutR_dimer PF00745.15 CEP07982.1 - 0.21 11.5 4.4 4 7.4 1.1 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4422 PF14393.1 CEP07982.1 - 0.25 10.8 3.9 0.15 11.6 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4422) KMP11 PF03037.11 CEP07982.1 - 0.32 11.5 10.1 2.8 8.6 1.2 2.8 2 1 1 3 3 3 0 Kinetoplastid membrane protein 11 Adaptin_binding PF10199.4 CEP07982.1 - 0.84 9.9 7.8 0.71 10.1 1.0 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF883 PF05957.8 CEP07982.1 - 1 9.8 7.8 0.31 11.4 1.9 2.7 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) AIF_C PF14721.1 CEP07982.1 - 1.3 9.3 5.4 1.6 9.0 0.2 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2611 PF11022.3 CEP07982.1 - 3 7.9 5.8 0.88 9.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2611) CRAL_TRIO PF00650.15 CEP07983.1 - 4.5e-31 107.4 0.1 7.5e-31 106.7 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Cyclin PF08613.6 CEP07984.1 - 1.4e-05 25.5 0.1 1.4e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CEP07984.1 - 0.0063 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DPBB_1 PF03330.13 CEP07985.1 - 1.6e-13 50.4 0.1 1.6e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP07985.1 - 1.5e-08 34.2 1.3 2.5e-08 33.6 0.1 1.9 1 1 0 2 2 2 1 Barwin family DUF572 PF04502.8 CEP07985.1 - 0.0049 16.1 14.4 0.0058 15.8 10.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Peptidase_S49_N PF08496.5 CEP07985.1 - 0.026 14.3 5.6 0.04 13.7 3.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2909 PF11137.3 CEP07985.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) PIH1 PF08190.7 CEP07985.1 - 0.056 12.8 5.8 0.069 12.5 4.0 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 TMEM51 PF15345.1 CEP07985.1 - 0.094 12.3 7.4 0.15 11.7 5.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Pro-rich PF15240.1 CEP07985.1 - 0.39 10.8 7.9 2.4 8.2 5.5 2.0 1 1 0 1 1 1 0 Proline-rich DUF2413 PF10310.4 CEP07985.1 - 0.46 9.2 14.9 0.5 9.1 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Conotoxin PF02950.12 CEP07985.1 - 0.62 10.8 8.3 0.75 10.6 0.0 2.9 2 1 1 3 3 2 0 Conotoxin CDC73 PF05179.9 CEP07985.1 - 1.4 8.1 7.6 1.8 7.8 5.3 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family DUF2217 PF10265.4 CEP07985.1 - 2.6 6.7 11.8 3.2 6.4 8.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Dicty_REP PF05086.7 CEP07985.1 - 2.8 5.5 11.9 3.2 5.3 8.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_viral_N PF00242.12 CEP07985.1 - 3.3 6.6 16.9 4 6.3 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CEP07985.1 - 3.5 5.7 24.1 4.2 5.5 16.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 CEP07985.1 - 3.9 7.3 10.5 2 8.2 5.9 1.4 1 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.10 CEP07985.1 - 7 6.6 11.7 2.3e+02 1.7 8.1 2.3 1 1 0 1 1 1 0 Ctr copper transporter family SOBP PF15279.1 CEP07985.1 - 7.2 6.9 13.0 9 6.5 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Aa_trans PF01490.13 CEP07987.1 - 6.7e-59 199.3 29.9 8.6e-59 199.0 20.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HMG_box PF00505.14 CEP07987.1 - 1.3e-22 79.7 1.3 3.1e-22 78.5 0.9 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP07987.1 - 9.5e-14 51.5 1.4 2.4e-13 50.2 1.0 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CEP07987.1 - 0.35 10.6 5.4 0.04 13.7 0.7 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF3509 PF12021.3 CEP07988.1 - 0.052 13.3 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) TB2_DP1_HVA22 PF03134.14 CEP07989.1 - 2.4e-22 78.4 7.7 4.6e-22 77.5 5.3 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family NIPSNAP PF07978.8 CEP07990.1 - 4.3e-23 81.2 0.1 2.5e-11 43.4 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP KilA-N PF04383.8 CEP07990.1 - 0.059 12.9 0.4 0.09 12.3 0.3 1.3 1 0 0 1 1 1 0 KilA-N domain Ketoacyl-synt_C PF02801.17 CEP07991.1 - 1e-36 125.3 0.3 1.7e-36 124.6 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 CEP07991.1 - 1.7e-30 106.3 2.2 2.9e-30 105.6 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 CEP07991.1 - 1.7e-06 27.2 0.0 2.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEP07991.1 - 0.00057 19.3 3.7 0.0056 16.1 0.1 3.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain Haem_oxygenas_2 PF14518.1 CEP07991.1 - 0.07 13.2 0.0 3.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Iron-containing redox enzyme AMP-binding PF00501.23 CEP07992.1 - 8.5e-94 314.2 0.0 1.1e-93 313.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP07992.1 - 2.4e-10 41.1 0.1 8.3e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hist_deacetyl PF00850.14 CEP07993.1 - 1e-50 172.7 0.1 5.8e-29 101.3 0.0 2.0 2 0 0 2 2 2 2 Histone deacetylase domain bZIP_1 PF00170.16 CEP07994.1 - 1.3e-09 37.8 11.6 3.2e-09 36.5 8.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP07994.1 - 5.6e-07 29.2 11.0 5.6e-07 29.2 7.6 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CEP07994.1 - 0.0045 17.2 6.5 0.012 15.8 4.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-Q PF13094.1 CEP07994.1 - 8.7 6.3 11.4 15 5.6 6.6 2.1 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fork_head PF00250.13 CEP07995.1 - 3.4e-27 94.3 3.6 1.9e-26 91.8 2.5 2.2 1 1 0 1 1 1 1 Fork head domain Macoilin PF09726.4 CEP07995.1 - 0.038 12.2 10.9 0.055 11.7 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein HTH_32 PF13565.1 CEP07995.1 - 0.074 13.8 1.8 0.23 12.2 1.2 1.9 1 0 0 1 1 1 0 Homeodomain-like domain CRT10 PF08728.5 CEP07995.1 - 0.25 9.3 9.7 0.35 8.8 6.7 1.1 1 0 0 1 1 1 0 CRT10 TFIIA PF03153.8 CEP07995.1 - 2.2 8.0 28.9 1.1 9.1 12.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CEP07995.1 - 7.5 5.8 28.1 2.2 7.5 9.9 2.3 2 0 0 2 2 2 0 Vta1 like Mito_carr PF00153.22 CEP07996.1 - 8.3e-64 211.3 0.9 2.1e-21 75.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.2 CEP07997.1 - 2e-34 119.4 0.0 2.8e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP07997.1 - 5.7e-27 94.7 0.0 1.5e-25 90.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP07997.1 - 1.8e-19 69.9 0.0 1.6e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CEP07997.1 - 3.5e-07 30.0 0.1 0.00078 19.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 CEP07997.1 - 9.2e-07 28.5 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.8 CEP07997.1 - 2.8e-06 27.0 0.0 1.5e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Thioesterase PF00975.15 CEP07997.1 - 1.2e-05 25.6 0.1 0.00016 21.9 0.1 2.3 2 1 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.20 CEP07997.1 - 7.5e-05 22.3 0.0 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) Ndr PF03096.9 CEP07997.1 - 0.00026 19.5 0.0 0.00063 18.3 0.0 1.6 2 0 0 2 2 2 1 Ndr family Chlorophyllase2 PF12740.2 CEP07997.1 - 0.0017 17.2 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme UPF0227 PF05728.7 CEP07997.1 - 0.0018 18.0 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.3 CEP07997.1 - 0.01 15.6 0.0 0.036 13.9 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_8 PF06259.7 CEP07997.1 - 0.018 14.5 0.0 0.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_2 PF02230.11 CEP07997.1 - 0.029 13.8 0.0 0.53 9.6 0.0 2.4 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CEP07997.1 - 0.1 12.2 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ABC1 PF03109.11 CEP07998.1 - 0.78 9.7 5.6 4 7.4 3.8 2.2 1 1 1 2 2 2 0 ABC1 family HEAT PF02985.17 CEP07999.1 - 3.5e-44 144.9 12.2 0.00025 20.8 0.0 11.1 11 0 0 11 11 11 10 HEAT repeat HEAT_2 PF13646.1 CEP07999.1 - 1e-28 99.4 3.0 3.8e-07 30.2 0.0 5.1 3 1 2 5 5 5 5 HEAT repeats Vac14_Fab1_bd PF12755.2 CEP07999.1 - 3.6e-08 33.6 0.1 1.1 9.6 0.0 5.6 1 1 5 6 6 6 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CEP07999.1 - 8.7e-08 32.4 11.0 0.0023 18.3 0.2 7.5 5 4 3 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.15 CEP07999.1 - 1.9e-07 29.8 2.9 0.016 13.5 0.0 3.0 1 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 CEP07999.1 - 9.7e-05 21.8 0.7 3 7.1 0.0 4.5 2 2 3 5 5 5 1 CLASP N terminal DNA_alkylation PF08713.6 CEP07999.1 - 0.002 17.6 0.2 0.27 10.7 0.0 3.1 3 1 0 3 3 3 1 DNA alkylation repair enzyme Ecm29 PF13001.2 CEP07999.1 - 0.008 14.7 0.9 2.2 6.6 0.0 3.2 3 1 0 3 3 3 2 Proteasome stabiliser DUF2435 PF10363.4 CEP07999.1 - 0.01 15.7 0.8 1.6 8.6 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) M11L PF11099.3 CEP07999.1 - 0.019 14.6 0.1 9.3 5.9 0.0 2.7 2 0 0 2 2 2 0 Apoptosis regulator M11L like Cohesin_HEAT PF12765.2 CEP07999.1 - 0.069 13.1 0.8 0.76 9.7 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.11 CEP07999.1 - 0.12 12.8 0.2 5.8 7.6 0.0 4.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat RasGAP PF00616.14 CEP08000.1 - 6.2e-41 140.2 0.1 6.2e-41 140.2 0.1 2.6 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CEP08000.1 - 1.5e-34 118.6 1.4 1.5e-34 118.6 0.9 2.7 2 0 0 2 2 2 1 RasGAP C-terminus CH PF00307.26 CEP08000.1 - 4.6e-13 49.1 0.3 2.4e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 CEP08000.1 - 1.6e-08 33.4 1.8 0.25 11.0 0.0 4.3 4 0 0 4 4 4 3 IQ calmodulin-binding motif Pkinase PF00069.20 CEP08001.1 - 1.3e-70 237.5 0.0 1.7e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08001.1 - 3.4e-30 104.9 0.1 5.1e-30 104.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP08001.1 - 0.041 13.6 0.1 0.095 12.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-Nse PF11789.3 CEP08001.1 - 0.076 12.5 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ins_beta PF03488.9 CEP08001.1 - 0.25 11.1 2.1 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Sel1 PF08238.7 CEP08002.1 - 2.1e-48 161.6 18.5 1.7e-08 34.7 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat zf-UBR PF02207.15 CEP08006.1 - 1.1e-13 50.6 6.5 1.1e-13 50.6 4.5 3.8 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CEP08006.1 - 0.0002 21.0 11.8 0.0002 21.0 8.2 3.1 3 0 0 3 3 3 1 PHD-finger Hs1pro-1_C PF07014.7 CEP08006.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus FliD_N PF02465.13 CEP08006.1 - 1.3 9.4 10.3 4.2 7.7 4.9 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Myosin_head PF00063.16 CEP08007.1 - 2.3e-214 713.4 1.7 3.4e-214 712.8 1.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CEP08007.1 - 4.6e-40 137.0 0.1 8.2e-40 136.2 0.1 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 CEP08007.1 - 5.9e-16 57.5 0.6 1.3e-15 56.5 0.4 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP08007.1 - 1.6e-13 50.0 0.2 3.7e-13 48.8 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP08007.1 - 2.3e-11 43.0 0.1 5.7e-11 41.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CEP08007.1 - 9.9e-05 22.4 0.6 0.00024 21.2 0.4 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain IQ PF00612.22 CEP08007.1 - 0.0021 17.5 3.1 0.55 10.0 0.8 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 CEP08007.1 - 0.0047 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP08007.1 - 0.019 15.7 0.0 0.088 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CEP08007.1 - 0.02 14.0 1.6 0.03 13.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 CEP08007.1 - 0.034 13.5 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Hpr_kinase_C PF07475.7 CEP08007.1 - 0.043 13.1 0.2 6.3 6.0 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SH3_4 PF06347.8 CEP08007.1 - 0.066 12.7 0.2 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_16 PF13191.1 CEP08007.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 CEP08007.1 - 0.081 12.4 0.3 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CEP08007.1 - 0.095 13.0 0.0 0.34 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP08007.1 - 0.16 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CAF1 PF04857.15 CEP08008.1 - 3.2e-49 167.6 2.1 5.3e-49 166.9 1.5 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease RNase_T PF00929.19 CEP08008.1 - 0.054 13.7 0.3 2.9 8.1 0.1 2.9 3 0 0 3 3 3 0 Exonuclease SR-25 PF10500.4 CEP08008.1 - 8.3 5.8 18.7 0.36 10.2 8.9 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PALP PF00291.20 CEP08009.1 - 1.2e-53 182.3 0.1 1.5e-53 182.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BCS1_N PF08740.6 CEP08010.1 - 3.6e-37 127.8 0.0 6.1e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CEP08010.1 - 2.6e-20 72.9 0.0 5.5e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEP08010.1 - 0.0003 21.6 0.0 0.00075 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CEP08010.1 - 0.0017 17.3 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CEP08010.1 - 0.0081 16.0 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEP08010.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CEP08010.1 - 0.021 14.5 0.0 0.057 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 CEP08010.1 - 0.043 12.9 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 CEP08010.1 - 0.1 12.7 0.0 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CEP08010.1 - 0.1 12.0 0.2 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 CEP08010.1 - 0.11 12.8 0.1 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DeoC PF01791.4 CEP08011.1 - 9.1e-45 152.7 3.0 1e-44 152.6 2.1 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.16 CEP08011.1 - 0.04 13.1 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 CEP08011.1 - 0.11 11.4 1.5 0.5 9.2 0.0 2.2 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase HTH_6 PF01418.12 CEP08011.1 - 0.12 12.1 0.5 6.4 6.5 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain, rpiR family ADK PF00406.17 CEP08012.1 - 7e-58 194.7 0.0 8.2e-58 194.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CEP08012.1 - 1.8e-14 53.0 0.0 3.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CEP08012.1 - 1.5e-05 25.7 0.0 3.4e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP08012.1 - 0.00035 20.4 0.0 0.0013 18.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CEP08012.1 - 0.0013 17.8 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CEP08012.1 - 0.0063 16.8 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CEP08012.1 - 0.082 12.3 0.0 0.23 10.8 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein Methyltransf_28 PF02636.12 CEP08013.1 - 7.1e-35 120.6 0.0 1.1e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 CEP08013.1 - 0.026 14.9 0.0 0.083 13.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PI3_PI4_kinase PF00454.22 CEP08014.1 - 1.2e-38 132.9 0.0 4.1e-38 131.1 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CEP08014.1 - 4.1e-22 78.2 0.0 1.4e-21 76.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PRP38 PF03371.10 CEP08015.1 - 1e-43 148.9 0.3 1.4e-43 148.5 0.2 1.1 1 0 0 1 1 1 1 PRP38 family SET PF00856.23 CEP08016.1 - 2.5e-07 31.1 0.0 2.7e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 SET domain WD40 PF00400.27 CEP08017.1 - 3.8e-87 283.3 23.6 3.4e-13 48.9 0.6 7.8 7 1 1 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP08017.1 - 1.3e-08 33.4 6.6 0.013 13.6 0.1 5.5 3 1 3 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CEP08017.1 - 2.7e-07 29.7 5.1 0.62 8.7 0.0 5.0 2 2 3 5 5 5 4 Nup133 N terminal like eIF2A PF08662.6 CEP08017.1 - 1.9e-06 27.7 0.1 0.094 12.4 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CEP08017.1 - 0.0061 14.9 0.2 1.3 7.2 0.0 3.1 2 1 0 3 3 3 1 Cytochrome D1 heme domain LisH PF08513.6 CEP08017.1 - 0.01 15.5 0.1 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 LisH JTB PF05439.7 CEP08018.1 - 0.0022 17.7 4.8 0.49 10.1 0.1 2.2 1 1 1 2 2 2 2 Jumping translocation breakpoint protein (JTB) TcpE PF12648.2 CEP08019.1 - 0.18 11.9 5.0 0.23 11.5 0.5 2.2 2 0 0 2 2 2 0 TcpE family BRI3BP PF14965.1 CEP08019.1 - 0.38 10.0 5.0 0.052 12.9 0.5 1.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF2975 PF11188.3 CEP08019.1 - 2.4 7.8 9.6 1.4 8.6 4.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) T_cell_tran_alt PF15128.1 CEP08019.1 - 2.5 7.5 6.2 0.76 9.2 0.6 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3180 PF11377.3 CEP08020.1 - 4.4 7.1 10.0 4.2 7.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) UBA PF00627.26 CEP08021.1 - 1e-07 31.5 2.6 2e-06 27.4 0.7 2.7 2 0 0 2 2 2 1 UBA/TS-N domain DUF3250 PF11618.3 CEP08021.1 - 1.2e-05 25.4 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3250) UBA_4 PF14555.1 CEP08021.1 - 0.0084 15.6 0.2 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain DUF1771 PF08590.5 CEP08021.1 - 3.3 7.7 13.2 0.092 12.7 0.8 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) RRM_6 PF14259.1 CEP08022.1 - 2.6e-10 40.1 0.0 5.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP08022.1 - 9.4e-09 34.7 0.0 2.4e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP08022.1 - 0.0097 15.7 0.1 0.026 14.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Wzt_C PF14524.1 CEP08023.1 - 0.18 11.4 14.5 41 3.8 0.0 7.8 5 2 3 8 8 8 0 Wzt C-terminal domain Lectin_C PF00059.16 CEP08023.1 - 0.25 11.9 0.0 0.55 10.8 0.0 1.5 1 0 0 1 1 1 0 Lectin C-type domain RhoGEF PF00621.15 CEP08024.1 - 3.3e-16 59.6 0.1 7.7e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain zf-C2H2 PF00096.21 CEP08025.1 - 5.9 7.4 6.2 7.9 7.0 0.4 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sec2p PF06428.6 CEP08026.1 - 2.7e-13 49.6 12.2 2.7e-13 49.6 8.5 2.3 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p GAS PF13851.1 CEP08026.1 - 0.0085 15.3 15.5 0.018 14.2 10.7 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding IncA PF04156.9 CEP08026.1 - 0.034 13.7 18.3 0.011 15.4 9.6 2.1 2 0 0 2 2 2 0 IncA protein Histone PF00125.19 CEP08026.1 - 0.062 13.4 0.4 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Tropomyosin_1 PF12718.2 CEP08026.1 - 0.16 11.8 20.4 0.019 14.7 10.7 2.0 2 0 0 2 2 2 0 Tropomyosin like DUF2232 PF09991.4 CEP08026.1 - 0.19 10.7 0.2 0.3 10.0 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TMF_DNA_bd PF12329.3 CEP08026.1 - 0.82 9.5 21.2 0.029 14.1 5.4 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 CEP08026.1 - 0.96 7.2 7.0 1.3 6.8 4.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 CEP08026.1 - 6.5 5.6 12.9 15 4.4 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.7 CEP08026.1 - 9.4 4.5 7.6 13 4.1 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PSP1 PF04468.7 CEP08026.1 - 9.7 6.2 9.3 0.87 9.6 0.4 3.0 1 1 1 2 2 2 0 PSP1 C-terminal conserved region DUF1772 PF08592.6 CEP08027.1 - 2.1e-16 59.9 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) UPF0183 PF03676.9 CEP08028.1 - 1e-67 228.4 1.3 8.2e-54 182.6 0.3 3.1 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) IPK PF03770.11 CEP08029.1 - 6.2e-49 166.3 0.0 9.4e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase RVT_1 PF00078.22 CEP08031.1 - 2.1e-06 27.2 0.1 2.4e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC1 PF03109.11 CEP08032.1 - 2e-21 76.1 0.0 3.5e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 ABC1 family PCI_Csn8 PF10075.4 CEP08033.1 - 2.8e-24 85.5 0.2 3.7e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CEP08033.1 - 3.9e-22 78.8 0.3 5.4e-22 78.3 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 CEP08033.1 - 0.11 12.7 0.0 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 PCI domain PHO4 PF01384.15 CEP08035.1 - 5.3e-113 376.9 20.0 6.6e-113 376.6 13.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family Nbl1_Borealin_N PF10444.4 CEP08038.1 - 0.00031 20.0 2.5 0.0047 16.2 0.0 3.4 4 0 0 4 4 4 1 Nbl1 / Borealin N terminal Noggin PF05806.7 CEP08038.1 - 0.099 11.9 0.3 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 Noggin AIP3 PF03915.8 CEP08038.1 - 0.22 10.3 19.3 0.026 13.4 7.8 2.0 1 1 1 2 2 2 0 Actin interacting protein 3 GA PF01468.12 CEP08038.1 - 1.8 8.7 6.4 0.3 11.2 1.0 2.3 2 0 0 2 2 2 0 GA module AMP-binding PF00501.23 CEP08039.1 - 1.3e-85 287.3 0.0 1.6e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme His_Phos_1 PF00300.17 CEP08040.1 - 2.9e-19 69.7 0.0 3.5e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RNase_PH PF01138.16 CEP08041.1 - 1.1e-34 119.5 0.1 1.9e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CEP08041.1 - 0.00087 19.1 0.2 0.0021 17.9 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Nup54 PF13874.1 CEP08042.1 - 0.021 14.5 0.0 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Vezatin PF12632.2 CEP08042.1 - 0.12 11.4 10.1 0.045 12.8 0.6 3.1 3 0 0 3 3 3 0 Mysoin-binding motif of peroxisomes Acetyltransf_1 PF00583.19 CEP08043.1 - 1.3e-09 37.9 0.0 2.9e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP08043.1 - 1.5e-07 31.4 0.2 2.9e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP08043.1 - 0.0084 15.8 0.1 0.02 14.6 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CEP08043.1 - 0.031 14.1 0.1 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PTPA PF03095.10 CEP08044.1 - 5e-79 265.5 0.1 3.6e-71 239.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein Arrestin_N PF00339.24 CEP08044.1 - 4.8e-11 42.6 0.0 1.2e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 CEP08044.1 - 0.047 12.7 0.2 0.084 11.9 0.2 1.3 1 0 0 1 1 1 0 Rgp1 DUF3589 PF12141.3 CEP08044.1 - 0.11 10.7 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3589) Methyltransf_11 PF08241.7 CEP08045.1 - 2.3e-13 50.4 0.0 5.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP08045.1 - 3.9e-13 49.2 0.0 1.9e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP08045.1 - 1.7e-10 40.8 0.0 3.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP08045.1 - 1.6e-08 33.9 0.0 6.4e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEP08045.1 - 1.8e-08 34.6 0.0 4.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP08045.1 - 3.6e-07 30.5 0.0 1e-06 29.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CEP08045.1 - 4.1e-05 23.3 0.0 7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 CEP08045.1 - 4.2e-05 24.1 0.0 0.00021 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 CEP08045.1 - 0.0012 17.2 0.0 0.0027 16.1 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF508 PF04370.7 CEP08045.1 - 0.045 13.3 1.7 0.079 12.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Methyltransf_26 PF13659.1 CEP08045.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF202 PF02656.10 CEP08046.1 - 1.5e-22 79.6 0.1 1.5e-22 79.6 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2975 PF11188.3 CEP08046.1 - 0.0021 17.7 1.8 0.0027 17.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) NfeD PF01957.13 CEP08046.1 - 0.7 10.0 3.9 1 9.4 2.7 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding EF-hand_7 PF13499.1 CEP08048.1 - 4.2e-20 71.6 5.4 3.1e-12 46.4 0.7 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP08048.1 - 1.7e-19 67.8 11.0 2.4e-05 23.8 0.3 5.0 3 2 2 5 5 5 4 EF-hand domain EF-hand_1 PF00036.27 CEP08048.1 - 1.5e-17 61.4 19.7 2e-05 23.5 1.1 4.7 4 1 1 5 5 5 4 EF hand EF-hand_5 PF13202.1 CEP08048.1 - 3.4e-15 54.5 13.7 2e-05 23.7 1.3 4.4 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.1 CEP08048.1 - 1.3e-14 53.5 9.5 1.4e-07 31.0 0.3 3.5 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.2 CEP08048.1 - 7.7e-06 25.5 8.8 0.24 11.1 0.4 3.8 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand DUF1707 PF08044.6 CEP08048.1 - 0.087 12.5 0.0 3.9 7.3 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) Toprim PF01751.17 CEP08048.1 - 0.13 12.2 0.0 3.5 7.6 0.0 2.5 1 1 0 1 1 1 0 Toprim domain EF-hand_9 PF14658.1 CEP08048.1 - 0.27 11.1 1.8 21 5.1 0.0 3.3 2 1 0 3 3 3 0 EF-hand domain Ras PF00071.17 CEP08049.1 - 4e-48 162.8 0.1 6.3e-48 162.2 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP08049.1 - 3.6e-15 56.4 0.1 1.1e-14 54.9 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CEP08049.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CEP08049.1 - 0.0014 17.8 0.1 0.0021 17.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family NPR3 PF03666.8 CEP08050.1 - 8.9e-100 334.3 3.1 8.9e-100 334.3 2.1 2.0 1 1 1 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Glyco_tranf_2_3 PF13641.1 CEP08051.1 - 3.1e-19 69.6 0.3 3.4e-14 53.1 0.4 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 CEP08051.1 - 3.8e-12 45.3 9.6 6.5e-07 28.1 6.1 3.5 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP08051.1 - 1.8e-10 40.8 12.4 4.1e-10 39.6 8.6 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CEP08051.1 - 1.2e-06 28.3 0.0 0.026 14.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP08051.1 - 4.2e-05 22.8 0.3 0.0001 21.6 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 RAP1 PF07218.6 CEP08051.1 - 4.3 5.3 4.1 6.2 4.7 2.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mss4 PF04421.8 CEP08052.1 - 5.1e-17 61.4 0.1 6.1e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 Mss4 protein DUF883 PF05957.8 CEP08053.1 - 0.0099 16.2 4.1 0.0099 16.2 2.9 8.3 5 2 3 9 9 9 4 Bacterial protein of unknown function (DUF883) SHP PF03579.8 CEP08054.1 - 0.012 14.9 0.5 0.012 14.9 0.3 1.8 2 0 0 2 2 2 0 Small hydrophobic protein Grp1_Fun34_YaaH PF01184.14 CEP08054.1 - 0.02 14.1 2.3 0.033 13.4 1.6 1.4 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family ATP-synt_8 PF00895.15 CEP08054.1 - 2.1 8.6 0.0 2.1 8.6 0.0 2.9 3 1 0 3 3 3 0 ATP synthase protein 8 SR-25 PF10500.4 CEP08055.1 - 0.33 10.4 6.4 0.36 10.2 4.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.7 CEP08055.1 - 3.9 5.6 6.5 4.7 5.3 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EIIBC-GUT_N PF03612.9 CEP08056.1 - 0.22 11.1 4.1 3 7.4 4.0 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus LIM_bind PF01803.11 CEP08057.1 - 1.3e-40 138.9 0.0 1.3e-40 138.9 0.0 5.6 3 3 1 4 4 4 1 LIM-domain binding protein PAT1 PF09770.4 CEP08057.1 - 1.6 6.8 151.0 0.78 7.8 58.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Sel1 PF08238.7 CEP08059.1 - 2.3e-34 117.0 24.7 2.4e-08 34.3 0.1 7.8 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 CEP08059.1 - 0.067 13.6 0.5 0.067 13.6 0.4 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP08059.1 - 4.1 7.4 5.6 2.3 8.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TSC22 PF01166.13 CEP08060.1 - 0.0079 16.1 1.0 0.0079 16.1 0.7 2.9 2 1 0 2 2 2 1 TSC-22/dip/bun family DMPK_coil PF08826.5 CEP08060.1 - 0.012 15.5 1.3 0.012 15.5 0.9 3.2 2 1 0 3 3 3 0 DMPK coiled coil domain like Atg14 PF10186.4 CEP08060.1 - 1.3 7.9 17.9 1.4 7.7 12.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Imm36 PF15597.1 CEP08060.1 - 1.4 9.1 6.0 0.6 10.3 1.2 2.3 2 0 0 2 2 2 0 Immunity protein 36 Toxin_39 PF15500.1 CEP08060.1 - 1.7 8.8 6.9 0.42 10.7 2.2 1.9 2 0 0 2 2 2 0 Putative RNase-like toxin DUF4407 PF14362.1 CEP08060.1 - 2.3 7.0 11.9 2.6 6.9 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 CEP08060.1 - 7.5 6.5 8.2 1.8 8.5 0.2 3.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.1 CEP08060.1 - 8.8 6.1 15.3 17 5.2 2.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Robl_LC7 PF03259.12 CEP08061.1 - 0.0012 18.3 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain GrpE PF01025.14 CEP08062.1 - 1.2e-45 155.0 3.1 1.6e-45 154.6 2.1 1.1 1 0 0 1 1 1 1 GrpE Perilipin PF03036.11 CEP08062.1 - 0.0019 17.1 0.6 0.0025 16.7 0.4 1.1 1 0 0 1 1 1 1 Perilipin family SF-assemblin PF06705.6 CEP08062.1 - 0.038 13.1 4.9 0.029 13.5 1.8 1.6 1 1 1 2 2 2 0 SF-assemblin/beta giardin TPD52 PF04201.10 CEP08062.1 - 0.042 13.5 5.2 0.1 12.2 3.7 1.5 1 1 0 1 1 1 0 Tumour protein D52 family YjcZ PF13990.1 CEP08062.1 - 0.049 12.7 1.9 0.079 12.0 1.3 1.3 1 1 0 1 1 1 0 YjcZ-like protein DUF3510 PF12022.3 CEP08062.1 - 0.091 12.8 1.8 0.17 11.9 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Baculo_PEP_C PF04513.7 CEP08062.1 - 0.36 10.6 3.5 0.56 10.0 0.7 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 CEP08062.1 - 0.67 10.1 6.7 0.17 12.0 0.2 2.2 1 1 1 2 2 2 0 Syntaxin Prominin PF05478.6 CEP08062.1 - 3 5.2 5.0 3.9 4.8 3.5 1.0 1 0 0 1 1 1 0 Prominin Nramp PF01566.13 CEP08063.1 - 3.8e-92 308.8 21.7 1.8e-47 161.8 4.0 3.0 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein DUF2453 PF10507.4 CEP08063.1 - 0.02 14.6 0.7 0.059 13.1 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) ArfGap PF01412.13 CEP08064.1 - 5e-37 126.2 0.2 1.1e-36 125.1 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Dynamin_N PF00350.18 CEP08065.1 - 2e-19 70.0 0.0 7e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 CEP08065.1 - 2.2e-16 59.4 0.0 1.1e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 CEP08065.1 - 1.1e-08 34.9 0.0 3.4e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEP08065.1 - 2.3e-05 23.6 0.0 3.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP08065.1 - 3.1e-05 24.4 0.0 0.034 14.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 CEP08065.1 - 3.9e-05 23.1 0.0 0.0001 21.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_1 PF00036.27 CEP08065.1 - 0.0003 19.8 0.0 0.0011 18.1 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CEP08065.1 - 0.014 15.1 0.0 0.093 12.6 0.0 2.4 3 0 0 3 3 2 0 EF-hand domain UPF0079 PF02367.12 CEP08065.1 - 0.063 12.9 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRPRB PF09439.5 CEP08065.1 - 0.074 12.2 0.1 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.17 CEP08065.1 - 0.081 12.3 0.2 11 5.4 0.1 2.3 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.1 CEP08065.1 - 0.1 12.5 0.0 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Yip1 PF04893.12 CEP08066.1 - 1.1e-18 67.2 12.0 1.6e-18 66.7 8.3 1.1 1 0 0 1 1 1 1 Yip1 domain DUF997 PF06196.7 CEP08066.1 - 0.54 9.7 4.7 1.4 8.5 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF1282 PF06930.7 CEP08066.1 - 1.8 8.2 12.8 3.6 7.2 8.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) TRAPP PF04051.11 CEP08067.1 - 2.3e-42 144.0 0.0 2.8e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Kelch_3 PF13415.1 CEP08068.1 - 1.5e-19 69.5 0.1 4.8e-09 36.1 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP08068.1 - 2.6e-19 68.7 0.0 1.3e-05 24.8 0.0 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP08068.1 - 7e-18 63.9 0.1 8.5e-08 32.0 0.0 3.8 1 1 2 3 3 3 3 Kelch motif Kelch_5 PF13854.1 CEP08068.1 - 1.3e-16 60.1 0.0 3.5e-06 26.8 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 CEP08068.1 - 9.4e-14 50.5 0.0 4.3e-05 23.0 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 CEP08068.1 - 4.6e-08 32.4 0.0 0.00019 20.8 0.0 2.7 2 0 0 2 2 2 2 Kelch motif BTB PF00651.26 CEP08068.1 - 2.8e-05 24.0 0.1 7.6e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain DUF2738 PF10927.3 CEP08068.1 - 0.0065 15.5 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2738) Pkinase PF00069.20 CEP08069.1 - 7.6e-70 235.0 0.1 9.6e-70 234.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08069.1 - 7.4e-32 110.4 0.0 1.1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP08069.1 - 8.4e-06 24.9 0.1 0.00013 21.0 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CEP08069.1 - 0.0011 18.7 0.1 0.57 9.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CEP08069.1 - 0.0054 16.1 3.5 0.056 12.7 2.4 2.1 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 CEP08069.1 - 0.019 14.3 0.4 0.2 10.9 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PH PF00169.24 CEP08070.1 - 6.5e-07 29.5 0.1 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 CEP08070.1 - 4.7e-06 26.7 0.0 1.5e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain TFIIS_M PF07500.9 CEP08071.1 - 5.9e-22 77.8 1.0 2.1e-21 76.1 0.7 2.0 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 CEP08071.1 - 5.6e-14 52.6 0.0 1.3e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 CEP08071.1 - 1.9e-10 40.2 14.4 4.1e-10 39.1 10.0 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEP08071.1 - 0.37 10.1 6.8 0.73 9.2 4.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 CEP08071.1 - 0.53 10.1 6.9 1.3 8.9 4.8 1.6 1 0 0 1 1 1 0 Ring finger domain IF-2B PF01008.12 CEP08072.1 - 2.6e-71 239.8 2.2 3.1e-71 239.6 1.6 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fungal_trans PF04082.13 CEP08073.1 - 6.7e-08 31.7 1.0 1.5e-07 30.5 0.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FlxA PF14282.1 CEP08073.1 - 0.045 13.7 4.5 0.099 12.6 3.1 1.5 1 0 0 1 1 1 0 FlxA-like protein OCD_Mu_crystall PF02423.10 CEP08075.1 - 5.9e-57 192.8 2.7 7.2e-57 192.5 1.8 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 CEP08075.1 - 1.4e-06 28.4 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 CEP08075.1 - 0.006 17.0 0.0 0.022 15.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 CEP08075.1 - 0.049 13.8 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding PPR_3 PF13812.1 CEP08075.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain TRIC PF05197.8 CEP08076.1 - 0.0025 17.2 0.2 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 TRIC channel Luteo_coat PF00894.13 CEP08076.1 - 0.033 13.9 0.2 0.077 12.7 0.0 1.6 1 1 0 1 1 1 0 Luteovirus coat protein UVR PF02151.14 CEP08077.1 - 0.00079 18.8 11.5 0.0013 18.2 2.0 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif TAN PF11640.3 CEP08077.1 - 0.032 13.9 4.5 0.12 12.1 0.1 2.5 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair DUF3253 PF11625.3 CEP08077.1 - 0.06 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) DUF1620 PF07774.8 CEP08079.1 - 1.1e-63 214.3 0.0 2e-63 213.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CEP08079.1 - 1.2e-09 37.9 0.7 3e-07 30.1 0.2 2.3 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 CEP08079.1 - 0.2 11.2 2.0 57 3.5 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat Tetraspannin PF00335.15 CEP08080.1 - 4.6e-20 71.8 12.4 4.6e-20 71.8 8.6 1.8 2 0 0 2 2 2 1 Tetraspanin family VirB8 PF04335.8 CEP08080.1 - 0.12 11.9 0.8 0.27 10.7 0.5 1.5 1 0 0 1 1 1 0 VirB8 protein DUF4407 PF14362.1 CEP08080.1 - 0.46 9.4 5.2 0.77 8.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3098 PF11297.3 CEP08080.1 - 0.78 9.4 7.7 0.16 11.6 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Kelch_6 PF13964.1 CEP08081.1 - 4.1e-17 61.5 2.7 0.00019 21.4 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CEP08081.1 - 3.4e-16 58.7 4.4 6.8e-06 25.7 0.2 4.4 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP08081.1 - 5e-13 48.2 9.0 1.8e-05 24.3 0.4 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CEP08081.1 - 4.2e-12 45.8 2.0 0.00068 19.7 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP08081.1 - 1.2e-10 41.0 7.8 0.00024 20.9 0.3 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 CEP08081.1 - 7.8e-10 38.1 16.4 0.00029 20.2 0.1 5.9 6 1 0 6 6 6 3 Kelch motif TMEM223 PF14640.1 CEP08083.1 - 1.3e-20 74.0 0.1 1e-19 71.0 0.1 2.0 1 1 0 1 1 1 1 Transmembrane protein 223 PhoH PF02562.11 CEP08083.1 - 0.011 14.9 0.1 0.025 13.8 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein tRNA-synt_2d PF01409.15 CEP08084.1 - 1.1e-52 178.7 0.9 6.8e-30 104.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CEP08084.1 - 1.4e-24 86.0 0.0 3.5e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 CEP08084.1 - 0.019 13.7 0.5 2.1 7.0 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) PHD PF00628.24 CEP08085.1 - 1.8e-08 33.9 14.3 2.1e-08 33.7 7.6 2.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CEP08085.1 - 0.0025 17.0 3.3 0.0025 17.0 2.3 2.0 2 0 0 2 2 2 1 PHD-finger zf-C2H2_jaz PF12171.3 CEP08085.1 - 0.12 12.5 0.2 0.12 12.5 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Sgf11 PF08209.6 CEP08085.1 - 0.83 9.0 9.9 0.21 10.9 0.3 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-C2H2_4 PF13894.1 CEP08085.1 - 2.1 8.8 9.2 0.19 12.1 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Prok-RING_1 PF14446.1 CEP08085.1 - 2.5 7.8 11.2 0.26 11.0 2.4 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DEAD PF00270.24 CEP08086.1 - 5.6e-42 143.0 0.1 3.9e-41 140.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP08086.1 - 3.6e-25 87.6 0.1 8.9e-25 86.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4137 PF13593.1 CEP08087.1 - 3.3e-82 276.0 15.5 3.8e-82 275.8 10.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 CEP08087.1 - 2.2e-06 27.2 9.0 5e-06 26.0 6.3 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family DUF485 PF04341.7 CEP08089.1 - 2.4 7.9 8.3 1.5 8.5 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF485 DUF788 PF05620.6 CEP08089.1 - 7.8 6.3 6.5 16 5.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF788) Cactin_mid PF10312.4 CEP08090.1 - 2.1e-62 209.8 5.9 5.9e-62 208.3 4.1 1.8 1 0 0 1 1 1 1 Conserved mid region of cactin eIF-5a PF01287.15 CEP08090.1 - 0.024 14.5 5.2 1 9.3 0.2 3.3 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold CactinC_cactus PF09732.4 CEP08090.1 - 0.068 12.7 0.1 0.068 12.7 0.1 1.9 2 0 0 2 2 2 0 Cactus-binding C-terminus of cactin protein LRR_9 PF14580.1 CEP08091.1 - 2.1e-58 196.7 4.3 6.4e-58 195.1 2.7 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 CEP08091.1 - 2.9e-11 42.9 15.7 6.5e-09 35.4 4.3 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CEP08091.1 - 5.4e-07 29.0 18.5 0.001 18.6 1.4 4.2 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CEP08091.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CEP08091.1 - 0.12 12.4 10.1 18 5.7 2.5 4.7 4 1 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 CEP08091.1 - 0.73 10.0 13.1 0.44 10.7 0.3 5.1 6 1 0 6 6 6 0 Leucine Rich Repeat Caldesmon PF02029.10 CEP08092.1 - 0.31 9.4 6.2 0.36 9.2 4.3 1.0 1 0 0 1 1 1 0 Caldesmon muHD PF10291.4 CEP08093.1 - 1e-30 106.7 1.2 2.2e-30 105.6 0.8 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CEP08093.1 - 2.1e-11 43.8 4.6 2.4e-11 43.6 0.0 3.6 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain CHZ PF09649.5 CEP08093.1 - 1.4e-09 37.0 2.1 1.8e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ Pox_Ag35 PF03286.9 CEP08093.1 - 0.48 9.9 24.9 1.1 8.7 17.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_Rpb6 PF01192.17 CEP08094.1 - 4.1e-20 71.2 0.9 6e-20 70.7 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pribosyltran PF00156.22 CEP08094.1 - 0.088 12.5 0.0 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase domain EBA-175_VI PF11556.3 CEP08095.1 - 0.028 14.5 0.6 0.048 13.7 0.4 1.3 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 Pdase_C33_assoc PF14756.1 CEP08095.1 - 0.04 13.6 0.1 0.87 9.3 0.0 2.7 3 0 0 3 3 3 0 Peptidase_C33-associated domain MTHFR PF02219.12 CEP08095.1 - 0.11 11.5 0.7 0.37 9.8 0.1 1.8 1 1 0 2 2 2 0 Methylenetetrahydrofolate reductase Aminotran_1_2 PF00155.16 CEP08096.1 - 6.7e-43 147.0 0.0 8.2e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1206 PF06724.6 CEP08097.1 - 1.6e-21 75.7 21.4 1.3e-10 40.9 1.7 3.3 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) Steroid_dh PF02544.11 CEP08098.1 - 9.8e-34 116.2 5.2 9.8e-34 116.2 3.6 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase RRM_1 PF00076.17 CEP08100.1 - 4.7e-08 32.5 0.2 1.3e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP08100.1 - 5e-06 26.4 0.1 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3452 PF11934.3 CEP08100.1 - 0.11 11.8 1.0 0.42 9.9 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) DUF1324 PF07038.6 CEP08101.1 - 0.049 13.6 0.4 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) AATase PF07247.7 CEP08101.1 - 0.11 11.0 1.6 0.52 8.7 1.1 1.8 1 1 0 1 1 1 0 Alcohol acetyltransferase Mmp37 PF09139.6 CEP08102.1 - 5.4e-118 393.7 0.4 9.1e-118 393.0 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Sin_N PF04801.8 CEP08103.1 - 1e-45 156.3 7.6 1.2e-45 156.1 5.3 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region ATP_bind_1 PF03029.12 CEP08104.1 - 3.2e-80 269.0 0.0 3.8e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MobB PF03205.9 CEP08104.1 - 0.0026 17.4 0.0 0.0074 15.9 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CEP08104.1 - 0.0029 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CEP08104.1 - 0.0075 15.0 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 CEP08104.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 CEP08104.1 - 0.011 15.4 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 CEP08104.1 - 0.018 15.8 1.9 0.051 14.3 1.2 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CEP08104.1 - 0.023 14.6 0.4 0.11 12.4 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mac-1 PF09028.5 CEP08104.1 - 0.05 12.3 0.1 0.064 12.0 0.1 1.1 1 0 0 1 1 1 0 Mac 1 SRP54 PF00448.17 CEP08104.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 CEP08104.1 - 0.1 12.1 0.2 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CEP08104.1 - 0.11 11.9 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CEP08104.1 - 0.11 12.8 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CEP08104.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CEP08104.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Pil1 PF13805.1 CEP08105.1 - 8.7e-26 90.6 4.5 1.7e-25 89.7 3.1 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2802 PF10975.3 CEP08105.1 - 0.49 10.1 12.2 2.1 8.1 0.1 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2802) DUF2316 PF10078.4 CEP08105.1 - 1.8 8.6 6.2 0.31 11.0 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF342 PF03961.8 CEP08105.1 - 9 4.5 12.1 0.15 10.4 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) GIT_SHD PF08518.6 CEP08107.1 - 0.0021 17.3 2.9 0.11 11.9 0.1 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF2096 PF09869.4 CEP08107.1 - 0.003 17.4 3.1 0.16 11.8 0.2 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2096) Erythro_esteras PF05139.9 CEP08107.1 - 0.019 14.1 0.5 4.6 6.3 0.1 2.2 2 0 0 2 2 2 0 Erythromycin esterase FlaF PF07309.6 CEP08107.1 - 0.1 12.4 0.2 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FlaF Prefoldin_2 PF01920.15 CEP08107.1 - 0.11 12.2 1.7 4.1 7.2 0.1 2.9 2 1 0 2 2 2 0 Prefoldin subunit DUF818 PF05677.7 CEP08107.1 - 0.18 10.5 1.0 5.1 5.7 0.0 2.9 3 0 0 3 3 3 0 Chlamydia CHLPS protein (DUF818) YtxH PF12732.2 CEP08107.1 - 2.7 8.4 5.8 15 6.0 1.2 3.3 2 2 0 2 2 2 0 YtxH-like protein KID PF02524.9 CEP08107.1 - 3.3 8.2 5.6 10 6.7 0.3 3.8 2 0 0 2 2 2 0 KID repeat RRM_1 PF00076.17 CEP08108.1 - 3.3e-25 87.5 0.1 6.1e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP08108.1 - 2.1e-16 59.4 0.0 7.2e-08 32.1 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP08108.1 - 3.7e-15 55.6 0.1 1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CEP08109.1 - 1.8e-11 43.7 0.0 4.5e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08109.1 - 1.5e-05 24.2 0.1 9.1e-05 21.6 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase 7TM_GPCR_Srab PF10292.4 CEP08109.1 - 0.034 12.8 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor BUD22 PF09073.5 CEP08110.1 - 0.064 12.3 28.8 0.089 11.8 19.7 1.6 1 1 0 1 1 1 0 BUD22 SDA1 PF05285.7 CEP08110.1 - 0.073 12.3 18.1 0.0058 15.9 6.7 2.2 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 CEP08110.1 - 1.6 6.5 28.9 3.4 5.4 20.0 1.6 1 1 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 CEP08110.1 - 3.2 5.7 8.7 5.2 5.0 6.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIF_alpha PF05793.7 CEP08110.1 - 10 4.3 28.3 1.9 6.7 13.3 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Gly_transf_sug PF04488.10 CEP08112.1 - 4.4e-05 23.8 0.3 0.00011 22.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CEP08112.1 - 0.063 12.4 0.6 0.14 11.2 0.4 1.5 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Pkinase PF00069.20 CEP08113.1 - 5.5e-70 235.4 0.0 7e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08113.1 - 2.3e-36 125.2 0.0 3.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP08113.1 - 0.025 13.5 0.0 0.056 12.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DUF605 PF04652.11 CEP08113.1 - 1.8 7.9 14.9 2.4 7.4 10.3 1.2 1 0 0 1 1 1 0 Vta1 like Sugar_tr PF00083.19 CEP08114.1 - 3.1e-102 342.4 31.4 2.6e-51 174.6 5.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP08114.1 - 2.2e-20 72.7 42.4 6.9e-14 51.3 7.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TPR_21 PF09976.4 CEP08114.1 - 0.2 11.6 1.3 0.29 11.0 0.9 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat ArfGap PF01412.13 CEP08114.1 - 0.21 11.3 1.3 0.43 10.3 0.9 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf MFS_2 PF13347.1 CEP08114.1 - 5 5.3 40.9 0.027 12.8 6.5 3.7 2 2 2 4 4 4 0 MFS/sugar transport protein DUF3519 PF12033.3 CEP08115.1 - 0.51 10.5 3.3 2.1 8.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) Glyco_hydro_16 PF00722.16 CEP08116.1 - 3.1e-08 33.1 0.0 5.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Na_H_Exchanger PF00999.16 CEP08117.1 - 4.4e-54 183.4 45.0 1.6e-53 181.6 31.4 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family NPR3 PF03666.8 CEP08117.1 - 0.059 11.8 1.0 0.089 11.3 0.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase PF00069.20 CEP08118.1 - 2.2e-48 164.6 0.0 3e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08118.1 - 3.5e-24 85.2 0.0 4.5e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CEP08118.1 - 0.0001 21.2 0.0 0.00015 20.6 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CEP08118.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Asp PF00026.18 CEP08119.1 - 4.1e-17 62.4 0.0 7.9e-08 31.9 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CEP08119.1 - 0.037 14.5 0.0 18 5.9 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 CEP08119.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HisG PF01634.13 CEP08120.1 - 4.9e-47 159.5 0.4 7.4e-47 158.9 0.3 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CEP08120.1 - 2.3e-24 85.1 0.0 4.3e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain WD40 PF00400.27 CEP08121.1 - 1.3e-62 205.5 26.4 2.2e-11 43.1 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CEP08121.1 - 1.4e-05 24.9 0.1 8.4e-05 22.3 0.0 2.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CEP08121.1 - 2.7e-05 22.5 11.3 0.0021 16.2 0.5 4.5 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CEP08121.1 - 0.0041 15.4 0.0 1.2 7.3 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain SH3_1 PF00018.23 CEP08122.1 - 1e-16 60.0 0.0 1.9e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Peroxin-13_N PF04088.8 CEP08122.1 - 1.3e-15 57.6 1.0 1.8e-15 57.2 0.5 1.4 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 CEP08122.1 - 1.9e-13 49.7 0.0 3.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP08122.1 - 6e-12 44.8 0.0 1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain alpha-hel2 PF14456.1 CEP08122.1 - 0.028 13.2 0.3 4.2 6.0 0.0 2.3 3 0 0 3 3 3 0 Alpha-helical domain 2 hGDE_central PF14702.1 CEP08122.1 - 0.053 12.6 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 central domain of human glycogen debranching enzyme DUF239 PF03080.10 CEP08122.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF239) adh_short PF00106.20 CEP08123.1 - 3.7e-24 85.5 0.0 2.6e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CEP08123.1 - 5.2e-20 72.2 0.2 1.2e-19 71.0 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Chromo PF00385.19 CEP08123.1 - 9.4e-16 57.2 1.0 9.4e-16 57.2 0.7 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain KR PF08659.5 CEP08123.1 - 0.00016 21.3 0.1 0.00049 19.7 0.0 1.8 2 0 0 2 2 2 1 KR domain Chromo_shadow PF01393.14 CEP08123.1 - 0.026 14.3 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Chromo shadow domain NAD_binding_10 PF13460.1 CEP08123.1 - 0.043 13.8 0.0 7.5 6.5 0.0 2.6 2 1 0 2 2 2 0 NADH(P)-binding AT_hook PF02178.14 CEP08123.1 - 1.4 8.7 7.2 0.24 11.1 0.4 2.8 2 0 0 2 2 2 0 AT hook motif PAS PF00989.19 CEP08124.1 - 1.3e-05 24.9 0.0 3.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 CEP08124.1 - 5.9 6.8 7.5 0.26 11.2 1.1 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.13 CEP08125.1 - 3e-07 30.3 0.0 4.3e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP08125.1 - 0.0044 16.6 0.6 0.008 15.8 0.3 1.4 1 1 0 1 1 1 1 Barwin family Rib_hydrolayse PF02267.12 CEP08125.1 - 0.055 12.8 1.0 0.074 12.3 0.7 1.1 1 0 0 1 1 1 0 ADP-ribosyl cyclase Scramblase PF03803.10 CEP08125.1 - 0.065 12.2 0.1 0.087 11.8 0.1 1.1 1 0 0 1 1 1 0 Scramblase Alpha_E3_glycop PF01563.11 CEP08126.1 - 0.0097 15.6 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 2 1 Alphavirus E3 glycoprotein DUF1771 PF08590.5 CEP08127.1 - 2.5e-14 53.0 3.1 2.5e-14 53.0 2.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 CEP08127.1 - 1.5e-10 41.0 0.2 3.2e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 CEP08127.1 - 2.3e-05 23.9 7.8 0.00011 21.7 0.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 CEP08127.1 - 0.0076 15.7 0.5 0.016 14.6 0.4 1.5 1 0 0 1 1 1 1 CUE domain HBS1_N PF08938.5 CEP08127.1 - 0.013 15.6 0.6 0.013 15.6 0.4 2.9 2 1 0 2 2 2 0 HBS1 N-terminus YqfQ PF14181.1 CEP08127.1 - 0.15 12.1 0.1 0.15 12.1 0.0 3.3 4 0 0 4 4 4 0 YqfQ-like protein zf-CCCH_2 PF14608.1 CEP08127.1 - 9.8 6.3 8.7 0.12 12.3 0.3 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 CEP08128.1 - 4.5e-61 206.2 0.0 6.5e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08128.1 - 2.3e-34 118.6 0.0 3.3e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP08128.1 - 2.6e-07 29.9 0.2 4.5e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP08128.1 - 2.9e-05 23.9 2.0 0.0058 16.4 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP08128.1 - 4.9e-05 22.4 0.0 9.1e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CEP08128.1 - 0.0003 20.1 0.7 0.00049 19.5 0.5 1.3 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 CEP08128.1 - 0.019 14.3 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CEP08128.1 - 0.029 13.9 0.5 0.083 12.4 0.4 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase SRF-TF PF00319.13 CEP08129.1 - 1.9e-22 78.1 0.2 3.9e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prefoldin PF02996.12 CEP08130.1 - 5.9e-17 61.4 0.1 5.9e-17 61.4 0.1 2.2 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 CEP08130.1 - 7.1e-11 41.7 0.1 3.2e-10 39.6 0.1 2.2 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 CEP08130.1 - 7.9e-09 36.3 1.5 7.9e-09 36.3 1.0 7.6 5 3 2 7 7 7 3 Domain of unknown function (DUF3835) B56 PF01603.15 CEP08131.1 - 2.1e-170 566.7 6.6 2.7e-170 566.4 4.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Rap_GAP PF02145.10 CEP08133.1 - 7.1e-49 165.7 0.1 1.9e-48 164.3 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP zf-H2C2 PF09337.5 CEP08134.1 - 0.0003 20.1 1.0 0.0028 17.0 0.1 2.3 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger UvrD_C PF13361.1 CEP08135.1 - 1.8e-63 215.1 1.5 2e-63 214.9 0.1 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CEP08135.1 - 3.2e-21 75.9 1.6 2.8e-09 36.7 0.1 3.5 3 1 1 4 4 4 3 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CEP08135.1 - 3.3e-12 46.4 0.0 9e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CEP08135.1 - 3.7e-06 26.6 0.2 0.042 13.3 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 CEP08135.1 - 4.5e-06 26.1 0.3 0.011 15.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CEP08135.1 - 0.00011 21.9 0.0 0.029 14.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CEP08135.1 - 0.066 12.7 0.1 0.67 9.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2183 PF09949.4 CEP08136.1 - 2.6e-32 110.6 0.0 2.6e-32 110.6 0.0 2.9 3 1 1 4 4 4 1 Uncharacterized conserved protein (DUF2183) ATP-grasp_2 PF08442.5 CEP08136.1 - 0.0041 16.5 0.1 0.059 12.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain LNS2 PF08235.8 CEP08136.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Zea_mays_MuDR PF05928.6 CEP08136.1 - 0.025 13.9 0.3 0.025 13.9 0.2 1.6 2 0 0 2 2 2 0 Zea mays MURB-like protein (MuDR) Kinesin PF00225.18 CEP08137.1 - 6.6e-106 353.7 3.3 6.6e-106 353.7 2.3 2.5 2 1 0 3 3 3 1 Kinesin motor domain Tmemb_cc2 PF10267.4 CEP08137.1 - 0.00082 18.0 23.4 0.00082 18.0 16.2 2.3 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein IncA PF04156.9 CEP08137.1 - 5.1 6.6 38.3 0.25 10.9 8.3 3.7 2 1 0 3 3 3 0 IncA protein ADIP PF11559.3 CEP08137.1 - 6.5 6.6 48.7 0.52 10.2 7.7 3.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding tRNA-synt_2d PF01409.15 CEP08138.1 - 3.3e-89 298.3 0.0 4.5e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 CEP08138.1 - 1.1e-06 27.6 3.8 7.4e-05 21.6 0.1 3.4 3 1 0 4 4 4 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 CEP08138.1 - 7.4e-06 25.6 0.2 1.7e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) eIF-3_zeta PF05091.7 CEP08139.1 - 9.2e-170 565.6 1.2 1.1e-169 565.3 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF16 PF01519.11 CEP08139.1 - 0.016 15.3 0.2 4 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 mRNA_cap_enzyme PF01331.14 CEP08139.1 - 0.032 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Snapin_Pallidin PF14712.1 CEP08140.1 - 1.6e-14 53.9 0.2 1.8e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Snapin/Pallidin TMF_TATA_bd PF12325.3 CEP08140.1 - 0.0057 16.3 3.2 0.0074 16.0 2.2 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 CEP08140.1 - 0.039 13.8 0.1 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.5 CEP08140.1 - 0.092 12.4 0.6 0.15 11.7 0.4 1.3 1 1 0 1 1 1 0 Serine rich protein interaction domain Shikimate_DH PF01488.15 CEP08140.1 - 0.097 12.7 0.6 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Spc7 PF08317.6 CEP08140.1 - 0.14 10.7 2.9 0.15 10.6 2.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 CEP08140.1 - 0.19 11.5 7.4 0.66 9.8 0.3 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CEP08140.1 - 0.25 10.8 4.9 2.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Rnk_N PF14760.1 CEP08140.1 - 0.31 11.1 3.7 0.52 10.4 0.2 2.3 2 0 0 2 2 2 0 Rnk N-terminus Prefoldin PF02996.12 CEP08140.1 - 1.2 8.8 4.5 1.5 8.4 0.2 2.1 1 1 0 2 2 2 0 Prefoldin subunit FliT PF05400.8 CEP08140.1 - 1.9 8.9 5.6 3 8.2 3.1 1.8 1 1 1 2 2 2 0 Flagellar protein FliT GATA PF00320.22 CEP08141.1 - 8.1e-17 60.2 2.3 1.7e-16 59.2 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CEP08141.1 - 4.6e-15 54.8 2.1 1.8e-14 53.0 1.6 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) MCM PF00493.18 CEP08142.1 - 4.8e-136 452.9 0.0 7e-136 452.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CEP08142.1 - 4.8e-21 75.4 2.0 1.4e-20 73.9 0.7 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 CEP08142.1 - 4e-08 33.0 0.0 1.1e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CEP08142.1 - 1.2e-06 27.8 0.0 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEP08142.1 - 0.00029 20.4 0.0 0.024 14.2 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CEP08142.1 - 0.00043 19.8 0.0 2.1 7.7 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CEP08142.1 - 0.0083 16.1 0.0 0.069 13.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 CEP08142.1 - 0.17 11.8 2.2 2.1 8.3 0.0 3.4 3 2 2 5 5 5 0 AAA ATPase domain Aconitase PF00330.15 CEP08143.1 - 8.1e-177 588.3 0.1 2e-176 587.0 0.1 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEP08143.1 - 3.2e-43 146.9 0.0 6.3e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Pkinase PF00069.20 CEP08145.1 - 2.6e-55 187.3 0.0 5e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08145.1 - 9.3e-20 70.7 0.0 1.5e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP08145.1 - 2.3e-05 24.2 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP08145.1 - 5.9e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_A_type_inc PF04508.7 CEP08146.1 - 0.0067 16.1 1.3 0.02 14.6 0.9 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Peptidase_C12 PF01088.16 CEP08147.1 - 4.3e-49 166.5 0.2 6.3e-49 166.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF872 PF05915.7 CEP08148.1 - 5.9e-19 68.0 0.1 6.4e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Adeno_E3 PF06040.6 CEP08148.1 - 0.14 12.1 0.2 0.14 12.1 0.1 1.9 1 1 1 2 2 2 0 Adenovirus E3 protein DUF973 PF06157.6 CEP08148.1 - 0.29 10.0 4.7 0.35 9.8 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) YrhK PF14145.1 CEP08148.1 - 0.39 10.4 3.2 5.3 6.7 0.1 2.1 2 0 0 2 2 2 0 YrhK-like protein Pox_I5 PF04713.7 CEP08148.1 - 2.7 7.7 6.5 0.32 10.7 1.0 1.8 2 0 0 2 2 2 0 Poxvirus protein I5 Hep_59 PF07052.6 CEP08149.1 - 6.7e-30 103.5 0.5 6.7e-30 103.5 0.3 3.7 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF506 PF04720.7 CEP08149.1 - 8.5 5.9 10.4 2.2 7.8 2.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF506) DDE_3 PF13358.1 CEP08150.1 - 0.00043 20.0 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3336 PF11815.3 CEP08151.1 - 2.5e-27 95.1 6.9 5.9e-27 93.9 3.8 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CEP08151.1 - 4.6e-15 56.0 0.3 1.3e-14 54.6 0.0 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase F-box PF00646.28 CEP08152.1 - 0.0081 15.7 0.3 0.026 14.1 0.2 2.0 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 CEP08152.1 - 0.02 15.2 1.6 0.049 14.0 1.1 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.2 CEP08152.1 - 0.056 13.1 2.5 0.28 10.9 1.8 2.2 1 0 0 1 1 1 0 F-box-like DUF3020 PF11223.3 CEP08153.1 - 1.8e-19 69.8 13.5 1.8e-19 69.8 9.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) CAF-1_p150 PF11600.3 CEP08153.1 - 0.0032 16.9 14.2 0.0032 16.9 9.9 3.7 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1628 PF07790.6 CEP08153.1 - 0.027 15.2 1.3 0.081 13.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) ATG_C PF09333.6 CEP08154.1 - 1.4e-16 60.3 0.0 4.5e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain zf-CCHC PF00098.18 CEP08154.1 - 9.1e-11 41.1 19.7 0.0048 16.7 1.2 4.5 4 0 0 4 4 4 4 Zinc knuckle ATG2_CAD PF13329.1 CEP08154.1 - 2.1e-10 40.3 0.3 2.1e-10 40.3 0.2 3.6 4 0 0 4 4 4 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.2 CEP08154.1 - 5.4e-09 35.6 0.6 5.4e-09 35.6 0.4 3.4 3 1 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter zf-CCHC_2 PF13696.1 CEP08154.1 - 0.0031 16.9 12.2 0.37 10.3 0.3 3.8 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP08154.1 - 0.077 12.6 18.2 0.98 9.1 0.4 4.6 3 1 1 4 4 4 0 Zinc knuckle TIP49 PF06068.8 CEP08155.1 - 3.2e-191 635.3 1.3 3.7e-191 635.0 0.9 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CEP08155.1 - 8.8e-12 45.3 0.1 1.2e-06 28.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEP08155.1 - 1.3e-11 43.9 1.9 1.4e-06 27.5 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEP08155.1 - 5.7e-07 29.7 0.0 0.019 14.9 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CEP08155.1 - 1.8e-05 24.8 0.0 0.073 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CEP08155.1 - 0.0023 17.6 0.1 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CEP08155.1 - 0.0024 17.0 0.1 0.073 12.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CEP08155.1 - 0.0029 17.2 0.0 0.0068 16.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CEP08155.1 - 0.0033 17.7 0.0 0.018 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEP08155.1 - 0.0034 16.7 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CEP08155.1 - 0.0066 15.9 0.1 3.3 7.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.1 CEP08155.1 - 0.014 15.2 0.0 0.47 10.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 CEP08155.1 - 0.018 14.8 1.0 0.48 10.2 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CEP08155.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CEP08155.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CEP08155.1 - 0.033 13.6 0.1 0.07 12.5 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CEP08155.1 - 0.044 12.8 0.1 0.1 11.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 CEP08155.1 - 0.049 14.4 0.1 0.14 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CEP08155.1 - 0.073 12.2 0.1 0.24 10.5 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CEP08155.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Reticulon PF02453.12 CEP08156.1 - 5e-18 65.2 6.3 7.6e-18 64.6 4.4 1.3 1 0 0 1 1 1 1 Reticulon SPC22 PF04573.7 CEP08157.1 - 1.7e-40 138.1 2.9 2e-40 137.8 2.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Sel1 PF08238.7 CEP08158.1 - 5.8e-30 103.0 74.3 0.0045 17.5 0.0 22.0 24 0 0 24 24 24 11 Sel1 repeat PPR_3 PF13812.1 CEP08158.1 - 0.079 13.2 0.2 14 6.2 0.0 4.8 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Pkinase PF00069.20 CEP08159.1 - 6.4e-37 127.1 0.0 8.6e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08159.1 - 9.6e-14 51.0 0.0 4.2e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CEP08159.1 - 0.0034 17.1 0.1 0.007 16.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP08159.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Vps5 PF09325.5 CEP08160.1 - 2.7e-74 249.3 16.3 2.7e-74 249.3 11.3 1.8 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 CEP08160.1 - 6.1e-25 87.2 0.3 9.4e-23 80.1 0.0 2.7 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 CEP08160.1 - 0.00026 20.3 7.6 0.044 13.0 5.3 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF3437 PF11919.3 CEP08160.1 - 0.057 13.1 0.6 0.19 11.4 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Glutaredoxin2_C PF04399.8 CEP08160.1 - 1 8.9 7.8 1.1 8.8 1.4 3.2 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain PIG-F PF06699.6 CEP08161.1 - 3.7e-39 134.6 12.8 4.4e-39 134.4 8.9 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF3082 PF11282.3 CEP08161.1 - 0.0071 16.3 6.7 0.0087 16.1 0.5 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3082) MerE PF05052.7 CEP08161.1 - 0.26 11.2 2.5 0.79 9.7 1.7 1.9 1 0 0 1 1 1 0 MerE protein DUF2530 PF10745.4 CEP08161.1 - 1.1 9.2 4.6 0.73 9.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF2975 PF11188.3 CEP08161.1 - 1.6 8.4 6.9 0.15 11.7 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Ada3 PF10198.4 CEP08162.1 - 2.3e-33 114.7 3.2 2.3e-33 114.7 2.2 2.2 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Herpes_UL56 PF04534.7 CEP08162.1 - 4.3 6.9 7.4 39 3.8 0.0 2.8 2 1 1 3 3 3 0 Herpesvirus UL56 protein MCPVI PF02993.9 CEP08162.1 - 5.2 7.1 7.3 2.2 8.3 3.1 1.7 2 0 0 2 2 2 0 Minor capsid protein VI Cgr1 PF03879.9 CEP08163.1 - 2.2e-18 66.4 29.3 2.7e-18 66.1 20.3 1.1 1 0 0 1 1 1 1 Cgr1 family Vfa1 PF08432.5 CEP08163.1 - 0.21 11.5 16.5 0.25 11.3 11.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 IncA PF04156.9 CEP08163.1 - 0.37 10.3 5.9 0.48 9.9 4.1 1.3 1 0 0 1 1 1 0 IncA protein DUF3340 PF11818.3 CEP08163.1 - 1.3 8.9 14.5 1.9 8.4 10.0 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DDHD PF02862.12 CEP08163.1 - 2.9 7.6 6.2 3.3 7.4 4.3 1.1 1 0 0 1 1 1 0 DDHD domain RapA_C PF12137.3 CEP08163.1 - 5.3 5.7 11.2 6.3 5.5 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal HLH PF00010.21 CEP08164.1 - 1.5e-12 47.0 1.9 1.5e-12 47.0 1.3 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Myc-LZ PF02344.10 CEP08164.1 - 0.0052 16.3 2.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 2 Myc leucine zipper domain Acetyltransf_2 PF00797.12 CEP08164.1 - 0.25 10.8 3.0 0.46 10.0 2.1 1.3 1 0 0 1 1 1 0 N-acetyltransferase Virulence_fact PF13769.1 CEP08164.1 - 1.6 8.6 5.1 2.5 8.0 1.4 2.3 2 0 0 2 2 2 0 Virulence factor REC114-like PF15165.1 CEP08164.1 - 4.4 6.9 11.8 0.33 10.6 4.1 1.8 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like GTP_EFTU PF00009.22 CEP08165.1 - 3.3e-43 147.3 0.0 5e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CEP08165.1 - 1.6e-26 92.2 0.0 9.9e-26 89.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CEP08165.1 - 5.2e-22 77.5 0.0 2.3e-21 75.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CEP08165.1 - 7.2e-10 38.8 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CEP08165.1 - 8.5e-07 28.7 0.0 2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 CEP08165.1 - 2.1e-06 28.2 0.1 5.9e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEP08165.1 - 6.3e-05 22.9 0.4 0.00015 21.6 0.2 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 CEP08165.1 - 0.02 14.2 0.3 0.086 12.2 0.2 2.0 1 1 0 1 1 1 0 Ras family Septin PF00735.13 CEP08165.1 - 0.026 13.5 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.18 CEP08165.1 - 0.031 14.0 0.3 0.55 10.0 0.0 2.4 1 1 1 2 2 2 0 Dynamin family F-box PF00646.28 CEP08166.1 - 1.4e-05 24.6 0.0 3.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEP08166.1 - 0.00058 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 CEP08167.1 - 1.1e-05 25.1 0.0 3.2e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP08167.1 - 5.5e-05 22.7 0.0 0.00016 21.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain Tubulin PF00091.20 CEP08168.1 - 2.7e-72 243.1 0.0 4.2e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEP08168.1 - 3.3e-48 162.8 0.0 5.2e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CEP08168.1 - 1.3e-06 28.4 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Pkinase PF00069.20 CEP08169.1 - 1.1e-68 231.1 0.0 1.4e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08169.1 - 1.1e-34 119.7 0.0 1.4e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP08169.1 - 7.9e-06 25.0 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ARS2 PF04959.8 CEP08169.1 - 0.2 11.8 0.8 0.33 11.0 0.6 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 WCCH PF03716.9 CEP08170.1 - 0.0035 16.7 0.6 0.0076 15.6 0.4 1.6 1 0 0 1 1 1 1 WCCH motif PAPA-1 PF04795.7 CEP08171.1 - 1.9e-18 66.9 6.8 1.9e-18 66.9 4.7 2.5 3 1 1 4 4 4 1 PAPA-1-like conserved region zf-HIT PF04438.11 CEP08171.1 - 0.2 11.3 1.8 0.28 10.8 1.2 1.2 1 0 0 1 1 1 0 HIT zinc finger HECT PF00632.20 CEP08172.1 - 1e-86 290.9 0.1 1e-86 290.9 0.1 2.4 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Pkinase_Tyr PF07714.12 CEP08173.1 - 7.4e-15 54.7 0.0 1.2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CEP08173.1 - 2.4e-14 53.1 0.0 4.9e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain DUF4378 PF14309.1 CEP08173.1 - 0.079 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) CENP-I PF07778.6 CEP08174.1 - 2.8e-51 174.2 20.7 4.5e-49 166.9 14.4 2.1 1 1 0 1 1 1 1 Mis6 DUF2177 PF09945.4 CEP08174.1 - 0.07 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) EMP24_GP25L PF01105.19 CEP08175.1 - 2e-47 161.3 1.8 2e-47 161.3 1.2 1.5 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD NUDIX PF00293.23 CEP08176.1 - 1.7e-12 47.0 0.1 2.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUC129 PF08157.6 CEP08176.1 - 0.14 12.1 0.2 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 NUC129 domain DNA_pol_B PF00136.16 CEP08177.1 - 3.7e-105 352.4 0.7 1.6e-104 350.2 0.5 2.0 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CEP08177.1 - 7.4e-26 90.7 0.0 1.9e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 CEP08177.1 - 1.8e-16 60.0 11.4 1.8e-16 60.0 7.9 2.4 2 1 0 2 2 2 1 DNA Polymerase alpha zinc finger Chitin_synth_2 PF03142.10 CEP08179.1 - 2.9e-230 765.1 2.9 4.5e-230 764.5 2.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEP08179.1 - 6.3e-141 470.7 7.0 7.9e-141 470.3 4.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 CEP08179.1 - 7.3e-22 76.9 0.3 1.5e-15 56.7 0.1 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CEP08179.1 - 1.4e-17 64.3 0.0 7.7e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEP08179.1 - 5.6e-14 52.2 4.8 5.6e-14 52.2 3.3 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CEP08179.1 - 6.1e-05 22.7 0.0 0.0041 16.8 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP08179.1 - 0.00012 21.4 0.4 0.0012 18.1 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 21 DUF2443 PF10398.4 CEP08179.1 - 0.02 14.7 0.0 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) PhoH PF02562.11 CEP08179.1 - 0.02 14.0 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein G_glu_transpept PF01019.16 CEP08180.1 - 2.1e-170 567.5 0.0 2.4e-170 567.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Nop PF01798.13 CEP08181.1 - 2.5e-60 202.1 0.0 5.2e-60 201.1 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CEP08181.1 - 2.1e-26 91.4 1.4 3.9e-26 90.6 1.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CEP08181.1 - 1.4e-24 86.0 1.3 1.4e-24 86.0 0.9 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 CEP08181.1 - 0.4 10.3 29.4 0.65 9.6 20.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.4 CEP08181.1 - 1.8 8.2 22.1 4.9 6.7 15.3 1.8 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ribosomal_L11_N PF03946.9 CEP08182.1 - 2.7e-18 65.1 0.1 4.6e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CEP08182.1 - 7.5e-12 45.2 0.1 1.3e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain tRNA-synt_2b PF00587.20 CEP08184.1 - 1.1e-27 96.7 0.0 4.7e-27 94.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CEP08184.1 - 4.5e-13 49.1 3.4 9.4e-13 48.1 2.4 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain EamA PF00892.15 CEP08185.1 - 3.3e-06 27.1 15.1 3.4e-06 27.1 8.0 2.5 2 1 0 2 2 2 1 EamA-like transporter family UPF0542 PF15086.1 CEP08185.1 - 0.019 14.6 1.0 0.6 9.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Rhomboid_SP PF12595.3 CEP08185.1 - 0.19 11.3 2.4 0.28 10.7 1.7 1.2 1 0 0 1 1 1 0 Rhomboid serine protease EmrE PF13536.1 CEP08185.1 - 0.61 10.3 13.6 0.051 13.7 5.9 1.9 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DUF2340 PF10209.4 CEP08186.1 - 1.8e-41 141.1 1.5 2.1e-41 140.9 1.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) CDO_I PF05995.7 CEP08186.1 - 0.071 12.2 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I NDT80_PhoG PF05224.7 CEP08187.1 - 7.4e-36 123.8 0.0 7.4e-36 123.8 0.0 3.4 3 2 0 3 3 3 1 NDT80 / PhoG like DNA-binding family TFR_dimer PF04253.10 CEP08188.1 - 1.1e-16 60.5 0.6 3.1e-16 59.0 0.1 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 CEP08188.1 - 2.8e-12 46.7 0.1 6.1e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CEP08188.1 - 0.0002 20.9 0.1 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 PA domain XPG_N PF00752.12 CEP08189.1 - 3.1e-38 130.1 0.1 7.4e-38 128.8 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 CEP08189.1 - 8.3e-30 102.7 0.1 2.7e-29 101.0 0.0 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 CEP08189.1 - 5.9e-05 23.2 1.5 0.00012 22.2 0.0 2.3 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 CEP08189.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif F-box-like PF12937.2 CEP08190.1 - 1.2e-05 24.9 0.1 2.7e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP08190.1 - 0.00078 19.0 0.3 0.0022 17.5 0.2 1.8 1 0 0 1 1 1 1 F-box domain PSP1 PF04468.7 CEP08190.1 - 0.069 13.1 0.2 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 PSP1 C-terminal conserved region ABC_membrane PF00664.18 CEP08191.1 - 1.4e-43 149.2 35.6 9.7e-23 80.9 10.3 3.8 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP08191.1 - 1.1e-32 113.1 0.0 4.3e-17 62.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CEP08191.1 - 1.1e-07 31.3 0.3 0.00061 19.0 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CEP08191.1 - 0.0072 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CEP08191.1 - 0.054 13.4 0.7 0.73 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 CEP08191.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEP08191.1 - 0.14 12.2 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CEP08191.1 - 0.17 11.3 0.1 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 CEP08191.1 - 0.21 10.5 0.1 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sel1 PF08238.7 CEP08192.1 - 9e-134 433.0 56.3 2.2e-12 47.1 0.1 16.1 16 0 0 16 16 16 16 Sel1 repeat TPR_6 PF13174.1 CEP08192.1 - 2e-05 24.7 10.6 1.3 9.6 0.1 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP08192.1 - 0.0028 17.7 13.7 37 4.8 0.2 9.0 9 1 1 10 10 10 1 Tetratricopeptide repeat PDCD2_C PF04194.8 CEP08194.1 - 5.9e-30 104.0 1.2 5.9e-30 104.0 0.8 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.13 CEP08194.1 - 3e-05 23.7 10.9 3e-05 23.7 7.6 3.3 4 1 0 4 4 4 1 MYND finger zf-Mss51 PF13824.1 CEP08194.1 - 0.41 10.5 7.8 0.3 10.9 3.3 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Kelch_4 PF13418.1 CEP08195.1 - 7.7e-44 147.2 5.8 5.6e-10 38.8 0.0 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP08195.1 - 4e-38 128.7 22.5 3.3e-07 30.2 0.0 8.6 9 1 0 9 9 9 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP08195.1 - 4.6e-37 125.4 6.8 2.2e-07 30.6 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 CEP08195.1 - 1.3e-36 123.9 1.0 1.4e-05 24.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CEP08195.1 - 2.6e-34 115.9 4.5 8.4e-06 25.7 0.0 6.7 3 1 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 CEP08195.1 - 5.9e-33 111.4 6.5 1.4e-05 24.6 0.1 6.5 6 0 0 6 6 6 6 Kelch motif TATR PF03430.8 CEP08195.1 - 7 5.1 7.6 9.7 4.6 5.2 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator TLD PF07534.11 CEP08196.1 - 1.3e-28 99.7 0.8 2.6e-28 98.7 0.5 1.5 1 0 0 1 1 1 1 TLD Lipase_GDSL PF00657.17 CEP08197.1 - 6.1e-08 32.7 0.1 3.8e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP08197.1 - 0.0016 18.6 0.2 0.0048 17.0 0.2 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ISK_Channel PF02060.10 CEP08198.1 - 0.051 13.1 0.3 0.09 12.3 0.2 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Sec5 PF15469.1 CEP08200.1 - 6.5e-54 182.4 1.8 6.5e-54 182.4 1.2 3.4 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 CEP08200.1 - 5.9e-07 29.2 0.9 5.9e-07 29.2 0.6 3.6 3 0 0 3 3 3 1 Vps51/Vps67 Fib_alpha PF08702.5 CEP08200.1 - 6.1 6.9 17.4 0.15 12.1 0.8 4.3 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF4203 PF13886.1 CEP08201.1 - 1.5e-15 57.2 37.8 1.8e-15 56.9 26.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Zn_clus PF00172.13 CEP08202.1 - 0.00016 21.4 11.2 0.00016 21.4 7.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 CEP08202.1 - 0.00053 19.7 0.0 0.0015 18.2 0.0 1.8 2 0 0 2 2 2 1 PAS fold Toxin_60 PF15607.1 CEP08202.1 - 0.035 14.1 1.9 0.041 13.9 0.1 1.9 2 0 0 2 2 2 0 Putative toxin 60 Apc3 PF12895.2 CEP08203.1 - 1.1e-17 63.9 18.8 2.3e-12 46.8 1.4 4.6 4 1 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CEP08203.1 - 3.4e-16 58.6 17.3 2.2e-07 30.4 0.1 5.9 4 2 1 6 6 6 4 TPR repeat TPR_19 PF14559.1 CEP08203.1 - 2.2e-13 50.3 4.1 0.002 18.4 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP08203.1 - 4.8e-13 48.8 6.6 3.5e-05 23.6 0.2 6.6 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 CEP08203.1 - 9.2e-13 47.0 14.7 0.0049 16.6 0.0 8.5 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP08203.1 - 3.3e-12 45.4 10.4 0.0021 17.5 0.0 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEP08203.1 - 4.4e-12 44.8 12.3 0.0012 18.5 0.4 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP08203.1 - 1.3e-11 44.0 0.3 0.0062 17.0 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEP08203.1 - 1.6e-06 27.8 12.2 0.24 11.6 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP08203.1 - 2.2e-05 24.6 2.2 0.11 12.9 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP08203.1 - 3.8e-05 23.1 3.9 8.5 6.4 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP08203.1 - 0.00026 21.5 2.3 0.43 11.3 0.0 4.6 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 CEP08203.1 - 0.0014 18.3 5.7 0.013 15.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEP08203.1 - 0.0025 17.6 2.5 4.3 7.3 0.0 4.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 CEP08203.1 - 0.06 13.2 2.6 64 3.6 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat EamA PF00892.15 CEP08204.1 - 0.00013 21.9 35.9 0.00029 20.8 3.4 3.3 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 CEP08204.1 - 0.00055 19.6 28.9 0.01 15.5 6.8 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CEP08204.1 - 0.0015 18.7 9.1 0.0015 18.7 6.3 4.1 2 2 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CEP08204.1 - 0.14 11.2 10.4 0.41 9.6 7.2 1.8 1 1 0 1 1 1 0 Nucleotide-sugar transporter DUF4260 PF14079.1 CEP08204.1 - 6 6.7 11.6 0.26 11.1 3.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4260) MFS_1 PF07690.11 CEP08205.1 - 2.8e-22 78.9 58.3 3e-22 78.8 36.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CEP08205.1 - 2.5e-09 35.8 26.1 4.1e-09 35.1 18.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phosphoesterase PF04185.9 CEP08206.1 - 3.2e-30 105.5 9.4 1.7e-27 96.5 1.6 2.9 2 1 1 3 3 3 3 Phosphoesterase family Qn_am_d_aII PF14930.1 CEP08206.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Ribosomal_S8 PF00410.14 CEP08208.1 - 3.8e-27 94.6 0.0 4.5e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Pescadillo_N PF06732.6 CEP08209.1 - 6.5e-123 409.4 3.5 6.5e-123 409.4 2.4 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CEP08209.1 - 1.7e-11 44.0 0.0 7.3e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Mid1 PF12929.2 CEP08210.1 - 1.1e-88 297.8 15.5 6.1e-88 295.3 10.8 1.9 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 CEP08210.1 - 0.00046 20.5 2.1 0.13 12.6 0.3 2.7 2 0 0 2 2 2 2 Fz domain Actin PF00022.14 CEP08211.1 - 3.2e-138 460.4 0.0 3.7e-138 460.2 0.0 1.0 1 0 0 1 1 1 1 Actin EzrA PF06160.7 CEP08212.1 - 0.00025 19.3 0.9 0.00025 19.3 0.6 1.6 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA IFT57 PF10498.4 CEP08212.1 - 0.32 9.6 8.2 0.017 13.8 1.5 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MscS_porin PF12795.2 CEP08212.1 - 1.3 8.2 11.2 0.067 12.5 3.9 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain BTD PF09270.5 CEP08215.1 - 7.6e-26 90.7 0.3 3.3e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 CEP08215.1 - 5.2e-21 75.5 8.8 5.9e-19 68.9 4.0 2.8 2 1 0 2 2 2 1 LAG1, DNA binding TSA PF03249.8 CEP08215.1 - 0.22 10.0 6.4 0.35 9.3 4.4 1.2 1 0 0 1 1 1 0 Type specific antigen Sec7 PF01369.15 CEP08216.1 - 3.2e-24 85.6 0.3 4.5e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain Sugar_tr PF00083.19 CEP08218.1 - 2.6e-93 313.0 20.2 3.1e-93 312.8 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP08218.1 - 2.5e-30 105.4 30.4 3.8e-21 75.1 3.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CEP08218.1 - 0.00015 20.1 4.5 0.00028 19.2 3.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.7 CEP08218.1 - 0.00089 18.4 3.8 0.0027 16.8 2.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF554) Folate_carrier PF01770.13 CEP08218.1 - 0.023 13.2 3.6 0.98 7.8 0.5 2.3 2 0 0 2 2 2 0 Reduced folate carrier DUF1228 PF06779.9 CEP08218.1 - 0.036 14.1 14.3 0.11 12.5 0.5 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) RRM_1 PF00076.17 CEP08219.1 - 2.1e-31 107.3 5.0 3e-15 55.6 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP08219.1 - 1.8e-26 91.9 0.1 6.7e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP08219.1 - 1.3e-11 44.1 0.0 2e-05 24.3 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CEP08219.1 - 0.13 11.8 0.1 4.5 6.8 0.0 2.9 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF1675 PF07897.6 CEP08219.1 - 0.94 9.2 20.5 1.8 8.3 14.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PLRV_ORF5 PF01690.12 CEP08219.1 - 6.6 5.7 21.6 9.6 5.2 15.0 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Cullin PF00888.17 CEP08220.1 - 2.3e-147 492.0 21.8 3.1e-147 491.6 15.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CEP08220.1 - 8.6e-28 95.9 4.6 8.6e-28 95.9 3.2 2.6 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF1834 PF08873.6 CEP08220.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) A_deaminase PF00962.17 CEP08221.1 - 7.2e-113 376.8 0.0 1e-112 376.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Clathrin PF00637.15 CEP08221.1 - 0.047 13.2 1.8 2.2 7.8 0.0 2.6 1 1 1 2 2 2 0 Region in Clathrin and VPS NAD_binding_10 PF13460.1 CEP08222.1 - 8.3e-21 74.8 0.0 1.2e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEP08222.1 - 2.1e-14 53.3 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CEP08222.1 - 7e-12 45.2 0.1 2.2e-11 43.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEP08222.1 - 7.1e-12 44.6 0.4 1.5e-11 43.5 0.2 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CEP08222.1 - 8.6e-10 37.9 0.0 0.00072 18.5 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 CEP08222.1 - 6.9e-07 28.5 0.1 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 CEP08222.1 - 2e-06 26.9 0.2 0.0035 16.2 0.1 2.7 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 CEP08222.1 - 0.0005 20.0 0.1 0.0026 17.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CEP08222.1 - 0.0047 15.8 0.0 0.0081 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 CEP08222.1 - 0.014 15.2 0.0 0.057 13.2 0.0 1.9 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.15 CEP08222.1 - 0.046 13.6 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SERTA PF06031.8 CEP08223.1 - 0.012 14.9 0.2 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 SERTA motif Nro1 PF12753.2 CEP08223.1 - 0.04 12.8 7.7 0.046 12.6 5.4 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 SDA1 PF05285.7 CEP08223.1 - 7.6 5.7 10.4 9.4 5.4 7.2 1.1 1 0 0 1 1 1 0 SDA1 zf-A20 PF01754.11 CEP08224.1 - 1.4e-08 34.1 8.6 3.6e-08 32.8 6.0 1.7 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 CEP08224.1 - 4.9e-08 32.7 11.3 4.9e-08 32.7 7.8 2.0 2 0 0 2 2 2 1 AN1-like Zinc finger Myticin-prepro PF10690.4 CEP08224.1 - 3.7 7.6 7.5 4.3 7.4 0.8 2.3 2 1 0 2 2 2 0 Myticin pre-proprotein from the mussel Cyclin PF08613.6 CEP08225.1 - 1.1e-19 71.3 0.4 1.1e-19 71.3 0.3 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CEP08225.1 - 2.8e-06 26.9 1.2 1.8e-05 24.2 0.0 2.6 3 0 0 3 3 3 1 Cyclin, N-terminal domain MCR_alpha PF02249.12 CEP08225.1 - 0.037 14.0 0.1 0.075 13.0 0.1 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain TraK PF06586.6 CEP08225.1 - 0.038 13.1 0.2 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 TraK protein SNARE PF05739.14 CEP08226.1 - 1.6e-17 62.9 12.3 4e-17 61.6 4.4 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CEP08226.1 - 1.6e-11 44.2 1.2 1.6e-11 44.2 0.8 3.4 2 2 1 3 3 3 1 Syntaxin DUF4094 PF13334.1 CEP08226.1 - 0.0057 17.0 1.1 0.0057 17.0 0.7 3.5 2 2 1 3 3 3 1 Domain of unknown function (DUF4094) Ldh_1_C PF02866.13 CEP08226.1 - 0.0065 16.2 0.2 0.0065 16.2 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain VitD-bind_III PF09164.5 CEP08226.1 - 0.068 12.7 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Flu_NS2 PF00601.14 CEP08226.1 - 0.12 12.5 2.7 0.77 10.0 0.1 2.5 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) FAM178 PF14816.1 CEP08227.1 - 2e-06 26.7 0.7 2e-06 26.7 0.5 2.2 1 1 0 2 2 2 1 Family of unknown function, FAM178 Coagulin PF02035.10 CEP08227.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Coagulin Ras PF00071.17 CEP08228.1 - 3.6e-45 153.2 0.1 4.7e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP08228.1 - 3.8e-19 69.3 0.2 8.3e-19 68.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP08228.1 - 8e-12 44.7 0.1 9.9e-12 44.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP08228.1 - 4.8e-09 35.6 0.1 6.8e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP08228.1 - 6e-05 22.5 0.2 0.0012 18.2 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP08228.1 - 0.0011 18.8 0.4 0.0018 18.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CEP08228.1 - 0.0039 16.7 0.0 0.37 10.2 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 CEP08228.1 - 0.0053 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 CEP08228.1 - 0.0081 15.4 0.7 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CEP08228.1 - 0.0082 16.1 0.3 0.12 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 CEP08228.1 - 0.016 14.7 0.1 0.47 9.9 0.0 2.6 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CEP08228.1 - 0.036 13.4 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain DUF815 PF05673.8 CEP08228.1 - 0.044 12.6 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 CEP08228.1 - 0.049 13.7 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_S15 PF00312.17 CEP08228.1 - 0.051 13.3 0.4 0.094 12.4 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S15 AIG1 PF04548.11 CEP08228.1 - 0.056 12.5 1.2 1.1 8.3 0.2 2.1 2 0 0 2 2 2 0 AIG1 family AAA PF00004.24 CEP08228.1 - 0.12 12.5 0.0 0.5 10.5 0.0 2.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 CEP08228.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 BCS1_N PF08740.6 CEP08229.1 - 7.1e-56 188.7 0.5 1.1e-55 188.1 0.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CEP08229.1 - 5.2e-20 71.9 0.0 9.9e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SPRY PF00622.23 CEP08229.1 - 8.1e-18 64.6 0.4 1.4e-17 63.8 0.3 1.4 1 0 0 1 1 1 1 SPRY domain AAA_17 PF13207.1 CEP08229.1 - 1.6e-05 25.7 0.0 3.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP08229.1 - 0.00052 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP08229.1 - 0.00054 19.9 0.0 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 CEP08229.1 - 0.00062 18.7 0.0 0.0018 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 CEP08229.1 - 0.00075 19.5 0.2 0.0013 18.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CEP08229.1 - 0.0032 16.8 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP08229.1 - 0.0035 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP08229.1 - 0.0037 17.4 0.0 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEP08229.1 - 0.0061 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 CEP08229.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 CEP08229.1 - 0.025 13.6 0.0 0.063 12.3 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 CEP08229.1 - 0.03 14.0 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CEP08229.1 - 0.031 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.7 CEP08229.1 - 0.039 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF4341 PF14241.1 CEP08229.1 - 0.066 12.9 0.4 0.2 11.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4341) MMR_HSR1 PF01926.18 CEP08229.1 - 0.092 12.7 0.0 0.48 10.3 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 CEP08229.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CEP08229.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 CEP08229.1 - 0.17 12.3 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_19 PF13245.1 CEP08229.1 - 0.18 11.5 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 CEP08229.1 - 0.19 10.6 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain UTP15_C PF09384.5 CEP08230.1 - 1.4e-45 154.6 1.3 2.6e-45 153.7 0.9 1.5 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CEP08230.1 - 5.3e-28 95.8 7.8 4.9e-08 32.5 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CEP08230.1 - 3.9e-05 23.4 0.1 0.14 11.9 0.0 3.0 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region ECH PF00378.15 CEP08231.1 - 7e-51 172.7 0.1 9.5e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-UBR PF02207.15 CEP08232.1 - 2.1e-18 65.7 11.8 2.1e-18 65.7 8.2 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CEP08232.1 - 1.4e-10 40.7 2.2 1.8e-10 40.3 0.1 2.2 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS DUF1764 PF08576.5 CEP08233.1 - 4.7e-14 53.0 1.8 4.7e-14 53.0 1.2 3.1 1 1 2 3 3 3 2 Eukaryotic protein of unknown function (DUF1764) UxaC PF02614.9 CEP08233.1 - 0.3 9.6 6.0 0.091 11.3 0.3 1.9 1 1 1 2 2 2 0 Glucuronate isomerase Tfb4 PF03850.9 CEP08233.1 - 0.43 9.7 2.9 0.55 9.4 2.0 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 PBP_sp32 PF07222.7 CEP08233.1 - 2.9 7.0 10.6 4.2 6.4 7.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1770 PF08589.5 CEP08233.1 - 7.8 7.1 11.7 22 5.7 8.1 1.8 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) DUF4316 PF14195.1 CEP08233.1 - 7.8 6.6 14.2 0.31 11.1 5.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) MFS_1 PF07690.11 CEP08234.1 - 4.3e-36 124.3 30.6 1.6e-35 122.4 21.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2964 PF11177.3 CEP08234.1 - 0.18 11.7 10.4 17 5.4 0.3 4.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2964) Neurensin PF14927.1 CEP08234.1 - 2 7.7 5.4 22 4.4 0.5 3.3 3 0 0 3 3 3 0 Neurensin Transgly_assoc PF04226.8 CEP08234.1 - 2.3 8.3 9.4 8.8 6.4 0.5 2.9 2 0 0 2 2 2 0 Transglycosylase associated protein MMS1_N PF10433.4 CEP08235.1 - 9.4e-54 182.3 3.0 2.4e-53 181.0 2.1 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 CEP08235.1 - 3.4e-19 69.0 0.0 1e-18 67.5 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region WD40 PF00400.27 CEP08236.1 - 1.6e-90 294.0 32.2 1.8e-10 40.3 0.1 11.5 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 CEP08236.1 - 1.5e-45 154.3 0.1 2.6e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CEP08236.1 - 3.4e-06 25.4 20.7 0.46 8.5 0.0 8.1 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CEP08236.1 - 4.1e-05 22.5 8.4 0.12 11.1 0.2 5.2 3 1 2 5 5 5 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 CEP08236.1 - 0.00024 19.5 3.3 0.00081 17.7 0.2 3.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain SdiA-regulated PF06977.6 CEP08236.1 - 0.0023 16.9 0.2 0.007 15.3 0.2 1.9 1 0 0 1 1 1 1 SdiA-regulated Utp12 PF04003.7 CEP08236.1 - 0.018 14.9 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family Arylsulfotran_2 PF14269.1 CEP08237.1 - 0.12 11.5 0.7 0.13 11.3 0.5 1.1 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) OmpH PF03938.9 CEP08237.1 - 0.15 11.9 7.5 0.35 10.7 5.2 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0449 PF15136.1 CEP08237.1 - 0.24 11.6 4.1 0.7 10.1 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 APG6 PF04111.7 CEP08237.1 - 0.33 9.9 12.5 0.67 8.9 8.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 LLC1 PF14945.1 CEP08237.1 - 0.44 10.8 4.7 4.4 7.6 0.2 2.1 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein NTR2 PF15458.1 CEP08237.1 - 2 7.5 12.0 4.2 6.5 1.2 2.0 1 1 1 2 2 2 0 Nineteen complex-related protein 2 DUF4140 PF13600.1 CEP08237.1 - 4 7.9 7.8 5.8 7.4 0.4 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pho88 PF10032.4 CEP08238.1 - 6.5e-46 155.9 0.1 1e-45 155.3 0.1 1.3 1 0 0 1 1 1 1 Phosphate transport (Pho88) WD40 PF00400.27 CEP08238.1 - 3.2e-42 140.9 10.5 3.1e-09 36.3 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CEP08238.1 - 2.1e-10 40.6 0.9 7.1e-05 22.6 0.2 3.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CEP08238.1 - 0.0056 16.3 0.1 0.26 10.9 0.0 2.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CEP08238.1 - 0.0071 14.6 0.3 0.38 8.9 0.1 2.2 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF3312 PF11768.3 CEP08238.1 - 0.083 11.0 0.0 0.42 8.7 0.0 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) Alk_phosphatase PF00245.15 CEP08239.1 - 2.4e-57 194.5 1.2 1.4e-56 192.0 0.8 1.8 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 CEP08239.1 - 2.6e-05 23.5 4.2 9.9e-05 21.6 0.2 2.9 3 1 0 3 3 3 1 Sulfatase Phosphodiest PF01663.17 CEP08239.1 - 0.00053 19.4 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HSP70 PF00012.15 CEP08240.1 - 2.9e-273 907.2 8.2 3.3e-273 907.1 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP08240.1 - 6.3e-17 61.1 0.1 8.3e-16 57.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CEP08240.1 - 0.0041 16.2 0.1 0.03 13.4 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CEP08240.1 - 0.008 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CK2S PF15011.1 CEP08240.1 - 0.035 13.8 0.3 0.28 10.9 0.1 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate StbA PF06406.6 CEP08240.1 - 0.037 12.9 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein Sigma70_ner PF04546.8 CEP08241.1 - 0.042 13.4 11.4 0.055 13.0 7.3 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 CEP08241.1 - 0.15 11.5 10.7 0.23 10.9 7.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 CEP08241.1 - 0.43 9.6 8.4 2.3 7.2 6.8 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.1 CEP08241.1 - 0.73 10.1 13.2 1 9.7 9.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 CEP08241.1 - 1.4 8.1 12.8 1.7 7.8 8.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 CEP08241.1 - 2.9 6.5 20.6 3.9 6.0 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 CEP08241.1 - 4.9 5.0 8.3 5.7 4.8 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 CEP08241.1 - 5 6.9 10.0 8.2 6.2 7.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal MFS_1 PF07690.11 CEP08244.1 - 9.5e-39 133.0 25.5 9.5e-39 133.0 17.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 CEP08244.1 - 1.2 9.1 13.0 0.094 12.7 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) BolA PF01722.13 CEP08245.1 - 1.6e-17 63.1 0.0 2.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein DUF2415 PF10313.4 CEP08246.1 - 4.3e-10 39.1 0.0 3e-09 36.3 0.0 2.4 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 CEP08246.1 - 4.8e-07 29.4 0.0 0.062 13.2 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Lgl_C PF08596.5 CEP08246.1 - 0.0052 15.2 0.0 0.0084 14.6 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Coatomer_WDAD PF04053.9 CEP08246.1 - 0.01 14.6 0.0 0.02 13.6 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Peripla_BP_1 PF00532.16 CEP08246.1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PglZ PF08665.7 CEP08246.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 PglZ domain Cas_Cmr5 PF09701.5 CEP08249.1 - 0.025 14.7 0.1 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) TT_ORF1 PF02956.9 CEP08252.1 - 0.04 12.3 9.4 0.049 12.0 6.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 PMSI1 PF15322.1 CEP08252.1 - 0.34 9.9 11.2 0.41 9.7 7.8 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative ABC2_membrane_3 PF12698.2 CEP08252.1 - 5 6.0 6.6 5.4 5.9 4.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Suc_Fer-like PF06999.7 CEP08252.1 - 5.8 6.8 6.9 7.4 6.5 4.8 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like WD40 PF00400.27 CEP08254.1 - 1.5e-30 103.9 7.5 8.4e-12 44.4 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEP08254.1 - 0.0026 16.5 4.1 0.1 11.3 0.9 2.7 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 CEP08254.1 - 0.0067 14.6 0.1 0.01 14.0 0.1 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 NDUFB10 PF10249.4 CEP08255.1 - 2.2e-11 44.0 0.7 2.6e-11 43.7 0.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 SecA_SW PF07516.8 CEP08255.1 - 0.065 12.9 0.2 0.07 12.8 0.1 1.1 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Antimicrobial_6 PF08036.6 CEP08255.1 - 0.2 11.4 0.5 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide Alpha_L_fucos PF01120.12 CEP08256.1 - 5.9e-88 295.0 0.6 9.4e-88 294.4 0.5 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 CEP08256.1 - 0.075 13.0 0.4 1.7 8.6 0.0 3.2 4 0 0 4 4 4 0 Hypothetical glycosyl hydrolase 6 TFIIB PF00382.14 CEP08257.1 - 7.6e-37 124.9 1.1 3.1e-19 68.5 0.0 3.2 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CEP08257.1 - 8.2e-20 70.8 2.1 8.2e-20 70.8 1.4 2.9 2 0 0 2 2 2 1 Brf1-like TBP-binding domain HSP70 PF00012.15 CEP08258.1 - 5.3e-06 24.6 0.2 7.7e-06 24.0 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP08258.1 - 0.0051 15.4 0.5 0.0094 14.5 0.3 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Actin PF00022.14 CEP08259.1 - 3.9e-33 114.4 0.0 7.5e-33 113.5 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CEP08259.1 - 1.1e-05 24.2 0.0 0.00039 19.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CEP08259.1 - 0.091 12.5 1.0 0.56 10.0 0.1 2.4 2 0 0 2 2 2 0 Cell division protein FtsA Tmemb_cc2 PF10267.4 CEP08259.1 - 0.24 9.9 2.2 0.42 9.1 1.6 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CENP-F_leu_zip PF10473.4 CEP08260.1 - 9.8e-07 28.7 2.0 2e-06 27.7 1.4 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GOLGA2L5 PF15070.1 CEP08260.1 - 0.0053 15.3 6.4 0.0095 14.4 4.4 1.3 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 FlxA PF14282.1 CEP08260.1 - 0.0062 16.4 14.9 0.013 15.4 10.3 1.5 1 0 0 1 1 1 1 FlxA-like protein KxDL PF10241.4 CEP08260.1 - 0.0065 16.3 3.8 0.089 12.7 1.4 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein Tropomyosin_1 PF12718.2 CEP08260.1 - 0.0097 15.7 9.9 0.02 14.7 6.9 1.5 1 0 0 1 1 1 1 Tropomyosin like UpxZ PF06603.6 CEP08260.1 - 0.02 14.9 0.0 0.077 13.0 0.0 2.0 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists MCPsignal PF00015.16 CEP08260.1 - 0.02 14.4 2.3 0.048 13.1 0.2 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FemAB PF02388.11 CEP08260.1 - 0.028 13.1 2.9 0.052 12.2 2.0 1.4 1 0 0 1 1 1 0 FemAB family DUF3153 PF11353.3 CEP08260.1 - 0.08 12.3 1.0 0.13 11.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) V_ATPase_I PF01496.14 CEP08260.1 - 0.091 10.5 3.7 0.11 10.2 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CEP08260.1 - 0.2 11.2 7.4 0.35 10.4 5.1 1.3 1 0 0 1 1 1 0 IncA protein WEMBL PF05701.6 CEP08260.1 - 0.23 9.8 13.4 0.046 12.1 6.3 1.7 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Rotamase_2 PF13145.1 CEP08260.1 - 0.25 11.9 3.0 0.78 10.3 1.3 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain Fzo_mitofusin PF04799.8 CEP08260.1 - 0.66 9.3 6.1 1.4 8.2 4.2 1.5 1 0 0 1 1 1 0 fzo-like conserved region Sec20 PF03908.8 CEP08260.1 - 0.72 9.5 4.0 1.3 8.7 1.7 2.3 1 1 0 1 1 1 0 Sec20 TMPIT PF07851.8 CEP08260.1 - 0.87 8.5 5.6 0.22 10.5 1.7 1.5 2 0 0 2 2 2 0 TMPIT-like protein ATP-synt_B PF00430.13 CEP08260.1 - 1 9.1 11.7 0.78 9.5 4.4 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Lipoprotein_6 PF01441.14 CEP08260.1 - 1 9.1 6.6 0.1 12.3 1.5 1.6 2 0 0 2 2 1 0 Lipoprotein DUF4570 PF15134.1 CEP08260.1 - 1.1 9.1 13.9 16 5.3 8.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) YlqD PF11068.3 CEP08260.1 - 3.5 7.6 11.6 1.1 9.2 5.6 1.9 2 0 0 2 2 2 0 YlqD protein zf-HC5HC2H_2 PF13832.1 CEP08262.1 - 1.9e-16 60.0 8.8 1.9e-16 60.0 6.1 3.7 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CEP08262.1 - 1.1e-12 47.8 1.5 1.1e-12 47.8 1.0 4.2 3 1 0 3 3 3 1 PHD-like zinc-binding domain BAH PF01426.13 CEP08262.1 - 2.4e-10 40.1 0.2 6e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 CEP08262.1 - 9.3e-10 38.0 29.4 1.1e-07 31.3 10.0 5.5 7 1 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 CEP08262.1 - 8.5e-09 34.5 4.4 8.5e-09 34.5 3.0 5.3 5 0 0 5 5 5 2 PHD-finger GATA PF00320.22 CEP08262.1 - 1.4e-05 24.3 0.8 1.4e-05 24.3 0.5 3.4 3 0 0 3 3 3 1 GATA zinc finger ELM2 PF01448.19 CEP08262.1 - 0.00073 20.1 0.0 0.01 16.4 0.0 2.7 2 0 0 2 2 2 1 ELM2 domain Lon_C PF05362.8 CEP08265.1 - 6.6e-71 237.8 0.0 1.3e-70 236.9 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CEP08265.1 - 1.7e-34 119.3 1.1 2.4e-33 115.5 0.8 2.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CEP08265.1 - 4.2e-23 81.9 0.0 1.1e-22 80.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEP08265.1 - 5.3e-07 29.4 0.0 1.4e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 CEP08265.1 - 1e-05 25.0 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 CEP08265.1 - 1.9e-05 24.8 0.0 0.00034 20.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 CEP08265.1 - 5.8e-05 21.9 0.0 0.00011 21.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 CEP08265.1 - 0.00012 21.2 0.0 0.00076 18.6 0.0 2.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CEP08265.1 - 0.00028 21.6 1.9 0.0012 19.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 CEP08265.1 - 0.001 18.9 0.0 0.0032 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CEP08265.1 - 0.0038 16.9 0.2 0.14 11.8 0.0 2.8 1 1 1 2 2 2 1 NTPase AAA_16 PF13191.1 CEP08265.1 - 0.0043 17.0 0.1 0.0043 17.0 0.1 2.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CEP08265.1 - 0.0043 17.3 5.6 0.017 15.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain SKI PF01202.17 CEP08265.1 - 0.0075 16.1 0.1 0.067 13.0 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Phage_connect_1 PF05135.8 CEP08265.1 - 0.029 14.5 1.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein AAA_19 PF13245.1 CEP08265.1 - 0.031 14.0 0.1 0.12 12.1 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 CEP08265.1 - 0.032 13.8 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CEP08265.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CEP08265.1 - 0.065 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.1 CEP08265.1 - 0.43 10.4 5.3 29 4.4 0.0 3.7 3 1 1 4 4 4 0 AAA domain RHIM PF12721.2 CEP08266.1 - 2.6 8.5 5.4 20 5.6 0.1 2.4 2 1 0 2 2 2 0 RIP homotypic interaction motif DUF605 PF04652.11 CEP08266.1 - 3 7.1 7.6 3.3 6.9 5.3 1.0 1 0 0 1 1 1 0 Vta1 like Exo_endo_phos PF03372.18 CEP08267.1 - 1.5e-21 77.4 0.7 2.6e-21 76.6 0.3 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP08267.1 - 3.2e-13 49.3 0.2 6.3e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 CEP08267.1 - 1e-12 47.7 2.9 2.9e-12 46.3 2.0 1.8 1 0 0 1 1 1 1 GRF zinc finger UPF0193 PF05250.6 CEP08267.1 - 0.12 11.9 2.4 0.19 11.3 1.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) CytochromB561_N PF09786.4 CEP08267.1 - 0.4 9.0 12.5 0.58 8.5 8.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SprA-related PF12118.3 CEP08267.1 - 0.54 9.5 12.5 0.74 9.0 8.7 1.1 1 0 0 1 1 1 0 SprA-related family Pkinase PF00069.20 CEP08268.1 - 2e-61 207.4 0.0 3.2e-61 206.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08268.1 - 1.8e-38 132.0 0.0 3.8e-38 131.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP08268.1 - 2.3e-06 26.8 0.0 3.9e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CEP08268.1 - 0.00014 21.2 0.1 0.00067 19.0 0.0 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 CEP08268.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP08268.1 - 0.0037 16.8 0.4 0.006 16.1 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CEP08268.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Whi5 PF08528.6 CEP08270.1 - 0.00073 19.0 0.3 0.0014 18.1 0.2 1.5 1 0 0 1 1 1 1 Whi5 like Band_3_cyto PF07565.8 CEP08270.1 - 0.052 13.0 0.3 0.06 12.8 0.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2250 PF10007.4 CEP08270.1 - 0.065 13.1 5.9 0.15 12.0 3.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF2305 PF10230.4 CEP08271.1 - 1.3e-67 228.0 0.2 1.6e-67 227.7 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CEP08271.1 - 1.8e-12 47.6 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP08271.1 - 1.7e-07 31.1 0.0 3.8e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEP08271.1 - 3.1e-05 23.6 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 CEP08271.1 - 0.00034 20.2 0.0 0.00072 19.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CEP08271.1 - 0.039 13.5 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_8 PF06259.7 CEP08271.1 - 0.04 13.4 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF3089 PF11288.3 CEP08271.1 - 0.046 12.8 0.0 0.1 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Peptidase_S9 PF00326.16 CEP08271.1 - 0.073 12.2 0.1 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.17 CEP08271.1 - 0.073 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF2920 PF11144.3 CEP08271.1 - 0.075 12.0 1.0 7.9 5.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2920) DUF1749 PF08538.5 CEP08271.1 - 0.089 11.6 0.0 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF1057 PF06342.7 CEP08271.1 - 0.089 11.5 0.7 0.24 10.1 0.5 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) cobW PF02492.14 CEP08272.1 - 3.6e-38 130.7 0.8 5.2e-38 130.2 0.6 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CEP08272.1 - 5.9e-11 41.9 0.0 1.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_14 PF13173.1 CEP08272.1 - 0.00027 20.8 0.4 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 CEP08272.1 - 0.00056 19.1 0.5 0.2 10.8 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.13 CEP08272.1 - 0.0029 17.1 0.0 0.008 15.7 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 CEP08272.1 - 0.0038 16.9 0.5 0.024 14.3 0.0 2.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 CEP08272.1 - 0.0042 17.2 0.5 0.021 14.9 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP08272.1 - 0.0085 16.4 0.3 0.023 15.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.15 CEP08272.1 - 0.013 14.2 6.6 0.069 11.8 2.6 2.4 1 1 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 CEP08272.1 - 0.019 14.8 1.2 0.11 12.5 0.5 2.6 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CEP08272.1 - 0.022 14.1 0.1 0.068 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain T2SE PF00437.15 CEP08272.1 - 0.029 13.2 0.0 0.061 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 CEP08272.1 - 0.038 13.6 0.1 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 CEP08272.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CEP08272.1 - 0.066 12.7 1.5 0.58 9.6 1.1 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 CEP08272.1 - 0.074 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 CEP08272.1 - 0.079 13.2 1.6 0.33 11.2 1.1 2.2 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CEP08272.1 - 0.088 12.3 0.1 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP08272.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Velvet PF11754.3 CEP08272.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Velvet factor MobB PF03205.9 CEP08272.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CEP08272.1 - 0.11 13.2 0.1 0.2 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CEP08272.1 - 0.76 10.0 8.6 1.6 8.9 6.0 1.7 1 1 0 1 1 1 0 AAA domain NAD_binding_6 PF08030.7 CEP08273.1 - 1.1e-13 51.3 1.5 3.9e-12 46.3 1.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CEP08273.1 - 1.3e-10 41.3 11.9 1.3e-10 41.3 8.2 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CEP08273.1 - 0.001 18.9 0.0 0.0043 16.8 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 CEP08273.1 - 0.0049 17.4 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PV-1 PF06637.6 CEP08273.1 - 0.23 9.9 1.1 0.36 9.3 0.8 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF3784 PF12650.2 CEP08273.1 - 0.27 11.1 0.0 0.27 11.1 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3784) SDH_alpha PF03313.10 CEP08275.1 - 1.2e-102 342.7 0.2 1.8e-102 342.2 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 CEP08275.1 - 6.3e-56 188.8 0.1 1.2e-55 187.8 0.1 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain Glyco_hydro_10 PF00331.15 CEP08275.1 - 0.0013 17.8 0.5 0.0067 15.4 0.1 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 10 MmgE_PrpD PF03972.9 CEP08275.1 - 0.031 12.4 1.2 0.048 11.8 0.9 1.2 1 0 0 1 1 1 0 MmgE/PrpD family JCAD PF15351.1 CEP08275.1 - 0.32 8.5 0.3 0.47 8.0 0.2 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Phosphodiest PF01663.17 CEP08276.1 - 5.9e-77 259.4 2.6 7.6e-77 259.0 1.8 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CEP08276.1 - 1.7e-07 30.7 1.1 2e-05 23.9 0.7 2.8 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CEP08276.1 - 2.1e-05 24.0 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.7 CEP08276.1 - 0.005 16.5 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 PglZ domain Phosphoesterase PF04185.9 CEP08276.1 - 0.011 14.9 0.2 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoesterase family potato_inhibit PF00280.13 CEP08276.1 - 0.013 15.6 0.1 0.032 14.3 0.1 1.7 1 0 0 1 1 1 0 Potato inhibitor I family PC-Esterase PF13839.1 CEP08277.1 - 6.8e-23 81.8 0.2 9.1e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.1 CEP08277.1 - 0.059 13.4 4.6 0.2 11.7 3.2 1.9 1 1 0 1 1 1 0 PMR5 N terminal Domain HrpB4 PF09502.5 CEP08278.1 - 0.051 12.7 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) Solute_trans_a PF03619.11 CEP08279.1 - 1.1e-91 306.9 16.9 1.4e-91 306.5 11.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3829 PF12889.2 CEP08279.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) SCIMP PF15050.1 CEP08279.1 - 0.22 11.3 1.5 0.46 10.3 1.0 1.6 1 0 0 1 1 1 0 SCIMP protein Glyoxal_oxid_N PF07250.6 CEP08280.1 - 1e-61 208.1 0.0 1.5e-59 201.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CEP08280.1 - 1.6e-19 69.7 0.0 2.8e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 CEP08280.1 - 8.4e-05 22.2 0.1 2.3 8.0 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Fasciclin PF02469.17 CEP08281.1 - 1.2e-27 96.4 0.3 1.4e-12 47.7 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain SKG6 PF08693.5 CEP08282.1 - 0.012 14.9 0.1 0.1 11.9 0.0 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Rax2 PF12768.2 CEP08282.1 - 0.018 14.2 0.0 0.045 12.9 0.0 1.7 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TIMELESS_C PF05029.8 CEP08282.1 - 0.21 10.4 9.1 0.27 10.1 6.3 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region DUF2217 PF10265.4 CEP08282.1 - 0.92 8.1 6.4 1.7 7.3 4.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) VTC PF09359.5 CEP08283.1 - 1.5e-39 135.7 6.3 1.5e-39 135.7 4.3 2.0 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.10 CEP08283.1 - 1.1e-09 38.3 4.4 1.1e-09 38.3 3.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.14 CEP08283.1 - 9e-08 32.2 30.4 1.4e-06 28.3 10.8 4.5 3 1 0 3 3 3 1 SPX domain Glycos_transf_4 PF00953.16 CEP08283.1 - 0.023 14.5 0.1 0.038 13.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 VTC PF09359.5 CEP08284.1 - 1.7e-84 283.1 0.3 2.8e-84 282.5 0.2 1.3 1 0 0 1 1 1 1 VTC domain Gryzun PF07919.7 CEP08284.1 - 4.4e-66 223.3 0.3 6e-66 222.9 0.2 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 CEP08284.1 - 4.3e-51 173.7 0.1 9.6e-50 169.3 0.1 2.5 1 1 0 1 1 1 1 Foie gras liver health family 1 SPX PF03105.14 CEP08284.1 - 6.5e-17 62.2 2.9 9.9e-08 32.0 0.0 3.4 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 CEP08284.1 - 2e-08 34.3 2.3 4.1e-08 33.3 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Gryzun-like PF12742.2 CEP08284.1 - 1.2e-05 25.0 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Apc3 PF12895.2 CEP08284.1 - 0.027 14.6 0.0 0.16 12.1 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CEP08284.1 - 0.068 13.1 0.5 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP08284.1 - 0.094 12.5 0.0 3 7.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat dsDNA_bind PF01984.15 CEP08286.1 - 8.4e-31 106.1 2.9 1e-30 105.8 2.0 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TPR_20 PF14561.1 CEP08286.1 - 0.052 13.6 2.2 0.083 13.0 1.5 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-1_beta_acid PF10587.4 CEP08286.1 - 0.12 12.5 0.7 0.12 12.5 0.5 3.0 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region DUF3333 PF11812.3 CEP08286.1 - 0.26 11.2 2.9 0.33 10.9 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) DUF2802 PF10975.3 CEP08287.1 - 1.3 8.7 5.4 8.5 6.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) Zn_ribbon_recom PF13408.1 CEP08288.1 - 0.037 14.2 0.4 0.065 13.4 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain SDA1 PF05285.7 CEP08288.1 - 1.3 8.2 6.6 1.7 7.8 4.6 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.5 CEP08288.1 - 6.6 7.0 10.5 15 5.9 7.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UpxZ PF06603.6 CEP08289.1 - 0.0072 16.3 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 UpxZ family of transcription anti-terminator antagonists DUF359 PF04019.7 CEP08289.1 - 0.067 12.5 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF359) MFS_1 PF07690.11 CEP08290.1 - 8.3e-15 54.3 64.1 4.1e-08 32.3 18.0 2.5 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 CEP08290.1 - 3.2e-08 33.2 3.0 3.2e-08 33.2 2.1 3.3 3 0 0 3 3 3 1 MFS_1 like family Nuc_H_symport PF03825.11 CEP08290.1 - 8.1e-06 24.8 12.8 8.1e-06 24.8 8.9 2.4 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_2 PF13347.1 CEP08290.1 - 1.3e-05 23.7 7.5 1.3e-05 23.7 5.2 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein Pam17 PF08566.5 CEP08290.1 - 1.5 8.4 3.9 2.5 7.7 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 LacY_symp PF01306.14 CEP08290.1 - 5.6 5.3 25.8 0.059 11.9 5.1 2.3 2 1 0 2 2 2 0 LacY proton/sugar symporter Integrase_AP2 PF14657.1 CEP08293.1 - 4.9 7.0 5.9 2.4 8.0 1.6 2.2 2 0 0 2 2 2 0 AP2-like DNA-binding integrase domain RhoGAP PF00620.22 CEP08294.1 - 5.3e-36 123.5 0.0 9e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Colipase PF01114.13 CEP08294.1 - 0.054 12.9 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Colipase, N-terminal domain EF-hand_7 PF13499.1 CEP08295.1 - 2.3e-11 43.6 1.4 2.3e-11 43.6 1.0 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CEP08295.1 - 1.1e-08 33.7 0.5 0.0005 19.1 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CEP08295.1 - 1.3e-07 30.8 2.2 0.00014 21.4 0.4 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CEP08295.1 - 4.9e-06 26.0 2.7 0.048 13.2 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CEP08295.1 - 9.3e-06 24.7 3.3 0.065 12.6 0.0 2.7 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 CEP08295.1 - 0.0047 16.9 0.1 0.029 14.4 0.1 2.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region FG-GAP PF01839.18 CEP08295.1 - 0.43 10.3 0.3 0.43 10.3 0.2 2.6 3 0 0 3 3 3 0 FG-GAP repeat ELO PF01151.13 CEP08296.1 - 1e-55 188.7 29.2 1.2e-55 188.4 20.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CAAP1 PF15335.1 CEP08296.1 - 0.011 15.8 0.2 0.052 13.7 0.0 2.0 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 DUF1049 PF06305.6 CEP08296.1 - 0.17 11.3 2.5 0.21 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PC-Esterase PF13839.1 CEP08297.1 - 1.4e-06 28.3 0.0 1.5e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Acyltransferase PF01553.16 CEP08298.1 - 2.5e-36 124.0 0.1 3.6e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase YlaH PF14036.1 CEP08298.1 - 0.0027 17.7 0.5 0.0055 16.7 0.3 1.5 1 0 0 1 1 1 1 YlaH-like protein YrhC PF14143.1 CEP08298.1 - 0.13 12.2 0.7 2.8 7.9 0.1 2.4 2 0 0 2 2 2 0 YrhC-like protein P34-Arc PF04045.9 CEP08299.1 - 6.5e-101 336.6 2.3 9.4e-101 336.1 1.6 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc NDK PF00334.14 CEP08299.1 - 2.3e-23 82.4 0.0 5.2e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF667 PF05018.8 CEP08300.1 - 1.6e-80 268.8 0.0 2.5e-80 268.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.20 CEP08301.1 - 1.9e-40 138.6 0.1 7.1e-21 74.5 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08301.1 - 1.5e-13 50.4 0.1 5.5e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 CEP08301.1 - 0.03 13.6 0.0 0.073 12.4 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Wbp11 PF09429.5 CEP08301.1 - 0.24 11.3 11.8 0.089 12.7 5.2 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 DUF3818 PF12825.2 CEP08302.1 - 4.3e-75 252.5 5.6 1.6e-74 250.5 3.9 1.9 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CEP08302.1 - 1.5e-15 57.0 3.3 1.7e-15 56.8 1.2 2.0 2 0 0 2 2 2 1 PX-associated PX PF00787.19 CEP08302.1 - 7.1e-13 48.3 0.4 1.8e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 PX domain Myb_DNA-bind_6 PF13921.1 CEP08303.1 - 6.1e-06 26.2 0.0 1.7e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_23 PF13384.1 CEP08303.1 - 6.5e-06 25.6 0.2 1.5e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP08303.1 - 0.01 15.9 0.1 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.1 CEP08303.1 - 0.085 12.8 0.6 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Myb_DNA-binding PF00249.26 CEP08303.1 - 0.26 11.3 5.8 0.27 11.3 1.3 2.9 2 1 1 3 3 3 0 Myb-like DNA-binding domain CDC50 PF03381.10 CEP08304.1 - 8.7e-92 307.2 0.0 1e-91 306.9 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RGS PF00615.14 CEP08305.1 - 2.2e-16 60.0 6.5 3.3e-16 59.4 3.8 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.6 CEP08305.1 - 1.1e-05 25.0 0.7 2e-05 24.2 0.5 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain RICTOR_N PF14664.1 CEP08307.1 - 0.013 14.1 0.0 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Drf_GBD PF06371.8 CEP08307.1 - 0.051 12.9 0.5 0.083 12.2 0.4 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Bac_DNA_binding PF00216.16 CEP08307.1 - 0.058 13.4 0.2 2.4 8.2 0.1 2.5 1 1 1 2 2 2 0 Bacterial DNA-binding protein RGS PF00615.14 CEP08307.1 - 0.081 13.0 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Regulator of G protein signaling domain JmjC PF02373.17 CEP08308.1 - 3.5e-16 59.4 1.2 7.2e-16 58.4 0.5 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CEP08308.1 - 1.5e-15 57.3 1.6 2e-15 57.0 1.1 1.2 1 0 0 1 1 1 1 Cupin-like domain GPI PF06560.6 CEP08308.1 - 0.04 12.9 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) SpoU_methylase PF00588.14 CEP08309.1 - 2.2e-23 82.7 0.0 4.3e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SRF-TF PF00319.13 CEP08310.1 - 5.7e-20 70.2 0.1 9.8e-20 69.5 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CNF1 PF05785.7 CEP08310.1 - 0.083 11.7 1.2 0.17 10.7 0.1 1.8 2 0 0 2 2 2 0 Rho-activating domain of cytotoxic necrotizing factor PAT1 PF09770.4 CEP08310.1 - 1.6 6.8 38.2 2 6.5 26.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNF5 PF04855.7 CEP08311.1 - 2e-49 168.2 12.9 9.1e-28 97.3 0.4 3.2 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 HA2 PF04408.18 CEP08311.1 - 2.3e-27 95.0 0.0 2.3e-27 95.0 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEP08311.1 - 5.8e-21 74.4 0.0 3.3e-20 72.0 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEP08311.1 - 3e-14 52.6 0.0 6.7e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP08311.1 - 2.9e-10 39.8 0.4 6.3e-10 38.8 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEP08311.1 - 0.00011 22.3 0.1 0.0011 19.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CEP08311.1 - 0.00032 20.3 0.2 0.00094 18.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 CEP08311.1 - 0.0047 16.0 0.1 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 CEP08311.1 - 0.0077 15.1 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.1 CEP08311.1 - 0.011 15.3 0.0 0.011 15.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain Flavi_DEAD PF07652.9 CEP08311.1 - 0.019 14.6 0.1 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain Kinesin PF00225.18 CEP08311.1 - 0.035 12.8 0.9 0.07 11.8 0.6 1.4 1 0 0 1 1 1 0 Kinesin motor domain ABC_tran PF00005.22 CEP08311.1 - 0.07 13.4 2.6 0.41 10.9 0.2 2.9 2 1 0 2 2 1 0 ABC transporter Ribosomal_L32e PF01655.13 CEP08312.1 - 2.1e-47 159.7 1.0 2.5e-47 159.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Pro_isomerase PF00160.16 CEP08313.1 - 6.9e-41 140.0 0.9 9.2e-41 139.6 0.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LLC1 PF14945.1 CEP08313.1 - 0.026 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein CryBP1 PF07029.6 CEP08313.1 - 0.086 12.5 0.2 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 CryBP1 protein Histone PF00125.19 CEP08314.1 - 8.2e-22 77.1 0.0 1.1e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEP08314.1 - 0.0003 20.7 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myosin_head PF00063.16 CEP08315.1 - 5.2e-233 775.0 0.6 8.3e-233 774.3 0.4 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CEP08315.1 - 4.8e-42 143.5 0.2 8.4e-42 142.7 0.1 1.3 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 CEP08315.1 - 1.3e-14 53.3 0.3 2.7e-14 52.2 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP08315.1 - 3.4e-12 45.6 0.0 8.8e-12 44.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CEP08315.1 - 7.8e-12 44.5 0.1 2.1e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CEP08315.1 - 0.00028 21.0 0.2 0.00028 21.0 0.2 1.9 2 0 0 2 2 1 1 Bacterial SH3 domain AAA_22 PF13401.1 CEP08315.1 - 0.0046 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEP08315.1 - 0.016 14.3 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 CEP08315.1 - 0.018 15.8 0.0 0.057 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 CEP08315.1 - 0.037 13.3 0.4 4.1 6.6 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.1 CEP08315.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SH3_4 PF06347.8 CEP08315.1 - 0.064 12.8 0.2 0.22 11.1 0.1 1.9 1 0 0 1 1 1 0 Bacterial SH3 domain IQ PF00612.22 CEP08315.1 - 0.067 12.8 8.6 0.38 10.5 0.3 3.3 3 0 0 3 3 2 0 IQ calmodulin-binding motif AAA_18 PF13238.1 CEP08315.1 - 0.067 13.5 0.0 0.29 11.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP08315.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zds_C PF08632.5 CEP08316.1 - 2.3e-19 68.5 1.4 4.2e-19 67.6 1.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term ACOX PF01756.14 CEP08317.1 - 2.9e-31 108.2 0.1 1.2e-30 106.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEP08317.1 - 2.2e-15 57.0 0.1 5.6e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEP08317.1 - 4e-12 45.4 0.6 8.4e-12 44.4 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEP08317.1 - 0.028 14.5 0.5 0.26 11.3 0.0 2.6 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain OPT PF03169.10 CEP08318.1 - 1.7e-153 512.3 48.4 6.4e-152 507.1 33.6 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 CEP08318.1 - 0.55 9.3 2.1 2.9 6.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) ABC_tran PF00005.22 CEP08319.1 - 1.9e-36 125.3 0.0 5.3e-36 123.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CEP08319.1 - 8.1e-29 100.8 6.0 1.1e-28 100.4 4.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CEP08319.1 - 2.1e-06 27.9 0.5 0.00048 20.1 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP08319.1 - 1e-05 25.6 0.0 4.7e-05 23.4 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain SMC_N PF02463.14 CEP08319.1 - 3.5e-05 23.1 0.1 0.0005 19.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CEP08319.1 - 9.4e-05 22.5 0.1 0.0012 19.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CEP08319.1 - 0.00057 20.0 0.1 0.017 15.3 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEP08319.1 - 0.0013 18.4 0.0 0.049 13.3 0.0 2.8 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CEP08319.1 - 0.003 17.4 0.0 0.034 14.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP08319.1 - 0.0056 17.5 0.0 0.021 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 CEP08319.1 - 0.014 15.3 0.3 0.086 12.7 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 CEP08319.1 - 0.019 14.1 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CEP08319.1 - 0.02 14.8 0.1 2.4 8.0 0.0 2.7 1 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CEP08319.1 - 0.027 13.8 0.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CEP08319.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 CEP08319.1 - 0.046 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 CEP08319.1 - 0.059 13.6 0.1 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CEP08319.1 - 0.068 12.6 0.1 0.63 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain PTPlike_phytase PF14566.1 CEP08320.1 - 1.5e-111 369.0 1.4 8.6e-42 142.6 0.1 4.5 3 1 1 4 4 4 3 Inositol hexakisphosphate DSPc PF00782.15 CEP08320.1 - 0.001 18.6 0.0 0.014 14.9 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP08320.1 - 0.005 16.2 0.0 0.079 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase MAAL_C PF07476.6 CEP08320.1 - 0.048 12.5 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Cyclin PF08613.6 CEP08321.1 - 0.00071 20.0 0.1 0.00071 20.0 0.1 2.9 1 1 1 3 3 3 1 Cyclin Cyclin_N PF00134.18 CEP08321.1 - 0.0099 15.4 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF605 PF04652.11 CEP08321.1 - 0.19 11.0 9.9 0.31 10.4 6.8 1.2 1 0 0 1 1 1 0 Vta1 like UPF0560 PF10577.4 CEP08323.1 - 0.044 12.0 2.6 0.039 12.2 1.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ERF PF04404.7 CEP08323.1 - 9.9 5.6 10.8 4.8 6.7 5.9 1.5 2 0 0 2 2 2 0 ERF superfamily Methyltransf_16 PF10294.4 CEP08324.1 - 6.8e-32 110.2 0.4 4.1e-30 104.4 0.3 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEP08324.1 - 2.4e-06 28.0 0.0 5e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP08324.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP08324.1 - 0.00056 19.9 0.0 0.0098 15.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP08324.1 - 0.00073 19.2 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP08324.1 - 0.0018 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CEP08324.1 - 0.029 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MethyltransfD12 PF02086.10 CEP08324.1 - 0.033 13.6 0.0 0.069 12.6 0.0 1.6 1 1 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_12 PF08242.7 CEP08324.1 - 0.033 14.6 0.1 0.073 13.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 CEP08324.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Fungal_trans PF04082.13 CEP08325.1 - 2.4e-34 118.3 0.9 3.8e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP08325.1 - 3.7e-09 36.3 12.1 7.6e-09 35.3 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YhhN PF07947.9 CEP08325.1 - 0.051 12.9 1.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 YhhN-like protein TFIIF_alpha PF05793.7 CEP08326.1 - 6.2 5.0 14.4 12 4.1 10.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GARS_A PF01071.14 CEP08327.1 - 5.2e-83 277.3 0.0 9.4e-83 276.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CEP08327.1 - 8.9e-36 122.3 0.4 4.2e-35 120.1 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CEP08327.1 - 1.1e-32 113.1 0.0 2.7e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CEP08327.1 - 1.9e-30 104.8 0.4 4.3e-30 103.7 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CEP08327.1 - 2.6e-16 59.6 2.3 1e-15 57.7 0.6 2.6 3 0 0 3 3 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 CEP08327.1 - 5.4e-09 36.0 0.0 1.7e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP08327.1 - 3.1e-08 32.7 0.0 6.1e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CEP08327.1 - 4.7e-05 22.8 0.0 9.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CEP08327.1 - 0.00014 21.2 0.3 0.00033 20.0 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 CEP08327.1 - 0.0012 18.3 0.0 0.003 17.0 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CEP08327.1 - 0.0068 16.2 0.0 0.028 14.2 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 CEP08327.1 - 0.039 13.3 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain Phage_int_SAM_1 PF02899.12 CEP08328.1 - 0.0086 16.2 0.0 0.071 13.2 0.0 2.3 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain ING PF12998.2 CEP08329.1 - 7.5e-20 71.1 0.5 2.3e-19 69.5 0.3 1.9 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Fungal_trans PF04082.13 CEP08329.1 - 3.4e-08 32.6 2.1 6.8e-08 31.6 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.24 CEP08329.1 - 1.6e-07 30.8 7.3 4.2e-07 29.5 5.1 1.7 1 0 0 1 1 1 1 PHD-finger DUF3325 PF11804.3 CEP08329.1 - 0.0097 15.8 0.5 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) BCIP PF13862.1 CEP08330.1 - 2.1e-61 206.8 4.7 3.1e-61 206.2 3.2 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.27 CEP08331.1 - 2.9e-24 83.9 10.5 0.00011 21.9 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat LisH PF08513.6 CEP08331.1 - 0.00015 21.3 0.4 0.00059 19.5 0.1 2.1 2 0 0 2 2 2 1 LisH RNA_pol_I_A49 PF06870.7 CEP08332.1 - 4e-78 262.6 4.5 4.6e-78 262.4 3.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Methyltransf_31 PF13847.1 CEP08333.1 - 2.3e-12 46.7 0.1 3.7e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CEP08333.1 - 1.1e-10 41.1 0.1 1.7e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CEP08333.1 - 2.1e-10 41.1 0.1 9e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP08333.1 - 4.2e-09 36.7 0.0 9.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP08333.1 - 4.5e-09 36.3 0.0 7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CEP08333.1 - 4.5e-08 32.4 0.1 5.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 CEP08333.1 - 1.1e-07 31.7 0.0 2.8e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CEP08333.1 - 5.8e-06 25.7 0.2 1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CEP08333.1 - 9.3e-06 26.0 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CEP08333.1 - 1e-05 24.4 0.1 1.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 CEP08333.1 - 1.8e-05 23.9 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CEP08333.1 - 2.4e-05 24.5 0.1 0.00011 22.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 CEP08333.1 - 0.00047 20.1 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 CEP08333.1 - 0.017 15.9 0.0 0.038 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CEP08333.1 - 0.017 14.7 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 CEP08333.1 - 0.025 14.1 0.1 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 CEP08333.1 - 0.039 13.4 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 CEP08333.1 - 0.042 13.0 1.0 0.15 11.1 0.7 2.0 1 1 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.8 CEP08333.1 - 0.1 11.9 0.1 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 SDF PF00375.13 CEP08334.1 - 4.5e-105 351.6 38.7 5.3e-105 351.3 26.8 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family LRR_3 PF07725.7 CEP08335.1 - 0.39 10.5 1.8 2.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat Glyco_trans_2_3 PF13632.1 CEP08336.1 - 1.2e-14 54.4 0.0 1.2e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Ycf1 PF05758.7 CEP08337.1 - 0.0024 15.7 0.5 0.0025 15.6 0.4 1.0 1 0 0 1 1 1 1 Ycf1 Zn_clus PF00172.13 CEP08337.1 - 0.056 13.3 2.0 0.11 12.4 1.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 CEP08337.1 - 0.076 11.2 24.2 0.097 10.8 16.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CEP08337.1 - 0.17 10.2 6.1 0.24 9.7 4.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 CEP08337.1 - 0.18 11.6 1.9 0.24 11.2 1.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAS PF00989.19 CEP08337.1 - 0.29 10.9 3.5 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 PAS fold Med15 PF09606.5 CEP08337.1 - 0.41 8.7 38.8 0.55 8.3 26.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LIM_bind PF01803.11 CEP08337.1 - 0.57 9.2 13.5 32 3.5 0.0 2.2 2 0 0 2 2 2 0 LIM-domain binding protein Pex14_N PF04695.8 CEP08337.1 - 0.92 9.5 19.9 0.82 9.7 11.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK5_activator PF03261.10 CEP08337.1 - 1.2 8.4 12.2 2.4 7.4 8.4 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein MRP-S26 PF14943.1 CEP08337.1 - 1.8 8.0 15.8 3.1 7.3 10.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Hid1 PF12722.2 CEP08337.1 - 2.6 5.5 12.3 4.2 4.9 8.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 CEP08337.1 - 3.1 6.5 11.2 4.7 5.9 7.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3381 PF11861.3 CEP08337.1 - 4.7 6.7 12.7 1.3e+02 2.0 9.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Band_3_cyto PF07565.8 CEP08337.1 - 5.5 6.4 11.2 9.4 5.6 7.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FimP PF09766.4 CEP08337.1 - 6.1 5.7 25.6 11 5.0 17.8 1.3 1 0 0 1 1 1 0 Fms-interacting protein DHHW PF14286.1 CEP08337.1 - 6.2 6.0 10.0 16 4.7 6.9 1.6 1 0 0 1 1 1 0 DHHW protein NARP1 PF12569.3 CEP08337.1 - 8.5 4.9 13.3 16 4.1 9.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4407 PF14362.1 CEP08337.1 - 10 5.0 16.3 15 4.4 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MutS_V PF00488.16 CEP08338.1 - 3.9e-90 301.3 0.0 6.2e-90 300.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CEP08338.1 - 2.2e-39 135.3 6.7 4.1e-39 134.4 4.6 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CEP08338.1 - 1.2e-23 83.2 0.0 3.5e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CEP08338.1 - 5.5e-15 55.6 0.0 2.3e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 CEP08338.1 - 7.4e-05 22.8 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 CEP08338.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CEP08338.1 - 0.2 11.9 0.3 17 5.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain SGL PF08450.7 CEP08339.1 - 0.0058 16.0 0.0 0.98 8.7 0.0 2.7 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region CENP-F_leu_zip PF10473.4 CEP08340.1 - 5.1e-06 26.3 7.4 5.1e-06 26.3 5.1 3.3 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0180 PF03698.8 CEP08340.1 - 0.039 13.7 0.2 0.098 12.5 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) GAS PF13851.1 CEP08340.1 - 1.2 8.3 30.2 0.17 11.0 3.5 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding eIF3_subunit PF08597.5 CEP08341.1 - 3.2e-32 112.0 44.8 5.5e-32 111.2 31.0 1.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3861 PF12977.2 CEP08341.1 - 0.026 14.6 2.7 0.3 11.2 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF4164 PF13747.1 CEP08341.1 - 3.6 7.7 11.1 0.86 9.7 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) GST_N_3 PF13417.1 CEP08342.1 - 2.4e-21 75.7 0.0 4.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP08342.1 - 2.1e-17 62.8 0.0 3.3e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP08342.1 - 1.5e-11 44.2 0.0 3.5e-10 39.9 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEP08342.1 - 3.2e-06 26.9 0.0 5.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP08342.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP08342.1 - 0.0028 18.0 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CEP08342.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 CEP08342.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Trehalase PF01204.13 CEP08343.1 - 5.2e-174 579.6 0.9 6.5e-174 579.3 0.6 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CEP08343.1 - 4.8e-14 51.3 1.8 4.8e-14 51.3 1.3 2.3 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain DisA-linker PF10635.4 CEP08343.1 - 0.14 11.6 0.6 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region F-box-like PF12937.2 CEP08344.1 - 1.3e-06 27.9 0.4 9e-06 25.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 CEP08345.1 - 5.4e-06 26.0 0.5 5.4e-06 26.0 0.4 2.6 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 CEP08346.1 - 5.8e-08 32.3 0.9 1.5e-07 31.0 0.6 1.8 1 0 0 1 1 1 1 F-box-like Ran_BP1 PF00638.13 CEP08347.1 - 7.8e-16 58.2 0.4 7.8e-16 58.2 0.3 2.4 2 1 0 2 2 2 1 RanBP1 domain DUF2428 PF10350.4 CEP08348.1 - 3.5e-72 242.5 0.1 9.5e-72 241.0 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 CEP08348.1 - 0.00041 20.1 4.5 24 5.3 0.1 6.7 6 0 0 6 6 6 1 HEAT repeat Nucleoplasmin PF03066.10 CEP08348.1 - 0.26 10.8 2.3 0.55 9.7 1.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CEP08348.1 - 1.6 9.1 5.4 3.8 7.8 3.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribonuc_red_lgC PF02867.10 CEP08349.1 - 4.3e-219 728.5 0.0 5.8e-219 728.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CEP08349.1 - 5.6e-24 83.7 0.1 1.6e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CEP08349.1 - 1.9e-17 63.4 0.3 1.9e-16 60.2 0.0 2.7 3 0 0 3 3 3 1 ATP cone domain Glyco_transf_15 PF01793.11 CEP08350.1 - 6.1e-125 416.5 15.8 8.2e-125 416.1 10.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SH3_9 PF14604.1 CEP08350.1 - 5.3e-44 147.5 0.7 3.1e-16 58.6 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 CEP08350.1 - 2.1e-35 119.8 2.6 2.9e-11 42.5 0.1 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CEP08350.1 - 5.3e-34 115.4 0.0 3.5e-10 39.2 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain XFP PF03894.10 CEP08350.1 - 0.02 14.4 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPR_11 PF13414.1 CEP08351.1 - 0.00082 18.9 0.1 0.014 15.0 0.1 2.3 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CEP08351.1 - 0.0016 17.9 0.1 0.49 10.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CEP08351.1 - 0.0018 18.0 0.1 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP08351.1 - 0.027 14.4 0.1 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEP08351.1 - 0.079 13.6 0.3 7.6 7.4 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CEP08351.1 - 0.29 11.4 1.2 10 6.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 CEP08352.1 - 2.6e-16 59.0 0.1 4.7e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP08352.1 - 1.7e-12 47.0 0.0 4.1e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP08352.1 - 2.6e-08 33.6 0.1 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3227 PF11537.3 CEP08352.1 - 0.021 14.9 0.7 0.043 13.9 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3227) Nup35_RRM_2 PF14605.1 CEP08352.1 - 0.045 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Asp PF00026.18 CEP08353.1 - 3.7e-81 272.8 2.8 4.6e-81 272.5 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribosomal_L34e PF01199.13 CEP08353.1 - 9.5e-40 134.7 5.8 1.6e-39 133.9 4.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L34e TAXi_C PF14541.1 CEP08353.1 - 7.9e-06 25.5 0.0 7.8e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 CEP08353.1 - 1.8e-05 24.7 0.0 0.002 18.0 0.0 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEP08353.1 - 0.021 15.3 0.1 5 7.7 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease MFS_1 PF07690.11 CEP08354.1 - 2.7e-16 59.2 22.7 8e-15 54.3 13.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CEP08354.1 - 1e-06 28.2 3.1 1e-06 28.2 2.2 2.0 3 0 0 3 3 3 1 Nodulin-like F-box-like PF12937.2 CEP08356.1 - 3.3e-06 26.7 0.4 7.8e-06 25.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP08356.1 - 0.0025 17.4 0.1 0.0094 15.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain Cytochrom_B562 PF07361.6 CEP08356.1 - 0.015 15.7 0.9 3.9 7.9 0.3 2.9 2 0 0 2 2 2 0 Cytochrome b562 BCAS2 PF05700.6 CEP08357.1 - 1.3e-54 184.9 14.3 1.6e-54 184.7 9.9 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) THOC7 PF05615.8 CEP08357.1 - 0.016 15.5 5.0 0.016 15.5 3.5 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Fib_alpha PF08702.5 CEP08357.1 - 6.4 6.8 10.5 1.5 8.9 2.9 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.11 CEP08358.1 - 1.1e-14 53.9 31.4 2.5e-14 52.7 21.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CEP08358.1 - 0.0029 17.3 10.2 0.034 13.9 1.0 3.8 3 0 0 3 3 3 1 MFS_1 like family PGG PF13962.1 CEP08358.1 - 1.5 8.4 10.6 0.064 12.8 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function DUF3975 PF13126.1 CEP08358.1 - 9 6.5 10.5 0.5 10.5 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3975) Homeobox PF00046.24 CEP08359.1 - 2e-06 27.2 0.7 5e-06 26.0 0.5 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP08359.1 - 0.029 14.0 0.9 0.068 12.8 0.1 2.1 2 0 0 2 2 2 0 Homeobox KN domain bPH_2 PF03703.9 CEP08359.1 - 0.052 13.5 0.1 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain Mucin PF01456.12 CEP08359.1 - 9 6.0 16.5 1.3 8.8 2.9 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Lipase_GDSL PF00657.17 CEP08360.1 - 2.8e-21 76.4 0.2 4.5e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP08360.1 - 2.8e-07 30.8 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Baculo_PEP_N PF04512.7 CEP08360.1 - 0.074 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus ATG22 PF11700.3 CEP08360.1 - 0.14 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Aa_trans PF01490.13 CEP08361.1 - 1.3e-88 297.2 33.2 1.3e-88 297.2 23.0 2.5 3 1 0 3 3 3 1 Transmembrane amino acid transporter protein MFS_1 PF07690.11 CEP08361.1 - 1.4e-10 40.4 22.6 1.4e-10 40.4 15.7 3.4 2 1 0 3 3 3 1 Major Facilitator Superfamily Nop14 PF04147.7 CEP08361.1 - 0.3 8.9 1.0 0.39 8.5 0.7 1.1 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.3 CEP08361.1 - 2.9 8.5 10.9 6.6 7.4 7.6 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal LSM PF01423.17 CEP08362.1 - 2.5e-20 71.7 0.1 2.8e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain UPF0565 PF10561.4 CEP08362.1 - 0.04 12.8 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PI3K_rbd PF00794.13 CEP08362.1 - 0.043 13.7 0.1 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 PI3-kinase family, ras-binding domain ABC_membrane PF00664.18 CEP08363.1 - 1e-93 313.7 22.6 7.1e-52 176.5 5.9 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 CEP08363.1 - 1.1e-68 229.8 0.1 6.3e-34 117.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Metallophos PF00149.23 CEP08363.1 - 5.7e-17 61.7 0.9 1.1e-16 60.7 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP08363.1 - 1.3e-11 44.6 0.0 2.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SMC_N PF02463.14 CEP08363.1 - 4.8e-11 42.3 7.7 8.6e-06 25.1 0.6 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEP08363.1 - 9.7e-09 35.5 0.0 0.91 9.4 0.0 4.8 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 CEP08363.1 - 1.4e-08 34.9 1.4 0.0028 17.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CEP08363.1 - 3.8e-08 33.5 3.8 0.00095 19.1 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.4 CEP08363.1 - 5.1e-08 31.9 0.5 0.0015 17.2 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class DUF258 PF03193.11 CEP08363.1 - 5.1e-07 29.0 0.5 0.034 13.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEP08363.1 - 3.6e-06 26.4 3.8 0.061 12.8 0.0 3.5 4 0 0 4 4 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CEP08363.1 - 3.6e-06 27.8 0.0 0.087 13.6 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CEP08363.1 - 4e-05 23.5 0.1 0.54 10.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CEP08363.1 - 4.5e-05 23.1 0.6 0.33 10.4 0.0 4.1 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CEP08363.1 - 0.00019 21.7 0.4 2.3 8.5 0.0 4.1 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.1 CEP08363.1 - 0.00035 20.4 3.2 0.84 9.5 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CEP08363.1 - 0.00041 20.5 5.1 1.5 9.0 1.1 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CEP08363.1 - 0.00062 19.4 0.0 1.1 8.9 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 CEP08363.1 - 0.00099 17.9 0.2 0.1 11.2 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 CEP08363.1 - 0.0013 18.1 0.7 1.4 8.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 CEP08363.1 - 0.0014 18.1 1.7 1.5 8.2 0.1 3.7 4 0 0 4 4 3 1 AAA-like domain Zeta_toxin PF06414.7 CEP08363.1 - 0.0017 17.5 0.2 0.61 9.1 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.15 CEP08363.1 - 0.0018 17.0 0.2 1.1 7.8 0.0 2.5 2 1 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.9 CEP08363.1 - 0.0024 17.6 0.9 9.2 5.9 0.0 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CEP08363.1 - 0.0051 16.7 0.1 3 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CEP08363.1 - 0.0089 15.4 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain APS_kinase PF01583.15 CEP08363.1 - 0.012 15.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Mg_chelatase PF01078.16 CEP08363.1 - 0.012 14.7 0.0 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CEP08363.1 - 0.014 15.5 0.0 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 CEP08363.1 - 0.025 14.4 0.0 5.5 6.9 0.0 3.5 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.12 CEP08363.1 - 0.055 13.0 0.5 5.3 6.4 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein GMC_oxred_N PF00732.14 CEP08363.1 - 0.067 12.3 0.1 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase MMR_HSR1 PF01926.18 CEP08363.1 - 0.083 12.8 0.0 11 6.0 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 CEP08363.1 - 0.46 10.7 7.0 18 5.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain CotH PF08757.6 CEP08364.1 - 1.4e-39 136.2 9.1 2.1e-39 135.6 6.3 1.3 1 0 0 1 1 1 1 CotH protein BRF1 PF07741.8 CEP08365.1 - 0.017 15.3 3.2 0.017 15.3 2.2 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain HapK PF11639.3 CEP08365.1 - 0.12 12.9 0.0 0.39 11.3 0.0 1.8 1 0 0 1 1 1 0 REDY-like protein HapK CotH PF08757.6 CEP08366.1 - 1.1e-26 93.8 1.6 1.3e-26 93.6 1.1 1.1 1 0 0 1 1 1 1 CotH protein CPSF100_C PF13299.1 CEP08367.1 - 4.5e-24 85.4 0.0 1.4e-18 67.6 0.0 2.5 1 1 1 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CEP08367.1 - 1.3e-22 80.0 0.0 3.5e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 CEP08367.1 - 5.2e-07 29.4 0.2 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEP08367.1 - 1.7e-05 24.5 0.4 3.8e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CEP08367.1 - 0.00049 19.8 0.0 0.00089 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CEP08367.1 - 0.011 15.4 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 Beta-lactamase superfamily domain EFP PF01132.15 CEP08367.1 - 0.057 13.1 0.3 0.45 10.2 0.2 2.2 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain Ribosomal_L32p PF01783.18 CEP08368.1 - 0.11 12.6 0.3 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Ribosomal L32p protein family TRP PF06011.7 CEP08369.1 - 1e-54 185.8 28.9 1.4e-54 185.3 20.0 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.10 CEP08369.1 - 1.4e-05 25.3 0.1 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ML domain Ppx-GppA PF02541.11 CEP08370.1 - 3.4e-43 147.8 0.0 6e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family SUI1 PF01253.17 CEP08372.1 - 1.3e-25 88.9 1.2 1.8e-25 88.5 0.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 SNF2_N PF00176.18 CEP08373.1 - 2.7e-71 239.8 0.6 1.4e-70 237.4 0.4 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP08373.1 - 1.6e-15 56.6 0.0 1.7e-14 53.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP08373.1 - 2.4e-07 30.3 0.0 8.4e-07 28.6 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.27 CEP08374.1 - 0.00038 20.2 3.6 6.4 6.8 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_S17e PF00833.13 CEP08375.1 - 1e-59 199.6 0.3 1.2e-59 199.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S17 Glyco_hydro_18 PF00704.23 CEP08376.1 - 6.9e-11 42.1 1.3 2.4e-10 40.4 0.1 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 CEP08376.1 - 3.5e-08 33.1 0.5 3.5e-08 33.1 0.3 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) GATA PF00320.22 CEP08377.1 - 6.4e-16 57.4 5.2 1.9e-15 55.9 3.6 1.9 1 0 0 1 1 1 1 GATA zinc finger TauD PF02668.11 CEP08378.1 - 4.9e-45 154.2 0.2 6.5e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RPA_C PF08784.6 CEP08379.1 - 2.1e-09 37.7 0.1 6.2e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 CEP08379.1 - 3.9e-09 36.2 0.1 6.8e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Peptidase_A22B PF04258.8 CEP08380.1 - 3e-79 266.5 11.8 3.9e-79 266.2 8.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Protocadherin PF08374.6 CEP08380.1 - 0.21 11.1 3.3 0.51 9.9 2.3 1.7 1 0 0 1 1 1 0 Protocadherin DUF4190 PF13828.1 CEP08381.1 - 0.12 11.9 0.2 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) DUF4536 PF15055.1 CEP08381.1 - 1 9.5 3.3 1.3 9.1 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4536) Snf7 PF03357.16 CEP08382.1 - 0.073 12.4 3.1 0.15 11.4 2.2 1.5 1 0 0 1 1 1 0 Snf7 HLH PF00010.21 CEP08383.1 - 2.7e-19 68.6 0.6 8.3e-19 67.0 0.4 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CMS1 PF14617.1 CEP08384.1 - 7e-44 149.7 1.3 1.4e-43 148.8 0.9 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit GRAM PF02893.15 CEP08384.1 - 1.4e-17 62.9 0.1 3.3e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 GRAM domain DEAD PF00270.24 CEP08384.1 - 9e-06 25.2 0.1 2.2e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD PF00270.24 CEP08385.1 - 9.2e-47 158.6 0.0 1.7e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP08385.1 - 5.6e-29 99.8 0.0 1.3e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP08385.1 - 2.7e-06 27.3 0.0 8.3e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cyt-b5 PF00173.23 CEP08386.1 - 5.7e-23 80.5 0.3 1.2e-22 79.4 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CEP08386.1 - 4.4e-09 36.7 22.8 4.4e-09 36.7 15.8 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4260 PF14079.1 CEP08386.1 - 0.015 15.1 1.8 0.015 15.1 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) Kua-UEV1_localn PF10520.4 CEP08386.1 - 1.6 8.3 11.7 0.26 10.9 1.4 2.4 1 1 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain Gti1_Pac2 PF09729.4 CEP08387.1 - 2.3e-60 203.2 0.0 2.3e-60 203.2 0.0 2.2 2 1 0 2 2 2 1 Gti1/Pac2 family DDE_3 PF13358.1 CEP08388.1 - 2.4e-19 69.5 0.6 3.8e-19 68.8 0.4 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP08388.1 - 2.4e-16 59.5 0.7 5.5e-16 58.3 0.5 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP08388.1 - 6e-10 39.2 0.6 1.2e-09 38.3 0.2 1.7 2 0 0 2 2 1 1 Winged helix-turn helix TrmB PF01978.14 CEP08388.1 - 7.4e-05 22.3 0.2 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.1 CEP08388.1 - 0.00012 21.5 0.0 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP08388.1 - 0.00016 22.3 1.7 0.00045 20.9 1.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP08388.1 - 0.00047 20.0 0.2 0.013 15.4 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 CEP08388.1 - 0.0006 19.1 0.1 0.076 12.4 0.0 2.9 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.10 CEP08388.1 - 0.0011 18.7 1.2 0.051 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 CEP08388.1 - 0.0013 18.3 0.4 0.18 11.5 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain KorB PF08535.5 CEP08388.1 - 0.0013 18.8 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 KorB domain LacI PF00356.16 CEP08388.1 - 0.0032 17.0 0.2 0.21 11.2 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.5 CEP08388.1 - 0.025 14.1 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_17 PF12728.2 CEP08388.1 - 0.037 14.2 0.0 15 5.9 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.2 CEP08388.1 - 0.067 13.2 1.1 13 5.9 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain Mor PF08765.6 CEP08388.1 - 0.09 12.5 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_1 PF11427.3 CEP08388.1 - 0.11 12.1 0.1 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Tc3 transposase S-methyl_trans PF02574.11 CEP08389.1 - 4.6e-53 180.5 0.1 5.9e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Sulfate_transp PF00916.15 CEP08390.1 - 9.2e-61 205.2 11.6 2e-60 204.1 8.1 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP08390.1 - 4.6e-29 99.9 2.6 4.6e-29 99.9 1.8 2.9 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEP08390.1 - 2.3e-10 39.9 0.0 4.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CEP08390.1 - 0.0076 16.2 0.0 0.032 14.2 0.0 2.0 2 0 0 2 2 2 1 STAS domain Na_H_antiport_2 PF13726.1 CEP08390.1 - 0.82 9.6 5.5 12 5.8 0.4 3.0 2 0 0 2 2 2 0 Na+-H+ antiporter family WAC_Acf1_DNA_bd PF10537.4 CEP08391.1 - 4.6e-32 110.2 0.4 1.3e-31 108.7 0.2 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CEP08391.1 - 1.6e-15 56.6 0.0 2.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 CEP08391.1 - 0.00039 20.2 0.1 0.0011 18.8 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 CEP08391.1 - 0.0022 17.7 0.4 0.0067 16.1 0.3 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Fe-ADH PF00465.14 CEP08392.1 - 5e-106 354.4 0.0 6e-106 354.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CEP08392.1 - 2.5e-16 59.7 0.0 5.4e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 CEP08392.1 - 0.00073 18.9 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein B12-binding PF02310.14 CEP08392.1 - 0.0017 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain Pkinase PF00069.20 CEP08394.1 - 2.9e-66 223.2 0.0 4.5e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08394.1 - 6.3e-27 94.2 0.1 7.4e-26 90.7 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP08394.1 - 2.1e-06 26.9 0.2 0.0026 16.7 0.0 3.1 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 CEP08394.1 - 0.0096 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfate_transp PF00916.15 CEP08395.1 - 7.5e-73 244.9 10.7 7.5e-73 244.9 7.4 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP08395.1 - 4.8e-30 103.0 2.7 4.8e-30 103.0 1.8 2.7 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEP08395.1 - 9.5e-09 34.6 0.0 1.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CEP08395.1 - 0.15 12.0 0.2 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 STAS domain ChAPs PF09295.5 CEP08396.1 - 7e-153 509.0 0.0 1.5e-151 504.6 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 CEP08396.1 - 0.00057 19.9 1.0 1.3 9.2 0.1 3.1 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CEP08396.1 - 0.0021 18.3 0.0 0.085 13.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEP08396.1 - 0.0022 17.5 1.7 1.4 8.6 0.0 3.5 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.1 CEP08396.1 - 0.094 12.5 2.3 26 4.8 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP08396.1 - 0.1 12.5 10.9 0.19 11.7 0.4 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SOBP PF15279.1 CEP08396.1 - 0.66 10.3 6.5 1.1 9.6 4.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Daxx PF03344.10 CEP08396.1 - 3.1 6.1 22.5 4.3 5.7 15.6 1.1 1 0 0 1 1 1 0 Daxx Family Glyco_hydro_17 PF00332.13 CEP08397.1 - 1.4e-11 44.0 0.9 6.2e-07 28.7 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 Complex1_51K PF01512.12 CEP08398.1 - 6.4e-49 165.5 0.0 9.7e-49 164.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CEP08398.1 - 7.6e-19 66.5 1.1 1.5e-18 65.6 0.7 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CEP08398.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 SLBB domain RepA_C PF04796.7 CEP08399.1 - 0.0083 15.7 1.2 0.021 14.4 0.9 1.6 1 0 0 1 1 1 1 Plasmid encoded RepA protein NIR_SIR PF01077.17 CEP08400.1 - 6.2e-49 165.3 0.0 6.4e-44 149.0 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 CEP08400.1 - 2.4e-30 105.4 0.0 5.9e-30 104.1 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.12 CEP08400.1 - 1.8e-27 94.7 0.1 1.3e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.14 CEP08400.1 - 3e-17 62.9 0.2 8.4e-17 61.4 0.2 1.7 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.2 CEP08400.1 - 0.0026 17.7 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 CEP08400.1 - 0.009 15.4 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 CEP08400.1 - 0.042 13.7 0.0 2.5 8.0 0.0 2.9 2 0 0 2 2 2 0 NrdI Flavodoxin like zf-DNL PF05180.7 CEP08401.1 - 3e-32 110.1 0.8 3e-32 110.1 0.6 2.1 3 0 0 3 3 3 1 DNL zinc finger DUF4606 PF15379.1 CEP08401.1 - 0.0089 16.0 0.2 0.029 14.4 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4606) Elf1 PF05129.8 CEP08401.1 - 0.044 13.4 0.8 0.044 13.4 0.6 2.1 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like RasGEF_N PF00618.15 CEP08401.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 RasGEF N-terminal motif DUF3795 PF12675.2 CEP08401.1 - 0.14 12.3 0.2 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) zinc_ribbon_4 PF13717.1 CEP08401.1 - 1.5 8.5 0.0 1.5 8.5 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF619 PF04768.8 CEP08402.1 - 6.4e-39 133.0 0.1 2.3e-38 131.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CEP08402.1 - 1.4e-29 102.8 0.0 3.5e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CEP08402.1 - 4.7e-25 88.5 0.0 1.1e-24 87.3 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 CEP08402.1 - 7.7e-10 38.9 0.0 1.8e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 CEP08402.1 - 0.0063 16.4 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DUF3704 PF12488.3 CEP08402.1 - 0.028 14.0 0.1 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) GFO_IDH_MocA PF01408.17 CEP08402.1 - 0.052 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 CEP08403.1 - 4.7e-114 381.3 0.0 7.1e-114 380.7 0.0 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CEP08403.1 - 8.8e-07 29.0 0.1 1.4e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 CEP08403.1 - 0.00077 19.4 0.1 0.0029 17.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CEP08403.1 - 0.0051 16.8 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEP08403.1 - 0.0082 15.4 0.1 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CEP08403.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CEP08403.1 - 0.02 15.3 0.1 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 CEP08403.1 - 0.05 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 CEP08403.1 - 0.058 13.6 0.2 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Cpn60_TCP1 PF00118.19 CEP08404.1 - 1.9e-118 396.1 6.6 2.2e-118 395.9 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C2H2_jaz PF12171.3 CEP08405.1 - 0.047 13.8 4.5 5.7 7.2 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CEP08405.1 - 0.062 13.6 17.5 0.24 11.8 0.4 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP08405.1 - 0.097 13.0 15.2 0.13 12.6 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP08405.1 - 0.54 10.6 0.2 0.54 10.6 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain UDPGT PF00201.13 CEP08406.1 - 7.4e-16 57.7 0.1 8.2e-14 51.0 0.0 2.8 2 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 CEP08406.1 - 5.5e-06 25.8 0.0 0.021 14.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 CEP08406.1 - 0.00044 19.9 0.0 0.00087 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain zf-C2H2_2 PF12756.2 CEP08407.1 - 6.3e-40 135.3 11.9 3.4e-31 107.3 0.1 3.6 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CEP08407.1 - 6.3e-12 45.2 10.8 2.4e-09 37.0 4.0 4.1 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP08407.1 - 1.9e-08 34.2 10.8 3e-07 30.3 2.9 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-DBF PF07535.7 CEP08407.1 - 0.00089 18.8 0.7 0.00089 18.8 0.5 3.2 3 1 0 3 3 3 1 DBF zinc finger zf-LYAR PF08790.6 CEP08407.1 - 0.016 14.9 5.2 0.42 10.3 0.1 2.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Glyco_tran_WbsX PF14307.1 CEP08407.1 - 0.11 11.7 3.3 0.17 11.0 2.3 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX zf-C2H2_6 PF13912.1 CEP08407.1 - 1.1 9.2 6.6 2 8.4 1.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PSCyt3 PF07627.6 CEP08407.1 - 1.4 8.7 4.8 0.36 10.6 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1588) AKAP95 PF04988.7 CEP08407.1 - 1.8 8.2 14.2 2.6 7.7 0.5 3.6 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CEP08407.1 - 3.8 8.0 19.5 1 9.8 0.8 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger MFS_1 PF07690.11 CEP08408.1 - 1.1e-36 126.2 74.0 7.4e-31 107.1 32.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP08408.1 - 1.3e-06 27.3 13.2 1.3e-06 27.3 9.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter APC_CDC26 PF10471.4 CEP08409.1 - 2 9.2 7.6 5.1 7.8 5.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Glyco_hydro_18 PF00704.23 CEP08410.1 - 2.4e-65 221.2 3.5 2.8e-65 221.0 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC1 PF03109.11 CEP08411.1 - 2.1e-29 101.9 0.1 4.6e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 ABC1 family CPSase_L_D2 PF02786.12 CEP08412.1 - 7.8e-66 221.3 0.0 1.7e-65 220.2 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CEP08412.1 - 2.6e-39 133.7 0.0 4.8e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CEP08412.1 - 4.2e-37 126.4 0.0 1.5e-35 121.4 0.0 2.8 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain SGS PF05002.10 CEP08412.1 - 6e-29 99.6 1.0 1.3e-28 98.5 0.7 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CEP08412.1 - 9.9e-16 58.0 0.8 4.2e-15 56.0 0.3 2.3 2 0 0 2 2 2 1 CS domain TPR_11 PF13414.1 CEP08412.1 - 1.7e-11 43.6 1.1 4.2e-07 29.5 0.2 2.6 2 0 0 2 2 2 2 TPR repeat ATP-grasp_4 PF13535.1 CEP08412.1 - 1.1e-09 38.2 0.3 3.5e-09 36.6 0.0 1.9 2 0 0 2 2 1 1 ATP-grasp domain TPR_2 PF07719.12 CEP08412.1 - 2.4e-09 36.3 3.2 0.00048 19.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP08412.1 - 2.3e-08 34.2 0.4 0.002 18.4 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Dala_Dala_lig_C PF07478.8 CEP08412.1 - 3.1e-08 33.2 0.0 8.6e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 CEP08412.1 - 2.9e-06 26.8 0.0 7.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme TPR_16 PF13432.1 CEP08412.1 - 5.6e-06 26.8 1.5 0.0064 17.1 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP08412.1 - 5.7e-06 26.4 0.4 0.52 11.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP08412.1 - 6e-06 25.6 0.3 0.00093 18.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ATP-grasp PF02222.17 CEP08412.1 - 2.9e-05 23.4 0.0 8.7e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain TPR_12 PF13424.1 CEP08412.1 - 7.8e-05 22.5 4.5 0.00068 19.5 1.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat ATP-grasp_3 PF02655.9 CEP08412.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain TPR_9 PF13371.1 CEP08412.1 - 0.00016 21.4 0.4 0.013 15.3 0.4 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CEP08412.1 - 0.00048 20.2 0.3 0.0011 19.0 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CEP08412.1 - 0.0032 17.1 1.4 8.2 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CEP08412.1 - 0.0069 16.7 1.2 0.042 14.2 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP08412.1 - 0.033 13.9 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.14 CEP08412.1 - 0.035 13.2 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_10 PF13374.1 CEP08412.1 - 0.11 12.4 3.7 0.84 9.6 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat UMP1 PF05348.6 CEP08413.1 - 1.5e-33 115.5 0.2 1.7e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MS_channel PF00924.13 CEP08414.1 - 7.2e-09 35.2 0.9 1.5e-08 34.1 0.6 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CEP08414.1 - 0.0005 19.1 0.1 0.0013 17.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CEP08414.1 - 0.0015 18.2 0.1 0.0044 16.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain Cytokin_check_N PF10407.4 CEP08414.1 - 0.0042 16.6 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus EF-hand_5 PF13202.1 CEP08414.1 - 0.0046 16.2 0.1 0.013 14.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CEP08414.1 - 0.024 14.7 0.1 0.058 13.5 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair ABC2_membrane_2 PF12679.2 CEP08414.1 - 0.024 13.4 2.8 0.74 8.6 0.0 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3808 PF10300.4 CEP08414.1 - 0.064 11.8 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) CTNNBL PF08216.6 CEP08415.1 - 0.0094 15.5 0.3 0.019 14.5 0.1 1.5 1 1 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear SOXp PF12336.3 CEP08415.1 - 0.34 11.5 7.3 0.18 12.4 3.1 1.9 1 1 1 2 2 2 0 SOX transcription factor DUF4611 PF15387.1 CEP08415.1 - 0.99 9.5 6.4 1.7 8.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) MIR PF02815.14 CEP08419.1 - 0.028 13.9 0.2 0.077 12.5 0.1 1.7 1 0 0 1 1 1 0 MIR domain Cyclin PF08613.6 CEP08420.1 - 1.9e-12 47.8 0.1 3.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP08420.1 - 1.9e-11 43.6 0.2 2.9e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-CCCH PF00642.19 CEP08421.1 - 6.9e-19 67.0 34.4 8.3e-05 22.1 0.2 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 CEP08421.1 - 7.4e-06 25.6 3.2 7.4e-06 25.6 2.2 2.9 3 0 0 3 3 3 1 Zinc knuckle zf-CCCH_2 PF14608.1 CEP08421.1 - 1.4e-05 24.8 46.2 0.0085 16.0 3.3 6.2 6 1 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHC_2 PF13696.1 CEP08421.1 - 0.3 10.6 6.7 0.11 12.0 1.0 2.8 3 0 0 3 3 3 0 Zinc knuckle Per1 PF04080.8 CEP08422.1 - 7.1e-96 320.7 8.9 1.3e-95 319.8 6.2 1.5 1 0 0 1 1 1 1 Per1-like NAD_binding_8 PF13450.1 CEP08422.1 - 5.4e-14 51.9 0.0 1.5e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CEP08422.1 - 0.00032 20.8 0.1 0.75 9.8 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP08422.1 - 0.0024 16.8 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CEP08422.1 - 0.0038 17.0 0.6 0.31 10.8 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEP08422.1 - 0.0091 15.8 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CEP08422.1 - 0.022 13.6 0.1 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CEP08422.1 - 0.16 10.3 0.1 3.8 5.8 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 CEP08422.1 - 0.19 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Band_7 PF01145.20 CEP08423.1 - 3e-24 85.8 3.5 4.5e-24 85.3 2.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 CEP08423.1 - 0.05 13.0 0.6 0.17 11.3 0.2 1.8 1 1 1 2 2 2 0 Enhancer of Polycomb C-terminus Translin PF01997.11 CEP08424.1 - 8.2e-42 143.0 0.2 9.7e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Translin family BLOC1_2 PF10046.4 CEP08424.1 - 0.014 15.5 1.7 3.3 7.9 0.0 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GMP_synt_C PF00958.17 CEP08424.1 - 0.015 14.9 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 GMP synthase C terminal domain DUF1479 PF07350.7 CEP08424.1 - 0.023 13.2 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Syntaxin-6_N PF09177.6 CEP08424.1 - 0.045 14.1 2.6 4 7.9 0.2 3.1 2 1 0 3 3 3 0 Syntaxin 6, N-terminal Gpi1 PF05024.10 CEP08424.1 - 0.07 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) DUF948 PF06103.6 CEP08424.1 - 0.47 10.3 3.9 13 5.7 0.0 3.2 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MHYT PF03707.11 CEP08425.1 - 4.8e-14 52.2 19.8 2.7e-05 24.1 0.9 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat DUF4131 PF13567.1 CEP08425.1 - 6.2 6.1 12.6 7.4 5.9 0.8 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) TPR_1 PF00515.23 CEP08426.1 - 0.066 12.8 2.4 0.17 11.5 0.6 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP08426.1 - 0.11 12.1 2.0 0.33 10.6 0.0 2.6 2 1 0 2 2 2 0 TPR repeat Sigma70_ner PF04546.8 CEP08427.1 - 0.009 15.6 3.0 0.012 15.2 2.1 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region zf-C2H2_2 PF12756.2 CEP08427.1 - 0.052 13.6 1.6 0.22 11.6 1.1 2.0 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RAB3GAP2_C PF14656.1 CEP08427.1 - 0.1 10.7 0.2 0.14 10.2 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF1188 PF06690.6 CEP08427.1 - 0.15 11.1 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) RRM_1 PF00076.17 CEP08428.1 - 2.8e-16 58.9 0.2 4.5e-16 58.2 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP08428.1 - 1.5e-13 50.5 0.0 2.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP08428.1 - 1.8e-08 34.1 0.1 2.6e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-1a PF01176.14 CEP08429.1 - 1e-27 95.3 0.2 1.4e-27 94.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 zf-RVT PF13966.1 CEP08430.1 - 1.1e-07 32.0 1.0 2e-07 31.1 0.7 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase UPF0147 PF03685.8 CEP08431.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) HEAT_2 PF13646.1 CEP08433.1 - 1.1e-11 44.7 9.5 0.0095 16.1 0.0 6.7 5 2 2 7 7 7 4 HEAT repeats HEAT PF02985.17 CEP08433.1 - 8.5e-09 34.7 14.4 1.2 9.4 0.0 8.4 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 CEP08433.1 - 0.0076 16.7 13.6 0.12 12.8 0.1 6.5 6 0 0 6 6 6 1 HEAT-like repeat Ipi1_N PF12333.3 CEP08433.1 - 0.064 13.2 6.2 0.76 9.7 0.1 5.1 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 CEP08433.1 - 0.15 11.9 5.5 1.9 8.4 0.1 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF533 PF04391.7 CEP08434.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF1308 PF07000.6 CEP08437.1 - 0.012 14.3 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) HTH_WhiA PF02650.9 CEP08437.1 - 0.034 14.5 1.5 0.034 14.5 1.0 1.6 2 0 0 2 2 2 0 WhiA C-terminal HTH domain RE_TdeIII PF09520.5 CEP08438.1 - 0.058 12.6 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Type II restriction endonuclease, TdeIII UCH PF00443.24 CEP08439.1 - 1.2e-47 162.2 1.1 2.9e-47 161.0 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP08439.1 - 5.8e-20 71.9 2.6 5.8e-20 71.9 1.8 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CEP08439.1 - 0.00051 20.3 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.15 CEP08439.1 - 0.012 15.1 0.1 0.03 13.8 0.1 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-trcl PF13451.1 CEP08439.1 - 0.84 9.3 4.1 0.2 11.2 0.4 1.9 2 0 0 2 2 2 0 Probable zinc-binding domain RVT_1 PF00078.22 CEP08440.1 - 3.8e-18 65.6 0.1 7.8e-18 64.6 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 CEP08441.1 - 1.5e-06 27.9 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP08441.1 - 2.5e-05 25.0 0.0 8.9e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP08441.1 - 0.00064 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 CEP08441.1 - 0.00095 18.5 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.1 CEP08441.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP08441.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_psq PF05225.11 CEP08441.1 - 0.0085 15.6 0.0 0.026 14.0 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_7 PF02796.10 CEP08441.1 - 0.011 15.5 0.0 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MerR_1 PF13411.1 CEP08441.1 - 0.1 12.3 0.3 0.45 10.3 0.1 2.2 1 1 1 2 2 2 0 MerR HTH family regulatory protein HTH_Tnp_Tc5 PF03221.11 CEP08442.1 - 1.1e-08 34.7 0.0 2.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 CEP08442.1 - 0.00033 20.0 0.1 0.0036 16.6 0.1 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.1 CEP08442.1 - 0.034 14.9 0.0 0.097 13.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain RVT_1 PF00078.22 CEP08443.1 - 5.1e-10 39.0 0.0 7.1e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP08446.1 - 4.2e-13 49.1 0.0 5.2e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rap_GAP PF02145.10 CEP08447.1 - 1.3e-20 73.5 0.1 4.3e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Rap/ran-GAP DUF1670 PF07900.6 CEP08447.1 - 0.012 14.8 1.2 0.022 13.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) Bac_surface_Ag PF01103.18 CEP08448.1 - 2.4e-46 158.7 0.4 3e-46 158.3 0.3 1.1 1 0 0 1 1 1 1 Surface antigen Ribosomal_L19 PF01245.15 CEP08448.1 - 0.048 13.4 0.2 0.24 11.1 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein L19 tRNA-synt_His PF13393.1 CEP08448.1 - 0.074 12.0 1.6 0.11 11.5 1.1 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Nop14 PF04147.7 CEP08449.1 - 9.1e-246 817.8 44.7 1.1e-245 817.5 31.0 1.0 1 0 0 1 1 1 1 Nop14-like family bZIP_1 PF00170.16 CEP08450.1 - 7.5e-10 38.6 12.0 7.5e-10 38.6 8.4 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP08450.1 - 5.6e-06 26.0 11.4 5.6e-06 26.0 7.9 1.7 2 0 0 2 2 2 1 Basic region leucine zipper Speriolin_N PF15058.1 CEP08450.1 - 0.0037 17.2 0.2 0.0037 17.2 0.2 2.1 2 0 0 2 2 2 1 Speriolin N terminus bZIP_Maf PF03131.12 CEP08450.1 - 0.39 11.0 9.9 0.25 11.6 4.6 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor Metallophos PF00149.23 CEP08451.1 - 5.2e-11 42.3 3.5 1e-10 41.3 2.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase B12-binding PF02310.14 CEP08451.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain GDA1_CD39 PF01150.12 CEP08452.1 - 4.7e-95 318.6 0.0 5.3e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pkinase PF00069.20 CEP08453.1 - 7.5e-71 238.3 0.0 1.2e-70 237.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08453.1 - 4.3e-35 121.0 0.0 1.2e-34 119.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP08453.1 - 0.0002 20.4 1.1 0.041 12.8 0.0 3.1 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.17 CEP08453.1 - 0.046 13.0 1.0 0.22 10.8 0.7 2.0 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.9 CEP08453.1 - 0.093 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 4HBT_2 PF13279.1 CEP08454.1 - 6.9e-11 42.6 0.1 1.2e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 CEP08454.1 - 0.0079 15.1 3.5 0.014 14.3 2.4 1.5 1 1 1 2 2 2 1 Acyl-ACP thioesterase Lactamase_B PF00753.22 CEP08455.1 - 7e-21 74.7 1.9 9.3e-21 74.3 0.7 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CEP08455.1 - 6.5e-08 32.3 0.2 1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AhpC-TSA PF00578.16 CEP08456.1 - 9.4e-38 128.6 0.0 2.1e-37 127.5 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CEP08456.1 - 1.7e-15 56.8 0.0 2.2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CEP08456.1 - 3.8e-13 48.8 0.1 7.4e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin KTI12 PF08433.5 CEP08457.1 - 1.1e-82 277.2 0.0 9e-82 274.3 0.0 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CEP08457.1 - 1.5e-06 28.0 0.0 1.5e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP08457.1 - 0.038 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Pribosyltran PF00156.22 CEP08458.1 - 7.1e-09 35.4 0.0 1.9e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain adh_short PF00106.20 CEP08459.1 - 8.2e-31 107.1 0.3 1.1e-30 106.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP08459.1 - 2.5e-27 96.2 0.4 5.1e-27 95.1 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP08459.1 - 6.4e-16 58.5 0.1 9.3e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 CEP08459.1 - 1.5e-05 24.8 0.2 2.4e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 CEP08459.1 - 0.012 15.3 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IGPD PF00475.13 CEP08460.1 - 1.8e-62 209.4 0.6 2.4e-62 209.0 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase TRAM_LAG1_CLN8 PF03798.11 CEP08461.1 - 1.6e-40 138.8 25.4 1.6e-40 138.8 17.6 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CEP08461.1 - 1.7e-17 62.6 1.1 1.7e-17 62.6 0.7 2.6 2 0 0 2 2 2 1 TRAM1-like protein DUF4083 PF13314.1 CEP08461.1 - 0.15 11.8 0.1 0.15 11.8 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) TPP_enzyme_N PF02776.13 CEP08462.1 - 4.6e-29 101.0 0.1 1.3e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CEP08462.1 - 5.2e-21 74.8 0.0 1.2e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CEP08462.1 - 1.4e-17 63.7 0.0 2.9e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 CEP08462.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit RVT_1 PF00078.22 CEP08463.1 - 9.1e-07 28.4 0.1 3.6e-06 26.5 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CEP08464.1 - 1.9e-06 27.5 15.3 0.0064 16.3 3.4 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP08464.1 - 0.0081 15.8 1.3 0.0081 15.8 0.9 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CHC2 PF01807.15 CEP08464.1 - 0.088 12.3 0.1 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 CHC2 zinc finger zf-CCHC_2 PF13696.1 CEP08464.1 - 0.17 11.3 10.1 0.75 9.3 1.4 2.5 1 1 1 2 2 2 0 Zinc knuckle RE_LlaJI PF09563.5 CEP08466.1 - 0.015 13.9 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 LlaJI restriction endonuclease DUF2777 PF10949.3 CEP08466.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) UDG PF03167.14 CEP08466.1 - 0.093 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily MRP-S27 PF10037.4 CEP08467.1 - 0.0077 15.2 0.2 0.0095 14.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Baculo_PEP_C PF04513.7 CEP08467.1 - 0.032 14.0 1.3 0.072 12.9 0.8 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Effector_1 PF04518.7 CEP08467.1 - 0.061 12.2 1.4 0.38 9.6 0.4 1.8 1 1 1 2 2 2 0 Effector from type III secretion system DivIVA PF05103.8 CEP08467.1 - 0.074 13.1 1.4 0.087 12.8 1.0 1.1 1 0 0 1 1 1 0 DivIVA protein LTXXQ PF07813.7 CEP08467.1 - 0.079 13.4 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 LTXXQ motif family protein Borrelia_lipo_1 PF05714.6 CEP08467.1 - 0.084 11.9 1.4 0.11 11.5 1.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF241 PF03087.9 CEP08468.1 - 0.83 9.0 5.6 1.4 8.3 3.9 1.3 1 1 0 1 1 1 0 Arabidopsis protein of unknown function MFS_1 PF07690.11 CEP08471.1 - 1.1e-34 119.6 19.7 1.1e-34 119.6 13.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily IncA PF04156.9 CEP08471.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 IncA protein YCII PF03795.9 CEP08472.1 - 7.5e-12 45.2 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 YCII-related domain YlbD_coat PF14071.1 CEP08472.1 - 0.46 10.5 5.1 0.11 12.5 0.6 2.0 2 1 0 2 2 2 0 Putative coat protein Exo_endo_phos_2 PF14529.1 CEP08474.1 - 3.1e-07 30.0 1.2 0.00052 19.6 0.0 3.5 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP08474.1 - 0.0015 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1604 PF07713.8 CEP08476.1 - 1.5e-37 127.2 2.9 1.5e-37 127.2 2.0 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF1604) G-patch PF01585.18 CEP08476.1 - 2.3e-09 36.8 0.0 9.6e-09 34.8 0.0 2.1 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CEP08476.1 - 0.0017 18.1 0.0 0.0017 18.1 0.0 3.7 3 0 0 3 3 3 1 DExH-box splicing factor binding site Asp_protease_2 PF13650.1 CEP08477.1 - 1.5e-06 28.6 0.1 4e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP08477.1 - 0.00068 19.5 0.8 0.0018 18.1 0.5 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP08477.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 CEP08477.1 - 0.011 15.3 0.1 0.025 14.1 0.1 1.6 1 1 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 CEP08477.1 - 0.034 14.0 1.2 0.08 12.8 0.7 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A2B PF12384.3 CEP08477.1 - 0.22 10.8 4.0 0.1 11.9 0.8 1.8 2 0 0 2 2 2 0 Ty3 transposon peptidase DUF950 PF06106.6 CEP08478.1 - 0.11 12.5 0.1 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Staphylococcus protein of unknown function (DUF950) HEAT_2 PF13646.1 CEP08479.1 - 0.1 12.8 0.1 4.2 7.7 0.0 2.9 3 0 0 3 3 3 0 HEAT repeats COXG PF06240.8 CEP08479.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) zf-RVT PF13966.1 CEP08480.1 - 0.00096 19.4 0.3 0.002 18.4 0.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF3576 PF12100.3 CEP08481.1 - 0.025 14.6 0.2 0.097 12.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3576) Fungal_trans PF04082.13 CEP08482.1 - 2.1e-26 92.3 0.7 4.6e-26 91.2 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP08482.1 - 1.5e-08 34.3 13.3 2.8e-08 33.5 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 CEP08482.1 - 1.2 7.2 22.3 0.13 10.5 11.0 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2802 PF10975.3 CEP08482.1 - 4.8 7.0 15.7 70 3.2 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) WD40 PF00400.27 CEP08483.1 - 1.3e-31 107.3 11.1 7.6e-08 31.9 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CEP08483.1 - 5.5e-06 24.8 0.0 0.021 12.9 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 CEP08483.1 - 0.0019 17.0 0.2 0.0031 16.3 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region BBS2_Mid PF14783.1 CEP08483.1 - 0.0078 15.9 0.2 0.22 11.3 0.1 3.2 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Hira PF07569.6 CEP08483.1 - 0.082 12.1 0.1 0.88 8.7 0.0 2.4 2 1 0 2 2 2 0 TUP1-like enhancer of split ABC_membrane PF00664.18 CEP08484.1 - 1.9e-45 155.4 30.1 5.3e-26 91.6 7.4 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP08484.1 - 1.3e-43 148.5 0.6 7.8e-29 100.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 CEP08484.1 - 2.5e-07 30.1 3.7 0.003 16.8 1.6 3.7 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 CEP08484.1 - 5e-06 25.6 0.0 0.015 14.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 CEP08484.1 - 4.3e-05 23.0 0.1 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 CEP08484.1 - 0.00013 21.8 0.5 0.4 10.4 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_29 PF13555.1 CEP08484.1 - 0.00078 18.9 1.5 0.27 10.7 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 CEP08484.1 - 0.003 17.4 0.6 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 CEP08484.1 - 0.0048 16.8 0.5 0.68 9.8 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 CEP08484.1 - 0.0073 15.4 0.2 1.5 7.8 0.0 2.8 2 0 0 2 2 2 1 KaiC TrwB_AAD_bind PF10412.4 CEP08484.1 - 0.0088 14.7 0.2 2.4 6.6 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 CEP08484.1 - 0.01 15.3 0.2 5 6.5 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 CEP08484.1 - 0.012 15.0 0.6 0.93 8.8 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 CEP08484.1 - 0.017 15.2 1.2 6.1 6.9 0.1 3.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CEP08484.1 - 0.023 15.0 7.1 0.16 12.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.4 CEP08484.1 - 0.038 12.9 1.5 1.1 8.1 0.0 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 CEP08484.1 - 0.066 12.6 0.0 3.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Zot PF05707.7 CEP08484.1 - 0.17 11.3 0.1 8.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 CEP08484.1 - 0.38 11.5 4.8 1.2 9.9 0.8 3.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CEP08484.1 - 3.5 7.9 5.2 2.3 8.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Ribosomal_L23eN PF03939.8 CEP08485.1 - 3.9e-20 71.6 7.9 3.9e-20 71.6 5.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 CEP08485.1 - 5.1e-19 67.9 4.1 5.3e-19 67.9 1.4 2.0 2 1 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.6 CEP08485.1 - 0.06 13.2 0.1 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DUF1323 PF07037.6 CEP08485.1 - 0.094 12.8 0.2 0.2 11.8 0.1 1.6 1 1 1 2 2 2 0 Putative transcription regulator (DUF1323) Tubulin PF00091.20 CEP08485.1 - 0.095 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Ribosomal_L7Ae PF01248.21 CEP08486.1 - 5.7e-28 96.2 2.2 7.2e-28 95.9 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S7e PF01251.13 CEP08487.1 - 3.9e-81 271.0 0.4 4.4e-81 270.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Sel1 PF08238.7 CEP08488.1 - 8.9e-126 407.6 64.3 1.3e-11 44.7 0.3 15.5 16 0 0 16 16 16 14 Sel1 repeat TPR_6 PF13174.1 CEP08488.1 - 6.3e-06 26.2 12.7 0.76 10.3 0.1 8.4 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEP08488.1 - 0.0074 15.9 41.3 1.7 8.3 2.2 8.2 2 1 6 8 8 8 6 TPR repeat TPR_17 PF13431.1 CEP08488.1 - 0.0088 16.1 15.1 25 5.3 0.5 9.0 9 1 1 10 10 10 1 Tetratricopeptide repeat ERG4_ERG24 PF01222.12 CEP08489.1 - 1.2e-142 475.4 15.4 1.4e-142 475.2 10.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 CEP08489.1 - 0.034 14.2 0.0 0.034 14.2 0.0 3.1 3 1 0 3 3 3 0 Phospholipid methyltransferase Ribosomal_L11_N PF03946.9 CEP08490.1 - 1e-17 63.2 0.1 2.1e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CEP08490.1 - 2.9e-11 43.3 0.1 6.6e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain EF-hand_1 PF00036.27 CEP08490.1 - 4.5e-07 28.6 0.4 4.5e-07 28.6 0.2 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CEP08490.1 - 6.9e-07 28.6 2.1 5.1e-06 25.9 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 CEP08490.1 - 2.3e-06 27.6 2.7 5.2e-06 26.4 0.1 2.7 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.1 CEP08490.1 - 6.3e-06 25.2 0.2 2.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CEP08490.1 - 0.0018 17.8 0.6 0.008 15.7 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.2 CEP08490.1 - 0.2 11.4 1.2 0.9 9.3 0.1 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Macoilin PF09726.4 CEP08490.1 - 0.37 9.0 9.5 0.44 8.7 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Mcm10 PF09332.6 CEP08490.1 - 0.63 9.3 7.5 0.96 8.7 5.2 1.4 1 0 0 1 1 1 0 Mcm10 replication factor DNA_pol_viral_N PF00242.12 CEP08490.1 - 1.5 7.7 11.1 2.5 7.0 7.7 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ADH_zinc_N PF00107.21 CEP08491.1 - 1.3e-24 86.2 0.1 2.4e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP08491.1 - 6.6e-15 56.1 0.1 2.1e-14 54.4 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP08491.1 - 3.3e-10 39.6 0.0 1.1e-09 38.0 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Peptidase_M24 PF00557.19 CEP08492.1 - 4.4e-58 196.2 0.1 7e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CEP08492.1 - 1.7e-25 88.9 0.0 3.1e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.2 CEP08492.1 - 0.079 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) TPR_1 PF00515.23 CEP08494.1 - 1.1e-50 167.1 39.4 4.6e-08 32.3 0.0 11.3 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 CEP08494.1 - 2.7e-45 151.8 31.1 8.3e-12 44.5 0.3 6.9 3 2 4 7 7 7 7 TPR repeat TPR_2 PF07719.12 CEP08494.1 - 9.7e-45 146.9 34.1 6.9e-06 25.5 0.0 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 CEP08494.1 - 1.3e-30 105.4 19.1 1.3e-08 35.2 0.1 7.1 5 1 3 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 CEP08494.1 - 1.6e-30 104.8 29.6 2e-06 27.6 0.4 6.7 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 CEP08494.1 - 5.5e-30 100.8 35.4 3.1e-05 23.4 2.1 10.2 8 2 2 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 CEP08494.1 - 1.2e-29 99.9 26.1 0.00036 20.4 0.1 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 CEP08494.1 - 6.9e-25 85.2 15.0 0.0027 18.2 0.0 10.0 4 2 7 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 CEP08494.1 - 2.3e-23 82.2 19.6 1.4e-05 25.2 0.3 7.3 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 CEP08494.1 - 1.1e-20 71.6 21.4 0.0053 16.4 0.4 9.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.1 CEP08494.1 - 5.4e-18 64.1 28.7 0.00064 20.0 0.0 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 CEP08494.1 - 1.6e-16 59.9 15.0 0.00059 19.6 0.0 6.5 4 2 3 7 7 7 6 Tetratricopeptide repeat Apc3 PF12895.2 CEP08494.1 - 3.8e-11 42.9 21.6 5.3e-06 26.4 2.8 4.5 3 2 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CEP08494.1 - 1.4e-08 34.1 14.5 0.0038 16.3 2.5 4.5 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 CEP08494.1 - 0.53 10.2 0.0 0.53 10.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.13 CEP08494.1 - 2.1 8.3 25.2 3.5 7.5 0.2 6.8 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain Tetraspannin PF00335.15 CEP08495.1 - 3.3e-15 55.9 4.4 3.3e-15 55.9 3.0 2.8 3 1 0 3 3 3 1 Tetraspanin family EI24 PF07264.6 CEP08495.1 - 9.1e-11 41.5 23.5 9.1e-11 41.5 16.3 2.6 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) PAP2 PF01569.16 CEP08496.1 - 3.3e-08 33.2 2.6 5.2e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 CEP08496.1 - 0.077 12.7 0.1 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Divergent PAP2 family DUF1430 PF07242.6 CEP08496.1 - 0.19 11.7 3.2 7.7 6.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) PUF PF00806.14 CEP08497.1 - 6.5e-62 201.6 16.8 2.2e-10 39.3 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.19 CEP08497.1 - 0.0002 20.9 0.8 0.00048 19.7 0.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rabaptin PF03528.10 CEP08497.1 - 0.069 13.0 9.3 0.063 13.1 2.3 3.0 3 0 0 3 3 3 0 Rabaptin MFS_1 PF07690.11 CEP08498.1 - 5.1e-32 110.9 62.2 4.1e-25 88.2 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP08498.1 - 2.2e-15 56.0 15.3 2.2e-15 56.0 10.6 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 CEP08498.1 - 0.0002 21.0 3.8 0.00053 19.7 0.0 3.1 2 1 1 3 3 3 1 MFS_1 like family DUF695 PF05117.7 CEP08498.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF695) GMC_oxred_N PF00732.14 CEP08499.1 - 3e-66 223.5 0.0 4e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEP08499.1 - 3.1e-32 111.8 0.0 5.2e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CEP08499.1 - 2.7e-05 24.1 0.2 0.00011 22.1 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEP08499.1 - 7.2e-05 21.8 0.6 0.003 16.5 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP08499.1 - 0.00038 19.4 0.1 0.00082 18.3 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CEP08499.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP08499.1 - 0.0026 16.7 0.1 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CEP08499.1 - 0.0075 15.3 0.1 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CEP08499.1 - 0.018 13.9 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 CEP08499.1 - 0.034 14.5 0.7 0.098 13.0 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEP08499.1 - 0.046 12.1 0.0 0.082 11.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 CEP08499.1 - 0.056 12.0 0.0 0.093 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 CEP08499.1 - 0.11 12.5 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.2 CEP08499.1 - 0.18 10.8 0.3 0.37 9.8 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase IDO PF01231.13 CEP08500.1 - 1.5e-51 175.1 0.0 2.1e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DPBB_1 PF03330.13 CEP08501.1 - 7.7e-09 35.4 0.0 9.9e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel PAS PF00989.19 CEP08502.1 - 0.00014 21.5 0.8 0.001 18.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold Suf PF05843.9 CEP08502.1 - 0.036 13.8 7.2 0.057 13.1 5.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CEP08502.1 - 0.11 12.4 13.8 0.14 11.9 9.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex16 PF08610.5 CEP08502.1 - 0.63 8.9 7.1 1.1 8.2 5.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PAT1 PF09770.4 CEP08502.1 - 1.3 7.1 26.6 1.7 6.7 18.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Auxin_canalis PF05703.6 CEP08502.1 - 8.3 6.1 10.1 0.18 11.5 1.6 2.0 2 0 0 2 2 2 0 Auxin canalisation DDE_3 PF13358.1 CEP08503.1 - 6.2e-07 29.2 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Mito_carr PF00153.22 CEP08504.1 - 3.5e-59 196.5 3.4 1.1e-19 69.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3816 PF12822.2 CEP08504.1 - 0.043 13.7 1.2 0.12 12.2 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3816) DUF1906 PF08924.6 CEP08505.1 - 0.059 13.2 0.6 0.18 11.6 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Daxx PF03344.10 CEP08505.1 - 0.075 11.5 35.4 0.11 10.9 24.5 1.2 1 0 0 1 1 1 0 Daxx Family FAM60A PF15396.1 CEP08505.1 - 6.7 6.3 29.2 0.83 9.3 3.2 2.4 2 0 0 2 2 2 0 Protein Family FAM60A NTP_transferase PF00483.18 CEP08506.1 - 5.9e-18 65.0 0.0 8.3e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CEP08506.1 - 5.3e-09 36.3 0.0 7.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Pox_D5 PF03288.11 CEP08506.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF4430 PF14478.1 CEP08507.1 - 0.0052 16.7 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Glyco_hydro_8 PF01270.12 CEP08508.1 - 5.2e-46 156.9 0.1 6.8e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 MPLKIP PF15502.1 CEP08509.1 - 0.00022 21.9 13.7 0.00042 21.0 9.5 1.5 1 1 0 1 1 1 1 M-phase-specific PLK1-interacting protein LSM PF01423.17 CEP08510.1 - 3.3e-09 36.1 0.2 3.9e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEP08510.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Septin PF00735.13 CEP08511.1 - 8.2e-112 372.8 0.3 9.9e-112 372.5 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEP08511.1 - 1e-07 31.8 0.0 2e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP08511.1 - 2.4e-07 30.0 0.0 4.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CEP08511.1 - 3e-06 26.4 0.0 5.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_10 PF12846.2 CEP08511.1 - 7.7e-05 22.2 0.7 0.00027 20.4 0.5 1.9 1 1 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 CEP08511.1 - 0.00012 21.5 0.1 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CEP08511.1 - 0.00037 20.3 1.0 0.58 9.9 0.3 2.5 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.1 CEP08511.1 - 0.0012 18.9 0.0 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.7 CEP08511.1 - 0.0014 17.7 0.1 0.0066 15.6 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 CEP08511.1 - 0.0024 17.4 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family NB-ARC PF00931.17 CEP08511.1 - 0.0024 16.7 0.7 0.0039 16.0 0.1 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 CEP08511.1 - 0.0031 17.6 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.2 CEP08511.1 - 0.0035 16.4 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region D3 AAA_17 PF13207.1 CEP08511.1 - 0.0042 17.8 0.8 1.3 9.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CEP08511.1 - 0.0045 16.8 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CEP08511.1 - 0.0046 17.2 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 CEP08511.1 - 0.0046 17.4 0.0 0.0091 16.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF815 PF05673.8 CEP08511.1 - 0.0063 15.4 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) T2SE PF00437.15 CEP08511.1 - 0.012 14.5 0.1 0.033 13.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 CEP08511.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 CEP08511.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Ras family AAA_33 PF13671.1 CEP08511.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 CEP08511.1 - 0.077 11.8 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 CEP08511.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CEP08511.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 CEP08511.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 CEP08511.1 - 0.12 11.4 0.2 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus HisG PF01634.13 CEP08512.1 - 5.9e-49 165.7 0.3 1e-48 165.0 0.2 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CEP08512.1 - 7.3e-27 93.1 0.6 1.8e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.6 CEP08512.1 - 7.3e-06 25.7 0.1 9.7e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like UreF PF01730.11 CEP08513.1 - 8.4e-12 45.4 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 UreF Aldo_ket_red PF00248.16 CEP08514.1 - 3e-09 36.1 0.0 3.9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Redoxin PF08534.5 CEP08514.1 - 0.039 13.5 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 Redoxin Mg_trans_NIPA PF05653.9 CEP08515.1 - 1.8e-82 276.7 22.6 2.1e-82 276.4 15.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CEP08515.1 - 2.5e-06 27.5 8.1 2.5e-06 27.5 5.6 3.3 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 CEP08515.1 - 0.00032 20.8 3.9 0.00032 20.8 2.7 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF2973 PF11189.3 CEP08515.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Tropomyosin_1 PF12718.2 CEP08517.1 - 0.012 15.4 10.9 0.012 15.4 7.6 3.7 1 1 2 3 3 3 0 Tropomyosin like DUF745 PF05335.8 CEP08517.1 - 0.013 14.9 2.0 0.013 14.9 1.4 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF745) Filament PF00038.16 CEP08517.1 - 0.014 14.9 38.6 0.018 14.5 26.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein Laminin_II PF06009.7 CEP08517.1 - 1.3 8.7 34.2 0.73 9.5 2.5 3.6 1 1 3 4 4 4 0 Laminin Domain II DUF3584 PF12128.3 CEP08517.1 - 2 5.6 46.4 29 1.7 32.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Mitofilin PF09731.4 CEP08517.1 - 3.3 6.2 36.9 4.9 5.6 25.6 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tropomyosin PF00261.15 CEP08517.1 - 3.4 6.7 49.1 0.039 13.0 6.9 2.4 1 1 1 2 2 2 0 Tropomyosin CENP-F_leu_zip PF10473.4 CEP08517.1 - 6.6 6.5 48.8 11 5.9 4.6 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 CEP08517.1 - 8 5.3 38.4 3.3 6.6 13.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3678 PF12435.3 CEP08518.1 - 0.056 13.0 1.0 4.4 6.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) HLH PF00010.21 CEP08519.1 - 7.1e-17 60.8 0.1 7.1e-17 60.8 0.1 1.9 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Fib_alpha PF08702.5 CEP08519.1 - 0.042 13.9 0.3 0.057 13.5 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ING PF12998.2 CEP08519.1 - 0.11 12.7 0.6 15 5.9 0.1 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4085 PF13315.1 CEP08519.1 - 0.13 11.6 0.6 0.67 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) MerR-DNA-bind PF09278.6 CEP08519.1 - 0.68 10.3 3.0 2.9 8.3 0.5 2.2 2 0 0 2 2 2 0 MerR, DNA binding PPR_2 PF13041.1 CEP08520.1 - 1.7e-64 213.6 19.6 1.9e-08 34.1 0.3 16.4 9 4 7 16 16 16 13 PPR repeat family PPR_3 PF13812.1 CEP08520.1 - 7.8e-37 122.4 24.9 0.00064 19.8 0.0 17.3 19 2 0 19 19 19 9 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEP08520.1 - 2.8e-28 97.0 7.6 0.00079 18.8 0.0 11.9 12 1 0 12 12 12 6 PPR repeat PPR PF01535.15 CEP08520.1 - 6.5e-22 75.9 30.1 0.031 14.2 0.0 16.0 19 0 0 19 19 19 6 PPR repeat RPM2 PF08579.6 CEP08520.1 - 3.7e-07 30.2 5.1 0.17 12.0 0.0 7.5 7 1 1 8 8 8 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.1 CEP08520.1 - 1.8e-06 28.0 1.4 13 6.7 0.0 8.8 9 2 2 11 11 11 1 Tetratricopeptide repeat zf-CCHC_4 PF14392.1 CEP08522.1 - 0.01 15.4 6.6 0.24 11.1 0.0 2.6 3 0 0 3 3 3 0 Zinc knuckle HNH PF01844.18 CEP08522.1 - 0.037 13.9 0.1 0.037 13.9 0.1 1.7 2 0 0 2 2 2 0 HNH endonuclease PLRV_ORF5 PF01690.12 CEP08524.1 - 5.4 6.0 8.0 6.3 5.8 5.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CH PF00307.26 CEP08525.1 - 5.2e-76 251.6 0.3 8.5e-19 67.6 0.1 4.4 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CEP08525.1 - 2.4e-12 46.3 0.0 0.0014 18.2 0.0 4.4 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 CEP08525.1 - 1.9e-08 34.2 1.1 6.9e-08 32.5 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CEP08525.1 - 3.1e-08 32.3 1.0 0.019 14.2 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CEP08525.1 - 3.7e-06 26.3 0.7 0.008 15.9 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CEP08525.1 - 5e-05 22.4 1.8 0.2 11.0 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CEP08525.1 - 0.0023 17.4 0.2 2 8.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair Actin PF00022.14 CEP08526.1 - 4.1e-29 101.2 0.0 5.9e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Actin CENP-F_leu_zip PF10473.4 CEP08526.1 - 3.1e-06 27.1 2.0 6.6e-06 26.0 1.4 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MreB_Mbl PF06723.8 CEP08526.1 - 1.1e-05 24.2 0.0 0.0005 18.7 0.0 2.5 2 0 0 2 2 2 1 MreB/Mbl protein FlxA PF14282.1 CEP08526.1 - 0.0047 16.8 13.9 0.011 15.6 9.6 1.5 1 0 0 1 1 1 1 FlxA-like protein AAT PF03417.11 CEP08526.1 - 0.045 13.2 1.3 0.094 12.1 0.9 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FtsA PF14450.1 CEP08526.1 - 0.095 12.5 0.9 0.66 9.8 0.1 2.4 2 0 0 2 2 2 0 Cell division protein FtsA IncA PF04156.9 CEP08526.1 - 0.35 10.4 7.2 0.59 9.7 4.6 1.6 2 0 0 2 2 2 0 IncA protein KxDL PF10241.4 CEP08526.1 - 0.47 10.3 7.4 3.8 7.4 3.9 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein SR-25 PF10500.4 CEP08526.1 - 0.62 9.4 8.2 1.1 8.6 5.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein V_ATPase_I PF01496.14 CEP08526.1 - 0.95 7.2 6.4 0.48 8.2 2.6 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 CEP08526.1 - 1.7 7.5 12.6 3.3 6.5 8.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HSP70 PF00012.15 CEP08526.1 - 2.8 5.7 10.8 11 3.8 0.0 2.4 2 0 0 2 2 2 0 Hsp70 protein DNA_pol_A_exo1 PF01612.15 CEP08527.1 - 8.5e-08 31.8 0.1 1.5e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Na_Ca_ex PF01699.19 CEP08528.1 - 4.3e-17 62.0 17.5 2.6e-12 46.5 6.6 3.0 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CEP08528.1 - 4.6e-11 42.9 7.2 4.6e-11 42.9 5.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF307) PBP1_TM PF14812.1 CEP08528.1 - 2.4 8.5 9.3 34 4.8 0.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APG5 PF04106.7 CEP08529.1 - 0.028 13.8 0.1 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 Herpes_TAF50 PF03326.8 CEP08531.1 - 0.18 10.7 10.0 0.21 10.4 6.9 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF1010 PF06231.6 CEP08532.1 - 1.2 9.1 4.9 0.68 9.9 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1010) WD40 PF00400.27 CEP08536.1 - 1.1e-58 193.1 19.5 7.3e-09 35.1 0.0 11.7 12 0 0 12 12 12 9 WD domain, G-beta repeat eIF2A PF08662.6 CEP08536.1 - 4.6e-12 46.0 2.6 0.0049 16.6 0.1 4.3 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 CEP08536.1 - 2.1e-06 27.4 0.2 2.4 7.9 0.0 4.3 3 1 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 CEP08536.1 - 2e-05 24.7 4.5 0.39 11.0 0.1 5.0 6 0 0 6 6 6 2 PQQ-like domain IKI3 PF04762.7 CEP08536.1 - 0.00017 19.6 0.0 0.094 10.5 0.0 2.8 2 1 0 2 2 2 2 IKI3 family Coatomer_WDAD PF04053.9 CEP08536.1 - 0.0037 16.1 2.2 0.047 12.4 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region CPSF_A PF03178.10 CEP08536.1 - 0.0098 15.0 0.1 0.059 12.4 0.0 2.2 2 1 0 2 2 2 1 CPSF A subunit region Toxin_57 PF15535.1 CEP08536.1 - 0.1 12.6 0.1 3.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Putative toxin 57 DUF4221 PF13970.1 CEP08536.1 - 0.18 11.0 1.9 55 2.9 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4221) VCBS PF13517.1 CEP08536.1 - 1 9.7 5.7 3.1 8.2 0.3 4.2 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_S19e PF01090.14 CEP08537.1 - 4.6e-56 188.1 0.1 5.2e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e E1-E2_ATPase PF00122.15 CEP08538.1 - 2e-27 95.7 0.4 1e-26 93.4 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CEP08538.1 - 8.7e-16 58.6 0.0 2e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP08538.1 - 1.2e-11 45.4 0.0 6.1e-11 43.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP08538.1 - 0.00022 20.6 0.0 0.0006 19.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF4156 PF13698.1 CEP08538.1 - 0.01 15.6 1.5 6 6.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4156) SCA7 PF08313.7 CEP08539.1 - 8.3e-30 102.2 2.5 2.5e-29 100.7 1.7 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Tachystatin_A PF11406.3 CEP08539.1 - 0.051 13.4 0.4 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A Phostensin_N PF13916.1 CEP08539.1 - 0.52 10.3 3.5 2 8.4 1.7 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal GATA PF00320.22 CEP08540.1 - 4.9e-15 54.5 4.0 4.9e-15 54.5 2.8 1.8 2 0 0 2 2 2 1 GATA zinc finger DELLA PF12041.3 CEP08540.1 - 0.068 12.8 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DSPc PF00782.15 CEP08542.1 - 1.6e-33 115.1 0.2 3.5e-32 110.7 0.2 2.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP08542.1 - 1.2e-05 24.7 0.2 2.9e-05 23.5 0.2 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CEP08542.1 - 0.0057 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Tachylectin PF14517.1 CEP08543.1 - 0.061 12.6 0.5 0.19 11.0 0.4 1.8 1 1 0 1 1 1 0 Tachylectin MyTH4 PF00784.12 CEP08544.1 - 3e-27 94.8 1.0 7.6e-27 93.5 0.1 2.2 2 1 0 2 2 2 1 MyTH4 domain RhoGAP PF00620.22 CEP08544.1 - 4.9e-27 94.4 0.0 1.2e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos_2 PF14529.1 CEP08545.1 - 7.6e-12 44.8 0.3 2e-11 43.5 0.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP08545.1 - 6.5e-07 29.5 2.7 1.9e-06 28.0 0.5 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PMBR PF09373.5 CEP08545.1 - 0.14 12.1 0.8 0.96 9.5 0.1 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat MDMPI_N PF11716.3 CEP08547.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.7 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Defensin_1 PF00323.14 CEP08548.1 - 0.12 12.6 3.4 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Mammalian defensin PIG-U PF06728.8 CEP08549.1 - 1.4e-87 294.1 33.6 3.1e-48 164.5 9.4 2.1 1 1 1 2 2 2 2 GPI transamidase subunit PIG-U DUF3353 PF11833.3 CEP08549.1 - 0.88 8.9 4.4 1.7 8.0 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Dynamin_N PF00350.18 CEP08550.1 - 1.1e-16 61.0 2.6 4e-16 59.2 0.0 3.1 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 CEP08550.1 - 1.1e-09 38.1 0.1 9.1e-09 35.2 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP08550.1 - 6.5e-08 32.2 0.9 1.4e-06 27.8 0.6 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CEP08550.1 - 0.00099 19.5 0.2 0.081 13.4 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein DUF258 PF03193.11 CEP08550.1 - 0.0042 16.2 0.0 0.011 14.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEP08550.1 - 0.0065 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RHINO PF15319.1 CEP08551.1 - 0.028 14.2 0.5 0.041 13.6 0.4 1.3 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein RVT_1 PF00078.22 CEP08553.1 - 4.6e-18 65.3 0.0 5.8e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PGDYG PF14083.1 CEP08554.1 - 0.033 14.5 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 PGDYG protein DNA_pol_A_exo1 PF01612.15 CEP08555.1 - 4.3e-08 32.8 0.0 8.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease DUF2905 PF11146.3 CEP08556.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) zf-H2C2 PF09337.5 CEP08557.1 - 1.3e-05 24.5 1.1 2.8e-05 23.4 0.8 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve PF00665.21 CEP08558.1 - 1.7e-17 63.6 0.0 4.2e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP08558.1 - 3.6e-08 32.9 0.3 8.3e-08 31.7 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP08558.1 - 0.00038 19.8 1.6 0.00038 19.8 1.1 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger APG6 PF04111.7 CEP08559.1 - 0.11 11.4 2.3 0.16 10.9 1.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Vip3A_N PF12495.3 CEP08560.1 - 0.088 12.4 0.1 0.097 12.3 0.1 1.0 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal BRE1 PF08647.6 CEP08560.1 - 0.11 12.5 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Asp_protease_2 PF13650.1 CEP08563.1 - 6.9e-05 23.2 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP08563.1 - 0.00011 22.0 0.0 0.00067 19.5 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP08563.1 - 0.0094 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 CEP08563.1 - 0.15 11.6 0.3 0.59 9.7 0.2 1.9 1 1 0 1 1 1 0 Aspartyl protease VGLL4 PF15245.1 CEP08565.1 - 1.7 8.4 6.3 0.36 10.6 1.5 1.7 1 1 1 2 2 2 0 Transcription cofactor vestigial-like protein 4 TEX19 PF15553.1 CEP08566.1 - 0.14 12.0 0.4 0.16 11.8 0.3 1.0 1 0 0 1 1 1 0 Testis-expressed protein 19 Spt5_N PF11942.3 CEP08566.1 - 0.3 11.7 6.2 0.32 11.6 4.3 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2457 PF10446.4 CEP08566.1 - 0.44 9.2 7.4 0.47 9.1 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Helitron_like_N PF14214.1 CEP08567.1 - 6.4e-22 78.1 0.6 1.4e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus FAR1 PF03101.10 CEP08568.1 - 4.5e-08 33.5 2.1 6.9e-08 32.9 1.5 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain BrkDBD PF09607.5 CEP08568.1 - 0.065 12.8 0.1 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain zf-BED PF02892.10 CEP08569.1 - 0.0048 16.6 0.8 0.012 15.3 0.6 1.6 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.21 CEP08569.1 - 0.74 10.2 9.5 0.22 11.9 2.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type HK97-gp10_like PF04883.7 CEP08569.1 - 2.5 9.1 7.9 0.11 13.4 1.1 2.0 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component zf-C2H2_4 PF13894.1 CEP08569.1 - 2.7 8.5 6.0 0.5 10.8 1.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_4C PF11975.3 CEP08569.1 - 3.1 7.5 7.8 0.5 10.1 2.5 1.7 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain DUF4499 PF14934.1 CEP08570.1 - 4.2e-08 33.0 0.2 8.2e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.4 CEP08570.1 - 0.0037 17.4 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Ribosomal_L38e PF01781.13 CEP08571.1 - 4.2e-33 112.9 1.9 4.5e-33 112.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_90kDa PF04494.10 CEP08571.1 - 0.062 13.3 0.2 0.07 13.1 0.1 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit DUF2654 PF10849.3 CEP08571.1 - 0.089 12.5 0.3 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) RNA_pol_Rbc25 PF08292.7 CEP08572.1 - 5.2e-38 129.9 0.0 7.1e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CEP08572.1 - 3.1e-18 65.6 0.2 5.4e-18 64.8 0.2 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CEP08572.1 - 0.0031 17.5 0.0 0.0087 16.1 0.0 1.9 1 1 0 1 1 1 1 S1 RNA binding domain DUF273 PF03314.9 CEP08572.1 - 0.021 14.1 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Pkinase PF00069.20 CEP08573.1 - 1.1e-38 132.8 0.0 2e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08573.1 - 1.3e-16 60.4 0.0 2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA PF00627.26 CEP08573.1 - 1.9e-05 24.3 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain APH PF01636.18 CEP08573.1 - 0.0037 17.0 0.0 0.096 12.4 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP08573.1 - 0.07 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like SET PF00856.23 CEP08574.1 - 6.8e-09 36.2 0.1 3.7e-07 30.6 0.1 2.2 1 1 0 1 1 1 1 SET domain DEAD PF00270.24 CEP08575.1 - 2.7e-44 150.6 0.1 6.5e-44 149.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CEP08575.1 - 5.3e-25 86.7 0.5 1.4e-24 85.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CEP08575.1 - 3.1e-21 75.0 0.0 9e-21 73.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 CEP08576.1 - 4.5e-67 221.8 1.1 1.5e-24 85.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PMI_typeI PF01238.16 CEP08577.1 - 7e-73 245.7 0.0 8.4e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 CEP08577.1 - 0.0073 15.7 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain PMI_typeI PF01238.16 CEP08578.1 - 1.3e-42 146.1 0.0 1.4e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Phage_connector PF05352.7 CEP08578.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Phage Connector (GP10) GATA PF00320.22 CEP08579.1 - 1.5e-15 56.2 7.0 1.5e-15 56.2 4.8 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_3 PF08447.6 CEP08579.1 - 4.9e-14 52.1 0.0 8.4e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 CEP08579.1 - 1.3e-07 31.9 0.1 4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 CEP08579.1 - 2.6e-07 30.4 0.0 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 CEP08579.1 - 4e-06 26.7 0.4 1.1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 CEP08579.1 - 3.8e-05 23.6 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 CEP08579.1 - 0.065 13.1 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 PAS domain Peptidase_S10 PF00450.17 CEP08580.1 - 5.4e-126 421.1 0.7 6.8e-126 420.7 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CEP08580.1 - 0.036 13.9 0.0 2.2 8.0 0.0 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase family Sec7 PF01369.15 CEP08581.1 - 5.3e-58 195.8 0.0 1e-57 194.8 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CEP08581.1 - 1.3e-17 63.7 2.4 8.4e-10 38.3 0.1 3.3 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2981 PF11200.3 CEP08581.1 - 0.11 11.5 1.6 0.24 10.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2981) EF-hand_4 PF12763.2 CEP08584.1 - 1.5e-31 108.2 0.0 1e-12 47.7 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand Tmemb_14 PF03647.8 CEP08584.1 - 4.5e-18 65.4 1.7 4.5e-18 65.4 1.2 1.9 2 0 0 2 2 2 1 Transmembrane proteins 14C EF-hand_7 PF13499.1 CEP08584.1 - 1.4e-15 57.1 0.6 1.3e-05 25.1 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CEP08584.1 - 2.3e-12 45.2 2.0 0.034 13.4 0.0 5.3 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CEP08584.1 - 5.2e-09 35.2 0.4 0.33 10.9 0.0 5.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CEP08584.1 - 0.00018 21.0 0.1 6.7 6.4 0.0 4.4 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 CEP08584.1 - 0.02 14.2 0.0 0.19 11.1 0.0 2.4 2 0 0 2 2 2 0 EF hand Erp_C PF06780.6 CEP08584.1 - 0.079 12.8 5.3 0.15 11.9 3.7 1.4 1 0 0 1 1 1 0 Erp protein C-terminus DUF4203 PF13886.1 CEP08584.1 - 0.19 11.1 0.3 0.31 10.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) EF-hand_10 PF14788.1 CEP08584.1 - 0.28 10.8 2.9 23 4.7 0.2 3.5 4 0 0 4 4 4 0 EF hand HNH_4 PF13395.1 CEP08585.1 - 0.026 14.1 0.1 0.061 12.9 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease DZR PF12773.2 CEP08585.1 - 0.082 12.7 0.3 0.27 11.0 0.2 1.9 1 0 0 1 1 1 0 Double zinc ribbon HTH_28 PF13518.1 CEP08587.1 - 0.001 19.0 0.1 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TerB-C PF15615.1 CEP08587.1 - 0.051 13.8 0.2 0.064 13.5 0.1 1.1 1 0 0 1 1 1 0 TerB-C domain HTH_Tnp_1 PF01527.15 CEP08587.1 - 0.36 10.8 1.8 0.38 10.7 0.2 1.8 2 0 0 2 2 2 0 Transposase Sugar_tr PF00083.19 CEP08588.1 - 7.7e-54 182.9 24.5 9.5e-54 182.6 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP08588.1 - 2.2e-22 79.2 34.7 3.3e-14 52.3 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SH3_9 PF14604.1 CEP08591.1 - 3.4e-10 39.3 0.0 5.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP08591.1 - 7.2e-07 28.5 0.0 1.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain VSP PF03302.8 CEP08591.1 - 1.2e-06 27.4 5.4 2e-06 26.7 3.7 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SH3_2 PF07653.12 CEP08591.1 - 0.00021 20.7 0.0 0.00039 19.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Shisa PF13908.1 CEP08591.1 - 0.015 15.4 1.2 0.015 15.4 0.9 3.1 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator IncA PF04156.9 CEP08591.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 IncA protein DUF4342 PF14242.1 CEP08591.1 - 0.087 12.6 1.1 12 5.7 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Rifin_STEVOR PF02009.11 CEP08591.1 - 0.47 10.0 13.8 3.4 7.2 9.5 2.0 1 1 0 1 1 1 0 Rifin/stevor family zf-C2H2_4 PF13894.1 CEP08592.1 - 1.5e-05 24.9 9.9 0.024 14.9 0.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP08592.1 - 0.00026 21.1 16.2 0.012 15.9 0.6 3.8 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP08592.1 - 0.037 14.3 12.3 0.24 11.7 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double domain CBF PF03914.12 CEP08593.1 - 1.1e-45 154.9 0.1 1.1e-45 154.9 0.1 3.5 4 0 0 4 4 4 1 CBF/Mak21 family Cnd1_N PF12922.2 CEP08593.1 - 0.0065 16.1 1.7 0.0065 16.1 1.2 3.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 CEP08593.1 - 0.13 12.1 10.5 0.039 13.8 2.7 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 SBF PF01758.11 CEP08593.1 - 0.31 10.4 0.0 0.51 9.7 0.0 1.2 1 0 0 1 1 1 0 Sodium Bile acid symporter family HEAT PF02985.17 CEP08593.1 - 0.41 10.8 1.9 2.5 8.4 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat Ion_trans PF00520.26 CEP08594.1 - 6.8e-115 381.2 95.6 3.5e-40 137.3 12.1 5.1 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 CEP08594.1 - 1.7 7.0 85.2 0.0057 15.1 4.5 7.4 5 2 2 7 7 7 0 Polycystin cation channel CPSase_L_D2 PF02786.12 CEP08596.1 - 1.2e-111 371.0 0.1 4e-83 277.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CEP08596.1 - 1.5e-46 157.0 0.0 3.4e-46 155.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CEP08596.1 - 8.3e-45 152.6 0.0 2.6e-44 150.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 CEP08596.1 - 4.9e-44 149.4 0.0 1e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 CEP08596.1 - 8.5e-42 141.7 0.0 2.3e-21 75.9 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CEP08596.1 - 6.8e-41 138.8 0.0 1.9e-40 137.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 CEP08596.1 - 2.8e-38 131.2 0.2 1.1e-37 129.3 0.1 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CEP08596.1 - 5.3e-34 117.5 0.1 2.2e-22 79.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP08596.1 - 6.2e-22 77.7 0.0 2.6e-11 42.8 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CEP08596.1 - 2.6e-19 68.9 0.0 1.6e-18 66.4 0.0 2.5 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 CEP08596.1 - 1.8e-13 50.3 0.5 2.9e-06 26.8 0.0 3.0 2 1 1 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CEP08596.1 - 2.7e-13 49.6 0.1 7.5e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 CEP08596.1 - 3.2e-05 23.4 0.1 0.0014 18.1 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CEP08596.1 - 0.00017 21.4 0.3 0.17 11.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain DcpS_C PF11969.3 CEP08597.1 - 2.6e-25 88.8 0.0 4.7e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 CEP08597.1 - 3e-20 72.6 0.1 5e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal IBR PF01485.16 CEP08598.1 - 2.5e-08 33.6 10.6 2.5e-08 33.6 7.3 5.2 2 1 0 2 2 2 1 IBR domain Med3 PF11593.3 CEP08598.1 - 0.64 9.2 2.7 1.1 8.3 1.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 CEP08599.1 - 3e-74 249.4 0.0 6e-74 248.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08599.1 - 1.3e-38 132.5 0.0 2e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP08599.1 - 4e-05 23.4 0.0 0.0071 16.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Marek_SORF3 PF07153.6 CEP08599.1 - 0.011 14.4 1.5 0.69 8.5 0.0 2.5 2 0 0 2 2 2 0 Marek's disease-like virus SORF3 protein Choline_kinase PF01633.15 CEP08599.1 - 0.026 14.1 0.9 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2666 PF10869.3 CEP08600.1 - 0.085 12.8 5.4 0.17 11.9 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) V-SNARE PF05008.10 CEP08600.1 - 0.23 11.6 4.4 0.5 10.5 2.1 2.3 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus ADP_ribosyl_GH PF03747.9 CEP08601.1 - 6.9e-45 154.0 0.0 1.6e-44 152.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase Fork_head PF00250.13 CEP08602.1 - 1.1e-16 60.6 0.3 7.2e-15 54.8 0.2 2.3 1 1 0 1 1 1 1 Fork head domain YABBY PF04690.8 CEP08602.1 - 0.017 15.3 0.3 0.025 14.8 0.2 1.3 1 0 0 1 1 1 0 YABBY protein Pkinase PF00069.20 CEP08603.1 - 4.8e-70 235.6 0.0 6e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08603.1 - 3.4e-34 118.0 0.0 4.6e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CEP08603.1 - 3e-05 23.4 0.0 5.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CEP08603.1 - 0.00012 21.1 0.0 0.07 12.0 0.0 2.9 2 1 0 3 3 3 2 Kinase-like p450 PF00067.17 CEP08604.1 - 1.9e-64 217.8 0.0 8.4e-64 215.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Prefoldin_2 PF01920.15 CEP08604.1 - 7.7e-23 80.2 12.7 1.8e-22 79.1 8.8 1.7 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.4 CEP08604.1 - 0.025 14.7 1.5 0.025 14.7 1.0 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_23 PF13476.1 CEP08604.1 - 0.072 13.4 9.7 0.59 10.4 5.5 2.3 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.7 CEP08604.1 - 0.081 12.6 2.6 0.63 9.7 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF948 PF06103.6 CEP08604.1 - 0.13 12.1 1.8 0.35 10.7 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 CEP08604.1 - 0.43 10.8 2.9 14 5.9 0.3 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.6 CEP08604.1 - 2.4 8.3 7.5 17 5.6 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DivIC PF04977.10 CEP08604.1 - 2.6 7.5 11.2 0.78 9.2 2.1 2.7 2 0 0 2 2 2 0 Septum formation initiator Nfu_N PF08712.6 CEP08605.1 - 2.7e-31 107.0 0.0 6.8e-31 105.7 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CEP08605.1 - 2e-23 81.9 0.1 3.1e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 CEP08605.1 - 0.068 13.0 0.3 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Pex24p PF06398.6 CEP08606.1 - 2e-21 76.1 11.4 3e-21 75.6 7.9 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin MCM PF00493.18 CEP08607.1 - 2e-137 457.4 1.0 3.3e-137 456.7 0.7 1.4 1 0 0 1 1 1 1 MCM2/3/5 family tRNA-synt_1d PF00750.14 CEP08607.1 - 5.1e-73 245.9 3.7 7.8e-73 245.3 2.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CEP08607.1 - 5.3e-25 87.6 0.0 1.8e-24 86.0 0.0 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain MCM_N PF14551.1 CEP08607.1 - 1.2e-23 83.8 0.3 4.7e-23 81.9 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CEP08607.1 - 3.7e-05 22.9 0.0 0.001 18.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CEP08607.1 - 0.00013 21.7 0.0 0.00041 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CEP08607.1 - 0.0011 18.6 0.0 0.0062 16.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2108 PF09881.4 CEP08609.1 - 0.037 13.8 1.3 0.094 12.5 0.9 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) DUF2721 PF11026.3 CEP08609.1 - 0.74 9.4 8.8 0.46 10.1 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) DUF485 PF04341.7 CEP08609.1 - 1.7 8.3 22.8 0.52 10.0 0.5 4.2 4 0 0 4 4 4 0 Protein of unknown function, DUF485 HAD_2 PF13419.1 CEP08610.1 - 4.8e-20 72.4 0.0 5.8e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP08610.1 - 3.5e-07 30.8 0.0 7.6e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP08610.1 - 0.0029 17.3 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like STAT1_TAZ2bind PF12162.3 CEP08610.1 - 0.16 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain PIF1 PF05970.9 CEP08612.1 - 4.4e-57 193.6 3.3 7.3e-32 110.7 0.0 2.5 2 1 1 3 3 3 2 PIF1-like helicase IncFII_repA PF02387.10 CEP08613.1 - 0.069 12.2 0.2 0.097 11.8 0.1 1.1 1 0 0 1 1 1 0 IncFII RepA protein family RVP_2 PF08284.6 CEP08614.1 - 3.2e-06 27.1 0.3 7.1e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.1 CEP08614.1 - 0.0012 18.4 0.1 0.0031 17.1 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 CEP08614.1 - 0.0033 17.2 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4187 PF13821.1 CEP08614.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-CCHC PF00098.18 CEP08614.1 - 0.029 14.2 1.6 0.052 13.4 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-FCS PF06467.9 CEP08615.1 - 0.042 13.5 1.6 0.37 10.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif KilA-N PF04383.8 CEP08617.1 - 0.002 17.7 0.0 0.011 15.3 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Aldo_ket_red PF00248.16 CEP08618.1 - 1.4e-60 204.5 0.0 1.6e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_46 PF01374.13 CEP08619.1 - 5.5e-29 101.2 0.2 1.2e-28 100.1 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 46 MutS_V PF00488.16 CEP08620.1 - 2.8e-96 321.4 0.1 4.3e-96 320.8 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CEP08620.1 - 1.1e-38 133.0 1.3 2.9e-38 131.7 0.9 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 CEP08620.1 - 3.9e-17 62.5 0.7 2.2e-16 60.1 0.1 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 CEP08620.1 - 1.5e-13 50.7 2.6 1.5e-13 50.7 1.8 2.7 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 CEP08620.1 - 1.3e-08 34.8 0.1 3.2e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 MutS domain I Mst1_SARAH PF11629.3 CEP08620.1 - 0.13 12.1 1.7 0.31 10.8 0.3 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Tup_N PF08581.5 CEP08620.1 - 0.18 12.0 11.0 0.57 10.4 1.1 4.1 3 0 0 3 3 3 0 Tup N-terminal Wbp11 PF09429.5 CEP08620.1 - 4.1 7.4 6.1 0.57 10.1 0.3 2.5 2 0 0 2 2 2 0 WW domain binding protein 11 PTS-HPr PF00381.14 CEP08621.1 - 1.3e-17 63.3 0.0 1.5e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site Aa_trans PF01490.13 CEP08622.1 - 2.7e-77 259.9 36.0 3.2e-77 259.7 24.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TAP35_44 PF07265.6 CEP08622.1 - 0.15 11.8 0.9 3.6 7.3 0.0 3.3 3 0 0 3 3 3 0 Tapetum specific protein TAP35/TAP44 ICL PF00463.16 CEP08623.1 - 1.5e-254 845.0 2.4 1.7e-254 844.8 1.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CEP08623.1 - 9.8e-10 38.0 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Humanin PF15040.1 CEP08624.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Humanin family M16C_assoc PF08367.6 CEP08625.1 - 2.8e-75 252.3 0.8 4.4e-75 251.7 0.1 1.7 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 CEP08625.1 - 1.8e-33 115.7 0.1 7.7e-21 74.5 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CEP08625.1 - 2e-08 34.1 0.9 1.4e-06 28.1 0.0 3.5 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) DUF99 PF01949.11 CEP08625.1 - 0.063 12.3 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF99 NETI PF14044.1 CEP08625.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 NETI protein DUF2312 PF10073.4 CEP08625.1 - 0.099 12.0 4.2 2.9 7.3 0.1 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) Xan_ur_permease PF00860.15 CEP08626.1 - 2.6e-56 190.7 34.6 4.6e-55 186.7 24.0 2.1 1 1 0 1 1 1 1 Permease family dCMP_cyt_deam_1 PF00383.17 CEP08627.1 - 4.3e-12 45.5 0.0 1.1e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CEP08627.1 - 0.00076 19.3 0.7 0.0028 17.4 0.5 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase DUF1065 PF06358.6 CEP08627.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) DIOX_N PF14226.1 CEP08628.1 - 4.3e-21 75.6 0.0 8.7e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CEP08628.1 - 1.2e-11 44.7 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA PF00004.24 CEP08629.1 - 1.4e-51 174.1 0.0 2.1e-41 141.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEP08629.1 - 3.8e-11 43.3 0.3 0.00024 21.1 0.1 3.7 3 1 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 CEP08629.1 - 7.1e-09 35.9 0.7 0.0067 16.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CEP08629.1 - 1.2e-06 28.8 0.1 0.014 15.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_14 PF13173.1 CEP08629.1 - 1.7e-06 27.9 0.0 0.002 18.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 CEP08629.1 - 3.8e-06 26.0 0.0 0.006 15.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CEP08629.1 - 3.9e-06 26.7 0.0 0.00087 19.0 0.0 2.8 2 1 0 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 CEP08629.1 - 4.9e-06 26.3 0.4 0.097 12.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CEP08629.1 - 8.2e-06 26.6 0.1 0.19 12.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEP08629.1 - 1.5e-05 24.2 0.4 0.047 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 CEP08629.1 - 4.6e-05 23.1 4.0 0.061 12.9 0.0 3.8 4 1 0 4 4 4 2 NACHT domain AAA_2 PF07724.9 CEP08629.1 - 8.2e-05 22.5 0.0 0.033 14.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CEP08629.1 - 9.1e-05 22.5 0.1 0.018 15.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 CEP08629.1 - 0.00017 21.5 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 CEP08629.1 - 0.00024 19.9 0.1 0.0057 15.3 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CEP08629.1 - 0.00024 20.2 0.0 0.036 13.1 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 CEP08629.1 - 0.00025 20.5 0.0 0.17 11.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 CEP08629.1 - 0.00032 20.2 0.0 0.51 9.8 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CEP08629.1 - 0.00039 19.8 0.1 0.088 12.2 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 CEP08629.1 - 0.00043 20.6 0.0 0.9 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CEP08629.1 - 0.00044 19.0 0.1 0.044 12.5 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus PduV-EutP PF10662.4 CEP08629.1 - 0.00053 19.5 0.2 0.083 12.3 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.16 CEP08629.1 - 0.00058 19.0 0.1 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 CEP08629.1 - 0.00079 19.8 0.0 1.3 9.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 CEP08629.1 - 0.00089 18.9 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_19 PF13245.1 CEP08629.1 - 0.001 18.7 0.2 1.5 8.6 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 CEP08629.1 - 0.0018 18.7 0.1 0.11 12.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein KaiC PF06745.8 CEP08629.1 - 0.0028 16.8 0.1 0.49 9.4 0.0 2.4 2 0 0 2 2 2 1 KaiC SRPRB PF09439.5 CEP08629.1 - 0.0043 16.2 0.1 0.18 10.9 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit UPF0079 PF02367.12 CEP08629.1 - 0.0079 15.8 0.3 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CEP08629.1 - 0.01 15.8 0.1 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 CEP08629.1 - 0.016 15.1 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CEP08629.1 - 0.017 14.2 0.0 0.83 8.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 CEP08629.1 - 0.018 14.5 0.0 7.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 CEP08629.1 - 0.018 14.4 0.5 1.1 8.6 0.2 3.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CEP08629.1 - 0.024 14.2 2.0 1.3 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 CEP08629.1 - 0.025 14.3 0.5 6.6 6.4 0.1 2.6 2 0 0 2 2 2 0 NTPase AFG1_ATPase PF03969.11 CEP08629.1 - 0.052 12.3 0.0 1.1 8.0 0.0 2.4 3 0 0 3 3 3 0 AFG1-like ATPase NB-ARC PF00931.17 CEP08629.1 - 0.056 12.2 1.1 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Adeno_IVa2 PF02456.10 CEP08629.1 - 0.057 12.0 0.1 0.2 10.2 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein T2SE PF00437.15 CEP08629.1 - 0.072 11.9 0.1 9.3 5.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Septin PF00735.13 CEP08629.1 - 0.082 11.9 0.3 2.1 7.2 0.0 2.6 2 1 1 3 3 3 0 Septin CPT PF07931.7 CEP08629.1 - 0.1 12.2 0.4 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ATP-synt_ab PF00006.20 CEP08629.1 - 0.13 11.7 0.3 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.14 CEP08629.1 - 0.19 10.9 0.4 23 4.1 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CEP08629.1 - 0.2 11.0 1.7 7.7 5.8 0.0 2.8 2 1 1 3 3 3 0 AAA-like domain RhoGAP PF00620.22 CEP08630.1 - 2.7e-26 92.0 0.5 1.9e-15 56.7 0.0 2.9 2 1 1 3 3 3 2 RhoGAP domain FCH PF00611.18 CEP08630.1 - 2.6e-15 56.3 0.3 1.2e-14 54.2 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BACK PF07707.10 CEP08630.1 - 0.059 13.2 0.1 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch TPR_MLP1_2 PF07926.7 CEP08630.1 - 9 6.0 14.1 0.98 9.1 0.5 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Mito_carr PF00153.22 CEP08632.1 - 1e-69 230.3 4.4 3.2e-24 84.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CEP08632.1 - 2.8e-05 24.1 4.8 0.018 15.0 0.0 3.5 3 1 0 3 3 3 3 Tim17/Tim22/Tim23/Pmp24 family DUF2043 PF09740.4 CEP08633.1 - 8.1e-26 90.3 0.0 2.4e-25 88.8 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) Med28 PF11594.3 CEP08633.1 - 2.8 8.2 10.1 4.4 7.5 1.8 3.2 3 0 0 3 3 3 0 Mediator complex subunit 28 Aldo_ket_red PF00248.16 CEP08634.1 - 3e-59 200.1 0.0 4e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SAP18 PF06487.7 CEP08634.1 - 7.3e-39 132.2 0.0 1.3e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Gcw_chp PF09694.5 CEP08634.1 - 0.17 11.6 0.3 0.32 10.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) Recep_L_domain PF01030.19 CEP08635.1 - 4e-11 42.8 10.5 8.9e-05 22.4 0.9 4.6 1 1 2 4 4 4 4 Receptor L domain LRR_5 PF13306.1 CEP08635.1 - 0.0014 18.3 0.4 0.34 10.6 0.0 3.3 1 1 2 3 3 3 2 Leucine rich repeats (6 copies) Ribosomal_L10 PF00466.15 CEP08636.1 - 9.4e-11 41.5 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_C97 PF05903.9 CEP08637.1 - 4.3e-19 68.7 0.3 1.4e-08 34.6 0.0 2.2 1 1 1 2 2 2 2 PPPDE putative peptidase domain GRAB PF10375.4 CEP08638.1 - 4.3e-06 26.1 0.1 4.3e-06 26.1 0.1 2.5 2 0 0 2 2 2 1 GRIP-related Arf-binding domain ADIP PF11559.3 CEP08638.1 - 0.00029 20.7 13.5 0.00029 20.7 9.4 6.8 2 2 4 6 6 6 3 Afadin- and alpha -actinin-Binding Filament PF00038.16 CEP08638.1 - 0.002 17.6 97.0 0.0086 15.5 20.8 4.9 1 1 2 4 4 4 3 Intermediate filament protein Seryl_tRNA_N PF02403.17 CEP08638.1 - 0.0027 17.7 18.6 0.0027 17.7 12.9 7.8 3 1 5 8 8 8 3 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.7 CEP08638.1 - 0.63 9.8 55.1 0.14 12.0 2.6 6.4 2 2 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CEP08638.1 - 0.69 9.0 35.0 2.6 7.1 2.8 4.3 2 2 2 4 4 4 0 Reovirus sigma C capsid protein PLAC9 PF15205.1 CEP08638.1 - 1.2 9.4 8.7 6.6 7.0 0.1 4.4 2 2 1 3 3 3 0 Placenta-specific protein 9 DUF3584 PF12128.3 CEP08638.1 - 1.8 5.7 101.6 0.036 11.4 16.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 CEP08638.1 - 8.3 6.5 82.0 0.22 11.6 9.4 6.5 1 1 4 6 6 6 0 Fibrinogen alpha/beta chain family QueF PF14489.1 CEP08639.1 - 0.031 14.2 0.0 0.81 9.6 0.0 2.2 2 0 0 2 2 2 0 QueF-like protein DUF4286 PF14114.1 CEP08640.1 - 0.018 15.3 0.2 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Ins145_P3_rec PF08709.6 CEP08642.1 - 0.014 14.4 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor zf-C2HC_2 PF13913.1 CEP08642.1 - 0.088 12.4 0.8 0.088 12.4 0.5 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.2 CEP08642.1 - 0.12 12.2 9.0 0.38 10.6 0.8 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.8 CEP08642.1 - 0.35 10.5 14.4 8.6 6.1 2.2 3.6 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 CEP08642.1 - 0.47 10.6 10.8 4.1 7.6 0.4 2.9 2 1 0 2 2 2 0 CHY zinc finger zinc_ribbon_5 PF13719.1 CEP08642.1 - 1 8.9 10.6 2.2 7.9 0.3 4.0 4 0 0 4 4 4 0 zinc-ribbon domain PHD PF00628.24 CEP08642.1 - 1.2 8.9 11.3 4.5 7.0 1.0 2.8 2 2 0 2 2 2 0 PHD-finger DnaJ_CXXCXGXG PF00684.14 CEP08642.1 - 1.2 9.2 6.9 5.8 7.0 0.6 3.2 3 0 0 3 3 3 0 DnaJ central domain zinc_ribbon_4 PF13717.1 CEP08642.1 - 3 7.5 12.3 3.3 7.4 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.16 CEP08642.1 - 5.7 6.8 10.7 2.2 8.1 0.6 2.7 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 CEP08642.1 - 7 6.7 15.2 12 5.9 0.3 3.8 2 2 1 3 3 3 0 TFIIH C1-like domain CpXC PF14353.1 CEP08642.1 - 7.9 6.4 9.1 28 4.6 3.9 2.6 2 1 0 2 2 2 0 CpXC protein Na_Ca_ex PF01699.19 CEP08644.1 - 3.5e-07 29.8 1.9 4.5e-07 29.5 1.3 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein NMN_transporter PF04973.7 CEP08644.1 - 0.073 12.5 4.4 0.06 12.7 0.8 1.9 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter UcrQ PF02939.11 CEP08644.1 - 0.11 12.2 2.4 0.54 10.1 0.1 2.2 2 0 0 2 2 2 0 UcrQ family SPC25 PF06703.6 CEP08644.1 - 0.35 10.4 2.1 0.33 10.5 1.0 1.3 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) YoqO PF14037.1 CEP08644.1 - 0.45 10.6 3.3 0.37 10.9 1.1 1.6 1 1 1 2 2 2 0 YoqO-like protein DUF997 PF06196.7 CEP08644.1 - 1.3 8.6 6.5 0.33 10.5 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF997) Chitin_synth_2 PF03142.10 CEP08645.1 - 1.7e-239 795.6 0.9 2.7e-239 794.9 0.6 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEP08645.1 - 4.6e-98 329.0 0.4 1e-97 327.8 0.3 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 CEP08645.1 - 7.8e-19 67.2 3.1 2.5e-17 62.3 2.0 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 CEP08645.1 - 2e-17 63.5 1.3 2e-17 63.5 0.9 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP08645.1 - 3.2e-17 63.0 0.0 5e-14 52.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CEP08645.1 - 5.4e-17 61.3 0.0 2e-09 37.1 0.0 3.1 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CEP08645.1 - 1.1e-06 28.4 0.0 0.0008 19.1 0.0 2.9 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP08645.1 - 0.00011 21.4 0.0 0.0028 16.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 FtsK_SpoIIIE PF01580.13 CEP08645.1 - 0.011 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 CEP08645.1 - 0.015 14.1 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 CEP08645.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 CEP08645.1 - 0.041 13.4 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CEP08645.1 - 0.079 13.1 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEP08645.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MULE PF10551.4 CEP08646.1 - 0.0023 18.0 0.2 0.0046 17.0 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain WRKY PF03106.10 CEP08646.1 - 0.014 15.1 0.1 0.041 13.7 0.1 1.8 1 0 0 1 1 1 0 WRKY DNA -binding domain DUF4411 PF14367.1 CEP08646.1 - 0.027 14.1 0.6 0.078 12.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) FAR1 PF03101.10 CEP08646.1 - 0.081 13.4 0.5 0.26 11.8 0.3 1.9 1 1 0 1 1 1 0 FAR1 DNA-binding domain MULE PF10551.4 CEP08648.1 - 4.1e-21 74.9 0.1 1.3e-20 73.2 0.1 2.0 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 CEP08648.1 - 2.2e-08 34.4 2.2 2.2e-08 34.4 1.5 3.6 3 0 0 3 3 3 1 FAR1 DNA-binding domain OTU PF02338.14 CEP08648.1 - 0.00042 20.8 0.2 0.0043 17.6 0.0 2.8 3 0 0 3 3 3 1 OTU-like cysteine protease Transposase_mut PF00872.13 CEP08648.1 - 0.0014 17.2 0.0 0.0014 17.2 0.0 1.9 2 0 0 2 2 2 1 Transposase, Mutator family Colicin-DNase PF12639.2 CEP08648.1 - 0.78 10.0 9.0 4.2 7.6 1.6 3.3 3 0 0 3 3 3 0 DNase/tRNase domain of colicin-like bacteriocin Sec23_trunk PF04811.10 CEP08649.1 - 3.7e-58 196.7 0.0 1.2e-56 191.7 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CEP08649.1 - 5.9e-19 67.4 1.2 8.5e-19 66.9 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CEP08649.1 - 1.4e-17 63.9 0.0 3.4e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CEP08649.1 - 2.5e-15 55.7 2.1 5.7e-15 54.6 1.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CEP08649.1 - 1.7e-08 34.0 0.0 5.8e-08 32.3 0.0 2.0 1 0 0 1 1 1 1 Gelsolin repeat DUF1160 PF06648.6 CEP08650.1 - 0.12 12.1 0.5 0.19 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Myb_DNA-binding PF00249.26 CEP08651.1 - 0.0011 18.9 0.3 0.0023 17.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP08651.1 - 0.056 13.5 0.5 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain ALS_ss_C PF10369.4 CEP08651.1 - 0.058 13.1 0.4 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Small subunit of acetolactate synthase DUF4208 PF13907.1 CEP08651.1 - 0.13 12.4 2.1 0.83 9.9 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) LPP PF04728.8 CEP08652.1 - 2 8.2 5.4 0.78 9.5 0.1 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper RVT_1 PF00078.22 CEP08653.1 - 1.8e-05 24.1 0.1 0.00022 20.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_fiss_reg PF05308.6 CEP08653.1 - 0.19 11.0 0.6 0.26 10.6 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DDE_Tnp_1_7 PF13843.1 CEP08655.1 - 0.019 14.0 0.0 0.023 13.7 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 FGGY_C PF02782.11 CEP08656.1 - 1.2e-64 217.6 3.0 2.6e-64 216.5 1.4 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CEP08656.1 - 7.6e-55 185.8 0.0 1.3e-54 185.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MutS_V PF00488.16 CEP08657.1 - 9.8e-51 172.4 0.2 3.2e-46 157.6 0.1 2.9 1 1 1 2 2 2 2 MutS domain V MutS_III PF05192.13 CEP08657.1 - 7.8e-28 97.6 0.3 1.3e-27 96.8 0.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 CEP08657.1 - 0.014 15.5 0.0 0.059 13.5 0.0 2.1 1 0 0 1 1 1 0 MutS family domain IV AAA PF00004.24 CEP08658.1 - 7.8e-55 184.6 0.1 3.6e-39 133.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CEP08658.1 - 1.2e-10 41.1 0.0 3.3e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CEP08658.1 - 1.8e-09 37.7 0.1 9.3e-07 28.9 0.1 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CEP08658.1 - 3.4e-08 33.6 1.2 0.00072 19.7 0.1 3.9 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 CEP08658.1 - 5.1e-08 32.4 0.2 7.2e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 RuvB_N PF05496.7 CEP08658.1 - 7.4e-08 31.7 0.2 0.0032 16.5 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CEP08658.1 - 1.2e-07 30.8 0.1 0.0097 14.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 CEP08658.1 - 5.5e-07 29.2 0.6 0.057 13.1 0.0 2.9 3 0 0 3 3 3 2 Part of AAA domain AAA_5 PF07728.9 CEP08658.1 - 7e-07 29.0 0.3 0.0012 18.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP08658.1 - 1.2e-06 28.6 0.2 0.025 14.5 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain IstB_IS21 PF01695.12 CEP08658.1 - 1.3e-06 27.9 0.1 0.04 13.3 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.1 CEP08658.1 - 1.4e-06 28.2 0.0 0.055 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CEP08658.1 - 1.4e-06 28.6 0.9 0.012 15.8 0.0 4.1 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 CEP08658.1 - 1.8e-06 27.3 0.2 0.0037 16.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CEP08658.1 - 2.6e-06 27.1 1.7 0.058 13.0 0.0 3.7 3 1 0 3 3 3 2 NACHT domain AAA_17 PF13207.1 CEP08658.1 - 4.9e-06 27.3 0.2 0.0093 16.7 0.0 3.4 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 CEP08658.1 - 1.7e-05 24.9 0.0 0.022 14.9 0.0 3.1 4 0 0 4 4 2 1 RNA helicase Sigma54_activat PF00158.21 CEP08658.1 - 2.7e-05 23.7 0.1 0.29 10.5 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_33 PF13671.1 CEP08658.1 - 2.7e-05 24.0 0.0 0.24 11.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain PhoH PF02562.11 CEP08658.1 - 4.2e-05 22.8 0.0 0.096 11.8 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.1 CEP08658.1 - 4.7e-05 22.8 3.4 0.3 10.4 0.0 4.4 2 2 2 4 4 4 1 AAA domain AAA_24 PF13479.1 CEP08658.1 - 5.6e-05 22.8 2.0 0.044 13.3 0.1 2.7 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 CEP08658.1 - 7.2e-05 22.8 0.6 0.21 11.6 0.2 3.6 3 1 0 3 3 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CEP08658.1 - 0.0001 22.1 0.8 2.3 7.8 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase Zeta_toxin PF06414.7 CEP08658.1 - 0.00011 21.3 0.1 0.43 9.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 CEP08658.1 - 0.00013 21.5 0.2 0.23 11.0 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 CEP08658.1 - 0.00025 20.2 0.6 0.012 14.6 0.0 2.8 2 1 0 2 2 2 1 KaiC ABC_tran PF00005.22 CEP08658.1 - 0.00066 19.9 1.6 0.14 12.4 0.0 3.1 3 0 0 3 3 2 1 ABC transporter AAA_30 PF13604.1 CEP08658.1 - 0.00095 18.7 0.7 0.47 10.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain KAP_NTPase PF07693.9 CEP08658.1 - 0.00098 18.2 0.0 2.4 7.0 0.0 3.2 2 1 1 3 3 3 1 KAP family P-loop domain NB-ARC PF00931.17 CEP08658.1 - 0.0017 17.2 0.4 1.5 7.6 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain T2SE PF00437.15 CEP08658.1 - 0.0035 16.2 0.0 0.97 8.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DEAD PF00270.24 CEP08658.1 - 0.0052 16.2 1.1 20 4.6 0.1 4.5 3 2 2 5 5 5 0 DEAD/DEAH box helicase AAA_3 PF07726.6 CEP08658.1 - 0.006 16.1 0.0 0.077 12.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 CEP08658.1 - 0.014 14.2 0.0 0.63 8.8 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 CEP08658.1 - 0.016 15.1 0.0 0.78 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CEP08658.1 - 0.02 13.8 0.1 1.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 CEP08658.1 - 0.048 13.2 0.1 1.2 8.7 0.0 2.7 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.1 CEP08658.1 - 0.08 12.4 0.3 5 6.7 0.0 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.10 CEP08658.1 - 0.081 12.7 0.7 20 4.9 0.0 2.9 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 CEP08658.1 - 0.089 12.3 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Amidohydro_5 PF13594.1 CEP08658.1 - 0.12 12.2 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase NRDE-2 PF08424.5 CEP08659.1 - 1.1e-06 27.7 2.8 0.00021 20.2 0.1 3.2 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 CEP08659.1 - 1.7e-05 25.0 1.3 0.033 14.5 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP08659.1 - 3.6e-05 24.0 9.0 0.48 11.2 2.8 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP08659.1 - 5.2e-05 23.8 7.6 0.032 14.9 3.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 CEP08659.1 - 0.0002 21.1 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CEP08659.1 - 0.0011 18.7 2.1 0.082 12.8 1.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEP08659.1 - 0.0052 16.3 0.6 0.016 14.8 0.4 1.8 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.1 CEP08659.1 - 0.12 12.1 6.8 45 4.1 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat BOFC_N PF08977.5 CEP08659.1 - 0.21 11.4 2.3 5.1 6.9 0.3 3.5 3 0 0 3 3 3 0 Bypass of Forespore C, N terminal TPR_12 PF13424.1 CEP08659.1 - 1.6 8.7 5.6 17 5.4 2.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP08659.1 - 1.9 9.1 5.3 34 5.1 0.3 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat HAT PF02184.11 CEP08659.1 - 2 8.2 11.6 4 7.2 0.2 4.9 5 2 0 5 5 5 0 HAT (Half-A-TPR) repeat RVT_1 PF00078.22 CEP08661.1 - 3.2e-07 29.9 0.0 6.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CEP08661.1 - 0.042 14.1 0.2 0.75 10.1 0.0 2.6 1 1 1 2 2 2 0 RNase H RVT_1 PF00078.22 CEP08662.1 - 2.2e-25 89.3 0.0 4.3e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP08662.1 - 2.4e-13 49.7 0.1 1.3e-12 47.3 0.1 2.3 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP08662.1 - 2.2e-05 24.5 0.0 5.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BUD22 PF09073.5 CEP08662.1 - 0.11 11.5 0.8 0.15 11.0 0.6 1.1 1 0 0 1 1 1 0 BUD22 PIF1 PF05970.9 CEP08663.1 - 2.6e-19 69.3 0.0 4.2e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP08663.1 - 2.4e-14 53.3 0.0 4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP08663.1 - 0.00055 20.0 0.0 0.0018 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CEP08663.1 - 0.0049 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CEP08663.1 - 0.0061 16.1 0.0 0.021 14.3 0.0 2.0 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 CEP08663.1 - 0.011 15.6 0.0 0.034 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain IR1-M PF12185.3 CEP08663.1 - 0.021 14.5 0.8 0.055 13.1 0.1 2.0 1 1 1 2 2 2 0 Nup358/RanBP2 E3 ligase domain AAA_16 PF13191.1 CEP08663.1 - 0.054 13.4 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CEP08663.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Exo70 PF03081.10 CEP08664.1 - 1e-71 241.6 1.1 1e-71 241.6 0.8 3.9 3 1 0 3 3 3 2 Exo70 exocyst complex subunit BP28CT PF08146.7 CEP08664.1 - 5.2e-40 136.6 0.8 5.2e-40 136.6 0.5 3.9 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CEP08664.1 - 1.5e-14 53.9 3.0 1.5e-14 53.9 2.1 5.1 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 CEP08664.1 - 0.0053 16.7 5.4 18 5.7 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Ribosomal_S13_N PF08069.7 CEP08665.1 - 1.9e-28 98.0 0.1 3.9e-28 97.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CEP08665.1 - 1.7e-22 78.9 0.4 2.5e-22 78.4 0.2 1.4 2 0 0 2 2 2 1 Ribosomal protein S15 zf-A20 PF01754.11 CEP08666.1 - 3.8e-10 39.1 8.4 3.8e-10 39.1 5.8 2.3 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.11 CEP08666.1 - 2.7e-08 33.5 6.2 2.7e-08 33.5 4.3 2.0 2 0 0 2 2 2 1 AN1-like Zinc finger HHV6-IE PF03753.8 CEP08666.1 - 0.013 13.0 11.5 0.014 12.9 8.0 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein SMN PF06003.7 CEP08666.1 - 0.021 13.9 8.8 0.021 13.9 5.7 1.3 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Tweety PF04906.8 CEP08666.1 - 0.046 12.1 0.3 0.061 11.7 0.2 1.1 1 0 0 1 1 1 0 Tweety Ndc1_Nup PF09531.5 CEP08666.1 - 0.67 8.3 12.6 0.78 8.0 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TraG-D_C PF12696.2 CEP08666.1 - 2.4 8.0 5.5 5.5 6.8 3.8 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Alpha_GJ PF03229.8 CEP08666.1 - 4.6 7.5 23.9 6.8 7.0 7.6 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J TFIIA PF03153.8 CEP08666.1 - 5.4 6.7 12.1 6.7 6.4 8.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CEP08666.1 - 7.3 5.8 21.4 8.9 5.5 14.8 1.1 1 0 0 1 1 1 0 Vta1 like DUF4551 PF15087.1 CEP08666.1 - 8.4 4.6 10.5 10 4.3 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SMN PF06003.7 CEP08667.1 - 0.00083 18.5 21.0 0.013 14.6 14.5 2.0 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) Pex14_N PF04695.8 CEP08667.1 - 0.012 15.6 11.3 0.023 14.7 7.8 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CMV_1a PF12467.3 CEP08667.1 - 0.16 12.3 6.7 0.19 12.1 4.6 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Lin-8 PF03353.10 CEP08667.1 - 0.28 10.4 13.6 0.31 10.2 9.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.7 CEP08667.1 - 0.28 10.4 12.6 0.31 10.2 8.7 1.0 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 CEP08667.1 - 1.9 6.0 6.0 2.1 5.9 4.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 CEP08667.1 - 2.4 6.5 16.9 2.5 6.5 11.7 1.0 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 CEP08667.1 - 3.9 6.8 15.7 4.3 6.7 10.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PMSI1 PF15322.1 CEP08667.1 - 6.8 5.6 8.2 11 4.9 5.7 1.3 1 1 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ycf1 PF05758.7 CEP08667.1 - 7.2 4.1 10.2 7.2 4.1 7.1 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CEP08667.1 - 8.6 4.2 19.3 11 3.9 13.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CEP08667.1 - 9 4.0 19.9 11 3.7 13.8 1.0 1 0 0 1 1 1 0 Nop14-like family FYVE PF01363.16 CEP08668.1 - 1.8e-21 75.8 26.7 2.9e-16 59.1 5.9 2.5 2 0 0 2 2 2 2 FYVE zinc finger Rbsn PF11464.3 CEP08668.1 - 0.00023 20.6 0.0 0.00059 19.3 0.0 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 CEP08668.1 - 0.0038 17.0 3.6 0.0038 17.0 2.5 3.9 4 1 1 5 5 5 1 AN1-like Zinc finger IBR PF01485.16 CEP08668.1 - 2.8 7.8 25.6 0.079 12.8 1.5 3.8 2 2 2 4 4 4 0 IBR domain Pyridoxal_deC PF00282.14 CEP08669.1 - 1.7e-19 69.5 0.0 2.4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CEP08669.1 - 3.2e-08 32.7 0.0 6.5e-08 31.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CEP08669.1 - 8.9e-07 28.2 0.1 1.6e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.27 CEP08670.1 - 2.1e-30 103.4 7.8 7.4e-10 38.3 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Ribosomal_L21p PF00829.16 CEP08670.1 - 2.5e-17 62.7 3.0 6.3e-17 61.4 2.1 1.7 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Nup160 PF11715.3 CEP08670.1 - 2.1e-07 29.4 0.2 1.9e-05 23.0 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 LisH PF08513.6 CEP08670.1 - 3.3e-05 23.4 0.0 7.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 LisH PQQ_2 PF13360.1 CEP08670.1 - 0.0025 17.3 0.1 0.24 10.8 0.0 2.8 1 1 2 3 3 3 2 PQQ-like domain AMP-binding PF00501.23 CEP08671.1 - 3.3e-99 332.1 0.2 4.4e-99 331.6 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP08671.1 - 5.8e-20 72.0 0.1 1.6e-19 70.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 CEP08672.1 - 5.7e-68 222.5 13.2 1.9e-10 40.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CEP08672.1 - 1.3e-23 82.9 13.8 2.1e-23 82.3 9.6 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 CEP08672.1 - 5e-05 21.6 2.0 0.041 12.0 0.0 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 CEP08672.1 - 0.0032 16.6 0.1 1.2 8.2 0.0 2.9 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 CEP08672.1 - 0.0058 16.2 0.4 2.2 8.0 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CEP08672.1 - 0.0063 14.8 1.0 0.16 10.2 0.2 2.4 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CEP08672.1 - 0.009 14.8 0.8 4.4 5.9 0.1 3.9 1 1 3 4 4 4 1 Nup133 N terminal like USP8_interact PF08941.5 CEP08672.1 - 0.31 10.3 3.3 0.53 9.5 2.3 1.3 1 0 0 1 1 1 0 USP8 interacting DUF3450 PF11932.3 CEP08672.1 - 0.55 9.4 11.6 0.91 8.7 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 CEP08672.1 - 3.6 6.5 9.2 5.1 6.0 6.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FAD_binding_1 PF00667.15 CEP08673.1 - 8.1e-41 139.8 0.0 1.3e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CEP08673.1 - 9.5e-32 109.9 0.0 1.6e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CEP08673.1 - 2.6e-17 63.3 0.0 5.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 CEP08673.1 - 0.0022 17.4 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain 5_3_exonuc_N PF02739.11 CEP08673.1 - 0.0052 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain Flavodoxin_5 PF12724.2 CEP08673.1 - 0.0057 16.6 0.0 0.076 13.0 0.0 2.2 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_NdrI PF07972.6 CEP08673.1 - 0.053 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 NrdI Flavodoxin like DDE_3 PF13358.1 CEP08674.1 - 5.5e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP08674.1 - 2.6e-05 23.6 0.0 6.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP08674.1 - 0.0073 16.2 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.13 CEP08674.1 - 0.076 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 'Paired box' domain HTH_29 PF13551.1 CEP08674.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Ras PF00071.17 CEP08676.1 - 4.8e-65 217.8 0.6 5.7e-65 217.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP08676.1 - 4e-21 75.7 0.0 6.4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP08676.1 - 3.7e-17 62.1 0.2 4.4e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP08676.1 - 1.4e-07 31.1 0.2 2.9e-07 30.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP08676.1 - 4.7e-07 29.1 0.1 7e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEP08676.1 - 4.4e-05 23.4 0.0 9.3e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CEP08676.1 - 5e-05 22.5 0.0 8.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CEP08676.1 - 0.0015 18.6 0.0 0.0021 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 CEP08676.1 - 0.011 15.3 0.5 0.028 13.9 0.1 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 CEP08676.1 - 0.015 14.2 0.2 0.18 10.7 0.0 2.2 2 1 0 2 2 2 0 Septin AAA_16 PF13191.1 CEP08676.1 - 0.017 15.1 0.1 0.054 13.4 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 CEP08676.1 - 0.02 14.0 0.2 0.056 12.6 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 CEP08676.1 - 0.027 14.7 0.2 0.1 12.8 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CEP08676.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhyH PF05721.8 CEP08676.1 - 0.053 13.5 0.1 0.069 13.1 0.1 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) AAA_5 PF07728.9 CEP08676.1 - 0.057 13.1 0.0 0.08 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CEP08676.1 - 0.069 13.3 0.1 0.3 11.2 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CEP08676.1 - 0.074 12.5 0.1 1.1 8.7 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 CEP08676.1 - 0.18 11.2 0.4 3.1 7.1 0.3 2.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 CEP08676.1 - 1.2 7.7 4.3 13 4.2 0.6 2.7 1 1 1 2 2 2 0 G-protein alpha subunit HTH_psq PF05225.11 CEP08678.1 - 0.00024 20.5 0.1 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_30 PF13556.1 CEP08678.1 - 0.00051 19.5 0.1 0.00097 18.6 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.1 CEP08678.1 - 0.002 17.7 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_1 PF00126.22 CEP08678.1 - 0.0067 16.1 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CENP-B_N PF04218.8 CEP08678.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 CEP08678.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 CEP08678.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain HTH_17 PF12728.2 CEP08678.1 - 0.018 15.2 0.1 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.1 CEP08678.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_8 PF02954.14 CEP08678.1 - 0.024 14.1 0.1 0.077 12.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_3 PF01381.17 CEP08678.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix MarR PF01047.17 CEP08678.1 - 0.064 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_37 PF13744.1 CEP08678.1 - 0.079 12.7 0.2 1.6 8.5 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain RVT_1 PF00078.22 CEP08679.1 - 9.9e-32 110.0 0.0 2.7e-31 108.5 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP08679.1 - 8e-09 35.7 0.5 2e-08 34.5 0.4 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CEP08679.1 - 4.6e-07 30.0 1.0 1.2e-06 28.7 0.7 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 CEP08679.1 - 0.013 15.4 1.2 0.013 15.4 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle Peptidase_M50 PF02163.17 CEP08682.1 - 5.4e-08 32.0 0.1 4.2e-07 29.1 0.1 2.4 1 1 0 1 1 1 1 Peptidase family M50 ER_lumen_recept PF00810.13 CEP08683.1 - 3.5e-37 128.1 3.6 5.8e-37 127.4 2.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CEP08683.1 - 0.061 12.8 1.3 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 PQ loop repeat EF-hand_7 PF13499.1 CEP08684.1 - 0.17 12.0 0.7 1.3 9.2 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain pair Chromo PF00385.19 CEP08686.1 - 1.4e-09 37.5 1.6 2.5e-09 36.6 1.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP08686.1 - 0.00012 21.6 0.4 0.0012 18.5 0.1 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain HECT_2 PF09814.4 CEP08687.1 - 0.039 12.6 0.1 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Asp_protease_2 PF13650.1 CEP08688.1 - 5.6e-08 33.1 0.1 1.5e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CEP08688.1 - 1.1e-06 28.2 11.1 4.7e-06 26.2 1.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CEP08688.1 - 0.013 15.1 8.9 0.091 12.5 1.3 2.7 1 1 1 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.1 CEP08688.1 - 0.013 15.2 0.0 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-CCHC_4 PF14392.1 CEP08688.1 - 5 6.8 8.7 1.4 8.6 0.8 3.1 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 CEP08689.1 - 0.00016 21.4 1.5 0.00036 20.3 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEP08689.1 - 0.0094 15.9 0.3 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-C2H2_2 PF12756.2 CEP08689.1 - 0.076 13.1 0.4 0.33 11.0 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RVT_1 PF00078.22 CEP08690.1 - 1.6e-17 63.5 0.0 4.5e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP08690.1 - 2.5e-05 24.6 0.0 0.00026 21.4 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease RNase_H PF00075.19 CEP08690.1 - 0.0017 18.7 0.1 0.0039 17.5 0.1 1.5 1 0 0 1 1 1 1 RNase H gag-asp_proteas PF13975.1 CEP08690.1 - 0.0024 17.6 0.0 0.0083 15.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2328 PF10090.4 CEP08690.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2328) Asp_protease PF09668.5 CEP08690.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease WD40 PF00400.27 CEP08691.1 - 2.6e-17 61.9 3.0 4.3e-08 32.7 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 CEP08691.1 - 0.015 13.4 0.3 0.025 12.7 0.2 1.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CEP08691.1 - 0.024 13.4 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like BBS2_Mid PF14783.1 CEP08691.1 - 0.062 13.0 0.0 0.52 10.0 0.0 1.9 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region bZIP_2 PF07716.10 CEP08692.1 - 1.9e-10 40.4 11.6 1.9e-10 40.4 8.0 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP08692.1 - 0.00013 21.8 8.2 0.00013 21.8 5.7 2.7 2 0 0 2 2 2 1 bZIP transcription factor IFP_35_N PF07334.8 CEP08692.1 - 0.081 12.8 6.2 0.07 13.1 1.2 2.8 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PspB PF06667.7 CEP08692.1 - 2.2 8.2 5.7 0.33 10.9 0.7 2.1 2 0 0 2 2 2 0 Phage shock protein B CENP-B_dimeris PF09026.5 CEP08692.1 - 8.2 6.7 12.1 9.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MCM PF00493.18 CEP08693.1 - 4.1e-132 439.9 0.0 6.8e-132 439.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CEP08693.1 - 1.1e-25 90.4 0.3 6.4e-25 87.9 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CEP08693.1 - 2.3e-07 30.1 0.0 1.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CEP08693.1 - 2.5e-06 27.2 0.1 1.1e-05 25.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CEP08693.1 - 0.026 14.1 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CEP08693.1 - 0.096 12.1 0.0 0.79 9.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Fer2 PF00111.22 CEP08694.1 - 6.4e-08 32.2 1.3 8e-08 31.9 0.9 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Dehydrin PF00257.14 CEP08695.1 - 0.0028 18.0 1.3 0.0055 17.0 0.9 1.6 1 0 0 1 1 1 1 Dehydrin Tfb4 PF03850.9 CEP08695.1 - 0.39 9.9 2.6 0.79 8.9 1.8 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 AAA_2 PF07724.9 CEP08696.1 - 3.2e-54 183.4 6.6 3.2e-51 173.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CEP08696.1 - 1.1e-27 96.8 0.1 1.1e-14 54.7 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CEP08696.1 - 3.4e-23 81.3 0.1 3.4e-23 81.3 0.0 3.1 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CEP08696.1 - 6.3e-20 71.3 2.5 1.2e-11 44.5 0.0 4.0 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 CEP08696.1 - 7e-17 61.0 0.0 2.2e-08 33.8 0.1 3.2 2 0 0 2 2 2 2 Clp amino terminal domain AAA_16 PF13191.1 CEP08696.1 - 1.5e-15 57.6 3.6 4.5e-06 26.7 0.0 5.6 4 2 1 6 6 6 3 AAA ATPase domain AAA_22 PF13401.1 CEP08696.1 - 2.6e-10 40.5 0.1 0.001 19.1 0.0 4.0 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CEP08696.1 - 4.2e-10 39.3 0.1 1.8e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 CEP08696.1 - 1.2e-08 34.8 0.0 0.0078 16.1 0.0 3.7 3 1 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 CEP08696.1 - 1.7e-07 30.5 0.1 0.007 15.5 0.1 3.5 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CEP08696.1 - 5.3e-07 30.4 7.0 0.025 15.4 0.0 4.0 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CEP08696.1 - 6.1e-07 29.0 0.0 0.042 13.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CEP08696.1 - 3.2e-05 23.5 0.0 0.032 13.9 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain AAA_18 PF13238.1 CEP08696.1 - 5.7e-05 23.4 9.9 0.0068 16.7 0.0 4.6 5 1 1 6 6 3 2 AAA domain MobB PF03205.9 CEP08696.1 - 7.2e-05 22.5 0.0 0.069 12.8 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CEP08696.1 - 9e-05 22.1 0.0 0.027 14.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CEP08696.1 - 0.0002 21.5 0.0 0.75 9.9 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Torsin PF06309.6 CEP08696.1 - 0.00038 20.3 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Torsin AAA_28 PF13521.1 CEP08696.1 - 0.00055 19.9 0.1 3.1 7.7 0.0 4.0 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CEP08696.1 - 0.00088 19.5 0.1 0.36 11.1 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.1 CEP08696.1 - 0.0025 17.4 0.0 0.32 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.1 CEP08696.1 - 0.003 17.2 0.2 3.7 7.1 0.0 3.9 4 0 0 4 4 4 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 CEP08696.1 - 0.0041 16.7 0.0 1.4 8.5 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CEP08696.1 - 0.0042 16.5 0.6 1.3 8.4 0.0 3.8 3 2 1 4 4 4 1 AAA-like domain Arch_ATPase PF01637.13 CEP08696.1 - 0.0043 16.7 13.2 0.15 11.6 0.1 5.0 3 2 1 4 4 4 2 Archaeal ATPase DUF258 PF03193.11 CEP08696.1 - 0.0044 16.2 0.0 2.3 7.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CEP08696.1 - 0.0045 16.9 0.0 0.87 9.5 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 CEP08696.1 - 0.0052 16.2 0.0 2.9 7.2 0.0 3.1 2 1 1 3 3 3 1 AAA domain SRP54 PF00448.17 CEP08696.1 - 0.0088 15.5 0.2 1 8.7 0.0 3.0 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain ResIII PF04851.10 CEP08696.1 - 0.011 15.6 0.0 1 9.1 0.0 3.5 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 CEP08696.1 - 0.012 15.3 0.1 4.9 6.8 0.0 3.6 3 0 0 3 3 3 0 NTPase ATP_bind_1 PF03029.12 CEP08696.1 - 0.015 14.8 0.0 0.64 9.5 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CEP08696.1 - 0.021 14.3 0.0 1.5 8.2 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 CEP08696.1 - 0.023 14.5 0.0 3 7.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain BLOC1_2 PF10046.4 CEP08696.1 - 0.035 14.2 5.5 0.068 13.3 2.6 2.5 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0079 PF02367.12 CEP08696.1 - 0.068 12.7 0.0 16 5.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 CEP08696.1 - 0.15 11.5 0.0 7.9 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CEP08696.1 - 1.5 9.1 19.4 0.4 10.9 1.3 4.5 4 1 0 4 4 4 0 AAA domain IncA PF04156.9 CEP08696.1 - 5.4 6.5 17.4 1.7 8.2 9.3 2.2 2 1 0 2 2 1 0 IncA protein UAA PF08449.6 CEP08697.1 - 3.1e-79 266.0 15.6 3.6e-79 265.8 10.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP08697.1 - 6.5e-11 42.3 13.5 2.9e-09 37.0 2.2 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CEP08697.1 - 3.8e-06 27.0 13.2 2e-05 24.7 1.6 2.7 3 1 0 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CEP08697.1 - 0.00015 20.9 7.6 0.15 11.1 0.1 3.1 1 1 2 3 3 3 2 Nucleotide-sugar transporter TPT PF03151.11 CEP08697.1 - 0.0046 16.6 5.0 0.0046 16.6 3.5 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family AAA PF00004.24 CEP08698.1 - 5e-54 182.0 0.0 9.2e-37 126.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CEP08698.1 - 3e-07 30.4 0.0 0.00052 19.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CEP08698.1 - 2.4e-06 27.6 0.0 0.00054 19.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CEP08698.1 - 4.8e-06 26.7 0.3 0.0044 17.1 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP08698.1 - 6.1e-05 23.8 0.1 0.00026 21.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CEP08698.1 - 0.00018 20.6 0.0 0.00054 19.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEP08698.1 - 0.00065 19.7 0.5 0.02 14.9 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 CEP08698.1 - 0.00074 18.9 0.1 0.0026 17.2 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 CEP08698.1 - 0.001 18.4 0.1 0.0066 15.8 0.0 2.1 2 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CEP08698.1 - 0.0013 18.4 0.0 0.085 12.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CEP08698.1 - 0.0019 18.4 0.0 0.0051 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP08698.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CEP08698.1 - 0.0055 16.4 0.1 0.15 11.7 0.0 2.5 3 0 0 3 3 2 1 Archaeal ATPase TIP49 PF06068.8 CEP08698.1 - 0.0078 14.9 1.9 0.033 12.9 0.1 2.8 3 1 1 4 4 4 1 TIP49 C-terminus AAA_24 PF13479.1 CEP08698.1 - 0.0097 15.5 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CEP08698.1 - 0.013 15.8 1.0 0.035 14.4 0.0 2.1 2 1 1 3 3 2 0 AAA domain ResIII PF04851.10 CEP08698.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CEP08698.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.24 CEP08698.1 - 0.014 14.8 0.0 5 6.5 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase Bac_DnaA PF00308.13 CEP08698.1 - 0.015 14.9 0.0 0.051 13.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial dnaA protein T2SE PF00437.15 CEP08698.1 - 0.018 13.9 0.1 0.054 12.3 0.0 1.9 1 1 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 CEP08698.1 - 0.02 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 CEP08698.1 - 0.029 13.8 0.0 0.45 9.9 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain IPT PF01745.11 CEP08698.1 - 0.035 13.2 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_28 PF13521.1 CEP08698.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CEP08698.1 - 0.082 12.0 0.0 0.19 10.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CEP08698.1 - 0.083 12.5 0.6 0.31 10.6 0.1 2.2 3 0 0 3 3 2 0 NACHT domain WD40 PF00400.27 CEP08699.1 - 8.9e-26 88.7 15.3 6.3e-08 32.2 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CEP08699.1 - 1.7e-06 27.8 0.7 0.004 16.8 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CEP08699.1 - 0.0018 17.4 0.1 0.5 9.4 0.0 2.3 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 CEP08699.1 - 0.14 9.9 8.6 1.2 6.8 5.9 2.3 1 1 0 1 1 1 0 IKI3 family rpo132 PF12415.3 CEP08699.1 - 0.23 10.4 0.9 0.53 9.2 0.1 2.0 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase NARP1 PF12569.3 CEP08700.1 - 3.5e-179 596.8 24.8 3.5e-179 596.8 17.2 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CEP08700.1 - 2.6e-14 52.5 22.6 0.00026 20.5 3.1 8.4 7 1 1 8 8 8 5 TPR repeat TPR_2 PF07719.12 CEP08700.1 - 5.4e-13 47.7 27.2 8.6e-05 22.1 1.4 9.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.1 CEP08700.1 - 9.6e-13 47.5 19.1 0.19 12.4 0.0 10.9 7 5 7 14 14 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEP08700.1 - 6.3e-12 45.6 26.4 0.038 14.3 0.1 8.8 8 3 1 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP08700.1 - 2.3e-11 44.0 21.4 0.12 13.0 0.6 9.5 8 3 2 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 CEP08700.1 - 2e-10 40.4 15.6 0.0097 15.8 0.0 7.6 6 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 CEP08700.1 - 5.8e-08 32.4 0.1 0.011 15.5 0.0 5.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP08700.1 - 4.8e-07 29.8 5.6 1.3 9.6 0.0 8.4 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP08700.1 - 1.2e-06 28.2 13.3 0.4 11.0 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP08700.1 - 1.6e-06 27.4 22.0 0.0052 16.4 0.4 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 CEP08700.1 - 2e-06 27.1 19.2 0.0073 15.8 2.3 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEP08700.1 - 3.6e-05 23.2 2.1 0.14 12.0 0.1 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CEP08700.1 - 0.00024 20.2 18.8 0.0014 17.7 0.8 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat PIG-L PF02585.12 CEP08700.1 - 0.031 14.8 0.0 28 5.2 0.0 3.7 2 1 0 2 2 2 0 GlcNAc-PI de-N-acetylase TPR_4 PF07721.9 CEP08700.1 - 0.049 14.0 0.0 3.4 8.3 0.0 3.8 5 0 0 5 5 2 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 CEP08701.1 - 1.2e-47 162.2 0.0 1.4e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEP08701.1 - 5.6e-08 31.8 0.1 7.5e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) AXE1 PF05448.7 CEP08701.1 - 0.0016 17.0 0.0 0.0022 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.23 CEP08701.1 - 0.0033 16.2 0.0 0.03 13.0 0.1 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 CEP08701.1 - 0.0058 15.8 0.0 0.009 15.2 0.0 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEP08701.1 - 0.023 14.4 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP08701.1 - 0.041 13.7 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Acyl-CoA_dh_1 PF00441.19 CEP08702.1 - 6.3e-32 110.7 1.0 9e-32 110.2 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEP08702.1 - 1.2e-16 59.9 0.1 3.9e-16 58.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CEP08702.1 - 3.5e-15 56.4 1.1 6.5e-15 55.5 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEP08702.1 - 4.1e-14 53.1 0.0 8.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 CEP08702.1 - 0.0024 17.3 0.0 0.0058 16.0 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal START PF01852.14 CEP08703.1 - 2.9e-24 85.5 0.5 6.1e-14 51.8 0.0 2.5 2 0 0 2 2 2 2 START domain Pkinase PF00069.20 CEP08704.1 - 2.8e-71 239.7 1.6 6.6e-71 238.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08704.1 - 7.9e-41 139.8 0.0 7.3e-40 136.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP08704.1 - 3.7e-05 23.5 0.0 0.00013 21.7 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CEP08704.1 - 5.3e-05 22.3 0.1 0.00014 21.0 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CEP08704.1 - 0.00091 18.2 0.0 0.0019 17.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 CEP08704.1 - 0.013 14.7 0.5 0.026 13.7 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 CEP08704.1 - 0.04 13.2 0.0 0.04 13.2 0.0 2.9 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL SNF2_N PF00176.18 CEP08705.1 - 1.8e-50 171.4 0.7 4.1e-49 167.0 0.1 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP08705.1 - 2e-13 49.9 0.0 5.8e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP08705.1 - 1.1e-10 41.5 0.1 4.9e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEP08705.1 - 6.1e-05 22.5 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase NDT80_PhoG PF05224.7 CEP08706.1 - 1.4e-37 129.5 0.0 5.4e-37 127.6 0.0 2.0 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pkinase PF00069.20 CEP08707.1 - 1.4e-25 89.9 0.0 3.4e-24 85.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08707.1 - 2.4e-08 33.3 0.0 4.3e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 CEP08708.1 - 6.4e-25 87.5 7.7 6.4e-25 87.5 5.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP08708.1 - 9.2 4.7 21.6 0.077 11.5 1.8 2.8 2 2 0 2 2 2 0 Sugar (and other) transporter RhoGEF PF00621.15 CEP08709.1 - 2.9e-43 147.8 6.2 2.9e-43 147.8 4.3 1.9 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.6 CEP08709.1 - 8.1e-31 105.9 0.5 2.9e-30 104.1 0.1 2.2 2 0 0 2 2 2 1 CDC24 Calponin PH_10 PF15411.1 CEP08709.1 - 1.5e-20 73.5 1.5 3e-20 72.5 1.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 CEP08709.1 - 1.3e-12 47.1 0.4 4.2e-12 45.5 0.3 1.8 1 0 0 1 1 1 1 PB1 domain CH PF00307.26 CEP08709.1 - 0.045 13.8 2.5 0.064 13.3 0.1 2.5 3 0 0 3 3 3 0 Calponin homology (CH) domain PH PF00169.24 CEP08709.1 - 0.15 12.2 4.4 0.082 13.1 0.8 2.2 2 0 0 2 2 2 0 PH domain HSCB_C PF07743.8 CEP08710.1 - 1.4e-15 57.4 3.7 1.4e-15 57.4 2.5 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CEP08710.1 - 4.2e-10 39.2 1.1 1.1e-09 37.9 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.1 CEP08710.1 - 0.022 13.9 0.5 0.034 13.3 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 CEP08710.1 - 0.11 12.2 3.1 0.19 11.5 2.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon NDK PF00334.14 CEP08711.1 - 5.9e-45 152.3 0.2 1.8e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 Nucleoside diphosphate kinase PIF1 PF05970.9 CEP08713.1 - 3.4e-14 52.5 0.0 3.6e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP08713.1 - 9.8e-14 51.3 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP08713.1 - 2.4e-06 27.7 0.1 6.6e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CEP08713.1 - 0.00025 20.6 0.0 0.00045 19.7 0.0 1.4 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CEP08713.1 - 0.00028 20.5 0.1 0.0036 16.9 0.1 2.0 1 1 0 1 1 1 1 Helicase AAA_10 PF12846.2 CEP08713.1 - 0.0015 18.0 0.1 0.0022 17.4 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 CEP08713.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 CEP08713.1 - 0.015 14.3 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain TK PF00265.13 CEP08713.1 - 0.02 14.4 0.0 0.024 14.2 0.0 1.0 1 0 0 1 1 1 0 Thymidine kinase AAA_16 PF13191.1 CEP08713.1 - 0.027 14.4 0.0 0.027 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 CEP08713.1 - 0.028 13.3 0.3 0.14 11.1 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 CEP08713.1 - 0.03 14.2 0.0 0.065 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CEP08713.1 - 0.037 14.2 0.0 0.058 13.5 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEP08713.1 - 0.046 14.5 0.1 0.05 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP08713.1 - 0.062 12.9 0.0 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CEP08713.1 - 0.072 13.2 0.1 0.099 12.8 0.1 1.5 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 CEP08713.1 - 0.078 12.3 0.1 0.093 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CEP08713.1 - 0.081 12.8 0.0 0.097 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CEP08713.1 - 0.081 12.6 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 CEP08713.1 - 0.082 13.2 0.2 0.14 12.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter DUF87 PF01935.12 CEP08713.1 - 0.088 12.6 0.1 0.093 12.5 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF2791 PF10923.3 CEP08713.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Thymidylate_kin PF02223.12 CEP08713.1 - 0.12 11.7 0.0 0.43 9.9 0.0 1.7 1 1 1 2 2 2 0 Thymidylate kinase DUF258 PF03193.11 CEP08713.1 - 0.12 11.5 0.1 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CEP08713.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Acyl-thio_N PF12590.3 CEP08714.1 - 6.9 7.1 6.7 5.7 7.4 2.1 2.1 1 1 1 2 2 2 0 Acyl-ATP thioesterase Retrotrans_gag PF03732.12 CEP08715.1 - 3.3e-05 23.8 0.4 0.00018 21.4 0.0 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 CEP08715.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CEP08715.1 - 0.0041 17.5 0.0 0.0084 16.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RP-C_C PF11800.3 CEP08715.1 - 0.54 9.9 2.8 3.2 7.4 1.7 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region RVT_1 PF00078.22 CEP08716.1 - 7.3e-21 74.5 0.0 1.3e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP08716.1 - 2.3e-05 24.8 0.0 8.7e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP08716.1 - 0.00094 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.1 CEP08717.1 - 0.00049 19.7 7.1 0.0016 18.1 0.5 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 CEP08717.1 - 0.00096 18.9 14.4 0.012 15.4 1.2 2.4 1 1 1 2 2 2 2 Zinc knuckle DUF1340 PF07067.6 CEP08717.1 - 0.076 12.1 0.7 0.13 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) zf-CCHC_4 PF14392.1 CEP08717.1 - 0.14 11.8 11.2 0.09 12.4 1.0 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CEP08717.1 - 0.22 11.2 6.1 3 7.6 0.5 2.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 CEP08718.1 - 4.1e-06 26.4 18.7 4.4e-05 23.1 3.4 2.4 2 0 0 2 2 2 2 Zinc knuckle DUF4559 PF15112.1 CEP08718.1 - 0.61 9.1 8.9 0.29 10.2 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Exo_endo_phos PF03372.18 CEP08719.1 - 0.004 17.1 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP08719.1 - 0.04 13.5 0.1 0.091 12.3 0.0 1.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase FH2 PF02181.18 CEP08720.1 - 2.6e-68 230.5 13.3 2.6e-68 230.5 9.2 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CEP08720.1 - 8e-30 103.5 1.2 6.6e-29 100.6 0.0 2.8 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CEP08720.1 - 9.2e-26 90.4 3.5 1.4e-25 89.8 0.3 2.7 2 1 0 2 2 2 1 Diaphanous FH3 Domain GATase PF00117.23 CEP08721.1 - 2.2e-11 43.6 0.0 2.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.11 CEP08721.1 - 9.5e-06 24.5 0.0 1.7e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Homoserine O-succinyltransferase Peptidase_C26 PF07722.8 CEP08721.1 - 9.6e-06 25.1 1.0 3.3e-05 23.4 0.7 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 CEP08721.1 - 0.00098 18.7 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 CEP08721.1 - 0.0028 17.1 0.0 0.008 15.6 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family BPL_N PF09825.4 CEP08721.1 - 0.084 11.6 0.0 0.22 10.2 0.0 1.5 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DLH PF01738.13 CEP08721.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family PPTA PF01239.17 CEP08722.1 - 1.9e-38 128.1 13.6 4.3e-07 28.9 0.0 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 CEP08722.1 - 0.012 15.7 1.5 4.2 7.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat tRNA-synt_2b PF00587.20 CEP08723.1 - 2.4e-22 79.3 0.0 4e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEP08723.1 - 3.2e-05 23.8 0.1 7.7e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain UvrD_C_2 PF13538.1 CEP08725.1 - 7e-05 22.9 0.0 8.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MULE PF10551.4 CEP08726.1 - 4.2e-08 33.2 0.3 1.4e-07 31.6 0.1 1.9 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_IS240 PF13610.1 CEP08726.1 - 0.02 14.8 0.2 0.046 13.7 0.1 1.8 1 1 0 1 1 1 0 DDE domain Transposase_mut PF00872.13 CEP08726.1 - 1.3 7.5 4.2 4.6 5.6 2.9 1.7 1 1 0 1 1 1 0 Transposase, Mutator family ERp29 PF07749.7 CEP08727.1 - 0.056 14.0 0.0 0.095 13.3 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain RVT_1 PF00078.22 CEP08728.1 - 2.5e-19 69.5 0.2 5.3e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP08728.1 - 6.4e-09 36.2 0.3 1.6e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 CEP08728.1 - 1.6e-08 34.1 0.0 3.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP08728.1 - 1.4e-06 28.0 0.0 4.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CEP08728.1 - 0.0004 20.3 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP08728.1 - 0.0025 17.5 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 CEP08731.1 - 3.9e-32 111.0 0.0 7.1e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP08731.1 - 7e-05 22.9 0.0 0.00023 21.2 0.0 1.8 1 1 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CEP08731.1 - 0.00033 20.5 0.6 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP08731.1 - 0.0025 18.0 0.1 1.9 8.7 0.0 3.5 4 0 0 4 4 4 1 Helix-turn-helix domain rve PF00665.21 CEP08731.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DDE_1 PF03184.14 CEP08731.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Retrotrans_gag PF03732.12 CEP08732.1 - 0.00082 19.3 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Helitron_like_N PF14214.1 CEP08734.1 - 5.2e-14 52.3 0.1 3.9e-08 33.2 0.0 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus RVP_2 PF08284.6 CEP08736.1 - 1.1e-09 38.2 0.1 5.5e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP08736.1 - 8.4e-07 28.7 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CEP08736.1 - 0.00064 20.1 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CEP08737.1 - 4.5e-07 29.4 13.1 0.0005 19.8 1.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP08737.1 - 0.0059 16.2 7.7 0.34 10.6 1.1 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP08737.1 - 0.018 14.5 5.1 0.018 14.5 3.5 2.2 1 1 1 2 2 2 0 Zinc knuckle Helitron_like_N PF14214.1 CEP08738.1 - 5.9e-08 32.6 0.1 4.6e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 CEP08738.1 - 0.059 12.9 0.8 0.29 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3296) Rotamase_3 PF13616.1 CEP08740.1 - 0.0022 18.2 1.2 0.0035 17.5 0.6 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain BicD PF09730.4 CEP08740.1 - 0.14 10.5 4.4 0.14 10.5 2.4 1.3 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D MULE PF10551.4 CEP08743.1 - 1.9e-09 37.5 0.2 5.5e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF2404 PF10296.4 CEP08744.1 - 3.3e-24 84.8 0.0 8.1e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF3974 PF13120.1 CEP08744.1 - 0.0021 17.8 0.1 0.17 11.6 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3974) HATPase_c PF02518.21 CEP08745.1 - 1.6e-29 101.8 0.2 3.2e-29 100.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEP08745.1 - 1.7e-19 69.9 0.0 7.1e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 CEP08745.1 - 4.7e-18 64.9 0.6 1.3e-17 63.5 0.0 2.2 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 CEP08745.1 - 4.2e-17 62.7 0.0 1.2e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.20 CEP08745.1 - 7.3e-12 44.9 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_2 PF13185.1 CEP08745.1 - 7.6e-11 42.6 0.0 2.8e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 CEP08745.1 - 1.1e-08 35.2 0.0 2.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 CEP08745.1 - 4.6e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.17 CEP08745.1 - 0.00011 21.1 0.0 0.00025 20.0 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain Pkinase_Tyr PF07714.12 CEP08745.1 - 0.0002 20.5 0.0 0.00041 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_29 PF13555.1 CEP08745.1 - 0.0059 16.1 0.0 0.022 14.2 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CEP08745.1 - 0.0098 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 CEP08745.1 - 0.075 12.2 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 CEP08745.1 - 0.18 11.3 0.1 0.41 10.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_2 PF00152.15 CEP08746.1 - 1.9e-120 401.6 0.1 2.3e-120 401.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CEP08746.1 - 8.7e-06 25.1 0.9 4e-05 22.9 0.1 2.5 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CEP08746.1 - 1.5e-05 24.7 0.0 6e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CEP08746.1 - 0.00012 21.6 0.3 0.048 13.2 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) GAD PF02938.9 CEP08746.1 - 0.0027 17.8 0.0 0.018 15.2 0.0 2.3 2 1 0 2 2 2 1 GAD domain rve PF00665.21 CEP08747.1 - 5.2e-20 71.7 0.0 1.3e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Bul1_N PF04425.7 CEP08748.1 - 0.0051 15.4 0.5 0.0052 15.3 0.4 1.0 1 0 0 1 1 1 1 Bul1 N terminus CYSTM PF12734.2 CEP08749.1 - 0.057 13.5 3.7 1.6 8.8 0.7 2.5 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Opi1 PF08618.5 CEP08749.1 - 0.14 11.0 2.4 0.16 10.8 1.6 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 KdgM PF06178.8 CEP08750.1 - 0.063 12.7 2.3 0.096 12.1 1.6 1.3 1 1 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) DUF2058 PF09831.4 CEP08752.1 - 0.013 15.3 0.1 0.02 14.7 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) NIR_SIR PF01077.17 CEP08752.1 - 0.036 13.4 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Sporozoite_P67 PF05642.6 CEP08752.1 - 0.27 9.0 2.5 0.32 8.8 1.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1340 PF07067.6 CEP08753.1 - 0.093 11.8 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Osmo_CC PF08946.5 CEP08753.1 - 0.21 11.6 7.7 6.8 6.8 0.0 3.2 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Vir_act_alpha_C PF10400.4 CEP08753.1 - 2 8.8 4.9 5 7.5 0.7 2.3 1 1 1 2 2 2 0 Virulence activator alpha C-term Phage_int_SAM_4 PF13495.1 CEP08756.1 - 0.011 16.0 2.9 10 6.4 0.2 3.2 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Raptor_N PF14538.1 CEP08758.1 - 1.2e-65 220.1 0.0 1.2e-65 220.1 0.0 2.2 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 CEP08758.1 - 1.5e-10 40.5 3.1 0.079 12.8 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT_2 PF13646.1 CEP08758.1 - 7e-09 35.8 0.1 4.7e-05 23.6 0.0 3.7 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CEP08758.1 - 9.7e-08 31.4 8.3 0.0041 17.0 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 CEP08758.1 - 0.0054 17.1 0.7 0.8 10.2 0.0 4.1 3 1 1 4 4 4 2 HEAT-like repeat BBS2_Mid PF14783.1 CEP08758.1 - 0.02 14.6 0.1 4 7.2 0.0 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF4441 PF14536.1 CEP08758.1 - 0.049 13.6 3.9 0.17 11.9 2.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) RVT_1 PF00078.22 CEP08760.1 - 3.2e-08 33.2 0.0 3.7e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIG-L PF02585.12 CEP08761.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase DDE_Tnp_4 PF13359.1 CEP08762.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 CEP08762.1 - 0.044 13.3 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease RVT_1 PF00078.22 CEP08763.1 - 4.3e-19 68.7 0.0 5.3e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAP1 PF08601.5 CEP08764.1 - 0.047 13.3 1.2 0.055 13.1 0.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 FlxA PF14282.1 CEP08765.1 - 1.7 8.6 5.6 6.1 6.8 2.1 2.5 2 0 0 2 2 2 0 FlxA-like protein AreA_N PF07573.6 CEP08766.1 - 0.18 12.3 1.7 0.18 12.3 1.2 1.1 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus RVP_2 PF08284.6 CEP08767.1 - 6.7e-05 22.8 0.1 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease PI3K_rbd PF00794.13 CEP08767.1 - 0.016 15.1 0.3 0.022 14.6 0.2 1.3 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Retrotrans_gag PF03732.12 CEP08768.1 - 8.4e-05 22.5 0.0 0.00036 20.5 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein RHH_1 PF01402.16 CEP08768.1 - 0.073 12.9 0.0 0.54 10.2 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family zf-RVT PF13966.1 CEP08769.1 - 0.035 14.4 0.1 0.068 13.4 0.1 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.22 CEP08770.1 - 3.6e-18 65.7 0.2 8.6e-18 64.4 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP08771.1 - 0.037 13.6 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DNA_pol_A_exo1 PF01612.15 CEP08772.1 - 0.00093 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease NPP1 PF05630.6 CEP08773.1 - 0.085 12.5 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) DUF3324 PF11797.3 CEP08774.1 - 0.12 12.1 1.3 0.16 11.6 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) PapD_N PF00345.15 CEP08775.1 - 0.12 12.1 0.0 0.99 9.1 0.0 2.0 1 1 1 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain rve PF00665.21 CEP08776.1 - 6.5e-06 26.2 0.0 2e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain Tantalus PF15386.1 CEP08776.1 - 0.1 12.4 0.6 0.26 11.0 0.4 1.7 1 0 0 1 1 1 0 Drosophila Tantalus-like RVT_1 PF00078.22 CEP08777.1 - 4e-08 32.8 0.1 1.1e-06 28.2 0.0 2.6 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP08779.1 - 4.6e-05 23.5 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP08781.1 - 1.4e-06 27.7 0.0 1.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4654 PF15547.1 CEP08781.1 - 0.049 13.9 0.0 0.057 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4654) Phage_integrase PF00589.17 CEP08782.1 - 2.1e-07 30.7 0.4 3.9e-07 29.8 0.3 1.4 1 1 0 1 1 1 1 Phage integrase family TA0956 PF11513.3 CEP08782.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 DUF406 PF04175.7 CEP08783.1 - 0.13 12.6 1.9 0.25 11.8 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF406) Aldedh PF00171.17 CEP08785.1 - 5.1e-164 545.9 0.0 5.7e-164 545.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CEP08785.1 - 4.9e-05 22.6 0.1 0.22 10.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 CEP08785.1 - 0.0056 15.4 0.1 0.016 13.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Toprim_3 PF13362.1 CEP08785.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Glycos_transf_4 PF00953.16 CEP08786.1 - 3.7e-30 104.8 14.7 3.7e-30 104.8 10.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 Dpy-30 PF05186.8 CEP08786.1 - 1.1e-14 53.5 0.0 2e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif PP2C PF00481.16 CEP08787.1 - 9.8e-64 215.1 0.1 1.5e-63 214.6 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CEP08787.1 - 0.00025 20.4 0.0 0.00059 19.2 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C BH4 PF02180.12 CEP08787.1 - 0.089 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 mRNA_triPase PF02940.10 CEP08788.1 - 1.3e-51 175.4 4.3 1.7e-51 175.0 3.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain YwpF PF14183.1 CEP08788.1 - 0.077 12.7 0.2 0.21 11.2 0.1 1.7 2 0 0 2 2 2 0 YwpF-like protein Ras PF00071.17 CEP08789.1 - 1.4e-53 180.5 0.0 1.9e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP08789.1 - 1.1e-14 54.9 0.0 2.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP08789.1 - 6.6e-08 31.9 0.0 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Aldedh PF00171.17 CEP08789.1 - 1.4e-07 30.2 0.0 2.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SRPRB PF09439.5 CEP08789.1 - 0.0055 15.9 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEP08789.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ank_5 PF13857.1 CEP08790.1 - 1.1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CEP08790.1 - 0.034 13.9 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.1 CEP08790.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Shugoshin_N PF07558.6 CEP08790.1 - 0.2 11.3 0.3 0.2 11.3 0.2 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region FliD_N PF02465.13 CEP08790.1 - 1.9 8.9 5.8 0.8 10.1 0.9 2.5 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Striatin PF08232.7 CEP08790.1 - 2 8.7 8.5 0.72 10.1 0.9 2.7 2 1 0 2 2 2 0 Striatin family DEAD PF00270.24 CEP08791.1 - 2.3e-49 167.1 0.0 1.4e-48 164.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP08791.1 - 8.8e-28 95.9 0.0 3.3e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP08791.1 - 0.00033 20.5 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CEP08791.1 - 0.00079 18.3 0.0 0.001 17.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 CEP08791.1 - 0.04 12.3 0.0 0.13 10.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) GTP_EFTU PF00009.22 CEP08792.1 - 4.3e-39 133.8 0.3 6.8e-39 133.2 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CEP08792.1 - 4.6e-35 119.5 0.2 1.2e-34 118.1 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CEP08792.1 - 2.1e-08 34.1 1.9 2.1e-08 34.1 1.3 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEP08792.1 - 0.0067 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEP08792.1 - 0.031 14.1 0.3 0.13 12.1 0.2 2.2 1 1 0 1 1 1 0 Dynamin family Borrelia_orfD PF02999.9 CEP08792.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Borrelia orf-D family Ribophorin_I PF04597.9 CEP08793.1 - 1.7e-131 438.7 10.1 1.9e-131 438.5 7.0 1.0 1 0 0 1 1 1 1 Ribophorin I DIOX_N PF14226.1 CEP08794.1 - 6.3e-33 113.7 0.0 1.8e-32 112.3 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CEP08794.1 - 2.5e-17 62.9 0.0 5.7e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC2_membrane PF01061.19 CEP08795.1 - 3.9e-88 294.0 50.9 3.3e-48 163.6 12.9 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 CEP08795.1 - 1.9e-36 125.3 0.0 4e-20 72.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CEP08795.1 - 9.6e-31 105.5 6.9 4.2e-23 80.9 0.1 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CEP08795.1 - 2.6e-09 37.0 0.1 7.7e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CEP08795.1 - 1.3e-06 27.7 61.3 0.00018 20.6 11.5 4.1 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 CEP08795.1 - 5.5e-06 26.5 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CEP08795.1 - 0.0001 21.7 0.3 0.0042 16.5 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP08795.1 - 0.00019 21.5 0.2 0.091 12.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 CEP08795.1 - 0.00024 20.5 0.2 0.077 12.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CEP08795.1 - 0.00031 19.9 0.1 0.0039 16.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CEP08795.1 - 0.0011 18.9 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 CEP08795.1 - 0.0017 18.0 1.2 0.15 11.6 0.2 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 CEP08795.1 - 0.0036 16.7 0.3 1.2 8.5 0.1 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 CEP08795.1 - 0.0049 16.7 0.3 0.4 10.5 0.1 3.3 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CEP08795.1 - 0.006 16.8 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEP08795.1 - 0.011 15.2 0.7 0.011 15.2 0.5 3.0 3 0 0 3 3 2 0 P-loop containing region of AAA domain Miro PF08477.8 CEP08795.1 - 0.024 15.1 0.0 3.2 8.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 CEP08795.1 - 0.025 15.4 0.0 0.36 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CEP08795.1 - 0.068 13.0 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 CEP08795.1 - 0.088 12.7 1.2 0.54 10.2 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CEP08795.1 - 0.1 12.8 0.4 16 5.6 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CEP08795.1 - 0.11 12.1 0.5 3.9 7.1 0.0 2.6 3 0 0 3 3 3 0 Archaeal ATPase NACHT PF05729.7 CEP08795.1 - 0.17 11.5 0.2 3.8 7.1 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 CEP08795.1 - 0.17 11.8 0.2 19 5.2 0.1 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.1 CEP08795.1 - 0.24 10.4 0.0 1.7 7.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 CEP08795.1 - 0.53 10.5 2.4 0.49 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain UcrQ PF02939.11 CEP08796.1 - 5.7e-29 99.7 0.3 7.1e-29 99.4 0.2 1.0 1 0 0 1 1 1 1 UcrQ family zf-RING_4 PF14570.1 CEP08797.1 - 2e-22 78.5 12.3 4e-22 77.5 8.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CEP08797.1 - 2.4e-06 27.0 7.9 2.4e-06 27.0 5.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 CEP08797.1 - 1.8e-05 24.5 0.0 4.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP08797.1 - 0.00012 21.5 0.0 0.00038 20.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CEP08797.1 - 0.0015 18.5 12.1 0.0034 17.3 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ROS_MUCR PF05443.6 CEP08797.1 - 0.016 15.0 0.5 0.055 13.2 0.0 2.2 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-UDP PF14569.1 CEP08797.1 - 0.023 14.4 3.7 0.084 12.6 2.5 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 CEP08797.1 - 0.038 13.7 2.9 0.078 12.7 2.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 CEP08797.1 - 0.049 13.2 11.1 0.12 12.0 7.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.1 CEP08797.1 - 0.17 11.7 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Rtf2 PF04641.7 CEP08797.1 - 0.51 9.4 13.5 0.13 11.4 1.5 2.9 3 0 0 3 3 3 0 Rtf2 RING-finger ABC2_membrane PF01061.19 CEP08798.1 - 1.2e-86 289.2 74.1 6.7e-49 165.9 16.3 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 CEP08798.1 - 3e-34 118.2 0.2 6e-18 65.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 CEP08798.1 - 1.8e-24 85.3 1.2 3.2e-18 65.3 0.0 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 CEP08798.1 - 1.1e-09 38.2 0.1 2.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 CEP08798.1 - 2.9e-05 24.1 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEP08798.1 - 0.00021 20.5 0.0 0.0061 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 CEP08798.1 - 0.00028 20.7 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 CEP08798.1 - 0.00043 19.4 27.3 0.00043 19.4 18.9 3.9 2 2 2 4 4 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 CEP08798.1 - 0.00045 19.6 0.1 0.0045 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP08798.1 - 0.0012 18.9 1.0 0.3 11.2 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.1 CEP08798.1 - 0.002 17.6 0.6 0.0091 15.5 0.2 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 CEP08798.1 - 0.0049 16.4 1.1 1.1 8.8 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 CEP08798.1 - 0.0082 15.5 0.1 0.046 13.1 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CEP08798.1 - 0.015 15.6 0.3 0.19 12.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.1 CEP08798.1 - 0.032 15.0 0.0 0.76 10.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CEP08798.1 - 0.052 13.7 0.0 21 5.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEP08798.1 - 0.069 13.1 0.1 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 CEP08798.1 - 0.083 12.8 0.1 0.54 10.2 0.0 2.4 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CEP08798.1 - 0.099 12.9 0.5 0.74 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CEP08798.1 - 0.1 12.3 0.5 13 5.4 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase AAA_28 PF13521.1 CEP08798.1 - 0.1 12.5 0.2 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP08798.1 - 0.11 12.0 0.5 2.1 7.9 0.1 2.7 2 1 1 3 3 3 0 NACHT domain AAA_19 PF13245.1 CEP08798.1 - 0.15 11.8 1.8 4 7.2 0.2 2.4 2 0 0 2 2 2 0 Part of AAA domain DnaJ PF00226.26 CEP08799.1 - 1.2e-20 72.9 4.5 2.3e-20 72.1 3.1 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosom_S12_S23 PF00164.20 CEP08800.1 - 8.2e-41 138.2 0.8 9.6e-41 138.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RVT_1 PF00078.22 CEP08801.1 - 4.4e-21 75.2 0.1 1.6e-20 73.3 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP08801.1 - 3.5e-19 69.0 1.1 2e-18 66.6 0.0 2.9 4 0 0 4 4 4 1 Integrase core domain Asp_protease_2 PF13650.1 CEP08801.1 - 3.2e-09 37.1 0.0 2.1e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.18 CEP08801.1 - 6.3e-06 25.8 2.8 1.2e-05 24.9 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 CEP08801.1 - 8.7e-06 25.7 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CEP08801.1 - 0.00042 19.8 0.1 0.0014 18.2 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP08801.1 - 0.0014 18.5 0.1 0.0049 16.7 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP08801.1 - 0.0029 17.3 0.0 0.0072 16.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.1 CEP08801.1 - 0.0092 15.4 0.0 0.032 13.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Serglycin PF04360.7 CEP08801.1 - 0.048 13.3 0.0 0.24 11.1 0.2 2.1 2 0 0 2 2 2 0 Serglycin PAPS_reduct PF01507.14 CEP08802.1 - 1e-44 152.4 0.0 1.3e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MMS19_N PF14500.1 CEP08803.1 - 4.4e-83 278.5 8.8 8.9e-83 277.5 0.6 3.6 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CEP08803.1 - 7.7e-82 275.2 37.6 9.5e-80 268.3 16.5 4.4 2 1 1 4 4 4 2 RNAPII transcription regulator C-terminal HEAT PF02985.17 CEP08803.1 - 0.00065 19.5 0.1 19 5.6 0.0 4.8 3 0 0 3 3 3 2 HEAT repeat Ipi1_N PF12333.3 CEP08803.1 - 0.0034 17.3 0.9 1.1 9.2 0.0 4.5 4 1 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 CEP08803.1 - 0.019 15.4 6.5 3.2 8.3 0.0 6.1 6 1 0 6 6 6 0 HEAT-like repeat AAA PF00004.24 CEP08804.1 - 3.2e-41 140.6 0.0 7.6e-41 139.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEP08804.1 - 1.2e-05 25.0 0.1 7.6e-05 22.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP08804.1 - 1.3e-05 25.2 1.1 0.0032 17.4 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 CEP08804.1 - 0.00012 21.1 0.0 0.00034 19.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CEP08804.1 - 0.00023 21.2 0.4 0.017 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 CEP08804.1 - 0.00026 20.9 0.0 0.002 18.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CEP08804.1 - 0.001 18.0 0.0 0.0021 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 CEP08804.1 - 0.0011 18.2 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 CEP08804.1 - 0.0021 18.8 1.5 0.0054 17.5 0.0 2.4 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CEP08804.1 - 0.0045 16.1 0.1 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CEP08804.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CEP08804.1 - 0.005 16.7 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP08804.1 - 0.0056 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CEP08804.1 - 0.0063 16.1 0.3 0.76 9.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CEP08804.1 - 0.0063 15.9 0.1 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CEP08804.1 - 0.019 14.0 0.1 0.054 12.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 CEP08804.1 - 0.026 13.9 0.8 0.42 9.9 0.1 2.5 1 1 0 2 2 2 0 AAA domain DUF1192 PF06698.6 CEP08804.1 - 0.042 13.6 2.8 0.22 11.3 2.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) AAA_24 PF13479.1 CEP08804.1 - 0.042 13.4 0.5 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CEP08804.1 - 0.048 12.7 0.2 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.21 CEP08804.1 - 0.08 12.4 0.0 0.32 10.4 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CEP08804.1 - 0.089 12.4 0.2 2 8.0 0.0 2.4 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CEP08804.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DivIC PF04977.10 CEP08804.1 - 0.71 9.3 4.2 2.4 7.7 2.9 2.0 1 0 0 1 1 1 0 Septum formation initiator MTHFR PF02219.12 CEP08805.1 - 6e-116 386.5 0.0 8e-116 386.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Phytochelatin PF05023.9 CEP08806.1 - 0.066 12.1 0.0 0.078 11.9 0.0 1.0 1 0 0 1 1 1 0 Phytochelatin synthase DDE_3 PF13358.1 CEP08808.1 - 5.1e-30 104.1 0.0 8.8e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP08808.1 - 0.00028 20.8 0.4 0.00081 19.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP08808.1 - 0.0003 21.5 0.0 0.00084 20.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 CEP08808.1 - 0.001 18.6 0.1 0.0033 17.0 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_psq PF05225.11 CEP08808.1 - 0.0021 17.5 0.0 0.0056 16.2 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 CEP08808.1 - 0.0022 17.2 0.2 0.02 14.0 0.1 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF1804 PF08822.6 CEP08808.1 - 0.0029 17.3 0.1 0.023 14.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1804) HTH_29 PF13551.1 CEP08808.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 CEP08808.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_7 PF02796.10 CEP08808.1 - 0.079 12.8 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase zf-C2H2_2 PF12756.2 CEP08809.1 - 9.3e-17 61.0 63.1 0.00012 22.1 0.2 10.9 4 2 9 13 13 13 11 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CEP08809.1 - 1.8e-15 56.5 92.4 0.0047 17.0 2.1 14.1 14 0 0 14 14 14 12 Zinc-finger of C2H2 type CENP-B_dimeris PF09026.5 CEP08810.1 - 0.077 13.2 3.8 0.086 13.0 2.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Astro_capsid PF03115.9 CEP08810.1 - 0.28 9.3 4.9 0.26 9.5 3.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1688 PF07958.6 CEP08811.1 - 9.6e-121 403.2 0.0 1.2e-120 402.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) zf-CCCH PF00642.19 CEP08812.1 - 0.00058 19.4 1.0 0.0011 18.6 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CEP08812.1 - 0.038 13.9 2.6 0.076 13.0 1.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Phage_DNA_bind PF02303.12 CEP08813.1 - 0.00097 19.1 0.1 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Helix-destabilising protein EphA2_TM PF14575.1 CEP08815.1 - 5.8 7.3 0.0 5.8 7.3 0.0 3.3 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain p450 PF00067.17 CEP08816.1 - 4.7e-82 275.9 0.0 6.4e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4255 PF14065.1 CEP08816.1 - 0.028 13.8 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) F-box-like PF12937.2 CEP08817.1 - 0.00034 20.2 0.0 0.00082 19.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP08817.1 - 0.017 14.7 0.0 0.064 12.9 0.0 2.0 2 0 0 2 2 2 0 F-box domain DUF4162 PF13732.1 CEP08818.1 - 0.015 15.7 0.2 14 6.2 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) DUF4268 PF14088.1 CEP08818.1 - 0.095 12.3 0.7 12 5.5 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4268) Pkinase PF00069.20 CEP08819.1 - 1.2e-55 188.4 0.1 1.2e-55 188.4 0.1 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08819.1 - 2.4e-40 138.2 0.0 5.1e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Tropomyosin_1 PF12718.2 CEP08819.1 - 0.026 14.3 15.6 0.052 13.4 10.8 1.5 1 0 0 1 1 1 0 Tropomyosin like POR PF01558.13 CEP08819.1 - 0.048 13.5 0.1 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Ferric_reduct PF01794.14 CEP08820.1 - 1.1e-16 61.0 5.6 2.3e-16 60.0 3.9 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CEP08820.1 - 8.2e-12 45.2 0.0 2.9e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CEP08820.1 - 1.4e-11 44.1 0.1 3.1e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 CEP08820.1 - 0.00011 22.7 0.0 0.00041 20.8 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEP08820.1 - 0.004 17.2 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain zf-CCHC PF00098.18 CEP08823.1 - 0.024 14.5 0.3 0.036 14.0 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle PLDc_2 PF13091.1 CEP08824.1 - 3.6e-27 94.6 0.2 5.8e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 PLD-like domain DUF1669 PF07894.7 CEP08824.1 - 7.9e-06 25.2 3.9 0.028 13.5 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1669) PLDc PF00614.17 CEP08824.1 - 0.082 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Phospholipase D Active site motif Ribosomal_60s PF00428.14 CEP08824.1 - 0.21 11.9 6.1 0.27 11.6 1.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3408 PF11888.3 CEP08824.1 - 2.8 7.8 6.0 0.67 9.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Umbravirus_LDM PF04817.7 CEP08824.1 - 7.7 5.5 7.9 7.4 5.6 1.0 2.2 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family Phage_holin_1 PF04531.8 CEP08825.1 - 2.4 8.2 4.6 15 5.7 0.6 2.7 2 1 1 3 3 3 0 Bacteriophage holin HLH PF00010.21 CEP08827.1 - 1.1e-19 69.7 0.4 1.1e-19 69.7 0.3 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2591 PF10765.4 CEP08829.1 - 0.015 15.5 0.1 0.019 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2591) DUF4231 PF14015.1 CEP08831.1 - 0.14 12.1 0.3 0.14 12.1 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Septin PF00735.13 CEP08832.1 - 1.6e-111 371.8 1.0 2e-111 371.5 0.7 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEP08832.1 - 1.8e-09 37.5 0.1 4e-09 36.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP08832.1 - 2.6e-07 29.9 0.2 4.2e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CEP08832.1 - 1.1e-06 27.9 0.1 2.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 CEP08832.1 - 2.5e-05 23.8 0.2 0.00031 20.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 CEP08832.1 - 4.4e-05 23.0 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain Dynamin_N PF00350.18 CEP08832.1 - 0.0001 22.1 1.4 0.12 12.1 0.2 2.7 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 CEP08832.1 - 0.00071 19.1 0.1 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 CEP08832.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CEP08832.1 - 0.0019 18.4 0.8 0.0039 17.4 0.5 1.7 1 1 0 1 1 1 1 ABC transporter Ras PF00071.17 CEP08832.1 - 0.0035 16.7 0.1 0.0083 15.5 0.1 1.6 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.1 CEP08832.1 - 0.0037 17.2 0.1 0.027 14.4 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain Miro PF08477.8 CEP08832.1 - 0.005 17.3 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein T2SE PF00437.15 CEP08832.1 - 0.0062 15.4 0.3 0.014 14.2 0.2 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.8 CEP08832.1 - 0.01 14.7 0.2 0.032 13.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CEP08832.1 - 0.013 15.3 0.1 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CEP08832.1 - 0.014 16.2 0.3 2 9.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 CEP08832.1 - 0.018 15.1 0.0 0.049 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 CEP08832.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_7 PF12775.2 CEP08832.1 - 0.023 13.7 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 IIGP PF05049.8 CEP08832.1 - 0.029 13.1 0.1 0.063 12.0 0.1 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 CEP08832.1 - 0.033 13.7 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 CEP08832.1 - 0.044 13.2 0.4 0.24 10.8 0.2 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF1542 PF07564.6 CEP08832.1 - 0.048 13.6 0.4 0.15 12.0 0.0 2.0 2 0 0 2 2 1 0 Domain of Unknown Function (DUF1542) NB-ARC PF00931.17 CEP08832.1 - 0.065 12.0 1.0 0.12 11.1 0.2 1.7 1 1 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 CEP08832.1 - 0.078 12.4 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 CEP08832.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CEP08832.1 - 0.15 11.9 0.5 0.6 9.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 CEP08833.1 - 4.3e-65 219.0 14.5 1.1e-64 217.7 10.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CEP08833.1 - 1.7e-27 95.7 0.0 6.3e-27 93.9 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CEP08833.1 - 3.2e-13 50.2 6.7 3.9e-07 30.3 0.6 3.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CEP08833.1 - 5.5e-08 32.2 0.0 1.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 CEP08833.1 - 1.1e-05 25.0 13.2 1.1e-05 25.0 9.1 6.2 3 2 2 6 6 5 1 IncA protein SbcCD_C PF13558.1 CEP08833.1 - 0.0054 16.6 0.0 0.021 14.7 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit CENP-F_leu_zip PF10473.4 CEP08833.1 - 0.0074 16.1 3.9 0.0074 16.1 2.7 8.2 6 3 2 8 8 7 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_23 PF13476.1 CEP08833.1 - 0.014 15.7 102.2 0.69 10.2 39.0 6.4 3 2 0 3 3 2 0 AAA domain ABC_tran PF00005.22 CEP08833.1 - 0.065 13.5 0.0 0.095 12.9 0.0 5.6 4 3 0 4 4 3 0 ABC transporter DASH_Dam1 PF08653.5 CEP08833.1 - 1.9 8.2 8.1 6.1 6.6 0.0 4.9 4 1 1 5 5 5 0 DASH complex subunit Dam1 Reo_sigmaC PF04582.7 CEP08833.1 - 4.4 6.3 27.3 0.38 9.9 0.2 5.2 5 1 1 6 6 6 0 Reovirus sigma C capsid protein zf-ZPR1 PF03367.8 CEP08834.1 - 1.8e-110 365.3 0.4 8.4e-55 184.3 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-ribbon_3 PF13248.1 CEP08834.1 - 0.006 15.7 11.1 0.096 11.9 1.7 3.6 3 1 0 3 3 3 2 zinc-ribbon domain DZR PF12773.2 CEP08834.1 - 0.038 13.7 6.9 2.9 7.7 1.5 3.6 3 1 0 3 3 3 0 Double zinc ribbon UPF0547 PF10571.4 CEP08834.1 - 0.25 11.0 10.6 0.84 9.3 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 CEP08834.1 - 1.3 8.6 16.0 6.7 6.3 0.7 4.5 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.17 CEP08834.1 - 3 7.6 5.9 4.6 7.0 1.0 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 CEP08835.1 - 5.8e-18 64.9 0.4 1e-17 64.1 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08835.1 - 0.00026 20.1 0.1 0.0004 19.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Csm1 PF12539.3 CEP08835.1 - 0.029 14.8 2.3 0.11 12.9 0.0 2.9 3 0 0 3 3 3 0 Chromosome segregation protein Csm1/Pcs1 Syndecan PF01034.15 CEP08835.1 - 0.12 11.9 0.3 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain VSP PF03302.8 CEP08835.1 - 4.8 5.7 3.7 7.5 5.0 2.6 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein UCH PF00443.24 CEP08837.1 - 2.2e-55 187.6 0.6 3.2e-55 187.1 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP08837.1 - 1.1e-29 103.8 0.0 1.6e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CEP08837.1 - 6.8e-11 42.4 0.4 2.8e-10 40.4 0.1 2.3 2 1 0 2 2 2 1 MATH domain RTC4 PF14474.1 CEP08838.1 - 2.7e-18 66.1 0.1 5.7e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 RTC4-like domain DDE_Tnp_1_2 PF13586.1 CEP08838.1 - 0.23 11.6 1.4 0.44 10.7 0.0 2.2 3 0 0 3 3 3 0 Transposase DDE domain MIF4G_like PF09088.6 CEP08839.1 - 2.6e-58 196.6 0.5 5.2e-58 195.6 0.1 1.7 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 CEP08839.1 - 4.4e-50 170.2 8.7 8.9e-50 169.2 6.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 CEP08839.1 - 5e-14 52.2 0.2 5e-13 48.9 0.1 2.5 2 0 0 2 2 2 1 MIF4G domain HAUS6_N PF14661.1 CEP08840.1 - 1.6e-10 40.7 2.3 2.5e-10 40.1 1.6 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus zf-CCCH_2 PF14608.1 CEP08841.1 - 6.1e-12 45.0 25.0 0.00033 20.5 0.1 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type Mt_ATP-synt_B PF05405.9 CEP08841.1 - 0.1 12.0 0.1 0.1 12.0 0.1 2.7 3 1 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ras PF00071.17 CEP08842.1 - 2.3e-61 205.9 0.1 2.8e-61 205.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP08842.1 - 7.1e-22 78.1 0.0 1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP08842.1 - 3.4e-13 49.2 0.0 4.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEP08842.1 - 7.2e-07 29.1 0.1 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CEP08842.1 - 3.7e-06 27.1 0.0 1.2e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 CEP08842.1 - 0.00018 21.0 0.1 0.00064 19.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP08842.1 - 0.00024 20.3 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 CEP08842.1 - 0.00094 18.3 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 CEP08842.1 - 0.0011 18.2 0.0 0.0017 17.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CEP08842.1 - 0.0023 17.1 0.0 0.0054 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 CEP08842.1 - 0.0025 17.6 0.0 0.0049 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CEP08842.1 - 0.0057 16.2 0.1 0.013 15.0 0.1 1.7 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 CEP08842.1 - 0.018 15.3 0.0 0.023 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 CEP08842.1 - 0.02 14.3 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 CEP08842.1 - 0.023 13.9 0.2 0.078 12.2 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_32 PF13654.1 CEP08842.1 - 0.025 13.2 0.0 0.25 9.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.4 CEP08842.1 - 0.028 13.8 0.0 0.07 12.6 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 CEP08842.1 - 0.035 13.2 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 CEP08842.1 - 0.054 13.4 0.2 0.097 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 CEP08842.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CEP08842.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SpoIIID PF12116.3 CEP08842.1 - 0.13 12.2 0.0 3.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D Pex24p PF06398.6 CEP08843.1 - 1.1e-24 86.9 15.7 1.6e-24 86.4 10.9 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Nucleoside_tran PF01733.13 CEP08844.1 - 7.7e-18 64.6 13.5 7.7e-18 64.6 9.3 2.8 2 1 1 3 3 3 1 Nucleoside transporter DUF912 PF06024.7 CEP08844.1 - 0.098 12.7 0.0 0.36 10.8 0.0 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BRI3BP PF14965.1 CEP08844.1 - 5.7 6.2 9.5 6 6.2 0.9 3.0 3 1 1 4 4 4 0 Negative regulator of p53/TP53 HTH_psq PF05225.11 CEP08845.1 - 4.8e-07 29.2 0.0 1.6e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP08845.1 - 4.9e-06 26.4 0.9 1.1e-05 25.2 0.6 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP08845.1 - 5.8e-05 23.2 0.1 0.00012 22.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP08845.1 - 0.00011 22.9 0.3 0.00099 19.8 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.8 CEP08845.1 - 0.00015 21.0 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DDE_3 PF13358.1 CEP08845.1 - 0.00034 20.3 0.0 0.00065 19.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP08845.1 - 0.0031 17.1 0.1 0.01 15.4 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain FeoC PF09012.5 CEP08845.1 - 0.0037 16.9 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_3 PF01381.17 CEP08845.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_24 PF13412.1 CEP08845.1 - 0.061 12.7 0.1 0.26 10.7 0.1 2.2 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 CEP08845.1 - 0.063 13.5 0.2 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 CEP08845.1 - 0.068 12.3 0.0 0.18 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Mab-21 PF03281.9 CEP08847.1 - 0.0048 16.0 1.0 0.0077 15.4 0.4 1.5 1 1 0 1 1 1 1 Mab-21 protein Snapin_Pallidin PF14712.1 CEP08847.1 - 0.016 15.5 0.6 0.039 14.2 0.4 1.6 1 0 0 1 1 1 0 Snapin/Pallidin DUF4101 PF13355.1 CEP08847.1 - 0.039 14.3 1.7 0.085 13.2 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) NDT80_PhoG PF05224.7 CEP08848.1 - 3.1e-35 121.8 2.3 4e-35 121.5 0.1 2.4 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family RRM_6 PF14259.1 CEP08849.1 - 1.1e-12 47.7 0.0 2.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP08849.1 - 2.1e-08 33.6 0.0 6.7e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CEP08849.1 - 0.00018 21.0 13.0 0.019 14.6 7.4 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 CEP08849.1 - 0.00029 20.6 0.1 0.00092 19.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CEP08849.1 - 3.5 7.7 18.9 34 4.5 8.6 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP08849.1 - 6.6 6.4 16.8 0.7 9.6 7.9 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PNP_UDP_1 PF01048.15 CEP08850.1 - 8.9e-39 132.8 0.0 1e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Acetyltransf_1 PF00583.19 CEP08851.1 - 3.5e-08 33.3 0.1 5.3e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP08851.1 - 9.1e-08 32.1 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP08851.1 - 1.3e-05 25.0 0.0 1.9e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP08851.1 - 7.3e-05 22.8 0.0 8.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4085 PF13315.1 CEP08851.1 - 0.04 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUP PF00674.13 CEP08851.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 DUP family Thioredoxin PF00085.15 CEP08852.1 - 3.8e-31 106.8 0.3 4.4e-31 106.6 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CEP08852.1 - 8.7e-08 32.3 0.2 7.6e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEP08852.1 - 1.9e-07 31.0 0.1 4.3e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CEP08852.1 - 5.4e-05 23.1 0.2 0.0001 22.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CEP08852.1 - 0.0004 20.0 0.1 0.0006 19.4 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 CEP08852.1 - 0.00074 19.0 0.0 0.00085 18.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 CEP08852.1 - 0.0025 17.3 0.0 0.0029 17.1 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.6 CEP08852.1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 CEP08852.1 - 0.012 15.1 0.3 0.019 14.5 0.2 1.4 1 1 0 1 1 1 0 Redoxin Phosducin PF02114.11 CEP08852.1 - 0.033 12.8 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_6 PF13848.1 CEP08852.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.5 1 1 1 2 2 2 0 Thioredoxin-like domain SAP PF02037.22 CEP08853.1 - 2e-09 36.6 0.3 3.4e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 SAP domain Syntaxin PF00804.20 CEP08854.1 - 3.5e-16 59.2 6.0 3.5e-16 59.2 4.1 2.9 3 1 0 3 3 3 1 Syntaxin SNARE PF05739.14 CEP08854.1 - 6.5e-14 51.3 2.5 6.5e-14 51.3 1.7 3.2 3 1 1 4 4 4 1 SNARE domain zf-C4H2 PF10146.4 CEP08854.1 - 0.0045 17.0 13.7 0.69 9.8 5.9 2.3 1 1 1 2 2 2 2 Zinc finger-containing protein Peripla_BP_2 PF01497.13 CEP08854.1 - 0.022 13.8 0.5 0.022 13.8 0.3 1.9 2 0 0 2 2 2 0 Periplasmic binding protein Syntaxin-18_N PF10496.4 CEP08854.1 - 0.046 13.5 0.5 0.046 13.5 0.4 2.9 2 1 1 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Romo1 PF10247.4 CEP08854.1 - 0.21 11.7 2.5 0.45 10.7 1.7 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Syntaxin-6_N PF09177.6 CEP08854.1 - 0.48 10.8 9.7 0.57 10.6 0.9 3.4 3 1 0 3 3 3 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 CEP08854.1 - 2.4 8.0 6.4 0.6 10.0 0.3 3.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 CEP08854.1 - 2.7 7.8 12.0 3.8 7.3 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 CEP08854.1 - 4.1 7.7 10.0 18 5.6 0.6 3.7 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.16 CEP08854.1 - 5 6.6 15.8 0.091 12.2 2.2 2.8 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UCH PF00443.24 CEP08855.1 - 7.6e-43 146.5 14.3 1e-41 142.8 9.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CEP08855.1 - 5.1e-11 41.8 1.3 1.4e-06 27.6 0.0 3.0 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.1 CEP08855.1 - 1.7e-09 37.5 7.8 9.4e-08 31.8 5.4 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 CEP08855.1 - 0.0066 16.1 0.2 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 PUB domain Tnp_zf-ribbon_2 PF13842.1 CEP08855.1 - 0.064 13.6 1.0 0.13 12.7 0.3 1.8 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Cu_amine_oxid PF01179.15 CEP08856.1 - 2e-25 89.4 1.6 2.4e-25 89.1 1.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain FAD_binding_1 PF00667.15 CEP08857.1 - 5.1e-56 189.5 0.1 8.2e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CEP08857.1 - 1.1e-34 119.5 1.3 1.8e-34 118.7 0.3 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 CEP08857.1 - 1.3e-20 73.9 0.0 1.1e-19 71.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SOG2 PF10428.4 CEP08858.1 - 9.7e-32 110.1 20.9 2.7e-22 79.0 0.7 2.9 1 1 2 3 3 3 2 RAM signalling pathway protein Oxidored-like PF09791.4 CEP08858.1 - 6e-11 41.6 0.8 1.3e-10 40.5 0.6 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal WW PF00397.21 CEP08859.1 - 2.8e-05 23.8 0.2 2.8e-05 23.8 0.1 2.8 3 0 0 3 3 3 1 WW domain Na_H_Exchanger PF00999.16 CEP08860.1 - 3.1e-46 157.6 27.5 4.3e-46 157.1 19.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.3 CEP08860.1 - 0.75 9.4 5.1 0.22 11.1 0.2 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.20 CEP08861.1 - 2.7e-39 134.9 0.5 2.8e-38 131.5 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08861.1 - 1.1e-13 50.8 0.5 1.2e-11 44.1 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CEP08861.1 - 0.0097 15.6 0.0 0.049 13.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RAP1 PF07218.6 CEP08861.1 - 0.037 12.1 5.5 0.056 11.5 3.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3708 PF12501.3 CEP08861.1 - 0.12 12.1 1.9 0.24 11.2 1.3 1.4 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF763 PF05559.6 CEP08861.1 - 3 6.7 6.6 4.8 6.0 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Exo_endo_phos PF03372.18 CEP08862.1 - 1.5e-17 64.3 1.2 3.4e-17 63.2 0.8 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PIF1 PF05970.9 CEP08864.1 - 1.4e-13 50.5 0.0 1.6e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase DUF1376 PF07120.6 CEP08864.1 - 0.074 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) DUF2151 PF10221.4 CEP08865.1 - 0.074 11.2 0.9 0.08 11.1 0.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator ISN1 PF06437.6 CEP08865.1 - 0.075 11.7 1.8 0.1 11.2 1.2 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Hid1 PF12722.2 CEP08867.1 - 8 3.9 12.2 11 3.5 8.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIF1 PF05970.9 CEP08869.1 - 2.8e-13 49.5 0.1 3e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 CEP08870.1 - 4.9e-43 147.4 0.0 5.5e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP08870.1 - 6e-08 32.4 0.0 7.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP08870.1 - 0.00039 20.1 0.2 0.00058 19.5 0.1 1.3 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CEP08870.1 - 0.0051 15.8 0.0 0.0056 15.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CEP08870.1 - 0.0094 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 CEP08870.1 - 0.012 14.2 0.0 0.022 13.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 CEP08870.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP08870.1 - 0.031 14.2 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 CEP08870.1 - 0.088 11.6 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1604 PF07713.8 CEP08872.1 - 1.5 8.6 9.0 0.64 9.8 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1604) zf-CCHC PF00098.18 CEP08873.1 - 1.7e-05 24.5 3.4 2.5e-05 23.9 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CEP08873.1 - 0.0011 18.6 1.1 0.0011 18.6 0.7 1.6 2 0 0 2 2 2 1 Zinc knuckle DUF3725 PF12523.3 CEP08873.1 - 0.025 14.6 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) DUF4596 PF15363.1 CEP08873.1 - 0.053 13.4 0.4 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) zf-CCHC_4 PF14392.1 CEP08873.1 - 0.12 12.0 1.7 0.23 11.1 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 CEP08875.1 - 3.5e-34 118.0 0.0 7.7e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP08875.1 - 7.7e-05 22.9 1.3 0.00022 21.4 0.9 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Retrotrans_gag PF03732.12 CEP08876.1 - 4.3e-06 26.7 1.8 8.9e-06 25.6 0.3 2.2 2 2 0 2 2 2 1 Retrotransposon gag protein TerB PF05099.8 CEP08876.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TerB UBN2 PF14223.1 CEP08876.1 - 0.0067 16.2 0.8 0.096 12.4 0.1 2.6 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CEP08876.1 - 0.013 15.0 0.1 0.032 13.7 0.1 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type FlaC_arch PF05377.6 CEP08876.1 - 0.099 12.5 0.1 5 7.1 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BNIP3 PF06553.7 CEP08877.1 - 0.0071 15.7 8.0 0.016 14.5 5.5 1.6 1 1 0 1 1 1 1 BNIP3 Mito_fiss_reg PF05308.6 CEP08877.1 - 0.037 13.3 12.3 0.055 12.8 8.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator EPL1 PF10513.4 CEP08877.1 - 0.11 12.6 7.8 0.16 12.1 5.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Presenilin PF01080.12 CEP08877.1 - 0.18 10.5 8.5 0.24 10.1 5.9 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.4 CEP08877.1 - 0.26 9.4 16.5 0.29 9.3 11.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec10 PF07393.6 CEP08877.1 - 0.65 8.1 7.9 0.78 7.8 5.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Lin-8 PF03353.10 CEP08877.1 - 0.7 9.1 10.8 1 8.5 7.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MRP-S25 PF13741.1 CEP08877.1 - 1.3 8.4 12.7 1.7 8.0 8.4 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S25 Suf PF05843.9 CEP08877.1 - 1.9 8.1 12.0 2.5 7.7 8.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 CEP08877.1 - 2.5 6.3 9.3 2.8 6.2 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.8 CEP08877.1 - 6.7 6.1 12.0 9.3 5.6 8.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FLO_LFY PF01698.11 CEP08877.1 - 7.9 5.2 10.0 11 4.7 6.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Rootletin PF15035.1 CEP08878.1 - 0.037 13.9 1.4 0.041 13.8 1.0 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4120 PF13496.1 CEP08878.1 - 0.063 13.3 0.1 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) TMEM247 PF15444.1 CEP08878.1 - 0.39 10.5 3.8 8.1 6.1 2.6 2.1 1 1 0 1 1 1 0 Transmembrane protein 247 AOX PF01786.12 CEP08879.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alternative oxidase RVT_1 PF00078.22 CEP08880.1 - 0.0011 18.3 0.1 0.002 17.4 0.1 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH_3 PF14593.1 CEP08880.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 PH domain GCR1_C PF12550.3 CEP08881.1 - 2.4e-21 75.3 3.6 8e-21 73.7 2.5 2.0 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_5 PF08360.6 CEP08881.1 - 0.01 15.8 2.4 0.014 15.3 0.6 2.1 2 0 0 2 2 2 1 QacR-like protein, C-terminal region C2 PF00168.25 CEP08882.1 - 5.8e-19 67.7 0.1 1.9e-18 66.0 0.0 2.0 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 CEP08882.1 - 4.4e-12 45.9 3.0 7.4e-12 45.2 0.9 2.4 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.6 CEP08882.1 - 3.1e-06 25.7 9.5 0.0019 16.5 0.1 3.8 4 1 0 4 4 4 3 Protein of unknown function (DUF810) HSP70 PF00012.15 CEP08883.1 - 2.8e-07 28.8 0.0 3.4e-05 21.9 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CEP08883.1 - 0.35 9.4 0.0 1.1 7.8 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.20 CEP08884.1 - 6.3e-73 245.1 0.1 1e-72 244.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08884.1 - 2.1e-35 122.0 0.0 4.9e-35 120.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CEP08884.1 - 1.5e-19 69.1 0.1 3e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 CEP08884.1 - 4.4e-06 25.8 0.0 9e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP08884.1 - 0.00025 20.1 0.0 0.0007 18.7 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP08884.1 - 0.00063 19.5 0.0 0.013 15.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Hemagglutinin PF00509.13 CEP08884.1 - 0.005 15.0 0.4 1.9 6.4 0.0 2.2 2 0 0 2 2 2 2 Haemagglutinin YrbL-PhoP_reg PF10707.4 CEP08884.1 - 0.068 12.4 0.8 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Lipase_GDSL PF00657.17 CEP08885.1 - 2e-14 54.0 0.0 3.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP08885.1 - 1.9e-06 28.1 0.0 3.9e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Retrotrans_gag PF03732.12 CEP08887.1 - 9.5e-15 54.4 0.0 1.3e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein HTH_30 PF13556.1 CEP08888.1 - 0.058 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain RVT_1 PF00078.22 CEP08889.1 - 4e-22 78.6 0.2 1.1e-21 77.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 CEP08889.1 - 0.00053 19.4 0.2 0.0013 18.1 0.1 1.7 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RVT_3 PF13456.1 CEP08889.1 - 0.016 14.9 0.1 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Ipi1_N PF12333.3 CEP08889.1 - 0.038 13.9 1.5 0.097 12.6 0.1 2.2 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation FlxA PF14282.1 CEP08890.1 - 0.08 12.9 1.3 0.1 12.5 0.9 1.2 1 0 0 1 1 1 0 FlxA-like protein PAP1 PF08601.5 CEP08891.1 - 0.18 11.4 2.1 0.2 11.2 1.5 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Retrotrans_gag PF03732.12 CEP08893.1 - 2.5e-05 24.2 0.1 0.01 15.8 0.0 2.2 1 1 1 2 2 2 2 Retrotransposon gag protein PNMA PF14893.1 CEP08893.1 - 0.005 15.8 0.0 0.0055 15.7 0.0 1.1 1 0 0 1 1 1 1 PNMA Sgf11 PF08209.6 CEP08895.1 - 0.018 14.3 2.5 0.84 9.0 0.3 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn_Tnp_IS1595 PF12760.2 CEP08895.1 - 0.038 13.7 5.9 1.6 8.5 0.7 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ADK_lid PF05191.9 CEP08895.1 - 0.12 12.0 4.0 0.4 10.3 0.0 3.3 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-CHY PF05495.7 CEP08895.1 - 2.3 8.4 9.8 20 5.4 0.5 3.3 2 1 1 3 3 3 0 CHY zinc finger Zn_Tnp_IS1 PF03811.8 CEP08895.1 - 4.9 6.7 7.0 0.78 9.2 1.0 2.5 3 0 0 3 3 3 0 InsA N-terminal domain zf-C2HC_2 PF13913.1 CEP08895.1 - 5.4 6.8 14.6 0.35 10.6 0.7 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 CEP08895.1 - 7 7.1 6.3 7.9 6.9 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 CEP08895.1 - 7.7 6.5 6.9 16 5.5 0.1 3.4 4 0 0 4 4 4 0 Zinc ribbon domain Rootletin PF15035.1 CEP08895.1 - 8.5 6.3 16.0 22 4.9 11.1 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RVT_1 PF00078.22 CEP08896.1 - 1.3e-23 83.4 0.0 1.7e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IncA PF04156.9 CEP08898.1 - 0.00032 20.3 34.2 0.00035 20.2 18.7 2.6 1 1 1 2 2 2 1 IncA protein Leu_zip PF15294.1 CEP08898.1 - 0.00075 18.6 23.4 0.14 11.2 5.2 3.0 1 1 2 3 3 3 2 Leucine zipper bZIP_1 PF00170.16 CEP08898.1 - 0.00084 19.2 17.3 0.15 12.0 0.5 4.1 3 1 1 4 4 4 2 bZIP transcription factor APG6 PF04111.7 CEP08898.1 - 0.0012 17.9 18.7 0.0012 17.9 13.0 2.6 1 1 1 2 2 2 1 Autophagy protein Apg6 Tropomyosin PF00261.15 CEP08898.1 - 0.0013 17.8 15.0 0.0013 17.8 10.4 1.9 1 1 0 1 1 1 1 Tropomyosin DUF972 PF06156.8 CEP08898.1 - 0.0013 19.0 28.2 0.0089 16.3 3.7 3.5 1 1 2 3 3 3 1 Protein of unknown function (DUF972) DUF4200 PF13863.1 CEP08898.1 - 0.002 18.0 12.0 0.002 18.0 8.3 2.7 1 1 0 2 2 2 1 Domain of unknown function (DUF4200) DUF904 PF06005.7 CEP08898.1 - 0.0032 17.7 30.7 0.09 13.0 3.2 4.3 1 1 3 4 4 4 2 Protein of unknown function (DUF904) DUF869 PF05911.6 CEP08898.1 - 0.0048 15.2 21.2 0.0066 14.7 14.7 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DivIC PF04977.10 CEP08898.1 - 0.0056 16.1 18.5 0.66 9.4 1.1 4.4 2 1 2 4 4 4 2 Septum formation initiator ABC_tran_2 PF12848.2 CEP08898.1 - 0.015 15.0 0.2 0.015 15.0 0.2 2.7 2 1 0 2 2 1 0 ABC transporter ADIP PF11559.3 CEP08898.1 - 0.025 14.4 36.5 0.095 12.5 3.4 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF883 PF05957.8 CEP08898.1 - 0.026 14.9 2.7 0.026 14.9 1.9 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) PspA_IM30 PF04012.7 CEP08898.1 - 0.041 13.2 22.7 0.082 12.2 8.9 2.4 2 1 0 2 2 2 0 PspA/IM30 family DUF812 PF05667.6 CEP08898.1 - 0.05 12.1 25.0 0.1 11.0 17.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_2 PF07716.10 CEP08898.1 - 0.062 13.1 22.6 0.47 10.3 0.7 4.1 3 1 0 3 3 3 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 CEP08898.1 - 0.067 12.9 25.2 0.25 11.1 3.3 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Filament PF00038.16 CEP08898.1 - 0.11 11.9 27.3 0.33 10.3 10.6 2.9 1 1 2 3 3 3 0 Intermediate filament protein CENP-H PF05837.7 CEP08898.1 - 0.14 12.3 28.8 0.41 10.8 2.5 4.2 1 1 3 4 4 4 0 Centromere protein H (CENP-H) Reo_sigmaC PF04582.7 CEP08898.1 - 0.24 10.5 13.1 0.17 11.0 7.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 CEP08898.1 - 0.31 10.9 19.3 0.95 9.4 0.2 5.1 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.3 CEP08898.1 - 0.32 10.7 28.2 0.28 10.9 2.8 3.6 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 CEP08898.1 - 0.32 10.7 35.1 0.37 10.5 14.4 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mod_r PF07200.8 CEP08898.1 - 0.39 10.6 26.9 0.18 11.6 5.2 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.1 CEP08898.1 - 0.49 10.3 29.3 0.17 11.8 6.5 3.8 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 MscS_porin PF12795.2 CEP08898.1 - 0.52 9.5 42.3 0.52 9.5 20.7 3.3 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Herpes_BLRF2 PF05812.7 CEP08898.1 - 0.68 9.7 18.0 1.4 8.7 1.7 3.1 1 1 0 2 2 2 0 Herpesvirus BLRF2 protein Hemerythrin PF01814.18 CEP08898.1 - 0.88 9.7 6.6 9.6 6.3 0.2 2.8 1 1 2 3 3 3 0 Hemerythrin HHE cation binding domain HALZ PF02183.13 CEP08898.1 - 1 9.1 17.9 6.2 6.6 0.5 4.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper CCDC-167 PF15188.1 CEP08898.1 - 1.3 9.0 22.5 0.031 14.2 4.0 3.7 1 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF2077 PF09850.4 CEP08898.1 - 1.3 8.3 7.1 4.6 6.5 0.8 2.8 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) ERM PF00769.14 CEP08898.1 - 1.8 8.0 28.3 28 4.1 3.2 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family MHC_I PF00129.13 CEP08898.1 - 1.9 7.8 7.7 0.4 10.0 0.3 2.4 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Cep57_MT_bd PF06657.8 CEP08898.1 - 2 8.3 18.3 0.098 12.6 4.4 3.5 2 1 2 4 4 3 0 Centrosome microtubule-binding domain of Cep57 Med9 PF07544.8 CEP08898.1 - 2.1 8.1 19.1 1.8 8.3 1.0 4.3 2 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.4 CEP08898.1 - 2.3 7.0 27.8 1.9 7.3 8.2 2.3 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4164 PF13747.1 CEP08898.1 - 2.4 8.3 21.3 0.49 10.5 3.6 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4164) Mnd1 PF03962.10 CEP08898.1 - 2.4 7.7 26.5 1.2 8.7 6.8 2.9 1 1 2 3 3 3 0 Mnd1 family Shugoshin_N PF07558.6 CEP08898.1 - 2.5 7.8 21.5 6.4 6.5 2.4 4.5 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Prefoldin_2 PF01920.15 CEP08898.1 - 2.5 7.8 22.5 0.44 10.3 1.7 3.8 3 1 0 3 3 3 0 Prefoldin subunit DivIVA PF05103.8 CEP08898.1 - 2.9 7.9 25.6 1.9 8.5 3.3 3.3 1 1 1 3 3 3 0 DivIVA protein FUSC PF04632.7 CEP08898.1 - 3.1 6.1 9.0 4.7 5.5 6.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.4 CEP08898.1 - 3.4 7.5 31.0 34 4.2 3.2 3.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 CEP08898.1 - 4.8 6.8 20.9 0.74 9.4 1.4 3.8 4 0 0 4 4 3 0 Prefoldin subunit CENP-Q PF13094.1 CEP08898.1 - 5.8 6.9 36.5 5.5 6.9 5.8 3.2 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TSC22 PF01166.13 CEP08898.1 - 5.9 6.9 21.5 0.68 9.9 0.6 4.6 4 1 1 5 5 4 0 TSC-22/dip/bun family DUF848 PF05852.6 CEP08898.1 - 7.4 6.4 25.0 0.51 10.1 2.7 3.1 1 1 3 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) DDE_3 PF13358.1 CEP08900.1 - 7.7e-31 106.8 0.0 1.9e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP08900.1 - 0.0074 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Peroxin-3 PF04882.7 CEP08901.1 - 7.1e-103 344.6 1.3 9.5e-103 344.1 0.9 1.2 1 0 0 1 1 1 1 Peroxin-3 Anp1 PF03452.9 CEP08902.1 - 6.4e-45 153.3 0.8 8.9e-45 152.9 0.6 1.1 1 0 0 1 1 1 1 Anp1 SWIRM PF04433.12 CEP08903.1 - 2e-08 34.2 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 SWIRM domain Citrate_synt PF00285.16 CEP08907.1 - 0.045 12.4 0.0 0.06 12.0 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase RVT_1 PF00078.22 CEP08908.1 - 8.8e-06 25.2 0.1 1.6e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CEP08909.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein FWWh PF14922.1 CEP08909.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function UBN2 PF14223.1 CEP08909.1 - 0.091 12.5 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 CEP08910.1 - 8.5e-16 57.9 0.1 1.7e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CEP08910.1 - 1.6e-05 25.2 0.1 3.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 RNase H DNA_pol_viral_C PF00336.13 CEP08910.1 - 0.00053 19.3 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Retrotrans_gag PF03732.12 CEP08911.1 - 0.006 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zinc_ribbon_2 PF13240.1 CEP08911.1 - 0.032 13.7 0.4 0.078 12.4 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain UBN2 PF14223.1 CEP08911.1 - 0.038 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UPF0547 PF10571.4 CEP08911.1 - 0.096 12.3 1.7 0.33 10.6 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ribosomal_L32p PF01783.18 CEP08911.1 - 0.33 11.1 6.3 2.3 8.4 0.2 2.5 2 0 0 2 2 2 0 Ribosomal L32p protein family RVT_1 PF00078.22 CEP08912.1 - 9.9e-18 64.2 1.4 4e-17 62.2 0.3 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CEP08912.1 - 7.7e-11 41.9 0.0 7.7e-11 41.9 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.15 CEP08912.1 - 0.0001 22.1 0.0 0.00032 20.5 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEP08912.1 - 0.00011 22.5 0.0 0.00024 21.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CEP08912.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP08912.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF3502 PF12010.3 CEP08912.1 - 0.22 11.4 4.9 0.099 12.6 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) RNA_pol_Rpb1_5 PF04998.12 CEP08913.1 - 5e-93 311.3 0.4 8.8e-93 310.5 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CEP08913.1 - 6.5e-93 311.6 0.0 9.1e-93 311.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CEP08913.1 - 4.5e-68 228.3 0.0 1.5e-67 226.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CEP08913.1 - 1e-37 129.2 0.0 1.2e-36 125.8 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CEP08913.1 - 1.9e-31 108.0 0.1 6.3e-31 106.3 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 HTH_23 PF13384.1 CEP08916.1 - 3.4e-06 26.5 0.0 2.1e-05 24.0 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.5 CEP08916.1 - 0.0034 16.9 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_psq PF05225.11 CEP08916.1 - 0.015 14.7 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP08916.1 - 0.088 12.8 0.0 0.37 10.8 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain RRM_1 PF00076.17 CEP08917.1 - 6.2e-16 57.8 0.0 9.8e-16 57.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP08917.1 - 2.3e-12 46.7 0.0 3.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP08917.1 - 1.3e-05 24.9 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STAT_alpha PF01017.15 CEP08917.1 - 0.023 14.4 0.6 0.033 13.9 0.4 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain HrpA_pilin PF09589.5 CEP08917.1 - 0.033 14.6 2.4 0.047 14.1 1.7 1.3 1 0 0 1 1 1 0 HrpA pilus formation protein APG6 PF04111.7 CEP08917.1 - 0.094 11.7 9.5 0.11 11.4 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Rab5-bind PF09311.6 CEP08917.1 - 0.11 12.3 13.5 0.15 11.9 9.4 1.1 1 0 0 1 1 1 0 Rabaptin-like protein IncA PF04156.9 CEP08917.1 - 0.12 11.9 7.8 0.17 11.4 5.4 1.1 1 0 0 1 1 1 0 IncA protein Uds1 PF15456.1 CEP08917.1 - 0.12 12.3 7.2 0.18 11.7 5.0 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DivIC PF04977.10 CEP08917.1 - 0.12 11.8 4.6 0.22 11.0 3.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Sec62 PF03839.11 CEP08917.1 - 0.14 11.5 2.7 0.16 11.3 1.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4140 PF13600.1 CEP08917.1 - 0.82 10.1 4.2 1.8 9.0 2.9 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 CEP08917.1 - 3.8 7.8 7.1 7.1 7.0 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF3782 PF12644.2 CEP08917.1 - 5.1 6.9 6.1 8.5 6.2 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Spc24 PF08286.6 CEP08917.1 - 5.9 6.6 8.7 5.6 6.6 5.3 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 RNA_bind PF08675.6 CEP08918.1 - 0.034 14.1 0.1 0.089 12.7 0.0 1.7 2 0 0 2 2 2 0 RNA binding domain DUF2414 PF10309.4 CEP08918.1 - 0.05 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Cryptochrome_C PF12546.3 CEP08918.1 - 6.1 7.5 8.6 1.4 9.5 0.4 2.6 2 2 0 2 2 2 0 Blue/Ultraviolet sensing protein C terminal Globin PF00042.17 CEP08919.1 - 5.3e-05 23.5 0.0 0.0069 16.7 0.0 2.5 2 1 0 2 2 2 2 Globin Ras PF00071.17 CEP08920.1 - 2.3e-56 189.6 1.3 3.5e-56 189.0 0.9 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP08920.1 - 4.1e-17 62.7 0.0 8.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP08920.1 - 1.2e-14 53.9 0.2 2e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Cellulase PF00150.13 CEP08920.1 - 1.2e-10 41.0 0.0 3.7e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA_22 PF13401.1 CEP08920.1 - 0.0017 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 CEP08920.1 - 0.0018 17.4 0.8 0.0031 16.6 0.5 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP08920.1 - 0.0046 16.4 0.2 0.0098 15.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CEP08920.1 - 0.0088 15.2 0.4 0.015 14.5 0.3 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEP08920.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 CEP08920.1 - 0.071 13.4 0.6 0.37 11.0 0.1 2.4 2 1 0 2 2 2 0 ABC transporter DUF3533 PF12051.3 CEP08920.1 - 0.071 11.8 2.1 0.11 11.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_29 PF13555.1 CEP08920.1 - 0.075 12.5 0.1 0.51 9.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CEP08920.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP08920.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Sugar_tr PF00083.19 CEP08921.1 - 1.7e-89 300.4 26.8 2e-89 300.2 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP08921.1 - 2.1e-27 95.7 37.6 7.8e-26 90.6 19.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CEP08921.1 - 0.00015 21.4 0.1 0.58 9.9 0.0 3.2 2 0 0 2 2 2 2 MFS_1 like family BRCT PF00533.21 CEP08922.1 - 4.8e-28 97.1 0.2 3.4e-08 33.5 0.0 4.2 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CEP08922.1 - 3.2e-27 94.1 0.0 1.6e-12 47.0 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain Cytochrom_C PF00034.16 CEP08923.1 - 1.3e-11 45.1 0.1 2.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CEP08923.1 - 8.2e-08 32.2 3.5 5.6e-07 29.6 2.4 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CEP08923.1 - 0.021 14.2 0.3 0.29 10.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c-550 domain CCP_MauG PF03150.9 CEP08923.1 - 0.04 14.2 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase WD40 PF00400.27 CEP08924.1 - 5.4e-44 146.5 20.0 9.2e-12 44.3 0.0 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 CEP08924.1 - 3.3e-05 23.7 1.0 0.097 12.3 0.2 3.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 CEP08924.1 - 3.4e-05 23.5 0.1 6.3e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LSM PF01423.17 CEP08925.1 - 1.5e-16 59.6 1.4 2.1e-16 59.2 0.9 1.1 1 0 0 1 1 1 1 LSM domain GPI-anchored PF10342.4 CEP08926.1 - 5.4e-16 58.8 2.2 5.4e-16 58.8 1.5 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sec2p PF06428.6 CEP08927.1 - 9.1e-05 22.2 2.2 0.00023 20.9 1.5 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Op_neuropeptide PF08035.6 CEP08927.1 - 0.039 13.5 0.1 0.086 12.4 0.1 1.5 1 0 0 1 1 1 0 Opioids neuropeptide Asp-B-Hydro_N PF05279.6 CEP08928.1 - 1.4 8.7 8.9 1.5 8.6 6.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region vATP-synt_E PF01991.13 CEP08928.1 - 4.9 6.3 12.7 9.7 5.4 8.7 1.4 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Exonuc_VII_L PF02601.10 CEP08928.1 - 6.7 5.7 10.0 7.7 5.6 6.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit G-patch PF01585.18 CEP08929.1 - 3.8e-16 58.5 1.0 1.1e-15 57.1 0.7 1.9 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 CEP08929.1 - 4.5e-10 39.0 0.0 9.8e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 CEP08929.1 - 2e-06 27.5 0.0 2e-06 27.5 0.0 2.8 3 0 0 3 3 3 1 DExH-box splicing factor binding site zf-PARP PF00645.13 CEP08930.1 - 6.2e-12 45.5 1.4 6.2e-12 45.5 1.0 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGG PF10273.4 CEP08931.1 - 7.9e-28 96.3 0.1 1.4e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TLP-20 PF06088.6 CEP08931.1 - 0.03 13.9 2.5 0.04 13.5 1.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.9 CEP08931.1 - 3.2 5.6 7.8 3.8 5.4 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Rep_fac-A_3 PF08661.6 CEP08932.1 - 1.3e-19 70.0 0.0 1.5e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 P5CR_dimer PF14748.1 CEP08933.1 - 1.8e-37 127.5 0.9 4e-37 126.4 0.6 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CEP08933.1 - 6.6e-18 64.9 0.0 2e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CEP08933.1 - 3.7e-05 23.5 1.6 0.00018 21.2 0.6 2.4 1 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.19 CEP08933.1 - 0.0028 17.9 0.0 0.051 13.8 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Phosducin PF02114.11 CEP08934.1 - 4.3e-13 48.5 0.2 1.9e-12 46.5 0.1 1.8 1 1 0 1 1 1 1 Phosducin ECH PF00378.15 CEP08935.1 - 9.3e-31 106.8 0.1 1.1e-30 106.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DDE_3 PF13358.1 CEP08936.1 - 4.9e-26 91.2 0.0 8.9e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP08936.1 - 0.049 13.7 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain BUD22 PF09073.5 CEP08940.1 - 0.089 11.8 7.8 0.1 11.6 5.4 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 CEP08940.1 - 8.8 5.7 11.3 14 5.0 7.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.7 CEP08940.1 - 9.6 5.3 15.2 10 5.2 10.5 1.1 1 0 0 1 1 1 0 SDA1 Transposase_21 PF02992.9 CEP08941.1 - 0.0049 15.9 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 E3_binding PF02817.12 CEP08942.1 - 0.00075 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 e3 binding domain RRM_1 PF00076.17 CEP08943.1 - 1.1e-39 133.8 0.7 2.6e-17 62.2 0.2 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP08943.1 - 9.1e-28 96.0 0.2 2.3e-11 43.4 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP08943.1 - 3.1e-19 68.5 1.6 6.9e-07 29.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CEP08943.1 - 7.7e-09 35.1 0.7 0.042 13.6 0.0 5.0 5 0 0 5 5 5 2 Limkain b1 PABP PF00658.13 CEP08943.1 - 3.5e-06 26.5 0.0 3.5e-06 26.5 0.0 3.6 3 1 0 3 3 3 2 Poly-adenylate binding protein, unique domain Pkinase PF00069.20 CEP08944.1 - 7.6e-42 143.2 0.0 1.2e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08944.1 - 6.6e-24 84.3 0.0 9.7e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 CEP08944.1 - 4.5e-14 52.2 0.7 4.5e-14 52.2 0.5 2.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 CEP08944.1 - 0.028 13.3 0.0 0.083 11.8 0.0 1.8 1 1 0 1 1 1 0 Kinase-like NPBW PF15180.1 CEP08945.1 - 0.03 13.9 0.1 0.03 13.9 0.1 2.5 3 0 0 3 3 3 0 Neuropeptides B and W SR-25 PF10500.4 CEP08945.1 - 0.43 10.0 16.7 0.66 9.4 3.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.9 CEP08945.1 - 7.3 6.2 10.7 0.27 10.9 2.5 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Mito_carr PF00153.22 CEP08946.1 - 1.1e-47 159.6 4.1 4.5e-16 58.3 0.0 4.3 2 1 1 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 CEP08946.1 - 2.4e-43 148.1 0.0 1.2e-31 109.7 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP08946.1 - 1.6e-26 92.9 0.0 2.3e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP08946.1 - 0.00041 19.4 0.0 0.0018 17.2 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CEP08946.1 - 0.014 15.1 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L14 PF00238.14 CEP08947.1 - 8.4e-35 119.1 0.0 9.2e-35 119.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Oxysterol_BP PF01237.13 CEP08948.1 - 8e-80 267.9 0.1 1.2e-79 267.3 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Sel1 PF08238.7 CEP08949.1 - 2.6e-110 358.4 103.1 2.1e-06 28.1 1.3 31.9 31 0 0 31 31 31 29 Sel1 repeat VHS PF00790.14 CEP08950.1 - 4.4e-20 71.7 2.8 1.4e-13 50.7 0.1 3.6 2 1 1 3 3 3 2 VHS domain FYVE PF01363.16 CEP08950.1 - 5.4e-18 64.6 8.9 1e-17 63.7 6.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUF202 PF02656.10 CEP08950.1 - 1.4e-06 28.3 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) UIM PF02809.15 CEP08950.1 - 9.6e-05 21.6 1.1 0.09 12.3 0.3 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Hrs_helical PF12210.3 CEP08950.1 - 0.0017 18.5 0.1 0.0037 17.4 0.1 1.5 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE_2 PF02318.11 CEP08950.1 - 0.0017 18.2 4.6 0.0017 18.2 3.2 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger HypA PF01155.14 CEP08950.1 - 0.17 11.6 2.3 0.4 10.3 1.6 1.6 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PEP-utilisers_N PF05524.8 CEP08950.1 - 0.21 11.4 1.5 0.89 9.3 0.5 2.2 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Band_7 PF01145.20 CEP08951.1 - 1.4e-25 90.2 2.4 2.2e-25 89.6 1.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 CEP08951.1 - 0.013 14.8 1.7 0.018 14.4 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) MgtE_N PF03448.12 CEP08951.1 - 0.14 12.4 2.4 13 6.1 0.3 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain DUF3811 PF11656.3 CEP08951.1 - 0.47 10.5 3.2 0.7 9.9 1.5 1.7 1 1 0 1 1 1 0 YjbD family (DUF3811) Bromodomain PF00439.20 CEP08952.1 - 2.1e-48 162.1 1.3 1.7e-23 82.3 0.1 2.7 2 0 0 2 2 2 2 Bromodomain FlxA PF14282.1 CEP08952.1 - 0.00038 20.3 9.8 0.00038 20.3 6.8 4.1 4 0 0 4 4 4 2 FlxA-like protein YL1 PF05764.8 CEP08952.1 - 0.00085 19.0 11.2 0.00085 19.0 7.8 2.7 3 0 0 3 3 3 1 YL1 nuclear protein ASC PF00858.19 CEP08952.1 - 0.0038 15.9 0.1 0.57 8.7 0.0 2.3 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel MerR-DNA-bind PF09278.6 CEP08952.1 - 1.8 9.0 5.6 1.8 9.0 1.1 2.8 3 0 0 3 3 3 0 MerR, DNA binding EB1 PF03271.12 CEP08953.1 - 4.7e-13 48.9 2.9 1.2e-12 47.6 2.0 1.7 1 1 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CEP08953.1 - 2.9e-05 24.0 0.1 5.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 CEP08953.1 - 0.0014 16.9 0.0 0.0018 16.5 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF948 PF06103.6 CEP08953.1 - 0.0064 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Ustilago_mating PF05722.7 CEP08953.1 - 0.028 13.7 0.1 0.039 13.2 0.1 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Suppressor_APC PF11414.3 CEP08953.1 - 0.074 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Bromodomain PF00439.20 CEP08954.1 - 1.4e-21 76.1 1.0 4.6e-21 74.5 0.7 1.9 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CEP08954.1 - 6.5e-09 35.8 0.2 1.5e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP08954.1 - 9.4e-07 28.7 0.1 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CEP08954.1 - 0.01 15.9 0.1 0.34 11.0 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TFIIE_beta PF02186.10 CEP08954.1 - 0.068 13.1 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 TFIIE beta subunit core domain TFIIF_alpha PF05793.7 CEP08954.1 - 9.2 4.4 43.6 15 3.7 30.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4240 PF14024.1 CEP08956.1 - 0.0099 15.7 0.3 0.43 10.4 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4240) Rad51 PF08423.6 CEP08957.1 - 9.9e-33 113.1 0.1 2.1e-32 112.0 0.1 1.5 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CEP08957.1 - 1.1e-10 41.2 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain HEAT PF02985.17 CEP08957.1 - 3.7e-09 35.9 10.9 0.00021 21.0 0.0 8.5 9 1 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.1 CEP08957.1 - 1.1e-08 35.1 0.4 0.0004 20.5 0.0 5.7 4 1 2 6 6 6 1 HEAT repeats HEAT_EZ PF13513.1 CEP08957.1 - 9.9e-08 32.2 0.1 5.9e-05 23.4 0.0 5.0 6 0 0 6 6 5 1 HEAT-like repeat KaiC PF06745.8 CEP08957.1 - 6.9e-07 28.6 0.6 2e-06 27.1 0.4 1.7 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 CEP08957.1 - 1.8e-05 24.8 0.0 7.6e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain IBN_N PF03810.14 CEP08957.1 - 0.013 15.3 0.4 0.13 12.2 0.2 2.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain Arm PF00514.18 CEP08957.1 - 0.014 15.2 0.1 0.014 15.2 0.0 4.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CEP08957.1 - 0.014 15.7 9.0 0.7 10.3 0.0 5.9 5 2 1 6 6 5 0 Vacuolar 14 Fab1-binding region PhoH PF02562.11 CEP08957.1 - 0.019 14.2 0.0 0.054 12.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein QueT PF06177.6 CEP08957.1 - 0.044 13.7 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 QueT transporter TRAP_alpha PF03896.11 CEP08958.1 - 1.1e-11 44.2 0.1 1.4e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1616 PF07760.6 CEP08958.1 - 0.065 12.3 0.3 0.52 9.4 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1616) Helitron_like_N PF14214.1 CEP08959.1 - 1.2e-17 64.2 0.0 2.1e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 CEP08959.1 - 0.0024 17.4 0.1 0.0083 15.7 0.0 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3296) PIF1 PF05970.9 CEP08961.1 - 1.9e-30 106.0 0.3 2.7e-21 75.9 0.0 2.4 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 CEP08961.1 - 8.3e-18 64.7 0.4 2.9e-16 59.7 0.1 2.5 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 CEP08961.1 - 5.8e-15 55.3 0.0 9.9e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CEP08961.1 - 2.9e-05 23.7 0.1 0.15 11.5 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CEP08961.1 - 0.0019 17.9 0.0 0.0047 16.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 CEP08961.1 - 0.0027 15.5 0.0 0.011 13.5 0.0 1.8 2 0 0 2 2 2 1 Helicase AAA_14 PF13173.1 CEP08961.1 - 0.0072 16.2 0.0 0.024 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 CEP08961.1 - 0.0094 16.0 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF3296 PF11726.3 CEP08961.1 - 0.015 14.9 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3296) PhoH PF02562.11 CEP08961.1 - 0.016 14.4 0.0 0.046 12.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 CEP08961.1 - 0.092 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Phage_GPA PF05840.8 CEP08961.1 - 0.1 11.2 1.5 0.61 8.7 1.0 2.0 1 1 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) AAA_22 PF13401.1 CEP08961.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Herpes_BLLF1 PF05109.8 CEP08962.1 - 0.14 10.0 21.8 0.16 9.8 15.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DPBB_1 PF03330.13 CEP08967.1 - 4.4e-14 52.2 0.0 6.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP08967.1 - 0.0003 20.4 0.1 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 CEP08968.1 - 2.8e-13 49.6 0.0 3.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP08968.1 - 0.0007 19.2 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Barwin family Kinesin PF00225.18 CEP08969.1 - 7.2e-57 192.5 0.7 7.2e-57 192.5 0.5 3.0 3 1 0 3 3 3 1 Kinesin motor domain Baculo_LEF-11 PF06385.7 CEP08969.1 - 0.081 13.0 2.9 0.52 10.4 1.7 2.7 2 1 0 2 2 2 0 Baculovirus LEF-11 protein Chal_sti_synt_N PF00195.14 CEP08969.1 - 0.76 8.9 4.2 0.23 10.6 0.3 1.9 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF1151 PF06625.6 CEP08969.1 - 1.7 8.3 19.3 2.7 7.7 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) EXOSC1 PF10447.4 CEP08971.1 - 2.7e-24 84.9 1.7 4.5e-24 84.2 1.2 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CEP08971.1 - 2.7e-12 45.7 0.3 2.7e-12 45.7 0.2 2.2 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 CEP08971.1 - 0.0047 16.9 0.8 0.049 13.7 0.6 2.3 1 1 0 1 1 1 1 S1 RNA binding domain Ricin_B_lectin PF00652.17 CEP08973.1 - 6.5e-14 52.0 0.1 2e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP08973.1 - 5.3e-12 46.0 0.1 5.2e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF3759 PF12585.3 CEP08973.1 - 0.064 13.1 0.1 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3759) BSD PF03909.12 CEP08974.1 - 1.9e-12 46.6 0.3 4.8e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 BSD domain Pil1 PF13805.1 CEP08974.1 - 0.022 13.9 0.9 0.048 12.8 0.6 1.6 1 0 0 1 1 1 0 Eisosome component PIL1 FlxA PF14282.1 CEP08974.1 - 0.04 13.8 0.5 0.04 13.8 0.3 2.6 2 0 0 2 2 2 0 FlxA-like protein IncA PF04156.9 CEP08974.1 - 0.043 13.4 0.3 0.043 13.4 0.2 1.7 2 0 0 2 2 2 0 IncA protein Rad17 PF03215.10 CEP08975.1 - 3.9e-47 161.1 5.8 1.3e-43 149.5 4.0 3.8 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 CEP08975.1 - 3.3e-06 27.3 0.0 7.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEP08975.1 - 7e-06 26.1 0.5 7.4e-05 22.8 0.0 2.3 2 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CEP08975.1 - 3.2e-05 24.7 0.0 0.00013 22.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CEP08975.1 - 0.00011 21.4 0.2 0.00075 18.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Sigma54_activ_2 PF14532.1 CEP08975.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 CEP08975.1 - 0.00012 22.2 0.6 0.0042 17.2 0.4 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CEP08975.1 - 0.00031 20.8 0.1 0.0044 17.1 0.0 2.8 2 1 0 2 2 2 1 RNA helicase DNA_pol3_delta PF06144.8 CEP08975.1 - 0.00033 20.1 1.2 0.0022 17.5 0.8 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit ABC_tran PF00005.22 CEP08975.1 - 0.00086 19.6 0.4 0.0023 18.2 0.3 2.2 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 CEP08975.1 - 0.0012 17.7 0.1 0.0031 16.4 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 CEP08975.1 - 0.0026 16.6 0.0 0.0055 15.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 CEP08975.1 - 0.0032 17.1 0.1 0.19 11.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 CEP08975.1 - 0.0046 17.2 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CEP08975.1 - 0.0046 16.8 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_P4 PF11602.3 CEP08975.1 - 0.0092 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 ATPase P4 of dsRNA bacteriophage phi-12 RuvB_N PF05496.7 CEP08975.1 - 0.0094 15.0 0.0 0.027 13.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 CEP08975.1 - 0.016 14.7 0.4 0.035 13.6 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CEP08975.1 - 0.019 14.7 0.1 0.05 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CEP08975.1 - 0.027 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 CEP08975.1 - 0.044 13.4 3.8 1.3 8.6 0.1 2.7 2 1 1 3 3 2 0 Archaeal ATPase SMC_N PF02463.14 CEP08975.1 - 0.066 12.4 0.3 0.24 10.5 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 CEP08975.1 - 0.11 12.3 1.8 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 CEP08975.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 CEP08975.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CEP08975.1 - 0.2 10.4 0.2 0.51 9.0 0.1 1.5 1 1 0 1 1 1 0 ArgK protein AAA_23 PF13476.1 CEP08975.1 - 0.72 10.1 7.0 0.68 10.2 2.2 2.6 2 1 0 2 2 2 0 AAA domain Glutaredoxin PF00462.19 CEP08976.1 - 6.7e-19 67.6 0.1 1.9e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Zn_ribbon_2 PF12674.2 CEP08976.1 - 0.019 15.3 0.1 0.029 14.7 0.1 1.4 1 1 0 1 1 1 0 Putative zinc ribbon domain DUF836 PF05768.9 CEP08976.1 - 0.024 14.8 0.1 0.076 13.2 0.0 1.8 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 CEP08976.1 - 0.073 12.6 1.3 0.36 10.3 0.5 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 CEP08976.1 - 0.082 13.1 0.5 0.16 12.1 0.4 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain GRAM PF02893.15 CEP08977.1 - 4e-14 51.8 0.0 8.6e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Retrotrans_gag PF03732.12 CEP08978.1 - 3.8e-05 23.6 1.0 0.0001 22.3 0.1 2.1 2 1 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.19 CEP08979.1 - 1.3e-11 43.9 0.5 3.1e-11 42.7 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP08979.1 - 0.012 15.3 0.1 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Avidin PF01382.12 CEP08979.1 - 0.061 13.6 0.2 0.13 12.5 0.0 1.5 2 0 0 2 2 2 0 Avidin family Neuromodulin_N PF10580.4 CEP08979.1 - 0.41 10.3 4.9 0.76 9.4 0.1 2.5 2 0 0 2 2 2 0 Gap junction protein N-terminal region RVT_1 PF00078.22 CEP08980.1 - 1.1e-09 37.9 0.0 1.6e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAM2 PF07145.10 CEP08980.1 - 0.0056 16.0 0.4 0.0056 16.0 0.3 2.4 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Aldedh PF00171.17 CEP08981.1 - 7e-69 232.3 0.1 7.7e-69 232.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CEP08981.1 - 0.027 13.7 0.1 0.038 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Nepo_coat_N PF03689.10 CEP08981.1 - 0.13 11.9 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain DDE_3 PF13358.1 CEP08983.1 - 9.9e-29 99.9 0.0 2.3e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP08983.1 - 4.6e-09 36.4 0.1 1.5e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP08983.1 - 5.9e-07 30.2 0.3 1.6e-06 28.7 0.0 2.0 2 0 0 2 2 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP08983.1 - 6.5e-06 26.0 4.3 2e-05 24.4 0.3 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP08983.1 - 0.0001 21.8 1.9 0.0011 18.5 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 CEP08983.1 - 0.00078 19.5 0.0 0.0044 17.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_1 PF01527.15 CEP08983.1 - 0.012 15.5 1.3 0.044 13.7 0.0 2.3 2 1 1 3 3 3 0 Transposase HTH_17 PF12728.2 CEP08983.1 - 0.012 15.8 0.1 1.3 9.3 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 CEP08983.1 - 0.1 11.8 0.1 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 CEP08983.1 - 0.15 11.6 0.1 0.35 10.4 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Terminase_5 PF06056.7 CEP08983.1 - 0.32 10.5 2.1 0.5 9.9 0.0 2.4 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) MFS_1 PF07690.11 CEP08984.1 - 4e-21 75.1 22.3 4.9e-21 74.8 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.3 CEP08984.1 - 0.015 14.5 0.2 0.32 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) HMG_box_2 PF09011.5 CEP08984.1 - 0.031 14.6 0.4 0.059 13.7 0.3 1.4 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.14 CEP08984.1 - 0.11 12.7 1.0 0.23 11.7 0.7 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box DUF1228 PF06779.9 CEP08984.1 - 0.13 12.2 2.5 0.13 12.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) DUF308 PF03729.8 CEP08984.1 - 0.68 9.9 14.3 2.2 8.3 4.8 3.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) RVT_1 PF00078.22 CEP08986.1 - 1.7e-16 60.2 0.1 2.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-R PF06729.7 CEP08986.1 - 0.043 13.4 2.4 0.11 12.2 0.2 2.1 2 0 0 2 2 2 0 Kinetochore component, CENP-R Tropomyosin_1 PF12718.2 CEP08988.1 - 0.0076 16.1 1.3 0.015 15.1 0.9 1.4 1 0 0 1 1 1 1 Tropomyosin like Fib_alpha PF08702.5 CEP08988.1 - 0.5 10.4 3.4 1.1 9.3 2.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pex14_N PF04695.8 CEP08989.1 - 0.059 13.4 3.3 0.096 12.7 2.3 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4603 PF15376.1 CEP08989.1 - 0.72 6.9 4.2 0.77 6.8 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) zf-CCHC PF00098.18 CEP08990.1 - 0.00031 20.5 3.8 0.00031 20.5 2.6 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP08990.1 - 0.016 14.8 5.2 2.5 7.8 1.6 2.7 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 CEP08991.1 - 2.5e-35 121.7 0.0 6.2e-35 120.5 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FTA4 PF13093.1 CEP08991.1 - 0.018 14.4 0.1 0.036 13.5 0.1 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Exo_endo_phos_2 PF14529.1 CEP08991.1 - 0.034 13.7 0.5 0.077 12.6 0.3 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP08991.1 - 0.27 11.1 2.5 0.51 10.2 1.8 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CEP08992.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP08993.1 - 5.6e-15 55.2 0.0 1.4e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP08993.1 - 1.6e-08 34.7 0.2 3.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP08993.1 - 2.7e-07 30.1 0.7 8.6e-07 28.5 0.5 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC_4 PF14392.1 CEP08993.1 - 0.001 18.7 8.8 0.12 12.0 0.0 2.8 2 0 0 2 2 2 2 Zinc knuckle rve_2 PF13333.1 CEP08993.1 - 0.13 12.3 0.1 0.43 10.6 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.18 CEP08993.1 - 0.36 10.8 14.2 0.54 10.2 2.2 2.6 2 0 0 2 2 2 0 Zinc knuckle BRO1 PF03097.13 CEP08994.1 - 9.7e-85 284.5 1.2 9.7e-85 284.5 0.8 2.3 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CEP08994.1 - 6.8e-64 215.6 17.3 1.2e-63 214.8 12.0 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV LRR_8 PF13855.1 CEP08994.1 - 0.085 12.6 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Leucine rich repeat RVT_1 PF00078.22 CEP08995.1 - 1.1e-12 47.8 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CEP08997.1 - 0.00012 21.7 0.3 0.00021 20.8 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Exo_endo_phos PF03372.18 CEP08998.1 - 1.3e-13 51.4 0.3 3.4e-13 50.1 0.2 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP08998.1 - 2.9e-08 33.3 0.6 2.9e-08 33.3 0.4 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 CEP08998.1 - 6.4e-08 32.2 0.1 1.5e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_2 PF07992.9 CEP09000.1 - 6.1e-09 36.0 0.0 1.2e-07 31.7 0.0 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP09000.1 - 9.8e-07 29.0 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP09000.1 - 0.038 12.9 0.0 0.14 11.0 0.0 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein K_oxygenase PF13434.1 CEP09000.1 - 0.043 12.7 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CEP09000.1 - 0.054 13.5 0.0 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.14 CEP09000.1 - 0.11 11.5 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.13 CEP09000.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.11 CEP09001.1 - 1.5e-17 63.3 47.3 1.7e-15 56.6 32.3 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Cation_efflux PF01545.16 CEP09003.1 - 1.4e-78 263.8 5.5 1.8e-78 263.5 3.8 1.1 1 0 0 1 1 1 1 Cation efflux family Sterol-sensing PF12349.3 CEP09004.1 - 5.5e-22 77.8 4.2 1.2e-21 76.8 2.9 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Arrestin_N PF00339.24 CEP09004.1 - 1.8e-18 66.7 0.0 5.9e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP09004.1 - 2.1e-18 66.7 0.7 4.6e-16 59.1 0.0 3.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Patched PF02460.13 CEP09004.1 - 2.9e-11 42.0 4.2 4.5e-11 41.4 2.9 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 CEP09004.1 - 1.6e-08 34.1 5.0 0.045 13.6 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.3 CEP09004.1 - 2.3e-05 22.7 1.9 0.015 13.4 0.0 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 LDB19 PF13002.2 CEP09004.1 - 0.0061 16.0 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like DUF912 PF06024.7 CEP09005.1 - 0.022 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 CEP09006.1 - 2.3e-29 100.1 3.8 2.2e-08 33.6 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 CEP09006.1 - 2.2e-05 24.2 0.1 0.2 11.3 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CEP09006.1 - 0.012 15.0 0.0 6.1 6.4 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.1 CEP09006.1 - 0.053 13.8 0.5 1.4 9.3 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain Hira PF07569.6 CEP09006.1 - 0.095 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split Abhydrolase_6 PF12697.2 CEP09007.1 - 2.5e-25 89.7 0.0 3.2e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP09007.1 - 4.9e-19 68.5 0.0 1.2e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CEP09007.1 - 5.2e-09 35.7 0.0 2.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 CEP09007.1 - 1.2e-08 34.8 0.0 0.00039 20.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CEP09007.1 - 2.7e-08 33.5 0.0 4.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CEP09007.1 - 3e-05 23.3 0.0 0.0084 15.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2920 PF11144.3 CEP09007.1 - 5.8e-05 22.2 0.0 0.00034 19.7 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.8 CEP09007.1 - 0.00062 19.4 0.0 0.0035 16.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 CEP09007.1 - 0.0025 16.7 0.0 0.47 9.2 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Esterase PF00756.15 CEP09007.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 CEP09007.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 CEP09007.1 - 0.041 12.6 0.0 0.61 8.8 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase DUF4360 PF14273.1 CEP09007.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) EamA PF00892.15 CEP09008.1 - 0.00014 21.9 9.9 0.00044 20.2 6.8 1.8 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 CEP09008.1 - 0.00025 20.8 1.5 0.00029 20.6 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 UAA PF08449.6 CEP09008.1 - 0.00042 19.3 3.8 0.00047 19.1 2.6 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CEP09008.1 - 0.015 14.9 7.5 0.023 14.3 5.2 1.3 1 1 0 1 1 1 0 Triose-phosphate Transporter family EmrE PF13536.1 CEP09008.1 - 0.12 12.6 10.9 0.24 11.6 7.1 1.7 1 1 0 1 1 1 0 Multidrug resistance efflux transporter Colicin_V PF02674.11 CEP09008.1 - 0.19 11.5 3.4 0.18 11.6 1.6 1.4 1 1 0 1 1 1 0 Colicin V production protein Nup54 PF13874.1 CEP09009.1 - 2.8e-29 101.6 11.2 5.8e-29 100.5 7.8 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CEP09009.1 - 1.5 9.1 132.4 3e+03 -1.6 36.4 3.8 1 1 1 2 2 2 0 Nucleoporin FG repeat region Polysacc_deac_1 PF01522.16 CEP09010.1 - 4.4e-09 36.0 0.0 1.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase FA_hydroxylase PF04116.8 CEP09011.1 - 4.7e-12 46.3 25.2 4.7e-12 46.3 17.5 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MOSC_N PF03476.11 CEP09012.1 - 3.1e-22 78.5 0.0 4.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CEP09012.1 - 1.1e-14 54.0 0.0 1.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MMS19_N PF14500.1 CEP09013.1 - 1.2e-72 244.3 3.2 6.9e-71 238.5 0.1 4.1 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CEP09013.1 - 1.7e-58 198.3 23.9 1.1e-48 166.0 6.0 4.6 4 2 1 5 5 5 3 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 CEP09013.1 - 1.3e-07 31.8 7.0 0.0015 18.7 0.2 5.4 4 2 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 CEP09013.1 - 0.0033 17.8 0.2 0.0033 17.8 0.1 5.5 5 2 2 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CEP09013.1 - 0.021 15.2 0.5 0.56 10.6 0.0 3.6 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region ParcG PF10274.4 CEP09013.1 - 0.031 14.1 0.6 0.031 14.1 0.4 2.6 3 0 0 3 3 3 0 Parkin co-regulated protein ATP-cone PF03477.11 CEP09013.1 - 0.06 13.7 0.0 18 5.8 0.1 3.1 2 0 0 2 2 2 0 ATP cone domain HEAT PF02985.17 CEP09013.1 - 0.15 12.2 2.5 42 4.6 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat SH3_9 PF14604.1 CEP09015.1 - 7.5e-32 108.6 0.2 1.5e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CEP09015.1 - 2.2e-28 97.4 0.5 4.1e-17 61.3 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CEP09015.1 - 1.8e-21 75.3 0.1 9.2e-13 47.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 CEP09015.1 - 3.6e-19 68.7 1.0 3.6e-19 68.7 0.7 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 CEP09015.1 - 6.5e-12 44.9 7.7 1.1e-11 44.3 5.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Img2 PF05046.9 CEP09015.1 - 0.11 12.7 0.3 0.51 10.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Syntaxin PF00804.20 CEP09015.1 - 0.59 10.3 9.7 1.1 9.3 0.0 3.8 4 0 0 4 4 4 0 Syntaxin Fib_alpha PF08702.5 CEP09015.1 - 0.9 9.6 0.0 0.9 9.6 0.0 4.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family RICH PF05062.7 CEP09015.1 - 4 7.6 9.7 1.1 9.3 0.1 3.4 4 0 0 4 4 4 0 RICH domain Retrotrans_gag PF03732.12 CEP09016.1 - 0.0003 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Hydrolase_6 PF13344.1 CEP09016.1 - 0.04 13.8 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PIF1 PF05970.9 CEP09018.1 - 3.3e-22 78.9 0.1 4.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP09018.1 - 1.9e-07 29.2 0.0 2.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP09018.1 - 1.5e-06 28.2 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2672 PF10878.3 CEP09018.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) zf-CCHC PF00098.18 CEP09021.1 - 0.00012 21.8 3.6 0.00021 21.0 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEP09021.1 - 0.0009 19.2 0.0 0.005 16.8 0.0 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein Acetyltransf_4 PF13420.1 CEP09021.1 - 0.0035 17.2 0.7 0.0079 16.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain TMF_DNA_bd PF12329.3 CEP09021.1 - 6.8 6.5 10.0 0.086 12.6 1.3 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding rve PF00665.21 CEP09022.1 - 7.1e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP09022.1 - 0.012 14.9 0.5 0.025 13.9 0.4 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Helitron_like_N PF14214.1 CEP09023.1 - 2e-42 144.9 0.4 9.8e-29 100.3 0.0 2.3 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 CEP09023.1 - 0.0044 16.6 0.5 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3296) DNA_RNApol_7kD PF03604.8 CEP09024.1 - 0.013 14.9 0.2 0.066 12.6 0.0 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Clathrin_propel PF01394.15 CEP09024.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Clathrin propeller repeat zf-C3HC4_2 PF13923.1 CEP09025.1 - 9.1e-08 32.0 18.5 1.8e-07 31.0 8.4 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP09025.1 - 2.5e-05 23.8 15.7 0.00024 20.7 5.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP09025.1 - 0.00029 20.6 20.6 0.00055 19.6 8.5 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CEP09025.1 - 0.0014 18.2 11.7 0.0014 18.2 8.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RasGAP_C PF03836.10 CEP09025.1 - 0.0047 16.6 2.2 0.013 15.1 1.5 1.9 1 0 0 1 1 1 1 RasGAP C-terminus zf-RING_5 PF14634.1 CEP09025.1 - 0.012 15.2 10.0 0.012 15.2 6.9 3.1 3 0 0 3 3 3 0 zinc-RING finger domain LMWPc PF01451.16 CEP09025.1 - 0.053 13.8 0.2 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase zf-Apc11 PF12861.2 CEP09025.1 - 0.76 9.6 10.2 0.23 11.3 4.2 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CEP09025.1 - 2.9 8.0 16.3 31 4.7 0.1 3.7 3 1 0 3 3 3 0 RING-H2 zinc finger DZR PF12773.2 CEP09025.1 - 3.2 7.6 11.0 0.94 9.3 0.9 3.5 4 0 0 4 4 4 0 Double zinc ribbon zf-Nse PF11789.3 CEP09025.1 - 5.9 6.4 10.8 0.28 10.7 3.3 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Paralemmin PF03285.10 CEP09026.1 - 0.21 11.0 3.3 0.24 10.8 1.7 1.4 2 0 0 2 2 2 0 Paralemmin RVP PF00077.15 CEP09028.1 - 0.1 12.5 0.2 0.62 10.0 0.1 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease BHD_3 PF10405.4 CEP09031.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 rve PF00665.21 CEP09032.1 - 1.4e-22 80.0 0.0 4.1e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP09032.1 - 8.4e-11 41.6 0.0 1.7e-09 37.3 0.0 2.5 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CEP09032.1 - 0.00024 20.5 0.0 0.00063 19.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Exo_endo_phos PF03372.18 CEP09033.1 - 2.5e-07 30.8 0.1 2.8e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_11 PF13414.1 CEP09034.1 - 0.05 13.2 2.8 7.2 6.3 0.1 2.8 2 0 0 2 2 2 0 TPR repeat PACT_coil_coil PF10495.4 CEP09034.1 - 0.096 12.6 1.4 0.24 11.3 1.0 1.6 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein CotH PF08757.6 CEP09035.1 - 5.5e-35 121.1 9.3 9.2e-35 120.4 6.4 1.3 1 0 0 1 1 1 1 CotH protein JHBP PF06585.6 CEP09035.1 - 0.0065 15.3 1.8 0.2 10.4 0.0 2.2 2 0 0 2 2 2 2 Haemolymph juvenile hormone binding protein (JHBP) IKKbetaNEMObind PF12179.3 CEP09035.1 - 0.14 11.9 0.1 0.52 10.1 0.1 1.8 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DUF1752 PF08550.5 CEP09036.1 - 1.3e-12 47.0 0.4 2.9e-12 45.9 0.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GCR1_C PF12550.3 CEP09037.1 - 4.4e-16 58.5 0.3 7.7e-16 57.7 0.2 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Med12-LCEWAV PF12145.3 CEP09037.1 - 0.0049 15.4 0.6 1.2 7.5 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic Mediator 12 subunit domain GLYCAM-1 PF05242.6 CEP09037.1 - 0.02 14.8 1.3 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) FliL PF03748.9 CEP09037.1 - 0.032 14.2 0.6 0.063 13.2 0.4 1.5 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL RRS1 PF04939.7 CEP09037.1 - 0.036 13.5 1.7 0.039 13.4 0.1 1.8 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) SPX PF03105.14 CEP09037.1 - 0.054 13.2 0.5 0.066 12.9 0.4 1.2 1 0 0 1 1 1 0 SPX domain CTP_transf_1 PF01148.15 CEP09039.1 - 2.2e-69 233.9 25.9 3.1e-69 233.5 18.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Gemini_coat PF00844.13 CEP09039.1 - 0.066 12.4 0.4 0.13 11.4 0.1 1.5 1 1 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family CPSase_L_D2 PF02786.12 CEP09041.1 - 4.1e-107 356.2 0.0 1.4e-82 276.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CEP09041.1 - 8.9e-38 128.8 0.2 6.9e-37 125.9 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CEP09041.1 - 2.5e-37 127.3 0.0 4e-17 62.3 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CEP09041.1 - 3.3e-33 114.9 0.1 9.1e-17 61.3 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP09041.1 - 8.3e-19 67.4 0.0 3.3e-07 29.3 0.0 4.9 4 1 0 4 4 4 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CEP09041.1 - 2.2e-14 53.2 0.0 7.3e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CEP09041.1 - 4.5e-12 45.7 0.1 4.5e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 CEP09041.1 - 5.8e-09 35.6 0.0 4.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 CEP09041.1 - 9e-05 21.7 0.0 0.0037 16.4 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.17 CEP09041.1 - 0.038 13.9 0.0 0.39 10.6 0.0 2.6 2 0 0 2 2 2 0 MGS-like domain TrkA_N PF02254.13 CEP09041.1 - 0.045 13.7 0.1 0.85 9.6 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Cut8_N PF14482.1 CEP09042.1 - 5.3 7.1 6.1 2.7 8.0 2.1 2.1 2 1 0 2 2 2 0 Cut8 proteasome-binding domain Synaptobrevin PF00957.16 CEP09043.1 - 4e-15 55.1 0.2 6.8e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CEP09043.1 - 1e-12 47.4 0.0 1.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Phytochelatin PF05023.9 CEP09044.1 - 6e-77 257.4 0.0 8.9e-77 256.8 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.1 CEP09044.1 - 0.0087 16.4 0.0 0.034 14.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C14 PF00656.17 CEP09045.1 - 3.5e-59 200.4 0.1 6.4e-59 199.6 0.1 1.4 1 0 0 1 1 1 1 Caspase domain Fungal_trans PF04082.13 CEP09045.1 - 4.4e-19 68.3 0.1 3.7e-16 58.7 0.0 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 CEP09046.1 - 2.6e-23 81.9 0.0 4.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Endonuc-dimeris PF09124.5 CEP09046.1 - 0.0047 16.5 0.1 1 9.0 0.0 2.5 2 0 0 2 2 2 2 T4 recombination endonuclease VII, dimerisation CAP_N PF01213.14 CEP09047.1 - 8.1e-92 307.8 15.4 1e-91 307.4 10.3 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CEP09047.1 - 3.6e-60 201.9 8.3 5.2e-60 201.3 5.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CEP09047.1 - 0.0012 18.2 4.4 0.0043 16.4 2.8 1.9 1 1 0 1 1 1 1 Tubulin binding cofactor C Mito_fiss_reg PF05308.6 CEP09047.1 - 1.9 7.8 17.7 4.5 6.5 7.4 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Aldedh PF00171.17 CEP09048.1 - 2.1e-77 260.4 0.0 2.6e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CEP09048.1 - 0.038 12.7 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Anp1 PF03452.9 CEP09049.1 - 5.4e-81 271.6 0.1 6.6e-81 271.3 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CEP09049.1 - 6.5e-05 22.6 0.1 0.02 14.5 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 FAR1 PF03101.10 CEP09050.1 - 1.3e-09 38.4 2.2 2.2e-09 37.6 1.5 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AAA_21 PF13304.1 CEP09050.1 - 1 9.2 5.5 5.4 6.8 0.7 2.1 2 0 0 2 2 2 0 AAA domain zinc_ribbon_6 PF14599.1 CEP09051.1 - 0.14 11.9 4.4 2.2 8.1 0.9 3.0 2 1 0 2 2 2 0 Zinc-ribbon PyrI_C PF02748.10 CEP09051.1 - 0.16 11.3 5.7 1.1 8.7 0.8 2.9 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_4 PF07975.7 CEP09051.1 - 0.73 9.8 7.6 18 5.4 1.7 3.4 2 1 1 3 3 3 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 CEP09051.1 - 0.74 9.6 7.6 0.88 9.4 0.9 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.10 CEP09051.1 - 1 9.2 9.1 9.9 6.0 1.1 3.6 4 0 0 4 4 4 0 BED zinc finger zf-H2C2_2 PF13465.1 CEP09051.1 - 1.5 9.2 7.0 1.4 9.3 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain AAA_11 PF13086.1 CEP09052.1 - 1.3e-12 47.8 0.3 7.1e-06 25.7 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 CEP09052.1 - 2.8e-05 23.7 0.0 0.22 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CEP09052.1 - 3.8e-05 23.3 0.0 0.0019 17.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Cas_Cas4 PF01930.12 CEP09052.1 - 0.00046 20.1 1.4 0.0084 16.0 0.0 3.0 1 1 1 2 2 2 1 Domain of unknown function DUF83 AAA_22 PF13401.1 CEP09052.1 - 0.042 13.9 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4550 PF15084.1 CEP09052.1 - 0.046 13.8 0.4 0.83 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) GreA_GreB_N PF03449.10 CEP09054.1 - 0.24 11.4 0.2 0.24 11.4 0.1 3.2 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal IncA PF04156.9 CEP09054.1 - 0.96 9.0 5.6 0.52 9.8 2.4 1.6 2 0 0 2 2 2 0 IncA protein IPPT PF01715.12 CEP09055.1 - 0.098 11.6 0.3 0.11 11.4 0.2 1.0 1 0 0 1 1 1 0 IPP transferase Exo_endo_phos PF03372.18 CEP09056.1 - 1.5e-10 41.4 0.4 1.9e-10 41.1 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP09056.1 - 1.3e-07 31.2 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Tetrabrachion PF11401.3 CEP09057.1 - 0.091 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Tetrabrachion RVT_1 PF00078.22 CEP09058.1 - 2.5e-13 49.9 0.0 3.1e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RdRP_1 PF00680.15 CEP09058.1 - 0.026 12.7 0.0 0.029 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Pex26 PF07163.7 CEP09059.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Pex26 protein Chromo PF00385.19 CEP09062.1 - 3.2e-07 29.9 0.1 6.9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP09062.1 - 0.096 12.4 0.6 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain RVT_1 PF00078.22 CEP09068.1 - 1.2e-21 77.0 0.1 3.6e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAS_11 PF14598.1 CEP09068.1 - 0.0074 16.2 0.4 0.088 12.7 0.0 2.6 3 0 0 3 3 3 1 PAS domain Sec66 PF09802.4 CEP09068.1 - 0.014 14.7 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF677 PF05055.7 CEP09068.1 - 0.33 9.5 1.2 0.37 9.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF677) Phage_integrase PF00589.17 CEP09069.1 - 0.0062 16.2 0.0 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Cas1_AcylT PF07779.7 CEP09070.1 - 2.5e-146 487.9 30.1 4.4e-146 487.1 20.9 1.3 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 CEP09070.1 - 4.5e-26 92.2 0.4 9.3e-26 91.2 0.3 1.6 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Dispanin PF04505.7 CEP09070.1 - 0.018 14.5 0.6 0.089 12.3 0.4 2.2 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Sec10 PF07393.6 CEP09071.1 - 2.5e-182 607.7 5.6 4e-182 607.1 3.9 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec10 SET PF00856.23 CEP09072.1 - 0.097 12.9 0.3 8.8 6.6 0.0 2.5 1 1 1 2 2 2 0 SET domain Ferrochelatase PF00762.14 CEP09073.1 - 4.3e-109 364.3 0.0 5.1e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 CEP09073.1 - 0.0095 16.0 0.0 5 7.2 0.0 3.4 3 0 0 3 3 3 1 CbiX LLC1 PF14945.1 CEP09073.1 - 0.049 13.9 0.2 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Peptidase_M24 PF00557.19 CEP09074.1 - 6.3e-44 150.0 0.0 1.1e-43 149.2 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 ERK-JNK_inhib PF15002.1 CEP09074.1 - 0.82 9.0 8.3 1.8 7.8 5.8 1.6 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor DUF3391 PF11871.3 CEP09074.1 - 1.7 8.8 6.3 1.2 9.3 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) LUC7 PF03194.10 CEP09074.1 - 8.3 5.8 8.7 32 3.9 6.1 2.1 1 1 0 1 1 1 0 LUC7 N_terminus mRNA_cap_enzyme PF01331.14 CEP09075.1 - 1.1e-47 162.2 0.2 1.1e-46 158.9 0.1 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CEP09075.1 - 4.2e-17 62.3 0.0 1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CEP09075.1 - 4.3e-08 32.7 0.2 4.3e-06 26.2 0.1 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Nucleoporin2 PF04096.9 CEP09076.1 - 9.1e-45 151.9 0.0 1.4e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CEP09076.1 - 0.0024 18.0 315.6 0.004 17.3 38.2 9.4 3 2 3 6 6 6 3 Nucleoporin FG repeat region zf-RVT PF13966.1 CEP09077.1 - 4.1e-06 27.0 0.4 7.5e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF2256 PF10013.4 CEP09077.1 - 0.027 14.2 0.3 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) CSD PF00313.17 CEP09078.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF2457 PF10446.4 CEP09079.1 - 9.7e-05 21.2 27.3 0.00014 20.7 18.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 CEP09079.1 - 0.00011 20.3 20.6 0.00012 20.1 14.3 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 CEP09079.1 - 0.00033 19.3 17.8 0.00039 19.0 12.3 1.1 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 CEP09079.1 - 0.0033 15.5 16.2 0.0042 15.1 11.2 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIA PF03153.8 CEP09079.1 - 0.0067 16.3 19.5 0.0077 16.1 13.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.7 CEP09079.1 - 0.018 14.3 23.9 0.024 13.9 16.6 1.2 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 CEP09079.1 - 0.096 11.9 15.0 0.11 11.6 10.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 CEP09079.1 - 0.13 11.5 16.5 0.24 10.7 11.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_LMP1 PF05297.6 CEP09079.1 - 0.54 9.1 16.4 0.62 8.9 11.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) YL1 PF05764.8 CEP09079.1 - 1.4 8.5 19.1 2.1 7.9 13.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 CEP09079.1 - 1.5 7.8 21.7 2 7.4 15.1 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.7 CEP09079.1 - 3.9 5.7 25.6 5.4 5.2 17.7 1.1 1 0 0 1 1 1 0 Mpp10 protein RRN3 PF05327.6 CEP09079.1 - 4.9 5.1 15.0 6.4 4.7 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Upf2 PF04050.9 CEP09079.1 - 6 6.5 22.4 12 5.6 15.5 1.5 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Astro_capsid PF03115.9 CEP09079.1 - 8.3 4.5 8.9 13 3.9 6.2 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Cas_Csa4 PF09703.5 CEP09080.1 - 0.12 11.2 3.3 0.25 10.2 2.3 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) DUF2937 PF11157.3 CEP09080.1 - 3.8 6.8 4.8 11 5.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Med27 PF11571.3 CEP09081.1 - 4.9e-16 58.6 0.6 1.4e-15 57.1 0.4 1.8 1 0 0 1 1 1 1 Mediator complex subunit 27 HECT_2 PF09814.4 CEP09082.1 - 3.8e-46 157.4 4.4 5.5e-46 156.9 3.1 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_5 PF13719.1 CEP09082.1 - 0.0084 15.6 2.0 0.11 12.1 0.1 2.5 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CEP09082.1 - 0.014 15.1 2.1 0.18 11.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.1 CEP09082.1 - 0.056 13.2 1.8 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Elf1 PF05129.8 CEP09082.1 - 0.16 11.6 0.9 0.42 10.3 0.1 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like LRR_4 PF12799.2 CEP09083.1 - 0.00013 21.4 6.6 0.0095 15.5 0.1 4.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP09083.1 - 0.0012 18.5 5.2 12 6.3 0.1 5.4 4 2 1 5 5 5 2 Leucine Rich Repeat F-box-like PF12937.2 CEP09083.1 - 0.0019 17.8 0.7 0.0019 17.8 0.5 2.0 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 CEP09083.1 - 0.0041 17.0 11.6 9.1 6.7 0.1 5.7 6 1 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.1 CEP09083.1 - 0.083 12.6 9.9 4.2 7.2 1.7 4.1 2 2 1 3 3 3 0 Leucine rich repeat CLIP PF12032.3 CEP09083.1 - 0.18 11.9 1.6 12 6.0 0.0 3.0 2 1 0 2 2 2 0 Regulatory CLIP domain of proteinases LRR_7 PF13504.1 CEP09083.1 - 0.71 10.3 13.3 6.1 7.5 0.0 5.6 6 1 0 6 6 6 0 Leucine rich repeat Ytp1 PF10355.4 CEP09084.1 - 8.2e-65 218.6 13.1 1.5e-64 217.7 9.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CEP09084.1 - 7.8e-25 86.4 5.7 7.8e-25 86.4 3.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 CEP09084.1 - 0.0003 20.6 9.7 0.0003 20.6 6.8 3.2 3 1 0 3 3 3 1 Eukaryotic cytochrome b561 DUF1201 PF06716.6 CEP09084.1 - 0.24 11.2 3.4 0.34 10.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) DUF4328 PF14219.1 CEP09084.1 - 0.25 10.6 11.0 0.18 11.0 1.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) Kelch_3 PF13415.1 CEP09085.1 - 7.7e-08 32.3 10.7 0.0023 18.0 0.6 5.0 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP09085.1 - 5.3e-06 26.3 18.3 6.7e-05 22.8 0.4 5.7 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CEP09085.1 - 1.4e-05 24.7 9.8 0.00015 21.4 0.4 5.1 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP09085.1 - 1.4e-05 24.6 1.0 0.52 10.1 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 CEP09085.1 - 5.1e-05 22.7 0.9 5.1e-05 22.7 0.6 4.6 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CEP09085.1 - 0.0024 17.7 11.2 5.1 7.1 0.0 5.6 6 0 0 6 6 6 1 Kelch motif VSP PF03302.8 CEP09085.1 - 0.0072 15.0 0.3 0.011 14.4 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 CEP09085.1 - 0.027 13.7 1.5 0.058 12.7 1.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 CEP09085.1 - 0.028 13.9 0.5 0.028 13.9 0.4 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Plasmod_MYXSPDY PF07981.6 CEP09085.1 - 7.9 6.2 8.8 15 5.4 3.4 2.6 2 0 0 2 2 2 0 Plasmodium repeat_MYXSPDY HTH_29 PF13551.1 CEP09087.1 - 0.0001 22.4 0.2 0.00023 21.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP09087.1 - 0.0014 19.3 0.0 0.0057 17.4 0.0 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP09087.1 - 0.0072 16.2 1.0 0.015 15.2 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 CEP09087.1 - 0.026 13.6 0.0 0.095 11.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Helitron_like_N PF14214.1 CEP09088.1 - 4.1e-34 117.9 0.3 8.2e-23 81.0 0.0 2.5 2 0 0 2 2 2 2 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 CEP09088.1 - 0.071 11.8 0.5 0.65 8.6 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage replication gene A protein (GPA) Phage_int_SAM_5 PF13102.1 CEP09089.1 - 0.099 12.6 0.9 0.28 11.1 0.2 2.0 2 1 1 3 3 3 0 Phage integrase SAM-like domain Leo1 PF04004.8 CEP09090.1 - 3.5e-45 153.7 0.3 3.5e-45 153.7 0.2 2.7 3 0 0 3 3 3 1 Leo1-like protein rve PF00665.21 CEP09094.1 - 1e-17 64.3 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CEP09094.1 - 0.00093 19.1 0.2 0.0011 18.9 0.2 1.1 1 0 0 1 1 1 1 DDE domain DUF845 PF05820.6 CEP09094.1 - 0.0073 16.0 0.3 0.013 15.2 0.2 1.5 1 1 0 1 1 1 1 Baculovirus protein of unknown function (DUF845) Asp_protease_2 PF13650.1 CEP09096.1 - 0.00012 22.5 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CEP09096.1 - 0.00052 19.5 0.0 0.00089 18.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP09096.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 CEP09096.1 - 0.031 14.3 0.2 0.066 13.2 0.1 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein ELH PF02323.10 CEP09097.1 - 0.26 10.4 2.8 0.31 10.1 2.0 1.0 1 0 0 1 1 1 0 Egg-laying hormone precursor NOA36 PF06524.7 CEP09097.1 - 1.9 7.6 6.6 2.1 7.5 4.6 1.0 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 CEP09097.1 - 2.8 6.8 5.8 2.7 6.9 4.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cwf_Cwc_15 PF04889.7 CEP09097.1 - 4.5 6.9 9.3 5.1 6.7 6.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sipho_Gp157 PF05565.6 CEP09098.1 - 0.0086 15.6 0.1 0.0099 15.4 0.1 1.0 1 0 0 1 1 1 1 Siphovirus Gp157 Baculo_helicase PF04735.7 CEP09098.1 - 0.12 9.6 0.2 0.13 9.6 0.2 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase SET PF00856.23 CEP09099.1 - 1.7e-25 90.2 1.2 1.8e-24 86.8 0.9 2.4 1 1 0 1 1 1 1 SET domain GATA PF00320.22 CEP09099.1 - 5.7e-17 60.7 13.9 3.1e-12 45.6 3.8 2.9 2 0 0 2 2 2 2 GATA zinc finger DDE_3 PF13358.1 CEP09100.1 - 2.3e-05 24.1 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Usp PF00582.21 CEP09102.1 - 7e-27 94.3 0.1 4.8e-26 91.6 0.1 1.8 1 1 0 1 1 1 1 Universal stress protein family CorA PF01544.13 CEP09103.1 - 2.5e-08 33.2 1.4 4.4e-08 32.5 1.0 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein IncA PF04156.9 CEP09103.1 - 0.13 11.8 3.3 0.37 10.3 2.3 1.9 1 1 0 1 1 1 0 IncA protein SCP2 PF02036.12 CEP09104.1 - 2.4e-09 37.4 0.5 4.6e-09 36.4 0.4 1.5 1 1 0 1 1 1 1 SCP-2 sterol transfer family DUF3344 PF11824.3 CEP09104.1 - 0.097 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) ACOX PF01756.14 CEP09105.1 - 5.8e-40 136.6 0.0 1.2e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEP09105.1 - 3e-26 92.1 2.1 7.8e-26 90.8 0.5 2.3 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEP09105.1 - 1.2e-10 40.7 0.9 2.4e-10 39.7 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEP09105.1 - 1.1e-05 25.6 0.2 4.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PRP21_like_P PF12230.3 CEP09106.1 - 4.6e-63 212.7 11.9 1e-62 211.6 8.3 1.6 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CEP09106.1 - 2.4e-30 103.9 2.8 6.6e-17 60.9 0.1 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 CEP09106.1 - 2.8e-11 42.6 0.0 5.6e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CEP09106.1 - 0.12 12.6 0.3 0.79 10.0 0.0 2.3 2 1 0 2 2 2 0 Ubiquitin-like domain Mis14 PF08641.7 CEP09107.1 - 0.00054 20.0 3.7 0.0013 18.8 0.9 2.1 2 0 0 2 2 2 1 Kinetochore protein Mis14 like DUF3482 PF11981.3 CEP09107.1 - 0.036 13.3 0.5 0.66 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) IFT57 PF10498.4 CEP09107.1 - 0.06 12.0 3.8 0.33 9.6 2.6 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4404 PF14357.1 CEP09107.1 - 0.093 13.1 1.2 2.3 8.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) GCD14 PF08704.5 CEP09108.1 - 1.9e-89 299.3 0.0 2.3e-89 299.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CEP09108.1 - 9.9e-08 31.7 0.0 1.6e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP09108.1 - 2.5e-06 28.0 0.0 4.3e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEP09108.1 - 2.8e-05 23.7 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CEP09108.1 - 0.00053 19.9 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP09108.1 - 0.0017 17.7 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Gcd10p PF04189.8 CEP09108.1 - 0.054 12.6 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Gcd10p family Methyltransf_4 PF02390.12 CEP09108.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase vATP-synt_AC39 PF01992.11 CEP09109.1 - 5.8e-89 298.5 0.1 1.4e-88 297.2 0.1 1.5 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit Guanylate_cyc PF00211.15 CEP09110.1 - 6.6e-22 77.7 0.0 1.3e-21 76.7 0.0 1.6 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.20 CEP09111.1 - 1.5e-60 204.5 0.0 3.9e-60 203.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09111.1 - 1.3e-44 152.2 0.0 2.3e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP09111.1 - 4.6e-08 32.3 0.0 8.4e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF972 PF06156.8 CEP09111.1 - 0.095 13.0 12.1 0.075 13.3 3.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CEP09111.1 - 0.24 10.9 5.2 0.66 9.5 3.6 1.7 1 0 0 1 1 1 0 Septum formation initiator Metallophos PF00149.23 CEP09112.1 - 2.2e-40 138.1 0.2 4.1e-40 137.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BTB PF00651.26 CEP09114.1 - 4.2e-08 33.1 0.1 1.9e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain PRP1_N PF06424.7 CEP09115.1 - 1.2e-49 168.0 3.1 2.3e-49 167.1 2.1 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CEP09115.1 - 2.6e-37 123.8 13.9 0.00033 21.0 0.0 14.6 4 3 11 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.1 CEP09115.1 - 5.3e-29 100.3 5.7 7e-06 26.3 0.0 10.3 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 CEP09115.1 - 5.7e-24 84.2 2.7 0.00018 22.0 0.1 8.7 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 CEP09115.1 - 1.8e-17 62.7 6.4 1.4e-05 24.5 0.0 8.3 6 3 4 10 10 10 4 TPR repeat TPR_2 PF07719.12 CEP09115.1 - 5.3e-15 54.0 11.1 0.0061 16.3 0.0 12.3 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP09115.1 - 5.9e-13 47.5 5.7 0.00051 19.6 0.0 7.7 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEP09115.1 - 2.3e-10 39.8 0.9 0.9 9.9 0.0 9.6 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP09115.1 - 4.7e-10 39.2 6.2 1.7 9.3 0.0 9.6 10 1 0 10 10 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEP09115.1 - 4e-09 35.6 0.1 0.043 13.4 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP09115.1 - 2.5e-07 30.5 5.8 0.044 13.7 0.0 7.3 6 3 2 8 8 8 2 Tetratricopeptide repeat DUF3808 PF10300.4 CEP09115.1 - 0.00011 20.9 0.7 0.24 9.9 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_21 PF09976.4 CEP09115.1 - 0.00048 20.1 10.4 0.024 14.5 0.5 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.3 CEP09115.1 - 0.0009 18.1 9.8 0.015 14.0 0.0 5.0 4 1 2 6 6 6 1 NMDA receptor-regulated protein 1 Suf PF05843.9 CEP09115.1 - 0.0019 18.0 0.4 6.9 6.3 0.0 4.6 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_7 PF13176.1 CEP09115.1 - 0.025 14.3 4.0 13 5.8 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat rve PF00665.21 CEP09116.1 - 1.8e-10 40.9 0.1 1.5e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF4483 PF14825.1 CEP09116.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) rve PF00665.21 CEP09117.1 - 4.8e-19 68.6 0.0 8.4e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF845 PF05820.6 CEP09117.1 - 0.019 14.6 0.9 0.077 12.7 0.3 2.1 2 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF845) DDE_Tnp_IS240 PF13610.1 CEP09117.1 - 0.032 14.1 0.1 0.049 13.5 0.1 1.3 1 0 0 1 1 1 0 DDE domain Z1 PF10593.4 CEP09118.1 - 0.53 9.4 4.6 0.26 10.4 0.7 2.2 2 0 0 2 2 2 0 Z1 domain TrbM PF07424.6 CEP09118.1 - 5.8 6.8 7.6 0.29 11.0 0.8 2.1 3 0 0 3 3 3 0 TrbM TcdB_N PF12918.2 CEP09119.1 - 1.9 8.6 15.6 3.7 7.7 0.2 4.8 5 0 0 5 5 5 0 TcdB toxin N-terminal helical domain Prefoldin_3 PF13758.1 CEP09119.1 - 3.1 7.6 16.3 0.3 10.9 4.3 3.4 2 2 0 2 2 2 0 Prefoldin subunit Cyt-b5 PF00173.23 CEP09121.1 - 8.5e-10 38.3 0.1 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phage_integrase PF00589.17 CEP09124.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family PIP5K PF01504.13 CEP09125.1 - 2.5e-60 203.7 7.5 1e-59 201.6 1.6 2.8 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CEP09125.1 - 1.5e-16 60.0 0.0 4.4e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family RabGAP-TBC PF00566.13 CEP09126.1 - 7e-55 185.8 0.8 2e-54 184.3 0.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Gln-synt_C PF00120.19 CEP09127.1 - 6e-61 205.8 0.0 7.3e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CEP09127.1 - 4e-18 64.7 0.0 6.6e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RVT_1 PF00078.22 CEP09128.1 - 0.00026 20.4 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP09128.1 - 0.0029 17.8 2.6 0.0042 17.3 0.6 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.1 CEP09129.1 - 6.7e-07 28.9 0.5 1.7e-06 27.6 0.3 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 CEP09129.1 - 4.3e-06 26.2 0.1 1.3e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_4 PF14392.1 CEP09129.1 - 5e-05 22.8 3.1 0.00072 19.1 0.1 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 CEP09129.1 - 0.0001 22.0 12.5 0.0011 18.7 1.1 2.6 2 0 0 2 2 2 2 Zinc knuckle Exo_endo_phos PF03372.18 CEP09129.1 - 0.00061 19.8 1.3 0.00094 19.1 0.4 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Amidohydro_5 PF13594.1 CEP09133.1 - 5.6e-12 45.3 0.5 1.3e-11 44.1 0.4 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CEP09133.1 - 4.6e-05 23.6 0.9 9.6e-05 22.5 0.1 2.0 3 0 0 3 3 3 1 Amidohydrolase Tenui_NCP PF04876.7 CEP09134.1 - 0.057 12.9 0.1 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein Cucumo_2B PF03263.8 CEP09137.1 - 0.027 14.7 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 Cucumovirus protein 2B Maff2 PF12750.2 CEP09138.1 - 0.035 13.6 0.2 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 Maff2 family DUF742 PF05331.6 CEP09138.1 - 0.071 12.7 0.3 0.071 12.7 0.2 3.4 3 2 1 4 4 4 0 Protein of unknown function (DUF742) Helitron_like_N PF14214.1 CEP09140.1 - 1.9e-33 115.7 0.1 2.4e-33 115.4 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 CEP09140.1 - 0.016 14.7 0.0 0.05 13.1 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3296) zf-RVT PF13966.1 CEP09144.1 - 0.00054 20.2 0.5 0.00099 19.3 0.3 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 CEP09146.1 - 3.1e-09 36.5 0.0 4.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAM2 PF07145.10 CEP09147.1 - 0.025 14.0 0.2 0.059 12.8 0.1 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-RVT PF13966.1 CEP09149.1 - 0.00033 20.9 0.4 0.00071 19.8 0.3 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Phytochelatin PF05023.9 CEP09151.1 - 6e-43 146.3 0.0 7.6e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Velvet PF11754.3 CEP09152.1 - 1e-44 152.6 1.5 1.6e-42 145.4 0.2 2.7 2 1 0 2 2 2 1 Velvet factor MFS_1 PF07690.11 CEP09154.1 - 5.3e-11 41.8 25.9 1.5e-08 33.7 9.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CEP09154.1 - 0.15 11.8 7.2 0.24 11.1 0.1 3.3 3 0 0 3 3 3 0 MFS_1 like family Ribosomal_L13 PF00572.13 CEP09155.1 - 3.8e-24 85.1 0.0 6.9e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 MRP-S33 PF08293.6 CEP09156.1 - 2.1e-27 94.8 0.1 2.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 GATA PF00320.22 CEP09157.1 - 8.1e-14 50.6 6.3 8.1e-14 50.6 4.4 2.1 2 0 0 2 2 2 1 GATA zinc finger Cut8_M PF14483.1 CEP09158.1 - 0.0027 17.4 0.1 0.0042 16.8 0.1 1.3 1 0 0 1 1 1 1 Cut8 dimerisation domain CSTF2_hinge PF14327.1 CEP09158.1 - 0.09 12.8 0.1 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 EF-hand_1 PF00036.27 CEP09159.1 - 2.4e-07 29.5 3.0 2.6e-06 26.3 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 CEP09159.1 - 3.7e-07 30.1 1.9 0.0021 18.1 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP09159.1 - 1.8e-06 27.3 0.2 0.083 12.8 0.0 3.4 3 1 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 CEP09159.1 - 0.00013 21.5 1.1 0.003 17.1 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CEP09159.1 - 0.0035 16.6 0.0 0.013 14.7 0.0 2.0 2 0 0 2 2 2 1 EF hand CheD PF03975.8 CEP09159.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Ribosomal_L22 PF00237.14 CEP09160.1 - 2.3e-34 117.4 0.1 3e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S6e PF01092.14 CEP09161.1 - 7.4e-60 200.1 0.3 1.3e-59 199.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e IF4E PF01652.13 CEP09162.1 - 7.1e-57 191.5 2.2 8.7e-57 191.2 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Fungal_trans PF04082.13 CEP09163.1 - 3.4e-16 58.8 0.1 3.4e-16 58.8 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP09163.1 - 0.0083 16.0 11.8 0.019 14.8 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Eno-Rase_FAD_bd PF07055.7 CEP09164.1 - 0.17 11.8 0.2 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain V-ATPase_H_N PF03224.9 CEP09165.1 - 2.5e-77 260.0 3.6 1.5e-76 257.5 2.2 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CEP09165.1 - 1.8e-36 124.6 3.3 1.5e-35 121.7 0.0 2.8 2 1 1 3 3 3 1 V-ATPase subunit H Arm PF00514.18 CEP09165.1 - 0.00075 19.2 1.4 1.8 8.5 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat ParcG PF10274.4 CEP09165.1 - 0.026 14.4 1.0 0.11 12.3 0.2 2.3 1 1 2 3 3 3 0 Parkin co-regulated protein HEAT_2 PF13646.1 CEP09165.1 - 0.032 14.5 0.0 0.29 11.4 0.0 2.5 3 0 0 3 3 3 0 HEAT repeats DUF2985 PF11204.3 CEP09165.1 - 0.034 13.8 0.1 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Aminotran_1_2 PF00155.16 CEP09166.1 - 1.5e-43 149.1 0.0 2e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEP09166.1 - 0.18 10.9 0.0 0.34 10.0 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase NDUF_B12 PF08122.7 CEP09167.1 - 6.7e-20 70.5 0.7 7.8e-20 70.3 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family YqcI_YcgG PF08892.6 CEP09170.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 YqcI/YcgG family DUF3772 PF12607.3 CEP09170.1 - 1.3 8.7 4.6 0.28 10.8 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Peptidase_C78 PF07910.8 CEP09171.1 - 2.1e-54 183.9 0.1 3.7e-54 183.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C78 AcetylCoA_hydro PF02550.10 CEP09172.1 - 1e-50 172.2 0.0 1.4e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 CEP09172.1 - 1.4e-38 132.0 0.0 2.1e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AA_permease_2 PF13520.1 CEP09173.1 - 1.7e-56 191.5 56.1 2.2e-56 191.2 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP09173.1 - 2.2e-29 102.1 45.4 2.9e-29 101.7 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 CEP09174.1 - 7.6e-52 176.0 0.0 1.1e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09174.1 - 2.5e-19 69.3 0.0 9.6e-19 67.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP09174.1 - 9e-08 31.4 0.0 1.9e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CEP09174.1 - 5.5e-05 22.3 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CEP09174.1 - 0.00061 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CEP09174.1 - 0.0053 16.5 1.0 0.007 16.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2203 PF09969.4 CEP09174.1 - 0.29 11.3 1.8 6.4 7.0 0.7 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) SPOB_ab PF14682.1 CEP09175.1 - 0.04 13.6 0.3 6.7 6.5 0.1 2.1 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal DDE_1 PF03184.14 CEP09176.1 - 9.2e-20 70.7 0.4 1.1e-19 70.4 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 CEP09176.1 - 0.041 13.6 0.1 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 DDE superfamily endonuclease DDE_1 PF03184.14 CEP09177.1 - 9.2e-12 44.5 0.0 1.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MIF4G PF02854.14 CEP09178.1 - 6e-47 159.7 2.4 1.3e-46 158.7 1.7 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 CEP09178.1 - 2.9e-16 59.1 1.5 2.9e-16 59.1 1.0 2.0 2 0 0 2 2 2 1 MA3 domain eIF_4G1 PF12152.3 CEP09178.1 - 4.5e-07 29.6 0.0 1.5e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 CDT1 PF08839.6 CEP09179.1 - 2.9e-07 30.5 0.0 2.9e-07 30.5 0.0 2.7 2 1 0 2 2 2 1 DNA replication factor CDT1 like DUF966 PF06136.8 CEP09179.1 - 0.78 9.0 19.5 1.4 8.3 13.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LicD PF04991.8 CEP09179.1 - 0.98 9.4 8.1 0.74 9.8 3.7 2.0 2 0 0 2 2 2 0 LicD family Mab-21 PF03281.9 CEP09179.1 - 8.8 5.3 11.7 7.9 5.5 7.0 1.8 1 1 1 2 2 2 0 Mab-21 protein Peptidase_M22 PF00814.20 CEP09180.1 - 2.6e-73 246.7 0.0 5.5e-73 245.7 0.0 1.5 1 1 0 1 1 1 1 Glycoprotease family NUC129 PF08157.6 CEP09181.1 - 0.008 16.0 0.1 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 NUC129 domain Pkinase PF00069.20 CEP09182.1 - 6.2e-73 245.1 0.0 7.6e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09182.1 - 1.9e-36 125.4 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP09182.1 - 1e-06 27.9 0.0 1.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CEP09182.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 SBBP PF06739.6 CEP09183.1 - 0.011 15.5 0.0 0.072 12.8 0.0 2.4 2 0 0 2 2 2 0 Beta-propeller repeat Fasciclin PF02469.17 CEP09184.1 - 5.2e-66 220.4 5.8 2.2e-21 76.1 0.3 5.5 5 0 0 5 5 5 5 Fasciclin domain MFS_1 PF07690.11 CEP09184.1 - 1.1e-26 93.4 36.9 1.1e-26 93.4 25.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Maff2 PF12750.2 CEP09184.1 - 0.03 13.8 0.1 0.03 13.8 0.0 2.9 3 0 0 3 3 3 0 Maff2 family Chorion_3 PF05387.6 CEP09184.1 - 0.048 13.1 0.7 0.093 12.1 0.5 1.4 1 0 0 1 1 1 0 Chorion family 3 zf-Nse PF11789.3 CEP09185.1 - 1.8e-15 56.1 1.0 3.5e-15 55.2 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CEP09185.1 - 9.2e-05 22.0 0.8 0.00021 20.9 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CEP09185.1 - 0.0042 16.9 0.5 0.0079 16.0 0.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 CEP09185.1 - 0.033 13.7 1.5 0.059 12.8 1.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Cep57_CLD PF14073.1 CEP09185.1 - 0.033 14.0 0.8 0.052 13.3 0.5 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 zf-C3HC4 PF00097.20 CEP09185.1 - 0.095 12.3 0.5 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DAGK_acc PF00609.14 CEP09186.1 - 3e-18 66.4 0.0 5e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CEP09186.1 - 6.9e-14 51.3 0.0 2e-11 43.4 0.0 2.6 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain Usp PF00582.21 CEP09187.1 - 4.3e-23 82.0 0.1 5.9e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family THF_DHG_CYH PF00763.18 CEP09189.1 - 0.042 13.8 0.1 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DNA_ligase_A_N PF04675.9 CEP09189.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA ligase N terminus DDE_Tnp_1_7 PF13843.1 CEP09191.1 - 7.6e-22 77.8 0.0 9.4e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 rve PF00665.21 CEP09192.1 - 3e-21 75.7 0.0 4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Host_attach PF10116.4 CEP09194.1 - 0.44 10.7 4.3 8.8 6.5 0.2 2.3 2 0 0 2 2 2 0 Protein required for attachment to host cells zf-C2H2_2 PF12756.2 CEP09194.1 - 3.7 7.7 7.8 1.2 9.2 0.9 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RVT_1 PF00078.22 CEP09196.1 - 6.6e-24 84.4 0.0 8.5e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4123 PF13503.1 CEP09196.1 - 0.1 12.6 0.2 0.75 9.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4123) rve PF00665.21 CEP09198.1 - 4.3e-14 52.6 0.0 1.3e-10 41.4 0.0 2.3 1 1 1 2 2 2 2 Integrase core domain rve_3 PF13683.1 CEP09198.1 - 0.00027 20.4 0.1 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain NMT_C PF02799.10 CEP09199.1 - 4e-76 254.6 1.3 4e-76 254.6 0.9 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 CEP09199.1 - 5.7e-71 237.3 0.0 1.1e-70 236.4 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain HIG_1_N PF04588.8 CEP09200.1 - 1.3e-05 24.8 2.1 1.3e-05 24.8 1.4 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region ENOD93 PF03386.9 CEP09200.1 - 0.0089 15.7 0.1 0.02 14.5 0.0 1.6 2 0 0 2 2 2 1 Early nodulin 93 ENOD93 protein DUF543 PF04418.7 CEP09200.1 - 0.024 14.5 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Romo1 PF10247.4 CEP09200.1 - 0.031 14.4 0.2 0.061 13.5 0.1 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 FAD_oxidored PF12831.2 CEP09200.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF2613 PF11021.3 CEP09200.1 - 0.66 9.7 2.9 14 5.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) WD40 PF00400.27 CEP09201.1 - 1.1e-39 132.9 10.6 4.3e-09 35.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 CEP09201.1 - 5.3e-33 112.5 1.5 1.1e-32 111.6 1.0 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 CEP09201.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain DUF3450 PF11932.3 CEP09201.1 - 0.012 14.9 1.8 0.025 13.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) WEMBL PF05701.6 CEP09201.1 - 0.021 13.2 1.2 0.03 12.8 0.8 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF1631 PF07793.6 CEP09201.1 - 0.027 12.6 2.2 0.04 12.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-Nse PF11789.3 CEP09201.1 - 0.094 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_60s PF00428.14 CEP09201.1 - 1.7 9.1 10.4 6 7.3 7.2 2.1 1 1 0 1 1 1 0 60s Acidic ribosomal protein Metal_resist PF13801.1 CEP09201.1 - 5.1 7.1 10.4 4.7 7.2 5.3 1.9 1 1 1 2 2 2 0 Heavy-metal resistance Amino_oxidase PF01593.19 CEP09203.1 - 1.4e-13 50.7 0.0 1.2e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEP09203.1 - 8.2e-10 38.5 0.0 2.3e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEP09203.1 - 8.4e-08 31.5 0.0 5.8e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CEP09203.1 - 0.0011 18.0 0.7 0.004 16.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 CEP09203.1 - 0.011 16.0 0.1 0.087 13.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP09203.1 - 0.015 15.3 0.0 0.072 13.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP09203.1 - 0.021 14.5 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 CEP09203.1 - 0.033 12.8 0.1 0.049 12.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 CEP09203.1 - 0.038 13.8 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CEP09203.1 - 0.096 11.5 0.2 0.58 8.9 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-H2C2_2 PF13465.1 CEP09204.1 - 2.9e-13 49.3 18.1 2.9e-07 30.4 2.7 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP09204.1 - 5.6e-09 35.8 16.7 1.4e-05 25.1 2.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP09204.1 - 2.3e-08 33.8 10.6 0.0011 19.1 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CEP09204.1 - 0.067 13.3 3.5 0.15 12.2 2.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding RPAP2_Rtr1 PF04181.8 CEP09204.1 - 0.094 12.8 0.3 0.2 11.7 0.1 1.6 1 1 0 1 1 1 0 Rtr1/RPAP2 family zf-C2H2_jaz PF12171.3 CEP09204.1 - 0.13 12.4 2.2 1.3 9.2 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ThiF PF00899.16 CEP09205.1 - 8e-28 96.9 0.0 1.6e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CEP09205.1 - 0.0034 17.4 0.0 0.048 13.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Evr1_Alr PF04777.8 CEP09206.1 - 5.7e-28 96.6 4.8 5.7e-28 96.6 3.3 2.4 2 0 0 2 2 2 1 Erv1 / Alr family Zn_clus PF00172.13 CEP09207.1 - 0.0039 17.0 8.5 0.0089 15.9 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T4SS PF07996.6 CEP09207.1 - 0.029 14.2 0.1 0.073 12.9 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion system proteins dCMP_cyt_deam_1 PF00383.17 CEP09208.1 - 2.2e-12 46.5 0.0 4.1e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CEP09208.1 - 0.00039 20.2 0.4 0.0027 17.5 0.3 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase DIOX_N PF14226.1 CEP09209.1 - 6.9e-20 71.7 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CEP09209.1 - 1.6e-15 57.1 0.0 3.8e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SRPRB PF09439.5 CEP09209.1 - 0.018 14.2 0.5 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DNA_pol_lambd_f PF10391.4 CEP09209.1 - 0.024 14.1 0.0 6.9 6.3 0.0 2.7 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda adh_short PF00106.20 CEP09210.1 - 6.4e-25 87.9 1.6 9.4e-25 87.4 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP09210.1 - 2.1e-15 57.1 0.7 2.5e-15 56.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP09210.1 - 5.7e-08 32.6 0.9 5.2e-07 29.5 0.4 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CEP09210.1 - 6.5e-06 25.7 0.4 1.8e-05 24.2 0.2 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEP09210.1 - 0.003 17.5 0.3 0.0043 17.0 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CEP09210.1 - 0.0042 16.0 0.1 0.0061 15.4 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain ADH_zinc_N PF00107.21 CEP09210.1 - 0.0087 15.6 0.9 0.013 15.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3561 PF12084.3 CEP09210.1 - 0.081 12.7 0.2 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) TauD PF02668.11 CEP09212.1 - 3e-26 92.6 0.0 3.8e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 CEP09212.1 - 0.0035 16.2 0.0 0.0054 15.6 0.0 1.2 1 0 0 1 1 1 1 CsiD WD40 PF00400.27 CEP09213.1 - 8.4e-93 301.2 24.2 3.3e-15 55.3 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CEP09213.1 - 2.1e-14 53.2 0.0 3.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CEP09213.1 - 6.7e-10 37.7 6.6 0.009 14.1 0.0 5.6 1 1 4 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.6 CEP09213.1 - 2e-09 37.4 0.9 0.0027 17.4 0.0 3.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CEP09213.1 - 3.3e-07 29.6 1.2 0.088 11.8 0.0 4.4 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 CEP09213.1 - 2.3e-05 23.9 1.6 0.99 9.1 0.0 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 CEP09213.1 - 3.7e-05 23.2 0.1 0.052 12.9 0.0 3.1 2 1 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain IKI3 PF04762.7 CEP09213.1 - 0.0013 16.7 1.3 0.37 8.5 0.0 2.5 2 1 0 2 2 2 2 IKI3 family BBS2_Mid PF14783.1 CEP09213.1 - 0.0028 17.4 0.0 10 5.9 0.0 4.0 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF3312 PF11768.3 CEP09213.1 - 0.0032 15.7 0.0 0.73 7.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 CEP09213.1 - 0.026 13.2 4.4 9.8 4.7 0.0 3.6 2 1 0 2 2 2 0 Nup133 N terminal like Proteasome_A_N PF10584.4 CEP09213.1 - 0.22 10.8 3.2 1.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Dus PF01207.12 CEP09214.1 - 1.1e-78 264.2 0.0 1.5e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.12 CEP09214.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 SOR/SNZ family His_biosynth PF00977.16 CEP09214.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.9 CEP09214.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 CEP09214.1 - 0.073 12.1 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase PEP_mutase PF13714.1 CEP09214.1 - 0.096 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DUF4137 PF13593.1 CEP09215.1 - 5.1e-87 291.8 21.0 6.3e-87 291.5 14.6 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 CEP09215.1 - 2.7e-10 39.9 12.4 2.7e-10 39.9 8.6 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family Synaptobrevin PF00957.16 CEP09215.1 - 0.0058 16.2 0.1 0.0058 16.2 0.1 2.4 4 0 0 4 4 4 1 Synaptobrevin COX6B PF02297.12 CEP09216.1 - 5.3e-24 84.0 1.5 6.1e-24 83.8 1.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 CEP09216.1 - 0.0056 16.6 1.6 0.039 14.0 1.1 1.9 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 CEP09216.1 - 0.71 9.7 3.3 0.75 9.6 0.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) OTU PF02338.14 CEP09217.1 - 2.7e-19 69.9 1.0 4.9e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CEP09217.1 - 1.8e-05 24.1 1.2 9.4e-05 21.8 0.0 2.6 2 1 0 2 2 2 1 Peptidase C65 Otubain PMSR PF01625.16 CEP09218.1 - 2.7e-57 193.0 0.8 3.3e-57 192.7 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KaiA PF07688.7 CEP09218.1 - 0.12 11.6 0.1 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 KaiA domain TFIIIC_delta PF12657.2 CEP09219.1 - 4e-12 46.1 0.1 1e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term DUF1479 PF07350.7 CEP09221.1 - 1.4e-69 234.5 0.4 1.9e-66 224.2 0.3 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 CEP09221.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PCI PF01399.22 CEP09222.1 - 1.7e-14 53.9 0.3 6.2e-14 52.1 0.0 2.1 2 1 0 2 2 2 1 PCI domain tRNA-synt_1c PF00749.16 CEP09222.1 - 0.086 11.4 0.6 0.13 10.8 0.4 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain TSA PF03249.8 CEP09223.1 - 0.098 11.1 7.3 0.3 9.5 1.0 2.2 2 0 0 2 2 2 0 Type specific antigen Pex14_N PF04695.8 CEP09223.1 - 4.5 7.3 8.8 0.34 10.9 1.2 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tubulin_3 PF14881.1 CEP09224.1 - 3.6e-47 160.1 0.0 6.6e-47 159.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CEP09224.1 - 9.6e-38 128.7 0.4 2.8e-37 127.2 0.1 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 CEP09224.1 - 7.2e-10 39.0 0.0 6.6e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Cir_N PF10197.4 CEP09225.1 - 4.9e-07 29.6 3.1 4.9e-07 29.6 2.1 4.1 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR NDT80_PhoG PF05224.7 CEP09226.1 - 4e-25 88.9 0.3 4e-25 88.9 0.2 4.1 3 2 0 3 3 3 1 NDT80 / PhoG like DNA-binding family DUF4407 PF14362.1 CEP09226.1 - 8.5 5.2 7.5 13 4.5 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AFG1_ATPase PF03969.11 CEP09227.1 - 3.9e-107 358.1 1.4 1.6e-101 339.7 0.3 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 CEP09227.1 - 0.00012 22.1 0.1 0.021 14.7 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CEP09227.1 - 0.00068 19.7 0.0 0.0027 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CEP09227.1 - 0.034 14.3 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CEP09227.1 - 0.077 12.6 0.2 0.58 9.8 0.0 2.4 2 1 0 2 2 2 0 NACHT domain ARID PF01388.16 CEP09228.1 - 6.4e-21 74.0 0.0 1.5e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3453 PF11935.3 CEP09228.1 - 0.00086 18.7 0.4 0.0018 17.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) GATA PF00320.22 CEP09229.1 - 5.1e-16 57.7 4.7 5.1e-16 57.7 3.3 2.0 1 1 1 2 2 2 1 GATA zinc finger Cytochrom_c3_2 PF14537.1 CEP09229.1 - 0.014 15.7 0.2 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 CEP09229.1 - 0.052 13.1 0.3 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 Cytochrome c7 E2R135 PF11570.3 CEP09229.1 - 0.061 13.4 3.1 0.12 12.4 2.1 1.5 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF3742 PF12553.3 CEP09229.1 - 0.095 13.1 0.2 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) DZR PF12773.2 CEP09229.1 - 0.3 10.9 2.8 1.2 8.9 1.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon tRNA-synt_2b PF00587.20 CEP09230.1 - 2e-14 53.5 0.0 3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.10 CEP09230.1 - 5.7e-14 52.0 0.4 1.1e-13 51.1 0.3 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain CENP-O PF09496.5 CEP09232.1 - 1e-11 44.8 2.9 1.2e-11 44.7 0.7 2.0 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DUF496 PF04363.7 CEP09232.1 - 0.2 11.4 3.7 0.28 11.0 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF496) VHS PF00790.14 CEP09233.1 - 4.4e-32 110.6 0.1 8.6e-32 109.7 0.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 CEP09233.1 - 4.7e-18 64.3 2.4 6.7e-17 60.6 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CEP09233.1 - 5.8e-17 61.0 0.3 1.4e-16 59.7 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP09233.1 - 1.2e-13 50.3 0.2 5.2e-13 48.2 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.9 CEP09233.1 - 0.0012 18.7 1.3 0.0012 18.7 0.9 2.2 2 0 0 2 2 2 1 GAT domain UIM PF02809.15 CEP09233.1 - 0.0018 17.7 3.0 0.005 16.2 2.1 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Trypsin PF00089.21 CEP09234.1 - 2e-21 76.5 0.0 1.6e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.1 CEP09234.1 - 0.0086 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain GshA PF08886.6 CEP09234.1 - 0.071 11.3 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase YqzE PF14038.1 CEP09235.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 YqzE-like protein DDE_3 PF13358.1 CEP09236.1 - 8.9e-17 61.1 0.0 4.1e-16 59.0 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP09236.1 - 3.9e-08 33.4 0.1 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP09236.1 - 8.5e-07 28.8 0.3 4e-05 23.5 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP09236.1 - 4.2e-06 27.4 0.0 1.8e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 CEP09236.1 - 1.7e-05 24.3 1.3 0.00036 20.0 0.1 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CEP09236.1 - 0.0046 16.1 0.3 0.015 14.4 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Terminase_5 PF06056.7 CEP09236.1 - 0.016 14.7 0.3 0.092 12.3 0.0 2.1 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_17 PF12728.2 CEP09236.1 - 0.016 15.4 0.1 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 CEP09236.1 - 0.032 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Transposase ProRS-C_1 PF09180.6 CEP09237.1 - 7.8e-10 38.5 0.0 7.8e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 CEP09237.1 - 2.3e-05 24.2 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Dsh_C PF12316.3 CEP09238.1 - 2.7 8.0 5.9 3.1 7.8 4.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal rve PF00665.21 CEP09240.1 - 5.4e-11 42.6 0.0 1.5e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Orthopox_A5L PF06193.6 CEP09242.1 - 0.12 12.2 0.2 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like HTH_23 PF13384.1 CEP09243.1 - 1.1e-06 28.1 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 CEP09243.1 - 0.00043 20.1 0.4 0.00064 19.6 0.1 1.5 1 1 0 1 1 1 1 Transposase DUF1804 PF08822.6 CEP09243.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) MerR_1 PF13411.1 CEP09243.1 - 0.067 12.9 2.2 0.22 11.2 0.0 2.5 2 1 1 3 3 3 0 MerR HTH family regulatory protein Phage_terminase PF10668.4 CEP09243.1 - 0.091 12.5 0.7 0.17 11.6 0.5 1.6 1 1 0 1 1 1 0 Phage terminase small subunit Pkinase PF00069.20 CEP09244.1 - 9e-79 264.2 0.1 2.2e-26 92.5 0.0 4.9 4 1 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09244.1 - 3.1e-44 150.9 0.0 2.4e-16 59.5 0.0 4.5 4 0 0 4 4 4 4 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 CEP09244.1 - 2.3e-29 102.3 6.5 2.3e-29 102.3 4.5 3.1 3 1 0 3 3 3 1 Anticodon binding domain of tRNAs RWD PF05773.17 CEP09244.1 - 4.5e-17 61.9 0.1 1.3e-16 60.5 0.1 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 CEP09244.1 - 1e-13 51.0 0.0 2.6e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.18 CEP09244.1 - 1.9e-05 24.5 0.0 0.00039 20.2 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP09244.1 - 0.00066 18.7 0.0 0.14 11.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Peptidase_M13 PF01431.16 CEP09245.1 - 5.1e-51 172.7 0.1 8.3e-51 172.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 CEP09245.1 - 4.1e-25 88.6 1.2 4.7e-24 85.1 0.8 2.1 1 1 0 1 1 1 1 Peptidase family M13 DALR_1 PF05746.10 CEP09245.1 - 0.04 13.8 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 DALR anticodon binding domain adh_short PF00106.20 CEP09246.1 - 4.8e-16 59.1 0.0 7.3e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEP09246.1 - 5.6e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 CEP09246.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 CEP09246.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CEP09246.1 - 0.0073 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 CEP09246.1 - 0.031 14.5 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 CEP09246.1 - 0.054 13.3 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 CEP09246.1 - 0.071 13.1 0.1 0.14 12.1 0.1 1.9 1 1 0 1 1 1 0 NADH(P)-binding TYW3 PF02676.9 CEP09248.1 - 1.5e-21 76.4 0.0 1.8e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF3584 PF12128.3 CEP09249.1 - 0.09 10.0 10.3 0.12 9.6 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Arrestin_N PF00339.24 CEP09249.1 - 0.16 11.7 3.9 0.32 10.8 2.7 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain PcfK PF14058.1 CEP09249.1 - 0.99 9.5 12.1 38 4.3 8.8 2.3 2 0 0 2 2 2 0 PcfK-like protein DUF2229 PF09989.4 CEP09249.1 - 1.6 8.1 6.6 0.99 8.8 3.1 1.6 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) CPSF100_C PF13299.1 CEP09249.1 - 1.9 8.6 6.6 1 9.5 1.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3464 PF11947.3 CEP09249.1 - 4 6.8 9.5 8.4 5.8 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Ank_2 PF12796.2 CEP09250.1 - 5.7e-48 161.2 6.2 5.7e-23 81.0 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEP09250.1 - 3.4e-43 143.3 10.2 6.4e-09 35.1 0.0 5.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 CEP09250.1 - 2.2e-39 132.5 8.9 1e-09 38.3 0.1 5.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP09250.1 - 6.8e-38 128.3 10.8 2.8e-14 53.1 0.1 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP09250.1 - 1.2e-36 121.0 5.2 8.5e-07 28.6 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat HEM4 PF02602.10 CEP09250.1 - 0.053 12.7 0.0 3 7.0 0.0 2.1 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD DUF3734 PF12536.3 CEP09250.1 - 0.098 12.7 0.5 17 5.5 0.2 2.9 1 1 3 4 4 4 0 Patatin phospholipase zf-RING_2 PF13639.1 CEP09252.1 - 1.1e-14 53.9 5.4 2e-14 53.1 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP09252.1 - 4.3e-10 39.5 2.8 4.3e-10 39.5 2.0 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CEP09252.1 - 1.2e-08 34.5 4.0 1.9e-08 33.8 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEP09252.1 - 1.4e-08 34.2 4.8 2.4e-08 33.4 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP09252.1 - 7.2e-08 32.3 4.5 1.2e-07 31.6 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP09252.1 - 2.3e-06 27.1 2.4 3.8e-06 26.4 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEP09252.1 - 1.4e-05 24.7 1.3 3.5e-05 23.5 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger K167R PF08065.7 CEP09252.1 - 0.0035 17.4 6.2 0.0035 17.4 4.3 2.2 2 0 0 2 2 2 1 K167R (NUC007) repeat zf-RING_4 PF14570.1 CEP09252.1 - 0.005 16.3 4.1 0.008 15.7 2.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CEP09252.1 - 0.011 15.2 5.6 0.049 13.1 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 CEP09252.1 - 0.014 15.4 6.7 0.026 14.5 4.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 CEP09252.1 - 0.018 14.7 2.1 0.018 14.7 1.4 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.6 CEP09252.1 - 0.037 14.0 5.0 0.076 13.0 3.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 CEP09252.1 - 0.55 10.1 5.4 7.6 6.5 3.8 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING REV PF00424.13 CEP09252.1 - 1.1 9.2 15.9 2.6 8.0 2.8 2.7 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PHD PF00628.24 CEP09252.1 - 1.4 8.6 6.2 2.6 7.7 4.3 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 CEP09252.1 - 1.5 8.8 4.6 4.2 7.3 3.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain TrbL PF04610.9 CEP09252.1 - 2.6 7.7 4.2 5.6 6.5 1.1 2.1 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Response_reg PF00072.19 CEP09254.1 - 2.7e-21 75.6 0.1 6.8e-14 51.8 0.0 2.9 2 0 0 2 2 2 2 Response regulator receiver domain Ribosomal_S8e PF01201.17 CEP09255.1 - 1.8e-34 118.7 10.0 1.1e-33 116.1 6.9 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e BTB_2 PF02214.17 CEP09255.1 - 1.6e-19 69.9 0.0 6.9e-19 67.8 0.0 2.2 1 0 0 1 1 1 1 BTB/POZ domain tRNA-synt_1 PF00133.17 CEP09256.1 - 8.8e-142 473.1 0.8 1.1e-141 472.8 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CEP09256.1 - 3.9e-31 107.8 3.7 8.4e-31 106.8 2.6 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CEP09256.1 - 1.8e-06 26.8 1.9 0.0068 15.1 0.4 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 CEP09256.1 - 9.5e-06 25.1 4.9 1.9e-05 24.1 3.4 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 CEP09256.1 - 2.1e-05 23.9 0.0 4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 DZR PF12773.2 CEP09256.1 - 1.2 9.0 3.6 2.4 8.0 2.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon MFS_1 PF07690.11 CEP09257.1 - 2.6e-33 115.2 43.6 1.2e-21 76.8 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP09257.1 - 2.4e-07 29.7 38.9 2.2e-05 23.2 26.5 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter SMC_N PF02463.14 CEP09258.1 - 3.6e-16 59.0 27.8 3.4e-12 46.0 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEP09258.1 - 1.3e-10 41.9 35.7 1.3e-10 41.9 24.8 5.4 2 2 1 3 3 2 1 AAA domain AAA_29 PF13555.1 CEP09258.1 - 2.9e-05 23.5 0.0 0.00013 21.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain GAS PF13851.1 CEP09258.1 - 0.00028 20.1 22.4 0.00028 20.1 15.5 6.4 3 2 2 5 5 4 1 Growth-arrest specific micro-tubule binding AAA_21 PF13304.1 CEP09258.1 - 0.00035 20.6 2.9 0.00035 20.6 2.0 3.7 2 2 2 4 4 4 1 AAA domain BLOC1_2 PF10046.4 CEP09258.1 - 0.0095 16.0 1.3 0.0095 16.0 0.9 7.8 3 2 3 8 8 8 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_19 PF13245.1 CEP09258.1 - 0.12 12.1 0.2 0.35 10.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_13 PF13166.1 CEP09258.1 - 0.14 10.6 0.0 0.14 10.6 0.0 4.4 3 1 1 4 4 4 0 AAA domain AAA_25 PF13481.1 CEP09258.1 - 0.15 11.4 0.0 0.15 11.4 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_17 PF13207.1 CEP09258.1 - 0.55 11.0 0.0 0.55 11.0 0.0 3.8 4 1 0 4 4 4 0 AAA domain YgbB PF02542.11 CEP09258.1 - 4.1 7.2 6.3 0.46 10.2 0.2 2.5 3 0 0 3 3 3 0 YgbB family Reo_sigmaC PF04582.7 CEP09258.1 - 9.7 5.2 11.6 0.99 8.5 0.2 3.3 4 0 0 4 4 4 0 Reovirus sigma C capsid protein Peptidase_S26 PF10502.4 CEP09261.1 - 0.0013 18.2 0.0 0.19 11.2 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 CEP09261.1 - 0.0031 17.1 0.1 0.0057 16.2 0.1 1.6 1 1 0 1 1 1 1 Peptidase S24-like LRR_4 PF12799.2 CEP09262.1 - 5.6e-25 86.4 12.5 3e-09 36.2 0.2 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP09262.1 - 1.1e-19 69.8 15.4 5.3e-10 38.9 3.0 3.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CEP09262.1 - 3.3e-15 53.7 21.0 0.029 14.3 0.0 7.8 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 CEP09262.1 - 1.3e-12 45.7 13.4 0.78 10.1 0.1 7.7 6 1 1 7 7 7 4 Leucine rich repeat Ribosomal_L9_C PF03948.9 CEP09262.1 - 1e-11 44.7 0.6 3e-11 43.2 0.4 1.9 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.14 CEP09262.1 - 2.9e-10 39.2 0.1 5.7e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain LRR_6 PF13516.1 CEP09262.1 - 4.4e-09 35.4 14.2 0.27 11.4 0.1 7.6 6 1 1 7 7 7 3 Leucine Rich repeat LRR_3 PF07725.7 CEP09262.1 - 0.84 9.5 3.8 3.9 7.4 0.3 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat TMPIT PF07851.8 CEP09263.1 - 0.013 14.5 0.6 0.019 14.0 0.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mito_carr PF00153.22 CEP09265.1 - 3.3e-27 94.0 5.7 1.5e-11 43.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec10 PF07393.6 CEP09266.1 - 5e-111 372.0 3.4 6.3e-111 371.7 2.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 CEP09266.1 - 1.7e-07 30.8 0.1 3.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP09266.1 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Cyclin PF08613.6 CEP09267.1 - 3.1e-37 128.2 0.8 4.4e-37 127.7 0.5 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP09267.1 - 0.011 15.3 0.2 0.02 14.4 0.1 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF1635 PF07795.6 CEP09267.1 - 0.96 8.7 4.1 0.6 9.4 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) PIH1 PF08190.7 CEP09268.1 - 5.2e-25 88.5 0.2 4.8e-23 82.1 0.0 2.1 1 1 1 2 2 2 2 pre-RNA processing PIH1/Nop17 TPR_11 PF13414.1 CEP09269.1 - 2.2e-10 40.0 0.2 3.7e-07 29.6 0.1 3.4 2 1 2 4 4 4 3 TPR repeat zf-MYND PF01753.13 CEP09269.1 - 1.7e-08 34.1 11.0 3.9e-08 33.0 7.6 1.7 1 1 0 1 1 1 1 MYND finger TPR_16 PF13432.1 CEP09269.1 - 1.3e-05 25.6 0.2 0.013 16.1 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP09269.1 - 7.5e-05 22.5 3.0 0.0067 16.3 0.5 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP09269.1 - 0.00015 21.2 10.5 0.00049 19.5 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP09269.1 - 0.00018 21.4 1.7 0.0043 17.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP09269.1 - 0.00018 21.1 10.5 0.033 14.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP09269.1 - 0.00048 19.7 12.7 0.2 11.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP09269.1 - 0.0011 19.2 0.3 23 5.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEP09269.1 - 0.015 15.8 0.0 0.28 11.9 0.0 3.1 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 CEP09269.1 - 0.039 13.8 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Lyase_aromatic PF00221.14 CEP09269.1 - 0.12 10.7 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Aromatic amino acid lyase ORC5_C PF14630.1 CEP09270.1 - 2.6e-75 253.3 0.2 1.4e-74 250.9 0.0 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 CEP09270.1 - 1.8e-08 34.5 0.0 4.4e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CEP09270.1 - 2.8e-08 33.9 0.0 6.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CEP09270.1 - 3e-05 23.8 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 CEP09270.1 - 0.00017 21.4 0.0 0.00059 19.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CEP09270.1 - 0.0004 20.3 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CEP09270.1 - 0.0027 17.8 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CEP09270.1 - 0.0038 16.3 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CEP09270.1 - 0.014 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CEP09270.1 - 0.084 12.4 0.3 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1439 PF07273.7 CEP09270.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) ubiquitin PF00240.18 CEP09271.1 - 6.6e-34 115.1 1.0 8.6e-34 114.7 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CEP09271.1 - 4.1e-29 99.9 11.7 6.6e-29 99.2 8.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CEP09271.1 - 9.2e-19 66.9 0.7 1.5e-18 66.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEP09271.1 - 1.8e-05 24.8 0.2 6.6e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CEP09271.1 - 0.00024 20.8 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 CEP09271.1 - 0.013 15.6 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEP09271.1 - 0.041 13.7 0.0 0.084 12.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fer2_3 PF13085.1 CEP09271.1 - 0.18 11.6 1.7 0.92 9.3 0.8 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ras PF00071.17 CEP09272.1 - 9.8e-48 161.6 0.0 2e-47 160.5 0.0 1.5 2 0 0 2 2 2 1 Ras family TYW3 PF02676.9 CEP09272.1 - 7.5e-44 149.3 0.0 1.1e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Miro PF08477.8 CEP09272.1 - 8.6e-15 55.2 0.0 2e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP09272.1 - 1.1e-09 37.7 0.0 1.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP09272.1 - 0.0019 17.4 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 CEP09272.1 - 0.01 15.9 0.4 0.08 13.1 0.1 2.5 2 1 0 2 2 2 0 RNA helicase G-alpha PF00503.15 CEP09272.1 - 0.013 14.2 0.3 0.028 13.1 0.0 1.7 2 1 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.7 CEP09272.1 - 0.049 12.9 0.6 0.13 11.4 0.1 1.8 1 1 1 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.4 CEP09272.1 - 0.1 12.0 0.0 6.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MRP-S26 PF14943.1 CEP09272.1 - 0.13 11.8 5.8 0.1 12.1 2.8 1.6 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 AAA_33 PF13671.1 CEP09272.1 - 0.36 10.6 0.1 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain Zn_Tnp_IS1595 PF12760.2 CEP09273.1 - 0.0085 15.8 4.9 0.43 10.4 0.2 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain NAD_binding_5 PF07994.7 CEP09273.1 - 0.14 11.6 3.8 0.22 10.9 2.6 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DivIC PF04977.10 CEP09273.1 - 0.15 11.5 11.2 0.39 10.2 7.8 1.8 1 0 0 1 1 1 0 Septum formation initiator LMBR1 PF04791.11 CEP09273.1 - 0.2 10.2 1.0 0.27 9.7 0.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 CEP09273.1 - 0.43 10.1 9.3 0.83 9.2 6.4 1.4 1 0 0 1 1 1 0 IncA protein RNase_H PF00075.19 CEP09274.1 - 0.09 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 RNase H La PF05383.12 CEP09275.1 - 4.5e-22 77.6 0.0 7.9e-22 76.8 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CEP09275.1 - 3.7e-08 33.2 0.1 8.7e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP09275.1 - 3e-07 29.9 0.4 7e-07 28.7 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP09275.1 - 4e-05 23.3 0.1 9.5e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTS_2-RNA PF01885.11 CEP09275.1 - 0.039 13.2 0.6 0.052 12.8 0.4 1.4 1 1 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Seryl_tRNA_N PF02403.17 CEP09275.1 - 0.94 9.5 13.1 0.031 14.3 1.8 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DSPc PF00782.15 CEP09275.1 - 6.9 6.2 6.3 1.3 8.6 0.1 2.5 2 1 1 3 3 3 0 Dual specificity phosphatase, catalytic domain Zn_clus PF00172.13 CEP09276.1 - 7e-05 22.6 13.8 0.00013 21.7 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4611 PF15387.1 CEP09276.1 - 0.0025 17.9 5.4 0.0099 16.0 0.6 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) Nefa_Nip30_N PF10187.4 CEP09277.1 - 1.4e-15 57.2 16.5 1.4e-15 57.2 11.4 2.1 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.8 CEP09277.1 - 0.17 11.0 21.2 0.23 10.6 14.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ALMT PF11744.3 CEP09277.1 - 1.1 7.8 4.7 1.4 7.5 3.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SNAPc_SNAP43 PF09808.4 CEP09277.1 - 2.7 7.6 7.8 0.3 10.7 2.4 1.6 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF3492 PF11997.3 CEP09277.1 - 6.6 6.1 8.4 2.1 7.8 4.0 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) RRM_5 PF13893.1 CEP09278.1 - 5.5e-15 54.9 0.3 3.2e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP09278.1 - 3e-14 52.7 0.2 4.2e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP09278.1 - 3.6e-09 36.1 1.0 0.0026 17.3 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP09278.1 - 3.1e-07 30.0 0.1 0.0082 15.8 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 CEP09278.1 - 0.00012 21.6 1.2 0.00027 20.5 0.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 CEP09278.1 - 0.00088 19.3 0.3 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 PWI domain RRM_3 PF08777.6 CEP09278.1 - 0.044 13.6 15.5 0.091 12.6 0.0 3.8 4 0 0 4 4 4 0 RNA binding motif DUF2762 PF10960.3 CEP09278.1 - 0.27 10.9 5.5 0.28 10.9 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) AAA_27 PF13514.1 CEP09278.1 - 0.37 8.4 19.2 0.51 7.9 13.3 1.1 1 0 0 1 1 1 0 AAA domain DUF3138 PF11336.3 CEP09278.1 - 7.9 4.5 8.4 6.9 4.7 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4613 PF15390.1 CEP09278.1 - 8.9 4.3 10.9 15 3.5 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1077 PF06417.7 CEP09279.1 - 1.7e-34 117.8 4.6 2e-34 117.6 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ERGIC_N PF13850.1 CEP09279.1 - 0.043 13.7 0.7 0.065 13.2 0.5 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MAPEG PF01124.13 CEP09280.1 - 0.053 13.1 13.2 0.27 10.8 9.1 1.9 1 1 0 1 1 1 0 MAPEG family DUF2975 PF11188.3 CEP09280.1 - 0.24 11.0 8.9 0.1 12.3 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF4181 PF13789.1 CEP09280.1 - 0.37 10.7 6.1 0.32 10.9 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF1218 PF06749.7 CEP09280.1 - 2.9 8.4 8.4 0.11 12.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2839 PF10999.3 CEP09280.1 - 7.3 6.7 6.6 4.6 7.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DEAD PF00270.24 CEP09281.1 - 4.2e-26 91.4 0.0 9e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP09281.1 - 3.9e-13 49.0 0.0 1.8e-12 46.9 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 CEP09281.1 - 0.012 16.1 0.2 0.053 14.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1998) DUF1344 PF07076.6 CEP09282.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Med19 PF10278.4 CEP09283.1 - 0.019 14.6 17.3 2.4 7.7 0.0 2.7 2 1 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Herpes_PAP PF03325.8 CEP09283.1 - 2.1 7.8 7.2 2.6 7.4 5.0 1.1 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein DUF3176 PF11374.3 CEP09284.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) SCO1-SenC PF02630.9 CEP09285.1 - 2.4e-51 173.8 0.0 3.5e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CEP09285.1 - 0.00032 20.7 0.2 0.00094 19.2 0.0 2.0 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 CEP09285.1 - 0.0022 17.6 0.1 0.0045 16.6 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family RhoGAP PF00620.22 CEP09286.1 - 1.6e-36 125.1 0.0 2.4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain PseudoU_synth_2 PF00849.17 CEP09287.1 - 7.7e-31 107.1 0.1 9.4e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase ACC_central PF08326.7 CEP09288.1 - 2.3e-223 743.3 2.3 2.8e-223 743.0 1.6 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CEP09288.1 - 9.6e-168 558.5 0.0 1.3e-167 558.0 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CEP09288.1 - 9.8e-55 185.0 0.0 2.1e-54 184.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CEP09288.1 - 6.1e-25 87.4 0.1 1.6e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CEP09288.1 - 2.8e-21 75.5 0.0 1.6e-20 73.1 0.0 2.3 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CEP09288.1 - 2.3e-14 52.7 0.0 4.9e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CEP09288.1 - 6.7e-13 48.7 0.0 2.2e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP09288.1 - 1.2e-10 40.6 0.0 0.003 16.3 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CEP09288.1 - 0.00035 19.9 0.0 0.00088 18.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CEP09288.1 - 0.00038 20.3 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CEP09288.1 - 0.0047 16.4 0.0 0.024 14.0 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CEP09288.1 - 0.011 15.1 0.0 0.03 13.6 0.0 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CEP09288.1 - 0.014 15.0 0.0 0.046 13.3 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like HTH_Tnp_Tc3_2 PF01498.13 CEP09290.1 - 8.7e-15 54.5 0.6 1.7e-14 53.5 0.4 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 CEP09290.1 - 0.057 14.2 0.1 0.12 13.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.1 CEP09290.1 - 0.064 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix DUF4339 PF14237.1 CEP09290.1 - 0.075 12.6 0.3 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) Ribosomal_60s PF00428.14 CEP09291.1 - 0.015 15.6 2.7 0.038 14.3 1.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Shadoo PF14999.1 CEP09291.1 - 0.019 14.8 3.7 0.022 14.5 1.1 1.9 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective zf-C2H2 PF00096.21 CEP09291.1 - 0.05 13.9 1.6 0.05 13.9 1.1 2.8 2 1 1 3 3 3 0 Zinc finger, C2H2 type DUF2110 PF09883.4 CEP09291.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) MULE PF10551.4 CEP09293.1 - 0.033 14.3 0.1 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 MULE transposase domain GATA PF00320.22 CEP09295.1 - 5.5e-29 99.2 19.7 1.9e-14 52.6 5.2 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CEP09295.1 - 0.0091 15.3 6.7 0.081 12.2 0.3 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 CEP09295.1 - 0.047 13.3 0.3 0.047 13.3 0.2 2.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.2 CEP09295.1 - 0.13 12.0 8.0 0.78 9.6 0.4 2.8 2 0 0 2 2 2 0 Double zinc ribbon DUF2638 PF10937.3 CEP09295.1 - 1.6 9.8 6.5 0.59 11.1 1.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2638) Cytochrome_C7 PF14522.1 CEP09295.1 - 2.3 7.9 12.9 0.056 13.0 0.8 3.0 2 1 0 2 2 2 0 Cytochrome c7 eIF-5_eIF-2B PF01873.12 CEP09295.1 - 2.9 7.5 6.6 5.2 6.7 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Phlebovirus_NSM PF07246.6 CEP09296.1 - 0.71 8.9 3.1 1.3 8.1 2.1 1.3 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M MSG PF02349.10 CEP09296.1 - 3.2 7.7 7.2 0.4 10.6 1.7 1.8 2 0 0 2 2 2 0 Major surface glycoprotein zf-C3HC4_3 PF13920.1 CEP09297.1 - 2.1e-09 36.9 5.0 3.5e-09 36.1 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP09297.1 - 3.6e-09 36.4 9.9 6.6e-09 35.6 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 CEP09297.1 - 1.5e-07 30.8 1.4 3e-07 29.9 1.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 CEP09297.1 - 5.3e-07 29.3 7.7 9e-07 28.6 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEP09297.1 - 1.7e-06 27.6 9.1 2.9e-06 26.9 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEP09297.1 - 3.1e-06 26.7 10.0 6.5e-06 25.6 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 CEP09297.1 - 2.4e-05 23.3 2.3 6.2e-05 22.0 1.6 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C3HC4_4 PF15227.1 CEP09297.1 - 6.8e-05 22.6 8.1 0.00017 21.3 5.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP09297.1 - 0.00013 21.6 5.2 0.00013 21.6 3.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 CEP09297.1 - 0.0043 16.5 2.3 0.0084 15.6 1.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 CEP09297.1 - 0.18 11.3 1.8 0.36 10.3 1.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.1 CEP09297.1 - 0.31 10.6 4.9 0.69 9.4 3.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 CEP09297.1 - 0.86 9.7 6.6 3.3 7.8 4.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger Abhydrolase_1 PF00561.15 CEP09299.1 - 2.8e-25 89.2 0.0 4.2e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEP09299.1 - 4.1e-13 49.7 0.0 2.4e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CEP09299.1 - 0.0008 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CEP09299.1 - 0.00099 18.8 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family GAS2 PF02187.12 CEP09300.1 - 4.7e-08 32.6 0.1 1.3e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.3 CEP09300.1 - 0.0041 16.7 0.8 0.028 14.0 0.2 2.7 3 0 0 3 3 3 1 CAMSAP CH domain CH PF00307.26 CEP09300.1 - 0.0062 16.5 2.3 0.13 12.3 0.1 4.0 3 0 0 3 3 3 1 Calponin homology (CH) domain VBS PF08913.5 CEP09300.1 - 0.05 13.8 3.5 1.2 9.4 0.7 3.8 3 0 0 3 3 3 0 Vinculin Binding Site DUF4250 PF14056.1 CEP09300.1 - 3.9 7.2 9.6 6.3 6.6 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) ArsB PF02040.10 CEP09302.1 - 6.9e-26 91.1 33.0 4e-14 52.3 11.9 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.11 CEP09302.1 - 1.6e-13 50.0 14.8 1.6e-13 50.0 10.3 3.1 2 1 1 3 3 3 2 Citrate transporter Ndc1_Nup PF09531.5 CEP09302.1 - 0.87 7.9 12.5 2.5 6.4 8.6 1.7 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2457 PF10446.4 CEP09303.1 - 0.017 13.8 5.2 0.022 13.5 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4268 PF14088.1 CEP09303.1 - 0.018 14.7 0.4 0.025 14.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Homeobox_KN PF05920.6 CEP09303.1 - 0.18 11.5 0.3 0.4 10.4 0.2 1.7 1 1 0 1 1 1 0 Homeobox KN domain Glyco_transf_49 PF13896.1 CEP09305.1 - 5.7e-16 58.4 0.1 5.6e-10 38.8 0.0 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan RGP PF03214.8 CEP09305.1 - 0.047 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide NST1 PF13945.1 CEP09305.1 - 1.3 9.0 9.4 10 6.1 0.1 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator RNA_pol_3_Rpc31 PF11705.3 CEP09307.1 - 0.17 11.7 10.2 0.22 11.4 7.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CAF1A PF12253.3 CEP09307.1 - 0.26 11.4 8.4 0.27 11.3 5.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A ANAPC15 PF15243.1 CEP09307.1 - 0.28 11.2 10.6 0.37 10.8 7.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF2457 PF10446.4 CEP09307.1 - 0.33 9.6 11.6 0.33 9.6 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.8 CEP09307.1 - 1 9.1 10.1 1 9.2 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 CEP09307.1 - 1.6 7.9 8.1 1.6 7.9 5.6 1.0 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 CEP09307.1 - 2.6 7.5 10.7 2.7 7.5 7.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 CEP09307.1 - 3.8 7.1 11.9 4.3 6.9 8.3 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1762 PF08574.5 CEP09307.1 - 5.1 7.5 14.9 0.78 10.1 6.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1762) CDC45 PF02724.9 CEP09307.1 - 5.1 4.9 8.6 5 5.0 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Velvet PF11754.3 CEP09308.1 - 4.5e-49 166.8 0.0 9.5e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 Velvet factor tRNA-synt_2b PF00587.20 CEP09308.1 - 1.5e-44 151.6 0.8 2.6e-44 150.8 0.6 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEP09308.1 - 1.8e-17 63.0 0.2 3.6e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 CEP09308.1 - 4.6e-14 52.0 0.0 1.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 CEP09308.1 - 6.4e-13 48.3 0.0 2.2e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 TGS domain Velvet PF11754.3 CEP09309.1 - 2.6e-54 183.9 0.1 5.2e-54 182.9 0.0 1.5 1 1 1 2 2 2 1 Velvet factor START PF01852.14 CEP09310.1 - 1e-09 38.0 0.0 1.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 START domain RabGAP-TBC PF00566.13 CEP09311.1 - 4.4e-53 179.9 0.1 4.4e-53 179.9 0.1 3.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain IncA PF04156.9 CEP09311.1 - 0.0065 16.0 8.5 0.0065 16.0 5.9 4.5 3 1 0 4 4 4 2 IncA protein TSC22 PF01166.13 CEP09311.1 - 0.29 11.1 14.7 0.14 12.1 2.4 4.2 2 1 1 3 3 3 0 TSC-22/dip/bun family Sel1 PF08238.7 CEP09313.1 - 1.5e-39 133.5 22.2 1.7e-08 34.8 0.0 8.1 8 0 0 8 8 8 7 Sel1 repeat Nro1 PF12753.2 CEP09313.1 - 0.055 12.4 0.2 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 TPR_6 PF13174.1 CEP09313.1 - 0.058 13.8 0.2 0.058 13.8 0.1 4.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP09313.1 - 0.12 11.9 7.7 0.4 10.3 1.6 3.9 3 1 1 4 4 4 0 TPR repeat TPR_1 PF00515.23 CEP09313.1 - 0.4 10.3 0.1 0.4 10.3 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP09313.1 - 0.57 10.1 7.9 0.44 10.5 0.6 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP09313.1 - 1.3 8.9 5.0 1.3 9.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP09313.1 - 1.7 8.6 4.4 11 6.0 0.4 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 CEP09313.1 - 2.7 7.9 16.2 5.4 6.9 0.0 5.2 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF605 PF04652.11 CEP09313.1 - 3 7.1 12.6 4.4 6.6 8.8 1.2 1 0 0 1 1 1 0 Vta1 like Pyr_redox_2 PF07992.9 CEP09314.1 - 5.2e-29 101.5 0.1 6.2e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP09314.1 - 1.6e-15 57.2 0.4 3.4e-13 49.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP09314.1 - 1.5e-09 38.2 0.1 6e-05 23.1 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CEP09314.1 - 1.3e-05 24.2 5.7 0.015 14.1 0.2 4.2 3 2 2 5 5 5 2 Glucose inhibited division protein A DAO PF01266.19 CEP09314.1 - 1.6e-05 24.0 1.5 0.087 11.7 0.0 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP09314.1 - 4.7e-05 22.4 2.3 0.0034 16.2 0.1 2.9 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 CEP09314.1 - 0.00016 20.8 0.0 0.00087 18.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 CEP09314.1 - 0.0005 20.0 0.3 0.0061 16.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CEP09314.1 - 0.0012 18.0 0.4 0.026 13.6 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CEP09314.1 - 0.0023 18.1 0.0 0.25 11.5 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 CEP09314.1 - 0.0039 15.7 0.2 0.048 12.1 0.1 2.7 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.14 CEP09314.1 - 0.0045 16.0 0.1 0.15 11.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 CEP09314.1 - 0.0047 17.0 0.0 0.77 9.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 CEP09314.1 - 0.017 14.0 0.1 0.39 9.5 0.1 2.6 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CEP09314.1 - 0.019 14.7 0.3 5.9 6.6 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 CEP09314.1 - 0.033 12.8 0.1 0.82 8.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 CEP09314.1 - 0.046 13.4 0.1 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.14 CEP09314.1 - 0.084 11.0 0.0 0.21 9.7 0.0 1.6 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Na_H_Exchanger PF00999.16 CEP09315.1 - 8.1e-66 222.0 40.7 1.2e-65 221.5 28.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FAD_binding_2 PF00890.19 CEP09316.1 - 9.6e-83 278.3 2.5 1.1e-82 278.1 1.7 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEP09316.1 - 5.7e-12 45.2 2.5 6.7e-06 25.2 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEP09316.1 - 8.4e-09 35.5 6.6 4.5e-08 33.2 1.9 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP09316.1 - 1.2e-08 34.4 3.5 8e-08 31.7 2.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP09316.1 - 1.6e-08 34.4 0.5 3.4e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CEP09316.1 - 4.1e-08 32.1 4.3 8.1e-06 24.5 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 CEP09316.1 - 2.8e-07 29.7 8.6 0.00022 20.2 0.2 3.2 3 0 0 3 3 3 3 Glucose inhibited division protein A Thi4 PF01946.12 CEP09316.1 - 6.1e-07 28.7 2.7 0.00074 18.6 0.0 3.2 3 0 0 3 3 3 2 Thi4 family Pyr_redox_3 PF13738.1 CEP09316.1 - 4.2e-06 26.9 0.9 1.9e-05 24.8 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP09316.1 - 0.0011 17.9 1.2 0.0065 15.4 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CEP09316.1 - 0.0097 14.9 0.4 0.017 14.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.14 CEP09316.1 - 0.011 14.9 0.3 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.22 CEP09316.1 - 0.026 14.9 2.9 0.035 14.5 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP09316.1 - 0.033 13.9 1.7 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 CEP09316.1 - 0.12 10.9 0.6 0.2 10.2 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase KOW PF00467.24 CEP09316.1 - 0.4 10.4 5.7 3.5 7.4 0.0 3.7 4 0 0 4 4 4 0 KOW motif Amino_oxidase PF01593.19 CEP09317.1 - 1e-45 156.6 0.0 1.1e-33 117.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEP09317.1 - 1.5e-09 37.7 0.0 4.1e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CEP09317.1 - 0.00098 19.2 0.1 0.012 15.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Spore_IV_A PF09547.5 CEP09320.1 - 0.027 13.1 0.6 0.034 12.8 0.4 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) DUF4182 PF13790.1 CEP09320.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4182) Menin PF05053.8 CEP09322.1 - 2.9 5.9 8.3 3.4 5.7 5.7 1.1 1 0 0 1 1 1 0 Menin Big_3_3 PF13750.1 CEP09324.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) PT PF04886.7 CEP09325.1 - 1.6 8.1 7.0 2.6 7.4 0.8 2.9 2 0 0 2 2 2 0 PT repeat DUF1836 PF08876.6 CEP09326.1 - 0.084 12.6 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) rve PF00665.21 CEP09327.1 - 0.0066 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP09328.1 - 4.3e-15 55.6 0.0 4.8e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl_CoA_thio PF02551.10 CEP09328.1 - 0.045 13.3 0.1 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Acyl-CoA thioesterase PE PF00934.15 CEP09328.1 - 0.057 13.5 0.3 0.081 13.0 0.2 1.1 1 0 0 1 1 1 0 PE family ImpE PF07024.8 CEP09328.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 ImpE protein Chromo PF00385.19 CEP09329.1 - 0.00049 19.7 0.3 0.00085 18.9 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acyl-thio_N PF12590.3 CEP09332.1 - 6.9 7.1 6.7 5.7 7.4 2.1 2.1 1 1 1 2 2 2 0 Acyl-ATP thioesterase DUF2034 PF10356.4 CEP09333.1 - 8.3e-22 77.2 5.8 6.6e-11 41.7 0.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CEP09333.1 - 6e-08 32.4 0.0 1e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease PNP_UDP_1 PF01048.15 CEP09334.1 - 4.2e-24 84.8 0.0 5.4e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Epimerase PF01370.16 CEP09335.1 - 3.8e-70 235.9 0.0 4.9e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CEP09335.1 - 1.5e-09 37.2 0.0 2.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 CEP09335.1 - 5.7e-05 22.4 0.0 9.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 CEP09335.1 - 9.7e-05 21.4 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CEP09335.1 - 0.0051 16.8 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase_Csub PF13950.1 CEP09335.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit adh_short PF00106.20 CEP09335.1 - 0.039 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TFIIB PF00382.14 CEP09336.1 - 1e-45 153.3 2.1 8.4e-25 86.3 0.6 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CEP09336.1 - 1.2e-14 53.3 1.0 2e-14 52.6 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 CEP09336.1 - 0.00018 21.4 0.3 0.07 13.0 0.0 2.4 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 CEP09336.1 - 0.022 14.3 0.9 0.4 10.2 0.3 2.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain HTH_23 PF13384.1 CEP09336.1 - 0.038 13.6 0.2 0.58 9.8 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain RB_B PF01857.15 CEP09336.1 - 0.085 12.3 0.4 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain A2L_zn_ribbon PF08792.5 CEP09336.1 - 0.46 10.0 2.1 3.8 7.1 0.1 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain PH PF00169.24 CEP09337.1 - 1.4e-12 47.6 0.2 8.3e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 CEP09337.1 - 0.0002 21.5 1.4 0.0034 17.6 1.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain HH_signal PF01085.13 CEP09338.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Hedgehog amino-terminal signalling domain Lipase_GDSL_2 PF13472.1 CEP09339.1 - 3.7e-05 23.9 0.0 6.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CEP09339.1 - 0.021 14.6 0.3 0.095 12.5 0.2 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase ATP-synt_S1 PF05827.7 CEP09340.1 - 5e-20 71.9 11.0 1.7e-16 60.4 1.3 2.0 1 1 1 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF1049 PF06305.6 CEP09340.1 - 0.11 11.9 1.1 0.22 11.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4014 PF13198.1 CEP09341.1 - 0.083 13.3 0.1 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Cyclin PF08613.6 CEP09341.1 - 0.75 10.1 0.0 0.75 10.1 0.0 3.1 2 1 1 3 3 3 0 Cyclin GIDA PF01134.17 CEP09342.1 - 2.5e-153 510.6 0.0 3.1e-153 510.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CEP09342.1 - 2.2e-14 53.2 0.1 7.6e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 CEP09342.1 - 1.9e-07 31.1 0.6 1.1e-06 28.7 0.6 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP09342.1 - 1.5e-06 27.5 0.1 2.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP09342.1 - 9.1e-05 21.4 2.4 9.7e-05 21.3 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CEP09342.1 - 0.0002 20.3 0.5 0.27 10.1 0.2 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 CEP09342.1 - 0.00074 18.0 3.3 0.0062 15.0 0.3 2.5 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.16 CEP09342.1 - 0.0084 15.6 0.1 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 CEP09342.1 - 0.019 14.7 0.1 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CEP09342.1 - 0.12 12.3 0.2 0.51 10.3 0.1 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 CEP09343.1 - 8.2e-39 132.5 0.1 5.3e-38 129.9 0.0 2.1 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 CEP09343.1 - 2e-26 91.5 0.0 4e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 CEP09343.1 - 5.2e-23 80.4 0.6 1.2e-22 79.2 0.4 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CEP09343.1 - 9.2e-17 60.1 2.7 2.7e-16 58.6 1.9 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CEP09343.1 - 0.00023 21.2 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 CEP09343.1 - 0.0026 17.3 0.8 0.0093 15.5 0.0 2.2 2 0 0 2 2 2 1 MoeZ/MoeB domain UAE_UbL PF14732.1 CEP09343.1 - 0.0072 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ecm33 PF12454.3 CEP09343.1 - 0.021 14.7 0.8 0.055 13.3 0.6 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_7 PF13241.1 CEP09343.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding UTP15_C PF09384.5 CEP09344.1 - 9e-05 22.1 0.1 0.0082 15.8 0.1 2.4 2 0 0 2 2 2 2 UTP15 C terminal CelD_N PF02927.9 CEP09344.1 - 0.037 14.2 0.1 2.1 8.6 0.0 2.8 2 0 0 2 2 2 0 N-terminal ig-like domain of cellulase Fasciclin PF02469.17 CEP09345.1 - 1.5e-29 102.5 7.6 1.8e-18 66.8 1.4 2.7 2 1 0 2 2 2 2 Fasciclin domain Adeno_E1B_55K PF01696.12 CEP09345.1 - 0.089 11.2 0.1 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Asn_synthase PF00733.16 CEP09346.1 - 3.9e-57 193.6 0.0 5.5e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CEP09346.1 - 5.5e-38 129.5 0.0 1.1e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CEP09346.1 - 2.9e-30 104.9 0.0 4.9e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CEP09346.1 - 0.00013 20.7 0.0 0.13 10.9 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 CEP09346.1 - 0.0016 17.6 0.0 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 CEP09346.1 - 0.064 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase F-box-like PF12937.2 CEP09347.1 - 6.3e-09 35.4 0.4 1.4e-08 34.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP09347.1 - 9.8e-08 31.4 0.8 2.9e-07 29.9 0.6 1.9 1 0 0 1 1 1 1 F-box domain MYCBPAP PF14646.1 CEP09347.1 - 0.062 12.0 0.0 0.27 9.9 0.0 1.9 1 1 1 2 2 2 0 MYCBP-associated protein family Ssl1 PF04056.9 CEP09348.1 - 3.2e-83 278.0 0.0 4.1e-83 277.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 CEP09348.1 - 1.2e-14 54.0 13.6 1.2e-14 54.0 9.4 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 CEP09348.1 - 5.5e-10 39.6 0.0 8.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 CEP09348.1 - 0.00048 19.4 0.8 0.00083 18.6 0.6 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 IBR PF01485.16 CEP09348.1 - 0.15 11.9 16.7 0.023 14.5 5.7 2.6 2 0 0 2 2 2 0 IBR domain DZR PF12773.2 CEP09348.1 - 7.6 6.4 21.9 3.2 7.6 2.3 3.3 2 1 1 3 3 3 0 Double zinc ribbon RNA_lig_T4_1 PF09511.5 CEP09349.1 - 1.9e-67 226.9 0.8 2.9e-67 226.3 0.5 1.3 1 0 0 1 1 1 1 RNA ligase DENN PF02141.16 CEP09349.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 DENN (AEX-3) domain Abhydrolase_5 PF12695.2 CEP09350.1 - 2.3e-08 33.9 0.0 2.9e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP09350.1 - 2.6e-07 30.7 0.1 6.8e-07 29.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP09350.1 - 0.021 14.0 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CEP09350.1 - 0.14 11.5 0.0 0.6 9.5 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DDE_3 PF13358.1 CEP09351.1 - 3e-16 59.4 0.0 5.5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP09351.1 - 0.0014 18.6 0.2 0.27 11.3 0.0 2.6 1 1 1 2 2 2 2 Transposase HTH_11 PF08279.7 CEP09351.1 - 0.019 14.6 0.0 0.063 12.9 0.0 1.9 1 0 0 1 1 1 0 HTH domain DUF524 PF04411.7 CEP09352.1 - 0.082 12.7 4.0 0.2 11.5 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF524) DDE_3 PF13358.1 CEP09353.1 - 3e-20 72.4 0.1 6.9e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP09353.1 - 0.0042 17.1 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_29 PF13551.1 CEP09353.1 - 0.014 15.5 2.0 0.041 14.0 0.0 2.8 3 1 1 4 4 4 0 Winged helix-turn helix HTH_23 PF13384.1 CEP09353.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain SRP54 PF00448.17 CEP09354.1 - 3.6e-49 166.8 0.1 7.3e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CEP09354.1 - 1.9e-45 155.4 18.6 3.4e-45 154.6 12.9 1.4 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 CEP09354.1 - 3.3e-07 30.3 0.1 4.2e-06 26.7 0.0 3.0 3 1 0 3 3 3 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 CEP09354.1 - 4.4e-07 29.5 0.9 8.9e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CEP09354.1 - 0.00017 20.4 0.0 0.00046 19.0 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 CEP09354.1 - 0.0012 18.8 0.0 0.059 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 CEP09354.1 - 0.0065 15.9 0.3 0.05 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 CEP09354.1 - 0.0082 16.2 0.0 0.028 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CEP09354.1 - 0.013 15.1 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CEP09354.1 - 0.044 13.7 0.2 0.21 11.5 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase DRY_EERY PF09750.4 CEP09356.1 - 6.1e-08 32.7 0.1 6.1e-08 32.7 0.1 3.6 3 1 0 3 3 3 1 Alternative splicing regulator RHH_1 PF01402.16 CEP09356.1 - 2.2e-05 24.1 0.3 0.07 13.0 0.0 3.0 2 0 0 2 2 2 2 Ribbon-helix-helix protein, copG family Seipin PF06775.9 CEP09357.1 - 2.1e-39 135.0 4.8 1.6e-38 132.2 3.3 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Haemocyan_bet_s PF14830.1 CEP09357.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Haemocyanin beta-sandwich NDUFA12 PF05071.11 CEP09358.1 - 0.0033 17.8 4.1 0.0052 17.2 2.6 1.7 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 RNase_H2-Ydr279 PF09468.5 CEP09358.1 - 0.054 12.6 0.8 0.062 12.4 0.5 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3398 PF11878.3 CEP09358.1 - 0.062 13.1 0.4 0.078 12.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) DUF4392 PF14336.1 CEP09358.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) EZH2_WD-Binding PF11616.3 CEP09358.1 - 0.11 12.4 0.9 0.27 11.1 0.6 1.7 1 0 0 1 1 1 0 WD repeat binding protein EZH2 Muted PF14942.1 CEP09358.1 - 0.2 11.5 3.7 0.23 11.3 2.5 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DDE_Tnp_1_7 PF13843.1 CEP09365.1 - 3.3e-46 157.9 0.0 3.9e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.16 CEP09365.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain zf-C3HC4_2 PF13923.1 CEP09365.1 - 0.15 12.1 7.8 0.33 11.0 5.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HTH_Tnp_Tc3_2 PF01498.13 CEP09366.1 - 1.9e-12 47.0 1.5 1.9e-12 47.0 1.0 1.8 2 0 0 2 2 1 1 Transposase zf-CCHC PF00098.18 CEP09366.1 - 0.0082 16.0 0.3 0.0082 16.0 0.2 4.0 4 0 0 4 4 4 2 Zinc knuckle HTH_32 PF13565.1 CEP09366.1 - 0.0095 16.7 0.8 0.24 12.2 0.2 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP09366.1 - 0.038 14.1 1.6 0.074 13.2 0.2 2.0 2 0 0 2 2 2 0 Winged helix-turn helix zinc_ribbon_5 PF13719.1 CEP09366.1 - 0.039 13.5 0.7 3.6 7.2 0.0 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C4_Topoisom PF01396.14 CEP09366.1 - 0.093 12.2 2.5 4.3 6.9 0.1 2.9 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_4 PF13717.1 CEP09366.1 - 0.16 11.6 3.2 2.8 7.6 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.1 CEP09366.1 - 1.2 8.8 10.4 0.3 10.8 0.2 3.7 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DUF164 PF02591.10 CEP09366.1 - 2 8.3 5.8 7.1 6.5 2.1 2.9 2 1 0 2 2 2 0 Putative zinc ribbon domain zf-ribbon_3 PF13248.1 CEP09366.1 - 2.3 7.5 7.8 1 8.6 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 CEP09366.1 - 3 7.7 10.5 2.6 7.9 1.7 3.1 2 2 0 2 2 2 0 Double zinc ribbon Ogr_Delta PF04606.7 CEP09366.1 - 3.1 7.5 6.9 3 7.5 0.3 3.2 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 CEP09366.1 - 4.4 7.3 7.7 2 8.4 0.4 3.1 4 0 0 4 4 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 CEP09366.1 - 8.8 5.9 8.3 1.4 8.5 0.1 3.1 4 0 0 4 4 4 0 zinc-ribbon domain DUF1143 PF06608.6 CEP09369.1 - 0.11 12.4 0.3 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) zf-C2HC_2 PF13913.1 CEP09371.1 - 0.067 12.8 0.3 0.067 12.8 0.2 2.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.2 CEP09371.1 - 0.15 11.9 6.4 1 9.1 0.4 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Striatin PF08232.7 CEP09371.1 - 0.54 10.5 24.4 0.061 13.6 6.9 2.9 2 0 0 2 2 2 0 Striatin family IncA PF04156.9 CEP09371.1 - 3.6 7.1 10.3 1 8.9 1.9 2.4 2 0 0 2 2 2 0 IncA protein DUF572 PF04502.8 CEP09371.1 - 6 5.9 29.0 0.83 8.8 7.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Phage_integrase PF00589.17 CEP09372.1 - 0.00038 20.1 0.0 0.00064 19.4 0.0 1.3 1 1 0 1 1 1 1 Phage integrase family FlxA PF14282.1 CEP09373.1 - 0.16 11.9 3.7 0.08 12.9 1.2 1.5 2 0 0 2 2 2 0 FlxA-like protein DUF3138 PF11336.3 CEP09373.1 - 0.23 9.5 0.7 0.28 9.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DNA_pol_A_exo1 PF01612.15 CEP09376.1 - 1.9e-07 30.7 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Eapp_C PF10238.4 CEP09377.1 - 0.11 12.3 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Helitron_like_N PF14214.1 CEP09378.1 - 4.8e-13 49.2 0.0 1.2e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_1 PF00078.22 CEP09380.1 - 9.9e-33 113.2 0.0 1.9e-32 112.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RepB PF07506.6 CEP09385.1 - 0.12 12.2 0.2 0.22 11.3 0.1 1.5 1 1 0 1 1 1 0 RepB plasmid partitioning protein HAD PF12710.2 CEP09388.1 - 2.9e-12 47.1 0.1 4.1e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP09388.1 - 4.1e-07 30.3 0.1 2.8e-05 24.3 0.0 2.6 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP09388.1 - 0.0024 18.2 0.0 0.031 14.6 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CEP09388.1 - 0.082 12.2 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) SpoU_methylas_C PF12105.3 CEP09388.1 - 0.11 12.1 0.0 7.7 6.1 0.0 2.3 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal Kelch_5 PF13854.1 CEP09389.1 - 9.7e-17 60.5 4.0 3.8e-06 26.7 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CEP09389.1 - 3e-15 55.8 13.4 2.5e-06 27.4 0.0 5.4 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP09389.1 - 9.1e-15 54.1 10.2 3.6e-06 26.6 0.1 5.3 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP09389.1 - 2.8e-12 46.2 12.2 0.031 14.4 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CEP09389.1 - 0.0001 21.7 14.7 0.4 10.2 0.4 5.7 6 3 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CEP09389.1 - 0.0082 15.8 9.4 1.8 8.4 0.2 5.3 5 2 0 5 5 5 1 Kelch motif PIRT PF15099.1 CEP09389.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family CotJB PF12652.2 CEP09390.1 - 0.13 12.3 0.0 0.51 10.4 0.0 2.0 1 0 0 1 1 1 0 CotJB protein Abhydrolase_1 PF00561.15 CEP09391.1 - 5e-41 140.7 0.0 1.3e-40 139.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEP09391.1 - 5.1e-12 46.1 0.0 1e-11 45.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP09391.1 - 0.0076 16.0 0.0 0.058 13.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family 2-Hacid_dh_C PF02826.14 CEP09392.1 - 3.3e-47 159.9 0.0 5.7e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEP09392.1 - 3.2e-33 114.0 0.1 4.2e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CEP09392.1 - 1.9e-07 31.0 1.1 5.1e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Voldacs PF03517.8 CEP09392.1 - 0.027 14.3 0.1 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling 3HCDH_N PF02737.13 CEP09392.1 - 0.12 12.0 0.6 0.76 9.3 0.2 2.3 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IER PF05760.7 CEP09393.1 - 0.0011 19.0 19.1 0.0019 18.2 13.2 1.4 1 0 0 1 1 1 1 Immediate early response protein (IER) ABC2_membrane_2 PF12679.2 CEP09393.1 - 0.0014 17.5 0.1 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Yip1 PF04893.12 CEP09393.1 - 0.013 14.9 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Yip1 domain OPT PF03169.10 CEP09393.1 - 0.02 13.3 0.7 0.13 10.6 0.0 2.0 2 0 0 2 2 2 0 OPT oligopeptide transporter protein Borrelia_P83 PF05262.6 CEP09393.1 - 0.11 10.7 9.5 0.14 10.4 6.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1282 PF06930.7 CEP09393.1 - 0.12 12.0 0.1 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Na_trans_assoc PF06512.8 CEP09393.1 - 0.12 12.3 14.3 0.07 13.0 8.0 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated Tetraspannin PF00335.15 CEP09393.1 - 0.14 11.3 0.1 0.76 9.0 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family Mitofilin PF09731.4 CEP09393.1 - 0.18 10.4 14.7 0.23 10.0 10.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ctr PF04145.10 CEP09393.1 - 0.43 10.6 12.8 5.5 7.0 0.0 3.2 2 1 0 2 2 2 0 Ctr copper transporter family COX14 PF14880.1 CEP09393.1 - 0.52 9.9 0.0 0.52 9.9 0.0 2.8 3 0 0 3 3 2 0 Cytochrome oxidase c assembly EphA2_TM PF14575.1 CEP09393.1 - 0.78 10.1 11.3 2.3 8.6 0.0 3.4 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain Utp14 PF04615.8 CEP09393.1 - 1.9 6.5 16.2 2.7 6.0 11.2 1.3 1 0 0 1 1 1 0 Utp14 protein FAM176 PF14851.1 CEP09393.1 - 2.9 7.5 10.1 1.5 8.5 2.0 2.9 2 1 1 3 3 3 0 FAM176 family OATP PF03137.15 CEP09393.1 - 6.6 4.6 5.7 13 3.6 3.9 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Plasmodium_Vir PF05795.6 CEP09393.1 - 9.2 5.3 17.2 6.4e+02 -0.8 11.9 2.2 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Exo_endo_phos PF03372.18 CEP09394.1 - 7e-19 68.7 0.0 8.5e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP09394.1 - 2.4e-08 33.6 0.0 4.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Sugar_tr PF00083.19 CEP09395.1 - 8e-115 383.9 21.9 9.1e-115 383.7 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP09395.1 - 2.5e-19 69.2 57.1 5.7e-17 61.4 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AIP3 PF03915.8 CEP09396.1 - 0.06 12.2 0.6 0.069 12.0 0.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Glycos_transf_2 PF00535.21 CEP09398.1 - 0.00041 20.0 0.0 0.00081 19.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 PMP22_Claudin PF00822.15 CEP09398.1 - 0.048 13.3 0.4 0.1 12.2 0.1 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Pik1 PF11522.3 CEP09398.1 - 0.061 13.0 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 CRAL_TRIO PF00650.15 CEP09399.1 - 1.8e-27 95.7 0.3 7.7e-27 93.7 0.2 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP09399.1 - 0.0015 18.6 0.1 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEP09399.1 - 0.061 13.2 0.2 0.15 11.9 0.2 1.7 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3020 PF11223.3 CEP09400.1 - 3.2e-09 37.0 1.9 3.2e-09 37.0 1.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3020) DUF3464 PF11947.3 CEP09400.1 - 7.3 6.0 7.8 1.4 8.3 2.6 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3464) Vezatin PF12632.2 CEP09401.1 - 1.2e-26 93.2 9.0 1.2e-26 93.2 6.2 1.8 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes OmdA PF13376.1 CEP09401.1 - 3.1 7.5 6.8 6 6.6 0.1 2.8 2 1 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated IncA PF04156.9 CEP09401.1 - 3.8 7.0 17.7 9.2 5.8 9.6 2.7 2 1 0 2 2 2 0 IncA protein Methyltrn_RNA_3 PF02598.12 CEP09402.1 - 5.8e-80 268.7 0.0 6.8e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Grp1_Fun34_YaaH PF01184.14 CEP09404.1 - 1.1e-70 237.1 16.5 1.3e-70 236.9 11.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.2 CEP09404.1 - 7.6 6.5 9.3 2.4 8.1 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) TPR_11 PF13414.1 CEP09405.1 - 2.6e-14 52.6 7.3 0.00033 20.2 0.2 5.3 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.1 CEP09405.1 - 2.2e-10 40.9 5.8 0.008 16.8 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP09405.1 - 3.6e-09 36.1 0.8 1.2 9.4 0.0 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TOM20_plant PF06552.7 CEP09405.1 - 1.3e-06 28.1 5.8 5.4e-05 22.8 0.5 3.0 3 0 0 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_14 PF13428.1 CEP09405.1 - 5.7e-06 26.5 3.2 0.32 11.7 0.0 5.3 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP09405.1 - 1.7e-05 25.0 7.5 0.0089 16.3 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEP09405.1 - 2.4e-05 23.7 8.9 0.42 10.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Ribonuc_L-PSP PF01042.16 CEP09405.1 - 0.0005 19.8 0.1 0.11 12.2 0.1 2.7 2 0 0 2 2 2 1 Endoribonuclease L-PSP TPR_2 PF07719.12 CEP09405.1 - 0.0037 17.0 12.7 1.2 9.2 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP09405.1 - 0.013 15.4 7.5 0.77 9.7 1.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP09405.1 - 0.22 11.3 13.4 3.2 7.7 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CEP09405.1 - 0.67 10.1 8.7 0.59 10.3 0.1 4.3 2 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CEP09405.1 - 1 9.3 6.2 1.8 8.5 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 CEP09405.1 - 3.9 8.2 6.3 18 6.1 0.7 3.5 3 0 0 3 3 3 0 Sel1 repeat Kelch_4 PF13418.1 CEP09407.1 - 9.8e-11 41.2 13.5 0.017 14.8 0.5 6.0 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP09407.1 - 3.8e-10 39.6 6.9 0.00075 19.5 0.7 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP09407.1 - 2.5e-08 33.6 5.6 0.15 12.0 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CEP09407.1 - 3.4e-07 30.1 15.4 0.11 12.6 0.1 5.6 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CEP09407.1 - 4.3e-07 29.4 2.3 0.23 11.2 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CEP09407.1 - 5.7e-06 25.7 9.7 0.0015 17.9 0.0 5.0 5 1 0 5 5 5 2 Kelch motif SKG6 PF08693.5 CEP09407.1 - 0.0089 15.3 2.4 0.021 14.1 1.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 CEP09407.1 - 0.022 13.4 1.0 0.044 12.4 0.7 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Peptidase_M36 PF02128.10 CEP09408.1 - 8.6e-137 455.9 8.7 1.5e-136 455.1 6.0 1.4 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 CEP09408.1 - 1.3e-11 43.7 1.2 4.4e-11 42.0 0.8 2.0 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Glyco_transf_92 PF01697.22 CEP09408.1 - 0.0027 17.0 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 FYRC PF05965.9 CEP09409.1 - 3.1e-18 65.3 0.0 1.1e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.9 CEP09409.1 - 2.1e-17 62.3 0.0 3.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus O-FucT PF10250.4 CEP09410.1 - 5.5e-18 65.2 2.0 1.1e-11 44.4 0.8 2.8 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase RLAN PF14401.1 CEP09410.1 - 0.0018 17.8 0.0 0.0041 16.6 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain LON PF02190.11 CEP09411.1 - 6.7e-23 81.4 0.0 2.2e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 CEP09411.1 - 2.5e-10 40.1 14.6 4.8e-10 39.2 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP09411.1 - 3e-10 39.7 15.2 6.3e-10 38.7 10.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP09411.1 - 2e-09 36.9 11.1 3.6e-09 36.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP09411.1 - 2.8e-08 33.2 13.9 5.4e-08 32.3 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP09411.1 - 6.4e-07 28.9 13.9 1.2e-06 28.0 9.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEP09411.1 - 2.1e-05 24.2 10.9 4.9e-05 23.1 7.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP09411.1 - 0.00072 19.2 10.8 0.0032 17.1 7.5 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CEP09411.1 - 0.13 12.4 10.1 0.46 10.6 7.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger TerY-C PF15616.1 CEP09411.1 - 0.79 9.6 8.1 2 8.3 5.6 1.6 1 0 0 1 1 1 0 TerY-C metal binding domain Prok-RING_4 PF14447.1 CEP09411.1 - 0.99 9.0 15.9 41 3.8 11.0 2.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF605 PF04652.11 CEP09411.1 - 2.8 7.2 24.9 5.4 6.3 17.3 1.4 1 0 0 1 1 1 0 Vta1 like zf-Nse PF11789.3 CEP09411.1 - 4.5 6.8 13.2 0.92 9.0 6.4 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-H2C2_2 PF13465.1 CEP09412.1 - 1.5e-17 62.9 11.9 2.6e-09 36.8 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEP09412.1 - 6.8e-14 51.2 20.7 2.1e-05 24.5 0.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP09412.1 - 2.4e-10 40.0 18.2 0.00023 21.2 0.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP09412.1 - 9.7e-07 28.4 11.3 0.00058 19.6 0.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP09412.1 - 0.0044 17.1 11.6 0.92 9.7 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 CEP09412.1 - 0.0047 16.8 6.8 0.36 10.8 2.9 3.1 2 1 0 2 2 2 1 Zinc ribbon domain zf-C2HC_2 PF13913.1 CEP09412.1 - 0.012 15.2 0.2 0.012 15.2 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-LYAR PF08790.6 CEP09412.1 - 0.013 15.2 7.6 0.25 11.0 0.2 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger C1_1 PF00130.17 CEP09412.1 - 0.013 15.2 2.4 0.065 12.9 0.1 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Herpes_BLRF2 PF05812.7 CEP09412.1 - 0.022 14.5 0.2 0.054 13.3 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Zn_Tnp_IS1595 PF12760.2 CEP09412.1 - 0.093 12.5 8.0 0.12 12.1 2.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 CEP09412.1 - 0.096 12.7 11.1 2.4 8.2 7.0 2.8 1 1 0 1 1 1 0 TFIIH C1-like domain Rad50_zn_hook PF04423.9 CEP09412.1 - 0.1 12.1 1.0 0.16 11.4 0.1 1.8 2 0 0 2 2 1 0 Rad50 zinc hook motif zf-met PF12874.2 CEP09412.1 - 0.14 12.4 12.0 0.15 12.2 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CEP09412.1 - 0.14 12.2 12.8 3.3 7.8 1.5 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SprT-like PF10263.4 CEP09412.1 - 0.18 11.4 6.5 0.45 10.1 3.2 2.2 1 1 1 2 2 2 0 SprT-like family zinc-ribbons_6 PF07191.7 CEP09412.1 - 1.3 8.8 6.9 27 4.6 2.0 3.0 2 1 0 2 2 2 0 zinc-ribbons zf-H2C2_5 PF13909.1 CEP09412.1 - 1.5 9.1 16.3 3.8 7.9 1.1 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DZR PF12773.2 CEP09412.1 - 3.4 7.5 8.2 1.6e+02 2.2 5.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 CEP09412.1 - 4 7.1 6.7 20 4.9 4.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIS_C PF01096.13 CEP09412.1 - 4.9 6.8 8.9 11 5.7 2.6 3.1 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) zf-AN1 PF01428.11 CEP09412.1 - 5 7.0 14.2 14 5.6 1.4 3.6 1 1 2 3 3 3 0 AN1-like Zinc finger PX PF00787.19 CEP09413.1 - 4.9e-22 77.8 0.4 1.1e-21 76.7 0.3 1.5 1 0 0 1 1 1 1 PX domain DUF2981 PF11200.3 CEP09413.1 - 0.32 10.0 4.3 0.63 9.0 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) ATP-synt_ab PF00006.20 CEP09414.1 - 2.6e-69 233.0 0.0 3.7e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEP09414.1 - 1.2e-25 90.2 0.0 3e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEP09414.1 - 6.7e-21 74.2 0.6 1.9e-20 72.8 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CEP09414.1 - 2.9e-05 23.8 0.2 9.8e-05 22.1 0.1 2.0 2 1 0 2 2 2 1 HAS barrel domain SNARE PF05739.14 CEP09415.1 - 5.8e-08 32.3 1.4 8.1e-08 31.8 1.0 1.2 1 0 0 1 1 1 1 SNARE domain Fijivirus_P9-2 PF06837.6 CEP09415.1 - 0.14 11.2 1.6 0.35 9.9 0.1 1.9 2 0 0 2 2 2 0 Fijivirus P9-2 protein PIG-F PF06699.6 CEP09415.1 - 0.15 12.0 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F TM231 PF10149.4 CEP09415.1 - 0.18 10.7 0.8 2.2 7.1 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 231 tRNA_bind PF01588.15 CEP09417.1 - 2.4e-25 88.2 0.0 5.3e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain PBP PF01161.15 CEP09417.1 - 2.9e-23 82.3 0.2 6.6e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pex14_N PF04695.8 CEP09418.1 - 1.4e-26 93.1 0.1 1.4e-26 93.1 0.1 3.0 3 0 0 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region TBCA PF02970.11 CEP09418.1 - 0.06 13.4 1.1 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A Ras PF00071.17 CEP09419.1 - 3.3e-52 176.1 0.2 4e-52 175.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP09419.1 - 5.8e-18 65.5 0.0 1e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP09419.1 - 1.5e-15 56.8 0.0 1.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP09419.1 - 2.6e-08 33.3 0.1 3.4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP09419.1 - 1.9e-07 30.7 0.2 1.6e-06 27.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP09419.1 - 4.9e-06 26.4 0.0 8.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CEP09419.1 - 0.00037 20.6 0.1 0.0011 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 CEP09419.1 - 0.004 16.3 0.0 0.0069 15.6 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CEP09419.1 - 0.015 14.4 0.0 0.043 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AIG1 PF04548.11 CEP09419.1 - 0.034 13.2 0.1 0.067 12.2 0.0 1.6 2 0 0 2 2 2 0 AIG1 family cobW PF02492.14 CEP09419.1 - 0.052 12.9 0.1 9.8 5.5 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 CEP09419.1 - 0.066 11.8 2.1 4.7 5.7 0.3 2.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.1 CEP09419.1 - 0.071 12.6 0.4 0.12 11.9 0.3 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CEP09419.1 - 0.078 12.2 0.1 4.1 6.6 0.1 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B SCP1201-deam PF14428.1 CEP09419.1 - 0.092 12.4 0.3 0.32 10.6 0.1 1.7 2 0 0 2 2 2 0 SCP1.201-like deaminase AAA_16 PF13191.1 CEP09419.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 CEP09419.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NTPase MFS_1 PF07690.11 CEP09420.1 - 4.5e-40 137.4 14.1 2.6e-20 72.4 0.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP09420.1 - 2.4e-06 26.2 12.2 7.5e-06 24.6 6.1 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 CEP09420.1 - 0.00024 19.8 14.9 0.00072 18.2 5.0 3.1 1 1 0 2 2 2 2 Sugar (and other) transporter FPN1 PF06963.7 CEP09420.1 - 0.0047 15.3 0.8 0.0047 15.3 0.6 1.7 2 0 0 2 2 2 1 Ferroportin1 (FPN1) MFS_1_like PF12832.2 CEP09420.1 - 0.0051 16.5 0.1 0.0051 16.5 0.1 2.3 3 0 0 3 3 3 1 MFS_1 like family 7tm_1 PF00001.16 CEP09420.1 - 0.019 14.0 3.9 1.6 7.8 0.1 2.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) YMF19 PF02326.10 CEP09420.1 - 0.045 14.3 0.7 0.23 12.0 0.6 2.0 2 0 0 2 2 2 0 Plant ATP synthase F0 OATP PF03137.15 CEP09420.1 - 0.21 9.6 6.7 1.7 6.6 0.3 2.8 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Mito_carr PF00153.22 CEP09421.1 - 1.9e-58 194.1 1.0 3.5e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ubiquitin PF00240.18 CEP09423.1 - 4.4e-12 45.2 0.0 1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CEP09423.1 - 7.9e-10 38.2 0.8 2e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 CEP09423.1 - 7.7e-07 28.7 0.1 1.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CEP09423.1 - 0.00019 21.2 0.1 0.00019 21.2 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEP09423.1 - 0.00037 20.6 1.8 0.00054 20.1 0.0 2.2 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain CUE PF02845.11 CEP09423.1 - 0.021 14.3 0.0 0.071 12.6 0.0 2.0 2 0 0 2 2 2 0 CUE domain DUF543 PF04418.7 CEP09425.1 - 2e-23 82.1 0.0 2.2e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) 2TM PF13239.1 CEP09425.1 - 0.00056 19.9 0.1 0.0009 19.2 0.0 1.3 1 1 0 1 1 1 1 2TM domain Sugar_tr PF00083.19 CEP09426.1 - 2.3e-91 306.6 40.9 5e-90 302.2 28.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP09426.1 - 2.1e-27 95.7 42.6 3.3e-18 65.5 12.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily COX7C PF02935.11 CEP09426.1 - 0.19 11.5 1.3 0.54 10.0 0.9 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Pkinase PF00069.20 CEP09427.1 - 1.8e-72 243.5 0.0 2.9e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09427.1 - 1.4e-37 129.1 0.0 1.8e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP09427.1 - 2.9e-08 33.0 0.0 5.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Helicase_C PF00271.26 CEP09428.1 - 2.9e-08 33.4 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cpn60_TCP1 PF00118.19 CEP09429.1 - 5.8e-138 460.5 10.9 6.9e-138 460.2 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3271 PF11675.3 CEP09429.1 - 0.039 13.0 0.2 0.07 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) SNF5 PF04855.7 CEP09430.1 - 3e-75 252.8 3.3 3e-75 252.8 2.3 2.2 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Cyclin_N PF00134.18 CEP09432.1 - 1.2e-36 125.0 0.2 1.3e-34 118.4 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CEP09432.1 - 1.2e-26 92.9 0.1 2.4e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Got1 PF04178.7 CEP09433.1 - 2.9e-24 85.4 8.3 4.4e-24 84.8 5.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Bromodomain PF00439.20 CEP09434.1 - 8.7e-18 64.0 0.2 2.5e-17 62.5 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.20 CEP09434.1 - 3.2e-10 39.5 0.1 9.9e-09 34.7 0.1 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09434.1 - 0.1 11.6 0.1 2.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase EI24 PF07264.6 CEP09435.1 - 3.8e-06 26.4 3.2 7.8e-06 25.4 2.2 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Pyr_redox_3 PF13738.1 CEP09436.1 - 4.1e-20 72.7 0.0 9.6e-20 71.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEP09436.1 - 2.5e-13 49.0 0.1 9.9e-13 47.1 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CEP09436.1 - 1.3e-10 40.7 0.5 3.3e-08 32.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEP09436.1 - 6.5e-10 38.9 0.0 2e-08 34.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP09436.1 - 2e-05 24.5 0.0 0.031 14.1 0.0 2.8 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP09436.1 - 0.0048 16.6 0.3 1.5 8.5 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 CEP09436.1 - 0.0049 16.0 0.4 0.056 12.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 CEP09436.1 - 0.01 16.2 0.2 10 6.6 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP09436.1 - 0.014 14.2 0.0 0.66 8.8 0.0 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 CEP09436.1 - 0.075 11.8 0.2 0.22 10.3 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 CEP09436.1 - 0.09 11.2 0.7 0.25 9.7 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 CEP09436.1 - 0.096 11.5 0.3 0.18 10.6 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain HATPase_c PF02518.21 CEP09437.1 - 1.1e-29 102.4 0.1 1.1e-28 99.2 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEP09437.1 - 5.7e-24 84.2 1.6 2.4e-20 72.5 1.1 2.5 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CEP09437.1 - 7e-15 54.7 2.6 1.4e-14 53.8 0.9 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain SNF2_N PF00176.18 CEP09438.1 - 2e-65 220.5 0.8 2e-65 220.5 0.6 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP09438.1 - 1.6e-11 43.8 0.0 6.2e-11 42.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_3 PF12836.2 CEP09438.1 - 0.00064 19.6 0.0 0.0022 17.8 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif UPF0052 PF01933.13 CEP09438.1 - 0.0066 15.8 0.3 0.016 14.5 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 WD40 PF00400.27 CEP09439.1 - 1.2e-25 88.4 7.8 3.2e-07 29.9 0.0 7.9 6 2 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 CEP09439.1 - 0.039 14.2 0.0 0.71 10.2 0.0 3.0 2 1 1 3 3 3 0 PQQ-like domain PBP1_TM PF14812.1 CEP09439.1 - 0.77 10.1 11.9 0.91 9.8 7.1 2.0 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hexokinase_2 PF03727.11 CEP09440.1 - 3.9e-52 176.8 0.0 5e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEP09440.1 - 2.4e-48 164.1 0.0 3.5e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Cu-oxidase_2 PF07731.9 CEP09441.1 - 3.3e-43 146.4 7.5 9.4e-41 138.5 0.1 3.7 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CEP09441.1 - 9.5e-41 138.2 11.3 2.8e-39 133.4 1.3 4.0 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 CEP09441.1 - 2.1e-32 112.2 2.5 4e-29 101.5 0.2 3.9 4 0 0 4 4 4 2 Multicopper oxidase FTR1 PF03239.9 CEP09442.1 - 1e-71 241.4 14.2 1.2e-71 241.1 9.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Mit_proteolip PF08039.6 CEP09442.1 - 0.027 14.4 0.3 0.092 12.7 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial proteolipid YfhO PF09586.5 CEP09442.1 - 0.05 11.6 6.7 0.5 8.3 0.1 2.7 3 0 0 3 3 3 0 Bacterial membrane protein YfhO PrgI PF12666.2 CEP09442.1 - 0.054 13.6 0.4 0.054 13.6 0.3 3.6 4 1 0 4 4 4 0 PrgI family protein ATP-synt_8 PF00895.15 CEP09442.1 - 1.2 9.4 3.6 21 5.3 0.0 3.8 4 0 0 4 4 4 0 ATP synthase protein 8 Wzy_C PF04932.10 CEP09442.1 - 3.1 7.5 16.3 0.081 12.7 3.1 2.6 2 1 0 2 2 2 0 O-Antigen ligase LRR_4 PF12799.2 CEP09443.1 - 0.0094 15.5 7.4 1.7 8.3 0.2 4.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) zf-CCHC PF00098.18 CEP09444.1 - 4.1e-06 26.4 18.7 4.4e-05 23.1 3.4 2.4 2 0 0 2 2 2 2 Zinc knuckle DUF4559 PF15112.1 CEP09444.1 - 0.61 9.1 8.9 0.29 10.2 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) RVT_1 PF00078.22 CEP09445.1 - 8.1e-27 93.9 0.5 2.7e-26 92.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP09445.1 - 1.1e-08 34.6 0.3 3.7e-08 33.0 0.2 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP09445.1 - 1.7e-05 24.8 0.3 3.5e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CEP09445.1 - 0.00065 19.9 1.1 0.0023 18.1 0.8 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Auxin_canalis PF05703.6 CEP09448.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.3 1 1 0 1 1 1 0 Auxin canalisation E1-E2_ATPase PF00122.15 CEP09449.1 - 3.9e-68 228.9 5.1 3.9e-68 228.9 3.6 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP09449.1 - 8.8e-42 142.6 0.8 8.8e-42 142.6 0.6 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP09449.1 - 6.5e-26 92.0 0.0 1.6e-24 87.5 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP09449.1 - 1.5e-19 69.7 0.1 4.4e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP09449.1 - 1.7e-15 57.7 0.0 3.9e-15 56.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP09449.1 - 3.9e-15 55.0 0.4 1.1e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP09449.1 - 0.0035 16.9 0.5 0.0035 16.9 0.4 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase zf-CCHC PF00098.18 CEP09450.1 - 4.5e-10 38.9 9.7 2e-05 24.2 1.1 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 CEP09450.1 - 1.6e-08 34.0 0.2 2.9e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CEP09450.1 - 5.5e-06 25.9 0.2 1.6e-05 24.3 0.2 1.8 1 0 0 1 1 1 1 KH domain zf-CCHC_2 PF13696.1 CEP09450.1 - 0.0077 15.7 0.2 0.0077 15.7 0.2 2.7 2 1 1 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.1 CEP09450.1 - 0.0094 15.6 9.0 0.056 13.1 0.9 2.8 2 1 1 3 3 3 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CEP09450.1 - 0.041 13.9 6.2 0.086 12.9 4.3 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_6 PF15288.1 CEP09450.1 - 0.041 13.5 9.3 0.22 11.2 0.3 2.8 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEP09450.1 - 0.25 11.0 10.1 1.6 8.4 1.3 2.7 3 0 0 3 3 3 0 Zinc knuckle REV PF00424.13 CEP09450.1 - 0.39 10.6 5.5 3.1 7.7 0.3 2.9 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) BTB_2 PF02214.17 CEP09451.1 - 4.2e-11 42.9 0.0 7.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CX PF01705.14 CEP09451.1 - 0.014 15.3 0.6 0.25 11.3 0.1 2.6 1 1 1 2 2 2 0 CX module BTB_2 PF02214.17 CEP09452.1 - 1.9e-15 56.8 0.2 3.4e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CEP09452.1 - 0.0099 15.8 0.4 0.017 15.1 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain IPK PF03770.11 CEP09454.1 - 3e-51 173.8 0.0 5.4e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1661 PF07877.6 CEP09454.1 - 0.071 12.6 0.1 0.19 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) Coatomer_WDAD PF04053.9 CEP09455.1 - 3e-170 566.8 0.0 9.1e-169 561.9 0.0 2.4 3 0 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 CEP09455.1 - 2e-54 179.6 4.8 1.8e-11 43.4 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CEP09455.1 - 6.3e-06 25.9 0.0 1.4 8.7 0.0 5.0 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Clathrin PF00637.15 CEP09455.1 - 0.074 12.6 0.0 11 5.6 0.0 2.4 1 1 1 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.3 CEP09455.1 - 0.21 9.7 3.1 12 3.9 0.2 3.6 3 1 0 3 3 3 0 Nucleoporin Nup120/160 COMPASS-Shg1 PF05205.7 CEP09456.1 - 3.5e-13 49.7 1.7 4.2e-13 49.4 1.2 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Fungal_trans PF04082.13 CEP09457.1 - 1.6e-34 118.9 0.5 5e-34 117.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain SOXp PF12336.3 CEP09457.1 - 7.1 7.3 8.8 29 5.3 6.1 2.1 1 0 0 1 1 1 0 SOX transcription factor Far-17a_AIG1 PF04750.9 CEP09458.1 - 1.7e-05 24.1 24.5 2.7e-05 23.4 17.0 1.4 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3382 PF11862.3 CEP09458.1 - 0.08 12.8 3.6 0.083 12.8 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) p53-inducible11 PF14936.1 CEP09458.1 - 8.1 6.3 8.0 11 5.8 5.5 1.3 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 FA_desaturase PF00487.19 CEP09458.1 - 9 5.6 16.2 43 3.4 11.2 1.9 1 1 0 1 1 1 0 Fatty acid desaturase Helitron_like_N PF14214.1 CEP09459.1 - 2e-13 50.4 0.0 2.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.1 CEP09460.1 - 2.2e-48 164.4 0.0 3.4e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Chromo PF00385.19 CEP09463.1 - 5.2e-17 61.2 0.1 7.9e-17 60.6 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP09463.1 - 0.0086 15.7 0.1 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DDE_3 PF13358.1 CEP09464.1 - 2.2e-13 50.1 0.6 2.5e-13 50.0 0.4 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_A_exo1 PF01612.15 CEP09468.1 - 5.5e-07 29.2 0.0 9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCHC_4 PF14392.1 CEP09470.1 - 0.026 14.1 8.3 0.93 9.2 0.5 2.7 2 0 0 2 2 2 0 Zinc knuckle GFA PF04828.9 CEP09470.1 - 0.57 10.1 5.7 4.8 7.2 1.0 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-BED PF02892.10 CEP09470.1 - 0.99 9.2 7.5 2.7 7.8 0.7 3.1 3 0 0 3 3 3 0 BED zinc finger zf-CCHC PF00098.18 CEP09470.1 - 6.2 6.9 14.5 0.22 11.5 0.7 3.3 4 0 0 4 4 4 0 Zinc knuckle PIF1 PF05970.9 CEP09471.1 - 1.2e-22 80.4 0.0 1.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 CEP09471.1 - 0.0014 18.2 0.2 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CEP09471.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CEP09471.1 - 0.015 14.2 0.2 0.025 13.5 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 CEP09471.1 - 0.031 12.8 0.0 0.045 12.3 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 CEP09471.1 - 0.048 13.6 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 CEP09471.1 - 0.065 12.9 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 CEP09471.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.1 CEP09471.1 - 0.14 12.9 0.1 0.39 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 CEP09472.1 - 2.9e-35 121.9 0.0 6.3e-17 61.5 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 CEP09472.1 - 0.003 15.4 0.0 0.004 14.9 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP09472.1 - 0.095 12.8 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 CEP09473.1 - 1.9e-06 27.0 0.0 2.1e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase DDE_3 PF13358.1 CEP09474.1 - 6.9e-28 97.2 0.0 1.3e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP09474.1 - 2.6e-07 30.7 0.0 4.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP09474.1 - 0.019 14.9 0.1 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.2 CEP09474.1 - 0.038 14.2 0.4 6.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Retrotrans_gag PF03732.12 CEP09479.1 - 1e-05 25.5 0.4 3.4e-05 23.8 0.3 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein TerB PF05099.8 CEP09479.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TerB UBN2_2 PF14227.1 CEP09479.1 - 0.033 13.7 0.1 0.092 12.3 0.1 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type SR-25 PF10500.4 CEP09479.1 - 0.046 13.2 3.0 0.069 12.6 2.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UBN2 PF14223.1 CEP09479.1 - 0.067 12.9 0.4 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RabGAP-TBC PF00566.13 CEP09480.1 - 0.17 11.3 0.1 0.84 9.0 0.1 2.0 1 1 0 1 1 1 0 Rab-GTPase-TBC domain CPSF_A PF03178.10 CEP09481.1 - 7.6e-43 146.8 0.2 3.9e-41 141.1 0.1 2.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CEP09481.1 - 5e-38 130.4 2.5 9.9e-38 129.5 1.7 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term MAP65_ASE1 PF03999.7 CEP09481.1 - 6.6e-13 48.1 33.0 4.7e-12 45.3 22.9 1.9 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) RR_TM4-6 PF06459.7 CEP09481.1 - 0.047 13.5 8.2 0.077 12.8 5.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDE_3 PF13358.1 CEP09482.1 - 1.2e-15 57.5 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3429 PF11911.3 CEP09483.1 - 0.11 12.4 4.4 0.19 11.6 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3429) Kinesin PF00225.18 CEP09485.1 - 8.1e-106 353.5 1.1 8.1e-106 353.5 0.8 3.0 3 2 0 3 3 3 1 Kinesin motor domain MFS_1 PF07690.11 CEP09487.1 - 1e-36 126.4 16.9 1e-36 126.4 11.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP09487.1 - 1.5e-08 33.6 21.7 2.3e-08 33.0 2.0 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter RasGEF PF00617.14 CEP09488.1 - 6.7e-62 208.5 0.4 1.7e-61 207.2 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEP09488.1 - 4.6e-29 100.5 1.2 2.1e-28 98.4 0.2 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 CEP09488.1 - 4.1e-14 51.7 0.0 8.1e-14 50.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP09488.1 - 1e-10 40.9 0.1 2e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP09488.1 - 5.8e-10 38.5 0.0 1.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Uds1 PF15456.1 CEP09489.1 - 0.098 12.6 3.4 0.2 11.6 2.3 1.5 1 0 0 1 1 1 0 Up-regulated During Septation SIT PF15330.1 CEP09489.1 - 0.14 12.3 0.6 0.25 11.5 0.1 1.6 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT AATF-Che1 PF13339.1 CEP09489.1 - 0.15 12.2 4.8 0.084 13.0 1.3 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor KxDL PF10241.4 CEP09489.1 - 0.22 11.4 2.5 0.4 10.6 1.7 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein IncA PF04156.9 CEP09489.1 - 0.39 10.2 3.6 0.46 10.0 2.5 1.1 1 0 0 1 1 1 0 IncA protein AKNA PF12443.3 CEP09489.1 - 3 7.9 6.8 0.23 11.4 0.5 2.1 2 1 0 2 2 2 0 AT-hook-containing transcription factor AATF-Che1 PF13339.1 CEP09490.1 - 7.5e-28 97.3 1.3 7.5e-28 97.3 0.9 3.2 3 2 1 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 CEP09490.1 - 9.8e-26 89.6 0.2 9.8e-26 89.6 0.2 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Apolipo_F PF15148.1 CEP09490.1 - 0.00072 18.9 0.7 0.0014 17.9 0.5 1.5 1 0 0 1 1 1 1 Apolipoprotein F PBP1_TM PF14812.1 CEP09491.1 - 0.35 11.2 3.8 0.48 10.7 0.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LON PF02190.11 CEP09492.1 - 2.5e-19 69.7 0.0 3.6e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 CEP09492.1 - 1.3e-08 34.5 24.4 4.1e-06 26.5 6.0 2.4 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CEP09492.1 - 3.1e-05 23.9 25.8 0.0043 17.0 7.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP09492.1 - 5.4e-05 22.8 23.6 0.00031 20.4 6.6 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 CEP09492.1 - 9.6e-05 21.9 20.6 0.0022 17.5 7.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP09492.1 - 0.00023 20.7 21.0 0.0034 17.0 5.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP09492.1 - 0.0094 15.7 23.7 0.095 12.5 6.3 2.5 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.1 CEP09492.1 - 0.017 14.6 8.9 0.039 13.5 0.2 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 CEP09492.1 - 0.24 11.1 13.0 0.68 9.6 2.0 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 CEP09492.1 - 0.5 10.1 16.0 0.35 10.6 1.9 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein XPG_I_2 PF12813.2 CEP09493.1 - 7.4e-17 61.6 0.4 3.9e-13 49.4 0.0 2.6 3 0 0 3 3 3 2 XPG domain containing XPG_N PF00752.12 CEP09493.1 - 3e-07 30.6 0.0 1.2e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CEP09493.1 - 0.015 15.3 0.0 0.048 13.7 0.0 2.0 1 0 0 1 1 1 0 XPG I-region Pox_H7 PF04787.7 CEP09493.1 - 0.17 11.6 4.2 1.6 8.5 0.2 2.6 2 0 0 2 2 2 0 Late protein H7 DnaJ PF00226.26 CEP09494.1 - 2.1e-14 52.9 1.2 3.9e-14 52.1 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain Oxysterol_BP PF01237.13 CEP09495.1 - 4.5e-113 377.3 2.7 4.5e-113 377.3 1.9 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 CEP09495.1 - 1.1e-20 73.5 0.2 2.9e-20 72.1 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CEP09495.1 - 4.7e-08 33.2 10.7 3.7e-06 27.1 0.1 4.1 4 1 1 5 5 5 2 Pleckstrin homology domain PH PF00169.24 CEP09495.1 - 4.9e-07 29.8 4.2 1.4e-06 28.3 0.1 3.5 4 0 0 4 4 4 1 PH domain GOLD_2 PF13897.1 CEP09495.1 - 0.023 14.8 0.2 0.33 11.1 0.0 2.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking EF-hand_1 PF00036.27 CEP09496.1 - 1.4e-25 86.5 6.8 1e-06 27.5 0.1 5.8 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 CEP09496.1 - 1.9e-23 80.1 3.4 0.00017 21.1 0.0 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 CEP09496.1 - 3.3e-23 81.5 1.0 5.6e-10 39.2 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CEP09496.1 - 1.9e-22 77.5 1.4 0.0001 21.4 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CEP09496.1 - 1.7e-19 69.1 6.2 1.5e-10 40.4 0.0 4.9 3 2 2 5 5 5 5 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CEP09496.1 - 0.12 12.4 1.7 2.6 8.1 0.5 2.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF605 PF04652.11 CEP09496.1 - 3.4 6.9 10.7 4.5 6.5 7.4 1.1 1 0 0 1 1 1 0 Vta1 like EF-hand_1 PF00036.27 CEP09497.1 - 1.5e-23 80.2 1.8 1.2e-05 24.2 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CEP09497.1 - 5e-20 69.5 0.8 9.7e-05 21.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CEP09497.1 - 4.1e-18 65.2 3.4 3.2e-09 36.7 0.4 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CEP09497.1 - 1.8e-13 49.1 3.9 0.00072 18.7 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CEP09497.1 - 6.1e-12 44.9 5.3 8.9e-07 28.4 0.0 4.3 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CEP09497.1 - 0.046 13.7 0.6 0.76 9.8 0.3 2.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEP09497.1 - 0.073 12.8 0.3 0.24 11.1 0.1 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 CEP09497.1 - 0.15 11.7 1.6 11 5.7 0.0 3.3 3 1 1 4 4 4 0 EF hand Ank_2 PF12796.2 CEP09498.1 - 1.1e-50 169.8 16.3 6e-16 58.5 0.2 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP09498.1 - 2.2e-32 110.3 11.4 2.5e-06 27.5 0.1 6.5 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 CEP09498.1 - 4.4e-32 108.2 13.4 0.00051 19.7 0.1 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 CEP09498.1 - 4.4e-31 106.6 9.3 6.3e-08 32.9 0.0 6.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP09498.1 - 5.9e-29 97.2 11.8 0.00024 21.0 0.0 7.9 8 0 0 8 8 8 7 Ankyrin repeat Plant_tran PF04827.9 CEP09498.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein Ribosomal_L37ae PF01780.14 CEP09499.1 - 1e-40 137.4 11.3 1.1e-40 137.3 7.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 CEP09499.1 - 0.00066 19.4 2.3 0.00096 18.9 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CEP09499.1 - 0.0012 18.1 3.3 0.55 9.7 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 CEP09499.1 - 0.016 14.8 2.6 0.3 10.7 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif OrfB_Zn_ribbon PF07282.6 CEP09499.1 - 0.075 12.6 1.5 0.11 12.2 1.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.1 CEP09499.1 - 0.092 13.0 2.0 1.7 9.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 CEP09499.1 - 0.15 12.0 2.0 0.78 9.7 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 CEP09499.1 - 0.22 11.0 0.9 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Elf1 PF05129.8 CEP09499.1 - 0.23 11.1 3.0 0.41 10.3 2.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 CEP09499.1 - 0.26 11.0 6.2 0.25 11.1 0.6 2.3 1 1 1 2 2 2 0 BED zinc finger C1_1 PF00130.17 CEP09499.1 - 0.34 10.6 2.9 0.49 10.1 2.0 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CarbpepA_inh PF02977.10 CEP09499.1 - 1.7 8.2 5.4 8.5 6.0 3.7 2.0 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 CEP09499.1 - 2.3 8.7 4.5 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L29 PF00831.18 CEP09500.1 - 6.9e-14 51.2 3.2 6.9e-14 51.2 2.2 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein CCDC14 PF15254.1 CEP09500.1 - 0.0094 14.3 4.0 0.011 14.2 2.5 1.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 14 Ribosomal_S9 PF00380.14 CEP09500.1 - 0.025 14.8 5.1 0.036 14.3 3.5 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 CENP-B_N PF04218.8 CEP09500.1 - 1.5 8.3 5.1 12 5.4 0.1 3.1 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain LTXXQ PF07813.7 CEP09500.1 - 5.3 7.5 7.9 30 5.1 0.9 2.3 1 1 0 2 2 2 0 LTXXQ motif family protein HMG_box PF00505.14 CEP09501.1 - 3.8e-14 52.6 1.1 7.9e-14 51.6 0.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP09501.1 - 1.1e-07 32.1 0.8 2.5e-07 30.9 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain DUF1977 PF09320.6 CEP09501.1 - 0.022 14.9 2.0 0.056 13.6 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) HSP90 PF00183.13 CEP09503.1 - 2.8e-257 854.3 31.5 3.3e-257 854.1 21.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CEP09503.1 - 2e-12 46.8 0.0 4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CEP09503.1 - 3.9e-11 42.7 0.1 3.9e-11 42.7 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NAD_binding_5 PF07994.7 CEP09503.1 - 3.4 7.0 7.7 4.6 6.6 3.1 2.2 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase WD40 PF00400.27 CEP09507.1 - 2.3e-54 179.4 16.8 4.5e-10 39.0 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CEP09507.1 - 8.6e-13 47.2 15.8 1.7e-05 23.1 0.0 6.4 2 1 4 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP09507.1 - 6e-11 41.8 0.8 1.3e-10 40.7 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP09507.1 - 7.2e-07 28.7 0.3 1.9e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CEP09507.1 - 1.5e-06 27.8 0.0 2.1e-05 24.0 0.0 2.6 1 1 1 2 2 2 2 PQQ-like domain Hira PF07569.6 CEP09507.1 - 0.053 12.7 0.2 4 6.5 0.0 3.4 2 1 1 3 3 3 0 TUP1-like enhancer of split DUF1513 PF07433.6 CEP09507.1 - 0.089 11.6 0.0 3.5 6.4 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) Macoilin PF09726.4 CEP09507.1 - 1.8 6.7 6.9 2.5 6.2 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Radical_SAM PF04055.16 CEP09508.1 - 5.8e-11 42.8 0.0 4.9e-10 39.8 0.0 2.6 2 1 0 2 2 2 1 Radical SAM superfamily Nup35_RRM PF05172.8 CEP09508.1 - 1e-09 38.0 2.0 1.5e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CEP09508.1 - 1.1e-05 25.1 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Fer4_14 PF13394.1 CEP09508.1 - 4.4e-05 23.4 0.4 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 CEP09508.1 - 0.016 15.3 0.0 0.06 13.4 0.0 2.0 1 0 0 1 1 1 0 4Fe-4S single cluster domain RAB3GAP2_N PF14655.1 CEP09508.1 - 0.023 13.7 2.6 0.036 13.0 1.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_FG PF13634.1 CEP09508.1 - 0.062 13.5 69.3 0.053 13.7 34.1 3.5 2 1 1 3 3 3 0 Nucleoporin FG repeat region zf-C2H2 PF00096.21 CEP09509.1 - 1.6e-10 40.7 10.6 7.8e-07 29.0 0.8 5.5 7 0 0 7 7 7 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP09509.1 - 2.3e-07 30.7 2.8 2.3e-07 30.7 1.9 5.1 6 0 0 6 6 6 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP09509.1 - 2.9e-07 30.3 9.0 0.00022 21.3 1.7 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 CEP09509.1 - 0.00094 19.2 6.0 0.18 12.0 1.2 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type CHORD PF04968.7 CEP09509.1 - 0.046 13.9 2.2 6.9 6.9 0.0 3.2 2 0 0 2 2 2 0 CHORD zf-BED PF02892.10 CEP09509.1 - 0.21 11.3 7.3 1.8 8.4 0.9 3.0 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_jaz PF12171.3 CEP09509.1 - 2.4 8.4 14.7 1.5 9.0 0.3 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HMG_box PF00505.14 CEP09510.1 - 1.2e-06 28.6 0.1 1.2e-06 28.6 0.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP09510.1 - 4.7e-05 23.6 0.4 8.6e-05 22.8 0.2 1.5 1 1 0 1 1 1 1 HMG-box domain DUF1074 PF06382.6 CEP09510.1 - 0.014 15.3 0.2 0.026 14.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1074) Tox-MPTase4 PF15640.1 CEP09510.1 - 0.018 14.6 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 Metallopeptidase toxin 4 Tir_receptor_C PF07489.6 CEP09510.1 - 0.074 12.8 1.2 0.094 12.4 0.9 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus PH PF00169.24 CEP09512.1 - 5.2e-12 45.8 0.1 4.2e-10 39.7 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 CEP09512.1 - 4.4e-06 26.8 0.6 4.7e-05 23.5 0.0 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain LEA_2 PF03168.8 CEP09513.1 - 0.093 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein Vps52 PF04129.7 CEP09514.1 - 1.1e-134 449.7 9.9 1.6e-134 449.2 6.9 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 CEP09514.1 - 4.3e-06 25.1 14.6 1.1e-05 23.8 0.7 3.1 3 0 0 3 3 3 3 Exocyst complex component Sec3 COG2 PF06148.6 CEP09514.1 - 0.00068 19.5 3.2 0.0021 17.9 2.2 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 HAP1_N PF04849.8 CEP09514.1 - 0.054 12.4 11.3 0.094 11.6 7.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1722 PF08349.6 CEP09514.1 - 0.17 11.7 2.8 5.4 6.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) WD40 PF00400.27 CEP09515.1 - 0.012 15.4 1.5 1.4 8.9 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF1043 PF06295.7 CEP09515.1 - 0.13 11.8 3.6 0.23 11.1 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Herpes_BLLF1 PF05109.8 CEP09516.1 - 0.42 8.5 7.3 1.9 6.3 5.7 1.6 2 0 0 2 2 2 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-H2C2_2 PF13465.1 CEP09517.1 - 5.5e-12 45.3 16.0 1.3e-07 31.5 2.0 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP09517.1 - 6.9e-09 35.4 23.6 0.001 19.2 0.7 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP09517.1 - 1.4e-08 34.5 8.1 1.5e-06 28.1 0.3 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CEP09517.1 - 0.013 15.6 14.8 0.17 12.0 0.3 4.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEP09517.1 - 0.016 15.0 2.9 0.16 11.9 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Exo_endo_phos_2 PF14529.1 CEP09518.1 - 0.0004 19.9 0.4 0.0013 18.2 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP09518.1 - 0.0023 17.9 0.1 0.0041 17.0 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M9 PF01752.12 CEP09518.1 - 0.23 10.3 2.1 0.36 9.6 1.5 1.2 1 0 0 1 1 1 0 Collagenase PIF1 PF05970.9 CEP09519.1 - 1.1e-41 142.9 0.0 1.3e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 CEP09521.1 - 1.9e-45 154.8 0.0 2.2e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Cyclase_polyket PF04673.7 CEP09522.1 - 0.08 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Polyketide synthesis cyclase DUF3402 PF11882.3 CEP09526.1 - 0.049 12.6 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF3091 PF11291.3 CEP09526.1 - 0.12 12.3 0.4 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) BRF1 PF07741.8 CEP09526.1 - 0.15 12.2 2.6 0.22 11.7 1.8 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DDE_3 PF13358.1 CEP09528.1 - 6.2e-30 103.8 0.0 1e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP09528.1 - 5.9e-08 32.8 0.2 1.2e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP09528.1 - 3.9e-06 26.7 1.0 8.4e-06 25.6 0.7 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP09528.1 - 8.1e-05 23.3 0.5 0.0003 21.5 0.0 2.2 2 1 1 3 3 3 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CEP09528.1 - 0.01 14.9 0.0 0.023 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DDE_1 PF03184.14 CEP09528.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 DDE superfamily endonuclease MULE PF10551.4 CEP09528.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain HTH_23 PF13384.1 CEP09528.1 - 0.063 12.9 0.4 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain rve PF00665.21 CEP09528.1 - 0.072 13.2 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain Exo_endo_phos_2 PF14529.1 CEP09529.1 - 6.4e-09 35.4 0.1 1.8e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP09529.1 - 0.00097 19.1 2.5 0.0017 18.3 1.7 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PMBR PF09373.5 CEP09529.1 - 0.094 12.7 0.5 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat AAA_12 PF13087.1 CEP09529.1 - 0.11 11.9 3.3 0.76 9.1 2.3 2.0 1 1 0 1 1 1 0 AAA domain RVT_1 PF00078.22 CEP09530.1 - 2.8e-10 39.9 0.0 3.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_capsid PF05065.8 CEP09533.1 - 0.021 14.0 1.1 0.032 13.4 0.8 1.3 1 1 0 1 1 1 0 Phage capsid family Terminase_4 PF05119.7 CEP09535.1 - 0.048 13.8 0.0 0.084 13.0 0.0 1.4 1 1 0 1 1 1 0 Phage terminase, small subunit GIT_SHD PF08518.6 CEP09536.1 - 0.062 12.6 0.2 0.18 11.1 0.2 1.8 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Atg14 PF10186.4 CEP09539.1 - 0.09 11.7 0.3 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 QRPTase_N PF02749.11 CEP09539.1 - 0.19 11.5 3.0 11 5.9 0.3 2.3 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Phage_B PF02304.10 CEP09539.1 - 2 8.7 4.6 19 5.6 0.4 2.2 2 0 0 2 2 2 0 Scaffold protein B LRR_2 PF07723.8 CEP09541.1 - 0.013 15.9 7.1 0.8 10.3 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat F-box PF00646.28 CEP09541.1 - 0.028 14.0 2.6 0.032 13.9 0.1 2.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 CEP09541.1 - 0.19 11.4 6.5 0.036 13.7 0.8 2.6 3 0 0 3 3 3 0 F-box-like LRR_6 PF13516.1 CEP09541.1 - 0.67 10.2 7.7 2e+02 2.5 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich repeat LRR_4 PF12799.2 CEP09541.1 - 3.9 7.1 13.0 22 4.7 0.0 5.6 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) Baculo_PEP_N PF04512.7 CEP09543.1 - 0.08 12.9 0.2 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Pkinase PF00069.20 CEP09544.1 - 1.5e-67 227.5 0.0 2.7e-67 226.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09544.1 - 2.2e-34 118.7 0.0 3.8e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CEP09544.1 - 5.8e-18 64.3 31.9 9.8e-11 41.2 6.7 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 CEP09544.1 - 3.6e-14 52.2 6.9 1.1e-06 28.2 0.4 2.5 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 CEP09544.1 - 3.7e-09 36.9 0.2 1.3e-08 35.1 0.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEP09544.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.5 1 1 0 1 1 1 0 Kinase-like TFIIA PF03153.8 CEP09544.1 - 5.1 6.8 20.3 5.2 6.8 11.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit C1_2 PF03107.11 CEP09544.1 - 9.6 6.4 23.2 1.7 8.8 6.8 2.9 2 0 0 2 2 2 0 C1 domain DDE_Tnp_1_7 PF13843.1 CEP09545.1 - 0.0031 16.6 0.0 0.0033 16.5 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 RRM_1 PF00076.17 CEP09546.1 - 3e-40 135.7 0.0 3.8e-20 71.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP09546.1 - 2.9e-36 123.2 0.0 6.4e-17 61.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP09546.1 - 2.3e-17 62.5 0.0 4.6e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP09546.1 - 7.2e-06 25.6 0.0 0.0058 16.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif HSP90 PF00183.13 CEP09546.1 - 1.3 7.3 8.0 1.8 6.8 5.6 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 CEP09546.1 - 2.5 6.0 10.7 3.3 5.6 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CEP09546.1 - 4.5 6.5 14.3 6.5 6.0 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HSP70 PF00012.15 CEP09547.1 - 3.9e-06 25.0 0.4 0.00031 18.8 0.0 3.2 3 0 0 3 3 3 3 Hsp70 protein Rsm22 PF09243.5 CEP09548.1 - 1.2e-71 240.9 0.0 1.6e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.1 CEP09548.1 - 0.00015 21.3 0.0 0.00079 19.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP09548.1 - 0.00045 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP09548.1 - 0.0012 19.3 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP09548.1 - 0.004 17.4 0.0 0.014 15.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP09548.1 - 0.017 15.6 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CEP09548.1 - 0.066 12.3 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family HSP70 PF00012.15 CEP09549.1 - 9e-05 20.5 1.0 0.00023 19.2 0.1 2.0 3 0 0 3 3 3 1 Hsp70 protein DDE_3 PF13358.1 CEP09550.1 - 3.6e-17 62.4 0.0 6.1e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP09550.1 - 0.036 13.1 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF2098 PF09871.4 CEP09550.1 - 0.28 11.1 1.8 0.59 10.0 1.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Spectrin PF00435.16 CEP09550.1 - 0.43 10.8 3.3 0.2 11.9 0.5 1.7 2 0 0 2 2 2 0 Spectrin repeat VHS PF00790.14 CEP09551.1 - 5.9e-16 58.3 0.2 2.9e-14 52.8 0.3 2.7 2 2 1 3 3 3 1 VHS domain GAT PF03127.9 CEP09551.1 - 1.3e-15 57.2 0.2 1.3e-15 57.2 0.1 2.0 3 0 0 3 3 3 1 GAT domain DUF4075 PF13294.1 CEP09551.1 - 0.0084 16.1 0.1 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4075) AKAP95 PF04988.7 CEP09553.1 - 0.031 14.0 1.1 0.64 9.7 0.2 2.3 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DDE_3 PF13358.1 CEP09554.1 - 5.5e-23 81.3 0.1 4.1e-22 78.4 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 CEP09554.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain DUF3437 PF11919.3 CEP09555.1 - 5.4e-31 106.1 0.0 4.3e-30 103.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 CEP09555.1 - 0.00012 21.8 0.1 2.4 8.4 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 CEP09555.1 - 0.0018 18.5 0.0 0.1 12.8 0.0 3.6 2 1 1 3 3 3 1 HEAT repeats Ras PF00071.17 CEP09556.1 - 7.5e-53 178.2 0.0 8.6e-53 178.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP09556.1 - 9.1e-16 58.4 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP09556.1 - 1.2e-06 27.8 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Metallophos PF00149.23 CEP09557.1 - 1.5e-17 63.6 1.3 4.1e-10 39.3 0.3 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Nudix_N_2 PF14803.1 CEP09557.1 - 0.031 13.9 1.6 0.055 13.1 0.0 2.3 3 0 0 3 3 3 0 Nudix N-terminal DUF2321 PF10083.4 CEP09557.1 - 0.1 12.1 0.2 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Mannosyl_trans PF05007.8 CEP09558.1 - 2.4e-79 266.6 24.6 2.8e-77 259.8 16.1 2.5 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) MPC PF03650.8 CEP09558.1 - 1.1e-33 115.7 0.1 2.4e-33 114.5 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Myotub-related PF06602.9 CEP09559.1 - 2.7e-129 430.9 0.2 3.2e-129 430.7 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 CEP09559.1 - 0.0014 17.9 0.3 0.0042 16.4 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 CEP09559.1 - 0.023 14.2 0.1 0.079 12.5 0.0 1.8 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CEP09559.1 - 0.068 13.4 0.0 0.19 11.9 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family CYSTM PF12734.2 CEP09560.1 - 0.011 15.7 24.5 0.047 13.7 17.0 1.9 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Pdase_C33_assoc PF14756.1 CEP09560.1 - 0.11 12.2 1.9 0.11 12.1 1.3 1.1 1 0 0 1 1 1 0 Peptidase_C33-associated domain Sad1_UNC PF07738.8 CEP09561.1 - 1.8e-22 79.5 0.1 6.8e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Leu_zip PF15294.1 CEP09561.1 - 0.019 14.0 1.6 0.032 13.3 1.1 1.3 1 0 0 1 1 1 0 Leucine zipper IncA PF04156.9 CEP09561.1 - 0.026 14.1 0.8 0.058 12.9 0.6 1.6 1 0 0 1 1 1 0 IncA protein YebG PF07130.7 CEP09561.1 - 0.054 13.1 0.2 13 5.5 0.0 2.5 2 0 0 2 2 2 0 YebG protein Ribosomal_L28e PF01778.12 CEP09562.1 - 0.13 12.7 0.5 0.88 9.9 0.1 2.2 1 1 1 2 2 2 0 Ribosomal L28e protein family KAR9 PF08580.5 CEP09562.1 - 0.84 7.8 7.3 0.96 7.6 5.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RRM_1 PF00076.17 CEP09563.1 - 6e-14 51.4 0.1 1.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 CEP09563.1 - 2.1e-11 43.1 9.0 1.9e-06 27.5 1.7 2.4 2 0 0 2 2 2 2 Zinc knuckle RRM_5 PF13893.1 CEP09563.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP09563.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_6 PF15288.1 CEP09563.1 - 0.0031 17.1 5.3 0.26 11.0 0.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP09563.1 - 0.12 12.0 7.8 0.31 10.7 1.0 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF566 PF04484.7 CEP09563.1 - 4.5 6.6 21.5 6.8 6.1 14.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-CCHC_3 PF13917.1 CEP09563.1 - 4.9 6.9 8.1 5.6 6.7 0.0 2.8 3 0 0 3 3 3 0 Zinc knuckle Glucosamine_iso PF01182.15 CEP09564.1 - 1.9e-66 223.5 0.0 2.2e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FNIP_M PF14637.1 CEP09566.1 - 1.2e-56 191.9 0.1 2.7e-56 190.7 0.1 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 CEP09566.1 - 1.1e-25 90.1 0.4 4.7e-25 88.0 0.3 2.0 1 1 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 CEP09566.1 - 4.9e-13 49.6 0.0 4.9e-13 49.6 0.0 3.5 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus Actin PF00022.14 CEP09567.1 - 4.1e-142 473.2 0.0 4.7e-142 473.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CEP09567.1 - 8.1e-08 31.2 0.0 5.2e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Peptidase_M16 PF00675.15 CEP09568.1 - 6e-23 81.2 0.9 1e-22 80.4 0.6 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CEP09568.1 - 2.4e-20 72.9 0.0 5.9e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain CTP_transf_1 PF01148.15 CEP09570.1 - 1.5e-80 270.5 28.0 1.8e-80 270.3 19.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family CDP-OH_P_transf PF01066.16 CEP09571.1 - 1.8e-17 63.4 0.8 1.8e-17 63.4 0.5 2.4 4 0 0 4 4 4 1 CDP-alcohol phosphatidyltransferase Rpn3_C PF08375.6 CEP09572.1 - 5e-28 97.2 1.8 5e-28 97.2 1.3 2.8 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 CEP09572.1 - 4.1e-21 75.2 1.1 2.4e-20 72.7 0.0 2.8 4 0 0 4 4 4 1 PCI domain TPR_12 PF13424.1 CEP09572.1 - 0.0058 16.5 8.8 0.0082 16.0 3.6 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CEP09572.1 - 0.19 11.7 6.9 0.072 13.0 0.9 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.3 CEP09573.1 - 5.1e-06 26.4 3.4 1.5e-05 24.9 2.3 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP09573.1 - 4.2e-05 23.6 3.6 4.2e-05 23.6 2.5 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CEP09573.1 - 0.0017 18.3 2.3 0.01 15.9 0.2 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 CEP09573.1 - 0.0066 16.1 1.3 0.017 14.7 0.3 2.2 2 0 0 2 2 2 1 DBF zinc finger TIP120 PF08623.5 CEP09573.1 - 0.012 15.2 3.7 0.014 15.0 1.7 1.8 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) zf-C2H2 PF00096.21 CEP09573.1 - 0.083 13.2 2.7 0.28 11.5 1.9 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CEP09573.1 - 1.2 9.1 7.4 0.13 12.1 1.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger hNIFK_binding PF12196.3 CEP09574.1 - 0.0062 15.8 0.1 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK Syntaxin-6_N PF09177.6 CEP09574.1 - 0.25 11.7 3.1 0.96 9.8 0.2 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF1319 PF07028.6 CEP09574.1 - 1.4 9.1 5.9 2.4 8.3 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) Cytochrom_B562 PF07361.6 CEP09575.1 - 0.28 11.5 9.1 1.2 9.6 0.1 2.9 2 1 1 3 3 3 0 Cytochrome b562 zf-RVT PF13966.1 CEP09576.1 - 0.00086 19.5 0.5 0.002 18.3 0.3 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF726 PF05277.7 CEP09577.1 - 1.5e-119 398.9 0.1 2.4e-119 398.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 CEP09577.1 - 0.01 15.5 0.0 0.037 13.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP09577.1 - 0.03 14.2 0.1 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_1c PF00749.16 CEP09578.1 - 4.5e-104 347.5 0.0 6.2e-104 347.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CEP09578.1 - 7.2e-43 146.2 0.2 2.5e-42 144.5 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CEP09578.1 - 1.7e-08 34.8 0.0 4.8e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEP09578.1 - 0.0025 17.6 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_N PF08240.7 CEP09579.1 - 2.8e-19 68.8 0.1 4.7e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP09579.1 - 1.1e-16 60.5 0.0 1.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEP09579.1 - 0.029 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrwB_AAD_bind PF10412.4 CEP09579.1 - 0.1 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 CEP09579.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mannosyl_trans3 PF11051.3 CEP09580.1 - 2.1e-48 165.0 0.0 3.4e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 CEP09580.1 - 0.06 13.1 0.1 0.099 12.3 0.1 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_15 PF01793.11 CEP09581.1 - 6.9e-72 242.1 15.0 9.1e-72 241.7 10.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF1841 PF08897.6 CEP09581.1 - 0.08 12.7 0.1 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) Laminin_I PF06008.9 CEP09581.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Laminin Domain I Imm36 PF15597.1 CEP09581.1 - 4 7.6 7.7 1.2 9.2 0.5 3.0 2 2 1 3 3 3 0 Immunity protein 36 Na_Ca_ex PF01699.19 CEP09582.1 - 6.5e-44 148.9 37.5 3.3e-24 85.0 11.2 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.1 CEP09582.1 - 0.66 9.8 5.6 1.5 8.6 0.1 3.1 3 0 0 3 3 3 0 YWFCY protein NMO PF03060.10 CEP09583.1 - 1.6e-65 221.4 0.1 1.8e-65 221.2 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 CEP09583.1 - 0.0013 17.6 0.2 0.063 12.1 0.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.20 CEP09583.1 - 0.0016 17.4 0.0 0.32 9.8 0.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 CEP09583.1 - 0.0073 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.16 CEP09583.1 - 0.019 13.9 0.0 0.039 12.9 0.0 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF3947 PF13135.1 CEP09583.1 - 0.34 11.1 2.3 0.75 10.0 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) KfrA_N PF11740.3 CEP09585.1 - 0.63 10.4 10.4 2.9 8.3 0.8 3.6 3 1 1 4 4 4 0 Plasmid replication region DNA-binding N-term Prominin PF05478.6 CEP09585.1 - 0.68 7.3 2.3 0.81 7.1 0.1 1.8 1 1 0 1 1 1 0 Prominin DUF883 PF05957.8 CEP09585.1 - 2.4 8.6 19.2 26 5.3 1.0 4.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) tRNA-synt_2 PF00152.15 CEP09586.1 - 3e-120 400.9 0.1 3.8e-120 400.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CEP09586.1 - 2.1e-06 27.5 0.0 7.1e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CEP09586.1 - 9.9e-06 24.9 0.9 4.9e-05 22.6 0.1 2.6 4 0 0 4 4 4 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CEP09586.1 - 0.00018 21.1 0.3 0.06 12.9 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) GAD PF02938.9 CEP09586.1 - 0.0039 17.3 0.0 0.022 14.9 0.0 2.2 2 1 0 2 2 2 1 GAD domain Apolipoprotein PF01442.13 CEP09587.1 - 1.8e-05 24.3 5.6 3.3e-05 23.5 3.6 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 CEP09587.1 - 0.00039 20.2 14.4 0.04 13.7 5.3 2.3 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) Prominin PF05478.6 CEP09587.1 - 0.0079 13.7 3.1 0.0095 13.5 1.6 1.4 1 1 0 1 1 1 1 Prominin WXG100 PF06013.7 CEP09587.1 - 0.018 15.0 12.1 0.036 14.0 2.9 2.6 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF883 PF05957.8 CEP09587.1 - 0.027 14.8 16.7 0.43 10.9 4.6 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.3 CEP09587.1 - 0.039 14.3 11.7 1.1 9.7 2.6 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Cupin_8 PF13621.1 CEP09587.1 - 0.15 11.5 4.2 0.19 11.2 2.9 1.3 1 0 0 1 1 1 0 Cupin-like domain ApoLp-III PF07464.6 CEP09587.1 - 0.63 10.0 12.8 0.21 11.5 0.9 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Syntaxin-6_N PF09177.6 CEP09587.1 - 0.7 10.3 10.5 4.8 7.6 5.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal YtxH PF12732.2 CEP09587.1 - 0.88 9.9 20.3 1.5e+04 -4.7 14.1 3.0 1 1 0 1 1 0 0 YtxH-like protein Hex_IIIa PF02455.11 CEP09587.1 - 0.91 8.1 11.6 1.2 7.7 8.1 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) YlqD PF11068.3 CEP09587.1 - 1.1 9.3 7.3 0.39 10.7 0.9 2.2 1 1 1 2 2 2 0 YlqD protein DinB PF05163.7 CEP09587.1 - 2.3 7.8 5.4 1.8 8.2 2.7 1.5 1 1 1 2 2 2 0 DinB family Remorin_C PF03763.8 CEP09587.1 - 2.5 7.6 19.6 1.5 8.3 3.1 2.5 1 1 0 2 2 2 0 Remorin, C-terminal region DUF3435 PF11917.3 CEP09587.1 - 2.8 6.5 8.8 5.5 5.6 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3435) DivIVA PF05103.8 CEP09587.1 - 3.1 7.8 14.8 2.9 7.9 4.7 2.3 1 1 1 2 2 2 0 DivIVA protein Exonuc_VII_L PF02601.10 CEP09587.1 - 4.9 6.2 10.9 13 4.8 7.6 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 CEP09587.1 - 6.3 6.7 12.5 14 5.5 8.7 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CPSase_sm_chain PF00988.17 CEP09588.1 - 4.7e-48 161.9 0.0 6.9e-48 161.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CEP09588.1 - 2.2e-41 141.4 0.0 3.1e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CEP09588.1 - 3.3e-06 26.6 0.3 0.005 16.3 0.2 3.1 1 1 0 1 1 1 1 Peptidase C26 Dynactin PF12455.3 CEP09589.1 - 1.4e-67 227.5 9.2 1.4e-67 227.5 6.4 5.2 6 1 0 7 7 7 1 Dynein associated protein CAP_GLY PF01302.20 CEP09589.1 - 2.6e-23 81.5 2.1 4.3e-23 80.7 1.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain Hydrolase_6 PF13344.1 CEP09591.1 - 3.8e-21 74.8 0.0 6.8e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP09591.1 - 1.4e-07 31.1 0.0 2.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CEP09591.1 - 1.2e-06 29.0 0.1 3.6e-06 27.5 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP09591.1 - 1.4e-05 25.3 0.0 0.22 11.7 0.0 2.8 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF4032 PF13224.1 CEP09591.1 - 0.017 14.8 0.0 0.048 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4032) Hydrolase_3 PF08282.7 CEP09591.1 - 0.019 14.5 0.1 0.062 12.8 0.0 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.16 CEP09592.1 - 1.2e-48 165.2 0.8 1.3e-48 165.1 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bacillus_HBL PF05791.6 CEP09593.1 - 0.056 12.8 0.8 0.1 11.9 0.6 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ELFV_dehydrog PF00208.16 CEP09594.1 - 7.7e-56 189.3 3.2 7.7e-54 182.8 0.2 2.3 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CEP09594.1 - 1.5e-47 160.4 0.0 2.5e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AlaDh_PNT_C PF01262.16 CEP09594.1 - 0.0028 17.2 0.1 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 CEP09594.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_GDH PF05088.7 CEP09594.1 - 0.032 11.6 0.1 0.16 9.3 0.0 2.0 2 1 1 3 3 3 0 Bacterial NAD-glutamate dehydrogenase NAD_binding_7 PF13241.1 CEP09594.1 - 0.085 13.1 0.2 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 CEP09594.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_M41 PF01434.13 CEP09595.1 - 5.7e-73 244.9 0.1 8e-73 244.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CEP09595.1 - 1.9e-43 147.8 0.0 5.1e-43 146.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CEP09595.1 - 3.2e-08 33.7 0.1 1.1e-07 32.0 0.1 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CEP09595.1 - 6.1e-05 23.8 0.0 0.0029 18.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CEP09595.1 - 0.00016 21.3 0.1 0.016 14.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CEP09595.1 - 0.00036 20.6 0.0 0.16 12.1 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CEP09595.1 - 0.0044 16.7 0.6 0.014 15.1 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 CEP09595.1 - 0.0048 15.6 0.0 0.0074 15.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CEP09595.1 - 0.0062 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CEP09595.1 - 0.0072 15.7 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CEP09595.1 - 0.013 15.8 0.1 0.6 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CEP09595.1 - 0.05 12.6 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 CEP09595.1 - 0.062 12.4 0.7 0.39 9.8 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 CEP09595.1 - 0.066 13.1 0.0 0.25 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CEP09595.1 - 0.078 12.8 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CEP09595.1 - 0.087 12.2 0.7 0.25 10.6 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEP09595.1 - 0.11 12.4 3.5 0.25 11.3 0.1 3.0 3 1 1 4 4 4 0 AAA ATPase domain DBD_Tnp_Mut PF03108.10 CEP09596.1 - 1.2e-05 24.7 0.7 5.3e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 MuDR family transposase FAR1 PF03101.10 CEP09596.1 - 0.0002 21.8 2.7 0.0002 21.8 1.8 2.3 2 1 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 CEP09596.1 - 0.0016 18.5 2.1 0.0016 18.5 1.4 2.3 2 1 0 2 2 2 1 Transcription factor AFT WD40 PF00400.27 CEP09597.1 - 1.8e-58 192.4 21.1 1.1e-12 47.2 0.0 6.8 6 1 1 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CEP09597.1 - 6.1e-37 126.8 4.7 1.5e-36 125.6 3.3 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 CEP09597.1 - 0.0015 18.2 0.1 0.049 13.3 0.0 2.9 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CEP09597.1 - 0.0025 16.0 0.7 0.37 8.8 0.1 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Abhydrolase_6 PF12697.2 CEP09598.1 - 9e-38 130.4 0.0 1.1e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP09598.1 - 4.1e-24 85.4 0.0 6.4e-23 81.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP09598.1 - 7.8e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CEP09598.1 - 0.0005 19.8 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 CEP09598.1 - 0.0009 19.1 0.0 0.0029 17.5 0.0 1.8 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Peptidase_S9 PF00326.16 CEP09598.1 - 0.0043 16.3 0.0 1.8 7.7 0.0 2.9 2 1 1 3 3 3 1 Prolyl oligopeptidase family Ndr PF03096.9 CEP09598.1 - 0.021 13.3 0.0 0.038 12.4 0.0 1.4 1 0 0 1 1 1 0 Ndr family Abhydrolase_4 PF08386.5 CEP09598.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 CEP09598.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UCH PF00443.24 CEP09599.1 - 2.7e-14 52.9 0.0 1.3e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Polysacc_deac_1 PF01522.16 CEP09599.1 - 5.1e-09 35.8 0.1 4e-08 32.9 0.0 2.5 3 0 0 3 3 3 1 Polysaccharide deacetylase UBA PF00627.26 CEP09599.1 - 3.1e-07 30.0 0.3 1e-06 28.3 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain DUF1664 PF07889.7 CEP09599.1 - 0.067 12.9 1.5 0.24 11.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ALO PF04030.9 CEP09600.1 - 2.1e-94 315.9 5.0 2.1e-94 315.9 3.4 1.5 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CEP09600.1 - 2e-29 101.8 0.0 2.9e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PDT PF00800.13 CEP09601.1 - 4.5e-31 107.7 0.3 6.8e-22 77.8 0.1 2.2 2 0 0 2 2 2 2 Prephenate dehydratase CM_2 PF01817.16 CEP09601.1 - 8.7e-20 70.5 1.2 2.2e-19 69.2 0.8 1.7 1 1 0 1 1 1 1 Chorismate mutase type II ACT PF01842.20 CEP09601.1 - 5.1e-07 29.0 0.0 1.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain Sec3_C PF09763.4 CEP09602.1 - 5e-155 517.4 12.2 5e-155 517.4 8.4 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CEP09602.1 - 1.5e-20 72.8 0.6 4.5e-20 71.2 0.4 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Adap_comp_sub PF00928.16 CEP09603.1 - 1.3e-30 106.3 0.0 2.3e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CEP09603.1 - 3.6e-06 26.7 0.2 5.6e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4337 PF14235.1 CEP09603.1 - 0.55 10.0 3.7 0.96 9.2 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CDC37_N PF03234.9 CEP09603.1 - 0.68 10.2 7.8 0.33 11.2 0.3 2.4 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding LIM PF00412.17 CEP09604.1 - 1.4e-30 105.1 60.9 1e-10 41.5 8.0 5.0 5 0 0 5 5 5 4 LIM domain Lsm_interact PF05391.6 CEP09604.1 - 0.019 14.3 0.1 0.019 14.3 0.1 2.3 2 0 0 2 2 2 0 Lsm interaction motif EPL1 PF10513.4 CEP09604.1 - 0.028 14.6 0.8 0.051 13.8 0.6 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like NTP_transferase PF00483.18 CEP09605.1 - 1.6e-26 93.1 0.0 2.2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CEP09605.1 - 1.1e-09 37.2 5.7 5.5e-06 25.6 0.1 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CEP09605.1 - 3.9e-08 33.5 0.0 6.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain zf-CCHC PF00098.18 CEP09607.1 - 0.00017 21.3 9.6 0.025 14.4 1.2 2.4 2 0 0 2 2 2 2 Zinc knuckle DDE_3 PF13358.1 CEP09609.1 - 8.6e-13 48.2 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease KCl_Cotrans_1 PF03522.10 CEP09610.1 - 0.016 14.7 1.6 0.016 14.7 1.1 2.9 3 0 0 3 3 3 0 K-Cl Co-transporter type 1 (KCC1) Pox_polyA_pol_N PF12630.2 CEP09610.1 - 0.042 13.9 0.2 0.053 13.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Rho_GDI PF02115.12 CEP09610.1 - 0.045 13.1 0.1 0.058 12.7 0.1 1.2 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Orbi_VP5 PF00901.12 CEP09610.1 - 0.055 11.6 0.3 0.065 11.4 0.2 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Nitroreductase PF00881.19 CEP09613.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Nitroreductase family Helitron_like_N PF14214.1 CEP09614.1 - 8.5e-23 81.0 0.2 2.2e-22 79.6 0.2 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 CEP09614.1 - 3.2e-06 26.3 0.1 5.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP09614.1 - 2.1e-05 24.2 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CEP09614.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.1 CEP09614.1 - 0.018 15.8 0.0 0.06 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CEP09614.1 - 0.039 13.9 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 CEP09614.1 - 0.04 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 CEP09614.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF4116 PF13475.1 CEP09616.1 - 0.014 14.8 0.7 0.23 11.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Sigma_reg_N PF13800.1 CEP09616.1 - 3.8 7.6 5.3 1e+02 3.0 3.7 2.1 1 1 0 1 1 1 0 Sigma factor regulator N-terminal GTP_EFTU PF00009.22 CEP09619.1 - 7e-58 195.1 0.0 9.2e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CEP09619.1 - 8.5e-17 61.0 0.8 8.5e-17 61.0 0.6 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 CEP09619.1 - 1.2e-15 57.4 0.0 3.1e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.1 CEP09619.1 - 0.00051 19.6 0.1 0.0012 18.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CEP09619.1 - 0.0006 19.7 0.6 0.0018 18.2 0.4 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_A17 PF05380.8 CEP09620.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase HTH_Tnp_Tc3_2 PF01498.13 CEP09622.1 - 3.7e-10 39.7 0.2 1.8e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 CEP09622.1 - 3.9e-08 33.4 0.1 1.1e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CEP09622.1 - 3.9e-06 26.7 0.0 9.2e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP09622.1 - 2.9e-05 24.7 0.2 0.00062 20.5 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 CEP09622.1 - 0.00039 19.9 0.0 0.0022 17.5 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.10 CEP09622.1 - 0.041 13.7 0.3 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.17 CEP09622.1 - 0.058 13.2 0.0 1 9.2 0.0 2.8 4 0 0 4 4 4 0 Helix-turn-helix Fe_dep_repress PF01325.14 CEP09622.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.14 CEP09622.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DDE_3 PF13358.1 CEP09623.1 - 5e-21 74.9 0.1 8.4e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP09623.1 - 0.00068 19.7 0.0 0.0024 17.9 0.0 1.9 2 1 0 2 2 2 1 Integrase core domain Alpha-amylase PF00128.19 CEP09623.1 - 0.028 13.8 0.2 1.6 8.0 0.0 2.1 1 1 1 2 2 2 0 Alpha amylase, catalytic domain DDE_1 PF03184.14 CEP09623.1 - 0.075 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease PIF1 PF05970.9 CEP09624.1 - 1.2e-07 31.0 0.0 2.3e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase L31 PF09784.4 CEP09627.1 - 2.4e-38 130.3 0.1 2.7e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Nop52 PF05997.7 CEP09628.1 - 5.6e-59 199.1 0.8 8e-59 198.6 0.5 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF2457 PF10446.4 CEP09628.1 - 1.4 7.5 21.3 1.9 7.1 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 CEP09628.1 - 7.5 4.3 20.9 10 3.8 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family RabGAP-TBC PF00566.13 CEP09629.1 - 2.2e-47 161.3 3.5 4.7e-47 160.2 2.5 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_L32e PF01655.13 CEP09630.1 - 2.1e-47 159.7 1.0 2.5e-47 159.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DSPc PF00782.15 CEP09631.1 - 4.5e-08 32.7 0.2 3.7e-07 29.7 0.0 2.4 1 1 2 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP09631.1 - 5.9e-08 32.3 0.0 8.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CEP09631.1 - 2.5e-06 27.8 0.0 4.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Rhodanese PF00581.15 CEP09631.1 - 2.2e-05 24.7 0.0 5.8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain PTPlike_phytase PF14566.1 CEP09631.1 - 0.0002 21.4 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 CEP09631.1 - 0.0062 16.0 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 CEP09631.1 - 0.009 15.3 0.7 0.029 13.7 0.1 2.1 2 1 0 2 2 2 1 Tyrosine phosphatase family GTP_EFTU PF00009.22 CEP09631.1 - 0.013 14.9 0.3 0.018 14.4 0.2 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Dict-STAT-coil PF09267.5 CEP09631.1 - 0.023 14.8 0.3 0.046 13.9 0.2 1.4 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DUF4116 PF13475.1 CEP09631.1 - 0.034 13.6 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) F-box-like PF12937.2 CEP09632.1 - 0.00096 18.8 2.1 0.002 17.7 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP09632.1 - 0.0097 15.5 1.6 0.02 14.5 1.1 1.5 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 CEP09634.1 - 0.0055 16.2 14.7 0.034 13.7 0.5 5.7 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP09634.1 - 1.8 8.3 7.8 4.2 7.1 0.2 4.3 4 0 0 4 4 4 0 Leucine rich repeat SNF5 PF04855.7 CEP09635.1 - 2.2e-54 184.5 2.4 3.6e-27 95.4 1.1 2.3 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.1 CEP09636.1 - 9.2e-17 61.1 0.0 6.4e-07 29.5 0.0 4.8 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.17 CEP09636.1 - 1.1e-14 53.0 1.1 0.024 14.6 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat Cnd3 PF12719.2 CEP09636.1 - 3.2e-06 26.3 2.0 0.0085 15.1 0.0 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 CEP09636.1 - 2.2e-05 24.2 1.1 0.00025 20.9 0.1 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 CEP09636.1 - 8.3e-05 22.9 2.3 1.7 9.2 0.0 5.6 6 0 0 6 6 6 1 HEAT-like repeat API5 PF05918.6 CEP09636.1 - 0.0066 15.0 2.3 0.025 13.0 0.3 2.3 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) Cnd1 PF12717.2 CEP09636.1 - 0.031 14.1 0.2 0.031 14.1 0.2 4.6 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.3 CEP09636.1 - 0.19 11.6 2.0 0.78 9.6 0.1 2.9 3 0 0 3 3 3 0 V-ATPase subunit H SRF-TF PF00319.13 CEP09638.1 - 8.5e-22 76.1 0.0 1.4e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PAT1 PF09770.4 CEP09638.1 - 0.62 8.2 56.5 0.8 7.8 39.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CEP09638.1 - 4.3 5.3 61.6 5.6 5.0 42.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0029 PF01205.14 CEP09639.1 - 1.7e-30 104.9 0.1 3.3e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CEP09639.1 - 1.7e-15 56.9 0.4 3.5e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 RWD domain DUF2342 PF10103.4 CEP09639.1 - 0.0027 16.7 0.2 0.0054 15.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2342) Tcp11 PF05794.8 CEP09640.1 - 5.7e-34 117.5 5.0 9.5e-34 116.8 3.5 1.4 1 0 0 1 1 1 1 T-complex protein 11 DC_STAMP PF07782.8 CEP09641.1 - 0.04 13.5 3.1 0.27 10.8 0.6 2.7 2 1 0 2 2 2 0 DC-STAMP-like protein UPF0118 PF01594.11 CEP09641.1 - 0.93 8.4 10.3 0.3 10.0 3.2 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF20 SET PF00856.23 CEP09642.1 - 2.7e-09 37.5 0.2 4.6e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 CEP09642.1 - 1.3e-05 24.9 12.5 1.3e-05 24.9 8.7 2.3 2 0 0 2 2 2 1 MYND finger Mid2 PF04478.7 CEP09643.1 - 0.0041 16.5 0.7 0.017 14.5 0.1 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 CEP09643.1 - 0.006 16.0 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 CEP09643.1 - 0.024 14.3 0.3 0.069 12.8 0.2 1.7 1 0 0 1 1 1 0 TMEM154 protein family CcoS PF03597.10 CEP09643.1 - 2.9 7.4 4.9 5.4 6.5 3.4 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF3425 PF11905.3 CEP09644.1 - 7e-13 48.6 5.9 1.6e-10 40.9 4.1 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CEP09644.1 - 6.9e-08 32.3 5.7 6.9e-08 32.3 4.0 2.8 3 0 0 3 3 3 1 bZIP transcription factor Helicase_Sgs1 PF11408.3 CEP09644.1 - 0.0085 15.9 2.7 1.5 8.7 0.0 3.3 3 0 0 3 3 3 1 Sgs1 RecQ helicase VDE PF07137.6 CEP09644.1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) Phlebovirus_NSM PF07246.6 CEP09644.1 - 0.63 9.1 5.8 0.48 9.5 0.2 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Glutaredoxin2_C PF04399.8 CEP09644.1 - 2.1 7.9 8.2 0.067 12.7 0.6 2.3 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Dynamin_N PF00350.18 CEP09644.1 - 5.4 6.8 9.9 1.6 8.4 0.0 2.9 4 0 0 4 4 4 0 Dynamin family DUF3425 PF11905.3 CEP09645.1 - 1.8e-08 34.3 5.8 2e-07 30.9 1.2 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.10 CEP09645.1 - 0.002 17.9 16.3 0.083 12.7 1.0 2.6 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 CEP09645.1 - 0.017 15.0 18.6 0.13 12.2 12.8 2.3 1 1 1 2 2 2 0 bZIP transcription factor Shugoshin_N PF07558.6 CEP09645.1 - 0.037 13.7 0.4 0.075 12.7 0.3 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Fungal_trans PF04082.13 CEP09646.1 - 6.7e-22 77.6 1.0 8.9e-22 77.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP09646.1 - 8.2e-11 41.6 11.9 8.2e-11 41.6 8.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrD_C_2 PF13538.1 CEP09650.1 - 3.9e-11 43.0 0.0 6.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEP09650.1 - 4.4e-06 24.7 0.0 5.3e-06 24.4 0.0 1.1 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 CEP09650.1 - 4.6e-05 23.0 0.0 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase GDH_N PF12466.3 CEP09650.1 - 0.0073 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutamate dehydrogenase N terminal zf-CCHC PF00098.18 CEP09651.1 - 2.7e-07 30.1 2.2 5e-07 29.3 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEP09651.1 - 0.001 19.0 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 CEP09651.1 - 0.041 13.5 1.2 0.091 12.4 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 CEP09651.1 - 0.063 13.0 1.6 0.11 12.2 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Serglycin PF04360.7 CEP09651.1 - 2.2 8.0 5.7 5.1 6.8 4.0 1.7 1 1 0 1 1 1 0 Serglycin DUF3246 PF11596.3 CEP09651.1 - 4.5 6.4 9.4 15 4.7 6.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) zf-CCHC PF00098.18 CEP09652.1 - 4.1e-06 26.4 9.5 0.00049 19.9 0.7 2.9 3 0 0 3 3 3 2 Zinc knuckle Adeno_E4_34 PF04528.8 CEP09652.1 - 0.0016 18.0 0.2 0.0021 17.6 0.1 1.2 1 0 0 1 1 1 1 Adenovirus early E4 34 kDa protein conserved region HNH PF01844.18 CEP09652.1 - 0.0021 17.9 0.5 0.0021 17.9 0.4 1.9 2 0 0 2 2 2 1 HNH endonuclease Zn_Tnp_IS1595 PF12760.2 CEP09652.1 - 0.0097 15.6 2.6 0.0097 15.6 1.8 1.7 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-CCHC_4 PF14392.1 CEP09652.1 - 0.033 13.8 5.1 0.89 9.2 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle zinc-ribbons_6 PF07191.7 CEP09652.1 - 0.042 13.6 5.8 0.27 11.0 0.2 2.3 1 1 1 2 2 2 0 zinc-ribbons RRM_6 PF14259.1 CEP09652.1 - 0.05 13.5 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cytochrome_C7 PF14522.1 CEP09652.1 - 0.18 11.4 4.6 0.31 10.7 3.2 1.4 1 0 0 1 1 1 0 Cytochrome c7 TNFR_c6 PF00020.13 CEP09652.1 - 0.26 11.3 4.2 4.3 7.4 0.3 2.5 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region zf-C4pol PF14260.1 CEP09652.1 - 1 9.3 6.4 0.92 9.5 0.5 2.2 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF721 PF05258.7 CEP09653.1 - 0.04 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF721) zf-CCHC PF00098.18 CEP09654.1 - 0.0012 18.7 1.7 0.0012 18.7 1.2 1.8 2 0 0 2 2 2 1 Zinc knuckle ADAM_CR PF08516.7 CEP09654.1 - 0.0034 17.4 0.3 0.0047 16.9 0.2 1.2 1 0 0 1 1 1 1 ADAM cysteine-rich zf-CCHC_3 PF13917.1 CEP09654.1 - 0.0034 17.0 3.4 0.0034 17.0 2.4 1.8 1 1 1 2 2 2 1 Zinc knuckle FBP PF07299.6 CEP09654.1 - 0.08 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) zf-CCHC_4 PF14392.1 CEP09655.1 - 0.0014 18.2 7.7 0.15 11.7 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 CEP09655.1 - 0.0037 17.1 6.7 0.052 13.4 0.7 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-BED PF02892.10 CEP09655.1 - 0.016 14.9 4.2 0.56 10.0 0.8 2.3 2 0 0 2 2 2 0 BED zinc finger zf-ribbon_3 PF13248.1 CEP09655.1 - 0.028 13.6 0.6 4.7 6.5 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CEP09655.1 - 0.055 13.2 6.0 1.9 8.3 0.3 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 CEP09655.1 - 0.092 12.2 1.0 5.8 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Baculo_ME53 PF06061.6 CEP09655.1 - 0.092 11.7 0.4 0.11 11.4 0.3 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 DZR PF12773.2 CEP09655.1 - 0.45 10.3 4.5 4.6 7.1 3.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.14 CEP09655.1 - 1.1 8.9 5.8 8.1 6.1 4.0 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-CCHC_6 PF15288.1 CEP09655.1 - 4.5 7.0 10.4 1.3 8.7 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle Ogr_Delta PF04606.7 CEP09655.1 - 6.9 6.4 8.6 3.6 7.3 0.9 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Trp_oprn_chp PF09534.5 CEP09656.1 - 0.082 12.5 0.2 0.098 12.2 0.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3290 PF11694.3 CEP09656.1 - 0.36 10.5 2.8 0.47 10.1 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Cytochrom_B_C PF00032.12 CEP09656.1 - 0.47 10.7 4.9 1.4 9.1 2.7 2.0 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF485 PF04341.7 CEP09656.1 - 0.8 9.4 5.1 1.4 8.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Sec62 PF03839.11 CEP09656.1 - 2.7 7.3 5.4 0.96 8.8 2.2 1.4 1 1 0 1 1 1 0 Translocation protein Sec62 Hid1 PF12722.2 CEP09657.1 - 9.6e-179 596.0 10.8 4.2e-178 593.9 7.5 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CEP09657.1 - 5.6e-74 249.4 4.7 7.7e-74 249.0 3.3 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Homeobox PF00046.24 CEP09658.1 - 2.6e-15 55.7 6.1 2.6e-15 55.7 4.2 1.7 2 0 0 2 2 2 1 Homeobox domain DUF658 PF04936.7 CEP09658.1 - 0.00085 19.2 0.2 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF658) Arrestin_C PF02752.17 CEP09658.1 - 0.026 14.6 1.1 0.034 14.2 0.7 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain MSA_2 PF00985.12 CEP09658.1 - 0.19 11.8 7.6 0.26 11.4 5.3 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Neur_chan_memb PF02932.11 CEP09658.1 - 0.39 10.5 4.3 0.44 10.3 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNase_H2-Ydr279 PF09468.5 CEP09658.1 - 0.55 9.3 8.9 0.58 9.3 5.7 1.3 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PMSI1 PF15322.1 CEP09658.1 - 1.8 7.6 6.3 2.3 7.2 4.3 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative zf-C2H2 PF00096.21 CEP09660.1 - 8.6e-07 28.9 12.6 0.0013 18.9 0.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP09660.1 - 2e-06 27.8 12.9 0.00023 21.2 2.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP09660.1 - 0.0011 19.1 18.7 0.019 15.2 1.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CEP09660.1 - 0.0065 16.6 4.2 1.5 9.1 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CEP09660.1 - 0.19 11.4 12.9 0.35 10.5 2.2 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Phosphodiest PF01663.17 CEP09661.1 - 1.5e-10 41.0 4.3 6.2e-10 38.9 1.1 2.5 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CEP09661.1 - 0.013 14.9 0.8 0.039 13.3 0.5 1.7 1 1 0 1 1 1 0 Metalloenzyme superfamily DUF2231 PF09990.4 CEP09661.1 - 0.019 15.2 1.9 0.019 15.2 1.3 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Na_Ca_ex PF01699.19 CEP09661.1 - 0.15 11.6 6.1 0.058 13.0 0.4 2.5 2 0 0 2 2 2 0 Sodium/calcium exchanger protein Ribosomal_L1 PF00687.16 CEP09662.1 - 1.5e-37 129.0 8.4 1.5e-37 129.0 5.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family PAP2_C PF14360.1 CEP09663.1 - 2.5e-16 59.6 9.9 2.5e-16 59.6 6.9 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 CEP09663.1 - 1.3e-05 24.8 6.7 1.3e-05 24.8 4.7 2.1 2 1 0 2 2 2 1 PAP2 superfamily PhyH PF05721.8 CEP09665.1 - 1.6e-48 165.5 0.0 1.9e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fork_head PF00250.13 CEP09666.1 - 1.7e-35 120.9 0.3 4.1e-35 119.7 0.2 1.7 1 0 0 1 1 1 1 Fork head domain Sugar_tr PF00083.19 CEP09667.1 - 4.1e-16 58.5 14.4 4.8e-16 58.3 10.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP09667.1 - 0.0035 16.1 11.5 0.01 14.6 8.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3021 PF11457.3 CEP09667.1 - 2.5 7.9 12.3 0.23 11.3 4.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) DUF1418 PF07214.7 CEP09667.1 - 6 6.5 7.4 7.5 6.2 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) SRC-1 PF08832.5 CEP09669.1 - 0.23 12.2 0.3 0.23 12.2 0.2 2.3 2 0 0 2 2 2 0 Steroid receptor coactivator DAO PF01266.19 CEP09670.1 - 1.3e-49 169.0 0.0 2e-49 168.4 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP09670.1 - 4e-08 33.1 0.0 8.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP09670.1 - 1.3e-05 25.1 0.0 0.019 14.8 0.0 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP09670.1 - 0.0025 17.5 0.0 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 CEP09670.1 - 0.0027 16.6 0.0 0.24 10.2 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 CEP09670.1 - 0.0066 14.9 0.0 0.64 8.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 CEP09670.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 CEP09670.1 - 0.08 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CEP09670.1 - 0.11 11.3 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FGGY_C PF02782.11 CEP09671.1 - 2.6e-69 232.8 0.5 4.5e-69 232.0 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CEP09671.1 - 4.2e-68 229.3 0.1 8.3e-68 228.3 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 CEP09671.1 - 3e-55 187.3 10.4 7.5e-42 143.3 4.8 2.2 2 0 0 2 2 2 2 Cation efflux family BcrAD_BadFG PF01869.15 CEP09671.1 - 0.012 14.8 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF4010 PF13194.1 CEP09671.1 - 0.019 14.3 7.2 0.11 11.7 2.6 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4010) TMEM141 PF15110.1 CEP09671.1 - 0.098 12.9 0.9 1.8 8.8 0.1 2.6 2 0 0 2 2 2 0 TMEM141 protein family GtrA PF04138.9 CEP09671.1 - 4 7.4 9.4 13 5.8 3.4 2.5 1 1 1 2 2 2 0 GtrA-like protein DUF1295 PF06966.7 CEP09672.1 - 1.8e-42 145.2 5.1 2.6e-42 144.7 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) HEAT_2 PF13646.1 CEP09674.1 - 3e-19 69.0 16.5 1e-06 28.9 0.0 8.7 7 2 2 10 10 10 5 HEAT repeats HEAT PF02985.17 CEP09674.1 - 7.7e-19 66.0 10.2 0.0021 17.9 0.0 10.9 11 0 0 11 11 11 5 HEAT repeat Vac14_Fab1_bd PF12755.2 CEP09674.1 - 1.6e-17 63.6 3.8 5.1e-05 23.5 0.0 7.3 4 2 3 7 7 7 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CEP09674.1 - 1.3e-14 54.2 17.7 5.2e-05 23.5 0.0 12.2 12 2 3 15 15 14 3 HEAT-like repeat CLASP_N PF12348.3 CEP09674.1 - 6.6e-09 35.4 3.6 0.055 12.8 0.0 5.5 5 1 1 6 6 6 4 CLASP N terminal RIX1 PF08167.7 CEP09674.1 - 7.7e-06 25.6 1.9 0.096 12.3 0.0 5.7 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 CEP09674.1 - 1.1e-05 24.4 7.6 0.37 9.4 0.2 6.3 5 2 2 8 8 8 3 RNAPII transcription regulator C-terminal DUF3385 PF11865.3 CEP09674.1 - 0.001 18.9 2.7 20 5.0 0.0 6.5 6 2 1 7 7 7 0 Domain of unknown function (DUF3385) Arm PF00514.18 CEP09674.1 - 0.0096 15.7 9.7 5.3 7.0 0.0 7.0 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat Dopey_N PF04118.9 CEP09674.1 - 0.015 14.0 1.4 0.17 10.5 0.0 2.7 2 0 0 2 2 2 0 Dopey, N-terminal DUF2435 PF10363.4 CEP09674.1 - 0.041 13.7 0.6 0.74 9.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) CorA PF01544.13 CEP09675.1 - 0.032 13.2 10.2 0.059 12.4 7.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein XhlA PF10779.4 CEP09675.1 - 0.099 12.5 0.2 0.099 12.5 0.2 3.4 3 1 1 4 4 4 0 Haemolysin XhlA Atg14 PF10186.4 CEP09675.1 - 0.23 10.3 19.5 0.045 12.6 9.4 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 CEP09675.1 - 0.73 10.0 11.8 0.22 11.6 4.7 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DIL PF01843.14 CEP09675.1 - 1.9 8.4 7.0 0.36 10.7 0.1 2.6 2 1 0 2 2 2 0 DIL domain DUF4407 PF14362.1 CEP09675.1 - 8.6 5.2 11.1 3.8 6.3 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) WD40 PF00400.27 CEP09676.1 - 2.7e-20 71.3 4.2 0.021 14.6 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CEP09676.1 - 0.005 15.1 0.4 0.14 10.4 0.1 2.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain YL1 PF05764.8 CEP09676.1 - 0.031 13.8 16.3 0.045 13.3 11.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Merozoite_SPAM PF07133.6 CEP09676.1 - 0.044 13.6 14.2 0.095 12.5 9.8 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RR_TM4-6 PF06459.7 CEP09676.1 - 0.14 12.0 7.6 0.19 11.5 5.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 CEP09676.1 - 0.18 9.7 16.2 0.24 9.3 11.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CEP09676.1 - 2.7 5.9 12.2 3.7 5.4 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SPT6_acidic PF14632.1 CEP09676.1 - 3.3 7.9 18.4 8.1 6.6 12.7 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 RhoGAP PF00620.22 CEP09677.1 - 1.8e-50 170.4 0.1 4.9e-50 169.0 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 CEP09677.1 - 8.9e-08 31.7 3.6 8.9e-08 31.7 2.5 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.17 CEP09677.1 - 2.2e-06 27.6 7.5 2.2e-06 27.6 5.2 2.5 2 0 0 2 2 2 1 LIM domain Tup_N PF08581.5 CEP09677.1 - 0.24 11.5 8.2 2 8.6 0.8 3.0 2 1 0 2 2 2 0 Tup N-terminal ENTH PF01417.15 CEP09679.1 - 5.7e-46 155.4 0.1 1e-45 154.6 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CEP09679.1 - 5.8e-05 21.9 0.0 9.3e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 CEP09679.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 VHS domain Cpn60_TCP1 PF00118.19 CEP09680.1 - 2e-146 488.4 13.5 3.2e-146 487.7 9.4 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PH PF00169.24 CEP09680.1 - 6e-06 26.4 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 CEP09680.1 - 0.013 15.6 0.0 0.042 13.9 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PcfK PF14058.1 CEP09680.1 - 0.2 11.8 0.9 0.31 11.1 0.2 1.6 2 0 0 2 2 2 0 PcfK-like protein MCP_N PF05581.7 CEP09681.1 - 0.026 14.6 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus Phi_1 PF04674.7 CEP09681.1 - 0.049 12.8 0.0 0.052 12.7 0.0 1.0 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region WD40 PF00400.27 CEP09682.1 - 4e-17 61.3 4.0 1.7e-05 24.5 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Xylanase PF13201.1 CEP09682.1 - 0.0014 17.5 0.1 0.0022 16.8 0.1 1.2 1 0 0 1 1 1 1 Putative glycoside hydrolase xylanase Ribosomal_L22e PF01776.12 CEP09683.1 - 9.2e-50 167.3 1.9 1.1e-49 167.1 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Metallophos PF00149.23 CEP09684.1 - 7.5e-12 45.0 3.0 2.4e-11 43.4 1.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_6 PF13516.1 CEP09685.1 - 1.8e-14 52.1 12.7 0.00035 20.3 0.1 8.3 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 CEP09685.1 - 1e-12 47.3 12.2 6.9e-05 22.3 0.6 7.1 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP09685.1 - 9.6e-11 40.1 3.2 0.3 11.2 0.0 8.3 9 1 0 9 9 8 1 Leucine Rich Repeat LRR_8 PF13855.1 CEP09685.1 - 1.1e-08 34.7 12.9 0.0015 18.2 0.4 6.3 3 2 4 7 7 7 4 Leucine rich repeat LRR_7 PF13504.1 CEP09685.1 - 0.0079 16.2 12.6 18 6.1 0.0 6.4 6 0 0 6 6 6 0 Leucine rich repeat DUF2347 PF09804.4 CEP09685.1 - 0.061 12.6 0.9 0.087 12.0 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) FAM24 PF15193.1 CEP09685.1 - 0.15 12.3 0.3 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 FAM24 family SDA1 PF05285.7 CEP09685.1 - 0.28 10.4 16.2 0.39 9.9 11.2 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol3_a_NII PF11490.3 CEP09685.1 - 0.35 10.4 12.1 1.1 8.9 8.4 1.9 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Trypan_PARP PF05887.6 CEP09685.1 - 3.8 7.3 18.8 6.6 6.5 13.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ATP-synt_E PF05680.7 CEP09685.1 - 9.5 6.2 11.9 1.8e+02 2.1 0.0 2.7 2 0 0 2 2 2 0 ATP synthase E chain BSP_II PF05432.6 CEP09686.1 - 0.003 16.9 1.9 0.0035 16.6 1.3 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 CEP09686.1 - 0.025 14.8 2.8 0.044 14.0 1.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4422 PF14393.1 CEP09686.1 - 0.24 10.9 4.1 0.28 10.7 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4422) SR-25 PF10500.4 CEP09686.1 - 0.74 9.2 17.8 0.99 8.8 12.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.6 CEP09686.1 - 6.8 4.8 15.7 8.1 4.6 10.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Snf7 PF03357.16 CEP09687.1 - 5.9e-22 77.8 16.7 7.4e-22 77.5 11.6 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 CEP09687.1 - 0.00053 19.4 1.4 0.00078 18.8 1.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Coatomer_E PF04733.9 CEP09687.1 - 0.016 14.4 1.5 0.028 13.6 1.1 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit VTC PF09359.5 CEP09688.1 - 1.8e-24 86.2 0.4 2.7e-24 85.7 0.3 1.3 1 0 0 1 1 1 1 VTC domain ChaC PF04752.7 CEP09689.1 - 9.1e-67 224.4 0.0 1.1e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein AIG2 PF06094.7 CEP09689.1 - 0.027 14.9 0.1 0.042 14.3 0.1 1.3 1 0 0 1 1 1 0 AIG2-like family Zip PF02535.17 CEP09690.1 - 8e-47 159.7 12.7 9.5e-47 159.5 8.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 CEP09690.1 - 0.085 12.1 7.3 0.063 12.5 2.1 2.4 2 0 0 2 2 2 0 HupE / UreJ protein Cation_efflux PF01545.16 CEP09690.1 - 0.4 9.7 9.2 0.042 12.9 0.6 2.2 2 0 0 2 2 2 0 Cation efflux family 2OG-FeII_Oxy PF03171.15 CEP09691.1 - 0.00017 21.7 0.0 0.00051 20.2 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAP_central PF04928.12 CEP09692.1 - 2.5e-44 150.9 0.0 3.8e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CEP09692.1 - 1.5e-10 40.7 0.4 2.6e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CEP09692.1 - 7.1e-05 23.0 0.1 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain GPI-anchored PF10342.4 CEP09693.1 - 1.5e-15 57.4 0.2 1.5e-15 57.4 0.2 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Melittin PF01372.12 CEP09693.1 - 0.038 13.3 0.1 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Melittin DUF3446 PF11928.3 CEP09693.1 - 1 9.6 11.7 0.14 12.3 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) G-patch PF01585.18 CEP09694.1 - 2.2e-16 59.3 0.5 2.2e-16 59.3 0.4 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CEP09694.1 - 6.7e-09 35.4 5.2 7e-09 35.4 0.9 2.9 3 0 0 3 3 3 1 DExH-box splicing factor binding site DUF4661 PF15576.1 CEP09694.1 - 0.094 12.3 3.7 0.16 11.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) Hpt PF01627.18 CEP09695.1 - 2.8e-14 52.8 0.5 5.1e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 Hpt domain UPF0257 PF06788.8 CEP09695.1 - 0.01 15.0 0.7 0.012 14.8 0.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0257) DUF1018 PF06252.7 CEP09695.1 - 0.22 12.0 4.2 1.3 9.5 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) DUF464 PF04327.7 CEP09695.1 - 0.76 10.0 4.5 0.19 12.0 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF464) DUF2422 PF10337.4 CEP09695.1 - 0.77 8.4 6.3 0.92 8.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) AAA_23 PF13476.1 CEP09695.1 - 1 9.6 17.2 1.5 9.1 11.9 1.2 1 0 0 1 1 1 0 AAA domain FKBP_N PF01346.13 CEP09695.1 - 2.4 8.2 14.8 0.28 11.2 6.2 2.1 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Muted PF14942.1 CEP09695.1 - 2.6 7.8 15.4 0.77 9.6 6.5 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF2203 PF09969.4 CEP09695.1 - 7.8 6.7 7.9 18 5.5 2.1 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SCAN PF02023.12 CEP09695.1 - 9.2 5.8 7.9 4.7 6.7 0.9 3.0 1 1 1 2 2 2 0 SCAN domain Aminotran_3 PF00202.16 CEP09696.1 - 4.8e-109 364.2 1.6 5.9e-109 363.9 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-III Use1 PF09753.4 CEP09696.1 - 1e-17 64.4 11.7 1e-17 64.4 8.1 2.2 2 0 0 2 2 2 1 Membrane fusion protein Use1 BLOC1_2 PF10046.4 CEP09696.1 - 3.7e-09 36.6 9.3 4.1e-07 30.0 3.1 5.0 4 1 1 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Aminotran_1_2 PF00155.16 CEP09696.1 - 0.004 16.1 0.0 0.004 16.1 0.0 2.1 3 0 0 3 3 3 1 Aminotransferase class I and II DUF2999 PF11212.3 CEP09696.1 - 0.046 13.7 0.8 0.44 10.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) RhoGEF PF00621.15 CEP09697.1 - 2.9e-26 92.4 1.9 4.7e-26 91.7 1.3 1.3 1 0 0 1 1 1 1 RhoGEF domain TPR_11 PF13414.1 CEP09698.1 - 9.4e-21 73.2 1.6 1e-10 41.0 0.0 3.2 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 CEP09698.1 - 2.7e-17 61.1 0.8 0.0071 16.1 0.0 5.4 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 CEP09698.1 - 3.5e-16 58.0 1.2 0.0016 17.9 0.1 5.3 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 CEP09698.1 - 6.9e-12 44.5 0.3 0.0009 19.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP09698.1 - 6.9e-12 44.2 0.2 0.015 15.0 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEP09698.1 - 3.1e-11 43.0 0.5 1.2e-06 28.3 0.2 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP09698.1 - 4e-11 43.1 0.2 1.2e-06 28.7 0.0 3.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP09698.1 - 1.2e-09 38.5 0.0 0.00048 20.7 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP09698.1 - 3.1e-08 33.5 0.2 0.023 15.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP09698.1 - 6.7e-07 29.4 0.0 0.34 11.6 0.0 4.5 1 1 4 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP09698.1 - 7.1e-07 29.2 2.2 0.00058 19.9 0.1 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CEP09698.1 - 9.7e-07 28.1 0.2 0.02 14.6 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 CEP09698.1 - 0.00037 20.5 0.2 0.064 13.3 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CEP09698.1 - 0.00065 18.8 0.0 0.00093 18.3 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP09698.1 - 0.056 13.4 0.2 4 7.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Paf67 PF10255.4 CEP09698.1 - 0.1 11.4 0.0 0.62 8.8 0.0 1.9 1 1 1 2 2 2 0 RNA polymerase I-associated factor PAF67 NSF PF02071.15 CEP09698.1 - 0.13 12.9 0.2 2.9 8.8 0.0 3.3 3 0 0 3 3 2 0 Aromatic-di-Alanine (AdAR) repeat Sec15 PF04091.7 CEP09699.1 - 1.5e-91 306.9 9.0 3.5e-91 305.7 6.3 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.6 CEP09699.1 - 0.00026 20.7 0.2 0.00026 20.7 0.1 3.8 4 1 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.6 CEP09699.1 - 0.00029 20.7 5.5 0.0016 18.3 2.7 2.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2203 PF09969.4 CEP09699.1 - 0.0099 16.0 4.8 0.24 11.6 0.2 3.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2203) COG5 PF10392.4 CEP09699.1 - 0.26 11.2 6.6 0.14 12.0 0.5 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DnaJ PF00226.26 CEP09700.1 - 5.5e-11 42.0 0.7 5.5e-11 42.0 0.5 1.9 2 0 0 2 2 2 1 DnaJ domain V_ATPase_I PF01496.14 CEP09700.1 - 2.1 6.0 4.9 2.4 5.8 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med26 PF08711.6 CEP09701.1 - 0.00025 20.5 0.5 0.00054 19.4 0.4 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.19 CEP09701.1 - 0.0026 17.4 2.4 0.0049 16.5 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.11 CEP09702.1 - 1.1e-37 129.6 61.5 1.3e-30 106.3 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP09702.1 - 5.9e-13 48.0 8.8 5.9e-13 48.0 6.1 2.4 1 1 0 2 2 2 2 MFS/sugar transport protein Peptidase_M56 PF05569.6 CEP09702.1 - 0.045 12.7 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 MRAP PF15183.1 CEP09702.1 - 0.67 9.6 3.4 0.25 10.9 0.1 2.0 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family RhoGEF PF00621.15 CEP09703.1 - 1.2e-42 145.8 3.2 2e-42 145.0 2.2 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 CEP09703.1 - 1.7e-26 92.6 0.4 5.2e-26 91.1 0.3 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 CEP09703.1 - 5.9e-17 61.5 2.6 2.3e-07 30.7 0.3 2.7 1 1 1 2 2 2 2 CDC24 Calponin PB1 PF00564.19 CEP09703.1 - 1e-14 53.9 1.1 1.9e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 PB1 domain PH PF00169.24 CEP09703.1 - 5.7e-05 23.2 0.3 0.00015 21.8 0.2 1.7 1 0 0 1 1 1 1 PH domain Sec5 PF15469.1 CEP09703.1 - 0.1 12.2 5.5 0.32 10.6 0.3 2.6 2 0 0 2 2 2 0 Exocyst complex component Sec5 OrfB_Zn_ribbon PF07282.6 CEP09706.1 - 0.00082 18.9 0.2 0.0021 17.6 0.1 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain UPF0081 PF03652.10 CEP09706.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) Glyco_hydro_3 PF00933.16 CEP09707.1 - 3e-72 243.1 0.2 4.1e-72 242.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CEP09707.1 - 3.6e-41 141.1 0.0 5.9e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CEP09707.1 - 2.5e-09 36.9 0.0 4.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain RNase_PH_C PF03725.10 CEP09707.1 - 0.0068 16.3 0.1 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 WHEP-TRS PF00458.15 CEP09707.1 - 0.031 13.9 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 WHEP-TRS domain CAF1 PF04857.15 CEP09708.1 - 6.3e-57 192.8 0.9 8.6e-57 192.4 0.6 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease HSCB_C PF07743.8 CEP09709.1 - 0.0054 17.1 2.1 0.015 15.7 1.4 1.9 1 1 0 1 1 1 1 HSCB C-terminal oligomerisation domain Mito_carr PF00153.22 CEP09710.1 - 5.3e-34 115.7 0.0 7.3e-22 76.8 0.1 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein AAA PF00004.24 CEP09712.1 - 2.8e-43 147.2 0.0 4.7e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CEP09712.1 - 2.6e-29 100.9 0.1 2.3e-28 97.8 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.1 CEP09712.1 - 9e-06 26.5 0.0 3.7e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP09712.1 - 1e-05 25.6 0.1 0.0014 18.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CEP09712.1 - 1.2e-05 25.1 0.0 8.7e-05 22.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CEP09712.1 - 2.8e-05 23.6 0.0 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein MIT PF04212.13 CEP09712.1 - 3.1e-05 23.7 0.6 0.00013 21.7 0.3 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_14 PF13173.1 CEP09712.1 - 3.4e-05 23.7 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEP09712.1 - 3.4e-05 22.9 0.0 7.8e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CEP09712.1 - 9e-05 22.6 0.2 0.0083 16.2 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.1 CEP09712.1 - 0.00015 21.8 0.0 0.00042 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CEP09712.1 - 0.00017 20.5 0.0 0.00087 18.2 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 CEP09712.1 - 0.00027 20.3 0.1 0.17 11.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 CEP09712.1 - 0.00035 19.4 0.0 0.00056 18.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CEP09712.1 - 0.00074 19.4 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CEP09712.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 CEP09712.1 - 0.0075 15.3 0.1 0.23 10.5 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 CEP09712.1 - 0.0099 15.4 0.1 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEP09712.1 - 0.011 16.0 2.5 0.013 15.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 CEP09712.1 - 0.012 15.4 0.0 0.081 12.7 0.0 2.0 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CEP09712.1 - 0.015 14.9 0.2 0.36 10.4 0.0 2.6 2 1 0 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 CEP09712.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PPV_E1_C PF00519.12 CEP09712.1 - 0.022 13.3 0.5 1.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase NACHT PF05729.7 CEP09712.1 - 0.027 14.1 0.0 0.43 10.2 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 CEP09712.1 - 0.028 13.5 0.0 0.062 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 CEP09712.1 - 0.04 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 CEP09712.1 - 0.045 12.9 0.0 0.096 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 CEP09712.1 - 0.051 12.6 0.0 5 6.1 0.0 2.3 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.12 CEP09712.1 - 0.061 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 CEP09712.1 - 0.1 12.9 0.1 0.97 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 CEP09712.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CEP09712.1 - 0.13 12.3 0.0 0.39 10.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 CEP09712.1 - 0.13 11.8 0.1 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TPR_1 PF00515.23 CEP09712.1 - 0.17 11.5 2.0 1.4 8.6 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_21 PF13304.1 CEP09712.1 - 0.23 11.4 0.4 2.6 7.9 0.0 2.3 2 1 1 3 3 2 0 AAA domain zf-C3HC4_2 PF13923.1 CEP09714.1 - 1.6e-08 34.4 13.9 1.6e-08 34.4 9.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 CEP09714.1 - 1.9e-07 30.9 0.1 6e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.1 CEP09714.1 - 1.2e-06 28.0 11.6 1.2e-06 28.0 8.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP09714.1 - 5.7e-06 26.0 11.4 1.1e-05 25.1 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCHC_3 PF13917.1 CEP09714.1 - 0.00036 20.2 0.3 0.00036 20.2 0.2 2.0 2 0 0 2 2 1 1 Zinc knuckle zf-RING_5 PF14634.1 CEP09714.1 - 0.00062 19.4 13.4 0.00062 19.4 9.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-CCHC PF00098.18 CEP09714.1 - 0.0024 17.7 1.8 0.0024 17.7 1.3 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 CEP09714.1 - 0.0038 16.6 3.8 0.0095 15.4 2.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-rbx1 PF12678.2 CEP09714.1 - 0.021 14.9 6.7 0.049 13.7 4.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CEP09714.1 - 0.026 14.2 4.1 0.043 13.6 2.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 CEP09714.1 - 3.8 7.2 21.4 0.058 13.0 9.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEP09714.1 - 7.8 6.4 18.8 0.44 10.4 9.2 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING NARG2_C PF10505.4 CEP09715.1 - 4.1e-12 45.7 0.0 7.2e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus NAF PF03822.9 CEP09715.1 - 0.087 12.5 0.1 0.28 10.9 0.1 1.9 1 0 0 1 1 1 0 NAF domain RVT_1 PF00078.22 CEP09716.1 - 4.7e-20 71.8 0.0 1.1e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP09716.1 - 2.2e-19 69.7 0.0 6.8e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP09716.1 - 5e-16 58.1 2.3 1.5e-15 56.5 1.6 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 CEP09716.1 - 4.1e-07 29.9 0.5 1.6e-05 24.9 0.1 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.5 CEP09716.1 - 0.0013 18.0 0.3 0.0032 16.8 0.2 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger E1-E2_ATPase PF00122.15 CEP09717.1 - 8.1e-59 198.4 1.3 8.1e-59 198.4 0.9 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEP09717.1 - 6.1e-20 72.5 0.0 2.7e-19 70.4 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP09717.1 - 1.2e-14 53.5 0.0 2.9e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEP09717.1 - 3.4e-12 46.9 0.0 7.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP09717.1 - 2.4e-05 24.0 0.3 4.9e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DDE_3 PF13358.1 CEP09718.1 - 1.4e-10 41.1 0.3 2.2e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP09718.1 - 5.3e-10 39.2 0.1 1e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Transposase FKBP_N PF01346.13 CEP09718.1 - 0.04 13.9 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Uso1_p115_head PF04869.9 CEP09719.1 - 2.3e-58 197.4 0.0 4.2e-58 196.5 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 CEP09719.1 - 3.7e-05 23.6 20.3 3.7e-05 23.6 14.0 1.8 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region FlxA PF14282.1 CEP09719.1 - 0.0015 18.4 20.0 0.0038 17.1 9.5 2.8 1 1 1 2 2 2 1 FlxA-like protein DUF2435 PF10363.4 CEP09719.1 - 0.02 14.7 0.9 6 6.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Macoilin PF09726.4 CEP09719.1 - 0.043 12.0 10.8 0.061 11.6 7.5 1.1 1 0 0 1 1 1 0 Transmembrane protein HAUS-augmin3 PF14932.1 CEP09719.1 - 0.071 12.2 15.3 0.14 11.3 10.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 CEP09719.1 - 0.16 11.5 23.2 26 4.3 15.7 2.6 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 CEP09719.1 - 0.71 9.6 20.7 3.2 7.4 5.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Med9 PF07544.8 CEP09719.1 - 0.71 9.6 11.3 0.22 11.2 0.4 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Nup54 PF13874.1 CEP09719.1 - 0.72 9.5 11.5 1.7 8.2 6.9 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ATG16 PF08614.6 CEP09719.1 - 0.91 9.3 19.7 0.21 11.3 6.0 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CEP09719.1 - 1.1 7.5 20.1 3.2 6.1 13.4 1.6 1 1 0 1 1 1 0 AAA domain ADIP PF11559.3 CEP09719.1 - 5.4 6.8 19.0 2.9 7.7 5.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 CEP09719.1 - 6.9 6.2 21.8 2.4 7.7 2.1 3.6 2 1 0 3 3 3 0 Septum formation initiator Tropomyosin_1 PF12718.2 CEP09719.1 - 7.5 6.3 25.3 3.3 7.5 15.5 1.9 1 1 1 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 CEP09719.1 - 8.6 6.2 25.7 15 5.5 3.2 3.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 CEP09719.1 - 9.3 6.6 15.8 4.4 7.7 3.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_5 PF07728.9 CEP09720.1 - 5.5e-131 431.1 0.3 2.5e-28 98.5 0.0 9.1 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CEP09720.1 - 2.7e-32 111.1 0.0 5.7e-08 32.4 0.0 6.8 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CEP09720.1 - 1.5e-28 99.6 0.1 0.00016 21.8 0.0 7.1 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEP09720.1 - 1.2e-24 87.4 0.0 0.011 16.5 0.0 8.2 6 0 0 6 6 6 5 AAA domain AAA_22 PF13401.1 CEP09720.1 - 6.4e-23 81.3 0.7 0.0027 17.8 0.0 8.2 7 0 0 7 7 7 5 AAA domain AAA_14 PF13173.1 CEP09720.1 - 2e-22 79.4 0.0 8.4e-05 22.4 0.0 7.8 6 1 0 7 7 7 4 AAA domain AAA_18 PF13238.1 CEP09720.1 - 1.2e-20 74.0 9.7 0.00085 19.6 0.0 8.4 7 0 0 7 7 6 5 AAA domain Sigma54_activ_2 PF14532.1 CEP09720.1 - 4e-20 72.2 0.6 5.1e-05 23.3 0.0 7.0 6 0 0 6 6 6 4 Sigma-54 interaction domain Sigma54_activat PF00158.21 CEP09720.1 - 5.4e-20 71.5 0.1 0.0017 17.8 0.0 6.9 6 1 0 6 6 6 5 Sigma-54 interaction domain AAA_16 PF13191.1 CEP09720.1 - 9.6e-20 71.3 10.3 0.0019 18.2 0.1 8.5 7 1 0 7 7 6 5 AAA ATPase domain AAA_33 PF13671.1 CEP09720.1 - 1e-17 64.3 0.7 0.21 11.4 0.0 7.9 6 1 0 6 6 6 4 AAA domain ABC_tran PF00005.22 CEP09720.1 - 7e-17 62.0 0.3 0.0036 17.6 0.0 7.8 6 0 0 6 6 6 3 ABC transporter UPF0079 PF02367.12 CEP09720.1 - 2.6e-14 52.9 3.4 0.075 12.6 0.0 6.7 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CEP09720.1 - 4.4e-13 49.5 3.7 0.35 10.8 0.0 7.0 6 0 0 6 6 6 3 AAA domain AAA_19 PF13245.1 CEP09720.1 - 1.1e-11 44.2 8.8 0.077 12.7 0.0 6.3 6 0 0 6 6 6 3 Part of AAA domain Miro PF08477.8 CEP09720.1 - 2.1e-11 44.3 3.7 3.2 8.2 0.0 7.5 7 0 0 7 7 6 1 Miro-like protein T2SE PF00437.15 CEP09720.1 - 2.6e-11 42.9 2.8 0.4 9.5 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein DUF258 PF03193.11 CEP09720.1 - 1.6e-10 40.3 2.7 1.2 8.3 0.0 6.4 6 0 0 6 6 6 3 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEP09720.1 - 3.6e-10 39.2 0.1 2.6 7.6 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain NACHT PF05729.7 CEP09720.1 - 7.2e-10 38.7 5.8 0.12 12.0 0.0 6.2 6 0 0 6 6 6 2 NACHT domain MobB PF03205.9 CEP09720.1 - 7.6e-10 38.6 1.6 0.4 10.3 0.0 6.5 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CEP09720.1 - 2.6e-09 37.2 7.1 0.51 10.5 0.0 8.0 8 0 0 8 8 7 2 RNA helicase AAA_25 PF13481.1 CEP09720.1 - 5.6e-09 35.6 1.6 0.5 9.7 0.0 5.8 5 0 0 5 5 5 3 AAA domain Mg_chelatase PF01078.16 CEP09720.1 - 1.2e-07 31.0 5.6 0.12 11.5 0.0 8.1 8 1 0 8 8 8 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 CEP09720.1 - 3.7e-07 29.7 5.3 0.036 13.5 0.0 5.9 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 CEP09720.1 - 5.1e-07 29.3 4.2 0.18 11.2 0.0 4.9 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain RuvB_N PF05496.7 CEP09720.1 - 1.7e-06 27.2 0.3 1.5 7.8 0.0 6.3 7 0 0 7 7 7 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 CEP09720.1 - 0.00015 21.5 3.3 3.8 7.1 0.1 5.3 5 0 0 5 5 4 1 NTPase KaiC PF06745.8 CEP09720.1 - 0.001 18.2 0.1 6.8 5.7 0.0 4.7 4 0 0 4 4 4 0 KaiC ATP-synt_ab PF00006.20 CEP09720.1 - 0.0012 18.3 0.0 6 6.2 0.0 4.3 5 0 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.1 CEP09720.1 - 0.0033 17.4 0.0 0.52 10.2 0.0 4.1 4 0 0 4 4 4 1 AAA domain S-AdoMet_synt_C PF02773.11 CEP09720.1 - 0.029 14.0 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 1 0 S-adenosylmethionine synthetase, C-terminal domain Arrestin_C PF02752.17 CEP09721.1 - 8.2e-07 29.2 3.4 1e-06 28.9 0.9 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DDE_3 PF13358.1 CEP09722.1 - 3.1e-29 101.6 0.0 5.6e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP09722.1 - 2.2e-05 24.5 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP09722.1 - 2.8e-05 24.0 0.4 5.7e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP09722.1 - 0.00076 20.2 0.0 0.003 18.3 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 CEP09722.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.21 CEP09722.1 - 0.11 12.5 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain HTH_17 PF12728.2 CEP09722.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HA2 PF04408.18 CEP09724.1 - 5.2e-20 71.3 1.8 6.4e-20 71.0 0.2 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEP09724.1 - 2.6e-12 46.4 0.0 6.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP09724.1 - 1.1e-08 34.8 0.0 2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CEP09724.1 - 6.9e-07 29.0 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CEP09724.1 - 8.4e-05 22.7 0.2 0.00044 20.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CEP09724.1 - 0.00033 19.6 0.1 0.0014 17.5 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 CEP09724.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CEP09724.1 - 0.012 15.4 3.3 0.048 13.4 0.1 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 CEP09724.1 - 0.018 14.5 0.1 7 6.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Miro PF08477.8 CEP09724.1 - 0.026 15.0 1.2 0.11 12.9 0.0 2.6 3 0 0 3 3 3 0 Miro-like protein PhoH PF02562.11 CEP09724.1 - 0.034 13.3 0.0 0.11 11.6 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 CEP09724.1 - 0.036 13.6 4.4 26 4.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 CEP09724.1 - 0.048 13.5 0.3 1.1 9.1 0.1 2.9 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.1 CEP09724.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CEP09724.1 - 3.2 8.0 5.0 0.56 10.4 0.1 2.3 3 1 0 3 3 2 0 ABC transporter AAA_11 PF13086.1 CEP09725.1 - 3.4e-29 102.1 0.2 1e-28 100.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CEP09725.1 - 1.2e-27 96.6 0.0 2.8e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP09725.1 - 2.2e-10 40.1 0.1 8.5e-09 35.0 0.0 2.8 3 0 0 3 3 3 1 Part of AAA domain DEAD PF00270.24 CEP09725.1 - 1.5e-06 27.8 0.0 3.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.1 CEP09725.1 - 2.7e-06 27.0 0.0 0.022 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CEP09725.1 - 0.00037 19.9 0.0 0.001 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CEP09725.1 - 0.00067 19.5 0.0 0.0023 17.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CEP09725.1 - 0.0024 17.1 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein UvrD_C_2 PF13538.1 CEP09725.1 - 0.0029 17.7 0.1 0.0077 16.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 CEP09725.1 - 0.003 17.7 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 CEP09725.1 - 0.0031 16.5 0.5 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 CEP09725.1 - 0.0055 16.9 0.0 0.025 14.7 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.16 CEP09725.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein TFIID-18kDa PF02269.11 CEP09726.1 - 2.9e-28 97.5 0.2 3.7e-28 97.1 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Pex2_Pex12 PF04757.9 CEP09727.1 - 8.1e-37 126.8 4.0 1.2e-36 126.3 2.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CEP09727.1 - 0.00046 19.9 5.9 0.0015 18.2 4.1 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CEP09727.1 - 0.00058 19.4 6.2 0.0011 18.5 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEP09727.1 - 0.0048 16.7 3.7 0.0048 16.7 2.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CEP09727.1 - 0.0066 16.1 6.6 0.016 14.8 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CEP09727.1 - 0.0089 16.0 6.1 0.09 12.8 4.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP09727.1 - 0.021 14.5 0.3 0.081 12.6 0.2 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 CEP09727.1 - 0.035 14.1 1.6 0.069 13.2 1.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Mpv17_PMP22 PF04117.7 CEP09727.1 - 0.067 12.8 1.1 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Mpv17 / PMP22 family DUF4119 PF13494.1 CEP09728.1 - 0.19 11.7 3.1 1.6 8.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) EHN PF06441.7 CEP09729.1 - 2.6e-31 107.8 3.2 5e-31 106.9 2.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CEP09729.1 - 3.8e-17 62.9 0.0 7.8e-17 61.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP09729.1 - 9.3e-07 28.6 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP09729.1 - 0.0007 19.3 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_1 PF00175.16 CEP09730.1 - 1.9e-26 92.7 0.0 1.9e-26 92.7 0.0 3.9 2 1 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEP09730.1 - 8.3e-14 51.5 0.0 3.5e-13 49.5 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CEP09730.1 - 0.0038 17.1 0.0 0.0038 17.1 0.0 5.0 3 2 1 4 4 4 2 Ferric reductase NAD binding domain Cep57_CLD_2 PF14197.1 CEP09731.1 - 0.008 16.1 0.5 0.008 16.1 0.3 4.9 7 0 0 7 7 7 1 Centrosome localisation domain of PPC89 HAP1_N PF04849.8 CEP09731.1 - 0.01 14.8 25.3 0.011 14.7 15.7 2.1 1 1 0 1 1 1 0 HAP1 N-terminal conserved region NPV_P10 PF05531.7 CEP09731.1 - 0.2 11.9 12.3 0.56 10.4 0.1 4.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein SPX PF03105.14 CEP09731.1 - 0.4 10.4 14.1 0.79 9.4 9.5 1.9 1 1 0 1 1 1 0 SPX domain PspA_IM30 PF04012.7 CEP09731.1 - 2.7 7.3 26.4 27 4.0 0.7 3.2 1 1 1 2 2 2 0 PspA/IM30 family Glycoprotein PF03409.10 CEP09733.1 - 0.033 12.9 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein CotH PF08757.6 CEP09735.1 - 4e-39 134.7 2.9 6.3e-39 134.1 2.0 1.3 1 0 0 1 1 1 1 CotH protein Fungal_trans PF04082.13 CEP09736.1 - 5.8e-43 146.6 0.1 1.1e-42 145.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP09736.1 - 3.4e-11 42.8 8.9 3.4e-11 42.8 6.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.13 CEP09737.1 - 1.3e-12 47.4 0.0 1.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP09737.1 - 0.00033 20.3 0.1 0.00046 19.8 0.1 1.2 1 0 0 1 1 1 1 Barwin family DUF3039 PF11238.3 CEP09737.1 - 0.17 11.3 0.5 0.37 10.2 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3039) Methyltransf_7 PF03492.10 CEP09739.1 - 0.026 13.2 0.1 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Metallophos PF00149.23 CEP09740.1 - 8.5e-40 136.2 0.9 1.3e-39 135.6 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 CEP09740.1 - 0.0053 16.7 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region DUF2313 PF10076.4 CEP09740.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) Acyltransferase PF01553.16 CEP09741.1 - 9.6e-09 34.7 0.0 6.3e-08 32.1 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase SNF2_N PF00176.18 CEP09742.1 - 7.6e-76 254.7 0.0 1.3e-75 253.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP09742.1 - 1.3e-16 60.2 0.0 5.9e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HIRAN PF08797.6 CEP09742.1 - 1.7e-12 47.1 0.0 3.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 CEP09742.1 - 6e-09 35.6 0.0 1.7e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 CEP09742.1 - 2.5e-06 27.4 5.3 7.5e-06 25.8 3.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP09742.1 - 2.9e-06 26.9 7.0 6.1e-06 25.9 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.10 CEP09742.1 - 1.7e-05 24.7 0.0 7.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CUE PF02845.11 CEP09742.1 - 5.3e-05 22.5 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 CEP09742.1 - 6.4e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain zf-C3HC4_3 PF13920.1 CEP09742.1 - 0.0002 20.9 5.0 0.00049 19.7 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP09742.1 - 0.00061 19.3 4.8 0.0024 17.4 3.3 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP09742.1 - 0.00062 19.4 7.1 0.0015 18.2 4.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CEP09742.1 - 1.7 8.4 8.1 0.26 11.0 2.0 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CEP09742.1 - 2.8 7.8 10.0 1.3 8.9 4.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING GFA PF04828.9 CEP09744.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme IncFII_repA PF02387.10 CEP09745.1 - 0.48 9.5 16.1 1 8.4 11.1 1.6 1 0 0 1 1 1 0 IncFII RepA protein family Mnd1 PF03962.10 CEP09745.1 - 0.74 9.4 0.0 0.74 9.4 0.0 2.4 2 1 0 2 2 2 0 Mnd1 family Asp-B-Hydro_N PF05279.6 CEP09745.1 - 3.5 7.4 36.2 1.6 8.5 21.0 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PSP1 PF04468.7 CEP09746.1 - 3e-33 113.6 2.7 3.8e-32 110.1 2.8 2.0 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Pox_A3L PF05288.6 CEP09746.1 - 0.014 15.0 0.2 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A3L Protein DRMBL PF07522.9 CEP09747.1 - 0.00015 21.7 0.1 0.00059 19.8 0.1 2.1 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Abhydrolase_6 PF12697.2 CEP09748.1 - 3.1e-20 73.0 0.0 6.1e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP09748.1 - 1.1e-12 48.0 0.0 2.2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP09748.1 - 1.6e-09 37.6 0.0 1.4e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methylase_S PF01420.14 CEP09748.1 - 0.033 14.1 0.3 0.062 13.2 0.2 1.4 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Abp2 PF09441.5 CEP09749.1 - 3e-20 72.8 0.1 7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 ARS binding protein 2 KH_1 PF00013.24 CEP09750.1 - 2.2e-18 65.6 0.0 5e-06 26.0 0.0 6.3 6 0 0 6 6 6 5 KH domain KH_3 PF13014.1 CEP09750.1 - 1.5e-11 43.6 0.3 1.7e-05 24.3 0.0 5.0 6 0 0 6 6 6 2 KH domain SLS PF14611.1 CEP09750.1 - 2.4e-07 30.3 3.7 0.0024 17.3 0.2 4.0 4 0 0 4 4 4 2 Mitochondrial inner-membrane-bound regulator TylF PF05711.6 CEP09751.1 - 0.092 11.7 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) MOZ_SAS PF01853.13 CEP09752.1 - 1.8e-48 164.3 0.2 2.3e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.1 CEP09752.1 - 0.031 14.4 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RVT PF13966.1 CEP09753.1 - 0.0048 17.1 0.3 0.0084 16.3 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase WD40 PF00400.27 CEP09754.1 - 8.1e-54 177.7 19.9 8e-09 35.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CEP09754.1 - 0.14 10.4 0.0 0.37 9.0 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ribonuc_L-PSP PF01042.16 CEP09755.1 - 2e-47 159.9 0.7 2.2e-47 159.7 0.5 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sel1 PF08238.7 CEP09756.1 - 3.1e-35 119.8 24.5 2.3e-10 40.7 0.8 7.1 7 0 0 7 7 7 6 Sel1 repeat TPR_11 PF13414.1 CEP09756.1 - 0.0032 17.0 6.0 0.077 12.6 0.1 3.7 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 CEP09756.1 - 0.0058 16.4 6.0 1.4 9.0 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP09756.1 - 0.0096 15.6 0.8 8.9 6.3 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP09756.1 - 0.026 15.2 5.7 11 6.8 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEP09756.1 - 0.032 14.8 3.1 0.61 10.8 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP09756.1 - 0.039 13.9 2.5 3.1 7.8 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat SUI1 PF01253.17 CEP09756.1 - 0.14 11.9 1.6 0.15 11.8 0.2 1.8 2 0 0 2 2 2 0 Translation initiation factor SUI1 TPR_8 PF13181.1 CEP09756.1 - 0.97 9.3 4.3 18 5.4 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP09756.1 - 1.4 8.6 8.6 10 5.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 CEP09756.1 - 2.4 8.5 5.4 14 6.0 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat MMR_HSR1 PF01926.18 CEP09757.1 - 7.8e-18 64.5 0.2 1.5e-15 57.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP09757.1 - 1.8e-06 27.3 0.2 2.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CEP09757.1 - 1.3e-05 24.4 0.1 3.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CEP09757.1 - 0.00012 21.3 3.8 0.00022 20.4 0.0 2.4 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 CEP09757.1 - 0.0036 17.1 8.8 0.023 14.5 0.0 3.6 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 CEP09757.1 - 0.082 13.4 3.5 0.11 12.9 0.0 2.9 3 0 0 3 3 3 0 Miro-like protein DUF4193 PF13834.1 CEP09757.1 - 5.2 7.3 11.4 2.6 8.2 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4193) Aminotran_1_2 PF00155.16 CEP09758.1 - 5.5e-26 91.3 0.0 6.1e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II 5_nucleotid PF05761.9 CEP09759.1 - 3.2e-89 299.5 8.9 2.6e-65 220.7 0.1 4.0 1 1 2 3 3 3 3 5' nucleotidase family Drc1-Sld2 PF11719.3 CEP09762.1 - 9e-12 44.7 9.0 9e-12 44.7 6.2 3.1 2 1 1 3 3 3 2 DNA replication and checkpoint protein ACDC PF14733.1 CEP09762.1 - 0.16 12.0 1.9 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 AP2-coincident C-terminal DUF3245 PF11595.3 CEP09762.1 - 1.1 9.5 12.8 0.091 13.0 4.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF3332 PF11810.3 CEP09762.1 - 9.5 5.8 9.4 2.5 7.7 2.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3332) OrfB_Zn_ribbon PF07282.6 CEP09763.1 - 0.21 11.2 1.1 0.3 10.7 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Nucleoside_tran PF01733.13 CEP09764.1 - 3.5e-54 184.0 18.3 9.1e-54 182.7 11.5 2.3 1 1 1 2 2 2 2 Nucleoside transporter AA_permease_2 PF13520.1 CEP09765.1 - 1e-56 192.3 57.3 1.3e-56 191.9 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP09765.1 - 1.6e-38 132.2 51.3 2.1e-38 131.8 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 CEP09765.1 - 3.9e-06 26.6 5.9 3.9e-06 26.6 4.1 4.0 3 0 0 3 3 3 1 C-terminus of AA_permease IncA PF04156.9 CEP09766.1 - 0.00012 21.7 0.3 0.00016 21.3 0.2 1.1 1 0 0 1 1 1 1 IncA protein DUF3552 PF12072.3 CEP09766.1 - 0.013 14.6 0.4 0.017 14.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tantalus PF15386.1 CEP09766.1 - 0.026 14.2 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Drosophila Tantalus-like Sugarporin_N PF11471.3 CEP09766.1 - 0.58 9.8 5.8 1.3 8.7 4.0 1.6 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Peptidase_M28 PF04389.12 CEP09767.1 - 6.6e-35 120.4 0.0 9.7e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 zf-met PF12874.2 CEP09768.1 - 0.00099 19.2 0.7 0.0025 17.9 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CEP09768.1 - 0.0073 16.5 2.5 0.015 15.6 1.8 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CEP09768.1 - 0.032 14.3 0.9 0.054 13.6 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEP09768.1 - 0.12 12.3 2.9 0.19 11.7 2.0 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Rap_GAP PF02145.10 CEP09769.1 - 2.2e-50 170.6 0.0 4.2e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP HTH_Tnp_Tc3_1 PF11427.3 CEP09769.1 - 0.02 14.4 0.1 0.079 12.6 0.0 2.0 1 0 0 1 1 1 0 Tc3 transposase DUF3220 PF11516.3 CEP09769.1 - 0.022 14.7 0.0 0.094 12.6 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Na_trans_assoc PF06512.8 CEP09770.1 - 0.2 11.6 2.0 0.22 11.4 1.4 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated rve PF00665.21 CEP09771.1 - 2.8e-05 24.1 0.0 8.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.12 CEP09774.1 - 0.01 15.8 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Abi_2 PF07751.6 CEP09774.1 - 0.021 15.0 0.4 0.076 13.1 0.0 2.0 2 0 0 2 2 2 0 Abi-like protein zf-RVT PF13966.1 CEP09776.1 - 0.00012 22.2 0.3 0.00023 21.4 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.13 CEP09777.1 - 7.4e-07 29.1 0.0 1.9e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Transposase HlyIII PF03006.15 CEP09778.1 - 1.5e-58 197.8 22.7 1.9e-58 197.5 15.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 CEP09778.1 - 0.025 14.5 1.4 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Ras PF00071.17 CEP09779.1 - 4.6e-30 104.1 0.2 5.5e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP09779.1 - 1e-20 74.4 0.1 4.6e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP09779.1 - 3.4e-06 26.4 0.0 4.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP09779.1 - 0.00019 20.6 0.1 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP09779.1 - 0.00035 20.0 0.1 0.0063 15.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP09779.1 - 0.0099 15.8 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CEP09779.1 - 0.1 12.7 0.0 0.43 10.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain DPBB_1 PF03330.13 CEP09780.1 - 2.7e-14 52.9 0.0 3.5e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP09780.1 - 0.016 14.9 0.1 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Barwin family Pkinase PF00069.20 CEP09782.1 - 4e-64 216.2 0.0 6.3e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09782.1 - 2.7e-50 170.8 0.0 4.7e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.12 CEP09782.1 - 6.4e-06 25.9 0.1 2e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.1 CEP09782.1 - 1.2e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 CEP09782.1 - 1.4e-05 24.2 0.0 0.0071 15.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like SAM_1 PF00536.25 CEP09782.1 - 0.00011 22.2 0.1 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kdo PF06293.9 CEP09782.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.12 CEP09783.1 - 8e-43 146.1 0.1 9e-43 145.9 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family E1-E2_ATPase PF00122.15 CEP09786.1 - 5.2e-58 195.7 11.6 5.2e-58 195.7 8.0 2.4 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CEP09786.1 - 1.4e-29 104.0 0.7 3.3e-29 102.8 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP09786.1 - 3e-14 53.6 0.0 6.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP09786.1 - 5.2e-09 35.4 0.0 1.6e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP09786.1 - 0.0011 18.5 0.1 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP09786.1 - 0.0037 17.1 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit LPAM_1 PF08139.7 CEP09786.1 - 0.1 12.8 1.4 0.57 10.4 1.0 2.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site ABC_membrane PF00664.18 CEP09787.1 - 9.5e-58 195.7 24.3 1.9e-34 119.3 4.6 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP09787.1 - 3.2e-48 163.5 0.0 4.4e-28 98.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CEP09787.1 - 4e-09 36.8 1.2 0.00094 19.2 0.1 4.9 3 2 1 4 4 4 2 AAA domain SMC_N PF02463.14 CEP09787.1 - 3.2e-07 29.7 10.6 0.0026 17.0 2.1 4.4 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CEP09787.1 - 1.6e-06 27.5 0.2 0.019 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CEP09787.1 - 6.7e-06 25.6 0.1 0.098 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 CEP09787.1 - 1e-05 24.5 0.0 0.029 13.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CEP09787.1 - 1.9e-05 24.2 0.0 0.036 13.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 CEP09787.1 - 0.00012 22.4 8.0 0.016 15.5 0.0 3.7 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 CEP09787.1 - 0.00036 21.0 0.3 0.11 12.9 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 CEP09787.1 - 0.00072 19.5 1.2 0.88 9.5 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CEP09787.1 - 0.0013 18.8 2.0 0.98 9.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP09787.1 - 0.0013 19.4 3.5 1.9 9.3 0.7 3.5 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.12 CEP09787.1 - 0.0042 16.9 1.7 0.51 10.1 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CEP09787.1 - 0.0058 16.5 0.3 4.5 7.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CEP09787.1 - 0.0067 15.5 0.0 0.41 9.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 CEP09787.1 - 0.0068 15.6 0.3 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 CEP09787.1 - 0.0071 16.2 1.0 0.23 11.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CEP09787.1 - 0.0079 16.0 2.1 0.077 12.8 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 CEP09787.1 - 0.01 15.3 2.3 1.8 7.9 0.1 2.6 2 1 1 3 3 3 0 AAA-like domain MobB PF03205.9 CEP09787.1 - 0.014 15.1 0.2 6.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 CEP09787.1 - 0.018 14.8 0.5 0.12 12.1 0.1 2.4 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CEP09787.1 - 0.028 14.5 0.0 5.1 7.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 CEP09787.1 - 0.03 14.6 2.2 7.6 6.8 0.1 3.3 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 CEP09787.1 - 0.033 13.7 0.9 5.5 6.4 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TMEM190 PF15431.1 CEP09787.1 - 0.042 13.7 2.2 0.14 12.1 0.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 190 Ninjurin PF04923.7 CEP09787.1 - 0.064 12.9 1.2 0.22 11.2 0.1 2.6 2 0 0 2 2 1 0 Ninjurin NACHT PF05729.7 CEP09787.1 - 0.13 11.9 0.2 11 5.7 0.0 2.9 2 0 0 2 2 2 0 NACHT domain DUF1049 PF06305.6 CEP09787.1 - 0.18 11.3 3.8 6.2 6.3 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) HTH_Tnp_Tc3_2 PF01498.13 CEP09788.1 - 1.4e-07 31.4 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Transposase Fumerase PF05681.9 CEP09788.1 - 0.017 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) HTH_29 PF13551.1 CEP09789.1 - 0.0074 16.4 0.0 0.0091 16.1 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP09789.1 - 0.0099 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 CEP09789.1 - 0.05 13.2 0.0 0.096 12.3 0.0 1.7 1 1 0 1 1 1 0 MarR family Fe_dep_repress PF01325.14 CEP09789.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Mad3_BUB1_I PF08311.7 CEP09790.1 - 4.6e-38 129.8 1.3 8.1e-38 129.0 0.9 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Vps35 PF03635.12 CEP09791.1 - 4.8e-254 845.0 19.8 5.8e-254 844.8 13.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TRAP_alpha PF03896.11 CEP09791.1 - 0.015 14.3 2.6 0.025 13.5 1.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.10 CEP09791.1 - 0.019 13.6 2.5 0.03 13.0 1.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.1 CEP09791.1 - 0.023 12.8 2.4 0.036 12.2 1.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AIF_C PF14721.1 CEP09791.1 - 0.1 12.8 2.6 0.25 11.6 1.8 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CobT PF06213.7 CEP09791.1 - 1.2 8.1 10.6 2 7.4 7.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Band_3_cyto PF07565.8 CEP09791.1 - 2 7.8 9.6 0.27 10.6 3.7 1.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EF-hand_1 PF00036.27 CEP09792.1 - 1.5e-41 136.5 12.1 2e-10 39.2 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEP09792.1 - 3.3e-36 123.2 4.2 4.6e-21 74.7 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CEP09792.1 - 6.9e-34 115.2 12.1 1.9e-16 59.4 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CEP09792.1 - 2.4e-31 104.7 7.3 1.5e-09 36.9 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CEP09792.1 - 2.3e-26 89.8 8.5 9.7e-07 27.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CEP09792.1 - 1.6e-13 50.3 0.1 3.4e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CEP09792.1 - 1.5e-10 41.1 0.0 3e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEP09792.1 - 1.9e-10 40.3 1.1 0.00013 21.6 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 CEP09792.1 - 1e-06 28.6 2.5 1.3e-05 25.0 0.4 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_like PF09279.6 CEP09792.1 - 0.00013 21.8 2.8 0.00097 19.1 0.2 2.8 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like UPF0154 PF03672.8 CEP09792.1 - 0.00014 21.3 0.9 0.036 13.6 0.0 3.6 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) TerB PF05099.8 CEP09792.1 - 0.00056 19.6 2.5 0.2 11.3 0.0 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB DUF3349 PF11829.3 CEP09792.1 - 0.004 17.5 0.6 2.7 8.4 0.0 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF2267 PF10025.4 CEP09792.1 - 0.007 16.4 0.0 0.13 12.3 0.0 2.4 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) Tenui_NCP PF04876.7 CEP09792.1 - 0.0092 15.5 0.5 0.82 9.1 0.0 2.1 1 1 1 2 2 2 2 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 CEP09792.1 - 0.012 15.6 2.8 0.95 9.4 0.2 2.7 2 1 1 3 3 3 0 RNA polymerase Rpb4 Caleosin PF05042.8 CEP09792.1 - 0.013 15.0 0.2 0.83 9.1 0.1 2.6 1 1 0 1 1 1 0 Caleosin related protein DUF853 PF05872.7 CEP09792.1 - 0.024 13.0 0.1 0.2 9.9 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Fe_hyd_lg_C PF02906.9 CEP09792.1 - 0.069 12.3 1.4 0.22 10.7 1.0 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain YqeY PF09424.5 CEP09792.1 - 0.072 12.9 0.9 0.64 9.8 0.3 2.1 1 1 1 2 2 2 0 Yqey-like protein OST-HTH PF12872.2 CEP09792.1 - 0.073 12.9 0.0 8.3 6.3 0.0 3.3 2 1 1 3 3 3 0 OST-HTH/LOTUS domain DUF4497 PF14924.1 CEP09792.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) CMD PF02627.15 CEP09792.1 - 0.15 11.9 0.9 2.3 8.1 0.0 2.9 3 1 0 3 3 3 0 Carboxymuconolactone decarboxylase family DUF3650 PF12368.3 CEP09792.1 - 0.15 11.5 3.5 25 4.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) Acyl-CoA_dh_1 PF00441.19 CEP09794.1 - 1.5e-23 83.5 0.4 2.9e-23 82.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CEP09794.1 - 3.7e-08 33.7 0.0 7.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEP09794.1 - 5.7e-08 32.1 0.1 1e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CEP09794.1 - 0.1 13.1 0.1 0.4 11.2 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain DUF3897 PF13036.1 CEP09795.1 - 0.013 15.1 0.2 0.016 14.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) TYA PF01021.14 CEP09795.1 - 0.041 14.0 0.6 0.05 13.8 0.4 1.2 1 0 0 1 1 1 0 TYA transposon protein SRP9-21 PF05486.7 CEP09796.1 - 1.8e-19 69.2 0.8 2.5e-19 68.7 0.6 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Sir1 PF11603.3 CEP09796.1 - 0.045 13.9 0.2 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Regulatory protein Sir1 SET PF00856.23 CEP09797.1 - 1.5e-20 74.1 0.4 3.3e-20 73.0 0.3 1.6 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 CEP09797.1 - 2.1e-11 43.8 1.2 2.1e-11 43.8 0.8 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DAP PF15228.1 CEP09797.1 - 0.051 14.3 1.7 0.14 12.8 1.2 1.7 1 0 0 1 1 1 0 Death-associated protein FAM176 PF14851.1 CEP09797.1 - 0.1 12.2 7.1 0.027 14.1 2.5 1.8 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 CEP09797.1 - 0.21 11.0 12.9 0.4 10.1 8.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CEP09797.1 - 3.6 7.9 11.9 7.2 6.9 8.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PseudoU_synth_1 PF01416.15 CEP09798.1 - 9.9e-30 103.0 0.0 1.3e-16 60.9 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase PHD PF00628.24 CEP09800.1 - 2.5e-10 39.8 12.5 2.5e-10 39.8 8.7 1.9 2 0 0 2 2 2 1 PHD-finger SET PF00856.23 CEP09800.1 - 1.6e-05 25.2 0.0 1.6e-05 25.2 0.0 4.0 2 2 0 2 2 2 1 SET domain PHD_2 PF13831.1 CEP09800.1 - 0.009 15.3 6.4 0.02 14.2 4.4 1.5 1 0 0 1 1 1 1 PHD-finger ArgJ PF01960.13 CEP09801.1 - 5.7e-151 502.3 1.7 6.5e-151 502.1 1.2 1.0 1 0 0 1 1 1 1 ArgJ family FYRN PF05964.9 CEP09801.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 F/Y-rich N-terminus DNA_pol_B PF00136.16 CEP09802.1 - 1.4e-145 485.6 1.4 2.3e-145 484.9 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CEP09802.1 - 9.4e-88 294.1 0.1 1.8e-86 289.9 0.0 2.7 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CEP09802.1 - 2.9e-23 81.6 7.2 7.5e-23 80.3 5.0 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CEP09802.1 - 5.1e-05 22.1 0.9 0.0023 16.6 0.1 2.3 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral HD_2 PF12917.2 CEP09802.1 - 0.0018 18.1 0.6 0.0082 15.9 0.2 2.1 2 0 0 2 2 2 1 HD containing hydrolase-like enzyme RNase_H_2 PF13482.1 CEP09802.1 - 0.0027 17.5 0.1 0.011 15.5 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 CEP09802.1 - 0.0066 15.9 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-RING-like PF08746.6 CEP09802.1 - 0.031 14.2 0.8 0.1 12.6 0.5 1.9 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.17 CEP09802.1 - 0.35 10.6 7.0 1.4 8.7 4.9 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L1 PF00687.16 CEP09803.1 - 2.5e-31 108.7 1.0 2.9e-31 108.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MRL1 PF13003.2 CEP09803.1 - 0.00017 21.4 0.0 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L1 Ribosomal_L5_C PF00673.16 CEP09804.1 - 2.1e-25 88.2 0.0 3.5e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CEP09804.1 - 1.2e-06 28.1 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 LCAT PF02450.10 CEP09805.1 - 3.8e-67 226.9 0.0 5.4e-64 216.5 0.2 2.3 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 CEP09805.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Kinesin PF00225.18 CEP09806.1 - 1.5e-82 277.0 1.4 1.7e-77 260.3 0.7 2.7 2 1 1 3 3 3 2 Kinesin motor domain DUF641 PF04859.7 CEP09806.1 - 0.13 12.0 8.2 0.064 13.0 1.9 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Thaumatin PF00314.12 CEP09807.1 - 5.3e-51 173.1 13.9 7.6e-51 172.5 9.6 1.2 1 0 0 1 1 1 1 Thaumatin family Fungal_trans PF04082.13 CEP09808.1 - 4.7e-13 48.6 1.9 4.7e-13 48.6 1.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP09808.1 - 1.5e-05 24.8 9.0 3.3e-05 23.6 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 CEP09808.1 - 4.1 6.6 22.8 0.99 8.7 11.6 2.2 2 0 0 2 2 2 0 Vta1 like MLANA PF14991.1 CEP09809.1 - 0.028 14.4 0.0 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein melan-A TMEM169 PF15052.1 CEP09809.1 - 0.061 13.2 0.9 0.12 12.2 0.6 1.6 1 0 0 1 1 1 0 TMEM169 protein family Enoyl_reductase PF12241.3 CEP09809.1 - 0.069 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region LRR_8 PF13855.1 CEP09810.1 - 1e-22 79.6 33.4 1.9e-11 43.5 4.0 3.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CEP09810.1 - 2e-16 59.2 15.6 1e-10 40.9 0.3 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP09810.1 - 6.3e-12 43.7 17.5 0.001 18.7 0.5 5.6 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.1 CEP09810.1 - 7.8e-08 31.6 11.3 0.022 14.8 0.3 4.8 4 0 0 4 4 4 3 Leucine Rich repeat LRR_7 PF13504.1 CEP09810.1 - 1.6e-06 27.3 14.7 0.11 12.8 0.7 5.3 5 0 0 5 5 5 2 Leucine rich repeat DUF3812 PF12757.2 CEP09810.1 - 0.0015 18.5 0.2 0.0041 17.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3812) SelR PF01641.13 CEP09810.1 - 0.033 13.8 0.1 0.086 12.5 0.0 1.6 2 0 0 2 2 2 0 SelR domain LRR_9 PF14580.1 CEP09810.1 - 0.052 13.1 1.3 0.13 11.8 0.9 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_3 PF07725.7 CEP09810.1 - 0.51 10.1 6.3 2.1 8.2 0.7 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat MFS_1 PF07690.11 CEP09811.1 - 4e-46 157.3 32.2 1.8e-45 155.2 16.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP09811.1 - 2.6e-05 22.9 34.9 0.00015 20.4 24.1 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Transgly_assoc PF04226.8 CEP09811.1 - 0.7 10.0 6.4 1.7 8.8 2.3 2.9 2 0 0 2 2 2 0 Transglycosylase associated protein Glyco_hydro_16 PF00722.16 CEP09812.1 - 3.8e-25 88.2 0.8 2.3e-24 85.6 0.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Band_7 PF01145.20 CEP09813.1 - 3.7e-25 88.8 3.0 4.2e-25 88.6 1.7 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 CEP09813.1 - 0.0091 15.3 1.6 0.012 14.9 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2884) PIG-X PF08320.7 CEP09814.1 - 5.6e-31 107.4 0.8 1.2e-30 106.3 0.6 1.5 1 1 0 1 1 1 1 PIG-X / PBN1 VHS PF00790.14 CEP09815.1 - 1.9e-39 134.4 2.6 1.4e-38 131.7 0.0 2.8 3 0 0 3 3 3 1 VHS domain FYVE PF01363.16 CEP09815.1 - 3.6e-09 36.3 7.4 7.3e-09 35.4 5.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.9 CEP09815.1 - 0.00031 20.6 0.5 0.0011 18.8 0.4 2.0 1 0 0 1 1 1 1 GAT domain Hrs_helical PF12210.3 CEP09815.1 - 0.0012 19.0 0.6 0.0012 19.0 0.4 2.5 3 0 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.15 CEP09815.1 - 0.0013 18.1 6.9 0.16 11.6 1.8 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif HypA PF01155.14 CEP09815.1 - 0.059 13.0 0.2 0.38 10.4 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C3HC4_2 PF13923.1 CEP09815.1 - 0.58 10.2 5.9 1.4 9.0 4.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nop14 PF04147.7 CEP09816.1 - 3.3 5.5 9.7 5.4 4.8 6.7 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CEP09816.1 - 3.3 6.9 10.0 5 6.3 6.9 1.2 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.22 CEP09817.1 - 2e-06 27.3 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MSA-2c PF12238.3 CEP09818.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c HAMP PF00672.20 CEP09819.1 - 9e-54 179.5 16.1 1.6e-09 37.8 0.1 6.5 6 0 0 6 6 6 6 HAMP domain HTH_6 PF01418.12 CEP09819.1 - 1.7e-05 24.4 0.2 20 4.9 0.0 5.8 5 0 0 5 5 5 0 Helix-turn-helix domain, rpiR family GrpE PF01025.14 CEP09819.1 - 0.0002 20.9 0.0 0.83 9.1 0.0 4.2 1 1 3 5 5 5 1 GrpE ImcF-related_N PF14331.1 CEP09819.1 - 0.00025 20.0 0.1 1.3 7.8 0.0 4.1 4 1 1 5 5 5 1 ImcF-related N-terminal domain SpoIIID PF12116.3 CEP09819.1 - 0.013 15.3 1.4 69 3.4 0.0 5.1 5 0 0 5 5 5 0 Stage III sporulation protein D DUF948 PF06103.6 CEP09819.1 - 0.057 13.2 25.8 4.1 7.3 0.5 7.5 6 4 1 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF1370 PF07114.6 CEP09819.1 - 0.083 12.0 2.9 64 2.6 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1370) Vps52 PF04129.7 CEP09819.1 - 0.27 9.7 1.5 32 2.8 0.0 4.0 5 0 0 5 5 5 0 Vps52 / Sac2 family DUF2365 PF10157.4 CEP09819.1 - 1.1 9.1 14.9 42 3.9 0.1 6.0 5 3 0 5 5 5 0 Uncharacterized conserved protein (DUF2365) VBS PF08913.5 CEP09819.1 - 1.9 8.7 15.1 12 6.2 0.1 5.2 3 2 1 5 5 5 0 Vinculin Binding Site CENP-F_leu_zip PF10473.4 CEP09819.1 - 2.7 7.8 11.9 29 4.4 0.1 5.1 5 0 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1725 PF08333.6 CEP09819.1 - 4 6.8 9.2 21 4.5 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1725) rve PF00665.21 CEP09820.1 - 1.7e-06 28.1 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain BRK PF07533.11 CEP09821.1 - 0.19 11.2 0.8 9 5.8 0.0 3.5 4 0 0 4 4 4 0 BRK domain PDZ_1 PF12812.2 CEP09822.1 - 1.9e-42 143.0 0.0 4.6e-30 103.3 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 CEP09822.1 - 1e-15 57.3 0.1 1.2e-07 31.5 0.0 4.6 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 CEP09822.1 - 1.6e-09 37.7 0.0 8.7e-05 22.6 0.0 3.7 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.1 CEP09822.1 - 1e-06 28.7 1.1 0.025 14.5 0.0 2.9 2 0 0 2 2 2 2 Trypsin-like peptidase domain Tricorn_PDZ PF14685.1 CEP09822.1 - 0.0037 17.0 0.1 0.07 12.9 0.0 2.8 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 CEP09822.1 - 0.073 12.4 0.2 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 CEP09822.1 - 0.18 11.1 0.2 0.24 10.6 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) Hist_deacetyl PF00850.14 CEP09823.1 - 0.00074 18.9 0.1 0.00074 18.9 0.1 2.0 2 1 0 2 2 2 1 Histone deacetylase domain HTH_23 PF13384.1 CEP09825.1 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.5 CEP09825.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain LON PF02190.11 CEP09825.1 - 0.0014 18.3 0.0 0.0016 18.1 0.0 1.0 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain HTH_28 PF13518.1 CEP09825.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP09825.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.14 CEP09825.1 - 0.027 14.1 0.0 0.091 12.4 0.0 1.8 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_37 PF13744.1 CEP09825.1 - 0.091 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 CEP09825.1 - 0.092 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_hydro_35 PF01301.14 CEP09825.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HTH_20 PF12840.2 CEP09825.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 CEP09826.1 - 5.3e-17 61.9 0.0 7.7e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP09826.1 - 0.00059 19.0 0.0 0.00063 18.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease RNB PF00773.14 CEP09827.1 - 3.7e-83 279.4 0.1 7.2e-82 275.2 0.0 2.5 1 1 0 1 1 1 1 RNB domain HTH_29 PF13551.1 CEP09828.1 - 0.00051 20.1 0.0 0.00084 19.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP09828.1 - 0.0048 17.6 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 CEP09828.1 - 0.022 14.3 0.0 0.093 12.4 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.1 CEP09828.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.1 CEP09828.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Chromo PF00385.19 CEP09829.1 - 1.7e-10 40.4 0.8 3.1e-10 39.5 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP09829.1 - 0.00032 20.3 1.6 0.0019 17.8 0.2 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RuBisCO_small PF00101.15 CEP09829.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.4 1 1 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Phage_int_SAM_4 PF13495.1 CEP09831.1 - 0.0089 16.3 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain rve PF00665.21 CEP09833.1 - 1e-10 41.7 0.0 1.1e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DDE_2 PF02914.10 CEP09833.1 - 0.0033 16.9 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage Mu transposase MitMem_reg PF13012.1 CEP09834.1 - 0.039 14.0 0.8 0.11 12.5 0.5 2.0 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Transposase_31 PF04754.7 CEP09835.1 - 0.00015 21.2 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Putative transposase, YhgA-like PDDEXK_2 PF12784.2 CEP09835.1 - 0.02 14.0 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase DUF2887 PF11103.3 CEP09835.1 - 0.022 14.3 0.0 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2887) RVT_1 PF00078.22 CEP09836.1 - 0.0005 19.5 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP09838.1 - 2.8e-17 62.7 0.0 3.1e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CEP09840.1 - 9.2e-05 22.1 2.8 9.2e-05 22.1 1.9 1.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 CEP09840.1 - 0.14 11.6 0.5 0.14 11.6 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle rpo132 PF12415.3 CEP09842.1 - 0.034 13.1 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase Asp_protease_2 PF13650.1 CEP09843.1 - 7.2e-07 29.6 0.1 2e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 CEP09843.1 - 2.7e-05 24.1 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Adenylate_cycl PF01295.13 CEP09843.1 - 0.038 12.2 0.2 0.045 12.0 0.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I Alba PF01918.16 CEP09843.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 Alba FlaG PF03646.10 CEP09843.1 - 0.068 13.3 1.0 0.13 12.4 0.2 1.8 2 0 0 2 2 2 0 FlaG protein Asp_protease PF09668.5 CEP09843.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease SlyX PF04102.7 CEP09844.1 - 0.05 13.9 0.9 0.11 12.9 0.6 1.7 1 0 0 1 1 1 0 SlyX DUF3138 PF11336.3 CEP09844.1 - 0.082 11.0 0.5 0.095 10.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Lipid_DES PF08557.5 CEP09844.1 - 0.13 11.4 0.1 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) SspN PF08177.6 CEP09844.1 - 0.16 11.7 1.1 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Small acid-soluble spore protein N family zf-CHY PF05495.7 CEP09845.1 - 0.0013 18.8 3.8 0.22 11.7 0.2 2.4 2 0 0 2 2 2 2 CHY zinc finger Stc1 PF12898.2 CEP09845.1 - 0.014 15.4 1.1 0.19 11.8 0.1 2.4 2 0 0 2 2 2 0 Stc1 domain zf-C2HC_2 PF13913.1 CEP09845.1 - 0.042 13.5 5.4 0.099 12.3 0.5 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ADK_lid PF05191.9 CEP09845.1 - 0.05 13.2 0.1 0.89 9.2 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-H2C2_2 PF13465.1 CEP09845.1 - 0.065 13.5 2.3 1.6 9.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Cytochrome_C554 PF13435.1 CEP09845.1 - 0.089 12.8 3.6 3 7.8 0.3 2.3 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Zn_Tnp_IS1595 PF12760.2 CEP09845.1 - 0.096 12.5 3.0 0.31 10.8 0.6 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PHD PF00628.24 CEP09845.1 - 0.18 11.5 2.0 5.9 6.6 0.1 2.6 2 0 0 2 2 2 0 PHD-finger Elf1 PF05129.8 CEP09845.1 - 1.1 8.9 6.5 3.1 7.5 0.1 3.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Yippee-Mis18 PF03226.9 CEP09845.1 - 2.8 8.0 5.7 1.6 8.8 0.0 2.6 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.1 CEP09845.1 - 3.1 7.5 6.5 2.2 8.0 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain SlyX PF04102.7 CEP09846.1 - 0.013 15.8 2.6 0.014 15.7 1.8 1.1 1 0 0 1 1 1 0 SlyX FlxA PF14282.1 CEP09846.1 - 0.032 14.1 4.1 0.034 14.0 2.8 1.1 1 0 0 1 1 1 0 FlxA-like protein GAS PF13851.1 CEP09846.1 - 0.042 13.0 0.6 0.044 12.9 0.4 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4349 PF14257.1 CEP09846.1 - 0.049 12.8 0.7 0.054 12.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2802 PF10975.3 CEP09846.1 - 0.07 12.9 2.5 0.073 12.8 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) PilO PF04350.8 CEP09846.1 - 0.073 12.9 1.2 0.074 12.9 0.9 1.0 1 0 0 1 1 1 0 Pilus assembly protein, PilO ANTH PF07651.11 CEP09846.1 - 0.11 11.2 0.6 0.1 11.2 0.4 1.0 1 0 0 1 1 1 0 ANTH domain YbaB_DNA_bd PF02575.11 CEP09846.1 - 0.11 12.3 3.9 0.11 12.3 2.7 1.2 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family DUF3138 PF11336.3 CEP09846.1 - 0.12 10.5 3.1 0.11 10.6 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF972 PF06156.8 CEP09846.1 - 0.13 12.5 0.8 0.12 12.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Mito_fiss_reg PF05308.6 CEP09846.1 - 0.22 10.8 1.2 0.22 10.8 0.8 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator T2SJ PF11612.3 CEP09846.1 - 0.22 11.2 0.8 0.22 11.2 0.6 1.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J CENP-Q PF13094.1 CEP09848.1 - 0.0015 18.6 10.1 0.0021 18.1 7.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 CEP09848.1 - 0.0028 16.6 8.5 0.0032 16.4 5.9 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CEP09848.1 - 0.0043 16.6 5.9 0.0048 16.5 4.1 1.1 1 0 0 1 1 1 1 IncA protein APG6 PF04111.7 CEP09848.1 - 0.025 13.6 10.0 0.031 13.3 6.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Fmp27_WPPW PF10359.4 CEP09848.1 - 0.051 11.9 11.3 0.062 11.7 7.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc42p PF11544.3 CEP09848.1 - 0.063 13.2 21.0 0.11 12.4 11.6 2.8 2 1 0 2 2 2 0 Spindle pole body component Spc42p Mgr1 PF08602.5 CEP09848.1 - 0.11 11.5 9.5 0.12 11.4 6.6 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit V_ATPase_I PF01496.14 CEP09848.1 - 0.13 10.1 5.4 0.13 10.0 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.6 CEP09848.1 - 0.14 11.6 17.4 0.22 10.9 12.1 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF87 PF01935.12 CEP09848.1 - 0.16 11.7 5.7 0.2 11.4 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 FAM104 PF15434.1 CEP09848.1 - 0.19 11.9 7.8 1.2 9.3 1.6 2.2 1 1 1 2 2 2 0 Family 104 UPF0449 PF15136.1 CEP09848.1 - 0.41 10.8 5.8 1.1 9.4 4.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF3573 PF12097.3 CEP09848.1 - 0.61 8.6 13.2 0.77 8.3 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RNase_HII PF01351.13 CEP09848.1 - 1.1 8.9 7.1 1.4 8.5 5.0 1.1 1 0 0 1 1 1 0 Ribonuclease HII DUF3782 PF12644.2 CEP09848.1 - 2.6 7.9 5.2 4.2 7.2 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) TraG_N PF07916.6 CEP09848.1 - 3.1 6.1 10.0 1.4 7.3 5.5 1.4 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Guanylin PF02058.10 CEP09848.1 - 3.8 7.6 5.1 61 3.7 3.5 2.3 1 1 0 1 1 1 0 Guanylin precursor LMBR1 PF04791.11 CEP09848.1 - 9.1 4.7 6.5 11 4.5 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ank_2 PF12796.2 CEP09849.1 - 9.6e-12 45.0 0.0 1.7e-05 25.0 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP09849.1 - 9.2e-11 41.6 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP09849.1 - 2.4e-07 31.0 0.0 0.00092 19.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CEP09849.1 - 1.3e-06 27.9 0.0 9.7e-05 21.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 CEP09849.1 - 9.2e-05 22.3 0.0 0.0017 18.4 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_C65 PF10275.4 CEP09852.1 - 0.00075 18.9 0.8 0.0012 18.2 0.3 1.4 1 1 0 1 1 1 1 Peptidase C65 Otubain PIF1 PF05970.9 CEP09853.1 - 6.6e-57 193.1 0.0 7.5e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP09853.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEP09853.1 - 0.0035 17.0 0.1 0.024 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CEP09853.1 - 0.054 13.2 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 CEP09853.1 - 0.07 12.0 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4592 PF15262.1 CEP09856.1 - 0.052 14.0 2.2 0.061 13.8 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) ATP-synt_ab PF00006.20 CEP09859.1 - 2e-51 174.5 0.0 2.2e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 CEP09859.1 - 0.00062 19.5 0.0 0.00081 19.1 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CEP09859.1 - 0.0014 18.2 0.0 0.0021 17.7 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CEP09859.1 - 0.0045 16.9 0.1 0.009 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CEP09859.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CEP09859.1 - 0.01 14.7 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 CEP09859.1 - 0.011 15.4 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CEP09859.1 - 0.022 14.9 0.0 0.062 13.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CEP09859.1 - 0.037 14.1 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 CEP09859.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CEP09859.1 - 0.078 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CEP09859.1 - 0.086 11.7 0.0 0.53 9.1 0.1 1.8 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 CEP09859.1 - 0.091 11.8 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 CEP09859.1 - 0.11 12.4 0.1 2.3 8.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 CEP09859.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein SR-25 PF10500.4 CEP09863.1 - 2.4 7.5 16.7 0.092 12.2 7.1 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.14 CEP09864.1 - 1.1e-73 248.3 0.1 2.2e-73 247.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CEP09864.1 - 0.00019 21.5 0.0 0.00059 19.9 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEP09864.1 - 0.00099 19.0 0.0 0.0073 16.2 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.7 CEP09864.1 - 0.0017 18.0 0.3 0.0065 16.0 0.0 2.1 3 0 0 3 3 3 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 CEP09864.1 - 0.0043 17.0 0.1 0.013 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CEP09864.1 - 0.006 15.7 0.1 0.011 14.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CEP09864.1 - 0.013 13.9 0.1 0.029 12.8 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 CEP09864.1 - 0.021 13.9 1.2 0.083 11.9 0.9 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 CEP09864.1 - 0.041 12.7 1.8 0.16 10.8 1.3 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CEP09864.1 - 0.044 14.0 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 CEP09864.1 - 0.046 14.1 0.8 0.52 10.7 0.4 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CEP09864.1 - 0.046 13.3 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 CEP09864.1 - 0.076 11.9 0.3 0.13 11.1 0.2 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 CEP09864.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain B12D PF06522.6 CEP09865.1 - 4.5e-16 58.2 0.0 5.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit NUDIX PF00293.23 CEP09866.1 - 6.8e-16 58.1 0.0 1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.1 CEP09866.1 - 0.0021 17.5 0.0 0.0048 16.4 0.0 1.6 2 0 0 2 2 2 1 DBC1 PAP2 PF01569.16 CEP09867.1 - 3.8e-09 36.3 8.7 3.8e-09 36.3 6.1 1.8 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CEP09867.1 - 2.4e-06 27.2 4.6 4.5e-06 26.3 3.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily LTV PF04180.9 CEP09868.1 - 3.2e-52 178.4 51.9 2.2e-37 129.5 16.5 4.1 2 1 1 3 3 3 3 Low temperature viability protein DUF1743 PF08489.6 CEP09868.1 - 0.035 13.8 0.1 0.035 13.8 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1743) Arrestin_N PF00339.24 CEP09870.1 - 4.4e-14 52.5 0.1 6.8e-12 45.4 0.0 3.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP09870.1 - 2.7e-12 46.9 6.2 4.1e-08 33.4 2.3 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 CEP09870.1 - 0.00017 21.1 0.1 0.0004 19.9 0.1 1.7 1 1 0 1 1 1 1 Arrestin_N terminal like PRP1_N PF06424.7 CEP09870.1 - 0.047 14.0 2.0 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal SGT1 PF07093.6 CEP09871.1 - 9.8e-125 417.1 12.7 6.2e-124 414.5 8.8 1.8 1 1 0 1 1 1 1 SGT1 protein DUF3670 PF12419.3 CEP09871.1 - 0.0087 15.5 0.2 0.02 14.3 0.2 1.5 1 0 0 1 1 1 1 SNF2 Helicase protein SNARE PF05739.14 CEP09872.1 - 1.6e-14 53.3 2.6 6.7e-14 51.3 1.8 2.2 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CEP09872.1 - 1.2e-07 31.7 8.3 1.2e-07 31.7 5.8 3.4 3 1 0 3 3 3 1 Syntaxin Spectrin PF00435.16 CEP09872.1 - 0.01 16.1 3.5 0.01 16.1 2.4 3.1 3 1 0 3 3 3 0 Spectrin repeat DUF4183 PF13799.1 CEP09872.1 - 0.28 11.0 3.6 0.34 10.7 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4183) Lge1 PF11488.3 CEP09872.1 - 0.78 9.9 9.2 17 5.6 0.1 3.8 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 zf-C4H2 PF10146.4 CEP09872.1 - 2 8.3 16.8 0.54 10.2 2.6 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein IncA PF04156.9 CEP09872.1 - 3 7.3 17.1 5 6.6 2.9 2.4 2 0 0 2 2 2 0 IncA protein Adaptin_binding PF10199.4 CEP09872.1 - 3 8.1 14.6 1.3e+03 -0.5 10.1 2.2 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SAP PF02037.22 CEP09873.1 - 9.1e-11 41.0 0.2 1.7e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 SAP domain Methyltransf_11 PF08241.7 CEP09874.1 - 4.8e-13 49.4 0.0 1.4e-12 47.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP09874.1 - 3.2e-11 43.0 0.1 1.6e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP09874.1 - 8.3e-10 38.9 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP09874.1 - 5.5e-09 35.9 0.0 9.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP09874.1 - 2.4e-06 27.9 0.0 1.2e-05 25.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP09874.1 - 1.2e-05 24.5 0.2 0.00028 20.0 0.1 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CEP09874.1 - 5.7e-05 23.6 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CEP09874.1 - 5.8e-05 22.8 0.0 0.00032 20.4 0.0 2.1 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_2 PF00891.13 CEP09874.1 - 0.00021 20.5 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 CEP09874.1 - 0.00062 18.8 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 CEP09874.1 - 0.0034 17.4 0.0 0.0075 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 CEP09874.1 - 0.0042 15.4 0.0 0.0064 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 CEP09874.1 - 0.0046 16.3 0.0 0.024 14.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 CEP09874.1 - 0.01 14.9 0.1 0.028 13.4 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.7 CEP09874.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 CEP09874.1 - 0.017 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FtsJ PF01728.14 CEP09874.1 - 0.066 13.1 0.1 0.19 11.7 0.1 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Metallophos PF00149.23 CEP09875.1 - 7.8e-07 28.6 1.5 1.6e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP09875.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PNRC PF15365.1 CEP09876.1 - 4.1e-10 39.5 0.9 4.1e-10 39.5 0.6 4.5 4 3 0 4 4 4 1 Proline-rich nuclear receptor coactivator Macoilin PF09726.4 CEP09876.1 - 0.048 11.9 27.3 0.057 11.7 18.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 CEP09876.1 - 1.2 9.0 14.4 1.8 8.4 10.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PGA_cap PF09587.5 CEP09876.1 - 1.3 8.3 5.4 4.7 6.5 3.7 1.8 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap CAP_GLY PF01302.20 CEP09877.1 - 4.2e-23 80.8 0.5 6.4e-23 80.2 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain MS_channel PF00924.13 CEP09877.1 - 0.00078 18.8 0.1 0.00078 18.8 0.1 2.1 3 0 0 3 3 3 1 Mechanosensitive ion channel DUF2340 PF10209.4 CEP09877.1 - 0.45 10.6 10.0 0.049 13.7 2.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2340) Shugoshin_N PF07558.6 CEP09877.1 - 1.3 8.7 10.1 1.4 8.6 0.4 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Reo_sigmaC PF04582.7 CEP09877.1 - 9.5 5.2 7.1 23 4.0 4.5 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Acyl-CoA_dh_1 PF00441.19 CEP09878.1 - 4.8e-38 130.6 0.1 9.1e-38 129.7 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 CEP09878.1 - 1.2e-23 82.7 0.0 2.7e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 CEP09878.1 - 1.1e-19 69.6 0.1 2.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CEP09878.1 - 5.4e-16 59.1 0.0 1.1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEP09878.1 - 4.4e-05 23.7 0.0 8.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain VPS11_C PF12451.3 CEP09879.1 - 3.6e-14 52.3 1.0 1.2e-13 50.7 0.7 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 CEP09879.1 - 1.6e-13 50.4 14.2 3e-12 46.3 2.2 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps8 PF12816.2 CEP09879.1 - 0.01 15.1 2.1 0.56 9.4 0.5 2.5 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 Phage_GP20 PF06810.6 CEP09879.1 - 0.038 13.4 1.3 0.1 12.0 0.9 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 TPR_11 PF13414.1 CEP09879.1 - 0.081 12.5 0.3 1 9.0 0.0 2.6 2 0 0 2 2 2 0 TPR repeat zf-C3HC4_2 PF13923.1 CEP09879.1 - 0.12 12.4 5.2 0.22 11.5 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP09879.1 - 0.38 10.5 5.9 0.7 9.6 4.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CEP09879.1 - 0.63 9.9 6.3 1.3 8.8 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain WD40 PF00400.27 CEP09880.1 - 5e-18 64.2 0.6 7e-05 22.5 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat 7tm_3 PF00003.17 CEP09881.1 - 2.6e-26 92.4 26.5 4e-26 91.8 18.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 CEP09881.1 - 9.5e-18 64.0 0.3 6.2e-17 61.4 0.2 2.2 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 CEP09881.1 - 5.8e-10 39.0 1.6 1.3e-08 34.5 1.1 2.1 1 1 0 1 1 1 1 Periplasmic binding protein Glyco_tran_WecB PF03808.8 CEP09881.1 - 0.01 15.2 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Toprim_2 PF13155.1 CEP09881.1 - 0.1 12.9 0.0 0.69 10.2 0.0 2.4 2 0 0 2 2 2 0 Toprim-like PAP2_3 PF14378.1 CEP09881.1 - 1.4 8.4 12.9 0.078 12.4 2.8 2.5 2 0 0 2 2 2 0 PAP2 superfamily DIL PF01843.14 CEP09882.1 - 1e-21 76.7 7.0 1e-21 76.7 4.9 2.4 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.2 CEP09882.1 - 8e-17 61.3 0.2 2.4e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEP09882.1 - 6.5e-15 54.1 0.1 6.6e-07 28.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CEP09882.1 - 9.8e-15 54.2 0.2 2.1e-07 30.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP09882.1 - 2.5e-14 53.3 1.4 3.6e-07 30.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP09882.1 - 3e-08 33.1 1.0 0.01 15.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Diphthamide_syn PF01866.12 CEP09883.1 - 3e-114 381.4 0.0 3.8e-114 381.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SUR7 PF06687.7 CEP09883.1 - 3.1e-09 36.7 0.1 5.4e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 SUR7/PalI family Baculo_E56 PF04639.7 CEP09883.1 - 0.12 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope RVT_N PF13655.1 CEP09884.1 - 0.02 14.9 0.2 9.6 6.3 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase Nexin_C PF08628.7 CEP09884.1 - 0.054 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Sorting nexin C terminal HSP70 PF00012.15 CEP09885.1 - 0.00079 17.4 0.1 0.0011 16.9 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein ELMO_CED12 PF04727.8 CEP09887.1 - 8e-35 119.8 3.7 8.5e-35 119.7 0.1 2.5 3 0 0 3 3 3 1 ELMO/CED-12 family DUF3361 PF11841.3 CEP09887.1 - 2.3e-14 53.4 1.0 9.6e-14 51.4 0.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) Filament PF00038.16 CEP09888.1 - 0.0004 19.9 28.5 0.00062 19.3 9.8 12.5 1 1 11 12 12 12 7 Intermediate filament protein Reo_sigmaC PF04582.7 CEP09888.1 - 0.0041 16.3 132.6 0.0063 15.7 8.7 12.0 2 1 12 14 14 14 10 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 CEP09888.1 - 0.0079 16.3 5.5 0.0079 16.3 3.8 18.4 4 4 17 21 21 21 5 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 CEP09888.1 - 0.37 11.0 0.1 0.37 11.0 0.0 19.1 3 1 14 17 17 17 0 Nucleopolyhedrovirus P10 protein zf-RVT PF13966.1 CEP09889.1 - 0.00084 19.6 1.9 0.0017 18.6 1.3 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Phosphoprotein PF00922.12 CEP09892.1 - 0.035 13.3 0.7 0.04 13.1 0.5 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DNA_pol_A_exo1 PF01612.15 CEP09895.1 - 5.2e-11 42.3 0.1 2e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease DDE_3 PF13358.1 CEP09896.1 - 6.4e-15 55.1 0.0 3.4e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 CEP09898.1 - 6.4e-15 55.1 0.0 3.4e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Helitron_like_N PF14214.1 CEP09900.1 - 9.6e-20 71.0 0.0 1.1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 CEP09900.1 - 0.0074 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) DDE_3 PF13358.1 CEP09902.1 - 1.3e-06 28.2 0.0 1.6e-06 27.9 0.0 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease PIF1 PF05970.9 CEP09903.1 - 0.0068 15.4 0.0 0.017 14.0 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase HTH_29 PF13551.1 CEP09904.1 - 0.0005 20.1 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP09904.1 - 0.0053 17.5 0.1 0.054 14.3 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_AsnC-type PF13404.1 CEP09904.1 - 0.0092 15.5 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 CEP09904.1 - 0.03 13.7 1.2 0.069 12.5 0.9 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CobT PF06213.7 CEP09906.1 - 7 5.6 20.2 7.8 5.5 14.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FYDLN_acid PF09538.5 CEP09906.1 - 7.2 7.2 20.3 9.1 6.9 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Myc_N PF01056.13 CEP09906.1 - 9 5.3 13.2 13 4.8 9.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RR_TM4-6 PF06459.7 CEP09906.1 - 9.5 6.0 12.7 9.8 5.9 8.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Transposase_21 PF02992.9 CEP09908.1 - 0.00024 20.3 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 RVT_1 PF00078.22 CEP09910.1 - 2.5e-20 72.7 0.0 3.7e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BLOC1_2 PF10046.4 CEP09911.1 - 0.097 12.8 0.5 0.2 11.7 0.3 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YojJ PF10372.4 CEP09911.1 - 0.16 11.8 0.4 4.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Osmo_CC PF08946.5 CEP09911.1 - 4.7 7.3 6.4 12 6.0 1.2 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil F-box-like_2 PF13013.1 CEP09912.1 - 0.067 12.9 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 F-box-like domain rve PF00665.21 CEP09913.1 - 6e-19 68.3 0.0 1.2e-18 67.3 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_1_7 PF13843.1 CEP09914.1 - 0.07 12.1 0.0 0.072 12.1 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 DDE_Tnp_1_7 PF13843.1 CEP09915.1 - 2.4e-05 23.5 0.0 2.7e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 IL10 PF00726.12 CEP09915.1 - 0.0034 16.7 0.1 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Interleukin 10 E1-E2_ATPase PF00122.15 CEP09916.1 - 7.7e-50 169.0 4.9 7.7e-50 169.0 3.4 1.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP09916.1 - 1.1e-40 139.0 6.2 1.1e-40 139.0 4.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP09916.1 - 6.4e-32 111.7 0.0 1.4e-30 107.3 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP09916.1 - 5.5e-20 71.1 0.0 1e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP09916.1 - 1.8e-13 51.1 0.7 4e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP09916.1 - 1.2e-07 31.1 0.0 1.2e-07 31.1 0.0 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP09916.1 - 0.00011 21.9 0.2 0.0002 21.0 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.2 CEP09916.1 - 0.032 14.1 0.7 0.032 14.1 0.5 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) DUF2975 PF11188.3 CEP09916.1 - 0.79 9.4 17.0 0.12 12.0 1.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) UpxZ PF06603.6 CEP09917.1 - 0.0031 17.5 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 UpxZ family of transcription anti-terminator antagonists SPT2 PF08243.6 CEP09918.1 - 5.6e-18 65.3 18.4 5.6e-18 65.3 12.8 4.2 3 1 1 4 4 4 1 SPT2 chromatin protein ABC_tran PF00005.22 CEP09919.1 - 5.5e-33 114.1 1.2 3.7e-18 66.1 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CEP09919.1 - 1.5e-12 48.1 0.0 0.004 17.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 CEP09919.1 - 1.2e-08 34.4 0.0 0.063 12.5 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CEP09919.1 - 1.9e-08 35.1 0.0 0.0011 19.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CEP09919.1 - 5.7e-08 33.0 0.2 0.034 14.3 0.0 4.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CEP09919.1 - 5.9e-08 32.1 0.0 0.009 15.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CEP09919.1 - 2.1e-07 30.2 0.0 0.0011 18.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 CEP09919.1 - 3.5e-07 30.3 0.0 0.035 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CEP09919.1 - 3.7e-07 30.3 0.1 0.014 15.5 0.0 3.6 4 0 0 4 4 3 2 AAA domain Miro PF08477.8 CEP09919.1 - 8.4e-07 29.5 0.0 0.09 13.2 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein MMR_HSR1 PF01926.18 CEP09919.1 - 2.2e-06 27.6 0.0 0.015 15.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 CEP09919.1 - 4e-06 26.1 0.0 0.67 8.9 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.7 CEP09919.1 - 7e-06 25.7 0.0 0.054 13.1 0.0 3.2 3 0 0 3 3 3 2 NACHT domain AAA_23 PF13476.1 CEP09919.1 - 8.7e-06 26.1 3.5 0.072 13.4 0.5 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CEP09919.1 - 1.3e-05 25.3 0.0 0.22 11.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 CEP09919.1 - 2e-05 23.5 0.0 0.1 11.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 CEP09919.1 - 2.2e-05 24.1 0.0 0.14 11.8 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CEP09919.1 - 3.7e-05 23.7 0.5 0.07 13.1 0.0 3.1 4 0 0 4 4 3 1 AAA ATPase domain AAA_18 PF13238.1 CEP09919.1 - 4.5e-05 23.7 0.1 0.12 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CEP09919.1 - 8e-05 22.5 0.0 0.48 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain HEAT PF02985.17 CEP09919.1 - 9.2e-05 22.2 1.7 2.6 8.3 0.0 4.7 4 0 0 4 4 3 1 HEAT repeat AAA_14 PF13173.1 CEP09919.1 - 0.00013 21.8 0.0 0.13 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Chromo PF00385.19 CEP09919.1 - 0.00015 21.3 1.5 0.00044 19.8 0.2 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_10 PF12846.2 CEP09919.1 - 0.00016 21.2 0.0 0.38 10.1 0.0 2.7 3 0 0 3 3 3 2 AAA-like domain DUF815 PF05673.8 CEP09919.1 - 0.00018 20.5 0.0 0.41 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) PduV-EutP PF10662.4 CEP09919.1 - 0.00029 20.3 0.0 0.48 9.8 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 CEP09919.1 - 0.00042 19.8 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 CEP09919.1 - 0.00057 19.7 0.4 0.23 11.2 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 CEP09919.1 - 0.0012 18.5 0.0 0.69 9.5 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase Vac14_Fab1_bd PF12755.2 CEP09919.1 - 0.002 18.4 0.3 0.69 10.3 0.0 3.4 3 1 2 5 5 3 1 Vacuolar 14 Fab1-binding region Dynamin_N PF00350.18 CEP09919.1 - 0.0022 17.8 0.0 0.39 10.5 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.1 CEP09919.1 - 0.0068 16.0 0.1 1.4 8.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_13 PF13166.1 CEP09919.1 - 0.0081 14.6 0.0 2.8 6.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEP09919.1 - 0.0082 15.5 0.0 4.6 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain MutS_V PF00488.16 CEP09919.1 - 0.011 15.1 0.1 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 MutS domain V Zeta_toxin PF06414.7 CEP09919.1 - 0.012 14.7 0.0 2.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.13 CEP09919.1 - 0.017 14.6 0.0 0.38 10.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CEP09919.1 - 0.018 13.9 0.1 0.99 8.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 CEP09919.1 - 0.024 14.1 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 CEP09919.1 - 0.033 12.8 0.1 3.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF1546 PF07571.8 CEP09919.1 - 0.034 14.2 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1546) NTPase_1 PF03266.10 CEP09919.1 - 0.035 13.8 0.1 5.1 6.7 0.1 2.8 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 CEP09919.1 - 0.044 13.5 0.4 14 5.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF4484 PF14831.1 CEP09920.1 - 0.067 13.2 0.1 0.081 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) LTV PF04180.9 CEP09922.1 - 0.88 9.0 10.4 1.1 8.7 7.2 1.1 1 0 0 1 1 1 0 Low temperature viability protein PIF1 PF05970.9 CEP09923.1 - 1.9e-26 92.9 0.0 2.9e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP09923.1 - 0.00013 19.9 0.0 0.00019 19.3 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP09923.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain FTCD_C PF04961.7 CEP09927.1 - 0.0043 16.4 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Gar1 PF04410.9 CEP09928.1 - 8e-40 135.8 1.9 8e-40 135.8 1.3 2.7 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Fungal_trans_2 PF11951.3 CEP09928.1 - 0.091 11.3 2.3 0.075 11.6 0.4 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Cwf_Cwc_15 PF04889.7 CEP09928.1 - 2.7 7.6 14.8 1.7 8.3 0.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.13 CEP09928.1 - 2.8 7.0 8.0 0.62 9.1 0.2 2.1 2 0 0 2 2 2 0 Myc amino-terminal region AAA_2 PF07724.9 CEP09929.1 - 8e-41 139.7 0.2 1.8e-39 135.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CEP09929.1 - 1.4e-15 57.6 0.1 4.2e-15 56.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CEP09929.1 - 2.9e-09 36.6 0.3 2.9e-09 36.6 0.2 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CEP09929.1 - 2.5e-07 30.5 0.0 7.1e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CEP09929.1 - 2.2e-06 26.9 3.3 0.00057 19.1 0.1 3.8 2 2 2 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 CEP09929.1 - 7.1e-06 26.1 0.2 0.00064 19.8 0.1 2.9 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CEP09929.1 - 5.2e-05 22.7 0.0 0.018 14.5 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CEP09929.1 - 0.00016 21.1 0.0 0.0005 19.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CEP09929.1 - 0.00026 20.8 0.7 0.0046 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP09929.1 - 0.00034 21.4 0.0 0.00085 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CEP09929.1 - 0.00037 20.4 0.0 0.0012 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEP09929.1 - 0.00045 19.3 0.2 0.0069 15.4 0.1 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 CEP09929.1 - 0.0013 18.7 0.0 0.0041 17.1 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 CEP09929.1 - 0.0013 18.9 0.8 0.0088 16.3 0.0 2.6 3 0 0 3 3 2 1 ABC transporter AAA_16 PF13191.1 CEP09929.1 - 0.0016 18.4 2.5 0.0027 17.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 CEP09929.1 - 0.0018 17.2 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 CEP09929.1 - 0.0029 16.8 0.0 0.008 15.4 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 CEP09929.1 - 0.0078 16.0 0.3 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 CEP09929.1 - 0.0097 15.5 0.0 0.05 13.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 CEP09929.1 - 0.017 14.8 0.2 0.053 13.2 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain AAA_18 PF13238.1 CEP09929.1 - 0.024 14.9 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CEP09929.1 - 0.033 13.7 1.0 0.055 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CEP09929.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 CEP09929.1 - 0.047 13.6 0.6 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 CEP09929.1 - 0.056 12.2 0.5 0.29 9.8 0.1 2.2 2 1 0 2 2 2 0 MCM2/3/5 family UPF0079 PF02367.12 CEP09929.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 CEP09929.1 - 0.13 11.7 0.1 0.13 11.7 0.0 2.1 2 1 0 3 3 2 0 DEAD/DEAH box helicase AAA_23 PF13476.1 CEP09929.1 - 2 8.7 0.0 2 8.7 0.0 2.9 1 1 1 2 2 1 0 AAA domain G-alpha PF00503.15 CEP09929.1 - 3.3 6.3 10.5 6.2 5.4 7.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit Swi3 PF07962.7 CEP09930.1 - 2.2e-08 33.6 0.0 2.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NCD2 PF04905.8 CEP09931.1 - 0.13 12.0 0.3 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) Ribosomal_L37ae PF01780.14 CEP09932.1 - 1e-40 137.4 11.3 1.1e-40 137.3 7.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 CEP09932.1 - 0.00066 19.4 2.3 0.00096 18.9 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CEP09932.1 - 0.0012 18.1 3.3 0.55 9.7 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 CEP09932.1 - 0.016 14.8 2.6 0.3 10.7 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif OrfB_Zn_ribbon PF07282.6 CEP09932.1 - 0.075 12.6 1.5 0.11 12.2 1.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.1 CEP09932.1 - 0.092 13.0 2.0 1.7 9.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 CEP09932.1 - 0.15 12.0 2.0 0.78 9.7 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 CEP09932.1 - 0.22 11.0 0.9 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Elf1 PF05129.8 CEP09932.1 - 0.23 11.1 3.0 0.41 10.3 2.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 CEP09932.1 - 0.26 11.0 6.2 0.25 11.1 0.6 2.3 1 1 1 2 2 2 0 BED zinc finger C1_1 PF00130.17 CEP09932.1 - 0.34 10.6 2.9 0.49 10.1 2.0 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CarbpepA_inh PF02977.10 CEP09932.1 - 1.7 8.2 5.4 8.5 6.0 3.7 2.0 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 CEP09932.1 - 2.3 8.7 4.5 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_60s PF00428.14 CEP09933.1 - 1.5e-22 79.7 7.7 1.8e-22 79.4 5.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein FA_hydroxylase PF04116.8 CEP09934.1 - 1.3e-13 51.3 9.3 1.3e-13 51.3 6.4 3.1 2 2 1 3 3 3 1 Fatty acid hydroxylase superfamily 5_nucleotid_C PF02872.13 CEP09935.1 - 3.4e-34 118.0 0.0 9.8e-34 116.5 0.0 1.8 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CEP09935.1 - 0.0045 16.4 0.2 0.012 15.0 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HSP20 PF00011.16 CEP09936.1 - 5.3e-18 64.7 0.2 4.1e-11 42.6 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family tRNA_synt_1c_R2 PF04557.10 CEP09936.1 - 0.14 12.9 1.7 5.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Thiolase_C PF02803.13 CEP09937.1 - 1.3e-12 47.2 0.1 4.7e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CEP09937.1 - 4.2e-09 35.7 0.0 1.4e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 CEP09937.1 - 1.9e-05 24.4 0.1 0.015 15.1 0.0 3.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 CEP09937.1 - 0.00032 20.2 4.6 0.0042 16.5 1.0 2.6 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CEP09937.1 - 0.00069 19.2 1.0 0.015 14.9 0.3 2.8 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 CEP09937.1 - 0.011 14.1 0.4 0.71 8.2 0.1 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) HMG_CoA_synt_N PF01154.12 CEP09937.1 - 0.056 13.0 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal CHAP PF05257.11 CEP09937.1 - 0.11 12.1 1.5 0.53 9.9 0.2 2.6 3 0 0 3 3 3 0 CHAP domain MsyB PF13984.1 CEP09939.1 - 0.027 14.5 0.0 0.038 14.0 0.0 1.1 1 0 0 1 1 1 0 MsyB protein Spectrin PF00435.16 CEP09940.1 - 0.056 13.7 3.1 0.074 13.3 0.2 2.1 2 0 0 2 2 2 0 Spectrin repeat RseA_C PF03873.8 CEP09940.1 - 0.21 11.4 1.9 0.72 9.7 0.1 2.6 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain DUF1640 PF07798.6 CEP09940.1 - 1.1 9.2 8.7 0.5 10.3 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) BCL_N PF04714.8 CEP09941.1 - 0.08 12.5 0.3 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 BCL7, N-terminal conserver region eIF2A PF08662.6 CEP09942.1 - 8.8e-08 32.0 0.8 0.0024 17.6 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CEP09942.1 - 2e-07 30.5 0.3 1.9 8.4 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.7 CEP09942.1 - 0.00023 20.7 0.8 0.46 10.2 0.0 3.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat IKI3 PF04762.7 CEP09942.1 - 0.0042 14.9 0.3 0.026 12.3 0.1 2.1 1 1 0 1 1 1 1 IKI3 family Apc4_WD40 PF12894.2 CEP09942.1 - 0.068 12.6 0.0 0.74 9.3 0.0 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.1 CEP09943.1 - 2.3e-14 52.9 11.8 3.8e-14 52.2 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP09943.1 - 8.3e-10 38.6 8.9 1.6e-09 37.7 6.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CEP09943.1 - 9.5e-07 28.7 10.7 1.5e-06 28.0 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP09943.1 - 4.7e-06 26.1 9.2 7.9e-06 25.4 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP09943.1 - 8.6e-06 25.3 8.9 1.4e-05 24.7 6.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP09943.1 - 1e-05 25.0 8.6 1.6e-05 24.4 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CEP09943.1 - 0.00084 18.8 4.6 0.0017 17.8 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CEP09943.1 - 0.0061 16.2 2.5 0.0061 16.2 1.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CEP09943.1 - 0.009 15.8 8.6 0.043 13.6 6.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CEP09943.1 - 0.035 13.9 7.8 0.068 13.0 5.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 CEP09943.1 - 2.2 8.3 10.6 3.2 7.8 6.8 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 CEP09943.1 - 3.4 7.3 6.6 6.1 6.5 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 CEP09943.1 - 5.5 6.8 9.6 12 5.6 6.7 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Aminotran_1_2 PF00155.16 CEP09944.1 - 2.8e-41 141.6 0.0 4.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEP09944.1 - 0.0023 17.1 1.0 0.0038 16.4 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase RVT_1 PF00078.22 CEP09945.1 - 4.8e-09 35.8 0.0 7.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4261 PF14080.1 CEP09946.1 - 0.033 13.9 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) PS_Dcarbxylase PF02666.10 CEP09947.1 - 2.3e-47 160.9 0.2 1.9e-46 157.9 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase UPF0014 PF03649.8 CEP09949.1 - 5.6e-43 146.8 17.4 7.6e-43 146.4 12.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 CEP09949.1 - 0.0046 16.7 7.0 0.0046 16.7 4.8 3.5 1 1 2 3 3 3 2 FtsX-like permease family KH_1 PF00013.24 CEP09950.1 - 8.7e-48 159.8 8.3 2e-16 59.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CEP09950.1 - 4e-35 118.8 10.8 7.5e-14 51.0 0.5 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CEP09950.1 - 2.4e-15 55.8 3.4 0.0009 18.7 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CEP09950.1 - 1.5e-09 37.3 3.0 0.026 14.1 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CEP09950.1 - 0.00044 20.0 0.5 0.51 10.1 0.0 3.4 3 0 0 3 3 3 1 NusA-like KH domain Methyltransf_26 PF13659.1 CEP09951.1 - 2.3e-14 53.4 0.0 4.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP09951.1 - 1.3e-13 50.8 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP09951.1 - 9e-12 44.6 0.0 1.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CEP09951.1 - 9.3e-11 42.3 0.0 1.7e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP09951.1 - 1e-08 35.4 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 CEP09951.1 - 6.3e-07 28.7 0.0 8.9e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.13 CEP09951.1 - 2.2e-06 27.3 0.0 5.1e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 CEP09951.1 - 2.4e-05 24.7 0.0 4.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP09951.1 - 3.4e-05 23.0 0.0 6.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CEP09951.1 - 4.7e-05 23.7 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CEP09951.1 - 0.00012 21.3 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CEP09951.1 - 0.00033 20.3 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 CEP09951.1 - 0.00072 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CEP09951.1 - 0.0016 18.1 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CEP09951.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_10 PF05971.7 CEP09951.1 - 0.0043 16.2 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) PCMT PF01135.14 CEP09951.1 - 0.0078 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_20 PF12147.3 CEP09951.1 - 0.015 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FmrO PF07091.6 CEP09951.1 - 0.025 13.5 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_3 PF01596.12 CEP09951.1 - 0.078 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 CEP09951.1 - 0.095 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase ApoB100_C PF12491.3 CEP09953.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal Exo_endo_phos_2 PF14529.1 CEP09954.1 - 5.2e-09 35.7 0.1 1.1e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP09954.1 - 0.0026 17.7 1.8 0.0032 17.4 0.5 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Herpes_env PF01673.13 CEP09955.1 - 0.0091 14.6 0.0 0.01 14.4 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus putative major envelope glycoprotein PRESAN PF09687.5 CEP09955.1 - 0.29 11.1 3.0 0.12 12.4 0.4 1.5 2 0 0 2 2 2 0 Plasmodium RESA N-terminal DUF4611 PF15387.1 CEP09957.1 - 0.0046 17.0 2.7 0.0096 16.0 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Sec5 PF15469.1 CEP09957.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 FAD_binding_8 PF08022.7 CEP09958.1 - 1e-09 38.2 0.1 0.0003 20.6 0.0 2.2 2 0 0 2 2 2 2 FAD-binding domain FAD_binding_6 PF00970.19 CEP09958.1 - 0.022 14.8 0.0 4.4 7.4 0.0 2.4 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain DUF3277 PF11681.3 CEP09958.1 - 0.082 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) RVT_1 PF00078.22 CEP09959.1 - 5e-07 29.2 0.1 1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RHH_3 PF12651.2 CEP09959.1 - 0.089 12.5 0.3 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain zf-RVT PF13966.1 CEP09960.1 - 1.3e-07 31.8 0.1 2.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C2H2 PF00096.21 CEP09963.1 - 0.21 11.9 1.2 0.36 11.2 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3419 PF11899.3 CEP09965.1 - 1.2e-13 50.6 0.0 2.1e-07 29.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3419) DUF2537 PF10801.3 CEP09965.1 - 0.029 14.4 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) SH3_9 PF14604.1 CEP09966.1 - 1.4e-13 50.1 0.0 1.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP09966.1 - 3e-13 48.9 0.0 4.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP09966.1 - 1.3e-07 31.0 0.0 1.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CEP09966.1 - 0.00087 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain HTH_28 PF13518.1 CEP09969.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 CEP09973.1 - 3.5e-34 117.6 0.2 1.5e-33 115.6 0.0 2.2 2 2 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP09973.1 - 0.00017 20.7 1.1 0.00043 19.4 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 CEP09973.1 - 0.034 14.2 0.1 0.36 10.9 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain Cu_amine_oxidN2 PF02727.11 CEP09976.1 - 9.8e-05 22.3 0.0 0.00013 21.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF4302 PF14135.1 CEP09978.1 - 0.006 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4302) CDC37_N PF03234.9 CEP09978.1 - 0.061 13.6 1.7 1 9.6 0.2 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF87 PF01935.12 CEP09979.1 - 0.33 10.7 3.5 0.42 10.3 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 SSPI PF14098.1 CEP09979.1 - 1.5 8.8 8.6 10 6.1 0.5 3.2 2 1 1 3 3 3 0 Small, acid-soluble spore protein I ATAD4 PF15321.1 CEP09979.1 - 2.6 9.0 6.0 4.9 8.2 4.1 1.6 1 1 0 1 1 1 0 ATPase family AAA domain containing 4 dsDNA_bind PF01984.15 CEP09979.1 - 4.6 7.2 20.9 0.04 13.9 7.2 2.3 3 0 0 3 3 3 0 Double-stranded DNA-binding domain FAM104 PF15434.1 CEP09981.1 - 0.34 11.1 7.8 0.38 10.9 5.4 1.1 1 0 0 1 1 1 0 Family 104 zf-CCHC PF00098.18 CEP09982.1 - 2.5e-05 23.9 2.3 4.1e-05 23.2 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEP09982.1 - 6.9e-05 22.8 0.5 0.00015 21.8 0.2 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 CEP09982.1 - 0.068 12.9 1.3 0.16 11.7 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Phage_C PF12025.3 CEP09982.1 - 0.48 10.4 2.5 0.79 9.7 0.5 2.3 1 1 0 2 2 2 0 Phage protein C PIF1 PF05970.9 CEP09984.1 - 4.7e-11 42.2 0.4 1e-10 41.0 0.3 1.5 1 1 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 CEP09984.1 - 0.00028 20.9 0.0 0.0006 19.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEP09984.1 - 0.004 14.9 0.0 0.0068 14.2 0.0 1.3 1 0 0 1 1 1 1 Helicase DUF2824 PF11039.3 CEP09984.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) Elf1 PF05129.8 CEP09985.1 - 0.017 14.8 0.9 0.017 14.8 0.6 2.9 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 CEP09985.1 - 0.97 9.7 4.8 0.77 10.1 1.4 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-Di19 PF05605.7 CEP09985.1 - 1.2 9.3 5.8 1.3 9.1 1.4 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CCHC PF00098.18 CEP09987.1 - 0.00095 18.9 1.4 0.00095 18.9 1.0 1.8 2 0 0 2 2 2 1 Zinc knuckle Spexin PF15171.1 CEP09987.1 - 0.037 14.0 0.2 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin zf-CCHC_2 PF13696.1 CEP09987.1 - 0.12 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle ANF_receptor PF01094.23 CEP09988.1 - 1.5e-34 119.3 1.3 3.8e-34 118.0 0.9 1.7 1 0 0 1 1 1 1 Receptor family ligand binding region DIL PF01843.14 CEP09988.1 - 5.7e-22 77.5 1.5 5.7e-22 77.5 1.1 2.8 3 0 0 3 3 3 1 DIL domain Ank_2 PF12796.2 CEP09988.1 - 1.2e-18 67.2 0.0 3.4e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) 7tm_3 PF00003.17 CEP09988.1 - 5e-18 65.3 14.3 1.3e-17 63.9 9.9 1.6 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.1 CEP09988.1 - 1.1e-16 61.1 1.2 1.1e-16 61.1 0.8 1.5 2 0 0 2 2 2 1 Periplasmic binding protein Ank PF00023.25 CEP09988.1 - 2.4e-16 58.6 0.0 5.1e-08 32.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CEP09988.1 - 3.9e-10 39.6 0.0 6.8e-07 29.3 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP09988.1 - 1.1e-08 34.4 0.0 0.015 15.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CEP09988.1 - 1.8e-07 31.4 0.0 7e-06 26.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Suf PF05843.9 CEP09988.1 - 0.0004 20.2 6.1 0.0004 20.2 4.2 3.2 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) COX15-CtaA PF02628.10 CEP09989.1 - 1.9e-86 289.6 1.2 2.3e-86 289.3 0.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RrnaAD PF00398.15 CEP09990.1 - 4.5e-61 206.1 0.0 5.9e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CEP09990.1 - 2.6e-11 43.5 0.0 4.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP09990.1 - 1.6e-05 25.4 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP09990.1 - 0.00018 20.9 0.1 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 CEP09990.1 - 0.00037 20.0 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CEP09990.1 - 0.00094 18.7 0.1 0.0073 15.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP09990.1 - 0.0037 17.7 0.0 0.0084 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP09990.1 - 0.0061 16.3 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEP09990.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_28 PF02636.12 CEP09990.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 CEP09990.1 - 0.016 14.2 0.0 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.13 CEP09990.1 - 0.02 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase NodS PF05401.6 CEP09990.1 - 0.035 13.4 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 CEP09990.1 - 0.054 12.3 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase GCV_H PF01597.14 CEP09991.1 - 0.029 14.0 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein IIGP PF05049.8 CEP09992.1 - 4.4e-29 101.4 0.0 6e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 CEP09992.1 - 1.2e-08 34.8 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CEP09992.1 - 0.00012 22.3 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter FeoB_N PF02421.13 CEP09992.1 - 0.0002 20.6 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 CEP09992.1 - 0.00029 20.0 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CEP09992.1 - 0.00041 20.8 0.0 0.0013 19.1 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CEP09992.1 - 0.0031 17.0 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 CEP09992.1 - 0.0035 17.1 0.4 0.14 11.9 0.2 2.2 1 1 1 2 2 2 1 Dynamin family AAA_29 PF13555.1 CEP09992.1 - 0.008 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.11 CEP09992.1 - 0.0099 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_17 PF13207.1 CEP09992.1 - 0.018 15.8 0.3 0.029 15.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEP09992.1 - 0.046 13.6 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 CEP09992.1 - 0.048 12.4 0.0 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Ras PF00071.17 CEP09992.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras family MobB PF03205.9 CEP09992.1 - 0.053 13.2 0.2 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 CEP09992.1 - 0.059 12.7 0.5 8.4 5.7 0.0 2.6 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain SMC_N PF02463.14 CEP09992.1 - 0.078 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CEP09992.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CEP09992.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CEP09992.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 CEP09992.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CsbD PF05532.7 CEP09993.1 - 4.6e-15 55.0 12.8 3.6e-12 45.7 0.4 2.0 1 1 1 2 2 2 2 CsbD-like Birna_VP4 PF01768.11 CEP09993.1 - 0.085 11.9 0.5 0.14 11.2 0.2 1.4 1 1 0 1 1 1 0 Birnavirus VP4 protein HSP9_HSP12 PF04119.7 CEP09993.1 - 0.12 12.4 0.6 0.68 10.0 0.1 2.3 1 1 1 2 2 2 0 Heat shock protein 9/12 Inhibitor_Mig-6 PF11555.3 CEP09994.1 - 0.023 15.0 0.2 0.069 13.5 0.1 1.8 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 BAMBI PF06211.7 CEP09994.1 - 1.3 9.0 5.8 0.22 11.5 0.8 2.0 2 0 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain zf-RING_2 PF13639.1 CEP09995.1 - 4.8e-15 55.1 5.1 8.4e-15 54.3 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 CEP09995.1 - 1.3e-10 40.8 0.0 2.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 CEP09995.1 - 2.5e-10 40.3 1.2 5.2e-10 39.2 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP09995.1 - 1.8e-08 33.8 5.3 3e-08 33.1 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP09995.1 - 3.2e-08 33.1 2.1 5.3e-08 32.3 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP09995.1 - 1.1e-07 31.7 4.9 1.9e-07 30.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP09995.1 - 3e-07 30.0 4.1 4.7e-07 29.4 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CEP09995.1 - 0.00019 21.2 3.6 0.00075 19.2 2.5 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CEP09995.1 - 0.00099 18.6 3.6 0.0018 17.8 2.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.2 CEP09995.1 - 0.023 14.7 3.3 0.052 13.5 2.3 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 CEP09995.1 - 0.031 14.2 5.7 0.36 10.8 4.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 CEP09995.1 - 0.093 12.4 4.1 0.17 11.6 2.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 CEP09995.1 - 0.38 10.8 4.0 0.7 9.9 2.8 1.5 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.20 CEP09996.1 - 4.9e-62 209.4 0.0 6.6e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP09996.1 - 4.2e-34 117.8 0.0 8.6e-33 113.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP09996.1 - 7.9e-11 41.4 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP09996.1 - 0.022 14.5 0.2 0.43 10.2 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Transket_pyr PF02779.19 CEP09997.1 - 2.1e-61 206.5 0.0 3.3e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CEP09997.1 - 1e-59 201.7 0.0 1.4e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component NSP2-B_epitope PF14757.1 CEP09997.1 - 0.046 13.2 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Toxin_29 PF08116.6 CEP09998.1 - 0.0031 17.2 1.3 0.0074 16.0 0.9 1.6 1 0 0 1 1 1 1 PhTx neurotoxin family DUF2615 PF11027.3 CEP09998.1 - 0.0058 16.5 0.1 0.016 15.1 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2615) DUF2561 PF10812.3 CEP09998.1 - 0.011 15.3 0.1 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF1510 PF07423.6 CEP09998.1 - 0.014 14.7 1.0 0.019 14.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TMEM51 PF15345.1 CEP09998.1 - 0.015 14.9 3.2 0.022 14.4 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 UPF0506 PF11703.3 CEP09998.1 - 0.018 14.9 7.1 0.035 14.0 4.9 1.4 1 0 0 1 1 1 0 UPF0506 EphA2_TM PF14575.1 CEP09998.1 - 0.021 15.1 0.1 0.021 15.1 0.0 1.9 3 0 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain 7tm_1 PF00001.16 CEP09998.1 - 0.076 12.1 0.1 0.091 11.8 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CRPA PF05745.6 CEP09998.1 - 0.078 12.7 0.7 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Neur_chan_memb PF02932.11 CEP09998.1 - 0.19 11.5 2.3 0.13 12.1 0.4 1.5 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EB PF01683.13 CEP09998.1 - 0.22 11.5 9.3 0.5 10.4 6.4 1.6 1 1 0 1 1 1 0 EB module CcmD PF04995.9 CEP09998.1 - 0.23 11.2 0.9 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2207 PF09972.4 CEP09998.1 - 0.43 9.1 3.5 3.1 6.2 0.5 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) MIS13 PF08202.6 CEP10000.1 - 1.7e-07 30.6 2.9 0.0033 16.5 0.0 2.6 1 1 2 3 3 3 2 Mis12-Mtw1 protein family Nop14 PF04147.7 CEP10001.1 - 0.049 11.5 3.6 0.053 11.4 2.5 1.0 1 0 0 1 1 1 0 Nop14-like family Aa_trans PF01490.13 CEP10002.1 - 7.4e-48 163.0 17.5 9.2e-48 162.7 12.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CEP10002.1 - 3.4e-05 22.8 8.7 3.4e-05 22.8 6.0 1.8 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family HEAT PF02985.17 CEP10003.1 - 2.2e-14 52.1 11.6 0.059 13.4 0.1 11.6 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 CEP10003.1 - 9.1e-13 48.3 20.5 0.25 11.6 0.4 9.8 8 3 2 11 11 11 6 HEAT repeats Cnd1 PF12717.2 CEP10003.1 - 0.00068 19.5 1.7 1.5 8.6 0.0 6.1 7 1 1 8 8 8 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CEP10003.1 - 0.013 15.8 0.0 9.2 6.7 0.0 4.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CEP10003.1 - 0.015 15.7 12.1 15 6.2 0.3 7.5 7 1 1 8 8 8 0 HEAT-like repeat Cohesin_HEAT PF12765.2 CEP10003.1 - 0.24 11.3 2.7 24 5.0 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion GATA PF00320.22 CEP10004.1 - 0.59 9.5 22.9 0.21 10.9 6.4 3.3 2 1 0 2 2 2 0 GATA zinc finger DZR PF12773.2 CEP10004.1 - 2.1 8.2 10.2 1 9.2 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF3425 PF11905.3 CEP10005.1 - 1.9e-11 44.0 6.4 1.9e-11 44.0 4.4 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CEP10005.1 - 7.4e-06 25.8 9.5 7.4e-06 25.8 6.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 CEP10005.1 - 0.054 13.0 0.4 0.17 11.4 0.3 1.8 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain HTH_Tnp_Tc5 PF03221.11 CEP10006.1 - 0.0064 16.2 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3425 PF11905.3 CEP10008.1 - 3.9e-10 39.7 0.5 5.8e-08 32.7 0.3 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CEP10008.1 - 1.7 8.6 20.1 0.14 12.1 9.7 2.4 2 1 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 CEP10008.1 - 2.6 7.9 16.4 16 5.3 11.4 2.4 1 1 0 1 1 1 0 Basic region leucine zipper F-box-like PF12937.2 CEP10010.1 - 4e-05 23.2 0.6 7.1e-05 22.4 0.4 1.4 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.12 CEP10010.1 - 0.00057 19.5 0.2 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEP10010.1 - 0.0014 18.1 0.0 0.0033 16.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.28 CEP10010.1 - 0.0086 15.7 0.5 0.019 14.5 0.4 1.6 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 CEP10010.1 - 0.069 12.8 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 TPR repeat YL1 PF05764.8 CEP10011.1 - 3.6e-32 111.8 23.9 3.6e-32 111.8 16.6 2.1 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 CEP10011.1 - 2e-12 46.4 0.5 3.5e-12 45.6 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DPBB_1 PF03330.13 CEP10012.1 - 2.2e-05 24.3 3.4 3.1e-05 23.8 0.2 2.7 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP10012.1 - 0.0036 16.9 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 Barwin family Endostatin PF06482.6 CEP10012.1 - 0.0043 16.4 0.1 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin GSH_synth_ATP PF03917.12 CEP10012.1 - 0.0093 14.5 0.1 0.011 14.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain Rtf2 PF04641.7 CEP10012.1 - 0.021 14.0 4.5 0.024 13.8 3.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger SR-25 PF10500.4 CEP10012.1 - 0.029 13.8 14.8 0.039 13.4 10.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RHINO PF15319.1 CEP10012.1 - 0.033 14.0 3.5 0.048 13.4 2.4 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein DUF755 PF05501.6 CEP10012.1 - 0.035 14.1 21.4 0.048 13.7 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BLVR PF06375.6 CEP10012.1 - 0.053 13.3 10.1 0.092 12.5 7.0 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Macoilin PF09726.4 CEP10012.1 - 0.081 11.1 5.5 0.079 11.2 3.8 1.0 1 0 0 1 1 1 0 Transmembrane protein RNA_polI_A34 PF08208.6 CEP10012.1 - 0.097 12.3 14.4 0.13 11.9 10.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.3 CEP10012.1 - 0.16 10.6 3.6 0.2 10.3 2.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF904 PF06005.7 CEP10013.1 - 0.047 13.9 0.6 0.09 13.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3233 PF11557.3 CEP10013.1 - 0.16 10.7 0.7 0.17 10.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) DUF1395 PF07160.7 CEP10013.1 - 0.44 9.9 4.3 0.54 9.7 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Crust_neurohorm PF01147.12 CEP10014.1 - 0.045 13.0 0.2 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family JAB PF01398.16 CEP10016.1 - 4.3e-25 87.6 1.0 3.1e-23 81.6 0.7 2.6 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CEP10016.1 - 0.00039 19.9 0.0 0.00072 19.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CEP10016.1 - 0.027 13.9 0.4 0.22 10.9 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) Lzipper-MIP1 PF14389.1 CEP10017.1 - 0.0042 17.1 0.1 0.0093 16.0 0.1 1.5 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 CEP10017.1 - 0.023 14.1 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.1 CEP10017.1 - 0.15 12.4 3.0 0.16 12.4 0.4 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-C4H2 PF10146.4 CEP10017.1 - 0.38 10.7 4.0 0.15 12.1 0.8 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein YjbE PF11106.3 CEP10017.1 - 0.39 10.7 8.0 1.1 9.3 5.6 1.7 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE PEP-utilisers_N PF05524.8 CEP10017.1 - 0.44 10.3 3.5 0.63 9.8 0.3 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DDE_3 PF13358.1 CEP10018.1 - 1.5e-28 99.3 0.0 2.3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP10018.1 - 0.0052 15.9 0.0 0.04 13.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease MULE PF10551.4 CEP10018.1 - 0.025 14.7 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain Na_Ca_ex PF01699.19 CEP10019.1 - 1.4e-39 134.8 22.8 2.6e-22 78.9 7.5 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Neurensin PF14927.1 CEP10019.1 - 0.13 11.6 1.3 0.42 9.9 0.5 2.4 1 1 0 1 1 1 0 Neurensin DUF1103 PF06513.6 CEP10020.1 - 0.0044 16.4 1.5 0.0056 16.0 1.0 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) APG17 PF04108.7 CEP10021.1 - 7.2e-50 169.9 21.4 1e-49 169.5 14.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Vps5 PF09325.5 CEP10021.1 - 0.0078 15.4 2.9 0.0078 15.4 2.0 2.5 3 1 0 3 3 3 1 Vps5 C terminal like Orthopox_F14 PF06076.7 CEP10021.1 - 0.57 10.2 5.5 5 7.2 0.1 3.3 2 1 1 3 3 3 0 Orthopoxvirus F14 protein Prp18 PF02840.10 CEP10021.1 - 0.75 9.6 5.3 0.78 9.5 0.6 2.8 3 0 0 3 3 3 0 Prp18 domain COX14 PF14880.1 CEP10022.1 - 0.025 14.1 1.3 0.034 13.7 0.9 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c assembly CheY-binding PF09078.6 CEP10022.1 - 0.065 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 CheY binding Snf7 PF03357.16 CEP10023.1 - 5.8e-43 146.2 17.3 5.8e-43 146.2 12.0 1.7 1 1 1 2 2 2 1 Snf7 TraC PF07820.7 CEP10023.1 - 0.017 15.2 0.1 0.017 15.2 0.1 2.3 2 0 0 2 2 2 0 TraC-like protein DUF974 PF06159.8 CEP10023.1 - 0.069 12.5 1.3 0.087 12.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF974) ORF6C PF10552.4 CEP10023.1 - 0.08 12.6 2.2 0.16 11.6 0.1 2.3 1 1 1 2 2 2 0 ORF6C domain DUF4442 PF14539.1 CEP10024.1 - 8.3e-16 58.1 0.0 8.7e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4442) Cyt-b5 PF00173.23 CEP10027.1 - 2.3e-21 75.3 0.0 3.5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pribosyl_synth PF14572.1 CEP10028.1 - 2.6e-47 160.9 3.4 7.3e-38 130.1 1.5 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CEP10028.1 - 2.1e-46 156.4 1.3 2.5e-45 152.9 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CEP10028.1 - 6e-13 48.6 1.4 5.2e-12 45.5 0.5 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CEP10028.1 - 0.03 13.5 0.3 0.05 12.7 0.2 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Proteasome PF00227.21 CEP10029.1 - 2.8e-39 134.4 0.0 3.3e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4174 PF13778.1 CEP10029.1 - 0.026 14.6 0.1 2.6 8.1 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4174) Abhydrolase_2 PF02230.11 CEP10030.1 - 6.2e-65 218.6 0.0 7.3e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CEP10030.1 - 7.8e-12 45.1 0.0 1.8e-11 44.0 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP10030.1 - 9.5e-10 38.7 0.2 0.00097 19.0 0.0 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 CEP10030.1 - 5.9e-08 32.4 0.0 2.2e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 CEP10030.1 - 5.1e-07 29.1 0.1 8.8e-06 25.0 0.0 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 CEP10030.1 - 1.9e-05 24.0 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 CEP10030.1 - 0.00051 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.4 CEP10030.1 - 0.00095 18.4 0.0 0.19 10.9 0.0 2.2 1 1 1 2 2 2 2 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 CEP10030.1 - 0.0026 17.3 0.0 0.82 9.2 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 CEP10030.1 - 0.008 15.8 0.0 0.046 13.3 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_1 PF00561.15 CEP10030.1 - 0.014 14.9 0.1 0.35 10.3 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.15 CEP10030.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Abhydro_lipase PF04083.11 CEP10030.1 - 0.053 12.8 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PXPV PF12778.2 CEP10031.1 - 1.3 8.7 7.6 6.1 6.6 1.4 2.2 2 0 0 2 2 2 0 PXPV repeat (3 copies) Ric8 PF10165.4 CEP10032.1 - 3.3e-89 299.7 0.1 4e-89 299.4 0.1 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn FlgD PF03963.9 CEP10032.1 - 0.81 9.8 3.7 1.5 8.9 0.4 2.6 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Enkurin PF13864.1 CEP10033.1 - 0.00056 20.0 1.2 0.00056 20.0 0.8 6.1 6 3 0 6 6 6 1 Calmodulin-binding DUF3450 PF11932.3 CEP10033.1 - 0.0049 16.1 5.2 0.0049 16.1 3.6 5.4 5 1 1 6 6 6 1 Protein of unknown function (DUF3450) ABC_membrane PF00664.18 CEP10034.1 - 3e-68 230.2 43.3 1.6e-38 132.7 5.5 3.7 3 1 1 4 4 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 CEP10034.1 - 1.6e-52 177.4 0.4 2.8e-29 102.1 0.0 3.2 4 0 0 4 4 2 2 ABC transporter SMC_N PF02463.14 CEP10034.1 - 5.2e-11 42.2 0.0 5.7e-05 22.4 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEP10034.1 - 1.4e-05 25.2 0.7 11 5.9 0.1 4.7 3 1 1 4 4 4 0 AAA domain MMR_HSR1 PF01926.18 CEP10034.1 - 4.6e-05 23.3 1.2 0.16 11.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 CEP10034.1 - 7e-05 22.8 0.8 0.3 11.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CEP10034.1 - 0.00012 21.5 0.8 0.081 12.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CEP10034.1 - 0.00024 20.3 0.5 0.064 12.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CEP10034.1 - 0.0008 20.2 1.6 0.18 12.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 CEP10034.1 - 0.00095 18.1 0.0 0.95 8.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 CEP10034.1 - 0.0015 19.0 1.3 0.83 10.1 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 CEP10034.1 - 0.0017 18.2 5.4 0.51 10.1 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 CEP10034.1 - 0.0028 18.0 0.2 1.5 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEP10034.1 - 0.0064 15.9 0.3 0.94 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEP10034.1 - 0.0089 15.4 4.2 0.77 9.1 0.2 2.9 2 1 1 3 3 3 2 AAA-like domain NB-ARC PF00931.17 CEP10034.1 - 0.033 13.0 0.7 0.97 8.2 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 CEP10034.1 - 0.038 13.4 0.2 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 CEP10034.1 - 0.056 13.1 3.5 1.6 8.4 0.5 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CEP10034.1 - 0.064 13.0 5.3 0.08 12.7 0.4 2.6 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 CEP10034.1 - 0.078 12.0 0.0 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 CEP10034.1 - 0.11 12.3 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CEP10034.1 - 0.14 11.5 0.2 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEP10034.1 - 0.26 11.4 4.2 3.6 7.7 0.1 3.3 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 CEP10034.1 - 0.29 10.2 4.1 1.3 8.0 0.5 2.6 2 0 0 2 2 2 0 AIG1 family AAA_30 PF13604.1 CEP10034.1 - 0.77 9.2 2.9 38 3.7 0.1 3.2 3 0 0 3 3 3 0 AAA domain DUF1014 PF06244.7 CEP10035.1 - 1.2e-15 57.8 31.3 1.8e-15 57.2 17.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) UPF0515 PF15135.1 CEP10035.1 - 0.44 9.5 3.0 0.7 8.9 2.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Malate_synthase PF01274.17 CEP10036.1 - 8.2e-226 750.0 0.0 1e-225 749.7 0.0 1.1 1 0 0 1 1 1 1 Malate synthase Glyco_transf_49 PF13896.1 CEP10036.1 - 3e-38 131.6 0.6 3.4e-28 98.6 0.1 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CEP10036.1 - 0.0043 16.1 0.2 0.0083 15.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CEP10036.1 - 0.058 13.7 0.6 0.21 11.9 0.4 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 Pyrophosphatase PF00719.14 CEP10037.1 - 1.8e-47 160.6 0.3 4.5e-47 159.3 0.2 1.7 1 0 0 1 1 1 1 Inorganic pyrophosphatase TPR_11 PF13414.1 CEP10037.1 - 7e-20 70.4 9.0 5.2e-15 54.8 1.4 2.2 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CEP10037.1 - 3.5e-10 39.0 8.3 5.2e-07 29.0 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CEP10037.1 - 1.5e-09 37.0 3.3 0.00012 21.7 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP10037.1 - 2.1e-07 30.7 0.3 4.6e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEP10037.1 - 6.7e-05 23.1 0.6 0.00016 21.9 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP10037.1 - 0.0001 22.6 0.6 0.048 14.3 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP10037.1 - 0.00011 21.7 0.2 0.06 13.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP10037.1 - 0.0018 18.8 0.3 0.32 11.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEP10037.1 - 0.0075 16.1 2.4 0.059 13.2 0.1 3.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 CEP10037.1 - 0.014 15.4 4.6 0.016 15.3 1.2 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CEP10037.1 - 0.084 12.6 4.5 2.3 8.2 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEP10037.1 - 0.16 11.9 0.1 0.85 9.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 CEP10037.1 - 0.18 11.7 1.5 16 5.4 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP10037.1 - 0.75 10.3 4.4 28 5.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.1 CEP10038.1 - 2.7e-21 74.8 11.2 5e-21 74.0 7.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 CEP10038.1 - 6.2e-07 28.9 0.1 1.4e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10038.1 - 1.5e-06 27.9 0.0 4.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CEP10038.1 - 8.4e-06 25.3 8.1 1.6e-05 24.4 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 CEP10038.1 - 0.0017 18.3 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CEP10038.1 - 0.011 15.7 12.2 0.021 14.8 8.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CEP10038.1 - 0.26 11.0 3.9 0.68 9.7 2.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 CEP10038.1 - 0.44 10.2 11.2 0.86 9.3 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HJURP_C PF12347.3 CEP10040.1 - 0.0037 16.8 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat NRDE PF05742.7 CEP10041.1 - 1.2e-56 192.0 0.0 2e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 NRDE protein BAR PF03114.13 CEP10041.1 - 1.2e-47 162.3 0.3 1.9e-47 161.7 0.2 1.2 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 CEP10041.1 - 0.0081 15.5 1.8 0.043 13.1 1.3 2.0 1 1 0 1 1 1 1 Arfaptin-like domain Arb1 PF09692.5 CEP10042.1 - 2.2e-45 155.2 2.7 8.6e-38 130.2 0.5 2.1 1 1 1 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 BUD22 PF09073.5 CEP10042.1 - 0.0041 16.2 7.9 0.0064 15.6 5.5 1.2 1 0 0 1 1 1 1 BUD22 MBOAT_2 PF13813.1 CEP10043.1 - 1.4e-11 44.3 0.2 2.8e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family UCH_1 PF13423.1 CEP10044.1 - 4.3e-34 118.3 0.1 4.3e-34 118.3 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Zip PF02535.17 CEP10044.1 - 0.1 11.5 13.0 0.16 10.9 9.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 CEP10044.1 - 8.2 5.5 12.9 14 4.7 9.0 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Na_H_Exchanger PF00999.16 CEP10045.1 - 1.9e-53 181.4 25.6 2.6e-53 180.9 17.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PAP_RNA-bind PF04926.10 CEP10045.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain DUF3794 PF12673.2 CEP10046.1 - 0.1 12.7 1.0 0.16 12.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) Tetraspannin PF00335.15 CEP10046.1 - 0.49 9.6 3.2 0.65 9.2 2.2 1.1 1 0 0 1 1 1 0 Tetraspanin family FCP1_C PF09309.5 CEP10047.1 - 0.093 12.0 1.9 0.18 11.0 1.3 1.4 1 0 0 1 1 1 0 FCP1, C-terminal RAB3GAP2_N PF14655.1 CEP10047.1 - 0.39 9.6 5.1 0.22 10.4 1.9 1.7 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SNAP PF14938.1 CEP10048.1 - 4.6e-97 324.5 14.6 5.2e-97 324.3 10.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 CEP10048.1 - 0.00057 19.4 19.4 0.002 17.7 2.3 4.2 1 1 4 5 5 5 2 TPR repeat TPR_7 PF13176.1 CEP10048.1 - 0.0062 16.2 12.7 3.4 7.6 0.8 5.8 3 2 2 5 5 5 2 Tetratricopeptide repeat NSF PF02071.15 CEP10048.1 - 0.018 15.4 19.0 0.13 12.8 0.1 6.6 6 2 2 8 8 8 0 Aromatic-di-Alanine (AdAR) repeat TPR_12 PF13424.1 CEP10048.1 - 0.019 14.9 14.9 0.35 10.8 2.4 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 CEP10048.1 - 0.1 12.5 0.4 0.1 12.5 0.3 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Spatacsin_C PF14649.1 CEP10048.1 - 0.18 10.6 2.9 0.76 8.5 0.1 2.4 2 0 0 2 2 2 0 Spatacsin C-terminus TPR_1 PF00515.23 CEP10048.1 - 0.19 11.3 19.2 1.5 8.5 0.4 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP10048.1 - 1.2 9.2 29.9 8 6.6 0.6 7.6 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEP10048.1 - 4.3 8.2 12.7 52 4.8 0.2 4.8 2 2 3 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 CEP10049.1 - 1.6e-34 119.2 0.2 4.1e-24 85.1 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10049.1 - 7.3e-15 54.7 0.1 2.1e-09 36.8 0.0 2.3 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CEP10049.1 - 0.086 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med12 PF09497.5 CEP10050.1 - 3.3e-24 84.6 0.0 9.3e-24 83.1 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 CEP10050.1 - 2.2e-08 33.0 1.1 0.00034 19.2 0.1 2.3 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain zf-C2H2_4 PF13894.1 CEP10051.1 - 1.5e-06 28.1 4.0 0.0015 18.6 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP10051.1 - 5.6e-06 26.3 7.3 0.012 15.9 0.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type INO80_Ies4 PF08193.6 CEP10051.1 - 0.72 9.7 21.3 5.1 6.9 12.1 2.9 2 1 0 2 2 2 0 INO80 complex subunit Ies4 zf-C2H2_jaz PF12171.3 CEP10051.1 - 1.9 8.7 4.3 7.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TT_ORF2 PF02957.10 CEP10051.1 - 3.4 8.4 7.5 30 5.3 0.1 2.5 2 0 0 2 2 2 0 TT viral ORF2 Lipase_3 PF01764.20 CEP10053.1 - 2.4e-07 30.4 0.1 5.6e-07 29.2 0.1 1.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CEP10053.1 - 0.028 14.1 0.0 0.032 14.0 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Tctex-1 PF03645.8 CEP10053.1 - 0.029 14.2 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Tctex-1 family UPF0227 PF05728.7 CEP10053.1 - 0.034 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.2 CEP10053.1 - 0.067 13.0 0.4 0.14 11.9 0.2 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family SOBP PF15279.1 CEP10054.1 - 6 7.1 19.1 3.5 7.9 1.7 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein DEAD PF00270.24 CEP10056.1 - 3e-21 75.6 0.0 1.5e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 CEP10056.1 - 5.3e-20 71.1 0.2 1.1e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 CEP10056.1 - 9.6e-18 63.8 0.0 8.5e-17 60.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 CEP10056.1 - 1e-09 37.9 1.2 1.6e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 HRDC domain ResIII PF04851.10 CEP10056.1 - 0.00095 19.0 0.0 0.0038 17.0 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_Sgs1 PF11408.3 CEP10056.1 - 0.024 14.4 0.1 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 Sgs1 RecQ helicase RRM_1 PF00076.17 CEP10058.1 - 6e-18 64.2 0.0 9.7e-18 63.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10058.1 - 3.3e-15 55.8 0.0 5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10058.1 - 2.1e-10 40.2 0.1 3.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OrfB_Zn_ribbon PF07282.6 CEP10059.1 - 1.7e-07 30.7 0.6 4.8e-07 29.3 0.4 1.9 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Usp PF00582.21 CEP10059.1 - 0.049 13.8 0.1 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Universal stress protein family Sec62 PF03839.11 CEP10059.1 - 0.99 8.7 4.0 1.5 8.1 2.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 ZZ PF00569.12 CEP10060.1 - 0.018 14.6 0.9 0.018 14.6 0.6 2.7 2 1 0 2 2 2 0 Zinc finger, ZZ type hSH3 PF14603.1 CEP10060.1 - 0.022 14.7 1.1 0.03 14.3 0.6 1.5 1 1 0 1 1 1 0 Helically-extended SH3 domain zf-CCHC_3 PF13917.1 CEP10060.1 - 0.031 13.9 10.0 0.048 13.3 0.2 2.7 2 1 0 2 2 2 0 Zinc knuckle DUF1528 PF07515.6 CEP10060.1 - 0.093 12.7 0.5 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1528) zf-CCHC PF00098.18 CEP10060.1 - 0.2 11.6 13.4 0.24 11.3 0.4 3.1 3 1 0 3 3 3 0 Zinc knuckle DUF3795 PF12675.2 CEP10060.1 - 1.3 9.2 11.6 1.3 9.2 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) IBR PF01485.16 CEP10060.1 - 3.2 7.6 12.2 11 5.9 0.9 2.5 1 1 1 2 2 2 0 IBR domain zf-B_box PF00643.19 CEP10060.1 - 4 7.4 8.3 1.6 8.6 0.7 2.6 2 1 0 2 2 2 0 B-box zinc finger DnaJ_CXXCXGXG PF00684.14 CEP10060.1 - 5.6 7.0 13.7 6.9 6.7 4.5 2.2 1 1 1 2 2 2 0 DnaJ central domain COX17 PF05051.8 CEP10061.1 - 5.5e-22 77.5 5.3 9.5e-22 76.7 3.7 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CDC45 PF02724.9 CEP10061.1 - 0.35 8.8 5.3 0.45 8.4 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CEP10061.1 - 2.8 5.7 8.4 3.5 5.4 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 CEP10061.1 - 3.7 7.1 9.3 7.1 6.2 6.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L32p PF01783.18 CEP10062.1 - 9.2e-15 54.5 5.1 1.5e-14 53.9 3.5 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.7 CEP10062.1 - 0.024 14.3 1.0 0.15 11.8 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.2 CEP10062.1 - 0.031 14.0 0.7 0.056 13.2 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CEP10062.1 - 0.041 13.3 2.4 0.086 12.3 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CEP10062.1 - 0.39 10.7 1.9 0.52 10.3 0.2 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 CEP10062.1 - 2.6 7.3 5.7 6.7 6.0 4.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain IF-2B PF01008.12 CEP10063.1 - 3e-80 269.2 0.0 4.9e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family PMT PF02366.13 CEP10064.1 - 6.1e-52 176.4 18.7 5.6e-38 130.6 9.0 2.8 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEP10064.1 - 6.1e-37 127.0 0.8 6.1e-37 127.0 0.5 1.7 2 0 0 2 2 2 1 MIR domain Ins145_P3_rec PF08709.6 CEP10064.1 - 0.00052 19.1 0.0 0.00091 18.3 0.0 1.3 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Fz PF01392.17 CEP10065.1 - 3.5e-06 27.3 5.2 8.1e-06 26.1 3.6 1.6 1 0 0 1 1 1 1 Fz domain DUF4234 PF14018.1 CEP10065.1 - 1.9 8.2 8.2 9.6 6.0 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) PGG PF13962.1 CEP10065.1 - 9.3 5.9 10.5 0.1 12.2 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function Radical_SAM PF04055.16 CEP10066.1 - 8.9e-11 42.2 0.3 1.9e-10 41.1 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Lactamase_B PF00753.22 CEP10067.1 - 8.2e-21 74.5 2.4 1.9e-20 73.3 1.7 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CEP10067.1 - 1.7e-05 24.4 1.3 3.1e-05 23.5 0.8 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEP10067.1 - 0.025 14.2 0.1 0.058 13.1 0.1 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain PIG-P PF08510.7 CEP10069.1 - 7.8e-37 125.7 5.7 1.5e-36 124.8 4.0 1.5 1 0 0 1 1 1 1 PIG-P Gln-synt_C PF00120.19 CEP10070.1 - 3.4e-62 209.9 0.0 4.2e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CEP10070.1 - 1.1e-17 63.4 0.0 1.7e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain GP11 PF08677.5 CEP10070.1 - 0.05 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 GP11 baseplate wedge protein DDE_3 PF13358.1 CEP10071.1 - 9.9e-07 28.6 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP10071.1 - 2.9e-05 24.7 0.0 9.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP10071.1 - 0.00044 20.3 0.0 0.0015 18.6 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 CEP10071.1 - 0.00099 18.5 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.1 CEP10071.1 - 0.0036 17.2 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP10071.1 - 0.0088 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_psq PF05225.11 CEP10071.1 - 0.0089 15.5 0.0 0.028 13.9 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_7 PF02796.10 CEP10071.1 - 0.011 15.5 0.0 5.8 6.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MerR_1 PF13411.1 CEP10071.1 - 0.085 12.6 0.3 0.48 10.2 0.1 2.4 1 1 1 2 2 2 0 MerR HTH family regulatory protein Reticulon PF02453.12 CEP10072.1 - 2.6e-16 59.6 3.7 4.1e-16 59.0 2.5 1.3 1 0 0 1 1 1 1 Reticulon DUF1913 PF08931.5 CEP10072.1 - 0.003 17.3 0.4 0.003 17.3 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1913) Ctr PF04145.10 CEP10072.1 - 0.41 10.6 2.2 0.8 9.7 0.2 2.1 2 1 0 2 2 2 0 Ctr copper transporter family UPF0203 PF05254.7 CEP10073.1 - 2.9e-22 78.3 3.8 5.8e-22 77.3 2.7 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 CEP10073.1 - 0.048 13.5 0.9 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.5 CEP10073.1 - 0.98 9.2 5.6 13 5.6 4.2 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like LSM PF01423.17 CEP10076.1 - 8.9e-21 73.2 0.0 1.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEP10076.1 - 0.0032 17.3 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF669 PF05037.8 CEP10076.1 - 0.028 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Nbas_N PF15492.1 CEP10076.1 - 0.063 12.3 0.0 0.082 11.9 0.0 1.0 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Gemin7 PF11095.3 CEP10076.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Zn_clus PF00172.13 CEP10077.1 - 5.2e-05 23.0 13.4 0.0001 22.1 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArfGap PF01412.13 CEP10078.1 - 5.2e-38 129.4 0.1 5.2e-38 129.4 0.1 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ank_4 PF13637.1 CEP10078.1 - 7.7e-16 58.1 0.9 2.2e-11 43.9 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEP10078.1 - 1.4e-15 57.4 2.6 9.7e-15 54.6 0.5 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP10078.1 - 2e-12 46.9 4.4 2.8e-07 30.5 1.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CEP10078.1 - 3.8e-12 45.3 1.0 4.9e-06 26.0 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat BAR PF03114.13 CEP10078.1 - 4.8e-10 39.3 4.3 9.9e-10 38.3 3.0 1.5 1 0 0 1 1 1 1 BAR domain Ank_3 PF13606.1 CEP10078.1 - 1.1e-09 37.5 0.2 1.1e-05 25.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 CEP10078.1 - 1.2e-09 38.3 0.1 3e-09 37.0 0.1 1.8 1 0 0 1 1 1 1 PH domain Arfaptin PF06456.8 CEP10078.1 - 0.0032 16.8 4.5 0.0084 15.4 3.1 1.7 1 0 0 1 1 1 1 Arfaptin-like domain zf-B_box PF00643.19 CEP10078.1 - 0.11 12.4 0.2 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 B-box zinc finger E1_dh PF00676.15 CEP10079.1 - 3.6e-94 314.8 0.2 4.4e-94 314.5 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 CEP10079.1 - 5e-07 28.8 0.0 7.4e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CEP10079.1 - 0.00086 18.3 0.1 0.0072 15.2 0.0 2.2 2 1 0 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CEP10079.1 - 0.002 17.6 0.1 0.012 15.2 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AMMECR1 PF01871.12 CEP10080.1 - 2.8e-45 153.4 0.0 3.3e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 RHH_2 PF03693.9 CEP10080.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0156) BSD PF03909.12 CEP10081.1 - 3.8e-14 52.1 0.3 3.8e-14 52.1 0.2 2.7 4 0 0 4 4 4 1 BSD domain DUF2939 PF11159.3 CEP10081.1 - 0.053 13.7 0.2 0.99 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Catalase PF00199.14 CEP10083.1 - 7.4e-196 650.3 1.8 9.2e-196 650.0 1.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CEP10083.1 - 1.6e-18 66.3 0.1 3.4e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive WD40 PF00400.27 CEP10084.1 - 9.2e-54 177.5 15.2 7.7e-11 41.4 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 CEP10084.1 - 3.5e-10 39.4 1.4 6.6e-10 38.5 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP10084.1 - 7.4e-10 38.2 1.2 1.5e-09 37.2 0.8 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 CEP10084.1 - 1.2e-07 30.2 4.6 0.2 9.7 0.1 5.9 4 3 1 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CEP10084.1 - 0.0016 17.9 1.3 0.72 9.2 0.1 3.4 2 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 CEP10084.1 - 0.0021 16.9 2.8 3.2 6.4 0.1 4.3 1 1 4 5 5 5 1 Nup133 N terminal like CPSF_A PF03178.10 CEP10084.1 - 0.0093 15.0 0.1 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 CEP10084.1 - 0.013 15.7 0.1 7.2 7.0 0.0 3.4 2 0 0 2 2 2 0 PQQ-like domain PRANC PF09372.5 CEP10084.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Pkinase PF00069.20 CEP10085.1 - 2.1e-66 223.7 0.0 2.5e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10085.1 - 1.6e-41 142.0 0.0 2e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP10085.1 - 0.00061 18.8 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CEP10085.1 - 0.014 14.7 0.5 0.021 14.1 0.0 1.5 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 CEP10085.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Nop14 PF04147.7 CEP10086.1 - 1.3e-07 30.0 15.9 1.4e-07 29.9 11.0 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 CEP10086.1 - 0.00015 20.6 30.0 0.0002 20.2 20.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 CEP10086.1 - 0.00019 19.6 11.6 0.0002 19.5 8.0 1.2 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.7 CEP10086.1 - 0.00067 19.0 16.5 0.0007 18.9 11.4 1.1 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 CEP10086.1 - 0.00099 17.7 17.1 0.0011 17.5 11.9 1.1 1 0 0 1 1 1 1 Daxx Family YL1 PF05764.8 CEP10086.1 - 0.0065 16.0 15.2 0.0081 15.7 10.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SGT1 PF07093.6 CEP10086.1 - 0.019 13.3 10.2 0.024 13.0 7.0 1.3 1 0 0 1 1 1 0 SGT1 protein U79_P34 PF03064.11 CEP10086.1 - 0.028 13.9 8.3 0.042 13.3 5.8 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RRN3 PF05327.6 CEP10086.1 - 0.038 12.1 11.8 0.047 11.8 8.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 CEP10086.1 - 0.048 13.0 12.2 0.059 12.7 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 CEP10086.1 - 0.076 13.0 7.1 0.094 12.7 4.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.5 CEP10086.1 - 0.083 11.9 14.7 0.084 11.9 10.2 1.1 1 0 0 1 1 1 0 BUD22 Rhabdo_ncap PF00945.13 CEP10086.1 - 0.098 11.2 4.9 0.14 10.7 3.4 1.4 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SAPS PF04499.10 CEP10086.1 - 0.1 11.1 2.0 0.099 11.2 1.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop25 PF09805.4 CEP10086.1 - 0.19 11.7 12.2 0.29 11.2 8.5 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) FLO_LFY PF01698.11 CEP10086.1 - 0.2 10.4 5.0 0.26 10.0 3.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CobT PF06213.7 CEP10086.1 - 0.2 10.7 21.7 0.25 10.4 15.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.7 CEP10086.1 - 0.4 9.0 18.7 0.5 8.6 13.0 1.1 1 0 0 1 1 1 0 Mpp10 protein VID27 PF08553.5 CEP10086.1 - 1 7.5 13.8 1.3 7.1 9.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein eIF-3c_N PF05470.7 CEP10086.1 - 1.1 7.2 7.0 1.4 6.8 4.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus IlvB_leader PF08049.6 CEP10086.1 - 1.2 8.9 5.9 0.26 11.0 1.1 2.1 2 0 0 2 2 2 0 IlvB leader peptide TFIIA PF03153.8 CEP10086.1 - 1.9 8.2 34.4 0.1 12.5 19.8 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Trypan_PARP PF05887.6 CEP10086.1 - 3.4 7.4 9.0 7.2 6.4 6.2 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PPP4R2 PF09184.6 CEP10086.1 - 3.6 7.0 25.3 6.2 6.2 17.5 1.4 1 0 0 1 1 1 0 PPP4R2 DUF2076 PF09849.4 CEP10086.1 - 7.6 6.4 21.4 11 6.0 14.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ERG4_ERG24 PF01222.12 CEP10087.1 - 1.1e-142 475.5 21.3 1.3e-142 475.3 14.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 CEP10087.1 - 0.0023 18.0 0.2 0.0023 18.0 0.2 3.5 3 2 1 4 4 4 1 Phospholipid methyltransferase R3H-assoc PF13902.1 CEP10088.1 - 0.00025 20.9 0.3 0.0005 20.0 0.1 1.7 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 CEP10088.1 - 0.0075 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain Abhydrolase_6 PF12697.2 CEP10089.1 - 1.9e-14 54.1 0.3 1.9e-14 54.1 0.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP10089.1 - 1e-07 31.8 0.1 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP10089.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Vps51 PF08700.6 CEP10090.1 - 4.8e-14 51.9 0.1 6.6e-13 48.3 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 CEP10090.1 - 0.0014 18.4 1.2 0.0033 17.3 0.1 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.1 CEP10090.1 - 0.0024 17.6 3.6 0.0055 16.4 0.6 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 AMP-binding PF00501.23 CEP10091.1 - 4.9e-85 285.4 0.0 6.8e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme CBS PF00571.23 CEP10091.1 - 0.058 13.2 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 CBS domain Zip PF02535.17 CEP10092.1 - 2.2e-48 164.9 22.7 3.2e-48 164.3 7.0 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Aconitase_C PF00694.14 CEP10092.1 - 0.0026 17.8 0.0 0.0062 16.6 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain HupE_UreJ PF04955.7 CEP10092.1 - 0.019 14.2 0.9 0.019 14.2 0.6 3.4 4 0 0 4 4 4 0 HupE / UreJ protein DUF204 PF02659.10 CEP10092.1 - 0.78 9.9 8.2 6.2 7.0 2.1 3.8 2 1 0 2 2 2 0 Domain of unknown function DUF FCH PF00611.18 CEP10093.1 - 3.5e-11 43.1 0.7 3.5e-11 43.1 0.5 3.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CEP10093.1 - 0.017 14.7 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 CEP10093.1 - 0.018 14.4 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 SH3 domain BAF1_ABF1 PF04684.8 CEP10093.1 - 3.6 6.3 33.5 0.2 10.4 18.9 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 CEP10093.1 - 6.8 5.5 9.4 1.2 8.0 3.2 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter SMC_N PF02463.14 CEP10094.1 - 7.1e-65 218.3 54.9 5.6e-63 212.1 38.1 3.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CEP10094.1 - 3e-27 94.9 1.5 6.4e-27 93.9 0.2 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CEP10094.1 - 8e-12 45.7 17.6 1.1e-06 28.8 3.8 3.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEP10094.1 - 1.1e-06 28.0 0.0 3.9e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_13 PF13166.1 CEP10094.1 - 0.00018 20.1 30.3 0.00018 20.1 21.0 5.9 3 2 3 6 6 6 3 AAA domain Reo_sigmaC PF04582.7 CEP10094.1 - 0.0004 19.6 30.1 0.035 13.3 1.3 5.8 5 2 1 6 6 6 3 Reovirus sigma C capsid protein ABC_tran PF00005.22 CEP10094.1 - 0.078 13.2 0.0 0.078 13.2 0.0 6.5 3 2 0 3 3 3 0 ABC transporter HisKA_2 PF07568.7 CEP10095.1 - 0.054 13.3 0.1 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase Herpes_TK_C PF08465.5 CEP10095.1 - 0.15 11.5 0.3 0.41 10.1 0.2 1.8 1 1 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal YvbH_ext PF11724.3 CEP10096.1 - 0.34 10.6 2.6 0.72 9.5 1.8 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region Ribosomal_L18ae PF01775.12 CEP10097.1 - 3.4e-55 185.2 3.4 4.4e-55 184.8 2.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PLA2_B PF01735.13 CEP10098.1 - 1.9e-39 135.1 2.1 5.9e-19 67.5 0.0 2.8 3 0 0 3 3 3 2 Lysophospholipase catalytic domain GTP_CH_N PF12471.3 CEP10100.1 - 2.7e-90 301.2 0.0 3.7e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 CEP10100.1 - 1.1e-16 60.4 0.0 1.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.16 CEP10100.1 - 0.12 11.7 0.0 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family UPRTase PF14681.1 CEP10101.1 - 1.6e-63 213.7 0.0 1.8e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CEP10101.1 - 2.1e-05 24.2 0.0 3.5e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain HTH_Tnp_Tc3_2 PF01498.13 CEP10102.1 - 3.5e-09 36.6 1.1 1e-08 35.1 0.5 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 CEP10102.1 - 0.0023 18.0 0.0 0.053 13.6 0.0 2.2 1 1 1 2 2 2 1 Winged helix-turn helix TrmB PF01978.14 CEP10102.1 - 0.0047 16.6 0.0 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_7 PF02796.10 CEP10102.1 - 0.033 14.0 1.8 0.94 9.3 0.1 3.1 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase THP2 PF09432.5 CEP10102.1 - 0.046 13.5 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 Tho complex subunit THP2 HTH_23 PF13384.1 CEP10102.1 - 0.14 11.8 0.2 6.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain MRP-L20 PF12824.2 CEP10103.1 - 4.3e-23 82.0 1.6 7.4e-23 81.3 1.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 ArsC PF03960.10 CEP10103.1 - 1.5e-08 34.6 2.3 3e-08 33.7 0.2 2.4 2 1 1 3 3 3 1 ArsC family DUF1687 PF07955.6 CEP10103.1 - 0.00012 22.0 0.3 0.00027 20.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Intein_splicing PF14890.1 CEP10103.1 - 0.0013 17.7 0.1 0.0016 17.3 0.1 1.1 1 0 0 1 1 1 1 Intein splicing domain Adaptin_binding PF10199.4 CEP10104.1 - 1.7e-08 34.8 7.1 3.5e-08 33.8 4.9 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Miro PF08477.8 CEP10104.1 - 0.082 13.4 0.1 0.4 11.2 0.0 2.1 1 1 0 1 1 1 0 Miro-like protein DUF2218 PF09981.4 CEP10105.1 - 0.038 14.1 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) DUF3550 PF12070.3 CEP10107.1 - 2.6e-163 544.4 14.2 1.5e-160 535.3 9.8 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3550/UPF0682) DUF3731 PF12531.3 CEP10107.1 - 0.051 13.1 0.5 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 DNA-K related protein zf-Tim10_DDP PF02953.10 CEP10108.1 - 2.3e-19 68.4 1.8 2.9e-19 68.1 1.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CEP10108.1 - 0.013 15.0 2.8 0.029 13.8 1.9 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Phasin_2 PF09361.5 CEP10108.1 - 0.014 15.3 0.1 0.17 11.9 0.0 2.0 1 1 1 2 2 2 0 Phasin protein RNA_lig_T4_1 PF09511.5 CEP10108.1 - 0.03 13.7 0.2 0.034 13.6 0.1 1.0 1 0 0 1 1 1 0 RNA ligase FH2 PF02181.18 CEP10109.1 - 1.3e-77 261.1 16.9 1.3e-77 261.1 11.7 2.4 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CEP10109.1 - 3.9e-29 101.4 4.3 1.8e-27 96.0 0.1 2.9 2 0 0 2 2 2 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 CEP10109.1 - 3.8e-15 55.7 1.7 3.8e-10 39.4 0.0 3.5 2 1 1 3 3 3 2 Diaphanous GTPase-binding Domain zf-RING_UBOX PF13445.1 CEP10109.1 - 0.001 18.7 0.4 0.0034 17.0 0.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CEP10109.1 - 0.0032 17.2 0.4 0.0061 16.3 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CEP10109.1 - 0.085 12.5 0.8 0.18 11.4 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP10109.1 - 0.096 12.7 0.5 0.19 11.7 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1752 PF08550.5 CEP10110.1 - 1.1e-11 44.1 3.5 2.1e-11 43.1 2.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RdRP PF05183.7 CEP10114.1 - 2.2e-187 624.3 0.1 3.2e-187 623.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 CEP10114.1 - 8.1e-45 150.3 0.0 1e-15 57.0 0.0 6.1 7 0 0 7 7 7 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10114.1 - 3.1e-27 94.3 0.0 2.6e-11 43.3 0.0 5.8 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10114.1 - 8.8e-17 60.7 0.5 3.6e-08 33.1 0.0 5.3 6 0 0 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP10114.1 - 0.028 14.1 0.3 0.14 11.9 0.0 2.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PIF1 PF05970.9 CEP10115.1 - 5.8e-59 199.8 2.3 4.7e-48 163.9 0.0 3.0 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CEP10115.1 - 7.8e-19 68.0 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CEP10115.1 - 1.3e-07 29.8 0.0 7.2e-05 20.7 0.0 2.3 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.1 CEP10115.1 - 1.3e-05 24.8 0.1 3.5e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CEP10115.1 - 6.1e-05 23.1 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 CEP10115.1 - 7.3e-05 22.8 0.0 0.00026 21.0 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 CEP10115.1 - 0.00028 19.8 0.0 0.00055 18.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 CEP10115.1 - 0.00049 20.3 0.0 0.0015 18.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEP10115.1 - 0.00055 19.9 1.5 0.0024 17.8 0.0 2.5 1 1 1 3 3 3 1 AAA ATPase domain Helicase_RecD PF05127.9 CEP10115.1 - 0.0029 17.2 0.0 0.0082 15.7 0.0 1.8 1 0 0 1 1 1 1 Helicase TrwB_AAD_bind PF10412.4 CEP10115.1 - 0.0044 15.7 0.0 0.0077 14.8 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 CEP10115.1 - 0.0046 16.6 0.1 0.051 13.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 CEP10115.1 - 0.008 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 CEP10115.1 - 0.0081 15.1 0.0 0.032 13.1 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CEP10115.1 - 0.0098 15.1 0.0 0.057 12.6 0.0 2.2 3 0 0 3 3 3 1 PhoH-like protein Viral_helicase1 PF01443.13 CEP10115.1 - 0.013 15.0 0.1 3 7.2 0.1 3.2 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 CEP10115.1 - 0.03 13.0 0.1 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein ABC_tran PF00005.22 CEP10115.1 - 0.054 13.7 0.0 0.054 13.7 0.0 2.4 3 1 0 3 3 1 0 ABC transporter NTPase_1 PF03266.10 CEP10115.1 - 0.056 13.1 0.1 0.77 9.4 0.1 2.4 1 1 0 1 1 1 0 NTPase AAA_14 PF13173.1 CEP10115.1 - 0.057 13.3 0.0 0.23 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CEP10115.1 - 0.08 12.6 0.2 0.41 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CEP10115.1 - 0.088 12.9 0.4 0.52 10.5 0.0 2.5 3 0 0 3 3 2 0 RNA helicase MobB PF03205.9 CEP10115.1 - 0.089 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CEP10115.1 - 0.095 12.2 0.0 0.095 12.2 0.0 2.3 2 0 0 2 2 1 0 P-loop containing region of AAA domain Zn_clus PF00172.13 CEP10116.1 - 2.5e-10 40.1 8.0 4.7e-10 39.1 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRCR_2 PF15494.1 CEP10117.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain DUF148 PF02520.12 CEP10118.1 - 0.09 12.5 0.3 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 Kinesin PF00225.18 CEP10119.1 - 0.00047 18.9 0.3 0.00077 18.2 0.2 1.4 1 1 0 1 1 1 1 Kinesin motor domain Mak16 PF04874.9 CEP10120.1 - 0.86 9.7 30.9 1.1 9.3 21.4 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region HABP4_PAI-RBP1 PF04774.10 CEP10120.1 - 1.2 9.6 15.3 1.3 9.5 10.6 1.1 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family YqfQ PF14181.1 CEP10120.1 - 2.6 8.0 6.0 3 7.8 4.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein Trypan_PARP PF05887.6 CEP10120.1 - 2.9 7.7 17.3 3 7.6 12.0 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 CEP10120.1 - 4.1 6.7 18.2 4.3 6.6 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 CEP10120.1 - 5.9 5.5 36.1 5.8 5.5 25.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Spore_coat_CotO PF14153.1 CEP10120.1 - 6.1 6.2 11.6 6.2 6.2 8.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_Rpc4 PF05132.9 CEP10120.1 - 7.7 6.5 6.7 8.7 6.3 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4390 PF14334.1 CEP10121.1 - 0.048 12.8 0.1 0.096 11.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4390) zf-CCHC PF00098.18 CEP10122.1 - 1.1e-06 28.2 13.1 0.00082 19.1 1.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP10122.1 - 0.018 14.6 10.9 0.55 9.9 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 CEP10122.1 - 0.02 14.3 5.6 0.02 14.3 3.9 2.5 1 1 1 2 2 2 0 Zinc knuckle Helitron_like_N PF14214.1 CEP10123.1 - 1.1e-65 220.8 0.0 1.7e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF2967 PF11179.3 CEP10125.1 - 0.5 9.8 5.1 1.2 8.5 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) rve PF00665.21 CEP10126.1 - 5.2e-22 78.2 0.0 8.2e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP10126.1 - 8.4e-06 25.2 0.0 2.6e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 CEP10126.1 - 1.1 8.7 4.6 1.4 8.3 0.3 2.9 3 0 0 3 3 3 0 Integrase Zinc binding domain Surp PF01805.15 CEP10128.1 - 0.028 14.0 0.3 0.061 12.9 0.2 1.6 1 1 0 1 1 1 0 Surp module RVT_1 PF00078.22 CEP10129.1 - 0.047 13.0 0.0 0.099 11.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2774 PF11242.3 CEP10129.1 - 0.19 11.7 0.4 32 4.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2774) DUF863 PF05904.6 CEP10131.1 - 0.016 13.5 1.6 0.022 13.0 1.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) RVT_1 PF00078.22 CEP10133.1 - 1e-13 51.1 0.4 1.5e-13 50.6 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP10134.1 - 2.2e-05 23.9 0.0 2.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP10136.1 - 4.7e-05 23.6 0.1 8.1e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase EPSP_synthase PF00275.15 CEP10139.1 - 2.6e-123 411.5 0.1 3.9e-123 410.9 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CEP10139.1 - 1.2e-91 306.3 0.2 2.9e-91 305.0 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CEP10139.1 - 4e-57 193.4 0.0 7.8e-57 192.4 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CEP10139.1 - 1.7e-34 118.9 0.0 4.6e-34 117.5 0.0 1.8 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 CEP10139.1 - 1.3e-23 82.8 0.0 3.4e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CEP10139.1 - 1.7e-15 57.2 0.0 5.3e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CEP10139.1 - 4.4e-08 32.7 0.0 1.6e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CEP10139.1 - 7.8e-08 33.1 0.1 5.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEP10139.1 - 0.0029 17.8 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CEP10139.1 - 0.0078 15.8 0.5 0.12 11.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CEP10139.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP10139.1 - 0.014 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CEP10139.1 - 0.046 13.5 0.0 0.82 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CEP10139.1 - 0.055 12.3 0.1 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF3585 PF12130.3 CEP10139.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) DUF2031 PF09592.5 CEP10142.1 - 0.48 9.5 5.1 2.1 7.4 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2031) FlxA PF14282.1 CEP10142.1 - 0.78 9.7 6.5 0.46 10.4 2.1 2.0 2 0 0 2 2 2 0 FlxA-like protein COG5 PF10392.4 CEP10142.1 - 1.2 9.0 6.7 3 7.7 1.8 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 FlaC_arch PF05377.6 CEP10142.1 - 3.1 7.7 5.4 0.76 9.7 0.9 2.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DBD_Tnp_Mut PF03108.10 CEP10143.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase NMT_C PF02799.10 CEP10143.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain RRN3 PF05327.6 CEP10144.1 - 0.13 10.3 2.6 0.16 10.0 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.8 CEP10144.1 - 8.4 4.0 10.0 3.7 5.1 5.3 1.5 2 0 0 2 2 2 0 DNA polymerase phi Na_Ca_ex PF01699.19 CEP10145.1 - 4.2e-40 136.5 30.5 2.1e-24 85.7 5.6 3.4 4 1 1 5 5 5 2 Sodium/calcium exchanger protein DUF605 PF04652.11 CEP10146.1 - 1.8 7.9 23.5 2.1 7.6 16.3 1.0 1 0 0 1 1 1 0 Vta1 like F-box PF00646.28 CEP10147.1 - 2.8e-05 23.6 0.0 7.3e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEP10147.1 - 0.00011 21.8 0.1 0.00034 20.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like Gly_transf_sug PF04488.10 CEP10148.1 - 3.1e-07 30.7 0.6 1.1e-06 28.9 0.1 2.0 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CEP10148.1 - 0.0056 15.8 0.5 0.012 14.7 0.4 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Pkinase PF00069.20 CEP10150.1 - 9.1e-60 201.9 0.0 1.3e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10150.1 - 1.8e-29 102.5 0.0 2.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP10150.1 - 6.2e-05 22.1 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP10150.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.16 CEP10151.1 - 8.8e-37 125.4 0.1 1.2e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Cyclin_N PF00134.18 CEP10152.1 - 7.3e-13 48.1 0.5 2e-12 46.7 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF1878 PF08963.5 CEP10152.1 - 0.059 13.5 0.3 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Mg_trans_NIPA PF05653.9 CEP10153.1 - 5.1e-21 74.9 14.8 8.5e-19 67.6 10.3 2.1 1 1 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CEP10153.1 - 3.7e-05 23.8 0.7 3.7e-05 23.8 0.5 3.7 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 CEP10153.1 - 0.006 16.6 4.0 0.006 16.6 2.8 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3592 PF12158.3 CEP10153.1 - 0.14 11.9 2.0 0.28 10.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) RhoGAP PF00620.22 CEP10154.1 - 1e-41 142.0 0.4 5.3e-41 139.7 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 CEP10154.1 - 7.8e-14 51.7 2.6 8.3e-14 51.6 0.0 2.5 2 1 0 2 2 2 1 PH domain PX PF00787.19 CEP10154.1 - 1.4e-11 44.1 0.0 9.8e-11 41.4 0.0 2.5 1 0 0 1 1 1 1 PX domain PH_11 PF15413.1 CEP10154.1 - 6.4e-09 36.0 0.2 6.4e-09 36.0 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 CEP10154.1 - 0.00015 21.7 0.1 0.0011 18.9 0.0 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_7 PF15408.1 CEP10154.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Exo_endo_phos PF03372.18 CEP10155.1 - 2.4e-21 76.7 0.0 4.1e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S21 PF01165.15 CEP10156.1 - 8.6e-14 50.7 1.7 1.3e-13 50.1 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Exostosin PF03016.10 CEP10157.1 - 6.4e-40 137.0 0.3 8.3e-40 136.7 0.2 1.1 1 0 0 1 1 1 1 Exostosin family HMG_box PF00505.14 CEP10159.1 - 2.5e-19 69.3 2.0 5.1e-19 68.3 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP10159.1 - 6.1e-07 29.7 0.8 1.3e-06 28.6 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 CEP10159.1 - 0.038 13.3 0.9 0.058 12.7 0.3 1.5 1 1 0 1 1 1 0 Mating-type protein MAT alpha 1 Chorion_2 PF03964.10 CEP10160.1 - 2.4 8.7 9.4 0.16 12.5 1.4 2.3 2 0 0 2 2 2 0 Chorion family 2 bZIP_1 PF00170.16 CEP10161.1 - 4.6e-12 45.7 7.4 4.6e-12 45.7 5.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP10161.1 - 2.5e-09 36.8 6.8 2.5e-09 36.8 4.7 1.7 2 0 0 2 2 2 1 Basic region leucine zipper Rad54_N PF08658.5 CEP10161.1 - 0.0094 15.7 1.9 0.016 14.9 1.3 1.4 1 0 0 1 1 1 1 Rad54 N terminal bZIP_Maf PF03131.12 CEP10161.1 - 0.014 15.6 7.8 0.018 15.3 4.2 2.0 1 1 0 1 1 1 0 bZIP Maf transcription factor Cmc1 PF08583.5 CEP10162.1 - 0.0052 16.5 5.9 0.0093 15.7 4.1 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 CEP10162.1 - 0.0058 16.7 2.1 0.008 16.2 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Pet191_N PF10203.4 CEP10162.1 - 0.046 13.7 1.0 0.095 12.7 0.7 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Ndufs5 PF10200.4 CEP10162.1 - 0.11 12.5 4.5 0.17 11.8 3.1 1.5 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.12 CEP10162.1 - 0.38 10.7 9.6 0.26 11.3 3.9 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.8 CEP10162.1 - 0.96 8.9 8.0 0.35 10.3 3.2 1.8 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 CEP10162.1 - 7.5 6.6 7.3 12 5.9 0.9 2.3 1 1 1 2 2 2 0 CHCH domain START PF01852.14 CEP10163.1 - 2e-19 69.7 0.3 3.4e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 START domain Mago_nashi PF02792.9 CEP10164.1 - 2.4e-75 251.0 1.5 2.7e-75 250.8 1.0 1.0 1 0 0 1 1 1 1 Mago nashi protein HMG_box PF00505.14 CEP10165.1 - 4.4e-16 58.8 0.3 4.4e-16 58.8 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP10165.1 - 7.4e-12 45.4 0.3 1.7e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain 2CSK_N PF08521.5 CEP10165.1 - 0.01 15.3 0.3 0.024 14.1 0.2 1.6 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal Ferritin-like PF12902.2 CEP10165.1 - 0.048 13.2 0.4 0.048 13.2 0.3 2.0 2 0 0 2 2 2 0 Ferritin-like Cep57_CLD_2 PF14197.1 CEP10165.1 - 6.8 6.7 13.5 0.86 9.5 4.7 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 PIG-L PF02585.12 CEP10166.1 - 2.4e-24 86.2 0.1 5.4e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase RNA_pol_Rpc4 PF05132.9 CEP10166.1 - 4.7e-22 78.3 0.0 4.7e-22 78.3 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase III RPC4 HLH PF00010.21 CEP10168.1 - 1.6e-13 50.1 1.3 1.6e-13 50.1 0.9 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF3168 PF11367.3 CEP10168.1 - 0.11 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) CK2S PF15011.1 CEP10169.1 - 1.2e-06 28.3 0.1 1.8e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Casein Kinase 2 substrate DUF1804 PF08822.6 CEP10169.1 - 0.011 15.5 0.5 0.061 13.0 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1804) SlyX PF04102.7 CEP10169.1 - 0.1 12.9 0.4 4.3 7.7 0.2 2.3 2 0 0 2 2 2 0 SlyX UNC45-central PF11701.3 CEP10170.1 - 6.6e-19 68.0 7.3 1e-17 64.2 0.2 4.2 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 CEP10170.1 - 4.1e-05 23.7 14.7 0.076 13.3 0.0 6.4 3 2 1 4 4 4 3 HEAT repeats TPR_15 PF13429.1 CEP10170.1 - 0.0014 17.7 4.8 0.089 11.8 1.2 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4266 PF14086.1 CEP10170.1 - 0.028 14.9 1.5 0.11 13.0 1.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) HEAT PF02985.17 CEP10170.1 - 4 7.7 11.0 8.7 6.7 0.0 6.2 8 1 0 8 8 8 0 HEAT repeat Ribosomal_60s PF00428.14 CEP10170.1 - 5.5 7.4 11.5 0.11 12.9 2.0 2.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein HEAT_2 PF13646.1 CEP10171.1 - 2.1e-11 43.9 0.0 0.12 12.6 0.0 6.1 4 3 2 6 6 6 5 HEAT repeats HEAT PF02985.17 CEP10171.1 - 5.6e-11 41.5 4.1 0.2 11.8 0.0 9.3 9 2 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 CEP10171.1 - 3.2e-10 40.1 8.8 0.03 14.8 0.0 8.3 8 2 2 10 10 10 3 HEAT-like repeat Arm PF00514.18 CEP10171.1 - 1.5e-07 30.9 0.3 0.058 13.2 0.0 4.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 CEP10171.1 - 7.5e-06 25.7 0.1 2.9e-05 23.9 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 CEP10171.1 - 5.4e-05 23.4 0.8 0.6 10.5 0.0 5.4 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region CsbD PF05532.7 CEP10172.1 - 1e-11 44.2 14.6 1.7e-09 37.2 3.9 2.0 1 1 1 2 2 2 2 CsbD-like DUF883 PF05957.8 CEP10172.1 - 0.038 14.3 1.2 0.045 14.1 0.2 1.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LRR_4 PF12799.2 CEP10173.1 - 2.6e-07 30.0 9.5 0.019 14.6 0.3 5.5 3 3 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP10173.1 - 1e-05 25.1 11.6 0.00087 18.9 0.9 4.1 3 2 3 6 6 6 5 Leucine rich repeat LRR_7 PF13504.1 CEP10173.1 - 1.1e-05 24.8 13.6 5.2 7.7 0.0 6.4 6 0 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 CEP10173.1 - 1.6e-05 24.3 14.3 3.2 8.1 0.0 5.9 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 CEP10173.1 - 3.3e-05 23.4 15.4 1.1 9.5 0.0 7.4 8 0 0 8 8 8 2 Leucine Rich repeat Ribosomal_L15e PF00827.12 CEP10174.1 - 7.3e-90 299.6 11.4 8.3e-90 299.4 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 ECH PF00378.15 CEP10175.1 - 1.7e-39 135.3 0.0 2.1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CFEM PF05730.6 CEP10176.1 - 8.1 6.3 12.3 4.3 7.2 6.4 2.3 1 1 1 2 2 2 0 CFEM domain Asp PF00026.18 CEP10177.1 - 7e-35 120.7 0.3 1.2e-21 77.3 0.1 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP10177.1 - 9.4e-08 32.1 0.1 4.3e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RVP PF00077.15 CEP10177.1 - 0.064 13.1 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease HA2 PF04408.18 CEP10178.1 - 1.3e-19 70.0 0.0 4.5e-19 68.3 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEP10178.1 - 8.8e-13 48.0 0.0 2.7e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEP10178.1 - 9.8e-13 47.7 0.0 2.3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP10178.1 - 1.1e-07 31.5 0.1 2.5e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEP10178.1 - 3.6e-05 23.9 0.1 0.0001 22.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CEP10178.1 - 0.001 18.9 2.5 0.0032 17.3 0.1 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CEP10178.1 - 0.0071 15.2 0.0 0.017 14.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CEP10178.1 - 0.01 15.3 0.4 0.053 13.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 CEP10178.1 - 0.13 12.6 6.7 0.55 10.5 0.0 3.5 3 1 1 4 4 4 0 ABC transporter AAA_29 PF13555.1 CEP10178.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L16 PF00252.13 CEP10179.1 - 5.6e-34 116.7 0.1 6.7e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.6 CEP10179.1 - 0.15 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein rve PF00665.21 CEP10183.1 - 1.6e-07 31.4 0.0 2.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RVT_3 PF13456.1 CEP10184.1 - 0.00054 19.6 0.0 0.004 16.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase-like RNase_H PF00075.19 CEP10184.1 - 0.027 14.8 0.0 0.09 13.1 0.0 1.8 1 1 1 2 2 2 0 RNase H Tom5 PF10642.4 CEP10184.1 - 0.13 11.9 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Tropomyosin PF00261.15 CEP10184.1 - 0.14 11.1 0.2 0.31 10.0 0.0 1.5 2 0 0 2 2 2 0 Tropomyosin Glyco_transf_20 PF00982.16 CEP10185.1 - 4.7e-162 539.7 0.0 6.9e-162 539.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEP10185.1 - 1.2e-75 253.5 0.0 2.1e-75 252.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Nicastrin PF05450.10 CEP10185.1 - 1.8e-32 112.4 3.3 3.8e-31 108.1 2.3 2.5 1 1 0 1 1 1 1 Nicastrin Lustrin_cystein PF14625.1 CEP10185.1 - 0.19 11.8 6.5 0.021 14.8 0.8 2.2 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Snf7 PF03357.16 CEP10186.1 - 6e-45 152.6 23.1 1.5e-44 151.4 16.0 1.6 1 0 0 1 1 1 1 Snf7 FHA PF00498.21 CEP10186.1 - 0.00016 21.7 0.1 0.00036 20.6 0.1 1.7 1 0 0 1 1 1 1 FHA domain NPV_P10 PF05531.7 CEP10186.1 - 0.36 11.1 13.5 0.24 11.6 2.2 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 CEP10186.1 - 5.8 5.7 14.7 11 4.8 10.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TAF4 PF05236.9 CEP10187.1 - 2.2e-16 59.9 8.7 2.4e-16 59.7 0.0 3.5 4 0 0 4 4 4 2 Transcription initiation factor TFIID component TAF4 family Usp PF00582.21 CEP10188.1 - 3e-25 89.0 0.4 6.6e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Universal stress protein family Oxidored_nitro PF00148.14 CEP10188.1 - 0.049 12.2 0.1 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Chitin_synth_1 PF01644.12 CEP10189.1 - 4.2e-88 293.3 0.1 8.5e-88 292.3 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CEP10189.1 - 5.8e-29 99.6 0.3 1.8e-28 98.0 0.2 1.9 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEP10189.1 - 1.7e-19 69.6 2.8 4e-17 61.7 0.0 2.2 1 1 0 2 2 2 2 Chitin synthase RRM_1 PF00076.17 CEP10189.1 - 1.9e-14 53.0 0.0 6.7e-14 51.2 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10189.1 - 3.6e-11 42.8 0.0 8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyco_trans_2_3 PF13632.1 CEP10189.1 - 2.2e-08 34.0 2.1 2.2e-08 34.0 1.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 RRM_5 PF13893.1 CEP10189.1 - 6.8e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_tranf_2_3 PF13641.1 CEP10189.1 - 0.00028 20.7 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF998 PF06197.8 CEP10189.1 - 8.8 5.5 12.2 0.028 13.7 1.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF998) Kelch_1 PF01344.20 CEP10190.1 - 6.1e-07 28.8 7.5 0.26 10.8 0.5 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CEP10190.1 - 4.8e-06 26.1 1.4 4.1 7.3 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 CEP10190.1 - 1e-05 25.4 8.0 0.043 14.0 0.3 6.0 4 2 2 6 6 6 1 Kelch motif Kelch_4 PF13418.1 CEP10190.1 - 0.0021 17.8 1.7 2.5 7.9 0.1 5.2 4 1 0 4 4 4 1 Galactose oxidase, central domain OLF PF02191.11 CEP10190.1 - 0.0025 17.1 0.3 1.7 7.8 0.0 2.6 1 1 1 2 2 2 2 Olfactomedin-like domain TFR_dimer PF04253.10 CEP10190.1 - 0.042 13.4 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Kelch_3 PF13415.1 CEP10190.1 - 0.27 11.4 1.6 12 6.2 0.1 4.0 3 1 1 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP10190.1 - 1.7 8.6 4.4 3.9 7.5 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 CEP10191.1 - 1.2e-09 37.9 6.5 0.00025 21.0 0.0 5.4 3 1 2 5 5 5 2 Kelch motif Kelch_1 PF01344.20 CEP10191.1 - 1.2e-06 27.9 4.5 0.002 17.6 0.3 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 CEP10191.1 - 2.2e-06 27.2 2.5 0.99 9.2 0.1 5.2 5 2 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 CEP10191.1 - 4.8e-06 26.5 8.0 0.75 10.0 0.4 5.0 4 2 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP10191.1 - 0.00013 21.6 11.5 1.9 8.3 0.4 5.8 4 1 2 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP10191.1 - 0.023 14.6 0.1 3 7.8 0.0 3.6 4 0 0 4 4 4 0 Kelch motif RRP7 PF12923.2 CEP10192.1 - 0.025 14.5 0.3 0.025 14.5 0.2 1.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) HATPase_c_5 PF14501.1 CEP10192.1 - 0.1 12.3 0.1 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 GHKL domain Aa_trans PF01490.13 CEP10193.1 - 3.9e-45 154.0 22.7 5e-45 153.7 15.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAPS PF04499.10 CEP10194.1 - 3.3e-111 372.2 0.9 3.3e-111 372.2 0.6 3.1 2 2 0 2 2 2 1 SIT4 phosphatase-associated protein Trypan_PARP PF05887.6 CEP10194.1 - 0.81 9.4 8.4 2.2 8.0 5.8 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SE PF08491.5 CEP10195.1 - 2.5e-101 338.1 0.1 3.7e-101 337.5 0.1 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CEP10195.1 - 8.7e-12 44.7 0.0 1.5e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CEP10195.1 - 5.4e-06 25.5 0.2 3.7e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 CEP10195.1 - 1.6e-05 23.9 0.0 0.0016 17.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CEP10195.1 - 0.00036 19.7 0.1 0.00097 18.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 CEP10195.1 - 0.00038 19.4 2.1 0.13 11.0 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CEP10195.1 - 0.0014 18.5 0.4 0.0036 17.3 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP10195.1 - 0.0024 17.7 0.1 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CEP10195.1 - 0.0062 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CEP10195.1 - 0.014 15.8 1.1 0.11 12.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP10195.1 - 0.026 13.6 0.1 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CEP10195.1 - 0.051 12.0 0.0 0.081 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 CEP10195.1 - 0.051 13.3 0.6 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.16 CEP10195.1 - 0.068 12.7 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CEP10195.1 - 0.071 12.7 0.8 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CEP10195.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus B3_4 PF03483.12 CEP10196.1 - 2.4e-27 95.4 0.1 4.4e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CEP10196.1 - 4.8e-16 58.3 0.0 1.4e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase B5 domain Herpes_V23 PF01802.12 CEP10196.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF2740 PF10872.3 CEP10196.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) SH3BGR PF04908.10 CEP10197.1 - 8e-14 51.3 2.7 1.1e-13 50.9 0.0 2.8 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 CEP10197.1 - 0.00016 21.6 0.0 0.00055 19.8 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin LRR_4 PF12799.2 CEP10198.1 - 1e-29 101.6 33.9 8e-06 25.3 0.0 8.6 5 2 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP10198.1 - 2.1e-27 94.6 36.7 4.4e-08 32.7 0.2 8.2 5 2 2 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 CEP10198.1 - 2.3e-10 39.0 47.9 1.2 9.4 0.0 14.1 12 2 2 14 14 14 5 Leucine Rich Repeat LRR_6 PF13516.1 CEP10198.1 - 1.2e-05 24.8 27.2 0.38 10.9 0.0 10.1 9 3 3 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.1 CEP10198.1 - 2.3e-05 24.0 9.9 0.39 10.2 0.2 5.2 2 1 2 5 5 5 3 Leucine-rich repeat LRR_7 PF13504.1 CEP10198.1 - 0.0096 15.9 44.7 9.4 6.9 0.0 13.2 15 0 0 15 15 15 3 Leucine rich repeat zf-C3HC4_3 PF13920.1 CEP10199.1 - 0.11 12.1 3.0 0.19 11.4 2.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF202 PF02656.10 CEP10200.1 - 3.1e-12 46.5 4.0 3.1e-12 46.5 2.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1049 PF06305.6 CEP10200.1 - 0.1 12.0 0.3 0.1 12.0 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) DUF3149 PF11346.3 CEP10200.1 - 0.67 9.5 4.7 0.43 10.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Sarcolipin PF05366.6 CEP10200.1 - 9.7 5.6 7.5 2.9 7.3 0.2 2.8 3 0 0 3 3 3 0 Sarcolipin Alg14 PF08660.6 CEP10201.1 - 4.6e-57 192.7 0.0 7.8e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Aminotran_1_2 PF00155.16 CEP10201.1 - 1.4e-55 188.7 0.0 2.1e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEP10201.1 - 0.0001 21.5 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase RRM_1 PF00076.17 CEP10202.1 - 3.9e-49 164.1 1.3 8.6e-22 76.5 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10202.1 - 1.6e-32 111.3 0.1 2.8e-16 59.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10202.1 - 7.9e-24 83.2 0.3 1.5e-09 37.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CEP10202.1 - 9.2e-22 77.1 0.2 1.9e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 CEP10202.1 - 6.7e-05 22.6 0.2 0.027 14.3 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif DUF566 PF04484.7 CEP10202.1 - 1.9 7.9 22.7 3.2 7.1 15.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) MIP-T3 PF10243.4 CEP10202.1 - 4.3 5.6 22.4 5.7 5.2 15.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-H2C2_2 PF13465.1 CEP10203.1 - 5.4e-09 35.8 18.1 3.7e-07 30.1 0.4 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP10203.1 - 9e-08 32.0 8.7 5.4e-05 23.2 2.0 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 CEP10203.1 - 2.8e-05 24.1 0.7 0.00012 22.1 0.5 2.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CEP10203.1 - 9.4e-05 22.4 5.4 0.0043 17.2 1.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP10203.1 - 0.016 15.0 3.4 0.077 12.9 0.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP10203.1 - 0.031 14.4 0.4 0.031 14.4 0.3 3.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 CEP10203.1 - 0.094 12.4 4.3 4.2 7.1 0.3 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PAT1 PF09770.4 CEP10203.1 - 3.1 5.9 23.9 3.7 5.6 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mito_fiss_reg PF05308.6 CEP10203.1 - 5.5 6.2 13.2 3.8 6.8 7.6 1.8 1 1 0 1 1 1 0 Mitochondrial fission regulator zf-DHHC PF01529.15 CEP10204.1 - 1e-07 31.5 4.2 1e-07 31.5 2.9 3.3 1 1 2 3 3 3 1 DHHC palmitoyltransferase AMP-binding PF00501.23 CEP10205.1 - 1.3e-68 231.3 0.3 1.6e-29 102.5 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 CEP10205.1 - 1.4e-10 41.6 3.1 1.4e-10 41.6 2.1 3.2 2 1 0 2 2 2 1 DMAP1-binding Domain PAT1 PF09770.4 CEP10205.1 - 0.42 8.8 41.4 0.77 7.9 28.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_5 PF12695.2 CEP10207.1 - 2e-19 69.7 0.0 3.2e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP10207.1 - 8.5e-12 45.4 0.0 6.4e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cation_efflux PF01545.16 CEP10207.1 - 7.8e-11 41.5 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family Abhydrolase_2 PF02230.11 CEP10207.1 - 0.00034 20.1 0.0 0.012 15.0 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 CEP10207.1 - 0.009 15.5 0.0 0.87 9.0 0.0 3.0 1 1 2 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEP10207.1 - 0.02 14.1 0.0 0.19 10.9 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.8 CEP10207.1 - 0.072 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) WD40 PF00400.27 CEP10209.1 - 7.2e-33 111.2 3.0 1e-08 34.7 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CEP10209.1 - 0.0019 16.5 0.0 0.42 8.8 0.0 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 CEP10209.1 - 0.013 13.6 1.3 1.9 6.5 0.0 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Mt_ATP-synt_B PF05405.9 CEP10210.1 - 4.5e-46 156.2 6.9 6.1e-46 155.8 4.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) EF-hand_like PF09279.6 CEP10210.1 - 0.0046 16.9 0.2 0.16 12.0 0.0 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1539 PF07560.6 CEP10210.1 - 0.12 12.2 1.3 0.21 11.4 0.9 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) TFIIE_beta PF02186.10 CEP10211.1 - 1.4e-12 47.3 0.4 5e-12 45.6 0.2 2.0 1 0 0 1 1 1 1 TFIIE beta subunit core domain HSF_DNA-bind PF00447.12 CEP10212.1 - 6.2e-31 106.6 0.6 6.2e-31 106.6 0.4 2.5 3 1 0 3 3 3 1 HSF-type DNA-binding Response_reg PF00072.19 CEP10212.1 - 9.4e-26 90.0 0.3 3.5e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain DUF1664 PF07889.7 CEP10212.1 - 0.028 14.2 2.7 0.069 12.9 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF725 PF05267.7 CEP10212.1 - 3.9 7.3 8.6 0.43 10.4 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF725) Pkinase PF00069.20 CEP10213.1 - 1.3e-42 145.7 0.2 1.3e-37 129.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10213.1 - 5.2e-22 78.1 0.0 2.8e-20 72.4 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP10213.1 - 8.5e-05 21.6 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CEP10213.1 - 0.011 14.5 1.4 0.02 13.7 0.8 1.4 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPP1 PF10341.4 CEP10213.1 - 0.034 14.1 0.1 0.93 9.5 0.1 2.6 1 1 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD APH PF01636.18 CEP10213.1 - 0.047 13.4 0.1 0.27 10.9 0.2 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-H2C2_2 PF13465.1 CEP10214.1 - 1.3e-11 44.1 21.7 1.3e-06 28.4 4.0 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP10214.1 - 1.3e-10 41.0 12.1 1.4e-05 25.0 2.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP10214.1 - 3.8e-08 33.1 10.6 0.0015 18.7 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 CEP10214.1 - 0.045 13.8 0.6 0.077 13.0 0.3 1.5 1 1 0 1 1 1 0 Rtr1/RPAP2 family zf-C2H2_jaz PF12171.3 CEP10214.1 - 0.2 11.8 3.0 0.8 9.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CEP10214.1 - 0.37 10.9 3.6 0.73 10.0 2.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.4 CEP10214.1 - 1.3 8.4 3.8 16 4.8 2.6 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) RNase_PH PF01138.16 CEP10215.1 - 1.5e-25 89.9 0.0 2.3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CEP10215.1 - 4.7e-06 26.4 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MFS_1 PF07690.11 CEP10216.1 - 4.8e-21 74.8 51.0 3.2e-11 42.5 6.2 3.6 1 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.11 CEP10216.1 - 7.2e-16 57.9 2.6 7.2e-16 57.9 1.8 2.4 2 1 0 2 2 2 1 Nucleoside H+ symporter MFS_1_like PF12832.2 CEP10216.1 - 6.2e-08 32.3 1.1 6.2e-08 32.3 0.7 3.6 3 1 1 4 4 4 1 MFS_1 like family LacY_symp PF01306.14 CEP10216.1 - 9.1e-07 27.7 2.9 9.1e-07 27.7 2.0 2.2 2 1 0 2 2 2 1 LacY proton/sugar symporter ATG22 PF11700.3 CEP10216.1 - 1.5e-05 23.7 22.1 0.0036 15.8 5.3 2.4 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 CEP10216.1 - 0.00016 20.2 21.4 0.026 12.9 2.9 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein DUF3317 PF11779.3 CEP10216.1 - 0.028 13.8 0.1 0.028 13.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) DNA_pol_B_thumb PF14791.1 CEP10216.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta thumb SapB_1 PF05184.10 CEP10217.1 - 0.16 11.8 0.4 0.55 10.1 0.3 2.0 1 0 0 1 1 1 0 Saposin-like type B, region 1 WD40 PF00400.27 CEP10218.1 - 3e-35 118.8 2.3 1.3e-09 37.5 0.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 CEP10218.1 - 8.7e-07 27.4 0.2 0.0063 14.7 0.0 3.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CEP10218.1 - 0.024 14.0 0.1 1.3 8.4 0.1 2.6 1 1 0 1 1 1 0 PQQ-like domain ORC2 PF04084.9 CEP10219.1 - 2.6e-107 358.4 0.0 4.1e-107 357.7 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 RhoGAP PF00620.22 CEP10220.1 - 2.1e-44 150.8 0.1 4.2e-44 149.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Tox-ODYAM1 PF15642.1 CEP10220.1 - 0.0042 15.8 2.1 0.0088 14.7 1.5 1.5 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus TarH PF02203.10 CEP10220.1 - 0.1 12.4 3.6 0.71 9.6 1.5 2.5 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF2569 PF10754.4 CEP10221.1 - 0.0021 18.3 4.3 0.0032 17.6 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) Adaptin_N PF01602.15 CEP10222.1 - 2.9e-46 157.8 13.4 4e-46 157.4 9.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.1 CEP10222.1 - 2e-08 34.4 0.9 6.7e-08 32.7 0.2 2.2 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.1 CEP10222.1 - 3.2e-05 24.1 0.1 0.00062 19.9 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.2 CEP10222.1 - 0.00059 19.7 6.7 0.0013 18.6 1.7 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Virulence_RhuM PF13310.1 CEP10222.1 - 0.025 13.5 0.1 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Virulence protein RhuM family SRF-TF PF00319.13 CEP10223.1 - 3.3e-23 80.6 0.2 4.6e-23 80.1 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PAT1 PF09770.4 CEP10223.1 - 0.24 9.6 19.0 0.28 9.3 13.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BOP1NT PF08145.7 CEP10224.1 - 0.014 15.1 0.8 0.12 12.1 0.5 2.1 1 1 0 1 1 1 0 BOP1NT (NUC169) domain DDE_3 PF13358.1 CEP10225.1 - 9.9e-19 67.5 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP10225.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Ribosomal_S13 PF00416.17 CEP10226.1 - 4.9e-38 129.8 1.4 6.7e-38 129.4 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CEP10226.1 - 0.0085 14.6 0.0 0.0098 14.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 CEP10226.1 - 0.056 12.2 0.0 0.1 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) Pkinase PF00069.20 CEP10227.1 - 7.6e-73 244.8 0.0 1.3e-72 244.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10227.1 - 9.1e-34 116.6 0.0 1.5e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP10227.1 - 5.7e-06 25.4 0.0 5.3e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Aconitase PF00330.15 CEP10228.1 - 6.6e-164 545.7 0.6 6.2e-163 542.5 0.4 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEP10228.1 - 7.3e-41 139.3 0.1 1.6e-40 138.2 0.1 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1993 PF09351.5 CEP10228.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) SR-25 PF10500.4 CEP10229.1 - 0.00036 20.0 24.8 0.00037 20.0 3.8 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein VIT1 PF01988.14 CEP10229.1 - 1.7 8.0 4.2 0.53 9.7 0.5 2.0 2 0 0 2 2 2 0 VIT family LAT PF15234.1 CEP10231.1 - 0.028 13.8 9.5 0.022 14.2 5.4 1.5 1 1 0 1 1 1 0 Linker for activation of T-cells Nucleo_P87 PF07267.6 CEP10231.1 - 0.034 12.8 3.2 0.036 12.7 2.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mak16 PF04874.9 CEP10231.1 - 0.072 13.1 12.0 0.11 12.5 8.3 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region Nucleoplasmin PF03066.10 CEP10231.1 - 0.48 9.9 13.2 0.67 9.4 9.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 CEP10231.1 - 0.62 9.8 5.5 0.88 9.3 3.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 CEP10231.1 - 0.88 9.2 6.7 1.5 8.5 4.7 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 CEP10231.1 - 1.7 7.8 5.5 2.3 7.3 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 CEP10231.1 - 2.2 6.9 12.8 3.2 6.3 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myc_N PF01056.13 CEP10231.1 - 3.6 6.6 16.3 5.3 6.1 11.3 1.3 1 1 0 1 1 1 0 Myc amino-terminal region VID27 PF08553.5 CEP10231.1 - 4.8 5.2 8.7 6 4.9 6.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein RNA_pol_3_Rpc31 PF11705.3 CEP10231.1 - 5.3 6.9 14.1 7.8 6.3 9.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.7 CEP10231.1 - 6.1 5.4 10.7 8.6 4.9 7.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein BSP_II PF05432.6 CEP10232.1 - 0.019 14.2 7.3 0.026 13.7 5.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 CEP10232.1 - 0.069 11.0 5.0 0.085 10.7 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family PAT1 PF09770.4 CEP10232.1 - 0.072 11.3 11.0 0.074 11.2 7.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleoplasmin PF03066.10 CEP10232.1 - 0.24 10.8 12.5 0.39 10.2 8.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 CEP10232.1 - 0.39 10.3 7.8 0.54 9.8 5.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 CEP10232.1 - 0.64 9.6 6.0 1.1 8.9 4.2 1.3 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.6 CEP10232.1 - 0.96 8.0 4.3 1 7.9 3.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.7 CEP10232.1 - 3 7.0 8.4 4.6 6.3 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4106 PF13388.1 CEP10232.1 - 3.4 6.5 14.0 4.3 6.1 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RXT2_N PF08595.6 CEP10232.1 - 4.2 7.1 8.9 6.8 6.4 6.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Tom22 PF04281.8 CEP10232.1 - 5.4 6.5 7.8 9.2 5.7 5.4 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF4611 PF15387.1 CEP10232.1 - 6.2 7.0 10.9 11 6.2 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.9 CEP10232.1 - 9.1 4.1 7.4 12 3.8 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 CEP10233.1 - 0.25 9.4 18.9 0.37 8.8 13.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.4 CEP10233.1 - 0.37 9.4 39.3 0.89 8.2 27.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RR_TM4-6 PF06459.7 CEP10233.1 - 0.47 10.3 14.9 0.68 9.7 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop25 PF09805.4 CEP10233.1 - 0.88 9.6 28.2 0.48 10.4 16.9 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) V_ATPase_I PF01496.14 CEP10233.1 - 0.93 7.2 4.6 1.2 6.8 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.7 CEP10233.1 - 1.3 7.6 6.6 2.1 7.0 4.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.1 CEP10233.1 - 1.6 8.0 19.0 2.7 7.3 13.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO YqfQ PF14181.1 CEP10233.1 - 1.9 8.4 12.2 4.4 7.3 8.4 1.7 1 0 0 1 1 1 0 YqfQ-like protein RNA_polI_A34 PF08208.6 CEP10233.1 - 2.7 7.6 13.6 5.2 6.6 9.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FYDLN_acid PF09538.5 CEP10233.1 - 2.8 8.5 35.2 4.7 7.8 18.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CobT PF06213.7 CEP10233.1 - 2.8 6.9 34.1 5 6.1 23.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 CEP10233.1 - 2.9 6.2 36.8 0.5 8.7 22.9 1.6 2 0 0 2 2 2 0 Daxx Family BTV_NS2 PF04514.7 CEP10233.1 - 3.2 6.5 16.8 5.5 5.7 11.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CENP-T PF15511.1 CEP10233.1 - 3.6 6.7 28.4 6.1 5.9 19.7 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Nucleo_P87 PF07267.6 CEP10233.1 - 4 5.9 10.0 5.9 5.4 6.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pox_Ag35 PF03286.9 CEP10233.1 - 4.1 6.8 23.2 15 5.0 13.6 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Serinc PF03348.10 CEP10233.1 - 4.1 5.9 4.8 6 5.4 3.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4045 PF13254.1 CEP10233.1 - 4.3 6.5 8.3 6.8 5.8 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Paf1 PF03985.8 CEP10233.1 - 5.2 5.6 28.8 8.6 4.9 20.0 1.3 1 0 0 1 1 1 0 Paf1 CKAP2_C PF15297.1 CEP10233.1 - 5.7 5.6 14.7 9.6 4.9 10.2 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SDA1 PF05285.7 CEP10233.1 - 5.7 6.1 38.1 0.2 10.9 20.1 2.0 2 0 0 2 2 2 0 SDA1 Ycf1 PF05758.7 CEP10233.1 - 6.5 4.3 14.0 8.1 4.0 9.7 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 CEP10233.1 - 8.4 6.3 19.4 3.1 7.7 11.8 1.5 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 bZIP_1 PF00170.16 CEP10236.1 - 1.9e-06 27.7 21.3 2.5e-05 24.1 14.7 2.2 1 1 0 1 1 1 1 bZIP transcription factor HAUS6_N PF14661.1 CEP10236.1 - 0.00011 21.6 4.3 0.00018 20.9 3.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus NYD-SP28_assoc PF14775.1 CEP10236.1 - 0.0013 18.3 5.0 0.0032 17.1 3.5 1.7 1 0 0 1 1 1 1 Sperm tail C-terminal domain Retrotrans_gag PF03732.12 CEP10236.1 - 0.0067 16.4 1.1 0.019 15.0 0.7 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein DUF3450 PF11932.3 CEP10236.1 - 0.012 14.9 2.8 0.019 14.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.6 CEP10236.1 - 0.018 14.5 2.4 0.03 13.7 1.7 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 SOBP PF15279.1 CEP10236.1 - 0.032 14.6 7.6 0.048 14.0 5.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DivIC PF04977.10 CEP10236.1 - 0.24 10.9 6.1 0.19 11.2 3.0 1.7 1 1 0 1 1 1 0 Septum formation initiator PEARLI-4 PF05278.7 CEP10236.1 - 0.62 9.3 5.3 1.3 8.2 3.7 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Adeno_PIX PF03955.9 CEP10236.1 - 1.2 9.7 4.7 3.4 8.2 1.4 2.7 2 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF4337 PF14235.1 CEP10236.1 - 4.2 7.1 7.2 8.8 6.1 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_2 PF07716.10 CEP10236.1 - 9.8 6.0 26.5 1.3 8.8 5.4 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Aminotran_1_2 PF00155.16 CEP10237.1 - 1.1e-21 77.2 0.0 1.3e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_C27 PF05407.7 CEP10237.1 - 0.0046 16.7 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Rubella virus endopeptidase Aminotran_MocR PF12897.2 CEP10237.1 - 0.0049 15.4 0.0 0.0079 14.8 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Kinesin-relat_1 PF12711.2 CEP10238.1 - 0.15 12.4 1.1 3.9 7.9 0.1 2.3 1 1 0 2 2 2 0 Kinesin motor CUE PF02845.11 CEP10239.1 - 0.062 12.8 0.9 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 CUE domain CENP-Q PF13094.1 CEP10239.1 - 0.074 13.0 0.0 0.083 12.9 0.0 1.0 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1789 PF08748.6 CEP10239.1 - 0.12 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) Phage_integrase PF00589.17 CEP10240.1 - 0.046 13.3 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family DEC-1_N PF04625.8 CEP10242.1 - 1.9 7.0 12.5 3 6.4 8.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AftA_C PF12249.3 CEP10244.1 - 0.094 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal FliT PF05400.8 CEP10245.1 - 0.16 12.4 1.3 0.28 11.6 0.9 1.4 1 0 0 1 1 1 0 Flagellar protein FliT AAA_13 PF13166.1 CEP10246.1 - 0.07 11.5 0.0 0.072 11.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain Retrotrans_gag PF03732.12 CEP10247.1 - 4.1e-06 26.7 0.0 1e-05 25.4 0.0 1.7 2 1 0 2 2 2 1 Retrotransposon gag protein Cytochrom_C550 PF14495.1 CEP10247.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain Head-tail_con PF12236.3 CEP10247.1 - 0.08 11.3 0.1 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein DDE_3 PF13358.1 CEP10248.1 - 6.4e-15 55.1 0.0 3.4e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease PIF1 PF05970.9 CEP10250.1 - 5.7e-05 22.2 0.0 7.3e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 CEP10250.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CEP10250.1 - 0.016 14.6 0.1 5.5 6.3 0.1 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein T2SE PF00437.15 CEP10250.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Exo_endo_phos_2 PF14529.1 CEP10254.1 - 4.9e-16 58.4 0.3 1e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP10254.1 - 3.5e-07 30.4 0.3 4.9e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF863 PF05904.6 CEP10257.1 - 0.0035 15.6 4.1 0.0038 15.6 2.8 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF863) zf-CCHC PF00098.18 CEP10258.1 - 0.066 13.1 2.2 0.11 12.4 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 CEP10261.1 - 0.0051 16.1 0.1 0.0098 15.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP10262.1 - 4.6e-20 71.9 0.0 7.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP10262.1 - 0.0035 16.8 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain OrfB_Zn_ribbon PF07282.6 CEP10263.1 - 0.0058 16.2 1.4 0.0062 16.1 0.4 1.5 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Acid_phosphat_B PF03767.9 CEP10263.1 - 0.066 12.5 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ribosomal_L28e PF01778.12 CEP10263.1 - 0.086 13.2 0.1 0.09 13.1 0.1 1.1 1 0 0 1 1 1 0 Ribosomal L28e protein family Pkinase PF00069.20 CEP10264.1 - 1.5e-56 191.4 0.1 4.4e-56 189.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10264.1 - 2.1e-30 105.6 0.2 3.8e-29 101.5 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP10264.1 - 0.0022 17.0 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family NTP_transferase PF00483.18 CEP10265.1 - 5e-51 173.3 0.0 7.8e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CEP10265.1 - 5.4e-12 44.6 7.1 2.7e-09 36.1 2.5 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CEP10265.1 - 1.6e-10 41.3 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CEP10265.1 - 1.5e-06 27.6 1.9 1.5e-06 27.6 1.3 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF2810 PF10928.3 CEP10265.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) SRP54 PF00448.17 CEP10265.1 - 0.05 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CTP_transf_3 PF02348.14 CEP10265.1 - 0.08 12.5 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase Glycos_transf_3 PF00591.16 CEP10267.1 - 1.2e-87 293.5 1.5 1.3e-87 293.4 0.6 1.3 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CEP10267.1 - 1e-14 53.8 0.0 2.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF202 PF02656.10 CEP10268.1 - 3.3e-12 46.4 5.0 3.3e-12 46.4 3.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CoA_binding_3 PF13727.1 CEP10268.1 - 0.0033 17.2 2.0 0.0039 17.0 1.4 1.2 1 0 0 1 1 1 1 CoA-binding domain 7TMR-DISM_7TM PF07695.6 CEP10268.1 - 0.01 15.5 2.0 0.015 14.9 1.4 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling Bax1-I PF01027.15 CEP10268.1 - 0.02 14.5 1.5 0.026 14.1 1.0 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Cyt_c_ox_IV PF12270.3 CEP10268.1 - 0.026 14.2 0.2 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV MARVEL PF01284.18 CEP10268.1 - 0.98 9.2 5.6 2.2 8.0 3.9 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF4131 PF13567.1 CEP10268.1 - 3.8 6.8 7.4 11 5.3 5.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) PAH PF02671.16 CEP10269.1 - 4.2e-46 154.3 5.0 4.5e-18 64.6 0.9 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CEP10269.1 - 8.9e-35 118.4 1.8 2.3e-34 117.1 0.2 2.4 2 0 0 2 2 2 1 Sin3 family co-repressor HAMP PF00672.20 CEP10270.1 - 1.1e-222 720.7 94.0 2.7e-09 37.0 0.1 28.2 27 0 0 27 27 27 26 HAMP domain HATPase_c PF02518.21 CEP10270.1 - 8.1e-31 106.0 0.1 5.8e-30 103.2 0.1 2.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEP10270.1 - 8.1e-27 93.4 2.1 7.1e-25 87.2 0.2 3.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 CEP10270.1 - 2.8e-18 65.6 2.6 2.8e-17 62.4 0.4 4.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.12 CEP10270.1 - 2.7e-12 46.2 15.6 28 4.5 0.0 18.3 22 0 0 22 22 22 0 Helix-turn-helix domain, rpiR family HMG_box PF00505.14 CEP10270.1 - 0.00013 22.1 0.0 68 3.8 0.0 7.2 9 0 0 9 9 9 0 HMG (high mobility group) box SPX PF03105.14 CEP10270.1 - 0.2 11.3 9.4 0.69 9.6 6.5 1.8 1 0 0 1 1 1 0 SPX domain SOBP PF15279.1 CEP10270.1 - 1.9 8.7 2.9 3.8 7.8 2.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein SpoIIID PF12116.3 CEP10270.1 - 5.2 7.0 52.6 45 4.0 0.0 17.3 23 0 0 23 23 23 0 Stage III sporulation protein D Pox_A_type_inc PF04508.7 CEP10270.1 - 8.1 6.5 12.5 5.4 7.0 0.0 6.8 9 0 0 9 9 9 0 Viral A-type inclusion protein repeat Homeobox PF00046.24 CEP10271.1 - 5.5e-19 67.5 2.6 1.4e-18 66.2 1.8 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP10271.1 - 0.013 15.1 0.1 0.034 13.8 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain WBP-1 PF11669.3 CEP10271.1 - 0.24 11.4 3.4 1.3 9.1 0.1 2.7 3 0 0 3 3 3 0 WW domain-binding protein 1 DUF4300 PF14133.1 CEP10271.1 - 0.64 9.2 5.1 0.081 12.1 0.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4300) DUF733 PF05306.6 CEP10271.1 - 1.2 9.4 13.7 7 7.0 2.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF733) LcrG PF07216.7 CEP10271.1 - 1.7 8.6 4.8 6.8 6.7 0.1 2.9 3 0 0 3 3 3 0 LcrG protein SieB PF14163.1 CEP10271.1 - 1.8 8.1 7.0 0.62 9.6 0.4 2.5 2 1 1 3 3 3 0 Superinfection exclusion protein B rve PF00665.21 CEP10273.1 - 9.7e-24 83.7 0.0 1.3e-22 80.1 0.0 2.8 4 0 0 4 4 4 1 Integrase core domain RVT_1 PF00078.22 CEP10273.1 - 2.3e-05 23.8 0.0 0.0002 20.8 0.0 2.3 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CEP10273.1 - 7.5e-05 22.1 0.0 0.00049 19.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Pro_isomerase PF00160.16 CEP10276.1 - 1.6e-46 158.3 0.2 2.6e-46 157.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CEP10276.1 - 2e-09 36.9 7.3 1.7e-07 30.7 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CEP10276.1 - 6.5e-06 25.6 7.7 0.037 13.9 0.3 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP10276.1 - 0.00019 20.8 8.3 0.0031 17.0 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP10276.1 - 0.26 11.2 2.8 2.8 7.9 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP10276.1 - 2.7 7.9 7.1 0.94 9.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin_4 PF13462.1 CEP10277.1 - 1.9e-13 50.7 0.0 2.6e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 CEP10277.1 - 0.00041 19.9 2.2 0.072 12.6 0.7 2.3 1 1 0 2 2 2 2 DSBA-like thioredoxin domain Proteasome PF00227.21 CEP10278.1 - 1.4e-44 151.6 0.0 1.6e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3292 PF11696.3 CEP10279.1 - 2.9e-10 38.7 4.5 3.9e-06 25.0 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 CEP10279.1 - 3.3e-06 26.6 3.9 9.9e-06 25.1 0.1 2.3 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.6 CEP10279.1 - 5.3e-05 22.1 2.8 0.0021 16.9 0.2 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Reticulon PF02453.12 CEP10279.1 - 0.0028 17.2 0.6 1.4 8.5 0.1 2.8 3 0 0 3 3 3 2 Reticulon DUF2870 PF11069.3 CEP10280.1 - 0.14 12.2 0.5 0.28 11.2 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) SNF2_N PF00176.18 CEP10281.1 - 2.5e-79 266.1 1.1 2.5e-79 266.1 0.8 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 CEP10281.1 - 2.9e-23 81.5 2.9 1e-22 79.8 2.0 2.0 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 CEP10281.1 - 2.4e-17 62.5 0.0 1.2e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 CEP10281.1 - 4.4e-08 33.1 0.1 1.6e-07 31.3 0.1 2.0 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 CEP10281.1 - 2.7e-07 29.8 2.0 9.6e-07 28.1 1.4 2.1 1 0 0 1 1 1 1 QLQ DUF1569 PF07606.6 CEP10281.1 - 0.011 15.7 0.5 0.035 14.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) HSA PF07529.8 CEP10281.1 - 0.41 10.4 8.2 0.18 11.5 3.3 2.4 2 0 0 2 2 2 0 HSA Metallophos PF00149.23 CEP10282.1 - 2.2e-43 148.0 0.3 2.7e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cwf21 PF08312.7 CEP10282.1 - 0.038 13.8 1.0 0.067 13.0 0.7 1.4 1 0 0 1 1 1 0 cwf21 domain Trep_Strep PF09605.5 CEP10284.1 - 0.00069 19.3 2.9 0.32 10.6 0.1 2.6 2 0 0 2 2 2 2 Hypothetical bacterial integral membrane protein (Trep_Strep) Spc7_N PF15402.1 CEP10284.1 - 5.1 4.9 13.0 7 4.5 9.0 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 TerB-C PF15615.1 CEP10285.1 - 0.021 15.0 0.2 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 TerB-C domain DUF4238 PF14022.1 CEP10285.1 - 0.053 12.7 0.1 0.055 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Nsp1 PF11501.3 CEP10285.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Non structural protein Nsp1 Fungal_trans PF04082.13 CEP10287.1 - 2.3e-14 52.9 0.1 2.4e-13 49.5 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain PP2C PF00481.16 CEP10288.1 - 1.7e-21 76.8 0.0 2.4e-20 73.0 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CEP10288.1 - 0.00038 19.9 0.0 0.0022 17.4 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PHD PF00628.24 CEP10289.1 - 4.4e-07 29.4 6.9 9.9e-07 28.3 4.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 CEP10289.1 - 0.23 11.7 4.6 0.36 11.0 1.9 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PEX11 PF05648.9 CEP10290.1 - 7.1e-29 100.6 0.0 8.5e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PPR_2 PF13041.1 CEP10291.1 - 2.8e-41 139.2 9.1 1.4e-11 44.1 0.0 10.0 9 2 2 11 11 11 6 PPR repeat family PPR_3 PF13812.1 CEP10291.1 - 2.5e-24 83.4 10.9 2.2e-05 24.3 0.0 12.4 14 0 0 14 14 14 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEP10291.1 - 1.7e-22 78.5 0.9 1e-06 28.1 0.0 8.5 10 0 0 10 10 10 4 PPR repeat PPR PF01535.15 CEP10291.1 - 9.4e-21 72.3 5.5 2.5e-06 27.0 0.0 10.0 12 0 0 12 12 12 5 PPR repeat ECSIT PF06239.6 CEP10291.1 - 0.0014 17.5 1.9 0.47 9.2 0.0 4.0 3 1 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway RNase_P_Rpp14 PF01900.14 CEP10291.1 - 0.023 14.5 0.0 0.082 12.8 0.0 1.9 1 0 0 1 1 1 0 Rpp14/Pop5 family Fucose_iso_C PF02952.12 CEP10291.1 - 0.023 14.1 0.0 4.5 6.7 0.0 2.5 2 0 0 2 2 2 0 L-fucose isomerase, C-terminal domain PMEI PF04043.10 CEP10291.1 - 0.66 9.8 6.7 0.56 10.1 0.2 3.0 2 2 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Mak10 PF04112.8 CEP10292.1 - 4.2e-44 149.7 0.3 1.1e-43 148.3 0.2 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF3449 PF11931.3 CEP10293.1 - 4e-74 248.3 5.8 1.4e-73 246.6 2.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 CEP10293.1 - 8.9e-11 41.1 0.3 2.5e-10 39.6 0.2 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 CEP10293.1 - 1.1e-08 34.9 2.3 5.6e-06 26.3 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP10293.1 - 0.00016 21.7 0.9 0.00016 21.7 0.6 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CEP10293.1 - 0.0004 20.4 0.5 0.0004 20.4 0.3 4.0 4 0 0 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CEP10293.1 - 0.29 11.5 4.3 3.9 8.0 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP10293.1 - 0.94 9.9 4.2 7.5 7.1 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1250 PF06855.7 CEP10293.1 - 4.2 6.9 7.0 1.9 8.0 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1250) DHDPS PF00701.17 CEP10295.1 - 2.7e-48 164.0 0.0 3.1e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Glyco_transf_34 PF05637.7 CEP10296.1 - 4.3e-20 72.2 0.7 1.5e-19 70.5 0.5 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 CEP10296.1 - 4e-09 36.1 0.0 1e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 CEP10296.1 - 6.5e-06 26.0 0.7 0.00044 20.0 0.2 2.4 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase LytTR PF04397.10 CEP10296.1 - 0.085 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 LytTr DNA-binding domain DUF1675 PF07897.6 CEP10296.1 - 0.93 9.3 4.7 1.6 8.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) WD40 PF00400.27 CEP10298.1 - 2.1e-10 40.0 5.3 7.1e-07 28.8 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat CMAS PF02353.15 CEP10299.1 - 4.6e-66 222.6 1.4 5.6e-66 222.4 1.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CEP10299.1 - 1.2e-10 41.2 0.1 2.2e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP10299.1 - 1.7e-10 41.2 0.0 3.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP10299.1 - 1.7e-07 31.6 0.0 3.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP10299.1 - 2.9e-07 30.1 0.0 5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP10299.1 - 1.5e-06 28.4 0.0 4.6e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CEP10299.1 - 1.6e-05 24.3 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CEP10299.1 - 2.6e-05 24.7 0.0 5.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CEP10299.1 - 0.00023 20.5 0.0 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CEP10299.1 - 0.0017 18.4 0.0 0.0049 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEP10299.1 - 0.0062 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CEP10299.1 - 0.072 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Mito_carr PF00153.22 CEP10300.1 - 9.9e-59 195.0 6.7 7.2e-20 70.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.1 CEP10300.1 - 0.015 14.9 0.1 0.55 9.9 0.1 2.4 2 0 0 2 2 2 0 PrcB C-terminal MtrF PF09472.5 CEP10300.1 - 5.9 6.1 6.9 0.44 9.8 0.1 2.6 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) peroxidase PF00141.18 CEP10301.1 - 2e-48 164.8 0.0 2.9e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MotB_plug PF13677.1 CEP10301.1 - 0.018 14.3 0.9 0.46 9.8 0.2 2.3 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB Peptidase_M48 PF01435.13 CEP10302.1 - 5.2e-17 62.1 0.2 1.4e-16 60.7 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M48 TPR_1 PF00515.23 CEP10302.1 - 0.089 12.4 0.3 0.19 11.3 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Auto_anti-p27 PF06677.7 CEP10303.1 - 6.6e-15 54.5 0.9 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Peptidase_M64 PF09471.5 CEP10303.1 - 0.02 14.5 0.6 0.037 13.6 0.2 1.5 1 1 1 2 2 2 0 IgA Peptidase M64 Spatacsin_C PF14649.1 CEP10303.1 - 0.35 9.6 4.5 0.4 9.5 0.4 2.1 2 0 0 2 2 2 0 Spatacsin C-terminus HAUS6_N PF14661.1 CEP10305.1 - 0.028 13.7 0.8 0.043 13.1 0.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RVT_1 PF00078.22 CEP10306.1 - 1.5e-15 57.1 0.1 4.4e-15 55.6 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CEP10306.1 - 6.8e-06 25.7 0.1 1.9e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Dam PF05869.6 CEP10306.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) CagE_TrbE_VirB PF03135.9 CEP10306.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Kinesin-related PF06548.6 CEP10307.1 - 0.0048 15.5 1.8 0.0058 15.2 1.2 1.1 1 0 0 1 1 1 1 Kinesin-related Helitron_like_N PF14214.1 CEP10308.1 - 9.3e-13 48.3 0.0 1.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-H2C2 PF09337.5 CEP10309.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger rve PF00665.21 CEP10311.1 - 9.5e-06 25.7 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CEP10313.1 - 1.2e-05 25.6 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP10313.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.7 CEP10313.1 - 0.025 14.1 0.2 0.048 13.2 0.1 1.5 1 1 0 1 1 1 0 Putative peptidase (DUF1758) HAUS6_N PF14661.1 CEP10314.1 - 0.16 11.2 7.3 0.023 14.0 1.2 1.9 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Cut8_N PF14482.1 CEP10314.1 - 7.6 6.6 9.0 2.2 8.3 1.2 2.7 2 1 0 2 2 2 0 Cut8 proteasome-binding domain NmrA PF05368.8 CEP10316.1 - 2.1e-08 33.6 0.0 1.1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 CEP10316.1 - 2.7e-05 24.2 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CEP10316.1 - 0.055 13.3 1.3 0.1 12.5 0.0 2.1 3 0 0 3 3 3 0 short chain dehydrogenase TPR_11 PF13414.1 CEP10317.1 - 2.1e-18 65.7 4.9 4.7e-18 64.5 3.4 1.6 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CEP10317.1 - 2.5e-12 45.8 3.1 1.6e-07 30.5 0.5 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CEP10317.1 - 1.6e-09 36.9 3.2 0.00013 21.6 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP10317.1 - 3.8e-08 32.9 0.5 2.1e-05 24.3 0.5 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP10317.1 - 1.3e-05 25.0 2.8 2.7e-05 24.0 2.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP10317.1 - 3.1e-05 24.5 1.4 6.2e-05 23.5 0.9 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP10317.1 - 3.7e-05 23.9 0.1 0.057 14.0 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP10317.1 - 4.1e-05 23.8 3.2 0.00013 22.2 1.6 2.4 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP10317.1 - 8.6e-05 22.0 0.7 0.12 12.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP10317.1 - 0.00027 21.0 1.0 0.00062 19.8 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CEP10317.1 - 0.00082 18.9 2.8 0.054 13.2 0.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 CEP10317.1 - 0.016 15.1 5.0 1.2 9.1 0.2 2.8 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 CEP10317.1 - 0.025 14.4 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3446 PF11928.3 CEP10317.1 - 0.027 14.6 0.3 4.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) TPR_10 PF13374.1 CEP10317.1 - 0.074 13.0 0.5 0.67 9.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3602 PF12223.3 CEP10317.1 - 3.7 8.0 5.5 0.43 10.9 0.2 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF3602) zf-CCCH PF00642.19 CEP10318.1 - 2.1e-19 68.7 16.0 2e-10 40.0 1.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) W2 PF02020.13 CEP10318.1 - 1.1e-09 38.1 7.2 1.1e-09 38.1 5.0 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon NUDIX PF00293.23 CEP10318.1 - 3e-09 36.6 0.0 7.6e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain zf-CCCH_2 PF14608.1 CEP10318.1 - 0.051 13.5 10.4 0.58 10.2 0.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF948 PF06103.6 CEP10318.1 - 0.52 10.1 4.2 2.1 8.2 2.9 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Neurochondrin PF05536.6 CEP10319.1 - 1.5e-54 185.2 11.2 1.8e-54 184.9 7.8 1.1 1 0 0 1 1 1 1 Neurochondrin Utp12 PF04003.7 CEP10319.1 - 0.017 14.9 2.9 3.1 7.7 0.0 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family Acyl_transf_3 PF01757.17 CEP10320.1 - 0.045 12.5 11.2 0.014 14.2 3.9 2.0 1 1 0 2 2 2 0 Acyltransferase family DUF3981 PF13139.1 CEP10320.1 - 0.88 9.5 3.1 0.75 9.8 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3981) Aminotran_4 PF01063.14 CEP10321.1 - 4.6e-30 104.7 0.0 7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV TAFII28 PF04719.9 CEP10322.1 - 1.3e-32 111.4 0.1 2.6e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Kei1 PF08552.6 CEP10322.1 - 0.0087 15.7 0.5 0.0087 15.7 0.3 2.8 2 1 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 RasGEF PF00617.14 CEP10323.1 - 5.6e-42 143.5 0.2 1.3e-41 142.4 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain Cwf_Cwc_15 PF04889.7 CEP10323.1 - 7.1 6.2 16.6 0.28 10.8 5.0 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-RVT PF13966.1 CEP10324.1 - 0.079 13.2 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DDE_3 PF13358.1 CEP10325.1 - 1.6e-17 63.6 0.0 2.7e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease APG6 PF04111.7 CEP10326.1 - 2.5 7.0 12.4 0.2 10.6 3.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 MAS20 PF02064.10 CEP10326.1 - 2.8 7.8 7.6 4.1 7.3 0.1 2.8 3 0 0 3 3 3 0 MAS20 protein import receptor HgmA PF04209.8 CEP10327.1 - 3e-191 635.3 0.1 3.4e-191 635.1 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HLH PF00010.21 CEP10328.1 - 1.8e-17 62.7 3.0 4.2e-17 61.5 2.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tubulin PF00091.20 CEP10329.1 - 4.6e-69 232.5 0.0 6.1e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEP10329.1 - 2.1e-50 170.0 0.0 3.1e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CEP10329.1 - 0.00047 19.6 0.0 0.00077 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 CEP10330.1 - 3e-14 52.8 0.0 5.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.25 CEP10330.1 - 1.8e-05 24.4 0.0 3.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Abhydrolase_5 PF12695.2 CEP10330.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zip PF02535.17 CEP10331.1 - 5.5e-19 68.3 20.9 5e-18 65.1 14.0 1.9 1 1 1 2 2 2 1 ZIP Zinc transporter TPT PF03151.11 CEP10332.1 - 1.1e-26 93.3 8.2 1.1e-26 93.3 5.7 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CEP10332.1 - 1.2e-06 27.6 19.4 2e-06 26.9 13.4 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP10332.1 - 1.1e-05 25.5 27.6 4.6e-05 23.4 8.1 2.9 2 1 1 3 3 3 2 EamA-like transporter family GWT1 PF06423.7 CEP10332.1 - 0.3 11.1 8.0 2.1 8.4 0.6 2.8 2 2 0 2 2 2 0 GWT1 Pam17 PF08566.5 CEP10333.1 - 1.1e-56 191.2 0.2 1.4e-56 190.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 EutH PF04346.7 CEP10333.1 - 0.086 11.7 0.8 0.23 10.3 0.6 1.6 1 1 1 2 2 2 0 Ethanolamine utilisation protein, EutH COPI_assoc PF08507.5 CEP10334.1 - 4.3e-32 110.6 14.2 4.9e-32 110.4 9.8 1.0 1 0 0 1 1 1 1 COPI associated protein DUF4179 PF13786.1 CEP10334.1 - 0.058 13.6 4.4 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Myelin_MBP PF01669.12 CEP10334.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Myelin basic protein IncA PF04156.9 CEP10334.1 - 0.8 9.2 9.6 4.7 6.7 0.0 2.1 2 0 0 2 2 2 0 IncA protein DUF2583 PF10762.4 CEP10334.1 - 1 9.5 8.7 1.2 9.3 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) LRR_6 PF13516.1 CEP10335.1 - 0.00016 21.3 4.8 0.017 15.1 0.0 4.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 CEP10335.1 - 0.00098 18.8 1.9 3.8 7.9 0.0 4.9 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 CEP10335.1 - 0.0028 17.5 2.4 13 6.4 0.0 5.1 3 0 0 3 3 3 1 Leucine rich repeat STAS_2 PF13466.1 CEP10335.1 - 0.0065 16.4 0.1 0.026 14.5 0.1 2.1 1 1 1 2 2 2 1 STAS domain LRR_8 PF13855.1 CEP10335.1 - 0.13 12.0 4.2 0.26 11.0 0.1 3.3 3 1 2 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 CEP10335.1 - 1.6 8.4 6.1 6.9 6.4 0.2 4.4 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) HsbA PF12296.3 CEP10336.1 - 1.3e-07 31.5 1.7 1.5e-07 31.3 0.5 1.6 1 1 1 2 2 2 1 Hydrophobic surface binding protein A DUF505 PF04458.7 CEP10336.1 - 0.11 10.6 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) DAO PF01266.19 CEP10337.1 - 3.7e-53 180.7 0.0 4.4e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP10337.1 - 5.8e-07 29.4 0.0 3.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP10337.1 - 2.2e-06 27.7 0.1 0.0046 16.8 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP10337.1 - 2.1e-05 24.3 0.0 0.0094 15.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 CEP10337.1 - 0.00052 19.0 0.0 0.011 14.6 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 CEP10337.1 - 0.0066 15.5 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 CEP10337.1 - 0.017 13.5 0.0 0.69 8.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 CEP10337.1 - 0.036 14.4 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 CEP10337.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 CEP10337.1 - 0.052 12.1 0.1 0.098 11.2 0.0 1.5 1 1 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 CEP10337.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Hydrolase PF00702.21 CEP10337.1 - 0.16 12.3 0.0 2.2 8.6 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DLH PF01738.13 CEP10338.1 - 4.9e-21 75.0 0.0 5.6e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CEP10338.1 - 9.3e-05 22.2 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP10338.1 - 0.0019 18.1 0.1 0.037 13.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP10338.1 - 0.031 13.8 0.0 0.075 12.5 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CEP10338.1 - 0.12 11.8 0.1 2.6 7.5 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold HSP70 PF00012.15 CEP10339.1 - 1e-242 806.4 12.7 1.2e-242 806.2 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP10339.1 - 3.2e-17 62.1 2.4 3.2e-16 58.8 1.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CEP10339.1 - 0.00045 19.8 0.0 0.00092 18.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Asp_decarbox PF02261.11 CEP10339.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Aspartate decarboxylase Hydantoinase_A PF01968.13 CEP10339.1 - 0.045 12.8 3.8 0.33 10.0 0.0 2.7 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase eIF3_N PF09440.5 CEP10339.1 - 0.14 12.3 7.2 0.043 13.9 2.7 1.8 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain GCD14 PF08704.5 CEP10341.1 - 2.1e-15 56.8 0.0 4.5e-15 55.8 0.0 1.5 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 CEP10341.1 - 7.5e-09 36.1 0.0 9.7e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP10341.1 - 2.8e-06 26.9 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CEP10341.1 - 2.7e-05 24.9 0.0 4.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEP10341.1 - 0.00024 20.7 0.0 0.00048 19.7 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CEP10341.1 - 0.00057 19.8 0.0 0.001 19.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP10341.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CEP10341.1 - 0.0028 16.7 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MFS_1 PF07690.11 CEP10342.1 - 3.9e-38 131.0 45.4 3e-36 124.8 17.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CEP10342.1 - 0.014 15.2 8.3 0.074 12.8 0.2 2.9 1 1 1 2 2 2 0 MFS_1 like family LCM PF04072.9 CEP10343.1 - 8.3e-26 90.6 0.0 1.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Seryl_tRNA_N PF02403.17 CEP10344.1 - 1.1 9.3 8.4 0.2 11.6 0.8 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pox_F17 PF04767.7 CEP10344.1 - 1.9 8.7 5.0 2.5 8.4 2.1 2.1 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein Arm PF00514.18 CEP10345.1 - 1.1e-26 91.7 9.8 2.2e-06 27.2 0.0 8.1 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEP10345.1 - 5.7e-19 68.1 4.5 1e-05 25.7 0.2 5.6 2 2 4 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CEP10345.1 - 3.2e-13 49.7 6.2 0.039 14.4 0.0 6.9 6 2 2 8 8 8 5 HEAT-like repeat HEAT PF02985.17 CEP10345.1 - 1.2e-08 34.2 9.8 0.038 14.0 0.0 8.3 9 0 0 9 9 9 1 HEAT repeat RICTOR_V PF14668.1 CEP10345.1 - 0.0019 18.0 0.0 0.45 10.4 0.0 4.0 3 1 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 PUL PF08324.6 CEP10345.1 - 0.056 12.2 0.0 0.26 10.0 0.0 2.0 2 1 1 3 3 3 0 PUL domain IBB PF01749.15 CEP10345.1 - 0.092 12.9 5.0 0.21 11.7 3.5 1.6 1 0 0 1 1 1 0 Importin beta binding domain Pex24p PF06398.6 CEP10346.1 - 5.5e-36 124.0 0.7 7.7e-36 123.6 0.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.17 CEP10346.1 - 1e-10 41.1 5.1 1.7e-10 40.4 3.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4206 PF13901.1 CEP10346.1 - 0.035 13.6 1.7 0.069 12.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) BCAS3 PF12490.3 CEP10346.1 - 0.046 13.0 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Prok-RING_1 PF14446.1 CEP10346.1 - 0.24 11.1 2.9 0.45 10.2 2.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 CEP10346.1 - 0.98 9.1 5.1 2.3 8.0 3.5 1.6 1 0 0 1 1 1 0 PHD-finger Methyltransf_23 PF13489.1 CEP10347.1 - 6.6e-11 42.1 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP10347.1 - 2.5e-07 30.4 0.0 6.4e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP10347.1 - 8.2e-07 29.3 0.0 3.3e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP10347.1 - 8.6e-06 26.1 0.1 5.2e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP10347.1 - 3e-05 24.5 0.1 0.00012 22.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP10347.1 - 0.0043 17.5 0.0 0.019 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CEP10347.1 - 0.0063 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP10347.1 - 0.007 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 CEP10347.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 CEP10347.1 - 0.025 13.7 0.1 0.071 12.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.3 CEP10347.1 - 0.16 10.9 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Motile_Sperm PF00635.21 CEP10348.1 - 2e-24 85.2 1.3 3.9e-24 84.3 0.9 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PapD-like PF14874.1 CEP10348.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like Bystin PF05291.6 CEP10349.1 - 4.8e-68 229.3 0.0 6.3e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF1777 PF08648.7 CEP10350.1 - 6.4e-35 120.5 52.8 1.3e-34 119.5 35.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) AF-4 PF05110.8 CEP10350.1 - 7.2 4.3 19.9 7.8 4.2 13.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF936 PF06075.7 CEP10350.1 - 9.2 5.0 17.8 10 4.9 12.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Pro_isomerase PF00160.16 CEP10351.1 - 2.6e-47 160.9 0.1 4.7e-47 160.0 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CEP10351.1 - 1.5e-13 50.1 0.0 2.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10351.1 - 1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10351.1 - 8.5e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpc4 PF05132.9 CEP10351.1 - 0.023 14.6 3.6 0.91 9.5 1.6 2.2 1 1 1 2 2 2 0 RNA polymerase III RPC4 Aa_trans PF01490.13 CEP10352.1 - 1.8e-60 204.5 30.8 2.6e-60 204.0 21.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_31 PF13847.1 CEP10352.1 - 1.2e-07 31.4 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP10352.1 - 8.4e-07 28.8 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP10352.1 - 8.5e-07 29.3 0.0 2.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP10352.1 - 8.3e-06 24.9 0.0 1.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 CEP10352.1 - 5.3e-05 23.6 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP10352.1 - 7e-05 23.3 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEP10352.1 - 0.0045 16.1 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Arrestin_N PF00339.24 CEP10353.1 - 7.1e-08 32.4 0.0 4.7e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP10353.1 - 1.5e-05 25.0 0.1 0.0035 17.4 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Carmo_coat_C PF08462.5 CEP10353.1 - 0.044 13.6 0.1 0.42 10.5 0.0 2.5 4 0 0 4 4 4 0 Carmovirus coat protein PP2C PF00481.16 CEP10354.1 - 1.2e-43 149.3 0.1 3.4e-42 144.6 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CEP10354.1 - 4.9e-06 26.1 0.0 8.2e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CEP10354.1 - 0.0082 15.8 0.1 0.027 14.1 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Lumazine_bd_2 PF12893.2 CEP10354.1 - 0.0082 16.6 0.1 0.03 14.8 0.1 1.8 2 0 0 2 2 2 1 Putative lumazine-binding DUF3990 PF13151.1 CEP10354.1 - 0.022 14.1 0.1 3.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) EBV-NA1 PF02905.9 CEP10354.1 - 0.069 12.6 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain DXP_synthase_N PF13292.1 CEP10355.1 - 0.0022 16.9 0.1 0.0033 16.4 0.1 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Reo_sigmaC PF04582.7 CEP10355.1 - 0.0063 15.7 0.2 0.011 14.8 0.2 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein MCPsignal PF00015.16 CEP10355.1 - 0.0086 15.6 0.8 0.015 14.8 0.6 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain LOH1CR12 PF10158.4 CEP10355.1 - 0.013 15.3 1.7 0.12 12.2 0.2 2.6 1 1 0 2 2 2 0 Tumour suppressor protein Syntaxin PF00804.20 CEP10355.1 - 0.092 12.9 5.6 0.56 10.3 2.9 3.0 1 1 0 1 1 1 0 Syntaxin Fib_alpha PF08702.5 CEP10355.1 - 0.1 12.7 4.3 0.14 12.2 0.8 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 CEP10355.1 - 0.13 12.5 6.0 0.27 11.5 0.2 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 CEP10355.1 - 0.24 10.9 6.2 0.48 9.9 2.7 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1319 PF07028.6 CEP10355.1 - 0.24 11.6 5.8 0.41 10.8 1.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) DUF1664 PF07889.7 CEP10355.1 - 0.34 10.7 2.7 1 9.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 CEP10355.1 - 0.77 8.6 5.1 1.4 7.8 3.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 CEP10355.1 - 0.9 9.9 8.1 7 7.1 1.5 3.8 2 1 2 4 4 4 0 Syntaxin 6, N-terminal SlyX PF04102.7 CEP10355.1 - 2.4 8.6 6.7 0.74 10.2 0.6 2.8 3 0 0 3 3 2 0 SlyX bZIP_1 PF00170.16 CEP10356.1 - 0.0067 16.3 18.8 0.042 13.8 12.9 2.3 1 1 0 1 1 1 1 bZIP transcription factor DUF1202 PF06717.6 CEP10356.1 - 0.041 13.1 0.2 0.083 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DUF972 PF06156.8 CEP10356.1 - 0.056 13.8 1.0 0.22 11.8 0.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 CEP10356.1 - 0.55 10.0 21.9 0.18 11.6 3.4 3.3 2 1 1 3 3 3 0 Basic region leucine zipper Ribophorin_II PF05817.9 CEP10357.1 - 6e-28 97.4 2.2 6.7e-28 97.2 1.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF2232 PF09991.4 CEP10357.1 - 0.32 9.9 7.1 0.13 11.1 2.7 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Peptidase_C2 PF00648.16 CEP10358.1 - 3.3e-35 121.5 0.0 6.8e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CEP10358.1 - 7.2e-31 106.8 0.1 3.2e-11 43.0 0.0 4.2 3 1 0 3 3 3 3 Calpain large subunit, domain III MIT PF04212.13 CEP10358.1 - 8.3e-16 57.6 9.5 8.5e-08 31.9 1.6 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Aida_N PF08910.5 CEP10358.1 - 0.004 17.3 0.9 0.013 15.6 0.1 2.1 2 0 0 2 2 2 1 Aida N-terminus ADIP PF11559.3 CEP10358.1 - 0.025 14.4 2.6 0.052 13.4 1.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_2 PF07719.12 CEP10358.1 - 0.42 10.6 8.9 0.3 11.1 0.3 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP10358.1 - 0.56 9.9 4.8 1.4 8.6 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP10358.1 - 1.1 9.2 4.1 0.57 10.1 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.10 CEP10358.1 - 1.8 7.7 8.5 3 6.9 5.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GCV_H PF01597.14 CEP10359.1 - 4.7e-45 152.1 0.3 5.6e-45 151.9 0.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CEP10359.1 - 0.00031 20.3 0.9 0.0012 18.4 0.5 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 CEP10359.1 - 0.0016 18.1 0.2 0.0027 17.4 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain MSC PF09402.5 CEP10360.1 - 0.021 13.5 0.4 0.023 13.4 0.3 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain EpsG PF14897.1 CEP10360.1 - 0.062 12.2 1.2 0.077 11.9 0.8 1.0 1 0 0 1 1 1 0 EpsG family DDE_Tnp_4 PF13359.1 CEP10361.1 - 1.1e-17 64.0 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CEP10361.1 - 2.1e-06 27.2 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 CEP10361.1 - 0.00031 20.3 0.5 0.001 18.6 0.0 2.0 2 1 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 CEP10361.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Taeniidae_ag PF05596.6 CEP10361.1 - 0.1 12.4 1.2 7 6.5 0.0 3.3 3 0 0 3 3 3 0 Taeniidae antigen S_layer_C PF05124.7 CEP10361.1 - 0.23 11.0 3.3 0.34 10.5 2.3 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region BAH PF01426.13 CEP10362.1 - 0.0013 18.5 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 BAH domain SAP PF02037.22 CEP10364.1 - 1.6e-14 52.9 1.0 3e-14 52.0 0.7 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 CEP10364.1 - 3.6e-05 23.2 0.3 0.00017 21.0 0.2 2.2 1 1 0 1 1 1 1 HeH/LEM domain Tautomerase PF01361.16 CEP10364.1 - 0.091 12.3 0.6 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 Tautomerase enzyme HD_assoc PF13286.1 CEP10364.1 - 1 9.6 3.5 15 5.8 0.2 3.0 2 1 1 3 3 3 0 Phosphohydrolase-associated domain SOBP PF15279.1 CEP10364.1 - 1.6 9.0 11.0 1.8 8.9 7.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DDE_3 PF13358.1 CEP10365.1 - 5e-25 87.9 0.2 3.3e-24 85.3 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP10365.1 - 6.9e-05 22.9 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP10365.1 - 0.0013 19.5 0.0 0.0035 18.0 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP10365.1 - 0.0069 16.3 0.2 0.051 13.6 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP10365.1 - 0.0092 15.6 0.0 0.087 12.5 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Terminase_5 PF06056.7 CEP10365.1 - 0.018 14.6 0.4 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_17 PF12728.2 CEP10365.1 - 0.065 13.5 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Nrap PF03813.9 CEP10369.1 - 0.14 9.6 0.0 0.18 9.2 0.0 1.1 1 0 0 1 1 1 0 Nrap protein zf-H2C2 PF09337.5 CEP10370.1 - 0.12 11.7 1.3 0.2 11.0 0.3 1.9 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger PLRV_ORF5 PF01690.12 CEP10372.1 - 5.7 5.9 26.9 5.4 6.0 18.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AMP-binding PF00501.23 CEP10373.1 - 2.4e-92 309.5 0.0 3.9e-92 308.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Atx10homo_assoc PF09759.4 CEP10373.1 - 2.4e-33 113.9 1.7 1.6e-32 111.2 0.0 2.5 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 CEP10373.1 - 0.00029 20.5 0.1 0.12 12.2 0.0 3.0 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat AMP-binding_C PF13193.1 CEP10373.1 - 0.0015 19.4 0.0 0.0049 17.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sec2p PF06428.6 CEP10374.1 - 1e-07 31.7 14.6 1e-07 31.7 10.1 2.9 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3275 PF11679.3 CEP10374.1 - 0.0014 18.3 1.1 0.0014 18.3 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3275) CENP-H PF05837.7 CEP10375.1 - 0.0017 18.5 7.9 0.0017 18.5 5.5 3.0 1 1 2 3 3 3 1 Centromere protein H (CENP-H) TroA PF01297.12 CEP10375.1 - 0.0086 15.3 0.2 0.0086 15.3 0.2 1.6 2 0 0 2 2 2 1 Periplasmic solute binding protein family Phage_gp53 PF11246.3 CEP10375.1 - 0.017 14.5 7.2 0.027 13.9 5.0 1.3 1 0 0 1 1 1 0 Base plate wedge protein 53 DivIC PF04977.10 CEP10375.1 - 0.044 13.2 16.0 0.042 13.3 1.5 3.3 2 1 1 3 3 3 0 Septum formation initiator ICAT PF06384.6 CEP10375.1 - 0.054 13.2 0.5 0.054 13.2 0.4 2.0 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT DUF3662 PF12401.3 CEP10375.1 - 0.056 13.5 0.9 0.13 12.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2662) DUF3763 PF12592.3 CEP10375.1 - 2.4 7.8 6.5 4.3 7.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) Fe_hyd_lg_C PF02906.9 CEP10377.1 - 1.7e-86 290.0 0.1 1.6e-72 244.2 0.0 2.3 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain DTW PF03942.10 CEP10377.1 - 6.8e-25 87.4 0.2 1.9e-24 86.0 0.0 1.8 2 0 0 2 2 2 1 DTW domain Fe_hyd_SSU PF02256.12 CEP10377.1 - 2.4e-07 30.6 0.1 2.4e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 Iron hydrogenase small subunit DUF2238 PF09997.4 CEP10377.1 - 0.084 12.2 0.2 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) GCHY-1 PF02649.9 CEP10378.1 - 0.0052 16.0 0.4 0.23 10.7 0.0 2.4 2 0 0 2 2 2 2 Type I GTP cyclohydrolase folE2 DUF3893 PF13032.1 CEP10378.1 - 0.018 15.1 0.2 0.27 11.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3893) DUF3038 PF11237.3 CEP10379.1 - 0.011 15.5 0.2 0.012 15.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Pox_MCEL PF03291.11 CEP10380.1 - 1.6e-84 283.6 0.0 2.2e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 CEP10380.1 - 2.3e-08 33.9 0.0 4.3e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP10380.1 - 1.7e-07 31.7 0.0 2.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP10380.1 - 3.6e-07 30.5 0.0 1.2e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP10380.1 - 8.7e-07 28.6 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP10380.1 - 9.1e-07 29.1 0.0 2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP10380.1 - 1.1e-06 29.0 0.0 2.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP10380.1 - 0.00029 20.2 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 CEP10380.1 - 0.00099 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 CEP10380.1 - 0.0069 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 CEP10380.1 - 0.061 12.6 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PrmA PF06325.8 CEP10380.1 - 0.097 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Asp PF00026.18 CEP10381.1 - 2.7e-110 368.5 0.0 3.3e-110 368.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP10381.1 - 3.3e-09 36.9 0.0 2.2e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP10381.1 - 0.00011 21.8 0.0 0.00042 19.8 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CEP10381.1 - 0.0005 20.5 0.0 0.25 11.8 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease DUF2433 PF10360.4 CEP10382.1 - 5.9e-29 101.0 0.5 1e-28 100.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2407_C PF13373.1 CEP10382.1 - 1.2e-10 41.4 0.4 2.9e-10 40.2 0.3 1.7 1 0 0 1 1 1 1 DUF2407 C-terminal domain RRM_1 PF00076.17 CEP10382.1 - 3.1e-09 36.3 0.0 6.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10382.1 - 4.3e-09 36.2 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2407 PF10302.4 CEP10382.1 - 1.2e-06 28.6 0.0 3.6e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 CEP10382.1 - 0.0045 16.3 0.1 0.0095 15.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Metallophos PF00149.23 CEP10382.1 - 0.021 14.2 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase VHS PF00790.14 CEP10383.1 - 3.8e-42 143.2 0.5 1.1e-41 141.7 0.0 2.1 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 CEP10383.1 - 3.9e-21 74.8 1.0 1.7e-20 72.8 0.7 2.1 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 CEP10383.1 - 2.2e-20 73.1 3.5 2.2e-20 73.1 2.4 2.4 2 1 1 3 3 3 1 Adaptin C-terminal domain Pkinase PF00069.20 CEP10384.1 - 1.8e-37 128.9 0.7 2.3e-37 128.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10384.1 - 1.6e-17 63.4 0.0 2.8e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP10384.1 - 0.00027 20.7 0.1 0.0016 18.2 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CEP10384.1 - 0.018 13.8 0.1 0.027 13.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_L2_C PF03947.13 CEP10385.1 - 2.4e-42 143.7 2.1 2.4e-42 143.7 1.4 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CEP10385.1 - 7.7e-16 57.8 0.1 1.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DJ-1_PfpI PF01965.19 CEP10386.1 - 7.2e-29 100.1 0.0 1.1e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CEP10386.1 - 2e-17 62.9 0.0 2.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 CEP10386.1 - 0.0023 17.4 0.0 0.0058 16.1 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CEP10386.1 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain VWA_2 PF13519.1 CEP10386.1 - 0.031 14.3 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain SNO PF01174.14 CEP10386.1 - 0.035 13.7 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family VWA PF00092.23 CEP10386.1 - 0.049 13.3 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Aminotran_5 PF00266.14 CEP10388.1 - 3.8e-12 45.6 0.0 5.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Zn_clus PF00172.13 CEP10389.1 - 4.3e-11 42.5 11.4 6.8e-11 41.8 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PX PF00787.19 CEP10389.1 - 0.029 14.1 0.0 0.094 12.5 0.0 1.9 2 0 0 2 2 2 0 PX domain EMP24_GP25L PF01105.19 CEP10389.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Muskelin_N PF06588.6 CEP10390.1 - 9.9e-71 237.5 0.9 9.9e-71 237.5 0.6 1.7 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_3 PF13415.1 CEP10390.1 - 4.1e-25 87.3 4.8 3.2e-11 43.0 0.1 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP10390.1 - 2.9e-24 84.5 7.7 2.2e-06 27.3 0.0 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP10390.1 - 8.6e-22 76.3 7.1 1.2e-06 28.4 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CEP10390.1 - 2.8e-18 65.1 14.6 9.9e-07 28.2 0.2 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 CEP10390.1 - 7.9e-18 64.0 4.5 0.00039 20.3 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CEP10390.1 - 3.7e-17 61.3 6.2 2.1e-05 24.1 0.1 6.8 6 0 0 6 6 6 5 Kelch motif F5_F8_type_C PF00754.20 CEP10390.1 - 1.9e-05 24.4 0.0 6.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 F5/8 type C domain UPF0016 PF01169.14 CEP10391.1 - 1.7e-43 146.6 20.0 1.1e-22 79.9 5.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.14 CEP10391.1 - 0.071 12.5 16.5 4.2 6.7 11.4 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF4131 PF13567.1 CEP10391.1 - 0.12 11.7 0.9 6 6.2 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3341 PF11821.3 CEP10391.1 - 0.13 11.7 6.2 0.031 13.7 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) DUF204 PF02659.10 CEP10391.1 - 2.6 8.2 11.2 11 6.2 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF TerC PF03741.11 CEP10391.1 - 4.5 6.6 15.2 0.11 11.9 2.6 2.6 2 1 1 3 3 3 0 Integral membrane protein TerC family WD40 PF00400.27 CEP10392.1 - 1.2e-17 63.0 18.3 8.7e-07 28.5 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat zf-RING_2 PF13639.1 CEP10392.1 - 1.1e-09 37.9 12.4 1.1e-09 37.9 8.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP10392.1 - 7.3e-09 35.1 9.3 7.3e-09 35.1 6.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP10392.1 - 8.3e-09 35.3 12.3 8.3e-09 35.3 8.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP10392.1 - 3.7e-07 29.6 12.9 3.7e-07 29.6 8.9 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP10392.1 - 6.4e-07 29.0 11.8 6.4e-07 29.0 8.2 3.1 3 1 0 3 3 3 1 zinc-RING finger domain U-box PF04564.10 CEP10392.1 - 8.5e-06 25.6 0.0 2.3e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.1 CEP10392.1 - 9.2e-05 22.2 11.8 9.2e-05 22.2 8.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CEP10392.1 - 0.00013 22.0 6.4 0.00013 22.0 4.4 3.7 3 1 0 3 3 3 1 RING-H2 zinc finger zf-RING_6 PF14835.1 CEP10392.1 - 0.00046 19.9 2.2 0.00046 19.9 1.5 2.0 3 0 0 3 3 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CEP10392.1 - 0.00081 19.0 14.5 0.003 17.2 5.8 3.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 CEP10392.1 - 0.002 17.6 7.0 0.01 15.3 5.0 2.2 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain YdjO PF14169.1 CEP10392.1 - 0.031 13.7 1.9 8.7 5.8 0.1 3.5 3 0 0 3 3 3 0 Cold-inducible protein YdjO zinc-ribbons_6 PF07191.7 CEP10392.1 - 0.072 12.8 7.3 0.22 11.3 5.1 1.9 1 0 0 1 1 1 0 zinc-ribbons zf-Apc11 PF12861.2 CEP10392.1 - 0.24 11.2 8.3 0.056 13.2 2.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Histidinol_dh PF00815.15 CEP10394.1 - 3.8e-178 592.3 1.4 7.6e-178 591.3 1.0 1.5 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 CEP10394.1 - 9e-25 86.1 0.1 2.2e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CEP10394.1 - 3.2e-12 46.5 1.3 1.2e-11 44.7 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 CEP10394.1 - 0.0033 17.3 0.9 0.016 15.1 0.2 2.2 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain DDE_3 PF13358.1 CEP10395.1 - 7.4e-12 45.2 0.3 1.2e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_trans_4_4 PF13579.1 CEP10396.1 - 0.035 14.2 0.3 0.049 13.7 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain HTH_23 PF13384.1 CEP10398.1 - 0.00086 18.8 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.13 CEP10398.1 - 0.0014 18.3 0.0 0.0019 17.9 0.0 1.3 1 1 0 1 1 1 1 'Paired box' domain HTH_Tnp_ISL3 PF13542.1 CEP10398.1 - 0.0026 16.9 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 FeoC PF09012.5 CEP10398.1 - 0.0038 16.9 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_28 PF13518.1 CEP10398.1 - 0.0038 17.1 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.1 CEP10398.1 - 0.0071 16.1 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF2660 PF10859.3 CEP10398.1 - 0.017 15.3 0.3 0.021 15.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Bot1p PF12298.3 CEP10398.1 - 0.025 14.5 0.1 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein CENP-B_N PF04218.8 CEP10398.1 - 0.041 13.2 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.1 CEP10398.1 - 0.088 12.9 0.0 1.5 9.0 0.0 1.9 1 1 1 2 2 2 0 Winged helix-turn helix DUF3853 PF12964.2 CEP10398.1 - 0.13 12.1 0.0 2.1 8.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3853) DUF3806 PF12713.2 CEP10399.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) RRXRR PF14239.1 CEP10400.1 - 0.061 12.7 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 RRXRR protein Chromo PF00385.19 CEP10401.1 - 5e-12 45.2 1.9 8.2e-11 41.4 0.3 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CEP10401.1 - 6.5e-11 42.3 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP10401.1 - 0.005 16.2 0.2 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 CEP10401.1 - 0.019 14.6 0.4 0.092 12.4 0.1 2.2 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Neuromodulin_N PF10580.4 CEP10401.1 - 1.9 8.2 4.9 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 Gap junction protein N-terminal region Asp_protease_2 PF13650.1 CEP10402.1 - 4.8e-06 26.9 0.0 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP10402.1 - 0.00094 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CEP10402.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Kinesin-related PF06548.6 CEP10403.1 - 0.0077 14.8 1.2 0.013 14.0 0.9 1.3 1 0 0 1 1 1 1 Kinesin-related Helitron_like_N PF14214.1 CEP10405.1 - 7.3e-28 97.5 0.0 8.5e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_1 PF00078.22 CEP10406.1 - 0.00099 18.5 0.2 0.013 14.8 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_28 PF13518.1 CEP10407.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 CEP10407.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.1 CEP10407.1 - 0.053 13.6 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix TrmB PF01978.14 CEP10407.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB STT3 PF02516.9 CEP10408.1 - 9.1 5.1 7.6 11 4.8 5.3 1.0 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit ADH_zinc_N PF00107.21 CEP10409.1 - 6.4e-22 77.5 0.2 9.7e-22 76.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP10409.1 - 7.9e-10 39.7 0.1 1.8e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP10409.1 - 2.2e-07 30.6 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.1 CEP10409.1 - 0.015 15.5 0.1 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Peptidase_C13 PF01650.13 CEP10409.1 - 0.026 13.8 0.0 0.089 12.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase C13 family AlaDh_PNT_C PF01262.16 CEP10409.1 - 0.047 13.2 0.7 0.11 12.0 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Rad33 PF08730.5 CEP10410.1 - 0.069 12.6 1.1 0.096 12.1 0.5 1.5 1 1 0 1 1 1 0 Rad33 IZUMO PF15005.1 CEP10410.1 - 0.12 12.4 3.5 0.13 12.2 1.1 1.9 1 1 1 2 2 2 0 Izumo sperm-egg fusion YlaC PF10777.4 CEP10410.1 - 0.13 11.8 0.4 7.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Inner membrane protein YlaC DUF1248 PF06852.7 CEP10414.1 - 0.023 14.0 0.1 0.059 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) RVT_1 PF00078.22 CEP10415.1 - 6e-23 81.3 0.5 1.3e-22 80.2 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CEP10415.1 - 0.035 14.0 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease RNase_H PF00075.19 CEP10416.1 - 5.3e-06 26.7 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 RNase H Phage_int_SAM_4 PF13495.1 CEP10416.1 - 0.00026 21.2 0.3 0.0018 18.5 0.2 2.3 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Nup54 PF13874.1 CEP10416.1 - 0.057 13.0 0.7 3.7 7.1 0.1 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DNA_pol_viral_C PF00336.13 CEP10416.1 - 0.075 12.2 0.1 0.16 11.2 0.1 1.6 1 1 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Glyco_hydro_18 PF00704.23 CEP10418.1 - 6.4e-71 239.5 2.4 7.7e-71 239.3 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 CEP10419.1 - 2e-49 168.1 0.0 3.4e-40 137.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10419.1 - 8.2e-17 61.1 0.1 4.3e-12 45.6 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase MFS_1 PF07690.11 CEP10419.1 - 1.8e-08 33.5 16.7 6.7e-06 25.0 1.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.18 CEP10419.1 - 0.075 12.7 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF131 PF01998.12 CEP10419.1 - 0.59 9.5 5.9 2.3 7.6 4.1 2.1 1 0 0 1 1 1 0 Protein of unknown function DUF131 zf-H2C2_2 PF13465.1 CEP10420.1 - 4e-11 42.6 10.6 1.4e-05 25.1 0.1 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP10420.1 - 4e-07 29.9 17.4 0.00016 21.8 1.3 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP10420.1 - 0.00033 20.7 9.3 0.0058 16.8 1.3 3.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP10420.1 - 0.011 15.6 4.0 0.14 12.1 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CEP10420.1 - 0.014 15.0 2.1 0.58 9.8 0.5 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 CEP10420.1 - 0.24 11.6 2.5 0.81 9.9 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CEP10420.1 - 2.5 8.5 7.5 33 4.9 0.1 3.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Lung_7-TM_R PF06814.8 CEP10421.1 - 8.6e-66 221.8 22.2 1.1e-65 221.5 15.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CEP10421.1 - 0.28 10.3 30.0 0.032 13.4 16.1 2.5 1 1 1 2 2 2 0 Rhodopsin-like GPCR transmembrane domain Ribosomal_L35Ae PF01247.13 CEP10422.1 - 1.8e-41 139.8 1.4 2.1e-41 139.6 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CEP10422.1 - 0.0015 18.3 0.1 0.4 10.6 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Aldo_ket_red PF00248.16 CEP10423.1 - 3e-50 170.6 0.0 3.5e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NifU_N PF01592.11 CEP10424.1 - 1.7e-45 154.0 0.2 3.9e-44 149.6 0.1 2.2 1 1 1 2 2 2 1 NifU-like N terminal domain EamA PF00892.15 CEP10424.1 - 0.00049 20.1 22.3 0.00078 19.4 3.4 2.6 2 1 0 2 2 2 2 EamA-like transporter family DDE_3 PF13358.1 CEP10424.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Nuc_sug_transp PF04142.10 CEP10424.1 - 0.0027 16.8 1.4 0.0093 15.0 0.8 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 CEP10424.1 - 0.04 13.5 14.6 0.081 12.5 3.2 2.5 2 0 0 2 2 2 0 Triose-phosphate Transporter family Aldo_ket_red PF00248.16 CEP10425.1 - 1.3e-35 122.6 0.3 7.2e-28 97.2 0.1 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Lipase_GDSL PF00657.17 CEP10426.1 - 1.5e-21 77.3 0.3 1.8e-21 77.0 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP10426.1 - 5.6e-07 29.8 0.0 8.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HNH PF01844.18 CEP10427.1 - 0.00062 19.5 1.2 0.00062 19.5 0.8 2.8 3 1 0 3 3 3 1 HNH endonuclease HNH_2 PF13391.1 CEP10427.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease NapB PF03892.9 CEP10427.1 - 0.45 10.1 2.2 1.3 8.6 1.6 1.8 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) RA PF00788.18 CEP10428.1 - 7.4e-11 42.3 0.0 7.6e-07 29.5 0.0 2.8 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 CEP10428.1 - 0.0098 15.2 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 SH3 domain TUG-UBL1 PF11470.3 CEP10428.1 - 0.011 15.6 0.1 1.9 8.4 0.0 3.5 3 1 0 3 3 3 0 GLUT4 regulating protein TUG SMAP PF15477.1 CEP10429.1 - 3.3e-05 24.0 1.7 3.3e-05 24.0 1.2 3.9 2 1 0 2 2 1 1 Small acidic protein family MIP-T3 PF10243.4 CEP10429.1 - 0.00011 20.8 38.1 0.00012 20.6 26.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 CEP10429.1 - 0.0004 19.8 27.6 0.00068 19.0 19.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CDC45 PF02724.9 CEP10429.1 - 0.0019 16.3 16.4 0.0019 16.3 11.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Ycf1 PF05758.7 CEP10429.1 - 0.0057 14.4 23.6 0.0071 14.1 16.4 1.1 1 0 0 1 1 1 1 Ycf1 GAGA_bind PF06217.7 CEP10429.1 - 0.026 14.4 21.9 0.048 13.6 15.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Vfa1 PF08432.5 CEP10429.1 - 0.47 10.4 39.3 1 9.3 27.2 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LMBR1 PF04791.11 CEP10429.1 - 0.53 8.8 8.9 0.6 8.6 6.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mem_trans PF03547.13 CEP10429.1 - 0.71 8.0 8.3 0.86 7.8 5.7 1.2 1 0 0 1 1 1 0 Membrane transport protein SprA-related PF12118.3 CEP10429.1 - 0.91 8.7 23.8 1.2 8.3 16.5 1.2 1 0 0 1 1 1 0 SprA-related family SOBP PF15279.1 CEP10429.1 - 1.1 9.5 13.5 1.3 9.2 9.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CobN-Mg_chel PF02514.11 CEP10429.1 - 1.2 6.4 8.7 1.5 6.1 6.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase CDC27 PF09507.5 CEP10429.1 - 1.4 8.0 42.6 1.6 7.8 29.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2413 PF10310.4 CEP10429.1 - 1.6 7.4 29.0 2 7.1 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Neur_chan_memb PF02932.11 CEP10429.1 - 2.3 8.0 14.5 3.1 7.6 10.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 CEP10429.1 - 2.3 8.0 29.4 3.5 7.4 20.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BTV_NS2 PF04514.7 CEP10429.1 - 2.7 6.7 25.2 3.6 6.3 17.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Mitofilin PF09731.4 CEP10429.1 - 2.7 6.5 29.3 3.5 6.1 20.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein R_equi_Vir PF05526.6 CEP10429.1 - 3.9 7.0 5.6 9.7 5.7 0.1 2.2 1 1 1 2 2 2 0 Rhodococcus equi virulence-associated protein FAM176 PF14851.1 CEP10429.1 - 4.2 7.0 22.4 1.5 8.4 4.0 2.4 1 1 1 2 2 2 0 FAM176 family SAPS PF04499.10 CEP10429.1 - 5.4 5.5 20.1 6 5.3 14.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ndc1_Nup PF09531.5 CEP10429.1 - 7.3 4.8 13.8 8.5 4.6 9.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mt_ATP-synt_B PF05405.9 CEP10430.1 - 1.5e-47 161.0 8.2 2.2e-47 160.5 5.7 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 CEP10430.1 - 0.023 14.5 2.3 0.042 13.7 1.6 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Hepatitis_core PF00906.15 CEP10430.1 - 0.066 12.8 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Hepatitis core antigen COMPASS-Shg1 PF05205.7 CEP10430.1 - 0.68 10.2 6.7 0.88 9.8 1.3 2.5 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 WD40 PF00400.27 CEP10431.1 - 5.5e-54 178.2 26.2 5.4e-11 41.9 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CEP10431.1 - 1.3e-09 36.7 1.4 0.0011 17.2 0.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CEP10431.1 - 4.3e-07 29.8 0.2 0.0062 16.2 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 CEP10431.1 - 0.019 13.9 0.1 11 4.7 0.0 3.9 1 1 3 5 5 5 0 Protein of unknown function (DUF1513) Hira PF07569.6 CEP10431.1 - 0.12 11.5 0.0 3.8 6.6 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split PQQ_3 PF13570.1 CEP10431.1 - 0.17 12.2 1.8 19 5.7 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain Pkinase PF00069.20 CEP10432.1 - 1.9e-38 132.0 0.0 3.4e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain His_Phos_1 PF00300.17 CEP10432.1 - 9.4e-18 64.8 0.0 2.3e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase_Tyr PF07714.12 CEP10432.1 - 8.2e-13 48.0 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP10432.1 - 1.5e-05 24.8 1.1 0.0095 15.6 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Complex1_LYR_1 PF13232.1 CEP10433.1 - 1.5e-10 41.1 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CEP10433.1 - 1.8e-10 40.4 0.0 2.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 CEP10433.1 - 1.1e-06 29.0 0.0 1.5e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like PGM_PMM_I PF02878.11 CEP10434.1 - 2.1e-41 140.6 0.1 6.2e-41 139.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CEP10434.1 - 1.4e-24 86.4 0.0 4.5e-24 84.7 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CEP10434.1 - 4.4e-11 42.8 0.1 8.2e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CEP10434.1 - 1.9e-05 24.5 0.0 6.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pex24p PF06398.6 CEP10435.1 - 3.2e-18 65.6 8.4 4e-18 65.3 1.0 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin C1_1 PF00130.17 CEP10435.1 - 1.6e-11 43.7 13.4 3.8e-11 42.5 9.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CEP10435.1 - 0.37 10.5 13.7 0.05 13.3 6.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 adh_short PF00106.20 CEP10436.1 - 3.5e-31 108.3 1.7 5.4e-31 107.7 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP10436.1 - 6e-18 65.4 1.4 4.3e-17 62.6 0.0 2.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP10436.1 - 1.6e-10 40.9 0.1 1.6e-10 40.9 0.0 2.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CEP10436.1 - 0.0087 16.0 1.2 0.024 14.6 0.0 2.4 2 0 0 2 2 2 1 NADH(P)-binding STAG PF08514.6 CEP10437.1 - 1.2e-32 112.0 8.9 6e-32 109.8 0.8 4.2 2 1 1 3 3 3 1 STAG domain HEAT PF02985.17 CEP10437.1 - 0.0041 17.0 0.5 9.6 6.5 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat Pex14_N PF04695.8 CEP10440.1 - 2.9e-30 105.0 0.2 2.9e-30 105.0 0.1 4.1 3 2 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 CEP10440.1 - 0.0011 18.7 4.6 0.0011 18.7 3.2 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.7 CEP10440.1 - 0.0041 16.9 8.3 0.0075 16.0 5.7 1.4 1 0 0 1 1 1 1 LXG domain of WXG superfamily PhageMin_Tail PF10145.4 CEP10440.1 - 0.0086 15.7 3.3 0.0086 15.7 2.3 2.6 2 1 0 3 3 3 1 Phage-related minor tail protein PilJ PF13675.1 CEP10440.1 - 0.022 15.0 2.7 0.5 10.7 0.2 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4235 PF14019.1 CEP10440.1 - 0.024 14.4 0.2 0.065 13.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) AAA_13 PF13166.1 CEP10440.1 - 0.031 12.7 5.7 0.045 12.2 4.0 1.1 1 0 0 1 1 1 0 AAA domain TMCO5 PF14992.1 CEP10440.1 - 0.035 13.2 8.7 0.054 12.6 6.0 1.2 1 0 0 1 1 1 0 TMCO5 family DASH_Dad2 PF08654.5 CEP10440.1 - 0.11 12.4 6.4 0.072 13.0 2.7 1.9 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF1664 PF07889.7 CEP10440.1 - 0.35 10.6 7.8 0.77 9.5 4.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) APG6 PF04111.7 CEP10440.1 - 0.48 9.4 12.0 0.73 8.8 8.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CEP10440.1 - 0.55 8.0 3.2 0.82 7.4 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 CEP10440.1 - 0.63 9.7 14.9 0.031 14.0 5.0 2.5 2 1 0 2 2 2 0 Laminin Domain II YlqD PF11068.3 CEP10440.1 - 0.78 9.7 9.6 1.4 8.9 6.6 1.4 1 0 0 1 1 1 0 YlqD protein Flagellar_rod PF05149.7 CEP10440.1 - 1.2 8.3 9.7 3.8 6.6 1.2 2.1 1 1 1 2 2 2 0 Paraflagellar rod protein SNARE PF05739.14 CEP10440.1 - 1.2 8.8 5.5 2.5 7.8 1.1 2.8 1 1 1 2 2 2 0 SNARE domain Tropomyosin PF00261.15 CEP10440.1 - 1.7 7.7 16.5 0.4 9.7 9.3 1.4 2 0 0 2 2 2 0 Tropomyosin DUF4407 PF14362.1 CEP10440.1 - 2 7.3 8.5 3.1 6.6 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.1 CEP10440.1 - 2.1 8.2 11.2 4.2 7.3 6.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Sec20 PF03908.8 CEP10440.1 - 2.3 7.9 6.4 2.3 7.9 2.3 2.3 1 1 2 3 3 3 0 Sec20 Atg14 PF10186.4 CEP10440.1 - 2.7 6.8 8.7 4.4 6.1 6.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 CEP10440.1 - 2.7 7.9 14.1 0.039 13.9 4.0 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein XhlA PF10779.4 CEP10440.1 - 2.8 7.9 11.3 0.52 10.2 0.3 3.0 2 1 0 2 2 2 0 Haemolysin XhlA KaiC PF06745.8 CEP10440.1 - 2.8 6.9 5.4 6 5.9 3.8 1.4 1 1 0 1 1 1 0 KaiC TMPIT PF07851.8 CEP10440.1 - 3.8 6.4 6.9 3.5 6.5 4.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein TBPIP PF07106.8 CEP10440.1 - 5 6.6 13.4 16 4.9 9.3 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 CEP10440.1 - 8 6.1 12.2 3.8 7.1 1.3 3.1 1 1 3 4 4 4 0 Prefoldin subunit IncA PF04156.9 CEP10440.1 - 8.3 5.9 11.9 21 4.6 8.2 1.6 1 1 0 1 1 1 0 IncA protein MOZ_SAS PF01853.13 CEP10441.1 - 4.5e-53 179.3 0.4 3.2e-48 163.4 0.1 2.1 1 1 1 2 2 2 2 MOZ/SAS family Acetyltransf_1 PF00583.19 CEP10441.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CEP10441.1 - 0.0037 16.9 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Actin PF00022.14 CEP10442.1 - 8.1e-62 208.8 0.0 2.7e-32 111.6 0.0 2.3 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CEP10442.1 - 0.014 14.0 0.0 0.31 9.5 0.0 2.5 2 0 0 2 2 2 0 MreB/Mbl protein ATG13 PF10033.4 CEP10443.1 - 2.3e-56 190.8 0.2 2.3e-56 190.8 0.1 2.1 2 0 0 2 2 2 1 Autophagy-related protein 13 AAA_23 PF13476.1 CEP10443.1 - 0.049 13.9 7.9 0.91 9.8 0.4 3.2 3 0 0 3 3 3 0 AAA domain zf-Tim10_DDP PF02953.10 CEP10444.1 - 2e-16 59.0 1.7 2.6e-16 58.6 1.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CEP10444.1 - 0.0015 17.9 3.2 0.044 13.2 2.0 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) MRVI1 PF05781.7 CEP10444.1 - 0.054 11.8 0.1 0.06 11.7 0.1 1.0 1 0 0 1 1 1 0 MRVI1 protein c-SKI_SMAD_bind PF08782.5 CEP10444.1 - 0.092 12.8 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Pox_I6 PF04595.8 CEP10444.1 - 0.14 10.8 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus I6-like family Polysacc_deac_1 PF01522.16 CEP10445.1 - 2.5e-30 104.6 0.1 8.8e-30 102.8 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Rifin_STEVOR PF02009.11 CEP10445.1 - 0.15 11.7 0.8 0.25 10.9 0.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family NPR2 PF06218.6 CEP10446.1 - 3.5e-119 398.2 7.3 1.5e-97 327.0 4.3 2.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 CEP10446.1 - 0.0044 15.6 0.7 0.52 8.7 0.0 2.5 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Afi1 PF07792.7 CEP10446.1 - 0.007 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking RNase_H2-Ydr279 PF09468.5 CEP10447.1 - 8.8e-24 84.2 3.7 1.3e-23 83.6 2.6 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) OrfB_Zn_ribbon PF07282.6 CEP10448.1 - 0.066 12.8 0.6 0.12 12.0 0.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Pro_isomerase PF00160.16 CEP10449.1 - 8e-46 156.0 0.9 8.9e-46 155.9 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Suc_Fer-like PF06999.7 CEP10450.1 - 1.5e-38 133.1 0.0 1.5e-38 133.1 0.0 3.2 3 1 0 3 3 3 1 Sucrase/ferredoxin-like Pterin_4a PF01329.14 CEP10450.1 - 4.5e-30 103.2 0.0 1.4e-29 101.6 0.0 2.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DNA_pol_A_exo1 PF01612.15 CEP10450.1 - 2.9e-12 46.4 0.0 8.7e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease zf-C3HC4_3 PF13920.1 CEP10450.1 - 0.0014 18.2 1.8 0.0014 18.2 1.3 4.1 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.8 CEP10450.1 - 0.017 15.0 34.1 0.039 13.8 23.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 CEP10450.1 - 8.9 5.5 43.0 1.8 7.8 1.7 2.2 2 0 0 2 2 2 0 SprA-related family Med15 PF09606.5 CEP10450.1 - 9.4 4.2 35.9 18 3.3 24.9 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pro_isomerase PF00160.16 CEP10452.1 - 6.4e-33 114.1 0.0 3.8e-32 111.6 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med25_VWA PF11265.3 CEP10453.1 - 1.6e-30 105.8 0.0 5.5e-30 104.0 0.0 1.9 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A APG6 PF04111.7 CEP10453.1 - 0.15 11.1 0.0 0.15 11.1 0.0 5.9 4 3 1 5 5 5 0 Autophagy protein Apg6 2-oxoacid_dh PF00198.18 CEP10454.1 - 2.8e-71 239.4 0.0 4.1e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CEP10454.1 - 4e-17 61.6 0.1 9.6e-17 60.3 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CEP10454.1 - 4e-11 42.3 0.0 8.8e-11 41.2 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Helicase_C_2 PF13307.1 CEP10455.1 - 1.9e-53 180.8 0.1 7.9e-53 178.8 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 CEP10455.1 - 2.3e-46 157.3 0.3 5e-46 156.2 0.2 1.6 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 CEP10455.1 - 3.7e-06 26.5 0.0 0.00042 19.8 0.0 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CEP10455.1 - 0.0004 20.2 3.4 0.0041 16.9 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CEP10455.1 - 0.0035 16.5 0.2 2.5 7.2 0.1 2.7 2 1 0 2 2 2 2 PhoH-like protein Sybindin PF04099.7 CEP10456.1 - 1.7e-23 82.9 0.2 2.6e-23 82.3 0.2 1.2 1 0 0 1 1 1 1 Sybindin-like family Sod_Cu PF00080.15 CEP10456.1 - 0.0011 19.1 0.1 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) L51_S25_CI-B8 PF05047.11 CEP10457.1 - 1.3e-11 44.0 0.1 2.2e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RRM_1 PF00076.17 CEP10458.1 - 1.2e-75 249.0 2.8 2.3e-17 62.3 0.0 6.7 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10458.1 - 1.4e-63 210.8 0.6 1e-13 51.0 0.0 6.2 5 1 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10458.1 - 1.8e-30 104.5 0.0 7.6e-06 25.6 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CEP10458.1 - 4.7e-06 26.2 0.1 0.061 13.0 0.1 5.4 4 1 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 CEP10458.1 - 0.0068 16.1 0.0 1.6 8.5 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif MutL_C PF08676.6 CEP10458.1 - 0.12 12.0 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 MutL C terminal dimerisation domain Sua5_yciO_yrdC PF01300.13 CEP10459.1 - 1.4e-55 187.2 0.0 2.2e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CEP10459.1 - 1.5e-29 102.5 0.0 2.9e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding COPIIcoated_ERV PF07970.7 CEP10460.1 - 2.5e-66 223.4 1.4 3.2e-66 223.1 1.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CEP10460.1 - 4.7e-30 103.4 1.0 1.4e-29 101.8 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Enolase_C PF00113.17 CEP10461.1 - 9.2e-156 517.2 0.1 1.2e-155 516.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CEP10461.1 - 5.4e-56 188.1 0.0 8.6e-56 187.4 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 CEP10461.1 - 0.0016 17.4 0.2 0.0034 16.3 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 CEP10461.1 - 0.0072 16.2 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 Enolase C-terminal domain-like HAUS6_N PF14661.1 CEP10462.1 - 0.1 11.9 4.5 0.25 10.6 0.0 3.0 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus AA_kinase PF00696.23 CEP10463.1 - 5.8e-37 127.5 0.4 1e-36 126.6 0.3 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CEP10463.1 - 4.4e-07 29.5 0.3 1.6e-06 27.7 0.1 2.1 2 0 0 2 2 2 1 PUA domain Nucleotid_trans PF03407.11 CEP10463.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF4611 PF15387.1 CEP10464.1 - 0.72 10.0 19.8 4.5 7.4 2.8 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Mg_trans_NIPA PF05653.9 CEP10465.1 - 1.7e-92 309.6 25.0 2.2e-92 309.2 17.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CEP10465.1 - 1.6e-06 28.1 7.7 1.6e-06 28.1 5.3 3.5 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 CEP10465.1 - 6.3e-06 26.3 4.7 6.3e-06 26.3 3.3 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 CEP10465.1 - 0.0014 17.5 15.3 0.0021 16.9 10.6 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Cofilin_ADF PF00241.15 CEP10466.1 - 1.7e-08 34.4 0.1 4e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.24 CEP10466.1 - 1.3e-06 28.5 0.0 3.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4464 PF14713.1 CEP10466.1 - 0.28 10.5 8.8 0.13 11.6 4.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4464) DUF334 PF03904.8 CEP10466.1 - 1.7 7.9 11.5 2.5 7.3 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF4638 PF15472.1 CEP10466.1 - 5.2 6.5 14.9 0.1 12.1 4.4 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4638) CAP_GLY PF01302.20 CEP10467.1 - 4.2e-19 68.0 0.2 8.9e-19 66.9 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain PNRC PF15365.1 CEP10468.1 - 1.6e-09 37.5 5.7 1.6e-09 37.5 4.0 3.8 3 2 0 3 3 3 1 Proline-rich nuclear receptor coactivator DDE_Tnp_1_7 PF13843.1 CEP10468.1 - 0.51 9.3 5.9 0.7 8.8 4.1 1.2 1 0 0 1 1 1 0 Transposase IS4 HD-ZIP_N PF04618.7 CEP10468.1 - 0.71 10.4 9.5 1.4 9.4 6.6 1.6 1 0 0 1 1 1 0 HD-ZIP protein N terminus Neur_chan_memb PF02932.11 CEP10468.1 - 0.75 9.6 4.5 0.8 9.5 3.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 CEP10468.1 - 0.89 8.9 22.2 1.2 8.5 15.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GKAP PF03359.8 CEP10468.1 - 1.5 8.3 13.1 1.8 8.0 9.0 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Striatin PF08232.7 CEP10468.1 - 1.6 9.0 8.6 2.8 8.2 5.9 1.5 1 0 0 1 1 1 0 Striatin family FAM60A PF15396.1 CEP10468.1 - 2.3 7.8 12.6 3.1 7.4 8.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Ribosomal_S3_C PF00189.15 CEP10469.1 - 1e-13 51.3 0.1 1.9e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CEP10469.1 - 7.4e-13 47.8 0.1 1.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CEP10469.1 - 0.0068 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 RNA_pol_Rpb2_45 PF10385.4 CEP10470.1 - 0.024 14.4 4.7 1.2 8.9 0.1 3.3 1 1 2 3 3 3 0 RNA polymerase beta subunit external 1 domain Cwf_Cwc_15 PF04889.7 CEP10470.1 - 0.18 11.4 10.4 0.3 10.7 7.2 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF904 PF06005.7 CEP10470.1 - 0.24 11.6 5.2 0.64 10.3 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) SMC_Nse1 PF07574.8 CEP10470.1 - 0.46 10.0 7.3 0.77 9.3 4.9 1.3 1 1 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex TSC22 PF01166.13 CEP10470.1 - 0.5 10.3 4.9 2.3 8.2 3.4 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF1421 PF07223.6 CEP10470.1 - 1.7 8.3 8.5 0.18 11.5 2.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1421) DivIC PF04977.10 CEP10470.1 - 1.8 8.1 12.3 2.6 7.5 1.0 2.4 1 1 1 2 2 2 0 Septum formation initiator PBP1_TM PF14812.1 CEP10470.1 - 4.3 7.6 7.0 1.3 9.4 0.1 2.6 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spore_YhaL PF14147.1 CEP10471.1 - 0.17 11.3 0.4 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Sporulation protein YhaL Abhydrolase_6 PF12697.2 CEP10472.1 - 8.2e-28 97.8 0.0 1.1e-27 97.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP10472.1 - 3.7e-13 49.4 0.2 2.2e-12 46.9 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CEP10472.1 - 3.1e-08 33.3 0.1 7.2e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CEP10472.1 - 5.4e-08 32.6 0.0 1.3e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CEP10472.1 - 9.2e-05 21.8 0.2 0.55 9.4 0.0 2.9 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 CEP10472.1 - 0.0026 17.6 0.0 0.007 16.2 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Lipase_3 PF01764.20 CEP10472.1 - 0.013 15.0 0.0 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) DUF1100 PF06500.6 CEP10472.1 - 0.023 13.3 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.7 CEP10472.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.6 CEP10472.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Acetyltransf_1 PF00583.19 CEP10473.1 - 7.2e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP10473.1 - 0.00012 22.1 0.1 0.00021 21.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP10473.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF3958 PF13125.1 CEP10473.1 - 0.0059 16.4 0.4 0.022 14.6 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3958) TPR_11 PF13414.1 CEP10474.1 - 1.2e-17 63.2 0.2 2.1e-11 43.2 0.1 2.1 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CEP10474.1 - 2.4e-12 45.7 0.1 0.00017 21.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP10474.1 - 4.4e-12 45.0 0.0 0.00025 20.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP10474.1 - 6.1e-05 22.5 0.0 0.018 14.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP10474.1 - 0.00035 20.1 0.4 1.5 8.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP10474.1 - 0.00045 20.6 0.1 0.025 15.1 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP10474.1 - 0.00057 20.4 0.9 0.14 12.9 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP10474.1 - 0.0014 18.5 0.7 2.4 8.1 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP10474.1 - 0.0028 17.9 0.0 0.049 13.9 0.0 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 CEP10474.1 - 0.004 16.9 0.2 0.055 13.2 0.1 2.1 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_9 PF13371.1 CEP10474.1 - 0.027 14.2 0.0 0.067 13.0 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.5 CEP10474.1 - 0.028 13.4 0.0 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.1 CEP10474.1 - 0.15 12.5 0.2 17 6.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Nsp1_C PF05064.8 CEP10475.1 - 2.5e-35 120.6 10.8 2.5e-35 120.6 7.5 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CEP10475.1 - 2.1 8.5 176.7 0.22 11.7 40.7 5.4 1 1 3 4 4 4 0 Nucleoporin FG repeat region Med9 PF07544.8 CEP10476.1 - 1.5e-06 27.8 0.3 1.9e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF932 PF06067.6 CEP10476.1 - 0.088 12.0 0.2 0.11 11.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF2076 PF09849.4 CEP10479.1 - 0.069 13.1 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4559 PF15112.1 CEP10480.1 - 0.054 12.6 0.1 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DDE_3 PF13358.1 CEP10482.1 - 1.2e-26 93.2 0.0 1.4e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP10482.1 - 0.0092 15.1 0.0 1.4 8.0 0.0 2.0 2 0 0 2 2 2 2 DDE superfamily endonuclease rve PF00665.21 CEP10482.1 - 0.01 15.9 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Dam PF05869.6 CEP10483.1 - 4.5e-05 22.9 0.0 7.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) CENP-F_leu_zip PF10473.4 CEP10486.1 - 0.00074 19.3 5.7 0.0011 18.8 3.9 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.1 CEP10486.1 - 0.01 15.8 4.8 0.017 15.1 3.3 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 CEP10486.1 - 0.073 12.1 7.2 0.084 11.9 5.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 COMP PF11598.3 CEP10486.1 - 0.076 13.0 1.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Phage_GP20 PF06810.6 CEP10486.1 - 0.086 12.2 7.4 0.12 11.7 5.1 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Spc7 PF08317.6 CEP10486.1 - 0.19 10.3 7.5 0.19 10.3 4.8 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 CEP10486.1 - 0.35 10.5 5.7 1.5 8.5 3.7 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4078 PF13300.1 CEP10486.1 - 0.36 10.9 3.7 0.65 10.1 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) Spectrin PF00435.16 CEP10486.1 - 0.48 10.7 5.0 0.5 10.6 1.8 2.0 1 1 1 2 2 2 0 Spectrin repeat ADIP PF11559.3 CEP10486.1 - 0.56 10.1 9.2 0.45 10.4 5.5 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CEP10486.1 - 0.59 9.6 7.3 0.86 9.1 5.1 1.3 1 0 0 1 1 1 0 IncA protein DUF2992 PF11208.3 CEP10486.1 - 2.8 7.8 8.1 0.53 10.1 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Seryl_tRNA_N PF02403.17 CEP10486.1 - 3 7.8 11.0 1.8 8.6 4.0 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 CEP10486.1 - 3.3 7.8 6.1 8.4 6.5 3.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 CEP10486.1 - 3.4 7.4 7.3 17 5.1 5.0 2.0 1 1 0 1 1 1 0 Laminin Domain II Rep_4 PF05797.6 CEP10487.1 - 0.033 12.8 0.4 0.036 12.7 0.3 1.0 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) YqzL PF14006.1 CEP10487.1 - 0.12 12.5 0.3 0.3 11.3 0.1 1.7 2 1 0 2 2 2 0 YqzL-like protein VirE2 PF07229.7 CEP10487.1 - 0.17 10.2 4.8 0.2 10.0 3.3 1.0 1 0 0 1 1 1 0 VirE2 WD40 PF00400.27 CEP10488.1 - 0.0086 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 WD domain, G-beta repeat DDE_3 PF13358.1 CEP10489.1 - 9.4e-07 28.6 0.0 2.1e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP10489.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 CEP10489.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain rve PF00665.21 CEP10491.1 - 9.8e-24 83.7 0.0 2e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP10491.1 - 0.0015 18.0 0.0 0.004 16.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP10491.1 - 0.029 13.7 0.2 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Vault PF01505.13 CEP10491.1 - 0.084 12.9 0.1 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Major Vault Protein repeat ESX-1_EspG PF14011.1 CEP10492.1 - 0.042 13.1 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 EspG family NMU PF02070.10 CEP10492.1 - 2.2 7.8 4.4 6.1 6.4 0.2 2.7 2 1 0 2 2 2 0 Neuromedin U DSS1_SEM1 PF05160.8 CEP10492.1 - 3.2 7.6 7.3 12 5.7 0.2 2.2 2 0 0 2 2 2 0 DSS1/SEM1 family Asp_protease_2 PF13650.1 CEP10493.1 - 0.00012 22.5 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP10493.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CLPTM1 PF05602.7 CEP10493.1 - 0.044 12.4 0.2 0.073 11.7 0.1 1.3 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) HrcA_DNA-bdg PF03444.10 CEP10494.1 - 0.088 12.2 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DNA_pol_phi PF04931.8 CEP10495.1 - 7.2 4.2 7.3 9.3 3.8 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Orn_Arg_deC_N PF02784.11 CEP10496.1 - 4.3e-67 225.9 0.0 5.4e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CEP10496.1 - 2.6e-32 110.9 0.0 5e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 CEP10496.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel polyprenyl_synt PF00348.12 CEP10497.1 - 1.2e-51 175.0 0.1 6.9e-49 166.0 0.0 2.4 3 0 0 3 3 3 2 Polyprenyl synthetase Kelch_4 PF13418.1 CEP10498.1 - 1.9e-23 81.9 14.1 1.7e-06 27.6 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP10498.1 - 2.5e-20 71.7 14.3 5.4e-06 26.3 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_1 PF01344.20 CEP10498.1 - 2.1e-19 68.7 9.9 1.3e-06 27.7 0.0 6.5 6 2 1 7 7 7 3 Kelch motif Kelch_2 PF07646.10 CEP10498.1 - 3.7e-19 67.6 0.7 2.5e-05 23.8 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 CEP10498.1 - 3.8e-19 68.3 13.8 9.6e-06 25.6 0.0 6.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP10498.1 - 5.3e-13 48.6 4.0 0.046 13.6 0.0 6.7 6 0 0 6 6 6 3 Kelch motif YqhR PF11085.3 CEP10498.1 - 0.0048 16.4 3.9 0.015 14.8 0.2 2.4 2 0 0 2 2 2 1 Conserved membrane protein YqhR Secretin PF00263.16 CEP10498.1 - 0.033 13.5 0.4 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial type II and III secretion system protein DUF4271 PF14093.1 CEP10498.1 - 4.4 6.9 8.6 0.1 12.2 0.9 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) RtcR PF06956.6 CEP10500.1 - 0.048 12.9 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Img2 PF05046.9 CEP10501.1 - 1.7e-22 79.4 0.1 2.2e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 CEP10501.1 - 0.0011 18.7 0.1 0.0015 18.2 0.1 1.3 1 1 0 1 1 1 1 Translation initiation factor SUI1 ORC3_N PF07034.6 CEP10502.1 - 1.7e-63 214.5 0.6 1.7e-63 214.5 0.4 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF2419 PF10343.4 CEP10503.1 - 2.1e-119 398.0 0.2 2.4e-119 397.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) E1-E2_ATPase PF00122.15 CEP10504.1 - 5.7e-59 198.9 0.6 5.7e-59 198.9 0.4 2.7 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CEP10504.1 - 2.7e-22 80.2 0.0 5.8e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP10504.1 - 5.8e-15 54.5 0.1 1.5e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEP10504.1 - 1.5e-11 44.8 0.1 3.4e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP10504.1 - 0.00011 21.8 1.3 0.00017 21.2 0.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP10504.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Metallophos PF00149.23 CEP10505.1 - 7.6e-07 28.7 0.4 1.7e-06 27.6 0.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Syntaxin_2 PF14523.1 CEP10506.1 - 1.2e-24 86.2 5.2 1.2e-24 86.2 3.6 2.5 2 1 1 3 3 3 1 Syntaxin-like protein SNARE PF05739.14 CEP10506.1 - 7.7e-08 31.9 2.1 7.7e-08 31.9 1.5 3.0 2 1 0 2 2 2 1 SNARE domain ATP-synt_F6 PF05511.6 CEP10506.1 - 1.3 8.9 7.8 1 9.3 2.2 2.4 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF501 PF04417.7 CEP10506.1 - 1.5 8.6 5.4 2.1 8.2 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) TMPIT PF07851.8 CEP10506.1 - 1.8 7.5 7.6 3.4 6.6 5.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein Prominin PF05478.6 CEP10506.1 - 1.9 5.9 9.0 2.9 5.2 6.3 1.4 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.7 CEP10506.1 - 2.4 7.9 11.2 2.5 7.9 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fumble PF03630.9 CEP10507.1 - 8.3e-127 422.7 2.2 2.8e-125 417.7 1.5 2.0 1 1 0 1 1 1 1 Fumble DUF2097 PF09870.4 CEP10507.1 - 0.096 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) Peptidase_S10 PF00450.17 CEP10508.1 - 6.4e-62 210.0 0.2 8e-62 209.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Adaptin_N PF01602.15 CEP10509.1 - 2e-146 488.4 5.9 2.4e-146 488.1 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CEP10509.1 - 7.5e-23 81.0 1.1 1.8e-22 79.7 0.8 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CEP10509.1 - 4.5e-05 23.6 0.3 0.49 10.7 0.0 4.8 3 3 1 4 4 4 1 HEAT repeats SPG48 PF14764.1 CEP10509.1 - 0.0016 17.0 0.2 0.005 15.3 0.1 1.9 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking Cnd1 PF12717.2 CEP10509.1 - 0.029 14.2 2.3 1.2 8.9 0.1 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 CEP10509.1 - 0.046 13.3 0.8 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) 4HBT PF03061.17 CEP10510.1 - 4.6e-13 49.0 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Whi5 PF08528.6 CEP10510.1 - 0.0013 18.3 0.0 0.0029 17.1 0.0 1.7 1 0 0 1 1 1 1 Whi5 like DUF914 PF06027.7 CEP10511.1 - 1.7e-102 342.7 19.8 2.1e-102 342.4 13.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 CEP10511.1 - 6.3e-07 29.4 29.7 3.8e-06 26.9 4.3 2.9 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 CEP10511.1 - 0.0017 18.0 20.8 0.0055 16.3 0.2 2.5 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 CEP10511.1 - 0.13 11.1 22.4 0.9 8.3 15.5 2.1 1 1 0 1 1 1 0 UAA transporter family TBP PF00352.16 CEP10512.1 - 2.3e-70 231.9 0.1 7.3e-35 118.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CEP10512.1 - 0.00022 21.1 0.1 0.66 10.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) PX PF00787.19 CEP10513.1 - 7.9e-15 54.6 0.2 1.5e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 CEP10513.1 - 1.9e-12 46.6 4.2 4.6e-12 45.4 2.9 1.7 1 0 0 1 1 1 1 SNARE domain PP2C PF00481.16 CEP10514.1 - 5e-70 235.8 0.1 5.7e-70 235.6 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CEP10514.1 - 3.4e-06 26.6 0.0 4.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CEP10514.1 - 0.013 15.1 0.3 0.086 12.5 0.2 2.1 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) DUF3318 PF11780.3 CEP10515.1 - 0.03 13.8 0.3 0.057 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) NuA4 PF09340.5 CEP10516.1 - 4e-25 87.2 0.1 4e-25 87.2 0.1 2.3 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 TFIIA PF03153.8 CEP10516.1 - 0.15 11.9 16.3 0.21 11.4 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 CEP10516.1 - 0.37 9.9 28.2 0.59 9.3 19.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NAD_binding_4 PF07993.7 CEP10517.1 - 3.8e-46 157.0 0.0 6.2e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.14 CEP10517.1 - 4.4e-08 33.2 0.1 2e-07 31.1 0.0 2.2 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.16 CEP10517.1 - 1.8e-05 24.1 0.0 4.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Epimerase PF01370.16 CEP10517.1 - 6e-05 22.5 0.6 0.00044 19.7 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEP10517.1 - 0.099 11.3 0.7 4.8 5.8 0.0 2.6 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family CsbD PF05532.7 CEP10518.1 - 0.0063 16.1 1.3 0.017 14.8 0.9 1.7 1 0 0 1 1 1 1 CsbD-like Mito_carr PF00153.22 CEP10519.1 - 3.2e-23 81.2 0.1 7.9e-10 38.3 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Vert_IL3-reg_TF PF06529.6 CEP10520.1 - 0.055 12.4 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor Dr_adhesin PF12393.3 CEP10520.1 - 0.45 10.6 3.7 1.4 9.0 2.5 1.9 1 0 0 1 1 1 0 Dr family adhesin CP2 PF04516.10 CEP10522.1 - 3.1e-56 190.0 0.2 3.1e-56 190.0 0.1 2.2 2 0 0 2 2 2 1 CP2 transcription factor Lactamase_B PF00753.22 CEP10522.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF755 PF05501.6 CEP10522.1 - 2.3 8.3 38.5 0.27 11.2 6.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF2009 PF09418.5 CEP10523.1 - 1.3e-191 637.3 0.4 1.9e-191 636.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CEP10523.1 - 3.5e-05 23.5 7.9 3.5e-05 23.5 5.5 2.3 2 0 0 2 2 2 1 B-box zinc finger IBR PF01485.16 CEP10523.1 - 0.079 12.8 6.4 0.28 11.0 4.5 1.9 1 0 0 1 1 1 0 IBR domain NOB1_Zn_bind PF08772.6 CEP10523.1 - 0.71 9.7 4.4 1.8 8.4 3.0 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-met PF12874.2 CEP10524.1 - 8.3e-10 38.5 54.2 0.0052 16.9 0.3 8.4 9 0 0 9 9 9 6 Zinc-finger of C2H2 type GBP_repeat PF02526.9 CEP10524.1 - 0.078 12.3 1.9 1.8 8.0 0.0 3.5 3 0 0 3 3 3 0 Glycophorin-binding protein zf-C2H2_2 PF12756.2 CEP10524.1 - 0.092 12.8 40.7 0.58 10.3 1.6 7.5 2 2 6 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CEP10524.1 - 0.35 11.0 67.2 0.12 12.5 2.4 7.7 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding PIF1 PF05970.9 CEP10525.1 - 1.2e-21 77.1 0.1 8.3e-15 54.5 0.0 2.0 2 0 0 2 2 2 2 PIF1-like helicase p450 PF00067.17 CEP10526.1 - 6.5e-73 245.8 0.1 8.6e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 CEP10527.1 - 3e-67 220.2 13.0 1.8e-10 40.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CEP10527.1 - 2.7e-10 40.2 2.8 1.5e-06 28.2 0.3 2.3 2 0 0 2 2 2 2 Tup N-terminal Nbas_N PF15492.1 CEP10527.1 - 0.0025 16.9 0.0 2 7.4 0.0 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 CEP10527.1 - 0.008 14.3 2.6 2.2 6.3 0.1 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 CEP10527.1 - 0.012 15.2 0.2 2.3 7.9 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF605 PF04652.11 CEP10527.1 - 0.54 9.6 15.0 0.77 9.0 10.4 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CEP10527.1 - 1.1 7.3 20.9 1.5 7.0 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chorismate_bind PF00425.13 CEP10528.1 - 5e-83 278.3 0.0 2.1e-82 276.3 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 CEP10528.1 - 6e-35 120.4 0.0 1.6e-24 86.4 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CEP10528.1 - 6.4e-14 52.1 0.2 3.3e-12 46.6 0.1 2.7 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CEP10528.1 - 0.00016 21.1 0.1 0.001 18.5 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 Vfa1 PF08432.5 CEP10530.1 - 8.2e-25 87.8 9.2 1.1e-23 84.2 6.4 2.0 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.3 CEP10530.1 - 0.012 14.2 5.1 0.015 13.9 3.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 CEP10530.1 - 0.017 13.1 6.9 0.018 12.9 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 CEP10530.1 - 0.047 13.0 10.0 0.083 12.2 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 CEP10530.1 - 0.58 8.1 10.6 0.66 7.9 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NST1 PF13945.1 CEP10530.1 - 0.79 9.7 12.0 1.3 9.0 8.3 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Sporozoite_P67 PF05642.6 CEP10530.1 - 1.3 6.8 11.1 1.7 6.4 7.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Menin PF05053.8 CEP10530.1 - 1.4 7.0 7.2 1.6 6.7 5.0 1.1 1 0 0 1 1 1 0 Menin TraH_2 PF06871.6 CEP10530.1 - 1.4 8.3 3.8 2.1 7.7 2.7 1.2 1 0 0 1 1 1 0 TraH_2 FAM176 PF14851.1 CEP10530.1 - 1.5 8.5 4.2 2.9 7.5 2.9 1.5 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.1 CEP10530.1 - 5.2 7.0 13.4 0.14 12.2 4.8 1.7 2 0 0 2 2 2 0 YqfQ-like protein NOA36 PF06524.7 CEP10530.1 - 5.9 6.0 11.2 2.9 7.0 6.3 1.5 2 0 0 2 2 2 0 NOA36 protein DUF4551 PF15087.1 CEP10530.1 - 5.9 5.1 10.0 7.1 4.8 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NPR3 PF03666.8 CEP10530.1 - 6.3 5.2 10.2 8.7 4.7 7.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ribosomal_L34e PF01199.13 CEP10531.1 - 3.6e-41 139.2 5.8 4.5e-41 138.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e GFA PF04828.9 CEP10531.1 - 0.16 11.8 0.8 0.41 10.6 0.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 CEP10531.1 - 1.3 9.3 5.3 0.34 11.1 0.9 2.1 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Mu-like_Com PF10122.4 CEP10531.1 - 10 5.2 8.0 2.7 7.1 0.1 2.7 3 0 0 3 3 3 0 Mu-like prophage protein Com DUF4191 PF13829.1 CEP10532.1 - 0.24 10.4 4.6 9.6 5.2 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) OST3_OST6 PF04756.8 CEP10532.1 - 0.45 10.0 11.4 0.076 12.5 1.2 3.4 2 1 0 3 3 3 0 OST3 / OST6 family DUF2207 PF09972.4 CEP10532.1 - 0.47 8.9 1.6 0.79 8.2 1.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RIC1 PF07064.8 CEP10533.1 - 3.1e-69 233.2 0.4 5.2e-69 232.5 0.3 1.3 1 0 0 1 1 1 1 RIC1 Apc4_WD40 PF12894.2 CEP10533.1 - 0.03 13.8 0.0 4.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CorA PF01544.13 CEP10534.1 - 1e-44 152.7 0.3 1.5e-44 152.1 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Transpos_assoc PF13963.1 CEP10536.1 - 1.5 8.8 9.7 0.22 11.5 0.7 2.5 3 0 0 3 3 3 0 Transposase-associated domain zf-C2H2_2 PF12756.2 CEP10536.1 - 2.5 8.2 10.4 4.8 7.3 0.4 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) COX5B PF01215.14 CEP10537.1 - 1.2e-38 131.8 0.0 1.5e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 CEP10537.1 - 0.0037 16.7 0.5 0.56 9.7 0.0 2.3 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zf-CHCC PF10276.4 CEP10537.1 - 0.008 15.9 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain COG6 PF06419.6 CEP10537.1 - 0.11 10.6 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Med9 PF07544.8 CEP10538.1 - 0.002 17.8 2.3 0.002 17.8 1.6 5.8 5 2 1 6 6 6 1 RNA polymerase II transcription mediator complex subunit 9 HSP9_HSP12 PF04119.7 CEP10538.1 - 0.0022 18.0 0.2 0.025 14.6 0.0 3.0 3 0 0 3 3 3 1 Heat shock protein 9/12 AIP3 PF03915.8 CEP10538.1 - 0.0038 16.2 11.7 0.0038 16.2 8.1 3.8 1 1 3 4 4 4 1 Actin interacting protein 3 DUF3618 PF12277.3 CEP10538.1 - 0.033 14.2 4.5 2 8.5 0.7 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3618) DUF2203 PF09969.4 CEP10538.1 - 2.2 8.5 24.1 2.5 8.3 1.2 5.1 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) NPL4 PF05021.10 CEP10539.1 - 5.3e-103 344.3 0.0 7e-103 343.9 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CEP10539.1 - 3.6e-66 221.3 0.2 6.6e-66 220.4 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CEP10539.1 - 5e-11 42.7 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PB1 PF00564.19 CEP10539.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 PB1 domain Tubulin PF00091.20 CEP10539.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Sec7 PF01369.15 CEP10540.1 - 1.6e-41 142.0 3.5 3.5e-41 140.9 0.3 2.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 CEP10540.1 - 8.2e-32 109.8 0.3 4.1e-31 107.6 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEP10540.1 - 0.0004 20.5 0.0 0.003 17.7 0.0 2.6 1 0 0 1 1 1 1 PH domain adh_short PF00106.20 CEP10541.1 - 1.1e-18 67.7 0.0 2.1e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP10541.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP10541.1 - 3.2e-05 23.6 0.0 7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CEP10541.1 - 5.3e-05 22.7 0.0 7.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.4 CEP10541.1 - 0.038 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain 2-Hacid_dh_C PF02826.14 CEP10541.1 - 0.091 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 CEP10542.1 - 1.5e-15 57.3 0.0 3.2e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP10542.1 - 5e-14 52.5 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP10542.1 - 2.1e-13 50.1 0.0 7.1e-13 48.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP10542.1 - 2.3e-09 37.4 0.0 6.8e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP10542.1 - 2.7e-09 37.3 0.0 8.4e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP10542.1 - 1.4e-08 35.3 0.0 1.1e-07 32.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP10542.1 - 2e-07 30.2 0.0 8.1e-06 25.0 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 CEP10542.1 - 4.1e-05 23.6 0.0 9.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP10542.1 - 0.00025 20.2 0.0 0.00066 18.8 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 CEP10542.1 - 0.0057 15.9 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.11 CEP10542.1 - 0.009 14.3 0.0 0.015 13.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.9 CEP10542.1 - 0.026 13.6 0.0 5.7 6.0 0.0 3.3 3 1 1 4 4 4 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.13 CEP10542.1 - 0.049 12.8 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 CEP10542.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 CEP10542.1 - 0.067 12.8 0.0 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Glycos_transf_1 PF00534.15 CEP10543.1 - 2e-21 76.1 0.0 6e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CEP10543.1 - 1.2e-08 35.2 0.0 1.1e-07 32.0 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CEP10543.1 - 2.2e-06 27.8 0.0 5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4094 PF13334.1 CEP10544.1 - 1.7 9.0 5.8 2.6 8.4 0.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) G6PD_C PF02781.11 CEP10545.1 - 6.2e-121 402.7 0.0 8.7e-121 402.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CEP10545.1 - 5.8e-57 192.8 0.1 2.4e-48 164.8 0.0 2.6 2 0 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, NAD binding domain TLD PF07534.11 CEP10546.1 - 3.7e-41 140.3 0.1 4.3e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 TLD CoA_transf_3 PF02515.12 CEP10547.1 - 2e-54 183.7 0.0 3e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III tRNA_anti-codon PF01336.20 CEP10548.1 - 0.036 13.9 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain GPI-anchored PF10342.4 CEP10549.1 - 4.8e-06 26.9 1.2 4.8e-06 26.9 0.9 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.20 CEP10550.1 - 6.7e-67 225.3 0.0 1.3e-66 224.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10550.1 - 5.1e-41 140.4 0.0 8.8e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP10550.1 - 1.8e-07 30.4 0.0 3.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP10550.1 - 0.00031 19.8 0.0 0.00062 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Reductase_C PF14759.1 CEP10550.1 - 0.01 16.1 0.1 0.42 10.9 0.0 2.6 2 0 0 2 2 2 1 Reductase C-terminal APH PF01636.18 CEP10550.1 - 0.012 15.3 0.8 0.17 11.6 0.5 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family CotH PF08757.6 CEP10551.1 - 8.3e-43 146.8 2.8 1.2e-42 146.3 1.9 1.2 1 0 0 1 1 1 1 CotH protein NAP PF00956.13 CEP10551.1 - 0.062 12.4 0.2 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) ESAG1 PF03238.8 CEP10551.1 - 0.15 11.3 0.4 0.9 8.7 0.1 2.1 2 0 0 2 2 2 0 ESAG protein NAD_kinase PF01513.16 CEP10554.1 - 3.5e-68 229.4 0.0 4.4e-39 133.9 0.0 2.1 2 0 0 2 2 2 2 ATP-NAD kinase DUF3832 PF12909.2 CEP10555.1 - 0.033 14.2 0.7 0.056 13.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3832) zf-RVT PF13966.1 CEP10556.1 - 1.7e-07 31.4 1.6 3.2e-07 30.5 1.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Glyco_hydro_17 PF00332.13 CEP10557.1 - 8.1e-08 31.6 7.4 4.9e-07 29.0 0.2 2.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 RGS PF00615.14 CEP10558.1 - 3.2e-12 46.5 5.1 7.3e-12 45.4 3.6 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain NAS PF03059.11 CEP10559.1 - 1.2e-05 24.5 0.0 1.2e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Pkinase PF00069.20 CEP10560.1 - 7.7e-55 185.8 0.0 1.3e-54 185.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10560.1 - 2.3e-26 92.4 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP10560.1 - 4.8e-05 22.4 0.0 7.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP10560.1 - 0.00093 18.9 1.2 0.0017 18.1 0.9 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CEP10560.1 - 0.0011 18.0 0.6 0.0022 17.1 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NAS PF03059.11 CEP10560.1 - 0.0047 16.1 0.1 0.0091 15.1 0.1 1.4 1 0 0 1 1 1 1 Nicotianamine synthase protein Chorion_2 PF03964.10 CEP10560.1 - 0.026 15.0 1.7 0.067 13.7 1.2 1.7 1 0 0 1 1 1 0 Chorion family 2 YrbL-PhoP_reg PF10707.4 CEP10560.1 - 0.079 12.2 0.2 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ATP-synt_10 PF05176.9 CEP10561.1 - 1.3e-60 204.7 0.2 1.6e-60 204.5 0.2 1.0 1 0 0 1 1 1 1 ATP10 protein TMF_TATA_bd PF12325.3 CEP10562.1 - 5.2e-32 110.1 15.8 5.2e-32 110.1 11.0 7.7 2 1 4 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CEP10562.1 - 8.9e-15 54.2 18.3 8.9e-15 54.2 12.7 11.5 4 3 7 11 11 11 2 TATA element modulatory factor 1 DNA binding Feld-I_B PF09252.5 CEP10562.1 - 0.074 12.9 2.4 1.5 8.7 0.2 3.2 2 0 0 2 2 2 0 Allergen Fel d I-B chain ADK PF00406.17 CEP10563.1 - 3.3e-47 160.1 0.0 4.8e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CEP10563.1 - 3.6e-12 46.7 0.0 6.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP10563.1 - 8.8e-10 38.6 0.0 1.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP10563.1 - 4.5e-09 37.1 0.0 8.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEP10563.1 - 4.2e-06 26.0 0.0 6.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 CEP10563.1 - 9.3e-06 25.1 0.8 0.063 12.6 0.1 2.5 2 0 0 2 2 2 2 Thymidylate kinase SLAC1 PF03595.12 CEP10563.1 - 0.0024 16.5 0.0 0.0029 16.3 0.0 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel AAA_28 PF13521.1 CEP10563.1 - 0.095 12.6 0.4 0.26 11.2 0.0 2.0 3 0 0 3 3 3 0 AAA domain EF-1_beta_acid PF10587.4 CEP10563.1 - 2.2 8.4 5.3 5.6 7.2 3.7 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region zf-CCHC PF00098.18 CEP10564.1 - 0.0041 16.9 0.3 0.0041 16.9 0.2 4.3 5 0 0 5 5 5 2 Zinc knuckle zf-C4_Topoisom PF01396.14 CEP10564.1 - 0.052 13.0 5.2 1.2 8.7 0.2 3.2 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF164 PF02591.10 CEP10564.1 - 0.096 12.5 4.1 0.67 9.8 0.3 3.2 3 0 0 3 3 3 0 Putative zinc ribbon domain zf-HYPF PF07503.7 CEP10564.1 - 0.17 11.3 2.1 4.7 6.7 0.0 3.2 3 0 0 3 3 3 0 HypF finger zinc_ribbon_4 PF13717.1 CEP10564.1 - 0.17 11.6 4.4 4.5 7.0 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CEP10564.1 - 0.34 10.5 4.7 5.6 6.6 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 CEP10564.1 - 0.46 10.3 14.4 2 8.2 2.7 3.3 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CEP10564.1 - 1.4 8.5 8.7 0.68 9.4 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CEP10564.1 - 3 7.1 11.1 0.52 9.6 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.14 CEP10564.1 - 5.1 6.8 14.3 2.2 8.0 1.0 3.4 2 1 2 4 4 4 0 Hydrogenase expression/synthesis hypA family PHD PF00628.24 CEP10564.1 - 5.4 6.7 13.0 9.8 5.9 0.0 4.3 4 2 0 4 4 4 0 PHD-finger Ribosom_S12_S23 PF00164.20 CEP10565.1 - 8.2e-41 138.2 0.8 9.6e-41 138.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DnaJ PF00226.26 CEP10566.1 - 4.3e-28 96.8 1.8 6.8e-28 96.1 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CEP10566.1 - 6.6e-24 83.6 1.0 4.2e-20 71.4 0.1 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain RPT PF13446.1 CEP10566.1 - 0.018 14.4 0.1 0.099 12.0 0.0 2.2 2 1 1 3 3 3 0 A repeated domain in UCH-protein F-box-like PF12937.2 CEP10568.1 - 3e-08 33.2 0.5 3e-08 33.2 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP10568.1 - 6.2e-07 28.9 3.9 9.2e-07 28.3 0.2 2.9 3 0 0 3 3 3 1 F-box domain WD40 PF00400.27 CEP10569.1 - 2.1e-11 43.2 12.3 0.13 12.1 0.0 7.6 8 1 1 9 9 9 5 WD domain, G-beta repeat Lactonase PF10282.4 CEP10569.1 - 7e-06 25.3 0.0 0.00015 20.9 0.0 2.3 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Kelch_6 PF13964.1 CEP10569.1 - 0.031 14.4 1.5 4.5 7.6 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Neisseria_PilC PF05567.6 CEP10569.1 - 0.079 11.9 0.1 0.57 9.1 0.0 2.1 2 1 0 2 2 2 0 Neisseria PilC beta-propeller domain Pribosyl_synth PF14572.1 CEP10570.1 - 6.9e-40 136.7 1.2 5.3e-33 114.3 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CEP10570.1 - 1.8e-32 111.5 0.0 7.2e-32 109.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase SCP2 PF02036.12 CEP10570.1 - 2.3e-16 59.9 0.1 4.2e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Pribosyltran PF00156.22 CEP10570.1 - 7.4e-11 41.8 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CEP10570.1 - 0.0048 16.1 0.1 0.0091 15.2 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase YliH PF10799.3 CEP10570.1 - 0.044 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) COQ7 PF03232.8 CEP10571.1 - 8e-72 240.2 0.0 9.5e-72 240.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF4240 PF14024.1 CEP10571.1 - 0.084 12.7 0.0 17 5.3 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4240) Rubrerythrin PF02915.12 CEP10571.1 - 0.09 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Rubrerythrin DUF4499 PF14934.1 CEP10572.1 - 3.6e-10 39.6 0.3 5.7e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.4 CEP10572.1 - 2.2e-07 31.0 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Peptidase_M49 PF03571.10 CEP10573.1 - 1.7e-213 709.6 1.0 2.1e-213 709.3 0.7 1.1 1 0 0 1 1 1 1 Peptidase family M49 Peptidase_M24 PF00557.19 CEP10574.1 - 8.9e-49 165.8 0.0 1.8e-48 164.8 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CEP10574.1 - 1.4e-22 79.4 0.0 2.7e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain PLDc_2 PF13091.1 CEP10575.1 - 4.3e-26 91.1 0.9 8.4e-26 90.1 0.1 1.9 2 0 0 2 2 2 1 PLD-like domain DUF1669 PF07894.7 CEP10575.1 - 0.00094 18.4 0.0 0.00094 18.4 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1669) PLDc PF00614.17 CEP10575.1 - 0.02 14.6 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Phospholipase D Active site motif Pkinase PF00069.20 CEP10576.1 - 4.2e-13 49.0 0.0 2e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10576.1 - 0.0032 16.5 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-binding PF00249.26 CEP10577.1 - 8.2e-13 48.1 0.5 2.5e-12 46.6 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP10577.1 - 2.2e-11 43.6 2.7 2.3e-11 43.6 0.7 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain CHDCT2 PF08074.6 CEP10577.1 - 0.0051 16.5 4.7 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain Rap1_C PF11626.3 CEP10577.1 - 0.14 12.0 1.3 0.43 10.5 0.1 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Carn_acyltransf PF00755.15 CEP10578.1 - 2.7e-170 567.3 0.0 3.2e-170 567.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FAD_binding_2 PF00890.19 CEP10579.1 - 1.7e-123 412.5 5.3 2.1e-123 412.2 3.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CEP10579.1 - 7e-48 161.7 0.9 1.1e-47 161.0 0.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 CEP10579.1 - 2.3e-07 30.9 0.0 0.00081 19.3 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEP10579.1 - 3e-06 26.4 0.6 0.0045 16.1 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 CEP10579.1 - 2.2e-05 23.5 2.0 0.012 14.5 1.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 CEP10579.1 - 0.00013 20.9 0.2 0.00084 18.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CEP10579.1 - 0.0036 16.4 0.3 0.0059 15.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CEP10579.1 - 0.048 12.1 2.7 0.31 9.4 0.6 2.8 4 0 0 4 4 4 0 HI0933-like protein Pyr_redox_3 PF13738.1 CEP10579.1 - 0.09 12.8 1.2 0.83 9.6 0.2 2.7 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Uso1_p115_C PF04871.8 CEP10581.1 - 0.022 14.6 0.4 0.022 14.6 0.3 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region XhlA PF10779.4 CEP10581.1 - 0.091 12.6 1.6 0.32 10.9 1.1 1.9 1 0 0 1 1 1 0 Haemolysin XhlA Shugoshin_N PF07558.6 CEP10581.1 - 0.17 11.6 1.2 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region AMP-binding PF00501.23 CEP10582.1 - 1.2e-73 247.8 0.3 1.1e-37 129.4 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CEP10582.1 - 5.5e-18 65.6 0.0 1.3e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TRAP_alpha PF03896.11 CEP10583.1 - 0.0089 15.0 0.9 0.011 14.7 0.6 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 CEP10583.1 - 0.025 12.4 0.0 0.03 12.2 0.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 CEP10583.1 - 0.031 13.9 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 FAM176 family GRP PF07172.6 CEP10583.1 - 0.06 13.8 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 Glycine rich protein family DUF2981 PF11200.3 CEP10583.1 - 0.065 12.3 5.4 0.081 11.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Tetraspannin PF00335.15 CEP10583.1 - 0.097 11.9 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetraspanin family CDV3 PF15359.1 CEP10583.1 - 0.1 12.6 7.7 0.19 11.8 5.3 1.5 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 DUF2457 PF10446.4 CEP10583.1 - 0.4 9.3 15.6 0.47 9.1 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 CEP10583.1 - 1.7 6.4 9.1 1.9 6.3 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_18 PF00704.23 CEP10584.1 - 3e-60 204.5 7.7 1.7e-43 149.4 0.9 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 CEP10584.1 - 2.6e-11 42.9 11.0 8.7e-11 41.2 7.6 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain CBM_5_12_2 PF14600.1 CEP10584.1 - 8.8e-05 22.0 4.9 8.8e-05 22.0 3.4 2.2 2 0 0 2 2 2 1 Cellulose-binding domain Radical_SAM PF04055.16 CEP10585.1 - 1.4e-27 96.8 0.0 2.6e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 CEP10585.1 - 4.5e-23 81.1 0.0 1.8e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_1 PF00258.20 CEP10585.1 - 7.5e-23 81.1 0.0 1.5e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_NdrI PF07972.6 CEP10585.1 - 0.031 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 CEP10585.1 - 0.11 12.4 0.3 0.53 10.2 0.1 2.0 2 0 0 2 2 2 0 Flavodoxin domain TMEM164 PF14808.1 CEP10586.1 - 3.7e-13 49.2 0.0 4.6e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 TMEM164 family Lipoprotein_11 PF03260.8 CEP10586.1 - 0.013 14.5 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein FimP PF09766.4 CEP10587.1 - 0.0052 15.9 0.2 0.0072 15.4 0.2 1.2 1 0 0 1 1 1 1 Fms-interacting protein PINIT PF14324.1 CEP10588.1 - 3.1e-22 79.2 0.3 6.5e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 CEP10588.1 - 3.1e-20 71.4 0.8 5.9e-20 70.5 0.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CEP10588.1 - 3.4e-07 29.6 0.4 8.9e-07 28.3 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CytochromB561_N PF09786.4 CEP10588.1 - 0.14 10.5 5.4 0.24 9.8 3.8 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF1312 PF07009.6 CEP10588.1 - 0.27 11.0 4.0 0.34 10.7 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1312) Mucin PF01456.12 CEP10588.1 - 0.31 10.8 9.1 0.57 9.9 6.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein EF-hand_4 PF12763.2 CEP10589.1 - 7.6e-35 118.7 0.0 1.2e-30 105.3 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 CEP10589.1 - 2.1e-25 89.5 5.7 2.1e-25 89.5 3.9 1.6 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 CEP10589.1 - 9.8e-07 27.6 0.1 2.6e-05 23.2 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CEP10589.1 - 3.7e-05 23.7 0.0 0.0032 17.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CEP10589.1 - 7.3e-05 22.3 0.5 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CEP10589.1 - 0.00027 20.5 1.2 0.2 11.6 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CEP10589.1 - 0.06 12.7 0.1 0.21 11.0 0.1 1.9 1 0 0 1 1 1 0 EF hand SlyX PF04102.7 CEP10589.1 - 0.073 13.4 6.4 2.6 8.4 0.5 2.6 2 0 0 2 2 2 0 SlyX Laminin_II PF06009.7 CEP10589.1 - 0.083 12.6 9.8 0.13 12.0 0.9 2.2 1 1 1 2 2 2 0 Laminin Domain II HisKA PF00512.20 CEP10589.1 - 0.092 12.7 1.1 0.23 11.4 0.7 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF972 PF06156.8 CEP10589.1 - 0.38 11.1 7.1 0.51 10.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF1720 PF08226.6 CEP10589.1 - 0.67 10.0 48.6 1.2e+03 -0.5 33.7 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Fib_alpha PF08702.5 CEP10589.1 - 1.2 9.2 5.7 2.3 8.3 3.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ribosomal_L36e PF01158.13 CEP10590.1 - 1.5e-38 130.7 4.6 1.7e-38 130.5 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 CEP10590.1 - 0.0094 15.0 0.1 0.0097 15.0 0.1 1.1 1 0 0 1 1 1 1 LemA family priB_priC PF07445.7 CEP10590.1 - 0.019 14.4 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Primosomal replication protein priB and priC 4HB_MCP_1 PF12729.2 CEP10590.1 - 0.048 13.0 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction PK PF00224.16 CEP10591.1 - 2.5e-165 549.2 3.7 3.2e-165 548.9 2.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CEP10591.1 - 3.7e-31 107.1 0.1 1.3e-30 105.3 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CEP10591.1 - 5.1e-06 25.5 0.3 1.1e-05 24.3 0.2 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ECH_C PF13766.1 CEP10592.1 - 0.00015 21.9 0.1 0.00069 19.7 0.0 2.2 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region YL1_C PF08265.6 CEP10592.1 - 2.2 7.9 5.9 15 5.2 0.1 4.1 5 0 0 5 5 5 0 YL1 nuclear protein C-terminal domain Pkinase PF00069.20 CEP10593.1 - 7e-76 254.8 0.0 1e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10593.1 - 7.1e-38 130.1 0.0 1e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP10593.1 - 2.8e-09 36.3 0.0 1.9e-08 33.6 0.0 2.0 1 1 0 2 2 2 1 Kinase-like UBA_2 PF08587.6 CEP10593.1 - 4e-05 23.7 1.3 8.7e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) RIO1 PF01163.17 CEP10593.1 - 0.00052 19.4 0.1 0.0009 18.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family KA1 PF02149.14 CEP10593.1 - 0.0026 17.1 0.1 0.009 15.4 0.0 2.0 2 0 0 2 2 2 1 Kinase associated domain 1 YukC PF10140.4 CEP10593.1 - 0.0031 16.1 0.1 0.0048 15.5 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 CEP10593.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CEP10593.1 - 0.033 13.2 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spc24 PF08286.6 CEP10594.1 - 0.0023 17.5 1.8 0.0023 17.5 1.2 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 HIM1 PF08732.5 CEP10594.1 - 0.027 12.9 0.1 4.4 5.6 0.0 2.0 1 1 1 2 2 2 0 HIM1 DUF3417 PF11897.3 CEP10594.1 - 0.084 12.8 2.7 0.092 12.7 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) AAA_13 PF13166.1 CEP10594.1 - 0.21 10.0 10.2 0.23 9.8 7.1 1.1 1 0 0 1 1 1 0 AAA domain CPSase_L_D3 PF02787.14 CEP10594.1 - 0.46 10.2 3.9 0.76 9.5 0.9 2.3 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain YpjP PF14005.1 CEP10594.1 - 0.57 9.9 3.8 0.5 10.1 0.4 2.3 2 1 0 2 2 2 0 YpjP-like protein V_ATPase_I PF01496.14 CEP10594.1 - 5.2 4.7 7.9 5.6 4.6 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kinesin-relat_1 PF12711.2 CEP10594.1 - 7.7 6.9 18.1 2.6 8.4 8.2 2.6 2 1 0 2 2 2 0 Kinesin motor WD40 PF00400.27 CEP10595.1 - 8.3e-52 171.3 22.5 3.2e-09 36.3 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 CEP10595.1 - 1.5e-23 82.5 0.2 3.1e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CEP10595.1 - 7.3e-05 21.0 8.5 0.18 9.9 0.1 4.6 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Sel1 PF08238.7 CEP10596.1 - 1e-20 73.6 4.6 8.3e-09 35.8 0.4 4.3 4 0 0 4 4 4 3 Sel1 repeat TPR_3 PF07720.7 CEP10596.1 - 0.016 14.9 0.4 0.68 9.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP10596.1 - 0.037 13.6 4.7 4.5 6.9 0.5 3.3 3 1 1 4 4 4 0 TPR repeat MtlR PF05068.7 CEP10597.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Mannitol repressor Peptidase_M24 PF00557.19 CEP10598.1 - 1.2e-22 80.5 0.1 1.6e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 mit_SMPDase PF14724.1 CEP10599.1 - 0.00023 19.1 0.9 0.00054 17.8 0.6 1.6 2 0 0 2 2 2 1 Mitochondrial-associated sphingomyelin phosphodiesterase WD40 PF00400.27 CEP10600.1 - 3.4e-57 188.3 19.8 2.9e-09 36.4 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP10600.1 - 1.7e-09 36.4 6.9 0.13 10.4 0.1 5.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP10600.1 - 8e-08 31.8 1.1 1.5e-07 31.0 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP10600.1 - 7.1e-05 22.3 0.2 0.00014 21.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CEP10600.1 - 0.0001 21.8 0.0 0.0048 16.3 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.1 CEP10600.1 - 0.00016 21.3 0.0 5.5 6.8 0.0 4.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Bromodomain PF00439.20 CEP10601.1 - 2e-44 149.4 1.6 1.7e-21 75.8 0.1 2.7 2 0 0 2 2 2 2 Bromodomain MUG2_C PF08593.5 CEP10601.1 - 0.058 13.6 1.1 3.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Meiotically up-regulated glycoproteins C-terminal zf-met PF12874.2 CEP10602.1 - 1.4e-08 34.5 21.5 5.6e-05 23.1 1.4 3.8 3 0 0 3 3 3 3 Zinc-finger of C2H2 type DUF629 PF04780.7 CEP10602.1 - 0.00014 20.5 7.3 0.073 11.5 0.3 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 CEP10602.1 - 0.0016 18.4 15.8 0.28 11.3 0.1 4.4 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CEP10602.1 - 0.0019 18.3 2.0 0.0019 18.3 1.4 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP10602.1 - 0.0081 16.4 1.7 0.0081 16.4 1.2 4.1 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-Dof PF02701.10 CEP10602.1 - 0.035 14.0 0.5 7 6.6 0.0 2.7 2 0 0 2 2 2 0 Dof domain, zinc finger zf-C2H2_jaz PF12171.3 CEP10602.1 - 0.035 14.2 1.6 0.035 14.2 1.1 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zinc-ribbons_6 PF07191.7 CEP10602.1 - 0.37 10.6 10.5 7.1 6.4 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbons Paired_CXXCH_1 PF09699.5 CEP10602.1 - 0.7 9.4 5.6 5.4 6.6 1.0 2.7 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) RRN7 PF11781.3 CEP10602.1 - 2.3 7.7 5.5 20 4.7 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Homeobox PF00046.24 CEP10603.1 - 3.7e-16 58.4 3.0 7.2e-16 57.5 2.1 1.5 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 CEP10603.1 - 0.0048 16.5 0.4 0.031 13.9 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain Homeobox_KN PF05920.6 CEP10603.1 - 0.021 14.5 0.0 0.078 12.7 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain GerE PF00196.14 CEP10603.1 - 0.061 12.6 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family RNA_pol_3_Rpc31 PF11705.3 CEP10603.1 - 0.089 12.7 5.0 0.038 13.9 1.3 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.1 CEP10603.1 - 0.38 10.4 3.1 0.65 9.6 2.2 1.5 1 0 0 1 1 1 0 FAM176 family GIY-YIG PF01541.19 CEP10604.1 - 0.23 11.8 2.3 0.99 9.8 1.6 2.1 1 0 0 1 1 1 0 GIY-YIG catalytic domain Imm20 PF15568.1 CEP10604.1 - 0.53 10.1 4.5 3 7.7 0.0 3.3 2 1 0 3 3 3 0 Immunity protein 20 DUF4140 PF13600.1 CEP10604.1 - 0.95 9.9 13.5 0.4 11.1 0.2 4.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) USP8_interact PF08941.5 CEP10604.1 - 4.4 6.6 10.6 3.3 7.0 1.7 2.8 2 1 0 2 2 2 0 USP8 interacting PAC2 PF09754.4 CEP10605.1 - 6.1e-26 91.6 0.0 9.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 PAC2 family EB1 PF03271.12 CEP10606.1 - 5.5e-16 58.3 0.5 1.1e-15 57.4 0.3 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CEP10606.1 - 6.6e-06 26.1 0.5 9.7e-06 25.5 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 CEP10606.1 - 0.066 11.3 0.0 0.084 11.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1180 PF06679.7 CEP10606.1 - 6.8 6.5 5.7 1.6 8.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2361 PF10153.4 CEP10607.1 - 3.3e-27 94.9 12.3 3.3e-27 94.9 8.5 2.1 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Glyco_transf_92 PF01697.22 CEP10607.1 - 0.0073 15.6 1.8 0.0088 15.3 1.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 RWD PF05773.17 CEP10607.1 - 0.028 14.3 2.7 0.05 13.5 1.7 1.5 1 1 0 1 1 1 0 RWD domain DUF904 PF06005.7 CEP10607.1 - 0.052 13.8 3.5 0.052 13.8 2.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 CEP10607.1 - 0.14 11.9 20.9 0.14 11.9 10.1 3.2 1 1 1 2 2 2 0 Tropomyosin like V_ATPase_I PF01496.14 CEP10607.1 - 8.4 4.1 10.3 11 3.7 6.9 1.2 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family SPRY PF00622.23 CEP10608.1 - 2.7e-19 69.4 0.2 4.4e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 SPRY domain Candida_ALS_N PF11766.3 CEP10608.1 - 0.089 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding E1-E2_ATPase PF00122.15 CEP10609.1 - 1.4e-57 194.4 2.4 1.4e-57 194.4 1.7 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CEP10609.1 - 4.6e-22 79.4 0.2 5.8e-21 75.8 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CEP10609.1 - 9.3e-22 77.4 2.7 9.3e-22 77.4 1.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 CEP10609.1 - 1.3e-17 63.5 0.0 2.9e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CEP10609.1 - 2e-17 62.4 0.0 6.6e-17 60.7 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEP10609.1 - 6.1e-15 55.8 0.0 1.4e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Borrelia_P13 PF05628.7 CEP10609.1 - 0.0056 16.4 0.0 0.021 14.6 0.0 2.0 1 0 0 1 1 1 1 Borrelia membrane protein P13 Hydrolase_3 PF08282.7 CEP10609.1 - 0.0085 15.6 0.3 0.0085 15.6 0.2 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 CEP10609.1 - 4.2 5.8 8.4 3.7 6.0 0.6 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) PH PF00169.24 CEP10610.1 - 0.00082 19.5 2.7 0.00086 19.4 0.4 2.2 2 1 0 2 2 2 1 PH domain RNase_P_Rpp14 PF01900.14 CEP10611.1 - 2.4e-08 33.8 0.1 2.9e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family PAS_3 PF08447.6 CEP10612.1 - 1.3e-13 50.8 0.1 4.1e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 CEP10612.1 - 6.2e-08 32.9 0.1 0.0025 18.1 0.0 2.9 2 1 1 3 3 3 2 PAS domain PAS PF00989.19 CEP10612.1 - 1.1e-07 31.6 0.0 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 CEP10612.1 - 1.1e-07 31.7 0.2 6.8e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 CEP10612.1 - 0.055 13.5 0.0 2.3 8.3 0.0 2.4 2 1 0 2 2 2 0 PAS fold STT3 PF02516.9 CEP10613.1 - 1.6e-139 465.9 43.9 1.1e-135 453.3 27.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 CEP10613.1 - 0.00013 21.8 16.7 0.00013 21.8 11.6 3.5 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ZapA PF05164.8 CEP10614.1 - 0.12 12.3 2.7 12 5.9 0.1 3.6 3 0 0 3 3 3 0 Cell division protein ZapA Tape_meas_lam_C PF09718.5 CEP10614.1 - 0.13 12.2 0.4 0.39 10.6 0.3 1.8 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YolD PF08863.5 CEP10614.1 - 0.16 11.8 3.1 2.7 7.8 0.1 3.1 2 1 1 3 3 3 0 YolD-like protein Baculo_PEP_C PF04513.7 CEP10614.1 - 0.67 9.7 7.0 2.2 8.0 0.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.6 CEP10614.1 - 1.6 8.4 6.3 0.72 9.6 0.3 2.7 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Trehalase PF01204.13 CEP10615.1 - 7.8e-127 424.0 17.2 1.4e-117 393.4 5.1 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 CEP10615.1 - 1.1e-07 30.8 7.2 9.9e-07 27.7 5.0 2.0 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Hydrolase_6 PF13344.1 CEP10617.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF59 PF01883.14 CEP10620.1 - 0.096 12.6 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF59 IFRD PF05004.8 CEP10621.1 - 0.0076 15.3 0.0 0.0099 14.9 0.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Peptidase_M64 PF09471.5 CEP10621.1 - 0.12 12.0 0.4 0.15 11.6 0.3 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 rve PF00665.21 CEP10622.1 - 1.1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP10622.1 - 0.00028 20.2 1.5 0.0011 18.2 0.7 2.1 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger DDE_3 PF13358.1 CEP10623.1 - 1.6e-28 99.3 0.1 9.8e-28 96.7 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP10623.1 - 1.9e-06 27.3 0.0 5.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP10623.1 - 0.00036 20.4 0.2 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP10623.1 - 0.0012 19.0 0.0 0.0078 16.4 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_1 PF03184.14 CEP10623.1 - 0.0029 16.7 0.1 0.019 14.1 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP10623.1 - 0.0031 17.6 0.0 0.0075 16.3 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_IclR PF09339.5 CEP10623.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_1 PF01527.15 CEP10623.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Transposase Phage_AlpA PF05930.7 CEP10623.1 - 0.068 12.9 0.0 0.88 9.3 0.0 2.5 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Retrotrans_gag PF03732.12 CEP10626.1 - 7.8e-16 57.9 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Mpv17_PMP22 PF04117.7 CEP10627.1 - 3.1e-22 77.9 3.1 8.2e-22 76.6 0.9 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF2414 PF10309.4 CEP10628.1 - 0.04 13.6 0.1 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) Transposase_31 PF04754.7 CEP10628.1 - 0.04 13.2 0.0 0.093 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative transposase, YhgA-like DUF2887 PF11103.3 CEP10628.1 - 0.066 12.8 0.0 0.2 11.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2887) MRC1 PF09444.5 CEP10629.1 - 1.6e-17 64.2 11.7 1.6e-17 64.2 8.1 7.4 4 2 2 6 6 6 1 MRC1-like domain RasGEF PF00617.14 CEP10630.1 - 7.8e-46 156.1 3.8 3.9e-45 153.8 2.7 2.2 1 1 0 1 1 1 1 RasGEF domain NOA36 PF06524.7 CEP10630.1 - 7.5 5.7 23.8 0.065 12.4 7.5 2.7 3 0 0 3 3 3 0 NOA36 protein Nop14 PF04147.7 CEP10631.1 - 0.007 14.3 29.8 0.008 14.1 20.6 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CEP10631.1 - 0.029 12.4 22.2 0.033 12.2 15.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CEP10631.1 - 0.036 13.4 15.4 0.039 13.3 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 CEP10631.1 - 0.4 8.8 8.1 0.42 8.8 5.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CBP4 PF07960.6 CEP10631.1 - 1.1 8.9 5.2 1.5 8.4 3.6 1.2 1 0 0 1 1 1 0 CBP4 DUF2457 PF10446.4 CEP10631.1 - 1.5 7.4 39.1 1.9 7.1 27.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 CEP10631.1 - 1.6 7.9 25.4 2.2 7.4 17.6 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.6 CEP10631.1 - 2.2 7.7 27.7 3.2 7.2 19.2 1.3 1 0 0 1 1 1 0 PPP4R2 Vfa1 PF08432.5 CEP10631.1 - 2.5 8.0 18.5 3.6 7.5 12.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 CEP10631.1 - 3.3 7.2 15.1 5 6.6 10.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.8 CEP10631.1 - 3.7 6.1 20.2 4.4 5.9 14.0 1.1 1 0 0 1 1 1 0 Paf1 BUD22 PF09073.5 CEP10631.1 - 5 6.0 24.9 6.1 5.8 17.3 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.7 CEP10631.1 - 7 5.6 27.3 9.6 5.2 19.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_A_exo1 PF01612.15 CEP10632.1 - 0.0017 17.8 0.0 0.0078 15.7 0.0 2.0 1 1 1 2 2 2 1 3'-5' exonuclease zf-RING_4 PF14570.1 CEP10633.1 - 0.012 15.1 0.2 0.024 14.2 0.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Helitron_like_N PF14214.1 CEP10635.1 - 4.8e-68 228.5 0.0 7.7e-68 227.8 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 CEP10635.1 - 0.0023 16.7 0.0 0.6 8.7 0.0 2.2 2 0 0 2 2 2 2 Bacteriophage replication gene A protein (GPA) DUF3296 PF11726.3 CEP10635.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) PIF1 PF05970.9 CEP10636.1 - 6.2e-12 45.1 0.0 7.6e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase SLS PF14611.1 CEP10638.1 - 1.5e-15 57.1 3.4 2.9e-15 56.2 2.4 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.24 CEP10638.1 - 1.2e-07 31.2 0.1 3.6e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CEP10638.1 - 0.0018 17.8 0.1 0.0047 16.5 0.1 1.7 1 0 0 1 1 1 1 KH domain YmgB PF10798.3 CEP10638.1 - 0.31 10.8 4.3 0.25 11.1 0.1 2.8 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR EF-hand_1 PF00036.27 CEP10639.1 - 4.1e-19 66.3 10.3 6.6e-10 37.5 0.4 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CEP10639.1 - 1.9e-16 59.9 4.2 5.2e-16 58.5 2.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CEP10639.1 - 9.1e-13 46.9 6.5 2.8e-08 32.9 0.2 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CEP10639.1 - 9.2e-13 46.9 7.6 1.4e-07 30.5 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CEP10639.1 - 2.4e-10 39.8 11.2 2e-08 33.7 1.5 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 CEP10639.1 - 1.3e-05 24.8 4.9 0.00011 21.9 1.4 2.8 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CEP10639.1 - 0.00019 21.4 0.3 0.00029 20.8 0.2 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CEP10639.1 - 0.00027 20.8 0.9 0.00061 19.6 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain TerB PF05099.8 CEP10639.1 - 0.0076 15.9 0.1 0.036 13.8 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TerB DUF2267 PF10025.4 CEP10639.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Dockerin_1 PF00404.13 CEP10639.1 - 2.6 7.8 4.8 18 5.2 0.2 2.3 2 0 0 2 2 2 0 Dockerin type I repeat EF-hand_1 PF00036.27 CEP10640.1 - 7.2e-31 103.1 4.0 6.6e-08 31.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEP10640.1 - 6.3e-29 99.9 4.4 1.7e-14 53.7 1.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP10640.1 - 9.8e-21 71.7 6.2 3.8e-06 26.3 0.2 5.3 3 2 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CEP10640.1 - 1.5e-18 66.0 6.5 9.9e-06 25.0 0.0 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CEP10640.1 - 4.7e-17 60.4 10.0 1.2e-05 24.3 0.0 5.7 4 3 2 6 6 6 3 EF hand EF-hand_4 PF12763.2 CEP10640.1 - 2.3e-10 40.1 3.1 3.2e-05 23.6 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CEP10640.1 - 1e-06 28.7 4.2 0.00039 20.4 1.5 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CEP10640.1 - 1.3e-05 24.9 0.2 0.00094 19.0 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain TerB PF05099.8 CEP10640.1 - 0.008 15.9 1.5 0.43 10.3 0.1 2.9 1 1 2 3 3 3 1 Tellurite resistance protein TerB Adenine_glyco PF03352.8 CEP10640.1 - 0.021 14.3 1.4 0.031 13.8 0.8 1.4 1 1 0 1 1 1 0 Methyladenine glycosylase VCBS PF13517.1 CEP10640.1 - 0.063 13.6 0.5 14 6.0 0.5 3.0 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella p25-alpha PF05517.7 CEP10640.1 - 0.075 13.2 0.8 0.32 11.2 0.1 2.0 1 1 0 2 2 2 0 p25-alpha Rep_fac-A_C PF08646.5 CEP10640.1 - 0.13 11.9 1.0 0.42 10.3 0.2 1.9 1 1 1 2 2 2 0 Replication factor-A C terminal domain Claudin_2 PF13903.1 CEP10641.1 - 0.0058 16.3 2.2 0.0058 16.3 1.5 2.9 3 1 1 4 4 4 2 PMP-22/EMP/MP20/Claudin tight junction Cytochrom_B_N PF00033.14 CEP10641.1 - 0.049 12.9 0.3 0.049 12.9 0.2 2.6 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF3246 PF11596.3 CEP10641.1 - 0.68 9.1 5.3 0.082 12.1 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) FBP PF07299.6 CEP10644.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) Ribosomal_L31e PF01198.14 CEP10645.1 - 4.4e-33 112.7 3.0 5.5e-33 112.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Baculo_PEP_C PF04513.7 CEP10646.1 - 0.021 14.6 1.0 0.057 13.2 0.7 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_integrase PF00589.17 CEP10646.1 - 0.034 13.8 0.1 0.15 11.7 0.0 2.1 1 1 0 1 1 1 0 Phage integrase family LETM1 PF07766.8 CEP10647.1 - 5.6e-105 350.1 1.4 5.6e-105 350.1 1.0 2.4 2 1 2 4 4 4 1 LETM1-like protein SAP PF02037.22 CEP10647.1 - 0.0011 18.3 0.3 0.068 12.6 0.0 3.5 4 0 0 4 4 4 1 SAP domain ThiF PF00899.16 CEP10648.1 - 3.1e-37 127.4 1.0 2.1e-36 124.7 0.2 2.5 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 CEP10648.1 - 5e-29 99.6 0.2 1.4e-28 98.2 0.1 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CEP10648.1 - 3.5e-21 74.3 3.3 7.9e-21 73.1 2.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CEP10648.1 - 5.6e-08 32.7 1.0 5.6e-08 32.7 0.7 2.6 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 CEP10648.1 - 1.4e-05 25.2 0.2 9.5e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CEP10648.1 - 6.3e-05 23.0 0.1 0.00018 21.5 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CEP10648.1 - 0.054 12.4 0.1 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase AhpC-TSA PF00578.16 CEP10649.1 - 0.0013 18.4 0.1 0.051 13.2 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family ARPC4 PF05856.7 CEP10651.1 - 9.3e-78 259.4 4.0 1e-77 259.3 2.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) LAG1-DNAbind PF09271.6 CEP10652.1 - 2.4e-34 118.7 4.4 6.1e-34 117.4 0.1 3.0 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 CEP10652.1 - 3.3e-26 91.9 1.6 1.6e-23 83.2 0.7 3.9 2 1 0 2 2 2 1 Beta-trefoil DNA-binding domain TIG PF01833.19 CEP10652.1 - 0.00084 19.2 0.0 0.0057 16.6 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain BAF1_ABF1 PF04684.8 CEP10652.1 - 0.046 12.5 13.1 0.077 11.8 9.1 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CEP10652.1 - 0.16 11.3 9.6 1.5 8.1 6.6 2.5 1 1 0 1 1 1 0 Spt20 family Suf PF05843.9 CEP10652.1 - 2.2 7.9 9.5 0.42 10.3 0.8 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) tRNA_anti-codon PF01336.20 CEP10653.1 - 2.9e-11 43.0 0.1 1e-10 41.2 0.1 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CH PF00307.26 CEP10654.1 - 4.1e-24 84.6 7.4 2.2e-13 50.1 0.1 4.7 5 0 0 5 5 5 2 Calponin homology (CH) domain GAS2 PF02187.12 CEP10654.1 - 7.5e-07 28.8 0.1 2.9e-06 26.9 0.1 2.0 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.3 CEP10654.1 - 7.6e-06 25.4 0.1 8.4e-05 22.1 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain PhoD PF09423.5 CEP10655.1 - 7.6e-08 31.3 0.4 0.00021 19.9 0.6 2.7 2 1 0 2 2 2 2 PhoD-like phosphatase Myb_DNA-binding PF00249.26 CEP10656.1 - 0.0044 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sybindin PF04099.7 CEP10657.1 - 5.2e-23 81.3 0.4 1.1e-22 80.3 0.3 1.5 1 1 0 1 1 1 1 Sybindin-like family KIAA1430 PF13879.1 CEP10659.1 - 0.007 16.7 0.4 0.011 16.1 0.3 1.2 1 0 0 1 1 1 1 KIAA1430 homologue IncA PF04156.9 CEP10659.1 - 1.1 8.8 5.3 2.4 7.7 3.7 1.5 1 0 0 1 1 1 0 IncA protein Sel1 PF08238.7 CEP10660.1 - 3.9e-30 103.5 26.4 2e-08 34.5 0.2 8.5 8 0 0 8 8 8 6 Sel1 repeat Ras PF00071.17 CEP10663.1 - 6.3e-58 194.7 0.2 7.4e-58 194.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP10663.1 - 5e-20 72.1 0.0 9.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP10663.1 - 7.6e-15 54.5 0.0 8.8e-15 54.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP10663.1 - 5.1e-09 35.6 0.1 6.6e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP10663.1 - 2.6e-07 30.2 0.1 4e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP10663.1 - 3.5e-07 30.1 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 CEP10663.1 - 0.00056 19.3 0.0 0.0048 16.3 0.0 2.0 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CEP10663.1 - 0.00085 18.5 0.1 0.0014 17.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CEP10663.1 - 0.00097 18.8 0.1 0.0017 18.0 0.0 1.5 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.1 CEP10663.1 - 0.0012 19.0 0.0 0.0021 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CEP10663.1 - 0.0035 17.0 0.5 0.0059 16.3 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 CEP10663.1 - 0.0051 16.4 0.1 0.0095 15.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CEP10663.1 - 0.0051 16.3 0.3 0.028 13.9 0.1 2.1 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CEP10663.1 - 0.0056 16.3 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 CEP10663.1 - 0.006 15.6 0.7 0.03 13.3 0.1 2.1 2 1 0 2 2 2 1 Septin AAA_10 PF12846.2 CEP10663.1 - 0.0071 15.8 0.1 0.011 15.2 0.1 1.7 1 1 0 1 1 1 1 AAA-like domain ATP_bind_1 PF03029.12 CEP10663.1 - 0.0087 15.6 0.3 0.41 10.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 CEP10663.1 - 0.013 15.5 0.0 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 CEP10663.1 - 0.026 13.7 0.0 0.041 13.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 CEP10663.1 - 0.044 13.5 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CEP10663.1 - 0.057 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 CEP10663.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sod_Fe_C PF02777.13 CEP10664.1 - 2e-43 146.5 0.3 3.6e-43 145.7 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CEP10664.1 - 5.8e-31 106.5 3.1 1.3e-30 105.4 2.2 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Alk_phosphatase PF00245.15 CEP10665.1 - 1.2e-102 343.7 0.1 1.4e-102 343.5 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 CEP10665.1 - 0.016 14.6 0.3 0.089 12.1 0.2 1.9 2 0 0 2 2 2 0 Metalloenzyme superfamily Phage_integrase PF00589.17 CEP10666.1 - 2.8e-06 27.0 0.0 6.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family RVT_3 PF13456.1 CEP10666.1 - 0.00022 20.9 0.1 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like DUF2790 PF10976.3 CEP10667.1 - 0.11 12.2 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) RasGAP PF00616.14 CEP10668.1 - 7e-43 146.5 0.5 2.7e-42 144.6 0.1 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 CEP10668.1 - 4.9e-20 71.9 0.1 2.2e-19 69.8 0.1 2.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CEP10668.1 - 6.2e-08 32.2 0.4 1.7e-07 30.8 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT_2 PF13646.1 CEP10668.1 - 0.0052 17.0 0.2 30 4.9 0.0 4.7 4 1 0 4 4 4 0 HEAT repeats HEAT PF02985.17 CEP10668.1 - 0.021 14.8 0.3 0.021 14.8 0.2 3.8 3 0 0 3 3 3 0 HEAT repeat Peptidase_M13_N PF05649.8 CEP10669.1 - 1.6e-84 284.2 0.0 1.9e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CEP10669.1 - 9.7e-62 207.8 0.1 2.7e-61 206.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_MA_2 PF13485.1 CEP10669.1 - 0.028 14.4 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Peptidase_M48 PF01435.13 CEP10669.1 - 0.035 13.6 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M48 RNA_pol_A_CTD PF03118.10 CEP10669.1 - 0.082 12.3 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RVT_1 PF00078.22 CEP10670.1 - 3.2e-22 78.9 0.0 6.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP10670.1 - 3.8e-15 55.5 0.1 1.3e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP10670.1 - 5.2e-06 26.5 0.3 1.2e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tropomyosin_1 PF12718.2 CEP10670.1 - 0.2 11.4 7.3 0.58 9.9 4.1 2.0 2 0 0 2 2 2 0 Tropomyosin like GAS PF13851.1 CEP10670.1 - 0.27 10.3 7.0 0.46 9.6 4.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_integrase PF00589.17 CEP10671.1 - 5.4e-06 26.1 0.2 2.2e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Phage integrase family DUF1836 PF08876.6 CEP10671.1 - 0.088 12.5 0.2 0.14 11.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1836) RVT_1 PF00078.22 CEP10672.1 - 0.00075 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IFT43 PF15305.1 CEP10676.1 - 0.071 13.1 1.8 0.083 12.9 1.2 1.1 1 0 0 1 1 1 0 Intraflagellar transport protein 43 DUF202 PF02656.10 CEP10680.1 - 6e-21 74.4 0.6 6e-21 74.4 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1761 PF08570.5 CEP10680.1 - 0.11 12.5 3.3 0.48 10.4 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) YtpI PF14007.1 CEP10680.1 - 0.18 11.7 5.8 0.25 11.2 2.0 2.3 2 0 0 2 2 2 0 YtpI-like protein Cg6151-P PF10233.4 CEP10682.1 - 1.7e-05 24.7 0.3 1.9e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P HLH PF00010.21 CEP10683.1 - 3.8e-12 45.7 1.8 9.2e-12 44.4 1.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 CEP10683.1 - 0.022 14.4 1.6 0.022 14.4 1.1 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper LTXXQ PF07813.7 CEP10683.1 - 0.19 12.2 4.4 0.091 13.2 1.1 1.9 2 0 0 2 2 2 0 LTXXQ motif family protein DivIC PF04977.10 CEP10683.1 - 0.63 9.5 6.6 0.088 12.2 1.3 2.2 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 CEP10683.1 - 0.7 10.3 3.7 1.3 9.4 0.5 2.7 2 0 0 2 2 2 0 SlyX DUF1875 PF08961.5 CEP10683.1 - 3.1 7.0 9.4 0.11 11.8 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1875) ALMT PF11744.3 CEP10684.1 - 1.1e-21 76.9 6.4 3.9e-16 58.7 1.4 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 CEP10684.1 - 1.5e-16 60.4 11.1 1.5e-16 60.4 7.7 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2422 PF10337.4 CEP10684.1 - 5.5e-11 41.9 0.2 5.5e-11 41.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CEP10684.1 - 3e-10 40.1 5.8 6.5e-10 39.0 1.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 CEP10684.1 - 3.1e-10 39.1 15.8 1.4e-08 33.6 8.0 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein family Erf4 PF10256.4 CEP10684.1 - 0.0082 16.0 0.1 1.1 9.0 0.0 3.3 3 0 0 3 3 3 1 Golgin subfamily A member 7/ERF4 family RasGEF PF00617.14 CEP10685.1 - 5.6e-29 101.2 0.0 1.5e-17 63.9 0.0 2.6 1 1 1 2 2 2 2 RasGEF domain RasGEF_N PF00618.15 CEP10685.1 - 1.5e-17 63.5 3.7 4.1e-17 62.1 2.5 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Pex24p PF06398.6 CEP10686.1 - 1.3e-12 47.2 2.5 1.3e-12 47.2 1.7 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.1 CEP10686.1 - 0.013 15.4 0.3 0.053 13.5 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4476) Tom37_C PF11801.3 CEP10687.1 - 1.3e-17 64.1 2.7 9.8e-17 61.3 1.8 2.1 1 1 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 CEP10687.1 - 2.1e-16 59.9 0.0 4.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 CEP10687.1 - 6e-09 35.6 0.0 2.7e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP10687.1 - 5.4e-08 33.2 0.1 1.9e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP10687.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain IP_trans PF02121.13 CEP10688.1 - 1.9e-82 276.2 4.5 2.6e-82 275.7 3.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF1712 PF08217.6 CEP10689.1 - 7e-33 113.7 10.7 1.2e-27 96.5 0.2 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) DUF4396 PF14342.1 CEP10690.1 - 1.4e-27 96.5 2.1 1.6e-27 96.3 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DUF165 PF02592.10 CEP10690.1 - 0.085 13.0 0.3 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 ParA PF10609.4 CEP10692.1 - 7.5e-38 128.2 0.1 1.3e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CEP10692.1 - 1e-17 64.2 0.0 1.5e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CEP10692.1 - 6.3e-07 28.7 0.0 1.7e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CEP10692.1 - 2.7e-06 27.3 0.0 1.4e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 CEP10692.1 - 1.7e-05 24.0 0.7 5e-05 22.5 0.3 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 CEP10692.1 - 6.3e-05 21.8 0.6 9.3e-05 21.3 0.4 1.2 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 CEP10692.1 - 0.00099 18.5 0.1 0.0019 17.5 0.1 1.5 1 1 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 CEP10692.1 - 0.0049 16.3 0.2 0.014 14.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 CEP10692.1 - 0.0072 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_26 PF13500.1 CEP10692.1 - 0.014 15.0 0.2 0.92 9.0 0.4 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 CEP10692.1 - 0.019 14.1 0.1 0.037 13.2 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CEP10692.1 - 0.046 13.1 0.1 0.18 11.2 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.9 CEP10692.1 - 0.058 13.0 0.1 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CEP10692.1 - 0.089 12.2 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 CEP10692.1 - 0.12 11.6 1.4 0.23 10.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 CEP10692.1 - 0.29 10.9 1.5 4.1 7.2 0.2 2.6 2 1 0 2 2 2 0 Part of AAA domain Dus PF01207.12 CEP10693.1 - 2e-67 227.2 0.0 3.4e-66 223.2 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 CEP10693.1 - 1.4e-05 24.3 0.0 2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.12 CEP10693.1 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 CEP10693.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.16 CEP10693.1 - 0.032 13.2 0.0 0.21 10.5 0.0 1.9 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.10 CEP10693.1 - 0.085 11.9 0.0 0.2 10.7 0.0 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase DnaJ PF00226.26 CEP10694.1 - 0.014 15.1 1.0 2.4 7.9 0.1 2.7 2 0 0 2 2 2 0 DnaJ domain OrfB_Zn_ribbon PF07282.6 CEP10696.1 - 2.6e-09 36.5 1.9 4.9e-09 35.7 1.3 1.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Cytochrome_C7 PF14522.1 CEP10696.1 - 0.0012 18.4 0.5 0.0019 17.7 0.4 1.4 1 0 0 1 1 1 1 Cytochrome c7 Cytochrome_C554 PF13435.1 CEP10696.1 - 0.01 15.8 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 CEP10696.1 - 0.03 14.6 0.6 0.052 13.8 0.4 1.4 1 0 0 1 1 1 0 Cytochrome c3 zf-CHY PF05495.7 CEP10696.1 - 0.062 13.4 1.5 0.12 12.5 1.0 1.4 1 0 0 1 1 1 0 CHY zinc finger ArsA_ATPase PF02374.10 CEP10697.1 - 0.0039 16.2 0.2 1.2 8.0 0.1 2.5 2 0 0 2 2 2 2 Anion-transporting ATPase Retrotrans_gag PF03732.12 CEP10697.1 - 0.014 15.4 0.0 0.06 13.4 0.0 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein DNase_NucA_NucB PF14040.1 CEP10697.1 - 0.032 14.3 0.9 0.2 11.8 0.3 2.2 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB Abi_2 PF07751.6 CEP10697.1 - 0.14 12.2 0.1 0.14 12.2 0.0 2.2 3 0 0 3 3 3 0 Abi-like protein THOC7 PF05615.8 CEP10699.1 - 0.049 13.8 5.0 0.061 13.6 3.5 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 Cmyb_C PF09316.5 CEP10699.1 - 0.22 11.1 4.0 2.5 7.7 0.3 2.0 1 1 1 2 2 2 0 C-myb, C-terminal MerR_1 PF13411.1 CEP10700.1 - 0.019 14.7 0.3 0.065 13.0 0.2 1.9 1 1 0 1 1 1 0 MerR HTH family regulatory protein NUMOD1 PF07453.8 CEP10700.1 - 0.1 12.5 0.2 11 6.0 0.0 3.1 3 0 0 3 3 3 0 NUMOD1 domain Spore_III_AF PF09581.5 CEP10700.1 - 0.19 11.5 1.7 0.24 11.2 1.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) RVT_1 PF00078.22 CEP10701.1 - 2e-19 69.8 0.0 3.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 CEP10703.1 - 7.3e-13 48.4 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4508 PF14969.1 CEP10704.1 - 0.063 13.2 1.2 0.096 12.7 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) NTR PF01759.16 CEP10704.1 - 0.076 12.5 1.5 5 6.7 0.0 2.5 2 1 0 2 2 2 0 UNC-6/NTR/C345C module PIF1 PF05970.9 CEP10706.1 - 2.8e-35 121.9 0.0 2.4e-33 115.5 0.0 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP10706.1 - 1.2e-11 44.6 0.0 2.8e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP10706.1 - 1.3e-08 35.0 0.0 2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP10706.1 - 1.6e-05 24.5 0.1 5.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 CEP10706.1 - 3.8e-05 23.3 0.3 0.19 11.2 0.0 2.9 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CEP10706.1 - 0.00021 20.9 0.2 0.0031 17.0 0.1 2.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 CEP10706.1 - 0.00064 19.2 1.5 0.002 17.6 0.3 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP10706.1 - 0.00087 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CEP10706.1 - 0.0021 18.3 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CEP10706.1 - 0.0029 17.3 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 CEP10706.1 - 0.0043 16.9 0.2 0.032 14.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CEP10706.1 - 0.0055 15.7 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Septin PF00735.13 CEP10706.1 - 0.0057 15.7 0.1 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Septin DUF815 PF05673.8 CEP10706.1 - 0.0061 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 CEP10706.1 - 0.0081 15.8 0.1 0.1 12.2 0.1 2.1 2 0 0 2 2 2 1 NTPase AAA_23 PF13476.1 CEP10706.1 - 0.0085 16.4 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CEP10706.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEP10706.1 - 0.019 15.8 0.4 0.038 14.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CEP10706.1 - 0.019 14.8 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Herpes_Helicase PF02689.9 CEP10706.1 - 0.021 12.5 0.0 0.043 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase T2SE PF00437.15 CEP10706.1 - 0.021 13.7 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 CEP10706.1 - 0.023 14.1 0.1 0.12 11.8 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 CEP10706.1 - 0.024 14.9 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CEP10706.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IIGP PF05049.8 CEP10706.1 - 0.031 13.0 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RNA_helicase PF00910.17 CEP10706.1 - 0.038 14.1 0.0 0.086 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ArgK PF03308.11 CEP10706.1 - 0.044 12.5 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 CEP10706.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CEP10706.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 CEP10706.1 - 0.089 12.4 0.1 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 NACHT domain APS_kinase PF01583.15 CEP10706.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Miro PF08477.8 CEP10706.1 - 0.12 12.8 0.1 0.23 11.9 0.1 1.7 1 1 0 1 1 1 0 Miro-like protein zf-CCHC PF00098.18 CEP10707.1 - 0.00053 19.7 2.6 0.00093 19.0 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle LAGLIDADG_2 PF03161.8 CEP10708.1 - 0.024 14.5 2.9 1.2 9.0 0.5 2.1 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family DUF2410 PF10307.4 CEP10709.1 - 7.5e-41 139.6 0.0 2.3e-40 138.0 0.0 1.8 1 1 0 1 1 1 1 Hypothetical protein (DUF2410) Ion_trans PF00520.26 CEP10710.1 - 1.4e-23 83.2 16.0 1.9e-22 79.4 11.4 2.0 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 CEP10710.1 - 6.7e-10 38.5 11.4 6.7e-10 38.5 7.9 2.9 2 1 1 3 3 3 1 Ion channel DUF4383 PF14325.1 CEP10710.1 - 0.041 13.8 1.5 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) TPR_11 PF13414.1 CEP10711.1 - 9.2e-30 102.0 8.5 3.4e-11 42.6 0.0 5.4 3 2 2 5 5 5 5 TPR repeat DnaJ PF00226.26 CEP10711.1 - 5.3e-22 77.3 4.0 5.3e-22 77.3 2.7 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 CEP10711.1 - 5.2e-20 69.6 5.8 0.04 13.8 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 CEP10711.1 - 2.1e-18 65.0 5.3 0.00028 20.3 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CEP10711.1 - 1.1e-16 61.0 1.9 0.00012 22.6 0.4 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEP10711.1 - 3.5e-11 43.2 14.9 0.0017 18.6 0.1 6.6 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 CEP10711.1 - 5.1e-11 41.5 1.9 0.17 11.7 0.0 7.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP10711.1 - 6.4e-10 38.7 9.1 0.09 13.4 0.0 7.4 3 3 5 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP10711.1 - 7.3e-08 32.0 3.5 0.014 15.5 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEP10711.1 - 2.2e-07 30.6 6.6 0.056 13.3 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CEP10711.1 - 5e-06 26.6 10.9 2.3 8.8 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 CEP10711.1 - 5.1e-06 26.5 12.7 0.091 12.9 0.2 5.0 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CEP10711.1 - 0.0011 18.8 12.2 0.1 12.5 0.1 4.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEP10711.1 - 0.002 17.8 8.8 21 5.2 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEP10711.1 - 0.0036 17.1 1.4 0.53 10.2 0.0 3.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 CEP10711.1 - 0.0038 17.3 15.1 0.75 9.9 0.0 5.5 2 2 3 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.12 CEP10711.1 - 0.025 14.8 1.5 11 6.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain OHCU_decarbox PF09349.5 CEP10711.1 - 0.18 12.1 6.5 0.62 10.3 0.1 2.5 2 0 0 2 2 2 0 OHCU decarboxylase Pkinase PF00069.20 CEP10712.1 - 2.1e-54 184.4 0.1 6.7e-54 182.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10712.1 - 1.2e-22 80.2 0.0 2.5e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP10712.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CEP10712.1 - 0.013 14.8 0.1 0.013 14.8 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 CEP10712.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_zinc_N PF00107.21 CEP10713.1 - 8.2e-37 125.6 0.1 1.3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP10713.1 - 1.3e-11 45.4 0.0 4.2e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP10713.1 - 1.2e-09 37.8 0.0 3.3e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 CEP10713.1 - 0.0092 16.0 0.5 0.016 15.1 0.4 1.4 1 1 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 CEP10713.1 - 0.022 14.3 3.0 0.05 13.1 1.1 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 CEP10713.1 - 0.029 14.3 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain SIS_2 PF13580.1 CEP10713.1 - 0.1 12.2 0.2 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 SIS domain GTP_EFTU PF00009.22 CEP10714.1 - 9.4e-47 158.8 0.0 2.3e-46 157.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEP10714.1 - 6.4e-24 84.0 0.6 2.9e-23 81.8 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEP10714.1 - 7.8e-11 41.9 0.1 1.7e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEP10714.1 - 0.00013 21.9 0.1 0.00041 20.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CEP10714.1 - 0.017 14.7 0.2 0.039 13.5 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Iso_dh PF00180.15 CEP10715.1 - 3.1e-83 279.5 0.0 3.8e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-CCHC PF00098.18 CEP10717.1 - 0.00052 19.8 2.6 0.00093 19.0 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 CEP10719.1 - 3.9e-19 68.8 0.0 4.8e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 CEP10720.1 - 1.7e-21 76.5 0.0 2.1e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP10720.1 - 7.4e-06 26.0 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 CEP10720.1 - 0.046 12.8 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease PIN_4 PF13638.1 CEP10721.1 - 1.3e-21 77.0 0.3 6.4e-21 74.8 0.1 2.4 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 CEP10721.1 - 7.3e-15 54.9 0.5 6.2e-14 51.8 0.4 2.3 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Utp12 PF04003.7 CEP10722.1 - 7.7e-19 67.6 0.0 1.5e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 CEP10722.1 - 4.3e-07 29.5 1.3 0.076 12.9 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat PLDc PF00614.17 CEP10723.1 - 6.1e-17 60.8 2.3 2.5e-10 39.8 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CEP10723.1 - 1.1e-13 50.9 0.1 2.8e-07 30.3 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain PUF PF00806.14 CEP10723.1 - 0.02 14.3 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Mg_trans_NIPA PF05653.9 CEP10725.1 - 4.1e-84 282.0 19.8 5e-84 281.8 13.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CEP10725.1 - 1.7e-06 28.0 5.7 1.7e-06 28.0 3.9 3.0 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 CEP10725.1 - 9.5e-05 22.5 0.7 9.5e-05 22.5 0.5 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Ycf66_N PF07444.6 CEP10725.1 - 5.7 6.7 11.4 3.7 7.3 0.5 3.6 2 2 3 5 5 5 0 Ycf66 protein N-terminus A2L_zn_ribbon PF08792.5 CEP10729.1 - 0.14 11.6 0.9 0.45 10.0 0.6 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain Helitron_like_N PF14214.1 CEP10730.1 - 4e-45 153.8 0.8 4.7e-44 150.3 0.0 2.7 3 0 0 3 3 3 1 Helitron helicase-like domain at N-terminus DnaJ_CXXCXGXG PF00684.14 CEP10730.1 - 0.087 12.8 7.5 2.8 8.0 0.5 2.7 1 1 1 2 2 2 0 DnaJ central domain zf-RING_3 PF14369.1 CEP10730.1 - 0.25 11.3 2.8 26 4.9 0.1 3.7 3 0 0 3 3 3 0 zinc-finger zf-CCHC PF00098.18 CEP10730.1 - 0.33 10.9 25.3 0.52 10.3 0.1 4.7 5 0 0 5 5 5 0 Zinc knuckle UvrD_C PF13361.1 CEP10733.1 - 1.7e-07 31.0 0.0 1.9e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HTH_28 PF13518.1 CEP10735.1 - 1.2e-05 25.1 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP10735.1 - 0.0015 18.6 0.1 0.0025 17.9 0.0 1.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 CEP10735.1 - 0.0023 17.5 0.3 0.0038 16.8 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CEP10735.1 - 0.01 14.9 0.1 0.026 13.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 PAX PF00292.13 CEP10735.1 - 0.039 13.6 0.0 0.056 13.1 0.0 1.3 1 1 0 1 1 1 0 'Paired box' domain PaaX PF07848.7 CEP10735.1 - 0.06 13.3 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein CENP-B_N PF04218.8 CEP10735.1 - 0.074 12.4 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.11 CEP10735.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 RasGEF PF00617.14 CEP10736.1 - 3.3e-46 157.4 1.6 7.9e-46 156.1 1.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEP10736.1 - 6.9e-15 55.0 7.4 4.3e-14 52.4 1.3 3.1 2 0 0 2 2 2 2 RasGEF N-terminal motif EF-hand_1 PF00036.27 CEP10737.1 - 3.4e-33 110.3 15.6 1.5e-08 33.3 0.3 4.7 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 CEP10737.1 - 1.1e-28 99.1 10.5 5.1e-16 58.5 1.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP10737.1 - 2.2e-25 86.1 9.7 2.9e-07 29.8 0.0 4.7 5 0 0 5 5 4 4 EF-hand domain EF-hand_5 PF13202.1 CEP10737.1 - 3.6e-24 82.9 15.3 5.4e-08 31.8 0.0 5.0 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 CEP10737.1 - 4.2e-20 71.1 16.9 3e-10 39.5 2.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CEP10737.1 - 1.4e-11 44.4 3.7 1.6e-06 28.0 0.3 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEP10737.1 - 1.9e-08 33.9 4.2 0.00067 19.3 0.7 2.7 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CEP10737.1 - 0.00011 22.0 0.4 0.65 9.9 0.0 2.8 2 1 1 3 3 3 3 EF-hand domain TerB PF05099.8 CEP10737.1 - 0.00051 19.7 0.3 0.72 9.5 0.0 2.6 2 1 1 3 3 3 2 Tellurite resistance protein TerB p25-alpha PF05517.7 CEP10737.1 - 0.002 18.3 0.4 0.002 18.3 0.3 2.7 2 1 2 4 4 4 1 p25-alpha Peptidase_S46 PF10459.4 CEP10737.1 - 0.097 11.0 3.3 0.57 8.5 0.2 2.0 1 1 1 2 2 2 0 Peptidase S46 EF-hand_10 PF14788.1 CEP10737.1 - 0.24 11.0 5.7 3.1 7.5 0.1 3.3 2 1 1 3 3 3 0 EF hand RNA_pol_Rpb1_5 PF04998.12 CEP10737.1 - 0.57 9.3 3.9 0.29 10.3 0.4 1.8 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 5 RVT_1 PF00078.22 CEP10739.1 - 4.2e-14 52.4 0.1 7.9e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Big_1 PF02369.11 CEP10741.1 - 0.0037 17.1 0.4 0.0046 16.8 0.3 1.3 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) Perilipin PF03036.11 CEP10742.1 - 1.6e-15 56.9 12.8 8.6e-14 51.1 8.9 2.3 1 1 0 1 1 1 1 Perilipin family Phasin PF05597.6 CEP10742.1 - 0.037 13.8 0.3 5.6 6.7 0.0 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.13 CEP10742.1 - 0.23 10.9 5.0 0.85 9.1 3.5 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3767 PF12597.3 CEP10743.1 - 2.9e-31 107.5 0.1 3.5e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) ATP-synt PF00231.14 CEP10744.1 - 9e-70 235.2 5.5 1e-69 235.0 3.8 1.0 1 0 0 1 1 1 1 ATP synthase ACT_4 PF13291.1 CEP10744.1 - 0.068 13.5 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 ACT domain zf-H2C2_2 PF13465.1 CEP10745.1 - 2.1e-09 37.2 10.9 6.2e-07 29.3 1.4 5.0 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEP10745.1 - 6.2e-09 35.6 28.0 0.00012 22.1 0.4 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP10745.1 - 2.2e-06 27.5 21.1 0.0051 17.0 0.2 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger MATH PF00917.21 CEP10745.1 - 0.19 11.9 3.3 0.33 11.2 0.6 2.5 2 0 0 2 2 2 0 MATH domain zf-TRAF PF02176.13 CEP10745.1 - 0.32 11.3 11.2 0.59 10.5 1.6 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger Aminotran_5 PF00266.14 CEP10746.1 - 6.9e-97 324.4 0.0 8.2e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CEP10746.1 - 1.5e-09 37.4 0.0 2.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CEP10746.1 - 1.9e-05 23.9 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CEP10746.1 - 0.00018 20.1 0.0 0.00028 19.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 CEP10746.1 - 0.0028 16.0 0.0 0.0045 15.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Tctex-1 PF03645.8 CEP10746.1 - 0.016 14.9 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Tctex-1 family Ribosomal_S24e PF01282.14 CEP10746.1 - 0.08 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S24e B12-binding PF02310.14 CEP10746.1 - 0.084 12.7 0.0 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain CsbD PF05532.7 CEP10747.1 - 1.6e-16 59.6 20.2 2e-10 40.1 4.0 2.0 1 1 1 2 2 2 2 CsbD-like Mrr_cat PF04471.7 CEP10747.1 - 0.1 12.3 0.9 0.15 11.8 0.2 1.5 1 1 1 2 2 2 0 Restriction endonuclease Endonuclease_5 PF04493.9 CEP10748.1 - 8.8e-59 198.3 0.0 1e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 CEP10748.1 - 0.009 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF99 NCA2 PF08637.5 CEP10749.1 - 8.2e-78 261.2 2.0 1.9e-77 260.0 1.4 1.6 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ion_trans PF00520.26 CEP10750.1 - 6e-87 290.0 69.3 9.6e-27 93.5 8.4 5.6 4 1 1 5 5 5 5 Ion transport protein DUF2419 PF10343.4 CEP10752.1 - 9.9e-27 93.9 0.0 2.1e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) HD_2 PF12917.2 CEP10752.1 - 0.072 12.8 0.2 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme E1-E2_ATPase PF00122.15 CEP10753.1 - 5.2e-61 205.6 6.7 5.2e-61 205.6 4.6 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CEP10753.1 - 2.6e-26 93.3 0.7 4.5e-26 92.5 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP10753.1 - 3.7e-14 53.3 0.0 8e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP10753.1 - 7e-13 47.8 0.0 1.7e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 CEP10753.1 - 0.0057 16.2 6.7 0.0057 16.2 4.6 2.7 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 CEP10753.1 - 0.019 14.5 0.1 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Chitin_synth_2 PF03142.10 CEP10754.1 - 9.4e-280 928.4 0.1 1.3e-279 928.0 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP10754.1 - 1.8e-19 70.1 0.5 4.9e-19 68.7 0.4 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP10754.1 - 1.5e-17 64.2 0.0 2.9e-16 59.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEP10754.1 - 0.00084 19.0 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP10754.1 - 0.00088 18.5 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 CEP10754.1 - 0.029 14.1 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Epimerase PF01370.16 CEP10755.1 - 2.3e-26 92.6 0.0 3.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CEP10755.1 - 4.1e-11 42.3 0.0 8.3e-11 41.3 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CEP10755.1 - 9.2e-11 40.9 0.0 1.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CEP10755.1 - 1e-07 32.1 0.0 5.7e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CEP10755.1 - 1.3e-05 24.2 0.2 0.00027 19.9 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 CEP10755.1 - 0.0096 14.9 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 CEP10755.1 - 0.0099 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CEP10755.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RhoGEF PF00621.15 CEP10757.1 - 1.5e-26 93.3 1.6 1.5e-26 93.3 1.1 2.0 2 0 0 2 2 2 1 RhoGEF domain GHMP_kinases_N PF00288.21 CEP10758.1 - 8.4e-13 48.1 0.8 2.1e-12 46.8 0.6 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CEP10758.1 - 5.3e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Imm29 PF15575.1 CEP10758.1 - 0.059 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 29 PHD PF00628.24 CEP10759.1 - 1.4e-08 34.2 14.8 2.4e-08 33.5 10.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEP10759.1 - 0.0016 17.6 9.1 0.0026 17.0 6.3 1.3 1 0 0 1 1 1 1 PHD-finger Cpn10 PF00166.16 CEP10759.1 - 0.13 12.2 0.5 0.69 9.8 0.1 2.2 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit NIPSNAP PF07978.8 CEP10760.1 - 9.6e-31 105.7 0.1 5.9e-23 80.7 0.0 2.6 2 1 0 2 2 2 2 NIPSNAP CBFD_NFYB_HMF PF00808.18 CEP10761.1 - 1.6e-18 66.5 0.4 2.9e-18 65.6 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEP10761.1 - 5.8e-06 26.3 0.2 9.9e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Menin PF05053.8 CEP10761.1 - 0.0011 17.2 6.0 0.0013 17.0 4.1 1.2 1 0 0 1 1 1 1 Menin TPT PF03151.11 CEP10762.1 - 5.9e-14 51.9 2.8 5.9e-14 51.9 1.9 2.5 1 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CEP10762.1 - 6e-11 41.8 17.5 7.6e-11 41.4 12.1 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP10762.1 - 0.0037 17.3 5.6 0.0037 17.3 3.9 2.5 2 1 0 2 2 2 1 EamA-like transporter family DUF2421 PF10334.4 CEP10763.1 - 6.7e-21 74.9 0.1 1.2e-20 74.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CEP10763.1 - 2.6e-16 59.5 13.2 2.6e-16 59.5 9.2 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CEP10763.1 - 3.7e-15 55.9 14.1 3.7e-15 55.9 9.8 3.4 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 CEP10763.1 - 2.1e-06 26.4 5.6 2.1e-06 26.4 3.9 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein family ALMT PF11744.3 CEP10763.1 - 9.4e-05 21.2 2.6 0.0003 19.5 1.8 1.8 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF3149 PF11346.3 CEP10763.1 - 0.0054 16.2 0.5 2.5 7.7 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3149) Asp PF00026.18 CEP10764.1 - 6.1e-62 209.6 0.1 1.3e-61 208.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP10764.1 - 2.1e-10 40.7 0.0 1.5e-08 34.7 0.1 3.4 3 2 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP10764.1 - 0.0033 16.9 0.0 0.032 13.7 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CEP10764.1 - 0.0039 17.6 1.8 0.038 14.4 0.1 3.0 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP10764.1 - 0.035 13.9 0.4 0.49 10.2 0.1 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.18 CEP10765.1 - 2.6e-75 253.6 0.5 1e-74 251.6 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP10765.1 - 5e-10 39.5 0.8 5.8e-09 36.1 0.1 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP10765.1 - 0.0015 18.1 0.1 0.0052 16.3 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 CEP10766.1 - 4e-73 246.4 1.6 5.5e-73 245.9 1.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP10766.1 - 1.7e-10 41.0 0.5 9.3e-10 38.6 0.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEP10766.1 - 0.012 16.0 1.8 2.3 8.7 0.0 3.5 3 1 1 4 4 4 0 Aspartyl protease TAXi_C PF14541.1 CEP10766.1 - 0.012 15.1 0.0 0.068 12.7 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal F-box-like PF12937.2 CEP10769.1 - 0.064 12.9 2.0 0.089 12.5 0.1 2.3 3 0 0 3 3 3 0 F-box-like DUF1498 PF07385.7 CEP10769.1 - 0.065 12.3 0.1 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) DUF743 PF05332.6 CEP10769.1 - 0.074 12.9 0.1 0.23 11.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF743) CBM49 PF09478.5 CEP10769.1 - 0.45 10.6 4.3 2.4 8.3 0.6 2.8 3 0 0 3 3 3 0 Carbohydrate binding domain CBM49 DUF1253 PF06862.7 CEP10770.1 - 7.7e-167 555.1 6.4 1.5e-166 554.2 4.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) UPF0052 PF01933.13 CEP10771.1 - 2e-51 175.1 0.0 2.7e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF1129 PF06570.6 CEP10772.1 - 0.034 13.4 0.2 0.034 13.4 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) SurA_N_3 PF13624.1 CEP10772.1 - 0.038 13.9 0.3 0.1 12.5 0.2 1.7 1 0 0 1 1 1 0 SurA N-terminal domain ABC_tran PF00005.22 CEP10773.1 - 3.1e-46 157.0 0.9 1.5e-22 80.3 0.0 3.3 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CEP10773.1 - 1.2e-22 79.4 5.3 1.2e-22 79.4 3.7 2.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CEP10773.1 - 6.1e-16 59.2 5.1 0.0078 16.2 0.0 5.1 6 0 0 6 6 5 4 AAA domain SMC_N PF02463.14 CEP10773.1 - 7.9e-12 44.8 3.7 0.0014 17.9 0.0 4.3 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CEP10773.1 - 2.3e-07 31.6 4.9 0.0056 17.4 0.0 4.3 5 1 0 5 5 3 2 AAA domain AAA_29 PF13555.1 CEP10773.1 - 2.5e-07 30.0 0.0 0.012 15.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP10773.1 - 2.6e-07 30.8 0.4 0.0069 16.3 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 CEP10773.1 - 7.8e-07 29.6 0.0 0.058 13.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CEP10773.1 - 9.2e-07 29.0 0.3 0.0083 16.2 0.0 3.4 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CEP10773.1 - 1.6e-06 28.0 0.0 0.044 13.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CEP10773.1 - 2.1e-06 27.0 0.0 0.0095 15.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 CEP10773.1 - 6.8e-06 26.1 0.4 0.12 12.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 CEP10773.1 - 2.3e-05 24.1 0.1 0.28 10.8 0.0 3.0 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CEP10773.1 - 2.8e-05 23.7 0.2 0.29 10.5 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain AAA_23 PF13476.1 CEP10773.1 - 3.2e-05 24.3 27.7 0.046 14.0 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 CEP10773.1 - 7.3e-05 22.6 0.9 0.18 11.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CEP10773.1 - 0.00011 22.4 10.7 0.11 12.8 0.0 5.1 5 1 0 5 5 4 2 AAA domain NACHT PF05729.7 CEP10773.1 - 0.00028 20.5 0.0 0.59 9.7 0.0 2.8 3 0 0 3 3 2 2 NACHT domain SbcCD_C PF13558.1 CEP10773.1 - 0.00098 18.9 0.7 0.028 14.3 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CEP10773.1 - 0.0014 18.5 2.9 0.94 9.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 CEP10773.1 - 0.0014 18.2 0.1 0.09 12.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CEP10773.1 - 0.0018 17.8 0.0 0.48 9.8 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 CEP10773.1 - 0.0022 16.7 0.0 1.4 7.6 0.0 2.4 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 CEP10773.1 - 0.0032 17.6 0.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 CEP10773.1 - 0.0044 17.2 0.1 5.1 7.2 0.0 3.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 CEP10773.1 - 0.0075 16.1 11.4 0.13 12.1 0.0 4.0 4 1 0 4 4 4 2 Dynamin family AAA_25 PF13481.1 CEP10773.1 - 0.0096 15.3 0.1 7.3 5.9 0.0 3.1 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.17 CEP10773.1 - 0.015 14.1 0.1 4.1 6.1 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.1 CEP10773.1 - 0.019 14.5 0.0 5.9 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CEP10773.1 - 0.036 13.6 0.7 2.9 7.3 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Arf PF00025.16 CEP10773.1 - 0.039 13.1 0.2 0.93 8.7 0.0 3.1 4 0 0 4 4 4 0 ADP-ribosylation factor family cobW PF02492.14 CEP10773.1 - 0.051 13.0 0.0 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CEP10773.1 - 0.064 12.9 0.1 11 5.6 0.0 2.7 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.20 CEP10773.1 - 0.096 12.1 0.0 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0184 PF03670.8 CEP10773.1 - 0.15 12.2 4.3 1.5 9.0 0.6 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) DUF87 PF01935.12 CEP10773.1 - 0.16 11.7 0.0 0.16 11.7 0.0 4.8 4 1 1 5 5 5 0 Domain of unknown function DUF87 Paf67 PF10255.4 CEP10774.1 - 2.2e-159 530.6 9.4 3.1e-159 530.2 6.5 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 CEP10774.1 - 0.0013 18.4 0.0 0.0087 15.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2042 PF09743.4 CEP10774.1 - 0.036 13.3 1.0 3.9 6.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2042) TPR_1 PF00515.23 CEP10774.1 - 0.059 12.9 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP10774.1 - 0.063 13.2 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 CEP10775.1 - 6.7e-74 249.0 0.0 2.5e-73 247.2 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 zf-RING_2 PF13639.1 CEP10775.1 - 1.3e-05 24.9 8.0 3e-05 23.7 5.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP10775.1 - 0.001 19.0 11.2 0.0028 17.6 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEP10775.1 - 0.014 15.5 6.8 0.014 15.5 4.7 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger DUF3450 PF11932.3 CEP10775.1 - 0.028 13.7 0.4 0.05 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 CEP10775.1 - 0.089 12.3 0.4 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 IncA protein zf-C3HC4 PF00097.20 CEP10775.1 - 0.17 11.5 11.4 0.4 10.3 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEP10775.1 - 0.39 10.6 6.3 1.5 8.7 4.4 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP10775.1 - 2.5 7.8 7.6 7.1 6.4 4.6 2.4 2 0 0 2 2 2 0 RING-type zinc-finger DUF4243 PF14027.1 CEP10776.1 - 2.1e-74 250.9 0.0 3.7e-74 250.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) DUF1910 PF08928.5 CEP10776.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) PRD PF00874.15 CEP10776.1 - 0.1 12.7 1.0 8.4 6.5 0.1 2.5 2 0 0 2 2 2 0 PRD domain BCDHK_Adom3 PF10436.4 CEP10777.1 - 3.5e-41 140.4 0.0 6.9e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CEP10777.1 - 9.8e-18 63.8 0.0 2.3e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2076 PF09849.4 CEP10777.1 - 0.00062 19.8 18.6 0.00062 19.8 12.9 2.1 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) HATPase_c_3 PF13589.1 CEP10777.1 - 0.0034 17.0 0.0 0.0081 15.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IATP PF04568.7 CEP10777.1 - 0.0036 17.2 3.0 0.0084 16.1 1.6 2.0 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HATPase_c_2 PF13581.1 CEP10777.1 - 0.016 15.0 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.1 CEP10777.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 GHKL domain zf-BED PF02892.10 CEP10778.1 - 4.7e-07 29.4 0.3 9.6e-07 28.4 0.2 1.5 1 0 0 1 1 1 1 BED zinc finger PIG-H PF10181.4 CEP10778.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component p450 PF00067.17 CEP10779.1 - 1.6e-54 185.1 0.0 2e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pam17 PF08566.5 CEP10780.1 - 6.4 6.4 8.5 0.19 11.3 1.2 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Pkinase PF00069.20 CEP10781.1 - 1.6e-21 76.6 0.0 2.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10781.1 - 1.2e-17 63.8 0.1 3.7e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3510 PF12022.3 CEP10781.1 - 0.11 12.5 3.9 8.3 6.5 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3510) Rad60-SLD PF11976.3 CEP10782.1 - 2.1e-20 72.1 2.2 9e-17 60.5 0.7 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF572 PF04502.8 CEP10782.1 - 0.034 13.3 0.5 0.034 13.3 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) hNIFK_binding PF12196.3 CEP10782.1 - 0.053 12.9 0.3 0.053 12.9 0.2 2.4 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK ThiS PF02597.15 CEP10782.1 - 0.13 12.6 0.2 0.36 11.2 0.2 1.7 1 0 0 1 1 1 0 ThiS family PBP PF01161.15 CEP10783.1 - 9.8e-17 61.1 0.1 2.2e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein rve PF00665.21 CEP10785.1 - 4.5e-14 52.5 0.0 9.5e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP10785.1 - 8.9e-12 44.5 1.7 1.3e-10 40.8 0.3 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP10785.1 - 0.008 15.5 0.2 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 CEP10785.1 - 0.034 13.8 2.6 0.14 11.9 0.1 2.9 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain DUF4220 PF13968.1 CEP10787.1 - 0.14 11.1 1.2 0.21 10.6 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Glyco_hydro_18 PF00704.23 CEP10788.1 - 6.1e-76 256.0 4.8 7.1e-76 255.8 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 CEP10789.1 - 3.1e-34 116.1 1.3 4e-34 115.8 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CEP10789.1 - 4e-29 99.9 11.7 6.6e-29 99.2 8.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CEP10789.1 - 4.6e-20 71.0 0.8 7.3e-20 70.4 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEP10789.1 - 9.9e-06 25.7 0.2 3.5e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CEP10789.1 - 0.00049 19.8 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 CEP10789.1 - 0.017 15.3 0.1 0.018 15.2 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEP10789.1 - 0.023 14.5 0.0 0.037 13.9 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 CEP10789.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 CEP10789.1 - 0.2 11.4 2.0 1.1 9.1 1.4 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Clathrin PF00637.15 CEP10790.1 - 3.6e-24 84.9 6.5 4.1e-24 84.7 0.5 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 CEP10790.1 - 4.9e-09 35.7 0.0 2.9e-06 26.9 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Vps39_2 PF10367.4 CEP10790.1 - 0.00017 21.7 0.7 0.0006 19.9 0.1 2.2 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.2 CEP10790.1 - 0.0013 18.7 2.6 0.0031 17.5 1.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CEP10790.1 - 0.0016 18.1 2.0 0.0037 17.0 1.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP10790.1 - 0.27 10.9 7.5 0.62 9.7 2.4 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP10790.1 - 0.32 10.7 8.5 0.015 14.9 1.9 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Polysacc_synt_4 PF04669.8 CEP10791.1 - 6.8e-23 81.0 2.2 2.4e-21 75.9 1.5 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Sushi PF00084.15 CEP10791.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Sushi domain (SCR repeat) DAO PF01266.19 CEP10792.1 - 6.8e-53 179.8 0.0 8.4e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP10792.1 - 7.3e-05 22.7 0.1 0.00019 21.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CEP10792.1 - 0.00035 19.7 0.1 0.035 13.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CEP10792.1 - 0.00046 19.3 0.0 0.0009 18.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CEP10792.1 - 0.00048 20.2 0.2 0.0036 17.4 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEP10792.1 - 0.00093 19.1 0.9 0.0096 15.8 0.7 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP10792.1 - 0.0044 16.0 0.1 0.0077 15.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Mqo PF06039.10 CEP10792.1 - 0.0073 14.5 0.0 0.055 11.6 0.0 2.0 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 CEP10792.1 - 0.01 14.6 0.2 0.021 13.6 0.1 1.5 1 1 0 1 1 1 0 FAD binding domain Reprolysin_4 PF13583.1 CEP10792.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NAD_binding_9 PF13454.1 CEP10792.1 - 0.047 13.4 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CEP10792.1 - 0.069 13.4 0.1 0.23 11.7 0.1 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 CEP10792.1 - 0.076 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 CEP10792.1 - 0.087 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CEP10792.1 - 0.09 11.3 0.2 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Saccharop_dh PF03435.13 CEP10792.1 - 0.093 11.6 0.4 0.26 10.2 0.1 1.9 3 0 0 3 3 3 0 Saccharopine dehydrogenase DDE_3 PF13358.1 CEP10793.1 - 9.2e-32 109.8 0.0 1.6e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.13 CEP10793.1 - 1.3e-05 24.8 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_29 PF13551.1 CEP10793.1 - 3.3e-05 23.9 0.0 7.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP10793.1 - 0.0038 17.9 0.0 0.014 16.1 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain rve PF00665.21 CEP10793.1 - 0.0075 16.3 0.0 0.079 13.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.1 CEP10793.1 - 0.0097 15.5 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CEP10793.1 - 0.028 13.5 0.0 0.066 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF4322 PF14210.1 CEP10793.1 - 0.046 13.1 0.3 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) Ras PF00071.17 CEP10794.1 - 6.6e-37 126.3 0.0 7.3e-37 126.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP10794.1 - 4.1e-08 33.7 0.0 7.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CEP10794.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CEP10794.1 - 0.012 14.8 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family CI-B14_5a PF07347.7 CEP10795.1 - 0.035 13.8 0.2 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) TPR_10 PF13374.1 CEP10795.1 - 0.52 10.3 2.3 1.4 8.9 0.7 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Velvet PF11754.3 CEP10796.1 - 1.7e-38 132.2 0.0 2.9e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Velvet factor CAP_N PF01213.14 CEP10797.1 - 3.1 7.0 18.0 0.021 14.0 6.5 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal LRR_4 PF12799.2 CEP10799.1 - 1e-17 63.3 25.1 7.3e-10 38.2 1.0 3.7 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP10799.1 - 1.9e-16 59.5 12.2 6.7e-08 32.1 0.9 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CEP10799.1 - 2.3e-13 48.1 18.8 0.042 13.8 0.2 5.8 6 0 0 6 6 6 5 Leucine Rich Repeat LRR_7 PF13504.1 CEP10799.1 - 1.6e-09 36.4 21.9 0.084 13.1 0.4 5.6 5 0 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 CEP10799.1 - 0.00033 20.4 20.5 0.4 10.8 0.3 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.1 CEP10799.1 - 0.00037 20.0 4.4 0.021 14.4 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat Zds_C PF08632.5 CEP10800.1 - 9.7e-23 79.3 0.4 9.7e-23 79.3 0.3 2.2 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zein PF01559.11 CEP10800.1 - 0.0018 17.6 0.1 0.0018 17.6 0.1 2.5 3 0 0 3 3 3 1 Zein seed storage protein O-FucT PF10250.4 CEP10801.1 - 6.1e-11 42.0 0.1 2.9e-06 26.6 0.0 2.7 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase AAA PF00004.24 CEP10802.1 - 1.3e-79 264.8 0.1 9e-46 155.3 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEP10802.1 - 1.2e-14 53.9 0.0 7e-08 31.8 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEP10802.1 - 9.1e-12 45.3 3.1 8.7e-07 29.0 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CEP10802.1 - 1.5e-11 44.5 0.6 1.3e-05 25.3 0.1 4.5 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CEP10802.1 - 2.4e-10 40.3 0.5 2.4e-05 24.1 0.1 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CEP10802.1 - 2.4e-10 41.2 0.0 2.7e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CEP10802.1 - 3.4e-09 35.9 1.3 8.2e-05 21.4 0.0 2.9 3 0 0 3 3 3 2 TIP49 C-terminus AAA_2 PF07724.9 CEP10802.1 - 3.1e-08 33.7 0.8 9.4e-06 25.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CEP10802.1 - 3.5e-08 33.4 0.1 0.00014 21.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CEP10802.1 - 1e-07 31.5 0.0 0.0039 16.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 CEP10802.1 - 2.9e-07 29.7 0.0 0.0014 17.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 CEP10802.1 - 1.4e-06 28.4 0.0 0.19 11.8 0.0 3.5 3 0 0 3 3 3 2 RNA helicase AAA_25 PF13481.1 CEP10802.1 - 1.5e-06 27.7 0.6 0.23 10.8 0.0 3.5 2 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CEP10802.1 - 2e-06 27.1 0.4 0.072 12.2 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CEP10802.1 - 2.6e-06 27.5 0.0 0.0045 17.0 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 CEP10802.1 - 8.6e-06 25.6 0.0 0.0002 21.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CEP10802.1 - 5.3e-05 22.8 4.2 0.0035 17.0 0.2 3.5 3 0 0 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 CEP10802.1 - 8.1e-05 22.9 0.0 0.012 15.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CEP10802.1 - 0.00014 21.0 1.0 0.31 10.1 0.0 3.6 3 1 0 3 3 3 2 KaiC Sigma54_activat PF00158.21 CEP10802.1 - 0.00016 21.1 0.2 0.14 11.5 0.0 3.7 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_28 PF13521.1 CEP10802.1 - 0.00035 20.5 3.3 0.036 14.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.6 CEP10802.1 - 0.00056 19.5 0.0 1.6 8.3 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CEP10802.1 - 0.00067 18.4 0.0 0.1 11.2 0.0 2.9 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 CEP10802.1 - 0.00087 19.5 2.2 0.25 11.6 0.0 3.4 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.7 CEP10802.1 - 0.0016 18.1 0.9 6 6.4 0.0 3.8 4 0 0 4 4 4 0 NACHT domain CDC48_N PF02359.13 CEP10802.1 - 0.0016 18.3 0.0 0.0064 16.4 0.0 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain ResIII PF04851.10 CEP10802.1 - 0.0022 17.8 0.5 0.046 13.5 0.0 2.8 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 CEP10802.1 - 0.0025 16.7 0.0 0.057 12.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 CEP10802.1 - 0.0029 17.2 0.2 0.59 9.7 0.0 2.8 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CEP10802.1 - 0.005 16.1 0.4 0.31 10.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Parvo_NS1 PF01057.12 CEP10802.1 - 0.0071 15.2 0.0 0.47 9.2 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 CEP10802.1 - 0.014 14.9 0.0 0.53 9.7 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CEP10802.1 - 0.027 14.2 0.5 5.7 6.6 0.0 3.5 2 1 1 3 3 3 0 NTPase AAA_24 PF13479.1 CEP10802.1 - 0.048 13.2 5.1 1.7 8.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain IPT PF01745.11 CEP10802.1 - 0.067 12.3 4.3 0.26 10.4 0.0 3.0 3 0 0 3 3 3 0 Isopentenyl transferase zf-C2H2_jaz PF12171.3 CEP10803.1 - 0.062 13.4 0.3 0.062 13.4 0.2 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding LIM PF00412.17 CEP10803.1 - 0.16 12.0 3.4 11 6.1 0.1 2.5 2 0 0 2 2 2 0 LIM domain zf-met2 PF12907.2 CEP10803.1 - 0.74 9.8 2.8 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding zf-C2H2 PF00096.21 CEP10803.1 - 2.2 8.7 9.0 0.4 11.1 0.4 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type Retrotrans_gag PF03732.12 CEP10806.1 - 2.2e-08 34.0 0.5 1.7e-06 28.0 0.1 2.4 2 0 0 2 2 2 2 Retrotransposon gag protein DDE_3 PF13358.1 CEP10807.1 - 7.9e-19 67.8 0.0 1.1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP10807.1 - 0.03 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain GAT PF03127.9 CEP10808.1 - 0.11 12.4 1.2 0.17 11.8 0.8 1.2 1 0 0 1 1 1 0 GAT domain LRR_8 PF13855.1 CEP10809.1 - 0.068 12.9 0.3 0.31 10.8 0.2 2.1 1 1 0 1 1 1 0 Leucine rich repeat UvrD_C_2 PF13538.1 CEP10810.1 - 0.0015 18.6 0.2 0.048 13.8 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain Mit_KHE1 PF10173.4 CEP10811.1 - 0.005 16.7 1.4 0.076 12.8 1.0 2.0 1 1 0 1 1 1 1 Mitochondrial K+-H+ exchange-related TBX PF12598.3 CEP10812.1 - 0.11 12.8 0.7 0.16 12.3 0.5 1.3 1 0 0 1 1 1 0 T-box transcription factor HDV_ag PF01517.13 CEP10813.1 - 0.11 12.1 3.1 5.2 6.7 0.1 2.2 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen MORN PF02493.15 CEP10813.1 - 2.9 7.8 11.9 3.1 7.7 0.1 4.0 4 0 0 4 4 4 0 MORN repeat Senescence PF06911.7 CEP10814.1 - 1.6e-24 86.5 4.2 3.6e-24 85.4 2.9 1.6 1 0 0 1 1 1 1 Senescence-associated protein Zw10 PF06248.8 CEP10815.1 - 1.8e-43 148.6 0.3 2.9e-36 124.7 0.3 2.1 1 1 1 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 CEP10815.1 - 9.3e-09 34.8 1.7 1.6e-08 34.0 0.0 2.1 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Sec8_exocyst PF04048.9 CEP10815.1 - 0.00084 18.9 10.2 0.013 15.1 6.1 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 CEP10815.1 - 0.0026 17.6 7.1 0.0071 16.2 4.9 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 CEP10815.1 - 0.025 13.4 4.7 0.046 12.6 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Prominin PF05478.6 CEP10815.1 - 0.074 10.5 3.1 9.5 3.6 3.1 2.1 2 0 0 2 2 2 0 Prominin AreA_N PF07573.6 CEP10816.1 - 0.059 13.9 1.5 0.09 13.3 0.5 1.7 1 1 1 2 2 2 0 Nitrogen regulatory protein AreA N terminus Uds1 PF15456.1 CEP10817.1 - 2.3e-18 66.3 10.3 2.3e-18 66.3 7.2 5.3 4 3 1 5 5 5 1 Up-regulated During Septation Rhodanese PF00581.15 CEP10817.1 - 4.4e-09 36.6 0.0 2.3e-08 34.3 0.0 2.3 1 0 0 1 1 1 1 Rhodanese-like domain PV-1 PF06637.6 CEP10818.1 - 0.017 13.7 0.3 0.02 13.4 0.2 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) MMtag PF10159.4 CEP10821.1 - 0.053 13.5 4.2 0.11 12.6 2.9 1.5 1 0 0 1 1 1 0 Kinase phosphorylation protein Zn_Tnp_IS1595 PF12760.2 CEP10821.1 - 0.057 13.2 8.4 1.2 9.0 0.8 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PHD PF00628.24 CEP10821.1 - 0.3 10.8 7.9 4.1 7.1 1.5 3.0 2 1 0 2 2 2 0 PHD-finger Tim54 PF11711.3 CEP10821.1 - 0.67 8.4 5.5 1.1 7.8 3.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nudix_N_2 PF14803.1 CEP10821.1 - 0.84 9.3 5.0 3.1 7.5 0.5 2.6 2 1 0 2 2 2 0 Nudix N-terminal zf-CHY PF05495.7 CEP10821.1 - 1.5 9.0 12.5 19 5.4 3.8 3.4 2 2 0 2 2 2 0 CHY zinc finger Rota_VP2 PF05087.7 CEP10821.1 - 2.1 6.1 6.3 2.5 5.8 4.4 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF3133 PF11331.3 CEP10821.1 - 3.7 7.1 9.9 1.1 8.8 1.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3133) C1_4 PF07975.7 CEP10821.1 - 5.6 7.0 13.6 6.7 6.7 1.5 4.0 2 2 1 3 3 3 0 TFIIH C1-like domain Exo_endo_phos_2 PF14529.1 CEP10822.1 - 0.0044 16.6 1.0 0.01 15.4 0.1 2.1 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase DUF3450 PF11932.3 CEP10823.1 - 0.056 12.7 0.3 0.066 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4140 PF13600.1 CEP10823.1 - 0.12 12.8 0.4 0.17 12.3 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) COPI_assoc PF08507.5 CEP10824.1 - 0.00015 21.4 0.1 0.00018 21.2 0.1 1.1 1 0 0 1 1 1 1 COPI associated protein ABC_membrane_2 PF06472.10 CEP10826.1 - 8.7e-94 313.7 3.4 1.2e-93 313.3 2.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CEP10826.1 - 6e-19 68.7 0.0 2.3e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CEP10826.1 - 8.5e-05 22.6 0.0 0.00024 21.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CEP10826.1 - 0.0019 17.4 0.1 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbmA_BacA PF05992.7 CEP10826.1 - 0.0083 15.3 0.5 0.015 14.5 0.4 1.3 1 0 0 1 1 1 1 SbmA/BacA-like family Adeno_IVa2 PF02456.10 CEP10826.1 - 0.037 12.6 0.0 0.061 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_23 PF13476.1 CEP10826.1 - 0.042 14.1 4.8 0.27 11.5 3.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CEP10826.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4042 PF13251.1 CEP10827.1 - 6.3e-36 123.5 4.6 1.9e-34 118.6 0.6 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.1 CEP10827.1 - 1.6e-12 47.5 0.1 1.7e-05 24.9 0.1 5.6 4 2 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 CEP10827.1 - 7.1e-12 45.4 8.3 0.002 18.5 0.7 8.1 8 1 1 9 9 9 3 HEAT-like repeat HEAT PF02985.17 CEP10827.1 - 3e-11 42.3 20.1 0.0032 17.4 0.2 8.7 9 0 0 9 9 9 5 HEAT repeat ATP11 PF06644.6 CEP10828.1 - 6.8e-66 222.4 4.0 8.1e-66 222.2 2.8 1.1 1 0 0 1 1 1 1 ATP11 protein 60KD_IMP PF02096.15 CEP10829.1 - 9.2e-46 156.0 2.6 9.2e-46 156.0 1.8 1.9 1 1 1 2 2 2 1 60Kd inner membrane protein HATPase_c PF02518.21 CEP10830.1 - 4.2e-29 100.4 0.1 1.5e-28 98.7 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEP10830.1 - 7.2e-20 71.0 0.3 3.4e-18 65.6 0.0 3.9 5 0 0 5 5 4 1 Response regulator receiver domain HisKA PF00512.20 CEP10830.1 - 1.3e-18 66.7 1.2 6.7e-18 64.4 0.0 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 CEP10830.1 - 5.9e-17 61.6 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 CEP10830.1 - 6.5e-11 42.5 3.5 2.4e-10 40.7 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain Pkinase_Tyr PF07714.12 CEP10830.1 - 6.6e-10 38.4 0.0 1.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_2 PF13185.1 CEP10830.1 - 2.5e-06 28.0 0.0 6.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.1 CEP10830.1 - 8.7e-05 22.6 0.0 0.0045 17.1 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP10830.1 - 0.0013 19.5 0.1 0.012 16.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 CEP10830.1 - 0.0026 16.6 0.1 0.2 10.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 CEP10830.1 - 0.0039 16.9 0.1 0.03 13.9 0.1 2.4 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 CEP10830.1 - 0.0076 16.5 0.0 0.031 14.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 CEP10830.1 - 0.021 14.4 0.6 0.21 11.2 0.4 2.5 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 CEP10830.1 - 0.025 14.4 0.1 0.85 9.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain GAF PF01590.21 CEP10830.1 - 0.035 14.2 0.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 GAF domain DUF258 PF03193.11 CEP10830.1 - 0.043 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CEP10830.1 - 0.067 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC1 PF03109.11 CEP10831.1 - 8.8e-33 112.8 0.1 2e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CEP10831.1 - 3.1e-05 23.8 0.0 0.0033 17.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 CEP10831.1 - 0.00043 19.5 0.1 0.0015 17.7 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) PI3_PI4_kinase PF00454.22 CEP10831.1 - 0.032 13.7 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase ADK PF00406.17 CEP10832.1 - 4.6e-13 49.3 0.2 3.2e-12 46.5 0.1 2.3 2 1 0 2 2 2 1 Adenylate kinase AAA_18 PF13238.1 CEP10832.1 - 0.14 12.5 1.2 1.4 9.2 0.8 2.4 1 1 0 1 1 1 0 AAA domain A_deaminase PF00962.17 CEP10833.1 - 6.5e-40 137.0 0.7 3e-29 102.0 0.1 2.1 1 1 1 2 2 2 2 Adenosine/AMP deaminase Oxysterol_BP PF01237.13 CEP10835.1 - 1.1e-81 274.1 0.0 1.4e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein BCNT PF07572.7 CEP10836.1 - 6e-22 77.3 5.1 6e-22 77.3 3.6 2.1 2 0 0 2 2 2 1 Bucentaur or craniofacial development DUF2457 PF10446.4 CEP10836.1 - 0.00087 18.1 19.6 0.0014 17.4 13.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) YL1 PF05764.8 CEP10836.1 - 0.002 17.7 22.4 0.002 17.7 15.5 1.4 2 0 0 2 2 2 1 YL1 nuclear protein TFIIF_alpha PF05793.7 CEP10836.1 - 0.02 13.3 25.9 0.025 12.9 18.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 CEP10836.1 - 0.034 12.6 21.0 0.045 12.2 14.5 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CEP10836.1 - 0.062 12.5 26.0 0.089 12.0 18.0 1.2 1 0 0 1 1 1 0 SDA1 Glyco_hydro_9 PF00759.14 CEP10837.1 - 1.6e-114 383.2 13.0 1.9e-114 383.0 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 FAA_hydrolase PF01557.13 CEP10838.1 - 1.3e-50 171.8 0.0 2.1e-50 171.1 0.0 1.2 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family tRNA-synt_His PF13393.1 CEP10840.1 - 3.1e-41 141.4 0.0 3.7e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CEP10840.1 - 1.3e-19 70.4 0.0 2.4e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEP10840.1 - 2.2e-13 49.9 0.1 5.5e-13 48.6 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CEP10840.1 - 3.4e-07 29.3 0.0 0.0014 17.4 0.0 2.9 3 1 0 3 3 3 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 CEP10840.1 - 0.00013 21.2 0.1 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.15 CEP10840.1 - 0.0034 16.6 0.0 0.15 11.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DEAD PF00270.24 CEP10842.1 - 6.6e-42 142.8 0.1 1.4e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CEP10842.1 - 5.8e-21 73.8 0.0 2.4e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CEP10842.1 - 1e-17 63.7 0.0 3.9e-17 61.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP10842.1 - 1.3e-06 28.3 0.0 1.3e-06 28.3 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEP10842.1 - 0.0019 18.3 0.1 0.0088 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF3287 PF11690.3 CEP10842.1 - 2.4 8.2 9.3 14 5.8 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF2372 PF10178.4 CEP10843.1 - 6e-08 32.7 0.0 9.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) HSF_DNA-bind PF00447.12 CEP10844.1 - 2.6e-37 127.1 2.6 2.6e-37 127.1 1.8 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding DUF4226 PF10774.4 CEP10844.1 - 0.02 14.8 0.2 0.041 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) TSA PF03249.8 CEP10844.1 - 1.7 7.0 4.1 2.9 6.3 2.9 1.3 1 0 0 1 1 1 0 Type specific antigen DUF544 PF04424.8 CEP10845.1 - 1.2e-28 99.3 0.0 8.4e-27 93.3 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF544) zf-CCCH PF00642.19 CEP10846.1 - 3.7e-11 42.4 25.3 9.3e-07 28.3 2.5 5.1 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pentapeptide PF00805.17 CEP10846.1 - 0.14 11.4 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) zf-CCCH_2 PF14608.1 CEP10846.1 - 6.2 6.9 12.4 0.13 12.3 0.8 3.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type PUF PF00806.14 CEP10847.1 - 1.6e-56 184.7 15.7 6.9e-09 34.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.19 CEP10847.1 - 0.028 14.1 0.7 0.081 12.6 0.5 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4381 PF14316.1 CEP10847.1 - 0.25 11.4 1.0 0.67 10.0 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Choline_transpo PF04515.7 CEP10848.1 - 2.4e-44 151.4 31.4 2.4e-44 151.4 21.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Milton PF12448.3 CEP10850.1 - 0.01 16.0 2.2 0.014 15.5 1.5 1.2 1 0 0 1 1 1 0 Kinesin associated protein DASH_Dad2 PF08654.5 CEP10850.1 - 0.018 15.0 0.7 0.018 15.0 0.5 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad2 PAT1 PF09770.4 CEP10850.1 - 0.025 12.8 13.4 0.025 12.8 9.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2076 PF09849.4 CEP10850.1 - 0.071 13.1 8.9 0.1 12.6 6.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.8 CEP10850.1 - 0.11 12.5 8.4 0.18 11.8 5.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3166 PF11365.3 CEP10850.1 - 0.13 12.7 0.7 0.84 10.1 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) TCP PF03634.8 CEP10850.1 - 0.51 10.7 6.9 0.9 9.9 4.8 1.3 1 0 0 1 1 1 0 TCP family transcription factor DivIC PF04977.10 CEP10850.1 - 2.2 7.8 7.4 0.35 10.3 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator vMSA PF00695.14 CEP10850.1 - 2.3 7.3 6.3 3.1 6.9 4.4 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus BORG_CEP PF14957.1 CEP10850.1 - 4.4 8.2 8.4 5.8 7.8 4.9 1.7 1 1 1 2 2 2 0 Cdc42 effector Chromo PF00385.19 CEP10851.1 - 9.1e-10 38.0 1.2 1.8e-09 37.1 0.8 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CEP10851.1 - 0.0028 17.7 0.0 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.3 CEP10851.1 - 0.03 14.0 1.9 0.039 13.6 0.1 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain DUF423 PF04241.10 CEP10852.1 - 1.4e-18 66.5 0.2 1.6e-18 66.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF423) NOA36 PF06524.7 CEP10853.1 - 0.09 12.0 6.0 0.1 11.8 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein Rpr2 PF04032.11 CEP10854.1 - 1.3 8.8 4.8 2.8 7.8 1.3 2.1 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Retrotrans_gag PF03732.12 CEP10855.1 - 0.024 14.7 0.4 0.082 12.9 0.1 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein Bromodomain PF00439.20 CEP10855.1 - 0.088 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Bromodomain FemAB PF02388.11 CEP10858.1 - 0.0018 17.0 0.6 0.0023 16.7 0.4 1.1 1 0 0 1 1 1 1 FemAB family FbpA PF05833.6 CEP10858.1 - 0.0025 16.4 0.5 0.0031 16.1 0.4 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Allexi_40kDa PF05549.6 CEP10858.1 - 0.0068 15.7 2.3 0.0085 15.4 1.6 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein DUF2968 PF11180.3 CEP10858.1 - 0.0073 15.7 5.9 0.011 15.1 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Spectrin PF00435.16 CEP10858.1 - 0.014 15.7 0.6 0.02 15.1 0.4 1.2 1 0 0 1 1 1 0 Spectrin repeat DivIVA PF05103.8 CEP10858.1 - 0.019 15.0 0.3 0.025 14.6 0.2 1.2 1 0 0 1 1 1 0 DivIVA protein Myc-LZ PF02344.10 CEP10858.1 - 0.02 14.4 1.3 0.034 13.7 0.9 1.3 1 0 0 1 1 1 0 Myc leucine zipper domain Med9 PF07544.8 CEP10858.1 - 0.02 14.5 1.1 0.033 13.9 0.8 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_27 PF13514.1 CEP10858.1 - 0.021 12.5 1.3 0.025 12.2 0.9 1.0 1 0 0 1 1 1 0 AAA domain Cluap1 PF10234.4 CEP10858.1 - 0.021 14.0 0.8 0.027 13.6 0.5 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF2630 PF10944.3 CEP10858.1 - 0.022 14.8 3.5 0.034 14.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) AIP3 PF03915.8 CEP10858.1 - 0.03 13.2 0.6 0.034 13.0 0.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 IncA PF04156.9 CEP10858.1 - 0.033 13.7 5.2 0.044 13.3 3.6 1.1 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 CEP10858.1 - 0.035 13.8 4.8 0.052 13.3 3.3 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4559 PF15112.1 CEP10858.1 - 0.036 13.2 0.5 0.044 12.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TEX12 PF15219.1 CEP10858.1 - 0.037 14.0 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed 12 NEMO PF11577.3 CEP10858.1 - 0.044 13.5 2.6 0.13 12.0 1.8 1.7 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO Spc24 PF08286.6 CEP10858.1 - 0.046 13.4 0.7 0.063 12.9 0.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF892 PF05974.7 CEP10858.1 - 0.047 13.5 0.7 0.061 13.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF972 PF06156.8 CEP10858.1 - 0.054 13.8 0.2 0.072 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 CEP10858.1 - 0.06 12.3 0.7 0.076 12.0 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1395 PF07160.7 CEP10858.1 - 0.065 12.7 0.8 0.097 12.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Tho2 PF11262.3 CEP10858.1 - 0.076 12.0 1.0 0.1 11.5 0.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Prp19 PF08606.6 CEP10858.1 - 0.14 11.8 1.7 0.19 11.4 0.7 1.5 2 0 0 2 2 1 0 Prp19/Pso4-like Cortex-I_coil PF09304.5 CEP10858.1 - 0.23 11.5 3.3 0.36 10.8 2.3 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil RVT_1 PF00078.22 CEP10860.1 - 2.2e-37 128.5 0.1 3.2e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 CEP10862.1 - 6.8e-19 68.0 0.0 1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP10862.1 - 0.00041 20.4 0.0 0.00088 19.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Helitron_like_N PF14214.1 CEP10863.1 - 2.9e-18 66.2 0.1 6.4e-18 65.1 0.0 1.6 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Ribosomal_L31e PF01198.14 CEP10863.1 - 0.006 16.2 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L31e DDE_3 PF13358.1 CEP10864.1 - 1.7e-05 24.6 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease TFIIA_gamma_C PF02751.9 CEP10864.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit DDE_3 PF13358.1 CEP10865.1 - 1.8e-10 40.7 0.0 2.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HLH PF00010.21 CEP10867.1 - 3.1e-14 52.4 1.3 1.1e-13 50.6 0.9 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Toxin_53 PF15532.1 CEP10867.1 - 0.21 11.8 1.6 0.35 11.1 0.4 2.0 2 0 0 2 2 2 0 Putative toxin 53 SLX9 PF15341.1 CEP10867.1 - 0.23 11.9 3.6 0.42 11.0 2.5 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 6PF2K PF01591.13 CEP10868.1 - 1.3e-78 263.1 0.2 1.7e-78 262.7 0.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEP10868.1 - 7.4e-23 81.3 0.0 1.5e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CEP10868.1 - 3.6e-05 23.6 0.0 5.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ribosomal_L27e PF01777.13 CEP10870.1 - 2.5e-37 126.8 6.7 3.8e-37 126.2 4.7 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CEP10870.1 - 9.8e-05 21.9 2.1 9.8e-05 21.9 1.5 2.0 2 0 0 2 2 2 1 KOW motif FKBP_C PF00254.23 CEP10871.1 - 2.6e-29 101.0 0.1 1.4e-28 98.7 0.0 2.2 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase RRM_1 PF00076.17 CEP10871.1 - 0.0088 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prothymosin PF03247.9 CEP10871.1 - 0.024 14.7 26.4 0.024 14.7 18.3 3.3 1 1 2 3 3 3 0 Prothymosin/parathymosin family Utp14 PF04615.8 CEP10871.1 - 0.085 11.0 37.6 0.11 10.5 26.1 1.1 1 0 0 1 1 1 0 Utp14 protein Mitofilin PF09731.4 CEP10871.1 - 0.76 8.3 23.8 1 7.9 16.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF572 PF04502.8 CEP10871.1 - 0.96 8.5 26.1 1.5 7.9 18.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mem_trans PF03547.13 CEP10871.1 - 1.9 6.6 3.8 3.2 5.9 2.6 1.4 1 0 0 1 1 1 0 Membrane transport protein CTC1 PF15489.1 CEP10871.1 - 3.5 4.8 4.3 2 5.6 1.8 1.4 2 0 0 2 2 2 0 CST, telomere maintenance, complex subunit CTC1 Ndc1_Nup PF09531.5 CEP10871.1 - 8.7 4.6 7.4 11 4.2 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Amidase PF01425.16 CEP10873.1 - 6.1e-119 397.7 0.1 2.5e-108 362.7 0.0 2.0 2 0 0 2 2 2 2 Amidase PyrI_C PF02748.10 CEP10874.1 - 0.2 11.1 2.3 4.6 6.7 0.2 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain OrfB_Zn_ribbon PF07282.6 CEP10874.1 - 0.21 11.2 2.2 0.64 9.7 1.6 1.9 1 1 0 1 1 1 0 Putative transposase DNA-binding domain RhoGAP PF00620.22 CEP10876.1 - 2.5e-45 153.8 1.9 4.6e-45 152.9 0.2 2.2 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CEP10876.1 - 2.8e-18 65.7 28.6 1.2e-09 38.1 4.7 2.7 2 0 0 2 2 2 2 LIM domain Erp_C PF06780.6 CEP10876.1 - 0.0084 15.9 1.9 0.0084 15.9 1.3 3.3 3 1 1 4 4 4 1 Erp protein C-terminus NYD-SP28_assoc PF14775.1 CEP10876.1 - 0.81 9.4 7.4 0.21 11.2 0.5 3.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain ELO PF01151.13 CEP10878.1 - 9.6e-70 234.7 9.9 1.1e-69 234.4 6.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family 4HBT PF03061.17 CEP10879.1 - 1.6e-06 28.1 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily WD40 PF00400.27 CEP10880.1 - 2.5e-05 23.9 10.6 0.26 11.2 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat RRM_1 PF00076.17 CEP10881.1 - 1.8e-15 56.3 0.1 2.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10881.1 - 2e-11 43.6 0.0 3.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10881.1 - 3e-10 39.7 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP10881.1 - 8.8e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Arrestin_C PF02752.17 CEP10882.1 - 1.5e-05 25.1 3.2 4.1e-05 23.6 0.4 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP10882.1 - 0.0003 20.6 3.2 0.0016 18.2 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 CEP10882.1 - 0.017 14.4 0.0 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 SpoOM protein zf-RING_2 PF13639.1 CEP10883.1 - 9.8e-16 57.3 6.2 9.8e-16 57.3 4.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CEP10883.1 - 1.9e-09 37.4 3.8 1.9e-09 37.4 2.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CEP10883.1 - 1.3e-08 34.4 6.3 1.3e-08 34.4 4.4 2.4 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_3 PF14369.1 CEP10883.1 - 9.9e-08 31.8 3.2 9.9e-08 31.8 2.3 2.6 3 0 0 3 3 3 1 zinc-finger zf-C3HC4_2 PF13923.1 CEP10883.1 - 1e-07 31.8 7.4 1e-07 31.8 5.1 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP10883.1 - 2.3e-07 30.3 4.7 2.3e-07 30.3 3.2 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP10883.1 - 4.7e-06 26.1 7.9 4.7e-06 26.1 5.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEP10883.1 - 0.00021 21.0 2.3 0.00053 19.7 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 CEP10883.1 - 0.0028 17.3 0.4 0.0067 16.1 0.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Rtf2 PF04641.7 CEP10883.1 - 0.003 16.8 2.0 0.003 16.8 1.4 1.9 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CEP10883.1 - 0.0042 16.7 4.7 0.0055 16.3 1.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger HypA PF01155.14 CEP10883.1 - 0.024 14.2 5.7 0.52 10.0 0.6 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family TraI_2 PF07514.6 CEP10883.1 - 0.035 12.8 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative helicase Prok-RING_1 PF14446.1 CEP10883.1 - 0.93 9.2 13.0 0.033 13.9 1.4 3.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 Baculo_RING PF05883.6 CEP10883.1 - 1.5 8.6 7.0 0.14 11.9 1.5 1.7 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF983 PF06170.7 CEP10883.1 - 2.8 8.1 3.8 28 4.8 0.1 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF983) Med13_C PF06333.7 CEP10884.1 - 1.6e-32 112.6 0.5 1.6e-32 112.6 0.4 5.4 4 2 0 4 4 4 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 CEP10884.1 - 3.1e-05 22.8 0.1 3.1e-05 22.8 0.1 4.0 3 1 1 4 4 4 2 Mediator complex subunit 13 N-terminal TFIIA PF03153.8 CEP10884.1 - 5.7 6.7 88.2 2.2 8.0 3.5 3.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Toxin_35 PF10530.4 CEP10885.1 - 0.1 12.6 0.8 0.17 11.9 0.6 1.5 1 1 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Antifungal_pept PF11410.3 CEP10885.1 - 0.48 10.5 3.9 0.78 9.8 2.7 1.4 1 0 0 1 1 1 0 Antifungal peptide DUF739 PF05339.6 CEP10886.1 - 0.043 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF739) DUF739 PF05339.6 CEP10887.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF739) Pap_E4 PF02711.9 CEP10887.1 - 2.1 9.2 7.4 0.37 11.6 2.3 1.8 1 1 1 2 2 2 0 E4 protein RRM_1 PF00076.17 CEP10888.1 - 2.6e-14 52.5 2.1 2.8e-10 39.6 0.2 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10888.1 - 1.1e-10 41.1 3.9 6.9e-09 35.4 0.1 3.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10888.1 - 5.2e-08 32.7 0.3 1.1e-05 25.3 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 CEP10888.1 - 0.0013 17.0 50.8 0.0056 14.9 28.7 2.2 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Iso_dh PF00180.15 CEP10889.1 - 4.9e-101 338.1 0.1 5.8e-101 337.9 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DBD_Tnp_Mut PF03108.10 CEP10890.1 - 0.0018 17.7 4.5 0.0041 16.6 1.7 2.6 2 1 0 2 2 2 1 MuDR family transposase Arginosuc_synth PF00764.14 CEP10891.1 - 2.2e-150 501.0 0.0 2.6e-150 500.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 CEP10891.1 - 0.0017 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CEP10891.1 - 0.037 12.5 0.0 0.056 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 CEP10891.1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase DDE_3 PF13358.1 CEP10892.1 - 2.5e-12 46.7 0.1 4.9e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF4240 PF14024.1 CEP10892.1 - 0.046 13.5 0.6 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) p450 PF00067.17 CEP10893.1 - 3.9e-70 236.6 0.2 4.9e-70 236.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cyclin PF08613.6 CEP10894.1 - 1.1e-07 32.3 0.1 1.6e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP10894.1 - 3e-06 26.8 0.2 6.8e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain E2 PF08199.6 CEP10894.1 - 0.1 12.1 0.7 2.2 7.9 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage E2-like protein RRS1 PF04939.7 CEP10895.1 - 3.4e-54 182.7 3.6 3.4e-54 182.7 2.5 1.8 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) IU_nuc_hydro PF01156.14 CEP10896.1 - 7.4e-13 48.3 0.0 8.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase zf-CCHC PF00098.18 CEP10898.1 - 2.7e-05 23.8 3.9 4.6e-05 23.1 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 CEP10898.1 - 0.0042 17.5 0.2 0.031 14.7 0.0 2.5 2 1 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP10898.1 - 0.087 12.6 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 CEP10899.1 - 1.7e-05 24.3 0.7 0.0005 19.4 0.1 2.4 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) THDPS_N_2 PF14805.1 CEP10899.1 - 0.042 13.7 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal rve PF00665.21 CEP10900.1 - 0.0012 18.8 0.0 0.0061 16.6 0.0 2.1 2 1 0 2 2 2 1 Integrase core domain HTH_22 PF13309.1 CEP10900.1 - 0.04 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 HTH domain rve PF00665.21 CEP10901.1 - 3.5e-08 33.5 0.0 1.6e-06 28.2 0.0 2.4 1 1 1 2 2 2 2 Integrase core domain Asp_protease_2 PF13650.1 CEP10902.1 - 0.045 14.2 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 CEP10902.1 - 0.35 10.8 2.6 0.93 9.5 1.8 1.8 1 0 0 1 1 1 0 Zinc knuckle Helitron_like_N PF14214.1 CEP10906.1 - 4.2e-40 137.4 0.0 5.1e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 CEP10912.1 - 3.8e-14 52.4 0.0 4.3e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase DUF2122 PF09895.4 CEP10912.1 - 0.045 13.9 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) PIF1 PF05970.9 CEP10913.1 - 1.4e-06 27.5 0.0 1.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase HTH_29 PF13551.1 CEP10915.1 - 1.1e-05 25.4 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP10915.1 - 0.0024 17.4 0.0 0.0079 15.8 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain DUF496 PF04363.7 CEP10915.1 - 0.0085 15.8 0.2 0.85 9.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF496) HTH_28 PF13518.1 CEP10915.1 - 0.045 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.2 CEP10915.1 - 0.047 13.9 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1804 PF08822.6 CEP10915.1 - 0.064 12.9 0.4 0.12 12.0 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1804) MerR_1 PF13411.1 CEP10915.1 - 0.08 12.7 2.6 0.11 12.2 0.0 2.6 4 0 0 4 4 4 0 MerR HTH family regulatory protein HTH_32 PF13565.1 CEP10915.1 - 0.13 13.1 0.1 0.31 11.8 0.0 1.8 1 1 0 1 1 1 0 Homeodomain-like domain DUF2052 PF09747.4 CEP10916.1 - 2.1e-30 105.9 25.5 2.1e-30 105.9 17.7 1.7 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Smac_DIABLO PF09057.5 CEP10916.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases HSF_DNA-bind PF00447.12 CEP10918.1 - 1.2e-34 118.5 1.0 1.2e-34 118.5 0.7 2.4 3 0 0 3 3 3 1 HSF-type DNA-binding Cdc6_C PF09079.6 CEP10918.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal RhoGEF PF00621.15 CEP10919.1 - 6.3e-19 68.5 1.6 6.3e-19 68.5 1.1 2.8 2 1 1 3 3 3 1 RhoGEF domain PH PF00169.24 CEP10919.1 - 0.00016 21.8 0.1 0.00072 19.7 0.1 2.2 1 1 0 1 1 1 1 PH domain PH_10 PF15411.1 CEP10919.1 - 0.23 11.6 3.4 0.43 10.7 0.0 3.2 3 1 1 4 4 4 0 Pleckstrin homology domain GFO_IDH_MocA PF01408.17 CEP10920.1 - 4.5e-21 75.5 1.1 1.3e-20 74.1 0.8 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 CEP10920.1 - 0.0011 19.0 0.2 0.002 18.2 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CEP10920.1 - 0.002 18.5 0.9 0.013 15.9 0.0 2.5 2 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_15 PF01793.11 CEP10921.1 - 6.4e-119 396.7 13.6 7.4e-119 396.5 9.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ank_2 PF12796.2 CEP10923.1 - 4.6e-17 62.1 2.8 5.3e-08 33.0 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEP10923.1 - 1.5e-16 59.2 2.0 5e-08 32.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CEP10923.1 - 2.3e-15 56.6 10.2 2.5e-05 24.6 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP10923.1 - 9.9e-15 54.2 2.6 0.0013 18.9 0.3 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP10923.1 - 1.3e-12 46.6 2.5 0.016 15.3 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat HTH_26 PF13443.1 CEP10925.1 - 0.072 13.3 0.1 0.66 10.2 0.0 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Cullin PF00888.17 CEP10928.1 - 2.6e-118 396.1 19.9 3.5e-118 395.7 13.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CEP10928.1 - 2.4e-21 75.3 1.4 1.1e-20 73.1 1.0 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.4 CEP10928.1 - 0.036 14.2 1.6 0.18 11.9 0.2 2.8 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal TRAPPC10 PF12584.3 CEP10929.1 - 5.8e-20 71.3 0.0 1.7e-19 69.8 0.0 1.8 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun PF07919.7 CEP10929.1 - 8.2e-05 21.1 1.9 0.014 13.7 0.0 2.5 2 1 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.2 CEP10929.1 - 0.0014 18.4 0.0 0.0039 16.9 0.0 1.8 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Foie-gras_1 PF11817.3 CEP10929.1 - 0.035 13.5 1.5 0.11 11.9 0.3 2.1 2 0 0 2 2 2 0 Foie gras liver health family 1 GATase_2 PF00310.16 CEP10930.1 - 4.5e-26 91.4 0.0 3.3e-21 75.4 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CEP10930.1 - 8.6e-17 61.3 0.0 1.8e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CEP10930.1 - 2.9e-14 52.8 0.0 6.3e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CEP10930.1 - 1e-09 38.1 0.2 2.1e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 CEP10930.1 - 5.5e-07 28.5 0.0 8.8e-07 27.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF2118 PF09891.4 CEP10930.1 - 0.023 14.4 1.5 0.22 11.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) Nro1 PF12753.2 CEP10931.1 - 1.4e-28 99.9 15.5 3e-22 79.1 0.3 2.3 1 1 1 2 2 2 2 Nuclear pore complex subunit Nro1 TPR_17 PF13431.1 CEP10931.1 - 0.00054 19.9 1.6 2.7 8.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP10931.1 - 0.0038 17.8 9.4 1.2 9.8 0.0 5.1 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP10931.1 - 0.0093 16.5 5.4 3.9 8.3 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat VitK2_biosynth PF02621.9 CEP10931.1 - 0.031 13.4 2.2 0.048 12.8 0.7 1.8 2 0 0 2 2 2 0 Menaquinone biosynthesis OMS28_porin PF03532.8 CEP10931.1 - 0.04 12.9 1.8 0.56 9.2 0.0 2.3 2 0 0 2 2 2 0 OMS28 porin SpoU_sub_bind PF08032.7 CEP10931.1 - 0.067 13.3 0.2 0.22 11.6 0.1 2.0 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding TPR_11 PF13414.1 CEP10931.1 - 0.25 11.0 12.3 1.9 8.1 0.0 5.3 3 2 3 6 6 6 0 TPR repeat TPR_19 PF14559.1 CEP10931.1 - 0.58 10.5 6.9 34 4.8 1.1 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP10931.1 - 1.3 8.9 12.1 11 6.0 0.4 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP10931.1 - 2.1 8.3 9.7 6.2 6.8 0.0 4.4 4 2 0 4 4 4 0 Tetratricopeptide repeat zinc-ribbons_6 PF07191.7 CEP10932.1 - 1.4 8.7 11.1 1 9.1 1.0 2.2 1 1 1 2 2 2 0 zinc-ribbons DUF3133 PF11331.3 CEP10932.1 - 2.3 7.8 0.0 2.3 7.8 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3133) Mu-like_Com PF10122.4 CEP10932.1 - 6 6.0 8.9 1.2 8.2 2.5 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com RPAP1_C PF08620.5 CEP10933.1 - 1.7e-24 85.4 4.4 1.5e-23 82.4 0.0 2.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CEP10933.1 - 1.1e-05 24.8 4.6 1.1e-05 24.8 3.2 2.2 2 0 0 2 2 2 1 RPAP1-like, N-terminal AAA PF00004.24 CEP10934.1 - 3.3e-06 27.3 0.2 0.00063 19.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CEP10934.1 - 0.013 14.1 0.3 1.1 7.8 0.0 3.0 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein RhoGAP PF00620.22 CEP10935.1 - 3.1e-35 121.0 0.1 1.3e-34 119.0 0.1 2.1 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CEP10935.1 - 5.5e-22 77.5 49.4 4.4e-11 42.6 6.7 5.1 4 1 0 4 4 4 4 LIM domain APC_CDC26 PF10471.4 CEP10935.1 - 0.0018 18.9 3.2 0.0018 18.9 2.2 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex APC subunit 1 PHF5 PF03660.9 CEP10935.1 - 2.6 8.1 27.8 0.16 12.0 8.1 3.4 2 1 0 2 2 2 0 PHF5-like protein Dishevelled PF02377.10 CEP10935.1 - 4.2 7.6 15.7 3 8.1 0.2 3.7 3 0 0 3 3 3 0 Dishevelled specific domain Dynamin_M PF01031.15 CEP10936.1 - 8.2e-104 346.5 0.1 4.3e-102 340.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CEP10936.1 - 1.1e-52 178.3 0.2 3.2e-52 176.7 0.1 1.9 1 0 0 1 1 1 1 Dynamin family VPS28 PF03997.7 CEP10936.1 - 5.5e-52 176.1 2.8 1.1e-51 175.1 2.0 1.5 1 0 0 1 1 1 1 VPS28 protein GED PF02212.13 CEP10936.1 - 3e-28 97.5 0.2 2.1e-27 94.8 0.1 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CEP10936.1 - 0.00011 22.1 0.5 0.0011 18.8 0.4 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Tim17 PF02466.14 CEP10937.1 - 3.8e-44 149.8 9.2 4.6e-44 149.5 6.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 CEP10937.1 - 0.065 13.3 6.9 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 CEP10937.1 - 1.5 8.5 8.7 5 6.8 1.4 2.3 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Aminotran_5 PF00266.14 CEP10938.1 - 1.6e-26 92.9 0.0 1.9e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.11 CEP10939.1 - 5e-36 124.1 29.4 5e-36 124.1 20.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CEP10939.1 - 0.017 15.1 0.5 0.017 15.1 0.3 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) RRM_1 PF00076.17 CEP10940.1 - 1.1e-17 63.3 0.2 1.7e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10940.1 - 2e-15 56.5 0.0 4.6e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10940.1 - 5.3e-10 39.0 0.0 9.2e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CEP10940.1 - 0.0005 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 CEP10940.1 - 0.007 16.1 0.1 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Corona_nucleoca PF00937.13 CEP10940.1 - 0.057 12.3 18.1 0.34 9.8 0.3 2.5 2 1 0 2 2 2 0 Coronavirus nucleocapsid protein CorA PF01544.13 CEP10940.1 - 0.15 11.0 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Nup35_RRM_2 PF14605.1 CEP10940.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 CEP10941.1 - 2.5e-40 138.2 0.0 4e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10941.1 - 3.8e-32 111.3 0.0 5.7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 CEP10941.1 - 6.1e-07 28.7 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain DUF2753 PF10952.3 CEP10941.1 - 0.0027 17.6 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) APH PF01636.18 CEP10941.1 - 0.0045 16.7 0.0 0.015 15.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family AP3B1_C PF14796.1 CEP10941.1 - 0.047 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Rho_N PF07498.7 CEP10941.1 - 0.052 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain RRM_1 PF00076.17 CEP10942.1 - 1.7e-15 56.4 0.2 1.6e-11 43.6 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10942.1 - 1.4e-12 47.3 0.2 8.6e-11 41.6 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10942.1 - 0.0037 17.0 0.3 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CHY PF05495.7 CEP10943.1 - 3.2e-13 49.6 17.4 3.2e-13 49.6 12.1 3.9 3 0 0 3 3 3 2 CHY zinc finger RWD PF05773.17 CEP10943.1 - 0.0001 22.1 0.1 0.022 14.6 0.0 2.6 2 0 0 2 2 2 2 RWD domain DASH_Dad1 PF08649.5 CEP10943.1 - 0.5 10.1 2.3 3.4 7.4 0.4 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad1 CLTH PF10607.4 CEP10944.1 - 3.5e-36 124.0 0.7 3.5e-36 124.0 0.5 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 CEP10944.1 - 1.2e-05 24.9 0.0 1.2e-05 24.9 0.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger YlqD PF11068.3 CEP10944.1 - 9.3 6.2 8.9 0.76 9.8 2.5 1.7 2 0 0 2 2 2 0 YlqD protein GATA PF00320.22 CEP10945.1 - 7.8e-31 105.1 13.6 2e-15 55.8 3.0 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 CEP10945.1 - 1.8e-10 40.1 1.0 5.1e-10 38.7 0.1 2.2 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 CEP10945.1 - 0.0034 16.6 3.7 0.52 9.6 0.2 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 CEP10945.1 - 0.029 14.1 10.3 0.8 9.5 0.6 3.2 2 1 1 3 3 3 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CEP10945.1 - 0.04 13.8 4.5 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 CEP10945.1 - 0.097 12.3 8.3 0.55 9.9 0.8 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 CEP10945.1 - 0.15 11.3 6.7 0.3 10.3 0.6 3.3 3 0 0 3 3 3 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.12 CEP10945.1 - 1.8 8.2 5.9 15 5.2 0.2 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 4HBT_3 PF13622.1 CEP10946.1 - 8.3e-29 101.0 0.0 9.7e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily FMN_red PF03358.10 CEP10947.1 - 3e-35 120.9 0.0 3.7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CEP10947.1 - 9.5e-12 44.8 0.1 1.4e-11 44.2 0.1 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold RRM_1 PF00076.17 CEP10948.1 - 5.8e-13 48.2 0.0 1.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP10948.1 - 5.2e-10 39.1 0.0 1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP10948.1 - 1.8e-08 34.1 0.0 3.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP10948.1 - 0.001 18.8 2.1 0.0028 17.4 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Lge1 PF11488.3 CEP10948.1 - 0.37 10.9 2.5 0.67 10.1 1.2 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Ubiquitin_2 PF14560.1 CEP10949.1 - 9.6e-27 93.0 0.0 1.9e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 CEP10949.1 - 2.9e-26 90.9 1.2 4.8e-26 90.2 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.18 CEP10949.1 - 0.0029 16.9 0.3 0.015 14.6 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family Homeobox PF00046.24 CEP10951.1 - 2.9e-14 52.4 2.3 2.9e-14 52.4 1.6 2.1 2 0 0 2 2 2 1 Homeobox domain HTH_23 PF13384.1 CEP10951.1 - 0.014 15.0 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox_KN PF05920.6 CEP10951.1 - 0.059 13.0 0.6 0.25 11.0 0.0 2.3 3 0 0 3 3 3 0 Homeobox KN domain DUF4451 PF14616.1 CEP10952.1 - 6e-24 84.1 0.8 2.1e-23 82.4 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) MAT1 PF06391.8 CEP10954.1 - 2.8e-43 147.8 28.7 5e-41 140.4 19.9 2.1 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 CEP10954.1 - 5e-07 29.3 8.3 3e-06 26.8 6.0 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP10954.1 - 1.4e-06 27.8 7.5 5.4e-06 25.9 5.3 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP10954.1 - 7e-06 25.6 6.1 2.2e-05 24.0 4.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP10954.1 - 7.2e-05 22.7 8.0 0.0003 20.7 5.8 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP10954.1 - 0.00052 19.7 9.4 0.00083 19.1 5.8 2.0 2 1 0 2 2 1 1 Ring finger domain zf-RING_4 PF14570.1 CEP10954.1 - 0.00054 19.4 4.1 0.039 13.5 0.9 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain GAGA PF09237.6 CEP10954.1 - 0.0027 17.2 9.4 0.023 14.2 0.8 3.4 3 0 0 3 3 3 1 GAGA factor RRN7 PF11781.3 CEP10954.1 - 0.033 13.6 1.1 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Phe_hydrox_dim PF07976.7 CEP10954.1 - 0.049 13.2 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain Selenoprotein_S PF06936.6 CEP10954.1 - 0.085 12.3 10.5 0.14 11.6 7.3 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Hom_end_hint PF05203.11 CEP10954.1 - 0.15 11.8 3.1 0.24 11.1 2.2 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint zf-rbx1 PF12678.2 CEP10954.1 - 0.2 11.8 2.9 0.48 10.5 2.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CEP10954.1 - 0.3 10.9 2.2 0.57 10.0 1.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CEP10954.1 - 0.41 10.4 8.0 0.34 10.6 1.5 2.6 2 0 0 2 2 2 0 RING-type zinc-finger U3_snoRNA_assoc PF08297.6 CEP10954.1 - 0.59 10.4 6.5 1.3 9.3 4.5 1.6 1 0 0 1 1 1 0 U3 snoRNA associated Mgr1 PF08602.5 CEP10954.1 - 0.72 8.7 4.7 1 8.3 3.3 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit NAD_binding_5 PF07994.7 CEP10954.1 - 5 6.5 5.9 8.7 5.7 4.1 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase zf-C3HC4_4 PF15227.1 CEP10954.1 - 8.9 6.2 11.9 63 3.5 7.1 3.1 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING SRP19 PF01922.12 CEP10955.1 - 6.8e-28 97.1 0.2 1.4e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 SRP19 protein Fork_head_N PF08430.7 CEP10955.1 - 0.16 12.3 15.2 0.079 13.3 8.5 1.8 2 0 0 2 2 2 0 Forkhead N-terminal region EMP24_GP25L PF01105.19 CEP10956.1 - 1.6e-37 128.9 1.6 2.2e-37 128.5 1.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 CEP10957.1 - 1.3e-55 188.3 0.0 2.6e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP10957.1 - 1e-20 73.9 0.0 1.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP10957.1 - 4.2e-05 23.3 0.1 0.0001 22.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP10957.1 - 0.0022 16.9 0.0 0.0048 15.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CEP10957.1 - 0.06 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CEP10957.1 - 0.34 10.4 6.4 0.75 9.3 0.1 2.6 3 0 0 3 3 3 0 Choline/ethanolamine kinase DUF1687 PF07955.6 CEP10958.1 - 1.2e-12 47.8 1.1 1.8e-12 47.3 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 CEP10958.1 - 2.1e-06 27.7 0.3 5.1e-06 26.5 0.2 1.8 1 1 0 1 1 1 1 ArsC family HTH_3 PF01381.17 CEP10958.1 - 0.018 14.8 0.0 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix Mgr1 PF08602.5 CEP10958.1 - 0.02 13.9 0.2 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Aconitase PF00330.15 CEP10959.1 - 1.1e-179 597.8 0.1 2.4e-179 596.6 0.1 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEP10959.1 - 1.6e-43 147.9 0.0 3.1e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain GCR1_C PF12550.3 CEP10960.1 - 0.0073 16.1 0.3 0.018 14.9 0.2 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF148 PF02520.12 CEP10960.1 - 0.088 12.6 0.8 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 OspE PF02471.12 CEP10961.1 - 0.074 12.9 0.4 4.1 7.3 0.0 2.5 2 1 0 2 2 2 0 Borrelia outer surface protein E MIS13 PF08202.6 CEP10962.1 - 1.8e-16 60.1 6.1 4.8e-16 58.7 4.3 1.6 1 1 0 1 1 1 1 Mis12-Mtw1 protein family RVT_1 PF00078.22 CEP10963.1 - 1.8e-07 30.7 0.1 8.9e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP10963.1 - 5.7e-07 29.7 1.8 1.3e-06 28.6 1.3 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Metallophos PF00149.23 CEP10964.1 - 2.5e-43 147.8 0.6 3.2e-43 147.4 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cwf21 PF08312.7 CEP10964.1 - 0.051 13.4 1.0 0.086 12.7 0.7 1.3 1 0 0 1 1 1 0 cwf21 domain Ribosomal_L1 PF00687.16 CEP10965.1 - 1.7e-35 122.3 1.3 2e-35 122.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Dynamin_N PF00350.18 CEP10966.1 - 4.1e-05 23.4 2.9 0.00024 20.9 2.0 2.3 1 1 0 1 1 1 1 Dynamin family Lge1 PF11488.3 CEP10966.1 - 0.04 14.1 3.8 4.4 7.5 0.7 3.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 HTH_Tnp_Tc3_2 PF01498.13 CEP10971.1 - 4.1e-10 39.5 0.2 1.7e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 CEP10971.1 - 3.9e-06 26.9 0.0 8.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Rap1-DNA-bind PF09197.5 CEP10971.1 - 0.093 13.2 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Rap1, DNA-binding fn2 PF00040.14 CEP10971.1 - 0.18 11.8 4.5 0.2 11.6 1.3 2.3 2 0 0 2 2 2 0 Fibronectin type II domain zf-CCHC PF00098.18 CEP10972.1 - 3.8e-06 26.5 4.3 6.9e-06 25.7 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CEP10972.1 - 0.011 15.2 0.7 0.021 14.3 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 CEP10972.1 - 0.041 13.6 0.4 0.066 12.9 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 CEP10972.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_6 PF15288.1 CEP10972.1 - 0.45 10.2 2.5 0.24 11.0 0.4 1.6 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 CEP10973.1 - 1.2e-10 41.1 1.3 1.2e-08 34.5 0.9 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP10974.1 - 2.7e-18 66.1 0.0 5.4e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP10974.1 - 0.035 13.6 0.5 0.077 12.5 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain F-box-like PF12937.2 CEP10975.1 - 3.8e-06 26.5 1.5 1.1e-05 25.0 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP10975.1 - 0.034 13.7 0.3 0.093 12.4 0.2 1.7 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 CEP10975.1 - 1.4 8.6 5.8 15 5.3 0.7 3.2 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) NTP_transf_2 PF01909.18 CEP10976.1 - 2.1e-07 31.1 0.0 1.1e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CEP10976.1 - 1.4e-05 24.8 0.1 3.9e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF2457 PF10446.4 CEP10976.1 - 2.1 6.9 13.9 3.5 6.2 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 CEP10976.1 - 3.7 5.3 17.0 5.8 4.6 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_trans_2_3 PF13632.1 CEP10977.1 - 6.4e-16 58.6 0.7 6.4e-16 58.6 0.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 PQ-loop PF04193.9 CEP10978.1 - 4.4e-28 96.5 7.3 4.6e-14 51.7 0.3 3.0 2 1 1 3 3 3 2 PQ loop repeat Thia_YuaJ PF09515.5 CEP10978.1 - 0.01 15.6 4.3 0.018 14.8 3.0 1.4 1 0 0 1 1 1 1 Thiamine transporter protein (Thia_YuaJ) MtN3_slv PF03083.11 CEP10978.1 - 0.023 14.5 5.4 0.12 12.2 0.3 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Radial_spoke PF04712.7 CEP10979.1 - 0.27 9.9 5.9 0.35 9.5 4.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PRK PF00485.13 CEP10980.1 - 7.5e-06 25.6 0.0 3.2e-05 23.5 0.0 2.0 2 1 1 3 3 3 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 CEP10980.1 - 0.00011 21.8 0.0 0.0006 19.5 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CEP10980.1 - 0.00015 22.5 0.0 0.00053 20.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CEP10980.1 - 0.00033 20.1 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 CEP10980.1 - 0.0015 18.8 0.0 0.0067 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP10980.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CEP10980.1 - 0.0019 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CEP10980.1 - 0.0027 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 CEP10980.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 CEP10980.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 CEP10980.1 - 0.0096 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 CEP10980.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CEP10980.1 - 0.01 15.3 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CEP10980.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 CEP10980.1 - 0.022 13.5 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein KAP_NTPase PF07693.9 CEP10980.1 - 0.025 13.5 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain UPF0079 PF02367.12 CEP10980.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CEP10980.1 - 0.038 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 CEP10980.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 CEP10980.1 - 0.055 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 CEP10980.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.7 CEP10980.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 CEP10980.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 CEP10980.1 - 0.092 12.6 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2414 PF10309.4 CEP10980.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) AAA_33 PF13671.1 CEP10980.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CEP10980.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PWWP PF00855.12 CEP10981.1 - 1.3e-16 60.5 0.0 1.3e-16 60.5 0.0 2.6 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 CEP10981.1 - 1.8e-07 30.5 0.0 3.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain MIP-T3 PF10243.4 CEP10981.1 - 0.013 14.0 44.6 0.016 13.6 30.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sugar_tr PF00083.19 CEP10983.1 - 7e-128 427.0 33.3 8.1e-128 426.8 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP10983.1 - 1e-26 93.5 57.9 1.3e-20 73.4 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 CEP10983.1 - 0.017 14.6 12.3 0.66 9.4 2.1 2.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 CBS PF00571.23 CEP10984.1 - 9.2e-29 98.9 3.0 5.7e-08 32.4 0.0 4.5 4 1 0 4 4 4 4 CBS domain IF3_N PF05198.11 CEP10984.1 - 0.099 12.5 0.1 3.7 7.5 0.0 2.9 2 1 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain FF PF01846.14 CEP10985.1 - 2.9e-32 110.3 15.6 2.8e-14 52.7 2.2 3.6 3 0 0 3 3 3 3 FF domain WW PF00397.21 CEP10985.1 - 2e-13 49.9 9.4 5.7e-08 32.4 2.5 2.6 2 0 0 2 2 2 2 WW domain DUF342 PF03961.8 CEP10985.1 - 3.7 5.8 11.3 6.5 5.0 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SNF2_N PF00176.18 CEP10987.1 - 5e-82 275.0 2.0 5e-82 275.0 1.4 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP10987.1 - 3.7e-19 68.3 0.0 2.3e-17 62.6 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 CEP10987.1 - 1.8e-16 59.6 9.7 1.8e-16 59.6 6.7 2.2 2 0 0 2 2 2 1 HSA SnAC PF14619.1 CEP10987.1 - 4.6e-15 55.5 1.0 4.6e-15 55.5 0.7 3.9 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 CEP10987.1 - 9.5e-10 37.7 5.6 9.5e-10 37.7 3.9 2.0 2 0 0 2 2 2 1 QLQ Bromodomain PF00439.20 CEP10987.1 - 2.7e-07 30.3 0.4 1.2e-06 28.2 0.2 2.2 1 1 0 1 1 1 1 Bromodomain ResIII PF04851.10 CEP10987.1 - 2.7e-06 27.3 0.0 2.7e-06 27.3 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CHU_C PF13585.1 CEP10987.1 - 0.057 13.2 0.2 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of CHU protein family Ribosomal_L1 PF00687.16 CEP10989.1 - 1.5e-49 168.3 1.3 1.8e-49 168.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Dynamin_N PF00350.18 CEP10990.1 - 1.7e-44 151.6 1.5 1e-43 149.0 0.0 2.9 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.15 CEP10990.1 - 4.4e-17 61.8 2.3 2.4e-14 52.8 0.1 2.8 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 CEP10990.1 - 2.9e-05 23.9 0.0 0.00054 19.9 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CEP10990.1 - 0.0017 18.8 0.3 0.0081 16.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 CEP10990.1 - 0.062 13.2 0.0 0.062 13.2 0.0 3.0 3 1 0 3 3 3 0 AAA domain HLH PF00010.21 CEP10991.1 - 9.5e-09 34.8 1.3 2.5e-08 33.5 0.9 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CK_II_beta PF01214.13 CEP10992.1 - 1.5e-74 249.5 0.0 1.8e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Phe_ZIP PF08916.6 CEP10992.1 - 0.13 12.6 0.2 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Phenylalanine zipper MMS19_N PF14500.1 CEP10993.1 - 3.8e-89 298.4 2.6 1.5e-87 293.2 0.0 3.7 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CEP10993.1 - 9.5e-87 291.3 10.2 9.5e-87 291.3 7.0 3.8 3 1 0 4 4 4 1 RNAPII transcription regulator C-terminal HEAT PF02985.17 CEP10993.1 - 0.0023 17.8 0.1 0.0023 17.8 0.1 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 CEP10993.1 - 0.017 15.5 12.1 0.02 15.3 0.3 5.5 4 2 1 5 5 5 0 HEAT-like repeat ParcG PF10274.4 CEP10993.1 - 0.062 13.1 0.8 0.27 11.1 0.1 2.5 2 0 0 2 2 2 0 Parkin co-regulated protein DUF1688 PF07958.6 CEP10994.1 - 6.1e-133 443.3 0.0 6.8e-133 443.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) bZIP_1 PF00170.16 CEP10995.1 - 1e-11 44.6 10.3 1e-11 44.6 7.1 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP10995.1 - 2e-05 24.3 3.8 2e-05 24.3 2.6 2.7 3 0 0 3 3 3 1 Basic region leucine zipper ACCA PF03255.9 CEP10995.1 - 0.0014 18.1 2.2 0.0029 17.1 1.5 1.5 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2216 PF10226.4 CEP10995.1 - 0.002 17.6 0.4 0.002 17.6 0.3 2.1 2 0 0 2 2 2 1 Uncharacterized conserved proteins (DUF2216) DUF1993 PF09351.5 CEP10995.1 - 0.08 12.8 2.8 0.18 11.7 1.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) Glutaredoxin2_C PF04399.8 CEP10995.1 - 0.15 11.6 1.8 0.35 10.4 1.3 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain tRNA-synt_1e PF01406.14 CEP10995.1 - 0.21 10.6 2.1 0.21 10.6 0.8 1.3 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SlyX PF04102.7 CEP10995.1 - 1.3 9.4 8.1 10 6.5 0.1 2.8 2 0 0 2 2 2 0 SlyX Dsh_C PF12316.3 CEP10995.1 - 1.3 9.0 15.1 0.31 11.1 5.4 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal SOBP PF15279.1 CEP10995.1 - 3.3 8.0 11.3 5.4 7.3 7.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PRELI PF04707.9 CEP10996.1 - 2e-45 154.1 0.2 2.5e-45 153.8 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family CcmH PF03918.9 CEP10998.1 - 0.036 13.0 0.1 0.047 12.6 0.1 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Flavi_glycoprot PF00869.15 CEP10998.1 - 0.1 11.5 0.3 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains Ogr_Delta PF04606.7 CEP10998.1 - 0.49 10.0 2.1 1.5 8.5 1.6 1.8 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger HA2 PF04408.18 CEP11000.1 - 1.8e-25 88.8 0.0 1.8e-25 88.8 0.0 2.8 3 0 0 3 3 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEP11000.1 - 1.7e-14 53.6 0.0 6.4e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEP11000.1 - 3.3e-13 49.2 0.0 1.1e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP11000.1 - 2.4e-08 33.6 0.1 6.5e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEP11000.1 - 4.4e-07 30.0 0.5 1.1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CEP11000.1 - 0.0025 16.7 0.0 0.0052 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 CEP11000.1 - 0.003 16.4 0.0 0.0068 15.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Flavi_DEAD PF07652.9 CEP11000.1 - 0.0056 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_10 PF12846.2 CEP11000.1 - 0.0063 15.9 0.7 1.6 8.0 0.0 2.6 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 CEP11000.1 - 0.0089 15.9 0.1 0.077 12.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CEP11000.1 - 0.0094 16.0 0.0 0.036 14.1 0.0 2.0 2 0 0 2 2 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 CEP11000.1 - 0.017 15.4 0.7 0.14 12.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF2477 PF10631.4 CEP11000.1 - 0.017 15.3 0.4 0.047 13.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) AAA_16 PF13191.1 CEP11000.1 - 0.019 14.9 0.0 0.084 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 CEP11000.1 - 0.029 13.8 0.3 0.078 12.4 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 CEP11000.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 CEP11000.1 - 0.078 13.3 0.0 0.078 13.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 CEP11000.1 - 0.078 12.6 0.1 0.98 9.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 CEP11000.1 - 0.12 12.1 7.3 4.1 7.2 0.0 3.7 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 CEP11001.1 - 7.6e-54 182.5 0.1 9.9e-54 182.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11001.1 - 1.9e-28 99.2 0.0 2.7e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP11001.1 - 2.8e-06 26.5 0.0 1e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 CEP11001.1 - 0.00084 18.2 0.4 0.0014 17.5 0.3 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase PIP49_C PF12260.3 CEP11001.1 - 0.056 12.8 0.1 0.056 12.8 0.0 2.0 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Kdo PF06293.9 CEP11001.1 - 0.091 11.8 0.3 0.15 11.0 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUDIX PF00293.23 CEP11002.1 - 1.4e-13 50.6 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 CEP11002.1 - 0.0028 17.0 0.0 0.0035 16.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase EMG1 PF03587.9 CEP11003.1 - 2.5e-46 157.5 0.0 4.3e-34 117.5 0.0 2.0 1 1 1 2 2 2 2 EMG1/NEP1 methyltransferase Peptidase_M16_C PF05193.16 CEP11004.1 - 6.2e-48 162.9 0.0 1e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CEP11004.1 - 3.8e-42 143.5 0.0 2.2e-41 141.0 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2076 PF09849.4 CEP11004.1 - 0.034 14.1 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribul_P_3_epim PF00834.14 CEP11006.1 - 2.1e-59 200.0 0.0 2.6e-38 131.1 0.1 2.0 1 1 1 2 2 2 2 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 CEP11006.1 - 0.0032 17.0 0.1 0.0063 16.0 0.0 1.6 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PucR PF07905.6 CEP11006.1 - 0.013 15.0 0.1 0.65 9.5 0.0 2.1 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family OMPdecase PF00215.19 CEP11006.1 - 0.024 14.0 0.1 0.051 12.9 0.0 1.4 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 CEP11006.1 - 0.04 13.1 0.2 0.059 12.6 0.1 1.5 1 1 0 1 1 1 0 PcrB family AMPKBI PF04739.10 CEP11007.1 - 5.9e-28 96.7 6.2 5.9e-28 96.7 4.3 2.6 2 1 1 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain Herpes_BLLF1 PF05109.8 CEP11007.1 - 1.7 6.5 47.3 2.3 6.0 32.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) GLTP PF08718.6 CEP11008.1 - 3e-40 137.6 0.0 4.5e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Mg_trans_NIPA PF05653.9 CEP11009.1 - 1.4e-25 89.8 13.4 3.4e-14 52.5 2.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CEP11009.1 - 4.9e-06 26.7 5.8 4.9e-06 26.7 4.0 3.1 2 2 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CEP11009.1 - 0.00049 20.1 9.9 0.00049 20.1 6.9 3.2 3 2 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 CEP11009.1 - 0.0041 16.7 2.2 0.0041 16.7 1.5 2.3 2 1 1 3 3 3 1 Triose-phosphate Transporter family DUF3185 PF11381.3 CEP11009.1 - 0.23 11.2 4.7 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) PBP1_TM PF14812.1 CEP11009.1 - 2.2 8.6 4.3 5.5 7.3 3.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4131 PF13567.1 CEP11009.1 - 7.6 5.9 15.7 2.1 7.7 1.7 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4131) Glyco_hydro_38 PF01074.17 CEP11010.1 - 1.7e-85 286.6 0.2 2.9e-85 285.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CEP11010.1 - 8.2e-78 262.2 0.1 1.1e-77 261.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CEP11010.1 - 9.4e-22 77.0 0.0 2.9e-21 75.4 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 CEP11010.1 - 1.2e-07 31.0 0.0 2.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF3603 PF12227.3 CEP11010.1 - 0.025 13.7 0.3 0.047 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) CUE PF02845.11 CEP11012.1 - 7.4e-09 34.9 0.0 1.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain SPRY PF00622.23 CEP11013.1 - 8.6e-13 48.4 0.1 1.3e-11 44.6 0.1 2.3 2 0 0 2 2 2 1 SPRY domain zf-C3HC4_3 PF13920.1 CEP11013.1 - 4e-10 39.1 1.5 7.6e-10 38.3 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP11013.1 - 0.0021 17.6 2.9 0.009 15.6 2.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP11013.1 - 0.0058 16.6 4.9 0.014 15.3 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP11013.1 - 0.22 11.2 3.4 0.46 10.2 2.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CEP11013.1 - 0.43 10.4 4.9 1.2 9.0 3.4 1.8 1 0 0 1 1 1 0 Ring finger domain Macoilin PF09726.4 CEP11013.1 - 2 6.6 13.5 0.078 11.2 4.4 1.9 2 0 0 2 2 2 0 Transmembrane protein DMAP_binding PF06464.6 CEP11013.1 - 5.3 7.6 11.9 1.2 9.7 3.2 2.4 2 0 0 2 2 2 0 DMAP1-binding Domain zf-LYAR PF08790.6 CEP11014.1 - 6.3e-15 54.5 5.6 1.4e-14 53.4 3.9 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger FTZ PF03867.9 CEP11014.1 - 0.0012 18.1 2.8 0.0037 16.5 1.5 1.8 2 0 0 2 2 2 1 Fushi tarazu (FTZ), N-terminal region UvrD-helicase PF00580.16 CEP11014.1 - 0.098 11.9 6.6 0.11 11.7 4.6 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain YjcQ PF09639.5 CEP11014.1 - 0.12 12.4 1.2 0.29 11.2 0.0 2.1 2 1 1 3 3 3 0 YjcQ protein Glyco_hydro_35 PF01301.14 CEP11014.1 - 0.13 11.6 2.2 0.18 11.1 1.5 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Arc_trans_TRASH PF08394.5 CEP11014.1 - 0.47 10.6 3.8 2.1 8.5 2.6 2.2 1 0 0 1 1 1 0 Archaeal TRASH domain BBS2_Mid PF14783.1 CEP11015.1 - 1.8e-07 30.8 0.2 0.0076 16.0 0.0 3.7 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.1 CEP11015.1 - 1.2e-05 25.5 0.5 0.00067 19.9 0.0 2.8 2 1 1 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CEP11015.1 - 6.8e-05 22.4 5.7 0.0038 16.8 0.0 4.1 4 0 0 4 4 4 1 FG-GAP repeat F-box-like PF12937.2 CEP11016.1 - 8.5e-09 34.9 0.4 2.3e-08 33.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP11016.1 - 1.6e-07 30.7 0.2 1.6e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 CEP11016.1 - 0.74 10.0 3.6 50 4.4 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 CEP11016.1 - 2.3 8.7 8.6 45 4.8 0.0 6.1 6 0 0 6 6 6 0 Leucine rich repeat Dna2 PF08696.6 CEP11017.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 DNA replication factor Dna2 Put_DNA-bind_N PF06971.8 CEP11018.1 - 0.17 11.6 1.4 4.3 7.1 0.0 3.1 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus DUF3510 PF12022.3 CEP11019.1 - 0.33 11.0 2.4 9.5 6.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) DUF3463 PF11946.3 CEP11020.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) APS_kinase PF01583.15 CEP11021.1 - 3.8e-71 237.8 0.0 4.6e-71 237.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CEP11021.1 - 2e-09 37.4 0.0 2.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP11021.1 - 8.9e-06 26.5 0.0 1.3e-05 25.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP11021.1 - 0.00043 20.5 0.1 0.00078 19.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CEP11021.1 - 0.00061 19.0 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 CEP11021.1 - 0.0014 18.0 0.1 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CEP11021.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.13 CEP11021.1 - 0.087 11.8 0.0 0.89 8.5 0.0 2.0 2 0 0 2 2 2 0 6-phosphofructo-2-kinase MobB PF03205.9 CEP11021.1 - 0.092 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 4HBT PF03061.17 CEP11022.1 - 7.6e-12 45.1 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 CEP11022.1 - 0.05 13.3 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.1 CEP11022.1 - 0.053 13.4 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Usg PF06233.7 CEP11022.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 Usg-like family HMG_box PF00505.14 CEP11023.1 - 8.2e-18 64.4 0.1 2.6e-17 62.8 0.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP11023.1 - 2.9e-11 43.5 0.0 6.1e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain bZIP_2 PF07716.10 CEP11023.1 - 0.053 13.3 2.5 0.18 11.6 1.4 2.2 1 1 1 2 2 2 0 Basic region leucine zipper CS PF04969.11 CEP11024.1 - 2.2e-09 37.7 0.4 4e-09 36.8 0.3 1.4 1 0 0 1 1 1 1 CS domain DUF2095 PF09868.4 CEP11025.1 - 0.0012 18.6 0.1 0.0014 18.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2095) GMC_oxred_N PF00732.14 CEP11026.1 - 1.4e-58 198.4 0.0 2.2e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEP11026.1 - 9.4e-32 110.2 0.1 1.8e-31 109.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CEP11026.1 - 4.2e-07 29.1 0.2 0.00019 20.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 CEP11026.1 - 6.1e-06 26.4 1.0 0.1 12.6 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP11026.1 - 4.1e-05 22.6 0.7 8.5e-05 21.6 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP11026.1 - 4.5e-05 23.3 0.1 0.00013 21.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP11026.1 - 0.00017 21.4 0.7 0.0028 17.5 0.1 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP11026.1 - 0.00058 18.8 0.1 0.00097 18.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CEP11026.1 - 0.023 14.4 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 CEP11026.1 - 0.028 13.5 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 CEP11026.1 - 0.06 11.8 0.4 0.18 10.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.1 CEP11026.1 - 0.06 12.2 0.0 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Malic_M PF03949.10 CEP11026.1 - 0.077 12.5 0.6 0.28 10.7 0.8 1.6 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 CEP11026.1 - 0.081 13.3 0.1 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pex24p PF06398.6 CEP11027.1 - 0.16 10.7 2.8 0.076 11.7 0.1 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Urotensin_II PF02083.10 CEP11027.1 - 0.62 9.5 3.0 1.5 8.2 2.1 1.7 1 0 0 1 1 1 0 Urotensin II PHD PF00628.24 CEP11028.1 - 2.8e-11 42.9 8.4 6.9e-11 41.6 5.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 CEP11028.1 - 1e-05 25.1 9.6 7e-05 22.4 1.8 3.1 3 0 0 3 3 3 2 CpG binding protein zinc finger C terminal domain APC8 PF04049.8 CEP11028.1 - 0.011 15.5 0.3 0.083 12.6 0.0 2.3 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 zf-RING_2 PF13639.1 CEP11028.1 - 0.73 9.7 6.2 2.1 8.2 4.3 1.8 1 1 0 1 1 1 0 Ring finger domain PHD_2 PF13831.1 CEP11028.1 - 1.8 7.9 8.2 0.1 11.9 1.7 2.0 2 0 0 2 2 2 0 PHD-finger Ribosomal_60s PF00428.14 CEP11029.1 - 6.7e-24 84.1 6.1 8.1e-24 83.8 4.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein CRAL_TRIO PF00650.15 CEP11030.1 - 1.5e-34 118.8 0.0 2.6e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP11030.1 - 4.1e-05 23.6 1.4 5.9e-05 23.1 0.3 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEP11030.1 - 0.0018 18.1 0.0 0.0048 16.8 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF1664 PF07889.7 CEP11033.1 - 0.11 12.2 0.3 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.12 CEP11035.1 - 1.4e-05 25.1 0.3 2.3e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 CEP11035.1 - 0.0048 16.6 0.1 0.0078 16.0 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AF0941-like PF14591.1 CEP11035.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 AF0941-like DUF3829 PF12889.2 CEP11035.1 - 0.053 12.7 0.4 0.058 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) UBN2_2 PF14227.1 CEP11035.1 - 0.094 12.2 0.3 0.14 11.7 0.2 1.4 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF713 PF05218.9 CEP11035.1 - 0.1 12.3 1.9 0.12 12.1 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF713) Transposase_21 PF02992.9 CEP11036.1 - 0.032 13.3 0.1 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 Transposase family tnp2 zf-CCHC PF00098.18 CEP11038.1 - 1.5e-06 27.8 13.1 0.00095 18.9 1.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP11038.1 - 0.0017 17.9 8.0 0.16 11.6 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP11038.1 - 0.023 14.2 5.6 0.023 14.2 3.9 2.5 1 1 1 2 2 2 0 Zinc knuckle MCLC PF05934.6 CEP11039.1 - 0.07 11.4 0.1 0.074 11.3 0.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Rota_Capsid_VP6 PF00980.12 CEP11039.1 - 0.12 11.0 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 Sp100 PF03172.8 CEP11040.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 1 1 2 2 2 0 Sp100 domain Exo_endo_phos PF03372.18 CEP11041.1 - 3.1e-08 33.8 1.9 6.2e-08 32.8 1.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CEP11041.1 - 2.3e-07 31.0 0.1 6.2e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Mhr1 PF12829.2 CEP11041.1 - 0.014 15.1 0.4 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination RVT_1 PF00078.22 CEP11044.1 - 7.9e-24 84.2 0.1 1e-23 83.8 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Snf7 PF03357.16 CEP11046.1 - 3.1e-44 150.3 25.0 3.1e-44 150.3 17.3 1.4 2 0 0 2 2 2 1 Snf7 Glyco_hydro_17 PF00332.13 CEP11046.1 - 0.022 13.8 0.2 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Thioredoxin_7 PF13899.1 CEP11046.1 - 0.05 13.6 0.3 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Thioredoxin-like HECT PF00632.20 CEP11047.1 - 7.9e-91 304.4 1.0 2.6e-90 302.7 0.2 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 CEP11047.1 - 0.04 13.5 0.5 0.04 13.5 0.3 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif E1-E2_ATPase PF00122.15 CEP11048.1 - 7.6e-26 90.5 0.0 1.9e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEP11048.1 - 6e-17 62.7 0.0 1.6e-16 61.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP11048.1 - 4.4e-10 40.0 2.8 1e-09 38.8 1.9 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP11048.1 - 1.6e-05 24.7 0.0 9e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEP11048.1 - 0.00038 20.1 0.2 0.0017 17.9 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CwfJ_C_1 PF04677.10 CEP11049.1 - 4.4e-33 113.5 0.0 7.9e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CEP11049.1 - 2.3e-26 92.1 0.6 1.2e-25 89.8 0.2 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 zf-C3HC4_2 PF13923.1 CEP11050.1 - 2e-09 37.2 23.1 4.3e-05 23.4 6.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP11050.1 - 1.8e-08 34.0 19.5 1.8e-07 30.8 5.2 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 CEP11050.1 - 1.5e-07 30.9 22.1 3.6e-05 23.3 6.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CEP11050.1 - 1.1e-06 28.0 4.7 1.1e-06 28.0 3.3 2.9 2 1 1 3 3 2 1 Rtf2 RING-finger zf-RING_5 PF14634.1 CEP11050.1 - 1.3e-06 28.0 9.3 1.3e-06 28.0 6.4 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEP11050.1 - 0.0015 18.3 20.2 0.0094 15.8 5.3 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CEP11050.1 - 0.0016 18.0 23.6 0.0029 17.2 6.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP11050.1 - 0.0038 16.8 7.3 0.0038 16.8 5.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 CEP11050.1 - 0.016 15.2 3.4 0.016 15.2 2.4 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CEP11050.1 - 0.04 13.7 8.9 0.59 9.9 1.6 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Asp-B-Hydro_N PF05279.6 CEP11050.1 - 0.34 10.7 10.1 0.46 10.2 7.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PLRV_ORF5 PF01690.12 CEP11050.1 - 0.5 9.4 7.3 0.66 9.0 5.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FYVE PF01363.16 CEP11050.1 - 2.1 8.3 19.8 0.24 11.3 5.6 2.9 2 2 0 2 2 2 0 FYVE zinc finger zf-C2H2 PF00096.21 CEP11051.1 - 1.2e-13 50.5 28.0 2.7e-05 24.2 2.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP11051.1 - 2e-13 49.8 26.8 1.9e-07 30.9 0.8 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP11051.1 - 1.3e-05 25.1 33.1 0.005 17.0 2.8 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger HALZ PF02183.13 CEP11051.1 - 6.8e-05 22.5 4.6 0.011 15.3 1.3 2.7 2 0 0 2 2 2 2 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 CEP11051.1 - 0.0089 15.7 8.4 0.0089 15.7 5.8 2.3 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF1640 PF07798.6 CEP11051.1 - 0.15 12.1 0.2 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) zf-C2H2_6 PF13912.1 CEP11051.1 - 0.21 11.5 18.2 1 9.3 0.0 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger IncA PF04156.9 CEP11051.1 - 0.31 10.6 18.3 0.24 10.9 1.0 2.3 2 0 0 2 2 2 0 IncA protein E_Pc_C PF06752.7 CEP11051.1 - 0.41 10.1 40.2 0.019 14.4 19.2 2.6 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus OmpH PF03938.9 CEP11051.1 - 1.6 8.6 22.3 3.7 7.4 9.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 CEP11051.1 - 1.9 8.7 7.3 5.5 7.2 1.4 2.2 2 0 0 2 2 2 0 AAA domain Zn-ribbon_8 PF09723.5 CEP11051.1 - 3.5 7.6 10.1 12 5.9 0.2 3.5 2 1 2 4 4 4 0 Zinc ribbon domain DUF4407 PF14362.1 CEP11051.1 - 4.8 6.0 12.4 6 5.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FHIPEP PF00771.15 CEP11051.1 - 9.5 4.4 12.6 3 6.0 3.7 2.0 2 0 0 2 2 2 0 FHIPEP family KilA-N PF04383.8 CEP11052.1 - 0.00031 20.3 0.0 0.0024 17.4 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain DLIC PF05783.6 CEP11053.1 - 1.7e-63 214.9 18.2 7.6e-54 183.1 4.4 4.9 2 1 1 3 3 3 3 Dynein light intermediate chain (DLIC) Miro PF08477.8 CEP11053.1 - 0.00041 20.8 0.1 0.0057 17.1 0.0 2.7 3 1 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 CEP11053.1 - 0.0044 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CEP11053.1 - 0.013 15.0 0.2 0.029 13.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CEP11053.1 - 0.015 15.4 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEP11053.1 - 0.022 15.0 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 CEP11053.1 - 0.032 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CEP11053.1 - 0.05 13.0 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 CEP11053.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.10 CEP11053.1 - 0.18 10.4 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF3720 PF12517.3 CEP11053.1 - 0.44 11.2 9.5 1.3 9.7 4.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) 2-Hacid_dh_C PF02826.14 CEP11054.1 - 5.1e-55 185.3 0.0 7.1e-55 184.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEP11054.1 - 2.1e-20 72.5 0.0 2.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.15 CEP11054.1 - 0.085 12.9 0.1 0.28 11.2 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cyclin_N PF00134.18 CEP11055.1 - 6.3e-13 48.4 0.8 3.7e-11 42.6 0.1 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CEP11055.1 - 5.1e-07 29.6 0.1 1.2e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.14 CEP11055.1 - 0.0042 16.8 0.4 2.9 7.7 0.1 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat DUF2497 PF10691.4 CEP11055.1 - 0.079 12.9 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) IDO PF01231.13 CEP11056.1 - 1.1e-134 449.0 0.0 4.8e-126 420.6 0.0 2.1 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase HSP70 PF00012.15 CEP11059.1 - 3.5e-05 21.9 0.2 4.7e-05 21.5 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MDM31_MDM32 PF08118.6 CEP11060.1 - 0.017 13.6 0.1 0.022 13.2 0.1 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Cytochrom_C1 PF02167.10 CEP11060.1 - 0.06 12.9 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C1 family GCR1_C PF12550.3 CEP11061.1 - 1.7e-15 56.6 0.7 2.8e-15 55.9 0.5 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes 3-dmu-9_3-mt PF06983.8 CEP11061.1 - 0.033 14.5 0.0 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase Aminotran_4 PF01063.14 CEP11063.1 - 5.2e-16 58.8 0.0 8.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV DUF221 PF02714.10 CEP11064.1 - 8.1e-79 264.8 28.6 1.4e-78 264.0 19.8 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEP11064.1 - 2.1e-23 82.6 2.8 5.1e-21 74.8 0.3 3.7 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CEP11064.1 - 5e-14 52.5 0.0 1.5e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3343 PF11823.3 CEP11064.1 - 0.12 11.6 0.0 0.32 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Sld5 PF05916.6 CEP11065.1 - 2.7e-06 27.6 1.4 5.2e-06 26.6 1.0 1.5 1 0 0 1 1 1 1 GINS complex protein GTSE1_N PF15259.1 CEP11066.1 - 0.15 11.9 4.2 0.2 11.6 2.9 1.1 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Pex14_N PF04695.8 CEP11066.1 - 3.4 7.7 6.4 3.4 7.7 4.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 CEP11067.1 - 1e-54 185.4 0.0 1.7e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11067.1 - 2.8e-36 124.9 0.0 4.2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP11067.1 - 1.3e-07 30.8 0.0 2.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like NusB PF01029.13 CEP11067.1 - 0.039 13.9 0.0 0.95 9.4 0.0 2.7 3 0 0 3 3 3 0 NusB family Seadorna_VP7 PF07387.6 CEP11067.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BAR PF03114.13 CEP11068.1 - 2.5e-32 112.2 7.1 4.2e-32 111.4 4.9 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CEP11068.1 - 2.5e-16 58.7 0.1 4.6e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP11068.1 - 1.9e-14 52.9 0.1 3.3e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP11068.1 - 2.5e-11 42.8 0.0 4.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2361 PF10153.4 CEP11068.1 - 0.078 13.1 1.2 0.24 11.6 0.8 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Vps5 PF09325.5 CEP11068.1 - 0.24 10.6 5.2 0.45 9.7 3.6 1.4 1 0 0 1 1 1 0 Vps5 C terminal like AAA PF00004.24 CEP11069.1 - 7.5e-13 48.8 0.2 3e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEP11069.1 - 0.087 13.6 0.0 0.16 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CEP11069.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gar1 PF04410.9 CEP11070.1 - 8.9e-39 132.4 2.6 8.9e-39 132.4 1.8 2.3 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region Epimerase PF01370.16 CEP11071.1 - 3.3e-69 232.9 0.0 6.3e-69 232.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CEP11071.1 - 2.4e-09 36.5 0.0 4.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 CEP11071.1 - 0.00036 19.8 0.0 0.00071 18.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 CEP11071.1 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PAS_11 PF14598.1 CEP11071.1 - 0.015 15.2 0.0 0.059 13.3 0.0 2.0 2 0 0 2 2 2 0 PAS domain NAD_binding_10 PF13460.1 CEP11071.1 - 0.023 14.7 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 CEP11071.1 - 0.054 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase_Csub PF13950.1 CEP11071.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Abhydrolase_6 PF12697.2 CEP11072.1 - 6.6e-23 81.7 0.0 8.9e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP11072.1 - 1.6e-14 54.0 0.2 7.9e-14 51.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP11072.1 - 1.9e-13 50.3 0.0 2.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEP11072.1 - 2.2e-05 24.1 0.2 3.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 CEP11072.1 - 4.6e-05 23.7 0.0 7.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 CEP11072.1 - 7.8e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 CEP11072.1 - 0.00025 20.0 0.1 0.00033 19.6 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF676 PF05057.9 CEP11072.1 - 0.00031 20.1 0.6 0.00048 19.4 0.4 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2305 PF10230.4 CEP11072.1 - 0.00072 19.0 0.2 0.0011 18.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Methyltransf_32 PF13679.1 CEP11072.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Lipase_3 PF01764.20 CEP11072.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 CEP11072.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.8 CEP11072.1 - 0.022 14.3 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Cutinase PF01083.17 CEP11072.1 - 0.031 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF900 PF05990.7 CEP11072.1 - 0.044 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAF-AH_p_II PF03403.8 CEP11072.1 - 0.064 11.5 0.7 0.075 11.3 0.3 1.5 1 1 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF1057 PF06342.7 CEP11072.1 - 0.065 12.0 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2974 PF11187.3 CEP11072.1 - 0.065 12.5 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.13 CEP11072.1 - 0.11 11.6 0.0 2.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Syntaxin PF00804.20 CEP11073.1 - 0.014 15.5 0.2 0.016 15.3 0.2 1.2 1 0 0 1 1 1 0 Syntaxin Mito_carr PF00153.22 CEP11074.1 - 1.9e-71 235.8 3.3 1.1e-23 82.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 CEP11075.1 - 5.4e-43 144.8 3.9 8.6e-43 144.1 2.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1989 PF09347.5 CEP11075.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) Acyltransferase PF01553.16 CEP11076.1 - 1.2e-13 50.5 0.1 2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NIF PF03031.13 CEP11077.1 - 2.3e-25 89.1 0.0 5e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 CEP11077.1 - 3.9e-12 45.8 0.0 1e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CEP11077.1 - 1.6e-06 28.2 0.0 6.2e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AA_permease PF00324.16 CEP11078.1 - 2.4e-125 418.5 59.2 2.9e-125 418.3 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEP11078.1 - 4.2e-38 131.0 62.5 6.1e-38 130.4 43.3 1.2 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 CEP11079.1 - 2.8e-55 187.2 0.0 4.5e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11079.1 - 2e-25 89.3 0.0 3.6e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CEP11079.1 - 1e-19 70.2 1.8 9.4e-11 41.5 0.0 3.0 3 0 0 3 3 3 2 POLO box duplicated region Ank_2 PF12796.2 CEP11080.1 - 4.7e-53 177.4 11.4 7.7e-16 58.2 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Abhydrolase_3 PF07859.8 CEP11080.1 - 8.2e-46 156.2 0.0 1.5e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ank PF00023.25 CEP11080.1 - 1.6e-35 119.1 0.0 1.9e-05 24.2 0.0 8.0 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 CEP11080.1 - 2.9e-34 116.3 2.9 7e-08 32.4 0.0 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP11080.1 - 3.6e-34 116.5 4.1 4.8e-10 39.6 0.0 6.8 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP11080.1 - 4e-26 88.4 8.0 0.00027 20.8 0.0 9.4 9 1 0 9 9 9 6 Ankyrin repeat DUF2424 PF10340.4 CEP11080.1 - 2.9e-15 55.7 0.1 5.7e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CEP11080.1 - 2.6e-05 23.9 0.0 5.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP11080.1 - 0.024 13.8 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.23 CEP11080.1 - 0.037 12.7 0.0 0.18 10.4 0.0 2.0 3 0 0 3 3 3 0 Carboxylesterase family zf-DBF PF07535.7 CEP11081.1 - 9.3e-13 47.6 3.1 2.3e-12 46.3 2.2 1.7 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.5 CEP11081.1 - 1.4e-12 47.4 0.0 1.4e-12 47.4 0.0 2.6 3 0 0 3 3 3 1 Dfp1/Him1, central region PTCB-BRCT PF12738.2 CEP11081.1 - 0.00039 20.2 0.0 0.0009 19.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CEP11081.1 - 0.0022 18.1 0.4 0.0052 16.8 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF1284 PF06935.6 CEP11081.1 - 0.0085 16.2 0.3 0.021 14.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1284) NIF PF03031.13 CEP11082.1 - 6e-27 94.2 0.8 1.3e-26 93.2 0.5 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acyl-CoA_dh_1 PF00441.19 CEP11083.1 - 7.5e-33 113.7 0.3 1.1e-32 113.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEP11083.1 - 4e-20 71.0 0.1 1.6e-19 69.1 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 CEP11083.1 - 1.1e-18 66.7 0.0 2.5e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 CEP11083.1 - 3.7e-11 43.6 0.0 7.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEP11083.1 - 1.5e-06 28.4 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mso1_Sec1_bdg PF14475.1 CEP11084.1 - 6.4e-05 22.2 0.1 0.00017 20.9 0.1 1.8 1 0 0 1 1 1 1 Sec1-binding region of Mso1 zf-C2H2_4 PF13894.1 CEP11085.1 - 0.033 14.5 0.3 0.079 13.3 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CEP11085.1 - 0.04 14.0 1.9 0.04 14.0 1.3 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Jacalin PF01419.12 CEP11086.1 - 0.0096 15.8 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain HNH PF01844.18 CEP11086.1 - 0.14 12.0 0.0 0.14 12.0 0.0 2.9 3 0 0 3 3 3 0 HNH endonuclease NMD3 PF04981.8 CEP11087.1 - 0.041 12.9 1.1 0.073 12.1 0.0 1.9 2 0 0 2 2 2 0 NMD3 family DUF1272 PF06906.6 CEP11087.1 - 0.08 12.7 5.2 0.16 11.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.2 CEP11087.1 - 3.1 7.7 8.3 2.1 8.2 1.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF164 PF02591.10 CEP11087.1 - 3.1 7.6 6.1 2.1 8.2 1.6 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain peroxidase PF00141.18 CEP11088.1 - 4.1e-45 154.0 0.0 6e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF3612 PF12268.3 CEP11089.1 - 0.38 10.5 2.7 8.4 6.1 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3612) TTL PF03133.10 CEP11090.1 - 1.3e-56 191.7 3.6 3.9e-56 190.1 2.5 1.7 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family EFhand_Ca_insen PF08726.5 CEP11090.1 - 1.7 8.6 8.0 27 4.8 0.1 3.8 3 0 0 3 3 3 0 Ca2+ insensitive EF hand TPR_11 PF13414.1 CEP11091.1 - 2.2e-09 36.8 10.1 0.00025 20.6 0.6 3.0 2 1 1 3 3 3 2 TPR repeat FAR1 PF03101.10 CEP11091.1 - 7.4e-08 32.8 0.8 2.2e-07 31.2 0.6 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain SHNi-TPR PF10516.4 CEP11091.1 - 2.4e-07 29.8 4.1 5.2e-06 25.6 0.0 3.6 3 1 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 CEP11091.1 - 2.9e-07 30.3 6.6 4e-06 26.6 0.7 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11091.1 - 2.3e-05 23.8 1.5 2.1 8.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat DBD_Tnp_Mut PF03108.10 CEP11091.1 - 0.00024 20.5 0.1 0.00024 20.5 0.1 2.5 2 0 0 2 2 2 1 MuDR family transposase TPR_16 PF13432.1 CEP11091.1 - 0.0026 18.3 6.8 0.25 12.0 0.5 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP11091.1 - 0.0038 16.7 6.5 0.028 14.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP11091.1 - 0.044 13.7 9.8 1.6 8.8 0.1 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 CEP11091.1 - 0.061 13.5 1.8 7.2 7.0 0.2 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Flavokinase PF01687.12 CEP11092.1 - 1.8e-42 144.1 0.0 2.1e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Glyco_hydro_31 PF01055.21 CEP11093.1 - 4.9e-69 233.2 2.0 8.7e-69 232.4 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CEP11093.1 - 4.5e-05 23.2 0.3 0.00035 20.3 0.2 2.4 1 1 0 1 1 1 1 Galactose mutarotase-like PapC_N PF13954.1 CEP11093.1 - 0.043 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 PapC N-terminal domain Grp1_Fun34_YaaH PF01184.14 CEP11094.1 - 2.2e-26 92.4 23.7 2.6e-26 92.2 16.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family rve PF00665.21 CEP11095.1 - 0.00024 21.2 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Herpes_capsid PF06112.6 CEP11097.1 - 0.19 11.7 0.4 0.31 11.0 0.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Anemone_cytotox PF06369.7 CEP11098.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein Sif PF06767.6 CEP11099.1 - 7e-06 25.0 0.4 9e-06 24.6 0.3 1.1 1 0 0 1 1 1 1 Sif protein SMC_Nse1 PF07574.8 CEP11099.1 - 0.02 14.5 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Pkinase PF00069.20 CEP11100.1 - 4.5e-48 163.6 0.0 5.6e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11100.1 - 2.7e-26 92.1 0.0 3.3e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP11100.1 - 2.6e-08 33.1 0.0 1.3e-05 24.3 0.0 2.1 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 CEP11100.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP11100.1 - 0.045 13.3 0.1 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-RVT PF13966.1 CEP11101.1 - 0.0054 17.0 1.3 0.013 15.7 0.9 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Opi1 PF08618.5 CEP11102.1 - 1.2e-43 149.6 9.3 3.8e-41 141.4 6.5 2.1 1 1 0 1 1 1 1 Transcription factor Opi1 Defensin_big PF14862.1 CEP11102.1 - 0.075 13.1 0.6 0.16 12.0 0.2 1.7 1 1 1 2 2 2 0 Big defensin DSPc PF00782.15 CEP11103.1 - 4.6e-07 29.4 0.0 1.4e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP11103.1 - 4e-05 23.0 0.0 0.00018 20.9 0.0 1.9 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Sgf11 PF08209.6 CEP11103.1 - 0.00035 19.8 0.1 0.00035 19.8 0.0 2.1 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) CDKN3 PF05706.7 CEP11103.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pkinase PF00069.20 CEP11104.1 - 3.1e-33 115.0 0.0 1.2e-17 63.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11104.1 - 6.8e-11 41.7 0.0 2.6e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pneumovirus_M2 PF06436.6 CEP11104.1 - 0.029 13.5 0.8 0.052 12.7 0.5 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) ABC1 PF03109.11 CEP11104.1 - 0.11 12.4 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC1 family zf-RING_2 PF13639.1 CEP11106.1 - 1.2e-12 47.4 6.0 2e-12 46.7 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CEP11106.1 - 5.4e-09 35.5 5.8 9.6e-09 34.7 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP11106.1 - 9.4e-09 35.1 7.8 1.6e-08 34.3 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP11106.1 - 1.6e-08 34.0 4.1 2.7e-08 33.3 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CEP11106.1 - 1.3e-06 28.4 2.5 3e-06 27.2 1.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEP11106.1 - 6.9e-06 25.6 7.4 1.2e-05 24.8 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP11106.1 - 0.0046 16.6 2.9 0.018 14.7 2.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 CEP11106.1 - 0.0046 16.5 5.9 0.008 15.7 4.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PA PF02225.17 CEP11106.1 - 0.0084 15.7 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_4 PF15227.1 CEP11106.1 - 0.012 15.4 6.1 0.03 14.2 4.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2073 PF09846.4 CEP11106.1 - 0.022 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) DER1 PF04511.10 CEP11107.1 - 0.02 14.3 1.4 0.023 14.2 0.9 1.0 1 0 0 1 1 1 0 Der1-like family DUF1298 PF06974.8 CEP11107.1 - 0.13 12.0 4.2 0.16 11.7 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Herpes_US9 PF06072.6 CEP11107.1 - 3.7 7.4 4.9 2.4 8.0 0.4 2.3 1 1 1 2 2 2 0 Alphaherpesvirus tegument protein US9 G_glu_transpept PF01019.16 CEP11108.1 - 6.6e-148 493.3 0.0 6.6e-148 493.3 0.0 1.8 3 0 0 3 3 3 1 Gamma-glutamyltranspeptidase TAF4 PF05236.9 CEP11108.1 - 7.4e-17 61.4 13.0 2.1e-14 53.4 8.9 2.5 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Vac_ImportDeg PF09783.4 CEP11109.1 - 4.4e-61 205.4 1.6 6e-61 204.9 1.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein SecY PF00344.15 CEP11110.1 - 3.3e-75 253.1 16.5 4.5e-75 252.7 11.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CEP11110.1 - 6.6e-15 54.3 1.3 1.9e-14 52.8 0.1 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p Nop14 PF04147.7 CEP11110.1 - 0.0021 16.0 7.4 0.0028 15.6 5.1 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CEP11110.1 - 0.04 11.9 6.0 0.054 11.5 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CEP11110.1 - 0.063 11.7 6.9 0.084 11.3 4.8 1.1 1 0 0 1 1 1 0 Daxx Family Tom22 PF04281.8 CEP11110.1 - 0.14 11.6 8.7 0.24 10.9 5.5 1.7 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TFIIA PF03153.8 CEP11110.1 - 0.3 10.9 14.2 0.43 10.4 9.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 CEP11110.1 - 1.6 8.4 13.0 2.4 7.8 9.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.4 CEP11110.1 - 9.9 4.7 21.2 15 4.2 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PUL PF08324.6 CEP11111.1 - 0.059 12.1 1.1 0.098 11.4 0.7 1.3 1 0 0 1 1 1 0 PUL domain Sulfate_transp PF00916.15 CEP11112.1 - 3.7e-75 252.5 7.9 8.1e-75 251.4 5.5 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP11112.1 - 6.4e-33 112.2 3.3 6.4e-33 112.2 2.3 3.9 4 1 1 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEP11112.1 - 1.3e-11 43.9 0.0 2.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CEP11112.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain CBM_21 PF03370.8 CEP11113.1 - 6.1e-25 87.3 2.1 1.1e-24 86.6 1.5 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CEP11113.1 - 0.04 14.0 0.3 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Nucleoplasmin PF03066.10 CEP11113.1 - 0.92 9.0 5.3 2.5 7.5 2.3 2.2 2 0 0 2 2 2 0 Nucleoplasmin Sec63 PF02889.11 CEP11114.1 - 1.6e-40 139.3 0.4 2.6e-40 138.5 0.3 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CEP11114.1 - 1.4e-22 79.9 0.2 5.5e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CEP11114.1 - 4.2e-09 36.4 0.1 1.4e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEP11114.1 - 1.9e-08 34.0 0.0 4.3e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CEP11114.1 - 0.0043 17.2 0.1 0.042 13.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP11114.1 - 0.016 14.9 0.0 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 CEP11114.1 - 0.027 13.9 0.0 0.072 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 CEP11114.1 - 0.035 13.0 0.0 0.076 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1900 PF08954.6 CEP11115.1 - 7.7e-38 129.0 0.0 2.2e-37 127.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) WD40 PF00400.27 CEP11115.1 - 5.9e-14 51.3 3.6 5.8e-05 22.8 0.0 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF1899 PF08953.6 CEP11115.1 - 0.00035 20.1 0.0 0.00076 19.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Nucleoporin_N PF08801.6 CEP11115.1 - 0.0036 16.0 0.0 0.0052 15.5 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like eIF2A PF08662.6 CEP11115.1 - 0.004 16.8 0.1 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A F-box-like PF12937.2 CEP11116.1 - 5.6e-06 25.9 0.0 6.5e-05 22.5 0.0 2.4 1 1 1 2 2 2 1 F-box-like IpaB_EvcA PF03278.8 CEP11116.1 - 0.072 12.3 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 IpaB/EvcA family F-box-like PF12937.2 CEP11117.1 - 0.00028 20.5 0.0 0.00053 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like Acetyltransf_1 PF00583.19 CEP11118.1 - 8.6e-14 51.3 0.1 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP11118.1 - 1.1e-10 41.5 0.2 1.7e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP11118.1 - 0.0048 16.7 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydro_lipase PF04083.11 CEP11119.1 - 3.4e-19 67.9 0.0 1e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CEP11119.1 - 8.9e-07 29.0 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP11119.1 - 0.0019 17.8 0.0 0.0073 15.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 CEP11119.1 - 0.0058 15.8 0.1 0.66 9.1 0.0 3.0 3 0 0 3 3 3 1 Secretory lipase Exo_endo_phos PF03372.18 CEP11120.1 - 8.5e-09 35.7 0.1 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 CEP11121.1 - 6.9e-06 25.7 13.1 0.002 17.9 1.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP11121.1 - 0.0086 15.7 8.0 0.38 10.4 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP11121.1 - 0.35 10.3 13.8 0.045 13.2 3.7 2.5 1 1 1 2 2 2 0 Zinc knuckle Sugar_tr PF00083.19 CEP11122.1 - 6e-77 259.1 28.0 7.1e-77 258.8 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP11122.1 - 5.2e-16 58.3 35.2 1.5e-15 56.7 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 4HBT PF03061.17 CEP11123.1 - 2.8e-15 56.1 3.0 8.2e-08 32.2 0.0 3.3 2 1 1 3 3 3 3 Thioesterase superfamily Tubulin PF00091.20 CEP11124.1 - 7.6e-61 205.6 0.0 1.2e-60 204.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEP11124.1 - 2.2e-45 153.7 0.5 5.1e-45 152.5 0.0 1.9 2 0 0 2 2 2 1 Tubulin C-terminal domain THF_DHG_CYH PF00763.18 CEP11124.1 - 4.2e-18 65.4 0.1 1e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CEP11124.1 - 1.8e-12 46.6 0.2 1.4e-10 40.4 0.1 2.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain bZIP_2 PF07716.10 CEP11125.1 - 1.7e-12 46.9 8.5 3e-12 46.1 5.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP11125.1 - 1.8e-05 24.5 6.9 4.2e-05 23.4 4.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor CENP-F_leu_zip PF10473.4 CEP11125.1 - 0.025 14.4 2.2 0.025 14.4 1.6 2.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 CEP11125.1 - 0.036 13.5 1.6 0.1 12.1 1.1 1.8 1 0 0 1 1 1 0 Septum formation initiator WXG100 PF06013.7 CEP11125.1 - 0.038 13.9 0.3 0.097 12.6 0.2 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG PspB PF06667.7 CEP11125.1 - 0.054 13.4 1.0 0.11 12.4 0.7 1.5 1 0 0 1 1 1 0 Phage shock protein B CLTH PF10607.4 CEP11125.1 - 0.058 13.0 0.4 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Terminase_2 PF03592.11 CEP11125.1 - 0.066 13.4 3.6 0.11 12.7 2.5 1.3 1 0 0 1 1 1 0 Terminase small subunit EMP24_GP25L PF01105.19 CEP11125.1 - 0.72 9.5 4.1 0.25 11.0 1.0 1.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.5 CEP11125.1 - 4.4 7.4 6.7 2.3 8.3 3.2 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0014 PF03649.8 CEP11126.1 - 6.1e-32 110.7 7.1 9.7e-32 110.0 4.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) RINGv PF12906.2 CEP11126.1 - 7.3e-09 35.5 6.1 1.6e-08 34.4 4.2 1.5 1 0 0 1 1 1 1 RING-variant domain BPD_transp_1 PF00528.17 CEP11126.1 - 0.00057 19.4 8.0 0.00057 19.4 5.6 1.9 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component Arif-1 PF06770.6 CEP11126.1 - 0.1 11.9 5.2 0.16 11.3 0.3 2.6 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) PGG PF13962.1 CEP11126.1 - 0.12 12.0 0.2 0.12 12.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function zf-AD PF07776.10 CEP11126.1 - 0.17 11.9 3.1 0.51 10.3 2.2 1.8 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-C3HC4_3 PF13920.1 CEP11126.1 - 0.33 10.6 6.2 0.96 9.1 4.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP11126.1 - 0.6 9.9 8.3 1.3 8.8 5.7 1.6 1 0 0 1 1 1 0 Ring finger domain FtsX PF02687.16 CEP11126.1 - 1.3 8.7 22.6 0.074 12.8 7.2 3.4 3 1 1 4 4 4 0 FtsX-like permease family zf-RING_4 PF14570.1 CEP11126.1 - 2 8.0 9.5 10 5.7 6.6 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 CEP11128.1 - 1.4e-10 40.6 14.5 2.8e-10 39.7 10.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEP11128.1 - 0.0023 17.1 9.4 0.0041 16.3 6.5 1.4 1 0 0 1 1 1 1 PHD-finger Pneumovirus_M2 PF06436.6 CEP11128.1 - 0.03 13.5 0.0 0.077 12.2 0.0 1.6 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) zf-CW PF07496.10 CEP11128.1 - 0.063 12.9 5.3 0.21 11.3 3.6 1.9 1 0 0 1 1 1 0 CW-type Zinc Finger PCI PF01399.22 CEP11129.1 - 1.9e-10 40.9 0.2 5.8e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 PCI domain AP-5_subunit_s1 PF15001.1 CEP11129.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 HTH_40 PF14493.1 CEP11129.1 - 0.038 14.1 0.9 0.12 12.6 0.1 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain Sigma70_ECF PF07638.6 CEP11129.1 - 0.054 13.1 0.7 2.4 7.7 0.0 2.9 2 1 1 3 3 3 0 ECF sigma factor ING PF12998.2 CEP11130.1 - 2.9e-12 46.7 6.9 2.9e-12 46.7 4.8 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CEP11130.1 - 2.8e-10 39.7 8.4 5.9e-10 38.6 5.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEP11130.1 - 0.0075 15.5 3.1 0.017 14.4 2.1 1.6 1 0 0 1 1 1 1 PHD-finger CDC45 PF02724.9 CEP11130.1 - 0.043 11.8 4.8 0.082 10.9 3.3 1.4 1 0 0 1 1 1 0 CDC45-like protein MCD PF05292.6 CEP11130.1 - 0.088 11.4 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) TRAP_alpha PF03896.11 CEP11130.1 - 0.13 11.2 8.2 0.12 11.3 4.6 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Merozoite_SPAM PF07133.6 CEP11130.1 - 0.62 9.9 22.0 1.4 8.7 15.3 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Abhydrolase_6 PF12697.2 CEP11131.1 - 2.7e-33 115.7 0.0 3.4e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP11131.1 - 1.7e-20 73.5 0.1 4.7e-19 68.8 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP11131.1 - 5.2e-19 68.4 0.0 8.4e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CEP11131.1 - 2e-08 34.0 0.0 2.3e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.3 CEP11131.1 - 6e-08 32.4 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 CEP11131.1 - 7.6e-05 22.0 0.1 0.17 11.1 0.0 2.7 2 1 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.15 CEP11131.1 - 0.0005 20.3 0.0 0.0011 19.1 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S9 PF00326.16 CEP11131.1 - 0.03 13.5 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.6 CEP11131.1 - 0.064 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 CEP11131.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Mating_N PF12731.2 CEP11131.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 FHA PF00498.21 CEP11132.1 - 2.6e-17 62.6 0.0 5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain DOR PF14839.1 CEP11132.1 - 0.014 15.1 1.4 0.08 12.6 0.0 2.5 2 0 0 2 2 2 0 DOR family DUF1961 PF09224.6 CEP11133.1 - 0.049 12.7 0.1 0.078 12.0 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1961) PSP1 PF04468.7 CEP11134.1 - 1.6e-07 31.1 0.3 1.6e-07 31.1 0.2 2.4 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Med15 PF09606.5 CEP11134.1 - 0.0093 14.2 24.0 0.013 13.7 16.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CEP11134.1 - 0.19 10.4 33.3 0.41 9.3 23.1 1.6 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TSA PF03249.8 CEP11134.1 - 0.28 9.6 12.8 0.46 8.9 8.8 1.3 1 0 0 1 1 1 0 Type specific antigen Zip PF02535.17 CEP11134.1 - 7.4 5.4 6.9 11 4.8 4.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM51 PF15345.1 CEP11134.1 - 9.1 5.8 11.7 2.6 7.6 5.7 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 OATP PF03137.15 CEP11134.1 - 9.3 4.1 6.8 15 3.4 4.7 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GATA PF00320.22 CEP11135.1 - 2.8e-17 61.7 3.3 6e-17 60.6 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CEP11135.1 - 2.7e-14 52.4 1.4 5.3e-14 51.4 1.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Arrestin_C PF02752.17 CEP11136.1 - 3.5e-20 72.5 0.0 3.4e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP11136.1 - 5.3e-12 45.7 0.0 1.9e-11 43.9 0.0 1.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CEP11136.1 - 0.00064 19.2 0.3 0.0035 16.8 0.1 2.2 2 1 0 2 2 2 1 Arrestin_N terminal like Vps26 PF03643.10 CEP11136.1 - 0.0035 16.1 0.0 0.0062 15.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 SUV3_C PF12513.3 CEP11137.1 - 7.2e-13 47.7 2.2 1.1e-12 47.2 0.2 2.4 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CEP11137.1 - 5e-10 39.1 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IGR PF09597.5 CEP11137.1 - 0.065 13.1 0.5 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 IGR protein motif HSBP1 PF06825.7 CEP11138.1 - 2.8e-09 36.4 0.1 3.7e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 CEP11138.1 - 5.6e-05 22.4 1.7 0.00036 19.8 1.2 2.1 1 1 1 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin Prefoldin_2 PF01920.15 CEP11138.1 - 0.0078 15.9 0.2 0.0089 15.7 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Fzo_mitofusin PF04799.8 CEP11138.1 - 0.009 15.4 0.3 0.0094 15.3 0.2 1.1 1 0 0 1 1 1 1 fzo-like conserved region NPV_P10 PF05531.7 CEP11138.1 - 0.015 15.5 0.5 0.035 14.3 0.2 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PspB PF06667.7 CEP11138.1 - 0.017 15.0 0.8 0.16 11.9 0.3 2.0 1 1 1 2 2 2 0 Phage shock protein B Baculo_PEP_C PF04513.7 CEP11138.1 - 0.021 14.6 1.5 0.025 14.4 1.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tektin PF03148.9 CEP11138.1 - 0.036 12.6 0.2 0.036 12.6 0.1 1.0 1 0 0 1 1 1 0 Tektin family Apolipoprotein PF01442.13 CEP11138.1 - 0.047 13.2 0.1 0.051 13.0 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Synaptobrevin PF00957.16 CEP11138.1 - 0.065 12.8 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF1515 PF07439.6 CEP11138.1 - 0.067 13.0 0.1 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Gon7 PF08738.5 CEP11138.1 - 0.11 12.4 0.8 0.13 12.2 0.5 1.1 1 0 0 1 1 1 0 Gon7 family DUF148 PF02520.12 CEP11138.1 - 0.14 11.9 0.2 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 XhlA PF10779.4 CEP11138.1 - 0.18 11.7 0.7 0.31 10.9 0.5 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Peptidase_C65 PF10275.4 CEP11139.1 - 2.8e-63 213.5 0.2 3.3e-63 213.3 0.2 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 CEP11139.1 - 2.4e-08 34.6 0.1 5.4e-07 30.2 0.1 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease DUF281 PF03436.8 CEP11140.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF281) CAP_GLY PF01302.20 CEP11141.1 - 7.5e-22 76.8 0.8 1.2e-21 76.1 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain IncA PF04156.9 CEP11141.1 - 0.0029 17.2 13.4 0.0029 17.2 9.3 5.4 1 1 3 4 4 4 1 IncA protein Reo_sigmaC PF04582.7 CEP11141.1 - 0.0053 15.9 1.5 0.0053 15.9 1.0 3.5 2 1 1 3 3 3 1 Reovirus sigma C capsid protein Atg14 PF10186.4 CEP11141.1 - 0.0056 15.6 18.9 0.0056 15.6 13.1 4.0 1 1 2 4 4 4 1 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 CEP11141.1 - 0.01 15.7 13.7 0.01 15.7 9.5 7.0 2 2 5 7 7 7 0 Afadin- and alpha -actinin-Binding NDK PF00334.14 CEP11142.1 - 1.5e-53 180.1 0.0 2.2e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HSP70 PF00012.15 CEP11143.1 - 6.9e-243 806.9 12.5 7.9e-243 806.7 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP11143.1 - 1.1e-17 63.6 2.3 9.9e-17 60.5 0.9 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CEP11143.1 - 0.00047 19.8 0.0 0.00091 18.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Asp_decarbox PF02261.11 CEP11143.1 - 0.032 13.8 0.0 0.087 12.4 0.0 1.7 1 0 0 1 1 1 0 Aspartate decarboxylase Hydantoinase_A PF01968.13 CEP11143.1 - 0.038 13.1 3.3 0.32 10.0 0.0 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase eIF3_N PF09440.5 CEP11143.1 - 0.092 12.9 5.8 0.042 14.0 2.1 1.8 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Homeobox PF00046.24 CEP11144.1 - 2.3e-16 59.1 1.0 4.8e-16 58.1 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP11144.1 - 0.033 13.8 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.1 CEP11144.1 - 0.05 13.2 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain SH3_2 PF07653.12 CEP11145.1 - 2.2e-06 27.0 0.0 3.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP11145.1 - 5.2e-06 25.7 0.0 9.5e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP11145.1 - 2.8e-05 23.5 0.2 6.4e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Variant SH3 domain DUF2611 PF11022.3 CEP11145.1 - 0.21 11.7 1.1 0.45 10.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) Pyrophosphatase PF00719.14 CEP11146.1 - 5.6e-54 181.8 0.9 8.7e-54 181.1 0.6 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Ribosomal_S6e PF01092.14 CEP11147.1 - 8.5e-63 209.6 0.2 1.6e-62 208.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e BTB_2 PF02214.17 CEP11148.1 - 0.0015 18.7 1.9 0.014 15.5 0.4 2.9 1 1 1 2 2 2 1 BTB/POZ domain Fumble PF03630.9 CEP11148.1 - 0.03 13.1 0.7 0.045 12.5 0.5 1.3 1 0 0 1 1 1 0 Fumble DnaJ PF00226.26 CEP11149.1 - 2e-25 88.2 1.1 4.4e-25 87.1 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 CEP11149.1 - 7.1e-23 80.9 2.6 7.1e-23 80.9 1.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 CEP11149.1 - 0.014 15.2 0.5 0.13 12.2 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3770 PF12603.3 CEP11149.1 - 0.08 12.0 1.1 0.096 11.7 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3770) Fibrillarin PF01269.12 CEP11150.1 - 6.7e-112 371.9 0.0 8.3e-112 371.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CEP11150.1 - 5.5e-05 22.7 0.0 8.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CEP11150.1 - 0.00092 18.8 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEP11150.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rhodanese PF00581.15 CEP11151.1 - 5.3e-28 97.6 0.0 1.3e-12 48.0 0.0 2.4 2 1 1 3 3 3 3 Rhodanese-like domain ALMT PF11744.3 CEP11152.1 - 8.8e-22 77.3 4.0 1.4e-21 76.6 2.8 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC_2 PF13515.1 CEP11152.1 - 2.2e-10 40.5 14.1 3.7e-10 39.7 9.8 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.7 CEP11152.1 - 1.1e-08 34.0 7.5 2.4e-08 32.8 5.2 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF2422 PF10337.4 CEP11152.1 - 0.0022 16.8 10.5 0.025 13.3 0.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2422) Ribosomal_L7Ae PF01248.21 CEP11153.1 - 1.1e-25 88.9 0.0 1.3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CEP11153.1 - 0.0021 17.9 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 CEP11153.1 - 0.017 14.8 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain FlxA PF14282.1 CEP11153.1 - 0.1 12.5 1.8 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 FlxA-like protein Rifin_STEVOR PF02009.11 CEP11154.1 - 1.1 8.8 2.7 1.4 8.4 1.9 1.2 1 0 0 1 1 1 0 Rifin/stevor family MF_alpha_N PF05436.6 CEP11155.1 - 0.061 13.0 0.1 0.061 13.0 0.1 2.3 2 1 0 2 2 2 0 Mating factor alpha precursor N-terminus DUF4625 PF15418.1 CEP11155.1 - 0.14 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) WD40 PF00400.27 CEP11156.1 - 5.3e-36 121.2 6.8 7.6e-08 31.9 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 CEP11156.1 - 7.3e-24 83.6 12.0 1.1e-23 83.0 8.3 1.3 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 CEP11156.1 - 2.1e-09 37.3 1.4 1.4e-06 28.1 0.1 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 CEP11156.1 - 5.8e-06 26.0 0.0 0.15 11.8 0.0 4.2 2 2 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 CEP11156.1 - 0.0046 15.7 1.4 2.9 6.5 0.2 3.8 2 1 0 3 3 3 1 Nup133 N terminal like PI3K_p85B PF02192.11 CEP11156.1 - 0.092 12.1 0.0 1.9 7.9 0.0 2.4 1 1 1 2 2 2 0 PI3-kinase family, p85-binding domain CUE PF02845.11 CEP11157.1 - 9.1e-11 41.0 0.2 1.8e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 CUE domain 60KD_IMP PF02096.15 CEP11157.1 - 0.24 11.0 0.6 0.48 10.0 0.4 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein RA PF00788.18 CEP11158.1 - 2.2e-12 47.2 0.0 1.8e-07 31.5 0.0 3.1 2 1 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 CEP11158.1 - 9e-08 31.3 0.0 2.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP11158.1 - 6.5e-05 22.4 0.0 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TUG-UBL1 PF11470.3 CEP11158.1 - 0.0025 17.7 0.1 0.5 10.3 0.0 3.1 2 0 0 2 2 2 1 GLUT4 regulating protein TUG SH3_3 PF08239.6 CEP11158.1 - 0.0046 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain PPR_2 PF13041.1 CEP11159.1 - 1.7e-64 213.5 22.1 1.7e-13 50.3 0.1 12.5 7 4 7 14 14 14 11 PPR repeat family PPR PF01535.15 CEP11159.1 - 1e-40 134.8 20.6 0.00029 20.5 0.0 14.5 16 0 0 16 16 16 8 PPR repeat PPR_3 PF13812.1 CEP11159.1 - 1.8e-39 130.7 14.7 1.9e-05 24.5 0.0 14.3 14 1 0 14 14 14 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEP11159.1 - 2.8e-35 119.4 18.1 0.00011 21.6 0.0 13.5 14 0 0 14 14 14 7 PPR repeat TPR_19 PF14559.1 CEP11159.1 - 0.00039 20.6 2.7 3.2 8.1 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.12 CEP11159.1 - 0.0074 16.5 0.8 17 5.7 0.0 4.3 5 0 0 5 5 5 1 Bacterial transcriptional activator domain DUF3430 PF11912.3 CEP11159.1 - 0.11 12.3 2.4 0.13 12.0 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3430) TPR_12 PF13424.1 CEP11159.1 - 0.52 10.2 8.4 6.7 6.7 0.2 5.1 5 2 2 7 7 7 0 Tetratricopeptide repeat DDE_3 PF13358.1 CEP11160.1 - 3.8e-19 68.8 0.6 6.1e-19 68.2 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP11160.1 - 2.4e-16 59.5 0.7 5.5e-16 58.3 0.5 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP11160.1 - 6.7e-10 39.1 0.6 1.2e-09 38.3 0.2 1.6 2 0 0 2 2 1 1 Winged helix-turn helix TrmB PF01978.14 CEP11160.1 - 7.2e-05 22.4 0.2 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.1 CEP11160.1 - 0.00012 21.5 0.0 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP11160.1 - 0.00016 22.4 1.7 0.00045 20.9 1.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP11160.1 - 0.00048 20.0 0.2 0.013 15.4 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 CEP11160.1 - 0.0005 19.3 0.1 0.076 12.4 0.0 3.1 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding KorB PF08535.5 CEP11160.1 - 0.0011 19.0 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 KorB domain HTH_7 PF02796.10 CEP11160.1 - 0.0012 18.6 1.2 0.051 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 CEP11160.1 - 0.0013 18.2 0.4 0.18 11.5 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain LacI PF00356.16 CEP11160.1 - 0.0032 17.0 0.2 0.21 11.2 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.5 CEP11160.1 - 0.026 14.1 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_17 PF12728.2 CEP11160.1 - 0.044 14.0 0.0 15 5.9 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.2 CEP11160.1 - 0.068 13.2 1.1 13 5.9 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain Mor PF08765.6 CEP11160.1 - 0.097 12.4 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family Heme_oxygenase PF01126.15 CEP11162.1 - 6.3e-56 189.1 1.8 8.4e-56 188.7 1.3 1.2 1 0 0 1 1 1 1 Heme oxygenase HsdM_N PF12161.3 CEP11162.1 - 0.0039 17.6 0.6 0.012 16.0 0.1 1.8 1 1 0 1 1 1 1 HsdM N-terminal domain BPL_N PF09825.4 CEP11163.1 - 4.2e-107 358.1 0.0 5.1e-107 357.8 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CEP11163.1 - 8.1e-18 64.6 0.0 1.8e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CEP11163.1 - 0.00021 20.9 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Peptidase_S51 PF03575.12 CEP11163.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 GATase_3 PF07685.9 CEP11163.1 - 0.038 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain hDGE_amylase PF14701.1 CEP11164.1 - 1.9e-158 527.8 0.0 2.7e-158 527.3 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CEP11164.1 - 2e-114 382.1 0.0 3.1e-114 381.5 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CEP11164.1 - 1.2e-70 237.7 0.0 1.7e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CEP11164.1 - 5.3e-12 45.4 0.0 1.3e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF4137 PF13593.1 CEP11165.1 - 8.9e-54 182.6 9.0 5.7e-48 163.6 4.0 2.1 2 0 0 2 2 2 2 SBF-like CPA transporter family (DUF4137) HTH_32 PF13565.1 CEP11165.1 - 0.00024 21.8 0.0 0.00076 20.2 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 CEP11165.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Transposase Cu_amine_oxid PF01179.15 CEP11167.1 - 1.1e-26 93.5 0.1 1.3e-26 93.2 0.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain PTPlike_phytase PF14566.1 CEP11168.1 - 1.1e-128 424.7 0.2 3.9e-42 143.8 0.0 3.5 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 CEP11168.1 - 1.7e-07 30.8 0.0 0.14 11.7 0.0 4.0 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP11168.1 - 0.00033 20.0 0.0 5.3 6.2 0.0 3.5 3 0 0 3 3 3 3 Protein-tyrosine phosphatase DUF2423 PF10338.4 CEP11168.1 - 0.21 11.5 2.2 11 6.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) Pkinase PF00069.20 CEP11169.1 - 1.8e-63 214.0 0.0 5.4e-63 212.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11169.1 - 5.4e-43 146.9 0.0 9.6e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP11169.1 - 5.3e-10 38.7 0.0 1.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP11169.1 - 0.0084 15.8 0.0 0.12 12.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tim17 PF02466.14 CEP11170.1 - 0.07 13.1 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF3650 PF12368.3 CEP11170.1 - 0.19 11.2 3.7 0.25 10.8 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) DUF4168 PF13767.1 CEP11170.1 - 1.6 9.4 4.3 1.4 9.5 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Glyco_hydro_47 PF01532.15 CEP11171.1 - 2.6e-143 477.9 2.1 3e-143 477.7 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CotH PF08757.6 CEP11172.1 - 3.4e-07 29.8 0.0 4.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 CotH protein CotH PF08757.6 CEP11173.1 - 1.5e-10 40.8 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 CotH protein MSA-2c PF12238.3 CEP11175.1 - 0.25 11.0 4.5 0.32 10.6 3.2 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Macoilin PF09726.4 CEP11175.1 - 0.32 9.2 7.7 0.39 8.9 5.3 1.0 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 CEP11175.1 - 0.77 7.6 11.5 0.86 7.5 7.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RAP1 PF07218.6 CEP11175.1 - 1 7.3 9.5 1.2 7.1 6.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_C12 PF01088.16 CEP11176.1 - 2.8e-65 219.4 0.1 3.2e-65 219.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUZ PF12752.2 CEP11177.1 - 5.8e-14 52.3 2.3 5.8e-14 52.3 1.6 2.1 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 CEP11177.1 - 2.8e-11 42.9 1.1 6.7e-11 41.7 0.2 2.1 2 0 0 2 2 2 1 R3H domain AA_permease PF00324.16 CEP11178.1 - 1.3e-136 455.8 42.3 1.5e-136 455.5 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEP11178.1 - 3e-45 154.5 44.6 3.5e-45 154.3 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease Brr6_like_C_C PF10104.4 CEP11179.1 - 5.3e-23 81.0 1.5 8.6e-23 80.3 1.0 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain LAT PF15234.1 CEP11179.1 - 0.0095 15.4 1.0 0.015 14.7 0.7 1.3 1 0 0 1 1 1 1 Linker for activation of T-cells DDDD PF10161.4 CEP11179.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative mitochondrial precursor protein DUF3884 PF13024.1 CEP11180.1 - 0.03 13.7 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Coprogen_oxidas PF01218.13 CEP11181.1 - 9.1e-131 434.7 0.2 1.1e-130 434.5 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Hydantoinase_B PF02538.9 CEP11182.1 - 2.4e-193 643.1 0.3 3.1e-193 642.7 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CEP11182.1 - 3.7e-92 308.5 0.0 3.7e-92 308.5 0.0 2.8 4 0 0 4 4 4 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CEP11182.1 - 5.9e-34 117.0 0.2 3e-20 72.4 0.0 3.8 3 1 1 4 4 4 3 Hydantoinase/oxoprolinase N-terminal region Spidroin_MaSp PF11260.3 CEP11182.1 - 0.046 13.8 0.2 2.3 8.3 0.0 2.9 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 Fungal_trans PF04082.13 CEP11184.1 - 2.8e-35 121.4 0.8 1.9e-34 118.7 0.0 2.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP11184.1 - 4.1e-10 39.3 12.5 4.1e-10 39.3 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 CEP11185.1 - 2.7e-97 322.0 0.0 2.2e-47 160.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CEP11185.1 - 4.3e-18 65.0 1.1 3.5e-17 62.1 0.5 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CEP11185.1 - 1e-13 50.9 0.1 2.7e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CEP11185.1 - 4.7e-13 49.4 0.0 2.6e-07 30.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CEP11185.1 - 1.6e-12 47.5 0.0 6e-06 26.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEP11185.1 - 4.1e-12 46.9 0.1 0.00011 22.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 CEP11185.1 - 5.6e-12 45.5 0.6 1.4e-05 24.8 0.0 4.2 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CEP11185.1 - 1.7e-11 44.3 0.1 0.002 18.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 CEP11185.1 - 7.9e-11 41.4 0.0 2.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 CEP11185.1 - 6.3e-10 39.3 0.1 0.0018 18.2 0.0 3.4 3 2 1 4 4 2 2 AAA ATPase domain TIP49 PF06068.8 CEP11185.1 - 1.8e-09 36.8 0.2 0.00074 18.3 0.0 2.8 2 1 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 CEP11185.1 - 2.9e-08 33.3 0.0 0.0037 16.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 CEP11185.1 - 6e-08 32.0 0.0 0.0092 15.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 CEP11185.1 - 1.1e-07 31.5 1.2 0.009 15.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 CEP11185.1 - 2.3e-07 30.1 0.2 0.018 14.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CEP11185.1 - 2.8e-07 30.9 0.0 0.034 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CEP11185.1 - 3e-07 30.3 0.0 0.0083 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CEP11185.1 - 3.3e-07 29.9 3.0 0.022 14.1 0.0 3.9 2 2 2 4 4 4 2 AAA domain ABC_tran PF00005.22 CEP11185.1 - 1.8e-06 28.2 0.0 0.034 14.4 0.0 3.9 3 1 0 3 3 2 2 ABC transporter RNA_helicase PF00910.17 CEP11185.1 - 2e-06 27.9 0.0 0.017 15.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 CEP11185.1 - 2.3e-06 27.6 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 CEP11185.1 - 4.8e-06 25.6 0.1 0.0088 14.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 CEP11185.1 - 4.9e-06 26.5 0.0 0.0061 16.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 CEP11185.1 - 9e-06 25.2 0.0 0.26 10.7 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 CEP11185.1 - 1.5e-05 24.2 1.0 0.97 8.5 0.0 3.5 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 CEP11185.1 - 3.1e-05 23.0 0.0 0.0061 15.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 CEP11185.1 - 3.4e-05 23.1 0.2 0.24 10.6 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein Vps4_C PF09336.5 CEP11185.1 - 4e-05 23.4 0.0 0.00047 19.9 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 CEP11185.1 - 5.8e-05 22.7 0.1 0.11 12.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 CEP11185.1 - 6.8e-05 22.9 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 CEP11185.1 - 7.7e-05 22.4 0.0 2.6 7.6 0.0 3.5 2 1 1 3 3 3 1 Archaeal ATPase Bac_DnaA PF00308.13 CEP11185.1 - 0.00018 21.2 0.0 0.81 9.2 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein DUF2075 PF09848.4 CEP11185.1 - 0.00022 20.2 0.0 0.38 9.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 CEP11185.1 - 0.00023 20.7 0.0 0.6 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CEP11185.1 - 0.00033 20.3 0.0 0.49 9.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 CEP11185.1 - 0.00036 20.2 0.1 0.52 9.9 0.0 3.4 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.17 CEP11185.1 - 0.0016 17.3 0.0 0.27 10.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 CEP11185.1 - 0.0023 17.5 0.0 0.98 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CEP11185.1 - 0.0027 17.4 0.5 1.2 8.8 0.0 3.7 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 CEP11185.1 - 0.0054 16.2 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CEP11185.1 - 0.0092 14.9 0.0 0.56 9.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein SKI PF01202.17 CEP11185.1 - 0.017 14.9 0.0 7.7 6.3 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AAA_10 PF12846.2 CEP11185.1 - 0.029 13.8 1.2 5.2 6.4 0.0 3.8 3 1 1 4 4 4 0 AAA-like domain ATP-synt_ab PF00006.20 CEP11185.1 - 0.034 13.6 0.0 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin2 PF13189.1 CEP11185.1 - 0.042 13.7 0.0 0.95 9.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family KTI12 PF08433.5 CEP11185.1 - 0.065 12.4 0.0 7.6 5.6 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 CEP11185.1 - 0.075 12.6 0.1 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 CEP11185.1 - 0.096 11.8 0.1 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_23 PF13476.1 CEP11185.1 - 0.1 12.8 0.5 4.4 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Zot PF05707.7 CEP11185.1 - 0.13 11.7 0.1 18 4.7 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) RVT_1 PF00078.22 CEP11186.1 - 0.00033 20.0 0.0 0.00037 19.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_U47 PF05467.6 CEP11186.1 - 0.01 13.7 1.2 0.013 13.3 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 HIT PF01230.18 CEP11187.1 - 1.4e-14 54.3 0.0 2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CEP11187.1 - 5.3e-05 23.4 0.0 8.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PH PF00169.24 CEP11188.1 - 4.8e-08 33.1 0.1 1.1e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 PH domain RolB_RolC PF02027.12 CEP11188.1 - 0.043 12.9 0.1 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 RolB/RolC glucosidase family Kinesin PF00225.18 CEP11189.1 - 1.8e-98 329.3 2.0 1.8e-98 329.3 1.4 2.0 2 0 0 2 2 2 1 Kinesin motor domain Nexin_C PF08628.7 CEP11189.1 - 0.16 12.0 2.7 0.59 10.2 1.9 2.0 1 0 0 1 1 1 0 Sorting nexin C terminal Folate_carrier PF01770.13 CEP11189.1 - 1.1 7.7 2.0 2 6.8 1.4 1.3 1 0 0 1 1 1 0 Reduced folate carrier Pyridoxal_deC PF00282.14 CEP11190.1 - 8e-77 258.1 0.0 1.1e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CEP11190.1 - 1.6e-05 23.8 0.0 2.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CEP11190.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cation_efflux PF01545.16 CEP11191.1 - 1.2e-69 234.5 9.8 1.5e-69 234.2 6.8 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 CEP11191.1 - 1.1e-06 27.8 0.9 8.1e-05 21.7 0.0 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter EPL1 PF10513.4 CEP11191.1 - 0.075 13.2 0.7 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2838 PF10998.3 CEP11192.1 - 1.1e-35 121.9 10.3 1.1e-35 121.9 7.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Ribosomal_S28e PF01200.13 CEP11193.1 - 5.1e-34 115.8 1.6 6e-34 115.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e ADIP PF11559.3 CEP11194.1 - 1.5e-22 80.0 15.9 1.5e-22 80.0 11.0 3.7 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding DUF3113 PF11310.3 CEP11194.1 - 0.1 12.2 1.1 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Prp19 PF08606.6 CEP11194.1 - 3 7.6 10.1 1 9.1 0.4 3.6 4 0 0 4 4 4 0 Prp19/Pso4-like Mso1_Sec1_bdg PF14475.1 CEP11195.1 - 1.1e-05 24.7 0.0 2.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Sec1-binding region of Mso1 FAA_hydrolase PF01557.13 CEP11196.1 - 1.1e-51 175.3 0.0 1.5e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 CEP11196.1 - 1.4e-33 115.1 0.0 5.3e-33 113.2 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Glyco_hydro_15 PF00723.16 CEP11197.1 - 3.1e-59 200.7 0.0 8.2e-58 196.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Methyltransf_11 PF08241.7 CEP11200.1 - 7.1e-17 61.6 0.0 2.6e-13 50.2 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 CEP11200.1 - 2.3e-14 53.4 0.1 7.1e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP11200.1 - 3.8e-12 46.0 0.0 1.9e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP11200.1 - 1.2e-10 42.0 0.0 4.3e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP11200.1 - 4.6e-09 36.6 0.0 1.6e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP11200.1 - 2.9e-08 33.9 0.0 7.4e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CEP11200.1 - 1.3e-06 28.5 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 CEP11200.1 - 1.5e-05 24.1 0.0 0.00026 20.1 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 CEP11200.1 - 0.00012 22.0 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP11200.1 - 0.0017 17.4 0.0 0.0095 15.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CEP11200.1 - 0.0036 16.6 0.0 0.0072 15.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 CEP11200.1 - 0.012 14.7 0.0 0.026 13.5 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 CEP11200.1 - 0.094 11.8 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase PRCH PF03967.8 CEP11200.1 - 0.11 12.1 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region Methyltransf_9 PF08003.6 CEP11200.1 - 0.14 10.7 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Grp1_Fun34_YaaH PF01184.14 CEP11201.1 - 6.6e-24 84.3 19.7 9.9e-24 83.8 13.7 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TLV_coat PF00429.14 CEP11201.1 - 0.0096 14.4 0.6 0.012 14.0 0.4 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) DUF373 PF04123.8 CEP11201.1 - 0.18 10.7 1.0 0.24 10.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) BBS2_Mid PF14783.1 CEP11202.1 - 0.00027 20.6 0.1 0.6 9.9 0.0 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 CEP11202.1 - 0.0048 16.5 3.0 1.5 8.5 0.3 2.9 2 0 0 2 2 2 2 FG-GAP repeat LRR_4 PF12799.2 CEP11205.1 - 0.63 9.7 2.6 1.8 8.2 1.8 1.7 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Chromo PF00385.19 CEP11206.1 - 9.6e-07 28.3 0.1 1.4e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 CEP11206.1 - 0.1 12.3 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC PF00098.18 CEP11207.1 - 5.2e-07 29.2 10.4 0.0027 17.5 1.7 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP11207.1 - 0.0022 17.5 8.5 0.04 13.5 0.4 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP11207.1 - 0.004 16.6 8.0 0.058 12.9 0.7 2.5 1 1 1 2 2 2 2 Zinc knuckle Exo_endo_phos_2 PF14529.1 CEP11209.1 - 1e-11 44.4 0.3 3.5e-11 42.7 0.2 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP11209.1 - 0.036 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.14 CEP11210.1 - 4.3e-10 39.8 0.8 4.8e-09 36.5 0.3 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.15 CEP11210.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 RVT_1 PF00078.22 CEP11211.1 - 1.7e-05 24.2 0.1 2.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1675 PF07897.6 CEP11212.1 - 0.51 10.1 4.0 0.66 9.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Menin PF05053.8 CEP11212.1 - 3.9 5.5 6.5 4.1 5.4 4.5 1.1 1 0 0 1 1 1 0 Menin DUF2454 PF10521.4 CEP11213.1 - 4.3e-27 94.8 1.2 7.2e-26 90.8 0.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) CDP-OH_P_transf PF01066.16 CEP11214.1 - 6.3e-18 64.9 6.8 1.4e-17 63.8 4.7 1.8 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF2177 PF09945.4 CEP11214.1 - 0.1 12.6 0.2 0.1 12.6 0.1 2.7 2 1 0 3 3 3 0 Predicted membrane protein (DUF2177) Pyr_redox_2 PF07992.9 CEP11215.1 - 9.2e-05 22.4 0.0 0.0027 17.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP11215.1 - 0.00023 21.3 0.0 0.25 11.3 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP11215.1 - 0.00067 19.4 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF2674 PF10879.3 CEP11215.1 - 0.0031 17.2 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2674) NAD_binding_8 PF13450.1 CEP11215.1 - 0.0036 17.2 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF3808 PF10300.4 CEP11216.1 - 1.1e-64 218.7 9.8 1.9e-64 217.9 6.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 CEP11216.1 - 0.0025 17.6 0.9 2 8.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP11216.1 - 0.0073 16.2 0.1 4 7.4 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF1151 PF06625.6 CEP11216.1 - 0.12 12.1 4.3 0.094 12.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) MutL_C PF08676.6 CEP11217.1 - 1.2e-11 44.4 0.1 1.2e-07 31.4 0.1 2.4 2 0 0 2 2 2 2 MutL C terminal dimerisation domain DUF1722 PF08349.6 CEP11217.1 - 0.023 14.5 0.4 0.25 11.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) Phage_tail_L PF05100.7 CEP11217.1 - 0.081 12.0 0.1 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein L DNA_pol3_delt_C PF14840.1 CEP11217.1 - 0.1 12.6 0.6 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term GDC-P PF02347.11 CEP11218.1 - 6.1e-202 670.9 1.4 1.6e-188 626.7 0.1 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CEP11218.1 - 5.7e-08 31.8 1.4 1.7e-06 27.0 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 CEP11218.1 - 9.3e-06 24.9 2.6 9.8e-06 24.9 0.2 2.1 3 0 0 3 3 3 1 Beta-eliminating lyase BCDHK_Adom3 PF10436.4 CEP11219.1 - 8.3e-53 178.2 0.2 3e-52 176.4 0.1 1.8 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Methyltransf_11 PF08241.7 CEP11219.1 - 3.6e-15 56.2 0.0 7.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP11219.1 - 1.2e-12 47.6 0.0 7.2e-12 45.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain HATPase_c PF02518.21 CEP11219.1 - 6.4e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_23 PF13489.1 CEP11219.1 - 2.8e-10 40.1 0.0 5.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP11219.1 - 1.6e-09 38.0 0.0 4.8e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CEP11219.1 - 9.1e-09 35.2 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 CEP11219.1 - 1.5e-08 35.2 0.0 3.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP11219.1 - 8.4e-08 31.6 0.0 3.1e-07 29.7 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CEP11219.1 - 1.6e-06 28.5 0.0 4.6e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP11219.1 - 6.6e-06 26.1 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP11219.1 - 1.6e-05 24.0 0.0 8.2e-05 21.7 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase HATPase_c_3 PF13589.1 CEP11219.1 - 0.00012 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_2 PF00891.13 CEP11219.1 - 0.0032 16.6 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 CEP11219.1 - 0.01 15.8 0.0 0.041 13.8 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 CEP11219.1 - 0.025 13.9 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Crust_neurohorm PF01147.12 CEP11219.1 - 0.081 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Glyco_hydro_31 PF01055.21 CEP11220.1 - 2.6e-162 540.6 6.4 3.4e-162 540.2 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CEP11220.1 - 1.3e-06 28.1 0.7 3.5e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like CAP_GLY PF01302.20 CEP11221.1 - 6.2e-17 61.0 0.1 9.1e-17 60.5 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain HLH PF00010.21 CEP11222.1 - 8.3e-14 51.0 1.1 2e-13 49.7 0.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ins_allergen_rp PF06757.8 CEP11222.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Glycogen_syn PF05693.8 CEP11222.1 - 0.04 12.1 0.7 0.049 11.8 0.5 1.0 1 0 0 1 1 1 0 Glycogen synthase V_ATPase_I PF01496.14 CEP11222.1 - 0.14 10.0 1.1 0.16 9.7 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nnf1 PF03980.9 CEP11223.1 - 2.3e-05 24.3 1.1 2.3e-05 24.3 0.8 1.7 2 0 0 2 2 2 1 Nnf1 EspA PF03433.8 CEP11223.1 - 0.0035 16.7 0.5 0.0062 15.9 0.3 1.4 1 1 0 1 1 1 1 EspA-like secreted protein MCPsignal PF00015.16 CEP11223.1 - 0.03 13.8 0.1 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BCDHK_Adom3 PF10436.4 CEP11223.1 - 0.045 13.2 0.5 0.64 9.5 0.4 2.0 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Dimer_Tnp_Tn5 PF02281.11 CEP11223.1 - 0.2 11.8 0.6 9.2 6.4 0.1 2.3 1 1 1 2 2 2 0 Transposase Tn5 dimerisation domain LOH1CR12 PF10158.4 CEP11223.1 - 0.2 11.4 1.8 0.37 10.5 1.1 1.7 1 1 1 2 2 2 0 Tumour suppressor protein DUF4200 PF13863.1 CEP11223.1 - 0.35 10.8 6.9 0.74 9.7 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Laps PF10169.4 CEP11223.1 - 1.8 8.7 5.6 0.24 11.6 0.9 1.8 2 1 0 2 2 2 0 Learning-associated protein CI-B14_5a PF07347.7 CEP11224.1 - 0.00027 20.6 0.4 0.001 18.7 0.2 1.9 1 1 1 2 2 2 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF2780 PF11075.3 CEP11224.1 - 0.11 12.4 0.5 0.15 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) Mito_carr PF00153.22 CEP11225.1 - 1.5e-74 245.7 0.2 4.1e-25 87.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sas10_Utp3 PF04000.10 CEP11226.1 - 0.0014 18.7 2.5 0.0026 17.9 0.0 2.4 2 1 1 3 3 3 1 Sas10/Utp3/C1D family FancD2 PF14631.1 CEP11226.1 - 0.057 10.5 4.8 0.07 10.2 3.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PMSI1 PF15322.1 CEP11226.1 - 0.13 11.3 1.7 0.15 11.1 1.2 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF2457 PF10446.4 CEP11226.1 - 0.16 10.6 8.0 0.21 10.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Phyto_Pns9_10 PF05878.6 CEP11226.1 - 0.17 10.8 3.3 0.22 10.4 2.3 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF2052 PF09747.4 CEP11226.1 - 0.26 11.2 6.4 0.36 10.7 4.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FLO_LFY PF01698.11 CEP11226.1 - 0.3 9.9 7.0 0.37 9.5 4.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF755 PF05501.6 CEP11226.1 - 0.74 9.8 5.9 1.5 8.8 4.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF755) TP53IP5 PF15331.1 CEP11226.1 - 2.6 7.9 5.7 3.1 7.6 4.0 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 EST1 PF10374.4 CEP11227.1 - 0.04 13.8 4.1 0.78 9.7 0.7 3.4 1 1 1 2 2 2 0 Telomerase activating protein Est1 IPT PF01745.11 CEP11227.1 - 0.043 12.9 3.3 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase GNAT_acetyltr_2 PF13718.1 CEP11228.1 - 1e-82 276.2 0.0 2e-82 275.2 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CEP11228.1 - 1.4e-66 223.4 0.0 3.8e-66 222.0 0.0 1.8 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 CEP11228.1 - 1.3e-39 133.7 0.1 3.5e-39 132.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CEP11228.1 - 7.7e-34 115.8 0.1 2.6e-33 114.1 0.0 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CEP11228.1 - 0.0017 18.5 0.0 0.012 15.7 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DEAD PF00270.24 CEP11228.1 - 0.024 14.1 0.1 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Acetyltransf_1 PF00583.19 CEP11228.1 - 0.062 13.3 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family GMC_oxred_N PF00732.14 CEP11229.1 - 1e-37 129.9 0.1 2.7e-37 128.5 0.1 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEP11229.1 - 6.3e-20 71.9 0.1 1.2e-19 71.0 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CEP11229.1 - 6.8e-08 31.7 3.4 7.3e-05 21.7 1.2 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 CEP11229.1 - 2.4e-05 23.4 0.3 0.00043 19.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEP11229.1 - 0.00017 21.5 0.7 0.004 17.0 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP11229.1 - 0.0058 16.6 1.9 0.0058 16.6 1.3 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 CEP11229.1 - 0.018 14.8 0.0 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 CEP11229.1 - 0.024 13.7 0.1 0.055 12.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 CEP11229.1 - 0.048 12.5 0.4 0.078 11.8 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 CEP11229.1 - 0.057 11.8 1.5 0.071 11.5 0.4 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 CEP11229.1 - 0.12 11.4 0.4 0.19 10.7 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 CEP11229.1 - 1.7 7.6 5.8 0.5 9.3 2.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 CEP11230.1 - 5.2e-34 117.7 2.0 3.9e-20 72.1 0.8 3.0 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.8 CEP11230.1 - 1.1e-21 77.6 0.0 6e-21 75.2 0.0 2.3 1 0 0 1 1 1 1 GMC oxidoreductase HLH PF00010.21 CEP11230.1 - 6.6e-12 44.9 0.2 1.6e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAD_binding_2 PF00890.19 CEP11230.1 - 2.7e-10 39.6 3.1 8.4e-07 28.1 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 CEP11230.1 - 1e-08 35.3 0.1 6.5e-05 22.8 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP11230.1 - 2.3e-08 33.3 2.0 3.1e-05 23.0 0.4 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP11230.1 - 2.1e-06 27.6 0.6 1.4e-05 24.9 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CEP11230.1 - 0.00027 20.1 0.4 0.00058 19.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CEP11230.1 - 0.00098 18.2 1.0 0.0033 16.5 0.5 2.0 1 1 1 2 2 2 1 Thi4 family HI0933_like PF03486.9 CEP11230.1 - 0.0013 17.3 0.6 0.0013 17.3 0.4 2.5 3 0 0 3 3 2 1 HI0933-like protein FAD_oxidored PF12831.2 CEP11230.1 - 0.0018 17.4 3.3 0.0041 16.2 2.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CEP11230.1 - 0.0048 15.8 0.4 0.0048 15.8 0.2 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A ApbA PF02558.11 CEP11230.1 - 0.013 14.9 0.1 0.036 13.5 0.1 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 CEP11230.1 - 0.014 13.7 0.1 0.029 12.7 0.1 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 CEP11230.1 - 0.02 13.8 0.1 0.055 12.3 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 CEP11230.1 - 0.2 11.4 1.2 0.6 9.9 0.8 1.8 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 CEP11230.1 - 0.39 10.3 2.6 0.76 9.4 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ArfGap PF01412.13 CEP11231.1 - 5.4e-22 77.7 0.2 1.7e-21 76.1 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Complex1_30kDa PF00329.14 CEP11232.1 - 6.1e-36 122.7 0.0 9.2e-36 122.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Syntaxin-18_N PF10496.4 CEP11234.1 - 8.8e-15 54.3 1.8 8.8e-15 54.3 1.2 3.2 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus CENP-K PF11802.3 CEP11234.1 - 0.017 14.3 11.9 0.041 13.1 8.2 1.7 1 0 0 1 1 1 0 Centromere-associated protein K NlpE PF04170.7 CEP11234.1 - 0.57 10.6 4.3 1.9 8.9 3.0 1.9 1 0 0 1 1 1 0 NlpE N-terminal domain CBFB_NFYA PF02045.10 CEP11234.1 - 1.3 9.6 6.9 23 5.6 2.0 3.1 2 1 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B YjgP_YjgQ PF03739.9 CEP11234.1 - 5.7 5.5 9.8 9.4 4.8 0.0 2.4 1 1 0 2 2 2 0 Predicted permease YjgP/YjgQ family E1-E2_ATPase PF00122.15 CEP11235.1 - 1.4e-28 99.5 0.2 2.7e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CEP11235.1 - 8.9e-26 91.2 0.0 1.6e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 CEP11235.1 - 7.8e-22 77.3 0.4 2.1e-21 75.9 0.3 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.21 CEP11235.1 - 8.7e-15 55.7 0.0 8.7e-13 49.1 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP11235.1 - 3.8e-05 23.5 0.0 9.7e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CEP11235.1 - 0.00012 21.4 0.0 0.00035 19.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP11235.1 - 0.051 13.1 0.2 13 5.2 0.1 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Daxx PF03344.10 CEP11235.1 - 8.9 4.6 9.9 13 4.0 6.9 1.1 1 0 0 1 1 1 0 Daxx Family Striatin PF08232.7 CEP11236.1 - 0.022 15.0 0.4 0.022 15.0 0.3 3.3 2 1 1 3 3 3 0 Striatin family PAT1 PF09770.4 CEP11236.1 - 0.043 12.0 41.1 0.057 11.6 28.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0560 PF10577.4 CEP11236.1 - 0.098 10.9 21.4 0.16 10.2 14.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SelP_N PF04592.9 CEP11236.1 - 0.13 11.6 23.6 0.44 9.9 16.3 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4175 PF13779.1 CEP11236.1 - 0.26 8.9 32.6 0.48 8.0 22.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tfb4 PF03850.9 CEP11236.1 - 1.8 7.7 18.2 1.1 8.4 0.7 2.3 1 1 1 2 2 2 0 Transcription factor Tfb4 FHIPEP PF00771.15 CEP11236.1 - 4.4 5.5 6.5 6.6 4.9 4.5 1.3 1 0 0 1 1 1 0 FHIPEP family OATP PF03137.15 CEP11236.1 - 6.6 4.6 5.8 10 4.0 4.0 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Chromo PF00385.19 CEP11239.1 - 2e-10 40.1 0.8 3.7e-10 39.3 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP11239.1 - 0.00034 20.2 1.6 0.0018 17.9 0.2 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RuBisCO_small PF00101.15 CEP11239.1 - 0.11 12.3 0.2 0.21 11.4 0.1 1.4 1 1 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain zf-CCHC_6 PF15288.1 CEP11241.1 - 0.15 11.7 1.2 0.26 11.0 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle RabGAP-TBC PF00566.13 CEP11243.1 - 2.7e-39 134.8 4.0 1.1e-25 90.3 0.1 3.3 2 1 1 3 3 3 2 Rab-GTPase-TBC domain GRAM PF02893.15 CEP11243.1 - 9.9e-10 37.8 0.9 4.6e-09 35.6 0.1 2.4 2 0 0 2 2 2 1 GRAM domain DUF1476 PF07345.6 CEP11243.1 - 0.029 14.6 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1476) EF-hand_6 PF13405.1 CEP11243.1 - 0.042 13.7 0.2 0.27 11.2 0.2 2.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 CEP11243.1 - 0.07 13.2 2.1 0.45 10.6 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain pair DUF4032 PF13224.1 CEP11244.1 - 0.051 13.2 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) LMP PF04778.7 CEP11244.1 - 0.057 13.1 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 LMP repeated region TBPIP PF07106.8 CEP11244.1 - 0.078 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MRP-S31 PF15433.1 CEP11244.1 - 0.079 12.3 0.1 0.097 12.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DNA_pol_A_exo1 PF01612.15 CEP11245.1 - 6.5e-11 42.0 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease RVT_1 PF00078.22 CEP11246.1 - 2.4e-27 95.6 0.0 2.9e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) M20_dimer PF07687.9 CEP11247.1 - 1.7e-10 40.6 0.0 4.2e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 CEP11247.1 - 4e-09 36.2 0.0 1.2e-08 34.6 0.0 1.7 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 p450 PF00067.17 CEP11248.1 - 4.8e-78 262.7 0.0 5.9e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4536 PF15055.1 CEP11248.1 - 0.047 13.7 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Cyclin_N PF00134.18 CEP11249.1 - 7.9e-09 35.1 0.0 1.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CEP11249.1 - 5.1e-07 30.2 0.0 7.4e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Cyclin Ribosomal_L7Ae PF01248.21 CEP11250.1 - 1.3e-22 79.0 1.4 2.5e-22 78.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L18ae PF01775.12 CEP11251.1 - 3.6e-54 181.9 2.9 4.7e-54 181.5 2.0 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain AAA PF00004.24 CEP11252.1 - 5.5e-97 321.0 0.0 4e-49 166.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEP11252.1 - 2e-17 63.0 0.0 2.8e-10 39.6 0.0 2.6 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CEP11252.1 - 1.8e-12 47.1 0.7 0.00014 21.6 0.0 4.7 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP11252.1 - 6.7e-12 45.7 2.6 0.00026 21.0 0.1 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 CEP11252.1 - 2.5e-11 44.4 0.0 5.3e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CEP11252.1 - 3.5e-11 43.3 0.3 0.0036 17.4 0.0 4.7 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.9 CEP11252.1 - 4.5e-11 42.9 0.0 0.0001 22.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CEP11252.1 - 3.3e-10 40.0 0.0 0.00017 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CEP11252.1 - 6.2e-10 38.4 0.0 0.00073 18.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 CEP11252.1 - 8.5e-10 38.6 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CEP11252.1 - 4.5e-09 35.5 0.0 0.00011 21.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 CEP11252.1 - 8.4e-09 35.0 4.6 0.33 10.3 0.0 4.7 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.17 CEP11252.1 - 6.8e-08 32.6 0.0 0.018 15.1 0.0 3.1 2 1 0 2 2 2 2 RNA helicase NACHT PF05729.7 CEP11252.1 - 7.1e-08 32.2 1.1 0.095 12.3 0.0 4.6 4 1 1 5 5 4 2 NACHT domain AAA_19 PF13245.1 CEP11252.1 - 8.3e-08 31.8 1.9 0.0081 15.8 0.0 3.8 4 0 0 4 4 3 2 Part of AAA domain IstB_IS21 PF01695.12 CEP11252.1 - 2e-07 30.5 0.2 0.016 14.6 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 CEP11252.1 - 2.5e-06 27.5 0.0 0.087 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CEP11252.1 - 4.1e-06 27.1 0.0 0.031 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CEP11252.1 - 5.5e-06 25.6 0.3 0.054 12.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.1 CEP11252.1 - 7.7e-06 25.9 0.0 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 CEP11252.1 - 1.7e-05 24.7 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 Shikimate kinase ABC_tran PF00005.22 CEP11252.1 - 2.2e-05 24.7 0.0 0.39 11.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter Arch_ATPase PF01637.13 CEP11252.1 - 2.2e-05 24.2 0.0 2.5 7.7 0.0 3.9 2 2 2 4 4 3 1 Archaeal ATPase Sigma54_activat PF00158.21 CEP11252.1 - 4.5e-05 22.9 0.0 0.2 11.1 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain KaiC PF06745.8 CEP11252.1 - 6.2e-05 22.2 0.0 0.85 8.6 0.0 3.4 3 0 0 3 3 3 1 KaiC ATP-synt_ab PF00006.20 CEP11252.1 - 7.2e-05 22.3 0.0 0.47 9.9 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 CEP11252.1 - 8.1e-05 21.6 0.0 0.017 14.0 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 CEP11252.1 - 8.6e-05 22.1 0.0 0.24 11.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CEP11252.1 - 0.00032 19.6 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.1 CEP11252.1 - 0.00037 20.5 0.0 0.27 11.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CEP11252.1 - 0.00049 19.6 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 CEP11252.1 - 0.0013 18.3 0.0 0.73 9.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CEP11252.1 - 0.0016 17.3 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 CEP11252.1 - 0.0018 17.9 0.0 1.1 8.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.10 CEP11252.1 - 0.0027 16.4 0.0 1.4 7.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Bac_DnaA PF00308.13 CEP11252.1 - 0.0038 16.8 0.0 4.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein PhoH PF02562.11 CEP11252.1 - 0.004 16.3 0.2 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein CPT PF07931.7 CEP11252.1 - 0.005 16.4 0.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AFG1_ATPase PF03969.11 CEP11252.1 - 0.012 14.4 0.0 4.5 5.9 0.0 2.7 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.10 CEP11252.1 - 0.012 15.3 2.7 3.6 7.2 0.0 3.6 4 0 0 4 4 4 0 NTPase PduV-EutP PF10662.4 CEP11252.1 - 0.013 14.9 0.0 10 5.6 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 CEP11252.1 - 0.016 15.0 0.0 3 7.6 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 CEP11252.1 - 0.035 13.6 2.0 1.1 8.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain KCl_Cotrans_1 PF03522.10 CEP11252.1 - 0.065 12.7 0.9 0.16 11.5 0.6 1.6 1 0 0 1 1 1 0 K-Cl Co-transporter type 1 (KCC1) F-box-like PF12937.2 CEP11253.1 - 2e-05 24.1 0.3 5e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP11253.1 - 0.088 12.4 0.9 0.23 11.1 0.6 1.8 1 0 0 1 1 1 0 F-box domain TPR_1 PF00515.23 CEP11254.1 - 9.7e-15 53.4 7.6 0.0044 16.5 0.0 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP11254.1 - 1.3e-14 54.3 7.1 0.001 19.6 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP11254.1 - 2.9e-14 52.2 15.3 0.0042 17.5 0.1 9.2 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 CEP11254.1 - 1.5e-13 50.1 0.1 0.00029 20.4 0.0 7.8 6 3 3 10 10 10 5 TPR repeat TPR_19 PF14559.1 CEP11254.1 - 6.4e-12 45.6 14.8 2.3e-05 24.6 0.0 7.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP11254.1 - 8.6e-10 37.7 12.0 0.043 13.7 0.0 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP11254.1 - 5.5e-08 32.4 8.4 1.5 9.1 0.1 8.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEP11254.1 - 4.1e-07 29.3 6.8 0.089 12.6 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11254.1 - 2.5e-06 26.8 2.0 4.9 7.1 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CEP11254.1 - 8.6e-05 22.5 23.4 0.86 9.7 0.0 7.1 5 3 4 9 9 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 CEP11254.1 - 0.00054 20.0 1.4 0.13 12.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP11254.1 - 0.004 17.0 16.3 0.82 9.6 0.0 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 CEP11254.1 - 0.0051 17.1 6.1 10 6.8 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.4 CEP11254.1 - 0.013 14.8 0.0 2.1 7.7 0.0 2.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 zf-RING_5 PF14634.1 CEP11255.1 - 0.024 14.3 8.5 0.024 14.3 5.9 3.9 3 1 0 3 3 3 0 zinc-RING finger domain IBR PF01485.16 CEP11255.1 - 1.7 8.5 38.3 2.4 8.1 0.2 4.8 2 1 1 3 3 3 0 IBR domain Cu_amine_oxid PF01179.15 CEP11256.1 - 2.8e-33 115.2 0.7 6.8e-33 113.9 0.5 1.6 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.15 CEP11257.1 - 6.9e-25 87.6 0.0 7.9e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain rve PF00665.21 CEP11259.1 - 1.4e-20 73.5 0.0 2.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP11259.1 - 9.1e-15 54.0 0.4 1.7e-14 53.2 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP11259.1 - 0.012 14.9 0.0 0.031 13.6 0.0 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger KCl_Cotrans_1 PF03522.10 CEP11261.1 - 0.0057 16.1 0.3 0.0057 16.1 0.2 3.0 3 0 0 3 3 3 1 K-Cl Co-transporter type 1 (KCC1) Rho_GDI PF02115.12 CEP11261.1 - 0.068 12.5 0.1 0.094 12.1 0.1 1.2 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Pox_polyA_pol_N PF12630.2 CEP11261.1 - 0.075 13.1 1.2 0.13 12.3 0.9 1.4 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Orbi_VP5 PF00901.12 CEP11261.1 - 0.086 11.0 0.4 0.1 10.7 0.3 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Helitron_like_N PF14214.1 CEP11262.1 - 1.2e-16 60.9 0.2 2.2e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phe_ZIP PF08916.6 CEP11262.1 - 0.0004 20.6 0.3 0.03 14.6 0.1 2.5 2 0 0 2 2 2 1 Phenylalanine zipper IL4Ra_N PF09238.5 CEP11262.1 - 0.15 12.1 2.0 0.29 11.2 0.8 1.9 2 0 0 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal ABC2_membrane_2 PF12679.2 CEP11265.1 - 0.0033 16.3 4.8 0.0034 16.2 3.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF677 PF05055.7 CEP11265.1 - 0.035 12.7 3.6 0.045 12.4 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF677) FA_desaturase PF00487.19 CEP11265.1 - 0.32 10.3 3.1 0.39 10.1 2.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase IncA PF04156.9 CEP11265.1 - 0.69 9.4 3.3 0.83 9.2 2.3 1.2 1 0 0 1 1 1 0 IncA protein GAGA PF09237.6 CEP11266.1 - 0.27 10.8 2.3 0.36 10.4 1.6 1.2 1 0 0 1 1 1 0 GAGA factor zf-CCHC_2 PF13696.1 CEP11267.1 - 0.077 12.5 0.5 0.2 11.1 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Allexi_40kDa PF05549.6 CEP11269.1 - 0.00069 19.0 3.2 0.00088 18.6 2.2 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein V_ATPase_I PF01496.14 CEP11269.1 - 0.0048 14.8 3.1 0.0062 14.4 2.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family UPF0137 PF03677.8 CEP11269.1 - 0.0085 15.6 0.5 0.0095 15.5 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0137) DUF2240 PF09999.4 CEP11269.1 - 0.036 13.4 0.4 0.061 12.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Exonuc_VII_L PF02601.10 CEP11269.1 - 0.04 13.1 2.1 0.052 12.7 1.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AIP3 PF03915.8 CEP11269.1 - 0.04 12.8 5.1 0.051 12.4 3.5 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Baculo_PEP_C PF04513.7 CEP11269.1 - 0.044 13.6 6.5 0.064 13.0 4.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YPEB PF14620.1 CEP11269.1 - 0.057 12.4 4.7 0.074 12.0 3.2 1.1 1 0 0 1 1 1 0 YpeB sporulation Halogen_Hydrol PF10112.4 CEP11269.1 - 0.084 12.2 2.5 0.19 11.1 1.7 1.6 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PhoU_div PF01865.11 CEP11269.1 - 0.1 11.7 2.2 0.13 11.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 Tmemb_cc2 PF10267.4 CEP11269.1 - 0.11 11.0 4.7 0.26 9.8 3.2 1.6 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein WASH-7_C PF14746.1 CEP11269.1 - 0.12 11.9 1.7 0.19 11.3 1.2 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Spc7 PF08317.6 CEP11269.1 - 0.13 10.8 7.2 0.17 10.4 5.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein XkdW PF09636.5 CEP11269.1 - 0.18 11.6 0.9 0.28 11.0 0.6 1.3 1 0 0 1 1 1 0 XkdW protein DASH_Dad3 PF08656.5 CEP11269.1 - 0.29 10.8 2.9 0.83 9.3 2.0 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad3 YlqD PF11068.3 CEP11269.1 - 0.42 10.6 8.1 0.61 10.1 5.6 1.2 1 0 0 1 1 1 0 YlqD protein DUF1664 PF07889.7 CEP11269.1 - 0.44 10.3 4.7 1.3 8.8 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 CEP11269.1 - 0.64 9.8 7.5 0.81 9.5 5.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 CEP11269.1 - 0.64 9.9 6.6 1.5 8.7 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Hemagglutinin PF00509.13 CEP11269.1 - 1.1 7.3 4.5 6 4.8 0.9 2.0 1 1 1 2 2 2 0 Haemagglutinin Fib_alpha PF08702.5 CEP11269.1 - 2.7 8.1 7.6 3.6 7.7 5.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Retrotrans_gag PF03732.12 CEP11272.1 - 0.00037 20.4 1.0 0.0011 18.9 0.7 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CEP11272.1 - 0.0011 18.8 1.1 0.0017 18.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 CEP11273.1 - 6.6e-09 36.1 0.0 4.4e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP11273.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CEP11273.1 - 0.026 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.5 CEP11273.1 - 0.043 13.3 0.2 0.088 12.3 0.1 1.5 2 0 0 2 2 2 0 Aspartyl protease DDE_3 PF13358.1 CEP11274.1 - 2.9e-27 95.1 0.0 5.1e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L23eN PF03939.8 CEP11274.1 - 3.5e-19 68.5 9.3 3.5e-19 68.5 6.5 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 CEP11274.1 - 7.7e-19 67.4 1.6 2.8e-18 65.6 1.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L23 HTH_33 PF13592.1 CEP11274.1 - 0.071 12.6 0.1 0.51 9.9 0.0 2.4 2 1 1 3 3 3 0 Winged helix-turn helix ASL_C PF08328.6 CEP11274.1 - 0.075 12.8 0.3 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal SRF-TF PF00319.13 CEP11274.1 - 0.16 11.2 1.3 0.37 10.0 0.2 2.2 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) RabGAP-TBC PF00566.13 CEP11275.1 - 5.2e-55 186.2 0.6 5.2e-55 186.2 0.4 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.4 CEP11275.1 - 0.0025 17.7 19.4 0.0046 16.8 13.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 CEP11275.1 - 0.1 12.5 9.5 0.39 10.5 2.2 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 CEP11275.1 - 0.31 10.0 15.5 0.57 9.1 10.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0242 PF06785.6 CEP11275.1 - 0.45 9.1 11.4 0.7 8.5 7.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF724 PF05266.9 CEP11275.1 - 4.8 6.7 15.3 0.25 10.9 5.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 CEP11275.1 - 5.9 6.4 24.5 11 5.5 7.6 2.5 1 1 1 2 2 2 0 IncA protein DNA_primase_lrg PF04104.9 CEP11276.1 - 2.2e-83 279.5 0.6 2.2e-83 279.5 0.4 1.9 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit NMT_C PF02799.10 CEP11276.1 - 0.00053 19.4 1.1 0.0014 18.0 0.8 1.7 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Curto_V2 PF07325.6 CEP11276.1 - 0.45 10.1 5.3 8.8 6.0 0.3 3.6 3 1 1 4 4 4 0 Curtovirus V2 protein ATG13 PF10033.4 CEP11278.1 - 7.2e-35 120.5 1.1 2.3e-34 118.8 0.3 2.1 1 1 1 2 2 2 1 Autophagy-related protein 13 SIS PF01380.17 CEP11279.1 - 2.4e-61 205.1 0.2 2.9e-32 111.0 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CEP11279.1 - 5.9e-28 97.6 0.2 1.8e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CEP11279.1 - 6.4e-19 68.2 0.0 1.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CEP11279.1 - 7.7e-15 54.7 0.0 1.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CEP11279.1 - 1.8e-07 30.1 0.0 3.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CEP11279.1 - 7.4e-05 22.4 0.0 0.00022 20.9 0.0 1.9 1 0 0 1 1 1 1 SIS domain DUF4218 PF13960.1 CEP11280.1 - 0.0095 15.3 1.1 0.071 12.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Astro_capsid PF03115.9 CEP11283.1 - 0.0016 16.8 5.0 0.0017 16.6 3.5 1.1 1 0 0 1 1 1 1 Astrovirus capsid protein precursor Ribosomal_S15 PF00312.17 CEP11283.1 - 0.13 12.0 1.5 0.62 9.8 0.0 2.4 2 1 0 2 2 2 0 Ribosomal protein S15 TOM13 PF08219.6 CEP11283.1 - 0.15 11.8 2.6 0.62 9.8 0.1 2.6 1 1 1 2 2 2 0 Outer membrane protein TOM13 DUF2457 PF10446.4 CEP11283.1 - 0.29 9.8 13.5 0.4 9.3 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mem_trans PF03547.13 CEP11283.1 - 0.34 9.1 3.1 0.36 9.0 2.2 1.2 1 0 0 1 1 1 0 Membrane transport protein NPFF PF15085.1 CEP11283.1 - 2.1 8.6 5.1 5 7.4 3.2 2.0 1 1 0 1 1 1 0 Neuropeptide FF RhoGAP PF00620.22 CEP11285.1 - 1.4e-47 161.1 1.3 2.5e-47 160.3 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 CEP11285.1 - 0.00016 21.8 0.0 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 1 PH domain DUF1708 PF08101.6 CEP11285.1 - 0.0058 15.5 0.0 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Rax2 PF12768.2 CEP11286.1 - 3.8e-52 177.2 18.1 7.3e-43 146.7 0.1 5.8 3 1 3 6 6 6 5 Cortical protein marker for cell polarity SH3_9 PF14604.1 CEP11286.1 - 7.8e-11 41.3 0.1 1.7e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP11286.1 - 4.8e-08 32.2 0.1 9.8e-08 31.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP11286.1 - 2.9e-07 29.8 0.0 7.4e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kelch_1 PF01344.20 CEP11286.1 - 0.0002 20.7 0.1 3.4 7.3 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 CEP11286.1 - 0.022 14.4 4.4 3.5 7.4 0.2 4.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP11286.1 - 0.21 11.4 2.0 1.2e+02 2.6 0.0 5.2 6 0 0 6 6 6 0 Kelch motif Kelch_6 PF13964.1 CEP11286.1 - 1.8 8.8 7.1 3.8 7.8 0.4 4.3 4 0 0 4 4 4 0 Kelch motif Brix PF04427.13 CEP11287.1 - 1.3e-37 129.3 0.1 1.8e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain GDA1_CD39 PF01150.12 CEP11288.1 - 2.7e-112 375.4 0.0 3.6e-112 375.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family EamA PF00892.15 CEP11289.1 - 1.6e-09 37.8 27.2 2.3e-06 27.6 3.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF914 PF06027.7 CEP11289.1 - 7.6e-07 28.2 10.1 1e-06 27.8 7.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 CEP11289.1 - 1.8e-05 24.8 26.8 2.9e-05 24.2 1.5 2.5 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 CEP11289.1 - 0.0043 16.7 4.1 0.0043 16.7 2.8 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CEP11289.1 - 4 6.2 14.8 8.2 5.2 10.3 1.6 1 1 0 1 1 1 0 UAA transporter family Spc97_Spc98 PF04130.8 CEP11290.1 - 5.5e-119 397.9 14.7 8.4e-119 397.3 10.2 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Ras PF00071.17 CEP11291.1 - 2.9e-51 173.0 0.3 1.1e-50 171.2 0.2 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CEP11291.1 - 1.5e-17 64.2 0.0 2.6e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP11291.1 - 2.6e-11 43.0 0.1 3.1e-11 42.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP11291.1 - 6.2e-05 22.5 0.0 0.0003 20.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP11291.1 - 8.3e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEP11291.1 - 0.0044 16.1 0.1 0.014 14.5 0.1 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 CEP11291.1 - 0.014 14.6 0.1 0.086 12.0 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP11291.1 - 0.016 15.3 0.0 0.056 13.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEP11291.1 - 0.069 13.1 0.1 0.21 11.5 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain S6PP_C PF08472.5 CEP11291.1 - 0.084 12.4 0.1 2.7 7.6 0.0 2.9 2 2 2 4 4 4 0 Sucrose-6-phosphate phosphohydrolase C-terminal AAA_14 PF13173.1 CEP11291.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NAD_binding_10 PF13460.1 CEP11292.1 - 1.8e-09 37.8 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEP11292.1 - 3.2e-06 26.5 0.0 4.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family UQ_con PF00179.21 CEP11293.1 - 1.6e-47 160.4 0.0 1.9e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEP11293.1 - 2.1e-05 24.2 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CEP11293.1 - 0.00023 21.0 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CEP11293.1 - 0.031 13.9 0.2 0.056 13.1 0.2 1.4 1 1 0 1 1 1 0 UEV domain WD40 PF00400.27 CEP11294.1 - 2e-19 68.6 0.2 6.1e-05 22.7 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Nup160 PF11715.3 CEP11294.1 - 0.00036 18.8 0.1 0.42 8.6 0.1 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CEP11294.1 - 0.066 12.6 0.1 3.7 6.9 0.0 2.6 2 1 0 3 3 3 0 PQQ-like domain ENTH PF01417.15 CEP11295.1 - 2.5e-46 156.5 0.1 4.4e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CEP11295.1 - 9e-06 24.5 0.0 2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 CEP11295.1 - 0.15 11.7 3.7 3.5 7.4 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif CBM_21 PF03370.8 CEP11296.1 - 1.7e-24 85.9 6.5 2.5e-24 85.4 3.4 2.0 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CEP11296.1 - 1.2e-06 28.4 1.5 2.7e-06 27.3 1.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) Cwf_Cwc_15 PF04889.7 CEP11296.1 - 0.58 9.8 4.9 11 5.6 0.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.6 CEP11297.1 - 3.8e-78 263.1 35.6 3.8e-78 263.1 24.7 1.3 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) HHH_8 PF14716.1 CEP11297.1 - 0.006 16.7 3.1 0.031 14.4 2.2 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain AKNA PF12443.3 CEP11297.1 - 0.72 9.8 10.9 1.5 8.8 3.8 3.5 2 1 0 2 2 2 0 AT-hook-containing transcription factor DUF1280 PF06918.9 CEP11297.1 - 3.6 6.7 14.7 1.1 8.3 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1280) Peptidase_S9 PF00326.16 CEP11301.1 - 1.9e-44 151.4 0.0 3e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEP11301.1 - 4.8e-11 42.6 0.0 7.5e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CEP11301.1 - 7.9e-08 31.8 0.0 1.8e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 CEP11301.1 - 2.1e-05 24.3 0.0 0.001 18.8 0.0 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 CEP11301.1 - 6.2e-05 22.6 0.2 0.00062 19.4 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 CEP11301.1 - 0.00031 19.3 0.3 0.007 14.8 0.2 2.5 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 CEP11301.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF829 PF05705.9 CEP11301.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S15 PF02129.13 CEP11301.1 - 0.0089 15.4 0.0 0.087 12.2 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 CEP11301.1 - 0.012 15.4 0.2 0.064 13.1 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP11301.1 - 0.02 14.4 0.0 0.086 12.3 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 CEP11301.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein LVIVD PF08309.6 CEP11301.1 - 0.15 11.0 0.8 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 LVIVD repeat Esterase_phd PF10503.4 CEP11301.1 - 0.18 11.0 0.0 1.3 8.1 0.0 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase HLH PF00010.21 CEP11302.1 - 5.8e-11 41.9 0.4 2.2e-10 40.0 0.3 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_7 PF02796.10 CEP11302.1 - 1.2e-06 28.2 0.6 2.1e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase DDE_3 PF13358.1 CEP11302.1 - 3.6e-05 23.5 0.0 0.0032 17.2 0.0 2.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP11302.1 - 0.00016 21.6 0.0 0.044 13.8 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.14 CEP11302.1 - 0.0014 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 CEP11302.1 - 0.0024 18.0 0.0 0.19 11.9 0.0 2.6 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 CEP11302.1 - 0.01 15.4 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.1 CEP11302.1 - 0.015 14.8 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MobC PF05713.6 CEP11302.1 - 0.015 15.2 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) HTH_24 PF13412.1 CEP11302.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.8 CEP11302.1 - 0.083 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Mor PF08765.6 CEP11302.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family HEAT_2 PF13646.1 CEP11303.1 - 3.7e-12 46.3 1.6 0.0018 18.5 0.0 5.5 3 3 3 6 6 6 3 HEAT repeats HEAT PF02985.17 CEP11303.1 - 8.8e-09 34.7 11.6 1.4 9.1 0.0 8.0 8 0 0 8 8 8 4 HEAT repeat Cohesin_HEAT PF12765.2 CEP11303.1 - 2e-06 27.5 0.6 15 5.6 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 CEP11303.1 - 0.009 15.8 0.1 9.4 6.2 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) V-ATPase_H_N PF03224.9 CEP11303.1 - 0.025 13.7 0.0 0.025 13.7 0.0 4.4 1 1 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.1 CEP11303.1 - 2.4 8.7 11.4 0.25 11.8 0.1 5.1 6 1 1 7 7 7 0 HEAT-like repeat Fork_head PF00250.13 CEP11304.1 - 3.5e-32 110.3 0.3 6.6e-32 109.4 0.2 1.4 1 0 0 1 1 1 1 Fork head domain 2OG-FeII_Oxy_3 PF13640.1 CEP11305.1 - 4.3e-13 49.6 0.1 7e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CEP11305.1 - 2.7e-09 36.5 0.0 4.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CEP11305.1 - 3.5e-05 24.0 0.1 5.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 CEP11305.1 - 0.025 13.3 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein AGTRAP PF06396.6 CEP11306.1 - 1.5e-08 34.4 0.0 1.7e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) GTP_EFTU PF00009.22 CEP11307.1 - 1.5e-57 194.0 0.0 4.1e-57 192.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEP11307.1 - 2.2e-33 114.3 0.1 7.4e-33 112.6 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEP11307.1 - 1.5e-16 60.2 2.7 2.1e-16 59.7 0.6 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF2011 PF09428.5 CEP11307.1 - 3.2e-07 30.2 2.9 1.1e-06 28.5 2.0 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) MMR_HSR1 PF01926.18 CEP11307.1 - 0.00037 20.4 0.3 0.0065 16.4 0.4 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CEP11307.1 - 0.0022 17.5 1.6 0.003 17.1 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Dynamin_N PF00350.18 CEP11307.1 - 0.052 13.3 0.9 22 4.8 0.1 3.4 3 0 0 3 3 3 0 Dynamin family HEAT_2 PF13646.1 CEP11308.1 - 6.4e-27 93.6 0.1 4e-14 52.6 0.0 3.9 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 CEP11308.1 - 6.6e-19 66.4 0.0 0.00014 21.9 0.0 6.1 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CEP11308.1 - 5.5e-09 36.2 0.1 0.031 14.7 0.0 4.6 3 1 2 5 5 5 3 HEAT-like repeat HEAT PF02985.17 CEP11308.1 - 0.00023 20.9 0.9 6.5 7.1 0.0 4.6 5 0 0 5 5 5 2 HEAT repeat DUF4451 PF14616.1 CEP11309.1 - 4.3e-20 71.7 2.7 7.5e-20 70.9 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) Acetyltransf_7 PF13508.1 CEP11309.1 - 0.0095 16.0 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.27 CEP11310.1 - 6.8e-60 196.9 19.0 5.4e-09 35.5 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP11310.1 - 1.7e-11 43.0 8.8 0.0083 14.3 0.0 5.4 1 1 4 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP11310.1 - 3e-10 39.6 2.1 6.1e-10 38.6 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP11310.1 - 3.6e-07 29.6 1.3 8.5e-07 28.4 0.9 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CEP11310.1 - 3.2e-06 26.7 0.0 0.0011 18.4 0.0 2.7 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 CEP11310.1 - 0.0012 17.7 5.4 0.063 12.0 0.9 4.0 1 1 2 4 4 4 2 Nup133 N terminal like PRANC PF09372.5 CEP11310.1 - 0.0021 18.0 1.1 0.0059 16.5 0.6 1.9 1 1 0 1 1 1 1 PRANC domain eIF2A PF08662.6 CEP11310.1 - 0.011 15.4 0.1 0.062 13.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A EPL1 PF10513.4 CEP11311.1 - 1.3e-31 109.9 3.8 1.3e-31 109.9 2.6 3.9 2 1 1 3 3 3 1 Enhancer of polycomb-like Glyco_hydro_18 PF00704.23 CEP11312.1 - 2.4e-22 79.8 4.1 4e-22 79.1 2.8 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 CEP11312.1 - 1.5e-14 53.4 23.4 1.5e-14 53.4 16.3 3.3 2 1 1 3 3 3 1 Carbohydrate binding domain (family 19) HNH_4 PF13395.1 CEP11313.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease DUF2072 PF09845.4 CEP11314.1 - 0.14 12.1 0.5 0.96 9.3 0.1 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DUF4098 PF13345.1 CEP11314.1 - 0.22 11.4 10.0 0.37 10.7 6.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4098) Sugar_tr PF00083.19 CEP11315.1 - 3.6e-112 375.2 23.6 5.4e-112 374.6 16.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP11315.1 - 4.7e-26 91.3 39.5 6.9e-22 77.6 12.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.26 CEP11316.1 - 9.4e-27 92.5 3.9 1.5e-26 91.8 2.7 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CEP11316.1 - 4.3e-23 81.0 0.7 4.9e-19 68.0 0.1 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain RPT PF13446.1 CEP11316.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Sad1_UNC PF07738.8 CEP11317.1 - 1.3e-34 118.9 0.2 3.1e-34 117.6 0.1 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal HCNGP PF07818.8 CEP11317.1 - 1.1e-24 86.3 2.1 2.3e-24 85.2 0.0 2.8 2 0 0 2 2 2 1 HCNGP-like protein Muskelin_N PF06588.6 CEP11317.1 - 0.0011 18.7 0.2 0.0027 17.4 0.1 1.6 1 0 0 1 1 1 1 Muskelin N-terminus DUF2142 PF09913.4 CEP11317.1 - 0.22 10.1 0.0 0.56 8.8 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) NAD_kinase PF01513.16 CEP11318.1 - 1.5e-56 191.3 0.0 1.9e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase LigB PF02900.13 CEP11318.1 - 0.062 12.2 0.1 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Ras PF00071.17 CEP11319.1 - 1.2e-67 226.3 0.1 1.5e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP11319.1 - 4.3e-21 75.6 0.1 1.2e-20 74.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP11319.1 - 3.4e-15 55.7 0.0 4.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP11319.1 - 3.2e-06 26.4 0.1 3.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP11319.1 - 3.4e-06 26.6 0.2 8.8e-06 25.2 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CEP11319.1 - 4.4e-05 22.7 0.1 5.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEP11319.1 - 0.00031 20.6 0.0 0.00046 20.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP11319.1 - 0.007 15.6 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_29 PF13555.1 CEP11319.1 - 0.035 13.6 0.1 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP11319.1 - 0.045 13.7 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 CEP11319.1 - 0.063 12.4 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 CEP11319.1 - 0.099 12.8 0.1 3.5 7.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP11319.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 CEP11319.1 - 0.22 10.1 2.1 13 4.3 0.1 3.0 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.22 CEP11319.1 - 0.54 10.5 2.3 2.8 8.2 1.6 2.1 1 1 0 1 1 1 0 ABC transporter Epimerase PF01370.16 CEP11320.1 - 1.3e-45 155.6 0.0 1.8e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEP11320.1 - 3.5e-13 48.9 0.0 4.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CEP11320.1 - 2.3e-12 46.4 0.0 3.1e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CEP11320.1 - 1e-10 40.9 0.1 2.1e-06 26.8 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 CEP11320.1 - 1.3e-08 34.1 0.1 1.4e-05 24.1 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CEP11320.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CEP11320.1 - 0.0086 16.0 0.0 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Cyt-b5 PF00173.23 CEP11321.1 - 1.3e-08 34.4 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Drf_GBD PF06371.8 CEP11322.1 - 1.4 8.2 4.4 5.7 6.2 0.0 2.8 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain FHA PF00498.21 CEP11323.1 - 3.8e-15 55.7 0.2 6.6e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CEP11323.1 - 1e-09 38.0 8.3 1.7e-09 37.3 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP11323.1 - 3.2e-05 23.9 6.6 8.3e-05 22.6 4.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP11323.1 - 6.7e-05 22.4 7.4 0.00013 21.5 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP11323.1 - 0.00084 19.0 6.9 0.0016 18.1 4.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP11323.1 - 0.00096 18.7 5.6 0.0016 18.0 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CEP11323.1 - 0.0041 16.7 3.4 0.0072 15.9 2.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 CEP11323.1 - 0.011 15.7 9.3 0.02 14.9 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEP11323.1 - 0.02 14.7 1.6 0.038 13.8 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mit_ribos_Mrp51 PF11709.3 CEP11324.1 - 6.2e-18 65.0 6.8 6.2e-14 51.9 2.9 3.7 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit RCC1 PF00415.13 CEP11325.1 - 5.1e-27 93.8 0.5 8.8e-09 35.4 0.1 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEP11325.1 - 2e-16 59.0 14.5 4.6e-09 35.6 1.6 4.9 4 1 1 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RWD PF05773.17 CEP11326.1 - 3.3e-21 75.2 4.7 5.8e-21 74.5 3.2 1.4 1 0 0 1 1 1 1 RWD domain DUF445 PF04286.7 CEP11326.1 - 0.013 15.0 3.4 0.016 14.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PK PF00224.16 CEP11327.1 - 9.4e-165 547.3 2.2 1.2e-164 547.0 1.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CEP11327.1 - 4.5e-24 84.2 0.1 1.2e-23 82.8 0.1 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CEP11327.1 - 1.9e-05 23.6 0.5 6.7e-05 21.8 0.1 1.8 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 CEP11327.1 - 0.0069 15.3 1.2 0.2 10.5 0.0 2.8 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.13 CEP11327.1 - 0.072 12.2 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) GTP_EFTU PF00009.22 CEP11328.1 - 9.9e-58 194.6 0.3 1.6e-57 193.9 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEP11328.1 - 1.1e-33 115.3 0.1 3.6e-33 113.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEP11328.1 - 1.2e-16 60.6 0.8 1.2e-16 60.6 0.6 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEP11328.1 - 0.00085 19.2 0.6 0.0028 17.5 0.4 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CEP11328.1 - 0.0015 18.0 1.9 0.0016 18.0 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 RasGEF PF00617.14 CEP11329.1 - 5.1e-57 192.6 0.2 1.6e-56 191.0 0.1 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEP11329.1 - 2.5e-17 62.8 0.5 1.9e-16 60.0 0.1 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 CEP11329.1 - 7.8e-09 34.7 0.1 2.6e-08 33.1 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CEP11329.1 - 2e-08 33.5 0.1 4e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CEP11329.1 - 3e-06 26.6 0.2 6.1e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain cwf21 PF08312.7 CEP11329.1 - 0.67 9.8 4.2 24 4.8 0.1 3.7 3 0 0 3 3 3 0 cwf21 domain Chitin_synth_1 PF01644.12 CEP11330.1 - 8.1e-82 272.8 0.0 1.3e-81 272.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CEP11330.1 - 1.3e-32 111.2 0.2 2.8e-32 110.2 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEP11330.1 - 1.1e-23 83.3 2.0 2.3e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP11330.1 - 1e-09 38.3 0.9 1e-09 38.3 0.6 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP11330.1 - 1.1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Abhydrolase_6 PF12697.2 CEP11331.1 - 2.2e-13 50.6 0.0 3.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP11331.1 - 2.7e-07 30.3 0.0 9.9e-07 28.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP11331.1 - 0.0014 18.4 0.0 0.0037 17.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CEP11331.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Arrestin_N PF00339.24 CEP11332.1 - 4.4e-11 42.8 0.0 1.2e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP11332.1 - 0.00017 21.7 0.3 0.00029 20.9 0.2 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Epimerase PF01370.16 CEP11333.1 - 3.8e-51 173.8 0.6 2.9e-50 170.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CEP11333.1 - 3.1e-18 65.6 0.7 4.4e-18 65.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 CEP11333.1 - 4.8e-17 61.7 0.0 7.4e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CEP11333.1 - 6.9e-15 54.7 0.2 1.7e-13 50.1 0.2 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CEP11333.1 - 2.2e-14 52.8 0.1 2.2e-14 52.8 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CEP11333.1 - 0.013 15.5 0.0 0.029 14.3 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding DUF619 PF04768.8 CEP11334.1 - 1.2e-41 141.9 0.2 3.5e-40 137.1 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF619) Sel1 PF08238.7 CEP11335.1 - 2.1e-16 59.9 21.0 2.5e-08 34.2 0.3 7.4 8 0 0 8 8 8 5 Sel1 repeat TPR_7 PF13176.1 CEP11335.1 - 0.36 10.7 3.0 5.8 6.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 CEP11336.1 - 8.4e-14 51.8 0.0 1.9e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP11336.1 - 1.9e-09 37.7 0.0 7.6e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP11336.1 - 6.5e-07 29.5 0.0 2.3e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 CEP11336.1 - 2.6e-06 26.6 0.1 3.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CEP11336.1 - 1.6e-05 24.5 0.0 4.9e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CEP11336.1 - 0.0016 18.0 0.3 0.0016 18.0 0.2 3.1 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CEP11336.1 - 0.0097 15.6 0.0 0.0097 15.6 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_30 PF13604.1 CEP11336.1 - 0.017 14.6 0.5 0.084 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Daxx PF03344.10 CEP11336.1 - 0.028 12.9 9.5 0.048 12.1 6.6 1.3 1 0 0 1 1 1 0 Daxx Family KaiC PF06745.8 CEP11336.1 - 0.05 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 CEP11336.1 - 0.055 13.3 0.0 0.22 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 CEP11336.1 - 0.11 11.7 0.2 0.11 11.7 0.1 2.4 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain Cdc6_C PF09079.6 CEP11336.1 - 0.13 11.9 1.4 0.35 10.6 0.0 2.5 3 0 0 3 3 3 0 CDC6, C terminal Peptidase_C12 PF01088.16 CEP11337.1 - 1.9e-60 203.6 0.1 4.1e-60 202.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Rota_NSP3 PF01665.11 CEP11337.1 - 0.017 14.1 1.1 0.024 13.5 0.8 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 KAT11 PF08214.6 CEP11339.1 - 4.1e-32 111.6 0.1 5.7e-32 111.1 0.1 1.2 1 0 0 1 1 1 1 Histone acetylation protein DUF2839 PF10999.3 CEP11342.1 - 0.3 11.1 3.2 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Rad1 PF02144.11 CEP11343.1 - 0.0042 15.8 0.1 0.018 13.8 0.1 1.8 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF4252 PF14060.1 CEP11343.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Lactamase_B PF00753.22 CEP11344.1 - 4.7e-17 62.2 0.8 1.5e-16 60.6 0.5 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Rhodanese PF00581.15 CEP11344.1 - 1.9e-15 57.1 0.0 4.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Lactamase_B_2 PF12706.2 CEP11344.1 - 0.00041 19.9 0.3 0.00099 18.7 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PCI PF01399.22 CEP11345.1 - 8.9e-19 67.7 2.0 3.7e-18 65.7 0.1 2.5 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CEP11345.1 - 0.0033 17.1 0.8 0.017 14.9 0.6 2.4 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 Exo_endo_phos PF03372.18 CEP11346.1 - 5.5e-19 69.0 0.0 8.9e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CEP11346.1 - 1.1e-17 63.2 9.5 4e-10 39.0 0.6 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP11346.1 - 8.1e-10 38.3 12.6 1.5e-06 27.8 3.6 2.8 1 1 3 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CEP11346.1 - 1.2e-07 30.7 8.4 0.02 14.8 0.1 5.3 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CEP11346.1 - 9.7e-06 24.9 9.1 0.24 11.7 0.2 4.9 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 CEP11346.1 - 0.37 10.9 8.1 12 6.3 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeat DFP PF04127.10 CEP11347.1 - 1.4e-19 70.4 0.0 7.2e-12 45.2 0.0 2.2 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein Zn_clus PF00172.13 CEP11348.1 - 4.6e-05 23.2 13.4 8.6e-05 22.3 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain POP1 PF06978.6 CEP11349.1 - 2e-44 151.5 14.3 4.8e-26 91.5 3.6 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CEP11349.1 - 6.8e-24 83.5 0.0 2e-23 82.0 0.0 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 CEP11349.1 - 5.7e-08 32.3 0.0 0.015 14.6 0.0 2.8 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain Glycos_transf_2 PF00535.21 CEP11350.1 - 1.6e-23 83.2 0.0 2e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CEP11350.1 - 1.3e-08 34.9 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CEP11350.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 MutL_C PF08676.6 CEP11351.1 - 2e-23 82.5 0.0 4.6e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CEP11351.1 - 2.3e-23 81.9 0.5 1.7e-21 75.8 0.3 2.8 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CEP11351.1 - 1.2e-13 50.9 0.0 1.2e-13 50.9 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CEP11351.1 - 2.5e-10 40.0 0.0 6.3e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fe_dep_repr_C PF02742.10 CEP11351.1 - 0.15 11.8 0.1 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Prenyltrans PF00432.16 CEP11352.1 - 3.2e-28 96.9 0.1 2.4e-06 26.9 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CEP11352.1 - 1.5e-17 64.0 0.0 2.8e-07 30.9 0.0 3.8 2 1 2 4 4 4 3 Prenyltransferase-like F-box-like PF12937.2 CEP11353.1 - 4.9e-08 32.5 2.5 4.9e-08 32.5 1.7 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CEP11353.1 - 4.1e-07 29.4 3.9 8.1e-07 28.5 1.5 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 CEP11353.1 - 2.8e-05 23.6 11.1 0.72 9.5 0.7 5.5 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CEP11353.1 - 0.00035 20.3 19.6 1.3 9.2 0.1 7.1 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.1 CEP11353.1 - 0.0077 15.9 18.0 0.025 14.3 0.6 5.7 5 1 2 7 7 7 1 Leucine rich repeat Apc3 PF12895.2 CEP11353.1 - 0.022 14.8 2.1 0.14 12.3 0.5 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_7 PF13504.1 CEP11353.1 - 0.058 13.6 12.4 66 4.4 0.4 7.0 8 0 0 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 CEP11353.1 - 0.17 12.0 10.1 18 5.8 0.0 6.1 4 1 0 4 4 4 0 Leucine Rich Repeat zf-C2H2 PF00096.21 CEP11354.1 - 0.011 15.9 8.2 0.064 13.6 0.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP11354.1 - 1.5 9.3 9.1 0.38 11.1 0.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-DHHC PF01529.15 CEP11355.1 - 0.0097 15.3 0.2 0.015 14.6 0.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Adeno_E3_CR2 PF02439.10 CEP11355.1 - 0.24 10.9 2.4 0.45 10.0 1.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SPK PF04435.13 CEP11356.1 - 6.8 6.7 7.5 3.5 7.6 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF545) DDE_3 PF13358.1 CEP11357.1 - 1.1e-20 73.9 0.0 1.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP11357.1 - 0.00078 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF4240 PF14024.1 CEP11357.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) DDE_Tnp_ISAZ013 PF07592.6 CEP11357.1 - 0.13 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain NB-ARC PF00931.17 CEP11357.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain DDE_3 PF13358.1 CEP11359.1 - 9.1e-25 87.1 0.0 2.2e-24 85.8 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP11359.1 - 0.0014 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 CEP11359.1 - 0.066 12.3 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF4240 PF14024.1 CEP11359.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Ion_trans PF00520.26 CEP11360.1 - 3.9e-114 378.8 72.0 4.5e-34 117.4 6.6 5.1 5 0 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 CEP11360.1 - 0.017 14.4 0.0 0.16 11.3 0.0 2.5 2 0 0 2 2 2 0 EF hand SSB PF00436.20 CEP11361.1 - 6.6e-12 45.2 0.0 7.4e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Single-strand binding protein family Bac_export_3 PF01313.14 CEP11362.1 - 0.0083 15.7 0.2 0.045 13.4 0.1 2.2 1 0 0 1 1 1 1 Bacterial export proteins, family 3 DUF373 PF04123.8 CEP11362.1 - 3.8 6.4 7.3 8.5 5.2 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Kinesin PF00225.18 CEP11363.1 - 5.8e-94 314.5 0.5 5.8e-94 314.5 0.4 2.3 2 0 0 2 2 2 1 Kinesin motor domain SAM_1 PF00536.25 CEP11363.1 - 0.012 15.7 0.1 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) WD40 PF00400.27 CEP11365.1 - 2.1e-56 185.8 15.0 7.7e-11 41.4 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CEP11365.1 - 9.4e-11 40.5 6.0 0.0078 14.4 0.0 5.1 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP11365.1 - 1.1e-10 41.0 0.3 1.1e-10 41.0 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP11365.1 - 2.4e-08 33.3 0.1 7.3e-08 31.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CEP11365.1 - 0.0015 18.0 0.5 0.055 12.9 0.3 2.5 1 1 1 2 2 2 2 PQQ-like domain CDtoxinA PF03498.9 CEP11365.1 - 0.11 11.8 0.7 0.33 10.3 0.1 2.1 2 0 0 2 2 2 0 Cytolethal distending toxin A/C family Retrotrans_gag PF03732.12 CEP11366.1 - 1.8e-06 27.9 0.3 1.8e-06 27.9 0.2 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF1473 PF07341.6 CEP11366.1 - 0.015 14.8 1.0 0.59 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1473) Ribosomal_S7 PF00177.16 CEP11367.1 - 2.6e-39 134.1 0.3 3.1e-39 133.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Oxysterol_BP PF01237.13 CEP11368.1 - 1.5e-90 303.2 0.8 1.8e-90 302.9 0.5 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Arrestin_C PF02752.17 CEP11368.1 - 0.049 13.7 0.1 0.094 12.8 0.1 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain NicO PF03824.11 CEP11369.1 - 3.5e-77 259.5 16.2 4.8e-77 259.0 11.2 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein BIV_Env PF05858.7 CEP11369.1 - 0.06 11.3 1.8 0.084 10.8 0.7 1.7 1 1 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) E1_DerP2_DerF2 PF02221.10 CEP11370.1 - 1.4e-12 47.9 0.1 1.7e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CEP11370.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 1 0 1 1 1 1 ML-like domain HLH PF00010.21 CEP11371.1 - 3.1e-14 52.3 0.5 3.1e-14 52.3 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3340 PF11818.3 CEP11371.1 - 0.11 12.4 8.0 0.27 11.2 5.5 1.7 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) FSH1 PF03959.8 CEP11372.1 - 1.2e-57 194.8 0.0 1.3e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CEP11372.1 - 8.9e-05 22.2 0.0 0.00014 21.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP11372.1 - 9e-05 22.4 0.0 0.015 15.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CEP11372.1 - 0.0066 15.9 0.1 2.4 7.5 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 CEP11372.1 - 0.032 13.7 0.2 0.14 11.7 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.15 CEP11372.1 - 0.069 12.5 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Thioesterase PF00975.15 CEP11372.1 - 0.11 12.7 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Abhydro_lipase PF04083.11 CEP11372.1 - 0.15 11.3 0.1 10 5.5 0.0 2.7 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region Nup35_RRM PF05172.8 CEP11373.1 - 2.6e-14 52.7 0.2 8.4e-14 51.1 0.2 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CEP11373.1 - 6.1e-08 32.3 0.0 9.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 CEP11373.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP11373.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beta_helix PF13229.1 CEP11373.1 - 0.41 10.3 3.5 1 9.1 2.2 1.7 1 1 0 1 1 1 0 Right handed beta helix region Mito_carr PF00153.22 CEP11374.1 - 7.5e-38 128.1 2.5 3.2e-13 49.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 CEP11375.1 - 1.4e-34 119.3 72.9 9e-30 103.5 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP11375.1 - 9.4e-14 50.6 11.8 9.4e-14 50.6 8.2 2.6 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 CEP11375.1 - 0.00057 19.6 0.3 0.00057 19.6 0.2 2.9 3 0 0 3 3 3 1 MFS_1 like family Sugar_tr PF00083.19 CEP11375.1 - 1.3 7.4 41.6 3.2 6.2 12.3 2.7 2 1 1 3 3 3 0 Sugar (and other) transporter GIT_SHD PF08518.6 CEP11376.1 - 1.5e-24 85.0 1.3 3.3e-12 45.5 0.4 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TPR_1 PF00515.23 CEP11376.1 - 3.9e-21 73.7 18.7 4.3e-05 22.9 1.3 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat APC8 PF04049.8 CEP11376.1 - 5e-20 71.6 2.3 9.3e-20 70.8 0.3 2.5 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.12 CEP11376.1 - 5.7e-19 66.4 18.1 0.00096 18.9 0.2 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 CEP11376.1 - 8.6e-18 63.7 21.3 3.1e-10 39.5 0.7 6.2 6 1 1 7 7 6 3 TPR repeat TPR_16 PF13432.1 CEP11376.1 - 2.3e-13 50.4 15.2 1.8e-10 41.2 0.3 6.9 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP11376.1 - 4.1e-12 45.8 20.6 2.6e-06 27.2 0.2 5.8 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP11376.1 - 2.8e-10 39.8 14.4 0.0089 16.5 0.3 8.4 6 1 4 10 10 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11376.1 - 2.4e-09 36.2 21.3 0.063 13.0 0.0 7.7 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEP11376.1 - 6.4e-09 35.3 5.5 0.0042 17.1 0.2 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP11376.1 - 3e-08 33.8 7.5 0.31 11.4 0.5 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEP11376.1 - 2.3e-06 26.9 14.1 0.021 14.5 0.2 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat ERM PF00769.14 CEP11376.1 - 0.00033 20.2 7.7 0.00033 20.2 5.3 2.5 3 1 0 3 3 2 1 Ezrin/radixin/moesin family Cep57_MT_bd PF06657.8 CEP11376.1 - 0.0024 17.8 3.0 0.012 15.5 2.1 2.2 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 DUF3410 PF11890.3 CEP11376.1 - 0.003 17.1 2.3 0.015 14.9 0.4 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3410) Apc3 PF12895.2 CEP11376.1 - 0.0031 17.5 3.1 0.0031 17.5 2.1 4.9 3 1 2 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3450 PF11932.3 CEP11376.1 - 0.015 14.6 11.8 0.067 12.4 8.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_9 PF13371.1 CEP11376.1 - 0.036 13.9 2.5 3.1 7.7 1.4 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP11376.1 - 0.062 13.7 23.4 12 6.6 0.0 7.8 9 0 0 9 9 6 0 Tetratricopeptide repeat APG6 PF04111.7 CEP11376.1 - 0.09 11.8 19.1 0.0052 15.8 8.7 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 TPR_10 PF13374.1 CEP11376.1 - 0.11 12.5 5.3 4.4 7.3 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Tropomyosin PF00261.15 CEP11376.1 - 0.15 11.1 19.4 0.01 14.9 9.7 1.8 2 0 0 2 2 1 0 Tropomyosin BTAD PF03704.12 CEP11376.1 - 0.63 10.3 8.1 2.1 8.6 0.3 3.8 4 0 0 4 4 2 0 Bacterial transcriptional activator domain bZIP_1 PF00170.16 CEP11376.1 - 0.7 9.8 9.5 1.3 9.0 3.1 3.2 1 1 1 2 2 2 0 bZIP transcription factor Sel1 PF08238.7 CEP11376.1 - 2 9.1 10.1 9.7 6.9 1.4 4.5 4 0 0 4 4 4 0 Sel1 repeat Syntaxin PF00804.20 CEP11376.1 - 3.3 7.9 15.6 32 4.7 2.1 3.7 1 1 1 2 2 2 0 Syntaxin DivIC PF04977.10 CEP11376.1 - 5.2 6.6 16.9 5.4 6.5 5.0 3.6 2 1 1 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.3 CEP11376.1 - 5.8 6.7 19.1 0.024 14.4 4.0 3.2 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding Sugar_tr PF00083.19 CEP11377.1 - 1.3e-95 320.6 37.5 1.1e-49 169.2 15.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP11377.1 - 4.2e-23 81.6 45.5 2.5e-20 72.4 15.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Poxvirus_B22R_N PF13169.1 CEP11378.1 - 0.0014 18.7 2.2 0.0021 18.2 1.5 1.3 1 0 0 1 1 1 1 Poxvirus B22R protein N-terminal Queuosine_synth PF02547.10 CEP11378.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein LRR_4 PF12799.2 CEP11380.1 - 2.7e-42 141.7 59.2 1.4e-06 27.8 0.8 11.7 7 3 4 13 13 13 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP11380.1 - 7.2e-31 105.7 49.3 1e-08 34.7 1.2 10.0 5 2 8 13 13 13 10 Leucine rich repeat LRR_1 PF00560.28 CEP11380.1 - 4.1e-25 83.9 39.6 0.17 12.0 0.2 17.4 19 0 0 19 19 19 8 Leucine Rich Repeat LRR_7 PF13504.1 CEP11380.1 - 7.4e-15 52.4 42.4 1.2 9.6 0.5 15.7 17 0 0 17 17 17 5 Leucine rich repeat LRR_6 PF13516.1 CEP11380.1 - 1.9e-10 39.6 50.4 0.1 12.7 0.1 12.9 12 3 2 14 14 14 6 Leucine Rich repeat LRR_9 PF14580.1 CEP11380.1 - 5.2e-08 32.6 12.0 0.037 13.5 0.1 6.0 2 2 4 6 6 6 4 Leucine-rich repeat PRTP PF01366.13 CEP11380.1 - 0.095 10.6 2.8 0.14 10.0 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus processing and transport protein DPPIV_N PF00930.16 CEP11381.1 - 8.5e-99 330.4 6.1 8.5e-99 330.4 4.2 1.5 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CEP11381.1 - 5.1e-53 179.4 2.6 9e-53 178.6 1.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEP11381.1 - 1.9e-11 43.8 0.1 5.1e-11 42.5 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP11381.1 - 1.5e-07 31.5 0.5 2.9e-06 27.3 0.4 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CEP11381.1 - 2e-05 24.1 4.1 3.6e-05 23.3 1.1 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 CEP11381.1 - 0.0006 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 CEP11381.1 - 0.0014 18.1 0.3 0.097 12.1 0.1 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CEP11381.1 - 0.0016 18.2 0.1 0.018 14.7 0.1 2.3 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CEP11381.1 - 0.0082 15.4 0.4 0.081 12.1 0.3 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.9 CEP11381.1 - 0.063 12.4 0.9 0.14 11.3 0.6 1.5 1 0 0 1 1 1 0 Secretory lipase Alba PF01918.16 CEP11382.1 - 0.0086 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Alba Peptidase_S49_N PF08496.5 CEP11382.1 - 0.82 9.4 4.2 0.42 10.4 1.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal ERG4_ERG24 PF01222.12 CEP11383.1 - 1.2e-147 491.9 11.9 1.4e-147 491.7 8.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CEP11383.1 - 0.0027 17.0 0.6 0.0027 17.0 0.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) ATP-synt_J PF04911.7 CEP11383.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 ATP synthase j chain Septin PF00735.13 CEP11384.1 - 1.7e-111 371.8 0.0 1.7e-111 371.8 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CEP11384.1 - 7e-06 25.9 0.0 1.8e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEP11384.1 - 0.00074 19.3 3.2 0.66 9.7 0.0 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CEP11384.1 - 0.0076 15.4 0.2 0.035 13.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CEP11384.1 - 0.024 13.7 0.0 0.069 12.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.22 CEP11384.1 - 0.031 13.7 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 CEP11384.1 - 0.032 14.7 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 CEP11384.1 - 0.033 13.7 0.0 0.099 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CEP11384.1 - 0.069 13.2 0.3 0.32 11.1 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CEP11384.1 - 0.092 13.5 3.1 0.44 11.3 2.1 2.5 1 1 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.4 CEP11386.1 - 8.7e-07 28.6 0.7 2e-06 27.3 0.5 1.8 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase bZIP_1 PF00170.16 CEP11387.1 - 1.5e-12 47.2 8.9 1.5e-12 47.2 6.2 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP11387.1 - 8e-08 31.9 7.5 2.1e-07 30.6 5.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 CEP11387.1 - 6.9e-05 23.3 0.9 6.9e-05 23.3 0.6 3.0 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain HALZ PF02183.13 CEP11387.1 - 0.00059 19.4 0.9 0.0012 18.4 0.6 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_Maf PF03131.12 CEP11387.1 - 0.0034 17.6 3.9 0.0034 17.6 2.7 2.2 2 1 1 3 3 3 1 bZIP Maf transcription factor DUF2576 PF10845.3 CEP11387.1 - 0.051 12.7 0.1 0.12 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Phlebovirus_NSM PF07246.6 CEP11387.1 - 0.18 10.9 4.8 0.22 10.6 2.8 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF972 PF06156.8 CEP11387.1 - 0.76 10.1 6.3 0.32 11.3 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) 2-oxoacid_dh PF00198.18 CEP11388.1 - 8.7e-82 273.8 0.4 1.2e-81 273.3 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CEP11388.1 - 2.8e-18 65.3 2.0 6e-18 64.2 1.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 CEP11388.1 - 4.4e-05 23.1 0.6 0.00011 21.8 0.4 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_2 PF12700.2 CEP11388.1 - 0.00032 19.9 0.6 0.0028 16.8 0.1 2.1 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CEP11388.1 - 0.001 18.7 2.9 0.021 14.5 0.2 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like DUF2118 PF09891.4 CEP11388.1 - 0.012 15.3 0.1 0.029 14.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) DUF3614 PF12267.3 CEP11388.1 - 0.012 15.8 0.8 0.21 11.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) RnfC_N PF13375.1 CEP11388.1 - 0.015 15.0 0.2 0.037 13.7 0.2 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 CEP11388.1 - 0.021 15.1 0.8 4.3 7.7 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein DUF1473 PF07341.6 CEP11388.1 - 0.042 13.4 0.1 0.15 11.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1473) WD40 PF00400.27 CEP11389.1 - 5.3e-08 32.4 6.6 0.95 9.4 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat 4HBT PF03061.17 CEP11389.1 - 9.3e-08 32.0 0.0 2.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily NAPRTase PF04095.11 CEP11390.1 - 5e-64 215.9 0.7 5e-64 215.9 0.5 1.5 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) family PHP PF02811.14 CEP11390.1 - 0.043 13.5 1.0 0.65 9.7 0.0 2.7 2 1 0 2 2 2 0 PHP domain Zds_C PF08632.5 CEP11391.1 - 1.2e-14 53.4 0.3 2.8e-14 52.2 0.2 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term VIT1 PF01988.14 CEP11391.1 - 0.35 10.3 0.3 0.79 9.1 0.2 1.5 1 0 0 1 1 1 0 VIT family Septin PF00735.13 CEP11392.1 - 1.1e-114 382.2 0.6 1.4e-114 381.9 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEP11392.1 - 5.9e-08 32.6 0.0 1e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP11392.1 - 1.2e-07 31.0 0.1 2.1e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CEP11392.1 - 1.4e-06 27.5 0.0 2.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 CEP11392.1 - 1.1e-05 24.9 0.3 0.00029 20.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP11392.1 - 4.8e-05 22.6 0.1 0.00094 18.3 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 CEP11392.1 - 0.00013 21.7 1.5 0.26 11.1 0.5 2.7 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 CEP11392.1 - 0.00034 20.1 0.2 0.00041 19.8 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 CEP11392.1 - 0.00047 19.1 0.1 0.00088 18.2 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 CEP11392.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 CEP11392.1 - 0.0014 19.0 0.0 0.0035 17.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CEP11392.1 - 0.002 17.5 0.1 0.0066 15.8 0.0 1.9 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.1 CEP11392.1 - 0.0024 18.0 0.0 0.0048 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CEP11392.1 - 0.0031 17.0 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CEP11392.1 - 0.0042 17.0 0.1 0.009 16.0 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.1 CEP11392.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 CEP11392.1 - 0.015 16.1 0.8 1.1 10.0 0.1 2.6 1 1 1 2 2 2 0 AAA domain T2SE PF00437.15 CEP11392.1 - 0.026 13.4 0.2 0.052 12.4 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.8 CEP11392.1 - 0.027 13.3 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CEP11392.1 - 0.035 14.0 0.1 0.12 12.2 0.0 2.0 2 1 0 2 2 1 0 AAA domain IIGP PF05049.8 CEP11392.1 - 0.048 12.4 0.4 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.21 CEP11392.1 - 0.048 13.1 0.1 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 CEP11392.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain GBP PF02263.14 CEP11392.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain MobB PF03205.9 CEP11392.1 - 0.096 12.3 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 CEP11392.1 - 0.6 8.7 4.3 0.42 9.2 1.2 2.2 2 1 0 2 2 2 0 G-protein alpha subunit MULE PF10551.4 CEP11393.1 - 0.076 13.1 0.2 0.23 11.6 0.1 1.9 2 0 0 2 2 2 0 MULE transposase domain zf-H2C2_2 PF13465.1 CEP11395.1 - 7.6e-22 76.4 38.3 4.5e-08 33.0 0.7 5.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 CEP11395.1 - 5.3e-16 57.9 42.7 1.3e-05 25.2 0.5 5.7 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP11395.1 - 1.6e-09 37.4 35.1 0.0035 17.5 1.2 5.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP11395.1 - 6.7e-06 26.0 5.5 0.28 11.3 0.1 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEP11395.1 - 0.00074 19.3 15.5 0.55 10.2 0.1 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-TRAF PF02176.13 CEP11395.1 - 0.0017 18.6 9.4 0.38 11.1 1.3 3.6 1 1 2 3 3 3 3 TRAF-type zinc finger zf-met PF12874.2 CEP11395.1 - 0.011 15.8 6.3 0.42 10.8 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Herpes_DNAp_acc PF04929.7 CEP11395.1 - 0.059 12.3 2.8 0.1 11.5 2.0 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.11 CEP11395.1 - 0.71 9.7 5.3 1.1 9.0 1.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2064 PF09837.4 CEP11396.1 - 0.13 11.8 10.4 0.2 11.2 0.1 3.7 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2064) UVR PF02151.14 CEP11396.1 - 0.62 9.6 0.0 0.62 9.6 0.0 6.0 6 0 0 6 6 6 0 UvrB/uvrC motif Pox_A_type_inc PF04508.7 CEP11396.1 - 1.8 8.5 11.5 3.1 7.8 0.7 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat HTH_23 PF13384.1 CEP11397.1 - 7e-05 22.3 0.0 7e-05 22.3 0.0 2.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.1 CEP11397.1 - 0.00017 21.0 0.0 0.028 13.9 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix DDE_3 PF13358.1 CEP11397.1 - 0.00028 20.6 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP11397.1 - 0.00059 20.5 0.5 0.8 10.5 0.1 2.6 1 1 1 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.1 CEP11397.1 - 0.00075 18.9 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP11397.1 - 0.0012 18.9 0.1 0.058 13.5 0.0 2.9 1 1 2 3 3 3 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 CEP11397.1 - 0.0015 17.6 0.3 0.0037 16.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 PAX PF00292.13 CEP11397.1 - 0.0021 17.7 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_Crp_2 PF13545.1 CEP11397.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_28 PF13518.1 CEP11397.1 - 0.014 15.3 0.2 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.8 CEP11397.1 - 0.058 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TrmB PF01978.14 CEP11397.1 - 0.079 12.6 0.1 0.22 11.2 0.1 1.7 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB KAAG1 PF15354.1 CEP11398.1 - 0.11 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Kidney-associated antigen 1 SR-25 PF10500.4 CEP11399.1 - 6.1 6.2 11.3 8.3 5.8 7.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 CEP11400.1 - 1.7e-07 30.8 4.4 3.1e-07 29.9 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 CEP11400.1 - 1.9e-05 25.0 0.1 4.1e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP11400.1 - 7.1e-05 22.5 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_4 PF14392.1 CEP11400.1 - 0.012 15.2 1.6 0.012 15.2 1.1 1.8 2 0 0 2 2 2 0 Zinc knuckle Auxin_resp PF06507.8 CEP11400.1 - 0.023 14.5 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 Auxin response factor RVP PF00077.15 CEP11400.1 - 0.04 13.8 0.2 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease HrpB2 PF09487.5 CEP11400.1 - 0.057 13.6 0.3 0.087 13.0 0.2 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) zf-CCHC_5 PF14787.1 CEP11400.1 - 3.9 7.0 7.7 6.7 6.2 5.3 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger VRR_NUC PF08774.6 CEP11401.1 - 0.052 13.5 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 VRR-NUC domain zf-3CxxC PF13695.1 CEP11402.1 - 0.042 14.0 1.7 0.059 13.5 0.4 1.7 1 1 1 2 2 2 0 Zinc-binding domain GDE_N PF12439.3 CEP11402.1 - 0.07 12.3 1.1 0.081 12.1 0.8 1.0 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal DUF2570 PF10828.3 CEP11402.1 - 0.16 11.5 4.9 0.2 11.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Ashwin PF15323.1 CEP11402.1 - 0.59 10.0 10.6 0.68 9.8 7.3 1.1 1 0 0 1 1 1 0 Developmental protein Baculo_p47 PF05112.7 CEP11402.1 - 0.61 9.4 6.9 1.1 8.5 4.8 1.5 1 1 0 1 1 1 0 Baculovirus P47 protein GcrA PF07750.6 CEP11402.1 - 0.99 9.5 4.2 1.3 9.2 2.9 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator Phosphoesterase PF04185.9 CEP11404.1 - 5e-31 108.2 10.2 4.2e-28 98.6 1.6 3.0 2 1 1 3 3 3 3 Phosphoesterase family Glyco_transf_49 PF13896.1 CEP11405.1 - 1.1e-39 136.3 0.4 2.4e-33 115.6 0.1 2.9 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CEP11405.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 IlvN PF07991.7 CEP11406.1 - 1.5e-45 154.5 0.0 4.2e-45 153.0 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 CEP11406.1 - 4e-45 153.3 0.0 7e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 CEP11406.1 - 0.0014 19.0 0.1 0.015 15.6 0.0 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CEP11406.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CEP11406.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aldolase_II PF00596.16 CEP11407.1 - 1.1e-45 155.5 0.0 1.5e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TPR_11 PF13414.1 CEP11408.1 - 2e-53 177.9 37.9 9e-11 41.2 0.1 13.3 8 4 7 16 16 16 12 TPR repeat TPR_2 PF07719.12 CEP11408.1 - 6.2e-45 147.5 42.3 0.00038 20.1 0.0 18.4 19 0 0 19 19 19 11 Tetratricopeptide repeat TPR_1 PF00515.23 CEP11408.1 - 7e-45 148.8 33.8 4.7e-06 25.9 0.1 16.6 17 0 0 17 17 16 9 Tetratricopeptide repeat TPR_12 PF13424.1 CEP11408.1 - 3.6e-34 116.5 33.6 6.8e-08 32.3 0.1 14.1 9 2 6 15 15 15 11 Tetratricopeptide repeat TPR_14 PF13428.1 CEP11408.1 - 2.3e-31 105.3 15.7 0.0019 18.6 0.0 16.4 13 3 5 18 18 15 6 Tetratricopeptide repeat TPR_16 PF13432.1 CEP11408.1 - 7.4e-31 106.1 20.7 9.8e-05 22.9 0.2 12.9 11 2 6 17 17 15 8 Tetratricopeptide repeat TPR_17 PF13431.1 CEP11408.1 - 1.5e-29 99.6 32.9 0.017 15.2 0.0 18.4 18 0 0 18 18 17 7 Tetratricopeptide repeat TPR_19 PF14559.1 CEP11408.1 - 8.4e-28 96.5 23.1 5.2e-05 23.4 0.0 13.1 10 3 2 13 13 13 5 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11408.1 - 5.2e-23 79.0 44.0 6.9e-06 25.4 0.0 15.0 17 1 1 18 18 17 5 Tetratricopeptide repeat TPR_7 PF13176.1 CEP11408.1 - 1.9e-17 61.5 13.4 0.022 14.5 0.0 11.1 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 CEP11408.1 - 3.4e-10 39.6 6.4 0.34 10.8 0.1 8.9 9 2 1 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 CEP11408.1 - 0.00011 22.4 34.1 1.2 9.7 0.0 13.1 16 0 0 16 16 14 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP11408.1 - 0.00036 20.3 18.1 2.5 8.1 0.3 9.7 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_4 PF07721.9 CEP11408.1 - 0.0026 18.0 5.8 17 6.2 0.3 6.2 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 CEP11408.1 - 0.075 13.1 3.4 8 6.6 0.0 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat Thioredoxin PF00085.15 CEP11409.1 - 5.4e-20 71.0 0.0 7.5e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CEP11409.1 - 9.5e-05 22.5 0.0 0.00041 20.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CEP11409.1 - 0.00065 19.6 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CEP11409.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like TrbC_Ftype PF09673.5 CEP11409.1 - 0.028 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein HTH_29 PF13551.1 CEP11410.1 - 8.5e-07 29.1 0.0 4.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CEP11410.1 - 0.0089 16.0 0.5 0.24 11.4 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain MarR_2 PF12802.2 CEP11410.1 - 0.058 13.0 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_36 PF13730.1 CEP11410.1 - 0.09 12.9 0.1 53 4.0 0.0 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain Radical_SAM PF04055.16 CEP11411.1 - 1.5e-16 61.0 0.0 3.4e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CEP11411.1 - 1.4e-10 41.0 0.0 3.8e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CEP11411.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein TFR_dimer PF04253.10 CEP11414.1 - 1.5e-21 76.2 0.0 2.7e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CEP11414.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 PA domain NAD_binding_1 PF00175.16 CEP11415.1 - 9.7e-30 103.3 0.0 8.1e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEP11415.1 - 4.7e-20 71.5 0.1 1.4e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CEP11415.1 - 1e-07 32.0 0.0 3.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CEP11415.1 - 0.0041 17.0 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain TFR_dimer PF04253.10 CEP11416.1 - 9.9e-22 76.8 0.0 2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 CEP11416.1 - 6.4e-16 58.6 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CEP11416.1 - 0.00035 20.1 0.0 0.00068 19.2 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CEP11416.1 - 0.046 13.2 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF4164 PF13747.1 CEP11416.1 - 0.77 9.9 3.6 0.38 10.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Y_phosphatase PF00102.22 CEP11418.1 - 5.3e-63 212.4 0.6 1.1e-62 211.4 0.4 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CEP11418.1 - 1e-09 38.7 0.0 6.1e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 CEP11418.1 - 0.0052 17.0 0.1 0.061 13.5 0.1 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CEP11418.1 - 0.28 11.2 1.8 1.8 8.5 0.3 2.8 2 1 0 3 3 3 0 Inositol hexakisphosphate Whi5 PF08528.6 CEP11419.1 - 0.015 14.9 0.1 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Whi5 like Npa1 PF11707.3 CEP11420.1 - 1.5e-73 247.6 0.9 3.2e-72 243.3 0.0 2.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 CEP11420.1 - 0.0069 16.5 0.0 0.047 13.8 0.0 2.4 1 0 0 1 1 1 1 Creb binding zf-C2H2 PF00096.21 CEP11422.1 - 0.0018 18.4 4.4 0.0018 18.4 3.0 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP11422.1 - 0.02 15.1 4.2 0.065 13.5 2.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DHHC PF01529.15 CEP11424.1 - 0.015 14.7 0.5 0.034 13.5 0.3 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF4469 PF14734.1 CEP11425.1 - 0.00087 19.1 0.0 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4469) with IG-like fold Arrestin_C PF02752.17 CEP11425.1 - 0.003 17.6 0.1 0.024 14.7 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain CRAL_TRIO PF00650.15 CEP11426.1 - 1.1e-39 135.4 0.1 2.4e-39 134.3 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CEP11426.1 - 3.9e-10 39.8 0.0 7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP11426.1 - 1.6e-09 37.7 0.1 3.5e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DDE_Tnp_1_7 PF13843.1 CEP11427.1 - 2.9e-34 118.6 0.1 1.3e-31 110.0 0.0 2.9 1 1 1 2 2 2 2 Transposase IS4 UPF0029 PF01205.14 CEP11427.1 - 0.031 13.9 0.1 0.42 10.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 OPT PF03169.10 CEP11428.1 - 1.3e-91 307.9 39.6 1.5e-91 307.7 27.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 CEP11428.1 - 0.00087 19.1 0.1 0.0032 17.2 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3093) RseC_MucC PF04246.7 CEP11428.1 - 0.59 9.7 10.4 0.25 10.9 0.4 3.4 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DDRGK PF09756.4 CEP11429.1 - 0.0018 17.6 10.7 0.0018 17.6 7.4 1.6 2 0 0 2 2 2 1 DDRGK domain OrfB_Zn_ribbon PF07282.6 CEP11429.1 - 0.0084 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Phyto_Pns9_10 PF05878.6 CEP11429.1 - 0.21 10.5 2.4 0.36 9.7 1.7 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 CDC45 PF02724.9 CEP11429.1 - 1.1 7.1 10.1 1.8 6.5 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1764 PF08576.5 CEP11429.1 - 1.9 9.3 11.7 4.9 7.9 8.1 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Saccharop_dh PF03435.13 CEP11430.1 - 1.1e-22 80.5 0.0 4.6e-22 78.5 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CEP11430.1 - 0.00022 21.3 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 2 NADH(P)-binding Cpn60_TCP1 PF00118.19 CEP11431.1 - 1.2e-158 528.6 3.1 1.6e-158 528.3 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pept_tRNA_hydro PF01195.14 CEP11432.1 - 2.8e-49 167.0 0.1 3.5e-49 166.7 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase L1R_F9L PF02442.12 CEP11432.1 - 0.037 13.5 0.1 0.05 13.0 0.1 1.1 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses NRDE-2 PF08424.5 CEP11433.1 - 1e-91 307.1 3.8 1e-91 307.1 2.6 4.0 4 1 0 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 CEP11433.1 - 1.1e-06 28.7 0.1 26 5.7 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP11433.1 - 1.7e-05 24.6 0.2 1.7e-05 24.6 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP11433.1 - 0.0034 17.1 1.2 1.8 8.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEP11433.1 - 0.0037 17.5 0.4 13 6.1 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat HMGL-like PF00682.14 CEP11434.1 - 9.5e-56 189.0 0.0 1.4e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like MCM PF00493.18 CEP11434.1 - 0.0059 15.4 0.5 0.0089 14.8 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family DUF3145 PF11343.3 CEP11434.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Transposase_21 PF02992.9 CEP11435.1 - 0.0037 16.3 0.0 0.0042 16.2 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Flagellin_IN PF07196.8 CEP11435.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif Ssu72 PF04722.8 CEP11436.1 - 9.3e-85 282.8 0.0 1e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PITH PF06201.8 CEP11437.1 - 1.2e-40 138.8 7.3 1.7e-40 138.2 5.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 CEP11437.1 - 5e-30 103.2 0.6 1.3e-29 101.9 0.4 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CEP11437.1 - 9.3e-06 25.8 0.2 0.00016 21.8 0.2 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEP11437.1 - 3.6e-05 23.7 0.6 0.00011 22.2 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 CEP11437.1 - 0.0016 17.9 0.1 0.0042 16.6 0.1 1.8 1 0 0 1 1 1 1 Redoxin Phosducin PF02114.11 CEP11437.1 - 0.054 12.2 0.0 0.093 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosducin Thioredoxin_7 PF13899.1 CEP11437.1 - 0.085 12.8 1.1 0.21 11.6 0.1 2.1 2 1 0 2 2 2 0 Thioredoxin-like UbiA PF01040.13 CEP11438.1 - 2.2e-24 86.0 19.2 2.8e-24 85.7 13.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family SNARE_assoc PF09335.6 CEP11438.1 - 0.56 10.4 7.5 1.1 9.4 3.7 2.4 1 1 1 2 2 2 0 SNARE associated Golgi protein Pkinase PF00069.20 CEP11439.1 - 1.9e-70 236.9 0.0 2.4e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11439.1 - 4.3e-34 117.7 0.0 5.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CEP11439.1 - 4.4e-05 22.9 0.1 0.00012 21.5 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 CEP11439.1 - 5.3e-05 22.3 0.0 6.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP11439.1 - 9.8e-05 21.5 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP11439.1 - 0.0038 16.9 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family G-alpha PF00503.15 CEP11440.1 - 8.7e-117 390.0 8.1 8.7e-117 390.0 5.6 1.5 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.16 CEP11440.1 - 2.1e-15 56.4 0.4 1.2e-10 40.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Rhodanese PF00581.15 CEP11440.1 - 4.8e-11 42.9 0.0 1.9e-10 41.0 0.0 2.0 1 1 1 2 2 2 1 Rhodanese-like domain Miro PF08477.8 CEP11440.1 - 0.00017 22.0 0.0 1.1 9.8 0.0 3.6 4 0 0 4 4 4 2 Miro-like protein Gtr1_RagA PF04670.7 CEP11440.1 - 0.0019 17.3 1.8 1.3 8.1 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CEP11440.1 - 0.061 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CEP11440.1 - 0.1 11.9 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP11440.1 - 0.25 11.3 2.1 3.5 7.6 0.2 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase Ribosomal_L37e PF01907.14 CEP11441.1 - 3.3e-26 90.8 13.2 6.1e-26 89.9 9.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 CEP11441.1 - 0.00028 20.6 3.8 0.00048 19.8 2.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CEP11441.1 - 0.0055 16.3 1.0 0.01 15.4 0.7 1.5 1 1 0 1 1 1 1 SelR domain zf-RING_5 PF14634.1 CEP11441.1 - 0.047 13.4 4.0 0.073 12.8 2.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.14 CEP11441.1 - 0.069 12.8 1.3 0.1 12.2 0.9 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family C1_1 PF00130.17 CEP11441.1 - 0.074 12.7 3.7 0.12 12.1 2.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MFP2b PF12150.3 CEP11441.1 - 0.092 11.4 0.1 0.1 11.2 0.1 1.0 1 0 0 1 1 1 0 Cytosolic motility protein Ogr_Delta PF04606.7 CEP11441.1 - 0.16 11.6 3.7 0.42 10.3 0.3 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zinc_ribbon_2 PF13240.1 CEP11441.1 - 0.34 10.4 4.8 6.3 6.4 3.6 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CEP11441.1 - 0.42 9.8 3.8 2.1 7.6 2.8 1.9 1 1 2 3 3 3 0 zinc-ribbon domain GFA PF04828.9 CEP11441.1 - 0.48 10.3 5.4 0.57 10.1 0.5 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_2 PF13923.1 CEP11441.1 - 0.63 10.1 4.9 1 9.4 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP11441.1 - 0.73 9.5 5.0 1.2 8.8 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 CEP11441.1 - 1.4 8.3 7.0 7.3 6.0 0.2 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e RNA_POL_M_15KD PF02150.11 CEP11441.1 - 3.2 7.5 5.6 22 4.8 3.9 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit YhfH PF14149.1 CEP11441.1 - 5.4 6.8 6.7 3.6 7.4 1.4 2.2 1 1 1 2 2 2 0 YhfH-like protein zf-HYPF PF07503.7 CEP11441.1 - 5.6 6.4 6.7 6.1 6.3 3.1 2.1 2 1 1 3 3 3 0 HypF finger PMT PF02366.13 CEP11442.1 - 3.5e-70 236.1 13.1 5.2e-70 235.5 9.1 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEP11442.1 - 5.1e-32 110.9 2.7 5.1e-32 110.9 1.9 2.3 3 0 0 3 3 3 1 MIR domain Methyltransf_31 PF13847.1 CEP11443.1 - 1.5e-12 47.4 0.5 5e-12 45.6 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP11443.1 - 2e-11 43.8 0.0 3.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP11443.1 - 2e-09 37.7 0.0 1e-08 35.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP11443.1 - 5.5e-09 36.5 0.0 1.2e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP11443.1 - 1.9e-07 31.4 0.2 2.3e-06 27.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 CEP11443.1 - 6.3e-07 28.9 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 CEP11443.1 - 2.9e-06 27.5 0.0 8.3e-06 26.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 CEP11443.1 - 0.00059 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 CEP11443.1 - 0.009 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEP11443.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 CEP11443.1 - 0.021 13.9 0.0 0.041 13.0 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Zip PF02535.17 CEP11443.1 - 0.024 13.6 0.7 0.025 13.5 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Methyltransf_26 PF13659.1 CEP11443.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CPSF73-100_C PF11718.3 CEP11443.1 - 0.14 11.5 3.0 0.24 10.7 2.1 1.4 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Innate_immun PF12782.2 CEP11443.1 - 0.5 9.5 6.0 0.65 9.1 4.2 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SelP_N PF04592.9 CEP11443.1 - 1.2 8.5 11.7 1.9 7.7 8.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Dus PF01207.12 CEP11444.1 - 1.4e-49 168.6 0.0 1.7e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Ribosomal_L34 PF00468.12 CEP11445.1 - 1.7e-19 69.2 6.2 2.7e-19 68.5 4.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Methyltransf_31 PF13847.1 CEP11445.1 - 5.4e-12 45.5 0.0 1.3e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP11445.1 - 1.2e-11 44.9 0.0 2.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP11445.1 - 7.1e-11 42.0 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP11445.1 - 3.7e-08 33.9 0.0 7.7e-07 29.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP11445.1 - 9e-08 31.5 0.0 2e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEP11445.1 - 4.2e-06 27.0 0.0 9.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP11445.1 - 2.3e-05 24.8 0.0 4.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP11445.1 - 2.8e-05 23.2 0.0 0.00023 20.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.7 CEP11445.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 CEP11445.1 - 0.0037 16.8 0.0 0.021 14.3 0.0 2.0 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CEP11445.1 - 0.011 15.0 0.0 0.059 12.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.10 CEP11445.1 - 0.013 15.0 0.0 0.041 13.5 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_26 PF13659.1 CEP11445.1 - 0.055 13.5 0.0 0.14 12.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 CEP11445.1 - 0.056 12.8 0.0 0.49 9.7 0.0 2.2 3 0 0 3 3 3 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 CEP11445.1 - 0.076 12.0 0.0 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 CEP11445.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.12 CEP11445.1 - 0.12 11.3 0.0 0.56 9.1 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family TehB PF03848.9 CEP11445.1 - 0.12 11.4 0.0 0.39 9.8 0.0 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB Usp PF00582.21 CEP11447.1 - 6.6e-25 87.9 0.3 6.4e-24 84.7 0.2 2.0 1 1 0 1 1 1 1 Universal stress protein family Pkinase PF00069.20 CEP11448.1 - 1.5e-69 234.0 0.0 2.2e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11448.1 - 1.1e-47 162.2 0.0 2.2e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CEP11448.1 - 1.3e-20 73.6 4.0 2.5e-20 72.6 0.2 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CEP11448.1 - 4.2e-06 25.9 0.0 7.5e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP11448.1 - 0.03 14.0 0.0 0.64 9.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 CEP11448.1 - 0.065 12.4 0.1 0.15 11.2 0.1 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 CEP11448.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med8 PF10232.4 CEP11449.1 - 4.6e-10 39.3 8.4 6.4e-10 38.9 5.8 1.3 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Kinesin PF00225.18 CEP11450.1 - 1.8e-112 375.3 0.0 3.3e-112 374.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 CEP11450.1 - 2.8e-22 78.8 0.0 8.7e-22 77.2 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 CEP11450.1 - 6.3e-06 26.3 0.3 2.7e-05 24.3 0.2 2.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CEP11450.1 - 0.0024 18.0 0.0 0.0099 16.1 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain F-box-like PF12937.2 CEP11451.1 - 2.8e-05 23.7 0.2 0.00011 21.8 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP11451.1 - 0.0048 16.5 1.0 0.037 13.6 0.1 2.6 2 0 0 2 2 2 1 F-box domain LRR_2 PF07723.8 CEP11451.1 - 0.0075 16.7 6.6 0.71 10.4 0.1 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.2 CEP11451.1 - 0.045 13.4 11.4 0.52 10.0 0.3 5.2 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) E1-E2_ATPase PF00122.15 CEP11452.1 - 3.4e-27 94.9 0.1 7.7e-27 93.8 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEP11452.1 - 2.1e-15 57.7 0.0 5.7e-13 49.7 0.0 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP11452.1 - 1.1e-14 55.1 0.0 1.9e-13 50.9 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP11452.1 - 0.00083 18.7 0.0 0.00083 18.7 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CEP11452.1 - 0.006 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEP11452.1 - 0.035 13.6 0.2 0.22 11.0 0.0 2.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase NAC PF01849.13 CEP11453.1 - 2.8e-19 68.3 0.5 3.1e-17 61.8 0.0 2.8 3 0 0 3 3 3 2 NAC domain UBA PF00627.26 CEP11453.1 - 3.8e-05 23.4 1.1 7e-05 22.5 0.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Ribosomal_S13 PF00416.17 CEP11453.1 - 0.064 13.7 0.9 0.64 10.4 0.2 2.3 2 1 0 2 2 2 0 Ribosomal protein S13/S18 Chalcone PF02431.10 CEP11454.1 - 7.2e-37 126.7 0.0 9.3e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase GDPD_2 PF13653.1 CEP11454.1 - 0.021 15.0 0.6 0.071 13.3 0.1 2.2 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family PAM2 PF07145.10 CEP11454.1 - 0.12 11.9 0.2 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Isy1 PF06246.7 CEP11455.1 - 5.5e-88 294.6 6.4 6.4e-88 294.4 4.5 1.0 1 0 0 1 1 1 1 Isy1-like splicing family zf-H2C2 PF09337.5 CEP11455.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger PTPS PF01242.14 CEP11456.1 - 2.9e-33 114.1 0.5 4.3e-33 113.6 0.3 1.2 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Peptidase_S15 PF02129.13 CEP11457.1 - 0.0019 17.7 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ion_trans_N PF08412.5 CEP11457.1 - 0.1 11.9 0.0 0.11 11.8 0.0 1.3 1 1 0 1 1 1 0 Ion transport protein N-terminal ACT_7 PF13840.1 CEP11458.1 - 2.7e-23 81.2 0.0 4.5e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain IFT57 PF10498.4 CEP11459.1 - 1.5 7.4 4.7 1.6 7.3 3.3 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CobT PF06213.7 CEP11459.1 - 9.7 5.2 9.1 11 5.0 6.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HTH_29 PF13551.1 CEP11460.1 - 1e-05 25.6 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP11460.1 - 0.0002 20.9 0.0 0.0004 19.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 CEP11460.1 - 0.00039 19.9 0.0 0.00071 19.1 0.0 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_psq PF05225.11 CEP11460.1 - 0.00048 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP11460.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP11460.1 - 0.0021 18.2 0.2 0.0048 17.1 0.0 1.7 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_1 PF00126.22 CEP11460.1 - 0.0027 17.4 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CENP-B_N PF04218.8 CEP11460.1 - 0.0045 16.3 0.0 0.0098 15.2 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 CEP11460.1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP11460.1 - 0.0059 17.3 0.0 0.45 11.3 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain NUMOD1 PF07453.8 CEP11460.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 NUMOD1 domain MerR_1 PF13411.1 CEP11460.1 - 0.015 15.0 0.2 0.093 12.5 0.1 2.4 2 1 0 2 2 2 0 MerR HTH family regulatory protein HTH_3 PF01381.17 CEP11460.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_8 PF02954.14 CEP11460.1 - 0.019 14.5 0.3 0.057 12.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family MarR PF01047.17 CEP11460.1 - 0.032 13.9 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.2 CEP11460.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.2 CEP11460.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.15 CEP11460.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family SpoIIID PF12116.3 CEP11460.1 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D DUF2203 PF09969.4 CEP11460.1 - 0.12 12.6 0.2 0.26 11.5 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HTH_24 PF13412.1 CEP11460.1 - 0.13 11.7 0.1 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding V_ATPase_I PF01496.14 CEP11463.1 - 2.6e-271 901.8 1.1 3e-271 901.6 0.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 CEP11463.1 - 0.0066 16.3 1.2 0.016 15.1 0.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor IncA PF04156.9 CEP11463.1 - 0.007 15.9 6.0 0.007 15.9 4.1 2.2 2 0 0 2 2 2 1 IncA protein bZIP_2 PF07716.10 CEP11463.1 - 0.032 14.0 0.4 0.073 12.9 0.3 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Angiomotin_C PF12240.3 CEP11463.1 - 0.55 9.6 5.6 1.4 8.3 3.9 1.6 1 1 0 1 1 1 0 Angiomotin C terminal BAR PF03114.13 CEP11464.1 - 2.4e-31 109.0 9.1 3.2e-31 108.6 6.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 CEP11464.1 - 1.7e-11 43.5 0.2 3e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP11464.1 - 1.5e-10 40.3 0.7 2.8e-10 39.4 0.5 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP11464.1 - 2.9e-10 39.4 0.4 5.7e-10 38.5 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 CEP11464.1 - 0.00034 19.6 5.8 0.00059 18.8 4.0 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF342 PF03961.8 CEP11464.1 - 3.2 6.0 5.8 5.3 5.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CEP11464.1 - 7 5.5 12.2 13 4.6 8.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 NDUF_B4 PF07225.7 CEP11465.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-gamma PF00631.17 CEP11466.1 - 4.5e-23 80.7 0.0 5.3e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain Orbi_VP2 PF00898.12 CEP11466.1 - 0.15 9.5 0.1 0.17 9.3 0.1 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Aconitase PF00330.15 CEP11467.1 - 3.2e-76 256.7 0.1 1.3e-75 254.7 0.1 2.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEP11467.1 - 1.3e-20 73.8 0.0 3e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 CEP11467.1 - 0.0017 16.9 0.0 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) COPIIcoated_ERV PF07970.7 CEP11468.1 - 1.1e-67 227.9 0.0 1.4e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CEP11468.1 - 5.5e-26 90.3 0.6 1.3e-21 76.3 0.0 2.4 2 0 0 2 2 2 2 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SET PF00856.23 CEP11469.1 - 9.2e-10 39.0 0.2 2.8e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 CEP11469.1 - 3e-07 30.2 7.7 3e-07 30.2 5.3 3.6 2 1 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CEP11469.1 - 0.12 12.2 15.2 0.65 9.9 4.5 3.5 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 SPRY PF00622.23 CEP11470.1 - 1.2e-20 73.8 0.1 2.1e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 CEP11470.1 - 8.4e-18 64.4 0.0 1.4e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CEP11470.1 - 0.00013 21.5 0.0 0.00034 20.2 0.0 1.7 1 0 0 1 1 1 1 LisH CENP-B_N PF04218.8 CEP11471.1 - 0.00035 19.9 0.1 0.00056 19.2 0.1 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Trp_syntA PF00290.15 CEP11472.1 - 1.9e-94 315.0 0.4 3.1e-94 314.3 0.1 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 CEP11472.1 - 2.3e-45 155.1 0.3 3.9e-45 154.4 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 CEP11472.1 - 0.066 12.4 0.2 0.18 11.0 0.1 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein Cyclin PF08613.6 CEP11473.1 - 6.2e-34 117.5 0.7 1.5e-33 116.3 0.5 1.6 1 0 0 1 1 1 1 Cyclin Lipase_3 PF01764.20 CEP11473.1 - 3e-17 62.5 0.0 5.3e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Methyltransf_12 PF08242.7 CEP11474.1 - 8.6e-15 55.0 0.0 2.4e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP11474.1 - 2.8e-12 46.6 0.0 4.9e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP11474.1 - 4.9e-11 42.4 0.1 8.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP11474.1 - 2.5e-09 37.5 0.0 5.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP11474.1 - 6.6e-08 33.1 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP11474.1 - 6.1e-07 28.9 0.0 1.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CEP11474.1 - 7.9e-06 26.1 0.0 2.1e-05 24.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP11474.1 - 1.3e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CEP11474.1 - 2e-05 24.5 0.0 5.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 CEP11474.1 - 7.7e-05 21.8 0.1 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 CEP11474.1 - 0.00047 19.6 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.12 CEP11474.1 - 0.0016 17.4 0.0 0.0072 15.3 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase DOT1 PF08123.8 CEP11474.1 - 0.0019 17.5 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 NodS PF05401.6 CEP11474.1 - 0.0027 17.1 0.0 0.0075 15.6 0.0 1.6 1 1 0 1 1 1 1 Nodulation protein S (NodS) tRNA_U5-meth_tr PF05958.6 CEP11474.1 - 0.0038 15.9 0.1 0.0038 15.9 0.0 1.6 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_9 PF08003.6 CEP11474.1 - 0.06 12.0 0.0 0.085 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TauD PF02668.11 CEP11475.1 - 5.8e-56 190.0 0.1 7.9e-56 189.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CEP11475.1 - 0.0026 18.1 0.1 0.0077 16.6 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF971) Lipase_3 PF01764.20 CEP11476.1 - 2.8e-14 52.9 0.0 5.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CEP11476.1 - 0.042 13.7 0.1 0.059 13.2 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2012 PF09430.5 CEP11477.1 - 1.3e-27 96.0 0.1 1.9e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.1 CEP11477.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 CEP11477.1 - 0.032 14.2 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Glyco_transf_8 PF01501.15 CEP11479.1 - 3.3e-33 115.0 1.5 4.4e-33 114.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CEP11479.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Transferase PF02458.10 CEP11480.1 - 4.9e-36 124.1 0.0 5.8e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 CEP11480.1 - 0.0029 16.4 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Ribonuc_red_lgC PF02867.10 CEP11481.1 - 4.8e-212 705.3 0.0 6.8e-212 704.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CEP11481.1 - 1.4e-23 82.5 0.0 3.6e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CEP11481.1 - 4.6e-16 59.0 0.1 1.4e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 CEP11481.1 - 0.0023 16.0 0.0 0.0036 15.4 0.0 1.3 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Y_phosphatase2 PF03162.8 CEP11481.1 - 0.089 12.1 0.1 0.22 10.8 0.1 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family PAT1 PF09770.4 CEP11482.1 - 2.4 6.2 16.1 3.1 5.9 11.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UDPGP PF01704.13 CEP11485.1 - 2.9e-174 579.5 1.9 5.4e-172 572.0 1.3 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase rRNA_processing PF08524.6 CEP11486.1 - 2e-09 37.4 33.1 5.7e-08 32.6 14.6 2.3 1 1 1 2 2 2 2 rRNA processing UvsY PF11056.3 CEP11486.1 - 0.023 14.8 2.6 0.023 14.8 1.8 1.7 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY ABA_GPCR PF12430.3 CEP11487.1 - 8.6e-35 119.6 6.4 1.6e-34 118.7 4.4 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor Cullin_binding PF03556.10 CEP11487.1 - 1e-29 103.0 6.7 1e-29 103.0 4.7 2.0 2 0 0 2 2 2 1 Cullin binding DUF3735 PF12537.3 CEP11487.1 - 2.3e-16 59.5 0.2 1.2e-15 57.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) DUF2962 PF11176.3 CEP11487.1 - 0.036 13.6 1.9 0.04 13.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2962) HNH PF01844.18 CEP11490.1 - 0.018 14.9 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 HNH endonuclease Defensin_beta_2 PF13841.1 CEP11490.1 - 0.12 12.7 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Beta defensin zf-CCHC PF00098.18 CEP11490.1 - 0.14 12.1 0.8 0.26 11.2 0.4 1.6 1 1 1 2 2 2 0 Zinc knuckle CLN3 PF02487.12 CEP11491.1 - 0.14 10.9 1.7 0.19 10.4 1.2 1.2 1 0 0 1 1 1 0 CLN3 protein DUF4643 PF15485.1 CEP11492.1 - 0.0025 17.3 7.9 0.0032 17.0 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4643) DUF2630 PF10944.3 CEP11492.1 - 0.066 13.3 2.2 0.11 12.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) CHAD PF05235.9 CEP11492.1 - 0.18 11.3 1.7 0.2 11.2 1.2 1.1 1 0 0 1 1 1 0 CHAD domain CPSF100_C PF13299.1 CEP11492.1 - 0.23 11.6 3.2 0.33 11.1 2.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Allexi_40kDa PF05549.6 CEP11492.1 - 0.83 8.8 3.8 0.97 8.6 2.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2968 PF11180.3 CEP11492.1 - 6.9 5.9 9.6 3.3 7.0 5.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) rve PF00665.21 CEP11495.1 - 2.6e-14 53.3 0.0 3.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP11495.1 - 0.0052 16.2 0.1 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CEP11497.1 - 8.4e-10 39.0 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP11497.1 - 0.00036 20.3 0.1 0.00036 20.3 0.0 2.2 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CEP11497.1 - 0.0055 16.5 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.7 CEP11497.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Herpes_ori_bp PF02399.10 CEP11498.1 - 5.3e-08 31.3 0.0 6.7e-08 30.9 0.0 1.0 1 0 0 1 1 1 1 Origin of replication binding protein UPF0079 PF02367.12 CEP11498.1 - 3.5e-05 23.4 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 CEP11498.1 - 7.7e-05 22.8 0.0 0.0002 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CEP11498.1 - 0.00093 19.1 0.1 0.003 17.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CEP11498.1 - 0.0012 18.7 0.2 0.022 14.6 0.1 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CEP11498.1 - 0.0023 17.6 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 CEP11498.1 - 0.0035 17.5 0.0 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CEP11498.1 - 0.0054 16.6 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CEP11498.1 - 0.013 15.2 0.0 0.041 13.5 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 CEP11498.1 - 0.031 15.0 0.1 0.26 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain ThiF PF00899.16 CEP11498.1 - 0.042 13.6 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 ThiF family AAA_30 PF13604.1 CEP11498.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Chromo PF00385.19 CEP11499.1 - 5.4e-07 29.1 0.1 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNase_H PF00075.19 CEP11500.1 - 0.15 12.4 0.0 0.5 10.7 0.0 1.8 2 1 0 2 2 2 0 RNase H DUF1835 PF08874.5 CEP11501.1 - 0.065 13.1 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) SLX9 PF15341.1 CEP11501.1 - 0.067 13.6 0.0 0.075 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Rick_17kDa_Anti PF05433.10 CEP11501.1 - 3.6 7.3 13.4 13 5.5 9.3 1.9 1 1 0 1 1 1 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 CEP11501.1 - 5 7.3 10.8 6.5 6.9 5.2 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Retrotrans_gag PF03732.12 CEP11502.1 - 0.008 16.2 0.8 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Myb_DNA-bind_6 PF13921.1 CEP11503.1 - 3.2e-05 23.9 0.5 7e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP11503.1 - 0.029 14.4 0.4 0.075 13.0 0.3 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1835 PF08874.5 CEP11503.1 - 0.057 13.3 0.0 0.2 11.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1835) AT_hook PF02178.14 CEP11503.1 - 0.2 11.4 5.2 0.42 10.4 3.6 1.6 1 0 0 1 1 1 0 AT hook motif Glyco_tran_WbsX PF14307.1 CEP11504.1 - 3.3 6.7 9.0 6 5.9 6.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase WbsX RasGAP PF00616.14 CEP11505.1 - 2.1e-39 135.2 0.5 4.1e-39 134.2 0.4 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PH PF00169.24 CEP11505.1 - 7.3e-06 26.1 2.7 0.00046 20.3 0.0 3.4 3 0 0 3 3 3 1 PH domain C2 PF00168.25 CEP11505.1 - 0.015 15.1 0.0 0.045 13.5 0.0 1.9 1 0 0 1 1 1 0 C2 domain CENP-B_dimeris PF09026.5 CEP11505.1 - 0.39 10.9 6.9 1.3 9.2 4.8 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RasGEF PF00617.14 CEP11506.1 - 7.9e-44 149.6 0.7 1.5e-43 148.7 0.5 1.4 1 0 0 1 1 1 1 RasGEF domain DNA_pol_phi PF04931.8 CEP11506.1 - 8.6 3.9 17.3 26 2.4 12.0 1.7 1 0 0 1 1 1 0 DNA polymerase phi Acyl_CoA_thio PF02551.10 CEP11507.1 - 5.8e-33 113.3 0.0 3.3e-27 94.7 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 CEP11507.1 - 2.4e-32 112.7 0.0 3.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Transaldolase PF00923.14 CEP11508.1 - 1.2e-103 346.1 0.8 1.4e-103 345.9 0.5 1.0 1 0 0 1 1 1 1 Transaldolase TFIIIC_sub6 PF10419.4 CEP11509.1 - 1.1e-06 27.9 0.2 1.6e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 TFIIIC subunit Lipase_3 PF01764.20 CEP11510.1 - 4.3e-25 87.9 0.2 2.1e-23 82.5 0.1 2.4 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 CEP11510.1 - 0.078 12.2 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) FAM104 PF15434.1 CEP11511.1 - 2.1 8.5 5.4 0.62 10.2 1.2 1.9 2 0 0 2 2 2 0 Family 104 RhoGEF PF00621.15 CEP11512.1 - 2.1e-34 118.9 8.8 2.1e-34 118.9 6.1 2.1 2 0 0 2 2 2 1 RhoGEF domain HeLo PF14479.1 CEP11512.1 - 0.023 14.4 0.1 0.023 14.4 0.1 2.4 2 0 0 2 2 2 0 Prion-inhibition and propagation zf-H2C2_2 PF13465.1 CEP11514.1 - 7.4e-15 54.4 19.6 7.7e-08 32.2 0.6 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEP11514.1 - 9.8e-14 50.7 19.4 5e-05 23.3 0.3 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP11514.1 - 3.1e-11 42.7 16.7 0.00052 20.1 0.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP11514.1 - 1.3e-05 25.1 7.0 0.1 12.7 0.0 4.0 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP11514.1 - 0.0021 18.1 7.2 0.031 14.4 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CEP11514.1 - 0.041 13.5 0.6 0.11 12.1 0.4 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 CEP11514.1 - 0.053 13.4 0.2 0.053 13.4 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Methyltransf_11 PF08241.7 CEP11515.1 - 1e-18 67.6 0.0 2.5e-18 66.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP11515.1 - 9.6e-18 64.2 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP11515.1 - 2.6e-17 63.0 0.1 5.9e-17 61.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP11515.1 - 4.3e-17 62.4 0.0 7.2e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP11515.1 - 1.1e-14 54.9 0.0 4.2e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP11515.1 - 2.8e-10 40.4 0.0 4.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CEP11515.1 - 1.2e-08 33.9 0.0 1.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 CEP11515.1 - 3e-07 29.9 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 CEP11515.1 - 2.6e-06 27.0 0.0 5.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 CEP11515.1 - 1e-05 25.0 0.0 2.9e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.15 CEP11515.1 - 2.6e-05 23.3 0.0 3.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 CEP11515.1 - 4.9e-05 22.5 0.0 6.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 CEP11515.1 - 6.2e-05 22.6 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEP11515.1 - 6.5e-05 22.1 0.0 8.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 CEP11515.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 CEP11515.1 - 0.00016 21.2 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CEP11515.1 - 0.0002 21.3 0.0 0.00047 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CEP11515.1 - 0.00046 19.1 0.0 0.00089 18.2 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 CEP11515.1 - 0.00047 19.3 0.0 0.0011 18.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 CEP11515.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.8 CEP11515.1 - 0.1 12.6 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase MCM PF00493.18 CEP11516.1 - 5.8e-142 472.3 0.3 7.8e-142 471.9 0.2 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CEP11516.1 - 9.2e-19 68.1 0.5 9.2e-19 68.1 0.3 2.3 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.3 CEP11516.1 - 2.4e-15 56.8 24.9 2.4e-15 56.8 17.2 3.0 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.16 CEP11516.1 - 9.5e-09 34.7 0.1 1.1e-06 27.9 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CEP11516.1 - 3.9e-05 23.3 0.0 9.1e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CEP11516.1 - 0.00012 21.6 0.0 0.0029 17.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CEP11516.1 - 0.039 13.4 0.1 0.38 10.2 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF1642 PF07852.6 CEP11516.1 - 0.051 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Abhydrolase_3 PF07859.8 CEP11517.1 - 4.4e-52 176.7 0.0 5.5e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP11517.1 - 4.8e-05 23.1 0.0 7.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP11517.1 - 0.0019 17.4 0.0 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 CEP11517.1 - 0.0052 15.5 0.0 1 7.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family AXE1 PF05448.7 CEP11517.1 - 0.019 13.4 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) SDH_sah PF01972.11 CEP11517.1 - 0.05 12.3 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Chlorophyllase2 PF12740.2 CEP11517.1 - 0.13 11.1 0.0 0.27 10.0 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF3020 PF11223.3 CEP11518.1 - 6e-17 61.7 5.2 6e-17 61.7 3.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) RRM_1 PF00076.17 CEP11518.1 - 8.6e-10 38.1 0.0 2.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP11518.1 - 4.3e-08 32.8 0.7 1.3e-07 31.3 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP11518.1 - 5.6e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1903 PF08991.5 CEP11519.1 - 0.11 12.6 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Waikav_capsid_1 PF12264.3 CEP11520.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Lipase_GDSL_3 PF14606.1 CEP11520.1 - 0.022 14.5 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Fer2_4 PF13510.1 CEP11520.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain GPI-anchored PF10342.4 CEP11520.1 - 0.29 11.6 3.8 5.2 7.6 0.5 2.4 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_15 PF00723.16 CEP11521.1 - 1.4e-121 406.2 0.0 9.5e-121 403.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 SHNi-TPR PF10516.4 CEP11521.1 - 0.13 11.5 1.7 0.28 10.4 0.1 2.2 2 0 0 2 2 2 0 SHNi-TPR Enolase_C PF00113.17 CEP11522.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain zf-CCHC PF00098.18 CEP11523.1 - 2e-06 27.4 3.1 0.0083 16.0 0.1 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-H2C2_2 PF13465.1 CEP11523.1 - 0.0051 17.0 0.8 9.5 6.7 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 CEP11523.1 - 0.0074 15.4 5.5 1.7 7.9 0.1 3.4 3 0 0 3 3 3 1 zinc-ribbon domain FYDLN_acid PF09538.5 CEP11523.1 - 0.019 15.5 13.6 0.024 15.1 2.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.5 CEP11523.1 - 0.12 12.3 5.3 2.2 8.2 0.1 3.5 3 0 0 3 3 3 0 Zinc ribbon domain zf-FCS PF06467.9 CEP11523.1 - 0.13 11.9 0.9 9.3 5.9 0.0 3.1 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif FdhE PF04216.7 CEP11523.1 - 0.13 11.9 2.9 0.24 11.0 0.3 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Sgf11 PF08209.6 CEP11523.1 - 0.19 11.0 4.8 4.8 6.5 0.2 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) GATA PF00320.22 CEP11523.1 - 0.19 11.0 2.4 11 5.5 0.0 3.1 3 0 0 3 3 3 0 GATA zinc finger HypA PF01155.14 CEP11523.1 - 0.23 11.1 9.9 2.4 7.8 2.6 2.8 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family BUD22 PF09073.5 CEP11523.1 - 0.25 10.3 6.2 0.38 9.7 4.3 1.3 1 0 0 1 1 1 0 BUD22 zinc_ribbon_2 PF13240.1 CEP11523.1 - 0.3 10.6 4.7 3 7.4 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 CEP11523.1 - 0.72 9.5 8.6 1.5 8.5 0.1 3.4 3 0 0 3 3 3 0 Nudix N-terminal PhnA_Zn_Ribbon PF08274.7 CEP11523.1 - 1.2 8.9 6.3 1.3 8.8 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Prok-RING_1 PF14446.1 CEP11523.1 - 1.3 8.8 9.7 9.5 6.0 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.6 CEP11523.1 - 1.6 8.4 9.2 7.1 6.3 0.5 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 CEP11523.1 - 2.8 7.8 11.0 5.3 6.9 0.3 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Astro_capsid PF03115.9 CEP11523.1 - 3 5.9 4.9 2.9 6.0 3.0 1.3 1 1 0 1 1 1 0 Astrovirus capsid protein precursor DUF2457 PF10446.4 CEP11523.1 - 4.6 5.8 15.9 9.3 4.8 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) C1_3 PF07649.7 CEP11523.1 - 6.5 6.8 6.4 13 5.9 0.4 3.2 3 0 0 3 3 3 0 C1-like domain PIF1 PF05970.9 CEP11524.1 - 1.7e-30 106.2 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP11524.1 - 0.00013 19.9 0.0 0.00015 19.6 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP11524.1 - 0.0086 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PLDc PF00614.17 CEP11525.1 - 0.045 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Phospholipase D Active site motif rve PF00665.21 CEP11526.1 - 1.1e-19 70.6 0.0 2.5e-19 69.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CEP11526.1 - 6.3e-06 25.6 0.1 4.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CEP11526.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 DDE domain YopR_core PF09025.5 CEP11528.1 - 0.012 15.5 0.2 0.021 14.8 0.2 1.3 1 0 0 1 1 1 0 YopR Core HMG_box PF00505.14 CEP11529.1 - 1.4e-08 34.8 7.4 1.7e-05 25.0 1.2 3.6 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP11529.1 - 2.3e-07 31.0 0.1 2.3e-07 31.0 0.1 3.4 3 1 0 3 3 3 2 HMG-box domain Daxx PF03344.10 CEP11529.1 - 0.0025 16.4 23.6 0.0026 16.3 16.3 1.1 1 0 0 1 1 1 1 Daxx Family YABBY PF04690.8 CEP11529.1 - 0.44 10.7 7.9 0.8 9.9 5.5 1.5 1 0 0 1 1 1 0 YABBY protein CENP-T PF15511.1 CEP11529.1 - 0.66 9.1 18.7 0.9 8.7 12.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ndc1_Nup PF09531.5 CEP11529.1 - 4 5.7 7.6 4.7 5.5 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Prog_receptor PF02161.10 CEP11529.1 - 5.6 5.6 12.2 7.1 5.3 8.5 1.1 1 0 0 1 1 1 0 Progesterone receptor PLDc PF00614.17 CEP11530.1 - 3.5e-17 61.6 1.2 3.1e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CEP11530.1 - 7.2e-13 48.3 0.3 1.4e-07 31.2 0.0 3.5 3 0 0 3 3 3 2 PLD-like domain PX PF00787.19 CEP11530.1 - 1.3e-10 41.0 1.7 1.9e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 PX domain PH PF00169.24 CEP11530.1 - 2.3e-07 30.9 0.4 8.1e-07 29.1 0.3 2.0 1 0 0 1 1 1 1 PH domain Mito_fiss_reg PF05308.6 CEP11530.1 - 0.06 12.7 8.1 0.16 11.3 5.6 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 CEP11530.1 - 0.13 11.5 5.3 0.24 10.6 3.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pap_E4 PF02711.9 CEP11530.1 - 0.4 11.5 7.2 0.14 13.0 1.9 2.4 2 0 0 2 2 2 0 E4 protein HMG-CoA_red PF00368.13 CEP11531.1 - 7.6e-164 544.7 3.0 1.1e-163 544.3 2.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Zip PF02535.17 CEP11531.1 - 0.0045 16.0 0.7 0.0078 15.2 0.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter CPSF73-100_C PF11718.3 CEP11531.1 - 0.052 12.8 0.8 0.092 12.0 0.5 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Calcipressin PF04847.7 CEP11532.1 - 1.8e-30 105.8 1.2 5.5e-30 104.3 0.8 1.8 1 1 0 1 1 1 1 Calcipressin DUF3087 PF11286.3 CEP11532.1 - 0.069 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF3343 PF11823.3 CEP11532.1 - 0.12 11.6 0.8 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) MAS20 PF02064.10 CEP11533.1 - 1.9e-13 50.3 0.1 2.2e-12 46.9 0.0 2.2 1 1 0 1 1 1 1 MAS20 protein import receptor Tox-WTIP PF15654.1 CEP11533.1 - 0.37 10.4 2.6 0.37 10.4 0.2 2.1 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif AAA_32 PF13654.1 CEP11534.1 - 0.0023 16.6 2.2 0.0025 16.5 1.5 1.0 1 0 0 1 1 1 1 AAA domain Inos-1-P_synth PF01658.12 CEP11534.1 - 0.022 14.5 0.9 0.029 14.1 0.6 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF2654 PF10849.3 CEP11534.1 - 0.33 10.6 5.0 0.77 9.5 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) ECIST_Cterm PF14784.1 CEP11534.1 - 0.41 10.6 3.3 0.51 10.2 2.3 1.2 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein MAS20 PF02064.10 CEP11535.1 - 2.2e-22 79.2 0.6 2.2e-22 79.2 0.4 2.3 3 1 0 3 3 3 1 MAS20 protein import receptor SET PF00856.23 CEP11535.1 - 4.6e-06 27.0 2.9 8.7e-05 22.8 0.2 3.0 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 CEP11535.1 - 0.00011 22.0 8.6 0.00018 21.3 6.0 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 CEP11535.1 - 0.0015 18.3 7.6 0.0035 17.1 5.3 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF581 PF04570.9 CEP11535.1 - 0.0067 15.6 4.3 0.019 14.2 3.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF581) PEP-utilisers_N PF05524.8 CEP11535.1 - 0.043 13.6 0.2 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF2681 PF10883.3 CEP11535.1 - 0.054 13.7 1.5 0.15 12.3 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) zf-HIT PF04438.11 CEP11535.1 - 0.96 9.1 5.4 2 8.1 3.7 1.5 1 0 0 1 1 1 0 HIT zinc finger Pkinase PF00069.20 CEP11537.1 - 2.7e-72 243.0 0.0 8.3e-72 241.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11537.1 - 1.2e-39 135.9 0.0 2.5e-39 134.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CEP11537.1 - 1.7e-05 23.9 0.0 3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP11537.1 - 0.00017 21.3 0.1 0.0014 18.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP11537.1 - 0.00097 18.7 0.1 0.0032 17.0 0.1 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 CEP11537.1 - 0.0097 14.8 0.0 0.024 13.5 0.0 1.7 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CEP11537.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_L2_C PF03947.13 CEP11538.1 - 4.1e-42 143.0 2.0 4.1e-42 143.0 1.4 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CEP11538.1 - 8.6e-16 57.6 0.1 2.2e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain COPIIcoated_ERV PF07970.7 CEP11540.1 - 7e-39 133.7 1.1 9.3e-39 133.3 0.8 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CEP11540.1 - 5.5e-09 35.8 0.0 0.0021 18.0 0.0 2.5 1 1 1 2 2 2 2 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AAA PF00004.24 CEP11541.1 - 1.1e-44 151.7 0.2 3.9e-44 150.0 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEP11541.1 - 1.8e-09 37.4 0.1 5.3e-09 35.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CEP11541.1 - 5.5e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CEP11541.1 - 3.9e-07 30.2 0.0 1.6e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CEP11541.1 - 5.1e-06 26.6 1.0 0.00074 19.6 0.5 2.7 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CEP11541.1 - 8.4e-06 24.8 0.0 1.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 CEP11541.1 - 0.00014 21.5 0.1 0.00038 20.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CEP11541.1 - 0.00019 21.3 0.0 0.00092 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CEP11541.1 - 0.00021 21.3 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CEP11541.1 - 0.0003 20.4 0.1 0.015 14.8 0.0 2.4 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 CEP11541.1 - 0.00045 19.3 0.0 0.0012 17.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CEP11541.1 - 0.00052 19.4 0.7 0.012 15.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP11541.1 - 0.00078 20.2 0.0 0.0054 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEP11541.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 CEP11541.1 - 0.0021 17.8 0.0 0.007 16.0 0.0 1.9 1 0 0 1 1 1 1 NTPase AAA_11 PF13086.1 CEP11541.1 - 0.0026 17.3 0.9 0.0082 15.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CEP11541.1 - 0.003 16.3 0.0 0.0054 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NACHT PF05729.7 CEP11541.1 - 0.0031 17.2 0.1 0.053 13.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 CEP11541.1 - 0.0037 16.7 0.0 0.0097 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CEP11541.1 - 0.0054 16.6 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CEP11541.1 - 0.0071 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 CEP11541.1 - 0.0073 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CEP11541.1 - 0.0076 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CEP11541.1 - 0.0094 16.2 0.1 0.051 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 CEP11541.1 - 0.013 14.5 0.8 0.45 9.5 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.1 CEP11541.1 - 0.014 14.9 0.1 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CEP11541.1 - 0.016 14.9 0.4 0.23 11.1 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_23 PF13476.1 CEP11541.1 - 0.016 15.5 3.2 0.63 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CEP11541.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 CEP11541.1 - 0.026 14.8 0.2 0.39 11.0 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 CEP11541.1 - 0.046 13.2 0.1 1.2 8.5 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.13 CEP11541.1 - 0.048 13.2 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.12 CEP11541.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CEP11541.1 - 0.14 12.1 0.2 0.67 9.9 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain F-box-like PF12937.2 CEP11542.1 - 5.9e-12 45.1 0.5 5.9e-12 45.1 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP11542.1 - 6.4e-06 25.6 0.1 1.5e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain DMA PF03474.9 CEP11542.1 - 0.034 13.9 0.3 1.5 8.7 0.0 3.1 3 0 0 3 3 3 0 DMRTA motif IQ PF00612.22 CEP11543.1 - 7.2e-06 25.1 0.1 1.9e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif CK2S PF15011.1 CEP11543.1 - 4.9e-05 23.1 3.1 7.3e-05 22.6 1.4 2.0 1 1 0 1 1 1 1 Casein Kinase 2 substrate Lzipper-MIP1 PF14389.1 CEP11543.1 - 0.0041 17.1 14.6 0.035 14.1 1.3 3.3 2 1 1 3 3 3 2 Leucine-zipper of ternary complex factor MIP1 DUF1664 PF07889.7 CEP11543.1 - 0.19 11.5 6.1 0.45 10.3 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HR1 PF02185.11 CEP11543.1 - 0.69 9.6 11.6 0.11 12.2 4.1 2.4 1 1 1 2 2 2 0 Hr1 repeat MFS_1 PF07690.11 CEP11544.1 - 3.3e-22 78.6 37.0 3.3e-22 78.6 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PCI_Csn8 PF10075.4 CEP11545.1 - 6.2e-17 61.7 0.3 8.3e-17 61.2 0.2 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 CEP11545.1 - 3.3e-05 24.1 0.4 5.5e-05 23.4 0.2 1.4 1 1 0 1 1 1 1 PCI domain Herpes_BBRF1 PF04793.7 CEP11545.1 - 0.03 13.1 0.8 0.037 12.7 0.6 1.1 1 0 0 1 1 1 0 BRRF1-like protein tRNA-synt_1d PF00750.14 CEP11545.1 - 0.074 11.8 0.1 0.089 11.5 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) SAC3_GANP PF03399.11 CEP11545.1 - 0.083 12.4 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2877 PF11392.3 CEP11545.1 - 0.1 12.7 0.5 0.21 11.8 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) GPI-anchored PF10342.4 CEP11549.1 - 4.1e-08 33.5 0.5 4.1e-08 33.5 0.3 1.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAD_kinase PF01513.16 CEP11550.1 - 5.2e-66 222.3 0.0 3.6e-40 137.5 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase zf-Mss51 PF13824.1 CEP11551.1 - 4.6e-17 61.6 10.9 4.6e-17 61.6 7.5 1.9 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-TFIIB PF13453.1 CEP11551.1 - 0.056 12.6 3.9 0.11 11.6 2.7 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Rad50_zn_hook PF04423.9 CEP11551.1 - 0.084 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif DNA_ligase_ZBD PF03119.11 CEP11551.1 - 0.11 12.2 0.3 0.11 12.2 0.2 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.2 CEP11551.1 - 0.13 12.0 2.4 0.28 11.0 1.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 CEP11551.1 - 0.41 10.3 3.4 0.85 9.3 2.4 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RNA_POL_M_15KD PF02150.11 CEP11551.1 - 1 9.0 4.0 2.5 7.8 2.8 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit EamA PF00892.15 CEP11553.1 - 1.9e-08 34.4 11.4 1.4e-05 25.1 1.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CEP11553.1 - 5.3e-08 32.2 3.4 7.5e-08 31.7 2.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF1352 PF07086.7 CEP11553.1 - 0.024 14.2 2.6 0.041 13.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) DUF914 PF06027.7 CEP11553.1 - 0.83 8.4 13.1 0.068 11.9 2.8 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Rft-1 PF04506.8 CEP11554.1 - 6.3e-99 331.8 35.2 6.9e-98 328.3 24.4 1.9 1 1 0 1 1 1 1 Rft protein Arif-1 PF06770.6 CEP11554.1 - 7.5 5.8 16.5 0.16 11.3 0.3 3.3 3 1 1 4 4 4 0 Actin-rearrangement-inducing factor (Arif-1) Cupin_8 PF13621.1 CEP11556.1 - 1.4e-33 116.4 0.1 2.1e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CEP11556.1 - 0.00049 19.4 0.3 0.00098 18.4 0.2 1.6 1 0 0 1 1 1 1 Cupin superfamily protein RloB PF13707.1 CEP11556.1 - 0.072 12.7 0.1 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 RloB-like protein Ribosomal_S9 PF00380.14 CEP11557.1 - 1.2e-39 135.3 0.3 1.9e-39 134.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF3885 PF13021.1 CEP11557.1 - 0.25 11.0 7.3 3.4 7.4 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3885) Fcf1 PF04900.7 CEP11558.1 - 1.2e-22 79.8 0.9 4.1e-22 78.1 0.0 2.1 2 1 0 2 2 2 1 Fcf1 CBS PF00571.23 CEP11559.1 - 5.6e-36 122.0 10.9 6.1e-09 35.5 0.0 5.4 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 CEP11559.1 - 1.5e-10 40.6 0.1 4.3e-10 39.1 0.1 1.9 1 0 0 1 1 1 1 PB1 domain DUF4611 PF15387.1 CEP11559.1 - 0.15 12.1 5.0 0.67 10.1 3.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF4597 PF15366.1 CEP11559.1 - 0.94 9.1 7.6 0.25 10.9 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) tRNA-synt_1b PF00579.20 CEP11560.1 - 7.2e-24 84.4 0.0 2.1e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) EFP_N PF08207.7 CEP11561.1 - 2.7e-15 55.9 0.1 5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.6 CEP11561.1 - 7.1e-14 50.8 0.5 1.4e-13 49.9 0.4 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.15 CEP11561.1 - 8.7e-08 31.7 0.1 2.1e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain GTP_EFTU_D3 PF03143.12 CEP11561.1 - 0.066 13.3 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain Myosin_HC-like PF07058.6 CEP11562.1 - 0.7 8.9 4.1 0.42 9.6 1.5 1.5 1 1 0 1 1 1 0 Myosin II heavy chain-like Hydrolase_like2 PF13246.1 CEP11563.1 - 5.9e-14 51.7 0.0 3.1e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP11563.1 - 3.2e-13 50.2 0.1 1.2e-12 48.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEP11563.1 - 4.6e-13 48.7 0.1 8.1e-07 28.3 0.0 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 CEP11563.1 - 1.2e-10 42.1 1.3 5.6e-09 36.7 0.9 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP11563.1 - 7.2e-05 22.4 0.1 0.00036 20.2 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Transketolase_N PF00456.16 CEP11564.1 - 1.1e-128 428.7 0.0 1.6e-128 428.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CEP11564.1 - 1.5e-42 145.0 0.0 2.9e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CEP11564.1 - 8.6e-11 41.8 0.0 2.1e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CEP11564.1 - 1.4e-05 24.1 0.0 0.0029 16.6 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CEP11564.1 - 0.00061 18.5 0.0 0.0011 17.7 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.16 CEP11564.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain IF2_N PF04760.10 CEP11564.1 - 0.028 14.0 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region UPF0066 PF01980.11 CEP11564.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0066 Glyco_transf_28 PF03033.15 CEP11565.1 - 1.5e-22 79.8 0.0 3.3e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CEP11565.1 - 4.1e-12 45.4 0.1 3.8e-11 42.3 0.0 2.6 3 0 0 3 3 3 1 GRAM domain UDPGT PF00201.13 CEP11565.1 - 6.4e-06 25.0 0.0 0.0001 21.0 0.0 2.2 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase SNARE PF05739.14 CEP11567.1 - 4.8e-18 64.6 4.0 4.8e-18 64.6 2.8 2.6 3 1 1 4 4 4 1 SNARE domain Syntaxin PF00804.20 CEP11567.1 - 0.0002 21.4 0.9 0.0002 21.4 0.6 2.7 2 1 0 2 2 2 1 Syntaxin DASH_Duo1 PF08651.5 CEP11567.1 - 0.0034 16.9 1.0 6.9 6.3 0.0 3.7 3 1 1 4 4 4 1 DASH complex subunit Duo1 MCPsignal PF00015.16 CEP11567.1 - 0.026 14.0 1.2 0.026 14.0 0.8 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 CEP11567.1 - 0.12 12.5 6.0 0.063 13.4 2.0 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2116 PF09889.4 CEP11567.1 - 0.12 12.2 2.3 0.24 11.2 1.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DNA_repr_REX1B PF14966.1 CEP11567.1 - 0.49 10.8 4.3 2.8 8.3 0.8 3.3 3 1 0 3 3 3 0 DNA repair REX1-B H-kinase_dim PF02895.9 CEP11567.1 - 1.3 9.3 5.7 18 5.7 4.0 2.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF1664 PF07889.7 CEP11567.1 - 4 7.2 8.9 4.4 7.1 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) PMT PF02366.13 CEP11568.1 - 3.1e-74 249.4 22.1 8.3e-74 248.0 15.3 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEP11568.1 - 4.8e-13 49.0 1.0 8.9e-13 48.1 0.4 1.6 1 1 1 2 2 2 2 MIR domain Redoxin PF08534.5 CEP11569.1 - 3.9e-31 107.5 0.0 5.5e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin MPP6 PF10175.4 CEP11569.1 - 4.5e-10 39.8 4.4 9e-10 38.8 3.1 1.5 1 0 0 1 1 1 1 M-phase phosphoprotein 6 AhpC-TSA PF00578.16 CEP11569.1 - 9.1e-10 38.2 0.2 2.2e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family HAD PF12710.2 CEP11569.1 - 0.00022 21.4 0.0 0.00045 20.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec8_exocyst PF04048.9 CEP11570.1 - 5e-38 129.9 0.1 5e-38 129.9 0.1 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2451 PF10474.4 CEP11570.1 - 0.00049 19.9 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Ribonuclease_3 PF00636.21 CEP11571.1 - 8.8e-41 138.9 0.0 5.1e-21 75.2 0.0 3.3 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 CEP11571.1 - 8.3e-22 76.7 0.0 2.2e-20 72.2 0.0 2.8 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 CEP11571.1 - 4.7e-19 68.6 0.0 3.7e-13 49.5 0.0 3.9 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.26 CEP11571.1 - 6.5e-18 64.3 0.1 1.8e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP11571.1 - 1.6e-11 44.3 0.2 4.6e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEP11571.1 - 3.2e-11 43.0 0.0 6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PAZ PF02170.17 CEP11571.1 - 1.1e-08 34.4 0.1 2.7e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 PAZ domain SecA_DEAD PF07517.9 CEP11571.1 - 0.0047 16.2 0.1 0.013 14.8 0.1 1.7 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 CEP11571.1 - 0.12 12.5 0.1 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain COX5A PF02284.11 CEP11572.1 - 4e-40 136.1 0.1 5.2e-40 135.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Tricorn_C1 PF14684.1 CEP11572.1 - 0.1 12.4 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease C1 domain Peptidase_M41 PF01434.13 CEP11573.1 - 1.3e-74 250.2 0.0 1.9e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CEP11573.1 - 1e-43 148.6 0.0 3.1e-43 147.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CEP11573.1 - 4.3e-10 39.7 0.1 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CEP11573.1 - 0.00052 20.8 0.0 0.0028 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP11573.1 - 0.00096 19.2 0.1 0.19 11.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CEP11573.1 - 0.0013 17.8 0.0 0.0028 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CEP11573.1 - 0.0038 15.9 0.1 0.0059 15.3 0.1 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 CEP11573.1 - 0.0041 16.8 0.7 0.014 15.1 0.5 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CEP11573.1 - 0.0061 16.2 0.0 0.026 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP11573.1 - 0.0089 16.0 0.1 0.11 12.5 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 CEP11573.1 - 0.024 13.7 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 CEP11573.1 - 0.034 13.5 0.1 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 CEP11573.1 - 0.044 14.0 0.1 0.6 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 CEP11573.1 - 0.058 13.3 0.1 0.28 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) CARD PF00619.16 CEP11573.1 - 0.079 12.8 0.3 0.23 11.2 0.2 1.8 1 0 0 1 1 1 0 Caspase recruitment domain AAA_25 PF13481.1 CEP11573.1 - 0.08 12.3 0.9 0.21 10.9 0.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CEP11573.1 - 0.1 12.5 0.4 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEP11573.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sec7 PF01369.15 CEP11573.1 - 0.11 12.1 1.6 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Sec7 domain cNMP_binding PF00027.24 CEP11574.1 - 1.9e-41 139.7 0.0 1.7e-20 72.5 0.0 5.4 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.17 CEP11574.1 - 1.1e-17 64.6 5.1 8.3e-17 61.7 3.6 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase zf-C2H2_6 PF13912.1 CEP11575.1 - 0.0034 17.2 1.4 0.0072 16.1 1.0 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CEP11575.1 - 0.17 12.2 2.8 0.31 11.4 1.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP11575.1 - 0.62 10.5 7.8 0.15 12.4 1.2 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type ABC_tran PF00005.22 CEP11576.1 - 3.3e-15 56.5 0.0 6.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CEP11576.1 - 1.6e-09 38.1 2.5 0.0013 18.7 0.2 2.8 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.1 CEP11576.1 - 4e-05 22.8 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain PduV-EutP PF10662.4 CEP11576.1 - 0.012 15.1 0.0 0.064 12.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CEP11576.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CEP11576.1 - 0.027 13.8 0.1 0.06 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CEP11576.1 - 0.029 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CEP11576.1 - 0.043 13.7 0.1 0.087 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CEP11576.1 - 0.047 14.0 0.2 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 CEP11576.1 - 0.06 10.6 0.5 0.083 10.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_17 PF13207.1 CEP11576.1 - 0.062 14.1 0.5 0.22 12.3 0.1 2.3 2 1 0 2 2 1 0 AAA domain NACHT PF05729.7 CEP11576.1 - 0.071 12.7 0.1 0.21 11.2 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CEP11576.1 - 0.089 12.7 0.1 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 CEP11576.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 CEP11576.1 - 0.12 11.6 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_33 PF13671.1 CEP11576.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CEP11576.1 - 0.18 11.9 0.6 1.1 9.3 0.4 2.2 1 1 0 1 1 1 0 AAA domain Ribosomal_S5_C PF03719.10 CEP11577.1 - 2.9e-24 84.1 0.0 3e-23 80.8 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CEP11577.1 - 3.1e-16 58.8 1.0 5.6e-16 58.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Fer4 PF00037.22 CEP11578.1 - 2.4e-15 55.3 15.2 4.9e-09 35.4 3.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 CEP11578.1 - 4.2e-13 49.4 10.9 6.8e-13 48.7 7.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 CEP11578.1 - 6.3e-11 41.9 4.3 3.9e-05 23.4 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 CEP11578.1 - 1.4e-10 41.7 6.7 3.2e-05 24.5 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 CEP11578.1 - 1.4e-10 40.7 23.2 2.3e-08 33.6 9.1 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CEP11578.1 - 6e-10 39.2 11.1 1.1e-09 38.3 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CEP11578.1 - 4.3e-09 35.7 13.2 5.2e-05 22.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 CEP11578.1 - 5.3e-09 35.9 30.5 3e-06 27.1 8.0 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 CEP11578.1 - 5.1e-08 32.4 17.5 0.00055 19.7 3.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 CEP11578.1 - 9.5e-07 28.6 12.3 0.00071 19.7 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 CEP11578.1 - 5.3e-06 26.6 10.7 0.00012 22.3 7.9 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.1 CEP11578.1 - 1.2e-05 25.5 10.4 0.0052 17.1 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 CEP11578.1 - 1.3e-05 25.5 10.4 0.013 15.9 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 CEP11578.1 - 0.00096 19.6 12.6 0.13 12.8 2.3 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 CEP11578.1 - 0.0036 17.7 18.6 0.0078 16.7 3.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 CEP11578.1 - 0.16 12.1 5.0 0.28 11.3 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Ribonucleas_3_3 PF14622.1 CEP11579.1 - 2.5e-22 79.2 0.6 3.2e-22 78.8 0.4 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CEP11579.1 - 0.0014 19.0 0.1 0.0023 18.3 0.1 1.4 1 1 0 1 1 1 1 Ribonuclease III domain DUF1702 PF08012.6 CEP11579.1 - 0.046 12.3 0.1 0.062 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) SWIRM PF04433.12 CEP11580.1 - 1.5e-32 111.5 4.6 2.3e-31 107.7 0.1 3.4 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-binding PF00249.26 CEP11580.1 - 4.2e-07 29.9 0.0 2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP11580.1 - 1.6e-05 24.8 0.2 0.00011 22.1 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Hemocyanin_N PF03722.9 CEP11580.1 - 0.015 15.4 1.6 0.044 13.9 0.2 2.5 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain FtsJ PF01728.14 CEP11581.1 - 2.7e-66 223.0 0.0 3.3e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CEP11581.1 - 0.0076 16.8 0.0 0.021 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CbiA PF01656.18 CEP11581.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SF3b10 PF07189.6 CEP11582.1 - 9.1e-37 124.7 0.0 1e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Fungal_trans PF04082.13 CEP11583.1 - 8.5e-24 83.8 0.8 8.5e-24 83.8 0.5 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP11583.1 - 6.7e-12 45.1 12.1 1.2e-11 44.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBS PF00571.23 CEP11584.1 - 3.9e-29 100.1 5.5 3.9e-08 32.9 0.1 4.5 4 0 0 4 4 4 4 CBS domain Peptidase_M48 PF01435.13 CEP11585.1 - 1.2e-41 142.7 0.0 1.4e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M13 PF01431.16 CEP11585.1 - 0.033 13.3 0.0 0.75 8.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M13 Transposase_21 PF02992.9 CEP11588.1 - 1.5e-09 37.3 0.0 3.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 GP41 PF00517.12 CEP11589.1 - 0.02 14.4 2.7 0.4 10.2 0.5 2.2 2 0 0 2 2 2 0 Retroviral envelope protein DUF2674 PF10879.3 CEP11589.1 - 0.035 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) CDO_I PF05995.7 CEP11589.1 - 0.048 12.8 0.1 10 5.2 0.0 2.5 2 0 0 2 2 2 0 Cysteine dioxygenase type I DUF4446 PF14584.1 CEP11589.1 - 0.15 11.8 1.1 2.2 8.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CENP-F_leu_zip PF10473.4 CEP11590.1 - 0.00078 19.3 3.9 0.0011 18.8 2.7 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.1 CEP11590.1 - 0.048 13.6 3.0 0.064 13.2 2.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 CEP11590.1 - 0.15 11.9 6.5 0.16 11.8 3.3 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 CEP11590.1 - 0.24 11.4 6.0 0.57 10.2 3.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CEP11590.1 - 0.29 10.6 3.6 0.42 10.1 2.5 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CEP11590.1 - 0.36 9.8 6.2 0.53 9.2 4.1 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF4078 PF13300.1 CEP11590.1 - 0.38 10.8 3.5 0.62 10.2 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) DUF641 PF04859.7 CEP11590.1 - 0.57 9.9 5.7 1.3 8.7 0.8 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Bacillus_HBL PF05791.6 CEP11590.1 - 1.3 8.3 6.1 11 5.3 4.2 2.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3886 PF13025.1 CEP11590.1 - 2.2 8.3 7.3 5.5 7.0 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) DUF2992 PF11208.3 CEP11590.1 - 2.4 8.0 7.7 0.37 10.7 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) GCR1_C PF12550.3 CEP11593.1 - 2.6e-18 65.6 0.1 5e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Med8 PF10232.4 CEP11593.1 - 0.018 14.5 0.2 0.034 13.6 0.2 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF2051 PF09738.4 CEP11593.1 - 0.095 11.9 0.2 0.095 11.9 0.2 1.9 1 1 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) DUF1311 PF07007.7 CEP11593.1 - 0.21 11.6 2.9 0.41 10.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) PDGF PF00341.12 CEP11594.1 - 0.09 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 PDGF/VEGF domain Nucleoplasmin PF03066.10 CEP11595.1 - 0.042 13.3 0.6 0.06 12.8 0.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin DDE_3 PF13358.1 CEP11596.1 - 2.3e-12 46.8 0.0 3.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Spt20 PF12090.3 CEP11597.1 - 0.0089 15.3 2.5 0.009 15.3 1.7 1.2 1 0 0 1 1 1 1 Spt20 family Band_3_cyto PF07565.8 CEP11597.1 - 0.043 13.3 0.6 0.041 13.4 0.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain OTU PF02338.14 CEP11597.1 - 0.055 14.0 0.0 0.055 14.0 0.0 2.0 2 0 0 2 2 2 0 OTU-like cysteine protease TUSC2 PF15000.1 CEP11597.1 - 0.2 11.7 2.4 0.29 11.2 1.7 1.3 1 0 0 1 1 1 0 Tumour suppressor candidate 2 CxxCxxCC PF03692.10 CEP11597.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.2 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain RAB3GAP2_N PF14655.1 CEP11597.1 - 1.7 7.5 9.5 2.2 7.2 6.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pex16 PF08610.5 CEP11597.1 - 3.6 6.4 6.8 4.3 6.2 4.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RED_N PF07808.8 CEP11597.1 - 5.1 6.2 12.8 6.2 5.9 8.8 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Phosducin PF02114.11 CEP11597.1 - 9.3 4.8 8.0 3.8 6.1 4.1 1.4 2 0 0 2 2 2 0 Phosducin APC_CDC26 PF10471.4 CEP11597.1 - 9.4 7.0 21.2 16 6.3 14.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 RVT_1 PF00078.22 CEP11598.1 - 0.0019 17.6 0.2 0.0027 17.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP11599.1 - 3.1e-10 39.7 0.1 1.3e-09 37.7 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2414 PF10309.4 CEP11600.1 - 0.00095 18.8 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 CEP11600.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain PH PF00169.24 CEP11601.1 - 4.2e-10 39.7 0.1 4e-06 26.9 0.0 2.9 2 1 0 2 2 2 2 PH domain PH_9 PF15410.1 CEP11601.1 - 0.00014 21.9 0.1 0.01 16.0 0.0 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain RXT2_N PF08595.6 CEP11601.1 - 7.9 6.2 14.6 1.6 8.5 1.9 3.3 3 0 0 3 3 3 0 RXT2-like, N-terminal Vac_Fusion PF02346.11 CEP11602.1 - 0.056 12.8 8.7 0.15 11.4 0.7 3.4 2 1 1 3 3 3 0 Chordopoxvirus fusion protein WEMBL PF05701.6 CEP11602.1 - 1.6 7.0 53.7 0.32 9.4 25.9 2.5 1 1 1 2 2 2 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 CEP11602.1 - 4.3 7.0 58.9 0.06 13.0 15.1 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.6 CEP11602.1 - 9.1 4.6 42.9 2.2 6.6 17.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HARE-HTH PF05066.8 CEP11603.1 - 1.6e-05 25.1 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Metallophos PF00149.23 CEP11604.1 - 2.8e-20 72.5 0.5 5.3e-20 71.6 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP11604.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_C PF14008.1 CEP11604.1 - 0.00015 21.8 0.8 0.00092 19.2 0.1 2.7 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C RabGAP-TBC PF00566.13 CEP11606.1 - 5.2e-46 156.8 0.1 1.1e-45 155.8 0.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 CEP11606.1 - 4.5e-26 91.5 0.0 8e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11606.1 - 8.9e-16 57.7 0.0 1.8e-15 56.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.15 CEP11606.1 - 4.1e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain SYF2 PF08231.7 CEP11607.1 - 8.8e-39 133.0 15.2 8.8e-39 133.0 10.5 2.2 2 0 0 2 2 2 1 SYF2 splicing factor LRR_6 PF13516.1 CEP11607.1 - 0.0028 17.5 1.0 0.57 10.4 0.2 3.4 2 1 0 2 2 2 1 Leucine Rich repeat IpgD PF05925.7 CEP11607.1 - 0.0037 15.5 1.1 0.0053 15.0 0.7 1.3 1 0 0 1 1 1 1 Enterobacterial virulence protein IpgD F-box-like PF12937.2 CEP11607.1 - 0.099 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like CDC37_M PF08565.6 CEP11608.1 - 2.7e-35 121.3 2.3 2.7e-35 121.3 1.6 2.6 1 1 1 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.9 CEP11608.1 - 6e-34 117.8 13.0 6e-34 117.8 9.0 2.5 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_C PF08564.5 CEP11608.1 - 2.1e-15 56.3 0.3 2.1e-15 56.3 0.2 2.9 2 1 0 2 2 2 1 Cdc37 C terminal domain NPV_P10 PF05531.7 CEP11608.1 - 0.17 12.1 7.1 1.6 9.0 0.8 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Ras PF00071.17 CEP11609.1 - 1.9e-42 144.4 0.1 3.3e-42 143.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP11609.1 - 3e-18 66.4 0.1 1e-17 64.7 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP11609.1 - 6.1e-09 35.3 0.0 9.6e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP11609.1 - 2e-06 27.3 0.0 6.1e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP11609.1 - 8.1e-05 22.5 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PGAP1 PF07819.8 CEP11609.1 - 0.00073 19.1 0.0 0.0018 17.8 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CEP11609.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) FeoB_N PF02421.13 CEP11609.1 - 0.0023 17.2 0.0 0.008 15.4 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 CEP11609.1 - 0.0065 16.3 0.0 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 CEP11609.1 - 0.0084 16.0 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP11609.1 - 0.033 13.9 1.3 0.27 10.9 1.3 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 CEP11609.1 - 0.037 13.6 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) SRPRB PF09439.5 CEP11609.1 - 0.047 12.9 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2305 PF10230.4 CEP11609.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Arch_ATPase PF01637.13 CEP11609.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase GMC_oxred_N PF00732.14 CEP11610.1 - 2.5e-51 174.6 0.1 3.8e-51 173.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEP11610.1 - 9.7e-24 84.2 0.0 2.1e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CEP11610.1 - 1.3e-09 37.4 3.0 1.6e-05 23.9 2.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 CEP11610.1 - 2.7e-08 33.1 1.9 0.00017 20.6 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEP11610.1 - 5.3e-05 23.1 0.8 0.00093 19.1 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEP11610.1 - 8.9e-05 21.1 2.2 0.0035 15.8 0.9 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 CEP11610.1 - 0.0009 19.2 2.4 0.0022 17.9 1.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CEP11610.1 - 0.0016 17.5 0.9 0.02 14.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 CEP11610.1 - 0.0022 17.1 0.5 0.0035 16.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.13 CEP11610.1 - 0.0024 16.2 0.0 0.0042 15.4 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor ApbA PF02558.11 CEP11610.1 - 0.0026 17.2 0.1 0.0057 16.0 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 CEP11610.1 - 0.0077 15.1 0.1 0.042 12.7 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Cohesin_load PF10345.4 CEP11610.1 - 0.04 12.1 0.1 0.056 11.6 0.0 1.1 1 0 0 1 1 1 0 Cohesin loading factor GIDA PF01134.17 CEP11610.1 - 0.057 12.2 1.3 0.17 10.7 0.5 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 CEP11610.1 - 0.27 11.6 2.3 0.67 10.4 1.0 2.2 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP11610.1 - 0.28 10.2 4.8 0.48 9.4 3.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FHA PF00498.21 CEP11611.1 - 3.1e-07 30.3 0.2 1.9e-06 27.8 0.0 2.4 3 0 0 3 3 3 1 FHA domain DUF869 PF05911.6 CEP11612.1 - 0.0099 14.1 2.5 0.012 13.9 1.7 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF4441 PF14536.1 CEP11612.1 - 0.058 13.3 2.5 0.076 12.9 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) ArsR PF09824.4 CEP11612.1 - 0.085 12.1 0.2 0.11 11.8 0.1 1.3 1 1 0 1 1 1 0 ArsR transcriptional regulator rve PF00665.21 CEP11613.1 - 6.4e-16 58.5 0.0 9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP11613.1 - 0.0005 19.4 1.7 0.00094 18.5 1.2 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Helitron_like_N PF14214.1 CEP11614.1 - 5.5e-46 156.6 0.0 7.1e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 CEP11614.1 - 0.027 13.2 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF3296 PF11726.3 CEP11614.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) HTH_29 PF13551.1 CEP11615.1 - 4.1e-06 26.9 0.1 1.9e-05 24.7 0.0 2.0 1 1 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 CEP11615.1 - 4.9e-06 26.0 0.1 1.3e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP11615.1 - 0.001 19.0 0.0 0.0031 17.4 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain DDE_3 PF13358.1 CEP11615.1 - 0.0018 17.9 0.0 0.0084 15.8 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease NEP PF10167.4 CEP11615.1 - 0.022 14.4 0.1 0.075 12.7 0.0 1.9 2 1 0 2 2 2 0 Uncharacterised conserved protein LZ_Tnp_IS481 PF13011.1 CEP11615.1 - 0.15 12.4 0.4 0.45 10.8 0.0 2.0 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 DDE_3 PF13358.1 CEP11617.1 - 7.9e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L31e PF01198.14 CEP11617.1 - 0.039 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31e THDPS_M PF14789.1 CEP11617.1 - 0.074 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle RVT_1 PF00078.22 CEP11618.1 - 1e-05 25.0 0.0 1.1e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4162 PF13732.1 CEP11619.1 - 0.084 13.3 0.2 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Zip PF02535.17 CEP11621.1 - 3.1 6.7 7.4 4.4 6.2 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SMN PF06003.7 CEP11622.1 - 0.66 9.0 5.1 0.091 11.8 0.5 1.6 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) R3H PF01424.17 CEP11623.1 - 4.5e-11 42.2 0.0 8.3e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 CEP11623.1 - 8.1e-08 32.0 200.8 0.00094 19.0 12.0 14.5 12 1 1 13 13 13 9 NF-X1 type zinc finger DUF4437 PF14499.1 CEP11625.1 - 0.0065 15.4 0.0 0.0086 15.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) MutS_V PF00488.16 CEP11626.1 - 1.2e-89 299.7 0.0 2.1e-89 298.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CEP11626.1 - 8.4e-41 139.9 0.2 1.7e-40 139.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CEP11626.1 - 1.2e-26 92.9 4.8 5.2e-18 65.1 0.1 2.9 3 0 0 3 3 3 2 MutS domain I MutS_II PF05188.12 CEP11626.1 - 7.7e-14 51.9 0.0 1.9e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CEP11626.1 - 8.6e-10 38.6 0.0 3.3e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV Lipase_3 PF01764.20 CEP11627.1 - 1.3e-19 70.2 0.0 5.9e-19 68.0 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) DDE_3 PF13358.1 CEP11627.1 - 5.9e-14 52.0 0.0 1.3e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP11627.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP11627.1 - 0.025 14.2 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Abhydrolase_1 PF00561.15 CEP11627.1 - 0.062 12.8 0.3 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEP11627.1 - 0.073 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_8 PF01270.12 CEP11628.1 - 9.9e-44 149.4 0.0 1.2e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 Pex14_N PF04695.8 CEP11629.1 - 6.1e-16 58.7 0.7 6.1e-16 58.7 0.5 2.4 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 CEP11629.1 - 0.022 14.6 0.3 0.022 14.6 0.2 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Metallophos PF00149.23 CEP11630.1 - 8.8e-39 132.9 0.5 1.6e-38 132.1 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cation_efflux PF01545.16 CEP11630.1 - 2.3e-38 131.9 14.8 7.7e-36 123.6 5.7 2.2 1 1 1 2 2 2 2 Cation efflux family MCPVI PF02993.9 CEP11630.1 - 0.097 12.8 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Minor capsid protein VI LRR_4 PF12799.2 CEP11631.1 - 1.2e-08 34.3 3.6 6.2e-05 22.5 2.0 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) PHD PF00628.24 CEP11631.1 - 5.4e-06 25.9 10.6 9.7e-06 25.1 7.3 1.4 1 0 0 1 1 1 1 PHD-finger LRR_7 PF13504.1 CEP11631.1 - 0.0022 17.9 0.4 15 6.3 0.0 4.2 3 0 0 3 3 3 1 Leucine rich repeat NTF2 PF02136.15 CEP11631.1 - 0.0037 17.6 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 CEP11631.1 - 0.0057 16.3 3.7 0.13 12.0 0.9 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 CEP11631.1 - 0.0077 15.8 0.1 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 CEP11631.1 - 0.023 14.7 4.8 1.7 8.9 0.3 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 CEP11631.1 - 0.06 13.4 1.1 2.7 8.3 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat PHD_2 PF13831.1 CEP11631.1 - 0.44 9.8 5.4 1.5 8.2 3.8 1.9 1 1 0 1 1 1 0 PHD-finger DUF3808 PF10300.4 CEP11632.1 - 7.1e-64 216.0 8.4 9.9e-64 215.6 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 CEP11632.1 - 0.37 10.4 6.4 3.9 7.1 0.2 3.7 4 0 0 4 4 4 0 TPR repeat KOW PF00467.24 CEP11633.1 - 1.1e-10 40.7 3.1 1.1e-10 40.7 2.2 2.0 2 0 0 2 2 2 1 KOW motif DUF1442 PF07279.6 CEP11633.1 - 0.0083 15.2 1.4 0.01 14.9 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Ribosomal_L32p PF01783.18 CEP11633.1 - 5 7.3 6.3 6.4 7.0 3.0 2.1 2 0 0 2 2 2 0 Ribosomal L32p protein family tRNA_U5-meth_tr PF05958.6 CEP11635.1 - 9.1e-15 54.1 1.0 1.4e-13 50.2 0.7 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CEP11635.1 - 3.5e-11 42.9 0.2 1e-10 41.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CEP11635.1 - 2.9e-08 33.2 0.2 6.1e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 CEP11635.1 - 5.9e-07 29.1 0.3 1.7e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 CEP11635.1 - 1.6e-06 28.6 0.1 1.4e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP11635.1 - 2.4e-06 27.5 0.0 6.6e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CEP11635.1 - 6.2e-06 25.7 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 CEP11635.1 - 0.00026 20.2 1.7 0.00049 19.3 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 CEP11635.1 - 0.00051 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 CEP11635.1 - 0.0014 18.2 0.2 0.0034 16.9 0.2 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 CEP11635.1 - 0.0015 18.1 0.2 0.0033 17.0 0.1 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.12 CEP11635.1 - 0.0019 17.2 0.1 0.0041 16.2 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 CEP11635.1 - 0.0021 18.3 0.1 0.0067 16.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP11635.1 - 0.024 13.7 0.2 0.042 12.9 0.1 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RRM_1 PF00076.17 CEP11635.1 - 0.037 13.6 0.0 0.093 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DREV PF05219.7 CEP11635.1 - 0.045 12.6 0.0 0.095 11.5 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase RRM_5 PF13893.1 CEP11635.1 - 0.059 13.2 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP11635.1 - 0.082 12.8 0.0 0.31 11.0 0.0 2.1 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 CEP11635.1 - 0.084 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DXP_redisom_C PF08436.7 CEP11635.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Methyltransf_12 PF08242.7 CEP11635.1 - 0.095 13.1 0.1 0.3 11.5 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain ATP_bind_1 PF03029.12 CEP11636.1 - 6.3e-84 281.2 0.2 2.7e-82 275.8 0.2 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 CEP11636.1 - 3.8e-05 23.1 0.2 0.00018 20.9 0.0 2.1 1 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SPT6_acidic PF14632.1 CEP11636.1 - 0.01 15.9 3.4 0.02 15.0 2.3 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 AAA_17 PF13207.1 CEP11636.1 - 0.022 15.5 3.8 0.17 12.7 2.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CEP11636.1 - 0.041 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 CEP11636.1 - 0.07 11.8 0.4 0.2 10.3 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_24 PF13479.1 CEP11636.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CEP11636.1 - 0.14 11.5 0.1 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Fucose_iso_N2 PF07882.7 CEP11636.1 - 0.2 11.3 1.3 0.38 10.4 0.0 2.1 3 0 0 3 3 3 0 L-fucose isomerase, second N-terminal domain zf-U1 PF06220.7 CEP11636.1 - 0.25 10.9 1.2 0.4 10.2 0.1 1.9 2 0 0 2 2 2 0 U1 zinc finger Hepatitis_core PF00906.15 CEP11636.1 - 0.36 10.4 1.7 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Hepatitis core antigen DUF1682 PF07946.9 CEP11636.1 - 1.7 7.4 5.2 3.2 6.4 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) F-box-like PF12937.2 CEP11638.1 - 5.4e-08 32.4 0.8 1.1e-07 31.4 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP11638.1 - 0.00035 20.1 0.9 0.0015 18.1 0.6 2.1 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.2 CEP11638.1 - 0.051 13.2 0.6 7.1 6.3 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LIM PF00412.17 CEP11640.1 - 2.2e-51 171.7 42.9 1.1e-14 54.1 1.3 4.3 4 0 0 4 4 4 4 LIM domain CytochromB561_N PF09786.4 CEP11640.1 - 0.13 10.7 0.4 0.17 10.2 0.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MRI PF15325.1 CEP11640.1 - 0.53 11.2 4.4 0.78 10.7 0.6 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF3725 PF12523.3 CEP11640.1 - 3.8 7.6 8.8 23 5.1 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3725) AMP-binding PF00501.23 CEP11641.1 - 4.3e-96 321.8 0.0 5.7e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP11641.1 - 0.073 14.0 0.1 0.17 12.8 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 CEP11642.1 - 4.4e-62 209.5 0.0 1.2e-61 208.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain DEAD PF00270.24 CEP11642.1 - 2.7e-46 157.1 0.0 9.8e-46 155.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pkinase_Tyr PF07714.12 CEP11642.1 - 3.8e-39 134.3 0.0 7.8e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Helicase_C PF00271.26 CEP11642.1 - 5e-24 83.9 0.0 1.4e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Kinase-like PF14531.1 CEP11642.1 - 2.1e-08 33.5 0.0 2.1e-08 33.5 0.0 2.0 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.6 CEP11642.1 - 0.027 13.3 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Methyltransf_16 PF10294.4 CEP11643.1 - 1.9e-16 60.0 0.0 2.5e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 CEP11643.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2410 PF10307.4 CEP11644.1 - 6.4e-30 104.0 0.1 2e-29 102.3 0.0 1.8 1 1 0 1 1 1 1 Hypothetical protein (DUF2410) Pkinase PF00069.20 CEP11645.1 - 3.8e-50 170.4 0.0 1e-43 149.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11645.1 - 5.4e-16 58.4 0.2 1.9e-12 46.8 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEP11645.1 - 9.5e-07 28.0 0.0 1.3e-05 24.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CEP11645.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP11645.1 - 0.014 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Transposase_31 PF04754.7 CEP11646.1 - 6e-07 29.0 0.1 1.2e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Putative transposase, YhgA-like DUF2887 PF11103.3 CEP11646.1 - 0.0088 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2887) WD40 PF00400.27 CEP11647.1 - 2.3e-12 46.2 0.6 2.2e-07 30.5 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Pico_P2A PF00947.14 CEP11649.1 - 0.026 14.3 0.1 0.047 13.5 0.1 1.6 1 1 0 1 1 1 0 Picornavirus core protein 2A HTH_Tnp_Tc3_2 PF01498.13 CEP11650.1 - 2.1e-15 56.5 0.6 4.6e-15 55.4 0.4 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP11650.1 - 1e-05 25.6 0.1 1.6e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 CEP11650.1 - 0.0001 22.0 1.7 0.02 14.7 0.1 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 CEP11650.1 - 0.0044 17.7 0.1 0.012 16.4 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.1 CEP11650.1 - 0.006 16.1 0.8 0.017 14.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP11650.1 - 0.11 12.2 0.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.1 CEP11650.1 - 0.11 12.5 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain ATG11 PF10377.4 CEP11651.1 - 8e-21 74.2 0.2 8e-21 74.2 0.2 3.0 3 0 0 3 3 3 1 Autophagy-related protein 11 RNase_T PF00929.19 CEP11651.1 - 3.5e-13 50.1 1.1 1e-12 48.6 0.0 2.5 2 1 1 3 3 3 1 Exonuclease Rep_fac_C PF08542.6 CEP11652.1 - 1e-18 67.0 0.0 2.4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 CEP11652.1 - 5.4e-18 65.4 0.0 1.1e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CEP11652.1 - 3.2e-16 59.3 0.3 1.3e-13 50.9 0.0 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CEP11652.1 - 5.2e-10 38.6 0.0 5e-08 32.0 0.0 2.5 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CEP11652.1 - 1.1e-07 32.0 0.6 0.0035 17.4 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.1 CEP11652.1 - 2.2e-07 30.7 0.1 7.6e-07 29.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CEP11652.1 - 1.6e-06 27.3 0.0 3.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CEP11652.1 - 7.2e-06 25.6 0.0 2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CEP11652.1 - 2.8e-05 24.2 0.0 0.00018 21.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 CEP11652.1 - 6e-05 22.7 0.1 0.00013 21.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 CEP11652.1 - 7.4e-05 22.3 0.3 0.00084 18.8 0.1 2.5 3 0 0 3 3 3 1 DNA polymerase III, delta subunit DUF815 PF05673.8 CEP11652.1 - 0.0003 19.8 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DEAD PF00270.24 CEP11652.1 - 0.001 18.6 0.1 0.035 13.6 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.1 CEP11652.1 - 0.0016 18.0 0.6 0.037 13.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CEP11652.1 - 0.0028 17.2 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CEP11652.1 - 0.0032 16.8 0.2 0.022 14.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CEP11652.1 - 0.0032 17.0 0.2 0.0083 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEP11652.1 - 0.0032 17.1 0.3 0.02 14.5 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CEP11652.1 - 0.0037 17.5 0.0 0.0079 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CEP11652.1 - 0.004 16.6 0.2 1 8.7 0.0 2.6 2 1 1 3 3 3 1 AAA-like domain ResIII PF04851.10 CEP11652.1 - 0.0046 16.8 0.0 0.013 15.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.1 CEP11652.1 - 0.005 17.6 0.0 0.013 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CEP11652.1 - 0.0054 15.6 0.0 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 CEP11652.1 - 0.0077 16.1 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CEP11652.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 CEP11652.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 CEP11652.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 CEP11652.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 CEP11652.1 - 0.034 13.3 0.1 0.35 9.9 0.0 2.2 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CEP11652.1 - 0.038 13.2 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein TPR_6 PF13174.1 CEP11652.1 - 0.06 13.8 1.1 4.4 7.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FtsK_SpoIIIE PF01580.13 CEP11652.1 - 0.064 12.7 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family zf-DNA_Pol PF08996.5 CEP11652.1 - 0.069 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger AAA_23 PF13476.1 CEP11652.1 - 0.08 13.2 1.7 0.32 11.2 1.1 2.1 1 1 0 1 1 1 0 AAA domain BrkDBD PF09607.5 CEP11652.1 - 0.085 12.4 0.1 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 Brinker DNA-binding domain NTPase_1 PF03266.10 CEP11652.1 - 0.088 12.5 0.2 0.85 9.3 0.0 2.3 1 1 0 2 2 2 0 NTPase SNF2_N PF00176.18 CEP11652.1 - 0.098 11.4 0.1 0.69 8.6 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_29 PF13555.1 CEP11652.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain MobB PF03205.9 CEP11652.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CEP11652.1 - 0.15 12.2 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase GATA PF00320.22 CEP11653.1 - 1.6e-14 52.9 7.2 4.1e-14 51.6 5.0 1.7 1 0 0 1 1 1 1 GATA zinc finger Ras PF00071.17 CEP11654.1 - 9.5e-49 164.8 1.2 1.2e-48 164.5 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP11654.1 - 5.6e-13 49.4 0.1 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP11654.1 - 2.1e-07 30.3 0.1 2.9e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP11654.1 - 0.00012 21.5 0.1 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CEP11654.1 - 0.0016 18.0 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Gemini_AL3 PF01407.12 CEP11654.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Geminivirus AL3 protein YhzD PF14120.1 CEP11654.1 - 0.096 12.5 0.1 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 YhzD-like protein V-set_CD47 PF08204.6 CEP11655.1 - 3.2 7.5 8.1 4.8 6.9 0.3 2.4 1 1 1 2 2 2 0 CD47 immunoglobulin-like domain Pro_isomerase PF00160.16 CEP11656.1 - 1.4e-40 139.0 0.3 3.4e-40 137.7 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.18 CEP11657.1 - 1.1e-16 59.9 0.1 1.9e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CEP11657.1 - 1.9e-05 24.2 2.2 2e-05 24.1 0.5 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEP11657.1 - 0.00015 21.9 0.1 0.00015 21.9 0.1 2.3 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEP11657.1 - 0.0066 16.3 0.0 0.022 14.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LRR_6 PF13516.1 CEP11658.1 - 0.43 10.7 5.6 2.6 8.4 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.2 CEP11658.1 - 3.9 7.2 13.7 23 4.7 1.4 5.1 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CEP11658.1 - 4.1 8.0 7.5 13 6.5 0.1 5.0 6 0 0 6 6 6 0 Leucine rich repeat APH PF01636.18 CEP11659.1 - 6.1e-40 137.4 0.0 9.6e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CEP11659.1 - 2.7e-05 23.4 0.0 9.5e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase CGI-121 PF08617.5 CEP11660.1 - 2.7e-36 124.6 0.6 3.1e-36 124.5 0.4 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF3246 PF11596.3 CEP11661.1 - 0.034 13.4 0.3 0.038 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Nucleo_P87 PF07267.6 CEP11661.1 - 0.27 9.8 2.6 0.33 9.5 1.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-C2H2 PF00096.21 CEP11661.1 - 0.6 10.5 3.6 1.3 9.5 2.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sds3 PF08598.6 CEP11662.1 - 6e-17 61.8 19.2 6e-17 61.8 13.3 1.9 2 1 0 2 2 2 1 Sds3-like HAD PF12710.2 CEP11662.1 - 3e-10 40.6 2.1 5e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP11662.1 - 1.1e-05 25.7 2.2 4.6e-05 23.7 0.1 2.9 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP11662.1 - 0.00014 22.3 0.0 0.00058 20.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2783 PF10932.3 CEP11662.1 - 0.034 13.6 0.4 0.1 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) DUF4210 PF13915.1 CEP11664.1 - 1.1e-18 67.2 0.1 2.2e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 CEP11664.1 - 5e-17 61.5 0.1 1.3e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis Arf PF00025.16 CEP11664.1 - 3.5e-13 49.1 0.4 8.6e-13 47.8 0.3 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Fer2_3 PF13085.1 CEP11665.1 - 3.2e-32 110.6 0.0 5.1e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CEP11665.1 - 2.3e-10 40.6 8.2 2.3e-10 40.6 5.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CEP11665.1 - 2.7e-08 33.6 5.9 2.7e-08 33.6 4.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CEP11665.1 - 6.5e-05 23.2 8.3 9e-05 22.8 2.3 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CEP11665.1 - 0.00015 21.9 6.2 0.042 14.1 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CEP11665.1 - 0.00015 21.4 5.6 0.00015 21.4 3.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CEP11665.1 - 0.00083 19.6 5.5 0.00083 19.6 3.8 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CEP11665.1 - 0.0011 18.7 2.3 0.0096 15.6 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.3 CEP11665.1 - 0.087 13.2 0.7 0.18 12.2 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 CEP11665.1 - 7.2 7.2 8.2 1.4 9.4 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S single cluster domain Myc_N PF01056.13 CEP11667.1 - 0.00074 18.7 1.5 0.00095 18.4 1.1 1.0 1 0 0 1 1 1 1 Myc amino-terminal region CAF1A PF12253.3 CEP11668.1 - 0.66 10.1 12.0 0.75 9.9 8.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Myc_N PF01056.13 CEP11668.1 - 0.69 9.0 5.8 0.7 8.9 4.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TFIIA PF03153.8 CEP11668.1 - 0.93 9.3 9.0 0.88 9.3 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 CEP11668.1 - 1.1 8.7 10.5 1.2 8.6 7.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 CEP11668.1 - 1.3 7.4 9.0 1.2 7.5 6.2 1.0 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 CEP11668.1 - 1.4 6.6 5.8 1.2 6.9 4.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 CEP11668.1 - 3 5.8 6.6 3 5.8 4.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 F-box-like PF12937.2 CEP11669.1 - 2.1e-07 30.5 0.1 4.2e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP11669.1 - 0.00051 19.6 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 CEP11671.1 - 7.8e-19 66.7 13.1 0.0012 18.6 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CEP11671.1 - 0.037 13.5 0.8 1.3 8.6 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Epimerase PF01370.16 CEP11672.1 - 1.2e-53 182.0 0.0 1.9e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CEP11672.1 - 4.5e-28 96.9 0.8 8.9e-28 96.0 0.6 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Pkinase PF00069.20 CEP11672.1 - 4.4e-22 78.4 1.7 8.5e-22 77.5 0.0 2.0 2 0 0 2 2 1 1 Protein kinase domain 3Beta_HSD PF01073.14 CEP11672.1 - 1.9e-18 66.1 0.0 1.7e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CEP11672.1 - 4e-15 55.4 1.8 8.8e-15 54.3 0.0 2.3 2 1 0 2 2 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 CEP11672.1 - 1.2e-12 47.3 1.7 1.4e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 CEP11672.1 - 8.7e-12 45.2 0.0 1.7e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CEP11672.1 - 8.3e-10 38.0 0.0 8.3e-10 38.0 0.0 1.9 2 1 0 2 2 1 1 Male sterility protein NAD_binding_10 PF13460.1 CEP11672.1 - 2.4e-09 37.4 0.0 5.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CEP11672.1 - 4.4e-08 32.9 0.0 9.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CEP11672.1 - 7.3e-05 22.1 0.0 0.0004 19.7 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Suf PF05843.9 CEP11672.1 - 0.0061 16.3 6.3 0.01 15.5 4.4 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) UDPG_MGDP_dh_N PF03721.9 CEP11672.1 - 0.097 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CEP11672.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RR_TM4-6 PF06459.7 CEP11672.1 - 0.88 9.4 6.2 1.5 8.6 4.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CEP11672.1 - 4.1 6.3 4.5 6.4 5.6 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.8 CEP11672.1 - 5.1 6.5 9.7 9.1 5.7 6.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 CEP11672.1 - 5.8 6.9 17.6 12 5.8 12.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AMP-binding PF00501.23 CEP11673.1 - 2.3e-98 329.3 0.2 2.8e-98 329.0 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP11673.1 - 4.3e-18 66.0 0.0 1.3e-17 64.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YjeF_N PF03853.10 CEP11674.1 - 4.6e-42 143.4 0.0 5.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus NPCBM_assoc PF10633.4 CEP11674.1 - 0.056 13.4 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase bZIP_1 PF00170.16 CEP11675.1 - 4.9e-09 36.0 9.9 4.9e-09 36.0 6.9 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP11675.1 - 1.1e-07 31.5 11.4 3.3e-07 30.0 7.9 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CEP11675.1 - 0.00017 21.7 10.0 0.00072 19.8 7.0 2.0 1 0 0 1 1 1 1 bZIP Maf transcription factor CCDC92 PF14916.1 CEP11675.1 - 0.0008 18.9 0.2 0.0027 17.2 0.1 1.9 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Herpes_UL6 PF01763.11 CEP11675.1 - 0.00084 17.6 4.7 0.0014 16.9 3.3 1.3 1 0 0 1 1 1 1 Herpesvirus UL6 like Phage_lysis PF03245.8 CEP11675.1 - 0.0049 16.8 1.5 0.017 15.1 1.0 2.0 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein CENP-H PF05837.7 CEP11675.1 - 0.006 16.7 1.3 0.032 14.4 0.9 2.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Fib_alpha PF08702.5 CEP11675.1 - 0.15 12.1 8.9 5.5 7.1 4.8 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TSC22 PF01166.13 CEP11675.1 - 0.16 11.9 5.7 0.12 12.3 1.8 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family IncA PF04156.9 CEP11675.1 - 0.58 9.7 9.5 0.048 13.2 2.5 2.2 2 0 0 2 2 2 0 IncA protein Ribosomal_S25 PF03297.10 CEP11676.1 - 3.2e-42 142.8 2.8 3.9e-42 142.5 1.9 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 CEP11676.1 - 0.0082 15.5 0.5 0.012 14.9 0.3 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding BioT2 PF15368.1 CEP11676.1 - 0.01 15.5 0.6 0.018 14.8 0.3 1.3 1 1 0 1 1 1 0 Spermatogenesis family BioT2 RNA_pol_Rpc34 PF05158.7 CEP11676.1 - 0.016 14.4 0.1 0.018 14.2 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit MarR_2 PF12802.2 CEP11676.1 - 0.037 13.6 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 MarR family BK_channel_a PF03493.13 CEP11677.1 - 3.6e-20 71.7 0.3 1.7e-18 66.4 0.0 3.4 4 0 0 4 4 4 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 CEP11677.1 - 6.7e-15 54.5 5.7 1.6e-14 53.3 4.0 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 CEP11677.1 - 0.01 15.0 9.7 0.021 14.0 6.7 1.5 1 0 0 1 1 1 0 Ion transport protein TrkA_N PF02254.13 CEP11677.1 - 0.013 15.5 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain CLTH PF10607.4 CEP11678.1 - 5.9e-25 87.6 5.7 2.2e-24 85.8 1.9 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 CEP11678.1 - 8.7e-25 87.2 0.5 1.5e-24 86.4 0.4 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 CEP11678.1 - 0.0006 19.4 0.1 0.0017 18.0 0.0 1.8 1 0 0 1 1 1 1 LisH DUF1839 PF08893.5 CEP11678.1 - 0.0032 16.4 0.4 0.0032 16.4 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1839) DUF2031 PF09592.5 CEP11678.1 - 0.065 12.3 0.3 0.065 12.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) DDE_3 PF13358.1 CEP11679.1 - 1.8e-13 50.4 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SRF-TF PF00319.13 CEP11679.1 - 0.033 13.4 0.1 0.033 13.4 0.1 2.2 3 0 0 3 3 3 0 SRF-type transcription factor (DNA-binding and dimerisation domain) HTH_33 PF13592.1 CEP11679.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix zf-C3HC4_2 PF13923.1 CEP11680.1 - 2.9e-08 33.5 8.6 2.9e-08 33.5 6.0 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP11680.1 - 5.4e-08 32.3 5.6 5.4e-08 32.3 3.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP11680.1 - 1e-07 31.4 8.0 1e-07 31.4 5.6 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP11680.1 - 3.8e-07 29.7 8.0 3.8e-07 29.7 5.6 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CEP11680.1 - 2.5e-06 27.2 7.1 2.5e-06 27.2 4.9 2.5 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 CEP11680.1 - 3.4e-06 27.0 6.0 1e-05 25.5 1.6 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 CEP11680.1 - 1.4e-05 24.7 2.7 3.7e-05 23.4 1.9 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein BRCT PF00533.21 CEP11680.1 - 7.8e-05 22.7 3.1 0.35 11.0 0.1 3.7 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4_4 PF15227.1 CEP11680.1 - 0.00021 21.0 8.2 0.00021 21.0 5.7 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CEP11680.1 - 0.001 18.6 6.0 0.001 18.6 4.2 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RanBP PF00641.13 CEP11680.1 - 0.0095 15.0 4.1 0.0095 15.0 2.8 2.7 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DZR PF12773.2 CEP11680.1 - 0.025 14.4 12.0 1.2 9.0 0.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-Apc11 PF12861.2 CEP11680.1 - 0.13 12.1 5.4 0.14 12.0 0.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-H2C2 PF09337.5 CEP11681.1 - 0.0082 15.5 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger PPP4R2 PF09184.6 CEP11682.1 - 9.8e-22 77.8 17.3 1.8e-21 76.9 12.0 1.5 1 1 0 1 1 1 1 PPP4R2 Skp1 PF01466.14 CEP11682.1 - 0.77 9.8 6.8 0.38 10.8 1.8 2.4 2 1 0 2 2 2 0 Skp1 family, dimerisation domain PTH2 PF01981.11 CEP11683.1 - 3.1e-46 155.8 0.0 9.1e-46 154.3 0.0 1.9 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Glyco_transf_8 PF01501.15 CEP11683.1 - 8.2e-32 110.4 0.6 4.5e-30 104.7 0.4 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CEP11683.1 - 0.00012 21.5 0.0 0.00044 19.6 0.0 2.0 1 0 0 1 1 1 1 Mannosyltransferase putative adh_short PF00106.20 CEP11684.1 - 1.7e-19 70.3 0.0 4.8e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP11684.1 - 9.4e-06 25.5 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP11684.1 - 2.9e-05 23.8 0.0 6.8e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CEP11684.1 - 0.0002 20.8 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family P-mevalo_kinase PF04275.9 CEP11684.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphomevalonate kinase Exo_endo_phos PF03372.18 CEP11686.1 - 0.024 14.5 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP11686.1 - 0.04 13.5 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Polysacc_deac_1 PF01522.16 CEP11688.1 - 1.1e-28 99.3 0.0 1.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP11688.1 - 2.4e-05 23.3 0.1 5.3e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.4 CEP11688.1 - 0.032 13.6 1.6 0.056 12.8 1.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.16 CEP11689.1 - 1.6e-28 98.7 0.1 4.5e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP11689.1 - 0.00035 19.5 0.0 0.00068 18.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Mnd1 PF03962.10 CEP11690.1 - 3.9e-55 186.4 12.3 4.6e-55 186.2 8.6 1.0 1 0 0 1 1 1 1 Mnd1 family Guanylate_cyc_2 PF09778.4 CEP11690.1 - 0.0027 16.9 0.2 0.0062 15.7 0.0 1.7 2 0 0 2 2 2 1 Guanylylate cyclase CaM_bdg_C0 PF10562.4 CEP11690.1 - 0.0041 16.9 0.5 0.0041 16.9 0.3 2.3 3 0 0 3 3 3 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit V_ATPase_I PF01496.14 CEP11690.1 - 0.21 9.4 5.2 0.21 9.3 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CEP11690.1 - 5.9 6.4 13.6 7.9 6.0 9.4 1.2 1 0 0 1 1 1 0 IncA protein DUF4168 PF13767.1 CEP11690.1 - 6.5 7.4 10.2 1.4e+02 3.1 7.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) Seryl_tRNA_N PF02403.17 CEP11690.1 - 8.2 6.5 15.9 2.6 8.0 8.4 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Lactamase_B_2 PF12706.2 CEP11692.1 - 9.1e-29 100.3 0.2 1.4e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEP11692.1 - 4.1e-16 59.1 0.0 5.9e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEP11692.1 - 0.00067 19.3 0.8 0.49 10.0 0.6 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily LRR_9 PF14580.1 CEP11692.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LysM PF01476.15 CEP11693.1 - 3.2e-09 36.5 0.3 0.0048 16.7 0.0 3.3 3 0 0 3 3 3 2 LysM domain KIAA1328 PF15369.1 CEP11693.1 - 0.75 9.5 8.3 1.1 9.0 5.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Pkinase PF00069.20 CEP11695.1 - 2.9e-53 180.6 0.1 5.1e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11695.1 - 4e-20 71.9 0.0 6.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.1 CEP11695.1 - 6e-12 45.8 0.0 0.0061 16.9 0.0 3.9 3 1 0 3 3 3 3 PAS domain PAS PF00989.19 CEP11695.1 - 8.2e-11 41.6 0.0 0.0098 15.6 0.0 4.5 4 0 0 4 4 4 3 PAS fold Kinase-like PF14531.1 CEP11695.1 - 2.2e-06 26.8 0.0 4.7e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP11695.1 - 0.00044 19.3 0.1 0.00078 18.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.5 CEP11695.1 - 0.00089 19.2 0.0 2.2 8.3 0.0 3.3 3 0 0 3 3 3 1 PAS fold APH PF01636.18 CEP11695.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Arrestin_C PF02752.17 CEP11696.1 - 2.6e-16 59.9 0.6 2.8e-14 53.3 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP11696.1 - 1.2e-07 31.7 0.1 1.2e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CEP11696.1 - 0.0023 17.4 0.0 0.0058 16.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like SAP30_Sin3_bdg PF13867.1 CEP11697.1 - 5.3e-17 61.4 0.4 9.4e-17 60.6 0.2 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ish1 PF10281.4 CEP11697.1 - 0.14 12.3 0.2 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Mucin PF01456.12 CEP11697.1 - 1.3 8.7 4.8 14 5.4 0.3 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C2H2_4 PF13894.1 CEP11698.1 - 0.00078 19.6 7.3 0.11 12.9 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP11698.1 - 0.0018 18.4 8.9 0.021 15.1 0.1 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP11698.1 - 0.0064 16.7 6.5 4.2 7.8 0.1 3.6 4 1 0 4 4 3 2 Zinc-finger double domain Zn-ribbon_8 PF09723.5 CEP11698.1 - 0.18 11.7 5.2 1.7 8.6 0.0 3.1 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.2 CEP11698.1 - 0.19 11.5 5.5 0.74 9.6 1.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.3 CEP11698.1 - 0.21 11.7 0.1 0.21 11.7 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding C1_3 PF07649.7 CEP11698.1 - 0.41 10.7 5.7 4.5 7.4 0.0 2.9 3 0 0 3 3 3 0 C1-like domain Zn_Tnp_IS1595 PF12760.2 CEP11698.1 - 0.42 10.4 4.2 7.4 6.4 0.0 2.8 3 0 0 3 3 3 0 Transposase zinc-ribbon domain C1_1 PF00130.17 CEP11698.1 - 1.3 8.7 3.9 8.1 6.2 0.8 2.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2321 PF10083.4 CEP11698.1 - 1.4 8.3 4.8 1 8.8 0.4 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Cript PF10235.4 CEP11698.1 - 1.5 9.2 5.8 7.6 6.9 1.6 2.8 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT ZZ PF00569.12 CEP11698.1 - 2.7 7.6 6.1 7.3 6.2 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, ZZ type zf-met PF12874.2 CEP11698.1 - 4.1 7.7 6.8 8.1 6.8 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-HYPF PF07503.7 CEP11698.1 - 5.6 6.4 7.4 5 6.6 0.1 2.9 3 0 0 3 3 3 0 HypF finger CwfJ_C_1 PF04677.10 CEP11700.1 - 2.1e-30 104.8 0.0 5.8e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CEP11700.1 - 6.3e-23 81.1 0.0 2e-22 79.4 0.0 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 CEP11700.1 - 3.5e-14 52.0 25.9 8.8e-06 25.1 2.0 3.9 2 1 2 4 4 4 3 Zinc knuckle zf-CCHC PF00098.18 CEP11700.1 - 1.6e-09 37.1 27.4 0.0014 18.4 0.8 4.2 4 0 0 4 4 4 3 Zinc knuckle HIT PF01230.18 CEP11700.1 - 0.0027 18.2 0.0 0.0067 16.9 0.0 1.7 1 0 0 1 1 1 1 HIT domain zf-CCHC_3 PF13917.1 CEP11700.1 - 1.7 8.4 11.5 4.9 6.9 0.1 3.3 2 1 1 3 3 3 0 Zinc knuckle zf-C4_ClpX PF06689.8 CEP11700.1 - 1.7 8.2 6.2 35 4.0 0.0 4.1 4 0 0 4 4 4 0 ClpX C4-type zinc finger zf-CCHC_4 PF14392.1 CEP11700.1 - 6 6.6 15.7 2.5 7.8 0.3 3.5 3 0 0 3 3 3 0 Zinc knuckle E1_DerP2_DerF2 PF02221.10 CEP11702.1 - 1.3e-22 80.5 0.5 1.6e-22 80.1 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CEP11702.1 - 2.6e-05 24.2 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 ML-like domain DUF2271 PF10029.4 CEP11702.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Peptidase_M24 PF00557.19 CEP11703.1 - 3.8e-44 150.7 0.0 4.4e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 CytochromB561_N PF09786.4 CEP11704.1 - 3.1e-06 25.9 0.8 4.9e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Cytochrome B561, N terminal Ribosomal_L10 PF00466.15 CEP11705.1 - 6.7e-26 90.1 0.4 1.2e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CEP11705.1 - 1.7e-19 69.9 4.6 7.8e-19 67.8 2.5 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L18e PF00828.14 CEP11707.1 - 9.6e-32 110.0 1.4 1.4e-31 109.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Histone PF00125.19 CEP11708.1 - 4.2e-24 84.4 0.3 6.2e-24 83.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEP11708.1 - 7.8e-07 29.0 1.2 1.6e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CEP11708.1 - 0.00016 21.8 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CEP11709.1 - 1.2e-25 89.4 0.0 1.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEP11709.1 - 2.4e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEP11710.1 - 1.9e-15 56.7 0.2 2.3e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEP11710.1 - 2.5e-05 24.3 0.1 3.5e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CEP11710.1 - 5.1e-05 23.1 0.2 7.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CEP11710.1 - 0.00019 21.3 0.1 0.00035 20.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CEP11710.1 - 0.0091 15.2 0.0 0.0091 15.2 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CEP11710.1 - 0.049 13.3 0.1 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 CEP11710.1 - 0.13 12.6 0.1 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CEP11711.1 - 1.4e-31 108.4 0.4 2.1e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEP11711.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CEP11711.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CEP11711.1 - 0.014 14.6 1.1 0.023 13.9 0.8 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CEP11711.1 - 0.019 14.6 0.1 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CEP11712.1 - 3.6e-24 84.6 0.4 5.8e-24 84.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEP11712.1 - 5.3e-07 29.6 0.8 1.5e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CEP11712.1 - 0.00014 22.0 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RRM_6 PF14259.1 CEP11713.1 - 5.5e-14 51.9 0.1 7.2e-07 29.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP11713.1 - 2.2e-08 33.6 0.1 0.0029 17.1 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 CEP11713.1 - 0.00047 19.1 5.8 0.00094 18.2 4.0 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_5 PF13893.1 CEP11713.1 - 0.0036 17.1 0.5 1.6 8.6 0.1 3.4 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 CEP11713.1 - 0.14 11.8 5.6 0.29 10.8 2.9 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zinc_ribbon_2 PF13240.1 CEP11713.1 - 0.84 9.2 3.3 1.8 8.1 2.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CEP11713.1 - 2.6 7.3 6.7 0.41 9.9 1.8 1.8 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 CEP11713.1 - 4.8 6.7 6.9 4.5 6.8 2.5 2.5 1 1 1 2 2 2 0 A2L zinc ribbon domain TMEM164 PF14808.1 CEP11714.1 - 1.1e-20 73.9 7.8 1.5e-20 73.4 5.4 1.1 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.5 CEP11714.1 - 9.2e-08 31.5 19.2 1.3e-07 31.1 13.3 1.2 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF788 PF05620.6 CEP11714.1 - 3.9 7.3 6.7 21 4.9 0.5 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF788) OrfB_Zn_ribbon PF07282.6 CEP11715.1 - 2.8 7.6 6.7 0.56 9.9 0.9 2.6 2 2 0 2 2 2 0 Putative transposase DNA-binding domain DRMBL PF07522.9 CEP11716.1 - 1.6e-31 108.6 0.0 3.1e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CEP11716.1 - 2e-07 30.7 0.0 5.6e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEP11716.1 - 0.0099 15.5 3.3 0.022 14.4 2.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily AAA_8 PF12780.2 CEP11716.1 - 0.038 12.9 0.0 2.5 7.0 0.0 2.2 1 1 0 2 2 2 0 P-loop containing dynein motor region D4 Rad50_zn_hook PF04423.9 CEP11716.1 - 0.054 12.9 0.7 0.11 11.9 0.5 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Dynamin_M PF01031.15 CEP11717.1 - 2.1e-105 351.7 0.8 2.1e-105 351.7 0.6 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CEP11717.1 - 4.9e-56 189.1 0.4 3.9e-55 186.2 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Ribosomal_S21e PF01249.13 CEP11717.1 - 3.8e-37 126.1 0.1 8.6e-37 124.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S21e GED PF02212.13 CEP11717.1 - 4.1e-26 90.7 4.6 4.1e-26 90.7 3.2 2.4 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CEP11717.1 - 0.0059 16.5 1.4 0.029 14.3 0.2 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CEP11717.1 - 0.035 14.5 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Ribosomal_S27e PF01667.12 CEP11719.1 - 8.4e-29 98.8 3.5 1.3e-28 98.2 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 Acyltransferase PF01553.16 CEP11719.1 - 1e-15 57.3 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase IBR PF01485.16 CEP11719.1 - 0.0044 16.8 0.5 0.0089 15.8 0.3 1.4 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CEP11719.1 - 0.29 10.4 7.3 0.026 13.8 1.8 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding GATA PF00320.22 CEP11722.1 - 4.3e-17 61.1 24.5 1.1e-15 56.6 3.4 2.7 3 0 0 3 3 3 2 GATA zinc finger ArfGap PF01412.13 CEP11722.1 - 0.0096 15.7 9.6 0.12 12.1 0.3 2.7 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf Cytochrom_c3_2 PF14537.1 CEP11722.1 - 0.047 14.0 12.1 0.11 12.8 2.0 2.7 2 0 0 2 2 2 0 Cytochrome c3 Elf1 PF05129.8 CEP11722.1 - 0.074 12.7 4.6 0.22 11.2 0.5 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 CEP11722.1 - 6.5 6.6 10.4 12 5.8 0.6 2.8 2 1 0 2 2 2 0 Double zinc ribbon p450 PF00067.17 CEP11723.1 - 3.9e-53 180.6 0.0 4.9e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.1 CEP11724.1 - 2.3e-12 46.8 0.0 4.3e-12 45.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP11724.1 - 5.9e-07 29.6 0.0 9.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP11724.1 - 0.0013 19.4 0.0 0.0026 18.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain CHCH PF06747.8 CEP11725.1 - 2.4e-06 27.3 6.4 4.1e-06 26.5 4.4 1.4 1 0 0 1 1 1 1 CHCH domain Gly-zipper_OmpA PF13436.1 CEP11725.1 - 0.0016 18.0 7.5 0.0016 18.0 5.2 2.4 2 2 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain DUF2076 PF09849.4 CEP11725.1 - 0.0038 17.3 26.2 0.013 15.5 18.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1903 PF08991.5 CEP11725.1 - 0.012 15.7 3.2 0.021 14.9 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Colipase-like PF15083.1 CEP11725.1 - 0.055 13.4 0.7 0.077 12.9 0.5 1.2 1 0 0 1 1 1 0 Colipase-like DUF605 PF04652.11 CEP11725.1 - 0.23 10.8 15.4 0.28 10.5 10.7 1.1 1 0 0 1 1 1 0 Vta1 like WES_acyltransf PF03007.11 CEP11725.1 - 4.7 6.6 5.7 1 8.8 0.1 2.0 1 1 1 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain V-ATPase_C PF03223.10 CEP11726.1 - 8.3e-122 406.6 9.8 9.3e-122 406.5 6.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 CEP11726.1 - 0.022 15.0 0.2 0.073 13.3 0.1 2.0 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Pkinase PF00069.20 CEP11727.1 - 1.4e-67 227.6 0.0 2.7e-67 226.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11727.1 - 1.2e-51 175.2 0.0 3e-51 173.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP11727.1 - 8.8e-05 21.6 0.0 0.00033 19.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C1_1 PF00130.17 CEP11727.1 - 0.0018 17.9 14.7 0.0051 16.5 10.2 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CEP11727.1 - 0.09 12.5 8.0 0.25 11.0 5.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 GPI-anchored PF10342.4 CEP11728.1 - 0.0016 18.8 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AA_permease PF00324.16 CEP11729.1 - 9.4e-124 413.3 43.3 1.1e-123 413.0 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEP11729.1 - 4.1e-45 154.0 46.7 5e-45 153.7 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.3 CEP11729.1 - 0.11 12.3 2.5 0.26 11.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Pterin_bind PF00809.17 CEP11730.1 - 3.1e-66 222.7 0.0 5.4e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.13 CEP11730.1 - 2.5e-42 143.6 1.1 5.1e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.15 CEP11730.1 - 6e-39 132.6 0.0 1.2e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) UQ_con PF00179.21 CEP11730.1 - 1.6e-12 47.0 0.1 8.3e-12 44.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CEP11730.1 - 0.012 15.5 0.0 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 RWD domain Pmp3 PF01679.12 CEP11731.1 - 2.5e-19 68.7 5.8 3e-19 68.4 4.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PrgI PF12666.2 CEP11731.1 - 0.015 15.4 0.2 0.019 15.0 0.1 1.1 1 0 0 1 1 1 0 PrgI family protein Whi5 PF08528.6 CEP11732.1 - 4.3e-07 29.3 0.1 4.3e-07 29.3 0.1 2.2 3 0 0 3 3 3 1 Whi5 like DUF4409 PF14365.1 CEP11732.1 - 0.032 14.3 2.1 0.089 12.9 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4409) MIT PF04212.13 CEP11734.1 - 2e-07 30.7 0.2 4.5e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain KilA-N PF04383.8 CEP11735.1 - 0.0024 17.5 1.4 0.0071 15.9 0.0 2.5 2 2 0 2 2 2 1 KilA-N domain Ribosomal_L29 PF00831.18 CEP11736.1 - 1.9e-13 49.8 2.2 1.9e-13 49.8 1.5 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 CEP11736.1 - 0.039 14.2 3.4 0.048 13.9 2.4 1.3 1 1 0 1 1 1 0 Ribosomal protein S9/S16 CENP-B_N PF04218.8 CEP11736.1 - 0.6 9.5 3.9 6.2 6.3 0.1 3.0 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain LTXXQ PF07813.7 CEP11736.1 - 1.1 9.7 8.6 7.5 7.0 6.0 2.3 1 1 0 1 1 1 0 LTXXQ motif family protein Tox-PL-2 PF15643.1 CEP11737.1 - 0.052 13.5 0.4 0.086 12.8 0.3 1.4 1 1 0 1 1 1 0 Papain fold toxin 2 DUF2691 PF10903.3 CEP11737.1 - 0.14 11.9 2.3 0.17 11.7 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) Meth_synt_2 PF01717.13 CEP11738.1 - 1.6e-146 487.4 0.0 5.8e-135 449.4 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CEP11738.1 - 1.1e-117 392.8 0.0 2.1e-104 349.1 0.1 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain RVT_1 PF00078.22 CEP11739.1 - 1.9e-08 33.9 0.0 3.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 CEP11742.1 - 4.5e-07 29.8 9.7 0.0047 17.1 1.1 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP11742.1 - 5.8e-07 29.3 6.7 0.0046 17.1 0.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP11742.1 - 0.00053 20.1 0.9 0.00053 20.1 0.7 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 CEP11742.1 - 0.028 14.5 5.9 1.6 9.0 0.2 3.5 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CEP11742.1 - 3.4 7.7 7.8 0.24 11.3 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Mito_carr PF00153.22 CEP11743.1 - 2.1e-43 145.9 6.0 1.9e-16 59.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mur_ligase_M PF08245.7 CEP11744.1 - 2.2e-06 27.8 1.7 4e-05 23.7 0.3 3.2 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CEP11744.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain MRP-L46 PF11788.3 CEP11744.1 - 0.032 14.8 0.3 1.9 9.1 0.2 2.4 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 MoCF_biosynth PF00994.19 CEP11745.1 - 4.5e-34 116.9 0.0 6.5e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain FAD_syn PF06574.7 CEP11745.1 - 0.12 11.9 0.0 0.96 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD synthetase Arrestin_N PF00339.24 CEP11746.1 - 1.1e-06 28.5 0.3 9.2e-05 22.2 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP11746.1 - 0.0002 21.4 0.2 0.00098 19.2 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain RolB_RolC PF02027.12 CEP11749.1 - 0.052 12.6 0.0 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 RolB/RolC glucosidase family T4_baseplate PF12322.3 CEP11750.1 - 0.063 12.5 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein Mid2 PF04478.7 CEP11751.1 - 3.2e-05 23.3 0.1 3.2e-05 23.3 0.0 3.7 2 1 2 4 4 4 1 Mid2 like cell wall stress sensor DUF1191 PF06697.7 CEP11751.1 - 0.013 14.3 0.6 0.034 12.9 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) Nop14 PF04147.7 CEP11751.1 - 0.014 13.3 18.6 0.018 12.9 12.9 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CEP11751.1 - 0.026 13.0 15.3 0.034 12.6 10.6 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 CEP11751.1 - 0.79 8.3 26.8 1.4 7.5 18.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pet191_N PF10203.4 CEP11752.1 - 0.0038 17.2 13.1 0.21 11.6 5.4 2.5 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CEP11752.1 - 0.0071 16.1 16.9 0.0094 15.7 2.8 2.5 2 1 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 CEP11752.1 - 0.046 13.6 13.9 0.43 10.5 3.0 2.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.8 CEP11752.1 - 0.092 12.7 11.2 1.2 9.2 2.0 3.3 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) DUF3768 PF12599.3 CEP11752.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3768) Herpes_UL7 PF01677.11 CEP11752.1 - 0.099 11.9 1.1 0.32 10.2 0.7 1.8 1 1 0 1 1 1 0 Herpesvirus UL7 like CHCH PF06747.8 CEP11752.1 - 1.5 8.8 15.3 0.43 10.5 0.5 3.0 2 1 1 3 3 3 0 CHCH domain NDUF_B7 PF05676.8 CEP11752.1 - 3 7.3 11.4 0.25 10.7 2.7 2.4 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF1903 PF08991.5 CEP11752.1 - 6.6 6.9 12.9 0.2 11.8 1.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1903) UPF0203 PF05254.7 CEP11752.1 - 9.2 6.2 13.0 8.4 6.3 0.3 3.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Fis1_TPR_C PF14853.1 CEP11753.1 - 2.2e-23 81.8 0.1 4.1e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CEP11753.1 - 5.9e-14 51.0 0.0 1.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat DUF357 PF04010.8 CEP11753.1 - 0.025 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TPR_19 PF14559.1 CEP11753.1 - 0.032 14.5 0.2 0.069 13.4 0.2 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP11753.1 - 0.066 13.1 0.2 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEP11753.1 - 0.079 13.6 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Trans_reg_C PF00486.23 CEP11753.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Pox_A_type_inc PF04508.7 CEP11754.1 - 0.023 14.4 1.8 0.065 13.0 0.2 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.5 CEP11754.1 - 3.5 7.7 11.5 0.17 12.0 3.2 2.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUSP PF06337.7 CEP11755.1 - 0.014 15.7 0.8 0.12 12.8 0.0 2.4 2 0 0 2 2 2 0 DUSP domain Phi-29_GP4 PF05464.6 CEP11755.1 - 0.044 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Pollen_allerg_1 PF01357.16 CEP11755.1 - 0.1 12.4 0.2 0.35 10.7 0.1 1.8 2 0 0 2 2 2 0 Pollen allergen Mis12 PF05859.7 CEP11757.1 - 8.7e-09 35.3 2.1 8.7e-09 35.3 1.4 2.0 1 1 1 2 2 2 1 Mis12 protein DUF4055 PF13264.1 CEP11757.1 - 0.0011 19.0 0.2 0.088 12.8 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4055) FKBP_N PF01346.13 CEP11757.1 - 0.15 12.1 3.8 0.21 11.6 0.9 2.2 1 1 2 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF16 PF01519.11 CEP11757.1 - 1 9.6 9.1 1.3 9.2 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Wbp11 PF09429.5 CEP11757.1 - 4.6 7.3 6.5 1.5 8.8 0.8 2.7 2 1 0 2 2 2 0 WW domain binding protein 11 DivIC PF04977.10 CEP11757.1 - 6 6.4 8.8 0.59 9.6 2.2 2.2 2 1 0 3 3 3 0 Septum formation initiator Pkinase PF00069.20 CEP11758.1 - 2.6e-23 82.5 0.0 4.8e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CEP11758.1 - 8.5e-22 76.1 3.8 4.4e-09 35.8 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat HEAT PF02985.17 CEP11758.1 - 5.1e-11 41.6 6.6 0.003 17.5 0.0 5.6 5 0 0 5 5 5 4 HEAT repeat Pkinase_Tyr PF07714.12 CEP11758.1 - 1.3e-07 30.9 0.0 2.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 CEP11758.1 - 9.1e-06 25.8 0.4 0.0046 17.1 0.3 3.6 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 CEP11758.1 - 0.00011 22.5 1.5 0.0017 18.7 0.4 3.3 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 CEP11758.1 - 0.0076 16.1 0.4 2.7 7.8 0.1 3.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 CEP11758.1 - 0.04 13.8 0.5 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) APH PF01636.18 CEP11758.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CorA PF01544.13 CEP11759.1 - 2.5e-42 144.9 4.6 1.4e-21 76.7 0.1 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF3752 PF12572.3 CEP11759.1 - 0.045 13.8 2.5 0.1 12.7 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) NTP_transferase PF00483.18 CEP11759.1 - 0.11 11.8 2.0 0.18 11.0 0.9 1.6 2 0 0 2 2 2 0 Nucleotidyl transferase U3_assoc_6 PF08640.6 CEP11760.1 - 1.4e-26 92.0 4.7 7.6e-26 89.6 3.3 2.4 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 CEP11760.1 - 8.8e-07 29.0 12.2 0.47 11.2 0.0 7.0 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP11760.1 - 4.4e-06 27.2 5.7 0.81 10.4 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat NRDE-2 PF08424.5 CEP11760.1 - 3.4e-05 22.9 22.9 0.00023 20.1 1.8 4.4 2 2 2 4 4 4 3 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 CEP11760.1 - 0.00017 21.1 12.8 0.17 11.5 0.3 4.9 3 2 2 5 5 5 3 TPR repeat TPR_17 PF13431.1 CEP11760.1 - 0.00026 20.9 8.2 14 6.2 0.0 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP11760.1 - 0.0013 18.4 8.4 1.7 8.7 0.2 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.9 CEP11760.1 - 0.0028 17.4 0.4 0.0028 17.4 0.3 3.8 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CEP11760.1 - 0.24 11.7 13.7 0.86 9.9 0.3 5.9 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP11760.1 - 0.42 11.1 12.3 23 5.7 0.2 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat IIGP PF05049.8 CEP11761.1 - 4.1e-25 88.3 0.0 5.8e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 CEP11761.1 - 2.4e-06 27.4 0.0 4.4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CEP11761.1 - 0.00012 22.4 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 CEP11761.1 - 0.00077 19.3 0.1 0.0029 17.4 0.0 1.9 2 1 1 3 3 3 1 Dynamin family Miro PF08477.8 CEP11761.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CEP11761.1 - 0.0022 17.1 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEP11761.1 - 0.0053 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP11761.1 - 0.0057 16.6 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Septin PF00735.13 CEP11761.1 - 0.0097 14.9 0.0 0.027 13.4 0.0 1.7 2 0 0 2 2 2 1 Septin AAA_17 PF13207.1 CEP11761.1 - 0.013 16.3 0.1 0.024 15.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CEP11761.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CEP11761.1 - 0.017 14.6 0.0 0.048 13.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 CEP11761.1 - 0.02 14.0 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CEP11761.1 - 0.023 14.4 0.1 0.054 13.2 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CEP11761.1 - 0.024 14.7 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CEP11761.1 - 0.026 13.4 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 CEP11761.1 - 0.042 13.8 0.1 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CEP11761.1 - 0.058 12.8 0.2 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 CEP11761.1 - 0.06 13.1 1.0 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 FeoB_N PF02421.13 CEP11761.1 - 0.066 12.4 0.1 0.13 11.4 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 CEP11761.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CEP11761.1 - 0.091 12.6 0.6 0.22 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 CEP11761.1 - 0.099 12.3 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CEP11761.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF498 PF04430.9 CEP11762.1 - 3e-25 87.8 0.0 5.7e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Acyltransferase PF01553.16 CEP11763.1 - 2.8e-11 42.9 0.0 5.8e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase EMP24_GP25L PF01105.19 CEP11763.1 - 0.0011 18.6 0.1 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Statherin PF03875.8 CEP11765.1 - 3.6 7.5 6.5 5.7 6.9 4.5 1.4 1 0 0 1 1 1 0 Statherin Rad17 PF03215.10 CEP11766.1 - 0.02 13.6 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PyrI PF01948.13 CEP11770.1 - 0.017 15.1 0.2 0.062 13.3 0.0 2.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain LPP20 PF02169.11 CEP11770.1 - 0.25 11.4 2.7 0.4 10.8 1.4 1.6 1 1 0 1 1 1 0 LPP20 lipoprotein CTP_synth_N PF06418.9 CEP11771.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 CTP synthase N-terminus RVT_1 PF00078.22 CEP11772.1 - 2e-18 66.5 0.1 4.2e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pico_P1A PF02226.11 CEP11772.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) Pol_alpha_B_N PF08418.5 CEP11772.1 - 0.18 11.3 1.7 1.5 8.2 0.5 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal RVP_2 PF08284.6 CEP11773.1 - 3.2e-06 27.1 0.1 6.8e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEP11773.1 - 4e-06 27.2 0.0 8.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP11773.1 - 4.2e-05 23.2 0.0 8.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CEP11773.1 - 0.00095 18.5 0.2 0.0018 17.6 0.0 1.5 2 0 0 2 2 2 1 Ty3 transposon peptidase CRPV_capsid PF08762.5 CEP11773.1 - 0.025 14.0 0.0 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 CRPV capsid protein like RVP PF00077.15 CEP11773.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 CEP11774.1 - 1e-18 67.5 0.0 2.1e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_A_exo1 PF01612.15 CEP11775.1 - 8.7e-08 31.8 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Dam PF05869.6 CEP11776.1 - 1.2e-06 28.0 8.2 1.6e-06 27.6 1.9 2.1 1 1 1 2 2 2 2 DNA N-6-adenine-methyltransferase (Dam) RNase_H PF00075.19 CEP11776.1 - 7.8e-06 26.2 0.1 1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 RNase H ELL PF10390.4 CEP11776.1 - 0.14 11.3 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Kinesin PF00225.18 CEP11779.1 - 2.5e-85 286.1 0.7 5.9e-85 284.9 0.4 3.2 3 1 1 4 4 4 2 Kinesin motor domain DUF3694 PF12473.3 CEP11779.1 - 2.5e-36 124.3 0.4 1.2e-35 122.2 0.3 2.3 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 CEP11779.1 - 5.2e-07 29.8 1.5 0.00092 19.3 0.1 3.1 1 1 1 2 2 2 2 PH domain FHA PF00498.21 CEP11779.1 - 1e-05 25.5 0.0 7.9e-05 22.6 0.0 2.6 3 0 0 3 3 3 1 FHA domain KIF1B PF12423.3 CEP11779.1 - 0.0027 17.7 0.0 0.0068 16.4 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein 1B PH_11 PF15413.1 CEP11779.1 - 0.016 15.4 3.7 1.6 9.0 0.2 3.7 2 1 1 3 3 3 0 Pleckstrin homology domain SHR3_chaperone PF08229.6 CEP11779.1 - 0.065 12.1 1.1 0.15 11.0 0.7 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 Acyltransferase PF01553.16 CEP11780.1 - 3.8e-11 42.5 0.0 1e-09 37.9 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase ICAT PF06384.6 CEP11780.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT FAD_binding_2 PF00890.19 CEP11781.1 - 6.9e-84 282.1 0.1 1e-83 281.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 CEP11781.1 - 4.7e-25 87.1 0.0 2e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 CEP11781.1 - 1.2e-10 40.8 0.1 6.8e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP11781.1 - 6.2e-09 35.7 0.3 3.5e-08 33.3 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CEP11781.1 - 6.2e-08 32.1 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEP11781.1 - 4.1e-06 26.8 2.6 0.00076 19.4 1.8 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEP11781.1 - 3.1e-05 22.6 2.9 0.00034 19.2 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CEP11781.1 - 0.00029 19.9 1.1 0.007 15.4 0.0 2.8 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 CEP11781.1 - 0.0027 16.6 0.9 0.0073 15.2 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CEP11781.1 - 0.0028 17.7 0.2 0.01 15.9 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEP11781.1 - 0.0067 15.5 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CEP11781.1 - 0.025 13.5 0.1 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.13 CEP11781.1 - 0.073 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Tecti-min-caps PF09300.5 CEP11781.1 - 0.075 12.8 0.3 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 Tectiviridae, minor capsid Pyr_redox PF00070.22 CEP11781.1 - 0.096 13.0 0.2 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CEP11781.1 - 0.11 11.5 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Galactosyl_T PF01762.16 CEP11782.1 - 2.9e-26 92.2 0.0 4.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.3 CEP11782.1 - 1.1e-08 34.9 11.7 2.3e-08 33.7 8.1 1.5 1 0 0 1 1 1 1 N-glycosylation protein DUF3169 PF11368.3 CEP11782.1 - 1.2 8.2 5.6 8.2 5.5 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3169) TM2 PF05154.11 CEP11783.1 - 2.5e-15 56.4 3.3 2.5e-15 56.4 2.3 1.7 2 0 0 2 2 2 1 TM2 domain OppC_N PF12911.2 CEP11783.1 - 0.046 13.0 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C FA_hydroxylase PF04116.8 CEP11784.1 - 1.5e-16 60.7 13.3 1.5e-16 60.7 9.2 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HECT PF00632.20 CEP11785.1 - 3.4e-75 253.1 0.0 6.8e-75 252.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CLTH PF10607.4 CEP11786.1 - 1.1e-24 86.8 0.4 1.7e-24 86.1 0.3 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 CEP11786.1 - 1.6e-21 76.6 0.0 2.8e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Spore_IV_A PF09547.5 CEP11786.1 - 0.0057 15.3 0.2 0.0085 14.8 0.2 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) LisH PF08513.6 CEP11786.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 LisH Ribosomal_S10 PF00338.17 CEP11787.1 - 8.4e-29 99.2 0.0 1.4e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e OPT PF03169.10 CEP11788.1 - 3.5e-143 478.2 23.0 4e-143 478.0 15.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribosomal_S9 PF00380.14 CEP11789.1 - 5.5e-37 126.6 0.1 6.3e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 14-3-3 PF00244.15 CEP11790.1 - 1.3e-114 381.2 6.5 1.5e-114 380.9 4.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 CEP11790.1 - 0.059 13.3 1.7 1.2 9.0 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Gti1_Pac2 PF09729.4 CEP11791.1 - 7.6e-52 175.5 0.5 7.6e-52 175.5 0.3 2.3 2 0 0 2 2 2 2 Gti1/Pac2 family AMP-binding PF00501.23 CEP11792.1 - 1.5e-82 277.1 0.0 1.9e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP11792.1 - 1.1e-10 42.2 0.0 2.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Vps26 PF03643.10 CEP11793.1 - 1.9e-126 420.4 6.9 2.3e-126 420.2 4.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CEP11793.1 - 0.0029 17.4 1.0 0.068 12.9 0.1 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain AAA_18 PF13238.1 CEP11794.1 - 8.8e-25 87.4 1.1 2.7e-24 85.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP11794.1 - 4.9e-14 53.1 0.2 8.9e-14 52.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 CEP11794.1 - 1.1e-05 25.2 0.0 0.00034 20.5 0.0 2.2 1 1 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 CEP11794.1 - 2.2e-05 24.3 0.0 7.7e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CEP11794.1 - 4.4e-05 23.6 1.0 7.2e-05 23.0 0.2 1.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CEP11794.1 - 0.00024 21.0 0.1 0.00049 20.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP11794.1 - 0.00063 19.8 0.0 0.001 19.2 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 CEP11794.1 - 0.00083 19.0 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 CEP11794.1 - 0.0019 17.9 1.0 0.0036 17.0 0.5 1.6 1 1 0 1 1 1 1 NTPase MobB PF03205.9 CEP11794.1 - 0.0025 17.5 0.3 0.0043 16.7 0.2 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 CEP11794.1 - 0.0041 16.1 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 CEP11794.1 - 0.0059 16.4 0.2 0.01 15.6 0.1 1.6 1 1 0 1 1 1 1 Shikimate kinase Cytidylate_kin2 PF13189.1 CEP11794.1 - 0.0068 16.3 0.2 0.011 15.7 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 CEP11794.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 CEP11794.1 - 0.016 14.0 0.2 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 CEP11794.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 CEP11794.1 - 0.027 13.9 0.3 0.041 13.3 0.1 1.6 2 1 0 2 2 2 0 AAA-like domain KTI12 PF08433.5 CEP11794.1 - 0.033 13.4 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 CEP11794.1 - 0.064 12.7 0.1 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_11 PF13086.1 CEP11794.1 - 0.068 12.7 0.0 0.086 12.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain Phage_pRha PF09669.5 CEP11794.1 - 0.077 13.3 0.1 0.21 11.9 0.1 1.8 1 1 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) AAA_5 PF07728.9 CEP11794.1 - 0.086 12.5 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 CEP11794.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 CEP11794.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 CEP11794.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CEP11794.1 - 0.13 11.3 1.6 0.22 10.5 0.6 1.6 1 1 0 1 1 1 0 KaiC AAA_30 PF13604.1 CEP11794.1 - 0.15 11.6 0.2 0.27 10.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain TPP_enzyme_N PF02776.13 CEP11795.1 - 1.8e-58 196.8 0.1 8.5e-58 194.6 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CEP11795.1 - 2.6e-52 176.4 0.6 1.5e-50 170.7 0.2 3.0 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CEP11795.1 - 5.4e-38 129.8 0.3 1.9e-37 128.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain IlvN PF07991.7 CEP11796.1 - 1e-45 155.0 0.0 1.9e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 CEP11796.1 - 2.8e-45 153.8 0.0 7.5e-45 152.4 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CEP11796.1 - 0.0072 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CEP11796.1 - 0.0085 16.5 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 CEP11796.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 CEP11796.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Iso_dh PF00180.15 CEP11797.1 - 3e-128 427.6 0.0 3.5e-128 427.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Auxin_repressed PF05564.7 CEP11797.1 - 0.057 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Dormancy/auxin associated protein CsbD PF05532.7 CEP11798.1 - 0.00092 18.8 0.2 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 CsbD-like ABC_membrane PF00664.18 CEP11799.1 - 2.8e-84 282.7 39.1 9.5e-47 159.6 9.3 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP11799.1 - 4.5e-52 175.9 0.0 2.4e-28 99.1 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 CEP11799.1 - 5.8e-11 42.0 0.0 8.3e-05 21.9 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 CEP11799.1 - 5.1e-06 26.4 0.4 0.027 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CEP11799.1 - 2.9e-05 23.3 0.3 0.0041 16.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEP11799.1 - 3.1e-05 23.4 1.0 0.034 13.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CEP11799.1 - 3.2e-05 24.0 3.1 1.4 8.8 0.0 5.0 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 CEP11799.1 - 4.2e-05 23.6 1.2 0.14 12.0 0.3 2.8 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 CEP11799.1 - 0.00039 20.9 1.6 0.14 12.6 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 CEP11799.1 - 0.0019 17.5 0.1 0.89 8.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 CEP11799.1 - 0.0074 16.1 3.6 0.014 15.2 0.2 2.5 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 CEP11799.1 - 0.0091 16.3 0.2 1.5 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP11799.1 - 0.014 16.1 0.0 3.4 8.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CEP11799.1 - 0.021 14.6 3.8 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 CEP11799.1 - 0.032 13.6 2.3 6.1 6.1 0.0 3.1 2 1 1 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 CEP11799.1 - 0.048 12.7 0.2 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 CEP11799.1 - 0.06 12.1 0.1 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_22 PF13401.1 CEP11799.1 - 0.12 12.4 2.3 12 6.0 0.0 3.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CEP11799.1 - 0.19 11.1 0.1 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 CEP11799.1 - 0.3 10.7 1.0 14 5.3 0.1 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CEP11799.1 - 2.6 7.5 4.4 17 4.8 0.1 3.5 4 0 0 4 4 4 0 AAA domain DUF1014 PF06244.7 CEP11800.1 - 2.8e-28 98.5 15.9 2.8e-28 98.5 11.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) Glyco_transf_49 PF13896.1 CEP11801.1 - 1.3e-34 119.7 2.2 4.3e-27 95.0 0.5 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DUF1071 PF06378.6 CEP11801.1 - 0.1 11.7 0.1 0.29 10.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1071) Sec1 PF00995.18 CEP11802.1 - 2.6e-147 491.8 3.9 3e-147 491.6 2.7 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.14 CEP11802.1 - 0.048 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain Syntaxin PF00804.20 CEP11802.1 - 0.093 12.9 0.4 1.2 9.3 0.3 2.6 1 1 0 1 1 1 0 Syntaxin Pkinase PF00069.20 CEP11803.1 - 6.9e-70 235.1 0.0 1.6e-69 233.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11803.1 - 3.6e-47 160.6 0.0 6.9e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CEP11803.1 - 5.9e-26 90.4 0.1 1.3e-25 89.3 0.1 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 RA PF00788.18 CEP11803.1 - 2.3e-11 44.0 0.0 5.4e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 CEP11803.1 - 2.2e-10 40.5 0.0 5.7e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CEP11803.1 - 1.3e-09 37.7 0.0 3.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CEP11803.1 - 2.5e-08 33.2 0.0 4.1e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CEP11803.1 - 0.084 11.6 0.8 0.81 8.4 0.1 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Herpes_gE PF02480.11 CEP11804.1 - 0.0032 15.7 0.2 0.0049 15.1 0.1 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2681 PF10883.3 CEP11804.1 - 0.032 14.4 0.2 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DivIC PF04977.10 CEP11804.1 - 0.038 13.4 0.1 0.09 12.2 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator NPDC1 PF06809.6 CEP11804.1 - 0.12 11.1 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) WD40 PF00400.27 CEP11805.1 - 5.8e-38 127.4 11.1 7.6e-10 38.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEP11805.1 - 0.0065 15.2 0.9 0.46 9.1 0.2 2.8 2 1 0 2 2 2 2 Nup133 N terminal like DUF3027 PF11228.3 CEP11805.1 - 0.16 11.6 1.2 14 5.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) WD40 PF00400.27 CEP11806.1 - 1e-16 60.1 3.0 5e-07 29.3 0.2 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Ammonium_transp PF00909.16 CEP11807.1 - 1.4e-122 409.0 25.5 1.6e-122 408.8 17.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_3 PF05106.7 CEP11807.1 - 0.026 14.4 0.8 0.026 14.4 0.5 2.9 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) START PF01852.14 CEP11808.1 - 1.3e-12 47.5 0.0 1.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 START domain Cadherin-like PF12733.2 CEP11808.1 - 0.0089 16.2 1.2 0.021 15.1 0.9 1.7 1 0 0 1 1 1 1 Cadherin-like beta sandwich domain WH1 PF00568.18 CEP11809.1 - 6.8e-23 80.5 0.1 1e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 CEP11809.1 - 2.1e-08 34.4 0.4 1.2e-07 32.0 0.1 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Ribonucleas_3_3 PF14622.1 CEP11810.1 - 7.2e-25 87.4 0.0 1.2e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CEP11810.1 - 1.3e-12 48.1 0.0 3.6e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 CEP11810.1 - 2e-05 25.0 0.0 4.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif MIR PF02815.14 CEP11811.1 - 3e-16 59.5 0.1 1.2e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.6 CEP11811.1 - 0.00029 19.9 0.1 0.00076 18.5 0.0 1.7 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor FGGY_C PF02782.11 CEP11812.1 - 2.1e-44 151.5 0.0 3.2e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CEP11812.1 - 1.7e-26 93.0 0.5 1.6e-25 89.8 0.3 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 CEP11812.1 - 0.00045 19.6 0.0 0.042 13.1 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 CEP11812.1 - 0.011 15.1 0.0 0.032 13.5 0.0 1.8 2 0 0 2 2 2 0 Hexokinase MFS_1 PF07690.11 CEP11813.1 - 1.4e-30 106.2 66.6 2.4e-23 82.4 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP11813.1 - 1.3e-08 33.9 29.6 3e-07 29.4 12.1 3.1 1 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 CEP11813.1 - 5.4e-08 31.7 19.7 4.6e-05 22.0 0.6 2.6 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like HemY_N PF07219.8 CEP11813.1 - 0.092 12.3 2.2 0.17 11.4 0.3 2.3 2 0 0 2 2 2 0 HemY protein N-terminus F-box-like PF12937.2 CEP11814.1 - 1.8e-11 43.5 1.1 1e-10 41.1 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP11814.1 - 0.00014 21.4 0.1 0.0021 17.6 0.0 2.7 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 CEP11814.1 - 0.013 15.5 2.0 0.088 12.9 0.1 3.2 4 0 0 4 4 4 0 Leucine Rich repeat Prenyltrans PF00432.16 CEP11815.1 - 4.1e-61 202.1 1.7 1.7e-16 59.4 0.0 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CEP11815.1 - 4.1e-42 143.1 0.0 2.2e-15 57.0 0.0 3.7 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CEP11815.1 - 2.6e-11 43.5 0.0 5.4e-05 23.1 0.0 3.3 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 CEP11815.1 - 0.0022 17.2 0.0 0.12 11.5 0.0 2.7 3 1 0 3 3 3 1 A-macroglobulin complement component La PF05383.12 CEP11816.1 - 9.4e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_3 PF08777.6 CEP11816.1 - 0.0012 18.7 0.1 0.0012 18.7 0.0 3.2 2 2 1 3 3 3 1 RNA binding motif MADF_DNA_bdg PF10545.4 CEP11816.1 - 0.12 12.5 3.2 0.46 10.7 2.1 2.1 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF155 PF02582.9 CEP11817.1 - 1e-60 204.6 0.9 1e-60 204.6 0.6 1.9 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 SURF4 PF02077.10 CEP11818.1 - 2.5e-85 286.0 4.0 2.9e-85 285.8 2.8 1.0 1 0 0 1 1 1 1 SURF4 family Anoctamin PF04547.7 CEP11819.1 - 3.7e-111 371.9 17.4 4.5e-111 371.6 12.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel S1FA PF04689.8 CEP11819.1 - 0.32 10.9 5.7 0.098 12.5 0.3 2.6 2 0 0 2 2 2 0 DNA binding protein S1FA Tim17 PF02466.14 CEP11820.1 - 2.6e-08 33.9 6.9 5.4e-08 32.9 4.8 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 CEP11820.1 - 0.079 13.0 6.1 1.8 8.7 0.6 3.0 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 CEP11820.1 - 0.45 10.1 3.1 0.45 10.1 0.8 1.9 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain HEAT PF02985.17 CEP11822.1 - 2e-37 123.8 28.2 0.0035 17.2 0.0 13.5 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.1 CEP11822.1 - 1.8e-33 114.6 5.4 6.2e-07 29.6 0.1 6.2 4 1 2 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 CEP11822.1 - 2.1e-13 50.4 4.2 0.00016 21.9 0.0 6.6 4 3 4 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CEP11822.1 - 3.8e-10 39.9 12.4 0.00058 20.2 0.2 7.3 6 2 2 8 8 8 3 HEAT-like repeat WD40 PF00400.27 CEP11822.1 - 6.2e-10 38.5 0.8 3.5e-05 23.5 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Adaptin_N PF01602.15 CEP11822.1 - 2e-07 29.7 5.4 0.022 13.0 0.0 3.4 3 1 0 3 3 3 3 Adaptin N terminal region DUF2435 PF10363.4 CEP11822.1 - 8.5e-05 22.3 5.3 5.7 6.9 0.1 5.4 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 CEP11822.1 - 0.00062 19.6 3.3 0.034 13.9 0.0 4.1 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CEP11822.1 - 0.00089 18.9 4.5 15 5.5 0.0 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CEP11822.1 - 0.0011 18.4 1.1 2.3 7.5 0.0 4.2 3 1 1 4 4 4 1 CLASP N terminal DKNYY PF13644.1 CEP11822.1 - 0.0064 16.7 0.6 0.018 15.3 0.5 1.7 1 0 0 1 1 1 1 DKNYY family DUF2415 PF10313.4 CEP11822.1 - 0.034 13.8 0.0 0.34 10.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) NPR1_like_C PF12313.3 CEP11822.1 - 0.051 13.0 0.2 6.2 6.1 0.0 2.6 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal DNA_alkylation PF08713.6 CEP11822.1 - 0.074 12.5 0.4 1.8 8.0 0.0 2.9 3 0 0 3 3 3 0 DNA alkylation repair enzyme HAD_2 PF13419.1 CEP11823.1 - 6.2e-20 72.1 0.0 8.5e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP11823.1 - 3e-14 53.9 0.2 1.1e-12 48.8 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP11823.1 - 3.2e-09 36.3 0.1 7.4e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 CEP11823.1 - 0.00029 21.0 0.0 0.0009 19.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4187 PF13821.1 CEP11824.1 - 1.2e-19 69.5 9.0 1.1e-18 66.5 6.3 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CEP11824.1 - 6.7e-12 45.0 8.3 1.3e-11 44.0 5.7 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CEP11824.1 - 0.00013 21.6 5.4 0.00013 21.6 3.7 3.0 2 1 1 3 3 3 1 DExH-box splicing factor binding site Neur_chan_memb PF02932.11 CEP11824.1 - 9.5 6.0 7.2 18 5.1 5.0 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GATA PF00320.22 CEP11827.1 - 1e-26 91.9 18.5 1.3e-14 53.2 3.0 3.3 3 1 0 3 3 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CEP11827.1 - 0.00017 20.8 5.8 0.017 14.4 0.3 2.9 3 0 0 3 3 3 2 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 CEP11827.1 - 0.011 15.3 7.8 0.29 10.7 1.3 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 SSP160 PF06933.6 CEP11827.1 - 0.019 13.0 10.1 0.024 12.6 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HypA PF01155.14 CEP11827.1 - 0.039 13.6 4.2 0.44 10.2 1.0 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family LIM PF00412.17 CEP11827.1 - 0.24 11.4 6.4 2.3 8.3 0.4 2.8 2 0 0 2 2 2 0 LIM domain Auto_anti-p27 PF06677.7 CEP11827.1 - 1.5 8.6 5.2 1.6 8.5 0.3 2.8 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3439 PF11921.3 CEP11827.1 - 1.6 8.4 17.2 4.4 7.0 11.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CEP11827.1 - 2.4 5.7 13.1 0.067 10.9 4.2 1.8 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Ribosomal_L32p PF01783.18 CEP11827.1 - 3.2 7.9 12.4 30 4.8 2.8 4.2 2 2 0 2 2 2 0 Ribosomal L32p protein family Elf1 PF05129.8 CEP11827.1 - 3.3 7.4 12.6 0.3 10.7 1.1 3.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 CEP11827.1 - 4.3 7.0 9.3 1.1 8.9 0.7 3.2 4 0 0 4 4 3 0 Putative transposase DNA-binding domain Mucin PF01456.12 CEP11827.1 - 5.1 6.8 25.2 12 5.6 17.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Stc1 PF12898.2 CEP11827.1 - 5.7 7.0 11.4 1.6 8.8 3.3 2.8 2 0 0 2 2 2 0 Stc1 domain DZR PF12773.2 CEP11827.1 - 6.3 6.7 13.1 8.4 6.2 1.9 3.4 3 1 1 4 4 3 0 Double zinc ribbon zf-CHY PF05495.7 CEP11827.1 - 8.9 6.5 10.4 8.1 6.6 2.4 2.7 2 0 0 2 2 2 0 CHY zinc finger bZIP_Maf PF03131.12 CEP11829.1 - 0.0037 17.5 2.5 0.0037 17.5 1.7 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor Ribonuclease_3 PF00636.21 CEP11830.1 - 9.8e-44 148.4 0.0 2.4e-23 82.7 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CEP11830.1 - 3.8e-29 101.2 0.0 1.8e-17 63.4 0.0 3.1 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 CEP11830.1 - 3.7e-18 65.0 1.3 1e-16 60.4 0.0 3.5 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.26 CEP11830.1 - 1.5e-17 63.2 0.2 3.6e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP11830.1 - 1.1e-10 41.2 0.0 2.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CEP11830.1 - 5.9e-07 29.4 0.0 2e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PAZ PF02170.17 CEP11830.1 - 6e-07 28.8 0.2 1.3e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 PAZ domain dsrm PF00035.20 CEP11830.1 - 5.9e-05 23.5 2.1 0.00034 21.1 0.6 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif SNF2_N PF00176.18 CEP11830.1 - 0.0019 17.0 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain KRBA1 PF15287.1 CEP11830.1 - 0.2 11.0 0.2 0.45 9.9 0.2 1.5 1 0 0 1 1 1 0 KRBA1 family repeat GATase_5 PF13507.1 CEP11831.1 - 1.5e-100 335.3 0.0 2.2e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CEP11831.1 - 4.5e-46 156.6 0.4 1.4e-25 90.0 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CEP11831.1 - 1.3e-24 86.1 2.7 8.6e-24 83.6 0.0 3.4 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain TRP_2 PF08344.6 CEP11831.1 - 0.028 14.3 0.4 0.71 9.8 0.1 2.9 3 0 0 3 3 3 0 Transient receptor ion channel II Glyco_hydro_31 PF01055.21 CEP11833.1 - 7.3e-102 341.4 2.5 9.4e-102 341.0 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CEP11833.1 - 7.9e-19 67.2 2.7 1.4e-18 66.5 0.2 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DNA_pol_A_exo1 PF01612.15 CEP11834.1 - 1.1e-48 164.9 0.3 1.8e-48 164.3 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CEP11834.1 - 1.1e-16 60.9 0.0 2.4e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 CEP11834.1 - 2.9e-12 46.1 0.0 1.1e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 HRDC domain Glyco_hydro_47 PF01532.15 CEP11835.1 - 8.7e-144 479.5 0.0 1.1e-143 479.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 YcfA PF07927.7 CEP11835.1 - 0.047 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 YcfA-like protein SHQ1 PF04925.10 CEP11835.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 SHQ1 protein MULE PF10551.4 CEP11836.1 - 1.8e-07 31.2 2.4 1.4e-06 28.3 0.6 2.4 1 1 1 2 2 2 1 MULE transposase domain Tetraspannin PF00335.15 CEP11838.1 - 6.7e-14 51.7 11.7 1e-13 51.1 8.1 1.2 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.18 CEP11838.1 - 1.3 8.8 9.2 3.7 7.3 6.4 1.8 1 1 0 1 1 1 0 Membrane-associating domain Mog1 PF04603.7 CEP11839.1 - 8.4e-35 119.7 1.1 8.4e-35 119.7 0.8 1.3 2 0 0 2 2 2 1 Ran-interacting Mog1 protein DUF1864 PF08933.6 CEP11839.1 - 0.02 13.4 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) HisKA_2 PF07568.7 CEP11841.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase Septin PF00735.13 CEP11842.1 - 7.5e-55 185.9 4.2 5.8e-40 137.0 1.4 2.0 2 0 0 2 2 2 2 Septin Ins_P5_2-kin PF06090.7 CEP11842.1 - 0.009 15.0 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase MMR_HSR1 PF01926.18 CEP11842.1 - 0.014 15.3 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SLIDE PF09111.5 CEP11842.1 - 0.042 13.5 0.2 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 SLIDE YhdB PF14148.1 CEP11842.1 - 0.073 12.8 1.4 5.8 6.7 0.1 3.1 2 1 1 3 3 3 0 YhdB-like protein Cyclin PF08613.6 CEP11843.1 - 2.3e-40 138.4 0.1 5.1e-40 137.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin DUF2058 PF09831.4 CEP11843.1 - 0.014 15.2 3.3 0.014 15.2 2.3 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2058) Peptidase_M17 PF00883.16 CEP11844.1 - 5.7e-114 380.1 0.2 8e-114 379.6 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CEP11844.1 - 1.3e-14 54.0 1.3 2.5e-14 53.1 0.9 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Sterol-sensing PF12349.3 CEP11845.1 - 1e-28 99.7 4.4 4e-28 97.8 3.1 2.1 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation WD40 PF00400.27 CEP11845.1 - 2.1e-14 52.7 13.1 0.00055 19.7 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Patched PF02460.13 CEP11845.1 - 6.7e-14 50.7 3.0 1.1e-13 50.1 2.1 1.3 1 0 0 1 1 1 1 Patched family Exo_endo_phos PF03372.18 CEP11846.1 - 8.5e-12 45.5 0.0 6.1e-10 39.4 0.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Eapp_C PF10238.4 CEP11846.1 - 3.8 7.4 10.1 0.27 11.1 3.3 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein p450 PF00067.17 CEP11847.1 - 6.1e-74 249.2 0.0 7.8e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arrestin_C PF02752.17 CEP11848.1 - 1.1e-17 64.3 0.9 4.4e-14 52.7 0.2 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP11848.1 - 2.4e-17 63.1 0.0 4.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CEP11848.1 - 0.00038 20.0 0.0 0.00073 19.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like CTK3 PF12243.3 CEP11849.1 - 1e-33 115.9 0.1 1.7e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 CEP11849.1 - 2.5e-16 59.4 7.0 2.5e-16 59.4 4.9 1.7 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DnaB_2 PF07261.6 CEP11849.1 - 0.024 14.2 0.4 0.082 12.5 0.0 2.1 2 0 0 2 2 2 0 Replication initiation and membrane attachment CTD_bind PF04818.8 CEP11849.1 - 0.052 13.8 0.1 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. LRR_4 PF12799.2 CEP11850.1 - 1.4e-24 85.1 32.7 1.6e-05 24.3 0.4 6.4 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP11850.1 - 1.6e-18 66.1 28.5 5.8e-06 25.9 0.2 4.7 3 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.1 CEP11850.1 - 2.9e-13 49.7 12.8 6e-08 32.4 0.6 3.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 CEP11850.1 - 5e-10 37.9 21.9 1.4 9.2 0.0 9.5 9 1 0 10 10 10 4 Leucine Rich Repeat LRR_7 PF13504.1 CEP11850.1 - 9.9e-07 27.9 14.5 31 5.3 0.0 9.0 8 1 1 9 9 9 0 Leucine rich repeat LRR_6 PF13516.1 CEP11850.1 - 0.2 11.8 31.0 3.5 8.0 0.1 8.7 7 3 2 9 9 9 0 Leucine Rich repeat Rogdi_lz PF10259.4 CEP11851.1 - 9.8e-23 80.6 0.4 2.3e-21 76.0 0.3 2.0 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein bZIP_1 PF00170.16 CEP11852.1 - 2.3e-10 40.2 10.1 5.3e-10 39.1 7.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP11852.1 - 5.9e-09 35.6 7.1 5.9e-09 35.6 4.9 2.2 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 CEP11852.1 - 0.029 14.6 5.7 0.086 13.1 3.9 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.4 CEP11852.1 - 0.032 14.2 3.1 0.054 13.4 2.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 MbeD_MobD PF04899.7 CEP11852.1 - 0.47 10.3 3.6 0.46 10.4 0.9 2.3 2 1 0 2 2 2 0 MbeD/MobD like DUF972 PF06156.8 CEP11852.1 - 0.59 10.5 4.4 0.53 10.6 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) CASP_C PF08172.7 CEP11852.1 - 0.7 8.8 10.2 2.4 7.0 3.3 2.3 2 0 0 2 2 2 0 CASP C terminal GPI-anchored PF10342.4 CEP11853.1 - 1.2e-07 32.1 1.3 2.2e-07 31.2 0.9 1.4 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CEP11853.1 - 0.0003 20.3 0.1 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) RCR PF12273.3 CEP11853.1 - 0.0032 18.0 0.0 0.004 17.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red VirB8 PF04335.8 CEP11853.1 - 0.11 12.0 1.1 0.24 10.9 0.0 1.9 2 1 1 3 3 3 0 VirB8 protein SdrG_C_C PF10425.4 CEP11853.1 - 0.12 12.3 0.1 6.6 6.6 0.0 2.1 1 1 1 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin HTH_29 PF13551.1 CEP11854.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP11854.1 - 0.00025 21.7 0.0 0.00051 20.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 CEP11854.1 - 0.00049 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.1 CEP11854.1 - 0.00061 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP11854.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 CEP11854.1 - 0.019 14.7 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_psq PF05225.11 CEP11854.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DDE_3 PF13358.1 CEP11854.1 - 0.073 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease DNA_pol_lambd_f PF10391.4 CEP11854.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Fmp27_WPPW PF10359.4 CEP11855.1 - 0.032 12.6 4.3 0.73 8.1 0.1 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain p450 PF00067.17 CEP11856.1 - 8.2e-75 252.0 0.4 2.3e-72 243.9 0.2 2.0 1 1 1 2 2 2 2 Cytochrome P450 PfkB PF00294.19 CEP11857.1 - 6.2e-15 55.1 0.0 1.1e-14 54.3 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CEP11857.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Peptidase_C48 PF02902.14 CEP11858.1 - 4.5e-43 147.3 1.0 6.3e-43 146.9 0.7 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RNA_pol_Rpb2_6 PF00562.23 CEP11859.1 - 2.8e-129 431.2 0.0 4.2e-129 430.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CEP11859.1 - 2e-67 226.0 0.1 3e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CEP11859.1 - 7.8e-48 162.4 0.0 1.5e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CEP11859.1 - 5.9e-32 109.7 0.0 2.4e-31 107.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CEP11859.1 - 2.6e-26 91.2 0.1 5.2e-26 90.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CEP11859.1 - 8e-23 79.9 0.1 1.6e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CEP11859.1 - 5.8e-21 74.1 0.6 1.3e-20 73.0 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 UPF0542 PF15086.1 CEP11860.1 - 0.036 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF2254 PF10011.4 CEP11860.1 - 0.096 11.1 1.2 0.25 9.7 0.8 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF3357 PF11837.3 CEP11860.1 - 0.59 10.0 0.0 0.59 10.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF3397 PF11877.3 CEP11860.1 - 4.8 7.1 13.2 1.9 8.5 4.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3397) DUF1765 PF08578.5 CEP11861.1 - 6.4e-20 71.4 5.0 2e-19 69.9 3.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) bZIP_1 PF00170.16 CEP11861.1 - 2e-09 37.2 6.9 2e-09 37.2 4.8 2.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP11861.1 - 1.8e-08 34.0 9.4 1.8e-08 34.0 6.5 4.1 4 1 1 5 5 5 1 Basic region leucine zipper Sel1 PF08238.7 CEP11862.1 - 1.3e-23 82.8 9.6 1.6e-08 34.9 1.1 4.3 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.1 CEP11862.1 - 0.001 19.6 0.4 0.49 11.1 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP11862.1 - 0.027 14.9 0.3 37 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 CEP11862.1 - 1.5 8.6 0.0 1.5 8.6 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11862.1 - 4.7 7.2 8.9 20 5.2 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP11862.1 - 9.6 6.0 0.0 9.6 6.0 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat Spt20 PF12090.3 CEP11863.1 - 4.2e-29 101.2 0.1 4.2e-29 101.2 0.1 9.9 3 2 0 3 3 3 1 Spt20 family LMBR1 PF04791.11 CEP11863.1 - 0.38 9.2 0.0 0.38 9.2 0.0 4.4 2 2 1 3 3 3 0 LMBR1-like membrane protein FCH PF00611.18 CEP11864.1 - 1.4e-11 44.3 1.6 1.4e-11 44.3 1.1 4.2 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CEP11864.1 - 4.3e-08 32.4 1.6 9.3e-08 31.3 1.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP11864.1 - 2.5e-06 26.9 0.1 4.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP11864.1 - 0.0028 17.1 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ATG_C PF09333.6 CEP11864.1 - 0.0046 17.0 1.9 0.0083 16.2 0.2 2.3 2 0 0 2 2 2 1 ATG C terminal domain DUF1409 PF07197.7 CEP11864.1 - 0.028 14.4 0.9 0.095 12.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) YEATS PF03366.11 CEP11865.1 - 1.1e-36 124.4 0.9 1.7e-36 123.7 0.6 1.3 1 0 0 1 1 1 1 YEATS family LSM PF01423.17 CEP11866.1 - 2.2e-20 71.9 0.2 2.4e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 CEP11866.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) CLPTM1 PF05602.7 CEP11867.1 - 2e-125 418.9 0.2 4.4e-125 417.8 0.1 1.5 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) 2TM PF13239.1 CEP11867.1 - 0.012 15.6 2.6 0.044 13.8 1.8 2.0 1 0 0 1 1 1 0 2TM domain PQ-loop PF04193.9 CEP11867.1 - 0.036 13.6 0.3 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 PQ loop repeat AAA PF00004.24 CEP11868.1 - 6e-43 146.2 0.0 1.6e-42 144.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CEP11868.1 - 1.9e-28 98.1 0.1 1.7e-26 91.8 0.1 3.3 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CEP11868.1 - 1.7e-19 69.4 4.0 1.7e-19 69.4 2.8 2.3 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 CEP11868.1 - 1.5e-05 25.1 0.3 0.0015 18.6 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CEP11868.1 - 1.6e-05 25.6 0.1 8.7e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CEP11868.1 - 1.9e-05 24.4 0.0 9.8e-05 22.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CEP11868.1 - 7.6e-05 22.6 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEP11868.1 - 8.5e-05 21.7 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CEP11868.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 CEP11868.1 - 0.0002 20.8 0.1 0.3 10.4 0.1 2.9 1 1 1 2 2 2 2 AAA domain RNA_helicase PF00910.17 CEP11868.1 - 0.00022 21.3 0.2 0.019 15.1 0.0 3.3 3 1 1 4 4 4 1 RNA helicase AAA_16 PF13191.1 CEP11868.1 - 0.00024 21.1 0.0 0.00088 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CEP11868.1 - 0.00031 19.7 0.0 0.0043 16.0 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CEP11868.1 - 0.00032 20.6 0.1 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CEP11868.1 - 0.0007 18.4 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CEP11868.1 - 0.0017 18.2 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 CEP11868.1 - 0.0036 17.6 0.4 0.018 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CEP11868.1 - 0.004 16.7 0.1 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CEP11868.1 - 0.0045 16.7 0.5 0.45 10.1 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 CEP11868.1 - 0.02 14.7 0.1 0.26 11.0 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Torsin PF06309.6 CEP11868.1 - 0.022 14.6 0.0 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 Torsin Mg_chelatase PF01078.16 CEP11868.1 - 0.027 13.6 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CEP11868.1 - 0.03 14.0 0.0 0.091 12.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 CEP11868.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CEP11868.1 - 0.05 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 CEP11868.1 - 0.05 12.6 0.1 0.3 10.1 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin KaiC PF06745.8 CEP11868.1 - 0.071 12.2 0.0 4.8 6.2 0.0 2.4 1 1 1 2 2 2 0 KaiC Dymeclin PF09742.4 CEP11868.1 - 0.076 11.1 0.5 0.11 10.6 0.3 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Sigma54_activat PF00158.21 CEP11868.1 - 0.081 12.3 0.0 0.23 10.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CEP11868.1 - 0.088 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 CEP11868.1 - 0.092 12.3 0.0 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 NACHT domain EF-1_beta_acid PF10587.4 CEP11868.1 - 0.12 12.5 2.1 0.45 10.6 0.3 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region HORMA PF02301.13 CEP11869.1 - 6.2e-24 84.6 0.1 7.3e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 CEP11869.1 - 0.003 17.0 0.1 0.0044 16.4 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 SPX PF03105.14 CEP11871.1 - 0.031 14.0 10.7 0.038 13.7 7.4 1.1 1 0 0 1 1 1 0 SPX domain TraF_2 PF13729.1 CEP11871.1 - 0.1 11.3 5.6 0.14 10.9 3.9 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF2967 PF11179.3 CEP11871.1 - 0.18 11.2 7.5 0.27 10.6 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF2681 PF10883.3 CEP11871.1 - 0.35 11.0 21.0 0.19 11.9 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4407 PF14362.1 CEP11871.1 - 1.2 8.0 13.9 1.5 7.6 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FLO_LFY PF01698.11 CEP11871.1 - 1.2 7.9 8.4 1.4 7.6 5.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 CEP11871.1 - 1.3 8.7 8.6 1.6 8.4 6.0 1.2 1 0 0 1 1 1 0 DDHD domain ABC2_membrane_3 PF12698.2 CEP11871.1 - 2.1 7.2 11.2 2.6 7.0 7.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Suf PF05843.9 CEP11871.1 - 2.5 7.7 12.7 3.2 7.3 8.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0020 PF01170.13 CEP11871.1 - 2.5 7.6 5.8 54 3.3 4.1 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Alpha_GJ PF03229.8 CEP11872.1 - 6.7 7.0 11.6 13 6.1 8.1 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Rab_eff_C PF04698.7 CEP11873.1 - 0.0057 14.8 0.0 0.0062 14.7 0.0 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus RNA_pol_Rpb4 PF03874.11 CEP11873.1 - 0.047 13.6 0.4 0.047 13.6 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb4 GNVR PF13807.1 CEP11873.1 - 0.11 12.2 0.3 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase rve PF00665.21 CEP11874.1 - 5.3e-17 62.0 0.0 8.5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP11875.1 - 8.3e-15 54.7 0.1 1.1e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3_N PF09440.5 CEP11876.1 - 2e-46 157.4 4.5 2e-46 157.4 3.1 2.5 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CEP11876.1 - 1.6e-15 57.3 0.7 3e-14 53.2 0.1 2.5 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CEP11876.1 - 0.0052 16.5 4.4 0.0052 16.5 0.1 2.7 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 CEP11876.1 - 0.014 14.8 0.4 0.028 13.8 0.0 1.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 DUF2683 PF10884.3 CEP11876.1 - 0.019 14.9 2.1 0.24 11.3 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) B3 PF02362.16 CEP11876.1 - 0.086 12.4 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 B3 DNA binding domain MFS_2 PF13347.1 CEP11877.1 - 1.4e-07 30.3 30.9 5.1e-07 28.4 21.4 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein DUF485 PF04341.7 CEP11877.1 - 0.016 14.9 0.2 0.016 14.9 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function, DUF485 Peptidase_C7 PF01830.13 CEP11877.1 - 0.055 12.6 0.1 1.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Peptidase C7 family DUF3169 PF11368.3 CEP11877.1 - 0.081 12.1 0.1 0.081 12.1 0.1 3.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3169) Pyr_redox_2 PF07992.9 CEP11878.1 - 2.4e-44 151.6 0.0 5.1e-44 150.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CEP11878.1 - 1.3e-41 141.0 0.3 2.2e-40 137.1 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CEP11878.1 - 2.9e-19 69.2 11.2 1.5e-17 63.7 1.3 3.7 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP11878.1 - 1.2e-12 47.7 6.2 3.5e-11 42.8 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 CEP11878.1 - 6.9e-12 44.9 5.9 1.2e-10 40.8 0.5 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CEP11878.1 - 2.4e-10 40.8 1.0 6.4e-06 26.3 0.2 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CEP11878.1 - 2.3e-09 36.6 16.1 1.6e-07 30.5 0.8 4.6 3 1 2 5 5 5 2 FAD binding domain Thi4 PF01946.12 CEP11878.1 - 3.7e-09 36.0 2.6 5e-06 25.7 0.0 2.6 2 1 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 CEP11878.1 - 3.2e-06 25.9 13.6 8.6e-05 21.1 0.4 4.1 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_8 PF13450.1 CEP11878.1 - 3.9e-06 26.8 4.9 0.00099 19.0 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CEP11878.1 - 4.7e-06 25.9 9.5 0.012 14.6 0.2 3.4 3 1 0 3 3 3 3 FAD binding domain DAO PF01266.19 CEP11878.1 - 8.3e-05 21.6 15.8 0.0035 16.2 0.1 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CEP11878.1 - 0.00029 19.8 0.2 0.26 10.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 CEP11878.1 - 0.0023 17.5 2.5 0.012 15.1 0.3 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CEP11878.1 - 0.0073 15.9 5.9 0.01 15.4 0.5 2.8 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CEP11878.1 - 0.052 12.9 3.1 0.087 12.1 0.2 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 CEP11878.1 - 0.15 12.3 1.2 8.2 6.7 0.2 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 CEP11878.1 - 0.73 8.6 7.3 0.58 9.0 0.1 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein Skp1_POZ PF03931.10 CEP11879.1 - 8.2e-16 57.8 0.0 2.2e-15 56.4 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CEP11879.1 - 0.0052 16.7 0.0 0.0079 16.1 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain ESSS PF10183.4 CEP11882.1 - 1.2e-16 60.9 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Oligomerisation PF02410.10 CEP11886.1 - 9.6e-24 83.3 0.0 1.8e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Oligomerisation domain Bromodomain PF00439.20 CEP11887.1 - 4.9e-19 68.0 0.4 1.6e-18 66.3 0.1 2.1 2 0 0 2 2 2 1 Bromodomain YEATS PF03366.11 CEP11888.1 - 6.4e-22 77.0 0.4 1.6e-21 75.7 0.3 1.7 1 0 0 1 1 1 1 YEATS family RasGEF PF00617.14 CEP11889.1 - 6.3e-15 55.3 0.4 1.2e-14 54.4 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain DUF883 PF05957.8 CEP11889.1 - 0.045 14.1 0.1 0.18 12.2 0.1 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) tRNA-synt_1g PF09334.6 CEP11890.1 - 1.4e-123 412.4 0.4 2.1e-123 411.8 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CEP11890.1 - 2.3e-27 95.2 6.4 1.1e-12 46.8 0.0 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CEP11890.1 - 1.5e-13 50.5 1.0 3.6e-08 32.8 0.3 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CEP11890.1 - 8.8e-08 32.0 0.2 2.2e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA MT0933_antitox PF14013.1 CEP11890.1 - 0.034 14.2 0.3 0.72 10.0 0.1 2.4 2 0 0 2 2 2 0 MT0933-like antitoxin protein DALR_1 PF05746.10 CEP11890.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 DALR anticodon binding domain F-box-like PF12937.2 CEP11891.1 - 5.6e-05 22.7 0.2 0.0025 17.5 0.1 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP11891.1 - 0.018 14.6 0.0 0.21 11.2 0.0 2.7 2 0 0 2 2 2 0 F-box domain LRR_7 PF13504.1 CEP11891.1 - 0.12 12.6 2.0 47 4.8 0.0 5.7 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CEP11891.1 - 4 7.7 11.9 1.3e+02 3.0 0.1 6.4 7 0 0 7 7 7 0 Leucine Rich repeat TPR_1 PF00515.23 CEP11893.1 - 9.8e-13 47.1 0.2 7.3e-05 22.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat PB1 PF00564.19 CEP11893.1 - 2e-11 43.3 1.3 4.6e-11 42.2 0.9 1.6 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.1 CEP11893.1 - 6.9e-11 41.6 0.3 1.7e-08 33.9 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CEP11893.1 - 1.7e-09 36.8 0.1 0.019 14.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP11893.1 - 0.00045 20.0 0.4 0.021 14.7 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11893.1 - 0.0076 15.9 1.5 4.2 7.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP11893.1 - 0.015 15.4 0.0 0.15 12.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ubiquitin_2 PF14560.1 CEP11893.1 - 0.068 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Phage_Gp19 PF09355.5 CEP11893.1 - 0.095 12.5 0.2 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 Pkinase PF00069.20 CEP11894.1 - 2.8e-58 197.0 0.0 1.1e-57 195.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11894.1 - 2.1e-27 95.8 0.0 3.2e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CEP11894.1 - 5.6e-06 26.7 1.1 5.6e-06 26.7 0.8 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEP11894.1 - 0.0056 15.6 0.0 0.018 14.0 0.0 1.8 1 0 0 1 1 1 1 Kinase-like PX PF00787.19 CEP11894.1 - 0.021 14.6 4.3 0.23 11.2 3.0 2.7 1 1 0 1 1 1 0 PX domain Fumerase_C PF05683.7 CEP11894.1 - 0.052 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Fumarase C-terminus DNA_pol_A_exo1 PF01612.15 CEP11895.1 - 1.4e-12 47.4 0.0 4.7e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease HA2 PF04408.18 CEP11897.1 - 1.9e-20 72.7 0.0 1.9e-20 72.7 0.0 2.8 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEP11897.1 - 1.2e-12 47.5 0.1 3.3e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CEP11897.1 - 4.8e-08 32.8 1.3 8.8e-08 31.9 0.1 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold A_thal_3526 PF09713.5 CEP11897.1 - 0.02 15.0 0.1 0.065 13.3 0.0 2.0 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Pantoate_ligase PF02569.10 CEP11898.1 - 1.9e-85 286.0 0.0 2.8e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase EF-hand_7 PF13499.1 CEP11898.1 - 0.0073 16.4 1.6 0.066 13.3 0.1 3.0 3 1 0 3 3 3 1 EF-hand domain pair FAD_binding_3 PF01494.14 CEP11899.1 - 1.2e-27 96.9 0.0 1.5e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEP11899.1 - 7.1e-12 44.8 3.3 3.6e-06 26.1 1.7 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CEP11899.1 - 1.4e-07 31.8 1.7 0.00019 21.7 1.8 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP11899.1 - 1e-06 28.6 0.3 2.4e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEP11899.1 - 1.4e-06 27.4 3.6 2.1e-06 26.8 2.0 1.6 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 CEP11899.1 - 1e-05 24.3 0.5 0.012 14.2 0.6 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.2 CEP11899.1 - 3.4e-05 23.1 0.1 7.3e-05 22.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEP11899.1 - 4.1e-05 23.5 0.6 0.00013 21.8 0.5 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CEP11899.1 - 0.00021 20.5 1.8 0.017 14.2 0.3 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 CEP11899.1 - 0.00026 19.6 1.6 0.00068 18.2 0.8 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 CEP11899.1 - 0.00031 19.7 0.6 0.0042 16.0 0.4 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 CEP11899.1 - 0.0004 19.3 1.7 0.00042 19.3 0.5 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CEP11899.1 - 0.015 15.3 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 CEP11899.1 - 0.016 14.9 0.0 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 Rossmann-like domain Thi4 PF01946.12 CEP11899.1 - 0.057 12.4 1.8 0.1 11.6 1.3 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 CEP11899.1 - 0.13 12.5 0.4 0.31 11.3 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Cupin_2 PF07883.6 CEP11900.1 - 4.6e-21 74.0 1.0 1.5e-17 62.8 0.2 2.5 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CEP11900.1 - 2.3e-06 27.1 0.0 0.023 14.1 0.0 2.2 1 1 1 2 2 2 2 Cupin AraC_binding PF02311.14 CEP11900.1 - 8.6e-06 25.4 0.4 5.6e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.7 CEP11900.1 - 7.7e-05 21.9 0.0 0.046 13.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MFS_1 PF07690.11 CEP11901.1 - 1e-35 123.1 39.1 1.1e-35 122.9 26.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GFA PF04828.9 CEP11902.1 - 3.2e-16 59.0 2.6 4.8e-16 58.4 1.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3133 PF11331.3 CEP11902.1 - 0.029 13.9 1.5 0.29 10.7 1.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) DUF3716 PF12511.3 CEP11902.1 - 0.059 12.9 6.8 2.1 8.0 4.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) Fungal_trans PF04082.13 CEP11903.1 - 7.6e-35 120.0 0.0 1.8e-34 118.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP11903.1 - 4.1e-06 26.6 9.5 1.1e-05 25.2 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.13 CEP11904.1 - 2.4e-58 197.1 0.0 3.2e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PPR_2 PF13041.1 CEP11905.1 - 2.2e-42 142.8 3.2 4.1e-10 39.4 0.1 7.3 4 2 4 8 8 8 6 PPR repeat family PPR_3 PF13812.1 CEP11905.1 - 3.4e-33 111.1 0.9 6.1e-06 26.0 0.0 9.1 9 0 0 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.15 CEP11905.1 - 7.6e-31 103.9 1.3 1.6e-07 30.8 0.0 8.4 9 0 0 9 9 9 5 PPR repeat PPR_1 PF12854.2 CEP11905.1 - 6.5e-21 73.5 1.0 1.6e-06 27.4 0.0 7.4 9 1 0 9 9 9 4 PPR repeat Apc3 PF12895.2 CEP11905.1 - 0.00055 20.0 0.0 1 9.5 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 RPM2 PF08579.6 CEP11905.1 - 0.006 16.7 4.6 1.1 9.3 0.3 4.6 3 1 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) Vps39_1 PF10366.4 CEP11905.1 - 0.0079 16.2 1.3 0.071 13.1 0.0 3.0 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 BTAD PF03704.12 CEP11905.1 - 0.05 13.9 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_12 PF13424.1 CEP11905.1 - 0.073 13.0 0.1 0.74 9.7 0.0 3.3 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP11905.1 - 0.11 12.3 0.0 2.1 8.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.24 CEP11906.1 - 3.3e-41 140.5 0.2 2.6e-40 137.6 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP11906.1 - 1.8e-26 91.7 0.1 3.6e-24 84.4 0.2 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CEP11906.1 - 0.0031 16.6 0.0 0.036 13.1 0.0 2.6 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit LRR_4 PF12799.2 CEP11906.1 - 0.05 13.2 1.2 4.3 7.0 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP11906.1 - 0.45 10.3 6.4 3 7.6 0.2 3.9 3 0 0 3 3 3 0 Leucine rich repeat CNH PF00780.17 CEP11907.1 - 3.5e-08 33.2 0.2 0.013 14.9 0.1 3.2 3 0 0 3 3 3 3 CNH domain Lactamase_B PF00753.22 CEP11908.1 - 1.5e-17 63.8 1.9 5.4e-17 62.0 1.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CEP11908.1 - 4.2e-06 26.4 1.7 8.5e-06 25.4 1.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEP11908.1 - 0.00078 19.1 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Kelch_3 PF13415.1 CEP11909.1 - 2.2e-11 43.5 15.9 0.006 16.7 0.3 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP11909.1 - 2.7e-09 36.6 22.2 5.6e-05 22.8 0.1 6.3 5 2 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP11909.1 - 6.6e-09 35.5 15.0 0.056 13.6 0.2 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.10 CEP11909.1 - 2.4e-08 33.4 5.2 1.1e-05 25.0 0.0 5.2 5 1 0 5 5 5 1 Kelch motif Herpes_gE PF02480.11 CEP11909.1 - 0.0063 14.8 0.0 0.01 14.1 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_1 PF01344.20 CEP11909.1 - 0.0064 16.0 3.4 2.9 7.5 0.3 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CEP11909.1 - 0.019 14.9 9.8 2.5 8.1 0.1 4.2 4 0 0 4 4 4 0 Kelch motif Podoplanin PF05808.6 CEP11909.1 - 0.019 14.5 0.7 0.041 13.4 0.0 1.8 2 0 0 2 2 2 0 Podoplanin VSP PF03302.8 CEP11909.1 - 0.047 12.3 0.2 0.08 11.5 0.1 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4366 PF14283.1 CEP11909.1 - 0.16 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DEAD PF00270.24 CEP11910.1 - 5.1e-39 133.4 0.0 1.2e-38 132.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP11910.1 - 4.2e-24 84.2 0.1 2.7e-23 81.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CEP11910.1 - 7.3e-05 21.7 0.0 0.00017 20.4 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CEP11910.1 - 0.074 13.2 2.9 0.35 11.0 1.0 2.8 2 1 0 2 2 2 0 AAA domain EI24 PF07264.6 CEP11911.1 - 4.5e-20 72.0 12.6 6.3e-20 71.5 7.9 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) F-box-like_2 PF13013.1 CEP11912.1 - 0.039 13.6 0.6 0.066 12.9 0.4 1.3 1 0 0 1 1 1 0 F-box-like domain Coprogen_oxidas PF01218.13 CEP11914.1 - 1.5e-121 404.5 0.0 1.7e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SRF-TF PF00319.13 CEP11915.1 - 1.6e-20 72.0 0.0 2.3e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Suf PF05843.9 CEP11915.1 - 4.4 6.9 32.0 4 7.0 11.8 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zf-RVT PF13966.1 CEP11916.1 - 0.00037 20.7 1.1 0.00081 19.6 0.8 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 CEP11917.1 - 3.9e-18 65.5 0.0 6.7e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kinesin PF00225.18 CEP11919.1 - 6.5e-33 113.8 4.1 9.9e-31 106.6 2.9 2.2 1 1 0 1 1 1 1 Kinesin motor domain MEDS PF14417.1 CEP11919.1 - 0.0016 17.5 0.2 0.01 14.8 0.1 2.0 2 0 0 2 2 2 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Cep57_CLD_2 PF14197.1 CEP11919.1 - 0.0021 17.9 1.0 0.0021 17.9 0.7 2.3 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 Hydrolase_6 PF13344.1 CEP11919.1 - 0.088 12.7 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ERF PF04404.7 CEP11922.1 - 0.057 12.9 3.3 0.18 11.3 0.4 2.2 1 1 1 2 2 2 0 ERF superfamily DUF4642 PF15484.1 CEP11922.1 - 0.1 12.5 1.0 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) Usp PF00582.21 CEP11923.1 - 6.2e-22 78.3 0.6 4.1e-21 75.6 0.4 1.9 1 1 0 1 1 1 1 Universal stress protein family Pkinase PF00069.20 CEP11924.1 - 4e-70 235.9 0.0 6.9e-70 235.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11924.1 - 2e-49 168.0 0.0 3.4e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CEP11924.1 - 2e-21 76.1 0.9 3.1e-20 72.3 0.0 2.9 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 CEP11924.1 - 7.1e-06 25.1 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP11924.1 - 0.0054 15.8 0.1 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP11924.1 - 0.028 14.1 0.0 1.1 8.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 CEP11924.1 - 0.048 12.8 0.0 0.15 11.2 0.0 1.9 1 0 0 1 1 1 0 DSHCT (NUC185) domain Ribosomal_60s PF00428.14 CEP11924.1 - 0.79 10.1 4.4 1.7 9.0 3.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein HhH-GPD PF00730.20 CEP11925.1 - 2.4e-14 53.5 0.0 4.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 CEP11925.1 - 0.031 14.4 0.7 0.078 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) RuvB_C PF05491.8 CEP11925.1 - 0.12 12.0 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB C-terminus UCH PF00443.24 CEP11926.1 - 3.4e-65 219.8 0.0 7e-65 218.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ATP-synt_C PF00137.16 CEP11926.1 - 8e-28 96.1 31.2 2.7e-17 62.4 8.1 2.4 2 0 0 2 2 2 2 ATP synthase subunit C UCH_1 PF13423.1 CEP11926.1 - 1.1e-22 80.8 0.0 4.6e-22 78.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 CEP11926.1 - 4.4e-13 49.1 1.9 7.8e-13 48.3 1.3 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.15 CEP11926.1 - 1.9e-05 24.9 0.0 4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF3164 PF11363.3 CEP11927.1 - 0.053 12.9 0.2 0.084 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) CENP-B_dimeris PF09026.5 CEP11927.1 - 0.18 12.0 15.2 0.53 10.5 8.4 2.7 2 1 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 CEP11927.1 - 9.1 6.5 13.5 0.4 10.8 2.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) COX16 PF14138.1 CEP11927.1 - 9.2 6.5 10.0 0.35 11.0 0.8 2.6 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein COX16 Epimerase PF01370.16 CEP11928.1 - 3.8e-42 144.3 0.0 5.1e-41 140.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CEP11928.1 - 2.1e-05 23.5 0.0 0.00047 19.1 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CEP11928.1 - 0.007 15.2 0.4 0.29 9.9 0.3 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Rad50_zn_hook PF04423.9 CEP11930.1 - 0.00057 19.3 0.2 0.0018 17.7 0.1 1.9 1 0 0 1 1 1 1 Rad50 zinc hook motif UIM PF02809.15 CEP11930.1 - 0.00076 18.8 1.0 0.00076 18.8 0.7 2.4 3 0 0 3 3 3 1 Ubiquitin interaction motif Prok-RING_4 PF14447.1 CEP11930.1 - 0.084 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C2H2_4 PF13894.1 CEP11930.1 - 0.2 12.0 0.3 0.41 11.0 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger ELMO_CED12 PF04727.8 CEP11931.1 - 3.7e-40 137.2 2.0 3.7e-40 137.2 1.4 1.4 2 0 0 2 2 2 1 ELMO/CED-12 family DUF1115 PF06544.7 CEP11932.1 - 5e-19 68.2 0.1 1.2e-18 66.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Sec1 PF00995.18 CEP11933.1 - 2.5e-129 432.5 0.0 2.9e-129 432.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GATA PF00320.22 CEP11934.1 - 1e-30 104.7 15.3 6.1e-16 57.4 2.8 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 CEP11934.1 - 1.2e-10 40.7 1.0 3.1e-10 39.4 0.7 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.5 CEP11934.1 - 0.0029 17.5 1.5 0.69 9.9 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 CEP11934.1 - 0.004 16.4 5.0 0.45 9.8 0.3 2.7 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 CEP11934.1 - 0.038 13.8 9.1 4.5 7.1 1.0 3.2 1 1 2 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.1 CEP11934.1 - 0.12 11.6 7.7 1 8.6 0.1 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-CHY PF05495.7 CEP11934.1 - 0.25 11.5 3.1 2.5 8.2 0.1 2.6 1 1 2 3 3 3 0 CHY zinc finger FYVE PF01363.16 CEP11934.1 - 0.31 10.9 4.1 0.76 9.7 2.1 2.2 2 1 0 2 2 2 0 FYVE zinc finger RRN7 PF11781.3 CEP11934.1 - 1.2 8.7 6.0 12 5.5 0.2 3.1 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 A2L_zn_ribbon PF08792.5 CEP11934.1 - 1.3 8.6 6.1 16 5.0 0.1 3.5 2 1 1 3 3 3 0 A2L zinc ribbon domain zf-B_box PF00643.19 CEP11934.1 - 1.8 8.5 8.2 44 4.0 0.0 3.9 3 1 1 4 4 4 0 B-box zinc finger eIF-5_eIF-2B PF01873.12 CEP11934.1 - 10 5.8 9.8 11 5.6 0.5 3.1 3 0 0 3 3 3 0 Domain found in IF2B/IF5 AMP-binding PF00501.23 CEP11935.1 - 3.1e-43 147.7 0.0 6.6e-43 146.6 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CEP11935.1 - 8.2e-37 126.4 0.0 2.9e-35 121.3 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 CEP11935.1 - 3.8e-08 33.4 0.2 1.2e-07 31.8 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 CEP11935.1 - 4.6e-05 22.9 0.0 0.00024 20.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fe_hyd_SSU PF02256.12 CEP11935.1 - 0.038 14.0 0.0 0.56 10.2 0.0 2.7 2 0 0 2 2 2 0 Iron hydrogenase small subunit TPR_11 PF13414.1 CEP11936.1 - 3.1e-31 106.8 5.9 6.6e-12 44.8 0.0 5.4 3 2 2 5 5 5 5 TPR repeat DnaJ PF00226.26 CEP11936.1 - 3.8e-22 77.8 4.9 3.8e-22 77.8 3.4 3.2 3 0 0 3 3 3 1 DnaJ domain TPR_16 PF13432.1 CEP11936.1 - 1.9e-21 76.1 0.3 9.8e-06 26.0 0.1 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CEP11936.1 - 4.6e-21 72.9 5.6 0.014 15.2 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 CEP11936.1 - 2.4e-19 68.0 9.2 0.033 13.8 0.1 7.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_9 PF13371.1 CEP11936.1 - 4.1e-18 64.9 0.3 0.00011 22.0 0.0 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11936.1 - 5e-15 54.0 6.3 0.0036 16.9 0.1 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CEP11936.1 - 4.4e-14 52.5 9.3 4.3e-05 23.7 0.0 5.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP11936.1 - 3.2e-13 49.0 3.0 0.0047 17.4 0.0 5.8 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEP11936.1 - 1e-11 44.0 4.9 0.025 14.7 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CEP11936.1 - 2.5e-07 30.7 14.2 0.02 15.0 0.3 5.0 4 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CEP11936.1 - 3.7e-07 29.9 6.4 0.38 10.7 0.1 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP11936.1 - 9.7e-07 28.8 5.7 0.28 11.7 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 CEP11936.1 - 0.0033 17.4 8.0 0.072 13.2 0.0 4.7 2 2 2 4 4 4 1 Tetratricopeptide repeat HemY_N PF07219.8 CEP11936.1 - 0.012 15.1 1.0 0.25 10.9 0.0 3.0 3 0 0 3 3 3 0 HemY protein N-terminus Fis1_TPR_C PF14853.1 CEP11936.1 - 0.014 15.2 2.1 16 5.4 0.1 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CEP11936.1 - 0.016 15.4 0.9 0.32 11.2 0.4 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_7 PF13176.1 CEP11936.1 - 0.031 14.0 3.9 38 4.4 0.0 5.4 6 1 1 7 7 6 0 Tetratricopeptide repeat CotJB PF12652.2 CEP11936.1 - 0.089 12.8 2.8 0.16 12.0 0.0 2.8 3 0 0 3 3 2 0 CotJB protein Enkurin PF13864.1 CEP11936.1 - 2.4 8.4 10.5 1.2 9.4 1.9 3.4 2 1 1 3 3 3 0 Calmodulin-binding CAP PF00188.21 CEP11937.1 - 2e-25 89.6 5.0 2.8e-25 89.1 3.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PRKCSH PF07915.8 CEP11938.1 - 5.5e-15 55.9 2.8 5.5e-15 55.9 2.0 3.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF1690 PF07956.6 CEP11938.1 - 1.9e-10 40.8 8.7 1.9e-10 40.8 6.0 2.9 3 0 0 3 3 3 1 Protein of Unknown function (DUF1690) Cas_Csa5 PF09702.5 CEP11938.1 - 0.19 11.7 2.0 0.27 11.3 0.2 2.2 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Med15 PF09606.5 CEP11938.1 - 7.5 4.6 34.2 11 4.1 23.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hira PF07569.6 CEP11939.1 - 1.8e-50 171.1 0.1 1.8e-50 171.1 0.1 2.1 3 0 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.27 CEP11939.1 - 1.2e-40 135.8 15.7 2.7e-08 33.3 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 CEP11939.1 - 4.8e-09 35.5 0.1 1.4e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 HIRA B motif PQQ_3 PF13570.1 CEP11939.1 - 0.13 12.5 0.8 16 5.9 0.1 3.1 2 0 0 2 2 2 0 PQQ-like domain PD40 PF07676.7 CEP11939.1 - 1.9 8.2 6.3 5.5 6.7 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat LRR_8 PF13855.1 CEP11940.1 - 5.5e-17 61.2 40.9 5e-10 38.9 3.3 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CEP11940.1 - 5.4e-13 48.2 27.5 2.1e-05 24.0 1.6 4.3 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP11940.1 - 2.3e-09 35.9 21.4 0.11 12.5 0.0 7.1 6 0 0 6 6 6 4 Leucine Rich Repeat Birna_VP4 PF01768.11 CEP11940.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein LRR_6 PF13516.1 CEP11940.1 - 0.014 15.4 12.9 3.2 8.0 0.1 5.2 4 2 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 CEP11940.1 - 0.027 14.6 24.9 0.93 9.9 0.1 6.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 CEP11940.1 - 0.26 10.8 3.7 0.92 9.0 0.2 2.0 1 1 0 1 1 1 0 Leucine-rich repeat MAPEG PF01124.13 CEP11941.1 - 0.00014 21.5 5.9 0.00023 20.7 4.1 1.4 1 1 0 1 1 1 1 MAPEG family BTP PF05232.7 CEP11941.1 - 0.033 13.9 1.1 0.033 13.9 0.8 2.6 3 0 0 3 3 3 0 Bacterial Transmembrane Pair family Aminotran_5 PF00266.14 CEP11942.1 - 3.2e-30 105.1 0.0 4.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CEP11942.1 - 8.8e-06 24.2 0.2 1.7e-05 23.2 0.1 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 CEP11942.1 - 3.2e-05 23.7 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain ELFV_dehydrog PF00208.16 CEP11942.1 - 0.022 14.3 0.1 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase KR PF08659.5 CEP11942.1 - 0.034 13.8 0.2 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 KR domain Transketolase_C PF02780.15 CEP11942.1 - 0.065 13.1 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain adh_short PF00106.20 CEP11942.1 - 0.074 12.9 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Pyr_redox_2 PF07992.9 CEP11943.1 - 2.2e-19 70.1 0.0 3.8e-19 69.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP11943.1 - 1.5e-13 50.8 0.5 8.7e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP11943.1 - 4.5e-08 33.4 0.2 4.9e-05 23.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEP11943.1 - 1.1e-06 27.8 0.2 3.5e-05 22.8 0.0 2.2 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CEP11943.1 - 2.5e-06 27.3 3.9 0.022 14.5 0.0 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 CEP11943.1 - 4.8e-06 25.7 0.1 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CEP11943.1 - 4.6e-05 22.5 0.3 0.28 10.0 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 CEP11943.1 - 8.9e-05 22.6 0.1 0.005 17.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 CEP11943.1 - 0.0001 21.1 0.3 0.011 14.3 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.13 CEP11943.1 - 0.00013 21.9 0.5 0.042 13.8 0.0 2.8 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_8 PF13450.1 CEP11943.1 - 0.00048 20.0 1.2 0.02 14.8 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Malic_M PF03949.10 CEP11943.1 - 0.033 13.7 0.1 0.52 9.8 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain DUF4147 PF13660.1 CEP11943.1 - 0.072 12.1 0.8 4.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Lipase_GDSL_2 PF13472.1 CEP11943.1 - 0.074 13.1 0.0 0.25 11.4 0.0 1.8 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.14 CEP11943.1 - 0.091 11.7 2.1 6.9 5.6 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.17 CEP11943.1 - 0.11 11.3 1.7 17 4.1 1.2 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Pkinase PF00069.20 CEP11944.1 - 9.8e-23 80.6 0.1 1.7e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11944.1 - 2e-20 72.9 0.4 7.5e-20 71.0 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 CEP11944.1 - 0.00017 20.9 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 SAP domain RhoGEF PF00621.15 CEP11945.1 - 8.3e-34 117.0 4.4 8.3e-34 117.0 3.0 2.7 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.24 CEP11945.1 - 4.2e-08 33.3 0.9 6.1e-07 29.6 0.0 2.9 2 0 0 2 2 2 1 PH domain FKS1_dom1 PF14288.1 CEP11945.1 - 0.16 11.8 9.4 2.6 7.9 0.2 3.6 3 0 0 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3808 PF10300.4 CEP11946.1 - 1.3e-55 188.8 11.5 3.5e-30 104.9 0.3 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) TPR_2 PF07719.12 CEP11946.1 - 0.084 12.8 8.6 0.14 12.1 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat WIYLD PF10440.4 CEP11946.1 - 0.09 12.7 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain TPR_6 PF13174.1 CEP11946.1 - 0.17 12.3 9.1 0.49 10.9 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP11946.1 - 0.5 10.3 8.2 26 4.8 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11946.1 - 0.57 10.0 3.9 6.7 6.7 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP11946.1 - 0.69 9.6 0.0 0.69 9.6 0.0 4.7 5 1 1 6 6 6 0 TPR repeat TPR_1 PF00515.23 CEP11946.1 - 5 6.8 6.2 3.3 7.4 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DDE_3 PF13358.1 CEP11947.1 - 2e-23 82.7 0.1 1.6e-22 79.8 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Metallophos PF00149.23 CEP11948.1 - 4.4e-47 160.0 0.6 5.7e-47 159.7 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP11948.1 - 0.0034 17.2 0.0 0.0052 16.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain U3_assoc_6 PF08640.6 CEP11948.1 - 0.1 12.3 0.3 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 DUF3759 PF12585.3 CEP11949.1 - 6.2e-36 122.1 8.9 7.2e-36 121.9 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SRP40_C PF05022.7 CEP11949.1 - 0.074 13.5 0.9 0.12 12.9 0.4 1.6 1 1 1 2 2 2 0 SRP40, C-terminal domain DUF739 PF05339.6 CEP11950.1 - 0.017 14.8 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF739) AA_permease_2 PF13520.1 CEP11951.1 - 4e-54 183.7 52.2 2.6e-49 167.9 23.1 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 CEP11951.1 - 1.1e-20 73.4 52.5 3.5e-19 68.4 36.4 2.7 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.8 CEP11952.1 - 6.6e-27 94.4 0.0 1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEP11952.1 - 5.5e-13 48.2 0.2 9.7e-13 47.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Glyco_transf_41 PF13844.1 CEP11953.1 - 1.6e-110 369.2 2.2 1.7e-55 187.8 0.1 3.9 2 1 0 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.1 CEP11953.1 - 8.6e-22 76.5 2.8 5.4e-08 32.3 0.1 4.8 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 CEP11953.1 - 1.6e-20 71.7 4.7 6.4e-05 22.3 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP11953.1 - 6.4e-17 60.0 3.1 0.00099 18.8 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEP11953.1 - 5.3e-15 55.1 6.6 3.8e-06 26.7 0.0 5.2 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CEP11953.1 - 8.2e-14 50.5 10.4 0.0014 18.6 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEP11953.1 - 7e-13 47.3 4.0 0.00014 21.3 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP11953.1 - 2.4e-11 43.2 0.1 0.0076 16.7 0.0 5.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP11953.1 - 4.8e-09 36.6 4.5 2.2e-05 24.9 0.0 4.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP11953.1 - 9.4e-08 31.7 14.6 0.017 15.0 0.1 5.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEP11953.1 - 6.3e-06 25.5 2.4 0.31 10.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP11953.1 - 0.00015 21.9 2.8 4.5 7.9 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CEP11953.1 - 0.0026 17.5 0.7 0.013 15.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEP11953.1 - 0.09 13.1 11.0 0.61 10.4 0.0 4.5 4 2 1 6 6 4 0 Tetratricopeptide repeat Flavodoxin_1 PF00258.20 CEP11953.1 - 0.13 12.3 0.0 7.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin Glyco_transf_22 PF03901.12 CEP11954.1 - 3.9e-64 217.1 17.8 5.2e-41 141.0 4.1 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family zf-C2H2 PF00096.21 CEP11955.1 - 1.4e-15 56.6 28.8 4.9e-07 29.7 3.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP11955.1 - 5.6e-12 45.3 18.6 7.5e-09 35.4 0.8 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP11955.1 - 2.5e-10 39.9 25.3 0.0021 18.2 1.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP11955.1 - 0.0012 18.9 14.6 0.96 9.6 0.8 3.8 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEP11955.1 - 0.0039 17.0 9.6 2.1 8.3 0.2 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 CEP11955.1 - 0.091 12.5 8.8 1.1 9.0 2.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-met PF12874.2 CEP11955.1 - 0.097 12.9 10.7 7.6 6.8 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CEP11955.1 - 0.38 10.4 16.0 0.5 10.0 0.8 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 CEP11955.1 - 0.71 9.8 8.4 9.8 6.2 0.3 3.3 2 1 1 3 3 3 0 Zinc ribbon domain Mu-like_Com PF10122.4 CEP11955.1 - 0.71 8.9 4.4 1.6 7.8 0.3 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Zn_ribbon_recom PF13408.1 CEP11955.1 - 2.3 8.5 10.8 0.59 10.4 3.2 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF4544 PF15077.1 CEP11956.1 - 0.046 13.2 1.2 0.08 12.4 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Paramyxo_C PF01692.13 CEP11956.1 - 1.7 8.2 6.4 0.57 9.7 1.3 2.0 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c DSPc PF00782.15 CEP11958.1 - 8.6e-12 44.7 0.0 1.8e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CEP11958.1 - 0.0035 17.3 0.0 0.0087 16.1 0.0 1.7 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CEP11958.1 - 0.012 14.9 0.0 0.033 13.5 0.0 1.5 1 1 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.7 CEP11958.1 - 0.016 14.6 0.1 0.025 14.0 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.7 CEP11958.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Cellulase PF00150.13 CEP11959.1 - 6.2e-20 71.5 0.0 6.9e-13 48.4 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) ABC_tran PF00005.22 CEP11960.1 - 1e-33 116.5 0.3 1.3e-18 67.6 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CEP11960.1 - 6.4e-12 46.0 0.0 0.0038 17.2 0.0 3.4 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 CEP11960.1 - 3.4e-08 33.0 0.1 0.075 12.2 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CEP11960.1 - 6.3e-08 33.4 0.0 0.0012 19.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEP11960.1 - 7.9e-08 31.7 0.1 0.0085 15.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 CEP11960.1 - 1.3e-07 31.7 0.0 0.015 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CEP11960.1 - 1.4e-07 31.7 0.6 0.053 13.7 0.0 4.5 5 0 0 5 5 3 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CEP11960.1 - 3.4e-07 29.6 0.0 0.00077 18.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP11960.1 - 1e-06 28.9 0.0 0.036 14.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 CEP11960.1 - 1.1e-06 29.1 0.0 0.085 13.3 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein MMR_HSR1 PF01926.18 CEP11960.1 - 2.3e-06 27.5 0.0 0.015 15.2 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase NACHT PF05729.7 CEP11960.1 - 4.3e-06 26.4 0.1 0.065 12.8 0.0 3.5 3 1 0 3 3 3 2 NACHT domain AAA_15 PF13175.1 CEP11960.1 - 9.6e-06 24.8 0.0 0.65 8.9 0.1 3.6 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 CEP11960.1 - 1.9e-05 24.8 0.2 0.43 10.7 0.0 3.1 3 0 0 3 3 2 2 RNA helicase MobB PF03205.9 CEP11960.1 - 4.1e-05 23.3 0.0 0.13 11.9 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CEP11960.1 - 6e-05 21.9 1.1 0.09 11.5 0.0 2.7 3 0 0 3 3 2 2 ArgK protein AAA_18 PF13238.1 CEP11960.1 - 7.3e-05 23.0 0.1 0.11 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEP11960.1 - 0.00018 21.0 0.0 0.36 10.2 0.0 2.7 3 0 0 3 3 3 2 AAA-like domain PduV-EutP PF10662.4 CEP11960.1 - 0.00019 20.9 0.1 0.46 9.9 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Chromo PF00385.19 CEP11960.1 - 0.00028 20.4 2.3 0.00063 19.3 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_16 PF13191.1 CEP11960.1 - 0.00036 20.5 1.8 0.066 13.1 0.0 3.2 4 0 0 4 4 3 1 AAA ATPase domain DUF815 PF05673.8 CEP11960.1 - 0.00044 19.2 0.1 0.37 9.6 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CEP11960.1 - 0.00047 20.0 0.0 0.46 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CEP11960.1 - 0.00056 19.7 0.0 0.2 11.4 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 CEP11960.1 - 0.00067 19.2 0.0 0.24 10.8 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 CEP11960.1 - 0.0007 19.5 0.0 0.76 9.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CEP11960.1 - 0.0012 19.2 10.4 0.063 13.5 0.4 3.3 4 1 0 4 4 2 2 AAA domain Arch_ATPase PF01637.13 CEP11960.1 - 0.002 17.8 1.0 1.6 8.4 0.0 3.5 4 0 0 4 4 3 1 Archaeal ATPase Dynamin_N PF00350.18 CEP11960.1 - 0.0028 17.4 0.0 0.37 10.5 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.1 CEP11960.1 - 0.01 15.4 0.1 1.3 8.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 CEP11960.1 - 0.012 14.7 0.0 2.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MutS_V PF00488.16 CEP11960.1 - 0.017 14.5 0.1 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AAA_25 PF13481.1 CEP11960.1 - 0.02 14.2 0.0 11 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 CEP11960.1 - 0.024 13.5 0.2 1.9 7.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 CEP11960.1 - 0.029 13.8 0.0 0.88 9.0 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PRK PF00485.13 CEP11960.1 - 0.032 13.8 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 CEP11960.1 - 0.032 12.9 0.1 3.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 CEP11960.1 - 0.048 13.3 0.1 4.8 6.8 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 CEP11960.1 - 0.064 13.0 0.1 6.5 6.5 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain IstB_IS21 PF01695.12 CEP11960.1 - 0.065 12.6 0.0 14 5.0 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein FeoB_N PF02421.13 CEP11960.1 - 0.075 12.3 0.4 4.9 6.4 0.0 3.2 4 0 0 4 4 2 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 CEP11960.1 - 0.093 12.1 0.8 18 4.7 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_5 PF07728.9 CEP11960.1 - 0.15 11.7 0.5 13 5.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 CEP11960.1 - 0.24 9.7 5.5 3.9 5.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain HEAT PF02985.17 CEP11960.1 - 4.1 7.7 6.4 12 6.2 0.0 4.7 6 0 0 6 6 4 0 HEAT repeat ABC_tran PF00005.22 CEP11961.1 - 3.4e-10 40.3 0.0 3.6e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 CEP11961.1 - 0.0064 16.3 0.0 0.028 14.3 0.0 1.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.11 CEP11963.1 - 2e-24 85.9 39.9 2e-24 85.9 27.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP11963.1 - 1.3e-11 43.7 2.8 1.3e-11 43.7 1.9 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Fimbrial_PilY2 PF14481.1 CEP11963.1 - 0.02 14.2 0.7 0.033 13.6 0.0 1.7 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 DUF4064 PF13273.1 CEP11963.1 - 1.5 8.9 14.4 1.6 8.8 0.0 4.3 4 2 1 5 5 5 0 Protein of unknown function (DUF4064) Lactate_perm PF02652.9 CEP11964.1 - 1e-127 426.8 32.5 2.7e-77 260.4 13.9 2.1 2 0 0 2 2 2 2 L-lactate permease MFS_1 PF07690.11 CEP11965.1 - 2.4e-21 75.8 27.5 1e-20 73.8 19.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily QCR10 PF09796.4 CEP11965.1 - 0.059 13.0 0.1 6 6.6 0.0 3.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF3309 PF11752.3 CEP11965.1 - 0.073 12.8 2.6 7.5 6.4 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3309) RhoGAP PF00620.22 CEP11966.1 - 3.2e-33 114.5 0.2 5.1e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 CEP11966.1 - 1.8e-24 86.3 0.7 6.5e-24 84.5 0.2 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CEP11966.1 - 0.00037 20.0 0.3 0.0012 18.3 0.1 2.0 3 0 0 3 3 3 1 CRAL/TRIO domain Acetyltransf_11 PF13720.1 CEP11966.1 - 0.062 13.5 0.1 0.5 10.6 0.0 2.4 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ApoB100_C PF12491.3 CEP11966.1 - 0.14 11.8 2.7 0.23 11.1 0.0 2.7 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal tRNA-synt_2 PF00152.15 CEP11967.1 - 1.7e-83 280.1 0.8 2.9e-83 279.4 0.5 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CEP11967.1 - 1.7e-05 24.5 0.4 3.6e-05 23.5 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CEP11967.1 - 0.0078 15.4 0.5 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) POM121 PF15229.1 CEP11967.1 - 0.26 10.6 3.4 0.37 10.1 2.4 1.2 1 0 0 1 1 1 0 POM121 family PS_Dcarbxylase PF02666.10 CEP11968.1 - 1.4e-59 200.7 0.0 2.4e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PRA1 PF03208.14 CEP11968.1 - 1.6e-29 102.2 2.9 2.8e-29 101.4 2.0 1.4 1 0 0 1 1 1 1 PRA1 family protein C2 PF00168.25 CEP11968.1 - 7.8e-23 80.1 0.1 2.8e-15 55.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain WTF PF03303.8 CEP11968.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 WTF protein Y_phosphatase2 PF03162.8 CEP11969.1 - 1.1e-15 57.4 0.0 2.7e-12 46.3 0.0 2.0 1 1 1 2 2 2 2 Tyrosine phosphatase family WD40 PF00400.27 CEP11970.1 - 5.6e-42 140.1 17.4 1.5e-10 40.5 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CEP11970.1 - 2.9e-07 30.3 11.7 0.03 14.0 0.7 4.5 3 1 2 5 5 5 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 CEP11970.1 - 0.48 8.1 5.8 1.7 6.3 0.1 2.1 2 0 0 2 2 2 0 IKI3 family CPSase_L_D2 PF02786.12 CEP11971.1 - 3.7e-69 232.2 0.1 7e-69 231.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 CEP11971.1 - 2e-31 108.1 0.0 4.9e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 CEP11971.1 - 4.9e-29 100.6 0.1 1.4e-28 99.1 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CEP11971.1 - 6.6e-20 71.6 0.0 3.2e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CEP11971.1 - 1e-15 57.1 2.3 2.2e-14 52.8 1.5 2.9 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CEP11971.1 - 3.7e-12 46.0 0.0 7.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 CEP11971.1 - 7.8e-11 41.2 0.1 2e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CEP11971.1 - 1.8e-09 37.2 0.0 3.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CEP11971.1 - 3.9e-08 32.8 1.8 6.9e-05 22.4 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 CEP11971.1 - 5.3e-08 32.8 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CEP11971.1 - 1.8e-05 24.1 0.5 0.00078 18.8 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CEP11971.1 - 0.00023 21.4 5.1 0.024 14.9 0.0 3.8 4 0 0 4 4 3 1 HlyD family secretion protein RnfC_N PF13375.1 CEP11971.1 - 0.0014 18.2 1.9 0.0098 15.5 0.3 2.6 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.6 CEP11971.1 - 0.0034 16.6 0.1 0.0068 15.6 0.1 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) TraK PF06586.6 CEP11971.1 - 0.004 16.3 1.3 0.019 14.1 0.4 2.4 3 0 0 3 3 3 1 TraK protein HlyD_2 PF12700.2 CEP11971.1 - 0.037 13.1 0.2 0.17 11.0 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein Pkinase PF00069.20 CEP11972.1 - 1.4e-76 257.0 0.0 1.9e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11972.1 - 1.7e-36 125.6 0.0 2.1e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP11972.1 - 5e-05 22.4 0.0 0.00031 19.8 0.0 2.0 1 1 0 2 2 2 1 Kinase-like PACT_coil_coil PF10495.4 CEP11972.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein YrbL-PhoP_reg PF10707.4 CEP11972.1 - 0.0095 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CEP11972.1 - 0.025 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CEP11972.1 - 0.049 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_23 PF13476.1 CEP11973.1 - 0.014 15.7 12.7 0.027 14.7 3.4 2.2 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 CEP11974.1 - 4e-11 42.5 11.8 2.5e-05 24.3 2.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP11974.1 - 2.8e-08 33.6 13.6 3.6e-05 23.8 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP11974.1 - 1.8e-05 24.7 10.6 0.0074 16.5 1.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CEP11974.1 - 0.0036 17.3 2.0 0.006 16.6 1.4 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 CEP11974.1 - 0.0052 16.4 3.0 0.24 11.1 0.5 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 CEP11974.1 - 0.033 14.3 0.9 0.033 14.3 0.6 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP11974.1 - 0.17 12.1 4.7 0.24 11.6 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 CEP11974.1 - 0.18 11.6 0.2 0.18 11.6 0.1 3.1 3 0 0 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 CEP11974.1 - 3 7.7 4.7 8.3 6.3 3.3 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PDZ_1 PF12812.2 CEP11975.1 - 1.6e-33 114.3 0.0 1e-23 83.0 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 CEP11975.1 - 3.1e-16 59.0 0.3 0.00017 21.4 0.0 5.1 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 CEP11975.1 - 2.8e-12 46.6 0.0 1.3e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 CEP11975.1 - 3.1e-11 43.3 0.7 0.00046 20.3 0.0 4.1 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 CEP11975.1 - 0.00067 19.3 0.1 1 8.8 0.0 4.0 4 0 0 4 4 4 1 Trypsin Tricorn_PDZ PF14685.1 CEP11975.1 - 0.0014 18.3 0.2 4.2 7.2 0.0 3.6 3 0 0 3 3 3 2 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 CEP11975.1 - 0.04 12.3 0.3 0.14 10.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.16 CEP11975.1 - 0.064 12.6 0.3 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S3 PF00944.14 CEP11975.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Alphavirus core protein DUF31 PF01732.11 CEP11975.1 - 0.24 10.6 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Pkinase PF00069.20 CEP11976.1 - 1.3e-64 217.9 0.0 2e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP11976.1 - 8.7e-49 165.9 0.0 1.5e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP11976.1 - 6.5e-08 31.8 0.0 9.1e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.1 CEP11976.1 - 1.8e-07 31.0 0.1 4.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 RA PF00788.18 CEP11976.1 - 0.02 15.3 0.0 0.052 14.0 0.0 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain APH PF01636.18 CEP11976.1 - 0.068 12.8 0.0 0.37 10.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CEP11976.1 - 0.091 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCM PF00493.18 CEP11977.1 - 8e-128 425.8 1.4 1.1e-127 425.4 1.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CEP11977.1 - 1.9e-22 79.9 0.1 1.9e-21 76.7 0.0 2.6 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CEP11977.1 - 3e-08 33.0 0.1 1.5e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEP11977.1 - 0.0013 18.3 0.0 0.0069 15.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CEP11977.1 - 0.01 15.2 0.0 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 CEP11977.1 - 0.029 14.0 0.0 0.15 11.8 0.0 2.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PRP1_N PF06424.7 CEP11977.1 - 0.32 11.2 8.6 1.3 9.3 3.3 2.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal NOA36 PF06524.7 CEP11977.1 - 4.9 6.3 5.8 8.8 5.4 4.0 1.3 1 0 0 1 1 1 0 NOA36 protein DDE_Tnp_1_7 PF13843.1 CEP11978.1 - 1e-42 146.4 0.0 1.9e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 Transposase IS4 RhoGAP PF00620.22 CEP11978.1 - 1.2e-38 132.0 0.7 3.5e-38 130.6 0.5 1.8 1 0 0 1 1 1 1 RhoGAP domain HAMP PF00672.20 CEP11979.1 - 5.2e-172 558.3 67.8 4.6e-08 33.1 0.0 23.9 23 1 1 24 24 24 21 HAMP domain HATPase_c PF02518.21 CEP11979.1 - 7.9e-30 102.8 1.2 8.5e-29 99.5 0.2 3.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEP11979.1 - 3e-25 88.4 0.4 2.4e-23 82.2 0.1 2.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 CEP11979.1 - 5.8e-19 67.8 1.5 1e-17 63.8 0.4 3.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.12 CEP11979.1 - 1.8e-13 50.0 16.4 31 4.4 0.0 18.1 19 0 0 19 19 19 0 Helix-turn-helix domain, rpiR family Pox_A_type_inc PF04508.7 CEP11979.1 - 5.4e-09 35.0 5.0 0.21 11.4 0.0 9.0 9 0 0 9 9 9 1 Viral A-type inclusion protein repeat HMG_box PF00505.14 CEP11979.1 - 1.1e-07 32.0 0.0 1e+02 3.2 0.0 10.0 13 0 0 13 13 13 0 HMG (high mobility group) box SpoIIID PF12116.3 CEP11979.1 - 1.5e-05 24.8 29.0 17 5.4 0.0 14.8 17 0 0 17 17 17 0 Stage III sporulation protein D NAAA-beta PF15508.1 CEP11979.1 - 0.033 14.5 6.5 16 5.8 0.1 8.9 9 1 1 10 10 10 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase W2 PF02020.13 CEP11980.1 - 1.5e-20 72.9 8.4 1.5e-20 72.9 5.8 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 CEP11980.1 - 7.5e-11 41.0 12.3 7.3e-05 22.0 0.1 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CEP11980.1 - 3.5e-08 32.8 2.8 6.8e-07 28.7 0.2 2.5 1 1 1 2 2 2 1 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 CEP11980.1 - 2.6e-05 23.6 0.0 5.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CEP11980.1 - 0.011 15.8 0.0 0.12 12.4 0.0 2.3 3 0 0 3 3 3 0 MobA-like NTP transferase domain Fucokinase PF07959.7 CEP11980.1 - 0.076 11.5 0.3 0.12 10.8 0.2 1.2 1 0 0 1 1 1 0 L-fucokinase TFIIS_C PF01096.13 CEP11981.1 - 3.4e-17 61.7 2.2 3.4e-17 61.7 1.5 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CEP11981.1 - 1.5e-05 24.6 16.3 0.00083 18.9 3.1 3.1 2 1 1 3 3 3 2 RNA polymerases M/15 Kd subunit DUF523 PF04463.7 CEP11981.1 - 0.00016 21.4 4.4 0.00038 20.2 3.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF523) Lar_restr_allev PF14354.1 CEP11981.1 - 0.0021 18.3 0.4 0.0021 18.3 0.3 2.9 2 1 0 2 2 2 1 Restriction alleviation protein Lar DZR PF12773.2 CEP11981.1 - 0.0027 17.4 10.2 0.078 12.8 0.4 3.1 2 1 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CEP11981.1 - 0.0074 15.7 18.9 0.18 11.3 0.1 3.7 4 0 0 4 4 4 2 zinc-ribbon domain Baculo_LEF5_C PF11792.3 CEP11981.1 - 0.018 14.4 1.2 0.018 14.4 0.9 3.1 4 0 0 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.2 CEP11981.1 - 0.022 14.5 2.3 0.022 14.5 1.6 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DNA_ligase_ZBD PF03119.11 CEP11981.1 - 0.031 13.9 5.4 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.1 CEP11981.1 - 0.041 13.0 16.3 0.36 10.0 0.5 3.5 3 1 1 4 4 4 0 zinc-ribbon domain zf-IS66 PF13005.2 CEP11981.1 - 0.047 13.6 11.5 5.8 6.9 0.1 4.0 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Terminase_GpA PF05876.7 CEP11981.1 - 0.056 11.7 5.8 0.011 14.1 2.0 1.4 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.7 CEP11981.1 - 0.075 12.3 11.3 0.96 8.8 1.6 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding GATA PF00320.22 CEP11981.1 - 0.077 12.3 8.9 0.77 9.1 0.1 3.0 3 0 0 3 3 3 0 GATA zinc finger IBR PF01485.16 CEP11981.1 - 0.09 12.6 10.4 0.23 11.3 0.2 2.7 2 1 0 2 2 2 0 IBR domain NOB1_Zn_bind PF08772.6 CEP11981.1 - 0.17 11.7 10.7 2.1 8.2 0.1 3.2 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Prok-RING_1 PF14446.1 CEP11981.1 - 0.2 11.3 10.5 0.24 11.1 1.4 3.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-CSL PF05207.8 CEP11981.1 - 0.3 10.6 0.2 0.3 10.6 0.2 3.5 2 2 1 3 3 3 0 CSL zinc finger DUF2387 PF09526.5 CEP11981.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.7 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) DUF164 PF02591.10 CEP11981.1 - 0.38 10.6 6.9 3.6 7.4 0.0 3.7 4 0 0 4 4 4 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.5 CEP11981.1 - 0.39 10.6 17.3 2.2 8.2 0.1 4.2 3 1 1 4 4 4 0 Zinc ribbon domain PolC_DP2 PF03833.8 CEP11981.1 - 0.44 8.1 5.7 0.065 10.9 1.3 1.5 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 A2L_zn_ribbon PF08792.5 CEP11981.1 - 0.51 9.8 16.7 5 6.7 0.6 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain ArfGap PF01412.13 CEP11981.1 - 0.53 10.0 7.9 0.74 9.6 4.7 1.8 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.6 CEP11981.1 - 0.61 9.7 9.8 3 7.5 2.7 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-TFIIB PF13453.1 CEP11981.1 - 0.65 9.2 9.7 0.12 11.6 1.1 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-HYPF PF07503.7 CEP11981.1 - 0.69 9.3 0.1 0.69 9.3 0.0 3.6 4 0 0 4 4 3 0 HypF finger Rpr2 PF04032.11 CEP11981.1 - 0.77 9.6 11.1 0.055 13.3 1.9 2.6 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_3 PF14369.1 CEP11981.1 - 0.86 9.6 9.7 19 5.3 0.0 3.5 4 0 0 4 4 3 0 zinc-finger zinc-ribbons_6 PF07191.7 CEP11981.1 - 1.2 8.9 10.2 0.98 9.2 0.3 2.9 2 1 0 2 2 2 0 zinc-ribbons Viral_NABP PF05515.6 CEP11981.1 - 2.4 8.4 5.5 0.5 10.6 1.2 1.8 1 1 1 2 2 2 0 Viral nucleic acid binding HypA PF01155.14 CEP11981.1 - 2.5 7.8 10.6 71 3.1 4.4 3.0 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PHD PF00628.24 CEP11981.1 - 3.3 7.4 11.5 0.48 10.1 0.5 2.6 2 1 0 2 2 2 0 PHD-finger Zn_ribbon_recom PF13408.1 CEP11981.1 - 4.5 7.6 11.1 35 4.7 0.1 3.4 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain Nudix_N_2 PF14803.1 CEP11981.1 - 6.2 6.6 15.4 26 4.5 0.1 3.9 3 1 0 3 3 3 0 Nudix N-terminal Elf1 PF05129.8 CEP11981.1 - 9.6 5.9 13.2 0.067 12.8 1.9 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Dynamitin PF04912.9 CEP11982.1 - 5.4e-68 229.5 31.7 5.7e-49 166.9 14.3 2.0 2 0 0 2 2 2 2 Dynamitin DUF1451 PF07295.6 CEP11982.1 - 2.3 8.0 9.8 0.062 13.0 1.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1451) Herpes_Helicase PF02689.9 CEP11983.1 - 0.0044 14.8 0.1 0.0048 14.7 0.1 1.0 1 0 0 1 1 1 1 Helicase Amidohydro_4 PF13147.1 CEP11985.1 - 4e-21 76.2 4.6 4.5e-15 56.4 0.1 3.9 4 0 0 4 4 4 2 Amidohydrolase Amidohydro_1 PF01979.15 CEP11985.1 - 2.3e-16 60.4 0.1 1.5e-15 57.6 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 CEP11985.1 - 1e-15 57.2 4.4 1.2e-11 44.2 0.5 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CEP11985.1 - 3.7e-13 49.4 0.2 2.8e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF3455 PF11937.3 CEP11987.1 - 2.2e-08 34.2 0.3 5.4e-08 32.9 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) EF-hand_1 PF00036.27 CEP11988.1 - 1.7e-35 117.5 14.8 1.3e-09 36.6 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEP11988.1 - 4e-32 110.1 5.8 1e-17 63.9 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP11988.1 - 3.9e-28 94.7 7.0 9.9e-08 31.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CEP11988.1 - 1e-27 95.4 15.7 3.4e-14 52.1 1.8 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CEP11988.1 - 3.9e-27 92.3 13.7 2.4e-07 29.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CEP11988.1 - 2.7e-11 43.2 0.0 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CEP11988.1 - 2e-08 34.2 0.3 1.6e-05 24.9 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEP11988.1 - 2.3e-08 33.7 2.7 0.0036 17.0 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 CEP11988.1 - 0.0036 17.0 0.8 0.33 10.6 0.1 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB UPF0154 PF03672.8 CEP11988.1 - 0.01 15.4 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF21 PF01595.15 CEP11988.1 - 0.18 11.1 0.0 9 5.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 Phos_pyr_kin PF08543.7 CEP11989.1 - 1.1e-85 286.7 1.4 1.6e-85 286.2 1.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CEP11989.1 - 1.2e-38 132.9 0.1 1.5e-37 129.4 0.0 2.1 1 1 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CEP11989.1 - 3.9e-07 29.4 0.1 6.2e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 CEP11989.1 - 0.0021 17.3 0.1 0.0038 16.5 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate kinase SMC_N PF02463.14 CEP11990.1 - 8.6e-28 97.0 0.0 2.1e-27 95.8 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEP11990.1 - 2.4e-17 63.9 6.9 2.4e-17 63.9 4.8 6.2 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 CEP11990.1 - 6.5e-07 29.6 11.9 0.002 18.1 0.5 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CEP11990.1 - 2.3e-06 27.0 0.1 5.4e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CEP11990.1 - 2.3e-05 23.6 18.0 2.3e-05 23.6 12.5 3.8 2 2 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 CEP11990.1 - 0.00022 21.0 0.1 0.0036 17.1 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 CEP11990.1 - 0.072 13.3 0.1 0.072 13.3 0.1 5.4 4 2 1 5 5 5 0 ABC transporter AAA_16 PF13191.1 CEP11990.1 - 0.69 9.8 0.0 0.69 9.8 0.0 3.6 2 1 0 2 2 2 0 AAA ATPase domain Spc7 PF08317.6 CEP11990.1 - 2.6 6.6 66.3 0.47 9.0 13.1 3.6 2 1 1 3 3 3 0 Spc7 kinetochore protein FliJ PF02050.11 CEP11990.1 - 3.5 7.6 61.9 0.29 11.2 5.2 6.7 4 2 2 6 6 6 0 Flagellar FliJ protein GPI-anchored PF10342.4 CEP11991.1 - 5.1e-12 46.0 0.2 5.1e-12 46.0 0.1 1.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glycos_transf_1 PF00534.15 CEP11992.1 - 1.6e-28 99.2 0.0 3.5e-27 94.8 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CEP11992.1 - 1.9e-07 31.0 0.0 3.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CEP11992.1 - 3.1e-06 27.4 0.0 4.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CEP11992.1 - 4.4e-06 26.8 0.0 9.9e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CEP11992.1 - 4.3e-05 23.6 0.0 0.00071 19.7 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 DNA_pol_B PF00136.16 CEP11993.1 - 7.9e-118 394.1 0.0 7.9e-118 394.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CEP11993.1 - 1.4e-52 177.8 9.4 1.4e-52 177.8 6.5 1.8 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CEP11993.1 - 4.4e-40 137.5 0.0 7.7e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CEP11993.1 - 0.00013 21.6 8.6 0.00013 21.6 6.0 2.5 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal FA_desaturase PF00487.19 CEP11993.1 - 0.031 13.7 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Fatty acid desaturase DegS PF05384.6 CEP11994.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Sensor protein DegS Usp PF00582.21 CEP11995.1 - 6.3e-17 62.0 0.0 1.3e-16 61.0 0.0 1.6 2 0 0 2 2 2 1 Universal stress protein family Ribosomal_S26e PF01283.14 CEP11997.1 - 2.8e-51 172.5 8.4 3.8e-51 172.1 5.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_10 PF13237.1 CEP11997.1 - 0.34 10.7 3.6 0.86 9.4 0.8 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain cNMP_binding PF00027.24 CEP11999.1 - 3.6e-43 145.2 0.3 2.3e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CEP11999.1 - 6.8e-12 44.6 1.5 1.4e-11 43.6 1.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Nucleoplasmin PF03066.10 CEP11999.1 - 0.34 10.4 3.1 0.59 9.6 2.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Septin PF00735.13 CEP12000.1 - 2.2e-113 377.9 1.2 3.3e-113 377.4 0.8 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEP12000.1 - 3.7e-08 33.3 0.0 8.9e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP12000.1 - 7.6e-08 32.0 2.9 9.2e-07 28.4 0.1 2.8 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEP12000.1 - 1.6e-07 30.6 0.1 4e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CEP12000.1 - 1.8e-05 25.1 0.2 0.00021 21.7 0.1 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CEP12000.1 - 0.00038 20.6 0.9 0.0019 18.3 0.1 2.3 1 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CEP12000.1 - 0.00079 18.9 0.1 0.0019 17.7 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Ras PF00071.17 CEP12000.1 - 0.00092 18.6 0.1 0.0025 17.2 0.0 1.8 1 0 0 1 1 1 1 Ras family AIG1 PF04548.11 CEP12000.1 - 0.0017 17.5 0.2 0.0045 16.1 0.1 1.7 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CEP12000.1 - 0.0017 18.2 8.6 0.17 11.6 0.0 3.3 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.8 CEP12000.1 - 0.0039 16.0 0.1 0.01 14.6 0.1 1.7 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.1 CEP12000.1 - 0.0046 16.8 0.3 0.033 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 CEP12000.1 - 0.0046 16.4 0.1 0.0087 15.5 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CEP12000.1 - 0.0047 17.0 0.0 0.018 15.2 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 CEP12000.1 - 0.0097 15.5 0.1 0.023 14.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CEP12000.1 - 0.015 15.0 1.1 0.57 9.8 0.2 2.5 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 CEP12000.1 - 0.015 15.2 0.4 0.06 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 CEP12000.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 CEP12000.1 - 0.037 13.5 1.9 0.98 8.9 0.3 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CEP12000.1 - 0.04 13.4 1.4 1.1 8.7 0.1 3.1 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein MobB PF03205.9 CEP12000.1 - 0.054 13.1 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Adaptin_binding PF10199.4 CEP12000.1 - 0.057 13.6 4.4 0.1 12.9 3.1 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 NACHT PF05729.7 CEP12000.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 CEP12000.1 - 0.069 13.4 0.0 0.069 13.4 0.0 2.1 2 1 0 2 2 1 0 ABC transporter PRK PF00485.13 CEP12000.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 CEP12000.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CEP12000.1 - 0.4 10.9 18.0 16 5.7 12.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEP12000.1 - 0.97 9.7 6.1 0.26 11.5 0.1 2.8 2 2 1 3 3 3 0 AAA domain AAA_17 PF13207.1 CEP12000.1 - 2.3 9.0 4.5 0.85 10.4 0.2 2.5 2 2 0 2 2 2 0 AAA domain APG6 PF04111.7 CEP12000.1 - 2.6 6.9 13.9 4.5 6.2 9.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 KaiC PF06745.8 CEP12000.1 - 3.6 6.6 7.3 2.8 6.9 0.1 2.9 3 0 0 3 3 3 0 KaiC DUF87 PF01935.12 CEP12000.1 - 6.1 6.5 8.8 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 PH PF00169.24 CEP12003.1 - 4.4e-40 136.0 6.0 3.5e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 CEP12003.1 - 3.7e-17 62.5 11.5 2.8e-09 37.1 0.4 4.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 CEP12003.1 - 6e-13 48.6 6.2 3e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 CEP12003.1 - 7.8e-13 48.2 8.2 6.4e-06 26.0 2.6 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 CEP12003.1 - 2.3e-08 34.1 9.6 0.0079 16.3 4.1 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain Myosin_TH1 PF06017.8 CEP12003.1 - 0.021 14.1 3.2 1.8 7.7 0.2 2.6 3 0 0 3 3 3 0 Myosin tail PH_4 PF15404.1 CEP12003.1 - 0.024 14.1 2.8 0.14 11.6 0.4 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain DUF1743 PF08489.6 CEP12003.1 - 0.026 14.2 0.2 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) PH_7 PF15408.1 CEP12003.1 - 0.062 13.1 2.2 4 7.3 0.2 3.1 2 2 0 2 2 2 0 Pleckstrin homology domain DUF2236 PF09995.4 CEP12004.1 - 0.00018 20.9 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Bax1-I PF01027.15 CEP12007.1 - 2.2e-49 167.8 31.9 2.5e-49 167.6 22.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3325 PF11804.3 CEP12007.1 - 4 7.4 11.2 0.5 10.3 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) Acyl-CoA_dh_1 PF00441.19 CEP12008.1 - 1.6e-31 109.4 0.1 5.7e-31 107.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 CEP12008.1 - 1.5e-21 76.0 0.0 3e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 CEP12008.1 - 1.3e-17 62.9 0.2 3.6e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CEP12008.1 - 8.3e-11 42.4 0.0 3.6e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEP12008.1 - 0.0051 17.0 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 CEP12009.1 - 9.4e-73 244.5 0.0 1.3e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12009.1 - 8.3e-37 126.6 0.0 1.1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CEP12009.1 - 6.5e-16 58.2 0.0 1.5e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 CEP12009.1 - 6.8e-05 22.0 0.1 0.00012 21.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CEP12009.1 - 0.00068 18.6 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CEP12009.1 - 0.0017 17.2 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CEP12009.1 - 0.005 16.6 0.2 0.61 9.7 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Fe-S_assembly PF04384.8 CEP12009.1 - 0.12 12.7 0.2 0.27 11.6 0.2 1.5 1 0 0 1 1 1 0 Iron-sulphur cluster assembly FMO-like PF00743.14 CEP12010.1 - 3.7e-48 164.0 0.0 1.1e-33 116.2 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CEP12010.1 - 2.5e-28 99.5 0.0 7.6e-27 94.6 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEP12010.1 - 2.2e-11 43.2 0.0 3.9e-08 32.6 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CEP12010.1 - 4.9e-10 39.6 0.0 9.1e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP12010.1 - 5.6e-09 35.9 0.8 2.4e-05 24.1 0.2 3.3 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CEP12010.1 - 2.8e-08 33.6 0.0 1.9e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CEP12010.1 - 8.4e-05 21.8 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CEP12010.1 - 0.00016 21.9 0.7 0.084 13.2 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP12010.1 - 0.00085 18.3 1.8 0.2 10.5 0.1 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 CEP12010.1 - 0.0018 18.3 1.7 1.6 8.8 0.1 2.9 3 1 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 CEP12010.1 - 0.012 14.1 0.1 0.07 11.5 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 CEP12010.1 - 0.014 14.2 0.0 0.029 13.2 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 CEP12010.1 - 0.018 14.1 0.7 0.061 12.4 0.0 2.2 3 0 0 3 3 3 0 Thi4 family CPSase_L_chain PF00289.17 CEP12010.1 - 0.022 14.8 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_7 PF13241.1 CEP12010.1 - 0.034 14.4 3.3 4.6 7.5 0.3 3.2 2 2 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.7 CEP12010.1 - 0.074 12.4 0.2 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 CEP12010.1 - 0.085 11.7 0.1 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Semialdhyde_dh PF01118.19 CEP12010.1 - 0.091 13.0 0.0 8 6.7 0.0 3.0 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 CEP12010.1 - 0.094 11.7 0.1 0.27 10.2 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 CEP12010.1 - 0.13 12.0 0.1 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thioredoxin PF00085.15 CEP12011.1 - 1.4e-33 114.6 0.0 3.8e-24 84.3 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CEP12011.1 - 2.6e-11 43.6 0.1 4.6e-05 23.3 0.0 3.8 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEP12011.1 - 1.3e-09 37.9 3.0 0.00015 21.8 0.0 4.9 2 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CEP12011.1 - 3.2e-08 33.7 1.0 5.2e-05 23.3 0.4 3.7 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CEP12011.1 - 0.013 15.5 0.1 0.17 11.8 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.1 CEP12011.1 - 0.013 15.2 0.2 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Ribosomal_S5_C PF03719.10 CEP12012.1 - 0.013 14.7 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Retrotrans_gag PF03732.12 CEP12012.1 - 0.037 14.1 0.0 0.037 14.1 0.0 1.0 1 0 0 1 1 1 0 Retrotransposon gag protein ORC5_C PF14630.1 CEP12013.1 - 0.13 11.6 3.7 1.8 7.9 0.3 2.9 2 1 1 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus MRP-S27 PF10037.4 CEP12013.1 - 0.32 9.8 5.8 0.14 11.0 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 HSCB_C PF07743.8 CEP12013.1 - 0.35 11.3 9.1 0.89 10.0 0.5 3.3 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Baculo_PEP_C PF04513.7 CEP12013.1 - 0.79 9.5 6.0 0.66 9.7 1.8 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_1 PF00078.22 CEP12014.1 - 4.9e-14 52.1 0.1 1.3e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GHMP_kinases_N PF00288.21 CEP12016.1 - 5e-09 36.1 1.4 1e-08 35.1 1.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain tRNA-synt_1c PF00749.16 CEP12017.1 - 7.5e-108 359.9 0.0 7.5e-108 359.9 0.0 3.1 2 1 1 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain DUF1767 PF08585.7 CEP12017.1 - 0.0033 17.6 0.0 0.2 11.9 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) Ribosomal_L7Ae PF01248.21 CEP12018.1 - 2.6e-27 94.1 0.0 2.9e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-RanBP PF00641.13 CEP12019.1 - 3.8e-35 118.6 49.4 7.8e-09 34.4 2.4 5.3 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others RNase_T PF00929.19 CEP12019.1 - 9e-10 39.0 0.0 1.7e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.17 CEP12019.1 - 7.2e-08 31.9 0.0 1.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12019.1 - 3.7e-05 23.6 0.0 8.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12019.1 - 0.015 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 CEP12020.1 - 4.2e-16 59.6 2.0 8.3e-08 32.6 0.2 2.7 2 1 1 3 3 3 2 Exonuclease Sugar_tr PF00083.19 CEP12021.1 - 2.8e-103 345.8 20.2 3.3e-103 345.6 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP12021.1 - 9.2e-26 90.3 34.8 3.1e-17 62.3 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CEP12021.1 - 5.4e-05 21.5 1.2 5.4e-05 21.5 0.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 CEP12021.1 - 0.0033 15.9 0.1 0.0033 15.9 0.1 2.3 3 0 0 3 3 3 1 Reduced folate carrier DUF1228 PF06779.9 CEP12021.1 - 0.28 11.2 11.2 0.23 11.5 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) HNH PF01844.18 CEP12022.1 - 0.0011 18.8 0.7 0.002 17.9 0.5 1.4 1 0 0 1 1 1 1 HNH endonuclease Cu-oxidase_2 PF07731.9 CEP12022.1 - 0.12 11.8 0.2 3.3 7.2 0.1 2.2 2 0 0 2 2 2 0 Multicopper oxidase 6PF2K PF01591.13 CEP12023.1 - 1.3e-71 240.2 0.1 2e-71 239.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEP12023.1 - 1.3e-25 90.3 0.1 4.1e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CEP12023.1 - 3.3e-08 33.5 0.0 6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CEP12023.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CEP12023.1 - 0.00021 22.0 0.0 0.00052 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEP12023.1 - 0.00046 19.3 0.0 0.0011 18.1 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin Peptidase_C58 PF03543.9 CEP12023.1 - 0.088 12.2 0.1 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Ank_5 PF13857.1 CEP12024.1 - 0.00037 20.6 0.2 0.0022 18.2 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEP12024.1 - 0.0032 17.7 0.4 0.0095 16.2 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEP12024.1 - 0.0055 16.4 0.0 0.0055 16.4 0.0 2.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 CEP12024.1 - 0.022 14.9 0.1 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat DUF506 PF04720.7 CEP12024.1 - 0.022 14.3 0.2 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Ank_4 PF13637.1 CEP12024.1 - 0.023 15.2 0.1 0.34 11.4 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF2789 PF10982.3 CEP12024.1 - 0.048 13.6 1.8 0.11 12.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2789) GAF_2 PF13185.1 CEP12025.1 - 1.1e-06 29.2 0.0 2.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 CEP12025.1 - 1.3e-05 25.3 0.0 3.9e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain SH3_9 PF14604.1 CEP12026.1 - 1.4e-08 34.1 0.1 4.5e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CEP12026.1 - 7.4e-06 25.2 0.0 1.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP12026.1 - 9.4e-05 21.8 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF2668 PF10873.3 CEP12026.1 - 0.019 15.1 3.4 0.019 15.1 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Syndecan PF01034.15 CEP12026.1 - 0.084 12.5 1.0 0.16 11.6 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain P2X_receptor PF00864.14 CEP12026.1 - 0.092 11.4 2.1 0.15 10.7 1.4 1.2 1 0 0 1 1 1 0 ATP P2X receptor DUF3959 PF13105.1 CEP12026.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Ribosomal_S21e PF01249.13 CEP12027.1 - 2.6e-39 133.0 0.0 2.8e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF1682 PF07946.9 CEP12028.1 - 3.5e-70 236.4 0.9 4.1e-70 236.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) CBP4 PF07960.6 CEP12029.1 - 9.2e-14 51.1 0.1 9.4e-14 51.1 0.1 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 CEP12029.1 - 0.00029 20.5 0.7 0.0003 20.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4574) HemX PF04375.9 CEP12029.1 - 0.0032 16.1 0.1 0.0033 16.0 0.0 1.0 1 0 0 1 1 1 1 HemX PDEase_I_N PF08499.7 CEP12029.1 - 0.0056 16.5 0.2 0.0077 16.1 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF2959 PF11172.3 CEP12029.1 - 0.077 12.7 1.2 0.088 12.5 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Homeobox PF00046.24 CEP12031.1 - 1.2e-15 56.8 2.5 1.2e-15 56.8 1.7 1.9 2 0 0 2 2 2 1 Homeobox domain DUF4304 PF14137.1 CEP12031.1 - 0.031 14.3 0.3 0.062 13.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) HIRA_B PF09453.5 CEP12031.1 - 0.16 11.5 0.6 0.41 10.2 0.4 1.7 1 0 0 1 1 1 0 HIRA B motif F_actin_cap_B PF01115.12 CEP12032.1 - 9.1e-104 345.9 0.0 1.2e-103 345.4 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Lectin_leg-like PF03388.8 CEP12032.1 - 1.3e-69 233.8 0.0 1.8e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 CEP12032.1 - 0.00017 21.0 0.0 0.2 11.0 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain F-actin_cap_A PF01267.12 CEP12032.1 - 0.0013 17.8 0.1 0.0087 15.1 0.0 2.3 1 1 1 2 2 2 1 F-actin capping protein alpha subunit Sbi-IV PF11621.3 CEP12033.1 - 0.0022 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 C3 binding domain 4 of IgG-bind protein SBI HAMP PF00672.20 CEP12034.1 - 1.5e-25 89.1 4.4 1.3e-09 38.1 0.1 3.6 3 1 1 4 4 4 3 HAMP domain GrpE PF01025.14 CEP12034.1 - 0.0047 16.4 0.0 0.087 12.3 0.0 2.1 1 1 1 2 2 2 1 GrpE GatB_Yqey PF02637.13 CEP12034.1 - 0.01 15.5 2.9 0.55 9.9 0.1 3.0 3 0 0 3 3 3 0 GatB domain HTH_6 PF01418.12 CEP12034.1 - 0.018 14.7 0.4 1.2 8.9 0.0 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain, rpiR family WXG100 PF06013.7 CEP12034.1 - 0.024 14.6 3.1 0.86 9.6 0.1 3.3 2 1 0 3 3 3 0 Proteins of 100 residues with WXG ImcF-related_N PF14331.1 CEP12034.1 - 0.032 13.1 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 ImcF-related N-terminal domain Peptidase_M32 PF02074.10 CEP12034.1 - 0.041 12.5 2.2 2.2 6.8 0.1 2.1 1 1 1 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase SpoIIID PF12116.3 CEP12034.1 - 0.12 12.2 2.8 21 5.1 0.1 3.5 3 1 0 3 3 3 0 Stage III sporulation protein D DUF948 PF06103.6 CEP12034.1 - 0.16 11.8 15.8 11 6.0 2.3 4.5 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) VBS PF08913.5 CEP12034.1 - 0.25 11.5 4.9 4.5 7.5 0.2 2.8 1 1 1 3 3 3 0 Vinculin Binding Site DUF2365 PF10157.4 CEP12034.1 - 0.45 10.3 6.6 35 4.2 0.0 3.8 3 2 0 4 4 4 0 Uncharacterized conserved protein (DUF2365) DASH_Dad2 PF08654.5 CEP12034.1 - 2.4 8.1 10.6 94 3.0 0.2 4.6 4 1 0 4 4 4 0 DASH complex subunit Dad2 HAMP PF00672.20 CEP12037.1 - 8.9e-24 83.4 6.4 3.9e-09 36.5 0.1 4.2 4 1 1 5 5 5 3 HAMP domain Baculo_PEP_C PF04513.7 CEP12037.1 - 6.5e-06 26.0 6.7 0.042 13.6 0.1 3.3 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus bPH_3 PF14470.1 CEP12037.1 - 0.016 15.4 0.8 32 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial PH domain HTH_6 PF01418.12 CEP12037.1 - 0.028 14.1 2.4 21 4.9 0.0 3.8 5 0 0 5 5 5 0 Helix-turn-helix domain, rpiR family Vps52 PF04129.7 CEP12037.1 - 0.045 12.2 0.3 15 3.9 0.0 3.0 3 0 0 3 3 3 0 Vps52 / Sac2 family SpoIIID PF12116.3 CEP12037.1 - 0.09 12.7 0.2 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Stage III sporulation protein D DUF948 PF06103.6 CEP12037.1 - 0.1 12.4 7.9 2.2 8.1 0.4 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) OspD PF03207.8 CEP12037.1 - 0.15 11.2 8.4 2.5 7.1 0.3 3.1 1 1 0 3 3 3 0 Borrelia outer surface protein D (OspD) DUF2365 PF10157.4 CEP12037.1 - 0.49 10.2 6.0 3.1 7.6 0.2 3.6 2 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2365) TMF_TATA_bd PF12325.3 CEP12037.1 - 1.3 8.7 5.8 37 4.0 0.1 3.4 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DASH_Dad2 PF08654.5 CEP12037.1 - 1.7 8.7 6.4 19 5.3 0.1 3.9 3 1 0 4 4 4 0 DASH complex subunit Dad2 rve PF00665.21 CEP12038.1 - 0.003 17.6 0.0 1.7 8.8 0.0 2.4 1 1 1 2 2 2 2 Integrase core domain EIID-AGA PF03613.9 CEP12039.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component Z1 PF10593.4 CEP12039.1 - 0.17 11.0 3.5 0.088 12.0 0.2 1.9 1 1 1 2 2 2 0 Z1 domain COX7C PF02935.11 CEP12041.1 - 5.1e-11 42.1 0.1 1.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Herpes_gE PF02480.11 CEP12041.1 - 0.00085 17.7 0.0 0.0013 17.0 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CEP12041.1 - 0.0096 16.2 0.0 0.033 14.5 0.0 2.0 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.3 CEP12041.1 - 0.017 15.6 0.1 0.23 11.9 0.0 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.6 CEP12041.1 - 0.031 13.9 1.6 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein TMEM154 PF15102.1 CEP12041.1 - 0.033 13.9 0.0 0.033 13.9 0.0 2.5 2 1 0 2 2 2 0 TMEM154 protein family Shisa PF13908.1 CEP12041.1 - 0.049 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Syndecan PF01034.15 CEP12041.1 - 0.077 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Polysacc_deac_1 PF01522.16 CEP12042.1 - 3e-26 91.4 0.2 5.8e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Ank_2 PF12796.2 CEP12043.1 - 7.5e-64 212.0 13.0 7.4e-24 83.9 0.2 4.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CEP12043.1 - 1.1e-43 144.8 11.4 2.3e-06 27.1 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 CEP12043.1 - 1e-38 131.0 7.1 2.8e-14 53.1 0.1 5.0 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP12043.1 - 2.9e-33 113.1 14.0 1.2e-08 34.9 0.1 7.9 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP12043.1 - 1.7e-31 105.0 10.6 0.0014 18.7 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat SPX PF03105.14 CEP12043.1 - 7.4e-28 98.0 17.3 9e-16 58.4 4.0 3.0 2 1 1 3 3 3 2 SPX domain GDPD PF03009.12 CEP12043.1 - 1.1e-22 80.7 0.0 5e-22 78.6 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SSP160 PF06933.6 CEP12043.1 - 0.6 8.0 15.5 0.87 7.4 10.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 CEP12043.1 - 2.9 5.6 6.3 4.4 5.0 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen M-factor PF03855.8 CEP12044.1 - 0.038 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 M-factor Ribosomal_L14 PF00238.14 CEP12045.1 - 8.4e-35 119.1 0.0 9.2e-35 119.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e AA_permease PF00324.16 CEP12046.1 - 3.2e-136 454.4 44.3 3.9e-136 454.1 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEP12046.1 - 3.6e-44 150.9 46.2 4.4e-44 150.7 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease TPR_11 PF13414.1 CEP12047.1 - 6.8e-52 173.0 37.3 2.4e-09 36.7 1.1 11.6 9 3 4 13 13 13 11 TPR repeat TPR_1 PF00515.23 CEP12047.1 - 1e-42 142.0 38.1 2.1e-05 23.8 0.5 16.0 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12047.1 - 5.7e-41 135.1 25.2 1.8e-05 24.2 0.8 15.8 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_16 PF13432.1 CEP12047.1 - 4.7e-40 135.4 7.0 3e-07 30.9 0.0 9.7 6 2 5 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.1 CEP12047.1 - 3e-39 132.8 31.6 2.7e-08 33.6 0.2 11.4 8 4 4 12 12 12 10 Tetratricopeptide repeat TPR_14 PF13428.1 CEP12047.1 - 2.2e-35 117.8 8.5 0.00012 22.3 0.0 14.2 9 4 6 15 15 13 7 Tetratricopeptide repeat TPR_19 PF14559.1 CEP12047.1 - 3.5e-33 113.7 23.8 3.1e-08 33.8 0.1 10.5 6 4 4 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.1 CEP12047.1 - 7.1e-29 97.2 17.1 0.00055 19.5 0.0 12.9 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_8 PF13181.1 CEP12047.1 - 9e-25 84.5 35.8 0.0024 17.5 0.0 14.8 17 1 0 17 17 17 7 Tetratricopeptide repeat TPR_6 PF13174.1 CEP12047.1 - 9.3e-23 79.0 37.9 7.9e-05 22.8 0.1 14.3 15 1 1 16 16 14 5 Tetratricopeptide repeat TPR_17 PF13431.1 CEP12047.1 - 6.9e-19 66.4 26.0 0.00042 20.2 0.1 13.2 16 0 0 16 16 13 4 Tetratricopeptide repeat Apc3 PF12895.2 CEP12047.1 - 9e-15 54.5 36.7 0.00051 20.1 1.3 8.0 6 3 1 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CEP12047.1 - 7.7e-09 35.2 4.3 6 6.7 0.0 8.2 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 CEP12047.1 - 1.2e-07 31.1 27.5 0.00018 20.6 1.2 5.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 CEP12047.1 - 3.4e-07 29.9 17.2 0.33 10.9 0.3 9.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPPII_N PF12583.3 CEP12047.1 - 0.001 19.2 4.0 0.052 13.6 0.0 3.6 3 1 1 4 4 3 1 Tripeptidyl peptidase II N terminal Fis1_TPR_C PF14853.1 CEP12047.1 - 0.081 12.8 0.1 0.081 12.8 0.1 7.3 9 0 0 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 CEP12047.1 - 0.43 10.5 33.0 0.13 12.1 0.1 6.1 5 3 0 5 5 5 0 Tetratricopeptide repeat PC_rep PF01851.17 CEP12048.1 - 4.4e-48 158.8 16.0 6.8e-09 35.4 0.1 10.0 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CEP12048.1 - 1.8e-16 60.1 0.2 1.6e-09 37.9 0.0 4.8 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 CEP12048.1 - 4e-09 35.7 0.0 2.2 8.5 0.1 6.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 CEP12048.1 - 5.4e-07 29.9 1.8 0.12 12.9 0.0 4.7 3 1 2 5 5 5 2 HEAT-like repeat HEAT_PBS PF03130.11 CEP12048.1 - 0.065 13.7 1.2 1.3e+02 3.4 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 CEP12048.1 - 0.072 13.0 0.1 3.5 7.6 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 LsmAD PF06741.8 CEP12048.1 - 7.3 6.7 9.9 0.42 10.7 2.4 2.3 2 0 0 2 2 2 0 LsmAD domain Methyltransf_16 PF10294.4 CEP12050.1 - 2.9e-28 98.4 0.1 7.7e-27 93.8 0.1 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CEP12050.1 - 8.9e-06 25.5 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP12050.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Stk19 PF10494.4 CEP12052.1 - 3.5e-22 79.0 0.2 1.3e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Serine-threonine protein kinase 19 DDE_3 PF13358.1 CEP12053.1 - 8e-29 100.2 0.0 3.5e-28 98.1 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP12053.1 - 3.7e-05 23.8 0.0 8.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP12053.1 - 0.0079 15.8 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.21 CEP12053.1 - 0.012 15.7 0.0 0.37 10.9 0.0 2.8 3 0 0 3 3 3 0 Integrase core domain DUF496 PF04363.7 CEP12053.1 - 0.06 13.1 0.1 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF496) HTH_17 PF12728.2 CEP12053.1 - 0.076 13.2 0.1 0.52 10.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.1 CEP12053.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MerR_1 PF13411.1 CEP12053.1 - 0.2 11.4 1.5 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein MIF4G PF02854.14 CEP12054.1 - 1.2e-63 214.2 10.1 2e-33 115.5 0.2 4.1 4 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 CEP12054.1 - 1.9e-42 144.9 18.1 1.9e-42 144.9 12.5 2.7 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Lysine_decarbox PF03641.9 CEP12054.1 - 2.5e-38 130.9 0.0 7.3e-38 129.3 0.0 1.9 1 0 0 1 1 1 1 Possible lysine decarboxylase Ras PF00071.17 CEP12055.1 - 2.7e-56 189.4 0.3 3.5e-56 189.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP12055.1 - 1.2e-13 51.5 0.0 2.5e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP12055.1 - 6.3e-10 38.5 0.1 8.8e-10 38.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP12055.1 - 2e-06 27.3 0.1 3.2e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP12055.1 - 0.0034 16.5 0.1 0.0085 15.2 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Big_3_2 PF12245.3 CEP12055.1 - 0.0069 15.9 0.1 1.7 8.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 3) MMR_HSR1 PF01926.18 CEP12055.1 - 0.073 13.0 0.1 0.31 11.0 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2868 PF11067.3 CEP12055.1 - 0.1 11.7 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) zf-C2H2 PF00096.21 CEP12056.1 - 2.4e-07 30.6 14.7 0.00077 19.6 3.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP12056.1 - 0.00055 20.1 4.2 0.00055 20.1 2.9 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP12056.1 - 0.00064 19.8 11.9 0.0037 17.4 1.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 CEP12056.1 - 0.13 12.3 3.7 0.82 9.8 0.3 2.4 1 1 1 2 2 2 0 Rtr1/RPAP2 family RRM_1 PF00076.17 CEP12057.1 - 1.8e-07 30.6 0.0 5.5e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.12 CEP12057.1 - 1.3e-06 28.0 0.1 7e-06 25.7 0.0 2.3 3 0 0 3 3 3 1 La domain RRM_6 PF14259.1 CEP12057.1 - 6e-05 22.9 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.19 CEP12058.1 - 1.6e-44 152.2 0.0 1.9e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEP12058.1 - 0.00033 20.7 0.0 0.003 17.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CEP12058.1 - 0.0067 16.4 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain TraI_2 PF07514.6 CEP12058.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative helicase NAD_binding_8 PF13450.1 CEP12058.1 - 0.011 15.6 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CEP12058.1 - 0.022 13.6 0.0 0.53 9.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Mqo PF06039.10 CEP12058.1 - 0.069 11.3 0.0 0.12 10.5 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 CEP12058.1 - 0.13 12.0 0.3 0.48 10.1 0.2 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pkinase PF00069.20 CEP12059.1 - 4.7e-53 179.9 0.0 1.1e-27 96.9 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12059.1 - 1.5e-21 76.6 0.1 6.3e-14 51.6 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ish1 PF10281.4 CEP12059.1 - 0.13 12.3 0.1 0.54 10.3 0.1 2.1 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Ank_2 PF12796.2 CEP12060.1 - 2.6e-23 82.1 0.0 9.5e-14 51.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP12060.1 - 8.2e-18 64.4 0.0 9.5e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CEP12060.1 - 2.3e-16 58.6 0.6 6.4e-08 32.0 0.0 4.5 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CEP12060.1 - 1.3e-14 53.8 0.0 5.5e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP12060.1 - 4.9e-14 51.0 0.1 2.4e-06 27.2 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Tex_N PF09371.5 CEP12060.1 - 0.039 13.2 4.9 0.71 9.1 0.8 2.4 1 1 1 2 2 2 0 Tex-like protein N-terminal domain Reo_sigmaC PF04582.7 CEP12061.1 - 6.6e-05 22.2 21.3 0.0071 15.5 1.2 3.6 2 2 1 3 3 3 3 Reovirus sigma C capsid protein RicinB_lectin_2 PF14200.1 CEP12062.1 - 2.1e-13 50.5 3.8 1.1e-06 28.8 0.1 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CEP12062.1 - 4.7e-12 46.0 1.1 1.4e-05 25.1 0.2 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RVT_1 PF00078.22 CEP12065.1 - 1.4e-31 109.5 0.4 7.4e-16 58.1 0.0 2.8 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CEP12065.1 - 0.0014 18.6 0.1 0.004 17.1 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 CEP12065.1 - 0.0037 17.0 0.8 0.014 15.2 0.5 2.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2526 PF10735.4 CEP12065.1 - 0.1 12.6 0.0 28 4.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) zf-LYAR PF08790.6 CEP12065.1 - 0.13 12.0 1.4 16 5.2 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Arrestin_N PF00339.24 CEP12066.1 - 4.6e-09 36.2 0.1 2.2e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP12066.1 - 7.3e-05 22.8 0.5 0.00014 21.9 0.4 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain SNF2_N PF00176.18 CEP12067.1 - 1.1e-81 273.9 0.2 1.1e-81 273.9 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 CEP12067.1 - 7.9e-42 141.7 2.9 3.2e-41 139.7 2.0 2.2 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 CEP12067.1 - 1.9e-26 92.6 6.0 1.9e-26 92.6 4.1 3.1 4 0 0 4 4 1 1 HAND Helicase_C PF00271.26 CEP12067.1 - 3.5e-16 58.8 0.0 1.1e-15 57.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP12067.1 - 4e-09 36.5 0.0 4e-09 36.5 0.0 3.7 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEP12067.1 - 5.6e-05 22.7 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.1 CEP12067.1 - 0.00011 22.2 0.9 0.00011 22.2 0.6 4.7 3 1 1 4 4 2 1 DNA-binding domain DUF1086 PF06461.6 CEP12067.1 - 0.00072 19.3 0.0 0.0027 17.5 0.0 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Myb_DNA-binding PF00249.26 CEP12067.1 - 0.0011 19.0 0.0 0.5 10.4 0.0 3.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain AAA_14 PF13173.1 CEP12067.1 - 0.014 15.2 0.3 0.073 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CEP12067.1 - 0.052 13.7 0.3 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-H2C2_2 PF13465.1 CEP12068.1 - 1.3e-06 28.3 21.2 1.4e-06 28.2 0.5 4.9 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEP12068.1 - 2.3e-06 27.6 19.1 0.00023 21.2 4.2 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP12068.1 - 0.0031 17.7 16.2 0.0093 16.2 3.4 4.9 5 1 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.2 CEP12068.1 - 0.0069 16.5 7.8 0.012 15.7 1.2 3.4 2 1 1 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP12068.1 - 0.032 14.3 2.5 0.032 14.3 1.7 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CEP12068.1 - 0.18 11.6 10.0 4.1 7.2 1.2 2.7 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 CEP12068.1 - 1.2 8.8 12.7 1.4 8.6 1.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PQ-loop PF04193.9 CEP12069.1 - 1.2e-19 69.5 1.0 1.2e-19 69.5 0.7 2.4 2 0 0 2 2 2 1 PQ loop repeat SR-25 PF10500.4 CEP12069.1 - 1 8.7 8.7 1.5 8.2 6.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Kin17_mid PF10357.4 CEP12071.1 - 2.5e-44 149.9 0.4 2.5e-44 149.9 0.3 3.8 3 1 3 6 6 6 1 Domain of Kin17 curved DNA-binding protein OB_NTP_bind PF07717.11 CEP12071.1 - 2.5e-30 104.6 0.0 1e-29 102.6 0.0 2.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CEP12071.1 - 3.5e-21 75.1 0.1 3.5e-21 75.1 0.1 4.1 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEP12071.1 - 4e-14 52.2 0.0 1.1e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CEP12071.1 - 4.1e-06 26.9 4.4 0.0017 18.5 0.0 4.5 3 1 0 3 3 3 1 AAA domain DEAD PF00270.24 CEP12071.1 - 1e-05 25.1 0.0 4e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CEP12071.1 - 0.0025 16.7 0.0 0.0057 15.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein zf-C2H2_jaz PF12171.3 CEP12071.1 - 0.02 15.0 6.1 0.048 13.8 4.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP12071.1 - 0.1 12.8 5.2 0.21 11.8 3.6 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Mito_carr PF00153.22 CEP12072.1 - 2.9e-74 244.8 3.0 1.2e-26 92.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CEP12072.1 - 1.7e-17 63.2 8.7 0.0001 22.3 0.5 4.9 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.27 CEP12072.1 - 5.8e-16 56.5 11.1 1.3e-05 24.1 0.0 6.6 7 0 0 7 7 7 3 EF hand EF-hand_6 PF13405.1 CEP12072.1 - 8.7e-15 53.2 11.5 0.00022 20.8 0.0 7.0 7 0 0 7 7 7 3 EF-hand domain EF-hand_8 PF13833.1 CEP12072.1 - 2.4e-12 46.2 5.2 0.0061 16.1 0.1 4.8 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CEP12072.1 - 3.9e-06 25.9 5.5 0.012 14.9 0.1 4.5 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.1 CEP12072.1 - 0.18 11.7 0.8 12 5.9 0.0 3.9 5 0 0 5 5 5 0 EF-hand domain EF-hand_4 PF12763.2 CEP12072.1 - 0.66 9.7 3.0 1.3 8.8 0.0 2.8 3 1 2 5 5 5 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 CEP12073.1 - 7.7e-71 238.2 0.0 2.2e-70 236.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12073.1 - 6.1e-34 117.2 0.0 1.4e-31 109.5 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP12073.1 - 2.5e-06 26.6 1.2 0.055 12.4 0.0 2.9 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CEP12073.1 - 9.2e-05 21.8 0.8 0.00019 20.8 0.6 1.5 1 0 0 1 1 1 1 RIO1 family Tim17 PF02466.14 CEP12074.1 - 5.4e-28 97.6 0.4 1.1e-27 96.5 0.2 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Myb_DNA-bind_4 PF13837.1 CEP12076.1 - 0.01 15.9 0.3 0.017 15.2 0.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3439 PF11921.3 CEP12076.1 - 2.5 7.8 11.3 4.4 7.0 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SE PF08491.5 CEP12077.1 - 2.2e-108 361.2 0.0 3.5e-108 360.6 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase SAPS PF04499.10 CEP12077.1 - 1.7e-100 336.9 12.5 5.6e-55 186.8 7.2 3.3 1 1 2 3 3 3 2 SIT4 phosphatase-associated protein FAD_binding_3 PF01494.14 CEP12077.1 - 1e-13 51.0 0.0 1.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEP12077.1 - 9.4e-08 31.3 0.0 0.003 16.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP12077.1 - 0.00081 18.3 0.6 0.54 9.0 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 CEP12077.1 - 0.0017 17.3 0.8 0.01 14.7 0.6 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 CEP12077.1 - 0.0024 17.0 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CEP12077.1 - 0.0055 16.6 0.2 0.012 15.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CEP12077.1 - 0.041 12.9 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDI PF00996.13 CEP12077.1 - 0.05 11.9 0.1 0.089 11.0 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor YIF1 PF03878.10 CEP12077.1 - 0.052 12.7 0.1 0.052 12.7 0.1 1.6 2 0 0 2 2 2 0 YIF1 Pyr_redox_2 PF07992.9 CEP12077.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP12077.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 CEP12077.1 - 0.21 10.6 0.1 15 4.6 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Cupin_4 PF08007.7 CEP12078.1 - 0.1 11.8 0.2 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Kinetocho_Slk19 PF12709.2 CEP12078.1 - 0.21 11.7 5.5 0.23 11.5 2.5 2.0 2 0 0 2 2 2 0 Central kinetochore-associated Aa_trans PF01490.13 CEP12079.1 - 6.1e-62 209.4 23.4 7.3e-62 209.1 16.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein bZIP_1 PF00170.16 CEP12080.1 - 4.5e-11 42.5 8.6 4.5e-11 42.5 6.0 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP12080.1 - 4.1e-08 32.9 7.8 1.1e-07 31.5 5.4 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_HRA PF11786.3 CEP12080.1 - 5e-07 29.8 1.0 5e-07 29.8 0.7 2.5 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_OSA PF11785.3 CEP12080.1 - 1.4e-05 25.5 3.8 1.4e-05 25.5 2.6 5.2 3 3 2 5 5 5 1 Aft1 osmotic stress response (OSM) domain HALZ PF02183.13 CEP12080.1 - 0.0076 15.9 2.8 0.014 15.0 1.9 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_Maf PF03131.12 CEP12080.1 - 0.021 15.0 4.9 0.021 15.0 3.4 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Mg_trans_NIPA PF05653.9 CEP12082.1 - 8.1e-19 67.6 20.4 2.5e-12 46.3 6.0 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF843 PF05814.6 CEP12082.1 - 0.0014 18.3 2.4 0.0014 18.3 1.6 2.7 3 0 0 3 3 3 1 Baculovirus protein of unknown function (DUF843) NST1 PF13945.1 CEP12083.1 - 5.2e-49 166.8 11.9 5.2e-49 166.8 8.2 4.0 3 1 1 4 4 4 1 Salt tolerance down-regulator DUF4105 PF13387.1 CEP12083.1 - 5.1 6.2 8.8 1.7 7.8 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) CUE PF02845.11 CEP12084.1 - 6.7e-10 38.2 0.0 1.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 CUE domain Vma12 PF11712.3 CEP12084.1 - 0.17 11.5 2.0 0.38 10.4 1.4 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Miro PF08477.8 CEP12085.1 - 9.8e-39 132.5 0.0 2.1e-21 76.6 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 CEP12085.1 - 8.1e-34 115.2 0.0 1.8e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 CEP12085.1 - 2e-30 103.9 2.0 3.6e-30 103.0 1.4 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 CEP12085.1 - 2.4e-30 105.0 0.0 1.9e-20 72.9 0.0 2.3 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 CEP12085.1 - 8.5e-11 41.8 0.0 0.00038 20.4 0.0 3.2 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 CEP12085.1 - 3.2e-08 33.7 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CEP12085.1 - 5.6e-07 29.7 0.1 0.023 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.1 CEP12085.1 - 5.8e-07 29.3 0.0 0.038 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CEP12085.1 - 1.7e-06 28.2 0.0 0.025 14.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CEP12085.1 - 1.8e-06 28.0 0.0 0.014 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CEP12085.1 - 2.4e-06 27.4 0.1 0.11 12.2 0.0 2.7 2 1 1 3 3 3 2 Dynamin family AAA_29 PF13555.1 CEP12085.1 - 4.2e-06 26.1 0.0 0.016 14.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Arf PF00025.16 CEP12085.1 - 4.9e-06 25.9 0.0 0.0016 17.6 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.22 CEP12085.1 - 5.9e-06 26.6 0.0 0.043 14.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter NACHT PF05729.7 CEP12085.1 - 6.2e-06 25.9 0.1 0.13 11.8 0.0 2.9 2 1 1 3 3 3 2 NACHT domain MobB PF03205.9 CEP12085.1 - 1.5e-05 24.7 0.1 0.026 14.2 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_7 PF13499.1 CEP12085.1 - 1.6e-05 24.9 1.2 0.11 12.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CEP12085.1 - 2.3e-05 23.3 5.0 0.013 14.7 0.3 2.6 2 0 0 2 2 2 2 EF hand AAA_18 PF13238.1 CEP12085.1 - 2.8e-05 24.4 0.0 0.31 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Septin PF00735.13 CEP12085.1 - 5.2e-05 22.3 0.0 0.0092 15.0 0.0 2.4 2 0 0 2 2 2 1 Septin EF-hand_6 PF13405.1 CEP12085.1 - 9.6e-05 21.9 3.2 0.29 11.1 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_5 PF07728.9 CEP12085.1 - 0.00011 21.9 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CEP12085.1 - 0.00011 21.9 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 CEP12085.1 - 0.00014 21.3 0.0 0.34 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_33 PF13671.1 CEP12085.1 - 0.00015 21.6 0.0 0.63 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain SRPRB PF09439.5 CEP12085.1 - 0.0002 20.6 0.0 0.085 12.0 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 CEP12085.1 - 0.00022 21.3 0.0 0.83 9.8 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_17 PF13207.1 CEP12085.1 - 0.00022 21.9 0.0 0.28 11.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 CEP12085.1 - 0.00031 20.2 0.3 0.27 10.5 0.0 2.9 2 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 CEP12085.1 - 0.00032 20.2 0.0 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 CEP12085.1 - 0.00078 18.6 0.0 0.032 13.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 CEP12085.1 - 0.00079 18.9 0.1 0.26 10.6 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain EF-hand_10 PF14788.1 CEP12085.1 - 0.0016 18.0 3.3 0.019 14.6 0.3 2.5 2 0 0 2 2 2 1 EF hand ATP_bind_1 PF03029.12 CEP12085.1 - 0.0017 17.9 0.2 2.3 7.7 0.0 3.4 4 0 0 4 4 3 1 Conserved hypothetical ATP binding protein DUF815 PF05673.8 CEP12085.1 - 0.0023 16.9 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 CEP12085.1 - 0.0034 16.8 0.9 3 7.2 0.0 3.5 3 1 0 4 4 4 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 CEP12085.1 - 0.0051 16.3 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.1 CEP12085.1 - 0.0053 16.6 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CEP12085.1 - 0.0071 15.2 0.0 2.5 6.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 CEP12085.1 - 0.011 14.8 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MCM PF00493.18 CEP12085.1 - 0.015 14.1 0.0 0.18 10.5 0.0 2.3 2 0 0 2 2 2 0 MCM2/3/5 family PduV-EutP PF10662.4 CEP12085.1 - 0.016 14.6 0.0 6.8 6.1 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF-hand_5 PF13202.1 CEP12085.1 - 0.017 14.4 7.7 0.49 9.8 0.9 2.6 2 0 0 2 2 2 0 EF hand UPF0079 PF02367.12 CEP12085.1 - 0.021 14.4 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 EF-hand_8 PF13833.1 CEP12085.1 - 0.023 14.3 3.0 2.1 8.0 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair AAA_32 PF13654.1 CEP12085.1 - 0.029 13.0 0.0 0.43 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CEP12085.1 - 0.03 13.8 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 CEP12085.1 - 0.031 12.9 0.1 3.6 6.1 0.0 2.6 3 0 0 3 3 2 0 G-protein alpha subunit Sigma54_activat PF00158.21 CEP12085.1 - 0.032 13.7 0.0 5.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.1 CEP12085.1 - 0.032 13.9 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 CEP12085.1 - 0.036 13.7 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 CEP12085.1 - 0.041 13.0 0.1 9.8 5.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CEP12085.1 - 0.044 13.1 0.0 7.7 5.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 CEP12085.1 - 0.047 12.6 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 CEP12085.1 - 0.047 14.0 0.4 7.9 6.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.7 CEP12085.1 - 0.077 12.2 0.0 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein T2SE PF00437.15 CEP12085.1 - 0.11 11.4 0.1 8.5 5.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DNA_ligase_A_M PF01068.16 CEP12086.1 - 6.4e-62 208.5 0.3 6.4e-62 208.5 0.2 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CEP12086.1 - 1.8e-53 181.0 0.1 4.3e-53 179.7 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CEP12086.1 - 1.4e-26 92.6 0.0 1.2e-25 89.6 0.0 2.6 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CEP12086.1 - 0.011 15.4 0.4 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.14 CEP12086.1 - 0.028 14.1 0.3 0.18 11.4 0.2 2.3 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain DUF4551 PF15087.1 CEP12086.1 - 1.2 7.4 10.9 1.8 6.7 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) WD40 PF00400.27 CEP12087.1 - 9.6e-25 85.5 9.4 1.1e-06 28.3 0.6 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Caudo_TAP PF02413.12 CEP12087.1 - 0.064 13.4 0.1 0.15 12.2 0.0 1.5 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein UCR_hinge PF02320.11 CEP12089.1 - 1.8e-18 66.2 4.4 1.8e-18 66.2 3.0 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein FEZ PF07763.8 CEP12089.1 - 0.011 15.4 1.2 0.012 15.3 0.8 1.1 1 0 0 1 1 1 0 FEZ-like protein DUF2052 PF09747.4 CEP12089.1 - 0.097 12.5 0.8 0.11 12.4 0.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Macin PF14865.1 CEP12089.1 - 2.5 8.2 5.6 1.4 9.0 2.4 1.7 1 1 1 2 2 2 0 Macin PqqD PF05402.7 CEP12089.1 - 3.3 7.8 5.2 8.6 6.4 2.8 2.0 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) SIR2_2 PF13289.1 CEP12090.1 - 0.084 12.7 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 SIR2-like domain FYRN PF05964.9 CEP12091.1 - 3e-20 71.4 0.2 7.4e-20 70.1 0.1 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 CEP12091.1 - 8.8e-15 54.2 0.0 2.1e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus DUF2828 PF11443.3 CEP12093.1 - 4.1e-128 427.9 2.5 5.2e-127 424.2 1.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) Rsm22 PF09243.5 CEP12093.1 - 0.03 13.3 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 zinc_ribbon_6 PF14599.1 CEP12094.1 - 2.3e-25 88.1 0.6 2.3e-25 88.1 0.4 4.6 5 1 0 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 CEP12094.1 - 3.1e-16 59.2 23.0 3.1e-16 59.2 16.0 4.8 3 1 1 4 4 4 2 CHY zinc finger zf-RING_2 PF13639.1 CEP12094.1 - 6.9e-09 35.3 10.6 6.9e-09 35.3 7.3 5.7 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP12094.1 - 3.2e-06 27.0 9.7 3.2e-06 27.0 6.7 6.0 2 2 4 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEP12094.1 - 0.0016 18.5 14.3 0.0016 18.5 9.9 4.3 2 1 1 3 3 3 1 RING-H2 zinc finger Tcf25 PF04910.9 CEP12095.1 - 8.5e-86 288.1 4.2 1.4e-85 287.3 2.9 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 GRASP55_65 PF04495.9 CEP12096.1 - 3e-66 221.6 0.0 1.9e-48 163.9 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CEP12096.1 - 3.2e-05 23.7 0.0 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 CEP12096.1 - 0.0044 17.1 0.0 0.42 10.8 0.0 2.3 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 CEP12096.1 - 0.097 12.4 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain HSP70 PF00012.15 CEP12097.1 - 0.12 10.2 0.0 0.27 9.0 0.0 1.5 2 0 0 2 2 2 0 Hsp70 protein UQ_con PF00179.21 CEP12098.1 - 3.5e-37 126.9 0.1 4.5e-37 126.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RVT_1 PF00078.22 CEP12100.1 - 4.7e-29 101.2 0.0 7.1e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L20 PF00453.13 CEP12100.1 - 0.043 13.7 0.4 0.089 12.7 0.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L20 PMR5N PF14416.1 CEP12100.1 - 0.12 12.4 1.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 PMR5 N terminal Domain Exo_endo_phos_2 PF14529.1 CEP12101.1 - 7.4e-15 54.6 0.0 2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP12101.1 - 2.4e-07 30.9 0.2 6.4e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Angiomotin_C PF12240.3 CEP12101.1 - 0.0088 15.5 1.6 0.015 14.7 1.1 1.3 1 0 0 1 1 1 1 Angiomotin C terminal TSC22 PF01166.13 CEP12101.1 - 0.063 13.2 3.3 0.08 12.9 1.3 2.0 1 1 1 2 2 2 0 TSC-22/dip/bun family Spc7 PF08317.6 CEP12101.1 - 0.094 11.3 3.4 0.14 10.8 2.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.16 CEP12101.1 - 0.31 11.0 2.1 0.65 10.0 1.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor CoA_transf_3 PF02515.12 CEP12102.1 - 2.1e-67 226.0 0.0 2.8e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III CS PF04969.11 CEP12103.1 - 3e-11 43.7 0.2 6.4e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 CS domain RINT1_TIP1 PF04437.8 CEP12104.1 - 6e-96 321.9 11.3 6e-96 321.9 7.8 2.2 2 1 0 2 2 2 2 RINT-1 / TIP-1 family LXG PF04740.7 CEP12104.1 - 0.086 12.6 11.6 0.15 11.8 3.8 3.3 2 1 0 2 2 2 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.7 CEP12104.1 - 4.6 7.0 15.9 3.2 7.5 0.1 3.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DSPc PF00782.15 CEP12105.1 - 2.5e-29 101.5 0.1 3.5e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP12105.1 - 0.025 13.9 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF1473 PF07341.6 CEP12105.1 - 0.031 13.8 0.2 0.11 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1473) ANTAR PF03861.9 CEP12105.1 - 0.16 11.5 0.1 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 ANTAR domain MFS_1 PF07690.11 CEP12106.1 - 2.5e-43 148.1 47.1 5.1e-38 130.6 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 CEP12106.1 - 0.066 13.6 0.8 0.22 11.9 0.6 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TPR_11 PF13414.1 CEP12107.1 - 4.9e-14 51.7 0.4 3.1e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CEP12107.1 - 1.1e-09 37.5 2.1 0.0028 17.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12107.1 - 6.8e-09 34.9 1.2 0.0028 17.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP12107.1 - 8.2e-07 29.5 0.6 0.0052 17.4 0.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat F-box-like PF12937.2 CEP12107.1 - 3.1e-05 23.5 0.0 6.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like TPR_7 PF13176.1 CEP12107.1 - 0.00015 21.3 0.1 0.066 13.0 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box PF00646.28 CEP12107.1 - 0.00018 21.0 0.0 0.00048 19.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain TPR_14 PF13428.1 CEP12107.1 - 0.00025 21.4 0.5 2.7 8.8 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP12107.1 - 0.00037 20.3 2.2 0.013 15.4 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP12107.1 - 0.011 15.8 1.0 2.6 8.2 0.1 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CEP12107.1 - 0.017 15.4 0.9 1.5 9.1 0.6 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 CEP12107.1 - 0.026 14.3 0.1 0.054 13.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP12107.1 - 0.028 14.1 1.6 18 5.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP12107.1 - 0.029 14.7 2.5 11 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.28 CEP12107.1 - 0.075 13.0 4.8 22 5.6 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat TPR_17 PF13431.1 CEP12107.1 - 0.095 12.9 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.1 CEP12107.1 - 0.54 10.4 8.1 15 5.9 0.0 5.6 7 0 0 7 7 5 0 Leucine Rich repeat LRR_7 PF13504.1 CEP12107.1 - 2.3 8.8 10.6 13 6.5 0.0 5.5 6 1 0 6 6 4 0 Leucine rich repeat Arrestin_N PF00339.24 CEP12108.1 - 2.6e-13 50.0 0.0 6.7e-12 45.4 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP12108.1 - 1.8e-06 28.0 0.5 7.8e-06 26.0 0.5 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 CEP12108.1 - 0.015 14.8 0.0 0.21 11.0 0.0 2.5 2 1 1 3 3 3 0 Arrestin_N terminal like DUF1752 PF08550.5 CEP12109.1 - 2.8e-09 36.3 1.7 7.9e-09 34.9 1.1 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DUF1814 PF08843.6 CEP12109.1 - 0.062 13.0 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) WES_acyltransf PF03007.11 CEP12110.1 - 3.5e-19 69.3 0.1 2.5e-16 60.0 0.0 2.0 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.15 CEP12110.1 - 0.0027 16.6 0.0 0.02 13.7 0.1 2.0 2 0 0 2 2 2 1 Condensation domain DUF1298 PF06974.8 CEP12110.1 - 0.0059 16.4 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) DUF3366 PF11846.3 CEP12110.1 - 0.091 12.6 0.1 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) zf-C2H2 PF00096.21 CEP12111.1 - 3e-07 30.3 12.0 0.00049 20.2 1.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CEP12111.1 - 0.00016 21.7 9.6 0.0048 17.0 1.3 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP12111.1 - 0.0032 17.6 0.6 0.0032 17.6 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CEP12111.1 - 0.03 14.6 3.5 0.03 14.6 2.4 3.6 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP12111.1 - 0.03 14.6 1.2 0.03 14.6 0.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Cytochrome_C554 PF13435.1 CEP12111.1 - 0.037 14.0 6.2 0.069 13.2 4.3 1.4 1 0 0 1 1 1 0 Cytochrome c554 and c-prime C1_4 PF07975.7 CEP12111.1 - 0.84 9.6 6.2 8.9 6.4 0.1 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain Ndc80_HEC PF03801.8 CEP12112.1 - 3.5e-30 104.5 0.2 9.4e-30 103.1 0.2 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family DUF2353 PF09789.4 CEP12112.1 - 0.0085 15.3 30.9 0.02 14.1 9.1 2.5 2 0 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) AP_endonuc_2 PF01261.19 CEP12112.1 - 0.041 13.1 0.1 7.1 5.8 0.0 2.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Reo_sigmaC PF04582.7 CEP12112.1 - 0.067 12.3 5.7 0.067 12.3 0.3 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 CEP12112.1 - 1.6 8.1 47.7 0.031 13.7 20.6 2.7 2 1 1 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 CEP12112.1 - 4.1 7.1 43.7 0.95 9.2 11.0 4.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ACPS PF01648.15 CEP12113.1 - 5.9e-13 48.6 0.0 8.8e-12 44.8 0.0 2.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DUF2407 PF10302.4 CEP12113.1 - 0.061 13.5 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEP12113.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Amino_oxidase PF01593.19 CEP12116.1 - 2e-58 198.5 0.0 1.5e-45 156.0 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEP12116.1 - 8.3e-08 32.1 0.2 2e-07 30.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CEP12116.1 - 1.5e-05 25.1 0.3 0.00011 22.3 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP12116.1 - 3.8e-05 22.7 0.2 0.0034 16.3 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CEP12116.1 - 0.0036 16.4 0.1 0.007 15.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CEP12116.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 CEP12116.1 - 0.022 14.6 0.1 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 CEP12116.1 - 0.031 14.3 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 CEP12116.1 - 0.037 14.0 0.4 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Malic_M PF03949.10 CEP12116.1 - 0.045 13.2 0.4 0.2 11.1 0.1 1.9 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 CEP12116.1 - 0.046 14.1 0.6 0.48 10.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CEP12116.1 - 0.055 12.2 0.3 0.11 11.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 CEP12116.1 - 0.066 12.2 0.1 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CEP12116.1 - 0.16 10.4 1.3 0.21 9.9 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein STE PF02200.11 CEP12117.1 - 9.6e-53 177.0 0.0 1.9e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2_4 PF13894.1 CEP12117.1 - 9.4e-07 28.7 9.2 0.0024 18.0 1.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP12117.1 - 5.8e-05 23.1 8.4 0.002 18.3 1.7 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type IBR PF01485.16 CEP12117.1 - 0.09 12.6 0.4 0.24 11.3 0.3 1.6 1 0 0 1 1 1 0 IBR domain DUF663 PF04950.7 CEP12117.1 - 2 7.3 8.4 0.025 13.5 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF663) Pkinase PF00069.20 CEP12118.1 - 1.2e-72 244.2 0.4 1.2e-72 244.2 0.3 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12118.1 - 1.4e-52 178.3 0.3 3.3e-52 177.1 0.2 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CEP12118.1 - 2.2e-19 69.6 0.5 2e-18 66.5 0.0 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 CEP12118.1 - 7.7e-11 42.1 0.6 2.1e-10 40.7 0.4 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CEP12118.1 - 5e-06 25.6 0.1 0.00011 21.2 0.0 2.4 1 1 1 2 2 2 1 Kinase-like PH_11 PF15413.1 CEP12118.1 - 0.00011 22.3 3.4 0.0025 18.0 0.3 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain APH PF01636.18 CEP12118.1 - 0.0031 17.2 0.1 0.91 9.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family PH_9 PF15410.1 CEP12118.1 - 0.013 15.6 1.5 0.98 9.5 0.2 3.4 2 1 0 2 2 2 0 Pleckstrin homology domain FlxA PF14282.1 CEP12119.1 - 0.011 15.6 2.9 0.013 15.3 2.0 1.2 1 0 0 1 1 1 0 FlxA-like protein SPACA7 PF15307.1 CEP12119.1 - 0.033 14.3 0.1 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 LysM PF01476.15 CEP12119.1 - 0.095 12.6 0.3 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 LysM domain YbaB_DNA_bd PF02575.11 CEP12119.1 - 0.44 10.4 2.8 0.59 10.0 1.9 1.2 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Exo_endo_phos PF03372.18 CEP12120.1 - 7.9e-05 22.7 1.1 0.0001 22.3 0.7 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP12120.1 - 0.034 13.7 0.9 5.8 6.5 0.1 2.8 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase LRR_4 PF12799.2 CEP12121.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) PP2C PF00481.16 CEP12123.1 - 6.5e-75 251.8 0.0 8.8e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CEP12123.1 - 0.00029 20.5 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) dCMP_cyt_deam_1 PF00383.17 CEP12124.1 - 2.8e-25 87.9 0.3 4.1e-25 87.3 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.1 CEP12124.1 - 0.0013 18.4 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.1 CEP12124.1 - 0.0083 15.9 0.5 0.045 13.6 0.3 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase Ribonuc_red_lgC PF02867.10 CEP12125.1 - 1.8e-209 696.7 0.0 2.6e-209 696.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CEP12125.1 - 4.1e-23 80.9 0.0 1.1e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CEP12125.1 - 2.7e-13 50.1 0.5 5.4e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 CEP12125.1 - 0.034 12.2 0.0 0.054 11.5 0.0 1.3 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase TPR_12 PF13424.1 CEP12126.1 - 1.1e-08 34.9 3.0 0.002 18.0 0.2 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP12126.1 - 2.4e-07 31.2 0.4 0.0033 18.0 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEP12126.1 - 1.5e-06 27.7 5.5 0.00022 20.8 0.3 3.9 3 1 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 CEP12126.1 - 1.2e-05 24.7 10.4 1.1 9.3 0.3 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP12126.1 - 7.4e-05 22.6 0.2 0.16 12.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP12126.1 - 8.8e-05 22.7 1.4 0.07 13.4 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP12126.1 - 0.0016 17.9 4.5 13 5.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP12126.1 - 0.0029 18.1 1.7 4 8.3 0.0 4.2 3 2 2 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CEP12126.1 - 0.014 15.5 5.6 0.28 11.3 0.9 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CEP12126.1 - 0.3 10.9 2.5 5.5 7.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP12126.1 - 0.33 10.8 9.4 3.5 7.6 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-bind_6 PF13921.1 CEP12127.1 - 0.00079 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SARG PF15385.1 CEP12127.1 - 0.0093 15.3 1.5 0.011 15.1 1.0 1.2 1 0 0 1 1 1 1 Specifically androgen-regulated gene protein DUF3844 PF12955.2 CEP12128.1 - 1.5e-11 44.3 14.2 4.5e-11 42.7 9.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 CEP12128.1 - 0.01 15.9 16.8 0.017 15.2 11.6 1.3 1 0 0 1 1 1 0 EGF-like domain Phage_connect_1 PF05135.8 CEP12128.1 - 0.013 15.6 0.8 0.036 14.2 0.5 1.8 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein EGF_3 PF12947.2 CEP12128.1 - 0.56 10.2 16.6 0.96 9.4 11.5 1.4 1 0 0 1 1 1 0 EGF domain DUF2972 PF11186.3 CEP12128.1 - 0.63 9.8 8.4 0.71 9.7 5.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) EGF PF00008.22 CEP12128.1 - 1.2 9.1 10.5 1.8 8.5 7.2 1.3 1 0 0 1 1 1 0 EGF-like domain Elf1 PF05129.8 CEP12129.1 - 0.012 15.2 0.1 0.043 13.5 0.1 2.0 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like COG2 PF06148.6 CEP12129.1 - 2.2 8.1 10.2 2 8.3 1.0 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 CEP12129.1 - 9.9 5.0 31.4 0.32 9.8 4.0 2.7 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 zf-CCHC PF00098.18 CEP12130.1 - 0.00023 20.9 12.8 0.003 17.3 0.2 3.9 4 0 0 4 4 4 2 Zinc knuckle Prok-RING_1 PF14446.1 CEP12130.1 - 0.0034 17.0 12.0 0.028 14.1 0.4 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.1 CEP12130.1 - 0.0041 16.2 7.2 0.38 10.0 0.2 3.5 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CEP12130.1 - 0.0066 15.8 5.2 0.6 9.6 0.2 3.4 3 0 0 3 3 3 1 zinc-ribbon domain DUF164 PF02591.10 CEP12130.1 - 0.014 15.2 6.2 0.62 9.9 0.4 3.7 4 0 0 4 4 3 0 Putative zinc ribbon domain DUF4193 PF13834.1 CEP12130.1 - 0.027 14.6 1.3 0.027 14.6 0.9 1.7 2 1 0 2 2 1 0 Domain of unknown function (DUF4193) AA_kinase PF00696.23 CEP12130.1 - 0.049 13.1 0.1 4.8 6.6 0.0 2.0 1 1 1 2 2 2 0 Amino acid kinase family Myc_target_1 PF15179.1 CEP12130.1 - 0.068 12.7 3.9 4.3 6.8 0.0 2.0 1 1 1 2 2 2 0 Myc target protein 1 HypA PF01155.14 CEP12130.1 - 0.075 12.7 13.5 0.76 9.4 1.0 3.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family YokU PF14122.1 CEP12130.1 - 0.13 11.9 0.2 0.13 11.9 0.2 2.6 2 1 2 4 4 4 0 YokU-like protein Ribosomal_L32p PF01783.18 CEP12130.1 - 0.14 12.3 12.1 2.1 8.5 3.9 3.0 2 1 1 3 3 3 0 Ribosomal L32p protein family OrfB_Zn_ribbon PF07282.6 CEP12130.1 - 0.2 11.3 12.5 1.5 8.5 0.6 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-C4_Topoisom PF01396.14 CEP12130.1 - 0.3 10.6 5.5 0.91 9.0 0.2 3.2 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Nudix_N_2 PF14803.1 CEP12130.1 - 0.31 10.7 9.9 0.64 9.7 0.2 3.5 3 0 0 3 3 3 0 Nudix N-terminal zf-H2C2_2 PF13465.1 CEP12130.1 - 0.39 11.1 9.7 18 5.8 1.1 3.9 3 2 0 3 3 3 0 Zinc-finger double domain ZZ PF00569.12 CEP12130.1 - 0.39 10.2 4.6 15 5.1 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, ZZ type zinc_ribbon_4 PF13717.1 CEP12130.1 - 0.41 10.3 4.3 22 4.8 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Sgf11 PF08209.6 CEP12130.1 - 0.5 9.7 9.0 4.6 6.6 0.1 3.8 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_5 PF13719.1 CEP12130.1 - 0.57 9.8 4.1 20 4.8 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 CEP12130.1 - 0.64 9.8 6.0 5.8 6.7 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.7 CEP12130.1 - 0.85 8.9 6.5 25 4.2 0.1 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding YhfH PF14149.1 CEP12130.1 - 2.7 7.8 6.4 52 3.7 0.0 3.4 3 0 0 3 3 3 0 YhfH-like protein DUF1610 PF07754.6 CEP12130.1 - 4 7.6 10.6 3.9 7.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) DZR PF12773.2 CEP12130.1 - 6 6.7 15.9 1.8 8.4 2.1 3.3 2 1 1 3 3 3 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 CEP12130.1 - 6.1 6.7 15.9 0.65 9.8 0.9 3.4 2 2 0 2 2 2 0 Transposase zinc-ribbon domain CpXC PF14353.1 CEP12130.1 - 8.1 6.4 7.2 5.3 7.0 0.2 3.0 1 1 2 3 3 3 0 CpXC protein zinc-ribbons_6 PF07191.7 CEP12130.1 - 9.1 6.1 12.0 2.7 7.8 1.4 3.1 3 0 0 3 3 3 0 zinc-ribbons PDEase_II PF02112.10 CEP12131.1 - 0.017 14.1 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Helitron_like_N PF14214.1 CEP12132.1 - 4.4e-18 65.6 0.0 1.1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DEC-1_N PF04625.8 CEP12133.1 - 9.3 4.8 13.3 20 3.7 9.2 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RVT_1 PF00078.22 CEP12136.1 - 0.00016 21.0 0.1 0.0032 16.8 0.1 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP12137.1 - 3e-07 30.0 0.6 9.1e-07 28.5 0.1 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP12137.1 - 9.4e-06 25.7 0.5 1.8e-05 24.8 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4363 PF14276.1 CEP12137.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) GCR1_C PF12550.3 CEP12137.1 - 0.12 12.2 3.2 4.3 7.2 0.1 2.4 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes Osmo_CC PF08946.5 CEP12137.1 - 8.2 6.5 6.0 13 5.9 0.8 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil KcnmB2_inactiv PF09303.5 CEP12138.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Spectrin PF00435.16 CEP12139.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Spectrin repeat TMF_DNA_bd PF12329.3 CEP12139.1 - 0.085 12.6 2.1 0.17 11.7 1.4 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA PF00004.24 CEP12140.1 - 8e-13 48.7 0.0 2.3e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP12140.1 - 5.4e-09 36.2 0.4 3.3e-08 33.7 0.0 2.4 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.10 CEP12140.1 - 2.1e-07 30.0 3.2 1.7e-05 23.7 0.0 2.9 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CEP12140.1 - 4.7e-06 26.5 0.0 1.4e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEP12140.1 - 1.9e-05 23.8 0.0 3.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CEP12140.1 - 1.9e-05 24.3 0.0 6.4e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CEP12140.1 - 0.00036 20.4 0.0 0.0014 18.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP12140.1 - 0.00039 21.2 0.0 0.00039 21.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 CEP12140.1 - 0.0014 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 CEP12140.1 - 0.0017 17.4 0.0 0.0043 16.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DNA_topoisoIV PF00521.15 CEP12140.1 - 0.0018 17.2 6.2 0.0037 16.1 0.7 2.4 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A NB-ARC PF00931.17 CEP12140.1 - 0.0026 16.6 0.6 0.0055 15.6 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 CEP12140.1 - 0.0036 17.6 0.0 0.0036 17.6 0.0 3.4 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 CEP12140.1 - 0.0059 16.9 3.8 0.065 13.5 0.2 3.2 2 1 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.12 CEP12140.1 - 0.012 15.0 0.1 0.084 12.2 0.1 2.2 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 CEP12140.1 - 0.012 15.6 0.1 0.11 12.5 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 CEP12140.1 - 0.013 14.3 0.3 0.038 12.8 0.2 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 CEP12140.1 - 0.017 14.7 0.1 0.047 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP12140.1 - 0.019 14.6 0.1 0.21 11.2 0.0 2.4 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 CEP12140.1 - 0.03 14.2 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CEP12140.1 - 0.032 13.4 0.0 0.086 12.0 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CEP12140.1 - 0.039 13.6 0.6 0.61 9.7 0.4 2.4 1 1 0 1 1 1 0 NTPase RNA_helicase PF00910.17 CEP12140.1 - 0.048 13.8 0.0 0.29 11.3 0.0 2.4 1 1 0 1 1 1 0 RNA helicase DUF4110 PF13422.1 CEP12140.1 - 2.8 7.8 13.1 0.22 11.3 5.2 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4110) WLM PF08325.5 CEP12141.1 - 2.8e-32 112.0 0.2 4.1e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 CEP12141.1 - 5.9e-10 38.0 14.0 4e-05 22.6 4.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 CEP12141.1 - 0.00098 18.8 6.3 0.0028 17.4 4.4 1.8 1 1 0 1 1 1 1 Double zinc ribbon DUF45 PF01863.12 CEP12141.1 - 0.0019 18.0 0.4 0.0037 17.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Hamartin PF04388.7 CEP12141.1 - 0.0074 15.0 0.2 0.011 14.4 0.1 1.3 1 0 0 1 1 1 1 Hamartin protein SprT-like PF10263.4 CEP12141.1 - 0.01 15.5 0.0 0.01 15.5 0.0 2.7 2 1 0 2 2 2 0 SprT-like family zf-piccolo PF05715.8 CEP12141.1 - 0.47 10.5 8.2 0.24 11.4 2.7 2.5 2 1 1 3 3 3 0 Piccolo Zn-finger OrfB_Zn_ribbon PF07282.6 CEP12141.1 - 1.1 8.9 6.1 5.2 6.8 0.8 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.10 CEP12141.1 - 5.2 6.7 13.3 0.36 10.4 0.3 3.1 1 1 2 3 3 3 0 Sec23/Sec24 zinc finger Sulfate_transp PF00916.15 CEP12142.1 - 2.5e-40 138.2 7.9 2.5e-40 138.2 5.5 1.9 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 CEP12142.1 - 1.7e-13 50.1 0.0 2.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 CEP12142.1 - 1.4e-10 40.6 0.0 3.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain SpoIIE PF07228.7 CEP12144.1 - 5.2e-13 49.1 0.0 1e-12 48.1 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CEP12144.1 - 4.8e-11 42.4 0.0 6.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CEP12144.1 - 4e-09 36.2 0.2 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Mur_ligase_M PF08245.7 CEP12145.1 - 2.7e-11 43.8 0.0 5.7e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CEP12145.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain tRNA_U5-meth_tr PF05958.6 CEP12145.1 - 0.18 10.4 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF647 PF04884.9 CEP12146.1 - 2.5e-54 184.1 0.3 3.6e-54 183.5 0.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DNA_primase_S PF01896.14 CEP12146.1 - 1.1e-50 171.1 0.9 3e-50 169.8 0.7 1.7 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Astro_capsid PF03115.9 CEP12148.1 - 0.16 10.1 0.3 0.19 9.9 0.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Chromo PF00385.19 CEP12149.1 - 0.0003 20.4 0.5 0.00032 20.2 0.3 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Microtub_assoc PF07989.6 CEP12153.1 - 3.8e-18 65.0 5.6 3.8e-18 65.0 3.9 8.2 5 2 5 10 10 10 1 Microtubule associated DUF4200 PF13863.1 CEP12153.1 - 0.0022 17.9 23.0 0.0022 17.9 16.0 7.3 3 2 4 8 8 8 2 Domain of unknown function (DUF4200) DUF3416 PF11896.3 CEP12153.1 - 0.0067 16.3 4.0 0.0067 16.3 2.7 4.7 3 2 2 5 5 5 1 Domain of unknown function (DUF3416) Dynein_heavy PF03028.10 CEP12154.1 - 1.1e-197 658.3 0.1 1.1e-197 658.3 0.0 2.8 3 1 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CEP12154.1 - 5e-192 639.3 15.3 5e-192 639.3 10.6 3.6 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CEP12154.1 - 1.7e-133 445.0 4.0 1.7e-133 445.0 2.7 5.7 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CEP12154.1 - 8.2e-83 277.4 0.0 2.9e-82 275.6 0.0 2.0 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CEP12154.1 - 3.7e-47 160.5 0.1 1e-45 155.7 0.0 3.0 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CEP12154.1 - 3.9e-46 156.7 0.1 1.7e-45 154.6 0.1 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CEP12154.1 - 3.3e-31 108.2 15.1 2.5e-19 69.2 0.0 2.9 1 1 0 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CEP12154.1 - 3.4e-29 101.3 0.0 2.8e-12 46.5 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 CEP12154.1 - 1.2e-17 63.9 0.0 3.5e-17 62.3 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CEP12154.1 - 5.8e-15 55.5 0.0 0.012 15.6 0.0 5.8 5 0 0 5 5 4 3 AAA domain AAA PF00004.24 CEP12154.1 - 3.3e-13 49.9 0.0 0.0096 16.1 0.0 5.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CEP12154.1 - 1.5e-11 44.3 0.3 0.013 15.4 0.0 5.6 5 0 0 5 5 5 3 AAA domain AAA_17 PF13207.1 CEP12154.1 - 3e-10 40.9 0.0 0.11 13.3 0.0 6.0 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 CEP12154.1 - 6.8e-10 39.2 0.0 0.071 13.0 0.0 5.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.1 CEP12154.1 - 5.6e-08 33.1 3.4 0.17 12.1 0.0 6.3 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 CEP12154.1 - 1e-07 31.1 0.0 0.068 12.0 0.0 4.0 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_29 PF13555.1 CEP12154.1 - 1e-06 28.1 0.0 0.15 11.6 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CEP12154.1 - 3.1e-06 26.5 0.2 0.69 9.0 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CEP12154.1 - 4.3e-06 27.0 0.0 0.53 10.5 0.0 5.2 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 CEP12154.1 - 5.9e-06 25.9 0.1 1.2 8.9 0.0 4.7 4 0 0 4 4 4 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CEP12154.1 - 2.4e-05 23.9 0.0 1.1 8.6 0.0 4.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 CEP12154.1 - 0.00019 20.9 0.4 0.22 10.9 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CEP12154.1 - 0.0016 18.5 0.0 2.4 8.3 0.0 4.5 4 0 0 4 4 4 1 RNA helicase AAA_25 PF13481.1 CEP12154.1 - 0.0017 17.7 0.0 1.3 8.3 0.0 4.2 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CEP12154.1 - 0.0025 17.0 0.0 9.7 5.3 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function, DUF258 MobB PF03205.9 CEP12154.1 - 0.007 16.0 0.3 6.7 6.4 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CEP12154.1 - 0.019 14.4 8.0 1.2 8.5 0.0 4.8 5 0 0 5 5 4 0 AAA-like domain PsbW PF07123.7 CEP12155.1 - 0.031 14.3 0.1 0.034 14.2 0.1 1.0 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) HLH PF00010.21 CEP12156.1 - 1.2e-17 63.3 0.6 1.2e-17 63.3 0.4 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Lem_TRP PF08262.6 CEP12156.1 - 1.1 9.1 3.6 2.3 8.1 0.2 2.5 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide MRP-L20 PF12824.2 CEP12157.1 - 0.14 12.0 0.8 0.16 11.9 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Pkinase PF00069.20 CEP12158.1 - 1.4e-56 191.4 0.0 2.7e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12158.1 - 3.1e-20 72.3 0.1 1.3e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CEP12158.1 - 0.00095 18.9 0.2 0.0047 16.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP12158.1 - 0.024 14.2 3.9 0.15 11.5 0.0 3.1 3 0 0 3 3 3 0 Choline/ethanolamine kinase FYVE PF01363.16 CEP12159.1 - 1.2e-13 50.6 12.8 2.5e-13 49.7 7.8 2.4 2 0 0 2 2 2 1 FYVE zinc finger TEA PF01285.13 CEP12160.1 - 5.8e-37 127.8 5.5 1.5e-34 119.9 2.6 2.1 2 0 0 2 2 2 2 TEA/ATTS domain family CLASP_N PF12348.3 CEP12161.1 - 1.8e-54 184.5 0.1 3e-54 183.7 0.1 1.4 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 CEP12161.1 - 0.0053 16.7 0.0 2.3 8.5 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat V-SNARE PF05008.10 CEP12162.1 - 1.6e-08 34.5 0.8 2.2e-08 34.1 0.6 1.2 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus Ran-binding PF05508.6 CEP12162.1 - 0.039 12.8 0.2 0.042 12.7 0.1 1.0 1 0 0 1 1 1 0 RanGTP-binding protein DUF939_C PF11728.3 CEP12162.1 - 0.088 12.6 0.3 0.096 12.4 0.2 1.0 1 0 0 1 1 1 0 DUF939 C-terminal domain DAG_kinase_N PF14513.1 CEP12162.1 - 0.12 12.6 0.0 0.14 12.3 0.0 1.0 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF4119 PF13494.1 CEP12162.1 - 0.2 11.6 1.1 0.32 10.9 0.6 1.5 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) V-SNARE_C PF12352.3 CEP12163.1 - 2.2e-19 69.2 3.0 4.1e-19 68.4 2.1 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CEP12163.1 - 4.9e-09 36.2 3.1 7.5e-08 32.4 0.7 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Fusion_gly PF00523.13 CEP12163.1 - 0.004 15.2 1.1 0.006 14.6 0.8 1.2 1 0 0 1 1 1 1 Fusion glycoprotein F0 DUF4407 PF14362.1 CEP12163.1 - 0.011 14.6 0.5 0.013 14.4 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rifin_STEVOR PF02009.11 CEP12163.1 - 0.025 14.2 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Sec20 PF03908.8 CEP12163.1 - 0.046 13.4 0.2 0.094 12.4 0.1 1.6 1 1 0 1 1 1 0 Sec20 ODV-E18 PF10717.4 CEP12163.1 - 0.05 13.0 0.4 0.085 12.3 0.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Ribosomal_S8 PF00410.14 CEP12163.1 - 0.059 13.2 0.1 0.13 12.0 0.0 1.6 1 1 1 2 2 2 0 Ribosomal protein S8 Synaptobrevin PF00957.16 CEP12163.1 - 0.54 9.9 4.3 0.56 9.8 0.3 2.5 3 0 0 3 3 3 0 Synaptobrevin Rad51 PF08423.6 CEP12164.1 - 4e-132 438.8 0.8 5e-132 438.5 0.5 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CEP12164.1 - 3.3e-13 49.4 0.0 5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CEP12164.1 - 2.4e-09 36.7 0.2 3.4e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CEP12164.1 - 1.6e-08 33.9 0.0 2.6e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 CEP12164.1 - 3.3e-08 33.5 0.2 1.1e-07 31.9 0.1 1.9 1 1 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.10 CEP12164.1 - 0.011 14.6 0.1 0.076 11.8 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 CEP12164.1 - 0.03 13.1 0.1 0.051 12.4 0.1 1.3 1 0 0 1 1 1 0 PAXNEB protein AAA_22 PF13401.1 CEP12164.1 - 0.032 14.3 0.1 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.13 CEP12165.1 - 2.9e-09 36.6 13.8 2.9e-09 36.6 9.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bestrophin PF01062.16 CEP12168.1 - 4.2e-52 176.9 0.6 6.8e-34 117.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel FHA PF00498.21 CEP12170.1 - 1.9e-16 59.9 0.0 2.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 FHA domain Bile_Hydr_Trans PF04775.9 CEP12170.1 - 0.14 11.8 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region DUF2763 PF10961.3 CEP12171.1 - 0.13 12.6 0.0 0.44 10.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2763) B56 PF01603.15 CEP12172.1 - 1.4e-168 560.7 7.4 1.8e-168 560.4 5.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Ecm29 PF13001.2 CEP12173.1 - 5.4e-129 430.9 0.1 1.3e-128 429.6 0.1 1.7 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 CEP12173.1 - 6.1e-14 50.7 11.1 0.025 14.6 0.0 12.2 14 0 0 14 14 14 3 HEAT repeat HEAT_2 PF13646.1 CEP12173.1 - 5.4e-12 45.8 6.4 1.9 8.8 0.0 9.3 8 2 2 10 10 10 5 HEAT repeats HEAT_EZ PF13513.1 CEP12173.1 - 6.7e-09 35.9 8.0 1.3 9.5 0.1 9.3 7 1 1 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CEP12173.1 - 3e-06 27.5 4.6 0.32 11.4 0.0 7.1 7 2 3 10 10 10 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 CEP12173.1 - 0.035 13.9 0.0 1 9.2 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HLH PF00010.21 CEP12174.1 - 3.9e-09 36.0 0.1 7.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RVT_1 PF00078.22 CEP12175.1 - 3.3e-21 75.6 0.0 4.4e-13 49.0 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) S4 PF01479.20 CEP12175.1 - 6.3e-16 57.5 0.0 1.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CEP12175.1 - 0.0014 18.1 0.0 0.0036 16.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain MatE PF01554.13 CEP12176.1 - 9.5e-52 174.8 28.1 5.7e-26 91.0 5.3 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 CEP12176.1 - 4.3e-08 33.0 6.5 4.3e-08 33.0 4.5 4.0 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain LCAT PF02450.10 CEP12178.1 - 7.2e-79 265.5 0.0 3.4e-78 263.3 0.0 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 CEP12178.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family NUDIX PF00293.23 CEP12179.1 - 3e-15 56.0 0.0 5.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.8 CEP12179.1 - 1.3e-13 50.6 1.3 3e-09 36.6 0.1 2.6 1 1 1 2 2 2 2 Dcp2, box A domain HSDR_N_2 PF13588.1 CEP12180.1 - 0.0031 17.3 0.1 0.0049 16.6 0.1 1.4 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) RF-1 PF00472.15 CEP12181.1 - 7e-40 135.3 3.2 1.2e-39 134.5 2.2 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CEP12181.1 - 1.7e-32 111.5 1.8 2.8e-32 110.8 0.2 2.1 2 0 0 2 2 2 1 PCRF domain FliT PF05400.8 CEP12181.1 - 0.089 13.2 9.5 0.49 10.8 0.3 3.4 2 1 1 3 3 3 0 Flagellar protein FliT AATF-Che1 PF13339.1 CEP12181.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.7 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor Kinesin PF00225.18 CEP12182.1 - 5.7e-113 377.0 2.0 5.7e-113 377.0 1.4 2.4 3 1 0 3 3 3 1 Kinesin motor domain AAA_10 PF12846.2 CEP12182.1 - 0.39 10.1 0.0 0.39 10.1 0.0 4.1 3 1 0 3 3 3 0 AAA-like domain DUF2031 PF09592.5 CEP12183.1 - 0.1 11.6 1.4 0.24 10.5 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) F-box-like PF12937.2 CEP12184.1 - 0.00061 19.4 1.1 0.0011 18.6 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 CEP12184.1 - 0.073 12.7 2.3 0.2 11.4 1.6 2.0 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.28 CEP12184.1 - 3.3 7.4 6.0 11 5.8 4.1 1.9 1 1 0 1 1 1 0 F-box domain IMS PF00817.15 CEP12185.1 - 7e-36 123.2 0.0 1.2e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CEP12185.1 - 2e-14 53.6 0.0 8.8e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain SR-25 PF10500.4 CEP12185.1 - 0.02 14.3 7.9 0.044 13.2 5.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMS_HHH PF11798.3 CEP12185.1 - 0.091 12.8 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif SH3_9 PF14604.1 CEP12186.1 - 2.1e-09 36.8 0.0 3.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP12186.1 - 0.00021 20.5 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain CD99L2 PF12301.3 CEP12186.1 - 0.0067 16.1 0.4 0.019 14.6 0.3 1.7 1 0 0 1 1 1 1 CD99 antigen like protein 2 SH3_2 PF07653.12 CEP12186.1 - 0.0096 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Alpha_GJ PF03229.8 CEP12186.1 - 0.019 15.2 8.0 0.019 15.2 5.6 3.0 2 1 1 3 3 3 0 Alphavirus glycoprotein J tRNA_anti-like PF12869.2 CEP12186.1 - 0.021 14.3 0.3 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 tRNA_anti-like Herpes_gE PF02480.11 CEP12186.1 - 0.032 12.4 2.1 0.045 12.0 0.0 1.9 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CEP12186.1 - 0.1 13.0 0.1 0.89 9.9 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 CEP12186.1 - 0.23 11.6 10.3 0.042 14.0 1.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2500 PF10694.4 CEP12186.1 - 1.3 9.1 3.6 6.9 6.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2500) zf-C2H2_4 PF13894.1 CEP12187.1 - 0.00013 21.9 11.8 0.026 14.8 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP12187.1 - 0.0027 17.9 16.9 0.044 14.1 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP12187.1 - 0.036 14.3 12.0 0.25 11.7 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CEP12187.1 - 0.053 13.6 0.3 17 5.7 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CPSase_L_D2 PF02786.12 CEP12188.1 - 2.9e-113 376.3 0.5 4.4e-84 280.9 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 CEP12188.1 - 1.6e-45 154.8 0.0 3e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 CEP12188.1 - 4.5e-45 152.3 0.0 1.1e-44 151.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 CEP12188.1 - 3.2e-43 146.7 0.0 6.5e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 CEP12188.1 - 3e-41 139.9 0.0 4.1e-21 75.1 0.0 3.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CEP12188.1 - 7.2e-41 138.8 0.0 2.7e-40 136.9 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 CEP12188.1 - 2.9e-37 127.9 0.1 1.2e-36 126.0 0.0 2.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CEP12188.1 - 3.4e-35 121.4 0.2 9.2e-23 80.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP12188.1 - 7e-23 80.8 0.1 7.9e-12 44.5 0.0 3.5 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CEP12188.1 - 2.6e-19 68.9 0.0 1.8e-18 66.2 0.0 2.6 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 CEP12188.1 - 4.9e-16 58.7 0.9 5.6e-09 35.6 0.1 2.7 2 1 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CEP12188.1 - 2.1e-15 56.5 0.2 5.8e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 CEP12188.1 - 4.4e-08 33.1 1.0 0.002 18.0 0.0 3.3 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.8 CEP12188.1 - 3.5e-05 23.3 0.1 0.00063 19.2 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 MULE PF10551.4 CEP12189.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF2765 PF10963.3 CEP12189.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2765) ERp29 PF07749.7 CEP12191.1 - 0.14 12.7 2.5 0.22 12.1 1.8 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain ADH_N PF08240.7 CEP12194.1 - 2.6e-31 107.6 2.8 2.6e-31 107.6 2.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP12194.1 - 2.3e-15 56.2 0.1 4.2e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 CEP12194.1 - 0.00042 18.8 0.4 0.00064 18.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Methyltransf_18 PF12847.2 CEP12194.1 - 0.001 19.6 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.14 CEP12194.1 - 0.0016 17.6 0.5 0.0067 15.5 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CEP12194.1 - 0.0025 18.1 0.2 0.0057 17.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CEP12194.1 - 0.003 17.7 0.0 0.0076 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 CEP12194.1 - 0.0039 16.7 0.4 0.013 15.0 0.1 1.8 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 CEP12194.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 CEP12194.1 - 0.011 14.7 0.3 0.017 14.0 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP12194.1 - 0.015 15.2 0.1 0.032 14.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ADH_zinc_N_2 PF13602.1 CEP12194.1 - 0.018 15.9 0.0 0.083 13.7 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 CEP12194.1 - 0.022 14.6 0.4 0.054 13.3 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YdfZ PF14001.1 CEP12194.1 - 0.045 14.0 0.0 0.21 11.9 0.0 2.2 1 1 0 1 1 1 0 YdfZ protein XdhC_C PF13478.1 CEP12194.1 - 0.063 13.5 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.13 CEP12194.1 - 0.084 12.5 0.5 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 CEP12195.1 - 8e-14 51.0 8.7 8.6e-11 41.0 3.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP12195.1 - 0.00018 20.3 2.2 0.00028 19.7 1.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 CEP12195.1 - 0.0042 17.0 0.9 0.0072 16.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) Aph-1 PF06105.7 CEP12195.1 - 0.027 13.7 0.5 0.035 13.3 0.3 1.3 1 0 0 1 1 1 0 Aph-1 protein YbhQ PF11076.3 CEP12195.1 - 0.052 13.1 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ Spc97_Spc98 PF04130.8 CEP12196.1 - 4.9e-68 229.7 19.7 1.1e-67 228.6 13.6 1.6 1 0 0 1 1 1 1 Spc97 / Spc98 family Adeno_E1B_19K PF01691.11 CEP12196.1 - 0.031 13.5 3.4 1.9 7.7 0.1 3.1 3 0 0 3 3 3 0 Adenovirus E1B 19K protein / small t-antigen YvfG PF09628.5 CEP12196.1 - 0.052 13.6 0.5 4.7 7.4 0.1 3.4 1 1 2 3 3 3 0 YvfG protein Ribosomal_L30 PF00327.15 CEP12197.1 - 1.3e-11 43.8 0.1 1.8e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e nsp8 PF08717.5 CEP12198.1 - 0.036 13.6 1.5 0.063 12.8 1.1 1.3 1 0 0 1 1 1 0 nsp8 replicase Pox_D5 PF03288.11 CEP12198.1 - 0.17 12.1 1.8 0.4 10.9 0.3 2.1 1 1 1 2 2 2 0 Poxvirus D5 protein-like RVT_1 PF00078.22 CEP12199.1 - 2.5e-28 98.9 0.1 6.7e-28 97.5 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP12199.1 - 1e-08 34.7 0.3 3.1e-08 33.2 0.2 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP12199.1 - 2.9e-08 33.9 0.7 5.2e-08 33.1 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.1 CEP12199.1 - 1.5 8.5 10.0 0.039 13.6 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 CEP12199.1 - 8.3 6.0 10.4 0.068 12.6 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle Polysacc_deac_1 PF01522.16 CEP12201.1 - 7.9e-38 128.8 0.0 1.9e-37 127.6 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase TRAM_LAG1_CLN8 PF03798.11 CEP12201.1 - 1.5e-33 116.0 22.8 2.8e-33 115.1 15.8 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 CEP12201.1 - 5.7e-14 51.3 0.7 5.7e-14 51.3 0.5 2.1 2 0 0 2 2 2 1 TRAM1-like protein Glyco_hydro_57 PF03065.10 CEP12201.1 - 1.5e-05 24.1 0.1 2.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 CobT PF06213.7 CEP12201.1 - 0.002 17.3 7.4 0.002 17.3 5.1 2.2 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT TLP-20 PF06088.6 CEP12201.1 - 0.044 13.4 11.4 0.67 9.5 2.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) nec1 PF10379.4 CEP12201.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Virulence protein nec1 DUF1510 PF07423.6 CEP12201.1 - 0.28 10.4 19.9 0.052 12.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 CEP12201.1 - 4.4 6.9 0.0 4.4 6.9 0.0 3.3 2 1 1 3 3 3 0 FAM176 family GCS PF03074.11 CEP12203.1 - 3.1e-181 602.3 0.4 4.6e-181 601.7 0.3 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 CEP12203.1 - 0.012 14.7 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) LRR_4 PF12799.2 CEP12204.1 - 1.2e-05 24.8 1.2 0.016 14.8 0.1 4.4 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CEP12204.1 - 1.2e-05 24.8 4.2 0.27 11.4 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.1 CEP12204.1 - 0.00018 21.2 0.9 1.5 8.6 0.1 4.3 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CEP12204.1 - 0.017 15.0 3.5 38 4.8 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat GalP_UDP_transf PF01087.17 CEP12207.1 - 2.7e-71 239.3 2.6 1.8e-70 236.6 0.7 2.5 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CEP12207.1 - 1.3e-60 203.7 0.0 2.7e-60 202.7 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 CEP12207.1 - 0.00017 21.8 0.0 0.00043 20.4 0.0 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CEP12207.1 - 0.00046 20.6 0.0 0.0027 18.2 0.0 2.0 2 0 0 2 2 2 1 HIT domain Fungal_trans PF04082.13 CEP12208.1 - 2.4e-24 85.6 1.1 3.7e-24 84.9 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP12208.1 - 1.3e-07 31.3 12.0 2.2e-07 30.6 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pap_E4 PF02711.9 CEP12208.1 - 1.8 9.4 7.7 0.53 11.1 2.7 2.1 2 0 0 2 2 2 0 E4 protein Ank_5 PF13857.1 CEP12209.1 - 1.1e-06 28.6 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_jaz PF12171.3 CEP12209.1 - 0.021 14.9 0.1 0.057 13.5 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SRP14 PF02290.10 CEP12209.1 - 0.092 12.6 3.2 0.44 10.4 1.7 2.6 2 0 0 2 2 2 0 Signal recognition particle 14kD protein Cyclin PF08613.6 CEP12210.1 - 7.5e-39 133.5 1.1 9.6e-39 133.1 0.8 1.1 1 0 0 1 1 1 1 Cyclin Calc_CGRP_IAPP PF00214.14 CEP12210.1 - 0.014 15.3 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Cyclin_N PF00134.18 CEP12210.1 - 0.062 12.8 0.4 0.14 11.7 0.3 1.8 1 1 0 1 1 1 0 Cyclin, N-terminal domain DUF1065 PF06358.6 CEP12210.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) TIP41 PF04176.8 CEP12211.1 - 7.2e-66 220.9 1.7 9.2e-66 220.5 1.2 1.1 1 0 0 1 1 1 1 TIP41-like family ATE_C PF04377.10 CEP12212.1 - 1.1e-46 157.9 6.5 2.2e-46 157.0 4.5 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CEP12212.1 - 6.7e-29 99.5 1.2 2.4e-28 97.7 0.7 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus PhyH PF05721.8 CEP12213.1 - 8.9e-10 38.9 0.1 1.4e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DsbC_N PF10411.4 CEP12213.1 - 0.093 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Sec1 PF00995.18 CEP12214.1 - 8e-164 546.3 3.1 9.1e-164 546.1 2.2 1.0 1 0 0 1 1 1 1 Sec1 family Phage_int_SAM_1 PF02899.12 CEP12215.1 - 0.00044 20.3 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 CEP12215.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DASH_Ask1 PF08655.5 CEP12216.1 - 2.7e-19 68.7 0.1 5.3e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 ERG4_ERG24 PF01222.12 CEP12217.1 - 1.7e-155 517.8 8.9 2.4e-155 517.3 6.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DnaJ PF00226.26 CEP12217.1 - 1.5e-17 63.0 0.0 3.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1295 PF06966.7 CEP12217.1 - 5.3e-05 22.6 0.1 0.00012 21.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Aldedh PF00171.17 CEP12218.1 - 3.4e-188 625.6 0.1 4e-188 625.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CEP12218.1 - 0.00035 19.8 0.0 0.31 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Ribosomal_S27 PF01599.14 CEP12219.1 - 8.7e-28 95.9 2.3 1.8e-27 94.8 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 CEP12219.1 - 1.4e-17 62.8 0.0 2.4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CEP12219.1 - 1e-09 37.9 0.0 2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 CEP12219.1 - 0.013 15.3 0.7 0.022 14.6 0.5 1.4 1 0 0 1 1 1 0 IBR domain Telomere_Sde2 PF13019.1 CEP12219.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Telomere stability and silencing Ubiquitin_2 PF14560.1 CEP12219.1 - 0.11 12.7 0.0 0.42 10.9 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain TPR_11 PF13414.1 CEP12220.1 - 7.9e-35 118.3 19.1 4.7e-15 55.0 0.7 4.5 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 CEP12220.1 - 1.2e-25 88.0 18.1 1e-05 24.8 0.2 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12220.1 - 8.6e-21 72.1 16.5 0.00035 20.2 0.1 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 CEP12220.1 - 4.4e-17 61.7 14.8 3.6e-10 39.6 0.5 4.3 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP12220.1 - 1.1e-08 34.9 1.1 0.67 10.7 0.0 6.2 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP12220.1 - 2.2e-08 33.6 4.5 0.05 13.8 0.1 5.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP12220.1 - 8.2e-08 32.4 7.9 0.014 15.7 0.0 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP12220.1 - 1.7e-07 31.2 13.4 3.4e-05 23.8 1.0 3.8 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CEP12220.1 - 6.4e-07 28.7 9.7 4.8e-05 22.8 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP12220.1 - 2.9e-06 27.7 8.7 0.13 12.9 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP12220.1 - 1e-05 24.9 23.8 0.0029 17.2 0.2 6.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 CEP12220.1 - 0.0034 17.1 1.1 0.46 10.3 0.1 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 CEP12220.1 - 0.015 15.2 0.2 0.015 15.2 0.2 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP12220.1 - 0.035 14.5 5.7 3.9 8.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2999 PF11212.3 CEP12220.1 - 0.071 13.1 1.6 8.7 6.4 0.4 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF2999) ESCRT-II PF05871.7 CEP12220.1 - 0.21 11.4 1.2 1.1 9.1 0.1 2.3 2 1 0 2 2 2 0 ESCRT-II complex subunit RPN7 PF10602.4 CEP12220.1 - 1.7 8.0 8.2 0.33 10.2 0.1 3.1 1 1 2 3 3 3 0 26S proteasome subunit RPN7 DUF4110 PF13422.1 CEP12220.1 - 7.6 6.4 9.9 0.49 10.2 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4110) Pkinase PF00069.20 CEP12223.1 - 8.3e-70 234.8 0.0 2e-69 233.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12223.1 - 1.8e-40 138.6 0.0 3.8e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP12223.1 - 1.4e-08 34.0 0.0 7.8e-08 31.6 0.0 2.2 3 0 0 3 3 3 1 Kinase-like EAP30 PF04157.11 CEP12224.1 - 4e-49 166.7 1.2 6e-49 166.2 0.9 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CEP12224.1 - 5.1e-26 90.3 0.0 1e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 CEP12224.1 - 8e-05 21.6 19.4 0.00023 20.1 1.1 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 CEP12224.1 - 0.00029 20.5 7.3 0.0016 18.2 5.4 1.9 1 1 1 2 2 2 2 Double zinc ribbon GRAM PF02893.15 CEP12224.1 - 0.0042 16.5 0.2 0.016 14.6 0.0 2.1 3 0 0 3 3 3 1 GRAM domain OrfB_Zn_ribbon PF07282.6 CEP12224.1 - 0.17 11.5 9.1 0.51 10.0 1.0 2.8 1 1 1 2 2 2 0 Putative transposase DNA-binding domain GCC2_GCC3 PF07699.8 CEP12224.1 - 1.1 8.9 12.0 8.3 6.0 4.0 2.5 1 1 1 2 2 2 0 GCC2 and GCC3 PolC_DP2 PF03833.8 CEP12224.1 - 3.3 5.2 5.2 0.57 7.7 1.1 1.6 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 HMG_box PF00505.14 CEP12225.1 - 5e-21 74.7 2.4 1.1e-20 73.6 1.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP12225.1 - 6.9e-07 29.5 1.5 6.9e-07 29.5 1.0 1.7 2 0 0 2 2 2 1 HMG-box domain eRF1_1 PF03463.10 CEP12227.1 - 1.2e-48 163.9 0.0 2.1e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 CEP12227.1 - 3.6e-30 104.9 0.2 5.6e-30 104.3 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CEP12227.1 - 1.4e-24 86.4 0.0 3.6e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 Hexokinase_2 PF03727.11 CEP12229.1 - 4.1e-74 248.8 1.2 6e-74 248.3 0.8 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEP12229.1 - 2.8e-67 226.0 0.1 4.4e-67 225.3 0.1 1.3 1 0 0 1 1 1 1 Hexokinase DUF1924 PF09086.6 CEP12229.1 - 0.047 13.7 0.0 2.3 8.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) DUF4434 PF14488.1 CEP12229.1 - 0.11 12.2 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) ABC_tran PF00005.22 CEP12230.1 - 3.4e-40 137.4 0.0 9.1e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CEP12230.1 - 1.3e-13 51.6 6.1 0.0041 17.1 0.1 4.1 2 2 0 3 3 3 3 AAA domain AAA_22 PF13401.1 CEP12230.1 - 1.7e-06 28.2 0.3 0.085 13.0 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEP12230.1 - 4.7e-06 26.0 0.0 0.0029 17.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CEP12230.1 - 1.5e-05 25.0 0.0 0.073 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CEP12230.1 - 3.2e-05 24.1 0.4 0.61 10.3 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CEP12230.1 - 4.4e-05 23.9 1.1 0.013 15.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 CEP12230.1 - 4.4e-05 24.2 0.1 0.22 12.3 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CEP12230.1 - 9.6e-05 22.2 0.1 0.63 9.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEP12230.1 - 0.0001 21.5 0.0 0.31 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CEP12230.1 - 0.00014 22.1 0.1 2.2 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 CEP12230.1 - 0.00016 20.9 0.2 0.26 10.4 0.1 3.2 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 CEP12230.1 - 0.00017 21.0 0.7 0.96 8.8 0.0 3.5 4 0 0 4 4 3 1 IstB-like ATP binding protein Dynamin_N PF00350.18 CEP12230.1 - 0.0002 21.2 0.1 0.029 14.1 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AAA_25 PF13481.1 CEP12230.1 - 0.0003 20.2 0.8 0.73 9.1 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CEP12230.1 - 0.0003 20.6 0.0 0.45 10.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CEP12230.1 - 0.00036 20.0 0.0 0.31 10.5 0.0 2.7 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CEP12230.1 - 0.0011 18.4 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CEP12230.1 - 0.0016 18.8 0.0 3.5 8.1 0.0 3.2 3 0 0 3 3 2 0 Miro-like protein MobB PF03205.9 CEP12230.1 - 0.0021 17.7 0.1 0.87 9.2 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CEP12230.1 - 0.0026 17.4 0.2 1.3 8.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CEP12230.1 - 0.003 17.2 0.1 0.65 9.6 0.0 3.1 3 0 0 3 3 3 1 NACHT domain MMR_HSR1 PF01926.18 CEP12230.1 - 0.0032 17.3 0.0 3.3 7.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.1 CEP12230.1 - 0.0047 16.5 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP12230.1 - 0.006 16.5 0.3 2.7 7.9 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 CEP12230.1 - 0.008 15.1 0.8 1.4 7.7 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 CEP12230.1 - 0.012 15.1 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 CEP12230.1 - 0.012 15.1 0.0 6.5 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CEP12230.1 - 0.015 14.2 0.1 5.7 5.7 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain AAA_PrkA PF08298.6 CEP12230.1 - 0.016 13.8 0.0 0.084 11.5 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain Arch_ATPase PF01637.13 CEP12230.1 - 0.019 14.6 0.0 8 6.0 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase SRPRB PF09439.5 CEP12230.1 - 0.027 13.7 0.4 6.1 6.0 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 CEP12230.1 - 0.027 13.5 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 CEP12230.1 - 0.029 14.2 0.0 1.2 9.1 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 CEP12230.1 - 0.029 12.8 0.3 4 5.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 CEP12230.1 - 0.031 13.3 1.1 2.7 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Arf PF00025.16 CEP12230.1 - 0.034 13.3 0.0 9.6 5.4 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP-synt_ab PF00006.20 CEP12230.1 - 0.034 13.6 0.0 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain GTP_EFTU PF00009.22 CEP12230.1 - 0.04 13.3 0.0 0.6 9.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ADK PF00406.17 CEP12230.1 - 0.054 13.3 0.1 2.2 8.1 0.0 2.6 2 1 0 2 2 2 0 Adenylate kinase NTPase_1 PF03266.10 CEP12230.1 - 0.064 12.9 0.8 37 3.9 0.0 3.4 3 0 0 3 3 3 0 NTPase Mg_chelatase PF01078.16 CEP12230.1 - 0.093 11.8 0.0 9.2 5.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CEP12230.1 - 0.094 12.3 0.0 9.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Mito_carr PF00153.22 CEP12231.1 - 2.5e-54 180.9 0.1 1.2e-18 66.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Choline_transpo PF04515.7 CEP12232.1 - 5e-79 265.4 38.7 5e-79 265.4 26.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 CEP12232.1 - 0.73 9.8 7.3 5 7.1 5.1 2.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zn_clus PF00172.13 CEP12233.1 - 8.4e-10 38.4 10.0 1.5e-09 37.6 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYVE PF01363.16 CEP12234.1 - 1.1e-10 41.1 21.6 3.3e-10 39.7 11.7 3.4 2 1 0 2 2 2 1 FYVE zinc finger NMN_transporter PF04973.7 CEP12234.1 - 0.23 10.9 0.5 0.47 9.8 0.4 1.4 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter MMS1_N PF10433.4 CEP12236.1 - 7.5e-67 225.5 1.1 1.6e-66 224.5 0.7 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 CEP12236.1 - 5.1e-56 190.1 0.8 1.2e-54 185.6 0.1 3.1 3 0 0 3 3 3 1 CPSF A subunit region Dus PF01207.12 CEP12237.1 - 1.4e-56 191.6 0.1 2.7e-56 190.6 0.1 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 CEP12237.1 - 0.00089 18.1 0.0 0.28 9.9 0.0 2.2 1 1 1 2 2 2 2 FMN-dependent dehydrogenase DUF1863 PF08937.6 CEP12237.1 - 0.027 14.5 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Nbas_N PF15492.1 CEP12237.1 - 0.032 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal CHCH PF06747.8 CEP12240.1 - 5.6e-06 26.1 13.0 5.8e-06 26.0 3.0 2.3 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 CEP12240.1 - 1.5 8.6 11.8 1.9 8.3 2.5 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CEP12240.1 - 7.3 6.7 11.5 22 5.1 0.7 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 AAA PF00004.24 CEP12241.1 - 1.1e-43 148.5 0.0 1.9e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CEP12241.1 - 4.7e-07 29.8 0.0 1.4e-06 28.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CEP12241.1 - 6.4e-07 29.1 0.1 1.7e-05 24.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEP12241.1 - 2.7e-06 26.5 0.0 5.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEP12241.1 - 3.6e-06 27.0 0.1 0.00014 21.9 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CEP12241.1 - 3.9e-06 27.0 0.1 0.0012 18.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 CEP12241.1 - 0.00024 20.7 0.1 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CEP12241.1 - 0.00024 21.8 0.7 0.00089 20.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CEP12241.1 - 0.00036 19.5 0.0 0.00088 18.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CEP12241.1 - 0.00099 18.9 0.0 0.004 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CEP12241.1 - 0.0011 18.5 0.3 0.0022 17.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CEP12241.1 - 0.0013 17.9 0.0 0.0034 16.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CEP12241.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CEP12241.1 - 0.0026 16.5 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CEP12241.1 - 0.003 17.0 0.1 0.0057 16.0 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CEP12241.1 - 0.0051 17.1 0.0 0.014 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CEP12241.1 - 0.0058 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.6 CEP12241.1 - 0.0082 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CEP12241.1 - 0.0089 15.1 0.2 0.027 13.5 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 CEP12241.1 - 0.013 14.9 0.3 0.066 12.5 0.2 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CEP12241.1 - 0.014 14.8 0.1 0.054 12.9 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 CEP12241.1 - 0.018 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP12241.1 - 0.03 13.9 0.1 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 CEP12241.1 - 0.031 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CEP12241.1 - 0.047 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 CEP12241.1 - 0.05 12.7 0.3 0.21 10.6 0.0 2.2 2 1 1 3 3 3 0 KaiC UPF0079 PF02367.12 CEP12241.1 - 0.051 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CEP12241.1 - 0.073 12.7 0.0 0.27 10.8 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase ResIII PF04851.10 CEP12241.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 CEP12241.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 CEP12241.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CEP12241.1 - 0.16 11.5 0.1 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTF2 PF02136.15 CEP12242.1 - 3.3e-07 30.6 0.0 9.5e-06 25.9 0.0 2.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 CEP12242.1 - 1.1e-05 24.9 7.0 0.00053 19.5 0.3 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CEP12242.1 - 0.0011 18.5 0.1 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CEP12242.1 - 0.0031 17.2 1.9 0.0064 16.2 0.3 2.1 2 0 0 2 2 2 1 Leucine rich repeat Fructosamin_kin PF03881.9 CEP12243.1 - 4.8e-69 232.5 0.0 5.6e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 CEP12243.1 - 2.5e-11 43.7 0.0 3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CEP12243.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase zf-H2C2_2 PF13465.1 CEP12247.1 - 3.7e-05 23.7 4.3 0.0053 16.9 0.4 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP12247.1 - 4.8e-05 23.3 16.0 0.035 14.4 3.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP12247.1 - 0.0084 16.3 18.1 0.4 11.1 3.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 CEP12247.1 - 0.11 12.5 10.2 0.24 11.5 7.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CEP12247.1 - 6.2 6.9 11.9 1.4 9.0 1.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sugar_tr PF00083.19 CEP12248.1 - 1.1e-107 360.4 21.7 1.2e-70 238.3 2.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP12248.1 - 7.1e-19 67.7 9.6 7.1e-19 67.7 6.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SNF2_N PF00176.18 CEP12249.1 - 7.8e-50 169.3 0.3 9.8e-49 165.7 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 CEP12249.1 - 4.5e-06 26.2 7.7 8.3e-06 25.3 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP12249.1 - 5.5e-05 23.0 11.3 0.00011 22.1 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP12249.1 - 0.00019 21.2 10.0 0.00046 19.9 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CEP12249.1 - 0.00019 20.9 10.3 0.00041 19.9 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP12249.1 - 0.0013 18.4 10.1 0.0025 17.4 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Phenol_Hydrox PF02332.13 CEP12249.1 - 0.0018 17.5 0.3 0.0037 16.5 0.2 1.5 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase Helicase_C PF00271.26 CEP12249.1 - 0.0023 17.7 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 CEP12249.1 - 0.2 11.5 8.4 0.47 10.3 5.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ricin_B_lectin PF00652.17 CEP12250.1 - 3.1e-16 59.5 0.1 2.1e-08 34.2 0.7 3.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP12250.1 - 1.8e-15 57.1 4.1 1.9e-09 37.8 0.7 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SAM_decarbox PF01536.11 CEP12251.1 - 5.1e-97 324.5 2.3 1.7e-55 187.9 0.2 3.0 2 1 1 3 3 3 3 Adenosylmethionine decarboxylase DHC PF09626.5 CEP12251.1 - 0.072 13.7 1.3 0.18 12.5 0.9 1.7 1 0 0 1 1 1 0 Dihaem cytochrome c Asp PF00026.18 CEP12253.1 - 8.5e-32 110.6 0.0 1.2e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP12253.1 - 0.00038 20.4 0.1 0.0008 19.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP12253.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Kelch_4 PF13418.1 CEP12254.1 - 4e-13 48.9 16.7 5.3e-05 22.8 0.1 6.4 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP12254.1 - 5.6e-13 48.6 8.9 1.8e-07 31.1 0.0 6.3 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP12254.1 - 1.4e-09 37.7 4.9 1.2e-06 28.2 0.1 5.3 6 0 0 6 6 6 1 Kelch motif Kelch_6 PF13964.1 CEP12254.1 - 5.3e-06 26.3 19.7 7.9e-05 22.6 0.2 7.1 8 0 0 8 8 8 1 Kelch motif Kelch_2 PF07646.10 CEP12254.1 - 3.2e-05 23.5 5.8 0.02 14.6 0.0 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 CEP12254.1 - 0.00028 20.3 17.4 0.00029 20.2 0.2 5.0 5 1 0 5 5 5 2 Kelch motif ASC PF00858.19 CEP12254.1 - 0.19 10.3 7.2 0.62 8.6 0.1 2.5 3 0 0 3 3 3 0 Amiloride-sensitive sodium channel DRIM PF07539.7 CEP12255.1 - 4.3e-44 149.3 0.1 3.6e-43 146.3 0.0 2.8 2 0 0 2 2 2 1 Down-regulated in metastasis PPR_2 PF13041.1 CEP12256.1 - 1.2e-31 108.4 17.5 2.4e-12 46.6 0.0 7.5 3 3 5 8 8 8 7 PPR repeat family PPR_3 PF13812.1 CEP12256.1 - 9.2e-27 91.0 0.3 0.0027 17.8 0.0 8.0 8 1 0 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.15 CEP12256.1 - 3.6e-23 79.8 8.0 0.00038 20.2 0.0 7.4 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.2 CEP12256.1 - 4.2e-21 74.1 4.4 0.00014 21.2 0.0 7.3 7 1 1 8 8 8 5 PPR repeat ECSIT PF06239.6 CEP12256.1 - 5.9e-06 25.3 2.5 0.038 12.8 0.0 3.5 2 1 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway Clr5 PF14420.1 CEP12256.1 - 0.008 16.0 1.1 0.065 13.1 0.0 2.7 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 CEP12256.1 - 0.018 14.9 0.1 11 6.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4479 PF14794.1 CEP12256.1 - 0.021 14.3 0.7 0.53 9.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) ATP13 PF12921.2 CEP12256.1 - 0.029 13.7 0.1 2.5 7.4 0.0 3.2 2 1 0 2 2 2 0 Mitochondrial ATPase expression TPR_8 PF13181.1 CEP12256.1 - 0.066 13.0 0.0 1.3 8.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3488 PF11992.3 CEP12257.1 - 0.0013 17.4 4.5 0.0017 17.0 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3488) DUF3367 PF11847.3 CEP12257.1 - 0.0097 13.9 0.1 0.017 13.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3367) Elongin_A PF06881.6 CEP12258.1 - 0.00044 20.6 0.3 0.00075 19.8 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.28 CEP12258.1 - 0.00077 19.0 0.4 0.027 14.1 0.0 2.7 2 0 0 2 2 2 1 F-box domain EF-hand_7 PF13499.1 CEP12258.1 - 0.003 17.6 0.3 0.016 15.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair F-box-like PF12937.2 CEP12258.1 - 0.0034 17.0 0.1 0.042 13.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like EF-hand_1 PF00036.27 CEP12258.1 - 0.023 13.9 0.7 0.066 12.5 0.5 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 CEP12258.1 - 0.084 12.8 0.5 0.084 12.8 0.3 2.0 2 0 0 2 2 2 0 EF-hand domain Lyase_8 PF02278.13 CEP12259.1 - 1.1e-29 103.6 2.4 2.2e-29 102.7 1.7 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 CEP12259.1 - 9.8e-29 100.2 0.2 1.8e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 CEP12259.1 - 8.6e-09 35.2 0.4 3.5e-08 33.3 0.3 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Pox_VP8_L4R PF04498.7 CEP12259.1 - 0.066 12.5 0.0 8.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Poxvirus nucleic acid binding protein VP8/L4R LRR_4 PF12799.2 CEP12260.1 - 7.5e-22 76.5 10.0 6e-09 35.3 0.2 4.3 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP12260.1 - 1.5e-19 69.4 13.4 7.2e-09 35.2 1.7 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CEP12260.1 - 7e-13 46.6 3.2 0.012 15.4 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 CEP12260.1 - 2.2e-08 32.9 6.7 0.073 13.2 0.1 6.2 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 CEP12260.1 - 0.00035 20.3 3.4 7 7.0 0.1 5.6 6 0 0 6 6 6 1 Leucine Rich repeat Alba PF01918.16 CEP12261.1 - 2.8e-12 46.0 1.2 4.6e-12 45.3 0.9 1.4 1 0 0 1 1 1 1 Alba DUF1041 PF06292.12 CEP12261.1 - 0.017 15.3 1.1 0.03 14.5 0.4 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1041) Rpp20 PF12328.3 CEP12261.1 - 0.55 9.8 3.5 0.8 9.3 2.4 1.4 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P S10_plectin PF03501.10 CEP12262.1 - 5.5e-42 141.5 0.1 6.5e-42 141.3 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 CEP12262.1 - 0.016 14.8 0.0 0.039 13.6 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 CEP12262.1 - 0.022 14.5 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix PadR PF03551.9 CEP12262.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2250 PF10007.4 CEP12262.1 - 0.15 12.0 0.5 12 5.8 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Ribosomal_L16 PF00252.13 CEP12263.1 - 5.6e-34 116.7 0.1 6.7e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.6 CEP12263.1 - 0.15 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Exo_endo_phos PF03372.18 CEP12264.1 - 1.2e-16 61.4 0.1 1.5e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Inhibitor_I78 PF11720.3 CEP12264.1 - 0.0075 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I78 family Arrestin_N PF00339.24 CEP12266.1 - 3.4e-09 36.6 1.5 6.1e-06 26.1 0.3 3.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP12266.1 - 1.1e-08 35.2 9.5 1.1e-05 25.5 0.8 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Polyketide_cyc PF03364.15 CEP12267.1 - 4.8e-09 36.3 0.1 5.5e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Proteasome PF00227.21 CEP12268.1 - 3.9e-58 195.8 1.2 2.3e-57 193.3 0.8 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEP12268.1 - 1.7e-14 52.7 0.0 3.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF605 PF04652.11 CEP12269.1 - 1.1 8.6 34.2 1.6 8.0 23.7 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CEP12269.1 - 8.8 4.4 19.4 10 4.2 13.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HAUS4 PF14735.1 CEP12270.1 - 4.4e-07 29.4 5.1 6.3e-07 28.9 2.3 2.0 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 4 DUF1041 PF06292.12 CEP12270.1 - 0.0036 17.4 1.0 0.0067 16.5 0.7 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PX PF00787.19 CEP12271.1 - 3.7e-20 71.7 0.3 4.7e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 PX domain DUF2100 PF09873.4 CEP12271.1 - 0.057 12.8 0.1 0.072 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) Carb_kinase PF01256.12 CEP12272.1 - 5.8e-49 166.5 0.3 7.7e-49 166.1 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CEP12272.1 - 4.1e-10 39.2 0.2 8e-10 38.3 0.2 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.10 CEP12272.1 - 8.8e-05 21.7 0.3 0.00066 18.9 0.2 2.1 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Hydrolase_3 PF08282.7 CEP12272.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase tRNA_int_endo PF01974.12 CEP12273.1 - 4e-18 64.9 0.0 7.9e-18 64.0 0.0 1.5 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain GATase PF00117.23 CEP12274.1 - 4.4e-36 124.1 0.0 8.5e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 CEP12274.1 - 6.8e-36 121.8 0.1 1.7e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 CEP12274.1 - 1.3e-09 37.3 0.1 3.6e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CEP12274.1 - 1.7e-09 37.4 0.0 3.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 CEP12274.1 - 0.00072 18.9 0.1 0.064 12.5 0.0 2.7 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CEP12274.1 - 0.00087 17.9 0.1 0.002 16.7 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 CEP12274.1 - 0.0026 17.2 0.0 0.0071 15.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 CEP12274.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 CEP12274.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 CEP12274.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PP-loop family HOASN PF14515.1 CEP12274.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices zf-CCHC PF00098.18 CEP12275.1 - 0.0027 17.5 3.2 0.045 13.6 0.1 2.3 2 0 0 2 2 2 2 Zinc knuckle RVT_1 PF00078.22 CEP12277.1 - 2.8e-09 36.6 0.0 6.4e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.8 CEP12279.1 - 3.3 7.4 6.1 4.4 7.0 4.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_3 PF01596.12 CEP12282.1 - 8.4e-39 132.7 0.1 1.4e-38 132.0 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 CEP12282.1 - 5.8e-07 30.0 0.0 2.2e-06 28.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 CEP12282.1 - 1.3e-06 29.1 0.0 8.5e-06 26.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP12282.1 - 0.00012 22.0 0.0 0.00031 20.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CEP12282.1 - 0.00024 20.7 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CEP12282.1 - 0.0021 17.6 0.1 0.0048 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 CEP12282.1 - 0.0024 17.1 0.0 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 Cephalosporin hydroxylase MFS_1 PF07690.11 CEP12283.1 - 5.9e-13 48.2 26.2 2.8e-12 46.0 13.0 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 CEP12284.1 - 2.1e-25 89.5 8.0 2.8e-25 89.1 5.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEP12284.1 - 2.1e-09 37.3 6.5 1e-08 35.0 4.5 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CEP12284.1 - 0.00043 19.0 0.9 0.00099 17.8 0.6 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CEP12284.1 - 0.0061 16.0 0.2 0.0076 15.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CEP12284.1 - 0.067 12.1 0.8 0.1 11.5 0.6 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CEP12284.1 - 0.082 12.9 2.5 0.18 11.8 1.4 1.8 1 1 1 2 2 2 0 NADH(P)-binding HK PF02110.10 CEP12285.1 - 3.7e-80 268.6 5.5 4.7e-80 268.3 3.1 1.6 1 1 1 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CEP12285.1 - 8.5e-62 207.4 1.1 2.7e-61 205.8 0.1 2.0 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 CEP12285.1 - 5.8e-06 25.7 1.8 1e-05 24.9 1.3 1.3 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CEP12285.1 - 0.00033 19.9 0.3 0.00068 18.9 0.2 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CPT PF07931.7 CEP12285.1 - 0.03 13.9 0.1 0.38 10.3 0.0 2.5 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Glu_synthase PF01645.12 CEP12286.1 - 7.8e-157 521.8 0.0 1.2e-156 521.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CEP12286.1 - 5.1e-140 466.2 0.0 8.6e-140 465.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CEP12286.1 - 3.1e-118 394.2 0.0 4.8e-118 393.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 CEP12286.1 - 1.6e-66 223.2 2.5 3e-66 222.3 1.7 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CEP12286.1 - 1.4e-24 85.8 0.2 3.2e-24 84.6 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CEP12286.1 - 1.7e-18 67.2 0.2 5.3e-18 65.6 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP12286.1 - 1.5e-11 44.7 0.1 8.5e-05 22.7 0.1 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP12286.1 - 5.5e-08 32.7 0.0 1.8e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEP12286.1 - 1.2e-07 32.0 0.1 4.7e-05 23.7 0.1 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CEP12286.1 - 7.1e-06 25.3 0.1 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 CEP12286.1 - 3.9e-05 22.3 1.7 4.3e-05 22.1 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 CEP12286.1 - 8.2e-05 21.6 1.5 0.00048 19.1 0.1 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CEP12286.1 - 0.00023 21.3 0.0 0.44 10.8 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CEP12286.1 - 0.00028 19.8 0.4 0.0017 17.3 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CEP12286.1 - 0.00047 19.3 0.1 0.0092 15.1 0.1 2.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 CEP12286.1 - 0.00058 19.0 0.1 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CEP12286.1 - 0.0034 16.3 0.1 0.03 13.1 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 CEP12286.1 - 0.0037 16.8 0.1 0.022 14.3 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 CEP12286.1 - 0.005 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 CEP12286.1 - 0.0068 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GATase_6 PF13522.1 CEP12286.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain DJ-1_PfpI PF01965.19 CEP12286.1 - 0.027 13.9 0.2 0.87 9.0 0.0 2.5 1 1 0 2 2 2 0 DJ-1/PfpI family Shikimate_DH PF01488.15 CEP12286.1 - 0.028 14.5 0.2 9.7 6.2 0.0 3.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 CEP12286.1 - 0.051 11.7 0.3 0.24 9.5 0.0 2.2 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.9 CEP12286.1 - 0.085 12.2 0.4 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IPPT PF01715.12 CEP12287.1 - 2.2e-63 213.6 0.0 3.4e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 CEP12287.1 - 2.7e-05 24.9 0.1 7.6e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CEP12287.1 - 0.0003 20.4 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 CEP12287.1 - 0.00075 19.3 0.0 0.0035 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IPT PF01745.11 CEP12287.1 - 0.0046 16.1 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase RNA_helicase PF00910.17 CEP12287.1 - 0.023 14.8 0.1 0.085 13.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 CEP12287.1 - 0.027 14.7 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CEP12287.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.7 CEP12287.1 - 0.037 13.3 0.1 0.068 12.4 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 CEP12287.1 - 0.048 13.8 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CEP12287.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.18 CEP12287.1 - 0.072 12.4 0.0 0.21 10.9 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 CEP12287.1 - 0.13 11.9 0.1 0.32 10.6 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-C2H2_jaz PF12171.3 CEP12287.1 - 0.27 11.4 2.6 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ABC_tran PF00005.22 CEP12287.1 - 2 8.7 4.8 0.9 9.8 0.5 2.5 2 2 0 2 2 2 0 ABC transporter HSF_DNA-bind PF00447.12 CEP12288.1 - 5.5e-31 106.8 0.1 5.5e-31 106.8 0.1 2.5 3 0 0 3 3 3 1 HSF-type DNA-binding Cse1 PF08506.5 CEP12288.1 - 0.017 13.7 0.1 0.037 12.6 0.1 1.5 1 0 0 1 1 1 0 Cse1 MFS_1 PF07690.11 CEP12289.1 - 1e-35 123.1 16.2 1e-35 123.1 11.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP12289.1 - 3.9e-08 32.3 16.8 3.9e-08 32.3 11.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Rhv PF00073.15 CEP12289.1 - 0.0069 16.0 0.2 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 picornavirus capsid protein SKN1 PF03935.10 CEP12289.1 - 0.14 10.3 0.3 0.26 9.3 0.2 1.4 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) CcmD PF04995.9 CEP12289.1 - 7.9 6.3 7.5 0.36 10.5 0.2 2.6 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) SH3_1 PF00018.23 CEP12290.1 - 1.4e-13 49.9 0.1 2.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP12290.1 - 4.4e-11 42.1 0.1 7.5e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP12290.1 - 2.9e-10 39.4 0.0 5.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CEP12290.1 - 0.0093 16.1 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain TMEMspv1-c74-12 PF11044.3 CEP12290.1 - 5.3 6.6 7.0 1.8 8.1 2.5 1.9 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Copper-fist PF00649.13 CEP12291.1 - 9.9e-16 56.6 4.1 9.9e-16 56.6 2.8 2.0 2 1 0 2 2 2 1 Copper fist DNA binding domain Ribosomal_L36 PF00444.13 CEP12291.1 - 0.3 11.1 8.5 0.074 13.0 3.4 1.8 2 0 0 2 2 2 0 Ribosomal protein L36 CN_hydrolase PF00795.17 CEP12292.1 - 1.1e-25 90.1 0.0 1.8e-25 89.3 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DUF963 PF06131.6 CEP12293.1 - 0.046 13.0 5.7 0.13 11.5 0.7 2.2 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Ferric_reduct PF01794.14 CEP12294.1 - 7.2e-16 58.4 6.3 7.2e-16 58.4 4.4 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CEP12294.1 - 5.9e-09 35.7 0.0 0.0006 19.6 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 CEP12294.1 - 3.9e-08 33.3 0.0 6.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 CEP12294.1 - 0.001 19.5 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEP12294.1 - 0.11 12.6 0.0 7.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Nol1_Nop2_Fmu PF01189.12 CEP12295.1 - 2.5e-28 99.2 0.0 4.5e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CEP12295.1 - 0.00016 21.3 0.5 0.0036 16.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP12295.1 - 0.00091 19.5 0.0 0.0029 17.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP12295.1 - 0.0049 16.0 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 CEP12295.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MIP PF00230.15 CEP12296.1 - 9.6e-50 169.1 10.2 1.2e-49 168.8 7.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein WW PF00397.21 CEP12297.1 - 1.7e-11 43.7 3.4 4.2e-11 42.4 2.4 1.7 1 0 0 1 1 1 1 WW domain ABA_WDS PF02496.11 CEP12297.1 - 0.013 15.6 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 ABA/WDS induced protein PAT1 PF09770.4 CEP12297.1 - 0.8 7.8 31.2 0.95 7.6 21.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CEP12297.1 - 1.5 8.1 22.4 1.8 7.8 15.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF4279 PF14106.1 CEP12298.1 - 0.12 12.2 0.1 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Transglut_i_TM PF14400.1 CEP12298.1 - 0.15 11.5 1.0 0.19 11.2 0.7 1.2 1 0 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices SHS2_FTSA PF02491.15 CEP12298.1 - 0.25 11.2 1.6 1 9.2 0.0 2.2 2 1 0 2 2 2 0 SHS2 domain inserted in FTSA NAM-associated PF14303.1 CEP12298.1 - 0.29 11.4 4.9 0.47 10.7 3.4 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain B2-adapt-app_C PF09066.5 CEP12300.1 - 0.039 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain SAP18 PF06487.7 CEP12300.1 - 0.071 12.9 0.4 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) RNR_inhib PF08591.5 CEP12300.1 - 0.73 10.7 6.4 1 10.2 3.8 1.8 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor WD40 PF00400.27 CEP12301.1 - 4.2e-20 70.8 20.4 0.00056 19.6 0.0 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat CAP_N PF01213.14 CEP12301.1 - 0.3 10.3 3.6 0.54 9.4 2.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 CEP12301.1 - 0.72 9.1 4.8 0.16 11.2 0.5 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator TFIIE_alpha PF02002.12 CEP12302.1 - 5.5e-15 54.7 0.1 1.2e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit B-block_TFIIIC PF04182.7 CEP12302.1 - 0.0035 17.1 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 CEP12302.1 - 0.046 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 MarR family zf-C4_ClpX PF06689.8 CEP12302.1 - 0.054 13.0 0.0 2.7 7.5 0.0 2.9 2 0 0 2 2 2 0 ClpX C4-type zinc finger TF_Zn_Ribbon PF08271.7 CEP12302.1 - 1.7 8.0 6.1 15 5.0 3.8 2.6 1 1 1 2 2 2 0 TFIIB zinc-binding Myb_DNA-binding PF00249.26 CEP12304.1 - 7e-42 141.2 9.5 1.7e-15 56.8 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP12304.1 - 9.9e-40 134.4 8.9 1.3e-17 63.6 0.3 4.0 2 1 2 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 CEP12304.1 - 2.4e-06 27.3 0.3 0.11 12.4 0.2 3.5 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2 PF00096.21 CEP12304.1 - 4.4e-05 23.5 7.1 0.36 11.2 0.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP12304.1 - 0.00078 19.6 4.2 4.7 7.7 0.0 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger Myb_DNA-bind_5 PF13873.1 CEP12304.1 - 1.4 8.8 9.4 12 5.8 0.1 4.4 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain VRR_NUC PF08774.6 CEP12306.1 - 0.0088 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain Plant_tran PF04827.9 CEP12308.1 - 9.8e-25 87.1 0.2 1.9e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 CEP12308.1 - 2.8e-06 27.0 0.0 5.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease NAM-associated PF14303.1 CEP12309.1 - 8.4e-08 32.6 6.4 8.4e-08 32.6 4.4 2.0 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain Myb_DNA-bind_4 PF13837.1 CEP12309.1 - 5e-05 23.3 0.6 5e-05 23.3 0.4 2.4 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Plant_tran PF04827.9 CEP12310.1 - 1.2e-76 256.6 0.1 2e-40 138.3 0.0 3.0 2 1 1 3 3 3 2 Plant transposon protein DDE_Tnp_4 PF13359.1 CEP12310.1 - 6.6e-11 42.0 0.0 1.5e-07 31.1 0.1 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease AsnC_trans_reg PF01037.16 CEP12310.1 - 0.11 12.1 0.0 2.6 7.7 0.0 2.7 1 1 1 2 2 2 0 AsnC family PIF1 PF05970.9 CEP12313.1 - 2.8e-17 62.7 9.5 1.4e-08 34.1 1.6 4.0 1 1 2 3 3 3 3 PIF1-like helicase zf-CCHC PF00098.18 CEP12314.1 - 0.0087 15.9 1.3 0.0087 15.9 0.9 1.8 2 0 0 2 2 2 1 Zinc knuckle Exo_endo_phos_2 PF14529.1 CEP12315.1 - 0.00018 21.0 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP12315.1 - 0.029 14.2 0.1 0.035 14.0 0.1 1.3 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CEP12316.1 - 1.4e-08 34.3 0.0 2.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) REV PF00424.13 CEP12316.1 - 0.049 13.5 0.3 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Tox-URI2 PF15653.1 CEP12318.1 - 0.088 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 URI fold toxin 2 rve PF00665.21 CEP12319.1 - 5.1e-10 39.5 0.0 1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 CEP12320.1 - 7.5e-14 51.8 0.0 2e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CEP12320.1 - 4e-09 36.0 0.8 4e-09 36.0 0.5 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 CEP12322.1 - 6.5e-10 38.9 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP12322.1 - 2.3e-06 27.7 0.0 4.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix DUF402 PF04167.8 CEP12322.1 - 0.019 14.7 0.1 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF402) HTH_28 PF13518.1 CEP12322.1 - 0.02 14.9 0.0 0.077 13.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 CEP12322.1 - 0.072 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain AAA_22 PF13401.1 CEP12324.1 - 0.0011 19.0 0.7 0.0075 16.4 0.0 2.7 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 CEP12324.1 - 0.0018 17.8 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CEP12324.1 - 0.015 15.0 0.8 0.25 11.1 0.5 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 CEP12324.1 - 0.017 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 CEP12324.1 - 0.029 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 CEP12324.1 - 0.11 12.7 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RXT2_N PF08595.6 CEP12325.1 - 0.065 13.0 2.0 0.071 12.9 1.4 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal PIF1 PF05970.9 CEP12326.1 - 1.3e-26 93.4 0.0 1.7e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP12326.1 - 2.2e-05 22.4 0.0 3e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP12326.1 - 0.00012 22.1 0.0 0.00029 20.9 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain FixQ PF05545.6 CEP12327.1 - 1.5 8.4 4.0 0.97 9.1 1.4 1.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Nup_retrotrp_bd PF10599.4 CEP12328.1 - 6.4 7.4 6.7 12 6.5 4.7 1.8 1 1 0 1 1 1 0 Retro-transposon transporting motif CALCOCO1 PF07888.6 CEP12330.1 - 0.16 10.2 2.1 0.21 9.8 1.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_22 PF13401.1 CEP12331.1 - 2.3e-05 24.5 2.3 0.0055 16.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CEP12331.1 - 4.6e-05 23.3 0.2 0.06 13.2 0.0 4.5 4 0 0 4 4 4 1 AAA domain UPF0079 PF02367.12 CEP12331.1 - 0.00033 20.2 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CEP12331.1 - 0.00071 19.4 0.5 0.15 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CEP12331.1 - 0.021 15.0 0.1 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CEP12331.1 - 0.028 14.2 0.2 0.32 10.7 0.1 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit MSP1_C PF07462.6 CEP12331.1 - 3.7 5.8 7.7 5.9 5.1 5.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Exo_endo_phos PF03372.18 CEP12332.1 - 5.4e-09 36.3 0.1 7.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP12332.1 - 0.0076 15.8 0.4 0.34 10.5 0.2 2.6 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase DUF3278 PF11683.3 CEP12334.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF1049 PF06305.6 CEP12334.1 - 4.9 6.7 6.3 4.3 6.9 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) zf-CCHC PF00098.18 CEP12339.1 - 0.00015 21.5 14.4 0.00068 19.4 1.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP12339.1 - 0.61 9.6 17.7 0.077 12.5 6.0 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEP12339.1 - 7.5 6.3 12.4 11 5.7 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle Aminotran_5 PF00266.14 CEP12341.1 - 6.1e-48 163.4 0.0 7.9e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF3991 PF13154.1 CEP12341.1 - 0.12 12.5 0.1 8.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) Caenor_Her-1 PF09232.5 CEP12342.1 - 0.034 14.1 2.3 0.12 12.3 1.0 2.3 1 1 1 2 2 2 0 Caenorhabditis elegans Her-1 Glyco_hydro_18 PF00704.23 CEP12344.1 - 3.9e-17 62.7 0.9 3.5e-15 56.2 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Prok-E2_E PF14462.1 CEP12344.1 - 0.011 15.2 0.2 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E AP_endonuc_2 PF01261.19 CEP12344.1 - 0.07 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF1688 PF07958.6 CEP12345.1 - 5.2e-144 479.8 0.0 9.6e-144 478.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) HA2 PF04408.18 CEP12345.1 - 2.9e-20 72.1 0.0 2.9e-20 72.1 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEP12345.1 - 1.7e-18 66.4 0.0 5.8e-18 64.7 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEP12345.1 - 7.7e-13 48.1 0.0 2.7e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP12345.1 - 2.4e-08 33.6 0.2 6.4e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEP12345.1 - 6.7e-07 29.5 0.2 4.6e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CEP12345.1 - 0.0022 16.9 0.0 0.0041 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 CEP12345.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 CEP12345.1 - 0.012 15.4 0.0 0.044 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CEP12345.1 - 0.02 14.7 1.1 0.66 9.7 0.0 3.0 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 CEP12345.1 - 0.022 14.2 0.0 0.078 12.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family FAR1 PF03101.10 CEP12346.1 - 0.047 14.2 0.6 0.088 13.3 0.4 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain RRM_6 PF14259.1 CEP12347.1 - 0.0011 18.8 0.4 0.0067 16.3 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12347.1 - 0.0024 17.7 0.1 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP12347.1 - 0.04 13.5 0.0 0.72 9.5 0.0 2.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FUSC-like PF12805.2 CEP12347.1 - 6.3 5.6 8.3 10 4.9 5.7 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Rhomboid PF01694.17 CEP12348.1 - 1.2e-19 70.8 8.9 2.2e-19 69.9 6.1 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 CEP12348.1 - 0.015 15.5 0.0 0.044 14.1 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) TP2 PF01254.13 CEP12349.1 - 0.16 12.3 9.8 0.32 11.3 6.8 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 Glyco_hydro_81 PF03639.8 CEP12350.1 - 3.7e-111 372.2 0.6 2.6e-110 369.5 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 Methyltransf_11 PF08241.7 CEP12351.1 - 1e-13 51.5 0.0 2.9e-13 50.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP12351.1 - 2.9e-12 46.6 0.0 7.3e-12 45.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP12351.1 - 5.3e-10 39.0 0.0 9.1e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP12351.1 - 2.2e-07 31.2 0.1 5.9e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP12351.1 - 2.5e-06 26.7 0.2 3.7e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEP12351.1 - 5.9e-06 26.5 0.0 4.7e-05 23.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 CEP12351.1 - 0.0027 17.1 0.1 0.0048 16.3 0.1 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEP12351.1 - 0.0061 17.1 0.1 0.024 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP12351.1 - 0.0074 16.3 0.0 0.027 14.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CEP12351.1 - 0.019 14.3 0.4 0.044 13.1 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain DREV PF05219.7 CEP12351.1 - 0.034 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_PK PF05891.7 CEP12351.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Exo_endo_phos PF03372.18 CEP12352.1 - 0.028 14.3 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Snapin_Pallidin PF14712.1 CEP12352.1 - 0.079 13.2 1.8 0.15 12.3 1.2 1.5 1 0 0 1 1 1 0 Snapin/Pallidin FlxA PF14282.1 CEP12352.1 - 4.3 7.3 9.9 0.13 12.2 2.1 1.8 2 0 0 2 2 2 0 FlxA-like protein RVT_1 PF00078.22 CEP12353.1 - 1.3e-10 41.0 0.3 2e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pex14_N PF04695.8 CEP12355.1 - 1.1 9.3 3.4 1.4 8.9 2.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SAM_2 PF07647.12 CEP12356.1 - 1.6e-08 34.2 0.3 4.8e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEP12356.1 - 8e-07 29.1 0.5 4.9e-06 26.6 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase PF00069.20 CEP12357.1 - 1.2e-50 172.0 0.2 4.3e-50 170.2 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CEP12357.1 - 3.3e-50 166.2 15.8 2.9e-10 39.6 0.0 8.4 7 2 0 7 7 7 7 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 CEP12357.1 - 8e-21 74.2 0.0 2.1e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase F-box-like PF12937.2 CEP12357.1 - 1.6e-08 34.0 0.2 3.3e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP12357.1 - 2.4e-08 33.4 0.1 5e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain APH PF01636.18 CEP12357.1 - 1.7e-06 27.9 0.1 0.00041 20.1 0.2 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Nup160 PF11715.3 CEP12357.1 - 7e-05 21.1 4.1 0.41 8.7 0.0 3.8 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Choline_kinase PF01633.15 CEP12357.1 - 0.0052 16.3 0.2 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CEP12357.1 - 0.037 13.3 0.1 6.7 5.9 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PQQ_2 PF13360.1 CEP12357.1 - 0.05 13.0 0.2 1.8 8.0 0.1 2.9 1 1 0 1 1 1 0 PQQ-like domain PRANC PF09372.5 CEP12357.1 - 0.34 10.8 4.7 0.27 11.2 0.2 2.9 2 1 0 2 2 2 0 PRANC domain zf-C2H2_4 PF13894.1 CEP12361.1 - 0.33 11.3 2.1 0.67 10.4 1.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger GCR1_C PF12550.3 CEP12362.1 - 2.5e-05 24.0 0.2 5.6e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes GTP_EFTU PF00009.22 CEP12363.1 - 1.6e-19 70.1 0.0 2.8e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CEP12363.1 - 0.0011 19.2 0.1 0.0079 16.4 0.0 2.2 1 1 1 2 2 2 1 ABC transporter cobW PF02492.14 CEP12363.1 - 0.006 16.0 0.2 0.11 11.9 0.2 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CEP12363.1 - 0.01 15.7 0.0 0.031 14.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CEP12363.1 - 0.013 15.1 0.6 0.54 9.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 CEP12363.1 - 0.016 14.3 0.1 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CEP12363.1 - 0.023 14.1 0.2 13 5.3 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 CEP12363.1 - 0.041 13.8 0.1 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU_D3 PF03143.12 CEP12363.1 - 0.047 13.8 0.0 0.36 11.0 0.0 2.3 1 1 0 1 1 1 0 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEP12363.1 - 0.058 13.5 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Arf PF00025.16 CEP12363.1 - 0.093 11.9 0.1 4.2 6.5 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3759 PF12585.3 CEP12364.1 - 1.2e-14 53.9 7.7 2.9e-14 52.7 5.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Ricin_B_lectin PF00652.17 CEP12364.1 - 2.1e-07 31.0 0.0 0.0069 16.4 0.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP12364.1 - 2.3e-06 27.9 0.1 0.032 14.6 0.0 3.1 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like SMC_N PF02463.14 CEP12365.1 - 1.2e-67 227.3 1.8 3e-67 226.0 1.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CEP12365.1 - 4.5e-29 100.8 0.3 1.4e-27 95.9 0.0 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CEP12365.1 - 8.6e-14 52.3 30.5 8.6e-14 52.3 21.1 6.5 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 CEP12365.1 - 4.3e-11 43.3 24.9 9.9e-08 32.2 2.6 3.7 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CEP12365.1 - 0.00072 19.0 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CEP12365.1 - 0.11 11.9 0.0 0.11 11.9 0.0 3.5 4 1 0 4 4 4 0 FtsK/SpoIIIE family ThiS PF02597.15 CEP12365.1 - 0.92 9.9 7.1 1.1 9.6 0.0 4.1 3 0 0 3 3 3 0 ThiS family Septin PF00735.13 CEP12366.1 - 2e-17 63.1 2.3 2.7e-17 62.7 0.0 2.3 2 1 0 2 2 2 1 Septin Miro PF08477.8 CEP12366.1 - 3.4e-05 24.3 0.7 0.00024 21.5 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein DUF258 PF03193.11 CEP12366.1 - 9.3e-05 21.6 0.0 0.00021 20.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CEP12366.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CEP12366.1 - 0.0085 16.0 0.2 0.078 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CEP12366.1 - 0.011 15.3 0.8 0.032 13.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 CEP12366.1 - 0.027 14.6 1.6 0.063 13.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.12 CEP12366.1 - 0.04 13.3 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 CEP12366.1 - 0.09 12.9 4.0 1.2 9.3 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rdx PF10262.4 CEP12367.1 - 1.9e-28 98.2 0.0 2.6e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Rdx family TPR_12 PF13424.1 CEP12368.1 - 2.7e-20 72.0 4.7 2.9e-08 33.5 0.2 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CEP12368.1 - 1.1e-14 53.8 4.7 3.8e-06 26.4 0.3 4.4 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 CEP12368.1 - 5.3e-14 51.1 9.0 0.082 12.5 1.7 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12368.1 - 2.5e-13 48.8 11.0 0.11 12.4 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CEP12368.1 - 5.2e-08 32.1 8.0 0.28 11.0 0.7 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP12368.1 - 1.8e-06 28.0 6.7 2.7 8.8 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP12368.1 - 2.2e-05 23.9 4.3 8.3 6.4 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP12368.1 - 3.2e-05 23.6 8.2 0.019 14.8 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP12368.1 - 3.9e-05 24.2 3.8 0.52 11.0 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP12368.1 - 0.0031 17.8 4.7 0.59 10.5 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP12368.1 - 0.0077 16.3 1.2 0.32 11.3 0.2 3.8 4 1 0 4 4 3 1 Tetratricopeptide repeat Sel1 PF08238.7 CEP12368.1 - 0.022 15.3 2.6 29 5.4 0.0 4.7 4 1 0 4 4 4 0 Sel1 repeat DUF3094 PF11293.3 CEP12368.1 - 0.039 13.4 0.1 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) TPR_5 PF12688.2 CEP12368.1 - 0.099 12.6 0.6 5.9 6.9 0.0 3.2 3 1 0 3 3 3 0 Tetratrico peptide repeat SPO22 PF08631.5 CEP12368.1 - 0.14 11.2 0.8 8.2 5.4 0.1 2.9 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like PPR_2 PF13041.1 CEP12368.1 - 0.14 12.1 0.2 78 3.3 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family TPR_6 PF13174.1 CEP12368.1 - 0.29 11.6 9.0 30 5.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat OPT PF03169.10 CEP12370.1 - 3.2e-93 313.2 35.3 3.6e-93 313.0 24.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 CEP12370.1 - 0.014 15.2 0.2 0.043 13.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) IncFII_repA PF02387.10 CEP12370.1 - 0.39 9.8 0.1 0.62 9.1 0.1 1.3 1 0 0 1 1 1 0 IncFII RepA protein family SPC25 PF06703.6 CEP12371.1 - 5.1e-38 130.1 1.1 6e-38 129.9 0.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4401 PF14351.1 CEP12371.1 - 0.05 12.6 0.0 0.066 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Pyr_redox_2 PF07992.9 CEP12372.1 - 3.9e-40 137.8 0.0 1.2e-39 136.2 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CEP12372.1 - 1.8e-33 114.8 2.3 2.2e-32 111.3 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CEP12372.1 - 2e-19 69.7 0.2 2e-19 69.7 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP12372.1 - 2.6e-10 40.7 3.2 3e-07 30.7 0.4 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP12372.1 - 8.4e-07 28.4 0.9 2e-06 27.1 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 CEP12372.1 - 1.2e-05 24.5 0.1 0.00024 20.3 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CEP12372.1 - 4e-05 23.0 0.1 7.4e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 CEP12372.1 - 4.1e-05 22.2 12.5 0.083 11.3 0.1 3.5 3 1 1 4 4 4 3 HI0933-like protein 3HCDH_N PF02737.13 CEP12372.1 - 6.4e-05 22.6 0.3 6.4e-05 22.6 0.2 2.5 2 1 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 CEP12372.1 - 0.0002 20.4 13.5 0.021 13.7 1.7 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CEP12372.1 - 0.00035 20.1 1.6 0.00091 18.8 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 CEP12372.1 - 0.00058 18.8 0.1 0.011 14.6 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEP12372.1 - 0.0028 17.6 2.2 0.0028 17.6 1.5 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEP12372.1 - 0.0044 15.9 12.8 0.038 12.8 4.5 3.1 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.17 CEP12372.1 - 0.0074 15.1 4.4 0.097 11.5 1.5 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 CEP12372.1 - 0.03 14.0 0.0 0.03 14.0 0.0 2.4 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CEP12372.1 - 0.29 11.5 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CEP12372.1 - 0.31 11.3 2.2 0.68 10.2 0.1 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1027 PF06265.6 CEP12372.1 - 0.33 10.8 1.5 5.9 6.8 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1027) Thi4 PF01946.12 CEP12372.1 - 0.58 9.2 12.5 0.16 11.0 4.6 3.1 3 1 0 3 3 3 0 Thi4 family FAA_hydrolase PF01557.13 CEP12373.1 - 4.6e-53 179.9 0.0 5.9e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HMG_box PF00505.14 CEP12374.1 - 1.5e-34 118.0 12.7 1.8e-15 56.9 0.0 4.5 4 1 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP12374.1 - 4.7e-31 106.9 8.6 1.6e-13 50.7 0.4 4.5 4 0 0 4 4 4 3 HMG-box domain Methyltransf_16 PF10294.4 CEP12375.1 - 3.8e-34 117.6 0.0 7.7e-34 116.6 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEP12375.1 - 3.6e-06 27.5 0.0 5.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP12375.1 - 0.0012 18.5 0.1 0.0037 16.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP12375.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP12375.1 - 0.033 13.8 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEP12375.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.1 CEP12375.1 - 0.055 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CEP12375.1 - 0.063 13.7 0.7 0.11 12.9 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain TRM PF02005.11 CEP12375.1 - 0.09 11.6 0.0 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_32 PF13679.1 CEP12375.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain cNMP_binding PF00027.24 CEP12376.1 - 1.5e-42 143.2 0.3 5.1e-20 71.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CEP12376.1 - 2.7e-08 33.0 1.7 5.7e-08 32.0 1.2 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit FRD2 PF03197.8 CEP12376.1 - 0.0016 18.9 3.1 0.16 12.5 0.2 2.5 2 0 0 2 2 2 2 Bacteriophage FRD2 protein Dpy-30 PF05186.8 CEP12376.1 - 0.019 14.4 0.1 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Dpy-30 motif Septin PF00735.13 CEP12377.1 - 4.5e-111 370.3 0.3 7.9e-111 369.5 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEP12377.1 - 9.6e-08 31.9 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP12377.1 - 1.8e-07 30.8 0.2 8.7e-06 25.2 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEP12377.1 - 4.8e-07 29.0 0.1 1.4e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CEP12377.1 - 0.00018 21.9 1.0 0.00036 21.0 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CEP12377.1 - 0.00065 19.8 0.1 0.0029 17.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CEP12377.1 - 0.00087 18.8 0.9 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Ras PF00071.17 CEP12377.1 - 0.0046 16.3 0.2 0.013 14.8 0.1 1.8 1 1 0 1 1 1 1 Ras family RNA_helicase PF00910.17 CEP12377.1 - 0.0057 16.8 0.0 0.022 14.9 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AIG1 PF04548.11 CEP12377.1 - 0.006 15.7 0.1 0.017 14.2 0.1 1.8 1 0 0 1 1 1 1 AIG1 family Sigma54_activat PF00158.21 CEP12377.1 - 0.0077 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 CEP12377.1 - 0.0081 16.1 0.2 0.076 13.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 CEP12377.1 - 0.014 15.2 0.4 0.035 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CEP12377.1 - 0.021 14.3 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 CEP12377.1 - 0.027 14.0 0.1 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 CEP12377.1 - 0.054 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein Dynamin_N PF00350.18 CEP12377.1 - 0.066 13.0 10.3 0.48 10.2 0.0 3.4 2 2 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 CEP12377.1 - 0.068 12.6 0.9 1 8.8 0.1 2.9 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CEP12377.1 - 0.069 12.6 0.4 2.9 7.3 0.3 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CEP12377.1 - 0.088 12.5 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CEP12377.1 - 0.093 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CEP12377.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CEP12377.1 - 0.11 12.7 0.0 0.11 12.7 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Lge1 PF11488.3 CEP12377.1 - 0.57 10.4 0.0 0.57 10.4 0.0 3.0 2 1 0 2 2 1 0 Transcriptional regulatory protein LGE1 APG6 PF04111.7 CEP12377.1 - 1.5 7.7 12.7 2.7 6.9 8.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C3HC4_3 PF13920.1 CEP12378.1 - 0.0065 16.1 18.5 0.033 13.8 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Snapin_Pallidin PF14712.1 CEP12378.1 - 0.036 14.3 6.1 0.049 13.9 3.6 1.7 1 1 0 1 1 1 0 Snapin/Pallidin Spc24 PF08286.6 CEP12378.1 - 0.057 13.1 9.3 0.15 11.7 6.4 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 HALZ PF02183.13 CEP12378.1 - 0.073 12.7 15.9 0.17 11.6 1.4 3.7 3 1 1 4 4 4 0 Homeobox associated leucine zipper ATG16 PF08614.6 CEP12378.1 - 0.15 11.9 12.2 0.12 12.1 6.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 CEP12378.1 - 0.18 11.7 14.6 0.2 11.5 6.4 2.4 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 CEP12378.1 - 0.3 10.2 5.1 0.51 9.4 3.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein VEK-30 PF12107.3 CEP12378.1 - 1 9.1 3.2 2.1 8.1 0.9 2.5 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway DUF342 PF03961.8 CEP12378.1 - 1.9 6.8 6.5 2.9 6.2 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 CEP12378.1 - 2.9 7.4 10.7 0.41 10.1 0.4 3.1 1 1 2 3 3 3 0 Septum formation initiator Striatin PF08232.7 CEP12378.1 - 3.7 7.8 18.5 2.6 8.3 3.2 3.2 3 0 0 3 3 3 0 Striatin family DUF904 PF06005.7 CEP12378.1 - 4.7 7.5 20.7 31 4.9 8.3 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 CEP12378.1 - 7 6.6 9.2 1.9 8.4 0.3 3.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) PSS PF03034.10 CEP12379.1 - 5.8e-103 344.1 15.6 5.8e-103 344.1 10.8 1.6 2 0 0 2 2 2 1 Phosphatidyl serine synthase DUF4233 PF14017.1 CEP12379.1 - 3.9 7.4 11.0 0.25 11.2 1.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4233) SAC3_GANP PF03399.11 CEP12380.1 - 1.4e-54 184.7 0.8 2.5e-54 183.9 0.6 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Ribosomal_S26e PF01283.14 CEP12381.1 - 1.1e-51 173.8 8.4 1.2e-51 173.7 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_10 PF13237.1 CEP12381.1 - 0.13 12.0 3.3 0.57 10.0 2.0 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 CEP12381.1 - 0.4 10.7 3.0 1.2 9.2 2.1 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF2839 PF10999.3 CEP12382.1 - 0.058 13.4 1.2 0.14 12.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) YukC PF10140.4 CEP12382.1 - 0.12 10.8 1.8 0.16 10.5 1.3 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Sof1 PF04158.9 CEP12382.1 - 0.19 11.8 3.5 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Sof1-like domain PAT1 PF09770.4 CEP12383.1 - 0.082 11.1 6.4 0.097 10.8 4.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Shisa PF13908.1 CEP12383.1 - 4.2 7.5 6.5 5.6 7.1 4.5 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator NAD_binding_1 PF00175.16 CEP12384.1 - 0.075 13.6 1.2 0.57 10.7 0.1 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain PIF1 PF05970.9 CEP12386.1 - 6e-40 137.3 0.0 8.5e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP12386.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP12386.1 - 0.00036 20.2 0.4 0.00069 19.3 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CEP12386.1 - 0.0051 16.8 0.2 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CEP12386.1 - 0.007 16.5 0.2 0.043 13.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CEP12386.1 - 0.019 13.6 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 CEP12386.1 - 0.029 13.3 0.1 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 CEP12386.1 - 0.085 11.8 0.0 0.16 10.9 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain AAA_11 PF13086.1 CEP12386.1 - 0.087 12.3 0.0 0.24 10.9 0.0 1.6 1 1 0 2 2 2 0 AAA domain RE_HpaII PF09561.5 CEP12386.1 - 0.093 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 HpaII restriction endonuclease IstB_IS21 PF01695.12 CEP12386.1 - 0.1 12.0 0.3 0.76 9.1 0.0 2.3 2 1 1 3 3 3 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CEP12386.1 - 0.13 11.7 0.3 0.28 10.6 0.0 1.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CEP12386.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 CEP12386.1 - 0.14 11.2 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Peptidase_M1 PF01433.15 CEP12387.1 - 2.8e-77 260.4 0.0 3.6e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CEP12387.1 - 1.6e-44 150.9 0.9 2.5e-44 150.3 0.1 1.7 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CEP12387.1 - 1.2e-14 54.4 0.0 2.3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily FlaC_arch PF05377.6 CEP12388.1 - 3.2e-05 23.7 1.3 3.2e-05 23.7 0.9 2.2 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) DUF632 PF04782.7 CEP12388.1 - 0.0069 15.5 1.0 0.013 14.6 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF632) Baculo_PEP_C PF04513.7 CEP12388.1 - 0.016 15.0 0.8 0.032 14.0 0.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CEP12388.1 - 0.074 13.3 0.7 0.64 10.3 0.3 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 CEP12388.1 - 0.084 13.0 1.8 0.17 12.0 0.6 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 CEP12388.1 - 0.1 11.7 2.7 0.095 11.8 1.1 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Filo_VP35 PF02097.10 CEP12388.1 - 0.11 11.7 0.4 0.16 11.1 0.3 1.2 1 0 0 1 1 1 0 Filoviridae VP35 DUF4460 PF14687.1 CEP12388.1 - 0.16 11.7 1.3 5.2 6.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) Laminin_II PF06009.7 CEP12388.1 - 0.16 11.6 3.3 0.47 10.2 1.0 2.3 2 1 0 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.15 CEP12388.1 - 0.33 10.7 3.6 0.22 11.3 0.2 2.4 3 0 0 3 3 3 0 Prefoldin subunit Syntaxin PF00804.20 CEP12388.1 - 3.6 7.7 6.9 26 5.0 3.8 3.0 1 1 1 2 2 2 0 Syntaxin zf-C3HC4 PF00097.20 CEP12390.1 - 7.8e-11 41.4 7.9 1.3e-10 40.7 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP12390.1 - 1.4e-10 41.0 9.0 2.5e-10 40.1 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP12390.1 - 4.2e-10 39.2 9.5 4.2e-10 39.2 6.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CEP12390.1 - 1.4e-08 34.2 6.9 2.5e-08 33.4 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP12390.1 - 9.6e-08 31.5 7.9 1.7e-07 30.8 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP12390.1 - 3e-06 26.8 4.0 5.7e-06 25.9 0.8 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CEP12390.1 - 7e-06 25.8 8.3 1.2e-05 25.0 5.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 CEP12390.1 - 1.2e-05 25.0 4.5 1.9e-05 24.4 3.1 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-Apc11 PF12861.2 CEP12390.1 - 7.4e-05 22.5 3.4 0.00099 18.9 3.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CEP12390.1 - 0.00092 19.2 8.6 0.0034 17.4 5.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 CEP12390.1 - 0.14 11.7 7.2 0.23 11.0 5.0 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Rtf2 PF04641.7 CEP12390.1 - 0.23 10.6 0.1 0.23 10.6 0.1 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_6 PF14835.1 CEP12390.1 - 0.35 10.6 4.8 0.66 9.8 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CEP12390.1 - 0.73 9.4 7.6 0.085 12.4 1.7 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.16 CEP12390.1 - 2.9 7.8 9.8 20 5.1 6.9 2.2 1 1 0 1 1 1 0 IBR domain Usp PF00582.21 CEP12391.1 - 6.9e-13 48.9 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family AMP-binding PF00501.23 CEP12392.1 - 1.7e-96 323.2 0.1 2.1e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP12392.1 - 1.4e-18 67.5 0.1 3.4e-18 66.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RhoGEF PF00621.15 CEP12393.1 - 4.8e-49 166.6 3.4 4.8e-49 166.6 2.3 3.0 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.23 CEP12393.1 - 3.7e-20 71.0 2.4 1.5e-09 37.0 0.5 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CEP12393.1 - 6.2e-17 60.9 3.3 2.3e-07 30.2 0.4 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 CEP12393.1 - 9.7e-16 57.0 0.1 2.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain DUF239 PF03080.10 CEP12393.1 - 0.00018 20.6 0.7 0.004 16.2 0.1 2.6 1 1 0 2 2 2 1 Domain of unknown function (DUF239) DUF3712 PF12505.3 CEP12394.1 - 8.7e-65 216.4 48.1 3.5e-22 78.7 1.4 6.9 8 0 0 8 8 8 4 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CEP12394.1 - 1.1e-14 54.5 11.4 0.0045 17.3 0.0 8.1 8 0 0 8 8 8 5 Late embryogenesis abundant protein Med13_N PF11597.3 CEP12394.1 - 0.28 9.8 4.1 0.49 9.0 2.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal SLD3 PF08639.5 CEP12394.1 - 4.9 5.6 10.4 7.5 5.0 7.2 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 UFD1 PF03152.9 CEP12395.1 - 1.9e-75 251.8 0.0 2.4e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PsiA PF06952.6 CEP12397.1 - 0.032 13.3 1.4 0.046 12.7 1.0 1.2 1 0 0 1 1 1 0 PsiA protein PX PF00787.19 CEP12398.1 - 5.9e-19 67.9 0.0 1.4e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 PX domain Gal4_dimer PF03902.8 CEP12398.1 - 0.044 13.7 0.4 1.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Gal4-like dimerisation domain RAMPs PF03787.10 CEP12398.1 - 0.063 13.1 0.2 0.25 11.1 0.1 2.0 1 1 0 1 1 1 0 RAMP superfamily RRM_1 PF00076.17 CEP12399.1 - 4.8e-10 38.9 0.0 8.2e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12399.1 - 4.4e-09 36.2 0.0 8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12399.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP160 PF07918.6 CEP12399.1 - 0.11 12.1 0.6 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 CAP160 repeat Pkinase PF00069.20 CEP12401.1 - 1.1e-36 126.3 0.6 3.3e-36 124.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12401.1 - 3e-12 46.1 0.0 4.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CEP12401.1 - 0.031 13.6 1.3 0.064 12.5 0.0 2.2 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL APH PF01636.18 CEP12401.1 - 0.066 12.9 0.0 0.57 9.8 0.0 2.3 2 1 0 3 3 3 0 Phosphotransferase enzyme family ubiquitin PF00240.18 CEP12402.1 - 3.4e-28 96.8 1.8 1.1e-14 53.5 0.2 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CEP12402.1 - 1.7e-14 53.2 0.8 1.6e-08 34.0 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEP12402.1 - 2.2e-05 24.6 2.2 0.015 15.5 0.0 2.8 1 1 1 2 2 2 2 Ubiquitin-like domain USP7_C2 PF14533.1 CEP12402.1 - 8.5e-05 22.0 0.4 0.0044 16.4 0.0 2.2 1 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal GABP-alpha PF11620.3 CEP12402.1 - 0.00028 20.8 1.7 0.19 11.7 0.1 2.2 1 1 1 2 2 2 2 GA-binding protein alpha chain YukD PF08817.5 CEP12402.1 - 0.00043 20.7 0.0 0.00081 19.9 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD UN_NPL4 PF11543.3 CEP12402.1 - 0.063 13.5 0.1 5.3 7.3 0.0 2.4 2 1 0 2 2 2 0 Nuclear pore localisation protein NPL4 CLU_N PF15044.1 CEP12402.1 - 0.15 12.2 0.6 25 5.1 0.0 2.9 2 2 0 2 2 2 0 Mitochondrial function, CLU-N-term Arrestin_C PF02752.17 CEP12403.1 - 2e-10 40.9 0.8 1.4e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP12403.1 - 2.2e-06 27.5 0.0 1.9e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyco_transf_22 PF03901.12 CEP12404.1 - 1.3e-35 123.1 29.7 1.7e-35 122.8 20.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glutaredoxin PF00462.19 CEP12404.1 - 1.3e-15 57.0 0.1 2.9e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 CEP12404.1 - 0.018 15.2 0.1 0.048 13.9 0.1 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 CEP12404.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Abhydrolase_3 PF07859.8 CEP12405.1 - 5.3e-33 114.3 0.0 1.7e-22 80.0 0.0 3.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CEP12405.1 - 0.0021 16.7 0.0 0.0037 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Glyoxalase_4 PF13669.1 CEP12405.1 - 0.16 11.9 0.0 0.66 10.0 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Med1 PF10744.4 CEP12406.1 - 1e-13 50.8 6.0 3.5e-08 32.6 1.0 3.1 1 1 1 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 F-box-like PF12937.2 CEP12407.1 - 7.1e-05 22.4 0.2 0.00022 20.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like Homez PF11569.3 CEP12407.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez F-box PF00646.28 CEP12407.1 - 0.076 12.6 0.3 0.22 11.2 0.2 1.8 1 0 0 1 1 1 0 F-box domain Hydrolase PF00702.21 CEP12408.1 - 1.7e-23 84.1 0.0 9.4e-23 81.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEP12408.1 - 3.1e-23 82.0 0.0 9.5e-23 80.4 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CEP12408.1 - 6.5e-22 78.6 0.0 1.3e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-MYND PF01753.13 CEP12408.1 - 0.00015 21.5 15.4 0.00034 20.4 10.7 1.6 1 0 0 1 1 1 1 MYND finger Hydrolase_like2 PF13246.1 CEP12408.1 - 0.0026 17.6 0.0 0.0071 16.2 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit SET PF00856.23 CEP12408.1 - 0.0054 17.0 0.0 0.021 15.1 0.0 2.1 1 1 0 1 1 1 1 SET domain Hydrolase_3 PF08282.7 CEP12408.1 - 0.023 14.2 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Tmemb_9 PF05434.6 CEP12409.1 - 0.0063 16.2 0.8 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 TMEM9 LRR19-TM PF15176.1 CEP12409.1 - 0.13 11.9 1.9 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain 7TM_GPCR_Srv PF10323.4 CEP12409.1 - 0.27 10.3 7.3 0.49 9.4 1.3 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Yip1 PF04893.12 CEP12409.1 - 0.35 10.3 6.3 0.84 9.1 4.4 1.6 1 1 0 1 1 1 0 Yip1 domain Baculo_11_kDa PF06143.6 CEP12409.1 - 0.41 10.0 3.0 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family Kei1 PF08552.6 CEP12409.1 - 0.47 10.0 7.4 0.045 13.4 0.6 2.0 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 MARVEL PF01284.18 CEP12409.1 - 4.3 7.1 12.6 16 5.3 7.8 2.0 1 1 0 1 1 1 0 Membrane-associating domain Retrotrans_gag PF03732.12 CEP12410.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein FWWh PF14922.1 CEP12410.1 - 0.072 12.5 0.1 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function rve PF00665.21 CEP12411.1 - 2.4e-18 66.3 0.0 5.9e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP12411.1 - 9.3e-09 34.9 1.4 3.8e-08 32.9 0.9 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CEP12411.1 - 2e-07 30.5 0.2 4.8e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4286 PF14114.1 CEP12411.1 - 0.042 14.1 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Mtf2_C PF14061.1 CEP12411.1 - 0.071 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DDE_3 PF13358.1 CEP12412.1 - 3.2e-29 101.5 0.0 5e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP12412.1 - 7.1e-07 29.9 0.0 5.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP12412.1 - 8.2e-07 29.1 0.0 2.7e-06 27.5 0.0 1.9 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 CEP12412.1 - 9.2e-06 25.1 0.1 9.7e-05 21.8 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP12412.1 - 2.8e-05 24.0 0.1 0.00032 20.6 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 CEP12412.1 - 0.0016 18.3 0.3 0.0037 17.1 0.0 1.7 2 0 0 2 2 2 1 Transposase rve PF00665.21 CEP12412.1 - 0.024 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DDE_1 PF03184.14 CEP12412.1 - 0.028 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 CEP12412.1 - 0.043 12.9 0.1 0.36 10.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 zf-C4pol PF14260.1 CEP12413.1 - 0.0085 16.0 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF1287 PF06940.6 CEP12413.1 - 0.063 12.6 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) zf-CCHC_5 PF14787.1 CEP12413.1 - 0.068 12.6 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.12 CEP12414.1 - 4.6e-06 26.6 0.0 5e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Retrotransposon gag protein Ribosomal_S5_C PF03719.10 CEP12414.1 - 0.13 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain RTP PF02334.11 CEP12416.1 - 0.088 12.7 1.1 0.12 12.3 0.8 1.2 1 0 0 1 1 1 0 Replication terminator protein Mucin PF01456.12 CEP12417.1 - 0.01 15.5 12.1 0.01 15.5 8.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein UDG PF03167.14 CEP12418.1 - 1.5e-26 92.7 0.0 2.1e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SMC_N PF02463.14 CEP12419.1 - 2.2e-64 216.6 20.5 2e-35 122.0 5.2 3.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CEP12419.1 - 7e-20 71.1 0.2 3.5e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CEP12419.1 - 1.9e-14 54.4 14.8 1.9e-14 54.4 10.2 6.3 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 CEP12419.1 - 2.5e-09 37.5 13.2 7.6e-06 26.0 0.1 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CEP12419.1 - 0.00029 20.2 0.0 0.00074 19.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CEP12419.1 - 1 8.4 39.8 1.1 8.4 1.2 6.1 2 2 4 6 6 6 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CEP12419.1 - 4.3 5.6 98.2 0.0033 15.9 14.8 6.3 4 2 3 7 7 7 0 AAA domain Phage_coat PF09063.5 CEP12420.1 - 0.05 13.4 0.1 0.077 12.7 0.1 1.2 1 0 0 1 1 1 0 Phage PP7 coat protein CagE_TrbE_VirB PF03135.9 CEP12420.1 - 0.1 12.3 1.2 0.14 11.9 0.8 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF4653 PF15546.1 CEP12420.1 - 4.7 6.4 7.3 0.85 8.8 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) POM121 PF15229.1 CEP12423.1 - 0.02 14.3 1.2 0.021 14.2 0.8 1.1 1 0 0 1 1 1 0 POM121 family AT_hook PF02178.14 CEP12423.1 - 0.16 11.7 2.6 0.35 10.6 1.8 1.6 1 0 0 1 1 1 0 AT hook motif THRAP3_BCLAF1 PF15440.1 CEP12424.1 - 0.076 11.6 4.6 0.098 11.3 3.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Transposase_21 PF02992.9 CEP12426.1 - 7.9e-06 25.1 0.0 9.7e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Exo_endo_phos PF03372.18 CEP12429.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CEP12431.1 - 6.4e-07 29.6 0.8 2.9e-06 27.5 0.2 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase ComJ PF11033.3 CEP12432.1 - 0.045 13.3 0.2 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 Competence protein J (ComJ) RVT_1 PF00078.22 CEP12433.1 - 3.7e-27 95.0 0.1 9.6e-27 93.7 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP12433.1 - 4.3e-09 35.9 0.1 2e-08 33.8 0.1 2.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP12433.1 - 3.6e-06 27.1 0.1 9.6e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SLEI_Leptospira PF07620.6 CEP12434.1 - 0.048 13.4 0.2 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 SLEI SR-25 PF10500.4 CEP12434.1 - 0.68 9.3 8.7 0.82 9.1 6.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCCH PF00642.19 CEP12435.1 - 4.5e-08 32.5 0.7 4.5e-08 32.5 0.5 2.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pox_A14 PF05767.7 CEP12436.1 - 0.072 13.0 2.7 4 7.4 0.3 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 IspA PF04279.10 CEP12436.1 - 0.3 11.0 16.7 4.4 7.2 11.6 2.4 1 1 0 1 1 1 0 Intracellular septation protein A MerC PF03203.9 CEP12436.1 - 1.2 9.5 10.9 12 6.3 7.6 2.4 1 1 0 1 1 1 0 MerC mercury resistance protein DUF3159 PF11361.3 CEP12436.1 - 1.7 8.0 13.6 7.3 6.0 9.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3159) CPSF73-100_C PF11718.3 CEP12437.1 - 2.7e-56 190.3 0.2 4.8e-56 189.5 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CEP12437.1 - 4.4e-34 117.1 0.0 1.3e-33 115.6 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 CEP12437.1 - 1.4e-10 40.7 0.1 3.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CEP12437.1 - 1.7e-05 24.4 0.3 6.3e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEP12437.1 - 0.0014 18.2 0.6 0.0033 17.1 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 CEP12437.1 - 0.0051 16.5 0.1 0.016 14.9 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SR-25 PF10500.4 CEP12438.1 - 2.4 7.5 7.9 4.1 6.7 5.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IF4E PF01652.13 CEP12439.1 - 2.8e-25 88.7 0.0 6.4e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Gag_p15 PF08723.5 CEP12439.1 - 0.043 13.8 0.1 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Gag protein p15 DUF2423 PF10338.4 CEP12440.1 - 1.2e-06 28.3 4.2 1.2e-06 28.3 2.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.4 CEP12440.1 - 0.2 11.8 14.4 1.4 9.1 10.0 2.2 1 1 0 1 1 1 0 Learning-associated protein Atg31 PF09795.4 CEP12440.1 - 0.31 10.7 4.5 0.76 9.4 3.0 1.7 1 1 0 1 1 1 0 Autophagy-related protein 31 SLX9 PF15341.1 CEP12440.1 - 1.9 8.9 14.7 4.3 7.8 10.2 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Voldacs PF03517.8 CEP12441.1 - 5.1e-28 97.6 1.0 8.9e-28 96.8 0.7 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF4448 PF14610.1 CEP12442.1 - 1.2e-09 37.8 2.0 7.5e-09 35.3 1.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Cyt-b5 PF00173.23 CEP12443.1 - 1.1e-23 82.8 0.3 1.1e-23 82.8 0.2 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CEP12443.1 - 2.8e-07 30.9 27.0 3.4e-07 30.6 16.7 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Kua-UEV1_localn PF10520.4 CEP12443.1 - 2.4 7.7 10.8 2 8.0 2.5 2.5 2 0 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain DDE_3 PF13358.1 CEP12444.1 - 3.8e-19 68.8 0.6 6.1e-19 68.2 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP12444.1 - 2.4e-16 59.5 0.7 5.5e-16 58.3 0.5 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP12444.1 - 6.7e-10 39.1 0.6 1.2e-09 38.3 0.2 1.6 2 0 0 2 2 1 1 Winged helix-turn helix TrmB PF01978.14 CEP12444.1 - 7.2e-05 22.4 0.2 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.1 CEP12444.1 - 0.00012 21.5 0.0 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP12444.1 - 0.00016 22.4 1.7 0.00045 20.9 1.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP12444.1 - 0.00048 20.0 0.2 0.013 15.4 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 CEP12444.1 - 0.0005 19.3 0.1 0.076 12.4 0.0 3.1 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding KorB PF08535.5 CEP12444.1 - 0.0011 19.0 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 KorB domain HTH_7 PF02796.10 CEP12444.1 - 0.0012 18.6 1.2 0.051 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 CEP12444.1 - 0.0013 18.2 0.4 0.18 11.5 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain LacI PF00356.16 CEP12444.1 - 0.0032 17.0 0.2 0.21 11.2 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.5 CEP12444.1 - 0.026 14.1 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_17 PF12728.2 CEP12444.1 - 0.044 14.0 0.0 15 5.9 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.2 CEP12444.1 - 0.068 13.2 1.1 13 5.9 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain Mor PF08765.6 CEP12444.1 - 0.097 12.4 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family SUR7 PF06687.7 CEP12445.1 - 9.6e-19 67.7 15.8 1.4e-18 67.2 10.6 1.6 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CEP12445.1 - 1.1 8.9 16.6 0.13 11.9 7.0 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DDE_3 PF13358.1 CEP12447.1 - 4.7e-25 88.0 0.1 7.1e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TpcC PF12642.2 CEP12447.1 - 0.056 12.9 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Senescence PF06911.7 CEP12448.1 - 0.00082 19.1 13.0 0.0011 18.7 9.0 1.2 1 0 0 1 1 1 1 Senescence-associated protein DUF3833 PF12915.2 CEP12448.1 - 2.4 7.3 7.7 0.18 11.0 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3833) SseC PF04888.7 CEP12448.1 - 3.1 7.0 26.1 13 5.0 18.1 1.9 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF2076 PF09849.4 CEP12449.1 - 0.07 13.1 1.2 0.098 12.6 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MOZ_SAS PF01853.13 CEP12450.1 - 3.2e-90 300.4 1.0 4.4e-90 299.9 0.7 1.2 1 0 0 1 1 1 1 MOZ/SAS family PX PF00787.19 CEP12450.1 - 0.031 14.0 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 PX domain Acetyltransf_7 PF13508.1 CEP12450.1 - 0.07 13.3 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP12450.1 - 0.092 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HTH_11 PF08279.7 CEP12450.1 - 0.15 11.7 0.3 0.29 10.8 0.2 1.4 1 0 0 1 1 1 0 HTH domain Tudor-knot PF11717.3 CEP12451.1 - 2.1e-20 72.1 0.1 8.2e-20 70.2 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Sdh_cyt PF01127.17 CEP12452.1 - 8.1e-25 87.0 3.0 1.1e-24 86.5 2.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mito_carr PF00153.22 CEP12454.1 - 2.7e-70 232.1 4.5 9.7e-23 79.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CEP12454.1 - 1e-06 28.7 0.9 4.6e-05 23.4 0.4 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CEP12454.1 - 0.00013 21.5 0.0 4.3 7.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CEP12454.1 - 0.00023 20.7 0.0 0.00097 18.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CEP12454.1 - 0.018 14.3 0.1 0.37 10.2 0.0 2.7 3 0 0 3 3 3 0 EF hand ApoO PF09769.4 CEP12455.1 - 5.1e-30 104.2 6.6 3.9e-28 98.1 0.2 2.3 1 1 1 2 2 2 2 Apolipoprotein O ApoLp-III PF07464.6 CEP12455.1 - 3.7e-07 30.2 9.7 6.1e-06 26.3 3.6 2.2 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.13 CEP12455.1 - 8e-07 28.7 9.5 1e-06 28.3 3.0 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain PspA_IM30 PF04012.7 CEP12455.1 - 0.001 18.4 1.8 0.001 18.4 1.2 2.2 2 0 0 2 2 2 1 PspA/IM30 family Fzo_mitofusin PF04799.8 CEP12455.1 - 0.0035 16.7 1.2 0.0035 16.7 0.8 1.7 2 0 0 2 2 2 1 fzo-like conserved region Prominin PF05478.6 CEP12455.1 - 0.0037 14.8 4.3 0.015 12.9 0.9 2.0 2 0 0 2 2 2 1 Prominin ISG65-75 PF11727.3 CEP12455.1 - 0.0095 15.0 3.3 0.0095 15.0 2.3 2.0 2 0 0 2 2 2 1 Invariant surface glycoprotein DUF2681 PF10883.3 CEP12455.1 - 0.01 16.0 7.4 0.14 12.4 3.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Tweety PF04906.8 CEP12455.1 - 0.013 13.9 0.9 0.013 13.9 0.6 1.8 2 0 0 2 2 2 0 Tweety DUF883 PF05957.8 CEP12455.1 - 0.015 15.6 10.6 0.063 13.6 2.9 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 CEP12455.1 - 0.052 13.3 5.8 0.28 11.0 1.6 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HisKA_3 PF07730.8 CEP12455.1 - 0.06 13.7 1.6 3.1 8.1 0.1 3.3 2 1 1 3 3 3 0 Histidine kinase Fib_alpha PF08702.5 CEP12455.1 - 0.078 13.0 12.7 0.091 12.8 4.3 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Phasin PF05597.6 CEP12455.1 - 0.08 12.7 11.0 1.5 8.5 0.4 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.2 CEP12455.1 - 0.084 13.2 11.9 0.12 12.7 4.3 3.2 2 1 0 2 2 2 0 YtxH-like protein Reticulon PF02453.12 CEP12455.1 - 0.14 11.7 0.2 3.5 7.2 0.0 2.6 2 1 0 2 2 2 0 Reticulon IncA PF04156.9 CEP12455.1 - 0.14 11.7 1.1 0.37 10.3 0.2 2.1 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 CEP12455.1 - 0.15 11.9 4.7 0.2 11.4 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YfcL PF08891.6 CEP12455.1 - 0.15 12.0 2.3 0.25 11.3 0.4 2.1 2 0 0 2 2 2 0 YfcL protein DUF3631 PF12307.3 CEP12455.1 - 0.29 11.0 6.1 3.3 7.5 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3631) Lipase_GDSL_3 PF14606.1 CEP12455.1 - 0.34 10.6 4.4 0.14 11.9 0.7 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family BMFP PF04380.8 CEP12455.1 - 0.35 11.0 5.9 1.2 9.3 1.2 3.2 3 1 0 3 3 3 0 Membrane fusogenic activity COG5 PF10392.4 CEP12455.1 - 0.51 10.2 6.3 1.6 8.6 1.6 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF972 PF06156.8 CEP12455.1 - 4.3 7.7 7.3 1 9.7 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) COG2 PF06148.6 CEP12455.1 - 4.8 7.0 6.6 13 5.6 2.9 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CH PF00307.26 CEP12456.1 - 2.2e-14 53.3 0.0 2.9e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.13 CEP12456.1 - 0.00069 18.9 5.3 0.0015 17.8 3.7 1.4 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.3 CEP12456.1 - 0.0033 17.0 0.0 0.0063 16.1 0.0 1.5 1 1 0 1 1 1 1 CAMSAP CH domain DUF4163 PF13739.1 CEP12456.1 - 0.95 10.2 6.1 1.5 9.6 2.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4163) zf-C2H2 PF00096.21 CEP12457.1 - 1.6e-13 50.0 18.0 0.0001 22.4 0.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type Myb_DNA-binding PF00249.26 CEP12457.1 - 1.8e-13 50.2 1.0 5e-13 48.8 0.4 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP12457.1 - 7.5e-12 45.1 3.1 1.7e-11 44.0 1.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-H2C2_2 PF13465.1 CEP12457.1 - 1.8e-10 40.5 16.3 2.7e-06 27.3 0.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP12457.1 - 1.6e-08 34.3 14.6 0.0081 16.4 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger CHDCT2 PF08074.6 CEP12457.1 - 0.0037 17.0 0.1 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain zf-C2H2_6 PF13912.1 CEP12457.1 - 0.0091 15.8 8.9 0.014 15.2 0.4 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger UBA_4 PF14555.1 CEP12457.1 - 0.029 13.9 0.2 0.068 12.7 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain Rap1_C PF11626.3 CEP12457.1 - 0.14 12.1 0.3 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_jaz PF12171.3 CEP12457.1 - 0.75 10.0 8.2 5 7.3 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 CEP12457.1 - 3.3 7.5 10.3 11 5.9 3.7 3.2 2 1 1 3 3 3 0 Transposase zinc-ribbon domain C1_4 PF07975.7 CEP12457.1 - 4.6 7.3 5.8 4.2 7.4 2.3 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 CEP12457.1 - 8.2 6.4 6.6 16 5.5 0.3 3.0 1 1 2 3 3 3 0 Zinc ribbon domain HLH PF00010.21 CEP12458.1 - 3.6e-15 55.3 0.8 1.3e-14 53.5 0.6 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.1 CEP12458.1 - 0.21 12.0 0.1 0.21 12.0 0.1 3.1 4 1 0 4 4 4 0 Vascular protein family Vasculin-like 1 GATA PF00320.22 CEP12459.1 - 5.4e-33 112.0 17.6 3.1e-17 61.6 1.9 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CEP12459.1 - 0.00011 21.4 5.6 0.011 15.0 0.6 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 CEP12459.1 - 0.058 13.2 6.6 1.1 9.1 0.2 2.9 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CEP12459.1 - 0.073 13.0 1.6 8.1 6.4 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 CEP12459.1 - 0.087 12.4 4.1 1.9 8.1 0.2 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-CHY PF05495.7 CEP12459.1 - 0.44 10.7 3.5 3.2 7.9 0.1 2.7 3 0 0 3 3 3 0 CHY zinc finger zf-ribbon_3 PF13248.1 CEP12459.1 - 0.45 9.7 9.4 5.1 6.4 0.3 3.0 2 1 0 2 2 2 0 zinc-ribbon domain RRN7 PF11781.3 CEP12459.1 - 0.53 9.8 6.2 7.5 6.1 0.8 2.6 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_3 PF13878.1 CEP12459.1 - 1.6 8.3 7.5 6.9 6.3 0.1 3.5 3 1 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO Prim_Zn_Ribbon PF08273.7 CEP12459.1 - 7.7 6.6 9.7 17 5.5 0.6 2.8 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase PBP PF01161.15 CEP12460.1 - 4.7e-25 88.1 0.1 5.4e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ras PF00071.17 CEP12461.1 - 9.7e-49 164.8 0.2 1.2e-48 164.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP12461.1 - 1.2e-13 51.5 0.0 3.2e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP12461.1 - 5.4e-10 38.7 0.0 7e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP12461.1 - 7.8e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP12461.1 - 8.5e-05 21.7 0.0 0.00012 21.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RTA1 PF04479.8 CEP12462.1 - 9.9e-38 129.8 12.4 1.6e-37 129.2 8.6 1.2 1 0 0 1 1 1 1 RTA1 like protein FixQ PF05545.6 CEP12462.1 - 1.8 8.2 7.7 1 9.0 0.3 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ RTA1 PF04479.8 CEP12463.1 - 1.5e-38 132.5 9.1 2.4e-38 131.9 6.3 1.3 1 0 0 1 1 1 1 RTA1 like protein Pal1 PF08316.6 CEP12464.1 - 0.021 15.2 0.0 0.6 10.5 0.0 2.2 2 0 0 2 2 2 0 Pal1 cell morphology protein LEAP-2 PF07359.6 CEP12464.1 - 0.091 12.4 1.8 0.26 10.9 1.2 1.9 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.13 CEP12464.1 - 2.7 8.1 21.1 0.27 11.3 4.9 3.3 3 0 0 3 3 3 0 EB module Sds3 PF08598.6 CEP12465.1 - 6.9e-19 68.1 15.2 6.9e-19 68.1 10.6 1.8 2 0 0 2 2 2 1 Sds3-like DUF1447 PF07288.6 CEP12465.1 - 0.1 12.3 5.2 2 8.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) Innate_immun PF12782.2 CEP12465.1 - 7.6 5.6 16.9 0.14 11.3 6.9 1.6 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family zf-RING_2 PF13639.1 CEP12466.1 - 1.3e-12 47.3 6.8 3.4e-12 45.9 4.8 1.7 1 1 0 1 1 1 1 Ring finger domain PA PF02225.17 CEP12466.1 - 1.5e-12 47.0 0.0 2.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.20 CEP12466.1 - 3.1e-08 33.1 2.1 4.9e-08 32.4 1.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEP12466.1 - 1.9e-06 27.8 2.9 5.3e-06 26.4 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CEP12466.1 - 1.1e-05 25.2 2.7 2.6e-05 24.1 1.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP12466.1 - 0.00051 19.7 4.3 0.00051 19.7 3.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CEP12466.1 - 0.015 15.0 2.7 0.039 13.7 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CEP12466.1 - 0.13 12.2 6.7 0.48 10.4 4.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CEP12466.1 - 0.16 12.0 5.3 0.12 12.4 2.3 1.9 2 1 0 2 2 2 0 RING-variant domain PHD PF00628.24 CEP12466.1 - 0.17 11.5 5.4 0.31 10.7 3.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 CEP12466.1 - 0.28 11.0 3.7 0.56 10.1 2.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 CEP12466.1 - 0.4 10.7 4.3 0.86 9.6 3.0 1.6 1 0 0 1 1 1 0 RING-like domain RNase_P_Rpp14 PF01900.14 CEP12467.1 - 3.6e-16 58.9 0.0 5.6e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family Aldo_ket_red PF00248.16 CEP12468.1 - 2.1e-56 190.8 0.0 2.5e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_7 PF02796.10 CEP12468.1 - 0.27 11.1 1.5 0.55 10.1 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Aa_trans PF01490.13 CEP12469.1 - 2.7e-64 217.1 28.7 3.3e-64 216.8 19.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 CEP12469.1 - 0.007 15.0 24.5 0.17 10.5 0.7 4.0 2 2 1 3 3 3 3 Spore germination protein Gp23 PF07068.6 CEP12469.1 - 0.14 10.6 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Major capsid protein Gp23 Not3 PF04065.10 CEP12470.1 - 1.1e-93 312.8 32.2 1.6e-93 312.2 22.3 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CEP12470.1 - 1.8e-45 154.0 10.6 1.8e-45 154.0 7.3 2.9 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Met_asp_mut_E PF06368.6 CEP12470.1 - 0.099 10.8 0.9 0.15 10.2 0.1 1.6 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) COG5 PF10392.4 CEP12470.1 - 8.3 6.3 12.0 35 4.3 2.5 4.0 2 1 2 4 4 4 0 Golgi transport complex subunit 5 DUF948 PF06103.6 CEP12470.1 - 8.7 6.2 7.0 28 4.6 0.2 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) C-term_anchor PF13461.1 CEP12471.1 - 0.022 15.1 0.0 0.095 13.1 0.0 2.0 2 0 0 2 2 2 0 Cell-wall surface anchor repeat NiFeSe_Hases PF00374.14 CEP12472.1 - 0.072 11.8 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase PrmA PF06325.8 CEP12472.1 - 0.086 11.9 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RVT_1 PF00078.22 CEP12473.1 - 1.6e-12 47.2 0.1 2.7e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP12474.1 - 6.5e-26 91.0 0.0 1.2e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP12474.1 - 7.7e-13 48.0 0.2 5.3e-12 45.4 0.0 2.5 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP12474.1 - 8.7e-05 22.5 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_Tnp_IS1595 PF12760.2 CEP12475.1 - 0.95 9.3 6.0 1.1 9.1 1.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Fer4_11 PF13247.1 CEP12475.1 - 1.9 8.4 6.4 15 5.5 0.9 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain vATP-synt_E PF01991.13 CEP12476.1 - 7.5e-57 191.8 11.4 8.8e-57 191.5 7.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit LRR_8 PF13855.1 CEP12477.1 - 1.4e-32 111.2 39.2 1.4e-10 40.7 5.6 7.0 3 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 CEP12477.1 - 8.5e-31 105.0 40.1 1e-07 31.3 4.2 8.1 6 1 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP12477.1 - 6.1e-19 65.1 49.5 0.079 13.0 0.0 14.0 15 0 0 15 15 15 9 Leucine Rich Repeat LRR_7 PF13504.1 CEP12477.1 - 6e-13 46.7 42.0 0.46 10.8 0.1 13.2 14 0 0 14 14 14 7 Leucine rich repeat LRR_6 PF13516.1 CEP12477.1 - 5e-05 22.9 37.3 0.14 12.3 0.1 10.3 12 0 0 12 12 12 4 Leucine Rich repeat LRR_9 PF14580.1 CEP12477.1 - 9.6 5.7 12.1 5.5 6.5 1.1 3.1 3 1 0 3 3 3 0 Leucine-rich repeat Glyco_transf_15 PF01793.11 CEP12478.1 - 3.9e-92 308.7 12.7 4.7e-92 308.4 8.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-met PF12874.2 CEP12479.1 - 3.9e-09 36.4 33.9 7e-05 22.8 0.8 7.9 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP12479.1 - 7.1e-08 32.3 30.9 0.00092 19.2 0.5 6.8 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CEP12479.1 - 5.6e-07 29.6 18.3 0.14 12.2 0.2 5.4 4 1 0 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CEP12479.1 - 0.0042 17.3 56.1 0.03 14.6 1.2 7.3 7 0 0 7 7 7 4 Zinc finger, C2H2 type DUF2757 PF10955.3 CEP12479.1 - 0.6 10.3 5.4 6.1 7.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) zf-C2H2_4 PF13894.1 CEP12479.1 - 0.76 10.2 51.7 0.24 11.8 0.4 7.3 7 1 0 7 7 7 0 C2H2-type zinc finger DZR PF12773.2 CEP12479.1 - 1.4 8.7 21.2 2 8.3 0.2 4.7 3 3 0 3 3 3 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 CEP12479.1 - 2.1 8.4 9.6 46 4.1 0.0 4.9 5 0 0 5 5 5 0 Zinc-binding domain of primase-helicase GBP_repeat PF02526.9 CEP12479.1 - 2.5 7.5 0.0 2.5 7.5 0.0 4.1 4 1 0 4 4 4 0 Glycophorin-binding protein zf-AD PF07776.10 CEP12479.1 - 4.2 7.4 12.1 9.8 6.2 0.2 4.4 4 1 0 4 4 4 0 Zinc-finger associated domain (zf-AD) DUF629 PF04780.7 CEP12479.1 - 5.4 5.4 16.0 7.4 4.9 0.8 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF629) Inos-1-P_synth PF01658.12 CEP12480.1 - 0.085 12.6 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF1547 PF07577.6 CEP12480.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) CSTF2_hinge PF14327.1 CEP12481.1 - 9e-23 80.1 6.8 9e-23 80.1 4.7 2.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 CEP12481.1 - 5.1e-21 74.0 0.0 1.6e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12481.1 - 2.4e-15 56.2 0.0 1.8e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CEP12481.1 - 6.2e-11 41.3 7.1 6.2e-11 41.3 4.9 2.5 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 CEP12481.1 - 2.7e-08 33.5 0.0 1.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1183 PF06682.7 CEP12481.1 - 0.18 11.4 9.3 0.32 10.5 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) MgtE_N PF03448.12 CEP12481.1 - 0.2 11.9 2.0 3.6 7.9 0.0 3.1 4 0 0 4 4 4 0 MgtE intracellular N domain Extensin_2 PF04554.8 CEP12481.1 - 3.4 7.6 33.7 0.88 9.4 12.1 2.3 2 0 0 2 2 2 0 Extensin-like region DUF788 PF05620.6 CEP12482.1 - 5.7e-53 179.2 1.5 6.4e-53 179.1 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Lgl_C PF08596.5 CEP12483.1 - 1.9e-14 52.9 0.0 1.2e-12 47.0 0.0 3.1 3 0 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CEP12483.1 - 4.1e-06 26.4 4.4 0.00012 21.8 0.2 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Synaptobrevin PF00957.16 CEP12483.1 - 0.0068 15.9 0.3 0.016 14.7 0.2 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF2442 PF10387.4 CEP12483.1 - 0.11 12.4 0.0 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Ribosomal_L27 PF01016.14 CEP12484.1 - 1.5e-39 133.6 0.7 1.8e-39 133.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein PDZ_1 PF12812.2 CEP12485.1 - 8.3e-28 96.1 0.0 7.3e-19 67.4 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 CEP12485.1 - 1.7e-16 59.8 3.5 0.0026 17.6 0.0 5.1 5 0 0 5 5 5 4 PDZ domain Trypsin_2 PF13365.1 CEP12485.1 - 5.2e-10 39.3 0.0 5.2e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 CEP12485.1 - 8e-07 29.1 3.8 0.44 10.7 0.0 4.4 5 0 0 5 5 5 3 PDZ domain (Also known as DHR or GLGF) Peptidase_S7 PF00949.16 CEP12485.1 - 0.0084 15.5 1.3 0.023 14.1 0.9 1.6 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 CEP12485.1 - 0.031 13.6 0.9 0.06 12.6 0.3 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF31) ResIII PF04851.10 CEP12485.1 - 0.034 13.9 0.1 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit VirK PF06903.7 CEP12485.1 - 0.12 12.1 0.0 0.45 10.2 0.0 1.9 1 0 0 1 1 1 0 VirK protein Peptidase_S46 PF10459.4 CEP12485.1 - 0.19 10.1 0.1 0.31 9.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase S46 Ribosomal_L27 PF01016.14 CEP12486.1 - 4e-25 87.4 0.2 5.1e-25 87.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein DMRL_synthase PF00885.14 CEP12487.1 - 2.3e-45 153.8 1.2 1.1e-30 106.2 0.3 2.0 1 1 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Spo0A_C PF08769.6 CEP12487.1 - 0.0079 16.0 0.1 0.88 9.4 0.0 2.3 2 0 0 2 2 2 2 Sporulation initiation factor Spo0A C terminal Vps5 PF09325.5 CEP12488.1 - 5.8e-13 48.6 8.0 8.5e-13 48.1 5.5 1.1 1 0 0 1 1 1 1 Vps5 C terminal like DUF4423 PF14394.1 CEP12488.1 - 0.0038 16.7 0.4 0.0079 15.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) Abhydrolase_5 PF12695.2 CEP12489.1 - 5.5e-17 61.8 0.0 7.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP12489.1 - 4e-12 46.4 0.0 7.7e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP12489.1 - 1.4e-05 24.7 0.2 0.00032 20.3 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 CEP12489.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CEP12489.1 - 0.0021 17.5 0.0 0.18 11.2 0.0 2.8 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase DUF1057 PF06342.7 CEP12489.1 - 0.006 15.4 0.0 0.011 14.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.15 CEP12489.1 - 0.0074 16.5 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Lipase PF00151.14 CEP12489.1 - 0.0099 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Lipase DUF676 PF05057.9 CEP12489.1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 CEP12489.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CEP12489.1 - 0.036 13.4 0.0 0.11 11.8 0.0 1.7 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 CEP12489.1 - 0.04 13.5 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Methyltransf_23 PF13489.1 CEP12490.1 - 3.4e-14 52.8 0.0 5.4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP12490.1 - 9.3e-14 51.7 0.0 2.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP12490.1 - 4.5e-11 42.5 0.0 4e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP12490.1 - 7.2e-11 42.3 0.0 1.9e-10 41.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP12490.1 - 4e-08 33.6 0.0 8.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP12490.1 - 5.2e-08 33.4 0.0 2.7e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP12490.1 - 7.8e-06 25.0 0.0 5.6e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 CEP12490.1 - 1.8e-05 24.0 0.0 4.1e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Ubie_methyltran PF01209.13 CEP12490.1 - 6.8e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 CEP12490.1 - 0.00014 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.11 CEP12490.1 - 0.00023 19.6 0.0 0.0079 14.5 0.0 2.0 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 CEP12490.1 - 0.0018 18.2 0.0 0.0074 16.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 CEP12490.1 - 0.04 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 CEP12490.1 - 0.098 11.9 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MetW PF07021.7 CEP12490.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW bZIP_2 PF07716.10 CEP12492.1 - 3.1e-13 49.3 9.5 3.6e-13 49.1 3.5 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP12492.1 - 3.7e-11 42.8 6.2 3.7e-11 42.8 4.3 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 CEP12492.1 - 0.00016 21.8 4.2 0.00017 21.8 2.0 1.7 1 1 1 2 2 2 1 bZIP Maf transcription factor Striatin PF08232.7 CEP12492.1 - 0.0057 16.9 2.5 0.0057 16.9 1.7 2.1 1 1 1 2 2 2 1 Striatin family ADIP PF11559.3 CEP12492.1 - 0.0066 16.3 4.8 0.0066 16.3 3.3 1.8 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 CEP12492.1 - 0.0088 15.5 2.3 0.011 15.2 0.9 1.6 1 1 0 1 1 1 1 Septum formation initiator Spc7 PF08317.6 CEP12492.1 - 0.018 13.7 4.0 0.027 13.1 2.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CEP12492.1 - 0.027 13.6 2.6 0.037 13.2 1.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CEP12492.1 - 0.17 11.5 11.5 0.093 12.4 4.0 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 CEP12492.1 - 0.26 9.0 6.3 0.34 8.7 4.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CEP12492.1 - 0.28 10.1 6.5 0.38 9.7 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 M PF02370.11 CEP12492.1 - 0.31 11.5 5.9 2 9.0 0.3 3.5 2 1 1 3 3 3 0 M protein repeat Sugarporin_N PF11471.3 CEP12492.1 - 0.38 10.4 6.0 0.22 11.2 0.6 2.7 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension IncA PF04156.9 CEP12492.1 - 2.1 7.8 8.9 3.3 7.2 6.1 1.3 1 1 0 1 1 1 0 IncA protein DUF4140 PF13600.1 CEP12492.1 - 4.6 7.7 7.1 2.2 8.7 1.8 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NmrA PF05368.8 CEP12493.1 - 2.7e-15 56.2 0.2 2.3e-14 53.2 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CEP12493.1 - 3.3e-13 50.0 0.0 2.2e-12 47.3 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CEP12493.1 - 4.1e-05 23.1 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 CEP12493.1 - 0.00038 20.4 0.1 0.001 19.0 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.20 CEP12493.1 - 0.0065 16.4 0.1 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_7 PF13241.1 CEP12493.1 - 0.027 14.7 0.0 0.082 13.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 CEP12493.1 - 0.028 14.7 0.1 0.067 13.4 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CEP12493.1 - 0.039 13.7 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 CEP12493.1 - 0.042 12.5 0.0 0.074 11.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Vac14_Fig4_bd PF11916.3 CEP12494.1 - 2.7e-81 271.0 9.4 5.9e-81 269.9 6.5 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CEP12494.1 - 3.7e-47 158.6 0.3 3.6e-41 139.4 0.0 4.5 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CEP12494.1 - 9.2e-13 47.1 2.0 0.0027 17.6 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 CEP12494.1 - 2.2e-09 37.4 0.4 0.12 12.6 0.0 5.2 5 0 0 5 5 5 3 HEAT repeats Arm PF00514.18 CEP12494.1 - 9.6e-08 31.5 0.2 1.9 8.4 0.0 5.7 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CEP12494.1 - 1.8e-06 28.2 4.9 0.62 10.6 0.1 7.1 8 1 1 9 9 9 2 HEAT-like repeat DDHD PF02862.12 CEP12494.1 - 3.5 7.3 19.8 0.48 10.1 2.4 3.5 3 0 0 3 3 3 0 DDHD domain RhoGEF PF00621.15 CEP12495.1 - 0.071 12.9 9.0 1.8 8.3 0.3 4.2 3 1 1 4 4 4 0 RhoGEF domain Myb_DNA-bind_6 PF13921.1 CEP12496.1 - 1.9e-08 34.2 6.7 0.00058 19.9 1.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP12496.1 - 3.2e-06 27.1 2.2 0.00041 20.3 0.4 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CEP12496.1 - 0.0062 16.3 1.2 0.013 15.4 0.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PUL PF08324.6 CEP12497.1 - 3.7e-42 143.9 1.2 7.3e-42 143.0 0.8 1.5 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 CEP12497.1 - 1.4e-39 132.5 8.4 2.8e-07 30.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PFU PF09070.6 CEP12497.1 - 2.2e-37 127.6 0.5 5.6e-37 126.2 0.3 1.8 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) HATPase_c PF02518.21 CEP12497.1 - 1.6e-26 92.2 0.0 3.1e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEP12497.1 - 4.6e-26 91.0 0.0 2.2e-25 88.8 0.0 2.3 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase_Tyr PF07714.12 CEP12497.1 - 1.1e-22 80.3 0.0 3.1e-21 75.6 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CEP12497.1 - 1.6e-16 60.2 0.0 6.5e-16 58.2 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain HisKA PF00512.20 CEP12497.1 - 1.5e-15 56.9 0.0 3.9e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Peripla_BP_4 PF13407.1 CEP12497.1 - 3.1e-13 49.6 3.4 1.9e-08 34.0 0.1 3.0 3 0 0 3 3 3 2 Periplasmic binding protein domain BBS2_Mid PF14783.1 CEP12497.1 - 6.2e-05 22.7 0.1 0.024 14.4 0.0 3.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Peripla_BP_1 PF00532.16 CEP12497.1 - 0.00014 21.1 0.0 0.0064 15.7 0.0 2.5 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family NCD3G PF07562.9 CEP12497.1 - 0.014 15.0 1.2 0.048 13.3 0.8 1.9 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR SKG6 PF08693.5 CEP12497.1 - 0.04 13.2 1.6 0.088 12.1 1.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PMAIP1 PF15150.1 CEP12497.1 - 0.19 11.5 0.4 0.46 10.2 0.3 1.7 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced VSP PF03302.8 CEP12497.1 - 0.22 10.1 9.6 0.4 9.2 6.7 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein GCC2_GCC3 PF07699.8 CEP12497.1 - 1.2 8.8 14.6 0.41 10.2 7.5 2.3 2 1 0 2 2 1 0 GCC2 and GCC3 MFS_1 PF07690.11 CEP12498.1 - 3.2e-50 170.8 30.6 1.3e-46 158.9 11.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP12498.1 - 1.7e-13 49.9 10.8 1.7e-13 49.9 7.5 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CEP12498.1 - 2.2e-08 32.7 8.6 4.3e-08 31.8 6.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CEP12498.1 - 0.002 16.3 5.7 0.002 16.3 4.0 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 CEP12498.1 - 0.12 10.4 8.8 0.72 7.8 3.1 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PIP5K PF01504.13 CEP12499.1 - 5.6e-86 287.7 2.3 1.3e-85 286.5 1.6 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-C2H2 PF00096.21 CEP12499.1 - 5.8e-09 35.7 11.0 0.00018 21.6 1.2 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP12499.1 - 4.4e-06 26.7 2.4 4.4e-06 26.7 1.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP12499.1 - 0.0017 18.5 17.5 0.0022 18.1 0.7 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP12499.1 - 0.041 14.0 0.1 0.041 14.0 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP12499.1 - 0.11 12.7 0.2 0.11 12.7 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Hexokinase_2 PF03727.11 CEP12500.1 - 1.2e-57 194.9 0.1 1.6e-57 194.5 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEP12500.1 - 7.1e-43 146.3 0.0 1.4e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase NTF2 PF02136.15 CEP12501.1 - 5e-29 101.0 0.1 5e-29 101.0 0.1 2.4 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 CEP12501.1 - 4.1e-12 45.5 0.1 9.4e-12 44.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12501.1 - 6.3e-11 42.1 0.1 1.4e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12501.1 - 2.9e-05 23.8 0.1 6e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.2 CEP12502.1 - 3.7e-08 33.2 0.1 6.5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP12502.1 - 8.3e-08 32.1 0.0 1.8e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 CEP12502.1 - 0.0025 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 U1 zinc finger Viral_P18 PF04521.8 CEP12502.1 - 0.073 12.5 5.9 0.1 12.0 3.3 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Hex_IIIa PF02455.11 CEP12502.1 - 0.71 8.4 7.8 0.81 8.2 5.4 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF812 PF05667.6 CEP12502.1 - 2.9 6.3 18.3 4.4 5.6 12.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1777 PF08648.7 CEP12502.1 - 4.6 6.9 28.3 4.4e+02 0.4 19.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) F-box-like PF12937.2 CEP12503.1 - 1.4e-08 34.3 0.5 5.7e-08 32.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP12503.1 - 8.3e-08 31.6 0.1 1.3e-06 27.8 0.0 3.0 2 0 0 2 2 2 1 F-box domain Methyltransf_11 PF08241.7 CEP12504.1 - 5e-15 55.7 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP12504.1 - 5.4e-09 35.9 0.0 7.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP12504.1 - 3.8e-07 29.8 0.0 6.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP12504.1 - 1.4e-06 28.5 0.0 7.9e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP12504.1 - 2.1e-06 28.1 0.0 9.6e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP12504.1 - 2.1e-05 23.7 0.0 5.5e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 CEP12504.1 - 0.0052 15.5 0.0 0.022 13.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.2 CEP12504.1 - 0.0096 16.4 0.1 0.032 14.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CEP12504.1 - 0.034 13.5 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Staphopain_pro PF14731.1 CEP12505.1 - 0.028 14.1 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Staphopain proregion Coat_F PF07875.7 CEP12505.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Coat F domain SPRY PF00622.23 CEP12509.1 - 4.5e-27 94.5 5.0 5.3e-26 91.1 0.5 2.8 3 0 0 3 3 3 1 SPRY domain Arm PF00514.18 CEP12509.1 - 2.4e-08 33.5 1.1 0.16 11.8 0.0 6.0 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CEP12509.1 - 5.2e-05 23.5 4.5 0.63 10.4 0.1 4.4 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.4 CEP12509.1 - 0.029 14.1 1.2 0.1 12.3 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 CEP12509.1 - 0.065 13.7 0.0 10 6.7 0.0 3.2 2 0 0 2 2 2 0 HEAT-like repeat PIF1 PF05970.9 CEP12512.1 - 9.3e-18 64.3 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP12512.1 - 9.1e-06 23.7 0.0 1e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP12512.1 - 0.00028 20.9 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain rve PF00665.21 CEP12513.1 - 5.3e-19 68.4 0.0 1.4e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP12513.1 - 0.053 13.0 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Kinesin PF00225.18 CEP12514.1 - 1.2e-98 329.9 0.1 1.2e-98 329.9 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 CEP12514.1 - 4.4e-37 126.8 0.0 1.4e-36 125.2 0.0 2.0 2 0 0 2 2 2 1 Kinesin protein KIF1B PF12423.3 CEP12514.1 - 2e-10 40.5 0.4 8.6e-10 38.4 0.2 2.3 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 CEP12514.1 - 3e-08 33.6 0.1 3e-07 30.4 0.1 2.4 2 0 0 2 2 2 1 FHA domain PH PF00169.24 CEP12514.1 - 1.6e-05 25.0 0.0 0.00017 21.7 0.0 2.8 2 0 0 2 2 2 1 PH domain PBP1_TM PF14812.1 CEP12514.1 - 0.92 9.8 12.0 0.029 14.6 2.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_10 PF13460.1 CEP12515.1 - 3.2e-09 37.0 0.0 6.9e-09 35.9 0.0 1.6 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 CEP12515.1 - 3e-06 26.6 0.0 4.4e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CEP12515.1 - 0.007 15.0 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TIR_2 PF13676.1 CEP12515.1 - 0.041 14.0 0.2 0.63 10.2 0.0 2.6 2 1 1 3 3 3 0 TIR domain Prok-E2_D PF14460.1 CEP12515.1 - 0.098 12.1 0.1 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic E2 family D DUF3627 PF12299.3 CEP12515.1 - 0.12 12.4 0.1 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) Arylesterase PF01731.15 CEP12516.1 - 1.4e-09 37.8 0.9 4.6e-09 36.1 0.2 2.2 2 0 0 2 2 2 1 Arylesterase UQ_con PF00179.21 CEP12517.1 - 1.4e-53 180.1 0.0 1.5e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEP12517.1 - 9.3e-05 22.1 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CEP12517.1 - 0.00049 19.9 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CEP12517.1 - 0.03 13.9 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF846 PF05832.7 CEP12518.1 - 1e-53 180.8 10.1 1.3e-53 180.5 7.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.1 CEP12518.1 - 0.022 13.8 0.5 0.68 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) RseC_MucC PF04246.7 CEP12518.1 - 7.7 6.0 6.5 25 4.4 1.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Zn_clus PF00172.13 CEP12519.1 - 4.7e-08 32.8 7.1 9.4e-08 31.8 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FoP_duplication PF13865.1 CEP12520.1 - 2.4e-08 34.3 20.3 4.3e-07 30.2 14.1 2.4 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF3371 PF11851.3 CEP12520.1 - 0.034 14.8 0.1 0.037 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) THP2 PF09432.5 CEP12520.1 - 0.11 12.3 0.5 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 Tho complex subunit THP2 Hydrolase_6 PF13344.1 CEP12521.1 - 0.21 11.4 1.0 0.91 9.4 0.0 2.4 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Palm_thioest PF02089.10 CEP12522.1 - 9.6e-25 87.0 0.2 1.4e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF3393 PF11873.3 CEP12522.1 - 0.036 13.5 2.1 0.078 12.4 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) Ribosomal_L35p PF01632.14 CEP12524.1 - 1.5e-13 50.4 0.8 1.8e-13 50.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 zf-C4H2 PF10146.4 CEP12525.1 - 8.6e-09 35.7 14.8 1.1e-08 35.4 10.3 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Baculo_PEP_C PF04513.7 CEP12525.1 - 0.16 11.8 4.4 0.16 11.8 1.9 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CEP12525.1 - 0.48 9.9 17.5 0.67 9.5 11.8 1.5 1 1 0 1 1 1 0 IncA protein Tweety PF04906.8 CEP12525.1 - 1.4 7.2 4.7 2.9 6.1 2.4 1.9 1 1 1 2 2 2 0 Tweety DUF948 PF06103.6 CEP12525.1 - 1.5 8.7 4.8 4.6 7.1 2.6 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) eIF3_N PF09440.5 CEP12525.1 - 2.9 8.0 9.1 0.3 11.2 3.3 1.6 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain COG2 PF06148.6 CEP12525.1 - 4.3 7.2 10.9 1.5 8.6 3.0 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 CEP12525.1 - 5.9 4.6 10.6 6.4 4.4 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Methyltransf_18 PF12847.2 CEP12526.1 - 3.7e-10 40.3 0.0 7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP12526.1 - 8e-09 35.8 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP12526.1 - 5.5e-08 32.5 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP12526.1 - 1.4e-07 31.3 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP12526.1 - 8.4e-05 22.8 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP12526.1 - 0.00017 20.7 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CEP12526.1 - 0.00038 20.8 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP12526.1 - 0.00099 18.2 0.0 0.0034 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase SHQ1 PF04925.10 CEP12527.1 - 3.5e-65 219.0 1.5 6.7e-65 218.0 1.0 1.4 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.11 CEP12527.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 0 CS domain zf-RVT PF13966.1 CEP12528.1 - 0.00013 22.1 0.8 0.00028 21.1 0.5 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Cas_Cas4 PF01930.12 CEP12529.1 - 0.053 13.4 2.3 2.9 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF83 SWIB PF02201.13 CEP12529.1 - 0.081 12.6 0.2 2.5 7.8 0.0 2.5 2 1 0 2 2 2 0 SWIB/MDM2 domain DUF2135 PF09906.4 CEP12529.1 - 0.13 12.2 0.1 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) RE_AlwI PF09491.5 CEP12529.1 - 0.69 8.3 9.1 0.84 8.0 2.7 2.6 2 1 0 2 2 2 0 AlwI restriction endonuclease zf-RING_2 PF13639.1 CEP12531.1 - 9.8e-13 47.7 7.4 1.4e-12 47.1 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP12531.1 - 3.7e-09 36.5 2.5 6.5e-09 35.7 1.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CEP12531.1 - 3.1e-07 30.2 7.4 4.7e-07 29.7 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP12531.1 - 3.9e-07 29.6 3.6 5.7e-07 29.1 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP12531.1 - 8.9e-06 25.2 6.6 1.5e-05 24.5 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TFIIIC PF12660.2 CEP12531.1 - 2.9e-05 23.8 1.4 5e-05 23.1 0.9 1.3 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex zf-RING_UBOX PF13445.1 CEP12531.1 - 0.00023 20.8 1.3 0.0004 20.0 0.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CEP12531.1 - 0.00049 19.7 4.9 0.00084 19.0 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CEP12531.1 - 0.0017 18.1 3.7 0.0044 16.8 2.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 CEP12531.1 - 0.02 14.8 0.0 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 U-box domain zf-Nse PF11789.3 CEP12531.1 - 0.03 13.8 2.5 0.052 13.0 1.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FSA_C PF10479.4 CEP12531.1 - 0.062 11.3 0.0 0.062 11.3 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1719 PF08224.6 CEP12531.1 - 0.084 11.9 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Prok-RING_4 PF14447.1 CEP12531.1 - 0.11 12.0 3.5 0.27 10.8 2.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.1 CEP12531.1 - 0.14 11.9 3.3 0.19 11.4 0.2 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 CEP12531.1 - 0.27 10.8 3.6 0.47 10.0 2.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CEP12531.1 - 0.34 10.8 4.6 1 9.3 3.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3020 PF11223.3 CEP12532.1 - 1.4e-08 34.9 1.4 1.4e-08 34.9 1.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3020) DDE_3 PF13358.1 CEP12534.1 - 8.4e-12 45.0 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DEAD PF00270.24 CEP12535.1 - 1.4e-36 125.5 0.6 1.3e-35 122.4 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP12535.1 - 1.8e-17 62.9 0.0 5e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP12535.1 - 2.3e-07 30.8 0.3 7.5e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CEP12535.1 - 0.0017 17.2 0.1 0.0037 16.1 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CEP12535.1 - 0.013 15.6 0.5 0.31 11.2 0.2 2.9 1 1 1 2 2 2 0 AAA domain GCR1_C PF12550.3 CEP12536.1 - 2.5e-24 84.9 0.6 3.3e-24 84.5 0.4 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes MR_MLE_C PF13378.1 CEP12537.1 - 0.094 12.6 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 Enolase C-terminal domain-like RRM_1 PF00076.17 CEP12538.1 - 3.6e-40 135.4 0.0 6.3e-17 60.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12538.1 - 2.1e-22 78.8 0.0 3.3e-07 30.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12538.1 - 1.3e-21 76.1 0.1 3.6e-11 42.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP12538.1 - 2.8e-05 23.7 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CEP12538.1 - 0.00063 19.5 0.0 0.00063 19.5 0.0 3.2 5 0 0 5 5 5 1 RNA binding motif Suf PF05843.9 CEP12538.1 - 0.42 10.2 18.1 0.65 9.6 4.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CEP12538.1 - 4.5 5.3 44.8 0.24 9.5 10.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CEP12538.1 - 5.6 6.7 26.2 1 9.1 7.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) PAF-AH_p_II PF03403.8 CEP12539.1 - 4.9e-66 222.5 0.0 4.5e-65 219.3 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CEP12539.1 - 9.8e-16 57.8 0.0 1.4e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CEP12539.1 - 6.3e-10 38.3 0.0 2e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 CEP12539.1 - 1.2e-08 35.1 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP12539.1 - 7.2e-07 28.6 0.0 2.8e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.6 CEP12539.1 - 1.2e-05 24.2 0.0 0.00057 18.7 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 CEP12539.1 - 0.00076 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 CEP12539.1 - 0.022 14.0 0.0 0.065 12.5 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.20 CEP12539.1 - 0.06 12.9 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) CoA_binding PF02629.14 CEP12540.1 - 5.3e-30 103.7 3.7 7.5e-30 103.3 0.7 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CEP12540.1 - 1.9e-22 79.4 0.1 4e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CEP12540.1 - 9.1e-06 25.3 0.0 1.8e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CEP12540.1 - 8.4e-05 22.7 0.0 0.00023 21.3 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 CEP12540.1 - 0.0036 17.7 0.1 0.0073 16.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Rer1 PF03248.8 CEP12541.1 - 4.9e-76 254.2 7.2 4.9e-76 254.2 5.0 1.8 2 1 0 2 2 2 1 Rer1 family EI24 PF07264.6 CEP12541.1 - 0.0017 17.8 3.3 0.0026 17.2 2.3 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ku_PK_bind PF08785.6 CEP12541.1 - 0.043 13.7 0.5 0.043 13.7 0.4 2.7 1 1 1 2 2 2 0 Ku C terminal domain like IncA PF04156.9 CEP12541.1 - 0.19 11.3 6.8 0.13 11.8 2.3 2.3 2 0 0 2 2 2 0 IncA protein DUF2208 PF09973.4 CEP12541.1 - 0.32 10.2 4.2 0.77 8.9 2.9 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Retrotrans_gag PF03732.12 CEP12541.1 - 0.45 10.6 5.2 2.6 8.1 3.5 2.4 1 1 0 1 1 1 0 Retrotransposon gag protein Tweety PF04906.8 CEP12541.1 - 0.8 8.0 5.9 0.92 7.8 0.0 2.1 2 0 0 2 2 2 0 Tweety Innate_immun PF12782.2 CEP12542.1 - 3 6.9 13.7 1.3 8.1 7.8 1.5 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family PilX PF13681.1 CEP12543.1 - 0.11 13.0 4.2 3.9 8.0 3.2 2.5 2 1 0 2 2 2 0 Type IV pilus assembly protein PilX C-term Mucin PF01456.12 CEP12543.1 - 2.4 7.9 18.1 0.15 11.8 6.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Tetraspannin PF00335.15 CEP12544.1 - 6.8e-06 25.5 3.9 9.8e-06 24.9 2.7 1.2 1 0 0 1 1 1 1 Tetraspanin family Shisa PF13908.1 CEP12544.1 - 0.0093 16.1 0.3 0.011 15.9 0.2 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2416 PF10315.4 CEP12545.1 - 5.7e-13 49.0 0.7 8.4e-13 48.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Peptidase_M13_N PF05649.8 CEP12546.1 - 1.5e-64 218.4 2.3 1.6e-63 215.0 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 CEP12546.1 - 3.9e-38 130.6 0.0 9.3e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 SPX PF03105.14 CEP12546.1 - 2.7e-37 129.0 15.9 1.1e-36 127.0 11.0 2.1 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 CEP12546.1 - 2.8e-07 30.2 8.4 6.1e-07 29.2 5.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CEP12546.1 - 1e-06 28.4 9.2 2.6e-06 27.1 6.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEP12546.1 - 2.8e-06 26.9 7.5 6.9e-06 25.6 5.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEP12546.1 - 7.6e-06 25.4 8.9 2e-05 24.1 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP12546.1 - 4.7e-05 22.9 9.0 9.4e-05 22.0 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP12546.1 - 7e-05 22.7 10.7 7e-05 22.7 7.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP12546.1 - 0.042 13.5 7.3 0.13 11.9 5.0 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 CEP12546.1 - 0.31 10.5 5.7 0.76 9.3 3.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CEP12546.1 - 0.35 10.4 7.8 1.2 8.7 5.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CEP12546.1 - 3.3 7.5 6.1 12 5.8 4.2 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein EphA2_TM PF14575.1 CEP12547.1 - 0.00091 19.5 0.8 0.074 13.4 0.1 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 CEP12547.1 - 0.006 16.7 12.3 0.1 12.7 8.5 2.0 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2269 PF10027.4 CEP12547.1 - 0.0091 15.7 0.2 0.0091 15.7 0.2 1.6 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2269) Adeno_E3_CR2 PF02439.10 CEP12547.1 - 0.013 15.0 0.7 0.023 14.2 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 CEP12547.1 - 0.016 13.4 0.8 0.023 13.0 0.3 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.1 CEP12547.1 - 0.027 12.9 1.6 0.035 12.5 1.1 1.3 1 1 0 1 1 1 0 Amnionless TMEM154 PF15102.1 CEP12547.1 - 0.07 12.8 0.2 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family Trp_oprn_chp PF09534.5 CEP12547.1 - 0.1 12.1 0.8 0.12 12.0 0.0 1.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Plasmodium_Vir PF05795.6 CEP12547.1 - 0.37 9.9 2.5 0.18 11.0 0.2 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF1049 PF06305.6 CEP12547.1 - 0.76 9.3 5.4 0.8 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TMEM51 PF15345.1 CEP12547.1 - 5.1 6.7 11.4 0.24 11.0 3.3 2.0 1 1 0 1 1 1 0 Transmembrane protein 51 Sel1 PF08238.7 CEP12548.1 - 3.1e-24 84.8 4.2 1.1e-08 35.3 0.7 4.2 4 0 0 4 4 4 3 Sel1 repeat TPR_3 PF07720.7 CEP12548.1 - 0.0012 18.6 4.6 0.14 11.9 1.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP12548.1 - 0.067 12.8 1.7 0.85 9.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12548.1 - 0.97 9.5 0.0 0.97 9.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 CEP12549.1 - 4.7e-17 61.9 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12549.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP12549.1 - 0.015 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TPT PF03151.11 CEP12550.1 - 4.4e-27 94.6 9.0 5.2e-27 94.3 6.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.6 CEP12550.1 - 3.4e-07 29.4 8.1 3.9e-07 29.3 5.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP12550.1 - 3.5e-05 23.8 6.5 3.5e-05 23.8 4.5 1.6 1 1 0 2 2 2 1 EamA-like transporter family Cyt_c_ox_IV PF12270.3 CEP12550.1 - 0.12 12.1 4.1 0.73 9.5 0.4 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV HTH_23 PF13384.1 CEP12551.1 - 2.9e-08 33.1 0.0 1.5e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP12551.1 - 7.1e-06 25.9 0.1 4e-05 23.5 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP12551.1 - 1.9e-05 24.7 0.0 0.00015 21.8 0.0 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP12551.1 - 5.4e-05 23.9 0.0 0.0066 17.2 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 CEP12551.1 - 0.00087 19.2 0.1 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.1 CEP12551.1 - 0.0026 16.8 0.0 0.0056 15.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.1 CEP12551.1 - 0.0037 17.0 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 CEP12552.1 - 4.1e-20 72.0 0.0 5.7e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP12552.1 - 0.0005 20.1 0.0 0.001 19.1 0.0 1.5 1 1 1 2 2 2 1 Integrase core domain DDE_1 PF03184.14 CEP12552.1 - 0.11 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 CEP12552.1 - 0.11 11.2 0.0 0.13 10.9 0.0 1.3 1 1 0 1 1 1 0 Rhodopirellula transposase DDE domain HIT PF01230.18 CEP12552.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 HIT domain TRAPPC9-Trs120 PF08626.6 CEP12553.1 - 1.2e-188 628.9 5.7 1.5e-188 628.7 3.9 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_11 PF13414.1 CEP12553.1 - 0.0066 16.0 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CEP12553.1 - 0.019 14.5 0.1 0.05 13.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12553.1 - 0.032 14.1 0.1 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP12553.1 - 0.072 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP12553.1 - 0.083 12.7 0.1 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEP12553.1 - 0.12 13.0 0.0 0.52 11.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.27 CEP12554.1 - 5.9e-45 149.6 17.5 4.8e-09 35.7 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ATG16 PF08614.6 CEP12554.1 - 3.2e-38 131.5 32.8 3.2e-38 131.5 22.7 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) eIF2A PF08662.6 CEP12554.1 - 1.5e-10 41.1 0.1 0.013 15.1 0.0 3.8 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CEP12554.1 - 1.6e-08 33.2 7.9 0.032 12.3 0.2 5.1 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CEP12554.1 - 0.00024 19.5 0.2 0.0011 17.3 0.0 2.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 CEP12554.1 - 0.0026 17.2 2.0 0.087 12.2 1.3 3.2 1 1 0 1 1 1 1 PQQ-like domain H-kinase_dim PF02895.9 CEP12554.1 - 0.042 14.2 0.7 0.042 14.2 0.5 3.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain PD40 PF07676.7 CEP12554.1 - 0.14 11.8 0.1 14 5.4 0.1 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CENP-H PF05837.7 CEP12554.1 - 0.67 10.1 29.5 0.45 10.7 6.7 2.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.3 CEP12554.1 - 1.8 8.4 37.9 0.04 13.7 9.3 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Pyrophosphatase PF00719.14 CEP12555.1 - 1.4e-50 170.7 0.3 3.3e-50 169.5 0.3 1.5 2 0 0 2 2 2 1 Inorganic pyrophosphatase DUF814 PF05670.8 CEP12556.1 - 7.7e-09 35.3 0.1 6e-08 32.4 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF814) Flavi_NS5 PF00972.15 CEP12556.1 - 0.0065 14.4 0.7 0.0076 14.2 0.5 1.1 1 0 0 1 1 1 1 Flavivirus RNA-directed RNA polymerase DUF3211 PF11485.3 CEP12556.1 - 0.033 14.2 0.4 0.052 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) Nop25 PF09805.4 CEP12557.1 - 7.9e-21 74.5 21.4 1.1e-20 74.0 14.9 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) TarH PF02203.10 CEP12557.1 - 0.017 14.9 1.6 0.02 14.7 1.1 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue 6PF2K PF01591.13 CEP12559.1 - 6.6e-69 231.3 0.1 1e-68 230.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEP12559.1 - 7.3e-31 107.4 0.1 2.2e-30 105.8 0.0 1.8 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) BCDHK_Adom3 PF10436.4 CEP12560.1 - 7.5e-43 145.8 1.4 1.4e-42 144.9 0.9 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CEP12560.1 - 5.7e-16 58.2 0.0 1.4e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BAF1_ABF1 PF04684.8 CEP12560.1 - 0.00092 18.1 0.6 0.00092 18.1 0.4 1.6 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor HATPase_c_3 PF13589.1 CEP12560.1 - 0.0066 16.1 0.0 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SIT PF15330.1 CEP12561.1 - 0.13 12.3 0.2 0.59 10.3 0.0 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Thiolase_C PF02803.13 CEP12562.1 - 6.8e-10 38.4 0.0 9.7e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CEP12562.1 - 0.0029 16.6 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain MRG PF05712.8 CEP12563.1 - 8.2e-49 165.1 1.6 1.1e-48 164.7 1.1 1.2 1 0 0 1 1 1 1 MRG Glucan_synthase PF02364.10 CEP12563.1 - 0.076 10.8 0.3 0.38 8.5 0.0 1.7 1 1 1 2 2 2 0 1,3-beta-glucan synthase component Fumble PF03630.9 CEP12564.1 - 3.4e-120 400.9 1.3 1.3e-118 395.8 0.9 2.0 1 1 0 1 1 1 1 Fumble Tyr_Deacylase PF02580.11 CEP12564.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase Adaptin_N PF01602.15 CEP12565.1 - 3.4e-126 421.6 5.7 4.4e-126 421.2 4.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CEP12565.1 - 8.9e-31 106.1 0.0 3.3e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CEP12565.1 - 1.2e-14 54.5 0.0 2.9e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain FHA PF00498.21 CEP12566.1 - 3.5e-15 55.8 0.1 6.9e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CEP12566.1 - 4e-09 36.1 7.8 7e-09 35.3 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 CEP12566.1 - 1.9e-05 23.9 2.8 3.8e-05 23.0 2.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-rbx1 PF12678.2 CEP12566.1 - 0.00016 21.7 2.5 0.00042 20.3 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP12566.1 - 0.00038 20.0 7.4 0.00071 19.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP12566.1 - 0.0019 17.8 6.6 0.004 16.8 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP12566.1 - 0.0019 17.8 3.9 0.0035 16.9 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEP12566.1 - 0.0029 17.4 1.4 0.0063 16.3 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ycf1 PF05758.7 CEP12566.1 - 0.049 11.3 0.2 0.06 11.0 0.2 1.1 1 0 0 1 1 1 0 Ycf1 zf-C3HC4_2 PF13923.1 CEP12566.1 - 0.065 13.2 9.9 0.11 12.5 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CEP12566.1 - 0.14 11.8 2.8 0.28 10.8 2.0 1.5 1 0 0 1 1 1 0 PHD-finger OmpH PF03938.9 CEP12566.1 - 0.98 9.3 20.3 2.1 8.2 14.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ufd2P_core PF10408.4 CEP12566.1 - 1.6 6.8 7.1 2.4 6.2 4.9 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core SpoVR PF04293.8 CEP12566.1 - 3.2 6.0 8.4 4.9 5.4 5.8 1.1 1 0 0 1 1 1 0 SpoVR like protein Metallophos PF00149.23 CEP12567.1 - 1.2e-09 37.8 0.2 2.5e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP12567.1 - 9.6e-08 32.0 0.1 1.6e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1510 PF07423.6 CEP12567.1 - 0.00027 20.3 0.3 0.00042 19.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) COX6A PF02046.10 CEP12567.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa DUF3357 PF11837.3 CEP12567.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 CEP12567.1 - 0.024 15.0 0.1 0.07 13.5 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.4 CEP12567.1 - 0.041 13.6 0.0 0.084 12.6 0.0 1.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF929 PF06053.6 CEP12567.1 - 0.042 12.9 2.2 0.069 12.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) 7TM_GPCR_Str PF10326.4 CEP12567.1 - 0.058 12.5 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF1191 PF06697.7 CEP12567.1 - 0.066 12.0 0.3 0.1 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Orbi_NS3 PF01616.11 CEP12567.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 Sulfate_transp PF00916.15 CEP12568.1 - 2.8e-77 259.4 7.7 5.1e-77 258.6 5.4 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP12568.1 - 8.1e-32 108.7 2.3 8.1e-32 108.7 1.6 3.4 3 1 1 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEP12568.1 - 1.6e-06 27.4 0.0 3.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain DASH_Dad2 PF08654.5 CEP12569.1 - 0.14 12.1 0.1 0.23 11.4 0.1 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF1633 PF07794.6 CEP12569.1 - 2.5 5.9 6.9 2.7 5.8 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Asp PF00026.18 CEP12570.1 - 3e-112 374.9 0.0 3.6e-112 374.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP12570.1 - 3.4e-08 33.6 0.0 1.6e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP12570.1 - 9.6e-05 21.9 0.0 0.00035 20.1 0.0 2.0 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CEP12570.1 - 0.0058 17.1 0.0 2.2 8.8 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease Ribosomal_L6e PF01159.14 CEP12571.1 - 8e-36 122.5 0.1 8e-36 122.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 CEP12571.1 - 2.9e-09 36.6 1.2 2.9e-09 36.6 0.8 2.2 2 1 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Peptidase_C25_C PF03785.9 CEP12571.1 - 0.01 15.6 0.7 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain KOW PF00467.24 CEP12571.1 - 0.14 11.9 2.0 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 KOW motif DUF1900 PF08954.6 CEP12573.1 - 6.6e-54 181.1 0.0 2.2e-53 179.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CEP12573.1 - 5.2e-30 102.8 0.2 9.2e-30 102.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CEP12573.1 - 1.6e-25 88.0 0.4 5.1e-07 29.3 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ATG16 PF08614.6 CEP12573.1 - 0.022 14.5 7.5 0.036 13.8 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 CEP12573.1 - 0.057 13.2 11.8 0.089 12.6 8.2 1.3 1 0 0 1 1 1 0 Tropomyosin like IncA PF04156.9 CEP12573.1 - 0.65 9.5 9.3 0.93 9.0 6.4 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 CEP12573.1 - 0.73 10.2 6.1 1.2 9.4 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 CEP12573.1 - 8.3 6.2 9.4 2.5 7.8 0.3 3.4 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF4611 PF15387.1 CEP12574.1 - 1.5e-07 31.4 5.1 1.7e-07 31.3 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Gon7 PF08738.5 CEP12574.1 - 0.0004 20.3 4.0 0.0004 20.3 2.8 1.8 1 1 0 1 1 1 1 Gon7 family Acylphosphatase PF00708.13 CEP12574.1 - 0.04 14.0 0.5 0.049 13.7 0.3 1.4 1 0 0 1 1 1 0 Acylphosphatase Ribosomal_S17e PF00833.13 CEP12574.1 - 0.1 12.3 3.5 0.19 11.5 2.4 1.6 1 1 0 1 1 1 0 Ribosomal S17 OSTMP1 PF09777.4 CEP12574.1 - 0.13 11.4 1.1 0.14 11.2 0.8 1.0 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor KIP1 PF07765.7 CEP12574.1 - 0.64 9.8 3.7 2.3 8.1 0.1 2.2 1 1 1 2 2 2 0 KIP1-like protein DUF2935 PF11155.3 CEP12574.1 - 0.96 9.5 6.2 0.43 10.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) IncA PF04156.9 CEP12574.1 - 1.1 8.8 4.9 1.3 8.5 3.4 1.1 1 0 0 1 1 1 0 IncA protein RhoGAP PF00620.22 CEP12575.1 - 4e-47 159.6 0.1 7.3e-47 158.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 CEP12575.1 - 3.2e-15 56.2 0.1 1.2e-14 54.3 0.1 2.0 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 CEP12575.1 - 2e-14 52.8 0.2 4.4e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP12575.1 - 2.7e-14 52.2 0.9 7.4e-14 50.8 0.7 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP12575.1 - 2.8e-11 42.7 0.1 9.3e-11 41.0 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 CEP12575.1 - 5.6e-11 42.0 1.2 1.5e-10 40.7 0.8 1.8 1 0 0 1 1 1 1 WW domain PH_9 PF15410.1 CEP12575.1 - 1.6e-10 41.2 0.1 5.7e-10 39.3 0.0 2.0 1 1 1 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 CEP12575.1 - 0.0095 16.1 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1708 PF08101.6 CEP12575.1 - 0.14 10.9 4.1 0.11 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) Rax2 PF12768.2 CEP12576.1 - 7.9e-65 218.8 13.4 1.1e-46 159.2 0.0 6.2 4 1 0 5 5 5 5 Cortical protein marker for cell polarity SH3_9 PF14604.1 CEP12576.1 - 1.2e-06 27.9 0.1 2.4e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP12576.1 - 4.5e-05 22.7 0.1 8.6e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP12576.1 - 0.056 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain zf-C2H2_4 PF13894.1 CEP12577.1 - 0.00022 21.3 19.8 0.02 15.2 1.9 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP12577.1 - 0.00026 21.1 23.2 0.0022 18.2 1.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP12577.1 - 0.0009 19.4 3.7 0.0009 19.4 2.5 4.9 5 0 0 5 5 5 2 Zinc-finger double domain IncA PF04156.9 CEP12577.1 - 0.14 11.7 10.6 0.034 13.7 3.7 2.1 2 0 0 2 2 2 0 IncA protein zf-met PF12874.2 CEP12577.1 - 1.2 9.4 7.9 1.3 9.3 0.2 3.5 2 1 1 3 3 3 0 Zinc-finger of C2H2 type DUF605 PF04652.11 CEP12577.1 - 4 6.7 24.7 5.9 6.1 17.1 1.2 1 0 0 1 1 1 0 Vta1 like AAA_5 PF07728.9 CEP12578.1 - 1.1e-89 297.3 0.0 1.1e-34 119.1 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP12578.1 - 1.4e-07 31.7 3.3 0.061 13.3 0.1 4.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CEP12578.1 - 1.4e-05 25.2 2.1 0.067 13.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_3 PF07726.6 CEP12578.1 - 7e-05 22.4 0.0 1.9 8.1 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) CbbQ_C PF08406.5 CEP12578.1 - 9.7e-05 22.3 0.1 0.033 14.1 0.0 3.0 2 0 0 2 2 2 1 CbbQ/NirQ/NorQ C-terminal VWA_2 PF13519.1 CEP12578.1 - 0.00054 20.1 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA PF00004.24 CEP12578.1 - 0.0036 17.5 0.2 3.4 7.8 0.0 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEP12578.1 - 0.045 14.5 0.2 2.1 9.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain DUF4441 PF14536.1 CEP12578.1 - 0.064 13.2 0.5 0.25 11.3 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Mg_chelatase PF01078.16 CEP12578.1 - 0.076 12.1 0.6 6.9 5.7 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CEP12578.1 - 0.084 13.0 0.0 4.2 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase RabGAP-TBC PF00566.13 CEP12579.1 - 3.2e-49 167.3 0.1 3.2e-49 167.3 0.1 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Peptidase_M28 PF04389.12 CEP12581.1 - 7.8e-28 97.4 0.0 1.4e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 CEP12581.1 - 2e-07 30.0 0.1 8.3e-07 28.0 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase MS_channel PF00924.13 CEP12581.1 - 0.068 12.4 3.0 0.17 11.2 2.1 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel Ribosomal_L19 PF01245.15 CEP12582.1 - 1.7e-25 88.9 0.1 2.4e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 XG_FTase PF03254.8 CEP12583.1 - 1e-08 34.1 0.8 0.0018 16.8 0.0 2.5 3 0 0 3 3 3 2 Xyloglucan fucosyltransferase Pneumo_phosprot PF02478.11 CEP12583.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein HTH_29 PF13551.1 CEP12586.1 - 0.0043 17.1 0.0 0.0091 16.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DUF1439 PF07273.7 CEP12586.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) DDE_3 PF13358.1 CEP12586.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_28 PF13518.1 CEP12586.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.1 CEP12586.1 - 0.048 14.4 0.0 0.13 13.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_23 PF13384.1 CEP12586.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Cpn60_TCP1 PF00118.19 CEP12588.1 - 6e-143 476.9 10.0 6.8e-143 476.7 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 CEP12588.1 - 0.0031 17.5 0.4 0.051 13.6 0.0 3.1 4 0 0 4 4 4 1 Dinitrogenase iron-molybdenum cofactor Nfu_N PF08712.6 CEP12588.1 - 0.092 12.3 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal ATP_bind_4 PF01902.12 CEP12589.1 - 1.8e-36 125.5 0.0 4.8e-36 124.1 0.0 1.7 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 CEP12589.1 - 3.4e-28 97.8 0.0 7.8e-14 51.4 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP Erv26 PF04148.8 CEP12590.1 - 1.8e-60 203.9 21.3 3.6e-60 202.9 14.8 1.5 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 ATP-grasp PF02222.17 CEP12591.1 - 7.2e-66 220.7 0.1 1.4e-65 219.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.15 CEP12591.1 - 2.7e-62 208.4 3.8 6.8e-62 207.1 2.6 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp_4 PF13535.1 CEP12591.1 - 1.6e-14 54.0 0.1 3.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP12591.1 - 1.7e-07 30.3 0.1 2.1e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 CEP12591.1 - 5.8e-07 29.0 0.1 1e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 CEP12591.1 - 5.1e-06 26.0 0.1 7.2e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.14 CEP12591.1 - 1.7e-05 24.4 0.1 3.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 CEP12591.1 - 0.00049 19.3 0.2 0.0061 15.8 0.0 2.4 1 1 0 2 2 2 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 CEP12591.1 - 0.0038 16.4 0.1 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.9 CEP12591.1 - 0.0047 16.7 0.2 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain XdhC_C PF13478.1 CEP12591.1 - 0.0062 16.8 0.3 0.079 13.2 0.2 2.4 1 1 0 1 1 1 1 XdhC Rossmann domain 3HCDH_N PF02737.13 CEP12591.1 - 0.012 15.2 0.3 0.035 13.7 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CEP12591.1 - 0.025 14.4 0.1 0.087 12.6 0.0 2.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Clp1 PF06807.9 CEP12592.1 - 3.6e-39 134.5 0.0 5.3e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CEP12592.1 - 8e-16 58.0 0.0 2e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CEP12592.1 - 0.02 14.8 0.7 0.16 11.9 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase KaiC PF06745.8 CEP12592.1 - 0.026 13.6 0.1 0.56 9.2 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_35 PF14516.1 CEP12592.1 - 0.032 12.8 0.0 0.06 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 CEP12592.1 - 0.039 14.7 0.1 0.13 13.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEP12592.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEP12592.1 - 0.061 13.3 0.2 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 CEP12592.1 - 0.076 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CEP12592.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CEP12592.1 - 0.13 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PCI PF01399.22 CEP12593.1 - 4.7e-13 49.3 0.0 1.9e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain Apc3 PF12895.2 CEP12593.1 - 0.0022 18.1 2.6 0.032 14.3 0.4 2.8 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CEP12593.1 - 0.0094 15.8 0.2 4.3 7.3 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat ApoLp-III PF07464.6 CEP12593.1 - 0.074 13.0 0.2 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TPR_1 PF00515.23 CEP12593.1 - 0.091 12.4 0.5 6 6.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12593.1 - 0.14 12.1 4.0 1.1 9.3 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEP12593.1 - 0.16 12.7 0.1 7.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HECT PF00632.20 CEP12594.1 - 3.9e-96 321.9 0.1 5.9e-96 321.3 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CEP12594.1 - 1.7e-35 120.4 16.8 3.1e-12 46.1 0.3 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CEP12594.1 - 9.2e-12 44.6 0.7 2.3e-11 43.3 0.5 1.7 1 0 0 1 1 1 1 C2 domain DUF2169 PF09937.4 CEP12594.1 - 0.015 14.4 0.5 1.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2169) ubiquitin PF00240.18 CEP12596.1 - 3.3e-16 58.4 0.1 5.3e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CEP12596.1 - 1.2e-06 28.0 0.1 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEP12596.1 - 0.00081 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEP12596.1 - 0.0022 17.8 0.1 0.0047 16.7 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like bZIP_2 PF07716.10 CEP12598.1 - 6.5e-08 32.2 4.9 6.5e-08 32.2 3.4 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP12598.1 - 2.4e-07 30.6 8.1 3.9e-07 29.9 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor Cauli_AT PF03233.8 CEP12598.1 - 0.093 12.4 1.4 0.19 11.3 1.0 1.6 1 1 0 1 1 1 0 Aphid transmission protein bZIP_Maf PF03131.12 CEP12598.1 - 3.1 8.1 13.5 0.25 11.6 4.3 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor FYRC PF05965.9 CEP12599.1 - 3.8e-16 58.6 0.0 7.9e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 CEP12599.1 - 7.1e-13 47.7 0.3 1.3e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 F/Y-rich N-terminus TelA PF05816.6 CEP12599.1 - 0.028 13.1 2.5 0.041 12.5 1.7 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) ADIP PF11559.3 CEP12599.1 - 0.055 13.3 5.1 0.1 12.5 3.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Actin PF00022.14 CEP12602.1 - 7.4e-84 281.4 0.0 9.2e-84 281.1 0.0 1.0 1 0 0 1 1 1 1 Actin Asp PF00026.18 CEP12603.1 - 1.6e-38 132.7 1.2 4.4e-18 65.6 0.3 2.3 1 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP12603.1 - 5.4e-06 26.4 0.1 5.4e-06 26.4 0.1 2.3 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal MSP1_C PF07462.6 CEP12603.1 - 0.81 8.0 4.5 1.2 7.4 3.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SSP160 PF06933.6 CEP12603.1 - 7.6 4.3 19.2 12 3.7 13.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2887 PF11103.3 CEP12604.1 - 0.0014 18.2 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2887) RE_SinI PF09570.5 CEP12605.1 - 0.031 13.2 0.4 0.048 12.6 0.1 1.5 1 1 0 1 1 1 0 SinI restriction endonuclease Elongin_A PF06881.6 CEP12605.1 - 1.2 9.5 8.2 1.8 8.9 4.8 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A FAR1 PF03101.10 CEP12606.1 - 3.3e-08 33.9 2.2 5.3e-08 33.2 1.5 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain BrkDBD PF09607.5 CEP12606.1 - 0.1 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain Prefoldin PF02996.12 CEP12607.1 - 1.1e-32 112.1 2.8 1.9e-32 111.3 1.9 1.4 1 0 0 1 1 1 1 Prefoldin subunit Pol_alpha_B_N PF08418.5 CEP12607.1 - 0.02 14.4 0.4 0.03 13.8 0.0 1.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal CEP76-C2 PF15627.1 CEP12607.1 - 0.037 13.5 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain YqhG PF11079.3 CEP12607.1 - 0.037 12.8 0.1 0.087 11.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial protein YqhG of unknown function Syntaxin-6_N PF09177.6 CEP12607.1 - 0.12 12.8 1.7 2.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.15 CEP12607.1 - 0.15 11.8 5.6 2.1 8.1 0.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.4 CEP12607.1 - 0.16 12.1 5.1 3.2 7.9 0.1 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_assoc_C PF09821.4 CEP12607.1 - 0.16 12.2 3.5 7.3 6.8 0.2 2.8 2 1 2 4 4 4 0 C-terminal AAA-associated domain DUF2018 PF09442.5 CEP12607.1 - 0.18 12.4 2.3 1.2 9.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Mod_r PF07200.8 CEP12607.1 - 2.6 7.9 8.3 2 8.3 0.9 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MMgT PF10270.4 CEP12608.1 - 4.4e-20 72.0 0.2 5.8e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF4431 PF14485.1 CEP12608.1 - 0.032 13.8 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) AviRa PF11599.3 CEP12608.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 RRNA methyltransferase AviRa MOR2-PAG1_N PF14222.1 CEP12609.1 - 6.1e-140 467.5 2.5 3.6e-139 464.9 1.8 2.2 1 1 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.1 CEP12609.1 - 2.2e-69 234.2 16.6 3.6e-30 104.3 0.2 4.0 3 1 1 4 4 4 3 Cell morphogenesis central region MOR2-PAG1_C PF14225.1 CEP12609.1 - 6e-52 176.9 3.5 1.4e-51 175.7 1.0 2.8 2 0 0 2 2 2 1 Cell morphogenesis C-terminal FF PF01846.14 CEP12610.1 - 5.1e-40 135.2 7.4 1.5e-11 44.0 0.0 6.9 6 0 0 6 6 6 5 FF domain WW PF00397.21 CEP12610.1 - 3e-13 49.3 20.6 4e-08 32.9 4.8 2.8 2 0 0 2 2 2 2 WW domain Spore_II_R PF09551.5 CEP12610.1 - 0.11 12.5 1.9 0.62 10.0 1.3 2.3 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF2404 PF10296.4 CEP12611.1 - 6.8e-12 45.3 0.1 2.6e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Slu7 PF11708.3 CEP12612.1 - 3.5e-86 288.8 17.0 3.5e-86 288.8 11.8 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 CEP12612.1 - 0.046 13.3 0.7 0.11 12.1 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle SAP PF02037.22 CEP12613.1 - 1.9e-11 43.2 0.2 2.9e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 SAP domain Med12-LCEWAV PF12145.3 CEP12613.1 - 0.022 13.2 2.0 0.038 12.4 1.4 1.3 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain BPL_LplA_LipB PF03099.14 CEP12614.1 - 1.1e-14 54.5 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF1667 PF07892.6 CEP12614.1 - 0.093 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Cyto_heme_lyase PF01265.12 CEP12616.1 - 2.4e-73 246.9 9.6 1.2e-72 244.5 6.6 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Mso1_Sec1_bdg PF14475.1 CEP12616.1 - 0.083 12.3 0.4 2e+02 1.5 0.0 4.2 4 0 0 4 4 4 0 Sec1-binding region of Mso1 ChAPs PF09295.5 CEP12616.1 - 5.7 5.5 7.8 6.1 5.4 0.7 2.3 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) WH2 PF02205.15 CEP12617.1 - 2.6e-07 30.0 2.2 6.7e-07 28.7 0.9 2.2 2 0 0 2 2 2 1 WH2 motif UPF0121 PF03661.8 CEP12618.1 - 1.4e-17 63.7 3.2 1.7e-17 63.4 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TRAM_LAG1_CLN8 PF03798.11 CEP12619.1 - 1.9e-06 27.5 16.9 5.5e-06 26.0 11.8 1.6 1 1 0 1 1 1 1 TLC domain tRNA-synt_1b PF00579.20 CEP12620.1 - 4.8e-77 258.9 0.0 6.3e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 CEP12620.1 - 3e-06 26.5 0.0 5.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain RNB PF00773.14 CEP12621.1 - 2.2e-74 250.7 0.1 5.1e-74 249.4 0.1 1.7 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 CEP12621.1 - 0.0038 16.6 0.1 0.013 14.9 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease B OB domain Apc3 PF12895.2 CEP12621.1 - 0.044 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MCM PF00493.18 CEP12622.1 - 7.1e-125 416.1 2.9 1.1e-123 412.3 2.0 2.2 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CEP12622.1 - 1.1e-20 74.3 0.9 5.5e-20 72.0 0.0 2.6 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 CEP12622.1 - 3.5e-08 32.8 0.0 6e-07 28.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEP12622.1 - 0.0001 21.9 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEP12622.1 - 0.00078 19.1 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CEP12622.1 - 0.0014 18.1 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Glyco_hydro_31 PF01055.21 CEP12624.1 - 1.7e-149 498.4 10.9 2.4e-149 497.9 7.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CEP12624.1 - 1.1e-21 76.5 0.1 2.9e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Ribosomal_S17 PF00366.15 CEP12625.1 - 4e-23 81.2 2.6 4.6e-23 81.0 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Glutaredoxin PF00462.19 CEP12626.1 - 4.5e-32 109.8 0.0 2.4e-15 56.2 0.0 2.7 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 CEP12626.1 - 4.5e-20 71.2 0.0 1.3e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 CEP12626.1 - 1.5e-06 27.1 0.0 2.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Phosducin Thioredoxin_8 PF13905.1 CEP12626.1 - 4.1e-06 26.8 0.1 0.013 15.5 0.0 3.6 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CEP12626.1 - 0.00011 22.3 0.6 0.026 14.7 0.0 3.8 1 1 3 4 4 4 1 Thioredoxin-like domain SH3BGR PF04908.10 CEP12626.1 - 0.0058 16.5 0.0 2.8 7.9 0.0 2.7 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein ArsC PF03960.10 CEP12626.1 - 0.012 15.7 0.0 7.2 6.7 0.0 3.0 2 0 0 2 2 2 0 ArsC family TrbC_Ftype PF09673.5 CEP12626.1 - 0.034 13.7 0.0 0.22 11.1 0.0 2.3 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_7 PF13899.1 CEP12626.1 - 0.041 13.9 0.0 2.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin-like HyaE PF07449.6 CEP12626.1 - 0.06 13.2 0.0 0.83 9.5 0.0 2.8 5 0 0 5 5 5 0 Hydrogenase-1 expression protein HyaE zf-LITAF-like PF10601.4 CEP12627.1 - 1.3e-18 66.6 5.5 1.8e-18 66.1 3.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_CPXG PF14255.1 CEP12627.1 - 0.0019 17.9 0.9 0.047 13.5 0.1 2.3 2 0 0 2 2 2 1 Cysteine-rich CPXCG Zn-ribbon_8 PF09723.5 CEP12627.1 - 0.006 16.5 0.3 0.85 9.6 0.0 2.3 2 0 0 2 2 2 1 Zinc ribbon domain Sgf11 PF08209.6 CEP12627.1 - 0.0079 15.4 1.7 4.2 6.7 0.1 3.0 3 0 0 3 3 3 2 Sgf11 (transcriptional regulation protein) UPF0547 PF10571.4 CEP12627.1 - 0.043 13.5 1.8 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF164 PF02591.10 CEP12627.1 - 0.085 12.7 2.9 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-C2HC_2 PF13913.1 CEP12627.1 - 0.16 11.6 4.3 2.5 7.8 0.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn_Tnp_IS1 PF03811.8 CEP12627.1 - 0.22 11.0 3.8 7.1 6.2 0.2 2.4 2 0 0 2 2 2 0 InsA N-terminal domain DUF2396 PF09654.5 CEP12627.1 - 0.34 10.8 2.0 0.8 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) DZR PF12773.2 CEP12627.1 - 0.35 10.7 4.0 3 7.7 2.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.1 CEP12627.1 - 0.64 9.7 3.5 2.6 7.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CEP12627.1 - 0.72 9.4 3.6 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF4211 PF13926.1 CEP12628.1 - 1.1e-15 57.4 1.6 7.4e-15 54.6 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF3268 PF11672.3 CEP12628.1 - 0.11 12.6 0.7 0.25 11.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) Rhomboid PF01694.17 CEP12629.1 - 1.2e-34 119.4 12.4 1.2e-34 119.4 8.6 2.4 3 0 0 3 3 3 1 Rhomboid family Hexapep PF00132.19 CEP12630.1 - 1.2e-08 34.0 15.5 4e-05 22.9 1.8 4.1 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 CEP12630.1 - 0.39 9.2 2.7 3.4 6.1 0.0 2.1 1 1 0 2 2 2 0 L-fucokinase Hexapep_2 PF14602.1 CEP12630.1 - 5.9 6.5 17.3 3.8 7.1 1.7 3.2 1 1 3 4 4 4 0 Hexapeptide repeat of succinyl-transferase Rhomboid PF01694.17 CEP12631.1 - 5.4e-24 84.8 9.8 5.4e-24 84.8 6.8 1.6 1 1 1 2 2 2 1 Rhomboid family DUF1751 PF08551.5 CEP12631.1 - 0.001 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) MFS_1 PF07690.11 CEP12632.1 - 1.9e-37 128.8 26.7 2.8e-37 128.2 18.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP12632.1 - 7.2e-12 44.6 17.4 7.2e-12 44.6 12.1 1.8 1 1 1 2 2 2 2 Sugar (and other) transporter DSPc PF00782.15 CEP12633.1 - 3.2e-05 23.5 0.0 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP12633.1 - 5.6e-05 22.5 0.0 6.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Toxin_29 PF08116.6 CEP12634.1 - 2.8 7.8 11.2 0.52 10.1 4.0 2.2 1 1 1 2 2 2 0 PhTx neurotoxin family DUF606 PF04657.8 CEP12635.1 - 1.7e-31 109.1 12.9 2.2e-31 108.7 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF606 DUF4149 PF13664.1 CEP12635.1 - 0.012 15.6 7.0 0.14 12.2 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) E1-E2_ATPase PF00122.15 CEP12635.1 - 0.53 9.2 4.6 1.3 8.0 2.9 1.9 1 1 0 1 1 1 0 E1-E2 ATPase THOC7 PF05615.8 CEP12636.1 - 0.022 15.0 2.2 0.12 12.6 1.5 2.2 1 0 0 1 1 1 0 Tho complex subunit 7 p450 PF00067.17 CEP12637.1 - 4.3e-86 289.2 0.1 5.6e-86 288.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Phage-A118_gp45 PF10653.4 CEP12637.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 Col_cuticle_N PF01484.12 CEP12637.1 - 2.4 7.9 4.4 5.2 6.8 0.9 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain p450 PF00067.17 CEP12638.1 - 1.3e-76 258.0 0.0 1.7e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ETF PF01012.16 CEP12639.1 - 1.6e-38 131.9 6.0 3.1e-38 131.0 4.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 CEP12639.1 - 7.1e-37 124.9 1.9 9.3e-37 124.5 0.4 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain CW_binding_2 PF04122.7 CEP12639.1 - 0.12 12.6 1.2 13 6.0 0.0 2.8 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 PG_binding_3 PF09374.5 CEP12639.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain NTP_transf_2 PF01909.18 CEP12640.1 - 1.9e-05 24.8 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.6 CEP12640.1 - 0.048 13.5 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain PAP_central PF04928.12 CEP12640.1 - 0.055 12.2 0.2 0.37 9.5 0.0 2.2 2 1 0 2 2 2 0 Poly(A) polymerase central domain ThiF PF00899.16 CEP12642.1 - 1.5e-10 41.0 0.0 3.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 ThiF family Hexokinase_2 PF03727.11 CEP12643.1 - 1.4e-75 253.6 0.1 2.3e-75 252.9 0.1 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEP12643.1 - 1.2e-66 224.0 0.0 1.7e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase SurA_N_3 PF13624.1 CEP12643.1 - 0.077 12.9 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 SurA N-terminal domain Epimerase PF01370.16 CEP12644.1 - 6.9e-52 176.2 0.0 8.2e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CEP12644.1 - 3.1e-22 78.2 0.1 5.5e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CEP12644.1 - 1.4e-17 63.3 0.0 7e-17 61.0 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CEP12644.1 - 4e-14 52.2 0.1 7.2e-14 51.3 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CEP12644.1 - 5.2e-11 42.7 0.0 9.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CEP12644.1 - 1.3e-10 40.6 0.0 2.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CEP12644.1 - 1.7e-08 33.6 0.0 4.7e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CEP12644.1 - 2.6e-06 27.2 0.0 5.3e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEP12644.1 - 2.8e-06 27.4 0.0 6.4e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEP12644.1 - 0.0012 18.1 0.3 0.0034 16.6 0.2 1.8 2 1 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 CEP12644.1 - 0.042 13.2 0.1 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cys_Met_Meta_PP PF01053.15 CEP12644.1 - 0.059 11.6 0.0 0.096 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme 3HCDH_N PF02737.13 CEP12644.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 CEP12644.1 - 0.16 10.8 0.1 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase IBN_N PF03810.14 CEP12645.1 - 7.4e-13 48.2 1.1 3.8e-11 42.7 0.1 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CEP12645.1 - 1.5e-06 28.1 0.1 1.5e-06 28.1 0.1 4.3 4 2 1 5 5 5 1 Exportin 1-like protein DUF2435 PF10363.4 CEP12645.1 - 0.00052 19.8 0.4 0.0039 17.0 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT PF02985.17 CEP12645.1 - 0.012 15.6 0.1 0.1 12.7 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat Ycf1 PF05758.7 CEP12645.1 - 0.044 11.4 6.3 0.064 10.9 4.4 1.2 1 0 0 1 1 1 0 Ycf1 HEAT_2 PF13646.1 CEP12645.1 - 0.074 13.3 0.1 0.47 10.7 0.0 2.4 3 0 0 3 3 2 0 HEAT repeats HEAT_EZ PF13513.1 CEP12645.1 - 0.11 13.0 0.1 0.66 10.5 0.1 2.5 1 0 0 1 1 1 0 HEAT-like repeat Zip PF02535.17 CEP12645.1 - 0.18 10.7 0.4 0.36 9.7 0.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Adaptin_binding PF10199.4 CEP12645.1 - 0.58 10.4 18.2 1.7 8.9 12.6 1.7 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Spore_coat_CotO PF14153.1 CEP12645.1 - 1.8 7.9 15.8 3.2 7.1 11.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Sporozoite_P67 PF05642.6 CEP12645.1 - 3.5 5.3 6.2 6.3 4.5 4.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1510 PF07423.6 CEP12645.1 - 3.7 6.8 21.0 6.5 6.0 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 CEP12645.1 - 3.7 5.3 30.0 1.3 6.8 18.3 1.9 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 CEP12645.1 - 8.1 4.8 27.7 12 4.2 19.2 1.1 1 0 0 1 1 1 0 Daxx Family CAF-1_p150 PF11600.3 CEP12646.1 - 0.98 8.7 34.3 1.4 8.2 14.6 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIA PF03153.8 CEP12646.1 - 1.2 9.0 77.1 1.2 8.9 31.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_22 PF03901.12 CEP12647.1 - 5.4e-40 137.6 17.2 7.9e-40 137.1 11.9 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 CEP12647.1 - 0.0033 17.3 7.6 0.0033 17.3 5.3 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3291 PF11695.3 CEP12647.1 - 0.15 11.4 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) Cullin PF00888.17 CEP12648.1 - 1.7e-99 333.9 19.0 2e-99 333.7 13.2 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CEP12648.1 - 8.6e-21 73.5 0.2 3.3e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2779 PF11074.3 CEP12648.1 - 0.39 10.7 4.0 0.36 10.8 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) RVT_1 PF00078.22 CEP12650.1 - 3.2e-21 75.6 0.0 4.2e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GPP34 PF05719.6 CEP12651.1 - 5.6e-61 206.1 0.0 7.1e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PMT PF02366.13 CEP12652.1 - 1.3e-41 142.5 13.4 1.3e-41 142.5 9.3 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEP12652.1 - 2.9e-23 82.3 5.3 5.2e-23 81.5 3.7 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 CEP12652.1 - 0.00015 21.6 9.1 0.00015 21.6 6.3 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ERG2_Sigma1R PF04622.7 CEP12653.1 - 1.2e-77 260.0 0.8 1.4e-77 259.8 0.5 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ECH_C PF13766.1 CEP12655.1 - 4.6e-34 117.0 0.1 1.3e-33 115.6 0.0 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CEP12655.1 - 2e-29 102.4 0.0 7e-29 100.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3621 PF12285.3 CEP12656.1 - 0.13 12.3 2.1 0.51 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3621) N2227 PF07942.7 CEP12657.1 - 9.5e-107 355.9 0.1 1.3e-106 355.5 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.7 CEP12657.1 - 0.00025 21.4 0.0 0.0015 18.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP12657.1 - 0.0017 18.0 0.0 0.0048 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 CEP12658.1 - 1.6e-82 268.7 20.4 2.2e-12 46.3 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP12658.1 - 2.6e-09 35.7 7.6 0.16 10.0 0.1 5.2 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CEP12658.1 - 4.3e-09 35.6 3.5 0.029 13.1 0.1 4.9 3 1 2 5 5 5 3 Nup133 N terminal like LisH PF08513.6 CEP12658.1 - 0.0036 17.0 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 LisH Apc4_WD40 PF12894.2 CEP12658.1 - 0.017 14.6 0.0 0.065 12.7 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1830 PF08865.6 CEP12658.1 - 0.047 13.3 0.0 0.52 9.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1830) DUF1652 PF07865.6 CEP12658.1 - 0.048 13.2 0.0 20 4.8 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) PQQ_2 PF13360.1 CEP12658.1 - 0.061 12.7 0.2 6.2 6.1 0.0 2.7 1 1 0 2 2 2 0 PQQ-like domain Asp_protease_2 PF13650.1 CEP12660.1 - 1e-06 29.1 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF663 PF04950.7 CEP12660.1 - 0.02 13.9 2.5 0.036 13.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF663) RVP PF00077.15 CEP12660.1 - 0.089 12.7 0.0 0.58 10.1 0.0 2.3 1 1 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 CEP12661.1 - 8.2e-06 25.3 0.1 1.8e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) BOP1NT PF08145.7 CEP12662.1 - 4e-111 370.9 10.6 6.6e-111 370.1 7.3 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CEP12662.1 - 5.2e-32 108.5 8.5 2e-09 36.9 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat BUD22 PF09073.5 CEP12662.1 - 3.9 6.4 24.6 7.6 5.4 17.1 1.4 1 0 0 1 1 1 0 BUD22 Cyclin PF08613.6 CEP12663.1 - 1.5e-15 57.8 0.5 4.7e-15 56.2 0.4 1.9 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP12663.1 - 5.2e-07 29.2 0.5 1.7e-06 27.6 0.3 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zip PF02535.17 CEP12663.1 - 6.1 5.7 6.5 9.7 5.0 2.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter PTS_2-RNA PF01885.11 CEP12664.1 - 1.1e-52 178.0 0.0 1.4e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Sigma70_r1_2 PF00140.15 CEP12664.1 - 0.0058 16.2 0.1 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Peptidase_M28 PF04389.12 CEP12665.1 - 9.6e-33 113.4 0.1 2.7e-32 111.9 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 CEP12665.1 - 5.1e-06 26.1 0.0 8.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 CEP12665.1 - 0.003 16.8 0.0 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Nicastrin BRO1 PF03097.13 CEP12666.1 - 1.6e-77 260.8 0.0 1.6e-77 260.8 0.0 2.7 3 1 1 4 4 4 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CEP12666.1 - 1.2e-42 145.9 7.9 1.2e-42 145.9 5.5 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV HMG_box PF00505.14 CEP12666.1 - 1.1e-34 118.4 13.4 3.3e-20 72.1 0.7 3.6 4 0 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP12666.1 - 1e-24 86.6 3.8 1.1e-11 44.8 0.4 2.9 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.1 CEP12666.1 - 0.00013 21.6 4.2 0.00025 20.7 0.1 3.6 4 0 0 4 4 4 1 HMG (high mobility group) box 5 Pro_isomerase PF00160.16 CEP12667.1 - 1.3e-39 135.9 0.0 2.6e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CEP12667.1 - 1.7e-17 62.8 0.0 3.3e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12667.1 - 3.8e-14 52.4 0.0 9.3e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12667.1 - 5.9e-10 38.8 0.0 2e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3976 PF13121.1 CEP12668.1 - 0.08 12.8 3.2 0.17 11.7 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) zf-RVT PF13966.1 CEP12669.1 - 0.0001 22.5 1.1 0.00026 21.2 0.8 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CUE PF02845.11 CEP12670.1 - 4.4e-10 38.8 0.0 9.7e-10 37.7 0.0 1.6 1 0 0 1 1 1 1 CUE domain PTPLA PF04387.9 CEP12671.1 - 1.2e-48 164.6 15.0 1.2e-48 164.6 10.4 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA rve PF00665.21 CEP12673.1 - 1.1e-16 61.0 0.0 1.8e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP12673.1 - 0.004 16.5 0.1 0.007 15.7 0.1 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve PF00665.21 CEP12674.1 - 1.2e-08 35.1 0.0 3.7e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CEP12678.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) G_glu_transpept PF01019.16 CEP12679.1 - 0.12 10.8 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase zf-CCHC PF00098.18 CEP12682.1 - 0.00065 19.5 4.4 0.18 11.8 1.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP12682.1 - 0.81 9.3 3.0 1 9.0 1.3 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 CEP12682.1 - 1.6 8.2 4.5 19 4.8 1.0 2.4 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.21 CEP12683.1 - 5.2e-10 39.4 0.0 1e-08 35.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 CEP12684.1 - 1e-05 25.2 9.8 0.027 14.4 2.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP12684.1 - 0.02 14.3 5.6 0.02 14.3 3.9 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEP12684.1 - 0.14 11.8 0.2 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.1 CEP12687.1 - 7.3e-08 32.2 0.0 1.7e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease RVT_1 PF00078.22 CEP12688.1 - 0.078 12.3 0.8 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CEP12689.1 - 0.00052 20.0 1.0 0.0026 17.7 0.0 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CEP12690.1 - 6e-10 39.4 0.1 8.7e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP12690.1 - 1.4e-06 27.9 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CEP12690.1 - 5.1e-06 26.4 0.0 8.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CEP12690.1 - 5.7e-05 22.9 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CEP12690.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.7 CEP12690.1 - 0.013 15.0 0.1 0.056 12.9 0.0 1.9 1 1 1 2 2 2 0 Putative peptidase (DUF1758) Neur_chan_memb PF02932.11 CEP12691.1 - 2.1 8.1 5.3 2.9 7.7 3.7 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GCR1_C PF12550.3 CEP12693.1 - 2.7e-17 62.4 0.2 6.1e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF3971 PF13116.1 CEP12693.1 - 0.1 11.9 1.0 8.7 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function zf-CCHC_3 PF13917.1 CEP12695.1 - 0.026 14.2 0.2 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 CEP12695.1 - 0.035 14.0 1.6 0.055 13.4 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4187 PF13821.1 CEP12695.1 - 0.038 13.5 0.1 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RVT_1 PF00078.22 CEP12696.1 - 1.7e-11 43.8 0.2 3.7e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prenyltrans PF00432.16 CEP12697.1 - 2.5e-41 138.8 17.5 3e-09 36.2 0.0 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CEP12697.1 - 1.6e-24 86.4 0.5 5.5e-17 62.1 0.0 4.0 3 1 1 4 4 4 3 Prenyltransferase-like IPP-2 PF04979.9 CEP12697.1 - 8e-07 29.3 12.1 1.3e-05 25.4 8.4 2.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Prenyltrans_1 PF13243.1 CEP12697.1 - 1.5e-05 24.9 0.0 0.013 15.5 0.0 2.8 1 1 2 3 3 3 3 Prenyltransferase-like Nucleo_P87 PF07267.6 CEP12697.1 - 0.17 10.4 0.9 0.23 10.0 0.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 WD40 PF00400.27 CEP12698.1 - 1.2e-36 123.2 7.9 1.7e-07 30.8 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CEP12698.1 - 7.5e-31 105.8 0.3 1.5e-30 104.9 0.2 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 CEP12698.1 - 0.015 14.0 0.0 0.034 12.8 0.0 1.5 1 1 0 1 1 1 0 Nup133 N terminal like YscJ_FliF_C PF08345.6 CEP12699.1 - 0.08 12.9 0.2 0.091 12.7 0.2 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Ecl1 PF12855.2 CEP12701.1 - 3.3e-08 32.6 0.4 5.7e-08 31.9 0.3 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 CEP12701.1 - 0.0028 17.4 0.3 0.0068 16.2 0.2 1.7 1 0 0 1 1 1 1 MYND finger ANF_receptor PF01094.23 CEP12702.1 - 6.6e-28 97.4 6.5 8.4e-28 97.1 4.5 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 CEP12702.1 - 7.6e-14 51.6 13.3 1.5e-11 44.1 9.2 2.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.1 CEP12702.1 - 2.4e-08 33.7 1.6 6.8e-08 32.2 0.5 2.1 2 1 0 2 2 2 1 Periplasmic binding protein Acyl_transf_1 PF00698.16 CEP12703.1 - 2.1e-27 96.2 0.7 3.4e-27 95.6 0.5 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ribosomal_S4 PF00163.14 CEP12703.1 - 1.1e-13 51.4 3.6 2.3e-13 50.3 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CEP12703.1 - 1.2e-10 40.6 0.0 2.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain Paramyxo_NS_C PF02725.9 CEP12703.1 - 0.48 10.0 4.5 0.32 10.5 1.4 1.9 2 0 0 2 2 2 0 Non-structural protein C UvdE PF03851.9 CEP12704.1 - 1.1e-10 41.0 0.4 2.6e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 UV-endonuclease UvdE UvdE PF03851.9 CEP12705.1 - 1.3e-78 263.8 0.2 1.3e-78 263.8 0.1 2.3 2 1 0 2 2 2 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.19 CEP12705.1 - 0.00024 20.4 0.0 0.0007 18.9 0.0 1.7 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF1484 PF07363.6 CEP12705.1 - 0.32 11.3 5.7 0.77 10.1 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Tropomyosin_1 PF12718.2 CEP12706.1 - 2.3e-05 24.2 23.6 2.3e-05 24.2 16.4 2.9 1 1 1 2 2 2 1 Tropomyosin like CENP-F_leu_zip PF10473.4 CEP12706.1 - 0.0006 19.6 36.2 0.086 12.6 4.6 3.7 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cortex-I_coil PF09304.5 CEP12706.1 - 0.0028 17.6 30.7 0.81 9.7 3.9 4.0 2 2 1 3 3 3 3 Cortexillin I, coiled coil STAT_alpha PF01017.15 CEP12706.1 - 0.0031 17.2 9.6 0.031 14.0 0.7 2.4 2 1 0 2 2 2 2 STAT protein, all-alpha domain APG6 PF04111.7 CEP12706.1 - 0.0043 16.1 14.1 0.0043 16.1 9.8 3.0 1 1 2 3 3 3 2 Autophagy protein Apg6 AAA_13 PF13166.1 CEP12706.1 - 0.0045 15.5 16.3 0.0058 15.1 11.3 1.1 1 0 0 1 1 1 1 AAA domain CALCOCO1 PF07888.6 CEP12706.1 - 0.0071 14.6 32.8 0.055 11.7 12.0 2.6 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2968 PF11180.3 CEP12706.1 - 0.0099 15.2 15.3 0.22 10.8 0.6 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF2968) DUF972 PF06156.8 CEP12706.1 - 0.013 15.7 22.7 1.8 8.9 1.6 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 CEP12706.1 - 0.054 12.6 24.3 0.071 12.2 8.2 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 CEP12706.1 - 0.07 12.6 36.2 0.032 13.7 6.8 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 CEP12706.1 - 0.12 11.9 40.5 0.17 11.4 8.9 2.9 1 1 1 2 2 2 0 IncA protein DUF869 PF05911.6 CEP12706.1 - 0.18 10.0 23.0 0.24 9.5 15.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF342 PF03961.8 CEP12706.1 - 0.26 9.6 19.2 0.42 8.9 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF342) ORF6C PF10552.4 CEP12706.1 - 0.8 9.4 9.8 3.3 7.4 0.4 3.2 2 1 0 3 3 3 0 ORF6C domain Seryl_tRNA_N PF02403.17 CEP12706.1 - 0.9 9.5 24.3 0.044 13.7 1.1 3.8 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.3 CEP12706.1 - 1.4 8.1 14.7 2.6 7.2 0.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.1 CEP12706.1 - 3 7.8 39.2 0.91 9.4 6.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 CEP12706.1 - 4.1 7.2 8.2 4.9 6.9 0.3 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 CEP12706.1 - 4.4 6.9 14.3 2.9 7.5 3.4 3.1 1 1 3 4 4 4 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.6 CEP12706.1 - 5.8 7.3 20.6 3.1 8.2 2.9 4.0 1 1 3 4 4 4 0 Syntaxin 6, N-terminal OmpH PF03938.9 CEP12706.1 - 7.9 6.3 22.1 10 6.0 4.5 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HlyD PF00529.15 CEP12706.1 - 8.6 5.5 10.3 0.83 8.9 2.7 2.0 1 1 1 2 2 2 0 HlyD family secretion protein AATF-Che1 PF13339.1 CEP12706.1 - 8.7 6.5 15.0 1.2 9.2 1.6 3.1 1 1 1 3 3 3 0 Apoptosis antagonizing transcription factor TBPIP PF07106.8 CEP12706.1 - 9.1 5.7 23.6 0.69 9.4 2.7 3.2 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 CEP12706.1 - 9.2 6.0 31.2 6.3 6.6 2.0 5.2 3 2 2 5 5 5 0 Prefoldin subunit AAA_12 PF13087.1 CEP12707.1 - 8.1e-58 195.1 0.0 1.3e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEP12707.1 - 9.4e-41 139.9 0.8 1.2e-39 136.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CEP12707.1 - 5.8e-08 32.5 0.0 0.0039 16.7 0.0 2.7 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 CEP12707.1 - 5.6e-05 22.8 0.1 0.45 10.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain 4HB_MCP_1 PF12729.2 CEP12707.1 - 0.004 16.5 0.0 0.0095 15.3 0.0 1.6 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction UvrD_C_2 PF13538.1 CEP12707.1 - 0.0086 16.1 0.1 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 CEP12707.1 - 0.03 13.7 1.8 0.14 11.6 0.1 2.4 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain DEAD PF00270.24 CEP12707.1 - 0.089 12.2 0.3 0.21 11.0 0.1 1.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase zf-C5HC2 PF02928.11 CEP12709.1 - 0.00082 19.3 8.1 0.085 12.9 1.6 2.4 2 0 0 2 2 2 2 C5HC2 zinc finger Oxidored_molyb PF00174.14 CEP12711.1 - 3.1e-42 143.8 0.0 5.7e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CEP12711.1 - 4e-32 110.5 2.0 6.9e-32 109.8 1.4 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain ABC2_membrane PF01061.19 CEP12712.1 - 1.4e-86 288.9 64.9 1.2e-45 155.2 16.9 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CEP12712.1 - 6.4e-35 120.4 0.0 1.5e-18 67.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CEP12712.1 - 2.4e-25 88.1 0.0 3.6e-18 65.1 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 CEP12712.1 - 5.1e-14 52.0 42.8 4.5e-07 29.2 9.9 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 CEP12712.1 - 1.6e-10 40.8 0.0 3.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 CEP12712.1 - 5.7e-06 26.5 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CEP12712.1 - 9.1e-05 21.9 0.0 0.0049 16.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 CEP12712.1 - 0.00011 21.4 0.0 0.0033 16.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEP12712.1 - 0.0013 18.1 0.2 0.0057 16.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CEP12712.1 - 0.0017 18.4 0.2 0.18 11.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CEP12712.1 - 0.0024 17.4 0.9 1.2 8.8 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CEP12712.1 - 0.0098 15.7 0.0 0.53 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP12712.1 - 0.018 15.0 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 CEP12712.1 - 0.028 13.5 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 CEP12712.1 - 0.03 14.2 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 CEP12712.1 - 0.036 13.5 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CEP12712.1 - 0.041 13.3 0.4 5.9 6.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 CEP12712.1 - 0.082 12.5 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 CEP12712.1 - 0.1 13.4 0.1 0.8 10.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 CEP12712.1 - 0.12 12.0 1.1 2.7 7.8 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 CEP12712.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CEP12712.1 - 0.14 12.6 0.0 7.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 CEP12712.1 - 0.16 10.9 0.0 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 CEP12712.1 - 0.16 12.2 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain SCA7 PF08313.7 CEP12714.1 - 1.2e-26 92.1 0.4 1.2e-26 92.1 0.3 2.4 3 0 0 3 3 3 1 SCA7, zinc-binding domain Dsh_C PF12316.3 CEP12714.1 - 0.31 11.1 4.0 0.87 9.6 0.1 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Zip PF02535.17 CEP12714.1 - 0.43 9.5 2.5 0.6 9.0 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GATA PF00320.22 CEP12715.1 - 1.6e-15 56.1 3.4 4e-15 54.8 2.3 1.8 1 0 0 1 1 1 1 GATA zinc finger G-patch PF01585.18 CEP12716.1 - 5.7e-14 51.6 1.2 1e-13 50.8 0.8 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CEP12716.1 - 2.7e-05 23.9 0.4 2.7e-05 23.9 0.3 2.3 3 0 0 3 3 3 1 DExH-box splicing factor binding site E6 PF00518.12 CEP12716.1 - 0.018 15.3 0.1 0.038 14.3 0.1 1.5 1 0 0 1 1 1 0 Early Protein (E6) zf-met PF12874.2 CEP12718.1 - 0.0018 18.4 0.1 0.058 13.6 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF629 PF04780.7 CEP12718.1 - 0.028 12.9 0.3 0.29 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.3 CEP12718.1 - 0.029 14.5 0.0 0.077 13.1 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CEP12718.1 - 0.78 10.2 7.5 0.34 11.3 0.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger CUE PF02845.11 CEP12719.1 - 9e-07 28.2 0.2 1.6e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 CUE domain FUN14 PF04930.10 CEP12720.1 - 5.1e-25 87.6 1.9 6.7e-25 87.2 0.6 1.7 2 0 0 2 2 2 1 FUN14 family EF-hand_5 PF13202.1 CEP12720.1 - 0.0049 16.1 0.0 0.0099 15.1 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CEP12720.1 - 0.026 13.8 0.2 0.073 12.4 0.0 1.9 2 0 0 2 2 2 0 EF hand Pneumo_att_G PF05539.6 CEP12721.1 - 2.9 7.1 7.5 1.7 7.9 4.1 1.4 1 1 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DEAD PF00270.24 CEP12723.1 - 9.8e-37 126.0 0.0 2.3e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP12723.1 - 7.4e-27 93.0 0.0 6.6e-26 89.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP12723.1 - 0.0012 18.6 0.8 0.0028 17.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CEP12723.1 - 0.013 14.5 0.0 0.028 13.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DAO PF01266.19 CEP12724.1 - 3.2e-28 98.6 0.0 4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP12724.1 - 9.2e-05 21.4 0.0 0.00023 20.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CEP12724.1 - 0.0029 17.6 0.0 0.0055 16.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP12724.1 - 0.016 15.2 0.0 0.045 13.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP12724.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP12724.1 - 0.054 13.8 0.1 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEP12724.1 - 0.059 12.4 0.1 0.095 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 CEP12724.1 - 0.097 12.7 0.7 0.37 10.9 0.2 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 CEP12724.1 - 0.12 11.4 0.0 0.27 10.2 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trehalase PF01204.13 CEP12725.1 - 5.2e-179 596.1 3.1 6.4e-179 595.8 2.2 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CEP12725.1 - 4.8e-14 51.3 1.0 9.1e-14 50.4 0.7 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain YvbH_ext PF11724.3 CEP12725.1 - 0.041 13.5 0.0 2.7 7.7 0.0 3.1 3 0 0 3 3 3 0 YvbH-like oligomerisation region RPAP3_C PF13877.1 CEP12726.1 - 1.7e-22 79.1 0.0 3.5e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.1 CEP12726.1 - 7e-18 64.0 0.0 7.5e-11 41.5 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CEP12726.1 - 8.3e-14 50.3 0.3 3.1e-06 26.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP12726.1 - 2.3e-13 49.0 0.3 7.9e-05 22.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP12726.1 - 2.5e-09 36.2 0.4 0.00018 21.0 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP12726.1 - 1.3e-05 25.4 0.0 0.0038 17.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CEP12726.1 - 5.2e-05 23.0 0.0 0.00015 21.4 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEP12726.1 - 7.2e-05 23.0 0.0 0.26 11.6 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP12726.1 - 0.00014 21.7 0.1 0.39 11.0 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP12726.1 - 0.00058 20.4 0.1 0.031 14.9 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP12726.1 - 0.0082 16.0 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP12726.1 - 0.053 13.9 2.3 3.7 8.2 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP12726.1 - 0.1 12.4 0.0 5.8 6.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DDE_3 PF13358.1 CEP12727.1 - 1.7e-14 53.8 0.0 2.5e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Nucleoplasmin PF03066.10 CEP12731.1 - 0.77 9.2 7.0 1.4 8.4 4.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin FUSC_2 PF13515.1 CEP12732.1 - 6.3e-19 68.1 7.9 6.3e-19 68.1 5.5 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 CEP12732.1 - 5.7e-12 45.0 14.1 7e-11 41.4 3.2 2.7 2 1 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 CEP12732.1 - 1.3e-10 40.3 5.2 1.3e-10 40.3 3.6 2.6 3 0 0 3 3 3 2 Fusaric acid resistance protein family DUF2421 PF10334.4 CEP12732.1 - 2.3e-09 37.2 0.7 6.8e-09 35.6 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CEP12732.1 - 0.00059 18.7 0.8 0.00059 18.7 0.5 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2422) DUF939 PF06081.6 CEP12732.1 - 0.001 18.9 4.7 0.0034 17.2 3.3 2.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) SHR3_chaperone PF08229.6 CEP12733.1 - 1.9e-08 33.5 0.2 3.9e-06 25.9 0.1 2.0 2 0 0 2 2 2 2 ER membrane protein SH3 Glt_symporter PF03616.9 CEP12733.1 - 0.0033 15.9 0.1 0.0039 15.7 0.1 1.1 1 0 0 1 1 1 1 Sodium/glutamate symporter DUF2899 PF11449.3 CEP12733.1 - 0.0043 16.2 0.3 0.0068 15.6 0.1 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2899) DcuC PF03606.10 CEP12733.1 - 0.031 12.5 0.0 0.038 12.2 0.0 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF4366 PF14283.1 CEP12733.1 - 0.042 13.2 0.1 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4632 PF15451.1 CEP12733.1 - 3.8 7.5 5.8 7.2 6.6 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) FHIPEP PF00771.15 CEP12734.1 - 0.17 10.1 1.1 0.18 10.0 0.8 1.1 1 0 0 1 1 1 0 FHIPEP family HABP4_PAI-RBP1 PF04774.10 CEP12735.1 - 0.00051 20.5 0.2 0.00062 20.2 0.2 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Aa_trans PF01490.13 CEP12736.1 - 1.2e-37 129.4 23.2 3.7e-26 91.5 7.4 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Spore_permease PF03845.8 CEP12736.1 - 0.0026 16.4 17.3 0.0037 15.9 6.1 2.2 2 0 0 2 2 2 2 Spore germination protein HABP4_PAI-RBP1 PF04774.10 CEP12736.1 - 0.0027 18.2 0.1 0.0046 17.4 0.1 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family P5CR_dimer PF14748.1 CEP12736.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Daxx PF03344.10 CEP12738.1 - 0.0079 14.7 9.0 0.011 14.2 6.2 1.1 1 0 0 1 1 1 1 Daxx Family DUF2457 PF10446.4 CEP12738.1 - 0.37 9.4 13.7 0.58 8.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 CEP12738.1 - 0.71 7.7 17.3 1 7.2 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.10 CEP12738.1 - 3 7.0 10.9 4.6 6.4 7.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.6 CEP12738.1 - 4.9 4.8 12.9 7.8 4.2 8.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 CEP12738.1 - 5.1 6.2 13.7 7.2 5.7 9.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 CEP12738.1 - 8.8 4.2 10.0 12 3.7 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RPAP1_N PF08621.5 CEP12739.1 - 0.045 13.3 1.6 2.5 7.7 0.1 2.6 3 0 0 3 3 3 0 RPAP1-like, N-terminal MULE PF10551.4 CEP12740.1 - 5.1e-11 42.5 1.0 2.3e-10 40.4 0.3 2.4 1 1 1 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.12 CEP12740.1 - 0.0019 17.8 0.3 0.0019 17.8 0.2 2.7 1 1 0 2 2 2 1 Transposase FAR1 PF03101.10 CEP12740.1 - 0.0036 17.7 2.6 0.0053 17.2 0.7 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain CRAL_TRIO PF00650.15 CEP12740.1 - 0.018 14.5 1.2 0.1 12.0 0.1 2.4 2 0 0 2 2 2 0 CRAL/TRIO domain ALS2CR8 PF15299.1 CEP12740.1 - 0.023 14.2 3.1 0.066 12.7 2.1 1.8 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Filamin PF00630.14 CEP12740.1 - 0.032 14.7 0.3 2 9.0 0.1 2.4 2 0 0 2 2 2 0 Filamin/ABP280 repeat DDE_Tnp_IS240 PF13610.1 CEP12740.1 - 0.036 14.0 2.6 0.82 9.6 0.1 3.5 3 0 0 3 3 3 0 DDE domain Telomere_Sde2 PF13019.1 CEP12741.1 - 1.8e-36 125.2 0.8 4.2e-36 124.0 0.5 1.6 1 0 0 1 1 1 1 Telomere stability and silencing ubiquitin PF00240.18 CEP12741.1 - 0.0002 20.6 3.0 0.00028 20.2 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin family CAF1A PF12253.3 CEP12741.1 - 0.025 14.6 6.6 0.066 13.3 4.6 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A TBX PF12598.3 CEP12741.1 - 0.028 14.7 10.2 0.028 14.7 7.1 2.0 2 0 0 2 2 2 0 T-box transcription factor DUF3306 PF11748.3 CEP12742.1 - 0.11 13.1 3.5 0.27 11.8 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) CRAL_TRIO PF00650.15 CEP12743.1 - 1.1e-20 73.7 0.4 4.8e-19 68.3 0.1 2.3 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP12743.1 - 2.1e-12 46.9 0.3 5.4e-11 42.4 0.0 2.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEP12743.1 - 0.009 15.9 0.1 0.026 14.4 0.1 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain SPX PF03105.14 CEP12744.1 - 1.5e-40 139.7 6.4 2e-40 139.3 4.4 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CEP12744.1 - 3.3e-30 105.3 34.3 4.6e-30 104.9 23.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CEP12744.1 - 4e-07 28.9 18.6 4e-07 28.9 12.9 3.0 1 1 2 3 3 3 2 Citrate transporter AIG1 PF04548.11 CEP12745.1 - 1e-20 73.7 0.7 4.9e-20 71.5 0.4 2.1 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 CEP12745.1 - 9.7e-11 41.6 0.0 2.5e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEP12745.1 - 4e-07 29.9 0.5 0.014 15.2 0.2 2.4 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 CEP12745.1 - 5.7e-06 25.6 0.0 1.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CEP12745.1 - 0.00095 19.4 0.1 0.0025 18.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter GBP PF02263.14 CEP12745.1 - 0.0033 16.5 0.1 0.0086 15.1 0.0 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Miro PF08477.8 CEP12745.1 - 0.017 15.6 0.0 0.037 14.5 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein VirE PF05272.6 CEP12745.1 - 0.057 12.8 0.1 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Virulence-associated protein E FeoB_N PF02421.13 CEP12745.1 - 0.1 11.8 0.8 0.3 10.3 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_23 PF13476.1 CEP12745.1 - 0.14 12.4 2.2 0.37 11.1 1.5 1.9 1 1 0 1 1 1 0 AAA domain RVT_1 PF00078.22 CEP12746.1 - 2.6e-28 98.8 0.1 6.8e-28 97.4 0.0 1.8 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH PF00169.24 CEP12747.1 - 0.00027 21.0 6.6 0.0022 18.1 0.5 3.7 2 1 1 3 3 3 2 PH domain Peptidase_S24 PF00717.18 CEP12748.1 - 2.3e-10 39.9 0.0 4.4e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like ACT_3 PF10000.4 CEP12748.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 ACT domain Vac7 PF12751.2 CEP12749.1 - 1.4e-19 70.2 8.6 9.4e-15 54.3 0.1 2.4 1 1 1 2 2 2 2 Vacuolar segregation subunit 7 ADH_N PF08240.7 CEP12750.1 - 4e-26 90.9 4.8 6.5e-26 90.2 3.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP12750.1 - 3e-16 59.1 0.0 5.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP12750.1 - 0.0028 18.5 0.0 0.0049 17.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEP12750.1 - 0.0099 15.0 0.1 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-synt_D PF01813.12 CEP12751.1 - 2e-67 226.5 5.5 2.7e-67 226.1 3.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Allexi_40kDa PF05549.6 CEP12751.1 - 0.41 9.8 2.3 2.9 7.0 0.2 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.7 CEP12751.1 - 0.82 9.4 4.8 0.33 10.7 0.1 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Podoplanin PF05808.6 CEP12752.1 - 0.003 17.1 9.0 0.0033 16.9 5.2 1.8 1 1 1 2 2 2 1 Podoplanin Gly-zipper_Omp PF13488.1 CEP12752.1 - 0.0045 16.5 1.8 0.0074 15.8 1.2 1.2 1 0 0 1 1 1 1 Glycine zipper Beta-APP PF03494.8 CEP12752.1 - 0.047 13.1 3.1 0.11 11.9 2.1 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Nop14 PF04147.7 CEP12752.1 - 0.16 9.8 3.9 0.18 9.6 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 CEP12752.1 - 0.26 10.2 2.5 0.44 9.4 1.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Rick_17kDa_Anti PF05433.10 CEP12752.1 - 0.82 9.3 9.8 1.4 8.6 6.8 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain CDC45 PF02724.9 CEP12752.1 - 3.5 5.5 5.3 4.9 5.0 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SUR7 PF06687.7 CEP12753.1 - 0.19 11.2 16.8 4.5 6.7 11.7 2.2 1 1 0 1 1 1 0 SUR7/PalI family DUF2763 PF10961.3 CEP12753.1 - 0.42 11.0 2.2 2.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) PKD_channel PF08016.7 CEP12753.1 - 0.55 8.5 11.8 1.1 7.5 7.7 1.7 1 1 1 2 2 2 0 Polycystin cation channel Tetraspannin PF00335.15 CEP12753.1 - 0.79 8.9 22.3 0.036 13.3 8.6 2.3 1 1 1 2 2 2 0 Tetraspanin family DUF2754 PF10953.3 CEP12753.1 - 0.85 9.7 6.1 0.92 9.6 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2754) UPF0182 PF03699.8 CEP12753.1 - 3.5 5.4 14.2 0.66 7.8 7.0 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0182) PCI PF01399.22 CEP12754.1 - 6.9e-19 68.1 4.6 7.2e-19 68.0 0.1 3.1 2 1 0 2 2 2 1 PCI domain TPR_7 PF13176.1 CEP12754.1 - 0.0087 15.7 7.4 1.9 8.4 0.0 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat Rad33 PF08730.5 CEP12754.1 - 0.018 14.5 0.4 0.081 12.3 0.1 2.2 1 1 1 2 2 2 0 Rad33 TPR_11 PF13414.1 CEP12754.1 - 0.026 14.1 5.4 1.3 8.7 0.2 3.7 4 0 0 4 4 4 0 TPR repeat RPN7 PF10602.4 CEP12755.1 - 4.9e-60 201.9 1.0 7.6e-60 201.3 0.7 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CEP12755.1 - 1.8e-13 50.6 1.3 3.9e-13 49.6 0.1 2.3 4 0 0 4 4 3 1 PCI domain SAC3_GANP PF03399.11 CEP12755.1 - 0.00011 21.8 2.3 0.00022 20.8 1.6 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CEP12755.1 - 0.0011 18.6 0.7 0.022 14.5 0.1 2.3 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 HTH_DeoR PF08220.7 CEP12755.1 - 0.0021 17.5 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain TPR_8 PF13181.1 CEP12755.1 - 0.02 14.6 1.8 0.087 12.6 1.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12755.1 - 0.042 13.7 0.7 0.42 10.6 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.8 CEP12755.1 - 0.052 13.2 2.3 0.17 11.6 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF357) SpoIIID PF12116.3 CEP12755.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D TPR_6 PF13174.1 CEP12755.1 - 0.08 13.4 2.9 0.21 12.1 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TrmB PF01978.14 CEP12755.1 - 0.086 12.5 0.2 1.8 8.3 0.1 2.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Perilipin PF03036.11 CEP12756.1 - 5.5e-06 25.4 8.8 0.0049 15.7 0.0 2.3 1 1 1 2 2 2 2 Perilipin family RNase_E_G PF10150.4 CEP12756.1 - 0.011 14.9 0.9 0.019 14.2 0.7 1.5 1 0 0 1 1 1 0 Ribonuclease E/G family Prefoldin_3 PF13758.1 CEP12756.1 - 0.019 14.7 0.3 0.49 10.1 0.0 2.8 2 0 0 2 2 2 0 Prefoldin subunit PP2C_C PF07830.8 CEP12756.1 - 0.47 10.6 3.1 3.7 7.7 0.1 2.4 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain zf-C3HC4_3 PF13920.1 CEP12757.1 - 0.0003 20.4 7.3 0.0003 20.4 5.1 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 CEP12757.1 - 0.033 14.5 0.2 0.033 14.5 0.1 6.8 8 1 0 8 8 8 0 Zinc finger, C2H2 type YEATS PF03366.11 CEP12758.1 - 5.1e-18 64.5 0.3 9.9e-18 63.6 0.2 1.5 1 0 0 1 1 1 1 YEATS family BssC_TutF PF08201.6 CEP12758.1 - 0.11 12.0 0.1 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 BssC/TutF protein Nup54 PF13874.1 CEP12759.1 - 0.0072 16.0 8.3 0.0072 16.0 5.8 2.2 2 1 0 2 2 2 1 Nucleoporin complex subunit 54 Cyclase_polyket PF04673.7 CEP12759.1 - 0.019 14.9 0.5 0.055 13.5 0.4 1.8 1 1 0 1 1 1 0 Polyketide synthesis cyclase Nup88 PF10168.4 CEP12759.1 - 0.043 11.6 14.8 0.055 11.3 10.3 1.1 1 0 0 1 1 1 0 Nuclear pore component Baculo_PEP_C PF04513.7 CEP12759.1 - 0.058 13.2 1.9 15 5.4 0.0 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DELLA PF12041.3 CEP12759.1 - 0.085 12.5 0.0 0.26 10.9 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DUF1993 PF09351.5 CEP12759.1 - 0.23 11.3 8.2 0.41 10.5 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) FlaC_arch PF05377.6 CEP12759.1 - 0.5 10.3 3.0 13 5.8 0.2 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 CEP12759.1 - 0.57 9.9 7.6 0.41 10.4 0.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.9 CEP12759.1 - 0.75 9.7 14.5 0.074 12.9 6.9 1.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4460 PF14687.1 CEP12759.1 - 1.1 9.0 6.9 2 8.2 2.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4460) FliJ PF02050.11 CEP12759.1 - 2.6 8.1 17.1 0.34 10.9 0.3 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein Elongin_A PF06881.6 CEP12759.1 - 3.6 7.9 11.7 0.65 10.3 3.8 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A SlyX PF04102.7 CEP12759.1 - 3.9 7.9 13.1 1.4 9.3 0.7 4.2 3 1 2 5 5 4 0 SlyX Nup88 PF10168.4 CEP12760.1 - 9.9e-17 60.0 0.0 2.7e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore component Bestrophin PF01062.16 CEP12762.1 - 4.6e-63 212.8 1.7 9.7e-35 119.9 0.0 2.5 3 0 0 3 3 3 2 Bestrophin, RFP-TM, chloride channel DUF4239 PF14023.1 CEP12762.1 - 0.23 10.8 0.0 0.23 10.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) ApbA PF02558.11 CEP12763.1 - 1.3e-17 63.6 0.0 1.7e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CEP12763.1 - 2.8e-06 27.3 0.1 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FR47 PF08445.5 CEP12764.1 - 1.1e-08 34.7 0.0 9.2e-08 31.7 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 CEP12764.1 - 9.1e-05 22.5 0.1 0.00073 19.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP12764.1 - 0.00021 21.2 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP12764.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DnaJ PF00226.26 CEP12765.1 - 2.1e-27 94.6 1.2 3.5e-27 93.9 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CEP12765.1 - 4.8e-21 74.4 0.8 1.6e-16 59.9 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CEP12765.1 - 1.1e-13 51.0 20.3 1.8e-13 50.3 14.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CEP12765.1 - 0.071 12.8 14.3 0.062 12.9 1.8 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 CEP12765.1 - 0.95 8.9 13.5 9.1 5.8 0.8 4.2 3 1 1 4 4 4 0 A2L zinc ribbon domain SBF PF01758.11 CEP12766.1 - 1.6e-49 167.8 10.9 1.6e-49 167.8 7.6 3.1 3 0 0 3 3 3 1 Sodium Bile acid symporter family UPF0154 PF03672.8 CEP12766.1 - 0.046 13.3 1.4 0.22 11.1 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SPC12 PF06645.8 CEP12766.1 - 2.8 7.8 13.2 1.3 8.9 0.9 3.9 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RRM_1 PF00076.17 CEP12767.1 - 1.5e-19 69.4 0.1 2e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12767.1 - 8.2e-14 51.3 0.1 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12767.1 - 3.1e-08 33.3 0.0 4.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP12767.1 - 0.055 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3097 PF11296.3 CEP12767.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) PsbR PF04725.7 CEP12767.1 - 2.6 8.1 5.7 20 5.2 2.8 2.3 2 0 0 2 2 2 0 Photosystem II 10 kDa polypeptide PsbR ADH_N PF08240.7 CEP12769.1 - 1.2e-30 105.4 1.4 1.2e-30 105.4 1.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP12769.1 - 2.3e-22 78.9 0.6 3.4e-22 78.3 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP12769.1 - 0.0003 21.6 0.0 0.00064 20.6 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 CEP12769.1 - 0.0026 18.3 0.1 0.017 15.7 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 CEP12769.1 - 0.004 16.5 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1647 PF07801.6 CEP12769.1 - 0.0045 16.4 0.4 0.37 10.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1647) 3HCDH_N PF02737.13 CEP12769.1 - 0.0045 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTS PF05175.9 CEP12769.1 - 0.007 15.7 0.2 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Pyr_redox PF00070.22 CEP12769.1 - 0.024 15.0 0.1 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CEP12769.1 - 0.048 13.2 1.2 0.26 10.8 0.7 2.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 CEP12769.1 - 0.099 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 CEP12769.1 - 0.12 12.3 0.1 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_synthase PF02540.12 CEP12770.1 - 3.7e-23 81.7 0.0 8.2e-23 80.5 0.0 1.5 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 CEP12770.1 - 1.7e-07 30.7 0.0 2.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 CEP12770.1 - 0.004 16.6 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Pkinase PF00069.20 CEP12771.1 - 4.9e-66 222.5 0.0 6.5e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12771.1 - 1.7e-34 119.1 0.0 2.4e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP12771.1 - 7.1e-11 41.5 0.0 1.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP12771.1 - 0.0037 16.3 0.0 0.0064 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP12771.1 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CEP12771.1 - 0.023 13.4 1.4 0.056 12.2 0.1 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 CEP12771.1 - 0.043 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 KH_3 PF13014.1 CEP12772.1 - 3.7e-23 80.6 0.8 3e-07 29.9 0.1 6.3 7 0 0 7 7 7 4 KH domain KH_1 PF00013.24 CEP12772.1 - 3.5e-22 77.7 0.1 1.1e-09 37.8 0.0 6.3 6 0 0 6 6 6 5 KH domain HATPase_c_5 PF14501.1 CEP12772.1 - 0.044 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 GHKL domain Melibiase PF02065.13 CEP12773.1 - 3.5e-105 351.9 0.0 4.7e-105 351.5 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 CEP12773.1 - 8.6e-07 28.1 0.1 1.6e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 Glyco_hydro_31 PF01055.21 CEP12773.1 - 1.5e-05 23.9 0.0 2.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_97 PF10566.4 CEP12773.1 - 0.13 11.3 0.0 0.5 9.4 0.0 1.8 1 1 0 1 1 1 0 Glycoside hydrolase 97 Gti1_Pac2 PF09729.4 CEP12774.1 - 4.3e-31 108.0 0.0 4.3e-31 108.0 0.0 2.5 2 1 0 2 2 2 1 Gti1/Pac2 family PIF1 PF05970.9 CEP12775.1 - 1.3e-10 40.7 0.0 1.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP12775.1 - 7.3e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain HTH_psq PF05225.11 CEP12779.1 - 4.1e-07 29.4 0.0 1.5e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP12779.1 - 1.2e-06 28.4 0.9 1.8e-06 27.8 0.6 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.8 CEP12779.1 - 4.1e-05 22.8 0.0 8.4e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 CEP12779.1 - 0.00095 18.7 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP12779.1 - 0.0012 18.9 0.2 0.0016 18.5 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn helix FeoC PF09012.5 CEP12779.1 - 0.002 17.8 0.0 0.0037 16.9 0.0 1.5 1 1 0 1 1 1 1 FeoC like transcriptional regulator HTH_17 PF12728.2 CEP12779.1 - 0.014 15.6 0.1 0.031 14.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.11 CEP12779.1 - 0.014 15.0 0.2 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Transposase GntR PF00392.16 CEP12779.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_3 PF01381.17 CEP12779.1 - 0.017 14.9 0.1 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.11 CEP12779.1 - 0.019 14.2 0.2 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.14 CEP12779.1 - 0.042 13.5 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_37 PF13744.1 CEP12779.1 - 0.044 13.5 0.1 0.07 12.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 CEP12779.1 - 0.055 12.8 0.6 0.19 11.1 0.1 2.1 2 1 1 3 3 3 0 Winged helix-turn-helix DNA-binding PAX PF00292.13 CEP12779.1 - 0.07 12.8 0.1 0.093 12.4 0.0 1.3 1 1 0 1 1 1 0 'Paired box' domain Lzipper-MIP1 PF14389.1 CEP12779.1 - 0.14 12.2 0.9 0.3 11.2 0.1 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Spc97_Spc98 PF04130.8 CEP12780.1 - 1.9e-67 227.8 20.7 3.3e-67 227.0 14.3 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family N6_N4_Mtase PF01555.13 CEP12780.1 - 0.05 13.0 0.3 0.13 11.7 0.2 1.7 1 0 0 1 1 1 0 DNA methylase Pro_dh PF01619.13 CEP12781.1 - 5.2e-62 209.6 1.2 8.5e-62 208.9 0.9 1.3 1 0 0 1 1 1 1 Proline dehydrogenase Beta-Casp PF10996.3 CEP12784.1 - 1.1e-27 96.4 0.0 6.5e-27 93.9 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CEP12784.1 - 1.7e-15 57.2 0.1 4.1e-15 55.9 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CEP12784.1 - 8.2e-15 54.3 0.0 2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CEP12784.1 - 3.9e-12 46.1 0.2 5.6e-10 39.0 0.2 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEP12784.1 - 3.6e-06 26.7 0.0 1.4e-05 24.8 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain TIP120 PF08623.5 CEP12785.1 - 2.8e-63 212.5 4.3 2.4e-61 206.2 0.0 4.2 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 CEP12785.1 - 1.9e-17 63.3 15.0 2e-05 24.7 0.1 9.6 6 3 3 9 9 9 5 HEAT repeats HEAT_EZ PF13513.1 CEP12785.1 - 9e-11 41.9 26.8 0.36 11.3 0.2 11.6 12 2 1 13 13 13 4 HEAT-like repeat HEAT PF02985.17 CEP12785.1 - 9.1e-11 40.9 28.3 0.69 10.1 0.1 13.5 15 0 0 15 15 15 3 HEAT repeat Cnd1 PF12717.2 CEP12785.1 - 2.1e-06 27.6 27.8 0.042 13.6 1.4 7.3 6 2 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 CEP12785.1 - 6.8e-06 25.6 9.3 0.013 14.8 0.1 5.7 5 1 1 6 6 6 2 CLASP N terminal V-ATPase_H_C PF11698.3 CEP12785.1 - 0.00013 21.8 5.0 1.9 8.4 0.5 5.0 4 0 0 4 4 4 2 V-ATPase subunit H DUF1546 PF07571.8 CEP12785.1 - 0.00013 21.9 0.9 0.89 9.7 0.0 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF1546) Ipi1_N PF12333.3 CEP12785.1 - 0.032 14.1 8.2 21 5.1 0.0 6.6 5 3 2 7 7 7 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 CEP12785.1 - 6.2 6.8 11.5 52 3.8 0.0 6.5 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat FCH PF00611.18 CEP12786.1 - 3.3e-09 36.8 0.5 3.2e-08 33.6 0.3 2.7 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain FTCD_N PF07837.7 CEP12786.1 - 0.087 12.3 0.1 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Formiminotransferase domain, N-terminal subdomain KxDL PF10241.4 CEP12786.1 - 0.86 9.5 4.7 1.9 8.4 0.2 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein Sulfotransfer_3 PF13469.1 CEP12787.1 - 0.024 15.5 0.0 0.05 14.5 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family Aminotran_4 PF01063.14 CEP12788.1 - 2.7e-19 69.5 0.0 3.1e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DnaJ-X PF14308.1 CEP12789.1 - 8.4e-51 172.1 0.1 8.4e-51 172.1 0.1 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CEP12789.1 - 1.8e-25 88.4 0.4 3.9e-25 87.3 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain OmpH PF03938.9 CEP12789.1 - 6.7 6.6 8.7 2e+02 1.8 6.0 2.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Nucleos_tra2_C PF07662.8 CEP12790.1 - 2e-68 230.0 4.2 2e-68 230.0 2.9 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CEP12790.1 - 8.8e-18 64.4 4.9 8.8e-18 64.4 3.4 4.1 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus DUF1230 PF06799.6 CEP12790.1 - 4.3 7.1 7.2 0.57 10.0 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1230) Sec2p PF06428.6 CEP12791.1 - 1.3e-16 60.2 20.1 2.3e-15 56.2 8.1 2.5 1 1 1 2 2 2 2 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.14 CEP12791.1 - 3.6e-05 21.7 23.8 5.1e-05 21.2 16.5 1.1 1 0 0 1 1 1 1 Myosin tail Laminin_I PF06008.9 CEP12791.1 - 0.00073 18.9 10.9 0.0017 17.7 7.5 1.7 1 0 0 1 1 1 1 Laminin Domain I CALCOCO1 PF07888.6 CEP12791.1 - 0.0058 14.9 15.0 0.0093 14.3 10.4 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DNA_alkylation PF08713.6 CEP12791.1 - 0.02 14.4 0.8 0.033 13.6 0.0 1.7 2 0 0 2 2 2 0 DNA alkylation repair enzyme MAD PF05557.8 CEP12791.1 - 0.021 12.9 23.4 0.57 8.2 1.3 2.5 2 1 1 3 3 3 0 Mitotic checkpoint protein NPV_P10 PF05531.7 CEP12791.1 - 0.16 12.2 14.0 1.1 9.6 0.5 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 CEP12791.1 - 0.2 11.2 25.1 0.65 9.5 12.4 2.5 1 1 1 2 2 2 0 IncA protein DUF4250 PF14056.1 CEP12791.1 - 0.23 11.1 2.4 0.7 9.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) DUF948 PF06103.6 CEP12791.1 - 1.2 9.0 13.8 0.5 10.2 1.2 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.8 CEP12791.1 - 1.6 8.1 13.0 5.8 6.3 3.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Spc7 PF08317.6 CEP12791.1 - 2.1 6.9 24.8 0.66 8.5 9.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DASH_Hsk3 PF08227.6 CEP12791.1 - 2.9 8.1 6.9 4.9 7.4 0.2 2.7 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like ATG16 PF08614.6 CEP12791.1 - 6.1 6.6 25.6 0.85 9.4 11.1 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.1 CEP12791.1 - 6.6 5.8 24.8 8 5.5 2.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Glyco_tranf_2_3 PF13641.1 CEP12792.1 - 1.2e-22 80.8 0.0 1.8e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NIF PF03031.13 CEP12792.1 - 8.3e-22 77.5 0.7 1.6e-21 76.6 0.2 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Glycos_transf_2 PF00535.21 CEP12792.1 - 8e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP12792.1 - 3.2e-06 26.5 0.8 3.7e-05 23.0 0.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 CEP12792.1 - 6.8e-05 22.6 4.6 0.00019 21.2 3.2 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 CEP12792.1 - 0.058 11.7 0.2 0.14 10.4 0.0 1.7 2 1 0 2 2 2 0 Chitin synthase RVT_1 PF00078.22 CEP12794.1 - 5.1e-21 75.0 0.1 1.3e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP12794.1 - 6.5e-20 71.4 0.1 2.8e-19 69.3 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.19 CEP12794.1 - 4.9e-14 51.7 0.8 1e-13 50.7 0.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain OCIA PF07051.6 CEP12794.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) zf-H2C2 PF09337.5 CEP12794.1 - 0.011 15.0 0.1 0.032 13.6 0.1 1.8 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger RVP_2 PF08284.6 CEP12795.1 - 5.5e-05 23.1 0.1 0.00012 21.9 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEP12795.1 - 0.00056 20.3 0.1 0.0014 19.1 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP12795.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CEP12795.1 - 0.0023 17.3 0.0 0.0048 16.2 0.0 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Retrotrans_gag PF03732.12 CEP12796.1 - 7.8e-06 25.8 2.2 1.8e-05 24.6 0.0 2.7 4 0 0 4 4 4 1 Retrotransposon gag protein zf-C4pol PF14260.1 CEP12796.1 - 0.078 12.9 0.2 0.078 12.9 0.1 2.1 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta RP-C_C PF11800.3 CEP12796.1 - 0.34 10.5 8.7 0.47 10.1 1.9 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region DivIVA PF05103.8 CEP12796.1 - 3.7 7.6 7.4 1.1 9.3 1.0 2.3 2 0 0 2 2 2 0 DivIVA protein rve PF00665.21 CEP12797.1 - 1.3e-16 60.8 0.0 3.9e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP12797.1 - 0.0011 18.2 0.3 0.0051 16.2 0.2 2.2 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger DUF4514 PF14986.1 CEP12801.1 - 0.037 13.8 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) Retrotrans_gag PF03732.12 CEP12803.1 - 0.0047 16.9 0.1 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Ribosomal_L1 PF00687.16 CEP12806.1 - 9.8e-50 168.9 1.3 1.1e-49 168.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family CIAPIN1 PF05093.8 CEP12806.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Baculo_PEP_C PF04513.7 CEP12807.1 - 0.085 12.6 1.9 0.13 12.0 1.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Asp_protease_2 PF13650.1 CEP12808.1 - 0.0021 18.5 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP12808.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chromo PF00385.19 CEP12810.1 - 3.7e-07 29.7 1.3 8.8e-07 28.5 0.1 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP12810.1 - 0.076 12.7 1.1 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain NPV_P10 PF05531.7 CEP12810.1 - 0.084 13.1 0.4 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein rve PF00665.21 CEP12813.1 - 1.9e-15 57.0 0.0 3.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP12813.1 - 3.8e-10 39.2 0.2 1e-09 37.8 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PBP_dimer PF03717.10 CEP12813.1 - 0.023 14.7 0.5 0.051 13.6 0.0 1.7 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain Mito_fiss_reg PF05308.6 CEP12814.1 - 0.0025 17.2 17.2 0.0031 16.9 11.9 1.0 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF2681 PF10883.3 CEP12814.1 - 0.0098 16.0 29.0 0.0099 16.0 4.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) GCD14 PF08704.5 CEP12814.1 - 0.21 11.0 7.2 0.32 10.4 4.9 1.4 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Serinc PF03348.10 CEP12814.1 - 0.79 8.3 4.7 0.79 8.3 3.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Herpes_DNAp_acc PF04929.7 CEP12814.1 - 0.87 8.4 12.9 1 8.2 9.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Folate_carrier PF01770.13 CEP12814.1 - 0.99 7.8 5.4 1.2 7.5 3.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier DDHD PF02862.12 CEP12814.1 - 1 9.1 12.4 1.3 8.7 8.6 1.2 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.7 CEP12814.1 - 1.1 7.9 8.2 1.4 7.5 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.7 CEP12814.1 - 1.1 9.1 16.2 1.4 8.7 11.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1675 PF07897.6 CEP12814.1 - 1.1 9.0 9.6 1.3 8.8 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Activator_LAG-3 PF11498.3 CEP12814.1 - 1.2 7.7 25.9 1.6 7.4 17.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 LIM_bind PF01803.11 CEP12814.1 - 1.7 7.7 14.6 2.3 7.2 10.1 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Suf PF05843.9 CEP12814.1 - 2.1 8.0 16.3 2.6 7.7 11.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 CEP12814.1 - 3.5 7.4 12.5 4.5 7.0 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CEP12814.1 - 3.7 6.3 12.4 4.3 6.0 8.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein MRP-S25 PF13741.1 CEP12814.1 - 4.8 6.5 17.3 1.5 8.2 9.9 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S25 Band_3_cyto PF07565.8 CEP12814.1 - 9.6 5.6 15.0 12 5.3 10.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RVT_1 PF00078.22 CEP12815.1 - 8.3e-14 51.4 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Baculo_PEP_C PF04513.7 CEP12816.1 - 0.00033 20.4 0.9 0.00075 19.3 0.6 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CEP12816.1 - 0.0026 17.9 1.8 0.0065 16.6 0.7 2.1 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 CEP12816.1 - 0.0032 17.3 4.8 0.23 11.4 0.2 3.0 2 1 1 3 3 3 2 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 CEP12816.1 - 0.0057 16.4 1.7 0.2 11.4 0.7 2.4 2 0 0 2 2 2 1 Laminin Domain II Spc7 PF08317.6 CEP12816.1 - 0.018 13.6 1.0 0.044 12.4 0.3 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2046 PF09755.4 CEP12816.1 - 0.039 12.8 0.1 0.082 11.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF677 PF05055.7 CEP12816.1 - 0.04 12.5 0.5 0.061 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Apolipoprotein PF01442.13 CEP12816.1 - 0.062 12.7 0.1 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tweety PF04906.8 CEP12816.1 - 0.075 11.4 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 Tweety Katanin_con80 PF13925.1 CEP12816.1 - 0.12 12.1 0.6 2.6 7.7 0.1 2.5 2 1 1 3 3 3 0 con80 domain of Katanin LPP PF04728.8 CEP12816.1 - 0.14 11.9 6.0 1.4 8.7 1.2 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper ApoLp-III PF07464.6 CEP12816.1 - 0.16 11.9 0.9 0.33 10.9 0.6 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.4 CEP12816.1 - 0.17 12.0 0.8 0.6 10.2 0.3 2.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.16 CEP12816.1 - 1 8.8 5.4 3.3 7.1 2.9 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mononeg_RNA_pol PF00946.14 CEP12818.1 - 1.4e-90 304.2 5.8 2.5e-89 300.0 4.0 2.0 1 1 0 1 1 1 1 Mononegavirales RNA dependent RNA polymerase rve PF00665.21 CEP12819.1 - 3.2e-23 82.0 0.1 7.8e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP12819.1 - 0.001 18.4 0.2 0.0025 17.2 0.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 CEP12819.1 - 0.0013 18.1 0.1 0.0055 16.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain IncA PF04156.9 CEP12822.1 - 0.14 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 IncA protein PH PF00169.24 CEP12823.1 - 1.7e-08 34.5 0.2 1.1e-06 28.7 0.0 3.5 3 0 0 3 3 3 1 PH domain F-box-like PF12937.2 CEP12825.1 - 1.2e-08 34.5 0.0 2.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP12825.1 - 0.0005 19.6 0.1 0.0012 18.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain ABC_membrane_2 PF06472.10 CEP12827.1 - 7.1e-58 195.9 2.8 7.1e-58 195.9 1.9 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CEP12827.1 - 4.7e-19 69.0 0.0 8.7e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CEP12827.1 - 1.1e-05 25.5 0.1 3.8e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CEP12827.1 - 1.2e-05 24.6 0.1 0.095 11.9 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEP12827.1 - 0.0016 18.7 0.6 0.0059 16.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP12827.1 - 0.005 16.8 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CEP12827.1 - 0.011 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 CEP12827.1 - 0.017 14.7 0.0 0.085 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CEP12827.1 - 0.029 14.0 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 CEP12827.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CEP12827.1 - 0.057 14.2 0.0 0.21 12.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 CEP12827.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CEP12827.1 - 0.11 12.2 0.1 0.74 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 CEP12827.1 - 0.13 12.2 0.0 1 9.3 0.1 2.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DHDPS PF00701.17 CEP12828.1 - 2.4e-55 187.1 0.0 2.7e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Prenyltrans_2 PF13249.1 CEP12828.1 - 0.00039 20.7 0.0 0.00072 19.9 0.0 1.4 1 0 0 1 1 1 1 Prenyltransferase-like DUF4061 PF13270.1 CEP12829.1 - 0.18 11.9 1.1 0.46 10.6 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) Pheromone PF08015.6 CEP12829.1 - 1.1 10.1 5.0 3.1 8.7 3.5 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone WD40 PF00400.27 CEP12830.1 - 1.8e-52 173.3 19.7 1.3e-10 40.7 0.1 10.4 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 CEP12830.1 - 7.7e-25 86.9 0.0 1.2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nbas_N PF15492.1 CEP12830.1 - 0.0007 18.7 0.0 2.4 7.1 0.0 3.9 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 CEP12830.1 - 0.0016 17.3 0.3 3.2 6.4 0.0 3.8 5 0 0 5 5 5 2 Coatomer WD associated region PD40 PF07676.7 CEP12830.1 - 0.0017 17.9 0.0 0.071 12.8 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF3952 PF13130.1 CEP12830.1 - 0.072 13.0 0.2 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) FimP PF09766.4 CEP12831.1 - 1.9e-27 96.2 15.3 2.9e-27 95.6 10.6 1.3 1 0 0 1 1 1 1 Fms-interacting protein Thg1C PF14413.1 CEP12831.1 - 0.27 10.9 5.1 0.25 11.0 0.2 2.5 2 1 0 2 2 2 0 Thg1 C terminal domain Spc7 PF08317.6 CEP12832.1 - 1.3e-35 122.6 11.4 2.8e-35 121.5 7.9 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.1 CEP12832.1 - 7.4e-06 24.2 0.1 7.4e-06 24.2 0.0 2.4 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Prominin PF05478.6 CEP12832.1 - 0.36 8.3 9.8 0.06 10.8 4.3 1.4 2 0 0 2 2 2 0 Prominin Sulfate_transp PF00916.15 CEP12834.1 - 3.8e-65 219.6 10.5 3.8e-65 219.6 7.3 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP12834.1 - 2.8e-28 97.3 0.4 2.8e-28 97.3 0.3 3.6 2 1 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif G-patch_2 PF12656.2 CEP12834.1 - 7.3e-25 86.6 0.1 2.6e-24 84.8 0.1 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site STAS PF01740.16 CEP12834.1 - 5.6e-08 32.2 0.0 1.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CEP12834.1 - 0.00079 19.4 0.1 0.0019 18.2 0.1 1.6 1 0 0 1 1 1 1 STAS domain G-patch PF01585.18 CEP12834.1 - 0.00086 19.0 0.1 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 G-patch domain PAT1 PF09770.4 CEP12837.1 - 0.52 8.4 37.9 0.76 7.9 26.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CEP12837.1 - 4.3 5.6 11.8 6.1 5.1 8.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SNF2_N PF00176.18 CEP12838.1 - 1.7e-72 243.7 2.6 1.7e-72 243.7 1.8 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP12838.1 - 1.4e-16 60.1 0.0 4.8e-16 58.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 CEP12838.1 - 8.1e-09 35.1 5.2 8.1e-09 35.1 3.6 3.6 1 1 1 2 2 2 1 HSA DEAD PF00270.24 CEP12838.1 - 1.1e-05 25.0 0.0 5.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HLH PF00010.21 CEP12839.1 - 2.4e-11 43.1 0.3 4.7e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Dicty_REP PF05086.7 CEP12839.1 - 1 7.0 7.8 1.7 6.2 5.4 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF972 PF06156.8 CEP12839.1 - 2.8 8.3 6.3 6.3 7.2 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Ribosomal_L44 PF00935.14 CEP12841.1 - 4.9e-36 122.5 9.7 6.8e-36 122.1 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 CEP12841.1 - 2.2 8.6 8.4 2.4 8.4 1.0 2.8 2 1 0 2 2 2 0 Ribosomal protein L33 PseudoU_synth_2 PF00849.17 CEP12842.1 - 2.7e-26 92.3 0.0 4.8e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 CEP12842.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 S4 domain RRM_1 PF00076.17 CEP12843.1 - 1.7e-27 94.8 0.0 2.4e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12843.1 - 1.1e-17 63.6 0.0 1.3e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12843.1 - 0.0069 16.2 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Carboxyl_trans PF01039.17 CEP12844.1 - 3.9e-79 266.2 0.0 4.8e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Ku PF02735.11 CEP12846.1 - 1.1e-26 93.4 0.1 2e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CEP12846.1 - 6.4e-19 68.2 0.2 1.3e-18 67.2 0.2 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 CEP12846.1 - 3.5e-17 62.4 0.0 1.1e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Ku C terminal domain like A_deaminase PF00962.17 CEP12847.1 - 2.7e-114 381.5 0.0 3.5e-114 381.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-RVT PF13966.1 CEP12848.1 - 0.0079 16.4 0.3 0.015 15.5 0.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 CEP12849.1 - 2.8e-11 43.1 0.4 5.6e-11 42.2 0.3 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spc7_N PF15402.1 CEP12853.1 - 0.41 8.5 5.0 0.5 8.3 3.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RRM_6 PF14259.1 CEP12854.1 - 3.3e-32 110.2 1.2 7.6e-07 29.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP12854.1 - 4.6e-24 83.8 2.2 8.5e-08 31.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12854.1 - 3.3e-20 71.6 0.7 6.9e-05 22.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP12854.1 - 0.00014 21.6 0.4 0.02 14.7 0.1 2.9 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 CEP12854.1 - 0.0017 18.0 0.0 2 8.2 0.0 3.5 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF3808 PF10300.4 CEP12855.1 - 3.7e-66 223.5 2.6 1.6e-65 221.4 0.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) Sugar_tr PF00083.19 CEP12856.1 - 2.1e-71 240.8 17.1 2.4e-71 240.6 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP12856.1 - 2.8e-16 59.1 33.3 3.2e-08 32.6 1.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_Tnp_1_7 PF13843.1 CEP12858.1 - 7.1e-09 35.1 0.0 1.1e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Transposase IS4 DUF4509 PF14970.1 CEP12860.1 - 0.013 15.1 0.2 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) IncA PF04156.9 CEP12860.1 - 0.037 13.6 0.5 0.063 12.8 0.0 1.6 2 0 0 2 2 2 0 IncA protein TSC22 PF01166.13 CEP12861.1 - 9.4e-06 25.5 0.1 2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 CEP12861.1 - 0.0084 16.4 4.6 0.019 15.3 3.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF972) DUF904 PF06005.7 CEP12861.1 - 0.011 16.0 0.8 0.022 15.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF336 PF03928.9 CEP12861.1 - 0.018 14.8 1.4 0.03 14.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF336) HALZ PF02183.13 CEP12861.1 - 0.029 14.0 0.4 0.029 14.0 0.3 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 CEP12861.1 - 0.037 13.9 6.7 0.069 13.0 4.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 CEP12861.1 - 0.039 13.4 0.4 0.039 13.4 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator EzrA PF06160.7 CEP12861.1 - 0.08 11.1 2.5 0.11 10.6 1.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA bZIP_2 PF07716.10 CEP12861.1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Mito_fiss_reg PF05308.6 CEP12861.1 - 0.11 11.8 4.1 0.15 11.3 2.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CENP-H PF05837.7 CEP12861.1 - 0.22 11.6 3.4 0.24 11.6 1.4 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Mod_r PF07200.8 CEP12861.1 - 5.1 6.9 7.7 4.4 7.1 4.1 1.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein zf-H2C2 PF09337.5 CEP12862.1 - 0.042 13.2 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger PIF1 PF05970.9 CEP12863.1 - 8.2e-14 51.3 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 CEP12863.1 - 0.00053 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CEP12863.1 - 0.00055 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 CEP12863.1 - 0.024 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CEP12863.1 - 0.036 12.9 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 CEP12863.1 - 0.041 12.8 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MFS_1 PF07690.11 CEP12864.1 - 1.7e-38 132.2 24.4 2.1e-38 131.9 16.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MHC2-interact PF09307.5 CEP12864.1 - 0.19 11.4 0.5 5 6.9 0.0 2.8 3 0 0 3 3 3 0 CLIP, MHC2 interacting eRF1_2 PF03464.10 CEP12865.1 - 1.4e-42 145.1 0.1 2.5e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CEP12865.1 - 1.4e-36 125.2 0.0 2.6e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CEP12865.1 - 4.6e-26 90.9 0.0 7.8e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 CEP12865.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TPR_11 PF13414.1 CEP12866.1 - 8.6e-13 47.7 6.7 9.9e-10 37.9 1.6 2.2 1 1 0 2 2 2 2 TPR repeat Lactamase_B PF00753.22 CEP12866.1 - 6.4e-12 45.5 2.0 4.5e-11 42.7 1.4 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_1 PF00515.23 CEP12866.1 - 7.4e-08 31.6 4.7 0.011 15.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP12866.1 - 8.8e-08 31.5 5.0 0.021 14.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEP12866.1 - 1.5e-07 31.2 3.8 0.00039 20.3 1.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3856 PF12968.2 CEP12866.1 - 0.00037 20.3 2.3 0.012 15.4 1.6 2.2 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_16 PF13432.1 CEP12866.1 - 0.00092 19.8 3.3 0.081 13.6 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP12866.1 - 0.0026 17.4 1.9 0.65 9.9 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.2 CEP12866.1 - 0.0083 15.6 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_7 PF13176.1 CEP12866.1 - 0.011 15.5 0.3 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 CEP12866.1 - 0.092 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_19 PF14559.1 CEP12866.1 - 0.11 12.8 0.7 2.2 8.6 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CEP12866.1 - 0.34 11.0 2.2 0.69 10.0 1.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HEAT PF02985.17 CEP12868.1 - 2.4e-29 98.7 7.8 2.2e-05 24.1 0.1 10.8 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 CEP12868.1 - 4.1e-26 91.0 0.4 6.2e-08 32.8 0.1 7.1 5 2 2 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 CEP12868.1 - 3.9e-22 78.0 3.2 1.7e-06 28.3 0.0 10.9 9 3 6 15 15 15 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CEP12868.1 - 7.9e-15 55.0 0.1 0.001 19.3 0.0 6.6 6 1 1 7 7 6 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CEP12868.1 - 7.2e-11 41.8 0.1 0.01 15.1 0.0 6.0 5 2 2 7 7 7 3 CLASP N terminal IBN_N PF03810.14 CEP12868.1 - 1.7e-08 34.2 0.6 9e-08 31.9 0.2 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.2 CEP12868.1 - 9.7e-08 32.0 1.4 0.089 12.6 0.0 5.7 4 3 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CEP12868.1 - 1.1e-07 31.3 4.4 0.11 12.2 0.0 6.4 8 1 1 9 9 8 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CEP12868.1 - 3.7e-06 25.5 3.6 5.9e-05 21.5 0.1 4.1 3 3 1 4 4 4 1 Adaptin N terminal region Ipi1_N PF12333.3 CEP12868.1 - 4.7e-06 26.4 0.1 0.59 10.1 0.0 5.1 5 1 1 6 6 5 2 Rix1 complex component involved in 60S ribosome maturation DUF2454 PF10521.4 CEP12868.1 - 0.0011 18.0 2.6 0.005 15.8 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2454) MMS19_C PF12460.3 CEP12868.1 - 0.0023 16.7 4.2 0.15 10.7 0.0 4.4 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal DUF3730 PF12530.3 CEP12868.1 - 0.0043 17.0 5.2 5.1 6.9 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3730) CAS_CSE1 PF03378.10 CEP12868.1 - 0.04 12.2 0.1 0.04 12.2 0.1 3.5 4 1 1 5 5 5 0 CAS/CSE protein, C-terminus DUF2435 PF10363.4 CEP12868.1 - 0.044 13.6 0.0 8.1 6.4 0.0 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) UNC45-central PF11701.3 CEP12868.1 - 0.13 11.8 1.4 4.9 6.7 0.0 4.1 6 1 0 6 6 6 0 Myosin-binding striated muscle assembly central Proteasome PF00227.21 CEP12869.1 - 4.2e-61 205.5 0.2 6.1e-61 205.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEP12869.1 - 1.4e-11 43.4 0.3 3.5e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Robl_LC7 PF03259.12 CEP12869.1 - 0.13 11.8 0.1 0.28 10.7 0.1 1.6 1 0 0 1 1 1 0 Roadblock/LC7 domain RasGEF PF00617.14 CEP12870.1 - 3.8e-49 166.9 2.2 7e-49 166.1 1.5 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEP12870.1 - 1.8e-05 24.7 0.9 5.6e-05 23.1 0.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif MMR_HSR1 PF01926.18 CEP12870.1 - 0.039 13.8 0.2 0.18 11.8 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DGF-1_C PF11040.3 CEP12870.1 - 0.15 11.9 2.3 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus cNMP_binding PF00027.24 CEP12872.1 - 2.8e-40 136.0 0.0 5.3e-19 67.8 0.0 3.0 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 CEP12872.1 - 2.5e-20 70.2 15.5 0.071 13.2 0.0 10.8 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.2 CEP12872.1 - 5.2e-13 48.3 15.6 0.0023 17.4 0.7 6.8 5 2 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP12872.1 - 8.1e-10 37.3 20.5 1.9 8.8 0.0 10.9 10 2 2 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 CEP12872.1 - 4.8e-09 34.9 12.2 2.3 8.7 0.0 9.8 10 0 0 10 10 10 1 Leucine rich repeat LRR_8 PF13855.1 CEP12872.1 - 8.2e-07 28.6 23.8 0.0037 16.9 1.6 5.5 3 1 3 6 6 6 5 Leucine rich repeat F-box PF00646.28 CEP12872.1 - 7.2e-05 22.3 0.0 0.00036 20.1 0.0 2.2 1 0 0 1 1 1 1 F-box domain SAS4 PF15460.1 CEP12873.1 - 0.00031 20.5 16.1 0.0011 18.7 10.6 2.2 1 1 1 2 2 2 1 Something about silencing, SAS, complex subunit 4 Herpes_UL7 PF01677.11 CEP12873.1 - 0.22 10.8 1.2 1.8 7.8 0.5 2.0 2 0 0 2 2 2 0 Herpesvirus UL7 like DUF3154 PF11351.3 CEP12873.1 - 0.28 10.9 0.1 0.28 10.9 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) Med19 PF10278.4 CEP12873.1 - 0.55 9.8 11.9 0.014 15.0 2.6 2.0 1 1 1 2 2 2 0 Mediator of RNA pol II transcription subunit 19 RRM_1 PF00076.17 CEP12874.1 - 3.5e-26 90.6 3.3 4.6e-12 45.3 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12874.1 - 1.7e-19 69.5 0.3 4.5e-08 32.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12874.1 - 2.2e-19 69.0 1.1 3.6e-09 36.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP12874.1 - 1.1e-08 34.7 1.5 0.0081 15.9 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Ribosomal_S8 PF00410.14 CEP12874.1 - 0.024 14.4 0.3 0.95 9.3 0.1 2.4 1 1 1 2 2 2 0 Ribosomal protein S8 COQ9 PF08511.6 CEP12876.1 - 3.4e-12 45.6 0.2 6.7e-09 35.1 0.1 2.3 1 1 0 1 1 1 1 COQ9 RVT_1 PF00078.22 CEP12877.1 - 2.1e-29 102.3 0.1 4e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP12879.1 - 2.5e-06 27.8 0.0 3.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP12879.1 - 0.0053 16.5 0.0 0.0081 15.9 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2088 PF09861.4 CEP12879.1 - 0.096 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) RVP PF00077.15 CEP12879.1 - 0.1 12.5 0.1 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease PolyA_pol PF01743.15 CEP12881.1 - 3.5e-28 98.3 0.0 7.5e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CEP12881.1 - 8.8e-07 28.4 0.3 2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A CdhD PF03599.11 CEP12881.1 - 0.016 13.6 0.0 0.026 13.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Ribosomal_S13_N PF08069.7 CEP12882.1 - 5.7e-28 96.5 0.1 1.2e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CEP12882.1 - 1e-22 79.6 0.4 2.5e-22 78.4 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S15 TPT PF03151.11 CEP12883.1 - 7.8e-29 100.3 23.3 4.2e-28 97.9 7.4 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CEP12883.1 - 3.4e-14 52.4 23.0 5.1e-14 51.9 15.9 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP12883.1 - 1.6e-08 34.6 30.6 9.6e-05 22.4 5.1 2.9 1 1 2 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CEP12883.1 - 0.4 9.7 19.0 20 4.1 13.2 2.2 1 1 0 1 1 1 0 Nucleotide-sugar transporter EmrE PF13536.1 CEP12883.1 - 4.3 7.5 24.6 0.69 10.1 4.3 2.9 1 1 0 2 2 2 0 Multidrug resistance efflux transporter N6_Mtase PF02384.11 CEP12884.1 - 7.2e-16 58.1 0.0 2.9e-13 49.5 0.0 3.0 2 1 0 2 2 2 1 N-6 DNA Methylase Methyltransf_26 PF13659.1 CEP12884.1 - 1.2e-11 44.7 0.0 2.9e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Eco57I PF07669.6 CEP12884.1 - 5.8e-10 39.4 0.0 1.9e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 Eco57I restriction-modification methylase TaqI_C PF12950.2 CEP12884.1 - 0.00031 20.4 0.0 0.0011 18.7 0.0 2.0 1 0 0 1 1 1 1 TaqI-like C-terminal specificity domain UPF0020 PF01170.13 CEP12884.1 - 0.18 11.3 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 PAP_assoc PF03828.14 CEP12885.1 - 4e-18 65.1 0.1 1.1e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CEP12885.1 - 7.2e-05 23.0 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain TMEM171 PF15471.1 CEP12885.1 - 0.0071 15.1 0.4 0.012 14.4 0.3 1.3 1 0 0 1 1 1 1 Transmembrane protein family 171 OB_NTP_bind PF07717.11 CEP12886.1 - 2.4e-29 101.4 0.0 7.7e-29 99.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CEP12886.1 - 3.7e-27 94.3 0.1 3.7e-27 94.3 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEP12886.1 - 1e-11 44.5 0.0 3.5e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP12886.1 - 1.1e-08 34.7 0.1 2.1e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEP12886.1 - 8.6e-06 25.9 0.0 3.1e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CEP12886.1 - 0.0019 18.0 1.0 5.1 6.8 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SRP54 PF00448.17 CEP12886.1 - 0.002 17.6 0.1 0.0045 16.4 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain PhoH PF02562.11 CEP12886.1 - 0.0081 15.4 0.0 0.027 13.7 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 CEP12886.1 - 0.025 13.4 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 CEP12886.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEP12886.1 - 0.038 14.2 0.1 0.19 12.0 0.1 2.1 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CEP12886.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CEP12886.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pribosyltran PF00156.22 CEP12887.1 - 5.8e-15 55.1 0.2 8.7e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CEP12887.1 - 0.0056 15.9 0.1 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 CEP12887.1 - 0.031 13.6 0.1 0.05 12.9 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase HTH_Tnp_Tc3_2 PF01498.13 CEP12888.1 - 7.9e-10 38.6 0.2 1.4e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP12888.1 - 1.5e-05 25.0 0.1 0.00038 20.5 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP12888.1 - 0.0068 17.1 0.2 0.011 16.5 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 CEP12888.1 - 0.078 12.8 0.8 36 4.3 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Apolipoprotein PF01442.13 CEP12888.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CGGC PF08821.6 CEP12890.1 - 0.077 13.0 5.4 0.07 13.2 1.7 2.2 1 1 1 2 2 2 0 CGGC domain Ldh_1_N PF00056.18 CEP12891.1 - 7.7e-46 155.4 0.2 1.2e-45 154.8 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CEP12891.1 - 1.9e-44 151.4 0.0 2.8e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain THF_DHG_CYH_C PF02882.14 CEP12891.1 - 0.0099 14.9 1.2 0.097 11.7 0.1 2.5 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 CEP12891.1 - 0.011 16.0 0.2 0.086 13.1 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 CEP12891.1 - 0.014 14.7 2.3 1.5 8.1 0.0 2.6 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.14 CEP12891.1 - 0.034 12.8 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CEP12891.1 - 0.043 13.7 0.1 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.20 CEP12893.1 - 1.5e-41 142.2 0.3 1.4e-23 83.4 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP12893.1 - 7e-11 41.6 0.3 1.9e-06 27.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Dicty_REP PF05086.7 CEP12893.1 - 0.015 13.0 3.0 0.027 12.2 2.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pox_ser-thr_kin PF05445.6 CEP12893.1 - 0.047 12.4 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CEP12893.1 - 0.1 11.5 0.1 0.44 9.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Spt5_N PF11942.3 CEP12894.1 - 0.17 12.5 32.0 1.3 9.6 2.8 4.4 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal DUF3246 PF11596.3 CEP12894.1 - 3.2 6.9 9.9 2.3 7.4 1.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3246) Aa_trans PF01490.13 CEP12895.1 - 4.6e-54 183.4 33.5 1.5e-29 102.7 5.4 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CEP12895.1 - 0.00028 19.5 44.3 0.00099 17.7 30.7 1.8 1 1 0 1 1 1 1 Amino acid permease DUF1689 PF07954.6 CEP12895.1 - 0.054 13.3 0.4 0.054 13.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) F-box-like PF12937.2 CEP12896.1 - 5.9e-07 29.1 3.2 5.9e-07 29.1 2.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP12896.1 - 2.7e-06 26.8 4.0 8.9e-06 25.2 0.4 3.4 3 0 0 3 3 3 1 F-box domain ApoM PF11032.3 CEP12896.1 - 0.059 12.9 0.2 1 8.9 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein M (ApoM) RRM_6 PF14259.1 CEP12897.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 CEP12898.1 - 0.00093 18.9 0.9 0.003 17.3 0.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP12898.1 - 0.026 14.6 0.4 0.026 14.6 0.3 2.6 3 0 0 3 3 3 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP12898.1 - 0.042 13.5 2.7 0.1 12.2 0.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP12898.1 - 0.061 13.3 0.8 0.22 11.5 0.6 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP12898.1 - 0.41 10.4 5.0 0.094 12.4 0.5 2.2 2 0 0 2 2 2 0 zinc-RING finger domain ZapA PF05164.8 CEP12898.1 - 1.8 8.5 8.5 1.7 8.6 3.6 2.4 2 1 0 2 2 2 0 Cell division protein ZapA IMCp PF12314.3 CEP12899.1 - 0.035 14.2 1.3 0.44 10.7 0.1 2.2 1 1 1 2 2 2 0 Inner membrane complex protein ATP-synt_C PF00137.16 CEP12901.1 - 2.8e-30 103.9 31.2 1.3e-18 66.6 8.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 CEP12901.1 - 0.19 11.2 4.3 1.1 8.8 0.7 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DS PF01916.12 CEP12902.1 - 1.9e-139 463.9 0.0 2.2e-139 463.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase IFT20 PF14931.1 CEP12903.1 - 0.15 12.0 5.7 0.22 11.4 4.0 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF663 PF04950.7 CEP12903.1 - 0.21 10.4 3.6 0.26 10.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF663) DivIVA PF05103.8 CEP12903.1 - 2.3 8.2 8.2 2 8.4 4.4 1.7 1 1 1 2 2 2 0 DivIVA protein ubiquitin PF00240.18 CEP12904.1 - 1e-07 31.2 0.0 2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 CEP12904.1 - 6.7e-05 23.0 3.5 0.00013 22.1 2.4 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEP12904.1 - 0.00048 19.9 1.5 0.00086 19.1 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UPF0047 PF01894.12 CEP12905.1 - 8.1e-34 115.9 0.0 9.5e-34 115.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 HPP PF04982.8 CEP12906.1 - 1.3e-36 125.0 7.4 2.2e-36 124.3 5.1 1.4 1 0 0 1 1 1 1 HPP family DUF839 PF05787.8 CEP12906.1 - 0.073 12.0 0.1 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) PAP2 PF01569.16 CEP12906.1 - 0.32 10.6 4.5 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 PAP2 superfamily BAG PF02179.11 CEP12907.1 - 1.3e-10 41.1 0.4 1.3e-10 41.1 0.3 3.2 3 0 0 3 3 3 1 BAG domain rve PF00665.21 CEP12908.1 - 2.6e-10 40.4 0.0 4.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CEP12912.1 - 0.0011 18.7 2.6 0.0017 18.1 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEP12912.1 - 0.0045 17.0 0.1 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 CEP12915.1 - 9.1e-11 41.9 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CEP12916.1 - 4.9e-07 30.1 0.0 1.4e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CEP12916.1 - 0.00013 21.6 4.2 0.00033 20.4 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 CEP12916.1 - 0.00097 19.0 0.1 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CEP12916.1 - 0.0013 18.2 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Acetyltransf_4 PF13420.1 CEP12916.1 - 0.0014 18.5 1.1 0.023 14.6 0.1 3.1 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain gag-asp_proteas PF13975.1 CEP12916.1 - 0.0036 17.0 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2341 PF10102.4 CEP12916.1 - 0.055 13.6 0.3 0.16 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) RVP PF00077.15 CEP12916.1 - 0.057 13.3 0.1 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease UPF0278 PF08745.6 CEP12917.1 - 0.039 13.2 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 UPF0278 family HTH_psq PF05225.11 CEP12917.1 - 0.096 12.2 0.1 4.4 6.9 0.0 2.5 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP12917.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FixQ PF05545.6 CEP12918.1 - 0.14 11.7 2.1 0.36 10.4 1.5 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Chitin_synth_2 PF03142.10 CEP12919.1 - 1.1e-228 759.9 1.1 1.6e-228 759.3 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEP12919.1 - 2.2e-123 412.7 1.3 3e-123 412.3 0.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 CEP12919.1 - 1.1e-19 69.9 0.1 6.1e-14 51.5 0.1 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CEP12919.1 - 4.5e-14 52.8 0.0 3.2e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 CEP12919.1 - 1.1e-13 50.7 0.8 2.8e-13 49.4 0.6 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 CEP12919.1 - 2.2e-13 50.3 3.7 2.2e-13 50.3 2.6 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CEP12919.1 - 0.039 13.6 0.0 0.69 9.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Pentapeptide_4 PF13599.1 CEP12921.1 - 0.023 14.5 0.6 0.37 10.6 0.0 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) F-box-like PF12937.2 CEP12923.1 - 2.1e-07 30.5 0.0 6.8e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like Pentapeptide_4 PF13599.1 CEP12923.1 - 0.01 15.6 0.1 0.21 11.4 0.0 2.7 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Peptidase_M28 PF04389.12 CEP12925.1 - 2.5e-16 59.9 2.0 1.2e-15 57.7 0.1 2.5 2 1 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 CEP12925.1 - 5.1e-14 51.9 0.0 8.6e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CEP12925.1 - 0.00024 20.7 0.1 0.0005 19.7 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CEP12925.1 - 0.00085 18.8 0.0 0.0018 17.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 YchF-GTPase_C PF06071.8 CEP12926.1 - 2.5e-38 129.7 0.7 4.6e-38 128.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CEP12926.1 - 4.4e-18 65.3 0.0 1.2e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP12926.1 - 6.3e-08 32.0 0.0 1.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CEP12926.1 - 0.0048 16.7 0.2 0.93 9.2 0.1 2.4 1 1 1 2 2 2 2 Dynamin family PCI PF01399.22 CEP12927.1 - 1.8e-15 57.1 3.0 2.4e-15 56.7 0.4 2.4 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CEP12927.1 - 0.0082 15.9 0.2 0.027 14.2 0.1 1.9 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_14 PF13428.1 CEP12927.1 - 0.019 15.5 0.8 5.1 8.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 CEP12927.1 - 0.027 13.8 0.1 0.067 12.5 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 MethyTransf_Reg PF10119.4 CEP12927.1 - 0.06 13.8 0.3 0.26 11.8 0.0 2.2 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain TPR_11 PF13414.1 CEP12927.1 - 0.085 12.5 3.9 0.38 10.4 0.3 3.3 3 0 0 3 3 3 0 TPR repeat L27_2 PF09045.5 CEP12927.1 - 0.47 10.0 3.8 0.95 9.0 0.4 2.9 3 0 0 3 3 3 0 L27_2 DUF3384 PF11864.3 CEP12928.1 - 1e-54 185.7 0.4 1e-54 185.7 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 CEP12928.1 - 1.5e-53 181.0 0.0 3.1e-53 179.9 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 CEP12928.1 - 2.1e-34 119.1 1.7 2.1e-34 119.1 1.1 3.1 3 0 0 3 3 3 1 Tuberin MarC PF01914.12 CEP12928.1 - 0.041 13.0 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 MarC family integral membrane protein F-box-like PF12937.2 CEP12929.1 - 0.00011 21.7 0.1 0.00027 20.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP12929.1 - 0.028 14.0 0.1 0.15 11.7 0.0 2.3 3 0 0 3 3 3 0 F-box domain DUF3557 PF12078.3 CEP12929.1 - 0.067 12.9 1.4 1.2 8.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3557) FHA PF00498.21 CEP12931.1 - 1.8e-16 60.0 0.0 3.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Macoilin PF09726.4 CEP12931.1 - 2.5e-06 26.1 11.6 2.9e-06 25.8 8.0 1.1 1 0 0 1 1 1 1 Transmembrane protein APG17 PF04108.7 CEP12931.1 - 0.012 14.4 9.7 0.035 12.8 3.4 2.5 2 1 0 2 2 2 0 Autophagy protein Apg17 HOOK PF05622.7 CEP12931.1 - 0.014 13.2 11.2 0.02 12.7 7.8 1.1 1 0 0 1 1 1 0 HOOK protein CENP-F_leu_zip PF10473.4 CEP12931.1 - 0.031 14.1 18.5 0.084 12.7 10.5 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 CEP12931.1 - 0.06 13.3 12.0 1.6 8.7 0.3 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein Exonuc_VII_L PF02601.10 CEP12931.1 - 0.16 11.0 11.5 0.29 10.2 7.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lebercilin PF15619.1 CEP12931.1 - 0.43 9.9 20.3 0.48 9.8 12.6 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Snapin_Pallidin PF14712.1 CEP12931.1 - 0.85 9.9 11.0 0.3 11.3 4.1 2.3 1 1 1 2 2 2 0 Snapin/Pallidin YgaB PF14182.1 CEP12931.1 - 0.94 9.7 12.6 0.036 14.2 1.9 2.6 1 1 1 2 2 2 0 YgaB-like protein FlaC_arch PF05377.6 CEP12931.1 - 1.2 9.0 7.2 18 5.3 0.9 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 CEP12931.1 - 1.2 6.8 8.3 1.9 6.2 5.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.7 CEP12931.1 - 1.5 8.7 10.3 1.7 8.6 1.2 3.6 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat IncA PF04156.9 CEP12931.1 - 1.8 8.1 21.6 12 5.4 15.1 2.2 1 1 0 1 1 1 0 IncA protein Prefoldin PF02996.12 CEP12931.1 - 6.8 6.3 12.6 24 4.6 0.5 3.4 2 1 1 3 3 3 0 Prefoldin subunit Spc7 PF08317.6 CEP12931.1 - 8.3 4.9 20.8 5 5.7 9.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 CEP12931.1 - 9.4 6.7 12.9 68 3.9 1.2 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Methyltransf_11 PF08241.7 CEP12932.1 - 1.1e-14 54.6 0.0 2.2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP12932.1 - 3.8e-13 49.4 0.0 5.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP12932.1 - 2e-08 34.8 0.0 4.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP12932.1 - 2.1e-06 27.4 0.0 2.4e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP12932.1 - 5.4e-06 26.8 0.0 1.1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP12932.1 - 9.4e-06 24.8 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEP12932.1 - 0.00031 21.0 0.0 0.0073 16.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.11 CEP12932.1 - 0.00052 18.4 0.0 0.0007 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 CEP12932.1 - 0.0008 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 CEP12932.1 - 0.00087 18.6 0.0 0.0051 16.1 0.0 2.0 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.10 CEP12932.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 CEP12932.1 - 0.0018 17.6 0.0 0.0052 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CEP12932.1 - 0.0053 16.7 0.0 0.096 12.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 CEP12932.1 - 0.0098 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 CEP12932.1 - 0.01 14.7 0.0 0.021 13.7 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.14 CEP12932.1 - 0.034 14.1 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase CBFD_NFYB_HMF PF00808.18 CEP12933.1 - 5.5e-16 58.3 1.1 9.4e-16 57.6 0.8 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEP12933.1 - 1.6e-05 24.9 0.4 2.1e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3135 PF11333.3 CEP12933.1 - 0.2 11.8 0.8 3.3 7.9 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3135) ResIII PF04851.10 CEP12934.1 - 2.2e-17 63.4 0.9 1.6e-16 60.6 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEP12934.1 - 6.6e-12 45.1 0.0 2.8e-11 43.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BAG PF02179.11 CEP12934.1 - 1.1e-10 41.4 1.2 3.2e-10 39.9 0.8 1.8 1 0 0 1 1 1 1 BAG domain DEAD PF00270.24 CEP12934.1 - 8.8e-08 31.8 0.0 6.5e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 CEP12934.1 - 7.2e-05 21.9 0.0 0.00019 20.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NicO PF03824.11 CEP12935.1 - 1.5 8.0 4.8 2.6 7.2 3.3 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Beta_elim_lyase PF01212.16 CEP12937.1 - 3.1e-67 226.7 0.0 3.8e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CEP12937.1 - 2e-06 26.9 0.0 3.3e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CEP12937.1 - 0.013 13.8 0.0 0.02 13.2 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CEP12937.1 - 0.057 12.4 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PQ-loop PF04193.9 CEP12938.1 - 4.2e-37 125.5 13.9 6e-19 67.3 0.5 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 CEP12938.1 - 0.39 10.6 5.8 0.69 9.8 0.1 3.2 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Filament_head PF04732.9 CEP12939.1 - 0.3 11.8 5.5 0.36 11.5 3.8 1.1 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region Ribosomal_L29 PF00831.18 CEP12940.1 - 0.46 10.1 2.0 1.9 8.2 0.2 2.7 2 1 1 3 3 3 0 Ribosomal L29 protein Rad51 PF08423.6 CEP12943.1 - 7.5e-114 378.9 0.1 4.5e-98 327.2 0.0 2.1 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.1 CEP12943.1 - 8e-12 44.9 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CEP12943.1 - 2.2e-11 43.3 0.2 3e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CEP12943.1 - 2.1e-07 30.2 0.0 4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 CEP12943.1 - 1.9e-05 24.7 0.4 5.6e-05 23.2 0.3 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.1 CEP12943.1 - 0.004 16.7 0.1 0.026 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CEP12943.1 - 0.0058 16.8 0.1 0.026 14.7 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP12943.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_pol_A_CTD PF03118.10 CEP12943.1 - 0.028 13.8 0.1 0.066 12.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PTPLA PF04387.9 CEP12944.1 - 8.2e-51 171.6 14.2 1.2e-50 171.1 9.8 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2236 PF09995.4 CEP12946.1 - 1.4e-05 24.4 0.0 3.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) zf-CCCH PF00642.19 CEP12947.1 - 1e-19 69.7 20.2 2.2e-11 43.1 2.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CEP12947.1 - 6.1e-06 26.0 8.6 0.02 14.8 0.9 3.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type NTP_transferase PF00483.18 CEP12948.1 - 6.8e-13 48.4 0.0 1.5e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CEP12948.1 - 7.6e-10 39.0 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 CEP12948.1 - 6.3e-09 34.9 11.3 0.00036 19.9 2.4 3.7 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) KilA-N PF04383.8 CEP12951.1 - 0.001 18.6 1.9 0.0016 18.0 0.0 2.3 2 1 0 2 2 2 1 KilA-N domain IL3 PF02059.10 CEP12951.1 - 0.079 12.9 0.4 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Interleukin-3 Cu_amine_oxid PF01179.15 CEP12953.1 - 9.3e-68 228.8 0.0 1.4e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 CEP12953.1 - 1.7e-17 63.2 0.1 3.3e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 CEP12953.1 - 2.3e-11 43.5 0.0 4.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Inhibitor_I78 PF11720.3 CEP12954.1 - 4.7e-10 39.0 0.0 5.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 CEP12954.1 - 0.035 14.2 0.0 0.05 13.7 0.0 1.4 1 1 0 1 1 1 0 Potato inhibitor I family Ank_4 PF13637.1 CEP12955.1 - 1.6e-16 60.2 0.5 1.2e-10 41.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CEP12955.1 - 8.3e-15 53.7 0.3 1.3e-06 27.9 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 CEP12955.1 - 1e-14 54.6 6.6 1.2e-08 35.2 0.0 4.0 3 2 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP12955.1 - 4.5e-11 42.6 0.7 6.5e-05 23.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP12955.1 - 5.7e-11 41.5 0.6 1.9e-05 24.4 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 CEP12955.1 - 7.7e-05 22.2 0.0 0.00048 19.7 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain DUF2262 PF10020.4 CEP12955.1 - 1 9.5 8.8 3.6 7.7 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2262) CAP_N PF01213.14 CEP12955.1 - 1.6 7.9 10.8 0.44 9.7 1.4 2.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MBOAT_2 PF13813.1 CEP12956.1 - 8.8e-10 38.5 4.8 3.8e-05 23.6 0.0 3.1 4 0 0 4 4 4 2 Membrane bound O-acyl transferase family Ribosomal_60s PF00428.14 CEP12956.1 - 0.096 13.0 7.1 0.16 12.3 4.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med3 PF11593.3 CEP12956.1 - 0.17 11.0 10.6 0.24 10.6 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.12 CEP12956.1 - 0.78 9.5 17.8 1.4 8.7 12.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 CEP12956.1 - 5.1 4.7 6.3 6.8 4.3 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 CEP12956.1 - 9.7 4.0 14.9 15 3.4 10.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Aldose_epim PF01263.15 CEP12957.1 - 1.5e-85 286.9 0.1 1.7e-85 286.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2834 PF11196.3 CEP12958.1 - 0.0034 17.4 2.3 0.0034 17.4 1.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2834) Git3_C PF11970.3 CEP12958.1 - 0.047 13.4 2.4 0.83 9.4 0.0 3.2 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term UNC-50 PF05216.8 CEP12958.1 - 1 8.5 6.3 1.2 8.2 0.5 2.8 3 0 0 3 3 3 0 UNC-50 family Peptidase_A8 PF01252.13 CEP12959.1 - 0.2 11.2 6.4 0.069 12.7 1.6 2.3 3 0 0 3 3 3 0 Signal peptidase (SPase) II UBX PF00789.15 CEP12960.1 - 2.3e-16 59.6 0.0 5.2e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain MIP-T3 PF10243.4 CEP12960.1 - 0.00016 20.2 26.3 0.00024 19.6 18.2 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Thioredoxin_7 PF13899.1 CEP12960.1 - 0.14 12.1 0.8 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like AAR2 PF05282.6 CEP12960.1 - 0.16 10.8 9.0 0.32 9.8 6.3 1.6 1 0 0 1 1 1 0 AAR2 protein SH3BGR PF04908.10 CEP12960.1 - 0.33 10.9 0.1 0.33 10.9 0.0 3.3 2 1 1 3 3 3 0 SH3-binding, glutamic acid-rich protein Asp-B-Hydro_N PF05279.6 CEP12960.1 - 3.8 7.3 22.5 7.2 6.3 15.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_M24 PF00557.19 CEP12962.1 - 1.3e-40 139.2 0.0 2.3e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CEP12962.1 - 4.7e-23 82.1 0.0 1.3e-20 74.2 0.0 2.6 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain BCLP PF12304.3 CEP12962.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Beta-casein like protein Sds3 PF08598.6 CEP12963.1 - 6.6e-10 38.8 5.7 6.6e-10 38.8 3.9 2.9 2 1 2 4 4 4 1 Sds3-like GrpE PF01025.14 CEP12963.1 - 0.00046 19.7 1.1 0.00075 19.0 0.7 1.5 1 0 0 1 1 1 1 GrpE WBS_methylT PF12589.3 CEP12963.1 - 8.8 6.9 11.5 1.6 9.2 0.1 2.9 3 0 0 3 3 3 0 Methyltransferase involved in Williams-Beuren syndrome Cofilin_ADF PF00241.15 CEP12964.1 - 1.5e-30 105.7 2.8 3e-30 104.7 1.9 1.5 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3987 PF13148.1 CEP12964.1 - 0.022 13.3 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) zf-CCHC_3 PF13917.1 CEP12965.1 - 3.6e-08 33.0 0.6 1e-07 31.5 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF572 PF04502.8 CEP12965.1 - 0.45 9.6 26.0 0.56 9.3 18.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Proteasome PF00227.21 CEP12966.1 - 3.4e-55 186.3 0.1 4.7e-55 185.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEP12966.1 - 1.9e-15 55.8 0.1 3.3e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RRM_1 PF00076.17 CEP12968.1 - 2.2e-17 62.4 0.1 3.6e-08 32.9 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP12968.1 - 1.2e-13 50.8 0.0 3.4e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP12968.1 - 1.2e-06 28.1 0.0 2.1e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3987 PF13148.1 CEP12968.1 - 0.058 11.9 0.3 0.14 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Nop16 PF09420.5 CEP12969.1 - 7.3e-49 166.0 10.5 1.1e-48 165.4 7.3 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Cation_efflux PF01545.16 CEP12970.1 - 1.5e-45 155.4 7.4 2e-45 155.1 5.1 1.1 1 0 0 1 1 1 1 Cation efflux family GCR1_C PF12550.3 CEP12970.1 - 0.00031 20.5 0.2 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Sulfate_transp PF00916.15 CEP12971.1 - 4.4e-52 176.8 8.0 4.4e-52 176.8 5.5 2.0 2 1 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP12971.1 - 3.5e-24 84.2 2.9 3.5e-24 84.2 2.0 2.9 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEP12971.1 - 4.5e-24 84.1 0.0 7.7e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CEP12971.1 - 0.0018 18.2 0.0 0.0073 16.3 0.0 2.0 2 0 0 2 2 2 1 STAS domain WD40 PF00400.27 CEP12972.1 - 5.8e-57 187.6 9.9 1.2e-08 34.4 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CEP12972.1 - 8.9e-10 37.3 13.1 0.024 12.7 0.1 5.8 2 1 3 5 5 5 4 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP12972.1 - 8.2e-09 35.0 0.1 1.6e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.1 CEP12972.1 - 2.2e-07 30.6 0.2 0.087 12.6 0.0 5.1 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 CEP12972.1 - 4.1e-05 23.1 1.0 0.39 10.1 0.4 3.3 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 CEP12972.1 - 0.0001 22.4 1.9 13 6.2 0.0 5.2 5 0 0 5 5 5 0 PQQ-like domain Nucleoporin_N PF08801.6 CEP12972.1 - 0.00073 18.3 1.8 3.2 6.4 0.0 3.8 2 1 2 4 4 4 2 Nup133 N terminal like F-box PF00646.28 CEP12972.1 - 0.0029 17.2 1.2 0.0081 15.8 0.1 2.2 2 0 0 2 2 2 1 F-box domain eIF2A PF08662.6 CEP12972.1 - 0.0056 16.4 0.0 2.6 7.7 0.0 3.0 1 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A CNH PF00780.17 CEP12972.1 - 0.026 13.9 0.1 25 4.1 0.0 4.0 5 0 0 5 5 5 0 CNH domain YopR_core PF09025.5 CEP12972.1 - 0.065 13.2 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 YopR Core MraZ PF02381.13 CEP12972.1 - 0.13 12.0 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 MraZ protein PilO PF04350.8 CEP12972.1 - 0.14 12.0 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO SNARE PF05739.14 CEP12973.1 - 6.2e-18 64.2 11.3 3.5e-17 61.8 5.2 2.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CEP12973.1 - 3.8e-13 49.4 6.4 3.8e-13 49.4 4.4 3.0 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 CEP12973.1 - 0.00095 19.1 11.0 0.00095 19.1 7.6 2.7 2 0 0 2 2 2 1 Syntaxin-like protein DUF4094 PF13334.1 CEP12973.1 - 0.019 15.3 2.2 0.019 15.3 1.5 3.7 2 2 2 4 4 4 0 Domain of unknown function (DUF4094) DctQ PF04290.7 CEP12973.1 - 0.03 14.1 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component MCPsignal PF00015.16 CEP12973.1 - 0.032 13.7 27.2 0.016 14.7 5.3 2.9 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FANCI_HD1 PF14679.1 CEP12973.1 - 0.037 13.7 0.3 0.12 12.1 0.2 1.9 1 0 0 1 1 1 0 FANCI helical domain 1 Spectrin PF00435.16 CEP12973.1 - 0.11 12.8 10.2 1.8 8.8 0.2 2.9 2 2 0 2 2 2 0 Spectrin repeat Vac_Fusion PF02346.11 CEP12973.1 - 0.11 11.9 4.6 0.16 11.3 0.1 3.0 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Lipase_GDSL PF00657.17 CEP12973.1 - 0.13 12.0 5.4 0.15 11.8 2.8 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF3708 PF12501.3 CEP12973.1 - 4.5 7.0 6.3 2.9 7.6 0.6 2.7 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter GP41 PF00517.12 CEP12973.1 - 9.2 5.7 17.9 12 5.4 2.6 3.4 2 2 0 2 2 2 0 Retroviral envelope protein F-box PF00646.28 CEP12974.1 - 0.016 14.8 1.0 0.07 12.8 0.7 2.2 1 0 0 1 1 1 0 F-box domain DUF1829 PF08862.5 CEP12974.1 - 0.12 12.6 0.5 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF1829 APG12 PF04110.8 CEP12975.1 - 2e-33 114.3 0.0 3.3e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 CEP12975.1 - 0.00081 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like GAD-like PF08887.6 CEP12975.1 - 0.032 14.3 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 GAD-like domain Retrotrans_gag PF03732.12 CEP12976.1 - 0.42 10.7 7.0 1.7 8.7 0.6 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Chitin_synth_2 PF03142.10 CEP12977.1 - 3.3e-216 718.7 0.1 4.7e-216 718.2 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 CEP12977.1 - 2.1e-15 57.1 0.0 1.7e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEP12977.1 - 1.4e-14 54.2 3.8 1.4e-14 54.2 2.6 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 CEP12977.1 - 2.4e-06 27.2 0.0 5.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 CEP12977.1 - 7.9e-06 25.2 0.1 0.00013 21.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CEP12977.1 - 0.0014 18.3 0.0 0.087 12.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 PK PF00224.16 CEP12978.1 - 1.7e-165 549.8 2.6 2.1e-165 549.4 1.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CEP12978.1 - 4.5e-30 103.6 0.0 9.8e-30 102.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CEP12978.1 - 0.00014 20.7 0.4 0.00045 19.1 0.3 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 CEP12978.1 - 0.0058 15.5 0.1 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain CNF1 PF05785.7 CEP12978.1 - 0.036 12.9 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor Cellulase PF00150.13 CEP12978.1 - 0.07 12.3 0.1 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Mg_trans_NIPA PF05653.9 CEP12979.1 - 5.3e-61 206.1 12.9 1.1e-57 195.2 9.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CEP12979.1 - 3.6e-06 27.1 0.3 3.6e-06 27.1 0.2 3.3 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 CEP12979.1 - 7.8e-05 22.7 0.9 7.8e-05 22.7 0.6 4.0 3 1 1 4 4 4 1 EamA-like transporter family Git3_C PF11970.3 CEP12979.1 - 0.13 12.0 0.8 0.34 10.6 0.6 1.6 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term IL22 PF14565.1 CEP12980.1 - 0.11 12.5 0.2 0.53 10.3 0.0 1.9 1 1 1 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Elongin_A PF06881.6 CEP12980.1 - 0.24 11.7 6.7 1.5 9.2 3.3 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CDC45 PF02724.9 CEP12980.1 - 0.4 8.6 6.0 0.41 8.6 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2730 PF10805.3 CEP12981.1 - 0.049 13.3 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) MT-A70 PF05063.9 CEP12982.1 - 1.1e-12 47.8 0.3 2.5e-12 46.6 0.2 1.6 1 0 0 1 1 1 1 MT-A70 Methyltransf_21 PF05050.7 CEP12982.1 - 7e-11 42.3 0.0 8.4e-10 38.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain PAP2_3 PF14378.1 CEP12982.1 - 0.14 11.6 0.7 0.26 10.7 0.5 1.3 1 0 0 1 1 1 0 PAP2 superfamily TraV PF09676.5 CEP12982.1 - 0.46 11.1 5.3 0.6 10.8 0.4 2.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) COG2 PF06148.6 CEP12983.1 - 2.3e-23 82.5 1.1 2.3e-23 82.5 0.8 3.3 3 1 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 CEP12983.1 - 1.1e-18 67.4 0.6 1.1e-18 67.4 0.4 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 CEP12983.1 - 2.1e-07 30.6 0.8 1.8e-06 27.6 0.1 3.0 2 0 0 2 2 2 1 Vps51/Vps67 TcdA_TcdB PF12919.2 CEP12983.1 - 0.0034 15.9 0.9 0.0034 15.9 0.6 3.7 3 1 1 4 4 4 1 TcdA/TcdB catalytic glycosyltransferase domain Baculo_PEP_C PF04513.7 CEP12983.1 - 0.0055 16.5 22.1 0.02 14.7 0.8 4.9 6 0 0 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus KIP1 PF07765.7 CEP12983.1 - 0.01 15.6 0.0 0.32 10.8 0.1 3.4 3 0 0 3 3 3 0 KIP1-like protein FlaC_arch PF05377.6 CEP12983.1 - 0.045 13.6 0.3 0.045 13.6 0.2 3.6 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) FliJ PF02050.11 CEP12983.1 - 0.19 11.7 2.4 0.19 11.7 0.1 2.1 2 0 0 2 2 1 0 Flagellar FliJ protein Med4 PF10018.4 CEP12983.1 - 0.4 10.0 3.5 0.2 11.0 0.6 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2743 PF10899.3 CEP12983.1 - 0.94 8.8 5.8 0.16 11.3 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2743) BUD22 PF09073.5 CEP12983.1 - 1.6 7.6 8.2 5.2 6.0 0.3 2.5 2 1 0 2 2 2 0 BUD22 Reo_sigmaC PF04582.7 CEP12983.1 - 4.2 6.4 10.7 1 8.4 0.6 2.6 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 CEP12983.1 - 5.7 6.7 14.4 1.7 8.4 0.7 4.3 3 1 1 4 4 4 0 Laminin Domain II L31 PF09784.4 CEP12983.1 - 8.9 6.4 6.9 20 5.3 0.1 3.8 4 1 0 4 4 4 0 Mitochondrial ribosomal protein L31 Kelch_4 PF13418.1 CEP12984.1 - 7.9e-31 105.5 17.1 1.1e-10 41.0 0.1 6.4 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP12984.1 - 1.1e-26 91.8 13.1 6.8e-08 32.3 0.1 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CEP12984.1 - 2.4e-26 91.1 9.6 4.2e-08 32.9 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CEP12984.1 - 2.2e-23 81.5 11.2 4.8e-09 35.6 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 CEP12984.1 - 1.5e-20 72.7 11.3 2.8e-07 30.5 0.0 7.5 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP12984.1 - 1.5e-19 68.9 9.4 2.8e-06 26.8 0.1 6.4 6 0 0 6 6 6 5 Kelch motif CpXC PF14353.1 CEP12984.1 - 0.14 12.0 2.6 0.41 10.5 1.8 1.8 1 0 0 1 1 1 0 CpXC protein MSC PF09402.5 CEP12985.1 - 7.8e-36 123.4 0.0 1.4e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain PBP1_TM PF14812.1 CEP12985.1 - 0.00069 19.8 11.3 0.00069 19.8 7.8 2.9 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal HeH PF12949.2 CEP12985.1 - 0.0028 17.1 0.2 0.012 15.0 0.1 2.2 1 0 0 1 1 1 1 HeH/LEM domain NOA36 PF06524.7 CEP12985.1 - 5.4 6.1 7.7 9.6 5.3 5.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4203 PF13886.1 CEP12986.1 - 8.5e-24 84.1 36.9 1.1e-23 83.7 25.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Herpes_glycop PF01528.11 CEP12986.1 - 4.7 5.8 20.4 0.061 12.0 6.9 2.1 1 1 1 2 2 2 0 Herpesvirus glycoprotein M COX14 PF14880.1 CEP12986.1 - 9.4 5.9 6.2 1.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DEAD PF00270.24 CEP12987.1 - 5.7e-47 159.3 0.9 1.2e-46 158.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CEP12987.1 - 1.7e-23 81.9 0.4 3.5e-23 80.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CEP12987.1 - 4.3e-22 77.7 0.0 8.6e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP12987.1 - 0.014 15.2 0.1 0.074 12.8 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEP12987.1 - 0.19 11.8 0.9 1 9.4 0.5 2.4 2 1 0 2 2 2 0 AAA domain DDE_Tnp_4 PF13359.1 CEP12988.1 - 8.7e-12 44.9 0.0 1.4e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 CEP12988.1 - 0.08 12.4 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Peptidase_M16 PF00675.15 CEP12989.1 - 3.1e-57 192.5 0.4 4.8e-56 188.6 0.2 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CEP12989.1 - 3.6e-43 147.3 0.0 4.8e-42 143.7 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain PH PF00169.24 CEP12990.1 - 9.4e-11 41.8 0.0 1e-09 38.4 0.0 2.8 2 0 0 2 2 2 1 PH domain LRR_6 PF13516.1 CEP12990.1 - 1.7e-07 30.5 25.9 0.03 14.3 0.0 10.9 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.2 CEP12990.1 - 0.071 12.7 27.2 0.18 11.4 0.4 7.6 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) PH_11 PF15413.1 CEP12990.1 - 0.59 10.4 3.1 0.96 9.7 0.1 2.9 3 1 0 3 3 3 0 Pleckstrin homology domain LRR_7 PF13504.1 CEP12990.1 - 6.8 7.3 12.8 29 5.4 0.0 6.9 7 0 0 7 7 7 0 Leucine rich repeat AJAP1_PANP_C PF15298.1 CEP12991.1 - 0.0035 17.2 2.9 0.0035 17.2 2.0 3.3 2 2 1 3 3 3 1 AJAP1/PANP C-terminus MFS_2 PF13347.1 CEP12991.1 - 0.014 13.8 0.2 0.021 13.2 0.1 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein DUF3074 PF11274.3 CEP12992.1 - 4.9e-26 91.4 0.1 6.6e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Methyltransf_16 PF10294.4 CEP12993.1 - 2.4e-21 75.9 0.0 4.5e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase HLH PF00010.21 CEP12993.1 - 3.5e-18 65.0 2.7 9.7e-18 63.6 1.9 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PrmA PF06325.8 CEP12993.1 - 2e-06 27.1 0.0 3.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CEP12993.1 - 3.1e-06 27.7 0.0 9.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP12993.1 - 3.7e-06 26.6 0.0 8.1e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP12993.1 - 4.3e-05 23.9 0.4 0.00012 22.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CEP12993.1 - 5.7e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CEP12993.1 - 0.00013 21.9 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP12993.1 - 0.00066 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP12993.1 - 0.0011 19.3 0.0 0.0033 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP12993.1 - 0.0035 17.8 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ATG16 PF08614.6 CEP12993.1 - 0.02 14.7 5.6 0.051 13.3 3.9 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cons_hypoth95 PF03602.10 CEP12993.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 POP1 PF06978.6 CEP12993.1 - 0.12 12.0 6.7 0.025 14.2 2.3 1.6 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 DUF908 PF06012.7 CEP12993.1 - 0.42 9.8 5.4 0.39 9.9 2.6 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF908) LSM PF01423.17 CEP12995.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 LSM domain DUF868 PF05910.7 CEP12995.1 - 0.12 11.8 0.1 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) Nup35_RRM_2 PF14605.1 CEP12996.1 - 0.0011 18.7 0.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4278 PF14105.1 CEP12996.1 - 0.014 15.3 0.0 6.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4278) GreA_GreB_N PF03449.10 CEP12996.1 - 0.26 11.3 0.2 0.26 11.3 0.1 3.0 4 0 0 4 4 4 0 Transcription elongation factor, N-terminal Arg_tRNA_synt_N PF03485.11 CEP12996.1 - 0.64 10.6 7.2 7 7.2 0.2 3.1 3 0 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain IncA PF04156.9 CEP12996.1 - 5.4 6.5 18.3 21 4.6 0.0 3.0 2 1 0 2 2 2 0 IncA protein G-alpha PF00503.15 CEP12997.1 - 2.8e-131 437.8 6.5 3.3e-131 437.5 4.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP12997.1 - 3e-16 59.1 3.5 8e-12 44.7 0.2 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CEP12997.1 - 0.00024 21.5 0.0 0.55 10.7 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CEP12997.1 - 0.00048 20.0 0.1 0.19 11.6 0.0 2.3 1 1 0 2 2 2 2 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEP12997.1 - 0.0012 18.0 6.4 0.029 13.5 0.1 3.1 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CEP12997.1 - 0.014 14.8 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.15 CEP12997.1 - 0.016 14.7 0.0 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.13 CEP12997.1 - 0.068 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.18 CEP12997.1 - 0.096 11.4 0.2 0.24 10.1 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family MRP-L47 PF06984.8 CEP12998.1 - 4.4e-28 97.0 2.8 6.6e-28 96.4 2.0 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) priB_priC PF07445.7 CEP12998.1 - 0.0017 17.8 3.5 0.0019 17.6 2.4 1.3 1 1 0 1 1 1 1 Primosomal replication protein priB and priC Ribosomal_L29 PF00831.18 CEP12998.1 - 0.0025 17.4 2.0 0.071 12.8 1.4 2.3 1 1 0 1 1 1 1 Ribosomal L29 protein Glyco_hydro_63 PF03200.11 CEP12999.1 - 3e-245 815.8 0.4 2.2e-244 813.0 0.2 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 CEP12999.1 - 0.0017 17.1 0.0 0.0029 16.3 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Aldedh PF00171.17 CEP13000.1 - 3.7e-132 440.9 0.0 5.5e-132 440.3 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family XRN_N PF03159.13 CEP13000.1 - 6.8e-90 300.5 0.0 1.3e-89 299.6 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus LuxC PF05893.9 CEP13000.1 - 0.0018 17.0 0.0 0.0057 15.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) SAP18 PF06487.7 CEP13000.1 - 0.072 12.8 1.6 0.7 9.6 0.1 2.7 3 0 0 3 3 3 0 Sin3 associated polypeptide p18 (SAP18) Chs3p PF12271.3 CEP13002.1 - 1.1e-92 310.2 26.1 1.7e-85 286.5 15.3 2.0 1 1 1 2 2 2 2 Chitin synthase III catalytic subunit DSPc PF00782.15 CEP13003.1 - 2.5e-34 117.7 0.0 3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP13003.1 - 2.9e-05 23.5 0.0 3.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.20 CEP13004.1 - 2.7e-69 233.2 0.0 3.4e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13004.1 - 7e-29 100.6 0.0 8.7e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP13004.1 - 6.8e-08 31.8 0.2 8.6e-06 24.9 0.0 2.2 1 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CEP13004.1 - 0.00059 19.2 0.2 0.00059 19.2 0.1 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 CEP13004.1 - 0.0046 16.0 0.1 0.0072 15.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP13004.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family P16-Arc PF04699.9 CEP13005.1 - 7.1e-50 168.9 0.0 7.9e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 CEP13005.1 - 0.004 17.0 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family MgtE_N PF03448.12 CEP13005.1 - 0.071 13.4 0.1 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 MgtE intracellular N domain AMP-binding PF00501.23 CEP13006.1 - 2.6e-80 269.8 0.0 3.4e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme LigA PF07746.6 CEP13007.1 - 0.062 13.3 0.4 0.13 12.2 0.2 1.7 1 1 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit MFS_1 PF07690.11 CEP13009.1 - 1.6e-22 79.7 44.9 1.1e-18 67.1 18.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily HMG_CoA_synt_C PF08540.5 CEP13010.1 - 6.3e-101 337.5 3.6 9.2e-101 337.0 2.5 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 CEP13010.1 - 2.6e-88 294.1 0.3 4.1e-88 293.4 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.5 CEP13010.1 - 0.0063 16.5 0.1 2.5 8.1 0.1 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Guanylate_cyc_2 PF09778.4 CEP13011.1 - 2.2e-48 164.2 4.0 2.5e-26 92.2 0.6 2.0 1 1 1 2 2 2 2 Guanylylate cyclase Peptidase_C39_2 PF13529.1 CEP13011.1 - 1e-09 38.9 0.1 1e-08 35.6 0.1 2.0 1 1 0 1 1 1 1 Peptidase_C39 like family Transpep_BrtH PF14399.1 CEP13011.1 - 9.8e-06 25.0 0.1 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NlpC/p60-like transpeptidase Peptidase_C39 PF03412.10 CEP13011.1 - 0.00017 21.3 0.0 0.0035 17.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase C39 family Pkinase PF00069.20 CEP13012.1 - 7.5e-43 146.5 0.0 1.2e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13012.1 - 1.2e-27 96.5 0.0 1.7e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP13012.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 CEP13012.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIF1 PF05970.9 CEP13013.1 - 3.1e-43 148.1 0.0 4.7e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 CEP13013.1 - 3.8e-23 82.1 0.3 2.9e-21 76.0 0.0 2.5 1 1 1 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 CEP13013.1 - 4.7e-07 29.5 0.0 9.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP13013.1 - 0.00088 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CEP13013.1 - 0.0047 16.6 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 CEP13013.1 - 0.025 13.2 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 CEP13013.1 - 0.094 12.8 0.0 4.7 7.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain R-HINP1I PF11463.3 CEP13013.1 - 0.14 11.4 0.3 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease T2SE PF00437.15 CEP13013.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 CEP13013.1 - 0.18 10.7 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain DPBB_1 PF03330.13 CEP13015.1 - 8.3e-10 38.5 0.0 1.6e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Zn_clus PF00172.13 CEP13016.1 - 0.0086 15.9 16.1 0.014 15.2 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_9 PF00759.14 CEP13017.1 - 1.6e-56 192.0 4.4 2e-56 191.7 3.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.14 CEP13018.1 - 6e-36 124.2 0.1 6.7e-36 124.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 FGGY_C PF02782.11 CEP13019.1 - 2.2e-71 239.5 1.1 2.8e-70 235.9 0.5 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CEP13019.1 - 9.2e-50 169.2 0.1 1.4e-49 168.6 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DPBB_1 PF03330.13 CEP13020.1 - 2.7e-11 43.3 0.0 6.9e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP13020.1 - 5.7e-05 22.7 0.0 7.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Barwin family SAF_2 PF13144.1 CEP13020.1 - 0.0093 15.4 0.4 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 SAF-like zf-4CXXC_R1 PF10497.4 CEP13020.1 - 0.18 11.9 2.4 0.36 10.9 1.7 1.5 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 MIF PF01187.13 CEP13021.1 - 1.7e-13 50.6 0.0 1.8e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 CEP13021.1 - 0.00079 18.9 0.0 0.0085 15.6 0.0 2.0 2 0 0 2 2 2 1 Tautomerase enzyme PIP49_C PF12260.3 CEP13021.1 - 0.05 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF288 PF03385.12 CEP13021.1 - 0.097 11.1 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF288 FAR1 PF03101.10 CEP13023.1 - 2.5e-08 34.3 2.2 3.7e-08 33.7 1.5 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain BrkDBD PF09607.5 CEP13023.1 - 0.083 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain Glyco_hydro_18 PF00704.23 CEP13024.1 - 1e-88 298.1 0.6 1.2e-88 297.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 VTC PF09359.5 CEP13025.1 - 2.4e-77 259.7 0.0 3.9e-77 259.0 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEP13025.1 - 2.9e-19 69.9 2.3 1.4e-10 41.4 0.1 2.3 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 CEP13025.1 - 8.1e-11 41.9 3.1 1.6e-10 41.0 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Glycos_transf_4 PF00953.16 CEP13025.1 - 0.054 13.2 1.2 0.086 12.6 0.8 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 VTC PF09359.5 CEP13026.1 - 2.4e-83 279.4 0.0 7e-83 277.8 0.0 1.8 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEP13026.1 - 1.1e-10 41.8 21.0 0.00022 21.1 1.7 3.9 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.10 CEP13026.1 - 1.4e-10 41.2 4.0 1.4e-10 41.2 2.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Glycos_transf_4 PF00953.16 CEP13026.1 - 0.0039 17.0 2.4 0.0067 16.2 1.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 4 HEAT_EZ PF13513.1 CEP13027.1 - 1.5e-27 95.3 4.2 1.5e-10 41.2 0.0 10.2 9 3 4 13 13 12 5 HEAT-like repeat HEAT PF02985.17 CEP13027.1 - 3.5e-25 85.7 8.5 0.00043 20.1 0.0 9.0 9 0 0 9 9 8 6 HEAT repeat HEAT_2 PF13646.1 CEP13027.1 - 3.4e-22 78.5 0.9 6.5e-06 26.3 0.0 6.0 4 2 1 5 5 5 5 HEAT repeats Cnd1 PF12717.2 CEP13027.1 - 3.5e-11 43.2 2.5 0.00085 19.2 0.2 5.4 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 CEP13027.1 - 6e-11 42.1 0.0 4.1e-10 39.4 0.0 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 CEP13027.1 - 1.1e-10 41.7 0.0 0.002 18.5 0.0 6.0 4 2 3 7 7 7 4 Vacuolar 14 Fab1-binding region Arm PF00514.18 CEP13027.1 - 3.7e-09 36.0 5.9 0.17 11.7 0.1 7.6 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CEP13027.1 - 3.8e-07 29.7 0.3 0.17 11.2 0.0 4.9 4 2 1 5 5 5 2 CLASP N terminal Adaptin_N PF01602.15 CEP13027.1 - 3.1e-06 25.8 1.0 0.00047 18.6 0.0 3.4 3 1 1 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.3 CEP13027.1 - 9e-05 21.3 2.2 0.57 8.8 0.0 4.5 3 1 0 4 4 4 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 CEP13027.1 - 0.00043 19.9 3.4 0.36 10.4 0.0 4.6 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis ParcG PF10274.4 CEP13027.1 - 0.00052 19.9 4.2 0.83 9.5 0.0 4.4 6 0 0 6 6 5 2 Parkin co-regulated protein RasGEF_N_2 PF14663.1 CEP13027.1 - 0.0021 18.0 0.2 0.63 9.9 0.0 3.7 4 0 0 4 4 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Proteasom_PSMB PF10508.4 CEP13027.1 - 0.0022 16.3 0.0 0.71 8.0 0.0 3.0 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit UNC45-central PF11701.3 CEP13027.1 - 0.0077 15.8 0.7 0.0077 15.8 0.5 3.1 3 2 0 3 3 3 1 Myosin-binding striated muscle assembly central XPC-binding PF09280.6 CEP13027.1 - 0.0096 15.3 6.6 0.062 12.7 0.0 4.8 4 0 0 4 4 4 1 XPC-binding domain V-ATPase_H_N PF03224.9 CEP13027.1 - 0.021 13.9 3.3 0.27 10.3 0.1 3.0 4 0 0 4 4 4 0 V-ATPase subunit H Cohesin_HEAT PF12765.2 CEP13027.1 - 0.049 13.5 0.4 27 4.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Brix PF04427.13 CEP13028.1 - 7.3e-43 146.4 0.2 1e-42 145.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain RIO1 PF01163.17 CEP13028.1 - 0.13 11.5 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family RNA_pol_3_Rpc31 PF11705.3 CEP13028.1 - 1.5 8.6 11.7 2.4 8.0 8.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 EF_TS PF00889.14 CEP13029.1 - 7.1e-36 123.5 1.9 2.5e-33 115.2 0.1 2.6 2 1 0 2 2 2 1 Elongation factor TS UBA PF00627.26 CEP13029.1 - 0.00065 19.4 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Ribosomal_L7Ae PF01248.21 CEP13030.1 - 2.6e-27 94.1 0.0 2.9e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Thioredox_DsbH PF03190.10 CEP13031.1 - 2.8e-71 238.4 0.1 5e-71 237.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 CEP13031.1 - 1.3e-11 44.3 0.0 3.1e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.8 CEP13031.1 - 0.00017 20.7 0.4 0.00035 19.7 0.1 1.6 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 CEP13031.1 - 0.00039 18.8 0.0 0.00075 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Thioredoxin_2 PF13098.1 CEP13031.1 - 0.0034 17.5 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain BCDHK_Adom3 PF10436.4 CEP13032.1 - 0.0052 16.3 0.2 0.017 14.6 0.2 1.8 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF4600 PF15372.1 CEP13033.1 - 0.039 14.1 0.1 0.053 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) LOH1CR12 PF10158.4 CEP13034.1 - 0.089 12.5 0.4 1.5 8.5 0.0 2.0 1 1 1 2 2 2 0 Tumour suppressor protein BsuBI_PstI_RE PF06616.6 CEP13034.1 - 0.12 11.2 0.1 0.13 11.0 0.1 1.0 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus DDE_3 PF13358.1 CEP13035.1 - 6.1e-20 71.4 0.0 2e-18 66.5 0.0 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease MULE PF10551.4 CEP13035.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 MULE transposase domain rve PF00665.21 CEP13035.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain ATG16 PF08614.6 CEP13038.1 - 0.049 13.4 0.7 0.072 12.8 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CEP13038.1 - 0.055 11.9 0.5 0.057 11.8 0.4 1.1 1 0 0 1 1 1 0 AAA domain DUF1031 PF06275.6 CEP13038.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Baculo_PEP_C PF04513.7 CEP13038.1 - 0.11 12.3 0.2 0.13 12.1 0.1 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.10 CEP13038.1 - 0.2 11.8 0.9 0.52 10.5 0.6 1.8 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CCP_MauG PF03150.9 CEP13039.1 - 0.0073 16.6 0.0 0.0076 16.5 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase CYSTM PF12734.2 CEP13040.1 - 0.051 13.6 3.9 1.6 8.8 0.7 2.5 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Opi1 PF08618.5 CEP13040.1 - 0.12 11.2 2.0 0.15 10.9 1.4 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 LEM PF03020.10 CEP13041.1 - 4.5 6.8 6.8 1.2 8.6 0.4 2.4 2 0 0 2 2 2 0 LEM domain PIF1 PF05970.9 CEP13044.1 - 5.4e-36 124.2 0.2 9.4e-20 70.8 0.2 3.9 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 CEP13044.1 - 1.2e-24 87.1 0.0 2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RabGAP-TBC PF00566.13 CEP13047.1 - 1.6e-33 116.0 22.5 2.7e-33 115.2 10.8 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 CEP13047.1 - 8.2e-08 31.7 1.0 2.6e-05 23.6 0.0 3.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3548) DAO PF01266.19 CEP13048.1 - 1.8e-54 185.0 0.0 2.4e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP13048.1 - 2.5e-09 36.5 2.0 2.5e-08 33.2 1.4 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CEP13048.1 - 1.1e-07 31.3 1.1 5.7e-06 25.6 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CEP13048.1 - 9.5e-06 24.7 0.3 0.033 13.0 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 CEP13048.1 - 0.00092 19.1 0.6 0.0099 15.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP13048.1 - 0.0012 18.7 0.5 0.0051 16.8 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CEP13048.1 - 0.0018 17.2 0.1 0.087 11.7 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 CEP13048.1 - 0.0022 17.6 0.1 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CEP13048.1 - 0.017 15.4 0.6 0.083 13.2 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEP13048.1 - 0.041 12.9 0.2 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 CEP13048.1 - 0.089 11.2 0.3 0.16 10.3 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Ank_2 PF12796.2 CEP13049.1 - 2.3e-13 50.3 0.7 4.8e-13 49.2 0.5 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP13049.1 - 4.1e-11 43.0 0.5 1.6e-10 41.1 0.1 2.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP13049.1 - 5.9e-10 39.0 0.1 2.9e-09 36.8 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP13049.1 - 1e-09 37.6 1.9 5.3e-07 29.2 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 CEP13049.1 - 5.3e-09 35.4 0.2 1.5e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat RrnaAD PF00398.15 CEP13049.1 - 0.13 11.3 0.0 0.37 9.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase DUF1576 PF07613.6 CEP13049.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) Ribosomal_L18e PF00828.14 CEP13050.1 - 9.6e-32 110.0 1.4 1.4e-31 109.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 WD40 PF00400.27 CEP13051.1 - 1.2e-60 199.3 21.9 5.5e-12 45.0 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CEP13051.1 - 2.4e-45 154.0 1.2 8.4e-45 152.3 0.3 2.2 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit LisH PF08513.6 CEP13051.1 - 5.8e-05 22.7 1.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 1 LisH SNF2_N PF00176.18 CEP13053.1 - 2e-48 164.7 0.9 4.1e-48 163.7 0.7 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP13053.1 - 1.3e-10 40.9 0.0 3.3e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP13053.1 - 7.8e-07 29.0 0.1 6.4e-06 26.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 CEP13053.1 - 0.021 14.7 0.0 0.1 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain Ser_hydrolase PF06821.8 CEP13053.1 - 0.098 12.2 0.0 0.57 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Phage_coat PF09063.5 CEP13054.1 - 0.055 13.2 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 Phage PP7 coat protein CagE_TrbE_VirB PF03135.9 CEP13054.1 - 0.11 12.3 1.2 0.14 11.9 0.8 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF4653 PF15546.1 CEP13054.1 - 3.6 6.7 7.0 0.86 8.8 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) MULE PF10551.4 CEP13056.1 - 2.6e-05 24.2 0.4 5.3e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CEP13056.1 - 0.0006 18.4 1.9 0.00099 17.7 1.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DUF1247 PF06851.6 CEP13056.1 - 0.0041 16.7 1.6 0.57 9.8 0.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1247) LVIVD PF08309.6 CEP13058.1 - 0.1 11.5 0.1 0.24 10.4 0.1 1.6 1 0 0 1 1 1 0 LVIVD repeat Abhydrolase_3 PF07859.8 CEP13059.1 - 7e-23 81.3 6.8 6.9e-18 64.9 0.0 3.8 2 1 1 4 4 4 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CEP13059.1 - 7.5e-07 28.1 0.0 0.00033 19.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_2 PF02230.11 CEP13059.1 - 0.042 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CEP13059.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP13059.1 - 0.082 12.1 0.4 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndufs5 PF10200.4 CEP13059.1 - 0.14 12.1 0.2 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PTPA PF03095.10 CEP13059.1 - 0.17 11.0 0.2 0.27 10.3 0.2 1.2 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Mago-bind PF09282.5 CEP13060.1 - 1.3e-14 53.3 0.8 2.5e-14 52.5 0.6 1.5 1 0 0 1 1 1 1 Mago binding DUF3945 PF13101.1 CEP13060.1 - 0.15 11.4 2.0 0.25 10.6 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) DUF3373 PF11853.3 CEP13060.1 - 0.82 8.1 3.7 1 7.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) YwqJ-deaminase PF14431.1 CEP13061.1 - 0.03 14.1 0.3 0.052 13.3 0.2 1.6 1 0 0 1 1 1 0 YwqJ-like deaminase DASH_Dad2 PF08654.5 CEP13061.1 - 0.39 10.7 7.1 0.57 10.1 1.9 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad2 TSC22 PF01166.13 CEP13061.1 - 0.84 9.6 10.5 4.9 7.1 2.1 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family Viral_P18 PF04521.8 CEP13061.1 - 1.3 8.4 7.5 0.59 9.5 1.6 2.6 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Tropomyosin_1 PF12718.2 CEP13061.1 - 7.4 6.4 25.7 0.12 12.2 5.2 3.1 1 1 3 4 4 4 0 Tropomyosin like HSF_DNA-bind PF00447.12 CEP13062.1 - 1.9e-34 117.9 1.7 2.3e-34 117.6 0.1 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Tmemb_cc2 PF10267.4 CEP13062.1 - 0.0054 15.3 11.7 0.25 9.8 3.5 2.3 2 0 0 2 2 2 2 Predicted transmembrane and coiled-coil 2 protein SurA_N_2 PF13623.1 CEP13062.1 - 0.56 10.1 6.0 0.36 10.8 0.7 2.3 2 0 0 2 2 2 0 SurA N-terminal domain TBPIP PF07106.8 CEP13062.1 - 0.61 9.6 7.7 1.2 8.7 0.7 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3546 PF12066.3 CEP13065.1 - 0.066 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) RVT_1 PF00078.22 CEP13066.1 - 1.8e-20 73.1 0.7 6e-20 71.5 0.1 2.2 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP13066.1 - 1.3e-10 41.6 0.4 2.6e-10 40.6 0.3 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP13066.1 - 1.4e-05 24.7 1.0 3.2e-05 23.5 0.7 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Myb_DNA-bind_4 PF13837.1 CEP13067.1 - 0.051 13.7 0.1 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Involucrin_N PF10583.4 CEP13067.1 - 0.49 10.7 2.3 8.8 6.7 0.3 2.7 3 0 0 3 3 3 0 Involucrin of squamous epithelia N-terminus AOX PF01786.12 CEP13068.1 - 0.031 13.6 0.1 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Alternative oxidase DTW PF03942.10 CEP13068.1 - 0.035 13.3 0.2 0.074 12.2 0.1 1.5 1 0 0 1 1 1 0 DTW domain ERp29 PF07749.7 CEP13068.1 - 0.04 14.5 0.8 0.04 14.5 0.5 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Adaptin_binding PF10199.4 CEP13068.1 - 0.15 12.3 9.4 0.061 13.5 4.7 1.6 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4578 PF15147.1 CEP13068.1 - 0.79 10.0 5.0 0.68 10.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) DUF3682 PF12446.3 CEP13068.1 - 1.4 9.2 5.7 2.7 8.3 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) BEN PF10523.4 CEP13070.1 - 0.063 13.3 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 BEN domain DUF2673 PF10880.3 CEP13070.1 - 0.16 11.9 1.6 0.42 10.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2673) Effector_1 PF04518.7 CEP13072.1 - 0.019 13.9 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system TetR_C_4 PF08359.6 CEP13072.1 - 0.11 12.4 0.1 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region RVT_1 PF00078.22 CEP13073.1 - 8.3e-11 41.6 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CEP13073.1 - 0.042 13.6 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.22 CEP13074.1 - 2.8e-21 75.8 1.4 1.2e-20 73.8 0.1 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) YjgP_YjgQ PF03739.9 CEP13074.1 - 0.63 8.7 2.3 1.5 7.4 1.6 1.5 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RVT_1 PF00078.22 CEP13075.1 - 3.8e-16 59.1 0.0 1.1e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP13075.1 - 6.3e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Exo_endo_phos_2 PF14529.1 CEP13076.1 - 3.9e-09 36.1 0.2 9.6e-09 34.8 0.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP13076.1 - 2.7e-07 30.7 0.4 4.4e-07 30.0 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4185 PF13810.1 CEP13076.1 - 0.092 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Phage_int_SAM_4 PF13495.1 CEP13077.1 - 0.044 14.1 0.0 0.076 13.3 0.0 1.5 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HEAT_2 PF13646.1 CEP13078.1 - 0.00099 19.3 0.4 0.0013 18.9 0.3 1.2 1 0 0 1 1 1 1 HEAT repeats Aspzincin_M35 PF14521.1 CEP13078.1 - 0.12 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Plant_NMP1 PF06694.6 CEP13079.1 - 0.067 12.1 0.1 0.074 11.9 0.0 1.0 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Chromo PF00385.19 CEP13080.1 - 0.013 15.1 1.8 0.016 14.8 0.4 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Cid2 PF09774.4 CEP13081.1 - 1e-24 87.3 4.7 2e-24 86.4 3.3 1.4 1 1 0 1 1 1 1 Caffeine-induced death protein 2 DUF2362 PF10154.4 CEP13081.1 - 0.0036 16.0 1.1 0.004 15.8 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) NDUF_C2 PF06374.6 CEP13081.1 - 0.038 13.9 0.3 0.089 12.8 0.2 1.6 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) MRP-S28 PF10213.4 CEP13081.1 - 0.074 13.1 0.5 0.099 12.7 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein His_Phos_2 PF00328.17 CEP13081.1 - 0.14 11.5 0.8 0.16 11.2 0.5 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) ATP-synt_ab PF00006.20 CEP13082.1 - 2.6e-69 232.9 0.0 3.7e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEP13082.1 - 6.1e-26 91.1 0.0 1.5e-25 89.8 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEP13082.1 - 6.9e-21 74.2 0.6 1.9e-20 72.8 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CEP13082.1 - 2.9e-05 23.8 0.2 9.8e-05 22.1 0.1 1.9 2 1 0 2 2 2 1 HAS barrel domain PC-Esterase PF13839.1 CEP13083.1 - 4.2e-23 82.5 0.1 5.7e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.1 CEP13083.1 - 0.0094 15.9 2.8 0.14 12.2 1.9 2.5 1 1 0 1 1 1 1 PMR5 N terminal Domain Anp1 PF03452.9 CEP13084.1 - 8.6e-74 248.0 0.2 1.1e-73 247.6 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CEP13084.1 - 0.0085 15.7 0.2 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 SWIRM PF04433.12 CEP13085.1 - 5.9e-11 42.3 0.0 1.6e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 SWIRM domain ATG22 PF11700.3 CEP13086.1 - 2.6e-92 309.7 23.0 3.6e-92 309.3 16.0 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CEP13086.1 - 8e-13 47.8 39.7 8.9e-07 27.9 8.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF1075 PF06388.6 CEP13086.1 - 5.5 6.6 5.2 37 3.9 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1075) Vps5 PF09325.5 CEP13087.1 - 1.1e-16 60.8 11.0 1.2e-11 44.3 1.1 2.2 1 1 1 2 2 2 2 Vps5 C terminal like PX PF00787.19 CEP13087.1 - 4e-14 52.3 0.1 1.4e-11 44.2 0.0 2.7 2 0 0 2 2 2 2 PX domain Mnd1 PF03962.10 CEP13087.1 - 0.14 11.7 6.8 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Mnd1 family Cor1 PF04803.7 CEP13087.1 - 0.18 11.5 7.4 0.96 9.2 1.6 3.0 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region NPV_P10 PF05531.7 CEP13087.1 - 0.62 10.3 3.4 2.7 8.3 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 CEP13087.1 - 3.7 7.4 11.1 0.55 10.0 1.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RVT_1 PF00078.22 CEP13088.1 - 4.3e-14 52.3 0.0 6.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP13089.1 - 2.2e-13 50.3 0.0 3.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain FlxA PF14282.1 CEP13092.1 - 1.4 8.9 5.2 0.25 11.2 1.3 1.5 2 0 0 2 2 2 0 FlxA-like protein rve PF00665.21 CEP13093.1 - 6.5e-09 35.9 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 CEP13093.1 - 0.14 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease XPG_I PF00867.13 CEP13095.1 - 0.00035 20.5 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 XPG I-region ADPrib_exo_Tox PF03496.9 CEP13095.1 - 0.044 13.0 1.0 0.069 12.3 0.2 1.7 2 0 0 2 2 2 0 ADP-ribosyltransferase exoenzyme Mannitol_dh PF01232.18 CEP13095.1 - 0.05 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Pkinase PF00069.20 CEP13096.1 - 2.1e-54 184.4 0.2 1.1e-53 182.0 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13096.1 - 2.4e-22 79.2 0.0 4.3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CEP13096.1 - 0.0074 15.6 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CEP13096.1 - 0.039 13.6 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.19 CEP13097.1 - 1.9e-11 43.8 0.0 2.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CEP13097.1 - 3.2e-06 26.8 0.0 1.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 CEP13097.1 - 4.6e-06 26.6 0.1 1e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP13097.1 - 0.00011 22.0 0.1 0.0002 21.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEP13097.1 - 0.00056 19.8 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP13097.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEP13097.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4385 PF14328.1 CEP13097.1 - 0.02 14.8 0.2 0.03 14.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) Redoxin PF08534.5 CEP13101.1 - 8e-35 119.5 0.0 1.4e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CEP13101.1 - 1.3e-16 60.4 0.0 4.2e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family O-FucT PF10250.4 CEP13101.1 - 0.00015 21.0 0.8 0.007 15.5 0.0 3.1 3 1 0 3 3 3 1 GDP-fucose protein O-fucosyltransferase Exo_endo_phos PF03372.18 CEP13102.1 - 9e-21 74.9 0.3 1.7e-20 74.0 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 CEP13102.1 - 0.00019 21.1 0.6 0.5 10.3 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF726 PF05277.7 CEP13103.1 - 2.3e-81 273.3 0.0 3.7e-81 272.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) TauE PF01925.14 CEP13103.1 - 7.9e-05 22.2 1.3 7.9e-05 22.2 0.9 1.5 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE Abhydrolase_6 PF12697.2 CEP13103.1 - 0.015 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP13103.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 CEP13103.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) GNVR PF13807.1 CEP13103.1 - 0.099 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase zf-H2C2_2 PF13465.1 CEP13104.1 - 6.6e-19 67.2 27.2 1.3e-08 34.7 0.2 5.9 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP13104.1 - 2.8e-10 39.9 32.4 8e-06 25.9 3.4 6.2 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CEP13104.1 - 8.3e-09 35.0 15.0 0.0018 18.0 0.1 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP13104.1 - 4.3e-05 23.5 4.6 0.01 15.9 0.6 3.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CEP13104.1 - 0.092 13.1 44.5 0.25 11.7 2.1 6.9 7 0 0 7 7 7 0 C2H2-type zinc finger C1_4 PF07975.7 CEP13104.1 - 0.11 12.4 11.6 5.3 7.1 6.8 3.7 1 1 1 2 2 2 0 TFIIH C1-like domain GCR1_C PF12550.3 CEP13104.1 - 0.13 12.1 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes zf-C2H2_2 PF12756.2 CEP13104.1 - 8.4 6.5 17.6 21 5.2 6.9 4.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) UQ_con PF00179.21 CEP13105.1 - 1.2e-28 99.2 0.1 2.1e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CEP13105.1 - 0.013 15.3 0.9 0.017 15.0 0.1 1.6 2 0 0 2 2 2 0 RWD domain Ca_hom_mod PF14798.1 CEP13105.1 - 0.041 12.8 0.6 0.059 12.3 0.4 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator Band_3_cyto PF07565.8 CEP13105.1 - 0.067 12.6 0.7 0.083 12.3 0.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF912 PF06024.7 CEP13105.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex14_N PF04695.8 CEP13105.1 - 2.6 8.0 9.9 1.3 9.0 5.1 1.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_6 PF12697.2 CEP13106.1 - 7.4e-23 81.6 0.1 8.9e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CEP13106.1 - 6.4e-20 70.7 0.1 1.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 CEP13106.1 - 9.8e-16 57.8 0.2 3e-15 56.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP13106.1 - 4e-09 36.3 1.4 2e-06 27.5 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CEP13106.1 - 0.0027 17.1 0.4 0.067 12.6 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CEP13106.1 - 0.0061 15.8 0.2 0.037 13.2 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1749 PF08538.5 CEP13106.1 - 0.015 14.1 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF3089 PF11288.3 CEP13106.1 - 0.021 13.9 0.0 0.058 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Thioesterase PF00975.15 CEP13106.1 - 0.057 13.6 0.2 1.8 8.7 0.0 2.5 2 1 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.20 CEP13106.1 - 0.062 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 CEP13106.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 CEP13106.1 - 0.084 12.1 0.1 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Oxysterol_BP PF01237.13 CEP13107.1 - 1.5e-105 352.5 0.0 2.2e-105 352.0 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CEP13107.1 - 4.4e-12 45.8 0.3 1.9e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain GOLD_2 PF13897.1 CEP13107.1 - 0.00013 22.1 0.2 0.047 13.9 0.0 2.5 2 0 0 2 2 2 2 Golgi-dynamics membrane-trafficking PH PF00169.24 CEP13107.1 - 0.061 13.5 0.8 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 PH domain Cwf_Cwc_15 PF04889.7 CEP13108.1 - 0.09 12.4 0.2 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4379 PF14311.1 CEP13109.1 - 0.1 12.4 0.1 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Iso_dh PF00180.15 CEP13110.1 - 0.02 13.8 0.5 0.031 13.2 0.3 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase dsDNA_bind PF01984.15 CEP13112.1 - 0.014 15.3 9.2 0.014 15.3 6.4 2.2 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DUF87 PF01935.12 CEP13112.1 - 0.084 12.6 2.5 0.12 12.1 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_24 PF13479.1 CEP13112.1 - 1.1 8.7 5.9 3.5 7.1 3.0 1.8 1 1 1 2 2 2 0 AAA domain SSPI PF14098.1 CEP13112.1 - 7.9 6.4 9.1 17 5.4 0.4 3.3 2 1 1 3 3 3 0 Small, acid-soluble spore protein I Helitron_like_N PF14214.1 CEP13113.1 - 4.4e-09 36.3 0.8 1e-08 35.1 0.1 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Sigma70_ECF PF07638.6 CEP13114.1 - 0.19 11.3 2.6 0.26 10.9 1.8 1.3 1 1 0 1 1 1 0 ECF sigma factor Exo_endo_phos_2 PF14529.1 CEP13115.1 - 6e-06 25.8 0.4 3.9e-05 23.2 0.3 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP13115.1 - 1.5e-05 25.1 0.2 1.9e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CASP_C PF08172.7 CEP13116.1 - 0.00065 18.7 1.3 0.00075 18.5 0.9 1.2 1 0 0 1 1 1 1 CASP C terminal RE_NgoFVII PF09565.5 CEP13116.1 - 0.0083 15.1 0.3 0.0098 14.8 0.2 1.1 1 0 0 1 1 1 1 NgoFVII restriction endonuclease Anp1 PF03452.9 CEP13118.1 - 7.7e-83 277.7 0.2 1.1e-82 277.2 0.1 1.2 1 0 0 1 1 1 1 Anp1 GATase_4 PF13230.1 CEP13118.1 - 8.7e-17 60.6 0.1 4.3e-16 58.3 0.0 2.0 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 CEP13118.1 - 4.3e-09 36.4 0.0 8.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CEP13118.1 - 3.4e-08 32.5 0.0 1.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferases class-II SMC_hinge PF06470.8 CEP13118.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Rho_N PF07498.7 CEP13118.1 - 0.16 11.7 0.2 0.38 10.5 0.2 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain NAD_Gly3P_dh_N PF01210.18 CEP13120.1 - 3.5e-54 182.8 0.3 6.6e-54 181.8 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CEP13120.1 - 5.2e-52 175.5 0.2 8.4e-52 174.8 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CEP13120.1 - 0.0005 20.4 0.5 0.9 10.0 0.1 2.4 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.17 CEP13121.1 - 2.3e-15 55.9 0.0 4.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP13121.1 - 1.5e-13 50.4 0.0 2.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP13121.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSF_DNA-bind PF00447.12 CEP13122.1 - 4.4e-37 126.3 2.2 4.4e-37 126.3 1.5 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding ALIX_LYPXL_bnd PF13949.1 CEP13122.1 - 0.0039 16.2 5.5 0.0058 15.6 3.8 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Prenyltransf PF01255.14 CEP13122.1 - 0.006 15.7 0.5 0.01 14.9 0.3 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Cep57_CLD_2 PF14197.1 CEP13122.1 - 0.02 14.7 2.7 0.042 13.7 1.9 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Syntaxin_2 PF14523.1 CEP13122.1 - 0.031 14.3 3.7 0.077 13.0 2.6 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Blo-t-5 PF11642.3 CEP13122.1 - 0.059 13.1 1.3 0.1 12.3 0.9 1.3 1 0 0 1 1 1 0 Mite allergen Blo t 5 DUF3461 PF11944.3 CEP13122.1 - 0.12 12.1 2.9 0.098 12.5 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) IncA PF04156.9 CEP13122.1 - 0.29 10.7 2.9 0.49 9.9 2.0 1.3 1 0 0 1 1 1 0 IncA protein DUF4298 PF14131.1 CEP13122.1 - 0.87 9.5 8.6 0.21 11.4 3.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) HD_assoc PF13286.1 CEP13122.1 - 2 8.7 5.0 6.8 7.0 3.5 1.9 1 0 0 1 1 1 0 Phosphohydrolase-associated domain PEX11 PF05648.9 CEP13123.1 - 3.4e-20 72.2 0.4 4.6e-20 71.8 0.3 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MARVEL PF01284.18 CEP13125.1 - 4.2e-12 46.1 12.4 6.8e-12 45.4 8.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF1049 PF06305.6 CEP13125.1 - 0.15 11.5 0.1 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Fasciclin PF02469.17 CEP13126.1 - 2.5e-28 98.6 15.5 4.8e-23 81.5 1.6 4.0 3 1 0 3 3 3 3 Fasciclin domain Oxidored_FMN PF00724.15 CEP13127.1 - 1.1e-72 244.8 0.0 1.4e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4449 PF14613.1 CEP13128.1 - 5.7e-08 32.8 2.4 5.7e-08 32.8 1.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) ACBP PF00887.14 CEP13129.1 - 2.2e-28 97.7 0.3 5.3e-28 96.5 0.2 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein TCO89 PF10452.4 CEP13129.1 - 9.9e-09 34.6 7.1 9.9e-09 34.6 4.9 2.5 1 1 2 3 3 3 1 TORC1 subunit TCO89 DUF2680 PF10925.3 CEP13129.1 - 0.013 15.3 1.3 3.8 7.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) CCDC92 PF14916.1 CEP13129.1 - 0.025 14.1 1.0 0.11 12.1 0.2 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF919 PF06034.6 CEP13129.1 - 0.23 11.1 3.3 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Fib_alpha PF08702.5 CEP13129.1 - 6.5 6.8 13.2 1.6 8.8 1.9 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 CEP13130.1 - 6.5e-56 184.3 18.2 2.6e-10 39.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CEP13130.1 - 0.0034 17.1 0.0 2 8.1 0.0 2.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CEP13130.1 - 0.098 10.7 0.6 4.5 5.2 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 RRM_1 PF00076.17 CEP13131.1 - 1.1e-18 66.5 0.8 2.5e-18 65.4 0.6 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP13131.1 - 1.2e-10 41.2 0.1 2.5e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CEP13131.1 - 4.9e-10 38.9 1.0 4.8e-08 32.5 0.1 2.5 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 CEP13131.1 - 1.1e-06 28.3 0.5 2.7e-06 27.1 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RicinB_lectin_2 PF14200.1 CEP13132.1 - 2.7e-15 56.6 0.3 2.9e-10 40.4 0.0 2.7 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CEP13132.1 - 2.3e-14 53.4 0.0 1e-08 35.2 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain UEV PF05743.8 CEP13132.1 - 0.055 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 UEV domain MgtE PF01769.11 CEP13133.1 - 4.6e-12 46.3 3.1 1.2e-11 45.0 2.1 1.7 1 0 0 1 1 1 1 Divalent cation transporter Tox-MPTase3 PF15639.1 CEP13133.1 - 0.042 13.6 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 3 Aminotran_3 PF00202.16 CEP13133.1 - 0.063 12.1 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Aminotransferase class-III MgtE PF01769.11 CEP13134.1 - 1.1e-12 48.3 0.1 2.1e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Divalent cation transporter PAP2_3 PF14378.1 CEP13134.1 - 0.03 13.8 0.3 0.039 13.4 0.2 1.2 1 0 0 1 1 1 0 PAP2 superfamily UcrQ PF02939.11 CEP13134.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 UcrQ family DUF1440 PF07274.7 CEP13134.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) BCDHK_Adom3 PF10436.4 CEP13135.1 - 3.9e-43 146.7 0.0 8.7e-43 145.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CEP13135.1 - 2e-17 62.8 0.1 2.5e-16 59.3 0.1 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CEP13135.1 - 2.3e-08 33.7 0.0 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CEP13135.1 - 0.0015 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Pox_Rif PF03340.8 CEP13135.1 - 0.044 11.8 0.0 0.062 11.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus rifampicin resistance protein PCRF PF03462.13 CEP13135.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 PCRF domain IBR PF01485.16 CEP13137.1 - 2.6e-22 78.4 41.1 2.8e-11 43.1 3.3 4.6 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 CEP13137.1 - 8.8e-09 35.0 33.5 4.3e-06 26.4 3.2 3.5 3 0 0 3 3 3 3 Ring finger domain zf-C3HC4_2 PF13923.1 CEP13137.1 - 2.4e-06 27.4 4.5 2.4e-06 27.4 3.1 4.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP13137.1 - 7.9e-05 22.2 3.5 7.9e-05 22.2 2.4 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP13137.1 - 0.0049 16.5 5.5 0.0049 16.5 3.8 3.4 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEP13137.1 - 0.0063 16.3 1.0 0.0063 16.3 0.7 5.1 4 1 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP13137.1 - 0.016 14.8 0.8 0.016 14.8 0.5 3.8 3 0 0 3 3 3 0 RING-type zinc-finger Acetyltransf_10 PF13673.1 CEP13139.1 - 7.8e-05 22.7 0.0 0.12 12.5 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CEP13139.1 - 0.00017 21.6 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP13139.1 - 0.00027 20.9 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family TPR_1 PF00515.23 CEP13140.1 - 0.0019 17.6 0.0 0.0046 16.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-MYND PF01753.13 CEP13140.1 - 0.0035 17.1 15.9 0.0043 16.9 9.2 2.3 2 0 0 2 2 2 1 MYND finger TPR_2 PF07719.12 CEP13140.1 - 0.027 14.3 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2786 PF10979.3 CEP13140.1 - 0.37 10.5 1.8 26 4.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Aminotran_5 PF00266.14 CEP13141.1 - 2.2e-30 105.6 0.0 2.8e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CEP13141.1 - 0.0002 19.7 0.1 0.00029 19.2 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 CEP13141.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 B12 binding domain AAA PF00004.24 CEP13142.1 - 3.7e-64 214.8 0.0 8.5e-44 148.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEP13142.1 - 1.2e-08 35.8 0.3 0.0062 17.3 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CEP13142.1 - 1.4e-07 31.6 0.4 0.0066 16.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CEP13142.1 - 1.6e-07 31.5 12.4 0.001 19.0 0.0 4.6 5 1 1 6 6 4 2 AAA ATPase domain AAA_33 PF13671.1 CEP13142.1 - 2.9e-07 30.4 0.0 0.0083 16.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CEP13142.1 - 1.7e-06 28.3 0.0 0.069 13.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CEP13142.1 - 2.2e-06 26.9 0.0 0.0026 16.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CEP13142.1 - 3.5e-06 27.0 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CEP13142.1 - 3.8e-06 27.0 0.0 0.051 13.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 CEP13142.1 - 4.1e-06 26.3 0.3 0.0021 17.4 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CEP13142.1 - 7.5e-06 25.8 0.0 0.081 12.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CEP13142.1 - 2e-05 24.3 0.0 0.011 15.4 0.0 3.6 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 CEP13142.1 - 3.2e-05 23.5 1.1 0.3 10.7 0.0 3.2 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 CEP13142.1 - 4.2e-05 23.2 0.0 0.0024 17.5 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CEP13142.1 - 6.6e-05 22.6 0.1 0.73 9.4 0.0 3.2 3 0 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.12 CEP13142.1 - 7e-05 22.3 0.2 0.001 18.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 CEP13142.1 - 0.0002 20.2 0.0 0.013 14.2 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus Arch_ATPase PF01637.13 CEP13142.1 - 0.00021 21.0 0.0 0.23 11.1 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 CEP13142.1 - 0.00051 18.9 0.0 0.62 8.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_2 PF07724.9 CEP13142.1 - 0.00052 19.9 0.0 0.021 14.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CEP13142.1 - 0.00066 18.9 0.1 0.028 13.5 0.1 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CEP13142.1 - 0.0013 18.4 0.3 0.091 12.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 CEP13142.1 - 0.0017 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 CEP13142.1 - 0.0025 17.5 0.0 3.4 7.3 0.0 3.0 3 0 0 3 3 2 1 NTPase DUF815 PF05673.8 CEP13142.1 - 0.0028 16.6 0.0 2.5 6.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) KaiC PF06745.8 CEP13142.1 - 0.012 14.7 1.5 0.015 14.4 0.0 1.8 2 0 0 2 2 1 0 KaiC AAA_10 PF12846.2 CEP13142.1 - 0.014 14.8 0.1 3.7 6.8 0.0 2.9 2 1 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 CEP13142.1 - 0.014 15.6 0.7 2.5 8.3 0.0 3.3 3 0 0 3 3 3 0 ABC transporter Sigma54_activat PF00158.21 CEP13142.1 - 0.033 13.6 0.0 0.81 9.1 0.0 3.0 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_11 PF13086.1 CEP13142.1 - 0.034 13.7 0.7 1.9 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.6 CEP13142.1 - 0.05 13.1 0.0 0.38 10.3 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CEP13142.1 - 0.059 12.5 0.1 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 CEP13142.1 - 0.078 12.5 1.7 7.3 6.1 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain Vps4_C PF09336.5 CEP13142.1 - 0.095 12.6 0.1 13 5.8 0.0 3.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_23 PF13476.1 CEP13142.1 - 3.7 7.8 9.1 6.1 7.1 0.0 3.6 4 0 0 4 4 4 0 AAA domain TPR_11 PF13414.1 CEP13143.1 - 4.6e-18 64.6 3.5 1.2e-06 28.0 0.0 5.5 3 1 2 5 5 5 3 TPR repeat TPR_2 PF07719.12 CEP13143.1 - 1.2e-17 62.2 0.3 0.00067 19.3 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CEP13143.1 - 4.1e-13 48.3 1.3 0.00015 21.2 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP13143.1 - 1.2e-10 41.5 3.3 0.15 12.4 0.0 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP13143.1 - 1.9e-10 41.1 0.2 0.016 15.8 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP13143.1 - 2.1e-10 40.2 0.1 0.47 11.2 0.0 6.3 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEP13143.1 - 1.8e-09 37.3 2.3 0.0033 17.3 0.0 6.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP13143.1 - 3.5e-07 29.5 9.2 0.00011 21.7 0.1 5.8 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 CEP13143.1 - 1.8e-06 27.2 2.8 0.0032 16.5 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP13143.1 - 2.1e-06 27.4 1.0 0.12 12.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CEP13143.1 - 4.8e-06 26.6 0.4 0.0093 16.0 0.2 3.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CEP13143.1 - 6.1e-05 22.5 0.6 0.37 10.7 0.0 4.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP13143.1 - 7.8e-05 22.8 7.3 0.62 10.6 0.0 5.8 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEP13143.1 - 0.0052 16.5 0.1 1.7 8.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat CDC37_M PF08565.6 CEP13143.1 - 0.029 13.8 0.2 0.073 12.5 0.0 1.8 2 0 0 2 2 1 0 Cdc37 Hsp90 binding domain TPR_10 PF13374.1 CEP13143.1 - 0.25 11.3 7.0 8.5 6.4 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Hexokinase_2 PF03727.11 CEP13144.1 - 5.5e-80 268.0 0.9 6.2e-80 267.9 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 CEP13144.1 - 1.1e-71 240.4 0.4 2.5e-71 239.2 0.3 1.6 1 0 0 1 1 1 1 Hexokinase Bac_DNA_binding PF00216.16 CEP13144.1 - 0.019 14.9 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial DNA-binding protein PqqD PF05402.7 CEP13144.1 - 0.05 13.6 0.2 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Peptidase_S8 PF00082.17 CEP13145.1 - 1.9e-48 165.0 16.5 2e-47 161.7 11.4 2.1 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 CEP13145.1 - 2.5e-18 65.6 1.6 6.9e-18 64.2 1.1 1.8 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 CEP13145.1 - 7.7e-12 45.6 1.0 7.7e-12 45.6 0.7 2.8 3 0 0 3 3 3 1 Fn3-like domain (DUF1034) LNS2 PF08235.8 CEP13148.1 - 6e-69 230.6 0.0 9.4e-69 229.9 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CEP13148.1 - 4.6e-37 126.0 0.0 8.9e-37 125.1 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 CEP13148.1 - 0.0017 18.2 1.2 0.0017 18.2 0.8 4.1 4 1 0 4 4 4 1 Drug resistance and apoptosis regulator HSP70 PF00012.15 CEP13149.1 - 3.5e-258 857.5 10.9 4.3e-258 857.1 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP13149.1 - 5.4e-17 61.3 0.1 9.5e-17 60.5 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CEP13149.1 - 0.011 14.8 0.8 0.025 13.7 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CEP13149.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Speriolin_N PF15058.1 CEP13149.1 - 0.049 13.5 0.2 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Speriolin N terminus Actin PF00022.14 CEP13150.1 - 3e-51 174.0 0.0 4.2e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Actin Asp_protease_2 PF13650.1 CEP13151.1 - 0.00059 20.2 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP13151.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Myb_DNA-bind_6 PF13921.1 CEP13153.1 - 7.6e-06 25.9 0.1 2.9e-05 24.0 0.0 2.1 3 1 0 3 3 3 1 Myb-like DNA-binding domain bZIP_C PF12498.3 CEP13153.1 - 8.7 7.6 9.1 75 4.5 6.5 2.3 2 1 0 2 2 2 0 Basic leucine-zipper C terminal DSHCT PF08148.7 CEP13154.1 - 7.8e-49 165.3 0.5 4e-47 159.7 0.4 2.5 1 1 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 CEP13154.1 - 5.2e-12 45.5 0.1 1e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 CEP13154.1 - 8.1e-07 28.8 0.0 2.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP13155.1 - 2.1e-20 72.9 0.1 3.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CEP13155.1 - 0.0022 17.8 0.1 0.047 13.5 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DNA_pol_A_exo1 PF01612.15 CEP13156.1 - 1.4e-10 40.9 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Cation_efflux PF01545.16 CEP13157.1 - 3.5e-24 85.3 1.1 6.5e-24 84.4 0.8 1.3 1 0 0 1 1 1 1 Cation efflux family Macoilin PF09726.4 CEP13157.1 - 1.3 7.2 17.2 2.6 6.2 11.9 1.4 1 0 0 1 1 1 0 Transmembrane protein zf-AN1 PF01428.11 CEP13158.1 - 9.1e-18 63.8 24.2 5.6e-10 38.9 5.3 3.1 2 1 1 3 3 3 2 AN1-like Zinc finger zf-C3HC PF07967.8 CEP13158.1 - 0.59 9.8 9.4 3.5 7.3 2.5 2.4 1 1 1 2 2 2 0 C3HC zinc finger-like zinc_ribbon_4 PF13717.1 CEP13158.1 - 0.64 9.7 5.1 0.76 9.5 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CEP13158.1 - 0.88 9.2 5.2 0.82 9.2 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 CEP13158.1 - 3.8 7.4 22.4 36 4.3 0.9 3.5 1 1 1 2 2 2 0 IBR domain DNA_RNApol_7kD PF03604.8 CEP13158.1 - 5.3 6.6 7.8 2.3 7.7 0.2 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L28 PF00830.14 CEP13159.1 - 1.8e-22 78.9 1.1 1.8e-22 78.9 0.7 1.5 2 0 0 2 2 2 1 Ribosomal L28 family Chromo_shadow PF01393.14 CEP13160.1 - 1e-09 38.0 0.3 1.8e-08 34.0 0.1 2.3 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 CEP13160.1 - 2.1e-08 33.6 1.0 2.1e-08 33.6 0.7 2.4 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP13160.1 - 0.047 13.4 0.1 0.047 13.4 0.1 2.1 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain DUF898 PF05987.8 CEP13168.1 - 0.0045 15.9 0.4 0.0053 15.6 0.3 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) SNF2_N PF00176.18 CEP13169.1 - 2.2e-66 223.7 0.1 2.2e-66 223.7 0.1 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 CEP13169.1 - 1.4e-14 53.4 2.7 7.6e-09 35.1 0.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CEP13169.1 - 7.4e-14 51.3 0.0 3.9e-13 49.0 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ipi1_N PF12333.3 CEP13170.1 - 0.086 12.8 0.4 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation RVT_1 PF00078.22 CEP13171.1 - 3.4e-17 62.5 0.2 5.2e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1241 PF06840.6 CEP13171.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DDE_3 PF13358.1 CEP13172.1 - 1.3e-26 93.1 0.0 3.2e-26 91.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 CEP13172.1 - 0.041 13.9 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_1 PF00126.22 CEP13172.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.1 CEP13172.1 - 0.16 11.5 0.1 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Polyketide_cyc PF03364.15 CEP13174.1 - 5.2e-08 32.9 0.3 2.8e-07 30.5 0.2 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 CEP13174.1 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Trehalose_PPase PF02358.11 CEP13174.1 - 0.021 13.7 1.3 0.068 12.0 0.1 2.0 2 0 0 2 2 2 0 Trehalose-phosphatase DNA_pol_A_exo1 PF01612.15 CEP13176.1 - 3.2e-08 33.2 0.0 1.6e-06 27.7 0.0 2.1 1 1 1 2 2 2 2 3'-5' exonuclease CotH PF08757.6 CEP13177.1 - 2.8e-41 141.8 0.2 4.2e-41 141.2 0.2 1.2 1 0 0 1 1 1 1 CotH protein Fra10Ac1 PF09725.4 CEP13178.1 - 1.6e-47 160.4 6.1 4.1e-47 159.1 4.2 1.7 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 WD40 PF00400.27 CEP13178.1 - 6.9e-21 73.2 9.2 1.1e-08 34.6 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CEP13178.1 - 7.5e-15 54.6 0.0 2.3e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.20 CEP13179.1 - 5.6e-55 186.2 0.0 6.4e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13179.1 - 7.8e-20 71.0 0.0 7.5e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP13179.1 - 4.9e-05 22.4 0.0 7.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CEP13179.1 - 0.043 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 CEP13179.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CEP13179.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GDA1_CD39 PF01150.12 CEP13180.1 - 1.2e-97 327.2 0.0 1.6e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CEP13180.1 - 0.0021 17.3 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Fungal_trans PF04082.13 CEP13181.1 - 2.8e-08 32.9 0.6 1.8e-07 30.2 0.3 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Vps53_N PF04100.7 CEP13182.1 - 0.0013 17.5 0.7 0.0017 17.2 0.1 1.4 1 1 0 1 1 1 1 Vps53-like, N-terminal Erythro_esteras PF05139.9 CEP13182.1 - 0.022 13.9 0.6 0.027 13.6 0.4 1.0 1 0 0 1 1 1 0 Erythromycin esterase TMV_coat PF00721.16 CEP13182.1 - 0.15 11.9 2.4 0.16 11.9 0.8 1.5 1 1 0 2 2 2 0 Virus coat protein (TMV like) PXA PF02194.10 CEP13182.1 - 0.23 10.9 1.9 0.25 10.9 1.3 1.2 1 0 0 1 1 1 0 PXA domain DUF4200 PF13863.1 CEP13182.1 - 0.28 11.1 8.0 0.37 10.7 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 CEP13183.1 - 0.013 15.2 0.2 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein YopE_N PF09020.5 CEP13183.1 - 0.033 14.2 0.6 0.91 9.5 0.0 2.4 1 1 1 2 2 2 0 YopE, N terminal PEGSRP PF07623.6 CEP13184.1 - 0.55 9.5 0.2 0.55 9.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) RhoGAP PF00620.22 CEP13185.1 - 2e-15 56.7 1.1 6e-15 55.1 0.8 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 CEP13185.1 - 3.9e-09 36.5 0.2 2.1e-08 34.2 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain PRC PF05239.11 CEP13185.1 - 0.014 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 PRC-barrel domain MFS_1 PF07690.11 CEP13186.1 - 2.3e-54 184.4 22.7 5.1e-54 183.3 14.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP13186.1 - 4.6e-17 61.7 4.3 4.6e-17 61.7 3.0 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 CEP13186.1 - 3.9e-10 38.5 1.8 3.9e-10 38.5 1.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CEP13186.1 - 4.4e-06 25.0 6.2 0.0019 16.3 4.3 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF791 PF05631.9 CEP13186.1 - 0.00043 19.0 0.5 0.0011 17.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 CEP13186.1 - 0.66 8.0 8.1 0.083 10.9 2.6 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector HLH PF00010.21 CEP13187.1 - 3.9e-13 48.8 1.1 3.9e-13 48.8 0.8 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Myc-LZ PF02344.10 CEP13187.1 - 0.092 12.3 2.7 2.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain zf-C2H2 PF00096.21 CEP13188.1 - 1.6e-10 40.6 11.7 4.3e-06 26.7 0.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP13188.1 - 4.3e-09 36.0 10.2 0.0001 22.3 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP13188.1 - 5.3e-07 29.6 4.0 5.3e-07 29.6 2.8 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEP13188.1 - 0.017 14.9 0.7 0.16 11.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3973 PF13119.1 CEP13188.1 - 0.019 14.8 0.1 0.073 13.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) zf-C2H2_jaz PF12171.3 CEP13188.1 - 0.14 12.3 3.8 5.6 7.2 0.9 3.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 CEP13188.1 - 0.15 11.7 1.9 2.1 8.1 0.1 2.5 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger LMBR1 PF04791.11 CEP13189.1 - 2.5e-09 36.2 9.3 6.5e-07 28.3 1.0 2.1 2 0 0 2 2 2 2 LMBR1-like membrane protein UPF0164 PF03687.8 CEP13189.1 - 0.063 11.7 0.3 0.1 11.0 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) Dopey_N PF04118.9 CEP13190.1 - 3.2e-108 361.1 0.1 3.2e-108 361.1 0.0 2.3 2 1 1 3 3 3 1 Dopey, N-terminal NOB1_Zn_bind PF08772.6 CEP13191.1 - 2.5e-28 97.7 2.4 5e-28 96.7 1.7 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 CEP13191.1 - 0.012 15.4 0.8 0.027 14.2 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon PIN PF01850.16 CEP13191.1 - 0.033 14.5 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 PIN domain zf-ribbon_3 PF13248.1 CEP13191.1 - 0.17 11.1 2.8 0.57 9.4 2.0 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Rpr2 PF04032.11 CEP13191.1 - 0.27 11.1 3.1 0.67 9.8 1.9 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Rad1 PF02144.11 CEP13192.1 - 6.4e-09 34.9 0.2 8e-09 34.6 0.1 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AlaDh_PNT_N PF05222.10 CEP13193.1 - 7.7e-31 106.9 0.0 1.1e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CEP13193.1 - 1.5e-12 47.4 0.0 2.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain EIIBC-GUT_N PF03612.9 CEP13193.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Glyco_hydro_20 PF00728.17 CEP13194.1 - 3.8e-101 338.7 0.9 5.1e-101 338.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CEP13194.1 - 2.1e-13 51.0 0.5 3.2e-12 47.2 0.2 2.4 1 1 1 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CEP13194.1 - 7.7e-05 23.2 0.2 0.0027 18.2 0.1 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF3186 PF11382.3 CEP13195.1 - 0.1 11.7 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Cgr1 PF03879.9 CEP13195.1 - 0.12 12.5 5.0 0.15 12.2 3.4 1.2 1 0 0 1 1 1 0 Cgr1 family IncA PF04156.9 CEP13195.1 - 9.3 5.7 7.9 11 5.5 5.5 1.3 1 1 0 1 1 1 0 IncA protein RGS PF00615.14 CEP13196.1 - 2.1e-28 98.7 0.2 9.3e-28 96.6 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 CEP13196.1 - 3.8e-12 45.7 0.4 2.6e-06 27.0 0.1 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_4 PF12763.2 CEP13197.1 - 3.2e-42 142.4 0.0 8.2e-16 57.6 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CEP13197.1 - 1.4e-06 28.2 0.0 0.11 12.6 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CEP13197.1 - 6.5e-05 21.9 0.0 1.3 8.5 0.0 4.6 4 0 0 4 4 4 1 EF hand UBA PF00627.26 CEP13197.1 - 0.0002 21.0 0.0 0.00058 19.6 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Reo_sigmaC PF04582.7 CEP13197.1 - 0.18 10.9 5.4 0.31 10.1 2.4 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Clathrin_lg_ch PF01086.12 CEP13199.1 - 3.7e-40 138.2 9.0 5.5e-40 137.6 6.2 1.3 1 0 0 1 1 1 1 Clathrin light chain Methyltransf_16 PF10294.4 CEP13199.1 - 6e-25 87.6 0.0 9.8e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase 6PF2K PF01591.13 CEP13200.1 - 7.9e-48 162.4 0.0 1.3e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEP13200.1 - 5.8e-24 84.9 0.3 8.1e-24 84.4 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3606 PF12244.3 CEP13204.1 - 0.052 13.1 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) ABC_tran PF00005.22 CEP13205.1 - 9e-49 165.2 0.0 6.7e-28 97.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CEP13205.1 - 6.3e-45 153.7 25.7 1.5e-25 90.1 3.2 3.5 3 1 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 CEP13205.1 - 1.1e-11 44.4 0.7 9.4e-05 21.7 0.2 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEP13205.1 - 3.1e-07 30.9 0.0 0.00085 19.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 CEP13205.1 - 2.3e-06 26.7 0.0 0.011 14.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 CEP13205.1 - 3.6e-06 27.7 0.1 0.024 15.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 CEP13205.1 - 3.8e-06 27.0 0.3 0.048 13.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CEP13205.1 - 4e-06 26.3 0.2 0.025 13.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CEP13205.1 - 6.3e-06 25.6 0.2 0.14 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CEP13205.1 - 1.6e-05 25.0 2.4 0.18 11.9 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CEP13205.1 - 6.7e-05 22.7 0.4 0.19 11.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 CEP13205.1 - 8.5e-05 22.1 0.5 0.35 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 CEP13205.1 - 9.5e-05 21.9 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Miro PF08477.8 CEP13205.1 - 0.0001 22.7 1.2 1.8 9.0 0.0 3.7 3 0 0 3 3 3 1 Miro-like protein DUF87 PF01935.12 CEP13205.1 - 0.00016 21.5 0.4 0.037 13.8 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 CEP13205.1 - 0.00016 21.9 0.1 0.6 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CEP13205.1 - 0.00026 20.6 0.6 0.97 9.1 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CEP13205.1 - 0.0011 18.9 0.6 0.15 12.0 0.1 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 CEP13205.1 - 0.0012 18.3 0.1 7.1 6.0 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_16 PF13191.1 CEP13205.1 - 0.0012 18.8 1.9 0.44 10.4 0.4 2.6 2 1 0 2 2 2 1 AAA ATPase domain Pox_A32 PF04665.7 CEP13205.1 - 0.0017 17.7 0.3 0.7 9.1 0.1 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein DUF258 PF03193.11 CEP13205.1 - 0.0021 17.2 0.1 0.39 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ResIII PF04851.10 CEP13205.1 - 0.0025 17.6 0.0 0.48 10.2 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 CEP13205.1 - 0.0049 15.7 0.2 0.64 8.8 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain Dynamin_N PF00350.18 CEP13205.1 - 0.0061 16.3 0.3 0.9 9.3 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_14 PF13173.1 CEP13205.1 - 0.007 16.2 0.1 2.4 8.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 CEP13205.1 - 0.012 15.3 3.6 1.6 8.3 0.2 3.0 3 0 0 3 3 3 0 NACHT domain ATP_bind_1 PF03029.12 CEP13205.1 - 0.012 15.1 0.8 11 5.4 0.2 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 CEP13205.1 - 0.018 13.7 0.0 5.9 5.3 0.0 2.9 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 CEP13205.1 - 0.019 14.8 0.0 5.4 7.0 0.0 3.1 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 CEP13205.1 - 0.019 14.6 0.7 0.18 11.5 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 CEP13205.1 - 0.019 15.1 0.8 7.8 6.7 0.0 3.4 3 0 0 3 3 3 0 RNA helicase cobW PF02492.14 CEP13205.1 - 0.022 14.2 2.2 0.23 10.8 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 CEP13205.1 - 0.025 14.1 2.4 0.36 10.3 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 CEP13205.1 - 0.047 13.4 0.7 6.2 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CEP13205.1 - 0.048 12.7 0.0 7.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 CEP13205.1 - 0.088 12.4 0.1 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 CEP13205.1 - 0.18 12.0 1.0 9.2 6.4 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CEP13205.1 - 0.19 10.6 0.6 6.3 5.6 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 CEP13205.1 - 0.26 10.7 3.5 6 6.3 0.0 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase TRAP-gamma PF07074.7 CEP13205.1 - 0.53 9.8 9.4 0.022 14.2 1.4 2.5 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) NTPase_1 PF03266.10 CEP13205.1 - 1.1 9.0 2.8 38 3.9 0.1 3.3 3 0 0 3 3 3 0 NTPase RseC_MucC PF04246.7 CEP13205.1 - 2.7 7.5 5.6 0.61 9.6 0.0 2.8 3 0 0 3 3 2 0 Positive regulator of sigma(E), RseC/MucC MaoC_dehydratas PF01575.14 CEP13206.1 - 2.2e-27 94.8 0.0 1.1e-26 92.6 0.0 2.2 1 0 0 1 1 1 1 MaoC like domain SH3_1 PF00018.23 CEP13206.1 - 1.2e-25 88.6 4.5 2.9e-12 45.7 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CEP13206.1 - 3.1e-23 81.1 2.3 1.1e-12 47.3 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 CEP13206.1 - 2e-15 56.8 0.0 4.8e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.12 CEP13206.1 - 1.1e-14 53.6 0.1 1.9e-09 36.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain MIP-T3 PF10243.4 CEP13206.1 - 5.7e-05 21.7 54.9 9.7e-05 21.0 38.0 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 rve PF00665.21 CEP13208.1 - 7.7e-18 64.7 0.0 1.8e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP13208.1 - 9.4e-16 57.8 0.1 2.1e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CEP13208.1 - 0.00042 19.7 0.0 0.0013 18.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 CEP13209.1 - 2.1e-06 27.6 1.3 8.8e-06 25.7 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CEP13211.1 - 5.9e-09 36.3 0.1 1.3e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CEP13211.1 - 4.8e-05 23.3 0.1 8.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CEP13211.1 - 0.00016 21.5 0.0 0.00036 20.3 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CEP13211.1 - 0.00053 19.5 0.0 0.00091 18.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CEP13211.1 - 0.0026 17.1 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CEP13211.1 - 0.0028 17.4 0.1 0.0061 16.3 0.1 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 CEP13211.1 - 0.0077 16.1 2.6 0.013 15.3 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 CEP13212.1 - 1e-13 51.1 0.4 2.2e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 CEP13212.1 - 0.0025 17.1 0.1 0.0063 15.8 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UPF0262 PF06793.7 CEP13212.1 - 0.02 14.5 0.1 0.76 9.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) DUF569 PF04601.8 CEP13212.1 - 0.14 11.6 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF569) Chromo PF00385.19 CEP13213.1 - 8.6e-16 57.3 0.5 1.9e-15 56.2 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CEP13213.1 - 7e-12 45.5 0.1 2e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.3 CEP13213.1 - 0.03 14.0 0.6 0.074 12.7 0.0 1.9 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain SelB-wing_2 PF09106.6 CEP13213.1 - 0.076 12.9 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix zf-CCHC_6 PF15288.1 CEP13216.1 - 0.0062 16.1 6.3 0.55 9.9 0.6 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 CEP13216.1 - 0.016 15.0 0.6 0.016 15.0 0.4 3.0 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 CEP13216.1 - 0.81 9.4 4.6 14 5.5 0.1 2.6 2 1 0 2 2 2 0 Zinc knuckle zf-Mss51 PF13824.1 CEP13216.1 - 1 9.2 5.3 6.9 6.6 0.1 2.5 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CCHC_4 PF14392.1 CEP13216.1 - 1.9 8.2 8.3 3 7.5 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle Exo_endo_phos_2 PF14529.1 CEP13217.1 - 0.059 12.9 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF2635 PF10948.3 CEP13218.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Mito_carr PF00153.22 CEP13219.1 - 2.4e-28 97.6 2.2 1.6e-18 66.1 0.0 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein RNA_pol_Rpb8 PF03870.10 CEP13220.1 - 0.13 12.4 0.1 2.6 8.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase Rpb8 RNase_PH PF01138.16 CEP13221.1 - 2.1e-38 131.5 0.0 3.4e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CEP13221.1 - 5.4e-09 35.8 0.1 8.9e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SAMP PF05924.6 CEP13221.1 - 0.077 12.1 0.1 0.19 10.9 0.1 1.6 1 0 0 1 1 1 0 SAMP Motif Rax2 PF12768.2 CEP13222.1 - 3.2e-69 233.2 23.2 3.5e-53 180.6 3.0 6.2 4 2 2 6 6 6 5 Cortical protein marker for cell polarity SH3_9 PF14604.1 CEP13222.1 - 6e-10 38.5 0.3 1.2e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP13222.1 - 9e-09 34.5 1.6 1e-08 34.3 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CEP13222.1 - 4.8e-06 25.9 0.0 1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.1 CEP13222.1 - 0.00012 22.0 10.2 0.79 9.9 0.0 6.3 6 0 0 6 6 6 2 Kelch motif EphA2_TM PF14575.1 CEP13222.1 - 0.048 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 CEP13222.1 - 0.39 10.2 0.0 0.88 9.1 0.0 1.5 1 0 0 1 1 1 0 IncA protein Piwi PF02171.12 CEP13223.1 - 1.3e-90 303.4 0.1 2e-90 302.8 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CEP13223.1 - 1.3e-23 82.8 0.1 2.4e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CEP13223.1 - 4.8e-12 45.0 0.0 1.7e-11 43.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) MULE PF10551.4 CEP13224.1 - 2.2e-08 34.1 0.7 3.2e-07 30.4 0.2 2.5 1 1 1 2 2 2 1 MULE transposase domain DDE_Tnp_IS240 PF13610.1 CEP13224.1 - 0.053 13.4 1.9 1 9.2 0.0 3.4 4 0 0 4 4 4 0 DDE domain FAR1 PF03101.10 CEP13225.1 - 0.017 15.6 0.2 0.024 15.1 0.1 1.2 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF410 PF04190.8 CEP13225.1 - 0.023 14.2 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF410) Acetyltransf_1 PF00583.19 CEP13226.1 - 6.1e-16 58.2 0.0 7.5e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP13226.1 - 1.2e-06 28.5 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP13226.1 - 1.8e-06 28.0 0.0 2.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP13226.1 - 2.8e-06 26.9 0.1 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CEP13226.1 - 0.00021 21.1 0.4 0.00029 20.6 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP13226.1 - 0.0007 19.7 0.0 0.0008 19.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEP13226.1 - 0.015 15.2 0.0 0.017 15.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1999 PF09390.5 CEP13226.1 - 0.021 14.1 0.1 0.04 13.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1999) Acetyltransf_CG PF14542.1 CEP13226.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 CEP13226.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Xpo1 PF08389.7 CEP13227.1 - 2.8e-14 53.2 1.7 1.5e-12 47.6 0.0 4.2 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CEP13227.1 - 2.7e-08 33.6 3.9 9.6e-07 28.6 2.8 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain KBP_C PF12309.3 CEP13228.1 - 0.059 12.3 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal OrfB_Zn_ribbon PF07282.6 CEP13228.1 - 0.081 12.5 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Kinesin PF00225.18 CEP13231.1 - 3.2e-100 335.1 0.3 3.2e-100 335.1 0.2 2.6 2 1 1 3 3 3 1 Kinesin motor domain AAA_22 PF13401.1 CEP13231.1 - 1.8 8.7 0.0 1.8 8.7 0.0 4.2 4 0 0 4 4 4 0 AAA domain Aldedh PF00171.17 CEP13232.1 - 2e-17 62.6 5.0 1.1e-13 50.3 0.9 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Cu-oxidase PF00394.17 CEP13233.1 - 1.6e-29 102.8 0.1 7.3e-28 97.4 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CEP13233.1 - 8.8e-29 99.6 1.2 2.1e-28 98.3 0.8 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CEP13233.1 - 1.1e-19 70.2 15.0 1.9e-19 69.5 1.9 4.0 3 2 0 3 3 3 1 Multicopper oxidase Copper-bind PF00127.15 CEP13233.1 - 0.025 14.7 0.1 0.29 11.3 0.1 2.5 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Neur_chan_memb PF02932.11 CEP13233.1 - 0.19 11.5 0.8 0.3 10.9 0.3 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Mito_carr PF00153.22 CEP13234.1 - 5.1e-64 212.0 3.1 1.2e-21 76.1 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CEP13234.1 - 1.2e-17 63.7 1.7 1.3e-10 41.2 0.4 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CEP13234.1 - 2.4e-13 48.3 2.9 1.8e-05 23.6 0.9 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CEP13234.1 - 2e-12 46.5 3.9 5.9e-08 32.1 0.6 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP13234.1 - 2.3e-12 45.6 2.6 0.0051 16.5 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_10 PF14788.1 CEP13234.1 - 4.2e-06 26.3 0.5 0.033 13.8 0.0 4.2 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 CEP13234.1 - 0.00017 20.7 2.7 0.014 14.7 0.4 3.3 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 CEP13234.1 - 0.0069 16.3 0.0 0.34 10.9 0.0 2.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Nha1_C PF08619.5 CEP13234.1 - 0.087 12.0 1.4 0.13 11.5 1.0 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus EF-hand_4 PF12763.2 CEP13234.1 - 0.13 11.9 0.1 0.8 9.4 0.0 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand HTH_29 PF13551.1 CEP13237.1 - 3.3e-11 43.2 0.0 8.5e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP13237.1 - 1.8e-08 35.0 0.0 3.8e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP13237.1 - 5.6e-08 32.6 0.1 4.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP13237.1 - 6.1e-08 32.0 0.2 3.2e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 Homeodomain-like domain DDE_3 PF13358.1 CEP13237.1 - 8.7e-08 32.0 0.0 2.1e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_17 PF12728.2 CEP13237.1 - 2.4e-05 24.4 0.0 0.19 12.0 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 CEP13237.1 - 0.0001 22.1 1.1 0.0016 18.3 0.0 2.5 3 0 0 3 3 3 1 Transposase HTH_36 PF13730.1 CEP13237.1 - 0.0072 16.4 0.2 0.075 13.1 0.0 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.1 CEP13237.1 - 0.0076 16.5 0.2 0.041 14.2 0.1 2.1 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.1 CEP13237.1 - 0.011 14.8 0.0 0.024 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 CEP13237.1 - 0.037 13.6 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_11 PF08279.7 CEP13237.1 - 0.042 13.4 0.1 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 HTH domain Sigma70_r4_2 PF08281.7 CEP13237.1 - 0.057 12.8 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_38 PF13936.1 CEP13237.1 - 0.07 12.6 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Uds1 PF15456.1 CEP13238.1 - 3.8e-19 68.8 9.8 3.8e-19 68.8 6.8 7.0 4 2 3 8 8 8 2 Up-regulated During Septation NOT2_3_5 PF04153.13 CEP13239.1 - 6e-30 103.8 1.2 1.1e-29 103.0 0.8 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Mhr1 PF12829.2 CEP13240.1 - 5.4e-07 29.3 0.3 8.3e-07 28.7 0.2 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Caudo_TAP PF02413.12 CEP13240.1 - 0.042 14.0 1.2 0.064 13.4 0.8 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein LigB PF02900.13 CEP13241.1 - 7.1e-45 153.1 0.0 9.7e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NAD_binding_1 PF00175.16 CEP13242.1 - 5.9e-31 107.2 0.0 8.6e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEP13242.1 - 9.9e-31 105.8 0.0 1.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CEP13242.1 - 2.3e-05 24.3 0.0 0.00088 19.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CEP13242.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Rhomboid PF01694.17 CEP13243.1 - 3.4e-21 75.7 7.4 5.8e-21 75.0 5.1 1.3 1 0 0 1 1 1 1 Rhomboid family PAT1 PF09770.4 CEP13244.1 - 0.00012 20.4 50.5 0.00018 19.9 35.0 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CEP13244.1 - 0.18 10.0 74.9 0.019 13.2 48.4 1.7 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CEP13244.1 - 0.38 11.1 35.5 1.3 9.3 20.2 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein BTV_NS2 PF04514.7 CEP13244.1 - 3.1 6.6 27.5 7.1 5.3 19.0 1.6 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Lin-8 PF03353.10 CEP13244.1 - 6.2 6.0 43.2 0.42 9.8 25.5 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Tyr_Deacylase PF02580.11 CEP13245.1 - 0.17 11.8 2.5 0.24 11.3 1.7 1.4 1 1 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase Iron_permease PF04120.7 CEP13245.1 - 4.3 6.9 6.5 8.1 6.0 4.5 1.5 1 0 0 1 1 1 0 Low affinity iron permease GUN4 PF05419.7 CEP13246.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 GUN4-like NfI_DNAbd_pre-N PF10524.4 CEP13247.1 - 0.05 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus NfI_DNAbd_pre-N PF10524.4 CEP13248.1 - 0.025 14.1 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Ribosomal_L18ae PF01775.12 CEP13249.1 - 3.5e-58 194.8 2.4 4.5e-58 194.5 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain GATA PF00320.22 CEP13250.1 - 8.3e-11 41.0 5.7 1.9e-10 39.9 3.9 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-C3HC4_3 PF13920.1 CEP13250.1 - 0.068 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP13250.1 - 0.24 11.4 0.9 0.4 10.7 0.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF605 PF04652.11 CEP13250.1 - 0.28 10.5 32.3 0.56 9.5 8.3 2.2 2 0 0 2 2 2 0 Vta1 like Cytadhesin_P30 PF07271.6 CEP13250.1 - 1.4 8.1 34.9 0.18 11.0 1.3 3.8 3 1 0 3 3 3 0 Cytadhesin P30/P32 IFT43 PF15305.1 CEP13254.1 - 0.43 10.5 4.1 0.52 10.3 2.9 1.1 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Mucin PF01456.12 CEP13254.1 - 5.8 6.6 15.8 6.7 6.4 11.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1604 PF07713.8 CEP13255.1 - 2.1 8.2 4.5 3.3 7.5 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1604) Exo_endo_phos_2 PF14529.1 CEP13256.1 - 1.7e-16 59.8 0.6 4.9e-16 58.4 0.4 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP13256.1 - 4e-05 23.6 0.7 7.3e-05 22.8 0.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CEP13257.1 - 2.8e-09 36.6 0.0 1e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prismane PF03063.15 CEP13257.1 - 0.28 9.5 0.4 0.39 9.0 0.3 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family THP2 PF09432.5 CEP13257.1 - 1.5 8.6 5.7 1.1 9.1 0.1 2.9 3 0 0 3 3 3 0 Tho complex subunit THP2 DUF1180 PF06679.7 CEP13258.1 - 1.3e-05 25.0 0.2 1.3e-05 25.0 0.1 3.2 1 1 1 4 4 4 1 Protein of unknown function (DUF1180) DUF1191 PF06697.7 CEP13258.1 - 2.2e-05 23.4 0.0 3.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF912 PF06024.7 CEP13258.1 - 0.34 11.0 0.0 0.34 11.0 0.0 3.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 CEP13258.1 - 0.5 10.7 0.1 0.5 10.7 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Serinc PF03348.10 CEP13258.1 - 2.8 6.5 3.9 2.9 6.4 0.9 1.9 1 1 1 2 2 2 0 Serine incorporator (Serinc) WD40 PF00400.27 CEP13259.1 - 1.6e-05 24.5 0.6 0.88 9.5 0.0 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat SR-25 PF10500.4 CEP13259.1 - 0.098 12.1 12.0 0.19 11.1 8.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.2 CEP13260.1 - 5.5e-21 74.7 0.1 2.9e-12 46.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEP13260.1 - 2.3e-19 68.1 0.0 6.7e-10 38.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CEP13260.1 - 1.2e-17 63.4 0.1 2.9e-11 43.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP13260.1 - 2.4e-14 53.3 0.0 1.6e-06 28.4 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP13260.1 - 5e-14 51.0 0.0 3.4e-07 29.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Phage_Gp111 PF07410.6 CEP13260.1 - 0.082 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein LIM PF00412.17 CEP13261.1 - 8e-29 99.4 72.2 1.5e-09 37.8 6.0 5.9 5 1 0 5 5 5 5 LIM domain DUF2175 PF09943.4 CEP13261.1 - 9.4 6.3 13.8 16 5.6 2.6 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) KH_1 PF00013.24 CEP13262.1 - 2.1e-43 145.7 7.3 8.6e-17 60.5 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CEP13262.1 - 1.8e-31 107.1 11.7 3.4e-11 42.5 0.9 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CEP13262.1 - 4.1e-11 42.2 8.4 0.0036 16.8 0.2 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 CEP13262.1 - 1.3e-07 31.1 1.8 0.44 10.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CEP13262.1 - 0.00032 20.4 5.2 0.71 9.7 0.0 3.6 4 0 0 4 4 4 2 NusA-like KH domain EII-Sor PF03609.9 CEP13262.1 - 0.094 11.9 1.9 0.13 11.5 1.3 1.1 1 0 0 1 1 1 0 PTS system sorbose-specific iic component Kri1_C PF12936.2 CEP13263.1 - 7e-30 102.8 3.7 7e-30 102.8 2.6 4.3 2 2 2 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 CEP13263.1 - 3e-24 85.1 8.4 3e-24 85.1 5.8 5.1 5 1 1 6 6 6 1 KRI1-like family Pkinase PF00069.20 CEP13264.1 - 1.5e-51 175.1 0.0 2.1e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TB2_DP1_HVA22 PF03134.14 CEP13264.1 - 2.8e-34 116.7 6.8 4.8e-34 115.9 4.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pkinase_Tyr PF07714.12 CEP13264.1 - 5.7e-28 97.6 0.0 9.6e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP13264.1 - 0.00068 18.7 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosom_S12_S23 PF00164.20 CEP13265.1 - 8.6e-41 138.1 0.8 1e-40 137.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Chitin_synth_2 PF03142.10 CEP13266.1 - 3.7e-272 903.4 0.0 6e-272 902.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 CEP13266.1 - 2.2e-19 70.1 0.0 4.5e-17 62.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEP13266.1 - 6.5e-18 65.1 0.8 2.1e-17 63.4 0.6 2.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 CEP13266.1 - 8.5e-06 25.1 0.0 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CEP13266.1 - 0.0013 18.4 0.0 0.0079 15.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 YEATS PF03366.11 CEP13267.1 - 1.3e-20 72.8 0.1 3.4e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 YEATS family SR-25 PF10500.4 CEP13267.1 - 0.002 17.6 4.1 0.0026 17.2 2.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein E1-E2_ATPase PF00122.15 CEP13268.1 - 2.7e-58 196.7 9.9 9.1e-57 191.7 5.8 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEP13268.1 - 4e-29 102.5 0.8 1e-28 101.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP13268.1 - 9.2e-15 55.3 0.0 2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP13268.1 - 3.7e-14 51.9 0.0 2.2e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 CEP13268.1 - 0.0012 18.4 6.2 0.0012 18.4 4.3 2.6 2 2 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 CEP13268.1 - 0.013 15.0 0.2 0.035 13.6 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP13268.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit PsiA PF06952.6 CEP13268.1 - 0.081 11.9 0.3 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 PsiA protein Perilipin PF03036.11 CEP13269.1 - 3.4e-11 42.6 16.5 4.7e-09 35.5 11.5 2.2 1 1 0 1 1 1 1 Perilipin family Apolipoprotein PF01442.13 CEP13269.1 - 0.017 14.6 17.7 0.087 12.3 0.6 3.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Aldo_ket_red PF00248.16 CEP13270.1 - 1.7e-48 164.9 0.0 1.9e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_trans PF01144.18 CEP13270.1 - 0.086 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase DnaJ PF00226.26 CEP13271.1 - 2.7e-24 84.6 0.4 2.7e-24 84.6 0.3 3.1 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.3 CEP13271.1 - 8e-11 41.7 8.4 6.7e-10 38.8 2.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP13271.1 - 5e-08 32.8 3.0 5e-08 32.8 2.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CEP13271.1 - 5.2e-07 29.7 5.2 0.011 15.8 0.5 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CEP13271.1 - 0.00029 20.9 1.6 0.78 10.2 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP13271.1 - 0.00051 20.2 5.5 0.15 12.4 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-RVT PF13966.1 CEP13271.1 - 0.086 13.1 0.4 0.086 13.1 0.3 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF678 PF05077.7 CEP13271.1 - 8 6.5 8.5 20 5.2 2.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF678) VCBS PF13517.1 CEP13272.1 - 3.9e-29 100.7 18.7 5.1e-09 36.3 0.2 5.7 2 2 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CEP13272.1 - 2.3e-16 58.9 19.6 0.00028 20.4 0.6 7.3 7 0 0 7 7 7 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 CEP13272.1 - 2.6e-06 26.9 5.5 0.16 11.4 0.0 5.6 4 1 1 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region EF-hand_1 PF00036.27 CEP13272.1 - 4.2 6.9 5.9 7 6.2 0.3 3.4 3 0 0 3 3 3 0 EF hand RrnaAD PF00398.15 CEP13273.1 - 1.4e-17 63.6 0.0 1.8e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CBM_5_12 PF02839.9 CEP13274.1 - 2.2e-07 30.3 1.6 2.2e-07 30.3 1.1 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain C2 PF00168.25 CEP13274.1 - 9.4e-07 28.5 0.2 5e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 C2 domain DUF1510 PF07423.6 CEP13274.1 - 2.3e-05 23.8 12.0 5.2e-05 22.7 8.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) IncA PF04156.9 CEP13274.1 - 0.00027 20.5 0.3 0.00043 19.9 0.2 1.2 1 0 0 1 1 1 1 IncA protein DUF4366 PF14283.1 CEP13274.1 - 0.0044 16.4 3.5 0.0044 16.4 2.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4366) DUF533 PF04391.7 CEP13274.1 - 0.0047 16.3 0.3 0.0084 15.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF533) HemX PF04375.9 CEP13274.1 - 0.0086 14.7 0.8 0.012 14.2 0.6 1.1 1 0 0 1 1 1 1 HemX OmpH PF03938.9 CEP13274.1 - 0.54 10.1 9.4 0.91 9.4 6.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MIP-T3 PF10243.4 CEP13274.1 - 1.1 7.6 19.5 1.6 7.1 13.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NARP1 PF12569.3 CEP13274.1 - 3.4 6.3 18.3 5 5.7 12.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vma12 PF11712.3 CEP13274.1 - 4 7.1 8.8 7.6 6.2 6.1 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_M24 PF00557.19 CEP13275.1 - 2.5e-23 82.7 0.1 2.8e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Glycohydro_20b2 PF14845.1 CEP13275.1 - 0.036 14.7 0.1 0.1 13.2 0.0 1.9 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like PUF PF00806.14 CEP13277.1 - 8.3e-60 195.0 16.2 7.1e-08 31.5 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNB PF00773.14 CEP13278.1 - 5.2e-99 331.6 0.3 1.9e-98 329.7 0.0 1.9 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 CEP13278.1 - 0.00013 21.4 0.1 0.00054 19.4 0.1 2.1 2 0 0 2 2 2 1 Ribonuclease B OB domain Plus-3 PF03126.13 CEP13279.1 - 0.088 12.8 1.2 0.14 12.1 0.7 1.5 1 1 0 1 1 1 0 Plus-3 domain S10_plectin PF03501.10 CEP13279.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Plectin/S10 domain RasGEF PF00617.14 CEP13281.1 - 5.2e-13 49.1 1.3 6.4e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain PAM2 PF07145.10 CEP13281.1 - 0.0035 16.7 0.0 0.012 15.0 0.0 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region SSP160 PF06933.6 CEP13281.1 - 2.3 6.1 18.3 3.8 5.3 12.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Bromodomain PF00439.20 CEP13282.1 - 5.7e-23 80.6 0.2 5.7e-23 80.6 0.1 2.4 3 0 0 3 3 3 1 Bromodomain Myb_DNA-binding PF00249.26 CEP13282.1 - 0.07 13.2 0.1 0.07 13.2 0.1 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain SNARE_assoc PF09335.6 CEP13283.1 - 4.4e-12 46.2 5.8 4.4e-12 46.2 4.0 1.8 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF3329 PF11808.3 CEP13283.1 - 0.079 13.0 0.4 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) FAD_binding_1 PF00667.15 CEP13284.1 - 7.5e-62 208.6 0.0 1.3e-61 207.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.14 CEP13284.1 - 8.4e-27 94.1 2.8 1.4e-26 93.4 2.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_1 PF00175.16 CEP13284.1 - 1.1e-13 51.7 0.0 4.8e-13 49.6 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEP13284.1 - 0.048 13.7 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Mito_carr PF00153.22 CEP13285.1 - 7.7e-43 144.1 5.6 1.5e-15 56.6 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein BCAS3 PF12490.3 CEP13286.1 - 6e-10 38.8 1.3 6e-10 38.8 0.9 4.0 6 0 0 6 6 6 1 Breast carcinoma amplified sequence 3 WD40 PF00400.27 CEP13286.1 - 0.0024 17.6 2.7 0.0029 17.4 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat APC_CDC26 PF10471.4 CEP13286.1 - 0.52 11.0 32.0 0.87 10.3 0.3 5.1 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 MPC PF03650.8 CEP13287.1 - 9e-18 64.3 0.1 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Glyco_transf_49 PF13896.1 CEP13288.1 - 3.4e-11 42.8 0.0 0.00019 20.6 0.0 2.4 2 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan Glyoxal_oxid_N PF07250.6 CEP13288.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Ribonuc_P_40 PF08584.6 CEP13289.1 - 0.023 13.6 0.0 0.026 13.5 0.0 1.0 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Ceramidase PF05875.7 CEP13290.1 - 3.4e-45 154.2 18.8 1e-38 132.9 4.9 2.0 1 1 1 2 2 2 2 Ceramidase Polysacc_synt_C PF14667.1 CEP13290.1 - 0.25 11.1 7.1 4.3 7.1 0.7 2.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain SdpI PF13630.1 CEP13290.1 - 0.26 11.0 2.2 0.88 9.3 1.5 1.8 1 0 0 1 1 1 0 SdpI/YhfL protein family Gti1_Pac2 PF09729.4 CEP13291.1 - 9.5e-47 158.9 9.4 6.9e-39 133.3 0.1 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family Cullin PF00888.17 CEP13293.1 - 8.4e-24 84.0 0.1 2.4e-23 82.5 0.0 1.7 2 0 0 2 2 2 1 Cullin family Chitin_synth_2 PF03142.10 CEP13294.1 - 2.3e-280 930.4 0.4 3.3e-280 929.9 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 CEP13294.1 - 1.3e-18 67.6 0.0 1.2e-16 61.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEP13294.1 - 4.1e-17 62.5 0.9 1.1e-16 61.1 0.6 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CEP13294.1 - 4.4e-06 26.4 0.0 0.00032 20.4 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP13294.1 - 0.00093 18.5 0.0 0.005 16.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 BAR PF03114.13 CEP13295.1 - 1.4e-32 113.0 4.7 2.1e-32 112.5 3.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CEP13295.1 - 4.2e-14 51.6 0.1 8.5e-14 50.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP13295.1 - 9.8e-13 47.4 0.2 9.8e-13 47.4 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CEP13295.1 - 4.2e-12 45.3 0.0 8.5e-12 44.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF489 PF04356.7 CEP13295.1 - 0.83 9.2 7.7 4.7 6.7 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF489) GAS PF13851.1 CEP13295.1 - 1.4 8.0 12.9 0.072 12.2 1.4 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TMEM192 PF14802.1 CEP13296.1 - 0.14 11.0 0.1 0.14 11.0 0.0 1.3 2 0 0 2 2 2 0 TMEM192 family UDPG_MGDP_dh_N PF03721.9 CEP13297.1 - 8.3e-63 211.1 0.6 1.9e-62 209.9 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 CEP13297.1 - 2.1e-35 121.0 0.4 2.2e-33 114.5 0.2 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 CEP13297.1 - 5.6e-31 106.6 0.0 1.7e-30 105.0 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 CEP13297.1 - 5.6e-05 22.9 0.2 0.0037 17.0 0.0 2.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OTCace PF00185.19 CEP13297.1 - 0.002 18.0 0.1 0.66 9.8 0.0 2.5 2 0 0 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NAD_binding_2 PF03446.10 CEP13297.1 - 0.0043 16.9 0.0 0.17 11.7 0.0 2.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CEP13297.1 - 0.009 16.4 1.3 3.5 8.1 0.0 3.5 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 CEP13297.1 - 0.01 15.6 0.6 3.4 7.4 0.0 3.2 2 2 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain AAA-ATPase_like PF09820.4 CEP13297.1 - 0.016 14.4 1.1 0.025 13.7 0.8 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase 3HCDH_N PF02737.13 CEP13297.1 - 0.063 12.9 0.2 0.4 10.3 0.0 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Med18 PF09637.5 CEP13298.1 - 1.4e-22 80.4 0.0 6.7e-21 74.9 0.0 2.0 1 1 0 1 1 1 1 Med18 protein DUF4503 PF14951.1 CEP13298.1 - 0.037 12.1 0.1 0.21 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4503) Glyoxalase PF00903.20 CEP13299.1 - 1.4e-21 76.7 1.6 1.2e-16 60.8 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 CEP13299.1 - 1e-12 47.9 0.2 1.2e-05 25.3 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CEP13299.1 - 5.8e-09 36.5 0.1 0.00079 20.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 CEP13299.1 - 2.5e-08 33.9 0.0 5.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 CEP13299.1 - 7.5e-05 22.7 0.1 0.049 13.5 0.1 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain Ribosomal_L35Ae PF01247.13 CEP13300.1 - 1.6e-41 139.9 1.3 1.8e-41 139.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CEP13300.1 - 0.0026 17.6 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.20 CEP13301.1 - 1.9e-13 50.1 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13301.1 - 1.1e-08 34.4 0.0 1.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Tyr-DNA_phospho PF06087.7 CEP13302.1 - 3.9e-47 160.9 0.0 2.3e-46 158.3 0.0 1.9 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 CEP13302.1 - 1.1e-07 31.6 0.0 0.0015 18.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 CEP13302.1 - 0.003 16.9 0.9 0.0092 15.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin interaction motif WD40 PF00400.27 CEP13304.1 - 2.1e-13 49.6 3.0 0.00095 18.9 0.5 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat TFIIB PF00382.14 CEP13305.1 - 2.7e-44 148.8 3.7 2.2e-23 81.8 1.3 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CEP13305.1 - 5.9e-15 54.3 0.6 1.3e-14 53.2 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 CEP13305.1 - 0.0023 17.8 1.4 0.097 12.6 0.0 2.3 1 1 0 2 2 2 1 Cyclin, C-terminal domain HTH_5 PF01022.15 CEP13305.1 - 0.019 14.5 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Trp_repressor PF01371.14 CEP13305.1 - 0.04 13.8 0.1 16 5.4 0.0 2.7 2 0 0 2 2 2 0 Trp repressor protein Cyclin_N PF00134.18 CEP13305.1 - 0.063 12.8 1.7 0.5 9.9 0.2 2.2 1 1 1 2 2 2 0 Cyclin, N-terminal domain Bromodomain PF00439.20 CEP13306.1 - 5e-17 61.5 1.1 1.3e-16 60.2 0.8 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 CEP13306.1 - 1.6e-09 37.3 0.0 5.5e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated Tim17 PF02466.14 CEP13307.1 - 9.8e-36 122.6 6.0 1.2e-35 122.3 4.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.1 CEP13307.1 - 0.0099 15.7 2.5 0.28 11.0 1.8 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4235) RAB3GAP2_N PF14655.1 CEP13308.1 - 5.2e-65 220.0 0.0 1.3e-64 218.7 0.0 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Lsm_interact PF05391.6 CEP13308.1 - 3.6e-05 22.9 0.7 0.00018 20.7 0.5 2.3 1 0 0 1 1 1 1 Lsm interaction motif TPR_14 PF13428.1 CEP13308.1 - 0.0037 17.7 1.1 0.88 10.3 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP13308.1 - 0.0086 16.4 2.8 0.49 10.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP13308.1 - 0.059 13.5 0.9 4.2 7.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Dus PF01207.12 CEP13309.1 - 2e-73 246.9 0.0 2.9e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 CEP13309.1 - 0.022 13.7 0.0 0.06 12.2 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase IMPDH PF00478.20 CEP13309.1 - 0.047 12.5 0.1 0.083 11.7 0.1 1.5 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Methyltransf_23 PF13489.1 CEP13310.1 - 4.7e-12 45.9 0.0 9.5e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP13310.1 - 6.6e-11 42.5 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP13310.1 - 1.8e-07 30.4 0.0 4.6e-06 25.8 0.0 2.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CEP13310.1 - 3.3e-07 30.0 0.0 9.7e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP13310.1 - 1.3e-06 28.7 0.0 2.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP13310.1 - 1.6e-06 28.4 0.0 5.1e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP13310.1 - 1e-05 24.7 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CEP13310.1 - 6.4e-05 23.5 0.0 0.00031 21.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CEP13310.1 - 0.011 15.7 0.1 0.037 14.0 0.0 1.8 1 1 1 2 2 2 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CEP13310.1 - 0.025 14.6 0.0 0.06 13.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 CEP13310.1 - 0.025 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CEP13310.1 - 0.058 12.4 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 CEP13310.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Gaa1 PF04114.9 CEP13311.1 - 1.4e-73 248.3 19.2 3.1e-72 243.9 13.3 2.6 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component GST_N_3 PF13417.1 CEP13312.1 - 4.2e-14 52.5 0.1 1.8e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP13312.1 - 5.1e-08 32.7 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP13312.1 - 3.8e-07 30.1 0.0 8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEP13312.1 - 7.3e-06 25.8 1.1 2.5e-05 24.1 0.2 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEP13312.1 - 0.00076 19.3 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP13312.1 - 0.0081 16.6 0.1 0.025 15.0 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.1 CEP13312.1 - 0.04 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_S7 PF00177.16 CEP13313.1 - 2.8e-39 134.0 0.3 3.3e-39 133.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e VRR_NUC PF08774.6 CEP13314.1 - 6.6e-16 58.1 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain DUF3582 PF12122.3 CEP13315.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3582) Toxin_59 PF15537.1 CEP13315.1 - 0.18 11.9 0.3 0.49 10.4 0.2 1.7 1 1 0 1 1 1 0 Putative toxin 59 zf-C3HC PF07967.8 CEP13322.1 - 3.3e-17 62.5 7.1 6.5e-15 55.0 0.4 2.9 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 CEP13322.1 - 8e-15 54.4 2.0 2.8e-10 39.8 0.1 2.6 2 0 0 2 2 2 2 Rsm1-like Myb_Cef PF11831.3 CEP13322.1 - 0.12 11.5 3.9 0.27 10.4 2.7 1.5 1 0 0 1 1 1 0 pre-mRNA splicing factor component zf-RVT PF13966.1 CEP13324.1 - 2.4e-07 30.9 1.2 4.7e-07 30.0 0.8 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Nup153 PF08604.5 CEP13324.1 - 0.03 12.9 4.6 0.03 13.0 2.9 1.3 1 1 0 1 1 1 0 Nucleoporin Nup153-like DNA_pol_A_exo1 PF01612.15 CEP13325.1 - 1.6e-10 40.7 0.0 3.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PIF1 PF05970.9 CEP13326.1 - 3.8e-13 49.1 0.0 4.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase DUF2009 PF09418.5 CEP13327.1 - 5.6e-191 635.2 0.1 7.6e-191 634.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CEP13327.1 - 3.8e-06 26.6 6.6 8.9e-06 25.5 4.6 1.6 1 0 0 1 1 1 1 B-box zinc finger 4HB_MCP_1 PF12729.2 CEP13327.1 - 0.015 14.6 2.4 0.021 14.1 0.2 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction zf-C3HC4_3 PF13920.1 CEP13327.1 - 0.21 11.2 5.3 0.45 10.2 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP13327.1 - 0.32 11.0 5.8 0.82 9.7 4.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CEP13328.1 - 7.6e-47 158.9 0.0 8.9e-46 155.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP13328.1 - 2e-26 91.6 0.0 5.5e-26 90.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CEP13328.1 - 0.0097 14.3 0.0 0.0097 14.3 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 CEP13328.1 - 0.25 10.4 0.0 0.25 10.4 0.0 4.0 4 1 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Vfa1 PF08432.5 CEP13328.1 - 9.2 6.2 24.7 18 5.3 17.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec23_trunk PF04811.10 CEP13329.1 - 3.3e-74 249.2 0.0 5.1e-74 248.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CEP13329.1 - 2.8e-23 81.3 0.1 5.5e-23 80.3 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CEP13329.1 - 1.1e-17 63.2 2.7 2e-17 62.4 1.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CEP13329.1 - 1.7e-16 60.4 0.0 3.9e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CEP13329.1 - 9.6e-09 34.8 0.0 2.6e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.1 CEP13329.1 - 0.023 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.23 CEP13329.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain 5-FTHF_cyc-lig PF01812.15 CEP13330.1 - 6.4e-27 94.5 0.6 4.7e-26 91.7 0.0 1.9 1 1 1 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family Mucin PF01456.12 CEP13331.1 - 0.28 10.9 26.3 1 9.0 16.7 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein THF_DHG_CYH PF00763.18 CEP13332.1 - 7e-20 71.2 0.1 1.4e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CEP13332.1 - 6.3e-16 57.8 0.1 2.4e-13 49.4 0.1 3.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 CEP13332.1 - 0.038 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle TrkA_C PF02080.16 CEP13332.1 - 0.1 12.2 0.1 0.84 9.2 0.0 2.5 2 1 0 2 2 2 0 TrkA-C domain KH_1 PF00013.24 CEP13333.1 - 1.1e-05 24.9 0.9 2.6e-05 23.7 0.7 1.6 1 0 0 1 1 1 1 KH domain LSM PF01423.17 CEP13334.1 - 9.2e-18 63.5 0.2 1.1e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Mu-like_Com PF10122.4 CEP13334.1 - 0.096 11.7 0.3 0.21 10.6 0.2 1.6 1 1 0 1 1 1 0 Mu-like prophage protein Com Cytochrom_C1 PF02167.10 CEP13335.1 - 6.6e-87 290.7 0.0 9.5e-87 290.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CEP13335.1 - 0.00037 20.5 0.0 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CEP13335.1 - 0.04 14.7 1.5 0.071 13.9 0.3 2.2 2 1 0 2 2 2 0 Cytochrome c Apc1 PF12859.2 CEP13336.1 - 6.8e-09 35.9 0.0 1.6e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 CEP13336.1 - 0.00076 19.5 4.7 2.6 8.4 0.0 5.6 5 0 0 5 5 5 1 Proteasome/cyclosome repeat RNA_pol_N PF01194.12 CEP13337.1 - 4e-31 106.8 0.3 4.5e-31 106.6 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 CEP13338.1 - 3.9e-28 96.2 1.8 8.7e-09 34.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF663 PF04950.7 CEP13339.1 - 3.3e-100 334.9 0.1 5.8e-100 334.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CEP13339.1 - 3.5e-25 87.3 0.0 8e-25 86.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain zf-C3H1 PF10650.4 CEP13342.1 - 1.9e-05 23.9 0.1 3.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain RXT2_N PF08595.6 CEP13343.1 - 1.2e-10 41.4 0.1 1.2e-10 41.4 0.1 3.9 2 2 2 4 4 4 2 RXT2-like, N-terminal DUF4196 PF13846.1 CEP13343.1 - 0.27 11.5 11.0 0.22 11.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) DUF1625 PF07787.7 CEP13344.1 - 0.074 12.2 3.7 0.085 12.0 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) zf-H2C2_2 PF13465.1 CEP13345.1 - 1.5e-11 43.9 18.7 2.9e-06 27.2 1.7 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP13345.1 - 9.6e-09 35.0 23.1 0.00029 20.9 1.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP13345.1 - 2.8e-07 30.4 21.0 0.00034 20.7 0.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger SCHIP-1 PF10148.4 CEP13345.1 - 0.046 13.1 0.4 0.078 12.3 0.3 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 PRA-CH PF01502.13 CEP13345.1 - 0.059 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase TALPID3 PF15324.1 CEP13345.1 - 5 4.3 10.6 3.9 4.7 6.7 1.3 1 1 0 1 1 1 0 Hedgehog signalling target Arf PF00025.16 CEP13346.1 - 5.2e-64 214.6 0.0 5.8e-64 214.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CEP13346.1 - 6e-10 38.6 0.0 7.7e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CEP13346.1 - 1.6e-08 33.6 0.1 3.5e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CEP13346.1 - 2.5e-08 33.5 0.0 3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP13346.1 - 7.3e-08 32.9 0.0 1e-07 32.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEP13346.1 - 1.4e-06 28.2 0.0 4e-06 26.7 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEP13346.1 - 3.2e-06 26.4 0.0 3.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP13346.1 - 0.0067 15.8 0.0 0.25 10.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CEP13346.1 - 0.014 14.8 0.0 0.045 13.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 CEP13346.1 - 0.089 12.0 0.0 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) MobB PF03205.9 CEP13346.1 - 0.11 12.1 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Actin PF00022.14 CEP13347.1 - 1.9e-51 174.7 0.0 3.9e-51 173.7 0.0 1.5 1 1 1 2 2 2 1 Actin MreB_Mbl PF06723.8 CEP13347.1 - 2.4e-14 52.6 0.0 5e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Exo_endo_phos PF03372.18 CEP13348.1 - 4.2e-24 85.8 0.1 7e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 CEP13348.1 - 1.2e-08 34.6 0.1 5.1e-08 32.6 0.1 2.1 1 0 0 1 1 1 1 RhoGAP domain PapD-like PF14874.1 CEP13348.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like DSPc PF00782.15 CEP13349.1 - 2.3e-24 85.4 0.5 2.3e-24 85.4 0.4 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 CEP13349.1 - 2.4e-11 43.9 0.0 2.4e-09 37.5 0.0 3.0 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 CEP13349.1 - 9.6e-05 21.8 0.1 0.00019 20.8 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CEP13349.1 - 0.0003 20.8 0.0 0.00074 19.5 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 CEP13349.1 - 0.009 15.3 0.2 0.021 14.2 0.1 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family 3H PF02829.9 CEP13349.1 - 0.0099 15.8 0.1 0.027 14.4 0.1 1.8 1 0 0 1 1 1 1 3H domain Y_phosphatase3 PF13350.1 CEP13349.1 - 0.015 15.5 0.2 0.062 13.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF4160 PF13711.1 CEP13349.1 - 0.046 13.5 0.5 3.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) IF4E PF01652.13 CEP13350.1 - 9.8e-57 191.0 0.4 1.2e-56 190.8 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HTH_23 PF13384.1 CEP13352.1 - 0.045 13.4 0.1 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1_2 PF13022.1 CEP13352.1 - 0.088 12.6 0.2 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase LZ_Tnp_IS481 PF13011.1 CEP13352.1 - 0.13 12.5 0.3 0.21 11.9 0.1 1.5 1 1 0 1 1 1 0 leucine-zipper of insertion element IS481 TMEM247 PF15444.1 CEP13353.1 - 0.028 14.2 3.0 0.97 9.2 2.1 2.0 1 1 0 1 1 1 0 Transmembrane protein 247 MAP7 PF05672.6 CEP13353.1 - 1.2 8.4 5.0 0.2 11.0 0.8 1.6 2 1 0 2 2 2 0 MAP7 (E-MAP-115) family Hat1_N PF10394.4 CEP13354.1 - 2.4e-40 138.2 1.8 5.7e-40 137.0 1.3 1.7 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.13 CEP13354.1 - 0.00028 20.1 2.2 0.00078 18.7 0.3 2.0 2 0 0 2 2 2 1 MOZ/SAS family Acetyltransf_1 PF00583.19 CEP13354.1 - 0.0081 16.1 0.0 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family HCMV_UL139 PF12507.3 CEP13354.1 - 4.7 7.3 7.3 3.5 7.8 1.5 3.1 3 1 0 3 3 3 0 Human Cytomegalovirus UL139 protein Chitin_synth_2 PF03142.10 CEP13356.1 - 1.3e-232 772.9 2.4 2.2e-232 772.1 1.7 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP13356.1 - 5.8e-16 58.7 3.3 1.8e-15 57.1 2.3 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP13356.1 - 3e-13 50.1 0.0 1.5e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CEP13356.1 - 6.6e-05 22.2 0.1 0.00062 19.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 CEP13356.1 - 0.00021 21.0 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CEP13356.1 - 0.00057 19.6 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1183 PF06682.7 CEP13356.1 - 0.017 14.7 1.0 0.069 12.7 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1183) DDE_3 PF13358.1 CEP13357.1 - 2.1e-08 34.0 0.0 2.2e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HMG_box PF00505.14 CEP13358.1 - 6.2e-25 87.2 2.0 1e-24 86.5 1.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP13358.1 - 2.7e-18 66.0 2.4 2.7e-18 66.0 1.7 1.4 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 CEP13358.1 - 0.0018 18.0 3.2 0.0021 17.8 2.0 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box 5 Imm35 PF15581.1 CEP13358.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 35 Btz PF09405.5 CEP13358.1 - 0.63 10.0 3.9 1.6 8.8 2.7 1.6 1 1 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Neugrin PF06413.6 CEP13359.1 - 7.3e-08 32.5 0.7 7.3e-08 32.5 0.5 1.7 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 CEP13359.1 - 8e-05 22.6 0.5 8e-05 22.6 0.4 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Mannosyl_trans3 PF11051.3 CEP13360.1 - 2.3e-44 151.7 0.4 1.6e-43 149.0 0.2 2.5 1 1 0 1 1 1 1 Mannosyltransferase putative NAD_binding_4 PF07993.7 CEP13360.1 - 4.1e-32 111.0 0.0 6.8e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CEP13360.1 - 1.4e-07 31.2 0.0 1e-06 28.3 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Acyltransferase PF01553.16 CEP13360.1 - 3.7e-06 26.4 0.0 9.2e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase Polysacc_synt_2 PF02719.10 CEP13360.1 - 0.0061 15.4 0.2 0.78 8.5 0.1 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CEP13360.1 - 0.085 11.5 1.0 1.4 7.5 0.7 2.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CEP13360.1 - 0.24 11.3 0.0 0.92 9.4 0.0 2.0 1 0 0 1 1 1 0 NADH(P)-binding BPL_N PF09825.4 CEP13361.1 - 3.5e-99 332.0 0.0 4.3e-99 331.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CEP13361.1 - 8e-18 64.6 0.0 1.4e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CEP13361.1 - 4.5e-06 26.2 0.0 8.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DNA_pol_A_exo1 PF01612.15 CEP13362.1 - 3.6e-18 65.6 0.0 1.2e-17 63.9 0.0 1.9 1 0 0 1 1 1 1 3'-5' exonuclease IBR PF01485.16 CEP13362.1 - 4.6e-18 64.8 47.3 5.2e-10 39.0 5.9 4.4 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 CEP13362.1 - 5.6e-05 23.0 9.9 5.6e-05 23.0 6.9 4.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP13362.1 - 0.00013 21.5 7.1 0.00013 21.5 4.9 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP13362.1 - 0.00032 20.4 6.7 0.00032 20.4 4.7 4.2 2 1 1 3 3 3 1 Ring finger domain Zn_Tnp_IS91 PF14319.1 CEP13362.1 - 0.0057 16.1 1.6 0.0057 16.1 1.1 3.7 2 1 1 3 3 3 1 Transposase zinc-binding domain IFT20 PF14931.1 CEP13362.1 - 0.011 15.5 1.4 0.052 13.4 1.0 2.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 CHCH PF06747.8 CEP13363.1 - 2.6e-09 36.7 6.5 3.6e-09 36.2 4.5 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CEP13363.1 - 0.008 16.1 3.7 0.029 14.4 2.6 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CEP13363.1 - 0.01 15.5 2.2 0.018 14.8 1.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CEP13363.1 - 0.092 12.7 3.3 2.6 8.1 0.3 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 CEP13363.1 - 0.18 11.7 2.6 0.49 10.2 0.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) adh_short PF00106.20 CEP13364.1 - 3.9e-25 88.7 0.0 5.5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEP13364.1 - 2.2e-11 43.7 0.0 3.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CEP13364.1 - 2.1e-08 34.2 0.0 3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CEP13364.1 - 0.00031 20.2 0.0 0.00055 19.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 CEP13364.1 - 0.0024 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.14 CEP13364.1 - 0.0024 16.6 0.0 0.0044 15.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CEP13364.1 - 0.024 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 CEP13364.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 CEP13364.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PGP_phosphatase PF09419.5 CEP13365.1 - 5.3e-48 162.5 0.0 6.6e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 CEP13365.1 - 0.0068 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Isochorismatase PF00857.15 CEP13368.1 - 0.048 13.6 0.3 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Isochorismatase family Mem_trans PF03547.13 CEP13368.1 - 0.071 11.3 0.2 0.071 11.3 0.2 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF2457 PF10446.4 CEP13368.1 - 0.28 9.8 12.8 0.51 9.0 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Med15_fungi PF05397.7 CEP13369.1 - 1.8e-21 76.2 0.5 1.8e-21 76.2 0.4 7.6 7 3 2 9 9 9 1 Mediator complex subunit 15 Mtc PF03820.12 CEP13370.1 - 9.3e-94 313.5 2.1 1.1e-93 313.2 1.4 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Aminotran_1_2 PF00155.16 CEP13371.1 - 3.7e-26 91.9 0.0 4.7e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II IlvN PF07991.7 CEP13371.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain zf-RING_3 PF14369.1 CEP13372.1 - 0.048 13.6 0.2 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 zinc-finger COG2 PF06148.6 CEP13373.1 - 0.041 13.7 0.1 0.099 12.5 0.1 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L2_C PF03947.13 CEP13374.1 - 2.4e-42 143.7 2.1 2.4e-42 143.7 1.4 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CEP13374.1 - 7.8e-16 57.8 0.1 1.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MAS20 PF02064.10 CEP13375.1 - 5.6e-21 74.7 1.6 2.8e-20 72.4 0.5 2.5 2 1 0 2 2 2 1 MAS20 protein import receptor zf-MYND PF01753.13 CEP13375.1 - 0.00035 20.3 8.2 0.00057 19.6 5.7 1.3 1 0 0 1 1 1 1 MYND finger YajC PF02699.10 CEP13375.1 - 0.064 12.9 1.9 0.26 11.0 0.2 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit DUF581 PF04570.9 CEP13375.1 - 0.25 10.6 6.5 0.58 9.4 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF581) zf-Mss51 PF13824.1 CEP13375.1 - 0.36 10.7 5.6 0.81 9.5 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 MAD PF05557.8 CEP13376.1 - 1.8e-17 62.7 72.8 2e-13 49.3 38.0 3.8 1 1 1 2 2 2 2 Mitotic checkpoint protein Acetyltransf_1 PF00583.19 CEP13377.1 - 3.3e-13 49.4 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP13377.1 - 7.1e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GATA PF00320.22 CEP13378.1 - 7.4e-17 60.4 2.8 7.4e-17 60.4 1.9 1.8 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.5 CEP13378.1 - 1.9e-14 52.9 1.4 4.3e-14 51.7 1.0 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DDE_Tnp_1_7 PF13843.1 CEP13379.1 - 1e-07 31.3 0.0 1.2e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 RhoGAP PF00620.22 CEP13381.1 - 6.6e-27 93.9 0.0 2.2e-26 92.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.12 CEP13381.1 - 1.1e-24 86.5 0.1 2.8e-24 85.2 0.1 1.8 1 0 0 1 1 1 1 MyTH4 domain Pkinase PF00069.20 CEP13382.1 - 6.6e-68 228.6 0.0 8.8e-68 228.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13382.1 - 5e-32 110.9 0.0 7e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP13382.1 - 7.5e-10 38.2 0.0 3.7e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_C PF00433.19 CEP13382.1 - 0.0031 18.0 0.7 0.0057 17.1 0.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain E1-E2_ATPase PF00122.15 CEP13383.1 - 4.2e-63 212.4 9.1 4.2e-63 212.4 6.3 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP13383.1 - 2.7e-35 121.5 8.1 2.7e-35 121.5 5.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP13383.1 - 3e-35 122.5 0.2 4.7e-34 118.6 0.1 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP13383.1 - 1.7e-19 69.5 0.0 4.1e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CEP13383.1 - 6e-16 57.6 0.0 1.8e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEP13383.1 - 2.8e-14 53.7 0.0 1.3e-13 51.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP13383.1 - 7.4e-08 32.2 0.7 2.8e-05 23.8 0.2 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1622 PF07784.6 CEP13383.1 - 0.02 14.5 0.6 0.061 12.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) PAS_3 PF08447.6 CEP13384.1 - 2.7e-13 49.8 0.0 3.5e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 CEP13384.1 - 1.9e-08 34.5 0.0 0.0087 16.4 0.0 2.6 2 1 1 3 3 3 2 PAS domain PAS_11 PF14598.1 CEP13384.1 - 5.1e-07 29.6 0.1 9.4e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 CEP13384.1 - 9.7e-07 28.5 0.0 0.0039 16.9 0.0 2.2 2 0 0 2 2 2 2 PAS fold DUF128 PF01995.11 CEP13384.1 - 0.0026 16.7 0.0 0.0065 15.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF128 Glyco_trans_1_2 PF13524.1 CEP13384.1 - 0.041 14.1 0.0 0.27 11.5 0.0 2.2 3 0 0 3 3 3 0 Glycosyl transferases group 1 Sulfotransfer_3 PF13469.1 CEP13384.1 - 0.17 12.8 0.0 0.24 12.3 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family SpoU_methylase PF00588.14 CEP13385.1 - 1e-26 93.4 0.0 1.4e-25 89.7 0.0 2.8 3 0 0 3 3 3 1 SpoU rRNA Methylase family XPG_I PF00867.13 CEP13386.1 - 4.3e-21 74.7 0.0 8.9e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CEP13386.1 - 1.5e-10 41.1 0.0 5.4e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CEP13386.1 - 0.023 14.2 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing DUF2670 PF10875.3 CEP13386.1 - 0.12 12.4 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) zf-C2H2 PF00096.21 CEP13387.1 - 5.2e-21 73.6 59.5 2e-05 24.6 2.2 8.5 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP13387.1 - 6.8e-19 66.7 52.0 0.0019 18.3 0.1 8.6 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP13387.1 - 1.2e-09 37.7 18.7 0.00027 20.7 0.4 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 CEP13387.1 - 3.7e-07 30.1 31.6 0.0071 16.5 0.3 7.0 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP13387.1 - 5.2e-06 26.4 33.1 0.0027 17.7 0.2 7.0 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CEP13387.1 - 2.2e-05 24.5 60.7 0.016 15.4 0.3 9.2 9 1 0 9 9 9 5 Zinc-finger double domain GAGA PF09237.6 CEP13387.1 - 0.00078 18.9 6.9 0.002 17.6 1.4 3.3 2 1 1 3 3 3 1 GAGA factor zf-Di19 PF05605.7 CEP13387.1 - 0.0098 15.9 3.5 0.0098 15.9 2.4 6.1 3 1 4 7 7 6 4 Drought induced 19 protein (Di19), zinc-binding Arc_trans_TRASH PF08394.5 CEP13387.1 - 0.028 14.5 3.6 0.52 10.5 0.2 3.6 2 1 0 2 2 2 0 Archaeal TRASH domain zf-C2H2_2 PF12756.2 CEP13387.1 - 0.42 10.7 33.1 1.7 8.7 0.4 6.1 1 1 4 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-HYPF PF07503.7 CEP13387.1 - 0.57 9.6 6.3 11 5.5 1.2 3.7 3 0 0 3 3 3 0 HypF finger RVT_1 PF00078.22 CEP13389.1 - 2.6e-06 26.9 0.0 4.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S21 PF00716.12 CEP13390.1 - 0.029 13.7 3.9 0.053 12.8 2.7 1.5 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DUF4297 PF14130.1 CEP13390.1 - 0.064 13.1 2.6 4.2 7.2 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4297) TFIIA PF03153.8 CEP13390.1 - 0.24 11.2 7.8 0.36 10.6 5.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR_HSR1 PF01926.18 CEP13391.1 - 2.4e-09 37.1 0.0 1.5e-08 34.6 0.0 2.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP13391.1 - 9.5e-06 25.1 0.0 0.00085 18.7 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEP13391.1 - 0.0012 18.0 0.1 0.0074 15.4 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CEP13391.1 - 0.0015 19.0 0.2 0.016 15.6 0.0 2.5 3 0 0 3 3 3 1 Miro-like protein FeoB_N PF02421.13 CEP13391.1 - 0.01 15.0 0.0 0.88 8.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.17 CEP13391.1 - 0.024 14.0 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Ras family AIG1 PF04548.11 CEP13391.1 - 0.17 10.9 0.8 3.5 6.6 0.1 2.3 1 1 0 2 2 2 0 AIG1 family Dynamin_N PF00350.18 CEP13391.1 - 2 8.2 4.9 7.1 6.4 1.1 2.9 2 1 0 2 2 2 0 Dynamin family DUF747 PF05346.6 CEP13392.1 - 8.1e-104 347.2 13.0 1.4e-103 346.4 9.0 1.4 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF1308 PF07000.6 CEP13394.1 - 1.8e-46 158.4 0.0 2.4e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) REGB_T4 PF10715.4 CEP13394.1 - 0.0021 18.2 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease RegB T4-bacteriophage encoded DUF1115 PF06544.7 CEP13394.1 - 0.043 13.4 0.0 0.6 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) F_bP_aldolase PF01116.15 CEP13395.1 - 3.1e-97 325.1 0.0 4.4e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.12 CEP13395.1 - 0.14 11.4 0.6 1.6 7.9 0.1 2.1 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Strabismus PF06638.6 CEP13395.1 - 0.4 8.9 1.1 12 4.0 0.6 2.1 2 0 0 2 2 2 0 Strabismus protein LSM PF01423.17 CEP13396.1 - 2.4e-17 62.2 0.1 2.7e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEP13396.1 - 4.1e-05 23.4 0.1 4.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Pox_Ag35 PF03286.9 CEP13397.1 - 0.028 13.9 1.8 0.031 13.8 1.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 CEP13397.1 - 0.043 12.3 2.3 0.047 12.1 1.6 1.1 1 0 0 1 1 1 0 Daxx Family Prothymosin PF03247.9 CEP13397.1 - 0.075 13.1 11.7 0.15 12.2 8.1 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family TFIIF_alpha PF05793.7 CEP13397.1 - 0.3 9.3 12.2 0.43 8.8 8.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 CEP13397.1 - 0.76 7.7 3.5 0.79 7.6 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CEP13397.1 - 1.3 6.8 8.7 1.5 6.6 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 CEP13397.1 - 6.8 5.8 8.7 9.3 5.3 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein GRASP55_65 PF04495.9 CEP13398.1 - 1e-07 32.0 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CEP13398.1 - 4e-07 29.8 0.0 7.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CEP13398.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DegS PF05384.6 CEP13398.1 - 0.0021 17.2 0.7 1.6 7.9 0.1 2.2 2 0 0 2 2 2 2 Sensor protein DegS Pox_A6 PF04924.7 CEP13398.1 - 0.0033 16.2 0.1 0.0053 15.6 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A6 protein Prefoldin_2 PF01920.15 CEP13398.1 - 0.04 13.6 1.4 0.75 9.5 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF948 PF06103.6 CEP13398.1 - 0.041 13.7 1.6 3.8 7.4 0.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SRP54_N PF02881.14 CEP13398.1 - 0.053 13.6 0.5 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Hemerythrin PF01814.18 CEP13398.1 - 0.095 12.8 1.3 0.48 10.5 0.1 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Enkurin PF13864.1 CEP13398.1 - 0.13 12.4 1.0 0.42 10.8 0.1 2.1 2 0 0 2 2 2 0 Calmodulin-binding ALIX_LYPXL_bnd PF13949.1 CEP13398.1 - 0.18 10.7 1.0 0.38 9.6 0.6 1.5 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV HALZ PF02183.13 CEP13398.1 - 0.25 11.0 3.0 0.16 11.7 0.3 2.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 CEP13400.1 - 0.0014 18.5 4.8 0.0021 17.8 3.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 CEP13400.1 - 0.048 13.4 2.4 0.11 12.3 1.6 1.5 1 0 0 1 1 1 0 Laminin Domain II OrfB_Zn_ribbon PF07282.6 CEP13400.1 - 0.12 12.0 4.3 1.8 8.2 3.0 2.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2_jaz PF12171.3 CEP13401.1 - 0.0017 18.4 0.7 0.004 17.2 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP13401.1 - 0.0038 17.3 0.3 0.0067 16.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CEP13401.1 - 0.04 14.0 1.8 0.04 14.0 1.2 2.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Cu-oxidase_2 PF07731.9 CEP13402.1 - 2.5e-40 137.1 9.0 4.1e-38 130.0 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CEP13402.1 - 5.2e-36 122.9 7.5 5.2e-33 113.2 0.3 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 CEP13402.1 - 2.1e-31 108.9 3.8 4.6e-31 107.8 0.2 2.7 3 0 0 3 3 3 1 Multicopper oxidase UQ_con PF00179.21 CEP13403.1 - 3.2e-44 149.7 0.0 3.6e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.6 CEP13403.1 - 0.0085 15.5 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 CEP13403.1 - 0.0094 15.8 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain CTP_transf_2 PF01467.21 CEP13404.1 - 4.8e-12 46.2 0.1 1.3e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase Sulfotransfer_1 PF00685.22 CEP13405.1 - 2.7e-09 36.6 0.1 8.8e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase domain DUF3270 PF11674.3 CEP13406.1 - 0.33 10.9 2.5 0.83 9.7 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) p450 PF00067.17 CEP13407.1 - 3.9e-70 236.6 0.1 5.1e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CP2 PF04516.10 CEP13408.1 - 1.5e-54 184.5 0.7 4.2e-54 183.1 0.5 1.8 1 0 0 1 1 1 1 CP2 transcription factor Amidohydro_1 PF01979.15 CEP13409.1 - 4.3e-58 197.5 5.2 7.1e-58 196.8 3.6 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 CEP13409.1 - 1.6e-54 183.2 1.3 2.8e-54 182.3 0.9 1.4 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Abhydrolase_3 PF07859.8 CEP13409.1 - 1e-42 146.0 0.1 3.1e-42 144.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Urease_beta PF00699.15 CEP13409.1 - 7.8e-42 141.1 0.0 1.7e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 CEP13409.1 - 2.3e-33 114.1 0.0 7.3e-33 112.5 0.0 1.9 2 0 0 2 2 2 1 Urease, gamma subunit DUF2424 PF10340.4 CEP13409.1 - 3.3e-16 58.9 0.1 7.2e-16 57.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Amidohydro_3 PF07969.6 CEP13409.1 - 0.00013 21.3 0.3 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 CEP13409.1 - 0.00068 19.4 1.2 0.0023 17.7 0.8 1.9 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_5 PF12695.2 CEP13409.1 - 0.0038 17.0 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CEP13409.1 - 0.18 10.4 0.7 0.82 8.3 0.5 1.8 1 1 0 1 1 1 0 Carboxylesterase family Isochorismatase PF00857.15 CEP13410.1 - 5.1e-11 42.8 0.0 7.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Phage-tail_3 PF13550.1 CEP13411.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative phage tail protein RVT_1 PF00078.22 CEP13412.1 - 1.8e-07 30.7 0.0 2.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nrap PF03813.9 CEP13415.1 - 0.0086 13.6 0.0 0.0091 13.5 0.0 1.0 1 0 0 1 1 1 1 Nrap protein adh_short PF00106.20 CEP13417.1 - 5.9e-24 84.8 0.1 7.7e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP13417.1 - 2.4e-12 47.1 0.0 3.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP13417.1 - 2.4e-07 30.5 0.0 3.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEP13417.1 - 1e-05 25.6 0.1 1.3e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CEP13417.1 - 4.5e-05 23.0 0.1 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CEP13417.1 - 0.018 14.0 0.1 0.033 13.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 CEP13417.1 - 0.041 13.1 0.1 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family GidB PF02527.10 CEP13417.1 - 0.097 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G 3HCDH_N PF02737.13 CEP13417.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 CEP13418.1 - 4.4e-56 189.9 0.5 9e-56 188.8 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13418.1 - 1.8e-40 138.6 0.2 2.8e-40 138.0 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MerR_2 PF13591.1 CEP13418.1 - 0.0044 16.5 0.6 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 MerR HTH family regulatory protein APH PF01636.18 CEP13418.1 - 0.0069 16.1 0.1 4.3 6.9 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family OSR1_C PF12202.3 CEP13418.1 - 0.078 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C terminal ADIP PF11559.3 CEP13418.1 - 0.43 10.4 12.8 0.077 12.8 5.7 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding RNB PF00773.14 CEP13420.1 - 2.3e-87 293.3 0.0 2.3e-87 293.3 0.0 2.8 3 0 0 3 3 3 1 RNB domain OB_RNB PF08206.6 CEP13420.1 - 0.00051 19.4 0.0 0.0015 17.9 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain Glyco_trans_2_3 PF13632.1 CEP13421.1 - 1e-13 51.4 0.8 1e-13 51.4 0.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DDE_Tnp_IS66_C PF13817.1 CEP13421.1 - 0.024 14.6 0.1 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 IS66 C-terminal element PI-PLC-X PF00388.14 CEP13421.1 - 0.03 13.7 0.3 0.14 11.5 0.0 1.9 1 1 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain RIO1 PF01163.17 CEP13422.1 - 1e-74 250.0 2.2 1e-74 250.0 1.5 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CEP13422.1 - 0.00053 19.8 0.1 0.94 9.1 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEP13422.1 - 0.0046 16.0 0.3 0.026 13.5 0.2 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.9 CEP13422.1 - 0.15 10.0 18.6 0.26 9.2 12.9 1.4 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 CEP13422.1 - 0.36 10.3 28.7 0.053 13.1 11.5 2.5 2 0 0 2 2 2 0 YL1 nuclear protein RR_TM4-6 PF06459.7 CEP13422.1 - 7.1 6.4 13.2 18 5.1 9.2 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CEP13422.1 - 7.6 6.2 10.0 6.8 6.4 3.2 2.3 2 0 0 2 2 2 0 DDHD domain HSP90 PF00183.13 CEP13423.1 - 2.4e-144 481.6 11.1 3.2e-144 481.2 7.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CEP13423.1 - 6.4e-12 45.3 0.1 2.2e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CEP13423.1 - 4.6e-09 35.9 0.0 9.2e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M50B PF13398.1 CEP13424.1 - 8.6e-54 181.9 17.4 8.6e-54 181.9 12.0 1.4 1 1 1 2 2 2 1 Peptidase M50B-like Erg28 PF03694.8 CEP13424.1 - 0.012 15.6 1.8 0.015 15.3 0.2 1.9 2 0 0 2 2 2 0 Erg28 like protein DUF373 PF04123.8 CEP13424.1 - 1.2 8.1 8.8 1.5 7.7 3.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF373) DUF2678 PF10856.3 CEP13424.1 - 4 7.2 7.5 1.3 8.8 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2678) POM121 PF15229.1 CEP13425.1 - 0.028 13.8 2.3 0.032 13.6 1.6 1.0 1 0 0 1 1 1 0 POM121 family AT_hook PF02178.14 CEP13425.1 - 0.095 12.4 2.6 0.19 11.5 1.8 1.5 1 0 0 1 1 1 0 AT hook motif APG6 PF04111.7 CEP13426.1 - 0.05 12.6 2.3 0.062 12.3 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF879 PF05947.7 CEP13426.1 - 0.058 11.7 0.3 0.068 11.5 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) APG6 PF04111.7 CEP13427.1 - 0.052 12.5 1.7 0.059 12.4 1.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 RVT_1 PF00078.22 CEP13428.1 - 3.2e-17 62.6 0.0 4.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Apt1 PF10351.4 CEP13428.1 - 0.062 12.1 0.8 0.087 11.6 0.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tenui_NCP PF04876.7 CEP13428.1 - 0.11 12.0 0.1 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein Asp_protease_2 PF13650.1 CEP13430.1 - 0.00018 21.9 0.0 0.00038 20.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP13430.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Herpes_UL31 PF02718.9 CEP13430.1 - 0.044 12.4 0.4 0.065 11.9 0.0 1.4 2 0 0 2 2 2 0 Herpesvirus UL31-like protein zf-CCHC PF00098.18 CEP13430.1 - 0.11 12.4 2.6 0.25 11.3 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle CAP PF00188.21 CEP13432.1 - 0.051 14.0 0.2 0.073 13.5 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Peptidase_C93 PF06035.6 CEP13437.1 - 0.051 12.9 0.2 0.15 11.5 0.1 1.8 1 1 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Nup_retrotrp_bd PF10599.4 CEP13438.1 - 0.17 12.5 4.6 0.26 11.9 3.2 1.5 1 1 0 1 1 1 0 Retro-transposon transporting motif YL1 PF05764.8 CEP13440.1 - 0.00077 19.1 4.8 0.00077 19.1 3.4 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Transferase PF02458.10 CEP13441.1 - 1.1e-29 103.1 0.0 4.2e-29 101.2 0.0 1.7 1 1 0 1 1 1 1 Transferase family Rrp15p PF07890.7 CEP13442.1 - 1.2e-33 115.9 8.9 1.2e-33 115.9 6.2 2.5 2 1 0 2 2 2 1 Rrp15p Daxx PF03344.10 CEP13442.1 - 0.00042 18.9 24.0 0.00045 18.8 16.6 1.1 1 0 0 1 1 1 1 Daxx Family BSP_II PF05432.6 CEP13442.1 - 0.021 14.1 16.0 0.032 13.5 11.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TPT PF03151.11 CEP13443.1 - 8.1e-29 100.2 15.8 8.1e-29 100.2 11.0 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CEP13443.1 - 3.2e-10 40.1 34.2 1.3e-07 31.6 7.1 2.7 2 2 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CEP13443.1 - 0.00096 19.3 5.2 0.00096 19.3 3.6 3.7 2 2 2 4 4 4 1 Multidrug resistance efflux transporter UAA PF08449.6 CEP13443.1 - 0.0057 15.6 28.6 0.019 13.8 19.8 1.9 1 1 0 1 1 1 1 UAA transporter family LcrR PF09621.5 CEP13443.1 - 0.027 13.7 0.1 0.078 12.2 0.0 1.7 1 1 0 1 1 1 0 Type III secretion system regulator (LcrR) PgaD PF13994.1 CEP13443.1 - 0.18 11.2 6.2 0.7 9.3 0.3 2.9 3 0 0 3 3 3 0 PgaD-like protein GWT1 PF06423.7 CEP13443.1 - 4.8 7.2 12.3 0.16 12.0 3.2 2.4 2 1 1 3 3 3 0 GWT1 G-patch PF01585.18 CEP13444.1 - 3.2e-15 55.6 1.4 5.8e-15 54.7 1.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CEP13444.1 - 2e-07 30.7 0.1 2e-07 30.7 0.1 3.0 4 0 0 4 4 4 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 CEP13444.1 - 0.0053 16.8 0.5 0.01 15.9 0.4 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CEP13444.1 - 0.015 15.5 0.2 0.039 14.3 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Trypan_PARP PF05887.6 CEP13444.1 - 0.02 14.7 1.9 0.02 14.7 1.3 2.1 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) zf-C2H2_4 PF13894.1 CEP13444.1 - 0.022 15.0 0.1 0.06 13.7 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 CEP13444.1 - 0.05 13.8 0.1 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type MDFI PF15316.1 CEP13444.1 - 1.7 8.5 7.2 6.1 6.7 0.3 2.5 2 0 0 2 2 2 0 MyoD family inhibitor DDE_3 PF13358.1 CEP13445.1 - 4.4e-27 94.6 0.0 6.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP13445.1 - 0.00028 20.4 0.0 0.00062 19.3 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DDE_1 PF03184.14 CEP13445.1 - 0.00057 19.0 0.1 0.0018 17.4 0.1 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_IclR PF09339.5 CEP13445.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_29 PF13551.1 CEP13445.1 - 0.0043 17.1 0.0 0.0085 16.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP13445.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.2 CEP13445.1 - 0.015 15.5 0.0 0.079 13.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.1 CEP13445.1 - 0.069 13.9 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HSP70 PF00012.15 CEP13446.1 - 3.6e-08 31.8 0.0 4.3e-07 28.2 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CEP13446.1 - 0.012 14.2 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.20 CEP13447.1 - 1.1e-63 214.8 0.0 2e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13447.1 - 3.4e-35 121.3 0.0 6.2e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CEP13447.1 - 5.7e-14 51.2 0.0 1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 CEP13447.1 - 2e-05 23.7 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP13447.1 - 0.00011 22.0 0.0 0.11 12.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP13447.1 - 0.00067 18.7 0.0 0.0015 17.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 CEP13447.1 - 0.016 14.4 0.2 0.031 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 CEP13447.1 - 0.027 13.8 0.0 0.078 12.3 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PCI PF01399.22 CEP13448.1 - 1.2e-06 28.7 0.4 6e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 PCI domain Histone PF00125.19 CEP13449.1 - 2e-15 56.6 0.2 2.5e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEP13449.1 - 2.7e-05 24.2 0.1 3.7e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CEP13449.1 - 5.4e-05 23.0 0.1 7.6e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CEP13449.1 - 0.00021 21.3 0.1 0.00038 20.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CEP13449.1 - 0.0098 15.1 0.0 0.0098 15.1 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CEP13449.1 - 0.052 13.2 0.1 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 CEP13449.1 - 0.13 12.5 0.1 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CEP13450.1 - 1.4e-31 108.4 0.4 2.1e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEP13450.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CEP13450.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CEP13450.1 - 0.014 14.6 1.1 0.023 13.9 0.8 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CEP13450.1 - 0.019 14.6 0.1 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Fungal_trans PF04082.13 CEP13451.1 - 3e-18 65.6 6.3 5.9e-18 64.6 3.9 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP13451.1 - 1.1e-09 37.9 12.4 1.9e-09 37.2 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SARS_3b PF12383.3 CEP13452.1 - 0.018 14.9 0.5 0.022 14.7 0.3 1.1 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein DHBP_synthase PF00926.14 CEP13455.1 - 1.2e-77 259.5 0.1 1.4e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Flavokinase PF01687.12 CEP13456.1 - 8.2e-42 142.0 0.0 1e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Syntaxin_2 PF14523.1 CEP13457.1 - 0.016 15.2 5.6 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Syntaxin-like protein LigT_PEase PF02834.11 CEP13457.1 - 0.023 14.6 0.1 3.1 7.8 0.0 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF3322 PF11795.3 CEP13457.1 - 0.026 14.1 1.5 0.19 11.3 0.2 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) STOP PF05217.7 CEP13457.1 - 0.32 10.6 4.5 0.071 12.8 0.3 1.8 2 0 0 2 2 2 0 STOP protein Endotoxin_N PF03945.9 CEP13457.1 - 0.5 9.7 5.3 0.24 10.7 2.0 1.7 2 1 0 2 2 2 0 delta endotoxin, N-terminal domain ATP-synt_ab_N PF02874.18 CEP13459.1 - 1.2e-24 86.2 1.8 2.3e-24 85.4 1.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.20 CEP13459.1 - 0.0011 18.4 0.2 0.0025 17.3 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF1227 PF06777.6 CEP13460.1 - 5.2e-60 201.3 0.2 9.7e-60 200.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CEP13460.1 - 4.6e-51 172.6 0.1 8.2e-51 171.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CEP13460.1 - 5.4e-44 150.0 0.0 1.1e-43 149.1 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 CEP13460.1 - 0.0038 16.0 0.0 1.2 7.8 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 CEP13460.1 - 0.036 13.2 0.0 0.6 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 CEP13460.1 - 0.048 12.6 0.0 0.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Inositol_P PF00459.20 CEP13461.1 - 2.4e-60 204.1 0.4 3.1e-60 203.7 0.3 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family ADH_N PF08240.7 CEP13462.1 - 3.4e-29 100.7 2.0 5.3e-29 100.1 1.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP13462.1 - 2.5e-24 85.2 0.0 4e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Isochorismatase PF00857.15 CEP13464.1 - 9.3e-10 38.7 0.1 1.4e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DDE_3 PF13358.1 CEP13465.1 - 2.2e-06 27.4 0.0 8.2e-06 25.6 0.0 1.9 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.1 CEP13465.1 - 0.085 12.2 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding SNARE_assoc PF09335.6 CEP13466.1 - 1.7e-21 76.7 4.3 3.9e-20 72.2 3.7 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein PCI_Csn8 PF10075.4 CEP13467.1 - 2e-31 108.7 0.6 3.9e-31 107.7 0.4 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CEP13467.1 - 5.5e-30 104.4 0.5 7.9e-30 103.9 0.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Cornichon PF03311.9 CEP13468.1 - 4e-49 165.9 10.3 4.5e-49 165.8 7.1 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 CEP13468.1 - 0.086 12.3 8.6 0.17 11.3 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) O-FucT PF10250.4 CEP13469.1 - 2.5e-08 33.4 0.0 0.00024 20.3 0.0 2.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Casc1 PF12366.3 CEP13469.1 - 0.059 12.8 0.5 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 CBS PF00571.23 CEP13470.1 - 1.8e-16 59.6 0.6 1.5e-05 24.6 0.0 3.5 4 0 0 4 4 4 3 CBS domain ALS_ss_C PF10369.4 CEP13471.1 - 7.9e-20 70.3 0.1 2.7e-17 62.2 0.0 2.6 3 0 0 3 3 3 2 Small subunit of acetolactate synthase ACT PF01842.20 CEP13471.1 - 9.6e-13 47.3 0.2 2.1e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 CEP13471.1 - 4e-10 39.3 0.1 7.7e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 CEP13471.1 - 0.1 12.9 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 ACT domain ResIII PF04851.10 CEP13472.1 - 1.4e-28 99.9 0.1 1.4e-28 99.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEP13472.1 - 2.6e-12 46.4 0.0 7.1e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP13472.1 - 7.4e-10 38.5 0.1 2.3e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 CEP13472.1 - 0.0013 17.7 0.0 0.0013 17.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_C_2 PF13307.1 CEP13472.1 - 0.015 15.2 0.2 0.13 12.1 0.0 2.5 3 0 0 3 3 3 0 Helicase C-terminal domain T2SE PF00437.15 CEP13472.1 - 0.027 13.3 0.3 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF4410 PF14366.1 CEP13472.1 - 0.39 10.4 4.3 0.28 10.9 1.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4410) AAA_11 PF13086.1 CEP13472.1 - 1 8.8 7.6 2.6 7.5 0.1 3.1 2 1 1 3 3 3 0 AAA domain GST_N_2 PF13409.1 CEP13473.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP13473.1 - 0.0032 17.6 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CEP13473.1 - 0.025 14.7 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CEP13474.1 - 4.4e-06 27.1 0.0 8.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP13474.1 - 1.3e-05 25.0 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CEP13474.1 - 0.0069 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEP13474.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP13475.1 - 4.6e-06 27.0 0.0 8.3e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP13475.1 - 1.2e-05 25.2 0.3 2.2e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CEP13475.1 - 0.00018 21.5 0.0 0.00044 20.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CEP13475.1 - 0.0067 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP13475.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEP13475.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LIM PF00412.17 CEP13476.1 - 5.2e-15 55.2 17.9 6e-12 45.4 6.3 2.2 2 0 0 2 2 2 2 LIM domain Churchill PF06573.6 CEP13476.1 - 0.072 13.0 0.4 0.072 13.0 0.3 1.9 2 0 0 2 2 2 0 Churchill protein DUF605 PF04652.11 CEP13476.1 - 1.4 8.2 5.7 1.8 7.8 3.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF2616 PF11077.3 CEP13476.1 - 4.1 6.8 6.9 0.7 9.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) CsbD PF05532.7 CEP13477.1 - 4.1e-14 51.9 19.4 3.4e-10 39.4 4.8 2.1 1 1 1 2 2 2 2 CsbD-like DUF883 PF05957.8 CEP13477.1 - 0.64 10.4 5.1 0.48 10.8 2.0 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mito_carr PF00153.22 CEP13478.1 - 6e-65 214.9 8.4 1.9e-21 75.5 0.0 3.9 3 0 0 3 3 3 3 Mitochondrial carrier protein FUSC_2 PF13515.1 CEP13478.1 - 7.5e-18 64.6 13.2 7.5e-18 64.6 9.1 3.1 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 CEP13478.1 - 6.9e-15 54.6 16.1 5.7e-12 45.0 1.6 2.9 2 1 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 CEP13478.1 - 2.7e-12 45.9 0.9 2.7e-12 45.9 0.6 3.0 2 1 0 3 3 3 2 Fusaric acid resistance protein family DUF2422 PF10337.4 CEP13478.1 - 1.5e-11 43.7 12.5 1.5e-11 43.7 8.6 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CEP13478.1 - 2e-10 40.6 1.9 2e-10 40.6 1.3 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) EF-hand_7 PF13499.1 CEP13478.1 - 1.7e-07 31.2 1.2 0.00023 21.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP13478.1 - 9.8e-05 21.9 1.4 5.1 7.2 0.0 4.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 CEP13478.1 - 0.00053 19.5 0.3 0.15 11.6 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 CEP13478.1 - 0.0032 16.6 0.4 0.59 9.5 0.0 3.8 4 0 0 4 4 4 1 EF hand Vps5 PF09325.5 CEP13479.1 - 0.062 12.5 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Vps5 C terminal like PaaSYMP PF14738.1 CEP13479.1 - 0.079 12.6 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 FAM110_C PF14160.1 CEP13479.1 - 0.082 13.8 0.6 0.15 13.0 0.1 1.6 2 0 0 2 2 2 0 Centrosome-associated C terminus rve PF00665.21 CEP13480.1 - 3.2e-18 65.9 0.0 9.8e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CEP13480.1 - 0.0017 17.8 0.0 0.0056 16.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain NOPS PF08075.6 CEP13480.1 - 0.13 12.6 0.4 30 5.1 0.1 3.0 3 0 0 3 3 3 0 NOPS (NUC059) domain RVT_1 PF00078.22 CEP13482.1 - 2.1e-10 40.3 0.0 0.00033 20.0 0.0 2.7 1 1 2 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CEP13482.1 - 3.7e-06 26.5 8.3 6.7e-06 25.7 5.8 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 CEP13482.1 - 0.05 13.5 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 CEP13482.1 - 0.16 11.6 5.2 0.45 10.2 3.6 1.7 1 0 0 1 1 1 0 Zinc knuckle ETC_C1_NDUFA4 PF04800.7 CEP13484.1 - 7e-34 115.7 0.5 9.4e-34 115.3 0.4 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF3892 PF13031.1 CEP13484.1 - 0.045 14.1 0.1 0.096 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) Lon_C PF05362.8 CEP13485.1 - 2.6e-70 235.8 0.0 4.9e-70 235.0 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CEP13485.1 - 8.4e-25 87.4 0.0 2.1e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CEP13485.1 - 1.8e-20 73.5 0.1 2.3e-19 69.9 0.0 2.6 3 0 0 3 3 3 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 CEP13485.1 - 1.2e-08 34.5 0.0 3.8e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 CEP13485.1 - 5.1e-07 29.5 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP13485.1 - 1.3e-06 28.4 0.4 5.4e-06 26.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CEP13485.1 - 3.9e-06 26.7 0.0 4.1e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.9 CEP13485.1 - 1.3e-05 25.1 0.0 4.7e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.6 CEP13485.1 - 1.4e-05 24.0 0.0 2.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 CEP13485.1 - 4.9e-05 24.1 0.1 0.00049 20.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CEP13485.1 - 5.4e-05 22.8 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP13485.1 - 7.5e-05 22.8 0.0 0.0051 16.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEP13485.1 - 0.00017 20.7 0.0 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CEP13485.1 - 0.00072 19.0 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CEP13485.1 - 0.0038 17.5 0.2 0.01 16.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 CEP13485.1 - 0.0065 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CEP13485.1 - 0.013 14.5 0.1 0.041 12.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 CEP13485.1 - 0.017 15.4 1.7 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CEP13485.1 - 0.021 15.0 0.0 0.072 13.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CEP13485.1 - 0.024 14.2 0.3 0.34 10.5 0.0 3.0 3 0 0 3 3 3 0 NACHT domain SKI PF01202.17 CEP13485.1 - 0.027 14.3 0.5 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Arch_ATPase PF01637.13 CEP13485.1 - 0.029 14.0 0.1 3.8 7.1 0.0 3.1 3 0 0 3 3 3 0 Archaeal ATPase TIP49 PF06068.8 CEP13485.1 - 0.039 12.6 0.2 2.2 6.9 0.0 2.4 3 0 0 3 3 3 0 TIP49 C-terminus DUF815 PF05673.8 CEP13485.1 - 0.057 12.3 0.0 0.98 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CEP13485.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.4 CEP13485.1 - 0.093 12.6 0.7 0.41 10.5 0.0 2.5 2 0 0 2 2 1 0 C-terminal, D2-small domain, of ClpB protein AAA_25 PF13481.1 CEP13485.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEP13485.1 - 0.26 11.5 2.1 1.2 9.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Ran-binding PF05508.6 CEP13486.1 - 7.3e-37 126.8 2.6 1.8e-34 119.0 1.8 3.0 1 1 0 1 1 1 1 RanGTP-binding protein Alpha-amylase_C PF02806.13 CEP13487.1 - 1.2e-25 89.4 0.1 3.1e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CEP13487.1 - 4.2e-16 59.2 0.0 2.5e-11 43.5 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 CEP13487.1 - 3.8e-13 49.2 0.1 9e-13 48.0 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) FAR1 PF03101.10 CEP13490.1 - 1.4e-08 35.1 5.2 2.9e-08 34.1 3.6 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF2819 PF10995.3 CEP13490.1 - 0.22 10.2 2.2 0.14 10.9 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2819) MULE PF10551.4 CEP13491.1 - 2.4e-09 37.2 0.1 6.2e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 CEP13491.1 - 1e-07 32.3 4.2 3e-07 30.8 2.9 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain PCI PF01399.22 CEP13491.1 - 0.0025 18.1 3.1 1.6 9.0 0.1 3.5 2 1 1 3 3 3 2 PCI domain DUF2877 PF11392.3 CEP13491.1 - 0.0056 16.8 0.7 4.5 7.5 0.1 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF2877) DUF4110 PF13422.1 CEP13491.1 - 0.01 15.6 1.0 4.9 7.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) RRM_1 PF00076.17 CEP13491.1 - 0.042 13.4 0.0 16 5.2 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HHH_4 PF14490.1 CEP13491.1 - 0.085 12.6 0.5 20 5.0 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix containing domain DUF1661 PF07877.6 CEP13491.1 - 0.98 8.9 4.8 73 2.9 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1661) Cytokin-bind PF09265.5 CEP13492.1 - 0.037 13.1 0.4 0.051 12.7 0.2 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Peptidase_C65 PF10275.4 CEP13492.1 - 0.066 12.5 0.2 0.066 12.5 0.1 1.7 2 0 0 2 2 2 0 Peptidase C65 Otubain Macoilin PF09726.4 CEP13492.1 - 0.094 10.9 2.3 0.11 10.7 1.6 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3488 PF11992.3 CEP13493.1 - 0.031 12.9 1.8 0.028 13.0 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3488) L_HGMIC_fpl PF10242.4 CEP13493.1 - 0.53 10.2 4.9 0.2 11.6 1.2 1.6 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein 7TM_GPCR_Sri PF10327.4 CEP13493.1 - 0.91 8.4 8.7 1.7 7.5 6.0 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri F-box-like PF12937.2 CEP13494.1 - 7.6e-10 38.3 0.0 1.8e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP13494.1 - 4.4e-07 29.4 0.0 1.5e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain DAGAT PF03982.8 CEP13495.1 - 1.9e-101 338.6 0.0 2.3e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Abhydrolase_3 PF07859.8 CEP13496.1 - 2.4e-26 92.6 0.0 5.8e-26 91.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CEP13496.1 - 3.8e-21 75.4 0.2 9.4e-21 74.1 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CEP13496.1 - 4.5e-08 32.9 0.0 6.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CEP13496.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF2974 PF11187.3 CEP13496.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PapD-like PF14874.1 CEP13497.1 - 2.6e-07 30.5 0.6 0.18 11.7 0.0 6.2 6 0 0 6 6 6 2 Flagellar-associated PapD-like Transglut_C PF00927.17 CEP13497.1 - 0.00016 21.6 0.5 0.037 14.0 0.0 4.9 6 0 0 6 6 6 1 Transglutaminase family, C-terminal ig like domain zf-CCHC_4 PF14392.1 CEP13498.1 - 0.00073 19.1 4.8 0.0063 16.1 0.3 2.7 2 0 0 2 2 2 1 Zinc knuckle MGC-24 PF05283.6 CEP13498.1 - 0.014 15.1 13.2 0.02 14.6 9.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) zf-CCHC PF00098.18 CEP13498.1 - 0.061 13.2 0.3 0.061 13.2 0.2 2.4 3 0 0 3 3 3 0 Zinc knuckle Pol_alpha_B_N PF08418.5 CEP13498.1 - 0.11 12.0 6.2 0.15 11.5 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Mu-like_Com PF10122.4 CEP13498.1 - 2.2 7.4 7.6 6.2 5.9 1.6 2.5 1 1 1 2 2 2 0 Mu-like prophage protein Com FYDLN_acid PF09538.5 CEP13498.1 - 5.6 7.6 14.0 0.43 11.1 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-CCHC_3 PF13917.1 CEP13498.1 - 6 6.6 10.8 0.061 13.0 0.8 2.2 1 1 1 2 2 2 0 Zinc knuckle DUF4515 PF14988.1 CEP13500.1 - 0.01 15.5 2.3 0.013 15.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF2096 PF09869.4 CEP13500.1 - 0.034 14.0 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) PIF1 PF05970.9 CEP13504.1 - 4.9e-14 52.0 0.2 6.3e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP13504.1 - 8.1e-06 23.8 0.0 9.2e-06 23.7 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP13504.1 - 0.00029 20.9 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AdoMet_MTase PF07757.8 CEP13505.1 - 6.8e-39 132.4 0.0 1.3e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 CEP13505.1 - 0.00014 21.5 0.3 0.00086 19.0 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP13505.1 - 0.00017 21.3 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP13505.1 - 0.00017 21.1 0.0 0.00052 19.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CEP13505.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CEP13505.1 - 0.0026 18.3 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP13505.1 - 0.032 14.7 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 CEP13505.1 - 0.043 13.2 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 CEP13505.1 - 0.056 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CEP13505.1 - 0.062 13.3 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRP1_N PF06424.7 CEP13505.1 - 0.43 10.8 5.2 0.4 10.9 0.1 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Podoplanin PF05808.6 CEP13506.1 - 0.017 14.7 11.7 0.047 13.2 8.0 1.9 1 1 0 1 1 1 0 Podoplanin Gly-zipper_Omp PF13488.1 CEP13506.1 - 3.4 7.3 14.0 0.068 12.8 2.0 2.5 2 0 0 2 2 2 0 Glycine zipper F-box-like PF12937.2 CEP13507.1 - 4.3e-06 26.3 0.0 9.5e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP13507.1 - 0.00091 18.8 0.0 0.0026 17.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain eIF-5_eIF-2B PF01873.12 CEP13508.1 - 4e-43 146.0 1.8 3.4e-41 139.8 0.2 2.2 2 0 0 2 2 2 2 Domain found in IF2B/IF5 W2 PF02020.13 CEP13508.1 - 2.7e-22 78.5 2.0 2.7e-22 78.5 1.4 2.1 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Pex19 PF04614.7 CEP13508.1 - 4.4 6.8 10.5 0.36 10.4 3.2 2.1 2 1 1 3 3 3 0 Pex19 protein family Sel1 PF08238.7 CEP13509.1 - 1.1e-103 337.4 115.0 2.5e-09 37.4 0.0 29.2 29 0 0 29 29 29 21 Sel1 repeat TPR_6 PF13174.1 CEP13509.1 - 0.00063 20.0 43.9 4.5 7.9 0.0 15.1 17 0 0 17 17 17 5 Tetratricopeptide repeat PadR PF03551.9 CEP13510.1 - 0.15 11.8 0.0 0.62 9.8 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family RRM_5 PF13893.1 CEP13511.1 - 2.4e-13 49.7 0.0 4.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP13511.1 - 3.6e-12 45.7 0.2 1.2e-11 44.0 0.1 1.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP13511.1 - 1.3e-05 25.0 0.0 2.6e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MAT_Alpha1 PF04769.7 CEP13511.1 - 0.041 13.2 0.2 0.091 12.0 0.1 1.6 1 1 0 1 1 1 0 Mating-type protein MAT alpha 1 3Beta_HSD PF01073.14 CEP13512.1 - 5e-70 235.3 0.0 6.2e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CEP13512.1 - 1.4e-34 119.5 0.0 1.7e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CEP13512.1 - 2.7e-16 59.2 0.0 3.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CEP13512.1 - 8.9e-15 54.2 0.0 1e-13 50.7 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 CEP13512.1 - 1.4e-14 54.5 0.0 1.9e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CEP13512.1 - 1.5e-07 30.6 0.0 7.2e-07 28.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 CEP13512.1 - 0.00035 20.3 0.0 0.0038 16.9 0.0 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 CEP13512.1 - 0.0043 16.9 0.0 0.02 14.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase RNA_pol_A_bac PF01000.21 CEP13513.1 - 7.8e-33 112.9 0.0 1.4e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CEP13513.1 - 1.3e-17 62.7 0.0 2.1e-17 61.9 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 CEP13513.1 - 0.065 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF22 Scramblase PF03803.10 CEP13514.1 - 0.043 12.8 0.2 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Scramblase DCP1 PF06058.8 CEP13515.1 - 3.9e-28 97.9 0.1 8.2e-28 96.9 0.1 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family MAT1 PF06391.8 CEP13515.1 - 0.05 13.1 8.1 0.087 12.3 5.6 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 AAA_23 PF13476.1 CEP13515.1 - 0.31 11.3 14.8 0.12 12.6 8.6 1.4 2 0 0 2 2 2 0 AAA domain bZIP_1 PF00170.16 CEP13516.1 - 6.5e-08 32.4 6.3 6.5e-08 32.4 4.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor SH3_9 PF14604.1 CEP13516.1 - 4.9e-06 26.0 0.0 8.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain bZIP_2 PF07716.10 CEP13516.1 - 2.4e-05 24.0 4.9 2.4e-05 24.0 3.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper SH3_1 PF00018.23 CEP13516.1 - 0.0018 17.6 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain BatA PF07584.6 CEP13516.1 - 0.074 13.2 0.0 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal IncA PF04156.9 CEP13516.1 - 0.08 12.5 0.0 0.08 12.5 0.0 3.2 3 1 0 3 3 3 0 IncA protein SH3_2 PF07653.12 CEP13516.1 - 0.09 12.2 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Podoplanin PF05808.6 CEP13516.1 - 0.17 11.4 0.0 0.95 9.0 0.0 2.2 2 0 0 2 2 2 0 Podoplanin Adeno_E3_CR2 PF02439.10 CEP13516.1 - 0.98 9.0 6.7 0.063 12.8 0.7 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Vac7 PF12751.2 CEP13518.1 - 1.9e-09 36.9 7.8 1.4e-07 30.7 0.0 2.8 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 PH PF00169.24 CEP13519.1 - 9.2e-10 38.6 2.1 2.4e-09 37.3 0.4 2.1 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 CEP13519.1 - 0.00034 20.6 0.5 0.52 10.4 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 CEP13519.1 - 0.0008 19.6 4.2 0.0023 18.1 2.1 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 CEP13519.1 - 0.0018 18.4 1.1 0.0054 16.8 0.8 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 CEP13519.1 - 0.049 13.1 0.2 0.15 11.6 0.1 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain G-gamma PF00631.17 CEP13520.1 - 1.4e-17 63.1 0.0 1.5e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 GGL domain GntR PF00392.16 CEP13520.1 - 0.11 11.9 0.2 0.2 11.1 0.1 1.5 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_29 PF13551.1 CEP13521.1 - 0.0005 20.1 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP13521.1 - 0.0053 17.5 0.1 0.054 14.3 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_AsnC-type PF13404.1 CEP13521.1 - 0.0092 15.5 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 CEP13521.1 - 0.03 13.7 1.2 0.069 12.5 0.9 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2887 PF11103.3 CEP13522.1 - 0.092 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) HTH_29 PF13551.1 CEP13523.1 - 0.0005 20.2 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP13523.1 - 0.0053 17.5 0.1 0.054 14.3 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_AsnC-type PF13404.1 CEP13523.1 - 0.0092 15.5 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 CEP13523.1 - 0.03 13.7 1.2 0.069 12.5 0.9 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Serinc PF03348.10 CEP13524.1 - 6.5e-146 486.4 5.5 7.8e-146 486.1 3.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FA_desaturase PF00487.19 CEP13524.1 - 0.39 10.1 13.3 1.4 8.3 6.6 2.9 2 1 1 3 3 3 0 Fatty acid desaturase DUF218 PF02698.12 CEP13525.1 - 0.00024 20.6 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain LON PF02190.11 CEP13526.1 - 1.3e-14 54.4 0.0 5.4e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 CEP13526.1 - 2.6e-10 39.9 27.8 2.7e-06 27.1 7.1 3.3 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CEP13526.1 - 2.1e-06 27.6 24.5 0.0026 17.7 5.4 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP13526.1 - 1.7e-05 24.3 22.3 0.015 14.9 6.8 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP13526.1 - 9.7e-05 21.9 20.2 0.026 14.1 4.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP13526.1 - 0.00023 20.8 27.3 0.02 14.6 5.8 2.8 2 1 1 3 3 3 2 zinc-RING finger domain zf-RING_2 PF13639.1 CEP13526.1 - 0.043 13.6 24.9 0.47 10.3 5.8 2.9 1 1 2 3 3 3 0 Ring finger domain DUF4496 PF14908.1 CEP13526.1 - 0.056 13.3 1.2 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4496) Ribosomal_L50 PF10501.4 CEP13526.1 - 0.1 12.5 0.3 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Ribosomal subunit 39S zf-RING_6 PF14835.1 CEP13526.1 - 0.18 11.6 12.8 2.5 7.9 1.1 2.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DHODB_Fe-S_bind PF10418.4 CEP13526.1 - 8.6 5.9 7.8 6.6 6.3 0.1 2.6 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B MULE PF10551.4 CEP13527.1 - 7.3e-10 38.8 0.2 2.7e-09 37.0 0.2 2.1 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 CEP13527.1 - 7.6e-05 22.0 0.3 0.00015 21.1 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger Transposase_mut PF00872.13 CEP13527.1 - 0.0001 21.0 0.9 0.00022 19.9 0.6 1.6 1 1 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.1 CEP13527.1 - 0.0016 18.4 1.0 1.4 8.9 0.1 3.4 2 1 0 3 3 3 1 DDE domain DDE_Tnp_ISL3 PF01610.12 CEP13527.1 - 0.0019 17.8 0.2 0.0079 15.7 0.0 2.1 2 0 0 2 2 2 1 Transposase FAR1 PF03101.10 CEP13527.1 - 0.002 18.5 0.5 0.0064 16.9 0.4 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain WRKY PF03106.10 CEP13527.1 - 0.005 16.6 0.2 0.013 15.3 0.1 1.8 1 0 0 1 1 1 1 WRKY DNA -binding domain Pkinase PF00069.20 CEP13529.1 - 2.6e-38 131.6 0.0 1.3e-14 53.9 0.0 3.7 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13529.1 - 1.7e-18 66.6 0.0 2.7e-05 23.3 0.0 4.2 4 0 0 4 4 4 3 Protein tyrosine kinase Kelch_6 PF13964.1 CEP13530.1 - 4.8e-19 67.6 0.7 0.0003 20.8 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CEP13530.1 - 9.6e-18 63.1 0.5 1.6e-05 24.4 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CEP13530.1 - 2.8e-17 62.2 0.2 0.00015 21.6 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 CEP13530.1 - 1e-16 60.4 0.5 8.5e-05 22.2 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP13530.1 - 1.8e-15 56.5 14.2 1.4e-06 28.3 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 CEP13530.1 - 6.1e-15 54.4 0.5 0.0004 19.8 0.0 3.9 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 CEP13530.1 - 7.8e-10 38.7 5.1 0.00034 20.5 0.2 3.3 3 0 0 3 3 3 2 BTB/POZ domain Peptidase_S49_N PF08496.5 CEP13530.1 - 2.4 7.9 18.0 1.4 8.6 6.0 2.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DWNN PF08783.6 CEP13530.1 - 3.6 7.5 0.0 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 DWNN domain Med15 PF09606.5 CEP13530.1 - 9.8 4.2 55.4 0.04 12.1 22.2 3.0 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Aa_trans PF01490.13 CEP13531.1 - 4.1e-62 209.9 33.8 4.9e-62 209.7 23.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CEP13531.1 - 3.2e-07 29.2 44.9 4.2e-07 28.8 31.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2367 PF10164.4 CEP13531.1 - 0.24 11.2 6.0 0.046 13.5 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) DUF3278 PF11683.3 CEP13531.1 - 0.73 9.8 8.2 1.1 9.2 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Aa_trans PF01490.13 CEP13532.1 - 5.7e-47 160.1 23.5 6.4e-47 159.9 16.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CEP13532.1 - 7.6e-06 24.7 33.1 3.2e-05 22.6 22.9 1.8 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 CEP13532.1 - 1.8e-05 23.5 7.2 1.8e-05 23.5 5.0 2.8 2 2 0 3 3 3 1 Spore germination protein DUF2367 PF10164.4 CEP13532.1 - 0.51 10.2 5.0 0.26 11.1 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Aa_trans PF01490.13 CEP13533.1 - 2e-59 201.1 33.1 2.3e-59 200.9 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Helitron_like_N PF14214.1 CEP13534.1 - 5.9e-10 39.1 0.0 4.6e-09 36.2 0.0 2.0 1 1 1 2 2 2 1 Helitron helicase-like domain at N-terminus MCM2_N PF12619.3 CEP13535.1 - 1.3 9.0 11.7 1.4 8.8 8.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 UvrD_C_2 PF13538.1 CEP13538.1 - 1.4e-08 34.8 0.0 2e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEP13538.1 - 2.7e-05 22.1 0.0 5.3e-05 21.1 0.0 1.4 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.13 CEP13538.1 - 0.014 14.9 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.1 CEP13538.1 - 0.091 12.1 0.1 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 CEP13544.1 - 2.7e-06 26.5 0.1 3.1e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 CEP13544.1 - 0.00012 21.7 0.1 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CEP13544.1 - 0.00022 20.3 0.1 0.00024 20.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 CEP13544.1 - 0.00091 19.2 0.3 0.0017 18.3 0.1 1.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 CEP13544.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CEP13544.1 - 0.0029 17.0 0.2 0.04 13.4 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 CEP13544.1 - 0.0058 16.7 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CEP13544.1 - 0.012 15.1 2.6 0.058 12.9 0.5 2.1 1 1 2 3 3 3 0 P-loop containing region of AAA domain NACHT PF05729.7 CEP13544.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 CEP13544.1 - 0.025 14.1 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 CEP13544.1 - 0.028 13.3 0.2 0.058 12.3 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 CEP13544.1 - 0.031 13.4 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 CEP13544.1 - 0.044 12.6 0.3 0.083 11.7 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Septin PF00735.13 CEP13544.1 - 0.045 12.7 0.1 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Septin Herpes_Helicase PF02689.9 CEP13544.1 - 0.046 11.4 0.3 0.045 11.4 0.2 1.3 1 1 0 1 1 1 0 Helicase AAA_23 PF13476.1 CEP13544.1 - 0.058 13.7 0.1 0.065 13.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CEP13544.1 - 0.061 12.0 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 CEP13544.1 - 0.064 13.4 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 CEP13544.1 - 0.081 12.8 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.7 CEP13544.1 - 0.11 11.0 0.2 0.12 10.9 0.2 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA PF00004.24 CEP13544.1 - 0.11 12.6 0.1 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.7 CEP13544.1 - 0.14 11.4 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein KaiC PF06745.8 CEP13544.1 - 0.15 11.1 0.1 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.1 CEP13544.1 - 0.15 11.6 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain Tautomerase PF01361.16 CEP13545.1 - 0.0021 17.5 0.0 0.93 9.1 0.0 2.8 2 0 0 2 2 2 2 Tautomerase enzyme Glyco_hydro_16 PF00722.16 CEP13546.1 - 2.5e-35 121.4 1.2 3e-34 117.9 0.3 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DEAD PF00270.24 CEP13546.1 - 3.2e-14 52.7 0.0 5.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase QCR10 PF09796.4 CEP13546.1 - 8.7e-13 47.7 0.0 2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) zf-H2C2_2 PF13465.1 CEP13546.1 - 0.074 13.3 0.5 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-DHHC PF01529.15 CEP13547.1 - 8.1e-05 22.0 0.1 8.1e-05 22.0 0.1 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Senescence_reg PF04520.8 CEP13547.1 - 0.018 15.5 2.3 0.031 14.7 1.6 1.5 1 0 0 1 1 1 0 Senescence regulator TFIIA PF03153.8 CEP13547.1 - 0.13 12.1 11.1 0.15 11.9 7.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Eaf7 PF07904.8 CEP13547.1 - 1.8 8.5 5.0 2.4 8.1 0.0 2.8 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 Helicase_C PF00271.26 CEP13548.1 - 9.2e-27 92.7 0.1 1.7e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP13548.1 - 1.2e-23 83.4 0.0 9.1e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase API5 PF05918.6 CEP13548.1 - 0.032 12.7 0.7 0.048 12.1 0.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1253 PF06862.7 CEP13548.1 - 0.052 11.9 0.0 0.074 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Helitron_like_N PF14214.1 CEP13549.1 - 2.4e-05 24.1 0.3 4e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Transposase_21 PF02992.9 CEP13550.1 - 8.5e-07 28.2 0.1 1.4e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF947 PF06102.7 CEP13551.1 - 0.28 10.9 2.9 0.64 9.8 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF947) zf-CCHC PF00098.18 CEP13554.1 - 0.0027 17.5 0.2 0.0046 16.8 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 CEP13555.1 - 8.5e-09 35.0 0.0 9.3e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIF1 PF05970.9 CEP13558.1 - 3e-11 42.8 0.1 4.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_22 PF13401.1 CEP13558.1 - 8.3e-06 25.9 0.1 2.4e-05 24.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 CEP13558.1 - 1.6e-05 24.5 0.0 3.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CEP13558.1 - 6.2e-05 22.6 0.0 0.0003 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEP13558.1 - 0.0016 18.5 0.0 0.0051 16.9 0.0 1.8 1 1 1 2 2 2 1 RNA helicase KaiC PF06745.8 CEP13558.1 - 0.006 15.7 0.0 0.55 9.2 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA PF00004.24 CEP13558.1 - 0.0077 16.4 0.2 0.023 14.8 0.1 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CEP13558.1 - 0.009 15.0 0.1 0.013 14.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 CEP13558.1 - 0.02 14.7 0.0 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Mg_chelatase PF01078.16 CEP13558.1 - 0.021 14.0 0.2 0.049 12.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CEP13558.1 - 0.04 14.2 0.0 0.44 10.8 0.0 2.4 3 0 0 3 3 3 0 ABC transporter NTPase_1 PF03266.10 CEP13558.1 - 0.046 13.4 0.0 6 6.5 0.0 2.3 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 CEP13558.1 - 0.051 12.4 0.0 0.094 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 CEP13558.1 - 0.058 13.2 0.6 0.54 10.1 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEP13558.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CEP13558.1 - 0.074 12.5 0.4 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family UvrD-helicase PF00580.16 CEP13558.1 - 0.099 11.9 0.1 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain NACHT PF05729.7 CEP13558.1 - 0.13 11.9 0.1 0.78 9.3 0.0 2.0 2 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 CEP13558.1 - 0.2 11.6 0.5 0.29 11.0 0.4 1.7 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.21 CEP13559.1 - 0.08 12.4 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DHHW PF14286.1 CEP13560.1 - 0.068 12.4 3.5 0.095 12.0 2.4 1.1 1 0 0 1 1 1 0 DHHW protein DASH_Dad2 PF08654.5 CEP13560.1 - 0.32 11.0 5.7 0.68 9.9 3.4 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad2 Pex14_N PF04695.8 CEP13560.1 - 1.6 8.7 20.8 0.3 11.1 11.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rrn6 PF10214.4 CEP13560.1 - 3.4 5.6 18.6 4.1 5.3 12.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BAF1_ABF1 PF04684.8 CEP13560.1 - 4.9 5.8 11.8 5.5 5.7 8.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 CEP13560.1 - 8.5 6.0 12.2 9.2 5.9 8.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-CCHC PF00098.18 CEP13562.1 - 2.9e-07 30.1 12.6 0.00014 21.6 1.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP13562.1 - 0.03 13.8 12.7 0.037 13.5 3.7 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEP13562.1 - 0.25 11.0 9.8 1.1 9.0 1.3 2.5 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.1 CEP13563.1 - 5.3e-22 78.1 0.0 9.5e-22 77.3 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP13563.1 - 0.031 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain ALS2CR8 PF15299.1 CEP13564.1 - 0.015 14.9 0.3 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Cas_Csy1 PF09611.5 CEP13564.1 - 0.11 11.4 0.1 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) Med10 PF09748.4 CEP13568.1 - 0.078 12.7 0.1 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex MitMem_reg PF13012.1 CEP13569.1 - 0.025 14.6 0.3 3.6 7.7 0.1 2.6 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function RVT_1 PF00078.22 CEP13570.1 - 1.7e-07 30.8 0.2 4e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_gE PF02480.11 CEP13572.1 - 0.00061 18.1 0.1 0.0009 17.6 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Podoplanin PF05808.6 CEP13572.1 - 2.8 7.4 22.6 17 4.8 15.7 2.0 1 1 0 1 1 1 0 Podoplanin DUF566 PF04484.7 CEP13572.1 - 4.7 6.6 13.1 8.2 5.8 9.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) TM1506 PF08973.5 CEP13573.1 - 0.091 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) DUF2600 PF10776.4 CEP13573.1 - 0.12 11.2 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) HTH_Tnp_Tc3_2 PF01498.13 CEP13574.1 - 1.4e-09 37.9 0.2 4.3e-09 36.3 0.0 1.9 2 1 0 2 2 2 1 Transposase HTH_28 PF13518.1 CEP13574.1 - 5.8e-05 23.0 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP13574.1 - 0.0087 16.2 0.0 0.027 14.6 0.0 1.8 2 1 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP13574.1 - 0.01 16.6 0.1 0.29 11.9 0.0 2.7 2 1 1 3 3 3 0 Homeodomain-like domain DDE_Tnp_1_7 PF13843.1 CEP13575.1 - 0.00031 19.9 0.0 0.00032 19.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.16 CEP13575.1 - 0.02 14.4 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1_7 PF13843.1 CEP13578.1 - 1.7e-27 96.4 0.0 2.6e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 RVT_1 PF00078.22 CEP13579.1 - 5.4e-15 55.3 0.0 6.4e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CEP13580.1 - 2.1e-06 27.7 0.1 9.4e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CEP13581.1 - 4.4e-05 23.9 0.1 8e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP13581.1 - 8.4e-05 22.3 0.0 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 CEP13581.1 - 0.00058 19.4 0.0 0.0014 18.1 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 CEP13581.1 - 0.075 12.5 0.2 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative peptidase (DUF1758) RVP_2 PF08284.6 CEP13581.1 - 0.087 12.7 0.2 0.19 11.6 0.1 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF2185 PF09951.4 CEP13582.1 - 0.05 13.3 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) DUF374 PF04028.8 CEP13582.1 - 0.084 12.1 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) rve PF00665.21 CEP13583.1 - 8e-21 74.3 0.0 1.7e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP13583.1 - 0.00092 18.6 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain NmrA PF05368.8 CEP13584.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Microtub_assoc PF07989.6 CEP13584.1 - 0.083 12.7 0.1 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Microtubule associated Histidinol_dh PF00815.15 CEP13584.1 - 0.11 11.0 0.8 0.58 8.7 0.1 1.9 2 0 0 2 2 2 0 Histidinol dehydrogenase DNA_pol_A_exo1 PF01612.15 CEP13585.1 - 0.00018 21.0 0.1 0.00049 19.6 0.0 1.8 1 0 0 1 1 1 1 3'-5' exonuclease tRNA-synt_2c PF01411.14 CEP13586.1 - 1.1e-212 707.2 0.0 1.7e-212 706.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CEP13586.1 - 2.8e-18 65.5 0.1 6.7e-18 64.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CEP13586.1 - 2.2e-08 33.6 1.1 7.2e-08 32.0 0.8 2.0 1 0 0 1 1 1 1 DHHA1 domain ECR1_N PF14382.1 CEP13587.1 - 3.4e-12 45.4 0.2 7.2e-12 44.3 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CEP13587.1 - 0.0029 17.5 0.2 0.13 12.2 0.1 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 GRAM PF02893.15 CEP13588.1 - 4.2e-28 96.6 1.9 6.2e-16 57.6 0.2 3.5 3 0 0 3 3 3 2 GRAM domain Glyco_transf_28 PF03033.15 CEP13588.1 - 3.9e-24 84.9 0.0 1.1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 CEP13588.1 - 4.7e-13 49.2 4.0 2.5e-11 43.7 0.2 4.0 5 0 0 5 5 5 1 PH domain UDPGT PF00201.13 CEP13588.1 - 1.7e-07 30.1 0.0 3.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.1 CEP13588.1 - 5.1e-07 29.6 0.4 2.1e-06 27.7 0.2 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Na_H_Exchanger PF00999.16 CEP13589.1 - 7.8e-26 90.4 11.6 9.5e-26 90.2 8.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 60KD_IMP PF02096.15 CEP13589.1 - 0.053 13.1 0.6 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 60Kd inner membrane protein ATPase_gene1 PF09527.5 CEP13589.1 - 0.089 12.6 0.6 0.089 12.6 0.4 3.2 5 0 0 5 5 5 0 Putative F0F1-ATPase subunit (ATPase_gene1) YrhC PF14143.1 CEP13589.1 - 4.2 7.3 8.8 0.092 12.7 0.8 2.2 3 0 0 3 3 3 0 YrhC-like protein DUF2754 PF10953.3 CEP13589.1 - 5.5 7.1 8.9 2.5 8.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2754) WW PF00397.21 CEP13590.1 - 0.00016 21.4 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 WW domain GAT PF03127.9 CEP13591.1 - 0.00054 19.8 0.3 0.00063 19.6 0.2 1.1 1 0 0 1 1 1 1 GAT domain DUF4032 PF13224.1 CEP13591.1 - 0.058 13.0 0.2 0.12 12.0 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4032) FAD_binding_1 PF00667.15 CEP13593.1 - 5.8e-54 182.8 0.0 9.1e-54 182.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CEP13593.1 - 1e-30 106.5 0.4 2.3e-30 105.4 0.1 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 CEP13593.1 - 6e-19 68.6 0.0 2.8e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CEP13593.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Nramp PF01566.13 CEP13595.1 - 4e-105 351.5 17.5 4e-105 351.5 12.1 2.0 1 1 1 2 2 2 2 Natural resistance-associated macrophage protein RhoGEF PF00621.15 CEP13596.1 - 1.2e-27 96.9 1.4 1.9e-27 96.2 0.3 1.9 2 0 0 2 2 2 1 RhoGEF domain CNH PF00780.17 CEP13596.1 - 2.6e-08 33.6 0.3 6.5e-08 32.3 0.2 1.7 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CEP13596.1 - 0.00016 21.6 1.3 0.00096 19.1 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain RVT_1 PF00078.22 CEP13597.1 - 1.7e-29 102.6 0.0 4.2e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP13597.1 - 2.9e-14 52.7 2.1 9.5e-14 51.0 0.8 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP13597.1 - 2e-05 24.6 0.1 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_int_SAM_4 PF13495.1 CEP13598.1 - 0.0052 17.0 0.9 0.01 16.1 0.6 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 CEP13598.1 - 0.68 10.1 4.7 0.29 11.3 1.3 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Opiods_neuropep PF01160.13 CEP13599.1 - 0.034 13.8 0.7 0.071 12.8 0.5 1.5 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Phage_endo_I PF05367.6 CEP13600.1 - 0.049 13.0 0.0 5 6.4 0.0 2.2 2 0 0 2 2 2 0 Phage endonuclease I PPV_E2_C PF00511.12 CEP13600.1 - 0.14 12.1 0.0 19 5.2 0.0 2.3 2 0 0 2 2 2 0 E2 (early) protein, C terminal Phage_int_SAM_3 PF14659.1 CEP13600.1 - 0.16 12.2 1.0 27 5.1 0.0 2.7 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.20 CEP13602.1 - 1e-57 195.2 0.1 1e-57 195.2 0.1 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13602.1 - 7.4e-22 77.6 0.2 5.2e-21 74.8 0.1 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CEP13602.1 - 0.0033 17.1 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RED_N PF07808.8 CEP13603.1 - 3.5e-39 134.4 22.8 3.5e-39 134.4 15.8 3.4 2 2 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.6 CEP13603.1 - 2.5e-20 72.8 12.5 2.5e-20 72.8 8.7 3.3 3 1 0 3 3 3 1 RED-like protein C-terminal region WD40 PF00400.27 CEP13604.1 - 1.8e-07 30.7 6.1 0.073 12.9 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CEP13604.1 - 0.0064 15.9 0.1 0.12 11.9 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 CEP13604.1 - 0.062 11.1 0.1 0.26 9.0 0.0 1.9 2 0 0 2 2 2 0 IKI3 family PD40 PF07676.7 CEP13604.1 - 0.083 12.5 0.1 8.7 6.1 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat KH_1 PF00013.24 CEP13605.1 - 0.12 12.0 0.0 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 KH domain CFEM PF05730.6 CEP13606.1 - 0.87 9.4 8.3 1.9 8.3 5.7 1.6 1 1 0 1 1 1 0 CFEM domain DUF935 PF06074.7 CEP13608.1 - 0.025 13.3 0.1 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) LsmAD PF06741.8 CEP13608.1 - 0.03 14.4 0.0 0.78 9.8 0.0 2.5 2 0 0 2 2 2 0 LsmAD domain Folate_carrier PF01770.13 CEP13609.1 - 0.052 12.0 1.5 0.076 11.5 1.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF4393 PF14337.1 CEP13609.1 - 0.14 11.5 12.2 0.38 10.1 8.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4393) SR-25 PF10500.4 CEP13609.1 - 0.3 10.5 10.2 0.51 9.7 7.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PA26 PF04636.8 CEP13609.1 - 1.2 7.7 9.0 1.7 7.2 6.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SAGA-Tad1 PF12767.2 CEP13609.1 - 1.3 8.6 15.9 1.9 8.0 11.1 1.3 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2347 PF09804.4 CEP13609.1 - 1.8 7.8 8.9 3.5 6.8 6.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) TT_ORF1 PF02956.9 CEP13609.1 - 2.4 6.4 6.7 3.1 6.1 4.7 1.1 1 0 0 1 1 1 0 TT viral orf 1 Aconitase_C PF00694.14 CEP13609.1 - 2.5 8.2 5.7 4.4 7.4 4.0 1.4 1 0 0 1 1 1 0 Aconitase C-terminal domain BTV_NS2 PF04514.7 CEP13609.1 - 2.8 6.7 8.7 4 6.2 6.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Chitin_synth_2 PF03142.10 CEP13610.1 - 4.5e-243 807.4 3.1 6e-243 807.0 2.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEP13610.1 - 4.3e-113 378.7 2.1 7.5e-113 377.9 1.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 CEP13610.1 - 6.3e-18 64.2 0.1 2.2e-16 59.3 0.1 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 CEP13610.1 - 1.7e-17 63.7 0.7 6.7e-17 61.8 0.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP13610.1 - 1.9e-16 60.5 0.0 3.5e-14 53.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CEP13610.1 - 2e-15 56.3 0.9 1.2e-07 31.3 0.0 3.8 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CEP13610.1 - 5.2e-06 26.2 0.0 0.00026 20.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP13610.1 - 6.4e-05 22.3 0.2 0.00026 20.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Jiv90 PF14901.1 CEP13610.1 - 0.13 12.2 0.2 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Cleavage inducing molecular chaperone Glutaredoxin PF00462.19 CEP13611.1 - 4e-24 84.3 0.4 7e-24 83.5 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 CEP13611.1 - 0.0014 18.8 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 CEP13611.1 - 0.0042 17.3 0.1 0.0061 16.7 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 CEP13611.1 - 0.0073 16.4 0.6 0.023 14.8 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CEP13611.1 - 0.0076 15.8 0.2 0.043 13.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 CEP13611.1 - 0.11 12.5 0.0 2.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin DSBA PF01323.15 CEP13611.1 - 0.11 11.9 0.3 0.38 10.2 0.1 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain PH PF00169.24 CEP13612.1 - 9.2e-09 35.4 1.3 2e-07 31.1 0.1 3.3 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 CEP13612.1 - 0.0025 17.2 0.0 0.0067 15.9 0.0 1.7 1 0 0 1 1 1 1 GRAM domain VPR PF00522.13 CEP13612.1 - 0.081 12.7 2.5 0.16 11.7 0.3 2.5 2 0 0 2 2 2 0 VPR/VPX protein Med5 PF08689.5 CEP13613.1 - 1.1e-15 56.5 1.4 1.1e-15 56.5 0.9 1.9 2 0 0 2 2 2 1 Mediator complex subunit Med5 Thiol-ester_cl PF10569.4 CEP13613.1 - 0.14 11.3 0.4 0.43 9.8 0.3 1.9 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region Arrestin_C PF02752.17 CEP13614.1 - 2.6e-12 47.0 0.3 6.2e-08 32.8 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP13614.1 - 2e-06 27.6 0.0 4.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF4097 PF13349.1 CEP13614.1 - 0.063 12.8 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) PEMT PF04191.8 CEP13615.1 - 8.8e-14 51.5 3.1 8.8e-14 51.5 2.2 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 CEP13615.1 - 1.1e-10 41.5 1.7 1.1e-10 41.5 1.2 2.1 1 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 CEP13615.1 - 2.5e-06 26.9 2.6 3.3e-06 26.5 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 CEP13615.1 - 0.03 14.0 2.5 0.049 13.3 1.2 1.8 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase PRA1 PF03208.14 CEP13615.1 - 0.13 11.6 13.7 0.26 10.6 3.8 2.1 2 0 0 2 2 2 0 PRA1 family protein adh_short PF00106.20 CEP13616.1 - 1.1e-24 87.2 0.0 1.9e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP13616.1 - 1.3e-14 54.5 0.0 1.7e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP13616.1 - 1.9e-10 40.7 0.0 2.8e-10 40.1 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CEP13616.1 - 3.6e-07 29.8 0.0 5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEP13616.1 - 1.2e-05 25.3 0.1 2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEP13616.1 - 0.00053 19.3 0.0 0.00091 18.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.5 CEP13616.1 - 0.0007 18.8 0.2 0.072 12.2 0.1 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 CEP13616.1 - 0.009 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain ADH_zinc_N PF00107.21 CEP13616.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 CEP13616.1 - 0.056 13.4 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain AIG1 PF04548.11 CEP13617.1 - 0.13 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 AIG1 family 2-Hacid_dh_C PF02826.14 CEP13618.1 - 1.5e-51 174.1 0.0 2e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEP13618.1 - 2.8e-33 114.1 0.0 3.3e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 CEP13618.1 - 0.0044 17.4 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CEP13618.1 - 0.0054 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 CEP13618.1 - 0.007 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CEP13618.1 - 0.017 15.2 0.0 0.052 13.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 CEP13618.1 - 0.026 15.0 0.0 0.078 13.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold HTH_OrfB_IS605 PF12323.3 CEP13618.1 - 0.026 13.8 0.1 6.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain IlvN PF07991.7 CEP13618.1 - 0.051 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain APC_CDC26 PF10471.4 CEP13619.1 - 0.15 12.7 10.6 0.28 11.9 7.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Pepsin-I3 PF06394.8 CEP13619.1 - 2 8.1 8.4 2.8 7.6 5.8 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain RCR PF12273.3 CEP13619.1 - 4.9 7.7 16.9 6.9 7.2 11.7 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red BAF1_ABF1 PF04684.8 CEP13619.1 - 8.2 5.1 9.7 7.9 5.2 6.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CBFD_NFYB_HMF PF00808.18 CEP13620.1 - 2.7e-08 33.7 0.1 3.7e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEP13620.1 - 0.00076 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2404 PF10296.4 CEP13621.1 - 3.1e-21 75.3 0.0 7.1e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 CEP13621.1 - 0.0056 16.8 0.9 0.0056 16.8 0.6 2.0 2 0 0 2 2 2 1 PH domain Beta_elim_lyase PF01212.16 CEP13622.1 - 1.5e-77 260.6 0.1 1.9e-77 260.2 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CEP13622.1 - 3.3e-07 29.6 0.1 5.1e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CEP13622.1 - 9.1e-06 24.9 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CEP13622.1 - 0.074 11.4 0.1 0.14 10.5 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain zf-RVT PF13966.1 CEP13623.1 - 0.044 14.0 0.4 0.11 12.7 0.3 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.22 CEP13624.1 - 6.2e-06 25.7 0.1 7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Urb2 PF10441.4 CEP13625.1 - 0.73 9.3 4.9 0.27 10.8 1.6 1.6 1 1 0 1 1 1 0 Urb2/Npa2 family Abhydrolase_6 PF12697.2 CEP13627.1 - 1e-21 77.8 0.0 1.4e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP13627.1 - 1.7e-09 37.5 0.0 5.5e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP13627.1 - 7e-09 35.5 0.0 1.1e-08 35.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CEP13627.1 - 1.1e-05 25.7 0.0 1.7e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 CEP13627.1 - 0.0001 21.9 0.3 0.002 17.7 0.2 2.1 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CEP13627.1 - 0.0053 16.0 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 CEP13627.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.9 CEP13627.1 - 0.028 12.9 0.0 0.057 11.8 0.0 1.6 1 1 0 1 1 1 0 Ndr family PhoD PF09423.5 CEP13627.1 - 0.046 12.2 0.0 0.069 11.7 0.0 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase bZIP_1 PF00170.16 CEP13628.1 - 6e-11 42.1 7.1 6e-11 42.1 5.0 2.7 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 CEP13628.1 - 1.8e-06 27.6 6.3 1.8e-06 27.6 4.4 2.9 2 1 1 3 3 3 1 Basic region leucine zipper Aft1_OSA PF11785.3 CEP13628.1 - 2.9e-05 24.5 4.2 2.9e-05 24.5 2.9 2.7 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain DUF1423 PF07227.6 CEP13628.1 - 0.00072 18.3 1.9 0.0012 17.5 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) bZIP_Maf PF03131.12 CEP13628.1 - 0.021 15.0 3.4 0.021 15.0 2.3 2.2 2 1 0 2 2 2 0 bZIP Maf transcription factor Paramyxo_C PF01692.13 CEP13628.1 - 7.3 6.1 9.6 1.6 8.2 3.0 2.0 1 1 1 2 2 2 0 Paramyxovirus non-structural protein c DDE_Tnp_1_7 PF13843.1 CEP13629.1 - 0.00014 21.0 0.0 0.00015 20.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Helitron_like_N PF14214.1 CEP13635.1 - 5.7e-23 81.5 0.0 9.9e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Sec23_helical PF04815.10 CEP13635.1 - 0.09 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 helical domain PIF1 PF05970.9 CEP13636.1 - 1e-55 189.1 0.0 2.3e-30 105.7 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 CEP13636.1 - 4.1e-08 31.4 0.0 5.5e-08 31.0 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP13636.1 - 0.0007 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ERp29 PF07749.7 CEP13637.1 - 0.021 15.4 0.1 0.022 15.3 0.1 1.3 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain bZIP_2 PF07716.10 CEP13638.1 - 7.4e-11 41.6 13.6 7.4e-11 41.6 9.4 2.0 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP13638.1 - 0.00031 20.6 12.3 0.00031 20.6 8.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor RRM_3 PF08777.6 CEP13638.1 - 0.023 14.5 3.9 0.041 13.7 2.7 1.5 1 0 0 1 1 1 0 RNA binding motif GAGA_bind PF06217.7 CEP13638.1 - 2 8.2 9.0 2.5 8.0 5.9 1.3 1 1 0 1 1 1 0 GAGA binding protein-like family XhlA PF10779.4 CEP13638.1 - 6.1 6.8 8.4 21 5.1 5.8 1.9 1 1 0 1 1 1 0 Haemolysin XhlA GST_N_3 PF13417.1 CEP13639.1 - 1.5e-19 69.9 0.0 5.1e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP13639.1 - 7e-14 51.5 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP13639.1 - 1.6e-10 41.0 0.0 4.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEP13639.1 - 7.4e-09 35.3 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP13639.1 - 4.2e-05 23.4 0.0 0.00012 22.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP13639.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-RING_2 PF13639.1 CEP13640.1 - 5.8e-13 48.4 8.7 9.8e-13 47.7 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 CEP13640.1 - 3.8e-08 32.9 0.0 8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.20 CEP13640.1 - 1.5e-06 27.7 7.2 2.6e-06 26.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEP13640.1 - 2.9e-06 27.2 2.5 6.6e-06 26.1 1.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CEP13640.1 - 0.00038 20.4 8.6 0.00066 19.6 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEP13640.1 - 0.026 14.3 3.3 0.054 13.3 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CEP13640.1 - 0.04 13.5 9.2 0.067 12.8 6.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP13640.1 - 0.11 12.2 7.0 0.18 11.5 4.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 CEP13640.1 - 2.6 8.1 7.2 4.7 7.2 5.0 1.4 1 0 0 1 1 1 0 RING-like domain SID-1_RNA_chan PF13965.1 CEP13640.1 - 3.2 5.7 5.0 6.2 4.8 0.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4557 PF15101.1 CEP13640.1 - 4.6 7.0 11.2 6.2 6.5 6.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF202 PF02656.10 CEP13641.1 - 1.9e-15 56.8 3.5 1.3e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.15 CEP13641.1 - 0.044 13.3 6.2 0.064 12.8 4.3 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Cytochrom_B561 PF03188.11 CEP13641.1 - 0.051 13.4 3.1 0.085 12.6 2.1 1.4 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 DUF1129 PF06570.6 CEP13641.1 - 0.11 11.8 0.5 0.13 11.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PGG PF13962.1 CEP13641.1 - 0.17 11.5 2.0 0.23 11.0 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function zf-DHHC PF01529.15 CEP13641.1 - 0.48 9.8 2.3 0.67 9.3 1.6 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1625 PF07787.7 CEP13641.1 - 0.92 8.7 6.9 0.4 9.8 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) SdpI PF13630.1 CEP13641.1 - 1.4 8.6 7.9 2.3 8.0 4.3 1.9 2 0 0 2 2 2 0 SdpI/YhfL protein family TPR_11 PF13414.1 CEP13642.1 - 1.3e-05 24.7 2.0 2.6e-05 23.7 1.4 1.6 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CEP13642.1 - 0.013 15.1 1.5 0.069 12.7 0.6 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP13642.1 - 0.02 14.8 0.5 0.53 10.2 0.3 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat DnaB PF00772.16 CEP13642.1 - 0.095 12.5 0.5 0.3 10.9 0.3 1.9 1 1 0 1 1 1 0 DnaB-like helicase N terminal domain DUF488 PF04343.8 CEP13642.1 - 0.37 11.1 2.5 1.3 9.3 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF488 TPR_2 PF07719.12 CEP13642.1 - 0.39 10.7 2.9 3.9 7.6 0.2 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3347 PF11827.3 CEP13642.1 - 3.1 7.7 8.4 5.8 6.8 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) CPSF_A PF03178.10 CEP13643.1 - 2.5e-91 306.1 0.0 1.3e-89 300.5 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 CEP13643.1 - 1.7e-79 267.2 0.0 2.6e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_Mid PF14783.1 CEP13643.1 - 0.065 13.0 0.0 6.5 6.5 0.0 2.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1241 PF06840.6 CEP13645.1 - 0.0069 15.6 0.0 0.0077 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) CoA_transf_3 PF02515.12 CEP13646.1 - 1.4e-53 181.0 0.0 1.9e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III OrfB_Zn_ribbon PF07282.6 CEP13646.1 - 0.0001 21.8 0.6 0.00019 20.9 0.4 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain ArfGap PF01412.13 CEP13647.1 - 7.3e-27 93.4 0.9 7.3e-27 93.4 0.6 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf NUDE_C PF04880.8 CEP13647.1 - 0.056 13.7 1.7 0.22 11.8 0.1 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region PLDc_2 PF13091.1 CEP13648.1 - 2.2e-10 40.3 2.6 9e-07 28.6 0.6 3.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CEP13648.1 - 9.7e-07 28.3 0.6 9.7e-07 28.3 0.4 2.6 3 0 0 3 3 3 1 Phospholipase D Active site motif PX PF00787.19 CEP13648.1 - 2.1e-06 27.5 0.0 6.7e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 PX domain TFIIF_alpha PF05793.7 CEP13648.1 - 0.59 8.4 21.2 1 7.6 14.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) APC_CDC26 PF10471.4 CEP13648.1 - 0.78 10.5 16.2 2.6 8.8 4.4 3.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 TATR PF03430.8 CEP13648.1 - 0.89 8.1 8.8 1.4 7.4 6.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Ima1_N PF09779.4 CEP13648.1 - 2.6 8.5 5.5 0.73 10.3 0.3 2.4 1 1 0 2 2 2 0 Ima1 N-terminal domain Nuf2 PF03800.9 CEP13649.1 - 1.9e-22 79.8 0.9 1.9e-22 79.8 0.6 2.5 2 1 1 3 3 3 1 Nuf2 family APG6 PF04111.7 CEP13649.1 - 0.12 11.3 33.1 0.25 10.3 8.6 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 CEP13649.1 - 1.1 9.1 39.3 0.58 10.0 5.8 4.0 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CEP13649.1 - 8.5 5.4 7.1 5.1 6.1 0.9 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Kelch_5 PF13854.1 CEP13651.1 - 2.7e-17 62.3 2.3 8.7e-05 22.3 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 CEP13651.1 - 2.8e-17 62.3 8.6 0.0052 16.9 0.0 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP13651.1 - 1.1e-16 60.3 3.7 0.0021 17.8 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP13651.1 - 1.6e-15 56.1 9.4 0.0015 18.2 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CEP13651.1 - 3.4e-15 55.4 8.7 4.9e-05 23.3 0.0 6.3 5 2 2 7 7 7 3 Kelch motif BTB PF00651.26 CEP13651.1 - 3.9e-15 55.8 0.0 1.2e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.20 CEP13651.1 - 5.5e-14 51.4 4.8 0.00089 18.7 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Dicty_REP PF05086.7 CEP13651.1 - 3 5.5 10.6 4.1 5.0 7.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 CEP13652.1 - 6e-71 238.6 0.2 6e-71 238.6 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13652.1 - 1e-49 168.9 0.1 1e-49 168.9 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 CEP13652.1 - 1e-20 73.8 0.0 2.6e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 CEP13652.1 - 1.8e-05 23.8 0.0 1.8e-05 23.8 0.0 1.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CEP13652.1 - 0.0057 16.4 1.8 0.031 13.9 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family G-7-MTase PF12803.2 CEP13652.1 - 0.26 10.3 4.5 0.44 9.6 3.1 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) IncA PF04156.9 CEP13652.1 - 0.36 10.3 18.0 0.63 9.6 12.5 1.3 1 0 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 CEP13652.1 - 1.7 7.9 14.1 3.3 6.9 9.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.4 CEP13652.1 - 2.6 6.8 13.5 4.1 6.2 9.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2414 PF10309.4 CEP13653.1 - 8.4e-16 57.4 0.0 1.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF3661 PF12400.3 CEP13654.1 - 1e-39 135.5 10.4 1.4e-39 135.1 7.2 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Polysacc_synt_3 PF13440.1 CEP13654.1 - 0.21 11.0 8.1 2.9 7.2 0.0 2.9 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Hanta_G2 PF01561.11 CEP13654.1 - 1.7 6.9 4.0 2.7 6.2 2.8 1.3 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 WD40 PF00400.27 CEP13655.1 - 7.3e-06 25.6 0.2 0.58 10.1 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 CEP13656.1 - 5.9e-29 98.8 11.5 1.5e-07 31.0 0.3 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CEP13656.1 - 0.0015 16.7 0.3 0.008 14.3 0.1 2.1 2 1 0 2 2 2 1 Nucleoporin Nup120/160 UPF0128 PF03673.8 CEP13656.1 - 0.042 13.1 0.5 0.089 12.0 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) AA_permease PF00324.16 CEP13657.1 - 2e-113 379.3 44.4 2.4e-113 379.0 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEP13657.1 - 4.4e-36 124.3 46.4 5.5e-36 124.0 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.22 CEP13658.1 - 2.7e-65 216.1 4.0 2.2e-21 75.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CWC25 PF12542.3 CEP13659.1 - 3.6e-24 85.0 5.3 3.6e-24 85.0 3.7 3.3 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 CEP13659.1 - 9.6e-15 54.3 13.3 9.6e-15 54.3 9.2 3.9 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF1754 PF08555.5 CEP13659.1 - 0.017 15.6 13.8 0.017 15.6 9.6 3.2 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Lyase_1 PF00206.15 CEP13660.1 - 1.1e-99 333.5 0.0 1.5e-99 333.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CEP13660.1 - 8.7e-28 96.2 0.1 1.7e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Pkinase PF00069.20 CEP13661.1 - 8.2e-58 195.5 0.0 1e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13661.1 - 5.5e-35 120.6 0.0 7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP13661.1 - 5.1e-05 22.4 0.1 9.7e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_Me_trans PF04252.8 CEP13662.1 - 2.4e-45 154.3 0.0 4.3e-45 153.5 0.0 1.4 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase GPI-anchored PF10342.4 CEP13663.1 - 0.0014 19.0 0.2 0.0028 18.0 0.1 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Meleagrin PF08189.6 CEP13663.1 - 0.18 11.2 0.5 2.1 7.9 0.0 2.5 3 0 0 3 3 3 0 Meleagrin/Cygnin family Asp PF00026.18 CEP13664.1 - 1.3e-84 284.1 3.3 1.6e-84 283.9 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP13664.1 - 3.4e-07 30.3 0.0 2.2e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP13664.1 - 3.1e-05 23.5 0.0 0.00013 21.5 0.0 2.0 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CEP13664.1 - 0.0036 17.7 0.1 4 7.9 0.0 3.2 3 1 0 3 3 3 2 Aspartyl protease RBFA PF02033.13 CEP13665.1 - 2.9e-09 36.8 0.0 4.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Ribosome-binding factor A DUF3436 PF11918.3 CEP13665.1 - 0.0053 16.9 2.1 7.6 6.8 0.0 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF3436) Ribosomal_L24e PF01246.15 CEP13666.1 - 1.7e-13 50.1 0.1 1.7e-13 50.1 0.1 1.9 2 1 2 4 4 4 1 Ribosomal protein L24e mit_SMPDase PF14724.1 CEP13667.1 - 0.00011 20.1 0.3 0.00043 18.2 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial-associated sphingomyelin phosphodiesterase Peptidase_M24 PF00557.19 CEP13668.1 - 8.6e-49 165.9 0.5 1.2e-48 165.5 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CEP13668.1 - 2.6e-10 40.9 0.0 4.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.19 CEP13669.1 - 1.1e-12 47.2 16.9 6.3e-11 41.5 11.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP13669.1 - 9.9e-05 21.2 17.7 0.019 13.7 12.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Ca_hom_mod PF14798.1 CEP13669.1 - 1.5 7.7 4.4 0.65 8.9 0.4 2.0 2 0 0 2 2 2 0 Calcium homeostasis modulator DUF4191 PF13829.1 CEP13669.1 - 8.6 5.4 7.2 0.48 9.5 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) OTCace PF00185.19 CEP13670.1 - 4.7e-46 156.5 0.0 7.1e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 CEP13670.1 - 8.5e-45 151.9 0.0 1.6e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OCD_Mu_crystall PF02423.10 CEP13670.1 - 0.021 13.5 0.5 0.031 13.0 0.3 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Aldo_ket_red PF00248.16 CEP13671.1 - 3.2e-51 173.8 0.0 4.1e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.17 CEP13672.1 - 0.0061 16.6 0.0 0.6 10.2 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DUF3327 PF11806.3 CEP13672.1 - 0.12 12.7 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) HSP70 PF00012.15 CEP13674.1 - 4.9e-84 282.3 22.1 4.9e-84 282.3 15.3 2.7 2 1 0 2 2 2 1 Hsp70 protein GTSE1_N PF15259.1 CEP13675.1 - 0.16 11.8 5.1 0.056 13.3 0.4 2.0 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 HAUS6_N PF14661.1 CEP13675.1 - 0.62 9.3 4.2 0.38 10.0 0.4 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4557 PF15101.1 CEP13676.1 - 0.006 16.4 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) DHHW PF14286.1 CEP13676.1 - 0.21 10.8 0.8 0.28 10.4 0.6 1.1 1 0 0 1 1 1 0 DHHW protein rve PF00665.21 CEP13677.1 - 4e-21 75.3 0.0 6.3e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP13677.1 - 0.00071 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_2 PF02914.10 CEP13677.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu transposase DDE_Tnp_IS240 PF13610.1 CEP13677.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 DDE domain MRP-L20 PF12824.2 CEP13681.1 - 0.013 15.4 0.3 0.014 15.3 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Thyroglobulin_1 PF00086.13 CEP13682.1 - 0.041 13.2 1.2 0.057 12.7 0.8 1.3 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat DUF2204 PF09970.4 CEP13683.1 - 0.11 11.9 0.3 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) Exo_endo_phos_2 PF14529.1 CEP13684.1 - 8.7e-14 51.1 1.8 2.6e-13 49.6 0.8 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP13684.1 - 7.5e-05 22.7 0.2 7.5e-05 22.7 0.1 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_76 PF03663.9 CEP13684.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 DUF3605 PF12239.3 CEP13684.1 - 0.1 12.4 0.3 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3605) DUF4645 PF15488.1 CEP13685.1 - 0.18 10.9 2.3 0.19 10.8 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4645) CotH PF08757.6 CEP13687.1 - 1.7e-38 132.6 0.0 2.6e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 CotH protein OMPdecase PF00215.19 CEP13688.1 - 2.8e-80 268.9 0.0 3.2e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family EXS PF03124.9 CEP13689.1 - 1.3e-59 201.9 17.6 1.5e-59 201.7 12.2 1.0 1 0 0 1 1 1 1 EXS family Tfb4 PF03850.9 CEP13690.1 - 0.018 14.2 0.2 0.024 13.9 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF4376 PF14301.1 CEP13690.1 - 0.049 13.7 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) G-alpha PF00503.15 CEP13691.1 - 5e-100 334.9 5.8 5.6e-100 334.7 4.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP13691.1 - 8.4e-10 38.1 0.2 3e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PhoPQ_related PF10142.4 CEP13691.1 - 0.031 12.7 0.0 0.045 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Ribosomal_S4 PF00163.14 CEP13692.1 - 6.3e-28 96.9 1.0 1.1e-27 96.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CEP13692.1 - 3.1e-13 48.9 1.4 3.1e-13 48.9 1.0 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 CEP13693.1 - 3.9e-43 145.2 4.0 5.9e-43 144.7 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1989 PF09347.5 CEP13693.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) LETM1 PF07766.8 CEP13694.1 - 2.1e-36 125.3 5.3 1e-33 116.5 3.6 2.1 1 1 0 1 1 1 1 LETM1-like protein SAP PF02037.22 CEP13694.1 - 0.0096 15.4 0.0 1.8 8.1 0.0 2.8 2 0 0 2 2 2 2 SAP domain ARL6IP6 PF15062.1 CEP13694.1 - 0.12 12.3 0.1 0.56 10.1 0.0 2.1 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix tRNA-synt_1e PF01406.14 CEP13696.1 - 7.2e-134 445.6 3.6 7.4e-134 445.5 1.2 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CEP13696.1 - 2.7e-09 36.1 7.5 8.7e-07 27.9 0.2 3.4 2 1 1 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CEP13696.1 - 5.5e-05 21.3 0.0 0.00028 19.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 CEP13696.1 - 0.00074 18.2 0.1 0.045 12.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 CEP13696.1 - 0.0016 17.2 3.1 0.018 13.6 0.0 3.2 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.6 CEP13696.1 - 0.0039 17.4 3.0 0.0041 17.3 0.1 2.5 2 0 0 2 2 2 1 DALR domain Ribonuc_red_sm PF00268.16 CEP13697.1 - 6.4e-120 399.3 4.3 7.8e-120 399.1 3.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1220 PF06758.8 CEP13697.1 - 0.16 11.8 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) Glyco_transf_15 PF01793.11 CEP13698.1 - 1.1e-132 442.0 11.2 1.3e-132 441.7 7.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase VTC PF09359.5 CEP13699.1 - 9.9e-69 231.4 0.3 2e-68 230.5 0.2 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEP13699.1 - 1.7e-24 87.0 4.9 1.1e-10 41.8 6.6 4.4 2 2 1 3 3 3 2 SPX domain DUF202 PF02656.10 CEP13699.1 - 6.3e-09 35.9 0.6 1.4e-08 34.8 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Pox_polyA_pol_N PF12630.2 CEP13699.1 - 0.5 10.4 5.1 0.18 11.9 0.4 2.6 3 0 0 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain Peptidase_M20 PF01546.23 CEP13700.1 - 9.2e-27 93.7 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 CEP13700.1 - 2.9e-21 74.4 15.9 6.4e-08 32.1 0.1 7.4 6 2 0 6 6 6 5 WD domain, G-beta repeat M20_dimer PF07687.9 CEP13700.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 CEP13700.1 - 1.9e-06 26.2 1.2 0.091 10.8 0.1 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 TMEM191C PF15194.1 CEP13700.1 - 0.12 12.3 0.0 13 5.6 0.0 3.2 3 1 1 4 4 4 0 TMEM191C family DUF3432 PF11914.3 CEP13701.1 - 0.18 11.8 8.6 0.31 11.0 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Herpes_capsid PF06112.6 CEP13701.1 - 3.2 7.7 7.5 4.2 7.3 5.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TFIID_20kDa PF03847.8 CEP13702.1 - 4.4e-35 119.7 0.7 7.6e-35 119.0 0.5 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 CEP13702.1 - 3.4e-05 23.8 0.1 7.1e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEP13702.1 - 8.3e-05 22.6 0.1 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PDZ_2 PF13180.1 CEP13702.1 - 0.079 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.20 CEP13703.1 - 6.4e-46 156.6 0.0 8.7e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13703.1 - 1.3e-17 63.7 0.0 1.9e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP13703.1 - 1.2e-05 24.4 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CPSase_L_D2 PF02786.12 CEP13704.1 - 3.9e-76 255.0 0.0 6.7e-76 254.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CEP13704.1 - 7.2e-40 135.5 0.0 1.7e-39 134.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CEP13704.1 - 2.4e-29 101.4 0.0 2.9e-28 97.9 0.0 2.5 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CEP13704.1 - 1.8e-17 62.7 1.1 4.4e-17 61.4 0.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CEP13704.1 - 1.9e-12 47.3 0.0 5e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CEP13704.1 - 1.7e-10 40.6 0.0 4.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CEP13704.1 - 4e-09 35.9 0.9 0.00097 18.7 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.1 CEP13704.1 - 5.7e-09 35.1 0.0 1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CEP13704.1 - 6.5e-07 28.8 0.0 1.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 CEP13704.1 - 1.1e-05 24.7 0.7 0.045 12.9 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 CEP13704.1 - 0.00042 20.2 0.1 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CEP13704.1 - 0.00074 19.8 1.7 0.029 14.7 0.1 3.3 3 0 0 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 CEP13704.1 - 0.001 18.4 0.8 0.18 11.1 0.1 2.3 1 1 1 2 2 2 2 HlyD family secretion protein MutH PF02976.10 CEP13704.1 - 0.1 12.4 0.3 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH Cas1_AcylT PF07779.7 CEP13705.1 - 3.7e-142 474.2 37.8 1.4e-141 472.3 26.2 1.7 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 CEP13705.1 - 4.6e-26 92.1 0.0 7.4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p XPG_I PF00867.13 CEP13706.1 - 0.0011 18.9 0.0 0.0056 16.6 0.0 2.3 1 1 0 1 1 1 1 XPG I-region Halogen_Hydrol PF10112.4 CEP13706.1 - 0.015 14.7 0.2 0.085 12.2 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein dCMP_cyt_deam_1 PF00383.17 CEP13707.1 - 3.4e-23 81.2 0.7 6.5e-23 80.3 0.5 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 CEP13707.1 - 0.0048 17.6 0.0 0.0091 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP13707.1 - 0.039 14.2 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.16 CEP13708.1 - 3.6e-254 844.9 7.2 3.6e-254 844.9 5.0 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.14 CEP13708.1 - 2.9e-06 26.8 0.4 8e-06 25.4 0.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Lebercilin PF15619.1 CEP13708.1 - 0.00013 21.4 12.9 0.00013 21.4 8.9 2.8 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 CEP13708.1 - 0.023 14.3 63.0 0.0092 15.5 19.2 3.7 1 1 0 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 CEP13708.1 - 0.025 13.7 17.1 0.018 14.2 6.4 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein AAA_16 PF13191.1 CEP13708.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain PIN_2 PF10130.4 CEP13708.1 - 1.5 8.8 9.3 0.45 10.5 3.1 2.5 1 1 1 2 2 2 0 PIN domain Med9 PF07544.8 CEP13708.1 - 2.9 7.6 34.7 0.57 9.9 1.0 6.1 2 1 4 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 DUF2404 PF10296.4 CEP13709.1 - 1.5e-06 28.2 0.1 3.6e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DDE_3 PF13358.1 CEP13710.1 - 1.1e-14 54.4 0.1 1.3e-06 28.2 0.1 2.7 1 1 1 2 2 2 2 DDE superfamily endonuclease Y_phosphatase PF00102.22 CEP13711.1 - 5.3e-65 219.0 6.6 5.3e-65 219.0 4.6 2.7 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CEP13711.1 - 5.6e-11 42.7 0.2 1.3e-09 38.3 0.0 2.9 2 1 1 3 3 3 1 Rhodanese-like domain DSPc PF00782.15 CEP13711.1 - 0.00032 20.2 0.2 0.001 18.6 0.2 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CEP13711.1 - 0.0084 16.1 1.8 0.24 11.4 0.1 2.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Vip3A_N PF12495.3 CEP13711.1 - 0.09 12.4 0.3 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF3567 PF12091.3 CEP13711.1 - 0.095 12.6 0.1 5.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) DUF4106 PF13388.1 CEP13711.1 - 0.45 9.4 9.3 0.85 8.5 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Y_phosphatase3 PF13350.1 CEP13711.1 - 1.4 9.1 5.4 0.21 11.8 0.2 2.3 3 0 0 3 3 3 0 Tyrosine phosphatase family Gastrin PF00918.12 CEP13711.1 - 2.3 9.0 7.1 4.2 8.1 0.0 2.9 3 0 0 3 3 3 0 Gastrin/cholecystokinin family NAD_binding_10 PF13460.1 CEP13712.1 - 0.00024 21.1 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUSP PF06337.7 CEP13712.1 - 0.099 13.0 0.7 2.3 8.6 0.5 3.1 1 1 0 1 1 1 0 DUSP domain NIF3 PF01784.13 CEP13713.1 - 7.1e-65 218.9 0.0 8.6e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Acyl-CoA_dh_1 PF00441.19 CEP13714.1 - 8.5e-47 159.0 3.1 8.5e-47 159.0 2.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEP13714.1 - 4.8e-26 91.5 0.6 1.9e-25 89.6 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEP13714.1 - 1.1e-21 77.5 0.4 1.1e-21 77.5 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEP13714.1 - 1.1e-18 66.4 0.0 2.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Exo_endo_phos PF03372.18 CEP13716.1 - 2.4e-18 66.9 0.0 3.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CEP13716.1 - 1.6e-12 46.7 12.1 5e-06 26.0 2.4 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP13716.1 - 1.7e-07 30.8 11.0 1.5e-05 24.6 2.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CEP13716.1 - 2.3e-07 29.8 10.4 0.39 10.9 0.0 5.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CEP13716.1 - 0.0019 18.0 10.9 13 6.5 0.9 5.0 4 0 0 4 4 4 3 Leucine rich repeat Sec6 PF06046.8 CEP13718.1 - 6.1e-144 480.2 10.2 1e-143 479.4 7.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec6 Prok-E2_A PF14457.1 CEP13718.1 - 0.004 16.6 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family A NPV_P10 PF05531.7 CEP13718.1 - 0.31 11.2 3.7 24 5.2 0.4 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein OrfB_Zn_ribbon PF07282.6 CEP13719.1 - 1.8e-07 30.6 1.2 3.5e-07 29.7 0.8 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DUF2652 PF10851.3 CEP13719.1 - 0.012 15.6 0.3 0.014 15.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) RuBisCO_large PF00016.15 CEP13719.1 - 0.014 14.2 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Zn_Tnp_IS1595 PF12760.2 CEP13719.1 - 0.082 12.7 0.8 0.13 12.0 0.6 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain UPF0081 PF03652.10 CEP13719.1 - 0.09 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) C1_1 PF00130.17 CEP13719.1 - 0.37 10.5 3.3 0.2 11.3 0.7 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TFIIS_C PF01096.13 CEP13719.1 - 1.9 8.1 5.5 9.5 5.9 0.3 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_5 PF13719.1 CEP13719.1 - 8.7 6.0 7.9 71 3.0 5.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain PLDc PF00614.17 CEP13720.1 - 7.7e-19 66.8 2.1 2.9e-11 42.8 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CEP13720.1 - 7.1e-14 51.6 0.2 5.5e-07 29.3 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain DDE_3 PF13358.1 CEP13721.1 - 1.5e-05 24.8 0.1 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP13721.1 - 0.022 14.9 0.0 0.2 11.8 0.0 2.1 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.1 CEP13721.1 - 0.022 14.7 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.1 CEP13721.1 - 0.099 13.4 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Amino_oxidase PF01593.19 CEP13721.1 - 0.14 11.2 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Methyltransf_7 PF03492.10 CEP13725.1 - 0.0055 15.5 0.1 0.0082 14.9 0.0 1.2 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase NDT80_PhoG PF05224.7 CEP13726.1 - 1.5e-39 135.9 0.0 3.2e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF1180 PF06679.7 CEP13726.1 - 0.25 11.2 2.5 14 5.5 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Aconitase_C PF00694.14 CEP13727.1 - 0.72 9.9 3.3 4.9 7.2 0.7 2.8 3 0 0 3 3 3 0 Aconitase C-terminal domain Trs65 PF12735.2 CEP13729.1 - 0.013 14.8 0.1 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 PWI PF01480.12 CEP13732.1 - 1.6e-29 101.8 0.0 3.4e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain CAP_GLY PF01302.20 CEP13733.1 - 1.5e-21 75.8 0.2 2.4e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.26 CEP13733.1 - 1.7e-10 40.8 0.4 3.8e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain MRG PF05712.8 CEP13733.1 - 0.078 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 MRG PBP1_TM PF14812.1 CEP13733.1 - 0.21 11.8 4.6 0.5 10.7 3.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vac7 PF12751.2 CEP13734.1 - 4e-05 22.6 0.1 4e-05 22.6 0.1 2.8 2 1 1 3 3 3 1 Vacuolar segregation subunit 7 Pyridox_oxase_2 PF12766.2 CEP13735.1 - 5.4e-27 94.0 0.9 1.1e-25 89.8 0.0 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 CEP13735.1 - 5.6e-10 39.0 0.0 8.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1955 PF09205.5 CEP13735.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1955) HTH_23 PF13384.1 CEP13736.1 - 8.4e-06 25.2 0.7 0.0042 16.6 0.0 2.7 3 0 0 3 3 3 2 Homeodomain-like domain HTH_17 PF12728.2 CEP13736.1 - 1e-05 25.6 0.0 0.076 13.2 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_28 PF13518.1 CEP13736.1 - 1.1e-05 25.3 2.6 0.00022 21.1 0.1 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP13736.1 - 3.2e-05 24.0 0.0 7.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_22 PF13309.1 CEP13736.1 - 0.1 12.3 0.1 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 HTH domain HTH_38 PF13936.1 CEP13736.1 - 0.14 11.7 0.0 5.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DTHCT PF08070.6 CEP13737.1 - 0.085 13.5 0.6 0.13 12.9 0.4 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region MARVEL PF01284.18 CEP13738.1 - 0.0046 16.7 13.6 0.0083 15.9 9.5 1.4 1 1 0 1 1 1 1 Membrane-associating domain TMEM107 PF14995.1 CEP13738.1 - 0.03 14.4 1.6 0.037 14.1 0.1 1.8 1 1 0 1 1 1 0 Transmembrane protein DUF378 PF04070.7 CEP13738.1 - 0.05 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF378) DUF3671 PF12420.3 CEP13738.1 - 0.06 13.3 0.3 0.06 13.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function RhodobacterPufX PF11511.3 CEP13738.1 - 0.15 11.5 0.1 0.15 11.5 0.1 2.7 4 0 0 4 4 4 0 Intrinsic membrane protein PufX DUF588 PF04535.7 CEP13739.1 - 0.0088 15.6 2.1 0.012 15.2 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF588) RNA_pol_Rpb4 PF03874.11 CEP13739.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 MARVEL PF01284.18 CEP13739.1 - 0.26 11.1 7.7 0.44 10.3 5.4 1.4 1 1 0 1 1 1 0 Membrane-associating domain ThiF PF00899.16 CEP13740.1 - 3.3e-36 124.0 0.1 6.1e-36 123.2 0.1 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CEP13740.1 - 6.5e-22 76.9 0.2 1.1e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CEP13740.1 - 1.8e-11 44.3 0.4 4.1e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.15 CEP13740.1 - 0.015 15.4 0.2 0.12 12.5 0.1 2.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RVT_1 PF00078.22 CEP13743.1 - 3.2e-09 36.4 0.7 6.4e-09 35.4 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SURNod19 PF07712.7 CEP13743.1 - 0.1 11.0 0.2 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 Stress up-regulated Nod 19 PfkB PF00294.19 CEP13744.1 - 4.6e-22 78.5 0.0 5.4e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PIP5K PF01504.13 CEP13745.1 - 6e-86 287.6 0.7 8.4e-86 287.1 0.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FMN_red PF03358.10 CEP13746.1 - 1.7e-11 43.8 0.1 1.7e-11 43.8 0.0 2.0 3 0 0 3 3 3 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CEP13746.1 - 0.00015 21.3 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CEP13747.1 - 1.5e-14 53.7 0.1 2.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CEP13747.1 - 1.6e-08 34.2 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 CEP13747.1 - 5.9e-06 26.3 0.1 1.6e-05 24.9 0.0 1.7 1 1 1 2 2 2 1 Flavodoxin BRCA-2_OB1 PF09103.5 CEP13748.1 - 6.3e-28 96.8 0.2 1.3e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 CEP13748.1 - 2e-11 43.8 0.6 8e-11 41.8 0.3 2.0 1 1 0 1 1 1 1 BRCA2, helical Rep-A_N PF04057.7 CEP13748.1 - 0.00015 21.4 0.1 0.0004 20.1 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain BRCA2 PF00634.13 CEP13748.1 - 0.5 9.6 6.9 3.2 7.1 0.0 2.8 3 0 0 3 3 3 0 BRCA2 repeat Sds3 PF08598.6 CEP13749.1 - 1.8e-08 34.1 15.8 1.8e-08 34.1 10.9 2.7 1 1 1 2 2 2 1 Sds3-like UMP1 PF05348.6 CEP13749.1 - 1 9.3 9.5 0.077 12.9 2.1 2.3 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 ATP12 PF07542.6 CEP13750.1 - 8e-37 125.8 0.6 1.2e-36 125.2 0.4 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DUF438 PF04282.8 CEP13750.1 - 0.0087 15.8 0.2 0.033 13.9 0.1 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF438) GCR1_C PF12550.3 CEP13751.1 - 2.5e-11 43.2 0.3 7e-11 41.8 0.2 1.8 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Baculo_PEP_C PF04513.7 CEP13751.1 - 0.039 13.7 3.4 0.076 12.8 2.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_29 PF13551.1 CEP13752.1 - 1.3e-06 28.4 0.0 2.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.1 CEP13752.1 - 4.7e-06 25.8 0.2 4.6e-05 22.7 0.1 2.4 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 CEP13752.1 - 0.00033 20.1 0.0 0.00085 18.8 0.0 1.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.2 CEP13752.1 - 0.00079 19.1 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.1 CEP13752.1 - 0.0012 19.5 0.1 0.016 15.9 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain HTH_5 PF01022.15 CEP13752.1 - 0.0018 17.8 0.0 0.036 13.7 0.0 2.6 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family Mga PF05043.8 CEP13752.1 - 0.0022 18.2 0.3 0.0044 17.2 0.2 1.5 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_IclR PF09339.5 CEP13752.1 - 0.0031 17.0 0.0 0.0076 15.8 0.0 1.7 2 0 0 2 2 1 1 IclR helix-turn-helix domain HTH_28 PF13518.1 CEP13752.1 - 0.0041 17.0 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.18 CEP13752.1 - 0.0046 16.7 0.1 0.087 12.6 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.1 CEP13752.1 - 0.0047 16.5 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 1 1 Homeodomain-like domain DUF134 PF02001.11 CEP13752.1 - 0.0056 16.5 0.1 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF134 Sigma70_r4_2 PF08281.7 CEP13752.1 - 0.0088 15.4 0.1 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 MarR_2 PF12802.2 CEP13752.1 - 0.016 14.8 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 MarR family Peptidase_M16 PF00675.15 CEP13752.1 - 0.016 14.9 0.0 0.039 13.7 0.0 1.6 1 1 0 1 1 1 0 Insulinase (Peptidase family M16) HTH_1 PF00126.22 CEP13752.1 - 0.022 14.4 0.1 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family MarR PF01047.17 CEP13752.1 - 0.024 14.3 0.1 0.064 12.9 0.0 1.7 2 0 0 2 2 1 0 MarR family NUMOD1 PF07453.8 CEP13752.1 - 0.032 14.0 1.2 0.35 10.7 0.1 2.9 2 1 1 3 3 3 0 NUMOD1 domain HTH_30 PF13556.1 CEP13752.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_6 PF01418.12 CEP13752.1 - 0.057 13.1 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Luteo_P1-P2 PF08467.5 CEP13752.1 - 0.059 12.1 1.0 0.079 11.7 0.7 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase PqqD PF05402.7 CEP13752.1 - 0.075 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) HTH_DeoR PF08220.7 CEP13752.1 - 0.083 12.4 0.0 4.6 6.8 0.0 2.4 2 1 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_8 PF02954.14 CEP13752.1 - 0.09 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family CBS PF00571.23 CEP13753.1 - 2.1e-29 101.0 1.7 2.3e-09 36.8 0.0 4.8 4 1 0 4 4 4 4 CBS domain CoA_binding_2 PF13380.1 CEP13753.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain RTBV_P46 PF06216.6 CEP13753.1 - 0.077 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein HlyIII PF03006.15 CEP13754.1 - 5.3e-60 202.5 22.9 6.7e-60 202.2 15.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related FadA PF09403.5 CEP13754.1 - 0.86 9.6 5.9 1.2 9.1 0.2 2.6 1 1 1 2 2 2 0 Adhesion protein FadA TFIID-18kDa PF02269.11 CEP13755.1 - 5.8e-31 106.1 0.3 1.5e-30 104.8 0.2 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Prok-E2_B PF14461.1 CEP13755.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Bromodomain PF00439.20 CEP13756.1 - 4e-23 81.1 0.1 8.4e-23 80.1 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Zn_clus PF00172.13 CEP13757.1 - 2.2e-07 30.6 9.0 2.2e-07 30.6 6.2 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM72 PF14976.1 CEP13758.1 - 1.9e-17 63.5 0.2 2.9e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 FAM72 protein TFIIA PF03153.8 CEP13759.1 - 1.3 8.8 6.9 1.5 8.6 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2254 PF10011.4 CEP13760.1 - 0.021 13.3 0.2 0.059 11.8 0.2 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) O-antigen_lig PF13425.1 CEP13760.1 - 0.054 13.4 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Avl9 PF09794.4 CEP13761.1 - 1.3e-138 461.5 0.1 2.9e-138 460.4 0.0 1.6 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.5 CEP13761.1 - 1.5e-11 44.0 0.1 8.2e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 CEP13761.1 - 3.7e-08 33.0 8.0 1.2e-06 28.0 0.0 4.9 2 2 2 4 4 4 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 CEP13761.1 - 0.12 12.0 0.4 1.1 8.9 0.0 2.6 3 0 0 3 3 3 0 DENN (AEX-3) domain Afi1 PF07792.7 CEP13761.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.4 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RIO1 PF01163.17 CEP13763.1 - 7.2e-46 155.9 0.0 7.2e-46 155.9 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 CEP13763.1 - 8.6e-36 121.8 1.0 2.6e-35 120.3 0.2 2.3 3 0 0 3 3 3 1 Rio2, N-terminal APH PF01636.18 CEP13763.1 - 1.4e-09 38.0 0.0 7.9e-05 22.5 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEP13763.1 - 5.7e-06 25.5 0.0 0.075 12.0 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SGT1 PF07093.6 CEP13763.1 - 0.23 9.8 33.4 0.35 9.1 23.2 1.2 1 0 0 1 1 1 0 SGT1 protein Pkinase PF00069.20 CEP13763.1 - 0.46 9.6 6.0 0.07 12.2 0.2 2.4 2 1 0 2 2 2 0 Protein kinase domain Voldacs PF03517.8 CEP13763.1 - 0.74 9.6 14.0 1.4 8.8 9.7 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling ATP-synt_B PF00430.13 CEP13764.1 - 0.16 11.7 0.2 0.16 11.7 0.1 6.0 3 2 3 6 6 6 0 ATP synthase B/B' CF(0) WD40 PF00400.27 CEP13765.1 - 4.8e-15 54.7 3.0 2.2e-05 24.1 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CEP13765.1 - 0.0095 15.4 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 CEP13765.1 - 0.014 13.5 0.0 1.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CEP13765.1 - 0.071 13.4 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.27 CEP13766.1 - 1.8e-39 132.1 8.4 1e-08 34.7 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CEP13766.1 - 6.8e-28 96.3 0.4 1.7e-27 95.0 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Macoilin PF09726.4 CEP13766.1 - 2.5 6.2 14.9 4.1 5.5 10.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 CEP13766.1 - 4.6 6.1 6.0 7.3 5.4 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ANF_receptor PF01094.23 CEP13767.1 - 5.4e-33 114.2 3.2 2e-32 112.3 2.2 1.8 1 1 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 CEP13767.1 - 5.5e-17 61.9 19.4 9.9e-17 61.0 13.4 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.1 CEP13767.1 - 5.3e-15 55.6 0.8 9.2e-15 54.8 0.6 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Aminotran_1_2 PF00155.16 CEP13768.1 - 2.4e-38 132.0 0.0 3.2e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEP13768.1 - 0.00071 18.8 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase HEAT_2 PF13646.1 CEP13770.1 - 1.9e-29 101.7 2.2 1.3e-09 38.2 0.1 8.8 4 3 4 8 8 8 7 HEAT repeats HEAT_EZ PF13513.1 CEP13770.1 - 4.6e-27 93.7 12.2 2.5e-08 34.1 0.1 12.6 9 2 5 14 14 14 6 HEAT-like repeat HEAT PF02985.17 CEP13770.1 - 1.1e-26 90.4 9.6 4.2e-05 23.2 0.1 10.8 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.2 CEP13770.1 - 6.3e-12 45.7 6.1 0.0027 18.0 0.0 8.0 7 1 2 10 10 9 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CEP13770.1 - 1e-09 38.1 0.7 0.0065 15.8 0.0 6.3 5 2 2 7 7 7 2 CLASP N terminal IBN_N PF03810.14 CEP13770.1 - 2.2e-08 33.9 1.3 2.9e-07 30.2 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 CEP13770.1 - 4.8e-08 31.7 2.0 0.014 13.7 0.1 4.4 4 1 1 5 5 5 2 Adaptin N terminal region Cnd1 PF12717.2 CEP13770.1 - 1.2e-07 31.7 0.9 0.0066 16.3 0.0 5.0 4 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.3 CEP13770.1 - 9.6e-06 25.6 1.4 0.1 12.5 0.0 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) DUF2454 PF10521.4 CEP13770.1 - 0.00071 18.6 0.3 0.057 12.4 0.0 4.0 4 1 1 5 5 5 1 Protein of unknown function (DUF2454) MMS19_C PF12460.3 CEP13770.1 - 0.0017 17.1 2.8 0.56 8.8 0.3 4.8 4 2 2 6 6 6 1 RNAPII transcription regulator C-terminal DUF2435 PF10363.4 CEP13770.1 - 0.0024 17.7 1.5 2 8.3 0.0 4.8 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) Katanin_con80 PF13925.1 CEP13770.1 - 0.041 13.6 0.3 4.5 6.9 0.0 3.4 3 0 0 3 3 3 0 con80 domain of Katanin Arm PF00514.18 CEP13770.1 - 0.043 13.6 5.9 4.7 7.1 0.0 6.3 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 CEP13770.1 - 0.054 13.4 0.6 3.2 7.7 0.0 4.1 4 1 1 5 5 4 0 Rix1 complex component involved in 60S ribosome maturation COX15-CtaA PF02628.10 CEP13771.1 - 3.8e-91 305.0 4.8 4.7e-91 304.8 3.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF943 PF06092.7 CEP13772.1 - 0.026 13.8 0.3 0.035 13.3 0.2 1.5 1 1 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) HTH_29 PF13551.1 CEP13773.1 - 2.9e-05 24.1 0.0 5.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP13773.1 - 3.4e-05 24.5 0.0 7.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 CEP13773.1 - 5.3e-05 22.9 0.4 0.82 9.5 0.2 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 CEP13773.1 - 0.00018 20.8 0.0 0.00042 19.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_17 PF12728.2 CEP13773.1 - 0.0033 17.6 0.3 4.5 7.6 0.0 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP13773.1 - 0.0037 16.8 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP13773.1 - 0.005 16.8 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain MerR_1 PF13411.1 CEP13773.1 - 0.027 14.2 0.5 0.26 11.0 0.3 2.3 1 1 1 2 2 2 0 MerR HTH family regulatory protein NUMOD1 PF07453.8 CEP13773.1 - 0.035 13.9 1.5 28 4.7 0.0 3.8 4 0 0 4 4 4 0 NUMOD1 domain HTH_Tnp_1 PF01527.15 CEP13773.1 - 0.1 12.6 0.0 0.81 9.6 0.0 2.2 2 0 0 2 2 2 0 Transposase Chromo PF00385.19 CEP13774.1 - 2.5e-09 36.6 0.2 4.2e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C97 PF05903.9 CEP13775.1 - 4.5e-42 143.3 0.0 9.9e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 CEP13775.1 - 2.7e-26 91.9 8.5 4e-26 91.4 5.9 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 CEP13775.1 - 5.3e-12 45.3 0.1 1.2e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 CEP13775.1 - 0.00056 19.4 0.2 0.0058 16.1 0.0 2.2 2 0 0 2 2 2 1 Redoxin Thioredoxin_8 PF13905.1 CEP13775.1 - 0.0006 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CEP13775.1 - 0.00086 19.4 0.3 0.013 15.6 0.2 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CEP13775.1 - 0.0017 18.0 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 CEP13775.1 - 0.018 15.0 0.0 0.058 13.4 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Med2 PF11214.3 CEP13775.1 - 0.15 12.1 3.6 0.17 11.9 0.1 2.7 4 0 0 4 4 4 0 Mediator complex subunit 2 DUF775 PF05603.7 CEP13776.1 - 1.4e-47 161.8 0.1 2.5e-47 161.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF775) 2OG-FeII_Oxy_2 PF13532.1 CEP13776.1 - 1.9e-35 122.4 0.0 2.3e-34 118.9 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TcpQ PF10671.4 CEP13776.1 - 0.098 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Yip1 PF04893.12 CEP13777.1 - 5.8e-08 32.4 16.3 1.1e-07 31.5 11.3 1.5 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.10 CEP13777.1 - 0.14 11.3 9.8 0.21 10.7 6.8 1.4 1 1 0 1 1 1 0 YIF1 Peptidase_M16 PF00675.15 CEP13778.1 - 1.9e-41 141.2 0.2 1.6e-40 138.2 0.1 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CEP13778.1 - 2.5e-33 115.3 0.2 5.5e-20 71.8 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain DDE_3 PF13358.1 CEP13779.1 - 8e-29 100.2 0.0 3.5e-28 98.1 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP13779.1 - 3.6e-05 23.8 0.0 8.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP13779.1 - 0.0077 15.8 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.21 CEP13779.1 - 0.012 15.7 0.0 0.37 10.9 0.0 2.8 3 0 0 3 3 3 0 Integrase core domain HTH_17 PF12728.2 CEP13779.1 - 0.054 13.7 0.1 0.52 10.5 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DUF496 PF04363.7 CEP13779.1 - 0.06 13.1 0.1 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF496) HTH_28 PF13518.1 CEP13779.1 - 0.14 12.2 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MerR_1 PF13411.1 CEP13779.1 - 0.2 11.4 1.5 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein Malic_M PF03949.10 CEP13780.1 - 7.7e-85 284.4 0.0 1.3e-84 283.7 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CEP13780.1 - 3.2e-72 241.9 0.0 6.9e-72 240.8 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Amino_oxidase PF01593.19 CEP13781.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF2547 PF10818.3 CEP13781.1 - 0.22 12.1 9.7 0.27 11.8 3.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2547) Recep_L_domain PF01030.19 CEP13782.1 - 0.13 12.2 4.9 0.22 11.5 0.5 3.1 3 2 1 4 4 4 0 Receptor L domain Sugar_tr PF00083.19 CEP13783.1 - 5.1e-35 120.9 35.5 1.2e-21 76.8 7.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP13783.1 - 2e-17 62.9 61.2 7.7e-16 57.7 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_4 PF12799.2 CEP13784.1 - 0.00049 19.6 5.4 0.17 11.5 0.6 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CEP13784.1 - 0.00065 19.5 9.4 0.18 12.0 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 CEP13784.1 - 3.9 7.2 6.2 25 4.7 0.7 2.9 2 0 0 2 2 2 0 Leucine rich repeat Ribosomal_S9 PF00380.14 CEP13785.1 - 5.5e-37 126.6 0.1 6.3e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 14-3-3 PF00244.15 CEP13786.1 - 1e-112 374.9 6.5 1.2e-112 374.7 4.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 CEP13786.1 - 0.072 13.0 2.2 0.9 9.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Syja_N PF02383.13 CEP13787.1 - 1e-92 310.3 0.5 1e-92 310.3 0.3 2.1 3 1 1 4 4 4 1 SacI homology domain Syja_N PF02383.13 CEP13788.1 - 4.9e-84 281.8 1.4 6.3e-84 281.4 1.0 1.1 1 0 0 1 1 1 1 SacI homology domain LRR_4 PF12799.2 CEP13789.1 - 9.2e-12 44.3 15.9 1.2e-06 27.9 1.6 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP13789.1 - 8.1e-08 31.9 12.4 0.00043 19.9 4.0 2.9 2 0 0 2 2 2 2 Leucine rich repeat Ubiquitin_2 PF14560.1 CEP13789.1 - 9.8e-06 25.7 0.6 3.3e-05 24.0 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_6 PF13516.1 CEP13789.1 - 1.2e-05 24.8 10.0 0.72 10.1 0.1 5.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.1 CEP13789.1 - 4.8e-05 22.9 0.3 4.8e-05 22.9 0.2 1.9 2 0 0 2 2 2 1 Leucine-rich repeat LRR_7 PF13504.1 CEP13789.1 - 0.0028 17.5 11.6 6.4 7.4 0.0 5.9 6 0 0 6 6 6 2 Leucine rich repeat ubiquitin PF00240.18 CEP13789.1 - 0.0031 16.8 1.1 0.027 13.8 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin family LRR_1 PF00560.28 CEP13789.1 - 0.039 13.9 13.4 7.1 7.0 0.5 5.4 2 1 2 4 4 4 0 Leucine Rich Repeat Glyco_trans_1_3 PF13528.1 CEP13790.1 - 5.5e-11 42.2 0.0 7.7e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 tRNA-synt_2b PF00587.20 CEP13791.1 - 5.8e-30 104.1 0.0 9.5e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CEP13791.1 - 1.7e-10 40.8 3.9 1.7e-10 40.8 2.7 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CAP_GLY PF01302.20 CEP13792.1 - 1.3e-20 72.8 0.3 2.1e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain FA_desaturase PF00487.19 CEP13793.1 - 5.8e-28 98.0 21.0 7.8e-28 97.6 14.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CEP13793.1 - 1.9e-07 31.1 0.0 4.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Eaf7 PF07904.8 CEP13794.1 - 1.2e-21 76.4 0.2 2.2e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 PPR_2 PF13041.1 CEP13795.1 - 6.1e-24 83.7 1.5 7.7e-07 28.9 0.0 10.1 8 2 2 10 10 10 3 PPR repeat family PPR_3 PF13812.1 CEP13795.1 - 1e-20 72.1 4.9 0.0061 16.7 0.0 10.6 12 0 0 12 12 12 3 Pentatricopeptide repeat domain PPR PF01535.15 CEP13795.1 - 2.8e-13 48.8 8.5 0.042 13.8 0.0 10.2 11 0 0 11 11 11 2 PPR repeat PPR_1 PF12854.2 CEP13795.1 - 3.2e-09 36.1 1.0 5.5e-05 22.5 0.0 5.6 7 0 0 7 7 7 1 PPR repeat TPR_14 PF13428.1 CEP13795.1 - 1.8e-05 24.9 0.2 1.9 9.3 0.0 5.8 6 2 2 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 CEP13795.1 - 3.1e-05 24.0 0.6 0.14 12.3 0.0 4.6 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 CEP13795.1 - 0.0047 17.2 0.0 26 5.1 0.1 3.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_2 PF07719.12 CEP13795.1 - 0.053 13.4 0.1 30 4.8 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Hydrolase_6 PF13344.1 CEP13796.1 - 2e-24 85.3 0.0 7.7e-24 83.5 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP13796.1 - 7e-20 70.5 0.0 2.9e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 CEP13796.1 - 6.9e-05 23.1 0.0 0.017 15.3 0.0 2.8 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP13796.1 - 0.00017 22.0 0.0 0.2 12.0 0.0 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Kinesin PF00225.18 CEP13797.1 - 3.8e-103 344.7 0.2 3.8e-103 344.7 0.1 2.8 2 1 0 2 2 2 1 Kinesin motor domain OTU PF02338.14 CEP13799.1 - 4.4e-13 49.8 2.8 1.3e-12 48.3 1.9 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 CEP13799.1 - 0.057 12.9 0.1 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 CUE domain ACT_3 PF10000.4 CEP13801.1 - 0.097 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 ACT domain DDE_3 PF13358.1 CEP13802.1 - 1.6e-07 31.1 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Potyvirid-P3 PF13608.1 CEP13803.1 - 0.13 11.3 2.1 0.13 11.3 1.5 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DDE_3 PF13358.1 CEP13804.1 - 0.0022 17.7 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3486 PF11985.3 CEP13804.1 - 0.01 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) DUF4080 PF13311.1 CEP13805.1 - 1.2 9.0 4.2 3.3 7.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Methyltransf_23 PF13489.1 CEP13806.1 - 2.4e-07 30.5 0.0 1e-06 28.5 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP13806.1 - 2.8e-07 30.9 0.0 6.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP13806.1 - 8.3e-05 22.2 0.1 0.00054 19.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP13806.1 - 0.0036 17.7 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP13806.1 - 0.0059 15.6 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 CEP13806.1 - 0.011 14.1 0.5 0.027 12.8 0.2 1.6 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 CEP13806.1 - 0.03 14.8 0.1 0.16 12.5 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CEP13806.1 - 0.064 13.2 0.1 0.39 10.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CEP13806.1 - 0.12 12.7 0.1 0.36 11.2 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Cyt-b5 PF00173.23 CEP13807.1 - 1.3e-22 79.3 0.0 1.4e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 CEP13807.1 - 0.0079 16.1 0.1 0.0082 16.0 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H Myb_DNA-binding PF00249.26 CEP13808.1 - 6.7e-05 22.8 0.2 0.00014 21.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP13808.1 - 0.00045 20.2 0.1 0.00045 20.2 0.0 2.9 2 1 0 2 2 2 1 Myb-like DNA-binding domain NifW PF03206.9 CEP13808.1 - 0.3 11.2 11.7 3.2 7.9 6.7 2.6 2 0 0 2 2 2 0 Nitrogen fixation protein NifW Aa_trans PF01490.13 CEP13809.1 - 1.3e-76 257.6 19.3 1.6e-76 257.4 13.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CEP13809.1 - 2e-10 40.0 13.5 2e-10 40.0 9.4 1.7 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family C1_3 PF07649.7 CEP13810.1 - 0.052 13.5 7.7 0.11 12.6 0.9 3.3 3 0 0 3 3 3 0 C1-like domain DAHP_synth_1 PF00793.15 CEP13811.1 - 2.2e-94 315.1 0.0 2.6e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2124 PF09897.4 CEP13811.1 - 0.12 12.0 0.0 1.2 8.7 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2124) PHP PF02811.14 CEP13812.1 - 1.1e-14 54.6 0.3 3.4e-14 53.0 0.2 1.8 1 1 1 2 2 2 1 PHP domain DUF4062 PF13271.1 CEP13812.1 - 0.05 13.6 0.2 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) Glucosamine_iso PF01182.15 CEP13813.1 - 1.1e-13 51.3 0.0 1.2e-08 34.9 0.0 2.4 1 1 1 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Asn_synthase PF00733.16 CEP13814.1 - 1.4e-56 191.8 0.0 1.9e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CEP13814.1 - 8.6e-41 138.5 0.0 1.4e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CEP13814.1 - 1.4e-35 122.1 0.0 2.8e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CEP13814.1 - 5.6e-05 22.0 0.0 0.31 9.7 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 CEP13814.1 - 0.092 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Aluminium induced protein DEAD PF00270.24 CEP13816.1 - 1.2e-39 135.5 0.0 7.7e-38 129.6 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP13816.1 - 4.4e-26 90.5 0.0 1.4e-25 88.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP13816.1 - 0.0024 17.7 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CEP13816.1 - 0.0096 14.3 0.0 4.5 5.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) CMS1 PF14617.1 CEP13816.1 - 0.15 11.1 0.1 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Tyr_Deacylase PF02580.11 CEP13817.1 - 3.6e-50 169.7 0.1 4e-50 169.5 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Rep_fac-A_C PF08646.5 CEP13817.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-CCHC PF00098.18 CEP13818.1 - 0.0027 17.5 1.2 0.0027 17.5 0.8 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CEP13818.1 - 0.38 10.4 5.4 0.7 9.6 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF2404 PF10296.4 CEP13819.1 - 8.3e-30 102.7 0.0 1.7e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) MRG PF05712.8 CEP13820.1 - 1.4e-53 180.6 3.9 2e-53 180.1 2.7 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 CEP13820.1 - 1.7e-12 46.8 1.1 3.8e-12 45.7 0.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CEP13820.1 - 0.49 10.1 6.7 0.21 11.3 2.5 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain ADH_zinc_N PF00107.21 CEP13821.1 - 1.3e-30 105.5 0.3 2.4e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP13821.1 - 3.6e-15 56.9 0.1 1.4e-14 55.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP13821.1 - 3.2e-11 42.9 0.1 4.1e-10 39.3 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 CEP13821.1 - 0.0023 17.9 0.2 0.005 16.8 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding Ribosomal_S8e PF01201.17 CEP13821.1 - 0.0036 17.4 0.2 0.0083 16.2 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e Arg_repressor_C PF02863.13 CEP13821.1 - 0.062 12.7 1.4 1.2 8.6 0.1 2.6 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Pribosyltran PF00156.22 CEP13822.1 - 6.4e-16 58.2 0.7 1.6e-15 56.9 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain SpoVAE PF14097.1 CEP13822.1 - 0.012 15.0 0.9 0.017 14.5 0.6 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AE1 CDP-OH_P_transf PF01066.16 CEP13823.1 - 3.9e-17 62.4 14.8 1.5e-16 60.5 10.2 2.0 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF1656 PF07869.7 CEP13823.1 - 0.043 13.6 1.4 2.1 8.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) DUF423 PF04241.10 CEP13823.1 - 0.96 9.4 3.7 2.9 7.8 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF423) HSF_DNA-bind PF00447.12 CEP13824.1 - 2e-37 127.5 1.4 2e-37 127.5 1.0 3.3 4 0 0 4 4 4 1 HSF-type DNA-binding SprA-related PF12118.3 CEP13824.1 - 0.0047 16.3 19.8 0.0047 16.3 13.7 3.4 2 1 1 3 3 3 1 SprA-related family Acyltransferase PF01553.16 CEP13825.1 - 9.7e-21 73.5 0.0 1.9e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase PX PF00787.19 CEP13827.1 - 6.8e-11 41.9 1.3 1.6e-10 40.7 0.9 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 CEP13827.1 - 0.0007 19.2 0.0 0.0036 16.9 0.0 2.3 2 0 0 2 2 2 1 PB1 domain Dynactin_p62 PF05502.8 CEP13828.1 - 4.1e-96 322.6 20.8 4.4e-54 184.0 11.6 2.4 1 1 1 2 2 2 2 Dynactin p62 family SET PF00856.23 CEP13829.1 - 1.8e-08 34.8 0.1 1.2e-05 25.6 0.0 2.9 3 0 0 3 3 3 2 SET domain CAF1 PF04857.15 CEP13830.1 - 1.7e-67 227.5 0.0 3e-67 226.7 0.0 1.4 1 1 0 1 1 1 1 CAF1 family ribonuclease Ldh_1_C PF02866.13 CEP13831.1 - 1.2e-44 152.0 0.0 2.2e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CEP13831.1 - 1.5e-44 151.2 0.1 2.4e-44 150.5 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CEP13831.1 - 8.1e-05 21.4 0.0 0.00023 19.9 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CEP13831.1 - 0.0019 18.0 1.3 0.0034 17.3 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.11 CEP13831.1 - 0.15 11.3 1.6 19 4.5 0.1 3.1 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Glyco_transf_20 PF00982.16 CEP13832.1 - 8.1e-155 515.8 0.0 1.2e-154 515.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEP13832.1 - 7.2e-57 192.0 0.0 1.1e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CEP13832.1 - 1.6e-05 24.6 0.2 0.13 11.7 0.1 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 CEP13832.1 - 0.041 14.0 0.0 0.93 9.6 0.0 2.8 2 1 1 3 3 3 0 Glycosyl transferases group 1 Polyhedrin PF00738.13 CEP13832.1 - 0.052 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Polyhedrin HTH_25 PF13413.1 CEP13832.1 - 0.14 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.20 CEP13833.1 - 2.7e-70 236.4 0.7 1.1e-68 231.1 0.5 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13833.1 - 4.3e-40 137.4 0.1 5.3e-39 133.8 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP13833.1 - 6.9e-06 25.2 0.0 2.7e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP13833.1 - 2e-05 23.7 0.9 4.5e-05 22.6 0.6 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP13833.1 - 0.00019 21.2 0.2 0.0012 18.6 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CEP13833.1 - 0.0004 19.8 0.9 0.00097 18.5 0.6 1.6 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 CEP13833.1 - 0.033 13.5 0.4 0.098 11.9 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CEP13833.1 - 0.034 13.7 0.1 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 CEP13833.1 - 0.13 11.4 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase CMD PF02627.15 CEP13834.1 - 0.00016 21.4 0.0 0.00067 19.4 0.0 2.0 2 1 1 3 3 3 1 Carboxymuconolactone decarboxylase family Fib_alpha PF08702.5 CEP13834.1 - 0.2 11.8 1.1 0.46 10.5 0.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RPE65 PF03055.10 CEP13835.1 - 2.3e-78 263.9 0.0 2.9e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Rhomboid PF01694.17 CEP13836.1 - 3.9e-05 23.6 1.4 0.00012 22.0 0.3 2.3 2 1 0 2 2 2 1 Rhomboid family KH_1 PF00013.24 CEP13837.1 - 2.8e-42 142.1 10.9 1.3e-16 59.9 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CEP13837.1 - 4.9e-30 102.6 13.4 6.1e-11 41.7 1.4 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CEP13837.1 - 4.4e-11 42.1 5.5 0.017 14.6 0.0 3.7 3 1 1 4 4 4 3 KH domain KH_4 PF13083.1 CEP13837.1 - 7.4e-10 38.3 1.2 0.041 13.5 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CEP13837.1 - 0.0038 16.9 5.2 0.3 10.8 0.1 3.5 3 0 0 3 3 3 1 NusA-like KH domain BAF1_ABF1 PF04684.8 CEP13837.1 - 0.011 14.5 7.0 0.02 13.7 4.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Abi PF02517.11 CEP13839.1 - 4.4e-16 58.7 11.1 1.1e-15 57.5 7.7 2.0 1 1 0 1 1 1 1 CAAX protease self-immunity Rad10 PF03834.9 CEP13840.1 - 2.5e-25 87.9 0.7 5e-25 86.9 0.5 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 CEP13840.1 - 5e-08 33.0 0.0 9.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 CEP13840.1 - 0.029 14.2 0.0 0.086 12.7 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pkinase PF00069.20 CEP13841.1 - 7.8e-63 212.0 0.0 2.7e-62 210.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13841.1 - 3.1e-31 108.3 0.0 5.1e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CEP13841.1 - 6.5e-08 32.9 0.0 2.6e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEP13841.1 - 5.2e-06 25.6 0.0 0.00017 20.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like PX PF00787.19 CEP13841.1 - 0.00026 20.7 0.9 0.00064 19.4 0.6 1.7 1 0 0 1 1 1 1 PX domain APH PF01636.18 CEP13841.1 - 0.0096 15.6 2.4 0.018 14.8 0.6 2.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Peptidase_S8 PF00082.17 CEP13842.1 - 1.2e-52 178.8 3.4 2e-52 178.1 2.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CEP13842.1 - 1.2e-14 54.6 0.4 2.2e-14 53.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ank_2 PF12796.2 CEP13843.1 - 2.6e-42 143.0 8.4 9.7e-12 45.0 0.1 4.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP13843.1 - 6.7e-20 71.0 5.5 2.5e-08 34.1 0.0 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 CEP13843.1 - 6.4e-19 66.7 7.0 0.0013 18.4 0.0 7.8 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 CEP13843.1 - 7e-16 57.8 2.6 2.2e-07 30.9 0.1 6.4 3 2 5 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP13843.1 - 1.6e-15 55.6 5.2 0.013 15.6 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat DDE_3 PF13358.1 CEP13844.1 - 3.4e-22 78.7 0.0 4.1e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP13844.1 - 0.00089 19.3 0.0 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain VIT PF08487.5 CEP13844.1 - 0.12 12.0 0.2 7.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Asparaginase_2 PF01112.13 CEP13845.1 - 1.6e-11 43.5 0.1 3.2e-09 35.9 0.0 2.0 2 0 0 2 2 2 2 Asparaginase Asparaginase_2 PF01112.13 CEP13846.1 - 9.5e-23 80.4 0.0 1.1e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Asparaginase AMP-binding PF00501.23 CEP13847.1 - 2e-58 197.7 0.0 4e-30 104.5 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CEP13847.1 - 2.6e-12 47.4 0.0 4.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Asp PF00026.18 CEP13848.1 - 3.7e-59 200.5 4.7 5.4e-58 196.7 3.3 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP13848.1 - 3.2e-07 30.4 0.2 4.8e-06 26.6 0.1 2.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal zf-C2H2 PF00096.21 CEP13848.1 - 7.7e-06 25.9 18.0 0.00057 20.0 3.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP13848.1 - 0.0014 18.8 4.3 0.0014 18.8 3.0 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CEP13848.1 - 0.0041 17.2 0.8 0.019 15.1 0.5 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CEP13848.1 - 0.0085 16.3 2.5 0.0085 16.3 1.8 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger Asp_protease_2 PF13650.1 CEP13848.1 - 0.12 12.8 0.6 3.2 8.3 0.0 3.1 2 1 1 3 3 3 0 Aspartyl protease zf-met PF12874.2 CEP13848.1 - 0.71 10.1 5.9 0.65 10.2 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ILVD_EDD PF00920.16 CEP13849.1 - 2.5e-210 699.3 1.4 2.9e-210 699.1 1.0 1.0 1 0 0 1 1 1 1 Dehydratase family Ras PF00071.17 CEP13850.1 - 9.7e-19 67.3 0.0 1e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP13850.1 - 4.5e-07 30.3 0.0 8e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP13850.1 - 0.00069 18.8 0.0 0.0008 18.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF106 PF01956.11 CEP13851.1 - 0.048 13.1 1.0 0.11 12.0 0.1 1.9 1 1 1 2 2 2 0 Integral membrane protein DUF106 MBOAT PF03062.14 CEP13852.1 - 2.9e-36 125.2 12.3 2.9e-36 125.2 8.5 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PsaL PF02605.10 CEP13852.1 - 0.026 14.0 0.9 0.22 11.0 0.0 2.6 3 0 0 3 3 3 0 Photosystem I reaction centre subunit XI DUF3329 PF11808.3 CEP13852.1 - 9.9 6.3 9.4 5.6 7.1 0.3 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3329) SRF-TF PF00319.13 CEP13853.1 - 1e-18 66.2 0.8 2e-18 65.3 0.2 1.7 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Med3 PF11593.3 CEP13853.1 - 0.0066 15.7 4.0 0.0085 15.3 2.8 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.14 CEP13853.1 - 0.016 15.6 4.2 0.026 14.9 2.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TFIIA PF03153.8 CEP13853.1 - 0.16 11.8 8.4 0.18 11.6 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HbrB PF08539.6 CEP13854.1 - 3.3e-32 111.5 0.2 1.1e-31 109.8 0.0 2.0 2 0 0 2 2 2 1 HbrB-like Zn_clus PF00172.13 CEP13854.1 - 0.65 9.9 5.8 1.3 8.9 4.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_3 PF13358.1 CEP13855.1 - 4.9e-22 78.2 0.1 8.2e-22 77.5 0.1 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP13855.1 - 3.9e-10 39.8 0.0 6.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP13855.1 - 4.7e-07 29.6 0.1 9.3e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP13855.1 - 2.7e-06 28.0 0.0 6.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 CEP13855.1 - 0.00013 21.4 0.1 0.00033 20.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 CEP13855.1 - 0.00088 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_IS630 PF01710.11 CEP13855.1 - 0.00092 18.8 1.1 0.0031 17.1 0.7 1.9 2 1 0 2 2 2 1 Transposase rve PF00665.21 CEP13855.1 - 0.0063 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_ISL3 PF13542.1 CEP13855.1 - 0.022 13.9 0.1 0.045 12.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 PAX PF00292.13 CEP13855.1 - 0.048 13.3 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Ndr PF03096.9 CEP13855.1 - 0.076 11.4 0.1 0.11 10.8 0.1 1.2 1 0 0 1 1 1 0 Ndr family Pkinase PF00069.20 CEP13857.1 - 2.2e-48 164.7 0.0 4.5e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13857.1 - 2.1e-41 141.7 0.0 3.5e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP13857.1 - 5.6e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP13857.1 - 0.011 15.5 0.1 1.4 8.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CEP13857.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1206 PF06724.6 CEP13858.1 - 8.3e-15 54.3 23.5 2e-08 33.8 2.5 3.8 3 1 0 3 3 3 2 Domain of Unknown Function (DUF1206) DDE_3 PF13358.1 CEP13859.1 - 2e-24 86.0 0.0 5.3e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP13859.1 - 5.2e-06 26.5 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP13859.1 - 3.8e-05 23.1 0.0 8.4e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP13859.1 - 0.00028 20.8 0.0 0.00067 19.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP13859.1 - 0.0016 18.6 0.0 0.0046 17.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain rve PF00665.21 CEP13859.1 - 0.0069 16.4 0.0 0.031 14.3 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Terminase_5 PF06056.7 CEP13859.1 - 0.014 14.9 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_IS630 PF01710.11 CEP13859.1 - 0.031 13.9 0.1 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 Transposase LZ_Tnp_IS481 PF13011.1 CEP13859.1 - 0.06 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Fungal_trans PF04082.13 CEP13860.1 - 4.5e-39 133.8 1.9 9.5e-39 132.8 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Atg14 PF10186.4 CEP13861.1 - 4.6e-19 68.4 3.4 8e-19 67.6 2.4 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CEP13861.1 - 1.8e-06 27.2 1.6 3.5e-06 26.2 1.1 1.5 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3552 PF12072.3 CEP13861.1 - 0.0042 16.3 5.9 0.0087 15.2 4.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) BCAS2 PF05700.6 CEP13861.1 - 0.023 14.1 6.8 0.056 12.9 4.7 1.6 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Homoserine_dh PF00742.14 CEP13862.1 - 1.6e-46 158.2 0.0 2.6e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CEP13862.1 - 4.2e-16 59.3 0.0 7.8e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CEP13862.1 - 0.00043 20.5 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CEP13862.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ras PF00071.17 CEP13863.1 - 1.1e-54 184.1 0.0 1.3e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP13863.1 - 3.5e-17 62.9 0.0 5.3e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP13863.1 - 9e-09 34.7 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 CEP13863.1 - 7.8e-05 21.9 0.1 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 CEP13863.1 - 0.002 17.3 0.0 0.0026 16.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEP13863.1 - 0.0045 16.9 0.0 0.0061 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CEP13863.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CEP13863.1 - 0.014 15.0 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF1397 PF07165.6 CEP13863.1 - 0.034 13.3 0.6 0.2 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) ABC_tran PF00005.22 CEP13863.1 - 0.037 14.3 0.0 0.068 13.4 0.0 1.3 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 CEP13863.1 - 0.054 12.1 0.0 0.066 11.8 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit RRM_1 PF00076.17 CEP13864.1 - 9.2e-56 185.3 0.2 2.4e-19 68.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP13864.1 - 2.5e-41 139.4 0.3 2.9e-14 52.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP13864.1 - 1.6e-29 101.5 0.1 5.4e-09 35.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP13864.1 - 0.00042 20.0 0.0 0.45 10.3 0.0 2.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 CEP13864.1 - 0.0066 15.9 0.0 3.9 7.0 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease B OB domain Limkain-b1 PF11608.3 CEP13864.1 - 0.025 14.3 0.1 0.51 10.1 0.0 2.8 3 1 0 3 3 3 0 Limkain b1 Big_3_3 PF13750.1 CEP13865.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) HIGH_NTase1 PF05636.6 CEP13866.1 - 0.00045 19.3 1.5 0.0019 17.3 0.1 2.0 2 0 0 2 2 2 1 HIGH Nucleotidyl Transferase GATA PF00320.22 CEP13867.1 - 2.6e-30 103.4 15.6 9e-16 56.9 2.3 2.7 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 CEP13867.1 - 7.2e-11 41.4 0.6 2.9e-10 39.5 0.5 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 CEP13867.1 - 0.008 15.4 4.5 0.085 12.1 0.1 2.9 2 1 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 CEP13867.1 - 0.019 14.7 9.2 0.39 10.5 4.1 3.6 2 1 2 4 4 4 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CEP13867.1 - 0.038 13.9 0.5 4 7.4 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 CEP13867.1 - 0.43 10.2 2.9 9.2 5.9 0.3 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DUF2406 PF10295.4 CEP13868.1 - 0.018 15.5 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) Dam PF05869.6 CEP13870.1 - 0.00022 20.7 0.2 0.00039 19.8 0.2 1.3 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) PRK PF00485.13 CEP13871.1 - 2.4e-28 99.0 0.0 3.1e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CEP13871.1 - 0.00021 21.5 0.1 0.00048 20.4 0.0 1.6 1 1 1 2 2 2 1 AAA domain MobB PF03205.9 CEP13871.1 - 0.063 12.9 0.0 0.9 9.2 0.0 2.6 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CEP13871.1 - 0.11 13.2 0.2 0.21 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain Lambda_CIII PF02061.11 CEP13871.1 - 0.36 10.8 1.5 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Lambda Phage CIII RRM_1 PF00076.17 CEP13872.1 - 8.2e-19 67.0 0.0 1.4e-13 50.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP13872.1 - 2.5e-10 40.1 0.0 1.1e-07 31.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP13872.1 - 0.12 12.2 0.0 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4175 PF13779.1 CEP13872.1 - 3.2 5.3 18.2 4.3 4.9 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SNF2_N PF00176.18 CEP13873.1 - 1.3e-74 250.7 0.3 2e-74 250.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP13873.1 - 1.5e-16 60.0 0.0 7.8e-16 57.7 0.0 2.3 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CEP13873.1 - 2.6e-10 39.9 5.4 6.3e-10 38.7 3.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP13873.1 - 3.5e-09 36.5 7.2 3.5e-09 36.5 5.0 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP13873.1 - 8.7e-09 34.9 4.7 2.2e-08 33.6 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP13873.1 - 1.4e-08 34.2 7.7 3e-08 33.1 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CEP13873.1 - 3.7e-07 29.7 0.0 1.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 CEP13873.1 - 4e-06 26.5 11.9 7.8e-06 25.6 5.1 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CEP13873.1 - 4.5e-06 26.2 6.3 8.9e-06 25.3 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CEP13873.1 - 5.4e-06 26.0 3.4 1.5e-05 24.5 2.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 CEP13873.1 - 0.0028 17.1 2.9 0.0057 16.1 2.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 CEP13873.1 - 0.0066 16.2 1.8 0.013 15.2 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CEP13873.1 - 0.02 14.4 5.5 0.045 13.3 3.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CEP13873.1 - 0.025 14.3 3.3 0.065 13.0 2.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CEP13873.1 - 0.038 14.0 2.5 0.095 12.8 1.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 CEP13873.1 - 0.057 12.9 2.3 0.15 11.6 1.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.6 CEP13873.1 - 0.095 12.4 0.4 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) SR-25 PF10500.4 CEP13873.1 - 3.7 6.9 10.5 0.065 12.7 2.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-PARP PF00645.13 CEP13874.1 - 1.9e-12 47.2 1.4 2.8e-12 46.6 0.1 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF605 PF04652.11 CEP13874.1 - 2.1 7.6 27.5 2.3 7.4 19.1 1.0 1 0 0 1 1 1 0 Vta1 like HTH_40 PF14493.1 CEP13874.1 - 2.3 8.4 6.4 13 6.0 4.5 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain Herpes_UL32 PF06070.6 CEP13874.1 - 3.9 5.8 29.2 4.5 5.6 20.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF572 PF04502.8 CEP13874.1 - 5.2 6.1 35.2 7.4 5.6 24.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Beta-lactamase PF00144.19 CEP13875.1 - 5.1e-40 137.5 0.6 4.3e-39 134.4 0.4 1.9 1 1 0 1 1 1 1 Beta-lactamase Baculo_PEP_C PF04513.7 CEP13876.1 - 0.00074 19.3 1.2 0.00084 19.1 0.8 1.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus MOR2-PAG1_N PF14222.1 CEP13876.1 - 0.025 13.3 0.4 0.027 13.1 0.3 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Effector_1 PF04518.7 CEP13876.1 - 0.029 13.3 0.4 0.031 13.2 0.3 1.1 1 0 0 1 1 1 0 Effector from type III secretion system LTXXQ PF07813.7 CEP13876.1 - 0.042 14.2 0.0 0.05 14.0 0.0 1.1 1 0 0 1 1 1 0 LTXXQ motif family protein Mating_N PF12731.2 CEP13876.1 - 0.13 12.1 0.5 0.99 9.3 0.4 1.9 1 1 0 1 1 1 0 Mating-type protein beta 1 Helicase_C_2 PF13307.1 CEP13877.1 - 2.8e-53 180.2 0.0 8.4e-53 178.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 CEP13877.1 - 1.7e-49 167.5 0.1 2.9e-49 166.8 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 CEP13877.1 - 0.00043 20.1 0.6 0.24 11.2 0.2 3.3 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit E1-E2_ATPase PF00122.15 CEP13878.1 - 1.3e-28 99.6 0.0 7.8e-28 97.0 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CEP13878.1 - 2.8e-18 66.7 0.0 5.2e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP13878.1 - 2.1e-15 57.7 0.0 2.2e-14 54.4 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP13878.1 - 0.0011 18.3 0.0 0.0011 18.3 0.0 3.0 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP13878.1 - 0.0016 18.0 0.2 0.028 13.9 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP13878.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Glyco_hydro_16 PF00722.16 CEP13881.1 - 1.3e-22 80.0 3.3 3.9e-22 78.4 2.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.6 CEP13881.1 - 0.012 15.5 2.9 0.13 12.1 2.0 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) DUF2854 PF11016.3 CEP13881.1 - 0.029 13.8 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) L-fibroin PF05849.6 CEP13882.1 - 0.35 10.1 4.2 0.62 9.3 0.3 2.3 2 0 0 2 2 2 0 Fibroin light chain (L-fibroin) Ribosomal_L44 PF00935.14 CEP13883.1 - 5.6e-36 122.3 9.7 8.4e-36 121.8 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 CEP13883.1 - 2.7 8.3 8.3 2.6 8.3 0.9 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 Ldh_1_N PF00056.18 CEP13884.1 - 2.8e-33 114.7 1.3 4.3e-33 114.1 0.6 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CEP13884.1 - 2.2e-27 95.8 0.0 3.5e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Shikimate_DH PF01488.15 CEP13884.1 - 0.0013 18.8 0.2 0.0023 18.0 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 CEP13884.1 - 0.0029 17.0 0.7 0.014 14.7 0.5 2.1 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 CEP13884.1 - 0.015 14.7 0.6 0.064 12.7 0.4 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 CEP13884.1 - 0.016 15.0 0.1 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 CEP13884.1 - 0.017 14.8 0.3 0.035 13.7 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CEP13884.1 - 0.029 14.7 0.1 0.071 13.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 CEP13884.1 - 0.062 13.7 1.5 0.13 12.7 0.4 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAA_hydrolase PF01557.13 CEP13884.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family NAD_binding_8 PF13450.1 CEP13884.1 - 0.082 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEP13884.1 - 0.21 10.4 1.5 0.3 9.9 0.7 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Toxin_trans PF07952.7 CEP13885.1 - 0.12 11.3 0.1 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain tRNA-synt_1 PF00133.17 CEP13886.1 - 2.2e-64 217.5 0.0 2.8e-22 78.4 0.3 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 CEP13886.1 - 3.8e-55 186.0 0.0 5.9e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 CEP13886.1 - 2e-32 112.3 0.1 9.2e-25 87.1 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CEP13886.1 - 6.3e-19 68.2 0.0 1.3e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 CEP13886.1 - 0.016 14.0 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CEP13886.1 - 0.035 13.2 0.0 0.35 9.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GCN5L1 PF06320.8 CEP13886.1 - 0.1 12.4 0.7 0.26 11.1 0.5 1.6 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) MoCF_biosynth PF00994.19 CEP13887.1 - 9e-62 206.7 0.5 7.8e-30 103.1 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 CEP13887.1 - 1.3e-35 122.1 0.5 2.3e-35 121.3 0.3 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 CEP13887.1 - 1.5e-12 47.2 0.0 5.2e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Radical_SAM PF04055.16 CEP13887.1 - 0.15 12.2 0.0 14 5.8 0.0 2.7 3 0 0 3 3 3 0 Radical SAM superfamily Polyketide_cyc2 PF10604.4 CEP13888.1 - 0.0024 18.0 0.1 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Nol1_Nop2_Fmu PF01189.12 CEP13889.1 - 6.7e-22 78.1 0.0 1.9e-13 50.4 0.0 2.3 1 1 1 2 2 2 2 NOL1/NOP2/sun family Methyltransf_18 PF12847.2 CEP13889.1 - 1e-05 26.0 0.0 3.5e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP13889.1 - 0.00019 21.0 0.2 0.0071 15.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP13889.1 - 0.00021 21.5 0.1 0.00068 19.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP13889.1 - 0.0013 18.7 0.0 0.0054 16.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEP13889.1 - 0.041 13.4 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 CEP13889.1 - 0.12 12.3 0.3 0.33 10.9 0.2 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 CEP13889.1 - 0.13 11.5 0.1 0.43 9.9 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Acetyltransf_1 PF00583.19 CEP13890.1 - 1.6e-10 40.8 0.0 2.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP13890.1 - 5.5e-07 29.6 0.0 7.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP13890.1 - 0.00056 20.0 0.0 0.0011 19.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 CEP13890.1 - 0.00077 20.0 0.1 0.0035 17.8 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP13890.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEP13890.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 CEP13890.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF4625 PF15418.1 CEP13893.1 - 0.00033 20.7 0.0 0.00047 20.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) SQS_PSY PF00494.14 CEP13894.1 - 3.1e-40 138.1 0.0 4.4e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF1673 PF07895.6 CEP13894.1 - 4.2 6.8 6.3 2.4 7.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) ArfGap PF01412.13 CEP13895.1 - 0.00024 20.8 0.3 0.00058 19.6 0.0 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf LNP1 PF15419.1 CEP13895.1 - 0.0034 17.4 0.0 0.0039 17.2 0.0 1.1 1 0 0 1 1 1 1 Leukemia NUP98 fusion partner 1 AAA PF00004.24 CEP13896.1 - 4.1e-18 65.8 0.0 9.5e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CEP13896.1 - 1.4e-15 57.3 0.2 1.2e-13 51.0 0.0 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CEP13896.1 - 1.7e-12 47.1 0.9 3.6e-12 46.0 0.6 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CEP13896.1 - 7.3e-07 29.3 0.2 6.5e-05 23.0 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 CEP13896.1 - 2.2e-06 27.3 0.0 4.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CEP13896.1 - 4.8e-06 26.3 0.0 9e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 CEP13896.1 - 1.5e-05 23.8 0.1 0.065 11.9 0.0 2.4 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CEP13896.1 - 4.2e-05 23.4 0.0 9.9e-05 22.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CEP13896.1 - 6.8e-05 22.1 0.0 0.019 14.0 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CEP13896.1 - 0.00016 21.4 0.0 0.00056 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEP13896.1 - 0.00021 20.4 0.0 0.00052 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEP13896.1 - 0.00024 21.1 0.0 0.002 18.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 CEP13896.1 - 0.0012 19.0 0.3 0.028 14.5 0.0 2.5 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.10 CEP13896.1 - 0.0019 18.0 0.0 0.0068 16.2 0.0 1.9 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 CEP13896.1 - 0.0038 16.2 0.0 0.009 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CEP13896.1 - 0.0054 17.5 0.0 0.013 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CEP13896.1 - 0.0056 16.2 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CEP13896.1 - 0.011 14.7 0.0 0.028 13.4 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CEP13896.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 CEP13896.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 CEP13896.1 - 0.015 14.8 2.5 0.017 14.7 0.4 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CEP13896.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 CEP13896.1 - 0.031 13.7 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 CEP13896.1 - 0.034 13.6 0.3 0.73 9.2 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_3 PF07726.6 CEP13896.1 - 0.035 13.6 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CEP13896.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 CEP13896.1 - 0.041 12.6 0.0 0.46 9.2 0.0 2.0 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_25 PF13481.1 CEP13896.1 - 0.051 12.9 0.1 0.18 11.1 0.0 1.8 1 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CEP13896.1 - 0.055 13.7 0.1 0.072 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEP13896.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CEP13896.1 - 0.11 12.0 0.6 1.2 8.5 0.0 2.5 2 1 0 3 3 3 0 DEAD/DEAH box helicase HMG-CoA_red PF00368.13 CEP13898.1 - 1.2e-162 540.7 6.1 1.2e-162 540.7 4.2 2.0 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 CEP13898.1 - 8.6e-16 57.7 3.8 2.4e-15 56.3 2.6 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CEP13898.1 - 1.5e-08 33.0 7.7 2.7e-08 32.2 5.3 1.3 1 0 0 1 1 1 1 Patched family HPIH PF13323.1 CEP13898.1 - 0.024 14.3 0.1 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain with HPIH motif PHD PF00628.24 CEP13899.1 - 1.6e-17 62.9 25.0 4.2e-10 39.1 6.8 3.1 3 1 1 4 4 4 2 PHD-finger C1_1 PF00130.17 CEP13899.1 - 0.0086 15.7 17.0 0.041 13.6 1.1 3.1 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 CEP13899.1 - 0.031 14.3 15.1 1.3 9.2 5.6 2.9 2 1 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_M15_3 PF08291.6 CEP13899.1 - 0.37 10.6 3.8 1.2 9.0 0.1 3.0 3 1 0 3 3 3 0 Peptidase M15 Prok-RING_1 PF14446.1 CEP13899.1 - 8.3 6.2 20.9 0.32 10.7 0.6 3.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 BRCT PF00533.21 CEP13900.1 - 2.6e-13 49.9 0.0 5.6e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CEP13900.1 - 0.00036 20.3 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF937 PF06078.6 CEP13900.1 - 0.33 11.1 1.9 0.44 10.7 0.4 1.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF937) SPT16 PF08644.6 CEP13901.1 - 2.7e-53 179.8 2.7 3.7e-53 179.4 0.0 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CEP13901.1 - 1.2e-37 128.9 0.2 2.6e-37 127.8 0.2 1.6 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CEP13901.1 - 2.2e-28 99.2 0.0 3.8e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CEP13901.1 - 2.2e-22 78.8 0.0 6.8e-22 77.2 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like WD40 PF00400.27 CEP13902.1 - 0.083 12.8 2.3 2.6 8.0 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Retrotrans_gag PF03732.12 CEP13905.1 - 0.00017 21.5 0.0 0.00043 20.2 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein AlaDh_PNT_N PF05222.10 CEP13905.1 - 0.029 14.3 0.4 0.077 12.9 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain KH_1 PF00013.24 CEP13906.1 - 3.4e-46 154.7 6.0 2.6e-16 58.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CEP13906.1 - 2e-34 116.6 12.8 4e-12 45.4 0.9 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CEP13906.1 - 9.2e-14 50.7 2.5 0.0019 17.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CEP13906.1 - 1.8e-09 37.0 4.8 0.00046 19.7 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CEP13906.1 - 0.0006 19.5 4.8 0.8 9.5 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain BMC PF00936.14 CEP13906.1 - 0.033 13.8 0.1 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 BMC domain CDK2AP PF09806.4 CEP13906.1 - 3.8 7.7 8.4 4 7.6 0.7 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DpnD-PcfM PF14207.1 CEP13907.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 DpnD/PcfM-like protein Fz PF01392.17 CEP13908.1 - 1.2e-05 25.6 1.6 1.2e-05 25.6 1.1 1.8 2 0 0 2 2 2 1 Fz domain 7tm_2 PF00002.19 CEP13908.1 - 3.3e-05 23.1 12.3 5.6e-05 22.3 8.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ribosomal_S4 PF00163.14 CEP13909.1 - 1.1e-26 93.0 1.3 2e-26 92.2 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CEP13909.1 - 3.1e-13 48.9 1.4 3.1e-13 48.9 1.0 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 CEP13910.1 - 9.9e-43 143.9 3.6 9.9e-43 143.9 2.5 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e DUF1989 PF09347.5 CEP13910.1 - 0.0091 15.4 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) MIF4G PF02854.14 CEP13911.1 - 3.9e-29 101.5 2.2 6.3e-29 100.8 0.1 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CEP13911.1 - 2.9e-26 91.4 0.1 6e-26 90.3 0.1 1.6 1 0 0 1 1 1 1 MA3 domain DUF1456 PF07308.8 CEP13911.1 - 0.064 13.2 0.2 25 4.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Tho2 PF11262.3 CEP13912.1 - 2.6e-60 203.9 4.4 2.6e-60 203.9 3.0 1.7 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CEP13912.1 - 9.7e-16 57.3 0.0 9.6e-15 54.1 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Homeobox PF00046.24 CEP13913.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Homeobox domain Homeobox_KN PF05920.6 CEP13913.1 - 0.092 12.4 0.2 0.64 9.7 0.0 2.2 1 1 1 2 2 2 0 Homeobox KN domain DUF3993 PF13158.1 CEP13914.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Helitron_like_N PF14214.1 CEP13915.1 - 0.0011 18.7 0.1 0.0018 18.0 0.1 1.5 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF2088 PF09861.4 CEP13917.1 - 0.0039 16.2 0.0 0.01 14.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2088) RVP_2 PF08284.6 CEP13918.1 - 0.00059 19.7 0.0 0.00091 19.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEP13918.1 - 0.0017 18.7 0.1 0.0053 17.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.18 CEP13918.1 - 0.0022 17.8 0.8 0.0045 16.8 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.15 CEP13918.1 - 0.0058 16.5 0.4 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.22 CEP13919.1 - 3.4e-07 29.8 0.1 0.0025 17.2 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 CEP13920.1 - 0.0014 18.0 0.7 0.0033 16.7 0.5 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger PIF1 PF05970.9 CEP13922.1 - 1.4e-11 43.9 0.0 2.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP13922.1 - 5.1e-06 26.2 0.0 8.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CEP13922.1 - 3e-05 23.6 0.0 0.0034 16.9 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 CEP13922.1 - 0.012 15.4 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CEP13922.1 - 0.02 15.6 0.1 0.05 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.9 CEP13922.1 - 0.021 12.6 0.1 0.27 8.9 0.0 2.0 2 0 0 2 2 2 0 Helicase AAA_22 PF13401.1 CEP13922.1 - 0.035 14.2 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEP13922.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 CEP13922.1 - 0.077 12.7 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 CEP13922.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF1967 PF09269.6 CEP13922.1 - 0.095 12.3 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) PhoH PF02562.11 CEP13922.1 - 0.12 11.6 0.2 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 CEP13922.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 CEP13923.1 - 2.2e-16 59.7 0.1 2.3e-16 59.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP13923.1 - 2e-09 37.3 0.0 2.2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CEP13923.1 - 8.4e-05 22.4 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CEP13923.1 - 0.0005 19.3 0.0 0.00068 18.9 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.1 CEP13923.1 - 0.00082 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CEP13923.1 - 0.0009 18.8 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 CEP13923.1 - 0.0012 19.1 0.0 0.0027 18.0 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 CEP13923.1 - 0.0022 18.1 0.1 0.0039 17.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP13923.1 - 0.012 16.4 0.1 0.014 16.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP13923.1 - 0.015 14.9 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 CEP13923.1 - 0.016 14.2 0.2 0.036 13.0 0.1 1.5 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CEP13923.1 - 0.025 14.2 0.9 0.097 12.3 0.7 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 CEP13923.1 - 0.044 13.2 0.1 0.064 12.6 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain DUF815 PF05673.8 CEP13923.1 - 0.047 12.6 0.3 0.096 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 CEP13923.1 - 0.052 13.5 0.1 0.13 12.2 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 CEP13923.1 - 0.053 12.7 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 CEP13923.1 - 0.071 13.3 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1967 PF09269.6 CEP13923.1 - 0.077 12.6 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1967) RNA_helicase PF00910.17 CEP13923.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 CEP13923.1 - 0.093 12.2 0.3 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain GBP PF02263.14 CEP13923.1 - 0.15 11.1 0.5 0.6 9.1 0.1 1.9 1 1 0 2 2 2 0 Guanylate-binding protein, N-terminal domain RVT_1 PF00078.22 CEP13924.1 - 0.0004 19.8 0.0 0.00044 19.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP13925.1 - 1.1e-20 73.8 0.1 2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CBS PF00571.23 CEP13928.1 - 6.4e-20 70.6 0.1 9.5e-05 22.1 0.0 4.4 4 0 0 4 4 4 4 CBS domain Chitin_synth_1 PF01644.12 CEP13929.1 - 2.5e-76 255.0 0.1 7.2e-76 253.5 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase DUF21 PF01595.15 CEP13929.1 - 9.2e-33 113.0 2.9 1.9e-32 112.0 1.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF21 Chitin_synth_1N PF08407.6 CEP13929.1 - 3.6e-28 97.0 0.7 1.1e-27 95.4 0.5 1.9 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEP13929.1 - 3.9e-24 84.9 0.5 8.1e-24 83.8 0.0 1.6 2 0 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 CEP13929.1 - 1.4e-08 34.8 0.0 3.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEP13929.1 - 2.6e-07 30.5 1.9 3.5e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 CBS PF00571.23 CEP13929.1 - 1.8e-06 27.6 0.0 0.037 13.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain Ribosomal_S27e PF01667.12 CEP13930.1 - 2.8e-30 103.5 3.5 3.4e-30 103.3 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CEP13930.1 - 0.0003 20.6 1.2 0.00035 20.3 0.8 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CEP13930.1 - 0.00085 18.5 2.5 0.0012 18.0 1.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 CEP13930.1 - 0.14 11.8 1.1 0.18 11.4 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.1 CEP13930.1 - 0.17 11.6 1.9 0.24 11.1 1.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.1 CEP13930.1 - 0.2 10.9 3.0 4.2 6.7 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CEP13930.1 - 0.24 11.1 2.6 9.3 6.0 1.8 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CEP13930.1 - 0.34 10.5 2.7 13 5.4 1.9 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2HC5 PF06221.8 CEP13930.1 - 0.4 10.4 4.4 0.98 9.2 3.1 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Tnp_zf-ribbon_2 PF13842.1 CEP13930.1 - 0.45 10.9 2.5 0.93 9.9 1.7 1.6 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RecR PF02132.10 CEP13930.1 - 1 8.8 3.8 2.6 7.5 0.6 2.2 2 0 0 2 2 2 0 RecR protein DDE_3 PF13358.1 CEP13931.1 - 4.1e-14 52.5 0.0 7.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP13931.1 - 3.6e-05 24.4 0.0 0.00017 22.3 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP13931.1 - 9.3e-05 22.5 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1 PF01527.15 CEP13931.1 - 0.0037 17.1 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 Transposase Terminase_5 PF06056.7 CEP13931.1 - 0.0049 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.1 CEP13931.1 - 0.012 15.2 1.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.1 CEP13931.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain PHO4 PF01384.15 CEP13932.1 - 1.1e-111 372.6 21.1 1.4e-111 372.3 14.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family Pkinase PF00069.20 CEP13934.1 - 5.3e-30 104.4 0.0 8.8e-30 103.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP13934.1 - 1.1e-08 34.5 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP13934.1 - 0.17 11.5 0.0 7.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3402 PF11882.3 CEP13935.1 - 2.2e-93 313.5 11.5 1.5e-92 310.8 8.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CEP13935.1 - 3.1e-17 62.3 16.3 3.1e-16 59.0 0.7 3.3 2 1 1 3 3 3 2 N1221-like protein CAF1A PF12253.3 CEP13936.1 - 9.1e-21 73.7 5.0 1.8e-20 72.7 3.5 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A DUF4218 PF13960.1 CEP13939.1 - 7.7e-06 25.3 0.5 1.7e-05 24.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) zf-ISL3 PF14690.1 CEP13939.1 - 0.0077 16.2 0.0 0.038 14.0 0.0 2.2 1 0 0 1 1 1 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF4340 PF14238.1 CEP13940.1 - 0.076 12.7 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) PGAP1 PF07819.8 CEP13944.1 - 1.4e-78 263.5 0.0 2e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CEP13944.1 - 2e-05 24.3 0.0 4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP13944.1 - 0.00088 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CEP13944.1 - 0.0042 16.3 0.4 0.014 14.6 0.3 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 CEP13944.1 - 0.0072 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 CEP13944.1 - 0.024 13.7 0.2 1.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CEP13944.1 - 0.038 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) COesterase PF00135.23 CEP13944.1 - 0.085 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family LCAT PF02450.10 CEP13944.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ribosomal_L28e PF01778.12 CEP13945.1 - 7.1e-36 123.1 6.3 9.4e-36 122.7 4.4 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Big_1 PF02369.11 CEP13945.1 - 0.059 13.2 0.3 0.096 12.6 0.2 1.4 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) Use1 PF09753.4 CEP13945.1 - 0.071 12.5 1.0 0.077 12.4 0.7 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 NUFIP1 PF10453.4 CEP13946.1 - 1.8e-12 46.5 10.3 1.8e-12 46.5 7.1 2.3 2 1 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 CEP13946.1 - 3.9e-05 23.2 3.7 7.2e-05 22.3 2.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1018 PF06252.7 CEP13946.1 - 0.61 10.6 4.6 11 6.5 0.7 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1018) Usp PF00582.21 CEP13947.1 - 0.052 13.7 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 Universal stress protein family Arrestin_N PF00339.24 CEP13948.1 - 5.7e-14 52.1 0.1 4.3e-12 46.0 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Ferritin PF00210.19 CEP13949.1 - 4.9e-12 45.8 0.1 3.2e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Ferritin-like domain SelR PF01641.13 CEP13949.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 SelR domain 2OG-FeII_Oxy_3 PF13640.1 CEP13950.1 - 1.1e-10 41.9 0.1 4.5e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CEP13950.1 - 0.00036 20.1 0.2 0.00065 19.2 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BTB_2 PF02214.17 CEP13951.1 - 0.0038 17.4 0.1 0.053 13.7 0.0 2.6 2 1 0 2 2 2 1 BTB/POZ domain TPT PF03151.11 CEP13952.1 - 9.7e-35 119.4 9.1 9.7e-35 119.4 6.3 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CEP13952.1 - 3.7e-14 52.3 18.7 4.4e-11 42.2 6.1 2.2 1 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 CEP13952.1 - 4.8e-10 39.5 6.2 4.8e-10 39.5 4.3 2.6 3 0 0 3 3 3 2 EamA-like transporter family Multi_Drug_Res PF00893.14 CEP13952.1 - 0.033 14.6 0.7 0.033 14.6 0.5 2.6 2 1 1 3 3 3 0 Small Multidrug Resistance protein Metalloenzyme PF01676.13 CEP13953.1 - 1.8e-80 269.9 0.1 2.1e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 CEP13953.1 - 1.7e-72 243.4 0.0 2.2e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 CEP13953.1 - 4.7e-07 29.4 0.0 8.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CEP13953.1 - 2.6e-05 23.5 0.0 0.0001 21.6 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.15 CEP13953.1 - 0.017 13.8 0.2 0.039 12.6 0.1 1.6 2 0 0 2 2 2 0 Alkaline phosphatase PglZ PF08665.7 CEP13953.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 PglZ domain Fungal_trans PF04082.13 CEP13954.1 - 1.1e-07 30.9 0.9 1.1e-07 30.9 0.6 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain SR-25 PF10500.4 CEP13954.1 - 5.7 6.3 13.9 0.19 11.1 1.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tom22 PF04281.8 CEP13955.1 - 6.4e-36 122.9 2.8 1.3e-35 121.9 2.0 1.5 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 BSMAP PF12280.3 CEP13955.1 - 0.16 11.8 0.4 0.23 11.3 0.0 1.5 2 0 0 2 2 2 0 Brain specific membrane anchored protein GvpG PF05120.7 CEP13955.1 - 2.3 8.1 6.3 0.52 10.1 1.1 2.2 2 1 0 2 2 2 0 Gas vesicle protein G Mre11_DNA_bind PF04152.9 CEP13956.1 - 4.6e-44 150.3 0.2 1e-43 149.2 0.1 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CEP13956.1 - 7.2e-21 74.5 2.4 1.2e-20 73.7 1.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP13956.1 - 4.9e-07 29.7 0.0 1.4e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Dehydrin PF00257.14 CEP13957.1 - 0.0097 16.2 0.3 0.017 15.4 0.2 1.3 1 0 0 1 1 1 1 Dehydrin MCPVI PF02993.9 CEP13957.1 - 0.097 12.8 2.9 0.12 12.4 2.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Fer4 PF00037.22 CEP13959.1 - 0.68 9.6 9.3 0.47 10.1 0.2 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Rad50_zn_hook PF04423.9 CEP13959.1 - 1.7 8.1 5.4 2.4 7.7 0.8 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Med17 PF10156.4 CEP13960.1 - 6.6e-42 143.3 7.4 8.6e-41 139.6 5.2 2.0 1 1 0 1 1 1 1 Subunit 17 of Mediator complex Glyco_transf_64 PF09258.5 CEP13961.1 - 9.5e-37 126.4 0.4 1.7e-36 125.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.15 CEP13961.1 - 4.7e-33 114.5 6.0 4.7e-33 114.5 4.2 3.2 3 1 0 3 3 3 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 CEP13961.1 - 5.1e-05 23.1 0.4 0.00012 21.9 0.3 1.7 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 CEP13961.1 - 0.00077 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative EamA PF00892.15 CEP13961.1 - 0.036 14.1 12.6 0.16 12.0 4.2 2.4 2 0 0 2 2 2 0 EamA-like transporter family B12D PF06522.6 CEP13963.1 - 9.2e-17 60.5 0.0 1.1e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PIF1 PF05970.9 CEP13965.1 - 8.4e-31 107.2 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP13965.1 - 7.6e-06 23.9 0.0 9.6e-06 23.6 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP13965.1 - 4.4e-05 23.5 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HTH_28 PF13518.1 CEP13966.1 - 1.4e-07 31.3 0.0 2.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP13966.1 - 4.2e-05 23.0 0.0 9.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP13966.1 - 7.1e-05 22.9 0.0 0.00011 22.3 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix PAX PF00292.13 CEP13966.1 - 0.027 14.1 0.1 0.031 13.9 0.1 1.1 1 0 0 1 1 1 0 'Paired box' domain TrmB PF01978.14 CEP13966.1 - 0.035 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB 7TMR-DISMED2 PF07696.6 CEP13966.1 - 0.036 13.5 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 HTH_32 PF13565.1 CEP13966.1 - 0.052 14.3 0.0 0.085 13.6 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Chromo PF00385.19 CEP13967.1 - 2.5e-09 36.6 0.2 4.4e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CEP13968.1 - 2.6e-14 53.3 0.0 9.8e-14 51.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 CEP13968.1 - 0.00025 20.4 0.3 0.00059 19.1 0.2 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger WD40 PF00400.27 CEP13972.1 - 1.7e-63 208.3 23.9 2.2e-11 43.1 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CEP13972.1 - 5.6e-06 26.1 0.2 3e-05 23.8 0.0 2.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CEP13972.1 - 0.00013 20.2 10.3 0.011 13.9 1.0 4.7 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CEP13972.1 - 0.0037 15.6 0.0 1.2 7.3 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain Aminotran_3 PF00202.16 CEP13973.1 - 5e-45 153.8 0.0 1.5e-25 89.7 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 CEP13973.1 - 4.2e-33 114.6 0.0 6.8e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain BATS PF06968.8 CEP13974.1 - 5.9e-28 96.5 0.1 1.5e-27 95.2 0.1 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CEP13974.1 - 1.5e-14 54.5 0.1 2.1e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily DUF1394 PF07159.7 CEP13975.1 - 8.5e-83 277.9 0.0 1e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.1 CEP13975.1 - 0.053 11.7 0.1 0.13 10.3 0.0 1.6 2 0 0 2 2 2 0 WASH complex subunit 7, N-terminal Ribosomal_L22 PF00237.14 CEP13976.1 - 3e-34 117.1 0.1 3.9e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L15e PF00827.12 CEP13977.1 - 7.3e-90 299.6 11.4 8.3e-90 299.4 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 zf-CCCH PF00642.19 CEP13981.1 - 3.7e-12 45.6 15.4 4.2e-07 29.5 1.7 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CEP13981.1 - 4.8e-05 23.1 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP13981.1 - 0.0011 18.5 0.1 0.0029 17.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ctr PF04145.10 CEP13982.1 - 1.8e-27 96.1 0.1 2.6e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Aminotran_1_2 PF00155.16 CEP13983.1 - 1.2e-29 103.4 0.0 1.2e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CEP13983.1 - 4.7e-09 35.3 0.0 6.3e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF3060 PF11259.3 CEP13984.1 - 0.19 11.4 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) SET PF00856.23 CEP13985.1 - 7.1e-08 32.9 0.0 1.9e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 SET domain DASH_Spc19 PF08287.6 CEP13988.1 - 0.048 13.2 0.2 0.056 13.0 0.1 1.1 1 0 0 1 1 1 0 Spc19 AT_hook PF02178.14 CEP13988.1 - 0.12 12.1 2.6 0.24 11.1 1.8 1.5 1 0 0 1 1 1 0 AT hook motif Big_3 PF07523.7 CEP13989.1 - 0.1 12.6 0.1 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) adh_short PF00106.20 CEP13991.1 - 5.4e-19 68.7 0.0 9.2e-19 67.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP13991.1 - 4.4e-13 49.5 0.0 6.8e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP13991.1 - 0.00012 21.7 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEP13991.1 - 0.0016 18.4 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CEP13991.1 - 0.0039 16.6 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CEP13991.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family zf-C2H2_4 PF13894.1 CEP13993.1 - 0.00024 21.2 0.2 0.00054 20.0 0.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP13993.1 - 0.0026 17.9 0.5 0.0026 17.9 0.4 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CEP13993.1 - 0.025 14.6 0.1 0.056 13.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CEP13993.1 - 0.053 13.2 0.1 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger zf-met PF12874.2 CEP13993.1 - 0.12 12.5 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Upf2 PF04050.9 CEP13993.1 - 0.54 10.0 10.8 1 9.1 7.5 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 NOA36 PF06524.7 CEP13993.1 - 1.4 8.0 6.0 1.9 7.6 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 CEP13995.1 - 0.017 13.1 2.0 0.019 13.0 1.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Nipped-B_C PF12830.2 CEP13995.1 - 0.025 14.2 0.6 0.033 13.8 0.4 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus UQ_con PF00179.21 CEP13995.1 - 0.037 13.4 0.8 0.093 12.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme Condensin2nSMC PF12422.3 CEP13995.1 - 0.09 12.5 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit SURF6 PF04935.7 CEP13995.1 - 0.29 10.3 4.5 0.4 9.9 3.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 Ins145_P3_rec PF08709.6 CEP13997.1 - 0.037 13.0 0.1 0.052 12.5 0.1 1.2 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Zn_Tnp_IS1595 PF12760.2 CEP13997.1 - 0.12 12.2 1.6 0.22 11.3 1.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.8 CEP13997.1 - 1.8 8.3 5.7 7.8 6.2 0.2 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Lzipper-MIP1 PF14389.1 CEP13998.1 - 0.003 17.6 0.2 0.0057 16.7 0.1 1.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 CEP13998.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-C4H2 PF10146.4 CEP13998.1 - 0.043 13.8 1.5 0.064 13.2 1.1 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4140 PF13600.1 CEP13998.1 - 0.22 11.9 4.9 0.09 13.2 0.8 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Transposase_21 PF02992.9 CEP13999.1 - 9.7e-06 24.8 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Sulfolobus_pRN PF05584.6 CEP13999.1 - 0.015 15.2 0.1 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein zf-CCHC PF00098.18 CEP14000.1 - 1.3e-05 24.9 10.1 0.012 15.4 3.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CEP14000.1 - 0.054 13.2 2.4 0.1 12.3 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Nucleoporin_N PF08801.6 CEP14001.1 - 2.9e-11 42.7 0.8 2.8e-09 36.2 0.1 3.5 2 1 0 2 2 2 1 Nup133 N terminal like Aa_trans PF01490.13 CEP14002.1 - 5.5e-16 58.0 28.3 5.5e-16 58.0 19.6 2.0 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CEP14002.1 - 7.7e-06 24.9 15.5 7.7e-06 24.9 10.8 1.9 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family SMK-1 PF04802.10 CEP14003.1 - 4.5e-55 186.1 3.3 2.8e-54 183.5 2.2 2.3 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.13 CEP14003.1 - 0.0036 17.3 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 RanBP1 domain Kei1 PF08552.6 CEP14003.1 - 8.8 5.9 8.3 30 4.2 5.7 1.9 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Kelch_4 PF13418.1 CEP14005.1 - 3.5e-28 97.1 6.1 1.6e-09 37.3 0.1 5.6 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP14005.1 - 5.7e-23 80.4 4.7 8.4e-07 28.9 0.1 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP14005.1 - 3.3e-22 77.6 4.6 2.8e-05 24.0 0.0 5.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 CEP14005.1 - 1.5e-21 75.2 5.2 0.00013 21.6 0.1 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 CEP14005.1 - 9.5e-21 73.0 6.9 0.0001 21.7 0.2 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 CEP14005.1 - 3.2e-19 68.4 4.6 0.00014 21.6 0.0 5.6 6 0 0 6 6 6 4 Kelch motif BTB PF00651.26 CEP14005.1 - 2.2e-12 46.9 0.0 5.5e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Zip PF02535.17 CEP14005.1 - 0.011 14.7 0.6 0.011 14.7 0.4 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Macoilin PF09726.4 CEP14005.1 - 0.26 9.5 3.3 0.35 9.0 2.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 CEP14006.1 - 2.3e-73 246.5 0.1 2.3e-73 246.5 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14006.1 - 1.2e-52 178.5 0.1 1.2e-52 178.5 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 CEP14006.1 - 2.7e-19 69.3 0.0 1.6e-18 66.8 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CEP14006.1 - 1.6e-08 33.8 0.1 1.4e-07 30.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CEP14006.1 - 0.0011 18.8 0.6 0.058 13.1 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CEP14006.1 - 0.0095 15.0 0.2 0.021 13.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CEP14006.1 - 0.029 13.7 0.1 0.029 13.7 0.0 2.4 2 0 0 2 2 2 0 RIO1 family IncFII_repA PF02387.10 CEP14006.1 - 1.9 7.6 11.1 3.5 6.7 7.7 1.4 1 0 0 1 1 1 0 IncFII RepA protein family Apis_Csd PF11671.3 CEP14006.1 - 2.6 7.8 8.9 5.6 6.7 6.1 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein ABC_tran_2 PF12848.2 CEP14006.1 - 5.7 6.8 18.4 1.1 9.1 10.0 1.8 2 0 0 2 2 2 0 ABC transporter Asp PF00026.18 CEP14007.1 - 5.2e-79 265.7 0.0 6.2e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP14007.1 - 4.3e-10 39.7 0.0 1.7e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEP14007.1 - 6.4e-06 26.5 0.0 0.18 12.3 0.0 3.3 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 CEP14007.1 - 0.0024 17.4 0.0 0.15 11.5 0.0 2.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal PDEase_I PF00233.14 CEP14009.1 - 1e-49 169.4 0.1 4.6e-27 95.3 1.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CEP14009.1 - 0.0028 17.6 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 HD domain WRC PF08879.5 CEP14009.1 - 0.96 9.1 4.4 10 5.8 3.3 2.4 2 0 0 2 2 2 0 WRC Malic_M PF03949.10 CEP14010.1 - 4.5e-82 275.4 0.2 6.2e-82 274.9 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CEP14010.1 - 2.3e-56 190.2 0.0 4.5e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain zf-RING_3 PF14369.1 CEP14011.1 - 0.0014 18.5 1.1 0.0039 17.1 0.8 1.8 1 0 0 1 1 1 1 zinc-finger RGS PF00615.14 CEP14012.1 - 1.5e-11 44.4 0.2 4.5e-11 42.8 0.2 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain DDE_Tnp_1_4 PF13701.1 CEP14012.1 - 0.032 12.4 0.1 0.047 11.8 0.1 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 F-box PF00646.28 CEP14013.1 - 0.0033 17.0 0.1 0.0071 15.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEP14013.1 - 0.022 14.4 0.3 0.054 13.2 0.2 1.7 1 0 0 1 1 1 0 F-box-like PGM_PMM_I PF02878.11 CEP14014.1 - 6e-36 122.9 0.1 9.9e-36 122.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CEP14014.1 - 1.6e-27 95.8 0.0 4.5e-27 94.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CEP14014.1 - 2e-16 60.1 0.1 6e-16 58.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CEP14014.1 - 1.6e-11 44.0 0.0 4.6e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Autophagy_N PF03986.8 CEP14015.1 - 7.8e-45 152.2 6.3 1.7e-44 151.1 4.4 1.6 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CEP14015.1 - 6.8e-28 96.6 0.8 1.7e-27 95.3 0.6 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CEP14015.1 - 1.5e-14 52.7 3.7 2.7e-14 51.9 2.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CDC27 PF09507.5 CEP14015.1 - 1.2 8.2 10.0 1.7 7.7 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cullin PF00888.17 CEP14016.1 - 1.4e-198 661.2 11.1 1.7e-198 660.9 7.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CEP14016.1 - 1.8e-20 72.5 5.6 6.1e-20 70.8 2.2 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF3658 PF12395.3 CEP14016.1 - 0.027 14.0 0.6 0.076 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function Ank PF00023.25 CEP14017.1 - 1.3e-12 46.8 1.0 3.6e-05 23.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CEP14017.1 - 3.5e-11 43.2 0.7 1.9e-10 40.9 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP14017.1 - 3.5e-10 40.1 0.4 4e-07 30.3 0.1 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP14017.1 - 1.8e-09 36.9 0.4 0.00018 21.4 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CEP14017.1 - 4.2e-09 36.3 0.9 1.7e-05 24.8 0.2 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) LEA_2 PF03168.8 CEP14018.1 - 0.096 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF2839 PF10999.3 CEP14018.1 - 0.14 12.2 0.2 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF1648 PF07853.6 CEP14018.1 - 0.16 11.5 2.0 0.37 10.3 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) DUF900 PF05990.7 CEP14019.1 - 6.8e-06 25.5 0.0 2.3e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 CEP14019.1 - 0.0032 17.2 0.1 0.022 14.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CEP14019.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Arrestin_C PF02752.17 CEP14020.1 - 8.5e-17 61.5 0.1 7e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP14020.1 - 1.2e-16 60.8 0.0 1.5e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CEP14020.1 - 0.00035 20.1 0.0 0.001 18.6 0.0 1.8 1 1 0 1 1 1 1 Arrestin_N terminal like MIF4G PF02854.14 CEP14021.1 - 9.6e-46 155.8 0.7 2.3e-45 154.6 0.5 1.7 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CEP14021.1 - 4.2e-08 32.9 0.1 2.7e-07 30.4 0.1 2.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 CEP14021.1 - 0.00011 21.9 0.1 0.00036 20.2 0.1 1.9 1 0 0 1 1 1 1 MA3 domain Fungal_trans PF04082.13 CEP14022.1 - 5.6e-22 77.8 3.1 2e-21 76.0 2.1 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP14022.1 - 1.3e-10 40.9 6.0 2.3e-10 40.1 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nodulin-like PF06813.8 CEP14023.1 - 6.3e-10 38.7 4.8 1.5e-09 37.4 3.3 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 CEP14023.1 - 3.1e-08 32.7 41.1 6.3e-07 28.4 10.6 3.1 2 1 2 4 4 4 3 Major Facilitator Superfamily FAM176 PF14851.1 CEP14023.1 - 0.027 14.1 2.5 0.98 9.0 0.3 2.5 2 0 0 2 2 2 0 FAM176 family DUF2217 PF10265.4 CEP14024.1 - 2.2 6.9 11.1 2.3 6.8 7.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Rifin_STEVOR PF02009.11 CEP14024.1 - 8.8 5.8 10.1 11 5.6 7.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF1675 PF07897.6 CEP14024.1 - 9.7 5.9 10.8 12 5.7 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Cation_efflux PF01545.16 CEP14025.1 - 4.6e-43 147.3 8.5 5.7e-43 147.0 5.9 1.1 1 0 0 1 1 1 1 Cation efflux family Gemini_C4 PF01492.12 CEP14026.1 - 0.17 11.6 1.1 0.28 10.9 0.8 1.5 1 1 0 1 1 1 0 Geminivirus C4 protein GCR1_C PF12550.3 CEP14027.1 - 7.2e-05 22.5 0.7 0.00015 21.5 0.5 1.7 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes WD40 PF00400.27 CEP14028.1 - 2.8e-27 93.5 12.8 6.3e-11 41.7 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat LisH PF08513.6 CEP14028.1 - 0.015 15.0 0.4 0.027 14.2 0.3 1.4 1 0 0 1 1 1 0 LisH RRM_1 PF00076.17 CEP14029.1 - 5.1e-86 282.3 1.4 8.3e-21 73.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP14029.1 - 3.2e-57 190.4 0.8 1.5e-14 53.7 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP14029.1 - 3.6e-38 129.1 0.6 1.6e-09 37.4 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CEP14029.1 - 8.3e-30 102.2 0.9 8.3e-30 102.2 0.6 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 CEP14029.1 - 3.9e-07 29.7 0.1 3.2 7.6 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CEP14029.1 - 0.0001 21.9 4.3 6.3 6.6 0.3 4.4 3 1 1 4 4 4 3 Limkain b1 OB_RNB PF08206.6 CEP14029.1 - 0.00092 18.6 0.3 3.9 7.0 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease B OB domain CbiG_mid PF11761.3 CEP14029.1 - 0.0017 18.5 0.0 0.65 10.2 0.0 3.1 3 1 0 3 3 3 1 Cobalamin biosynthesis central region DUF4523 PF15023.1 CEP14029.1 - 0.033 13.6 0.0 31 4.0 0.0 3.8 2 1 1 4 4 4 0 Protein of unknown function (DUF4523) SH3_1 PF00018.23 CEP14030.1 - 1.2e-16 59.7 0.7 2.2e-16 58.9 0.5 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP14030.1 - 1.5e-13 49.9 0.1 2.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CEP14030.1 - 6.6e-13 48.0 0.2 1.1e-12 47.3 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain Mito_carr PF00153.22 CEP14031.1 - 3.1e-62 206.3 1.5 3.2e-21 74.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GHMP_kinases_N PF00288.21 CEP14032.1 - 5.5e-07 29.5 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CEP14032.1 - 0.0021 18.1 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transf_3 PF12804.2 CEP14032.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain CotH PF08757.6 CEP14033.1 - 7.1e-39 133.9 0.0 1.2e-38 133.2 0.0 1.3 1 0 0 1 1 1 1 CotH protein Kelch_5 PF13854.1 CEP14034.1 - 1.4e-20 72.7 6.9 4.3e-05 23.3 0.7 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 CEP14034.1 - 4.3e-14 51.9 20.2 0.0017 18.1 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP14034.1 - 1.2e-13 50.5 9.4 0.018 15.1 0.0 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CEP14034.1 - 2.7e-11 42.7 4.0 0.0065 16.1 0.2 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CEP14034.1 - 1.1e-10 40.9 13.9 0.0028 17.1 1.4 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 CEP14034.1 - 2.4e-08 33.9 21.7 0.00013 21.9 0.5 7.5 7 1 0 7 7 7 2 Galactose oxidase, central domain APC_CDC26 PF10471.4 CEP14034.1 - 2.7e-07 31.2 13.0 2.7e-07 31.2 9.0 4.6 4 1 0 4 4 4 1 Anaphase-promoting complex APC subunit 1 EphA2_TM PF14575.1 CEP14034.1 - 0.024 15.0 0.2 0.066 13.6 0.0 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 CEP14034.1 - 0.054 13.0 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 IncA protein DUF3357 PF11837.3 CEP14034.1 - 0.066 13.0 0.5 2.1 8.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) PYRIN PF02758.11 CEP14034.1 - 0.17 11.5 0.3 0.34 10.6 0.2 1.4 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain TMEM154 PF15102.1 CEP14034.1 - 9.2 5.9 0.0 9.2 5.9 0.0 4.1 4 1 1 5 5 5 0 TMEM154 protein family Fungal_trans PF04082.13 CEP14035.1 - 4.9e-19 68.2 3.2 4.9e-19 68.2 2.2 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain AMP-binding PF00501.23 CEP14036.1 - 7e-81 271.7 0.0 9.1e-81 271.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP14036.1 - 5e-16 59.4 0.2 1.2e-15 58.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain S-AdoMet_synt_N PF00438.15 CEP14036.1 - 0.14 12.4 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain F-box-like PF12937.2 CEP14037.1 - 1.1e-05 25.0 0.3 3e-05 23.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like zinc-ribbons_6 PF07191.7 CEP14038.1 - 0.01 15.5 9.6 0.51 10.1 6.7 2.4 1 1 0 1 1 1 0 zinc-ribbons DUF3133 PF11331.3 CEP14038.1 - 0.048 13.2 0.0 0.048 13.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) DZR PF12773.2 CEP14038.1 - 0.49 10.2 11.1 36 4.2 7.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.19 CEP14038.1 - 8.2 6.4 13.1 10 6.1 4.6 2.6 1 1 1 2 2 2 0 B-box zinc finger DUF2797 PF10977.3 CEP14038.1 - 8.4 5.9 7.3 7.5 6.1 4.6 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) Mu-like_Com PF10122.4 CEP14038.1 - 9.2 5.4 7.9 5.3 6.1 2.3 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com ADH_zinc_N PF00107.21 CEP14039.1 - 3.5e-17 62.1 0.0 6.1e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP14039.1 - 1.3e-06 28.1 0.1 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CoA_binding_2 PF13380.1 CEP14039.1 - 0.099 12.8 0.0 0.53 10.4 0.0 2.2 2 1 1 3 3 3 0 CoA binding domain HisG_C PF08029.6 CEP14039.1 - 0.14 12.1 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 HisG, C-terminal domain Lon_C PF05362.8 CEP14040.1 - 5.3e-72 241.4 0.4 9.1e-72 240.6 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CEP14040.1 - 2.2e-17 63.4 0.0 7.8e-17 61.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CEP14040.1 - 1.2e-15 57.7 0.0 3.3e-15 56.3 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 CEP14040.1 - 3.1e-09 36.3 0.0 8.2e-09 35.0 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 CEP14040.1 - 1.1e-06 28.7 0.0 3.7e-05 23.7 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 CEP14040.1 - 2.4e-06 27.3 0.0 1.6e-05 24.6 0.0 2.4 2 1 1 3 3 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CEP14040.1 - 8.6e-06 26.5 0.0 4.4e-05 24.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CEP14040.1 - 4.1e-05 22.7 0.0 0.00019 20.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CEP14040.1 - 0.00047 20.2 0.2 0.0079 16.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CEP14040.1 - 0.00048 20.0 0.0 0.0031 17.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CEP14040.1 - 0.00087 19.5 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 CEP14040.1 - 0.0015 17.2 0.0 0.0028 16.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_2 PF07724.9 CEP14040.1 - 0.0069 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CEP14040.1 - 0.0072 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CEP14040.1 - 0.0091 16.1 0.0 0.034 14.3 0.0 2.1 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.1 CEP14040.1 - 0.011 15.1 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP14040.1 - 0.014 15.0 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 CEP14040.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 NTPase MobB PF03205.9 CEP14040.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 CEP14040.1 - 0.034 13.5 0.0 0.092 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.17 CEP14040.1 - 0.034 14.0 0.1 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_23 PF13476.1 CEP14040.1 - 0.036 14.3 0.0 0.099 12.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.6 CEP14040.1 - 0.038 13.5 0.0 0.094 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CEP14040.1 - 0.046 12.9 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CEP14040.1 - 0.061 13.2 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CEP14040.1 - 0.068 12.7 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CEP14040.1 - 0.08 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 CEP14040.1 - 0.091 13.0 0.1 0.95 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 CEP14040.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain F-box-like PF12937.2 CEP14041.1 - 0.00052 19.6 0.2 0.0032 17.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like Mito_fiss_reg PF05308.6 CEP14041.1 - 0.014 14.8 0.6 0.023 14.0 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator F-box PF00646.28 CEP14041.1 - 0.11 12.1 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 F-box domain DUF3292 PF11696.3 CEP14041.1 - 0.14 10.0 1.4 0.18 9.6 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Med9 PF07544.8 CEP14041.1 - 0.36 10.5 2.0 21 4.9 0.0 3.6 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DNA_binding_1 PF01035.15 CEP14042.1 - 2.5e-20 71.9 0.0 3.5e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Striatin PF08232.7 CEP14043.1 - 3.3e-40 137.5 0.1 3.3e-40 137.5 0.1 3.0 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 CEP14043.1 - 9e-35 117.3 6.3 1e-10 41.0 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEP14043.1 - 9.5e-05 21.3 4.7 0.0012 17.7 0.3 2.9 2 1 1 3 3 3 2 Nup133 N terminal like PH_8 PF15409.1 CEP14043.1 - 0.04 13.9 0.0 5.6 7.1 0.0 2.9 2 1 1 3 3 3 0 Pleckstrin homology domain Pho88 PF10032.4 CEP14044.1 - 3.6e-47 160.0 0.0 4.1e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ras PF00071.17 CEP14045.1 - 6.8e-59 197.8 0.4 7.9e-59 197.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP14045.1 - 2e-17 63.7 0.0 2.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP14045.1 - 5.4e-17 61.5 0.1 6.6e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEP14045.1 - 1.6e-08 34.4 0.0 2.2e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEP14045.1 - 2.8e-08 33.1 0.0 3.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP14045.1 - 2.1e-07 30.5 0.1 7.5e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CEP14045.1 - 0.00017 20.8 0.1 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CEP14045.1 - 0.0013 18.0 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.1 CEP14045.1 - 0.023 14.8 0.0 1.8 8.7 0.0 2.3 1 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 CEP14045.1 - 0.032 13.4 0.1 0.075 12.2 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CEP14045.1 - 0.12 12.3 0.0 3.2 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Complex1_LYR PF05347.10 CEP14046.1 - 9.7e-07 28.4 0.6 1.3e-05 24.9 0.3 2.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEP14046.1 - 1.4e-05 25.1 0.9 3e-05 24.1 0.2 1.9 2 0 0 2 2 2 1 Complex1_LYR-like Ran-binding PF05508.6 CEP14046.1 - 0.025 13.4 0.1 0.25 10.1 0.0 2.2 2 0 0 2 2 2 0 RanGTP-binding protein GHL1-3 PF11308.3 CEP14046.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 Arm PF00514.18 CEP14047.1 - 4.4e-14 51.6 3.2 0.00022 20.9 0.0 7.4 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CEP14047.1 - 0.0003 21.1 0.8 1.5 9.3 0.0 5.0 5 1 1 6 6 6 1 HEAT-like repeat Cytidylate_kin PF02224.13 CEP14048.1 - 1.5e-40 138.2 5.8 8.1e-33 113.0 1.0 2.1 2 0 0 2 2 2 2 Cytidylate kinase AAA_17 PF13207.1 CEP14048.1 - 6.9e-12 46.2 0.1 2.7e-11 44.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 CEP14048.1 - 6.1e-07 29.5 0.5 0.00032 20.6 0.0 2.2 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_18 PF13238.1 CEP14048.1 - 0.00031 21.0 0.1 0.0016 18.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 CEP14048.1 - 0.0015 18.4 0.8 0.0059 16.4 0.1 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.1 CEP14048.1 - 0.0052 16.6 0.3 0.019 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain ADK PF00406.17 CEP14048.1 - 0.008 16.0 0.1 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase Fijivirus_P9-2 PF06837.6 CEP14048.1 - 0.016 14.3 0.4 0.026 13.6 0.3 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein ABC_tran PF00005.22 CEP14048.1 - 0.097 12.9 0.9 0.17 12.1 0.6 1.7 1 1 0 1 1 1 0 ABC transporter Zip PF02535.17 CEP14049.1 - 1.2e-38 132.8 17.0 9.2e-38 130.0 11.8 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter 7TM-7TMR_HD PF07698.6 CEP14049.1 - 0.0036 16.7 7.4 0.0036 16.7 5.2 2.4 2 0 0 2 2 2 1 7TM receptor with intracellular HD hydrolase DNA_pol3_beta_3 PF02768.10 CEP14049.1 - 0.039 13.5 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain DUF308 PF03729.8 CEP14049.1 - 0.05 13.6 0.1 0.05 13.6 0.1 3.4 4 0 0 4 4 4 0 Short repeat of unknown function (DUF308) FTR1 PF03239.9 CEP14049.1 - 0.15 10.9 5.0 0.074 11.9 1.8 1.8 2 0 0 2 2 2 0 Iron permease FTR1 family ABC2_membrane_3 PF12698.2 CEP14049.1 - 0.55 9.2 8.3 4.8 6.1 3.3 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein SDA1 PF05285.7 CEP14050.1 - 0.29 10.3 26.9 0.56 9.4 18.7 1.5 1 0 0 1 1 1 0 SDA1 Astro_capsid PF03115.9 CEP14050.1 - 0.69 8.0 7.9 0.89 7.7 5.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor F-box-like PF12937.2 CEP14051.1 - 5.3e-07 29.2 0.5 9.9e-07 28.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP14051.1 - 0.00011 21.7 0.0 0.00054 19.5 0.0 2.3 2 0 0 2 2 2 1 F-box domain eIF2A PF08662.6 CEP14052.1 - 3.5e-41 141.0 7.8 5.9e-37 127.2 1.2 5.4 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CEP14052.1 - 4.1e-06 26.3 0.0 1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CEP14052.1 - 3.7e-05 23.4 0.8 0.0063 16.3 0.2 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat RRM_6 PF14259.1 CEP14052.1 - 0.00033 20.5 0.0 0.00091 19.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP14052.1 - 0.01 15.6 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.17 CEP14053.1 - 1.8e-45 154.7 1.2 1.8e-45 154.7 0.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CEP14053.1 - 1.4e-29 101.7 1.5 1.4e-29 101.7 1.1 2.3 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain JAB PF01398.16 CEP14054.1 - 1.9e-18 66.2 0.0 3.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 CEP14054.1 - 1.5e-17 63.5 0.9 2.7e-17 62.7 0.6 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 CEP14054.1 - 1.9e-07 30.5 0.0 4.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Clat_adaptor_s PF01217.15 CEP14055.1 - 5e-54 181.8 2.8 5.7e-54 181.6 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.16 CEP14056.1 - 1.9e-54 184.4 0.0 2.2e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Thioredoxin PF00085.15 CEP14057.1 - 1e-36 124.7 0.2 3.9e-23 81.1 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 CEP14057.1 - 3.6e-28 98.6 5.1 8.8e-18 64.7 2.7 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEP14057.1 - 1.3e-05 25.1 8.3 0.013 15.5 0.0 5.6 4 1 2 6 6 6 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CEP14057.1 - 4.6e-05 23.5 1.3 0.14 12.3 0.1 4.3 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CEP14057.1 - 0.0022 17.9 0.0 0.0085 16.0 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like 6PGD PF00393.14 CEP14058.1 - 3.5e-139 462.9 0.0 4.4e-139 462.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CEP14058.1 - 9.4e-55 184.8 0.0 1.4e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CEP14058.1 - 0.0029 17.6 0.0 0.032 14.2 0.0 2.5 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CEP14058.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CEP14058.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Band_7 PF01145.20 CEP14059.1 - 1.8e-31 109.4 0.2 2.3e-31 109.0 0.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CEP14059.1 - 0.001 18.6 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.20 CEP14060.1 - 4.3e-29 101.6 0.3 6e-29 101.2 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family CAP PF00188.21 CEP14061.1 - 1.5e-24 86.8 7.1 1.9e-24 86.5 4.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ATP_bind_4 PF01902.12 CEP14062.1 - 2.4e-27 95.7 0.0 3.3e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 ATP-binding region ACBP PF00887.14 CEP14063.1 - 7.1e-24 83.2 0.1 1.4e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.25 CEP14063.1 - 9.5e-18 63.0 0.5 9.1e-10 37.8 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CEP14063.1 - 4.6e-16 58.9 0.2 8e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP14063.1 - 9.1e-15 54.7 0.1 3.6e-10 40.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP14063.1 - 5.3e-14 51.9 0.1 8.2e-07 29.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP14063.1 - 5.7e-13 47.7 0.1 1.2e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat WD40 PF00400.27 CEP14064.1 - 3.5e-22 77.3 11.6 0.00018 21.2 0.1 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat CPSF_A PF03178.10 CEP14064.1 - 0.00031 19.9 0.0 0.0043 16.1 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region Nucleoporin_N PF08801.6 CEP14064.1 - 0.0044 15.8 0.0 0.44 9.2 0.0 2.5 2 0 0 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 CEP14064.1 - 0.0051 16.3 1.1 0.17 11.3 0.3 2.7 3 1 1 4 4 4 2 PQQ-like domain GLE1 PF07817.8 CEP14066.1 - 5.9e-42 143.3 0.6 5.9e-42 143.3 0.4 2.5 2 1 1 3 3 3 1 GLE1-like protein Spc97_Spc98 PF04130.8 CEP14067.1 - 3.1e-128 428.4 10.8 5.1e-128 427.7 7.5 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family Allantoicase PF03561.10 CEP14068.1 - 1.5e-84 280.9 0.0 1.6e-45 154.2 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 CEP14068.1 - 2.3e-52 176.6 0.0 3.6e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Dor1 PF04124.7 CEP14069.1 - 8.2e-65 218.4 4.5 1.6e-64 217.4 3.1 1.5 1 0 0 1 1 1 1 Dor1-like family DUF2450 PF10475.4 CEP14069.1 - 0.011 14.7 0.2 0.02 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 CEP14069.1 - 0.024 14.3 0.9 0.056 13.1 0.0 2.1 3 0 0 3 3 3 0 Exocyst complex component Sec5 Spc7_C2 PF15577.1 CEP14069.1 - 0.04 13.5 0.7 1.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Spc7_C2 PG_binding_3 PF09374.5 CEP14069.1 - 0.07 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain MULE PF10551.4 CEP14070.1 - 9.2e-13 48.1 0.1 2.6e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Transglut_prok PF09017.5 CEP14070.1 - 0.0067 15.5 0.7 0.18 10.9 0.1 2.2 1 1 1 2 2 2 2 Microbial transglutaminase Cu-oxidase PF00394.17 CEP14071.1 - 4.6e-35 120.8 0.0 2.3e-34 118.6 0.0 2.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CEP14071.1 - 1.6e-31 108.4 0.9 7.9e-31 106.2 0.6 2.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CEP14071.1 - 3e-19 68.8 18.6 9.8e-17 60.7 6.2 4.0 2 2 0 2 2 2 2 Multicopper oxidase A2M PF00207.17 CEP14071.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Alpha-2-macroglobulin family DUF3425 PF11905.3 CEP14072.1 - 1.3e-16 60.7 8.0 1.6e-14 53.9 5.5 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CEP14072.1 - 3.7e-09 36.4 7.9 9.3e-09 35.1 5.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP14072.1 - 0.011 15.5 13.9 0.011 15.5 9.7 2.0 2 0 0 2 2 2 0 Basic region leucine zipper HTH_29 PF13551.1 CEP14073.1 - 3.8e-08 33.4 0.0 8.7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.1 CEP14073.1 - 4.3e-07 29.7 0.0 9e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP14073.1 - 9.1e-07 28.7 0.3 1e-05 25.4 0.1 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP14073.1 - 5e-05 22.8 0.1 0.0011 18.5 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 CEP14073.1 - 0.0001 22.1 0.3 0.00025 20.9 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 CEP14073.1 - 0.00016 22.3 0.0 0.0005 20.8 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.2 CEP14073.1 - 0.084 13.1 0.0 8.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain ubiquitin PF00240.18 CEP14074.1 - 6e-24 83.2 0.1 6.5e-24 83.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CEP14074.1 - 6.2e-14 51.4 0.0 6.6e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEP14074.1 - 0.0099 16.1 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain SbcCD_C PF13558.1 CEP14075.1 - 4.3e-09 36.1 0.0 1.3e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad50_zn_hook PF04423.9 CEP14075.1 - 8.7e-06 25.1 0.1 8.7e-06 25.1 0.1 5.5 5 1 0 5 5 5 1 Rad50 zinc hook motif NPV_P10 PF05531.7 CEP14075.1 - 2 8.7 57.6 1.3 9.2 5.0 9.8 7 5 1 8 8 8 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.24 CEP14076.1 - 9.3e-43 145.6 0.1 1.6e-42 144.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP14076.1 - 7.9e-24 83.3 0.1 1.9e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UvrD-helicase PF00580.16 CEP14076.1 - 0.0073 15.6 3.0 0.064 12.5 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.1 CEP14076.1 - 0.11 11.5 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Gag_spuma PF03276.9 CEP14076.1 - 0.7 8.1 16.1 1 7.5 11.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Shisa PF13908.1 CEP14076.1 - 1.7 8.8 7.1 3.2 7.9 4.9 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator API5 PF05918.6 CEP14076.1 - 6.7 5.0 9.6 9.9 4.5 6.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) F-box-like PF12937.2 CEP14077.1 - 8.6e-05 22.1 3.1 8.6e-05 22.1 2.2 2.5 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 CEP14078.1 - 1.5e-22 79.8 32.3 3e-22 78.8 22.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HTH_23 PF13384.1 CEP14080.1 - 0.07 12.8 0.4 0.38 10.4 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain SH3_9 PF14604.1 CEP14081.1 - 1.1e-07 31.3 0.1 2.1e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP14081.1 - 1.8e-07 30.4 0.1 3.1e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP14081.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Myb_DNA-bind_5 PF13873.1 CEP14082.1 - 0.035 13.9 0.6 0.22 11.4 0.6 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Apc4_WD40 PF12894.2 CEP14083.1 - 6.4e-07 28.7 0.0 4.9e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Apc4 PF12896.2 CEP14083.1 - 3.2e-06 26.6 1.0 5.6e-06 25.8 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Med21 PF11221.3 CEP14083.1 - 2.6 7.9 8.0 0.27 11.1 2.2 1.8 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Pet127 PF08634.5 CEP14086.1 - 0.0087 15.2 1.2 0.0094 15.1 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Fcf2 PF08698.6 CEP14086.1 - 0.052 13.5 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing zf-CCHC PF00098.18 CEP14087.1 - 1.8e-06 27.5 10.1 6.7e-05 22.6 1.2 2.5 2 0 0 2 2 2 2 Zinc knuckle DUF2951 PF11166.3 CEP14087.1 - 0.061 13.1 1.0 0.09 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-CCHC_2 PF13696.1 CEP14087.1 - 0.19 11.2 4.8 3.6 7.1 0.1 2.3 1 1 1 2 2 2 0 Zinc knuckle Abhydrolase_6 PF12697.2 CEP14089.1 - 1.9e-13 50.8 0.1 3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP14089.1 - 2e-08 34.1 0.8 4e-08 33.1 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP14089.1 - 5.8e-05 22.7 0.6 0.00016 21.3 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CEP14089.1 - 0.007 15.9 0.1 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase UPF0227 PF05728.7 CEP14089.1 - 0.0075 16.0 0.1 0.065 12.9 0.1 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) YjgP_YjgQ PF03739.9 CEP14090.1 - 0.019 13.7 4.1 0.026 13.2 2.8 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Plasmodium_Vir PF05795.6 CEP14090.1 - 0.076 12.2 1.0 0.11 11.6 0.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1421 PF07223.6 CEP14090.1 - 0.28 10.9 13.8 0.41 10.3 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) DUF3963 PF13124.1 CEP14090.1 - 0.3 10.9 2.2 0.73 9.6 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3963) DUF572 PF04502.8 CEP14090.1 - 0.54 9.4 16.6 0.79 8.8 11.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TP53IP5 PF15331.1 CEP14090.1 - 0.67 9.8 15.9 1.2 8.9 11.0 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 AAA_23 PF13476.1 CEP14090.1 - 5.4 7.2 14.1 9.2 6.5 9.8 1.4 1 0 0 1 1 1 0 AAA domain DUF4637 PF15470.1 CEP14090.1 - 5.7 6.5 10.4 9.9 5.7 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pkinase PF00069.20 CEP14092.1 - 2.6e-58 197.2 0.0 2.6e-58 197.2 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14092.1 - 3.2e-41 141.1 0.0 6.6e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14092.1 - 0.0019 17.1 0.0 0.0046 15.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Serinc PF03348.10 CEP14092.1 - 7 5.2 6.6 13 4.3 4.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ribosomal_S19e PF01090.14 CEP14093.1 - 5.5e-60 200.8 0.1 6.2e-60 200.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RhoGAP PF00620.22 CEP14094.1 - 3e-39 134.0 0.3 5.5e-39 133.2 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain SprT-like PF10263.4 CEP14094.1 - 0.029 14.0 0.3 0.062 12.9 0.2 1.5 1 0 0 1 1 1 0 SprT-like family Carn_acyltransf PF00755.15 CEP14095.1 - 7.9e-143 476.6 0.0 9.2e-143 476.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Arrestin_N PF00339.24 CEP14096.1 - 5e-18 65.3 4.2 1.7e-16 60.3 0.0 3.5 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP14096.1 - 2.2e-14 53.7 5.7 1.1e-10 41.7 0.1 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 CEP14096.1 - 0.0041 15.9 0.2 0.03 13.1 0.0 2.0 1 1 0 2 2 2 1 Vacuolar protein sorting-associated protein 26 VPS9 PF02204.13 CEP14097.1 - 8.8e-14 51.4 1.7 1.9e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain WW PF00397.21 CEP14098.1 - 2.6e-07 30.3 1.3 6.3e-07 29.1 0.9 1.7 1 0 0 1 1 1 1 WW domain DUF1183 PF06682.7 CEP14098.1 - 0.0038 16.8 10.5 0.0038 16.8 7.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) DUF1091 PF06477.8 CEP14100.1 - 0.083 13.3 0.1 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) NRDE PF05742.7 CEP14100.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NRDE protein RGS PF00615.14 CEP14103.1 - 5.2e-20 71.7 0.0 3.5e-19 69.0 0.0 2.5 2 1 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 CEP14103.1 - 2.1e-06 27.3 0.4 0.0086 15.7 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DJ-1_PfpI PF01965.19 CEP14104.1 - 4e-20 71.7 0.0 9.5e-20 70.5 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 CEP14104.1 - 0.00036 19.9 0.2 0.0011 18.4 0.1 1.8 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family T2SE PF00437.15 CEP14104.1 - 0.17 10.7 0.8 0.26 10.1 0.6 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein EF-hand_4 PF12763.2 CEP14105.1 - 2.6e-41 139.5 0.0 1.9e-16 59.6 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CEP14105.1 - 5e-08 32.9 0.0 0.051 13.7 0.0 3.7 2 1 0 2 2 2 2 EF-hand domain pair UBA PF00627.26 CEP14105.1 - 1.5e-05 24.6 0.2 3.3e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 CEP14105.1 - 3.7e-05 22.7 6.4 0.93 8.9 0.0 5.1 6 0 0 6 6 6 2 EF hand Myosin_tail_1 PF01576.14 CEP14105.1 - 5e-05 21.2 16.0 5e-05 21.2 11.1 2.0 1 1 1 2 2 2 1 Myosin tail EF-hand_8 PF13833.1 CEP14105.1 - 0.00093 18.7 0.0 0.1 12.2 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain pair Reo_sigmaC PF04582.7 CEP14105.1 - 0.015 14.4 13.4 0.019 14.1 3.1 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 CEP14105.1 - 0.074 12.6 24.4 0.45 10.0 8.4 2.6 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 CEP14105.1 - 0.26 11.2 13.7 0.45 10.4 0.7 3.7 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Sec8_exocyst PF04048.9 CEP14105.1 - 0.52 9.9 15.5 1.1 8.8 2.9 2.8 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF4201 PF13870.1 CEP14105.1 - 0.61 9.5 26.1 2.2 7.6 10.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Seryl_tRNA_N PF02403.17 CEP14105.1 - 0.96 9.4 25.2 0.14 12.2 6.9 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 CEP14105.1 - 1.1 9.1 35.7 7.2 6.4 5.3 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 CEP14105.1 - 1.6 7.2 23.7 16 4.0 16.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.6 CEP14105.1 - 5.4 6.9 14.1 0.51 10.2 3.0 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 R3H PF01424.17 CEP14106.1 - 2.4e-09 36.7 0.0 4.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 CEP14106.1 - 7.4e-07 29.0 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP14106.1 - 0.0001 22.0 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP14106.1 - 0.0002 20.9 0.0 0.00043 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PT PF04886.7 CEP14106.1 - 0.012 14.8 5.4 0.012 14.8 3.8 2.5 2 1 0 2 2 2 0 PT repeat RRM_2 PF04059.7 CEP14106.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Corona_nucleoca PF00937.13 CEP14106.1 - 0.71 8.7 12.4 0.043 12.7 4.4 2.0 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Cut12 PF11500.3 CEP14106.1 - 1.8 8.2 6.2 0.41 10.3 1.7 1.8 2 0 0 2 2 2 0 Spindle pole body formation-associated protein RabGAP-TBC PF00566.13 CEP14107.1 - 5.5e-45 153.4 0.2 5.5e-45 153.4 0.1 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 CEP14107.1 - 6.4e-21 73.6 0.0 2.1e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 GRAM domain DUF2036 PF09724.4 CEP14108.1 - 5.6e-61 206.4 0.1 7e-61 206.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Xol-1_GHMP-like PF09109.5 CEP14108.1 - 0.035 14.2 1.0 0.061 13.4 0.7 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like SR-25 PF10500.4 CEP14109.1 - 0.0096 15.4 9.4 0.0096 15.4 6.5 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pox_C7_F8A PF03287.9 CEP14109.1 - 0.018 14.7 0.3 0.032 13.9 0.2 1.4 1 0 0 1 1 1 0 Poxvirus C7/F8A protein DUF3138 PF11336.3 CEP14109.1 - 0.24 9.5 2.8 0.35 8.9 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sec20 PF03908.8 CEP14109.1 - 0.33 10.6 6.5 0.23 11.2 2.6 2.1 2 0 0 2 2 2 0 Sec20 DUF3513 PF12026.3 CEP14109.1 - 0.38 10.2 10.7 4.2 6.8 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) Med15 PF09606.5 CEP14109.1 - 1.5 6.9 18.9 1.8 6.6 13.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CEP14109.1 - 2.4 6.9 13.3 3.6 6.3 9.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DivIC PF04977.10 CEP14109.1 - 2.5 7.6 13.8 0.73 9.3 4.5 2.6 2 0 0 2 2 2 0 Septum formation initiator Sina PF03145.11 CEP14110.1 - 3.4e-05 23.5 19.5 0.042 13.5 3.4 3.9 1 1 3 4 4 4 3 Seven in absentia protein family zf-RING_6 PF14835.1 CEP14110.1 - 4.3e-05 23.2 6.6 0.00011 21.8 4.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CEP14110.1 - 9.2e-05 22.2 11.9 9.2e-05 22.2 8.2 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CEP14110.1 - 0.00041 20.1 15.0 0.00041 20.1 10.4 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP14110.1 - 0.0005 20.0 15.6 0.0005 20.0 10.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP14110.1 - 0.00094 18.7 16.6 0.0039 16.8 11.5 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.13 CEP14110.1 - 0.0014 18.9 5.8 0.0014 18.9 4.0 4.7 2 2 3 5 5 5 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 CEP14110.1 - 0.0063 16.1 12.5 0.0063 16.1 8.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP14110.1 - 6.5 6.5 22.0 0.15 11.8 9.9 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Ion_trans PF00520.26 CEP14111.1 - 0.0034 16.6 1.1 0.0034 16.6 0.8 1.5 2 0 0 2 2 2 1 Ion transport protein TSC22 PF01166.13 CEP14111.1 - 0.08 12.9 2.5 0.14 12.1 1.7 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Radial_spoke_3 PF06098.6 CEP14111.1 - 0.13 11.2 4.9 0.16 10.9 3.4 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 DUF4047 PF13256.1 CEP14111.1 - 0.48 10.4 6.0 11 5.9 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) PH PF00169.24 CEP14112.1 - 7.9e-10 38.8 1.9 1.5e-09 37.9 1.3 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CEP14112.1 - 2.6e-05 24.4 1.5 2.6e-05 24.4 1.1 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 CEP14112.1 - 0.029 14.5 0.6 0.072 13.2 0.4 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Fasciclin PF02469.17 CEP14113.1 - 2.4e-52 176.2 0.1 8.5e-16 58.1 0.1 5.2 5 0 0 5 5 5 5 Fasciclin domain Metallophos PF00149.23 CEP14114.1 - 1.2e-37 129.3 0.4 1.8e-37 128.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 CEP14114.1 - 6.7e-29 99.7 2.3 1.4e-28 98.6 0.4 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 CEP14114.1 - 1.4e-22 79.0 4.7 8.8e-18 63.7 0.5 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CEP14114.1 - 4.2e-14 51.4 6.5 0.00022 20.7 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP14114.1 - 3.8e-11 42.0 6.3 0.0021 17.8 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEP14114.1 - 6.6e-06 25.9 3.4 0.086 13.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEP14114.1 - 0.00016 21.4 0.0 0.0056 16.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP14114.1 - 0.00017 21.8 0.1 0.15 12.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP14114.1 - 0.00019 22.0 0.0 0.12 13.0 0.0 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP14114.1 - 0.00042 20.1 1.6 0.048 13.5 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP14114.1 - 0.0041 17.6 0.0 0.077 13.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat UvrD-helicase PF00580.16 CEP14114.1 - 0.012 14.9 0.2 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain TPR_7 PF13176.1 CEP14114.1 - 0.02 14.6 0.1 6.4 6.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP14114.1 - 0.046 13.5 8.6 0.18 11.6 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CEP14114.1 - 0.049 13.7 4.8 0.048 13.7 1.2 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CEP14114.1 - 0.074 12.9 0.1 18 5.3 0.0 2.9 2 1 1 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 CEP14114.1 - 0.082 12.1 0.1 16 4.8 0.0 2.8 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.13 CEP14114.1 - 2.5 8.0 5.5 2.7 7.9 0.7 2.8 1 1 2 3 3 3 0 MIT (microtubule interacting and transport) domain La PF05383.12 CEP14115.1 - 7.4e-21 73.7 0.6 1.3e-20 72.9 0.4 1.4 1 0 0 1 1 1 1 La domain Nuc_sug_transp PF04142.10 CEP14116.1 - 3.7e-92 307.8 9.5 4.7e-92 307.4 6.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CEP14116.1 - 2.2e-07 30.9 3.4 2.2e-07 30.9 2.3 2.5 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 CEP14116.1 - 3.9e-07 30.2 1.3 3.9e-07 30.2 0.9 2.7 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 CEP14116.1 - 2.5e-05 23.9 16.0 9.9e-05 22.0 0.3 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family TraG-D_C PF12696.2 CEP14116.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG HAUS6_N PF14661.1 CEP14120.1 - 0.24 10.7 8.4 0.08 12.2 3.4 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Cut8_N PF14482.1 CEP14120.1 - 0.41 10.6 4.1 2.7 8.0 0.8 3.1 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Herpes_capsid PF06112.6 CEP14122.1 - 0.15 12.1 5.3 0.31 11.0 3.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cellulase PF00150.13 CEP14123.1 - 1.2e-15 57.4 0.6 3.5e-11 42.8 0.0 3.7 2 2 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 CEP14123.1 - 0.016 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DUF2458 PF10454.4 CEP14124.1 - 3.2e-10 40.0 12.4 5.9e-10 39.2 8.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.6 CEP14124.1 - 1.6e-07 31.0 14.0 2.1e-06 27.3 9.7 2.0 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein EutB PF06751.6 CEP14124.1 - 0.0023 16.3 0.1 0.0027 16.1 0.1 1.2 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) OmpH PF03938.9 CEP14124.1 - 0.022 14.6 9.3 0.026 14.4 5.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ExbD PF02472.11 CEP14124.1 - 0.062 13.2 2.0 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR TBPIP PF07106.8 CEP14124.1 - 0.59 9.6 15.7 0.37 10.3 1.2 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vps54 PF07928.7 CEP14124.1 - 0.96 9.5 5.7 0.56 10.3 1.1 2.2 1 1 1 2 2 2 0 Vps54-like protein Rep_4 PF05797.6 CEP14125.1 - 0.17 10.5 3.3 0.19 10.3 2.3 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Ndc1_Nup PF09531.5 CEP14126.1 - 1.6 7.0 4.1 1.8 6.8 2.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PLRV_ORF5 PF01690.12 CEP14126.1 - 5.5 6.0 11.0 5.9 5.9 7.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1003 PF06210.6 CEP14126.1 - 8.9 6.2 8.1 28 4.7 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) Menin PF05053.8 CEP14128.1 - 1.3 7.0 21.4 0.6 8.2 4.0 2.2 2 0 0 2 2 2 0 Menin AMP-binding PF00501.23 CEP14131.1 - 1.1e-92 310.5 0.0 1.5e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme KLRAQ PF10205.4 CEP14132.1 - 1.1e-15 57.4 10.0 1.1e-15 57.4 7.0 6.1 3 3 2 5 5 5 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.4 CEP14132.1 - 5e-13 48.8 7.4 5e-13 48.8 5.1 3.9 2 1 1 4 4 4 1 Predicted coiled-coil domain-containing protein ERM PF00769.14 CEP14132.1 - 0.0052 16.3 87.1 0.014 14.9 9.5 4.4 4 0 0 4 4 4 4 Ezrin/radixin/moesin family bZIP_2 PF07716.10 CEP14132.1 - 0.014 15.2 3.3 0.014 15.2 2.3 10.0 9 2 2 12 12 12 0 Basic region leucine zipper DivIC PF04977.10 CEP14132.1 - 0.017 14.5 3.1 0.017 14.5 2.2 9.4 7 3 2 9 9 9 0 Septum formation initiator Utp14 PF04615.8 CEP14133.1 - 1.9e-172 575.2 100.9 1.9e-172 575.2 70.0 2.5 1 1 1 2 2 2 1 Utp14 protein Lipase_3 PF01764.20 CEP14134.1 - 5.5e-19 68.1 0.0 1.9e-18 66.3 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) NIF PF03031.13 CEP14134.1 - 2.6e-13 49.9 0.0 7.2e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PPR_2 PF13041.1 CEP14135.1 - 1.1e-78 258.9 22.5 8.1e-12 44.9 0.0 18.7 14 6 7 21 21 21 15 PPR repeat family PPR_3 PF13812.1 CEP14135.1 - 2.9e-53 173.7 19.3 0.00013 21.9 0.0 20.0 21 0 0 21 21 21 12 Pentatricopeptide repeat domain PPR PF01535.15 CEP14135.1 - 6.5e-50 163.6 20.6 2.5e-05 23.9 0.0 18.6 23 0 0 23 23 23 10 PPR repeat PPR_1 PF12854.2 CEP14135.1 - 9.4e-41 136.9 0.4 1e-05 24.8 0.0 14.2 17 0 0 17 17 17 7 PPR repeat TPR_19 PF14559.1 CEP14135.1 - 1.6e-08 34.7 14.8 0.75 10.1 0.2 9.3 8 2 3 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP14135.1 - 2.1e-07 30.9 2.0 69 4.4 0.0 9.6 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP14135.1 - 6.1e-06 26.0 11.7 0.92 9.4 0.0 8.0 7 2 2 9 9 9 3 Tetratricopeptide repeat RPM2 PF08579.6 CEP14135.1 - 0.00085 19.4 12.7 0.0023 18.0 0.7 6.0 6 1 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) Apc3 PF12895.2 CEP14135.1 - 0.0012 18.9 17.8 3.1 8.0 0.1 6.2 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Paramyxo_PNT PF13825.1 CEP14135.1 - 0.029 13.5 0.1 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus TPR_16 PF13432.1 CEP14135.1 - 0.086 13.5 7.6 83 4.0 0.0 7.4 9 1 0 9 9 9 0 Tetratricopeptide repeat RIX1 PF08167.7 CEP14136.1 - 0.054 13.1 0.1 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis UMPH-1 PF05822.7 CEP14137.1 - 6e-83 277.9 1.5 7e-83 277.7 1.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 CEP14137.1 - 0.01 16.0 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP14137.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RVT_1 PF00078.22 CEP14139.1 - 1.4e-10 40.9 0.1 2.9e-09 36.5 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3808 PF10300.4 CEP14140.1 - 6.5e-90 301.9 9.6 1.7e-89 300.5 6.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 CEP14140.1 - 0.00079 19.0 3.8 0.028 14.0 0.2 3.7 2 1 1 3 3 3 1 TPR repeat RGS PF00615.14 CEP14141.1 - 1.4e-21 76.7 0.1 9.2e-20 70.9 0.0 2.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 CEP14141.1 - 8.6e-11 41.4 0.2 0.0001 21.9 0.1 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Chitin_synth_1 PF01644.12 CEP14142.1 - 3.9e-86 286.9 0.8 6.1e-86 286.2 0.6 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CEP14142.1 - 2e-28 97.8 0.3 6.3e-28 96.2 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEP14142.1 - 1e-18 67.0 0.0 1.6e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP14142.1 - 9.6e-08 31.9 0.1 2.4e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP14142.1 - 1e-07 31.9 0.0 4.9e-07 29.7 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Ric8 PF10165.4 CEP14143.1 - 9.2e-09 34.6 9.0 0.00063 18.6 2.1 3.3 1 1 0 3 3 3 3 Guanine nucleotide exchange factor synembryn Arm PF00514.18 CEP14143.1 - 4.4e-08 32.6 11.0 0.25 11.2 0.0 8.2 10 0 0 10 10 10 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEP14143.1 - 0.012 15.8 1.4 9 6.6 0.0 4.0 5 0 0 5 5 5 0 HEAT repeats CBFB_NFYA PF02045.10 CEP14145.1 - 2.8e-29 101.4 7.1 2.8e-29 101.4 4.9 1.8 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Pepsin-I3 PF06394.8 CEP14145.1 - 2.9 7.6 13.2 2.2 8.0 7.7 1.8 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain TFIIS_M PF07500.9 CEP14146.1 - 4.4e-25 87.9 0.1 9.8e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CEP14146.1 - 3.9e-20 71.1 5.9 6.3e-20 70.5 4.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CEP14146.1 - 1.3e-12 47.0 3.2 3.1e-12 45.8 2.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LEDGF PF11467.3 CEP14146.1 - 2.5e-06 27.1 1.2 5e-06 26.1 0.8 1.5 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) RE_XcyI PF09571.5 CEP14146.1 - 0.049 12.4 0.3 0.07 11.9 0.2 1.2 1 0 0 1 1 1 0 XcyI restriction endonuclease DUF2854 PF11016.3 CEP14147.1 - 0.02 14.4 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) DUF3397 PF11877.3 CEP14147.1 - 0.044 13.7 11.0 0.4 10.6 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) DPBB_1 PF03330.13 CEP14148.1 - 1.5e-11 44.0 0.7 1.1e-10 41.3 0.5 2.4 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP14148.1 - 0.00079 19.0 1.4 0.0016 18.1 0.2 1.9 1 1 1 2 2 2 1 Barwin family Peptidase_M41 PF01434.13 CEP14149.1 - 3e-71 239.2 0.0 4.4e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CEP14149.1 - 2.5e-43 147.4 0.0 5.3e-43 146.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CEP14149.1 - 6.8e-05 22.9 0.0 0.00026 21.1 0.0 2.1 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CEP14149.1 - 7.7e-05 23.5 0.0 0.0004 21.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP14149.1 - 0.00017 21.7 0.1 0.045 13.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEP14149.1 - 0.00089 18.9 0.1 0.0076 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CEP14149.1 - 0.0024 16.6 0.0 0.004 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CEP14149.1 - 0.0032 16.5 0.0 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CEP14149.1 - 0.0034 17.1 0.6 0.0089 15.7 0.4 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CEP14149.1 - 0.0039 17.2 0.1 0.059 13.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CEP14149.1 - 0.01 15.7 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 CEP14149.1 - 0.022 14.1 0.5 0.056 12.8 0.2 1.8 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CEP14149.1 - 0.028 13.8 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CEP14149.1 - 0.033 13.2 0.1 0.084 11.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 CEP14149.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEP14149.1 - 0.078 13.2 0.1 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEP14149.1 - 0.088 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CEP14149.1 - 0.14 11.2 0.2 0.3 10.2 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PsbM PF05151.7 CEP14149.1 - 0.16 11.6 1.2 0.33 10.5 0.9 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) AAA_28 PF13521.1 CEP14149.1 - 0.18 11.7 0.6 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 CEP14150.1 - 1.8e-17 63.7 0.1 2.9e-16 59.8 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP14150.1 - 6.1e-10 39.2 0.0 7.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CEP14150.1 - 5.2e-07 29.3 0.0 6.4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CEP14150.1 - 1.6e-05 24.6 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain FAM91_C PF14648.1 CEP14150.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 FAM91 C-terminus Glyco_hydro_9 PF00759.14 CEP14151.1 - 7.7e-82 275.5 5.5 7.1e-81 272.3 3.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 LIM PF00412.17 CEP14152.1 - 4.5e-50 167.5 42.9 1.6e-15 56.8 3.7 4.6 4 0 0 4 4 4 4 LIM domain RVT_1 PF00078.22 CEP14152.1 - 5.1e-11 42.3 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP14152.1 - 0.00073 19.7 1.1 0.0024 18.1 0.8 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_23 PF13384.1 CEP14152.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Nbl1_Borealin_N PF10444.4 CEP14152.1 - 0.24 10.7 1.7 11 5.4 0.0 3.1 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DDE_3 PF13358.1 CEP14155.1 - 1.1e-07 31.6 0.0 4.5e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP14155.1 - 0.008 15.8 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP14155.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.1 CEP14155.1 - 0.11 13.3 0.0 0.31 11.8 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain KOW PF00467.24 CEP14157.1 - 7.3e-10 38.1 3.7 2.1e-09 36.7 2.6 1.8 1 0 0 1 1 1 1 KOW motif TFIIF_alpha PF05793.7 CEP14157.1 - 1.6e-06 26.8 74.8 0.017 13.4 0.6 3.4 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1442 PF07279.6 CEP14157.1 - 0.13 11.3 1.4 0.22 10.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) PAS_3 PF08447.6 CEP14158.1 - 8.4e-11 41.8 0.0 1.8e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 CEP14158.1 - 3.3e-07 30.2 0.1 3.2e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 CEP14158.1 - 9.6e-07 29.1 0.0 0.031 14.6 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 CEP14158.1 - 2.7e-06 27.1 0.0 0.012 15.3 0.0 2.3 2 0 0 2 2 2 2 PAS fold DUF1749 PF08538.5 CEP14159.1 - 4.7e-60 203.0 0.1 6.2e-60 202.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CEP14159.1 - 2e-07 31.1 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP14159.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CEP14159.1 - 0.021 14.1 0.0 0.052 12.8 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 CEP14159.1 - 0.035 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 CEP14159.1 - 0.04 13.3 0.4 1.1 8.6 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF423 PF04241.10 CEP14160.1 - 3.4e-13 49.3 0.1 4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Pkinase PF00069.20 CEP14161.1 - 8e-71 238.2 0.0 1.1e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14161.1 - 2.9e-28 98.6 0.1 2.4e-27 95.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14161.1 - 1.2e-09 37.6 0.9 0.024 13.6 0.0 3.1 2 1 0 3 3 3 3 Kinase-like APH PF01636.18 CEP14161.1 - 0.0024 17.6 0.0 0.48 10.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CEP14161.1 - 0.044 13.1 0.2 0.89 8.8 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CEP14161.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WASH-7_C PF14746.1 CEP14163.1 - 0.054 13.1 0.2 0.081 12.5 0.2 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal LPP PF04728.8 CEP14163.1 - 0.06 13.1 4.1 1.7 8.5 0.1 2.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DDE_3 PF13358.1 CEP14164.1 - 5.2e-12 45.7 0.0 8.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP14164.1 - 5.3e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.1 CEP14164.1 - 7.5e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP14164.1 - 0.0007 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP14164.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.3 CEP14164.1 - 0.039 13.6 1.1 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Tc3 transposase TrmB PF01978.14 CEP14164.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Cactin_mid PF10312.4 CEP14165.1 - 0.0013 18.0 0.6 0.0014 17.9 0.4 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin DUF2098 PF09871.4 CEP14165.1 - 4.1 7.4 6.2 6.6 6.7 4.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) PIF1 PF05970.9 CEP14166.1 - 2.2e-14 53.2 0.0 2.7e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase GATA PF00320.22 CEP14167.1 - 3.9e-11 42.0 15.0 4.8e-10 38.6 2.4 2.6 2 0 0 2 2 2 2 GATA zinc finger 120_Rick_ant PF12574.3 CEP14167.1 - 0.0089 15.1 2.1 0.015 14.3 1.5 1.5 1 1 0 1 1 1 1 120 KDa Rickettsia surface antigen TF_Zn_Ribbon PF08271.7 CEP14167.1 - 2.2 7.6 9.8 0.36 10.1 0.9 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 CEP14167.1 - 6 6.7 19.8 0.3 10.9 5.1 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 CEP14167.1 - 6.2 6.1 8.0 19 4.6 1.3 3.1 2 1 1 3 3 3 0 zinc-ribbon domain Ctf8 PF09696.5 CEP14168.1 - 4.5e-18 65.1 0.0 6.3e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Ctf8 FeThRed_A PF02941.10 CEP14168.1 - 0.0029 17.4 0.4 0.0091 15.9 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin thioredoxin reductase variable alpha chain Vps54 PF07928.7 CEP14169.1 - 5.4e-49 165.7 2.4 5.4e-49 165.7 1.6 2.1 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 CEP14169.1 - 1.8e-11 43.4 2.3 6.4e-11 41.6 0.6 2.6 1 1 1 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) PSP1 PF04468.7 CEP14170.1 - 1.4e-33 114.7 1.7 1.4e-33 114.7 1.2 2.2 2 0 0 2 2 2 1 PSP1 C-terminal conserved region SIR2 PF02146.12 CEP14171.1 - 3.8e-31 108.1 0.0 4.9e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Lar_restr_allev PF14354.1 CEP14171.1 - 0.13 12.6 0.0 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar JmjC PF02373.17 CEP14172.1 - 2.5e-41 140.5 0.7 9.3e-41 138.6 0.5 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.6 CEP14172.1 - 3e-27 95.4 9.0 6.1e-26 91.1 2.9 2.4 2 0 0 2 2 2 2 PLU-1-like protein ARID PF01388.16 CEP14172.1 - 1.2e-21 76.3 0.1 3e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 CEP14172.1 - 5.9e-19 67.5 21.1 7.6e-13 47.9 4.2 3.2 4 0 0 4 4 4 2 PHD-finger JmjN PF02375.12 CEP14172.1 - 2e-17 62.3 3.5 5.3e-17 61.0 2.4 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 CEP14172.1 - 3.5e-11 42.9 12.7 3.5e-11 42.9 8.8 2.9 3 0 0 3 3 3 1 C5HC2 zinc finger zf-PHD-like PF15446.1 CEP14172.1 - 0.0098 15.2 10.7 0.02 14.1 1.0 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain Ndufs5 PF10200.4 CEP14172.1 - 0.083 12.8 3.1 0.39 10.7 0.4 3.0 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa E2F_TDP PF02319.15 CEP14173.1 - 3.5e-24 84.1 0.2 9.3e-24 82.7 0.2 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain EAF PF09816.4 CEP14173.1 - 0.0027 17.6 1.7 0.0057 16.6 0.2 2.2 2 1 0 2 2 2 1 RNA polymerase II transcription elongation factor TrmB PF01978.14 CEP14173.1 - 0.011 15.4 0.1 0.41 10.3 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB ARS2 PF04959.8 CEP14173.1 - 0.016 15.3 0.2 0.016 15.3 0.1 1.7 2 0 0 2 2 2 0 Arsenite-resistance protein 2 NEAT PF05031.7 CEP14173.1 - 0.033 14.1 1.5 0.064 13.2 1.0 1.5 1 0 0 1 1 1 0 Iron Transport-associated domain IncA PF04156.9 CEP14173.1 - 0.074 12.6 2.2 0.27 10.8 0.3 2.2 2 1 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 CEP14173.1 - 1.8 8.5 5.9 0.21 11.5 0.5 2.3 3 0 0 3 3 3 0 bZIP transcription factor RCC1 PF00415.13 CEP14175.1 - 1.5e-42 143.5 12.9 1.1e-08 35.1 0.0 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEP14175.1 - 9e-28 95.2 23.8 2.9e-06 26.7 0.0 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Peptidase_M49 PF03571.10 CEP14176.1 - 9.6e-06 23.9 0.2 0.00018 19.7 0.1 2.1 1 1 1 2 2 2 2 Peptidase family M49 ALS_ss_C PF10369.4 CEP14176.1 - 0.043 13.5 0.0 9.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Small subunit of acetolactate synthase PilJ PF13675.1 CEP14177.1 - 0.0074 16.5 0.5 0.017 15.4 0.3 1.7 1 1 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term Potyvirid-P3 PF13608.1 CEP14177.1 - 0.044 12.8 2.2 0.072 12.2 1.5 1.3 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein IncA PF04156.9 CEP14177.1 - 1.9 8.0 4.7 2.9 7.4 3.2 1.4 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 CEP14178.1 - 4.9e-78 261.8 0.0 6.6e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14178.1 - 8.8e-39 133.1 0.0 1.2e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14178.1 - 7.5e-07 28.3 0.0 0.00067 18.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CEP14178.1 - 1.3e-05 25.0 0.1 0.14 11.8 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CEP14178.1 - 1.7e-05 24.2 1.6 0.00014 21.2 0.0 2.2 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 CEP14178.1 - 0.00026 20.1 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CEP14178.1 - 0.002 17.5 0.1 0.022 14.0 0.0 2.3 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CEP14178.1 - 0.015 14.1 0.6 0.015 14.1 0.4 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Mito_carr PF00153.22 CEP14179.1 - 4.4e-65 215.4 6.0 6.7e-22 77.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Xpo1 PF08389.7 CEP14180.1 - 8.5e-05 22.4 0.7 0.0016 18.3 0.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 CEP14180.1 - 0.0012 18.7 0.0 0.41 10.8 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat TPR_1 PF00515.23 CEP14181.1 - 1e-53 176.8 36.5 3.7e-08 32.6 0.0 10.7 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 CEP14181.1 - 3.1e-48 157.8 30.6 3.5e-06 26.5 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 CEP14181.1 - 3.4e-46 154.7 29.1 2.3e-11 43.1 0.5 6.8 2 2 5 8 8 8 8 TPR repeat TPR_16 PF13432.1 CEP14181.1 - 2e-33 114.2 14.3 1.9e-07 31.5 0.0 6.8 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 CEP14181.1 - 4e-33 110.7 30.2 3.8e-05 23.1 0.0 9.6 7 1 2 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 CEP14181.1 - 2.1e-30 104.4 24.8 4.3e-06 26.5 1.3 6.5 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 CEP14181.1 - 3.7e-28 95.4 15.3 0.00051 20.4 0.0 9.5 3 2 7 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.1 CEP14181.1 - 6.4e-27 91.4 24.6 0.00046 20.1 0.1 10.9 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 CEP14181.1 - 1.2e-21 74.7 20.2 0.011 15.5 0.1 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 CEP14181.1 - 1.3e-21 76.7 18.5 1.5e-05 25.1 0.5 6.7 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 CEP14181.1 - 3.3e-19 67.9 26.1 0.001 19.3 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 CEP14181.1 - 8.9e-18 63.9 14.3 0.00019 21.2 0.2 6.4 3 2 4 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 CEP14181.1 - 1.7e-11 44.1 21.7 1.4e-06 28.3 2.3 4.6 3 2 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CEP14181.1 - 2.1e-09 36.8 16.0 0.0059 15.7 1.1 4.8 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 CEP14181.1 - 0.0003 20.8 0.2 2.5 8.2 0.0 4.6 3 2 2 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 CEP14181.1 - 0.0012 18.3 7.9 0.39 10.1 1.4 3.2 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.1 CEP14181.1 - 0.0022 17.1 19.0 0.63 9.1 1.8 4.7 2 2 2 4 4 4 2 Soluble NSF attachment protein, SNAP ChAPs PF09295.5 CEP14181.1 - 0.043 12.5 5.0 2.6 6.7 0.7 2.8 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF1824 PF08854.5 CEP14181.1 - 0.12 12.0 0.6 0.6 9.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) TPR_10 PF13374.1 CEP14181.1 - 0.18 11.7 0.0 0.18 11.7 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat BTAD PF03704.12 CEP14181.1 - 0.68 10.2 11.3 22 5.3 0.0 3.4 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_21 PF09976.4 CEP14181.1 - 1.7 8.5 21.7 4.3 7.2 0.0 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 CEP14181.1 - 3.3 7.6 23.7 2.6 7.9 0.3 6.1 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain DUF1751 PF08551.5 CEP14182.1 - 3.7e-26 91.3 2.9 3.7e-26 91.3 2.0 1.5 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 CEP14182.1 - 4e-07 30.1 2.1 6.9e-07 29.3 1.4 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1453 PF07301.6 CEP14182.1 - 0.02 14.7 0.6 0.031 14.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1453) Polysacc_synt_C PF14667.1 CEP14182.1 - 0.13 12.0 6.9 0.28 10.9 1.1 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain PPR_2 PF13041.1 CEP14183.1 - 6.8e-13 48.3 12.6 9.5e-05 22.3 0.1 8.2 5 3 4 9 9 9 4 PPR repeat family PPR_3 PF13812.1 CEP14183.1 - 9.1e-12 44.2 6.7 0.64 10.4 0.0 9.9 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 CEP14183.1 - 4.3e-07 29.4 1.4 1 9.4 0.1 7.3 8 0 0 8 8 8 1 PPR repeat TPR_19 PF14559.1 CEP14183.1 - 2e-05 24.8 0.1 0.36 11.1 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Corona_M PF01635.13 CEP14183.1 - 0.0084 15.0 0.0 0.056 12.4 0.0 2.1 2 0 0 2 2 2 1 Coronavirus M matrix/glycoprotein ATP13 PF12921.2 CEP14183.1 - 0.012 14.9 1.7 0.39 10.0 0.0 3.9 4 1 0 4 4 4 0 Mitochondrial ATPase expression PPR_1 PF12854.2 CEP14183.1 - 0.018 14.5 0.7 5.4 6.5 0.0 4.4 5 0 0 5 5 5 0 PPR repeat MnhB PF04039.8 CEP14183.1 - 0.21 11.6 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter ADH_N PF08240.7 CEP14185.1 - 2.2e-20 72.4 3.7 2.2e-20 72.4 2.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP14185.1 - 3.8e-19 68.5 0.0 5.4e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEP14185.1 - 0.00077 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 CEP14185.1 - 0.0011 19.8 0.0 0.0019 19.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IncA PF04156.9 CEP14186.1 - 0.0011 18.5 3.7 0.0011 18.5 2.5 2.3 2 0 0 2 2 2 1 IncA protein ATG16 PF08614.6 CEP14186.1 - 0.0029 17.4 5.5 0.0029 17.4 3.8 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.1 CEP14186.1 - 0.0092 15.1 6.9 0.0092 15.1 4.8 2.3 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 CEP14186.1 - 0.011 14.6 19.2 0.039 12.8 2.9 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CEP14186.1 - 0.054 12.5 19.2 0.3 10.0 4.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 CEP14186.1 - 0.3 11.4 22.9 0.4 11.0 1.9 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF972) DUF1843 PF08898.5 CEP14186.1 - 1.6 8.8 4.9 1.2 9.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) ADIP PF11559.3 CEP14186.1 - 7 6.5 25.8 1.6 8.5 3.7 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TPD52 PF04201.10 CEP14186.1 - 9.9 5.8 9.6 0.38 10.4 1.5 2.2 2 0 0 2 2 2 0 Tumour protein D52 family EF-hand_4 PF12763.2 CEP14187.1 - 3.8e-26 90.8 0.0 1.9e-14 53.2 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand RhoGEF PF00621.15 CEP14187.1 - 2.7e-24 86.0 0.5 7.5e-24 84.5 0.3 1.8 1 0 0 1 1 1 1 RhoGEF domain WH2 PF02205.15 CEP14187.1 - 4.8e-10 38.7 2.0 6.1e-10 38.3 0.2 2.2 2 0 0 2 2 2 1 WH2 motif CNH PF00780.17 CEP14187.1 - 7.8e-10 38.6 0.0 3.3e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 CNH domain EF-hand_7 PF13499.1 CEP14187.1 - 0.0043 17.1 0.0 0.02 15.0 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain pair PH_5 PF15405.1 CEP14187.1 - 0.0095 15.8 0.0 0.039 13.9 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain SpecificRecomb PF10136.4 CEP14187.1 - 0.04 11.9 0.2 0.082 10.9 0.1 1.4 1 0 0 1 1 1 0 Site-specific recombinase Polysacc_deac_1 PF01522.16 CEP14189.1 - 1.4e-29 102.2 0.0 2e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP14189.1 - 2.6e-07 29.8 0.0 4.7e-07 29.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.16 CEP14190.1 - 2.5e-26 91.7 0.0 3.3e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP14190.1 - 1.4e-06 27.4 0.0 3.2e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.4 CEP14190.1 - 0.0077 15.6 0.2 0.013 14.9 0.1 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF4578 PF15147.1 CEP14190.1 - 0.075 13.4 0.4 16 5.8 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4578) HLH PF00010.21 CEP14192.1 - 4.4e-13 48.6 1.6 1.2e-12 47.2 1.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1528 PF07515.6 CEP14192.1 - 7.2 6.6 10.1 2.7 8.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) DUF3455 PF11937.3 CEP14194.1 - 0.12 12.2 0.1 0.56 10.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3455) NAD_binding_10 PF13460.1 CEP14195.1 - 6e-17 62.2 0.0 7.6e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEP14195.1 - 0.00029 20.1 0.1 0.00051 19.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 CEP14195.1 - 0.028 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 CEP14195.1 - 0.058 12.0 0.1 0.076 11.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family cobW PF02492.14 CEP14195.1 - 0.066 12.6 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsbU_N PF08673.5 CEP14195.1 - 0.088 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Epimerase PF01370.16 CEP14195.1 - 0.095 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Trypsin_2 PF13365.1 CEP14196.1 - 1e-09 38.3 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CEP14196.1 - 1.6e-07 31.1 0.9 6.9e-07 29.0 0.6 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 CEP14196.1 - 0.075 12.4 0.4 0.28 10.5 0.1 2.0 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease DUF240 PF03086.9 CEP14197.1 - 0.017 14.7 0.0 0.05 13.2 0.0 1.8 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 GSHPx PF00255.14 CEP14198.1 - 0.11 11.8 0.6 0.85 9.0 0.0 2.0 2 0 0 2 2 2 0 Glutathione peroxidase Malic_M PF03949.10 CEP14199.1 - 6.4e-84 281.4 0.0 1.1e-83 280.7 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CEP14199.1 - 3.6e-72 241.7 0.0 7e-72 240.8 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Aa_trans PF01490.13 CEP14200.1 - 7.6e-77 258.5 30.0 9.3e-77 258.2 20.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tim54 PF11711.3 CEP14201.1 - 4.4e-55 186.8 1.5 8.4e-53 179.3 1.1 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 HSP70 PF00012.15 CEP14201.1 - 0.0024 15.8 0.7 0.0068 14.3 0.1 1.7 1 1 1 2 2 2 1 Hsp70 protein Pkinase PF00069.20 CEP14202.1 - 2.2e-60 203.9 0.0 4e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14202.1 - 2e-33 115.5 0.0 4.6e-33 114.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DcpS_C PF11969.3 CEP14202.1 - 1.1e-23 83.6 0.4 6.9e-23 81.0 0.1 2.2 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CEP14202.1 - 2.2e-11 44.1 0.4 7.8e-11 42.3 0.3 2.0 1 0 0 1 1 1 1 HIT domain 4F5 PF04419.9 CEP14202.1 - 6.6e-05 23.5 11.2 0.00018 22.1 7.8 1.8 1 0 0 1 1 1 1 4F5 protein family Kinase-like PF14531.1 CEP14202.1 - 0.00019 20.4 0.8 0.079 11.9 0.0 3.0 2 1 1 3 3 3 2 Kinase-like RIO1 PF01163.17 CEP14202.1 - 0.015 14.6 0.2 0.047 13.0 0.1 1.8 1 0 0 1 1 1 0 RIO1 family zf-C2H2_4 PF13894.1 CEP14202.1 - 0.15 12.4 0.3 1.5 9.3 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger APH PF01636.18 CEP14202.1 - 0.21 11.3 0.0 0.67 9.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family NLE PF08154.7 CEP14203.1 - 0.064 13.2 0.1 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 NLE (NUC135) domain Retrotrans_gag PF03732.12 CEP14204.1 - 1.2e-05 25.3 0.7 4.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CEP14204.1 - 3e-05 24.4 0.0 6.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP14204.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CEP14204.1 - 0.00023 21.0 0.4 0.00068 19.5 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 CEP14204.1 - 0.0015 17.8 0.0 0.0036 16.6 0.0 1.6 1 0 0 1 1 1 1 Ty3 transposon peptidase RP-C_C PF11800.3 CEP14204.1 - 1.4 8.5 8.2 1.2 8.7 1.7 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Helitron_like_N PF14214.1 CEP14206.1 - 3.9e-11 43.0 0.4 4.3e-11 42.8 0.3 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phe_ZIP PF08916.6 CEP14206.1 - 0.019 15.2 0.5 0.032 14.5 0.3 1.4 1 0 0 1 1 1 0 Phenylalanine zipper TauD PF02668.11 CEP14208.1 - 5.8e-41 140.8 0.3 1.3e-40 139.7 0.1 1.6 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CEP14208.1 - 1.1e-09 38.6 0.1 4.3e-09 36.6 0.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.5 CEP14208.1 - 0.0058 15.5 0.0 0.59 8.9 0.0 2.3 2 0 0 2 2 2 2 CsiD 2OG-FeII_Oxy_3 PF13640.1 CEP14208.1 - 0.047 14.1 0.0 0.36 11.3 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PP-binding PF00550.20 CEP14210.1 - 0.044 14.0 0.2 0.062 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphopantetheine attachment site Copper-fist PF00649.13 CEP14212.1 - 6.1e-10 38.1 0.8 1.7e-09 36.6 0.6 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Arg_repressor PF01316.16 CEP14212.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain SPX PF03105.14 CEP14213.1 - 1e-41 143.5 0.0 2e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CEP14213.1 - 5.3e-27 94.8 34.2 7.4e-27 94.3 23.7 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CEP14213.1 - 2.7e-21 75.5 30.4 3.5e-14 52.1 13.2 2.3 1 1 1 2 2 2 2 Citrate transporter DUF3270 PF11674.3 CEP14213.1 - 3 7.9 6.2 22 5.1 4.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) ODV-E18 PF10717.4 CEP14214.1 - 0.034 13.5 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Gram_pos_anchor PF00746.16 CEP14214.1 - 7.2 6.5 5.8 19 5.2 4.0 1.7 1 0 0 1 1 1 0 Gram positive anchor Thaumatin PF00314.12 CEP14215.1 - 4.2e-46 157.1 16.3 3.6e-45 154.0 11.3 1.9 1 1 0 1 1 1 1 Thaumatin family DUF4402 PF14352.1 CEP14215.1 - 0.095 13.1 5.0 1.8 9.0 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4402) OrfB_Zn_ribbon PF07282.6 CEP14216.1 - 1.5e-10 40.5 0.1 3.4e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain NMD3 PF04981.8 CEP14216.1 - 0.099 11.7 0.2 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 NMD3 family bZIP_1 PF00170.16 CEP14217.1 - 1.9e-06 27.7 4.5 1.9e-06 27.7 3.1 3.2 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.10 CEP14217.1 - 0.00016 21.4 6.7 0.00016 21.4 4.6 4.1 3 1 2 5 5 5 2 Basic region leucine zipper DUF972 PF06156.8 CEP14217.1 - 0.0039 17.5 5.4 0.0039 17.5 3.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF972) Striatin PF08232.7 CEP14217.1 - 0.018 15.3 7.7 0.018 15.3 5.3 2.6 2 1 0 2 2 2 0 Striatin family HAP1_N PF04849.8 CEP14217.1 - 0.087 11.7 21.0 0.5 9.2 14.5 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Macoilin PF09726.4 CEP14217.1 - 1.4 7.1 19.4 3.7 5.7 13.5 1.6 1 1 0 1 1 1 0 Transmembrane protein MscS_TM PF12794.2 CEP14217.1 - 3.1 6.3 4.6 7 5.1 3.2 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 bZIP_Maf PF03131.12 CEP14217.1 - 3.5 7.9 33.4 0.28 11.4 6.7 3.3 2 1 1 3 3 3 0 bZIP Maf transcription factor PRP3 PF08572.5 CEP14217.1 - 9.2 5.5 21.5 0.99 8.7 0.8 3.0 2 1 0 3 3 3 0 pre-mRNA processing factor 3 (PRP3) RNase_HII PF01351.13 CEP14217.1 - 9.9 5.7 8.1 0.89 9.1 0.7 2.2 2 0 0 2 2 2 0 Ribonuclease HII PH PF00169.24 CEP14218.1 - 1.8e-18 66.6 0.3 1.8e-18 66.6 0.2 2.1 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.1 CEP14218.1 - 8.3e-14 50.9 0.1 8.3e-14 50.9 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain SAM_2 PF07647.12 CEP14218.1 - 1.9e-13 50.0 0.4 2e-11 43.5 0.0 2.6 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 CEP14218.1 - 3.9e-13 48.5 0.4 3.9e-13 48.5 0.3 2.5 3 0 0 3 3 2 1 SH3 domain SH3_2 PF07653.12 CEP14218.1 - 2.6e-10 39.6 0.2 5.6e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 CEP14218.1 - 1.3e-07 31.6 0.1 2.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 CEP14218.1 - 3.4e-05 24.0 8.0 0.00031 20.9 2.6 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain CH PF00307.26 CEP14218.1 - 8.4e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain SAM_PNT PF02198.11 CEP14218.1 - 0.0038 16.9 1.6 0.04 13.6 0.0 2.8 2 1 1 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain PH_8 PF15409.1 CEP14218.1 - 0.011 15.7 1.1 0.082 12.9 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain SDA1 PF05285.7 CEP14218.1 - 1.8 7.7 14.3 2.8 7.1 9.9 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.7 CEP14218.1 - 5 5.3 19.9 7.4 4.8 13.8 1.1 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.7 CEP14218.1 - 7.2 5.7 10.0 12 5.0 6.9 1.3 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 CEP14218.1 - 8.6 6.0 10.2 19 4.9 7.1 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.7 CEP14218.1 - 9.3 4.0 17.8 13 3.5 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2058 PF09831.4 CEP14220.1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) NIR_SIR PF01077.17 CEP14220.1 - 0.044 13.1 0.1 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Kinesin PF00225.18 CEP14221.1 - 1.2e-91 306.9 0.3 1.2e-91 306.9 0.2 2.3 3 0 0 3 3 3 1 Kinesin motor domain DUF4050 PF13259.1 CEP14221.1 - 0.028 14.3 0.5 0.11 12.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Speriolin_N PF15058.1 CEP14221.1 - 1.1 9.1 5.0 0.33 10.8 0.2 2.1 2 0 0 2 2 2 0 Speriolin N terminus V_ATPase_I PF01496.14 CEP14221.1 - 5 4.8 19.8 2.7 5.7 1.8 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DER1 PF04511.10 CEP14222.1 - 9.5e-42 142.7 5.7 1.1e-41 142.5 4.0 1.0 1 0 0 1 1 1 1 Der1-like family TMEM171 PF15471.1 CEP14222.1 - 0.069 11.9 0.2 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Cytochrom_C1 PF02167.10 CEP14223.1 - 1.9e-87 292.5 0.0 2.3e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CEP14223.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CEP14223.1 - 0.021 15.6 0.4 0.072 13.9 0.3 2.1 1 1 0 1 1 1 0 Cytochrome c PIP5K PF01504.13 CEP14224.1 - 2.3e-81 272.6 0.8 3.6e-81 272.0 0.5 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Helitron_like_N PF14214.1 CEP14226.1 - 5.3e-08 32.8 0.0 9.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Rep_1 PF01446.12 CEP14226.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Replication protein GFA PF04828.9 CEP14228.1 - 2.4e-13 49.8 0.1 2.4e-13 49.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 CEP14228.1 - 0.018 14.6 4.4 0.024 14.3 0.0 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Peptidase_M28 PF04389.12 CEP14229.1 - 8.1e-32 110.3 0.3 1.4e-31 109.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M28 Acyl-CoA_dh_N PF02771.11 CEP14230.1 - 3.6e-37 127.4 0.0 5.1e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CEP14230.1 - 1.9e-19 68.9 0.0 3.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CEP14230.1 - 0.096 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CEP14231.1 - 1.4e-42 145.2 0.1 1.7e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CEP14231.1 - 7.5e-15 55.3 0.0 9.8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SIR2 PF02146.12 CEP14233.1 - 1.9e-35 122.2 0.0 3e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CEP14233.1 - 0.0053 16.5 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain RRN7 PF11781.3 CEP14233.1 - 0.15 11.6 1.5 42 3.7 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DDE_3 PF13358.1 CEP14235.1 - 6.9e-11 42.0 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 CEP14235.1 - 7.2e-07 28.6 0.0 1.9e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP14235.1 - 5.7e-06 26.2 0.9 1.4e-05 24.9 0.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP14235.1 - 8e-05 22.7 0.1 0.00016 21.7 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix CENP-B_N PF04218.8 CEP14235.1 - 0.00018 20.8 0.0 0.00041 19.7 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.1 CEP14235.1 - 0.00018 22.2 0.4 0.0013 19.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 CEP14235.1 - 0.0037 16.8 0.1 0.013 15.1 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain FeoC PF09012.5 CEP14235.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_3 PF01381.17 CEP14235.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_24 PF13412.1 CEP14235.1 - 0.077 12.3 0.1 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.1 CEP14235.1 - 0.081 12.1 0.0 0.22 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 CEP14235.1 - 0.096 12.9 0.3 0.34 11.2 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Yae1_N PF09811.4 CEP14237.1 - 9.1e-12 44.3 2.6 1.3e-11 43.8 1.8 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Strep_SA_rep PF06696.6 CEP14237.1 - 0.0039 16.9 1.9 0.0077 15.9 1.3 1.5 1 0 0 1 1 1 1 Streptococcal surface antigen repeat LRR_4 PF12799.2 CEP14238.1 - 4e-27 93.3 24.7 6.5e-07 28.8 1.1 6.4 4 2 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP14238.1 - 5.1e-27 93.4 20.9 3e-09 36.5 2.5 4.7 3 1 0 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CEP14238.1 - 2.7e-20 69.2 24.8 0.01 15.7 0.3 9.9 10 0 0 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 CEP14238.1 - 6.7e-10 37.5 26.7 0.28 11.5 0.3 10.4 11 1 1 12 12 12 4 Leucine rich repeat LRR_6 PF13516.1 CEP14238.1 - 4.5e-07 29.2 26.4 4.2 7.7 0.1 9.1 8 1 1 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 CEP14238.1 - 0.084 12.4 6.5 4.7 6.7 0.2 3.1 1 1 1 3 3 3 0 Leucine-rich repeat AA_permease_N PF08403.5 CEP14238.1 - 0.084 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal Flavin_Reduct PF01613.13 CEP14239.1 - 2.9e-36 124.6 0.1 6.7e-36 123.4 0.0 1.7 1 0 0 1 1 1 1 Flavin reductase like domain Arrestin_C PF02752.17 CEP14239.1 - 6.9e-11 42.4 1.3 6.2e-08 32.8 0.6 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP14239.1 - 2.2e-08 34.0 0.1 2.5e-07 30.6 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Cyclin PF08613.6 CEP14240.1 - 2e-18 67.2 1.0 2.9e-18 66.7 0.7 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP14240.1 - 0.00016 21.2 0.5 0.00026 20.5 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TIG PF01833.19 CEP14241.1 - 3.6e-13 49.3 3.8 1.1e-12 47.7 0.1 3.0 3 0 0 3 3 3 1 IPT/TIG domain Ank PF00023.25 CEP14241.1 - 5.5e-09 35.3 1.5 0.00019 21.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CEP14241.1 - 1.6e-08 34.7 1.8 3.2e-08 33.7 1.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP14241.1 - 3.6e-06 27.3 0.6 7.9e-06 26.2 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP14241.1 - 4.6e-05 23.2 1.8 0.09 13.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CEP14241.1 - 0.0038 17.4 1.8 0.098 12.9 0.0 2.7 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Syja_N PF02383.13 CEP14242.1 - 8.1e-94 313.9 0.1 1.1e-93 313.5 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain Fringe PF02434.11 CEP14242.1 - 0.056 12.6 0.3 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Fringe-like DUF3043 PF11241.3 CEP14242.1 - 0.27 10.8 2.6 2.1 7.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) NAD_binding_10 PF13460.1 CEP14243.1 - 0.0019 18.2 0.2 0.021 14.8 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding GHMP_kinases_N PF00288.21 CEP14243.1 - 0.034 14.2 0.2 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain Glyco_transf_15 PF01793.11 CEP14243.1 - 0.28 10.0 3.9 0.12 11.3 1.0 1.6 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase RCC1 PF00415.13 CEP14245.1 - 5e-32 109.8 2.3 9.7e-09 35.3 0.1 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CEP14245.1 - 9.8e-18 64.1 2.3 4e-07 29.9 0.0 3.8 2 2 1 3 3 3 2 BTB/POZ domain Ank_4 PF13637.1 CEP14245.1 - 1.4e-15 57.3 1.8 9.4e-13 48.3 0.2 3.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEP14245.1 - 7.7e-12 45.3 0.0 3e-11 43.4 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEP14245.1 - 4.1e-11 42.1 0.1 0.00015 21.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat RCC1_2 PF13540.1 CEP14245.1 - 5.7e-10 38.5 3.2 4.4e-08 32.5 0.0 3.4 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 CEP14245.1 - 7.7e-10 38.7 0.1 1.9e-05 24.7 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP14245.1 - 2.8e-09 36.3 0.4 0.006 16.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Acetyltransf_1 PF00583.19 CEP14246.1 - 1.3e-10 41.1 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP14246.1 - 4.9e-09 36.2 0.0 7.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP14246.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP14246.1 - 0.00019 21.1 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CEP14246.1 - 0.045 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PRP1_N PF06424.7 CEP14248.1 - 0.035 14.4 2.6 0.044 14.1 0.0 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal tRNA-synt_1b PF00579.20 CEP14249.1 - 7.4e-71 238.6 0.0 9.9e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Exo_endo_phos PF03372.18 CEP14250.1 - 4.6e-14 52.9 0.7 6.9e-14 52.3 0.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LETM1 PF07766.8 CEP14250.1 - 0.12 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 LETM1-like protein ALAD PF00490.16 CEP14251.1 - 6e-124 413.1 0.0 6.6e-124 413.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PEP_mutase PF13714.1 CEP14251.1 - 0.018 14.2 0.3 2.5 7.2 0.0 2.3 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Amidohydro_2 PF04909.9 CEP14251.1 - 0.026 14.0 0.1 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Hemerythrin PF01814.18 CEP14251.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Phage_int_SAM_4 PF13495.1 CEP14252.1 - 0.01 16.1 0.0 0.59 10.5 0.0 2.5 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 CEP14252.1 - 0.013 15.6 0.2 0.036 14.2 0.1 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.17 CEP14252.1 - 0.081 12.5 0.1 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Phage integrase family SLS PF14611.1 CEP14253.1 - 0.037 13.4 0.1 0.076 12.4 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Thiolase_N PF00108.18 CEP14254.1 - 2.6e-79 265.9 1.9 5.3e-79 264.9 0.7 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEP14254.1 - 6.1e-46 154.8 0.0 1.2e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Guanylate_kin PF00625.16 CEP14255.1 - 3.9e-63 212.1 0.0 4.4e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 CEP14255.1 - 8.2e-09 35.4 0.0 3.4e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP14255.1 - 9.3e-07 29.2 0.1 4.2e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP14255.1 - 1.1e-06 28.7 0.0 2.9e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP14255.1 - 1.4e-06 29.1 0.1 6.5e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP14255.1 - 3.7e-05 23.7 0.1 7.6e-05 22.7 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.22 CEP14255.1 - 8.8e-05 22.8 0.0 0.00015 22.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 CEP14255.1 - 0.00034 20.1 0.7 0.00048 19.6 0.1 1.6 1 1 1 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 CEP14255.1 - 0.00052 19.7 0.2 0.00056 19.6 0.1 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 CEP14255.1 - 0.00065 19.6 0.1 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 CEP14255.1 - 0.00066 20.1 0.1 0.0016 18.9 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CEP14255.1 - 0.00071 18.8 0.0 0.00084 18.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEP14255.1 - 0.00086 18.7 0.3 0.0022 17.4 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 CEP14255.1 - 0.0018 17.6 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase MMR_HSR1 PF01926.18 CEP14255.1 - 0.0023 17.8 0.0 0.0037 17.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 CEP14255.1 - 0.0031 17.1 0.1 0.0064 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CEP14255.1 - 0.0035 17.0 0.1 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CEP14255.1 - 0.0061 16.9 0.1 0.0061 16.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEP14255.1 - 0.0076 16.4 0.1 0.012 15.7 0.0 1.6 1 1 0 1 1 1 1 RNA helicase cobW PF02492.14 CEP14255.1 - 0.012 15.0 0.1 0.056 12.8 0.0 2.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CEP14255.1 - 0.014 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 CEP14255.1 - 0.017 15.0 0.0 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 CEP14255.1 - 0.019 14.9 0.1 0.037 13.9 0.0 1.6 2 1 1 3 3 1 0 AAA domain NACHT PF05729.7 CEP14255.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 CEP14255.1 - 0.031 13.2 0.0 0.33 9.8 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 CEP14255.1 - 0.048 13.2 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ADK PF00406.17 CEP14255.1 - 0.053 13.4 0.9 34 4.2 0.0 3.0 2 1 1 3 3 3 0 Adenylate kinase Rad17 PF03215.10 CEP14255.1 - 0.07 11.8 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 CEP14255.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 CEP14255.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 CEP14255.1 - 0.095 12.2 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CEP14255.1 - 0.098 11.4 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Pox_A32 PF04665.7 CEP14255.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Dynamin_N PF00350.18 CEP14255.1 - 0.1 12.3 0.3 0.12 12.2 0.2 1.5 1 1 0 1 1 1 0 Dynamin family DUF87 PF01935.12 CEP14255.1 - 0.13 12.0 0.1 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Gtr1_RagA PF04670.7 CEP14255.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region CPT PF07931.7 CEP14255.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein WD40 PF00400.27 CEP14256.1 - 2e-46 154.2 16.9 2.7e-09 36.5 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP14256.1 - 4.6e-13 48.1 7.9 0.0014 16.9 0.1 5.1 2 1 3 5 5 5 5 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP14256.1 - 4.8e-08 32.6 1.0 1e-07 31.5 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP14256.1 - 8.1e-07 28.5 1.5 1.9e-06 27.3 1.1 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CEP14256.1 - 6.5e-06 25.7 1.5 0.015 14.7 0.2 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 CEP14256.1 - 0.0042 17.3 0.1 18 5.7 0.2 3.9 2 1 2 4 4 4 1 PQQ-like domain BBS2_Mid PF14783.1 CEP14256.1 - 0.037 13.7 0.1 5.5 6.8 0.0 3.5 3 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Daxx PF03344.10 CEP14257.1 - 0.036 12.5 0.0 0.037 12.5 0.0 1.0 1 0 0 1 1 1 0 Daxx Family Glyco_hydro_1 PF00232.13 CEP14257.1 - 0.088 10.9 0.1 0.094 10.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF3425 PF11905.3 CEP14258.1 - 2.7e-12 46.7 17.8 3.2e-12 46.5 5.7 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CEP14258.1 - 5.4e-09 35.8 4.9 1.2e-08 34.8 3.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP14258.1 - 0.0039 16.9 8.6 0.0068 16.2 5.3 1.9 1 1 0 1 1 1 1 Basic region leucine zipper DUF2205 PF10224.4 CEP14258.1 - 0.017 14.7 1.3 0.04 13.4 0.9 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DNA_pack_C PF02499.10 CEP14258.1 - 0.052 12.2 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus Glycos_transf_1 PF00534.15 CEP14259.1 - 6e-12 45.3 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CEP14259.1 - 3.8e-11 42.9 0.4 1.7e-10 40.8 0.3 2.1 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 CEP14259.1 - 5.1e-05 23.4 0.7 0.00012 22.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CEP14259.1 - 0.0013 18.8 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 PAS_11 PF14598.1 CEP14261.1 - 0.29 11.1 2.2 8.5 6.3 0.2 3.0 1 1 2 3 3 3 0 PAS domain Phage_integrase PF00589.17 CEP14262.1 - 7.1e-06 25.7 0.2 9.8e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family DDE_Tnp_4 PF13359.1 CEP14263.1 - 3.1e-21 75.6 0.0 9.7e-21 74.0 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP14263.1 - 0.066 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm29 PF15575.1 CEP14263.1 - 0.079 12.5 0.1 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 29 Ribosomal_L14 PF00238.14 CEP14265.1 - 3.5e-44 149.4 0.8 3.9e-44 149.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ACP_syn_III PF08545.5 CEP14265.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DnaJ-X PF14308.1 CEP14266.1 - 2.7e-50 170.4 0.2 2.7e-50 170.4 0.1 2.3 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 CEP14266.1 - 3.5e-24 84.3 1.6 8.6e-24 83.0 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4536 PF15055.1 CEP14266.1 - 0.28 11.2 0.8 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) E7 PF00527.13 CEP14266.1 - 7.8 6.7 6.8 39 4.4 0.1 3.5 2 1 1 3 3 3 0 E7 protein, Early protein RRP7 PF12923.2 CEP14267.1 - 2.2e-37 128.0 15.0 2.2e-37 128.0 10.4 3.2 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CEP14267.1 - 0.0078 15.8 0.0 0.26 10.9 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tox-PL PF15644.1 CEP14267.1 - 0.059 14.1 2.5 1.8 9.3 0.1 3.1 2 1 1 3 3 3 0 Papain fold toxin 1 Psb28 PF03912.9 CEP14267.1 - 0.17 11.8 5.5 0.47 10.4 1.1 2.6 2 0 0 2 2 2 0 Psb28 protein Usp PF00582.21 CEP14267.1 - 8.3 6.6 7.5 9.5 6.4 1.3 2.6 2 1 0 2 2 2 0 Universal stress protein family UDP-g_GGTase PF06427.6 CEP14268.1 - 1.6e-60 204.0 0.0 2.9e-60 203.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase MFS_1 PF07690.11 CEP14268.1 - 1.7e-12 46.7 36.4 2.1e-06 26.7 10.6 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3784 PF12650.2 CEP14268.1 - 1.2 9.0 8.5 0.051 13.5 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) F-box-like PF12937.2 CEP14269.1 - 6.1e-08 32.2 0.1 1.7e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP14269.1 - 0.012 15.2 3.0 0.012 15.2 0.2 2.4 2 0 0 2 2 2 0 F-box domain NAD_binding_10 PF13460.1 CEP14270.1 - 7.1e-13 48.9 0.0 8.9e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Lipase_GDSL PF00657.17 CEP14271.1 - 3.6e-21 76.0 0.2 4.3e-21 75.8 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP14271.1 - 1.5e-08 34.9 0.0 2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PQ-loop PF04193.9 CEP14272.1 - 6.2e-30 102.5 5.3 3.3e-17 61.7 1.2 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 CEP14272.1 - 0.0088 15.8 0.7 0.078 12.8 0.0 2.5 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Phosphonate-bd PF12974.2 CEP14272.1 - 0.17 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein RNase_T PF00929.19 CEP14273.1 - 9.9e-27 94.2 0.0 1.7e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease SAP PF02037.22 CEP14273.1 - 0.00074 18.9 0.1 0.0016 17.9 0.1 1.6 1 0 0 1 1 1 1 SAP domain AA_permease_2 PF13520.1 CEP14274.1 - 5.7e-66 222.8 35.0 7.2e-66 222.4 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP14274.1 - 3.5e-36 124.5 34.9 4.7e-36 124.1 24.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ank_2 PF12796.2 CEP14275.1 - 8.2e-26 90.1 0.0 1.1e-10 41.6 0.2 4.2 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEP14275.1 - 5.3e-23 79.6 0.1 0.00022 20.8 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 CEP14275.1 - 3.5e-17 60.7 1.5 0.0065 16.6 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CEP14275.1 - 1.6e-16 59.8 1.1 7.8e-06 25.9 0.2 5.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP14275.1 - 8.1e-16 58.0 0.2 2.4e-06 27.8 0.0 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Prefoldin_2 PF01920.15 CEP14276.1 - 1.4e-20 73.0 1.5 1.6e-20 72.8 1.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Myosin_tail_1 PF01576.14 CEP14276.1 - 0.019 12.7 3.8 0.82 7.3 0.5 2.0 2 0 0 2 2 2 0 Myosin tail Sec8_exocyst PF04048.9 CEP14276.1 - 0.068 12.8 1.3 0.16 11.5 0.2 1.8 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain FlxA PF14282.1 CEP14276.1 - 0.18 11.7 3.4 0.15 12.0 0.6 2.0 2 0 0 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.17 CEP14276.1 - 0.31 11.0 6.0 0.19 11.7 0.9 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 CEP14276.1 - 3.1 7.3 5.4 2.5 7.6 1.0 2.1 2 0 0 2 2 2 0 Septum formation initiator zf-AN1 PF01428.11 CEP14277.1 - 8.4e-11 41.5 15.2 1.3e-10 40.9 4.1 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Caudo_TAP PF02413.12 CEP14277.1 - 0.029 14.5 1.6 0.041 14.0 1.1 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein IBR PF01485.16 CEP14277.1 - 0.42 10.5 10.8 2.4 8.1 7.5 2.3 1 1 0 1 1 1 0 IBR domain Transp_Tc5_C PF04236.10 CEP14277.1 - 0.55 10.4 5.0 1.3 9.2 3.5 1.7 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain NinG PF05766.7 CEP14277.1 - 2.3 7.9 11.1 4.4 7.0 7.5 1.7 1 1 0 1 1 1 0 Bacteriophage Lambda NinG protein UPF0547 PF10571.4 CEP14277.1 - 5.2 6.8 7.6 2.8 7.7 1.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-Tim10_DDP PF02953.10 CEP14279.1 - 2e-22 78.2 1.5 5.9e-22 76.7 1.0 1.9 1 0 0 1 1 1 1 Tim10/DDP family zinc finger GTP_EFTU PF00009.22 CEP14281.1 - 9e-60 201.3 0.6 1.3e-59 200.7 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEP14281.1 - 4.8e-30 103.6 0.5 2.2e-29 101.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEP14281.1 - 4.6e-17 61.8 3.3 1.3e-16 60.4 2.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEP14281.1 - 2.3e-05 24.2 0.1 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CEP14281.1 - 0.0003 20.3 0.4 0.00081 18.9 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CEP14281.1 - 0.0026 18.2 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 CEP14281.1 - 0.011 15.1 0.7 0.018 14.4 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Alba PF01918.16 CEP14281.1 - 0.018 14.6 0.0 0.056 13.0 0.0 1.9 1 0 0 1 1 1 0 Alba PduV-EutP PF10662.4 CEP14281.1 - 0.025 14.0 0.2 5.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT PF02985.17 CEP14282.1 - 1.4e-13 49.6 9.8 0.02 14.9 0.1 7.9 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 CEP14282.1 - 5.2e-08 33.0 2.0 0.012 15.9 0.0 6.5 4 3 1 6 6 6 3 HEAT repeats Mannosyl_trans3 PF11051.3 CEP14283.1 - 2.6e-51 174.5 0.2 4.8e-51 173.7 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_15 PF01793.11 CEP14284.1 - 1.7e-82 277.0 15.1 2.1e-82 276.7 10.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.2 CEP14284.1 - 0.12 12.3 2.5 0.23 11.4 1.7 1.4 1 0 0 1 1 1 0 EGF domain zf-tcix PF14952.1 CEP14285.1 - 0.034 13.4 2.6 0.065 12.5 1.8 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding UPF0242 PF06785.6 CEP14285.1 - 0.27 9.8 1.0 0.32 9.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) Spc7 PF08317.6 CEP14287.1 - 0.00039 19.1 17.5 0.00067 18.4 12.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1423 PF07227.6 CEP14287.1 - 0.00089 18.0 11.1 0.0012 17.5 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) BLOC1_2 PF10046.4 CEP14287.1 - 0.00089 19.3 16.3 0.13 12.4 0.3 3.7 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4618 PF15397.1 CEP14287.1 - 0.0039 16.5 10.6 0.0039 16.5 7.4 2.6 1 1 2 3 3 3 1 Domain of unknown function (DUF4618) Reo_sigmaC PF04582.7 CEP14287.1 - 0.0056 15.9 2.8 0.0083 15.3 2.0 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Lip_prot_lig_C PF10437.4 CEP14287.1 - 0.047 13.3 1.2 7.4 6.3 0.0 3.8 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Apo-VLDL-II PF05418.6 CEP14287.1 - 0.083 13.0 0.5 0.22 11.7 0.2 1.8 1 1 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) PspA_IM30 PF04012.7 CEP14287.1 - 0.096 12.0 15.1 0.27 10.5 2.3 2.4 1 1 0 2 2 2 0 PspA/IM30 family Laminin_I PF06008.9 CEP14287.1 - 0.18 11.1 15.1 1.1 8.4 6.3 2.3 1 1 1 2 2 2 0 Laminin Domain I Atg14 PF10186.4 CEP14287.1 - 0.19 10.6 15.1 0.15 10.9 8.9 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 P4Ha_N PF08336.6 CEP14287.1 - 0.39 10.5 9.5 0.35 10.6 3.3 2.5 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_MLP1_2 PF07926.7 CEP14287.1 - 0.66 9.7 18.9 0.13 11.9 4.9 3.4 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 CEP14287.1 - 0.68 9.4 9.4 2.2 7.7 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF948 PF06103.6 CEP14287.1 - 1.3 8.9 13.1 0.41 10.5 1.9 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) XkdW PF09636.5 CEP14287.1 - 1.7 8.5 6.0 0.39 10.5 0.6 2.6 3 0 0 3 3 3 0 XkdW protein IncA PF04156.9 CEP14287.1 - 2.4 7.6 19.9 1.7e+02 1.7 13.7 2.4 1 1 0 1 1 1 0 IncA protein Prefoldin PF02996.12 CEP14287.1 - 3.6 7.2 17.7 11 5.7 2.4 3.8 2 2 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 CEP14287.1 - 4.1 7.2 15.7 3.4 7.5 3.9 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 CEP14287.1 - 4.2 7.8 14.0 3 8.2 2.4 3.7 1 1 1 3 3 3 0 SlyX APG6 PF04111.7 CEP14287.1 - 4.8 6.1 21.1 0.16 10.9 4.6 2.5 1 1 2 3 3 3 0 Autophagy protein Apg6 CR6_interact PF10147.4 CEP14287.1 - 5.2 6.3 11.8 0.048 12.9 0.9 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SPX PF03105.14 CEP14287.1 - 5.9 6.5 8.9 11 5.6 6.2 1.5 1 0 0 1 1 1 0 SPX domain Ras PF00071.17 CEP14288.1 - 3.6e-43 146.7 0.6 3.1e-22 78.6 0.1 2.5 2 0 0 2 2 2 2 Ras family RhoGEF PF00621.15 CEP14288.1 - 1.7e-30 106.2 0.7 3.3e-30 105.2 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 CEP14288.1 - 1.3e-22 80.2 1.4 3.7e-22 78.7 0.9 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain CRAL_TRIO PF00650.15 CEP14288.1 - 1e-13 51.0 0.7 1.4e-12 47.3 0.1 3.1 2 1 1 3 3 3 1 CRAL/TRIO domain PB1 PF00564.19 CEP14288.1 - 3.7e-13 48.9 0.1 2.4e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 PB1 domain Miro PF08477.8 CEP14288.1 - 1.2e-05 25.8 0.0 0.0042 17.5 0.0 3.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP14288.1 - 0.00053 19.2 0.1 0.006 15.8 0.1 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family SPAM PF02090.10 CEP14288.1 - 0.039 13.9 1.2 0.11 12.4 0.9 1.7 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein PLDc_2 PF13091.1 CEP14289.1 - 2.2e-13 50.0 0.0 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CEP14289.1 - 0.0024 17.6 1.6 0.21 11.4 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif OrfB_Zn_ribbon PF07282.6 CEP14290.1 - 0.027 14.1 0.1 0.3 10.7 0.0 2.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain ADK PF00406.17 CEP14291.1 - 2.3e-47 160.6 0.0 3.7e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CEP14291.1 - 1.5e-11 43.7 0.0 3.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CEP14291.1 - 1.9e-08 35.1 0.0 3.7e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP14291.1 - 5.1e-07 30.0 0.0 1.3e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CEP14291.1 - 0.00017 21.4 0.0 0.00061 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEP14291.1 - 0.0057 15.7 0.0 0.037 13.1 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin Leo1 PF04004.8 CEP14291.1 - 0.087 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Leo1-like protein DnaJ PF00226.26 CEP14292.1 - 1e-26 92.4 1.1 2.1e-26 91.4 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.4 CEP14292.1 - 1.4e-13 51.0 35.7 1.1e-06 28.4 7.8 3.4 1 1 3 4 4 4 4 Transmembrane Fragile-X-F protein Tmemb_9 PF05434.6 CEP14292.1 - 0.7 9.6 0.0 0.7 9.6 0.0 2.8 2 1 1 3 3 3 0 TMEM9 DUF912 PF06024.7 CEP14292.1 - 2.1 8.4 7.3 5.8 7.0 0.0 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Abhydrolase_9_N PF15420.1 CEP14292.1 - 2.7 7.7 9.4 0.04 13.6 0.5 2.1 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Peptidase_M18 PF02127.10 CEP14293.1 - 1.2e-164 547.9 0.1 1.5e-164 547.6 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CEP14293.1 - 1.1e-08 34.2 0.7 1.8e-06 26.9 0.1 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Aa_trans PF01490.13 CEP14294.1 - 3.4e-53 180.5 18.1 7.7e-32 110.2 7.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Med21 PF11221.3 CEP14294.1 - 3.3e-29 101.7 5.8 5.8e-29 100.9 4.0 1.4 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_permease PF03845.8 CEP14294.1 - 0.0029 16.3 0.5 0.0029 16.3 0.3 3.2 3 0 0 3 3 3 2 Spore germination protein CENP-Q PF13094.1 CEP14294.1 - 0.013 15.5 3.9 0.022 14.8 2.7 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit YebO PF13974.1 CEP14294.1 - 0.071 12.8 1.3 0.23 11.2 0.9 1.9 1 0 0 1 1 1 0 YebO-like protein DUF3278 PF11683.3 CEP14294.1 - 0.077 12.9 0.1 0.077 12.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Med9 PF07544.8 CEP14294.1 - 0.37 10.5 2.6 0.61 9.8 1.2 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF727 PF05303.7 CEP14295.1 - 1.1e-09 38.0 0.0 1.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF727) UPF0560 PF10577.4 CEP14295.1 - 0.0013 17.0 5.4 0.0016 16.7 3.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 Plasmodium_Vir PF05795.6 CEP14296.1 - 0.012 14.8 0.4 0.012 14.8 0.3 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SPARC_Ca_bdg PF10591.4 CEP14296.1 - 0.083 12.9 0.3 11 6.0 0.0 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ABC2_membrane PF01061.19 CEP14297.1 - 0.037 13.2 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 ABC-2 type transporter Transposase_21 PF02992.9 CEP14298.1 - 0.00045 19.3 0.0 0.00052 19.1 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Transposase_21 PF02992.9 CEP14301.1 - 5.4e-08 32.1 0.0 6.6e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Sulfolobus_pRN PF05584.6 CEP14302.1 - 0.048 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein DDE_3 PF13358.1 CEP14303.1 - 1.3e-15 57.3 0.0 2.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP14303.1 - 2.6e-09 37.0 0.1 1.5e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 CEP14303.1 - 5e-07 29.8 0.0 9.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP14303.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 CEP14303.1 - 0.093 12.4 0.0 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Cu-oxidase_2 PF07731.9 CEP14304.1 - 3.3e-14 52.5 12.7 1.1e-10 41.1 2.9 3.8 2 2 1 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CEP14304.1 - 2.2e-07 30.6 3.9 1.1e-05 25.1 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase MutS_V PF00488.16 CEP14305.1 - 2.6e-83 279.0 0.2 5e-83 278.0 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CEP14305.1 - 1.1e-40 139.6 0.1 2.8e-40 138.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CEP14305.1 - 5.1e-28 97.3 0.0 1e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CEP14305.1 - 6.9e-14 52.0 0.0 2.4e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CEP14305.1 - 8.4e-09 35.4 0.6 8.4e-09 35.4 0.5 2.4 2 0 0 2 2 2 1 MutS family domain IV RRM_1 PF00076.17 CEP14306.1 - 1.8e-19 69.1 0.0 3.6e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP14306.1 - 1.5e-12 47.3 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP14306.1 - 6e-10 38.8 0.0 1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TSLP PF15216.1 CEP14306.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Thymic stromal lymphopoietin Zip PF02535.17 CEP14306.1 - 0.1 11.5 3.2 0.12 11.3 2.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MIP-T3 PF10243.4 CEP14306.1 - 5.8 5.2 31.8 7.8 4.8 22.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HMG_box PF00505.14 CEP14307.1 - 5.8e-13 48.8 11.9 3.6e-07 30.3 0.9 3.1 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP14307.1 - 2.3e-11 43.8 5.1 1.5e-05 25.2 0.1 2.7 2 1 0 2 2 2 2 HMG-box domain Ofd1_CTDD PF10637.4 CEP14308.1 - 0.18 10.9 2.2 0.28 10.2 1.5 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term NifQ PF04891.7 CEP14309.1 - 2.3 8.3 4.6 5.8 7.0 0.2 2.7 1 1 2 3 3 3 0 NifQ ABC_membrane PF00664.18 CEP14310.1 - 1.1e-99 333.2 28.2 5.8e-52 176.7 10.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP14310.1 - 1.1e-67 226.4 6.7 4.2e-35 121.0 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 CEP14310.1 - 3.4e-12 46.0 10.2 1.1e-05 24.8 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEP14310.1 - 5.2e-12 46.3 0.0 0.0084 16.1 0.0 4.6 3 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 CEP14310.1 - 3.4e-09 35.8 1.9 0.00069 18.3 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 CEP14310.1 - 2.6e-08 34.0 4.4 0.0024 18.0 0.4 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CEP14310.1 - 3.6e-08 33.6 6.1 0.0019 18.2 0.6 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CEP14310.1 - 2.2e-07 30.2 1.9 0.0057 16.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CEP14310.1 - 6.8e-07 30.1 0.0 0.041 14.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 CEP14310.1 - 2.6e-06 26.7 0.1 0.068 12.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 CEP14310.1 - 2.2e-05 24.1 3.9 0.066 12.7 0.2 4.3 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CEP14310.1 - 6.3e-05 22.1 0.3 0.31 10.1 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_23 PF13476.1 CEP14310.1 - 0.0001 22.6 4.6 1 9.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 CEP14310.1 - 0.00017 21.7 5.3 0.37 10.9 0.8 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CEP14310.1 - 0.0002 21.2 0.0 0.78 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CEP14310.1 - 0.00024 20.8 1.6 0.17 11.5 0.1 3.1 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CEP14310.1 - 0.00026 21.3 0.0 1.6 9.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CEP14310.1 - 0.0003 20.6 3.5 0.73 9.7 0.3 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CEP14310.1 - 0.00061 19.6 0.0 1.6 8.6 0.0 4.3 3 1 1 4 4 4 1 AAA domain DUF815 PF05673.8 CEP14310.1 - 0.0021 17.0 0.0 0.2 10.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CEP14310.1 - 0.0025 17.7 0.1 2.1 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEP14310.1 - 0.0027 17.2 3.1 1.6 8.1 0.2 3.3 3 1 0 4 4 4 2 AAA-like domain SRP54 PF00448.17 CEP14310.1 - 0.0038 16.6 0.2 0.8 9.1 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 CEP14310.1 - 0.0056 16.8 0.2 4 7.6 0.0 3.6 4 0 0 4 4 3 1 RNA helicase Miro PF08477.8 CEP14310.1 - 0.0063 17.0 0.2 2.1 8.8 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein AAA_25 PF13481.1 CEP14310.1 - 0.011 15.1 0.3 9.4 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 CEP14310.1 - 0.011 14.3 3.5 2 7.0 1.0 2.8 2 1 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 CEP14310.1 - 0.012 14.3 0.0 0.16 10.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CEP14310.1 - 0.014 15.1 0.5 7 6.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PRK PF00485.13 CEP14310.1 - 0.014 14.9 0.0 4.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 CEP14310.1 - 0.016 15.1 0.6 8 6.4 0.3 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 CEP14310.1 - 0.086 11.9 0.0 4.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 CEP14310.1 - 0.098 12.4 8.1 0.2 11.4 0.0 3.4 4 0 0 4 4 3 0 Domain of unknown function DUF87 NACHT PF05729.7 CEP14310.1 - 0.13 11.9 1.7 8.7 5.9 0.0 3.1 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.13 CEP14310.1 - 0.17 11.3 1.2 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Peroxidase_2 PF01328.12 CEP14311.1 - 7.7e-15 54.3 0.1 1.4e-14 53.5 0.0 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 DUF4451 PF14616.1 CEP14312.1 - 0.37 10.5 2.4 0.36 10.5 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) MTHFR PF02219.12 CEP14313.1 - 1.3e-104 349.3 0.0 2.3e-104 348.5 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DnaJ PF00226.26 CEP14313.1 - 3.7e-20 71.4 0.0 9.1e-20 70.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain RRN3 PF05327.6 CEP14313.1 - 0.12 10.4 0.1 0.18 9.8 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HMG_box PF00505.14 CEP14314.1 - 3e-25 88.2 2.2 6.4e-25 87.2 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP14314.1 - 1.4e-17 63.7 3.6 4e-17 62.3 2.5 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CEP14314.1 - 0.00056 19.6 1.3 0.00056 19.6 0.9 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box 5 VPS28 PF03997.7 CEP14314.1 - 0.0099 15.5 1.0 0.018 14.6 0.1 1.8 2 0 0 2 2 2 1 VPS28 protein Fe_hyd_lg_C PF02906.9 CEP14314.1 - 0.039 13.2 0.8 0.053 12.7 0.5 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF1014 PF06244.7 CEP14314.1 - 5.6 7.2 11.6 28 4.9 7.3 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) HVSL PF09749.4 CEP14315.1 - 2.3e-38 131.5 4.2 1.2e-36 125.9 2.9 2.1 1 1 0 1 1 1 1 Uncharacterised conserved protein Amino_oxidase PF01593.19 CEP14315.1 - 0.052 12.6 0.2 0.067 12.2 0.1 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF3395 PF11875.3 CEP14316.1 - 7.9e-35 119.7 0.1 7.9e-35 119.7 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CEP14316.1 - 3.7e-18 65.0 1.0 3.7e-18 65.0 0.7 2.5 2 1 1 3 3 3 1 DnaJ domain KMP11 PF03037.11 CEP14316.1 - 5.5 7.6 8.7 0.67 10.5 0.4 2.7 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 Chitin_synth_2 PF03142.10 CEP14317.1 - 6e-47 160.2 0.1 9.7e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.23 CEP14317.1 - 0.00031 20.4 0.0 0.00078 19.1 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Chitin_synth_2 PF03142.10 CEP14318.1 - 1.8e-159 531.5 4.4 2.1e-159 531.3 3.1 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP14318.1 - 3.5e-10 39.9 5.5 1.4e-09 37.9 4.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP14318.1 - 1.1e-08 35.1 0.0 2e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Dabb PF07876.7 CEP14319.1 - 2.3e-21 76.0 0.2 2.5e-21 75.9 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain TFIIF_beta PF02270.10 CEP14320.1 - 2.6e-66 224.2 0.3 6.2e-43 147.5 0.0 2.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit DAD PF02109.11 CEP14320.1 - 1.4e-32 112.0 0.2 2.7e-32 111.1 0.1 1.4 1 0 0 1 1 1 1 DAD family BMFP PF04380.8 CEP14321.1 - 0.024 14.7 0.8 11 6.2 0.1 2.9 2 1 0 2 2 2 0 Membrane fusogenic activity NTNH_C PF08470.5 CEP14321.1 - 0.052 13.1 2.3 0.091 12.3 1.6 1.4 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal FlxA PF14282.1 CEP14321.1 - 1.1 9.2 7.0 0.98 9.3 0.1 3.3 3 0 0 3 3 3 0 FlxA-like protein zf-H2C2 PF09337.5 CEP14322.1 - 0.00057 19.2 1.7 0.00091 18.5 1.2 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Chromo PF00385.19 CEP14323.1 - 1.1e-09 37.7 0.8 2e-09 36.9 0.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP14323.1 - 0.0039 16.8 1.6 0.028 14.1 0.1 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain WD40 PF00400.27 CEP14324.1 - 1.8e-10 40.2 0.0 2.2e-07 30.4 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat CRT10 PF08728.5 CEP14324.1 - 6.8e-10 37.6 9.2 1.1e-05 23.6 0.6 3.0 2 2 0 2 2 2 2 CRT10 Apc4_WD40 PF12894.2 CEP14324.1 - 0.085 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M18 PF02127.10 CEP14325.1 - 3e-167 556.5 0.0 4.1e-167 556.0 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) RFX_DNA_binding PF02257.10 CEP14325.1 - 8.1e-32 109.2 0.2 2.2e-31 107.8 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Peptidase_M42 PF05343.9 CEP14325.1 - 1.6e-05 23.8 0.1 0.00013 20.8 0.1 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Pox_D5 PF03288.11 CEP14325.1 - 3.8e-05 23.8 1.3 0.00018 21.6 0.0 2.7 3 0 0 3 3 3 1 Poxvirus D5 protein-like EMP70 PF02990.11 CEP14327.1 - 1.6e-199 663.7 3.4 1.9e-199 663.4 2.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TCTP PF00838.12 CEP14329.1 - 2.2e-62 209.9 1.9 2.5e-62 209.7 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Histone_HNS PF00816.16 CEP14329.1 - 0.003 18.0 0.1 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 H-NS histone family Cauli_AT PF03233.8 CEP14329.1 - 0.074 12.7 0.6 0.098 12.3 0.4 1.2 1 0 0 1 1 1 0 Aphid transmission protein Sec63 PF02889.11 CEP14331.1 - 4.7e-173 574.6 0.0 7.7e-95 317.7 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CEP14331.1 - 3.1e-55 186.2 1.9 2.1e-28 98.9 0.4 4.7 6 0 0 6 6 6 2 DEAD/DEAH box helicase ResIII PF04851.10 CEP14331.1 - 3.5e-19 69.3 0.1 4.7e-08 33.0 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEP14331.1 - 6.8e-18 64.3 0.0 1.7e-07 30.9 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_19 PF13245.1 CEP14331.1 - 3.2e-07 29.9 0.1 0.014 15.1 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 CEP14331.1 - 7.8e-07 29.2 0.8 0.035 14.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 CEP14331.1 - 8.7e-06 25.9 0.8 0.061 13.5 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CEP14331.1 - 0.00072 19.1 0.1 0.76 9.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CEP14331.1 - 0.0069 15.8 0.0 13 5.0 0.0 3.9 2 1 0 3 3 3 0 AAA-like domain IstB_IS21 PF01695.12 CEP14331.1 - 0.0074 15.7 0.1 7.6 5.9 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein PhoH PF02562.11 CEP14331.1 - 0.0077 15.4 0.0 2.3 7.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_23 PF13476.1 CEP14331.1 - 0.027 14.7 3.9 6.7 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Gp_dh_C PF02800.15 CEP14332.1 - 1.3e-73 245.6 0.0 1.8e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CEP14332.1 - 1.4e-60 203.6 0.0 2.8e-60 202.6 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 CEP14332.1 - 0.022 14.2 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Arf PF00025.16 CEP14333.1 - 2.5e-45 153.8 0.0 3.1e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CEP14333.1 - 9.2e-13 47.8 0.0 1.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP14333.1 - 2.3e-12 47.4 0.0 3.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CEP14333.1 - 4e-10 39.4 0.0 7.7e-09 35.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CEP14333.1 - 5.4e-10 38.5 0.2 5.7e-07 28.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CEP14333.1 - 1.7e-09 37.1 0.0 2.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEP14333.1 - 2.3e-09 36.7 0.0 3.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEP14333.1 - 2e-07 30.9 0.0 3.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.1 CEP14333.1 - 0.0047 17.2 0.0 0.0057 17.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CEP14333.1 - 0.011 14.9 0.1 0.043 13.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2672 PF10878.3 CEP14333.1 - 0.015 15.0 1.4 2.2 8.0 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2672) PduV-EutP PF10662.4 CEP14333.1 - 0.023 14.1 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CEP14333.1 - 0.066 13.3 0.0 0.2 11.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 CEP14333.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CEP14333.1 - 0.077 12.4 0.1 9.6 5.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CEP14333.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CEP14333.1 - 0.087 13.1 0.1 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Phage_integrase PF00589.17 CEP14335.1 - 0.0013 18.4 0.0 0.0045 16.6 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_4 PF13495.1 CEP14335.1 - 0.014 15.7 0.3 0.033 14.5 0.2 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 CEP14335.1 - 0.085 13.0 0.2 0.3 11.2 0.1 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain MFS_1 PF07690.11 CEP14337.1 - 2.5e-48 164.5 45.9 4.3e-48 163.8 30.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP14337.1 - 6.9e-17 61.1 3.2 6.9e-17 61.1 2.2 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 CEP14337.1 - 3.5e-09 35.4 11.2 3.5e-09 35.4 7.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EPL1 PF10513.4 CEP14338.1 - 0.039 14.2 6.0 0.024 14.8 2.9 1.6 2 0 0 2 2 2 0 Enhancer of polycomb-like HECT PF00632.20 CEP14339.1 - 1e-67 228.5 0.1 2.5e-67 227.2 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_C58 PF03543.9 CEP14339.1 - 0.12 11.8 0.2 0.31 10.5 0.2 1.6 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen CDT1 PF08839.6 CEP14340.1 - 0.46 10.3 7.2 0.36 10.7 3.8 1.7 2 1 0 2 2 2 0 DNA replication factor CDT1 like Fer4_7 PF12838.2 CEP14340.1 - 2.1 8.8 6.8 8.2 6.8 2.8 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain YfhO PF09586.5 CEP14340.1 - 2.4 6.0 9.0 2.9 5.7 6.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Sgf11 PF08209.6 CEP14340.1 - 4.5 6.6 6.8 2.9 7.2 0.1 2.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) UPF0515 PF15135.1 CEP14340.1 - 6.4 5.7 14.9 0.3 10.1 3.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Ribosomal_L18p PF00861.17 CEP14341.1 - 1.5e-43 147.8 0.0 2.3e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CEP14341.1 - 2.4e-29 101.7 3.1 2.4e-29 101.7 2.2 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region AKNA PF12443.3 CEP14342.1 - 0.0025 17.8 4.1 0.0025 17.8 2.8 3.6 4 0 0 4 4 4 1 AT-hook-containing transcription factor DUF4298 PF14131.1 CEP14342.1 - 0.15 11.9 4.9 0.095 12.5 1.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) Med9 PF07544.8 CEP14342.1 - 1.3 8.8 15.3 0.082 12.6 3.1 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.7 CEP14342.1 - 1.3 9.3 10.6 7.7 6.8 0.2 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ArdA PF07275.6 CEP14342.1 - 1.4 9.1 12.6 0.38 10.9 0.5 3.1 3 0 0 3 3 3 0 Antirestriction protein (ArdA) Tup_N PF08581.5 CEP14342.1 - 6.7 6.9 22.6 0.083 13.0 5.2 3.0 2 1 1 3 3 3 0 Tup N-terminal 3HCDH_N PF02737.13 CEP14345.1 - 0.09 12.4 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-CCHC PF00098.18 CEP14346.1 - 6.4e-08 32.1 12.5 2.7e-05 23.8 2.1 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP14346.1 - 1.7e-06 27.6 5.3 0.012 15.3 0.0 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CHC2 PF01807.15 CEP14346.1 - 0.049 13.1 0.5 0.19 11.3 0.5 1.8 2 0 0 2 2 2 0 CHC2 zinc finger Cytochrom_C1 PF02167.10 CEP14346.1 - 0.11 12.1 0.4 0.16 11.6 0.3 1.1 1 0 0 1 1 1 0 Cytochrome C1 family RVT_1 PF00078.22 CEP14347.1 - 2.3e-18 66.3 0.2 7.6e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_3 PF14369.1 CEP14348.1 - 1.2e-08 34.8 6.4 0.081 12.9 0.2 4.4 4 0 0 4 4 4 2 zinc-finger zf-CCHC PF00098.18 CEP14348.1 - 2.4e-06 27.2 21.7 0.13 12.2 1.0 4.7 4 0 0 4 4 4 3 Zinc knuckle DUF164 PF02591.10 CEP14348.1 - 0.0004 20.1 9.2 0.24 11.2 0.3 3.9 4 0 0 4 4 4 2 Putative zinc ribbon domain DnaJ_CXXCXGXG PF00684.14 CEP14348.1 - 0.0012 18.8 15.3 0.062 13.3 0.4 3.4 2 1 1 3 3 3 2 DnaJ central domain Zn_Tnp_IS1595 PF12760.2 CEP14348.1 - 0.0034 17.1 19.3 0.2 11.4 0.6 3.7 4 0 0 4 4 4 3 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 CEP14348.1 - 0.0055 16.6 9.8 2.8 7.9 0.2 3.9 3 1 1 4 4 4 1 Zinc ribbon domain UPF0547 PF10571.4 CEP14348.1 - 0.008 15.8 13.6 0.51 10.0 0.3 3.6 4 0 0 4 4 3 2 Uncharacterised protein family UPF0547 DUF2296 PF10058.4 CEP14348.1 - 0.02 14.6 3.8 3.8 7.3 0.2 3.4 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Lar_restr_allev PF14354.1 CEP14348.1 - 0.03 14.6 12.6 0.98 9.7 3.7 3.0 2 1 1 3 3 3 0 Restriction alleviation protein Lar PhnA_Zn_Ribbon PF08274.7 CEP14348.1 - 0.033 13.9 7.5 2.3 8.0 0.1 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 CEP14348.1 - 0.05 12.8 15.4 2.9 7.2 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CEP14348.1 - 0.072 12.6 13.3 3.1 7.4 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Cys_rich_KTR PF14205.1 CEP14348.1 - 0.16 11.4 4.8 19 4.7 0.1 3.4 3 0 0 3 3 3 0 Cysteine-rich KTR FYDLN_acid PF09538.5 CEP14348.1 - 0.18 12.3 1.8 3.9 8.0 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) Terminase_GpA PF05876.7 CEP14348.1 - 0.27 9.5 2.3 0.33 9.2 1.6 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-FCS PF06467.9 CEP14348.1 - 0.4 10.3 4.7 26 4.5 0.1 3.3 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 CEP14348.1 - 0.46 10.6 10.5 6.8 6.8 0.2 3.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 CEP14348.1 - 0.55 10.0 12.6 2.1e+02 1.8 8.7 2.9 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L32p PF01783.18 CEP14348.1 - 0.58 10.3 9.0 16 5.7 0.2 3.6 1 1 2 3 3 3 0 Ribosomal L32p protein family DNA_RNApol_7kD PF03604.8 CEP14348.1 - 0.66 9.4 6.7 19 4.8 0.2 3.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-LITAF-like PF10601.4 CEP14348.1 - 1.3 8.9 9.7 8.7 6.2 0.1 3.4 4 0 0 4 4 3 0 LITAF-like zinc ribbon domain DUF1272 PF06906.6 CEP14348.1 - 1.6 8.6 8.1 6.4 6.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) zf-C4_ClpX PF06689.8 CEP14348.1 - 1.6 8.2 5.7 41 3.8 0.0 3.3 3 0 0 3 3 3 0 ClpX C4-type zinc finger zf-C4_Topoisom PF01396.14 CEP14348.1 - 1.6 8.2 12.4 7.7 6.1 0.1 4.1 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger Cys_rich_CPXG PF14255.1 CEP14348.1 - 2.1 8.2 11.1 24 4.8 0.4 3.7 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-FPG_IleRS PF06827.9 CEP14348.1 - 2.2 8.0 7.5 13 5.5 0.1 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS HypA PF01155.14 CEP14348.1 - 2.7 7.7 8.4 46 3.7 0.4 2.7 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 CEP14348.1 - 3.6 7.3 16.5 5.7 6.7 1.2 3.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-TFIIB PF13453.1 CEP14348.1 - 7.3 5.8 10.7 6.7 5.9 0.2 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger Ogr_Delta PF04606.7 CEP14348.1 - 7.5 6.2 22.9 2 8.1 0.4 4.3 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_4 PF13894.1 CEP14348.1 - 9.7 6.7 9.9 58 4.3 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger DDE_3 PF13358.1 CEP14349.1 - 4.8e-07 29.6 0.0 8.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP14349.1 - 0.0042 17.8 0.0 0.052 14.3 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP14349.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Hamartin PF04388.7 CEP14350.1 - 9.2e-29 100.6 19.2 3.3e-28 98.8 13.3 1.9 1 1 0 1 1 1 1 Hamartin protein V-SNARE_C PF12352.3 CEP14350.1 - 0.045 13.8 3.1 0.049 13.7 0.2 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus WD40_alt PF14077.1 CEP14350.1 - 0.066 12.8 0.7 0.2 11.3 0.5 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif Pox_A_type_inc PF04508.7 CEP14350.1 - 0.13 12.0 1.2 15 5.6 0.2 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF3584 PF12128.3 CEP14350.1 - 3.2 4.9 45.3 0.019 12.3 24.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DDE_3 PF13358.1 CEP14351.1 - 7.3e-17 61.4 0.0 1.5e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP14351.1 - 7.5e-05 22.8 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP14351.1 - 0.00037 20.4 0.4 0.0018 18.2 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP14351.1 - 0.0015 19.2 0.0 0.0042 17.8 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 CEP14351.1 - 0.029 14.3 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.1 CEP14351.1 - 0.072 12.7 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.1 CEP14352.1 - 1.3e-26 93.1 0.0 2.4e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP14352.1 - 2.3e-05 24.5 0.4 5.3e-05 23.3 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_psq PF05225.11 CEP14352.1 - 5.3e-05 22.6 0.0 0.00041 19.8 0.0 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP14352.1 - 9.1e-05 22.3 1.2 0.00026 20.9 0.8 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP14352.1 - 0.00024 21.8 1.4 0.0032 18.2 0.0 3.1 3 1 0 3 3 3 1 Homeodomain-like domain CENP-B_N PF04218.8 CEP14352.1 - 0.0014 18.0 0.0 0.0033 16.7 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 CEP14352.1 - 0.0025 17.3 0.2 0.0081 15.7 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_37 PF13744.1 CEP14352.1 - 0.014 15.1 0.2 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.5 CEP14352.1 - 0.017 14.8 0.2 0.075 12.7 0.0 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_3 PF01381.17 CEP14352.1 - 0.019 14.7 0.1 0.053 13.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.11 CEP14352.1 - 0.022 14.0 0.9 0.082 12.2 0.2 2.2 3 0 0 3 3 3 0 Sigma-70, region 4 DDE_1 PF03184.14 CEP14352.1 - 0.026 13.6 0.1 0.072 12.2 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease HTH_17 PF12728.2 CEP14352.1 - 0.075 13.2 0.2 0.22 11.8 0.1 1.8 2 0 0 2 2 1 0 Helix-turn-helix domain zf-C2H2_jaz PF12171.3 CEP14353.1 - 0.0031 17.6 0.5 0.0095 16.0 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CEP14353.1 - 0.0093 16.2 2.7 0.096 13.0 0.2 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.2 CEP14353.1 - 0.058 13.6 0.1 0.28 11.4 0.1 2.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CEP14353.1 - 0.27 11.6 2.3 0.52 10.7 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PIF1 PF05970.9 CEP14354.1 - 8.2e-33 113.8 0.1 1.4e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP14354.1 - 4.9e-08 32.7 0.0 1.8e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP14354.1 - 0.0007 19.7 0.0 0.0038 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CEP14354.1 - 0.0017 17.8 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 CEP14354.1 - 0.0036 17.4 0.0 0.04 14.0 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_19 PF13245.1 CEP14354.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 CEP14354.1 - 0.055 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CEP14354.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 CEP14354.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CEP14354.1 - 0.092 12.3 0.1 0.9 9.1 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA PF00004.24 CEP14354.1 - 0.12 12.5 0.0 0.44 10.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RhoGAP PF00620.22 CEP14356.1 - 1.3e-14 54.0 0.7 1.3e-14 54.0 0.5 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CEP14356.1 - 0.022 14.9 0.0 0.086 13.0 0.0 2.1 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 CEP14356.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Rotamase PF00639.16 CEP14357.1 - 9.7e-26 90.3 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CEP14357.1 - 1.6e-18 67.0 0.0 1.9e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CEP14357.1 - 9.5e-08 31.7 2.9 2e-07 30.7 2.0 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 CEP14357.1 - 3e-05 24.6 0.0 4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Duffy_binding PF05424.6 CEP14357.1 - 0.05 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Duffy binding domain BK_channel_a PF03493.13 CEP14358.1 - 1.9e-22 79.1 0.1 1e-20 73.5 0.0 3.0 2 1 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 CEP14358.1 - 2.8e-14 52.5 2.4 2.8e-14 52.5 1.6 2.1 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.13 CEP14358.1 - 3.9e-05 23.6 0.0 0.096 12.6 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.26 CEP14358.1 - 0.047 12.9 13.0 0.095 11.9 9.0 1.4 1 0 0 1 1 1 0 Ion transport protein DDE_3 PF13358.1 CEP14359.1 - 2.2e-13 50.1 0.0 2.5e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.27 CEP14360.1 - 1.1e-19 69.5 17.7 1.8e-07 30.7 0.1 6.5 5 1 1 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 CEP14361.1 - 0.00019 21.1 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP14361.1 - 0.0069 16.0 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain DDE_3 PF13358.1 CEP14362.1 - 3.6e-30 104.6 0.2 1.3e-29 102.8 0.0 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP14362.1 - 3.6e-06 27.1 0.0 6.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP14362.1 - 0.00018 21.0 0.0 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 CEP14362.1 - 0.0003 21.5 0.0 0.00095 19.9 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP14362.1 - 0.00041 20.2 0.2 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_1 PF03184.14 CEP14362.1 - 0.0045 16.1 0.0 0.011 14.8 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Terminase_5 PF06056.7 CEP14362.1 - 0.0099 15.4 0.2 0.025 14.1 0.0 1.7 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) rve PF00665.21 CEP14362.1 - 0.017 15.1 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_1 PF01527.15 CEP14362.1 - 0.029 14.3 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Transposase TauD PF02668.11 CEP14363.1 - 6.3e-53 180.0 0.9 7.6e-53 179.8 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1958 PF09211.5 CEP14364.1 - 0.046 13.7 0.1 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) LRR_8 PF13855.1 CEP14364.1 - 0.1 12.3 1.1 15 5.4 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CEP14364.1 - 0.28 10.8 3.5 2.4 7.8 0.2 3.7 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) CotH PF08757.6 CEP14365.1 - 1.2e-42 146.3 2.3 1.5e-42 146.0 1.6 1.1 1 0 0 1 1 1 1 CotH protein DUF4211 PF13926.1 CEP14365.1 - 0.14 11.5 0.5 6.7 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) SKG6 PF08693.5 CEP14366.1 - 0.0093 15.2 0.8 0.019 14.2 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 CEP14366.1 - 0.018 14.6 1.2 0.024 14.1 0.8 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 7TM_GPCR_Srv PF10323.4 CEP14366.1 - 0.077 12.1 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv EphA2_TM PF14575.1 CEP14366.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 CEP14366.1 - 0.63 10.1 0.0 0.63 10.1 0.0 2.9 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator TRP PF06011.7 CEP14366.1 - 1.1 7.7 5.9 2.6 6.5 4.1 1.7 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel PsbJ PF01788.12 CEP14366.1 - 3.6 7.2 4.9 6.3 6.4 3.4 1.3 1 0 0 1 1 1 0 PsbJ Peptidase_C12 PF01088.16 CEP14367.1 - 1.6e-63 213.7 0.1 3.2e-63 212.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UBX PF00789.15 CEP14367.1 - 4e-08 33.2 0.1 2.8e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 UBX domain DUF3759 PF12585.3 CEP14368.1 - 1.2e-34 118.0 6.4 1.4e-34 117.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) MMtag PF10159.4 CEP14368.1 - 0.0074 16.2 0.8 0.016 15.2 0.2 1.8 1 1 0 1 1 1 1 Kinase phosphorylation protein DPRP PF04244.8 CEP14368.1 - 0.011 15.2 0.6 0.011 15.2 0.4 1.1 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein DUF3419 PF11899.3 CEP14368.1 - 0.012 14.3 0.1 0.015 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Peptidase_A8 PF01252.13 CEP14368.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Signal peptidase (SPase) II Peptidase_M24 PF00557.19 CEP14369.1 - 5.1e-46 156.8 0.1 6.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Prp18 PF02840.10 CEP14369.1 - 0.012 15.4 0.1 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain SRA1 PF07304.6 CEP14369.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF1363 PF07101.6 CEP14370.1 - 0.002 18.2 0.4 0.011 15.7 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1363) GFA PF04828.9 CEP14370.1 - 0.022 14.7 0.4 0.036 14.0 0.3 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme E6 PF00518.12 CEP14370.1 - 0.076 13.3 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Early Protein (E6) Helitron_like_N PF14214.1 CEP14371.1 - 1.2e-35 122.9 0.1 2.1e-28 99.2 0.0 2.5 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus DUSP PF06337.7 CEP14375.1 - 1.3e-09 38.3 0.1 4.5e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 DUSP domain zf-UBP PF02148.14 CEP14375.1 - 2.8e-07 30.5 5.4 5.2e-07 29.6 3.0 1.9 1 1 1 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein F-box PF00646.28 CEP14375.1 - 0.0031 17.1 0.1 0.01 15.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEP14375.1 - 0.0032 17.1 0.0 0.0081 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like RNA_pol_N PF01194.12 CEP14375.1 - 0.18 11.8 3.7 9.4 6.3 0.0 3.0 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit Maf1 PF09174.5 CEP14376.1 - 1.7e-22 80.1 0.0 4e-22 78.9 0.0 1.6 1 1 0 1 1 1 1 Maf1 regulator zf-C2H2 PF00096.21 CEP14377.1 - 1.1e-08 34.9 7.0 3.5e-05 23.8 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP14377.1 - 3.4e-07 30.2 1.3 3.4e-07 30.2 0.9 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP14377.1 - 1.6e-05 24.8 8.7 0.0016 18.6 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP14377.1 - 0.00051 19.8 0.7 0.0048 16.7 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Macoilin PF09726.4 CEP14377.1 - 3.9 5.6 8.6 4.5 5.4 5.9 1.0 1 0 0 1 1 1 0 Transmembrane protein HIG_1_N PF04588.8 CEP14378.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hypoxia induced protein conserved region TIM PF00121.13 CEP14379.1 - 1.2e-91 306.1 0.0 1.3e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Thioredoxin_7 PF13899.1 CEP14380.1 - 1.2e-16 60.4 0.0 2.4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 CEP14380.1 - 7.6e-13 48.3 0.0 2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CEP14380.1 - 1.7e-09 37.0 0.4 4.4e-09 35.7 0.3 1.8 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.1 CEP14380.1 - 0.0075 16.4 0.1 0.054 13.7 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain UIM PF02809.15 CEP14380.1 - 0.026 14.0 0.1 0.088 12.4 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.10 CEP14380.1 - 0.058 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 HATPase_c_5 PF14501.1 CEP14381.1 - 0.022 14.4 0.3 0.044 13.4 0.2 1.5 1 0 0 1 1 1 0 GHKL domain DUF1642 PF07852.6 CEP14381.1 - 0.036 14.4 0.4 0.062 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Mer2 PF09074.5 CEP14381.1 - 0.1 12.5 3.3 0.38 10.6 2.3 1.9 1 1 0 1 1 1 0 Mer2 CLPTM1 PF05602.7 CEP14382.1 - 0.00096 17.9 0.4 0.0015 17.3 0.3 1.3 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF962 PF06127.6 CEP14383.1 - 0.2 11.6 0.5 6.4 6.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF962) RVT_1 PF00078.22 CEP14385.1 - 1.5e-12 47.3 0.9 2.7e-12 46.4 0.6 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Oxysterol_BP PF01237.13 CEP14386.1 - 1.2e-77 260.8 3.0 1.4e-77 260.6 2.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Hexokinase_2 PF03727.11 CEP14387.1 - 5.9e-70 235.2 0.0 9.9e-70 234.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEP14387.1 - 8.2e-56 188.5 0.0 1.2e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1160 PF06648.6 CEP14387.1 - 0.032 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Vps5 PF09325.5 CEP14388.1 - 1.6e-12 47.1 12.5 1.6e-12 47.1 8.7 2.6 2 1 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 CEP14388.1 - 1.8e-09 37.3 0.2 1.8e-09 37.3 0.1 2.3 2 1 0 2 2 2 1 PX domain Serpulina_VSP PF05540.6 CEP14388.1 - 0.053 12.2 0.4 0.09 11.5 0.3 1.3 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein T2SM PF04612.7 CEP14388.1 - 6 6.6 6.7 5 6.8 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M RabGAP-TBC PF00566.13 CEP14389.1 - 1.4e-45 155.3 3.8 3.9e-45 153.9 2.7 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF2051 PF09738.4 CEP14389.1 - 0.093 11.9 3.1 0.47 9.6 2.3 1.9 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Chitin_synth_2 PF03142.10 CEP14390.1 - 3.5e-234 778.0 2.9 5.1e-234 777.5 2.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEP14390.1 - 8.1e-125 417.4 6.3 2.6e-123 412.4 4.4 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 CEP14390.1 - 3e-17 62.9 4.5 3e-17 62.9 3.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP14390.1 - 6.3e-17 62.1 0.0 2.3e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CEP14390.1 - 7.3e-17 60.9 0.9 8.7e-10 38.2 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 CEP14390.1 - 5.3e-16 58.1 1.1 5.5e-15 54.8 1.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 CEP14390.1 - 6.3e-05 22.3 0.1 0.0012 18.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CEP14390.1 - 0.0035 17.0 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2392 PF10288.4 CEP14391.1 - 4.5e-25 88.0 0.7 1e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) c-SKI_SMAD_bind PF08782.5 CEP14391.1 - 0.023 14.7 0.1 0.58 10.3 0.0 2.4 2 0 0 2 2 2 0 c-SKI Smad4 binding domain ATP_bind_3 PF01171.15 CEP14391.1 - 0.041 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 PP-loop family SLAC1 PF03595.12 CEP14393.1 - 5.3e-52 176.4 24.1 6e-52 176.3 16.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Ras PF00071.17 CEP14394.1 - 1.4e-46 157.7 0.6 1.9e-46 157.4 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP14394.1 - 2.3e-09 37.7 0.0 4.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP14394.1 - 8.4e-09 34.9 0.2 1.1e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP14394.1 - 0.00041 19.8 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP14394.1 - 0.0062 15.7 0.2 0.0089 15.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PP1c_bdg PF10488.4 CEP14394.1 - 0.018 14.2 0.9 0.023 13.9 0.6 1.1 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Glyco_hydro_15 PF00723.16 CEP14395.1 - 4.5e-65 219.9 0.1 6e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 RNase_T PF00929.19 CEP14396.1 - 9.4e-25 87.7 0.0 1.7e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CEP14396.1 - 0.0017 17.8 0.0 0.018 14.5 0.0 2.5 1 1 1 2 2 2 1 3'-5' exonuclease FAM60A PF15396.1 CEP14396.1 - 1.6 8.3 11.8 0.54 9.9 0.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A ING PF12998.2 CEP14397.1 - 5e-18 65.2 8.8 7.8e-18 64.6 6.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CEP14397.1 - 2.1e-09 36.9 8.7 3.8e-09 36.0 6.0 1.4 1 0 0 1 1 1 1 PHD-finger CENP-Q PF13094.1 CEP14397.1 - 0.0066 16.4 3.5 0.0066 16.4 2.4 1.5 2 0 0 2 2 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 CEP14397.1 - 0.0091 14.9 2.5 0.013 14.5 1.8 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-HC5HC2H PF13771.1 CEP14397.1 - 0.017 15.2 1.1 0.045 13.9 0.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Spc7 PF08317.6 CEP14397.1 - 0.019 13.6 2.5 0.026 13.1 1.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF288 PF03385.12 CEP14397.1 - 0.039 12.4 0.8 0.064 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF288 PHD_2 PF13831.1 CEP14397.1 - 0.075 12.3 3.3 0.16 11.3 2.3 1.5 1 0 0 1 1 1 0 PHD-finger AAA_27 PF13514.1 CEP14397.1 - 0.1 10.2 2.6 0.13 9.9 1.8 1.0 1 0 0 1 1 1 0 AAA domain DASH_Dam1 PF08653.5 CEP14397.1 - 0.12 12.1 1.3 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 Fib_alpha PF08702.5 CEP14397.1 - 0.14 12.3 5.9 0.26 11.3 4.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 CEP14397.1 - 0.21 9.9 1.9 0.29 9.5 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Amidase PF01425.16 CEP14398.1 - 4.5e-91 305.9 0.0 5.6e-91 305.5 0.0 1.0 1 0 0 1 1 1 1 Amidase Utp13 PF08625.6 CEP14399.1 - 0.064 12.9 0.2 0.078 12.6 0.1 1.1 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Thioredoxin PF00085.15 CEP14400.1 - 1.1e-28 98.8 0.2 1.4e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CEP14400.1 - 5.7e-07 29.7 0.0 2.5e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEP14400.1 - 1.3e-06 28.4 0.1 1.2e-05 25.3 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CEP14400.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CEP14400.1 - 5.5e-05 22.7 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CEP14400.1 - 0.00027 20.6 0.1 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 CEP14400.1 - 0.00066 19.3 0.1 0.001 18.7 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.9 CEP14400.1 - 0.0049 17.0 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Redoxin PF08534.5 CEP14400.1 - 0.021 14.3 1.3 0.77 9.2 0.4 2.1 1 1 1 2 2 2 0 Redoxin Phosducin PF02114.11 CEP14400.1 - 0.044 12.5 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosducin Nic96 PF04097.9 CEP14401.1 - 6.5e-104 348.2 13.9 9.4e-104 347.7 9.6 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Kelch_4 PF13418.1 CEP14402.1 - 5.2e-23 80.5 20.0 6.3e-06 25.8 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP14402.1 - 1.5e-17 63.1 22.9 4.3e-05 23.5 0.2 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP14402.1 - 3.4e-17 61.7 19.2 0.0022 18.0 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 CEP14402.1 - 1.1e-16 60.3 3.8 0.0012 18.7 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CEP14402.1 - 7e-09 35.0 11.7 0.00011 21.7 0.1 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CEP14402.1 - 2.7e-07 30.0 5.6 5.6 6.8 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Agro_virD5 PF04730.7 CEP14403.1 - 0.0065 14.6 0.0 0.008 14.3 0.0 1.1 1 0 0 1 1 1 1 Agrobacterium VirD5 protein MULE PF10551.4 CEP14403.1 - 0.026 14.6 0.0 0.059 13.5 0.0 1.6 2 0 0 2 2 2 0 MULE transposase domain DUF4506 PF14958.1 CEP14403.1 - 0.047 13.2 0.7 0.07 12.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) PUF PF00806.14 CEP14404.1 - 3e-66 215.3 19.4 1.4e-08 33.7 0.0 9.1 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CUE PF02845.11 CEP14405.1 - 7.3e-11 41.3 0.0 1.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF2252 PF10009.4 CEP14405.1 - 0.041 12.7 2.8 0.058 12.3 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Ndc1_Nup PF09531.5 CEP14405.1 - 2.9 6.2 7.5 3.5 5.9 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DEAD PF00270.24 CEP14406.1 - 1.9e-40 138.1 0.7 6.6e-40 136.3 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP14406.1 - 1.9e-18 66.1 0.1 4.8e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CEP14406.1 - 6.9e-05 21.7 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CEP14406.1 - 7.8e-05 22.5 0.2 0.00024 20.9 0.1 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CEP14406.1 - 0.0018 17.9 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 CEP14406.1 - 0.0064 15.7 0.1 0.019 14.1 0.0 1.8 1 0 0 1 1 1 1 PhoH-like protein SecA_DEAD PF07517.9 CEP14406.1 - 0.0067 15.7 0.1 0.023 14.0 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 CEP14406.1 - 0.0096 16.0 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CEP14406.1 - 0.043 12.8 0.0 0.11 11.3 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RRM_1 PF00076.17 CEP14407.1 - 1.1e-33 114.6 0.0 4.1e-14 51.9 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP14407.1 - 1.3e-21 76.2 0.0 1.4e-07 31.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP14407.1 - 9.9e-19 66.9 0.0 1.2e-05 25.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 CEP14407.1 - 0.06 13.0 39.7 0.13 11.9 27.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1866 PF08952.6 CEP14407.1 - 0.074 12.5 0.1 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF4290 PF14123.1 CEP14407.1 - 0.08 12.1 0.1 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) Nup35_RRM PF05172.8 CEP14407.1 - 0.16 11.7 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 CEP14407.1 - 1.9 6.8 10.4 2.6 6.4 7.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LRR_6 PF13516.1 CEP14408.1 - 1.2 9.3 7.9 33 4.9 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat AOX PF01786.12 CEP14409.1 - 8.4e-75 250.7 0.0 1.1e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase ABC_sub_bind PF04392.7 CEP14410.1 - 0.0037 16.2 0.1 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 ABC transporter substrate binding protein SH3_1 PF00018.23 CEP14411.1 - 8.2e-14 50.7 0.1 1.6e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP14411.1 - 8.2e-10 38.1 0.0 1.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP14411.1 - 2.2e-08 33.4 0.0 4.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CEP14411.1 - 0.00091 19.3 0.1 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain ABC2_membrane_2 PF12679.2 CEP14411.1 - 0.2 10.4 6.3 0.25 10.1 4.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2040 PF09745.4 CEP14412.1 - 3.5e-35 120.6 21.6 3.5e-35 120.6 15.0 4.1 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) ER_lumen_recept PF00810.13 CEP14413.1 - 4e-47 160.4 12.0 6.2e-47 159.7 8.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor cNMP_binding PF00027.24 CEP14413.1 - 5.1e-40 135.1 0.0 6.2e-19 67.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CEP14413.1 - 6.2e-08 31.9 4.3 1.2e-07 31.0 3.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.1 CEP14414.1 - 1.1e-17 63.8 8.5 1.9e-14 53.5 2.4 3.2 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CEP14414.1 - 3.4e-17 60.3 8.1 3.3e-06 26.0 0.7 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CEP14414.1 - 5.9e-14 50.6 5.8 0.00035 20.2 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 CEP14414.1 - 4.5e-11 41.5 5.3 1.4e-05 24.2 0.3 3.4 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CEP14414.1 - 2.4e-10 39.8 10.5 0.00011 21.7 3.5 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CEP14414.1 - 4.8e-05 23.0 5.3 0.15 11.7 0.2 3.2 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CEP14414.1 - 9e-05 22.4 3.4 0.002 18.1 0.3 3.5 2 2 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Haemagg_act PF05860.8 CEP14414.1 - 0.00062 19.5 0.9 2.5 7.8 0.0 3.2 1 1 1 2 2 2 2 haemagglutination activity domain Fumble PF03630.9 CEP14414.1 - 0.032 13.1 2.8 0.049 12.4 0.4 1.9 1 1 0 2 2 2 0 Fumble zf-met PF12874.2 CEP14415.1 - 2.3e-12 46.6 76.5 0.019 15.1 0.5 11.4 11 0 0 11 11 11 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP14415.1 - 4.1e-05 23.5 91.1 0.0018 18.3 0.6 10.8 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-Dof PF02701.10 CEP14415.1 - 0.15 12.0 0.2 0.15 12.0 0.1 6.4 7 0 0 7 7 7 0 Dof domain, zinc finger HSF_DNA-bind PF00447.12 CEP14416.1 - 7.9e-31 106.3 0.4 7.9e-31 106.3 0.3 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding DUF3135 PF11333.3 CEP14416.1 - 0.0096 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) F5_F8_type_C PF00754.20 CEP14417.1 - 0.04 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain Med12-LCEWAV PF12145.3 CEP14418.1 - 0.018 13.5 0.0 0.028 12.9 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Rotamase PF00639.16 CEP14419.1 - 9.4e-17 61.5 0.1 2.9e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CEP14419.1 - 1.6e-15 57.3 0.1 3.8e-15 56.1 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CEP14419.1 - 0.0019 18.8 0.3 0.0079 16.8 0.2 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain PV-1 PF06637.6 CEP14420.1 - 0.016 13.7 0.2 0.021 13.3 0.1 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) SFTA2 PF15210.1 CEP14420.1 - 0.12 12.0 0.5 0.31 10.6 0.3 1.7 1 0 0 1 1 1 0 Surfactant-associated protein 2 SprA-related PF12118.3 CEP14420.1 - 1.7 7.9 6.2 2.1 7.6 4.3 1.1 1 0 0 1 1 1 0 SprA-related family Ribosomal_L28e PF01778.12 CEP14421.1 - 0.14 12.5 0.5 0.14 12.5 0.3 1.9 2 0 0 2 2 2 0 Ribosomal L28e protein family MBD_C PF14048.1 CEP14421.1 - 0.33 11.5 3.6 0.64 10.6 0.9 2.2 2 1 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 PRCC PF10253.4 CEP14421.1 - 3.2 8.4 9.3 4.6 7.8 6.4 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SUR7 PF06687.7 CEP14422.1 - 1.3e-19 70.6 18.6 2e-19 70.0 12.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family Cyclin PF08613.6 CEP14423.1 - 2.6e-37 128.5 1.6 3.4e-37 128.1 1.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP14423.1 - 5.7e-06 25.9 0.1 7.2e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain MT-A70 PF05063.9 CEP14424.1 - 4.4e-39 133.8 0.0 6e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 CENP-B_N PF04218.8 CEP14424.1 - 0.029 13.8 0.2 0.053 12.9 0.2 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Methyltransf_26 PF13659.1 CEP14424.1 - 0.052 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF904 PF06005.7 CEP14424.1 - 0.058 13.6 0.5 0.13 12.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Cons_hypoth95 PF03602.10 CEP14424.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0197 PF05251.7 CEP14427.1 - 0.00014 22.1 1.5 0.00023 21.3 1.1 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) TOM13 PF08219.6 CEP14428.1 - 7.8e-19 67.2 0.2 7.8e-19 67.2 0.1 1.5 2 0 0 2 2 2 1 Outer membrane protein TOM13 OrfB_Zn_ribbon PF07282.6 CEP14429.1 - 3.1e-10 39.5 0.1 9e-10 38.0 0.1 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PH_6 PF15406.1 CEP14429.1 - 0.034 14.2 0.5 10 6.2 0.0 3.0 2 1 0 3 3 3 0 Pleckstrin homology domain Tropomyosin_1 PF12718.2 CEP14430.1 - 3.1e-16 59.5 24.2 6.1e-16 58.5 16.8 1.5 1 1 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CEP14430.1 - 3.3e-07 29.6 22.5 3.2e-06 26.4 15.0 1.9 1 1 0 1 1 1 1 Tropomyosin Laminin_I PF06008.9 CEP14430.1 - 2e-05 24.0 12.1 2.8e-05 23.5 8.4 1.3 1 1 0 1 1 1 1 Laminin Domain I DUF4201 PF13870.1 CEP14430.1 - 0.00015 21.2 7.2 0.00015 21.2 5.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Nup54 PF13874.1 CEP14430.1 - 0.00018 21.2 6.7 0.00018 21.2 4.6 2.1 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 IncA PF04156.9 CEP14430.1 - 0.00031 20.4 20.2 0.001 18.7 14.0 1.7 1 1 0 1 1 1 1 IncA protein Fib_alpha PF08702.5 CEP14430.1 - 0.00041 20.5 12.7 0.054 13.6 1.7 2.0 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 CEP14430.1 - 0.00043 20.0 13.6 0.042 13.6 1.0 2.1 1 1 1 2 2 2 2 Laminin Domain II WXG100 PF06013.7 CEP14430.1 - 0.00055 19.8 7.6 0.077 13.0 2.2 2.8 2 1 0 2 2 2 1 Proteins of 100 residues with WXG NPV_P10 PF05531.7 CEP14430.1 - 0.00079 19.6 7.7 0.17 12.1 0.6 2.7 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Vps5 PF09325.5 CEP14430.1 - 0.0011 18.3 17.0 0.16 11.1 2.2 2.9 1 1 2 3 3 3 1 Vps5 C terminal like Prefoldin_2 PF01920.15 CEP14430.1 - 0.0013 18.4 25.3 0.39 10.4 4.0 3.2 1 1 2 3 3 3 2 Prefoldin subunit Spc7 PF08317.6 CEP14430.1 - 0.0025 16.5 13.5 0.0025 16.5 9.4 1.9 1 1 1 2 2 2 2 Spc7 kinetochore protein AAA_13 PF13166.1 CEP14430.1 - 0.0031 16.0 17.2 0.0044 15.5 11.9 1.3 1 0 0 1 1 1 1 AAA domain MscS_porin PF12795.2 CEP14430.1 - 0.0032 16.8 16.0 0.12 11.7 11.6 2.0 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain GAS PF13851.1 CEP14430.1 - 0.0033 16.6 23.6 0.016 14.3 16.4 1.8 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding EzrA PF06160.7 CEP14430.1 - 0.0038 15.4 17.6 0.0057 14.9 12.2 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF2730 PF10805.3 CEP14430.1 - 0.0039 16.9 10.1 0.011 15.4 2.4 2.4 1 1 2 3 3 3 2 Protein of unknown function (DUF2730) TPR_MLP1_2 PF07926.7 CEP14430.1 - 0.0046 16.7 20.9 0.011 15.5 14.5 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 CEP14430.1 - 0.0052 16.5 28.0 0.24 11.2 4.1 2.7 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 CEP14430.1 - 0.0058 16.2 20.5 0.023 14.2 8.0 2.1 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Myosin_tail_1 PF01576.14 CEP14430.1 - 0.008 13.9 23.7 0.011 13.5 16.5 1.2 1 0 0 1 1 1 1 Myosin tail DUF1664 PF07889.7 CEP14430.1 - 0.0087 15.8 11.4 0.17 11.6 1.6 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.5 CEP14430.1 - 0.0097 15.9 10.1 0.0097 15.9 7.0 2.1 1 1 1 2 2 2 1 Cortexillin I, coiled coil ATG16 PF08614.6 CEP14430.1 - 0.011 15.5 19.8 0.55 10.0 4.0 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.1 CEP14430.1 - 0.013 14.9 21.5 0.02 14.3 14.9 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GrpE PF01025.14 CEP14430.1 - 0.014 14.9 3.2 0.014 14.9 2.2 2.8 1 1 2 3 3 3 0 GrpE WEMBL PF05701.6 CEP14430.1 - 0.014 13.8 21.3 3.4 6.0 2.4 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ERM PF00769.14 CEP14430.1 - 0.015 14.8 23.2 0.018 14.6 16.0 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.4 CEP14430.1 - 0.017 15.2 15.5 0.2 11.8 4.1 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF869 PF05911.6 CEP14430.1 - 0.017 13.3 19.2 0.019 13.2 13.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) MAD PF05557.8 CEP14430.1 - 0.025 12.6 20.6 0.16 10.0 14.3 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein Prok-TraM PF09228.5 CEP14430.1 - 0.026 14.6 8.2 0.38 10.9 1.4 2.1 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM HalX PF08663.5 CEP14430.1 - 0.03 14.3 17.0 0.2 11.6 1.3 3.4 2 1 1 3 3 3 0 HalX domain FliD_C PF07195.7 CEP14430.1 - 0.03 13.6 12.1 0.67 9.2 8.4 2.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Reo_sigmaC PF04582.7 CEP14430.1 - 0.03 13.4 1.1 0.059 12.5 0.8 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 CEP14430.1 - 0.037 13.4 24.1 0.69 9.4 1.9 3.1 1 1 2 3 3 3 0 Septum formation initiator HCMV_UL139 PF12507.3 CEP14430.1 - 0.042 14.0 1.9 0.13 12.4 0.1 2.1 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Atg14 PF10186.4 CEP14430.1 - 0.043 12.7 15.3 0.044 12.7 4.5 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 CEP14430.1 - 0.044 13.6 7.2 0.085 12.6 2.4 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 CEP14430.1 - 0.045 13.6 18.0 0.071 13.0 11.6 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 CEP14430.1 - 0.05 13.4 10.0 0.23 11.3 1.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 CEP14430.1 - 0.05 13.5 23.9 0.032 14.1 11.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Kinetocho_Slk19 PF12709.2 CEP14430.1 - 0.051 13.6 18.0 0.48 10.5 1.6 3.0 1 1 1 2 2 2 0 Central kinetochore-associated DUF2968 PF11180.3 CEP14430.1 - 0.054 12.8 11.8 0.31 10.4 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) CCDC155 PF14662.1 CEP14430.1 - 0.056 13.0 20.6 0.077 12.5 14.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF2959 PF11172.3 CEP14430.1 - 0.056 13.1 10.5 0.14 11.9 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Sec34 PF04136.10 CEP14430.1 - 0.062 12.9 8.8 0.14 11.9 3.0 2.0 1 1 1 2 2 2 0 Sec34-like family FliJ PF02050.11 CEP14430.1 - 0.063 13.3 17.8 0.28 11.2 6.7 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein DUF3584 PF12128.3 CEP14430.1 - 0.066 10.5 16.9 0.076 10.3 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.4 CEP14430.1 - 0.069 11.6 15.1 0.079 11.4 10.5 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1202 PF06717.6 CEP14430.1 - 0.071 12.3 7.6 0.5 9.5 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1202) HCR PF07111.7 CEP14430.1 - 0.074 11.0 12.7 0.081 10.9 8.8 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) PilJ PF13675.1 CEP14430.1 - 0.08 13.2 4.8 3 8.1 1.5 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Uds1 PF15456.1 CEP14430.1 - 0.095 12.6 15.8 0.073 13.0 5.7 2.3 1 1 1 2 2 2 0 Up-regulated During Septation RmuC PF02646.11 CEP14430.1 - 0.097 11.5 11.7 0.6 8.8 1.0 2.2 1 1 1 2 2 2 0 RmuC family TMF_TATA_bd PF12325.3 CEP14430.1 - 0.099 12.3 18.7 0.023 14.4 8.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.4 CEP14430.1 - 0.1 12.6 15.6 0.14 12.2 5.1 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Snapin_Pallidin PF14712.1 CEP14430.1 - 0.1 12.8 12.7 0.91 9.8 3.5 2.9 1 1 1 3 3 3 0 Snapin/Pallidin Filament PF00038.16 CEP14430.1 - 0.11 11.9 18.2 0.6 9.5 12.6 1.9 1 1 0 1 1 1 0 Intermediate filament protein Mnd1 PF03962.10 CEP14430.1 - 0.12 12.0 19.2 0.46 10.1 13.3 1.8 1 1 0 1 1 1 0 Mnd1 family FlxA PF14282.1 CEP14430.1 - 0.13 12.2 14.6 0.11 12.4 4.2 2.3 1 1 1 2 2 2 0 FlxA-like protein Fmp27_WPPW PF10359.4 CEP14430.1 - 0.13 10.6 15.0 0.075 11.4 4.6 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF745 PF05335.8 CEP14430.1 - 0.15 11.5 13.5 0.2 11.1 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Troponin PF00992.15 CEP14430.1 - 0.15 12.0 18.6 0.54 10.3 12.7 1.9 1 1 0 1 1 1 0 Troponin Cast PF10174.4 CEP14430.1 - 0.16 10.0 21.0 0.29 9.1 14.5 1.5 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF585 PF04522.7 CEP14430.1 - 0.16 11.3 3.1 0.082 12.2 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF585) APG6 PF04111.7 CEP14430.1 - 0.17 10.9 21.5 0.21 10.5 14.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 CEP14430.1 - 0.18 11.6 23.8 0.17 11.7 10.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.7 CEP14430.1 - 0.18 12.2 15.5 0.39 11.1 2.0 3.0 1 1 2 3 3 3 0 SlyX IFT57 PF10498.4 CEP14430.1 - 0.18 10.4 17.0 0.77 8.4 11.8 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-Q PF13094.1 CEP14430.1 - 0.19 11.7 21.8 0.062 13.3 2.0 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Bacillus_HBL PF05791.6 CEP14430.1 - 0.19 11.0 12.6 0.65 9.3 5.7 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) YlqD PF11068.3 CEP14430.1 - 0.21 11.6 16.5 0.018 15.0 6.5 2.2 1 1 1 2 2 2 0 YlqD protein Striatin PF08232.7 CEP14430.1 - 0.23 11.7 14.5 0.56 10.5 10.1 1.7 1 1 0 1 1 1 0 Striatin family Vac_Fusion PF02346.11 CEP14430.1 - 0.23 10.9 6.6 0.23 10.8 0.4 2.9 1 1 3 4 4 4 0 Chordopoxvirus fusion protein AAA_27 PF13514.1 CEP14430.1 - 0.23 9.0 16.8 0.65 7.6 5.2 1.8 1 1 1 2 2 2 0 AAA domain Apolipoprotein PF01442.13 CEP14430.1 - 0.24 10.8 16.5 0.55 9.7 11.4 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prefoldin_3 PF13758.1 CEP14430.1 - 0.25 11.1 10.3 0.13 12.0 1.7 2.3 1 1 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.12 CEP14430.1 - 0.25 11.0 18.7 0.34 10.5 2.1 3.1 1 1 2 3 3 3 0 Prefoldin subunit DUF3450 PF11932.3 CEP14430.1 - 0.25 10.5 15.4 0.83 8.8 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.1 CEP14430.1 - 0.26 10.2 12.1 0.44 9.4 8.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FH2 PF02181.18 CEP14430.1 - 0.27 10.0 13.1 0.63 8.8 9.1 1.6 1 1 0 1 1 1 0 Formin Homology 2 Domain Seryl_tRNA_N PF02403.17 CEP14430.1 - 0.28 11.2 21.7 1.1 9.3 4.2 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nnf1 PF03980.9 CEP14430.1 - 0.28 11.1 14.8 0.21 11.5 4.1 2.5 1 1 0 2 2 2 0 Nnf1 FemAB PF02388.11 CEP14430.1 - 0.28 9.8 15.0 0.032 12.9 4.4 2.0 1 1 1 2 2 2 0 FemAB family HAUS-augmin3 PF14932.1 CEP14430.1 - 0.28 10.3 16.5 0.37 9.9 11.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DegS PF05384.6 CEP14430.1 - 0.28 10.3 14.5 0.035 13.3 3.7 2.1 1 1 1 2 2 2 0 Sensor protein DegS DUF342 PF03961.8 CEP14430.1 - 0.29 9.5 17.9 0.28 9.5 6.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) PspA_IM30 PF04012.7 CEP14430.1 - 0.29 10.4 17.4 1.3 8.3 6.5 2.4 1 1 1 2 2 2 0 PspA/IM30 family DUF904 PF06005.7 CEP14430.1 - 0.3 11.4 26.1 0.2 11.9 5.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF812 PF05667.6 CEP14430.1 - 0.31 9.4 17.5 0.46 8.9 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Transposase_22 PF02994.9 CEP14430.1 - 0.34 9.3 16.7 0.42 9.0 11.6 1.1 1 0 0 1 1 1 0 L1 transposable element Rootletin PF15035.1 CEP14430.1 - 0.36 10.7 17.2 0.55 10.1 12.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GP41 PF00517.12 CEP14430.1 - 0.38 10.2 6.6 0.41 10.1 2.6 2.0 1 1 1 2 2 2 0 Retroviral envelope protein Tektin PF03148.9 CEP14430.1 - 0.39 9.1 16.9 0.17 10.3 5.8 2.1 1 1 1 2 2 2 0 Tektin family Katanin_con80 PF13925.1 CEP14430.1 - 0.43 10.2 4.3 3.5 7.3 0.7 2.2 2 1 0 2 2 2 0 con80 domain of Katanin Adeno_PIX PF03955.9 CEP14430.1 - 0.43 11.1 7.9 1.5 9.3 1.5 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) TACC PF05010.9 CEP14430.1 - 0.48 10.1 15.9 1.3 8.7 11.0 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) TTKRSYEDQ PF10212.4 CEP14430.1 - 0.49 9.2 7.8 0.58 9.0 5.4 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF2802 PF10975.3 CEP14430.1 - 0.51 10.1 8.4 4.9 6.9 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) CALCOCO1 PF07888.6 CEP14430.1 - 0.53 8.5 16.0 0.69 8.1 11.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.14 CEP14430.1 - 0.53 8.0 15.9 1 7.1 11.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.7 CEP14430.1 - 0.54 10.0 15.8 3.1 7.5 5.8 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Corona_S2 PF01601.11 CEP14430.1 - 0.6 8.1 3.3 0.67 7.9 2.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ly49 PF08391.5 CEP14430.1 - 0.62 10.1 10.2 0.055 13.6 2.0 2.0 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region AKNA PF12443.3 CEP14430.1 - 0.64 10.0 11.7 0.48 10.4 0.6 3.0 1 1 2 3 3 3 0 AT-hook-containing transcription factor Ax_dynein_light PF10211.4 CEP14430.1 - 0.74 9.6 20.6 1.8 8.3 2.8 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain DUF4559 PF15112.1 CEP14430.1 - 0.75 8.9 13.1 0.21 10.7 4.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF4298 PF14131.1 CEP14430.1 - 0.77 9.6 10.5 3.2 7.6 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) Syntaxin PF00804.20 CEP14430.1 - 0.83 9.8 15.1 4.3 7.5 5.7 2.3 1 1 1 2 2 2 0 Syntaxin Nsp1_C PF05064.8 CEP14430.1 - 0.83 9.3 15.9 2.7 7.6 3.9 2.6 1 1 2 3 3 3 0 Nsp1-like C-terminal region Lipoprotein_20 PF13942.1 CEP14430.1 - 0.87 9.1 13.0 1.3 8.5 5.9 2.1 1 1 1 2 2 2 0 YfhG lipoprotein Allexi_40kDa PF05549.6 CEP14430.1 - 0.9 8.7 5.7 0.78 8.9 2.6 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein bZIP_1 PF00170.16 CEP14430.1 - 0.95 9.4 22.9 1.1 9.2 0.4 4.4 1 1 3 4 4 4 0 bZIP transcription factor GreA_GreB_N PF03449.10 CEP14430.1 - 0.97 9.5 12.9 0.62 10.1 4.0 3.6 1 1 2 3 3 3 0 Transcription elongation factor, N-terminal FlaC_arch PF05377.6 CEP14430.1 - 1.1 9.2 15.9 2.8 7.8 4.6 3.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Trehalase PF01204.13 CEP14430.1 - 1.3 7.6 7.6 1.5 7.3 5.2 1.0 1 0 0 1 1 1 0 Trehalase DUF1515 PF07439.6 CEP14430.1 - 1.3 8.8 7.9 6.4 6.6 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) PRKCSH-like PF12999.2 CEP14430.1 - 1.3 8.5 11.0 0.39 10.2 3.4 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like MtrG PF04210.8 CEP14430.1 - 1.4 8.6 9.2 0.97 9.1 0.7 3.2 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2894 PF11445.3 CEP14430.1 - 1.4 9.1 7.0 1.6 8.9 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Spc24 PF08286.6 CEP14430.1 - 1.5 8.5 20.7 1.2 8.8 4.1 2.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF724 PF05266.9 CEP14430.1 - 1.6 8.2 19.6 0.74 9.4 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DASH_Dam1 PF08653.5 CEP14430.1 - 1.7 8.4 4.7 73 3.2 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 PspB PF06667.7 CEP14430.1 - 1.8 8.5 10.8 0.32 10.9 0.3 3.0 2 2 1 3 3 3 0 Phage shock protein B DUF4600 PF15372.1 CEP14430.1 - 1.8 8.7 17.1 0.38 10.9 5.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DASH_Spc34 PF08657.5 CEP14430.1 - 1.8 8.1 16.3 5 6.7 10.4 2.3 1 1 1 2 2 2 0 DASH complex subunit Spc34 Lge1 PF11488.3 CEP14430.1 - 1.9 8.7 15.8 1.5 9.0 1.7 3.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Lectin_N PF03954.9 CEP14430.1 - 2 7.7 6.5 2.5 7.5 1.2 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain CDC37_N PF03234.9 CEP14430.1 - 2.2 8.5 16.4 5.5 7.2 11.4 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Phage_GP20 PF06810.6 CEP14430.1 - 2.2 7.6 23.3 4.3 6.7 5.7 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMCO5 PF14992.1 CEP14430.1 - 2.3 7.2 19.0 1 8.4 5.2 1.8 1 1 1 2 2 2 0 TMCO5 family AbiH PF14253.1 CEP14430.1 - 2.4 7.6 10.1 3.1 7.3 7.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Occludin_ELL PF07303.8 CEP14430.1 - 2.7 8.7 13.6 1.2e+02 3.4 9.5 2.7 1 1 0 1 1 1 0 Occludin homology domain BRE1 PF08647.6 CEP14430.1 - 2.7 8.0 20.1 0.36 10.8 6.6 2.2 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF972 PF06156.8 CEP14430.1 - 2.9 8.2 17.8 4.5 7.6 6.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AATF-Che1 PF13339.1 CEP14430.1 - 3.3 7.8 12.9 14 5.8 9.0 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Cob_adeno_trans PF01923.13 CEP14430.1 - 3.5 7.3 8.5 2.6 7.8 3.6 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Enkurin PF13864.1 CEP14430.1 - 3.6 7.8 17.3 2.4 8.3 9.5 2.1 1 1 1 2 2 2 0 Calmodulin-binding DUF4337 PF14235.1 CEP14430.1 - 3.9 7.2 17.8 2.4 7.9 4.8 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) YgaB PF14182.1 CEP14430.1 - 4.4 7.6 14.0 2 8.6 1.6 2.9 1 1 1 2 2 2 0 YgaB-like protein TMPIT PF07851.8 CEP14430.1 - 4.4 6.2 10.3 5.1 6.0 7.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4446 PF14584.1 CEP14430.1 - 4.6 7.0 12.0 8.6 6.1 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4140 PF13600.1 CEP14430.1 - 4.8 7.6 15.8 7.8 7.0 0.9 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) P4Ha_N PF08336.6 CEP14430.1 - 4.9 6.9 14.8 0.53 10.1 1.7 2.9 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4315 PF14193.1 CEP14430.1 - 5 7.1 24.2 0.61 10.0 0.3 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4315) Noelin-1 PF12308.3 CEP14430.1 - 5.3 6.8 7.2 21 4.9 0.3 2.6 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF4047 PF13256.1 CEP14430.1 - 6 6.8 14.8 5.3 7.0 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) DUF16 PF01519.11 CEP14430.1 - 7.2 6.8 16.0 3.4 7.9 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 CorA PF01544.13 CEP14430.1 - 7.6 5.4 8.7 13 4.7 6.0 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein OmpH PF03938.9 CEP14430.1 - 7.9 6.3 20.8 0.42 10.5 7.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.8 CEP14430.1 - 9.4 5.5 11.2 24 4.2 5.9 2.3 1 1 1 2 2 2 0 fzo-like conserved region LUC7 PF03194.10 CEP14430.1 - 9.4 5.6 13.4 8.8 5.7 8.7 1.4 1 1 0 1 1 1 0 LUC7 N_terminus Syntaxin-6_N PF09177.6 CEP14430.1 - 9.5 6.7 13.3 3.2e+02 1.8 8.1 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PEARLI-4 PF05278.7 CEP14430.1 - 9.6 5.4 15.9 18 4.6 11.1 1.4 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) GST_N_2 PF13409.1 CEP14431.1 - 5.6e-21 74.3 0.0 1.6e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEP14431.1 - 6.4e-13 48.3 0.0 3.8e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP14431.1 - 3.3e-08 33.4 0.1 6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CEP14431.1 - 2.4e-05 24.4 0.0 0.00044 20.4 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CEP14431.1 - 5e-05 23.7 0.0 0.00011 22.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2578 PF10843.3 CEP14431.1 - 0.028 14.1 0.1 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) Fasciclin PF02469.17 CEP14432.1 - 6.5e-80 265.4 0.0 1.9e-20 73.1 0.0 5.2 5 0 0 5 5 5 5 Fasciclin domain AA_permease_2 PF13520.1 CEP14433.1 - 1.8e-62 211.3 53.1 2.2e-62 211.0 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP14433.1 - 2.2e-25 88.9 44.2 3.3e-25 88.3 30.7 1.2 1 0 0 1 1 1 1 Amino acid permease SPRY PF00622.23 CEP14434.1 - 3.1e-17 62.8 0.0 5.4e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.1 CEP14434.1 - 3.8e-05 23.2 0.1 0.00013 21.5 0.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP14434.1 - 0.00011 22.1 0.4 0.00042 20.2 0.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP14434.1 - 0.004 16.7 1.4 0.017 14.7 0.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Peptidase_S8 PF00082.17 CEP14435.1 - 1.9e-43 148.6 4.0 3.5e-43 147.7 2.8 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CEP14435.1 - 0.0045 17.5 1.4 0.0094 16.4 1.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 RHH_3 PF12651.2 CEP14435.1 - 0.044 13.5 0.1 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain adh_short PF00106.20 CEP14437.1 - 1e-34 119.8 0.6 1.3e-34 119.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP14437.1 - 4.9e-19 69.0 0.1 6.5e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP14437.1 - 2.1e-14 53.6 0.5 2.8e-14 53.2 0.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CEP14437.1 - 7.5e-06 25.0 1.2 1.2e-05 24.3 0.8 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CEP14437.1 - 3.3e-05 23.9 1.0 6.7e-05 22.9 0.7 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CEP14437.1 - 0.00053 19.4 0.1 0.0014 18.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CEP14437.1 - 0.0024 17.5 0.1 0.0054 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 CEP14437.1 - 0.017 14.7 0.5 0.027 14.1 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GatB_Yqey PF02637.13 CEP14437.1 - 0.019 14.7 0.3 0.036 13.7 0.2 1.4 1 0 0 1 1 1 0 GatB domain Shikimate_DH PF01488.15 CEP14437.1 - 0.083 12.9 0.3 0.16 12.0 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UCH PF00443.24 CEP14438.1 - 1.7e-42 145.3 0.4 3.4e-42 144.4 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP14438.1 - 9.6e-17 61.3 4.6 1.6e-16 60.6 3.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF16 PF01519.11 CEP14438.1 - 0.47 10.7 4.6 0.1 12.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc24 PF08286.6 CEP14438.1 - 0.82 9.3 6.5 0.18 11.5 1.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF904 PF06005.7 CEP14438.1 - 2.7 8.3 10.6 0.26 11.5 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 CEP14438.1 - 3.4 7.8 8.7 2 8.5 2.8 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L38e PF01781.13 CEP14439.1 - 4e-34 116.1 3.4 4.3e-34 116.0 2.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_90kDa PF04494.10 CEP14439.1 - 0.0049 16.9 0.2 0.0052 16.8 0.1 1.1 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit CLTH PF10607.4 CEP14440.1 - 1.9e-19 69.7 0.1 2.1e-19 69.6 0.1 1.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Apc4 PF12896.2 CEP14440.1 - 0.041 13.1 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 UPF0270 PF06794.7 CEP14440.1 - 0.13 12.0 0.1 0.8 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Lipoprotein_17 PF04200.7 CEP14441.1 - 5 7.3 5.9 1.6 8.9 0.7 2.1 1 1 1 2 2 2 0 Lipoprotein associated domain W2 PF02020.13 CEP14442.1 - 9e-12 44.7 4.9 9e-12 44.7 3.4 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HALZ PF02183.13 CEP14442.1 - 0.017 14.7 0.1 0.049 13.3 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 CEP14442.1 - 0.15 11.9 1.9 11 5.8 0.1 2.7 2 0 0 2 2 2 0 Basic region leucine zipper Prp18 PF02840.10 CEP14444.1 - 1.4e-56 190.3 0.2 1.4e-56 190.3 0.1 2.4 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 CEP14444.1 - 1.6e-08 33.6 0.4 5.1e-08 32.0 0.2 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF3536 PF12055.3 CEP14444.1 - 0.0034 16.5 0.2 0.035 13.2 0.0 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF3536) AvrPphF-ORF-2 PF09143.5 CEP14444.1 - 0.064 12.9 0.8 0.33 10.6 0.1 2.2 2 1 0 2 2 2 0 AvrPphF-ORF-2 PEHE PF15275.1 CEP14444.1 - 1.1 9.7 12.5 0.1 13.0 4.9 2.1 2 1 0 2 2 2 0 PEHE domain DUF694 PF05107.7 CEP14444.1 - 1.6 7.8 9.2 3.5 6.7 6.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF694) RVT_1 PF00078.22 CEP14445.1 - 2.7e-14 53.0 0.0 4.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP14445.1 - 0.00044 20.4 0.3 0.00096 19.4 0.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GDPD PF03009.12 CEP14446.1 - 5.9e-28 98.0 0.0 1.3e-27 96.8 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CEP14446.1 - 0.019 15.1 0.4 0.019 15.1 0.3 2.2 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family DUF4460 PF14687.1 CEP14446.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DUF2042 PF09743.4 CEP14447.1 - 6.7e-20 71.5 2.6 1.6e-19 70.3 1.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2042) F-box PF00646.28 CEP14447.1 - 0.011 15.3 0.1 0.049 13.2 0.0 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 CEP14447.1 - 0.038 13.7 0.1 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like SH3_1 PF00018.23 CEP14448.1 - 7.4e-12 44.4 0.0 1.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP14448.1 - 4e-10 39.0 0.0 8.3e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CEP14448.1 - 5e-09 35.5 0.0 7.7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CEP14448.1 - 0.09 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain DUF4005 PF13178.1 CEP14449.1 - 0.34 11.1 4.4 0.76 10.0 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4005) Ras PF00071.17 CEP14450.1 - 8.3e-53 178.0 0.0 1.4e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Ras family FA_desaturase PF00487.19 CEP14450.1 - 2.8e-45 154.7 8.3 4.4e-45 154.1 5.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Miro PF08477.8 CEP14450.1 - 1.3e-16 61.1 0.0 7.4e-16 58.7 0.0 2.3 3 0 0 3 3 3 1 Miro-like protein Cyt-b5 PF00173.23 CEP14450.1 - 7.3e-15 54.5 0.2 3.2e-14 52.4 0.1 2.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arf PF00025.16 CEP14450.1 - 3.1e-10 39.5 0.0 5.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEP14450.1 - 0.0041 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP14450.1 - 0.098 12.0 0.0 0.35 10.2 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CEP14450.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TRAP-gamma PF07074.7 CEP14450.1 - 0.13 11.7 1.8 0.29 10.6 1.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) AAA_14 PF13173.1 CEP14450.1 - 0.14 12.0 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CEP14450.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ydc2-catalyt PF09159.5 CEP14451.1 - 2e-25 89.8 4.0 1.9e-13 50.5 0.0 3.1 1 1 2 3 3 3 3 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 CEP14451.1 - 3.5e-07 29.5 0.0 1.2e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 CEP14451.1 - 0.00093 19.0 0.0 0.048 13.5 0.0 2.5 2 0 0 2 2 2 1 Poxvirus A22 protein Rho_N PF07498.7 CEP14451.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Phytoreo_P8 PF07124.6 CEP14451.1 - 0.036 12.7 0.1 0.054 12.1 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Cir_N PF10197.4 CEP14451.1 - 0.6 10.1 2.2 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR RPE65 PF03055.10 CEP14452.1 - 1.9e-97 326.8 0.3 2.3e-97 326.5 0.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF4544 PF15077.1 CEP14453.1 - 0.04 13.4 1.0 0.048 13.1 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DUF3138 PF11336.3 CEP14453.1 - 2.4 6.2 8.9 2.6 6.1 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DnaJ PF00226.26 CEP14454.1 - 1.8e-20 72.4 1.9 1.8e-20 72.4 1.4 2.0 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CEP14454.1 - 7.4e-20 70.6 0.4 1.3e-18 66.6 0.1 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CEP14454.1 - 2.4e-17 62.7 14.8 4.5e-17 61.8 10.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Amidohydro_4 PF13147.1 CEP14455.1 - 6.5e-09 36.2 0.0 7.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CEP14455.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CEP14455.1 - 0.007 15.6 0.0 0.0099 15.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family ComZ PF10815.3 CEP14455.1 - 0.064 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 ComZ UBN2 PF14223.1 CEP14456.1 - 0.044 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type AF0941-like PF14591.1 CEP14456.1 - 0.048 13.7 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 AF0941-like Metallophos PF00149.23 CEP14457.1 - 2.1e-44 151.3 0.2 3.3e-44 150.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase APC10 PF03256.11 CEP14457.1 - 3.4e-36 124.6 0.3 1.9e-22 79.8 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) BUD22 PF09073.5 CEP14457.1 - 0.0019 17.3 8.4 0.0027 16.8 5.8 1.1 1 0 0 1 1 1 1 BUD22 IL22 PF14565.1 CEP14459.1 - 0.028 14.5 0.5 0.4 10.7 0.0 2.0 1 1 1 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Tantalus PF15386.1 CEP14459.1 - 0.035 13.8 0.5 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 Drosophila Tantalus-like DUF4611 PF15387.1 CEP14459.1 - 1.5 8.9 5.9 2 8.6 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) OrfB_Zn_ribbon PF07282.6 CEP14460.1 - 0.087 12.4 0.2 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Y_phosphatase PF00102.22 CEP14461.1 - 2.8e-09 36.6 0.0 1.3e-05 24.6 0.0 2.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 CEP14461.1 - 9.5e-06 25.2 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CEP14461.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate SAM_2 PF07647.12 CEP14462.1 - 1.5e-08 34.3 0.2 3.5e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEP14462.1 - 6.2e-06 26.3 0.1 1.6e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MTHFR PF02219.12 CEP14463.1 - 7.4e-107 356.7 0.0 1e-106 356.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_23 PF13489.1 CEP14464.1 - 1.9e-08 34.2 0.0 3.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP14464.1 - 3e-08 33.4 0.0 5.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP14464.1 - 2e-07 31.5 0.0 3.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP14464.1 - 1.3e-06 27.5 0.3 0.00012 21.1 0.0 2.6 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_11 PF08241.7 CEP14464.1 - 1.9e-06 28.2 0.0 5.4e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP14464.1 - 0.00016 22.1 0.0 0.00067 20.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP14464.1 - 0.00022 20.3 0.0 0.0007 18.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEP14464.1 - 0.00058 20.1 0.0 0.0023 18.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ribosomal_S8 PF00410.14 CEP14464.1 - 0.021 14.6 0.3 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S8 Methyltransf_8 PF05148.10 CEP14464.1 - 0.062 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase MULE PF10551.4 CEP14465.1 - 0.0043 17.1 0.4 0.023 14.8 0.3 2.1 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.12 CEP14465.1 - 0.0044 16.4 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Sec5 PF15469.1 CEP14467.1 - 0.0035 17.0 5.1 0.074 12.7 0.3 3.3 2 1 0 2 2 2 2 Exocyst complex component Sec5 Frag1 PF10277.4 CEP14470.1 - 1.4e-39 135.8 15.1 1.4e-39 135.8 10.5 3.4 3 0 0 3 3 3 3 Frag1/DRAM/Sfk1 family PI3Ka PF00613.15 CEP14473.1 - 9e-59 197.7 0.1 1.7e-58 196.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CEP14473.1 - 6e-50 169.8 0.1 9.6e-49 165.9 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CEP14473.1 - 5.3e-38 130.0 0.1 1.2e-37 128.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 NMO PF03060.10 CEP14474.1 - 1.9e-66 224.4 0.3 3.7e-66 223.5 0.2 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CEP14474.1 - 2.8e-10 39.6 0.1 1.2e-05 24.3 0.6 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 CEP14474.1 - 0.00024 20.1 0.6 0.0047 15.9 0.0 2.4 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 CEP14474.1 - 0.0059 15.4 0.3 0.011 14.5 0.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CEP14474.1 - 0.012 14.8 0.3 0.17 11.1 0.1 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.12 CEP14474.1 - 0.023 13.6 0.2 0.047 12.5 0.1 1.6 2 0 0 2 2 2 0 Conserved region in glutamate synthase GCR1_C PF12550.3 CEP14475.1 - 1e-11 44.5 0.1 1.6e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF3269 PF11673.3 CEP14476.1 - 0.12 12.8 0.3 0.48 10.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3269) DUF4218 PF13960.1 CEP14481.1 - 0.052 13.0 0.7 0.37 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) DDE_3 PF13358.1 CEP14482.1 - 8.3e-13 48.3 0.0 9.8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease GnsAB PF08178.6 CEP14482.1 - 0.15 11.7 0.1 6.1 6.5 0.0 2.2 2 0 0 2 2 2 0 GnsA/GnsB family PepSY_2 PF13670.1 CEP14484.1 - 1e-06 28.5 0.7 5.7 6.9 0.0 5.9 4 1 2 6 6 6 3 Peptidase propeptide and YPEB domain DUF866 PF05907.8 CEP14484.1 - 0.59 9.6 15.7 13 5.2 0.1 4.9 2 2 3 5 5 5 0 Eukaryotic protein of unknown function (DUF866) Hepar_II_III PF07940.8 CEP14485.1 - 0.067 13.0 0.1 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Heparinase II/III-like protein Mto2_bdg PF12808.2 CEP14486.1 - 0.033 14.2 1.5 0.069 13.2 0.0 2.2 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GATA PF00320.22 CEP14487.1 - 9.8e-16 56.8 3.9 9.8e-16 56.8 2.7 2.1 2 0 0 2 2 2 1 GATA zinc finger Lzipper-MIP1 PF14389.1 CEP14487.1 - 0.0035 17.4 0.1 0.011 15.8 0.1 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 TF_Zn_Ribbon PF08271.7 CEP14487.1 - 0.053 12.8 0.8 0.13 11.5 0.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding RRN7 PF11781.3 CEP14487.1 - 0.055 12.9 1.1 0.14 11.6 0.7 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 HNH_5 PF14279.1 CEP14487.1 - 0.094 12.7 1.8 0.14 12.1 0.0 2.3 3 0 0 3 3 3 0 HNH endonuclease Asn_synthase PF00733.16 CEP14488.1 - 2.3e-73 246.8 0.0 3.4e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CEP14488.1 - 4.7e-39 132.9 0.0 9.8e-39 131.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CEP14488.1 - 1.9e-32 111.9 0.0 1.1e-31 109.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CEP14488.1 - 7.2e-09 35.1 0.0 1.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 CEP14488.1 - 3.7e-07 29.1 0.0 0.019 13.6 0.0 3.2 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 CEP14488.1 - 0.0016 17.4 0.1 0.0073 15.2 0.0 2.2 2 1 0 2 2 2 1 NAD synthase DUF2939 PF11159.3 CEP14488.1 - 0.027 14.6 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) QueC PF06508.8 CEP14488.1 - 0.086 12.1 0.1 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PepSY_2 PF13670.1 CEP14489.1 - 0.0072 16.1 0.4 3.4 7.6 0.0 3.0 2 1 1 3 3 3 2 Peptidase propeptide and YPEB domain SASP_gamma PF04259.9 CEP14489.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.9 2 1 2 4 4 4 0 Small, acid-soluble spore protein, gamma-type UDPGT PF00201.13 CEP14491.1 - 0.021 13.3 0.0 0.39 9.2 0.0 2.0 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Sec63 PF02889.11 CEP14492.1 - 1.4e-53 182.2 0.1 1.9e-53 181.7 0.1 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 CEP14492.1 - 3.3e-22 77.9 0.8 7.8e-22 76.7 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain SH3_1 PF00018.23 CEP14493.1 - 3.5e-12 45.5 0.0 8e-12 44.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PX PF00787.19 CEP14493.1 - 4.2e-07 29.7 0.0 8.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 CEP14493.1 - 7.7e-06 25.4 0.0 1.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PB1 PF00564.19 CEP14493.1 - 0.0089 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Rho_GDI PF02115.12 CEP14494.1 - 1.1e-43 149.0 1.7 9.9e-27 93.6 0.2 2.0 1 1 1 2 2 2 2 RHO protein GDP dissociation inhibitor PduL PF06130.7 CEP14494.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Propanediol utilisation protein PduL LMBR1 PF04791.11 CEP14495.1 - 0.013 14.0 0.5 0.015 13.9 0.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein OppC_N PF12911.2 CEP14495.1 - 0.92 8.9 3.7 1.1 8.7 1.6 1.8 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3316 PF11777.3 CEP14496.1 - 0.012 15.4 0.3 0.018 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) HoxA13_N PF12284.3 CEP14496.1 - 0.013 15.6 0.5 0.015 15.4 0.4 1.1 1 0 0 1 1 1 0 Hox protein A13 N terminal Alpha_GJ PF03229.8 CEP14496.1 - 0.24 11.7 2.9 0.27 11.5 2.0 1.1 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF1986 PF09342.6 CEP14497.1 - 0.047 12.9 0.4 0.085 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Es2 PF09751.4 CEP14498.1 - 3.3e-69 234.3 8.5 7e-52 177.2 3.2 2.0 1 1 1 2 2 2 2 Nuclear protein Es2 Acyl_transf_1 PF00698.16 CEP14499.1 - 3.7e-62 210.5 0.0 1.9e-61 208.1 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CEP14499.1 - 2.8e-31 107.4 0.1 1.1e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 CEP14499.1 - 6.6e-29 99.4 0.3 2e-28 97.9 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) ketoacyl-synt PF00109.21 CEP14499.1 - 2.1e-17 63.4 0.3 7.5e-17 61.6 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 CEP14499.1 - 1.6e-16 60.1 0.0 3.9e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 CEP14499.1 - 2.3e-09 37.0 0.0 6.5e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 CEP14499.1 - 0.2 11.9 0.1 8.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Phosphopantetheine attachment site Ribosomal_S21 PF01165.15 CEP14500.1 - 0.11 11.9 0.3 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S21 DcpS_C PF11969.3 CEP14501.1 - 0.076 13.2 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Fucose_iso_N2 PF07882.7 CEP14501.1 - 0.092 12.3 1.0 0.12 11.9 0.7 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF3450 PF11932.3 CEP14501.1 - 0.11 11.7 1.6 0.17 11.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2115 PF09888.4 CEP14501.1 - 0.12 12.4 1.2 0.2 11.7 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) UCR_TM PF02921.9 CEP14502.1 - 1.9e-20 72.8 1.5 4.5e-20 71.6 1.0 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CEP14502.1 - 1.9e-17 62.6 0.1 3.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Transp_cyt_pur PF02133.10 CEP14502.1 - 0.09 11.3 0.2 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1691 PF07950.6 CEP14503.1 - 9e-19 67.4 1.5 2.4e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 CEP14503.1 - 0.00055 19.7 0.5 0.00055 19.7 0.3 2.4 1 1 1 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ferric_reduct PF01794.14 CEP14503.1 - 0.056 13.5 5.4 0.12 12.4 1.3 2.6 1 1 1 2 2 2 0 Ferric reductase like transmembrane component SecY PF00344.15 CEP14504.1 - 5.3e-92 308.3 12.6 6.9e-92 308.0 8.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CEP14504.1 - 5.4e-18 64.2 0.4 1.3e-17 62.9 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p RseC_MucC PF04246.7 CEP14504.1 - 0.42 10.1 2.1 0.49 9.9 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3940 PF13076.1 CEP14506.1 - 0.3 10.6 0.2 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) Polysacc_deac_1 PF01522.16 CEP14507.1 - 4.3e-23 81.2 0.0 9.4e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Bacillus_HBL PF05791.6 CEP14508.1 - 0.11 11.9 5.8 1.1 8.6 4.0 2.2 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2992 PF11208.3 CEP14508.1 - 0.7 9.8 9.0 0.11 12.4 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) GWT1 PF06423.7 CEP14509.1 - 3.4e-36 124.3 5.1 3.4e-36 124.3 3.6 3.0 4 1 1 5 5 5 1 GWT1 SNF2_N PF00176.18 CEP14510.1 - 2.2e-74 249.9 2.1 4.5e-74 248.9 1.4 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 CEP14510.1 - 1.7e-22 78.8 4.5 4.7e-12 45.3 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CEP14510.1 - 1.5e-15 56.7 0.0 4.7e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 CEP14510.1 - 2.5e-15 56.5 0.0 2.5e-15 56.5 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) DUF4078 PF13300.1 CEP14511.1 - 2.2e-21 75.7 11.7 2.2e-21 75.7 8.1 3.4 2 2 1 4 4 4 1 Domain of unknown function (DUF4078) DUF1640 PF07798.6 CEP14513.1 - 0.028 14.4 0.5 0.035 14.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) rve PF00665.21 CEP14516.1 - 1.3e-17 63.9 0.0 1.1e-16 61.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CEP14516.1 - 2.3e-10 39.9 0.2 6e-10 38.6 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP14516.1 - 9.8e-05 21.6 1.5 9.8e-05 21.6 1.0 2.2 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 CEP14516.1 - 0.0003 21.2 0.0 0.00082 19.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP14516.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1104 PF06518.6 CEP14518.1 - 0.0018 18.3 1.6 0.27 11.3 0.1 3.3 2 2 1 3 3 3 1 Protein of unknown function (DUF1104) Tropomyosin_1 PF12718.2 CEP14518.1 - 0.034 13.9 4.1 0.052 13.3 2.8 1.3 1 0 0 1 1 1 0 Tropomyosin like CCDC-167 PF15188.1 CEP14518.1 - 0.035 14.0 3.7 0.061 13.2 1.7 2.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 CEP14518.1 - 0.069 12.7 3.7 0.092 12.3 2.6 1.2 1 0 0 1 1 1 0 IncA protein ArsA_ATPase PF02374.10 CEP14518.1 - 0.11 11.4 0.8 0.18 10.8 0.6 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase Mannitol_dh PF01232.18 CEP14518.1 - 0.13 12.2 1.6 0.41 10.5 0.3 1.8 1 1 1 2 2 2 0 Mannitol dehydrogenase Rossmann domain YlbD_coat PF14071.1 CEP14518.1 - 0.16 12.0 1.9 0.43 10.6 1.3 1.7 1 0 0 1 1 1 0 Putative coat protein TBPIP PF07106.8 CEP14518.1 - 0.41 10.1 7.0 0.57 9.7 4.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 CEP14518.1 - 0.59 9.5 8.0 0.43 10.0 4.7 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 CEP14518.1 - 3 7.8 7.5 7.7 6.5 5.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor zf-CCHC PF00098.18 CEP14519.1 - 1.3e-05 24.9 2.9 2.7e-05 23.8 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle TH1 PF04858.8 CEP14521.1 - 1e-80 271.5 1.6 1.3e-80 271.2 1.1 1.0 1 0 0 1 1 1 1 TH1 protein Chromo PF00385.19 CEP14522.1 - 1.4e-08 34.2 1.6 2.6e-08 33.4 1.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP14522.1 - 0.018 14.6 0.2 0.04 13.6 0.1 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain HTH_28 PF13518.1 CEP14523.1 - 0.0078 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP14523.1 - 0.0086 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 CEP14523.1 - 0.018 14.6 0.4 0.031 13.9 0.3 1.3 1 0 0 1 1 1 0 Transposase DUF2481 PF10654.4 CEP14523.1 - 0.033 13.8 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) HTH_17 PF12728.2 CEP14523.1 - 0.062 13.5 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 CEP14524.1 - 1.5e-24 86.3 0.0 1.8e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP14524.1 - 0.023 13.8 0.1 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease MFS_1 PF07690.11 CEP14526.1 - 1e-46 159.2 27.4 1e-46 159.2 19.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily URO-D PF01208.12 CEP14527.1 - 2.5e-125 417.9 0.0 2.8e-125 417.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Glyco_hydro_3 PF00933.16 CEP14528.1 - 6.1e-86 288.0 0.2 8.5e-86 287.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CEP14528.1 - 2.3e-67 226.8 0.0 4.6e-67 225.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CEP14528.1 - 1.4e-20 72.9 0.1 2.7e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain C9orf72-like PF15019.1 CEP14529.1 - 5.3e-08 32.3 0.1 0.0029 16.8 0.0 2.3 1 1 1 2 2 2 2 C9orf72-like protein family 6PF2K PF01591.13 CEP14530.1 - 8.1e-61 204.9 0.4 8.1e-61 204.9 0.3 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEP14530.1 - 5e-25 88.4 2.0 1.4e-24 87.0 0.8 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CEP14530.1 - 0.0038 17.0 1.1 0.0063 16.4 0.1 1.9 2 0 0 2 2 2 1 AAA domain DUF1863 PF08937.6 CEP14531.1 - 0.091 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF3441 PF11923.3 CEP14532.1 - 1.6e-29 101.7 0.1 1.6e-29 101.7 0.1 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 CEP14532.1 - 1.2e-22 79.6 0.1 3.6e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) eIF-3c_N PF05470.7 CEP14533.1 - 1.1e-176 588.5 26.8 2.7e-143 478.2 0.8 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CEP14533.1 - 2e-15 56.9 0.1 6.3e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain EMP24_GP25L PF01105.19 CEP14534.1 - 2.1e-48 164.4 1.0 2.4e-48 164.2 0.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4337 PF14235.1 CEP14534.1 - 0.067 13.0 0.2 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PPC PF04151.10 CEP14534.1 - 0.099 13.6 0.3 0.21 12.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain F-box-like PF12937.2 CEP14535.1 - 4.4e-07 29.5 0.0 1.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 CEP14536.1 - 1.2e-07 31.2 2.3 1.5e-07 31.0 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP14536.1 - 4e-05 23.1 0.1 0.0001 21.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain Homez PF11569.3 CEP14536.1 - 0.00026 19.9 0.1 0.00026 19.9 0.1 2.1 3 0 0 3 3 3 1 Homeodomain leucine-zipper encoding, Homez Thiolase_N PF00108.18 CEP14538.1 - 8e-83 277.4 4.2 2.3e-82 275.9 1.8 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEP14538.1 - 5.8e-47 158.1 0.1 1.1e-46 157.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain HisKA_2 PF07568.7 CEP14539.1 - 0.017 14.9 0.0 0.74 9.7 0.0 2.6 3 0 0 3 3 3 0 Histidine kinase Mo25 PF08569.6 CEP14540.1 - 8.8e-126 419.4 19.8 2.3e-125 418.1 13.7 1.6 1 1 0 1 1 1 1 Mo25-like Lipocalin_7 PF14651.1 CEP14540.1 - 0.06 13.0 0.1 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family DUF544 PF04424.8 CEP14540.1 - 0.37 10.6 10.1 1.4 8.7 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF544) GYF PF02213.11 CEP14541.1 - 6.9e-18 63.9 0.1 1.8e-17 62.6 0.1 1.8 1 0 0 1 1 1 1 GYF domain RVT_1 PF00078.22 CEP14543.1 - 4e-09 36.1 0.5 1.2e-06 27.9 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP14545.1 - 2e-17 63.3 0.1 5.8e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 CEP14545.1 - 4.8e-05 23.0 0.4 4.8e-05 23.0 0.3 2.9 4 1 0 4 4 4 1 Phage integrase family PIF1 PF05970.9 CEP14546.1 - 8.5e-42 143.3 0.0 1e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Fe-S_biosyn PF01521.15 CEP14548.1 - 6.4e-20 71.1 0.0 8.5e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SET PF00856.23 CEP14549.1 - 9.9e-23 81.2 2.7 1.6e-22 80.5 0.0 2.9 3 1 0 3 3 3 1 SET domain WW PF00397.21 CEP14549.1 - 7.5e-08 32.1 1.6 7.5e-08 32.1 1.1 2.0 2 0 0 2 2 2 1 WW domain SRI PF08236.6 CEP14549.1 - 2.6e-06 27.2 3.8 2.6e-06 27.2 2.7 2.3 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Nucleoplasmin PF03066.10 CEP14549.1 - 0.007 15.8 4.7 0.007 15.8 3.3 2.5 2 0 0 2 2 2 1 Nucleoplasmin PQQ PF01011.16 CEP14549.1 - 0.15 11.6 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat Mak16 PF04874.9 CEP14549.1 - 2.9 8.0 15.8 6.3 6.9 1.1 2.9 2 0 0 2 2 2 0 Mak16 protein C-terminal region Spt5_N PF11942.3 CEP14549.1 - 3.6 8.2 23.4 1.8 9.1 8.9 3.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Glyco_hydro_47 PF01532.15 CEP14550.1 - 3.7e-144 480.7 0.2 4.7e-144 480.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 CEP14550.1 - 1.9e-11 43.5 0.0 3.8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 PA domain LNS2 PF08235.8 CEP14551.1 - 6.2e-69 230.5 0.0 1.2e-68 229.6 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CEP14551.1 - 7e-39 131.9 0.1 1.3e-38 131.0 0.1 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 CEP14551.1 - 0.019 14.8 0.3 0.019 14.8 0.2 4.3 6 0 0 6 6 6 0 Drug resistance and apoptosis regulator eIF-1a PF01176.14 CEP14554.1 - 1.3e-13 50.1 0.1 1.7e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Oxidored_FMN PF00724.15 CEP14555.1 - 1.4e-105 353.0 0.0 1.6e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family zf-DHHC PF01529.15 CEP14556.1 - 2.2e-11 43.4 7.0 2.9e-11 43.0 4.9 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase LLC1 PF14945.1 CEP14556.1 - 0.02 15.2 0.2 0.034 14.4 0.2 1.3 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DZR PF12773.2 CEP14556.1 - 0.082 12.7 7.8 0.13 12.1 5.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 CEP14556.1 - 1.3 8.9 12.2 2.2 8.2 8.4 1.5 1 1 0 1 1 1 0 FYVE zinc finger RhoGEF PF00621.15 CEP14557.1 - 3.5e-37 128.0 6.2 3.5e-37 128.0 4.3 2.9 3 1 0 3 3 3 1 RhoGEF domain eIF-5a PF01287.15 CEP14557.1 - 1.3e-26 92.2 0.5 1.3e-26 92.2 0.3 3.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold BAR PF03114.13 CEP14557.1 - 6.2e-13 48.7 5.7 2.2e-12 46.9 3.9 2.0 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 CEP14557.1 - 5.1e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain KOW PF00467.24 CEP14557.1 - 0.001 18.7 0.5 0.003 17.2 0.4 1.8 1 0 0 1 1 1 1 KOW motif TruB_N PF01509.13 CEP14557.1 - 0.083 13.0 1.2 12 6.0 0.1 3.4 2 1 1 3 3 3 0 TruB family pseudouridylate synthase (N terminal domain) CtaG_Cox11 PF04442.9 CEP14558.1 - 2.3e-58 196.3 0.1 2.9e-58 195.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RhoGAP PF00620.22 CEP14559.1 - 9.4e-39 132.4 1.2 9.4e-39 132.4 0.8 2.1 2 0 0 2 2 2 1 RhoGAP domain PDEase_II PF02112.10 CEP14563.1 - 0.041 12.8 0.1 0.065 12.1 0.1 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II rve PF00665.21 CEP14566.1 - 2.8e-05 24.1 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 CEP14566.1 - 0.01 15.2 0.7 0.031 13.7 0.2 1.9 2 0 0 2 2 2 0 Integrase Zinc binding domain DNA_pol_A_exo1 PF01612.15 CEP14567.1 - 7.1e-05 22.3 0.0 0.00023 20.7 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease rve PF00665.21 CEP14569.1 - 8.1e-19 67.8 0.0 1.4e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP14569.1 - 0.024 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_IS240 PF13610.1 CEP14569.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 DDE domain Chromo PF00385.19 CEP14571.1 - 1.2e-07 31.3 0.2 1.9e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TRSP PF12500.3 CEP14571.1 - 0.058 12.8 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 TRSP domain C terminus to PRTase_2 Transposase_21 PF02992.9 CEP14574.1 - 1.5e-05 24.2 0.0 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Interfer-bind PF09294.5 CEP14574.1 - 0.21 11.6 0.2 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF3712 PF12505.3 CEP14575.1 - 6.6e-67 223.2 40.0 5.3e-22 78.1 0.3 8.4 7 1 1 8 8 8 4 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CEP14575.1 - 4e-15 56.0 12.9 0.0014 18.9 0.1 7.8 7 0 0 7 7 7 4 Late embryogenesis abundant protein Rifin_STEVOR PF02009.11 CEP14575.1 - 0.009 15.6 7.2 0.16 11.5 0.0 2.3 2 0 0 2 2 2 2 Rifin/stevor family Shisa PF13908.1 CEP14575.1 - 3.8 7.6 7.3 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ICAM_N PF03921.9 CEP14576.1 - 0.033 13.6 0.1 0.089 12.2 0.0 1.7 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain Metallophos PF00149.23 CEP14577.1 - 8.9e-07 28.4 2.4 8.9e-07 28.4 1.7 2.5 2 2 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP14577.1 - 0.0038 17.0 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PQ-loop PF04193.9 CEP14578.1 - 4.5e-16 58.1 1.7 4.5e-16 58.1 1.2 2.7 3 1 1 4 4 4 1 PQ loop repeat ER_lumen_recept PF00810.13 CEP14578.1 - 0.0038 17.7 1.2 0.0038 17.7 0.8 2.4 2 1 0 2 2 2 1 ER lumen protein retaining receptor 2-oxoacid_dh PF00198.18 CEP14579.1 - 3.4e-83 278.4 0.0 4.5e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CEP14579.1 - 1.3e-17 63.1 0.5 3.1e-17 61.9 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CEP14579.1 - 2.4e-11 43.0 0.5 2.4e-11 43.0 0.3 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CEP14579.1 - 0.036 13.7 0.2 9.8 5.9 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like Ribosomal_60s PF00428.14 CEP14579.1 - 0.4 11.1 11.4 0.08 13.3 3.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein GATA PF00320.22 CEP14580.1 - 6e-32 108.7 20.3 4.4e-16 57.9 4.0 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CEP14580.1 - 2.8e-06 26.5 6.6 0.0077 15.5 0.6 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 CEP14580.1 - 0.0011 18.4 6.8 0.096 12.2 0.4 2.6 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 TPR_16 PF13432.1 CEP14580.1 - 0.18 12.4 2.2 0.3 11.8 1.5 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn-ribbon_8 PF09723.5 CEP14580.1 - 0.48 10.4 5.1 9.5 6.2 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 CEP14580.1 - 0.58 9.8 6.4 1.2 8.8 0.5 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-CHY PF05495.7 CEP14580.1 - 0.72 10.0 8.2 0.98 9.6 2.5 2.5 2 0 0 2 2 2 0 CHY zinc finger OrfB_Zn_ribbon PF07282.6 CEP14580.1 - 0.88 9.2 12.5 1 9.0 0.5 3.2 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.10 CEP14580.1 - 1.5 8.4 7.4 0.58 9.7 0.7 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Auto_anti-p27 PF06677.7 CEP14580.1 - 2.7 7.8 6.0 13 5.5 0.2 3.1 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mst1_SARAH PF11629.3 CEP14581.1 - 0.4 10.5 3.6 4.2 7.2 0.1 2.8 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 PBP PF01161.15 CEP14582.1 - 4.2e-21 75.3 0.1 6.3e-19 68.2 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ras PF00071.17 CEP14583.1 - 6.9e-59 197.8 0.3 8.3e-59 197.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP14583.1 - 1.5e-21 77.0 0.0 3.2e-21 76.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP14583.1 - 5.8e-15 54.9 0.0 7.2e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP14583.1 - 1.4e-08 34.2 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP14583.1 - 2.7e-07 30.1 0.1 4.7e-07 29.4 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP14583.1 - 2.3e-06 27.5 0.0 7.6e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CEP14583.1 - 0.0016 18.4 0.1 0.006 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CEP14583.1 - 0.0034 16.5 0.4 0.011 14.9 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP14583.1 - 0.0065 16.6 0.1 0.034 14.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain Zn_clus PF00172.13 CEP14584.1 - 9.4e-09 35.0 8.1 1.6e-08 34.3 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDHD PF02862.12 CEP14585.1 - 7.3e-14 52.1 5.1 2.2e-13 50.5 3.5 1.8 1 1 0 1 1 1 1 DDHD domain IncA PF04156.9 CEP14585.1 - 0.034 13.7 4.1 0.035 13.7 2.3 1.5 1 1 0 1 1 1 0 IncA protein NDUFA12 PF05071.11 CEP14585.1 - 0.19 12.2 2.2 0.64 10.5 0.0 2.3 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 FBPase PF00316.15 CEP14586.1 - 6.8e-126 419.4 0.0 7.6e-126 419.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase HLH PF00010.21 CEP14587.1 - 1.4e-13 50.2 0.6 1.4e-13 50.2 0.4 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Med9 PF07544.8 CEP14587.1 - 9.2 6.0 16.3 9.7 6.0 2.4 3.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 VTC PF09359.5 CEP14588.1 - 4.1e-86 288.5 0.1 7.7e-86 287.6 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEP14588.1 - 3.5e-20 72.9 12.5 3.1e-10 40.3 1.5 3.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 CEP14588.1 - 4.6e-11 42.7 3.2 1e-10 41.6 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) JAB PF01398.16 CEP14589.1 - 2.2e-35 120.8 0.0 4.7e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CEP14589.1 - 7e-30 103.4 3.4 3.2e-29 101.3 2.8 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CEP14589.1 - 6.5e-08 32.0 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MbeB_N PF04837.7 CEP14589.1 - 0.14 12.3 1.3 0.29 11.2 0.9 1.5 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Mito_carr PF00153.22 CEP14590.1 - 2.4e-49 165.0 5.5 2.9e-16 58.9 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2062 PF09835.4 CEP14590.1 - 2.5 7.6 5.0 18 4.9 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) Med6 PF04934.9 CEP14591.1 - 1.3e-23 83.1 0.1 2.1e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Pho88 PF10032.4 CEP14592.1 - 1.1e-28 99.7 0.5 4e-25 88.1 0.1 2.0 1 1 1 2 2 2 2 Phosphate transport (Pho88) GntP_permease PF02447.11 CEP14592.1 - 0.089 11.2 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 GntP family permease DUF3784 PF12650.2 CEP14592.1 - 0.78 9.7 3.9 1.3 9.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) RVT_1 PF00078.22 CEP14593.1 - 2.1e-09 37.0 0.1 7.8e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_29 PF13551.1 CEP14594.1 - 8.8e-09 35.4 0.1 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 CEP14594.1 - 3.5e-08 33.1 2.6 1.3e-05 24.9 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.13 CEP14594.1 - 1.4e-06 28.2 1.4 1.7e-06 27.9 0.3 1.6 2 0 0 2 2 1 1 Transposase TrmB PF01978.14 CEP14594.1 - 1.7e-05 24.3 0.2 0.00047 19.8 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.1 CEP14594.1 - 0.0001 22.2 0.0 0.00087 19.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 CEP14594.1 - 0.00013 21.4 0.3 0.00039 19.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP14594.1 - 0.00095 18.7 0.0 0.044 13.4 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 CEP14594.1 - 0.0037 18.0 0.6 0.0087 16.8 0.3 1.6 1 1 1 2 2 2 1 Homeodomain-like domain PAX PF00292.13 CEP14594.1 - 0.017 14.8 0.3 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 'Paired box' domain HTH_24 PF13412.1 CEP14594.1 - 0.024 14.0 0.1 0.71 9.3 0.0 2.7 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_1 PF11427.3 CEP14594.1 - 0.039 13.5 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase HTH_11 PF08279.7 CEP14594.1 - 0.06 13.0 1.0 2.7 7.6 0.0 2.6 3 0 0 3 3 3 0 HTH domain DUF3294 PF07957.6 CEP14594.1 - 0.1 12.1 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Mor PF08765.6 CEP14594.1 - 0.13 12.0 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Mor transcription activator family CENP-B_N PF04218.8 CEP14594.1 - 0.14 11.6 0.3 0.54 9.7 0.0 2.0 2 1 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HLH PF00010.21 CEP14595.1 - 2.6e-19 68.6 0.7 1.4e-18 66.2 0.1 2.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2215 PF10225.4 CEP14595.1 - 5 6.4 6.7 20 4.5 4.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) DUF2181 PF10223.4 CEP14596.1 - 0.079 12.2 0.2 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) DUF2811 PF10929.3 CEP14597.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) HATPase_c_3 PF13589.1 CEP14597.1 - 0.14 11.8 0.4 0.2 11.3 0.3 1.4 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VPS9 PF02204.13 CEP14599.1 - 4e-23 81.4 0.2 9.5e-23 80.2 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HeLo PF14479.1 CEP14599.1 - 0.018 14.7 2.7 0.03 14.0 0.8 2.1 2 0 0 2 2 2 0 Prion-inhibition and propagation Hid1 PF12722.2 CEP14600.1 - 0.5 7.9 35.3 0.65 7.5 24.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF605 PF04652.11 CEP14600.1 - 9.6 5.4 40.2 11 5.2 27.9 1.2 1 0 0 1 1 1 0 Vta1 like DUF605 PF04652.11 CEP14601.1 - 0.21 10.9 37.3 0.25 10.7 25.8 1.2 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 CEP14601.1 - 0.36 8.4 35.0 0.49 8.0 24.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 CEP14601.1 - 0.37 9.2 42.0 0.43 8.9 29.1 1.2 1 0 0 1 1 1 0 Daxx Family FAM196 PF15265.1 CEP14601.1 - 2.6 7.1 36.0 3.1 6.9 24.9 1.1 1 0 0 1 1 1 0 FAM196 family Utp14 PF04615.8 CEP14601.1 - 7.9 4.5 41.5 10 4.1 28.8 1.1 1 0 0 1 1 1 0 Utp14 protein DPBB_1 PF03330.13 CEP14602.1 - 1.9e-09 37.4 0.0 4.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Peptidase_S28 PF05577.7 CEP14603.1 - 2.3e-71 240.6 0.0 3.5e-71 240.0 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CEP14603.1 - 5.8e-06 26.3 0.0 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP14603.1 - 0.044 13.3 0.1 0.044 13.3 0.1 2.3 3 1 0 3 3 3 0 alpha/beta hydrolase fold AvrPto PF11592.3 CEP14603.1 - 0.06 13.1 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Central core of the bacterial effector protein AvrPto Ribosomal_S19 PF00203.16 CEP14604.1 - 7e-33 112.0 0.5 9.4e-33 111.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 CEP14604.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH DDE_3 PF13358.1 CEP14605.1 - 2.7e-16 59.6 0.0 1.8e-09 37.5 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease zf-MIZ PF02891.15 CEP14605.1 - 0.18 11.3 2.9 0.39 10.2 0.3 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger SRP14 PF02290.10 CEP14606.1 - 2.1e-21 75.6 0.5 1.6e-19 69.6 0.3 2.5 2 0 0 2 2 2 2 Signal recognition particle 14kD protein DDE_3 PF13358.1 CEP14606.1 - 3.5e-10 39.7 0.0 1.6e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Cyclin_N PF00134.18 CEP14608.1 - 5.3e-10 38.9 1.1 9.9e-10 38.0 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CEP14608.1 - 1.6e-05 24.7 0.0 0.058 13.3 0.0 2.2 1 1 1 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 CEP14608.1 - 1.8e-05 24.4 3.3 0.00018 21.2 0.1 2.6 2 1 0 2 2 2 1 Transcription factor TFIIB repeat CBFD_NFYB_HMF PF00808.18 CEP14609.1 - 2.1e-15 56.5 0.4 3.3e-15 55.8 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEP14609.1 - 3.3e-09 36.7 0.1 5.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 APC_CDC26 PF10471.4 CEP14609.1 - 4.6 8.0 20.4 0.13 12.9 8.1 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 DEAD PF00270.24 CEP14610.1 - 8.9e-44 148.9 1.5 1.3e-43 148.3 0.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP14610.1 - 3.3e-27 94.1 0.3 3e-26 91.0 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Methyltransf_23 PF13489.1 CEP14610.1 - 2.4e-11 43.6 0.1 4.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP14610.1 - 8.2e-07 29.4 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP14610.1 - 2.1e-05 24.1 0.0 5.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP14610.1 - 0.00072 19.9 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ORC4_C PF14629.1 CEP14610.1 - 0.0054 16.1 0.7 0.062 12.6 0.1 2.8 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 4 C-terminus DUF1253 PF06862.7 CEP14610.1 - 0.025 13.0 0.0 3.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_30 PF13604.1 CEP14610.1 - 0.038 13.5 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Methyltransf_25 PF13649.1 CEP14610.1 - 0.058 13.7 0.1 0.27 11.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain AAA_19 PF13245.1 CEP14610.1 - 0.1 12.3 0.1 0.29 10.8 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Helicase_RecD PF05127.9 CEP14610.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Helicase Methyltransf_11 PF08241.7 CEP14611.1 - 4.5e-19 68.7 0.0 6.5e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP14611.1 - 2.7e-18 66.0 0.0 3.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP14611.1 - 1.6e-15 57.2 0.0 2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP14611.1 - 9.6e-15 55.1 0.0 1.5e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CEP14611.1 - 3.9e-13 48.7 0.0 5.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 CEP14611.1 - 4.4e-11 43.0 0.1 7.5e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP14611.1 - 5.3e-10 39.6 0.0 8.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP14611.1 - 6.7e-10 39.0 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP14611.1 - 7.8e-09 35.1 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CEP14611.1 - 1.6e-06 27.4 0.0 2.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 CEP14611.1 - 4.9e-05 22.5 0.0 0.00013 21.1 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 CEP14611.1 - 0.00011 21.3 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 CEP14611.1 - 0.00036 19.7 0.0 0.00058 19.0 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 CEP14611.1 - 0.00043 19.6 0.0 0.00061 19.2 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.14 CEP14611.1 - 0.0023 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 CEP14611.1 - 0.0039 16.2 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 CEP14611.1 - 0.017 13.4 0.0 0.023 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 CEP14611.1 - 0.021 14.3 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CEP14611.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.11 CEP14611.1 - 0.03 13.2 0.4 0.47 9.2 0.2 2.1 1 1 0 1 1 1 0 mRNA capping enzyme DREV PF05219.7 CEP14611.1 - 0.12 11.1 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase ADH_zinc_N PF00107.21 CEP14611.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UPF0020 PF01170.13 CEP14611.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 WW PF00397.21 CEP14612.1 - 0.0052 16.6 0.8 0.011 15.5 0.6 1.6 1 0 0 1 1 1 1 WW domain DUF605 PF04652.11 CEP14612.1 - 0.12 11.8 13.6 0.15 11.3 9.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF2076 PF09849.4 CEP14612.1 - 1.9 8.4 26.0 0.038 14.0 11.9 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3684 PF12449.3 CEP14613.1 - 3.6e-265 882.5 10.0 2.1e-260 866.7 4.0 2.8 1 1 0 2 2 2 2 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 CEP14613.1 - 3.1e-05 23.6 0.0 7.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase COX6A PF02046.10 CEP14614.1 - 2.1e-27 95.3 1.1 2.2e-27 95.2 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Arc_PepC_II PF06847.6 CEP14615.1 - 8.3 6.9 7.0 1.8 9.0 0.2 3.1 3 2 1 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II zf-MYND PF01753.13 CEP14616.1 - 3e-06 27.0 9.8 3e-06 27.0 6.8 2.7 3 0 0 3 3 3 1 MYND finger TPR_1 PF00515.23 CEP14616.1 - 0.047 13.3 0.0 1.4 8.6 0.0 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.1 CEP14616.1 - 1.4 8.1 9.2 0.068 12.3 1.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Pet127 PF08634.5 CEP14617.1 - 1.3e-105 352.4 4.0 1.3e-105 352.4 2.8 2.0 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Ribosomal_L31 PF01197.13 CEP14618.1 - 0.00029 20.7 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L31 Propep_M14 PF02244.11 CEP14619.1 - 0.027 14.1 0.1 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Carboxypeptidase activation peptide AMP-binding_C_2 PF14535.1 CEP14619.1 - 0.063 13.3 0.5 0.089 12.8 0.3 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF4006 PF13179.1 CEP14619.1 - 0.096 12.2 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Ribosomal_S22 PF08136.6 CEP14619.1 - 0.24 11.5 1.0 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 30S ribosomal protein subunit S22 family DUF1944 PF09175.5 CEP14620.1 - 0.1 12.2 0.2 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) rve PF00665.21 CEP14621.1 - 8.7e-20 71.0 0.0 2.2e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP14621.1 - 5.5e-13 48.7 0.0 2.3e-12 46.7 0.0 2.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CEP14621.1 - 4.2e-06 26.7 0.4 2.2e-05 24.4 0.3 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CEP14621.1 - 6.6e-06 26.5 0.0 2.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease UBN2 PF14223.1 CEP14621.1 - 0.0013 18.5 1.2 0.0039 16.9 0.2 2.3 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Dimerisation PF08100.6 CEP14621.1 - 0.0075 16.0 0.1 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain rve_3 PF13683.1 CEP14621.1 - 0.016 14.7 0.1 0.077 12.5 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 CEP14622.1 - 1.8e-10 40.6 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Transposase WD40 PF00400.27 CEP14626.1 - 0.0021 17.8 0.3 0.0074 16.1 0.2 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat Nbas_N PF15492.1 CEP14626.1 - 0.016 14.2 0.0 0.048 12.7 0.0 1.7 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal p53-inducible11 PF14936.1 CEP14627.1 - 0.089 12.7 0.5 0.14 12.1 0.2 1.2 1 1 0 1 1 1 0 Tumour protein p53-inducible protein 11 PMP1_2 PF08114.6 CEP14627.1 - 0.11 12.0 0.8 0.28 10.7 0.6 1.7 1 0 0 1 1 1 0 ATPase proteolipid family KOW PF00467.24 CEP14628.1 - 6.6e-11 41.4 2.4 6.6e-11 41.4 1.6 2.0 2 1 0 2 2 2 1 KOW motif DUF1442 PF07279.6 CEP14628.1 - 0.007 15.4 1.4 0.0085 15.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) zf-RING_2 PF13639.1 CEP14629.1 - 1.4e-14 53.6 7.1 2.2e-14 52.9 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP14629.1 - 6e-08 32.6 1.6 1.2e-07 31.6 1.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP14629.1 - 1.1e-06 28.2 6.1 1.8e-06 27.5 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.17 CEP14629.1 - 3.8e-06 26.5 0.0 8.9e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 CEP14629.1 - 5.2e-06 26.3 7.5 8.8e-06 25.6 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP14629.1 - 0.0034 17.0 7.6 0.0058 16.2 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP14629.1 - 0.0047 16.6 6.0 0.0071 16.0 4.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CEP14629.1 - 0.019 14.8 1.7 0.043 13.6 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4381 PF14316.1 CEP14629.1 - 0.19 11.8 0.2 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-RING_4 PF14570.1 CEP14629.1 - 5.7 6.6 9.7 10 5.8 6.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Acatn PF13000.2 CEP14630.1 - 5.5e-158 526.8 25.2 2.5e-80 270.5 10.8 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Cren7 PF11520.3 CEP14630.1 - 0.19 11.4 0.5 0.46 10.1 0.3 1.6 1 0 0 1 1 1 0 Chromatin protein Cren7 F-box-like PF12937.2 CEP14631.1 - 2.9e-05 23.6 0.0 6.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like PPR_2 PF13041.1 CEP14632.1 - 7.7e-13 48.2 0.5 4.6e-08 32.9 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 CEP14632.1 - 6.5e-08 32.2 5.6 0.033 14.4 0.0 5.6 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 CEP14632.1 - 4.3e-07 29.4 0.0 1.8 8.7 0.0 4.6 4 0 0 4 4 4 3 PPR repeat TPR_19 PF14559.1 CEP14632.1 - 0.00021 21.5 0.0 0.7 10.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP14632.1 - 0.0028 18.2 0.1 0.083 13.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_1 PF12854.2 CEP14632.1 - 0.034 13.6 7.6 13 5.3 0.1 4.3 4 0 0 4 4 4 0 PPR repeat TPR_6 PF13174.1 CEP14632.1 - 0.14 12.6 0.9 22 5.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MKT1_C PF12246.3 CEP14633.1 - 1.6e-59 200.8 1.3 1.6e-59 200.8 0.9 1.5 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CEP14633.1 - 6.8e-31 106.4 0.8 1.7e-30 105.1 0.1 2.1 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 CEP14633.1 - 1.5e-07 31.6 0.0 4.6e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CEP14633.1 - 0.0021 18.0 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region CBS PF00571.23 CEP14634.1 - 7.7e-09 35.2 0.8 0.00047 19.8 0.1 3.7 3 1 1 4 4 4 2 CBS domain tRNA_SAD PF07973.9 CEP14634.1 - 6.5e-08 32.3 0.1 1.8e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 CEP14634.1 - 0.00047 18.5 0.3 0.00098 17.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) STAT_int PF02865.12 CEP14634.1 - 0.029 14.3 1.5 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 STAT protein, protein interaction domain DHHA1 PF02272.14 CEP14634.1 - 0.099 12.3 1.3 0.25 11.0 0.9 1.7 1 0 0 1 1 1 0 DHHA1 domain XRCC4 PF06632.7 CEP14635.1 - 6.8e-06 25.1 9.4 8.4e-06 24.8 6.5 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Dicty_REP PF05086.7 CEP14635.1 - 0.019 12.7 12.0 0.026 12.2 8.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fmp27_WPPW PF10359.4 CEP14635.1 - 0.025 13.0 13.6 0.034 12.5 9.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cut8_N PF14482.1 CEP14635.1 - 0.045 13.7 1.6 0.18 11.8 1.1 2.0 1 0 0 1 1 1 0 Cut8 proteasome-binding domain BTV_NS2 PF04514.7 CEP14635.1 - 0.096 11.5 11.7 0.4 9.4 8.3 1.8 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 DUF3571 PF12095.3 CEP14635.1 - 0.21 11.8 1.9 0.41 10.9 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3571) DUF572 PF04502.8 CEP14635.1 - 0.35 10.0 16.3 0.5 9.5 11.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1840 PF08895.6 CEP14635.1 - 1.1 9.3 11.7 1 9.3 4.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) DUF2802 PF10975.3 CEP14635.1 - 1.2 8.8 4.0 7 6.4 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) IncA PF04156.9 CEP14635.1 - 1.4 8.4 7.7 2.5 7.6 5.3 1.5 1 0 0 1 1 1 0 IncA protein Sporozoite_P67 PF05642.6 CEP14635.1 - 2.7 5.7 7.8 3.4 5.4 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3246 PF11596.3 CEP14635.1 - 3.7 6.7 11.7 6.4 5.9 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SID-1_RNA_chan PF13965.1 CEP14635.1 - 4.8 5.2 8.5 6.3 4.8 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FlxA PF14282.1 CEP14635.1 - 5.3 7.0 18.2 3.3e+02 1.2 12.6 2.4 1 1 0 1 1 1 0 FlxA-like protein CHD5 PF04420.9 CEP14635.1 - 6.8 6.3 10.3 3.9 7.1 5.7 1.8 1 1 1 2 2 2 0 CHD5-like protein DUF3766 PF12611.3 CEP14636.1 - 0.25 10.9 0.7 0.62 9.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3766) Nrap PF03813.9 CEP14637.1 - 7.7e-265 881.0 0.0 9.8e-265 880.6 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Nop PF01798.13 CEP14638.1 - 5.3e-60 201.0 0.8 1.1e-59 200.0 0.6 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CEP14638.1 - 1.2e-27 95.4 0.1 2.3e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CEP14638.1 - 2.1e-22 79.0 1.0 2.1e-22 79.0 0.7 2.9 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DDHD PF02862.12 CEP14638.1 - 5.2 6.8 10.9 0.94 9.2 5.0 1.8 2 0 0 2 2 2 0 DDHD domain RVT_1 PF00078.22 CEP14639.1 - 1.8e-14 53.6 0.0 3.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PMEI PF04043.10 CEP14640.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Isochorismatase PF00857.15 CEP14642.1 - 0.00027 20.8 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 CEP14646.1 - 1.6e-08 34.6 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family DUF221 PF02714.10 CEP14647.1 - 6.3e-73 245.4 23.2 6.3e-73 245.4 16.1 2.2 2 1 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEP14647.1 - 2.2e-30 105.3 1.5 1.1e-29 102.9 1.1 2.4 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CEP14647.1 - 2.1e-10 40.9 3.9 4.2e-10 40.0 0.1 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4463) Rho_GDI PF02115.12 CEP14650.1 - 0.034 13.5 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Wbp11 PF09429.5 CEP14653.1 - 6.4e-19 67.7 14.0 6.4e-19 67.7 9.7 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 Nop14 PF04147.7 CEP14653.1 - 0.16 9.8 20.2 0.27 9.0 14.0 1.4 1 0 0 1 1 1 0 Nop14-like family FancD2 PF14631.1 CEP14653.1 - 2.6 5.0 7.1 3.5 4.5 4.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Hid1 PF12722.2 CEP14653.1 - 9.3 3.7 8.6 15 3.0 6.0 1.5 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CBM_21 PF03370.8 CEP14654.1 - 1.2e-30 105.7 1.8 3.1e-30 104.4 1.2 1.7 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CEP14654.1 - 0.24 11.4 4.2 1.9 8.6 2.9 2.3 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) Homeobox_KN PF05920.6 CEP14656.1 - 3.6e-18 64.9 0.3 9.8e-18 63.5 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CEP14656.1 - 8.4e-06 25.3 0.1 2.2e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain Spt5_N PF11942.3 CEP14656.1 - 0.029 14.9 4.3 0.029 14.9 2.9 2.8 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal IFT57 PF10498.4 CEP14656.1 - 0.13 11.0 12.2 0.052 12.2 5.3 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 PBP1_TM PF14812.1 CEP14656.1 - 0.7 10.2 16.8 0.29 11.4 3.0 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 CEP14656.1 - 0.73 10.0 7.8 6.1 7.0 0.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.6 CEP14656.1 - 4.9 4.8 12.9 0.56 7.9 4.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 CEP14656.1 - 6.5 6.2 9.3 7.5 6.0 3.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin SOBP PF15279.1 CEP14656.1 - 8 6.7 16.2 3.3 7.9 9.0 1.7 1 1 1 2 2 2 0 Sine oculis-binding protein zf-C5HC2 PF02928.11 CEP14658.1 - 0.013 15.5 1.2 4.5 7.4 0.0 2.2 2 0 0 2 2 2 0 C5HC2 zinc finger zf-UDP PF14569.1 CEP14658.1 - 0.041 13.6 0.3 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger Fer4_18 PF13746.1 CEP14658.1 - 0.094 13.1 1.3 0.16 12.3 0.9 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain TPR_12 PF13424.1 CEP14659.1 - 2e-05 24.4 2.9 0.00058 19.7 2.6 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEP14659.1 - 0.00013 21.5 4.0 0.45 10.2 0.5 3.0 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.1 CEP14659.1 - 0.0029 18.0 4.5 1.5 9.6 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP14659.1 - 0.0062 16.1 4.9 1.4 8.6 1.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP14659.1 - 0.041 14.0 7.0 1.8 8.9 0.4 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEP14659.1 - 0.062 13.2 2.5 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP14659.1 - 0.14 12.0 6.0 15 5.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Cep57_MT_bd PF06657.8 CEP14659.1 - 0.41 10.6 2.9 0.7 9.8 0.3 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TPR_19 PF14559.1 CEP14659.1 - 0.42 11.0 8.3 4.2 7.7 0.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 CEP14661.1 - 4.5e-16 58.8 18.6 5.3e-06 26.8 1.3 6.3 6 0 0 6 6 6 4 Sel1 repeat TPR_11 PF13414.1 CEP14661.1 - 0.0021 17.6 11.6 0.051 13.2 0.0 4.7 3 1 1 4 4 4 2 TPR repeat VWA_CoxE PF05762.9 CEP14661.1 - 0.022 13.8 0.4 0.054 12.6 0.0 1.7 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein TPR_2 PF07719.12 CEP14661.1 - 1.8 8.7 12.3 48 4.2 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 CEP14663.1 - 1.7e-74 250.1 0.0 1.9e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SRPRB PF09439.5 CEP14664.1 - 1.8e-41 141.3 0.0 2.2e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CEP14664.1 - 1.9e-17 63.0 0.2 3.4e-17 62.2 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP14664.1 - 0.0056 16.1 0.4 0.18 11.2 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP14664.1 - 0.0078 15.3 0.1 0.018 14.1 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 CEP14664.1 - 0.028 13.9 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Podoplanin PF05808.6 CEP14665.1 - 0.0011 18.6 0.3 0.0026 17.3 0.2 1.7 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.7 CEP14665.1 - 0.049 13.0 0.4 0.14 11.6 0.3 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor FAM70 PF14967.1 CEP14665.1 - 1.4 8.0 5.9 0.15 11.2 0.7 1.8 1 1 0 1 1 1 0 FAM70 protein Abhydrolase_1 PF00561.15 CEP14667.1 - 1.4e-09 37.8 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEP14667.1 - 2.1e-09 37.6 0.0 4.2e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP14667.1 - 7.3e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CEP14667.1 - 0.028 14.2 0.0 0.074 12.9 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 CEP14669.1 - 3e-63 213.2 0.1 3.7e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEP14669.1 - 2.4e-08 33.4 0.0 3.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 CEP14669.1 - 7.9e-06 24.8 0.0 0.02 13.6 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family DUF2424 PF10340.4 CEP14669.1 - 8.5e-06 24.6 0.0 1.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) AXE1 PF05448.7 CEP14669.1 - 0.05 12.0 0.0 0.087 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 CEP14669.1 - 0.14 11.0 0.1 0.31 9.9 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme RVT_1 PF00078.22 CEP14670.1 - 0.0016 17.8 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.13 CEP14670.1 - 0.017 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain zf-met PF12874.2 CEP14671.1 - 1.8e-12 47.0 76.5 0.014 15.6 0.5 10.4 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP14671.1 - 2.8e-07 30.4 79.5 0.01 15.9 0.4 10.6 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CEP14671.1 - 0.00014 21.9 60.7 0.0038 17.3 1.2 7.0 4 3 2 6 6 6 4 C2H2 type zinc-finger (2 copies) Ecl1 PF12855.2 CEP14671.1 - 0.035 13.3 0.3 0.035 13.3 0.2 7.1 8 0 0 8 8 8 0 Life-span regulatory factor Syncollin PF15138.1 CEP14671.1 - 0.69 9.8 6.5 0.55 10.1 0.2 2.9 3 0 0 3 3 3 0 Syncollin Ras PF00071.17 CEP14673.1 - 3e-66 221.7 0.1 4e-66 221.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP14673.1 - 3.4e-21 75.9 0.0 7.8e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP14673.1 - 7.6e-15 54.5 0.0 9.4e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP14673.1 - 3.5e-06 26.3 0.0 4.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP14673.1 - 6.3e-06 25.7 0.1 1.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CEP14673.1 - 1.5e-05 24.2 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEP14673.1 - 0.0002 21.3 0.0 0.00038 20.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP14673.1 - 0.0069 15.5 0.0 0.027 13.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEP14673.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 CEP14673.1 - 0.035 13.3 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 CEP14673.1 - 0.046 13.7 0.6 0.087 12.8 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 CEP14673.1 - 0.075 12.7 0.1 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CEP14673.1 - 0.08 13.0 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF3321 PF11968.3 CEP14676.1 - 0.041 13.4 0.2 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase (DUF3321) F-box PF00646.28 CEP14679.1 - 0.0011 18.6 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain DUF2897 PF11446.3 CEP14679.1 - 0.099 12.4 2.5 0.53 10.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) F-box-like PF12937.2 CEP14679.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 F-box-like Coatomer_WDAD PF04053.9 CEP14680.1 - 6.4e-139 463.5 0.0 1.2e-138 462.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CEP14680.1 - 3.2e-113 378.4 0.2 4e-113 378.1 0.1 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CEP14680.1 - 5.9e-53 174.9 9.8 1.1e-10 41.0 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CEP14680.1 - 0.00046 18.4 4.1 0.84 7.6 0.0 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 SGL PF08450.7 CEP14680.1 - 0.0035 16.7 0.0 0.19 11.0 0.0 3.1 3 0 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Clathrin PF00637.15 CEP14680.1 - 0.014 14.9 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS HypA PF01155.14 CEP14680.1 - 0.021 14.4 1.4 1.2 8.8 0.6 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Apc4_WD40 PF12894.2 CEP14680.1 - 0.057 12.9 0.1 38 3.8 0.0 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.15 CEP14682.1 - 2.3e-274 910.9 8.7 2.7e-274 910.7 6.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP14682.1 - 1.8e-15 56.3 0.1 1.6e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CEP14682.1 - 0.0055 15.8 0.7 0.029 13.4 0.0 2.3 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CEP14682.1 - 0.0097 15.5 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 CEP14682.1 - 0.042 12.7 0.0 0.085 11.7 0.0 1.5 1 0 0 1 1 1 0 StbA protein plasmid_Toxin PF12703.2 CEP14682.1 - 0.098 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system Pro_isomerase PF00160.16 CEP14683.1 - 3.7e-37 127.9 0.1 4.7e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_hydro_20 PF00728.17 CEP14685.1 - 3.5e-28 98.7 0.1 6.2e-28 97.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain ATG16 PF08614.6 CEP14687.1 - 0.0022 17.8 0.1 0.0022 17.8 0.1 4.0 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CEP14687.1 - 0.036 13.2 7.0 1.1 8.3 0.0 2.9 1 1 2 4 4 4 0 Reovirus sigma C capsid protein DUF2203 PF09969.4 CEP14687.1 - 0.14 12.3 0.3 0.14 12.3 0.2 4.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF2730 PF10805.3 CEP14687.1 - 1.8 8.3 12.0 3.3 7.4 0.2 5.0 3 1 3 6 6 6 0 Protein of unknown function (DUF2730) Microtub_assoc PF07989.6 CEP14687.1 - 2 8.2 14.9 0.12 12.2 1.2 4.4 5 0 0 5 5 5 0 Microtubule associated Snapin_Pallidin PF14712.1 CEP14687.1 - 5.6 7.3 19.3 0.085 13.1 0.6 4.1 4 1 0 4 4 4 0 Snapin/Pallidin IncA PF04156.9 CEP14687.1 - 5.9 6.4 32.6 2.6 7.5 2.3 4.3 1 1 2 3 3 3 0 IncA protein NBP1 PF08537.5 CEP14687.1 - 6.2 5.9 16.6 3.9 6.5 8.0 2.1 1 1 0 2 2 2 0 Fungal Nap binding protein NBP1 Mit_KHE1 PF10173.4 CEP14688.1 - 9.1e-42 143.0 6.2 1.5e-41 142.2 4.3 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Pkinase PF00069.20 CEP14689.1 - 2.9e-74 249.4 0.1 2.9e-74 249.4 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14689.1 - 9.5e-44 149.3 0.0 2.1e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14689.1 - 7.6e-07 28.3 0.0 1.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP14689.1 - 0.001 18.8 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CEP14689.1 - 0.0065 15.5 0.4 0.012 14.6 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Toxin_42 PF15522.1 CEP14689.1 - 0.081 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 42 DUF3759 PF12585.3 CEP14690.1 - 0.46 10.4 6.1 0.93 9.4 2.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3759) RNase_T PF00929.19 CEP14692.1 - 1e-24 87.6 0.1 3.6e-24 85.8 0.0 2.1 2 0 0 2 2 2 1 Exonuclease zf-C3HC4 PF00097.20 CEP14692.1 - 0.00025 20.6 13.3 0.00025 20.6 9.2 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEP14692.1 - 0.00054 19.7 13.3 0.00054 19.7 9.2 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DNA_pol_A_exo1 PF01612.15 CEP14692.1 - 0.002 17.6 0.0 0.021 14.2 0.0 2.6 1 1 0 1 1 1 1 3'-5' exonuclease zf-RING_2 PF13639.1 CEP14692.1 - 0.052 13.3 25.2 0.084 12.7 15.6 2.7 2 1 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.1 CEP14692.1 - 0.071 12.8 10.0 0.28 10.9 6.9 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CEP14692.1 - 0.26 10.9 18.6 0.48 10.1 8.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP14692.1 - 0.51 10.4 21.4 0.017 15.1 8.8 3.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CEP14692.1 - 4.7 7.0 13.7 0.23 11.2 5.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Pkinase PF00069.20 CEP14693.1 - 1.3e-63 214.5 0.0 2.5e-62 210.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14693.1 - 1.2e-28 99.8 0.1 2.6e-22 79.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEP14693.1 - 3.8e-05 22.7 0.3 0.00067 18.7 0.0 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CEP14693.1 - 9.1e-05 22.2 0.1 0.097 12.3 0.2 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEP14693.1 - 0.00029 19.9 0.1 0.001 18.1 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 CEP14693.1 - 0.00063 20.2 0.7 0.0015 18.9 0.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 CEP14693.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 CEP14693.1 - 0.014 14.2 0.2 0.025 13.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Med15 PF09606.5 CEP14693.1 - 6.1 4.9 24.3 7.6 4.5 16.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HD PF01966.17 CEP14695.1 - 3.5e-09 36.7 0.3 5.7e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 HD domain FHA PF00498.21 CEP14696.1 - 4.1e-16 58.8 0.2 1.1e-15 57.5 0.1 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CEP14696.1 - 3e-09 36.5 8.4 6e-09 35.5 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP14696.1 - 5.7e-06 26.3 4.4 1.5e-05 24.9 3.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP14696.1 - 0.00012 21.7 7.4 0.00023 20.7 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP14696.1 - 0.00078 19.1 6.8 0.0015 18.1 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CEP14696.1 - 0.0014 18.6 9.4 0.003 17.5 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CEP14696.1 - 0.026 14.1 3.9 0.055 13.1 2.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 CEP14696.1 - 0.044 13.6 0.9 0.087 12.6 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3277 PF11681.3 CEP14698.1 - 0.022 14.2 1.2 0.035 13.5 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3277) DUF2939 PF11159.3 CEP14698.1 - 0.36 11.0 3.0 51 4.1 0.1 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2939) YpjP PF14005.1 CEP14698.1 - 0.44 10.3 7.3 1.2 8.9 0.6 2.7 1 1 1 2 2 2 0 YpjP-like protein Upf2 PF04050.9 CEP14699.1 - 2.4 7.8 9.5 4 7.1 6.6 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF3439 PF11921.3 CEP14700.1 - 0.087 12.5 6.5 0.06 13.1 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Pex14_N PF04695.8 CEP14700.1 - 0.36 10.8 6.5 0.11 12.5 0.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NUDE_C PF04880.8 CEP14700.1 - 0.87 9.9 6.3 0.12 12.7 1.1 2.0 2 1 0 2 2 2 0 NUDE protein, C-terminal conserved region ASXH PF13919.1 CEP14701.1 - 1e-19 70.7 2.6 1e-19 70.7 1.8 2.3 2 0 0 2 2 2 1 Asx homology domain PsaN PF05479.6 CEP14702.1 - 0.017 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) EphA2_TM PF14575.1 CEP14703.1 - 0.0099 16.2 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.9 CEP14703.1 - 0.012 15.3 0.2 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2681 PF10883.3 CEP14703.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Herpes_gE PF02480.11 CEP14703.1 - 0.042 12.1 0.0 0.06 11.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.1 CEP14703.1 - 0.064 12.9 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 TMEM154 PF15102.1 CEP14703.1 - 0.11 12.2 0.6 0.25 11.0 0.4 1.6 1 1 0 1 1 1 0 TMEM154 protein family Pho88 PF10032.4 CEP14703.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) DUF1191 PF06697.7 CEP14703.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Kelch_4 PF13418.1 CEP14704.1 - 8.2e-07 28.7 0.1 4.3 7.1 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP14704.1 - 3.2e-05 23.8 0.9 6.8 7.0 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 CEP14704.1 - 0.0024 17.3 4.9 4.6 6.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 CEP14704.1 - 0.0041 17.0 0.0 2 8.4 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 CEP14704.1 - 0.015 15.0 0.0 28 4.7 0.0 4.1 4 0 0 4 4 4 0 Kelch motif EphA2_TM PF14575.1 CEP14704.1 - 0.043 14.2 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 CEP14704.1 - 0.08 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.1 CEP14704.1 - 0.16 12.0 0.1 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CoatB PF10389.4 CEP14704.1 - 0.26 11.1 3.8 0.48 10.3 2.6 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B AJAP1_PANP_C PF15298.1 CEP14705.1 - 0.006 16.4 0.4 0.023 14.5 0.0 1.9 1 1 1 2 2 2 1 AJAP1/PANP C-terminus DUF2681 PF10883.3 CEP14705.1 - 0.027 14.6 0.3 0.047 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3007 PF11460.3 CEP14705.1 - 0.04 13.9 0.0 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) DUF719 PF05334.8 CEP14705.1 - 0.052 13.5 0.0 0.052 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) TMEM51 PF15345.1 CEP14705.1 - 0.061 13.0 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 MFS_2 PF13347.1 CEP14705.1 - 0.067 11.5 0.0 0.094 11.0 0.0 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein MLANA PF14991.1 CEP14705.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A VSP PF03302.8 CEP14705.1 - 0.26 9.8 0.5 0.39 9.2 0.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Kelch_4 PF13418.1 CEP14706.1 - 2.6e-08 33.4 4.0 0.043 13.5 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP14706.1 - 0.00012 22.1 0.0 0.15 12.2 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP14706.1 - 0.0021 18.1 7.1 2 8.6 0.0 5.5 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.20 CEP14706.1 - 0.039 13.5 3.9 7.9 6.1 0.0 4.1 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 CEP14706.1 - 0.086 12.8 3.1 5.3 7.1 0.1 3.3 4 0 0 4 4 4 0 Kelch motif Protoglobin PF11563.3 CEP14708.1 - 2.3e-43 147.6 0.0 2.8e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protoglobin adh_short PF00106.20 CEP14709.1 - 6.4e-36 123.7 0.2 9.7e-36 123.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP14709.1 - 3.1e-25 89.3 0.2 5.4e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP14709.1 - 2.3e-18 66.4 0.2 3.8e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CEP14709.1 - 5.9e-09 35.6 0.3 1.2e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CEP14709.1 - 6.4e-07 28.5 0.2 9e-07 28.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CEP14709.1 - 0.032 14.0 0.1 0.073 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 CEP14709.1 - 0.061 12.9 0.1 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.8 CEP14709.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Dimer_Tnp_hAT PF05699.9 CEP14710.1 - 0.012 15.1 0.0 0.086 12.4 0.0 2.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Sulfatase PF00884.18 CEP14712.1 - 4.4e-61 206.7 2.1 7.7e-61 205.9 1.4 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CEP14712.1 - 0.0039 16.5 0.1 0.019 14.3 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 CEP14712.1 - 0.004 15.6 0.3 0.66 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF229) DUF3820 PF12843.2 CEP14712.1 - 0.026 14.1 0.2 0.067 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) Iso_dh PF00180.15 CEP14713.1 - 6.7e-77 258.7 0.0 8.2e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sel1 PF08238.7 CEP14714.1 - 7.8e-103 334.6 87.2 2.2e-06 28.0 0.4 30.3 30 2 0 30 30 29 20 Sel1 repeat TPR_11 PF13414.1 CEP14714.1 - 1.5e-11 43.7 57.5 0.0033 17.0 2.9 14.8 15 2 2 17 17 17 5 TPR repeat TPR_7 PF13176.1 CEP14714.1 - 1e-07 31.2 21.5 0.0015 18.2 0.1 9.1 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.12 CEP14714.1 - 1.9e-06 27.3 61.9 0.025 14.4 0.5 16.2 18 1 0 18 18 17 4 Tetratricopeptide repeat TPR_8 PF13181.1 CEP14714.1 - 3.8e-06 26.3 36.5 0.00089 18.8 0.4 12.8 15 0 0 15 15 14 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP14714.1 - 1.4e-05 25.2 25.8 4 8.3 0.0 13.0 14 1 1 15 15 14 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP14714.1 - 0.00012 21.9 50.7 0.37 10.7 3.0 13.4 13 2 2 15 15 15 4 Tetratricopeptide repeat TPR_6 PF13174.1 CEP14714.1 - 0.0002 21.6 46.6 0.39 11.2 0.4 15.6 15 3 0 15 15 14 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP14714.1 - 0.00031 20.7 29.3 9.5 6.7 0.0 13.1 16 0 0 16 16 14 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEP14714.1 - 0.0018 17.7 58.4 0.012 15.1 0.4 14.8 17 0 0 17 17 17 4 Tetratricopeptide repeat TPR_19 PF14559.1 CEP14714.1 - 0.0043 17.3 22.5 0.49 10.7 0.2 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP14714.1 - 0.012 16.2 54.3 14 6.5 0.0 15.4 15 2 3 18 18 18 0 Tetratricopeptide repeat WWE PF02825.15 CEP14715.1 - 0.0001 21.6 0.0 0.0021 17.4 0.0 2.4 2 0 0 2 2 2 1 WWE domain FKS1_dom1 PF14288.1 CEP14715.1 - 0.064 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3568 PF12092.3 CEP14715.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) G-patch PF01585.18 CEP14726.1 - 3e-09 36.5 1.7 6.2e-09 35.5 1.2 1.6 1 0 0 1 1 1 1 G-patch domain zf-met PF12874.2 CEP14726.1 - 4.7e-06 26.6 1.3 9.5e-06 25.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP14726.1 - 5e-06 26.4 6.7 8.1e-06 25.8 4.1 1.8 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 CEP14726.1 - 0.0069 16.0 4.8 0.012 15.2 3.3 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_6 PF13912.1 CEP14726.1 - 0.012 15.4 1.9 0.023 14.6 1.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CEP14726.1 - 0.015 15.6 1.6 0.031 14.6 1.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CEP14726.1 - 0.027 14.5 8.3 0.042 13.9 5.7 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) G-patch_2 PF12656.2 CEP14726.1 - 0.03 14.1 0.2 0.03 14.1 0.1 2.4 3 0 0 3 3 3 0 DExH-box splicing factor binding site DUF4407 PF14362.1 CEP14726.1 - 2.3 7.1 13.1 3 6.7 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Evr1_Alr PF04777.8 CEP14726.1 - 3.6 7.5 7.7 7.7 6.4 5.3 1.6 1 1 0 1 1 1 0 Erv1 / Alr family PP-binding PF00550.20 CEP14727.1 - 8.3e-13 48.4 0.4 1.1e-12 48.0 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CEP14727.1 - 6e-06 26.1 0.4 7.5e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 Acyl-carrier Arf PF00025.16 CEP14728.1 - 2.3e-32 111.6 0.2 1.2e-27 96.2 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 CEP14728.1 - 2.7e-12 46.3 0.0 9.1e-12 44.6 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CEP14728.1 - 4.1e-10 40.1 0.0 8.1e-08 32.7 0.0 2.0 1 1 1 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 CEP14728.1 - 5.7e-09 35.4 0.0 4.3e-07 29.3 0.0 2.0 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CEP14728.1 - 7.5e-08 31.4 0.7 1.2e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CEP14728.1 - 7e-07 28.6 0.1 0.0016 17.6 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEP14728.1 - 3e-06 27.1 0.8 0.0012 18.8 0.6 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP14728.1 - 0.00014 21.3 0.0 0.001 18.5 0.0 1.8 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 CEP14728.1 - 0.0029 17.0 0.3 0.71 9.2 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CEP14728.1 - 0.0057 16.4 0.1 0.96 9.2 0.1 2.1 1 1 1 2 2 2 1 Dynamin family MobB PF03205.9 CEP14728.1 - 0.026 14.2 0.1 0.035 13.8 0.1 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 CEP14728.1 - 0.031 13.5 1.7 0.074 12.3 0.3 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 CEP14728.1 - 0.046 13.3 0.5 2.8 7.5 0.0 2.3 1 1 1 2 2 2 0 NACHT domain NYD-SP28_assoc PF14775.1 CEP14728.1 - 0.064 12.9 0.3 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain GCR1_C PF12550.3 CEP14729.1 - 4.8e-12 45.5 0.2 3.7e-11 42.7 0.1 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes zf-CCHC_4 PF14392.1 CEP14730.1 - 1.9e-05 24.1 9.7 0.0023 17.5 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 CEP14730.1 - 0.12 12.3 18.8 0.26 11.2 4.9 2.4 2 0 0 2 2 2 0 Zinc knuckle Ank_2 PF12796.2 CEP14731.1 - 8.1e-17 61.3 2.9 1.3e-12 47.8 0.2 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEP14731.1 - 3.5e-13 48.6 3.7 1e-08 34.5 0.3 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CEP14731.1 - 1.2e-12 47.9 2.9 2.4e-10 40.6 0.2 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP14731.1 - 5e-10 38.6 3.9 5.7e-06 26.0 0.2 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 CEP14731.1 - 2.6e-08 33.8 2.2 1.1e-05 25.5 0.2 4.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.8 CEP14731.1 - 0.0016 18.0 0.5 0.013 15.1 0.0 2.6 2 1 0 2 2 2 1 KilA-N domain Filament PF00038.16 CEP14731.1 - 0.014 14.8 18.9 0.35 10.2 4.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein SlyX PF04102.7 CEP14731.1 - 1.7 9.0 10.1 4.2 7.8 0.1 3.6 3 0 0 3 3 3 0 SlyX Mnd1 PF03962.10 CEP14731.1 - 1.9 8.1 20.3 0.1 12.2 2.9 2.9 2 1 1 3 3 3 0 Mnd1 family ADIP PF11559.3 CEP14731.1 - 2.1 8.2 18.9 3.1 7.7 2.3 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DAO PF01266.19 CEP14732.1 - 3.6e-53 180.7 0.0 4.3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP14732.1 - 4.1e-05 23.5 0.2 0.00014 21.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CEP14732.1 - 0.0071 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CEP14732.1 - 0.031 14.3 0.1 0.73 9.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP14732.1 - 0.057 12.3 0.1 0.098 11.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 CEP14732.1 - 0.06 12.1 0.5 0.11 11.3 0.1 1.7 2 1 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 CEP14732.1 - 0.065 13.0 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEP14732.1 - 0.089 12.6 4.8 0.79 9.5 3.4 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEP14732.1 - 0.11 11.5 0.1 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain EMP24_GP25L PF01105.19 CEP14733.1 - 2.1e-43 148.1 0.2 3.9e-43 147.2 0.1 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Hydrolase_6 PF13344.1 CEP14733.1 - 9.1e-30 102.5 0.0 5.5e-29 100.0 0.0 2.3 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP14733.1 - 4.7e-16 58.2 0.0 1.2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CEP14733.1 - 1.8e-13 51.4 0.0 3.7e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP14733.1 - 1e-09 38.8 0.0 0.0015 18.7 0.0 2.7 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.1 CEP14733.1 - 4e-09 36.4 0.1 1.2e-08 34.9 0.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CEP14733.1 - 3.8e-05 22.6 0.2 0.0008 18.5 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CEP14733.1 - 5.6e-05 22.6 0.2 0.00029 20.3 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CEP14733.1 - 7e-05 22.3 0.5 0.00071 19.2 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain UPF0154 PF03672.8 CEP14733.1 - 0.0033 17.0 0.0 0.66 9.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF2608 PF11019.3 CEP14733.1 - 0.017 14.1 0.0 0.94 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) RNA_pol_Rpb4 PF03874.11 CEP14733.1 - 0.24 11.3 2.5 0.37 10.7 0.1 2.6 3 0 0 3 3 2 0 RNA polymerase Rpb4 RRM_1 PF00076.17 CEP14734.1 - 6.5e-23 80.1 0.0 1.7e-10 40.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 CEP14734.1 - 9.1e-22 75.2 2.1 1.2e-05 24.4 0.0 7.2 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat RRM_6 PF14259.1 CEP14734.1 - 2.9e-12 46.3 0.1 1.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP14734.1 - 2.9e-11 43.0 0.8 1.7e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OmpH PF03938.9 CEP14734.1 - 0.00035 20.5 14.1 0.00035 20.5 9.8 2.4 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) Cnd1 PF12717.2 CEP14734.1 - 0.00041 20.2 0.5 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 SR-25 PF10500.4 CEP14734.1 - 0.0029 17.1 6.7 0.0064 15.9 2.5 2.6 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein FimP PF09766.4 CEP14734.1 - 0.019 14.0 16.5 0.037 13.0 11.4 1.4 1 0 0 1 1 1 0 Fms-interacting protein RR_TM4-6 PF06459.7 CEP14734.1 - 0.051 13.4 7.4 0.1 12.4 5.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.8 CEP14734.1 - 0.93 9.3 25.2 1.1 9.1 14.3 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4557 PF15101.1 CEP14734.1 - 2.2 8.1 20.1 6.3 6.5 14.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3464 PF11947.3 CEP14734.1 - 2.3 7.6 6.2 6.6 6.1 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF912 PF06024.7 CEP14734.1 - 2.4 8.2 6.2 6.4 6.8 4.3 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MRP-S31 PF15433.1 CEP14734.1 - 2.7 7.3 18.1 0.24 10.7 9.1 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Pinin_SDK_memA PF04696.8 CEP14735.1 - 2e-22 79.1 20.6 2e-22 79.1 14.3 2.1 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF104 PF01954.11 CEP14735.1 - 7 6.7 8.6 1.2 9.1 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF104 Myosin_head PF00063.16 CEP14736.1 - 1.2e-249 829.9 5.6 1.2e-249 829.9 3.9 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.22 CEP14736.1 - 1.5e-18 64.5 26.2 8.3e-06 24.9 0.4 6.1 5 0 0 5 5 5 5 IQ calmodulin-binding motif AAA_22 PF13401.1 CEP14736.1 - 0.0015 18.6 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CEP14736.1 - 0.04 13.6 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CEP14736.1 - 0.06 13.3 1.7 0.33 10.9 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 CEP14736.1 - 0.064 13.4 1.1 1.2 9.3 0.0 3.3 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.22 CEP14736.1 - 0.076 13.3 2.2 0.32 11.3 0.0 3.0 2 0 0 2 2 2 0 ABC transporter WW PF00397.21 CEP14737.1 - 4.1e-12 45.7 5.0 1.1e-11 44.2 3.4 1.8 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 CEP14737.1 - 2.1 8.3 34.1 67 3.4 23.4 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Seryl_tRNA_N PF02403.17 CEP14738.1 - 0.98 9.4 7.7 0.9 9.5 2.7 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CytochromB561_N PF09786.4 CEP14738.1 - 1.7 7.0 14.7 2.6 6.3 10.2 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal TSC21 PF15217.1 CEP14740.1 - 0.072 12.7 0.2 0.08 12.6 0.1 1.0 1 0 0 1 1 1 0 TSC21 family NAP PF00956.13 CEP14740.1 - 0.073 12.1 0.8 0.083 12.0 0.6 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) APC_crr PF05923.7 CEP14740.1 - 1.2 8.8 7.1 2.7 7.7 4.9 1.6 1 0 0 1 1 1 0 APC cysteine-rich region PBP1_TM PF14812.1 CEP14740.1 - 1.3 9.3 3.7 2.4 8.4 1.7 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1378 PF07125.6 CEP14741.1 - 0.054 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) zf-C2H2_jaz PF12171.3 CEP14742.1 - 2.3e-05 24.3 18.7 0.0013 18.7 1.2 19.3 20 0 0 20 20 20 8 Zinc-finger double-stranded RNA-binding DUF466 PF04328.8 CEP14742.1 - 3.3e-05 23.6 19.8 0.38 10.6 0.4 6.5 6 0 0 6 6 6 3 Protein of unknown function (DUF466) zf-met PF12874.2 CEP14742.1 - 0.0012 18.9 0.9 0.0012 18.9 0.6 18.6 19 0 0 19 19 19 5 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CEP14742.1 - 0.01 16.1 3.2 0.01 16.1 2.2 20.7 22 0 0 22 22 22 0 Zinc finger, C2H2 type DUF2946 PF11162.3 CEP14742.1 - 0.27 11.4 9.1 0.16 12.1 0.3 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2946) MFS_1 PF07690.11 CEP14743.1 - 4.1e-22 78.3 34.1 4.1e-21 75.0 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP14743.1 - 6.1e-06 24.8 6.6 6.1e-06 24.8 4.6 3.2 1 1 3 4 4 4 2 MFS/sugar transport protein Sugar_tr PF00083.19 CEP14743.1 - 3.5e-05 22.5 30.8 0.0011 17.6 3.6 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter B-block_TFIIIC PF04182.7 CEP14744.1 - 2e-11 43.5 0.1 3.7e-08 33.0 0.0 3.0 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC CotH PF08757.6 CEP14745.1 - 3.2e-41 141.6 3.3 4.8e-41 141.0 2.3 1.2 1 0 0 1 1 1 1 CotH protein Med10 PF09748.4 CEP14746.1 - 4.8e-29 100.7 0.2 5.9e-29 100.4 0.2 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex VCBS PF13517.1 CEP14747.1 - 4.5e-05 23.7 0.0 0.015 15.6 0.0 3.4 3 1 1 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.1 CEP14747.1 - 0.001 18.7 0.1 1.4 8.7 0.0 3.7 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 CEP14747.1 - 0.0069 16.0 0.1 0.46 10.2 0.0 2.6 2 0 0 2 2 2 1 FG-GAP repeat BBS2_C PF14782.1 CEP14747.1 - 0.019 13.5 0.1 0.032 12.8 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PI3_PI4_kinase PF00454.22 CEP14748.1 - 5.4e-44 150.4 0.1 1e-43 149.5 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PLDc_N PF13396.1 CEP14749.1 - 0.24 11.1 3.7 0.65 9.7 0.2 2.4 1 1 2 3 3 3 0 Phospholipase_D-nuclease N-terminal p450 PF00067.17 CEP14750.1 - 1.6e-67 228.0 0.0 2.1e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Adeno_terminal PF02459.10 CEP14750.1 - 0.12 10.5 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein AhpC-TSA PF00578.16 CEP14751.1 - 5.1e-40 136.0 0.0 1.6e-39 134.4 0.0 1.9 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEP14751.1 - 1.2e-14 54.1 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CEP14751.1 - 3.8e-12 45.6 0.1 8.7e-12 44.4 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LRR_4 PF12799.2 CEP14751.1 - 9.3e-09 34.7 24.5 1e-05 25.0 0.2 6.3 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CEP14751.1 - 1.2e-05 24.8 26.0 0.57 10.4 0.0 8.3 8 1 1 9 9 9 3 Leucine Rich repeat LRR_8 PF13855.1 CEP14751.1 - 0.029 14.1 24.0 0.024 14.3 2.1 5.6 3 1 2 5 5 5 0 Leucine rich repeat TPR_12 PF13424.1 CEP14751.1 - 0.11 12.3 8.4 0.061 13.2 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_1 PF00560.28 CEP14751.1 - 0.7 10.1 17.4 1.1 9.5 0.2 7.0 8 0 0 8 8 8 0 Leucine Rich Repeat TPR_8 PF13181.1 CEP14751.1 - 0.95 9.4 7.5 6.7 6.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_7 PF13504.1 CEP14751.1 - 4.9 7.7 16.9 2.7 8.5 0.1 7.2 8 0 0 8 8 8 0 Leucine rich repeat Dynactin_p22 PF07426.6 CEP14752.1 - 9.6e-11 41.2 2.1 1.1e-10 41.0 1.5 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 GAS PF13851.1 CEP14752.1 - 0.0026 16.9 5.7 0.088 11.9 2.1 2.3 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Retrotrans_gag PF03732.12 CEP14752.1 - 0.0058 16.6 1.7 3.1 7.9 0.1 2.5 3 0 0 3 3 2 2 Retrotransposon gag protein Zwint PF15556.1 CEP14752.1 - 0.01 15.1 0.7 0.018 14.3 0.5 1.4 1 0 0 1 1 1 0 ZW10 interactor Scaffolding_pro PF11418.3 CEP14752.1 - 0.013 15.8 0.5 0.089 13.1 0.0 2.3 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF2205 PF10224.4 CEP14752.1 - 0.017 14.6 2.2 0.018 14.6 0.3 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) LOH1CR12 PF10158.4 CEP14752.1 - 0.019 14.7 3.5 0.24 11.2 0.7 2.4 2 1 0 2 2 2 0 Tumour suppressor protein UBN2 PF14223.1 CEP14752.1 - 0.022 14.5 3.8 0.56 10.0 0.8 2.6 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type BAG PF02179.11 CEP14752.1 - 0.036 14.1 1.0 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 BAG domain FliD_C PF07195.7 CEP14752.1 - 0.039 13.2 7.0 0.58 9.4 0.2 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Wx5_PLAF3D7 PF09688.5 CEP14752.1 - 0.042 13.8 4.7 0.9 9.4 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (Wx5_PLAF3D7) BCDHK_Adom3 PF10436.4 CEP14752.1 - 0.042 13.3 1.0 0.14 11.6 0.7 1.9 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Fzo_mitofusin PF04799.8 CEP14752.1 - 0.056 12.8 4.8 0.056 12.8 0.6 2.2 2 1 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.7 CEP14752.1 - 0.063 13.0 6.9 0.16 11.8 0.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 CEP14752.1 - 0.082 13.1 5.7 10 6.4 4.0 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Dad2 PF08654.5 CEP14752.1 - 0.083 12.8 1.3 1.8 8.5 0.0 2.6 3 0 0 3 3 2 0 DASH complex subunit Dad2 Rabaptin PF03528.10 CEP14752.1 - 0.083 12.8 4.4 0.3 11.0 1.4 2.5 2 1 1 3 3 3 0 Rabaptin Hemocyanin_N PF03722.9 CEP14752.1 - 0.095 12.8 1.3 0.34 11.0 0.2 2.0 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain Nsp1_C PF05064.8 CEP14752.1 - 0.098 12.2 3.4 1.2 8.7 0.3 2.8 3 0 0 3 3 3 0 Nsp1-like C-terminal region MitMem_reg PF13012.1 CEP14752.1 - 0.17 11.9 4.1 0.14 12.2 0.8 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Vac_Fusion PF02346.11 CEP14752.1 - 0.19 11.1 1.1 1.2 8.5 0.1 2.6 2 1 0 2 2 2 0 Chordopoxvirus fusion protein Reo_sigmaC PF04582.7 CEP14752.1 - 0.22 10.6 1.3 11 5.0 0.0 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 CEP14752.1 - 0.28 11.3 6.6 6.3 6.9 0.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 CEP14752.1 - 0.31 10.9 7.4 1.3 8.9 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 CEP14752.1 - 0.61 9.6 3.0 8 6.0 2.1 2.1 1 1 1 2 2 2 0 IncA protein DUF16 PF01519.11 CEP14752.1 - 0.69 10.1 5.0 3.6 7.8 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.5 CEP14752.1 - 0.69 10.0 6.1 4.5 7.3 1.8 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 CEP14752.1 - 0.69 9.6 5.2 1.5 8.6 0.3 2.8 3 0 0 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.2 CEP14752.1 - 0.73 9.6 6.5 0.33 10.8 0.8 2.4 1 1 1 2 2 2 0 Tropomyosin like Med10 PF09748.4 CEP14752.1 - 0.9 9.3 4.0 10 5.9 2.7 2.3 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Kinetocho_Slk19 PF12709.2 CEP14752.1 - 1.4 9.0 5.8 7.5 6.6 1.0 2.9 1 1 2 3 3 3 0 Central kinetochore-associated Syntaxin-6_N PF09177.6 CEP14752.1 - 2 8.8 4.8 7.5 7.0 0.3 2.9 1 1 1 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.10 CEP14752.1 - 4.6 6.8 6.7 1.5 8.3 0.3 2.7 2 1 1 3 3 3 0 Septum formation initiator PI3_PI4_kinase PF00454.22 CEP14753.1 - 4e-44 150.8 0.1 1.5e-43 148.9 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CEP14753.1 - 5.8e-11 41.9 8.1 5.8e-11 41.9 5.6 2.7 2 1 0 2 2 2 1 FAT domain FATC PF02260.15 CEP14753.1 - 6.9e-08 31.7 0.2 2.6e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 FATC domain TPR_8 PF13181.1 CEP14753.1 - 0.0019 17.8 1.6 0.2 11.4 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP14753.1 - 0.016 15.7 0.1 38 5.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP14753.1 - 0.022 14.6 0.7 11 6.2 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RVT_1 PF00078.22 CEP14754.1 - 1.9e-15 56.7 0.0 7.5e-15 54.8 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CEP14754.1 - 6.2e-05 22.7 3.8 6.2e-05 22.7 2.6 2.7 3 0 0 3 3 3 1 Zinc knuckle Asp_protease_2 PF13650.1 CEP14754.1 - 0.00019 21.8 0.7 0.0023 18.4 0.0 2.8 2 1 1 3 3 3 1 Aspartyl protease RVP_2 PF08284.6 CEP14754.1 - 0.0015 18.5 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP14754.1 - 0.0073 16.1 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DENN PF02141.16 CEP14755.1 - 2.7e-23 82.6 0.1 2.8e-13 49.9 0.0 2.6 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.13 CEP14755.1 - 2.5e-15 56.1 1.7 7.8e-15 54.5 1.2 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 CEP14755.1 - 1.2e-14 54.0 0.9 2.9e-14 52.8 0.6 1.7 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.17 CEP14755.1 - 0.41 10.4 6.8 0.91 9.3 4.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Allantoicase PF03561.10 CEP14756.1 - 3.1e-48 163.1 0.0 6.1e-23 80.9 0.0 2.3 2 0 0 2 2 2 2 Allantoicase repeat F-box-like PF12937.2 CEP14757.1 - 0.0034 17.0 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP14757.1 - 0.071 12.7 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 F-box domain zf-C2H2 PF00096.21 CEP14758.1 - 1.8e-06 27.9 8.2 0.00085 19.5 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP14758.1 - 3e-05 24.0 8.9 0.0099 16.1 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP14758.1 - 0.001 19.2 2.8 0.001 19.2 1.9 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEP14758.1 - 0.02 14.7 0.9 0.02 14.7 0.6 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CEP14758.1 - 0.056 13.1 0.6 0.15 11.7 0.4 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-met PF12874.2 CEP14758.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3128 PF11326.3 CEP14759.1 - 7.7e-22 77.2 4.3 7.7e-22 77.2 3.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3128) LSM PF01423.17 CEP14759.1 - 2.4e-16 59.0 1.7 3.9e-16 58.3 1.2 1.3 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 CEP14759.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Ndufs5 PF10200.4 CEP14759.1 - 0.14 12.1 1.5 0.25 11.3 1.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.7 CEP14759.1 - 0.22 11.4 4.7 1.1 9.1 3.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Tmemb_14 PF03647.8 CEP14760.1 - 1.3e-26 92.8 4.0 1.6e-26 92.5 2.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 CEP14760.1 - 0.075 13.2 0.8 0.13 12.4 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) DoxX_2 PF13564.1 CEP14760.1 - 0.35 10.8 2.9 0.48 10.4 2.0 1.3 1 0 0 1 1 1 0 DoxX-like family Gly-zipper_OmpA PF13436.1 CEP14760.1 - 5.9 6.5 7.7 8.2 6.1 4.8 1.5 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain CybS PF05328.7 CEP14761.1 - 2.3e-36 124.3 0.0 3.2e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 CybS DTW PF03942.10 CEP14762.1 - 3.1e-31 108.1 0.0 4.9e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 DTW domain DUF3672 PF12421.3 CEP14762.1 - 0.075 13.1 0.1 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Fibronectin type III protein Glyco_hydro_20 PF00728.17 CEP14763.1 - 1.3e-88 297.5 0.8 2e-88 296.8 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CEP14763.1 - 1.1e-22 81.0 0.1 3.8e-22 79.3 0.1 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CEP14763.1 - 2.5e-07 31.2 0.2 4.2e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GST_N_3 PF13417.1 CEP14764.1 - 9.6e-13 48.1 0.0 1.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEP14764.1 - 2.2e-08 33.9 0.1 4.4e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEP14764.1 - 9.2e-08 31.8 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CEP14764.1 - 3.4e-06 26.9 0.0 5.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP14764.1 - 6.1e-06 26.3 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CEP14764.1 - 8.6e-05 22.9 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GATA PF00320.22 CEP14765.1 - 1.2e-16 59.7 4.4 2e-16 59.0 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger CDC45 PF02724.9 CEP14765.1 - 0.01 13.9 7.2 0.013 13.6 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3027 PF11228.3 CEP14765.1 - 0.021 14.5 1.9 0.47 10.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) DZR PF12773.2 CEP14765.1 - 0.17 11.7 1.6 3.2 7.6 0.9 2.1 1 1 1 2 2 2 0 Double zinc ribbon NOA36 PF06524.7 CEP14765.1 - 0.64 9.2 12.9 1.4 8.0 8.9 1.6 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 CEP14765.1 - 1.3 6.8 23.6 2.1 6.1 16.4 1.2 1 0 0 1 1 1 0 Nop14-like family zf-ribbon_3 PF13248.1 CEP14765.1 - 6.4 6.1 6.0 19 4.6 4.2 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF4098 PF13345.1 CEP14766.1 - 2.7e-17 62.5 36.2 2.1e-07 30.7 1.1 6.5 4 2 3 7 7 7 5 Domain of unknown function (DUF4098) FYRC PF05965.9 CEP14767.1 - 8e-18 64.0 0.0 1.9e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 CEP14767.1 - 8.3e-18 63.5 0.5 1.7e-17 62.5 0.1 1.8 2 0 0 2 2 2 1 F/Y-rich N-terminus O-FucT PF10250.4 CEP14768.1 - 2.4e-15 56.5 0.3 4.1e-05 22.8 0.0 4.0 3 1 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase RLAN PF14401.1 CEP14768.1 - 0.011 15.3 0.0 0.03 13.8 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain LON PF02190.11 CEP14769.1 - 1.9e-14 53.8 0.0 1.7e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 CEP14769.1 - 2.2e-10 40.4 10.1 4.8e-10 39.3 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP14769.1 - 1.3e-09 37.7 9.1 3e-09 36.5 6.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP14769.1 - 1.2e-08 34.4 7.1 2.5e-08 33.4 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP14769.1 - 1.3e-08 34.3 10.0 2.7e-08 33.3 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP14769.1 - 3e-08 33.2 9.2 5.5e-08 32.4 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEP14769.1 - 8.3e-08 31.9 9.8 1.7e-07 30.9 6.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP14769.1 - 0.00049 19.7 7.3 0.0012 18.5 5.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 CEP14769.1 - 0.00062 19.2 6.3 0.0014 18.1 4.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CEP14769.1 - 0.016 14.7 5.8 0.016 14.7 4.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CEP14769.1 - 0.029 14.1 3.6 0.057 13.2 2.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 CEP14769.1 - 0.14 12.0 3.1 0.54 10.1 2.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CEP14769.1 - 0.33 11.1 6.3 1.3 9.2 4.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger DUF410 PF04190.8 CEP14770.1 - 3e-53 181.0 0.5 3.6e-53 180.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Ank_2 PF12796.2 CEP14771.1 - 2.3e-24 85.5 4.8 5e-11 42.7 0.0 3.5 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP14771.1 - 3.6e-21 75.1 3.7 2.8e-09 37.2 0.0 5.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CEP14771.1 - 1.1e-17 62.8 8.5 2.8e-06 26.8 0.1 5.6 5 2 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 CEP14771.1 - 1.9e-15 55.3 4.5 1.4e-05 24.8 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 CEP14771.1 - 1.1e-14 54.1 2.7 4.5e-06 26.7 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) DNA_mis_repair PF01119.14 CEP14772.1 - 1.9e-16 59.6 0.8 4.7e-16 58.3 0.5 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CEP14772.1 - 5.7e-12 45.4 1.4 2.1e-11 43.6 1.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CEP14772.1 - 3e-09 36.5 0.5 7.7e-09 35.2 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-RVT PF13966.1 CEP14773.1 - 0.0063 16.7 3.1 0.013 15.8 0.5 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase p450 PF00067.17 CEP14774.1 - 7.7e-80 268.6 0.0 9.4e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_FANCE PF11510.3 CEP14774.1 - 0.2 10.7 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE Mito_carr PF00153.22 CEP14775.1 - 5.5e-84 276.0 0.1 2.9e-29 100.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex24p PF06398.6 CEP14776.1 - 8.3e-38 130.0 10.5 1.4e-37 129.3 7.3 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4112 PF13430.1 CEP14776.1 - 1.9e-24 85.6 1.6 2.1e-24 85.4 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4112) Aminotran_3 PF00202.16 CEP14778.1 - 3e-104 348.5 0.0 3.8e-104 348.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CEP14778.1 - 0.016 14.1 0.0 0.072 12.0 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II PPTA PF01239.17 CEP14779.1 - 7.6e-46 151.6 20.9 3.8e-10 38.6 0.2 6.5 6 0 0 6 6 6 6 Protein prenyltransferase alpha subunit repeat CN_hydrolase PF00795.17 CEP14779.1 - 4.4e-28 97.9 0.0 7.9e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.17 CEP14780.1 - 8.5e-09 34.9 0.0 1.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP14780.1 - 8.6e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP14780.1 - 6.6e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AstE_AspA PF04952.9 CEP14780.1 - 0.024 13.5 0.6 6.6 5.5 0.0 2.6 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family RRP7 PF12923.2 CEP14780.1 - 8.7 6.3 16.1 3.2 7.7 8.8 2.1 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) DUF4536 PF15055.1 CEP14781.1 - 0.22 11.6 1.4 0.41 10.7 1.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) DUF1328 PF07043.8 CEP14781.1 - 7 6.7 6.0 1.2 9.1 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) Peptidase_A22B PF04258.8 CEP14782.1 - 9.5e-28 97.4 14.1 4.7e-17 62.3 0.7 2.1 1 1 1 2 2 2 2 Signal peptide peptidase Apolipoprotein PF01442.13 CEP14782.1 - 0.031 13.7 0.7 0.049 13.1 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain RPA_C PF08784.6 CEP14783.1 - 4.1e-06 27.1 0.1 9.9e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 CEP14783.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TBPIP PF07106.8 CEP14783.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Carboxyl_trans PF01039.17 CEP14784.1 - 4.9e-189 628.7 0.0 5.8e-189 628.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CEP14784.1 - 0.00045 19.4 0.7 0.001 18.3 0.0 1.8 2 1 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) DUF4243 PF14027.1 CEP14785.1 - 1.4e-28 100.3 0.0 1.7e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pkinase PF00069.20 CEP14786.1 - 1.2e-52 178.6 0.0 1.7e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14786.1 - 3.2e-37 128.0 0.0 4.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14786.1 - 2.1e-05 23.6 0.0 3.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CEP14786.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Orbi_VP5 PF00901.12 CEP14787.1 - 0.0008 17.7 3.7 0.00087 17.6 2.6 1.0 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP5 RRP7 PF12923.2 CEP14787.1 - 0.0041 17.1 1.1 0.0054 16.7 0.7 1.4 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) Baculo_PEP_C PF04513.7 CEP14787.1 - 0.0044 16.8 3.6 0.0044 16.8 2.5 1.7 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 CEP14787.1 - 0.012 14.9 2.0 0.85 9.0 0.2 3.0 2 1 1 3 3 3 0 Chordopoxvirus fusion protein Gtr1_RagA PF04670.7 CEP14787.1 - 0.038 13.1 0.8 0.048 12.8 0.5 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4168 PF13767.1 CEP14787.1 - 0.11 13.1 7.1 0.085 13.4 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) Cep57_MT_bd PF06657.8 CEP14787.1 - 0.11 12.3 3.3 2.3 8.2 0.2 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Nup54 PF13874.1 CEP14787.1 - 0.12 11.9 1.7 0.17 11.5 1.2 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Laminin_II PF06009.7 CEP14787.1 - 0.15 11.8 3.1 4.8 6.9 0.1 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 CEP14787.1 - 0.16 11.7 2.3 0.4 10.4 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Chordopox_A30L PF06015.7 CEP14787.1 - 0.17 11.4 9.8 0.2 11.3 0.5 2.4 2 1 0 2 2 2 0 Chordopoxvirus A30L protein DUF972 PF06156.8 CEP14787.1 - 0.17 12.2 5.0 0.33 11.3 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Phage_Mu_Gam PF07352.7 CEP14787.1 - 0.21 11.0 5.6 0.14 11.6 2.3 1.7 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein KapB PF08810.5 CEP14787.1 - 0.35 10.9 2.5 0.95 9.5 0.2 2.2 1 1 1 2 2 2 0 Kinase associated protein B IncA PF04156.9 CEP14787.1 - 0.85 9.1 7.7 0.72 9.4 3.0 1.9 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 CEP14787.1 - 1 9.1 6.7 6.5 6.6 3.2 2.3 2 1 0 2 2 2 0 Tropomyosin like GrpE PF01025.14 CEP14787.1 - 1.8 8.1 6.9 18 4.8 4.8 2.1 1 1 0 1 1 1 0 GrpE DUF240 PF03086.9 CEP14787.1 - 2.5 7.7 8.8 0.3 10.7 1.7 2.1 2 1 0 2 2 2 0 MG032/MG096/MG288 family 2 Fib_alpha PF08702.5 CEP14787.1 - 8.1 6.5 7.6 13 5.8 5.2 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NUDIX PF00293.23 CEP14788.1 - 1.7e-09 37.4 0.0 1.7e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain L27_1 PF09058.5 CEP14788.1 - 0.021 14.7 0.0 16 5.4 0.0 3.0 2 1 1 3 3 3 0 L27_1 DNA_pol3_a_NI PF14480.1 CEP14789.1 - 0.063 12.9 1.0 0.17 11.5 0.7 1.8 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I zf-C2H2 PF00096.21 CEP14790.1 - 2.7e-08 33.6 8.6 7.5e-05 22.8 1.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP14790.1 - 2.8e-07 30.5 0.9 2.8e-07 30.5 0.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP14790.1 - 4.8e-07 29.6 6.1 0.00054 20.0 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP14790.1 - 0.015 15.1 2.7 0.35 10.8 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3134 PF11332.3 CEP14790.1 - 0.21 11.7 0.2 0.21 11.7 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3134) C2-set PF05790.10 CEP14790.1 - 1.1 9.2 7.6 2 8.4 0.3 3.1 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Cnd1 PF12717.2 CEP14791.1 - 3.6e-59 199.5 10.7 1.5e-58 197.5 2.3 3.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CEP14791.1 - 9.1e-38 129.5 0.1 9.1e-38 129.5 0.1 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 CEP14791.1 - 2.7e-12 46.7 1.7 2.4e-05 24.5 0.0 5.4 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 CEP14791.1 - 2.6e-07 30.1 0.8 0.43 10.7 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat Adaptin_N PF01602.15 CEP14791.1 - 1.7e-05 23.3 13.2 9.2e-05 20.9 0.3 4.3 3 1 0 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.1 CEP14791.1 - 0.0026 18.1 1.6 1.2 9.7 0.0 5.1 5 1 1 6 6 6 1 HEAT-like repeat zf-C2H2_2 PF12756.2 CEP14792.1 - 1e-32 112.2 13.7 3.4e-27 94.4 0.6 3.4 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CEP14792.1 - 9.4e-10 38.3 16.7 3.9e-07 30.0 2.7 4.2 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP14792.1 - 3.4e-07 30.2 3.1 3.4e-07 30.2 2.1 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CEP14792.1 - 0.0042 17.3 11.4 1.6 9.1 0.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger AKAP95 PF04988.7 CEP14792.1 - 0.0049 16.6 6.2 0.28 10.9 0.1 2.8 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 CEP14792.1 - 0.067 13.5 18.3 1 9.8 0.8 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type BIR PF00653.16 CEP14792.1 - 0.48 10.8 5.8 2.3 8.6 0.1 3.7 4 0 0 4 4 4 0 Inhibitor of Apoptosis domain zf-C2H2_6 PF13912.1 CEP14792.1 - 0.7 9.8 6.8 6.7 6.7 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Papo_T_antigen PF02380.10 CEP14792.1 - 1.5 8.7 6.7 1.6 8.7 0.1 3.2 4 0 0 4 4 4 0 T-antigen specific domain HECT PF00632.20 CEP14794.1 - 1.1e-86 290.8 0.3 2.3e-86 289.8 0.1 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Mito_carr PF00153.22 CEP14794.1 - 3.4e-67 222.1 2.3 6.4e-23 80.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C58 PF03543.9 CEP14794.1 - 0.11 12.0 0.6 0.24 10.8 0.4 1.6 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen PFK PF00365.15 CEP14795.1 - 8e-173 572.9 10.4 1.9e-119 397.7 2.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 CEP14795.1 - 2.1e-05 25.1 0.0 0.00014 22.4 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase-like domain DUF4646 PF15496.1 CEP14795.1 - 0.065 13.2 0.0 0.27 11.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) DDE_3 PF13358.1 CEP14798.1 - 0.00032 20.4 0.0 0.00085 19.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 CEP14799.1 - 1.6e-21 76.6 0.1 2.5e-21 75.9 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP14799.1 - 0.0046 16.1 0.0 0.0057 15.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease YdjO PF14169.1 CEP14799.1 - 0.033 13.6 0.1 0.072 12.5 0.1 1.6 1 1 0 1 1 1 0 Cold-inducible protein YdjO DDE_Tnp_ISAZ013 PF07592.6 CEP14799.1 - 0.068 11.9 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain ResIII PF04851.10 CEP14800.1 - 3.6e-20 72.5 0.0 1.4e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CEP14800.1 - 7.4e-14 51.2 0.0 1.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 CEP14800.1 - 3.7e-08 33.0 0.0 6.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP14800.1 - 7.3e-07 28.9 0.0 1.7e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 CEP14800.1 - 0.00028 19.7 0.0 0.00044 19.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF2461 PF09365.5 CEP14801.1 - 6.9e-58 195.5 0.1 6.9e-58 195.5 0.1 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) Daxx PF03344.10 CEP14801.1 - 0.032 12.7 19.9 0.035 12.6 13.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF2478 PF10649.4 CEP14801.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Seipin PF06775.9 CEP14802.1 - 4.8e-48 163.3 4.1 7.8e-48 162.6 2.8 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FAD_binding_3 PF01494.14 CEP14802.1 - 3.2e-19 69.1 0.0 1e-09 37.9 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 CEP14802.1 - 4e-07 29.2 0.0 0.00021 20.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 CEP14802.1 - 0.0003 19.7 0.0 0.00063 18.6 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 CEP14802.1 - 0.00031 19.7 0.0 0.02 13.8 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CEP14802.1 - 0.0021 18.0 0.0 0.0075 16.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP14802.1 - 0.0035 17.1 0.0 0.0095 15.7 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 CEP14802.1 - 0.0084 14.7 0.1 0.02 13.5 0.1 1.6 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 CEP14802.1 - 0.012 15.9 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP14802.1 - 0.062 13.3 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEP14802.1 - 0.084 11.7 0.2 0.13 11.1 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CEP14802.1 - 0.19 10.1 0.2 0.38 9.1 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein IMS PF00817.15 CEP14803.1 - 7.4e-47 158.8 0.2 3.6e-46 156.6 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 CEP14803.1 - 3.8e-17 62.4 0.1 1e-16 61.0 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CEP14803.1 - 2.3e-05 24.1 0.0 9.2e-05 22.2 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif SKI PF01202.17 CEP14804.1 - 3.7e-08 33.3 0.0 5.5e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 CEP14804.1 - 6.9e-06 26.3 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP14804.1 - 2.8e-05 24.9 0.0 3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP14804.1 - 0.00018 21.3 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP14804.1 - 0.00064 19.4 0.1 0.0024 17.6 0.1 1.9 1 1 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CEP14804.1 - 0.0075 16.4 0.0 0.065 13.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CEP14804.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CPT PF07931.7 CEP14804.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA PF00004.24 CEP14804.1 - 0.025 14.8 0.1 0.039 14.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA_lig_kinase PF08303.6 CEP14804.1 - 0.041 13.7 0.1 0.097 12.5 0.0 1.6 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF3265 PF11665.3 CEP14804.1 - 0.05 13.4 0.5 0.088 12.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) AAA_16 PF13191.1 CEP14804.1 - 0.065 13.2 0.1 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Herpes_Helicase PF02689.9 CEP14804.1 - 0.11 10.2 0.1 0.14 9.8 0.1 1.1 1 0 0 1 1 1 0 Helicase PRK PF00485.13 CEP14804.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DSPc PF00782.15 CEP14805.1 - 2.5e-26 91.8 0.0 5.6e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 CEP14805.1 - 7.9e-07 29.4 0.1 0.00067 19.9 0.0 2.9 2 1 0 2 2 2 2 Rhodanese-like domain Y_phosphatase2 PF03162.8 CEP14805.1 - 0.00022 20.6 0.0 0.00043 19.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CEP14805.1 - 0.0045 16.3 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CEP14805.1 - 0.01 16.0 0.0 0.035 14.3 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family Med23 PF11573.3 CEP14805.1 - 0.03 11.7 0.0 0.044 11.1 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 TFIID-18kDa PF02269.11 CEP14806.1 - 0.0047 16.7 0.2 0.0073 16.0 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Spc7 PF08317.6 CEP14806.1 - 0.043 12.4 4.2 0.054 12.1 2.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AIP3 PF03915.8 CEP14806.1 - 0.11 11.3 5.5 0.13 11.1 3.8 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Sec20 PF03908.8 CEP14806.1 - 0.13 11.9 3.6 0.18 11.5 1.1 2.0 1 1 1 2 2 2 0 Sec20 Med9 PF07544.8 CEP14806.1 - 0.77 9.5 5.0 5 6.9 0.6 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MBD_C PF14048.1 CEP14806.1 - 4.4 7.9 9.8 0.25 11.9 2.1 2.0 1 1 1 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Adeno_PIX PF03955.9 CEP14806.1 - 10 6.7 10.5 3.3 8.2 3.2 2.2 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Retrotrans_gag PF03732.12 CEP14807.1 - 1.2e-06 28.4 1.0 1.8e-06 27.9 0.7 1.4 1 1 0 1 1 1 1 Retrotransposon gag protein UvrD_C_2 PF13538.1 CEP14809.1 - 0.0017 18.5 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 CEP14809.1 - 0.024 13.6 0.2 0.032 13.1 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase MFS_1 PF07690.11 CEP14810.1 - 2.6e-49 167.8 15.3 2.6e-49 167.8 10.6 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP14810.1 - 7.6e-13 47.8 8.7 7.6e-13 47.8 6.0 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CEP14810.1 - 1.3e-08 33.5 5.9 2.1e-08 32.8 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 CEP14810.1 - 5.2e-07 28.6 2.9 0.0005 18.8 0.2 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF791) OATP PF03137.15 CEP14810.1 - 5e-05 21.5 5.2 0.0019 16.3 1.5 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 CEP14810.1 - 0.00016 20.3 12.1 0.00016 20.3 8.4 2.2 3 0 0 3 3 3 1 Vacuole effluxer Atg22 like MFS_3 PF05977.8 CEP14810.1 - 0.00062 18.0 1.5 0.0012 17.1 1.0 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.2 CEP14810.1 - 0.0012 18.5 0.1 0.075 12.8 0.1 3.7 4 1 1 5 5 5 1 MFS_1 like family HLH PF00010.21 CEP14811.1 - 1.9e-11 43.4 0.3 4.6e-11 42.2 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nucleoplasmin PF03066.10 CEP14811.1 - 0.79 9.2 11.3 1.1 8.7 7.0 1.8 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 CEP14811.1 - 1.6 7.8 10.2 2.5 7.3 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein zf-C2H2 PF00096.21 CEP14812.1 - 3.7e-12 45.8 14.2 5.8e-06 26.3 2.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP14812.1 - 6.3e-08 32.4 17.3 0.00033 20.7 1.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP14812.1 - 5.7e-07 29.5 20.9 9.4e-07 28.8 2.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-BED PF02892.10 CEP14812.1 - 0.025 14.3 5.3 0.17 11.6 0.4 2.6 2 0 0 2 2 2 0 BED zinc finger zf-TRAF PF02176.13 CEP14812.1 - 0.54 10.6 4.9 2.2 8.7 0.1 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met PF12874.2 CEP14812.1 - 2.2 8.5 15.2 2.8 8.2 1.2 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP14812.1 - 2.7 8.2 11.0 2.8 8.2 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CEP14812.1 - 8.2 6.6 9.0 0.41 10.7 0.4 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) LMBR1 PF04791.11 CEP14813.1 - 1.1e-12 47.2 13.8 6.9e-12 44.6 1.3 2.1 2 0 0 2 2 2 2 LMBR1-like membrane protein DUF2040 PF09745.4 CEP14813.1 - 0.042 13.6 2.3 0.066 13.0 1.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) DUF4131 PF13567.1 CEP14813.1 - 1.3 8.4 17.8 0.08 12.3 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Mit_ribos_Mrp51 PF11709.3 CEP14814.1 - 2.1e-13 50.1 10.1 3.1e-10 39.7 7.0 3.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF4634 PF15465.1 CEP14814.1 - 0.042 14.0 0.8 0.067 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) DUF3759 PF12585.3 CEP14815.1 - 2.4e-10 40.1 9.3 5.1e-10 39.1 6.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Ricin_B_lectin PF00652.17 CEP14815.1 - 6e-06 26.3 0.1 0.2 11.6 0.0 2.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP14815.1 - 7.8e-06 26.2 0.1 0.071 13.4 0.0 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like MULE PF10551.4 CEP14817.1 - 3.1e-06 27.2 0.0 6.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CEP14817.1 - 0.1 11.1 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Sugar_tr PF00083.19 CEP14820.1 - 2.3e-51 174.7 22.2 2.8e-51 174.5 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP14820.1 - 6.8e-26 90.8 33.0 4.9e-24 84.7 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldolase_II PF00596.16 CEP14821.1 - 4.3e-44 150.3 0.0 5.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Bromo_TP PF07524.8 CEP14822.1 - 2.6e-15 55.8 0.0 4.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.24 CEP14822.1 - 6e-09 35.4 2.1 1.2e-08 34.4 1.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEP14822.1 - 0.00026 20.2 0.2 0.00049 19.3 0.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 CEP14822.1 - 0.039 14.1 0.5 0.039 14.1 0.3 4.8 6 0 0 6 6 6 0 PHD domain of transcriptional enhancer, Asx Thioredoxin PF00085.15 CEP14823.1 - 1e-31 108.7 0.6 9.7e-27 92.6 0.2 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CEP14823.1 - 1.5e-21 77.0 0.2 2.7e-17 63.1 0.0 2.6 1 1 0 2 2 2 2 Thioredoxin-like domain Calsequestrin PF01216.12 CEP14823.1 - 1.3e-09 37.2 0.2 3.7e-09 35.8 0.1 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.1 CEP14823.1 - 6.9e-09 35.7 1.4 0.00011 22.2 0.1 4.2 4 1 1 5 5 5 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CEP14823.1 - 1.2e-07 31.9 0.3 5e-05 23.4 0.1 3.8 4 1 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CEP14823.1 - 5.8e-05 23.0 0.7 0.0015 18.5 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 CEP14823.1 - 0.00055 19.6 0.3 0.29 10.8 0.1 2.9 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_3 PF13192.1 CEP14823.1 - 0.0012 18.5 0.0 0.0075 16.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain DUF2847 PF11009.3 CEP14823.1 - 0.067 12.7 0.0 6 6.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Thioredoxin_9 PF14595.1 CEP14823.1 - 1 8.9 3.5 0.72 9.4 0.0 2.5 4 0 0 4 4 4 0 Thioredoxin 6PGD PF00393.14 CEP14824.1 - 3.6e-134 446.5 0.0 4.6e-134 446.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CEP14824.1 - 2.4e-54 183.5 0.0 3.6e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CEP14824.1 - 0.0091 16.0 0.0 0.083 12.9 0.0 2.4 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CEP14824.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NuiA PF07924.6 CEP14825.1 - 0.00015 21.6 0.3 0.00023 21.1 0.2 1.2 1 0 0 1 1 1 1 Nuclease A inhibitor-like protein Pyr_redox_3 PF13738.1 CEP14826.1 - 2.4e-24 86.5 0.0 9.3e-24 84.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEP14826.1 - 8.1e-18 63.9 2.0 1.3e-16 59.9 1.4 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CEP14826.1 - 9.3e-11 41.2 3.0 2.3e-09 36.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEP14826.1 - 1.1e-09 38.1 0.0 3.6e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP14826.1 - 3e-06 27.2 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP14826.1 - 0.00029 20.6 2.5 0.11 12.3 0.0 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.12 CEP14826.1 - 0.00081 18.5 0.3 0.029 13.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 CEP14826.1 - 0.0052 15.7 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CEP14826.1 - 0.032 14.6 1.6 3 8.3 0.2 3.6 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CEP14826.1 - 0.12 11.2 1.8 3.1 6.5 0.1 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CEP14826.1 - 0.18 10.6 0.1 0.28 9.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain CUE PF02845.11 CEP14827.1 - 1.3e-06 27.7 0.0 2.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain DER1 PF04511.10 CEP14827.1 - 8.7e-06 25.3 5.1 1.3e-05 24.7 3.5 1.2 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 CEP14827.1 - 1.8e-05 24.7 6.5 3.2e-05 23.9 4.5 1.3 1 0 0 1 1 1 1 Rhomboid family UBA PF00627.26 CEP14827.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF1751 PF08551.5 CEP14827.1 - 2.4 8.5 6.0 0.36 11.1 0.1 2.4 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) RNA_pol_Rpb4 PF03874.11 CEP14828.1 - 7e-24 84.0 2.8 8.6e-24 83.8 1.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 SET_assoc PF11767.3 CEP14831.1 - 0.059 12.6 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-C2H2_jaz PF12171.3 CEP14833.1 - 0.12 12.4 0.3 0.12 12.4 0.2 2.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding LIM PF00412.17 CEP14833.1 - 0.62 10.1 3.4 22 5.2 0.1 2.5 2 0 0 2 2 2 0 LIM domain Cwf_Cwc_15 PF04889.7 CEP14834.1 - 9.1e-71 238.4 26.8 1.1e-70 238.1 18.6 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 CEP14834.1 - 0.0054 16.2 10.8 0.0078 15.7 7.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Osteopontin PF00865.13 CEP14834.1 - 0.023 13.9 19.8 0.039 13.2 13.7 1.4 1 0 0 1 1 1 0 Osteopontin Nop53 PF07767.6 CEP14834.1 - 0.025 13.5 24.3 0.035 13.1 16.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Daxx PF03344.10 CEP14834.1 - 0.17 10.3 24.6 0.18 10.2 17.0 1.1 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 CEP14834.1 - 0.88 9.3 8.8 1.3 8.7 6.1 1.4 1 0 0 1 1 1 0 DDHD domain Ebola_NP PF05505.7 CEP14834.1 - 1.4 6.8 13.5 1.6 6.6 9.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein CDC27 PF09507.5 CEP14834.1 - 1.8 7.6 21.1 2.2 7.4 14.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Bd3614_N PF14442.1 CEP14834.1 - 1.8 8.5 9.7 3.2 7.7 6.7 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Astro_capsid PF03115.9 CEP14834.1 - 2.2 6.4 12.3 2.6 6.1 8.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 CEP14834.1 - 7.2 4.3 34.7 8.5 4.1 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 CEP14834.1 - 8.5 6.1 22.1 12 5.6 15.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COX16 PF14138.1 CEP14834.1 - 9.9 6.4 12.4 0.69 10.1 0.7 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Aminotran_1_2 PF00155.16 CEP14835.1 - 9e-62 209.1 0.0 1.1e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CEP14835.1 - 0.0012 17.2 0.0 0.004 15.4 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CEP14835.1 - 0.0085 14.8 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.8 CEP14835.1 - 0.14 10.7 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Allinase p450 PF00067.17 CEP14836.1 - 1.3e-72 244.8 0.0 1.6e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FliT PF05400.8 CEP14838.1 - 0.15 12.4 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Flagellar protein FliT rve PF00665.21 CEP14839.1 - 8.1e-11 42.0 0.0 1.8e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 CEP14839.1 - 0.068 12.6 0.4 0.22 11.0 0.1 2.0 2 0 0 2 2 2 0 Integrase Zinc binding domain Hydant_A_N PF05378.8 CEP14841.1 - 0.0019 17.7 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Astro_capsid PF03115.9 CEP14842.1 - 1.8 6.7 4.1 2.6 6.1 2.9 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Transposase_21 PF02992.9 CEP14844.1 - 0.0053 15.8 0.5 0.11 11.5 0.0 2.3 2 0 0 2 2 2 1 Transposase family tnp2 zf-C2H2_4 PF13894.1 CEP14844.1 - 0.0098 16.1 1.4 0.0098 16.1 0.9 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP14844.1 - 0.082 13.0 1.1 0.082 13.0 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C3HC PF07967.8 CEP14844.1 - 0.087 12.5 1.5 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like Rpr2 PF04032.11 CEP14845.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1691 PF07950.6 CEP14845.1 - 0.13 12.1 0.0 10 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Viral_Beta_CD PF04530.7 CEP14846.1 - 0.029 14.5 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family CAP_GLY PF01302.20 CEP14847.1 - 6e-25 86.7 0.5 9.1e-25 86.1 0.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain Kinesin PF00225.18 CEP14848.1 - 5.1e-110 367.3 0.3 5.1e-110 367.3 0.2 2.6 3 1 0 3 3 3 1 Kinesin motor domain WD40 PF00400.27 CEP14849.1 - 8.4e-26 88.8 3.1 4.1e-10 39.1 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat VID27 PF08553.5 CEP14849.1 - 0.015 13.5 6.0 0.019 13.2 4.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Rep_fac-A_C PF08646.5 CEP14849.1 - 0.042 13.5 4.4 0.12 12.1 3.1 1.7 1 0 0 1 1 1 0 Replication factor-A C terminal domain Nop14 PF04147.7 CEP14849.1 - 0.086 10.7 17.9 0.12 10.2 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family KTSC PF13619.1 CEP14849.1 - 0.1 12.2 0.2 0.3 10.7 0.1 1.9 2 0 0 2 2 2 0 KTSC domain CDC45 PF02724.9 CEP14849.1 - 0.4 8.6 9.8 0.74 7.7 6.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Cytochrome-c551 PF10643.4 CEP14849.1 - 2.1 7.5 4.7 0.71 9.1 0.3 2.3 2 1 1 3 3 3 0 Photosystem P840 reaction-centre cytochrome c-551 RNA_pol_Rpc4 PF05132.9 CEP14849.1 - 2.4 8.1 5.6 18 5.3 4.4 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 PHD PF00628.24 CEP14849.1 - 5.2 6.8 14.7 0.69 9.6 2.0 3.0 3 0 0 3 3 3 0 PHD-finger SDA1 PF05285.7 CEP14849.1 - 5.9 6.0 18.6 10 5.3 12.9 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 CEP14849.1 - 6.6 5.0 22.3 10 4.4 15.5 1.2 1 0 0 1 1 1 0 Daxx Family zf-C3HC4_2 PF13923.1 CEP14849.1 - 9.3 6.3 10.9 0.31 11.1 2.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HEAT_2 PF13646.1 CEP14850.1 - 4.9e-49 164.5 11.5 1.6e-15 57.1 0.1 4.7 2 1 5 7 7 7 6 HEAT repeats HEAT_PBS PF03130.11 CEP14850.1 - 8.5e-27 90.8 0.2 0.00015 21.9 0.0 7.0 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.17 CEP14850.1 - 3.7e-11 42.1 1.4 0.25 11.5 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 CEP14850.1 - 2.7e-09 37.2 5.1 0.0095 16.4 0.0 6.0 3 2 4 7 7 7 3 HEAT-like repeat GIT_SHD PF08518.6 CEP14850.1 - 2.8e-09 36.1 0.6 6.4e-09 35.0 0.4 1.6 1 0 0 1 1 1 1 Spa2 homology domain (SHD) of GIT APG6 PF04111.7 CEP14850.1 - 0.00035 19.7 22.5 0.00079 18.5 15.6 1.5 1 0 0 1 1 1 1 Autophagy protein Apg6 Arm PF00514.18 CEP14850.1 - 0.034 13.9 0.2 0.8 9.6 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 CEP14850.1 - 0.094 12.7 0.8 1.1 9.2 0.0 3.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion IncA PF04156.9 CEP14850.1 - 0.31 10.6 14.8 0.91 9.0 10.3 1.9 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CEP14850.1 - 2.1 6.1 15.0 3.3 5.4 10.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCPsignal PF00015.16 CEP14850.1 - 2.4 7.6 12.6 0.63 9.5 5.8 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 CEP14850.1 - 3.6 7.7 24.6 0.13 12.4 6.7 3.9 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LMBR1 PF04791.11 CEP14850.1 - 6.4 5.2 6.7 11 4.5 4.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PROCN PF08083.6 CEP14852.1 - 4.5e-222 736.8 4.9 7.4e-222 736.0 3.4 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CEP14852.1 - 7.1e-128 424.7 0.3 1.2e-127 423.9 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CEP14852.1 - 1.3e-89 297.6 2.3 2.9e-89 296.5 1.6 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CEP14852.1 - 7.7e-83 275.6 3.9 2e-82 274.2 2.7 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CEP14852.1 - 3.1e-69 230.8 0.1 6.1e-69 229.8 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 CEP14852.1 - 1.2e-44 150.9 0.0 3e-44 149.7 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 CEP14852.1 - 2.5e-42 142.6 0.1 6.2e-42 141.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 CEP14852.1 - 9.4e-08 31.7 0.0 2.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Matrilin_ccoil PF10393.4 CEP14853.1 - 0.033 13.5 0.1 0.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin MRP PF09387.5 CEP14855.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Tropomyosin_1 PF12718.2 CEP14857.1 - 1.3e-28 99.6 48.0 2e-20 73.1 20.3 2.5 1 1 2 3 3 3 2 Tropomyosin like Tropomyosin PF00261.15 CEP14857.1 - 2.7e-08 33.1 42.4 0.00035 19.7 14.8 2.3 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 CEP14857.1 - 1.8e-06 27.2 44.3 4e-06 26.1 21.9 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 CEP14857.1 - 2.8e-05 24.0 48.1 0.013 15.3 19.6 2.8 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 CEP14857.1 - 3.3e-05 23.7 40.0 0.0089 15.9 2.0 5.2 3 1 2 5 5 5 3 bZIP transcription factor APG6 PF04111.7 CEP14857.1 - 0.00012 21.2 47.6 0.042 12.9 16.6 2.1 1 1 1 2 2 2 2 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 CEP14857.1 - 0.001 18.9 48.8 0.048 13.5 17.4 3.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.1 CEP14857.1 - 0.0014 18.0 45.9 0.0024 17.3 31.7 1.8 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Myosin_tail_1 PF01576.14 CEP14857.1 - 0.0015 16.4 44.7 0.0051 14.6 10.5 2.0 1 1 1 2 2 2 2 Myosin tail SlyX PF04102.7 CEP14857.1 - 0.0026 18.0 4.3 0.0026 18.0 3.0 4.9 2 1 2 4 4 3 2 SlyX IncA PF04156.9 CEP14857.1 - 0.0033 17.0 52.7 0.1 12.1 21.0 2.7 1 1 1 2 2 2 2 IncA protein ADIP PF11559.3 CEP14857.1 - 0.0047 16.8 48.7 1.2 8.9 4.1 3.3 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 CEP14857.1 - 0.0092 15.9 40.9 0.061 13.2 13.2 2.5 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein bZIP_2 PF07716.10 CEP14857.1 - 0.0097 15.7 45.7 0.88 9.4 2.9 5.5 2 1 2 5 5 5 2 Basic region leucine zipper TMF_DNA_bd PF12329.3 CEP14857.1 - 0.015 15.0 54.5 0.036 13.8 4.5 4.5 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.3 CEP14857.1 - 0.036 11.4 43.8 0.041 11.2 30.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DivIC PF04977.10 CEP14857.1 - 0.067 12.6 53.2 0.26 10.8 3.6 5.1 2 1 3 5 5 5 0 Septum formation initiator Filament PF00038.16 CEP14857.1 - 0.069 12.6 42.4 0.28 10.5 18.2 2.3 1 1 1 2 2 2 0 Intermediate filament protein SCO1-SenC PF02630.9 CEP14857.1 - 0.07 12.7 6.3 0.25 10.9 0.1 2.3 1 1 1 2 2 2 0 SCO1/SenC Laminin_II PF06009.7 CEP14857.1 - 0.22 11.2 30.9 0.36 10.5 8.9 2.7 1 1 0 2 2 2 0 Laminin Domain II AAA_13 PF13166.1 CEP14857.1 - 0.25 9.7 41.4 0.48 8.8 28.7 1.5 1 1 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 CEP14857.1 - 0.27 11.4 39.6 0.8 9.8 5.5 4.6 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.16 CEP14857.1 - 0.46 9.9 23.4 0.078 12.5 4.6 2.8 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3450 PF11932.3 CEP14857.1 - 0.64 9.2 44.9 0.26 10.5 11.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF2353 PF09789.4 CEP14857.1 - 0.75 8.9 34.9 8.3 5.5 24.1 2.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Reo_sigmaC PF04582.7 CEP14857.1 - 0.82 8.7 13.3 22 4.1 8.0 2.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein ERM PF00769.14 CEP14857.1 - 0.84 9.1 47.3 37 3.7 22.8 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF972 PF06156.8 CEP14857.1 - 1.1 9.6 38.4 1.4 9.2 3.2 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 CEP14857.1 - 1.2 8.9 41.2 0.55 9.9 7.8 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 CEP14857.1 - 1.3 9.3 55.7 2.1 8.7 5.0 4.8 1 1 3 4 4 4 0 Protein of unknown function (DUF904) Microtub_assoc PF07989.6 CEP14857.1 - 1.3 8.9 36.5 0.094 12.5 5.1 4.5 1 1 4 5 5 5 0 Microtubule associated TPR_MLP1_2 PF07926.7 CEP14857.1 - 1.4 8.6 50.9 1.4 8.6 10.8 3.3 1 1 1 2 2 1 0 TPR/MLP1/MLP2-like protein T2SF PF00482.18 CEP14857.1 - 1.5 8.7 9.4 6.8 6.6 1.0 3.0 1 1 0 3 3 3 0 Type II secretion system (T2SS), protein F Phage_GP20 PF06810.6 CEP14857.1 - 1.5 8.2 47.3 0.55 9.6 17.2 3.9 1 1 3 4 4 4 0 Phage minor structural protein GP20 MbeD_MobD PF04899.7 CEP14857.1 - 1.5 8.7 27.3 0.52 10.2 5.3 3.5 2 1 0 3 3 3 0 MbeD/MobD like FlaC_arch PF05377.6 CEP14857.1 - 2 8.4 36.0 0.63 9.9 2.7 5.7 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) KLRAQ PF10205.4 CEP14857.1 - 2 8.5 35.0 2.6 8.1 5.8 3.2 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF812 PF05667.6 CEP14857.1 - 2 6.8 41.0 3.2 6.1 28.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) BRE1 PF08647.6 CEP14857.1 - 2.1 8.4 42.4 1.3 9.0 8.9 3.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Ax_dynein_light PF10211.4 CEP14857.1 - 2.1 8.1 45.6 0.43 10.4 12.1 3.2 1 1 4 5 5 5 0 Axonemal dynein light chain TBPIP PF07106.8 CEP14857.1 - 2.2 7.7 45.4 7.2 6.1 4.7 3.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_25 PF13481.1 CEP14857.1 - 2.6 7.3 5.5 3.6 6.9 0.4 2.2 2 0 0 2 2 2 0 AAA domain CCDC155 PF14662.1 CEP14857.1 - 3.1 7.3 48.1 0.12 11.9 18.0 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Spc7 PF08317.6 CEP14857.1 - 4.5 5.8 44.7 1.3 7.6 9.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Mnd1 PF03962.10 CEP14857.1 - 4.8 6.8 44.2 18 4.9 18.5 2.8 1 1 1 2 2 2 0 Mnd1 family Seryl_tRNA_N PF02403.17 CEP14857.1 - 6.3 6.8 42.4 11 6.0 4.2 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Transposase_22 PF02994.9 CEP14857.1 - 6.5 5.1 32.2 15 3.9 22.2 1.6 1 1 0 1 1 1 0 L1 transposable element Atg14 PF10186.4 CEP14857.1 - 6.6 5.5 42.7 4.7 6.0 9.9 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 CEP14857.1 - 6.7 6.6 32.4 4 7.3 5.8 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein PspA_IM30 PF04012.7 CEP14857.1 - 9.1 5.5 40.5 1.7 7.9 6.6 3.2 1 1 0 2 2 2 0 PspA/IM30 family DUF1583 PF07622.6 CEP14858.1 - 0.032 12.6 0.0 0.038 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) DUF1746 PF08508.5 CEP14858.1 - 0.046 13.6 0.3 0.33 10.9 0.2 2.0 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1746) ABC_membrane PF00664.18 CEP14859.1 - 1.3e-97 326.5 29.2 4.9e-52 177.0 8.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP14859.1 - 9.2e-68 226.8 0.3 2e-35 122.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CEP14859.1 - 2.9e-11 43.8 0.0 0.14 12.0 0.0 4.3 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 CEP14859.1 - 4.8e-11 42.3 8.3 3.4e-05 23.1 0.4 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CEP14859.1 - 3e-10 39.2 3.7 0.00018 20.2 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 CEP14859.1 - 3.8e-09 36.7 2.1 0.0034 17.3 0.6 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CEP14859.1 - 2.6e-08 34.0 2.5 0.0083 16.2 0.2 4.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEP14859.1 - 2.9e-08 33.0 0.4 0.004 16.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 CEP14859.1 - 4.1e-07 30.2 0.2 0.15 12.2 0.0 4.1 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CEP14859.1 - 8.9e-07 28.2 0.3 0.0074 15.4 0.0 2.9 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CEP14859.1 - 6.6e-06 26.9 0.0 0.021 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.15 CEP14859.1 - 2.2e-05 23.3 0.2 0.098 11.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.1 CEP14859.1 - 5.2e-05 23.1 0.1 0.099 12.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CEP14859.1 - 8.9e-05 22.1 2.0 0.11 12.0 0.1 3.9 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CEP14859.1 - 0.0001 22.0 0.1 1.2 8.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CEP14859.1 - 0.0001 21.3 0.1 0.071 12.0 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CEP14859.1 - 0.00016 20.8 0.0 0.68 9.0 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin SbcCD_C PF13558.1 CEP14859.1 - 0.00042 20.1 1.4 1.5 8.8 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CEP14859.1 - 0.00047 19.6 0.6 0.43 9.9 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 CEP14859.1 - 0.00056 19.8 0.0 2.4 8.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CEP14859.1 - 0.0025 18.1 0.0 0.74 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 CEP14859.1 - 0.0026 17.4 0.2 0.12 12.0 0.0 2.8 2 0 0 2 2 2 1 Adenylylsulphate kinase MobB PF03205.9 CEP14859.1 - 0.0036 17.0 0.1 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CEP14859.1 - 0.0044 16.4 0.1 0.99 8.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 CEP14859.1 - 0.0047 16.8 0.1 2.1 8.3 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CEP14859.1 - 0.0077 15.7 0.2 2.1 7.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 CEP14859.1 - 0.0082 15.9 2.3 1.6 8.5 0.1 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF87 NB-ARC PF00931.17 CEP14859.1 - 0.0086 14.9 0.7 0.19 10.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 CEP14859.1 - 0.012 15.8 0.0 6.8 6.9 0.0 3.5 3 0 0 3 3 2 0 RNA helicase AAA_25 PF13481.1 CEP14859.1 - 0.013 14.9 0.0 2.8 7.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 CEP14859.1 - 0.017 14.8 0.2 1 8.9 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 CEP14859.1 - 0.019 14.9 0.0 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 CEP14859.1 - 0.02 13.9 0.4 1.7 7.5 0.0 2.7 2 1 0 2 2 2 0 Septin Synapsin_N PF10581.4 CEP14859.1 - 0.032 14.0 0.0 9.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Synapsin N-terminal Miro PF08477.8 CEP14859.1 - 0.033 14.6 0.0 17 5.9 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Mg_chelatase PF01078.16 CEP14859.1 - 0.044 12.9 0.0 2 7.5 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 CEP14859.1 - 0.079 12.5 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.12 CEP14859.1 - 0.33 10.3 3.7 29 3.9 0.1 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein IKI3 PF04762.7 CEP14860.1 - 1e-278 927.0 0.0 1.5e-278 926.5 0.0 1.2 1 0 0 1 1 1 1 IKI3 family WD40 PF00400.27 CEP14860.1 - 0.079 12.8 1.9 88 3.2 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat Proteasome PF00227.21 CEP14861.1 - 3.2e-17 62.4 0.2 1.6e-08 34.0 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Epiglycanin_TR PF05647.6 CEP14862.1 - 0.41 10.4 6.5 0.57 10.0 4.5 1.1 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Aa_trans PF01490.13 CEP14863.1 - 8.1e-62 209.0 23.9 1.1e-61 208.5 16.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CEP14863.1 - 0.00038 19.3 21.2 0.0051 15.6 6.3 3.2 3 0 0 3 3 3 3 Tryptophan/tyrosine permease family MitMem_reg PF13012.1 CEP14864.1 - 2.8e-24 85.3 0.0 4.4e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CEP14864.1 - 2.3e-13 49.8 0.0 3.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RepA_C PF04796.7 CEP14864.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Plasmid encoded RepA protein GAT PF03127.9 CEP14864.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 GAT domain Fungal_trans PF04082.13 CEP14865.1 - 8.5e-38 129.7 0.8 2.9e-37 127.9 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP14865.1 - 3.3e-08 33.3 12.5 6e-08 32.4 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syndecan PF01034.15 CEP14866.1 - 0.0075 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain AA_kinase PF00696.23 CEP14867.1 - 3.1e-41 141.5 0.1 4.2e-41 141.0 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 CEP14867.1 - 2.1e-12 46.2 1.0 5.4e-07 28.9 0.1 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 CEP14867.1 - 5.9e-11 41.7 3.1 8.1e-08 31.6 0.7 2.7 2 0 0 2 2 2 2 ACT domain DUF334 PF03904.8 CEP14867.1 - 0.0094 15.2 0.3 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF334) FIST PF08495.5 CEP14868.1 - 4.9e-07 29.0 0.0 3e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 FIST N domain ATP-gua_PtransN PF02807.10 CEP14868.1 - 0.0023 18.0 0.2 0.0052 16.8 0.1 1.7 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DEAD PF00270.24 CEP14869.1 - 5.5e-41 139.8 0.0 1.1e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP14869.1 - 2e-21 75.6 0.0 4.6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CEP14869.1 - 1.1e-17 63.2 0.1 2.4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CEP14869.1 - 6.8e-05 22.7 3.4 7e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEP14869.1 - 0.096 12.8 1.1 1.3 9.1 0.8 2.7 1 1 0 1 1 1 0 AAA domain DUF2358 PF10184.4 CEP14870.1 - 0.0016 18.3 0.0 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) SnoaL PF07366.7 CEP14870.1 - 0.051 13.1 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF3472 PF11958.3 CEP14871.1 - 1.2e-28 100.7 5.7 1.5e-28 100.4 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) BNR PF02012.15 CEP14871.1 - 0.00054 19.3 0.4 0.0023 17.5 0.3 2.2 1 0 0 1 1 1 1 BNR/Asp-box repeat Pkinase PF00069.20 CEP14872.1 - 3.5e-68 229.5 0.0 4.2e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14872.1 - 1.9e-33 115.6 0.0 2.5e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14872.1 - 6.2e-08 31.9 0.0 8.3e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CEP14872.1 - 6.4e-06 26.5 0.1 1.3e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 CEP14872.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Transketolase_N PF00456.16 CEP14873.1 - 3.3e-153 509.3 0.0 4.1e-153 509.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CEP14873.1 - 9.3e-45 152.2 0.0 1.5e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CEP14873.1 - 2.6e-09 37.0 0.0 7.9e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CEP14873.1 - 2.7e-06 26.5 0.0 0.00017 20.6 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CEP14873.1 - 0.027 13.2 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Terpene_synth PF01397.16 CEP14873.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Alba PF01918.16 CEP14873.1 - 0.44 10.1 1.9 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Alba F5_F8_type_C PF00754.20 CEP14874.1 - 0.00038 20.2 0.2 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain Aa_trans PF01490.13 CEP14875.1 - 5e-54 183.3 35.4 2.6e-53 181.0 24.5 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GATA PF00320.22 CEP14876.1 - 1.1e-17 63.0 2.4 2.3e-17 62.0 1.7 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CEP14876.1 - 1.4e-14 53.3 0.8 2.7e-14 52.4 0.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF2935 PF11155.3 CEP14877.1 - 0.94 9.5 4.8 5.5 7.0 0.9 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Amidohydro_1 PF01979.15 CEP14878.1 - 5.9e-42 144.4 0.0 7.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CEP14878.1 - 5.1e-06 26.2 0.1 2.2e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CEP14878.1 - 6.1e-06 25.7 0.1 0.077 12.2 0.0 3.0 3 1 0 4 4 4 2 Amidohydrolase family Amidohydro_4 PF13147.1 CEP14878.1 - 1.1e-05 25.6 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase PS_Dcarbxylase PF02666.10 CEP14881.1 - 1.2e-75 253.2 0.0 1.9e-73 246.0 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DNA_pol_E_B PF04042.11 CEP14882.1 - 1.7e-49 167.9 0.1 2.6e-49 167.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Phosphodiest PF01663.17 CEP14883.1 - 2.5e-78 263.9 1.1 2.9e-78 263.7 0.7 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CEP14883.1 - 4.6e-06 26.0 0.7 0.00061 19.0 0.3 2.6 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 CEP14883.1 - 0.044 13.4 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 PglZ domain BTB PF00651.26 CEP14884.1 - 3e-18 65.8 0.3 5.6e-17 61.7 0.0 2.7 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.10 CEP14884.1 - 1.6e-09 37.4 0.0 0.0001 22.0 0.0 2.7 2 0 0 2 2 2 2 BTB And C-terminal Kelch LIN37 PF15306.1 CEP14884.1 - 0.0051 16.8 0.3 0.0089 16.0 0.2 1.3 1 0 0 1 1 1 1 LIN37 BSP_II PF05432.6 CEP14884.1 - 0.15 11.2 5.0 0.27 10.4 3.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 CEP14884.1 - 0.56 9.3 7.1 0.91 8.6 5.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Na_Ca_ex PF01699.19 CEP14885.1 - 5.1e-39 133.0 28.1 5.9e-20 71.2 4.8 2.8 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 CEP14885.1 - 1.3 8.4 14.5 2.4 7.5 2.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MOZ_SAS PF01853.13 CEP14886.1 - 7.7e-86 286.1 0.6 1.3e-85 285.3 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family Dehydrin PF00257.14 CEP14886.1 - 0.07 13.4 1.9 0.14 12.4 1.3 1.5 1 0 0 1 1 1 0 Dehydrin Macoilin PF09726.4 CEP14886.1 - 0.68 8.1 7.4 1 7.5 5.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF592 PF04574.8 CEP14887.1 - 0.066 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) HTH_23 PF13384.1 CEP14887.1 - 0.17 11.5 0.8 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Aldo_ket_red PF00248.16 CEP14889.1 - 4.1e-56 189.8 0.0 4.7e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Prothymosin PF03247.9 CEP14890.1 - 0.00064 19.8 5.5 0.00097 19.2 3.8 1.3 1 0 0 1 1 1 1 Prothymosin/parathymosin family Nucleo_P87 PF07267.6 CEP14890.1 - 0.0099 14.6 2.0 0.013 14.2 1.4 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 FLO_LFY PF01698.11 CEP14890.1 - 0.054 12.3 4.2 0.075 11.8 2.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 CEP14890.1 - 0.069 11.1 2.9 0.072 11.1 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 CEP14890.1 - 2.6 8.4 10.5 5.2 7.4 7.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HMG_box PF00505.14 CEP14891.1 - 1.9e-19 69.7 2.4 4.3e-19 68.5 1.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP14891.1 - 2.9e-08 33.9 1.2 2.9e-08 33.9 0.8 2.5 2 0 0 2 2 2 1 HMG-box domain Pribosyltran PF00156.22 CEP14892.1 - 2.6e-11 43.3 0.1 3.7e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 CEP14892.1 - 0.039 13.2 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Lectin_C PF00059.16 CEP14893.1 - 0.0084 16.7 0.1 0.085 13.5 0.1 2.2 1 1 0 1 1 1 1 Lectin C-type domain NAP PF00956.13 CEP14894.1 - 0.0041 16.2 1.1 0.0081 15.3 0.8 1.4 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) PH PF00169.24 CEP14894.1 - 0.0083 16.3 1.1 0.054 13.7 0.0 2.9 3 0 0 3 3 3 1 PH domain Nucleoplasmin PF03066.10 CEP14894.1 - 0.38 10.2 4.0 0.79 9.2 2.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Chromo PF00385.19 CEP14895.1 - 2e-07 30.5 0.2 4.1e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FMO-like PF00743.14 CEP14896.1 - 4.7e-24 84.4 0.1 1.5e-23 82.8 0.1 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CEP14896.1 - 4.5e-20 72.5 0.0 7.6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP14896.1 - 5.5e-11 42.3 0.0 1.5e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CEP14896.1 - 8.7e-08 31.4 0.1 1.3e-06 27.6 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CEP14896.1 - 0.00011 22.1 0.0 0.00036 20.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP14896.1 - 0.0016 17.3 0.0 0.015 14.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CEP14896.1 - 0.0035 17.1 0.0 0.11 12.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 CEP14896.1 - 0.01 14.9 0.1 0.63 9.0 0.0 2.4 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 CEP14896.1 - 0.096 11.5 0.2 7.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-H2C2_2 PF13465.1 CEP14897.1 - 1.3e-12 47.2 18.0 1e-06 28.7 3.4 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP14897.1 - 4e-09 36.1 11.7 3.4e-05 23.8 1.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP14897.1 - 2.6e-08 33.7 9.1 9.8e-06 25.6 0.7 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type DUF2225 PF09986.4 CEP14897.1 - 0.13 11.6 1.7 1.7 8.0 1.2 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Virul_Fac PF10139.4 CEP14898.1 - 0.0023 15.9 0.2 0.0031 15.5 0.1 1.1 1 0 0 1 1 1 1 Putative bacterial virulence factor TPK_catalytic PF04263.11 CEP14900.1 - 4.8e-26 90.7 0.1 6.7e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CEP14900.1 - 4.3e-19 67.9 0.0 7.5e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain COG2 PF06148.6 CEP14900.1 - 0.066 13.0 0.1 0.091 12.6 0.1 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cpn10 PF00166.16 CEP14901.1 - 1.7e-28 98.4 0.1 1.9e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit RhoGAP PF00620.22 CEP14902.1 - 3.1e-31 108.0 0.0 4.6e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.15 CEP14903.1 - 4.1e-29 101.7 0.2 8.2e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 CEP14903.1 - 6.3e-21 74.7 0.0 2.8e-20 72.6 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 CEP14903.1 - 4.5e-11 42.3 0.1 9.7e-11 41.2 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 CEP14903.1 - 0.013 15.7 0.4 0.094 12.9 0.0 2.7 2 1 0 2 2 2 0 PH domain EI24 PF07264.6 CEP14906.1 - 7.2e-13 48.4 11.8 1e-12 47.9 8.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4137 PF13593.1 CEP14906.1 - 0.0033 16.5 1.3 0.0033 16.5 0.9 1.8 2 0 0 2 2 2 1 SBF-like CPA transporter family (DUF4137) MFS_1 PF07690.11 CEP14906.1 - 0.014 14.0 7.8 0.026 13.2 5.4 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily MMPL PF03176.10 CEP14906.1 - 0.095 11.3 0.9 0.18 10.5 0.6 1.4 1 0 0 1 1 1 0 MMPL family DUF2079 PF09852.4 CEP14906.1 - 0.12 11.0 16.8 0.85 8.2 11.7 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF4231 PF14015.1 CEP14906.1 - 1.5 8.8 5.0 29 4.7 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Pkinase PF00069.20 CEP14907.1 - 4.4e-69 232.5 0.0 6.4e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14907.1 - 8.9e-35 120.0 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14907.1 - 5.8e-05 22.1 0.0 8.9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP14907.1 - 0.078 12.6 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RGS PF00615.14 CEP14908.1 - 7.7e-09 35.6 0.0 3.4e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Metallophos_2 PF12850.2 CEP14909.1 - 6.4e-09 35.8 0.2 1.6e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CEP14909.1 - 2.2e-06 27.2 2.5 0.033 13.5 0.1 3.4 3 1 0 3 3 3 2 Calcineurin-like phosphoesterase PC-Esterase PF13839.1 CEP14909.1 - 0.014 15.1 0.0 0.47 10.2 0.0 2.8 4 0 0 4 4 4 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p EF-hand_7 PF13499.1 CEP14910.1 - 2.2e-09 37.3 4.9 7.8e-09 35.5 3.4 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CEP14910.1 - 2.4e-06 26.9 3.7 7e-06 25.5 0.5 2.9 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CEP14910.1 - 0.00039 19.5 0.2 0.00039 19.5 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 CEP14910.1 - 0.0016 17.7 1.9 0.0085 15.4 0.0 3.0 3 0 0 3 3 3 1 EF hand DUF3139 PF11337.3 CEP14910.1 - 0.05 13.8 0.9 3.8 7.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) Ribosomal_S3Ae PF01015.13 CEP14911.1 - 3.6e-74 248.3 6.2 4.1e-74 248.1 4.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family FokI_N PF02981.10 CEP14911.1 - 0.051 13.1 0.2 0.089 12.4 0.2 1.5 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain DUF3571 PF12095.3 CEP14911.1 - 0.072 13.3 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) Kelch_3 PF13415.1 CEP14911.1 - 0.14 12.3 0.0 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF496 PF04363.7 CEP14911.1 - 0.94 9.3 4.8 10 5.9 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF496) HTH_28 PF13518.1 CEP14913.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1798 PF08807.5 CEP14913.1 - 0.18 11.5 2.3 1.4 8.6 0.5 2.8 2 1 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) RyR PF02026.11 CEP14913.1 - 0.26 11.3 7.4 1.2 9.1 1.7 3.5 1 1 2 3 3 3 0 RyR domain GCV_H PF01597.14 CEP14914.1 - 0.056 13.1 0.2 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein HMG_box PF00505.14 CEP14915.1 - 1.7e-16 60.2 0.1 1.7e-16 60.2 0.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP14915.1 - 1.5e-11 44.5 1.7 1.5e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 HMG-box domain BRE1 PF08647.6 CEP14915.1 - 0.39 10.7 3.7 0.3 11.0 0.9 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CTP_transf_2 PF01467.21 CEP14916.1 - 9.3e-26 90.7 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Aminotran_1_2 PF00155.16 CEP14917.1 - 6.9e-59 199.6 0.0 8.2e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEP14917.1 - 3.9e-06 26.2 0.0 7.1e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 CEP14917.1 - 0.0057 15.2 0.0 0.012 14.1 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 CEP14917.1 - 0.036 13.1 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CEP14917.1 - 0.063 12.0 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Methyltransf_32 PF13679.1 CEP14918.1 - 1.5e-26 92.7 0.1 2.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP14918.1 - 0.00022 20.8 0.1 0.00058 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP14918.1 - 0.00074 19.2 0.0 0.0022 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP14918.1 - 0.00091 18.6 0.1 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CEP14918.1 - 0.00095 19.7 0.0 0.0027 18.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP14918.1 - 0.1 12.9 0.2 0.69 10.3 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 CEP14918.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L6 PF00347.18 CEP14919.1 - 2.3e-24 85.6 0.4 1.1e-11 45.0 0.0 3.2 2 1 0 2 2 2 2 Ribosomal protein L6 Ank_2 PF12796.2 CEP14920.1 - 5.2e-81 267.0 13.7 1.2e-19 70.4 0.0 6.3 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 CEP14920.1 - 5.4e-74 240.5 19.8 1.4e-10 40.4 0.1 9.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 CEP14920.1 - 4.6e-63 208.5 15.3 3e-15 56.2 0.1 8.3 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP14920.1 - 1.3e-58 193.6 17.4 2.8e-09 36.9 0.2 8.7 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP14920.1 - 2.4e-57 185.1 5.4 3.9e-07 29.6 0.0 9.9 9 0 0 9 9 9 9 Ankyrin repeat Hydrolase_4 PF12146.3 CEP14920.1 - 0.082 12.7 0.9 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Putative lysophospholipase zf-C2H2_2 PF12756.2 CEP14921.1 - 5.9e-34 116.2 12.6 1.2e-23 83.0 1.8 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CEP14921.1 - 1.3e-06 28.3 4.6 1.2e-05 25.3 0.6 4.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP14921.1 - 8e-06 25.8 12.8 0.00034 20.7 0.5 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CEP14921.1 - 0.00011 22.3 15.2 0.005 17.0 0.5 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP14921.1 - 0.00034 20.7 26.0 0.00039 20.6 1.0 5.5 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-BED PF02892.10 CEP14921.1 - 0.044 13.5 0.2 0.044 13.5 0.2 3.9 4 0 0 4 4 4 0 BED zinc finger PyrI_C PF02748.10 CEP14921.1 - 0.045 13.1 2.6 0.066 12.6 0.0 2.7 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Levi_coat PF01819.12 CEP14921.1 - 0.12 11.9 0.3 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 Levivirus coat protein zf-C2HC5 PF06221.8 CEP14921.1 - 3.1 7.6 6.6 6.9 6.5 0.1 3.3 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type Syntaxin_2 PF14523.1 CEP14922.1 - 1.1e-26 92.8 6.5 3.2e-26 91.3 2.4 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 CEP14922.1 - 2.6e-08 33.4 4.4 2.6e-08 33.4 3.0 2.8 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CEP14922.1 - 1.4e-07 31.5 0.9 1.4e-07 31.5 0.6 3.0 2 1 0 2 2 2 1 Syntaxin V-SNARE PF05008.10 CEP14922.1 - 0.027 14.6 1.7 0.027 14.6 1.1 3.1 3 2 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus THOC7 PF05615.8 CEP14922.1 - 0.5 10.6 12.2 2.2 8.5 6.9 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 LMBR1 PF04791.11 CEP14922.1 - 2.8 6.4 4.8 4.6 5.7 3.3 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Methyltransf_11 PF08241.7 CEP14923.1 - 2.6e-15 56.6 0.0 7.2e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP14923.1 - 1.3e-13 51.0 0.0 1.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP14923.1 - 2.2e-13 50.0 0.0 1.7e-12 47.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP14923.1 - 2.9e-11 43.6 0.0 7.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP14923.1 - 3.3e-08 33.8 0.0 9.8e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP14923.1 - 3.9e-08 33.8 0.0 1.1e-07 32.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP14923.1 - 7.7e-08 31.7 0.0 2.5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CEP14923.1 - 7.9e-06 25.0 0.0 0.00017 20.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 CEP14923.1 - 1.5e-05 24.2 0.1 5e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 CEP14923.1 - 2e-05 23.8 0.0 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_8 PF05148.10 CEP14923.1 - 5.5e-05 22.9 0.0 7.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 CEP14923.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CEP14923.1 - 0.0039 17.1 0.1 0.011 15.7 0.1 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.13 CEP14923.1 - 0.01 15.1 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 CEP14923.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 CEP14923.1 - 0.035 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RabGAP-TBC PF00566.13 CEP14924.1 - 1.5e-16 60.4 11.7 2.4e-10 40.2 0.5 2.9 2 1 1 3 3 3 2 Rab-GTPase-TBC domain Pox_A30L_A26L PF06086.7 CEP14924.1 - 0.036 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Zn_clus PF00172.13 CEP14925.1 - 0.00097 18.9 18.5 0.0015 18.4 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 CEP14926.1 - 0.063 12.7 4.7 0.11 11.9 3.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.6 CEP14926.1 - 0.076 12.3 4.3 0.12 11.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Pex24p PF06398.6 CEP14927.1 - 5.5 5.6 10.1 0.065 12.0 0.5 2.4 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Homeobox PF00046.24 CEP14928.1 - 4.3e-17 61.4 1.5 9.7e-17 60.3 1.0 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP14928.1 - 0.086 12.5 4.2 0.18 11.5 0.1 2.7 2 0 0 2 2 2 0 Homeobox KN domain NAD_binding_1 PF00175.16 CEP14931.1 - 2e-31 108.7 0.0 3.4e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEP14931.1 - 1.3e-21 76.5 0.0 2.4e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CEP14931.1 - 4.3e-09 36.4 0.0 8.9e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CEP14931.1 - 0.0066 16.4 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Velvet PF11754.3 CEP14932.1 - 4.1e-50 170.2 2.5 1.6e-49 168.3 1.7 1.8 1 1 0 1 1 1 1 Velvet factor DUF4589 PF15252.1 CEP14932.1 - 0.28 10.9 5.4 0.54 10.0 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) SRF-TF PF00319.13 CEP14933.1 - 2.2e-22 78.0 0.2 3.2e-22 77.4 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF605 PF04652.11 CEP14933.1 - 0.0038 16.6 27.3 0.006 16.0 18.9 1.3 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 CEP14933.1 - 8.7 4.4 41.6 14 3.7 28.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 CEP14934.1 - 1.7e-23 82.8 43.7 2.9e-12 45.9 13.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP14934.1 - 3.3e-08 32.5 25.2 3.6e-07 29.1 7.7 2.7 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 CEP14934.1 - 0.065 13.0 0.2 0.065 13.0 0.1 3.7 5 0 0 5 5 5 0 MFS_1 like family Bac_export_2 PF01312.14 CEP14934.1 - 0.28 10.0 1.3 0.42 9.4 0.3 1.7 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF3712 PF12505.3 CEP14935.1 - 4.3e-70 233.5 34.3 1e-21 77.2 0.8 6.3 7 0 0 7 7 7 4 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CEP14935.1 - 3.5e-09 36.9 9.1 0.54 10.6 0.3 7.8 7 0 0 7 7 7 3 Late embryogenesis abundant protein Sigma_reg_N PF13800.1 CEP14935.1 - 0.013 15.5 1.1 0.033 14.1 0.8 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Chordopox_A13L PF05961.6 CEP14935.1 - 0.48 10.3 4.0 0.97 9.4 2.8 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Rifin_STEVOR PF02009.11 CEP14935.1 - 0.71 9.4 5.1 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Rifin/stevor family DUF4504 PF14953.1 CEP14936.1 - 0.055 12.7 0.0 0.059 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) zf-RVT PF13966.1 CEP14937.1 - 5.2e-08 33.0 0.6 9.8e-08 32.2 0.4 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase EI24 PF07264.6 CEP14938.1 - 0.0071 15.8 11.5 0.02 14.2 8.0 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.1 CEP14938.1 - 0.06 13.2 0.4 0.78 9.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4112) CBM_14 PF01607.19 CEP14939.1 - 4.4e-08 32.9 0.2 5.6e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Pkinase PF00069.20 CEP14940.1 - 9.2e-50 169.2 0.0 1.5e-49 168.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14940.1 - 4.1e-23 81.7 0.0 5.9e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14940.1 - 0.002 17.1 0.0 0.004 16.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP14940.1 - 0.04 13.6 0.0 0.6 9.8 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family ACBP PF00887.14 CEP14941.1 - 5.4e-27 93.2 0.1 1.8e-26 91.6 0.1 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4611 PF15387.1 CEP14941.1 - 0.0014 18.7 2.8 0.0014 18.7 1.9 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) ANAPC15 PF15243.1 CEP14941.1 - 0.3 11.1 0.1 0.3 11.1 0.1 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 15 AATF-Che1 PF13339.1 CEP14941.1 - 0.55 10.3 9.9 0.11 12.6 1.5 3.1 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Gon7 PF08738.5 CEP14941.1 - 9.3 6.2 12.3 0.16 11.9 1.4 3.2 3 1 1 4 4 4 0 Gon7 family DUF974 PF06159.8 CEP14942.1 - 1.4e-76 257.2 0.0 2.1e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.2 CEP14942.1 - 3.9e-08 32.9 0.6 6.1e-06 25.7 0.0 3.0 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 Transglut_C PF00927.17 CEP14942.1 - 0.00031 20.7 0.1 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain DUF4449 PF14613.1 CEP14943.1 - 3.4e-11 43.3 0.5 3.4e-11 43.3 0.4 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.20 CEP14943.1 - 1.6e-05 24.3 0.1 4.5e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain CotH PF08757.6 CEP14944.1 - 8.1e-37 127.1 0.0 1.2e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 CotH protein Pkinase PF00069.20 CEP14946.1 - 1.4e-61 207.9 0.0 2.5e-61 207.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP14946.1 - 2e-45 154.9 0.0 3.9e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP14946.1 - 2.4e-05 23.4 0.0 5.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like HALZ PF02183.13 CEP14946.1 - 0.046 13.4 1.6 0.12 12.1 1.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF972 PF06156.8 CEP14946.1 - 0.44 10.9 4.3 1.5 9.2 3.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIVA PF05103.8 CEP14946.1 - 0.95 9.5 6.7 3.3 7.7 4.6 1.9 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.17 CEP14947.1 - 6.8e-51 173.0 3.2 1e-50 172.5 2.2 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 CEP14947.1 - 1.5e-09 37.4 0.1 3.5e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 CEP14947.1 - 1.3e-06 28.8 0.3 4.1e-06 27.1 0.2 1.9 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Motile_Sperm PF00635.21 CEP14947.1 - 0.0044 16.6 0.6 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Ribosomal_L24e PF01246.15 CEP14948.1 - 4.2e-24 84.1 0.2 4.2e-24 84.1 0.1 1.8 2 1 1 3 3 3 1 Ribosomal protein L24e Ribosomal_S4e PF00900.15 CEP14949.1 - 1.2e-32 111.3 1.6 4.1e-32 109.6 0.4 2.2 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CEP14949.1 - 3.9e-19 68.2 5.7 1.8e-18 66.0 4.4 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 CEP14949.1 - 2.5e-06 26.8 0.0 7.1e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CEP14949.1 - 0.00011 21.7 4.9 0.00011 21.7 3.4 3.4 4 1 0 4 4 4 1 KOW motif HSF_DNA-bind PF00447.12 CEP14950.1 - 5.9e-37 125.9 2.0 2.5e-36 123.9 1.4 2.1 1 0 0 1 1 1 1 HSF-type DNA-binding Syntaxin_2 PF14523.1 CEP14950.1 - 0.026 14.5 1.8 0.026 14.5 1.3 1.9 2 0 0 2 2 2 0 Syntaxin-like protein DUF310 PF03750.8 CEP14950.1 - 0.039 14.1 0.6 0.064 13.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF310) SPARC_Ca_bdg PF10591.4 CEP14950.1 - 0.05 13.6 0.3 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ALIX_LYPXL_bnd PF13949.1 CEP14950.1 - 0.08 11.8 7.3 0.081 11.8 2.5 2.1 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.4 CEP14950.1 - 1.4 8.9 9.1 0.057 13.4 2.4 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein CAP_GLY PF01302.20 CEP14951.1 - 2.5e-18 65.5 0.1 4e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF2762 PF10960.3 CEP14951.1 - 4.1 7.1 6.4 0.25 11.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Cse1 PF08506.5 CEP14952.1 - 2.1e-141 470.7 4.5 1.5e-140 467.9 2.8 2.1 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 CEP14952.1 - 3.6e-120 401.2 0.3 6.6e-120 400.3 0.2 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus WD40 PF00400.27 CEP14952.1 - 3.1e-38 128.2 17.9 4.8e-10 38.9 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat IBN_N PF03810.14 CEP14952.1 - 5.8e-14 51.7 1.1 1.5e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain eIF2A PF08662.6 CEP14952.1 - 1.7e-05 24.5 0.3 0.021 14.5 0.1 3.9 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A HEAT_2 PF13646.1 CEP14952.1 - 0.0016 18.7 1.1 3.8 7.8 0.0 4.9 5 1 1 6 6 6 1 HEAT repeats HIRA_B PF09453.5 CEP14952.1 - 0.01 15.3 0.5 0.026 14.0 0.4 1.6 1 0 0 1 1 1 0 HIRA B motif Xpo1 PF08389.7 CEP14952.1 - 0.016 15.1 3.1 1.2 9.0 0.0 4.1 2 2 2 4 4 4 0 Exportin 1-like protein PD40 PF07676.7 CEP14952.1 - 0.048 13.3 2.9 0.17 11.6 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 CEP14952.1 - 0.067 12.6 0.0 0.34 10.4 0.0 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.2 CEP14953.1 - 8.5e-09 35.0 2.5 1.8e-08 34.0 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP14953.1 - 7.7e-05 22.2 1.7 9e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 F-box domain CBFB_NFYA PF02045.10 CEP14953.1 - 0.019 15.4 2.5 0.019 15.4 1.7 1.8 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LRR_4 PF12799.2 CEP14953.1 - 0.024 14.2 6.9 6.2 6.5 1.3 4.8 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.1 CEP14953.1 - 0.028 14.1 0.1 0.085 12.5 0.1 1.8 1 0 0 1 1 1 0 F-box-like domain SNF2_N PF00176.18 CEP14953.1 - 0.062 12.0 0.2 0.11 11.2 0.1 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Fungal_trans PF04082.13 CEP14954.1 - 1.2e-26 93.1 0.9 5.1e-26 91.0 0.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP14954.1 - 6.3e-11 42.0 12.4 1.7e-10 40.6 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suf PF05843.9 CEP14954.1 - 0.65 9.6 29.7 2.7 7.6 2.8 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PRP1_N PF06424.7 CEP14954.1 - 0.89 9.8 17.9 0.11 12.7 5.7 2.5 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal PAT1 PF09770.4 CEP14954.1 - 1.3 7.1 54.8 0.37 8.9 24.5 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Herpes_UL87 PF03043.9 CEP14954.1 - 3.8 5.7 13.4 6.9 4.9 9.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family RNA_pol_Rbc25 PF08292.7 CEP14954.1 - 6.8 6.9 12.9 0.51 10.5 5.0 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Zip PF02535.17 CEP14954.1 - 8.1 5.3 11.0 0.99 8.3 0.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter SOBP PF15279.1 CEP14954.1 - 8.3 6.6 35.2 2.5 8.3 10.4 2.7 3 0 0 3 3 3 0 Sine oculis-binding protein Not1 PF04054.10 CEP14955.1 - 7.2e-134 446.3 10.3 8.3e-134 446.2 4.6 2.6 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CEP14955.1 - 1.9e-46 157.3 8.5 1.9e-46 157.3 5.9 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3819) DDE_3 PF13358.1 CEP14957.1 - 7.7e-32 110.0 0.0 1.3e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 CEP14957.1 - 2.2e-05 24.3 0.1 5.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 CEP14957.1 - 0.0016 17.9 0.3 0.095 12.3 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP14957.1 - 0.0041 17.0 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP14957.1 - 0.0094 16.0 0.1 8 6.6 0.0 2.9 1 1 2 3 3 3 2 Winged helix-turn helix HTH_7 PF02796.10 CEP14957.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase rve PF00665.21 CEP14957.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DDE_1 PF03184.14 CEP14957.1 - 0.032 13.3 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_32 PF13565.1 CEP14957.1 - 0.033 14.9 0.7 0.12 13.1 0.0 2.3 2 1 1 3 3 3 0 Homeodomain-like domain Pectate_lyase_2 PF06917.7 CEP14957.1 - 0.05 11.8 0.0 0.11 10.6 0.0 1.5 2 0 0 2 2 2 0 Periplasmic pectate lyase ADH_N PF08240.7 CEP14959.1 - 5.9e-25 87.1 6.1 9.6e-25 86.4 4.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP14959.1 - 5.8e-17 61.4 0.0 9.3e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEP14959.1 - 9.1e-05 21.6 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 CEP14959.1 - 0.0011 19.8 0.0 0.0019 19.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 CEP14959.1 - 0.006 16.4 0.1 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 CEP14959.1 - 0.011 15.3 0.1 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CEP14959.1 - 0.17 11.5 0.3 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FSH1 PF03959.8 CEP14960.1 - 1.9e-53 181.1 0.0 2.5e-52 177.4 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CEP14960.1 - 0.0028 17.4 0.0 0.0058 16.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AP_endonuc_2_N PF07582.7 CEP14960.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus Abhydrolase_2 PF02230.11 CEP14960.1 - 0.11 11.8 1.4 12 5.2 0.6 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Zn_clus PF00172.13 CEP14961.1 - 7.9e-05 22.4 14.7 0.00013 21.7 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L16 PF00252.13 CEP14962.1 - 5.6e-44 149.1 1.2 7.1e-44 148.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Cpn60_TCP1 PF00118.19 CEP14964.1 - 5.9e-143 477.0 5.1 6.7e-143 476.8 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 CEP14964.1 - 0.067 12.8 0.1 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein zf-C2H2 PF00096.21 CEP14965.1 - 1.2e-08 34.7 9.3 0.00052 20.1 1.6 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP14965.1 - 2.8e-08 33.5 5.7 0.00017 21.6 0.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP14965.1 - 0.0012 19.0 2.9 0.0012 19.0 2.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEP14965.1 - 0.0098 15.7 2.0 0.37 10.7 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CEP14965.1 - 0.067 12.8 2.1 0.075 12.7 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PALP PF00291.20 CEP14966.1 - 7.2e-70 235.6 3.9 8.9e-70 235.3 2.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4070 PF13282.1 CEP14967.1 - 0.068 12.7 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) zf-RING_2 PF13639.1 CEP14968.1 - 3.3e-05 23.6 1.4 0.00011 21.9 1.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP14968.1 - 4.1e-05 23.5 1.7 0.00012 22.0 1.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP14968.1 - 0.01 15.4 2.2 0.01 15.4 1.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP14968.1 - 0.014 15.0 0.8 0.059 13.1 0.6 2.2 1 0 0 1 1 1 0 RING-type zinc-finger Prefoldin_2 PF01920.15 CEP14968.1 - 0.02 14.6 5.0 0.02 14.6 3.4 6.5 3 2 3 6 6 6 0 Prefoldin subunit UCR_hinge PF02320.11 CEP14968.1 - 0.021 14.7 2.2 0.76 9.7 0.1 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein zf-C3HC4_3 PF13920.1 CEP14968.1 - 0.031 13.9 1.3 0.031 13.9 0.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4248 PF14053.1 CEP14968.1 - 0.083 12.4 6.3 0.085 12.4 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) Ole-e-6 PF09253.5 CEP14968.1 - 0.69 9.6 6.6 0.15 11.7 1.6 2.2 2 0 0 2 2 2 0 Pollen allergen ole e 6 Zn_protease PF05618.6 CEP14968.1 - 0.77 9.4 7.1 0.19 11.3 0.7 2.5 2 1 0 2 2 2 0 Putative ATP-dependant zinc protease THOC7 PF05615.8 CEP14968.1 - 1.5 9.0 34.3 0.06 13.6 8.1 3.9 2 2 1 3 3 3 0 Tho complex subunit 7 zf-RING_5 PF14634.1 CEP14968.1 - 1.6 8.5 9.9 0.066 12.9 1.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain CENP-F_leu_zip PF10473.4 CEP14968.1 - 4 7.3 48.3 0.094 12.5 11.6 4.0 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CEP14968.1 - 4.3 6.4 19.8 0.85 8.7 3.7 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein GAS PF13851.1 CEP14968.1 - 5 6.2 52.3 0.57 9.3 10.9 4.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CEP14968.1 - 8.3 5.3 48.5 4.8 6.1 8.2 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 AIP3 PF03915.8 CEP14969.1 - 1.5e-91 307.4 34.7 7.3e-91 305.1 24.1 2.0 1 1 0 1 1 1 1 Actin interacting protein 3 F-box PF00646.28 CEP14970.1 - 0.019 14.5 0.2 0.095 12.3 0.0 2.3 2 0 0 2 2 2 0 F-box domain DUF1411 PF07199.6 CEP14970.1 - 0.025 14.0 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) COG5 PF10392.4 CEP14971.1 - 0.096 12.6 2.8 0.49 10.3 0.1 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 UBX PF00789.15 CEP14972.1 - 2.4e-15 56.3 0.4 5e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 CEP14972.1 - 2e-06 27.4 0.2 3.1e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain PLRV_ORF5 PF01690.12 CEP14972.1 - 0.43 9.6 12.3 0.5 9.4 8.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Borrelia_P83 PF05262.6 CEP14972.1 - 0.89 7.7 26.5 1.1 7.4 18.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SOBP PF15279.1 CEP14972.1 - 0.96 9.7 8.5 1.2 9.4 5.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DDRGK PF09756.4 CEP14972.1 - 6.1 6.2 31.1 0.53 9.6 5.9 2.1 1 1 1 2 2 2 0 DDRGK domain Ycf1 PF05758.7 CEP14972.1 - 8.3 3.9 12.9 9.3 3.8 8.9 1.2 1 0 0 1 1 1 0 Ycf1 SPRY PF00622.23 CEP14973.1 - 6.5e-21 74.6 0.4 9.7e-21 74.1 0.3 1.3 1 0 0 1 1 1 1 SPRY domain RabGAP-TBC PF00566.13 CEP14975.1 - 1.7e-53 181.2 0.8 1.7e-53 181.2 0.5 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ala_racemase_N PF01168.15 CEP14975.1 - 1.1e-44 152.5 0.0 2.1e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA_SAD PF07973.9 CEP14977.1 - 0.48 10.3 2.8 14 5.6 0.1 3.0 2 1 1 3 3 3 0 Threonyl and Alanyl tRNA synthetase second additional domain AMP-binding PF00501.23 CEP14979.1 - 7.5e-55 186.0 0.9 7.9e-24 83.8 0.1 4.8 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 CEP14979.1 - 1.9e-08 34.8 9.9 1.1e-07 32.4 6.5 2.5 1 1 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 CEP14979.1 - 0.02 14.6 0.1 0.054 13.3 0.1 1.7 1 0 0 1 1 1 0 Gas vesicle protein G Acetyltransf_1 PF00583.19 CEP14980.1 - 1.6e-11 44.0 0.0 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP14980.1 - 3.5e-10 39.8 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP14980.1 - 0.00013 21.7 0.0 0.0003 20.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEP14980.1 - 0.00019 21.3 0.0 0.00046 20.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP14980.1 - 0.0046 16.6 0.0 0.035 13.8 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CEP14980.1 - 0.018 15.1 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEP14980.1 - 0.018 14.9 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 CEP14980.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Cupin_8 PF13621.1 CEP14981.1 - 2.7e-71 239.9 0.1 3.3e-71 239.7 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CEP14981.1 - 0.0084 16.3 0.2 0.27 11.5 0.0 2.7 3 0 0 3 3 3 1 JmjC domain, hydroxylase GPI PF06560.6 CEP14981.1 - 0.029 13.3 0.2 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Cupin_4 PF08007.7 CEP14981.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Rgp1 PF08737.5 CEP14982.1 - 2e-80 270.9 2.3 2e-80 270.9 1.6 2.3 2 1 0 2 2 2 1 Rgp1 Arrestin_C PF02752.17 CEP14982.1 - 0.00017 21.7 0.2 0.23 11.5 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain TFR_dimer PF04253.10 CEP14982.1 - 0.051 13.1 0.1 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain PEMT PF04191.8 CEP14983.1 - 2.1e-49 166.0 9.8 1.1e-30 105.8 0.3 3.4 4 0 0 4 4 4 2 Phospholipid methyltransferase CALCOCO1 PF07888.6 CEP14983.1 - 0.014 13.7 0.2 0.014 13.7 0.1 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATP-synt_B PF00430.13 CEP14983.1 - 0.041 13.6 1.4 0.084 12.6 1.0 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Sec10 PF07393.6 CEP14983.1 - 0.06 11.5 0.6 0.089 10.9 0.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 ApoLp-III PF07464.6 CEP14983.1 - 0.083 12.9 3.6 0.15 12.0 2.5 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF643 PF04867.7 CEP14983.1 - 0.097 13.0 0.5 0.25 11.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF643) DUF1956 PF09209.6 CEP14983.1 - 0.1 12.5 0.2 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1956) DUF883 PF05957.8 CEP14983.1 - 1 9.8 4.3 0.55 10.6 1.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribophorin_I PF04597.9 CEP14984.1 - 9.6e-111 370.3 8.5 4.4e-110 368.1 5.9 1.9 1 1 0 1 1 1 1 Ribophorin I VIT1 PF01988.14 CEP14984.1 - 8.2e-70 234.6 0.1 8.2e-70 234.6 0.1 2.1 3 0 0 3 3 3 1 VIT family Amino_oxidase PF01593.19 CEP14985.1 - 2.1e-15 56.7 0.0 8.5e-07 28.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEP14985.1 - 8.2e-10 38.5 0.1 2.6e-09 36.9 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEP14985.1 - 3.6e-07 29.4 1.0 5.8e-06 25.4 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CEP14985.1 - 0.00022 20.3 0.1 0.00068 18.7 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 CEP14985.1 - 0.00072 19.6 0.1 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP14985.1 - 0.00096 18.9 0.1 0.22 11.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEP14985.1 - 0.0011 18.9 0.3 0.04 13.7 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP14985.1 - 0.0011 19.2 0.9 0.28 11.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEP14985.1 - 0.02 13.3 0.3 1.2 7.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 CEP14985.1 - 0.068 11.7 0.1 0.1 11.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase RNA_pol_L_2 PF13656.1 CEP14985.1 - 0.079 12.4 0.0 7.4 6.0 0.0 3.0 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain FAD_binding_2 PF00890.19 CEP14985.1 - 0.092 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Arrestin_N PF00339.24 CEP14986.1 - 3.2e-17 62.7 0.1 8.8e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP14986.1 - 7.9e-17 61.6 0.4 1.4e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 CEP14986.1 - 0.0053 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like SPT6_acidic PF14632.1 CEP14986.1 - 0.019 15.1 0.1 0.036 14.2 0.1 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Ank_5 PF13857.1 CEP14988.1 - 2.7e-08 33.7 0.0 0.0032 17.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP14988.1 - 8e-08 32.6 0.1 0.00061 20.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CEP14988.1 - 9.4e-08 31.4 0.0 2.7e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 CEP14988.1 - 6.9e-07 29.5 0.0 2.6e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CEP14988.1 - 0.00017 21.4 0.0 0.0095 16.0 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeat YL1_C PF08265.6 CEP14989.1 - 4.8e-18 64.4 0.4 9.1e-18 63.5 0.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain AAA PF00004.24 CEP14990.1 - 1.4e-41 141.7 0.0 2.6e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CEP14990.1 - 4.3e-06 26.7 0.0 9.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CEP14990.1 - 7.7e-06 26.0 0.1 0.00093 19.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CEP14990.1 - 2.1e-05 23.5 0.0 3.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CEP14990.1 - 4.5e-05 23.2 0.3 0.00051 19.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP14990.1 - 0.00021 21.3 0.0 0.0014 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CEP14990.1 - 0.00068 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CEP14990.1 - 0.001 18.9 0.0 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CEP14990.1 - 0.0039 16.8 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEP14990.1 - 0.0041 17.9 0.4 0.011 16.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CEP14990.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP14990.1 - 0.008 15.9 0.4 0.017 14.8 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 CEP14990.1 - 0.012 14.4 0.0 0.071 11.9 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 CEP14990.1 - 0.012 15.8 0.2 0.035 14.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 CEP14990.1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 CEP14990.1 - 0.017 14.2 0.6 0.23 10.5 0.1 2.6 2 1 1 3 3 3 0 KaiC Zeta_toxin PF06414.7 CEP14990.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CEP14990.1 - 0.021 14.7 2.2 0.078 12.9 0.0 2.7 4 0 0 4 4 2 0 AAA domain TIP49 PF06068.8 CEP14990.1 - 0.039 12.6 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 CEP14990.1 - 0.041 13.5 0.1 0.45 10.1 0.1 2.2 1 1 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 CEP14990.1 - 0.074 12.4 1.0 2.3 7.5 0.2 2.5 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.4 CEP14990.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 CEP14990.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CEP14990.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CEP14990.1 - 0.13 11.8 0.2 0.38 10.3 0.2 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CEP14990.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TatD_DNase PF01026.16 CEP14991.1 - 2.7e-53 180.7 0.0 3.3e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CEP14991.1 - 0.14 11.7 0.0 0.46 10.0 0.0 2.0 1 1 0 1 1 1 0 Amidohydrolase Prefoldin PF02996.12 CEP14992.1 - 7.9e-20 70.6 0.9 8.7e-20 70.5 0.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CEP14992.1 - 0.01 15.5 0.4 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF1951 PF09188.5 CEP14992.1 - 0.11 12.4 2.2 0.13 12.1 0.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1951) GnsAB PF08178.6 CEP14992.1 - 2.9 7.6 5.6 3.6 7.3 0.2 2.9 2 2 0 2 2 2 0 GnsA/GnsB family DUF2781 PF10914.3 CEP14993.1 - 3.3e-34 117.8 12.6 4e-34 117.5 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) EBP PF05241.7 CEP14993.1 - 0.025 13.5 1.2 0.04 12.9 0.6 1.4 1 1 0 1 1 1 0 Emopamil binding protein DUF1626 PF07788.6 CEP14993.1 - 0.14 11.9 0.2 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1626) Polysacc_deac_1 PF01522.16 CEP14994.1 - 5e-10 39.0 0.5 1.1e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DEAD PF00270.24 CEP14995.1 - 3.1e-47 160.2 0.0 1.1e-46 158.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP14995.1 - 6.4e-26 90.0 0.0 6.4e-26 90.0 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP14995.1 - 0.0013 18.6 0.0 0.0043 16.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CEP14995.1 - 0.22 11.4 1.9 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain GRP PF07172.6 CEP14995.1 - 1.8 9.0 15.0 4.7 7.7 10.4 1.7 1 0 0 1 1 1 0 Glycine rich protein family DUF3484 PF11983.3 CEP14995.1 - 9.7 7.1 8.9 48 4.8 1.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3484) MARVEL PF01284.18 CEP14996.1 - 1.9e-13 50.4 11.0 2.8e-13 49.9 7.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.7 CEP14996.1 - 6.2e-05 22.5 6.6 0.00033 20.2 4.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF588) NSP2_assoc PF14758.1 CEP14996.1 - 0.08 13.0 0.1 0.18 11.8 0.1 1.4 1 1 1 2 2 2 0 Non-essential region of nsp2 of arterivirus polyprotein Ni_hydr_CYTB PF01292.15 CEP14996.1 - 0.62 9.4 7.8 0.085 12.2 0.5 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF202 PF02656.10 CEP14996.1 - 5.8 7.2 6.6 0.93 9.7 0.6 2.5 1 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF2408 PF10303.4 CEP14997.1 - 3.1e-07 30.5 0.2 3.4e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) AcylCoA_dehyd_C PF12186.3 CEP14997.1 - 0.013 15.3 0.1 1.8 8.4 0.0 2.4 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal CZB PF13682.1 CEP14997.1 - 0.048 13.8 0.0 3.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain Plasmid_killer PF05015.8 CEP14997.1 - 0.087 12.9 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Plasmid maintenance system killer protein PPR_2 PF13041.1 CEP14998.1 - 2.3e-51 171.5 7.6 3.2e-14 52.6 0.0 8.3 3 2 5 8 8 8 6 PPR repeat family PPR_3 PF13812.1 CEP14998.1 - 2.2e-37 124.1 12.7 5.9e-05 23.0 0.0 10.5 11 0 0 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.15 CEP14998.1 - 5.8e-33 110.5 14.7 5.1e-06 26.1 0.0 10.1 10 1 0 10 10 10 5 PPR repeat PPR_1 PF12854.2 CEP14998.1 - 6.4e-33 111.9 4.2 3.9e-06 26.2 0.0 7.9 8 1 0 8 8 8 5 PPR repeat ATP13 PF12921.2 CEP14998.1 - 6.4e-06 25.5 7.4 0.12 11.7 0.0 4.9 4 1 0 5 5 5 2 Mitochondrial ATPase expression TPR_19 PF14559.1 CEP14998.1 - 4e-05 23.8 1.8 4.4 7.7 0.0 5.0 3 2 3 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CEP14998.1 - 0.0011 19.1 2.7 4.7 7.4 0.0 4.5 2 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CEP14998.1 - 0.059 13.1 0.0 12 5.9 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGAP PF00620.22 CEP14998.1 - 0.3 10.6 2.9 4.4 6.8 0.5 2.8 3 0 0 3 3 3 0 RhoGAP domain Ribosomal_L11 PF00298.14 CEP15000.1 - 2e-27 95.1 1.0 2e-27 95.1 0.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CEP15000.1 - 1e-25 88.9 0.1 1.6e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.20 CEP15002.1 - 1.5e-55 188.1 0.0 2.6e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15002.1 - 6.8e-26 90.8 0.0 1.1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15002.1 - 0.042 12.8 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 CEP15002.1 - 0.046 12.7 0.1 0.082 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM92 PF06730.6 CEP15003.1 - 0.012 15.0 4.8 0.02 14.2 2.8 1.7 1 1 1 2 2 2 0 FAM92 protein Helicase_RecD PF05127.9 CEP15003.1 - 0.018 14.6 1.1 0.04 13.5 0.1 2.0 2 1 1 3 3 3 0 Helicase Oxidored-like PF09791.4 CEP15003.1 - 0.029 13.8 0.6 0.073 12.5 0.4 1.7 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal Tox-GHH2 PF15635.1 CEP15003.1 - 0.11 12.8 2.2 0.3 11.4 1.5 1.7 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 CLP_protease PF00574.18 CEP15003.1 - 0.16 11.6 6.4 0.1 12.2 0.4 2.6 2 1 1 3 3 3 0 Clp protease Phage_Integr_2 PF13009.1 CEP15003.1 - 0.17 10.7 8.7 0.26 10.2 5.8 1.4 1 1 0 1 1 1 0 Putative phage integrase LMBR1 PF04791.11 CEP15003.1 - 1.3 7.5 5.4 1.4 7.4 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Arc_PepC_II PF06847.6 CEP15003.1 - 1.9 8.9 4.7 2.7 8.4 0.3 2.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II PRP1_N PF06424.7 CEP15003.1 - 3.2 8.0 13.4 2 8.7 2.0 2.3 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal DUF1762 PF08574.5 CEP15004.1 - 4.6e-11 42.9 19.5 4.6e-11 42.9 13.5 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1762) Kelch_3 PF13415.1 CEP15005.1 - 2.9e-49 164.2 17.9 8.4e-12 44.9 0.1 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP15005.1 - 1.8e-47 158.8 12.5 1.4e-09 37.5 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP15005.1 - 2.6e-39 132.5 14.1 1.1e-07 31.6 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 CEP15005.1 - 6.9e-39 131.1 8.4 9.3e-07 28.2 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CEP15005.1 - 5.6e-35 118.0 15.6 3e-06 27.1 0.0 6.6 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 CEP15005.1 - 5.9e-32 108.2 7.5 1.6e-05 24.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Zip PF02535.17 CEP15005.1 - 0.044 12.7 0.9 0.06 12.3 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 CEP15005.1 - 0.79 8.8 4.9 1.2 8.2 3.4 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Zein-binding PF04576.10 CEP15008.1 - 0.073 13.1 0.2 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Zein-binding MOR2-PAG1_N PF14222.1 CEP15009.1 - 0.045 12.4 0.1 0.049 12.3 0.1 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Sugar_tr PF00083.19 CEP15010.1 - 5.5e-90 302.1 16.7 1.7e-89 300.5 11.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP15010.1 - 1.8e-28 99.2 46.0 8.3e-27 93.8 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BLVR PF06375.6 CEP15011.1 - 0.03 14.1 4.9 0.086 12.6 3.4 1.8 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SecG PF03840.9 CEP15011.1 - 0.16 11.7 0.7 20 4.9 0.0 2.6 2 0 0 2 2 2 0 Preprotein translocase SecG subunit SR-25 PF10500.4 CEP15012.1 - 3.1e-06 26.8 1.0 4.1e-06 26.4 0.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BSP_II PF05432.6 CEP15012.1 - 0.00045 19.5 6.6 0.00059 19.2 4.6 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 CEP15012.1 - 0.0027 15.8 4.2 0.003 15.6 2.9 1.1 1 0 0 1 1 1 1 CDC45-like protein PBP1_TM PF14812.1 CEP15012.1 - 0.012 15.9 2.9 0.021 15.1 2.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2201_N PF13203.1 CEP15012.1 - 0.014 14.5 0.5 0.02 14.1 0.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3449 PF11931.3 CEP15012.1 - 0.019 14.4 0.8 0.028 13.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) TLP-20 PF06088.6 CEP15012.1 - 0.024 14.3 1.6 0.03 14.0 1.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.8 CEP15012.1 - 0.08 12.5 7.2 0.14 11.7 5.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 CEP15012.1 - 0.083 10.7 10.0 0.1 10.4 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 CEP15012.1 - 0.23 10.5 9.9 0.3 10.1 6.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GOLD_2 PF13897.1 CEP15012.1 - 2.6 8.2 5.2 5 7.3 3.6 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking UPF0560 PF10577.4 CEP15012.1 - 7.1 4.7 8.4 9.1 4.3 5.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2457 PF10446.4 CEP15012.1 - 8.5 4.9 16.7 12 4.4 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PIGA PF08288.7 CEP15013.1 - 3.5e-45 152.2 0.5 7.8e-45 151.1 0.4 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CEP15013.1 - 2.2e-25 89.0 0.0 3.9e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CEP15013.1 - 6.4e-14 52.0 0.4 1.2e-13 51.2 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CEP15013.1 - 1.8e-13 50.9 0.0 3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CEP15013.1 - 8.4e-11 42.1 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CEP15013.1 - 5.3e-05 23.0 0.3 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like CTP_transf_2 PF01467.21 CEP15014.1 - 8.4e-22 77.9 0.0 1.5e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Glu-tRNAGln PF02686.10 CEP15015.1 - 0.047 13.4 0.1 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit SCF PF02404.10 CEP15015.1 - 0.052 12.7 0.1 0.06 12.5 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor Arc_PepC PF06819.6 CEP15015.1 - 0.1 12.5 0.1 3.6 7.5 0.0 2.7 1 1 2 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain Uteroglobin PF01099.12 CEP15015.1 - 0.17 11.7 2.8 7.2 6.4 0.0 3.2 2 1 1 3 3 3 0 Uteroglobin family ASXH PF13919.1 CEP15016.1 - 2.8e-22 78.9 3.0 1.9e-21 76.2 0.3 2.7 2 0 0 2 2 2 1 Asx homology domain RhoGAP PF00620.22 CEP15017.1 - 1e-48 164.7 0.0 4.6e-48 162.6 0.0 2.2 1 0 0 1 1 1 1 RhoGAP domain Pribosyltran_N PF13793.1 CEP15017.1 - 1.4e-40 137.6 0.3 6.6e-40 135.4 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CEP15017.1 - 1.1e-32 113.3 3.8 1.1e-32 113.3 2.6 3.8 3 1 0 3 3 3 1 Phosphoribosyl synthetase-associated domain RasGEF PF00617.14 CEP15017.1 - 1.4e-22 80.3 1.1 3.5e-14 52.9 0.0 4.4 3 1 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 CEP15017.1 - 1.1e-20 73.7 12.9 3.3e-13 49.6 1.8 5.1 5 1 0 5 5 5 2 RasGEF N-terminal motif PH_9 PF15410.1 CEP15017.1 - 5.5e-19 68.4 4.0 3.2e-13 49.8 0.0 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain PH PF00169.24 CEP15017.1 - 2.1e-14 53.5 2.2 1.7e-05 24.9 0.1 3.7 3 0 0 3 3 3 2 PH domain Pribosyltran PF00156.22 CEP15017.1 - 0.0014 18.3 0.4 0.02 14.5 0.2 3.1 2 1 0 2 2 2 1 Phosphoribosyl transferase domain HSF_DNA-bind PF00447.12 CEP15018.1 - 9.2e-36 122.1 2.6 2.2e-35 120.9 1.8 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_L1 PF00687.16 CEP15018.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family Cortex-I_coil PF09304.5 CEP15018.1 - 0.088 12.8 1.9 0.15 12.1 1.3 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DDE_Tnp_1_7 PF13843.1 CEP15019.1 - 8.3e-14 51.3 0.0 9.2e-10 38.0 0.0 2.4 1 1 1 2 2 2 2 Transposase IS4 DUF3813 PF12758.2 CEP15019.1 - 0.033 14.3 0.1 0.83 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Aldedh PF00171.17 CEP15020.1 - 7.7e-67 225.6 0.0 9.4e-44 149.5 0.0 3.0 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 CEP15020.1 - 0.027 13.1 0.0 0.37 9.4 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Far-17a_AIG1 PF04750.9 CEP15021.1 - 6.1e-41 139.8 9.9 6.9e-41 139.6 6.9 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3082 PF11282.3 CEP15021.1 - 0.4 10.7 2.8 9.6 6.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3082) 2Fe-2S_thioredx PF01257.14 CEP15022.1 - 1.5e-59 199.7 0.1 2e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DAGK_cat PF00781.19 CEP15023.1 - 8.8e-18 63.9 0.0 2.4e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 CEP15023.1 - 0.0098 14.6 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase ABC_tran PF00005.22 CEP15025.1 - 8.1e-36 123.3 0.0 1.9e-35 122.1 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 CEP15025.1 - 1.7e-26 93.2 11.7 2.5e-23 82.8 3.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CEP15025.1 - 2.3e-07 30.2 1.1 1.8e-05 24.1 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEP15025.1 - 5.1e-06 26.6 0.0 0.018 15.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 CEP15025.1 - 8.1e-05 23.4 0.0 0.0002 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP15025.1 - 0.00025 21.2 0.1 0.0027 17.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CEP15025.1 - 0.00031 20.2 0.0 0.054 12.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain ABC_membrane_2 PF06472.10 CEP15025.1 - 0.00044 19.4 0.2 0.00083 18.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 APS_kinase PF01583.15 CEP15025.1 - 0.00064 19.4 0.0 0.0022 17.6 0.0 1.9 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.1 CEP15025.1 - 0.0016 17.8 0.7 0.0082 15.6 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CEP15025.1 - 0.0018 18.6 0.0 0.0051 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP15025.1 - 0.0025 17.8 1.1 0.0098 15.8 0.3 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CEP15025.1 - 0.0046 17.1 1.0 0.14 12.3 0.7 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 CEP15025.1 - 0.0061 15.1 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 CEP15025.1 - 0.0067 15.5 0.0 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin DEAD PF00270.24 CEP15025.1 - 0.009 15.5 0.4 0.11 12.0 0.3 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 CEP15025.1 - 0.014 14.8 0.1 0.31 10.4 0.0 2.5 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 CEP15025.1 - 0.015 15.1 0.0 0.056 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CEP15025.1 - 0.023 13.8 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 CEP15025.1 - 0.028 14.1 0.0 0.43 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 CEP15025.1 - 0.032 14.1 0.5 0.22 11.4 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CEP15025.1 - 0.055 12.8 1.7 2.8 7.2 0.2 2.6 1 1 2 3 3 3 0 AAA-like domain AAA_30 PF13604.1 CEP15025.1 - 0.059 12.9 0.2 4.7 6.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CEP15025.1 - 0.12 12.3 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DDE_3 PF13358.1 CEP15026.1 - 7.7e-19 67.8 0.0 2.2e-18 66.3 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP15026.1 - 0.00056 19.1 0.1 0.00088 18.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MarR_2 PF12802.2 CEP15026.1 - 0.034 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.1 CEP15026.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Peptidase_S30 PF01577.11 CEP15026.1 - 0.22 10.9 2.6 0.14 11.5 0.5 1.6 2 0 0 2 2 2 0 Potyvirus P1 protease WD40 PF00400.27 CEP15027.1 - 6.3e-15 54.3 0.3 0.45 10.4 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEP15027.1 - 0.049 12.3 1.4 1.8 7.1 0.6 2.9 2 1 0 2 2 2 0 Nup133 N terminal like PH PF00169.24 CEP15028.1 - 1.1e-05 25.5 0.3 0.00021 21.4 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 CEP15028.1 - 0.00022 21.3 0.0 0.00022 21.3 0.0 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain CENP-B_dimeris PF09026.5 CEP15028.1 - 0.21 11.8 15.4 1.9 8.7 4.1 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain OrfB_Zn_ribbon PF07282.6 CEP15029.1 - 0.076 12.6 0.6 0.32 10.6 0.3 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Homeobox PF00046.24 CEP15030.1 - 3.4e-18 65.0 4.7 7e-18 64.0 3.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP15030.1 - 0.074 12.7 0.4 0.17 11.5 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF791 PF05631.9 CEP15030.1 - 0.077 11.6 0.1 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF791) PCI PF01399.22 CEP15031.1 - 4.5e-11 42.9 1.0 3.3e-10 40.1 0.1 2.8 2 0 0 2 2 2 1 PCI domain Lipl32 PF12103.3 CEP15031.1 - 0.88 9.0 5.1 0.45 9.9 0.9 2.3 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Syntaxin-6_N PF09177.6 CEP15032.1 - 3e-24 85.2 2.2 3e-24 85.2 1.5 1.8 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 CEP15032.1 - 3.6e-13 48.9 6.5 1.4e-12 47.0 1.9 2.6 2 0 0 2 2 2 1 SNARE domain RasGAP_C PF03836.10 CEP15032.1 - 0.0005 19.7 0.7 0.0005 19.7 0.5 2.1 1 1 1 2 2 2 1 RasGAP C-terminus CENP-Q PF13094.1 CEP15032.1 - 0.024 14.6 10.1 0.17 11.9 5.7 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FliJ PF02050.11 CEP15032.1 - 0.053 13.5 11.1 0.58 10.2 1.6 2.7 2 1 0 2 2 2 0 Flagellar FliJ protein NPV_P10 PF05531.7 CEP15032.1 - 0.061 13.5 3.6 0.15 12.3 0.3 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 CEP15032.1 - 0.47 9.9 7.3 0.066 12.7 1.5 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Allexi_40kDa PF05549.6 CEP15032.1 - 0.58 9.4 4.0 0.5 9.6 1.3 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF745 PF05335.8 CEP15032.1 - 1.2 8.6 8.5 1.6 8.1 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF3571 PF12095.3 CEP15032.1 - 3 8.1 5.3 27 5.0 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) DUF4164 PF13747.1 CEP15032.1 - 3.6 7.7 7.4 30 4.8 2.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.7 CEP15032.1 - 3.7 7.2 9.7 0.98 9.1 2.9 2.4 2 1 0 2 2 2 0 Laminin Domain II Ribonuclease_T2 PF00445.13 CEP15033.1 - 2.9e-30 105.2 2.5 4.1e-30 104.8 0.0 2.4 3 0 0 3 3 3 1 Ribonuclease T2 family HAD PF12710.2 CEP15033.1 - 2e-19 70.5 0.4 2.4e-18 66.9 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP15033.1 - 5.9e-15 56.2 0.0 2.4e-13 51.0 0.0 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEP15033.1 - 1.9e-13 49.9 0.0 3.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CEP15033.1 - 3.6e-13 49.2 0.1 2.6e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEP15033.1 - 0.012 15.2 0.1 0.012 15.2 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase TFIID-31kDa PF02291.10 CEP15034.1 - 3.1e-49 166.0 0.0 3.7e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 CEP15034.1 - 1.4e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 CEP15034.1 - 3.1e-05 24.0 0.0 4.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_30kDa PF03540.8 CEP15034.1 - 0.00096 18.9 0.4 0.0017 18.1 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit CENP-S PF15630.1 CEP15034.1 - 0.0016 18.5 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CTP_transf_2 PF01467.21 CEP15035.1 - 1.1e-35 122.9 1.1 1.4e-19 70.7 0.0 3.0 2 1 1 3 3 3 2 Cytidylyltransferase FAD_syn PF06574.7 CEP15035.1 - 0.00022 20.9 0.3 0.6 9.7 0.0 2.6 2 1 0 2 2 2 2 FAD synthetase ScdA_N PF04405.9 CEP15035.1 - 0.026 13.9 0.1 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) CoA_binding_3 PF13727.1 CEP15035.1 - 0.032 14.0 0.0 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 CoA-binding domain F-box-like PF12937.2 CEP15037.1 - 1.6e-09 37.2 0.0 8.3e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP15037.1 - 0.00046 19.7 0.0 0.0018 17.8 0.0 2.1 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 CEP15037.1 - 2.3 8.2 7.4 1.8 8.6 0.1 3.7 4 0 0 4 4 4 0 PRANC domain Pkinase PF00069.20 CEP15038.1 - 2.3e-68 230.1 0.0 5.7e-68 228.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15038.1 - 1.9e-53 181.1 0.0 3.1e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15038.1 - 7.4e-06 25.1 0.0 0.0011 17.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like C1_1 PF00130.17 CEP15038.1 - 0.00047 19.8 9.5 0.00047 19.8 6.6 2.1 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.17 CEP15038.1 - 0.0005 19.4 0.1 0.0019 17.6 0.0 1.9 1 1 0 1 1 1 1 RIO1 family Ras PF00071.17 CEP15039.1 - 5.7e-51 172.1 0.0 6.7e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP15039.1 - 1.6e-13 51.2 0.0 3e-13 50.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP15039.1 - 2.7e-08 33.2 0.0 3.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP15039.1 - 8e-06 25.4 0.0 1.5e-05 24.4 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 CEP15039.1 - 0.0031 16.9 0.3 0.013 14.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CEP15039.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP15039.1 - 0.016 14.5 0.2 0.13 11.5 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 CEP15039.1 - 0.032 13.4 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 CEP15039.1 - 0.073 12.0 0.1 2 7.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CEP15039.1 - 0.14 12.3 0.9 5.5 7.1 0.1 2.8 1 1 1 2 2 2 0 AAA domain WD40 PF00400.27 CEP15040.1 - 4.9e-50 165.7 13.7 5.7e-10 38.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF3347 PF11827.3 CEP15040.1 - 0.1 12.5 2.4 0.17 11.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Nol1_Nop2_Fmu_2 PF13636.1 CEP15040.1 - 0.1 12.6 0.1 21 5.2 0.0 3.2 2 1 1 3 3 3 0 pre-rRNA processing and ribosome biogenesis AP-5_subunit_s1 PF15001.1 CEP15040.1 - 0.12 12.3 0.5 0.21 11.5 0.4 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Nup160 PF11715.3 CEP15040.1 - 0.15 10.1 4.5 2.7 6.0 0.2 3.8 2 1 3 5 5 5 0 Nucleoporin Nup120/160 CN_hydrolase PF00795.17 CEP15041.1 - 9.9e-12 44.5 0.0 1.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CHASE4 PF05228.8 CEP15041.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 CHASE4 domain SAP PF02037.22 CEP15042.1 - 7.6e-13 47.6 1.6 7.6e-13 47.6 1.1 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 CEP15042.1 - 0.019 14.4 1.8 0.066 12.7 1.2 2.0 1 0 0 1 1 1 0 HeH/LEM domain IncA PF04156.9 CEP15042.1 - 0.065 12.8 3.7 0.11 12.0 2.5 1.3 1 0 0 1 1 1 0 IncA protein DUF3508 PF12018.3 CEP15042.1 - 0.083 11.8 0.5 0.15 11.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) DUF4375 PF14300.1 CEP15042.1 - 0.15 12.0 4.5 0.07 13.1 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF848 PF05852.6 CEP15042.1 - 0.23 11.2 6.3 0.59 9.9 4.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Mycoplasma_p37 PF06646.6 CEP15042.1 - 0.33 9.9 3.1 0.63 9.0 1.6 1.7 2 0 0 2 2 2 0 High affinity transport system protein p37 DHOase PF12890.2 CEP15042.1 - 0.72 9.5 4.7 13 5.4 0.1 2.6 1 1 1 2 2 2 0 Dihydro-orotase-like Kelch_4 PF13418.1 CEP15044.1 - 2.1e-21 75.4 14.9 2.1e-05 24.2 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP15044.1 - 2.4e-17 62.2 13.9 0.00015 21.7 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 CEP15044.1 - 1.3e-14 53.9 19.8 0.0002 21.4 0.1 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP15044.1 - 3.8e-14 51.7 4.4 0.0028 17.3 0.0 6.7 7 0 0 7 7 7 2 Kelch motif Kelch_5 PF13854.1 CEP15044.1 - 3.6e-13 49.1 15.0 0.025 14.5 0.0 6.8 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CEP15044.1 - 3.1e-09 36.2 4.7 0.0022 17.5 0.1 5.2 5 0 0 5 5 5 2 Kelch motif VSP PF03302.8 CEP15044.1 - 6.3 5.3 4.6 2.7 6.5 1.4 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein CTP_transf_2 PF01467.21 CEP15045.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase DUF4440 PF14534.1 CEP15045.1 - 0.028 14.6 0.1 0.087 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Peptidase_C14 PF00656.17 CEP15046.1 - 1.2e-51 175.8 0.1 3.1e-51 174.4 0.1 1.7 1 0 0 1 1 1 1 Caspase domain Proteasome PF00227.21 CEP15046.1 - 1.5e-36 125.5 0.2 3e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit Snf7 PF03357.16 CEP15046.1 - 2e-25 89.1 6.9 2e-25 89.1 4.8 2.3 2 0 0 2 2 2 1 Snf7 Brix PF04427.13 CEP15047.1 - 5.5e-50 169.6 0.2 7.2e-50 169.3 0.1 1.1 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.20 CEP15047.1 - 0.05 13.5 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Bromodomain MgsA_C PF12002.3 CEP15047.1 - 0.083 12.5 0.3 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal CTDII PF01556.13 CEP15048.1 - 1.4e-28 98.5 1.4 1.9e-23 82.1 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 CEP15048.1 - 1.4e-27 95.2 3.3 2.4e-27 94.4 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CEP15048.1 - 1.8e-13 50.3 21.3 3.3e-13 49.4 14.8 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CEP15048.1 - 0.0012 18.5 7.7 0.047 13.3 1.1 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Snurportin1 PF11538.3 CEP15049.1 - 0.0047 16.6 5.9 0.011 15.5 4.1 1.6 1 0 0 1 1 1 1 Snurportin1 mRNA_cap_enzyme PF01331.14 CEP15049.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain IBB PF01749.15 CEP15049.1 - 0.54 10.4 10.3 0.19 11.9 4.8 1.9 1 1 1 2 2 2 0 Importin beta binding domain Pex16 PF08610.5 CEP15049.1 - 1.3 7.9 4.0 1.9 7.3 2.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) adh_short PF00106.20 CEP15050.1 - 1.3e-14 54.4 0.0 2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP15050.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP15050.1 - 5.9e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CEP15050.1 - 0.0025 16.5 0.2 0.0072 15.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_11 PF13414.1 CEP15051.1 - 8.6e-20 70.1 11.0 5.8e-09 35.4 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CEP15051.1 - 1e-17 62.8 5.3 0.00076 18.9 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CEP15051.1 - 2.4e-14 52.0 8.8 0.001 18.8 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CEP15051.1 - 4.1e-11 42.4 9.2 0.012 16.1 0.9 5.0 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CEP15051.1 - 1.1e-10 40.8 3.1 0.003 17.6 0.1 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEP15051.1 - 1.6e-09 37.9 7.4 3.9e-05 23.9 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 CEP15051.1 - 1.1e-07 31.7 4.7 0.016 15.3 0.0 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP15051.1 - 1.6e-07 31.8 12.4 0.0004 20.9 0.0 4.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEP15051.1 - 3.2e-07 29.6 1.6 0.78 9.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP15051.1 - 2.5e-06 27.3 14.0 0.0027 17.6 0.9 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEP15051.1 - 1.2e-05 24.7 5.4 0.17 11.7 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP15051.1 - 9.5e-05 22.4 4.4 0.00033 20.7 0.4 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CEP15051.1 - 0.001 18.8 6.9 1.1 9.1 0.1 3.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_4 PF07721.9 CEP15051.1 - 0.011 16.0 0.1 0.044 14.2 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP15051.1 - 0.13 12.7 0.7 7.1 7.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEP15051.1 - 3.4 7.7 9.6 1.3 9.0 0.8 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat ERCC4 PF02732.10 CEP15052.1 - 1.4e-08 34.6 0.2 3.7e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 ERCC4 domain CUE PF02845.11 CEP15052.1 - 0.029 13.8 0.0 0.079 12.4 0.0 1.8 1 0 0 1 1 1 0 CUE domain V_ATPase_I PF01496.14 CEP15052.1 - 1.5 6.5 7.1 2.1 6.0 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KIP1 PF07765.7 CEP15057.1 - 0.06 13.2 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 KIP1-like protein DUF4460 PF14687.1 CEP15058.1 - 5.8e-09 35.7 0.2 1.1e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DnaJ PF00226.26 CEP15058.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain Pox_C7_F8A PF03287.9 CEP15058.1 - 0.12 12.0 0.1 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Poxvirus C7/F8A protein NAD_binding_10 PF13460.1 CEP15059.1 - 2.2e-06 27.8 0.1 4.4e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CEP15059.1 - 0.00091 18.2 0.0 0.0097 14.8 0.0 1.9 1 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 CEP15059.1 - 0.0047 16.8 0.3 0.015 15.2 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CEP15059.1 - 0.0053 16.2 0.0 0.055 12.8 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Mito_carr PF00153.22 CEP15060.1 - 1e-44 150.1 9.8 1e-19 70.0 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_18 PF00704.23 CEP15061.1 - 1e-82 278.3 5.0 1.3e-82 278.0 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 CEP15061.1 - 0.00016 21.4 2.3 0.00016 21.4 1.6 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) Toxin_20 PF08089.6 CEP15061.1 - 0.036 13.9 0.7 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 Huwentoxin-II family DUF4237 PF14021.1 CEP15061.1 - 0.041 14.1 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4237) Zn_clus PF00172.13 CEP15062.1 - 3.6e-09 36.3 7.1 8.5e-09 35.1 4.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TLD PF07534.11 CEP15063.1 - 9.8e-26 90.4 0.7 2e-25 89.4 0.5 1.5 1 0 0 1 1 1 1 TLD WBS_methylT PF12589.3 CEP15063.1 - 0.17 12.3 2.9 0.2 12.1 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Cyclophil_like PF04126.8 CEP15066.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like rve PF00665.21 CEP15068.1 - 8.5e-14 51.6 0.0 2.1e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP15068.1 - 1.3e-08 34.3 1.3 3.2e-08 33.1 0.9 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ErmC PF06308.6 CEP15071.1 - 0.021 14.8 5.2 2 8.5 0.0 2.8 3 0 0 3 3 3 0 23S rRNA methylase leader peptide (ErmC) Phage_integrase PF00589.17 CEP15071.1 - 0.025 14.2 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family NADHdh-2_N PF12155.3 CEP15074.1 - 0.039 14.1 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal PH PF00169.24 CEP15075.1 - 9.5e-10 38.6 13.8 2.8e-05 24.2 0.9 4.5 3 1 0 3 3 3 2 PH domain PH_11 PF15413.1 CEP15075.1 - 0.02 15.1 0.1 5.6 7.2 0.0 3.6 2 1 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.1 CEP15075.1 - 0.71 10.0 13.1 19 5.4 0.1 4.9 5 0 0 5 5 5 0 Pleckstrin homology domain CSD PF00313.17 CEP15076.1 - 3.4e-10 39.5 0.0 0.00017 21.2 0.0 2.3 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain SMN PF06003.7 CEP15076.1 - 0.13 11.3 1.2 0.23 10.5 0.8 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DASH_Duo1 PF08651.5 CEP15077.1 - 8.3e-07 28.5 3.1 0.00038 19.9 0.2 2.2 2 0 0 2 2 2 2 DASH complex subunit Duo1 DUF948 PF06103.6 CEP15077.1 - 0.00013 21.7 7.3 0.00071 19.3 3.3 2.2 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 CEP15077.1 - 0.00045 19.9 5.3 0.00055 19.7 2.5 1.8 1 1 1 2 2 2 2 Laminin Domain II Herpes_U30 PF04523.8 CEP15077.1 - 0.00095 16.7 1.2 0.0011 16.5 0.9 1.0 1 0 0 1 1 1 1 Herpes virus tegument protein U30 GAS PF13851.1 CEP15077.1 - 0.0011 18.2 2.1 0.0014 17.8 1.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DHC_N1 PF08385.7 CEP15077.1 - 0.0011 17.4 2.6 0.0013 17.2 1.8 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 MCPsignal PF00015.16 CEP15077.1 - 0.0017 17.9 3.5 0.0021 17.6 2.4 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain MAD PF05557.8 CEP15077.1 - 0.002 16.3 2.6 0.0024 16.0 1.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Syntaxin_2 PF14523.1 CEP15077.1 - 0.003 17.5 5.9 0.0077 16.2 1.6 2.1 1 1 1 2 2 2 1 Syntaxin-like protein BLOC1_2 PF10046.4 CEP15077.1 - 0.0062 16.6 6.8 0.015 15.3 4.7 1.8 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 WEMBL PF05701.6 CEP15077.1 - 0.009 14.5 3.4 0.012 14.0 2.4 1.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light IFT57 PF10498.4 CEP15077.1 - 0.0097 14.6 2.4 0.011 14.4 1.7 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 XkdN PF08890.6 CEP15077.1 - 0.012 15.3 1.9 0.014 15.1 1.3 1.2 1 0 0 1 1 1 0 Phage XkdN-like protein DUF4200 PF13863.1 CEP15077.1 - 0.014 15.3 2.7 0.047 13.6 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 CEP15077.1 - 0.015 15.0 6.1 0.057 13.2 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lyase_8_N PF08124.6 CEP15077.1 - 0.017 13.9 2.2 0.022 13.6 1.5 1.0 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain AKNA PF12443.3 CEP15077.1 - 0.018 15.0 0.7 0.44 10.5 0.1 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor Nsp1_C PF05064.8 CEP15077.1 - 0.018 14.6 2.4 0.026 14.1 1.1 1.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region AAA_13 PF13166.1 CEP15077.1 - 0.021 13.2 5.4 0.026 13.0 3.7 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 CEP15077.1 - 0.024 13.9 2.0 0.028 13.6 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1657 PF07870.6 CEP15077.1 - 0.026 14.2 2.0 2.9 7.6 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1657) Syntaxin-6_N PF09177.6 CEP15077.1 - 0.028 14.8 3.8 0.22 11.9 2.5 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HAUS-augmin3 PF14932.1 CEP15077.1 - 0.033 13.3 2.6 0.038 13.1 1.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Nup54 PF13874.1 CEP15077.1 - 0.035 13.7 0.5 0.046 13.3 0.4 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.14 CEP15077.1 - 0.037 11.9 1.9 0.041 11.7 1.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF812 PF05667.6 CEP15077.1 - 0.043 12.3 3.0 0.058 11.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Wx5_PLAF3D7 PF09688.5 CEP15077.1 - 0.048 13.6 3.7 0.45 10.4 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) EntA_Immun PF08951.5 CEP15077.1 - 0.048 13.8 1.1 0.1 12.7 0.1 1.9 1 1 1 2 2 2 0 Enterocin A Immunity ALIX_LYPXL_bnd PF13949.1 CEP15077.1 - 0.049 12.5 2.6 0.15 10.9 1.8 1.7 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Atg14 PF10186.4 CEP15077.1 - 0.063 12.2 0.6 0.069 12.0 0.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4252 PF14060.1 CEP15077.1 - 0.065 12.7 2.4 0.079 12.5 1.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) DUF2730 PF10805.3 CEP15077.1 - 0.067 12.9 2.0 0.25 11.1 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF745 PF05335.8 CEP15077.1 - 0.067 12.7 2.2 0.21 11.1 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) IncA PF04156.9 CEP15077.1 - 0.071 12.6 0.5 0.093 12.3 0.3 1.3 1 0 0 1 1 1 0 IncA protein Phage_GP20 PF06810.6 CEP15077.1 - 0.072 12.5 6.4 0.091 12.1 4.5 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 V-SNARE PF05008.10 CEP15077.1 - 0.076 13.1 1.0 0.28 11.3 0.2 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Anti-adapt_IraP PF10796.4 CEP15077.1 - 0.079 13.3 4.0 0.37 11.2 1.1 2.1 1 1 1 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Cluap1 PF10234.4 CEP15077.1 - 0.089 11.9 3.0 0.12 11.5 2.0 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 Reo_sigmaC PF04582.7 CEP15077.1 - 0.095 11.8 2.4 0.1 11.7 1.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 CEP15077.1 - 0.1 12.6 4.4 0.16 12.0 1.5 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 CEP15077.1 - 0.13 12.4 4.2 1.1 9.4 2.9 2.2 1 1 0 1 1 1 0 Syntaxin SlyX PF04102.7 CEP15077.1 - 0.13 12.6 1.6 4.6 7.7 0.2 2.5 1 1 1 2 2 2 0 SlyX Rsd_AlgQ PF04353.8 CEP15077.1 - 0.16 11.6 2.4 0.19 11.4 1.3 1.4 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Tweety PF04906.8 CEP15077.1 - 0.17 10.2 1.9 0.19 10.1 1.3 1.1 1 0 0 1 1 1 0 Tweety LOH1CR12 PF10158.4 CEP15077.1 - 0.17 11.6 2.4 0.28 10.9 1.6 1.3 1 1 0 1 1 1 0 Tumour suppressor protein Spc7 PF08317.6 CEP15077.1 - 0.18 10.4 5.4 0.3 9.7 3.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1993 PF09351.5 CEP15077.1 - 0.19 11.6 2.0 0.93 9.4 0.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) zf-C4H2 PF10146.4 CEP15077.1 - 0.22 11.5 1.5 0.31 11.0 1.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Fib_alpha PF08702.5 CEP15077.1 - 0.22 11.6 5.8 0.33 11.0 4.0 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.6 CEP15077.1 - 0.26 10.5 2.0 0.3 10.3 1.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein TBPIP PF07106.8 CEP15077.1 - 0.26 10.8 4.6 0.6 9.6 3.2 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 CEP15077.1 - 0.28 10.8 5.0 3.9 7.1 0.9 2.3 1 1 1 2 2 2 0 Prefoldin subunit Baculo_PEP_C PF04513.7 CEP15077.1 - 0.33 10.7 6.9 1.2 8.9 4.8 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 CEP15077.1 - 0.38 10.5 4.4 3.6 7.4 0.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2533 PF10752.4 CEP15077.1 - 0.68 10.2 3.5 0.51 10.6 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2533) NPV_P10 PF05531.7 CEP15077.1 - 1.2 9.3 8.7 4 7.7 2.4 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Lge1 PF11488.3 CEP15077.1 - 1.5 9.0 4.9 18 5.5 3.4 2.1 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 zf-H2C2_2 PF13465.1 CEP15078.1 - 4.4e-09 36.1 17.5 1.1e-05 25.4 2.1 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEP15078.1 - 4.7e-05 23.4 0.6 4.7e-05 23.4 0.4 5.5 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP15078.1 - 0.0022 18.1 31.2 0.0022 18.1 0.1 6.3 6 0 0 6 6 6 2 C2H2-type zinc finger NRDE PF05742.7 CEP15078.1 - 0.16 11.2 3.0 0.32 10.2 2.1 1.4 1 0 0 1 1 1 0 NRDE protein RRM_1 PF00076.17 CEP15079.1 - 1e-06 28.2 0.1 2.1e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP15079.1 - 1e-05 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Med18 PF09637.5 CEP15079.1 - 0.018 14.5 0.6 0.031 13.8 0.4 1.4 1 0 0 1 1 1 0 Med18 protein Prp19 PF08606.6 CEP15079.1 - 0.047 13.4 0.3 0.047 13.4 0.2 2.2 2 0 0 2 2 2 0 Prp19/Pso4-like LZ_Tnp_IS66 PF13007.2 CEP15079.1 - 0.063 13.9 4.8 0.3 11.7 0.0 3.1 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain ATP-synt PF00231.14 CEP15080.1 - 5.4e-69 232.7 6.2 6.2e-69 232.5 4.3 1.0 1 0 0 1 1 1 1 ATP synthase DBR1 PF05011.8 CEP15081.1 - 2.5e-36 124.7 1.2 4.6e-36 123.8 0.8 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CEP15081.1 - 1.4e-12 47.3 3.8 2.3e-12 46.7 2.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP15081.1 - 9.7e-05 22.2 0.0 0.00019 21.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ExbD PF02472.11 CEP15081.1 - 2.1 8.3 6.4 0.45 10.5 0.8 2.3 2 1 0 2 2 2 0 Biopolymer transport protein ExbD/TolR LOH1CR12 PF10158.4 CEP15082.1 - 1.5e-05 24.8 0.4 3.1e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 Tumour suppressor protein Acetyltransf_1 PF00583.19 CEP15083.1 - 1.6e-17 63.3 0.0 2.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP15083.1 - 3.5e-08 33.4 0.0 6.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP15083.1 - 7.7e-08 32.4 0.0 9.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP15083.1 - 4.2e-06 26.9 0.0 5.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP15083.1 - 9.4e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 CEP15083.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 CEP15083.1 - 0.034 13.9 0.0 0.079 12.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEP15083.1 - 0.061 13.1 0.0 0.27 11.1 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SURF6 PF04935.7 CEP15084.1 - 6.9e-31 107.1 47.6 6.9e-31 107.1 33.0 3.0 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 CEP15084.1 - 2.3e-19 69.2 5.0 2.3e-19 69.2 3.4 5.8 4 1 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 DIL PF01843.14 CEP15085.1 - 4.3e-20 71.5 3.6 1.1e-19 70.1 2.5 1.8 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 CEP15085.1 - 3.2e-17 62.6 0.0 6.6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEP15085.1 - 1.4e-13 49.8 0.0 4e-05 23.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CEP15085.1 - 9.8e-11 40.8 0.0 0.0012 18.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CEP15085.1 - 4.5e-10 39.7 0.0 8.9e-05 22.8 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP15085.1 - 1.3e-08 34.8 0.0 5.6e-06 26.4 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEP15086.1 - 1e-31 109.1 0.3 4.5e-17 62.1 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEP15086.1 - 3.1e-30 102.4 0.2 1.5e-06 27.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 CEP15086.1 - 2.1e-29 101.3 0.5 1.9e-07 31.4 0.1 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP15086.1 - 5.2e-26 90.0 0.7 4.9e-09 36.1 0.1 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP15086.1 - 3.4e-22 76.3 4.2 1.8e-05 24.5 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.16 CEP15086.1 - 8.9e-17 60.7 9.1 1.7e-16 59.8 6.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger EF-hand_6 PF13405.1 CEP15087.1 - 2.9e-07 29.8 0.5 8.1e-07 28.4 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CEP15087.1 - 8.9e-07 28.9 1.5 1.9e-06 27.8 1.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CEP15087.1 - 2e-05 23.6 2.2 4.7e-05 22.5 1.5 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CEP15087.1 - 0.00013 21.0 1.0 0.00013 21.0 0.7 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CEP15087.1 - 0.0086 15.6 5.0 0.09 12.4 1.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CEP15087.1 - 0.11 12.4 0.2 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region RRM_1 PF00076.17 CEP15088.1 - 2.8e-27 94.1 0.0 2.8e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 CEP15088.1 - 3.1e-23 79.9 1.2 2.7e-06 26.5 0.0 4.4 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat RRM_6 PF14259.1 CEP15088.1 - 5.1e-20 71.2 0.0 1.3e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP15088.1 - 1.9e-15 56.4 0.0 8.9e-07 28.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP15088.1 - 0.0013 18.5 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 CEP15088.1 - 0.015 14.9 0.1 0.19 11.4 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 Nab6_mRNP_bdg PF10567.4 CEP15088.1 - 0.12 11.2 0.3 0.93 8.4 0.0 2.4 3 0 0 3 3 3 0 RNA-recognition motif Peroxin-13_N PF04088.8 CEP15089.1 - 9.2e-48 162.1 0.1 1.4e-47 161.5 0.1 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 CEP15089.1 - 3e-13 48.9 0.0 5.7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP15089.1 - 1.7e-12 46.7 0.0 3.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP15089.1 - 2e-10 39.9 0.0 4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PMG PF05287.7 CEP15089.1 - 0.011 15.5 2.2 0.017 14.8 1.5 1.3 1 0 0 1 1 1 0 PMG protein Pex2_Pex12 PF04757.9 CEP15089.1 - 0.062 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Ribosomal_S2 PF00318.15 CEP15090.1 - 0.44 9.7 4.1 0.85 8.8 2.6 1.7 1 1 1 2 2 2 0 Ribosomal protein S2 NUDIX PF00293.23 CEP15091.1 - 2.1e-29 101.8 0.0 3.1e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FA_desaturase PF00487.19 CEP15096.1 - 6.2e-56 189.6 24.7 9.7e-56 189.0 17.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CEP15096.1 - 6e-15 54.8 0.0 1.6e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC2_membrane PF01061.19 CEP15097.1 - 1.9e-84 282.0 71.5 5.1e-49 166.3 14.3 3.6 5 0 0 5 5 5 2 ABC-2 type transporter ABC_tran PF00005.22 CEP15097.1 - 8.1e-36 123.3 2.3 2.3e-19 70.0 0.0 3.4 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.7 CEP15097.1 - 1.8e-29 101.4 0.8 1.9e-23 82.0 0.0 3.9 4 1 1 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.1 CEP15097.1 - 1.8e-11 43.9 0.1 4.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CEP15097.1 - 2.8e-09 36.5 14.4 2.8e-09 36.5 10.0 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CEP15097.1 - 3.9e-05 23.7 0.0 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEP15097.1 - 4.7e-05 22.6 0.0 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 CEP15097.1 - 0.0012 18.2 0.0 0.032 13.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CEP15097.1 - 0.0017 18.5 0.2 0.24 11.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEP15097.1 - 0.002 17.5 0.1 0.0093 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEP15097.1 - 0.0023 17.4 0.5 0.0087 15.5 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CEP15097.1 - 0.0049 17.1 0.3 0.047 13.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CEP15097.1 - 0.0071 16.2 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CEP15097.1 - 0.012 15.2 0.5 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CEP15097.1 - 0.074 13.8 0.1 0.79 10.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 CEP15097.1 - 0.089 12.7 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 CEP15097.1 - 0.11 12.3 0.7 0.54 10.2 0.0 2.5 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 CEP15097.1 - 0.12 12.1 0.4 5 6.9 0.3 2.6 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 CEP15097.1 - 0.14 11.7 1.8 9.6 5.8 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase ABC2_membrane_2 PF12679.2 CEP15097.1 - 0.33 9.7 25.9 0.014 14.2 2.1 2.9 4 0 0 4 4 3 0 ABC-2 family transporter protein AAA_28 PF13521.1 CEP15097.1 - 0.38 10.6 3.3 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CEP15097.1 - 2.8 8.2 7.4 0.63 10.3 0.2 2.8 3 0 0 3 3 2 0 AAA domain DUF501 PF04417.7 CEP15098.1 - 0.26 11.1 2.1 0.7 9.7 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Tweety PF04906.8 CEP15098.1 - 0.63 8.3 3.1 0.87 7.9 2.2 1.2 1 0 0 1 1 1 0 Tweety NAF PF03822.9 CEP15098.1 - 0.74 9.5 4.0 2.1 8.1 0.1 3.1 2 1 1 3 3 3 0 NAF domain RBD-FIP PF09457.5 CEP15098.1 - 2.3 8.0 6.4 1.9 8.3 1.0 3.5 4 0 0 4 4 4 0 FIP domain DUF3450 PF11932.3 CEP15098.1 - 3.1 6.9 13.3 0.23 10.6 5.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 CEP15098.1 - 8.6 6.6 9.0 5 7.4 4.0 2.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Rieske PF00355.21 CEP15099.1 - 1.4e-07 30.9 0.1 2.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SR-25 PF10500.4 CEP15099.1 - 8.6e-05 22.1 26.4 0.00032 20.2 4.9 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein BLVR PF06375.6 CEP15099.1 - 0.0013 18.5 8.5 0.0013 18.5 5.9 2.1 2 0 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) Amino_oxidase PF01593.19 CEP15099.1 - 0.0097 15.0 0.0 0.017 14.1 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Herpes_LMP2 PF07415.6 CEP15099.1 - 0.2 10.2 0.4 0.29 9.6 0.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein RR_TM4-6 PF06459.7 CEP15099.1 - 0.27 11.1 12.3 1.4 8.7 1.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 CEP15099.1 - 0.55 9.3 7.8 0.91 8.6 0.4 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain CAF-1_p150 PF11600.3 CEP15099.1 - 0.76 9.1 26.9 1.5 8.1 7.6 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 CEP15099.1 - 0.9 7.7 11.6 1.2 7.3 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Rtf2 PF04641.7 CEP15099.1 - 1.4 8.0 15.4 0.039 13.1 3.1 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3513 PF12026.3 CEP15099.1 - 2.3 7.7 10.0 3.3 7.1 1.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3513) Peptidase_S49_N PF08496.5 CEP15099.1 - 3.4 7.4 11.8 0.32 10.7 3.8 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4519 PF15012.1 CEP15099.1 - 7.4 6.5 12.6 17 5.3 8.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF1980 PF09323.5 CEP15099.1 - 9.7 5.8 11.3 2.8 7.6 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) IGR PF09597.5 CEP15100.1 - 3.5e-24 84.4 0.1 4.3e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 IGR protein motif MatE PF01554.13 CEP15101.1 - 1.4e-48 164.5 19.6 2.5e-28 98.7 5.8 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 CEP15101.1 - 1.1e-07 31.7 10.1 1.1e-07 31.7 7.0 3.6 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain SNARE_assoc PF09335.6 CEP15103.1 - 2.2e-14 53.7 3.4 2.2e-14 53.7 2.4 2.9 3 1 0 3 3 3 1 SNARE associated Golgi protein HAMP PF00672.20 CEP15103.1 - 0.019 15.1 1.8 0.22 11.7 0.0 2.7 2 0 0 2 2 2 0 HAMP domain DUF2852 PF11014.3 CEP15103.1 - 0.18 11.7 0.7 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF4212 PF13937.1 CEP15103.1 - 10 6.2 12.2 0.14 12.1 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Nucleoporin_N PF08801.6 CEP15104.1 - 1.6e-53 181.9 0.4 2.5e-53 181.3 0.3 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 CEP15104.1 - 1.1e-35 123.2 8.2 1.6e-35 122.7 5.7 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal OB_NTP_bind PF07717.11 CEP15104.1 - 7e-26 90.2 0.0 1.5e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CEP15104.1 - 2.7e-22 78.6 0.0 5.9e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEP15104.1 - 1e-12 47.6 0.0 2.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP15104.1 - 6e-08 32.3 0.2 1.5e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEP15104.1 - 0.00015 21.9 0.3 0.00092 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CEP15104.1 - 0.0042 16.6 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CEP15104.1 - 0.1 12.0 0.1 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain WD40 PF00400.27 CEP15105.1 - 1.2e-62 205.6 14.3 2.1e-09 36.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Glucosamine_iso PF01182.15 CEP15106.1 - 2.8e-21 76.1 0.0 4.3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PDEase_I PF00233.14 CEP15107.1 - 9.3e-59 199.0 1.8 4e-57 193.6 1.2 2.4 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.19 CEP15107.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Response regulator receiver domain DUF4218 PF13960.1 CEP15108.1 - 0.067 12.6 0.3 0.073 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) UDG PF03167.14 CEP15109.1 - 1.5e-15 56.9 0.0 2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RNA_pol_Rpc82 PF05645.8 CEP15110.1 - 6.2e-23 81.6 0.8 1.3e-22 80.5 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 CEP15110.1 - 1.5e-21 76.0 0.3 1.6e-16 59.9 0.0 3.6 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 CEP15110.1 - 1.1e-05 24.9 3.2 0.016 14.7 0.0 4.0 2 1 2 4 4 4 2 TFIIE alpha subunit TrmB PF01978.14 CEP15110.1 - 6.8e-05 22.4 0.1 0.77 9.5 0.0 4.2 4 0 0 4 4 4 2 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 CEP15110.1 - 0.062 12.8 0.3 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain Coatomer_E PF04733.9 CEP15112.1 - 9.8e-82 274.3 7.3 1.1e-81 274.1 5.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit Apc3 PF12895.2 CEP15112.1 - 6.3e-07 29.4 6.3 0.004 17.2 0.3 3.8 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CEP15112.1 - 9.5e-07 29.0 12.7 0.014 15.7 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP15112.1 - 1.1e-06 28.5 5.8 0.00067 19.5 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 CEP15112.1 - 4.2e-05 23.5 5.8 0.014 15.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP15112.1 - 0.00026 21.5 5.8 0.18 12.5 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP15112.1 - 0.00029 21.1 8.8 0.25 12.0 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEP15112.1 - 0.00061 19.3 0.7 0.064 12.9 0.1 3.0 2 1 0 2 2 2 1 TPR repeat RPN7 PF10602.4 CEP15112.1 - 0.00065 19.1 0.8 0.0064 15.8 0.6 2.2 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_1 PF00515.23 CEP15112.1 - 0.016 14.8 0.9 2.1 8.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 CEP15112.1 - 0.039 14.0 2.2 1.2 9.3 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP15112.1 - 0.12 12.3 10.2 0.16 11.9 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 CEP15112.1 - 0.39 10.6 9.0 0.064 13.2 1.4 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat Snf7 PF03357.16 CEP15114.1 - 6e-37 126.6 21.5 8.2e-37 126.2 14.9 1.1 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 CEP15114.1 - 0.032 13.6 0.1 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Ycf4 PF02392.11 CEP15114.1 - 0.1 11.9 1.0 0.15 11.3 0.7 1.3 1 0 0 1 1 1 0 Ycf4 PglZ PF08665.7 CEP15114.1 - 0.21 11.2 4.4 0.27 10.8 2.6 1.5 1 1 0 1 1 1 0 PglZ domain V_ATPase_I PF01496.14 CEP15114.1 - 2.2 6.0 11.2 2.7 5.7 7.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PTR2 PF00854.16 CEP15115.1 - 2.7e-60 204.1 10.4 6.4e-60 202.8 7.2 1.6 1 0 0 1 1 1 1 POT family Translin PF01997.11 CEP15116.1 - 1e-43 149.3 0.1 1.2e-43 149.1 0.1 1.0 1 0 0 1 1 1 1 Translin family Glyco_hydro_53 PF07745.8 CEP15116.1 - 0.00015 20.6 0.4 0.00039 19.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 CLASP_N PF12348.3 CEP15116.1 - 0.033 13.5 0.0 0.087 12.1 0.0 1.6 2 0 0 2 2 2 0 CLASP N terminal M157 PF11624.3 CEP15116.1 - 0.11 11.5 0.1 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 MHC class I-like protein M157 Allantoicase PF03561.10 CEP15117.1 - 8.7e-80 265.5 0.0 8.1e-42 142.2 0.0 2.3 2 1 0 2 2 2 2 Allantoicase repeat DUF953 PF06110.6 CEP15118.1 - 1.3e-24 85.9 0.0 1.4e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 CEP15118.1 - 0.00047 20.1 0.0 0.0013 18.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 CEP15118.1 - 0.0019 17.8 0.2 0.0048 16.5 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 CEP15118.1 - 0.04 13.4 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin RVT_1 PF00078.22 CEP15119.1 - 5.8e-34 117.3 0.0 1.2e-33 116.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP15119.1 - 1.7e-10 41.2 1.1 3.1e-10 40.4 0.8 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP15119.1 - 1.5e-09 37.5 1.8 2.2e-09 36.9 0.2 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CEP15119.1 - 2.4e-06 27.7 0.7 8.2e-06 26.0 0.5 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 CEP15119.1 - 0.00075 19.3 15.7 0.012 15.5 1.6 2.8 2 0 0 2 2 2 2 Zinc knuckle Cofilin_ADF PF00241.15 CEP15120.1 - 2.4e-16 59.7 0.0 2.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF815 PF05673.8 CEP15120.1 - 0.084 11.7 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CAP18_C PF12153.3 CEP15120.1 - 0.14 11.8 0.6 0.31 10.7 0.4 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) UCH PF00443.24 CEP15121.1 - 9.5e-43 146.2 0.1 1.4e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CEP15121.1 - 5.6e-13 48.7 0.4 1.3e-12 47.6 0.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CEP15121.1 - 1.4e-10 41.0 0.1 5.3e-10 39.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fork_head PF00250.13 CEP15122.1 - 2.8e-39 133.0 0.5 7.5e-39 131.6 0.3 1.7 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CEP15122.1 - 2.7e-12 46.6 0.0 6.5e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain adh_short PF00106.20 CEP15123.1 - 3.8e-18 65.9 0.0 4.6e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP15123.1 - 3.3e-07 30.3 0.0 4.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP15123.1 - 2.1e-05 24.2 0.0 2.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CEP15123.1 - 0.00036 20.2 0.2 0.00073 19.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CEP15123.1 - 0.017 14.5 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEP15123.1 - 0.061 12.0 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CEP15123.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 CEP15123.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Herpes_UL49_5 PF05702.6 CEP15123.1 - 0.46 10.3 2.2 0.86 9.5 0.9 1.8 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Hydrolase PF00702.21 CEP15125.1 - 2e-26 93.7 0.2 1.5e-24 87.6 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CEP15125.1 - 1.9e-25 89.4 10.2 1.9e-24 86.1 3.1 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.15 CEP15125.1 - 1.8e-23 82.8 2.1 1.8e-23 82.8 1.5 3.0 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CEP15125.1 - 4.1e-18 65.1 0.0 7.7e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP15125.1 - 1.8e-12 47.8 0.0 9.3e-12 45.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP15125.1 - 0.0087 15.6 2.0 0.029 13.9 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3753 PF12575.3 CEP15125.1 - 6.5 6.6 10.1 14 5.5 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3753) E1-E2_ATPase PF00122.15 CEP15126.1 - 3.3e-29 101.5 0.3 4.9e-29 101.0 0.0 1.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 CEP15126.1 - 2.7e-17 61.9 0.0 4.9e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Raffinose_syn PF05691.7 CEP15127.1 - 2.2e-52 177.6 9.7 7.3e-39 132.9 3.8 3.9 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 TFIIA PF03153.8 CEP15128.1 - 0.11 12.3 16.4 0.017 15.0 7.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CEP15128.1 - 0.15 11.4 16.1 0.23 10.8 11.2 1.2 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 CEP15128.1 - 0.27 10.9 7.0 0.48 10.1 4.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CEP15128.1 - 0.42 10.6 13.8 0.76 9.8 9.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF_4EBP PF05456.6 CEP15128.1 - 1.9 8.2 13.7 1.9 8.2 8.2 1.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF4602 PF15375.1 CEP15128.1 - 2.7 8.0 13.3 5.2 7.1 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) DUF4557 PF15101.1 CEP15128.1 - 2.7 7.7 16.0 5 6.9 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) COX6B PF02297.12 CEP15129.1 - 7.1e-21 74.0 7.0 8.7e-21 73.7 4.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 CEP15129.1 - 0.0018 17.6 0.2 0.0026 17.1 0.1 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain AAA_33 PF13671.1 CEP15129.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain UCR_hinge PF02320.11 CEP15129.1 - 0.062 13.2 0.5 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.9 CEP15132.1 - 4 5.3 6.1 4.9 5.0 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Metallophos PF00149.23 CEP15133.1 - 5.1e-40 137.0 1.8 7.4e-40 136.4 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Zds_C PF08632.5 CEP15134.1 - 9.3e-21 72.9 0.8 9.3e-21 72.9 0.5 2.7 4 0 0 4 4 4 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Cation_ATPase_C PF00689.16 CEP15135.1 - 1.7e-10 40.6 18.4 1.7e-10 40.6 12.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Pro_isomerase PF00160.16 CEP15136.1 - 6.6e-45 153.0 0.0 7.4e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ligase_CoA PF00549.14 CEP15136.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 CoA-ligase RRM_1 PF00076.17 CEP15137.1 - 4.1e-33 112.8 0.1 5.9e-17 61.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP15137.1 - 9.8e-25 86.3 0.0 7.7e-14 51.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP15137.1 - 1.9e-13 50.0 0.2 7.1e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP15137.1 - 3.9e-06 26.5 0.2 0.0025 17.5 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Vpu PF00558.14 CEP15137.1 - 0.41 10.2 2.3 1.2 8.7 1.6 1.8 1 0 0 1 1 1 0 Vpu protein zf-met PF12874.2 CEP15138.1 - 0.00063 19.8 0.3 0.0011 19.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP15138.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CEP15138.1 - 0.068 13.2 1.4 0.18 11.9 1.0 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF3505 PF12013.3 CEP15138.1 - 0.74 10.0 6.1 0.19 11.9 1.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3505) B56 PF01603.15 CEP15139.1 - 1.6e-157 524.3 12.7 1.1e-104 350.2 1.7 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Recep_L_domain PF01030.19 CEP15139.1 - 0.076 12.9 0.4 2 8.4 0.3 2.6 1 1 0 1 1 1 0 Receptor L domain PfkB PF00294.19 CEP15140.1 - 3.5e-26 92.0 0.3 1.2e-25 90.3 0.2 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Pup_ligase PF03136.10 CEP15140.1 - 0.043 12.4 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Pup-ligase protein DFP PF04127.10 CEP15140.1 - 0.087 12.4 0.2 0.087 12.4 0.1 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Ldh_1_N PF00056.18 CEP15141.1 - 3.1e-45 153.4 0.1 5.2e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CEP15141.1 - 2.4e-44 151.1 0.1 3.6e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CEP15141.1 - 1e-05 24.4 0.0 1.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CEP15141.1 - 0.00056 20.1 0.3 0.002 18.3 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CEP15141.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 CEP15141.1 - 0.0083 16.1 0.6 0.017 15.1 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CEP15141.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_4 PF02056.11 CEP15141.1 - 0.024 13.9 0.0 1.8 7.8 0.1 2.4 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Cyanate_lyase PF02560.9 CEP15142.1 - 2.4e-28 97.4 0.1 4.1e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 CEP15142.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix Homeobox PF00046.24 CEP15142.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Homeobox domain Sugar_tr PF00083.19 CEP15143.1 - 9.4e-127 423.2 26.2 1.1e-126 423.0 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP15143.1 - 3.2e-23 82.0 42.2 9.4e-18 64.0 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Melittin PF01372.12 CEP15143.1 - 0.081 12.2 0.0 0.32 10.3 0.0 2.1 1 0 0 1 1 1 0 Melittin Lig_chan PF00060.21 CEP15143.1 - 0.089 12.5 1.3 0.35 10.5 0.9 2.1 1 0 0 1 1 1 0 Ligand-gated ion channel FAT PF02259.18 CEP15144.1 - 3.6e-67 226.8 11.2 3.6e-67 226.8 7.7 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 CEP15144.1 - 1.2e-23 83.8 0.8 4.2e-23 82.0 0.3 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CEP15144.1 - 1.8e-06 27.2 0.5 4.6e-06 25.9 0.4 1.8 1 0 0 1 1 1 1 FATC domain GSDH PF07995.6 CEP15144.1 - 0.048 12.7 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase RVT_1 PF00078.22 CEP15145.1 - 1.9e-10 40.5 0.0 3.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_21 PF02992.9 CEP15147.1 - 0.0057 15.7 0.4 0.028 13.4 0.0 2.0 2 1 0 2 2 2 1 Transposase family tnp2 DKCLD PF08068.7 CEP15148.1 - 2.8e-31 107.2 0.1 1e-29 102.2 0.1 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CEP15148.1 - 8.1e-24 84.4 0.2 4.1e-21 75.7 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CEP15148.1 - 3e-19 68.4 0.9 6e-19 67.5 0.6 1.5 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 CEP15148.1 - 0.76 9.4 22.3 1.1 8.8 15.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 CEP15148.1 - 8 5.5 12.1 12 4.9 8.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TrkH PF02386.11 CEP15149.1 - 2.8e-79 266.2 13.9 1.9e-78 263.5 7.8 2.1 2 0 0 2 2 2 2 Cation transport protein ZZ PF00569.12 CEP15150.1 - 8.4e-24 82.8 39.5 3.2e-09 36.1 4.5 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type PB1 PF00564.19 CEP15150.1 - 0.098 12.3 1.3 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 PB1 domain TT_ORF1 PF02956.9 CEP15150.1 - 7.1 4.9 8.1 2.1 6.6 2.4 2.2 2 0 0 2 2 2 0 TT viral orf 1 PIP5K PF01504.13 CEP15151.1 - 5.9e-83 277.8 1.6 9.1e-83 277.2 1.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_hydro_3 PF00933.16 CEP15152.1 - 3.7e-64 216.5 0.0 5.4e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_7 PF13508.1 CEP15152.1 - 2.5e-18 65.9 0.1 3.8e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP15152.1 - 4e-17 62.2 0.4 4.7e-08 32.9 0.0 3.7 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP15152.1 - 4.4e-17 61.8 0.0 2.2e-10 40.4 0.0 3.0 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP15152.1 - 1.1e-11 44.8 0.0 9.3e-08 32.2 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEP15152.1 - 8.7e-06 25.5 0.0 0.02 14.7 0.0 2.5 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase FR47 PF08445.5 CEP15152.1 - 1.4e-05 24.7 0.0 0.2 11.4 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_6 PF13480.1 CEP15152.1 - 8.8e-05 22.4 0.0 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEP15152.1 - 0.00096 19.1 0.0 0.0046 16.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP15152.1 - 0.0078 16.3 0.0 0.055 13.6 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 CEP15152.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain OrfB_Zn_ribbon PF07282.6 CEP15153.1 - 0.028 14.0 0.1 0.26 10.9 0.0 2.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DUF421 PF04239.7 CEP15153.1 - 0.55 9.7 3.9 0.76 9.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF421) Sec2p PF06428.6 CEP15154.1 - 4.7e-13 48.8 18.1 4.7e-13 48.8 12.5 2.4 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF836 PF05768.9 CEP15154.1 - 0.049 13.8 2.8 0.045 14.0 0.7 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) GAS PF13851.1 CEP15154.1 - 4.6 6.3 40.2 21 4.2 27.6 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Glucan_synthase PF02364.10 CEP15154.1 - 6.2 4.5 11.0 8.7 4.0 7.6 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Velvet PF11754.3 CEP15155.1 - 9.5e-37 126.5 0.0 1.2e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Velvet factor DEAD PF00270.24 CEP15156.1 - 8.2e-42 142.5 0.3 1.4e-41 141.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S19 PF00203.16 CEP15156.1 - 2e-31 107.4 0.4 2e-31 107.4 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein S19 Helicase_C PF00271.26 CEP15156.1 - 6.5e-21 73.9 0.0 3.7e-11 42.7 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CEP15156.1 - 0.00025 20.9 0.0 0.00025 20.9 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 CEP15156.1 - 0.15 11.6 1.0 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 Helicase Usp PF00582.21 CEP15158.1 - 6.7e-08 32.8 0.0 9.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF4165 PF13752.1 CEP15158.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) ATP_bind_1 PF03029.12 CEP15158.1 - 0.079 12.4 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF2015 PF09435.5 CEP15159.1 - 6e-33 113.3 0.0 6.6e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF3301 PF11743.3 CEP15159.1 - 0.015 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) MLANA PF14991.1 CEP15159.1 - 0.057 13.4 0.1 0.087 12.8 0.1 1.6 1 1 0 1 1 1 0 Protein melan-A CTC1 PF15489.1 CEP15160.1 - 3.7e-27 94.1 0.1 1.1e-22 79.3 0.0 2.3 2 0 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 Glyco_transf_15 PF01793.11 CEP15161.1 - 3.2e-106 355.0 13.9 4.7e-106 354.4 9.6 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3097 PF11296.3 CEP15161.1 - 0.0056 15.7 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3097) MSC PF09402.5 CEP15161.1 - 0.044 12.5 0.8 0.53 8.9 0.0 2.1 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain PAP_central PF04928.12 CEP15162.1 - 1.5e-103 345.0 0.0 2e-103 344.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CEP15162.1 - 1.1e-36 125.7 0.0 1.8e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CEP15162.1 - 1.3e-07 31.8 0.0 2.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ank_2 PF12796.2 CEP15163.1 - 0.00033 20.9 0.0 0.001 19.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP15163.1 - 0.0022 18.4 0.1 0.0052 17.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SPT16 PF08644.6 CEP15163.1 - 0.043 13.6 5.8 0.44 10.3 0.0 3.8 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) Ank_5 PF13857.1 CEP15163.1 - 0.1 12.9 0.1 0.46 10.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TPR_11 PF13414.1 CEP15164.1 - 3.5e-60 199.5 16.8 1.8e-14 53.0 0.1 7.2 2 2 4 8 8 8 8 TPR repeat TPR_1 PF00515.23 CEP15164.1 - 2.7e-46 153.3 9.8 8e-08 31.5 0.0 11.0 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 CEP15164.1 - 1e-44 146.8 3.1 6.9e-07 28.7 0.0 11.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 CEP15164.1 - 6.1e-31 106.4 0.1 5.2e-06 26.9 0.0 6.3 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 CEP15164.1 - 9.4e-28 93.8 8.5 0.0029 17.2 0.0 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 CEP15164.1 - 5.7e-27 93.4 12.7 2e-05 24.4 0.1 7.5 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 CEP15164.1 - 1.2e-24 84.3 4.7 8.5e-06 25.5 0.0 10.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 CEP15164.1 - 4.5e-21 73.4 0.1 0.061 13.9 0.0 8.7 4 1 6 10 10 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 CEP15164.1 - 2.4e-18 64.3 1.5 0.046 13.5 0.0 9.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 CEP15164.1 - 3.8e-18 65.5 7.7 9.5e-06 25.8 0.2 7.0 7 1 1 8 8 6 4 Tetratricopeptide repeat Apc3 PF12895.2 CEP15164.1 - 8.7e-13 48.2 8.1 0.00022 21.3 0.0 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CEP15164.1 - 1.2e-09 37.8 2.6 0.016 15.0 0.0 5.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 CEP15164.1 - 1.4e-09 37.3 0.6 0.039 12.9 0.0 5.3 1 1 4 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.3 CEP15164.1 - 2.9e-09 36.2 0.4 0.015 14.1 0.0 3.8 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 CEP15164.1 - 6.8e-09 35.6 7.4 2.5 8.7 0.0 9.2 10 1 0 10 10 9 1 Tetratricopeptide repeat BTAD PF03704.12 CEP15164.1 - 1.8e-06 28.2 0.2 0.24 11.6 0.1 4.0 4 1 0 4 4 3 2 Bacterial transcriptional activator domain TPR_5 PF12688.2 CEP15164.1 - 2.4e-06 27.5 0.3 0.041 13.9 0.0 3.8 3 2 1 4 4 4 2 Tetratrico peptide repeat TPR_10 PF13374.1 CEP15164.1 - 4.3e-05 23.2 1.0 0.5 10.3 0.1 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 CEP15164.1 - 0.00059 19.7 9.6 4.3 7.2 0.3 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Clathrin PF00637.15 CEP15164.1 - 0.0058 16.2 0.2 0.25 10.9 0.0 3.3 2 1 1 3 3 3 1 Region in Clathrin and VPS 14-3-3 PF00244.15 CEP15164.1 - 0.013 14.5 0.7 0.56 9.2 0.0 3.3 3 1 1 4 4 4 0 14-3-3 protein MIT PF04212.13 CEP15164.1 - 0.022 14.6 9.4 4.6 7.2 0.0 6.2 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain DUF3808 PF10300.4 CEP15164.1 - 0.037 12.6 1.1 0.51 8.8 0.0 3.0 2 1 1 4 4 4 0 Protein of unknown function (DUF3808) ArsR PF09824.4 CEP15164.1 - 0.045 13.0 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 0 ArsR transcriptional regulator DUF357 PF04010.8 CEP15164.1 - 0.098 12.3 4.5 0.27 10.9 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF357) NAP PF00956.13 CEP15165.1 - 2.7e-23 82.3 7.3 6e-23 81.2 5.1 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Ribosomal_L18e PF00828.14 CEP15166.1 - 3.8e-24 85.5 0.4 3.8e-24 85.5 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Polysacc_deac_3 PF15421.1 CEP15166.1 - 0.095 11.3 0.1 0.43 9.2 0.0 1.8 1 1 1 2 2 2 0 Putative polysaccharide deacetylase Methyltransf_32 PF13679.1 CEP15166.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Spindle_Spc25 PF08234.7 CEP15167.1 - 2.1e-15 56.4 0.2 9.8e-15 54.3 0.1 2.2 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF1735 PF08522.5 CEP15167.1 - 0.00032 21.0 1.7 0.87 10.0 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF1735) DUF342 PF03961.8 CEP15167.1 - 0.05 12.0 17.4 0.074 11.4 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 CEP15167.1 - 0.61 10.1 26.0 0.31 11.0 9.0 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 CEP15167.1 - 1.2 8.9 13.9 0.33 10.7 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2992 PF11208.3 CEP15167.1 - 1.4 8.7 16.3 2.7 7.9 11.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Exonuc_VII_L PF02601.10 CEP15167.1 - 4.5 6.3 17.7 5.7 6.0 12.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mcp5_PH PF12814.2 CEP15168.1 - 1.7e-18 66.7 1.2 5.7e-18 65.0 0.8 2.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology CENP-F_leu_zip PF10473.4 CEP15168.1 - 2.5 7.9 32.2 0.15 11.9 1.5 3.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 USP7_ICP0_bdg PF12436.3 CEP15169.1 - 4.1e-59 199.8 0.1 8.1e-59 198.8 0.1 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 CEP15169.1 - 1.9e-57 194.4 0.3 3.2e-57 193.6 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CEP15169.1 - 2.4e-48 164.4 5.1 9.9e-46 155.8 0.9 3.3 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 CEP15169.1 - 9.9e-31 107.2 0.2 2.5e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CEP15169.1 - 4e-10 39.9 0.5 2.1e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 MATH domain UQ_con PF00179.21 CEP15170.1 - 2e-21 75.8 0.0 1e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme EMP24_GP25L PF01105.19 CEP15171.1 - 1.6e-46 158.3 0.3 2e-46 158.0 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Jnk-SapK_ap_N PF09744.4 CEP15171.1 - 0.038 13.9 0.7 0.038 13.9 0.5 1.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF904 PF06005.7 CEP15171.1 - 0.072 13.3 1.7 0.14 12.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Aminotran_5 PF00266.14 CEP15172.1 - 4.6e-24 84.8 0.1 6.2e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CEP15172.1 - 0.00021 20.3 0.0 0.00028 19.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Big_3_3 PF13750.1 CEP15174.1 - 0.27 10.6 1.3 0.4 10.0 0.9 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) rve PF00665.21 CEP15175.1 - 4.1e-12 46.2 0.0 9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP15175.1 - 3.2e-11 42.7 0.1 6.7e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP15175.1 - 0.041 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain AAA_16 PF13191.1 CEP15176.1 - 5.8e-09 36.1 0.0 7.4e-08 32.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.1 CEP15176.1 - 1.1e-06 28.4 0.9 0.13 12.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 CEP15176.1 - 0.00054 20.1 0.2 0.012 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Guanylate_cyc PF00211.15 CEP15176.1 - 0.0066 15.8 0.0 0.11 11.8 0.0 2.7 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain AAA_17 PF13207.1 CEP15176.1 - 0.01 16.6 0.0 0.057 14.2 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEP15176.1 - 0.11 12.4 0.4 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Nsp1 PF11501.3 CEP15176.1 - 0.14 12.0 0.0 0.5 10.2 0.0 1.9 1 0 0 1 1 1 0 Non structural protein Nsp1 AA_permease PF00324.16 CEP15177.1 - 1.8e-125 419.0 42.8 2.3e-125 418.6 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEP15177.1 - 3.8e-43 147.6 44.1 4.7e-43 147.2 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease Rad21_Rec8_N PF04825.8 CEP15178.1 - 6.9e-35 119.3 0.2 1.2e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CEP15178.1 - 1.2e-13 49.9 0.0 2.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CEP15178.1 - 5.6e-05 22.8 0.1 0.0003 20.4 0.0 2.0 2 0 0 2 2 2 1 ScpA/B protein Octopine_DH PF02317.12 CEP15178.1 - 0.14 11.8 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain G-alpha PF00503.15 CEP15179.1 - 9.9e-131 436.0 4.3 1.2e-130 435.6 3.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP15179.1 - 1.2e-15 57.1 1.3 1.7e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CEP15179.1 - 0.002 18.6 0.2 1.5 9.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 CEP15179.1 - 0.0051 15.9 5.6 0.057 12.5 0.2 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CEP15179.1 - 0.037 13.5 0.1 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_BTRF1 PF04682.7 CEP15179.1 - 0.053 12.8 0.2 0.099 11.9 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region MMR_HSR1 PF01926.18 CEP15179.1 - 0.14 12.1 0.0 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-C3HC4 PF00097.20 CEP15180.1 - 4.2e-09 35.9 10.8 4.2e-09 35.9 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP15180.1 - 9.8e-09 35.1 11.0 9.8e-09 35.1 7.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CEP15180.1 - 1.2e-08 34.6 3.1 1.2e-08 34.6 2.2 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CEP15180.1 - 2.1e-08 33.7 8.8 2.1e-08 33.7 6.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP15180.1 - 6.8e-07 28.8 6.4 6.8e-07 28.8 4.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP15180.1 - 7.5e-07 28.8 8.9 7.5e-07 28.8 6.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CEP15180.1 - 0.00073 19.2 2.9 0.00073 19.2 2.0 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 CEP15180.1 - 0.0023 18.0 9.5 0.0028 17.7 3.3 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CEP15180.1 - 0.0025 17.3 13.9 0.04 13.4 1.5 3.3 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 CEP15180.1 - 0.0029 17.4 1.5 0.0029 17.4 1.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CEP15180.1 - 0.011 15.5 8.2 0.011 15.5 5.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING U-box PF04564.10 CEP15180.1 - 0.051 13.5 3.4 0.48 10.4 0.0 3.3 4 1 1 5 5 4 0 U-box domain zf-C2HC_2 PF13913.1 CEP15180.1 - 0.31 10.7 11.3 0.21 11.2 0.3 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Nse PF11789.3 CEP15180.1 - 2.2 7.8 12.1 0.39 10.2 3.5 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.7 CEP15180.1 - 6 6.7 11.4 13 5.6 2.6 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF4203 PF13886.1 CEP15181.1 - 9.3e-17 61.1 31.0 9.3e-17 61.1 21.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) HMA PF00403.21 CEP15182.1 - 1.5e-68 226.8 0.4 7.4e-11 42.0 0.0 7.6 7 0 0 7 7 7 7 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 CEP15182.1 - 8e-50 169.0 2.5 8e-50 169.0 1.7 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEP15182.1 - 1.1e-36 127.2 0.0 7.5e-36 124.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP15182.1 - 2.3e-15 57.2 0.0 1.2e-14 54.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP15182.1 - 0.0002 21.0 0.2 0.003 17.1 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 CEP15183.1 - 2.2e-07 30.5 1.3 7.5e-07 28.7 0.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP15183.1 - 0.0029 17.2 0.0 0.0094 15.5 0.0 1.9 1 0 0 1 1 1 1 F-box domain Kinesin PF00225.18 CEP15184.1 - 2.3e-110 368.4 6.2 7.3e-63 212.2 0.0 3.8 2 1 1 3 3 3 2 Kinesin motor domain ABC2_membrane_3 PF12698.2 CEP15185.1 - 6.1 5.7 8.8 8.9 5.2 6.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Tub PF01167.13 CEP15186.1 - 4.1e-77 258.5 0.0 5.1e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 Tub family PRRSV_2b PF07069.6 CEP15187.1 - 0.76 10.1 5.6 21 5.4 1.3 2.5 2 1 1 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b TBCC PF07986.7 CEP15188.1 - 1.9e-24 85.3 3.0 3.6e-24 84.4 2.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF4482 PF14818.1 CEP15188.1 - 0.14 12.8 4.5 6.2 7.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) GPI-anchored PF10342.4 CEP15189.1 - 3.5e-09 37.0 1.3 5.6e-09 36.3 0.9 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med4 PF10018.4 CEP15190.1 - 8.9e-28 96.9 8.3 8.9e-28 96.9 5.7 1.3 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 MMR_HSR1_C PF08438.5 CEP15190.1 - 0.035 14.3 0.9 0.035 14.3 0.6 2.2 2 1 1 3 3 3 0 GTPase of unknown function C-terminal DUF2999 PF11212.3 CEP15190.1 - 0.09 12.8 1.6 0.25 11.4 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2999) Phage_HK97_TLTM PF06120.6 CEP15190.1 - 0.99 8.6 9.1 0.062 12.6 2.8 1.5 2 0 0 2 2 2 0 Tail length tape measure protein Histone_HNS PF00816.16 CEP15190.1 - 6.6 7.3 7.8 0.37 11.3 1.2 2.1 3 0 0 3 3 3 0 H-NS histone family DUF1640 PF07798.6 CEP15191.1 - 8.4e-55 185.5 10.9 1e-54 185.2 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.7 CEP15191.1 - 0.0028 17.4 11.5 0.0028 17.4 8.0 2.1 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 CEP15191.1 - 0.0041 16.5 6.8 0.0041 16.5 4.7 3.0 2 1 1 3 3 3 2 Septum formation initiator MRP-S27 PF10037.4 CEP15191.1 - 0.0072 15.2 3.7 0.0073 15.2 2.5 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Mitofilin PF09731.4 CEP15191.1 - 0.03 13.0 13.5 0.037 12.6 9.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FlaC_arch PF05377.6 CEP15191.1 - 0.037 13.9 12.1 0.097 12.5 2.8 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 CEP15191.1 - 0.094 12.4 12.0 0.41 10.4 0.9 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper Kinesin-relat_1 PF12711.2 CEP15191.1 - 0.1 12.9 9.5 0.59 10.5 1.7 2.4 2 0 0 2 2 2 0 Kinesin motor DUF724 PF05266.9 CEP15191.1 - 0.11 12.1 18.1 0.015 14.9 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3013 PF11217.3 CEP15191.1 - 0.3 10.8 4.1 0.09 12.5 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) DUF1451 PF07295.6 CEP15191.1 - 0.32 10.7 9.6 0.44 10.3 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) UPF0449 PF15136.1 CEP15191.1 - 0.35 11.1 12.0 0.62 10.3 2.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 V_ATPase_I PF01496.14 CEP15191.1 - 0.39 8.5 6.6 0.51 8.1 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 CEP15191.1 - 0.4 10.6 13.2 0.46 10.4 4.4 2.8 2 1 1 3 3 3 0 bZIP transcription factor XkdW PF09636.5 CEP15191.1 - 0.47 10.3 5.4 4.6 7.1 0.2 2.4 2 0 0 2 2 2 0 XkdW protein DUF3584 PF12128.3 CEP15191.1 - 0.55 7.5 17.9 0.67 7.2 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4239 PF14023.1 CEP15191.1 - 0.58 9.4 3.9 0.39 10.0 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) MbeB_N PF04837.7 CEP15191.1 - 0.8 9.8 14.1 0.55 10.3 1.7 3.7 3 1 1 4 4 4 0 MbeB-like, N-term conserved region Baculo_PEP_C PF04513.7 CEP15191.1 - 1.1 9.1 10.5 1.2 9.0 2.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ax_dynein_light PF10211.4 CEP15191.1 - 1.1 9.0 19.4 0.74 9.6 7.0 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF1843 PF08898.5 CEP15191.1 - 1.2 9.1 11.8 6.9 6.7 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Syntaxin PF00804.20 CEP15191.1 - 1.6 8.8 18.4 6.3e+02 0.6 12.8 2.4 1 1 0 1 1 1 0 Syntaxin Cytochrom_B562 PF07361.6 CEP15191.1 - 1.7 9.0 11.1 0.96 9.8 4.7 2.5 2 1 1 3 3 3 0 Cytochrome b562 COG5 PF10392.4 CEP15191.1 - 1.7 8.5 10.8 4.8 7.1 7.2 2.2 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF972 PF06156.8 CEP15191.1 - 1.9 8.8 13.8 0.71 10.2 4.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF972) MSV199 PF10553.4 CEP15191.1 - 2.3 8.0 8.2 5.5 6.8 1.9 2.7 2 1 0 2 2 2 0 MSV199 domain TMF_DNA_bd PF12329.3 CEP15191.1 - 2.4 8.0 18.2 4.2 7.2 7.2 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2115 PF09888.4 CEP15191.1 - 2.4 8.2 7.5 2.8 8.0 4.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) TBPIP PF07106.8 CEP15191.1 - 2.5 7.6 17.7 0.33 10.5 5.6 2.2 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PKK PF12474.3 CEP15191.1 - 2.6 7.7 18.4 7 6.3 12.8 1.6 1 1 0 1 1 1 0 Polo kinase kinase IncA PF04156.9 CEP15191.1 - 3 7.3 19.2 7.5 6.0 13.3 1.6 1 1 0 1 1 1 0 IncA protein DUF2935 PF11155.3 CEP15191.1 - 3.2 7.8 7.3 21 5.2 4.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Prefoldin_2 PF01920.15 CEP15191.1 - 3.3 7.5 23.0 1.4 8.6 2.2 3.1 2 1 0 2 2 2 0 Prefoldin subunit DUF1319 PF07028.6 CEP15191.1 - 3.4 7.8 15.8 0.23 11.6 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) bZIP_2 PF07716.10 CEP15191.1 - 4.1 7.2 17.0 2.8 7.8 4.9 3.3 2 1 1 3 3 3 0 Basic region leucine zipper Prominin PF05478.6 CEP15191.1 - 4.6 4.6 10.4 0.61 7.5 3.5 1.5 1 1 1 2 2 2 0 Prominin Hemagglutinin PF00509.13 CEP15191.1 - 5.3 5.0 7.8 2.4 6.1 0.3 2.1 2 0 0 2 2 2 0 Haemagglutinin Vps51 PF08700.6 CEP15191.1 - 8.4 6.3 13.3 5.5 6.9 2.4 3.6 2 1 1 3 3 3 0 Vps51/Vps67 Adeno_PIX PF03955.9 CEP15191.1 - 9.8 6.7 8.6 15 6.1 2.1 2.5 1 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) ECH PF00378.15 CEP15192.1 - 8.8e-77 257.5 1.3 1e-76 257.2 0.9 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CEP15192.1 - 0.0029 17.4 0.3 0.066 12.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 CorA PF01544.13 CEP15193.1 - 0.017 14.2 0.9 0.021 13.8 0.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Voltage_CLC PF00654.15 CEP15199.1 - 2.3e-83 280.1 25.1 2.3e-83 280.1 17.4 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CEP15199.1 - 2.4e-05 24.0 0.0 0.00025 20.7 0.0 2.4 2 0 0 2 2 2 1 CBS domain YecM PF06185.7 CEP15199.1 - 0.0027 16.9 0.1 0.014 14.6 0.1 1.9 2 0 0 2 2 2 1 YecM protein IFT57 PF10498.4 CEP15199.1 - 0.11 11.1 0.5 0.19 10.4 0.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CotH PF08757.6 CEP15201.1 - 1.3e-49 169.1 1.0 2.1e-49 168.5 0.7 1.2 1 0 0 1 1 1 1 CotH protein RYDR_ITPR PF01365.16 CEP15201.1 - 0.031 13.5 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 RIH domain zf-Apc11 PF12861.2 CEP15202.1 - 2.6e-35 120.1 11.7 2.9e-35 119.9 8.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CEP15202.1 - 4.5e-28 97.1 12.3 5.3e-28 96.9 8.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CEP15202.1 - 6.5e-06 25.8 17.6 3.1e-05 23.6 12.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP15202.1 - 6.1e-05 22.9 9.5 0.0025 17.7 6.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP15202.1 - 0.00034 20.2 10.1 0.0062 16.2 7.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEP15202.1 - 0.04 13.7 0.7 0.04 13.7 0.5 2.4 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CEP15202.1 - 0.052 13.2 12.4 0.22 11.1 5.8 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP15202.1 - 0.092 12.4 15.5 0.63 9.7 10.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CEP15202.1 - 0.34 10.4 4.2 0.51 9.8 2.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 CEP15202.1 - 0.83 9.3 6.1 1.5 8.5 4.2 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-HC5HC2H_2 PF13832.1 CEP15202.1 - 1.4 8.9 7.9 2.1 8.3 5.5 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 CEP15202.1 - 5.2 7.1 18.0 49 3.9 12.4 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CEP15202.1 - 8.3 6.5 13.1 37 4.4 8.6 2.2 1 1 1 2 2 2 0 RING-variant domain zf-RING_4 PF14570.1 CEP15202.1 - 9.5 5.8 15.8 16 5.1 5.9 2.7 1 1 2 3 3 3 0 RING/Ubox like zinc-binding domain Ribosomal_S8e PF01201.17 CEP15203.1 - 3.7e-47 159.7 1.3 3.7e-47 159.7 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S8e SPX PF03105.14 CEP15203.1 - 1.7e-32 113.3 1.4 1.7e-32 113.3 1.0 2.4 2 0 0 2 2 2 1 SPX domain Ribosomal_L5_C PF00673.16 CEP15203.1 - 5e-23 80.6 0.0 1.1e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CEP15203.1 - 4.7e-19 67.9 0.0 1.1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 CD34_antigen PF06365.7 CEP15204.1 - 0.011 15.4 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2627 PF11118.3 CEP15204.1 - 0.019 15.0 0.2 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Syndecan PF01034.15 CEP15204.1 - 0.042 13.5 0.1 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF912 PF06024.7 CEP15204.1 - 0.086 12.8 3.9 0.46 10.5 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 CEP15204.1 - 0.28 11.1 2.5 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Rsa3 PF14615.1 CEP15205.1 - 2.6e-12 45.8 0.0 8.6e-12 44.1 0.0 1.8 2 0 0 2 2 2 1 Ribosome-assembly protein 3 Nop14 PF04147.7 CEP15205.1 - 0.14 10.0 16.7 0.17 9.7 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family YqfQ PF14181.1 CEP15205.1 - 1.8 8.5 4.5 0.36 10.8 0.8 1.6 2 0 0 2 2 2 0 YqfQ-like protein DUF740 PF05340.7 CEP15205.1 - 3.6 5.8 8.9 4.2 5.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF2039 PF10217.4 CEP15206.1 - 2.1e-26 91.7 18.9 3.4e-26 91.0 13.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) ADK_lid PF05191.9 CEP15206.1 - 9.7 5.9 8.6 53 3.5 4.1 2.9 2 1 1 3 3 3 0 Adenylate kinase, active site lid OST3_OST6 PF04756.8 CEP15207.1 - 8.2e-22 77.4 1.9 8.2e-22 77.4 1.3 1.8 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 CEP15207.1 - 8.8e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin PHD PF00628.24 CEP15208.1 - 0.001 18.6 7.9 0.001 18.6 5.5 2.1 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 CEP15208.1 - 0.0076 15.5 5.0 0.018 14.3 3.4 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CEP15208.1 - 0.017 14.8 4.5 0.017 14.8 3.1 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Polysacc_deac_1 PF01522.16 CEP15209.1 - 3.4e-21 75.1 0.0 6.7e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DDE_3 PF13358.1 CEP15210.1 - 0.037 13.7 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease SQS_PSY PF00494.14 CEP15212.1 - 1.5e-45 155.6 0.0 1.8e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PYRIN PF02758.11 CEP15212.1 - 0.083 12.5 0.2 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain PhyH PF05721.8 CEP15214.1 - 5.7e-10 39.5 0.1 1.2e-09 38.5 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GDE_N PF12439.3 CEP15214.1 - 0.0064 15.7 0.1 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme N terminal Peptidase_C14 PF00656.17 CEP15215.1 - 3.2e-64 216.9 0.2 4e-64 216.6 0.2 1.1 1 0 0 1 1 1 1 Caspase domain RNA_pol_L_2 PF13656.1 CEP15216.1 - 8.2e-30 102.0 0.0 1.1e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CEP15216.1 - 1.8e-09 36.5 0.0 2.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Daxx PF03344.10 CEP15216.1 - 0.19 10.2 5.9 0.17 10.3 4.1 1.1 1 0 0 1 1 1 0 Daxx Family TP_methylase PF00590.15 CEP15217.1 - 2.6e-20 73.0 0.0 4.1e-20 72.3 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Myosin_tail_1 PF01576.14 CEP15218.1 - 0.00061 17.6 6.1 0.00068 17.5 4.2 1.0 1 0 0 1 1 1 1 Myosin tail GCN5L1 PF06320.8 CEP15218.1 - 0.0022 17.7 2.4 0.0028 17.4 1.7 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Apolipoprotein PF01442.13 CEP15218.1 - 0.0029 17.1 2.4 0.0042 16.6 1.6 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.6 CEP15218.1 - 0.011 14.3 0.3 0.012 14.2 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.9 CEP15218.1 - 0.021 14.7 1.1 0.023 14.6 0.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ApoLp-III PF07464.6 CEP15218.1 - 0.022 14.7 2.9 0.027 14.4 2.0 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.5 CEP15218.1 - 0.034 14.2 0.2 0.038 14.1 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LXG PF04740.7 CEP15218.1 - 0.051 13.3 2.9 0.081 12.7 2.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily ATP-synt_B PF00430.13 CEP15218.1 - 0.056 13.2 7.6 0.081 12.7 5.3 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) SPX PF03105.14 CEP15218.1 - 0.058 13.1 1.5 0.067 12.9 1.1 1.1 1 0 0 1 1 1 0 SPX domain DUF1664 PF07889.7 CEP15218.1 - 0.06 13.1 2.7 0.051 13.3 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.8 CEP15218.1 - 0.073 12.1 0.2 0.078 12.0 0.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF883 PF05957.8 CEP15218.1 - 0.079 13.3 8.8 0.12 12.7 3.8 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CCDC155 PF14662.1 CEP15218.1 - 0.11 12.0 3.5 0.15 11.6 2.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DivIVA PF05103.8 CEP15218.1 - 0.12 12.3 6.3 0.21 11.6 4.4 1.3 1 0 0 1 1 1 0 DivIVA protein Tektin PF03148.9 CEP15218.1 - 0.13 10.7 4.3 0.15 10.5 3.0 1.0 1 0 0 1 1 1 0 Tektin family GrpE PF01025.14 CEP15218.1 - 0.14 11.6 6.9 0.32 10.5 4.8 1.6 1 1 0 1 1 1 0 GrpE Prominin PF05478.6 CEP15218.1 - 0.16 9.5 0.0 0.15 9.5 0.0 1.0 1 0 0 1 1 1 0 Prominin WXG100 PF06013.7 CEP15218.1 - 0.19 11.7 2.5 1.9 8.5 0.2 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG HR1 PF02185.11 CEP15218.1 - 0.19 11.4 5.2 0.28 10.9 3.6 1.4 1 0 0 1 1 1 0 Hr1 repeat IncA PF04156.9 CEP15218.1 - 0.2 11.2 3.0 0.27 10.8 2.1 1.2 1 0 0 1 1 1 0 IncA protein HAUS-augmin3 PF14932.1 CEP15218.1 - 0.23 10.6 1.9 0.27 10.4 1.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ADIP PF11559.3 CEP15218.1 - 0.26 11.1 4.6 0.31 10.9 3.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 CEP15218.1 - 0.29 10.0 5.1 0.41 9.5 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.1 CEP15218.1 - 0.33 10.7 2.6 0.4 10.5 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3560 PF12083.3 CEP15218.1 - 0.37 10.8 6.4 0.48 10.4 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Cep57_CLD_2 PF14197.1 CEP15218.1 - 0.39 10.6 7.0 0.6 10.0 4.9 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Macoilin PF09726.4 CEP15218.1 - 0.39 8.9 2.7 0.45 8.7 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Prefoldin_2 PF01920.15 CEP15218.1 - 0.44 10.3 3.9 1.8 8.3 2.7 1.9 1 1 0 1 1 1 0 Prefoldin subunit KfrA_N PF11740.3 CEP15218.1 - 0.47 10.8 7.8 0.64 10.4 5.4 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF3713 PF12506.3 CEP15218.1 - 0.49 10.4 3.1 0.8 9.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) AAA_13 PF13166.1 CEP15218.1 - 0.55 8.6 5.7 0.61 8.4 4.0 1.0 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CEP15218.1 - 0.58 9.1 3.3 0.63 9.0 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 CEP15218.1 - 0.68 7.1 4.7 0.7 7.1 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ISG65-75 PF11727.3 CEP15218.1 - 0.96 8.4 5.3 1.1 8.2 3.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein HisKA_3 PF07730.8 CEP15218.1 - 1.4 9.2 4.7 3.7 7.9 1.0 2.1 1 1 1 2 2 2 0 Histidine kinase Atg14 PF10186.4 CEP15218.1 - 2.5 6.9 4.5 2.8 6.7 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3987 PF13148.1 CEP15218.1 - 2.7 6.4 6.2 3.1 6.2 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RRF PF01765.14 CEP15218.1 - 6 6.3 8.0 9.4 5.6 5.1 1.5 1 1 1 2 2 2 0 Ribosome recycling factor Nup96 PF12110.3 CEP15219.1 - 5.1e-14 52.0 3.8 5.1e-14 52.0 2.6 3.0 3 1 0 3 3 3 1 Nuclear protein 96 DUF4485 PF14846.1 CEP15219.1 - 0.14 11.8 2.0 0.79 9.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) MoaE PF02391.12 CEP15220.1 - 1.6e-33 114.9 0.1 2e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Pkinase PF00069.20 CEP15221.1 - 1.2e-68 231.0 0.0 1.9e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15221.1 - 1.5e-32 112.6 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 CEP15221.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Ribosomal_L10 PF00466.15 CEP15222.1 - 1.8e-20 72.7 0.2 2.7e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Terminase_1 PF03354.10 CEP15222.1 - 0.013 13.9 0.0 0.019 13.4 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase Myb_DNA-bind_6 PF13921.1 CEP15223.1 - 2.7e-10 40.1 2.7 2.5e-07 30.6 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP15223.1 - 1.5e-07 31.3 0.4 0.0022 18.0 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 CEP15223.1 - 0.13 12.1 0.8 0.83 9.5 0.6 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CEP15223.1 - 0.53 10.4 5.9 0.3 11.2 1.0 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase_Tyr PF07714.12 CEP15224.1 - 1e-29 103.4 0.0 1.9e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c PF02518.21 CEP15224.1 - 2.7e-27 94.6 0.1 5.3e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 CEP15224.1 - 1.5e-24 86.6 0.0 3.1e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Response_reg PF00072.19 CEP15224.1 - 2.1e-21 75.9 0.0 8.7e-21 74.0 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain Peripla_BP_4 PF13407.1 CEP15224.1 - 7.6e-18 64.7 2.0 2.8e-09 36.7 0.8 3.3 2 1 1 3 3 3 2 Periplasmic binding protein domain HisKA PF00512.20 CEP15224.1 - 4.7e-17 61.7 0.0 1.4e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GCC2_GCC3 PF07699.8 CEP15224.1 - 3.5e-05 23.3 9.4 0.00017 21.0 1.2 2.7 1 1 1 2 2 2 2 GCC2 and GCC3 NCD3G PF07562.9 CEP15224.1 - 0.0061 16.2 6.0 0.008 15.8 1.6 2.5 1 1 1 2 2 2 2 Nine Cysteines Domain of family 3 GPCR UPF0261 PF06792.6 CEP15224.1 - 0.0064 14.9 0.0 0.011 14.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) T2SF PF00482.18 CEP15224.1 - 0.07 13.0 0.2 3.8 7.4 0.0 3.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF390 PF04094.9 CEP15224.1 - 0.75 7.7 2.1 1.1 7.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Retrotrans_gag PF03732.12 CEP15225.1 - 0.0089 16.0 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein TIMELESS PF04821.9 CEP15228.1 - 4.2e-42 144.2 0.5 4.2e-42 144.2 0.3 1.8 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 CEP15228.1 - 2.5e-08 33.3 0.6 2.5e-08 33.3 0.4 2.2 2 0 0 2 2 2 2 Timeless protein C terminal region CBS PF00571.23 CEP15229.1 - 1.7e-34 117.3 7.7 1e-08 34.7 0.0 4.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 CEP15229.1 - 6e-06 25.8 0.2 1.4e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 PB1 domain MFS_1 PF07690.11 CEP15230.1 - 1.9e-37 128.8 36.5 1.9e-37 128.8 25.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily YrhC PF14143.1 CEP15230.1 - 1.7 8.6 4.3 2.7 7.9 0.6 3.0 2 0 0 2 2 2 0 YrhC-like protein zf-CCCH_2 PF14608.1 CEP15231.1 - 4.1e-13 48.7 52.0 1e-06 28.4 3.4 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Glycogen_syn PF05693.8 CEP15232.1 - 0 1073.9 0.0 0 1071.2 0.0 1.8 1 1 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CEP15232.1 - 1.6e-07 30.8 0.0 5.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CEP15232.1 - 8.8e-06 25.3 0.3 6.1e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 CEP15232.1 - 0.0052 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain cobW PF02492.14 CEP15233.1 - 7.8e-40 136.2 0.1 1.1e-39 135.6 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CEP15233.1 - 1.3e-05 24.8 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 CEP15233.1 - 0.0034 17.0 0.1 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B tRNA_anti-codon PF01336.20 CEP15233.1 - 0.0047 16.7 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CbiA PF01656.18 CEP15233.1 - 0.032 13.6 0.2 0.15 11.4 0.1 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 CEP15233.1 - 0.083 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 CEP15233.1 - 0.098 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 CEP15233.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rhomboid PF01694.17 CEP15234.1 - 1.8e-28 99.3 9.1 3.2e-28 98.5 6.3 1.3 1 0 0 1 1 1 1 Rhomboid family Glyco_transf_20 PF00982.16 CEP15235.1 - 2e-149 498.1 0.1 2.8e-149 497.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEP15235.1 - 7.7e-78 260.6 0.0 4.6e-77 258.0 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CEP15235.1 - 6.7e-07 29.1 0.0 0.00048 19.7 0.0 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CEP15235.1 - 0.011 14.9 0.0 0.044 13.0 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase PA PF02225.17 CEP15236.1 - 0.00021 20.9 0.0 0.00063 19.3 0.0 1.8 1 1 1 2 2 2 1 PA domain cobW PF02492.14 CEP15237.1 - 1.1e-45 155.2 0.5 1.6e-45 154.7 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CEP15237.1 - 2.8e-11 42.9 0.0 5.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 CEP15237.1 - 0.00019 21.2 0.1 0.00019 21.2 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 CEP15237.1 - 0.0012 18.3 0.1 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 CEP15237.1 - 0.0049 17.0 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CEP15237.1 - 0.0079 15.1 1.4 0.014 14.2 0.1 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 CEP15237.1 - 0.0086 16.0 0.0 0.045 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CEP15237.1 - 0.011 15.6 0.1 0.048 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CEP15237.1 - 0.012 15.1 0.5 0.027 14.0 0.4 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CEP15237.1 - 0.016 14.6 3.9 0.59 9.5 0.7 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 CEP15237.1 - 0.016 14.8 0.4 0.076 12.7 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CEP15237.1 - 0.017 15.3 2.9 0.018 15.3 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 CEP15237.1 - 0.033 13.9 0.0 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 CEP15237.1 - 0.043 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 CEP15237.1 - 0.044 13.3 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CEP15237.1 - 0.054 13.4 2.0 0.16 11.9 1.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 CEP15237.1 - 0.054 13.9 1.1 0.39 11.2 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein ABC_tran PF00005.22 CEP15237.1 - 0.061 13.6 0.6 0.2 11.9 0.1 2.1 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 CEP15237.1 - 3.2 8.0 8.7 1.1e+02 3.0 5.4 2.8 1 1 0 1 1 1 0 AAA domain Proteasom_Rpn13 PF04683.8 CEP15238.1 - 2.6e-19 69.0 0.9 3.4e-15 55.8 0.1 2.7 1 1 1 2 2 2 2 Proteasome complex subunit Rpn13 ubiquitin receptor RINGv PF12906.2 CEP15239.1 - 2.5e-07 30.6 9.6 4.1e-07 29.9 6.7 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 CEP15239.1 - 0.00031 20.2 5.9 0.0005 19.6 4.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CEP15239.1 - 0.00036 20.4 6.4 0.00063 19.6 4.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 CEP15239.1 - 0.00043 20.0 5.9 0.00071 19.3 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 CEP15239.1 - 0.14 11.8 0.1 0.14 11.8 0.0 1.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.20 CEP15239.1 - 2 8.1 6.0 3.4 7.3 4.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CEP15239.1 - 4.2 7.1 8.1 7.7 6.2 5.2 1.7 1 1 0 1 1 1 0 PHD-finger S1 PF00575.18 CEP15240.1 - 3.8e-12 46.1 0.0 5.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.12 CEP15240.1 - 6e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 PDDEXK_5 PF11645.3 CEP15240.1 - 0.006 16.2 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK endonuclease S-AdoMet_synt_C PF02773.11 CEP15241.1 - 3.2e-77 256.9 0.2 5.6e-77 256.1 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CEP15241.1 - 1.8e-47 160.1 0.0 4e-47 159.0 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CEP15241.1 - 2.1e-44 149.8 0.1 5.1e-44 148.5 0.1 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain SNF2_N PF00176.18 CEP15242.1 - 4.6e-71 239.0 1.1 1.1e-70 237.8 0.8 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 CEP15242.1 - 1.2e-50 171.2 22.7 1.2e-50 171.2 15.7 3.3 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 CEP15242.1 - 3.4e-13 49.2 0.0 9.1e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ras PF00071.17 CEP15243.1 - 1.4e-37 128.5 0.0 1.7e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP15243.1 - 6e-10 39.6 0.0 1.1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP15243.1 - 0.00032 19.9 0.0 0.00044 19.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP15243.1 - 0.0032 16.9 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ICL PF00463.16 CEP15244.1 - 3e-252 837.4 0.6 3.4e-252 837.3 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CEP15244.1 - 3.2e-10 39.6 0.1 6.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF1741 PF08427.5 CEP15245.1 - 5.9e-52 176.4 3.3 5.9e-52 176.4 2.3 2.5 4 0 0 4 4 4 1 Domain of unknown function (DUF1741) LRR_4 PF12799.2 CEP15246.1 - 4.6e-06 26.1 12.9 0.011 15.3 0.1 5.1 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP15246.1 - 8.4e-05 22.0 7.7 0.08 13.0 0.1 5.4 5 1 0 5 5 5 2 Leucine Rich Repeat F-box-like PF12937.2 CEP15246.1 - 0.00022 20.8 0.5 0.0016 18.1 0.2 2.5 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 CEP15246.1 - 0.00041 20.0 4.7 0.45 10.3 0.1 3.9 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CEP15246.1 - 0.00045 19.9 13.8 0.044 13.8 0.4 5.6 6 0 0 6 6 6 2 Leucine Rich repeat F-box PF00646.28 CEP15246.1 - 0.001 18.6 0.1 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain BNR_assoc_N PF14873.1 CEP15246.1 - 0.022 14.5 0.4 0.87 9.3 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of BNR-repeat neuraminidase PNK3P PF08645.6 CEP15246.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase LRR_7 PF13504.1 CEP15246.1 - 5.9 7.5 10.9 4.3 7.9 0.3 4.5 4 1 0 4 4 4 0 Leucine rich repeat Adap_comp_sub PF00928.16 CEP15247.1 - 8.9e-93 310.1 0.2 1.1e-92 309.8 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CEP15247.1 - 1.1e-10 41.3 0.4 2e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.9 CEP15247.1 - 0.0022 16.7 0.0 0.0028 16.3 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Metallophos PF00149.23 CEP15248.1 - 1.1e-11 44.5 0.5 2.6e-11 43.3 0.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP15248.1 - 4.9e-10 39.4 0.0 7.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pneumo_att_G PF05539.6 CEP15248.1 - 0.0023 17.3 1.8 0.0038 16.6 1.2 1.2 1 0 0 1 1 1 1 Pneumovirinae attachment membrane glycoprotein G dUTPase PF00692.14 CEP15249.1 - 2.4e-41 140.2 0.0 2.8e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase Lactamase_B_2 PF12706.2 CEP15250.1 - 5.4e-32 110.9 0.0 3.3e-30 105.0 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CEP15250.1 - 5.2e-18 64.2 0.0 1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CEP15250.1 - 2.4e-12 46.9 0.0 4.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ERK-JNK_inhib PF15002.1 CEP15251.1 - 0.024 13.9 1.5 0.025 13.9 1.0 1.0 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Ribosomal_L37 PF08561.5 CEP15251.1 - 0.51 9.9 3.0 0.77 9.3 2.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Reticulon PF02453.12 CEP15252.1 - 2.3e-20 72.9 4.3 3.3e-20 72.3 3.0 1.2 1 0 0 1 1 1 1 Reticulon Wzy_C PF04932.10 CEP15252.1 - 0.68 9.7 4.0 3.5 7.3 2.8 2.2 2 1 0 2 2 2 0 O-Antigen ligase Peptidase_M22 PF00814.20 CEP15254.1 - 8.2e-87 291.0 0.0 9.7e-87 290.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 CEP15254.1 - 0.051 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Cpn10 PF00166.16 CEP15255.1 - 2.4e-30 104.3 0.2 2.7e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit CHORD PF04968.7 CEP15258.1 - 2e-52 175.2 22.4 4.5e-27 94.0 4.3 2.4 2 0 0 2 2 2 2 CHORD Brix PF04427.13 CEP15258.1 - 8.9e-51 172.2 0.7 1.7e-50 171.3 0.1 1.7 2 0 0 2 2 2 1 Brix domain CS PF04969.11 CEP15258.1 - 1.9e-15 57.1 2.2 4e-15 56.1 1.5 1.6 1 0 0 1 1 1 1 CS domain Sel1 PF08238.7 CEP15261.1 - 1.4e-30 105.0 21.6 2.6e-07 31.0 0.2 7.3 7 0 0 7 7 7 6 Sel1 repeat TPR_8 PF13181.1 CEP15261.1 - 0.25 11.2 1.6 6.6 6.7 0.1 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 CEP15262.1 - 9.6e-72 241.2 0.0 1.2e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15262.1 - 5.6e-30 104.2 0.0 8.3e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP15262.1 - 5.5e-05 22.3 0.0 0.00017 20.7 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP15262.1 - 0.00035 20.3 0.0 0.00055 19.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP15262.1 - 0.0048 15.8 0.0 0.041 12.8 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CEP15262.1 - 0.046 13.0 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family UPF0113 PF03657.8 CEP15263.1 - 4.6e-10 39.3 0.0 5.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) D-ser_dehydrat PF14031.1 CEP15265.1 - 6e-18 64.8 0.0 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CEP15265.1 - 2.2e-17 63.3 0.0 3.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA-synt_1 PF00133.17 CEP15266.1 - 5.7e-177 589.3 0.0 7.2e-176 585.7 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CEP15266.1 - 1.7e-24 86.3 0.2 7.1e-18 64.8 0.0 2.6 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CEP15266.1 - 3.4e-20 72.0 5.2 1.5e-08 33.6 0.0 5.1 4 2 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CEP15266.1 - 2.2e-09 36.8 0.0 4.3e-08 32.6 0.0 2.4 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 CEP15266.1 - 1.4e-06 27.6 0.0 0.0098 15.0 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.4 CEP15266.1 - 0.0079 16.2 1.5 0.02 14.9 1.0 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 CEP15266.1 - 0.014 14.2 0.0 0.19 10.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 CEP15266.1 - 0.016 14.3 0.0 0.32 10.0 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) SR-25 PF10500.4 CEP15266.1 - 1.4 8.3 5.9 2.8 7.3 4.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_membrane PF00664.18 CEP15267.1 - 1.6e-101 339.3 21.9 7.4e-54 183.0 8.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP15267.1 - 2.4e-70 235.1 0.1 6.3e-35 120.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CEP15267.1 - 8.2e-13 48.0 7.3 2.2e-05 23.8 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CEP15267.1 - 2.5e-11 42.8 1.1 4.1e-06 25.6 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 CEP15267.1 - 1.1e-09 38.6 0.1 0.08 12.8 0.0 4.9 4 1 0 4 4 4 2 AAA domain AAA_22 PF13401.1 CEP15267.1 - 2.2e-08 34.3 1.6 0.0055 16.8 0.2 4.2 3 2 0 3 3 2 2 AAA domain DUF258 PF03193.11 CEP15267.1 - 5.5e-08 32.1 0.1 0.0017 17.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CEP15267.1 - 2e-07 31.1 5.3 0.0085 16.0 0.4 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CEP15267.1 - 6.3e-07 28.8 1.2 0.025 14.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CEP15267.1 - 1.4e-06 29.1 0.1 0.058 14.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 CEP15267.1 - 9.7e-06 25.2 1.1 0.24 10.9 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CEP15267.1 - 1.3e-05 25.0 0.0 0.25 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CEP15267.1 - 4.9e-05 23.1 4.7 0.15 11.9 0.2 3.9 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CEP15267.1 - 5.4e-05 22.3 0.2 0.025 13.6 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 CEP15267.1 - 0.00032 20.8 5.6 1.4 9.1 0.7 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CEP15267.1 - 0.00038 19.9 1.6 0.98 8.7 0.0 3.8 4 0 0 4 4 4 1 AAA-like domain AAA_18 PF13238.1 CEP15267.1 - 0.00045 20.5 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CEP15267.1 - 0.00047 19.8 0.0 0.83 9.3 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 CEP15267.1 - 0.0013 17.5 0.1 0.14 10.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 CEP15267.1 - 0.0013 18.8 0.0 4.3 7.5 0.0 3.5 3 0 0 3 3 3 1 RNA helicase SRP54 PF00448.17 CEP15267.1 - 0.0018 17.7 0.3 0.76 9.1 0.0 2.8 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 CEP15267.1 - 0.003 17.5 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CEP15267.1 - 0.0032 17.2 0.1 6.5 6.4 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CEP15267.1 - 0.004 17.0 0.0 2.2 8.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.8 CEP15267.1 - 0.015 14.2 0.0 0.36 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 CEP15267.1 - 0.034 13.5 1.1 10 5.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 CEP15267.1 - 0.064 11.9 6.7 0.9 8.1 0.0 2.6 3 0 0 3 3 2 0 G-protein alpha subunit NACHT PF05729.7 CEP15267.1 - 0.069 12.8 0.0 12 5.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 CEP15267.1 - 0.078 12.9 0.1 14 5.6 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 CEP15267.1 - 0.11 12.2 2.4 9 6.1 0.0 3.4 3 0 0 3 3 3 0 Part of AAA domain Synapsin_N PF10581.4 CEP15267.1 - 0.14 11.9 0.0 8.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Synapsin N-terminal AAA_23 PF13476.1 CEP15267.1 - 6.7 6.9 11.5 8.3 6.6 0.1 3.5 4 0 0 4 4 3 0 AAA domain Proteasome PF00227.21 CEP15269.1 - 1.3e-27 96.3 0.0 1.5e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Aldo_ket_red PF00248.16 CEP15270.1 - 2.3e-41 141.4 0.0 2.8e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cyclase_polyket PF04673.7 CEP15270.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Polyketide synthesis cyclase Acyl-CoA_dh_1 PF00441.19 CEP15271.1 - 6.8e-35 120.3 1.2 1.1e-34 119.7 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 CEP15271.1 - 8.7e-22 76.7 0.0 1.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 CEP15271.1 - 2.6e-19 68.4 0.2 5e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CEP15271.1 - 4.9e-13 49.6 0.0 2.2e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DSPc PF00782.15 CEP15272.1 - 1.3e-32 112.1 0.2 2.1e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP15272.1 - 0.00099 18.5 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF1657 PF07870.6 CEP15272.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) CDKN3 PF05706.7 CEP15272.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Yippee-Mis18 PF03226.9 CEP15272.1 - 0.17 11.9 4.2 0.75 9.8 1.8 2.6 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Glyco_trans_1_4 PF13692.1 CEP15273.1 - 2.4e-21 76.3 0.0 5.8e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CEP15273.1 - 1e-15 57.5 0.0 1.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CEP15273.1 - 9.8e-08 32.1 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CEP15273.1 - 1.8e-06 28.1 0.0 3.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Methyltransf_11 PF08241.7 CEP15274.1 - 8.7e-17 61.4 0.0 1.4e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP15274.1 - 8.8e-15 54.7 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP15274.1 - 2.1e-11 43.6 0.0 4.7e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP15274.1 - 6.2e-10 39.6 0.0 2.2e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP15274.1 - 1.3e-06 28.6 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP15274.1 - 1.7e-06 27.3 0.0 2.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CEP15274.1 - 2.4e-05 24.7 0.0 5.5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP15274.1 - 5.4e-05 22.3 0.0 0.0013 17.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 CEP15274.1 - 0.00066 19.3 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 CEP15274.1 - 0.00068 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEP15274.1 - 0.00095 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.13 CEP15274.1 - 0.0023 17.2 0.0 0.0073 15.6 0.0 1.8 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 CEP15274.1 - 0.0026 17.7 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 CEP15274.1 - 0.0064 15.7 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 CEP15274.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEP15274.1 - 0.082 12.2 0.1 0.35 10.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase small domain Sec10 PF07393.6 CEP15275.1 - 0.18 9.9 2.6 0.22 9.6 1.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Auxin_repressed PF05564.7 CEP15275.1 - 0.23 12.0 12.3 0.06 13.9 5.8 1.9 1 1 1 2 2 2 0 Dormancy/auxin associated protein Complex1_LYR_1 PF13232.1 CEP15276.1 - 6.4e-20 71.1 0.3 8.3e-20 70.7 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CEP15276.1 - 3.6e-18 65.0 0.3 7.1e-18 64.1 0.1 1.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 CEP15276.1 - 0.0095 16.3 0.1 0.011 16.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like CTNNBL PF08216.6 CEP15277.1 - 7.2e-37 125.2 2.6 7.2e-37 125.2 1.8 3.7 3 1 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Spore_YhaL PF14147.1 CEP15277.1 - 0.099 12.1 0.1 0.37 10.2 0.1 2.0 1 0 0 1 1 1 0 Sporulation protein YhaL cwf21 PF08312.7 CEP15278.1 - 5.7e-17 61.3 6.3 5.7e-17 61.3 4.3 3.5 3 1 1 4 4 4 1 cwf21 domain NUDIX PF00293.23 CEP15279.1 - 1.3e-17 63.7 0.0 2.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TFIIF_alpha PF05793.7 CEP15279.1 - 7.5e-07 27.8 30.2 1.1e-06 27.3 20.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 CEP15279.1 - 0.0042 15.6 39.3 0.0059 15.1 27.2 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 CEP15279.1 - 0.018 13.5 20.4 0.024 13.1 14.1 1.2 1 0 0 1 1 1 0 Daxx Family SOBP PF15279.1 CEP15279.1 - 0.098 13.0 27.6 0.16 12.3 19.1 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.10 CEP15279.1 - 0.45 9.0 12.2 0.64 8.5 8.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CEP15279.1 - 2.7 5.5 22.6 3.8 5.1 15.6 1.3 1 0 0 1 1 1 0 Ycf1 PAP2 PF01569.16 CEP15280.1 - 2e-26 92.1 0.6 2e-26 92.1 0.4 1.4 2 0 0 2 2 2 1 PAP2 superfamily DUF1700 PF08006.6 CEP15280.1 - 4.9 6.4 5.3 1.2 8.4 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) RELT PF12606.3 CEP15280.1 - 7.5 5.7 0.0 7.5 5.7 0.0 2.8 3 1 0 3 3 3 0 Tumour necrosis factor receptor superfamily member 19 Saccharop_dh PF03435.13 CEP15281.1 - 2.1e-22 79.6 0.0 2.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CEP15281.1 - 0.0026 17.7 0.0 0.006 16.6 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CEP15281.1 - 0.027 14.1 0.1 0.099 12.2 0.0 1.8 2 0 0 2 2 2 0 KR domain NmrA PF05368.8 CEP15281.1 - 0.039 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Peptidase_M1 PF01433.15 CEP15282.1 - 2.6e-75 253.9 0.0 3.4e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CEP15282.1 - 1.6e-43 147.7 0.1 2.6e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CEP15282.1 - 1.1e-14 54.5 0.0 2.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 CEP15282.1 - 0.027 14.4 1.2 0.23 11.4 0.9 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Prefoldin_2 PF01920.15 CEP15285.1 - 0.0042 16.8 0.5 0.0052 16.5 0.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF1664 PF07889.7 CEP15285.1 - 0.0096 15.7 0.6 0.014 15.1 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 CEP15285.1 - 0.0097 16.1 0.3 0.017 15.3 0.2 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 CEP15285.1 - 0.013 15.1 2.7 0.016 14.7 1.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ORF6C PF10552.4 CEP15285.1 - 0.023 14.4 1.3 0.029 14.0 0.3 1.7 1 1 1 2 2 2 0 ORF6C domain Dynamitin PF04912.9 CEP15285.1 - 0.029 13.1 0.6 0.037 12.8 0.4 1.4 1 1 0 1 1 1 0 Dynamitin RmuC PF02646.11 CEP15285.1 - 0.032 13.0 1.8 0.038 12.8 1.2 1.1 1 0 0 1 1 1 0 RmuC family Vps5 PF09325.5 CEP15285.1 - 0.035 13.3 0.5 0.042 13.0 0.4 1.3 1 1 0 1 1 1 0 Vps5 C terminal like Scaffolding_pro PF11418.3 CEP15285.1 - 0.038 14.3 0.7 0.058 13.7 0.5 1.3 1 0 0 1 1 1 0 Phi29 scaffolding protein Acyl-ACP_TE PF01643.12 CEP15285.1 - 0.051 12.5 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase Med4 PF10018.4 CEP15285.1 - 0.064 12.6 0.8 0.087 12.2 0.5 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Laminin_II PF06009.7 CEP15285.1 - 0.078 12.7 1.9 0.11 12.2 1.3 1.2 1 0 0 1 1 1 0 Laminin Domain II Thg1C PF14413.1 CEP15285.1 - 0.09 12.4 0.6 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Thg1 C terminal domain DivIVA PF05103.8 CEP15285.1 - 0.11 12.6 2.2 0.12 12.3 1.5 1.1 1 0 0 1 1 1 0 DivIVA protein Fib_alpha PF08702.5 CEP15285.1 - 0.14 12.2 4.2 0.36 10.9 2.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MCPsignal PF00015.16 CEP15285.1 - 0.14 11.6 3.0 0.18 11.2 2.0 1.3 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.20 CEP15285.1 - 0.29 11.3 3.1 0.43 10.7 2.2 1.4 1 1 0 1 1 1 0 Syntaxin RVP_2 PF08284.6 CEP15286.1 - 0.00013 21.9 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP15286.1 - 0.00024 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CEP15286.1 - 0.00042 20.7 0.2 0.0032 17.9 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Allexi_40kDa PF05549.6 CEP15286.1 - 0.011 15.1 3.3 0.031 13.5 2.3 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein V_ATPase_I PF01496.14 CEP15286.1 - 0.065 11.0 3.1 0.12 10.1 2.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 CEP15286.1 - 1.4 8.7 8.3 0.7 9.7 3.9 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 CEP15286.1 - 1.5 7.1 4.2 0.69 8.2 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) zf-AD PF07776.10 CEP15287.1 - 0.005 16.8 0.3 0.013 15.5 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) zf-RING_3 PF14369.1 CEP15287.1 - 0.67 9.9 3.4 1.9 8.5 2.4 1.7 1 0 0 1 1 1 0 zinc-finger zf-C2H2_4 PF13894.1 CEP15287.1 - 0.84 10.1 4.5 0.45 10.9 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Retrotrans_gag PF03732.12 CEP15288.1 - 4.8e-05 23.3 1.2 0.00012 22.0 0.2 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CEP15288.1 - 0.00014 22.2 0.5 0.00079 19.8 0.0 2.5 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.15 CEP15288.1 - 0.00025 20.9 1.7 0.00056 19.7 0.1 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 CEP15288.1 - 0.0051 16.7 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Zip PF02535.17 CEP15288.1 - 0.42 9.5 5.3 0.63 9.0 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter rve PF00665.21 CEP15289.1 - 2e-09 37.5 0.0 6.4e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP15289.1 - 3.7e-09 36.2 2.3 5.1e-09 35.8 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PSP1 PF04468.7 CEP15289.1 - 0.0058 16.5 0.0 0.92 9.5 0.0 3.0 3 0 0 3 3 3 1 PSP1 C-terminal conserved region rve_3 PF13683.1 CEP15289.1 - 0.0067 15.9 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 CEP15290.1 - 1.3e-29 102.7 0.0 2.3e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP15290.1 - 0.00071 18.7 0.1 0.0029 16.7 0.1 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP15290.1 - 0.0015 18.6 0.0 0.0047 17.0 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP15290.1 - 0.0023 17.5 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.2 CEP15290.1 - 0.0093 16.1 0.0 0.027 14.7 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.5 CEP15290.1 - 0.051 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF4551 PF15087.1 CEP15290.1 - 0.061 11.6 0.0 0.095 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) rve PF00665.21 CEP15290.1 - 0.073 13.1 0.0 0.98 9.5 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain Phage_AlpA PF05930.7 CEP15290.1 - 0.082 12.6 0.0 0.75 9.5 0.0 2.4 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_28 PF13518.1 CEP15290.1 - 0.11 12.5 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.11 CEP15290.1 - 0.15 11.5 0.0 0.44 10.1 0.0 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Aldo_ket_red PF00248.16 CEP15291.1 - 1.4e-61 207.8 0.0 1.6e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_4 PF01565.18 CEP15291.1 - 0.09 12.2 0.0 0.48 9.9 0.0 2.1 2 1 0 2 2 2 0 FAD binding domain RPN7 PF10602.4 CEP15292.1 - 5.5e-43 146.3 0.6 5.5e-43 146.3 0.4 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 CEP15292.1 - 1.7e-17 63.6 3.0 1.9e-17 63.4 0.7 2.1 2 0 0 2 2 2 1 PCI domain DUF615 PF04751.9 CEP15292.1 - 0.01 15.5 0.1 0.022 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF615) DUF3199 PF11436.3 CEP15292.1 - 0.03 14.1 0.1 0.11 12.3 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3199) DUF2063 PF09836.4 CEP15292.1 - 0.064 13.2 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) RBP_receptor PF14752.1 CEP15293.1 - 1.6e-11 43.2 13.1 4e-11 41.9 8.9 1.7 1 1 0 1 1 1 1 Retinol binding protein receptor Oest_recep PF02159.10 CEP15293.1 - 0.51 10.4 5.0 1 9.5 3.5 1.4 1 0 0 1 1 1 0 Oestrogen receptor DDE_3 PF13358.1 CEP15294.1 - 2.8e-18 66.0 0.0 4.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Cyt-b5 PF00173.23 CEP15294.1 - 9.1e-10 38.2 0.0 2.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain rve PF00665.21 CEP15294.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Cation_efflux PF01545.16 CEP15295.1 - 4.9e-45 153.7 5.3 1.7e-39 135.6 0.6 2.3 2 0 0 2 2 2 2 Cation efflux family Steroid_dh PF02544.11 CEP15296.1 - 2.2e-39 134.6 1.9 3.6e-39 133.9 1.3 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CEP15296.1 - 8.3e-07 28.5 0.3 1.6e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CEP15296.1 - 0.00015 21.8 0.8 0.00053 20.0 0.6 2.0 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 CEP15296.1 - 0.04 14.1 0.1 0.098 12.8 0.1 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Myb_DNA-binding PF00249.26 CEP15297.1 - 7.5e-33 112.3 10.7 9.9e-08 31.9 0.0 5.6 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP15297.1 - 1.2e-29 102.2 2.2 2.6e-09 37.0 0.0 4.4 4 1 1 5 5 5 4 Myb-like DNA-binding domain Tox-GHH PF15636.1 CEP15297.1 - 2.2 7.9 7.8 1.4 8.6 0.0 3.6 4 1 1 5 5 5 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin LSM PF01423.17 CEP15299.1 - 1.4e-18 66.2 0.0 1.9e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Shadoo PF14999.1 CEP15299.1 - 0.3 10.9 6.0 0.43 10.4 4.1 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Sugar_tr PF00083.19 CEP15300.1 - 2.2e-10 39.7 0.1 2.7e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3817 PF12823.2 CEP15300.1 - 0.39 11.1 2.7 0.8 10.1 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3817) Exo_endo_phos PF03372.18 CEP15301.1 - 1.3e-08 35.1 0.7 2.4e-08 34.2 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP15301.1 - 1.5e-06 27.7 0.2 7.7e-06 25.5 0.1 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase ERCC4 PF02732.10 CEP15304.1 - 1.4e-27 96.2 0.1 3.2e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 ERCC4 domain HTH_45 PF14947.1 CEP15304.1 - 0.015 15.0 0.1 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix MutL PF13941.1 CEP15304.1 - 0.02 13.2 0.0 0.036 12.3 0.0 1.3 1 0 0 1 1 1 0 MutL protein WW PF00397.21 CEP15305.1 - 0.0011 18.7 8.9 0.0011 18.7 6.2 2.5 2 0 0 2 2 2 1 WW domain Packaging_FI PF14000.1 CEP15305.1 - 9 6.5 7.4 33 4.7 0.0 2.5 2 1 0 2 2 2 0 DNA packaging protein FI Sel1 PF08238.7 CEP15306.1 - 3.3e-19 68.8 6.7 2.9e-07 30.9 2.2 4.0 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 CEP15306.1 - 0.05 13.2 5.4 0.88 9.2 0.0 2.8 3 0 0 3 3 3 0 TPR repeat Methyltransf_23 PF13489.1 CEP15307.1 - 5e-14 52.3 0.0 8.3e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP15307.1 - 4.1e-13 49.6 0.0 2e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP15307.1 - 4.2e-12 45.9 0.0 1.9e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP15307.1 - 8e-11 42.2 0.0 2.2e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP15307.1 - 4.3e-08 33.7 0.0 1.3e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP15307.1 - 5.3e-08 33.1 0.0 2.6e-07 30.9 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP15307.1 - 4.1e-05 23.5 0.0 0.00013 21.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP15307.1 - 4.2e-05 22.6 0.0 0.00028 19.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 CEP15307.1 - 4.3e-05 22.8 0.0 6.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_29 PF03141.11 CEP15307.1 - 0.00018 20.0 0.0 0.00037 18.9 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 CEP15307.1 - 0.00036 19.7 0.0 0.00082 18.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 CEP15307.1 - 0.0037 16.6 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 CEP15307.1 - 0.021 14.1 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 CEP15307.1 - 0.046 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.6 CEP15307.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) IZUMO PF15005.1 CEP15308.1 - 0.16 12.0 3.3 0.086 12.8 0.8 1.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion Phage_GP20 PF06810.6 CEP15308.1 - 0.37 10.2 11.1 0.027 13.8 3.8 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 VSG_B PF13206.1 CEP15308.1 - 1.8 7.6 8.3 0.32 10.0 1.7 2.0 2 0 0 2 2 2 0 Trypanosomal VSG domain UPF0561 PF10573.4 CEP15311.1 - 0.079 12.8 5.0 3.6 7.4 2.6 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0561 GCR1_C PF12550.3 CEP15312.1 - 6.7e-19 67.5 0.2 1.4e-18 66.4 0.2 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HD_assoc PF13286.1 CEP15312.1 - 0.0046 17.2 0.1 6.1 7.1 0.0 2.7 3 0 0 3 3 3 2 Phosphohydrolase-associated domain Snf7 PF03357.16 CEP15313.1 - 8e-29 100.1 30.9 1.6e-28 99.1 21.1 1.6 1 1 1 2 2 2 1 Snf7 GDA1_CD39 PF01150.12 CEP15313.1 - 0.011 14.2 0.8 0.014 13.9 0.5 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DUF2428 PF10350.4 CEP15313.1 - 0.019 14.0 0.2 0.024 13.6 0.1 1.4 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Ribosomal_60s PF00428.14 CEP15313.1 - 0.17 12.3 4.0 0.14 12.5 0.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2533 PF10752.4 CEP15313.1 - 3.1 8.1 7.5 2.6 8.3 0.1 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2533) V_ATPase_I PF01496.14 CEP15313.1 - 4.4 5.0 11.0 1.9 6.2 0.3 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family zf-C2H2_2 PF12756.2 CEP15314.1 - 2.8e-10 40.1 21.0 0.00022 21.2 0.1 4.6 3 2 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CEP15314.1 - 3.9e-07 30.0 51.9 0.0012 18.8 0.4 6.5 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP15314.1 - 0.00038 20.5 45.0 0.042 14.0 2.4 6.1 6 0 0 6 6 6 4 Zinc-finger of C2H2 type BSP_II PF05432.6 CEP15314.1 - 0.015 14.6 8.4 0.028 13.7 5.8 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) zf-C2H2 PF00096.21 CEP15314.1 - 0.015 15.6 2.8 0.015 15.6 1.9 6.5 6 0 0 6 6 6 0 Zinc finger, C2H2 type 3-dmu-9_3-mt PF06983.8 CEP15314.1 - 0.15 12.3 0.0 0.55 10.5 0.0 2.0 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase CENP-B_dimeris PF09026.5 CEP15314.1 - 0.78 10.0 8.7 2.4 8.4 6.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SET PF00856.23 CEP15315.1 - 5.7e-07 29.9 0.2 0.013 15.8 0.0 2.9 3 0 0 3 3 3 2 SET domain F-box-like PF12937.2 CEP15316.1 - 3e-11 42.8 0.0 7.7e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP15316.1 - 2.9e-08 33.1 0.0 1.7e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 F-box domain Nucleoplasmin PF03066.10 CEP15316.1 - 8.3 5.9 10.9 6.5 6.2 5.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin Aa_trans PF01490.13 CEP15317.1 - 1.1e-79 267.8 35.3 1.3e-79 267.5 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sec20 PF03908.8 CEP15317.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.8 1 0 0 1 1 1 0 Sec20 DUF3401 PF11881.3 CEP15317.1 - 0.22 10.9 3.3 0.16 11.3 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3401) Mito_carr PF00153.22 CEP15318.1 - 5.2e-26 90.1 6.3 5.6e-11 42.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SUR7 PF06687.7 CEP15319.1 - 3e-19 69.4 18.9 4.5e-19 68.8 13.1 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF3087 PF11286.3 CEP15319.1 - 1.1 8.4 4.2 3.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Adeno_E3_CR2 PF02439.10 CEP15319.1 - 2.8 7.5 10.7 2.6 7.6 0.1 2.8 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 zf-DHHC PF01529.15 CEP15319.1 - 3.3 7.0 8.2 4 6.7 3.0 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase Clc-like PF07062.7 CEP15319.1 - 3.6 6.7 9.6 6.8 5.8 6.7 1.5 1 1 0 1 1 1 0 Clc-like Ribonuc_red_lgC PF02867.10 CEP15320.1 - 3.9e-183 609.8 0.0 5.1e-183 609.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CEP15320.1 - 1.3e-16 60.1 0.1 3.6e-16 58.7 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CEP15320.1 - 5.1e-12 46.0 3.3 1.9e-11 44.2 0.0 3.3 4 0 0 4 4 4 1 ATP cone domain F-box-like PF12937.2 CEP15321.1 - 1.5e-05 24.6 0.0 6.2e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP15321.1 - 1.5e-05 24.5 0.8 3.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 F-box domain Herpes_DNAp_acc PF04929.7 CEP15321.1 - 0.021 13.7 0.4 0.033 13.1 0.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MFS_1 PF07690.11 CEP15322.1 - 2.3e-52 177.8 34.2 2.3e-52 177.8 23.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP15322.1 - 5.3e-12 45.0 32.6 3.4e-10 39.0 22.6 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 CEP15322.1 - 0.014 13.5 0.3 0.014 13.5 0.2 2.0 3 0 0 3 3 3 0 Transmembrane secretion effector Herpes_US9 PF06072.6 CEP15322.1 - 2.7 7.8 6.9 1.1 9.1 0.8 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF1625 PF07787.7 CEP15322.1 - 6.4 5.9 5.8 18 4.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1625) TRM13 PF05206.9 CEP15323.1 - 2e-59 200.9 8.1 3.3e-59 200.2 5.6 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 Ribosomal_S2 PF00318.15 CEP15324.1 - 1.9e-42 144.8 0.3 1.3e-20 73.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 E1-E2_ATPase PF00122.15 CEP15325.1 - 1.1e-15 57.2 2.6 5.6e-15 55.0 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEP15325.1 - 1.6e-12 48.3 0.1 3.4e-09 37.4 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP15325.1 - 2.8e-12 47.1 0.4 7.9e-11 42.4 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP15325.1 - 4.3e-11 42.6 0.0 2e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEP15325.1 - 0.0066 16.0 3.3 0.0085 15.6 0.1 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 CEP15325.1 - 0.076 11.8 0.4 0.36 9.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) F-box PF00646.28 CEP15326.1 - 0.00063 19.3 0.1 0.0017 17.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEP15326.1 - 0.0029 17.2 0.2 0.0055 16.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like DASH_Dad1 PF08649.5 CEP15327.1 - 1.8e-10 40.3 0.9 2.6e-10 39.8 0.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad1 FlaF PF07309.6 CEP15327.1 - 0.077 12.8 0.3 0.097 12.5 0.2 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF GCN5L1 PF06320.8 CEP15327.1 - 0.14 11.9 0.2 0.14 11.9 0.1 1.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Brevenin PF03032.10 CEP15327.1 - 4.1 7.3 7.9 0.43 10.4 2.4 1.7 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family SpoIIE PF07228.7 CEP15328.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CEP15328.1 - 2.8e-07 30.1 1.2 1.9e-06 27.4 0.8 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CEP15328.1 - 0.00023 20.6 1.1 0.23 10.8 0.0 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C MFS_1 PF07690.11 CEP15329.1 - 7.7e-32 110.3 29.5 7.7e-32 110.3 20.5 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily MgtE PF01769.11 CEP15330.1 - 4.7e-31 107.8 26.8 8.4e-19 68.1 1.0 4.3 2 1 2 4 4 4 2 Divalent cation transporter CRT-like PF08627.5 CEP15330.1 - 0.12 12.3 1.2 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 CRT-like ECH_C PF13766.1 CEP15331.1 - 2.8e-31 108.1 0.5 8e-31 106.6 0.1 1.9 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CEP15331.1 - 1.7e-23 83.0 0.0 5.8e-23 81.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Mt_ATP-synt_B PF05405.9 CEP15331.1 - 0.013 15.0 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RF-1 PF00472.15 CEP15332.1 - 2.5e-24 85.2 0.7 2.5e-24 85.2 0.5 2.1 2 0 0 2 2 2 1 RF-1 domain DnaJ PF00226.26 CEP15332.1 - 1.3e-17 63.2 0.3 1.3e-17 63.2 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain zf-CSL PF05207.8 CEP15332.1 - 7.3e-09 35.0 0.3 1.5e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 CSL zinc finger HTH_28 PF13518.1 CEP15333.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CTP_transf_2 PF01467.21 CEP15337.1 - 6.1e-23 81.6 0.1 1.9e-22 80.0 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase CybS PF05328.7 CEP15338.1 - 2.9e-33 114.2 0.3 3.5e-33 114.0 0.2 1.0 1 0 0 1 1 1 1 CybS DASH_Dad1 PF08649.5 CEP15339.1 - 2e-13 49.8 0.1 2.5e-13 49.4 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 FlaG PF03646.10 CEP15339.1 - 0.00061 19.9 0.2 0.00079 19.5 0.1 1.2 1 0 0 1 1 1 1 FlaG protein PilJ PF13675.1 CEP15339.1 - 0.0029 17.9 1.1 0.0032 17.7 0.8 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term Peptidase_M26_C PF07580.9 CEP15339.1 - 0.0077 14.5 0.3 0.008 14.5 0.2 1.0 1 0 0 1 1 1 1 M26 IgA1-specific Metallo-endopeptidase C-terminal region EMP24_GP25L PF01105.19 CEP15339.1 - 0.019 14.7 0.3 0.021 14.5 0.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DASH_Dad4 PF08650.5 CEP15339.1 - 0.04 13.8 0.2 0.05 13.5 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 T4SS PF07996.6 CEP15339.1 - 0.067 13.0 1.2 0.072 12.9 0.8 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins EAP30 PF04157.11 CEP15339.1 - 0.1 11.7 0.5 0.1 11.7 0.4 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family HR1 PF02185.11 CEP15339.1 - 0.12 12.0 2.6 0.2 11.4 1.8 1.3 1 0 0 1 1 1 0 Hr1 repeat SPA PF08616.5 CEP15340.1 - 2.5e-36 123.7 0.0 4.9e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 CEP15340.1 - 1.3e-23 83.6 0.2 1.3e-23 83.6 0.2 2.3 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 CEP15340.1 - 1.7e-08 33.3 9.0 0.00018 20.0 0.0 4.2 2 1 1 3 3 3 2 Transport protein Avl9 Pex14_N PF04695.8 CEP15340.1 - 0.0062 16.5 10.6 0.016 15.2 7.3 1.7 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CEP15340.1 - 0.011 14.0 22.8 0.017 13.3 15.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CEP15340.1 - 0.062 13.0 5.4 0.11 12.2 3.7 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA MRF_C2 PF13888.1 CEP15340.1 - 0.11 12.2 3.4 0.26 11.0 2.3 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 CD20 PF04103.10 CEP15340.1 - 0.13 12.2 0.7 0.25 11.2 0.5 1.4 1 0 0 1 1 1 0 CD20-like family FimP PF09766.4 CEP15340.1 - 0.18 10.8 13.7 0.31 10.0 9.5 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF3337 PF11816.3 CEP15340.1 - 0.31 10.3 7.5 0.03 13.7 2.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) Gag_spuma PF03276.9 CEP15340.1 - 0.79 7.9 17.3 1.2 7.3 12.0 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Serinc PF03348.10 CEP15340.1 - 2.2 6.8 6.1 3.3 6.3 4.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.12 CEP15340.1 - 5.3 5.7 5.8 9.5 4.9 4.0 1.3 1 0 0 1 1 1 0 Presenilin FlaG PF03646.10 CEP15340.1 - 8.5 6.5 20.0 32 4.7 12.3 2.6 2 0 0 2 2 2 0 FlaG protein Skp1 PF01466.14 CEP15341.1 - 2.2e-38 130.1 2.1 4e-38 129.3 1.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CEP15341.1 - 5.2e-27 93.7 1.0 1e-26 92.7 0.3 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CofC PF01983.11 CEP15341.1 - 0.03 13.2 1.1 0.039 12.9 0.7 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like ATP_bind_1 PF03029.12 CEP15342.1 - 6.1e-74 248.5 1.1 9.3e-74 247.9 0.7 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CEP15342.1 - 8.6e-07 28.5 0.4 2.7e-05 23.6 0.3 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 CEP15342.1 - 1.9e-05 24.2 0.1 5.9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 CEP15342.1 - 7.4e-05 22.8 0.0 0.00071 19.6 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CEP15342.1 - 0.00013 22.0 0.0 0.00056 20.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 CEP15342.1 - 0.0002 20.7 0.0 0.005 16.1 0.0 2.8 2 1 1 3 3 3 1 Ferrous iron transport protein B AAA_33 PF13671.1 CEP15342.1 - 0.00022 21.1 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.15 CEP15342.1 - 0.00032 19.4 6.9 0.0054 15.4 0.0 2.9 2 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CEP15342.1 - 0.00034 20.5 0.0 0.00094 19.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 CEP15342.1 - 0.00049 19.5 0.2 0.0092 15.4 0.1 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CEP15342.1 - 0.00059 18.7 0.1 0.58 8.8 0.0 2.2 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 CEP15342.1 - 0.00097 19.9 1.4 0.0034 18.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CEP15342.1 - 0.0013 18.2 0.1 0.098 12.1 0.0 3.0 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CEP15342.1 - 0.0015 18.2 0.0 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 CEP15342.1 - 0.0022 16.8 1.8 0.009 14.9 0.0 2.5 2 1 0 2 2 2 1 NB-ARC domain Arf PF00025.16 CEP15342.1 - 0.0031 16.7 1.3 0.51 9.5 0.0 3.1 3 2 0 3 3 3 1 ADP-ribosylation factor family MobB PF03205.9 CEP15342.1 - 0.0032 17.1 0.0 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CEP15342.1 - 0.0042 16.5 0.0 0.027 13.9 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 CEP15342.1 - 0.012 15.1 0.0 0.05 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain CBP4 PF07960.6 CEP15342.1 - 0.013 15.0 1.2 0.028 14.0 0.8 1.5 1 0 0 1 1 1 0 CBP4 Arch_ATPase PF01637.13 CEP15342.1 - 0.019 14.6 1.8 0.099 12.3 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CEP15342.1 - 0.024 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 CEP15342.1 - 0.027 14.0 0.0 0.088 12.3 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 CEP15342.1 - 0.037 13.0 0.5 0.36 9.7 0.4 2.5 1 1 0 1 1 1 0 KAP family P-loop domain Thymidylate_kin PF02223.12 CEP15342.1 - 0.045 13.1 0.6 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase APS_kinase PF01583.15 CEP15342.1 - 0.05 13.2 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase UPF0079 PF02367.12 CEP15342.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 CEP15342.1 - 0.071 13.0 0.2 0.49 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CEP15342.1 - 0.093 12.2 1.8 0.3 10.6 1.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CEP15342.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 CEP15342.1 - 0.28 11.4 4.4 0.29 11.4 0.0 2.8 3 1 0 3 3 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CEP15342.1 - 0.31 10.5 1.9 0.34 10.3 0.0 1.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family PP2C_C PF07830.8 CEP15342.1 - 0.31 11.1 1.6 0.87 9.7 1.1 1.7 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain SRPRB PF09439.5 CEP15342.1 - 0.34 10.0 3.8 1.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Miro PF08477.8 CEP15342.1 - 0.56 10.7 2.9 11 6.4 0.0 3.1 2 1 0 3 3 3 0 Miro-like protein CENP-B_dimeris PF09026.5 CEP15342.1 - 1 9.6 9.6 2.4 8.4 6.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_23 PF13476.1 CEP15342.1 - 1.2 9.3 7.2 33 4.7 5.0 2.4 1 1 0 1 1 1 0 AAA domain Aldedh PF00171.17 CEP15343.1 - 9.8e-179 594.5 0.0 1.1e-178 594.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CEP15343.1 - 0.043 13.0 0.0 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) PALP PF00291.20 CEP15344.1 - 4.4e-55 187.0 0.3 8e-55 186.2 0.2 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 CEP15344.1 - 0.001 18.4 0.0 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain IER PF05760.7 CEP15344.1 - 4.8 7.0 8.8 7.9 6.3 6.1 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) FancD2 PF14631.1 CEP15345.1 - 1.6e-159 532.5 44.8 6e-148 494.2 12.9 5.4 2 1 2 4 4 4 3 Fanconi anaemia protein FancD2 nuclease HLH PF00010.21 CEP15346.1 - 8.5e-19 67.0 1.7 3.9e-18 64.8 0.1 3.0 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain rve PF00665.21 CEP15347.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 CEP15350.1 - 1.3e-09 37.9 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 CEP15350.1 - 6.1e-06 26.0 0.0 7.1e-05 22.5 0.1 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease Filament PF00038.16 CEP15351.1 - 0.0061 16.0 12.3 0.0061 16.0 8.5 3.7 2 1 2 4 4 4 3 Intermediate filament protein Zn_clus PF00172.13 CEP15352.1 - 5e-08 32.7 7.8 1e-07 31.7 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CEP15352.1 - 2.2e-07 30.0 1.5 3.8e-07 29.2 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.17 CEP15353.1 - 1.1e-12 47.3 0.0 1.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP15353.1 - 1.2e-10 41.0 0.0 2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP15353.1 - 1.2e-09 37.9 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP15353.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PPR_3 PF13812.1 CEP15353.1 - 0.13 12.6 0.0 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Ank_5 PF13857.1 CEP15353.1 - 0.13 12.5 0.5 1.4 9.2 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) NUDIX PF00293.23 CEP15354.1 - 4.8e-16 58.6 0.0 7.1e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 CEP15354.1 - 0.0066 15.8 0.3 0.013 14.9 0.2 1.5 1 1 0 1 1 1 1 NUDIX domain zf-RING_2 PF13639.1 CEP15355.1 - 9.3e-08 31.7 5.4 3.2e-07 30.0 3.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP15355.1 - 4.7e-06 26.6 0.9 1.2e-05 25.3 0.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP15355.1 - 6.8e-05 22.4 3.8 0.00019 20.9 2.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP15355.1 - 7.2e-05 22.4 3.8 0.00019 21.0 2.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CEP15355.1 - 0.00012 22.0 2.0 0.00037 20.4 1.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEP15355.1 - 0.00046 19.9 1.2 0.0013 18.5 0.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CEP15355.1 - 0.0048 16.3 0.9 0.01 15.3 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CEP15355.1 - 0.028 14.1 0.4 0.028 14.1 0.3 2.0 2 0 0 2 2 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CEP15355.1 - 0.028 14.0 4.0 0.079 12.6 2.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CEP15355.1 - 0.063 13.3 1.5 0.18 11.8 1.0 1.8 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 CEP15355.1 - 0.12 12.2 3.8 1.3 9.0 2.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Arrestin_N PF00339.24 CEP15356.1 - 6.1e-11 42.3 0.2 1.2e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP15356.1 - 0.0034 17.4 0.0 0.0096 16.0 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.20 CEP15357.1 - 4.5e-69 232.4 0.0 6.7e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15357.1 - 8.9e-35 119.9 0.0 1.4e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15357.1 - 6.4e-05 22.0 0.0 0.00013 21.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Glyco_hydro_32N PF00251.15 CEP15357.1 - 0.024 14.0 2.6 0.13 11.5 1.8 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain MAPEG PF01124.13 CEP15358.1 - 3.3e-05 23.4 1.6 4.2e-05 23.1 1.1 1.2 1 0 0 1 1 1 1 MAPEG family DUF2142 PF09913.4 CEP15358.1 - 0.0012 17.6 7.5 0.0014 17.3 5.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) FixP_N PF14715.1 CEP15358.1 - 0.1 11.9 0.3 0.1 11.9 0.2 2.7 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF3302 PF11742.3 CEP15358.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3302) Glucan_synthase PF02364.10 CEP15359.1 - 0 1155.2 3.9 0 1155.2 2.7 2.2 2 1 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CEP15359.1 - 2.7e-29 101.4 0.0 8.2e-29 99.8 0.0 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 GPI-anchored PF10342.4 CEP15360.1 - 4.6e-10 39.8 3.0 4.6e-10 39.8 2.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_S9 PF00380.14 CEP15361.1 - 5.5e-37 126.6 0.1 6.3e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L18e PF00828.14 CEP15362.1 - 5.9e-32 110.7 1.4 8.7e-32 110.2 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 eIF-6 PF01912.13 CEP15363.1 - 2e-86 288.1 0.7 3.1e-86 287.5 0.5 1.3 1 0 0 1 1 1 1 eIF-6 family DnaJ PF00226.26 CEP15364.1 - 5.6e-13 48.4 3.7 1.5e-09 37.4 2.0 3.6 2 1 0 2 2 2 2 DnaJ domain RRM_6 PF14259.1 CEP15364.1 - 0.0017 18.3 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1510 PF07423.6 CEP15364.1 - 0.011 15.0 5.3 0.023 14.0 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRM_1 PF00076.17 CEP15364.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 CEP15365.1 - 1.1e-05 23.5 0.0 1.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP15365.1 - 0.061 11.9 0.0 0.33 9.4 0.0 2.1 3 0 0 3 3 3 0 MreB/Mbl protein HSP70 PF00012.15 CEP15366.1 - 0.001 17.1 0.0 0.023 12.5 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CEP15366.1 - 0.0039 15.8 0.0 0.015 13.9 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Herpes_TK_C PF08465.5 CEP15366.1 - 0.06 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal GCR1_C PF12550.3 CEP15368.1 - 1e-09 38.1 0.2 1.5e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Pyr_redox_2 PF07992.9 CEP15370.1 - 1.3e-26 93.7 0.0 8.2e-18 65.0 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP15370.1 - 2.1e-12 47.2 0.0 4.1e-11 43.1 0.0 2.8 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP15370.1 - 3.3e-07 30.5 0.1 0.02 14.9 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEP15370.1 - 0.018 13.5 0.5 0.17 10.3 0.0 2.2 1 1 1 2 2 2 0 HI0933-like protein TPPII_N PF12583.3 CEP15370.1 - 0.019 15.0 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal NAD_binding_9 PF13454.1 CEP15370.1 - 0.063 13.0 1.6 8.9 6.0 0.1 3.2 2 1 0 3 3 3 0 FAD-NAD(P)-binding Reo_sigmaC PF04582.7 CEP15371.1 - 0.022 13.9 8.2 0.018 14.2 1.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 CEP15371.1 - 0.053 12.7 10.0 0.05 12.7 1.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 CEP15371.1 - 0.074 12.9 9.7 0.035 13.9 1.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 CEP15371.1 - 0.1 12.4 8.5 0.033 13.9 3.1 2.1 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF3166 PF11365.3 CEP15371.1 - 0.11 12.9 1.7 0.49 10.8 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) DUF972 PF06156.8 CEP15371.1 - 0.13 12.6 9.1 1.6 9.0 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2408 PF10303.4 CEP15371.1 - 0.13 12.3 7.3 1.5 8.9 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF948 PF06103.6 CEP15371.1 - 0.14 12.0 3.7 0.66 9.8 0.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 CEP15371.1 - 0.3 9.7 12.9 0.082 11.5 3.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ATP-synt_B PF00430.13 CEP15371.1 - 0.32 10.8 6.2 2.7 7.8 0.1 2.6 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) Atg14 PF10186.4 CEP15371.1 - 0.33 9.8 12.5 0.55 9.1 1.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 CEP15371.1 - 0.46 10.2 9.6 1.3 8.8 5.5 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Rho_Binding PF08912.6 CEP15371.1 - 0.69 10.2 6.0 4.2 7.7 0.1 2.8 2 1 0 2 2 2 0 Rho Binding DUF904 PF06005.7 CEP15371.1 - 0.77 10.0 6.4 2.9 8.2 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Fzo_mitofusin PF04799.8 CEP15371.1 - 0.84 9.0 7.3 0.31 10.4 1.5 2.2 2 0 0 2 2 2 0 fzo-like conserved region Cortex-I_coil PF09304.5 CEP15371.1 - 0.85 9.6 8.4 2 8.5 0.2 2.5 1 1 0 2 2 2 0 Cortexillin I, coiled coil COG2 PF06148.6 CEP15371.1 - 0.97 9.3 7.3 2.4 8.0 1.0 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 CEP15371.1 - 1.2 8.9 11.5 5.8 6.7 0.3 2.3 1 1 1 2 2 2 0 Tropomyosin like Nsp1_C PF05064.8 CEP15371.1 - 1.9 8.1 8.1 0.58 9.8 0.6 2.4 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF2638 PF10937.3 CEP15372.1 - 6e-14 53.0 2.1 4.1e-08 34.2 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2638) Ribonuc_L-PSP PF01042.16 CEP15373.1 - 1.3e-29 102.4 0.1 1.6e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cyt-b5 PF00173.23 CEP15374.1 - 5.2e-17 61.4 0.6 2.1e-16 59.4 0.0 2.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 CEP15374.1 - 6.9e-17 61.7 21.9 6.9e-17 61.7 15.2 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF2385 PF09539.5 CEP15375.1 - 0.17 12.2 4.9 64 4.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2385) SOBP PF15279.1 CEP15375.1 - 0.27 11.5 6.6 0.51 10.6 1.4 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein DUF1451 PF07295.6 CEP15375.1 - 3.1 7.5 9.3 9.7 5.9 0.0 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1451) PEX11 PF05648.9 CEP15377.1 - 2.9e-55 186.9 0.6 3.2e-55 186.8 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ribosomal_L14e PF01929.12 CEP15378.1 - 1.2e-25 89.6 5.8 2e-25 88.8 4.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CEP15378.1 - 0.00093 18.8 0.2 0.0015 18.1 0.1 1.3 1 0 0 1 1 1 1 KOW motif U6-snRNA_bdg PF10596.4 CEP15378.1 - 0.059 12.7 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 UCH PF00443.24 CEP15379.1 - 1.6e-82 276.6 9.2 4.6e-82 275.1 2.5 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP15379.1 - 1.2e-20 74.1 12.1 2.7e-13 50.0 0.0 3.5 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CEP15379.1 - 3e-12 46.8 0.0 3e-12 46.8 0.0 3.1 3 0 0 3 3 3 1 DUSP domain USP7_C2 PF14533.1 CEP15379.1 - 0.00015 21.2 0.1 0.00015 21.2 0.1 2.6 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal tRNA-Thr_ED PF08915.6 CEP15379.1 - 0.13 12.2 2.0 0.48 10.4 1.4 2.0 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase HECT PF00632.20 CEP15380.1 - 4e-80 269.3 0.0 9.3e-80 268.1 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) BUD22 PF09073.5 CEP15380.1 - 9.8e-06 24.8 15.9 9.8e-06 24.8 11.0 3.8 3 1 0 3 3 3 1 BUD22 Daxx PF03344.10 CEP15380.1 - 0.00012 20.6 30.4 0.00012 20.6 21.1 3.9 3 1 0 3 3 3 2 Daxx Family MDM31_MDM32 PF08118.6 CEP15381.1 - 4.7e-77 259.5 0.1 3.3e-76 256.7 0.0 2.0 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Metallophos PF00149.23 CEP15381.1 - 7.2e-19 67.9 0.0 7.4e-13 48.3 0.1 2.5 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase RVT_1 PF00078.22 CEP15385.1 - 3.3e-29 101.7 0.0 6.4e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP15385.1 - 7.1e-05 23.0 0.4 0.0002 21.5 0.3 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Terminase_5 PF06056.7 CEP15386.1 - 0.0045 16.4 0.1 0.0099 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.1 CEP15386.1 - 0.011 15.3 0.0 0.047 13.3 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF4508 PF14969.1 CEP15386.1 - 0.037 14.0 0.5 0.037 14.0 0.3 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4508) HTH_28 PF13518.1 CEP15386.1 - 0.038 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NTR PF01759.16 CEP15386.1 - 0.044 13.3 0.8 6 6.4 0.0 2.5 2 1 0 2 2 2 0 UNC-6/NTR/C345C module HTH_29 PF13551.1 CEP15386.1 - 0.048 13.8 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.1 CEP15386.1 - 0.13 13.0 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Retrotrans_gag PF03732.12 CEP15387.1 - 0.014 15.4 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.22 CEP15388.1 - 1.2e-11 44.3 0.1 2.7e-11 43.2 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PerC PF06069.6 CEP15390.1 - 0.047 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 PerC transcriptional activator Lipase_3 PF01764.20 CEP15391.1 - 1.7e-18 66.5 0.0 3.1e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CEP15391.1 - 0.0099 15.6 0.0 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEP15391.1 - 0.014 15.0 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Tubulin PF00091.20 CEP15391.1 - 0.059 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Nuc_sug_transp PF04142.10 CEP15392.1 - 1.2e-77 260.2 26.4 9.6e-45 152.5 1.8 2.6 3 0 0 3 3 3 2 Nucleotide-sugar transporter EamA PF00892.15 CEP15392.1 - 1.8e-07 31.2 3.9 1.8e-07 31.2 2.7 3.4 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 CEP15392.1 - 7e-07 29.4 2.6 7e-07 29.4 1.8 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 CEP15392.1 - 3.7e-05 22.8 15.4 0.0011 17.9 0.4 2.4 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.11 CEP15392.1 - 0.00015 21.4 5.2 0.00015 21.4 3.6 3.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family Peptidase_S41 PF03572.13 CEP15393.1 - 2.8e-08 33.3 0.0 6.3e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Luteo_coat PF00894.13 CEP15393.1 - 0.036 13.8 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 Luteovirus coat protein DUF2348 PF09807.4 CEP15394.1 - 7.5e-41 139.8 0.1 9.3e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 CEP15394.1 - 4.4e-06 25.9 0.0 5.8e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 KaiC Elong_Iki1 PF10483.4 CEP15394.1 - 0.0001 21.7 0.6 0.0013 18.1 0.4 2.1 1 1 0 1 1 1 1 Elongator subunit Iki1 DUF835 PF05763.7 CEP15394.1 - 0.0031 17.0 0.3 0.017 14.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF835) AAA_25 PF13481.1 CEP15394.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2070 PF09843.4 CEP15395.1 - 0.0024 17.3 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Flavi_NS1 PF00948.16 CEP15395.1 - 0.0053 15.2 0.9 0.0064 14.9 0.6 1.1 1 0 0 1 1 1 1 Flavivirus non-structural Protein NS1 Euplotes_phero PF05842.6 CEP15395.1 - 0.1 12.9 0.5 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Histone PF00125.19 CEP15396.1 - 9.3e-32 108.9 0.4 1.4e-31 108.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEP15396.1 - 7.3e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CEP15396.1 - 0.0015 18.5 0.1 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CEP15396.1 - 0.0035 17.0 0.1 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 CEP15396.1 - 0.14 11.3 1.3 0.29 10.3 0.9 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T AA_kinase PF00696.23 CEP15397.1 - 7.6e-32 110.7 0.1 1.3e-31 110.0 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 CEP15397.1 - 8.7e-15 53.9 1.6 2.6e-10 39.6 0.2 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 CEP15397.1 - 7.3e-14 50.8 1.6 2.8e-06 26.6 0.0 3.0 3 0 0 3 3 3 2 ACT domain PseudoU_synth_1 PF01416.15 CEP15398.1 - 2.4e-16 60.0 0.0 4.3e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sas10 PF09368.5 CEP15399.1 - 9.7e-29 99.3 8.6 2.9e-28 97.8 4.7 2.6 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CEP15399.1 - 3.4e-13 49.5 0.6 2.5e-12 46.8 0.0 2.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Bud13 PF09736.4 CEP15400.1 - 2.6e-44 151.0 10.6 2.6e-44 151.0 7.3 3.0 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex INCENP_ARK-bind PF03941.10 CEP15400.1 - 4 7.3 6.9 0.26 11.1 0.2 2.4 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Homeobox PF00046.24 CEP15401.1 - 7.9e-16 57.4 1.7 1.1e-15 57.0 0.6 1.6 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CEP15401.1 - 0.0035 16.9 0.4 0.0086 15.7 0.0 1.8 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.1 CEP15401.1 - 0.028 14.0 0.1 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain G_glu_transpept PF01019.16 CEP15402.1 - 6.1e-168 559.4 0.0 7e-168 559.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.13 CEP15402.1 - 0.0052 15.5 0.2 1.1 7.8 0.1 2.2 2 0 0 2 2 2 2 Asparaginase DUF2740 PF10872.3 CEP15403.1 - 0.13 11.9 0.3 0.36 10.5 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2740) Ribosomal_L11_N PF03946.9 CEP15404.1 - 2.7e-18 65.1 0.1 4.6e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CEP15404.1 - 7.5e-12 45.2 0.1 1.3e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain LsmAD PF06741.8 CEP15405.1 - 2.4e-25 88.4 0.3 2.4e-25 88.4 0.2 2.2 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 CEP15405.1 - 1.4e-16 60.2 0.0 4e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain BIR PF00653.16 CEP15406.1 - 6.2e-28 97.0 4.2 1.2e-13 51.2 0.4 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain EamA PF00892.15 CEP15406.1 - 1.1e-23 83.5 26.2 2e-14 53.7 7.8 2.8 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CEP15406.1 - 0.0003 20.9 8.6 0.0003 20.9 6.0 3.5 2 2 1 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CEP15406.1 - 0.0029 16.7 0.1 0.0051 15.9 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter zf-C3HC PF07967.8 CEP15406.1 - 0.013 15.2 0.6 0.098 12.4 0.1 2.4 2 1 0 2 2 2 0 C3HC zinc finger-like LysM PF01476.15 CEP15407.1 - 2.3e-11 43.4 0.1 3.6e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 LysM domain Dicty_REP PF05086.7 CEP15407.1 - 0.0011 16.8 17.7 0.0014 16.4 12.2 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein PIH1 PF08190.7 CEP15407.1 - 0.028 13.8 9.3 0.037 13.4 6.5 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 TT_ORF1 PF02956.9 CEP15407.1 - 0.077 11.4 10.8 0.097 11.1 7.5 1.2 1 0 0 1 1 1 0 TT viral orf 1 Otopetrin PF03189.8 CEP15407.1 - 0.3 10.0 4.6 0.36 9.7 3.2 1.1 1 0 0 1 1 1 0 Otopetrin MAP65_ASE1 PF03999.7 CEP15407.1 - 1.2 7.6 15.3 1.4 7.4 10.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DNA_pol_viral_N PF00242.12 CEP15407.1 - 3.1 6.7 14.7 4.7 6.1 10.2 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DDHD PF02862.12 CEP15407.1 - 4.1 7.1 8.8 6 6.5 6.1 1.2 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.3 CEP15407.1 - 5.7 5.4 8.2 7.9 4.9 5.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PP_M1 PF03012.9 CEP15407.1 - 7.5 5.8 8.1 12 5.1 5.6 1.4 1 0 0 1 1 1 0 Phosphoprotein zf-CCHC_2 PF13696.1 CEP15408.1 - 0.076 12.5 0.6 0.17 11.3 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.7 CEP15409.1 - 0.16 11.8 0.3 0.29 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RVT_1 PF00078.22 CEP15411.1 - 4.4e-05 22.9 0.0 5.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP15412.1 - 8.3e-19 67.8 0.1 4.9e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CEP15412.1 - 1.3e-14 54.0 0.0 3.8e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CEP15412.1 - 0.032 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain AAA PF00004.24 CEP15413.1 - 9.9e-42 142.2 0.0 2.5e-41 140.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP15413.1 - 5.6e-06 26.5 0.0 0.0005 20.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEP15413.1 - 6.5e-06 25.9 0.1 4.9e-05 23.0 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP15413.1 - 9.3e-05 22.4 0.0 0.00024 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 CEP15413.1 - 0.00018 21.4 0.0 0.00069 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CEP15413.1 - 0.00044 19.2 0.0 0.00078 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CEP15413.1 - 0.0016 19.2 0.2 0.0048 17.7 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CEP15413.1 - 0.0032 17.2 0.1 0.0069 16.1 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CEP15413.1 - 0.0032 16.5 0.0 0.0065 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 CEP15413.1 - 0.0037 16.9 0.3 5.2 6.7 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 CEP15413.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CEP15413.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CEP15413.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEP15413.1 - 0.015 15.1 0.1 0.036 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 CEP15413.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 CEP15413.1 - 0.025 14.1 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CEP15413.1 - 0.026 14.6 0.0 0.079 13.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.12 CEP15413.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 CEP15413.1 - 0.033 14.4 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CEP15413.1 - 0.038 12.7 0.0 0.078 11.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CEP15413.1 - 0.051 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CEP15413.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CEP15413.1 - 0.081 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 CEP15413.1 - 0.09 11.8 0.1 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 CEP15413.1 - 0.13 11.6 0.2 0.5 9.7 0.0 1.9 1 1 0 2 2 2 0 AAA domain rve PF00665.21 CEP15415.1 - 2.7e-13 50.0 0.0 8.9e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP15415.1 - 0.00091 18.7 0.0 0.0035 16.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.6 CEP15415.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Helitron_like_N PF14214.1 CEP15416.1 - 1.9e-10 40.7 0.0 3.2e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4004 PF13171.1 CEP15416.1 - 0.03 14.4 0.1 0.092 12.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4004) Tail_P2_I PF09684.5 CEP15416.1 - 0.14 11.6 1.2 0.31 10.5 0.4 1.8 1 1 1 2 2 2 0 Phage tail protein (Tail_P2_I) OppC_N PF12911.2 CEP15417.1 - 0.05 12.9 0.2 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C rve PF00665.21 CEP15421.1 - 7.6e-19 67.9 0.0 2e-18 66.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Peptidase_A17 PF05380.8 CEP15422.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.5 2 0 0 2 2 2 0 Pao retrotransposon peptidase WD40 PF00400.27 CEP15423.1 - 1.3e-60 199.2 23.3 5.1e-12 45.1 0.0 9.2 9 1 0 9 9 9 7 WD domain, G-beta repeat LisH PF08513.6 CEP15423.1 - 1.6e-07 30.8 0.2 3e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 CEP15423.1 - 2.3e-07 30.7 1.2 0.057 13.1 0.1 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CEP15423.1 - 0.014 14.8 0.0 2.7 7.5 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S64 PF08192.6 CEP15423.1 - 0.031 12.6 6.3 0.042 12.1 4.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Atg14 PF10186.4 CEP15424.1 - 8.8e-26 90.5 4.9 8.8e-26 90.5 3.4 2.1 2 1 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 NQRA PF05896.6 CEP15424.1 - 0.006 15.8 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2547 PF10818.3 CEP15424.1 - 4.7 7.8 15.9 6.3 7.5 4.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Sel1 PF08238.7 CEP15425.1 - 2.2e-28 98.0 26.9 1.7e-07 31.6 1.1 5.6 6 0 0 6 6 6 5 Sel1 repeat DUF4142 PF13628.1 CEP15425.1 - 0.052 13.5 0.2 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) FYRN PF05964.9 CEP15426.1 - 1.4e-17 62.9 1.0 1.4e-17 62.9 0.7 2.1 2 0 0 2 2 2 1 F/Y-rich N-terminus FYRC PF05965.9 CEP15426.1 - 1.5e-14 53.5 0.0 4.9e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus Glycos_transf_1 PF00534.15 CEP15428.1 - 6.2e-30 103.8 0.0 3.6e-29 101.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CEP15428.1 - 1.2e-13 51.3 0.0 5e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CEP15428.1 - 4.1e-11 42.9 0.0 7.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CEP15428.1 - 1.9e-10 41.1 0.0 3.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CEP15428.1 - 1.9e-05 24.8 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CEP15428.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Acetyltransf_9 PF13527.1 CEP15428.1 - 0.15 11.9 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Reprolysin_4 PF13583.1 CEP15429.1 - 5.2e-32 111.0 4.1 1.7e-24 86.4 0.2 2.5 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CEP15429.1 - 1.3e-30 106.8 0.7 1.3e-30 106.8 0.5 3.6 4 0 0 4 4 4 2 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CEP15429.1 - 3.6e-28 98.7 5.5 2.5e-20 73.2 0.2 2.7 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CEP15429.1 - 1.5e-17 64.2 0.6 1.3e-16 61.2 0.0 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CEP15429.1 - 5.8e-17 61.6 25.2 5.8e-17 61.6 17.4 4.4 3 1 1 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 CEP15429.1 - 3.1e-06 27.0 0.1 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide SR-25 PF10500.4 CEP15429.1 - 0.1 12.0 12.4 0.081 12.3 2.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Biopterin_H PF00351.16 CEP15430.1 - 2.8e-163 542.4 0.0 3.5e-163 542.0 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 CEP15430.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 CEP15430.1 - 0.074 13.3 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 ACT domain MFS_1 PF07690.11 CEP15431.1 - 1.7e-40 138.8 42.7 4.2e-40 137.5 29.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP15431.1 - 7.5e-14 51.1 19.7 7.5e-14 51.1 13.7 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CEP15431.1 - 2.9e-10 38.9 20.7 3.8e-10 38.5 14.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CBM_21 PF03370.8 CEP15432.1 - 1.5e-27 95.7 5.0 9.6e-27 93.2 0.9 2.5 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CEP15432.1 - 0.0054 16.7 1.1 0.014 15.4 0.3 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain (family 25) Consortin_C PF15281.1 CEP15432.1 - 0.18 11.2 0.6 0.44 10.0 0.4 1.6 1 0 0 1 1 1 0 Consortin C-terminus Homeobox_KN PF05920.6 CEP15433.1 - 1.2e-16 60.0 2.3 1.2e-16 60.0 1.6 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CEP15433.1 - 7.2e-06 25.5 2.5 1.1e-05 24.9 0.6 2.1 2 0 0 2 2 2 1 Homeobox domain Daxx PF03344.10 CEP15433.1 - 0.00059 18.4 6.6 0.00069 18.2 4.6 1.3 1 0 0 1 1 1 1 Daxx Family Myc_N PF01056.13 CEP15433.1 - 0.0053 15.9 7.4 0.008 15.3 5.2 1.3 1 0 0 1 1 1 1 Myc amino-terminal region DUF2890 PF11081.3 CEP15433.1 - 0.0069 16.4 10.6 0.011 15.7 7.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) RRN3 PF05327.6 CEP15433.1 - 0.011 13.8 2.2 0.018 13.1 1.6 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GAGA_bind PF06217.7 CEP15433.1 - 0.014 15.3 4.6 0.019 14.9 3.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.7 CEP15433.1 - 0.016 13.1 9.2 0.025 12.5 6.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CEP15433.1 - 0.024 12.6 7.7 0.028 12.4 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 CEP15433.1 - 0.04 13.4 6.5 0.077 12.5 4.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Merozoite_SPAM PF07133.6 CEP15433.1 - 0.056 13.3 13.6 0.092 12.6 9.4 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) alpha-hel2 PF14456.1 CEP15433.1 - 0.4 9.3 7.5 0.65 8.7 5.2 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 Pox_RNA_Pol_19 PF05320.7 CEP15433.1 - 0.48 10.1 9.0 1 9.0 6.2 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PAXIP1_C PF15364.1 CEP15433.1 - 0.5 10.2 11.7 0.032 14.1 4.5 1.7 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein HTH_29 PF13551.1 CEP15433.1 - 0.79 9.8 4.7 0.24 11.5 0.2 2.3 2 1 1 3 3 2 0 Winged helix-turn helix Tom37_C PF11801.3 CEP15433.1 - 1.3 8.8 5.2 2.4 8.0 3.6 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain FAM176 PF14851.1 CEP15433.1 - 3.6 7.2 10.7 6.2 6.4 7.4 1.4 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.8 CEP15433.1 - 3.9 6.1 15.5 14 4.3 10.8 1.6 2 0 0 2 2 2 0 Paf1 DUF3381 PF11861.3 CEP15433.1 - 7.7 5.9 14.4 19 4.7 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) NT5C PF06941.7 CEP15434.1 - 3e-12 46.4 0.6 3e-12 46.4 0.4 1.7 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 CEP15434.1 - 0.0038 17.4 0.5 0.0038 17.4 0.3 1.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Nucleoplasmin PF03066.10 CEP15434.1 - 0.0071 15.8 1.2 0.013 15.0 0.8 1.5 1 0 0 1 1 1 1 Nucleoplasmin E2_bind PF08825.5 CEP15434.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 E2 binding domain PBP1_TM PF14812.1 CEP15434.1 - 0.48 10.7 3.6 1.5 9.1 2.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 CEP15435.1 - 2.7e-71 239.7 0.0 5e-71 238.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15435.1 - 7e-38 130.1 0.0 1.3e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CEP15435.1 - 1.1e-08 34.3 0.0 2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 CEP15435.1 - 1.5e-05 24.1 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP15435.1 - 0.008 15.9 1.0 0.036 13.8 0.3 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CEP15435.1 - 0.014 14.5 0.1 0.028 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CEP15435.1 - 0.02 14.2 0.1 0.045 13.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family ThiF PF00899.16 CEP15436.1 - 9.9e-33 112.8 0.6 2e-32 111.8 0.1 1.7 2 0 0 2 2 2 1 ThiF family Saccharop_dh PF03435.13 CEP15436.1 - 1.5e-08 34.0 0.6 2.6e-08 33.2 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 CEP15436.1 - 0.00022 20.2 0.1 0.00032 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 CEP15436.1 - 0.0013 18.2 0.1 0.0032 16.8 0.1 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CEP15436.1 - 0.01 15.4 0.0 0.035 13.7 0.0 2.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CEP15436.1 - 0.019 15.0 0.9 0.031 14.3 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CEP15436.1 - 0.041 12.9 0.2 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.12 CEP15436.1 - 0.056 13.8 0.7 0.42 11.0 0.1 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 CEP15436.1 - 0.21 11.5 2.1 1.5 8.8 0.0 2.8 2 1 0 3 3 3 0 TrkA-N domain PX PF00787.19 CEP15437.1 - 4.8e-23 81.1 0.2 1.3e-22 79.7 0.2 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CEP15437.1 - 5.9e-09 35.5 2.2 0.00025 20.3 0.5 2.3 2 0 0 2 2 2 2 Vps5 C terminal like DUF2155 PF09923.4 CEP15437.1 - 0.0069 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2155) Peptidase_C10 PF01640.12 CEP15437.1 - 0.0071 16.1 0.7 0.013 15.2 0.2 1.7 1 1 0 1 1 1 1 Peptidase C10 family DUF3510 PF12022.3 CEP15437.1 - 0.017 15.2 1.2 0.043 13.9 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) BLOC1_2 PF10046.4 CEP15437.1 - 0.032 14.3 3.9 6.1 7.0 0.4 3.4 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4611 PF15387.1 CEP15437.1 - 0.041 14.0 1.8 0.085 13.0 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PRAP PF15314.1 CEP15437.1 - 0.083 13.1 1.3 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine Halogen_Hydrol PF10112.4 CEP15437.1 - 1.4 8.3 6.6 9.6 5.5 0.5 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1451 PF07295.6 CEP15437.1 - 1.4 8.6 5.7 1.2 8.9 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1451) MFS_1 PF07690.11 CEP15438.1 - 5e-36 124.1 35.9 5.8e-36 123.9 23.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CEP15438.1 - 0.0016 18.4 1.3 0.0016 18.4 0.9 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) PRMT5 PF05185.11 CEP15439.1 - 2.2e-170 567.4 0.0 3e-170 566.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Hydrolase_like2 PF13246.1 CEP15440.1 - 1.2e-14 54.0 0.1 1.2e-13 50.7 0.0 2.5 2 1 1 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 CEP15440.1 - 4.9e-13 48.6 0.0 4.9e-13 48.6 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CEP15440.1 - 2.7e-12 47.5 1.2 5.2e-07 30.3 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP15440.1 - 2.3e-11 44.1 0.1 4.6e-10 39.9 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP15440.1 - 0.00049 19.7 0.3 0.0038 16.8 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP15440.1 - 0.03 14.5 0.0 0.083 13.1 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3712 PF12505.3 CEP15441.1 - 2.4e-27 95.4 0.1 4.7e-16 58.9 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) DUF4366 PF14283.1 CEP15442.1 - 0.001 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF1771 PF08590.5 CEP15443.1 - 1.5e-21 76.1 6.3 3.4e-21 74.9 4.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 CEP15443.1 - 1.5e-13 50.6 0.0 4e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain TLD PF07534.11 CEP15443.1 - 0.12 12.3 1.3 0.27 11.2 0.2 2.0 2 1 0 2 2 2 0 TLD Asn_synthase PF00733.16 CEP15444.1 - 3.4e-50 170.9 0.0 5.1e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CEP15444.1 - 4.2e-40 136.3 0.0 7.2e-40 135.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CEP15444.1 - 6.4e-34 116.7 0.0 1.3e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CEP15444.1 - 2.7e-05 23.0 0.0 0.58 8.8 0.0 3.2 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 CEP15444.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein 2-oxoacid_dh PF00198.18 CEP15445.1 - 8.3e-76 254.2 0.1 1.3e-75 253.6 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 CEP15445.1 - 1e-17 63.4 0.4 1.8e-17 62.7 0.3 1.4 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 CEP15445.1 - 5.6e-17 61.1 0.0 1.1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Proteasom_Rpn13 PF04683.8 CEP15446.1 - 1.2e-23 82.9 0.6 2.3e-23 82.0 0.4 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Mucin PF01456.12 CEP15446.1 - 0.00014 21.6 18.3 0.00022 20.9 12.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3595 PF12166.3 CEP15446.1 - 0.041 12.7 1.9 0.059 12.1 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) CHAD PF05235.9 CEP15446.1 - 0.12 11.9 0.1 0.24 10.9 0.1 1.5 1 1 0 1 1 1 0 CHAD domain DUF2890 PF11081.3 CEP15446.1 - 9.5 6.2 12.2 8.6 6.3 7.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) Cu-oxidase_3 PF07732.10 CEP15447.1 - 9.6e-35 118.8 1.3 9.6e-35 118.8 0.9 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CEP15447.1 - 2.5e-26 91.8 9.5 2.1e-25 88.8 0.5 4.1 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 CEP15447.1 - 3.5e-26 92.0 2.6 3.8e-26 91.9 0.1 2.4 3 0 0 3 3 3 1 Multicopper oxidase GRP PF07172.6 CEP15447.1 - 1.2 9.6 38.1 10 6.7 27.1 2.1 2 0 0 2 2 2 0 Glycine rich protein family Pkinase PF00069.20 CEP15448.1 - 1.5e-33 116.0 0.0 2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15448.1 - 1.4e-10 40.6 0.0 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_S1 PF05827.7 CEP15449.1 - 0.0071 15.6 0.5 0.04 13.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) CDC50 PF03381.10 CEP15450.1 - 5.5e-88 294.7 0.1 8e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ATG27 PF09451.5 CEP15450.1 - 1.3e-36 126.2 2.0 3.7e-22 78.8 0.5 2.2 2 0 0 2 2 2 2 Autophagy-related protein 27 Man-6-P_recep PF02157.10 CEP15450.1 - 5.3e-05 22.3 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor SSURE PF11966.3 CEP15450.1 - 0.12 11.9 0.5 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Fibronectin-binding repeat DUF706 PF05153.10 CEP15451.1 - 1.3e-109 365.3 6.3 1.7e-109 364.9 4.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 CEP15451.1 - 0.0031 17.5 0.1 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 HD domain p450 PF00067.17 CEP15452.1 - 1.5e-49 168.7 0.8 9.1e-49 166.2 0.6 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF424 PF04242.8 CEP15452.1 - 0.01 15.8 0.3 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF424) Mito_carr PF00153.22 CEP15454.1 - 1.5e-46 156.0 0.2 1.1e-24 85.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF500 PF04366.7 CEP15455.1 - 2.9e-44 149.5 0.3 5.8e-44 148.5 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_9 PF14604.1 CEP15455.1 - 3.3e-15 55.4 0.1 6e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP15455.1 - 5.1e-13 48.1 0.1 1.3e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CEP15455.1 - 6.9e-11 41.4 0.0 1.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.3 CEP15455.1 - 0.12 11.7 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) PAT1 PF09770.4 CEP15455.1 - 3.4 5.7 11.0 4.1 5.5 7.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDE_3 PF13358.1 CEP15456.1 - 2.4e-19 69.5 0.6 3.8e-19 68.8 0.4 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP15456.1 - 2.4e-16 59.5 0.7 5.5e-16 58.3 0.5 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP15456.1 - 6e-10 39.2 0.6 1.2e-09 38.3 0.2 1.7 2 0 0 2 2 1 1 Winged helix-turn helix TrmB PF01978.14 CEP15456.1 - 7.4e-05 22.3 0.2 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.1 CEP15456.1 - 0.00012 21.5 0.0 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP15456.1 - 0.00016 22.3 1.7 0.00045 20.9 1.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP15456.1 - 0.00047 20.0 0.2 0.013 15.4 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 CEP15456.1 - 0.0006 19.1 0.1 0.076 12.4 0.0 2.9 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.10 CEP15456.1 - 0.0011 18.7 1.2 0.051 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 CEP15456.1 - 0.0013 18.3 0.4 0.18 11.5 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain KorB PF08535.5 CEP15456.1 - 0.0013 18.8 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 KorB domain LacI PF00356.16 CEP15456.1 - 0.0032 17.0 0.2 0.21 11.2 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.5 CEP15456.1 - 0.025 14.1 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_17 PF12728.2 CEP15456.1 - 0.037 14.2 0.0 15 5.9 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.2 CEP15456.1 - 0.067 13.2 1.1 13 5.9 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain Mor PF08765.6 CEP15456.1 - 0.09 12.5 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_1 PF11427.3 CEP15456.1 - 0.11 12.1 0.1 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Tc3 transposase NSP2_assoc PF14758.1 CEP15457.1 - 0.064 13.3 0.5 0.064 13.3 0.3 1.8 2 0 0 2 2 2 0 Non-essential region of nsp2 of arterivirus polyprotein Metallophos PF00149.23 CEP15459.1 - 1.1e-21 77.2 1.2 1.1e-13 51.0 0.1 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase ETF PF01012.16 CEP15464.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Asp PF00026.18 CEP15466.1 - 1.7e-54 185.2 0.3 2.1e-54 184.9 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP15466.1 - 5.3e-07 29.7 0.0 1.8e-05 24.7 0.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEP15466.1 - 0.011 16.1 0.0 3 8.4 0.0 2.8 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.1 CEP15466.1 - 0.061 12.8 0.0 0.35 10.4 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal GATA PF00320.22 CEP15467.1 - 1.5e-16 59.4 2.6 1.5e-16 59.4 1.8 1.9 2 0 0 2 2 2 1 GATA zinc finger Claudin_2 PF13903.1 CEP15467.1 - 0.023 14.4 0.1 0.89 9.2 0.3 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TF_Zn_Ribbon PF08271.7 CEP15467.1 - 0.084 12.2 2.7 0.16 11.2 1.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Peptidase_S10 PF00450.17 CEP15468.1 - 4e-118 395.1 4.7 4e-118 395.1 3.3 1.6 2 0 0 2 2 2 1 Serine carboxypeptidase HD PF01966.17 CEP15468.1 - 7e-13 48.6 0.1 1.7e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 HD domain Abhydrolase_6 PF12697.2 CEP15468.1 - 0.09 12.6 0.0 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pkinase PF00069.20 CEP15469.1 - 1.8e-63 214.1 1.0 2.7e-63 213.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15469.1 - 2.8e-41 141.2 0.0 5.5e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP15469.1 - 8.9e-05 21.6 0.3 0.0002 20.5 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP15469.1 - 0.0053 16.5 2.9 1.3 8.7 0.2 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family BP28CT PF08146.7 CEP15470.1 - 0.066 12.9 2.0 0.59 9.8 0.2 2.4 1 1 1 2 2 2 0 BP28CT (NUC211) domain DUF3713 PF12506.3 CEP15470.1 - 0.52 10.4 5.9 0.35 10.9 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) LRR_4 PF12799.2 CEP15471.1 - 0.11 12.1 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Dicty_REP PF05086.7 CEP15473.1 - 0.022 12.5 4.3 0.039 11.7 3.0 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1192 PF06698.6 CEP15473.1 - 0.057 13.2 2.2 0.14 11.9 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) UvrD_C_2 PF13538.1 CEP15476.1 - 1e-05 25.5 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEP15476.1 - 0.00027 18.8 0.0 0.00033 18.5 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 CEP15476.1 - 0.0039 16.2 0.1 0.0052 15.7 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase DUF2824 PF11039.3 CEP15476.1 - 0.047 13.4 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) DDE_Tnp_1_7 PF13843.1 CEP15479.1 - 8.3e-20 71.1 0.0 1.5e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.16 CEP15479.1 - 0.0077 15.7 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Transposase DDE domain HALZ PF02183.13 CEP15480.1 - 0.067 12.9 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Med3 PF11593.3 CEP15480.1 - 1.4 8.0 17.8 1.6 7.8 12.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AA_permease PF00324.16 CEP15481.1 - 2.7e-122 408.5 45.9 3.3e-122 408.2 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEP15481.1 - 7.3e-47 159.8 47.2 9.7e-47 159.4 32.7 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1418 PF07214.7 CEP15481.1 - 0.36 10.4 2.7 1 9.0 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DUF4481 PF14800.1 CEP15481.1 - 2.5 6.9 5.9 4 6.2 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Xpo1 PF08389.7 CEP15482.1 - 3.3e-28 98.4 0.7 2.8e-27 95.4 0.1 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 CEP15482.1 - 1.9e-09 37.3 1.1 6.5e-07 29.1 0.1 2.8 2 0 0 2 2 2 2 Importin-beta N-terminal domain Mito_carr PF00153.22 CEP15483.1 - 5.4e-61 202.3 1.0 1.6e-19 69.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.3 CEP15483.1 - 0.011 15.4 0.6 3 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) UQ_con PF00179.21 CEP15484.1 - 9.5e-32 109.3 0.1 1.7e-31 108.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme ATP-synt_ab PF00006.20 CEP15485.1 - 7e-114 378.6 0.0 1.1e-113 378.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEP15485.1 - 6.6e-25 87.7 0.2 1.1e-24 87.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEP15485.1 - 2e-13 50.3 4.8 2.5e-13 49.9 1.3 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain Polyketide_cyc2 PF10604.4 CEP15486.1 - 0.0083 16.2 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport LEA_2 PF03168.8 CEP15487.1 - 0.13 12.6 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF2897 PF11446.3 CEP15487.1 - 0.17 11.7 2.3 0.37 10.6 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) OppC_N PF12911.2 CEP15487.1 - 9.8 5.6 8.6 0.39 10.1 1.0 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ApbA PF02558.11 CEP15488.1 - 1.2e-26 92.9 0.0 2e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CEP15488.1 - 8.4e-26 90.4 0.4 1.3e-25 89.7 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 CEP15488.1 - 0.0003 20.5 0.0 0.0047 16.6 0.0 2.5 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 CEP15488.1 - 0.00082 19.7 0.0 0.017 15.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CEP15488.1 - 0.026 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Na_sulph_symp PF00939.14 CEP15489.1 - 5.5e-100 335.4 26.5 6.3e-100 335.2 18.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region DUF1985 PF09331.6 CEP15489.1 - 0.11 12.2 0.1 0.36 10.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1985) Pkinase PF00069.20 CEP15490.1 - 1.2e-72 244.2 0.0 2.8e-72 242.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15490.1 - 3.4e-43 147.5 0.0 1e-42 146.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP15490.1 - 3.9e-06 26.7 0.0 0.0056 16.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP15490.1 - 0.00011 21.2 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP15490.1 - 0.00017 20.7 0.1 0.0004 19.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 CEP15490.1 - 0.004 16.3 0.0 0.0083 15.3 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase YrbL-PhoP_reg PF10707.4 CEP15490.1 - 0.032 13.5 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ketoacyl-synt_C PF02801.17 CEP15491.1 - 1.8e-36 124.5 0.3 2.6e-36 124.0 0.2 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 CEP15491.1 - 9.7e-13 48.1 0.4 3.7e-12 46.2 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.13 CEP15491.1 - 0.00058 19.2 0.2 0.0051 16.2 0.1 2.3 3 0 0 3 3 3 1 Thiolase, C-terminal domain Haem_oxygenas_2 PF14518.1 CEP15491.1 - 0.047 13.8 0.0 3.1 8.0 0.0 2.7 3 0 0 3 3 3 0 Iron-containing redox enzyme ketoacyl-synt PF00109.21 CEP15492.1 - 7.3e-10 38.7 0.0 7.5e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.20 CEP15493.1 - 1.5e-44 152.0 1.6 7.9e-44 149.7 1.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15493.1 - 3.4e-22 78.7 4.1 5.6e-21 74.7 0.6 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CEP15493.1 - 0.0012 17.9 0.9 0.0026 16.8 0.1 1.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Bac_surface_Ag PF01103.18 CEP15494.1 - 8.9e-44 150.2 2.6 1.3e-43 149.6 1.8 1.3 1 0 0 1 1 1 1 Surface antigen AAA_assoc PF14363.1 CEP15494.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA HMGL-like PF00682.14 CEP15496.1 - 4.4e-70 236.0 0.1 6.5e-70 235.4 0.1 1.3 1 0 0 1 1 1 1 HMGL-like UvrD_C PF13361.1 CEP15496.1 - 0.00086 18.8 0.1 0.65 9.3 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain CAP PF00188.21 CEP15497.1 - 1.3e-20 74.0 3.8 1.8e-20 73.6 2.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PXA PF02194.10 CEP15498.1 - 1.1e-25 90.3 0.9 2.9e-25 88.9 0.6 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 CEP15498.1 - 1.7e-16 60.2 1.0 6.3e-16 58.4 0.4 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CEP15498.1 - 0.0015 18.3 0.0 0.0048 16.6 0.0 1.9 1 0 0 1 1 1 1 PX domain Kei1 PF08552.6 CEP15499.1 - 1.3e-22 80.3 19.9 9.5e-18 64.5 7.4 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 DUF308 PF03729.8 CEP15499.1 - 0.16 12.0 12.5 1.2 9.1 3.4 2.4 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF4131 PF13567.1 CEP15499.1 - 0.67 9.3 5.3 0.5 9.7 2.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DmsC PF04976.7 CEP15499.1 - 1.5 7.9 9.6 22 4.1 0.0 2.3 2 0 0 2 2 2 0 DMSO reductase anchor subunit (DmsC) AMP-binding PF00501.23 CEP15500.1 - 4.8e-74 249.2 0.0 6.9e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CEP15500.1 - 6.6e-70 234.8 0.0 9.9e-70 234.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CEP15500.1 - 6.6e-14 51.9 0.1 4.1e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 CEP15500.1 - 3e-11 43.2 0.0 7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 CEP15500.1 - 1.1e-10 42.3 0.0 4.1e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CEP15500.1 - 5.9e-08 31.7 0.0 1.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 CEP15500.1 - 2.1e-05 23.5 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 CEP15500.1 - 0.0048 16.8 1.2 0.079 12.8 0.1 3.1 3 1 0 3 3 3 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CEP15500.1 - 0.018 15.0 0.0 0.71 9.8 0.0 2.5 1 1 0 1 1 1 0 NADH(P)-binding HxxPF_rpt PF13745.1 CEP15500.1 - 0.073 13.3 0.0 0.33 11.2 0.0 2.1 1 1 0 1 1 1 0 HxxPF-repeated domain Tap-RNA_bind PF09162.5 CEP15501.1 - 0.05 13.1 0.4 0.11 12.0 0.2 1.7 1 1 0 1 1 1 0 Tap, RNA-binding DUF21 PF01595.15 CEP15501.1 - 0.12 11.7 0.2 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF21 DUF21 PF01595.15 CEP15502.1 - 0.072 12.3 0.4 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF21 SNARE_assoc PF09335.6 CEP15502.1 - 0.093 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein Ribosomal_S19 PF00203.16 CEP15503.1 - 2.4e-14 52.6 0.1 4.6e-14 51.7 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S19 Steroid_dh PF02544.11 CEP15504.1 - 3.3e-19 69.1 1.9 5.5e-19 68.4 1.3 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2407_C PF13373.1 CEP15504.1 - 1.3e-13 51.0 0.1 2.5e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.18 CEP15504.1 - 1e-11 44.0 0.1 1.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 CEP15504.1 - 7.7e-08 32.4 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEP15504.1 - 1.6e-07 31.1 0.0 8.3e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 CEP15504.1 - 3.7e-05 23.3 0.0 6.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like VHS PF00790.14 CEP15505.1 - 9.5e-37 125.7 1.9 7.2e-31 106.7 0.0 3.2 2 2 1 4 4 4 2 VHS domain Alpha_adaptinC2 PF02883.15 CEP15505.1 - 5.3e-18 65.4 0.3 1.3e-17 64.1 0.2 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 CEP15505.1 - 1.2e-13 50.9 3.4 1.2e-13 50.8 0.7 2.2 2 0 0 2 2 2 1 GAT domain Nucleoporin_FG PF13634.1 CEP15505.1 - 0.2 11.8 8.7 0.36 11.0 6.1 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region Aldedh PF00171.17 CEP15506.1 - 2.9e-133 444.5 0.0 3.4e-133 444.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CEP15506.1 - 0.025 13.3 0.3 0.045 12.4 0.0 1.5 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) RCR PF12273.3 CEP15507.1 - 0.011 16.2 0.7 0.022 15.3 0.0 1.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF1180 PF06679.7 CEP15507.1 - 0.048 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Orthopox_A36R PF05950.6 CEP15507.1 - 0.63 9.9 4.1 3.9 7.3 0.3 2.3 2 0 0 2 2 2 0 Orthopoxvirus A36R protein SR-25 PF10500.4 CEP15507.1 - 0.73 9.2 4.0 1 8.7 2.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4171 PF13775.1 CEP15507.1 - 1 9.5 6.3 1.3 9.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) Ribosomal_S4e PF00900.15 CEP15508.1 - 3.8e-32 109.7 1.5 1.3e-31 108.1 0.3 2.2 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CEP15508.1 - 1.4e-15 56.8 1.2 5.2e-15 55.0 1.1 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 CEP15508.1 - 6.1e-06 25.5 0.1 1.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CEP15508.1 - 0.00045 19.8 3.5 0.00045 19.8 2.4 3.4 4 1 0 4 4 4 1 KOW motif Ins134_P3_kin PF05770.6 CEP15509.1 - 3e-46 157.8 2.1 3.9e-46 157.4 1.5 1.1 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase ATP-grasp_4 PF13535.1 CEP15509.1 - 0.00029 20.6 0.0 0.0014 18.4 0.0 1.9 1 1 1 2 2 2 1 ATP-grasp domain SNARE PF05739.14 CEP15509.1 - 0.037 13.7 0.3 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 SNARE domain Neural_ProG_Cyt PF06567.6 CEP15510.1 - 0.16 12.1 1.9 4.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Pkinase PF00069.20 CEP15511.1 - 7.2e-71 238.3 0.0 1e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15511.1 - 7.1e-48 162.9 0.0 1.1e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CEP15511.1 - 1e-22 80.3 0.2 1.1e-21 76.9 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CEP15511.1 - 2e-07 30.2 0.0 3.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 CEP15511.1 - 0.039 13.1 0.1 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.18 CEP15511.1 - 0.04 13.6 3.2 0.23 11.1 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 CEP15512.1 - 1.2e-31 109.9 0.0 1.5e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEP15512.1 - 1.1e-25 90.1 0.0 2.7e-25 88.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 CEP15512.1 - 9.9e-05 22.3 0.0 0.0002 21.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP15512.1 - 0.026 13.7 0.0 0.06 12.5 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 CEP15512.1 - 0.036 12.7 0.0 2.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family SIS PF01380.17 CEP15513.1 - 3.3e-22 78.4 0.0 6.7e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 SIS domain CBS PF00571.23 CEP15513.1 - 1.2e-08 34.5 2.3 0.00019 21.1 0.0 4.1 4 0 0 4 4 4 2 CBS domain SIS_2 PF13580.1 CEP15513.1 - 5.5e-08 32.6 0.0 0.00082 19.0 0.0 2.6 1 1 1 2 2 2 2 SIS domain ORC4_C PF14629.1 CEP15514.1 - 4.7e-42 143.6 0.0 8.3e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CEP15514.1 - 6.7e-20 71.8 0.1 1.8e-19 70.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CEP15514.1 - 1e-09 38.6 0.0 2.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CEP15514.1 - 4.1e-08 32.4 0.0 6.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 CEP15514.1 - 6.9e-08 32.7 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CEP15514.1 - 4.9e-07 29.5 0.1 9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 CEP15514.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 CEP15514.1 - 0.00098 19.0 0.3 0.0043 16.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain MobB PF03205.9 CEP15514.1 - 0.0037 16.9 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CEP15514.1 - 0.0043 16.9 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 CEP15514.1 - 0.0048 15.9 0.0 0.0077 15.2 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_29 PF13555.1 CEP15514.1 - 0.0066 15.9 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CEP15514.1 - 0.0075 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 CEP15514.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 CEP15514.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 CEP15514.1 - 0.016 14.0 0.1 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 CEP15514.1 - 0.028 14.8 0.0 0.08 13.4 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 CEP15514.1 - 0.029 13.8 0.0 0.4 10.0 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 CEP15514.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 CEP15514.1 - 0.034 13.6 0.2 4.3 6.8 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 CEP15514.1 - 0.04 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.4 CEP15514.1 - 0.044 12.7 0.3 1.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF258 PF03193.11 CEP15514.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 CEP15514.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CEP15514.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DrsE PF02635.10 CEP15515.1 - 0.013 15.5 0.2 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 DsrE/DsrF-like family DUF4078 PF13300.1 CEP15515.1 - 0.16 12.1 7.4 0.2 11.8 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) YlqD PF11068.3 CEP15515.1 - 0.22 11.5 7.9 0.28 11.2 5.4 1.2 1 0 0 1 1 1 0 YlqD protein Ax_dynein_light PF10211.4 CEP15515.1 - 0.54 10.0 9.7 0.57 10.0 6.7 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain CPSF100_C PF13299.1 CEP15515.1 - 1.3 9.1 4.5 1.4 9.0 3.1 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_delta_4 PF04081.8 CEP15516.1 - 4.3e-21 75.4 0.5 5e-21 75.2 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Vhr1 PF04001.8 CEP15516.1 - 0.049 13.5 2.7 0.13 12.2 1.9 1.7 1 1 0 1 1 1 0 Transcription factor Vhr1 Gastrin PF00918.12 CEP15516.1 - 0.45 11.3 2.9 0.67 10.7 2.0 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Lipase_GDSL PF00657.17 CEP15517.1 - 6.8e-14 52.2 0.7 8.1e-14 52.0 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP15517.1 - 6.6e-07 29.6 0.1 1.1e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PRNT PF15174.1 CEP15517.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Prion-related protein testis-specific ApoLp-III PF07464.6 CEP15517.1 - 1.6 8.7 4.0 0.45 10.5 0.3 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Ricin_B_lectin PF00652.17 CEP15518.1 - 1.1e-15 57.7 1.9 1.3e-07 31.6 0.7 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP15518.1 - 1.1e-15 57.8 3.9 2.9e-11 43.6 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Pep3_Vps18 PF05131.9 CEP15519.1 - 3.3e-45 153.1 0.2 1.2e-44 151.2 0.1 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CEP15519.1 - 6e-12 45.3 17.5 3.7e-10 39.5 3.5 4.2 4 2 1 5 5 5 2 Region in Clathrin and VPS Vps39_2 PF10367.4 CEP15519.1 - 0.0019 18.3 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 CEP15519.1 - 0.026 14.2 3.6 0.069 12.8 2.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CEP15519.1 - 0.12 12.2 8.5 0.016 15.0 2.6 2.1 2 0 0 2 2 2 0 Ring finger domain UPRTase PF14681.1 CEP15520.1 - 5.8e-79 264.1 0.0 6.9e-79 263.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CEP15520.1 - 5.5e-05 22.8 0.0 8.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.20 CEP15524.1 - 2.1e-45 154.8 0.0 2.1e-45 154.8 0.0 2.5 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15524.1 - 1.3e-20 73.5 0.0 1.3e-19 70.2 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15524.1 - 8.6e-10 38.0 0.0 1.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SSXT PF05030.7 CEP15524.1 - 0.055 13.0 6.2 0.56 9.8 1.0 2.8 2 0 0 2 2 2 0 SSXT protein (N-terminal region) TPR_MLP1_2 PF07926.7 CEP15524.1 - 0.81 9.4 64.0 0.0079 15.9 12.8 5.4 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 CEP15525.1 - 1.2e-76 257.2 0.0 1.4e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15525.1 - 1.1e-37 129.5 0.0 1.4e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15525.1 - 1.6e-05 24.0 0.0 6.1e-05 22.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CEP15525.1 - 0.0026 16.8 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP15525.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CEP15525.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL bZIP_2 PF07716.10 CEP15526.1 - 1.2e-08 34.6 19.0 1.6e-08 34.2 10.9 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 CEP15526.1 - 5.6e-08 32.6 15.9 1.7e-07 31.0 10.4 2.2 1 1 1 2 2 2 2 bZIP transcription factor CCDC155 PF14662.1 CEP15526.1 - 5.2e-05 22.9 6.4 5.2e-05 22.9 4.5 1.6 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 bZIP_Maf PF03131.12 CEP15526.1 - 0.0034 17.6 12.6 0.0098 16.1 8.6 2.0 1 1 0 1 1 1 1 bZIP Maf transcription factor TPR_MLP1_2 PF07926.7 CEP15526.1 - 0.0058 16.3 14.5 0.018 14.7 10.0 1.9 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4618 PF15397.1 CEP15526.1 - 0.0066 15.8 6.3 0.0092 15.3 4.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) APG6 PF04111.7 CEP15526.1 - 0.016 14.2 9.9 0.02 13.9 6.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CEP15526.1 - 0.026 14.0 4.6 0.026 14.0 3.2 2.8 1 1 1 2 2 2 0 Septum formation initiator Myosin_tail_1 PF01576.14 CEP15526.1 - 0.037 11.7 16.4 0.049 11.3 11.4 1.1 1 0 0 1 1 1 0 Myosin tail NPV_P10 PF05531.7 CEP15526.1 - 0.06 13.5 0.8 0.12 12.6 0.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2621 PF11084.3 CEP15526.1 - 0.16 11.6 0.3 0.8 9.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2621) V_ATPase_I PF01496.14 CEP15526.1 - 0.24 9.2 8.5 0.28 9.0 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Matrilin_ccoil PF10393.4 CEP15526.1 - 0.7 9.3 5.1 6.7 6.1 0.1 2.5 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Gemini_C4 PF01492.12 CEP15526.1 - 0.77 9.5 5.2 1.7 8.4 3.6 1.6 1 0 0 1 1 1 0 Geminivirus C4 protein SOBP PF15279.1 CEP15526.1 - 0.82 9.9 6.6 1.1 9.5 4.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2968 PF11180.3 CEP15526.1 - 0.83 9.0 11.7 1.3 8.3 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF724 PF05266.9 CEP15526.1 - 0.99 8.9 11.0 1.7 8.2 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.3 CEP15526.1 - 1.4 8.1 15.9 3.8 6.7 11.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.3 CEP15526.1 - 1.8 8.4 17.4 5.1 6.9 12.1 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA_23 PF13476.1 CEP15526.1 - 2.5 8.3 12.5 2.2 8.5 7.7 1.6 2 0 0 2 2 2 0 AAA domain Adeno_PIX PF03955.9 CEP15526.1 - 3.1 8.3 8.1 1.1 9.7 2.9 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Rootletin PF15035.1 CEP15526.1 - 4.2 7.3 18.0 28 4.6 12.5 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.4 CEP15526.1 - 5.9 5.7 14.4 9.8 5.0 10.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 CEP15526.1 - 7 7.1 12.2 0.46 10.9 2.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 CEP15526.1 - 9 5.8 15.4 17 4.9 10.7 1.5 1 1 0 1 1 1 0 IncA protein Senescence_reg PF04520.8 CEP15527.1 - 0.022 15.2 0.9 0.022 15.2 0.6 3.3 2 1 1 3 3 3 0 Senescence regulator Nbl1_Borealin_N PF10444.4 CEP15527.1 - 0.059 12.7 3.0 0.16 11.3 2.1 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Consortin_C PF15281.1 CEP15527.1 - 5.5 6.5 7.2 0.42 10.1 0.7 2.3 3 0 0 3 3 3 0 Consortin C-terminus Cyto_heme_lyase PF01265.12 CEP15528.1 - 3e-85 285.9 8.8 8e-85 284.5 6.1 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase BsuPI PF12690.2 CEP15528.1 - 0.063 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Methyltransf_16 PF10294.4 CEP15529.1 - 4.2e-28 97.9 0.0 5.7e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 CEP15529.1 - 0.00013 22.3 0.0 0.00038 20.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP15529.1 - 0.00024 20.8 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP15529.1 - 0.00083 18.9 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP15529.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.10 CEP15529.1 - 0.045 13.1 0.0 0.21 10.9 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Smr PF01713.16 CEP15530.1 - 4.4e-12 46.0 0.0 1.3e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CEP15530.1 - 3e-07 29.7 0.1 0.00048 19.5 0.1 2.8 2 0 0 2 2 2 2 CUE domain DUF1771 PF08590.5 CEP15530.1 - 2.5e-05 24.2 0.4 7.4e-05 22.6 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) UBA PF00627.26 CEP15530.1 - 0.0013 18.4 0.1 0.14 12.0 0.0 2.8 2 0 0 2 2 2 1 UBA/TS-N domain PI3K_C2 PF00792.19 CEP15530.1 - 0.026 14.2 0.1 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 MEF2_binding PF09047.5 CEP15530.1 - 0.077 12.6 0.2 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 MEF2 binding HTH_Tnp_Tc3_2 PF01498.13 CEP15532.1 - 1.8e-09 37.5 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 CEP15532.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 CEP15533.1 - 1.9e-16 60.0 0.1 3.5e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_4 PF13837.1 CEP15534.1 - 0.046 13.8 0.7 0.2 11.8 0.0 2.4 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 CEP15535.1 - 2.2e-11 43.5 0.1 5.8e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.9 CEP15535.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein MIP PF00230.15 CEP15536.1 - 6.7e-48 163.1 16.1 8.7e-48 162.7 11.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein HCV_core PF01542.13 CEP15536.1 - 1.6 9.1 8.5 0.19 12.1 1.1 3.0 3 1 1 4 4 4 0 Hepatitis C virus core protein UQ_con PF00179.21 CEP15537.1 - 6.8e-46 155.1 0.0 1.4e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEP15537.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic E2 family B Ras PF00071.17 CEP15538.1 - 8.1e-48 161.8 0.3 9.2e-48 161.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP15538.1 - 2.5e-16 60.2 0.1 3.3e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP15538.1 - 2e-10 40.2 0.0 2.2e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP15538.1 - 3.7e-09 36.2 0.2 1.5e-08 34.3 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CEP15538.1 - 2.5e-06 26.8 0.0 1.1e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CEP15538.1 - 3.9e-05 23.5 0.0 4.9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CEP15538.1 - 0.00052 19.2 0.1 0.00078 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CEP15538.1 - 0.0081 16.0 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CEP15538.1 - 0.024 14.3 0.1 0.025 14.2 0.1 1.3 1 1 0 1 1 1 0 Archaeal ATPase ArgK PF03308.11 CEP15538.1 - 0.061 12.0 0.0 2 7.1 0.0 2.2 2 0 0 2 2 2 0 ArgK protein DDE_3 PF13358.1 CEP15539.1 - 0.048 13.4 0.1 0.075 12.7 0.1 1.3 1 1 0 1 1 1 0 DDE superfamily endonuclease Glyco_hydro_cc PF11790.3 CEP15539.1 - 0.053 12.9 0.1 0.082 12.3 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase catalytic core Ribosomal_L7Ae PF01248.21 CEP15540.1 - 1.2e-22 79.2 1.6 2.2e-22 78.3 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Arch_ATPase PF01637.13 CEP15540.1 - 0.12 11.9 0.7 0.24 11.0 0.5 1.5 1 0 0 1 1 1 0 Archaeal ATPase Ribosomal_S10 PF00338.17 CEP15542.1 - 4.6e-32 109.7 0.9 5.4e-32 109.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e SNARE_assoc PF09335.6 CEP15543.1 - 3.1e-17 62.9 6.9 3.1e-17 62.9 4.8 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein SID-1_RNA_chan PF13965.1 CEP15543.1 - 0.029 12.5 0.0 0.066 11.3 0.0 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mit_KHE1 PF10173.4 CEP15543.1 - 0.097 12.5 0.6 0.16 11.8 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF3154 PF11351.3 CEP15543.1 - 0.2 11.3 1.7 0.25 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Amino_oxidase PF01593.19 CEP15544.1 - 1.4e-60 205.6 0.0 1.2e-59 202.6 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEP15544.1 - 7.2e-09 35.5 0.1 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEP15544.1 - 4e-07 29.2 0.5 0.00016 20.7 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CEP15544.1 - 1.4e-05 25.3 2.6 0.0015 18.8 0.2 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP15544.1 - 6.3e-05 22.2 0.0 0.0018 17.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEP15544.1 - 8.6e-05 22.6 0.1 0.00075 19.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEP15544.1 - 0.0018 17.3 0.0 0.0044 16.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CEP15544.1 - 0.0085 15.9 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP15544.1 - 0.02 13.8 0.3 3.6 6.4 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 CEP15544.1 - 0.025 13.4 1.4 0.049 12.4 0.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 CEP15544.1 - 0.04 13.0 0.3 0.075 12.1 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 CEP15544.1 - 0.041 13.6 0.4 1.7 8.4 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CEP15544.1 - 0.06 12.1 1.3 0.086 11.6 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CEP15544.1 - 2.6 6.3 4.5 2.2 6.6 0.6 2.1 2 0 0 2 2 2 0 HI0933-like protein zf-MYND PF01753.13 CEP15545.1 - 1.3e-07 31.3 16.3 4.1e-07 29.7 11.3 1.9 1 0 0 1 1 1 1 MYND finger Spt20 PF12090.3 CEP15545.1 - 0.0047 16.2 0.9 0.0047 16.2 0.6 1.6 2 0 0 2 2 2 1 Spt20 family OAD_gamma PF04277.8 CEP15545.1 - 0.081 13.3 2.0 0.39 11.1 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ctr PF04145.10 CEP15545.1 - 0.1 12.6 0.2 0.1 12.6 0.1 2.2 2 0 0 2 2 2 0 Ctr copper transporter family DUF4557 PF15101.1 CEP15545.1 - 0.39 10.5 10.6 0.064 13.1 4.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) UPF0565 PF10561.4 CEP15545.1 - 2 7.2 8.8 2.7 6.7 6.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0565 Suf PF05843.9 CEP15545.1 - 5.6 6.5 12.4 0.18 11.4 2.8 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FCP1_C PF09309.5 CEP15545.1 - 7.7 5.7 14.8 0.41 9.9 4.1 2.2 2 0 0 2 2 2 0 FCP1, C-terminal WD40 PF00400.27 CEP15546.1 - 7.3e-06 25.6 0.9 0.0027 17.5 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat CNH PF00780.17 CEP15546.1 - 0.011 15.1 4.9 0.45 9.8 0.2 2.7 1 1 0 2 2 2 0 CNH domain F-box-like PF12937.2 CEP15547.1 - 2.5e-05 23.9 0.8 6.4e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 CEP15547.1 - 5.9e-05 22.7 3.2 1.5 9.1 0.0 5.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.2 CEP15547.1 - 9.7e-05 21.9 0.0 0.79 9.4 0.0 4.2 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP15547.1 - 0.00036 20.1 1.6 7.1 7.0 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 CEP15547.1 - 0.0031 17.4 2.8 5.2 7.7 0.0 4.8 5 0 0 5 5 5 1 Leucine rich repeat Y_phosphatase3 PF13350.1 CEP15548.1 - 1.8e-38 132.3 0.0 3.1e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CEP15548.1 - 8.6e-12 45.0 0.1 1.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Abhydrolase_6 PF12697.2 CEP15548.1 - 1.5e-09 38.0 0.0 9.6e-07 28.8 0.0 2.3 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP15548.1 - 7.2e-09 35.5 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CEP15548.1 - 0.0013 18.5 0.2 0.019 14.8 0.0 2.6 1 1 1 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CEP15548.1 - 0.0035 16.9 0.2 0.78 9.2 0.1 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Y_phosphatase PF00102.22 CEP15548.1 - 0.0071 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Abhydrolase_2 PF02230.11 CEP15548.1 - 0.025 13.9 0.0 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 CEP15548.1 - 0.079 12.3 0.0 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Y_phosphatase2 PF03162.8 CEP15548.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 CEP15548.1 - 0.14 11.7 0.0 0.42 10.1 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain OrfB_Zn_ribbon PF07282.6 CEP15551.1 - 2.8e-08 33.3 0.4 6.9e-08 32.0 0.3 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RuBisCO_large PF00016.15 CEP15551.1 - 0.00044 19.1 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain DUF1062 PF06353.7 CEP15551.1 - 0.2 11.8 2.7 0.4 10.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) WD40 PF00400.27 CEP15552.1 - 1.4e-58 192.7 20.4 2.1e-09 36.8 0.1 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 CEP15552.1 - 1.3e-13 50.4 0.5 3.1e-13 49.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CEP15552.1 - 1.3e-09 36.8 12.3 0.045 11.8 0.2 5.5 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 CEP15552.1 - 1.1e-06 28.1 0.6 2.1e-06 27.1 0.4 1.5 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 CEP15552.1 - 0.0011 18.7 1.4 0.037 13.8 0.0 3.7 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 CEP15552.1 - 0.0049 15.6 5.7 0.23 10.1 0.2 3.2 2 1 2 4 4 4 2 Nup133 N terminal like eIF2A PF08662.6 CEP15552.1 - 0.0078 15.9 0.0 0.12 12.1 0.0 2.7 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CEP15552.1 - 0.016 14.6 0.8 4 6.8 0.0 3.0 1 1 1 2 2 2 0 PQQ-like domain PRANC PF09372.5 CEP15552.1 - 0.14 12.1 0.3 0.49 10.4 0.2 1.9 1 1 0 1 1 1 0 PRANC domain PQQ_3 PF13570.1 CEP15552.1 - 0.22 11.8 1.7 7.4 6.9 0.0 4.3 6 0 0 6 6 6 0 PQQ-like domain ANAPC15 PF15243.1 CEP15553.1 - 0.61 10.1 10.3 1.4 9.0 6.5 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Phage_DNA_bind PF02303.12 CEP15555.1 - 0.022 14.7 0.1 0.05 13.6 0.0 1.5 2 0 0 2 2 2 0 Helix-destabilising protein CpXC PF14353.1 CEP15555.1 - 0.041 13.8 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 CpXC protein Porphobil_deam PF01379.15 CEP15558.1 - 4.2e-13 48.7 0.0 6.6e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Pox_A14 PF05767.7 CEP15558.1 - 0.061 13.2 2.4 0.24 11.3 0.0 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF1546 PF07571.8 CEP15559.1 - 4.7e-32 109.9 0.0 1.2e-31 108.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 CEP15559.1 - 4.5e-31 106.6 1.4 8.2e-31 105.7 0.1 2.1 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CEP15559.1 - 7.4e-06 25.9 0.6 0.00013 22.0 0.1 2.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 CEP15559.1 - 0.0016 18.2 0.1 0.0046 16.7 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.18 CEP15559.1 - 0.01 15.8 0.9 0.047 13.7 0.1 2.6 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CEP15559.1 - 0.043 14.0 0.4 0.49 10.7 0.1 2.7 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A TP6A_N PF04406.9 CEP15560.1 - 1.7e-18 65.9 1.3 3.5e-18 65.0 0.4 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase CAP_N PF01213.14 CEP15560.1 - 0.094 11.9 0.3 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2220 PF09983.4 CEP15560.1 - 0.099 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) HTH_28 PF13518.1 CEP15561.1 - 0.00027 20.8 0.1 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP15561.1 - 0.00052 20.1 0.3 0.0011 19.0 0.0 1.7 1 1 1 2 2 2 1 Winged helix-turn helix DDE_3 PF13358.1 CEP15561.1 - 0.026 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Cas_Cas4 PF01930.12 CEP15561.1 - 0.095 12.6 0.3 0.17 11.8 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF83 HTH_23 PF13384.1 CEP15561.1 - 0.1 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Ras PF00071.17 CEP15562.1 - 6.5e-48 162.1 0.0 8.2e-48 161.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP15562.1 - 3.8e-10 40.3 0.0 1e-09 38.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP15562.1 - 5.6e-10 38.7 0.0 7.2e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP15562.1 - 0.0065 15.9 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP15562.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Thioredoxin_6 PF13848.1 CEP15562.1 - 0.028 14.2 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain MitMem_reg PF13012.1 CEP15563.1 - 8.2e-41 138.6 1.2 1.2e-40 138.1 0.4 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CEP15563.1 - 1.1e-28 99.2 0.0 2.2e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Fungal_trans PF04082.13 CEP15564.1 - 1e-21 76.9 0.0 2.2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP15564.1 - 5.1e-10 39.0 10.5 9.5e-10 38.2 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UQ_con PF00179.21 CEP15565.1 - 4.7e-52 175.1 0.0 5.3e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEP15565.1 - 6e-06 26.0 0.0 6.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CEP15565.1 - 0.0069 16.2 0.2 0.013 15.3 0.1 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CEP15565.1 - 0.038 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Thiolase_N PF00108.18 CEP15567.1 - 5.1e-85 284.6 0.0 7e-85 284.1 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEP15567.1 - 8.3e-46 154.4 2.0 1.2e-45 153.9 0.4 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CEP15567.1 - 7.9e-07 28.7 0.4 1.9e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.7 CEP15567.1 - 0.019 14.9 0.2 7.2 6.7 0.0 3.1 3 0 0 3 3 3 0 Dodecin BTB_2 PF02214.17 CEP15568.1 - 0.036 14.2 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Ribosomal_S6e PF01092.14 CEP15569.1 - 3.3e-60 201.3 0.3 6e-60 200.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Integrase_AP2 PF14657.1 CEP15569.1 - 4.4 7.1 6.6 16 5.3 0.3 3.5 3 0 0 3 3 3 0 AP2-like DNA-binding integrase domain Y_phosphatase2 PF03162.8 CEP15570.1 - 2.7e-55 186.1 0.0 3e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CEP15570.1 - 8.6e-05 22.8 0.0 0.0011 19.2 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CEP15570.1 - 0.03 13.6 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA PF00004.24 CEP15571.1 - 0.11 12.6 0.1 0.17 12.1 0.1 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF106 PF01956.11 CEP15573.1 - 1.7e-54 183.8 0.2 1.7e-54 183.8 0.1 1.4 2 0 0 2 2 2 1 Integral membrane protein DUF106 Asp PF00026.18 CEP15574.1 - 6.1e-86 288.5 0.0 7.3e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP15574.1 - 8.6e-07 29.0 0.1 7.1e-06 26.0 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEP15574.1 - 0.087 13.3 0.1 8.1 7.0 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease Ldh_1_N PF00056.18 CEP15575.1 - 2.3e-16 59.8 0.0 3.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CEP15575.1 - 1.4e-06 28.1 0.0 2.7e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3HCDH_N PF02737.13 CEP15575.1 - 0.0018 17.9 0.2 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 CEP15575.1 - 0.0034 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family OCD_Mu_crystall PF02423.10 CEP15575.1 - 0.0081 14.9 0.1 0.013 14.2 0.0 1.4 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family DAO PF01266.19 CEP15575.1 - 0.054 12.3 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 CEP15575.1 - 0.055 12.9 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 CEP15575.1 - 0.13 12.7 0.1 0.94 9.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP15575.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lipoprotein_X PF03305.8 CEP15576.1 - 0.013 14.8 2.3 0.023 14.0 1.6 1.3 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein UPF0154 PF03672.8 CEP15576.1 - 0.024 14.2 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) L27_N PF09060.5 CEP15576.1 - 0.91 9.3 4.5 6.7 6.6 0.1 2.5 2 0 0 2 2 2 0 L27_N PDEase_I PF00233.14 CEP15577.1 - 8.5e-50 169.7 2.1 8.7e-49 166.3 1.4 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CEP15577.1 - 9.6e-07 28.8 0.9 4e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 HD domain Malic_M PF03949.10 CEP15578.1 - 2.7e-77 259.7 0.0 3.8e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CEP15578.1 - 6.5e-59 198.5 0.0 1.9e-58 197.0 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain ClpS PF02617.12 CEP15578.1 - 0.15 11.7 0.0 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS DUF2408 PF10303.4 CEP15579.1 - 1.4e-40 138.5 0.2 2e-25 89.4 0.0 4.3 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Polysacc_deac_1 PF01522.16 CEP15580.1 - 2.1e-27 95.2 0.1 3.9e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Helicase_C_3 PF13625.1 CEP15582.1 - 1.8e-29 102.0 0.0 4.5e-28 97.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP15582.1 - 7.4e-15 55.2 0.1 1.9e-14 53.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CEP15582.1 - 6.3e-12 44.9 0.0 1.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP15582.1 - 4.3e-09 36.1 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP15582.1 - 3.8e-08 33.0 0.4 1.6e-07 30.9 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase MOZ_SAS PF01853.13 CEP15584.1 - 2.6e-88 294.1 0.3 4e-88 293.6 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CEP15584.1 - 3.1e-20 71.6 0.0 7.5e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_11 PF08279.7 CEP15584.1 - 0.037 13.6 0.4 0.085 12.5 0.3 1.5 1 0 0 1 1 1 0 HTH domain WD40 PF00400.27 CEP15586.1 - 4.1e-63 207.1 12.1 3.5e-10 39.3 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP15586.1 - 0.0069 14.5 6.8 0.1 10.7 0.4 4.0 1 1 1 3 3 3 1 Nucleoporin Nup120/160 CLTH PF10607.4 CEP15586.1 - 0.01 15.5 0.6 0.025 14.2 0.1 1.9 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CEP15586.1 - 0.088 12.6 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 LisH FlxA PF14282.1 CEP15587.1 - 0.034 14.0 5.1 0.078 12.9 3.5 1.5 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.9 CEP15587.1 - 0.5 9.9 5.1 0.27 10.8 1.3 1.9 2 0 0 2 2 2 0 IncA protein F-box-like PF12937.2 CEP15589.1 - 1.7e-07 30.8 0.9 3.5e-07 29.8 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP15589.1 - 0.00055 19.5 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain Bac_globin PF01152.16 CEP15589.1 - 0.1 12.5 0.4 0.83 9.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial-like globin F-box-like PF12937.2 CEP15590.1 - 0.001 18.7 4.0 0.008 15.8 1.6 2.7 2 1 0 2 2 2 1 F-box-like DUF3053 PF11254.3 CEP15590.1 - 0.051 12.8 0.1 0.078 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) RNA_polI_A34 PF08208.6 CEP15591.1 - 1.4e-22 80.3 16.3 3.8e-22 78.9 11.3 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 CEP15591.1 - 0.0072 15.5 10.2 0.0072 15.5 7.1 1.8 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) ubiquitin PF00240.18 CEP15592.1 - 2.6e-20 71.5 0.0 4.3e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CEP15592.1 - 6.9e-11 41.6 0.3 1.2e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CEP15592.1 - 2e-06 27.4 0.2 2e-06 27.4 0.2 2.1 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 CEP15592.1 - 0.00042 20.4 0.1 0.00093 19.3 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEP15592.1 - 0.0077 16.1 0.1 0.0077 16.1 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.6 CEP15592.1 - 0.014 14.8 8.7 0.014 14.8 6.1 2.8 2 1 1 3 3 3 0 XPC-binding domain CUE PF02845.11 CEP15592.1 - 0.098 12.1 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 CUE domain DUF2362 PF10154.4 CEP15593.1 - 9.8e-65 219.1 19.5 7.1e-33 114.0 0.0 3.9 2 1 1 4 4 4 3 Uncharacterized conserved protein (DUF2362) UBA PF00627.26 CEP15593.1 - 1.7e-06 27.6 0.3 3.6e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Vps35 PF03635.12 CEP15594.1 - 0.0039 15.4 0.2 0.0042 15.3 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Cyclin PF08613.6 CEP15595.1 - 6.8e-18 65.4 0.4 1.3e-17 64.5 0.3 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP15595.1 - 1e-07 31.5 0.5 1.8e-07 30.7 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mito_fiss_reg PF05308.6 CEP15595.1 - 0.0071 15.7 6.4 0.0071 15.7 4.5 1.4 1 1 0 1 1 1 1 Mitochondrial fission regulator Biotin_lipoyl PF00364.17 CEP15596.1 - 6.2e-19 67.4 0.1 1.6e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 CEP15596.1 - 2.7e-08 33.3 0.2 6.5e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CEP15596.1 - 0.00049 19.7 0.1 0.0034 17.0 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 CEP15596.1 - 0.0027 17.0 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 HlyD family secretion protein 2-oxoacid_dh PF00198.18 CEP15596.1 - 0.0049 16.1 0.0 0.089 12.0 0.0 2.2 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) QRPTase_N PF02749.11 CEP15596.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Cytochrom_C PF00034.16 CEP15596.1 - 0.15 12.9 0.1 0.8 10.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c Polysacc_deac_1 PF01522.16 CEP15597.1 - 6.2e-36 122.7 0.0 1.3e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP15597.1 - 0.043 12.7 0.3 0.14 11.0 0.0 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 zf-met2 PF12907.2 CEP15598.1 - 2.9e-16 59.1 4.2 3.8e-16 58.7 2.9 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 CEP15598.1 - 0.61 10.8 7.1 9.4 7.0 0.2 2.2 2 0 0 2 2 2 0 4F5 protein family Erg28 PF03694.8 CEP15599.1 - 1.9e-38 130.8 2.2 1.8e-37 127.7 0.6 2.7 2 0 0 2 2 2 1 Erg28 like protein DUF3176 PF11374.3 CEP15599.1 - 7.4e-05 22.5 1.5 9.7e-05 22.2 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) TRAPPC9-Trs120 PF08626.6 CEP15600.1 - 2.7e-170 568.2 0.2 3.9e-170 567.7 0.2 1.3 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 CEP15600.1 - 0.018 14.9 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP15600.1 - 0.029 13.9 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP15600.1 - 0.042 13.7 0.1 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP15600.1 - 0.053 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 CEP15600.1 - 0.14 12.8 0.2 1.3 9.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEP15600.1 - 0.27 11.9 0.6 1.3 9.7 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Per1 PF04080.8 CEP15601.1 - 5.2e-78 262.1 15.6 5.9e-78 261.9 10.8 1.0 1 0 0 1 1 1 1 Per1-like Ferritin PF00210.19 CEP15602.1 - 8.9e-43 145.4 2.1 2e-42 144.3 1.5 1.6 1 0 0 1 1 1 1 Ferritin-like domain Aminotran_1_2 PF00155.16 CEP15602.1 - 8.6e-38 130.2 0.0 1.5e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Rubrerythrin PF02915.12 CEP15602.1 - 1.4e-05 25.3 1.4 2.2e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 Rubrerythrin Beta_elim_lyase PF01212.16 CEP15602.1 - 0.01 15.0 0.0 0.026 13.6 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase RVT_1 PF00078.22 CEP15603.1 - 5.8e-34 117.3 0.0 1.2e-33 116.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP15603.1 - 1.7e-10 41.2 1.1 3.1e-10 40.4 0.8 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP15603.1 - 1.5e-09 37.5 1.8 2.2e-09 36.9 0.2 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CEP15603.1 - 2.3e-06 27.8 0.7 8.2e-06 26.0 0.5 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 CEP15603.1 - 0.00013 21.7 15.1 0.012 15.5 1.6 2.8 2 0 0 2 2 2 2 Zinc knuckle Ribosomal_S25 PF03297.10 CEP15604.1 - 3.1e-39 133.2 2.2 3.6e-39 133.0 1.5 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 CEP15604.1 - 0.011 15.0 0.4 0.017 14.5 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 CEP15604.1 - 0.049 13.3 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 MarR family LRR_4 PF12799.2 CEP15605.1 - 1.6e-19 69.0 6.7 1.9e-05 24.1 1.0 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP15605.1 - 6.1e-12 45.1 14.3 3.3e-08 33.1 4.6 4.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CEP15605.1 - 1.1e-07 30.9 9.9 1.8 8.9 0.1 6.8 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CEP15605.1 - 0.0018 18.1 12.8 15 6.3 0.0 7.1 6 2 1 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 CEP15605.1 - 0.002 18.0 8.2 6.8 7.0 0.1 6.1 7 0 0 7 7 7 1 Leucine Rich repeat LRR_9 PF14580.1 CEP15605.1 - 0.01 15.4 0.5 2.3 7.7 0.0 2.5 1 1 0 2 2 2 0 Leucine-rich repeat DUF3138 PF11336.3 CEP15605.1 - 5.2 5.1 7.1 9.3 4.2 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Amidohydro_1 PF01979.15 CEP15606.1 - 1.4e-58 199.1 4.3 2.2e-58 198.5 3.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 CEP15606.1 - 4.9e-53 178.3 1.1 9.5e-53 177.4 0.8 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 CEP15606.1 - 3.5e-40 136.0 0.1 1.2e-39 134.2 0.0 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.15 CEP15606.1 - 6.7e-39 131.7 0.0 1.2e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.6 CEP15606.1 - 0.00014 21.2 0.1 0.00061 19.1 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 CEP15606.1 - 0.00014 21.6 2.7 0.0004 20.1 1.0 2.4 2 0 0 2 2 2 1 Amidohydrolase cobW PF02492.14 CEP15607.1 - 1.3e-33 115.9 0.0 1.6e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CEP15607.1 - 0.00037 19.3 0.4 0.17 10.6 0.0 2.3 2 1 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 CEP15607.1 - 0.0025 17.7 0.2 0.024 14.5 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 CEP15607.1 - 0.0095 16.2 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEP15607.1 - 0.013 15.2 0.0 0.038 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CEP15607.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 CEP15607.1 - 0.018 15.8 0.1 0.037 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CEP15607.1 - 0.031 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Pox_A32 PF04665.7 CEP15607.1 - 0.057 12.7 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein TIP49 PF06068.8 CEP15607.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ResIII PF04851.10 CEP15607.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CEP15607.1 - 0.12 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Lactonase PF10282.4 CEP15608.1 - 1.5e-107 359.6 0.4 1.8e-107 359.4 0.3 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller YmzC PF14157.1 CEP15608.1 - 0.0011 18.8 0.3 9.2 6.1 0.0 4.2 5 0 0 5 5 5 2 YmzC-like protein SWIB PF02201.13 CEP15609.1 - 4.5e-18 64.6 1.2 5.4e-17 61.2 0.1 2.8 3 0 0 3 3 3 1 SWIB/MDM2 domain UDPGT PF00201.13 CEP15610.1 - 8.8e-28 97.0 0.0 2e-27 95.9 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 CEP15610.1 - 2.6e-08 33.4 0.0 0.0039 16.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 CEP15610.1 - 0.0041 16.8 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ACT_7 PF13840.1 CEP15611.1 - 8e-30 102.1 0.0 2.6e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 ACT domain DUF2007 PF09413.5 CEP15611.1 - 0.0096 15.7 0.2 0.71 9.7 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2007) Ank PF00023.25 CEP15612.1 - 7.7e-13 47.5 2.6 1.3e-05 24.7 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CEP15612.1 - 2.2e-12 47.1 0.0 5.6e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP15612.1 - 5.4e-09 36.3 0.1 0.00054 20.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-met PF12874.2 CEP15612.1 - 1.8e-08 34.2 9.0 0.0034 17.5 0.1 3.9 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Ank_5 PF13857.1 CEP15612.1 - 1.8e-08 34.3 0.6 1.4e-05 25.1 0.2 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP15612.1 - 2.7e-07 30.1 0.1 0.044 14.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat zf-C2H2_2 PF12756.2 CEP15612.1 - 8.1e-06 25.8 3.5 0.0026 17.8 0.4 3.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CEP15612.1 - 5.4e-05 23.2 17.3 0.074 13.2 1.4 3.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 CEP15612.1 - 0.0072 14.8 6.0 1.2 7.5 0.5 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 CEP15612.1 - 0.015 15.5 25.6 0.23 11.8 3.7 4.3 3 0 0 3 3 3 0 C2H2-type zinc finger CENP-F_leu_zip PF10473.4 CEP15612.1 - 0.13 12.0 10.7 2.1 8.2 4.4 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mucin PF01456.12 CEP15612.1 - 0.56 9.9 17.1 1.1 8.9 11.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-C2H2_6 PF13912.1 CEP15612.1 - 1.3 8.9 13.8 0.2 11.5 1.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger SAE2 PF08573.5 CEP15612.1 - 3 8.5 8.8 88 3.9 0.1 3.9 2 1 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-C2H2 PF00096.21 CEP15612.1 - 5.7 7.4 24.9 1.1 9.7 2.7 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type PLDc_N PF13396.1 CEP15613.1 - 0.00088 18.8 3.9 0.0012 18.4 2.7 1.2 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal PilX_N PF14341.1 CEP15613.1 - 0.61 9.8 2.3 6.5 6.5 0.1 2.2 2 0 0 2 2 2 0 PilX N-terminal RRM_1 PF00076.17 CEP15614.1 - 2.3e-33 113.6 0.0 4.5e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP15614.1 - 1.6e-29 101.6 0.0 1e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP15614.1 - 2.3e-15 56.1 0.0 2e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP15614.1 - 0.004 16.8 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 CEP15614.1 - 0.0063 15.0 22.2 0.0071 14.8 15.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 CEP15614.1 - 3.8 5.0 9.5 4.7 4.8 6.6 1.3 1 0 0 1 1 1 0 Ycf1 Mito_carr PF00153.22 CEP15615.1 - 4.3e-71 234.7 0.8 9.6e-23 79.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 CEP15615.1 - 0.16 12.0 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Corticotropin-releasing factor family Pkinase PF00069.20 CEP15616.1 - 1.1e-65 221.3 0.0 2.3e-65 220.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15616.1 - 4.1e-36 124.3 0.8 7.5e-36 123.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.11 CEP15616.1 - 2.1e-17 62.6 5.0 1.1e-10 41.0 0.4 3.0 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CEP15616.1 - 2.8e-17 62.1 26.9 5.2e-10 38.8 8.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CEP15616.1 - 8e-09 35.8 2.5 2.3e-08 34.4 0.4 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain C1_2 PF03107.11 CEP15616.1 - 0.18 11.9 18.8 1.1 9.4 7.3 2.7 2 0 0 2 2 2 0 C1 domain zf-tcix PF14952.1 CEP15616.1 - 0.81 9.0 8.3 0.06 12.6 1.7 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding FYVE_2 PF02318.11 CEP15616.1 - 7.2 6.5 21.5 2.8 7.8 6.4 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger PAT1 PF09770.4 CEP15616.1 - 8.7 4.4 90.3 0.25 9.5 56.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Transposase_31 PF04754.7 CEP15617.1 - 0.00073 18.9 0.1 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative transposase, YhgA-like FHA PF00498.21 CEP15618.1 - 1.2e-06 28.5 0.1 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain GcrA PF07750.6 CEP15618.1 - 0.083 13.0 1.5 0.2 11.8 0.0 2.4 2 1 1 3 3 3 0 GcrA cell cycle regulator RNA_pol_Rpc4 PF05132.9 CEP15618.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.8 2 1 0 2 2 2 0 RNA polymerase III RPC4 LAG1-DNAbind PF09271.6 CEP15619.1 - 7.1e-25 88.1 0.3 7.1e-25 88.1 0.2 3.0 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 CEP15619.1 - 4.8e-22 78.4 1.3 8.5e-10 38.6 0.0 3.0 3 1 0 3 3 3 2 Beta-trefoil DNA-binding domain PcfJ PF14284.1 CEP15619.1 - 0.00053 19.5 3.2 0.00053 19.5 2.2 1.6 1 1 0 1 1 1 1 PcfJ-like protein Exo_endo_phos PF03372.18 CEP15620.1 - 2.5e-11 43.9 0.0 5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP15620.1 - 1.1e-05 25.0 0.8 9.8e-05 21.9 0.0 2.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF3960 PF13142.1 CEP15621.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) A2M PF00207.17 CEP15622.1 - 0.15 11.6 0.3 0.96 9.0 0.1 1.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin family Pkinase PF00069.20 CEP15623.1 - 1e-55 188.6 0.0 1.4e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15623.1 - 3.7e-23 81.9 0.0 8.7e-23 80.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15623.1 - 0.0013 17.7 0.0 0.0029 16.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like DivIC PF04977.10 CEP15623.1 - 4.7 6.7 9.0 0.26 10.8 1.7 2.3 3 0 0 3 3 3 0 Septum formation initiator RabGAP-TBC PF00566.13 CEP15624.1 - 7.4e-54 182.4 0.1 7.4e-54 182.4 0.0 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain bZIP_1 PF00170.16 CEP15624.1 - 6.7 6.7 17.7 0.89 9.5 1.5 3.4 3 0 0 3 3 3 0 bZIP transcription factor DUF713 PF05218.9 CEP15625.1 - 0.084 12.6 0.9 0.2 11.3 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF713) PAT1 PF09770.4 CEP15626.1 - 0.25 9.5 64.6 0.39 8.8 44.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mucin PF01456.12 CEP15626.1 - 0.82 9.4 34.9 1.6 8.5 11.6 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein His_biosynth PF00977.16 CEP15627.1 - 1.6e-48 164.9 0.0 1.1e-47 162.2 0.0 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 CEP15627.1 - 3.1e-29 101.7 0.0 4.6e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CEP15627.1 - 1.9e-10 40.5 0.0 4.7e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 CEP15627.1 - 4.7e-09 36.1 0.0 3.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 CEP15627.1 - 0.0032 16.9 0.2 0.03 13.7 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 BPL_N PF09825.4 CEP15627.1 - 0.026 13.3 0.0 0.061 12.1 0.0 1.5 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Dus PF01207.12 CEP15627.1 - 0.044 12.6 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Mcp5_PH PF12814.2 CEP15628.1 - 1.9e-29 102.0 0.0 1.5e-28 99.2 0.0 2.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF1363 PF07101.6 CEP15628.1 - 0.017 15.1 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) Pkinase PF00069.20 CEP15630.1 - 8.2e-58 195.5 0.0 2.2e-57 194.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15630.1 - 1.8e-40 138.6 0.7 4.8e-40 137.2 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15630.1 - 9.7e-05 21.4 2.0 0.00014 20.9 0.0 2.2 3 0 0 3 3 3 1 Kinase-like FliP PF00813.15 CEP15630.1 - 0.28 10.8 0.8 0.73 9.5 0.5 1.6 1 0 0 1 1 1 0 FliP family Ras PF00071.17 CEP15631.1 - 2.9e-58 195.8 0.3 3.9e-58 195.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP15631.1 - 2.6e-21 76.3 0.1 5.4e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP15631.1 - 2e-16 59.7 0.1 2.5e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP15631.1 - 1.3e-07 31.1 0.1 6.2e-07 29.0 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CEP15631.1 - 2.9e-07 29.8 0.2 4.3e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEP15631.1 - 6.2e-06 25.5 0.4 8.1e-06 25.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEP15631.1 - 1.5e-05 24.9 0.1 4.1e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP15631.1 - 0.00042 19.6 0.2 0.03 13.6 0.1 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.1 CEP15631.1 - 0.004 17.3 0.1 0.59 10.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CEP15631.1 - 0.032 13.9 0.5 0.38 10.4 0.3 2.0 1 1 0 1 1 1 0 Archaeal ATPase Dynamin_N PF00350.18 CEP15631.1 - 0.05 13.4 0.5 3 7.6 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 CEP15631.1 - 0.083 12.8 0.0 0.31 10.9 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain MobB PF03205.9 CEP15631.1 - 0.11 12.2 0.1 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CEP15631.1 - 0.13 12.1 0.4 0.35 10.7 0.3 1.8 2 1 0 2 2 2 0 AAA domain SurE PF01975.12 CEP15632.1 - 3.5e-48 163.5 0.0 4.6e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 CEP15632.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain DUF1576 PF07613.6 CEP15632.1 - 0.07 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) PAP1 PF08601.5 CEP15633.1 - 2.5e-09 37.2 29.9 2.5e-09 37.2 20.7 3.4 2 2 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 CEP15633.1 - 6.7e-08 32.3 12.5 1.3e-06 28.1 8.7 2.5 1 1 0 1 1 1 1 bZIP transcription factor UNC-93 PF05978.11 CEP15634.1 - 9e-12 44.7 6.9 9e-12 44.7 4.8 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CEP15634.1 - 1.6e-11 43.5 40.9 1.6e-11 43.5 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4407 PF14362.1 CEP15634.1 - 0.06 12.2 0.2 0.15 10.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LAB_N PF07578.6 CEP15634.1 - 9.7 6.1 17.0 0.44 10.5 0.2 4.3 5 0 0 5 5 5 0 Lipid A Biosynthesis N-terminal domain XLF PF09302.6 CEP15635.1 - 3.9e-06 26.7 1.3 6.4e-06 26.0 0.5 1.5 1 1 0 1 1 1 1 XLF (XRCC4-like factor) QRPTase_C PF01729.14 CEP15636.1 - 3e-56 189.5 0.1 3.7e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 CEP15636.1 - 3.2e-23 81.3 0.0 6.3e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain VEFS-Box PF09733.4 CEP15636.1 - 0.017 14.7 0.3 0.061 12.9 0.1 1.8 2 0 0 2 2 2 0 VEFS-Box of polycomb protein CCDC92 PF14916.1 CEP15637.1 - 0.57 9.8 17.4 0.4 10.2 0.1 3.8 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Rab5-bind PF09311.6 CEP15637.1 - 1 9.2 26.7 0.28 11.0 2.6 3.4 3 0 0 3 3 3 0 Rabaptin-like protein Lebercilin PF15619.1 CEP15637.1 - 5.9 6.2 29.7 2.9 7.2 10.4 3.2 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TSC22 PF01166.13 CEP15637.1 - 8.9 6.3 24.2 1.4 8.9 0.8 4.8 4 1 1 5 5 5 0 TSC-22/dip/bun family ADIP PF11559.3 CEP15637.1 - 9.5 6.1 35.9 0.68 9.8 10.5 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Lectin_C PF00059.16 CEP15638.1 - 0.0099 16.5 4.5 0.013 16.1 1.1 2.3 2 0 0 2 2 2 1 Lectin C-type domain PEPCK_ATP PF01293.15 CEP15639.1 - 8.8e-223 739.9 0.0 1e-222 739.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 CEP15639.1 - 0.12 12.4 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Chitin_synth_1 PF01644.12 CEP15640.1 - 1.5e-80 268.6 0.1 2.3e-80 268.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CEP15640.1 - 1.2e-32 111.4 0.2 2.5e-32 110.3 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEP15640.1 - 2e-23 82.6 2.6 1.1e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 CEP15640.1 - 2.5e-06 27.4 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEP15640.1 - 2.5e-06 27.3 6.6 2.5e-06 27.3 4.6 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DDE_3 PF13358.1 CEP15641.1 - 4.5e-25 88.1 0.1 1.9e-22 79.6 0.0 2.7 1 1 2 3 3 3 2 DDE superfamily endonuclease rve PF00665.21 CEP15641.1 - 1.1e-05 25.4 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 CEP15641.1 - 0.00062 18.9 0.0 0.0009 18.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 CEP15641.1 - 0.0098 14.6 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain rRNA_processing PF08524.6 CEP15641.1 - 0.084 12.6 0.2 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 rRNA processing DUF896 PF05979.7 CEP15641.1 - 0.092 12.3 0.2 0.29 10.7 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF427 PF04248.7 CEP15641.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF427) OrfB_Zn_ribbon PF07282.6 CEP15642.1 - 1.4e-11 43.8 1.3 1.4e-11 43.8 0.9 2.0 2 0 0 2 2 2 1 Putative transposase DNA-binding domain UPF0081 PF03652.10 CEP15642.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) Transaldolase PF00923.14 CEP15643.1 - 4.5e-100 334.4 0.1 5.1e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase 4HBT_3 PF13622.1 CEP15644.1 - 1.2e-42 146.4 0.2 1.5e-42 146.1 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CEP15644.1 - 1.7e-35 121.5 0.0 3.3e-27 94.7 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase Peptidase_M16_C PF05193.16 CEP15645.1 - 2e-38 131.9 0.1 5.4e-38 130.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CEP15645.1 - 1.7e-29 102.5 0.8 6.5e-29 100.6 0.3 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF2624 PF11116.3 CEP15645.1 - 0.3 11.6 2.0 3.1 8.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) UQ_con PF00179.21 CEP15646.1 - 1.4e-37 128.2 0.1 2.3e-37 127.5 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Velvet PF11754.3 CEP15647.1 - 3.3e-46 157.4 7.3 5.4e-46 156.7 2.4 2.6 1 1 1 2 2 2 1 Velvet factor BAG PF02179.11 CEP15648.1 - 1.1e-09 38.2 0.8 1.1e-09 38.2 0.6 2.9 2 1 0 2 2 2 1 BAG domain Tubulin PF00091.20 CEP15650.1 - 3.3e-65 219.9 0.0 5.2e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEP15650.1 - 2.5e-48 163.2 0.0 4e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CEP15650.1 - 0.032 14.2 0.2 0.075 13.0 0.0 1.8 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain DUF1619 PF07773.6 CEP15652.1 - 0.019 14.8 0.3 0.02 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) SR-25 PF10500.4 CEP15653.1 - 0.00013 21.5 9.5 0.00013 21.5 6.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.10 CEP15653.1 - 0.029 14.9 3.2 0.031 14.8 2.2 1.1 1 0 0 1 1 1 0 Chorion family 2 DUF3246 PF11596.3 CEP15653.1 - 0.063 12.5 7.9 0.079 12.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TLP-20 PF06088.6 CEP15653.1 - 0.065 12.9 1.2 0.074 12.7 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF755 PF05501.6 CEP15653.1 - 0.2 11.6 13.4 0.24 11.4 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ashwin PF15323.1 CEP15653.1 - 0.23 11.4 3.8 0.23 11.4 2.6 1.1 1 0 0 1 1 1 0 Developmental protein Period_C PF12114.3 CEP15653.1 - 0.65 9.5 6.2 0.64 9.5 4.3 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Syntaphilin PF15290.1 CEP15653.1 - 5.8 6.3 6.3 6.1 6.2 4.4 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp DUF3654 PF12376.3 CEP15654.1 - 0.035 13.9 1.4 0.045 13.5 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3654) DUF1796 PF08795.5 CEP15654.1 - 0.074 12.6 0.2 0.085 12.4 0.1 1.2 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Lyase_1 PF00206.15 CEP15655.1 - 1.8e-21 76.6 0.0 2.9e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CEP15655.1 - 2.2e-15 56.4 0.0 5.3e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 CEP15655.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Sugar_tr PF00083.19 CEP15656.1 - 4e-54 183.9 22.0 4.6e-54 183.7 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP15656.1 - 5.7e-25 87.7 39.0 5.6e-24 84.5 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.21 CEP15658.1 - 1.8e-07 31.1 9.2 0.00028 21.0 1.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP15658.1 - 9.2e-06 25.7 1.8 9.2e-06 25.7 1.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP15658.1 - 3.7e-05 23.7 7.7 0.0068 16.6 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP15658.1 - 1.4 8.8 6.8 0.67 9.9 0.7 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger TFIIA PF03153.8 CEP15658.1 - 1.9 8.2 6.0 2.3 8.0 4.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUSP PF06337.7 CEP15659.1 - 0.013 15.8 0.0 0.043 14.2 0.0 1.9 1 1 0 1 1 1 0 DUSP domain GTP_EFTU PF00009.22 CEP15660.1 - 2.5e-53 180.3 0.0 4.6e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain COBRA1 PF06209.8 CEP15660.1 - 1.1e-43 149.5 6.1 1.9e-43 148.7 4.2 1.3 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) EFG_C PF00679.19 CEP15660.1 - 3.1e-15 55.7 0.0 2e-14 53.2 0.0 2.4 3 0 0 3 3 3 1 Elongation factor G C-terminus EFG_II PF14492.1 CEP15660.1 - 9.9e-10 38.1 0.1 2.2e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CEP15660.1 - 5e-07 29.7 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 CEP15660.1 - 0.00072 19.1 0.1 0.0045 16.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV Nodulin_late PF07127.6 CEP15661.1 - 0.0012 18.9 0.7 0.0016 18.4 0.5 1.3 1 0 0 1 1 1 1 Late nodulin protein CarbpepA_inh PF02977.10 CEP15661.1 - 0.009 15.5 1.9 0.016 14.7 1.3 1.4 1 0 0 1 1 1 1 Carboxypeptidase A inhibitor Dickkopf_N PF04706.7 CEP15661.1 - 0.037 14.1 2.1 0.049 13.7 1.5 1.2 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region PP2C PF00481.16 CEP15662.1 - 4.9e-14 52.3 0.0 3.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 CEP15662.1 - 8.2e-14 51.7 0.0 1.5e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CEP15662.1 - 1.6e-10 40.7 0.0 2.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L19e PF01280.15 CEP15663.1 - 1.1e-59 200.4 10.8 1.1e-59 200.4 7.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e OmdA PF13376.1 CEP15663.1 - 6.6 6.4 9.0 1.5 8.5 0.5 2.6 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated LRR_4 PF12799.2 CEP15664.1 - 9.5e-08 31.4 13.2 1.6e-05 24.3 1.1 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP15664.1 - 0.00017 21.2 1.2 0.00017 21.2 0.8 2.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 CEP15664.1 - 0.00089 18.9 5.9 0.05 13.6 0.2 4.9 4 1 0 4 4 4 1 Leucine Rich Repeat zf-FCS PF06467.9 CEP15664.1 - 0.0044 16.6 2.4 0.012 15.2 1.7 1.8 1 1 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif LRR_7 PF13504.1 CEP15664.1 - 0.035 14.2 3.5 0.078 13.2 0.1 3.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 CEP15664.1 - 0.43 10.7 2.6 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 Leucine Rich repeat Lipase_GDSL PF00657.17 CEP15665.1 - 1.9e-17 63.9 1.2 2.4e-17 63.5 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP15665.1 - 1.3e-06 28.6 0.1 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MAPEG PF01124.13 CEP15667.1 - 9.3e-24 83.4 0.4 1.1e-23 83.2 0.3 1.0 1 0 0 1 1 1 1 MAPEG family Sulfate_transp PF00916.15 CEP15668.1 - 1.6e-64 217.6 11.3 1.6e-64 217.6 7.8 2.1 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP15668.1 - 2e-26 91.4 3.8 2.6e-26 91.1 1.2 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEP15668.1 - 4.9e-20 71.1 0.1 8.2e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain DUF2254 PF10011.4 CEP15668.1 - 0.0075 14.7 4.8 0.015 13.7 3.3 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) SHMT PF00464.14 CEP15669.1 - 6.1e-173 574.7 0.0 7.4e-173 574.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CEP15669.1 - 2.5e-05 23.5 0.0 5.2e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CEP15669.1 - 4.3e-05 22.6 0.0 0.00012 21.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II DUF4142 PF13628.1 CEP15669.1 - 0.088 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) WD40 PF00400.27 CEP15670.1 - 1.2e-17 63.0 16.0 2.9e-05 23.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CEP15670.1 - 0.00032 20.4 0.2 0.58 9.8 0.0 4.1 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Myb_DNA-binding PF00249.26 CEP15670.1 - 0.057 13.4 0.3 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pkinase_Tyr PF07714.12 CEP15671.1 - 3.8e-22 78.5 0.0 5.9e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CEP15671.1 - 5.4e-20 71.6 0.0 1.3e-19 70.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 CEP15671.1 - 0.0048 16.5 0.4 0.0079 15.7 0.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase PQQ_2 PF13360.1 CEP15671.1 - 0.13 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain APG5 PF04106.7 CEP15672.1 - 4.6e-56 189.4 0.2 7.5e-56 188.7 0.2 1.3 1 0 0 1 1 1 1 Autophagy protein Apg5 Metallophos PF00149.23 CEP15672.1 - 2.7e-12 46.4 4.9 5.6e-12 45.4 3.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homeobox_KN PF05920.6 CEP15673.1 - 1.1e-17 63.3 0.2 2.5e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CEP15673.1 - 1.1e-08 34.5 0.3 2.4e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain DUF720 PF05302.6 CEP15673.1 - 0.062 13.0 0.3 0.062 13.0 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF720) RhoGAP PF00620.22 CEP15674.1 - 9.8e-08 31.7 0.2 4.1e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 RhoGAP domain Peptidase_C34 PF05413.6 CEP15674.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Snapin_Pallidin PF14712.1 CEP15674.1 - 0.073 13.3 0.9 0.16 12.3 0.6 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DEAD PF00270.24 CEP15675.1 - 1.7e-33 115.5 0.1 7.8e-33 113.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP15675.1 - 1.9e-24 85.3 0.0 5.5e-24 83.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HAD_2 PF13419.1 CEP15675.1 - 7.6e-24 84.8 0.0 2.4e-23 83.2 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP15675.1 - 6.5e-08 33.2 0.0 1.7e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP15675.1 - 0.00011 21.7 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CEP15675.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_30 PF13604.1 CEP15675.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cys_Met_Meta_PP PF01053.15 CEP15677.1 - 3.2e-136 453.6 0.0 3.6e-136 453.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CEP15677.1 - 1.5e-10 40.5 0.0 2.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CEP15677.1 - 9.8e-10 37.9 0.0 1.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CEP15677.1 - 1.6e-09 37.0 0.1 2.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CEP15677.1 - 0.00029 20.0 0.0 0.0025 17.0 0.0 2.1 1 1 0 2 2 2 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CEP15677.1 - 0.00035 18.9 0.0 0.00049 18.5 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CEP15677.1 - 0.0044 15.7 0.0 0.006 15.3 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein GATA PF00320.22 CEP15679.1 - 8.6e-16 56.9 7.9 1.8e-15 55.9 5.5 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 CEP15679.1 - 8.5e-13 48.2 0.1 6.8e-12 45.3 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 CEP15679.1 - 2.9e-10 39.9 0.9 2.1e-09 37.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CEP15679.1 - 1.3e-07 31.9 0.1 7.7e-07 29.4 0.0 2.3 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.5 CEP15679.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold Ecl1 PF12855.2 CEP15679.1 - 0.11 11.7 7.4 2.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Life-span regulatory factor NAD_binding_6 PF08030.7 CEP15679.1 - 1.1 9.0 10.2 3.2 7.6 0.3 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Cyclin PF08613.6 CEP15680.1 - 8e-11 42.5 1.6 8.8e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CEP15680.1 - 1.1e-06 28.1 0.1 1.6e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Csm1 PF12539.3 CEP15681.1 - 3.6e-12 46.5 1.2 1.5e-11 44.6 0.0 2.4 2 1 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 FlaC_arch PF05377.6 CEP15681.1 - 0.0013 18.6 0.4 0.0046 16.8 0.3 1.9 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) EAP30 PF04157.11 CEP15681.1 - 0.02 14.0 3.8 0.046 12.8 2.7 1.6 1 0 0 1 1 1 0 EAP30/Vps36 family TSA PF03249.8 CEP15681.1 - 0.062 11.8 5.4 0.1 11.0 3.7 1.4 1 0 0 1 1 1 0 Type specific antigen Phage_GPO PF05929.6 CEP15681.1 - 0.66 9.1 5.9 1.1 8.4 4.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Thymidylat_synt PF00303.14 CEP15682.1 - 3.5e-120 400.0 0.0 4e-120 399.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF1237 PF06824.6 CEP15683.1 - 1.5e-153 511.4 0.1 1.7e-153 511.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) ACBP PF00887.14 CEP15684.1 - 1.7e-26 91.7 0.1 5.6e-26 90.0 0.0 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein SlyX PF04102.7 CEP15684.1 - 0.074 13.4 0.2 0.074 13.4 0.1 3.0 4 0 0 4 4 4 0 SlyX DUF641 PF04859.7 CEP15684.1 - 1.8 8.2 8.8 0.17 11.6 1.4 2.5 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) FdhE PF04216.7 CEP15684.1 - 3.6 7.2 6.0 0.24 11.0 0.1 1.9 2 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation DEAD PF00270.24 CEP15685.1 - 1.9e-46 157.6 0.2 7.5e-46 155.7 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP15685.1 - 4.3e-21 74.5 0.0 9.5e-21 73.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CEP15685.1 - 1.4e-20 72.5 0.5 2.6e-20 71.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SecA_DEAD PF07517.9 CEP15685.1 - 0.026 13.8 0.1 0.082 12.1 0.0 1.8 1 1 0 1 1 1 0 SecA DEAD-like domain DUF3027 PF11228.3 CEP15686.1 - 0.24 11.0 0.1 0.24 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) MRP-S31 PF15433.1 CEP15686.1 - 2.8 7.2 9.3 1 8.7 1.6 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 MCM_bind PF09739.4 CEP15687.1 - 1.9e-26 92.0 0.4 5.2e-26 90.6 0.3 1.7 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 CEP15687.1 - 2.3e-20 72.7 0.2 5.3e-20 71.5 0.2 1.7 1 0 0 1 1 1 1 Putative alanine racemase HSP90 PF00183.13 CEP15688.1 - 4.3e-81 272.9 3.1 1.8e-78 264.3 0.3 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CEP15688.1 - 3.1e-13 49.5 0.3 7.4e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CEP15688.1 - 4.2e-06 26.4 0.0 1.8e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K167R PF08065.7 CEP15688.1 - 0.02 14.9 0.1 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 K167R (NUC007) repeat Microvir_H PF04687.7 CEP15688.1 - 0.073 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Exo_endo_phos PF03372.18 CEP15689.1 - 1.3e-10 41.6 0.4 1.9e-10 41.1 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Milton PF12448.3 CEP15692.1 - 0.8 9.8 8.5 1.1 9.4 5.9 1.3 1 1 0 1 1 1 0 Kinesin associated protein NOB1_Zn_bind PF08772.6 CEP15693.1 - 0.0072 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like NatB_MDM20 PF09797.4 CEP15697.1 - 6.7e-82 275.1 10.1 6.7e-82 275.1 7.0 2.2 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit BTAD PF03704.12 CEP15697.1 - 0.0016 18.7 0.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 CEP15697.1 - 0.0024 17.7 0.9 13 5.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat GCR1_C PF12550.3 CEP15697.1 - 0.0074 16.1 0.1 0.035 13.9 0.0 2.3 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes TPR_19 PF14559.1 CEP15697.1 - 0.0094 16.2 8.9 13 6.2 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP15697.1 - 0.011 16.3 2.6 8.7 7.2 0.4 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP15697.1 - 0.083 12.8 7.9 22 5.0 0.1 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat PAT1 PF09770.4 CEP15699.1 - 0.00012 20.5 87.3 0.00012 20.5 60.5 3.5 3 1 1 4 4 4 1 Topoisomerase II-associated protein PAT1 IBN_N PF03810.14 CEP15700.1 - 2.9e-16 59.1 0.5 4.7e-15 55.2 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 CEP15700.1 - 1.4e-11 43.5 0.1 4.6e-10 38.6 0.0 2.7 3 0 0 3 3 3 1 Cse1 Xpo1 PF08389.7 CEP15700.1 - 0.0002 21.2 0.1 0.0002 21.2 0.1 3.6 3 1 0 3 3 3 1 Exportin 1-like protein RIX1 PF08167.7 CEP15700.1 - 0.011 15.4 3.6 0.38 10.4 0.1 3.9 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Aa_trans PF01490.13 CEP15701.1 - 1.4e-56 191.7 23.6 1.8e-56 191.4 16.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Metallophos PF00149.23 CEP15702.1 - 2.5e-44 151.0 0.1 3.1e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 CEP15703.1 - 1.7e-60 204.4 0.0 2.3e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15703.1 - 1.9e-32 112.3 0.0 2.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Proteasom_PSMB PF10508.4 CEP15704.1 - 6e-32 110.5 1.5 7.5e-32 110.2 1.0 1.1 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.1 CEP15704.1 - 0.0011 18.8 0.1 11 5.9 0.0 3.5 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.1 CEP15704.1 - 0.017 14.1 0.2 2 7.3 0.0 3.2 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Acyltransferase PF01553.16 CEP15708.1 - 9.4e-10 38.0 0.0 1.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Xan_ur_permease PF00860.15 CEP15709.1 - 4.7e-23 81.3 32.4 3.1e-21 75.3 22.1 2.8 2 1 0 2 2 2 2 Permease family DUF2834 PF11196.3 CEP15709.1 - 0.02 15.0 5.8 0.045 13.8 1.1 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2834) Cut8_C PF08559.5 CEP15710.1 - 0.01 15.6 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Cut8 six-helix bundle Exo_endo_phos PF03372.18 CEP15711.1 - 5.6e-06 26.4 0.9 9.7e-06 25.6 0.7 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP15711.1 - 0.0001 21.9 0.1 0.00036 20.1 0.1 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase QCR10 PF09796.4 CEP15712.1 - 0.054 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Ribosomal_S2 PF00318.15 CEP15713.1 - 1.9e-54 184.1 0.0 2.1e-30 105.5 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S2 AMP-binding PF00501.23 CEP15714.1 - 7.3e-45 153.0 0.0 1.1e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Slx4 PF09494.5 CEP15715.1 - 0.026 14.2 0.0 0.074 12.8 0.0 1.8 2 0 0 2 2 2 0 Slx4 endonuclease DUF1803 PF08820.5 CEP15715.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) F-box-like PF12937.2 CEP15716.1 - 8.3e-07 28.6 0.1 3.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 F-box-like ECH PF00378.15 CEP15719.1 - 8.1e-44 149.5 0.2 9.4e-44 149.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SAM_2 PF07647.12 CEP15720.1 - 9.9e-07 28.5 0.0 2.5e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEP15720.1 - 0.00025 21.1 0.4 0.00076 19.6 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF914 PF06027.7 CEP15722.1 - 3.8e-60 203.4 7.3 5.8e-60 202.8 5.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CEP15722.1 - 7.1e-05 21.8 10.9 0.00011 21.2 7.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP15722.1 - 0.00033 20.6 19.3 0.0011 19.0 1.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CEP15722.1 - 0.081 12.5 20.1 0.085 12.5 1.1 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family UCH PF00443.24 CEP15723.1 - 3.6e-56 190.2 1.9 6.9e-56 189.3 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP15723.1 - 6.6e-21 75.0 0.5 1.1e-20 74.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CEP15723.1 - 0.92 8.7 7.8 1 8.5 0.1 3.2 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ribosomal_L22e PF01776.12 CEP15724.1 - 3.3e-49 165.5 2.0 3.9e-49 165.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family HTH_Tnp_Tc3_2 PF01498.13 CEP15725.1 - 4.6e-06 26.5 0.5 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 CEP15725.1 - 0.00099 19.2 0.1 0.0038 17.3 0.0 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CEP15725.1 - 0.0036 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP15725.1 - 0.07 12.8 0.0 0.24 11.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain CENP-P PF13096.1 CEP15725.1 - 1 8.6 7.0 1.9 7.7 0.2 3.3 4 0 0 4 4 4 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P RVT_1 PF00078.22 CEP15726.1 - 2.4e-16 59.7 0.3 4.9e-16 58.7 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1180 PF06679.7 CEP15727.1 - 0.0059 16.5 0.5 0.0059 16.5 0.4 4.4 3 3 2 5 5 5 1 Protein of unknown function (DUF1180) Daxx PF03344.10 CEP15727.1 - 3.6 5.9 31.3 0.067 11.6 14.3 2.2 2 0 0 2 2 2 0 Daxx Family UPF0160 PF03690.8 CEP15728.1 - 3.3e-125 417.7 0.0 3.8e-125 417.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) zf-H2C2 PF09337.5 CEP15729.1 - 0.0041 16.5 0.1 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger PIP49_N PF14875.1 CEP15729.1 - 0.031 13.9 0.2 0.031 13.9 0.2 2.2 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 DUF3054 PF11255.3 CEP15729.1 - 0.2 11.4 0.2 3.3 7.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3054) AAA PF00004.24 CEP15730.1 - 2.5e-17 63.3 0.0 7.7e-17 61.7 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 CEP15730.1 - 1e-06 28.5 0.1 2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.1 CEP15730.1 - 0.00019 21.4 0.1 0.001 19.0 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CEP15730.1 - 0.00031 20.4 0.0 0.00071 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CEP15730.1 - 0.00036 21.3 0.1 0.0015 19.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CEP15730.1 - 0.00041 19.4 0.0 0.0012 17.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CEP15730.1 - 0.00085 19.4 0.0 0.0041 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP15730.1 - 0.0011 19.3 1.3 0.014 15.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CEP15730.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CEP15730.1 - 0.0011 18.6 0.5 0.0036 16.9 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CEP15730.1 - 0.0027 17.3 0.1 0.0086 15.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CEP15730.1 - 0.0049 17.0 0.0 0.019 15.1 0.0 2.1 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 CEP15730.1 - 0.0054 16.1 0.0 0.029 13.7 0.0 2.0 1 1 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 CEP15730.1 - 0.0067 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATP_bind_1 PF03029.12 CEP15730.1 - 0.009 15.5 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein KaiC PF06745.8 CEP15730.1 - 0.014 14.5 0.0 0.038 13.0 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 CEP15730.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 CEP15730.1 - 0.028 14.3 0.0 0.1 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEP15730.1 - 0.032 14.1 0.0 0.082 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CEP15730.1 - 0.04 13.9 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CEP15730.1 - 0.043 13.4 0.0 0.34 10.5 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.1 CEP15730.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain B56 PF01603.15 CEP15731.1 - 8.1e-153 508.8 7.7 1.1e-152 508.3 5.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) UDPGT PF00201.13 CEP15732.1 - 5e-26 91.3 0.0 8.2e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 CEP15732.1 - 1.9e-05 24.0 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 CEP15732.1 - 3.6e-05 23.4 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DDE_3 PF13358.1 CEP15733.1 - 7.1e-26 90.6 0.0 1e-13 51.2 0.0 2.6 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP15733.1 - 1.1e-05 25.4 0.1 0.00041 20.3 0.0 2.9 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 CEP15733.1 - 0.00035 20.7 0.0 0.00079 19.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix RelB PF04221.7 CEP15733.1 - 0.081 12.6 0.0 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 RelB antitoxin Methyltransf_28 PF02636.12 CEP15734.1 - 3.3e-74 249.4 0.0 3.9e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Noc2 PF03715.8 CEP15735.1 - 2.3e-98 328.7 4.7 2.3e-98 328.7 3.2 2.0 3 0 0 3 3 3 1 Noc2p family NOD PF06816.8 CEP15735.1 - 0.023 13.7 0.1 0.066 12.3 0.0 1.8 1 0 0 1 1 1 0 NOTCH protein Herpes_LMP2 PF07415.6 CEP15735.1 - 0.54 8.7 6.1 0.82 8.1 4.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DEAD PF00270.24 CEP15736.1 - 3.2e-39 134.1 0.5 7e-38 129.7 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP15736.1 - 6.2e-20 70.8 0.0 2.3e-19 69.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-HIT PF04438.11 CEP15736.1 - 0.00036 20.1 0.2 0.00057 19.4 0.2 1.3 1 0 0 1 1 1 1 HIT zinc finger T4SS-DNA_transf PF02534.9 CEP15736.1 - 0.041 12.4 0.0 0.089 11.3 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Lactamase_B_2 PF12706.2 CEP15737.1 - 3e-32 111.7 0.1 4.9e-32 111.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEP15737.1 - 2.6e-14 53.2 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEP15737.1 - 0.004 16.8 0.7 1.2 8.7 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily DUF1481 PF07356.7 CEP15737.1 - 0.036 13.5 0.6 13 5.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1481) ABC_tran PF00005.22 CEP15738.1 - 6.3e-46 156.0 0.0 5.4e-23 81.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CEP15738.1 - 1.7e-15 57.7 0.1 5.2e-05 23.3 0.1 4.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 CEP15738.1 - 6.7e-14 51.6 0.1 6.3e-05 22.3 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CEP15738.1 - 5.2e-09 36.9 0.8 0.00037 21.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CEP15738.1 - 9.6e-08 31.4 0.0 0.011 15.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CEP15738.1 - 2e-07 30.3 0.0 0.0008 18.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP15738.1 - 2e-07 31.1 0.0 0.036 14.2 0.0 4.1 5 0 0 5 5 3 2 AAA domain AAA PF00004.24 CEP15738.1 - 3.5e-07 30.4 0.0 0.08 13.1 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CEP15738.1 - 6.4e-07 29.4 0.0 0.042 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CEP15738.1 - 1.4e-06 28.8 0.0 0.087 13.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 CEP15738.1 - 2.3e-06 27.3 0.5 0.093 12.4 0.0 3.5 4 0 0 4 4 3 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CEP15738.1 - 2.7e-06 27.2 0.0 0.019 14.8 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase ArgK PF03308.11 CEP15738.1 - 3e-06 26.2 0.1 0.011 14.4 0.0 2.6 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 CEP15738.1 - 4.3e-06 26.3 0.1 0.41 10.0 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_15 PF13175.1 CEP15738.1 - 1.2e-05 24.6 0.0 1.1 8.2 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 CEP15738.1 - 1.5e-05 24.9 0.0 0.082 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CEP15738.1 - 1.6e-05 24.7 0.0 0.026 14.4 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CEP15738.1 - 2.8e-05 24.2 0.3 0.074 13.0 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.17 CEP15738.1 - 2.8e-05 24.2 0.0 0.36 11.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 CEP15738.1 - 3.5e-05 22.9 0.1 1.9 7.5 0.0 3.6 3 0 0 3 3 3 2 Zeta toxin AAA_18 PF13238.1 CEP15738.1 - 4.1e-05 23.8 0.1 0.12 12.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CEP15738.1 - 7.3e-05 22.4 0.0 0.23 11.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain DUF815 PF05673.8 CEP15738.1 - 8.8e-05 21.5 0.0 0.19 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Chromo PF00385.19 CEP15738.1 - 0.00014 21.4 0.2 0.0004 19.9 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_14 PF13173.1 CEP15738.1 - 0.0002 21.2 0.0 0.4 10.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CEP15738.1 - 0.00053 20.3 0.5 0.012 16.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.1 CEP15738.1 - 0.00055 19.5 0.0 1.5 8.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 CEP15738.1 - 0.00091 19.0 0.0 0.21 11.3 0.0 3.1 3 0 0 3 3 2 1 Dynamin family DUF87 PF01935.12 CEP15738.1 - 0.001 18.9 0.1 0.44 10.3 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 CEP15738.1 - 0.0014 18.1 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 CEP15738.1 - 0.0017 18.1 0.5 1.1 8.8 0.0 3.0 3 0 0 3 3 2 1 Archaeal ATPase PduV-EutP PF10662.4 CEP15738.1 - 0.0026 17.2 0.0 3.1 7.2 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 CEP15738.1 - 0.0049 15.4 0.8 4.6 5.5 0.0 3.6 3 1 1 4 4 4 0 AAA domain cobW PF02492.14 CEP15738.1 - 0.0081 15.6 0.5 0.89 8.9 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain HEAT PF02985.17 CEP15738.1 - 0.0095 15.9 0.3 0.31 11.2 0.0 3.5 3 0 0 3 3 2 1 HEAT repeat AAA_5 PF07728.9 CEP15738.1 - 0.012 15.3 0.1 5.1 6.8 0.0 3.7 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) ParcG PF10274.4 CEP15738.1 - 0.012 15.5 0.4 2 8.2 0.0 2.9 2 1 1 3 3 3 0 Parkin co-regulated protein NTPase_1 PF03266.10 CEP15738.1 - 0.02 14.5 0.1 3.1 7.4 0.1 2.9 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 CEP15738.1 - 0.028 13.8 0.0 8.5 5.7 0.0 3.3 4 0 0 4 4 2 0 AAA domain Rad17 PF03215.10 CEP15738.1 - 0.028 13.0 0.0 5.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 CEP15738.1 - 0.03 13.1 0.2 1.1 8.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 CEP15738.1 - 0.033 13.6 0.0 0.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PRK PF00485.13 CEP15738.1 - 0.038 13.5 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MutS_V PF00488.16 CEP15738.1 - 0.042 13.2 0.1 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 MutS domain V FeoB_N PF02421.13 CEP15738.1 - 0.09 12.0 0.0 6.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Adeno_IVa2 PF02456.10 CEP15738.1 - 0.12 10.9 0.0 4.6 5.7 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein SAM_2 PF07647.12 CEP15739.1 - 1.7e-14 53.3 0.3 1e-13 50.9 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEP15739.1 - 7.7e-11 42.0 0.8 6.3e-10 39.0 0.3 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.18 CEP15739.1 - 2e-06 28.1 0.0 3.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RP-C_C PF11800.3 CEP15739.1 - 0.79 9.3 3.3 0.36 10.4 0.2 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region Menin PF05053.8 CEP15739.1 - 0.83 7.7 4.4 1 7.4 3.0 1.2 1 0 0 1 1 1 0 Menin XendoU PF09412.5 CEP15740.1 - 0.1 11.5 0.1 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Endoribonuclease XendoU DDE_Tnp_1_assoc PF13808.1 CEP15740.1 - 0.14 11.8 0.1 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 DDE_Tnp_1-associated Acetyltransf_1 PF00583.19 CEP15742.1 - 1.8e-05 24.6 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP15742.1 - 0.00027 21.0 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP15742.1 - 0.0056 16.4 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 CEP15742.1 - 0.0056 16.6 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP15742.1 - 0.047 13.8 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP15742.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S27e PF01667.12 CEP15743.1 - 1.3e-28 98.2 3.5 1.3e-28 98.2 2.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S27 Acyltransferase PF01553.16 CEP15743.1 - 1.8e-12 46.8 0.0 4.2e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase IBR PF01485.16 CEP15743.1 - 0.0027 17.5 1.4 0.0087 15.9 0.3 2.1 2 0 0 2 2 2 1 IBR domain TF_Zn_Ribbon PF08271.7 CEP15743.1 - 0.01 15.1 2.6 0.025 13.8 1.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding FYVE PF01363.16 CEP15743.1 - 2.1 8.2 5.4 19 5.2 2.0 2.3 2 0 0 2 2 2 0 FYVE zinc finger MFS_1 PF07690.11 CEP15744.1 - 1.1e-37 129.5 34.9 5.7e-27 94.3 4.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 CEP15744.1 - 1.1e-09 36.8 3.1 1.5e-09 36.4 0.0 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 CEP15744.1 - 3.3e-07 29.0 26.9 1.2e-05 23.9 7.6 3.2 1 1 2 3 3 3 2 MFS/sugar transport protein RVT_1 PF00078.22 CEP15745.1 - 4.4e-30 104.6 0.0 1e-29 103.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP15745.1 - 3.4e-08 33.7 0.2 7.6e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP15745.1 - 5.4e-07 29.2 0.7 1.5e-06 27.7 0.5 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC_4 PF14392.1 CEP15745.1 - 0.0029 17.2 8.8 0.2 11.3 0.0 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-RVT PF13966.1 CEP15745.1 - 0.0065 16.7 0.8 0.0065 16.7 0.5 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 CEP15745.1 - 0.9 9.5 14.2 0.86 9.6 2.2 2.7 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.1 CEP15746.1 - 3.1e-30 104.8 0.0 1.2e-29 102.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP15746.1 - 9.4e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP15746.1 - 0.00019 20.9 0.0 0.0013 18.3 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP15746.1 - 0.00041 20.2 0.2 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_1 PF03184.14 CEP15746.1 - 0.0048 16.0 0.0 0.014 14.5 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease Terminase_5 PF06056.7 CEP15746.1 - 0.0082 15.6 0.3 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) rve PF00665.21 CEP15746.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_1 PF01527.15 CEP15746.1 - 0.024 14.5 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Transposase zf-C3HC4 PF00097.20 CEP15747.1 - 1.3e-05 24.7 4.1 1.3e-05 24.7 2.9 3.9 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP15747.1 - 4.2e-05 23.1 2.4 4.2e-05 23.1 1.7 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP15747.1 - 0.00033 20.4 4.3 0.00033 20.4 3.0 3.3 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 CEP15747.1 - 0.00086 18.9 4.0 0.00086 18.9 2.7 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEP15747.1 - 0.0015 18.3 3.9 0.0015 18.3 2.7 3.5 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CEP15747.1 - 0.003 17.5 4.3 0.003 17.5 3.0 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP15747.1 - 0.88 9.3 7.9 0.28 10.9 1.9 2.8 2 1 1 3 3 3 0 RING-type zinc-finger PAP_central PF04928.12 CEP15749.1 - 2.2e-108 360.8 0.0 3.2e-108 360.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CEP15749.1 - 7e-39 132.8 0.2 1.3e-38 132.0 0.2 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CEP15749.1 - 6e-08 32.9 0.0 1.6e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain TPR_11 PF13414.1 CEP15750.1 - 6e-30 102.7 9.0 8.4e-13 47.7 0.0 3.9 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 CEP15750.1 - 1.5e-24 84.5 0.0 3.4e-08 32.7 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 CEP15750.1 - 2.4e-22 79.0 5.5 1.1e-07 32.3 0.0 5.1 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 CEP15750.1 - 2.9e-21 73.5 0.1 4.7e-06 26.1 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CEP15750.1 - 2.7e-18 64.7 4.7 0.00059 20.2 0.2 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CEP15750.1 - 1.8e-16 58.8 1.5 0.0007 19.6 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 CEP15750.1 - 1.1e-12 48.1 0.4 0.00012 22.3 0.3 3.9 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 CEP15750.1 - 1.1e-12 47.6 0.0 2.9e-07 30.3 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP15750.1 - 2.3e-10 39.5 0.0 0.0056 16.3 0.0 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 CEP15750.1 - 5e-10 39.3 0.2 0.0011 18.9 0.1 4.9 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEP15750.1 - 3.2e-09 35.8 0.2 0.023 14.4 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP15750.1 - 2.1e-08 34.0 0.1 1.5 9.4 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CEP15750.1 - 4.6e-08 33.0 0.1 0.00057 19.9 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CEP15750.1 - 6e-05 22.8 1.6 0.41 10.5 0.1 3.6 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.1 CEP15750.1 - 0.0043 16.1 1.1 1.2 8.1 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF4248 PF14053.1 CEP15750.1 - 0.01 15.4 0.2 0.041 13.4 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4248) MIT PF04212.13 CEP15750.1 - 0.01 15.6 0.0 2.5 8.0 0.0 3.5 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 CEP15750.1 - 0.026 14.3 0.0 14 5.5 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF1641 PF07849.6 CEP15750.1 - 0.052 13.1 1.5 0.063 12.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Coatomer_E PF04733.9 CEP15750.1 - 0.069 12.3 0.0 0.33 10.0 0.0 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit VTC PF09359.5 CEP15751.1 - 1.9e-104 348.6 0.1 1.9e-104 348.6 0.0 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 CEP15751.1 - 1.9e-22 80.3 16.9 3.4e-08 33.6 0.0 4.1 2 2 2 4 4 4 3 SPX domain DUF202 PF02656.10 CEP15751.1 - 1.1e-13 51.1 3.8 1.1e-13 51.1 2.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cyt_c_ox_IV PF12270.3 CEP15751.1 - 0.14 11.9 0.7 0.27 11.0 0.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV zf-rbx1 PF12678.2 CEP15753.1 - 2.9e-07 30.4 13.8 6.6e-07 29.3 9.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger Mucin PF01456.12 CEP15753.1 - 3.4e-05 23.6 6.8 3.4e-05 23.6 4.7 2.6 3 0 0 3 3 3 1 Mucin-like glycoprotein zf-RING_2 PF13639.1 CEP15753.1 - 6.8e-05 22.6 24.8 0.0082 15.9 15.1 3.3 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP15753.1 - 0.00045 20.1 19.8 0.0044 17.0 7.4 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF1183 PF06682.7 CEP15753.1 - 0.0032 17.1 0.1 0.0032 17.1 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1183) zf-Apc11 PF12861.2 CEP15753.1 - 0.073 12.9 12.6 0.51 10.2 8.8 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CEP15753.1 - 0.12 12.0 20.2 0.24 11.0 11.2 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 CEP15753.1 - 0.23 10.9 13.6 0.037 13.4 5.5 2.5 3 0 0 3 3 3 0 P-11 zinc finger MSP1_C PF07462.6 CEP15753.1 - 0.36 9.1 1.9 0.57 8.5 1.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-RING_4 PF14570.1 CEP15753.1 - 1.3 8.7 13.6 0.14 11.7 5.7 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Kei1 PF08552.6 CEP15753.1 - 1.7 8.2 7.0 3.5 7.2 0.0 3.6 4 0 0 4 4 4 0 Inositolphosphorylceramide synthase subunit Kei1 Cornichon PF03311.9 CEP15754.1 - 8.3e-47 158.5 8.1 1.6e-46 157.5 5.6 1.4 1 0 0 1 1 1 1 Cornichon protein PAP_assoc PF03828.14 CEP15754.1 - 2.1e-16 59.6 0.1 5.6e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CEP15754.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA-synt_2b PF00587.20 CEP15755.1 - 1.1e-33 116.2 0.0 2e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEP15755.1 - 1.3e-10 41.1 0.0 4.6e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain DUF500 PF04366.7 CEP15756.1 - 5.6e-41 138.9 0.1 1.3e-40 137.7 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) Pkinase PF00069.20 CEP15757.1 - 1.2e-67 227.8 0.0 1.5e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15757.1 - 2.3e-36 125.1 0.0 3.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15757.1 - 1.3e-05 24.3 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP15757.1 - 0.00026 20.1 1.0 0.0004 19.5 0.7 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP15757.1 - 0.00034 20.4 0.4 0.0024 17.6 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CEP15757.1 - 0.0011 18.3 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CEP15757.1 - 0.037 12.8 0.6 0.054 12.2 0.4 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GSIII_N PF12437.3 CEP15758.1 - 2e-67 225.6 0.2 3.3e-67 225.0 0.1 1.3 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 CEP15758.1 - 1.6e-37 129.1 0.0 3.3e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DnaA_N PF11638.3 CEP15758.1 - 0.066 12.7 0.0 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 DnaA N-terminal domain 14-3-3 PF00244.15 CEP15759.1 - 3.6e-103 343.7 11.9 3.9e-102 340.3 8.2 1.9 1 1 0 1 1 1 1 14-3-3 protein DUF342 PF03961.8 CEP15759.1 - 0.0089 14.4 0.2 0.012 14.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) FliM PF02154.10 CEP15759.1 - 0.039 13.6 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Ima1_N PF09779.4 CEP15759.1 - 0.05 14.0 1.8 0.061 13.8 0.1 2.0 3 0 0 3 3 3 0 Ima1 N-terminal domain DDE_3 PF13358.1 CEP15761.1 - 0.0037 17.0 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease IucA_IucC PF04183.7 CEP15762.1 - 3.4e-20 72.3 0.0 6.4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.7 CEP15762.1 - 2e-13 50.5 0.1 3.6e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter PPR_2 PF13041.1 CEP15763.1 - 3.9e-29 100.3 2.3 1.1e-06 28.5 0.0 7.5 4 2 4 8 8 8 5 PPR repeat family PPR_3 PF13812.1 CEP15763.1 - 6.9e-28 94.5 4.1 0.00015 21.8 0.0 10.2 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 CEP15763.1 - 7.6e-20 69.4 5.7 0.0017 18.2 0.0 7.6 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.2 CEP15763.1 - 1.3e-08 34.1 0.1 1.3 8.5 0.0 5.7 5 0 0 5 5 5 3 PPR repeat TPR_12 PF13424.1 CEP15763.1 - 0.00037 20.3 7.5 2.7 7.9 0.0 5.6 4 2 1 5 5 5 1 Tetratricopeptide repeat ECSIT PF06239.6 CEP15763.1 - 0.004 16.0 0.2 4 6.2 0.0 4.2 2 2 2 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway Clathrin PF00637.15 CEP15763.1 - 0.036 13.6 2.4 14 5.2 0.1 4.5 3 2 3 6 6 6 0 Region in Clathrin and VPS DUF373 PF04123.8 CEP15763.1 - 0.081 11.9 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) TPR_7 PF13176.1 CEP15763.1 - 0.084 12.7 1.3 57 3.8 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat hSac2 PF12456.3 CEP15765.1 - 0.0069 15.7 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Inositol phosphatase Cofilin_ADF PF00241.15 CEP15766.1 - 2e-14 53.5 0.0 2.3e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3656 PF12392.3 CEP15766.1 - 0.016 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Collagenase SQS_PSY PF00494.14 CEP15770.1 - 4.7e-63 212.9 0.1 6.3e-63 212.5 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DAO PF01266.19 CEP15771.1 - 4.9e-17 61.8 0.0 5e-09 35.5 0.0 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 CEP15771.1 - 9.1e-15 54.6 0.0 5.7e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEP15771.1 - 3.4e-14 52.6 0.1 9.9e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEP15771.1 - 2.3e-07 29.9 0.2 9.9e-06 24.6 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CEP15771.1 - 3.6e-07 30.2 0.0 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP15771.1 - 6e-06 25.5 0.3 4.5e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CEP15771.1 - 9.8e-05 22.1 0.4 0.0063 16.2 0.1 3.2 2 2 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CEP15771.1 - 0.00014 21.9 0.0 0.099 12.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 CEP15771.1 - 0.00035 19.0 0.1 0.37 9.0 0.0 2.3 2 0 0 2 2 2 2 GDP dissociation inhibitor HI0933_like PF03486.9 CEP15771.1 - 0.00074 18.0 0.1 0.0086 14.5 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CEP15771.1 - 0.00079 18.5 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CEP15771.1 - 0.0014 17.5 1.9 0.0043 15.9 0.4 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CEP15771.1 - 0.0031 16.6 0.1 0.0046 16.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CEP15771.1 - 0.0064 16.8 2.1 0.036 14.4 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CEP15771.1 - 0.0095 15.6 0.4 0.019 14.6 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 CEP15771.1 - 0.011 14.3 1.0 0.33 9.5 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 CEP15771.1 - 0.014 14.2 0.9 0.11 11.3 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 CEP15771.1 - 0.015 15.5 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 CEP15771.1 - 0.045 13.1 0.5 0.12 11.8 0.3 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 CEP15771.1 - 0.061 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CEP15771.1 - 0.095 12.4 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 CEP15771.1 - 0.11 12.4 0.3 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.7 CEP15771.1 - 0.13 11.6 0.1 0.29 10.4 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 CEP15771.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 ThiF family F420_oxidored PF03807.12 CEP15771.1 - 0.19 12.1 1.3 5.9 7.3 0.4 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent LRR_6 PF13516.1 CEP15772.1 - 5.9e-16 56.6 39.5 0.034 14.2 2.7 10.9 11 0 0 11 11 11 6 Leucine Rich repeat LRR_1 PF00560.28 CEP15772.1 - 3.8e-11 41.4 24.3 1.1 9.5 0.3 10.8 9 2 1 10 10 10 5 Leucine Rich Repeat LRR_4 PF12799.2 CEP15772.1 - 0.00019 20.9 44.0 0.062 12.9 0.6 7.9 5 3 4 10 10 10 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CEP15772.1 - 0.015 15.3 32.8 9.5 6.9 0.0 10.1 11 1 0 11 11 11 0 Leucine rich repeat LRR_8 PF13855.1 CEP15772.1 - 0.16 11.7 33.9 0.16 11.7 5.0 6.4 5 3 0 5 5 5 0 Leucine rich repeat Exo_endo_phos PF03372.18 CEP15776.1 - 2.4e-12 47.3 1.1 4.1e-12 46.5 0.8 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP15776.1 - 1.2e-07 31.3 0.0 3.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 CEP15776.1 - 0.063 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SNAPc19 PF15497.1 CEP15776.1 - 0.094 12.9 0.2 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 RVT_1 PF00078.22 CEP15777.1 - 1.3e-23 83.4 0.0 2.7e-23 82.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ImpE PF07024.8 CEP15777.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 ImpE protein Lipase_bact_N PF12262.3 CEP15778.1 - 0.054 12.7 0.1 0.095 11.8 0.0 1.4 2 0 0 2 2 2 0 Bacterial virulence factor lipase N-terminal NolV PF06635.7 CEP15779.1 - 0.11 11.7 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Nodulation protein NolV DDE_3 PF13358.1 CEP15781.1 - 1e-17 64.2 0.1 2.5e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease COesterase PF00135.23 CEP15781.1 - 0.094 11.4 0.8 0.12 11.1 0.5 1.1 1 0 0 1 1 1 0 Carboxylesterase family MFS_1 PF07690.11 CEP15782.1 - 5.5e-15 54.9 6.0 6.5e-15 54.7 4.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Septin PF00735.13 CEP15783.1 - 1.3e-115 385.2 2.1 1.8e-115 384.8 1.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEP15783.1 - 3.7e-07 30.1 0.0 8.6e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP15783.1 - 7.2e-07 28.8 0.5 1.9e-05 24.1 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEP15783.1 - 1e-05 24.7 0.1 3e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CEP15783.1 - 0.00014 22.3 0.1 0.00045 20.7 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 CEP15783.1 - 0.00081 19.5 1.8 0.0036 17.4 0.0 2.6 2 2 1 3 3 3 1 AAA domain Pox_A32 PF04665.7 CEP15783.1 - 0.0028 16.9 1.4 0.0089 15.3 0.2 2.1 2 0 0 2 2 2 1 Poxvirus A32 protein AIG1 PF04548.11 CEP15783.1 - 0.0035 16.4 0.2 0.009 15.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AAA_24 PF13479.1 CEP15783.1 - 0.004 16.7 1.1 0.011 15.3 0.8 1.8 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 CEP15783.1 - 0.006 16.0 2.1 0.11 11.9 0.2 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 CEP15783.1 - 0.0071 15.7 0.6 0.019 14.3 0.4 1.7 1 1 0 1 1 1 1 Ras family AAA_33 PF13671.1 CEP15783.1 - 0.011 15.6 0.1 0.13 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 CEP15783.1 - 0.011 14.8 0.2 0.038 13.1 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region IIGP PF05049.8 CEP15783.1 - 0.012 14.4 0.0 0.025 13.3 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 CEP15783.1 - 0.021 14.3 0.2 0.021 14.3 0.2 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 CEP15783.1 - 0.021 14.5 0.2 0.051 13.2 0.2 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 CEP15783.1 - 0.026 13.9 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 CEP15783.1 - 0.032 14.5 1.9 0.07 13.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 CEP15783.1 - 0.033 14.3 0.1 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 CEP15783.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 CEP15783.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Pox_M2 PF04887.7 CEP15783.1 - 0.077 12.3 0.3 0.32 10.3 0.0 2.0 2 1 0 2 2 2 0 Poxvirus M2 protein KAP_NTPase PF07693.9 CEP15783.1 - 0.28 10.1 6.5 1.7 7.5 4.5 2.1 1 1 0 1 1 1 0 KAP family P-loop domain Dynamin_N PF00350.18 CEP15783.1 - 0.36 10.6 11.3 1.7 8.4 0.1 3.5 3 1 1 4 4 4 0 Dynamin family ATP-synt_F6 PF05511.6 CEP15783.1 - 2 8.3 6.1 1.7 8.5 0.2 2.6 2 1 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Kinesin PF00225.18 CEP15784.1 - 2.3e-97 325.7 0.0 3.4e-97 325.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DAHP_synth_1 PF00793.15 CEP15785.1 - 2.7e-98 327.9 0.0 3.2e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DSS1_SEM1 PF05160.8 CEP15786.1 - 6.7e-20 70.6 25.7 6.7e-20 70.6 17.8 1.9 1 1 1 2 2 2 1 DSS1/SEM1 family DUF2947 PF11163.3 CEP15786.1 - 0.05 13.1 10.7 0.057 12.9 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Neugrin PF06413.6 CEP15786.1 - 2.2 8.0 7.6 2.5 7.8 5.3 1.0 1 0 0 1 1 1 0 Neugrin RNA_pol_3_Rpc31 PF11705.3 CEP15786.1 - 5.7 6.7 16.7 6.2 6.6 11.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MMR_HSR1 PF01926.18 CEP15788.1 - 4.4e-20 71.7 2.9 4.9e-15 55.5 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP15788.1 - 1.5e-09 37.2 0.7 4.4e-06 26.0 0.1 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CEP15788.1 - 4.2e-07 29.5 0.2 3.5e-05 23.3 0.0 3.2 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain GN3L_Grn1 PF08701.6 CEP15788.1 - 0.0043 16.9 7.9 0.0043 16.9 5.5 2.6 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase DUF258 PF03193.11 CEP15788.1 - 0.0063 15.7 0.5 0.046 12.8 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 CEP15788.1 - 0.032 14.7 0.9 3 8.3 0.0 3.1 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CEP15788.1 - 0.039 13.7 0.7 0.039 13.7 0.5 4.2 3 2 1 4 4 4 0 Dynamin family DUF3293 PF11697.3 CEP15788.1 - 0.13 12.3 0.3 0.13 12.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) SLD3 PF08639.5 CEP15789.1 - 0.31 9.6 3.8 0.4 9.2 2.6 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Ribosomal_S30 PF04758.9 CEP15791.1 - 0.021 14.5 0.4 0.049 13.3 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein S30 FtsA PF14450.1 CEP15791.1 - 0.045 13.5 1.4 1.2 9.0 0.0 3.2 3 0 0 3 3 3 0 Cell division protein FtsA HTH_29 PF13551.1 CEP15792.1 - 8.2e-05 22.7 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.1 CEP15793.1 - 3.6e-15 55.9 0.0 4.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Kelch_3 PF13415.1 CEP15794.1 - 1.7e-18 66.2 7.5 2e-09 37.3 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP15794.1 - 6.5e-17 60.9 2.0 3.6e-05 23.7 0.0 3.9 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CEP15794.1 - 1.3e-16 60.0 2.3 2.5e-06 27.1 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP15794.1 - 2e-15 56.3 0.2 3e-05 23.8 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 CEP15794.1 - 1.7e-13 49.8 0.3 0.0013 18.2 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 CEP15794.1 - 6.6e-13 47.8 0.6 0.0019 17.8 0.0 4.1 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 CEP15794.1 - 1.3e-09 38.0 0.1 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Lin-8 PF03353.10 CEP15794.1 - 0.27 10.5 6.1 0.54 9.4 4.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rab3-GTPase_cat PF13890.1 CEP15795.1 - 0.0098 15.2 0.1 0.035 13.4 0.0 1.8 1 1 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit WD40 PF00400.27 CEP15796.1 - 5.2e-19 67.3 8.3 9.5e-06 25.3 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 CEP15796.1 - 0.0028 17.3 0.1 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Pirin PF02678.11 CEP15799.1 - 5e-33 113.1 0.0 8.3e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 CEP15799.1 - 4.5e-32 110.2 0.0 2.5e-30 104.6 0.0 2.5 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CEP15799.1 - 0.011 15.1 1.2 0.029 13.8 0.2 2.2 2 0 0 2 2 2 0 Cupin domain XAP5 PF04921.9 CEP15800.1 - 2.8e-93 311.9 12.0 2.8e-93 311.9 8.4 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator OTU PF02338.14 CEP15801.1 - 0.0057 17.2 0.0 0.02 15.4 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CEP15801.1 - 0.011 15.1 1.8 0.012 14.9 0.2 1.7 1 1 1 2 2 2 0 Peptidase C65 Otubain JmjC PF02373.17 CEP15802.1 - 3.1e-09 37.0 0.3 4.7e-08 33.2 0.2 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CEP15802.1 - 2.7e-07 30.3 7.5 4e-07 29.7 0.0 2.7 2 1 0 2 2 2 1 Cupin-like domain PHD PF00628.24 CEP15802.1 - 1.3e-06 28.0 12.0 2.4e-06 27.1 8.3 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 CEP15802.1 - 0.015 14.9 5.7 0.015 14.9 3.9 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 CEP15802.1 - 0.43 10.4 8.2 0.82 9.5 5.7 1.5 1 0 0 1 1 1 0 Ring finger domain YL1 PF05764.8 CEP15802.1 - 3.3 7.2 33.3 2.9 7.4 21.2 2.1 2 1 0 2 2 2 0 YL1 nuclear protein HTH_Tnp_Tc5 PF03221.11 CEP15803.1 - 2.9e-13 49.4 0.1 7.6e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 CEP15803.1 - 6.2e-05 22.3 0.4 0.00016 21.0 0.3 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.17 CEP15803.1 - 0.00042 20.1 0.0 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix MRP-L20 PF12824.2 CEP15803.1 - 0.011 15.6 1.3 0.011 15.6 0.9 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 DUF3322 PF11795.3 CEP15803.1 - 0.014 15.0 0.5 0.04 13.5 0.3 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) HTH_23 PF13384.1 CEP15803.1 - 0.03 13.9 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain DUF3414 PF11894.3 CEP15804.1 - 3.6e-212 707.1 38.5 4.5e-212 706.8 26.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF1681 PF07933.9 CEP15805.1 - 4.5e-59 198.5 0.0 6e-59 198.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CotH PF08757.6 CEP15806.1 - 8.3e-32 110.7 7.1 1.5e-31 109.8 4.9 1.4 1 0 0 1 1 1 1 CotH protein DUF1325 PF07039.6 CEP15807.1 - 8.9e-32 109.4 3.2 1.6e-31 108.5 2.2 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 CEP15807.1 - 0.00027 20.7 1.6 0.57 9.9 0.5 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4537) Agenet PF05641.7 CEP15807.1 - 0.0016 18.5 0.3 0.92 9.7 0.0 2.5 2 0 0 2 2 2 2 Agenet domain WD40 PF00400.27 CEP15808.1 - 2.2e-54 179.4 23.7 6.6e-09 35.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CEP15808.1 - 0.00021 21.0 0.0 0.13 11.9 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Atg14 PF10186.4 CEP15808.1 - 0.14 11.0 1.9 0.2 10.5 1.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_2 PF07716.10 CEP15809.1 - 5.4e-12 45.3 3.6 5.4e-12 45.3 2.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP15809.1 - 6.2e-09 35.6 12.2 1.4e-08 34.5 5.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 CEP15809.1 - 0.0037 17.5 5.7 0.0057 16.9 3.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor IncA PF04156.9 CEP15809.1 - 0.0039 16.8 0.4 0.0049 16.4 0.3 1.1 1 0 0 1 1 1 1 IncA protein CCDC155 PF14662.1 CEP15809.1 - 0.0097 15.5 1.3 0.014 15.0 0.9 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DivIC PF04977.10 CEP15809.1 - 0.022 14.2 2.8 0.036 13.5 1.9 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF1131 PF06572.7 CEP15809.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) ADIP PF11559.3 CEP15809.1 - 0.084 12.7 4.6 0.12 12.2 3.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 CEP15809.1 - 0.1 12.8 4.9 0.25 11.6 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF3552 PF12072.3 CEP15809.1 - 0.46 9.6 6.4 0.67 9.1 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) NOA36 PF06524.7 CEP15810.1 - 2.8 7.1 23.4 0.89 8.7 5.3 2.5 2 0 0 2 2 2 0 NOA36 protein MBOAT PF03062.14 CEP15811.1 - 1.1e-45 156.1 31.3 1.3e-45 155.9 21.7 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Orbi_NS3 PF01616.11 CEP15811.1 - 4.9 6.0 4.9 0.45 9.4 0.2 1.5 2 0 0 2 2 2 0 Orbivirus NS3 MMR_HSR1 PF01926.18 CEP15812.1 - 3.9e-14 52.5 0.0 6.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP15812.1 - 0.065 12.5 0.1 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Complex1_49kDa PF00346.14 CEP15813.1 - 1.1e-127 424.6 0.0 1.5e-127 424.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 CEP15813.1 - 0.017 13.9 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase DDE_3 PF13358.1 CEP15814.1 - 1.8e-11 44.0 0.0 2.2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HIT PF01230.18 CEP15814.1 - 0.01 16.3 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 0 HIT domain Zn_Tnp_IS1595 PF12760.2 CEP15815.1 - 0.00038 20.2 1.3 0.00063 19.4 0.9 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Elf1 PF05129.8 CEP15815.1 - 0.026 14.2 1.9 0.037 13.7 1.3 1.3 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2387 PF09526.5 CEP15815.1 - 0.04 13.8 1.2 1.7 8.6 0.8 2.1 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF3716 PF12511.3 CEP15815.1 - 0.054 13.1 2.5 0.096 12.3 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) DUF2296 PF10058.4 CEP15815.1 - 0.07 12.8 0.2 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) CpXC PF14353.1 CEP15815.1 - 0.1 12.5 1.0 0.19 11.7 0.7 1.4 1 1 0 1 1 1 0 CpXC protein Terminase_GpA PF05876.7 CEP15815.1 - 0.12 10.7 0.2 0.12 10.6 0.2 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-Mss51 PF13824.1 CEP15815.1 - 0.13 12.1 1.1 0.22 11.3 0.7 1.4 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TFIIS_C PF01096.13 CEP15815.1 - 0.14 11.8 2.4 6.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PAAR_motif PF05488.8 CEP15815.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 PAAR motif Ribosomal_L44 PF00935.14 CEP15815.1 - 0.35 10.8 3.3 5.4 7.0 0.4 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Zn-ribbon_8 PF09723.5 CEP15815.1 - 0.4 10.6 2.2 14 5.7 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.8 CEP15815.1 - 0.5 9.9 6.2 3.9 7.0 0.3 2.7 3 0 0 3 3 3 0 InsA N-terminal domain Ribosomal_L37ae PF01780.14 CEP15815.1 - 0.64 9.9 3.2 13 5.7 0.1 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family Transpos_assoc PF13963.1 CEP15815.1 - 1.4 8.9 4.6 4.2 7.4 0.3 2.1 1 1 1 2 2 2 0 Transposase-associated domain tRNA-synt_1c PF00749.16 CEP15816.1 - 1.6e-106 355.5 0.2 2.1e-106 355.1 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CEP15816.1 - 1.8e-39 134.8 0.1 4.8e-39 133.5 0.1 1.7 1 1 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CEP15816.1 - 1.9e-35 122.1 0.0 5.8e-35 120.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CEP15816.1 - 6.3e-15 55.6 5.7 1.5e-14 54.4 3.9 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 p450 PF00067.17 CEP15817.1 - 2.2e-77 260.5 0.1 2.7e-77 260.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 TroA PF01297.12 CEP15817.1 - 0.031 13.5 0.1 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family SNF5 PF04855.7 CEP15818.1 - 2.7e-74 249.7 1.3 2.7e-74 249.7 0.9 1.8 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Prp19_bind PF06991.6 CEP15819.1 - 4.8e-73 245.8 36.9 4.8e-73 245.8 25.6 2.3 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Ras PF00071.17 CEP15820.1 - 7.9e-58 194.4 0.3 9.8e-58 194.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP15820.1 - 9.1e-23 81.0 0.1 1.5e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP15820.1 - 2.9e-19 68.9 0.1 3.8e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP15820.1 - 5.3e-10 38.8 0.0 6.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEP15820.1 - 6.5e-07 29.3 0.1 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP15820.1 - 8.2e-06 25.3 0.1 1.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CEP15820.1 - 0.0018 18.2 0.2 0.0038 17.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 CEP15820.1 - 0.0063 15.2 0.4 0.046 12.4 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 CEP15820.1 - 0.0069 16.5 0.1 0.025 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CEP15820.1 - 0.028 13.6 0.1 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MCR_beta PF02241.13 CEP15820.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain NTPase_1 PF03266.10 CEP15820.1 - 0.11 12.1 0.1 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 NTPase Ank_2 PF12796.2 CEP15821.1 - 1.7e-17 63.5 3.8 1.1e-07 32.1 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP15821.1 - 5.1e-17 61.8 1.0 1.9e-10 40.9 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CEP15821.1 - 5.5e-13 48.0 0.2 5.7e-05 22.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CEP15821.1 - 5.8e-13 48.6 0.2 1.1e-05 25.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP15821.1 - 3.8e-11 42.0 2.3 0.00036 20.4 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 CEP15821.1 - 2.6e-05 23.8 0.1 0.0002 20.9 0.0 2.5 2 1 0 2 2 2 1 KilA-N domain RVP PF00077.15 CEP15822.1 - 2.4e-05 24.1 0.0 6.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEP15822.1 - 0.016 15.6 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease NARG2_C PF10505.4 CEP15822.1 - 0.043 13.0 0.2 0.072 12.2 0.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus SipA PF09052.5 CEP15822.1 - 0.09 11.1 0.4 0.13 10.6 0.3 1.1 1 0 0 1 1 1 0 Salmonella invasion protein A gag-asp_proteas PF13975.1 CEP15822.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease GAT PF03127.9 CEP15822.1 - 0.3 11.0 2.9 4.1 7.4 0.1 2.3 1 1 1 2 2 2 0 GAT domain Sec61_beta PF03911.11 CEP15826.1 - 1.1e-18 66.6 0.3 1.4e-18 66.4 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Glycogen_syn PF05693.8 CEP15827.1 - 0 1097.0 0.0 0 1096.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CEP15827.1 - 1.4e-08 34.4 0.0 1.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CEP15827.1 - 1.9e-08 34.1 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 CEP15827.1 - 0.00071 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Cullin_binding PF03556.10 CEP15828.1 - 2.8e-27 95.1 6.6 2.8e-27 95.1 4.6 1.9 1 1 1 2 2 2 1 Cullin binding NDK PF00334.14 CEP15829.1 - 1.3e-29 102.6 0.0 1.7e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PQ-loop PF04193.9 CEP15830.1 - 9.1e-34 114.8 5.0 1.1e-17 63.2 0.7 2.9 2 0 0 2 2 2 2 PQ loop repeat E1_dh PF00676.15 CEP15831.1 - 1.6e-120 401.3 0.1 2e-120 401.0 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CEP15831.1 - 0.0046 15.9 0.0 0.01 14.7 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 CEP15831.1 - 0.035 14.7 2.4 0.17 12.5 0.1 2.7 2 1 0 2 2 2 0 KRTAP type 7 family DUF155 PF02582.9 CEP15832.1 - 9.5e-61 204.7 1.4 1.7e-60 203.9 1.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FANCI_S4 PF14678.1 CEP15833.1 - 5.3e-56 189.5 8.8 1.6e-55 187.9 6.1 1.9 1 0 0 1 1 1 1 FANCI solenoid 4 FANCI_HD2 PF14680.1 CEP15833.1 - 1.6e-32 112.4 1.3 1.6e-32 112.4 0.9 2.4 2 0 0 2 2 2 1 FANCI helical domain 2 FANCI_S2 PF14676.1 CEP15833.1 - 4.3e-22 78.6 4.5 2.5e-17 63.2 0.0 3.9 4 1 1 5 5 5 2 FANCI solenoid 2 FANCI_S1 PF14675.1 CEP15833.1 - 3e-21 75.7 3.1 4e-18 65.6 1.2 3.5 1 1 2 3 3 3 2 FANCI solenoid 1 FANCI_HD1 PF14679.1 CEP15833.1 - 7.1e-17 60.9 0.1 1.3e-15 56.9 0.0 3.1 2 0 0 2 2 2 1 FANCI helical domain 1 W2 PF02020.13 CEP15834.1 - 7.6e-16 57.8 0.2 1.3e-14 53.9 0.0 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PI3Ka PF00613.15 CEP15834.1 - 0.0015 17.7 0.7 0.0034 16.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) SAPS PF04499.10 CEP15834.1 - 0.0071 15.0 0.2 0.012 14.3 0.1 1.5 1 1 1 2 2 2 1 SIT4 phosphatase-associated protein Rep_fac_C PF08542.6 CEP15835.1 - 2.3e-21 75.5 0.0 4.2e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 CEP15835.1 - 3.8e-12 46.5 0.0 7.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CEP15835.1 - 1.2e-11 44.5 0.0 8.9e-10 38.4 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 CEP15835.1 - 1.1e-08 35.0 0.0 1.7e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 CEP15835.1 - 3.9e-07 29.1 0.0 0.0011 17.7 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CEP15835.1 - 1.1e-05 25.5 0.0 0.00014 21.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CEP15835.1 - 8.9e-05 22.6 0.1 0.039 14.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CEP15835.1 - 0.00082 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CEP15835.1 - 0.00094 18.8 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 CEP15835.1 - 0.0011 18.5 0.0 0.0051 16.2 0.0 2.4 1 1 0 1 1 1 1 AAA-like domain RuvB_N PF05496.7 CEP15835.1 - 0.0014 17.7 0.0 0.0037 16.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CEP15835.1 - 0.0018 17.4 0.0 0.012 14.8 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEP15835.1 - 0.0056 16.2 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CEP15835.1 - 0.011 15.4 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 NTPase ArgK PF03308.11 CEP15835.1 - 0.032 13.0 0.1 0.11 11.3 0.0 1.8 1 1 1 2 2 2 0 ArgK protein DNA_pol3_delta PF06144.8 CEP15835.1 - 0.047 13.2 0.1 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_18 PF13238.1 CEP15835.1 - 0.058 13.6 0.1 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CEP15835.1 - 0.12 11.7 0.1 0.47 9.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.5 CEP15835.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DEAD PF00270.24 CEP15835.1 - 0.13 11.6 0.1 1.1 8.7 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase Pkinase PF00069.20 CEP15836.1 - 1.6e-58 197.9 0.0 1.9e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15836.1 - 6.4e-22 77.8 0.0 1.5e-20 73.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP15836.1 - 9.8e-07 28.7 0.2 5.5e-06 26.2 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP15836.1 - 0.0017 17.9 0.1 0.0047 16.5 0.1 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CEP15836.1 - 0.053 12.5 0.1 0.099 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHP PF02811.14 CEP15838.1 - 4.2e-11 42.9 0.0 7.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 PHP domain Ribosomal_S5 PF00333.15 CEP15839.1 - 7.1e-28 96.1 1.3 1.3e-27 95.3 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CEP15839.1 - 8.5e-23 79.4 0.1 1.4e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 CEP15839.1 - 5.9 7.4 7.8 11 6.5 5.4 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FR47 PF08445.5 CEP15840.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CEP15840.1 - 0.00088 19.3 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Chorismate_bind PF00425.13 CEP15841.1 - 1.4e-94 316.2 0.0 2.5e-94 315.3 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CEP15841.1 - 9.3e-30 103.4 0.0 8.4e-29 100.3 0.0 2.4 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Hid1 PF12722.2 CEP15842.1 - 5.7e-195 649.7 15.2 9.1e-194 645.7 10.6 2.0 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CEP15842.1 - 3.7e-91 306.2 3.2 4.7e-91 305.9 2.2 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein HisKA_2 PF07568.7 CEP15843.1 - 0.08 12.8 0.1 0.22 11.3 0.1 1.8 1 1 0 1 1 1 0 Histidine kinase DUF221 PF02714.10 CEP15844.1 - 6.5e-98 327.5 23.7 8.7e-98 327.1 16.4 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEP15844.1 - 7.7e-34 116.5 1.0 7.7e-34 116.5 0.7 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CEP15844.1 - 1.2e-12 47.5 0.1 3.1e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CEP15844.1 - 1.6e-12 47.7 0.2 3.6e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) G-alpha PF00503.15 CEP15845.1 - 6.5e-110 367.4 6.2 6e-107 357.6 4.3 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP15845.1 - 3.4e-15 55.7 0.7 2.1e-09 36.8 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP15845.1 - 0.00025 20.2 0.2 0.16 11.0 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP15845.1 - 0.0023 18.3 0.0 0.83 10.1 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 CEP15845.1 - 0.043 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UCR_UQCRX_QCR9 PF05365.7 CEP15846.1 - 3.3e-28 97.0 3.1 3.6e-28 96.9 2.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like ParA PF10609.4 CEP15847.1 - 2.3e-35 120.2 1.0 7.8e-35 118.6 0.8 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 CEP15847.1 - 1.7e-17 63.4 0.3 2.3e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CEP15847.1 - 1.1e-07 31.2 0.0 1.7e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CEP15847.1 - 1.4e-06 28.3 0.0 8.6e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 CEP15847.1 - 2.7e-06 26.7 0.1 0.002 17.3 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 CEP15847.1 - 0.00067 18.7 0.7 0.0059 15.6 0.6 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 CEP15847.1 - 0.011 15.1 2.5 0.033 13.5 1.7 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CEP15847.1 - 0.016 14.9 2.3 0.67 9.7 1.2 2.4 2 0 0 2 2 2 0 Part of AAA domain VirC1 PF07015.6 CEP15847.1 - 0.027 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein PhnA_Zn_Ribbon PF08274.7 CEP15847.1 - 0.064 13.0 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon AAA_10 PF12846.2 CEP15847.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Phage_int_SAM_4 PF13495.1 CEP15848.1 - 0.036 14.3 0.1 1.6 9.1 0.0 2.6 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain DnaB PF00772.16 CEP15850.1 - 0.098 12.5 0.1 0.58 10.0 0.0 2.0 1 1 1 2 2 2 0 DnaB-like helicase N terminal domain MULE PF10551.4 CEP15851.1 - 1.4e-09 37.9 1.3 1.1e-08 35.1 0.6 2.3 2 0 0 2 2 2 1 MULE transposase domain DUF1892 PF08987.5 CEP15851.1 - 0.0018 18.2 0.1 0.005 16.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) DUF2610 PF11020.3 CEP15851.1 - 0.014 15.2 0.0 0.047 13.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) RVT_1 PF00078.22 CEP15852.1 - 2.7e-14 53.0 0.1 1.1e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP15852.1 - 1.1e-08 34.7 0.3 3.3e-08 33.1 0.2 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP15852.1 - 5.8e-08 32.9 0.7 5.8e-08 32.9 0.5 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.1 CEP15852.1 - 1.7 8.3 10.0 0.042 13.5 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle FAR1 PF03101.10 CEP15854.1 - 0.0013 19.1 1.5 0.004 17.6 1.0 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain DDE_3 PF13358.1 CEP15855.1 - 1.9e-31 108.7 0.0 3.2e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP15855.1 - 1.6e-06 28.2 0.0 4.9e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix PAX PF00292.13 CEP15855.1 - 1.1e-05 25.1 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 CEP15855.1 - 0.00022 20.7 0.0 0.00046 19.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 CEP15855.1 - 0.0016 19.1 0.0 0.014 16.1 0.0 2.4 3 0 0 3 3 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CEP15855.1 - 0.0032 16.6 0.0 0.0072 15.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DUF4322 PF14210.1 CEP15855.1 - 0.0034 16.8 0.5 0.0083 15.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4322) rve PF00665.21 CEP15855.1 - 0.0055 16.7 0.0 0.024 14.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.1 CEP15855.1 - 0.025 14.5 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1323 PF07037.6 CEP15855.1 - 0.032 14.3 0.0 0.094 12.8 0.0 1.8 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) TrmB PF01978.14 CEP15855.1 - 0.035 13.8 0.2 0.11 12.1 0.1 1.9 2 0 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 CEP15855.1 - 0.097 12.3 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator SSXT PF05030.7 CEP15855.1 - 0.14 11.8 0.2 0.82 9.2 0.1 2.1 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Thiolase_N PF00108.18 CEP15856.1 - 4.4e-81 271.7 6.9 4.4e-81 271.7 3.3 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEP15856.1 - 3.2e-47 158.9 1.3 8.1e-47 157.6 0.1 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain bZIP_1 PF00170.16 CEP15857.1 - 2.3e-07 30.6 18.4 3.5e-06 26.8 10.6 2.7 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 CEP15857.1 - 1.1e-06 28.3 8.1 1.1e-06 28.3 5.6 3.3 2 1 1 3 3 3 2 Basic region leucine zipper CCDC-167 PF15188.1 CEP15857.1 - 1.8 8.5 11.4 4.7 7.2 7.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Methyltransf_31 PF13847.1 CEP15858.1 - 7.5e-19 67.8 0.0 8.7e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP15858.1 - 2.4e-14 53.8 0.0 3.3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP15858.1 - 1.6e-10 41.0 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP15858.1 - 2.2e-09 37.2 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP15858.1 - 3.7e-08 32.9 0.0 5.3e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CEP15858.1 - 6.9e-08 32.8 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CEP15858.1 - 3.7e-07 29.4 0.0 5.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 CEP15858.1 - 5e-07 30.0 0.0 6.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP15858.1 - 9.6e-07 29.2 0.0 1.6e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CEP15858.1 - 9.7e-06 24.8 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 CEP15858.1 - 2.4e-05 23.7 0.0 3.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CEP15858.1 - 0.0003 20.4 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CEP15858.1 - 0.00049 18.8 0.0 0.00097 17.9 0.0 1.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase AdoMet_MTase PF07757.8 CEP15858.1 - 0.0075 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TPMT PF05724.6 CEP15858.1 - 0.0091 15.4 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.6 CEP15858.1 - 0.0094 14.6 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FmrO PF07091.6 CEP15858.1 - 0.067 12.1 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 CEP15858.1 - 0.071 12.2 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CEP15858.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PIF1 PF05970.9 CEP15859.1 - 2.2e-26 92.6 0.0 3.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DUF3384 PF11864.3 CEP15860.1 - 0.0036 15.8 0.0 0.0048 15.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Suc_Fer-like PF06999.7 CEP15862.1 - 2.4e-40 138.9 0.0 4e-38 131.7 0.0 2.1 1 1 0 1 1 1 1 Sucrase/ferredoxin-like ING PF12998.2 CEP15863.1 - 9e-10 38.7 1.5 9e-10 38.7 1.1 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CEP15863.1 - 1.9e-09 37.0 7.9 3.3e-09 36.2 5.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEP15863.1 - 0.0015 17.8 2.0 0.0029 16.8 1.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CEP15863.1 - 0.047 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 CEP15863.1 - 0.24 11.4 2.9 0.49 10.4 2.0 1.5 1 0 0 1 1 1 0 RING-like domain DUF106 PF01956.11 CEP15863.1 - 0.3 10.6 2.2 1.6 8.2 0.2 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 HlyD PF00529.15 CEP15863.1 - 0.54 9.5 5.5 0.59 9.3 2.9 1.6 1 1 0 1 1 1 0 HlyD family secretion protein Cyclin_N PF00134.18 CEP15864.1 - 1.9e-11 43.6 0.9 7.2e-11 41.7 0.8 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain CybS PF05328.7 CEP15864.1 - 0.013 15.0 0.0 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 CybS TFIIB PF00382.14 CEP15864.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat F-box-like PF12937.2 CEP15867.1 - 4.5e-05 23.0 0.1 0.00013 21.5 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 CEP15868.1 - 2.6e-07 30.2 0.0 5.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like Ribosomal_L50 PF10501.4 CEP15868.1 - 0.0023 17.8 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S RVT_1 PF00078.22 CEP15869.1 - 0.00021 20.7 0.1 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.24 CEP15870.1 - 3.5e-41 140.4 0.0 7.7e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEP15870.1 - 1.3e-05 24.9 0.1 7.7e-05 22.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP15870.1 - 2.7e-05 24.2 0.1 0.0032 17.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CEP15870.1 - 0.00013 21.1 0.0 0.00035 19.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CEP15870.1 - 0.00022 21.3 0.4 0.017 15.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 CEP15870.1 - 0.00029 20.7 0.0 0.002 18.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CEP15870.1 - 0.001 18.0 0.0 0.0022 16.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 CEP15870.1 - 0.0011 18.2 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 CEP15870.1 - 0.0013 19.5 0.3 0.0055 17.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CEP15870.1 - 0.0034 16.5 0.1 0.014 14.5 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CEP15870.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP15870.1 - 0.0053 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP15870.1 - 0.0058 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CEP15870.1 - 0.0065 15.9 0.1 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CEP15870.1 - 0.019 14.0 0.1 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 CEP15870.1 - 0.019 14.5 0.1 0.74 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF1192 PF06698.6 CEP15870.1 - 0.021 14.6 1.6 0.068 12.9 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) AAA_25 PF13481.1 CEP15870.1 - 0.024 14.0 0.8 0.43 9.9 0.1 2.6 1 1 0 2 2 2 0 AAA domain KaiC PF06745.8 CEP15870.1 - 0.029 13.4 0.3 0.17 10.9 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.1 CEP15870.1 - 0.039 13.5 0.5 0.11 12.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CEP15870.1 - 0.099 12.1 0.0 0.33 10.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CEP15870.1 - 0.099 12.2 0.2 2.1 8.0 0.0 2.3 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CEP15870.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Atg14 PF10186.4 CEP15870.1 - 0.22 10.4 1.9 0.36 9.7 1.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2422 PF10337.4 CEP15871.1 - 1.9e-24 86.2 4.3 1.9e-24 86.2 3.0 4.0 3 1 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CEP15871.1 - 2.2e-15 56.7 13.2 2.2e-15 56.7 9.1 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 CEP15871.1 - 2.9e-13 49.9 0.1 6.9e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC PF04632.7 CEP15871.1 - 3e-10 39.2 23.4 1.9e-08 33.2 8.7 3.0 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.3 CEP15871.1 - 5e-06 25.4 6.4 0.00069 18.3 4.9 2.7 2 0 0 2 2 2 1 Aluminium activated malate transporter C-C_Bond_Lyase PF15617.1 CEP15871.1 - 0.021 13.6 0.2 0.082 11.7 0.0 1.9 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold ox_reductase_C PF08635.5 CEP15871.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative oxidoreductase C terminal DUF2205 PF10224.4 CEP15872.1 - 4.8e-09 35.6 0.1 6.1e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Slu7 PF11708.3 CEP15872.1 - 0.0016 18.2 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor FAR1 PF03101.10 CEP15873.1 - 0.00037 20.9 1.4 0.00037 20.9 1.0 2.4 2 0 0 2 2 2 1 FAR1 DNA-binding domain SR-25 PF10500.4 CEP15873.1 - 0.05 13.0 12.9 0.13 11.7 9.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SOBP PF15279.1 CEP15873.1 - 1.2 9.4 24.3 2.5 8.4 11.7 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein MitMem_reg PF13012.1 CEP15874.1 - 1.9e-22 79.4 0.3 3.4e-22 78.7 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CEP15874.1 - 9.6e-13 47.8 0.0 2.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PUF PF00806.14 CEP15875.1 - 2.8e-45 149.2 9.2 1.9e-06 26.9 0.0 9.1 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Nup54 PF13874.1 CEP15875.1 - 0.0078 15.8 6.7 0.019 14.6 4.6 1.7 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 IFT20 PF14931.1 CEP15875.1 - 0.01 15.7 3.2 0.01 15.7 2.2 2.9 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 HEAT PF02985.17 CEP15877.1 - 2.4e-09 36.5 0.0 0.022 14.8 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat Pkinase PF00069.20 CEP15877.1 - 6e-08 32.1 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15877.1 - 0.00016 20.8 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 CEP15877.1 - 0.00027 21.3 0.0 0.59 10.6 0.0 3.9 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 CEP15877.1 - 0.00077 19.3 0.2 1.5 8.5 0.0 3.9 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 CEP15877.1 - 0.0024 16.8 0.0 0.0059 15.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like HEAT_2 PF13646.1 CEP15877.1 - 0.0025 18.0 0.0 0.095 12.9 0.0 3.0 3 1 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 CEP15877.1 - 0.026 12.8 0.1 0.11 10.8 0.1 1.7 1 1 1 2 2 2 0 Adaptin N terminal region DUF4203 PF13886.1 CEP15878.1 - 2.9e-13 49.7 34.6 2.4e-12 46.7 24.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) Septum_form PF13845.1 CEP15878.1 - 0.0038 16.7 0.1 0.0057 16.1 0.1 1.2 1 0 0 1 1 1 1 Septum formation Sporozoite_P67 PF05642.6 CEP15878.1 - 0.011 13.6 1.6 0.015 13.1 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box-like PF12937.2 CEP15879.1 - 5.7e-08 32.3 0.1 1.5e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP15879.1 - 0.015 14.9 0.0 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 F-box domain GDPD PF03009.12 CEP15880.1 - 7e-64 215.7 0.0 1.6e-63 214.5 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 CEP15880.1 - 1.7e-45 153.2 2.4 3.2e-16 59.4 0.0 4.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 CEP15880.1 - 6.7e-24 82.4 4.3 7.8e-07 28.6 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 CEP15880.1 - 8.1e-24 83.5 0.5 1.6e-06 28.4 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) SPX PF03105.14 CEP15880.1 - 1e-22 81.2 10.3 1.5e-10 41.3 0.1 3.5 2 1 1 3 3 3 3 SPX domain Ank_5 PF13857.1 CEP15880.1 - 1.2e-20 72.9 0.4 0.00027 21.0 0.0 6.2 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP15880.1 - 4e-19 66.7 4.2 0.0076 16.3 0.0 7.7 7 0 0 7 7 7 4 Ankyrin repeat RabGAP-TBC PF00566.13 CEP15882.1 - 1.2e-24 86.9 0.0 1.2e-24 86.9 0.0 3.0 4 0 0 4 4 4 1 Rab-GTPase-TBC domain Neur_chan_memb PF02932.11 CEP15882.1 - 3.6 7.4 4.9 9.1 6.0 3.4 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Alpha_L_fucos PF01120.12 CEP15883.1 - 1.9e-82 276.9 4.5 2.5e-82 276.5 3.2 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Lipase_3 PF01764.20 CEP15884.1 - 2.8e-13 49.6 0.0 5.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) End_N_terminal PF12218.3 CEP15884.1 - 0.13 11.7 0.0 0.58 9.6 0.0 2.1 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase F_bP_aldolase PF01116.15 CEP15885.1 - 6.5e-100 333.9 0.0 7.3e-100 333.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UQ_con PF00179.21 CEP15887.1 - 5.6e-47 158.6 0.0 9.3e-47 157.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEP15887.1 - 9.6e-06 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CEP15887.1 - 0.0049 16.7 0.1 0.0086 15.9 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CEP15887.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 UEV domain NCD2 PF04905.8 CEP15887.1 - 0.59 9.9 5.9 0.86 9.3 4.1 1.2 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) DUF3446 PF11928.3 CEP15887.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) DEC-1_N PF04625.8 CEP15888.1 - 0.23 10.0 2.3 0.24 10.0 1.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SOBP PF15279.1 CEP15889.1 - 0.33 11.2 28.9 0.14 12.5 16.3 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein RAB3GAP2_N PF14655.1 CEP15889.1 - 1 8.2 6.2 0.17 10.8 1.7 1.7 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus 2-oxoacid_dh PF00198.18 CEP15890.1 - 5.3e-85 284.3 0.1 7.9e-85 283.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CEP15890.1 - 5.7e-18 64.3 0.5 1.2e-17 63.3 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CEP15890.1 - 4.5e-17 61.4 0.6 1.1e-16 60.1 0.4 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CEP15890.1 - 0.11 12.1 2.2 1.4 8.6 1.5 2.4 1 1 0 1 1 1 0 Biotin-lipoyl like DUF2611 PF11022.3 CEP15891.1 - 1.7e-19 69.6 0.3 1.8e-19 69.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DUF2080 PF09853.4 CEP15891.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) DPBB_1 PF03330.13 CEP15892.1 - 3e-10 39.9 0.1 5.1e-10 39.2 0.1 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP15892.1 - 5.6e-06 26.0 1.5 8.1e-06 25.5 1.1 1.2 1 0 0 1 1 1 1 Barwin family DUF871 PF05913.6 CEP15892.1 - 0.057 12.2 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Barwin PF00967.12 CEP15893.1 - 4e-09 36.1 3.0 5e-09 35.8 2.1 1.3 1 1 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 CEP15893.1 - 1.9e-07 30.9 0.4 3.8e-07 30.0 0.3 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Lsm_interact PF05391.6 CEP15893.1 - 0.45 10.0 3.4 13 5.4 1.1 2.3 2 0 0 2 2 2 0 Lsm interaction motif Barwin PF00967.12 CEP15894.1 - 1.9e-09 37.2 0.4 3.6e-09 36.3 0.3 1.5 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 CEP15894.1 - 2.6e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 CEP15894.1 - 0.011 15.6 0.1 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Cerato-platanin DPBB_1 PF03330.13 CEP15895.1 - 1.5e-10 40.9 1.6 1.5e-10 40.9 0.2 1.7 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP15895.1 - 3.7e-07 29.8 0.5 4.7e-07 29.4 0.4 1.3 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 CEP15895.1 - 0.066 13.2 0.2 0.099 12.6 0.2 1.4 1 0 0 1 1 1 0 Cerato-platanin DUF2715 PF10895.3 CEP15896.1 - 0.089 12.2 16.9 0.35 10.3 2.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2715) OMP_b-brl PF13505.1 CEP15896.1 - 0.28 11.1 6.6 0.41 10.5 4.5 1.4 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF3194 PF11419.3 CEP15896.1 - 8.9 6.6 23.0 5.6e+03 -2.4 15.9 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3194) Pkinase PF00069.20 CEP15897.1 - 3.3e-63 213.2 0.0 1.2e-30 106.5 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15897.1 - 2.2e-27 95.8 0.0 9.2e-17 60.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEP15897.1 - 0.087 11.7 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Glutaredoxin PF00462.19 CEP15899.1 - 2e-16 59.7 0.0 2.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Filamin PF00630.14 CEP15899.1 - 0.02 15.4 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 Filamin/ABP280 repeat GST_N_3 PF13417.1 CEP15899.1 - 0.08 13.1 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2874 PF11396.3 CEP15899.1 - 0.3 11.0 2.9 1.6 8.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2874) DUF3808 PF10300.4 CEP15900.1 - 1.3e-63 215.2 0.9 9.2e-63 212.4 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) TPR_12 PF13424.1 CEP15900.1 - 0.12 12.2 2.6 0.67 9.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.9 CEP15901.1 - 9.7e-16 58.2 1.0 3.9e-08 33.4 0.0 3.2 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP15901.1 - 4.9e-09 36.4 0.2 0.00036 20.8 0.0 3.1 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP15901.1 - 5.6e-09 35.3 0.1 7.2e-05 21.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CEP15901.1 - 6.9e-08 31.7 0.3 0.003 16.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 CEP15901.1 - 1.5e-07 30.2 0.5 0.00023 19.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 CEP15901.1 - 5.1e-07 29.5 0.3 0.012 15.3 0.0 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 CEP15901.1 - 7.9e-06 24.7 0.2 0.0022 16.7 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 CEP15901.1 - 1.1e-05 25.3 0.2 0.0018 18.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CEP15901.1 - 0.0001 22.4 0.6 0.6 10.1 0.0 3.3 1 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 CEP15901.1 - 0.00018 21.3 0.1 0.57 10.0 0.0 2.9 2 1 0 2 2 2 2 ThiF family Thi4 PF01946.12 CEP15901.1 - 0.001 18.2 0.0 0.36 9.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family TrkA_N PF02254.13 CEP15901.1 - 0.0022 17.9 0.0 3.4 7.6 0.0 2.7 2 0 0 2 2 2 2 TrkA-N domain 3HCDH_N PF02737.13 CEP15901.1 - 0.004 16.8 0.0 0.93 9.1 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CEP15901.1 - 0.0075 15.6 0.4 0.19 11.0 0.1 2.7 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 CEP15901.1 - 0.0092 15.0 0.3 1.2 8.0 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 CEP15901.1 - 0.013 14.3 0.0 1.8 7.3 0.0 2.6 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 CEP15901.1 - 0.021 13.6 0.5 0.052 12.3 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Saccharop_dh PF03435.13 CEP15901.1 - 0.026 13.4 0.4 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 CEP15901.1 - 0.039 13.7 0.1 0.93 9.3 0.0 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain GIDA PF01134.17 CEP15901.1 - 0.042 12.6 0.1 5 5.8 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.11 CEP15901.1 - 0.065 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1806 PF08830.5 CEP15901.1 - 0.12 12.1 0.1 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1806) Exo_endo_phos PF03372.18 CEP15902.1 - 4e-21 76.0 0.0 5.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.18 CEP15903.1 - 1.6e-81 273.6 0.6 2e-50 171.3 0.0 2.2 1 1 1 2 2 2 2 Kinesin motor domain DDE_3 PF13358.1 CEP15904.1 - 8.2e-23 80.7 0.0 1.2e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 CEP15904.1 - 0.0019 17.3 0.0 0.0059 15.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 CEP15904.1 - 0.0048 16.4 0.3 0.015 14.9 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.8 CEP15904.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 CEP15904.1 - 0.024 14.1 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SRF-TF PF00319.13 CEP15904.1 - 0.038 13.2 0.1 0.092 11.9 0.1 1.7 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Bot1p PF12298.3 CEP15904.1 - 0.11 12.4 0.2 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein HTH_Tnp_IS630 PF01710.11 CEP15904.1 - 0.31 10.7 2.7 0.66 9.6 1.9 1.6 1 0 0 1 1 1 0 Transposase Actin PF00022.14 CEP15905.1 - 2e-116 388.6 0.0 2.3e-116 388.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CEP15905.1 - 0.12 11.0 0.0 1.1 7.7 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein AMP-binding_C PF13193.1 CEP15906.1 - 0.019 15.8 0.0 0.033 15.1 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ATP-synt_ab PF00006.20 CEP15907.1 - 2.6e-69 232.9 0.0 3.7e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEP15907.1 - 6.1e-26 91.1 0.0 1.5e-25 89.8 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEP15907.1 - 6.8e-21 74.2 0.6 1.9e-20 72.8 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CEP15907.1 - 2.9e-05 23.8 0.2 9.8e-05 22.1 0.1 1.9 2 1 0 2 2 2 1 HAS barrel domain PX PF00787.19 CEP15908.1 - 1.2e-18 66.8 0.1 3.5e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 PX domain PCNA_C PF02747.10 CEP15909.1 - 5.4e-53 178.2 0.2 8e-53 177.7 0.1 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 CEP15909.1 - 6.2e-53 177.6 3.1 1.1e-52 176.8 0.9 2.1 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 CEP15909.1 - 8.1e-11 41.5 0.1 1e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 CEP15909.1 - 4.8e-09 35.3 0.6 1.1e-07 30.9 0.4 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 CEP15909.1 - 0.00041 19.3 0.1 0.0088 15.0 0.0 2.0 2 0 0 2 2 2 1 Hus1-like protein Arrestin_C PF02752.17 CEP15910.1 - 1e-11 45.0 0.1 2.8e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP15910.1 - 4.7e-08 32.9 0.0 3.5e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.20 CEP15911.1 - 7.4e-41 140.0 0.1 3.2e-16 59.2 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15911.1 - 4.7e-21 75.0 0.1 1.5e-07 30.7 0.0 4.1 4 1 0 4 4 4 3 Protein tyrosine kinase Chorion_2 PF03964.10 CEP15911.1 - 1.5 9.3 13.6 26 5.4 0.0 4.0 3 0 0 3 3 3 0 Chorion family 2 SH3_9 PF14604.1 CEP15912.1 - 4.2e-09 35.8 0.0 7.2e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP15912.1 - 9.1e-07 28.1 0.0 2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP15912.1 - 0.0046 16.4 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2668 PF10873.3 CEP15912.1 - 0.0092 16.1 6.0 0.0092 16.1 4.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) AJAP1_PANP_C PF15298.1 CEP15912.1 - 0.019 14.8 0.5 0.055 13.3 0.1 2.0 1 1 1 2 2 2 0 AJAP1/PANP C-terminus Pkinase PF00069.20 CEP15913.1 - 8.6e-63 211.8 0.1 3.7e-59 199.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15913.1 - 6.5e-29 100.7 0.2 8.7e-28 97.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15913.1 - 8.4e-06 24.9 0.2 0.7 8.8 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 CEP15913.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP15913.1 - 0.1 12.3 0.0 4 7.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Chordopox_A30L PF06015.7 CEP15914.1 - 1.3 8.6 4.6 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus A30L protein Methyltransf_5 PF01795.14 CEP15915.1 - 1.9e-76 257.3 0.1 2e-71 240.8 0.1 2.9 1 1 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.1 CEP15915.1 - 0.01 15.4 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 CEP15915.1 - 0.018 15.0 0.0 0.16 11.9 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 CEP15915.1 - 0.032 14.2 0.0 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CEP15915.1 - 0.058 13.9 0.1 2.9 8.5 0.0 3.0 3 1 0 3 3 3 0 Methyltransferase domain DUF4064 PF13273.1 CEP15916.1 - 0.077 13.1 0.1 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) PsbT PF01405.12 CEP15916.1 - 2.7 7.6 5.9 0.84 9.2 1.3 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre T protein CBFD_NFYB_HMF PF00808.18 CEP15917.1 - 5.8e-30 103.1 0.9 9e-30 102.5 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEP15917.1 - 5.5e-07 29.6 0.1 9.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 CEP15917.1 - 0.00083 19.1 0.4 0.0021 17.8 0.0 1.8 1 1 1 2 2 2 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 CEP15917.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 CEP15917.1 - 0.087 13.1 0.1 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A CENP-X PF09415.5 CEP15917.1 - 0.32 10.8 0.1 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Phage_Gp23 PF10669.4 CEP15917.1 - 5.7 7.0 6.6 1.4 9.0 1.6 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) TFIIA PF03153.8 CEP15919.1 - 5.4e-68 230.5 10.7 6.2e-68 230.3 7.4 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CEP15919.1 - 1.4 7.0 24.7 2 6.5 17.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ArfGap PF01412.13 CEP15920.1 - 6.4e-08 32.3 0.1 2.3e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Acetyltransf_1 PF00583.19 CEP15921.1 - 6.6e-10 38.8 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP15921.1 - 2.4e-08 33.9 0.0 3.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 CEP15921.1 - 4.6e-05 23.9 0.0 0.00041 20.8 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP15921.1 - 0.0061 16.6 0.0 0.0085 16.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP15921.1 - 0.0086 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CEP15921.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3907 PF13047.1 CEP15922.1 - 0.05 13.2 0.2 0.056 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) DUF4051 PF13260.1 CEP15922.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF59 PF01883.14 CEP15923.1 - 2.5e-09 37.0 0.1 5e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 FolB PF02152.13 CEP15923.1 - 0.12 12.5 0.3 0.26 11.4 0.1 1.8 1 1 1 2 2 2 0 Dihydroneopterin aldolase Pkinase PF00069.20 CEP15924.1 - 6.9e-62 208.9 0.0 1e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15924.1 - 2.6e-41 141.4 0.0 4.8e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CEP15924.1 - 3.7e-17 62.4 0.3 1.3e-07 31.8 0.2 2.9 2 0 0 2 2 2 2 P21-Rho-binding domain Kinase-like PF14531.1 CEP15924.1 - 5.2e-06 25.6 0.0 8.9e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP15924.1 - 0.0075 16.0 0.1 0.97 9.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEP15924.1 - 0.034 13.2 0.2 0.057 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3682 PF12446.3 CEP15924.1 - 0.36 11.1 9.4 0.87 9.8 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) zf-RING_2 PF13639.1 CEP15925.1 - 7.9e-11 41.6 6.5 1.6e-10 40.6 4.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP15925.1 - 1.1e-08 34.9 5.1 2.3e-08 34.0 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEP15925.1 - 2.5e-06 27.0 5.4 6e-06 25.8 3.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP15925.1 - 4.2e-06 26.3 4.7 7.9e-06 25.5 3.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEP15925.1 - 1.4e-05 24.6 6.9 2.7e-05 23.7 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP15925.1 - 1.6e-05 24.8 3.0 1.6e-05 24.8 2.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEP15925.1 - 0.0008 19.2 2.3 0.0019 17.9 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 CEP15925.1 - 0.012 15.4 0.5 0.021 14.6 0.4 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 CEP15925.1 - 0.2 11.4 6.6 0.037 13.7 1.8 2.0 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 CEP15925.1 - 0.42 10.6 5.4 1.3 9.0 3.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CEP15925.1 - 3.6 7.7 6.3 8.6 6.4 4.3 1.7 1 1 0 1 1 1 0 RING-variant domain BAR_2 PF10455.4 CEP15926.1 - 6.9e-51 172.8 2.7 2.1e-48 164.7 1.9 2.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CEP15926.1 - 3.8e-18 65.8 0.9 1.9e-17 63.5 0.6 1.9 1 1 0 1 1 1 1 BAR domain Asp_protease_2 PF13650.1 CEP15929.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease FAR1 PF03101.10 CEP15931.1 - 0.0015 19.0 0.4 0.0015 19.0 0.3 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain DUF4048 PF13257.1 CEP15931.1 - 0.021 14.5 1.0 0.032 13.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) NfeD PF01957.13 CEP15932.1 - 0.2 11.7 9.7 5.5 7.1 0.0 4.2 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding Cnd2 PF05786.9 CEP15933.1 - 4.2e-117 392.5 47.0 2.3e-73 247.9 24.0 3.3 1 1 1 2 2 2 2 Condensin complex subunit 2 Macoilin PF09726.4 CEP15933.1 - 1.2 7.2 7.7 4.5 5.4 2.4 2.1 2 0 0 2 2 2 0 Transmembrane protein RVT_1 PF00078.22 CEP15935.1 - 2.5e-25 89.1 0.0 5.8e-25 87.9 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP15935.1 - 0.0013 18.9 2.9 0.0033 17.6 2.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase APG6 PF04111.7 CEP15936.1 - 5.3 6.0 8.9 1.7 7.6 0.4 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 bZIP_1 PF00170.16 CEP15937.1 - 8.9e-10 38.3 14.4 1.4e-09 37.7 8.9 2.0 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP15937.1 - 2e-08 33.9 13.3 4.4e-08 32.8 5.9 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CEP15937.1 - 4.7e-05 23.5 6.3 4.7e-05 23.5 4.4 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF904 PF06005.7 CEP15937.1 - 0.023 14.9 1.2 0.082 13.2 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF904) SMC_Nse1 PF07574.8 CEP15937.1 - 0.097 12.2 1.0 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Hum_adeno_E3A PF05393.6 CEP15937.1 - 0.13 11.9 0.3 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein TCTP PF00838.12 CEP15937.1 - 0.14 12.1 0.2 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein DivIC PF04977.10 CEP15937.1 - 0.47 9.9 5.1 0.73 9.3 0.6 2.4 1 1 1 2 2 2 0 Septum formation initiator Kinetocho_Slk19 PF12709.2 CEP15937.1 - 1.1 9.3 5.8 0.54 10.3 2.1 1.9 2 0 0 2 2 2 0 Central kinetochore-associated Sulfate_transp PF00916.15 CEP15938.1 - 4.8e-73 245.5 10.3 1e-72 244.5 7.1 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP15938.1 - 2.6e-31 107.1 3.4 2.6e-31 107.1 2.3 4.5 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEP15938.1 - 3.3e-10 39.4 0.0 6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CEP15938.1 - 0.00022 21.1 0.1 0.00044 20.2 0.1 1.5 1 0 0 1 1 1 1 STAS domain Autophagy_act_C PF03987.10 CEP15939.1 - 1.2e-20 73.4 1.6 1.2e-20 73.4 1.1 1.6 1 1 1 2 2 2 1 Autophagocytosis associated protein, active-site domain Coleoptericin PF06286.6 CEP15939.1 - 0.0086 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Coleoptericin RVT_1 PF00078.22 CEP15941.1 - 2.9e-22 79.1 0.2 4.3e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1_7 PF13843.1 CEP15942.1 - 3.4e-05 23.0 0.0 3.6e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 PIF1 PF05970.9 CEP15943.1 - 5.8e-44 150.5 0.0 6.4e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Sigma70_r4_2 PF08281.7 CEP15944.1 - 0.0002 20.7 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.1 CEP15944.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP15944.1 - 0.0063 17.2 0.0 0.014 16.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain MerR_1 PF13411.1 CEP15944.1 - 0.022 14.5 0.5 0.21 11.3 0.2 2.2 1 1 1 2 2 2 0 MerR HTH family regulatory protein HTH_28 PF13518.1 CEP15944.1 - 0.032 14.2 0.2 0.088 12.8 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 CEP15944.1 - 0.065 13.1 0.1 5.2 7.0 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 CEP15944.1 - 0.072 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 CEP15945.1 - 2.7e-18 66.0 0.0 3.1e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Amidinotransf PF02274.12 CEP15945.1 - 0.075 12.1 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase DUF4494 PF14902.1 CEP15946.1 - 0.091 12.3 1.5 0.092 12.3 1.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4494) Brevenin PF03032.10 CEP15946.1 - 1.9 8.4 4.3 0.56 10.0 0.7 1.9 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family Chromo PF00385.19 CEP15947.1 - 3.6e-10 39.3 2.8 4.9e-09 35.7 0.5 2.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP15947.1 - 0.0022 17.3 1.7 0.0046 16.3 1.2 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 CEP15947.1 - 0.015 14.9 0.1 0.015 14.9 0.1 2.8 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain ABC_membrane PF00664.18 CEP15949.1 - 1.4e-105 352.6 34.8 3.5e-59 200.4 14.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP15949.1 - 1.8e-67 225.8 1.4 1.8e-34 118.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 CEP15949.1 - 4.2e-12 45.7 0.0 2.8e-05 23.4 0.0 3.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CEP15949.1 - 1.8e-10 40.0 0.1 0.00011 20.9 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 CEP15949.1 - 2.2e-09 37.5 1.4 0.00055 19.9 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 CEP15949.1 - 3e-08 34.0 0.1 0.87 9.4 0.0 4.5 3 1 0 4 4 4 2 AAA domain AAA_22 PF13401.1 CEP15949.1 - 2.7e-07 30.8 4.0 0.0017 18.4 0.3 3.8 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CEP15949.1 - 1.9e-06 27.5 0.5 0.16 11.5 0.0 4.2 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 CEP15949.1 - 2.1e-06 27.0 0.3 0.026 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CEP15949.1 - 6e-06 27.0 0.1 0.13 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CEP15949.1 - 9.6e-06 25.4 4.8 0.041 13.8 0.3 4.2 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CEP15949.1 - 2.2e-05 23.8 4.2 0.073 12.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 CEP15949.1 - 5.4e-05 23.4 3.1 2.4 8.3 1.0 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CEP15949.1 - 8.6e-05 22.4 0.1 0.29 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.17 CEP15949.1 - 0.00023 20.6 0.2 0.093 12.1 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 CEP15949.1 - 0.00048 19.8 0.6 1.5 8.4 0.1 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 CEP15949.1 - 0.0026 16.5 0.1 1 7.9 0.1 2.5 2 1 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.7 CEP15949.1 - 0.0033 16.5 0.6 1.5 7.8 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin AAA_5 PF07728.9 CEP15949.1 - 0.0072 16.0 0.3 2.6 7.7 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CEP15949.1 - 0.0077 16.5 0.1 6 7.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 CEP15949.1 - 0.012 15.0 2.4 4 6.7 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.18 CEP15949.1 - 0.022 14.6 0.1 7.1 6.6 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.8 CEP15949.1 - 0.025 13.4 0.1 0.65 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 CEP15949.1 - 0.026 13.3 1.3 1.7 7.4 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 CEP15949.1 - 0.03 14.2 0.2 6.2 6.7 0.0 3.6 4 1 0 4 4 3 0 AAA domain AAA_25 PF13481.1 CEP15949.1 - 0.031 13.6 0.4 16 4.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 CEP15949.1 - 0.036 13.7 0.4 0.96 9.0 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.1 CEP15949.1 - 0.042 13.8 0.2 1.2 9.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain ChiC PF06483.6 CEP15949.1 - 0.043 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Chitinase C Rad17 PF03215.10 CEP15949.1 - 0.046 12.4 0.1 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 CEP15949.1 - 0.052 13.7 0.4 4.2 7.6 0.0 3.3 4 0 0 4 4 2 0 RNA helicase GMC_oxred_N PF00732.14 CEP15949.1 - 0.12 11.4 0.3 3.5 6.6 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase AAA_23 PF13476.1 CEP15949.1 - 2.5 8.3 8.5 10 6.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain Lyase_1 PF00206.15 CEP15950.1 - 3.2e-121 404.3 0.0 4.2e-121 403.9 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CEP15950.1 - 4.2e-27 93.9 0.0 8.7e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus B3_4 PF03483.12 CEP15950.1 - 0.042 13.3 0.1 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 B3/4 domain Zip PF02535.17 CEP15951.1 - 1.3e-50 172.2 10.5 1.5e-50 172.0 7.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 CEP15951.1 - 1.3 8.3 12.7 0.014 14.7 2.0 2.6 2 2 1 3 3 3 0 HupE / UreJ protein DUF4448 PF14610.1 CEP15952.1 - 7.6e-08 32.0 0.2 1.3e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Myc_target_1 PF15179.1 CEP15952.1 - 0.022 14.3 2.1 0.022 14.3 0.4 1.7 1 1 1 2 2 2 0 Myc target protein 1 SET PF00856.23 CEP15953.1 - 4.1e-05 23.9 0.0 7.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 CEP15953.1 - 0.0042 16.9 14.4 0.0097 15.7 10.0 1.6 1 0 0 1 1 1 1 MYND finger DUF2164 PF09932.4 CEP15953.1 - 0.044 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Aconitase PF00330.15 CEP15954.1 - 1.8e-153 511.3 0.0 1.1e-152 508.8 0.0 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEP15954.1 - 6.1e-40 136.3 0.0 1.3e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.15 CEP15955.1 - 1.4e-192 640.3 0.0 1.7e-192 640.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEP15955.1 - 2.1e-46 157.2 0.0 5.7e-46 155.8 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Ribosomal_L3 PF00297.17 CEP15956.1 - 1.9e-120 401.2 7.7 2.2e-120 400.9 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NIF PF03031.13 CEP15957.1 - 3.1e-49 166.7 0.7 3.1e-49 166.7 0.5 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Ubiq_cyt_C_chap PF03981.7 CEP15957.1 - 4.5e-34 117.3 0.1 7.6e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF3439 PF11921.3 CEP15957.1 - 4.1 7.1 25.2 0.25 11.1 9.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CEP15957.1 - 5 4.9 29.5 0.13 10.1 12.2 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.6 CEP15957.1 - 8.6 6.0 17.8 2.7 7.6 6.4 2.3 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus NT-C2 PF10358.4 CEP15958.1 - 3.3e-11 42.8 0.4 8e-11 41.6 0.1 1.8 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L37e PF01907.14 CEP15959.1 - 1.2e-26 92.2 12.9 2.3e-26 91.3 8.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 CEP15959.1 - 0.00067 19.4 2.8 0.0011 18.7 2.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 CEP15959.1 - 0.026 14.2 1.0 0.038 13.6 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_S14 PF00253.16 CEP15959.1 - 0.039 13.3 7.3 0.11 11.8 0.1 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e DUF2616 PF11077.3 CEP15959.1 - 0.067 12.6 0.3 0.089 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) SelR PF01641.13 CEP15959.1 - 0.091 12.4 0.8 0.16 11.6 0.6 1.5 1 1 0 1 1 1 0 SelR domain zf-RING_5 PF14634.1 CEP15959.1 - 0.17 11.6 5.2 0.26 11.0 3.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ISL3 PF14690.1 CEP15959.1 - 0.23 11.5 4.8 1.3 9.0 0.5 2.6 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DNA_RNApol_7kD PF03604.8 CEP15959.1 - 0.46 9.9 4.0 2.1 7.9 0.4 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit GFA PF04828.9 CEP15959.1 - 0.61 10.0 5.4 5.4 7.0 3.2 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_2 PF13923.1 CEP15959.1 - 0.94 9.5 6.1 1.5 8.8 4.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 CEP15959.1 - 0.95 8.7 3.9 4.7 6.5 2.8 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CEP15959.1 - 1.1 8.8 5.2 23 4.6 3.9 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 CEP15959.1 - 2.9 7.6 6.5 4.7 6.9 4.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HYPF PF07503.7 CEP15959.1 - 6.6 6.2 7.8 7 6.1 3.9 2.1 2 1 1 3 3 3 0 HypF finger HEAT_2 PF13646.1 CEP15960.1 - 0.0028 17.8 0.0 2.8 8.3 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 CEP15960.1 - 0.0049 16.7 0.1 0.38 10.5 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CEP15960.1 - 0.022 14.7 0.1 22 5.4 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Profilin PF00235.14 CEP15962.1 - 1.9e-37 128.0 0.1 2.4e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 Profilin Endonuclease_7 PF02945.10 CEP15962.1 - 0.043 13.5 0.1 2.9 7.6 0.0 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII DEAD PF00270.24 CEP15963.1 - 7.2e-45 152.5 0.0 3.4e-44 150.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP15963.1 - 2.2e-21 75.4 0.2 4.8e-21 74.4 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CEP15963.1 - 2.8e-20 71.8 4.7 2.8e-20 71.8 3.3 3.0 3 0 0 3 3 3 1 DBP10CT (NUC160) domain RabGAP-TBC PF00566.13 CEP15964.1 - 1.4e-57 194.5 0.2 1.4e-57 194.5 0.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TMF_DNA_bd PF12329.3 CEP15964.1 - 0.00033 20.3 16.0 0.00033 20.3 11.1 4.2 2 1 2 4 4 4 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 CEP15964.1 - 0.004 16.3 4.6 0.01 15.0 3.2 1.7 1 0 0 1 1 1 1 Reovirus sigma C capsid protein GAS PF13851.1 CEP15964.1 - 0.022 13.9 22.5 0.059 12.5 15.6 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 CEP15964.1 - 0.082 12.6 12.3 0.038 13.7 5.9 2.4 1 1 1 2 2 2 0 Laminin Domain II Peptidase_C6 PF00851.13 CEP15964.1 - 0.099 11.2 5.2 0.18 10.3 3.6 1.4 1 0 0 1 1 1 0 Helper component proteinase WXG100 PF06013.7 CEP15964.1 - 0.11 12.4 5.2 1 9.4 0.1 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG S_100 PF01023.14 CEP15964.1 - 0.14 11.5 3.1 12 5.3 0.2 3.8 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain Tropomyosin_1 PF12718.2 CEP15964.1 - 0.41 10.5 25.7 0.61 9.9 4.5 2.6 1 1 1 2 2 2 0 Tropomyosin like TBPIP PF07106.8 CEP15964.1 - 0.58 9.6 16.2 0.12 11.8 7.9 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 CEP15964.1 - 1.1 9.3 15.5 0.2 11.8 6.7 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 CEP15964.1 - 1.2 9.0 11.0 1.4 8.8 5.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 CEP15964.1 - 1.8 6.2 8.1 3.3 5.4 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CEP15964.1 - 2.1 7.2 23.1 0.11 11.5 10.6 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 CEP15964.1 - 2.4 7.9 6.9 6.5 6.5 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 CEP15964.1 - 3.4 7.4 25.0 0.48 10.2 11.0 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SICA_alpha PF12887.2 CEP15964.1 - 3.5 7.3 8.3 43 3.7 5.8 2.2 1 1 0 1 1 1 0 SICA extracellular alpha domain DUF3450 PF11932.3 CEP15964.1 - 5.4 6.2 15.0 6.3 5.9 9.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.7 CEP15964.1 - 5.9 6.6 26.7 97 2.7 18.4 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.1 CEP15964.1 - 6.1 6.5 15.3 2.1 7.9 7.6 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 CEP15964.1 - 6.9 7.0 19.1 1.9 8.8 1.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 CEP15964.1 - 9.4 6.0 25.7 2 8.2 12.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CEP15964.1 - 9.8 5.7 26.0 57 3.2 18.0 2.2 1 1 0 1 1 1 0 IncA protein AA_kinase PF00696.23 CEP15965.1 - 2.3e-38 132.1 1.0 3.5e-38 131.5 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CEP15965.1 - 1e-14 53.9 0.0 3.7e-14 52.2 0.0 2.0 1 0 0 1 1 1 1 PUA domain AAA PF00004.24 CEP15966.1 - 4e-44 150.0 0.0 1e-43 148.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CEP15966.1 - 2.7e-07 30.6 0.0 5.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CEP15966.1 - 4.1e-07 29.7 0.1 2.7e-06 27.1 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP15966.1 - 2e-06 27.9 0.0 8.7e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CEP15966.1 - 3.7e-06 27.1 0.0 0.00023 21.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP15966.1 - 6.3e-05 22.6 0.1 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CEP15966.1 - 6.4e-05 23.7 0.0 0.00017 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEP15966.1 - 0.0001 21.4 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CEP15966.1 - 0.00037 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CEP15966.1 - 0.00099 17.9 0.0 0.0022 16.7 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CEP15966.1 - 0.0014 18.4 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CEP15966.1 - 0.0015 18.3 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEP15966.1 - 0.0028 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 CEP15966.1 - 0.0033 17.3 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CEP15966.1 - 0.0045 16.6 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CEP15966.1 - 0.0054 15.9 0.1 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CEP15966.1 - 0.0063 15.7 0.0 0.065 12.4 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.1 CEP15966.1 - 0.0077 16.5 0.1 0.031 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CEP15966.1 - 0.0094 15.0 0.0 0.028 13.5 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 CEP15966.1 - 0.016 14.6 0.1 0.068 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CEP15966.1 - 0.016 14.6 0.0 0.092 12.2 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 CEP15966.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CEP15966.1 - 0.024 13.5 0.0 0.052 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CEP15966.1 - 0.032 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 CEP15966.1 - 0.044 13.8 0.0 0.17 11.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CEP15966.1 - 0.046 12.5 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.4 CEP15966.1 - 0.075 12.9 0.3 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NACHT PF05729.7 CEP15966.1 - 0.088 12.4 0.0 0.52 9.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain DUF4208 PF13907.1 CEP15966.1 - 1.2 9.3 4.3 0.38 11.0 0.8 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4208) Tim17 PF02466.14 CEP15967.1 - 2.2e-05 24.4 10.8 2.6e-05 24.2 5.0 2.5 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF2530 PF10745.4 CEP15967.1 - 0.13 12.2 0.3 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) TraT PF05818.7 CEP15967.1 - 1.1 8.5 7.1 0.41 10.0 1.0 2.1 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein FANCI_S1-cap PF14674.1 CEP15967.1 - 1.3 9.1 7.2 6.1 6.9 1.0 2.6 3 0 0 3 3 3 0 FANCI solenoid 1 cap Rick_17kDa_Anti PF05433.10 CEP15967.1 - 2.7 7.7 7.6 1.7 8.3 1.1 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bystin PF05291.6 CEP15968.1 - 2.5e-137 456.8 0.3 2.5e-137 456.8 0.2 1.7 2 0 0 2 2 2 1 Bystin Pkinase PF00069.20 CEP15969.1 - 2.7e-55 187.3 0.1 5e-55 186.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15969.1 - 5.2e-41 140.4 0.0 9.1e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15969.1 - 0.00026 20.0 0.0 0.0082 15.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like OSR1_C PF12202.3 CEP15969.1 - 0.039 13.5 0.2 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C terminal Phlebovirus_NSM PF07246.6 CEP15969.1 - 0.072 12.2 2.4 0.13 11.3 1.6 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Laminin_II PF06009.7 CEP15969.1 - 0.082 12.6 1.6 0.13 11.9 0.3 2.0 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 CEP15969.1 - 0.34 10.7 9.1 0.74 9.6 6.3 1.6 1 0 0 1 1 1 0 Tropomyosin like IncA PF04156.9 CEP15969.1 - 1.7 8.2 5.4 2.8 7.5 3.7 1.3 1 0 0 1 1 1 0 IncA protein Snf7 PF03357.16 CEP15970.1 - 3.9e-16 58.9 11.4 3.9e-16 58.9 7.9 1.7 2 0 0 2 2 2 1 Snf7 DUF4611 PF15387.1 CEP15970.1 - 0.014 15.5 1.3 0.042 13.9 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SLX9 PF15341.1 CEP15970.1 - 0.42 11.0 5.4 0.22 11.9 0.4 2.4 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 Spc24 PF08286.6 CEP15970.1 - 5.9 6.6 11.6 0.56 9.9 2.5 2.9 1 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF336 PF03928.9 CEP15971.1 - 3.8e-25 88.2 0.0 4.7e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) DUF1672 PF07901.6 CEP15971.1 - 0.062 12.2 0.1 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) Solute_trans_a PF03619.11 CEP15972.1 - 0.00027 20.3 0.4 0.00027 20.3 0.3 1.5 2 0 0 2 2 2 1 Organic solute transporter Ostalpha MIG-14_Wnt-bd PF06664.7 CEP15972.1 - 0.057 12.2 0.5 0.078 11.7 0.4 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion ABC_membrane PF00664.18 CEP15973.1 - 1.4e-47 162.3 26.9 5.1e-24 85.1 8.2 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP15973.1 - 2.1e-43 147.9 0.0 3.9e-27 95.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CEP15973.1 - 1.9e-08 33.7 0.4 0.0056 15.9 1.4 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 CEP15973.1 - 2.9e-05 23.1 0.1 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 CEP15973.1 - 5.1e-05 22.7 0.0 0.23 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEP15973.1 - 0.00076 18.9 2.1 0.19 11.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CEP15973.1 - 0.00076 19.8 1.4 0.7 10.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CEP15973.1 - 0.00077 18.9 0.0 0.66 9.4 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.1 CEP15973.1 - 0.00093 19.2 0.3 0.064 13.2 0.1 3.3 3 1 0 3 3 2 1 AAA domain ResIII PF04851.10 CEP15973.1 - 0.0011 18.8 0.1 0.79 9.5 0.0 2.7 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit KaiC PF06745.8 CEP15973.1 - 0.0049 16.0 0.3 0.73 8.9 0.0 2.3 2 0 0 2 2 2 1 KaiC AAA_17 PF13207.1 CEP15973.1 - 0.0063 17.3 0.1 0.29 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CEP15973.1 - 0.017 13.7 0.3 2.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 CEP15973.1 - 0.032 13.1 0.1 0.17 10.7 0.0 2.2 4 0 0 4 4 4 0 NB-ARC domain AAA_10 PF12846.2 CEP15973.1 - 0.039 13.3 0.1 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 CEP15973.1 - 0.056 13.7 0.7 1.8 8.8 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CEP15973.1 - 0.064 13.3 0.5 10 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 CEP15973.1 - 0.068 13.1 5.3 0.47 10.4 0.1 2.9 3 1 0 3 3 2 0 AAA ATPase domain DUF87 PF01935.12 CEP15973.1 - 0.076 12.8 4.1 0.14 11.9 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 CEP15973.1 - 0.11 11.4 0.1 2.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 CEP15973.1 - 0.17 11.0 0.0 15 4.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DEAD PF00270.24 CEP15973.1 - 0.18 11.2 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Fungal_trans PF04082.13 CEP15974.1 - 9.7e-44 149.1 0.2 1.8e-43 148.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain VGCC_beta4Aa_N PF12052.3 CEP15975.1 - 0.11 12.3 0.3 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal GRIM-19 PF06212.7 CEP15976.1 - 1.5e-32 112.0 0.1 1.7e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein zf-RVT PF13966.1 CEP15977.1 - 4.2e-05 23.7 0.5 7.2e-05 23.0 0.3 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Polysacc_lyase PF14099.1 CEP15978.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase bZIP_2 PF07716.10 CEP15979.1 - 5e-09 35.8 8.0 1.3e-08 34.5 5.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP15979.1 - 3.5e-07 30.0 6.4 6.9e-07 29.1 4.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor Spc42p PF11544.3 CEP15979.1 - 0.032 14.1 4.0 0.081 12.8 2.8 1.7 1 0 0 1 1 1 0 Spindle pole body component Spc42p NYD-SP28_assoc PF14775.1 CEP15979.1 - 0.15 11.7 0.9 0.38 10.4 0.6 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF904 PF06005.7 CEP15979.1 - 0.36 11.1 5.1 0.78 10.0 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) NOA36 PF06524.7 CEP15979.1 - 0.63 9.2 6.0 0.94 8.6 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein Tom22 PF04281.8 CEP15979.1 - 1.2 8.7 9.3 0.37 10.3 4.0 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF4611 PF15387.1 CEP15979.1 - 1.6 8.9 7.8 0.37 10.9 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 CEP15979.1 - 3.6 7.0 11.9 0.15 11.6 4.2 1.7 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CEP15979.1 - 4.2 7.6 11.4 0.92 9.7 5.0 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyco_hydro_45 PF02015.11 CEP15980.1 - 2.2e-89 298.8 20.3 2.2e-89 298.8 14.1 2.7 2 1 0 3 3 3 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 CEP15980.1 - 6.5e-18 64.0 32.3 6e-11 41.8 8.4 3.8 4 0 0 4 4 4 2 Fungal cellulose binding domain MAP65_ASE1 PF03999.7 CEP15980.1 - 5.3 5.5 12.6 6.8 5.1 8.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Dicty_REP PF05086.7 CEP15980.1 - 8.6 3.9 12.7 12 3.5 8.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Catalase PF00199.14 CEP15981.1 - 2.9e-154 513.4 0.1 5.9e-154 512.3 0.0 1.5 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.7 CEP15981.1 - 1.1e-17 63.6 0.1 2.2e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF4066 PF13278.1 CEP15981.1 - 0.035 13.3 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative amidotransferase CcmE PF03100.10 CEP15981.1 - 0.082 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 CcmE DJ-1_PfpI PF01965.19 CEP15981.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Phage_TAC PF06222.6 CEP15981.1 - 0.13 11.8 0.2 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone Sec23_trunk PF04811.10 CEP15982.1 - 1e-61 208.4 0.1 1.7e-61 207.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CEP15982.1 - 4e-20 71.1 0.0 8.2e-20 70.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CEP15982.1 - 6e-16 58.7 0.1 2e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CEP15982.1 - 5.9e-15 54.5 6.3 1.2e-14 53.5 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CEP15982.1 - 2.5e-10 39.8 0.0 1e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat VWA_2 PF13519.1 CEP15982.1 - 0.031 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Host_attach PF10116.4 CEP15983.1 - 0.44 10.7 4.3 8.8 6.5 0.2 2.3 2 0 0 2 2 2 0 Protein required for attachment to host cells zf-C2H2_2 PF12756.2 CEP15983.1 - 3.7 7.7 7.8 1.2 9.2 0.9 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RapA_C PF12137.3 CEP15985.1 - 0.0022 16.8 8.4 0.007 15.2 5.8 1.7 1 1 0 1 1 1 1 RNA polymerase recycling family C-terminal MazG PF03819.12 CEP15985.1 - 0.048 13.6 0.6 0.048 13.6 0.4 2.3 2 1 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Mmp37 PF09139.6 CEP15985.1 - 0.054 12.5 4.6 0.067 12.2 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 RsbRD_N PF14361.1 CEP15985.1 - 0.085 13.3 1.9 1.3 9.5 0.1 2.3 1 1 1 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain ASL_C2 PF14698.1 CEP15985.1 - 0.32 11.0 2.1 1.2 9.3 0.3 2.5 1 1 0 2 2 2 0 Argininosuccinate lyase C-terminal KMP11 PF03037.11 CEP15985.1 - 0.36 11.4 12.4 2 9.0 4.7 2.4 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Atg14 PF10186.4 CEP15985.1 - 0.57 9.0 11.3 0.71 8.7 7.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ARGLU PF15346.1 CEP15985.1 - 0.9 9.3 21.7 0.034 13.9 9.5 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 ASD2 PF08687.6 CEP15985.1 - 1.5 8.0 16.4 1.7 7.9 10.3 1.8 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 OmpH PF03938.9 CEP15985.1 - 4.1 7.3 21.3 0.18 11.7 11.0 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GvpL_GvpF PF06386.6 CEP15985.1 - 4.2 6.8 14.1 0.84 9.1 6.5 2.1 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF651 PF04895.7 CEP15985.1 - 6.5 6.4 7.8 3.4 7.3 1.6 2.8 1 1 2 3 3 3 0 Archaeal protein of unknown function (DUF651) Peptidase_S8 PF00082.17 CEP15986.1 - 5.9e-53 179.8 1.4 1.9e-52 178.1 0.3 2.0 2 0 0 2 2 2 1 Subtilase family PA PF02225.17 CEP15986.1 - 7.2e-15 54.5 0.0 2e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 CEP15986.1 - 7.4e-06 26.3 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) FixG_C PF11614.3 CEP15986.1 - 0.079 13.0 0.1 0.24 11.5 0.0 1.7 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Hexapep PF00132.19 CEP15987.1 - 1.1e-10 40.5 17.0 1.8e-07 30.3 2.0 4.3 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CEP15987.1 - 0.00052 19.5 17.2 0.0024 17.4 2.0 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 CEP15987.1 - 0.00095 17.8 0.1 0.0013 17.3 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase Pkinase PF00069.20 CEP15988.1 - 1.3e-64 217.8 0.0 1.8e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15988.1 - 9.3e-28 96.9 0.0 1.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP15988.1 - 0.00097 18.9 0.0 0.079 12.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP15988.1 - 0.019 13.9 0.0 0.047 12.6 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Dicty_REP PF05086.7 CEP15988.1 - 3 5.5 9.8 4.1 5.0 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box PF00646.28 CEP15989.1 - 9.7e-06 25.1 0.0 4.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 F-box domain EF-hand_6 PF13405.1 CEP15989.1 - 7.4e-05 22.3 0.2 0.00027 20.5 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CEP15989.1 - 0.00038 19.6 2.1 0.00094 18.4 1.5 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CEP15989.1 - 0.00073 18.6 1.0 0.0024 17.0 0.7 1.9 1 0 0 1 1 1 1 EF hand TPR_16 PF13432.1 CEP15989.1 - 0.00081 19.9 0.0 0.0046 17.5 0.0 2.2 3 0 0 3 3 2 1 Tetratricopeptide repeat EF-hand_7 PF13499.1 CEP15989.1 - 0.00085 19.4 0.1 0.0038 17.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair F-box-like PF12937.2 CEP15989.1 - 0.00093 18.8 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Apc3 PF12895.2 CEP15989.1 - 0.0081 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CEP15989.1 - 0.012 15.4 0.0 0.038 13.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP15989.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat EF_assoc_1 PF08355.7 CEP15989.1 - 0.027 13.7 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 EF hand associated EF-hand_8 PF13833.1 CEP15989.1 - 0.042 13.4 0.1 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair Elongin_A PF06881.6 CEP15989.1 - 0.042 14.2 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TPR_11 PF13414.1 CEP15989.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 TPR repeat PWI PF01480.12 CEP15990.1 - 6.1e-11 42.2 0.3 1.7e-10 40.8 0.2 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 CEP15990.1 - 1.9e-08 33.7 0.0 7e-08 31.9 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP15990.1 - 0.055 13.4 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CEP15991.1 - 7.8e-59 198.9 0.0 9.3e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15991.1 - 4.3e-23 81.7 0.0 7.5e-23 80.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP15991.1 - 2.1e-07 30.1 0.0 3.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CEP15991.1 - 0.019 14.7 0.0 0.096 12.3 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family AMMECR1 PF01871.12 CEP15991.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 AMMECR1 Kdo PF06293.9 CEP15991.1 - 0.064 12.3 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CEP15991.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NPV_P10 PF05531.7 CEP15992.1 - 1.1 9.6 16.2 6.8 7.0 0.1 5.5 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.10 CEP15992.1 - 2.7 7.1 43.3 0.41 9.7 8.3 3.7 2 2 1 3 3 3 0 Exonuclease VII, large subunit F-box-like PF12937.2 CEP15993.1 - 3.5e-07 29.8 0.2 1e-06 28.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP15993.1 - 0.026 14.1 0.1 0.1 12.2 0.0 2.0 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.1 CEP15993.1 - 0.51 10.1 9.0 3.3 7.5 0.2 4.1 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CEP15993.1 - 1.2 8.7 11.9 5.5 6.7 0.8 4.6 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DDE_1 PF03184.14 CEP15995.1 - 0.044 12.9 1.0 0.074 12.1 0.2 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease Pkinase PF00069.20 CEP15997.1 - 2.8e-56 190.5 0.0 5e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP15997.1 - 3.2e-20 72.2 0.1 6.4e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP15997.1 - 0.0088 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 CEP15997.1 - 0.03 13.5 1.8 0.052 12.7 1.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Zn_clus PF00172.13 CEP15998.1 - 3e-16 59.0 28.9 4.1e-08 33.0 6.9 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 CEP15999.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEA PF01285.13 CEP16000.1 - 4.1e-35 121.7 6.0 4.1e-35 121.7 4.2 2.6 2 1 1 3 3 3 2 TEA/ATTS domain family DUF3884 PF13024.1 CEP16001.1 - 0.077 12.4 0.3 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) DUF639 PF04842.7 CEP16001.1 - 0.11 10.6 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) CotH PF08757.6 CEP16002.1 - 3.1e-37 128.5 1.8 5.2e-37 127.8 1.2 1.3 1 0 0 1 1 1 1 CotH protein Isochorismatase PF00857.15 CEP16003.1 - 6e-22 78.3 0.0 1.1e-21 77.4 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Tetraspannin PF00335.15 CEP16004.1 - 5.2e-05 22.6 11.7 0.00014 21.1 6.9 2.0 2 0 0 2 2 2 1 Tetraspanin family WD40 PF00400.27 CEP16005.1 - 1.2e-37 126.4 21.2 8.8e-07 28.5 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_3 PF13570.1 CEP16005.1 - 0.00014 22.0 0.1 10 6.5 0.0 5.3 5 2 1 6 6 6 2 PQQ-like domain Nup160 PF11715.3 CEP16005.1 - 0.018 13.2 9.3 1.9 6.5 0.6 3.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Acetyltransf_7 PF13508.1 CEP16006.1 - 2.5e-08 33.9 0.0 4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP16006.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP16006.1 - 0.00042 20.4 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP16006.1 - 0.013 15.4 0.0 0.03 14.1 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP16006.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein YjbR PF04237.8 CEP16006.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 YjbR EF-hand_4 PF12763.2 CEP16007.1 - 0.03 14.0 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Tim17 PF02466.14 CEP16008.1 - 7.4e-09 35.7 1.3 1.2e-08 35.0 0.2 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Na_H_Exchanger PF00999.16 CEP16008.1 - 0.12 10.9 0.1 0.21 10.0 0.1 1.4 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Calici_MSP PF05752.6 CEP16009.1 - 0.021 14.4 0.9 0.021 14.4 0.6 2.3 2 0 0 2 2 2 0 Calicivirus minor structural protein BAF1_ABF1 PF04684.8 CEP16009.1 - 5.2 5.7 15.9 0.085 11.6 5.8 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor HEAT PF02985.17 CEP16010.1 - 4.8e-05 23.0 0.1 0.18 11.9 0.0 3.2 2 0 0 2 2 2 2 HEAT repeat UVR PF02151.14 CEP16010.1 - 0.00049 19.5 0.7 0.00049 19.5 0.5 2.5 2 0 0 2 2 2 1 UvrB/uvrC motif HEAT_2 PF13646.1 CEP16010.1 - 0.0084 16.3 0.3 3.5 7.9 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats Med3 PF11593.3 CEP16010.1 - 0.16 11.2 13.5 0.016 14.5 5.8 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal zf-TFIIB PF13453.1 CEP16010.1 - 1.6 7.9 5.2 7.4 5.8 3.6 2.2 1 1 0 1 1 1 0 Transcription factor zinc-finger PPR_2 PF13041.1 CEP16011.1 - 8e-59 195.4 23.1 2.8e-09 36.7 0.5 10.3 8 3 3 11 11 11 10 PPR repeat family PPR_3 PF13812.1 CEP16011.1 - 5.6e-38 126.0 12.0 0.00044 20.3 0.0 10.5 12 0 0 12 12 12 9 Pentatricopeptide repeat domain PPR PF01535.15 CEP16011.1 - 3.7e-33 111.1 30.5 9.6e-06 25.2 0.0 11.8 13 0 0 13 13 13 7 PPR repeat PPR_1 PF12854.2 CEP16011.1 - 1.6e-20 72.2 14.6 1.8e-08 33.7 0.0 9.9 11 0 0 11 11 11 3 PPR repeat TPR_19 PF14559.1 CEP16011.1 - 0.00072 19.8 0.2 1.8 8.9 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.12 CEP16011.1 - 0.0014 18.9 0.4 13 6.1 0.0 4.2 4 0 0 4 4 4 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 CEP16011.1 - 0.0018 17.4 0.0 1.2 8.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP16011.1 - 0.0023 18.3 0.1 60 4.6 0.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat Brix PF04427.13 CEP16012.1 - 2.4e-40 138.2 0.3 3.5e-40 137.7 0.2 1.2 1 0 0 1 1 1 1 Brix domain Metallophos PF00149.23 CEP16013.1 - 0.0011 18.3 0.2 0.0017 17.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP16013.1 - 0.057 13.2 0.1 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Fungal_trans PF04082.13 CEP16014.1 - 1.5e-24 86.3 5.3 2.5e-24 85.5 3.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP16014.1 - 0.38 10.7 10.7 0.78 9.7 7.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WRKY PF03106.10 CEP16015.1 - 5.5e-06 26.1 3.4 1e-05 25.2 2.3 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.11 CEP16015.1 - 0.034 14.0 0.4 0.071 13.0 0.3 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Ribosomal_L13e PF01294.13 CEP16016.1 - 2.4e-77 258.4 5.4 3.9e-77 257.7 3.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e G_glu_transpept PF01019.16 CEP16017.1 - 3.9e-138 461.1 0.0 4.4e-138 460.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Gly_transf_sug PF04488.10 CEP16021.1 - 5.8e-10 39.4 0.1 2.5e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Laminin_G_3 PF13385.1 CEP16021.1 - 8e-08 32.6 0.5 1.6e-07 31.7 0.4 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TcdA_TcdB PF12919.2 CEP16021.1 - 2.1e-05 23.2 0.0 4.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 CEP16021.1 - 0.0018 17.4 0.0 0.0037 16.4 0.0 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Pex14_N PF04695.8 CEP16021.1 - 0.2 11.6 1.9 0.35 10.9 1.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1237 PF06824.6 CEP16022.1 - 1.5e-146 488.3 0.0 1.7e-146 488.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) MFS_1 PF07690.11 CEP16023.1 - 1.4e-32 112.7 21.4 2.6e-30 105.3 14.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CEP16023.1 - 0.018 15.0 0.2 0.018 15.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) p12I PF12233.3 CEP16023.1 - 2.6 8.3 8.5 0.91 9.8 0.1 3.4 3 1 0 3 3 3 0 Human adult T cell leukemia/lymphoma virus protein Porin_3 PF01459.17 CEP16024.1 - 3.2e-55 187.3 0.1 3.5e-55 187.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Tubulin PF00091.20 CEP16025.1 - 1.5e-72 243.9 0.0 1.9e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEP16025.1 - 4.2e-48 162.5 0.0 6.7e-48 161.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CEP16025.1 - 0.00041 19.8 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Motile_Sperm PF00635.21 CEP16026.1 - 1.1e-25 89.3 0.9 2e-25 88.5 0.1 1.8 1 1 1 2 2 2 1 MSP (Major sperm protein) domain Pox_A_type_inc PF04508.7 CEP16026.1 - 0.039 13.7 2.3 0.084 12.6 1.6 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Mitofilin PF09731.4 CEP16026.1 - 0.81 8.2 11.5 1.1 7.7 7.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.8 CEP16026.1 - 1.1 9.0 14.0 1.5 8.5 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IL1_propep PF02394.11 CEP16028.1 - 0.05 13.9 1.6 0.059 13.7 1.1 1.1 1 0 0 1 1 1 0 Interleukin-1 propeptide MBOAT PF03062.14 CEP16029.1 - 1.1e-37 129.8 9.7 1.1e-37 129.8 6.7 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PQQ_2 PF13360.1 CEP16030.1 - 7.9e-16 58.2 0.3 7.6e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 CEP16030.1 - 6.5e-12 44.3 4.0 0.015 14.8 0.0 4.3 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_3 PF13570.1 CEP16030.1 - 3.9e-09 36.4 4.6 0.015 15.5 0.0 5.4 5 0 0 5 5 5 2 PQQ-like domain SH3_1 PF00018.23 CEP16031.1 - 8.2e-12 44.3 0.1 8.2e-12 44.3 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CEP16031.1 - 6.4e-10 38.3 0.4 1.8e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CEP16031.1 - 2.4e-08 33.4 0.0 4.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mito_carr PF00153.22 CEP16032.1 - 7.9e-78 256.2 0.4 7.9e-25 86.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 CEP16032.1 - 4.7e-05 22.9 1.0 0.00067 19.3 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CEP16032.1 - 6.6e-05 21.9 0.1 0.00074 18.6 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CEP16032.1 - 0.00012 22.1 0.5 0.00025 21.1 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CEP16032.1 - 0.0029 16.8 0.2 0.0058 15.9 0.2 1.5 1 0 0 1 1 1 1 EF hand WD40 PF00400.27 CEP16033.1 - 1.8e-24 84.6 8.5 9e-09 34.8 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Rax2 PF12768.2 CEP16033.1 - 3.4e-06 26.4 0.8 6.1e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 Cortical protein marker for cell polarity eIF2A PF08662.6 CEP16033.1 - 0.078 12.6 0.2 2 8.0 0.0 2.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 CEP16033.1 - 0.11 11.8 0.0 2.4 7.4 0.0 2.7 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain rve PF00665.21 CEP16034.1 - 1.5e-15 57.3 0.0 2.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP16034.1 - 0.0011 18.4 0.0 0.0037 16.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CEP16034.1 - 0.099 12.6 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 DDE domain PapB PF03333.8 CEP16035.1 - 0.047 13.5 0.4 0.27 11.0 0.0 2.3 3 0 0 3 3 3 0 Adhesin biosynthesis transcription regulatory protein SET PF00856.23 CEP16037.1 - 1.8e-10 41.3 0.0 4.8e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 SET domain Pkinase PF00069.20 CEP16038.1 - 0.00079 18.6 0.0 0.00079 18.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Med15 PF09606.5 CEP16038.1 - 0.0062 14.8 48.2 0.0082 14.3 33.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAM2 PF07145.10 CEP16038.1 - 0.014 14.8 1.6 0.031 13.7 1.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region SprA-related PF12118.3 CEP16038.1 - 0.02 14.2 27.2 0.032 13.5 18.9 1.2 1 0 0 1 1 1 0 SprA-related family DUF4557 PF15101.1 CEP16038.1 - 0.062 13.1 16.3 0.11 12.3 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TFIIA PF03153.8 CEP16038.1 - 0.21 11.4 25.3 0.35 10.7 17.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_PP31 PF05311.6 CEP16038.1 - 0.4 9.9 10.3 0.7 9.1 7.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) EIIBC-GUT_N PF03612.9 CEP16038.1 - 3.9 7.0 7.2 7.8 6.0 5.0 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus OATP PF03137.15 CEP16038.1 - 5.6 4.8 7.1 8.3 4.3 5.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FLO_LFY PF01698.11 CEP16038.1 - 6.4 5.5 11.1 10 4.8 7.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PAT1 PF09770.4 CEP16038.1 - 6.6 4.8 52.1 9.8 4.2 36.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 CEP16038.1 - 7.3 6.2 11.2 13 5.4 7.7 1.3 1 0 0 1 1 1 0 AUX/IAA family Transposase_21 PF02992.9 CEP16043.1 - 1.8e-08 33.7 0.2 3.4e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 Caps_synth_CapC PF14102.1 CEP16043.1 - 0.17 11.9 0.0 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 Capsule biosynthesis CapC GAGA PF09237.6 CEP16044.1 - 0.038 13.5 2.3 0.055 13.0 1.6 1.3 1 0 0 1 1 1 0 GAGA factor Herpes_U59 PF04529.7 CEP16045.1 - 0.043 12.6 0.1 0.048 12.4 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus U59 protein DUF4218 PF13960.1 CEP16046.1 - 0.00028 20.3 0.3 0.00033 20.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RVT_1 PF00078.22 CEP16048.1 - 1.3e-15 57.3 0.0 2.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP16050.1 - 4.1e-07 29.5 0.0 1.3e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tropomyosin_1 PF12718.2 CEP16051.1 - 3.8e-29 101.3 40.3 3.8e-29 101.3 27.9 1.7 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 CEP16051.1 - 7.5e-07 28.4 37.5 6.2e-06 25.4 26.0 2.1 1 1 0 1 1 1 1 Tropomyosin PspA_IM30 PF04012.7 CEP16051.1 - 5.8e-06 25.8 30.1 1e-05 24.9 20.3 1.8 1 1 0 1 1 1 1 PspA/IM30 family Myosin_tail_1 PF01576.14 CEP16051.1 - 2.2e-05 22.4 38.0 0.00045 18.1 26.3 2.0 1 1 0 1 1 1 1 Myosin tail Laminin_II PF06009.7 CEP16051.1 - 3.1e-05 23.7 26.7 0.00054 19.7 10.2 2.4 1 1 1 2 2 2 1 Laminin Domain II Rootletin PF15035.1 CEP16051.1 - 3.1e-05 24.0 33.8 0.003 17.5 11.9 3.1 1 1 2 3 3 3 2 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 CEP16051.1 - 4.5e-05 23.3 39.0 0.001 18.9 8.4 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 CEP16051.1 - 0.00016 21.4 38.0 0.00021 21.0 23.6 2.0 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 CEP16051.1 - 0.00017 21.5 36.4 0.033 14.0 13.6 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) HR1 PF02185.11 CEP16051.1 - 0.00023 20.8 32.4 0.024 14.3 1.2 4.5 1 1 3 4 4 4 2 Hr1 repeat MscS_porin PF12795.2 CEP16051.1 - 0.00024 20.5 22.5 0.00024 20.5 15.6 2.0 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain ADIP PF11559.3 CEP16051.1 - 0.00024 21.0 37.0 0.0051 16.7 6.9 3.0 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 CEP16051.1 - 0.00035 20.3 50.1 0.083 12.7 10.0 3.3 1 1 2 3 3 3 3 TATA element modulatory factor 1 DNA binding Nup54 PF13874.1 CEP16051.1 - 0.00087 18.9 24.3 0.0024 17.5 8.2 2.2 1 1 0 2 2 2 1 Nucleoporin complex subunit 54 BRE1 PF08647.6 CEP16051.1 - 0.00095 19.1 34.5 0.017 15.1 9.2 2.1 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase Lectin_N PF03954.9 CEP16051.1 - 0.0011 18.3 6.2 0.0011 18.3 4.3 2.6 1 1 2 3 3 3 1 Hepatic lectin, N-terminal domain CALCOCO1 PF07888.6 CEP16051.1 - 0.0033 15.7 27.5 0.0058 14.9 7.8 2.0 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like Striatin PF08232.7 CEP16051.1 - 0.0034 17.6 15.3 0.0034 17.6 10.6 2.1 1 1 1 2 2 2 1 Striatin family AAA_13 PF13166.1 CEP16051.1 - 0.0039 15.7 31.8 0.0058 15.1 22.0 1.3 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 CEP16051.1 - 0.0043 16.5 29.8 0.11 11.9 11.1 2.1 1 1 1 2 2 2 1 Intermediate filament protein Lebercilin PF15619.1 CEP16051.1 - 0.0047 16.3 37.9 0.029 13.8 26.0 2.3 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Reo_sigmaC PF04582.7 CEP16051.1 - 0.0062 15.7 7.4 0.019 14.1 4.0 1.9 1 1 1 2 2 2 1 Reovirus sigma C capsid protein IncA PF04156.9 CEP16051.1 - 0.0082 15.7 36.6 0.14 11.7 7.4 2.2 1 1 1 2 2 2 2 IncA protein Spc7 PF08317.6 CEP16051.1 - 0.0096 14.6 33.3 0.014 14.0 21.8 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein APG6 PF04111.7 CEP16051.1 - 0.013 14.5 39.0 0.036 13.1 10.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4201 PF13870.1 CEP16051.1 - 0.013 14.9 33.6 1.9 7.8 11.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF904 PF06005.7 CEP16051.1 - 0.018 15.3 45.8 0.045 14.0 3.7 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF904) GAS PF13851.1 CEP16051.1 - 0.022 13.9 37.8 0.087 12.0 25.4 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding WXG100 PF06013.7 CEP16051.1 - 0.024 14.6 16.6 0.52 10.3 2.7 4.1 2 2 1 3 3 3 0 Proteins of 100 residues with WXG KLRAQ PF10205.4 CEP16051.1 - 0.025 14.6 26.9 0.42 10.6 6.2 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein TBPIP PF07106.8 CEP16051.1 - 0.027 14.0 36.2 0.057 12.9 9.7 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LPP PF04728.8 CEP16051.1 - 0.035 13.9 6.2 4 7.3 1.4 3.8 2 2 1 3 3 3 0 Lipoprotein leucine-zipper Cep57_CLD_2 PF14197.1 CEP16051.1 - 0.038 13.9 36.7 0.18 11.7 1.1 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 EzrA PF06160.7 CEP16051.1 - 0.038 12.1 29.5 0.099 10.8 20.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3584 PF12128.3 CEP16051.1 - 0.043 11.1 33.5 0.14 9.4 23.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2514 PF10721.4 CEP16051.1 - 0.05 13.3 8.4 0.31 10.7 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) DUF869 PF05911.6 CEP16051.1 - 0.18 10.0 32.7 0.78 7.8 13.5 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF3450 PF11932.3 CEP16051.1 - 0.2 10.9 27.3 0.11 11.8 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 CEP16051.1 - 0.27 11.5 30.6 0.41 11.0 6.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CtIP_N PF10482.4 CEP16051.1 - 0.29 10.9 26.4 4.1 7.2 5.9 2.6 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain SH3BP5 PF05276.9 CEP16051.1 - 0.3 10.3 21.7 0.74 9.0 2.0 2.4 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Taxilin PF09728.4 CEP16051.1 - 0.3 10.1 33.8 1.3 7.9 23.4 2.3 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF1664 PF07889.7 CEP16051.1 - 0.35 10.6 22.7 0.49 10.1 4.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) WEMBL PF05701.6 CEP16051.1 - 0.43 8.9 35.8 0.77 8.1 2.4 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Syntaxin-6_N PF09177.6 CEP16051.1 - 0.51 10.7 23.6 0.11 12.9 3.4 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 CEP16051.1 - 0.54 10.3 21.7 25 4.9 14.0 2.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4164 PF13747.1 CEP16051.1 - 0.58 10.3 30.6 0.11 12.6 5.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) SlyX PF04102.7 CEP16051.1 - 0.72 10.2 27.2 1.3 9.4 5.4 3.2 1 1 2 3 3 3 0 SlyX AAA_27 PF13514.1 CEP16051.1 - 0.73 7.4 26.9 0.98 7.0 18.7 1.3 1 0 0 1 1 1 0 AAA domain Laminin_I PF06008.9 CEP16051.1 - 0.93 8.7 31.8 1.7 7.9 22.0 1.4 1 1 0 1 1 1 0 Laminin Domain I DUF948 PF06103.6 CEP16051.1 - 1 9.2 18.0 2.5 8.0 2.6 2.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 CEP16051.1 - 1.1 9.5 22.4 0.82 9.9 3.6 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 CEP16051.1 - 1.6 9.2 25.6 1.5e+04 -10.3 17.6 3.5 1 1 0 1 1 0 0 N-terminal domain of unknown function (DUF4140) IFT57 PF10498.4 CEP16051.1 - 1.8 7.2 31.3 22 3.6 21.7 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF812 PF05667.6 CEP16051.1 - 1.8 6.9 30.3 2.2 6.6 21.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Atg14 PF10186.4 CEP16051.1 - 1.9 7.3 31.2 9.3 5.0 11.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 CEP16051.1 - 2.2 8.2 29.9 0.99 9.3 3.0 4.7 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) HOOK PF05622.7 CEP16051.1 - 2.4 5.8 34.1 6.5 4.4 23.7 1.7 1 1 0 1 1 1 0 HOOK protein DivIVA PF05103.8 CEP16051.1 - 2.5 8.1 32.8 2.1 8.3 11.9 2.8 1 1 1 2 2 2 0 DivIVA protein Nsp1_C PF05064.8 CEP16051.1 - 2.7 7.6 26.0 4.7 6.8 5.4 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region PEARLI-4 PF05278.7 CEP16051.1 - 2.8 7.2 26.6 5.5 6.2 2.4 2.4 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) TMCO5 PF14992.1 CEP16051.1 - 2.8 6.9 33.4 0.92 8.5 11.6 2.1 1 1 1 2 2 2 0 TMCO5 family DUF2968 PF11180.3 CEP16051.1 - 2.9 7.2 22.5 3 7.1 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) HemX PF04375.9 CEP16051.1 - 3.7 6.0 25.0 1.1 7.7 4.3 2.2 1 1 1 2 2 2 0 HemX FliJ PF02050.11 CEP16051.1 - 4 7.5 30.4 1.3 9.1 6.7 3.0 1 1 2 3 3 3 0 Flagellar FliJ protein Uds1 PF15456.1 CEP16051.1 - 4.1 7.4 26.4 9.3 6.2 0.7 3.0 1 1 2 3 3 3 0 Up-regulated During Septation Occludin_ELL PF07303.8 CEP16051.1 - 4.2 8.1 21.3 2.2 9.0 2.6 2.8 1 1 1 2 2 2 0 Occludin homology domain CENP-H PF05837.7 CEP16051.1 - 4.4 7.5 30.8 3.9 7.6 4.7 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PIG-S PF10510.4 CEP16051.1 - 4.4 5.8 13.1 5.3 5.6 9.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF4407 PF14362.1 CEP16051.1 - 4.4 6.1 23.4 5.6 5.8 16.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.4 CEP16051.1 - 5.1 7.3 29.0 10 6.3 0.5 3.8 1 1 2 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.4 CEP16051.1 - 5.3 7.2 19.5 6.1 7.0 5.3 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CDC37_N PF03234.9 CEP16051.1 - 5.3 7.3 28.7 20 5.4 19.9 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DivIC PF04977.10 CEP16051.1 - 5.4 6.5 38.8 0.72 9.3 5.8 4.0 1 1 3 4 4 4 0 Septum formation initiator MAD PF05557.8 CEP16051.1 - 5.4 4.9 36.7 8.6 4.3 16.9 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein ALMT PF11744.3 CEP16051.1 - 5.5 5.5 9.2 7.5 5.0 6.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4391 PF14335.1 CEP16051.1 - 5.6 6.2 26.4 2 7.7 13.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4391) AHS1 PF02682.11 CEP16051.1 - 5.6 6.3 8.4 3.2 7.1 2.4 2.1 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 Syntaxin PF00804.20 CEP16051.1 - 6 7.0 31.0 11 6.2 6.4 2.2 1 1 1 2 2 2 0 Syntaxin SSFA2_C PF14723.1 CEP16051.1 - 6.1 6.5 12.9 7.8 6.1 9.0 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF724 PF05266.9 CEP16051.1 - 6.4 6.3 31.8 6.5 6.3 10.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Mnd1 PF03962.10 CEP16051.1 - 6.4 6.3 33.6 25 4.4 11.9 2.3 1 1 1 2 2 2 0 Mnd1 family DUF4200 PF13863.1 CEP16051.1 - 6.9 6.6 40.6 4.1 7.3 14.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Rad21_Rec8_N PF04825.8 CEP16051.1 - 7.5 6.5 6.6 5.1 7.0 0.5 2.5 1 1 1 2 2 2 0 N terminus of Rad21 / Rec8 like protein DUF641 PF04859.7 CEP16051.1 - 7.8 6.2 21.8 26 4.5 7.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.15 CEP16051.1 - 8 6.2 40.8 3.7 7.3 2.7 4.2 1 1 3 4 4 4 0 Prefoldin subunit EAP30 PF04157.11 CEP16051.1 - 9 5.3 22.5 0.57 9.3 5.8 2.6 1 1 2 3 3 3 0 EAP30/Vps36 family DASH_Hsk3 PF08227.6 CEP16051.1 - 9.6 6.4 11.2 42 4.4 0.7 4.1 3 1 1 4 4 4 0 DASH complex subunit Hsk3 like Snapin_Pallidin PF14712.1 CEP16051.1 - 9.7 6.5 29.3 31 4.9 8.5 3.7 1 1 2 3 3 3 0 Snapin/Pallidin Ycf1 PF05758.7 CEP16051.1 - 9.8 3.7 18.5 11 3.6 12.8 1.0 1 0 0 1 1 1 0 Ycf1 Ribosomal_L37ae PF01780.14 CEP16052.1 - 1e-40 137.4 11.3 1.1e-40 137.3 7.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 CEP16052.1 - 0.00066 19.4 2.3 0.00096 18.9 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CEP16052.1 - 0.0012 18.1 3.3 0.55 9.7 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 CEP16052.1 - 0.016 14.8 2.6 0.3 10.7 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif OrfB_Zn_ribbon PF07282.6 CEP16052.1 - 0.075 12.6 1.5 0.11 12.2 1.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.1 CEP16052.1 - 0.092 13.0 2.0 1.7 9.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 CEP16052.1 - 0.15 12.0 2.0 0.78 9.7 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 CEP16052.1 - 0.22 11.0 0.9 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Elf1 PF05129.8 CEP16052.1 - 0.23 11.1 3.0 0.41 10.3 2.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 CEP16052.1 - 0.26 11.0 6.2 0.25 11.1 0.6 2.3 1 1 1 2 2 2 0 BED zinc finger C1_1 PF00130.17 CEP16052.1 - 0.34 10.6 2.9 0.49 10.1 2.0 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CarbpepA_inh PF02977.10 CEP16052.1 - 1.7 8.2 5.4 8.5 6.0 3.7 2.0 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 CEP16052.1 - 2.3 8.7 4.5 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Kelch_4 PF13418.1 CEP16053.1 - 1.6e-26 91.8 7.3 2.1e-10 40.2 0.1 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP16053.1 - 1.1e-24 85.9 3.4 1.5e-05 24.8 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CEP16053.1 - 3.8e-20 71.1 6.1 5e-05 23.2 0.0 5.6 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.1 CEP16053.1 - 2.7e-19 68.7 2.1 0.00021 21.3 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP16053.1 - 1.4e-17 62.6 0.1 0.0019 17.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CEP16053.1 - 5.2e-15 54.7 1.8 0.00057 19.3 0.4 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 CEP16053.1 - 4e-12 46.1 0.0 7.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 CEP16053.1 - 0.0022 17.8 0.0 0.0066 16.2 0.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Rax2 PF12768.2 CEP16053.1 - 0.0056 15.9 0.0 0.35 10.0 0.0 2.2 1 1 1 2 2 2 2 Cortical protein marker for cell polarity Ribosomal_L29 PF00831.18 CEP16054.1 - 2e-14 53.0 3.1 2e-14 53.0 2.2 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 CEP16054.1 - 0.067 13.4 3.2 0.095 12.9 2.2 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 CENP-B_N PF04218.8 CEP16054.1 - 1 8.8 5.1 16 5.0 0.1 3.1 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain HSP90 PF00183.13 CEP16055.1 - 1.3e-259 862.0 33.5 1.5e-259 861.8 23.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CEP16055.1 - 1.1e-12 47.6 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CEP16055.1 - 2.1e-11 43.6 0.1 2.1e-11 43.6 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.11 CEP16056.1 - 5.5e-15 54.9 32.7 9.9e-15 54.0 3.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.11 CEP16056.1 - 2.8e-10 39.5 15.5 5.9e-10 38.4 6.1 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter Methyltransf_11 PF08241.7 CEP16057.1 - 7.3e-13 48.8 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP16057.1 - 2e-12 47.1 0.0 2.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP16057.1 - 1.4e-11 44.1 0.0 2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP16057.1 - 4.4e-08 33.4 0.0 1.2e-07 31.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP16057.1 - 7.2e-08 32.8 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP16057.1 - 2.8e-06 26.6 0.0 4.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CEP16057.1 - 9.3e-06 26.1 0.0 1.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP16057.1 - 0.00017 20.7 0.0 0.00077 18.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 CEP16057.1 - 0.00031 20.1 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 CEP16057.1 - 0.0022 17.3 0.0 0.0048 16.2 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 CEP16057.1 - 0.026 13.7 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 CEP16057.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CEP16057.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 CEP16057.1 - 0.12 11.9 0.0 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF938 PF06080.7 CEP16057.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Mucin PF01456.12 CEP16057.1 - 0.38 10.5 14.5 0.12 12.1 5.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Acyl-CoA_dh_1 PF00441.19 CEP16058.1 - 5.1e-50 169.4 3.4 8e-50 168.8 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEP16058.1 - 3.5e-25 88.7 0.1 6.3e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CEP16058.1 - 6.6e-22 76.7 0.4 1.7e-21 75.4 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CEP16058.1 - 1.7e-18 67.1 1.0 2.9e-18 66.4 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CEP16058.1 - 2.1e-05 24.0 0.5 6.7e-05 22.4 0.3 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Spc7 PF08317.6 CEP16059.1 - 0.38 9.3 45.2 0.079 11.6 14.7 3.3 1 1 3 4 4 4 0 Spc7 kinetochore protein GSH_synthase PF03199.10 CEP16059.1 - 0.45 10.6 3.0 0.47 10.5 0.5 2.3 2 0 0 2 2 2 0 Eukaryotic glutathione synthase TBPIP PF07106.8 CEP16059.1 - 1.4 8.3 49.4 0.037 13.5 10.6 5.5 1 1 4 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 CEP16059.1 - 1.9 7.6 51.0 0.015 14.5 11.0 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CEP16059.1 - 2 7.3 46.2 0.76 8.7 10.8 3.4 1 1 2 3 3 3 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CEP16059.1 - 3.7 7.2 54.9 2.3 7.9 13.5 4.6 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein HBS1_N PF08938.5 CEP16060.1 - 1e-14 54.4 4.7 1.2e-14 54.1 3.2 1.1 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.22 CEP16061.1 - 1.2e-47 161.8 0.0 2.3e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEP16061.1 - 1.3e-17 63.7 0.0 5.6e-17 61.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CEP16061.1 - 1.8e-06 27.8 0.0 5.7e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CEP16061.1 - 1.6e-05 24.9 0.1 3.7e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CEP16061.1 - 0.00016 21.2 0.1 0.00041 19.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CEP16061.1 - 0.00037 20.9 0.0 0.0057 17.1 0.0 2.7 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 CEP16061.1 - 0.011 15.1 2.1 0.24 10.7 0.0 2.6 3 0 0 3 3 3 0 Ras family DUF2431 PF10354.4 CEP16061.1 - 0.15 12.0 4.4 0.058 13.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) DUF1120 PF06551.7 CEP16061.1 - 0.23 11.7 2.8 0.66 10.3 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Pkinase PF00069.20 CEP16062.1 - 1.4e-19 70.2 0.0 1.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16062.1 - 1.2e-08 34.4 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mem_trans PF03547.13 CEP16063.1 - 1.4e-47 161.8 11.9 1.8e-47 161.4 8.3 1.1 1 0 0 1 1 1 1 Membrane transport protein Dynein_light PF01221.13 CEP16063.1 - 2.4e-32 110.7 1.0 4.6e-32 109.8 0.7 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3464 PF11947.3 CEP16063.1 - 0.056 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2514 PF10721.4 CEP16064.1 - 0.038 13.7 1.5 0.074 12.7 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Chordopox_G3 PF06129.7 CEP16064.1 - 0.084 13.0 0.7 0.32 11.1 0.1 2.0 1 1 1 2 2 2 0 Chordopoxvirus G3 protein FliS PF02561.9 CEP16065.1 - 0.031 14.1 0.6 0.2 11.5 0.1 2.0 1 1 1 2 2 2 0 Flagellar protein FliS DUF3350 PF11830.3 CEP16065.1 - 0.11 12.5 0.2 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) DIOX_N PF14226.1 CEP16066.1 - 2.4e-26 92.5 0.5 4.5e-26 91.6 0.3 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CEP16066.1 - 2.3e-19 69.4 0.0 5.1e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CR6_interact PF10147.4 CEP16067.1 - 0.001 18.4 6.6 0.0015 17.8 4.6 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Nop25 PF09805.4 CEP16067.1 - 0.074 13.1 4.8 0.13 12.3 3.3 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF865 PF05906.6 CEP16067.1 - 0.2 11.2 0.8 0.34 10.5 0.5 1.3 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Ribosomal_L19e PF01280.15 CEP16068.1 - 3.8e-59 198.7 11.0 3.8e-59 198.7 7.7 1.6 1 1 0 1 1 1 1 Ribosomal protein L19e E1_DerP2_DerF2 PF02221.10 CEP16069.1 - 1.1e-05 25.6 0.0 1.3e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 ML domain Yae1_N PF09811.4 CEP16070.1 - 3e-08 33.0 2.2 4e-08 32.6 1.6 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal HisKA_2 PF07568.7 CEP16070.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase Ribosomal_S7 PF00177.16 CEP16071.1 - 3.7e-36 123.9 0.5 4.7e-36 123.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MFS_1 PF07690.11 CEP16072.1 - 2.3e-28 98.9 46.0 2.6e-17 62.5 14.3 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily Kinesin PF00225.18 CEP16073.1 - 1.1e-45 155.8 0.3 2.5e-45 154.6 0.2 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF1212 PF06738.7 CEP16074.1 - 4e-32 111.2 12.8 9.4e-30 103.5 0.5 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CEP16074.1 - 1.1e-19 70.7 23.4 1.1e-18 67.3 6.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Suc_Fer-like PF06999.7 CEP16075.1 - 1.2e-21 77.8 0.0 1.5e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PPR_2 PF13041.1 CEP16076.1 - 4.6e-65 215.4 28.7 4.5e-12 45.7 0.0 9.4 4 1 6 10 10 10 8 PPR repeat family PPR PF01535.15 CEP16076.1 - 3.7e-44 145.6 13.5 1.1e-06 28.2 0.0 11.9 12 0 0 12 12 12 8 PPR repeat PPR_1 PF12854.2 CEP16076.1 - 3.4e-39 132.0 6.3 2.8e-05 23.4 0.0 9.9 10 0 0 10 10 10 9 PPR repeat PPR_3 PF13812.1 CEP16076.1 - 7.6e-34 113.1 1.3 0.00027 20.9 0.0 10.7 11 0 0 11 11 11 7 Pentatricopeptide repeat domain MRP-S27 PF10037.4 CEP16076.1 - 4.5e-05 22.5 0.5 0.00081 18.4 0.1 2.6 2 1 1 3 3 3 1 Mitochondrial 28S ribosomal protein S27 Peptidase_M16 PF00675.15 CEP16076.1 - 0.098 12.4 0.5 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) Zip PF02535.17 CEP16078.1 - 0.59 9.0 14.8 0.088 11.7 4.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter WD40 PF00400.27 CEP16079.1 - 7.6e-68 222.1 32.2 3.7e-12 45.6 0.7 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CEP16079.1 - 4.8e-06 25.9 0.0 0.13 11.7 0.0 4.3 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 CEP16079.1 - 2.9e-05 23.8 4.4 0.0034 17.1 0.1 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CEP16079.1 - 0.16 9.7 12.6 0.3 8.8 0.7 3.1 1 1 2 4 4 4 0 IKI3 family Coatomer_WDAD PF04053.9 CEP16079.1 - 0.17 10.6 4.1 0.47 9.1 0.9 2.5 2 1 1 3 3 3 0 Coatomer WD associated region Citrate_synt PF00285.16 CEP16081.1 - 1.2e-104 349.8 0.0 1.5e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ADH_zinc_N PF00107.21 CEP16081.1 - 0.026 14.0 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase XH PF03469.9 CEP16081.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 XH domain V-ATPase_H_N PF03224.9 CEP16084.1 - 8.8e-59 199.1 8.7 1.1e-37 129.8 0.8 2.7 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 CEP16084.1 - 1.8e-42 144.0 0.8 3.1e-42 143.2 0.1 1.7 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 CEP16084.1 - 0.0053 17.0 0.6 0.078 13.2 0.1 2.8 2 1 0 2 2 2 1 HEAT repeats Arm PF00514.18 CEP16084.1 - 0.013 15.3 0.6 9.2 6.2 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CEP16084.1 - 0.067 13.2 0.0 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat TPR_11 PF13414.1 CEP16085.1 - 2.5e-17 62.2 7.1 9.7e-13 47.5 1.4 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CEP16085.1 - 2.6e-16 58.4 5.6 2.8e-06 26.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP16085.1 - 5.5e-12 44.6 9.5 0.00066 19.3 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEP16085.1 - 2e-10 40.4 8.2 1.8e-06 27.7 0.2 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEP16085.1 - 2.1e-09 37.5 0.7 6.3e-08 32.8 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP16085.1 - 1.2e-08 35.4 1.8 0.00016 22.2 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP16085.1 - 1.2e-07 31.7 5.6 0.00011 22.2 0.7 2.2 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 FKBP_C PF00254.23 CEP16085.1 - 1.7e-07 31.1 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_7 PF13176.1 CEP16085.1 - 2.3e-07 30.1 1.8 0.0085 15.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP16085.1 - 8.4e-07 28.3 7.8 0.014 15.0 1.5 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP16085.1 - 2.7e-06 27.1 0.1 1.9e-05 24.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP16085.1 - 4.2e-06 26.9 0.4 0.0092 16.5 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEP16085.1 - 0.00019 21.2 4.2 0.85 9.5 0.0 3.3 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CEP16085.1 - 0.00046 20.4 3.2 0.044 14.2 0.2 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.9 CEP16085.1 - 0.02 14.0 0.5 0.92 8.6 0.0 2.1 1 1 1 2 2 2 0 Coatomer epsilon subunit MIT PF04212.13 CEP16085.1 - 0.067 13.0 4.2 1.3 8.9 0.3 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 CEP16085.1 - 0.18 11.1 5.5 1.3 8.3 0.1 3.1 2 1 2 4 4 4 0 26S proteasome subunit RPN7 DUF3115 PF11312.3 CEP16086.1 - 0.02 13.7 0.4 0.022 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) DUF520 PF04461.8 CEP16086.1 - 0.03 14.1 1.2 0.04 13.7 0.1 1.7 2 1 0 1 1 1 0 Protein of unknown function (DUF520) Fork_head PF00250.13 CEP16086.1 - 0.19 11.7 1.5 1.5 8.8 0.1 2.4 2 1 0 2 2 2 0 Fork head domain PAP2 PF01569.16 CEP16087.1 - 1.8e-28 98.7 1.9 4.3e-28 97.5 1.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily DUF805 PF05656.9 CEP16087.1 - 0.0014 18.4 0.9 0.52 10.1 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF805) Oleosin PF01277.12 CEP16087.1 - 0.057 12.9 0.2 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Oleosin OppC_N PF12911.2 CEP16087.1 - 2.1 7.7 4.8 0.39 10.1 0.1 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C PAP2_C PF14360.1 CEP16087.1 - 2.5 8.4 8.3 0.21 11.8 0.8 2.7 2 1 1 3 3 3 0 PAP2 superfamily C-terminal PMT PF02366.13 CEP16088.1 - 1.5e-73 247.1 23.8 3.4e-73 246.0 16.5 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEP16088.1 - 6.1e-10 38.9 0.4 5.5e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 MIR domain Choline_kinase PF01633.15 CEP16089.1 - 9.4e-62 208.3 0.0 2.6e-61 206.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CEP16089.1 - 3.5e-19 69.4 0.0 5.4e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CEP16089.1 - 0.00032 19.9 0.1 0.00045 19.4 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Melibiase PF02065.13 CEP16090.1 - 1.1e-09 37.5 1.4 3.9e-09 35.6 0.2 2.1 1 1 0 2 2 2 1 Melibiase DDHD PF02862.12 CEP16091.1 - 1.3e-42 146.1 0.0 1.3e-42 146.1 0.0 3.9 3 2 0 3 3 3 1 DDHD domain WWE PF02825.15 CEP16091.1 - 0.035 13.5 0.4 0.46 9.9 0.0 2.5 1 1 1 2 2 2 0 WWE domain Dala_Dala_lig_N PF01820.16 CEP16091.1 - 7 6.9 6.1 1.5 9.1 0.5 2.6 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Pro_isomerase PF00160.16 CEP16092.1 - 5.5e-50 169.5 1.4 2.5e-49 167.4 0.2 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PIF1 PF05970.9 CEP16092.1 - 3.6e-11 42.6 0.0 6.9e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase Rtf2 PF04641.7 CEP16092.1 - 1.3e-08 34.4 0.4 1.3e-08 34.4 0.3 2.4 2 0 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 CEP16092.1 - 0.0011 18.8 0.1 0.038 13.9 0.0 2.8 1 1 1 2 2 2 1 U-box domain zf-C2H2_4 PF13894.1 CEP16093.1 - 4.8e-13 48.4 20.1 0.0003 20.9 0.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP16093.1 - 2.4e-08 33.8 21.0 0.00079 19.6 0.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP16093.1 - 2.9e-08 33.6 17.6 7.9e-05 22.7 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEP16093.1 - 0.027 14.3 3.5 0.052 13.4 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger NST1 PF13945.1 CEP16093.1 - 0.036 14.1 12.0 0.074 13.1 8.3 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF572 PF04502.8 CEP16093.1 - 0.042 13.0 10.6 0.059 12.5 7.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TAF4 PF05236.9 CEP16093.1 - 0.1 11.8 5.7 0.16 11.2 3.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-Di19 PF05605.7 CEP16093.1 - 0.2 11.7 13.7 0.53 10.4 0.0 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.7 CEP16093.1 - 0.26 11.3 2.6 4.1 7.4 0.2 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain Macoilin PF09726.4 CEP16093.1 - 0.5 8.5 10.1 0.61 8.2 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Ndc1_Nup PF09531.5 CEP16093.1 - 6.5 5.0 6.5 8.1 4.7 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SEP PF08059.8 CEP16094.1 - 9.5e-27 93.1 0.0 2e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CEP16094.1 - 7.4e-17 61.1 0.0 1.5e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CEP16094.1 - 1.9e-14 52.8 0.9 3.2e-14 52.1 0.6 1.4 1 0 0 1 1 1 1 UBA-like domain LEA_2 PF03168.8 CEP16095.1 - 5.2e-06 26.7 0.1 9.3e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF2477 PF10631.4 CEP16095.1 - 0.07 13.3 9.8 0.12 12.6 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) DUF2897 PF11446.3 CEP16095.1 - 0.12 12.2 1.5 0.26 11.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Coq4 PF05019.8 CEP16096.1 - 1.4e-89 298.8 0.0 1.6e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 RPAP2_Rtr1 PF04181.8 CEP16098.1 - 7.4e-21 74.0 1.4 3.1e-20 72.0 0.9 2.2 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF3275 PF11679.3 CEP16098.1 - 0.0023 17.5 1.0 0.0023 17.5 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3275) FixG_C PF11614.3 CEP16098.1 - 0.0098 15.9 5.6 0.027 14.5 0.3 2.5 2 0 0 2 2 2 1 IG-like fold at C-terminal of FixG, putative oxidoreductase CK_II_beta PF01214.13 CEP16099.1 - 7.4e-67 224.4 1.1 2.3e-66 222.7 0.8 1.8 1 1 0 1 1 1 1 Casein kinase II regulatory subunit bZIP_1 PF00170.16 CEP16100.1 - 1.2e-10 41.1 7.8 2.1e-10 40.4 5.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP16100.1 - 6.1e-10 38.7 6.7 6.1e-10 38.7 4.6 1.6 1 1 0 1 1 1 1 Basic region leucine zipper DUF2400 PF09674.5 CEP16100.1 - 0.0014 18.3 0.2 0.0017 18.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) ADIP PF11559.3 CEP16100.1 - 0.0049 16.7 6.3 0.0074 16.2 4.3 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding bZIP_Maf PF03131.12 CEP16100.1 - 0.011 16.0 7.3 0.017 15.4 5.1 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Myosin_tail_1 PF01576.14 CEP16100.1 - 0.015 13.0 3.5 0.019 12.7 2.4 1.0 1 0 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.4 CEP16100.1 - 0.02 14.7 4.3 0.027 14.3 3.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.13 CEP16100.1 - 0.022 14.7 0.3 0.046 13.6 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF2051 PF09738.4 CEP16100.1 - 0.023 13.9 3.4 0.029 13.6 2.4 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) EMP24_GP25L PF01105.19 CEP16100.1 - 0.025 14.2 1.1 0.032 13.9 0.8 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Mto2_bdg PF12808.2 CEP16100.1 - 0.035 14.2 2.5 0.035 14.2 1.7 1.8 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region IncA PF04156.9 CEP16100.1 - 0.039 13.5 1.6 0.051 13.1 1.1 1.2 1 0 0 1 1 1 0 IncA protein Phage_lysis PF03245.8 CEP16100.1 - 0.06 13.3 3.3 0.1 12.6 2.3 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein GAS PF13851.1 CEP16100.1 - 0.065 12.4 4.4 0.09 11.9 3.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CEP16100.1 - 0.07 12.1 2.1 0.092 11.7 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF904 PF06005.7 CEP16100.1 - 0.11 12.7 3.0 0.18 12.1 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 CEP16100.1 - 0.14 9.9 0.8 0.15 9.8 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tho2 PF11262.3 CEP16100.1 - 0.19 10.7 2.1 0.24 10.4 1.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HALZ PF02183.13 CEP16100.1 - 0.23 11.2 2.0 0.48 10.1 1.3 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF2937 PF11157.3 CEP16100.1 - 0.23 10.7 2.3 0.32 10.2 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF972 PF06156.8 CEP16100.1 - 0.62 10.4 3.8 0.95 9.8 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) SlyX PF04102.7 CEP16100.1 - 1.9 8.9 5.5 2.2 8.7 2.3 2.0 1 1 1 2 2 2 0 SlyX HIT PF01230.18 CEP16102.1 - 8.9e-23 80.6 0.6 2.7e-22 79.1 0.1 2.1 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CEP16102.1 - 3.3e-09 36.9 0.0 6.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CEP16102.1 - 2.8e-05 23.7 0.0 5.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 AMP-binding PF00501.23 CEP16104.1 - 2.7e-82 276.3 0.0 5.1e-82 275.4 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP16104.1 - 1e-11 45.6 0.4 2.5e-11 44.3 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 CEP16105.1 - 6.3e-51 173.1 47.9 1.3e-50 172.0 32.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP16105.1 - 2.2e-14 52.8 11.6 2.2e-14 52.8 8.1 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 CEP16105.1 - 8.4e-13 47.3 25.2 8.4e-13 47.3 17.5 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ras PF00071.17 CEP16107.1 - 4.2e-56 188.7 0.0 4.9e-56 188.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP16107.1 - 1e-14 55.0 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP16107.1 - 1.6e-08 34.0 0.0 2.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP16107.1 - 0.0011 18.3 0.0 0.005 16.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CEP16107.1 - 0.0012 18.0 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEP16107.1 - 0.027 13.6 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Hormone_2 PF00123.15 CEP16110.1 - 0.057 13.2 1.9 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Peptide hormone Pkinase PF00069.20 CEP16111.1 - 4.7e-66 222.5 0.0 7.9e-66 221.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16111.1 - 3.5e-34 118.0 0.0 6.4e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CEP16111.1 - 1.8e-18 66.0 24.4 2.3e-10 40.0 6.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CEP16111.1 - 2.7e-09 37.4 0.2 2.7e-09 37.4 0.1 2.9 2 1 0 2 2 2 1 Protein kinase C terminal domain HR1 PF02185.11 CEP16111.1 - 2.7e-06 27.0 22.3 0.00026 20.6 3.5 3.2 3 0 0 3 3 3 2 Hr1 repeat C2 PF00168.25 CEP16111.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 C2 domain PHD_2 PF13831.1 CEP16111.1 - 0.36 10.1 12.3 0.78 9.1 1.7 2.6 2 0 0 2 2 2 0 PHD-finger DUF4062 PF13271.1 CEP16115.1 - 0.011 15.7 0.9 0.94 9.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) Retrotrans_gag PF03732.12 CEP16115.1 - 0.057 13.5 2.6 0.095 12.7 0.1 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein HHH_4 PF14490.1 CEP16119.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain SPA PF08616.5 CEP16120.1 - 3.2e-11 42.9 0.1 6.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CEP16120.1 - 1.4e-05 23.8 0.0 3.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Transport protein Avl9 DENN PF02141.16 CEP16120.1 - 0.011 15.4 0.2 0.83 9.3 0.0 2.4 1 1 1 2 2 2 0 DENN (AEX-3) domain TALPID3 PF15324.1 CEP16121.1 - 0.051 10.9 0.1 0.051 10.9 0.1 2.8 3 0 0 3 3 3 0 Hedgehog signalling target FAM72 PF14976.1 CEP16122.1 - 4.6e-49 166.1 6.3 6.6e-49 165.6 4.4 1.2 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 CEP16122.1 - 0.19 11.8 12.4 0.046 13.7 5.9 2.0 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Fer4_7 PF12838.2 CEP16122.1 - 8 6.9 11.6 5.5 7.4 0.5 2.8 1 1 2 3 3 3 0 4Fe-4S dicluster domain zf-DHHC PF01529.15 CEP16123.1 - 6.2e-05 22.4 0.2 0.00011 21.6 0.2 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase HTH_Tnp_Tc3_2 PF01498.13 CEP16123.1 - 0.025 14.6 0.7 0.06 13.4 0.5 1.6 1 0 0 1 1 1 0 Transposase Tic20 PF09685.5 CEP16123.1 - 0.14 12.1 1.4 0.32 11.0 1.0 1.5 1 1 0 1 1 1 0 Tic20-like protein COG5 PF10392.4 CEP16124.1 - 2.9e-27 95.2 5.7 2.9e-27 95.2 4.0 3.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.6 CEP16124.1 - 1e-05 25.2 1.1 1e-05 25.2 0.8 3.2 4 0 0 4 4 4 1 Vps51/Vps67 Cep57_MT_bd PF06657.8 CEP16124.1 - 0.022 14.7 3.5 0.76 9.7 0.1 3.8 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.5 CEP16124.1 - 3.7 7.6 16.7 0.29 11.2 1.2 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.17 CEP16125.1 - 7.6e-72 236.9 0.5 1.1e-19 69.8 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16125.1 - 1.5e-51 172.2 0.2 3.2e-13 49.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16125.1 - 5.1e-29 99.8 0.2 7.1e-09 35.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CEP16125.1 - 6.2e-16 57.8 2.1 6.2e-16 57.8 1.5 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 CEP16125.1 - 2.2e-13 49.7 3.0 4.6e-05 23.0 0.0 3.7 3 0 0 3 3 3 3 Limkain b1 DSPc PF00782.15 CEP16125.1 - 1e-06 28.3 0.0 2.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP16125.1 - 8.9e-05 21.9 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CEP16125.1 - 0.0035 16.8 0.1 0.0071 15.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) RRM_3 PF08777.6 CEP16125.1 - 0.0037 17.0 0.5 0.21 11.4 0.0 3.5 4 0 0 4 4 4 1 RNA binding motif DUF442 PF04273.8 CEP16125.1 - 0.023 14.5 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Nup35_RRM_2 PF14605.1 CEP16125.1 - 0.096 12.4 0.0 29 4.5 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 CEP16125.1 - 0.22 11.0 0.6 4.7 6.7 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF3608 PF12257.3 CEP16127.1 - 4.3e-75 252.2 0.1 9.8e-75 251.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CEP16127.1 - 4.9e-21 74.2 0.2 2e-19 69.0 0.1 2.7 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DnaJ PF00226.26 CEP16127.1 - 5.7e-16 57.9 0.2 1.7e-15 56.4 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain HLH PF00010.21 CEP16128.1 - 1.6e-13 50.1 2.5 4.6e-13 48.6 1.8 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhoU_div PF01865.11 CEP16128.1 - 0.098 11.8 1.3 0.24 10.5 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function DUF47 Prothymosin PF03247.9 CEP16128.1 - 0.4 10.8 10.4 0.73 10.0 7.2 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Porin_3 PF01459.17 CEP16129.1 - 9.1e-66 221.9 1.3 1.1e-65 221.7 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin tRNA-synt_2 PF00152.15 CEP16130.1 - 1.6e-79 267.1 0.0 2.1e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CEP16130.1 - 2.2e-09 37.0 0.0 4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CEP16130.1 - 0.024 13.8 0.0 1.9 7.5 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Uricase PF01014.13 CEP16131.1 - 4.1e-71 237.4 3.6 9e-36 122.9 0.0 2.0 2 0 0 2 2 2 2 Uricase ArsC PF03960.10 CEP16131.1 - 0.086 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 ArsC family Tox-REase-9 PF15650.1 CEP16131.1 - 0.096 12.8 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 9 Ribosomal_L31 PF01197.13 CEP16131.1 - 0.13 12.3 2.0 2.8 7.9 0.0 3.0 2 1 1 3 3 3 0 Ribosomal protein L31 TruD PF01142.13 CEP16132.1 - 1.2e-67 228.2 0.0 5.4e-67 226.0 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) Med20 PF08612.6 CEP16133.1 - 2.9e-30 105.1 0.1 3.2e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex GPI-anchored PF10342.4 CEP16134.1 - 2.4e-12 47.1 4.7 2.4e-12 47.1 3.3 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CEP16134.1 - 0.1 12.0 2.1 0.1 12.0 0.2 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF4448) Myb_DNA-bind_6 PF13921.1 CEP16135.1 - 0.00016 21.6 0.1 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP16135.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Methyltransf_6 PF03737.10 CEP16136.1 - 8.8e-33 113.3 0.0 1.1e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Fcf2 PF08698.6 CEP16138.1 - 6.2e-34 115.9 3.7 6.2e-34 115.9 2.6 2.7 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing DUF1604 PF07713.8 CEP16138.1 - 0.028 14.1 0.6 0.028 14.1 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1604) AMIN PF11741.3 CEP16138.1 - 0.04 13.8 0.3 0.12 12.3 0.2 1.9 1 0 0 1 1 1 0 AMIN domain Atrophin-1 PF03154.10 CEP16138.1 - 0.059 11.5 15.3 0.072 11.2 10.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF1954 PF09199.5 CEP16138.1 - 0.69 10.1 6.7 2.6 8.3 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1954) Mem_trans PF03547.13 CEP16138.1 - 2.2 6.5 7.7 3 6.0 5.3 1.5 1 0 0 1 1 1 0 Membrane transport protein MFMR PF07777.6 CEP16138.1 - 8.6 6.2 30.3 0.57 10.0 17.1 1.9 2 0 0 2 2 2 0 G-box binding protein MFMR ETF PF01012.16 CEP16139.1 - 1.8e-43 148.0 1.1 2.2e-43 147.7 0.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF498 PF04430.9 CEP16139.1 - 0.089 12.3 0.0 0.87 9.1 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF498/DUF598) HTH_23 PF13384.1 CEP16140.1 - 6.8e-06 25.5 0.0 1.6e-05 24.3 0.0 1.6 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP16140.1 - 0.00064 19.8 0.0 0.00075 19.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP16140.1 - 0.0014 18.5 0.0 0.0066 16.4 0.0 1.9 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.5 CEP16140.1 - 0.0023 17.4 0.0 0.0048 16.4 0.0 1.5 1 1 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.14 CEP16140.1 - 0.0045 16.6 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_7 PF02796.10 CEP16140.1 - 0.006 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_psq PF05225.11 CEP16140.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain LRR_4 PF12799.2 CEP16141.1 - 2e-13 49.6 47.6 0.00073 19.0 0.9 8.7 4 3 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CEP16141.1 - 3.9e-13 47.9 45.7 0.15 12.2 0.0 12.4 13 0 0 13 13 13 5 Leucine Rich repeat LRR_8 PF13855.1 CEP16141.1 - 6.7e-08 32.1 39.4 0.00035 20.2 1.5 6.7 3 2 1 6 6 6 4 Leucine rich repeat UBX PF00789.15 CEP16141.1 - 7.8e-05 22.6 0.1 0.00021 21.2 0.1 1.7 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 CEP16141.1 - 0.0087 15.8 0.2 0.02 14.7 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain LRR_1 PF00560.28 CEP16141.1 - 0.22 11.6 35.1 42 4.7 1.3 11.4 8 3 0 8 8 8 0 Leucine Rich Repeat ApoO PF09769.4 CEP16141.1 - 0.78 9.4 4.4 0.23 11.1 0.2 2.1 2 0 0 2 2 2 0 Apolipoprotein O Acetyltransf_1 PF00583.19 CEP16143.1 - 2.6e-05 24.1 0.0 5.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP16143.1 - 0.036 14.2 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FUSC_2 PF13515.1 CEP16144.1 - 2.4e-20 72.7 9.5 2.4e-20 72.7 6.6 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 CEP16144.1 - 4.7e-12 45.1 3.2 4.7e-12 45.1 2.2 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 CEP16144.1 - 5.2e-11 42.5 0.2 1.2e-10 41.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CEP16144.1 - 9.1e-11 41.2 0.0 9.1e-11 41.2 0.0 3.2 3 1 1 4 4 4 2 Protein of unknown function (DUF2422) ALMT PF11744.3 CEP16144.1 - 4.5e-10 38.7 20.0 7.4e-10 38.0 1.0 3.5 4 0 0 4 4 4 2 Aluminium activated malate transporter SHR3_chaperone PF08229.6 CEP16145.1 - 4.2e-19 68.2 0.6 4.6e-19 68.1 0.4 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Trep_Strep PF09605.5 CEP16145.1 - 0.036 13.7 1.0 0.049 13.2 0.4 1.6 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF872 PF05915.7 CEP16145.1 - 0.11 12.3 0.1 0.42 10.4 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DAGK_prokar PF01219.14 CEP16145.1 - 0.14 11.7 3.5 0.097 12.2 1.2 1.7 2 1 0 2 2 2 0 Prokaryotic diacylglycerol kinase Colicin_V PF02674.11 CEP16145.1 - 0.23 11.3 2.7 0.18 11.6 0.5 1.9 2 1 0 2 2 2 0 Colicin V production protein Aminotran_5 PF00266.14 CEP16146.1 - 1e-24 87.0 0.0 1.2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V FAR1 PF03101.10 CEP16147.1 - 3.1e-05 24.4 1.4 8.7e-05 22.9 1.0 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.12 CEP16147.1 - 0.012 15.1 0.3 0.028 13.9 0.2 1.7 1 0 0 1 1 1 0 SWIM zinc finger Oxysterol_BP PF01237.13 CEP16150.1 - 2e-95 319.3 0.0 2.5e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein MIR PF02815.14 CEP16151.1 - 2.5e-18 66.2 0.1 2.2e-14 53.4 0.1 2.1 1 1 1 2 2 2 2 MIR domain RicinB_lectin_2 PF14200.1 CEP16151.1 - 0.0023 18.2 0.8 0.0069 16.7 0.4 1.9 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Ins145_P3_rec PF08709.6 CEP16151.1 - 0.0032 16.5 0.0 0.0058 15.6 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor gerPA PF10676.4 CEP16151.1 - 0.005 16.6 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Spore germination protein gerPA/gerPF Med26 PF08711.6 CEP16152.1 - 1.1e-13 50.4 0.0 2.4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4355 PF14265.1 CEP16152.1 - 0.0036 17.2 0.9 0.0036 17.2 0.6 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4355) DUF4404 PF14357.1 CEP16152.1 - 2.7 8.4 11.7 0.3 11.5 1.3 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4404) Utp14 PF04615.8 CEP16152.1 - 5 5.1 32.4 3.4 5.7 16.9 2.0 2 0 0 2 2 2 0 Utp14 protein Peptidase_C12 PF01088.16 CEP16152.1 - 7.9 5.5 7.3 0.88 8.7 0.2 2.4 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Ribosomal_60s PF00428.14 CEP16153.1 - 6.3e-25 87.3 12.3 7.3e-25 87.1 8.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Jag_N PF14804.1 CEP16153.1 - 0.033 14.2 0.3 0.072 13.1 0.2 1.6 1 0 0 1 1 1 0 Jag N-terminus DPM2 PF07297.7 CEP16154.1 - 1.6e-23 82.7 1.3 1.9e-23 82.5 0.9 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 CEP16154.1 - 0.028 14.0 1.3 0.03 13.9 0.9 1.1 1 0 0 1 1 1 0 PIG-P Yip1 PF04893.12 CEP16154.1 - 0.26 10.7 4.3 0.31 10.5 3.0 1.1 1 0 0 1 1 1 0 Yip1 domain MFS_1_like PF12832.2 CEP16154.1 - 0.41 10.4 3.5 0.54 10.0 2.4 1.2 1 0 0 1 1 1 0 MFS_1 like family RNA_pol_A_bac PF01000.21 CEP16155.1 - 3.2e-30 104.5 0.0 6.3e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CEP16155.1 - 2.3e-17 61.8 0.0 3e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Adeno_52K PF03052.10 CEP16155.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa DAHP_synth_1 PF00793.15 CEP16156.1 - 1.1e-65 221.0 0.1 1.3e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family NUMOD3 PF07460.6 CEP16156.1 - 0.032 14.1 0.2 0.11 12.3 0.4 1.7 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) Methyltransf_26 PF13659.1 CEP16157.1 - 6e-11 42.4 0.0 8.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP16157.1 - 2.8e-05 23.7 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP16157.1 - 0.00046 19.6 0.0 0.047 13.0 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain PCMT PF01135.14 CEP16157.1 - 0.011 15.2 0.1 0.024 14.1 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 CEP16157.1 - 0.012 15.0 0.3 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase DUF1770 PF08589.5 CEP16158.1 - 0.1 13.2 0.9 0.13 12.8 0.6 1.2 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) PH_4 PF15404.1 CEP16159.1 - 1.8e-20 73.2 6.2 1.1e-18 67.4 2.1 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CEP16159.1 - 3.7e-09 36.7 1.5 0.015 15.5 0.8 4.3 3 2 0 3 3 3 3 PH domain DDE_3 PF13358.1 CEP16160.1 - 6.7e-10 38.8 0.1 5.8e-09 35.8 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP16160.1 - 7.7e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP16160.1 - 0.00011 21.6 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 CEP16160.1 - 0.0017 19.0 0.0 0.0032 18.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CEP16160.1 - 0.0034 16.5 0.0 0.0069 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 CEP16160.1 - 0.0059 16.5 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 CEP16160.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 MarR family SSXT PF05030.7 CEP16160.1 - 0.14 11.7 0.2 0.48 10.0 0.1 1.9 2 0 0 2 2 2 0 SSXT protein (N-terminal region) DUF2680 PF10925.3 CEP16160.1 - 0.17 11.7 2.0 0.4 10.5 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Glutaredoxin PF00462.19 CEP16161.1 - 5.3e-16 58.3 0.0 8.5e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin IGPS PF00218.16 CEP16162.1 - 9e-97 323.0 0.6 2.3e-96 321.7 0.1 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 CEP16162.1 - 2.5e-59 200.1 0.0 1.1e-53 181.7 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 CEP16162.1 - 8.7e-54 181.9 0.0 1.6e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CEP16162.1 - 3.5e-11 42.9 0.0 1.9e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 CEP16162.1 - 0.025 14.1 0.5 0.34 10.4 0.0 2.7 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain Homeobox PF00046.24 CEP16163.1 - 6.6e-16 57.6 7.5 7.1e-16 57.5 2.2 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CEP16163.1 - 9.1e-05 22.0 0.8 0.00024 20.7 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain DUF1151 PF06625.6 CEP16163.1 - 6.8 6.4 13.7 1.1 9.0 0.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1151) DUF3318 PF11780.3 CEP16164.1 - 0.11 12.0 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) eIF3_p135 PF12807.2 CEP16164.1 - 0.33 10.8 3.2 2.3 8.1 0.2 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Fes1 PF08609.5 CEP16165.1 - 0.096 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF2730 PF10805.3 CEP16167.1 - 0.0049 16.5 0.3 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF2572 PF10833.3 CEP16172.1 - 0.0042 16.5 0.2 0.0083 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2572) DUF4163 PF13739.1 CEP16172.1 - 0.071 13.9 3.3 6.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) Exo_endo_phos_2 PF14529.1 CEP16173.1 - 6.6e-10 38.6 0.5 2.1e-09 37.0 0.4 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 CEP16173.1 - 2e-09 37.1 0.0 4.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP16173.1 - 0.00019 21.4 0.3 0.00033 20.6 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family M_domain PF12938.2 CEP16173.1 - 0.06 13.1 0.3 0.094 12.5 0.2 1.2 1 0 0 1 1 1 0 M domain of GW182 PYST-C1 PF09690.5 CEP16175.1 - 0.16 11.5 1.0 0.29 10.7 0.7 1.4 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) MAP65_ASE1 PF03999.7 CEP16175.1 - 7.2 5.0 8.9 12 4.3 6.2 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) OrfB_Zn_ribbon PF07282.6 CEP16176.1 - 0.00021 20.8 0.2 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DUF2183 PF09949.4 CEP16177.1 - 1.5e-25 89.0 0.1 5.9e-25 87.1 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 CEP16177.1 - 0.21 11.1 2.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Acetyltransf_1 PF00583.19 CEP16178.1 - 1.3e-15 57.2 0.1 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP16178.1 - 6e-10 39.1 0.0 8.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP16178.1 - 7.4e-08 32.5 0.0 9.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP16178.1 - 8.3e-07 28.6 0.1 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CEP16178.1 - 7.8e-05 22.5 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP16178.1 - 0.00098 19.3 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP16178.1 - 0.0023 17.7 0.1 0.0042 16.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEP16178.1 - 0.004 17.1 0.2 0.0048 16.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SAE2 PF08573.5 CEP16179.1 - 6.4e-07 29.9 3.7 6.4e-07 29.9 2.6 4.1 2 2 1 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HrpB7 PF09486.5 CEP16179.1 - 0.011 15.7 6.6 0.016 15.1 4.0 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Occludin_ELL PF07303.8 CEP16179.1 - 0.19 12.4 7.5 0.13 12.9 1.7 2.6 2 0 0 2 2 2 0 Occludin homology domain DUF4140 PF13600.1 CEP16179.1 - 3.6 8.0 8.5 3 8.3 0.6 3.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF883 PF05957.8 CEP16179.1 - 3.9 7.9 9.5 6.8 7.1 0.6 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) RhoGAP PF00620.22 CEP16180.1 - 1.8e-23 82.8 0.6 4.6e-23 81.5 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain MAP65_ASE1 PF03999.7 CEP16181.1 - 6.3e-61 206.7 34.1 9.3e-61 206.1 23.6 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) SPT6_acidic PF14632.1 CEP16181.1 - 0.061 13.4 9.0 0.08 13.1 4.6 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DUF4611 PF15387.1 CEP16181.1 - 0.13 12.4 5.8 0.15 12.2 0.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cyt-b5 PF00173.23 CEP16182.1 - 7.3e-23 80.1 0.3 9.1e-23 79.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RL11D PF11088.3 CEP16184.1 - 0.066 13.0 0.2 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 DDA1 PF10172.4 CEP16185.1 - 0.019 14.7 0.8 0.019 14.7 0.5 2.4 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase DUF605 PF04652.11 CEP16185.1 - 3.4 6.9 20.8 0.63 9.3 9.5 2.1 2 0 0 2 2 2 0 Vta1 like HLH PF00010.21 CEP16186.1 - 1.4e-12 47.1 3.0 3.1e-12 45.9 0.6 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nucleo_P87 PF07267.6 CEP16186.1 - 1.7 7.2 9.9 0.62 8.6 4.8 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 bZIP_1 PF00170.16 CEP16186.1 - 9.9 6.2 11.2 29 4.6 3.3 2.8 2 1 0 2 2 2 0 bZIP transcription factor CNH PF00780.17 CEP16187.1 - 1.1e-38 133.2 0.0 1.8e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 CEP16187.1 - 1.4e-36 124.9 0.6 9.6e-35 119.0 0.1 3.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CEP16187.1 - 1.8e-13 50.4 14.1 2.6e-10 40.2 0.2 5.4 4 2 2 7 7 7 2 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 CEP16187.1 - 1.3e-11 44.3 3.3 1.3e-11 44.3 2.3 3.5 4 0 0 4 4 4 1 Region in Clathrin and VPS HemX PF04375.9 CEP16187.1 - 0.012 14.2 0.1 0.012 14.2 0.1 1.7 2 0 0 2 2 2 0 HemX TPR_14 PF13428.1 CEP16187.1 - 0.021 15.4 2.0 21 6.1 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CEP16187.1 - 0.023 14.8 2.6 0.69 10.0 0.1 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CEP16187.1 - 0.041 13.5 3.7 1.7 8.3 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP16187.1 - 0.47 10.4 6.4 5.4 7.1 0.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Dynein_light PF01221.13 CEP16188.1 - 0.018 15.0 0.3 0.027 14.4 0.2 1.4 1 0 0 1 1 1 0 Dynein light chain type 1 Glyco_transf_20 PF00982.16 CEP16191.1 - 4e-156 520.2 0.0 5.4e-156 519.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEP16191.1 - 3.3e-77 258.5 0.0 5.5e-77 257.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CEP16191.1 - 1e-06 28.5 0.0 0.0018 17.8 0.0 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase DUF2929 PF11151.3 CEP16193.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) TATR PF03430.8 CEP16194.1 - 0.0075 14.9 0.7 0.01 14.5 0.5 1.2 1 0 0 1 1 1 1 Trans-activating transcriptional regulator Ndr PF03096.9 CEP16194.1 - 0.095 11.1 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Ndr family Aminotran_3 PF00202.16 CEP16195.1 - 2.2e-93 312.8 0.0 2.6e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CEP16195.1 - 0.00014 20.9 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PMT PF02366.13 CEP16196.1 - 7.2e-75 251.5 13.5 1.4e-74 250.5 9.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEP16196.1 - 8.5e-30 103.6 0.2 1.7e-29 102.7 0.2 1.5 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 CEP16197.1 - 1.8e-30 105.4 0.0 2.3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP16197.1 - 2.3e-10 41.0 0.0 3.9e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 Miro-like protein Glyco_transf_22 PF03901.12 CEP16198.1 - 2.6e-82 277.0 22.3 3.3e-82 276.7 15.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4366 PF14283.1 CEP16199.1 - 0.042 13.2 0.3 0.085 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) zf-RING_2 PF13639.1 CEP16200.1 - 2.4e-14 52.8 4.9 3.5e-14 52.3 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP16200.1 - 8.7e-10 38.5 1.8 1.3e-09 38.0 1.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP16200.1 - 9.2e-09 34.8 4.3 1.4e-08 34.2 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP16200.1 - 2.4e-07 30.3 2.0 3.4e-07 29.8 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP16200.1 - 5.6e-07 29.4 4.9 8.4e-07 28.9 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP16200.1 - 3.5e-06 26.6 4.0 5.1e-06 26.1 2.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CEP16200.1 - 9e-05 22.2 4.5 0.00017 21.3 2.5 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CEP16200.1 - 0.0022 17.5 4.3 0.0034 16.9 3.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4079 PF13301.1 CEP16200.1 - 0.0041 17.1 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) FANCL_C PF11793.3 CEP16200.1 - 0.027 14.4 5.8 0.34 10.9 4.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CEP16200.1 - 0.046 13.7 3.9 0.12 12.4 2.6 1.7 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.24 CEP16200.1 - 0.065 12.9 4.4 0.11 12.2 3.1 1.4 1 0 0 1 1 1 0 PHD-finger Endonuclease_7 PF02945.10 CEP16200.1 - 0.081 12.6 3.3 1.4 8.6 0.1 2.3 1 1 1 2 2 2 0 Recombination endonuclease VII zf-RING-like PF08746.6 CEP16200.1 - 0.31 11.0 3.6 0.55 10.2 2.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-FCS PF06467.9 CEP16200.1 - 1.5 8.5 4.9 0.5 10.0 0.3 2.2 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Pkinase PF00069.20 CEP16201.1 - 3e-40 138.0 0.0 6.5e-39 133.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16201.1 - 2.5e-15 56.2 0.0 1.1e-11 44.2 0.0 3.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP16201.1 - 0.029 13.3 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like BTB PF00651.26 CEP16202.1 - 1.1e-15 57.5 1.7 4.1e-11 42.8 0.3 2.8 2 0 0 2 2 2 2 BTB/POZ domain CAP_GLY PF01302.20 CEP16202.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 CAP-Gly domain PPTA PF01239.17 CEP16202.1 - 0.026 13.8 1.1 0.17 11.2 0.1 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat ABC2_membrane_3 PF12698.2 CEP16202.1 - 3.6 6.5 9.1 7.7 5.4 6.3 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein TSA PF03249.8 CEP16202.1 - 4.6 5.6 9.3 7.6 4.9 6.5 1.2 1 0 0 1 1 1 0 Type specific antigen PI3K_1B_p101 PF10486.4 CEP16203.1 - 0.11 10.0 0.1 0.11 10.0 0.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UCH_1 PF13423.1 CEP16204.1 - 4.5e-61 206.8 1.2 7e-61 206.2 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CEP16204.1 - 5.8e-25 88.4 0.0 1.5e-24 87.1 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 CEP16204.1 - 5.1e-15 55.3 0.5 2.2e-14 53.2 0.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Acyltransferase PF01553.16 CEP16205.1 - 3.1e-05 23.4 0.0 5.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Y_phosphatase2 PF03162.8 CEP16206.1 - 1.4e-30 105.8 0.3 3e-30 104.7 0.0 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CEP16206.1 - 0.01 16.0 0.1 0.044 14.0 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Rib_recp_KP_reg PF05104.7 CEP16206.1 - 0.022 15.2 1.7 0.034 14.6 1.2 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Y_phosphatase PF00102.22 CEP16206.1 - 0.032 13.5 1.6 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF1675 PF07897.6 CEP16206.1 - 0.081 12.7 4.2 0.11 12.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Prothymosin PF03247.9 CEP16206.1 - 1.1 9.4 15.3 2.4 8.3 10.6 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family CDC73 PF05179.9 CEP16207.1 - 5.5e-56 189.9 10.0 1.2e-55 188.8 6.9 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Pro-NT_NN PF07421.6 CEP16207.1 - 0.051 13.0 0.0 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor DDE_3 PF13358.1 CEP16209.1 - 1.5e-28 99.3 0.0 4.5e-28 97.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 CEP16209.1 - 7e-05 22.9 0.1 0.00036 20.6 0.0 2.1 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_ISAZ013 PF07592.6 CEP16209.1 - 0.047 12.4 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Ras PF00071.17 CEP16212.1 - 0.00073 18.9 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Ras family ECH PF00378.15 CEP16215.1 - 1.2e-38 132.6 0.0 1.5e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family UQ_con PF00179.21 CEP16216.1 - 5.8e-44 148.9 0.0 1.2e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CEP16216.1 - 0.026 14.3 0.2 0.026 14.3 0.1 2.5 2 1 0 2 2 2 0 RWD domain MFS_1 PF07690.11 CEP16217.1 - 4.4e-34 117.7 63.3 4.2e-25 88.2 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP16217.1 - 7e-05 21.4 36.9 0.00052 18.5 10.9 2.6 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 CEP16217.1 - 0.00021 20.0 16.9 0.00021 20.0 11.7 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Arm PF00514.18 CEP16218.1 - 3.5e-37 124.9 24.6 3.1e-08 33.1 0.2 11.4 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEP16218.1 - 3.4e-22 78.5 12.9 5.6e-05 23.3 0.0 8.0 4 4 3 7 7 7 7 HEAT repeats HEAT PF02985.17 CEP16218.1 - 7.1e-22 75.4 20.8 0.0065 16.4 0.0 10.2 11 0 0 11 11 11 5 HEAT repeat Vac14_Fab1_bd PF12755.2 CEP16218.1 - 4.6e-07 30.1 2.1 0.25 11.7 0.1 4.8 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CEP16218.1 - 1.5e-05 25.2 27.3 0.3 11.6 0.2 8.5 7 5 3 10 10 10 4 HEAT-like repeat Cnd1 PF12717.2 CEP16218.1 - 0.00015 21.6 7.3 0.0005 19.9 0.0 4.8 5 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.4 CEP16218.1 - 0.0052 16.5 1.5 12 5.6 0.0 4.8 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.3 CEP16218.1 - 0.052 13.2 3.2 8 6.1 0.0 4.7 3 2 2 5 5 5 0 Domain of unknown function (DUF3361) ATP-synt_C PF00137.16 CEP16219.1 - 9.1e-28 95.9 28.7 4e-16 58.6 7.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C MBOAT PF03062.14 CEP16220.1 - 1.8e-35 122.6 13.8 1.8e-35 122.6 9.5 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family NAP PF00956.13 CEP16221.1 - 3.8e-85 284.9 6.7 3.8e-85 284.9 4.6 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) APG6 PF04111.7 CEP16224.1 - 0.036 13.1 32.9 0.024 13.6 9.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Sulfatase PF00884.18 CEP16224.1 - 0.13 11.3 1.7 0.13 11.4 0.2 1.6 2 0 0 2 2 2 0 Sulfatase FlaC_arch PF05377.6 CEP16224.1 - 0.14 12.0 12.2 0.19 11.6 0.7 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 CEP16224.1 - 0.23 11.8 24.0 0.9 9.9 2.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Mod_r PF07200.8 CEP16224.1 - 0.49 10.3 28.5 1.3 8.9 8.9 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Gp-FAR-1 PF05823.7 CEP16224.1 - 1 9.2 8.8 0.28 11.1 2.7 2.1 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) bZIP_1 PF00170.16 CEP16224.1 - 2.4 8.2 20.1 2.6 8.0 2.0 4.2 3 1 0 3 3 3 0 bZIP transcription factor Lebercilin PF15619.1 CEP16224.1 - 2.7 7.3 30.4 0.32 10.4 14.1 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.3 CEP16224.1 - 2.7 7.1 30.7 0.64 9.2 8.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) ERM PF00769.14 CEP16224.1 - 3.1 7.2 31.1 8.8 5.7 21.7 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family IncA PF04156.9 CEP16224.1 - 8.1 5.9 40.4 4.3e+03 -2.9 28.0 2.2 1 1 0 1 1 1 0 IncA protein Syntaxin-6_N PF09177.6 CEP16224.1 - 9.6 6.6 23.5 1.2 9.5 3.9 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal rve PF00665.21 CEP16225.1 - 2.4e-22 79.2 0.0 4.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP16225.1 - 0.0053 16.2 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CEP16225.1 - 0.022 14.6 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 DDE domain KH_5 PF13184.1 CEP16225.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 NusA-like KH domain DDE_3 PF13358.1 CEP16228.1 - 1.1e-11 44.7 0.0 1.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP16228.1 - 9e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Transposase Tannase PF07519.6 CEP16231.1 - 0.069 11.8 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Asp_protease_2 PF13650.1 CEP16232.1 - 1.5e-06 28.6 0.0 3.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CEP16232.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP16232.1 - 0.00016 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 CEP16232.1 - 0.00032 20.1 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CEP16232.1 - 0.0079 16.0 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease OCIA PF07051.6 CEP16232.1 - 0.015 14.6 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) Asp_protease PF09668.5 CEP16232.1 - 0.02 14.4 0.1 0.059 12.9 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.18 CEP16232.1 - 0.042 13.7 0.5 0.094 12.6 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 CEP16233.1 - 2.3e-06 27.5 0.0 1.7e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2560 PF10834.3 CEP16233.1 - 0.029 14.3 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) RP-C_C PF11800.3 CEP16233.1 - 1.8 8.1 7.4 2.6 7.6 1.2 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region AAA_30 PF13604.1 CEP16234.1 - 1.4e-10 41.0 0.0 1.8e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 CEP16234.1 - 2.2e-10 40.0 0.0 2.5e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_22 PF13401.1 CEP16234.1 - 7.7e-06 26.0 0.1 2.4e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CEP16234.1 - 0.00015 21.3 0.0 0.00031 20.3 0.0 1.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CEP16234.1 - 0.00019 21.0 0.1 0.0003 20.3 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain MobB PF03205.9 CEP16234.1 - 0.0019 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Helicase_RecD PF05127.9 CEP16234.1 - 0.0021 17.7 0.0 0.05 13.2 0.0 2.0 1 1 0 1 1 1 1 Helicase ArgK PF03308.11 CEP16234.1 - 0.007 15.1 0.0 0.0079 15.0 0.0 1.1 1 0 0 1 1 1 1 ArgK protein AAA_14 PF13173.1 CEP16234.1 - 0.017 14.9 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain TK PF00265.13 CEP16234.1 - 0.037 13.5 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase GBP PF02263.14 CEP16234.1 - 0.049 12.6 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DUF258 PF03193.11 CEP16234.1 - 0.054 12.6 0.1 0.13 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 CEP16234.1 - 0.056 13.7 0.2 0.1 12.8 0.0 1.5 2 0 0 2 2 2 0 ABC transporter DUF87 PF01935.12 CEP16234.1 - 0.058 13.2 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 CEP16234.1 - 0.072 13.2 0.0 0.088 12.9 0.0 1.4 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 CEP16234.1 - 0.094 12.3 0.1 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 CEP16234.1 - 0.099 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 CEP16234.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CEP16234.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 CEP16234.1 - 0.11 11.1 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 CEP16234.1 - 0.11 11.9 0.6 0.21 11.0 0.4 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 CEP16234.1 - 0.12 11.2 0.1 0.61 8.9 0.0 1.7 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF2791 PF10923.3 CEP16234.1 - 0.15 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_19 PF13245.1 CEP16234.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain DUF4609 PF15382.1 CEP16235.1 - 0.11 12.1 2.4 0.11 12.2 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4609) DUF3324 PF11797.3 CEP16235.1 - 0.15 11.8 1.6 0.17 11.5 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) Macoilin PF09726.4 CEP16235.1 - 0.86 7.8 4.9 0.95 7.6 3.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3324 PF11797.3 CEP16236.1 - 0.074 12.7 3.2 0.11 12.1 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) TFIIF_alpha PF05793.7 CEP16236.1 - 0.36 9.1 10.6 0.41 8.9 7.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3439 PF11921.3 CEP16236.1 - 1.1 9.0 4.4 1.3 8.8 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Macoilin PF09726.4 CEP16236.1 - 1.2 7.3 5.6 1.3 7.1 3.9 1.0 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 CEP16236.1 - 1.7 8.0 9.4 1.9 7.9 6.5 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cut8_N PF14482.1 CEP16236.1 - 2.8 7.9 5.6 4.9 7.2 3.9 1.4 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Herpes_DNAp_acc PF04929.7 CEP16236.1 - 9.7 5.0 8.9 11 4.8 6.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Helitron_like_N PF14214.1 CEP16237.1 - 1.8e-21 76.7 0.0 3.8e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus UvrD_C_2 PF13538.1 CEP16237.1 - 1.9e-10 40.7 0.0 8.5e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEP16237.1 - 4.9e-05 21.2 0.0 7.6e-05 20.6 0.0 1.2 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 CEP16237.1 - 0.00049 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase GDH_N PF12466.3 CEP16237.1 - 0.05 13.6 0.4 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal PIF1 PF05970.9 CEP16237.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase zf-CCHC_2 PF13696.1 CEP16238.1 - 0.046 13.2 0.6 0.08 12.4 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Transposase_21 PF02992.9 CEP16238.1 - 0.075 12.1 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 Cwf_Cwc_15 PF04889.7 CEP16239.1 - 0.07 12.8 0.2 0.09 12.4 0.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DCP2 PF05026.8 CEP16239.1 - 0.15 12.0 0.6 2.6 8.0 0.1 2.3 1 1 1 2 2 2 0 Dcp2, box A domain HTH_Tnp_Tc5 PF03221.11 CEP16244.1 - 8.1e-11 41.5 0.0 2.6e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 CEP16244.1 - 0.00056 19.1 0.1 0.0035 16.5 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF2489 PF10675.4 CEP16245.1 - 0.17 11.5 5.2 0.36 10.5 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) Phage_int_SAM_4 PF13495.1 CEP16246.1 - 0.0092 16.2 0.5 0.0092 16.2 0.3 2.0 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain RVT_1 PF00078.22 CEP16247.1 - 1.9e-15 56.8 0.1 3.8e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CEP16247.1 - 3e-05 24.3 0.1 6.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 RNase H Phage_integrase PF00589.17 CEP16247.1 - 0.00083 19.0 0.0 0.0041 16.8 0.0 2.2 3 0 0 3 3 3 1 Phage integrase family DNA_pol_viral_C PF00336.13 CEP16247.1 - 0.001 18.3 0.1 0.0023 17.2 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain TPT PF03151.11 CEP16248.1 - 3.1e-18 65.8 35.0 3.4e-18 65.7 8.4 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CEP16248.1 - 7.6e-12 44.7 27.2 1.5e-11 43.8 18.9 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP16248.1 - 9.6e-07 28.8 34.2 0.00018 21.5 9.6 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CEP16248.1 - 0.00036 19.7 18.7 0.18 10.9 11.7 3.0 2 1 0 2 2 2 1 Nucleotide-sugar transporter DUF2648 PF10855.3 CEP16248.1 - 0.0026 17.1 0.0 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2648) Topoisom_bac PF01131.15 CEP16249.1 - 3.7e-94 315.8 0.0 4.4e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 CEP16249.1 - 5.8e-25 86.9 15.8 2.5e-12 46.4 1.0 2.9 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.17 CEP16249.1 - 2.8e-18 65.7 0.0 5.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Evr1_Alr PF04777.8 CEP16250.1 - 4e-23 81.1 0.1 6.3e-23 80.4 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family zf-CCCH PF00642.19 CEP16251.1 - 3.9e-08 32.7 41.1 2.7e-05 23.7 0.8 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CEP16251.1 - 0.0096 15.8 5.8 0.0096 15.8 4.0 5.9 6 1 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type RVT_1 PF00078.22 CEP16252.1 - 8.1e-08 31.8 0.0 4.6e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) S10_plectin PF03501.10 CEP16253.1 - 1e-41 140.6 0.0 1.2e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Kinase-like PF14531.1 CEP16253.1 - 0.0042 16.0 0.0 0.0055 15.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF2250 PF10007.4 CEP16253.1 - 0.071 13.0 0.6 14 5.6 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_45 PF14947.1 CEP16253.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DUF2962 PF11176.3 CEP16255.1 - 0.11 12.0 4.1 0.18 11.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) DUF4407 PF14362.1 CEP16255.1 - 0.17 10.7 4.5 0.29 10.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AMP-binding PF00501.23 CEP16256.1 - 9.2e-78 261.4 0.0 4.3e-77 259.2 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP16256.1 - 2.6e-11 44.2 0.0 2.2e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Phtf-FEM1B_bdg PF12129.3 CEP16256.1 - 0.11 11.8 0.4 0.21 10.9 0.3 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor MFS_1 PF07690.11 CEP16257.1 - 1.2e-52 178.7 50.8 1.2e-52 178.7 35.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CEP16257.1 - 7.9e-18 63.9 17.5 7.9e-18 63.9 12.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CEP16257.1 - 1.2e-13 50.4 14.9 1.2e-13 50.4 10.3 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter AAA_3 PF07726.6 CEP16257.1 - 0.037 13.6 0.1 0.37 10.4 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.21 CEP16258.1 - 4.8e-07 29.7 28.0 0.00023 21.3 3.7 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP16258.1 - 0.00034 20.7 10.9 0.0025 18.0 4.3 3.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP16258.1 - 0.011 15.9 4.1 0.011 15.9 2.8 4.3 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP16258.1 - 0.035 14.2 1.4 0.035 14.2 1.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP16258.1 - 0.36 11.1 7.3 2.4 8.4 1.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IncA PF04156.9 CEP16259.1 - 7.9 6.0 16.3 1 8.9 1.5 2.8 3 0 0 3 3 3 0 IncA protein Atg14 PF10186.4 CEP16260.1 - 0.00073 18.5 0.7 0.00073 18.5 0.5 1.8 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 CEP16260.1 - 0.0021 17.7 0.7 0.0063 16.2 0.5 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper GAS PF13851.1 CEP16260.1 - 0.0035 16.5 1.5 0.0035 16.5 1.0 2.0 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CEP16260.1 - 0.0037 17.0 3.2 0.0037 17.0 2.2 2.1 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 CEP16260.1 - 0.0039 17.0 3.7 0.0039 17.0 2.6 2.9 3 1 0 3 3 3 1 Autophagy protein 16 (ATG16) DUF3972 PF13118.1 CEP16260.1 - 0.0043 17.1 2.4 0.0043 17.1 1.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3972) THOC7 PF05615.8 CEP16260.1 - 0.0095 16.2 1.8 0.0095 16.2 1.2 2.2 2 0 0 2 2 2 1 Tho complex subunit 7 Rootletin PF15035.1 CEP16260.1 - 0.019 14.9 4.1 0.028 14.4 0.6 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Syntaxin-6_N PF09177.6 CEP16260.1 - 0.027 14.8 1.0 0.027 14.8 0.7 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF848 PF05852.6 CEP16260.1 - 0.062 13.1 3.8 0.16 11.7 2.7 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) WEMBL PF05701.6 CEP16260.1 - 0.076 11.4 5.7 0.036 12.5 2.4 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DivIVA PF05103.8 CEP16260.1 - 0.084 12.9 8.1 0.53 10.3 5.6 2.4 1 1 0 1 1 1 0 DivIVA protein MtrB PF05440.7 CEP16260.1 - 0.092 12.7 0.1 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF948 PF06103.6 CEP16260.1 - 0.26 11.1 2.9 0.38 10.6 0.2 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 CEP16260.1 - 0.29 10.6 9.2 0.059 12.9 1.3 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 CEP16260.1 - 0.3 10.5 3.8 1.1 8.7 2.5 2.2 1 1 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 CEP16260.1 - 0.35 11.2 7.6 0.19 12.0 1.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 CEP16260.1 - 0.39 9.7 6.8 0.043 12.8 1.4 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 CEP16260.1 - 0.44 10.4 8.0 0.045 13.6 1.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CEP16260.1 - 0.73 9.4 5.6 2.4 7.7 3.9 2.0 1 1 0 1 1 1 0 IncA protein DUF904 PF06005.7 CEP16260.1 - 6.3 7.1 9.2 0.12 12.7 1.1 2.1 3 0 0 3 3 1 0 Protein of unknown function (DUF904) ubiquitin PF00240.18 CEP16261.1 - 0.0047 16.3 0.1 0.019 14.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin family DNA_pol_viral_N PF00242.12 CEP16261.1 - 0.061 12.3 11.9 0.069 12.1 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CPDase PF07823.6 CEP16261.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein DUF605 PF04652.11 CEP16261.1 - 0.31 10.3 7.4 0.34 10.2 5.1 1.1 1 0 0 1 1 1 0 Vta1 like Ndc1_Nup PF09531.5 CEP16261.1 - 4.2 5.6 9.9 4.6 5.5 6.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pol_alpha_B_N PF08418.5 CEP16261.1 - 5.1 6.5 13.1 7 6.1 9.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PRP38_assoc PF12871.2 CEP16261.1 - 5.2 7.6 60.5 8.1 7.0 41.7 1.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF566 PF04484.7 CEP16261.1 - 5.5 6.4 22.2 6.9 6.0 15.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-C2H2 PF00096.21 CEP16263.1 - 6.1e-06 26.2 6.7 0.0067 16.7 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP16263.1 - 9.9e-05 22.4 4.4 0.072 13.4 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP16263.1 - 0.00041 20.4 10.4 0.0078 16.3 0.9 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CEP16263.1 - 0.014 15.4 4.2 0.034 14.2 3.0 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CEP16263.1 - 0.02 15.1 2.4 0.31 11.3 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CEP16263.1 - 0.4 10.8 5.2 0.7 10.0 0.2 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NUDIX PF00293.23 CEP16265.1 - 6.4e-16 58.2 0.2 7.7e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NOGCT PF08155.6 CEP16266.1 - 1.3e-29 101.6 2.1 3.6e-29 100.2 1.4 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 CEP16266.1 - 3.2e-29 100.5 0.3 6.9e-29 99.5 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CEP16266.1 - 3.9e-19 68.7 0.0 1e-18 67.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP16266.1 - 8.4e-10 38.1 0.0 1.9e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CEP16266.1 - 6.8e-07 29.7 0.1 5.2e-06 26.9 0.0 2.5 3 0 0 3 3 2 1 Miro-like protein AIG1 PF04548.11 CEP16266.1 - 0.00062 18.9 0.0 0.0014 17.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CEP16266.1 - 0.0039 17.0 0.1 1.3 8.7 0.0 3.4 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 CEP16266.1 - 0.0044 16.4 0.3 0.15 11.4 0.2 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CEP16266.1 - 0.0071 15.0 0.9 0.041 12.5 0.1 2.5 1 1 1 3 3 3 1 G-protein alpha subunit DUF258 PF03193.11 CEP16266.1 - 0.0078 15.4 0.0 0.058 12.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP16266.1 - 0.018 15.2 0.1 0.16 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 CEP16266.1 - 0.058 13.0 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Herpes_UL17 PF04559.7 CEP16266.1 - 2.9 6.3 5.5 4.5 5.7 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein RhoGAP PF00620.22 CEP16267.1 - 2e-30 105.3 0.0 1.2e-29 102.9 0.0 2.2 1 1 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CEP16267.1 - 1.2e-22 79.6 55.1 8.8e-11 41.7 5.3 5.0 5 0 0 5 5 5 4 LIM domain zf-RVT PF13966.1 CEP16268.1 - 0.00047 20.4 0.8 0.00047 20.4 0.5 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase FAT PF02259.18 CEP16269.1 - 6.2e-122 406.9 3.4 6.6e-122 406.8 0.2 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 CEP16269.1 - 6.2e-61 205.8 0.7 1.1e-60 205.0 0.5 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CEP16269.1 - 2.5e-59 199.8 3.0 3.6e-57 192.7 0.1 4.3 4 0 0 4 4 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CEP16269.1 - 1.1e-42 144.1 1.7 1.1e-42 144.1 1.2 2.7 2 0 0 2 2 2 1 Rapamycin binding domain FATC PF02260.15 CEP16269.1 - 6.6e-17 60.6 0.6 1.8e-16 59.2 0.4 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 CEP16269.1 - 2.7e-14 53.2 9.2 0.034 14.4 0.0 9.7 6 3 4 10 10 10 3 HEAT repeats HEAT_EZ PF13513.1 CEP16269.1 - 4.6e-13 49.2 23.0 2.4e-06 27.8 0.1 10.3 8 2 3 11 11 10 4 HEAT-like repeat HEAT PF02985.17 CEP16269.1 - 5.4e-12 44.7 18.2 0.0061 16.5 0.0 9.8 10 0 0 10 10 9 3 HEAT repeat TPR_16 PF13432.1 CEP16269.1 - 2.5e-09 37.5 5.0 0.012 16.2 0.9 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.2 CEP16269.1 - 2.2e-05 24.7 7.0 18 5.7 0.0 7.7 6 3 2 8 8 8 0 Vacuolar 14 Fab1-binding region TPR_19 PF14559.1 CEP16269.1 - 5.2e-05 23.5 2.9 0.14 12.4 0.4 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat MMS19_C PF12460.3 CEP16269.1 - 0.00016 20.5 0.5 0.025 13.3 0.0 3.4 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Apc3 PF12895.2 CEP16269.1 - 0.00035 20.6 0.4 0.48 10.5 0.0 4.4 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2454 PF10521.4 CEP16269.1 - 0.0042 16.1 2.5 0.2 10.6 0.0 4.0 4 1 1 5 5 5 1 Protein of unknown function (DUF2454) TPR_12 PF13424.1 CEP16269.1 - 0.013 15.4 4.9 3.4 7.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP16269.1 - 0.031 14.1 6.0 11 6.2 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.17 CEP16271.1 - 7.4e-42 142.4 0.1 1.2e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP16271.1 - 3.1e-10 40.5 0.1 7.3e-10 39.3 0.0 1.6 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP16271.1 - 1e-08 34.6 0.3 1.4e-08 34.2 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP16271.1 - 6.3e-05 22.4 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CEP16271.1 - 0.067 12.4 0.1 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CEP16271.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S2 PF00318.15 CEP16272.1 - 7.4e-41 139.6 0.1 1.3e-19 70.3 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_L27e PF01777.13 CEP16273.1 - 2.2e-37 127.0 6.1 3.3e-37 126.4 4.2 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CEP16273.1 - 0.00054 19.5 6.3 0.0014 18.2 4.2 2.1 1 1 0 1 1 1 1 KOW motif PP1_bind PF15276.1 CEP16274.1 - 0.029 14.3 0.6 0.24 11.4 0.3 2.6 2 0 0 2 2 2 0 Protein phosphatase 1 binding Prok-RING_4 PF14447.1 CEP16274.1 - 0.061 12.8 0.2 0.061 12.8 0.2 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DUF4451 PF14616.1 CEP16274.1 - 4.5 7.0 10.2 1.5 8.5 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) DDE_3 PF13358.1 CEP16277.1 - 3.9e-23 81.8 0.0 1.1e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP16277.1 - 1e-05 25.6 0.1 4.3e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 CEP16277.1 - 1.2e-05 24.8 0.1 2.4e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.21 CEP16277.1 - 3.4e-05 23.9 0.0 7.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.1 CEP16277.1 - 0.002 18.0 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain PDCD2_C PF04194.8 CEP16280.1 - 9.6e-36 122.8 1.3 9.6e-36 122.8 0.9 3.1 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain DUF883 PF05957.8 CEP16281.1 - 0.0001 22.5 19.0 0.012 15.9 1.9 3.2 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 CEP16281.1 - 0.0029 17.9 25.7 1.2 9.5 1.9 4.2 1 1 1 2 2 2 1 YtxH-like protein Apolipoprotein PF01442.13 CEP16281.1 - 0.0051 16.3 10.4 0.024 14.1 7.2 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain EFG_IV PF03764.13 CEP16281.1 - 0.013 15.0 1.9 7.2 6.1 0.0 3.4 2 1 1 3 3 3 0 Elongation factor G, domain IV PRKCSH-like PF12999.2 CEP16281.1 - 0.047 13.2 14.5 0.054 13.0 1.6 3.1 1 1 2 3 3 3 0 Glucosidase II beta subunit-like Rsd_AlgQ PF04353.8 CEP16281.1 - 0.12 12.0 4.1 0.14 11.8 0.8 2.0 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Seryl_tRNA_N PF02403.17 CEP16281.1 - 0.13 12.2 24.2 0.32 11.0 4.9 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ISG65-75 PF11727.3 CEP16281.1 - 0.16 10.9 25.0 0.027 13.5 9.7 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein Herpes_UL6 PF01763.11 CEP16281.1 - 0.19 9.8 7.0 0.23 9.5 4.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Nbl1_Borealin_N PF10444.4 CEP16281.1 - 0.21 10.9 2.1 2.7 7.4 0.1 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Dynein_light PF01221.13 CEP16281.1 - 0.22 11.5 12.7 0.71 9.9 0.7 3.7 2 1 2 4 4 4 0 Dynein light chain type 1 eIF3_p135 PF12807.2 CEP16281.1 - 0.24 11.3 7.2 0.55 10.1 5.0 1.7 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 PMC2NT PF08066.7 CEP16281.1 - 0.31 11.3 7.1 7.8 6.8 0.4 2.9 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF948 PF06103.6 CEP16281.1 - 0.79 9.6 15.0 3.9 7.4 0.5 3.3 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIVA PF05103.8 CEP16281.1 - 1.4 8.9 24.2 13 5.7 8.0 2.7 1 1 2 3 3 3 0 DivIVA protein DUF1664 PF07889.7 CEP16281.1 - 1.6 8.5 13.1 2.2 8.0 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) LEA_4 PF02987.11 CEP16281.1 - 1.9 8.3 25.4 1.1 9.1 1.5 5.3 3 2 1 4 4 4 0 Late embryogenesis abundant protein CBFD_NFYB_HMF PF00808.18 CEP16281.1 - 3.4 7.7 7.1 1.1 9.3 0.6 3.1 2 2 1 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_S64 PF08192.6 CEP16281.1 - 3.7 5.7 13.3 4.4 5.5 9.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 Atg14 PF10186.4 CEP16281.1 - 4.3 6.1 15.6 29 3.4 10.6 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Dor1 PF04124.7 CEP16281.1 - 5.6 5.3 8.6 8.8 4.6 5.9 1.3 1 1 0 1 1 1 0 Dor1-like family Neur_chan_memb PF02932.11 CEP16281.1 - 6.7 6.5 9.5 15 5.3 6.6 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WXG100 PF06013.7 CEP16281.1 - 9.5 6.3 10.2 4.6 7.3 3.4 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF1674 PF07896.7 CEP16282.1 - 1.1e-14 54.3 3.0 1.4e-14 53.9 2.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Ebp2 PF05890.7 CEP16282.1 - 0.086 12.1 0.8 0.11 11.8 0.6 1.0 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 MBOAT PF03062.14 CEP16283.1 - 1.6e-23 83.3 17.2 2.7e-23 82.5 11.9 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Adipogenin PF15202.1 CEP16283.1 - 0.6 10.0 0.1 0.6 10.0 0.0 2.6 3 0 0 3 3 3 0 Adipogenin ACOX PF01756.14 CEP16284.1 - 5.7e-30 104.0 0.0 1.3e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEP16284.1 - 3.3e-20 72.6 0.2 6.9e-20 71.5 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEP16284.1 - 3.8e-09 35.9 0.0 9.1e-09 34.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEP16284.1 - 7.2e-05 22.9 0.1 0.014 15.4 0.0 4.0 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain E3_UbLigase_EDD PF11547.3 CEP16284.1 - 0.0019 17.6 0.5 0.14 11.6 0.1 2.6 2 0 0 2 2 2 1 E3 ubiquitin ligase EDD Nuc_sug_transp PF04142.10 CEP16285.1 - 3.3e-07 29.6 0.2 6.7e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CEP16285.1 - 0.012 15.6 5.6 0.012 15.6 3.9 3.4 4 0 0 4 4 4 0 EamA-like transporter family Cyt-b5 PF00173.23 CEP16286.1 - 1e-24 86.0 0.1 1.4e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BAR_2 PF10455.4 CEP16286.1 - 0.13 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Gln-synt_C PF00120.19 CEP16287.1 - 9e-59 198.7 0.0 1.1e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain UDPGP PF01704.13 CEP16288.1 - 2.1e-59 201.0 0.0 3e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CEP16288.1 - 0.01 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain RasGEF PF00617.14 CEP16289.1 - 9.4e-40 136.3 4.5 9.4e-40 136.3 3.1 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CEP16289.1 - 1.8e-16 60.1 0.2 1.8e-16 60.1 0.2 3.6 4 0 0 4 4 4 1 RasGEF N-terminal motif NRN1 PF15056.1 CEP16289.1 - 0.052 13.5 0.5 0.83 9.6 0.0 2.9 3 0 0 3 3 3 0 Neuritin protein family Cylicin_N PF15241.1 CEP16290.1 - 0.049 13.5 2.3 0.064 13.1 1.6 1.1 1 0 0 1 1 1 0 Cylicin N-terminus Shugoshin_N PF07558.6 CEP16290.1 - 0.051 13.2 1.7 0.093 12.4 0.1 2.3 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region Staphostatin_B PF09023.5 CEP16290.1 - 0.091 12.5 0.2 8.1 6.3 0.0 2.1 1 1 1 2 2 2 0 Staphostatin B Nucleotid_trans PF03407.11 CEP16291.1 - 1.2e-10 41.5 0.1 1.7e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF948 PF06103.6 CEP16291.1 - 0.014 15.2 0.0 0.054 13.3 0.0 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-C2H2_4 PF13894.1 CEP16293.1 - 0.016 15.4 0.2 0.016 15.4 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger A2L_zn_ribbon PF08792.5 CEP16293.1 - 0.061 12.7 1.5 0.16 11.4 1.0 1.7 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-C2H2 PF00096.21 CEP16293.1 - 0.063 13.6 0.4 0.19 12.1 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.2 CEP16293.1 - 0.076 13.2 0.5 0.22 11.7 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PBP1_TM PF14812.1 CEP16294.1 - 0.066 13.5 0.5 0.076 13.3 0.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_IS1595 PF12762.2 CEP16296.1 - 3.3e-25 88.6 0.2 9.7e-25 87.1 0.0 1.8 2 0 0 2 2 2 1 ISXO2-like transposase domain TRAP_alpha PF03896.11 CEP16297.1 - 0.031 13.2 4.4 0.04 12.9 3.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 CEP16297.1 - 0.051 13.8 9.5 0.098 12.9 6.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRN3 PF05327.6 CEP16297.1 - 2 6.4 5.9 2.4 6.1 4.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 CEP16297.1 - 3.8 7.0 13.5 6.1 6.4 9.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Enterotoxin_b PF01376.13 CEP16298.1 - 0.027 14.3 0.0 0.085 12.7 0.0 1.7 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain DUF4542 PF15075.1 CEP16299.1 - 0.021 14.7 0.3 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) Vfa1 PF08432.5 CEP16300.1 - 0.78 9.7 10.2 0.88 9.5 7.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CBF PF03914.12 CEP16300.1 - 0.93 8.9 2.6 1.2 8.5 1.8 1.3 1 0 0 1 1 1 0 CBF/Mak21 family DUF1510 PF07423.6 CEP16300.1 - 1.3 8.3 15.3 1.4 8.2 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 CEP16300.1 - 1.4 6.7 22.1 1.6 6.5 15.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 CEP16300.1 - 1.6 7.3 25.8 1.9 7.0 17.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 CEP16300.1 - 2.1 6.2 14.9 2.2 6.2 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 CEP16300.1 - 2.6 7.2 15.4 2.5 7.2 10.7 1.1 1 0 0 1 1 1 0 NOA36 protein YqfQ PF14181.1 CEP16300.1 - 2.6 8.0 4.5 2.9 7.9 3.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein Daxx PF03344.10 CEP16300.1 - 2.8 6.3 19.9 2.8 6.3 13.8 1.0 1 0 0 1 1 1 0 Daxx Family RNA_pol_Rpc4 PF05132.9 CEP16300.1 - 3.5 7.6 5.0 3.7 7.5 3.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CobT PF06213.7 CEP16300.1 - 3.7 6.6 18.6 4.3 6.3 12.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 CEP16300.1 - 6.5 5.7 15.7 6.8 5.6 10.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.3 CEP16300.1 - 7.7 5.4 7.4 7.1 5.5 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sigma70_ner PF04546.8 CEP16300.1 - 8.2 5.9 17.2 9.6 5.7 11.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.7 CEP16300.1 - 8.2 5.5 20.0 8.7 5.5 13.9 1.1 1 0 0 1 1 1 0 SDA1 VID27 PF08553.5 CEP16300.1 - 9.7 4.2 17.6 10 4.2 12.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein ATHILA PF03078.10 CEP16300.1 - 9.9 4.6 7.3 9.5 4.6 5.0 1.0 1 0 0 1 1 1 0 ATHILA ORF-1 family AAA PF00004.24 CEP16301.1 - 1.6e-82 274.2 0.0 2.8e-40 137.5 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEP16301.1 - 1.2e-11 44.9 0.1 8e-05 22.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CEP16301.1 - 2.5e-11 43.4 0.2 5.3e-06 26.1 0.0 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEP16301.1 - 2.8e-11 42.9 0.0 0.00027 20.0 0.0 3.7 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CEP16301.1 - 2.9e-10 40.3 0.7 4.2e-05 23.6 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CEP16301.1 - 7.7e-10 38.7 0.0 2.8e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEP16301.1 - 4.4e-09 37.1 0.0 0.002 18.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 CEP16301.1 - 6.7e-09 35.8 0.0 0.00039 20.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Kdo PF06293.9 CEP16301.1 - 1.5e-08 33.9 0.0 3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CEP16301.1 - 6.5e-08 32.0 0.1 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TIP49 PF06068.8 CEP16301.1 - 7.5e-08 31.4 0.2 0.013 14.2 0.1 2.8 2 1 0 2 2 2 2 TIP49 C-terminus NTPase_1 PF03266.10 CEP16301.1 - 4.4e-07 29.7 0.0 0.017 14.8 0.0 3.4 3 0 0 3 3 3 2 NTPase AAA_25 PF13481.1 CEP16301.1 - 8.9e-07 28.5 0.4 0.0035 16.7 0.0 3.3 2 1 1 3 3 3 1 AAA domain APH PF01636.18 CEP16301.1 - 1.4e-06 28.2 0.0 2.4e-05 24.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RNA_helicase PF00910.17 CEP16301.1 - 2e-06 27.9 0.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 CEP16301.1 - 2.6e-06 27.3 0.3 0.097 12.3 0.0 3.9 3 2 1 4 4 4 2 Archaeal ATPase Pkinase_Tyr PF07714.12 CEP16301.1 - 4.6e-06 25.8 0.1 8e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CEP16301.1 - 6.5e-06 25.6 0.0 1.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family AAA_3 PF07726.6 CEP16301.1 - 6.9e-06 25.7 0.0 0.03 13.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CEP16301.1 - 2.3e-05 24.1 0.1 0.23 11.0 0.0 3.4 2 1 0 3 3 3 1 NACHT domain AAA_24 PF13479.1 CEP16301.1 - 3.4e-05 23.5 0.3 0.061 12.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CEP16301.1 - 6.7e-05 22.5 0.3 0.53 10.0 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain AAA_33 PF13671.1 CEP16301.1 - 8.6e-05 22.4 0.0 0.016 15.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CEP16301.1 - 8.9e-05 21.9 0.1 0.0075 15.6 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein Rad17 PF03215.10 CEP16301.1 - 0.00012 20.8 0.1 0.0033 16.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 CEP16301.1 - 0.00017 21.8 0.0 0.57 10.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.7 CEP16301.1 - 0.00078 18.5 0.0 0.81 8.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 CEP16301.1 - 0.0013 19.0 0.0 0.79 10.0 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.1 CEP16301.1 - 0.0025 17.7 0.1 1 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.11 CEP16301.1 - 0.0027 16.5 0.0 0.12 11.1 0.0 2.3 2 0 0 2 2 2 1 AFG1-like ATPase EcKinase PF02958.15 CEP16301.1 - 0.0029 16.7 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF815 PF05673.8 CEP16301.1 - 0.0032 16.4 0.0 0.68 8.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 CEP16301.1 - 0.0036 16.4 0.2 1.7 7.7 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Choline_kinase PF01633.15 CEP16301.1 - 0.0048 16.5 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase KAP_NTPase PF07693.9 CEP16301.1 - 0.0093 14.9 0.1 0.85 8.5 0.0 2.9 2 1 0 2 2 2 1 KAP family P-loop domain AAA_11 PF13086.1 CEP16301.1 - 0.0097 15.5 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CEP16301.1 - 0.012 14.5 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 CEP16301.1 - 0.014 15.0 0.0 3.7 7.1 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 CEP16301.1 - 0.019 14.4 0.1 2 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain Bac_DnaA PF00308.13 CEP16301.1 - 0.02 14.5 0.0 0.62 9.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial dnaA protein WaaY PF06176.6 CEP16301.1 - 0.021 14.0 0.1 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF258 PF03193.11 CEP16301.1 - 0.024 13.8 0.0 2.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 CEP16301.1 - 0.068 12.6 0.0 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 CEP16301.1 - 0.1 12.1 0.0 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CEP16301.1 - 0.12 11.8 0.6 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Med7 PF05983.6 CEP16302.1 - 4.5e-49 166.3 1.9 5.2e-49 166.1 1.3 1.0 1 0 0 1 1 1 1 MED7 protein Ribonucleas_3_3 PF14622.1 CEP16303.1 - 0.012 15.5 1.0 0.21 11.5 0.7 2.3 1 1 0 1 1 1 0 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CEP16303.1 - 0.016 15.6 0.3 0.031 14.7 0.2 1.7 1 1 0 1 1 1 0 Ribonuclease III domain PBP1_TM PF14812.1 CEP16304.1 - 1.2 9.5 13.5 4.5 7.6 1.9 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lipase_3 PF01764.20 CEP16306.1 - 0.01 15.4 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) ACT_7 PF13840.1 CEP16307.1 - 1.4e-23 82.1 0.0 1.4e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 ACT domain Ricin_B_lectin PF00652.17 CEP16308.1 - 1.3e-17 63.9 0.2 7.8e-09 35.6 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP16308.1 - 7.2e-14 52.0 1.0 2.7e-08 34.1 0.1 2.7 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF4176 PF13780.1 CEP16308.1 - 0.03 14.0 0.4 7.1 6.4 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4176) Motile_Sperm PF00635.21 CEP16310.1 - 7.4e-17 60.9 0.3 9e-17 60.6 0.2 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Arrestin_C PF02752.17 CEP16311.1 - 3.6e-08 33.6 1.0 9.6e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP16311.1 - 6.8e-08 32.4 0.0 2e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CEP16311.1 - 5.1e-05 22.8 0.1 0.00029 20.4 0.0 2.1 1 1 1 2 2 2 1 Arrestin_N terminal like Pkinase PF00069.20 CEP16312.1 - 3.9e-57 193.3 0.0 7.4e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16312.1 - 2.1e-23 82.7 0.0 3e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP16312.1 - 0.00027 19.9 0.0 0.0013 17.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CEP16312.1 - 0.00095 18.9 0.1 0.0027 17.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Rxt3 PF08642.5 CEP16313.1 - 5.2e-23 81.4 0.9 1.7e-22 79.8 0.0 2.4 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 CEP16313.1 - 1.4e-05 25.0 0.7 0.0026 17.7 0.0 3.2 2 1 1 3 3 3 2 LCCL domain Ribosomal_L28e PF01778.12 CEP16314.1 - 1.6e-34 118.8 1.5 1.6e-34 118.8 1.0 2.1 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CEP16314.1 - 4e-24 84.6 22.4 4e-24 84.6 15.5 1.9 2 0 0 2 2 2 1 Mak16 protein C-terminal region TFIIA PF03153.8 CEP16314.1 - 0.011 15.6 5.4 0.013 15.4 3.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 CEP16314.1 - 8.6 4.7 21.9 12 4.2 15.2 1.1 1 0 0 1 1 1 0 Daxx Family CDC37_N PF03234.9 CEP16315.1 - 0.11 12.7 0.3 0.16 12.2 0.2 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Asp_protease_2 PF13650.1 CEP16316.1 - 1e-06 29.1 0.0 2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CEP16316.1 - 1.1e-06 28.6 0.1 2.3e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 CEP16316.1 - 4.3e-05 22.9 0.1 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 Ty3 transposon peptidase gag-asp_proteas PF13975.1 CEP16316.1 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-C4pol PF14260.1 CEP16316.1 - 0.072 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-CCHC PF00098.18 CEP16316.1 - 0.33 10.9 2.5 0.57 10.2 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Velvet PF11754.3 CEP16317.1 - 2.6e-29 102.2 15.0 1.1e-21 77.3 0.1 3.7 4 1 0 4 4 4 3 Velvet factor Acetyltransf_1 PF00583.19 CEP16318.1 - 1.3e-06 28.3 0.0 2.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP16318.1 - 1.7e-06 28.0 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP16318.1 - 4.4e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain S-antigen PF05756.6 CEP16319.1 - 0.048 13.6 0.8 0.12 12.3 0.5 1.7 1 0 0 1 1 1 0 S-antigen protein DUF2512 PF10710.4 CEP16319.1 - 0.88 9.0 4.5 1.8 8.0 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) TMEM18 PF14770.1 CEP16319.1 - 2.7 7.5 7.1 5.8 6.4 4.9 1.5 1 0 0 1 1 1 0 Transmembrane protein 18 DUF966 PF06136.8 CEP16321.1 - 1.8 7.9 7.7 2.4 7.4 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) IER PF05760.7 CEP16321.1 - 2.2 8.1 9.6 3.3 7.5 6.7 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) TFIIA PF03153.8 CEP16321.1 - 6.3 6.5 20.1 9.2 6.0 13.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.6 CEP16321.1 - 7.5 4.2 16.1 9.7 3.9 11.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDE_3 PF13358.1 CEP16322.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2292 PF10055.4 CEP16322.1 - 0.92 8.8 3.4 0.34 10.2 0.5 1.7 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) Mito_carr PF00153.22 CEP16323.1 - 7.5e-66 217.8 0.5 1.2e-22 79.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_2 PF03446.10 CEP16324.1 - 8.5e-44 149.2 0.5 1.2e-43 148.7 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CEP16324.1 - 2.2e-33 114.9 0.0 3.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 CEP16324.1 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CEP16324.1 - 4e-05 23.3 0.7 0.00072 19.2 0.6 2.6 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CEP16324.1 - 0.0003 20.2 3.2 0.049 13.0 0.3 2.6 2 1 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 CEP16324.1 - 0.00053 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 CEP16324.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 CEP16324.1 - 0.0028 16.8 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CEP16324.1 - 0.01 15.5 0.0 0.036 13.8 0.0 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 CEP16324.1 - 0.012 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain rRNA_methylase PF06962.7 CEP16324.1 - 0.043 13.5 0.1 0.065 12.9 0.1 1.2 1 0 0 1 1 1 0 Putative rRNA methylase GFO_IDH_MocA PF01408.17 CEP16324.1 - 0.046 14.2 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.4 CEP16324.1 - 0.049 13.3 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Rossmann-like domain PDH PF02153.12 CEP16324.1 - 0.1 11.4 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase CoA_binding PF02629.14 CEP16324.1 - 0.13 12.8 0.6 0.29 11.6 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain SWIM PF04434.12 CEP16325.1 - 0.003 16.9 0.1 0.0055 16.1 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger WHIM2 PF15613.1 CEP16326.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 EMP70 PF02990.11 CEP16327.1 - 1.9e-162 541.3 16.2 2.4e-162 541.0 11.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4231 PF14015.1 CEP16327.1 - 0.48 10.4 6.5 25 4.8 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) EVC2_like PF12297.3 CEP16327.1 - 1.5 7.3 2.6 15 4.0 1.3 2.0 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein OPT PF03169.10 CEP16328.1 - 1.7e-189 631.3 57.8 2.1e-189 631.0 40.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cytochrom_C_2 PF01322.15 CEP16329.1 - 0.01 16.3 0.4 0.018 15.5 0.3 1.4 1 0 0 1 1 1 0 Cytochrome C' PDEase_I_N PF08499.7 CEP16330.1 - 0.052 13.4 0.5 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal SWM_repeat PF13753.1 CEP16331.1 - 0.00022 20.3 0.1 0.016 14.2 0.0 2.3 2 0 0 2 2 2 2 Putative flagellar system-associated repeat I-set PF07679.11 CEP16331.1 - 0.00032 20.4 0.0 27 4.7 0.0 5.1 5 0 0 5 5 5 3 Immunoglobulin I-set domain DUF1918 PF08940.6 CEP16331.1 - 0.0092 15.3 0.7 15 5.0 0.0 5.0 6 0 0 6 6 6 1 Domain of unknown function (DUF1918) Na_Ca_ex PF01699.19 CEP16332.1 - 9.3e-41 138.7 42.9 1.4e-22 79.7 9.8 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DAO PF01266.19 CEP16337.1 - 2.2e-16 59.7 0.0 1.6e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEP16337.1 - 0.002 18.2 0.0 0.0045 17.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP16337.1 - 0.0078 16.6 0.2 0.032 14.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP16337.1 - 0.0084 16.1 0.2 0.025 14.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP16337.1 - 0.014 15.3 0.0 0.023 14.5 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CEP16337.1 - 0.042 13.8 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.19 CEP16337.1 - 0.052 12.3 0.1 0.099 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 CEP16337.1 - 0.079 11.9 0.1 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Aa_trans PF01490.13 CEP16339.1 - 2.9e-80 269.7 35.7 3.7e-80 269.3 24.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YbgT_YccB PF08173.6 CEP16340.1 - 0.024 14.4 1.0 0.024 14.4 0.7 3.0 3 0 0 3 3 3 0 Membrane bound YbgT-like protein DHQ_synthase PF01761.15 CEP16341.1 - 1.1e-91 306.3 0.0 1.7e-91 305.7 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CEP16341.1 - 1e-45 156.1 0.0 2.3e-45 154.9 0.0 1.6 2 0 0 2 2 2 1 Type I 3-dehydroquinase Fe-ADH_2 PF13685.1 CEP16341.1 - 3e-07 30.0 0.0 5.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase RVT_1 PF00078.22 CEP16342.1 - 2.5e-12 46.6 0.4 3.2e-12 46.2 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MRP-S31 PF15433.1 CEP16343.1 - 0.036 13.4 0.4 0.042 13.2 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 MbeB_N PF04837.7 CEP16343.1 - 0.1 12.7 2.2 1.3 9.1 0.6 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region FlaC_arch PF05377.6 CEP16343.1 - 0.13 12.1 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_S7e PF01251.13 CEP16343.1 - 0.15 11.5 0.3 0.35 10.3 0.2 1.6 1 1 1 2 2 2 0 Ribosomal protein S7e Prefoldin_2 PF01920.15 CEP16343.1 - 0.28 10.9 1.7 6.8 6.5 0.4 2.1 2 0 0 2 2 2 0 Prefoldin subunit Pkinase PF00069.20 CEP16344.1 - 4.6e-49 166.9 0.0 2.1e-42 145.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16344.1 - 1.2e-14 54.0 0.0 1.4e-12 47.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEP16344.1 - 0.00072 18.5 0.0 0.0067 15.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CEP16344.1 - 0.054 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3069 PF11269.3 CEP16344.1 - 0.16 12.0 0.3 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) F-box-like PF12937.2 CEP16345.1 - 1.1e-11 44.3 1.8 2.5e-11 43.1 0.9 1.9 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 CEP16345.1 - 1.3e-11 43.9 8.1 1.3e-06 28.0 0.6 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.28 CEP16345.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain UPF0542 PF15086.1 CEP16345.1 - 0.098 12.3 1.2 0.45 10.2 0.7 2.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0542 PH PF00169.24 CEP16346.1 - 6.3e-21 74.5 0.5 1.7e-20 73.1 0.3 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 CEP16346.1 - 6.8e-16 57.8 0.0 1.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 CEP16346.1 - 8e-13 47.7 0.0 1.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 CEP16346.1 - 1.6e-12 47.3 0.1 4.4e-12 45.9 0.0 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 CEP16346.1 - 9e-12 44.1 0.3 2.2e-11 42.9 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP16346.1 - 3.1e-09 36.1 0.2 5.6e-09 35.3 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 CEP16346.1 - 8.6e-08 32.4 4.0 6.5e-06 26.3 2.8 3.0 1 1 0 1 1 1 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 CEP16346.1 - 0.0016 18.4 0.1 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_8 PF15409.1 CEP16346.1 - 0.0021 18.0 0.5 0.0086 16.1 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_PNT PF02198.11 CEP16346.1 - 0.0028 17.3 0.2 0.033 13.9 0.0 2.3 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain CH PF00307.26 CEP16346.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 0 Calponin homology (CH) domain PH_3 PF14593.1 CEP16346.1 - 0.015 15.1 0.3 0.035 13.9 0.2 1.5 1 0 0 1 1 1 0 PH domain PfkB PF00294.19 CEP16347.1 - 7e-59 199.4 0.2 8.5e-59 199.1 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CEP16347.1 - 0.039 13.1 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase HMA PF00403.21 CEP16348.1 - 2.5e-57 190.8 0.1 2.5e-13 49.9 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 CEP16348.1 - 1.9e-46 157.9 2.8 4e-46 156.8 1.9 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEP16348.1 - 2.3e-41 142.5 0.0 4.6e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP16348.1 - 6.2e-16 59.1 0.0 2.5e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP16348.1 - 0.0026 17.3 4.2 0.019 14.5 0.7 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.1 CEP16348.1 - 0.0051 16.7 0.5 4.8 7.2 0.0 3.4 3 0 0 3 3 3 1 Papain fold toxin 2 Toxin-deaminase PF14424.1 CEP16348.1 - 0.18 11.7 3.2 3.4 7.6 0.2 3.2 3 0 0 3 3 3 0 The BURPS668_1122 family of deaminases Rad52_Rad22 PF04098.10 CEP16350.1 - 9.9e-49 165.0 1.3 2.9e-48 163.5 0.0 2.0 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 CEP16350.1 - 0.074 11.2 26.8 0.092 10.9 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-protein PF00469.15 CEP16350.1 - 0.091 12.1 1.4 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef TFIIA PF03153.8 CEP16350.1 - 0.12 12.2 17.4 0.15 11.9 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 CEP16350.1 - 0.35 9.7 8.1 0.44 9.4 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.2 CEP16350.1 - 1.7 6.2 5.1 2.2 5.8 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 CEP16351.1 - 1.4e-13 50.1 29.2 4.1e-06 26.4 0.4 6.8 7 1 0 7 7 7 4 WD domain, G-beta repeat RWD PF05773.17 CEP16351.1 - 0.00048 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-ribbon_3 PF13248.1 CEP16351.1 - 0.0035 16.4 3.4 0.074 12.2 0.4 2.5 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CEP16351.1 - 0.013 15.0 7.4 1.1 8.7 2.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CEP16351.1 - 1.2 9.0 15.1 0.56 10.0 8.6 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2 PF00096.21 CEP16352.1 - 0.12 12.7 1.5 0.21 12.0 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-CCHC PF00098.18 CEP16353.1 - 4.6e-05 23.1 3.4 7.1e-05 22.5 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CEP16353.1 - 0.0016 18.1 1.9 0.0045 16.6 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CEP16353.1 - 0.18 11.5 1.5 0.45 10.2 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Exo_endo_phos_2 PF14529.1 CEP16356.1 - 5.8e-07 29.1 0.2 2.6e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP16356.1 - 2.5e-06 27.5 0.2 3.8e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 CEP16356.1 - 0.12 12.3 0.4 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 FlxA-like protein RVT_1 PF00078.22 CEP16357.1 - 1.8e-26 92.8 0.0 2.4e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S21 PF00716.12 CEP16358.1 - 0.025 13.9 3.8 0.03 13.6 2.7 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) ECM1 PF05782.6 CEP16358.1 - 0.032 12.9 3.2 0.036 12.7 2.2 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Dehydrin PF00257.14 CEP16358.1 - 0.23 11.7 8.6 0.28 11.4 6.0 1.1 1 0 0 1 1 1 0 Dehydrin DUF605 PF04652.11 CEP16358.1 - 2.8 7.2 17.2 3.6 6.8 11.9 1.0 1 0 0 1 1 1 0 Vta1 like Pneumo_att_G PF05539.6 CEP16358.1 - 5.1 6.3 12.7 5.7 6.2 8.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Hamartin PF04388.7 CEP16358.1 - 8.4 4.9 7.7 8.5 4.9 5.4 1.1 1 0 0 1 1 1 0 Hamartin protein OrfB_Zn_ribbon PF07282.6 CEP16359.1 - 9.5e-11 41.2 1.1 2.1e-10 40.1 0.8 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain UPF0081 PF03652.10 CEP16359.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) FAR1 PF03101.10 CEP16361.1 - 1.1e-06 29.0 0.3 1.1e-06 29.0 0.2 2.4 2 0 0 2 2 2 1 FAR1 DNA-binding domain F-box PF00646.28 CEP16362.1 - 0.00036 20.1 0.2 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 CEP16362.1 - 0.0015 18.4 0.8 0.0015 18.4 0.6 2.2 2 0 0 2 2 2 1 PRANC domain Homez PF11569.3 CEP16362.1 - 0.0094 14.9 0.4 0.097 11.7 0.4 2.2 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Fucose_iso_N2 PF07882.7 CEP16362.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain GBP_repeat PF02526.9 CEP16362.1 - 0.026 13.8 0.7 0.092 12.1 0.4 2.0 2 0 0 2 2 2 0 Glycophorin-binding protein PK_C PF02887.11 CEP16362.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain F-box-like PF12937.2 CEP16362.1 - 0.073 12.8 0.2 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like Acetyltransf_3 PF13302.1 CEP16363.1 - 1.1e-18 67.7 0.0 1.2e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEP16363.1 - 0.0025 17.7 0.0 0.0038 17.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP16363.1 - 0.03 14.3 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RRM_1 PF00076.17 CEP16364.1 - 2.5e-20 71.8 0.1 7.8e-15 54.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16364.1 - 7e-19 67.5 0.1 6e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16364.1 - 4.5e-08 32.8 0.1 4.7e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_CA PF00484.14 CEP16364.1 - 0.16 11.9 0.3 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 Carbonic anhydrase RdRP PF05183.7 CEP16365.1 - 3.7e-100 336.3 0.0 8e-87 292.2 0.0 2.6 1 1 1 2 2 2 2 RNA dependent RNA polymerase TroA PF01297.12 CEP16365.1 - 0.043 13.0 0.1 0.081 12.1 0.1 1.4 1 0 0 1 1 1 0 Periplasmic solute binding protein family LIM PF00412.17 CEP16366.1 - 5.2e-24 84.0 60.3 2.8e-11 43.3 1.6 6.0 5 1 0 5 5 5 5 LIM domain Ribosomal_L6 PF00347.18 CEP16367.1 - 8e-33 112.7 7.8 3.7e-18 65.7 2.4 2.0 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.7 CEP16367.1 - 0.022 14.8 1.7 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 YbbR-like protein Pkinase PF00069.20 CEP16368.1 - 5.7e-60 202.6 0.0 9.2e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16368.1 - 8e-32 110.3 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP16368.1 - 3.1e-11 42.7 0.0 5.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NAD_binding_6 PF08030.7 CEP16368.1 - 0.12 12.2 3.7 0.45 10.4 0.1 2.6 3 0 0 3 3 3 0 Ferric reductase NAD binding domain ZZ PF00569.12 CEP16369.1 - 6.7e-10 38.3 4.4 1.1e-09 37.6 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CEP16369.1 - 2.1e-06 27.6 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP16369.1 - 0.0002 21.3 0.1 0.00065 19.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Zn_ribbon_2 PF12674.2 CEP16369.1 - 0.066 13.5 1.5 0.21 11.9 1.1 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-UBR PF02207.15 CEP16369.1 - 0.15 11.7 5.8 0.55 9.9 4.0 1.9 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Adap_comp_sub PF00928.16 CEP16370.1 - 8.3e-68 228.3 0.0 1e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CEP16370.1 - 1.7e-08 34.2 0.3 6.4e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Pkinase PF00069.20 CEP16371.1 - 2.5e-16 59.6 0.0 5.3e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16371.1 - 0.00046 19.3 0.0 0.0009 18.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Insulin PF00049.13 CEP16371.1 - 0.046 14.5 0.4 0.16 12.7 0.1 2.0 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family Mad3_BUB1_I PF08311.7 CEP16371.1 - 0.33 10.7 4.2 1.4 8.6 0.0 3.5 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 FCH PF00611.18 CEP16373.1 - 1.9e-15 56.7 1.3 1.9e-15 56.7 0.9 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CEP16373.1 - 2.4e-10 39.8 0.0 4.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP16373.1 - 6.2e-09 35.1 0.1 1.2e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP16373.1 - 3.2e-05 23.3 0.0 6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DAO PF01266.19 CEP16374.1 - 4.9e-53 180.3 0.0 6.6e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP16374.1 - 2.5e-08 33.2 1.1 0.0035 16.2 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 CEP16374.1 - 4.1e-07 29.4 1.2 0.00031 19.9 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CEP16374.1 - 3.8e-05 22.9 1.1 0.00039 19.5 0.8 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CEP16374.1 - 0.009 15.9 0.4 0.031 14.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP16374.1 - 0.0095 16.0 0.5 0.79 9.7 0.0 3.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CEP16374.1 - 0.022 13.6 0.5 1.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 CEP16374.1 - 0.034 13.7 0.8 0.062 12.9 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 CEP16374.1 - 0.035 14.1 0.5 0.15 12.1 0.3 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain WD40 PF00400.27 CEP16375.1 - 5.6e-45 149.6 13.9 2.2e-10 40.0 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CEP16375.1 - 5.5e-06 26.2 0.3 0.11 12.1 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CEP16375.1 - 0.00077 17.7 0.3 0.0023 16.1 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CEP16375.1 - 0.0041 16.6 0.0 0.03 13.8 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain Polysacc_deac_1 PF01522.16 CEP16376.1 - 5e-27 93.9 0.0 1e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP16376.1 - 0.0042 16.0 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 tRNA_int_endo PF01974.12 CEP16377.1 - 7.6e-22 76.9 0.3 1.5e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 CEP16377.1 - 9.7e-08 31.4 0.1 1.9e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain GST_N_3 PF13417.1 CEP16378.1 - 6.8e-15 55.0 0.0 1.9e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP16378.1 - 3.3e-08 33.5 0.0 7.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP16378.1 - 3.2e-07 30.2 0.0 8.2e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Gly_transf_sug PF04488.10 CEP16378.1 - 7.9e-06 26.2 0.0 2.2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CEP16378.1 - 0.016 14.3 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein CENP-K PF11802.3 CEP16379.1 - 9.1e-13 48.0 2.7 9.1e-13 48.0 1.9 2.6 1 1 1 2 2 2 1 Centromere-associated protein K SYCE1 PF15233.1 CEP16379.1 - 0.91 9.4 12.9 1.2 9.0 5.0 2.9 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF1664 PF07889.7 CEP16379.1 - 1.9 8.3 6.8 0.42 10.4 1.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TAFII55_N PF04658.8 CEP16380.1 - 5.3e-48 162.5 0.4 5.3e-48 162.5 0.3 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region SGT1 PF07093.6 CEP16380.1 - 0.012 14.0 19.8 0.018 13.4 13.7 1.3 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.7 CEP16380.1 - 0.019 12.9 27.4 0.031 12.1 19.0 1.4 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.13 CEP16381.1 - 1.2e-46 158.7 0.2 2.8e-46 157.5 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP16381.1 - 9.8e-10 38.1 13.1 1.9e-09 37.2 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAI16-like PF10257.4 CEP16382.1 - 2.5e-76 256.8 1.6 4.4e-76 256.1 1.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF4357 PF14267.1 CEP16382.1 - 0.53 9.9 1.8 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) adh_short PF00106.20 CEP16383.1 - 8.9e-30 103.8 3.2 1.1e-29 103.4 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP16383.1 - 8.8e-28 97.6 0.1 1e-27 97.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP16383.1 - 2.8e-10 40.1 1.5 4.1e-10 39.5 1.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CEP16383.1 - 0.00038 20.1 1.2 0.00066 19.3 0.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CEP16383.1 - 0.00041 19.7 0.2 0.00071 19.0 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.1 CEP16383.1 - 0.064 12.8 0.3 0.11 12.1 0.2 1.3 1 1 0 1 1 1 0 Methyltransferase domain D123 PF07065.9 CEP16384.1 - 8.1e-104 346.8 4.4 9.8e-104 346.6 3.0 1.1 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 CEP16384.1 - 0.00021 21.1 0.1 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) Ras PF00071.17 CEP16385.1 - 1.1e-57 193.8 0.1 1.3e-57 193.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP16385.1 - 4.1e-18 66.0 0.0 6.4e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP16385.1 - 7.1e-13 48.1 0.0 8.8e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP16385.1 - 1.9e-06 27.1 0.0 2.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEP16385.1 - 2.5e-06 27.4 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP16385.1 - 1.3e-05 24.7 0.0 0.00049 19.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEP16385.1 - 0.00019 21.5 0.0 0.00027 21.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CEP16385.1 - 0.00087 18.5 0.1 0.0019 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CEP16385.1 - 0.0015 18.0 0.2 0.085 12.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CEP16385.1 - 0.0035 16.8 0.0 0.0059 16.0 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 CEP16385.1 - 0.0038 16.8 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 CEP16385.1 - 0.0039 16.2 0.5 0.015 14.3 0.0 2.0 3 0 0 3 3 3 1 Septin NTPase_1 PF03266.10 CEP16385.1 - 0.0042 16.8 0.0 0.0075 15.9 0.0 1.4 2 0 0 2 2 2 1 NTPase Arch_ATPase PF01637.13 CEP16385.1 - 0.005 16.5 0.3 0.0087 15.7 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 CEP16385.1 - 0.0063 16.2 0.2 0.02 14.6 0.0 1.9 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 CEP16385.1 - 0.0085 15.6 0.3 0.37 10.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CEP16385.1 - 0.01 15.2 0.2 0.033 13.6 0.1 1.7 1 1 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 CEP16385.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP16385.1 - 0.014 15.4 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 CEP16385.1 - 0.014 14.5 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 CEP16385.1 - 0.049 13.2 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 CEP16385.1 - 0.063 12.5 0.0 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 CEP16385.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DRY_EERY PF09750.4 CEP16386.1 - 2.8 8.0 0.0 2.8 8.0 0.0 3.3 4 0 0 4 4 4 0 Alternative splicing regulator ATP-synt_DE PF00401.15 CEP16386.1 - 4.1 7.3 7.9 0.15 11.9 0.7 2.3 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain GPI-anchored PF10342.4 CEP16387.1 - 0.00017 21.9 2.0 0.00017 21.9 1.4 2.7 2 2 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4203 PF13886.1 CEP16388.1 - 2.2e-09 37.0 26.2 4.9e-09 35.9 18.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) Herpes_UL3 PF03369.8 CEP16388.1 - 0.036 14.0 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL3 protein PWWP PF00855.12 CEP16389.1 - 4.9e-17 61.8 0.2 4.9e-17 61.8 0.1 2.2 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 CEP16389.1 - 1.3e-05 24.6 0.0 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PQ-loop PF04193.9 CEP16390.1 - 5.8e-22 77.0 9.6 4.4e-13 48.5 0.9 3.5 3 0 0 3 3 3 2 PQ loop repeat DUF3671 PF12420.3 CEP16390.1 - 1.8 8.5 6.1 3.3 7.7 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function 4HBT PF03061.17 CEP16391.1 - 8.1e-09 35.4 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily RNase_PH PF01138.16 CEP16392.1 - 2.5e-24 86.0 0.0 4.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CEP16392.1 - 3.8e-09 36.3 0.0 1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glyco_trans_2_3 PF13632.1 CEP16393.1 - 5.2e-17 62.1 0.6 1.1e-16 61.1 0.4 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 RCC1 PF00415.13 CEP16394.1 - 1.7e-19 69.7 0.3 0.00011 22.3 0.2 6.9 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEP16394.1 - 2e-14 52.7 18.7 5.9e-05 22.5 0.6 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 CEP16394.1 - 1.3e-07 31.1 0.3 2.8e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP16394.1 - 0.00027 20.4 0.4 0.00056 19.5 0.3 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 CEP16394.1 - 0.016 15.6 0.2 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MADF_DNA_bdg PF10545.4 CEP16395.1 - 0.025 14.7 0.3 0.22 11.7 0.0 2.3 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FYVE PF01363.16 CEP16396.1 - 3e-20 71.8 4.9 7e-20 70.7 3.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.18 CEP16396.1 - 0.0002 21.0 0.7 14 5.6 0.0 5.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat IBR PF01485.16 CEP16396.1 - 0.0011 18.7 1.9 0.0029 17.4 1.3 1.6 1 0 0 1 1 1 1 IBR domain FYVE_2 PF02318.11 CEP16396.1 - 0.066 13.1 2.7 0.24 11.2 1.9 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger C1_4 PF07975.7 CEP16396.1 - 0.11 12.4 7.3 0.33 10.9 5.1 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain DUF4060 PF13269.1 CEP16396.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) zf-RING_5 PF14634.1 CEP16396.1 - 9 6.1 13.1 7.7 6.3 7.3 2.3 2 1 0 2 2 2 0 zinc-RING finger domain CN_hydrolase PF00795.17 CEP16397.1 - 9.5e-31 106.5 0.0 1.1e-29 103.0 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase EF-hand_1 PF00036.27 CEP16398.1 - 2.2e-15 54.6 4.3 6.6e-05 21.9 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CEP16398.1 - 3e-13 49.6 7.4 4.7e-08 33.0 1.1 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 CEP16398.1 - 4.9e-13 48.4 2.5 0.00012 21.6 0.0 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CEP16398.1 - 1.5e-12 46.2 2.8 4.9e-05 22.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain ZZ PF00569.12 CEP16398.1 - 1.7e-10 40.2 6.2 2.9e-10 39.5 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_5 PF13202.1 CEP16398.1 - 4.4e-09 35.2 1.8 0.00035 19.7 0.0 3.8 3 0 0 3 3 3 2 EF hand C1_3 PF07649.7 CEP16398.1 - 3.1 7.9 6.4 5 7.2 4.5 1.4 1 0 0 1 1 1 0 C1-like domain DUF4611 PF15387.1 CEP16398.1 - 8.9 6.5 9.9 1.7 8.8 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3752 PF12572.3 CEP16399.1 - 4.5e-27 95.0 9.2 4.5e-27 95.0 6.4 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF3752) SCP1201-deam PF14428.1 CEP16401.1 - 0.052 13.2 1.3 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 SCP1.201-like deaminase RVT_1 PF00078.22 CEP16402.1 - 5.1e-10 39.0 0.3 3.7e-09 36.2 0.2 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3388 PF11868.3 CEP16402.1 - 0.0043 16.2 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) Asp_protease_2 PF13650.1 CEP16403.1 - 0.087 13.3 0.1 0.58 10.6 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Chromo PF00385.19 CEP16405.1 - 7.7e-09 35.1 1.8 1.7e-08 33.9 1.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP16405.1 - 0.038 13.6 0.2 0.038 13.6 0.2 2.9 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain HEAT PF02985.17 CEP16409.1 - 0.0092 15.9 0.0 16 5.9 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CEP16409.1 - 0.05 13.9 0.0 0.25 11.7 0.0 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Asp PF00026.18 CEP16410.1 - 8.2e-61 205.9 0.8 1.4e-60 205.2 0.6 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP16410.1 - 6.6e-12 45.6 1.2 2e-11 44.1 0.5 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEP16410.1 - 0.1 13.0 0.0 22 5.6 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease MULE PF10551.4 CEP16411.1 - 1e-07 32.0 0.2 3.4e-07 30.3 0.1 2.0 1 0 0 1 1 1 1 MULE transposase domain DUF2414 PF10309.4 CEP16412.1 - 0.04 13.6 0.1 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) Transposase_31 PF04754.7 CEP16412.1 - 0.04 13.2 0.0 0.093 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative transposase, YhgA-like DUF2887 PF11103.3 CEP16412.1 - 0.066 12.8 0.0 0.2 11.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2887) DDE_3 PF13358.1 CEP16413.1 - 7.8e-31 106.7 0.0 1.2e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP16413.1 - 5.1e-07 29.1 0.1 1e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP16413.1 - 1.9e-06 27.9 0.0 1.9e-05 24.8 0.0 2.4 1 1 1 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP16413.1 - 3.9e-06 27.5 0.3 8.7e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 CEP16413.1 - 3.9e-05 23.5 0.0 0.0007 19.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 CEP16413.1 - 0.00079 19.3 0.2 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.1 CEP16413.1 - 0.081 12.1 0.1 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Bromodomain PF00439.20 CEP16414.1 - 3.1e-42 142.3 1.2 6.1e-22 77.3 0.1 2.8 2 0 0 2 2 2 2 Bromodomain BBS1 PF14779.1 CEP16415.1 - 0.063 12.2 0.9 0.11 11.4 0.6 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 ArfGap PF01412.13 CEP16416.1 - 2.5e-35 120.7 0.1 2.5e-35 120.7 0.1 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 CEP16416.1 - 1e-12 48.1 0.1 1e-12 48.1 0.1 2.4 3 1 0 3 3 3 1 PH domain CENP-F_leu_zip PF10473.4 CEP16417.1 - 0.004 17.0 5.0 0.004 17.0 3.5 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Katanin_con80 PF13925.1 CEP16417.1 - 0.03 14.0 1.0 0.058 13.1 0.7 1.4 1 0 0 1 1 1 0 con80 domain of Katanin Sigma70_ner PF04546.8 CEP16417.1 - 2.2 7.8 18.4 1.8 8.1 1.1 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region Pkinase PF00069.20 CEP16418.1 - 9e-40 136.4 0.5 2.8e-20 72.5 0.3 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16418.1 - 5e-11 42.1 0.0 2.4e-08 33.4 0.0 3.3 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 CEP16418.1 - 0.00052 19.8 0.0 0.013 15.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family TPR_2 PF07719.12 CEP16418.1 - 0.038 13.8 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP16418.1 - 0.044 13.3 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP16418.1 - 0.048 13.3 0.0 0.2 11.3 0.0 2.0 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 CEP16418.1 - 0.15 12.7 0.5 1.1 10.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat O-FucT PF10250.4 CEP16420.1 - 0.048 12.7 1.3 0.077 12.0 0.3 1.9 2 1 1 3 3 3 0 GDP-fucose protein O-fucosyltransferase COX16 PF14138.1 CEP16421.1 - 3.1e-28 97.7 0.0 3.8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Glutaredoxin PF00462.19 CEP16422.1 - 3.8e-10 39.5 0.0 5.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF3666 PF12408.3 CEP16422.1 - 0.053 12.6 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Chaperone_III PF07824.7 CEP16422.1 - 0.11 12.4 0.0 3.4 7.5 0.0 2.1 1 1 1 2 2 2 0 Type III secretion chaperone domain RasGAP PF00616.14 CEP16423.1 - 1.1e-42 146.0 2.1 1.1e-42 146.0 1.4 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CEP16423.1 - 8.8e-30 103.2 1.8 1.9e-29 102.1 0.2 2.5 2 0 0 2 2 2 1 RasGAP C-terminus CH PF00307.26 CEP16423.1 - 2.1e-11 43.8 0.0 8.6e-11 41.8 0.0 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 CEP16423.1 - 0.074 12.7 2.1 0.25 11.0 0.1 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif CBFD_NFYB_HMF PF00808.18 CEP16424.1 - 1.2e-18 66.9 0.7 1.9e-18 66.2 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Suc_Fer-like PF06999.7 CEP16425.1 - 1.5e-23 84.0 1.8 1.8e-21 77.2 1.6 2.1 2 0 0 2 2 2 2 Sucrase/ferredoxin-like Sec2p PF06428.6 CEP16426.1 - 1.4e-16 60.1 9.0 1.4e-16 60.1 6.2 2.6 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Flagellin_C PF00700.16 CEP16426.1 - 0.05 13.7 5.2 1.6 8.9 0.9 2.9 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region Tho2 PF11262.3 CEP16426.1 - 0.14 11.1 19.3 0.018 14.1 4.6 3.0 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 DUF1826 PF08856.6 CEP16426.1 - 0.81 9.4 8.6 0.55 9.9 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) Reo_sigmaC PF04582.7 CEP16426.1 - 1 8.4 4.0 2.2 7.3 1.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 CEP16426.1 - 4.5 6.1 25.1 3.4 6.5 7.2 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CEP16426.1 - 9.2 5.8 30.7 3.6 7.1 12.6 2.5 1 1 1 2 2 2 0 IncA protein DUF4407 PF14362.1 CEP16426.1 - 9.4 5.0 13.5 19 4.0 5.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LRR_6 PF13516.1 CEP16427.1 - 1.1e-10 40.4 17.1 0.19 11.8 0.0 9.2 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.28 CEP16427.1 - 0.002 17.8 9.0 91 3.7 0.0 7.9 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 CEP16427.1 - 0.16 11.5 27.8 1.4 8.6 0.6 7.4 4 4 3 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP16427.1 - 0.7 9.6 24.4 2.4 7.9 0.3 6.1 4 3 3 7 7 7 0 Leucine rich repeat Sulfate_transp PF00916.15 CEP16428.1 - 0.0031 16.5 10.8 0.0031 16.5 7.5 2.6 1 1 0 2 2 2 1 Sulfate transporter family BenE PF03594.8 CEP16428.1 - 0.0055 15.3 2.5 0.0055 15.3 1.7 2.6 3 1 0 3 3 3 2 Benzoate membrane transport protein DUF3446 PF11928.3 CEP16428.1 - 0.1 12.8 10.6 0.28 11.4 4.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF4131 PF13567.1 CEP16428.1 - 1.3 8.3 0.0 1.3 8.3 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) COG6 PF06419.6 CEP16429.1 - 2.4e-159 531.4 5.0 2.7e-159 531.2 3.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 PspA_IM30 PF04012.7 CEP16429.1 - 0.06 12.7 4.7 0.52 9.6 1.2 3.2 2 1 1 3 3 3 0 PspA/IM30 family SlyX PF04102.7 CEP16429.1 - 0.13 12.7 2.1 0.42 11.0 0.4 2.8 2 0 0 2 2 2 0 SlyX Peptidase_C50 PF03568.12 CEP16430.1 - 3.3e-88 295.9 0.0 8.7e-88 294.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family C50 TPR_2 PF07719.12 CEP16430.1 - 0.00031 20.4 13.5 0.13 12.2 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat CHAT PF12770.2 CEP16430.1 - 0.0013 17.9 3.3 0.0019 17.4 0.0 2.6 3 0 0 3 3 3 1 CHAT domain TPR_1 PF00515.23 CEP16430.1 - 0.016 14.7 8.1 0.28 10.8 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2005 PF09407.5 CEP16430.1 - 0.033 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2005) TPR_12 PF13424.1 CEP16430.1 - 0.046 13.6 19.2 1.1 9.2 0.2 7.1 6 2 2 8 8 8 0 Tetratricopeptide repeat PB1 PF00564.19 CEP16431.1 - 2e-11 43.3 0.1 4.4e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 PB1 domain Zip PF02535.17 CEP16431.1 - 2.2 7.1 5.5 2.9 6.7 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 CEP16432.1 - 1.4e-66 224.3 0.1 3.1e-66 223.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16432.1 - 9.8e-28 96.9 0.0 1.2e-22 80.2 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEP16432.1 - 3e-08 32.9 0.6 0.0058 15.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CEP16432.1 - 0.00035 19.9 0.6 0.00087 18.6 0.4 1.7 1 0 0 1 1 1 1 RIO1 family Xpo1 PF08389.7 CEP16433.1 - 1.7e-40 138.2 0.9 4.1e-36 124.0 0.1 3.7 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.14 CEP16433.1 - 2.6e-05 24.0 2.3 0.00011 22.0 0.1 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CEP16433.1 - 0.053 13.8 0.0 9.9 6.5 0.0 3.5 3 1 0 3 3 3 0 HEAT repeats Sec1 PF00995.18 CEP16434.1 - 9.1e-111 371.2 0.1 1.3e-110 370.6 0.1 1.2 1 0 0 1 1 1 1 Sec1 family Transket_pyr PF02779.19 CEP16434.1 - 8.9e-46 155.6 0.0 1.6e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CEP16434.1 - 1.8e-38 131.2 0.0 4.9e-38 129.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Ammonium_transp PF00909.16 CEP16435.1 - 1.3e-96 323.4 33.7 2.1e-61 207.6 6.5 3.0 3 0 0 3 3 3 3 Ammonium Transporter Family PRMT5 PF05185.11 CEP16436.1 - 1.3e-10 40.7 0.0 1.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 CEP16436.1 - 6.1e-07 29.4 0.0 0.00028 20.9 0.0 2.5 1 1 0 2 2 2 2 Methyltransferase domain PrmA PF06325.8 CEP16436.1 - 2.8e-06 26.6 0.0 4.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CEP16436.1 - 7.7e-06 26.4 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP16436.1 - 0.00093 18.6 0.0 0.0024 17.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CEP16436.1 - 0.0016 18.1 0.0 0.003 17.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CEP16436.1 - 0.0036 16.7 0.1 0.67 9.3 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 CEP16436.1 - 0.0061 16.9 0.0 0.25 11.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP16436.1 - 0.0091 16.4 0.0 0.036 14.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP16436.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 CEP16436.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF4451 PF14616.1 CEP16441.1 - 2.5e-24 85.4 10.7 8.2e-24 83.7 7.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) WD40 PF00400.27 CEP16442.1 - 6.2e-58 190.7 19.1 8.6e-10 38.1 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP16442.1 - 4.6e-12 44.8 2.0 0.00022 19.5 0.1 4.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 CEP16442.1 - 6.7e-05 22.6 0.1 2.3 8.0 0.0 4.5 3 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 CEP16442.1 - 0.001 19.2 1.0 1.4 9.2 0.1 3.9 4 0 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.1 CEP16442.1 - 0.0091 15.4 0.2 0.15 11.5 0.2 2.7 1 1 1 2 2 2 1 PQQ-like domain Arylsulfotran_2 PF14269.1 CEP16442.1 - 0.0098 15.0 0.6 0.037 13.1 0.0 2.2 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) DUF1258 PF06869.7 CEP16442.1 - 0.053 12.5 0.1 4.6 6.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1258) zf-H2C2_2 PF13465.1 CEP16444.1 - 1.8e-09 37.4 10.4 1.5e-05 25.0 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP16444.1 - 7.6e-06 25.9 14.1 0.003 17.8 2.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP16444.1 - 0.00018 21.6 13.8 0.00066 19.8 1.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP16444.1 - 0.0044 17.1 4.4 0.008 16.2 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP16444.1 - 0.026 14.7 0.8 0.026 14.7 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Clat_adaptor_s PF01217.15 CEP16445.1 - 1.6e-27 95.9 1.4 2.1e-27 95.5 0.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3534 PF12053.3 CEP16446.1 - 0.0012 18.7 1.1 0.0037 17.1 0.4 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3534) RNA_pol_Rpb5_C PF01191.14 CEP16446.1 - 0.0074 15.8 0.0 0.024 14.2 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain ubiquitin PF00240.18 CEP16446.1 - 0.12 11.8 0.2 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family WD40 PF00400.27 CEP16447.1 - 5.9e-39 130.5 14.6 5.3e-10 38.7 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEP16447.1 - 0.0015 17.3 0.1 0.22 10.2 0.0 2.6 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 CEP16447.1 - 0.038 12.1 0.1 0.34 9.0 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PEPCK_ATP PF01293.15 CEP16449.1 - 2e-222 738.7 0.0 2.3e-222 738.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 CEP16449.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Gti1_Pac2 PF09729.4 CEP16450.1 - 2.1e-47 161.1 4.9 8.6e-39 133.0 0.4 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Nairo_nucleo PF02477.10 CEP16450.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein PP2C PF00481.16 CEP16451.1 - 5.4e-80 268.4 0.1 6.8e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Isochorismatase PF00857.15 CEP16452.1 - 4.9e-24 85.2 0.3 1e-23 84.1 0.2 1.5 1 1 0 1 1 1 1 Isochorismatase family Glyco_trans_4_2 PF13477.1 CEP16452.1 - 0.1 12.4 0.1 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF4566 PF15130.1 CEP16452.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) DUF2315 PF10231.4 CEP16453.1 - 3.9e-19 68.7 4.2 1.4e-13 50.8 0.2 2.2 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2315) WD40 PF00400.27 CEP16454.1 - 1e-52 174.1 18.1 2.7e-11 42.8 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CEP16454.1 - 1.5e-07 29.9 13.3 0.011 13.8 0.2 4.7 3 2 2 6 6 6 3 Nucleoporin Nup120/160 Jnk-SapK_ap_N PF09744.4 CEP16454.1 - 0.078 12.9 2.7 0.14 12.1 1.9 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF972 PF06156.8 CEP16454.1 - 0.16 12.3 4.1 0.065 13.5 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Prenyltransf PF01255.14 CEP16454.1 - 0.37 9.8 2.9 0.4 9.7 1.1 1.6 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase APG6 PF04111.7 CEP16454.1 - 1.6 7.6 7.9 0.3 10.1 2.6 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 LRR_6 PF13516.1 CEP16455.1 - 6.9e-11 41.0 18.8 0.3 11.2 0.0 10.5 10 0 0 10 10 10 3 Leucine Rich repeat F-box-like PF12937.2 CEP16455.1 - 3e-09 36.4 0.3 3e-09 36.4 0.2 3.1 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.2 CEP16455.1 - 1.6e-08 34.0 10.0 0.48 10.1 0.0 7.1 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) F-box PF00646.28 CEP16455.1 - 0.0019 17.7 0.2 0.0019 17.7 0.2 3.7 5 0 0 5 5 5 1 F-box domain CGGC PF08821.6 CEP16455.1 - 0.047 13.7 0.3 0.047 13.7 0.2 2.4 3 1 0 3 3 3 0 CGGC domain LRR_7 PF13504.1 CEP16455.1 - 2.7 8.5 19.9 10 6.8 0.1 7.4 8 1 0 8 8 8 0 Leucine rich repeat Snapin_Pallidin PF14712.1 CEP16457.1 - 1.7e-06 28.2 1.0 7.6e-06 26.1 0.7 2.1 2 0 0 2 2 2 1 Snapin/Pallidin RVT_1 PF00078.22 CEP16457.1 - 0.1 11.9 0.4 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) eIF-5_eIF-2B PF01873.12 CEP16458.1 - 1.7e-45 153.7 0.4 2.7e-45 153.0 0.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 CEP16458.1 - 0.0038 16.5 0.2 0.0077 15.5 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.1 CEP16458.1 - 0.012 15.9 0.3 0.03 14.6 0.2 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar SMC_hinge PF06470.8 CEP16458.1 - 0.11 12.4 0.3 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain zf-HYPF PF07503.7 CEP16458.1 - 0.11 11.8 0.2 17 4.9 0.0 2.4 2 0 0 2 2 2 0 HypF finger Zn-ribbon_8 PF09723.5 CEP16458.1 - 0.12 12.3 0.6 0.26 11.2 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Arc_trans_TRASH PF08394.5 CEP16458.1 - 6.8 6.9 6.9 9.1 6.5 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain Coatamer_beta_C PF07718.7 CEP16458.1 - 9.1 5.9 8.9 4.7 6.8 1.1 2.5 2 1 0 2 2 2 0 Coatomer beta C-terminal region FAR1 PF03101.10 CEP16459.1 - 0.00052 20.4 0.4 0.00052 20.4 0.3 2.1 1 1 1 2 2 2 1 FAR1 DNA-binding domain PAT1 PF09770.4 CEP16459.1 - 0.033 12.4 22.0 0.039 12.1 15.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF607 PF04678.8 CEP16459.1 - 2.1 8.2 5.9 2.8 7.8 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF607 AAA PF00004.24 CEP16460.1 - 2.3e-59 199.3 0.0 5.4e-42 143.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CEP16460.1 - 3.1e-26 91.2 0.3 6.8e-26 90.1 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CEP16460.1 - 3e-13 50.1 4.5 1e-06 28.8 0.0 4.3 4 1 1 5 5 3 2 AAA ATPase domain AAA_14 PF13173.1 CEP16460.1 - 2.1e-07 30.8 0.0 0.023 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEP16460.1 - 1.5e-06 29.0 0.0 0.0073 17.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CEP16460.1 - 4.8e-06 26.7 1.9 0.23 11.5 0.0 4.2 2 2 0 2 2 2 2 AAA domain DUF815 PF05673.8 CEP16460.1 - 3e-05 23.0 0.0 0.003 16.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 CEP16460.1 - 5e-05 22.9 1.0 0.31 10.8 0.2 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_33 PF13671.1 CEP16460.1 - 7.5e-05 22.6 0.0 0.054 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CEP16460.1 - 9.5e-05 21.4 0.1 0.002 17.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 CEP16460.1 - 0.0001 22.6 0.0 0.58 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CEP16460.1 - 0.00011 21.9 0.1 0.17 11.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CEP16460.1 - 0.00015 21.9 0.0 0.88 9.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 CEP16460.1 - 0.00022 21.0 0.0 0.67 9.6 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase RuvB_N PF05496.7 CEP16460.1 - 0.00031 19.8 0.0 0.0023 17.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 CEP16460.1 - 0.00035 20.1 0.0 0.46 9.9 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CEP16460.1 - 0.00056 18.8 0.0 1.4 7.7 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain NACHT PF05729.7 CEP16460.1 - 0.00063 19.4 3.3 0.56 9.8 0.5 3.9 3 1 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.1 CEP16460.1 - 0.0007 19.6 0.0 1.7 8.6 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 CEP16460.1 - 0.00077 18.6 0.0 0.71 8.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 CEP16460.1 - 0.0011 17.7 0.0 0.078 11.6 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 CEP16460.1 - 0.0019 17.7 0.0 0.4 10.1 0.0 2.8 2 1 1 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CEP16460.1 - 0.005 16.0 0.1 0.65 9.1 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CEP16460.1 - 0.0055 16.6 0.0 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CEP16460.1 - 0.0062 15.9 3.8 2.1 7.6 0.1 3.6 2 2 1 3 3 3 1 AAA domain NTPase_1 PF03266.10 CEP16460.1 - 0.0072 16.0 0.1 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_2 PF07724.9 CEP16460.1 - 0.0098 15.8 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA12 PF10443.4 CEP16460.1 - 0.01 14.3 0.0 0.021 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein AAA_24 PF13479.1 CEP16460.1 - 0.015 14.8 0.4 3.8 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CEP16460.1 - 0.018 14.5 0.1 0.32 10.5 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CEP16460.1 - 0.026 14.8 0.0 10 6.4 0.0 3.0 2 0 0 2 2 2 0 ABC transporter AAA_35 PF14516.1 CEP16460.1 - 0.026 13.1 0.0 0.086 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 CEP16460.1 - 0.029 13.8 0.8 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 CEP16460.1 - 0.038 13.1 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Cytidylate_kin2 PF13189.1 CEP16460.1 - 0.039 13.8 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_3 PF07726.6 CEP16460.1 - 0.043 13.4 0.0 1 8.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CEP16460.1 - 0.07 13.6 0.5 0.7 10.4 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein DUF2075 PF09848.4 CEP16460.1 - 0.075 11.9 0.3 2.9 6.7 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 CEP16460.1 - 0.088 12.4 0.1 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Peptidase_S9 PF00326.16 CEP16461.1 - 7.5e-55 185.4 0.5 7.5e-55 185.4 0.3 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEP16461.1 - 1.2e-11 44.5 0.2 4.8e-11 42.5 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP16461.1 - 5.5e-11 42.7 0.8 3.9e-10 40.0 0.2 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family SRF-TF PF00319.13 CEP16461.1 - 3.4e-09 35.8 0.1 6.6e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AXE1 PF05448.7 CEP16461.1 - 2.1e-06 26.4 0.0 4.5e-05 22.0 0.0 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Med15 PF09606.5 CEP16461.1 - 0.76 7.9 81.6 1.1 7.4 56.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Homeobox PF00046.24 CEP16462.1 - 1.4e-18 66.2 1.7 2.7e-18 65.3 1.2 1.5 1 0 0 1 1 1 1 Homeobox domain Occludin_ELL PF07303.8 CEP16464.1 - 0.015 16.0 0.2 1.2 9.9 0.0 2.3 2 1 0 2 2 2 0 Occludin homology domain DUF4414 PF14377.1 CEP16464.1 - 0.076 12.9 1.5 0.55 10.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) PolyA_pol PF01743.15 CEP16465.1 - 0.016 15.4 0.2 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 Poly A polymerase head domain RhoGAP PF00620.22 CEP16466.1 - 1.8e-37 128.3 0.1 4.9e-37 126.8 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CEP16466.1 - 1e-07 31.9 14.4 3.2e-07 30.3 1.0 3.1 3 0 0 3 3 3 2 LIM domain DUF1708 PF08101.6 CEP16466.1 - 0.001 18.0 2.4 0.0037 16.1 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1708) GCIP PF13324.1 CEP16467.1 - 3.6e-24 85.4 1.8 4.9e-24 85.0 1.2 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Transferase PF02458.10 CEP16467.1 - 0.0038 15.7 0.6 0.013 13.9 0.0 1.8 2 0 0 2 2 2 1 Transferase family DASH_Ask1 PF08655.5 CEP16469.1 - 0.11 12.3 0.1 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Ask1 Transket_pyr PF02779.19 CEP16470.1 - 2.5e-58 196.5 0.0 3.7e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CEP16470.1 - 1.6e-42 145.2 0.0 3.9e-42 144.0 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component TBCA PF02970.11 CEP16470.1 - 0.011 15.7 0.2 0.028 14.4 0.1 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A DnaJ-X PF14308.1 CEP16471.1 - 1.5e-50 171.2 8.3 1.5e-50 171.2 5.7 1.9 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CEP16471.1 - 4.5e-27 93.5 1.9 1.9e-26 91.5 1.3 2.1 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 CEP16472.1 - 9.7e-36 120.3 12.1 6.6e-08 32.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat PAT1 PF09770.4 CEP16472.1 - 0.0053 15.0 34.0 0.086 11.0 8.1 2.0 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CEP16472.1 - 0.0056 14.9 46.6 0.0057 14.9 11.4 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CEP16472.1 - 0.0088 16.0 20.7 0.018 15.0 2.5 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 CEP16472.1 - 0.014 14.7 8.6 0.048 13.0 1.1 2.3 2 0 0 2 2 2 0 Spt20 family Suf PF05843.9 CEP16472.1 - 0.48 10.1 20.0 0.99 9.0 5.0 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) US2 PF02476.10 CEP16472.1 - 0.51 10.8 5.5 0.19 12.2 0.9 2.2 2 0 0 2 2 2 0 US2 family TFIIA PF03153.8 CEP16472.1 - 2 8.2 27.1 1.7 8.5 6.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.6 CEP16472.1 - 5.6 4.6 11.9 6.6 4.4 7.9 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF1764 PF08576.5 CEP16472.1 - 9.9 7.0 14.2 7.2 7.4 3.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) AT_hook PF02178.14 CEP16473.1 - 1.1e-07 30.6 18.1 0.0062 16.0 1.9 3.9 3 0 0 3 3 3 3 AT hook motif Elong_Iki1 PF10483.4 CEP16473.1 - 1 8.6 3.5 1.3 8.3 2.5 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 Gag_spuma PF03276.9 CEP16473.1 - 1.7 6.8 9.4 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Tim17 PF02466.14 CEP16474.1 - 9.4e-09 35.3 0.3 1.3e-05 25.2 0.1 2.6 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family FeoB_C PF07664.7 CEP16474.1 - 0.084 12.3 0.3 1.3 8.5 0.1 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus MAT1 PF06391.8 CEP16474.1 - 0.17 11.4 0.1 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 FA_hydroxylase PF04116.8 CEP16475.1 - 5.8e-14 52.4 22.7 5.8e-14 52.4 15.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HlyIII PF03006.15 CEP16476.1 - 1.6e-39 135.6 16.1 2.1e-39 135.2 11.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related PSP94 PF05825.6 CEP16476.1 - 0.063 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) DUF485 PF04341.7 CEP16476.1 - 1.5 8.5 0.0 1.5 8.5 0.0 3.2 2 1 2 4 4 4 0 Protein of unknown function, DUF485 XPG_N PF00752.12 CEP16477.1 - 5.3e-35 119.7 0.0 2.4e-34 117.6 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 CEP16477.1 - 1.1e-24 86.3 0.0 5.1e-24 84.1 0.0 2.3 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CEP16477.1 - 0.011 15.9 0.3 0.18 12.0 0.0 3.0 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold IZUMO PF15005.1 CEP16477.1 - 0.076 13.0 0.2 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion Heme_oxygenase PF01126.15 CEP16478.1 - 6.4e-51 172.8 1.3 8.2e-51 172.4 0.9 1.1 1 0 0 1 1 1 1 Heme oxygenase HMA PF00403.21 CEP16479.1 - 2.2e-12 46.9 4.7 2.8e-12 46.6 3.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_S11 PF00411.14 CEP16479.1 - 0.015 15.5 0.1 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S11 DUF464 PF04327.7 CEP16479.1 - 0.027 14.7 0.2 0.04 14.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF464) Mito_carr PF00153.22 CEP16480.1 - 3.2e-42 142.1 4.7 9.3e-18 63.7 0.0 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein ThiS PF02597.15 CEP16480.1 - 2.1e-08 34.4 0.0 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 ThiS family DUF4581 PF15167.1 CEP16480.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) Galactosyl_T PF01762.16 CEP16481.1 - 3.1e-17 62.8 0.0 4.5e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.3 CEP16481.1 - 9.2e-09 35.1 11.0 9.8e-09 35.0 6.8 1.5 1 1 0 1 1 1 1 N-glycosylation protein Glyco_transf_21 PF13506.1 CEP16481.1 - 0.012 14.9 0.1 0.022 14.0 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 21 LRR_4 PF12799.2 CEP16482.1 - 0.0038 16.8 5.9 8.9 6.0 0.0 5.4 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP16482.1 - 0.0039 17.0 0.8 40 4.7 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat FlhC PF05280.6 CEP16482.1 - 0.16 11.4 1.4 0.41 10.0 1.0 1.7 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) LRR_6 PF13516.1 CEP16482.1 - 0.87 9.8 17.1 7.6 6.9 0.0 7.0 10 0 0 10 10 10 0 Leucine Rich repeat PBP1_TM PF14812.1 CEP16482.1 - 2 8.7 7.7 0.52 10.6 2.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRR_7 PF13504.1 CEP16482.1 - 2.3 8.7 11.7 93 3.9 0.0 7.0 9 0 0 9 9 9 0 Leucine rich repeat Ribosomal_L7Ae PF01248.21 CEP16483.1 - 1.7e-28 97.9 2.2 2.1e-28 97.6 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.17 CEP16485.1 - 6.8e-25 86.4 0.0 9.1e-13 47.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16485.1 - 9e-22 76.8 0.0 5.6e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16485.1 - 3.9e-20 71.4 0.3 5.4e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP16485.1 - 0.00099 18.9 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif DDE_3 PF13358.1 CEP16486.1 - 5.4e-21 74.8 0.0 1.6e-20 73.3 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP16486.1 - 0.0037 16.4 0.2 0.0089 15.1 0.1 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP16486.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain NAD_binding_10 PF13460.1 CEP16487.1 - 0.0081 16.1 0.0 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding ATP-sulfurylase PF01747.12 CEP16488.1 - 2.9e-86 288.2 0.1 3.9e-86 287.8 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CEP16488.1 - 7.1e-56 188.0 0.0 1.2e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 CEP16488.1 - 6.4e-52 175.3 0.0 1.2e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CEP16488.1 - 2.4e-05 24.2 0.5 4.7e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEP16488.1 - 0.0035 17.6 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CEP16488.1 - 0.015 14.5 0.0 0.034 13.3 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DUF3251 PF11622.3 CEP16488.1 - 0.13 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Fungal_trans PF04082.13 CEP16489.1 - 7.8e-20 70.8 4.2 8e-20 70.7 0.5 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1675 PF07897.6 CEP16489.1 - 0.048 13.5 3.1 0.099 12.5 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) 2-Hacid_dh_C PF02826.14 CEP16490.1 - 1.6e-49 167.4 0.0 3e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEP16490.1 - 2.5e-35 120.8 0.0 3.4e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CEP16490.1 - 0.00035 20.4 0.5 0.0013 18.5 0.0 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 CEP16490.1 - 0.023 14.1 0.0 0.072 12.5 0.0 1.9 1 0 0 1 1 1 0 ACT domain DehI PF10778.4 CEP16490.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI Arrestin_N PF00339.24 CEP16491.1 - 1.5e-09 37.8 0.0 5.1e-09 36.1 0.0 1.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain PrpF PF04303.8 CEP16491.1 - 0.15 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 PrpF protein Kelch_5 PF13854.1 CEP16492.1 - 5.1e-21 74.1 0.7 0.0014 18.5 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CEP16492.1 - 3e-17 62.1 12.7 8.8e-07 28.5 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP16492.1 - 6.2e-16 58.0 10.1 0.00033 20.7 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP16492.1 - 1.2e-12 47.3 14.4 0.0023 18.0 0.2 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CEP16492.1 - 0.0061 16.0 9.6 0.23 11.0 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 CEP16492.1 - 0.019 14.7 9.2 12 5.8 0.1 4.9 5 0 0 5 5 5 0 Kelch motif LLGL PF08366.8 CEP16492.1 - 0.063 13.1 0.0 0.3 11.0 0.0 2.1 3 0 0 3 3 3 0 LLGL2 Y_phosphatase2 PF03162.8 CEP16493.1 - 2e-55 186.6 0.0 2.4e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CEP16493.1 - 4.7e-07 30.2 0.0 1.9e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CEP16493.1 - 0.0018 17.8 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP16493.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Prok-RING_4 PF14447.1 CEP16493.1 - 0.11 12.0 0.7 0.27 10.7 0.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DAGK_acc PF00609.14 CEP16494.1 - 1.1e-13 51.6 0.0 2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CEP16494.1 - 1.2e-13 50.6 0.0 1.2e-11 44.1 0.0 2.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain WD40 PF00400.27 CEP16495.1 - 5.4e-35 118.0 2.7 4.2e-09 35.9 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CEP16495.1 - 0.002 17.8 2.0 0.12 12.0 0.1 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CEP16495.1 - 0.019 13.8 0.4 1.1 7.9 0.0 2.6 1 1 2 3 3 3 0 Coatomer WD associated region Bacteriocin_IIi PF11758.3 CEP16495.1 - 0.022 14.3 0.3 0.048 13.2 0.2 1.5 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin Ribosomal_S19 PF00203.16 CEP16496.1 - 6.6e-33 112.1 0.4 8.9e-33 111.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 CEP16496.1 - 0.055 13.3 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH NUDIX PF00293.23 CEP16497.1 - 3.3e-17 62.4 0.1 4.5e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain p450 PF00067.17 CEP16498.1 - 2.4e-12 46.1 0.0 4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 HTH_29 PF13551.1 CEP16500.1 - 2.6e-06 27.5 0.0 1.2e-05 25.4 0.0 1.8 1 1 1 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP16500.1 - 5.9e-06 26.9 0.1 0.0024 18.6 0.0 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.1 CEP16500.1 - 8.4e-05 22.0 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP16500.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 CEP16500.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 PAX PF00292.13 CEP16500.1 - 0.0039 16.8 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain CENP-B_N PF04218.8 CEP16500.1 - 0.0068 15.8 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 CEP16500.1 - 0.0077 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain FeoC PF09012.5 CEP16500.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_Crp_2 PF13545.1 CEP16500.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_Tnp_IS630 PF01710.11 CEP16500.1 - 0.047 13.3 1.4 0.064 12.9 1.0 1.2 1 0 0 1 1 1 0 Transposase Bot1p PF12298.3 CEP16500.1 - 0.066 13.1 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein G6PD_C PF02781.11 CEP16500.1 - 0.074 11.8 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain SWIRM PF04433.12 CEP16501.1 - 8e-15 54.7 0.0 2.2e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CEP16501.1 - 7.4e-08 32.3 0.0 1.9e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP16501.1 - 1.2e-07 31.6 0.1 4.8e-07 29.7 0.1 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 CEP16501.1 - 7.8e-06 25.3 3.2 1.5e-05 24.4 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SlyX PF04102.7 CEP16501.1 - 0.0047 17.2 4.3 0.011 16.0 0.0 3.0 2 0 0 2 2 2 1 SlyX PPTA PF01239.17 CEP16502.1 - 1.6e-11 42.9 20.8 1.8e-05 23.8 0.7 5.3 5 1 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat PsiB PF06290.6 CEP16502.1 - 0.087 12.2 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Plasmid SOS inhibition protein (PsiB) MFS_1 PF07690.11 CEP16503.1 - 1.3e-30 106.3 52.0 1.6e-30 106.0 30.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily PIRT PF15099.1 CEP16503.1 - 0.071 12.3 0.2 0.19 10.9 0.1 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Kelch_4 PF13418.1 CEP16504.1 - 1.1e-15 57.1 16.0 7.4e-06 25.6 0.1 6.4 7 1 1 8 8 8 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP16504.1 - 1.6e-10 40.8 12.4 0.0015 18.6 0.1 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP16504.1 - 1.4e-07 30.9 2.6 0.086 12.6 0.0 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 CEP16504.1 - 5.8e-07 29.3 0.1 0.0007 19.4 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CEP16504.1 - 8e-07 28.9 18.9 0.2 11.8 0.3 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CEP16504.1 - 0.0014 18.1 8.0 1.4 8.5 0.0 5.6 5 1 0 5 5 5 2 Kelch motif Adeno_E3_CR2 PF02439.10 CEP16504.1 - 0.0025 17.3 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 tRNA-synt_1 PF00133.17 CEP16505.1 - 8.8e-38 129.6 0.5 1e-26 93.1 0.2 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CEP16505.1 - 2.9e-19 69.0 0.4 2.6e-11 42.7 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CEP16505.1 - 2.5e-12 46.8 0.3 5.2e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CEP16505.1 - 6.4e-08 32.0 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1690 PF07956.6 CEP16506.1 - 6e-12 45.7 6.2 8.1e-12 45.3 4.3 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Abi_2 PF07751.6 CEP16506.1 - 0.0059 16.8 1.1 0.0072 16.5 0.8 1.2 1 0 0 1 1 1 1 Abi-like protein AP-5_subunit_s1 PF15001.1 CEP16506.1 - 0.0083 16.0 2.2 0.011 15.6 1.5 1.2 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 CHCH PF06747.8 CEP16506.1 - 0.047 13.6 0.3 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 CHCH domain DUF883 PF05957.8 CEP16506.1 - 0.43 10.9 4.8 0.44 10.9 2.5 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MIT PF04212.13 CEP16506.1 - 1.5 8.7 4.9 0.62 9.9 0.9 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Ribosomal_L31e PF01198.14 CEP16507.1 - 1.3e-32 111.2 3.4 1.7e-32 110.9 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e zf-C2H2 PF00096.21 CEP16508.1 - 1.5e-15 56.4 51.0 0.00023 21.2 3.3 6.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP16508.1 - 2.2e-11 43.2 47.0 0.00045 20.3 2.9 6.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP16508.1 - 1.4e-09 37.7 39.8 2.6e-05 24.3 2.6 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEP16508.1 - 0.02 14.7 0.7 0.02 14.7 0.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Ogr_Delta PF04606.7 CEP16508.1 - 7.8 6.2 12.6 6.7 6.4 0.1 4.3 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger CDP-OH_P_transf PF01066.16 CEP16509.1 - 1.7e-11 44.2 9.4 1.7e-11 44.2 6.5 3.3 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CNH PF00780.17 CEP16510.1 - 3.5e-60 203.7 0.0 6.5e-60 202.8 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEP16510.1 - 6.2e-36 123.9 1.4 1e-35 123.2 0.4 1.8 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 CEP16510.1 - 1.5e-31 109.1 0.3 4.6e-31 107.5 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 CEP16510.1 - 1.1e-10 41.1 0.0 2.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 CEP16510.1 - 0.00064 19.8 0.1 0.0021 18.2 0.1 2.0 1 0 0 1 1 1 1 PH domain Protocadherin PF08374.6 CEP16510.1 - 0.0097 15.5 2.3 0.011 15.4 0.4 1.9 2 0 0 2 2 2 1 Protocadherin TSNR_N PF04705.7 CEP16510.1 - 0.019 14.7 0.3 0.16 11.7 0.0 2.6 3 0 0 3 3 3 0 Thiostrepton-resistance methylase, N terminus TMEM71 PF15121.1 CEP16511.1 - 0.034 13.8 0.4 0.057 13.1 0.3 1.5 1 0 0 1 1 1 0 TMEM71 protein family RNA_pol_Rpb4 PF03874.11 CEP16513.1 - 4.3 7.3 10.7 21 5.1 6.8 2.6 1 1 0 1 1 1 0 RNA polymerase Rpb4 PPR_2 PF13041.1 CEP16514.1 - 1.4e-60 201.0 37.3 7.6e-10 38.6 0.1 15.5 9 3 9 18 18 18 12 PPR repeat family PPR_3 PF13812.1 CEP16514.1 - 6.3e-55 178.8 15.3 0.0002 21.3 0.0 18.4 21 0 0 21 21 21 11 Pentatricopeptide repeat domain PPR PF01535.15 CEP16514.1 - 1.1e-41 137.8 43.5 0.00099 18.9 0.0 19.2 21 1 0 21 21 21 12 PPR repeat PPR_1 PF12854.2 CEP16514.1 - 4.1e-33 112.5 6.9 0.001 18.5 0.0 12.7 13 0 0 13 13 13 8 PPR repeat TPR_14 PF13428.1 CEP16514.1 - 9.8e-07 28.8 0.1 14 6.6 0.0 8.4 10 1 1 11 11 11 1 Tetratricopeptide repeat COX5A PF02284.11 CEP16514.1 - 0.026 14.4 0.1 0.097 12.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va TPR_16 PF13432.1 CEP16514.1 - 0.037 14.7 0.2 7.3 7.4 0.0 4.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP16514.1 - 0.04 13.7 0.5 35 4.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Bmp PF02608.9 CEP16515.1 - 0.01 14.5 0.6 0.012 14.3 0.4 1.0 1 0 0 1 1 1 0 Basic membrane protein Cupin_4 PF08007.7 CEP16516.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein Pkinase PF00069.20 CEP16517.1 - 6e-63 212.4 0.0 1e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16517.1 - 1.9e-29 102.5 0.0 3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CEP16517.1 - 1.6e-09 38.1 2.6 4.7e-09 36.6 0.4 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain PX PF00787.19 CEP16517.1 - 3e-06 26.9 2.6 3e-06 26.9 1.8 1.9 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.1 CEP16517.1 - 0.00013 20.9 0.0 0.00035 19.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RGS PF00615.14 CEP16517.1 - 0.0026 17.8 1.5 0.34 11.0 0.5 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kdo PF06293.9 CEP16517.1 - 0.035 13.1 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP16517.1 - 0.14 11.8 0.6 0.26 10.9 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_S8 PF00082.17 CEP16518.1 - 4.3e-56 190.1 1.8 6.2e-56 189.6 1.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CEP16518.1 - 1.2e-15 57.8 0.3 2.4e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pox_P35 PF03213.9 CEP16518.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein DDE_3 PF13358.1 CEP16519.1 - 8.9e-31 106.5 0.0 1.3e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP16519.1 - 3.7e-05 23.8 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 CEP16520.1 - 0.048 13.4 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RRM_1 PF00076.17 CEP16523.1 - 7.8e-84 275.3 4.0 3e-20 71.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16523.1 - 4.5e-53 177.1 1.3 3.6e-13 49.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16523.1 - 5.6e-41 138.1 0.5 4.5e-10 39.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CEP16523.1 - 5.7e-33 112.4 1.4 4.5e-32 109.5 1.2 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain OB_RNB PF08206.6 CEP16523.1 - 0.00011 21.6 1.9 1.3 8.5 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 CEP16523.1 - 0.00038 20.1 0.2 4.6 7.0 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 CEP16523.1 - 0.0036 17.4 0.0 2.2 8.5 0.0 3.3 3 0 0 3 3 3 1 Cobalamin biosynthesis central region ECH PF00378.15 CEP16524.1 - 2e-61 207.2 0.0 2.3e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HpcH_HpaI PF03328.9 CEP16525.1 - 4.3e-51 172.9 1.5 6.2e-51 172.4 1.1 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 CEP16525.1 - 4.6e-19 68.4 0.0 1.1e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold B12D PF06522.6 CEP16526.1 - 1.4e-18 66.3 0.0 1.7e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit LtrA PF06772.6 CEP16527.1 - 6.8e-22 77.8 12.5 6.8e-22 77.8 8.6 1.5 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Hydrolase_6 PF13344.1 CEP16528.1 - 2.1e-18 66.0 0.0 3.9e-17 62.0 0.0 2.2 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP16528.1 - 6.6e-15 54.5 0.0 3.6e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 CEP16528.1 - 8.4e-06 26.3 0.0 0.047 14.0 0.0 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP16528.1 - 0.00015 22.0 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HSA PF07529.8 CEP16529.1 - 1.4e-15 56.7 4.6 1.4e-15 56.7 3.2 5.2 7 1 1 8 8 8 1 HSA Myb_DNA-bind_6 PF13921.1 CEP16529.1 - 2.4e-07 30.7 0.4 1.2e-06 28.4 0.3 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Baculo_PEP_C PF04513.7 CEP16530.1 - 0.091 12.5 1.1 0.17 11.7 0.1 1.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IF-2B PF01008.12 CEP16530.1 - 0.27 10.1 2.7 0.5 9.2 1.9 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF1664 PF07889.7 CEP16530.1 - 2 8.2 7.3 0.76 9.5 0.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Lge1 PF11488.3 CEP16530.1 - 7.4 6.8 14.2 0.044 13.9 0.8 3.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 AATF-Che1 PF13339.1 CEP16530.1 - 8 6.6 19.2 16 5.6 6.8 2.8 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Myb_DNA-binding PF00249.26 CEP16531.1 - 3.5e-75 247.8 43.8 1.6e-12 47.2 0.6 10.2 10 0 0 10 10 10 10 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP16531.1 - 6.6e-75 247.1 35.7 2.8e-12 46.5 0.1 10.1 5 4 5 10 10 10 9 Myb-like DNA-binding domain Imm31 PF15595.1 CEP16531.1 - 0.0044 16.7 0.1 5.5 6.8 0.0 4.2 3 1 1 4 4 4 1 Immunity protein 31 Poxvirus_B22R_N PF13169.1 CEP16531.1 - 0.4 10.8 6.7 0.68 10.1 0.8 3.4 3 1 1 4 4 4 0 Poxvirus B22R protein N-terminal Rap1_C PF11626.3 CEP16531.1 - 0.88 9.4 22.7 2.5 8.0 1.1 6.0 4 3 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain 6PF2K PF01591.13 CEP16532.1 - 5.9e-71 238.0 0.0 9.1e-71 237.4 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEP16532.1 - 4.1e-23 82.2 0.0 7.9e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CEP16532.1 - 6.8e-06 26.0 0.0 1.8e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP16532.1 - 0.0071 17.1 0.1 0.059 14.1 0.0 2.4 2 1 1 3 3 3 1 AAA domain Imm3 PF14425.1 CEP16532.1 - 0.67 9.9 4.3 14 5.6 0.1 3.2 3 0 0 3 3 3 0 Immunity protein Imm3 TFIID_30kDa PF03540.8 CEP16533.1 - 9.1e-27 92.6 0.3 1.3e-26 92.1 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit RasGAP PF00616.14 CEP16534.1 - 1.9e-37 128.8 0.0 5.4e-37 127.3 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 CEP16534.1 - 9.9e-21 74.2 0.3 3e-20 72.6 0.2 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CEP16534.1 - 0.00014 21.3 0.3 0.00042 19.8 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT PF02985.17 CEP16534.1 - 0.005 16.8 3.9 3.1 8.1 0.1 4.2 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 CEP16534.1 - 0.036 14.3 0.0 5.6 7.3 0.0 4.4 4 1 0 4 4 4 0 HEAT repeats Peptidase_M13_N PF05649.8 CEP16536.1 - 1.1e-72 245.2 2.1 1.6e-72 244.7 1.4 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CEP16536.1 - 2.2e-67 226.2 0.0 3.5e-67 225.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.13 CEP16536.1 - 0.00093 18.8 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M13_N PF05649.8 CEP16537.1 - 8.8e-74 248.8 3.4 1.2e-73 248.3 2.3 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CEP16537.1 - 2.5e-69 232.5 0.0 4.4e-69 231.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.13 CEP16537.1 - 0.047 13.2 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M48 Peptidase_M13 PF01431.16 CEP16538.1 - 1.8e-64 216.7 0.0 3.2e-64 215.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 CEP16538.1 - 5.5e-62 210.0 4.4 3.1e-50 171.3 3.2 2.4 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M48 PF01435.13 CEP16538.1 - 0.026 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_C97 PF05903.9 CEP16540.1 - 5.3e-33 113.9 0.0 1e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain HSF_DNA-bind PF00447.12 CEP16540.1 - 1.7e-30 105.2 3.9 6.5e-30 103.3 2.7 2.1 1 1 0 1 1 1 1 HSF-type DNA-binding P5-ATPase PF12409.3 CEP16540.1 - 5.8 6.8 10.7 1.5 8.7 0.4 2.9 2 1 0 2 2 2 0 P5-type ATPase cation transporter Bap31 PF05529.7 CEP16541.1 - 3.5e-32 111.4 0.0 4.6e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like ETRAMP PF09716.5 CEP16541.1 - 0.12 12.3 0.2 0.22 11.5 0.2 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_M13_N PF05649.8 CEP16542.1 - 6.6e-58 196.6 2.5 2.4e-52 178.2 0.3 2.2 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.16 CEP16542.1 - 1.4e-54 184.4 0.0 3.2e-54 183.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M13 DUF1479 PF07350.7 CEP16543.1 - 0.05 12.0 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) zf-CCHC PF00098.18 CEP16546.1 - 0.0064 16.3 0.6 0.0064 16.3 0.4 2.5 3 0 0 3 3 3 1 Zinc knuckle Pap_E4 PF02711.9 CEP16546.1 - 6.5 7.6 10.9 8 7.3 0.2 3.0 2 2 1 3 3 3 0 E4 protein DDE_1 PF03184.14 CEP16547.1 - 5.8e-38 130.2 4.9 1.1e-31 109.6 1.5 3.6 2 2 0 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 CEP16547.1 - 1.7e-36 125.1 0.0 1.6e-30 105.7 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CEP16547.1 - 0.00022 20.9 0.0 0.00086 19.0 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 CEP16547.1 - 0.00092 19.1 1.0 0.0025 17.8 0.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP16547.1 - 0.011 15.8 1.1 0.031 14.4 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.1 CEP16547.1 - 0.029 14.0 0.5 0.13 11.9 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CEP16547.1 - 0.041 13.0 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MULE PF10551.4 CEP16547.1 - 0.091 12.9 0.3 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 MULE transposase domain adh_short PF00106.20 CEP16548.1 - 2.9e-13 50.0 0.0 6.4e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP16548.1 - 1.2e-05 25.2 0.1 1.7e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP16548.1 - 0.0059 16.2 0.0 0.046 13.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Y_phosphatase PF00102.22 CEP16549.1 - 3.8e-06 26.4 0.0 7.7e-05 22.1 0.0 2.6 1 1 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 CEP16549.1 - 2.4e-05 23.9 0.0 9.8e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain FCH PF00611.18 CEP16551.1 - 5.9e-13 48.8 1.9 5.9e-13 48.8 1.3 3.4 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CEP16551.1 - 1.4e-11 43.6 0.1 2.7e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP16551.1 - 4.5e-09 35.7 0.0 9.4e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP16551.1 - 2e-08 33.5 0.0 4.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AA_permease_2 PF13520.1 CEP16552.1 - 1.2e-64 218.4 49.0 1.2e-64 218.4 33.9 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP16552.1 - 1.6e-28 99.2 42.5 2.5e-28 98.6 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease DASH_Duo1 PF08651.5 CEP16553.1 - 5.1e-17 61.2 0.5 6.1e-17 60.9 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Duo1 ABC_tran_2 PF12848.2 CEP16553.1 - 0.1 12.4 0.2 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 ABC transporter HATPase_c PF02518.21 CEP16554.1 - 3e-28 97.7 0.7 7.4e-28 96.4 0.5 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEP16554.1 - 9.5e-22 77.1 0.0 1.4e-18 66.8 0.0 3.0 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 CEP16554.1 - 2.9e-19 68.8 0.3 1.7e-18 66.3 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 CEP16554.1 - 5.3e-13 49.3 0.0 2.1e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.20 CEP16554.1 - 1.9e-10 40.3 0.0 1.1e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 Protein kinase domain GAF_3 PF13492.1 CEP16554.1 - 2.5e-08 34.0 0.0 1.1e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 CEP16554.1 - 4.1e-07 30.2 0.0 9.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 CEP16554.1 - 1.7e-06 28.6 0.0 4.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain NACHT PF05729.7 CEP16554.1 - 0.0055 16.3 0.0 0.021 14.4 0.0 2.1 1 1 0 1 1 1 1 NACHT domain Kei1 PF08552.6 CEP16555.1 - 3.8e-06 26.6 3.2 5e-06 26.3 2.2 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Tmemb_161AB PF10268.4 CEP16555.1 - 0.027 13.0 0.9 0.031 12.7 0.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF2593 PF10767.4 CEP16555.1 - 0.097 12.3 1.2 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) RVT_1 PF00078.22 CEP16557.1 - 4.1e-08 32.8 0.0 4.4e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.12 CEP16557.1 - 0.13 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Euplotes_phero PF05842.6 CEP16558.1 - 0.088 13.1 2.0 0.093 13.0 0.2 1.9 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein PNPase PF03726.9 CEP16558.1 - 0.41 10.9 8.4 3.6 7.9 0.2 2.8 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain MukB PF04310.7 CEP16559.1 - 0.088 12.1 0.5 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 MukB N-terminal NUDIX PF00293.23 CEP16561.1 - 6.5e-13 48.4 0.0 8.6e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Yqai PF09466.5 CEP16562.1 - 0.096 12.7 3.1 2.9 7.9 0.1 2.4 1 1 1 2 2 2 0 Hypothetical protein Yqai Endosulfine PF04667.12 CEP16562.1 - 2.3 8.2 5.4 3.6 7.6 0.2 2.4 2 0 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region OSCP PF00213.13 CEP16563.1 - 0.059 13.2 7.6 9.1 6.1 5.3 2.4 1 1 0 1 1 1 0 ATP synthase delta (OSCP) subunit Methyltransf_8 PF05148.10 CEP16564.1 - 1.6e-79 266.6 3.6 7.3e-79 264.4 0.1 2.3 1 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CEP16564.1 - 2.5e-09 37.5 0.1 8e-09 35.8 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP16564.1 - 1.6e-05 24.5 2.6 0.0012 18.4 0.2 3.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP16564.1 - 0.0001 21.5 0.1 0.00029 20.0 0.1 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CEP16564.1 - 0.00015 21.2 0.3 0.0049 16.2 0.1 2.3 1 1 1 2 2 2 1 Methyltransferase small domain DNA_ligase_A_M PF01068.16 CEP16565.1 - 1.5e-20 73.4 0.9 2.5e-20 72.7 0.6 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Methyltransf_31 PF13847.1 CEP16565.1 - 4.2e-13 49.1 0.0 9.4e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP16565.1 - 1.9e-12 47.5 0.0 5.5e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP16565.1 - 8.7e-09 35.9 0.0 2.4e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP16565.1 - 1.6e-07 31.6 0.1 6.6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP16565.1 - 8.1e-07 29.4 0.0 2.4e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DNA_ligase_OB_2 PF14743.1 CEP16565.1 - 4.6e-06 26.2 0.0 9.7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.14 CEP16565.1 - 0.00047 19.8 0.3 0.0011 18.7 0.2 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain NodS PF05401.6 CEP16565.1 - 0.00047 19.5 0.0 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 CEP16565.1 - 0.019 14.3 0.0 0.065 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DNA_ligase_A_N PF04675.9 CEP16565.1 - 0.03 14.1 0.1 0.33 10.7 0.0 2.6 1 1 2 3 3 3 0 DNA ligase N terminus HSP70 PF00012.15 CEP16566.1 - 3.9e-106 355.3 4.6 3.9e-106 355.3 3.2 1.3 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CEP16566.1 - 4.4e-14 51.8 1.3 7.9e-14 50.9 0.6 1.6 2 0 0 2 2 2 1 MreB/Mbl protein Metallopep PF12044.3 CEP16567.1 - 3.5e-130 434.2 0.0 4.4e-130 433.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 CEP16567.1 - 5.3e-08 32.8 0.1 2.2e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Jacalin-like lectin domain Peptidase_M66 PF10462.4 CEP16567.1 - 0.021 13.6 0.3 0.035 12.9 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.1 CEP16567.1 - 0.13 12.1 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 CRAL_TRIO PF00650.15 CEP16569.1 - 2.3e-14 53.1 0.0 5.2e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP16569.1 - 0.023 14.8 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain GATA PF00320.22 CEP16570.1 - 3.9e-14 51.6 4.7 8.5e-14 50.6 3.3 1.6 1 0 0 1 1 1 1 GATA zinc finger RNA_pol_Rpc4 PF05132.9 CEP16570.1 - 0.08 12.9 1.5 0.14 12.1 1.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 TPR_14 PF13428.1 CEP16571.1 - 2.5e-12 46.2 14.7 0.029 14.9 0.0 11.1 7 4 4 11 11 11 1 Tetratricopeptide repeat Suf PF05843.9 CEP16571.1 - 4.3e-12 46.3 12.4 0.027 14.1 0.1 7.1 3 2 3 7 7 7 5 Suppressor of forked protein (Suf) TPR_11 PF13414.1 CEP16571.1 - 9.1e-11 41.2 11.0 0.29 10.7 0.0 8.8 7 2 2 9 9 9 4 TPR repeat TPR_12 PF13424.1 CEP16571.1 - 4.5e-10 39.3 10.0 0.00019 21.3 0.0 7.5 7 3 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEP16571.1 - 6.8e-09 35.9 3.6 1.4 9.2 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP16571.1 - 3.9e-07 30.5 12.7 0.012 16.2 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP16571.1 - 5e-06 26.0 24.5 0.91 9.6 0.1 10.1 11 0 0 11 11 10 2 Tetratricopeptide repeat NRDE-2 PF08424.5 CEP16571.1 - 5.1e-06 25.5 9.9 1.6e-05 23.9 0.7 4.4 2 2 1 4 4 4 1 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.7 CEP16571.1 - 0.00069 19.3 8.1 5.3 6.8 0.0 6.4 5 2 2 7 7 7 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 CEP16571.1 - 0.0024 17.5 12.3 0.013 15.2 0.0 6.3 9 0 0 9 9 8 1 Tetratricopeptide repeat CKAP2_C PF15297.1 CEP16571.1 - 0.01 14.6 0.3 0.16 10.7 0.0 2.8 3 0 0 3 3 3 0 Cytoskeleton-associated protein 2 C-terminus TPR_17 PF13431.1 CEP16571.1 - 0.026 14.7 11.8 33 5.0 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat SNAP PF14938.1 CEP16571.1 - 0.04 13.0 7.6 0.11 11.6 0.1 4.4 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP Exonuc_VII_S PF02609.11 CEP16571.1 - 0.34 10.7 3.4 1.8 8.3 0.1 3.9 4 0 0 4 4 4 0 Exonuclease VII small subunit TPR_6 PF13174.1 CEP16571.1 - 0.52 10.8 23.6 12 6.6 0.0 8.7 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP16571.1 - 1.5 8.5 16.1 63 3.4 0.1 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat SH3_1 PF00018.23 CEP16572.1 - 8e-07 28.3 0.0 1.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP16572.1 - 2.4e-05 23.8 0.0 5.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.18 CEP16572.1 - 0.0012 19.2 0.1 0.46 11.0 0.0 3.6 2 2 1 3 3 3 1 Ras association (RalGDS/AF-6) domain DUF3747 PF12565.3 CEP16572.1 - 0.036 13.1 0.0 0.089 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) Rap_GAP PF02145.10 CEP16573.1 - 0.036 13.4 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Rap/ran-GAP Senescence_reg PF04520.8 CEP16573.1 - 0.32 11.4 4.2 0.4 11.1 2.6 1.5 1 1 0 1 1 1 0 Senescence regulator Na_H_Exchanger PF00999.16 CEP16575.1 - 3.6e-60 203.4 30.8 4.4e-60 203.2 21.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4191 PF13829.1 CEP16575.1 - 5.9 5.9 8.8 1.2 8.1 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DUF2838 PF10998.3 CEP16576.1 - 9.6e-37 125.2 8.3 9.6e-37 125.2 5.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) COG5 PF10392.4 CEP16576.1 - 0.032 14.1 0.5 0.059 13.3 0.3 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2252 PF10009.4 CEP16576.1 - 0.045 12.6 0.7 0.061 12.2 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Prominin PF05478.6 CEP16576.1 - 0.057 10.9 1.3 0.081 10.4 0.9 1.1 1 0 0 1 1 1 0 Prominin DUF3487 PF11990.3 CEP16576.1 - 4.7 6.6 6.6 0.78 9.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Choline_kinase PF01633.15 CEP16577.1 - 2.2e-56 190.7 0.3 3.6e-56 190.0 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CEP16577.1 - 1.6e-07 31.3 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3961 PF13106.1 CEP16578.1 - 0.21 11.1 10.8 0.063 12.8 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) RhoGAP PF00620.22 CEP16580.1 - 1.6e-48 164.1 0.0 4.3e-48 162.7 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CEP16580.1 - 2.2e-08 34.0 8.1 2.2e-08 34.0 5.6 3.3 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 CEP16580.1 - 5.5e-08 32.4 4.6 5.5e-08 32.4 3.2 3.6 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) V_ATPase_I PF01496.14 CEP16580.1 - 2.1 6.0 9.7 4.3 5.0 6.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 CEP16581.1 - 0.00012 22.2 3.9 0.00017 21.8 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF904) COG6 PF06419.6 CEP16581.1 - 0.0039 15.3 1.3 0.0043 15.2 0.9 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Gp49 PF05973.9 CEP16581.1 - 0.0057 16.6 0.1 0.0071 16.3 0.0 1.1 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) DUF837 PF05769.6 CEP16581.1 - 0.019 14.5 2.2 0.019 14.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Cep57_CLD_2 PF14197.1 CEP16581.1 - 0.071 13.0 1.4 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4047 PF13256.1 CEP16581.1 - 0.15 12.0 1.5 0.16 11.9 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Sec2p PF06428.6 CEP16581.1 - 0.15 11.8 2.3 0.46 10.3 1.6 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF16 PF01519.11 CEP16581.1 - 0.19 11.9 2.8 0.22 11.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.3 CEP16581.1 - 0.24 11.2 8.2 0.69 9.7 2.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Syntaxin PF00804.20 CEP16581.1 - 0.24 11.5 4.1 0.26 11.4 2.9 1.1 1 0 0 1 1 1 0 Syntaxin CCDC92 PF14916.1 CEP16581.1 - 0.64 9.6 5.2 0.46 10.1 1.5 2.0 1 1 1 2 2 2 0 Coiled-coil domain of unknown function DivIC PF04977.10 CEP16581.1 - 3 7.4 7.7 5.4 6.5 1.6 2.1 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_L15e PF00827.12 CEP16582.1 - 1.5e-87 292.1 10.4 2.6e-87 291.2 7.2 1.4 1 0 0 1 1 1 1 Ribosomal L15 F-box-like PF12937.2 CEP16582.1 - 6e-10 38.6 8.7 1.2e-09 37.6 2.3 3.8 4 0 0 4 4 4 1 F-box-like LRR_6 PF13516.1 CEP16582.1 - 1.3e-08 33.9 10.6 2.4 8.4 0.0 10.0 10 0 0 10 10 10 2 Leucine Rich repeat F-box PF00646.28 CEP16582.1 - 3.6e-05 23.2 4.3 0.0002 20.8 0.2 3.7 4 0 0 4 4 4 1 F-box domain TruB_N PF01509.13 CEP16583.1 - 5.2e-44 149.9 0.0 1.2e-43 148.8 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) SpoIIIAH PF12685.2 CEP16583.1 - 0.001 18.6 1.0 0.0015 18.0 0.7 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF1469 PF07332.6 CEP16583.1 - 0.0018 18.0 0.6 0.0031 17.2 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) OSTbeta PF15048.1 CEP16583.1 - 0.0028 17.7 2.2 0.0057 16.7 1.2 1.6 1 1 0 1 1 1 1 Organic solute transporter subunit beta protein ABC_membrane PF00664.18 CEP16583.1 - 0.0033 16.8 0.2 0.0052 16.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Neur_chan_memb PF02932.11 CEP16583.1 - 0.0039 17.1 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3609 PF12259.3 CEP16583.1 - 0.0059 15.3 0.5 0.01 14.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) DUF1510 PF07423.6 CEP16583.1 - 0.0073 15.7 2.0 0.013 14.8 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) PAP_PilO PF06864.7 CEP16583.1 - 0.0079 14.5 0.2 0.011 14.0 0.2 1.2 1 0 0 1 1 1 1 Pilin accessory protein (PilO) ASFV_J13L PF05568.6 CEP16583.1 - 0.01 15.3 0.3 0.018 14.5 0.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein V_ATPase_I PF01496.14 CEP16583.1 - 0.013 13.4 0.4 0.013 13.4 0.3 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4381 PF14316.1 CEP16583.1 - 0.024 14.7 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Shisa PF13908.1 CEP16583.1 - 0.028 14.6 0.5 0.053 13.6 0.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 CEP16583.1 - 0.034 13.7 3.2 0.071 12.7 2.2 1.5 1 0 0 1 1 1 0 Rifin/stevor family AMA-1 PF02430.10 CEP16583.1 - 0.043 12.6 0.5 0.07 12.0 0.3 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 OAD_gamma PF04277.8 CEP16583.1 - 0.048 14.0 0.8 0.048 14.0 0.6 1.6 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.1 CEP16583.1 - 0.054 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 CEP16583.1 - 0.062 11.5 0.1 0.099 10.8 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CEP16583.1 - 0.066 12.9 2.7 0.13 11.9 1.8 1.6 1 1 0 1 1 1 0 TMEM154 protein family MFS_1 PF07690.11 CEP16583.1 - 0.088 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Syndecan PF01034.15 CEP16583.1 - 0.094 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Sugar_tr PF00083.19 CEP16583.1 - 0.15 10.6 0.4 0.23 9.9 0.3 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter DUF2500 PF10694.4 CEP16583.1 - 0.21 11.6 0.9 0.51 10.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Vpu PF00558.14 CEP16583.1 - 0.4 10.2 5.0 0.87 9.1 3.4 1.5 1 0 0 1 1 1 0 Vpu protein DUF4446 PF14584.1 CEP16583.1 - 0.44 10.3 5.1 0.21 11.3 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) P12 PF12669.2 CEP16583.1 - 1.7 8.8 5.3 3.6 7.8 3.7 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family Ribosomal_L34e PF01199.13 CEP16585.1 - 3.6e-41 139.2 5.8 4.5e-41 138.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e GFA PF04828.9 CEP16585.1 - 0.16 11.8 0.8 0.41 10.6 0.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 CEP16585.1 - 1.3 9.3 5.3 0.34 11.1 0.9 2.1 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Mu-like_Com PF10122.4 CEP16585.1 - 10 5.2 8.0 2.7 7.1 0.1 2.7 3 0 0 3 3 3 0 Mu-like prophage protein Com NUC153 PF08159.7 CEP16586.1 - 6.7e-12 44.7 14.2 1.9e-11 43.3 0.3 3.9 3 0 0 3 3 3 2 NUC153 domain GCR1_C PF12550.3 CEP16587.1 - 0.00065 19.5 0.7 0.00065 19.5 0.5 2.0 2 1 0 2 2 2 1 Transcriptional activator of glycolytic enzymes ParB PF08775.5 CEP16587.1 - 0.05 13.9 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 ParB family V-SNARE PF05008.10 CEP16587.1 - 0.079 13.1 0.4 0.15 12.2 0.3 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus RRM_1 PF00076.17 CEP16588.1 - 4.6e-37 125.4 0.0 7.1e-21 73.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16588.1 - 1.4e-25 89.0 0.0 1e-13 51.0 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16588.1 - 4.1e-10 39.3 0.0 1.8e-05 24.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ER PF01133.12 CEP16588.1 - 3.4e-07 29.8 0.0 9.4e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 Enhancer of rudimentary PABP PF00658.13 CEP16588.1 - 0.0036 16.9 4.6 0.026 14.2 0.0 3.5 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain SR-25 PF10500.4 CEP16588.1 - 0.17 11.3 15.2 0.26 10.7 0.8 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 CEP16588.1 - 0.86 9.6 30.9 0.88 9.6 5.7 4.3 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.7 CEP16588.1 - 0.88 9.4 11.8 1.9 8.2 0.4 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Lipase_3 PF01764.20 CEP16589.1 - 1.3e-20 73.4 0.0 2.2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FA_desaturase PF00487.19 CEP16589.1 - 0.0045 16.4 0.8 0.0045 16.4 0.5 1.9 2 0 0 2 2 2 1 Fatty acid desaturase Utp21 PF04192.7 CEP16590.1 - 1.5e-66 223.8 0.4 2.8e-66 223.0 0.3 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CEP16590.1 - 3.9e-39 131.1 12.7 1.8e-08 33.9 0.4 10.2 10 0 0 10 10 10 6 WD domain, G-beta repeat Nup160 PF11715.3 CEP16590.1 - 9.6e-09 33.9 5.9 0.039 12.1 0.2 4.2 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CEP16590.1 - 7e-05 21.7 5.8 0.024 13.3 0.4 3.5 3 2 1 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 CEP16590.1 - 0.0046 15.3 0.1 0.14 10.4 0.0 2.9 2 1 1 3 3 3 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 CEP16590.1 - 0.018 14.5 0.0 1.9 7.9 0.0 3.5 2 1 0 2 2 2 0 PQQ-like domain TCO89 PF10452.4 CEP16591.1 - 0.03 13.2 22.0 0.07 12.0 14.0 1.9 1 1 1 2 2 2 0 TORC1 subunit TCO89 Exonuc_VII_L PF02601.10 CEP16591.1 - 1.1 8.3 10.3 1.4 8.0 7.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mcm10 PF09332.6 CEP16591.1 - 2.6 7.2 15.4 3 7.1 5.1 2.1 1 1 1 2 2 2 0 Mcm10 replication factor PHD PF00628.24 CEP16592.1 - 1e-05 25.1 14.3 1e-05 25.1 9.9 1.8 2 0 0 2 2 2 1 PHD-finger GATA PF00320.22 CEP16592.1 - 5.7e-05 22.3 5.5 5.7e-05 22.3 3.8 1.8 2 0 0 2 2 2 1 GATA zinc finger zf-HC5HC2H PF13771.1 CEP16592.1 - 0.49 10.5 9.5 0.26 11.4 3.8 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain PAP_assoc PF03828.14 CEP16593.1 - 1.8e-09 37.3 0.0 6.1e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CEP16593.1 - 2.1e-06 27.9 0.0 5.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.20 CEP16594.1 - 5.4e-51 173.2 0.1 1.1e-50 172.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16594.1 - 2.6e-23 82.4 0.0 4.7e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CEP16594.1 - 0.0017 17.2 0.1 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Synaphin PF05835.7 CEP16594.1 - 0.003 17.7 6.3 0.0071 16.4 4.4 1.6 1 0 0 1 1 1 1 Synaphin protein RIO1 PF01163.17 CEP16594.1 - 0.02 14.2 0.4 0.55 9.5 0.3 2.4 1 1 0 1 1 1 0 RIO1 family Acyltransferase PF01553.16 CEP16595.1 - 2.8e-07 30.0 0.0 4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TP_methylase PF00590.15 CEP16596.1 - 2.3e-44 151.6 0.1 3.7e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 CEP16596.1 - 1.4e-17 62.7 0.1 2.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 CEP16596.1 - 1.8e-11 44.2 0.0 4.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 CEP16596.1 - 2.7e-06 26.2 0.5 4.9e-06 25.4 0.4 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central CTP_synth_N PF06418.9 CEP16597.1 - 6.2e-121 402.7 0.1 8.6e-121 402.2 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CEP16597.1 - 6.6e-59 198.5 0.0 1e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CEP16597.1 - 4.3e-07 29.5 0.0 8.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 CEP16597.1 - 0.0092 15.4 0.0 0.026 13.9 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 CEP16598.1 - 9.3e-41 139.1 0.0 1e-23 83.9 0.0 3.5 2 1 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEP16598.1 - 5.5e-13 49.3 2.0 0.0012 18.8 0.0 4.3 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CEP16598.1 - 1.5e-11 44.5 0.0 0.0017 18.4 0.0 3.6 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 CEP16598.1 - 1.9e-09 36.8 0.0 0.00059 18.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_5 PF07728.9 CEP16598.1 - 2.5e-09 36.9 0.0 0.00055 19.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CEP16598.1 - 2.7e-07 31.4 0.1 0.0049 17.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CEP16598.1 - 3.6e-07 29.4 0.3 0.024 13.7 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin IstB_IS21 PF01695.12 CEP16598.1 - 5e-07 29.3 0.0 0.0005 19.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 CEP16598.1 - 1.2e-06 28.4 0.0 0.0083 16.0 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CEP16598.1 - 2.5e-06 27.0 1.5 0.14 11.5 0.1 3.5 3 1 1 4 4 4 2 AAA domain AAA_19 PF13245.1 CEP16598.1 - 4.7e-06 26.2 1.0 0.002 17.8 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activat PF00158.21 CEP16598.1 - 6.8e-06 25.6 0.0 0.14 11.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CEP16598.1 - 7.2e-06 26.3 0.1 0.15 12.3 0.0 2.8 2 2 0 2 2 2 2 ABC transporter AAA_14 PF13173.1 CEP16598.1 - 1e-05 25.4 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CEP16598.1 - 1.3e-05 25.3 0.0 0.074 13.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Sigma54_activ_2 PF14532.1 CEP16598.1 - 1.3e-05 25.2 0.0 0.0071 16.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 CEP16598.1 - 1.7e-05 24.5 0.5 0.39 10.3 0.0 3.4 3 1 0 3 3 3 2 NACHT domain KaiC PF06745.8 CEP16598.1 - 2.5e-05 23.5 0.0 0.065 12.3 0.0 2.4 2 0 0 2 2 2 2 KaiC RuvB_N PF05496.7 CEP16598.1 - 2.6e-05 23.4 0.1 0.00022 20.3 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CEP16598.1 - 3.4e-05 23.0 0.2 0.012 14.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CEP16598.1 - 4.1e-05 23.8 0.4 0.11 12.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 CEP16598.1 - 4.6e-05 23.4 0.2 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CEP16598.1 - 5.1e-05 22.1 0.1 0.0057 15.4 0.0 2.7 3 0 0 3 3 3 1 TIP49 C-terminus AAA_2 PF07724.9 CEP16598.1 - 6.9e-05 22.8 0.0 0.16 11.8 0.0 3.3 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 CEP16598.1 - 7.9e-05 22.3 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain MCM PF00493.18 CEP16598.1 - 8.2e-05 21.5 0.0 0.02 13.7 0.0 2.3 2 0 0 2 2 2 1 MCM2/3/5 family UPF0079 PF02367.12 CEP16598.1 - 0.00024 20.7 0.2 1 9.0 0.0 3.1 4 0 0 4 4 2 2 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CEP16598.1 - 0.00028 20.1 0.2 0.05 12.8 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_29 PF13555.1 CEP16598.1 - 0.00035 20.0 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.1 CEP16598.1 - 0.0011 18.6 0.2 0.036 13.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 CEP16598.1 - 0.0029 16.6 2.8 0.74 8.7 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 CEP16598.1 - 0.0039 17.6 0.1 0.72 10.3 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein Bac_DnaA PF00308.13 CEP16598.1 - 0.0067 16.0 0.1 5.8 6.4 0.0 2.9 2 1 0 2 2 2 0 Bacterial dnaA protein ATP-synt_ab PF00006.20 CEP16598.1 - 0.0068 15.9 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 CEP16598.1 - 0.0074 15.4 0.1 0.26 10.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NB-ARC PF00931.17 CEP16598.1 - 0.012 14.5 0.1 0.5 9.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.6 CEP16598.1 - 0.014 14.9 0.0 0.23 11.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CEP16598.1 - 0.015 14.7 0.2 5.9 6.2 0.0 3.2 3 1 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 CEP16598.1 - 0.015 15.6 0.4 5.4 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain Torsin PF06309.6 CEP16598.1 - 0.018 14.9 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 0 Torsin Arch_ATPase PF01637.13 CEP16598.1 - 0.019 14.6 0.0 2 8.0 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 CEP16598.1 - 0.022 13.6 1.0 2.8 6.7 0.0 3.3 3 1 0 3 3 2 0 Type II/IV secretion system protein DAP3 PF10236.4 CEP16598.1 - 0.028 13.3 0.0 2.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Guanylate_kin PF00625.16 CEP16598.1 - 0.037 13.4 0.1 1.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Guanylate kinase MobB PF03205.9 CEP16598.1 - 0.044 13.4 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 CEP16598.1 - 0.046 12.6 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Parvo_NS1 PF01057.12 CEP16598.1 - 0.051 12.4 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CPT PF07931.7 CEP16598.1 - 0.088 12.4 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 CEP16598.1 - 0.094 12.2 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 CEP16598.1 - 0.22 10.9 1.2 71 2.7 0.0 3.7 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) Pro-NT_NN PF07421.6 CEP16599.1 - 0.015 14.8 0.3 0.049 13.1 0.2 1.8 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor DUF148 PF02520.12 CEP16599.1 - 8 6.2 17.0 1.8 8.4 1.4 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF148 F-box-like PF12937.2 CEP16600.1 - 2.8e-08 33.3 0.2 9.9e-08 31.5 0.0 2.1 3 0 0 3 3 3 1 F-box-like DDE_3 PF13358.1 CEP16601.1 - 1.9e-31 108.8 0.0 7.3e-31 106.8 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP16601.1 - 0.00032 20.6 0.3 0.00085 19.2 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain rve PF00665.21 CEP16601.1 - 0.0081 16.2 0.0 0.035 14.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 CEP16601.1 - 0.0094 15.5 0.1 0.026 14.1 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP16601.1 - 0.0096 16.0 1.2 0.04 14.0 0.3 2.5 3 1 0 3 3 3 1 Winged helix-turn helix Chitin_synth_1 PF01644.12 CEP16602.1 - 7e-73 243.7 0.2 1.4e-72 242.7 0.2 1.5 1 1 0 1 1 1 1 Chitin synthase SNAP PF14938.1 CEP16602.1 - 1e-29 103.6 12.0 1.6e-29 102.9 8.3 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Chitin_synth_1N PF08407.6 CEP16602.1 - 1.5e-28 98.3 0.1 3.7e-28 97.0 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEP16602.1 - 1.1e-25 90.0 0.1 8.9e-20 70.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP16602.1 - 1.7e-07 31.1 0.1 1.7e-07 31.1 0.1 2.4 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP16602.1 - 3.8e-06 26.8 0.0 1.2e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase like family 2 TPR_14 PF13428.1 CEP16602.1 - 0.037 14.6 0.2 11 6.9 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP16602.1 - 0.14 11.7 17.3 0.22 11.1 2.1 4.3 2 1 2 4 4 4 0 TPR repeat TPR_16 PF13432.1 CEP16602.1 - 0.8 10.4 7.9 4.4 8.0 2.4 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP16602.1 - 1 9.3 9.6 2.1 8.3 0.8 3.7 1 1 1 3 3 3 0 Tetratricopeptide repeat ARD PF03079.9 CEP16605.1 - 7.6e-51 172.1 1.4 8.8e-51 171.9 1.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CEP16605.1 - 5.7e-09 35.3 0.0 9.3e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CEP16605.1 - 5.7e-06 26.0 0.0 8.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 CEP16605.1 - 0.0078 15.6 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Cupin EF-hand_1 PF00036.27 CEP16606.1 - 7.2e-41 134.3 10.7 2.8e-10 38.7 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEP16606.1 - 4.5e-36 122.8 4.4 1.2e-20 73.3 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CEP16606.1 - 3.7e-32 109.6 12.0 5.6e-16 57.8 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CEP16606.1 - 2.4e-30 101.6 5.5 2.7e-09 36.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CEP16606.1 - 1.2e-24 84.4 6.6 1.2e-06 27.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CEP16606.1 - 5.9e-13 48.5 0.1 8.2e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CEP16606.1 - 1.7e-10 40.9 0.0 2.1e-05 24.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEP16606.1 - 1.2e-08 34.6 1.3 0.00084 19.0 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 CEP16606.1 - 3.9e-06 26.7 0.7 3.9e-06 26.7 0.5 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 CEP16606.1 - 8.6e-05 22.0 1.3 0.0059 16.2 0.0 3.3 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) DUF1103 PF06513.6 CEP16606.1 - 0.00039 19.8 0.8 0.00047 19.6 0.6 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 CEP16606.1 - 0.00044 19.9 1.0 0.26 11.0 0.0 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB EF-hand_like PF09279.6 CEP16606.1 - 0.00062 19.7 2.0 0.0052 16.7 0.2 2.6 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 CEP16606.1 - 0.024 14.6 3.7 0.72 9.8 0.2 2.7 3 1 0 3 3 3 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 CEP16606.1 - 0.031 13.8 0.4 0.99 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF2267 PF10025.4 CEP16606.1 - 0.064 13.3 0.0 0.7 9.9 0.0 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF853 PF05872.7 CEP16606.1 - 0.068 11.5 0.0 0.17 10.2 0.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Caleosin PF05042.8 CEP16606.1 - 0.081 12.4 0.0 8.3 5.9 0.0 2.5 1 1 0 2 2 2 0 Caleosin related protein Fe_hyd_lg_C PF02906.9 CEP16606.1 - 0.092 11.9 0.9 0.15 11.2 0.6 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF3650 PF12368.3 CEP16606.1 - 0.61 9.6 3.8 45 3.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) DUF3018 PF11455.3 CEP16606.1 - 0.7 9.8 4.3 10 6.1 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3018) TRAM_LAG1_CLN8 PF03798.11 CEP16608.1 - 4.8e-39 133.9 26.9 4.8e-39 133.9 18.7 1.8 2 0 0 2 2 2 1 TLC domain RVT_1 PF00078.22 CEP16609.1 - 3e-13 49.6 0.0 5.1e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 CEP16610.1 - 1.4e-10 40.8 59.4 0.00031 20.8 1.0 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP16610.1 - 5.5e-09 35.8 15.1 2e-06 27.7 2.3 6.2 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP16610.1 - 0.00059 19.9 35.1 0.0095 16.2 2.1 5.9 6 0 0 6 6 6 4 C2H2-type zinc finger Ogr_Delta PF04606.7 CEP16610.1 - 0.17 11.5 2.7 16 5.2 0.0 3.5 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger GSH_synth_ATP PF03917.12 CEP16611.1 - 3.9e-119 397.5 0.0 4.7e-119 397.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CEP16611.1 - 6.7e-36 122.5 0.0 1.3e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase LOH1CR12 PF10158.4 CEP16611.1 - 0.034 13.9 0.4 0.073 12.8 0.3 1.5 1 0 0 1 1 1 0 Tumour suppressor protein DUF3877 PF12993.2 CEP16611.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF1212 PF06738.7 CEP16612.1 - 2.2e-35 121.9 14.3 9.9e-34 116.4 0.3 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CEP16612.1 - 1.9e-10 40.7 8.8 1.9e-10 40.7 6.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) B-block_TFIIIC PF04182.7 CEP16613.1 - 3.6e-16 58.7 1.8 1.3e-15 56.9 0.2 2.8 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC HTH_24 PF13412.1 CEP16613.1 - 4.1e-05 22.8 0.1 0.00038 19.7 0.0 2.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 CEP16613.1 - 0.00042 19.9 0.0 0.0034 17.0 0.0 2.6 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 CEP16613.1 - 0.001 19.3 0.1 0.0073 16.5 0.0 2.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.17 CEP16613.1 - 0.0019 17.8 0.9 0.014 15.1 0.0 3.0 3 0 0 3 3 3 1 MarR family RNA_pol_Rpb2_5 PF04567.12 CEP16613.1 - 0.041 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 RPA_C PF08784.6 CEP16613.1 - 0.061 13.7 0.1 1.2 9.5 0.0 2.9 2 0 0 2 2 2 0 Replication protein A C terminal polyprenyl_synt PF00348.12 CEP16614.1 - 1.2e-35 122.5 0.0 4.1e-35 120.8 0.0 1.8 1 1 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.14 CEP16614.1 - 0.00029 20.1 0.0 0.001 18.4 0.0 1.7 1 1 0 1 1 1 1 Squalene/phytoene synthase HEPPP_synt_1 PF07307.6 CEP16614.1 - 0.017 14.5 0.1 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DDE_Tnp_1_7 PF13843.1 CEP16615.1 - 3.2e-09 36.3 0.0 7.1e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 Transposase IS4 Orbi_VP3 PF01700.11 CEP16615.1 - 0.072 10.5 0.0 0.099 10.0 0.0 1.2 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein ERp29 PF07749.7 CEP16616.1 - 0.00036 21.1 0.4 0.00076 20.0 0.3 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Polyhedrin PF00738.13 CEP16616.1 - 0.14 11.2 0.5 0.21 10.6 0.3 1.4 1 1 0 1 1 1 0 Polyhedrin DUF500 PF04366.7 CEP16617.1 - 5.1e-32 109.9 0.9 7.7e-32 109.3 0.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CEP16617.1 - 5.3e-14 51.3 0.1 1.1e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP16617.1 - 1.2e-12 47.2 0.1 2.1e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP16617.1 - 1e-09 37.6 0.0 1.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Enkurin PF13864.1 CEP16618.1 - 2.5e-07 30.7 1.2 2.5e-07 30.7 0.8 5.5 2 1 4 6 6 6 1 Calmodulin-binding DUF869 PF05911.6 CEP16618.1 - 0.0041 15.4 45.4 0.0019 16.5 28.2 2.1 2 0 0 2 2 2 1 Plant protein of unknown function (DUF869) FlaC_arch PF05377.6 CEP16618.1 - 2 8.3 12.6 38 4.2 1.2 5.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Ribosomal_L13 PF00572.13 CEP16619.1 - 2.9e-25 88.7 0.1 5.2e-25 87.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 MobA_MobL PF03389.10 CEP16620.1 - 0.097 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 MobA/MobL family MFS_1 PF07690.11 CEP16621.1 - 6.5e-35 120.4 33.1 2.1e-34 118.7 23.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.3 CEP16621.1 - 0.062 12.4 1.5 11 5.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) UNC-93 PF05978.11 CEP16621.1 - 7.6 6.0 12.9 0.33 10.4 4.8 1.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Vps35 PF03635.12 CEP16622.1 - 0 1065.8 8.3 0 1065.6 5.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 BUD22 PF09073.5 CEP16622.1 - 0.92 8.5 26.3 1.5 7.8 18.3 1.2 1 0 0 1 1 1 0 BUD22 Borrelia_P83 PF05262.6 CEP16622.1 - 10 4.2 24.5 16 3.6 17.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein VWA_2 PF13519.1 CEP16623.1 - 3.3e-14 53.3 1.4 5.1e-14 52.7 0.0 1.9 2 1 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 CEP16623.1 - 7e-12 43.8 21.4 0.00012 21.3 0.7 4.9 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.9 CEP16623.1 - 2e-08 34.0 0.9 6.1e-08 32.4 0.0 2.1 2 1 1 3 3 3 1 Ssl1-like zf-H2C2 PF09337.5 CEP16624.1 - 0.033 13.5 1.1 0.033 13.5 0.8 1.8 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger PIF1 PF05970.9 CEP16628.1 - 4.9e-05 22.4 0.1 6.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP16628.1 - 0.00026 20.6 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CEP16628.1 - 0.00047 20.4 0.0 0.00095 19.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter PhoH PF02562.11 CEP16628.1 - 0.0026 16.9 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_17 PF13207.1 CEP16628.1 - 0.0039 18.0 0.1 0.029 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP16628.1 - 0.0073 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP16628.1 - 0.015 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 CEP16628.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 CEP16628.1 - 0.027 13.6 0.3 0.072 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CEP16628.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEP16628.1 - 0.054 13.4 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CEP16628.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Secretin_N_2 PF07655.8 CEP16629.1 - 0.1 12.9 4.5 0.16 12.4 3.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Malectin PF11721.3 CEP16630.1 - 0.025 14.3 1.0 3.9 7.2 0.1 2.5 3 0 0 3 3 3 0 Di-glucose binding within endoplasmic reticulum Pyr_redox_2 PF07992.9 CEP16631.1 - 0.0078 16.1 0.1 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Remorin_N PF03766.8 CEP16632.1 - 2.4 8.0 5.3 1 9.1 0.9 2.1 1 1 1 2 2 2 0 Remorin, N-terminal region Transposase_21 PF02992.9 CEP16636.1 - 0.045 12.8 0.1 0.045 12.8 0.1 1.8 2 0 0 2 2 2 0 Transposase family tnp2 SKIP_SNW PF02731.10 CEP16637.1 - 1.8e-64 215.9 2.3 1.8e-64 215.9 1.6 2.4 2 0 0 2 2 2 1 SKIP/SNW domain ROKNT PF08067.6 CEP16637.1 - 6.2 6.7 11.5 11 5.9 1.3 2.7 2 0 0 2 2 2 0 ROKNT (NUC014) domain DIE2_ALG10 PF04922.7 CEP16638.1 - 9.7e-52 176.2 13.3 1.2e-51 175.9 9.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family KH_1 PF00013.24 CEP16639.1 - 2.5e-67 222.3 17.0 5.7e-10 38.7 1.5 9.3 9 0 0 9 9 9 8 KH domain KH_3 PF13014.1 CEP16639.1 - 6.2e-49 162.9 18.9 3.4e-09 36.1 0.0 9.8 10 0 0 10 10 10 7 KH domain SLS PF14611.1 CEP16639.1 - 1.7e-06 27.6 9.5 1.8 7.9 0.0 5.8 3 1 1 5 5 5 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 CEP16639.1 - 1.8e-06 27.4 10.5 0.87 9.1 3.0 6.1 6 1 0 6 6 6 3 KH domain PhoPQ_related PF10142.4 CEP16639.1 - 0.00083 17.9 0.4 0.02 13.3 0.0 2.4 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein zf-H2C2 PF09337.5 CEP16640.1 - 0.0017 17.7 0.1 0.0029 16.9 0.1 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger MGC-24 PF05283.6 CEP16640.1 - 0.011 15.5 1.6 0.011 15.5 1.1 2.0 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) PAPS_reduct PF01507.14 CEP16641.1 - 3.4e-29 101.8 0.0 8.1e-21 74.6 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Lipase_GDSL_2 PF13472.1 CEP16641.1 - 0.0053 16.9 0.1 0.17 11.9 0.0 3.2 4 1 0 4 4 4 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CEP16641.1 - 0.0063 16.3 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-RING_2 PF13639.1 CEP16642.1 - 4.2e-13 48.9 7.1 8.3e-13 47.9 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP16642.1 - 4.8e-09 36.1 7.4 1e-08 35.0 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP16642.1 - 8.9e-09 34.8 5.8 1.7e-08 33.9 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP16642.1 - 3.7e-07 29.7 5.1 6.6e-07 28.9 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP16642.1 - 7.6e-06 25.5 7.7 1.4e-05 24.6 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEP16642.1 - 8.4e-05 22.6 5.4 0.00019 21.4 3.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CEP16642.1 - 0.0068 16.2 7.2 0.015 15.1 5.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP16642.1 - 0.0091 15.6 1.3 0.015 14.9 0.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CEP16642.1 - 0.037 13.8 4.9 0.085 12.7 3.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2808 PF10989.3 CEP16642.1 - 0.059 12.9 0.3 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) zf-RING_4 PF14570.1 CEP16642.1 - 0.57 9.8 11.7 1.3 8.6 8.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 CEP16643.1 - 4.5e-14 52.0 7.7 7.2e-14 51.3 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 CEP16643.1 - 1.7e-06 27.6 0.1 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.20 CEP16643.1 - 1.8e-06 27.5 5.7 3.1e-06 26.7 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP16643.1 - 3.2e-06 27.0 7.8 5.4e-06 26.3 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEP16643.1 - 2.6e-05 24.2 4.8 7e-05 22.8 3.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CEP16643.1 - 0.0013 18.3 6.5 0.0022 17.6 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CEP16643.1 - 0.0049 16.6 2.6 0.009 15.8 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CEP16643.1 - 0.0051 16.4 6.3 0.0082 15.7 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Shisa PF13908.1 CEP16643.1 - 0.018 15.2 0.1 0.059 13.5 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ly49 PF08391.5 CEP16643.1 - 0.026 14.6 0.2 0.06 13.4 0.2 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Prok-RING_1 PF14446.1 CEP16643.1 - 0.027 14.2 5.7 0.055 13.2 3.9 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Nse PF11789.3 CEP16643.1 - 0.05 13.1 2.0 0.1 12.1 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1774 PF08611.5 CEP16643.1 - 0.21 11.7 1.3 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) FANCL_C PF11793.3 CEP16643.1 - 2.5 8.1 6.3 26 4.8 4.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 CEP16643.1 - 2.6 8.0 7.2 5.3 6.9 5.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CEP16643.1 - 5 6.7 6.7 8.8 6.0 4.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RecO_N_2 PF13114.1 CEP16645.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 RecO N terminal DEC-1_N PF04625.8 CEP16645.1 - 0.036 12.7 8.5 0.039 12.6 5.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FAP PF07174.6 CEP16645.1 - 0.54 9.5 14.3 0.63 9.2 9.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ADH_N PF08240.7 CEP16649.1 - 4.2e-26 90.8 4.0 9.7e-26 89.6 2.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP16649.1 - 2.2e-18 66.0 0.1 4.4e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PAT1 PF09770.4 CEP16650.1 - 3.9 5.5 8.7 4.5 5.3 6.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PPV_E2_N PF00508.12 CEP16651.1 - 0.21 10.7 1.3 9.5 5.3 0.1 2.0 2 0 0 2 2 2 0 E2 (early) protein, N terminal Scs3p PF10261.4 CEP16652.1 - 5.6e-53 179.4 17.0 1.2e-52 178.3 11.8 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3270 PF11674.3 CEP16652.1 - 0.063 13.2 0.5 0.063 13.2 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) UCH PF00443.24 CEP16653.1 - 2.2e-32 112.2 1.3 5.2e-32 111.0 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CEP16653.1 - 3.5e-26 91.0 21.1 9.7e-20 70.4 2.0 3.6 5 0 0 5 5 5 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CEP16653.1 - 7.5e-20 70.1 0.3 1.2e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 CEP16653.1 - 7.7e-16 58.3 1.0 3.1e-15 56.3 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase 4HBT_3 PF13622.1 CEP16654.1 - 4.2e-40 138.0 0.1 6.5e-40 137.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CEP16654.1 - 5.5e-33 113.4 0.1 4.6e-27 94.2 0.0 3.4 2 1 0 2 2 2 2 Acyl-CoA thioesterase Tau95 PF09734.4 CEP16655.1 - 7e-60 202.9 0.4 1.2e-59 202.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Laminin_II PF06009.7 CEP16655.1 - 0.00088 19.0 0.8 0.0025 17.5 0.6 1.7 1 0 0 1 1 1 1 Laminin Domain II GldM_N PF12081.3 CEP16655.1 - 0.11 11.9 3.0 0.23 10.9 2.1 1.4 1 0 0 1 1 1 0 GldM N-terminal domain SNARE_assoc PF09335.6 CEP16656.1 - 3e-19 69.4 5.0 3e-19 69.4 3.5 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein cwf18 PF08315.7 CEP16657.1 - 1.6e-14 54.5 19.6 1.6e-14 54.5 13.6 2.3 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor CAS_CSE1 PF03378.10 CEP16657.1 - 0.12 10.6 0.3 0.13 10.5 0.2 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Ribosomal_L39 PF00832.15 CEP16657.1 - 0.3 10.5 0.1 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L39 protein DnaG_DnaB_bind PF08278.6 CEP16657.1 - 0.36 11.0 4.0 0.74 10.0 2.8 1.6 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding PAS PF00989.19 CEP16659.1 - 2.5e-15 56.2 0.3 4.2e-09 36.1 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.1 CEP16659.1 - 2.8e-10 40.4 0.2 1.1e-05 25.7 0.0 2.6 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 CEP16659.1 - 1.9e-09 37.5 0.0 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 CEP16659.1 - 2.2e-08 34.0 0.2 6e-08 32.6 0.1 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 CEP16659.1 - 2.9e-08 33.6 0.0 7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain Phosphoprotein PF00922.12 CEP16660.1 - 0.073 12.2 1.0 0.081 12.1 0.7 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Pyocin_S PF06958.7 CEP16660.1 - 0.1 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 S-type Pyocin DUF3301 PF11743.3 CEP16662.1 - 0.0025 17.2 0.2 0.0078 15.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3301) SURF4 PF02077.10 CEP16663.1 - 5.7e-94 314.4 8.8 6.5e-94 314.2 6.1 1.0 1 0 0 1 1 1 1 SURF4 family Aldose_epim PF01263.15 CEP16664.1 - 6e-44 150.3 0.4 6.7e-44 150.1 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4554 PF15091.1 CEP16664.1 - 0.087 11.5 0.2 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) LepA_C PF06421.7 CEP16666.1 - 1.1e-45 153.9 1.3 3e-45 152.5 0.9 1.8 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 CEP16666.1 - 5.7e-41 140.0 0.1 8.6e-41 139.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CEP16666.1 - 7.4e-21 73.8 0.0 1.6e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CEP16666.1 - 5.5e-06 26.3 0.1 1.2e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CEP16666.1 - 1.7e-05 24.5 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II TMEM151 PF14857.1 CEP16666.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 TMEM151 family AAA_2 PF07724.9 CEP16667.1 - 1.6e-53 181.1 4.0 3.5e-52 176.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CEP16667.1 - 1.4e-23 83.5 1.2 2.4e-12 47.1 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CEP16667.1 - 1.8e-23 82.2 1.5 3.3e-23 81.3 0.0 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CEP16667.1 - 3.3e-16 59.2 0.1 1.7e-10 40.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP16667.1 - 4.7e-11 43.0 4.0 0.0011 18.9 0.0 4.9 5 2 1 6 6 4 3 AAA ATPase domain AAA_22 PF13401.1 CEP16667.1 - 1.5e-10 41.3 2.7 0.0026 17.8 0.0 4.1 2 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CEP16667.1 - 5.8e-10 38.8 0.3 2.7e-06 26.9 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 CEP16667.1 - 1.5e-06 27.7 0.0 0.012 14.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CEP16667.1 - 2.1e-06 27.0 0.2 0.047 12.8 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CEP16667.1 - 8.3e-06 25.7 0.6 0.092 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CEP16667.1 - 4.6e-05 23.7 2.5 0.34 11.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CEP16667.1 - 5.1e-05 24.0 7.8 0.017 15.9 0.0 4.3 3 2 1 4 4 4 2 AAA domain DNA_pol3_delta2 PF13177.1 CEP16667.1 - 7.4e-05 22.4 0.4 0.071 12.7 0.0 4.0 3 1 0 3 3 3 1 DNA polymerase III, delta subunit RNA_helicase PF00910.17 CEP16667.1 - 0.00013 22.1 0.0 0.71 10.0 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_24 PF13479.1 CEP16667.1 - 0.00013 21.6 0.0 0.0096 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CEP16667.1 - 0.00048 19.8 0.3 0.18 11.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.1 CEP16667.1 - 0.00066 19.3 0.9 0.48 10.2 0.1 3.5 3 0 0 3 3 3 1 Part of AAA domain MobB PF03205.9 CEP16667.1 - 0.00085 19.0 0.0 0.26 11.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CEP16667.1 - 0.002 17.0 0.1 0.055 12.3 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 CEP16667.1 - 0.0063 15.7 0.0 3.3 6.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 CEP16667.1 - 0.0065 16.0 0.0 3.3 7.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 CEP16667.1 - 0.014 15.7 5.3 0.18 12.1 0.0 3.6 3 1 0 3 3 2 0 ABC transporter AAA_23 PF13476.1 CEP16667.1 - 0.017 15.4 10.7 13 6.0 5.6 3.8 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 CEP16667.1 - 0.022 14.2 0.2 2.8 7.3 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 CEP16667.1 - 0.033 14.1 2.4 21 5.0 0.0 4.0 4 1 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.12 CEP16667.1 - 0.035 13.6 0.1 1.4 8.3 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CEP16667.1 - 0.061 12.8 0.0 3.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4368 PF14287.1 CEP16667.1 - 0.067 13.0 1.3 0.4 10.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) AAA_29 PF13555.1 CEP16667.1 - 0.11 12.0 0.0 16 5.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 CEP16667.1 - 0.11 12.9 0.9 1.3 9.5 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein APG6 PF04111.7 CEP16667.1 - 1 8.3 9.4 2.1 7.2 6.5 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_30 PF13604.1 CEP16667.1 - 1.3 8.5 6.7 2.2 7.7 0.1 3.5 3 1 0 3 3 3 0 AAA domain Atg14 PF10186.4 CEP16667.1 - 1.9 7.3 8.7 3.6 6.4 6.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UCH PF00443.24 CEP16668.1 - 2.1e-49 168.0 2.3 2.9e-49 167.6 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP16668.1 - 1.8e-22 80.1 4.5 2.3e-22 79.7 2.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CEP16668.1 - 0.003 16.8 1.7 0.003 16.8 1.1 2.2 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase eIF3g PF12353.3 CEP16669.1 - 3.6e-36 123.8 1.9 6.5e-36 123.0 1.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CEP16669.1 - 9.6e-18 63.5 0.1 2.8e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16669.1 - 2.5e-11 43.3 0.0 7.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16669.1 - 1.4e-05 24.8 0.6 7.1e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NSP11 PF06471.7 CEP16669.1 - 0.0072 14.5 0.0 0.0092 14.2 0.0 1.1 1 0 0 1 1 1 1 NSP11 SPOR PF05036.8 CEP16669.1 - 0.029 14.5 0.8 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain Ank_2 PF12796.2 CEP16670.1 - 3.1e-20 72.3 1.2 6.6e-11 42.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) TIG PF01833.19 CEP16670.1 - 2.8e-12 46.4 0.1 3.1e-11 43.1 0.0 2.6 2 0 0 2 2 2 1 IPT/TIG domain Ank PF00023.25 CEP16670.1 - 1.2e-11 43.8 0.3 4.1e-05 23.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CEP16670.1 - 1.4e-09 38.1 0.1 3.5e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP16670.1 - 2.5e-08 33.9 0.1 6.4e-06 26.2 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP16670.1 - 1.7e-06 27.7 0.2 0.0081 16.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Connexin_CCC PF10582.4 CEP16670.1 - 0.23 11.2 4.3 0.078 12.8 0.4 2.0 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain TOM13 PF08219.6 CEP16670.1 - 1.9 8.3 4.0 7.8 6.3 0.1 2.9 2 0 0 2 2 2 0 Outer membrane protein TOM13 Pkinase PF00069.20 CEP16671.1 - 4e-67 226.1 0.0 7.3e-67 225.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Asp_protease PF09668.5 CEP16671.1 - 5.5e-51 171.3 0.0 9.5e-51 170.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Pkinase_Tyr PF07714.12 CEP16671.1 - 1.1e-49 168.9 0.0 2.3e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ubiquitin PF00240.18 CEP16671.1 - 5.6e-11 41.6 0.7 1.2e-10 40.6 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.1 CEP16671.1 - 2.8e-09 37.3 0.2 1e-08 35.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP16671.1 - 6.7e-08 32.2 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease XPC-binding PF09280.6 CEP16671.1 - 3.5e-05 23.1 0.1 3.5e-05 23.1 0.1 2.6 2 0 0 2 2 2 1 XPC-binding domain RVP PF00077.15 CEP16671.1 - 0.00037 20.3 0.0 0.0013 18.6 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CEP16671.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease YrbL-PhoP_reg PF10707.4 CEP16671.1 - 0.047 13.0 0.1 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-C2H2 PF00096.21 CEP16672.1 - 5.7e-11 42.0 24.0 2.6e-05 24.2 0.1 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP16672.1 - 1.6e-08 34.4 21.1 1.5e-05 25.0 1.1 5.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP16672.1 - 1.5e-05 24.9 21.4 0.044 14.1 0.1 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger Pal1 PF08316.6 CEP16672.1 - 0.053 13.9 0.7 0.053 13.9 0.5 2.8 3 0 0 3 3 3 0 Pal1 cell morphology protein zf-C2H2_jaz PF12171.3 CEP16672.1 - 7.4 6.8 9.7 1e+02 3.2 0.2 4.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Maf PF02545.9 CEP16673.1 - 1.4e-48 164.6 0.0 1.6e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein zf-RVT PF13966.1 CEP16676.1 - 0.0017 18.6 0.2 0.0039 17.4 0.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Phage_integrase PF00589.17 CEP16677.1 - 0.0001 22.0 1.9 0.00015 21.4 1.3 1.2 1 0 0 1 1 1 1 Phage integrase family TBCC PF07986.7 CEP16677.1 - 0.053 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor C Apc4_WD40 PF12894.2 CEP16677.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain GIT_SHD PF08518.6 CEP16678.1 - 0.038 13.3 0.2 0.11 11.9 0.2 1.7 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT PIF1 PF05970.9 CEP16679.1 - 8.1e-14 51.3 0.9 2e-07 30.2 0.1 2.4 1 1 0 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 CEP16679.1 - 0.00034 18.5 0.0 0.0015 16.4 0.0 1.8 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.13 CEP16679.1 - 0.0029 17.1 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CEP16679.1 - 0.0041 16.3 0.0 0.0079 15.4 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein UvrD_C_2 PF13538.1 CEP16679.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 CEP16679.1 - 0.0075 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CEP16679.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 CEP16679.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 CEP16679.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CEP16679.1 - 0.031 14.0 0.0 0.095 12.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 CEP16679.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CEP16679.1 - 0.053 14.3 0.0 0.16 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CEP16679.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RhoGEF PF00621.15 CEP16682.1 - 7.4e-38 130.2 5.4 1.1e-37 129.6 2.2 2.0 2 0 0 2 2 2 1 RhoGEF domain Rsd_AlgQ PF04353.8 CEP16682.1 - 0.047 13.3 0.1 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Arrestin_C PF02752.17 CEP16683.1 - 5.3e-12 46.0 0.9 9.6e-06 25.7 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP16683.1 - 1.3e-05 25.0 0.0 0.0011 18.8 0.0 3.4 2 2 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CEP16683.1 - 0.039 13.4 0.1 0.19 11.1 0.0 2.2 2 1 0 2 2 2 0 Arrestin_N terminal like TIG PF01833.19 CEP16684.1 - 2.4e-11 43.4 2.4 3e-11 43.1 0.1 2.5 2 0 0 2 2 2 1 IPT/TIG domain DDE_3 PF13358.1 CEP16685.1 - 0.00077 19.2 0.0 0.0011 18.6 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease NDUF_B5 PF09781.4 CEP16685.1 - 0.071 12.3 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit p450 PF00067.17 CEP16686.1 - 7.1e-96 321.5 0.0 1.3e-95 320.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 CEP16686.1 - 3.2e-40 137.9 0.0 5.9e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CEP16686.1 - 1e-23 83.8 0.6 2.6e-23 82.6 0.4 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CEP16686.1 - 5e-19 68.8 0.0 1.5e-18 67.3 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CEP16686.1 - 0.014 15.3 0.0 7 6.5 0.0 2.6 1 1 0 2 2 2 0 Ferric reductase NAD binding domain GPP34 PF05719.6 CEP16687.1 - 0.0036 17.3 1.4 0.004 17.2 1.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SPC25 PF06703.6 CEP16687.1 - 0.079 12.5 0.7 0.11 12.0 0.5 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Spore_coat_CotO PF14153.1 CEP16687.1 - 0.12 11.7 9.1 0.15 11.5 6.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Phage_GP20 PF06810.6 CEP16687.1 - 0.35 10.3 25.3 0.051 13.0 12.4 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 FUSC PF04632.7 CEP16687.1 - 0.36 9.1 2.0 0.41 9.0 1.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family GBP_C PF02841.9 CEP16687.1 - 0.53 9.4 17.0 0.61 9.2 11.8 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Reo_sigmaC PF04582.7 CEP16687.1 - 0.57 9.3 8.0 0.74 8.9 5.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AKNA PF12443.3 CEP16687.1 - 0.85 9.6 15.8 0.97 9.4 1.5 2.9 1 1 1 2 2 2 0 AT-hook-containing transcription factor APG6 PF04111.7 CEP16687.1 - 0.97 8.4 20.4 1.3 8.0 14.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.1 CEP16687.1 - 1 8.2 7.2 1.4 7.8 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LUC7 PF03194.10 CEP16687.1 - 1.1 8.7 13.4 1.6 8.1 9.3 1.4 1 1 0 1 1 1 0 LUC7 N_terminus Med9 PF07544.8 CEP16687.1 - 1.5 8.6 17.2 1 9.1 6.5 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.7 CEP16687.1 - 2 8.1 14.5 0.23 11.2 2.1 2.8 1 1 1 2 2 2 0 Laminin Domain II Atg14 PF10186.4 CEP16687.1 - 2.7 6.8 19.6 0.6 9.0 9.1 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 CEP16687.1 - 3.4 7.6 11.5 0.92 9.4 2.2 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 CEP16687.1 - 4 7.2 14.2 3.9 7.2 0.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 CEP16687.1 - 4 7.4 22.3 0.37 10.8 7.8 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.4 CEP16687.1 - 5.1 7.3 8.4 3.6 7.8 3.4 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.5 CEP16687.1 - 9.6 6.3 15.1 8.5 6.4 9.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family COPI_assoc PF08507.5 CEP16688.1 - 4.8e-23 81.3 9.4 5.9e-23 81.0 6.5 1.1 1 0 0 1 1 1 1 COPI associated protein Neurensin PF14927.1 CEP16688.1 - 1.4 8.2 6.5 4.4 6.6 1.7 2.3 1 1 1 2 2 2 0 Neurensin TCR_zetazeta PF11628.3 CEP16688.1 - 2 7.9 5.1 2 7.9 0.1 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain PEX11 PF05648.9 CEP16689.1 - 4.6e-16 58.7 0.5 5e-14 52.1 0.2 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) EMP70 PF02990.11 CEP16690.1 - 1e-107 360.7 8.7 1.3e-107 360.4 6.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2306 PF10067.4 CEP16690.1 - 0.017 15.2 1.3 0.017 15.2 0.9 3.4 3 1 1 4 4 4 0 Predicted membrane protein (DUF2306) MARVEL PF01284.18 CEP16691.1 - 1.3e-08 34.7 8.9 2e-08 34.1 6.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain Cytadhesin_P30 PF07271.6 CEP16691.1 - 0.032 13.5 0.3 0.046 13.0 0.2 1.4 1 1 0 1 1 1 0 Cytadhesin P30/P32 2TM PF13239.1 CEP16691.1 - 0.33 11.0 4.7 1.7 8.7 3.3 2.2 1 1 0 1 1 1 0 2TM domain Ran_BP1 PF00638.13 CEP16693.1 - 3e-48 162.8 1.6 5.1e-48 162.1 1.1 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CEP16693.1 - 1.4e-06 27.9 0.4 6.1e-06 25.9 0.2 1.8 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 CEP16693.1 - 0.00032 20.3 2.7 0.00045 19.8 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WD40 PF00400.27 CEP16695.1 - 1.7e-17 62.5 0.2 1.5e-09 37.3 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat MBOAT_2 PF13813.1 CEP16697.1 - 7.9e-15 54.6 3.7 2.2e-14 53.2 2.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family LEA_2 PF03168.8 CEP16698.1 - 2.7e-05 24.4 0.0 4.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1360 PF07098.6 CEP16698.1 - 0.044 13.5 1.0 0.07 12.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) DOMON PF03351.12 CEP16698.1 - 0.097 12.6 0.4 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 DOMON domain WBP-1 PF11669.3 CEP16698.1 - 2.3 8.3 8.8 11 6.1 5.5 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 ETC_C1_NDUFA5 PF04716.9 CEP16699.1 - 7.4e-23 79.8 0.9 7.4e-23 79.8 0.7 1.8 2 0 0 2 2 2 1 ETC complex I subunit conserved region Topoisom_bac PF01131.15 CEP16700.1 - 5.5e-98 328.4 0.0 1.6e-97 326.8 0.0 1.7 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.17 CEP16700.1 - 1.1e-09 38.1 0.0 2.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain EF-hand_7 PF13499.1 CEP16700.1 - 3.9e-07 30.0 3.1 2.3e-06 27.6 1.4 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CEP16700.1 - 1.7e-06 27.3 3.9 0.00011 21.8 0.3 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 CEP16700.1 - 0.00033 19.7 3.3 0.073 12.4 0.2 3.2 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 CEP16700.1 - 0.011 15.7 0.1 0.035 14.1 0.1 1.9 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 CEP16700.1 - 0.2 11.0 1.1 12 5.4 0.1 2.6 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CEP16700.1 - 0.91 9.1 5.0 77 3.0 0.2 3.9 2 1 1 3 3 3 0 EF-hand domain pair MFS_1 PF07690.11 CEP16701.1 - 1.2e-36 126.1 29.4 2.1e-36 125.3 20.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP16701.1 - 7.2e-13 47.9 25.7 3.4e-12 45.6 17.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP16702.1 - 1.6e-34 119.2 31.6 1.6e-34 119.2 21.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nol1_Nop2_Fmu PF01189.12 CEP16704.1 - 5.1e-103 344.3 0.0 1.3e-102 343.0 0.0 1.6 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CEP16704.1 - 0.00058 19.4 0.0 0.0017 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CEP16704.1 - 0.0055 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CEP16704.1 - 0.32 11.6 0.0 0.32 11.6 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain DHFR_1 PF00186.14 CEP16705.1 - 5.5e-39 133.3 0.0 2.1e-38 131.4 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase CoaE PF01121.15 CEP16706.1 - 2.7e-50 170.2 0.4 3.3e-50 169.9 0.3 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 CEP16706.1 - 0.033 14.5 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ufd2P_core PF10408.4 CEP16707.1 - 2.2e-202 673.7 11.4 3.3e-202 673.1 7.9 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CEP16707.1 - 7.9e-23 80.2 0.2 3.4e-22 78.1 0.2 2.2 1 0 0 1 1 1 1 U-box domain MRP-L27 PF09809.4 CEP16708.1 - 1.4e-19 69.7 0.1 1.5e-19 69.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Cullin_binding PF03556.10 CEP16709.1 - 5.2e-33 113.6 0.8 1.2e-32 112.4 0.5 1.6 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 CEP16709.1 - 1.5e-07 30.8 0.1 2.9e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain GldM_N PF12081.3 CEP16709.1 - 0.054 13.0 1.5 0.18 11.2 0.2 1.9 2 0 0 2 2 2 0 GldM N-terminal domain AIM24 PF01987.12 CEP16710.1 - 4.6e-25 88.3 0.0 7.9e-25 87.5 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Nipped-B_C PF12830.2 CEP16711.1 - 2.8e-39 134.6 0.9 5.3e-38 130.5 0.2 2.7 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus IPK PF03770.11 CEP16711.1 - 4.5e-31 108.0 0.1 1.1e-30 106.7 0.1 1.7 1 0 0 1 1 1 1 Inositol polyphosphate kinase Cohesin_HEAT PF12765.2 CEP16711.1 - 2e-05 24.4 4.4 5e-05 23.1 0.6 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 CEP16711.1 - 0.00024 21.3 0.9 0.0087 16.3 0.3 3.3 3 0 0 3 3 3 1 HEAT repeats Mucin PF01456.12 CEP16711.1 - 0.0019 17.9 12.2 0.032 14.0 8.7 2.4 2 0 0 2 2 2 1 Mucin-like glycoprotein HEAT PF02985.17 CEP16711.1 - 0.003 17.4 4.0 3.7 7.8 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat CH PF00307.26 CEP16712.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain APC_CDC26 PF10471.4 CEP16712.1 - 0.032 14.9 8.3 0.032 14.9 5.8 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Lipase_GDSL PF00657.17 CEP16713.1 - 4.8e-14 52.7 0.4 7.7e-14 52.0 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP16713.1 - 1.8e-06 28.1 0.0 4.7e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_S8 PF00082.17 CEP16714.1 - 7e-46 156.6 7.0 1.1e-45 155.9 4.9 1.3 1 0 0 1 1 1 1 Subtilase family zf-CSL PF05207.8 CEP16714.1 - 2.8e-22 77.9 2.4 5e-22 77.1 1.7 1.4 1 0 0 1 1 1 1 CSL zinc finger Spb1_C PF07780.7 CEP16715.1 - 2e-69 233.3 30.2 2e-69 233.3 21.0 4.6 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 CEP16715.1 - 9.9e-55 185.3 0.1 2.2e-54 184.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CEP16715.1 - 2.8e-43 147.1 17.6 2.8e-43 147.1 12.2 6.2 4 2 1 7 7 7 1 Domain of unknown function (DUF3381) Adap_comp_sub PF00928.16 CEP16718.1 - 9.7e-88 293.6 0.0 1.2e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CEP16718.1 - 0.0042 16.7 0.2 0.0083 15.8 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Arrestin_C PF02752.17 CEP16718.1 - 0.048 13.7 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain PIG-S PF10510.4 CEP16719.1 - 4.1e-120 401.9 13.3 2.2e-113 379.6 5.7 2.2 1 1 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein HhH-GPD PF00730.20 CEP16719.1 - 1.8e-23 82.9 0.0 4.5e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 CEP16719.1 - 1e-17 63.5 0.4 2.7e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain HHH PF00633.18 CEP16719.1 - 0.00026 20.5 0.1 0.00076 19.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CEP16719.1 - 0.017 15.2 4.5 0.032 14.3 3.1 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.1 CEP16719.1 - 0.18 11.9 0.0 3.4 7.9 0.0 2.9 2 1 0 2 2 2 0 Helix-hairpin-helix domain zf-RVT PF13966.1 CEP16720.1 - 0.011 16.0 1.5 0.024 14.9 1.1 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.22 CEP16721.1 - 6.2e-22 78.0 0.0 9.4e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP16722.1 - 0.00017 21.2 0.4 0.00039 20.0 0.3 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 CEP16722.1 - 0.0022 17.8 0.7 0.0022 17.8 0.5 2.1 2 0 0 2 2 2 1 Zinc knuckle F-box-like PF12937.2 CEP16724.1 - 7.4e-06 25.6 0.2 1.7e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP16724.1 - 0.00014 21.4 0.1 0.00049 19.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain PIP5K PF01504.13 CEP16725.1 - 5e-63 212.5 0.3 1.1e-62 211.4 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CEP16725.1 - 1.1e-25 90.2 0.2 1.9e-25 89.4 0.2 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CEP16725.1 - 6.6e-14 51.5 11.5 1.9e-13 50.0 8.0 1.8 1 0 0 1 1 1 1 FYVE zinc finger RVT_1 PF00078.22 CEP16727.1 - 1.6e-10 40.6 0.0 2.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.12 CEP16728.1 - 0.1 11.4 2.8 0.11 11.2 1.9 1.0 1 0 0 1 1 1 0 Presenilin Ribosomal_L28e PF01778.12 CEP16728.1 - 0.53 10.6 6.5 0.96 9.8 4.5 1.4 1 0 0 1 1 1 0 Ribosomal L28e protein family zf-CCHC PF00098.18 CEP16729.1 - 2.2e-07 30.4 12.9 0.00012 21.8 1.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP16729.1 - 0.013 14.9 13.3 0.02 14.4 3.2 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CEP16732.1 - 0.00053 19.6 1.9 0.031 13.9 0.2 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CEP16732.1 - 1.2 9.2 6.4 1.4 9.0 1.2 2.5 2 0 0 2 2 2 0 DnaJ central domain PHD PF00628.24 CEP16732.1 - 8.6 6.1 9.7 0.86 9.3 0.2 3.4 3 0 0 3 3 3 0 PHD-finger SDA1 PF05285.7 CEP16733.1 - 7.3 5.7 13.0 12 5.0 9.0 1.4 1 0 0 1 1 1 0 SDA1 DDE_3 PF13358.1 CEP16735.1 - 3.7e-15 55.9 0.1 5e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 CEP16737.1 - 0.0021 17.4 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_29 PF13551.1 CEP16741.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 CEP16742.1 - 3e-29 101.6 0.0 5.6e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease UBN2_2 PF14227.1 CEP16743.1 - 0.015 14.8 0.9 0.034 13.7 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type COesterase PF00135.23 CEP16744.1 - 3.2e-80 270.3 0.0 2.3e-52 178.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Iso_dh PF00180.15 CEP16745.1 - 2.6e-97 325.9 0.0 1e-96 323.9 0.0 1.7 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Isochorismatase PF00857.15 CEP16746.1 - 7.2e-36 123.7 0.0 8e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NYN PF01936.13 CEP16746.1 - 0.0049 17.1 0.0 0.0063 16.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain CIAPIN1 PF05093.8 CEP16747.1 - 1.2e-24 86.2 1.3 1.7e-24 85.7 0.9 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis G-gamma PF00631.17 CEP16748.1 - 1.4e-15 56.7 0.2 1.7e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 GGL domain ERCC4 PF02732.10 CEP16749.1 - 2.4e-28 98.6 0.0 9.6e-28 96.7 0.0 2.1 1 0 0 1 1 1 1 ERCC4 domain Amino_oxidase PF01593.19 CEP16749.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Arm PF00514.18 CEP16750.1 - 3e-82 267.9 17.3 1.1e-13 50.4 0.1 9.4 9 1 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEP16750.1 - 7.2e-22 77.4 0.1 7.9e-07 29.2 0.0 6.0 2 1 5 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 CEP16750.1 - 3e-21 75.2 3.8 3e-05 24.3 0.0 6.8 5 3 3 8 8 8 4 HEAT-like repeat HEAT PF02985.17 CEP16750.1 - 1e-16 59.3 4.9 0.002 18.0 0.0 8.1 9 1 0 9 9 9 3 HEAT repeat Arm_2 PF04826.8 CEP16750.1 - 1.7e-08 33.9 0.0 0.09 11.8 0.1 4.4 2 1 3 5 5 5 4 Armadillo-like Adaptin_N PF01602.15 CEP16750.1 - 4.9e-06 25.1 0.0 0.00057 18.3 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 CEP16750.1 - 5.8e-06 24.8 0.3 4.9e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 CEP16750.1 - 6.8e-05 22.7 0.0 0.36 10.7 0.0 4.5 3 3 2 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.1 CEP16750.1 - 0.0055 16.6 5.5 2.3 8.1 0.1 4.0 3 2 1 4 4 4 3 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 CEP16750.1 - 0.073 13.5 0.2 9.3 7.0 0.0 4.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 CEP16750.1 - 0.13 12.6 0.1 4.6 7.6 0.0 3.0 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Complex1_LYR PF05347.10 CEP16751.1 - 3e-06 26.9 1.1 0.00011 21.8 0.7 2.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEP16751.1 - 0.0003 20.9 0.9 0.0037 17.4 0.6 2.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CEP16751.1 - 0.0013 19.1 0.4 0.0022 18.4 0.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like DDHD PF02862.12 CEP16752.1 - 7.6e-52 176.3 0.4 5.5e-50 170.2 0.0 2.4 2 0 0 2 2 2 1 DDHD domain WWE PF02825.15 CEP16752.1 - 0.0036 16.7 0.3 0.64 9.4 0.0 3.0 3 0 0 3 3 3 2 WWE domain CBFB_NFYA PF02045.10 CEP16753.1 - 2.5e-31 107.9 6.0 4.1e-31 107.2 4.1 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Nucleos_tra2_C PF07662.8 CEP16754.1 - 2.9e-68 229.4 7.8 6.1e-68 228.4 5.4 1.6 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CEP16754.1 - 1.1e-23 83.3 3.7 1.1e-23 83.3 2.5 3.2 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CEP16754.1 - 0.0077 16.1 5.7 0.0077 16.1 3.9 3.3 2 1 0 2 2 2 1 Nucleoside recognition Sec2p PF06428.6 CEP16755.1 - 3.2e-09 36.5 9.6 3.2e-09 36.5 6.6 3.4 3 0 0 3 3 3 2 GDP/GTP exchange factor Sec2p NIF PF03031.13 CEP16756.1 - 8.1e-12 45.0 4.2 6.6e-11 42.1 0.3 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Pkinase PF00069.20 CEP16757.1 - 6e-60 202.5 0.0 7.1e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16757.1 - 6.4e-20 71.3 0.0 2e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP16757.1 - 5.2e-06 25.6 0.0 0.0011 17.9 0.0 2.1 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 CEP16757.1 - 0.0017 18.1 0.1 0.0066 16.2 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP16757.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RDM PF11002.3 CEP16757.1 - 0.12 12.0 0.2 27 4.5 0.0 2.8 2 0 0 2 2 2 0 RFPL defining motif (RDM) GDA1_CD39 PF01150.12 CEP16758.1 - 1.7e-98 330.0 0.0 2.1e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CEP16758.1 - 0.066 12.3 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family zf-CCHC PF00098.18 CEP16759.1 - 0.0023 17.7 1.1 0.28 11.1 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle rve PF00665.21 CEP16760.1 - 5.5e-20 71.6 0.0 1.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP16760.1 - 9.1e-20 70.9 0.0 2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CEP16760.1 - 0.012 15.1 0.0 0.031 13.7 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RVT_3 PF13456.1 CEP16760.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like Pico_P1A PF02226.11 CEP16760.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) Cwf_Cwc_15 PF04889.7 CEP16761.1 - 0.00053 19.7 8.1 0.00083 19.1 5.6 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Retrotrans_gag PF03732.12 CEP16761.1 - 0.0047 16.9 2.7 0.0047 16.9 1.9 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein DUF3361 PF11841.3 CEP16761.1 - 0.32 10.6 3.8 0.18 11.5 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) FUN14 PF04930.10 CEP16761.1 - 0.7 10.2 2.9 18 5.6 0.1 2.5 2 0 0 2 2 2 0 FUN14 family Cwf_Cwc_15 PF04889.7 CEP16762.1 - 0.00069 19.3 12.8 0.00069 19.3 8.9 2.3 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein zf-CCHC PF00098.18 CEP16762.1 - 0.02 14.7 0.6 0.02 14.7 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle GlyL_C PF12524.3 CEP16762.1 - 1.9 8.4 6.8 20 5.2 2.0 2.8 2 1 0 2 2 2 0 dsDNA virus glycoprotein L C terminal zf-CCHC_3 PF13917.1 CEP16762.1 - 6.2 6.6 15.1 3.4 7.4 6.0 3.0 1 1 1 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 CEP16763.1 - 0.0015 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP16764.1 - 0.00078 18.8 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Baculo_p33 PF05214.7 CEP16766.1 - 0.023 13.9 0.1 0.17 11.0 0.0 1.9 1 1 1 2 2 2 0 Baculovirus P33 zf-CCHC PF00098.18 CEP16769.1 - 1.4e-05 24.7 15.6 0.00031 20.5 2.9 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CHC2 PF01807.15 CEP16769.1 - 0.014 14.9 0.7 0.021 14.3 0.1 1.6 1 1 1 2 2 2 0 CHC2 zinc finger zf-CCHC_2 PF13696.1 CEP16769.1 - 0.21 11.1 15.4 0.72 9.3 2.3 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEP16769.1 - 0.45 10.2 15.4 0.64 9.7 2.1 2.2 1 1 1 2 2 2 0 Zinc knuckle rve PF00665.21 CEP16771.1 - 0.0064 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain MULE PF10551.4 CEP16772.1 - 6.1e-08 32.7 0.1 1.5e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CEP16772.1 - 4.7e-07 28.7 0.4 4.7e-07 28.7 0.3 1.7 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 CEP16772.1 - 2.8e-05 24.5 0.2 0.00011 22.6 0.1 2.0 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.12 CEP16772.1 - 0.0002 20.7 0.2 0.00042 19.7 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger WRKY PF03106.10 CEP16772.1 - 0.00032 20.4 0.1 0.001 18.8 0.1 1.9 1 0 0 1 1 1 1 WRKY DNA -binding domain DDE_Tnp_IS240 PF13610.1 CEP16772.1 - 0.0053 16.7 0.0 5.6 6.9 0.1 2.9 2 0 0 2 2 2 2 DDE domain Peptidase_C97 PF05903.9 CEP16772.1 - 0.025 14.3 0.1 22 4.7 0.0 3.6 3 0 0 3 3 3 0 PPPDE putative peptidase domain DDE_Tnp_ISL3 PF01610.12 CEP16772.1 - 0.4 10.2 6.7 0.14 11.7 0.7 2.9 3 1 0 3 3 3 0 Transposase zf-CCHC PF00098.18 CEP16773.1 - 3e-08 33.1 13.0 3.7e-05 23.4 1.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP16773.1 - 0.0059 16.2 6.6 0.099 12.3 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP16773.1 - 0.017 14.5 5.9 0.017 14.5 4.1 2.4 1 1 1 2 2 2 0 Zinc knuckle DDE_3 PF13358.1 CEP16776.1 - 8.3e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rRNA_processing PF08524.6 CEP16776.1 - 1 9.1 4.6 0.17 11.6 0.5 1.7 2 1 0 2 2 2 0 rRNA processing CENP-B_N PF04218.8 CEP16778.1 - 0.00025 20.4 0.1 0.0031 16.8 0.1 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.11 CEP16778.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_32 PF13565.1 CEP16778.1 - 0.044 14.5 0.0 0.1 13.4 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain zf-CCHC PF00098.18 CEP16779.1 - 0.00032 20.4 3.0 0.00055 19.7 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle T3SS_LEE_assoc PF13327.1 CEP16779.1 - 0.12 11.8 0.4 0.22 11.0 0.3 1.3 1 0 0 1 1 1 0 Type III secretion system subunit FTA4 PF13093.1 CEP16780.1 - 0.0023 17.3 0.4 0.0048 16.3 0.3 1.5 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FemAB PF02388.11 CEP16780.1 - 0.0061 15.3 0.2 0.012 14.3 0.1 1.4 1 0 0 1 1 1 1 FemAB family FbpA PF05833.6 CEP16780.1 - 0.0074 14.8 0.1 0.013 14.0 0.1 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IncA PF04156.9 CEP16780.1 - 0.017 14.6 2.6 0.032 13.8 1.8 1.4 1 0 0 1 1 1 0 IncA protein Cluap1 PF10234.4 CEP16780.1 - 0.021 14.0 0.4 0.057 12.6 0.2 1.7 1 0 0 1 1 1 0 Clusterin-associated protein-1 Med9 PF07544.8 CEP16780.1 - 0.033 13.9 0.9 0.088 12.5 0.6 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Myc-LZ PF02344.10 CEP16780.1 - 0.076 12.6 1.2 0.15 11.6 0.9 1.5 1 0 0 1 1 1 0 Myc leucine zipper domain RICH PF05062.7 CEP16780.1 - 0.13 12.4 2.7 0.22 11.6 0.2 2.4 2 0 0 2 2 2 0 RICH domain DUF2630 PF10944.3 CEP16780.1 - 0.13 12.3 3.0 0.25 11.4 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) NEMO PF11577.3 CEP16780.1 - 0.13 11.9 1.4 0.25 11.0 0.9 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO RVT_1 PF00078.22 CEP16781.1 - 5.6e-13 48.7 0.2 8.6e-13 48.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP16782.1 - 8.1e-13 48.5 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP16782.1 - 2.4e-08 33.4 0.5 4.7e-08 32.5 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP16782.1 - 0.13 12.0 0.2 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-ISL3 PF14690.1 CEP16783.1 - 0.0065 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PIF1 PF05970.9 CEP16785.1 - 9.1e-30 103.8 0.1 7.4e-19 67.9 0.0 2.4 1 1 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 CEP16785.1 - 1.7e-20 73.5 0.1 4.4e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 CEP16785.1 - 1.4e-16 60.6 0.0 2.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 CEP16785.1 - 8.1e-05 22.7 0.1 0.00064 19.8 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CEP16785.1 - 0.00014 21.4 0.0 0.092 12.2 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CEP16785.1 - 0.0034 17.5 0.0 0.0091 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF3296 PF11726.3 CEP16785.1 - 0.007 15.9 0.3 0.13 11.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3296) AAA_19 PF13245.1 CEP16785.1 - 0.017 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IR1-M PF12185.3 CEP16785.1 - 0.18 11.5 2.2 0.26 11.0 0.1 2.4 2 1 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain AAA_16 PF13191.1 CEP16785.1 - 0.19 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Asp_protease_2 PF13650.1 CEP16786.1 - 5.4e-06 26.8 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CEP16786.1 - 0.0003 20.5 2.0 0.0003 20.5 1.4 2.5 1 1 1 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.1 CEP16786.1 - 0.0018 18.0 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.1 CEP16786.1 - 6.5 6.5 12.7 1.3 8.8 1.2 2.5 1 1 1 2 2 2 0 Zinc knuckle rve PF00665.21 CEP16787.1 - 2.8e-17 62.9 0.0 3.9e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP16787.1 - 0.0012 18.3 0.0 0.003 17.0 0.0 1.7 1 1 0 1 1 1 1 Integrase core domain IFNGR1 PF07140.6 CEP16787.1 - 0.043 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) rve PF00665.21 CEP16788.1 - 1.9e-31 108.6 0.0 2.6e-19 69.5 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.22 CEP16788.1 - 1.4e-17 63.8 0.2 1.4e-17 63.8 0.1 2.6 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP16788.1 - 2.2e-07 31.2 0.0 4.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 CEP16788.1 - 7.7e-06 25.3 0.2 0.18 11.3 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain RVP_2 PF08284.6 CEP16788.1 - 0.00022 21.1 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP16788.1 - 0.00045 19.9 0.1 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CEP16788.1 - 0.0013 18.6 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CEP16788.1 - 0.015 14.8 0.0 0.044 13.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease MAPKK1_Int PF08923.5 CEP16788.1 - 0.13 11.8 0.1 19 4.8 0.0 2.4 2 0 0 2 2 2 0 Mitogen-activated protein kinase kinase 1 interacting ADK PF00406.17 CEP16788.1 - 0.16 11.8 0.0 23 4.8 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase Retrotrans_gag PF03732.12 CEP16789.1 - 3.7e-06 26.9 0.1 6.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Transposase_21 PF02992.9 CEP16790.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Transposase family tnp2 FhuF PF06276.7 CEP16791.1 - 0.047 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Transposase_21 PF02992.9 CEP16793.1 - 1.3e-09 37.4 0.2 6.9e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 zf-C2H2_4 PF13894.1 CEP16793.1 - 0.088 13.1 2.2 1.5 9.3 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger CUE PF02845.11 CEP16797.1 - 0.056 12.9 1.1 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 CUE domain Chromo PF00385.19 CEP16798.1 - 2.7e-09 36.5 0.2 4.4e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Snf7 PF03357.16 CEP16799.1 - 6.2e-45 152.6 21.5 8.1e-45 152.2 14.9 1.1 1 0 0 1 1 1 1 Snf7 SopA PF13981.1 CEP16799.1 - 0.14 12.2 1.3 0.23 11.4 0.9 1.4 1 0 0 1 1 1 0 SopA-like central domain Ist1 PF03398.9 CEP16799.1 - 0.51 9.7 8.6 0.8 9.0 6.0 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway SOBP PF15279.1 CEP16799.1 - 1.1 9.5 5.0 1.4 9.2 3.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein TPR_MLP1_2 PF07926.7 CEP16799.1 - 3.8 7.2 15.2 1 9.0 8.3 1.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Allexi_40kDa PF05549.6 CEP16799.1 - 3.9 6.6 7.9 2.2 7.4 2.7 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF342 PF03961.8 CEP16799.1 - 4.6 5.5 9.0 2.1 6.6 4.8 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF342) RNA_pol_Rpb8 PF03870.10 CEP16800.1 - 1.4e-46 158.1 0.1 1.6e-46 157.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Ribosomal_L1 PF00687.16 CEP16801.1 - 7e-38 130.1 6.6 8.5e-38 129.8 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Homeobox_KN PF05920.6 CEP16801.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain BolA PF01722.13 CEP16802.1 - 2.5e-28 97.8 3.3 4.1e-28 97.1 2.3 1.3 1 0 0 1 1 1 1 BolA-like protein Sod_Fe_N PF00081.17 CEP16802.1 - 0.033 14.4 3.0 1.3 9.3 2.3 2.4 2 1 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ipi1_N PF12333.3 CEP16803.1 - 2.1e-16 59.7 0.6 6.7e-16 58.1 0.4 1.9 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation DUF2281 PF10047.4 CEP16803.1 - 0.0041 17.3 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2281) ABC_membrane PF00664.18 CEP16804.1 - 3.4e-56 190.6 22.2 3.2e-29 102.2 3.6 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP16804.1 - 2.1e-52 177.0 0.0 8.4e-32 110.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CEP16804.1 - 3.9e-10 39.3 5.9 0.0028 16.9 1.9 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEP16804.1 - 1.4e-06 28.8 1.6 0.0022 18.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CEP16804.1 - 4.1e-06 26.3 0.2 0.13 11.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 CEP16804.1 - 4.5e-06 25.7 0.0 0.053 12.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 CEP16804.1 - 2.5e-05 23.7 0.6 0.095 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CEP16804.1 - 5.2e-05 23.3 5.6 0.1 12.5 0.0 4.3 4 1 0 4 4 3 2 AAA domain Miro PF08477.8 CEP16804.1 - 7.6e-05 23.1 0.1 0.076 13.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 CEP16804.1 - 0.00011 21.8 0.2 0.57 9.5 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain AAA_17 PF13207.1 CEP16804.1 - 0.00015 22.5 0.4 0.35 11.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CEP16804.1 - 0.00061 19.6 0.1 0.065 13.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family IstB_IS21 PF01695.12 CEP16804.1 - 0.00063 19.2 0.1 0.69 9.3 0.0 3.4 4 0 0 4 4 3 1 IstB-like ATP binding protein DUF87 PF01935.12 CEP16804.1 - 0.00083 19.2 1.5 0.085 12.6 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 CEP16804.1 - 0.0013 18.4 1.1 1.4 8.6 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CEP16804.1 - 0.0014 18.5 0.1 0.66 9.8 0.1 3.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEP16804.1 - 0.0022 18.3 0.5 1.7 8.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 CEP16804.1 - 0.0029 17.4 0.2 28 4.7 0.0 3.7 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CEP16804.1 - 0.003 16.6 0.1 2.7 7.0 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 CEP16804.1 - 0.0032 16.6 0.1 0.4 9.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP16804.1 - 0.0049 17.0 5.7 0.5 10.4 0.3 3.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP16804.1 - 0.0052 16.7 1.8 2.9 7.8 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CEP16804.1 - 0.0055 16.6 0.2 1.2 9.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.10 CEP16804.1 - 0.0075 16.1 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 CEP16804.1 - 0.01 15.3 0.1 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 CEP16804.1 - 0.021 14.3 1.7 0.2 11.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CEP16804.1 - 0.061 12.9 3.9 1.9 8.0 0.1 2.9 3 0 0 3 3 2 0 NACHT domain AAA PF00004.24 CEP16804.1 - 0.069 13.3 0.2 7.8 6.7 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CEP16804.1 - 0.11 12.3 0.4 2 8.2 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 CEP16804.1 - 0.14 11.5 2.3 1.5 8.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_pol_Rpb2_5 PF04567.12 CEP16804.1 - 0.14 12.1 0.1 0.5 10.3 0.1 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 DUF106 PF01956.11 CEP16804.1 - 0.21 11.1 6.8 0.035 13.6 1.3 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 NB-ARC PF00931.17 CEP16804.1 - 0.23 10.2 3.7 0.31 9.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.9 CEP16804.1 - 0.23 11.1 0.7 54 3.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Alginate_lyase PF05426.7 CEP16805.1 - 4.9e-48 163.8 0.2 9.6e-48 162.8 0.1 1.5 1 0 0 1 1 1 1 Alginate lyase MAP65_ASE1 PF03999.7 CEP16805.1 - 7.8 4.9 20.8 29 3.0 14.4 1.9 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HAUS6_N PF14661.1 CEP16806.1 - 0.0036 16.7 6.7 0.0046 16.3 4.7 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Dishevelled PF02377.10 CEP16806.1 - 0.084 13.0 3.4 0.16 12.2 1.9 1.9 1 1 0 1 1 1 0 Dishevelled specific domain Gag_spuma PF03276.9 CEP16806.1 - 0.57 8.4 7.5 0.65 8.2 5.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein SOBP PF15279.1 CEP16806.1 - 1.5 9.1 9.0 1.7 8.9 6.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein HMG_box PF00505.14 CEP16807.1 - 1.7e-18 66.5 1.0 3.4e-18 65.6 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP16807.1 - 2e-08 34.4 0.5 4.7e-08 33.2 0.3 1.7 1 0 0 1 1 1 1 HMG-box domain Phage_T4_gp36 PF03903.8 CEP16807.1 - 0.076 13.0 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Phage T4 tail fibre AAA_12 PF13087.1 CEP16808.1 - 2.5e-38 131.4 0.0 4.8e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEP16808.1 - 1.5e-27 96.6 1.1 2.7e-13 50.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CEP16808.1 - 1.1e-07 31.6 0.0 0.00041 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CEP16808.1 - 3.4e-07 29.9 0.0 8.4e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CEP16808.1 - 0.00063 18.8 0.2 0.0095 14.9 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CEP16808.1 - 0.0034 17.5 0.4 1.2 9.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 CEP16808.1 - 0.0045 16.2 0.1 0.019 14.1 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.16 CEP16808.1 - 0.0083 15.4 2.0 0.063 12.5 1.4 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 CEP16808.1 - 0.057 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pyr_redox_2 PF07992.9 CEP16809.1 - 4.8e-44 150.6 0.0 9.9e-44 149.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CEP16809.1 - 1.1e-31 109.0 1.2 1.8e-31 108.4 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CEP16809.1 - 4.4e-20 71.8 2.5 2.3e-17 63.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP16809.1 - 4.7e-15 56.2 0.1 6e-13 49.3 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEP16809.1 - 1.6e-06 27.2 0.1 6.3e-05 22.0 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 CEP16809.1 - 5.3e-06 25.7 0.1 7.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CEP16809.1 - 9.1e-06 24.3 3.2 0.021 13.3 0.4 3.9 3 1 1 4 4 4 1 HI0933-like protein DAO PF01266.19 CEP16809.1 - 2.7e-05 23.2 8.2 0.0004 19.4 0.6 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP16809.1 - 0.00012 22.0 4.8 0.00036 20.4 3.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 CEP16809.1 - 0.00021 20.7 0.7 0.00069 19.0 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 CEP16809.1 - 0.00049 19.7 2.0 0.0048 16.4 0.0 2.7 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 CEP16809.1 - 0.0011 17.9 7.4 0.1 11.4 2.7 3.4 3 1 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 CEP16809.1 - 0.0012 18.0 0.0 0.0012 18.0 0.0 2.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CEP16809.1 - 0.0015 17.4 9.6 0.004 16.0 2.3 3.5 3 1 1 4 4 4 1 FAD binding domain 3HCDH_N PF02737.13 CEP16809.1 - 0.0016 18.1 0.9 0.0031 17.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 CEP16809.1 - 0.0055 15.8 0.8 0.017 14.2 0.2 2.0 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 CEP16809.1 - 0.045 13.4 2.3 0.06 13.0 0.0 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 CEP16809.1 - 0.072 13.3 0.1 4 7.7 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 CEP16809.1 - 2.6 7.0 5.7 28 3.6 0.1 3.0 2 1 1 3 3 3 0 FAD binding domain zf-Tim10_DDP PF02953.10 CEP16810.1 - 6.2e-21 73.4 0.2 7.8e-21 73.1 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CEP16810.1 - 0.007 15.8 0.8 0.0085 15.5 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Inh PF02974.9 CEP16810.1 - 0.063 12.8 0.1 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 Protease inhibitor Inh DUF3398 PF11878.3 CEP16810.1 - 0.066 13.0 0.0 0.079 12.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) Glyco_transf_20 PF00982.16 CEP16811.1 - 1e-196 654.0 0.0 1.4e-196 653.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEP16811.1 - 4.3e-58 195.9 0.0 1.1e-57 194.6 0.0 1.7 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CEP16811.1 - 2.4e-06 27.3 0.0 6.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 CEP16811.1 - 0.012 15.7 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CEP16811.1 - 0.014 14.8 0.1 0.56 9.5 0.0 3.0 1 1 0 1 1 1 0 Glycosyl transferases group 1 Aminotran_4 PF01063.14 CEP16813.1 - 3.4e-22 79.0 0.0 4.2e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV potato_inhibit PF00280.13 CEP16813.1 - 0.0094 16.0 0.1 0.026 14.6 0.1 1.7 1 0 0 1 1 1 1 Potato inhibitor I family Ribosomal_L7Ae PF01248.21 CEP16814.1 - 1.1e-22 79.3 1.4 2.1e-22 78.4 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family KAP_NTPase PF07693.9 CEP16814.1 - 0.04 12.9 0.1 0.06 12.3 0.1 1.3 1 0 0 1 1 1 0 KAP family P-loop domain RasGAP PF00616.14 CEP16815.1 - 2.7e-53 180.5 0.0 2.7e-53 180.5 0.0 2.8 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CEP16815.1 - 3.9e-29 101.1 3.9 3.9e-29 101.1 2.7 3.0 2 1 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 CEP16815.1 - 6.7 7.1 14.3 11 6.4 0.6 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF972) Abhydrolase_3 PF07859.8 CEP16816.1 - 2.3e-20 73.0 0.0 4.6e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PPR_2 PF13041.1 CEP16816.1 - 3.7e-16 58.8 0.0 2.6e-09 36.9 0.0 2.9 2 1 0 2 2 2 2 PPR repeat family PPR PF01535.15 CEP16816.1 - 4.1e-08 32.6 0.2 0.00027 20.6 0.0 4.1 3 1 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 CEP16816.1 - 1.4e-07 31.1 0.1 0.012 15.8 0.0 4.0 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEP16816.1 - 9.5e-05 21.8 0.0 0.31 10.5 0.0 3.6 3 0 0 3 3 3 2 PPR repeat Trehalase PF01204.13 CEP16818.1 - 2.6e-174 580.6 0.6 3.2e-174 580.3 0.4 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CEP16818.1 - 2.4e-12 45.9 0.1 7.2e-12 44.4 0.1 1.9 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DisA-linker PF10635.4 CEP16818.1 - 0.092 12.2 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Cyclin PF08613.6 CEP16819.1 - 2.4e-39 135.1 0.2 4.1e-39 134.3 0.2 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP16819.1 - 0.00079 18.9 0.3 0.002 17.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain RBD-FIP PF09457.5 CEP16819.1 - 0.023 14.4 0.4 0.055 13.2 0.2 1.6 1 0 0 1 1 1 0 FIP domain A_amylase_inhib PF01356.14 CEP16819.1 - 0.099 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Alpha amylase inhibitor DUF2215 PF10225.4 CEP16820.1 - 0.44 9.9 2.4 0.48 9.8 1.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Apis_Csd PF11671.3 CEP16820.1 - 1.8 8.3 8.5 1.2 8.8 5.1 1.3 1 1 0 1 1 1 0 Complementary sex determiner protein MAS20 PF02064.10 CEP16820.1 - 1.9 8.4 7.2 0.95 9.3 3.8 1.5 1 1 0 1 1 1 0 MAS20 protein import receptor HTH_Tnp_Tc3_2 PF01498.13 CEP16822.1 - 0.13 12.3 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Transposase DUF3824 PF12868.2 CEP16824.1 - 0.057 14.3 0.1 0.081 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TM2 PF05154.11 CEP16826.1 - 2.2e-15 56.5 7.5 4.5e-15 55.5 5.2 1.5 1 0 0 1 1 1 1 TM2 domain DUF4131 PF13567.1 CEP16826.1 - 0.053 12.9 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Polysacc_synt PF01943.12 CEP16826.1 - 0.075 12.2 1.6 0.22 10.7 0.0 1.9 1 1 0 2 2 2 0 Polysaccharide biosynthesis protein RRM_1 PF00076.17 CEP16827.1 - 8.3e-19 66.9 0.0 1.5e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16827.1 - 6e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16827.1 - 1e-05 25.2 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.18 CEP16828.1 - 3.2e-16 59.3 0.1 2.6e-14 53.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP16828.1 - 7.9e-07 28.4 0.6 5.7e-05 22.4 0.2 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 CEP16828.1 - 8.9e-06 24.9 0.5 0.00016 20.8 0.1 2.2 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CEP16828.1 - 2.6e-05 23.4 0.1 5.7e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 CEP16828.1 - 7.7e-05 21.6 0.1 0.00012 21.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 CEP16828.1 - 0.0053 16.5 4.1 0.33 10.7 0.1 3.0 2 1 1 3 3 3 2 Dynamin family PduV-EutP PF10662.4 CEP16828.1 - 0.014 14.8 0.1 0.52 9.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CEP16828.1 - 0.034 13.1 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Septin MobB PF03205.9 CEP16828.1 - 0.037 13.7 0.3 0.074 12.7 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.17 CEP16828.1 - 0.049 13.0 0.2 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Ras family Miro PF08477.8 CEP16828.1 - 0.12 12.8 0.3 0.56 10.7 0.1 2.1 2 1 0 2 2 2 0 Miro-like protein Telomerase_RBD PF12009.3 CEP16829.1 - 1.1e-32 112.7 12.8 6e-32 110.3 4.6 2.8 2 0 0 2 2 2 2 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CEP16829.1 - 1.9e-12 46.9 2.0 5.5e-12 45.4 0.3 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CIA30 PF08547.7 CEP16831.1 - 3.5e-43 147.1 0.0 4.2e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RVT_1 PF00078.22 CEP16833.1 - 6.8e-17 61.5 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EphA2_TM PF14575.1 CEP16834.1 - 0.073 13.4 0.2 3.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SIR2 PF02146.12 CEP16835.1 - 3.5e-37 127.8 0.0 5.2e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CEP16835.1 - 0.011 15.4 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF3752 PF12572.3 CEP16835.1 - 0.083 13.0 0.3 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) zf-CCCH_2 PF14608.1 CEP16836.1 - 3.1e-06 26.9 17.3 0.00019 21.3 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CEP16836.1 - 0.019 14.6 7.4 0.47 10.2 5.2 2.4 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.10 CEP16836.1 - 0.036 13.5 0.3 0.071 12.6 0.2 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region PAS_3 PF08447.6 CEP16838.1 - 1.3e-12 47.6 2.5 2.7e-12 46.6 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CEP16838.1 - 5.3e-10 39.5 0.0 2e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 CEP16838.1 - 1.1e-09 38.0 0.0 1.1e-09 38.0 0.0 2.8 3 0 0 3 3 3 1 PAS fold CENP-M PF11111.3 CEP16838.1 - 5.9e-07 28.8 0.8 1.1e-06 27.9 0.5 1.3 1 0 0 1 1 1 1 Centromere protein M (CENP-M) GATA PF00320.22 CEP16838.1 - 9.6e-06 24.8 2.6 2.2e-05 23.7 1.8 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 CEP16838.1 - 0.016 15.2 2.8 0.023 14.7 0.0 2.5 2 0 0 2 2 2 0 PAS fold Cyclin PF08613.6 CEP16838.1 - 0.026 14.9 3.0 0.052 13.9 0.0 2.7 2 0 0 2 2 2 0 Cyclin Suf PF05843.9 CEP16838.1 - 0.57 9.8 25.4 0.0099 15.6 5.8 3.2 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) SNF2_N PF00176.18 CEP16839.1 - 2e-81 273.1 1.1 2e-81 273.1 0.7 3.3 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP16839.1 - 1.3e-16 60.1 0.0 6.9e-16 57.8 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 CEP16839.1 - 4.6e-15 55.1 8.2 4.6e-15 55.1 5.7 3.1 3 0 0 3 3 3 1 HSA SnAC PF14619.1 CEP16839.1 - 5.7e-15 55.2 5.6 5.7e-15 55.2 3.9 3.9 3 2 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex SR-25 PF10500.4 CEP16840.1 - 0.00013 21.5 4.6 0.00013 21.5 3.2 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Drf_GBD PF06371.8 CEP16841.1 - 1.7e-15 56.8 0.1 3.9e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF1643 PF07799.7 CEP16841.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) KH_1 PF00013.24 CEP16842.1 - 1.4e-26 91.8 0.0 2.9e-09 36.4 0.0 7.9 8 0 0 8 8 8 3 KH domain KH_3 PF13014.1 CEP16842.1 - 1.8e-21 75.3 0.1 2.4e-07 30.2 0.0 6.4 6 0 0 6 6 6 4 KH domain HATPase_c_5 PF14501.1 CEP16842.1 - 0.056 13.1 0.4 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 GHKL domain ArsA_ATPase PF02374.10 CEP16843.1 - 1.9e-113 378.5 1.3 2.1e-113 378.3 0.9 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CEP16843.1 - 5e-15 55.4 0.1 8.4e-15 54.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CEP16843.1 - 2.8e-08 33.8 0.0 8e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CEP16843.1 - 2.3e-05 23.7 0.0 5.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CEP16843.1 - 9.4e-05 21.9 1.2 0.00053 19.4 0.1 2.4 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CEP16843.1 - 0.00011 21.6 0.0 0.00033 20.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain YhjQ PF06564.7 CEP16843.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein MipZ PF09140.6 CEP16843.1 - 0.012 14.7 0.2 0.021 13.9 0.1 1.6 1 1 0 1 1 1 0 ATPase MipZ AAA_19 PF13245.1 CEP16843.1 - 0.031 14.0 0.0 0.084 12.6 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 CEP16843.1 - 0.034 13.0 0.0 0.077 11.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 CEP16843.1 - 0.053 12.7 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 CEP16843.1 - 0.081 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DnaJ PF00226.26 CEP16844.1 - 4.4e-28 96.8 2.5 6.7e-28 96.2 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CEP16844.1 - 2.8e-21 75.1 0.1 1.2e-16 60.4 0.0 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CEP16844.1 - 8.1e-13 48.2 21.9 1.4e-12 47.5 15.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CEP16844.1 - 0.76 9.4 12.9 0.23 11.1 2.0 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF1446 PF07287.6 CEP16845.1 - 7.7e-110 366.7 0.0 9.2e-110 366.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Ricin_B_lectin PF00652.17 CEP16846.1 - 3.8e-05 23.7 2.9 0.032 14.2 0.8 2.6 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP16846.1 - 0.028 14.7 0.6 0.81 10.0 0.2 2.4 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Ribosomal_S16 PF00886.14 CEP16847.1 - 4.5e-27 93.5 0.1 5.9e-27 93.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 SPX PF03105.14 CEP16848.1 - 2.5e-38 132.4 9.9 5.4e-38 131.3 6.8 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CEP16848.1 - 2.8e-29 102.3 34.6 4.1e-29 101.7 24.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CEP16848.1 - 1.3e-08 33.8 20.5 1.3e-08 33.8 14.2 2.9 1 1 2 3 3 3 2 Citrate transporter Acid_PPase PF12689.2 CEP16849.1 - 6.1e-52 175.6 0.0 7.5e-52 175.3 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase SNAP PF14938.1 CEP16850.1 - 1.3e-69 234.4 23.9 7.9e-58 195.8 12.0 2.4 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Arrestin_N PF00339.24 CEP16850.1 - 1.5e-12 47.5 0.0 9.5e-12 44.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain TPR_12 PF13424.1 CEP16850.1 - 0.00011 22.0 11.8 0.0036 17.2 2.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEP16850.1 - 0.018 14.6 12.6 0.081 12.5 3.6 3.3 3 0 0 3 3 3 0 TPR repeat NSF PF02071.15 CEP16850.1 - 0.097 13.2 17.2 9.3 7.3 0.1 6.8 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.23 CEP16850.1 - 5.5 6.7 11.8 2.4 7.9 0.1 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 CEP16851.1 - 2.7e-62 210.2 0.0 3.4e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16851.1 - 5e-39 133.9 0.0 6.5e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP16851.1 - 0.00088 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP16851.1 - 0.036 13.7 0.0 0.39 10.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CEP16851.1 - 0.045 12.8 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CEP16851.1 - 0.063 12.6 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DDE_3 PF13358.1 CEP16852.1 - 2.9e-07 30.3 0.1 3.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3870 PF12986.2 CEP16852.1 - 0.025 14.7 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Clusterin PF01093.12 CEP16853.1 - 0.01 14.7 0.5 0.012 14.4 0.4 1.1 1 0 0 1 1 1 0 Clusterin PH_9 PF15410.1 CEP16854.1 - 4e-12 46.3 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEP16854.1 - 1.7e-05 24.9 0.5 4.2e-05 23.6 0.0 1.9 2 1 0 2 2 2 1 PH domain HTH_Tnp_Tc3_2 PF01498.13 CEP16855.1 - 1.6e-08 34.4 0.0 3.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 CEP16855.1 - 2.1e-05 24.3 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP16855.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3069 PF11269.3 CEP16856.1 - 0.15 12.1 0.2 0.25 11.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3069) Sugar_tr PF00083.19 CEP16857.1 - 1.2e-71 241.6 11.2 3.8e-71 240.0 7.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP16857.1 - 1.5e-08 33.8 16.7 5.8e-05 21.9 9.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin PF08613.6 CEP16858.1 - 2e-09 38.0 0.1 2.6e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP16858.1 - 9.3e-09 34.9 0.1 1.7e-08 34.0 0.1 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain Mgr1 PF08602.5 CEP16858.1 - 0.029 13.3 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DNA_pol_A_exo1 PF01612.15 CEP16859.1 - 3.3e-08 33.2 0.0 5.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Abhydrolase_6 PF12697.2 CEP16862.1 - 2e-29 103.0 0.0 2.8e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metallophos_2 PF12850.2 CEP16862.1 - 2e-19 69.9 0.0 3.8e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Abhydrolase_1 PF00561.15 CEP16862.1 - 7.5e-18 64.9 0.0 3e-16 59.7 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP16862.1 - 2.1e-11 43.7 0.0 1.1e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Metallophos PF00149.23 CEP16862.1 - 9.2e-06 25.1 0.1 0.053 12.9 0.0 2.6 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Hydrolase_4 PF12146.3 CEP16862.1 - 0.00085 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CEP16862.1 - 0.00094 18.4 0.0 0.38 9.9 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 CEP16862.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 CEP16862.1 - 0.015 14.7 0.0 0.86 8.9 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 CEP16862.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Syja_N PF02383.13 CEP16863.1 - 3.7e-92 308.5 3.2 8.6e-92 307.3 2.2 1.6 1 1 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 CEP16863.1 - 2.1e-28 97.9 0.0 4.5e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase DDE_3 PF13358.1 CEP16864.1 - 2.9e-09 36.8 0.4 7.9e-08 32.1 0.2 2.4 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP16864.1 - 4.4e-06 26.6 2.0 5.4e-06 26.3 0.2 2.0 2 0 0 2 2 2 1 Transposase HTH_7 PF02796.10 CEP16864.1 - 0.0024 17.6 1.0 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.1 CEP16864.1 - 0.0027 17.8 0.3 0.14 12.3 0.0 2.5 2 1 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.14 CEP16864.1 - 0.02 14.6 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_DeoR PF08220.7 CEP16864.1 - 0.06 12.8 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_32 PF13565.1 CEP16864.1 - 0.075 13.8 0.1 0.21 12.4 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 CEP16864.1 - 0.12 11.9 0.2 0.77 9.3 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Sel1 PF08238.7 CEP16865.1 - 1.3e-43 146.4 11.4 4.8e-09 36.5 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_11 PF13414.1 CEP16865.1 - 3.1e-05 23.5 13.5 0.019 14.5 0.2 5.8 4 1 1 5 5 5 2 TPR repeat TPR_6 PF13174.1 CEP16865.1 - 0.0012 19.1 4.8 10 6.8 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP16865.1 - 0.039 14.5 3.2 17 6.3 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 CEP16865.1 - 0.078 13.2 0.6 24 5.4 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEP16865.1 - 0.35 11.6 10.7 65 4.3 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP16865.1 - 0.66 9.6 8.4 3.9 7.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 CEP16865.1 - 1.1 9.2 9.2 12 5.8 0.0 4.7 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 CEP16865.1 - 1.7 8.7 10.2 13 5.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Tmemb_14 PF03647.8 CEP16866.1 - 1.6e-18 66.8 11.9 5.4e-18 65.1 8.3 1.7 1 1 0 1 1 1 1 Transmembrane proteins 14C cNMP_binding PF00027.24 CEP16866.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF3353 PF11833.3 CEP16866.1 - 0.17 11.3 2.4 0.19 11.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Wzy_C PF04932.10 CEP16866.1 - 0.52 10.0 4.8 0.21 11.3 1.9 1.5 1 1 0 1 1 1 0 O-Antigen ligase FUSC_2 PF13515.1 CEP16866.1 - 0.76 9.6 5.5 1.7 8.5 3.6 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein-like O-antigen_lig PF13425.1 CEP16866.1 - 3.6 7.5 8.2 7.7 6.4 5.7 1.6 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF1768 PF08719.6 CEP16867.1 - 4.1e-07 29.8 0.1 1.3e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Dimer_Tnp_hAT PF05699.9 CEP16867.1 - 0.035 13.7 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region HTH_32 PF13565.1 CEP16867.1 - 0.078 13.7 0.1 0.38 11.5 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain START PF01852.14 CEP16869.1 - 1e-10 41.2 0.2 1.6e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 START domain TBP PF00352.16 CEP16870.1 - 0.029 13.7 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) DUF2152 PF10222.4 CEP16870.1 - 0.14 10.3 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Acetyltransf_9 PF13527.1 CEP16870.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RabGAP-TBC PF00566.13 CEP16871.1 - 9.6e-27 93.8 0.9 9.6e-27 93.8 0.6 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FlaC_arch PF05377.6 CEP16871.1 - 5.6 6.9 7.4 12 5.8 3.0 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 CEP16871.1 - 7.7 6.3 16.4 4.2 7.1 0.0 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF972 PF06156.8 CEP16871.1 - 7.8 6.9 37.5 3.2 8.1 6.2 5.4 2 2 2 4 4 4 0 Protein of unknown function (DUF972) Velvet PF11754.3 CEP16872.1 - 5.2e-67 225.3 0.1 7.6e-67 224.8 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Glyco_transf_49 PF13896.1 CEP16873.1 - 8.3e-19 67.8 1.4 3.9e-13 49.1 0.1 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan GPS PF01825.16 CEP16875.1 - 0.013 15.5 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain Pyr_redox PF00070.22 CEP16876.1 - 1.2e-12 48.0 0.0 2.1e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP16876.1 - 0.0031 17.5 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEP16876.1 - 0.0076 16.1 0.0 0.0094 15.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEP16876.1 - 0.019 13.8 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CEP16876.1 - 0.045 14.0 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Sel1 PF08238.7 CEP16877.1 - 3.1e-28 97.5 14.0 6.3e-08 33.0 0.0 7.2 7 0 0 7 7 7 6 Sel1 repeat Zn_clus PF00172.13 CEP16878.1 - 5.9e-09 35.6 12.5 1.2e-08 34.6 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_33 PF10017.4 CEP16879.1 - 3.1e-34 117.6 0.5 5.7e-34 116.7 0.4 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 CEP16879.1 - 1.7e-31 109.5 3.1 4e-16 59.1 0.1 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 CEP16879.1 - 1.7e-06 28.3 1.7 5.2e-06 26.8 1.2 1.9 1 0 0 1 1 1 1 DinB superfamily TrkH PF02386.11 CEP16882.1 - 5.2e-82 275.2 10.1 3.1e-79 266.1 4.2 2.1 2 0 0 2 2 2 2 Cation transport protein PIN_3 PF13470.1 CEP16882.1 - 0.033 14.8 1.5 0.29 11.7 0.0 2.5 2 0 0 2 2 2 0 PIN domain PPR_2 PF13041.1 CEP16883.1 - 3e-11 43.0 0.3 0.0045 16.9 0.0 4.8 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 CEP16883.1 - 3.2e-07 30.1 0.1 0.58 10.5 0.0 4.7 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 CEP16883.1 - 0.00019 21.1 0.7 0.16 12.0 0.0 4.8 5 1 0 5 5 5 1 PPR repeat DUF1786 PF08735.5 CEP16883.1 - 0.0024 17.0 0.1 0.0037 16.4 0.1 1.2 1 0 0 1 1 1 1 Putative pyruvate format-lyase activating enzyme (DUF1786) Globin PF00042.17 CEP16883.1 - 0.12 12.7 1.1 0.66 10.3 0.0 2.6 3 0 0 3 3 3 0 Globin WD40 PF00400.27 CEP16884.1 - 3.5e-14 52.0 1.1 0.92 9.4 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat G-patch PF01585.18 CEP16885.1 - 3.2e-10 39.6 1.4 8.8e-10 38.2 1.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CEP16885.1 - 0.03 14.1 1.0 0.03 14.1 0.7 2.9 2 1 0 2 2 2 0 DExH-box splicing factor binding site ISG65-75 PF11727.3 CEP16885.1 - 0.042 12.8 20.0 0.097 11.7 13.9 1.6 1 0 0 1 1 1 0 Invariant surface glycoprotein WD40 PF00400.27 CEP16887.1 - 4.3e-31 105.6 15.7 5.5e-09 35.5 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CEP16887.1 - 4.6e-05 23.2 4.0 0.0042 16.8 1.6 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-C2H2 PF00096.21 CEP16888.1 - 6.7e-16 57.5 13.9 0.00062 19.9 0.3 5.0 3 1 1 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP16888.1 - 2.4e-12 46.2 12.3 0.0012 19.0 0.1 5.0 4 1 1 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP16888.1 - 0.00016 21.8 20.6 0.012 15.9 0.2 5.5 5 1 0 5 5 5 2 Zinc-finger double domain CCAP PF11105.3 CEP16888.1 - 0.24 11.1 2.3 0.95 9.1 0.1 2.3 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a PAT1 PF09770.4 CEP16888.1 - 1.6 6.8 55.7 2 6.5 38.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CHORD PF04968.7 CEP16888.1 - 8.3 6.7 21.8 1.9 8.8 0.6 4.8 3 1 2 5 5 5 0 CHORD Pkinase PF00069.20 CEP16889.1 - 1e-62 211.6 0.2 8.8e-37 126.6 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16889.1 - 8.2e-41 139.7 0.2 1.3e-27 96.5 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEP16889.1 - 0.00047 19.2 0.0 0.34 9.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PALP PF00291.20 CEP16890.1 - 1.3e-63 215.1 0.1 1.6e-63 214.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CEP16890.1 - 3.6e-14 52.2 0.2 5.5e-09 35.6 0.0 3.1 3 1 0 3 3 3 2 CBS domain ChAPs PF09295.5 CEP16892.1 - 6.8e-130 433.3 3.3 4.6e-105 351.6 0.1 3.1 2 1 1 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CEP16892.1 - 4.2e-06 27.0 2.1 0.091 13.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP16892.1 - 0.00031 20.7 4.7 0.064 13.3 0.3 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CEP16892.1 - 0.0035 16.9 5.2 0.44 10.2 0.1 3.9 4 1 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 CEP16892.1 - 0.02 15.5 2.0 98 4.0 0.0 5.2 4 2 2 6 6 6 0 Tetratricopeptide repeat AAT PF03417.11 CEP16892.1 - 0.034 13.6 0.3 0.057 12.8 0.2 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TPR_8 PF13181.1 CEP16892.1 - 0.041 13.6 3.1 8.2 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP16892.1 - 1.2 9.2 7.3 15 5.8 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 CEP16893.1 - 2.4e-18 65.9 0.1 9e-18 64.1 0.0 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CEP16893.1 - 4.6e-08 33.1 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal TetR_C_5 PF08360.6 CEP16893.1 - 0.083 12.8 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 QacR-like protein, C-terminal region GalKase_gal_bdg PF10509.4 CEP16893.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Ribosomal_S10 PF00338.17 CEP16894.1 - 4e-32 109.9 0.9 5.4e-32 109.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MFS_1 PF07690.11 CEP16895.1 - 1.2e-32 112.9 26.7 2.1e-23 82.6 1.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP16895.1 - 1.6e-30 106.1 17.6 2.2e-23 82.5 0.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter NfeD PF01957.13 CEP16895.1 - 0.032 14.3 0.1 0.032 14.3 0.1 3.9 3 2 1 4 4 4 0 NfeD-like C-terminal, partner-binding DUF1279 PF06916.8 CEP16896.1 - 1.6e-18 66.7 0.4 2e-18 66.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DAGK_cat PF00781.19 CEP16897.1 - 4.4e-25 87.5 0.0 7.2e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peptidase_M3 PF01432.15 CEP16898.1 - 1.2e-121 407.0 0.0 1.6e-121 406.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CEP16898.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DUF2404 PF10296.4 CEP16899.1 - 7.8e-09 35.5 1.8 2.2e-05 24.4 0.0 2.9 3 0 0 3 3 3 2 Putative integral membrane protein conserved region (DUF2404) Metallophos PF00149.23 CEP16900.1 - 7.1e-40 136.5 0.4 1e-39 136.0 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP16900.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-H2C2_2 PF13465.1 CEP16901.1 - 2e-10 40.4 8.5 3e-07 30.3 2.4 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP16901.1 - 0.00023 21.2 19.1 0.0024 18.0 2.8 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP16901.1 - 0.00031 20.9 3.7 0.00031 20.9 2.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CEP16901.1 - 0.00081 19.4 3.8 0.011 15.8 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CEP16901.1 - 0.03 14.4 5.7 0.51 10.4 0.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MRP-S25 PF13741.1 CEP16902.1 - 7.7e-44 149.8 0.4 9.1e-44 149.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 CEP16902.1 - 0.0072 16.2 1.0 3.1 7.7 0.1 2.7 2 1 1 3 3 3 2 Mitochondrial ribosomal protein S23 U1snRNP70_N PF12220.3 CEP16905.1 - 4e-26 91.1 1.6 7.2e-26 90.3 1.1 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 CEP16905.1 - 1.2e-17 63.2 0.0 2.5e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16905.1 - 4.7e-16 58.5 0.0 9.8e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16905.1 - 1.6e-10 40.6 0.0 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FadA PF09403.5 CEP16905.1 - 0.039 13.9 1.3 0.071 13.1 0.9 1.3 1 0 0 1 1 1 0 Adhesion protein FadA PAP_central PF04928.12 CEP16906.1 - 3.3e-91 304.5 0.0 4.4e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CEP16906.1 - 7.8e-39 132.7 0.0 1.2e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CEP16906.1 - 2.5e-05 24.5 0.0 5.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain RVT_1 PF00078.22 CEP16907.1 - 4.8e-27 94.7 0.1 7.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 CEP16908.1 - 3.2e-59 200.2 0.0 2.1e-56 190.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16908.1 - 7.3e-27 94.0 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP16908.1 - 1.4e-07 30.7 0.2 4.5e-06 25.8 0.1 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CEP16908.1 - 4.6e-07 29.1 0.0 7.3e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP16908.1 - 0.0047 16.6 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CEP16908.1 - 0.067 12.5 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PocR PF10114.4 CEP16908.1 - 0.084 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR PIP49_C PF12260.3 CEP16908.1 - 0.26 10.6 2.7 1 8.7 0.2 2.5 2 1 0 2 2 2 0 Protein-kinase domain of FAM69 Orthopox_35kD PF02250.10 CEP16909.1 - 0.024 13.9 0.8 0.055 12.7 0.5 1.7 1 1 0 1 1 1 0 35kD major secreted virus protein Lactamase_B PF00753.22 CEP16910.1 - 4.7e-23 81.8 3.7 5.9e-23 81.5 2.5 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CEP16910.1 - 1.8e-06 27.6 0.4 2.9e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lum_binding PF00677.12 CEP16912.1 - 2.3e-44 149.1 6.5 3.5e-24 84.4 0.2 2.1 2 0 0 2 2 2 2 Lumazine binding domain F-box PF00646.28 CEP16913.1 - 4.6e-08 32.5 0.3 1.8e-07 30.6 0.2 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEP16913.1 - 5.8e-08 32.3 0.7 2.1e-07 30.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like DUF3760 PF12586.3 CEP16913.1 - 0.087 12.6 0.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) RRM_1 PF00076.17 CEP16914.1 - 6e-19 67.4 0.7 1.2e-12 47.2 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP16914.1 - 9.3e-08 31.9 0.1 3.6e-05 23.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP16914.1 - 1.5e-05 24.7 0.0 0.069 13.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_5 PF07994.7 CEP16915.1 - 1.7e-113 379.0 0.1 2e-113 378.7 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CEP16915.1 - 9.9e-45 150.9 0.2 1.8e-44 150.1 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Myb_DNA-binding PF00249.26 CEP16917.1 - 1.3e-05 25.1 0.0 8.7e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF2407 PF10302.4 CEP16918.1 - 6.6e-05 23.0 0.3 0.00028 21.0 0.0 2.1 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF2782 PF11191.3 CEP16918.1 - 0.56 10.2 2.6 1.9 8.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) DUF3439 PF11921.3 CEP16918.1 - 0.67 9.7 8.7 1.4 8.7 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF1675 PF07897.6 CEP16918.1 - 1.3 8.8 8.1 1.6 8.5 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MotA_ExbB PF01618.11 CEP16919.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Sds3 PF08598.6 CEP16921.1 - 9.7e-19 67.7 9.0 9.7e-19 67.7 6.2 4.9 2 2 0 2 2 2 1 Sds3-like Ribosomal_S28e PF01200.13 CEP16922.1 - 2.5e-34 116.8 1.6 2.7e-34 116.6 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e tRNA-synt_1b PF00579.20 CEP16923.1 - 8.4e-71 238.4 0.0 1.4e-70 237.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) SNF2_N PF00176.18 CEP16924.1 - 1.1e-38 132.7 1.4 1.4e-38 132.3 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP16924.1 - 1.9e-06 27.6 0.1 5e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP16924.1 - 0.051 13.0 0.0 1.3 8.5 0.0 2.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase ASXH PF13919.1 CEP16925.1 - 5.2e-06 26.2 0.6 1.6e-05 24.7 0.4 1.8 1 1 0 1 1 1 1 Asx homology domain WD40 PF00400.27 CEP16926.1 - 9.6e-13 47.4 0.0 0.0016 18.2 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Vps16_N PF04841.8 CEP16926.1 - 0.02 13.4 0.0 0.11 10.9 0.0 2.1 2 0 0 2 2 2 0 Vps16, N-terminal region Tom37_C PF11801.3 CEP16926.1 - 0.057 13.2 0.2 0.057 13.2 0.1 2.4 2 1 1 3 3 3 0 Tom37 C-terminal domain MFS_1 PF07690.11 CEP16927.1 - 1.1e-44 152.6 31.4 1.5e-44 152.1 21.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP16927.1 - 7.7e-17 61.0 5.4 7.7e-17 61.0 3.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TAFH PF07531.9 CEP16927.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 NHR1 homology to TAF Borrelia_P13 PF05628.7 CEP16927.1 - 0.79 9.5 4.7 1.7 8.4 0.1 3.1 3 0 0 3 3 3 0 Borrelia membrane protein P13 PTR2 PF00854.16 CEP16928.1 - 7e-55 186.3 17.0 2.2e-53 181.3 11.8 2.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 CEP16928.1 - 1.6e-05 23.8 25.5 1.6e-05 23.8 17.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.6 CEP16928.1 - 2 8.1 10.2 1.5 8.5 0.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DDE_Tnp_1_7 PF13843.1 CEP16929.1 - 0.022 13.8 0.0 0.025 13.6 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 RVT_1 PF00078.22 CEP16930.1 - 7.9e-21 74.3 0.0 1.5e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP16930.1 - 3.9e-07 30.4 0.0 1.3e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP16930.1 - 9.1e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 CEP16930.1 - 0.0065 16.3 2.5 0.0065 16.3 1.7 2.7 1 1 1 2 2 2 1 Zinc knuckle RVP PF00077.15 CEP16930.1 - 0.15 12.0 0.0 0.42 10.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Presenilin PF01080.12 CEP16932.1 - 0.051 12.4 2.1 0.061 12.1 1.5 1.0 1 0 0 1 1 1 0 Presenilin EF-hand_4 PF12763.2 CEP16933.1 - 2.1e-30 104.5 0.1 2.4e-19 69.0 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CEP16933.1 - 2.7e-07 30.6 0.0 7.6e-06 25.9 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CEP16933.1 - 1.6e-05 23.8 0.0 0.0091 15.2 0.0 3.5 3 0 0 3 3 3 1 EF hand DUF1720 PF08226.6 CEP16933.1 - 0.0014 18.6 11.6 0.0051 16.8 8.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1720) APG6 PF04111.7 CEP16933.1 - 0.0052 15.8 10.8 0.0081 15.2 0.7 2.3 2 0 0 2 2 2 2 Autophagy protein Apg6 EF-hand_6 PF13405.1 CEP16933.1 - 0.0063 16.3 0.1 9.4 6.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CEP16933.1 - 0.022 14.3 0.0 1.1 8.8 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair Microtub_assoc PF07989.6 CEP16933.1 - 0.18 11.6 5.5 4.2 7.2 0.1 3.3 3 0 0 3 3 3 0 Microtubule associated Peptidase_M3 PF01432.15 CEP16934.1 - 3.2e-125 418.7 0.0 4.7e-125 418.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CEP16934.1 - 0.36 10.1 1.0 0.52 9.6 0.7 1.2 1 0 0 1 1 1 0 Peptidase M50B-like PX PF00787.19 CEP16935.1 - 2.5e-23 82.0 1.7 6e-23 80.8 1.2 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CEP16935.1 - 5.9e-05 22.4 6.3 0.00011 21.5 4.4 1.4 1 0 0 1 1 1 1 Vps5 C terminal like ELFV_dehydrog PF00208.16 CEP16936.1 - 5.4e-52 176.7 0.1 1.1e-51 175.8 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CEP16936.1 - 4.4e-25 87.4 0.4 5.4e-18 63.9 0.0 2.7 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 CEP16936.1 - 0.023 14.2 0.0 0.064 12.8 0.0 1.7 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ribosomal_60s PF00428.14 CEP16937.1 - 1.5e-17 63.7 14.7 1.7e-17 63.6 10.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Reo_sigmaC PF04582.7 CEP16938.1 - 0.00084 18.6 0.7 0.00084 18.6 0.5 1.7 2 0 0 2 2 2 1 Reovirus sigma C capsid protein TFR_dimer PF04253.10 CEP16938.1 - 0.028 13.9 0.5 0.14 11.6 0.3 2.3 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain FlaC_arch PF05377.6 CEP16938.1 - 0.029 14.2 2.3 7.5 6.5 0.2 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PhoQ_Sensor PF08918.5 CEP16938.1 - 0.068 12.6 2.0 1.6 8.1 0.0 3.1 3 0 0 3 3 3 0 PhoQ Sensor Spectrin PF00435.16 CEP16938.1 - 0.11 12.7 5.0 5.7 7.2 0.6 3.1 2 1 1 3 3 3 0 Spectrin repeat NPV_P10 PF05531.7 CEP16938.1 - 0.29 11.4 10.5 0.085 13.1 0.8 3.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Sec20 PF03908.8 CEP16938.1 - 1.4 8.6 8.1 4 7.2 0.2 3.6 3 0 0 3 3 3 0 Sec20 Glyco_transf_15 PF01793.11 CEP16939.1 - 1.4e-133 444.9 17.3 1.7e-133 444.6 12.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF1917 PF08939.5 CEP16939.1 - 0.012 15.3 0.1 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) CRAL_TRIO PF00650.15 CEP16940.1 - 3e-29 101.5 0.0 4.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEP16940.1 - 1.2e-05 25.3 0.0 3.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RPAP3_C PF13877.1 CEP16940.1 - 0.055 13.4 0.2 47 4.0 0.0 3.2 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Sec23_trunk PF04811.10 CEP16940.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Ribonuc_red_sm PF00268.16 CEP16941.1 - 5.1e-110 366.9 2.7 6.2e-110 366.6 1.9 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 CEP16942.1 - 1.3e-109 365.6 4.0 1.5e-109 365.3 2.8 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain IMD PF08397.6 CEP16942.1 - 0.11 11.7 0.2 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain Sugar_tr PF00083.19 CEP16943.1 - 1.9e-95 320.0 24.6 2e-48 165.1 9.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP16943.1 - 1.5e-25 89.6 37.8 3.2e-22 78.7 7.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinocilin PF15033.1 CEP16943.1 - 0.052 13.0 1.9 0.15 11.5 1.3 1.8 1 0 0 1 1 1 0 Kinocilin protein Pkinase PF00069.20 CEP16944.1 - 1.6e-61 207.7 0.0 8.9e-61 205.2 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP16944.1 - 7.2e-34 117.0 0.0 9.5e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP16944.1 - 1.6e-05 24.0 0.0 3.7e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP16944.1 - 0.0066 15.5 0.0 0.025 13.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP16944.1 - 0.031 14.0 0.0 0.076 12.7 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.16 CEP16945.1 - 4.6e-09 35.8 0.0 5.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 CEP16946.1 - 3.1e-32 111.3 1.4 4.6e-32 110.8 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Redoxin PF08534.5 CEP16947.1 - 8.9e-31 106.4 0.0 9.9e-31 106.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CEP16947.1 - 2.3e-09 37.0 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Methyltransf_28 PF02636.12 CEP16948.1 - 1.4e-25 90.1 0.0 2.1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RasGAP PF00616.14 CEP16949.1 - 1.2e-54 184.9 0.0 1.2e-54 184.9 0.0 2.9 4 0 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase UPF0220 PF05255.6 CEP16949.1 - 1.6e-43 147.8 1.3 2.8e-43 147.0 0.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RasGAP_C PF03836.10 CEP16949.1 - 6.3e-29 100.4 2.8 6.3e-29 100.4 1.9 2.0 2 0 0 2 2 2 1 RasGAP C-terminus MarR PF01047.17 CEP16949.1 - 0.039 13.6 0.1 11 5.7 0.0 2.8 2 0 0 2 2 2 0 MarR family DUF972 PF06156.8 CEP16949.1 - 1.4 9.2 4.6 4.4 7.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ank_2 PF12796.2 CEP16951.1 - 1.6e-11 44.3 4.1 1.8e-06 28.2 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP16951.1 - 2.6e-10 40.5 1.4 6.3e-07 29.7 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CEP16951.1 - 2.1e-08 33.5 4.7 2e-05 24.1 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CEP16951.1 - 9.3e-08 32.0 5.5 8.4e-05 22.6 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP16951.1 - 8.4e-07 28.6 2.0 0.0012 18.9 0.0 3.2 3 0 0 3 3 2 2 Ankyrin repeat KilA-N PF04383.8 CEP16951.1 - 7.3e-05 22.3 2.6 0.00048 19.7 0.2 3.1 2 2 0 2 2 2 1 KilA-N domain CENP-F_leu_zip PF10473.4 CEP16951.1 - 1.1 9.1 16.0 5.1 6.9 0.6 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 CEP16951.1 - 1.5 8.3 13.0 3 7.3 0.5 2.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V-SNARE PF05008.10 CEP16951.1 - 3.2 7.9 11.8 1.3 9.2 3.5 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.7 CEP16951.1 - 3.4 7.9 11.1 93 3.3 0.1 3.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 CEP16951.1 - 3.5 7.4 8.8 1.6 8.6 2.6 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BHD_3 PF10405.4 CEP16952.1 - 1.4e-24 85.6 0.0 8.3e-24 83.1 0.0 2.4 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CEP16952.1 - 1e-20 73.5 1.6 1e-20 73.5 1.1 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 CEP16952.1 - 4.7e-18 64.4 0.1 1.2e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CEP16952.1 - 2.1e-11 43.9 1.2 8.2e-11 42.0 0.1 2.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CEP16952.1 - 1.7e-06 28.1 0.0 5.4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Daxx PF03344.10 CEP16952.1 - 5.3 5.3 21.9 0.92 7.9 12.4 1.7 2 0 0 2 2 2 0 Daxx Family DUF3321 PF11968.3 CEP16953.1 - 1.4e-39 136.0 0.0 1.9e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CEP16953.1 - 0.038 13.7 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CEP16953.1 - 0.081 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nt_Gln_amidase PF09764.4 CEP16954.1 - 2.7e-45 153.9 0.6 3.4e-45 153.5 0.4 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase Transposase_21 PF02992.9 CEP16955.1 - 1e-06 28.0 0.8 7.3e-06 25.2 0.0 2.2 1 1 1 2 2 2 1 Transposase family tnp2 Cullin_Nedd8 PF10557.4 CEP16956.1 - 0.095 12.5 0.1 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 Cullin protein neddylation domain PIF1 PF05970.9 CEP16961.1 - 2.4e-17 62.9 0.0 6.2e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 CEP16961.1 - 3.4e-15 56.2 0.2 3.4e-15 56.2 0.1 2.3 2 0 0 2 2 1 1 Helitron helicase-like domain at N-terminus UvrD_C_2 PF13538.1 CEP16961.1 - 6.8e-10 39.0 0.0 3e-09 36.9 0.0 2.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEP16961.1 - 7e-05 20.7 0.0 0.15 9.8 0.0 2.3 2 0 0 2 2 2 2 Helicase Viral_helicase1 PF01443.13 CEP16961.1 - 0.00023 20.7 0.2 0.056 12.9 0.1 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CEP16961.1 - 0.00035 20.2 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CEP16961.1 - 0.001 19.1 0.0 0.0045 17.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CEP16961.1 - 0.011 15.9 0.0 0.042 14.0 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 CEP16961.1 - 0.012 15.2 1.7 0.014 14.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CEP16961.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 CEP16961.1 - 0.023 14.6 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 CEP16961.1 - 0.037 13.8 0.0 0.037 13.8 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function DUF87 Transposase_21 PF02992.9 CEP16963.1 - 9.6e-11 41.2 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 C9orf72-like PF15019.1 CEP16965.1 - 0.0088 15.3 0.2 0.0088 15.3 0.2 1.6 2 0 0 2 2 2 1 C9orf72-like protein family Spore_YtrH PF14034.1 CEP16968.1 - 0.11 12.3 0.2 0.24 11.3 0.1 1.6 1 1 1 2 2 2 0 Sporulation protein YtrH Kinesin PF00225.18 CEP16969.1 - 9.3e-101 336.8 0.1 9.3e-101 336.8 0.1 2.4 2 1 0 2 2 2 1 Kinesin motor domain Ras PF00071.17 CEP16971.1 - 3.3e-11 42.8 0.1 0.0001 21.7 0.0 2.4 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CEP16971.1 - 0.00033 21.1 0.0 0.093 13.2 0.0 2.7 1 1 0 2 2 2 2 Miro-like protein Arf PF00025.16 CEP16971.1 - 0.072 12.3 0.1 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Na_H_Exchanger PF00999.16 CEP16972.1 - 7.9e-53 179.3 25.0 1.1e-52 178.8 17.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Neur_chan_memb PF02932.11 CEP16972.1 - 2.2 8.1 7.0 2.8 7.7 3.2 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region YrhC PF14143.1 CEP16972.1 - 8.1 6.4 7.8 0.67 9.9 0.2 2.9 3 0 0 3 3 3 0 YrhC-like protein zf-MYND PF01753.13 CEP16973.1 - 1.1e-06 28.3 20.6 3e-06 26.9 14.3 1.8 1 1 0 1 1 1 1 MYND finger DNA_pol_A_exo1 PF01612.15 CEP16976.1 - 0.00026 20.4 0.1 0.031 13.7 0.0 2.4 1 1 1 2 2 2 2 3'-5' exonuclease DUF572 PF04502.8 CEP16979.1 - 5.8e-28 98.0 7.8 1.1e-27 97.1 5.4 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF1676 PF07898.8 CEP16979.1 - 0.032 14.5 0.2 0.077 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) WD40 PF00400.27 CEP16980.1 - 1.2e-38 129.5 9.2 1.9e-09 37.0 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat Bromodomain PF00439.20 CEP16980.1 - 2.4e-11 43.4 0.1 5.6e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Med31 PF05669.7 CEP16980.1 - 0.03 14.0 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 SOH1 Rib_5-P_isom_A PF06026.9 CEP16981.1 - 1.1e-57 194.1 0.1 1.3e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CEP16981.1 - 8e-05 22.3 0.0 0.0078 15.8 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.8 CEP16981.1 - 0.0095 14.8 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain RibD_C PF01872.12 CEP16982.1 - 1.7e-31 109.4 0.0 1.9e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Linker_histone PF00538.14 CEP16983.1 - 1.1e-19 70.2 0.2 1.1e-19 70.2 0.1 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF4603 PF15376.1 CEP16983.1 - 1.8 5.6 9.6 1.9 5.5 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MbeD_MobD PF04899.7 CEP16984.1 - 0.00088 19.1 8.6 0.49 10.3 0.0 4.6 4 1 1 5 5 5 2 MbeD/MobD like rve PF00665.21 CEP16984.1 - 0.0063 16.6 0.4 0.13 12.3 0.0 2.9 3 0 0 3 3 3 1 Integrase core domain MRFAP1 PF15155.1 CEP16984.1 - 0.1 12.9 1.2 0.86 9.9 0.4 2.5 2 0 0 2 2 2 0 MORF4 family-associated protein1 Snapin_Pallidin PF14712.1 CEP16984.1 - 0.12 12.6 0.1 0.12 12.6 0.1 7.0 4 2 4 8 8 8 0 Snapin/Pallidin PilJ PF13675.1 CEP16984.1 - 1.1 9.6 12.3 0.26 11.6 0.9 4.2 3 2 2 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term GTPase_Cys_C PF12631.2 CEP16984.1 - 1.1 9.6 6.8 4.3 7.8 0.0 4.0 5 0 0 5 5 5 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE MFS_1 PF07690.11 CEP16985.1 - 5e-15 55.0 39.3 5e-15 55.0 27.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily BCHF PF07284.6 CEP16985.1 - 0.067 13.0 5.3 0.09 12.6 0.2 2.6 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Flavi_NS4A PF01350.12 CEP16985.1 - 1.5 8.4 8.8 3.3 7.2 0.3 3.4 2 1 1 3 3 3 0 Flavivirus non-structural protein NS4A Glyco_hydro_71 PF03659.9 CEP16986.1 - 0.0026 16.2 0.3 0.0028 16.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 BRCT PF00533.21 CEP16988.1 - 1.2e-12 47.7 1.2 4.7e-06 26.6 0.0 3.6 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PK_C PF02887.11 CEP16988.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain PilP PF04351.8 CEP16988.1 - 0.53 10.1 4.3 1.3 8.8 3.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilP CPSase_L_D2 PF02786.12 CEP16989.1 - 3.1e-76 255.3 0.1 5.8e-76 254.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CEP16989.1 - 1.6e-42 144.0 0.3 1.6e-42 144.0 0.2 2.5 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CEP16989.1 - 4.3e-35 119.9 0.0 9.4e-35 118.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CEP16989.1 - 3.7e-17 61.7 1.6 1.2e-16 60.0 0.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CEP16989.1 - 4.5e-14 52.5 0.1 1.1e-13 51.3 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEP16989.1 - 1.1e-12 47.4 0.2 1.8e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CEP16989.1 - 3.1e-10 39.7 0.1 7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CEP16989.1 - 6.2e-09 35.3 0.1 1.2e-05 24.8 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 CEP16989.1 - 4.1e-06 26.2 0.5 2.1e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CEP16989.1 - 9.3e-06 25.5 0.1 2.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CEP16989.1 - 9.6e-06 25.8 0.4 0.22 11.9 0.1 3.5 3 0 0 3 3 3 2 HlyD family secretion protein RimK PF08443.6 CEP16989.1 - 7.5e-05 22.2 0.1 0.00023 20.7 0.0 1.8 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 CEP16989.1 - 0.0034 16.9 0.1 0.0063 16.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF3182 PF11379.3 CEP16989.1 - 0.03 13.0 0.0 0.054 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) HlyD PF00529.15 CEP16989.1 - 0.14 11.4 0.7 9.5 5.4 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein polyprenyl_synt PF00348.12 CEP16990.1 - 5.2e-55 186.1 0.0 6.3e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase IBN_N PF03810.14 CEP16990.1 - 0.066 13.1 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain Sel1 PF08238.7 CEP16992.1 - 1.3e-115 375.2 59.3 9.9e-11 41.9 0.0 15.8 15 0 0 15 15 15 14 Sel1 repeat NUC194 PF08163.7 CEP16992.1 - 5.4e-38 130.8 4.8 1.2e-37 129.7 3.3 1.5 1 0 0 1 1 1 1 NUC194 domain TPR_6 PF13174.1 CEP16992.1 - 0.0085 16.4 10.5 0.84 10.2 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat Feld-I_B PF09252.5 CEP16992.1 - 0.012 15.4 0.4 10 6.1 0.0 4.1 4 0 0 4 4 4 0 Allergen Fel d I-B chain HEAT PF02985.17 CEP16992.1 - 0.063 13.3 0.1 12 6.2 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.1 CEP16992.1 - 0.15 12.3 0.1 30 4.9 0.1 4.4 5 1 0 5 5 5 0 HEAT repeats PI3_PI4_kinase PF00454.22 CEP16993.1 - 1.3e-47 162.2 0.0 3.6e-47 160.8 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CEP16993.1 - 5.6e-10 38.4 0.0 2.8e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 FATC domain Ipi1_N PF12333.3 CEP16993.1 - 0.13 12.2 0.7 9 6.3 0.0 3.1 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation YibE_F PF07907.6 CEP16993.1 - 0.35 9.9 0.1 0.59 9.2 0.1 1.2 1 0 0 1 1 1 0 YibE/F-like protein 3-HAO PF06052.7 CEP16994.1 - 3.9e-38 130.2 0.3 4.6e-38 130.0 0.2 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CEP16994.1 - 0.0034 16.8 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain ARD PF03079.9 CEP16994.1 - 0.033 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family RFC1 PF08519.7 CEP16995.1 - 2.7e-48 163.6 0.0 3.4e-45 153.5 0.0 2.6 2 0 0 2 2 2 2 Replication factor RFC1 C terminal domain AAA PF00004.24 CEP16995.1 - 2.1e-12 47.3 0.0 6.1e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 CEP16995.1 - 3.6e-07 30.2 0.0 1.3e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.1 CEP16995.1 - 3.4e-06 27.2 0.0 8.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CEP16995.1 - 4.1e-06 25.7 0.0 9e-06 24.6 0.0 1.6 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CEP16995.1 - 0.00029 19.9 0.0 0.00058 18.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 CEP16995.1 - 0.0012 18.3 0.1 0.0098 15.4 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 CEP16995.1 - 0.0013 19.5 0.2 0.011 16.5 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CEP16995.1 - 0.0032 17.3 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP16995.1 - 0.0046 17.2 0.0 0.0046 17.2 0.0 2.6 2 1 1 3 3 1 1 AAA domain NACHT PF05729.7 CEP16995.1 - 0.011 15.4 0.0 0.04 13.5 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 CEP16995.1 - 0.017 14.8 0.0 0.017 14.8 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_16 PF13191.1 CEP16995.1 - 0.017 15.0 0.0 0.098 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 CEP16995.1 - 0.018 13.9 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 CEP16995.1 - 0.024 14.5 0.0 0.075 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CEP16995.1 - 0.051 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NDK PF00334.14 CEP16996.1 - 5.6e-54 181.5 0.0 6.7e-54 181.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 CEP16996.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ DDE_3 PF13358.1 CEP16997.1 - 3.2e-30 104.8 0.0 5.4e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP16997.1 - 1.7e-08 34.6 0.0 3.8e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP16997.1 - 3.3e-08 33.3 1.6 4.1e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP16997.1 - 3.4e-07 30.9 0.0 1.2e-06 29.1 0.0 2.1 2 0 0 2 2 1 1 Homeodomain-like domain HTH_23 PF13384.1 CEP16997.1 - 5.7e-07 28.9 0.3 1.7e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.2 CEP16997.1 - 0.00038 20.6 0.4 0.49 10.6 0.0 2.7 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_7 PF02796.10 CEP16997.1 - 0.0057 16.4 0.1 3.6 7.5 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase Terminase_5 PF06056.7 CEP16997.1 - 0.0094 15.4 1.6 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) DUF1804 PF08822.6 CEP16997.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) HTH_Tnp_1 PF01527.15 CEP16997.1 - 0.033 14.1 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Transposase RepA_N PF06970.6 CEP16997.1 - 0.053 13.3 1.6 5.1 6.9 0.0 2.8 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus TrmB PF01978.14 CEP16997.1 - 0.084 12.5 0.1 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF3625 PF12293.3 CEP16997.1 - 0.094 11.8 0.0 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3625) Mito_carr PF00153.22 CEP16998.1 - 2.5e-54 180.9 8.6 5.4e-21 74.0 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein EHN PF06441.7 CEP17000.1 - 3.9e-26 91.1 3.9 3.9e-26 91.1 2.7 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CEP17000.1 - 2.3e-17 63.6 0.0 3.6e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP17000.1 - 2.3e-12 46.9 0.0 5.3e-12 45.8 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF3824 PF12868.2 CEP17001.1 - 0.0093 16.8 1.9 0.0093 16.8 1.3 2.5 2 0 0 2 2 2 1 Domain of unknwon function (DUF3824) Peptidase_S49_N PF08496.5 CEP17001.1 - 0.057 13.1 16.2 0.35 10.6 1.8 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.6 CEP17001.1 - 7.6 6.1 35.4 0.74 9.4 10.2 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Tyr-DNA_phospho PF06087.7 CEP17002.1 - 1e-88 297.9 1.2 8.2e-87 291.6 0.8 2.0 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Esterase PF00756.15 CEP17003.1 - 4.5e-60 203.1 0.0 5.3e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 CEP17003.1 - 6.4e-08 32.0 0.0 8.7e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEP17003.1 - 7.8e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CEP17003.1 - 8.4e-05 21.5 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.4 CEP17003.1 - 0.0007 18.9 0.0 0.0055 15.9 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase PF07224.6 CEP17003.1 - 0.0031 16.3 0.0 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase PAF-AH_p_II PF03403.8 CEP17003.1 - 0.0058 14.9 0.0 0.009 14.3 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 CEP17003.1 - 0.017 14.7 0.1 0.029 14.0 0.1 1.4 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 CEP17003.1 - 0.022 14.6 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CEP17003.1 - 0.026 13.9 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CEP17003.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 CEP17003.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S15 PF02129.13 CEP17003.1 - 0.1 11.9 0.0 1 8.7 0.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3245 PF11595.3 CEP17004.1 - 1.3e-10 41.7 2.5 2.2e-10 40.9 1.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) G-patch_2 PF12656.2 CEP17004.1 - 0.052 13.3 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site Rap_GAP PF02145.10 CEP17005.1 - 5.7e-53 179.0 0.0 2.1e-52 177.2 0.0 2.0 2 0 0 2 2 2 1 Rap/ran-GAP Lzipper-MIP1 PF14389.1 CEP17007.1 - 0.011 15.8 0.1 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF1192 PF06698.6 CEP17007.1 - 0.021 14.6 3.9 0.045 13.5 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) eIF3_subunit PF08597.5 CEP17008.1 - 3e-42 144.8 28.8 3e-42 144.8 19.9 2.5 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit IL22 PF14565.1 CEP17008.1 - 0.017 15.1 2.6 0.13 12.3 1.6 2.3 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor DUF1664 PF07889.7 CEP17008.1 - 0.52 10.1 7.9 1.7 8.4 5.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Noelin-1 PF12308.3 CEP17008.1 - 1.5 8.6 9.5 0.5 10.1 3.4 2.4 1 1 1 2 2 2 0 Neurogenesis glycoprotein Dak1 PF02733.12 CEP17010.1 - 4.2e-114 380.4 3.0 5.9e-114 380.0 2.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CEP17010.1 - 8.7e-40 136.2 0.2 1.5e-39 135.4 0.1 1.4 1 0 0 1 1 1 1 DAK2 domain Cyclin PF08613.6 CEP17011.1 - 5.4e-16 59.3 2.8 7.5e-14 52.3 2.0 2.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP17011.1 - 0.0062 16.0 0.0 0.0062 16.0 0.0 2.5 2 1 1 3 3 3 1 Cyclin, N-terminal domain DUF853 PF05872.7 CEP17011.1 - 0.032 12.5 0.8 2.1 6.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Aminotran_1_2 PF00155.16 CEP17012.1 - 9.8e-86 287.9 0.0 1.1e-85 287.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TIG PF01833.19 CEP17013.1 - 2e-12 46.9 0.2 2e-12 46.9 0.2 3.6 5 0 0 5 5 5 1 IPT/TIG domain Ank_4 PF13637.1 CEP17013.1 - 0.0017 18.8 0.2 0.0084 16.6 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP17013.1 - 0.0045 17.1 0.4 0.063 13.5 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP17013.1 - 0.019 15.1 0.4 2.7 8.4 0.1 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.2 CEP17013.1 - 0.034 14.4 0.0 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.25 CEP17013.1 - 0.32 10.9 1.5 5.3 7.0 0.1 2.9 2 1 1 3 3 3 0 Ankyrin repeat Sel1 PF08238.7 CEP17014.1 - 2.3e-42 142.4 28.6 9.3e-10 38.8 0.4 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_11 PF13414.1 CEP17014.1 - 2.6e-07 30.1 24.6 0.06 13.0 2.5 5.2 3 2 2 5 5 5 4 TPR repeat TPR_7 PF13176.1 CEP17014.1 - 0.00028 20.4 9.7 3.8 7.5 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP17014.1 - 0.065 13.8 6.1 1.6 9.5 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP17014.1 - 1.9 9.1 10.2 4.2 8.0 0.3 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEP17014.1 - 2.3 8.9 14.2 16 6.3 1.4 4.5 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP17014.1 - 4.5 7.4 28.1 9.9 6.3 0.1 8.5 9 1 1 10 10 10 0 Tetratricopeptide repeat Ank_2 PF12796.2 CEP17015.1 - 0.00043 20.5 0.0 0.0052 17.0 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP17015.1 - 0.01 16.0 0.1 0.061 13.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PH PF00169.24 CEP17015.1 - 0.012 15.8 0.2 0.012 15.8 0.1 3.6 3 1 0 3 3 3 0 PH domain Ank PF00023.25 CEP17015.1 - 0.013 15.2 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 CEP17015.1 - 0.059 13.9 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DDE_3 PF13358.1 CEP17016.1 - 0.0048 16.6 0.0 0.0062 16.2 0.0 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_64 PF09258.5 CEP17017.1 - 6.3e-50 169.6 0.1 9.8e-50 169.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.15 CEP17017.1 - 0.00076 18.8 0.3 0.00076 18.8 0.2 2.7 2 1 1 3 3 3 1 Glycosyl transferase family 8 LuxS PF02664.10 CEP17017.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) TPR_11 PF13414.1 CEP17018.1 - 4.7e-58 192.7 26.6 4.3e-15 55.1 1.6 8.2 3 3 5 8 8 8 8 TPR repeat TPR_1 PF00515.23 CEP17018.1 - 6e-44 145.9 26.9 1.8e-05 24.1 0.0 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 CEP17018.1 - 1.2e-42 140.3 20.2 6.7e-05 22.5 0.0 12.0 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_16 PF13432.1 CEP17018.1 - 1.6e-31 108.2 4.7 4.9e-06 27.0 0.1 6.6 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 CEP17018.1 - 2.9e-27 92.5 13.7 0.0021 18.1 0.0 10.1 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 CEP17018.1 - 1.8e-24 85.4 21.6 1.6e-06 27.9 0.3 7.9 3 3 6 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 CEP17018.1 - 2.8e-23 79.8 29.6 0.053 13.3 0.4 12.0 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.1 CEP17018.1 - 8e-22 75.7 4.9 0.013 16.1 0.4 9.6 3 3 7 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 CEP17018.1 - 3.2e-21 75.4 15.7 1.4e-06 28.4 1.0 7.5 5 3 2 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 CEP17018.1 - 1.6e-13 50.3 2.4 0.0012 18.6 0.0 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 CEP17018.1 - 4.1e-12 44.9 12.5 0.012 15.3 0.3 9.3 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP17018.1 - 3.7e-10 39.7 14.9 0.0038 17.3 0.2 5.6 3 2 5 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CEP17018.1 - 2.2e-07 30.2 1.8 0.16 10.9 0.0 4.9 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CEP17018.1 - 4.6e-07 29.8 23.2 0.64 10.6 0.1 9.7 11 0 0 11 11 10 2 Tetratricopeptide repeat NARP1 PF12569.3 CEP17018.1 - 3.7e-06 25.9 18.6 0.00099 17.9 0.0 5.3 2 2 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 CEP17018.1 - 0.00033 20.7 9.9 0.36 10.9 0.0 5.7 5 1 1 6 6 5 1 Tetratricopeptide repeat DUF3856 PF12968.2 CEP17018.1 - 0.0026 17.5 9.9 8.8 6.1 0.0 5.4 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.1 CEP17018.1 - 0.0064 16.3 12.2 0.58 10.1 0.5 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 CEP17018.1 - 0.015 15.6 0.0 2.3 8.9 0.1 4.5 5 0 0 5 5 2 0 Tetratricopeptide repeat DUF357 PF04010.8 CEP17018.1 - 0.016 14.8 3.6 0.21 11.3 0.0 4.0 4 0 0 4 4 3 0 Protein of unknown function (DUF357) Mucin PF01456.12 CEP17018.1 - 0.023 14.4 20.0 0.043 13.5 13.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein BTAD PF03704.12 CEP17018.1 - 0.056 13.7 5.9 0.77 10.0 0.7 3.6 3 1 0 3 3 3 0 Bacterial transcriptional activator domain SpoIIIAH PF12685.2 CEP17018.1 - 0.087 12.3 8.0 0.18 11.3 5.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein SHNi-TPR PF10516.4 CEP17018.1 - 0.31 10.3 3.4 0.37 10.0 0.0 2.9 4 0 0 4 4 4 0 SHNi-TPR DUF3439 PF11921.3 CEP17018.1 - 2.5 7.8 8.8 5.2 6.8 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DDE_3 PF13358.1 CEP17019.1 - 1.3e-05 25.0 1.0 0.0036 17.0 0.1 2.5 2 1 1 3 3 3 2 DDE superfamily endonuclease DUF2363 PF10155.4 CEP17021.1 - 2.7e-25 88.7 1.8 4.2e-25 88.1 1.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) AMP-binding PF00501.23 CEP17022.1 - 5.8e-91 304.9 0.0 9.2e-75 251.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CEP17022.1 - 1.2e-22 80.5 0.1 2.3e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 CEP17022.1 - 1.2e-05 25.2 0.1 9e-05 22.4 0.0 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Ribosomal_L5_C PF00673.16 CEP17023.1 - 4.1e-24 84.1 0.0 5.9e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CEP17023.1 - 5.3e-19 67.7 0.1 1.5e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 BAG PF02179.11 CEP17025.1 - 5.1e-10 39.3 1.7 5.1e-10 39.3 1.2 1.8 2 0 0 2 2 2 1 BAG domain Ubiquitin_2 PF14560.1 CEP17025.1 - 7.6e-06 26.0 0.0 2.1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 CEP17025.1 - 1.2e-05 24.5 0.0 0.00016 20.9 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family FliX PF10768.4 CEP17025.1 - 0.075 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Class II flagellar assembly regulator Adeno_E4 PF05385.6 CEP17025.1 - 0.32 10.9 1.5 1.5 8.8 0.7 2.3 2 1 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein AA_permease_2 PF13520.1 CEP17026.1 - 2.5e-61 207.5 56.2 3e-61 207.2 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP17026.1 - 3.2e-34 118.0 45.8 4.5e-34 117.6 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.6 CEP17026.1 - 1.2 8.0 5.6 0.41 9.5 1.0 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2353 PF09789.4 CEP17027.1 - 0.012 14.8 0.5 0.013 14.7 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) RIB43A PF05914.7 CEP17027.1 - 0.026 13.1 2.2 0.031 12.9 1.5 1.0 1 0 0 1 1 1 0 RIB43A Hrs_helical PF12210.3 CEP17027.1 - 0.041 14.1 0.7 0.045 13.9 0.5 1.1 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate LURAP PF14854.1 CEP17027.1 - 0.13 12.0 0.6 0.17 11.6 0.4 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF3772 PF12607.3 CEP17027.1 - 1.6 8.4 5.3 2 8.1 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3772) Pkinase PF00069.20 CEP17028.1 - 4.5e-77 258.7 0.0 5.1e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17028.1 - 1.5e-36 125.7 0.0 2.3e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP17028.1 - 0.027 13.4 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CEP17028.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cpn60_TCP1 PF00118.19 CEP17029.1 - 2e-152 508.2 0.4 2.3e-152 508.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myb_DNA-bind_5 PF13873.1 CEP17030.1 - 0.0001 22.1 0.5 0.0002 21.1 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CEP17030.1 - 0.00046 20.2 0.9 0.00064 19.8 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CEP17030.1 - 0.0011 19.5 4.0 0.027 15.1 0.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain AMP-binding PF00501.23 CEP17031.1 - 6.4e-72 242.2 0.1 9e-72 241.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP17031.1 - 5.7e-10 40.0 0.3 1.3e-09 38.8 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.16 CEP17032.1 - 2.8e-06 27.1 0.0 0.00029 20.5 0.0 2.2 1 1 0 2 2 2 2 Peptidase M16 inactive domain EntA_Immun PF08951.5 CEP17032.1 - 0.99 9.6 4.4 2 8.5 0.2 2.7 2 1 1 3 3 3 0 Enterocin A Immunity Sec7 PF01369.15 CEP17034.1 - 2.4e-41 141.5 0.6 5.4e-41 140.3 0.4 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CEP17034.1 - 5.5e-35 120.1 0.0 2.2e-34 118.1 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEP17034.1 - 0.00027 21.0 0.0 0.00088 19.4 0.0 1.9 1 0 0 1 1 1 1 PH domain YCII PF03795.9 CEP17034.1 - 0.075 13.2 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 YCII-related domain CTP_synth_N PF06418.9 CEP17035.1 - 1.5e-121 404.7 0.1 2e-121 404.3 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CEP17035.1 - 3.5e-56 189.6 0.0 5.8e-56 188.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CEP17035.1 - 2.4e-08 33.7 0.0 5.6e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 CEP17035.1 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain HMG_box PF00505.14 CEP17036.1 - 1.8e-17 63.3 1.6 3.8e-17 62.3 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP17036.1 - 4.7e-08 33.2 0.7 1.2e-07 32.0 0.5 1.7 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.9 CEP17036.1 - 0.053 13.2 0.2 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV HEM4 PF02602.10 CEP17037.1 - 5.7e-35 120.6 0.0 6.7e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF3110 PF11360.3 CEP17037.1 - 0.019 14.7 0.1 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) rpo132 PF12415.3 CEP17037.1 - 0.099 11.6 0.2 8.1 5.4 0.0 2.6 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase p450 PF00067.17 CEP17038.1 - 9.2e-41 139.8 0.4 1.1e-40 139.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1_DerP2_DerF2 PF02221.10 CEP17040.1 - 4.9e-21 75.3 0.8 6.3e-21 75.0 0.5 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CEP17040.1 - 0.0057 16.6 0.1 0.014 15.4 0.1 1.7 1 1 0 1 1 1 1 ML-like domain TOBE_2 PF08402.5 CEP17040.1 - 0.053 13.5 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 TOBE domain Alpha-amyl_C2 PF07821.7 CEP17040.1 - 0.087 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain EF-hand_4 PF12763.2 CEP17041.1 - 5.2e-37 125.7 1.5 8.8e-13 47.8 0.0 4.4 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CEP17041.1 - 1.2e-15 55.5 1.8 0.0051 16.0 0.0 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 CEP17041.1 - 1.4e-13 50.7 2.5 3.1e-05 24.0 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CEP17041.1 - 2.4e-10 39.3 1.8 0.97 9.5 0.0 5.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 CEP17041.1 - 2.4e-09 36.6 0.1 0.19 11.3 0.0 5.1 4 1 1 5 5 5 3 EF-hand domain pair ATG16 PF08614.6 CEP17041.1 - 0.00034 20.5 17.2 0.00034 20.5 11.9 2.2 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) EF-hand_5 PF13202.1 CEP17041.1 - 0.014 14.7 1.3 1.1 8.7 0.0 3.4 4 0 0 4 4 4 0 EF hand Nse4_C PF08743.5 CEP17041.1 - 0.076 13.0 0.8 0.24 11.4 0.5 1.9 1 0 0 1 1 1 0 Nse4 C-terminal BBS2_C PF14782.1 CEP17041.1 - 0.26 9.8 9.1 0.41 9.1 6.3 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal V_ATPase_I PF01496.14 CEP17041.1 - 1.8 6.2 7.0 2.9 5.6 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CEP17041.1 - 1.9 7.4 19.4 3.5 6.5 13.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 rve PF00665.21 CEP17043.1 - 8.8e-09 35.5 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP17043.1 - 1.8e-06 27.3 0.0 4.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF2666 PF10869.3 CEP17043.1 - 0.024 14.6 1.4 0.043 13.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Retrotrans_gag PF03732.12 CEP17044.1 - 3.4e-06 27.0 0.1 0.0026 17.7 0.0 3.0 2 1 0 2 2 2 2 Retrotransposon gag protein zf-CCHC PF00098.18 CEP17044.1 - 0.00021 21.0 6.0 0.00047 19.9 4.2 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 CEP17044.1 - 0.00042 19.7 0.0 0.028 13.7 0.0 3.1 2 1 2 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CEP17044.1 - 0.012 15.4 0.1 2.5 7.9 0.0 2.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CEP17044.1 - 0.012 15.6 0.0 0.065 13.1 0.1 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEP17044.1 - 0.018 15.5 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease PIF1 PF05970.9 CEP17045.1 - 1.1e-33 116.6 0.9 4.5e-27 94.9 0.0 2.5 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 CEP17045.1 - 9.1e-23 80.9 0.1 2.6e-22 79.4 0.1 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 CEP17045.1 - 6.9e-13 48.6 0.0 3.9e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP17045.1 - 2.6e-07 30.2 0.1 1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 CEP17045.1 - 3.1e-07 30.4 0.1 1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Exo_endo_phos PF03372.18 CEP17045.1 - 2.4e-06 27.6 0.0 6.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Viral_helicase1 PF01443.13 CEP17045.1 - 3.5e-05 23.4 1.5 0.0038 16.7 0.1 3.3 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CEP17045.1 - 4.7e-05 23.5 0.0 0.00036 20.6 0.0 2.6 2 0 0 2 2 1 1 AAA domain Exo_endo_phos_2 PF14529.1 CEP17045.1 - 0.00013 21.6 0.1 0.00039 20.0 0.1 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AAA_11 PF13086.1 CEP17045.1 - 0.0011 18.5 0.2 0.52 9.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CEP17045.1 - 0.041 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain MDMPI_N PF11716.3 CEP17046.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.7 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Exo_endo_phos_2 PF14529.1 CEP17048.1 - 3.3e-09 36.3 0.1 5.4e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP17048.1 - 2e-06 27.9 0.5 2.5e-06 27.6 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CENP-Q PF13094.1 CEP17049.1 - 0.00081 19.4 14.3 0.0025 17.8 9.9 1.7 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 CEP17049.1 - 0.11 12.1 8.4 0.057 13.0 3.8 2.0 2 0 0 2 2 2 0 IncA protein Zn_Tnp_IS1595 PF12760.2 CEP17049.1 - 0.39 10.5 6.6 1.5 8.7 0.8 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 CEP17049.1 - 0.49 10.7 3.5 2.4 8.6 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double domain DUF3573 PF12097.3 CEP17049.1 - 0.86 8.1 12.4 1.7 7.1 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PHD PF00628.24 CEP17049.1 - 1.2 8.8 6.9 9.5 6.0 0.3 2.7 2 0 0 2 2 2 0 PHD-finger zf-CHY PF05495.7 CEP17049.1 - 7.6 6.7 9.9 21 5.3 0.5 3.0 2 1 0 2 2 2 0 CHY zinc finger RVT_1 PF00078.22 CEP17050.1 - 3.4e-21 75.6 0.0 6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP17050.1 - 2.8e-08 33.3 0.2 7.9e-08 31.9 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP17050.1 - 1.1e-05 25.4 0.6 2.5e-05 24.3 0.3 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PMBR PF09373.5 CEP17050.1 - 0.36 10.8 1.6 3.3 7.8 0.2 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat zf-CCHC PF00098.18 CEP17051.1 - 1.1e-05 25.1 2.7 1.4e-05 24.8 0.7 2.0 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.1 CEP17051.1 - 1.1e-05 25.7 0.1 2.6e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CEP17051.1 - 9.3e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 CEP17051.1 - 0.0017 17.9 0.2 0.0035 16.9 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP17051.1 - 0.0071 16.2 0.0 0.03 14.2 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 CEP17052.1 - 1.6e-16 60.3 0.0 4.5e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 CEP17052.1 - 6.9e-07 28.5 0.7 2.6e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger rve PF00665.21 CEP17052.1 - 1.1e-05 25.5 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain IBV_3C PF03620.8 CEP17052.1 - 0.17 11.8 1.3 5.9 6.8 0.1 2.9 2 0 0 2 2 2 0 IBV 3C protein zf-RVT PF13966.1 CEP17053.1 - 0.0002 21.6 0.6 0.0002 21.6 0.4 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-RVT PF13966.1 CEP17054.1 - 0.00012 22.3 1.5 0.00025 21.2 1.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MRG PF05712.8 CEP17054.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 MRG RVT_1 PF00078.22 CEP17054.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CEP17055.1 - 0.002 17.9 5.1 0.002 17.9 3.6 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CHC2 PF01807.15 CEP17055.1 - 0.057 12.9 0.8 0.099 12.2 0.1 1.6 1 1 0 1 1 1 0 CHC2 zinc finger zf-CCHC_4 PF14392.1 CEP17055.1 - 0.26 10.9 14.2 0.38 10.4 1.4 2.4 1 1 1 2 2 2 0 Zinc knuckle YL1 PF05764.8 CEP17055.1 - 4.2 6.9 14.5 6.5 6.2 10.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein zf-CCHC_2 PF13696.1 CEP17055.1 - 9.6 5.7 19.2 5.1 6.6 2.6 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 CEP17056.1 - 2.2e-06 27.3 13.1 0.0011 18.7 1.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CEP17056.1 - 0.0026 17.3 8.0 0.2 11.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CEP17056.1 - 0.028 13.9 5.6 0.028 13.9 3.9 2.5 1 1 1 2 2 2 0 Zinc knuckle FAD_binding_1 PF00667.15 CEP17059.1 - 0.11 11.8 0.1 0.33 10.3 0.0 1.7 1 1 1 2 2 2 0 FAD binding domain DUF4218 PF13960.1 CEP17061.1 - 7.8e-09 35.0 1.5 1.3e-08 34.3 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF3808 PF10300.4 CEP17065.1 - 7e-56 189.7 2.0 1.4e-55 188.7 0.9 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 CEP17065.1 - 0.044 13.7 2.1 30 4.8 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyclin_N PF00134.18 CEP17066.1 - 3.9e-22 78.1 2.1 3e-20 72.0 0.4 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 CEP17066.1 - 3.4e-06 26.7 0.0 0.00076 19.2 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.14 CEP17066.1 - 5.2e-05 23.1 2.1 0.0044 16.9 0.2 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain Myosin_head PF00063.16 CEP17067.1 - 1.4e-250 833.1 0.8 1.4e-250 833.1 0.5 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CEP17067.1 - 2.1e-30 104.6 1.4 2.1e-30 104.6 1.0 2.6 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 CEP17067.1 - 9.1e-13 46.6 45.0 1.4e-05 24.2 1.1 7.0 7 0 0 7 7 7 4 IQ calmodulin-binding motif Lzipper-MIP1 PF14389.1 CEP17067.1 - 0.0018 18.3 11.2 0.0053 16.8 0.9 3.4 2 1 1 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 AAA_22 PF13401.1 CEP17067.1 - 0.009 16.1 0.0 0.057 13.5 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CEP17067.1 - 0.02 14.3 4.1 0.12 11.7 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain Myosin_N PF02736.14 CEP17067.1 - 0.035 13.7 0.6 0.11 12.2 0.4 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 CEP17067.1 - 0.057 13.1 0.0 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Reo_sigmaC PF04582.7 CEP17067.1 - 2.2 7.3 6.8 0.94 8.5 2.3 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TSC22 PF01166.13 CEP17067.1 - 2.5 8.1 12.5 0.24 11.4 0.9 4.3 3 1 1 4 4 4 0 TSC-22/dip/bun family Peptidase_S8 PF00082.17 CEP17068.1 - 9.3e-41 139.8 6.1 1.4e-40 139.2 4.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CEP17068.1 - 0.0015 19.0 0.2 0.003 18.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 OrfB_Zn_ribbon PF07282.6 CEP17069.1 - 0.00058 19.4 0.8 0.0012 18.3 0.0 2.0 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Chordopox_A13L PF05961.6 CEP17069.1 - 0.013 15.4 0.8 0.63 10.0 0.2 3.3 3 0 0 3 3 3 0 Chordopoxvirus A13L protein TraG_N PF07916.6 CEP17069.1 - 0.11 10.8 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region YbjQ_1 PF01906.12 CEP17070.1 - 0.048 14.0 0.1 0.15 12.4 0.0 1.7 1 1 1 2 2 2 0 Putative heavy-metal-binding DUF2881 PF11087.3 CEP17072.1 - 0.41 10.1 5.4 0.1 12.1 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2881) FH2 PF02181.18 CEP17073.1 - 3.1e-67 227.0 31.2 2.7e-47 161.4 2.0 4.1 3 1 1 4 4 4 3 Formin Homology 2 Domain Drf_FH3 PF06367.11 CEP17073.1 - 3.2e-22 78.9 0.1 3.2e-22 78.9 0.0 3.6 4 1 1 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 CEP17073.1 - 3.4e-20 72.2 0.1 3.4e-20 72.2 0.1 2.6 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain rve PF00665.21 CEP17075.1 - 8.1e-16 58.2 0.0 4.2e-14 52.6 0.0 3.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CEP17075.1 - 2.1e-09 36.8 2.0 5.1e-09 35.6 1.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 CEP17075.1 - 3.8e-05 23.5 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CEP17075.1 - 0.0016 18.4 0.3 0.0068 16.4 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CEP17075.1 - 0.032 14.7 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Tcp11 PF05794.8 CEP17077.1 - 8.2e-77 258.7 12.2 8.2e-77 258.7 8.4 2.4 3 0 0 3 3 3 1 T-complex protein 11 PfkB PF00294.19 CEP17078.1 - 3.4e-22 78.9 0.1 4.1e-16 58.9 0.0 2.2 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Dus PF01207.12 CEP17078.1 - 0.022 13.6 0.2 0.056 12.2 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) NinB PF05772.7 CEP17078.1 - 0.076 12.6 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 NinB protein Inhibitor_I36 PF03995.8 CEP17078.1 - 0.1 12.9 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor family I36 DUF4551 PF15087.1 CEP17079.1 - 1.3 7.3 4.2 1.1 7.5 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) GATA PF00320.22 CEP17080.1 - 4.9e-15 54.5 5.5 4.9e-15 54.5 3.8 2.1 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CEP17080.1 - 0.0011 18.1 2.2 0.0022 17.3 1.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Peptidase_S10 PF00450.17 CEP17081.1 - 3e-52 178.1 6.7 3.7e-31 108.7 0.6 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase HSF_DNA-bind PF00447.12 CEP17084.1 - 0.00034 20.7 6.3 0.00035 20.6 0.0 3.3 2 1 1 3 3 3 1 HSF-type DNA-binding DUF3959 PF13105.1 CEP17084.1 - 0.46 9.7 4.9 0.79 8.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) SRP54 PF00448.17 CEP17085.1 - 1e-76 256.7 1.9 1e-76 256.7 1.3 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CEP17085.1 - 3.3e-27 94.7 4.0 3.3e-27 94.7 2.8 5.4 2 1 3 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 CEP17085.1 - 3.6e-16 59.0 2.3 9.3e-16 57.7 1.6 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CEP17085.1 - 5.8e-09 35.6 0.1 1.8e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CEP17085.1 - 2.9e-05 23.7 0.0 9.9e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CEP17085.1 - 3e-05 23.9 0.0 6.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 CEP17085.1 - 5.9e-05 22.5 0.6 0.00039 19.8 0.2 2.5 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CEP17085.1 - 0.001 17.9 1.1 0.013 14.2 0.2 2.7 2 1 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 CEP17085.1 - 0.0015 19.3 0.0 0.0053 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 CEP17085.1 - 0.0016 17.7 0.1 0.26 10.4 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 CEP17085.1 - 0.0028 16.7 0.0 0.0061 15.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.1 CEP17085.1 - 0.0058 16.2 0.0 0.017 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF3418 PF11898.3 CEP17085.1 - 0.0082 14.5 0.0 0.013 13.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) ATP_bind_1 PF03029.12 CEP17085.1 - 0.013 15.0 0.8 0.11 11.9 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 CEP17085.1 - 0.014 15.1 0.0 0.05 13.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Thymidylate_kin PF02223.12 CEP17085.1 - 0.018 14.4 0.0 0.14 11.5 0.1 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.1 CEP17085.1 - 0.021 14.9 0.1 0.097 12.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_31 PF13614.1 CEP17085.1 - 0.023 14.6 0.0 14 5.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF4618 PF15397.1 CEP17085.1 - 0.029 13.7 2.2 0.071 12.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) AAA_10 PF12846.2 CEP17085.1 - 0.039 13.4 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 CEP17085.1 - 0.041 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 CEP17085.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain YlbD_coat PF14071.1 CEP17085.1 - 0.42 10.6 8.0 3.4 7.7 0.7 3.2 1 1 1 2 2 2 0 Putative coat protein AAA PF00004.24 CEP17085.1 - 0.5 10.5 4.0 0.69 10.1 0.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Oxysterol_BP PF01237.13 CEP17086.1 - 8.1e-78 261.3 2.4 9.2e-78 261.2 1.7 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein AAA_assoc PF14363.1 CEP17087.1 - 0.097 12.7 0.6 9.9 6.2 0.0 2.9 3 0 0 3 3 3 0 Domain associated at C-terminal with AAA DEAD PF00270.24 CEP17088.1 - 2.5e-16 59.6 0.0 5.7e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP17088.1 - 1.7e-15 56.6 0.1 7.2e-14 51.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP17088.1 - 5.4e-06 26.3 0.1 1.1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RQC PF09382.5 CEP17088.1 - 6.4e-06 25.8 0.0 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 RQC domain Osmo_CC PF08946.5 CEP17088.1 - 0.0091 16.0 2.3 0.032 14.2 1.6 2.0 1 0 0 1 1 1 1 Osmosensory transporter coiled coil SNF2_N PF00176.18 CEP17088.1 - 0.029 13.1 0.0 0.042 12.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Homeobox PF00046.24 CEP17089.1 - 6.4e-20 70.5 1.2 1.5e-19 69.3 0.8 1.7 1 0 0 1 1 1 1 Homeobox domain Apt1 PF10351.4 CEP17090.1 - 2e-69 234.6 8.2 2e-69 234.6 5.7 2.8 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 CEP17090.1 - 2.3e-57 194.4 6.6 2.3e-57 194.4 4.6 2.1 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 CEP17090.1 - 4.6e-34 117.6 0.0 1.7e-33 115.7 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CEP17090.1 - 6.7e-29 100.6 7.6 8.7e-27 93.7 0.2 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CEP17090.1 - 6.5e-07 29.7 3.4 1.5e-05 25.3 0.0 4.0 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain DNA_pol_E_B PF04042.11 CEP17091.1 - 1.1e-46 158.7 0.2 2e-46 157.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Cyt-b5 PF00173.23 CEP17091.1 - 1.5e-20 72.7 0.3 4.4e-20 71.2 0.2 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CEP17091.1 - 2.3e-08 34.4 20.6 2.3e-08 34.4 14.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Dpoe2NT PF12213.3 CEP17091.1 - 0.0081 16.0 0.2 0.031 14.2 0.1 2.1 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal Abi PF02517.11 CEP17091.1 - 0.7 10.0 4.8 1.5 8.9 3.3 1.5 1 0 0 1 1 1 0 CAAX protease self-immunity Lactamase_B_2 PF12706.2 CEP17092.1 - 4.9e-20 71.9 0.0 1.2e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEP17092.1 - 2e-10 40.6 0.0 4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 CEP17092.1 - 3.3e-07 29.6 0.0 7.6e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Thiolase_N PF00108.18 CEP17093.1 - 3e-102 341.1 1.4 4.3e-102 340.6 1.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEP17093.1 - 2.3e-44 149.7 0.5 2.3e-44 149.7 0.4 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CEP17093.1 - 7.7e-06 25.5 1.2 1.9e-05 24.2 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CEP17093.1 - 0.5 10.0 3.5 5.5 6.7 0.1 3.2 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CTD_bind PF04818.8 CEP17095.1 - 1.4e-08 34.8 0.1 3.9e-08 33.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Glyco_transf_15 PF01793.11 CEP17096.1 - 1.6e-129 431.6 8.8 1.6e-129 431.6 6.1 2.1 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase Myb_DNA-binding PF00249.26 CEP17096.1 - 7.7e-41 137.9 17.1 2.7e-14 52.9 1.0 5.6 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP17096.1 - 7.1e-35 118.9 15.8 1.9e-14 53.5 1.3 4.7 2 1 2 4 4 4 4 Myb-like DNA-binding domain U-box PF04564.10 CEP17099.1 - 6.9e-22 77.1 0.0 1.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 CEP17099.1 - 2.7e-20 71.7 5.4 6.3e-17 60.9 0.1 3.3 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 CEP17099.1 - 2e-13 49.3 8.5 2e-08 33.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP17099.1 - 2.6e-11 42.5 8.0 0.0012 18.6 0.0 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEP17099.1 - 2.9e-07 30.3 2.5 2.3e-06 27.4 0.4 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CEP17099.1 - 2.3e-06 27.6 1.6 2.3e-06 27.6 1.1 1.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CEP17099.1 - 4.2e-06 26.5 0.4 0.068 13.4 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP17099.1 - 4.1e-05 23.0 8.4 0.0036 16.9 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP17099.1 - 9.9e-05 22.8 0.0 0.032 14.8 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEP17099.1 - 0.0066 16.7 2.4 0.68 10.3 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat Virulence_fact PF13769.1 CEP17099.1 - 0.057 13.2 0.6 4.1 7.3 0.2 3.0 3 0 0 3 3 3 0 Virulence factor TPR_14 PF13428.1 CEP17099.1 - 0.058 14.0 0.1 18 6.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HDV_ag PF01517.13 CEP17099.1 - 0.075 12.6 0.5 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen TPR_7 PF13176.1 CEP17099.1 - 0.11 12.3 2.8 1.6 8.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP17099.1 - 0.17 12.4 2.1 4.1 8.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ENTH PF01417.15 CEP17100.1 - 1.4e-48 163.8 0.1 2.5e-48 163.0 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CEP17100.1 - 3.4e-06 25.9 0.1 3.4e-06 25.9 0.1 2.5 2 1 0 2 2 2 1 ANTH domain UIM PF02809.15 CEP17100.1 - 0.04 13.4 0.8 0.04 13.4 0.6 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif CBM_21 PF03370.8 CEP17101.1 - 4e-23 81.5 0.3 1.1e-22 80.1 0.2 1.8 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit PBP1_TM PF14812.1 CEP17101.1 - 0.14 12.4 5.6 0.27 11.5 3.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 CEP17101.1 - 1.3 8.5 9.1 3.2 7.2 6.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 CEP17101.1 - 3.5 7.1 8.4 6 6.4 5.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1162 PF06650.7 CEP17102.1 - 3.8e-66 223.1 1.5 1.1e-62 211.8 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CEP17102.1 - 8.1e-41 138.2 2.0 3e-40 136.4 1.4 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 CEP17102.1 - 6.1e-06 26.3 0.0 2.4e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain bPH_3 PF14470.1 CEP17102.1 - 0.0017 18.5 1.6 1.1 9.5 0.1 3.2 2 0 0 2 2 2 2 Bacterial PH domain Stb3 PF10330.4 CEP17102.1 - 0.07 12.8 0.3 0.2 11.3 0.2 1.7 1 0 0 1 1 1 0 Putative Sin3 binding protein DUF3518 PF12031.3 CEP17103.1 - 8.9e-06 24.6 0.1 8.9e-06 24.6 0.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3518) DUF4446 PF14584.1 CEP17103.1 - 5.6 6.7 9.4 0.38 10.5 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Vps51 PF08700.6 CEP17104.1 - 1e-14 54.1 0.4 1e-14 54.1 0.3 3.0 3 0 0 3 3 3 1 Vps51/Vps67 DUF1837 PF08878.6 CEP17104.1 - 0.99 8.9 10.0 0.076 12.6 0.8 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF1837) Polysacc_deac_1 PF01522.16 CEP17105.1 - 8.4e-24 83.5 0.1 2.2e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase Cloacin_immun PF03513.9 CEP17105.1 - 0.08 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Cloacin immunity protein HMG_box PF00505.14 CEP17106.1 - 2.3e-18 66.1 2.9 4.5e-18 65.2 2.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP17106.1 - 2.1e-09 37.6 1.6 3.8e-09 36.8 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.9 CEP17106.1 - 0.022 14.4 0.2 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Polysacc_deac_1 PF01522.16 CEP17107.1 - 5.6e-26 90.6 0.0 1.1e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Ppx-GppA PF02541.11 CEP17108.1 - 3.3e-44 151.1 0.0 7.2e-44 150.0 0.0 1.5 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Beta_elim_lyase PF01212.16 CEP17109.1 - 4.6e-72 242.6 0.1 5.4e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CEP17109.1 - 0.00016 20.8 0.0 0.0023 17.0 0.0 2.4 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ala_racemase_N PF01168.15 CEP17109.1 - 0.0025 17.3 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Aminotran_1_2 PF00155.16 CEP17109.1 - 0.0047 15.9 0.0 0.012 14.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CEP17109.1 - 0.0075 14.6 0.0 0.013 13.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ACOX PF01756.14 CEP17111.1 - 1.5e-32 112.5 0.0 2.7e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEP17111.1 - 1.1e-13 51.5 0.0 2.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEP17111.1 - 1.4e-10 40.5 0.8 2.8e-10 39.5 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEP17111.1 - 0.0083 16.2 0.3 0.033 14.2 0.2 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lipase_GDSL PF00657.17 CEP17112.1 - 1.1e-11 45.0 0.0 1.3e-10 41.4 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP17112.1 - 9.5e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ParBc PF02195.13 CEP17113.1 - 1e-11 44.7 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 ParB-like nuclease domain Reticulon PF02453.12 CEP17114.1 - 8.3e-19 67.8 1.8 1.4e-18 67.0 1.2 1.3 1 0 0 1 1 1 1 Reticulon DUF2244 PF10003.4 CEP17114.1 - 0.01 15.2 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Class_IIIsignal PF04021.7 CEP17114.1 - 8.9 6.1 9.1 16 5.3 0.6 2.6 2 0 0 2 2 2 0 Class III signal peptide Neur_chan_memb PF02932.11 CEP17115.1 - 3.2 7.5 19.9 1.1e+02 2.5 13.8 2.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mito_carr PF00153.22 CEP17116.1 - 2.1e-50 168.4 2.3 1e-20 73.1 0.1 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein G10 PF01125.12 CEP17117.1 - 1.4e-33 115.4 0.2 2.1e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 G10 protein DUF4112 PF13430.1 CEP17119.1 - 4.1e-25 87.7 0.3 5.6e-25 87.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HSA PF07529.8 CEP17120.1 - 8e-17 60.7 5.5 8e-17 60.7 3.8 5.9 6 2 1 7 7 7 1 HSA Myb_DNA-bind_6 PF13921.1 CEP17120.1 - 2.4e-06 27.5 0.8 2.4e-06 27.5 0.6 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP17120.1 - 0.0022 18.0 0.1 0.0073 16.3 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain RuBisCO_large_N PF02788.11 CEP17120.1 - 2.8 7.6 8.5 10 5.8 1.0 2.7 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain PAS PF00989.19 CEP17121.1 - 3.2e-05 23.6 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold DUF4597 PF15366.1 CEP17121.1 - 0.33 10.5 1.8 0.66 9.5 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Rrn6 PF10214.4 CEP17122.1 - 6.4e-07 27.8 5.5 0.00043 18.5 2.9 2.2 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor HTH_29 PF13551.1 CEP17123.1 - 0.0016 18.5 0.0 0.0069 16.5 0.0 1.9 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 CEP17123.1 - 0.0024 17.4 0.0 0.038 13.6 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP17123.1 - 0.031 14.2 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 CEP17123.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Transposase UBA PF00627.26 CEP17124.1 - 1e-27 95.1 1.9 3.8e-15 55.1 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 CEP17124.1 - 1.6e-19 69.1 2.2 7.2e-19 67.0 1.5 2.2 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 CEP17124.1 - 0.00018 20.8 0.0 0.00036 19.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.5 CEP17124.1 - 0.00025 20.5 0.0 0.39 10.3 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain FeoA PF04023.9 CEP17124.1 - 0.0025 17.7 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 FeoA domain MCM_N PF14551.1 CEP17124.1 - 0.013 15.9 0.3 0.041 14.3 0.1 1.8 1 1 1 2 2 2 0 MCM N-terminal domain Rap1_C PF11626.3 CEP17124.1 - 0.025 14.4 0.0 9.1 6.2 0.0 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CUE PF02845.11 CEP17124.1 - 0.038 13.4 0.1 5.1 6.6 0.0 3.3 2 1 0 2 2 2 0 CUE domain LCAT PF02450.10 CEP17124.1 - 0.075 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1631 PF07793.6 CEP17124.1 - 0.082 11.0 11.6 0.14 10.2 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GSK-3_bind PF05350.7 CEP17124.1 - 1.1 8.7 6.7 7.7 5.8 1.1 2.3 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding NAP PF00956.13 CEP17125.1 - 2.4e-84 282.3 9.6 2.4e-84 282.3 6.6 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) NUDIX PF00293.23 CEP17127.1 - 4.1e-06 26.4 0.0 4.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.24 CEP17128.1 - 2e-43 147.7 0.0 3.5e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP17128.1 - 3.7e-26 90.7 0.0 5.5e-25 87.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.7 CEP17128.1 - 9.6e-16 57.5 0.0 3e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 GUCT (NUC152) domain ResIII PF04851.10 CEP17128.1 - 4e-06 26.7 0.3 1.4e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CEP17128.1 - 7.3e-05 21.9 7.7 0.0027 16.8 0.0 2.3 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit AAA_11 PF13086.1 CEP17128.1 - 0.084 12.4 0.8 5.3 6.5 0.7 2.7 2 1 0 2 2 2 0 AAA domain DnaJ PF00226.26 CEP17129.1 - 2.3e-16 59.2 0.2 3.3e-16 58.7 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L31e PF01198.14 CEP17130.1 - 6.2e-34 115.5 3.3 7.9e-34 115.1 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e zf-C2H2 PF00096.21 CEP17131.1 - 6.2e-19 67.1 39.6 5.3e-05 23.3 3.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP17131.1 - 5.2e-15 54.5 33.0 0.00058 20.0 0.8 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP17131.1 - 5.5e-10 39.0 12.6 3.5e-06 27.0 1.9 6.1 6 0 0 6 6 6 3 Zinc-finger double domain Zip PF02535.17 CEP17131.1 - 0.0055 15.7 3.6 0.25 10.2 0.0 2.3 2 0 0 2 2 2 1 ZIP Zinc transporter CDK2AP PF09806.4 CEP17131.1 - 0.86 9.8 11.0 4.3 7.5 0.9 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ogr_Delta PF04606.7 CEP17131.1 - 0.93 9.2 8.4 4.5 7.0 0.0 4.2 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger Ligase_CoA PF00549.14 CEP17132.1 - 1.7e-15 56.9 0.1 3.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Citrate_synt PF00285.16 CEP17132.1 - 3.9e-15 55.4 0.0 1.3e-13 50.4 0.0 2.6 1 1 1 2 2 2 1 Citrate synthase CoA_binding PF02629.14 CEP17132.1 - 3.4e-13 49.9 0.0 7.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 CEP17132.1 - 1.3e-07 31.1 0.0 2.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CEP17132.1 - 3.3e-06 26.7 0.5 4.8e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain NdhM PF10664.4 CEP17134.1 - 0.021 14.6 2.2 0.039 13.8 1.1 1.7 1 1 1 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M Laminin_II PF06009.7 CEP17134.1 - 0.077 12.7 9.8 0.17 11.6 6.8 1.6 1 0 0 1 1 1 0 Laminin Domain II HSP70 PF00012.15 CEP17134.1 - 1.1 7.1 8.0 1.7 6.4 5.6 1.3 1 0 0 1 1 1 0 Hsp70 protein Syntaxin PF00804.20 CEP17134.1 - 1.3 9.2 22.5 0.94 9.6 0.1 3.9 2 1 2 4 4 4 0 Syntaxin DUF4404 PF14357.1 CEP17134.1 - 7.5 7.0 9.6 5 7.6 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Muskelin_N PF06588.6 CEP17136.1 - 3.8e-74 248.6 0.4 6.1e-74 248.0 0.3 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 CEP17136.1 - 8.6e-28 95.8 3.9 1.7e-06 27.9 0.0 7.3 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CEP17136.1 - 5.3e-21 74.1 3.6 7.5e-05 22.4 0.2 5.8 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP17136.1 - 3.4e-15 55.4 2.8 1.2e-05 25.2 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CEP17136.1 - 1.8e-13 50.1 8.2 0.0014 18.5 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CEP17136.1 - 8.7e-12 44.4 9.2 3.5e-07 29.6 0.1 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CEP17136.1 - 6.1e-09 35.3 5.6 0.00071 19.2 0.2 4.5 5 0 0 5 5 5 2 Kelch motif F5_F8_type_C PF00754.20 CEP17136.1 - 0.00024 20.9 0.1 0.00091 19.0 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain Zn_clus PF00172.13 CEP17137.1 - 2e-11 43.5 11.4 3.3e-11 42.8 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.7 CEP17137.1 - 0.13 10.5 4.9 0.19 10.0 3.4 1.2 1 0 0 1 1 1 0 Per os infectivity Gal4_dimer PF03902.8 CEP17137.1 - 0.21 11.5 1.2 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Gal4-like dimerisation domain Rep_fac-A_C PF08646.5 CEP17137.1 - 0.35 10.5 5.8 0.7 9.5 4.1 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain AA_permease_2 PF13520.1 CEP17139.1 - 3e-61 207.2 58.0 3.5e-61 207.0 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP17139.1 - 1.2e-32 112.9 45.6 1.9e-32 112.2 31.6 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.6 CEP17139.1 - 0.21 10.5 5.1 0.14 11.1 1.9 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 RRM_1 PF00076.17 CEP17140.1 - 4.6e-29 99.8 4.7 5.8e-17 61.0 0.0 3.4 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17140.1 - 1.6e-25 88.8 3.2 8.7e-14 51.2 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP17140.1 - 1.9e-09 37.2 0.1 1.3e-05 24.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_Tnp_IS630 PF01710.11 CEP17141.1 - 0.0018 17.9 0.7 0.0018 17.9 0.5 2.0 2 0 0 2 2 2 1 Transposase Cobl PF09469.5 CEP17141.1 - 5.5 7.0 9.2 1.3 9.0 3.2 2.1 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain Clathrin PF00637.15 CEP17142.1 - 2.6e-214 701.4 50.0 5.5e-37 126.5 1.0 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CEP17142.1 - 1.8e-25 88.5 0.1 9.7e-25 86.2 0.1 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 CEP17142.1 - 6.7e-24 82.4 1.5 0.00021 21.3 0.0 6.8 7 0 0 7 7 6 4 Clathrin propeller repeat Coatomer_WDAD PF04053.9 CEP17142.1 - 2.8e-10 39.5 2.7 2.3e-05 23.4 0.1 3.8 3 0 0 3 3 3 2 Coatomer WD associated region Clathrin-link PF09268.5 CEP17142.1 - 4e-09 35.3 0.4 1e-08 33.9 0.3 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_11 PF13414.1 CEP17142.1 - 1.5e-05 24.5 6.8 14 5.4 0.2 7.1 6 1 1 7 7 6 0 TPR repeat TPR_12 PF13424.1 CEP17142.1 - 0.00037 20.3 13.2 1.8 8.5 0.0 6.7 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP17142.1 - 0.00051 20.4 10.7 47 5.0 0.0 9.2 11 1 1 12 12 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP17142.1 - 0.0012 18.4 11.3 2.8 7.9 0.0 7.4 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP17142.1 - 0.0026 17.5 8.8 4.8 7.3 0.0 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEP17142.1 - 0.0031 17.0 10.2 1.7 8.4 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEP17142.1 - 0.0089 16.3 11.6 5.8 7.3 0.1 7.1 9 0 0 9 9 8 1 Tetratricopeptide repeat PPR PF01535.15 CEP17142.1 - 0.056 13.4 1.0 26 5.0 0.0 5.2 5 0 0 5 5 5 0 PPR repeat Acyl-CoA_dh_1 PF00441.19 CEP17143.1 - 2.8e-47 160.5 3.8 2.8e-47 160.5 2.6 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEP17143.1 - 2.7e-23 82.6 0.0 1.2e-22 80.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEP17143.1 - 3.9e-22 78.9 1.2 7.1e-22 78.1 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEP17143.1 - 1.9e-19 68.8 0.1 6.7e-19 67.1 0.0 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Phage_integrase PF00589.17 CEP17144.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 2 0 0 2 2 2 0 Phage integrase family DASH_Ask1 PF08655.5 CEP17144.1 - 0.11 12.3 0.1 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Ask1 GATA PF00320.22 CEP17145.1 - 1.6e-21 75.3 19.2 3.1e-16 58.4 4.0 2.3 2 0 0 2 2 2 2 GATA zinc finger Cytochrom_c3_2 PF14537.1 CEP17145.1 - 0.0004 20.6 9.7 0.093 13.0 1.5 2.4 2 0 0 2 2 2 2 Cytochrome c3 Cytochrome_C7 PF14522.1 CEP17145.1 - 0.0022 17.5 11.7 0.073 12.7 2.2 2.4 2 0 0 2 2 2 2 Cytochrome c7 TF_Zn_Ribbon PF08271.7 CEP17145.1 - 0.0038 16.5 3.9 0.91 8.8 0.4 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Elf1 PF05129.8 CEP17145.1 - 0.026 14.2 3.2 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF3677 PF12432.3 CEP17145.1 - 0.14 12.5 5.4 0.41 11.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3677) Auxin_repressed PF05564.7 CEP17145.1 - 0.88 10.1 15.6 0.095 13.3 1.4 3.3 3 0 0 3 3 3 0 Dormancy/auxin associated protein NMD3 PF04981.8 CEP17145.1 - 1.8 7.6 7.7 1.6 7.7 2.2 2.1 1 1 1 2 2 2 0 NMD3 family PSCyt3 PF07627.6 CEP17145.1 - 5 7.0 8.9 3.4 7.5 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) DZR PF12773.2 CEP17145.1 - 6.4 6.6 11.4 10 6.0 0.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 CEP17145.1 - 9.3 5.9 8.3 9.9 5.8 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 F-box-like PF12937.2 CEP17146.1 - 4.8e-08 32.5 0.1 1.2e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP17146.1 - 4.6e-05 22.9 0.7 0.00016 21.2 0.1 2.2 2 0 0 2 2 2 1 F-box domain RRF_GI PF12614.3 CEP17146.1 - 0.015 15.0 0.8 0.023 14.5 0.1 1.7 2 0 0 2 2 2 0 Ribosome recycling factor PRANC PF09372.5 CEP17146.1 - 0.19 11.7 2.8 4.6 7.2 0.0 3.0 3 1 0 3 3 3 0 PRANC domain zf-MYND PF01753.13 CEP17147.1 - 5e-09 35.8 15.6 9.1e-09 35.0 10.8 1.4 1 0 0 1 1 1 1 MYND finger Sel1 PF08238.7 CEP17147.1 - 4.2e-07 30.3 13.5 0.12 13.0 0.3 6.0 5 1 0 5 5 5 3 Sel1 repeat Carot_N PF09150.5 CEP17147.1 - 0.084 12.5 0.1 0.31 10.7 0.1 1.9 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal TPR_8 PF13181.1 CEP17147.1 - 2.9 7.8 8.9 19 5.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-Tim10_DDP PF02953.10 CEP17149.1 - 2.5e-24 84.3 2.9 3.4e-24 83.8 2.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vps54 PF07928.7 CEP17149.1 - 0.0092 16.1 0.0 0.01 15.9 0.0 1.2 1 1 0 1 1 1 1 Vps54-like protein DUF842 PF05811.8 CEP17149.1 - 0.1 12.0 2.9 0.13 11.7 2.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Methyltransf_11 PF08241.7 CEP17150.1 - 5.9e-06 26.6 0.0 1.6e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP17150.1 - 1.9e-05 24.4 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP17150.1 - 0.0075 16.7 0.2 0.029 14.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF3179 PF11376.3 CEP17150.1 - 0.042 13.0 0.7 0.1 11.7 0.2 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3179) HTH_32 PF13565.1 CEP17151.1 - 0.0056 17.4 0.0 0.01 16.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain PRELI PF04707.9 CEP17152.1 - 4.1e-48 162.8 0.5 4.9e-48 162.6 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family zf-MIZ PF02891.15 CEP17153.1 - 3.9e-12 45.4 3.6 8.6e-12 44.3 2.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_3 PF13920.1 CEP17153.1 - 0.18 11.5 2.0 0.37 10.4 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP17153.1 - 2 8.5 5.8 0.58 10.2 1.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) M20_dimer PF07687.9 CEP17154.1 - 2.5e-10 40.0 0.0 5.4e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain PPR_2 PF13041.1 CEP17155.1 - 1.4e-10 40.9 4.4 0.44 10.5 0.0 6.0 6 0 0 6 6 6 4 PPR repeat family PPR_3 PF13812.1 CEP17155.1 - 3.5e-09 36.2 10.2 0.00083 19.4 0.1 7.4 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 CEP17155.1 - 7.9e-07 28.6 8.4 0.0024 17.7 0.0 6.4 7 0 0 7 7 7 1 PPR repeat DUF1955 PF09205.5 CEP17155.1 - 0.11 12.0 1.0 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) Sec7 PF01369.15 CEP17156.1 - 8.6e-64 214.7 0.0 4.5e-63 212.3 0.0 2.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CEP17156.1 - 1.8e-47 160.9 2.6 6.2e-47 159.1 1.0 2.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CEP17156.1 - 2.3e-30 103.9 10.4 8.1e-30 102.1 0.1 5.5 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Zn_clus PF00172.13 CEP17157.1 - 0.00038 20.3 11.1 0.00088 19.1 7.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 CEP17159.1 - 1.4e-16 60.5 0.1 4.2e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEP17159.1 - 8.2e-09 35.8 0.3 2.4e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.12 CEP17159.1 - 0.0007 19.6 2.0 0.0019 18.2 1.4 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 CEP17159.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 CEP17159.1 - 0.0092 15.5 0.1 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Activator_LAG-3 PF11498.3 CEP17161.1 - 0.0039 16.0 18.1 0.0043 15.8 12.5 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 S-AdoMet_synt_M PF02772.11 CEP17161.1 - 0.067 13.1 5.4 0.033 14.1 2.3 1.5 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain Borrelia_P83 PF05262.6 CEP17161.1 - 0.16 10.1 12.4 0.19 9.9 8.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pepsin-I3 PF06394.8 CEP17161.1 - 0.28 10.8 12.4 0.61 9.7 8.6 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Fmp27_WPPW PF10359.4 CEP17161.1 - 0.48 8.7 12.5 0.58 8.5 8.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4557 PF15101.1 CEP17161.1 - 1.3 8.8 10.2 1.6 8.5 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) OmpH PF03938.9 CEP17161.1 - 2.3 8.1 19.0 3 7.7 13.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDE_3 PF13358.1 CEP17162.1 - 1.8e-15 56.9 0.0 2.9e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP17162.1 - 2.4e-09 37.1 0.1 1.6e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 CEP17162.1 - 1.4e-06 28.3 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP17162.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 CEP17162.1 - 0.1 12.2 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Ada3 PF10198.4 CEP17163.1 - 1.4e-34 118.6 3.3 1.4e-34 118.6 2.3 2.5 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 P21-Arc PF04062.9 CEP17165.1 - 1.2e-50 171.6 0.1 1.4e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit MNSV_P7B PF06692.6 CEP17165.1 - 0.01 15.5 0.1 0.11 12.2 0.0 2.3 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein SET PF00856.23 CEP17166.1 - 1.4e-07 31.9 0.0 6.5e-07 29.7 0.0 1.8 1 1 1 2 2 2 1 SET domain Rgp1 PF08737.5 CEP17168.1 - 1.3e-81 274.8 3.1 1.9e-79 267.6 2.2 2.5 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 CEP17168.1 - 0.0011 19.0 0.8 0.27 11.3 0.0 3.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Tom5 PF10642.4 CEP17168.1 - 0.004 16.7 1.3 0.008 15.8 0.9 1.6 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase TOM_sub5 PF15178.1 CEP17168.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog PH PF00169.24 CEP17169.1 - 0.007 16.5 2.4 0.007 16.5 1.7 3.2 3 0 0 3 3 3 1 PH domain DUF2346 PF09803.4 CEP17170.1 - 1.3e-09 37.7 0.5 2e-09 37.1 0.3 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF4316 PF14195.1 CEP17170.1 - 0.086 12.9 0.3 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) PHD PF00628.24 CEP17171.1 - 1.4e-09 37.4 8.8 1.4e-09 37.4 6.1 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CEP17171.1 - 0.072 12.4 3.8 0.15 11.4 2.7 1.5 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.27 CEP17172.1 - 2.4e-44 147.6 1.7 3.2e-08 33.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CEP17172.1 - 1.2e-21 76.3 0.5 3.4e-21 74.9 0.4 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CEP17172.1 - 2.3e-06 27.4 0.4 0.03 14.0 0.0 3.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ecl1 PF12855.2 CEP17172.1 - 0.001 18.3 0.1 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 CEP17172.1 - 0.057 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 MYND finger FMO-like PF00743.14 CEP17173.1 - 4.3e-39 134.1 0.0 7.8e-22 77.1 0.0 3.9 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CEP17173.1 - 8.4e-21 74.9 0.0 1.2e-19 71.2 0.0 2.3 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEP17173.1 - 1.4e-08 34.0 0.0 1.1e-07 31.1 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CEP17173.1 - 4.7e-08 33.1 0.0 0.015 15.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEP17173.1 - 1.1e-06 28.5 0.1 0.00013 21.7 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CEP17173.1 - 1.3e-06 28.2 0.0 3.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEP17173.1 - 3.9e-05 22.7 0.1 0.00038 19.4 0.1 2.4 2 2 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CEP17173.1 - 0.00013 21.1 0.0 0.00072 18.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 CEP17173.1 - 0.00027 21.1 0.0 0.16 12.2 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding Thi4 PF01946.12 CEP17173.1 - 0.00041 19.5 0.1 0.0015 17.7 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_2 PF03446.10 CEP17173.1 - 0.00095 19.0 0.0 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 CEP17173.1 - 0.00096 17.7 0.1 0.0014 17.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 CEP17173.1 - 0.0018 17.6 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 CEP17173.1 - 0.0079 16.5 3.2 1.8 8.9 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CEP17173.1 - 0.0094 15.5 0.2 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CEP17173.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CEP17173.1 - 0.016 14.0 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 CEP17173.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 CEP17173.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 CEP17173.1 - 0.02 14.2 0.0 0.05 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 CEP17173.1 - 0.027 13.6 0.0 0.074 12.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CEP17173.1 - 0.029 14.4 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 CEP17173.1 - 0.087 11.6 0.0 0.18 10.5 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.1 CEP17173.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_10 PF13460.1 CEP17173.1 - 0.73 9.8 3.4 0.96 9.4 0.3 2.6 3 0 0 3 3 3 0 NADH(P)-binding DAO PF01266.19 CEP17174.1 - 0.11 11.3 0.2 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Phosphorylase PF00343.15 CEP17175.1 - 0 1038.0 0.1 0 1037.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase ESCRT-II PF05871.7 CEP17176.1 - 5.1e-29 100.9 3.9 3e-22 79.0 0.9 2.2 1 1 1 2 2 2 2 ESCRT-II complex subunit Peptidase_M24 PF00557.19 CEP17177.1 - 1.1e-42 145.9 0.0 1.7e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CEP17177.1 - 4.9e-24 85.2 0.0 1.1e-21 77.7 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain SPOC PF07744.8 CEP17177.1 - 0.014 15.8 0.0 4.2 7.8 0.0 2.3 2 0 0 2 2 2 0 SPOC domain PAH PF02671.16 CEP17178.1 - 1.7e-43 145.9 4.5 9.7e-20 69.9 0.7 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CEP17178.1 - 3.6e-36 122.9 0.2 9.5e-36 121.6 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor DDE_3 PF13358.1 CEP17179.1 - 2.1e-28 98.8 0.0 2.7e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP17179.1 - 0.00041 20.4 0.0 0.0006 19.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 CEP17179.1 - 0.001 18.2 0.0 0.022 13.9 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP17181.1 - 9.2e-07 29.0 0.1 1.4e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP17181.1 - 6.4e-06 26.0 1.3 1e-05 25.3 0.9 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP17181.1 - 0.00012 21.6 0.2 0.00021 20.8 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 CEP17181.1 - 0.0016 19.1 0.1 0.0029 18.3 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CEP17181.1 - 0.036 13.2 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.22 CEP17181.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.1 CEP17182.1 - 6.7e-06 25.5 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP17182.1 - 1.4e-05 24.9 0.2 2.7e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 CEP17182.1 - 6.5e-05 23.0 0.0 7.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 CEP17182.1 - 0.012 14.7 0.1 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1 PF01527.15 CEP17182.1 - 0.018 15.0 0.1 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Transposase HTH_17 PF12728.2 CEP17182.1 - 0.035 14.3 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.1 CEP17182.1 - 0.055 13.0 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain BrkDBD PF09607.5 CEP17182.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Brinker DNA-binding domain Mcp5_PH PF12814.2 CEP17183.1 - 5.6e-34 116.7 0.0 1.7e-33 115.1 0.0 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 CEP17183.1 - 0.017 15.2 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 PH domain SAP PF02037.22 CEP17184.1 - 1.1e-10 40.7 2.2 1.1e-10 40.7 1.6 2.5 2 0 0 2 2 2 1 SAP domain Pkinase PF00069.20 CEP17185.1 - 2.1e-69 233.5 0.0 1.2e-68 231.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17185.1 - 7.1e-52 176.0 0.0 1.5e-51 174.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.26 CEP17185.1 - 3.8e-10 39.7 0.1 1.2e-09 38.1 0.1 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain Kinase-like PF14531.1 CEP17185.1 - 4.8e-07 29.0 0.0 5.1e-05 22.3 0.0 2.5 1 1 1 2 2 2 1 Kinase-like C1_1 PF00130.17 CEP17185.1 - 3e-05 23.6 10.5 6e-05 22.6 7.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.17 CEP17185.1 - 0.0041 16.4 0.0 0.0096 15.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family CDC24 PF06395.6 CEP17185.1 - 0.011 15.7 0.3 0.032 14.2 0.0 1.9 2 0 0 2 2 2 0 CDC24 Calponin CAMSAP_CH PF11971.3 CEP17185.1 - 0.019 14.6 1.3 0.076 12.6 0.0 2.7 3 0 0 3 3 3 0 CAMSAP CH domain N_NLPC_P60 PF12912.2 CEP17185.1 - 7.4 6.6 8.8 1.4 9.0 0.6 3.0 3 0 0 3 3 3 0 NLPC_P60 stabilising domain, N term Acetyltransf_1 PF00583.19 CEP17186.1 - 1.1e-15 57.3 0.0 1.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP17186.1 - 3.9e-12 46.1 0.1 5.6e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEP17186.1 - 2e-08 34.3 0.0 2.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEP17186.1 - 5e-07 29.5 0.0 9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 CEP17186.1 - 8.9e-06 25.8 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEP17186.1 - 2.6e-05 24.1 0.0 3.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP17186.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Homeobox PF00046.24 CEP17187.1 - 5.8e-18 64.2 2.9 5.8e-18 64.2 2.0 2.6 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.6 CEP17187.1 - 0.01 15.5 0.1 0.025 14.2 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain DEAD PF00270.24 CEP17188.1 - 3.4e-36 124.2 0.4 7.3e-36 123.1 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP17188.1 - 1.1e-23 82.8 0.0 2.5e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP17188.1 - 3.2e-06 27.0 0.1 3.2e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CEP17188.1 - 0.0092 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.1 CEP17188.1 - 0.018 14.1 0.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 CEP17188.1 - 0.023 14.4 0.0 0.096 12.4 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain Helicase_RecD PF05127.9 CEP17188.1 - 0.053 13.1 1.7 0.075 12.6 0.0 2.0 2 0 0 2 2 2 0 Helicase zf-C2H2_jaz PF12171.3 CEP17189.1 - 1.2e-06 28.4 4.4 1.9e-06 27.8 3.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CEP17189.1 - 0.048 13.7 2.5 0.057 13.5 1.6 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SYF2 PF08231.7 CEP17189.1 - 0.049 13.7 1.0 0.063 13.3 0.7 1.2 1 0 0 1 1 1 0 SYF2 splicing factor Sec66 PF09802.4 CEP17190.1 - 0.0025 17.2 0.7 0.0025 17.2 0.5 2.1 2 0 0 2 2 2 1 Preprotein translocase subunit Sec66 HSBP1 PF06825.7 CEP17190.1 - 0.0035 16.8 0.0 0.67 9.5 0.0 3.7 4 1 0 4 4 4 1 Heat shock factor binding protein 1 RsbU_N PF08673.5 CEP17190.1 - 0.078 12.9 0.4 0.29 11.1 0.3 2.0 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Cupin_4 PF08007.7 CEP17190.1 - 0.87 8.7 12.2 0.14 11.3 0.6 3.7 4 1 0 4 4 4 0 Cupin superfamily protein rve PF00665.21 CEP17192.1 - 5.6e-10 39.3 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP17192.1 - 5.4e-06 25.9 0.3 1.5e-05 24.5 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1524 PF07510.6 CEP17192.1 - 0.36 10.6 2.7 4 7.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) Retrotrans_gag PF03732.12 CEP17193.1 - 0.00029 20.8 0.2 0.0016 18.4 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein amfpi-1 PF12190.3 CEP17193.1 - 0.13 12.7 2.0 0.3 11.6 1.4 1.6 1 0 0 1 1 1 0 Fungal protease inhibitor Ebp2 PF05890.7 CEP17197.1 - 9.7e-35 120.1 25.3 3.5e-33 115.0 17.5 2.1 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF3881 PF12997.2 CEP17197.1 - 0.091 11.7 1.3 0.15 11.0 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) TGS PF02824.16 CEP17198.1 - 5.6e-21 74.1 0.1 1e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CEP17198.1 - 5.5e-18 65.0 0.0 1.1e-17 64.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP17198.1 - 2.8e-12 46.1 0.0 5.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CEP17198.1 - 0.00019 21.9 0.0 0.00095 19.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CEP17198.1 - 0.00037 20.3 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 CEP17198.1 - 0.006 16.0 2.2 7.4 5.9 0.0 3.5 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CEP17198.1 - 0.007 15.5 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 CEP17198.1 - 0.0082 14.9 0.1 0.017 13.9 0.1 1.5 1 0 0 1 1 1 1 ArgK protein AAA_28 PF13521.1 CEP17198.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 CEP17198.1 - 0.013 14.7 0.0 0.038 13.2 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family AIG1 PF04548.11 CEP17198.1 - 0.046 12.8 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Claudin_2 PF13903.1 CEP17199.1 - 0.02 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.18 CEP17200.1 - 8.1 6.2 7.9 2.3 8.0 0.4 2.1 1 1 1 2 2 2 0 Membrane-associating domain DUF4590 PF15257.1 CEP17201.1 - 0.009 15.8 1.4 0.015 15.0 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) TMEM238 PF15125.1 CEP17201.1 - 7.7 6.5 7.1 0.41 10.5 1.5 1.4 2 0 0 2 2 2 0 TMEM238 protein family GCV_T PF01571.16 CEP17202.1 - 0.03 13.6 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain DUF2746 PF10874.3 CEP17202.1 - 0.041 14.0 0.4 5.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) adh_short PF00106.20 CEP17203.1 - 2.3e-29 102.4 0.4 3.1e-29 102.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP17203.1 - 1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP17203.1 - 6.7e-13 48.6 0.1 9.4e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CEP17203.1 - 0.00022 20.2 0.1 0.00033 19.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CEP17203.1 - 0.013 15.3 0.5 0.034 13.9 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CEP17203.1 - 0.046 13.7 0.4 0.069 13.1 0.3 1.5 1 1 0 1 1 1 0 NADH(P)-binding Methyltransf_18 PF12847.2 CEP17203.1 - 0.08 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.14 CEP17203.1 - 0.11 11.1 0.0 0.99 8.0 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family ArfGap PF01412.13 CEP17204.1 - 1.4e-35 121.5 2.1 2e-35 121.0 0.0 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 CEP17204.1 - 4.9e-12 45.9 2.5 6.6e-12 45.5 0.4 2.2 2 0 0 2 2 2 1 PH domain UBX PF00789.15 CEP17205.1 - 1.7e-10 40.7 0.0 4.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain Ribosomal_60s PF00428.14 CEP17206.1 - 3e-27 94.8 11.2 3.5e-27 94.6 7.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MAGE_N PF12440.3 CEP17206.1 - 2.5 8.4 8.7 2.7 8.3 5.5 1.4 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal zf-C2H2 PF00096.21 CEP17207.1 - 5.4e-05 23.2 8.5 0.45 10.9 0.6 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP17207.1 - 0.0013 18.9 18.9 0.11 12.8 0.7 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger CTDII PF01556.13 CEP17209.1 - 1e-18 67.0 1.1 8.9e-13 47.9 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CEP17209.1 - 3.2e-14 52.3 0.7 6.6e-14 51.4 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CEP17209.1 - 2.9e-06 27.2 7.7 2.9e-06 27.2 5.3 2.1 2 0 0 2 2 2 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 CEP17209.1 - 4.1 7.7 8.1 20 5.6 5.4 2.3 1 1 1 2 2 2 0 Cytochrome c3 Ribosomal_S25 PF03297.10 CEP17210.1 - 2.1e-42 143.4 2.5 2.4e-42 143.2 1.7 1.1 1 0 0 1 1 1 1 S25 ribosomal protein BioT2 PF15368.1 CEP17210.1 - 0.0098 15.6 0.5 0.012 15.3 0.3 1.2 1 0 0 1 1 1 1 Spermatogenesis family BioT2 HTH_24 PF13412.1 CEP17210.1 - 0.011 15.1 0.4 0.016 14.6 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 CEP17210.1 - 0.034 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 MarR family RNA_pol_Rpc34 PF05158.7 CEP17210.1 - 0.052 12.7 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit MoaC PF01967.16 CEP17211.1 - 3.1e-52 175.8 2.4 3.6e-52 175.6 1.6 1.0 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 CEP17212.1 - 9e-21 73.8 0.1 1e-20 73.6 0.1 1.0 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C SPASM PF13186.1 CEP17212.1 - 0.035 14.4 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain Radical_SAM PF04055.16 CEP17213.1 - 1.5e-27 96.7 0.0 2e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 CEP17213.1 - 2.4e-06 27.7 0.0 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 CEP17213.1 - 5.1e-05 23.2 0.0 9.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Mob_synth_C PF06463.8 CEP17213.1 - 0.00016 21.3 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C ThiG PF05690.9 CEP17213.1 - 0.003 16.6 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG AA_permease_2 PF13520.1 CEP17214.1 - 4.5e-55 186.8 55.8 5.7e-55 186.5 38.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP17214.1 - 3.5e-18 65.2 46.8 3.5e-18 65.2 32.4 1.3 1 1 0 1 1 1 1 Amino acid permease DUF2370 PF10176.4 CEP17215.1 - 9.3e-67 224.7 3.0 1.5e-65 220.8 0.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF4364 PF14277.1 CEP17216.1 - 0.12 12.0 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DEAD PF00270.24 CEP17217.1 - 7.1e-43 146.0 0.1 1.3e-42 145.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP17217.1 - 8.4e-24 83.2 0.1 2.3e-23 81.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CEP17217.1 - 0.025 13.6 0.1 0.07 12.1 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GTP_cyclohydro2 PF00925.15 CEP17218.1 - 7.5e-64 214.0 0.4 2.3e-58 196.1 0.2 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II GN3L_Grn1 PF08701.6 CEP17219.1 - 2.5e-23 81.7 18.5 2.5e-23 81.7 12.8 2.2 1 1 1 2 2 2 1 GNL3L/Grn1 putative GTPase DUF3138 PF11336.3 CEP17219.1 - 1.4 6.9 8.3 1.7 6.7 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_S8e PF01201.17 CEP17219.1 - 2.1 8.4 10.7 3.9 7.6 7.4 1.5 1 1 0 1 1 1 0 Ribosomal protein S8e RR_TM4-6 PF06459.7 CEP17219.1 - 2.2 8.1 12.6 2.5 7.9 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gly-zipper_Omp PF13488.1 CEP17220.1 - 0.01 15.4 0.4 0.018 14.6 0.3 1.3 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 CEP17220.1 - 0.037 13.5 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Adeno_E3_CR2 PF02439.10 CEP17220.1 - 0.099 12.2 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 WD40 PF00400.27 CEP17221.1 - 6.9e-56 184.2 25.5 3e-09 36.3 0.5 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP17221.1 - 7.5e-14 50.7 10.6 0.0012 17.1 0.5 5.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP17221.1 - 6e-13 48.2 0.2 1.4e-12 47.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP17221.1 - 5.1e-09 35.5 0.1 1.4e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 CEP17221.1 - 0.00026 19.8 8.5 0.68 8.6 0.3 4.3 2 2 2 4 4 4 4 Nup133 N terminal like Elongin_A PF06881.6 CEP17221.1 - 0.068 13.5 0.1 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Rio2_N PF09202.6 CEP17222.1 - 0.097 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Rio2, N-terminal bZIP_1 PF00170.16 CEP17223.1 - 4.6e-11 42.4 4.1 1.7e-10 40.7 2.8 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP17223.1 - 0.00071 19.3 14.0 0.055 13.3 2.2 3.0 1 1 1 2 2 2 2 Basic region leucine zipper TMF_DNA_bd PF12329.3 CEP17223.1 - 0.094 12.5 3.2 0.3 10.9 2.2 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BMFP PF04380.8 CEP17223.1 - 0.3 11.2 4.4 0.68 10.1 3.1 1.6 1 0 0 1 1 1 0 Membrane fusogenic activity HAUS6_N PF14661.1 CEP17223.1 - 1.4 8.2 10.9 0.095 12.0 3.4 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Uds1 PF15456.1 CEP17223.1 - 4.5 7.2 12.9 0.041 13.8 1.4 2.7 3 0 0 3 3 3 0 Up-regulated During Septation GalKase_gal_bdg PF10509.4 CEP17224.1 - 9.1e-22 76.0 0.1 1.9e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CEP17224.1 - 1.8e-14 53.5 2.6 5.1e-14 52.0 1.8 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CEP17224.1 - 5.9e-12 45.6 0.0 1.3e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4 PF04545.11 CEP17224.1 - 0.093 12.0 0.0 5.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Aldedh PF00171.17 CEP17225.1 - 6.7e-129 430.2 0.0 7.8e-129 429.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RPEL PF02755.10 CEP17226.1 - 2.2e-17 61.7 9.7 7.8e-09 34.5 0.3 2.8 3 0 0 3 3 3 2 RPEL repeat Sigma70_r3 PF04539.11 CEP17226.1 - 0.007 16.2 1.0 0.029 14.2 0.1 2.0 1 1 1 2 2 2 1 Sigma-70 region 3 DnaI_N PF07319.6 CEP17226.1 - 0.071 13.3 0.1 0.1 12.8 0.1 1.4 1 1 0 1 1 1 0 Primosomal protein DnaI N-terminus TPT PF03151.11 CEP17227.1 - 1.2e-05 25.0 11.5 1.2e-05 25.0 8.0 2.8 2 2 0 2 2 2 1 Triose-phosphate Transporter family DUF2273 PF10031.4 CEP17227.1 - 4.5 6.9 8.1 0.67 9.6 1.6 2.6 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Kelch_5 PF13854.1 CEP17228.1 - 0.0005 19.9 0.1 1.4 9.0 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CEP17228.1 - 0.00065 19.7 1.7 0.42 10.8 0.0 3.9 3 1 1 4 4 4 1 Kelch motif Kelch_3 PF13415.1 CEP17228.1 - 0.012 15.7 4.1 12 6.2 0.0 4.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Amnionless PF14828.1 CEP17228.1 - 0.012 14.1 0.2 0.033 12.7 0.0 1.7 1 1 1 2 2 2 0 Amnionless Kelch_4 PF13418.1 CEP17228.1 - 0.043 13.5 5.2 1.2 8.9 0.0 4.5 5 1 1 6 6 6 0 Galactose oxidase, central domain Kelch_1 PF01344.20 CEP17228.1 - 0.053 13.0 1.8 8.5 6.0 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 CEP17228.1 - 0.12 12.1 0.2 35 4.3 0.0 4.5 6 0 0 6 6 6 0 Kelch motif VSP PF03302.8 CEP17228.1 - 0.15 10.6 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Syndecan PF01034.15 CEP17228.1 - 0.19 11.3 1.5 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Syndecan domain CTP_transf_1 PF01148.15 CEP17233.1 - 2.4e-16 60.1 8.8 2.2e-14 53.7 6.1 2.1 1 1 0 1 1 1 1 Cytidylyltransferase family G3P_acyltransf PF02660.10 CEP17233.1 - 3.7 7.0 9.0 0.49 9.9 3.1 1.8 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase RRM_1 PF00076.17 CEP17234.1 - 1.4e-18 66.3 0.1 1.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17234.1 - 9.6e-13 47.9 0.1 1.5e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP17234.1 - 4.4e-10 39.2 0.0 6.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC6 PF05460.8 CEP17234.1 - 3 6.8 10.7 4.5 6.2 7.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PX PF00787.19 CEP17235.1 - 3e-21 75.3 0.1 7.9e-21 73.9 0.1 1.8 1 0 0 1 1 1 1 PX domain FAM92 PF06730.6 CEP17235.1 - 0.042 13.1 2.5 0.087 12.1 1.8 1.5 1 0 0 1 1 1 0 FAM92 protein Sec2p PF06428.6 CEP17236.1 - 1.2e-11 44.3 9.8 1.2e-11 44.3 6.8 1.8 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Orbi_VP5 PF00901.12 CEP17236.1 - 0.0029 15.8 6.7 0.0043 15.3 4.6 1.3 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP5 PNRC PF15365.1 CEP17236.1 - 0.033 14.1 0.3 0.12 12.3 0.2 1.9 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator IFT57 PF10498.4 CEP17236.1 - 0.078 11.7 14.1 0.11 11.1 9.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 V_ATPase_I PF01496.14 CEP17236.1 - 0.079 10.8 6.3 0.1 10.4 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myosin_tail_1 PF01576.14 CEP17236.1 - 0.079 10.6 13.5 0.11 10.1 9.4 1.1 1 0 0 1 1 1 0 Myosin tail Laminin_II PF06009.7 CEP17236.1 - 0.56 9.9 6.7 2.6 7.8 3.0 2.3 1 1 1 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 CEP17236.1 - 1 9.1 15.1 1.6 8.5 10.5 1.2 1 0 0 1 1 1 0 Tropomyosin like AAA_13 PF13166.1 CEP17236.1 - 1.6 7.0 8.5 2.4 6.5 5.9 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 CEP17236.1 - 5 5.9 12.8 11 4.8 8.9 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CEP17236.1 - 5.3 6.0 13.5 8 5.4 9.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinesin PF00225.18 CEP17237.1 - 8.9e-94 313.9 6.6 8.9e-94 313.9 4.6 2.0 2 0 0 2 2 2 1 Kinesin motor domain DisA_N PF02457.11 CEP17237.1 - 0.08 12.0 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding MFS_1 PF07690.11 CEP17238.1 - 4.8e-33 114.3 66.6 4.7e-19 68.3 21.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily RhoGEF PF00621.15 CEP17238.1 - 4.2e-26 91.9 0.1 8.9e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 CEP17238.1 - 2.5e-16 59.9 0.0 4.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CEP17238.1 - 2.3e-07 30.1 0.5 5.3e-07 28.9 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP17238.1 - 3.8e-07 29.5 0.3 7.2e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_2 PF13347.1 CEP17238.1 - 0.00012 20.6 37.2 0.00023 19.7 12.9 3.0 1 1 1 2 2 2 2 MFS/sugar transport protein SH3_2 PF07653.12 CEP17238.1 - 0.00037 19.9 0.0 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-C2H2_4 PF13894.1 CEP17239.1 - 1.1e-05 25.3 6.8 0.028 14.7 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP17239.1 - 0.0002 21.5 15.7 0.0058 16.9 1.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP17239.1 - 0.00036 20.6 0.9 0.00036 20.6 0.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain Transferase PF02458.10 CEP17242.1 - 2.5e-57 194.2 0.0 3.9e-57 193.6 0.0 1.3 1 1 0 1 1 1 1 Transferase family SET PF00856.23 CEP17243.1 - 2.4e-25 89.7 0.8 2.4e-25 89.7 0.6 3.5 2 1 0 2 2 2 1 SET domain Lipase_GDSL PF00657.17 CEP17243.1 - 1.1e-22 81.0 0.0 2e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP17243.1 - 1.2e-21 77.6 0.0 2.1e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family N-SET PF11764.3 CEP17243.1 - 8.6e-10 38.7 3.5 8.6e-10 38.7 2.4 4.2 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.17 CEP17243.1 - 2.4e-08 33.4 0.0 1.2e-06 28.0 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17243.1 - 7.6e-06 25.8 0.0 3.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 CEP17243.1 - 0.004 16.4 0.0 0.01 15.1 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated zf-CCHC PF00098.18 CEP17244.1 - 0.0023 17.7 0.3 0.0023 17.7 0.2 3.4 4 0 0 4 4 4 1 Zinc knuckle zf-ribbon_3 PF13248.1 CEP17244.1 - 0.026 13.7 0.9 0.3 10.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CEP17244.1 - 0.029 13.8 0.9 0.14 11.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C4_Topoisom PF01396.14 CEP17244.1 - 0.17 11.4 2.8 0.79 9.2 0.4 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger UPF0167 PF03691.9 CEP17244.1 - 0.17 11.2 2.6 0.2 11.0 1.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) DZR PF12773.2 CEP17244.1 - 0.42 10.4 8.4 0.41 10.5 3.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF164 PF02591.10 CEP17244.1 - 0.57 10.0 5.1 0.46 10.3 0.5 2.5 3 0 0 3 3 3 0 Putative zinc ribbon domain Prok-RING_1 PF14446.1 CEP17244.1 - 0.61 9.8 12.2 0.16 11.7 2.2 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.7 CEP17244.1 - 0.76 9.6 7.4 0.39 10.5 1.8 2.5 2 1 1 3 3 3 0 zinc-ribbons HypA PF01155.14 CEP17244.1 - 1.2 8.8 9.7 1.9 8.1 3.7 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CEP17244.1 - 1.9 8.5 8.4 2 8.4 2.8 3.1 2 1 2 4 4 4 0 Zinc ribbon domain zf-Di19 PF05605.7 CEP17244.1 - 3.6 7.8 12.3 0.28 11.3 3.0 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.24 CEP17244.1 - 6.4 6.5 11.3 8.2 6.2 0.9 3.4 2 1 1 3 3 3 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 CEP17244.1 - 8.9 6.2 9.8 2.5 7.9 2.0 2.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain eIF-5a PF01287.15 CEP17246.1 - 5.3e-26 90.3 0.2 1e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CEP17246.1 - 0.0022 17.6 0.4 0.004 16.8 0.3 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CEP17246.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain RhoGAP PF00620.22 CEP17247.1 - 1.2e-36 125.6 2.2 1.2e-36 125.6 1.5 2.4 2 0 0 2 2 2 1 RhoGAP domain MCC-bdg_PDZ PF10506.4 CEP17247.1 - 0.26 11.1 5.6 0.14 12.0 0.8 2.8 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome USP8_interact PF08941.5 CEP17247.1 - 0.29 10.4 2.6 0.48 9.7 0.2 2.5 2 0 0 2 2 2 0 USP8 interacting FCH PF00611.18 CEP17247.1 - 0.43 10.7 8.1 0.045 13.9 0.9 3.1 4 0 0 4 4 4 0 Fes/CIP4, and EFC/F-BAR homology domain ABC_membrane_2 PF06472.10 CEP17248.1 - 1.8e-95 319.2 1.1 2.4e-95 318.8 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CEP17248.1 - 1.8e-16 60.6 0.0 5.4e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CEP17248.1 - 0.00094 18.4 0.1 0.26 10.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEP17248.1 - 0.0059 16.9 0.1 0.0059 16.9 0.1 2.5 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CEP17248.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP17248.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 CEP17248.1 - 0.019 14.9 3.1 0.026 14.5 0.0 2.4 2 1 1 3 3 3 0 AAA domain PCI PF01399.22 CEP17249.1 - 5e-11 42.8 1.5 1.5e-10 41.3 0.2 2.1 2 0 0 2 2 2 1 PCI domain TMF_DNA_bd PF12329.3 CEP17249.1 - 0.0016 18.2 2.4 0.0016 18.2 1.7 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 CEP17249.1 - 0.0051 15.5 1.3 0.0083 14.8 0.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.1 CEP17249.1 - 0.011 14.9 1.2 0.022 13.9 0.8 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 CEP17249.1 - 0.011 15.7 0.5 0.011 15.7 0.3 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit THOC7 PF05615.8 CEP17249.1 - 0.017 15.4 1.8 0.026 14.7 1.2 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 FliJ PF02050.11 CEP17249.1 - 0.026 14.5 3.6 0.065 13.2 2.5 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein DivIC PF04977.10 CEP17249.1 - 0.051 13.0 2.0 0.089 12.2 0.5 2.0 2 0 0 2 2 2 0 Septum formation initiator RNA_pol_A_CTD PF03118.10 CEP17249.1 - 0.08 12.3 0.1 0.37 10.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Snapin_Pallidin PF14712.1 CEP17249.1 - 0.095 13.0 0.3 0.095 13.0 0.2 2.7 2 1 1 3 3 3 0 Snapin/Pallidin TBPIP PF07106.8 CEP17249.1 - 0.16 11.4 5.3 0.51 9.8 1.3 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF613 PF04764.7 CEP17249.1 - 0.46 10.3 2.3 3 7.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF613) FlaC_arch PF05377.6 CEP17249.1 - 0.46 10.4 3.6 1.2 9.1 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 CEP17249.1 - 0.6 9.0 4.7 0.45 9.4 2.3 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 CEP17252.1 - 5e-51 173.3 0.0 6.9e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17252.1 - 6.8e-34 117.1 0.0 1.1e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP17252.1 - 2e-05 23.7 0.0 3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF1491 PF07372.7 CEP17252.1 - 0.16 11.9 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) DDE_2 PF02914.10 CEP17252.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase IMPDH PF00478.20 CEP17253.1 - 5.8e-138 459.5 4.0 6.8e-138 459.3 2.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CEP17253.1 - 3.3e-14 52.3 0.0 3.8e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CEP17253.1 - 2.8e-10 39.6 0.8 7.4e-10 38.1 0.6 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CEP17253.1 - 4.5e-09 35.9 3.5 1.1e-05 24.7 1.5 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 CEP17253.1 - 0.00013 21.3 2.5 0.0027 17.0 0.1 2.5 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 CEP17253.1 - 0.00051 19.1 0.7 0.00096 18.2 0.1 1.8 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 CEP17253.1 - 0.0031 16.3 0.3 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Aldolase PF01081.14 CEP17253.1 - 0.0032 16.6 0.6 0.0079 15.3 0.0 1.9 2 0 0 2 2 2 1 KDPG and KHG aldolase Perilipin PF03036.11 CEP17254.1 - 1.7e-17 63.3 10.0 2.5e-11 43.0 0.1 2.1 1 1 1 2 2 2 2 Perilipin family FlgN PF05130.7 CEP17254.1 - 0.011 16.0 5.5 0.014 15.6 3.3 1.6 1 1 0 1 1 1 0 FlgN protein BTG PF07742.7 CEP17254.1 - 0.087 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 BTG family YmaF PF12788.2 CEP17254.1 - 0.11 12.6 0.3 11 6.2 0.0 2.6 1 1 1 2 2 2 0 YmaF family Chorismate_synt PF01264.16 CEP17255.1 - 3.6e-132 440.0 0.1 4.2e-132 439.8 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 CEP17255.1 - 0.023 14.3 1.6 0.066 12.8 1.1 1.8 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain GatB_N PF02934.10 CEP17256.1 - 1.9e-108 361.7 0.0 2.4e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CEP17256.1 - 5.4e-38 130.0 0.1 8.9e-38 129.3 0.0 1.4 1 0 0 1 1 1 1 GatB domain RasGAP PF00616.14 CEP17257.1 - 1.5e-26 93.2 0.0 6.8e-26 91.1 0.0 2.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 CEP17257.1 - 1.3e-14 54.3 1.0 5e-14 52.4 0.7 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CEP17257.1 - 0.0086 15.5 0.9 0.034 13.6 0.6 2.0 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT PF02985.17 CEP17257.1 - 0.076 13.1 2.2 9.2 6.6 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat XPG_N PF00752.12 CEP17258.1 - 2.1e-15 56.8 0.0 5.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CEP17258.1 - 9e-14 51.2 0.0 2.6e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CEP17258.1 - 0.00063 19.9 0.0 0.0026 17.9 0.0 2.1 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold ALMT PF11744.3 CEP17259.1 - 5.6e-21 74.6 15.4 1.9e-14 53.1 3.6 2.7 2 1 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 CEP17259.1 - 5.4e-15 55.4 8.4 5.4e-15 55.4 5.8 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 CEP17259.1 - 8.4e-13 47.6 9.6 4.5e-07 28.6 5.3 2.3 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 CEP17259.1 - 3.4e-12 46.4 5.9 1.4e-10 41.1 1.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CEP17259.1 - 7.9e-11 41.4 6.9 7.9e-11 41.4 4.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) CcmD PF04995.9 CEP17259.1 - 0.092 12.4 0.8 0.45 10.2 0.5 2.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF939 PF06081.6 CEP17259.1 - 0.31 10.8 11.3 1.6 8.5 2.1 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF939) adh_short PF00106.20 CEP17260.1 - 6.1e-10 39.2 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CEP17260.1 - 0.0034 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THOC7 PF05615.8 CEP17261.1 - 4.6e-09 36.6 9.6 4.6e-09 36.6 6.7 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 Reo_sigmaC PF04582.7 CEP17261.1 - 0.028 13.5 0.4 0.034 13.3 0.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CENP-Q PF13094.1 CEP17261.1 - 0.21 11.5 16.0 0.024 14.6 7.4 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4613 PF15390.1 CEP17261.1 - 0.36 8.9 4.6 0.43 8.7 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1664 PF07889.7 CEP17261.1 - 1.1 9.0 7.8 0.27 11.0 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4559 PF15112.1 CEP17261.1 - 3.8 6.5 12.8 3.2 6.8 8.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Noelin-1 PF12308.3 CEP17261.1 - 5.1 6.9 6.6 6.1 6.7 1.7 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein Fib_alpha PF08702.5 CEP17261.1 - 9.9 6.2 12.7 4.5 7.4 4.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cupin_8 PF13621.1 CEP17263.1 - 0.026 14.0 0.1 0.047 13.1 0.1 1.3 1 0 0 1 1 1 0 Cupin-like domain MULE PF10551.4 CEP17264.1 - 1.4e-10 41.1 0.1 4.4e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain MULE PF10551.4 CEP17265.1 - 0.0043 17.1 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_4 PF13359.1 CEP17266.1 - 3.3e-18 65.7 0.4 1.8e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.9 CEP17266.1 - 0.00026 20.4 0.0 0.00055 19.3 0.0 1.6 1 0 0 1 1 1 1 Plant transposon protein HMG-CoA_red PF00368.13 CEP17267.1 - 3.8e-160 532.6 10.2 5.5e-160 532.0 7.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 CEP17267.1 - 1.5e-16 60.2 0.9 1.5e-16 60.2 0.6 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CEP17267.1 - 5.3e-11 41.2 6.1 9.3e-11 40.3 4.2 1.3 1 0 0 1 1 1 1 Patched family HPIH PF13323.1 CEP17267.1 - 0.00012 21.8 0.7 0.00037 20.2 0.5 1.9 1 0 0 1 1 1 1 N-terminal domain with HPIH motif zf-SNAP50_C PF12251.3 CEP17268.1 - 1.4e-42 145.3 7.4 2.1e-42 144.7 5.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal PPV_E1_N PF00524.13 CEP17268.1 - 0.27 11.4 3.4 2.2 8.5 0.1 2.9 3 0 0 3 3 3 0 E1 Protein, N terminal domain SET PF00856.23 CEP17269.1 - 3e-17 63.3 0.0 5e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 CEP17269.1 - 4e-05 23.5 0.1 0.00027 20.8 0.0 2.3 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding zf-C3HC4_2 PF13923.1 CEP17270.1 - 7.5e-08 32.2 11.4 1.5e-07 31.3 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP17270.1 - 2.5e-07 30.2 9.4 4.9e-07 29.3 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP17270.1 - 1.2e-06 28.0 12.3 2.4e-06 27.1 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEP17270.1 - 1.9e-06 27.4 12.0 4.9e-06 26.0 8.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRE1 PF08647.6 CEP17270.1 - 3.4e-06 26.9 12.6 3.4e-06 26.9 8.7 6.6 6 1 2 8 8 8 1 BRE1 E3 ubiquitin ligase zf-RING_2 PF13639.1 CEP17270.1 - 1.2e-05 25.0 11.4 2.4e-05 24.0 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 CEP17270.1 - 2.8e-05 23.7 4.3 6.5e-05 22.6 3.0 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Tropomyosin_1 PF12718.2 CEP17270.1 - 0.0057 16.5 22.3 0.0057 16.5 15.5 6.0 5 1 1 6 6 6 1 Tropomyosin like zf-rbx1 PF12678.2 CEP17270.1 - 0.0074 16.3 5.9 0.02 14.9 4.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger T2SF PF00482.18 CEP17270.1 - 0.059 13.2 2.6 0.086 12.7 0.1 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F zf-C3HC4_4 PF15227.1 CEP17270.1 - 0.064 13.1 6.9 0.13 12.1 4.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP17270.1 - 0.17 11.6 6.7 0.54 10.0 4.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CEP17270.1 - 0.35 10.4 10.1 1.6 8.3 6.9 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Reo_sigmaC PF04582.7 CEP17270.1 - 1.4 8.0 9.7 7.1 5.7 0.2 3.6 3 2 0 3 3 3 0 Reovirus sigma C capsid protein Josephin PF02099.12 CEP17271.1 - 3.9e-41 140.3 0.1 8.6e-41 139.1 0.1 1.6 1 0 0 1 1 1 1 Josephin cNMP_binding PF00027.24 CEP17271.1 - 2.6e-37 126.5 1.3 6.7e-20 70.6 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CEP17271.1 - 6.4e-11 41.4 1.3 1.4e-10 40.4 0.9 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit INCA1 PF15142.1 CEP17271.1 - 0.072 12.8 0.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 INCA1 UIM PF02809.15 CEP17271.1 - 0.35 10.5 3.8 0.21 11.2 0.7 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif Metal_resist PF13801.1 CEP17272.1 - 0.18 11.8 0.3 0.94 9.4 0.0 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Acyltransferase PF01553.16 CEP17273.1 - 1.5e-23 82.6 0.0 2.2e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase US2 PF02476.10 CEP17273.1 - 0.086 13.3 0.0 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 US2 family Prd1-P2 PF09214.6 CEP17273.1 - 0.16 10.5 1.5 3.7 5.9 1.1 2.0 2 0 0 2 2 2 0 Bacteriophage Prd1, adsorption protein P2 DNA_alkylation PF08713.6 CEP17274.1 - 0.037 13.5 0.1 0.069 12.6 0.1 1.5 1 1 0 1 1 1 0 DNA alkylation repair enzyme Lyase_8_N PF08124.6 CEP17275.1 - 2e-29 102.4 0.6 3.2e-29 101.8 0.4 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8 PF02278.13 CEP17275.1 - 1.1e-17 64.3 3.4 1.9e-17 63.5 2.3 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_C PF02884.12 CEP17275.1 - 3.8e-05 23.6 0.0 0.00017 21.5 0.0 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain VIT1 PF01988.14 CEP17276.1 - 2e-65 220.2 0.0 2.5e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 VIT family CRC_subunit PF08624.5 CEP17277.1 - 1.1e-39 135.5 0.0 1.9e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.24 CEP17277.1 - 6.1e-20 70.6 49.4 6.3e-09 35.4 10.0 4.3 3 1 1 4 4 4 3 PHD-finger C1_1 PF00130.17 CEP17277.1 - 1.4 8.7 42.6 0.1 12.3 3.7 4.7 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cytochrom_C PF00034.16 CEP17277.1 - 7.1 7.5 9.6 26 5.7 0.0 3.5 3 0 0 3 3 3 0 Cytochrome c Solute_trans_a PF03619.11 CEP17278.1 - 4.6e-20 72.0 9.0 5.7e-20 71.7 4.8 1.8 2 0 0 2 2 2 1 Organic solute transporter Ostalpha DUF2231 PF09990.4 CEP17278.1 - 0.0057 16.9 1.6 0.011 16.0 0.1 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2231) KIAA1328 PF15369.1 CEP17278.1 - 0.85 9.3 4.8 1.2 8.8 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Abhydrolase_6 PF12697.2 CEP17279.1 - 4.9e-13 49.4 0.0 7.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP17279.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP17279.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family CENP-L PF13092.1 CEP17281.1 - 7.1e-11 42.1 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 DUF4269 PF14091.1 CEP17281.1 - 0.063 13.2 0.7 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) GATA PF00320.22 CEP17283.1 - 2.7e-15 55.3 5.3 6.9e-15 54.1 3.7 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-C3HC4_3 PF13920.1 CEP17283.1 - 0.19 11.4 2.1 0.34 10.6 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 CEP17283.1 - 2 8.1 5.9 1.6 8.4 1.3 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain CLTH PF10607.4 CEP17284.1 - 5.8e-41 139.5 0.6 7.9e-41 139.1 0.4 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CEP17284.1 - 1.2e-10 40.7 0.1 6.8e-10 38.3 0.1 2.3 3 0 0 3 3 3 1 LisH His_biosynth PF00977.16 CEP17285.1 - 3.5e-34 118.0 0.0 4.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein HIT PF01230.18 CEP17286.1 - 1e-18 67.6 0.1 1.9e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CEP17286.1 - 3e-06 27.4 0.2 6.8e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.12 CEP17286.1 - 0.045 13.2 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain MAGE PF01454.14 CEP17287.1 - 1.1e-25 90.1 2.8 3.3e-24 85.2 0.8 2.2 1 1 1 2 2 2 2 MAGE family Inhibitor_I71 PF12628.2 CEP17287.1 - 1.1 8.8 5.8 0.43 10.2 0.7 2.1 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor DMAP_binding PF06464.6 CEP17287.1 - 5.7 7.5 8.6 0.7 10.5 1.3 2.5 3 0 0 3 3 3 0 DMAP1-binding Domain NUDIX PF00293.23 CEP17289.1 - 6.4e-20 71.1 0.4 9e-20 70.6 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain ETF_QO PF05187.8 CEP17290.1 - 7.1e-46 154.7 0.0 1.1e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CEP17290.1 - 2.1e-10 40.0 0.2 4.3e-05 22.5 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP17290.1 - 2.7e-08 33.1 0.3 0.00031 19.6 0.9 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CEP17290.1 - 8.5e-07 28.9 0.0 3.2e-06 27.0 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CEP17290.1 - 3.2e-06 26.5 0.0 8.5e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CEP17290.1 - 6.9e-06 25.3 0.0 0.00028 20.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 CEP17290.1 - 2.6e-05 24.5 0.4 0.081 13.3 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEP17290.1 - 6e-05 21.6 0.4 0.00011 20.8 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 CEP17290.1 - 6.8e-05 22.6 0.3 0.00032 20.5 0.2 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEP17290.1 - 0.00013 21.8 0.1 0.00025 20.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 CEP17290.1 - 0.00016 22.0 1.2 0.00041 20.6 0.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Trp_halogenase PF04820.9 CEP17290.1 - 0.00024 19.8 0.1 0.0061 15.2 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.14 CEP17290.1 - 0.00043 19.4 0.1 0.00082 18.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CEP17290.1 - 0.0025 17.9 0.0 0.0075 16.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEP17290.1 - 0.0063 15.4 0.2 0.009 14.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_10 PF13237.1 CEP17290.1 - 0.039 13.7 1.8 0.063 13.0 0.7 1.7 2 0 0 2 2 1 0 4Fe-4S dicluster domain GIDA PF01134.17 CEP17290.1 - 0.23 10.3 0.6 0.32 9.7 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-RING_2 PF13639.1 CEP17291.1 - 3.8e-11 42.6 7.2 5.9e-11 42.0 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP17291.1 - 7.8e-06 25.8 8.0 1.3e-05 25.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP17291.1 - 9.7e-06 25.2 6.4 1.6e-05 24.5 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEP17291.1 - 5e-05 22.8 7.2 9.2e-05 22.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF869 PF05911.6 CEP17291.1 - 0.00015 20.2 14.6 0.00019 19.8 10.1 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) zf-RING_UBOX PF13445.1 CEP17291.1 - 0.00021 20.9 2.9 0.00093 18.8 2.0 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CEP17291.1 - 0.00032 20.7 4.6 0.00067 19.7 3.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEP17291.1 - 0.00038 20.0 9.9 0.00056 19.5 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin_1 PF12718.2 CEP17291.1 - 0.00083 19.2 3.5 0.00083 19.2 2.4 2.8 1 1 1 2 2 2 1 Tropomyosin like zf-RING_6 PF14835.1 CEP17291.1 - 0.0017 18.1 8.0 0.0045 16.7 5.6 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein APG6 PF04111.7 CEP17291.1 - 0.0079 15.2 19.6 0.059 12.4 6.6 2.2 2 0 0 2 2 2 2 Autophagy protein Apg6 Uds1 PF15456.1 CEP17291.1 - 0.016 15.2 9.8 0.016 15.2 6.8 2.9 2 1 1 3 3 3 0 Up-regulated During Septation HR1 PF02185.11 CEP17291.1 - 0.019 14.6 4.9 0.019 14.6 3.4 4.2 3 1 2 5 5 5 0 Hr1 repeat zf-Nse PF11789.3 CEP17291.1 - 0.026 14.0 4.0 0.059 12.8 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CEP17291.1 - 0.09 12.3 4.2 0.17 11.4 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MIF4G_like_2 PF09090.6 CEP17291.1 - 0.55 9.4 12.8 0.04 13.1 4.5 2.1 1 1 1 2 2 2 0 MIF4G like T2SF PF00482.18 CEP17291.1 - 0.55 10.1 1.9 9.6 6.1 0.0 2.4 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F zf-Apc11 PF12861.2 CEP17291.1 - 0.7 9.7 3.8 1.4 8.7 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Fib_alpha PF08702.5 CEP17291.1 - 1.8 8.7 21.1 0.35 10.9 8.7 2.9 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CEP17291.1 - 4.3 6.9 21.0 7.9 6.0 5.1 2.6 1 1 1 2 2 2 0 IncA protein Bacillus_HBL PF05791.6 CEP17291.1 - 8.8 5.6 22.4 0.58 9.5 0.6 3.2 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Med10 PF09748.4 CEP17292.1 - 0.05 13.4 0.3 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Mnd1 PF03962.10 CEP17293.1 - 0.0013 18.4 10.4 0.0013 18.4 7.2 4.0 1 1 3 4 4 4 1 Mnd1 family CALCOCO1 PF07888.6 CEP17293.1 - 0.12 10.6 42.6 0.091 11.0 15.4 2.1 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.6 CEP17293.1 - 0.22 11.4 13.8 2.2 8.2 0.7 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF2353 PF09789.4 CEP17293.1 - 0.78 8.9 43.7 3.5 6.7 25.7 2.9 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) zf-C4H2 PF10146.4 CEP17293.1 - 1.2 9.0 30.0 2 8.4 7.7 2.5 1 1 0 2 2 2 0 Zinc finger-containing protein Reo_sigmaC PF04582.7 CEP17293.1 - 1.6 7.8 15.2 0.94 8.5 2.8 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein zf-RING_2 PF13639.1 CEP17294.1 - 1.8e-06 27.6 8.4 3.9e-06 26.5 5.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEP17294.1 - 0.0013 18.8 4.7 0.0042 17.1 3.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CEP17294.1 - 0.026 14.5 10.4 0.067 13.2 7.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP17294.1 - 0.047 13.4 12.4 0.11 12.2 8.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Citrate_synt PF00285.16 CEP17294.1 - 0.085 11.5 4.2 0.17 10.5 2.9 1.4 1 0 0 1 1 1 0 Citrate synthase NPV_P10 PF05531.7 CEP17294.1 - 1.7 8.9 7.5 22 5.3 1.2 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_3 PF13920.1 CEP17294.1 - 2.3 7.9 10.7 5.2 6.8 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP17294.1 - 4.2 7.1 12.1 0.27 10.9 4.4 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LrgB PF04172.11 CEP17295.1 - 5.4e-27 94.3 7.8 5.4e-27 94.3 5.4 1.9 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.9 CEP17295.1 - 5.9e-10 38.7 3.9 2.2e-09 36.8 2.7 2.1 1 0 0 1 1 1 1 LrgA family DUF2852 PF11014.3 CEP17295.1 - 0.12 12.2 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) CotH PF08757.6 CEP17296.1 - 7.2e-27 94.4 7.0 1.2e-26 93.7 4.9 1.3 1 0 0 1 1 1 1 CotH protein DUF1325 PF07039.6 CEP17297.1 - 1.9e-34 118.0 1.0 2.9e-34 117.4 0.7 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.7 CEP17297.1 - 0.0036 17.4 0.2 3.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Agenet domain TUDOR PF00567.19 CEP17297.1 - 0.0069 16.2 0.0 0.042 13.6 0.0 2.2 2 1 1 3 3 3 1 Tudor domain RabGAP-TBC PF00566.13 CEP17298.1 - 1.6e-44 151.9 1.2 2.5e-44 151.2 0.9 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Herpes_UL32 PF06070.6 CEP17298.1 - 0.036 12.5 3.7 0.05 12.0 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 CDO_I PF05995.7 CEP17299.1 - 2e-33 115.0 0.2 3.4e-26 91.4 0.1 2.2 2 0 0 2 2 2 2 Cysteine dioxygenase type I DUF1637 PF07847.7 CEP17299.1 - 1.3e-06 27.9 0.1 2.5e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1637) SH3_1 PF00018.23 CEP17300.1 - 2.6e-43 145.1 8.7 3.5e-15 55.0 0.3 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.1 CEP17300.1 - 2.9e-40 135.5 9.7 9.1e-14 50.7 0.2 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.12 CEP17300.1 - 1e-32 111.3 0.7 1.9e-10 40.0 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.7 CEP17300.1 - 6.5e-31 105.7 0.1 1.6e-30 104.5 0.1 1.7 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 zf-RING_2 PF13639.1 CEP17300.1 - 1.6e-11 43.8 7.4 3.7e-11 42.6 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEP17300.1 - 3.1e-08 33.5 7.8 5.8e-08 32.6 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP17300.1 - 1e-06 28.2 5.8 1.9e-06 27.4 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH3_3 PF08239.6 CEP17300.1 - 1.6e-06 28.1 4.7 0.16 12.1 0.0 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain zf-C3HC4 PF00097.20 CEP17300.1 - 4.8e-06 26.1 7.0 9.4e-06 25.1 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP17300.1 - 1.1e-05 25.0 6.5 2e-05 24.2 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CEP17300.1 - 0.00021 20.9 4.1 0.00061 19.4 2.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 CEP17300.1 - 0.0023 17.1 1.6 0.0023 17.1 1.1 4.6 4 0 0 4 4 4 1 Rtf2 RING-finger CAF-1_p150 PF11600.3 CEP17300.1 - 0.0048 16.2 50.0 0.0048 16.2 34.7 3.7 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-rbx1 PF12678.2 CEP17300.1 - 0.0068 16.4 2.9 0.021 14.9 2.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CEP17300.1 - 0.009 15.8 8.0 0.019 14.8 5.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CEP17300.1 - 0.096 12.2 2.7 0.22 11.0 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 CEP17300.1 - 0.16 11.8 1.7 0.41 10.5 1.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CEP17300.1 - 1.3 8.6 5.1 2.6 7.6 3.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ALMT PF11744.3 CEP17300.1 - 1.4 7.5 5.8 0.27 9.8 1.1 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter SynMuv_product PF06047.6 CEP17301.1 - 1.7e-47 159.4 3.3 1.7e-47 159.4 2.3 2.3 2 0 0 2 2 2 1 Ras-induced vulval development antagonist Ribosomal_L37 PF08561.5 CEP17302.1 - 8.5e-26 89.3 3.2 1.2e-25 88.8 2.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Ras PF00071.17 CEP17303.1 - 1.4e-49 167.5 0.0 2.7e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Abhydrolase_5 PF12695.2 CEP17303.1 - 1e-14 54.5 0.0 2.4e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Miro PF08477.8 CEP17303.1 - 1.2e-14 54.7 0.0 1e-13 51.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Abhydrolase_3 PF07859.8 CEP17303.1 - 4.6e-13 49.2 0.0 1.2e-12 47.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEP17303.1 - 7.1e-08 31.9 1.0 9.7e-08 31.4 0.0 1.7 2 0 0 2 2 1 1 Prolyl oligopeptidase family RNase_P_pop3 PF08228.6 CEP17303.1 - 1e-07 31.9 0.1 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit Pop3 COesterase PF00135.23 CEP17303.1 - 1.2e-07 30.8 0.1 2.3e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 Carboxylesterase family Arf PF00025.16 CEP17303.1 - 5e-07 29.1 0.0 1.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Abhydrolase_6 PF12697.2 CEP17303.1 - 1.7e-06 28.1 0.0 3.8e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CEP17303.1 - 0.001 17.9 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase PF00151.14 CEP17303.1 - 0.0015 17.7 0.7 0.0026 17.0 0.5 1.3 1 0 0 1 1 1 1 Lipase DUF2305 PF10230.4 CEP17303.1 - 0.007 15.8 0.0 0.007 15.8 0.0 2.0 2 0 0 2 2 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 CEP17303.1 - 0.0086 15.6 0.2 1.3 8.4 0.1 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CEP17303.1 - 0.009 15.6 0.3 0.022 14.3 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein ABC_tran PF00005.22 CEP17303.1 - 0.013 15.7 0.7 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Abhydrolase_2 PF02230.11 CEP17303.1 - 0.015 14.7 7.6 0.082 12.3 0.0 3.3 3 1 1 4 4 3 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 CEP17303.1 - 0.048 13.0 0.0 0.048 13.0 0.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2974) Esterase PF00756.15 CEP17303.1 - 0.11 11.8 1.7 1.2 8.5 0.0 2.8 3 0 0 3 3 3 0 Putative esterase AAA_23 PF13476.1 CEP17303.1 - 0.16 12.2 8.6 1.6 9.0 2.9 2.5 2 0 0 2 2 2 0 AAA domain Gag_spuma PF03276.9 CEP17303.1 - 1.5 7.0 9.9 2.2 6.5 6.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Agouti PF05039.7 CEP17303.1 - 2.2 8.7 5.8 5.1 7.5 4.0 1.6 1 0 0 1 1 1 0 Agouti protein DUF3453 PF11935.3 CEP17304.1 - 6.3e-32 110.8 7.1 6.3e-32 110.8 4.9 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3453) HEAT PF02985.17 CEP17304.1 - 1.1e-06 28.2 0.9 0.11 12.5 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 CEP17304.1 - 8.2e-05 22.8 0.1 0.17 12.1 0.0 3.4 2 0 0 2 2 2 2 HEAT repeats PEHE PF15275.1 CEP17304.1 - 0.0021 18.4 3.8 0.005 17.2 0.0 2.7 2 0 0 2 2 2 1 PEHE domain Arm PF00514.18 CEP17304.1 - 0.022 14.6 0.6 1.3 8.9 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF3388 PF11868.3 CEP17304.1 - 0.069 12.2 1.6 0.49 9.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3388) PIF1 PF05970.9 CEP17305.1 - 5.7e-08 32.0 0.1 1.2e-07 31.0 0.1 1.5 2 0 0 2 2 2 1 PIF1-like helicase DDE_3 PF13358.1 CEP17307.1 - 6.6e-30 103.7 0.0 1.1e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP17307.1 - 5.9e-08 32.8 0.2 1.3e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP17307.1 - 4.1e-06 26.6 1.0 8.8e-06 25.6 0.7 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP17307.1 - 8.1e-05 23.3 0.4 0.00032 21.4 0.0 2.2 2 1 0 2 2 2 1 Homeodomain-like domain DDE_1 PF03184.14 CEP17307.1 - 0.0077 15.3 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 CEP17307.1 - 0.011 14.9 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MULE PF10551.4 CEP17307.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain HTH_23 PF13384.1 CEP17307.1 - 0.068 12.8 0.4 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain rve PF00665.21 CEP17307.1 - 0.075 13.1 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain PH PF00169.24 CEP17308.1 - 9.6e-19 67.5 0.8 9.6e-19 67.5 0.5 2.3 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 CEP17308.1 - 3.8e-17 61.8 0.1 8.5e-17 60.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEP17308.1 - 3.8e-14 52.6 0.4 9.9e-14 51.2 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 CEP17308.1 - 4.6e-14 51.7 0.0 9.9e-14 50.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP17308.1 - 2.9e-13 48.9 0.2 7.7e-13 47.6 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP17308.1 - 1e-09 37.7 0.0 1.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.26 CEP17308.1 - 1.5e-07 31.4 0.0 6.1e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_11 PF15413.1 CEP17308.1 - 9.6e-06 25.8 9.4 4.5e-05 23.6 2.7 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 CEP17308.1 - 0.0025 17.8 0.1 0.015 15.3 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 CEP17308.1 - 0.1 12.6 0.4 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Ste50p, sterile alpha motif ENTH PF01417.15 CEP17309.1 - 7.2e-44 148.6 0.9 1.7e-43 147.4 0.4 1.8 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.11 CEP17309.1 - 7.2e-05 21.6 0.2 0.00011 21.0 0.1 1.3 1 0 0 1 1 1 1 ANTH domain Mod_r PF07200.8 CEP17310.1 - 2.6e-21 76.0 7.2 2.6e-21 76.0 5.0 8.4 6 2 2 8 8 8 1 Modifier of rudimentary (Mod(r)) protein TACC PF05010.9 CEP17310.1 - 7.1e-05 22.6 1.5 7.1e-05 22.6 1.1 5.0 2 1 2 4 4 4 2 Transforming acidic coiled-coil-containing protein (TACC) UEV PF05743.8 CEP17310.1 - 0.0025 17.4 0.3 0.0086 15.7 0.2 2.0 1 0 0 1 1 1 1 UEV domain TspO_MBR PF03073.10 CEP17310.1 - 0.049 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 TspO/MBR family DUF605 PF04652.11 CEP17311.1 - 0.43 9.9 7.8 0.63 9.3 5.4 1.3 1 0 0 1 1 1 0 Vta1 like DDE_3 PF13358.1 CEP17312.1 - 3.4e-29 101.4 0.0 5.9e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP17312.1 - 7e-07 29.9 0.0 1.8e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP17312.1 - 1.3e-06 28.5 0.0 3.3e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CEP17312.1 - 0.00041 20.2 3.5 0.0039 17.1 0.1 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain DDE_1 PF03184.14 CEP17312.1 - 0.0013 17.9 0.7 0.053 12.6 0.0 2.5 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP17312.1 - 0.0042 16.6 2.3 0.08 12.6 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 CEP17312.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Receptor_2B4 PF11465.3 CEP17312.1 - 0.097 12.5 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Pkinase PF00069.20 CEP17314.1 - 2.1e-78 263.0 0.0 2.5e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17314.1 - 5.3e-36 124.0 0.0 7e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP17314.1 - 0.00016 20.7 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CEP17314.1 - 0.00032 20.1 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CEP17314.1 - 0.0086 15.8 0.0 0.056 13.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Methyltransf_23 PF13489.1 CEP17315.1 - 7.8e-20 71.2 0.0 3e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP17315.1 - 5.6e-16 58.8 0.0 9.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP17315.1 - 2.2e-13 50.0 0.0 3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP17315.1 - 3.8e-12 46.7 0.0 6.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP17315.1 - 1.5e-11 44.5 0.0 2.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP17315.1 - 4.4e-07 30.1 0.0 7.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP17315.1 - 3.6e-05 23.7 0.0 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEP17315.1 - 6.2e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 CEP17315.1 - 0.0001 21.1 0.0 0.00019 20.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 CEP17315.1 - 0.00065 18.8 0.0 0.00086 18.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CEP17315.1 - 0.002 17.5 0.1 0.0048 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CEP17315.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 CEP17315.1 - 0.055 12.6 0.0 0.072 12.2 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.7 CEP17315.1 - 0.082 11.7 0.0 0.21 10.3 0.0 1.6 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.1 CEP17315.1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DDE_3 PF13358.1 CEP17317.1 - 3.1e-09 36.7 0.0 4.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sugar_tr PF00083.19 CEP17318.1 - 2.5e-100 336.2 20.5 3.3e-100 335.8 14.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP17318.1 - 2.9e-28 98.6 26.6 1.3e-24 86.5 6.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_9_N PF15420.1 CEP17318.1 - 0.63 9.7 4.4 1.2 8.7 3.0 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF4131 PF13567.1 CEP17318.1 - 1.1 8.6 13.6 3.2 7.1 0.6 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) FKBP_C PF00254.23 CEP17319.1 - 3.7e-33 113.4 0.0 6.9e-33 112.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AhpC-TSA PF00578.16 CEP17321.1 - 9.2e-34 115.8 0.1 1.2e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEP17321.1 - 8.3e-13 48.1 0.0 1.1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CEP17321.1 - 6.7e-10 38.4 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin F-box PF00646.28 CEP17322.1 - 0.025 14.2 0.1 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 F-box domain zf-RVT PF13966.1 CEP17323.1 - 0.00081 19.6 0.4 0.0013 19.0 0.3 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PH_9 PF15410.1 CEP17324.1 - 1.2e-08 35.0 0.0 3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEP17324.1 - 3.8e-06 27.0 0.1 6.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PH domain Ribosomal_L36e PF01158.13 CEP17325.1 - 8.4e-39 131.5 3.6 9.1e-39 131.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 CEP17325.1 - 0.00015 20.9 0.1 0.00016 20.8 0.1 1.1 1 0 0 1 1 1 1 LemA family 4HB_MCP_1 PF12729.2 CEP17325.1 - 0.014 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction HAD PF12710.2 CEP17326.1 - 3.5e-11 43.6 0.0 4.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP17326.1 - 0.014 15.0 0.0 0.058 12.9 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CEP17326.1 - 0.019 14.2 0.0 0.042 13.1 0.0 1.6 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CEP17326.1 - 0.055 13.8 0.0 0.075 13.4 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CEP17326.1 - 0.072 12.2 0.1 15 4.6 0.0 3.1 2 1 0 2 2 2 0 Putative Phosphatase Retro_M PF02813.9 CEP17326.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral M domain MIT PF04212.13 CEP17327.1 - 9.1e-06 25.4 0.3 4.2e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Erf4 PF10256.4 CEP17327.1 - 0.093 12.6 0.7 0.49 10.2 0.5 2.1 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Spermine_synth PF01564.12 CEP17328.1 - 4.2e-90 300.9 0.0 6.8e-90 300.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_2 PF00891.13 CEP17328.1 - 0.0054 15.9 0.2 0.018 14.2 0.1 1.9 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_30 PF05430.6 CEP17328.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.1 CEP17328.1 - 0.01 15.3 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CEP17328.1 - 0.032 14.8 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CEP17328.1 - 0.14 12.6 0.0 0.41 11.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L28e PF01778.12 CEP17329.1 - 6.8e-36 123.2 6.6 8.9e-36 122.8 4.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Use1 PF09753.4 CEP17329.1 - 0.046 13.1 1.2 0.046 13.1 0.8 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF2500 PF10694.4 CEP17329.1 - 0.26 11.2 2.6 0.14 12.1 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) RRM_6 PF14259.1 CEP17330.1 - 1.2e-12 47.5 0.0 2.8e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP17330.1 - 1.2e-09 37.8 0.0 0.00017 21.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP17330.1 - 0.0018 17.8 0.0 4.9 6.8 0.0 3.6 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CEP17331.1 - 2.5e-05 23.5 0.0 8.4e-05 21.8 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17331.1 - 0.039 13.0 0.0 0.16 11.0 0.0 1.8 1 1 1 2 2 2 0 Protein tyrosine kinase PAT1 PF09770.4 CEP17331.1 - 0.13 10.5 10.8 0.17 10.1 7.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Amidohydro_4 PF13147.1 CEP17332.1 - 4.4e-23 82.6 5.1 1.1e-21 78.0 1.6 3.7 3 2 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 CEP17332.1 - 1.9e-14 54.0 0.0 4.5e-13 49.5 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 CEP17332.1 - 2.2e-14 53.0 2.1 4.6e-11 42.3 0.3 2.8 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CEP17332.1 - 4.8e-12 45.8 0.0 1.2e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family vMSA PF00695.14 CEP17332.1 - 0.34 10.0 0.3 0.62 9.2 0.2 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus IF4E PF01652.13 CEP17335.1 - 3.1e-39 134.1 2.2 4.1e-39 133.7 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Oxysterol_BP PF01237.13 CEP17336.1 - 7.6e-87 291.0 0.0 9.8e-87 290.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein ADH_N PF08240.7 CEP17337.1 - 1e-17 63.8 2.5 1.8e-17 63.0 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP17337.1 - 1.1e-14 54.0 0.0 1.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP17337.1 - 0.019 15.8 0.0 0.029 15.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEP17337.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.17 CEP17338.1 - 9.6e-37 124.4 0.0 1.3e-14 53.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17338.1 - 1.1e-23 82.9 0.2 1.5e-08 34.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP17338.1 - 4.1e-22 77.7 0.0 2.6e-07 30.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP17338.1 - 1.7e-05 24.4 0.0 0.35 10.6 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CEP17338.1 - 5.4e-05 22.8 0.3 0.5 10.1 0.0 3.0 2 1 1 3 3 3 2 Limkain b1 RRM_3 PF08777.6 CEP17338.1 - 0.00088 19.0 0.1 1.1 9.1 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif NosL PF05573.7 CEP17338.1 - 0.064 12.9 0.2 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 NosL Zn_clus PF00172.13 CEP17339.1 - 0.0013 18.5 11.7 0.003 17.4 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.5 CEP17339.1 - 0.054 13.5 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 PAS fold Rib_5-P_isom_A PF06026.9 CEP17340.1 - 2e-58 196.5 0.1 2.5e-58 196.2 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CEP17340.1 - 0.0024 17.5 0.2 0.72 9.4 0.0 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.8 CEP17340.1 - 0.048 12.5 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Linker_histone PF00538.14 CEP17341.1 - 9.1e-21 73.7 0.5 2.3e-20 72.4 0.3 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF126 PF01989.11 CEP17341.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF126 TFIIA PF03153.8 CEP17341.1 - 1.2 8.9 22.8 1.6 8.5 15.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S5 PF00333.15 CEP17342.1 - 1.2e-27 95.4 1.3 2.3e-27 94.5 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CEP17342.1 - 1e-22 79.2 0.1 1.8e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Carn_acyltransf PF00755.15 CEP17343.1 - 1.6e-186 620.9 0.2 1.8e-186 620.7 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Phage_T4_Gp30_7 PF06919.6 CEP17343.1 - 0.033 14.1 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Phage Gp30.7 protein Mito_carr PF00153.22 CEP17344.1 - 2.1e-71 235.6 3.7 1.8e-23 82.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C65 PF10275.4 CEP17347.1 - 0.00027 20.3 0.3 0.00027 20.3 0.2 1.7 2 0 0 2 2 2 1 Peptidase C65 Otubain OTU PF02338.14 CEP17347.1 - 0.0069 16.9 0.0 0.021 15.4 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease AAA_11 PF13086.1 CEP17347.1 - 0.09 12.3 0.8 0.14 11.6 0.6 1.2 1 0 0 1 1 1 0 AAA domain RRM_6 PF14259.1 CEP17348.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.21 CEP17349.1 - 4.4e-19 67.9 1.3 5.1e-19 67.7 0.2 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4085 PF13315.1 CEP17349.1 - 0.0075 15.6 0.9 0.0075 15.6 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4085) Foamy_virus_ENV PF03408.9 CEP17349.1 - 0.021 12.3 0.5 0.027 12.0 0.3 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein Cucumo_2B PF03263.8 CEP17349.1 - 0.072 13.3 2.1 0.17 12.1 1.4 1.6 1 0 0 1 1 1 0 Cucumovirus protein 2B Hairpins PF04877.7 CEP17349.1 - 0.24 10.7 1.7 3 7.1 0.2 2.0 2 0 0 2 2 2 0 HrpZ zf-RVT PF13966.1 CEP17350.1 - 0.0015 18.8 1.5 0.0038 17.5 1.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Transposase_31 PF04754.7 CEP17351.1 - 0.00038 19.8 0.5 0.01 15.2 0.0 2.1 1 1 1 2 2 2 2 Putative transposase, YhgA-like DUF3284 PF11687.3 CEP17351.1 - 0.045 13.4 0.2 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3284) DUF2887 PF11103.3 CEP17351.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) Gelsolin PF00626.17 CEP17352.1 - 1.8e-38 130.1 1.1 4.2e-14 51.9 0.0 3.5 4 0 0 4 4 4 3 Gelsolin repeat DXP_synthase_N PF13292.1 CEP17352.1 - 0.057 12.3 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF1752 PF08550.5 CEP17353.1 - 2.1e-10 40.0 0.4 4.2e-10 39.0 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ABC_tran_2 PF12848.2 CEP17353.1 - 0.0036 17.1 0.3 0.0085 15.9 0.2 1.6 1 0 0 1 1 1 1 ABC transporter YL1 PF05764.8 CEP17353.1 - 0.011 15.3 11.8 0.018 14.6 8.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Rho_Binding PF08912.6 CEP17353.1 - 0.022 15.0 1.8 0.022 15.0 1.2 2.0 2 0 0 2 2 2 0 Rho Binding Mac PF12464.3 CEP17353.1 - 0.2 11.6 1.8 1.3 9.0 1.3 2.2 1 1 0 1 1 1 0 Maltose acetyltransferase Nop14 PF04147.7 CEP17353.1 - 1.7 6.5 17.8 0.14 10.1 9.2 1.4 2 0 0 2 2 2 0 Nop14-like family SURF2 PF05477.6 CEP17353.1 - 2.7 7.0 12.6 0.28 10.2 5.8 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) RR_TM4-6 PF06459.7 CEP17353.1 - 4.3 7.1 8.3 1.1 9.0 3.4 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Cyclin PF08613.6 CEP17354.1 - 3.6e-16 59.9 0.2 3.6e-16 59.9 0.1 3.5 4 1 0 4 4 4 1 Cyclin Cyclin_N PF00134.18 CEP17354.1 - 1.5e-06 27.7 0.1 1.5e-06 27.7 0.0 4.7 6 0 0 6 6 6 1 Cyclin, N-terminal domain CDP-OH_P_transf PF01066.16 CEP17355.1 - 9.5e-18 64.3 6.7 9.5e-18 64.3 4.7 2.5 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase CorA PF01544.13 CEP17357.1 - 0.01 14.9 1.7 0.012 14.6 1.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2076 PF09849.4 CEP17357.1 - 0.1 12.6 4.9 0.13 12.2 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cytochrome_C554 PF13435.1 CEP17358.1 - 0.054 13.5 0.1 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c554 and c-prime DDE_3 PF13358.1 CEP17359.1 - 6.6e-23 81.0 0.0 8.2e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP17359.1 - 0.0012 18.8 0.0 0.0027 17.8 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.12 CEP17360.1 - 0.0016 18.4 0.1 0.012 15.6 0.0 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein Cytochrom_C550 PF14495.1 CEP17360.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain Ribosomal_S6 PF01250.12 CEP17362.1 - 8e-16 57.6 0.0 9.3e-16 57.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 HTH_Tnp_Tc3_2 PF01498.13 CEP17364.1 - 1.1e-07 31.8 0.1 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Transposase RabGAP-TBC PF00566.13 CEP17365.1 - 4.1e-33 114.6 4.6 1.4e-27 96.5 0.1 3.1 3 0 0 3 3 3 2 Rab-GTPase-TBC domain DUF2141 PF09912.4 CEP17366.1 - 0.028 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) GPI-anchored PF10342.4 CEP17366.1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TPR_11 PF13414.1 CEP17367.1 - 4e-10 39.1 0.0 7.2e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CEP17367.1 - 1.5e-08 33.8 0.0 0.0068 16.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP17367.1 - 4.1e-08 32.4 0.0 0.00067 19.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP17367.1 - 7.7e-08 32.5 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP17367.1 - 7.5e-05 23.0 0.1 0.3 11.8 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP17367.1 - 0.00011 22.7 0.0 0.0003 21.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP17367.1 - 0.0034 17.0 0.0 0.41 10.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP17367.1 - 0.015 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat HPD PF05044.7 CEP17367.1 - 0.034 13.8 0.1 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeo-prospero domain TPR_7 PF13176.1 CEP17367.1 - 0.04 13.7 0.0 0.6 10.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCHC PF00098.18 CEP17368.1 - 3.5e-05 23.5 1.1 3.5e-05 23.5 0.8 1.8 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 CEP17368.1 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein WGR PF05406.10 CEP17368.1 - 0.063 13.2 0.1 2 8.4 0.0 2.2 2 0 0 2 2 2 0 WGR domain B PF02216.11 CEP17368.1 - 0.064 13.0 0.1 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 B domain Histone PF00125.19 CEP17369.1 - 5.1e-24 84.1 0.3 7e-24 83.7 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEP17369.1 - 6.7e-07 29.2 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CEP17369.1 - 0.00016 21.8 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CEP17370.1 - 1.2e-25 89.4 0.0 1.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEP17370.1 - 2.4e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAGA-Tad1 PF12767.2 CEP17371.1 - 0.0092 15.6 7.6 0.012 15.3 5.2 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DHQS PF01959.11 CEP17371.1 - 0.063 11.9 2.0 0.08 11.6 1.4 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) Histone PF00125.19 CEP17372.1 - 1.9e-15 56.7 0.2 2.3e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEP17372.1 - 2.5e-05 24.3 0.1 3.5e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CEP17372.1 - 5.1e-05 23.1 0.2 7.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CEP17372.1 - 0.00019 21.3 0.1 0.00035 20.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CEP17372.1 - 0.0091 15.2 0.0 0.0091 15.2 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CEP17372.1 - 0.049 13.3 0.1 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 CEP17372.1 - 0.13 12.6 0.1 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CEP17373.1 - 1.4e-31 108.4 0.4 2.1e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEP17373.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CEP17373.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CEP17373.1 - 0.014 14.6 1.1 0.023 13.9 0.8 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CEP17373.1 - 0.019 14.6 0.1 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2462 PF09495.5 CEP17374.1 - 2.7e-12 47.2 13.5 2.7e-12 47.2 9.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) Rho_Binding PF08912.6 CEP17374.1 - 0.12 12.6 4.2 0.091 13.0 2.1 1.5 1 1 0 1 1 1 0 Rho Binding Fibrillarin PF01269.12 CEP17375.1 - 1.3e-111 370.9 0.0 1.7e-111 370.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CEP17375.1 - 5.3e-05 22.8 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CEP17375.1 - 0.00095 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEP17375.1 - 0.022 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) INTS2 PF14750.1 CEP17377.1 - 8.3e-75 252.0 11.3 1.8e-74 250.9 7.9 1.4 1 1 0 1 1 1 1 Integrator complex subunit 2 DnaJ PF00226.26 CEP17378.1 - 2.1e-23 81.8 1.3 2.1e-23 81.8 0.9 1.9 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.6 CEP17378.1 - 1.7e-20 73.2 0.1 1.7e-20 73.2 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 CEP17378.1 - 0.017 15.0 0.1 0.15 12.0 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat PGM_PMM_I PF02878.11 CEP17379.1 - 1.9e-18 66.2 0.0 1.8e-08 33.9 0.0 3.3 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CEP17379.1 - 2.1e-14 53.7 0.4 3e-13 49.9 0.0 3.0 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CEP17379.1 - 2.1e-12 46.8 0.2 5.6e-12 45.4 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 CEP17379.1 - 0.0097 15.9 0.4 0.033 14.2 0.2 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III G3P_antiterm PF04309.7 CEP17379.1 - 0.12 11.3 0.0 7.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Ribosomal_L7Ae PF01248.21 CEP17380.1 - 1.7e-26 91.5 0.2 2.8e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CEP17380.1 - 0.00058 19.7 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 BAR PF03114.13 CEP17381.1 - 1.8e-39 135.6 4.6 1.4e-23 83.5 0.1 2.1 1 1 1 2 2 2 2 BAR domain Arfaptin PF06456.8 CEP17381.1 - 0.00033 20.0 1.8 0.00089 18.6 0.1 2.0 2 0 0 2 2 2 1 Arfaptin-like domain Myb_DNA-bind_5 PF13873.1 CEP17383.1 - 0.091 12.6 2.2 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.18 CEP17384.1 - 1.2e-07 31.2 4.6 4.1e-07 29.6 3.2 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 CEP17384.1 - 0.32 10.7 4.8 0.32 10.6 2.3 1.8 1 1 0 1 1 1 0 Zinc knuckle DUF4051 PF13260.1 CEP17384.1 - 9.3 5.6 5.9 5.4 6.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) CAP_GLY PF01302.20 CEP17385.1 - 5.7e-19 67.5 0.2 1.3e-18 66.4 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain Sel1 PF08238.7 CEP17385.1 - 1.3e-16 60.5 10.1 0.0068 17.0 0.2 5.7 5 0 0 5 5 5 5 Sel1 repeat BTB PF00651.26 CEP17385.1 - 2e-10 40.6 0.1 5.4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain CS PF04969.11 CEP17385.1 - 2e-10 41.0 0.1 7.2e-10 39.2 0.1 2.0 1 0 0 1 1 1 1 CS domain TPR_12 PF13424.1 CEP17385.1 - 0.024 14.5 0.7 14 5.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 CEP17386.1 - 1.3e-21 76.6 0.3 2.4e-21 75.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain VHS PF00790.14 CEP17387.1 - 8.1e-16 57.9 0.3 2.5e-15 56.3 0.2 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CEP17387.1 - 2.2e-05 24.3 0.4 2.2e-05 24.3 0.3 3.1 2 2 0 2 2 2 1 GAT domain Glyco_transf_10 PF00852.14 CEP17388.1 - 3.3e-54 183.7 3.6 4.4e-54 183.3 2.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Glyco_trans_1_2 PF13524.1 CEP17388.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 CDC45 PF02724.9 CEP17389.1 - 7.2e-180 599.0 0.3 7.2e-180 599.0 0.2 2.7 3 0 0 3 3 3 1 CDC45-like protein GCFC PF07842.7 CEP17389.1 - 4.6e-72 242.6 23.2 9.4e-72 241.6 16.1 1.5 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 CEP17389.1 - 9e-14 50.9 1.8 2.6e-13 49.4 1.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CEP17389.1 - 7.7e-07 28.8 1.2 2.6e-06 27.1 0.9 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site DHH PF01368.15 CEP17389.1 - 0.014 15.0 0.6 0.042 13.4 0.4 1.7 1 0 0 1 1 1 0 DHH family AAA_23 PF13476.1 CEP17389.1 - 0.36 11.1 7.4 1 9.6 5.1 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 CEP17390.1 - 1.8e-25 87.8 0.7 6.3e-08 32.2 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CEP17390.1 - 0.067 11.3 0.1 0.15 10.1 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Glycos_transf_1 PF00534.15 CEP17391.1 - 2.6e-21 75.8 0.0 4.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CEP17391.1 - 1.1e-09 38.5 0.0 2.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CEP17391.1 - 0.00034 20.8 0.0 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1817 PF08847.6 CEP17391.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1817) Fic_N PF13784.1 CEP17392.1 - 0.048 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Fic/DOC family N-terminal Cor1 PF04803.7 CEP17392.1 - 0.054 13.2 2.1 0.066 12.9 0.6 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region YxiJ PF14176.1 CEP17392.1 - 0.056 13.5 1.3 0.1 12.7 0.7 1.6 1 1 0 1 1 1 0 YxiJ-like protein Glyco_hydro_4C PF11975.3 CEP17392.1 - 0.1 12.3 1.3 0.14 11.9 0.9 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Cob_adeno_trans PF01923.13 CEP17392.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Astro_capsid PF03115.9 CEP17392.1 - 0.17 10.0 1.1 0.22 9.7 0.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor polyprenyl_synt PF00348.12 CEP17393.1 - 1.1e-52 178.5 0.0 1.3e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase adh_short_C2 PF13561.1 CEP17394.1 - 0.0098 15.6 0.0 0.0098 15.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2046 PF09755.4 CEP17396.1 - 1.3e-29 103.1 26.2 1.3e-29 103.1 18.2 1.9 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) YbaB_DNA_bd PF02575.11 CEP17396.1 - 0.028 14.3 2.0 0.028 14.3 1.4 3.2 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family DUF4349 PF14257.1 CEP17396.1 - 0.032 13.4 9.5 0.022 14.0 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Maelstrom PF13017.1 CEP17396.1 - 0.23 10.9 6.5 0.36 10.2 4.5 1.2 1 0 0 1 1 1 0 piRNA pathway germ-plasm component DUF2513 PF10711.4 CEP17396.1 - 5.6 7.1 9.7 3.3 7.8 1.9 2.4 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) Peptidase_S8 PF00082.17 CEP17397.1 - 8.4e-57 192.4 0.2 1.9e-56 191.3 0.0 1.7 2 0 0 2 2 2 1 Subtilase family TPPII PF12580.3 CEP17397.1 - 5.4e-37 127.0 0.2 8.1e-37 126.4 0.1 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II DUF2533 PF10752.4 CEP17398.1 - 0.43 10.9 4.1 1.6 9.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Sel1 PF08238.7 CEP17399.1 - 5.7e-136 440.0 58.2 1.8e-11 44.2 0.0 15.2 15 0 0 15 15 15 15 Sel1 repeat TPR_6 PF13174.1 CEP17399.1 - 0.0005 20.3 19.6 8.2 7.1 0.1 9.7 12 1 0 12 12 12 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP17399.1 - 0.016 15.3 17.7 25 5.3 0.0 9.4 10 1 0 11 11 11 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP17399.1 - 0.079 12.6 40.7 0.52 9.9 0.4 9.5 2 2 7 11 11 11 0 TPR repeat MIT PF04212.13 CEP17399.1 - 0.13 12.1 11.5 0.77 9.6 0.1 6.4 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain Ribosomal_S24e PF01282.14 CEP17401.1 - 1.5e-35 120.8 0.6 2.1e-35 120.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e SpoU_methylase PF00588.14 CEP17402.1 - 6.2e-35 120.1 0.0 3.2e-34 117.8 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 CEP17402.1 - 5.4e-14 52.1 0.0 1.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding TcdA_TcdB_pore PF12920.2 CEP17402.1 - 0.028 12.3 0.2 0.23 9.3 0.0 1.9 2 0 0 2 2 2 0 TcdA/TcdB pore forming domain RAI16-like PF10257.4 CEP17403.1 - 1.7e-52 178.4 0.9 3.1e-52 177.6 0.6 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FTA4 PF13093.1 CEP17404.1 - 3.3 7.0 21.4 0.21 10.9 3.5 2.2 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Orthopox_A5L PF06193.6 CEP17404.1 - 5.7 6.8 17.6 0.15 11.9 4.2 2.4 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like CS PF04969.11 CEP17405.1 - 0.075 13.5 1.1 0.15 12.6 0.1 1.9 2 1 0 2 2 2 0 CS domain Nipped-B_C PF12830.2 CEP17405.1 - 0.088 12.4 0.1 0.096 12.3 0.1 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Topoisom_I_N PF02919.10 CEP17406.1 - 1.4e-96 321.9 2.9 1.4e-96 321.9 2.0 2.8 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CEP17406.1 - 1.4e-84 282.8 7.4 1.4e-84 282.8 5.2 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CEP17406.1 - 1.7e-32 110.8 1.0 4.6e-32 109.4 0.7 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain Y_phosphatase2 PF03162.8 CEP17407.1 - 7.4e-59 197.7 0.2 1.4e-58 196.9 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CEP17407.1 - 5e-09 36.6 0.0 1.4e-08 35.1 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CEP17407.1 - 8.7e-06 25.3 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP17407.1 - 0.00029 20.2 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 CEP17407.1 - 0.027 13.2 0.0 0.053 12.2 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain GTP_EFTU PF00009.22 CEP17408.1 - 6.2e-53 179.0 0.1 1.2e-52 178.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CEP17408.1 - 6.4e-26 90.0 0.0 1.8e-25 88.5 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CEP17408.1 - 8e-20 70.5 0.1 7.2e-19 67.4 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CEP17408.1 - 1.6e-10 40.8 0.1 5e-10 39.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 CEP17408.1 - 6.1e-06 25.7 0.1 0.0017 17.8 0.0 2.9 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 CEP17408.1 - 0.0023 17.8 0.0 0.0068 16.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CEP17408.1 - 0.1 11.6 0.0 0.62 9.1 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Septin PF00735.13 CEP17409.1 - 2.4e-106 354.8 0.1 4.4e-106 354.0 0.1 1.4 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 CEP17409.1 - 1.5e-07 31.0 0.1 2.9e-06 26.8 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP17409.1 - 3.2e-07 30.2 0.0 6.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP17409.1 - 3.6e-06 26.2 0.1 8.3e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 CEP17409.1 - 0.00023 20.5 0.1 0.00067 19.0 0.1 1.8 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP17409.1 - 0.0011 19.4 0.2 0.004 17.6 0.1 2.0 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 CEP17409.1 - 0.0017 18.4 0.8 0.0074 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain IIGP PF05049.8 CEP17409.1 - 0.0025 16.7 0.0 0.0048 15.7 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.7 CEP17409.1 - 0.0026 16.9 0.0 0.0061 15.7 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 CEP17409.1 - 0.0066 15.9 0.2 0.02 14.3 0.1 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 CEP17409.1 - 0.011 15.9 0.7 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 CEP17409.1 - 0.013 14.9 0.1 0.042 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.21 CEP17409.1 - 0.014 14.8 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AIG1 PF04548.11 CEP17409.1 - 0.017 14.2 1.7 0.017 14.2 0.1 1.8 2 0 0 2 2 2 0 AIG1 family IstB_IS21 PF01695.12 CEP17409.1 - 0.02 14.2 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 CEP17409.1 - 0.022 14.3 2.1 0.023 14.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CEP17409.1 - 0.026 14.3 3.6 1.7 8.4 0.1 3.2 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.17 CEP17409.1 - 0.037 14.1 0.2 0.14 12.3 0.1 2.1 1 1 1 2 2 2 0 RNA helicase AAA_33 PF13671.1 CEP17409.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEP17409.1 - 0.065 13.2 0.3 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 CEP17409.1 - 0.084 11.7 0.2 0.18 10.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 CEP17409.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CEP17409.1 - 0.12 11.9 0.1 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 CEP17409.1 - 0.22 11.0 3.4 2.2 7.7 0.3 3.0 3 1 0 4 4 4 0 Conserved hypothetical ATP binding protein Fzo_mitofusin PF04799.8 CEP17409.1 - 0.94 8.8 4.9 0.18 11.1 0.3 2.0 3 0 0 3 3 3 0 fzo-like conserved region PDEase_I PF00233.14 CEP17410.1 - 1.6e-50 172.0 6.9 2.6e-50 171.4 4.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CEP17410.1 - 2e-08 34.2 1.0 2e-08 34.2 0.7 2.1 2 1 0 2 2 2 1 HD domain UNC45-central PF11701.3 CEP17410.1 - 0.0071 16.0 1.6 3.8 7.1 0.1 2.6 2 2 0 2 2 2 2 Myosin-binding striated muscle assembly central RGS PF00615.14 CEP17411.1 - 2.4e-19 69.5 0.2 4.5e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2370 PF10176.4 CEP17412.1 - 7.4e-70 234.9 0.3 7.4e-70 234.9 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) PS_Dcarbxylase PF02666.10 CEP17413.1 - 1e-53 181.6 0.0 1.6e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CEP17413.1 - 3.4e-27 94.1 0.5 1.2e-14 53.8 0.1 3.0 2 1 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 CEP17413.1 - 0.00017 21.0 0.1 0.8 9.2 0.0 2.7 2 0 0 2 2 2 2 CEP76 C2 domain PepSY_2 PF13670.1 CEP17413.1 - 0.026 14.4 0.0 0.1 12.4 0.0 2.0 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain TFIIA PF03153.8 CEP17413.1 - 0.9 9.3 14.3 0.22 11.3 4.7 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LRR_6 PF13516.1 CEP17415.1 - 4.4e-05 23.1 16.7 1.1 9.5 0.0 8.8 10 1 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.28 CEP17415.1 - 0.057 13.4 16.6 27 5.3 0.0 7.7 8 2 0 8 8 8 0 Leucine Rich Repeat STAS_2 PF13466.1 CEP17415.1 - 0.064 13.2 0.1 0.56 10.2 0.0 2.6 3 1 0 3 3 3 0 STAS domain LRR_4 PF12799.2 CEP17415.1 - 0.19 11.3 20.1 4.3 7.0 0.1 6.8 4 2 3 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP17415.1 - 4.4 7.1 22.6 4.6 7.0 0.4 5.8 5 1 0 5 5 5 0 Leucine rich repeat Aldo_ket_red PF00248.16 CEP17417.1 - 7.9e-54 182.3 0.0 9.7e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1394 PF07159.7 CEP17418.1 - 5.1e-75 252.4 0.6 6.3e-75 252.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Ras PF00071.17 CEP17419.1 - 4.1e-49 166.0 0.4 6.4e-49 165.4 0.3 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CEP17419.1 - 2.1e-15 57.2 0.1 6.9e-15 55.5 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CEP17419.1 - 8.7e-05 22.0 0.0 0.00018 21.0 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CEP17419.1 - 0.0002 20.6 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-CCHC_6 PF15288.1 CEP17421.1 - 0.011 15.3 0.2 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Mdv1 PF11542.3 CEP17421.1 - 0.076 12.9 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial division protein 1 Abhydrolase_6 PF12697.2 CEP17422.1 - 3.4e-35 121.9 0.0 5.8e-35 121.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP17422.1 - 2.4e-20 73.0 0.0 6e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP17422.1 - 2.9e-16 59.5 0.0 4.2e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEP17422.1 - 4.9e-08 32.8 0.0 7.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 CEP17422.1 - 4.3e-05 23.2 0.0 8.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 CEP17422.1 - 0.00031 19.3 0.0 0.079 11.4 0.0 2.1 2 0 0 2 2 2 2 Ndr family Thioesterase PF00975.15 CEP17422.1 - 0.00037 20.7 0.0 0.00058 20.1 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.2 CEP17422.1 - 0.00073 18.4 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydro_lipase PF04083.11 CEP17422.1 - 0.0036 16.6 0.3 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Esterase PF00756.15 CEP17422.1 - 0.0037 16.7 0.0 0.0065 15.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Peptidase_S10 PF00450.17 CEP17422.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.3 1 1 0 1 1 1 0 Serine carboxypeptidase PAF-AH_p_II PF03403.8 CEP17422.1 - 0.066 11.4 0.1 4.3 5.5 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 CEP17422.1 - 0.068 12.7 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3141 PF11339.3 CEP17422.1 - 0.12 10.6 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) MIP-T3 PF10243.4 CEP17423.1 - 1 7.7 43.3 1.6 7.1 30.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 CEP17423.1 - 1.9 7.9 22.2 3.4 7.1 15.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Zip PF02535.17 CEP17423.1 - 6.6 5.6 8.3 0.67 8.9 2.6 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter UQ_con PF00179.21 CEP17424.1 - 1.6e-47 160.4 0.0 1.8e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEP17424.1 - 3.5e-05 23.5 0.0 4.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CEP17424.1 - 0.011 15.6 0.1 0.014 15.3 0.0 1.4 1 1 0 1 1 1 0 RWD domain BRE PF06113.7 CEP17424.1 - 0.017 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) PRP3 PF08572.5 CEP17425.1 - 1.9e-69 233.4 10.1 3.7e-69 232.5 7.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CEP17425.1 - 9.1e-37 125.5 0.2 2.1e-36 124.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) YfcL PF08891.6 CEP17425.1 - 0.085 12.8 0.6 0.25 11.3 0.4 1.8 1 0 0 1 1 1 0 YfcL protein Ribosomal_L44 PF00935.14 CEP17426.1 - 1.4e-35 121.1 9.7 2.1e-35 120.5 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 XPG_I PF00867.13 CEP17427.1 - 4.8e-23 81.0 0.1 1.4e-22 79.4 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CEP17427.1 - 6.5e-20 71.2 0.0 1.8e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain TPR_1 PF00515.23 CEP17427.1 - 0.00056 19.4 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP17427.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEP17427.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 TPR repeat DUF1364 PF07102.7 CEP17427.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) TPR_16 PF13432.1 CEP17427.1 - 0.14 12.8 0.0 0.33 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.1 CEP17428.1 - 0.0066 16.5 1.8 0.0074 16.4 0.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain PAT1 PF09770.4 CEP17428.1 - 0.054 11.7 17.3 0.066 11.4 12.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UBA_3 PF09288.5 CEP17428.1 - 0.13 11.8 1.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain TFIIA PF03153.8 CEP17428.1 - 0.53 10.1 12.0 0.81 9.5 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 CEP17428.1 - 8 5.7 12.6 0.28 10.5 0.5 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_hydro_9 PF00759.14 CEP17429.1 - 2.4e-86 290.3 20.4 2.4e-86 290.3 14.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 zf-RING_2 PF13639.1 CEP17429.1 - 0.00015 21.4 26.5 0.002 17.9 5.6 3.3 3 0 0 3 3 3 2 Ring finger domain IBR PF01485.16 CEP17429.1 - 0.00016 21.4 32.4 0.00031 20.5 9.1 4.6 2 1 1 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 CEP17429.1 - 0.0032 17.0 6.6 0.0032 17.0 4.6 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP17429.1 - 0.12 12.1 27.5 0.017 14.8 6.3 3.2 3 0 0 3 3 3 0 zinc-RING finger domain PBP1_TM PF14812.1 CEP17429.1 - 1.7 8.9 8.2 3.5 7.9 1.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C3HC4_2 PF13923.1 CEP17430.1 - 9.4e-09 35.1 10.4 1.8e-08 34.2 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP17430.1 - 1.4e-07 31.0 9.2 2.9e-07 30.0 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP17430.1 - 3.3e-07 30.0 9.2 7.2e-07 28.9 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP17430.1 - 8.5e-07 28.5 5.0 1.5e-06 27.7 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP17430.1 - 9.3e-06 25.2 6.6 2e-05 24.2 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.15 CEP17430.1 - 0.00023 20.6 9.3 0.00071 19.0 6.5 1.9 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 CEP17430.1 - 0.0008 19.2 8.1 0.0027 17.5 5.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP17430.1 - 0.01 15.5 5.8 0.033 13.8 4.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 CEP17430.1 - 0.013 14.9 3.0 0.036 13.5 2.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 CEP17430.1 - 0.024 14.4 1.8 0.05 13.4 1.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CEP17430.1 - 0.027 14.5 4.8 0.067 13.3 3.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 CEP17430.1 - 0.057 13.3 1.1 0.14 12.0 0.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger DdrB PF12747.2 CEP17430.1 - 0.14 11.8 1.2 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 DdrB-like protein FYDLN_acid PF09538.5 CEP17430.1 - 3.5 8.2 8.7 0.12 12.9 0.8 2.4 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) DUF500 PF04366.7 CEP17431.1 - 8.3e-46 154.5 0.4 1.5e-45 153.7 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_9 PF14604.1 CEP17431.1 - 3.7e-17 61.6 0.0 7.1e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEP17431.1 - 8.7e-17 60.2 0.5 1.9e-16 59.1 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CEP17431.1 - 6.9e-12 44.6 0.0 1.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3605 PF12239.3 CEP17432.1 - 2.6e-25 89.0 3.4 7.8e-24 84.3 2.4 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) CM_2 PF01817.16 CEP17433.1 - 1.4e-07 31.5 0.7 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 2 Chorismate mutase type II Metallothio_Pro PF02069.11 CEP17434.1 - 0.052 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic metallothionein TFIIA PF03153.8 CEP17435.1 - 3.7 7.3 17.6 5.6 6.7 12.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-HC5HC2H_2 PF13832.1 CEP17436.1 - 4.4e-34 116.7 15.6 8.6e-34 115.8 7.5 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CEP17436.1 - 3.3e-26 91.2 8.7 3.3e-26 91.2 6.0 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 CEP17436.1 - 3.1e-17 63.2 24.8 6.7e-17 62.1 14.4 4.6 3 2 1 4 4 4 2 Enhancer of polycomb-like Bromodomain PF00439.20 CEP17436.1 - 3.1e-17 62.2 0.6 9.8e-17 60.6 0.5 1.9 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 CEP17436.1 - 1.2e-14 53.3 3.5 1.2e-14 53.3 2.4 2.6 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 CEP17436.1 - 3.5e-11 42.6 23.2 1e-09 37.8 4.2 2.9 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.12 CEP17436.1 - 4.3e-06 26.8 0.9 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 PWWP domain Prok-RING_1 PF14446.1 CEP17436.1 - 0.0062 16.2 18.1 0.036 13.8 2.8 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 C1_1 PF00130.17 CEP17436.1 - 0.011 15.3 0.3 0.011 15.3 0.2 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CENP-F_leu_zip PF10473.4 CEP17437.1 - 0.0027 17.5 3.9 0.0043 16.9 2.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 CEP17437.1 - 0.52 10.4 5.0 1.6 8.8 3.3 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family OrfB_Zn_ribbon PF07282.6 CEP17437.1 - 0.6 9.8 3.5 11 5.7 1.9 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain RRM_1 PF00076.17 CEP17440.1 - 8.8e-07 28.4 0.2 1.9e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17440.1 - 1.8e-05 24.5 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 CEP17440.1 - 0.0052 16.9 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.1 CEP17440.1 - 0.047 13.5 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosom_S12_S23 PF00164.20 CEP17441.1 - 2.8e-50 168.8 1.8 4.2e-50 168.2 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.22 CEP17442.1 - 6.8e-61 202.0 1.0 7.1e-24 83.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Brr6_like_C_C PF10104.4 CEP17443.1 - 2.7e-32 111.1 4.0 3.4e-32 110.8 2.7 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CYSTM PF12734.2 CEP17444.1 - 0.0086 16.1 0.7 0.0086 16.1 0.5 1.8 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance SURF2 PF05477.6 CEP17445.1 - 0.044 12.9 0.4 0.064 12.3 0.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2335 PF10097.4 CEP17445.1 - 0.095 12.3 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2335) Rab3-GTPase_cat PF13890.1 CEP17446.1 - 4.6e-51 172.4 0.5 1e-50 171.3 0.3 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Glycos_transf_2 PF00535.21 CEP17448.1 - 7.1e-32 110.4 0.0 8.7e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CEP17448.1 - 1.5e-12 47.8 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CEP17448.1 - 1.1e-09 37.8 0.0 1.5e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CEP17448.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF2834 PF11196.3 CEP17449.1 - 6.4e-06 26.2 1.5 6.4e-06 26.2 1.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2834) TraX PF05857.6 CEP17449.1 - 0.32 10.6 7.7 0.12 11.9 1.9 2.0 1 1 1 2 2 2 0 TraX protein SdpI PF13630.1 CEP17449.1 - 2.5 7.8 5.8 1.3 8.8 0.5 2.4 2 1 0 2 2 2 0 SdpI/YhfL protein family ABC2_membrane_2 PF12679.2 CEP17449.1 - 10 4.9 10.8 7.1 5.3 6.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein PP2C PF00481.16 CEP17450.1 - 1.6e-12 47.3 0.0 7.4e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 CEP17450.1 - 8e-07 28.6 0.0 1.3e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C YmaF PF12788.2 CEP17450.1 - 0.06 13.4 0.2 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 YmaF family C2 PF00168.25 CEP17452.1 - 0.00098 18.9 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain SDH_sah PF01972.11 CEP17452.1 - 0.042 12.6 0.3 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Serine dehydrogenase proteinase Bromodomain PF00439.20 CEP17453.1 - 4.8e-18 64.8 3.1 5.9e-18 64.5 0.7 2.2 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 CEP17453.1 - 5.1e-10 38.9 0.1 3e-09 36.4 0.0 2.2 1 1 1 2 2 2 1 Bromodomain associated PUF PF00806.14 CEP17454.1 - 5.2e-65 211.4 18.9 8.7e-09 34.3 0.1 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat tRNA_bind PF01588.15 CEP17455.1 - 3.3e-29 100.5 0.2 8.1e-29 99.3 0.0 1.8 2 0 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.1 CEP17455.1 - 5.8e-07 29.9 0.1 1.6e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP17455.1 - 0.0043 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEP17455.1 - 0.0066 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ras PF00071.17 CEP17456.1 - 1.9e-59 199.6 0.1 2.3e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP17456.1 - 9.5e-19 68.0 0.0 1.4e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP17456.1 - 1.6e-07 30.6 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP17456.1 - 0.0001 21.8 0.0 0.00016 21.1 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP17456.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3574 PF12098.3 CEP17457.1 - 0.042 13.4 0.6 0.95 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) Cofilin_ADF PF00241.15 CEP17458.1 - 2.8e-24 85.3 3.9 2e-12 47.0 1.1 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Cyclin PF08613.6 CEP17459.1 - 2.9e-37 128.3 1.4 3.9e-37 127.9 1.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP17459.1 - 0.00011 21.7 0.1 0.00018 21.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mating_C PF12737.2 CEP17459.1 - 0.00073 18.5 3.7 0.0012 17.8 2.5 1.2 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 DUF1212 PF06738.7 CEP17460.1 - 4.7e-21 75.1 26.9 5.4e-21 74.9 2.7 3.5 4 1 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CEP17460.1 - 1.7e-13 50.6 11.6 1.7e-13 50.6 8.1 2.9 3 1 0 3 3 3 2 Protein of unknown function (DUF3815) DUF4526 PF15029.1 CEP17460.1 - 0.0052 16.3 0.1 0.073 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4526) DEAD PF00270.24 CEP17461.1 - 1.8e-35 121.9 1.2 2.6e-33 114.8 0.1 3.2 2 2 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP17461.1 - 9.8e-28 95.8 0.0 2.1e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 CEP17461.1 - 5.9 6.0 8.0 49 3.0 0.0 3.7 5 0 0 5 5 5 0 SecA DEAD-like domain Sod_Cu PF00080.15 CEP17463.1 - 4.9e-45 153.1 2.9 5.8e-45 152.9 2.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ank_2 PF12796.2 CEP17466.1 - 4.1e-27 94.3 6.1 2.1e-08 34.3 0.6 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEP17466.1 - 1.6e-26 92.1 5.0 1.8e-10 41.0 0.4 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP17466.1 - 3.1e-23 81.2 5.7 1e-08 35.1 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP17466.1 - 1.3e-21 74.5 8.1 0.00059 19.8 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.25 CEP17466.1 - 1.1e-20 72.3 12.6 1.9e-06 27.3 0.0 5.7 5 1 1 6 6 6 5 Ankyrin repeat FYVE PF01363.16 CEP17466.1 - 1.8e-17 63.0 7.4 1.8e-17 63.0 5.1 2.3 2 0 0 2 2 2 1 FYVE zinc finger Trm112p PF03966.11 CEP17466.1 - 0.0076 16.5 0.2 0.034 14.5 0.0 2.2 2 0 0 2 2 2 1 Trm112p-like protein DUF2039 PF10217.4 CEP17466.1 - 0.045 13.7 7.1 0.14 12.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) HypA PF01155.14 CEP17466.1 - 0.17 11.5 6.9 0.034 13.8 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 CEP17466.1 - 0.41 10.5 12.0 0.23 11.3 6.1 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger RNA_pol_Rpb1_1 PF04997.7 CEP17467.1 - 1.3e-122 409.2 0.2 3.6e-122 407.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CEP17467.1 - 1e-106 356.2 0.5 1e-106 356.2 0.4 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 CEP17467.1 - 4.8e-71 238.3 0.7 4.8e-71 238.3 0.5 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.15 CEP17467.1 - 1.5e-70 236.4 0.0 4.6e-70 234.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CEP17467.1 - 6.5e-52 175.4 0.0 2.3e-51 173.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CEP17467.1 - 5.2e-47 158.9 5.5 5.2e-47 158.9 3.8 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CEP17467.1 - 3.2e-39 132.9 0.7 8.8e-39 131.5 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CEP17467.1 - 3.7e-15 54.6 340.3 0.033 14.2 8.6 17.5 5 2 16 25 25 25 23 RNA polymerase Rpb1 C-terminal repeat DUF3090 PF11290.3 CEP17467.1 - 0.017 14.6 0.4 0.054 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) p450 PF00067.17 CEP17468.1 - 2.3e-36 125.3 0.0 8.7e-36 123.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF4602 PF15375.1 CEP17469.1 - 5.3 7.1 22.1 0.02 14.9 7.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) FA_FANCE PF11510.3 CEP17470.1 - 5.5e-07 28.9 4.8 1.4e-06 27.6 0.7 2.4 1 1 1 2 2 2 2 Fanconi Anaemia group E protein FANCE BID PF06393.6 CEP17470.1 - 0.021 14.1 0.2 0.035 13.4 0.2 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) MFS_1 PF07690.11 CEP17471.1 - 2.5e-26 92.2 31.3 3.5e-26 91.7 21.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NCU-G1 PF15065.1 CEP17472.1 - 1.3e-08 33.8 4.6 2.4e-08 33.0 3.2 1.3 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 Vps8 PF12816.2 CEP17473.1 - 1.5e-65 220.1 0.0 1.5e-62 210.3 0.0 2.8 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 CEP17473.1 - 4.7e-07 29.4 3.4 0.012 15.2 0.0 3.8 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 CEP17473.1 - 0.00059 19.6 1.9 0.0014 18.3 1.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEP17473.1 - 0.00098 18.8 1.9 0.0022 17.6 1.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEP17473.1 - 0.0023 17.5 1.6 0.0068 16.0 1.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP17473.1 - 0.0024 17.8 2.2 0.0024 17.8 1.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEP17473.1 - 0.0028 17.7 1.0 0.0072 16.4 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP17473.1 - 0.3 10.7 2.6 0.28 10.8 0.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ACOX PF01756.14 CEP17474.1 - 1.1e-51 174.8 0.0 2e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEP17474.1 - 3.5e-15 56.4 0.1 8.1e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEP17474.1 - 7.4e-15 54.2 1.1 2.8e-14 52.3 0.4 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEP17474.1 - 1.1e-07 32.0 0.6 1.1e-06 28.8 0.4 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Vps53_N PF04100.7 CEP17475.1 - 7.7e-99 331.0 9.9 7.7e-99 331.0 6.9 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF237 PF03072.9 CEP17475.1 - 0.05 13.5 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 MG032/MG096/MG288 family 1 COG2 PF06148.6 CEP17475.1 - 1.8 8.4 10.3 43 3.9 4.3 4.0 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_integrase PF00589.17 CEP17476.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Phage integrase family PAS_2 PF08446.6 CEP17477.1 - 0.037 14.4 1.7 0.09 13.2 0.1 2.5 3 0 0 3 3 3 0 PAS fold SDA1 PF05285.7 CEP17478.1 - 4.1e-80 269.4 40.6 5.7e-80 269.0 21.3 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 CEP17478.1 - 1.5e-21 76.3 0.3 1.5e-21 76.3 0.2 2.3 2 0 0 2 2 2 1 NUC130/3NT domain Mating_N PF12731.2 CEP17478.1 - 0.02 14.7 0.1 0.066 13.1 0.1 1.9 1 0 0 1 1 1 0 Mating-type protein beta 1 Porin_3 PF01459.17 CEP17479.1 - 1e-61 208.6 8.5 1.2e-61 208.4 5.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4115 PF13464.1 CEP17479.1 - 0.057 13.0 0.0 18 5.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4115) TGT PF01702.13 CEP17480.1 - 1.4e-91 305.9 0.0 1.8e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF2346 PF09803.4 CEP17481.1 - 0.006 16.4 0.7 0.035 13.9 0.5 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Ribonuc_2-5A PF06479.7 CEP17481.1 - 0.078 12.8 0.3 0.091 12.6 0.2 1.1 1 0 0 1 1 1 0 Ribonuclease 2-5A Pro_isomerase PF00160.16 CEP17482.1 - 2.8e-46 157.5 0.1 2.8e-46 157.5 0.1 1.9 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U79_P34 PF03064.11 CEP17482.1 - 0.49 9.8 21.4 0.79 9.1 14.8 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Raftlin PF15250.1 CEP17482.1 - 0.8 8.1 13.1 1.2 7.6 9.0 1.1 1 0 0 1 1 1 0 Raftlin Mem_trans PF03547.13 CEP17482.1 - 0.9 7.7 5.9 1.3 7.2 4.1 1.3 1 0 0 1 1 1 0 Membrane transport protein LMBR1 PF04791.11 CEP17482.1 - 3 6.3 10.0 3.7 6.0 6.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4661 PF15576.1 CEP17482.1 - 5.9 6.4 15.0 8.7 5.9 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) UPRTase PF14681.1 CEP17483.1 - 1.1e-65 220.7 0.0 1.6e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 CEP17483.1 - 4.2e-61 205.9 0.1 7.5e-61 205.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CEP17483.1 - 1.6e-07 31.6 0.0 3.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP17483.1 - 5.1e-06 27.2 0.1 1.6e-05 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 CEP17483.1 - 1.1e-05 25.1 0.0 2.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 CEP17483.1 - 0.00017 21.4 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 CEP17483.1 - 0.0018 17.6 0.4 0.03 13.7 0.2 2.2 1 1 0 1 1 1 1 Dephospho-CoA kinase DUF4257 PF14074.1 CEP17483.1 - 0.007 15.9 0.3 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4257) Zeta_toxin PF06414.7 CEP17483.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RRM_1 PF00076.17 CEP17485.1 - 8.3e-32 108.6 0.2 1.7e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17485.1 - 8.8e-22 76.8 0.1 2.5e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP17485.1 - 5.5e-10 38.9 0.0 2.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP17485.1 - 1.5e-06 27.9 0.8 0.0054 16.5 0.0 2.3 1 1 1 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 CEP17485.1 - 1.4e-05 24.7 1.9 0.067 12.9 0.2 2.6 1 1 1 2 2 2 2 Limkain b1 DUF566 PF04484.7 CEP17485.1 - 4.4 6.7 22.4 6.1 6.2 15.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) MatE PF01554.13 CEP17486.1 - 1.8e-42 144.7 39.5 1.3e-24 86.7 8.1 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 CEP17486.1 - 0.0014 18.4 10.2 0.0014 18.4 7.1 4.2 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MOZ_SAS PF01853.13 CEP17487.1 - 7.4e-88 292.7 1.3 7.4e-88 292.7 0.9 1.8 2 0 0 2 2 2 1 MOZ/SAS family PHD PF00628.24 CEP17487.1 - 2e-12 46.5 29.7 7.6e-11 41.5 8.3 3.5 2 1 1 3 3 3 2 PHD-finger AT_hook PF02178.14 CEP17487.1 - 0.39 10.5 4.7 1 9.2 3.2 1.8 1 0 0 1 1 1 0 AT hook motif zf-C2H2_jaz PF12171.3 CEP17487.1 - 3 8.0 10.0 1.8 8.7 0.5 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FAD_binding_6 PF00970.19 CEP17488.1 - 9.3e-30 102.6 0.0 1.4e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CEP17488.1 - 6.2e-26 91.0 0.0 9e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CEP17488.1 - 1.1e-07 31.9 0.0 1.4e-06 28.2 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CEP17488.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Sugar_tr PF00083.19 CEP17489.1 - 2.7e-43 148.1 24.7 4.1e-26 91.5 5.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP17489.1 - 5e-19 68.2 37.4 5.7e-10 38.4 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_11 PF13414.1 CEP17490.1 - 5.4e-20 70.8 3.5 1e-07 31.4 0.1 3.8 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CEP17490.1 - 2.9e-16 58.2 1.8 3.6e-05 23.1 0.0 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CEP17490.1 - 9.7e-10 37.6 2.8 0.00023 20.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP17490.1 - 3.8e-08 33.1 5.8 0.001 18.9 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP17490.1 - 7.9e-08 32.2 7.1 0.051 14.2 0.1 4.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP17490.1 - 2.4e-07 31.2 4.4 0.021 15.4 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEP17490.1 - 3.7e-07 30.3 3.1 0.0052 17.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 CEP17490.1 - 8.6e-07 28.9 3.8 0.0045 17.0 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP17490.1 - 4.8e-06 26.3 1.9 0.00059 19.8 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP17490.1 - 0.00013 21.5 0.5 0.011 15.4 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP17490.1 - 0.00072 19.4 0.4 0.029 14.2 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CEP17490.1 - 0.00078 19.2 4.8 0.035 13.9 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP17490.1 - 0.0011 18.6 0.2 3.9 7.5 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP17490.1 - 0.0085 16.4 1.0 0.72 10.4 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat SnAC PF14619.1 CEP17490.1 - 0.032 14.4 1.2 0.11 12.7 0.9 1.9 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex HD_3 PF13023.1 CEP17491.1 - 2.3e-44 151.0 0.3 2.6e-44 150.8 0.2 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.17 CEP17491.1 - 8.3e-06 25.8 0.1 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 HD domain MMR_HSR1 PF01926.18 CEP17492.1 - 1.7e-14 53.7 0.0 3.5e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP17492.1 - 3.4e-05 23.1 0.1 0.00076 18.7 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 CEP17492.1 - 4.3e-05 22.7 0.0 8.8e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CEP17492.1 - 0.00094 19.0 0.4 0.0077 16.0 0.1 2.4 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 CEP17492.1 - 0.003 17.0 0.0 0.38 10.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CEP17492.1 - 0.0042 16.2 0.0 0.011 14.7 0.0 1.7 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.4 CEP17492.1 - 0.005 16.3 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CEP17492.1 - 0.0053 17.2 0.1 0.041 14.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 CEP17492.1 - 0.049 13.3 0.1 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ASCH PF04266.9 CEP17492.1 - 0.13 12.6 1.2 0.37 11.2 0.8 1.7 1 0 0 1 1 1 0 ASCH domain ABC_tran PF00005.22 CEP17492.1 - 0.14 12.4 0.0 1.6 9.0 0.0 2.4 2 1 0 2 2 2 0 ABC transporter GAT PF03127.9 CEP17493.1 - 6.8e-09 35.6 0.3 1.9e-08 34.1 0.2 1.8 1 1 0 1 1 1 1 GAT domain VHS PF00790.14 CEP17493.1 - 2e-08 33.9 0.0 0.0016 18.0 0.0 2.6 1 1 1 2 2 2 2 VHS domain Mito_fiss_reg PF05308.6 CEP17493.1 - 0.025 13.9 0.2 0.025 13.9 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator PB1 PF00564.19 CEP17493.1 - 0.11 12.1 0.2 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 PB1 domain RhoGAP PF00620.22 CEP17494.1 - 6.2e-38 129.7 0.0 1.1e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain QCR10 PF09796.4 CEP17494.1 - 1.3e-15 56.8 0.0 2.4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_hydro_16 PF00722.16 CEP17495.1 - 2.1e-28 98.8 0.9 2.9e-28 98.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1461 PF07314.6 CEP17496.1 - 0.15 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Thioredoxin PF00085.15 CEP17497.1 - 9.1e-56 185.9 0.3 5.2e-27 93.5 0.1 4.3 4 0 0 4 4 4 2 Thioredoxin Ribonuc_P_40 PF08584.6 CEP17497.1 - 7.6e-50 169.5 0.3 1.1e-49 168.9 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Thioredoxin_6 PF13848.1 CEP17497.1 - 7.8e-33 113.8 0.6 2.6e-23 82.7 0.1 3.6 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CEP17497.1 - 7.4e-13 48.6 0.8 0.0061 16.7 0.1 5.4 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEP17497.1 - 1.2e-09 38.1 0.8 0.015 15.4 0.0 5.1 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CEP17497.1 - 3.7e-09 36.4 0.2 0.0027 17.6 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 CEP17497.1 - 7.2e-06 25.6 1.1 1 8.8 0.0 3.4 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 CEP17497.1 - 1e-05 25.1 0.5 0.28 10.8 0.0 3.2 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 CEP17497.1 - 0.0018 18.1 0.0 0.29 11.0 0.0 2.7 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 CEP17497.1 - 0.056 13.2 0.2 0.39 10.5 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain BTG PF07742.7 CEP17498.1 - 2.4e-30 104.4 0.0 3.7e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 BTG family APG6 PF04111.7 CEP17499.1 - 0.03 13.3 6.8 0.052 12.5 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Lebercilin PF15619.1 CEP17499.1 - 0.031 13.6 8.3 0.97 8.8 5.4 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Dus PF01207.12 CEP17499.1 - 0.097 11.4 1.9 0.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) XhlA PF10779.4 CEP17499.1 - 0.12 12.2 1.1 0.37 10.7 0.8 1.9 1 0 0 1 1 1 0 Haemolysin XhlA IncA PF04156.9 CEP17499.1 - 0.91 9.0 4.2 1.8 8.1 2.9 1.4 1 0 0 1 1 1 0 IncA protein DUF3169 PF11368.3 CEP17500.1 - 0.18 10.9 0.1 0.18 10.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) NADH-u_ox-rdase PF10785.4 CEP17500.1 - 0.37 11.0 3.2 5.1 7.4 0.4 3.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF962 PF06127.6 CEP17500.1 - 0.4 10.6 8.6 0.27 11.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF962) Methyltransf_23 PF13489.1 CEP17501.1 - 2.4e-14 53.3 0.0 4.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP17501.1 - 1.2e-11 44.9 0.0 3.8e-11 43.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP17501.1 - 4.9e-11 43.2 0.0 2.1e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP17501.1 - 2.3e-10 40.8 0.0 1.4e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP17501.1 - 1.1e-08 34.8 0.0 5e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP17501.1 - 2.4e-08 33.3 0.0 4.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEP17501.1 - 3.8e-08 33.5 0.0 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP17501.1 - 7e-05 22.2 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 CEP17501.1 - 8.7e-05 21.6 0.0 0.00095 18.2 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 CEP17501.1 - 0.00019 21.4 0.0 0.00044 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CEP17501.1 - 0.00076 18.8 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 CEP17501.1 - 0.0021 17.3 0.1 0.016 14.5 0.0 2.3 3 0 0 3 3 3 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 CEP17501.1 - 0.0034 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.9 CEP17501.1 - 0.015 14.5 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 CEP17501.1 - 0.023 15.5 0.0 0.06 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CEP17501.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SMN PF06003.7 CEP17502.1 - 2.3e-06 26.9 3.0 3.1e-06 26.4 2.1 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF1325 PF07039.6 CEP17502.1 - 0.00019 21.0 0.1 0.00056 19.5 0.1 1.9 1 1 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 CEP17502.1 - 0.00035 20.3 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.5 CEP17502.1 - 0.0036 16.8 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain IER PF05760.7 CEP17502.1 - 0.069 13.0 3.4 0.086 12.7 2.4 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) TUDOR PF00567.19 CEP17502.1 - 0.095 12.5 0.1 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 Tudor domain SR-25 PF10500.4 CEP17502.1 - 0.14 11.5 5.3 0.26 10.7 3.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sds3 PF08598.6 CEP17503.1 - 4.4e-17 62.3 18.5 7.8e-17 61.4 12.8 1.4 1 0 0 1 1 1 1 Sds3-like zf-met PF12874.2 CEP17504.1 - 2e-06 27.8 62.2 0.0038 17.3 1.2 9.6 10 0 0 10 10 10 6 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CEP17504.1 - 0.00065 19.8 87.5 0.48 10.8 1.5 10.6 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CEP17504.1 - 0.01 15.9 73.3 0.03 14.4 1.6 9.1 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding Ribosomal_L31 PF01197.13 CEP17504.1 - 0.079 12.9 5.7 8.6 6.4 0.0 5.4 6 0 0 6 6 6 0 Ribosomal protein L31 Zn-ribbon_8 PF09723.5 CEP17504.1 - 0.15 12.0 0.1 0.15 12.0 0.0 7.3 9 0 0 9 9 9 0 Zinc ribbon domain GBP_repeat PF02526.9 CEP17504.1 - 0.38 10.1 9.4 1.7 8.0 0.1 4.3 4 0 0 4 4 4 0 Glycophorin-binding protein zf-C2H2_4 PF13894.1 CEP17504.1 - 0.8 10.1 81.9 0.31 11.4 2.8 10.2 10 0 0 10 10 10 0 C2H2-type zinc finger DUF2757 PF10955.3 CEP17504.1 - 1.6 9.0 0.0 1.6 9.0 0.0 5.5 7 0 0 7 7 7 0 Protein of unknown function (DUF2757) Glyco_hydro_16 PF00722.16 CEP17505.1 - 4.9e-21 74.8 0.1 8.4e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pro_isomerase PF00160.16 CEP17507.1 - 2e-48 164.5 0.1 2.3e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1403 PF07183.6 CEP17508.1 - 0.027 13.8 0.6 0.046 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) Retrotrans_gag PF03732.12 CEP17509.1 - 1.2e-06 28.5 3.3 5.2e-06 26.4 0.1 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein Phage_int_SAM_4 PF13495.1 CEP17510.1 - 0.03 14.6 4.9 2.1 8.7 0.0 3.0 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain APC2 PF08672.6 CEP17510.1 - 0.068 13.4 0.1 3.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Spore_GerAC PF05504.6 CEP17510.1 - 0.072 12.8 0.6 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Phytoreo_S7 PF07236.6 CEP17511.1 - 0.0071 14.7 0.3 0.012 14.0 0.2 1.3 1 0 0 1 1 1 1 Phytoreovirus S7 protein Atg14 PF10186.4 CEP17513.1 - 9.7e-05 21.4 9.1 0.00011 21.2 6.3 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CAF-1_p150 PF11600.3 CEP17513.1 - 0.022 14.1 18.3 0.028 13.8 12.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SpoVR PF04293.8 CEP17513.1 - 0.023 13.1 7.0 0.025 12.9 4.9 1.0 1 0 0 1 1 1 0 SpoVR like protein SSP160 PF06933.6 CEP17513.1 - 0.1 10.5 2.9 0.11 10.4 2.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RNase_H2-Ydr279 PF09468.5 CEP17513.1 - 0.13 11.4 9.5 0.14 11.3 6.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3584 PF12128.3 CEP17513.1 - 0.2 8.9 15.0 0.21 8.8 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Dicty_REP PF05086.7 CEP17513.1 - 0.42 8.3 14.4 0.49 8.0 10.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA_13 PF13166.1 CEP17513.1 - 0.49 8.7 15.1 0.6 8.5 10.5 1.0 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 CEP17513.1 - 0.59 9.6 16.5 0.052 13.0 1.4 2.3 2 0 0 2 2 2 0 Septum formation initiator HrpB7 PF09486.5 CEP17513.1 - 0.7 9.7 5.1 5.4 6.9 0.3 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GAGA_bind PF06217.7 CEP17513.1 - 1 9.2 13.7 1.2 8.9 9.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family TMF_DNA_bd PF12329.3 CEP17513.1 - 1.4 8.7 18.2 0.26 11.1 3.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Choline_kinase PF01633.15 CEP17513.1 - 1.4 8.4 5.7 3.5 7.1 3.9 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase RP-C_C PF11800.3 CEP17513.1 - 2.3 7.8 11.3 3 7.4 7.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region CDC37_N PF03234.9 CEP17513.1 - 2.5 8.3 13.5 3.9 7.7 9.4 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4407 PF14362.1 CEP17513.1 - 2.6 6.9 14.6 3.4 6.5 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.12 CEP17513.1 - 2.7 7.7 10.9 3.3 7.4 7.6 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_S46 PF10459.4 CEP17513.1 - 3.1 6.0 12.2 3.5 5.9 8.5 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF342 PF03961.8 CEP17513.1 - 3.7 5.8 9.1 4.9 5.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FLO_LFY PF01698.11 CEP17513.1 - 3.7 6.2 10.1 4.2 6.1 7.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein AUX_IAA PF02309.11 CEP17513.1 - 4.7 6.8 11.2 5.7 6.6 7.8 1.2 1 0 0 1 1 1 0 AUX/IAA family RR_TM4-6 PF06459.7 CEP17513.1 - 6.3 6.5 12.6 7.8 6.3 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3450 PF11932.3 CEP17513.1 - 6.5 5.9 21.4 0.053 12.7 1.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1675 PF07897.6 CEP17513.1 - 9.4 6.0 12.0 12 5.6 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Cg6151-P PF10233.4 CEP17515.1 - 2.1e-07 30.8 12.5 1.5e-05 24.9 8.5 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4149 PF13664.1 CEP17515.1 - 0.041 13.9 4.1 0.15 12.1 2.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) DUF2651 PF10852.3 CEP17515.1 - 1.5 9.2 8.5 0.81 10.0 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) Tenui_PVC2 PF06656.6 CEP17515.1 - 3.7 5.2 7.9 0.093 10.5 1.1 1.4 2 0 0 2 2 2 0 Tenuivirus PVC2 protein DUF1430 PF07242.6 CEP17515.1 - 4.3 7.4 10.8 3.2 7.8 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) SdpI PF13630.1 CEP17515.1 - 4.3 7.1 14.5 1.7 8.3 3.9 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family Myb_DNA-binding PF00249.26 CEP17516.1 - 1.4e-19 69.8 0.5 2.7e-08 33.7 0.1 4.0 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP17516.1 - 9.8e-09 35.1 9.2 5.2e-05 23.2 0.5 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Pkinase PF00069.20 CEP17517.1 - 5.7e-70 235.4 0.0 7.8e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17517.1 - 5.5e-32 110.8 0.1 4.1e-31 107.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP17517.1 - 5.7e-08 32.0 0.4 0.019 13.9 0.0 3.1 2 1 1 3 3 3 3 Kinase-like APH PF01636.18 CEP17517.1 - 0.0023 17.6 0.0 1.1 8.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEP17517.1 - 0.092 11.8 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tropomyosin_1 PF12718.2 CEP17518.1 - 1.1e-14 54.5 23.5 1.8e-13 50.5 16.3 1.9 1 1 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CEP17518.1 - 1.3e-08 34.2 23.7 1.9e-08 33.6 16.4 1.3 1 0 0 1 1 1 1 Tropomyosin AAA_13 PF13166.1 CEP17518.1 - 3.9e-05 22.3 17.5 4.4e-05 22.1 12.1 1.0 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 CEP17518.1 - 0.0003 20.3 16.3 0.00039 19.9 11.3 1.3 1 0 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.3 CEP17518.1 - 0.00038 20.2 28.9 0.058 13.2 7.8 2.2 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 CEP17518.1 - 0.00052 19.8 2.7 0.00065 19.5 1.6 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CEP17518.1 - 0.00057 19.5 15.5 0.00057 19.5 10.7 1.9 1 1 1 2 2 2 1 IncA protein Laminin_II PF06009.7 CEP17518.1 - 0.0009 19.0 6.3 0.0009 19.0 4.3 2.2 1 1 1 2 2 2 1 Laminin Domain II NPV_P10 PF05531.7 CEP17518.1 - 0.0012 19.0 2.6 0.0012 19.0 1.8 2.5 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein FH2 PF02181.18 CEP17518.1 - 0.0018 17.2 6.9 0.0018 17.2 4.8 2.0 1 1 1 2 2 2 1 Formin Homology 2 Domain DUF1943 PF09172.6 CEP17518.1 - 0.0028 16.5 3.3 0.0034 16.2 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) DUF745 PF05335.8 CEP17518.1 - 0.005 16.3 4.7 0.005 16.3 3.2 1.8 1 1 0 2 2 2 1 Protein of unknown function (DUF745) DUF3584 PF12128.3 CEP17518.1 - 0.0057 14.0 17.5 0.0065 13.8 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 CEP17518.1 - 0.0071 14.1 23.9 0.0093 13.7 16.6 1.2 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 CEP17518.1 - 0.0075 16.1 22.7 0.19 11.5 8.1 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.1 CEP17518.1 - 0.0077 15.4 24.7 0.068 12.3 17.1 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 CEP17518.1 - 0.015 14.0 22.0 0.078 11.6 15.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein TarH PF02203.10 CEP17518.1 - 0.019 14.7 2.1 0.019 14.7 1.5 1.5 2 0 0 2 2 1 0 Tar ligand binding domain homologue DUF812 PF05667.6 CEP17518.1 - 0.023 13.2 18.3 0.051 12.0 12.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ERM PF00769.14 CEP17518.1 - 0.024 14.1 22.4 0.053 13.0 15.5 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 CEP17518.1 - 0.025 13.7 1.2 0.037 13.2 0.7 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein SH3BP5 PF05276.9 CEP17518.1 - 0.026 13.8 11.6 0.036 13.3 8.1 1.3 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) EzrA PF06160.7 CEP17518.1 - 0.028 12.6 18.7 0.03 12.5 10.8 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA CALCOCO1 PF07888.6 CEP17518.1 - 0.033 12.4 14.9 0.017 13.4 5.5 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TBPIP PF07106.8 CEP17518.1 - 0.033 13.7 22.9 0.7 9.4 8.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 CEP17518.1 - 0.035 13.9 25.7 0.026 14.3 10.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 CEP17518.1 - 0.037 13.9 20.8 0.47 10.3 13.4 2.3 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2009 PF09418.5 CEP17518.1 - 0.038 12.7 2.8 0.036 12.8 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) APG6 PF04111.7 CEP17518.1 - 0.038 13.0 23.0 0.052 12.5 15.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Sugarporin_N PF11471.3 CEP17518.1 - 0.039 13.5 0.1 0.039 13.5 0.1 2.7 3 0 0 3 3 2 0 Maltoporin periplasmic N-terminal extension AAA_27 PF13514.1 CEP17518.1 - 0.041 11.5 13.8 0.058 11.0 9.5 1.3 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 CEP17518.1 - 0.054 13.6 13.2 0.19 11.8 5.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NDT80_PhoG PF05224.7 CEP17518.1 - 0.062 13.2 3.2 0.071 13.1 2.2 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family WXG100 PF06013.7 CEP17518.1 - 0.067 13.2 8.4 14 5.7 0.2 3.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG TMF_TATA_bd PF12325.3 CEP17518.1 - 0.07 12.8 22.8 0.26 11.0 15.4 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DASH_Duo1 PF08651.5 CEP17518.1 - 0.074 12.6 0.2 0.074 12.6 0.1 2.6 2 1 1 3 3 2 0 DASH complex subunit Duo1 V-SNARE PF05008.10 CEP17518.1 - 0.075 13.1 19.6 0.023 14.8 8.1 2.4 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus BLOC1_2 PF10046.4 CEP17518.1 - 0.078 13.1 17.7 0.13 12.4 6.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FTO_CTD PF12934.2 CEP17518.1 - 0.085 12.4 5.5 0.023 14.2 1.4 1.7 1 1 1 2 2 2 0 FTO C-terminal domain TPR_MLP1_2 PF07926.7 CEP17518.1 - 0.1 12.3 23.2 0.79 9.4 9.8 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 CEP17518.1 - 0.11 12.3 13.2 0.051 13.3 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vac_Fusion PF02346.11 CEP17518.1 - 0.15 11.4 10.9 2.2 7.7 0.4 3.1 2 1 1 3 3 3 0 Chordopoxvirus fusion protein Angiomotin_C PF12240.3 CEP17518.1 - 0.16 11.4 12.3 0.66 9.4 1.9 2.0 1 1 1 2 2 2 0 Angiomotin C terminal MCPsignal PF00015.16 CEP17518.1 - 0.17 11.4 3.1 0.13 11.7 0.6 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF489 PF04356.7 CEP17518.1 - 0.23 11.0 5.2 0.75 9.3 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Bacillus_HBL PF05791.6 CEP17518.1 - 0.25 10.7 16.8 0.053 12.8 4.9 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMCO5 PF14992.1 CEP17518.1 - 0.25 10.4 21.1 0.39 9.8 14.7 1.3 1 1 0 1 1 1 0 TMCO5 family Syntaxin-6_N PF09177.6 CEP17518.1 - 0.29 11.5 14.2 0.96 9.8 5.6 2.9 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4315 PF14193.1 CEP17518.1 - 0.29 11.0 21.9 0.073 13.0 7.7 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4315) LOH1CR12 PF10158.4 CEP17518.1 - 0.31 10.8 4.0 0.53 10.0 2.5 1.8 1 1 1 2 2 2 0 Tumour suppressor protein DUF4200 PF13863.1 CEP17518.1 - 0.33 10.9 26.3 0.37 10.7 9.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HOOK PF05622.7 CEP17518.1 - 0.37 8.5 18.7 0.45 8.2 13.0 1.1 1 0 0 1 1 1 0 HOOK protein FliD_C PF07195.7 CEP17518.1 - 0.41 9.9 9.7 1.4 8.1 6.7 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus IFT57 PF10498.4 CEP17518.1 - 0.43 9.2 17.5 0.1 11.3 6.3 1.8 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 YkyA PF10368.4 CEP17518.1 - 0.46 9.7 19.8 2.9 7.1 13.8 1.9 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Peptidase_M27 PF01742.12 CEP17518.1 - 0.47 9.2 5.4 0.48 9.2 3.7 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease Fez1 PF06818.10 CEP17518.1 - 0.61 10.0 14.9 0.12 12.3 7.3 1.7 1 1 1 2 2 2 0 Fez1 WEMBL PF05701.6 CEP17518.1 - 0.64 8.4 21.1 29 2.9 1.7 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF641 PF04859.7 CEP17518.1 - 0.64 9.7 15.2 2.1 8.0 4.3 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF948 PF06103.6 CEP17518.1 - 0.64 9.9 10.3 0.16 11.8 3.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Vps5 PF09325.5 CEP17518.1 - 0.65 9.2 15.0 0.03 13.5 5.5 2.0 1 1 1 2 2 2 0 Vps5 C terminal like CENP-Q PF13094.1 CEP17518.1 - 0.65 10.0 28.3 3.2 7.7 10.8 2.9 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4559 PF15112.1 CEP17518.1 - 0.69 9.0 13.3 0.87 8.6 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TMPIT PF07851.8 CEP17518.1 - 0.72 8.8 11.7 0.88 8.5 8.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cytochrom_C_2 PF01322.15 CEP17518.1 - 0.75 10.3 4.9 11 6.5 0.4 2.2 2 0 0 2 2 2 0 Cytochrome C' DUF4363 PF14276.1 CEP17518.1 - 0.76 9.4 11.0 0.088 12.5 3.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) Prefoldin_2 PF01920.15 CEP17518.1 - 0.77 9.5 28.6 2 8.1 0.6 3.2 1 1 2 3 3 3 0 Prefoldin subunit COG2 PF06148.6 CEP17518.1 - 0.78 9.6 11.6 0.19 11.6 4.2 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MAD PF05557.8 CEP17518.1 - 0.81 7.6 21.3 1 7.3 14.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein PspA_IM30 PF04012.7 CEP17518.1 - 0.85 8.9 19.4 0.49 9.7 6.3 2.8 1 1 1 2 2 2 0 PspA/IM30 family Pox_F11 PF04943.7 CEP17518.1 - 0.89 8.3 6.0 0.93 8.2 4.2 1.0 1 0 0 1 1 1 0 Poxvirus F11 protein Nup54 PF13874.1 CEP17518.1 - 0.91 9.1 14.4 2.4 7.8 1.5 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Med9 PF07544.8 CEP17518.1 - 0.94 9.2 16.2 6 6.6 9.7 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.3 CEP17518.1 - 1 8.5 14.1 1.2 8.3 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prominin PF05478.6 CEP17518.1 - 1 6.7 9.6 1.2 6.5 6.7 1.0 1 0 0 1 1 1 0 Prominin DUF3552 PF12072.3 CEP17518.1 - 1.1 8.4 22.4 2.9 7.0 15.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Zw10 PF06248.8 CEP17518.1 - 1.1 7.3 12.0 1.2 7.1 8.3 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 FliJ PF02050.11 CEP17518.1 - 1.1 9.2 17.8 5 7.1 12.3 2.1 1 1 0 1 1 1 0 Flagellar FliJ protein DUF724 PF05266.9 CEP17518.1 - 1.2 8.7 20.8 46 3.5 14.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF2730 PF10805.3 CEP17518.1 - 1.3 8.8 11.5 1.7 8.4 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FliD_N PF02465.13 CEP17518.1 - 1.3 9.4 7.3 1.7 9.0 2.9 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF2408 PF10303.4 CEP17518.1 - 1.4 9.0 13.8 2.1 8.4 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Allexi_40kDa PF05549.6 CEP17518.1 - 1.5 8.0 13.2 0.64 9.2 2.1 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Atg14 PF10186.4 CEP17518.1 - 1.6 7.6 17.8 1.9 7.3 12.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 CEP17518.1 - 1.7 8.9 18.3 0.96 9.7 6.5 2.6 1 1 1 2 2 2 0 Spectrin repeat Mnd1 PF03962.10 CEP17518.1 - 2 8.0 21.0 1e+02 2.4 14.6 2.1 1 1 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 CEP17518.1 - 2.1 6.6 20.7 0.24 9.7 8.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) HalX PF08663.5 CEP17518.1 - 2.1 8.3 13.9 0.84 9.6 3.1 3.1 1 1 0 3 3 3 0 HalX domain V_ATPase_I PF01496.14 CEP17518.1 - 2.2 6.0 17.9 6.9 4.3 12.4 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family UvrD-helicase PF00580.16 CEP17518.1 - 2.3 7.4 12.2 2.3 7.4 8.5 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Cep57_CLD PF14073.1 CEP17518.1 - 2.3 8.0 23.6 0.96 9.2 9.0 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF3810 PF12725.2 CEP17518.1 - 2.4 6.9 6.6 1.2 7.9 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4201 PF13870.1 CEP17518.1 - 2.6 7.4 23.6 0.66 9.3 8.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF603 PF04645.7 CEP17518.1 - 2.7 7.8 15.1 4.1 7.2 3.2 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF603 Seryl_tRNA_N PF02403.17 CEP17518.1 - 2.8 8.0 22.4 5.9 6.9 6.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 CEP17518.1 - 3 7.8 16.4 11 5.9 5.3 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) SlyX PF04102.7 CEP17518.1 - 3 8.2 13.8 2.4 8.6 2.5 2.7 1 1 2 3 3 2 0 SlyX Noelin-1 PF12308.3 CEP17518.1 - 3.1 7.6 5.8 2.9 7.7 2.2 2.0 1 1 1 2 2 2 0 Neurogenesis glycoprotein Med3 PF11593.3 CEP17518.1 - 3.3 6.8 6.3 4.8 6.3 4.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Striatin PF08232.7 CEP17518.1 - 3.7 7.8 16.4 12 6.1 11.4 1.9 1 1 0 1 1 1 0 Striatin family Prefoldin PF02996.12 CEP17518.1 - 3.8 7.1 22.0 3.8 7.1 1.9 3.3 1 1 2 3 3 3 0 Prefoldin subunit Occludin_ELL PF07303.8 CEP17518.1 - 4 8.2 15.3 1.8 9.3 4.9 3.0 1 1 1 2 2 2 0 Occludin homology domain Phage_GP20 PF06810.6 CEP17518.1 - 4.1 6.8 27.1 0.85 9.0 6.1 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 HSP70 PF00012.15 CEP17518.1 - 4.2 5.1 16.9 4.4 5.0 11.7 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2203 PF09969.4 CEP17518.1 - 4.7 7.4 11.8 1.3 9.2 2.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Hrs_helical PF12210.3 CEP17518.1 - 5.3 7.3 11.1 9.8 6.5 1.9 2.4 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Adeno_PIX PF03955.9 CEP17518.1 - 5.6 7.5 6.3 13 6.3 0.8 2.2 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Rootletin PF15035.1 CEP17518.1 - 5.9 6.8 18.1 1e+02 2.7 12.6 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fmp27_WPPW PF10359.4 CEP17518.1 - 6 5.1 18.9 0.36 9.1 4.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Ribonuc_2-5A PF06479.7 CEP17518.1 - 6.1 6.7 7.9 12 5.8 5.5 1.5 1 1 0 1 1 1 0 Ribonuclease 2-5A BRE1 PF08647.6 CEP17518.1 - 6.3 6.8 20.1 5 7.1 7.4 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Init_tRNA_PT PF04179.7 CEP17518.1 - 6.3 5.5 10.0 7 5.3 6.9 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase ATP-synt_B PF00430.13 CEP17518.1 - 6.7 6.5 17.3 0.3 10.8 5.3 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Syntaxin PF00804.20 CEP17518.1 - 6.7 6.9 18.6 1.3 9.2 1.8 2.3 1 1 1 2 2 2 0 Syntaxin FlxA PF14282.1 CEP17518.1 - 6.9 6.6 20.0 4.4 7.2 5.7 3.0 1 1 2 3 3 3 0 FlxA-like protein KfrA_N PF11740.3 CEP17518.1 - 7 7.1 10.7 2.8 8.4 2.9 2.4 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term DNA_pol_alpha_N PF12254.3 CEP17518.1 - 7.1 6.5 9.7 0.92 9.3 1.9 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal Exonuc_VII_L PF02601.10 CEP17518.1 - 8.1 5.5 14.6 8.8 5.4 10.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.1 CEP17518.1 - 8.9 6.7 13.5 1.9 8.8 4.3 2.7 1 1 2 3 3 3 0 Snapin/Pallidin EAP30 PF04157.11 CEP17518.1 - 8.9 5.3 12.4 0.98 8.5 3.3 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family XhlA PF10779.4 CEP17518.1 - 9.1 6.2 25.9 5.7 6.9 5.6 2.4 1 1 1 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.11 CEP17518.1 - 9.7 4.6 8.6 2.6 6.5 3.9 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF221 PF02714.10 CEP17519.1 - 1.5e-73 247.5 22.7 3.2e-73 246.4 15.7 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEP17519.1 - 2.1e-18 66.3 2.2 2.1e-18 66.3 1.5 4.6 5 1 0 5 5 5 1 Late exocytosis, associated with Golgi transport RRM_6 PF14259.1 CEP17519.1 - 0.05 13.5 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 CEP17520.1 - 3.7e-05 23.3 1.7 8.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CEP17520.1 - 1.5 8.5 14.9 42 3.9 1.2 6.9 6 2 0 6 6 6 0 Leucine Rich repeats (2 copies) Pyr_redox PF00070.22 CEP17521.1 - 1.5e-16 60.5 0.0 3.5e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEP17521.1 - 9.8e-14 51.6 1.2 1.7e-11 44.3 0.8 4.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.14 CEP17521.1 - 2.2e-11 43.8 0.2 4.5e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.19 CEP17521.1 - 4.7e-09 35.6 0.0 0.037 12.9 0.0 3.8 2 2 1 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEP17521.1 - 5.8e-07 29.7 0.3 0.093 12.7 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP17521.1 - 2e-06 27.7 0.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CEP17521.1 - 7.2e-05 22.6 0.3 13 5.5 0.0 4.4 2 2 2 4 4 4 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CEP17521.1 - 0.0005 19.2 0.0 0.87 8.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.13 CEP17521.1 - 0.00092 19.2 0.1 0.68 9.9 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 CEP17521.1 - 0.0014 17.6 0.0 0.25 10.2 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.1 CEP17521.1 - 0.0028 16.6 0.3 1.2 8.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CEP17521.1 - 0.013 14.1 0.1 0.14 10.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase RGS-like PF09128.6 CEP17521.1 - 0.019 14.4 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain NAD_binding_7 PF13241.1 CEP17521.1 - 0.021 15.0 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 CEP17521.1 - 0.025 14.1 0.1 0.85 9.1 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 CEP17521.1 - 0.056 12.8 0.3 4.5 6.6 0.0 3.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 CEP17521.1 - 0.063 11.7 0.0 4.9 5.5 0.0 3.3 4 0 0 4 4 4 0 HI0933-like protein GIDA PF01134.17 CEP17521.1 - 0.066 12.0 0.1 4.4 6.0 0.0 3.3 4 0 0 4 4 4 0 Glucose inhibited division protein A Tim44 PF04280.10 CEP17522.1 - 1.3e-33 116.0 1.1 2.8e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain CHAD PF05235.9 CEP17522.1 - 0.092 12.3 2.3 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 CHAD domain DUF4041 PF13250.1 CEP17522.1 - 0.34 10.4 3.2 0.88 9.1 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) UEV PF05743.8 CEP17523.1 - 2.8e-26 91.5 0.6 1.3e-25 89.3 0.4 2.1 1 1 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CEP17523.1 - 1.2e-14 53.6 0.9 1.7e-13 49.9 0.0 2.7 3 0 0 3 3 3 1 Vps23 core domain Ribosomal_S4e PF00900.15 CEP17523.1 - 0.036 13.7 0.5 0.2 11.3 0.0 2.3 3 0 0 3 3 3 0 Ribosomal family S4e DUF1719 PF08224.6 CEP17524.1 - 0.039 13.0 0.0 0.091 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) ABC_tran PF00005.22 CEP17525.1 - 2.3e-45 154.2 0.5 7.3e-22 78.1 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CEP17525.1 - 1.6e-20 72.6 8.3 7.5e-20 70.5 2.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 CEP17525.1 - 1.1e-19 71.5 7.1 8.9e-05 22.5 0.4 4.3 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 CEP17525.1 - 2.7e-09 36.4 0.1 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CEP17525.1 - 5.2e-09 35.6 1.3 0.017 14.3 0.2 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CEP17525.1 - 1.3e-08 35.0 0.1 0.0019 18.3 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEP17525.1 - 1.5e-08 35.5 0.1 0.012 16.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CEP17525.1 - 1.5e-07 31.3 1.6 0.011 15.4 0.1 3.6 2 1 1 3 3 3 2 Dynamin family AAA_33 PF13671.1 CEP17525.1 - 7.4e-07 29.1 0.0 0.045 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CEP17525.1 - 1.3e-06 28.6 1.7 0.034 14.4 0.0 3.3 4 1 0 4 4 3 2 AAA domain AAA_15 PF13175.1 CEP17525.1 - 4.2e-06 26.0 3.2 0.64 8.9 0.0 4.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_23 PF13476.1 CEP17525.1 - 4.6e-06 27.0 8.9 0.029 14.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain Miro PF08477.8 CEP17525.1 - 5.3e-06 26.9 0.0 0.1 13.1 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_16 PF13191.1 CEP17525.1 - 6.9e-06 26.1 0.1 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 CEP17525.1 - 1.1e-05 25.2 0.1 0.76 9.6 0.0 4.3 3 1 1 4 4 4 1 AAA domain SbcCD_C PF13558.1 CEP17525.1 - 1.4e-05 24.8 0.1 0.049 13.5 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 CEP17525.1 - 1.8e-05 24.7 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CEP17525.1 - 5.5e-05 22.8 0.1 0.25 11.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 CEP17525.1 - 9e-05 22.0 4.7 0.04 13.3 0.0 3.6 3 1 0 4 4 4 1 AAA-like domain DUF258 PF03193.11 CEP17525.1 - 0.0001 21.5 0.0 0.053 12.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CEP17525.1 - 0.00014 21.3 0.0 0.49 9.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 CEP17525.1 - 0.00018 21.2 0.0 0.11 12.1 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CEP17525.1 - 0.00019 21.3 0.2 1.1 9.2 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 CEP17525.1 - 0.00042 20.4 0.1 1.4 9.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase ArgK PF03308.11 CEP17525.1 - 0.0014 17.5 0.0 0.29 9.8 0.0 2.6 2 0 0 2 2 2 1 ArgK protein VirE PF05272.6 CEP17525.1 - 0.0026 17.2 0.1 0.41 10.0 0.0 2.8 3 0 0 3 3 2 1 Virulence-associated protein E DUF87 PF01935.12 CEP17525.1 - 0.003 17.4 0.5 4.1 7.1 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 CEP17525.1 - 0.0041 16.7 0.0 0.29 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CEP17525.1 - 0.0043 17.2 0.0 0.58 10.3 0.0 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CEP17525.1 - 0.0045 16.7 0.2 6.7 6.3 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CEP17525.1 - 0.012 15.1 0.0 0.66 9.4 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 CEP17525.1 - 0.012 15.1 0.7 4.8 6.5 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 CEP17525.1 - 0.012 14.4 0.0 4 6.2 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 CEP17525.1 - 0.016 14.7 0.1 2.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 CEP17525.1 - 0.016 14.9 0.0 3.4 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) EIIA-man PF03610.11 CEP17525.1 - 0.022 14.7 0.9 0.27 11.3 0.2 2.8 3 0 0 3 3 3 0 PTS system fructose IIA component ATP_bind_1 PF03029.12 CEP17525.1 - 0.024 14.1 0.2 7.5 6.0 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 CEP17525.1 - 0.03 13.9 0.9 1.6 8.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.4 CEP17525.1 - 0.031 13.1 1.9 18 4.1 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Pox_A32 PF04665.7 CEP17525.1 - 0.033 13.4 0.0 9.2 5.4 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein DUF948 PF06103.6 CEP17525.1 - 0.037 13.8 0.0 0.15 11.9 0.0 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) T2SE PF00437.15 CEP17525.1 - 0.04 12.8 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 CEP17525.1 - 0.044 13.2 0.0 5.2 6.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.10 CEP17525.1 - 0.046 12.4 0.2 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 CEP17525.1 - 0.062 12.3 0.6 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin MarR_2 PF12802.2 CEP17525.1 - 0.082 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 MarR family Septin PF00735.13 CEP17525.1 - 0.083 11.8 0.7 6.1 5.7 0.0 2.5 3 0 0 3 3 2 0 Septin DUF3573 PF12097.3 CEP17525.1 - 0.084 11.4 0.1 0.084 11.4 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3573) AAA_13 PF13166.1 CEP17525.1 - 2.5 6.4 9.4 4.4 5.6 0.3 3.5 3 1 1 4 4 4 0 AAA domain DivIC PF04977.10 CEP17525.1 - 5.9 6.4 9.0 8.4 5.9 0.9 2.5 2 0 0 2 2 2 0 Septum formation initiator Pkinase PF00069.20 CEP17527.1 - 6.8e-73 245.0 0.0 8.6e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17527.1 - 2.1e-30 105.6 0.0 3e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP17527.1 - 2e-05 23.7 0.0 6e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP17527.1 - 0.00053 19.7 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP17527.1 - 0.011 14.7 0.0 0.072 12.0 0.0 1.9 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.17 CEP17527.1 - 0.069 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YqeY PF09424.5 CEP17528.1 - 7.7e-37 126.3 2.0 8.9e-37 126.1 1.4 1.0 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.13 CEP17528.1 - 0.092 12.4 1.0 7.5 6.2 0.0 2.6 1 1 1 2 2 2 0 GatB domain RabGAP-TBC PF00566.13 CEP17529.1 - 3.8e-44 150.7 1.2 7.2e-44 149.8 0.8 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 CEP17529.1 - 0.017 14.4 0.4 0.047 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3548) MBOAT PF03062.14 CEP17530.1 - 5.7e-30 104.5 30.9 5.7e-30 104.5 21.4 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CEP17530.1 - 9.6e-05 22.3 2.4 0.00033 20.6 1.7 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Plasmid_parti PF01672.11 CEP17530.1 - 0.093 13.1 0.1 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 Putative plasmid partition protein FAD_binding_7 PF03441.9 CEP17531.1 - 2.5e-76 256.5 0.5 4.2e-76 255.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase LMWPc PF01451.16 CEP17531.1 - 7.2e-39 133.2 0.0 1.3e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DNA_photolyase PF00875.13 CEP17531.1 - 8.1e-21 74.4 0.0 2.2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 DNA photolyase Nucleoporin_C PF03177.9 CEP17532.1 - 0.0006 18.4 0.1 0.0006 18.4 0.1 2.2 1 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal COQ9 PF08511.6 CEP17532.1 - 0.015 14.7 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 COQ9 EF-hand_1 PF00036.27 CEP17533.1 - 3e-14 51.1 9.5 2.6e-05 23.2 0.0 5.0 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.1 CEP17533.1 - 5.5e-12 44.4 7.7 0.00014 21.4 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CEP17533.1 - 3.2e-11 43.2 5.6 3.6e-06 27.0 0.3 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CEP17533.1 - 4.8e-10 38.9 8.0 4.9e-08 32.4 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CEP17533.1 - 8.5e-10 37.5 3.7 0.00033 19.8 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CEP17533.1 - 0.03 14.2 0.1 2.8 7.9 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain E1-E2_ATPase PF00122.15 CEP17534.1 - 4.8e-58 195.9 2.3 4.8e-58 195.9 1.6 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP17534.1 - 2.5e-44 150.9 12.9 2.5e-44 150.9 8.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP17534.1 - 5.5e-28 98.8 0.0 1.6e-27 97.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP17534.1 - 7.3e-21 73.9 0.0 1.5e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP17534.1 - 6.6e-15 55.7 0.0 1.7e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP17534.1 - 1.5e-09 37.1 0.0 3.8e-07 29.4 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP17534.1 - 1.6e-05 24.6 0.3 0.00062 19.4 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 CEP17534.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) UPF0061 PF02696.9 CEP17535.1 - 1.6e-114 382.9 0.0 2e-114 382.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family gag-asp_proteas PF13975.1 CEP17537.1 - 0.0079 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CEP17537.1 - 0.036 14.5 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.22 CEP17538.1 - 6.7e-09 35.4 0.5 4.3e-08 32.7 0.3 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP17539.1 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PAS PF00989.19 CEP17545.1 - 7.3e-12 45.0 0.1 2.3e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 CEP17545.1 - 3.1e-09 36.7 0.0 8.3e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CEP17545.1 - 5.5e-08 33.1 0.0 0.00098 19.4 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 CEP17545.1 - 4.2e-07 29.9 0.0 0.00078 19.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 CEP17545.1 - 1.7e-06 27.9 0.1 9.5e-06 25.5 0.0 2.1 3 0 0 3 3 3 1 PAS domain PAS_2 PF08446.6 CEP17545.1 - 0.00042 20.7 0.0 0.12 12.8 0.0 2.4 2 1 0 2 2 2 2 PAS fold DUF556 PF04476.8 CEP17545.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF556) G6PD_C PF02781.11 CEP17546.1 - 5.2e-124 412.8 0.1 1.7e-123 411.2 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CEP17546.1 - 4.1e-60 203.1 0.4 7.7e-60 202.2 0.1 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CEP17546.1 - 0.12 12.9 0.0 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Mitofilin PF09731.4 CEP17547.1 - 8.4e-97 325.1 25.9 1.5e-96 324.3 17.9 1.4 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Nsp1_C PF05064.8 CEP17547.1 - 0.0027 17.3 0.4 0.0027 17.3 0.3 3.3 4 1 0 4 4 4 1 Nsp1-like C-terminal region MFS_1 PF07690.11 CEP17548.1 - 0.0046 15.7 13.7 0.13 10.9 6.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.7 CEP17548.1 - 0.036 13.9 1.2 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Abhydrolase_3 PF07859.8 CEP17549.1 - 4.4e-66 222.4 0.0 5.3e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP17549.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CEP17549.1 - 6.8e-06 25.0 0.3 4.1e-05 22.5 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 CEP17549.1 - 2.2e-05 23.2 0.0 3.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) AXE1 PF05448.7 CEP17549.1 - 0.00028 19.4 0.0 0.00051 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 CEP17549.1 - 0.032 13.0 0.1 0.047 12.4 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 CEP17549.1 - 0.039 12.8 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.8 CEP17549.1 - 0.079 11.2 0.1 0.19 9.9 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.16 CEP17549.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 CEP17549.1 - 0.15 11.4 0.2 3.9 6.8 0.1 2.2 1 1 0 1 1 1 0 Putative esterase LSM PF01423.17 CEP17550.1 - 6.7e-16 57.5 0.0 9.8e-16 57.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEP17550.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain KTSC PF13619.1 CEP17550.1 - 0.091 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 KTSC domain HSF_DNA-bind PF00447.12 CEP17551.1 - 1.8e-37 127.6 1.9 1.8e-37 127.6 1.3 3.0 4 1 0 4 4 4 1 HSF-type DNA-binding Cob_adeno_trans PF01923.13 CEP17551.1 - 0.47 10.2 3.3 0.17 11.6 0.3 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase E1-E2_ATPase PF00122.15 CEP17552.1 - 2e-44 151.3 13.7 1.2e-29 103.0 0.1 3.3 2 1 1 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.21 CEP17552.1 - 3e-36 125.8 0.4 1.1e-34 120.6 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP17552.1 - 6.8e-21 74.0 0.1 1.4e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP17552.1 - 2.4e-18 67.0 0.0 5.5e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CEP17552.1 - 5.1e-12 45.6 0.1 5.1e-12 45.6 0.1 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 CEP17552.1 - 1.7e-11 43.4 0.4 4.3e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP17552.1 - 9.5e-07 28.6 0.6 0.00013 21.6 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.21 CEP17554.1 - 4e-09 36.2 12.9 0.00011 22.3 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP17554.1 - 6.1e-07 29.4 0.3 6.1e-07 29.4 0.2 4.2 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP17554.1 - 1.4e-05 25.0 10.8 0.013 15.8 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP17554.1 - 0.0063 16.6 3.5 0.023 14.8 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Gp-FAR-1 PF05823.7 CEP17554.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) zf-Di19 PF05605.7 CEP17554.1 - 0.055 13.5 0.5 0.14 12.2 0.4 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 CEP17554.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.10 CEP17554.1 - 0.12 12.1 3.3 3.2 7.5 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 CEP17554.1 - 0.57 10.4 3.9 1.8 8.9 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CEP17554.1 - 6 6.9 7.7 39 4.3 0.5 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger VTC PF09359.5 CEP17555.1 - 2.6e-105 351.4 0.1 3.6e-105 351.0 0.1 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEP17555.1 - 1.5e-25 90.5 3.3 2.8e-07 30.6 0.0 4.3 2 2 2 4 4 4 3 SPX domain DUF202 PF02656.10 CEP17555.1 - 2.2e-13 50.2 0.2 4.6e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF1673 PF07895.6 CEP17555.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) ECH PF00378.15 CEP17556.1 - 1.6e-25 89.6 0.0 2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CEP17556.1 - 0.007 16.1 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 bZIP_1 PF00170.16 CEP17557.1 - 1.7e-07 31.0 23.9 3.8e-05 23.5 16.6 2.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP17557.1 - 0.025 14.3 23.9 0.15 11.9 7.0 2.5 1 1 1 2 2 2 0 Basic region leucine zipper KfrA_N PF11740.3 CEP17557.1 - 0.056 13.8 4.2 0.11 12.9 2.9 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Atg14 PF10186.4 CEP17557.1 - 0.062 12.2 8.7 0.093 11.6 6.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 CEP17557.1 - 0.15 12.3 7.2 0.3 11.4 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 CEP17557.1 - 1.6 8.2 7.7 2.8 7.5 5.4 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 CEP17557.1 - 3.8 7.0 12.7 3.7 7.1 7.2 2.1 1 1 1 2 2 2 0 Septum formation initiator UPF0242 PF06785.6 CEP17557.1 - 8 5.0 10.2 13 4.3 7.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Ytp1 PF10355.4 CEP17558.1 - 3.3e-18 65.8 7.6 9.8e-17 61.0 5.3 2.9 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Ni_hydr_CYTB PF01292.15 CEP17558.1 - 0.00082 18.8 11.8 0.0035 16.7 0.1 3.1 2 1 1 3 3 3 2 Prokaryotic cytochrome b561 Neurensin PF14927.1 CEP17558.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.7 4 0 0 4 4 4 0 Neurensin UCR_TM PF02921.9 CEP17559.1 - 5.3e-20 71.4 1.4 1.1e-19 70.3 1.0 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CEP17559.1 - 4.8e-18 64.5 0.1 8.2e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PIF1 PF05970.9 CEP17560.1 - 1.7e-22 79.8 0.0 2.5e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase FAM219A PF15260.1 CEP17560.1 - 0.053 13.8 0.1 0.16 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein family FAM219A DUF3336 PF11815.3 CEP17561.1 - 1.5e-40 138.0 5.9 2.9e-40 137.0 4.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CEP17561.1 - 1.5e-18 67.4 0.0 4.7e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase OrfB_Zn_ribbon PF07282.6 CEP17562.1 - 0.0019 17.7 2.6 0.055 13.1 1.8 2.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain PyrI_C PF02748.10 CEP17562.1 - 0.48 9.8 2.3 1.3 8.4 1.5 1.8 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Phasin_2 PF09361.5 CEP17563.1 - 0.023 14.7 1.9 0.033 14.1 1.3 1.3 1 0 0 1 1 1 0 Phasin protein YlbD_coat PF14071.1 CEP17563.1 - 0.064 13.3 2.1 0.14 12.2 1.5 1.6 1 1 0 1 1 1 0 Putative coat protein MSV199 PF10553.4 CEP17563.1 - 0.087 12.7 0.7 0.12 12.2 0.5 1.3 1 0 0 1 1 1 0 MSV199 domain Nt_Gln_amidase PF09764.4 CEP17564.1 - 0.00098 18.4 0.1 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal glutamine amidase Asp-B-Hydro_N PF05279.6 CEP17564.1 - 0.071 12.9 5.7 0.12 12.1 3.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDE_3 PF13358.1 CEP17565.1 - 4.2e-18 65.5 0.0 5.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_2 PF12796.2 CEP17566.1 - 9.3e-35 118.8 1.4 1.4e-11 44.5 0.3 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CEP17566.1 - 2.5e-23 80.6 1.3 2.1e-06 27.2 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 CEP17566.1 - 5.6e-19 66.3 0.7 0.0014 18.6 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CEP17566.1 - 8.3e-17 61.2 0.5 6e-08 33.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP17566.1 - 1.8e-13 50.2 3.6 0.00027 21.0 0.0 5.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) GrpE PF01025.14 CEP17566.1 - 0.02 14.4 1.5 0.048 13.2 1.0 1.7 1 0 0 1 1 1 0 GrpE IncA PF04156.9 CEP17566.1 - 0.18 11.3 5.1 0.38 10.3 3.5 1.5 1 0 0 1 1 1 0 IncA protein CD52 PF15116.1 CEP17567.1 - 0.61 9.9 0.0 0.61 9.9 0.0 3.1 3 1 0 3 3 3 0 CAMPATH-1 antigen CGGC PF08821.6 CEP17568.1 - 0.0093 16.0 2.4 0.026 14.6 1.6 1.8 1 0 0 1 1 1 1 CGGC domain Tropomyosin PF00261.15 CEP17569.1 - 0.0053 15.8 11.6 0.0053 15.8 8.0 4.2 4 1 0 4 4 4 2 Tropomyosin Endonuclease_NS PF01223.18 CEP17570.1 - 6.1e-62 208.9 0.4 7.3e-62 208.6 0.3 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-TRAF PF02176.13 CEP17571.1 - 6e-16 58.5 28.4 1.9e-10 40.9 3.3 3.9 1 1 3 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 CEP17571.1 - 2.6e-07 30.5 11.4 2.6e-07 30.5 7.9 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP17571.1 - 5.9e-07 29.2 10.5 5.9e-07 29.2 7.3 3.0 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP17571.1 - 5.9e-06 25.8 7.0 5.9e-06 25.8 4.8 3.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP17571.1 - 7.8e-06 25.4 11.7 7.8e-06 25.4 8.1 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEP17571.1 - 1.4e-05 25.1 8.1 1.4e-05 25.1 5.6 3.6 2 2 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CEP17571.1 - 6.9e-05 22.4 8.2 6.9e-05 22.4 5.7 3.2 2 1 0 2 2 1 1 zinc-RING finger domain zf-Nse PF11789.3 CEP17571.1 - 7.6e-05 22.1 5.4 7.6e-05 22.1 3.8 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CEP17571.1 - 0.00056 19.8 0.6 0.024 14.5 0.0 3.0 2 1 1 3 3 3 1 U-box domain zf-C3HC4_4 PF15227.1 CEP17571.1 - 0.0011 18.7 11.8 0.0011 18.7 8.2 2.7 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP17571.1 - 0.0026 17.4 6.6 0.0026 17.4 4.5 2.6 2 1 1 3 3 3 1 RING-type zinc-finger Sina PF03145.11 CEP17571.1 - 0.0033 17.1 19.2 0.089 12.4 1.6 3.5 1 1 1 3 3 3 2 Seven in absentia protein family TBPIP PF07106.8 CEP17571.1 - 0.023 14.2 6.1 1.3 8.5 0.7 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Dad3 PF08656.5 CEP17571.1 - 0.029 14.0 1.4 0.029 14.0 1.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 HALZ PF02183.13 CEP17571.1 - 0.039 13.6 13.1 0.54 10.0 0.6 3.8 2 1 0 3 3 3 0 Homeobox associated leucine zipper AP4E_app_platf PF14807.1 CEP17571.1 - 0.047 13.9 0.1 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform FemAB PF02388.11 CEP17571.1 - 0.1 11.2 1.9 1 7.9 0.3 2.1 2 0 0 2 2 2 0 FemAB family DUF1664 PF07889.7 CEP17571.1 - 0.17 11.6 2.3 8.2 6.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-HC2 PF13490.1 CEP17571.1 - 0.89 9.5 8.4 4 7.4 0.0 4.7 5 0 0 5 5 5 0 Putative zinc-finger CENP-H PF05837.7 CEP17571.1 - 1.1 9.4 13.7 0.15 12.2 3.3 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) zf-RING_6 PF14835.1 CEP17571.1 - 2.8 7.7 11.6 0.076 12.8 3.0 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DivIC PF04977.10 CEP17571.1 - 6.1 6.4 8.0 14 5.2 0.6 2.5 2 0 0 2 2 2 0 Septum formation initiator PAH PF02671.16 CEP17572.1 - 3.5e-50 167.3 0.8 8.4e-19 66.9 0.4 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CEP17572.1 - 1.4e-36 124.2 2.0 2.5e-36 123.4 0.0 2.6 3 0 0 3 3 3 1 Sin3 family co-repressor Nop14 PF04147.7 CEP17572.1 - 0.00023 19.2 32.2 0.00023 19.2 22.3 2.7 3 0 0 3 3 3 1 Nop14-like family CDC45 PF02724.9 CEP17572.1 - 0.0043 15.1 27.1 0.0095 14.0 18.8 1.5 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 CEP17572.1 - 0.68 8.9 37.7 0.048 12.7 22.0 2.2 2 0 0 2 2 2 0 BUD22 Trypan_PARP PF05887.6 CEP17572.1 - 5.8 6.7 14.5 12 5.6 10.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EMG1 PF03587.9 CEP17574.1 - 3.7e-76 254.9 0.3 4.5e-76 254.6 0.2 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ank_2 PF12796.2 CEP17575.1 - 2.1e-15 56.8 0.0 3.5e-07 30.4 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEP17575.1 - 2.3e-08 33.4 0.0 0.047 13.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CEP17575.1 - 4.1e-05 23.4 0.2 20 5.8 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 CEP17575.1 - 8.3e-05 22.7 0.0 0.022 14.9 0.0 3.4 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP17575.1 - 0.00017 21.9 0.2 0.034 14.6 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3996 PF13161.1 CEP17576.1 - 0.084 12.5 0.9 0.11 12.1 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3996) Fasciclin PF02469.17 CEP17577.1 - 2e-17 63.4 3.4 6.5e-10 39.0 0.1 2.4 2 0 0 2 2 2 2 Fasciclin domain PTH2 PF01981.11 CEP17580.1 - 9.4e-08 31.7 0.1 1.2e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 IL34 PF15036.1 CEP17580.1 - 0.048 13.2 0.1 0.072 12.6 0.1 1.3 1 1 0 1 1 1 0 Interleukin 34 TRM PF02005.11 CEP17581.1 - 8.6e-133 442.8 0.1 1.1e-132 442.5 0.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CEP17581.1 - 0.00052 19.6 0.0 0.00098 18.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 CEP17581.1 - 0.0045 16.3 0.0 0.0093 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CEP17581.1 - 0.04 13.5 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.10 CEP17581.1 - 0.049 13.0 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PX PF00787.19 CEP17582.1 - 1e-26 92.9 0.0 1.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 PX domain Methyltransf_23 PF13489.1 CEP17583.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 CEP17583.1 - 0.13 11.9 0.0 0.42 10.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain zf-CCCH_2 PF14608.1 CEP17583.1 - 3.1 7.9 6.0 0.86 9.7 1.3 2.4 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type MoCF_biosynth PF00994.19 CEP17584.1 - 1.3e-20 73.2 0.1 3.5e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain Nucleotid_trans PF03407.11 CEP17585.1 - 3.9e-25 88.8 0.9 5.8e-25 88.3 0.6 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sec7 PF01369.15 CEP17586.1 - 3.9e-39 134.2 0.1 1.2e-38 132.6 0.1 1.8 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CEP17586.1 - 2.3e-34 118.0 1.3 8.6e-34 116.2 0.9 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEP17586.1 - 1.9e-07 31.2 0.1 4.8e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 PH domain Peptidase_S8 PF00082.17 CEP17587.1 - 1.6e-45 155.4 7.1 1.6e-45 155.4 4.9 1.8 2 0 0 2 2 2 1 Subtilase family PA PF02225.17 CEP17587.1 - 4.4e-11 42.3 0.1 1.3e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 CEP17587.1 - 4.5e-11 43.1 0.4 1.1e-10 41.8 0.3 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) UDPGP PF01704.13 CEP17588.1 - 1.8e-61 207.9 0.0 2.4e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CEP17588.1 - 0.06 13.4 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Arrestin_N PF00339.24 CEP17589.1 - 1.7e-10 40.9 0.0 1.1e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP17589.1 - 1.7e-10 41.1 0.1 4.1e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 CEP17589.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like Toxin_16 PF07945.6 CEP17590.1 - 0.067 12.8 0.4 0.067 12.8 0.3 2.3 2 0 0 2 2 2 0 Janus-atracotoxin AMP-binding PF00501.23 CEP17591.1 - 2.5e-18 65.6 0.1 9.1e-15 53.9 0.1 2.7 3 1 0 3 3 3 2 AMP-binding enzyme Glyco_hydro_47 PF01532.15 CEP17592.1 - 1.9e-154 514.7 0.7 2.2e-154 514.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FHIPEP PF00771.15 CEP17594.1 - 7.3 4.7 6.0 0.67 8.2 0.5 1.8 2 0 0 2 2 2 0 FHIPEP family bZIP_1 PF00170.16 CEP17595.1 - 5.2e-07 29.5 5.3 5.2e-07 29.5 3.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP17595.1 - 7.2e-07 28.9 5.2 7.2e-07 28.9 3.6 3.2 2 1 2 4 4 4 1 Basic region leucine zipper bZIP_Maf PF03131.12 CEP17595.1 - 0.0063 16.7 4.6 0.0063 16.7 3.2 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor APG6 PF04111.7 CEP17595.1 - 2.2 7.2 15.4 2.9 6.8 10.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TCO89 PF10452.4 CEP17596.1 - 2.5e-12 46.5 7.2 2.5e-12 46.5 5.0 2.4 1 1 2 3 3 3 1 TORC1 subunit TCO89 Bud13 PF09736.4 CEP17596.1 - 1.2 9.3 8.3 9.1 6.5 0.3 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex WD40 PF00400.27 CEP17597.1 - 3.9e-14 51.9 0.1 0.00027 20.6 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 CEP17597.1 - 6.9e-05 22.6 1.4 0.027 14.2 0.2 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kinesin PF00225.18 CEP17598.1 - 1.2e-93 313.4 3.3 1.2e-93 313.4 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain SAM_2 PF07647.12 CEP17598.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEP17598.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_L35Ae PF01247.13 CEP17599.1 - 1.4e-41 140.1 1.4 1.6e-41 139.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CEP17599.1 - 0.0021 17.9 0.1 0.35 10.8 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain GSHPx PF00255.14 CEP17601.1 - 1.6e-42 143.2 0.2 2.3e-42 142.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CEP17601.1 - 9.8e-07 28.5 0.5 2.6e-06 27.1 0.3 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEP17601.1 - 0.00014 21.4 0.4 0.00077 19.0 0.3 2.1 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 CEP17601.1 - 0.073 13.1 0.0 0.3 11.1 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Lipase_3 PF01764.20 CEP17602.1 - 1.7e-13 50.4 0.0 3e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.25 CEP17602.1 - 4e-05 23.3 0.2 0.00011 21.9 0.0 1.9 2 0 0 2 2 2 1 C2 domain zf-RVT PF13966.1 CEP17604.1 - 0.02 15.2 1.0 0.04 14.2 0.7 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase F-box PF00646.28 CEP17605.1 - 2.1e-07 30.3 0.0 7.7e-07 28.6 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEP17605.1 - 1.1e-05 25.0 0.1 2.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CEP17605.1 - 0.0087 15.6 9.0 0.91 9.2 0.2 5.7 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) DUF2538 PF10804.3 CEP17605.1 - 0.027 14.3 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) Recep_L_domain PF01030.19 CEP17606.1 - 2.3e-09 37.1 5.5 0.0061 16.5 0.9 4.9 1 1 3 4 4 4 4 Receptor L domain DUF3971 PF13116.1 CEP17606.1 - 0.0043 16.4 4.4 0.6 9.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function Urease_alpha PF00449.15 CEP17606.1 - 0.072 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain F-box-like PF12937.2 CEP17607.1 - 0.014 15.1 0.1 0.05 13.3 0.1 2.1 1 0 0 1 1 1 0 F-box-like SPX PF03105.14 CEP17608.1 - 6.2e-40 137.7 7.1 9.5e-40 137.0 4.9 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CEP17608.1 - 3.6e-32 111.8 27.9 5e-32 111.3 19.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CEP17608.1 - 2.4e-16 59.2 33.7 8.1e-14 50.9 11.5 2.3 1 1 1 2 2 2 2 Citrate transporter DrrA_P4M PF14860.1 CEP17608.1 - 0.29 10.8 2.2 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain RicinB_lectin_2 PF14200.1 CEP17609.1 - 6.7e-05 23.2 0.0 0.023 15.0 0.0 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CEP17609.1 - 0.00031 20.7 0.1 0.57 10.2 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain MAPKK1_Int PF08923.5 CEP17610.1 - 2.1e-28 98.3 0.3 2.5e-28 98.1 0.2 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting OrfB_Zn_ribbon PF07282.6 CEP17611.1 - 3.6e-08 32.9 0.2 9.3e-08 31.6 0.1 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Proteasome PF00227.21 CEP17612.1 - 9.2e-50 168.5 0.1 1.1e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Rad60-SLD PF11976.3 CEP17613.1 - 1.2e-24 85.7 0.0 1.5e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CEP17613.1 - 7.2e-10 38.1 0.0 9.2e-10 37.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family SCO1-SenC PF02630.9 CEP17614.1 - 1.1e-55 187.9 0.2 1.6e-55 187.4 0.2 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CEP17614.1 - 0.0025 17.4 0.0 0.0049 16.5 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family RE_HaeII PF09554.5 CEP17614.1 - 0.019 14.0 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 HaeII restriction endonuclease FMN_red PF03358.10 CEP17616.1 - 0.00034 20.1 0.0 0.002 17.6 0.0 2.1 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Nup84_Nup100 PF04121.8 CEP17617.1 - 8.6e-38 129.5 19.1 2.1e-30 105.0 5.0 2.5 1 1 0 2 2 2 2 Nuclear pore protein 84 / 107 CorA PF01544.13 CEP17618.1 - 2e-45 155.0 13.2 4e-28 98.3 1.0 2.6 2 1 1 3 3 3 2 CorA-like Mg2+ transporter protein Metallophos PF00149.23 CEP17620.1 - 8.1e-20 71.0 1.9 1.2e-19 70.4 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP17620.1 - 0.0031 17.3 1.4 0.0095 15.7 0.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Adaptin_N PF01602.15 CEP17621.1 - 8.7e-118 393.9 8.7 1.3e-117 393.3 6.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CEP17621.1 - 8.6e-11 41.9 5.1 4.3e-05 23.4 0.1 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CEP17621.1 - 2.1e-08 34.3 0.3 0.00062 19.9 0.0 4.8 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 CEP17621.1 - 0.00016 21.5 3.2 2.6 8.3 0.0 5.9 7 0 0 7 7 7 1 HEAT repeat AP4E_app_platf PF14807.1 CEP17621.1 - 0.0012 19.0 0.4 0.006 16.7 0.3 2.3 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform BLVR PF06375.6 CEP17621.1 - 0.0028 17.5 0.3 0.0028 17.5 0.2 5.4 2 1 3 5 5 5 2 Bovine leukaemia virus receptor (BLVR) VPS9 PF02204.13 CEP17622.1 - 2e-32 111.2 0.0 2e-32 111.2 0.0 2.3 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain p47_phox_C PF08944.6 CEP17622.1 - 0.087 13.0 4.6 0.043 13.9 1.2 2.1 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain ACBP PF00887.14 CEP17623.1 - 4e-24 84.1 0.6 4.9e-24 83.8 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein HalX PF08663.5 CEP17623.1 - 0.18 11.8 1.0 0.27 11.2 0.2 1.6 2 0 0 2 2 2 0 HalX domain Peptidase_M24 PF00557.19 CEP17624.1 - 5.2e-54 182.9 0.0 6.6e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CEP17624.1 - 2.4e-14 52.8 0.0 1.7e-12 46.8 0.0 2.3 1 1 1 2 2 2 2 Aminopeptidase P, N-terminal domain Dus PF01207.12 CEP17625.1 - 6.9e-58 195.9 0.0 1.1e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NAD_Gly3P_dh_C PF07479.9 CEP17626.1 - 7.2e-55 184.8 0.0 1e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CEP17626.1 - 1.5e-50 170.9 0.0 2.6e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus WHG PF13305.1 CEP17627.1 - 0.085 13.4 0.1 0.85 10.2 0.0 2.6 3 0 0 3 3 3 0 WHG domain SH3_1 PF00018.23 CEP17628.1 - 7.1e-28 95.7 0.0 1.6e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CEP17628.1 - 7.1e-17 60.7 0.0 3.7e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CEP17628.1 - 5e-15 54.7 0.0 7.3e-08 31.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 CEP17628.1 - 1e-08 34.9 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 CEP17628.1 - 3.3e-05 23.4 0.1 8.6e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 PB1 domain IncA PF04156.9 CEP17629.1 - 0.35 10.4 4.9 0.87 9.1 3.4 1.8 1 1 0 1 1 1 0 IncA protein SHMT PF00464.14 CEP17630.1 - 8.2e-200 663.2 0.6 8.4e-198 656.6 0.4 2.0 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CEP17630.1 - 0.1 11.6 0.0 0.25 10.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CEP17630.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L18e PF00828.14 CEP17631.1 - 2.9e-25 89.1 0.1 7.3e-25 87.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 NNMT_PNMT_TEMT PF01234.12 CEP17631.1 - 0.041 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF21 PF01595.15 CEP17632.1 - 1.4e-32 112.4 0.9 7.2e-32 110.1 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 CEP17632.1 - 2.1e-07 30.6 0.1 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain BTB PF00651.26 CEP17633.1 - 8.8e-07 28.9 0.0 1.2e-05 25.2 0.0 2.8 2 0 0 2 2 2 1 BTB/POZ domain DUF258 PF03193.11 CEP17634.1 - 0.0013 17.9 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CEP17634.1 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 CEP17634.1 - 0.0024 17.8 0.1 0.033 14.1 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ArgK PF03308.11 CEP17634.1 - 0.0043 15.8 0.0 0.02 13.7 0.0 1.9 2 0 0 2 2 2 1 ArgK protein DUF2146 PF10220.4 CEP17634.1 - 0.0058 14.6 0.0 0.008 14.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2146) ABC_tran PF00005.22 CEP17634.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 CEP17634.1 - 0.012 16.1 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 CEP17634.1 - 0.015 15.2 0.0 0.078 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CEP17634.1 - 0.021 13.6 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 CEP17634.1 - 0.034 14.9 0.0 0.2 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CEP17634.1 - 0.06 13.6 0.9 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 CEP17634.1 - 0.064 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Ras family AAA_22 PF13401.1 CEP17634.1 - 0.078 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CEP17634.1 - 0.14 12.5 0.8 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CEP17634.1 - 0.17 11.4 0.1 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pterin_4a PF01329.14 CEP17634.1 - 0.26 11.0 1.2 6.3 6.6 0.1 2.4 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase Sas10_Utp3 PF04000.10 CEP17635.1 - 3.6e-18 65.5 1.8 9.6e-18 64.1 1.2 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family AKNA PF12443.3 CEP17635.1 - 0.16 11.9 3.0 0.13 12.3 0.3 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor Kelch_4 PF13418.1 CEP17636.1 - 3.1e-28 97.2 6.8 2.4e-07 30.4 0.1 6.6 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP17636.1 - 4.3e-28 96.7 3.0 2.2e-06 27.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 CEP17636.1 - 3.3e-27 93.9 0.5 4.2e-05 23.5 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 CEP17636.1 - 5.6e-26 89.8 0.4 6.3e-07 28.8 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CEP17636.1 - 4.1e-23 80.5 4.6 4.5e-05 23.4 0.3 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CEP17636.1 - 4.7e-13 48.3 1.6 0.00016 21.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Syndecan PF01034.15 CEP17638.1 - 0.0024 17.4 0.4 0.0051 16.4 0.2 1.5 1 0 0 1 1 1 1 Syndecan domain DUF1191 PF06697.7 CEP17638.1 - 0.027 13.3 0.1 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CcmD PF04995.9 CEP17638.1 - 0.09 12.5 0.3 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) EphA2_TM PF14575.1 CEP17638.1 - 0.14 12.5 1.4 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain THUMP PF02926.12 CEP17639.1 - 5.7e-16 58.7 0.0 1.2e-15 57.6 0.0 1.6 1 1 1 2 2 2 1 THUMP domain Peptidase_M76 PF09768.4 CEP17640.1 - 3.9e-68 228.2 7.7 6.5e-68 227.5 5.3 1.4 1 0 0 1 1 1 1 Peptidase M76 family DEAD PF00270.24 CEP17640.1 - 4.7e-44 149.8 0.0 8.7e-43 145.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP17640.1 - 4.6e-28 96.8 0.0 1.5e-27 95.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP17640.1 - 0.014 15.1 0.0 0.052 13.3 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CEP17640.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF460 PF04312.8 CEP17640.1 - 0.2 11.2 0.0 0.5 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF460) TB2_DP1_HVA22 PF03134.14 CEP17641.1 - 2.8e-33 113.5 5.9 3.8e-33 113.0 4.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Aa_trans PF01490.13 CEP17641.1 - 0.026 13.0 0.4 0.033 12.6 0.3 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Pkinase PF00069.20 CEP17643.1 - 5.3e-44 150.3 0.2 1.2e-43 149.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.7 CEP17643.1 - 3.7e-42 143.2 0.5 1.1e-41 141.6 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 CEP17643.1 - 1.2e-24 86.8 0.0 1.6e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.1 CEP17643.1 - 1.9e-05 24.2 0.0 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 CEP17643.1 - 0.014 14.9 0.4 0.13 11.8 0.0 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat Transcrip_reg PF01709.15 CEP17644.1 - 1.6e-68 230.3 11.7 1.5e-62 210.8 2.7 2.1 1 1 1 2 2 2 2 Transcriptional regulator Pkinase PF00069.20 CEP17645.1 - 1.7e-74 250.2 0.0 3.1e-74 249.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17645.1 - 1.9e-37 128.7 0.0 3.5e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.17 CEP17645.1 - 2.6e-24 85.7 4.7 2.6e-24 85.7 3.3 1.6 2 0 0 2 2 2 1 ZIP Zinc transporter APH PF01636.18 CEP17645.1 - 2.8e-06 27.2 0.1 0.036 13.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEP17645.1 - 0.0033 16.5 0.2 0.0065 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CEP17645.1 - 0.018 14.6 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 CEP17645.1 - 0.066 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF4203 PF13886.1 CEP17645.1 - 0.72 9.2 13.7 0.37 10.2 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) WWE PF02825.15 CEP17647.1 - 1.3e-05 24.4 0.2 1.4e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 WWE domain MHC_I_C PF06623.6 CEP17648.1 - 0.018 14.5 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 MHC_I C-terminus DUF2435 PF10363.4 CEP17650.1 - 7e-24 83.5 0.1 3.2e-23 81.4 0.0 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 CEP17650.1 - 1.8e-09 36.8 2.3 3e-09 36.1 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) HEAT_2 PF13646.1 CEP17650.1 - 5.9e-05 23.2 3.1 1.3 9.3 0.0 5.0 4 1 2 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.2 CEP17650.1 - 0.013 15.8 0.4 11 6.5 0.0 3.5 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region DNA_topoisoIV PF00521.15 CEP17651.1 - 2.6e-114 382.4 0.0 4.9e-114 381.4 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CEP17651.1 - 1.5e-34 118.6 0.3 3.7e-34 117.4 0.2 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CEP17651.1 - 8.1e-12 44.9 0.0 3.5e-11 42.9 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CEP17651.1 - 8.4e-11 41.5 0.0 2.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVT_1 PF00078.22 CEP17652.1 - 1.3e-25 90.0 0.0 2.6e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.23 CEP17653.1 - 1.7e-99 333.0 0.0 2.1e-99 332.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP17653.1 - 7.3e-18 65.2 0.0 1.9e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 CEP17654.1 - 4.3e-72 242.3 0.0 7.3e-72 241.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17654.1 - 8.4e-34 116.8 0.0 1.3e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP17654.1 - 0.028 14.1 0.6 0.068 12.8 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CEP17654.1 - 0.094 11.5 0.1 0.19 10.5 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Na_H_Exchanger PF00999.16 CEP17655.1 - 8.5e-67 225.3 46.7 1.2e-66 224.8 32.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-DHHC PF01529.15 CEP17656.1 - 1.7e-39 135.0 9.5 1.7e-39 135.0 6.6 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase FYVE PF01363.16 CEP17656.1 - 0.21 11.5 6.5 0.52 10.2 4.5 1.7 1 0 0 1 1 1 0 FYVE zinc finger DUF3273 PF11677.3 CEP17656.1 - 1.3 8.2 4.4 0.18 11.0 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3273) Tim17 PF02466.14 CEP17657.1 - 4.8e-25 88.0 6.5 6.2e-25 87.7 4.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2457 PF10446.4 CEP17658.1 - 0.0086 14.8 1.8 0.0086 14.8 1.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Prok-TraM PF09228.5 CEP17658.1 - 0.13 12.4 6.8 0.33 11.1 4.7 1.6 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM BAF1_ABF1 PF04684.8 CEP17658.1 - 0.2 10.4 22.8 1.2 7.8 0.4 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF3417 PF11897.3 CEP17658.1 - 0.26 11.2 5.0 0.49 10.3 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) TSA PF03249.8 CEP17658.1 - 0.42 9.0 4.8 0.73 8.3 3.3 1.3 1 0 0 1 1 1 0 Type specific antigen RXT2_N PF08595.6 CEP17658.1 - 0.63 9.8 11.3 0.43 10.3 1.3 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF3987 PF13148.1 CEP17658.1 - 1.2 7.6 12.3 3.4 6.1 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) Afi1 PF07792.7 CEP17658.1 - 1.4 8.8 9.0 4.7 7.2 2.7 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_S49_N PF08496.5 CEP17658.1 - 1.9 8.2 7.4 3.4 7.4 5.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4358 PF14270.1 CEP17658.1 - 2.9 7.8 6.7 5.6 6.8 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) FYDLN_acid PF09538.5 CEP17658.1 - 5.2 7.7 13.4 11 6.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Spt5_N PF11942.3 CEP17658.1 - 8.3 7.1 19.3 4.9 7.8 4.3 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CSD PF00313.17 CEP17659.1 - 8e-21 73.5 0.4 1.4e-20 72.8 0.3 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CEP17659.1 - 0.042 13.3 0.1 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain PH_4 PF15404.1 CEP17660.1 - 4.9e-13 49.0 13.9 8.7e-11 41.6 3.3 4.7 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 CEP17660.1 - 1.4e-07 31.6 21.3 0.0044 17.2 2.7 5.4 3 3 0 3 3 3 3 PH domain PH_6 PF15406.1 CEP17660.1 - 0.065 13.2 0.6 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain Hydrolase_3 PF08282.7 CEP17660.1 - 0.52 9.8 3.1 0.95 8.9 1.6 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HALZ PF02183.13 CEP17661.1 - 0.001 18.7 1.0 0.0053 16.4 0.7 2.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper MIT PF04212.13 CEP17661.1 - 0.033 14.0 0.6 0.033 14.0 0.4 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 CEP17661.1 - 0.052 13.4 2.0 0.09 12.7 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PhoU PF01895.14 CEP17661.1 - 0.67 10.4 3.5 1 9.8 0.3 2.7 2 1 0 2 2 2 0 PhoU domain DUF972 PF06156.8 CEP17661.1 - 1.2 9.5 15.7 2.6 8.4 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 CEP17661.1 - 3.4 7.0 19.4 0.053 12.9 6.4 2.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 TSC22 PF01166.13 CEP17661.1 - 5 7.1 13.2 5.8 6.9 0.1 3.7 3 1 0 3 3 3 0 TSC-22/dip/bun family Ax_dynein_light PF10211.4 CEP17661.1 - 5.1 6.8 22.5 0.09 12.6 5.7 3.1 2 1 1 3 3 3 0 Axonemal dynein light chain RabGAP-TBC PF00566.13 CEP17662.1 - 9e-33 113.5 0.2 9e-33 113.5 0.2 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PDGLE PF13190.1 CEP17663.1 - 0.00038 20.0 0.3 0.00081 19.0 0.2 1.6 1 0 0 1 1 1 1 PDGLE domain EphA2_TM PF14575.1 CEP17663.1 - 0.00075 19.8 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 CEP17663.1 - 0.0022 16.8 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 CEP17663.1 - 0.0042 16.6 0.2 0.0087 15.6 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain Podoplanin PF05808.6 CEP17663.1 - 0.009 15.5 0.5 0.019 14.5 0.4 1.6 1 0 0 1 1 1 1 Podoplanin Plasmodium_Vir PF05795.6 CEP17663.1 - 0.0096 15.1 0.1 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein YajC PF02699.10 CEP17663.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Herpes_gE PF02480.11 CEP17663.1 - 0.034 12.4 0.0 0.052 11.8 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CcmD PF04995.9 CEP17663.1 - 0.052 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1517 PF07466.6 CEP17663.1 - 0.081 11.8 0.3 0.16 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Yip1 PF04893.12 CEP17663.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain RCR PF12273.3 CEP17663.1 - 0.78 10.3 3.7 15 6.1 0.0 3.0 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red HhH-GPD PF00730.20 CEP17664.1 - 1.8e-18 66.8 0.0 3.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CEP17664.1 - 2.1e-06 27.1 0.0 5.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CEP17664.1 - 0.004 17.2 3.9 0.0075 16.4 2.7 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Put_Phosphatase PF06888.7 CEP17665.1 - 1.6e-42 145.3 0.4 1.9e-42 145.0 0.3 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 CEP17665.1 - 2.2e-05 24.6 0.1 4.5e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP17665.1 - 0.047 13.9 0.1 0.095 12.9 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HLH PF00010.21 CEP17666.1 - 1.6e-09 37.3 2.2 2.9e-09 36.4 0.6 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Med25_VWA PF11265.3 CEP17666.1 - 0.036 13.0 0.0 0.064 12.2 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A CBP4 PF07960.6 CEP17666.1 - 0.86 9.2 8.2 2.4 7.7 0.3 2.5 2 1 0 2 2 2 0 CBP4 Glycos_transf_1 PF00534.15 CEP17667.1 - 9e-17 61.0 0.0 1.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CEP17667.1 - 1.4e-15 57.4 0.0 3.2e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 CEP17667.1 - 0.0023 18.1 0.0 0.023 14.8 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CEP17667.1 - 0.056 13.1 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sld5 PF05916.6 CEP17668.1 - 7.3e-21 74.4 0.8 1.1e-20 73.9 0.5 1.2 1 0 0 1 1 1 1 GINS complex protein TPR_19 PF14559.1 CEP17669.1 - 2.1e-19 69.5 14.2 1.5e-06 28.4 0.0 7.7 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 CEP17669.1 - 1.6e-17 62.2 17.8 2.2e-06 27.0 0.0 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 CEP17669.1 - 3e-17 62.0 17.6 3.5e-07 29.7 0.0 7.5 5 2 2 7 7 7 4 TPR repeat TPR_14 PF13428.1 CEP17669.1 - 1.4e-15 56.3 12.2 0.0049 17.3 0.1 8.5 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP17669.1 - 6.1e-15 53.8 23.4 9.9e-06 25.0 0.0 9.3 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 CEP17669.1 - 6.5e-15 54.0 3.1 0.086 13.0 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP17669.1 - 1.5e-14 54.1 10.4 1.8e-05 25.3 0.1 6.9 6 2 1 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP17669.1 - 3.6e-11 43.0 11.3 0.071 13.2 0.1 7.1 7 1 0 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CEP17669.1 - 8e-11 40.9 8.0 0.0025 17.4 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.9 CEP17669.1 - 2.6e-09 36.6 5.2 0.025 14.9 0.1 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP17669.1 - 3.9e-09 36.3 16.4 0.0023 17.8 0.0 8.4 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP17669.1 - 2.3e-06 26.9 13.9 0.01 15.5 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEP17669.1 - 7.9e-06 26.0 16.1 3.4 8.3 0.0 8.0 9 0 0 9 9 7 2 Tetratricopeptide repeat NARP1 PF12569.3 CEP17669.1 - 0.00022 20.1 0.3 0.51 9.0 0.0 3.3 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 DUF3682 PF12446.3 CEP17669.1 - 0.00025 21.3 10.8 0.00059 20.1 7.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) TPR_20 PF14561.1 CEP17669.1 - 0.00026 21.0 1.0 0.6 10.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CEP17669.1 - 0.0021 17.8 9.8 1.9 8.3 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat APC8 PF04049.8 CEP17669.1 - 0.0034 17.0 1.4 0.0064 16.2 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_21 PF09976.4 CEP17669.1 - 0.0047 16.8 0.1 0.0047 16.8 0.1 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CEP17669.1 - 0.079 12.0 0.0 0.079 12.0 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEP17669.1 - 0.15 12.0 5.4 39 4.3 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ARID PF01388.16 CEP17670.1 - 4e-20 71.4 0.0 8.3e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C2H2 PF00096.21 CEP17670.1 - 0.097 13.0 6.2 1.4 9.4 0.4 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase PF00069.20 CEP17671.1 - 1.6e-54 184.7 0.2 1.6e-54 184.7 0.2 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17671.1 - 1.2e-22 80.2 0.0 2.1e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP17671.1 - 0.001 18.8 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CEP17671.1 - 0.0037 16.6 1.7 0.059 12.7 1.2 2.4 1 1 0 1 1 1 1 RIO1 family zf-C2H2 PF00096.21 CEP17672.1 - 1e-10 41.3 24.2 1.3e-05 25.2 0.3 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP17672.1 - 4.4e-09 36.1 19.7 1.6e-06 28.1 1.0 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP17672.1 - 6.3e-05 23.0 19.8 0.0012 19.0 0.1 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP17672.1 - 0.0025 17.6 0.1 2 8.4 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger C2 PF00168.25 CEP17674.1 - 3.4e-17 62.0 0.0 9.6e-17 60.6 0.0 1.9 2 0 0 2 2 2 1 C2 domain Membr_traf_MHD PF10540.4 CEP17674.1 - 1.7e-14 53.7 1.6 6.1e-14 51.9 0.1 2.7 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.6 CEP17674.1 - 3.6e-07 28.8 2.5 2.4e-06 26.1 0.1 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF810) Septin PF00735.13 CEP17675.1 - 4.7e-56 189.8 0.7 5.3e-38 130.6 0.1 2.6 2 1 0 2 2 2 2 Septin MMR_HSR1 PF01926.18 CEP17675.1 - 1.4e-05 25.0 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEP17675.1 - 0.00013 21.8 0.7 0.052 13.3 0.0 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 CEP17675.1 - 0.00048 19.6 0.0 0.016 14.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CEP17675.1 - 0.0024 17.9 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CEP17675.1 - 0.0025 17.2 0.1 0.0087 15.5 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 CEP17675.1 - 0.0034 17.2 0.0 0.0088 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CEP17675.1 - 0.0041 16.7 0.4 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 CEP17675.1 - 0.0041 17.5 0.3 0.014 15.8 0.1 2.0 1 1 1 2 2 2 1 Miro-like protein cobW PF02492.14 CEP17675.1 - 0.0055 16.1 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CEP17675.1 - 0.0085 15.8 0.1 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CEP17675.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CEP17675.1 - 0.023 14.8 0.0 0.2 11.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 CEP17675.1 - 0.024 14.1 0.5 0.47 9.9 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CEP17675.1 - 0.076 12.5 0.4 3.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 CEP17675.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CEP17675.1 - 0.12 11.7 0.0 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Glyco_transf_49 PF13896.1 CEP17676.1 - 1.3e-41 142.7 0.8 5.6e-34 117.6 0.3 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CEP17676.1 - 0.011 14.7 0.0 0.025 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEP17676.1 - 0.089 12.4 0.1 0.49 10.0 0.1 2.3 1 1 1 2 2 2 0 Glycosyl transferase family 2 Mob1_phocein PF03637.12 CEP17677.1 - 7.4e-41 139.7 0.2 9.4e-41 139.3 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family CRM1_C PF08767.6 CEP17678.1 - 4.6e-124 413.4 3.1 1.9e-123 411.4 0.0 3.0 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 CEP17678.1 - 2.8e-34 118.1 12.2 4e-34 117.6 2.6 4.3 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 CEP17678.1 - 6.8e-10 38.7 2.1 2.9e-09 36.7 1.5 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain C8 PF08742.6 CEP17678.1 - 0.049 13.8 1.1 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 C8 domain Ral PF11058.3 CEP17678.1 - 0.15 11.4 3.2 0.16 11.3 0.5 2.3 2 0 0 2 2 2 0 Antirestriction protein Ral Vac14_Fab1_bd PF12755.2 CEP17678.1 - 0.16 12.4 1.7 2.7 8.4 0.0 3.7 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HLH PF00010.21 CEP17679.1 - 1.5e-11 43.8 0.1 3.5e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ndc1_Nup PF09531.5 CEP17680.1 - 4e-59 200.5 5.0 5.6e-59 200.1 3.5 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Glyco_transf_15 PF01793.11 CEP17680.1 - 1.4e-38 132.7 6.0 5.9e-29 101.0 1.7 2.2 1 1 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase RGS PF00615.14 CEP17681.1 - 2.9e-05 24.1 0.1 0.00011 22.2 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2868 PF11067.3 CEP17681.1 - 0.0021 17.2 0.0 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2868) MRAP PF15183.1 CEP17681.1 - 0.019 14.5 2.8 0.042 13.4 1.9 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF2892 PF11127.3 CEP17681.1 - 0.028 14.2 0.3 0.058 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Arm PF00514.18 CEP17682.1 - 4.3e-70 229.3 24.7 2e-12 46.4 0.1 10.6 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEP17682.1 - 3e-26 91.5 15.7 4.6e-06 26.8 0.2 7.0 2 2 2 5 5 5 5 HEAT repeats HEAT PF02985.17 CEP17682.1 - 1.5e-15 55.7 18.1 0.017 15.1 0.0 9.2 9 0 0 9 9 9 4 HEAT repeat Adaptin_N PF01602.15 CEP17682.1 - 2.8e-15 55.6 11.0 2.5e-11 42.6 0.9 2.3 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 CEP17682.1 - 3.6e-15 55.9 16.9 0.015 15.7 0.1 8.2 6 1 2 8 8 8 5 HEAT-like repeat KAP PF05804.7 CEP17682.1 - 9.3e-12 43.6 3.2 2.1e-11 42.4 2.2 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CEP17682.1 - 1.9e-11 43.6 8.9 0.0011 18.1 0.1 4.0 1 1 2 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.9 CEP17682.1 - 8.5e-07 28.3 5.3 0.0042 16.2 3.4 3.4 1 1 1 2 2 2 2 V-ATPase subunit H Cnd1 PF12717.2 CEP17682.1 - 9.7e-07 28.7 4.4 0.00027 20.8 0.3 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CEP17682.1 - 0.00069 19.9 0.8 9 6.7 0.0 4.4 3 2 2 5 5 4 1 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 CEP17682.1 - 0.0086 15.9 10.8 0.74 9.7 0.3 5.1 3 2 3 6 6 6 1 V-ATPase subunit H Ribosomal_L2_C PF03947.13 CEP17682.1 - 0.072 12.8 0.3 2.3 8.0 0.0 3.0 2 1 1 3 3 3 0 Ribosomal Proteins L2, C-terminal domain Fer4_12 PF13353.1 CEP17682.1 - 0.093 12.8 0.5 0.22 11.6 0.1 1.8 2 0 0 2 2 1 0 4Fe-4S single cluster domain HEAT_PBS PF03130.11 CEP17682.1 - 0.14 12.6 13.0 84 4.0 0.0 7.4 7 1 0 7 7 6 0 PBS lyase HEAT-like repeat Sec62 PF03839.11 CEP17683.1 - 2.4e-44 151.4 1.2 3.8e-44 150.7 0.8 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 Tfb4 PF03850.9 CEP17684.1 - 1e-93 313.6 0.3 1.3e-93 313.2 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Phosducin PF02114.11 CEP17685.1 - 4.4e-21 74.7 0.5 5.3e-21 74.5 0.3 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 CEP17685.1 - 0.00029 20.4 0.1 0.00058 19.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin RRS1 PF04939.7 CEP17685.1 - 1.2 8.6 5.0 0.52 9.7 1.7 1.7 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) PI3_PI4_kinase PF00454.22 CEP17686.1 - 7.4e-51 172.8 0.0 1.9e-50 171.5 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CEP17686.1 - 5.9e-12 44.8 0.2 1.6e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 FATC domain Rapamycin_bind PF08771.6 CEP17686.1 - 0.00079 19.4 2.6 0.031 14.3 0.1 3.7 1 1 1 2 2 2 1 Rapamycin binding domain HEAT PF02985.17 CEP17686.1 - 0.0049 16.8 0.6 0.86 9.8 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CEP17686.1 - 0.025 14.8 0.2 7.1 6.9 0.0 4.6 6 0 0 6 6 6 0 HEAT repeats CAP_GLY PF01302.20 CEP17691.1 - 4.9e-21 74.2 0.3 7.7e-21 73.5 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Metallophos PF00149.23 CEP17692.1 - 9.2e-42 142.7 0.7 1.2e-41 142.3 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3684 PF12449.3 CEP17692.1 - 0.062 10.8 0.1 0.082 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Ribosomal_L18e PF00828.14 CEP17694.1 - 2.7e-24 85.9 0.6 2.7e-24 85.9 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 DDE_3 PF13358.1 CEP17695.1 - 8.6e-06 25.5 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_24 PF13412.1 CEP17695.1 - 0.0054 16.0 0.1 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 CEP17695.1 - 0.0064 16.0 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Pox_A32 PF04665.7 CEP17696.1 - 0.045 13.0 0.4 0.13 11.4 0.1 1.8 1 1 1 2 2 2 0 Poxvirus A32 protein Pox_H7 PF04787.7 CEP17696.1 - 0.077 12.7 1.5 0.1 12.3 0.8 1.3 1 1 0 1 1 1 0 Late protein H7 Arch_flagellin PF01917.11 CEP17696.1 - 6.4 6.3 7.1 13 5.3 4.9 1.6 1 1 0 1 1 1 0 Archaebacterial flagellin BioT2 PF15368.1 CEP17697.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 Spermatogenesis family BioT2 Sec8_exocyst PF04048.9 CEP17697.1 - 0.089 12.4 0.2 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain RNA_pol_L PF01193.19 CEP17700.1 - 0.02 14.0 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain GCR1_C PF12550.3 CEP17702.1 - 7.2e-20 70.6 0.0 1.9e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF4200 PF13863.1 CEP17703.1 - 0.0039 17.1 2.3 0.0075 16.2 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Na_trans_assoc PF06512.8 CEP17703.1 - 0.058 13.3 0.1 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated PIF1 PF05970.9 CEP17704.1 - 3.6e-13 49.1 0.2 4.5e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Retrotrans_gag PF03732.12 CEP17705.1 - 0.0031 17.5 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 CEP17706.1 - 9.3e-16 58.0 0.0 2.6e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CEP17706.1 - 0.00015 21.0 1.4 0.00041 19.7 1.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Chromo PF00385.19 CEP17707.1 - 7.4e-09 35.1 0.2 1e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 CEP17709.1 - 4.9e-07 29.0 0.0 6.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 GCR1_C PF12550.3 CEP17712.1 - 1.7e-05 24.5 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_29 PF13551.1 CEP17713.1 - 0.00073 19.6 0.1 0.0024 17.9 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP17713.1 - 0.004 17.9 0.0 0.004 17.9 0.0 3.0 4 0 0 4 4 4 1 Homeodomain-like domain Inhibitor_Mig-6 PF11555.3 CEP17714.1 - 9.8 6.6 7.7 0.93 9.9 2.0 1.8 2 1 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Cyc-maltodext_C PF10438.4 CEP17715.1 - 0.34 11.0 3.7 3.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain Period_C PF12114.3 CEP17715.1 - 2 7.9 7.4 2.5 7.6 5.1 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Asp_protease_2 PF13650.1 CEP17716.1 - 5.5e-05 23.6 0.0 0.00015 22.1 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease IFT20 PF14931.1 CEP17719.1 - 6.5 6.6 10.5 0.18 11.6 1.2 2.7 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 WD40 PF00400.27 CEP17720.1 - 3.5e-10 39.3 10.9 9.2e-06 25.3 0.0 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 CEP17720.1 - 5.9e-08 32.6 0.2 0.05 13.3 0.0 4.1 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A CENP-Q PF13094.1 CEP17720.1 - 0.0039 17.2 1.7 0.068 13.1 1.9 2.2 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit CASP_C PF08172.7 CEP17720.1 - 0.041 12.8 4.0 0.071 12.1 2.8 1.4 1 0 0 1 1 1 0 CASP C terminal IFT57 PF10498.4 CEP17720.1 - 0.081 11.6 3.4 0.13 10.9 2.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RRM_1 PF00076.17 CEP17721.1 - 2e-55 184.3 0.4 1.1e-19 69.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17721.1 - 6.5e-43 144.5 0.8 4.1e-13 49.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP17721.1 - 3.5e-29 100.4 0.4 1.9e-09 37.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP17721.1 - 0.0082 15.9 0.1 8.8 6.1 0.0 3.4 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 CEP17721.1 - 0.068 12.6 0.1 15 5.1 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 CEP17721.1 - 0.069 12.9 0.2 2.9 7.6 0.1 3.1 3 0 0 3 3 3 0 Limkain b1 Ras PF00071.17 CEP17722.1 - 2.9e-54 182.8 0.0 3.3e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP17722.1 - 5e-17 62.4 0.0 6.4e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP17722.1 - 3.7e-10 39.3 0.0 4.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP17722.1 - 5.3e-05 22.4 0.0 6.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEP17722.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 CEP17722.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CEP17722.1 - 0.098 12.1 0.1 0.28 10.6 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Homoserine_dh PF00742.14 CEP17723.1 - 5.7e-49 166.1 0.0 1e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CEP17723.1 - 1.7e-19 70.3 0.0 3.2e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CEP17723.1 - 0.0013 18.9 0.0 0.0046 17.2 0.0 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CEP17723.1 - 0.0028 17.5 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 CEP17723.1 - 0.0054 17.2 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_9 PF13454.1 CEP17723.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding IGPS PF00218.16 CEP17723.1 - 0.078 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Pkinase PF00069.20 CEP17724.1 - 2.1e-25 89.3 0.0 3.6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17724.1 - 1e-14 54.2 0.0 1.8e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF962 PF06127.6 CEP17725.1 - 3.1e-31 107.1 0.1 3.7e-31 106.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Tecti-min-caps PF09300.5 CEP17725.1 - 0.056 13.2 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Tectiviridae, minor capsid DUF1212 PF06738.7 CEP17727.1 - 2.8e-32 111.7 22.6 3.8e-32 111.3 0.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) PPI_Ypi1 PF07491.6 CEP17727.1 - 3.8e-23 80.8 5.4 8.4e-23 79.7 3.7 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor DUF3815 PF12821.2 CEP17727.1 - 1.2e-15 57.5 35.9 9.6e-14 51.4 12.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) CDC45 PF02724.9 CEP17727.1 - 0.0026 15.9 1.1 0.0036 15.4 0.8 1.1 1 0 0 1 1 1 1 CDC45-like protein SR-25 PF10500.4 CEP17727.1 - 0.025 14.0 4.4 0.048 13.1 3.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OCIA PF07051.6 CEP17727.1 - 0.18 11.2 0.6 0.51 9.7 0.4 1.7 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) DBP10CT PF08147.7 CEP17728.1 - 0.01 15.6 0.2 0.38 10.6 0.0 2.5 2 0 0 2 2 2 0 DBP10CT (NUC160) domain DUF2356 PF10189.4 CEP17729.1 - 1.7e-64 217.0 2.1 3.3e-64 216.0 0.2 2.4 3 0 0 3 3 3 1 Conserved protein (DUF2356) RVT_1 PF00078.22 CEP17731.1 - 1.6e-34 119.1 0.0 3.4e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP17731.1 - 7.8e-12 45.6 1.1 1.6e-11 44.5 0.8 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP17731.1 - 4.1e-07 29.6 0.0 9.5e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CEP17731.1 - 0.00043 20.5 0.6 0.0018 18.5 0.4 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase ImpE PF07024.8 CEP17731.1 - 0.058 13.3 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 ImpE protein FliT PF05400.8 CEP17731.1 - 2.2 8.7 4.8 3 8.3 2.5 1.8 2 0 0 2 2 2 0 Flagellar protein FliT zf-CCHC PF00098.18 CEP17732.1 - 9.4e-05 22.1 1.8 9.4e-05 22.1 1.3 3.4 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_6 PF15288.1 CEP17732.1 - 0.26 10.9 8.4 5.2 6.8 1.3 3.4 2 1 1 3 3 3 0 Zinc knuckle eIF3g PF12353.3 CEP17732.1 - 0.68 9.8 13.4 0.25 11.2 1.0 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 CEP17732.1 - 2.2 8.0 10.6 0.3 10.8 0.3 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEP17732.1 - 2.4 7.8 11.8 15 5.3 0.2 3.4 3 0 0 3 3 3 0 Zinc knuckle DUF2693 PF10902.3 CEP17736.1 - 0.051 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) Retrotrans_gag PF03732.12 CEP17737.1 - 6e-08 32.6 0.7 5.2e-07 29.6 0.0 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CEP17737.1 - 0.041 13.8 2.6 0.079 12.9 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Gag_spuma PF03276.9 CEP17737.1 - 0.055 11.8 4.3 0.09 11.0 3.0 1.3 1 0 0 1 1 1 0 Spumavirus gag protein DUF4187 PF13821.1 CEP17737.1 - 0.1 12.2 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-CCHC_4 PF14392.1 CEP17737.1 - 0.11 12.1 1.6 0.25 11.0 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle FYVE PF01363.16 CEP17740.1 - 1.7e-16 59.8 5.5 1.7e-16 59.8 3.8 3.3 3 1 0 3 3 3 1 FYVE zinc finger DUF3719 PF12516.3 CEP17740.1 - 0.046 13.2 0.0 0.26 10.8 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) zf-AN1 PF01428.11 CEP17740.1 - 2.7 7.9 12.7 0.8 9.6 5.8 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger HEAT_EZ PF13513.1 CEP17741.1 - 1.8e-20 72.8 15.8 1.1e-09 38.4 0.0 10.1 8 3 3 11 11 11 4 HEAT-like repeat HEAT PF02985.17 CEP17741.1 - 2.7e-19 67.4 9.2 0.0003 20.6 0.0 8.8 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.1 CEP17741.1 - 4.4e-17 62.1 1.8 2.9e-06 27.4 0.0 6.6 3 3 4 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.2 CEP17741.1 - 2.9e-14 53.2 0.5 0.057 13.7 0.0 7.5 6 2 3 9 9 9 4 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 CEP17741.1 - 3e-10 39.8 0.0 9.8e-10 38.2 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cnd1 PF12717.2 CEP17741.1 - 3.7e-07 30.1 0.1 0.0059 16.4 0.0 5.3 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 CEP17741.1 - 0.00074 18.3 0.4 0.36 9.5 0.0 3.2 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 CEP17741.1 - 0.0012 18.5 1.8 2.4 7.8 0.1 4.5 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 CEP17741.1 - 0.0012 18.2 0.1 3.5 6.8 0.0 4.7 4 2 1 5 5 5 1 CLASP N terminal Arm PF00514.18 CEP17741.1 - 0.0047 16.6 4.3 7.2 6.5 0.1 6.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat p450 PF00067.17 CEP17742.1 - 1.8e-61 208.0 0.1 2.1e-61 207.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 RFC1 PF08519.7 CEP17742.1 - 0.043 13.5 0.2 0.098 12.4 0.1 1.5 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Adaptin_N PF01602.15 CEP17744.1 - 3.4e-149 497.5 11.4 4.4e-149 497.1 7.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CEP17744.1 - 4e-30 104.9 5.5 4.7e-28 98.2 0.1 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CEP17744.1 - 1.1e-19 70.4 3.3 2.3e-10 40.5 0.1 5.2 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.17 CEP17744.1 - 2.3e-10 39.6 5.4 0.0042 17.0 0.0 5.9 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.1 CEP17744.1 - 1.7e-08 34.6 1.4 0.094 13.2 0.0 5.2 5 0 0 5 5 5 3 HEAT-like repeat Arm PF00514.18 CEP17744.1 - 1.3e-07 31.1 0.4 0.022 14.5 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 CEP17744.1 - 0.00024 20.2 0.2 0.35 9.7 0.0 3.0 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain RIX1 PF08167.7 CEP17744.1 - 0.0004 20.1 0.0 0.16 11.6 0.0 2.8 2 1 0 3 3 3 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 CEP17744.1 - 0.00059 19.2 0.9 2.4 7.4 0.1 3.6 2 1 1 3 3 3 2 CLASP N terminal RasGEF_N_2 PF14663.1 CEP17744.1 - 0.018 15.0 0.7 0.67 9.9 0.0 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FANCI_S2 PF14676.1 CEP17744.1 - 0.018 14.9 1.4 0.32 10.8 0.1 3.3 2 2 2 4 4 4 0 FANCI solenoid 2 Oxidored_q1_N PF00662.15 CEP17744.1 - 0.034 13.7 0.8 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus ParcG PF10274.4 CEP17744.1 - 0.043 13.7 4.8 0.15 11.9 0.0 3.5 3 1 0 4 4 4 0 Parkin co-regulated protein TatD_DNase PF01026.16 CEP17745.1 - 3.8e-35 121.3 0.0 4.8e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase RRM_1 PF00076.17 CEP17746.1 - 7.9e-18 63.8 0.0 1.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17746.1 - 3e-12 46.3 0.0 4.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP17746.1 - 8.1e-08 31.9 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Corona_nucleoca PF00937.13 CEP17746.1 - 0.15 10.9 5.9 0.21 10.5 4.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Mito_carr PF00153.22 CEP17747.1 - 1.6e-19 69.4 0.1 3.9e-06 26.4 0.0 4.9 5 0 0 5 5 5 4 Mitochondrial carrier protein Prenylcys_lyase PF07156.9 CEP17748.1 - 2.1e-39 135.4 0.0 2.7e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 CEP17748.1 - 4.4e-08 33.0 0.1 1.3e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CEP17748.1 - 5e-05 23.1 0.7 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 CEP17748.1 - 0.0003 19.8 0.5 0.0055 15.6 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 CEP17748.1 - 0.0015 17.7 0.1 0.0039 16.3 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 CEP17748.1 - 0.0031 17.3 0.3 0.41 10.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP17748.1 - 0.0062 16.6 0.1 3.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_2 PF02230.11 CEP17749.1 - 1.3e-21 77.0 0.0 1.7e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CEP17749.1 - 9.8e-10 38.3 0.0 1.8e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CEP17749.1 - 0.00028 20.4 0.0 0.00075 18.9 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CEP17749.1 - 0.0084 16.0 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family C2 PF00168.25 CEP17750.1 - 1.2e-56 188.5 9.6 9.7e-18 63.8 0.1 6.3 6 0 0 6 6 6 5 C2 domain SUZ PF12752.2 CEP17751.1 - 8.6e-05 22.9 2.1 8.6e-05 22.9 1.5 1.9 2 1 0 2 2 2 1 SUZ domain ABC_membrane_2 PF06472.10 CEP17752.1 - 6.6e-83 278.0 3.7 1.2e-82 277.2 2.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SCAMP PF04144.8 CEP17752.1 - 1.7e-34 119.2 13.3 1.7e-34 119.2 9.2 1.7 2 0 0 2 2 2 1 SCAMP family ABC_tran PF00005.22 CEP17752.1 - 2.1e-15 57.1 0.0 6.3e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 CEP17752.1 - 5.4e-05 23.3 0.1 0.066 13.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 CEP17752.1 - 0.005 16.5 0.0 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 CEP17752.1 - 0.011 15.9 0.1 0.04 14.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEP17752.1 - 0.011 14.7 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEP17752.1 - 0.019 14.9 3.1 0.036 14.0 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.16 CEP17752.1 - 0.039 13.1 0.1 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CEP17752.1 - 0.042 14.6 0.1 0.21 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CEP17752.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 CEP17752.1 - 0.98 9.7 2.9 6.5 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain MBOAT PF03062.14 CEP17753.1 - 1e-35 123.3 16.3 1e-35 123.3 11.3 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DPM3 PF08285.6 CEP17754.1 - 7.7e-32 109.0 0.0 8.5e-32 108.8 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1624 PF07786.7 CEP17754.1 - 0.015 14.6 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Ribosomal_S17e PF00833.13 CEP17755.1 - 2.6e-60 201.5 0.4 3.2e-60 201.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 CNH PF00780.17 CEP17756.1 - 8.7e-59 199.1 0.0 1.6e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEP17756.1 - 1.9e-36 125.6 0.9 3.4e-36 124.8 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 CEP17756.1 - 2.8e-23 82.3 0.0 7.4e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEP17756.1 - 0.043 14.0 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 PH domain LRR_4 PF12799.2 CEP17757.1 - 0.00033 20.2 9.3 1.3 8.7 0.0 5.3 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEP17757.1 - 0.00074 19.2 12.9 2.5 8.4 0.0 7.1 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 CEP17757.1 - 0.002 18.0 15.1 3.1 8.1 0.0 8.0 8 1 0 8 8 8 1 Leucine Rich repeat LRR_8 PF13855.1 CEP17757.1 - 0.0036 17.0 14.3 0.41 10.4 0.2 5.2 3 2 3 6 6 6 4 Leucine rich repeat DUF2411 PF10304.4 CEP17757.1 - 0.056 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) zf-C2H2_4 PF13894.1 CEP17759.1 - 0.0058 16.8 3.3 0.0058 16.8 2.3 3.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP17759.1 - 0.012 15.7 1.2 0.07 13.2 0.5 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RVT_3 PF13456.1 CEP17759.1 - 0.07 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like TFIID-18kDa PF02269.11 CEP17759.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit zf-met2 PF12907.2 CEP17759.1 - 0.075 13.0 3.7 0.25 11.3 2.6 1.9 1 0 0 1 1 1 0 Zinc-binding zf-C2H2 PF00096.21 CEP17759.1 - 2.7 8.5 17.0 0.23 11.8 2.9 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type RVT_1 PF00078.22 CEP17760.1 - 1.5e-22 80.0 0.0 1.9e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 CEP17762.1 - 1.1e-17 63.1 10.1 7.1e-08 32.0 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat RRM_3 PF08777.6 CEP17763.1 - 0.046 13.5 1.6 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 RNA binding motif Pribosyltran PF00156.22 CEP17764.1 - 1.2e-17 63.7 0.1 1.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CEP17764.1 - 0.0032 16.7 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 CEP17764.1 - 0.022 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 PRTase ComF-like TAP42 PF04177.7 CEP17765.1 - 1.8e-91 306.6 10.2 2e-91 306.4 7.1 1.0 1 0 0 1 1 1 1 TAP42-like family Matrilin_ccoil PF10393.4 CEP17765.1 - 0.015 14.6 0.4 0.54 9.6 0.1 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Trans_reg_C PF00486.23 CEP17765.1 - 0.12 12.2 0.2 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Transket_pyr PF02779.19 CEP17766.1 - 5.1e-62 208.5 0.0 7.7e-62 207.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CEP17766.1 - 3.4e-61 206.6 0.0 4.5e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component EF-hand_8 PF13833.1 CEP17767.1 - 7.3e-23 79.9 6.5 4.5e-10 38.9 0.2 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 CEP17767.1 - 6e-22 77.5 1.2 4.4e-15 55.5 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CEP17767.1 - 1.2e-19 67.9 7.4 1.7e-07 29.9 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CEP17767.1 - 3.1e-15 54.6 2.6 6.7e-05 22.4 0.2 4.2 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CEP17767.1 - 7.7e-13 47.1 7.9 0.0001 21.4 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CEP17767.1 - 3.8e-08 32.9 2.1 0.042 13.5 0.0 3.0 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CEP17767.1 - 1.5e-06 28.0 0.1 0.0031 17.4 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CEP17767.1 - 0.0011 18.9 0.0 0.099 12.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Tenui_NCP PF04876.7 CEP17767.1 - 0.008 15.7 0.2 0.88 9.0 0.0 2.1 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein Ribosomal_60s PF00428.14 CEP17767.1 - 0.01 16.1 0.4 0.13 12.6 0.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1456 PF07308.8 CEP17767.1 - 0.022 14.8 0.4 0.7 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Peptidase_U35_2 PF14550.1 CEP17767.1 - 0.068 12.7 0.2 0.26 10.9 0.1 1.8 1 1 1 2 2 2 0 Putative phage protease XkdF p25-alpha PF05517.7 CEP17767.1 - 0.1 12.8 0.6 0.4 10.9 0.4 1.9 1 1 1 2 2 2 0 p25-alpha PIF1 PF05970.9 CEP17768.1 - 2.3e-09 36.7 0.1 2.5e-09 36.5 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase PEPCK_ATP PF01293.15 CEP17769.1 - 1.3e-214 713.0 0.0 1.6e-214 712.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 CEP17769.1 - 0.16 11.9 0.0 0.84 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 CEP17769.1 - 0.2 11.4 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KilA-N PF04383.8 CEP17770.1 - 0.00051 19.6 0.0 0.0021 17.6 0.0 2.0 1 1 0 1 1 1 1 KilA-N domain Ribosomal_60s PF00428.14 CEP17770.1 - 0.2 12.0 9.3 0.71 10.3 3.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Arrestin_C PF02752.17 CEP17771.1 - 1.8e-12 47.4 7.4 3.9e-12 46.4 1.7 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP17771.1 - 4.2e-11 42.8 0.6 3.6e-06 26.8 0.1 3.2 2 2 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Alpha_adaptinC2 PF02883.15 CEP17771.1 - 0.0052 17.0 0.1 0.017 15.4 0.1 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain Rgp1 PF08737.5 CEP17771.1 - 0.079 12.0 4.4 1.7 7.6 0.2 2.4 2 1 1 3 3 3 0 Rgp1 Ribosomal_L17 PF01196.14 CEP17772.1 - 1.5e-37 128.0 1.2 7.4e-37 125.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 GCV_T PF01571.16 CEP17773.1 - 1.7e-21 76.6 0.0 4.1e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CEP17773.1 - 4.3e-08 33.0 0.0 8.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF367 PF04034.8 CEP17774.1 - 1.3e-48 163.7 0.0 1.9e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CEP17774.1 - 3.9e-10 39.1 0.9 6.7e-10 38.3 0.6 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Daxx PF03344.10 CEP17774.1 - 0.57 8.5 13.1 0.94 7.8 9.1 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CEP17774.1 - 1.1 7.0 20.5 1.5 6.6 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 CEP17774.1 - 1.3 8.8 15.6 2 8.1 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SCP2 PF02036.12 CEP17775.1 - 2.2e-23 82.4 1.1 2.8e-23 82.1 0.8 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CEP17775.1 - 0.0003 20.7 0.3 0.0004 20.3 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal COQ7 PF03232.8 CEP17776.1 - 3e-73 244.9 0.2 3.6e-73 244.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ldh_1_C PF02866.13 CEP17776.1 - 0.076 12.7 0.1 0.42 10.3 0.0 2.1 2 1 1 3 3 3 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain PNK3P PF08645.6 CEP17777.1 - 7.3e-59 197.7 0.5 1.4e-58 196.8 0.4 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CEP17777.1 - 7.8e-23 80.9 0.0 5.8e-22 78.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEP17777.1 - 4.1e-06 26.0 0.1 0.024 13.7 0.0 2.5 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.5 CEP17777.1 - 0.0015 17.7 2.3 0.61 9.2 0.0 2.3 1 1 0 2 2 2 2 Chromatin associated protein KTI12 Hydrolase_6 PF13344.1 CEP17777.1 - 0.0041 16.9 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 CEP17777.1 - 0.023 15.5 0.3 0.097 13.4 0.0 2.4 3 1 0 3 3 3 0 AAA domain HAD_2 PF13419.1 CEP17777.1 - 0.032 14.4 0.0 7.3 6.7 0.0 2.6 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase 6PF2K PF01591.13 CEP17777.1 - 0.046 12.8 0.3 0.74 8.8 0.0 2.5 2 1 1 3 3 3 0 6-phosphofructo-2-kinase PGP_phosphatase PF09419.5 CEP17777.1 - 0.046 13.0 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase HAD PF12710.2 CEP17777.1 - 0.11 12.6 0.1 0.28 11.3 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3832 PF12909.2 CEP17777.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) MOZART1 PF12554.3 CEP17778.1 - 2.6e-24 84.4 0.6 4.6e-24 83.6 0.4 1.5 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF768 PF05589.6 CEP17778.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Xan_ur_permease PF00860.15 CEP17779.1 - 1.6e-33 115.8 24.7 7.6e-32 110.2 17.1 2.6 1 1 0 1 1 1 1 Permease family ATP-grasp_4 PF13535.1 CEP17780.1 - 0.00074 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain WD40 PF00400.27 CEP17781.1 - 1.1e-55 183.5 12.8 3.7e-12 45.6 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CEP17781.1 - 6.7e-06 24.5 7.2 0.037 12.1 0.0 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 CEP17781.1 - 0.002 17.8 0.1 0.23 11.1 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CEP17781.1 - 0.0027 16.5 0.0 0.028 13.2 0.0 2.4 3 0 0 3 3 3 1 Coatomer WD associated region Coatomer_WDAD PF04053.9 CEP17782.1 - 1.1e-121 406.7 0.8 1.7e-121 406.1 0.5 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CEP17782.1 - 4e-117 391.3 0.4 5.4e-117 390.8 0.3 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus TPR_2 PF07719.12 CEP17782.1 - 0.086 12.7 0.9 1.8 8.6 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP17782.1 - 0.22 11.2 2.9 0.89 9.2 0.1 3.1 3 0 0 3 3 3 0 TPR repeat zf-RING_2 PF13639.1 CEP17783.1 - 2.2e-05 24.1 5.3 2.2e-05 24.1 3.7 2.1 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 CEP17783.1 - 2.3e-05 23.7 1.0 4.2e-05 22.9 0.7 1.4 1 0 0 1 1 1 1 SWIM zinc finger RINGv PF12906.2 CEP17783.1 - 0.0026 17.7 6.5 0.0026 17.7 4.5 2.0 2 0 0 2 2 1 1 RING-variant domain C1_1 PF00130.17 CEP17783.1 - 0.01 15.5 2.2 0.01 15.5 1.5 2.1 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_RING PF05883.6 CEP17783.1 - 0.055 13.2 1.7 0.1 12.4 1.2 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain AT_hook PF02178.14 CEP17783.1 - 0.056 13.1 6.2 0.3 10.8 4.3 2.4 1 0 0 1 1 1 0 AT hook motif PHD_2 PF13831.1 CEP17783.1 - 0.067 12.5 4.7 0.12 11.7 3.2 1.4 1 0 0 1 1 1 0 PHD-finger PHD PF00628.24 CEP17783.1 - 0.13 11.9 7.7 0.33 10.6 5.3 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 CEP17783.1 - 0.63 10.0 7.0 1.9 8.4 4.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.2 CEP17783.1 - 0.83 9.5 4.3 1.9 8.3 3.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-Apc11 PF12861.2 CEP17783.1 - 1.8 8.4 8.6 0.068 13.0 1.6 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CEP17783.1 - 7.3 6.7 16.0 0.16 12.0 5.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) p450 PF00067.17 CEP17784.1 - 2.7e-97 326.2 0.1 4.1e-97 325.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 CEP17784.1 - 4.1e-37 127.7 0.0 1.2e-36 126.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 CEP17784.1 - 8.3e-24 84.2 0.2 1.7e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CEP17784.1 - 1.6e-16 60.8 0.0 4.3e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SBP_bac_5 PF00496.17 CEP17784.1 - 0.0069 15.2 0.3 0.014 14.2 0.2 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle HSF_DNA-bind PF00447.12 CEP17785.1 - 2.9e-34 117.3 0.5 2.9e-34 117.3 0.3 2.7 2 0 0 2 2 2 1 HSF-type DNA-binding VIT1 PF01988.14 CEP17785.1 - 7.7 5.9 8.7 11 5.3 0.1 2.3 2 0 0 2 2 2 0 VIT family Glu_synthase PF01645.12 CEP17786.1 - 3.8e-158 526.2 0.7 4.3e-157 522.7 0.1 2.4 3 0 0 3 3 3 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CEP17786.1 - 9.3e-138 458.8 0.0 1.4e-137 458.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CEP17786.1 - 1.5e-121 405.1 0.0 2.6e-121 404.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 CEP17786.1 - 1.6e-63 213.3 0.7 2.7e-63 212.6 0.5 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CEP17786.1 - 4e-25 87.6 0.1 8.9e-25 86.4 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CEP17786.1 - 9.4e-20 71.3 0.1 4.1e-19 69.2 0.1 2.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP17786.1 - 5.6e-12 46.1 0.3 1.9e-05 24.8 0.1 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP17786.1 - 2.8e-09 36.8 0.0 9.1e-09 35.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEP17786.1 - 8.1e-07 29.3 0.2 0.00043 20.6 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CEP17786.1 - 1.2e-05 24.6 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 CEP17786.1 - 1.7e-05 23.9 0.2 0.00032 19.6 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CEP17786.1 - 2.7e-05 22.8 1.2 3.8e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 CEP17786.1 - 0.00011 22.3 0.0 0.19 12.0 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CEP17786.1 - 0.00044 19.2 0.2 0.0023 16.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 CEP17786.1 - 0.00099 18.7 0.1 0.005 16.4 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 CEP17786.1 - 0.0011 18.1 1.1 0.031 13.3 0.1 2.9 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.2 CEP17786.1 - 0.0014 17.7 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CEP17786.1 - 0.0018 17.3 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 CEP17786.1 - 0.008 15.9 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 CEP17786.1 - 0.0093 14.8 0.1 0.062 12.1 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 CEP17786.1 - 0.013 15.6 0.3 6.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GATase_6 PF13522.1 CEP17786.1 - 0.027 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain 2-Hacid_dh_C PF02826.14 CEP17786.1 - 0.065 12.3 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 CEP17786.1 - 0.092 12.5 0.1 0.36 10.5 0.0 2.1 2 0 0 2 2 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 CEP17786.1 - 0.096 12.0 0.0 0.29 10.5 0.0 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LSM14 PF12701.2 CEP17787.1 - 3.2e-34 116.6 2.6 1.1e-33 114.8 0.1 2.6 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 CEP17787.1 - 4.4e-10 40.0 10.6 4.4e-10 40.0 7.3 4.2 4 2 0 4 4 4 1 FDF domain SM-ATX PF14438.1 CEP17787.1 - 0.00011 22.1 0.0 0.0003 20.6 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 CEP17787.1 - 0.2 10.1 5.8 0.32 9.4 4.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) AAA_11 PF13086.1 CEP17788.1 - 3.2e-13 49.7 0.5 2.8e-12 46.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CEP17788.1 - 4.4e-13 49.0 0.1 1.2e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP17788.1 - 2.7e-07 30.2 0.0 1.1e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CEP17788.1 - 2.6e-05 23.9 0.0 6.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP17788.1 - 0.00012 22.1 0.0 0.00046 20.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP17788.1 - 0.00091 20.0 0.0 0.0025 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CEP17788.1 - 0.001 18.3 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 CEP17788.1 - 0.0016 18.5 0.0 0.005 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CEP17788.1 - 0.0022 17.7 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CEP17788.1 - 0.0027 17.8 0.0 0.029 14.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA PF00004.24 CEP17788.1 - 0.0029 17.8 0.0 0.0082 16.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CEP17788.1 - 0.003 16.9 0.0 0.01 15.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 CEP17788.1 - 0.01 15.7 0.1 0.051 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CEP17788.1 - 0.013 14.6 0.1 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CEP17788.1 - 0.017 14.5 0.1 0.049 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CEP17788.1 - 0.022 14.6 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 CEP17788.1 - 0.062 12.9 0.3 0.17 11.5 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.1 CEP17788.1 - 0.071 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.2 CEP17789.1 - 1.1e-23 82.3 34.4 3.3e-10 39.3 2.1 4.7 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP17789.1 - 4.2e-16 58.4 11.9 1.8e-10 40.3 2.4 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CEP17789.1 - 3.7e-12 44.4 11.2 0.19 11.9 0.1 6.2 5 0 0 5 5 5 5 Leucine Rich Repeat LRR_7 PF13504.1 CEP17789.1 - 6.3e-10 37.6 11.1 0.27 11.6 0.1 6.2 5 0 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 CEP17789.1 - 0.00013 21.6 9.2 0.37 10.9 0.1 4.8 4 0 0 4 4 4 3 Leucine Rich repeat DUF732 PF05305.9 CEP17789.1 - 0.52 10.4 5.9 2.4 8.2 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Ank_4 PF13637.1 CEP17790.1 - 2e-15 56.8 4.0 1.3e-08 35.1 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CEP17790.1 - 8.4e-14 50.5 5.2 3.1e-12 45.6 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CEP17790.1 - 1.6e-13 50.7 2.5 2.4e-13 50.1 1.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP17790.1 - 1.7e-10 40.7 0.6 4e-10 39.6 0.4 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP17790.1 - 2.3e-09 36.5 1.4 9.9e-08 31.5 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat RGS PF00615.14 CEP17791.1 - 6.3e-22 77.9 0.6 1.1e-20 73.8 0.4 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 CEP17791.1 - 1e-09 37.9 0.1 1.7e-06 27.6 0.0 3.3 3 1 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2457 PF10446.4 CEP17791.1 - 6.6 5.3 14.0 2.5 6.7 7.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PrmA PF06325.8 CEP17794.1 - 7.2e-13 48.3 0.3 7.2e-13 48.3 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CEP17794.1 - 2.1e-11 43.5 0.0 3.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CEP17794.1 - 1.1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CEP17794.1 - 1.1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 CEP17794.1 - 2.6e-07 31.1 0.1 4.5e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP17794.1 - 1e-06 28.3 0.2 1.6e-06 27.7 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CEP17794.1 - 2.5e-05 23.7 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 CEP17794.1 - 0.00016 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DUF43 PF01861.11 CEP17794.1 - 0.0015 17.5 0.6 0.0027 16.7 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_11 PF08241.7 CEP17794.1 - 0.0049 17.3 0.1 0.038 14.4 0.0 2.3 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP17794.1 - 0.0069 16.7 0.0 0.016 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP17794.1 - 0.011 16.1 1.0 0.028 14.8 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 CEP17794.1 - 0.025 14.2 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.11 CEP17794.1 - 0.031 13.3 0.7 0.31 10.0 0.0 2.0 1 1 0 2 2 2 0 N-6 DNA Methylase Methyltransf_16 PF10294.4 CEP17794.1 - 0.075 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase HSP70 PF00012.15 CEP17795.1 - 5.3e-272 903.1 9.5 6.1e-272 902.9 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP17795.1 - 1.4e-16 60.0 0.1 4e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CEP17795.1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CEP17795.1 - 0.0081 15.2 0.4 0.059 12.4 0.1 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase CK_II_beta PF01214.13 CEP17796.1 - 1.9e-67 226.3 2.8 3.8e-67 225.3 0.2 2.2 2 1 0 2 2 2 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 CEP17796.1 - 7.9 7.1 24.8 0.046 14.3 3.6 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Imm5 PF14423.1 CEP17797.1 - 0.081 12.5 1.6 0.16 11.5 0.1 2.0 2 0 0 2 2 2 0 Immunity protein Imm5 Vpu PF00558.14 CEP17797.1 - 0.58 9.7 4.7 9.7 5.8 0.5 2.5 2 0 0 2 2 2 0 Vpu protein Not1 PF04054.10 CEP17798.1 - 4.3e-136 453.7 5.9 4.3e-136 453.7 4.1 2.2 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CEP17798.1 - 1.3e-51 174.1 5.8 4.5e-51 172.3 4.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Suf PF05843.9 CEP17798.1 - 0.0039 16.9 9.0 0.0096 15.6 6.3 1.7 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) RGS PF00615.14 CEP17799.1 - 2.3e-06 27.6 0.4 1.3e-05 25.2 0.3 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF4234 PF14018.1 CEP17800.1 - 3.9 7.2 13.2 1.5 8.6 0.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) Chromo PF00385.19 CEP17801.1 - 3.5e-10 39.4 0.2 8.4e-10 38.1 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pex14_N PF04695.8 CEP17801.1 - 1.3 9.0 13.1 0.78 9.7 1.8 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3807 PF12720.2 CEP17801.1 - 4.6 7.3 17.9 6.7 6.8 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF92 PF01940.11 CEP17802.1 - 7.7e-61 205.1 4.8 9e-61 204.8 3.3 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF1430 PF07242.6 CEP17802.1 - 0.042 13.9 0.7 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Proteasome PF00227.21 CEP17803.1 - 5.7e-62 208.3 0.2 7e-62 208.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEP17803.1 - 8.3e-15 53.7 0.2 1.7e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF218 PF02698.12 CEP17804.1 - 0.069 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 DUF218 domain Beta_protein PF14350.1 CEP17805.1 - 0.042 13.0 0.5 0.064 12.4 0.3 1.2 1 0 0 1 1 1 0 Beta protein WD40 PF00400.27 CEP17806.1 - 2.3e-23 81.1 7.6 1.5e-06 27.8 0.3 9.0 9 0 0 9 9 9 5 WD domain, G-beta repeat PQQ_3 PF13570.1 CEP17806.1 - 0.85 9.9 2.5 33 4.9 0.1 4.3 4 0 0 4 4 4 0 PQQ-like domain NfrA_C PF13283.1 CEP17807.1 - 0.019 14.3 0.0 0.059 12.7 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage N adsorption protein A C-term S1 PF00575.18 CEP17807.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain Cys_Met_Meta_PP PF01053.15 CEP17808.1 - 4.3e-38 130.6 0.0 6e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CEP17808.1 - 0.004 16.1 0.0 0.0092 14.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Sugar_tr PF00083.19 CEP17809.1 - 8.2e-96 321.3 28.6 1.6e-93 313.7 19.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP17809.1 - 5.2e-33 114.2 29.2 1.2e-31 109.7 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FlgH PF02107.11 CEP17809.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein RNA_pol_I_TF PF04090.7 CEP17810.1 - 0.0012 18.1 0.9 0.007 15.6 0.0 2.5 3 1 0 3 3 3 1 RNA polymerase I specific initiation factor RNA_pol_Rpb1_3 PF04983.13 CEP17810.1 - 0.025 14.3 1.6 0.059 13.1 1.1 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 ADK PF00406.17 CEP17811.1 - 4.4e-60 201.9 0.0 6e-60 201.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CEP17811.1 - 7.9e-16 57.4 0.0 1.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CEP17811.1 - 0.0012 19.6 0.0 0.0031 18.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP17811.1 - 0.0037 17.1 0.0 0.0062 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP17811.1 - 0.0067 16.7 0.1 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CEP17811.1 - 0.096 11.7 0.3 0.23 10.5 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin SNF2_N PF00176.18 CEP17812.1 - 2e-73 246.8 0.0 5.7e-73 245.3 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP17812.1 - 4.3e-14 52.1 0.1 1.6e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_11 PF13086.1 CEP17812.1 - 0.24 10.9 0.0 0.24 10.9 0.0 3.9 4 1 0 4 4 4 0 AAA domain Arm PF00514.18 CEP17813.1 - 7.2e-14 51.0 7.8 1.8e-07 30.6 0.0 7.4 7 1 1 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEP17813.1 - 0.00022 21.4 0.3 0.54 10.5 0.0 4.8 4 2 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.15 CEP17813.1 - 0.002 16.5 2.1 4.4 5.5 0.0 4.2 4 1 1 5 5 5 2 Adaptin N terminal region HEAT_EZ PF13513.1 CEP17813.1 - 0.0077 16.6 0.2 0.11 13.0 0.0 3.1 3 0 0 3 3 3 1 HEAT-like repeat Ric8 PF10165.4 CEP17813.1 - 0.021 13.6 0.0 1.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn DUF3355 PF11835.3 CEP17813.1 - 0.042 13.6 0.2 0.29 10.9 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3355) EIID-AGA PF03613.9 CEP17813.1 - 0.14 11.0 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component YadA_stalk PF05662.9 CEP17813.1 - 0.29 10.9 1.9 5.6 6.8 0.3 2.8 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin Phage_int_SAM_4 PF13495.1 CEP17814.1 - 8.9e-05 22.7 0.1 0.00023 21.4 0.1 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 CEP17814.1 - 0.0015 18.6 0.2 0.0053 16.8 0.1 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF1604 PF07713.8 CEP17815.1 - 0.34 10.7 3.7 0.61 9.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) Mfp-3 PF04202.8 CEP17815.1 - 4.6 7.4 7.6 25 5.1 3.4 2.6 2 1 1 3 3 3 0 Foot protein 3 Cache_2 PF08269.6 CEP17816.1 - 0.023 14.6 9.9 0.19 11.7 0.3 3.2 3 0 0 3 3 3 0 Cache domain Cnd1 PF12717.2 CEP17816.1 - 0.07 12.9 2.4 0.12 12.2 1.6 1.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 IF-2B PF01008.12 CEP17817.1 - 2.3e-63 213.8 1.6 6e-63 212.4 1.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family TPP_enzyme_N PF02776.13 CEP17818.1 - 7.1e-32 110.2 0.0 1.2e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CEP17818.1 - 3.6e-21 75.3 0.0 6.1e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CEP17818.1 - 3.2e-17 62.5 0.1 2e-15 56.7 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.7 CEP17818.1 - 0.0035 16.8 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF362) PseudoU_synth_2 PF00849.17 CEP17819.1 - 1.7e-28 99.4 0.0 2.4e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 CEP17819.1 - 0.0031 16.8 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain RRM_1 PF00076.17 CEP17820.1 - 7e-23 80.0 0.0 2.2e-11 43.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP17820.1 - 1.4e-18 66.5 0.0 2.1e-10 40.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP17820.1 - 0.00012 21.8 0.0 0.083 12.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3825 PF12873.2 CEP17820.1 - 0.13 11.4 0.8 0.22 10.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Retinal PF15449.1 CEP17820.1 - 8.5 3.8 17.9 0.041 11.5 6.0 1.7 2 0 0 2 2 2 0 Retinal protein Ank_2 PF12796.2 CEP17821.1 - 1.6e-12 47.5 0.0 4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEP17821.1 - 6e-12 44.7 0.0 8.4e-07 28.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CEP17821.1 - 1.6e-11 44.0 0.5 5.1e-06 26.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.19 CEP17821.1 - 2e-11 43.7 0.1 2e-11 43.7 0.1 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.1 CEP17821.1 - 7.3e-08 31.9 0.1 0.00062 19.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CEP17821.1 - 1.8e-06 28.2 0.0 7.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Spt20 PF12090.3 CEP17821.1 - 0.0026 17.1 6.4 0.0026 17.1 4.4 3.6 4 0 0 4 4 4 2 Spt20 family AAA_23 PF13476.1 CEP17821.1 - 0.0082 16.4 18.3 0.072 13.4 4.1 3.1 3 0 0 3 3 3 2 AAA domain zf-DHHC PF01529.15 CEP17821.1 - 4.3 6.7 10.4 0.91 8.8 1.1 3.0 3 0 0 3 3 3 0 DHHC palmitoyltransferase SRP40_C PF05022.7 CEP17822.1 - 6.8e-28 96.9 2.3 2.2e-27 95.3 1.6 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.6 CEP17822.1 - 0.033 13.9 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 LisH zf-CCCH PF00642.19 CEP17823.1 - 6.8e-10 38.3 8.7 1.1e-05 24.9 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CEP17823.1 - 0.067 13.2 12.7 0.54 10.3 1.9 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF3488 PF11992.3 CEP17823.1 - 0.24 10.0 4.0 0.41 9.2 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) BAF1_ABF1 PF04684.8 CEP17823.1 - 0.27 10.0 22.6 0.55 9.0 15.7 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BTB_2 PF02214.17 CEP17824.1 - 4.9e-13 49.1 0.3 4.5e-06 26.7 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 CEP17824.1 - 0.005 16.8 0.1 0.84 9.6 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain RNase_H2_suC PF08615.6 CEP17824.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) BRCT PF00533.21 CEP17826.1 - 4.2e-10 39.6 0.0 1.2e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CEP17826.1 - 4.5e-10 39.2 0.0 1.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 CEP17826.1 - 0.00037 20.5 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III domain DUF3006 PF11213.3 CEP17826.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) WD40 PF00400.27 CEP17827.1 - 2.3e-14 52.6 1.5 0.0079 16.0 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1801 PF08818.6 CEP17827.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DU1801) PQQ_2 PF13360.1 CEP17827.1 - 0.047 13.1 0.1 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain Alginate_lyase PF05426.7 CEP17828.1 - 2.4e-16 59.9 0.1 3.7e-15 56.0 0.1 2.4 1 1 0 1 1 1 1 Alginate lyase HlyC PF02794.11 CEP17828.1 - 0.079 12.5 0.7 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 RTX toxin acyltransferase family Peptidase_M24 PF00557.19 CEP17829.1 - 3.7e-43 147.5 0.0 6.4e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CEP17829.1 - 1.9e-19 70.4 0.0 7.6e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain PP-binding PF00550.20 CEP17830.1 - 1.1e-13 51.2 0.2 1.5e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CEP17830.1 - 6.4e-07 29.3 1.1 1.1e-06 28.5 0.8 1.5 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 CEP17830.1 - 0.0043 17.1 0.2 0.0066 16.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.4 CEP17830.1 - 0.034 14.1 0.1 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S Peptidase_C54 PF03416.14 CEP17831.1 - 4.6e-80 268.7 0.0 2e-56 191.2 0.0 2.2 1 1 1 2 2 2 2 Peptidase family C54 tRNA_U5-meth_tr PF05958.6 CEP17832.1 - 4.7e-13 48.5 3.1 3e-12 45.8 0.3 3.2 2 2 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CEP17832.1 - 1.2e-12 47.6 0.1 4.9e-12 45.6 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP17832.1 - 8.4e-09 35.0 1.6 1.1e-08 34.7 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CEP17832.1 - 5.3e-08 33.4 0.0 3.5e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CEP17832.1 - 4.4e-07 29.4 0.0 1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 CEP17832.1 - 8.1e-07 29.0 0.0 2.1e-06 27.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CEP17832.1 - 4.5e-06 26.3 1.0 1.4e-05 24.7 0.1 2.1 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.1 CEP17832.1 - 0.0013 19.0 0.1 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CEP17832.1 - 0.0015 18.0 0.0 0.0049 16.4 0.0 1.8 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CEP17832.1 - 0.003 17.2 3.7 0.0062 16.2 0.2 2.6 3 0 0 3 3 3 1 Methyltransferase domain UPF0020 PF01170.13 CEP17832.1 - 0.0049 16.4 0.1 0.0049 16.4 0.1 2.1 3 0 0 3 3 3 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 CEP17832.1 - 0.0068 15.4 1.3 0.011 14.8 0.1 2.0 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 CEP17832.1 - 0.016 14.3 0.1 0.046 12.8 0.1 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPMT PF05724.6 CEP17832.1 - 0.032 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 CEP17832.1 - 0.049 13.0 0.3 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) FtsJ PF01728.14 CEP17832.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.7 CEP17832.1 - 0.087 11.6 0.2 0.59 8.9 0.0 2.3 2 1 1 3 3 3 0 DREV methyltransferase FLO_LFY PF01698.11 CEP17833.1 - 0.67 8.7 7.3 0.052 12.3 0.7 1.9 2 0 0 2 2 2 0 Floricaula / Leafy protein dCMP_cyt_deam_1 PF00383.17 CEP17834.1 - 1.1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 CEP17834.1 - 0.034 13.8 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase G-alpha PF00503.15 CEP17835.1 - 1.2e-126 422.5 6.6 1.3e-126 422.4 4.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP17835.1 - 1e-13 50.8 2.5 7.3e-10 38.3 0.1 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Miro PF08477.8 CEP17835.1 - 0.0012 19.3 2.1 1.9 8.9 0.0 3.0 3 1 0 3 3 3 2 Miro-like protein Gtr1_RagA PF04670.7 CEP17835.1 - 0.0013 17.9 3.6 0.023 13.8 0.1 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEP17835.1 - 0.0051 16.2 0.4 0.17 11.2 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP17835.1 - 0.014 15.3 0.2 4.1 7.3 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CEP17835.1 - 0.031 13.8 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_Rpb2_6 PF00562.23 CEP17836.1 - 6.4e-118 393.8 0.4 1.2e-117 392.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CEP17836.1 - 7.3e-59 198.1 1.3 1.5e-58 197.0 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CEP17836.1 - 9.8e-34 116.4 3.2 2.6e-33 115.0 2.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CEP17836.1 - 4.6e-31 106.8 2.6 7.4e-31 106.2 0.2 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 CEP17836.1 - 3.8e-22 77.8 0.2 1.3e-21 76.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 CEP17836.1 - 1.8e-21 75.6 3.0 5.9e-21 74.0 1.5 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 CEP17836.1 - 1.4e-13 50.5 0.3 3.2e-13 49.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF2051 PF09738.4 CEP17839.1 - 0.2 10.9 3.0 0.32 10.2 2.0 1.4 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Inhibitor_I9 PF05922.11 CEP17840.1 - 4.1e-08 33.6 0.3 5.6e-08 33.2 0.2 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cob_adeno_trans PF01923.13 CEP17841.1 - 1.3e-34 119.3 0.0 4.7e-34 117.5 0.0 1.9 2 0 0 2 2 2 1 Cobalamin adenosyltransferase Na_sulph_symp PF00939.14 CEP17841.1 - 4.7e-29 101.5 37.5 6.7e-29 101.0 26.0 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 CEP17841.1 - 3.7e-19 69.5 15.6 1.4e-13 51.3 0.1 3.4 3 1 0 3 3 3 2 SPX domain CitMHS PF03600.11 CEP17841.1 - 6.6e-14 51.2 40.2 2.5e-12 46.0 15.3 2.3 1 1 1 2 2 2 2 Citrate transporter 60KD_IMP PF02096.15 CEP17842.1 - 2.2e-29 102.5 6.9 3.6e-29 101.8 4.8 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Mac PF12464.3 CEP17842.1 - 1.5e-12 47.3 2.9 1.9e-12 46.9 0.1 2.4 3 0 0 3 3 3 1 Maltose acetyltransferase Hexapep PF00132.19 CEP17842.1 - 3.6e-11 42.0 20.2 1.1e-09 37.3 6.1 3.9 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CEP17842.1 - 2.3e-06 27.0 13.1 5.2e-05 22.7 5.4 2.7 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF3487 PF11990.3 CEP17842.1 - 0.084 12.2 1.1 0.45 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Pyr_redox_3 PF13738.1 CEP17843.1 - 9.3e-17 61.7 0.1 1.1e-15 58.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEP17843.1 - 9.4e-16 57.0 0.3 2.8e-15 55.5 0.1 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CEP17843.1 - 1.2e-10 40.8 1.1 1.1e-09 37.6 0.1 2.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEP17843.1 - 3e-10 39.9 0.1 8.7e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CEP17843.1 - 2.3e-05 24.1 0.4 0.00065 19.5 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEP17843.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEP17843.1 - 0.016 14.1 0.1 0.25 10.2 0.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP17843.1 - 0.14 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain EF-hand_1 PF00036.27 CEP17844.1 - 5.4e-28 94.1 9.4 2.4e-09 35.8 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 CEP17844.1 - 8.4e-24 81.8 9.3 4.5e-08 32.0 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CEP17844.1 - 3.5e-23 81.4 9.2 5e-13 48.9 1.8 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP17844.1 - 9.6e-22 74.8 5.6 3.3e-06 26.5 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CEP17844.1 - 4.5e-17 61.4 8.2 5.8e-09 35.4 1.3 3.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 CEP17844.1 - 1e-07 31.7 0.1 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CEP17844.1 - 2e-07 30.9 0.2 3.8e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEP17844.1 - 0.00022 20.9 0.9 0.024 14.3 0.3 2.5 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CEP17844.1 - 0.00037 20.1 0.2 0.033 13.7 0.0 2.7 1 1 2 3 3 3 1 Caleosin related protein ETF_QO PF05187.8 CEP17844.1 - 0.1 12.6 0.0 0.99 9.4 0.0 2.4 1 1 2 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase EF-hand_10 PF14788.1 CEP17844.1 - 1.6 8.4 6.0 11 5.7 0.2 2.9 2 2 1 3 3 3 0 EF hand Dockerin_1 PF00404.13 CEP17844.1 - 1.7 8.4 4.5 22 4.9 0.1 3.4 4 0 0 4 4 4 0 Dockerin type I repeat EF-hand_1 PF00036.27 CEP17845.1 - 3.6e-33 110.3 17.1 6.3e-09 34.4 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEP17845.1 - 7.4e-33 112.5 9.1 4e-17 62.1 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP17845.1 - 4.9e-26 88.2 9.0 6.7e-08 31.7 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CEP17845.1 - 1.6e-22 78.8 14.0 4.2e-12 45.4 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CEP17845.1 - 1.2e-19 68.6 12.6 1.3e-05 24.2 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CEP17845.1 - 3.6e-11 42.8 1.4 3.6e-07 30.0 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CEP17845.1 - 2.3e-05 24.3 1.7 0.063 13.3 0.1 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEP17845.1 - 3.7e-05 23.4 4.9 0.014 15.1 0.2 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 CEP17845.1 - 7.3e-05 22.6 0.6 0.00021 21.1 0.2 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DNA_pol_A_exo1 PF01612.15 CEP17845.1 - 0.00031 20.2 0.0 0.00085 18.8 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease UPF0154 PF03672.8 CEP17845.1 - 0.032 13.8 0.1 0.95 9.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Trigger_C PF05698.9 CEP17845.1 - 0.16 11.7 2.8 0.87 9.4 0.3 2.4 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus TBPIP PF07106.8 CEP17845.1 - 0.8 9.2 3.6 3.3 7.2 0.2 2.5 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3678 PF12435.3 CEP17845.1 - 1.9 8.1 6.6 2.8 7.5 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) KCl_Cotrans_1 PF03522.10 CEP17846.1 - 0.34 10.4 1.7 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) UCH PF00443.24 CEP17847.1 - 1.9e-39 135.4 0.3 2.7e-39 134.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP17847.1 - 1.4e-14 54.2 0.5 2.6e-14 53.3 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FAM176 PF14851.1 CEP17847.1 - 6.8 6.3 7.8 0.63 9.7 1.5 2.0 2 0 0 2 2 2 0 FAM176 family Ribosomal_L38e PF01781.13 CEP17848.1 - 3.6e-32 109.9 3.9 4e-32 109.7 2.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_90kDa PF04494.10 CEP17848.1 - 0.0043 17.1 0.4 0.0048 16.9 0.3 1.1 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Pox_A3L PF05288.6 CEP17848.1 - 0.078 12.7 0.3 0.93 9.2 0.1 2.1 1 1 0 2 2 2 0 Poxvirus A3L Protein CLTH PF10607.4 CEP17849.1 - 6.4e-16 58.3 0.6 1.2e-15 57.4 0.4 1.4 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Clathrin_H_link PF13838.1 CEP17849.1 - 0.0077 16.1 0.3 0.11 12.4 0.0 2.3 1 1 1 2 2 2 1 Clathrin-H-link MFS_1 PF07690.11 CEP17850.1 - 4.5e-31 107.8 81.9 2.5e-28 98.8 36.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP17850.1 - 0.03 12.7 39.5 0.0034 15.8 20.4 3.1 1 1 2 3 3 3 0 MFS/sugar transport protein Pkinase PF00069.20 CEP17851.1 - 1.4e-68 230.8 0.0 1.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17851.1 - 3.2e-33 114.9 0.0 4.5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP17851.1 - 2.9e-05 23.1 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP17851.1 - 0.028 13.4 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family eRF1_2 PF03464.10 CEP17852.1 - 1.6e-42 144.9 0.1 2.6e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CEP17852.1 - 9.2e-37 125.7 0.0 1.9e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CEP17852.1 - 2.9e-26 91.6 0.0 5.2e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Flavodoxin_NdrI PF07972.6 CEP17852.1 - 0.081 12.8 0.5 1.2 9.0 0.0 3.0 2 1 1 3 3 3 0 NrdI Flavodoxin like DUF3722 PF12519.3 CEP17853.1 - 6e-73 245.2 1.9 1.1e-71 241.1 1.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 CEP17853.1 - 6.7e-09 35.4 0.0 2.8e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic porin Cpn60_TCP1 PF00118.19 CEP17854.1 - 1e-144 482.8 18.0 1.2e-144 482.6 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 CEP17854.1 - 0.0031 16.7 0.3 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 Telomere recombination UQ_con PF00179.21 CEP17855.1 - 3.2e-21 75.2 0.1 4.7e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CEP17855.1 - 0.0035 17.2 0.1 0.0058 16.5 0.1 1.4 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 CEP17855.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 HSP70 PF00012.15 CEP17856.1 - 3.5e-07 28.5 0.0 1.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.15 CEP17856.1 - 0.08 12.2 0.1 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PPC PF04151.10 CEP17856.1 - 0.25 12.3 4.7 0.34 11.9 0.1 3.4 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain Ribosomal_L6 PF00347.18 CEP17857.1 - 9.2e-34 115.7 7.8 4.4e-19 68.7 2.1 2.0 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.7 CEP17857.1 - 0.16 12.1 1.0 1.1 9.4 0.1 2.6 3 1 0 3 3 3 0 YbbR-like protein Rhodanese PF00581.15 CEP17858.1 - 1.7e-10 41.2 0.0 4.2e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain BALF1 PF06861.6 CEP17859.1 - 0.13 11.6 0.2 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 BALF1 protein Ribosomal_L16 PF00252.13 CEP17860.1 - 5.6e-34 116.7 0.1 6.7e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.6 CEP17860.1 - 0.15 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Velvet PF11754.3 CEP17861.1 - 2.6e-50 170.8 0.0 4.3e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Velvet factor DUF1651 PF07864.6 CEP17861.1 - 0.06 13.4 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) DUF1803 PF08820.5 CEP17861.1 - 0.1 12.3 0.3 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) DUF2076 PF09849.4 CEP17862.1 - 0.0041 17.2 5.3 0.0047 17.0 3.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF3592 PF12158.3 CEP17862.1 - 0.15 11.8 1.3 0.2 11.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) DUF2415 PF10313.4 CEP17863.1 - 2.4e-15 55.9 0.6 5.9e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 CEP17863.1 - 5.1e-12 45.1 1.8 0.00013 21.7 0.6 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 CEP17863.1 - 0.044 13.5 0.0 7.6 6.3 0.0 2.6 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Lgl_C PF08596.5 CEP17863.1 - 0.061 11.7 0.0 0.17 10.2 0.0 1.7 1 1 1 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CEP17864.1 - 8.5e-41 136.4 19.2 2.9e-09 36.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CEP17864.1 - 0.0057 16.3 0.7 0.016 14.8 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CEP17864.1 - 0.0066 14.3 0.6 0.013 13.3 0.4 1.4 1 0 0 1 1 1 1 IKI3 family MFS_1 PF07690.11 CEP17865.1 - 1.7e-15 56.5 21.8 9e-15 54.2 15.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1056 PF06341.6 CEP17865.1 - 1.1 9.3 5.3 16 5.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) DUF2953 PF11167.3 CEP17865.1 - 3.6 7.5 5.5 0.59 10.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) Asp_protease_2 PF13650.1 CEP17866.1 - 0.00019 21.8 0.0 0.00046 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 CEP17866.1 - 0.0085 16.1 4.2 0.16 12.0 1.3 2.9 2 1 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.6 CEP17866.1 - 0.017 15.0 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP17866.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Haem_bd PF14376.1 CEP17867.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Haem-binding domain rve PF00665.21 CEP17868.1 - 2.5e-19 69.5 0.0 5.8e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CEP17868.1 - 0.074 12.5 0.0 0.22 11.0 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain rve PF00665.21 CEP17869.1 - 7.8e-18 64.7 0.0 2.1e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP17869.1 - 8.5e-15 54.6 0.0 2.2e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CEP17869.1 - 0.093 12.2 0.3 0.48 9.9 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain Methyltransf_11 PF08241.7 CEP17870.1 - 6.5e-09 36.1 0.0 2.6e-08 34.2 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP17870.1 - 3.6e-07 29.9 0.0 2.6e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CEP17870.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.1 CEP17870.1 - 3.9e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP17870.1 - 4.7e-05 22.6 0.0 0.00045 19.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CEP17870.1 - 7.8e-05 23.0 0.0 0.034 14.6 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP17870.1 - 0.012 15.9 0.0 0.056 13.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Lipase3_N PF03893.11 CEP17870.1 - 0.032 14.0 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipase 3 N-terminal region Methyltransf_4 PF02390.12 CEP17870.1 - 0.038 13.0 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_18 PF12847.2 CEP17870.1 - 0.038 14.5 0.0 0.13 12.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CEP17870.1 - 0.14 12.2 0.0 0.52 10.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DNA_pol_A_exo1 PF01612.15 CEP17871.1 - 5.6e-11 42.2 0.1 1.4e-09 37.6 0.1 2.6 2 1 0 2 2 2 1 3'-5' exonuclease zf-H2C2_2 PF13465.1 CEP17872.1 - 2.2e-17 62.3 17.8 3.6e-08 33.3 0.4 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP17872.1 - 2.8e-14 52.4 23.0 3e-05 24.0 2.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP17872.1 - 3.3e-09 36.4 21.4 0.0031 17.7 1.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP17872.1 - 2.3e-06 27.3 13.0 0.047 13.5 0.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Herpes_BLRF2 PF05812.7 CEP17872.1 - 0.019 14.7 6.8 0.78 9.5 0.9 2.5 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 CEP17872.1 - 0.027 14.4 3.5 0.81 9.6 0.6 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family GAGA PF09237.6 CEP17872.1 - 0.037 13.6 5.1 1.8 8.2 0.2 2.6 1 1 1 2 2 2 0 GAGA factor zf-H2C2_5 PF13909.1 CEP17872.1 - 0.044 14.0 21.5 0.12 12.6 2.3 3.6 4 0 0 4 4 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 CEP17872.1 - 0.12 12.5 18.4 0.32 11.1 1.0 4.0 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 CEP17872.1 - 0.14 11.8 0.1 0.14 11.8 0.0 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_4 PF07975.7 CEP17872.1 - 0.17 11.9 13.1 0.32 11.0 4.2 2.7 2 1 1 3 3 3 0 TFIIH C1-like domain bZIP_1 PF00170.16 CEP17872.1 - 0.2 11.6 2.3 0.44 10.5 1.2 1.9 1 1 1 2 2 2 0 bZIP transcription factor zf-CHY PF05495.7 CEP17872.1 - 0.41 10.8 10.4 1.3 9.2 6.4 2.2 1 1 1 2 2 2 0 CHY zinc finger zf-AN1 PF01428.11 CEP17872.1 - 0.47 10.3 17.0 0.24 11.3 0.7 3.4 1 1 2 3 3 3 0 AN1-like Zinc finger PHD PF00628.24 CEP17872.1 - 0.52 10.0 8.0 7.5 6.3 2.4 2.8 2 1 0 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 CEP17872.1 - 0.76 9.6 8.4 0.14 11.9 1.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain bZIP_2 PF07716.10 CEP17872.1 - 1.4 8.8 4.4 0.54 10.1 0.9 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Zn-ribbon_8 PF09723.5 CEP17872.1 - 3 7.8 9.9 21 5.1 2.0 3.2 1 1 2 3 3 3 0 Zinc ribbon domain Metallothio_Pro PF02069.11 CEP17872.1 - 6 6.7 7.6 0.16 11.8 0.5 1.9 3 0 0 3 3 1 0 Prokaryotic metallothionein DZR PF12773.2 CEP17872.1 - 6.2 6.7 8.0 1.8e+02 2.0 5.5 2.6 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.8 CEP17872.1 - 7.4 6.3 8.5 4 7.1 0.9 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like E1-E2_ATPase PF00122.15 CEP17873.1 - 2.9e-62 209.6 3.2 2.9e-62 209.6 2.2 3.6 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP17873.1 - 1.4e-46 158.3 8.4 1.4e-46 158.3 5.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP17873.1 - 2.6e-33 116.2 0.1 1.1e-32 114.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP17873.1 - 7.3e-21 73.9 0.0 1.5e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CEP17873.1 - 2.5e-18 65.3 0.1 5.6e-18 64.1 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEP17873.1 - 4.3e-17 62.9 0.0 1.1e-16 61.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP17873.1 - 1.7e-07 31.0 2.0 1.4e-06 28.1 1.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP17873.1 - 0.06 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Thymidylate_kin PF02223.12 CEP17874.1 - 1.8e-48 164.3 0.0 2.1e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 CEP17874.1 - 0.0072 16.2 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP17874.1 - 0.012 15.8 0.1 0.024 14.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 CEP17874.1 - 0.039 13.1 0.1 0.079 12.1 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PRK PF00485.13 CEP17874.1 - 0.043 13.3 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 CEP17874.1 - 0.053 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CEP17874.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CEP17874.1 - 0.077 13.3 0.1 0.2 11.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEP17874.1 - 0.088 12.7 0.1 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEP17874.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain DLIC PF05783.6 CEP17875.1 - 7.1e-60 203.0 19.7 9.2e-52 176.2 1.9 5.1 2 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 CEP17875.1 - 0.0003 20.8 0.0 0.00072 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CEP17875.1 - 0.0039 17.4 0.0 0.0095 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP17875.1 - 0.0046 17.1 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CEP17875.1 - 0.0097 16.2 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CEP17875.1 - 0.011 15.2 0.0 0.05 13.1 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.8 CEP17875.1 - 0.037 12.9 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 CEP17875.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CEP17875.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase MCM PF00493.18 CEP17875.1 - 0.061 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Sigma54_activ_2 PF14532.1 CEP17875.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 CEP17875.1 - 0.077 12.4 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 CEP17875.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 CEP17875.1 - 0.11 13.0 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein NTPase_1 PF03266.10 CEP17875.1 - 0.18 11.5 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 NTPase Arb2 PF09757.4 CEP17876.1 - 2.3e-14 53.2 0.3 3.7e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 Arb2 domain DUF2459 PF09601.5 CEP17876.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) KilA-N PF04383.8 CEP17877.1 - 0.00068 19.2 0.4 0.003 17.1 0.0 2.3 2 1 0 2 2 2 1 KilA-N domain Saccharop_dh PF03435.13 CEP17880.1 - 6.3e-89 298.6 0.0 9.3e-89 298.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 CEP17880.1 - 1.7e-30 105.8 0.1 1.1e-29 103.1 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CEP17880.1 - 7e-22 77.7 0.1 6.6e-21 74.6 0.0 2.6 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Trypsin PF00089.21 CEP17880.1 - 3.4e-11 43.1 0.0 6.3e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin Shikimate_DH PF01488.15 CEP17880.1 - 1.6e-05 25.0 0.3 5.6e-05 23.2 0.2 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 CEP17880.1 - 0.00032 20.9 0.1 0.00099 19.4 0.1 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CEP17880.1 - 0.0031 17.4 0.3 0.0063 16.4 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 CEP17880.1 - 0.0033 17.3 0.1 0.0072 16.2 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_7 PF13241.1 CEP17880.1 - 0.0074 16.5 0.2 0.023 14.9 0.2 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Trypsin_2 PF13365.1 CEP17880.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain NAD_binding_10 PF13460.1 CEP17880.1 - 0.13 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding YlqD PF11068.3 CEP17881.1 - 3.1 7.8 6.0 0.64 10.0 0.5 2.0 1 1 1 2 2 2 0 YlqD protein MT-A70 PF05063.9 CEP17883.1 - 5.1e-25 88.0 1.8 8.6e-25 87.3 1.2 1.3 1 0 0 1 1 1 1 MT-A70 Glucosamine_iso PF01182.15 CEP17884.1 - 9.8e-25 87.4 0.0 1.6e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DAHP_synth_1 PF00793.15 CEP17885.1 - 1.6e-94 315.5 0.1 1.9e-94 315.3 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF606 PF04657.8 CEP17886.1 - 8.3e-17 61.5 4.6 1.5e-16 60.7 3.2 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF606 DUF1632 PF07857.7 CEP17886.1 - 0.057 12.6 1.7 0.072 12.3 1.2 1.1 1 0 0 1 1 1 0 CEO family (DUF1632) Defensin_big PF14862.1 CEP17887.1 - 0.52 10.4 6.6 0.81 9.8 3.8 1.9 1 1 0 1 1 1 0 Big defensin GCR1_C PF12550.3 CEP17888.1 - 2e-15 56.4 0.3 8.8e-15 54.3 0.2 2.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Vps39_2 PF10367.4 CEP17889.1 - 4.2e-17 62.3 0.3 1.4e-16 60.6 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CEP17889.1 - 6.2e-16 58.3 2.1 5.8e-14 52.0 0.5 2.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 CEP17889.1 - 1.2e-13 51.0 0.0 2.1e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 CEP17889.1 - 0.0004 20.0 16.1 0.084 12.4 1.4 4.2 5 0 0 5 5 5 3 Region in Clathrin and VPS YafO_toxin PF13957.1 CEP17889.1 - 0.019 14.7 0.3 0.046 13.5 0.2 1.7 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system Oxidored_q6 PF01058.17 CEP17890.1 - 2.1e-22 79.1 0.1 3.2e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TrbC PF04956.8 CEP17891.1 - 0.087 12.8 2.6 0.25 11.3 1.7 1.8 1 1 0 1 1 1 0 TrbC/VIRB2 family Baculo_11_kDa PF06143.6 CEP17892.1 - 0.0028 16.9 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Baculovirus 11 kDa family DctQ PF04290.7 CEP17892.1 - 0.047 13.4 0.2 0.053 13.2 0.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2721 PF11026.3 CEP17892.1 - 0.11 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF997 PF06196.7 CEP17892.1 - 0.18 11.3 1.6 0.26 10.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) TMEM240 PF15207.1 CEP17892.1 - 0.26 10.8 1.2 0.35 10.4 0.8 1.3 1 1 0 1 1 1 0 TMEM240 family Ribosomal_S3_C PF00189.15 CEP17893.1 - 1e-13 51.3 0.1 1.9e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CEP17893.1 - 7.1e-13 47.9 0.1 1.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CEP17893.1 - 0.0068 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Metallophos PF00149.23 CEP17894.1 - 6.7e-41 139.8 0.4 8.5e-41 139.5 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RVT_1 PF00078.22 CEP17897.1 - 1.7e-11 43.8 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pil1 PF13805.1 CEP17899.1 - 1.3e-36 126.2 2.3 1.9e-36 125.5 1.6 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 BLOC1_2 PF10046.4 CEP17899.1 - 0.014 15.5 3.2 0.04 14.0 2.2 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_27 PF13514.1 CEP17899.1 - 0.017 12.8 3.5 0.028 12.1 2.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 CEP17899.1 - 0.049 14.0 5.2 1.8 9.0 1.9 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2205 PF10224.4 CEP17899.1 - 0.063 12.8 2.0 0.19 11.3 1.4 1.9 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Baculo_PEP_C PF04513.7 CEP17899.1 - 0.073 12.8 0.4 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus U1snRNP70_N PF12220.3 CEP17899.1 - 0.19 12.0 0.2 0.19 12.0 0.1 3.7 3 1 1 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ABC_tran_2 PF12848.2 CEP17899.1 - 2.4 8.0 8.2 0.38 10.6 1.9 2.4 2 0 0 2 2 2 0 ABC transporter T2SM PF04612.7 CEP17899.1 - 4.2 7.1 7.2 0.6 9.8 0.5 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M RAI16-like PF10257.4 CEP17900.1 - 1.4e-74 251.2 0.2 1.4e-74 251.2 0.1 1.7 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein p450 PF00067.17 CEP17903.1 - 1e-54 185.8 0.0 1.4e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAR1 PF03101.10 CEP17906.1 - 0.015 15.8 0.5 0.029 14.8 0.3 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain MFS_1 PF07690.11 CEP17907.1 - 1.8e-13 49.9 0.2 1.9e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CEP17907.1 - 0.0002 19.8 0.0 0.00023 19.6 0.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein DUF318 PF03773.8 CEP17907.1 - 0.038 12.9 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Predicted permease OATP PF03137.15 CEP17907.1 - 0.12 10.4 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF998 PF06197.8 CEP17907.1 - 3 7.0 8.9 0.088 12.1 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Fork_head PF00250.13 CEP17908.1 - 2e-34 117.4 0.2 2e-34 117.4 0.2 1.9 2 0 0 2 2 2 1 Fork head domain NIF PF03031.13 CEP17909.1 - 2.1e-44 150.9 0.0 3.3e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2077 PF09850.4 CEP17909.1 - 0.12 11.7 3.2 1.6 8.1 0.0 3.3 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2077) HAD_2 PF13419.1 CEP17909.1 - 0.12 12.5 0.2 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4199 PF13858.1 CEP17909.1 - 9.2 6.1 5.6 18 5.2 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Glucan_synthase PF02364.10 CEP17910.1 - 0 1314.0 0.0 0 1313.1 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CEP17910.1 - 1.6e-31 108.6 1.3 6e-31 106.7 0.1 2.5 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF629 PF04780.7 CEP17911.1 - 0.0017 16.9 4.7 0.045 12.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 CEP17911.1 - 0.02 15.2 0.6 0.02 15.2 0.4 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.2 CEP17911.1 - 0.04 14.1 0.9 0.04 14.1 0.6 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CEP17911.1 - 0.13 12.3 6.3 0.72 10.0 4.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CEP17911.1 - 0.15 11.8 0.1 0.15 11.8 0.0 2.7 3 0 0 3 3 3 0 BED zinc finger zf-AD PF07776.10 CEP17911.1 - 0.17 11.9 1.5 0.41 10.6 1.0 1.7 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-C2H2_jaz PF12171.3 CEP17911.1 - 0.32 11.1 0.4 0.32 11.1 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CEP17911.1 - 1.7 9.1 20.6 0.76 10.2 0.3 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger DUF155 PF02582.9 CEP17912.1 - 1.7e-57 194.1 0.3 3.2e-57 193.2 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 TraV PF09676.5 CEP17912.1 - 4.3 8.0 12.9 2.4 8.8 0.2 3.5 3 1 1 4 4 4 0 Type IV conjugative transfer system lipoprotein (TraV) Arf PF00025.16 CEP17913.1 - 1.7e-71 239.0 0.4 1.9e-71 238.9 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CEP17913.1 - 4.7e-12 45.2 1.3 1.4e-06 27.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CEP17913.1 - 1.1e-11 44.3 0.0 1.3e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CEP17913.1 - 6.6e-11 41.7 0.0 9e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEP17913.1 - 6e-10 38.6 0.0 7.6e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP17913.1 - 4.9e-09 36.7 0.0 6.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEP17913.1 - 4.6e-08 33.0 0.0 6.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP17913.1 - 6.2e-06 25.7 0.0 0.00025 20.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CEP17913.1 - 0.033 13.6 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CEP17913.1 - 0.038 13.6 0.2 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.13 CEP17913.1 - 0.11 11.7 0.1 0.25 10.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Aa_trans PF01490.13 CEP17914.1 - 2e-77 260.3 37.0 2.4e-77 260.1 25.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1201 PF06716.6 CEP17914.1 - 1.3 8.9 0.0 1.3 8.9 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1201) Myosin_tail_1 PF01576.14 CEP17915.1 - 0.00027 18.8 37.7 0.00027 18.8 26.1 1.9 1 1 0 1 1 1 1 Myosin tail HCMV_UL139 PF12507.3 CEP17915.1 - 0.012 15.8 5.7 0.012 15.8 4.0 3.1 1 1 2 3 3 3 0 Human Cytomegalovirus UL139 protein APG17 PF04108.7 CEP17915.1 - 0.03 13.1 25.4 0.059 12.1 8.5 2.3 1 1 1 2 2 2 0 Autophagy protein Apg17 HalX PF08663.5 CEP17915.1 - 0.049 13.6 0.2 0.049 13.6 0.1 4.7 3 2 2 5 5 5 0 HalX domain DASH_Hsk3 PF08227.6 CEP17915.1 - 0.068 13.3 4.7 0.36 11.0 0.6 2.7 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF3407 PF11887.3 CEP17915.1 - 0.2 10.9 1.6 0.57 9.4 0.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3407) AAA_13 PF13166.1 CEP17915.1 - 0.2 10.0 37.0 0.14 10.6 22.1 1.8 1 1 1 2 2 2 0 AAA domain DUF869 PF05911.6 CEP17915.1 - 0.58 8.3 38.5 0.094 10.9 18.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF4144 PF13642.1 CEP17915.1 - 0.98 9.7 8.2 0.26 11.6 2.4 2.4 1 1 1 2 2 2 0 protein structure with unknown function Syntaxin-6_N PF09177.6 CEP17915.1 - 1.3 9.4 30.0 4.4 7.7 1.7 3.8 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 CEP17915.1 - 2 8.2 44.4 0.24 11.2 5.4 3.1 1 1 2 3 3 3 0 Tropomyosin like TBPIP PF07106.8 CEP17915.1 - 2.1 7.8 38.6 0.6 9.6 3.3 3.2 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Flagellar_rod PF05149.7 CEP17915.1 - 3.4 6.7 35.2 0.67 9.0 4.4 3.2 1 1 2 3 3 3 0 Paraflagellar rod protein Reo_sigmaC PF04582.7 CEP17915.1 - 3.8 6.5 12.0 0.71 8.9 2.5 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIVA PF05103.8 CEP17915.1 - 7.8 6.5 38.9 1.3 9.0 10.5 3.9 1 1 3 4 4 4 0 DivIVA protein Filament PF00038.16 CEP17915.1 - 8.6 5.7 41.2 79 2.5 28.6 2.3 1 1 0 1 1 1 0 Intermediate filament protein G-patch PF01585.18 CEP17916.1 - 7.1e-15 54.5 1.4 2.1e-14 53.0 1.0 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CEP17916.1 - 4.4e-07 29.6 1.2 4.4e-07 29.6 0.8 3.8 2 1 1 3 3 3 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 CEP17916.1 - 0.0019 16.7 33.2 0.0023 16.4 23.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Paramyxo_ncap PF00973.14 CEP17916.1 - 0.033 12.9 16.5 0.04 12.6 11.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vfa1 PF08432.5 CEP17916.1 - 0.19 11.7 28.6 0.37 10.8 19.8 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BSMAP PF12280.3 CEP17916.1 - 0.21 11.4 6.3 0.29 11.0 4.3 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Rtf2 PF04641.7 CEP17916.1 - 0.28 10.3 29.5 0.47 9.6 20.5 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger SOBP PF15279.1 CEP17916.1 - 0.36 11.1 11.6 0.44 10.8 8.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 CEP17916.1 - 0.51 7.9 17.6 0.54 7.8 12.2 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 CEP17916.1 - 0.71 8.8 6.2 0.9 8.4 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.3 CEP17916.1 - 0.71 9.5 11.5 1.1 8.8 7.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region PLRV_ORF5 PF01690.12 CEP17916.1 - 1.8 7.6 19.1 2.1 7.3 13.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neur_chan_memb PF02932.11 CEP17916.1 - 1.9 8.3 9.9 2.7 7.8 6.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2413 PF10310.4 CEP17916.1 - 2.5 6.8 25.1 3.1 6.5 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1510 PF07423.6 CEP17916.1 - 2.5 7.3 33.4 4.4 6.6 23.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4551 PF15087.1 CEP17916.1 - 3.2 6.0 12.9 4.3 5.5 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.2 CEP17916.1 - 3.5 5.1 16.0 4.5 4.8 11.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 CEP17916.1 - 5.2 6.1 16.8 7.2 5.6 11.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 CEP17916.1 - 6 4.7 27.9 7.9 4.3 19.4 1.1 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.11 CEP17916.1 - 8.4 4.8 11.0 9.4 4.6 7.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PAP1 PF08601.5 CEP17917.1 - 8.2e-14 52.0 0.1 8.2e-14 52.0 0.1 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 CEP17917.1 - 1.3e-08 34.6 18.3 2.5e-07 30.5 12.7 2.5 1 1 0 1 1 1 1 bZIP transcription factor NYD-SP28_assoc PF14775.1 CEP17917.1 - 0.013 15.1 3.0 0.015 14.9 1.0 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain FlaC_arch PF05377.6 CEP17917.1 - 0.042 13.7 0.8 0.13 12.1 0.6 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PV-1 PF06637.6 CEP17917.1 - 0.051 12.1 3.4 0.07 11.6 2.3 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) bZIP_2 PF07716.10 CEP17917.1 - 0.085 12.6 22.3 27 4.6 15.5 2.5 1 1 0 1 1 1 0 Basic region leucine zipper HAUS-augmin3 PF14932.1 CEP17917.1 - 0.11 11.6 3.8 0.36 9.9 1.6 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Muted PF14942.1 CEP17917.1 - 0.15 11.9 5.2 0.32 10.8 3.6 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein bZIP_Maf PF03131.12 CEP17917.1 - 1.2 9.4 11.9 3.3 8.0 8.2 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Globin PF00042.17 CEP17918.1 - 1.2e-06 28.7 0.2 0.0041 17.4 0.0 2.7 3 0 0 3 3 3 2 Globin DER1 PF04511.10 CEP17919.1 - 1.1e-27 96.8 0.3 1.3e-27 96.5 0.2 1.0 1 0 0 1 1 1 1 Der1-like family SIR2 PF02146.12 CEP17921.1 - 5.9e-61 205.2 0.0 1e-60 204.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family UPF0121 PF03661.8 CEP17922.1 - 3.1e-14 52.7 7.2 5.2e-14 52.0 5.0 1.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Peptidase_M1 PF01433.15 CEP17923.1 - 4.6e-139 463.8 4.1 4.3e-87 292.7 0.1 2.1 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 CEP17923.1 - 8.6e-66 222.3 0.1 1.5e-65 221.6 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CEP17923.1 - 1.4e-18 67.1 0.4 3.4e-18 65.9 0.2 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Pro_isomerase PF00160.16 CEP17924.1 - 1.9e-49 167.8 0.4 5.1e-49 166.4 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CEP17924.1 - 8.1e-07 28.7 0.7 0.014 15.2 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Hemagglutinin PF00509.13 CEP17925.1 - 0.038 12.1 0.3 0.065 11.3 0.2 1.3 1 0 0 1 1 1 0 Haemagglutinin Pkinase PF00069.20 CEP17926.1 - 2.3e-75 253.1 0.0 3.3e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17926.1 - 1.9e-44 151.7 0.0 2.7e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP17926.1 - 2.3e-09 36.6 0.0 3.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP17926.1 - 0.00077 18.5 0.4 0.0013 17.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP17926.1 - 0.0024 17.6 0.1 0.0049 16.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Toxin_42 PF15522.1 CEP17926.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 42 DnaJ PF00226.26 CEP17927.1 - 5.5e-08 32.4 0.1 9.6e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CEP17927.1 - 0.0046 16.7 0.0 0.0046 16.7 0.0 1.2 1 1 0 1 1 1 1 Pam16 Peptidase_M24 PF00557.19 CEP17928.1 - 1.9e-28 99.4 0.5 2.4e-28 99.1 0.3 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Myb_DNA-bind_6 PF13921.1 CEP17929.1 - 0.001 19.0 0.3 0.0028 17.7 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain HLH PF00010.21 CEP17930.1 - 1e-12 47.5 0.3 3.8e-12 45.7 0.2 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain REC114-like PF15165.1 CEP17931.1 - 0.018 14.7 0.5 0.03 14.0 0.3 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Radical_SAM PF04055.16 CEP17932.1 - 1.1e-15 58.1 0.2 4.3e-15 56.2 0.1 2.0 1 1 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.11 CEP17932.1 - 5.8e-05 23.0 0.4 0.00071 19.5 0.2 2.7 2 1 0 2 2 2 1 HemN C-terminal domain Fer4_14 PF13394.1 CEP17932.1 - 0.024 14.6 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.1 CEP17932.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain ERO1 PF04137.10 CEP17933.1 - 6.4e-128 426.7 0.5 7.9e-128 426.4 0.4 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ResIII PF04851.10 CEP17934.1 - 1e-20 74.3 5.0 2.9e-20 72.8 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEP17934.1 - 7.2e-19 67.4 0.1 2e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEP17934.1 - 4.5e-16 58.8 0.0 1.3e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Actin PF00022.14 CEP17935.1 - 4.2e-162 539.0 0.0 4.8e-162 538.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CEP17935.1 - 0.081 13.3 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TAF PF02969.12 CEP17936.1 - 0.0057 16.5 0.8 0.0093 15.8 0.6 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) RRN3 PF05327.6 CEP17936.1 - 0.49 8.4 3.5 0.56 8.2 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HAND PF09110.6 CEP17936.1 - 1.8 9.0 10.4 3.3 8.1 1.2 2.1 1 1 1 2 2 2 0 HAND NAM-associated PF14303.1 CEP17936.1 - 4.9 7.4 12.6 6.7 7.0 8.8 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SPRY PF00622.23 CEP17937.1 - 3.2e-09 36.9 0.0 2.3e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 SPRY domain PHD PF00628.24 CEP17937.1 - 1e-07 31.5 8.9 2.1e-07 30.5 6.2 1.6 1 0 0 1 1 1 1 PHD-finger tRNA-synt_2 PF00152.15 CEP17938.1 - 5.4e-90 301.5 0.3 7e-90 301.1 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CEP17938.1 - 1.3e-12 47.4 0.0 2.3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CEP17938.1 - 1.1e-08 34.6 0.1 0.00069 18.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CEP17938.1 - 0.0093 15.5 0.4 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_60s PF00428.14 CEP17938.1 - 0.34 11.3 9.3 0.81 10.1 6.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PPR_2 PF13041.1 CEP17939.1 - 1.6e-13 50.4 1.4 0.0012 18.7 0.0 6.0 3 2 3 6 6 6 3 PPR repeat family PPR_3 PF13812.1 CEP17939.1 - 3.7e-08 33.0 2.7 0.24 11.7 0.0 7.4 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR PF01535.15 CEP17939.1 - 3.7e-08 32.7 2.0 0.011 15.6 0.1 6.5 8 0 0 8 8 7 1 PPR repeat MNE1 PF13762.1 CEP17939.1 - 3.4e-06 27.1 0.8 0.0037 17.3 0.0 3.5 3 1 1 4 4 4 1 Mitochondrial splicing apparatus component TPR_14 PF13428.1 CEP17939.1 - 0.00015 22.0 0.2 0.5 11.1 0.1 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat BTAD PF03704.12 CEP17939.1 - 0.00022 21.5 1.6 0.078 13.2 0.5 2.7 2 1 0 2 2 2 2 Bacterial transcriptional activator domain TPR_19 PF14559.1 CEP17939.1 - 0.00025 21.3 2.4 0.9 9.9 1.3 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 CEP17939.1 - 0.0023 17.3 0.0 0.88 9.1 0.0 4.0 4 0 0 4 4 4 1 PPR repeat TPR_12 PF13424.1 CEP17939.1 - 0.0089 15.9 1.2 0.93 9.4 0.4 3.9 3 1 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP17939.1 - 0.081 13.0 1.9 1 9.5 0.2 3.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CEP17939.1 - 0.19 12.4 0.8 4 8.2 0.1 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Septin PF00735.13 CEP17940.1 - 1.2e-105 352.5 0.0 1.2e-105 352.5 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CEP17940.1 - 0.00015 21.7 0.0 0.00038 20.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP17940.1 - 0.008 15.6 0.1 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RF-1 PF00472.15 CEP17940.1 - 0.021 14.6 1.5 0.05 13.3 0.4 2.1 2 0 0 2 2 2 0 RF-1 domain FMN_bind PF04205.9 CEP17940.1 - 0.063 13.4 0.4 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 FMN-binding domain Dynamin_N PF00350.18 CEP17940.1 - 0.21 11.3 2.8 0.92 9.3 0.1 2.7 2 1 1 3 3 3 0 Dynamin family OmpH PF03938.9 CEP17940.1 - 0.9 9.4 6.0 1.5 8.7 4.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ras PF00071.17 CEP17941.1 - 1.5e-56 190.2 0.2 2e-56 189.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP17941.1 - 2.6e-21 76.3 0.1 5.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP17941.1 - 2.6e-17 62.6 0.2 3.3e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP17941.1 - 6.4e-09 35.5 0.0 2.9e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP17941.1 - 8e-07 28.4 0.1 1e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEP17941.1 - 1.3e-06 27.7 0.1 1.9e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEP17941.1 - 2.1e-05 24.4 0.0 3.8e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CEP17941.1 - 0.025 14.7 0.0 0.81 9.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CEP17941.1 - 0.032 14.0 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 CEP17941.1 - 0.033 13.9 0.0 0.056 13.1 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 CEP17941.1 - 0.15 11.5 0.8 0.83 9.1 0.6 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Carn_acyltransf PF00755.15 CEP17942.1 - 8.3e-175 582.2 0.2 1.1e-174 581.8 0.2 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase YjcQ PF09639.5 CEP17942.1 - 0.073 13.1 0.1 0.25 11.4 0.1 1.9 1 0 0 1 1 1 0 YjcQ protein DUF563 PF04577.9 CEP17943.1 - 6.3e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Pox_F15 PF04596.7 CEP17943.1 - 0.0026 17.3 0.0 0.0071 15.9 0.0 1.7 2 0 0 2 2 2 1 Poxvirus protein F15 Ketoacyl-synt_2 PF13723.1 CEP17943.1 - 0.033 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Tmemb_cc2 PF10267.4 CEP17944.1 - 0.0043 15.6 1.1 0.0051 15.4 0.8 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF3530 PF12048.3 CEP17944.1 - 0.028 13.4 1.0 0.034 13.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) gpUL132 PF11359.3 CEP17944.1 - 0.38 10.0 6.8 0.59 9.4 4.7 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Presenilin PF01080.12 CEP17944.1 - 3.3 6.4 4.9 3.8 6.2 3.4 1.0 1 0 0 1 1 1 0 Presenilin Lsr2 PF11774.3 CEP17946.1 - 0.053 13.4 0.4 0.15 11.9 0.0 1.7 1 1 1 2 2 2 0 Lsr2 AIG1 PF04548.11 CEP17947.1 - 0.05 12.7 0.2 0.058 12.4 0.2 1.1 1 0 0 1 1 1 0 AIG1 family Cupin_8 PF13621.1 CEP17947.1 - 0.077 12.4 0.4 0.084 12.3 0.3 1.0 1 0 0 1 1 1 0 Cupin-like domain BCDHK_Adom3 PF10436.4 CEP17948.1 - 3e-66 221.9 0.1 4.6e-66 221.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CEP17948.1 - 1.4e-19 69.8 0.0 2.3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CEP17948.1 - 8.3e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gpi16 PF04113.9 CEP17949.1 - 3.3e-140 467.7 0.1 7.1e-138 460.0 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component NUDIX PF00293.23 CEP17950.1 - 0.0049 16.5 0.0 0.007 16.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain F-box-like PF12937.2 CEP17951.1 - 4.3e-09 35.9 0.0 1.3e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP17951.1 - 5.6e-05 22.6 0.0 0.0002 20.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain DUF2340 PF10209.4 CEP17951.1 - 0.48 10.5 4.5 6.5 6.9 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) LRR_4 PF12799.2 CEP17951.1 - 0.71 9.5 11.7 18 5.0 0.2 5.5 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) ING PF12998.2 CEP17952.1 - 9.6e-16 57.9 0.5 1.4e-15 57.4 0.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CEP17952.1 - 9.6e-09 34.8 8.1 1.5e-08 34.1 5.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CEP17952.1 - 0.048 13.7 0.9 0.094 12.8 0.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 CEP17952.1 - 0.081 12.2 3.1 0.16 11.3 2.1 1.5 1 0 0 1 1 1 0 PHD-finger WEMBL PF05701.6 CEP17952.1 - 0.12 10.8 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CTDII PF01556.13 CEP17953.1 - 9.9e-28 95.8 1.5 1.2e-19 69.9 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CEP17953.1 - 2.4e-26 91.2 3.8 2.4e-26 91.2 2.6 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CEP17953.1 - 1.4e-08 34.6 22.5 2.8e-08 33.6 15.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_CIII PF02085.11 CEP17953.1 - 0.84 9.7 10.8 0.14 12.2 3.4 2.4 2 0 0 2 2 2 0 Class III cytochrome C family Peptidase_S8 PF00082.17 CEP17954.1 - 4.1e-53 180.3 1.1 9.4e-53 179.1 0.8 1.6 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CEP17954.1 - 2.4e-26 91.3 0.7 5.6e-26 90.1 0.5 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Ten_N PF06484.7 CEP17954.1 - 0.051 12.6 3.7 0.09 11.8 0.1 2.2 2 0 0 2 2 2 0 Teneurin Intracellular Region BPL_N PF09825.4 CEP17955.1 - 0.15 10.8 6.3 0.18 10.5 4.4 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DNA_pol_A_exo1 PF01612.15 CEP17956.1 - 0.00013 21.5 0.0 0.00087 18.8 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease DUF2207 PF09972.4 CEP17957.1 - 0.053 12.0 0.1 0.057 12.0 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1440 PF07274.7 CEP17957.1 - 0.11 12.4 0.7 0.16 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) DUF3487 PF11990.3 CEP17957.1 - 0.14 11.5 1.0 0.21 10.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF1049 PF06305.6 CEP17957.1 - 0.16 11.4 1.9 0.26 10.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) WTF PF03303.8 CEP17957.1 - 1.1 8.5 5.2 0.86 8.9 2.8 1.4 1 1 0 1 1 1 0 WTF protein TPR_1 PF00515.23 CEP17958.1 - 1.2e-60 198.7 19.8 2.4e-08 33.2 0.0 10.2 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 CEP17958.1 - 3.2e-55 183.6 28.7 7.1e-12 44.7 0.4 6.9 2 2 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 CEP17958.1 - 8.7e-53 172.0 19.4 9e-06 25.2 0.0 9.6 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 CEP17958.1 - 4.9e-42 138.5 14.3 6.6e-06 25.5 0.5 9.5 9 1 1 10 10 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 CEP17958.1 - 2.4e-36 123.6 9.5 1.7e-09 38.0 0.2 6.7 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 CEP17958.1 - 1.2e-35 121.2 22.1 4.4e-09 36.1 0.1 7.0 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 CEP17958.1 - 5.9e-32 107.2 8.3 0.0012 19.2 0.0 9.3 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 CEP17958.1 - 3e-31 104.9 14.4 0.00019 21.3 0.0 10.7 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.1 CEP17958.1 - 2.9e-27 92.2 10.7 7.8e-05 22.1 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 CEP17958.1 - 1.2e-26 92.8 15.4 7.8e-06 26.1 0.2 7.0 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.1 CEP17958.1 - 3.6e-25 86.6 15.5 0.035 14.5 0.0 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_15 PF13429.1 CEP17958.1 - 5.2e-15 55.2 10.2 9.1e-05 21.6 0.5 5.1 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.1 CEP17958.1 - 5.3e-14 51.8 13.5 0.0065 16.3 0.3 6.5 4 3 2 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 CEP17958.1 - 1.9e-09 37.4 17.8 8.1e-05 22.6 2.2 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CEP17958.1 - 1.4e-05 24.8 15.1 0.044 13.7 0.0 7.4 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_21 PF09976.4 CEP17958.1 - 4.9e-05 23.3 12.0 0.12 12.3 0.5 5.0 2 2 2 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 CEP17958.1 - 0.00027 20.4 6.2 0.19 11.1 0.2 3.8 2 2 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.1 CEP17958.1 - 0.00036 19.7 16.2 0.16 11.1 0.9 4.7 1 1 2 4 4 4 4 Soluble NSF attachment protein, SNAP TPR_20 PF14561.1 CEP17958.1 - 0.01 15.9 8.6 2.9 8.0 0.0 5.0 5 1 1 6 6 4 0 Tetratricopeptide repeat Tcf25 PF04910.9 CEP17958.1 - 0.012 14.5 4.0 0.13 11.1 0.0 2.7 2 1 1 3 3 3 0 Transcriptional repressor TCF25 Rapsyn_N PF10579.4 CEP17958.1 - 0.036 13.8 1.0 3.7 7.4 0.0 3.6 2 1 3 5 5 5 0 Rapsyn N-terminal myristoylation and linker region ChAPs PF09295.5 CEP17958.1 - 0.092 11.4 1.6 16 4.0 0.0 2.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DNA_binding_1 PF01035.15 CEP17958.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF627 PF04781.7 CEP17958.1 - 0.19 11.3 1.5 29 4.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF627) MIT PF04212.13 CEP17958.1 - 0.23 11.3 25.7 2.8 7.8 1.3 6.3 7 1 0 7 7 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 CEP17958.1 - 0.9 9.4 21.2 9.2 6.1 0.4 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Ribosomal_L13 PF00572.13 CEP17959.1 - 4.6e-50 168.9 0.1 5.5e-50 168.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 OHCU_decarbox PF09349.5 CEP17960.1 - 4.5e-41 140.7 0.1 5.3e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase MFS_1 PF07690.11 CEP17962.1 - 0.0019 17.0 5.4 0.0028 16.4 3.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PTPS_related PF10131.4 CEP17962.1 - 0.042 12.0 0.5 0.058 11.5 0.2 1.3 1 1 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Syndecan PF01034.15 CEP17962.1 - 0.41 10.3 2.4 0.64 9.7 0.1 2.2 2 0 0 2 2 2 0 Syndecan domain MFS_1 PF07690.11 CEP17963.1 - 2e-11 43.2 2.1 2e-11 43.2 1.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP17963.1 - 0.00048 18.8 1.6 0.0005 18.7 1.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Ras PF00071.17 CEP17964.1 - 1.6e-57 193.4 0.3 2e-57 193.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP17964.1 - 2.2e-21 76.5 0.1 3.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP17964.1 - 2.9e-16 59.1 0.1 3.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP17964.1 - 1.8e-07 30.7 0.0 8.4e-07 28.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP17964.1 - 6.6e-06 25.4 0.1 8.1e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEP17964.1 - 1.8e-05 24.0 0.1 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEP17964.1 - 5.4e-05 23.1 0.0 0.00012 21.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CEP17964.1 - 0.0047 16.4 0.0 0.016 14.7 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 CEP17964.1 - 0.022 14.0 0.1 0.55 9.4 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 CEP17964.1 - 0.035 14.2 0.0 1.8 8.6 0.0 2.5 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.18 CEP17964.1 - 0.066 13.0 0.1 3 7.6 0.0 2.4 2 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 CEP17964.1 - 0.099 12.6 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MULE PF10551.4 CEP17965.1 - 1.9e-18 66.4 0.3 5.3e-18 64.9 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CEP17965.1 - 0.0062 15.1 0.1 0.011 14.2 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family DUF2733 PF10813.3 CEP17965.1 - 5.9 6.5 8.8 33 4.1 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2733) Rib_hydrolayse PF02267.12 CEP17966.1 - 3.4e-07 29.8 0.0 2.6e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosyl cyclase HLH PF00010.21 CEP17967.1 - 6e-10 38.6 1.4 6e-10 38.6 1.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3074 PF11274.3 CEP17967.1 - 0.27 10.8 3.9 0.39 10.3 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) DDE_3 PF13358.1 CEP17968.1 - 5.2e-18 65.1 0.1 7e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease U3_snoRNA_assoc PF08297.6 CEP17968.1 - 0.044 14.0 3.4 0.084 13.1 2.4 1.5 1 0 0 1 1 1 0 U3 snoRNA associated PGM_PMM_I PF02878.11 CEP17968.1 - 0.08 12.4 0.1 0.74 9.3 0.0 2.2 1 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Med2 PF11214.3 CEP17969.1 - 0.055 13.5 0.1 0.065 13.2 0.1 1.2 1 1 0 1 1 1 0 Mediator complex subunit 2 YjeF_N PF03853.10 CEP17970.1 - 2.5e-31 108.5 0.0 4.7e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 CEP17970.1 - 2e-05 25.0 6.0 2e-05 25.0 4.2 2.2 2 1 0 2 2 2 1 FDF domain LSM14 PF12701.2 CEP17970.1 - 0.0049 16.6 0.0 0.0049 16.6 0.0 2.9 3 1 0 3 3 3 1 Scd6-like Sm domain UPF0014 PF03649.8 CEP17971.1 - 2.3e-34 118.6 13.1 4e-34 117.9 9.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) DUF2457 PF10446.4 CEP17971.1 - 0.0009 18.0 17.6 0.0014 17.4 12.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 CEP17971.1 - 0.0039 15.7 14.5 0.0056 15.2 10.0 1.1 1 0 0 1 1 1 1 Daxx Family YL1 PF05764.8 CEP17971.1 - 0.021 14.4 7.6 0.034 13.7 5.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 CEP17971.1 - 0.04 11.8 18.0 0.059 11.2 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 CEP17971.1 - 0.086 12.2 14.7 0.14 11.5 10.2 1.2 1 0 0 1 1 1 0 Vta1 like SDA1 PF05285.7 CEP17971.1 - 2.9 7.0 20.6 4.4 6.4 14.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 CEP17971.1 - 3 5.7 13.8 4.3 5.2 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein HrpB7 PF09486.5 CEP17972.1 - 0.019 14.8 3.8 0.019 14.8 2.7 3.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 CEP17972.1 - 0.07 12.2 7.5 0.27 10.3 1.9 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3141 PF11339.3 CEP17972.1 - 0.25 9.6 5.4 0.058 11.7 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3141) DUF3216 PF11505.3 CEP17972.1 - 0.59 9.9 5.3 1.2 8.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3216) TMPIT PF07851.8 CEP17972.1 - 1.5 7.8 18.8 0.18 10.8 2.0 2.4 2 1 0 2 2 2 0 TMPIT-like protein DUF948 PF06103.6 CEP17972.1 - 2.1 8.2 19.6 0.15 11.9 0.3 4.3 1 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 CEP17972.1 - 6.7 5.6 32.0 0.67 8.9 13.3 2.6 2 1 0 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 CEP17972.1 - 8.3 4.9 35.1 0.32 9.6 5.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Pkinase PF00069.20 CEP17973.1 - 5.8e-29 101.0 0.0 1.2e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP17973.1 - 5.1e-05 22.4 0.0 0.0002 20.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PPR_2 PF13041.1 CEP17974.1 - 1.3e-32 111.4 7.8 6.9e-06 25.9 0.0 8.1 5 3 3 8 8 8 8 PPR repeat family PPR_3 PF13812.1 CEP17974.1 - 1.5e-23 81.0 6.8 0.0012 18.9 0.0 10.1 12 0 0 12 12 12 5 Pentatricopeptide repeat domain PPR PF01535.15 CEP17974.1 - 2.3e-14 52.2 11.3 0.0021 17.8 0.3 8.9 9 0 0 9 9 9 4 PPR repeat PPR_1 PF12854.2 CEP17974.1 - 1.5e-06 27.5 9.8 0.018 14.5 0.0 6.2 6 0 0 6 6 6 2 PPR repeat RPM2 PF08579.6 CEP17974.1 - 0.0014 18.7 4.5 3.6 7.7 0.0 4.1 3 1 0 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) DUF3366 PF11846.3 CEP17974.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) Nterm_IS4 PF13006.2 CEP17974.1 - 0.071 13.1 0.2 35 4.5 0.0 3.3 2 1 1 3 3 3 0 Insertion element 4 transposase N-terminal STE PF02200.11 CEP17975.1 - 3.4e-54 181.6 0.1 7.1e-54 180.6 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 CEP17975.1 - 4.2e-11 42.4 10.7 1.5e-05 25.0 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP17975.1 - 4.4e-10 39.1 6.7 0.00021 21.3 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP17975.1 - 2.5e-08 33.8 15.2 5.8e-08 32.6 1.6 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEP17975.1 - 0.00012 21.7 0.6 0.00012 21.7 0.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP17975.1 - 0.0011 19.0 0.6 0.0011 19.0 0.4 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Pox_Ag35 PF03286.9 CEP17975.1 - 0.0067 15.9 6.1 0.0067 15.9 4.3 2.3 3 0 0 3 3 3 1 Pox virus Ag35 surface protein FYDLN_acid PF09538.5 CEP17975.1 - 0.0071 16.9 11.4 0.0071 16.9 7.9 2.9 3 0 0 3 3 3 1 Protein of unknown function (FYDLN_acid) zf-met PF12874.2 CEP17975.1 - 0.023 14.8 5.8 0.15 12.3 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TFIIA PF03153.8 CEP17975.1 - 8.2 6.2 36.4 0.72 9.6 14.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fasciclin PF02469.17 CEP17976.1 - 4.4e-16 59.0 0.4 5.6e-16 58.7 0.3 1.1 1 0 0 1 1 1 1 Fasciclin domain SWIB PF02201.13 CEP17977.1 - 3.6e-25 87.4 0.1 1.3e-24 85.6 0.1 2.1 1 0 0 1 1 1 1 SWIB/MDM2 domain MOSP_C PF02722.10 CEP17977.1 - 0.039 13.5 0.5 0.097 12.2 0.0 1.9 2 0 0 2 2 2 0 Major Outer Sheath Protein C-terminal region PAT1 PF09770.4 CEP17977.1 - 1.8 6.7 65.7 0.02 13.1 39.9 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Vps51 PF08700.6 CEP17978.1 - 0.046 13.5 0.6 0.084 12.7 0.4 1.4 1 0 0 1 1 1 0 Vps51/Vps67 p450 PF00067.17 CEP17979.1 - 1.7e-76 257.6 0.0 2.2e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UCH PF00443.24 CEP17979.1 - 1.2e-23 83.6 0.0 2.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP17979.1 - 2.7e-11 43.4 0.0 4.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn-ribbon_8 PF09723.5 CEP17979.1 - 0.13 12.2 0.3 0.37 10.7 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Chitin_synth_2 PF03142.10 CEP17980.1 - 4.4e-242 804.1 1.8 7.1e-242 803.4 1.2 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEP17980.1 - 5.1e-159 530.5 5.9 6.5e-159 530.1 4.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 CEP17980.1 - 1.7e-18 66.1 0.0 1.1e-12 47.5 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 CEP17980.1 - 3.5e-18 66.0 0.9 3.5e-18 66.0 0.6 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP17980.1 - 3.6e-18 66.2 0.0 5.2e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEP17980.1 - 3.7e-06 26.7 0.0 0.00056 19.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP17980.1 - 7.8e-05 22.0 0.0 0.00033 19.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.1 CEP17980.1 - 0.014 15.5 0.0 0.05 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain WBS_methylT PF12589.3 CEP17981.1 - 5.9e-18 65.1 8.6 9.5e-18 64.4 6.0 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CEP17981.1 - 7.3e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP17981.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP17981.1 - 2.4e-06 27.2 0.0 3.6e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP17981.1 - 5.4e-06 26.7 0.0 1.2e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP17981.1 - 5.5e-06 26.9 0.0 8.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP17981.1 - 1.2e-05 25.6 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP17981.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 CEP17981.1 - 0.0052 16.8 0.0 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase PCMT PF01135.14 CEP17981.1 - 0.0053 16.3 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CEP17981.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ribosomal_S13 PF00416.17 CEP17982.1 - 2.9e-24 85.5 0.1 3.5e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CEP17982.1 - 0.0085 14.6 0.0 0.0092 14.5 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DEAD PF00270.24 CEP17983.1 - 1.1e-45 155.1 4.1 1.8e-45 154.4 0.5 2.9 3 1 1 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP17983.1 - 2.6e-27 94.5 0.2 8.8e-27 92.7 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CEP17983.1 - 1.4e-08 33.8 0.0 3.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CEP17983.1 - 0.0024 18.0 0.1 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 CEP17983.1 - 0.03 14.2 1.2 0.11 12.4 0.0 2.5 3 0 0 3 3 3 0 Helicase C-terminal domain Chitin_synth_2 PF03142.10 CEP17984.1 - 8.2e-81 271.9 2.1 8e-62 209.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 CEP17984.1 - 5.6e-07 29.5 0.0 0.001 18.9 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEP17984.1 - 0.0011 18.6 0.0 0.31 10.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP17984.1 - 0.0019 17.4 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 DEK_C PF08766.6 CEP17984.1 - 0.035 13.8 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 DEK C terminal domain Nucleoplasmin PF03066.10 CEP17984.1 - 3.1 7.2 5.8 7.2 6.1 3.4 1.9 2 0 0 2 2 2 0 Nucleoplasmin Cyclin PF08613.6 CEP17985.1 - 1.1e-16 61.5 0.7 2.2e-16 60.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CEP17985.1 - 0.0039 16.7 0.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain LUC7 PF03194.10 CEP17986.1 - 7.6e-57 192.7 18.3 1.1e-56 192.1 12.7 1.2 1 0 0 1 1 1 1 LUC7 N_terminus Ran-binding PF05508.6 CEP17986.1 - 0.12 11.2 2.9 0.53 9.1 0.5 2.2 2 0 0 2 2 2 0 RanGTP-binding protein V_ATPase_I PF01496.14 CEP17986.1 - 0.37 8.5 5.6 0.5 8.1 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CEP17986.1 - 1.1 8.8 16.7 0.056 13.0 7.1 1.9 2 0 0 2 2 2 0 IncA protein AKNA PF12443.3 CEP17986.1 - 8.3 6.4 10.3 0.27 11.2 0.4 2.9 1 1 2 3 3 3 0 AT-hook-containing transcription factor GPI-anchored PF10342.4 CEP17987.1 - 7.5e-09 35.9 0.8 1.7e-08 34.8 0.5 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_35 PF01301.14 CEP17988.1 - 9.3e-61 205.9 4.4 3.8e-43 148.0 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CEP17988.1 - 7.1e-11 42.3 3.1 1.8e-05 24.9 0.0 2.8 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain Cellulase PF00150.13 CEP17988.1 - 9.5e-05 21.7 0.0 0.00021 20.6 0.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BetaGal_dom2 PF10435.4 CEP17988.1 - 0.051 12.9 0.1 0.089 12.1 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 RasGEF PF00617.14 CEP17989.1 - 3.3e-43 147.6 0.2 5.5e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain Zn_clus PF00172.13 CEP17991.1 - 1.5e-10 40.7 24.6 7.8e-06 25.7 6.1 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP-utilisers_N PF05524.8 CEP17991.1 - 0.11 12.3 0.0 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF2031 PF09592.5 CEP17991.1 - 0.49 9.4 4.5 0.88 8.6 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) F-box-like PF12937.2 CEP17992.1 - 6.3e-06 25.8 1.7 1.4e-05 24.6 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP17992.1 - 3.2e-05 23.4 0.3 8.3e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain AdoMet_MTase PF07757.8 CEP17992.1 - 0.083 13.0 0.1 0.27 11.3 0.1 1.7 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Ank_2 PF12796.2 CEP17993.1 - 5.8e-80 263.7 16.7 1.3e-16 60.6 0.0 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 CEP17993.1 - 4.1e-79 256.6 15.4 1.8e-10 40.0 0.0 9.7 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 CEP17993.1 - 2.9e-59 191.0 10.5 7.4e-07 28.8 0.0 9.6 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 CEP17993.1 - 1.7e-55 184.4 9.3 1.9e-12 47.3 0.1 7.5 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP17993.1 - 1.1e-49 165.2 12.7 7.6e-09 35.5 0.2 8.7 3 3 6 9 9 9 9 Ankyrin repeats (many copies) NAD_binding_1 PF00175.16 CEP17994.1 - 2.1e-28 99.0 0.0 1.4e-27 96.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEP17994.1 - 1.3e-24 86.1 0.0 1.9e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CEP17994.1 - 2.2e-08 34.1 0.0 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CEP17994.1 - 0.0018 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Velvet PF11754.3 CEP17995.1 - 1.5e-51 174.8 1.2 1.5e-51 174.8 0.8 2.3 2 1 0 2 2 2 1 Velvet factor SBP_bac_5 PF00496.17 CEP17995.1 - 0.062 12.1 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle PBP1_TM PF14812.1 CEP17995.1 - 0.22 11.8 5.9 0.48 10.7 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SRF-TF PF00319.13 CEP17996.1 - 1.9e-22 78.2 0.2 2.9e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF605 PF04652.11 CEP17996.1 - 0.016 14.5 23.0 0.017 14.5 15.9 1.2 1 0 0 1 1 1 0 Vta1 like Med15 PF09606.5 CEP17996.1 - 0.73 7.9 40.7 0.92 7.6 28.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_LMP1 PF05297.6 CEP17996.1 - 0.9 8.3 4.5 1.6 7.5 3.1 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PAT1 PF09770.4 CEP17996.1 - 5.6 5.0 35.9 8.4 4.4 24.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CEP17996.1 - 7.9 4.0 25.1 12 3.4 17.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 CEP17996.1 - 8.1 6.2 33.5 12 5.6 23.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SH3_9 PF14604.1 CEP17997.1 - 2.6e-37 126.1 2.1 3.2e-14 52.2 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 CEP17997.1 - 3.6e-35 119.1 3.9 1.5e-12 46.7 0.1 3.7 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.12 CEP17997.1 - 1.3e-32 110.9 0.4 1.1e-10 40.7 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain tRNA-synt_2b PF00587.20 CEP17998.1 - 8.6e-46 155.6 0.1 1.3e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEP17998.1 - 9.3e-17 60.7 0.1 1.9e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.1 CEP17998.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Ank_2 PF12796.2 CEP17999.1 - 9.3e-129 420.1 33.9 3e-20 72.3 0.0 17.9 5 4 12 19 19 18 17 Ankyrin repeats (3 copies) Ank PF00023.25 CEP17999.1 - 2.2e-90 292.2 37.7 4e-06 26.3 0.0 29.9 29 2 0 29 29 29 19 Ankyrin repeat Ank_4 PF13637.1 CEP17999.1 - 2.7e-87 285.7 48.0 4.5e-09 36.5 0.1 23.8 17 6 10 27 27 27 18 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP17999.1 - 8.4e-66 216.5 43.3 2.3e-06 27.6 0.0 21.1 16 4 7 23 23 23 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP17999.1 - 6.2e-55 177.6 57.5 0.00049 20.0 0.0 29.8 33 0 0 33 33 33 14 Ankyrin repeat PARP PF00644.15 CEP17999.1 - 7.5e-43 146.3 0.0 1.9e-42 145.0 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.10 CEP17999.1 - 5.3e-16 58.3 0.0 1.7e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 WGR domain Bax1-I PF01027.15 CEP18000.1 - 1e-16 61.2 15.8 1e-16 61.2 10.9 1.8 1 1 1 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF2427 PF10348.4 CEP18000.1 - 0.75 9.4 4.2 11 5.6 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) Ribosomal_S7 PF00177.16 CEP18001.1 - 2.8e-39 134.0 0.3 3.3e-39 133.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e His_Phos_2 PF00328.17 CEP18002.1 - 5.1e-90 302.2 0.5 6.6e-90 301.9 0.4 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CEP18002.1 - 1.8e-08 34.0 0.0 3.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 CEP18002.1 - 0.022 14.8 0.0 0.075 13.1 0.0 2.0 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) ATP-grasp_3 PF02655.9 CEP18002.1 - 0.05 13.4 0.2 0.22 11.3 0.0 2.1 3 0 0 3 3 3 0 ATP-grasp domain SET PF00856.23 CEP18003.1 - 8.2e-12 45.7 0.3 1.7e-09 38.1 0.0 3.5 3 0 0 3 3 3 1 SET domain PHD PF00628.24 CEP18003.1 - 6e-09 35.4 10.2 1.2e-08 34.5 7.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEP18003.1 - 0.3 10.4 6.7 0.58 9.5 4.6 1.4 1 0 0 1 1 1 0 PHD-finger Acyl-CoA_dh_1 PF00441.19 CEP18004.1 - 5.3e-30 104.4 0.6 8.6e-30 103.8 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEP18004.1 - 1.8e-25 89.6 0.0 4.5e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CEP18004.1 - 1.3e-20 72.6 0.0 2.6e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CEP18004.1 - 1.8e-09 37.9 0.3 3.1e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 CEP18005.1 - 3.6e-25 88.5 0.0 7.5e-25 87.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18005.1 - 0.0015 17.6 0.0 0.019 14.0 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Init_tRNA_PT PF04179.7 CEP18006.1 - 2.3e-123 412.4 0.0 2.8e-123 412.1 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DSPc PF00782.15 CEP18006.1 - 7.9e-08 31.9 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TSKS PF15358.1 CEP18007.1 - 0.012 13.8 1.9 0.014 13.6 1.3 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate CcmD PF04995.9 CEP18007.1 - 1.7 8.4 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Med31 PF05669.7 CEP18008.1 - 8.1e-37 125.0 11.2 9.4e-37 124.8 7.8 1.0 1 0 0 1 1 1 1 SOH1 TypeIII_RM_meth PF12564.3 CEP18008.1 - 0.59 10.1 3.5 0.5 10.3 0.7 2.1 2 1 2 4 4 4 0 Type III restriction/modification enzyme methylation subunit DUF2347 PF09804.4 CEP18010.1 - 1.3e-69 234.6 0.3 2.1e-69 233.9 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 CEP18010.1 - 4e-09 36.1 0.2 8.9e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CEP18010.1 - 2.4e-08 32.8 0.5 0.0015 17.0 0.1 3.1 2 1 1 3 3 3 2 Transport protein Avl9 DUF4484 PF14831.1 CEP18010.1 - 3e-06 27.4 0.7 0.0031 17.6 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) DUF2373 PF10180.4 CEP18010.1 - 0.0017 17.8 0.0 0.44 10.1 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) Afi1 PF07792.7 CEP18010.1 - 0.0073 16.3 0.3 0.057 13.4 0.0 2.4 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Hist_deacetyl PF00850.14 CEP18011.1 - 2.2e-25 89.5 0.0 2.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CEP18011.1 - 0.0082 15.5 0.1 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain NAD_kinase PF01513.16 CEP18012.1 - 1.1e-60 204.8 0.0 6.8e-60 202.2 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase CDC27 PF09507.5 CEP18012.1 - 1.1e-46 159.9 30.5 1.1e-46 159.9 21.1 1.8 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 SUKH-3 PF14433.1 CEP18012.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 SUKH-3 immunity protein Fmp27 PF10344.4 CEP18013.1 - 0.012 13.3 1.3 0.011 13.4 0.9 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Mucin PF01456.12 CEP18013.1 - 0.26 11.0 21.3 0.34 10.6 14.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Med15 PF09606.5 CEP18013.1 - 0.45 8.6 4.3 0.58 8.2 3.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SSP160 PF06933.6 CEP18013.1 - 0.95 7.3 12.9 1.2 7.0 8.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PAP1 PF08601.5 CEP18013.1 - 5.5 6.5 7.0 6.8 6.2 4.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 H2TH PF06831.9 CEP18014.1 - 1.9e-20 72.3 0.0 6.2e-20 70.7 0.0 1.9 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain adh_short PF00106.20 CEP18014.1 - 3.2e-20 72.7 0.1 8.1e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase Fapy_DNA_glyco PF01149.19 CEP18014.1 - 6e-19 68.5 0.0 1.5e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain HLH PF00010.21 CEP18014.1 - 2.8e-15 55.7 1.9 9e-15 54.1 1.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain KR PF08659.5 CEP18014.1 - 1.1e-08 35.0 0.1 1.1e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 CEP18014.1 - 8.3e-07 29.0 0.0 0.00016 21.5 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_18 PF12847.2 CEP18014.1 - 0.00046 20.7 0.1 0.0062 17.0 0.1 2.5 1 1 1 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 CEP18014.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF3115 PF11312.3 CEP18015.1 - 7.1e-44 149.9 1.1 1.8e-43 148.5 0.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3115) CheR PF01739.13 CEP18015.1 - 0.00033 19.9 2.3 0.78 8.9 0.5 3.1 2 1 0 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 CEP18015.1 - 0.0056 17.0 0.3 0.24 11.7 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP18015.1 - 0.042 14.3 0.0 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Mpv17_PMP22 PF04117.7 CEP18016.1 - 3.2e-09 36.2 4.2 3.4e-09 36.2 1.8 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family Dispanin PF04505.7 CEP18016.1 - 0.066 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein EB PF01683.13 CEP18017.1 - 0.03 14.3 6.4 0.095 12.7 4.4 1.7 1 1 0 1 1 1 0 EB module Lipase_3 PF01764.20 CEP18018.1 - 1e-16 60.8 0.0 2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Nop14 PF04147.7 CEP18018.1 - 0.00062 17.8 10.1 0.00089 17.3 7.0 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 CEP18018.1 - 0.00082 17.9 11.8 0.0013 17.2 8.2 1.3 1 0 0 1 1 1 1 Daxx Family PGAP1 PF07819.8 CEP18018.1 - 0.0012 18.5 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CEP18018.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP18018.1 - 0.0025 17.5 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CEP18018.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold BUD22 PF09073.5 CEP18018.1 - 0.18 10.8 10.6 0.29 10.1 7.4 1.3 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.8 CEP18018.1 - 0.63 8.7 14.7 1.3 7.6 10.2 1.5 1 0 0 1 1 1 0 Paf1 Upf2 PF04050.9 CEP18018.1 - 1.6 8.5 17.5 1.4 8.6 10.8 1.9 2 0 0 2 2 2 0 Up-frameshift suppressor 2 CDC45 PF02724.9 CEP18018.1 - 1.9 6.3 13.5 3.3 5.6 9.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 CEP18018.1 - 3.1 7.6 10.6 6.5 6.5 7.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GLTP PF08718.6 CEP18019.1 - 4.2e-42 143.6 0.0 1.2e-41 142.1 0.0 1.8 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) HTH_28 PF13518.1 CEP18020.1 - 0.068 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-bind_6 PF13921.1 CEP18021.1 - 0.00058 19.9 0.1 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain FMN_dh PF01070.13 CEP18022.1 - 1.5e-114 382.6 0.1 1.4e-103 346.4 0.0 2.5 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Fork_head PF00250.13 CEP18022.1 - 2.2e-39 133.4 0.3 4.9e-39 132.2 0.2 1.6 1 0 0 1 1 1 1 Fork head domain Cyt-b5 PF00173.23 CEP18022.1 - 4.6e-26 90.4 0.0 8.8e-26 89.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.21 CEP18022.1 - 2.1e-11 43.7 0.0 4.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Glu_synthase PF01645.12 CEP18022.1 - 4.8e-09 35.6 0.0 1.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CEP18022.1 - 0.0016 17.4 0.0 0.004 16.0 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 CEP18022.1 - 0.013 14.6 0.0 0.031 13.4 0.0 1.7 1 0 0 1 1 1 0 Nitronate monooxygenase NIF PF03031.13 CEP18023.1 - 1.6e-33 115.6 0.8 4.6e-33 114.1 0.5 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Herpes_env PF01673.13 CEP18023.1 - 0.21 10.0 4.3 0.31 9.5 3.0 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF966 PF06136.8 CEP18023.1 - 1.6 8.0 13.5 2.6 7.3 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 CEP18023.1 - 4.4 5.4 15.6 5.5 5.1 10.8 1.2 1 0 0 1 1 1 0 Transmembrane protein PHD PF00628.24 CEP18024.1 - 3.2e-07 29.9 2.8 8.3e-07 28.6 1.9 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 CEP18024.1 - 0.11 12.2 1.5 0.15 11.8 0.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RAG2_PHD PF13341.1 CEP18024.1 - 0.2 11.6 1.9 0.82 9.6 0.2 2.3 2 0 0 2 2 2 0 RAG2 PHD domain PHD_2 PF13831.1 CEP18024.1 - 0.66 9.3 3.4 1.7 8.0 2.3 1.8 1 1 0 1 1 1 0 PHD-finger Abhydrolase_3 PF07859.8 CEP18025.1 - 8.7e-26 90.7 0.0 1.3e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEP18025.1 - 3.3e-17 62.2 0.1 5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 CEP18025.1 - 1.6e-05 24.2 0.1 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family SSV1_ORF_D-335 PF07935.6 CEP18025.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 ORF D-335-like protein FAR1 PF03101.10 CEP18026.1 - 1.3e-08 35.2 1.3 1.9e-08 34.7 0.9 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain Methyltransf_10 PF05971.7 CEP18027.1 - 1.5e-79 267.2 0.0 2.2e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 CEP18027.1 - 1.2e-05 25.3 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP18027.1 - 3.4e-05 23.2 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CEP18027.1 - 0.026 15.0 0.0 0.065 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 CEP18027.1 - 0.054 13.0 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.12 CEP18027.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 CEP18027.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TPR_19 PF14559.1 CEP18028.1 - 5.2e-11 42.7 2.1 4.3e-05 23.7 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEP18028.1 - 7.9e-10 38.2 2.3 0.0004 19.9 0.4 2.9 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 CEP18028.1 - 6.5e-09 35.6 0.4 0.036 14.6 0.1 4.4 2 2 3 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP18028.1 - 1.5e-08 34.4 4.9 0.00042 20.1 0.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CEP18028.1 - 6.7e-08 31.8 0.0 0.75 9.8 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 CEP18028.1 - 7.6e-08 32.3 2.1 0.6 10.6 0.0 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP18028.1 - 8.3e-07 29.5 0.0 0.031 14.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP18028.1 - 2.3e-06 27.6 0.8 0.071 13.2 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CEP18028.1 - 2.6e-05 23.6 0.3 0.53 9.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 CEP18028.1 - 5.1e-05 23.3 0.1 0.4 11.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEP18028.1 - 0.00014 21.3 1.8 1.6 8.7 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEP18028.1 - 0.00032 20.6 2.4 0.71 10.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP18028.1 - 0.0015 18.3 0.7 3.5 7.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 CEP18028.1 - 0.0057 16.0 0.7 0.089 12.1 0.0 2.1 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_9 PF13371.1 CEP18028.1 - 0.0057 16.4 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 CEP18028.1 - 0.014 15.3 0.8 0.83 9.7 0.0 3.5 4 0 0 4 4 3 0 PPR repeat TPR_8 PF13181.1 CEP18028.1 - 0.02 14.6 0.3 2.8 7.9 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.5 CEP18028.1 - 0.021 14.9 0.9 0.12 12.4 0.2 2.2 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) FMN_red PF03358.10 CEP18029.1 - 5.7e-13 48.6 0.0 8.1e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CEP18029.1 - 5.3e-06 26.4 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 CEP18029.1 - 9.6e-06 25.2 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CEP18030.1 - 5.1e-13 48.7 0.0 8.1e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CEP18030.1 - 1.1e-06 28.2 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 CEP18030.1 - 0.00046 20.1 0.1 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin RR_TM4-6 PF06459.7 CEP18030.1 - 4.3 7.1 7.2 5.9 6.6 5.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 bZIP_2 PF07716.10 CEP18031.1 - 3.4e-11 42.7 12.8 3.4e-11 42.7 8.9 2.3 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 CEP18031.1 - 0.00071 19.4 9.6 0.00071 19.4 6.7 1.8 2 0 0 2 2 2 1 bZIP transcription factor Phlebovirus_NSM PF07246.6 CEP18031.1 - 0.08 12.0 7.3 0.062 12.4 4.0 1.6 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Peptidase_M15_3 PF08291.6 CEP18032.1 - 0.013 15.3 3.6 0.91 9.3 0.1 3.1 2 1 1 3 3 3 0 Peptidase M15 Phi_1 PF04674.7 CEP18032.1 - 0.082 12.0 1.2 0.18 10.9 0.6 1.6 2 0 0 2 2 2 0 Phosphate-induced protein 1 conserved region peroxidase PF00141.18 CEP18033.1 - 4.3e-41 140.9 0.0 1e-40 139.6 0.0 1.6 2 0 0 2 2 2 1 Peroxidase PAT1 PF09770.4 CEP18035.1 - 7.4 4.6 29.9 9.8 4.2 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3808 PF10300.4 CEP18036.1 - 1.8e-94 316.9 12.6 3.9e-48 164.2 2.7 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_2 PF07719.12 CEP18036.1 - 1.9e-07 30.4 4.8 0.45 10.5 0.0 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEP18036.1 - 3.6e-06 26.5 6.0 0.0012 18.4 0.4 4.5 3 1 1 4 4 4 1 TPR repeat TPR_21 PF09976.4 CEP18036.1 - 0.0017 18.2 3.1 0.26 11.2 0.0 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat Sfi1_C PF10638.4 CEP18036.1 - 0.028 14.8 0.3 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Spindle body associated protein C-terminus TPR_1 PF00515.23 CEP18036.1 - 0.076 12.6 10.5 3.9 7.2 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2007 PF09413.5 CEP18036.1 - 0.084 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) TPR_16 PF13432.1 CEP18036.1 - 0.26 12.0 1.3 16 6.3 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP18036.1 - 6.9 6.7 12.8 25 4.9 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat PGK PF00162.14 CEP18037.1 - 1.8e-153 510.6 1.3 2.1e-153 510.4 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TGS PF02824.16 CEP18038.1 - 4.1e-23 80.9 0.1 7.8e-23 80.0 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CEP18038.1 - 2.1e-18 66.3 0.1 5.9e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP18038.1 - 2.1e-11 43.3 0.1 8.9e-11 41.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CEP18038.1 - 0.0017 17.8 0.3 3.7 6.9 0.0 3.4 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 CEP18038.1 - 0.0021 16.9 1.7 0.004 15.9 0.2 1.9 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 CEP18038.1 - 0.0032 17.2 0.4 0.78 9.5 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 CEP18038.1 - 0.0054 17.2 0.0 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 CEP18038.1 - 0.043 13.5 0.7 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Prenyltrans_2 PF13249.1 CEP18039.1 - 3.6e-31 107.8 0.2 4.3e-14 52.8 0.1 4.2 2 2 2 4 4 4 4 Prenyltransferase-like Prenyltrans PF00432.16 CEP18039.1 - 9.6e-26 89.0 4.6 6.6e-07 28.7 0.1 6.2 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CEP18039.1 - 2.3e-24 85.4 0.0 5.4e-15 55.3 0.3 5.5 2 2 1 5 5 5 5 Prenyltransferase-like Pec_lyase PF09492.5 CEP18039.1 - 4.8e-07 29.2 0.9 0.85 8.7 0.0 4.6 2 2 2 4 4 4 3 Pectic acid lyase X8 PF07983.8 CEP18039.1 - 0.00091 19.6 0.2 0.0022 18.4 0.2 1.6 1 0 0 1 1 1 1 X8 domain ALS_ss_C PF10369.4 CEP18040.1 - 1e-21 76.4 0.1 2.2e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 CEP18040.1 - 6e-12 44.7 0.1 1.3e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 CEP18040.1 - 4.6e-09 35.9 0.1 1.2e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 ACT domain Macro PF01661.16 CEP18041.1 - 9.5e-34 115.8 0.2 1.5e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Macro domain DUF3929 PF13066.1 CEP18041.1 - 0.14 11.9 0.2 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) AMP-binding PF00501.23 CEP18042.1 - 2.8e-47 161.0 0.0 5.4e-47 160.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CEP18042.1 - 2.5e-36 124.8 0.0 1.8e-35 122.0 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 CEP18042.1 - 1.2e-07 31.8 0.0 2.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CEP18042.1 - 0.00013 21.5 0.0 0.00056 19.4 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Phos_pyr_kin PF08543.7 CEP18043.1 - 3.5e-15 55.8 0.2 8.9e-15 54.5 0.1 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CEP18043.1 - 3.2e-11 42.9 1.3 1.3e-08 34.3 0.3 2.9 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Glutaredoxin PF00462.19 CEP18044.1 - 7.4e-14 51.4 0.0 1.9e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin Arrestin_C PF02752.17 CEP18044.1 - 6.7e-12 45.6 1.4 4.2e-08 33.3 0.2 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP18044.1 - 2.8e-11 43.4 0.0 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain GST_N_3 PF13417.1 CEP18044.1 - 0.0018 18.4 0.1 0.0065 16.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP18044.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 CEP18044.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) WD-3 PF09765.4 CEP18045.1 - 8.4e-26 90.9 1.0 8.1e-21 74.5 0.1 2.0 1 1 1 2 2 2 2 WD-repeat region Ras PF00071.17 CEP18046.1 - 3e-46 156.7 0.0 5.5e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP18046.1 - 5e-11 43.1 0.0 1.5e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Myb_DNA-binding PF00249.26 CEP18046.1 - 0.00014 21.7 0.1 0.00044 20.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP18046.1 - 0.0028 17.7 0.9 0.012 15.6 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain Gtr1_RagA PF04670.7 CEP18046.1 - 0.0036 16.4 0.0 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region EIN3 PF04873.8 CEP18046.1 - 0.0059 15.9 3.0 0.0059 15.9 2.1 1.6 2 0 0 2 2 2 1 Ethylene insensitive 3 DivIC PF04977.10 CEP18046.1 - 3.7 7.0 9.0 0.1 12.1 0.8 2.4 3 0 0 3 3 3 0 Septum formation initiator HSP9_HSP12 PF04119.7 CEP18047.1 - 0.0068 16.4 0.4 0.0095 15.9 0.3 1.3 1 0 0 1 1 1 1 Heat shock protein 9/12 RasGEF PF00617.14 CEP18049.1 - 5.8e-32 110.9 4.3 7e-17 61.7 0.4 2.8 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 CEP18049.1 - 7.1e-14 51.7 1.3 7.1e-14 51.7 0.9 3.5 3 0 0 3 3 3 1 RasGEF N-terminal motif zf-HC5HC2H_2 PF13832.1 CEP18050.1 - 1.9e-14 53.5 6.8 1.9e-14 53.5 4.7 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.1 CEP18050.1 - 1.1e-11 43.8 2.0 1.1e-11 43.8 1.4 2.0 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 CEP18050.1 - 1.1e-10 41.5 5.5 1.1e-10 41.5 3.8 3.0 2 2 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.24 CEP18050.1 - 3.7e-08 32.9 18.9 3.9e-08 32.8 4.7 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 CEP18050.1 - 0.00088 19.2 20.0 0.0059 16.5 6.2 3.1 2 1 0 2 2 2 2 RING-like domain Daxx PF03344.10 CEP18050.1 - 0.012 14.1 48.5 0.0028 16.2 31.1 1.7 1 1 1 2 2 2 0 Daxx Family SDA1 PF05285.7 CEP18050.1 - 0.33 10.1 41.0 0.19 10.9 25.1 2.3 2 0 0 2 2 2 0 SDA1 Vma12 PF11712.3 CEP18052.1 - 1.9e-20 73.0 0.5 3e-20 72.3 0.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase RST PF12174.3 CEP18053.1 - 0.041 13.6 0.3 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain DUF4047 PF13256.1 CEP18053.1 - 0.057 13.3 0.5 0.14 12.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) SR-25 PF10500.4 CEP18053.1 - 9.4 5.6 13.1 19 4.6 9.0 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4588 PF15251.1 CEP18054.1 - 3.4e-07 30.4 6.6 4.3e-07 30.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) DegT_DnrJ_EryC1 PF01041.12 CEP18054.1 - 0.078 12.0 1.3 0.33 9.9 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Arginase PF00491.16 CEP18055.1 - 3.5e-86 288.9 0.0 4.4e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 CEP18055.1 - 0.0043 17.2 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 UPF0489 domain Sel1 PF08238.7 CEP18056.1 - 2.6e-37 126.4 35.9 1.3e-07 32.0 0.0 12.3 13 0 0 13 13 13 9 Sel1 repeat TPR_7 PF13176.1 CEP18056.1 - 0.00031 20.2 2.3 0.98 9.3 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP18056.1 - 0.0087 16.4 10.0 29 5.4 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEP18056.1 - 0.018 15.6 20.2 1.8 9.3 0.6 6.1 4 2 1 5 5 5 0 Tetratricopeptide repeat Herpes_TK PF00693.13 CEP18056.1 - 0.096 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus DUF965 PF06135.7 CEP18056.1 - 0.26 11.3 2.4 11 6.1 0.1 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF965) TPR_14 PF13428.1 CEP18056.1 - 1.1 10.0 16.3 9 7.2 0.6 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 CEP18056.1 - 2.5 8.4 16.5 1.2 9.4 1.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP-synt_ab PF00006.20 CEP18057.1 - 1.1e-63 214.6 0.0 2.1e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEP18057.1 - 1.9e-24 86.3 1.0 3.2e-24 85.5 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEP18057.1 - 1.7e-18 66.6 4.0 2.1e-17 63.0 2.3 2.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain MobB PF03205.9 CEP18057.1 - 0.0024 17.5 0.1 0.96 9.1 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CEP18057.1 - 0.0036 17.0 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CEP18057.1 - 0.0059 16.2 0.1 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CEP18057.1 - 0.01 15.8 0.1 0.033 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 CEP18057.1 - 0.019 14.1 0.1 0.036 13.2 0.1 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 CEP18057.1 - 0.019 13.8 0.9 0.035 12.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 CEP18057.1 - 0.04 13.3 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CEP18057.1 - 0.041 14.0 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CEP18057.1 - 0.041 14.0 0.1 0.5 10.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CEP18057.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CEP18057.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Complex1_LYR PF05347.10 CEP18059.1 - 0.043 13.6 0.2 0.063 13.0 0.1 1.4 1 1 0 1 1 1 0 Complex 1 protein (LYR family) DUF349 PF03993.7 CEP18059.1 - 0.043 13.9 0.7 0.16 12.1 0.2 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Rhodanese PF00581.15 CEP18062.1 - 8e-13 48.7 0.0 8.9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain FH2 PF02181.18 CEP18063.1 - 1.9e-82 277.1 4.4 1.9e-82 277.1 3.1 3.1 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CEP18063.1 - 1e-25 90.1 14.0 2.2e-20 72.8 0.2 4.7 4 0 0 4 4 4 3 Diaphanous GTPase-binding Domain Ras PF00071.17 CEP18064.1 - 9.5e-33 112.8 1.8 1.7e-19 69.7 0.2 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CEP18064.1 - 1.1e-12 48.4 0.7 1e-09 38.8 0.5 2.5 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CEP18064.1 - 2.3e-06 26.9 0.8 7.2e-06 25.3 0.1 1.8 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CEP18064.1 - 6.9e-06 25.4 1.0 0.00062 19.0 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEP18064.1 - 0.00029 20.7 0.1 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CEP18064.1 - 0.0015 17.7 0.7 0.029 13.5 0.1 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 CEP18064.1 - 0.011 15.3 0.4 0.022 14.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CEP18064.1 - 0.024 14.7 0.1 0.17 12.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CEP18064.1 - 0.026 14.2 0.1 0.045 13.4 0.1 1.4 1 1 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 CEP18064.1 - 0.027 14.4 0.1 0.05 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CEP18064.1 - 0.048 12.8 0.4 0.14 11.3 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.13 CEP18064.1 - 0.05 12.6 0.1 0.077 12.0 0.1 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 CEP18064.1 - 0.087 13.1 0.3 0.15 12.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter Imm3 PF14425.1 CEP18064.1 - 0.089 12.7 0.1 0.18 11.7 0.1 1.4 1 1 0 1 1 1 0 Immunity protein Imm3 AAA_14 PF13173.1 CEP18064.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 CEP18064.1 - 0.24 10.8 1.3 7.5 5.9 0.1 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain MIP-T3 PF10243.4 CEP18065.1 - 0.3 9.4 30.7 0.64 8.4 21.2 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Fasciclin PF02469.17 CEP18066.1 - 3.2e-17 62.7 9.5 1e-11 44.9 0.6 2.6 2 1 0 2 2 2 2 Fasciclin domain Glyoxal_oxid_N PF07250.6 CEP18067.1 - 3.7e-66 222.6 0.0 5.3e-64 215.6 0.0 2.7 2 2 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CEP18067.1 - 2.2e-20 72.5 0.0 3.8e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 CEP18067.1 - 0.00027 20.9 0.2 3.2 8.0 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CEP18067.1 - 0.00056 19.6 0.1 1.1 9.0 0.0 3.4 4 0 0 4 4 4 2 Galactose oxidase, central domain MULE PF10551.4 CEP18068.1 - 0.00025 21.1 0.0 0.00075 19.6 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain RVT_1 PF00078.22 CEP18069.1 - 7.1e-19 68.0 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lactamase_B_4 PF13691.1 CEP18069.1 - 0.13 11.7 0.0 8.7 5.9 0.0 2.4 2 0 0 2 2 2 0 tRNase Z endonuclease GTP_EFTU PF00009.22 CEP18072.1 - 1.1e-33 116.2 0.0 4.4e-33 114.2 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CEP18072.1 - 7.9e-17 61.1 0.0 2.2e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CEP18072.1 - 1.7e-13 50.4 6.4 3.1e-09 36.7 0.0 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEP18072.1 - 4.1e-06 26.7 0.0 1.6e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CEP18072.1 - 0.0025 17.4 0.2 0.0089 15.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 CEP18072.1 - 0.0049 16.4 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CEP18072.1 - 0.0067 16.5 0.5 0.062 13.4 0.0 2.9 3 1 0 3 3 3 1 AAA domain ResIII PF04851.10 CEP18073.1 - 6.9e-26 91.2 0.9 2.2e-25 89.5 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEP18073.1 - 1.4e-14 53.9 1.1 3.7e-14 52.5 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP18073.1 - 3e-12 46.2 0.0 1.1e-11 44.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 CEP18073.1 - 1.7e-06 27.2 0.1 3.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 CEP18073.1 - 2.9e-06 26.3 0.5 4e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CEP18073.1 - 0.0024 17.9 0.1 0.027 14.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 CEP18073.1 - 0.013 14.4 0.2 0.022 13.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HCNGP PF07818.8 CEP18073.1 - 0.039 13.9 0.3 0.12 12.3 0.2 1.8 1 0 0 1 1 1 0 HCNGP-like protein Helicase_C_2 PF13307.1 CEP18073.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_10 PF12846.2 CEP18073.1 - 0.11 11.8 0.5 0.91 8.8 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain DDE_3 PF13358.1 CEP18074.1 - 8.6e-27 93.6 0.3 3.2e-26 91.8 0.0 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP18074.1 - 3.2e-06 27.2 0.0 5.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP18074.1 - 0.00017 21.1 0.0 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 CEP18074.1 - 0.00025 21.7 0.0 0.00084 20.0 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP18074.1 - 0.00032 20.6 0.2 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.7 CEP18074.1 - 0.0086 15.6 0.2 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1 PF01527.15 CEP18074.1 - 0.023 14.6 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_17 PF12728.2 CEP18074.1 - 0.11 12.8 0.0 3.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DRMBL PF07522.9 CEP18078.1 - 4.7e-31 107.0 0.0 1.1e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CEP18078.1 - 4.3e-08 32.9 0.0 1.2e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain HLH PF00010.21 CEP18079.1 - 7.2e-18 64.0 0.1 7.2e-18 64.0 0.0 3.0 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain GvpL_GvpF PF06386.6 CEP18079.1 - 1.1 8.8 10.4 2.3 7.7 0.2 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF TSA PF03249.8 CEP18079.1 - 1.2 7.5 15.4 1.7 7.0 10.7 1.2 1 0 0 1 1 1 0 Type specific antigen IncA PF04156.9 CEP18079.1 - 1.4 8.4 20.5 0.59 9.7 10.0 2.2 2 0 0 2 2 2 0 IncA protein GAS PF13851.1 CEP18079.1 - 2.7 7.1 22.7 0.048 12.8 10.4 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 CEP18079.1 - 4.1 6.2 22.1 0.85 8.5 9.8 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 CEP18080.1 - 2.3e-53 176.2 12.7 3.6e-11 42.5 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat PRP4 PF08799.6 CEP18080.1 - 3.8e-10 38.8 3.5 8e-10 37.8 2.4 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 CEP18080.1 - 0.00026 19.2 0.3 0.035 12.2 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 CEP18080.1 - 0.00042 19.5 0.1 0.28 10.2 0.0 3.1 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal RNA_pol_Rpb1_5 PF04998.12 CEP18081.1 - 1.9e-94 315.9 0.0 7.3e-93 310.8 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CEP18081.1 - 9.5e-62 207.8 0.1 2.8e-61 206.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CEP18081.1 - 1.3e-33 115.9 0.0 3.6e-33 114.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 CEP18081.1 - 3.3e-24 85.7 13.0 3.1e-22 79.2 0.1 4.0 4 1 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 CEP18081.1 - 1.9e-23 82.2 0.0 9.6e-23 79.9 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Mito_carr PF00153.22 CEP18082.1 - 8.6e-50 166.4 4.1 1.3e-17 63.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MULE PF10551.4 CEP18083.1 - 5.1e-14 52.2 0.2 1.3e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain LicD PF04991.8 CEP18083.1 - 0.048 13.7 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 LicD family zf-RVT PF13966.1 CEP18084.1 - 0.00017 21.8 0.2 0.00042 20.5 0.2 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase LSM PF01423.17 CEP18086.1 - 4.9e-14 51.6 0.2 6.3e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain RTC PF01137.16 CEP18087.1 - 9.7e-73 243.7 0.0 1.1e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CEP18087.1 - 3.2e-34 117.0 0.0 5.8e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RNA_pol_L_2 PF13656.1 CEP18088.1 - 3.7e-28 96.7 0.0 5.8e-28 96.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CEP18088.1 - 4.1e-10 38.6 0.0 6.8e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain F-box-like PF12937.2 CEP18091.1 - 1.2e-08 34.5 0.0 5.1e-08 32.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP18091.1 - 2.3e-05 23.9 1.0 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 1 F-box domain Phage-tail_1 PF09097.5 CEP18091.1 - 0.055 13.0 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Baseplate structural protein, domain 1 DEAD PF00270.24 CEP18092.1 - 1.6e-21 76.5 0.0 2.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP18092.1 - 1.4e-12 47.3 0.0 3.3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CEP18092.1 - 0.00019 20.5 0.0 0.00053 19.1 0.0 1.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 CEP18092.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit bZIP_1 PF00170.16 CEP18093.1 - 1.1e-10 41.2 8.0 1.1e-10 41.2 5.5 2.4 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.10 CEP18093.1 - 1.3e-09 37.7 3.1 1.3e-09 37.7 2.2 2.4 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 CEP18093.1 - 0.0004 20.6 3.1 0.0007 19.8 2.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Tropomyosin PF00261.15 CEP18093.1 - 0.0021 17.1 4.3 0.003 16.6 3.0 1.2 1 0 0 1 1 1 1 Tropomyosin Tup_N PF08581.5 CEP18093.1 - 0.27 11.4 3.3 3.6 7.8 2.3 2.1 1 1 0 1 1 1 0 Tup N-terminal NAM-associated PF14303.1 CEP18093.1 - 0.34 11.2 3.1 0.65 10.2 2.2 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PSRT PF07636.6 CEP18093.1 - 1.1 8.8 5.0 2.4 7.7 3.5 1.6 1 0 0 1 1 1 0 PSRT Ceramidase PF05875.7 CEP18094.1 - 1e-42 146.1 10.5 1.2e-42 145.8 7.3 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 CEP18094.1 - 0.024 14.2 1.3 0.079 12.6 0.9 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide HSF_DNA-bind PF00447.12 CEP18095.1 - 7.9e-36 122.3 3.0 7.9e-36 122.3 2.1 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding HlyD_2 PF12700.2 CEP18095.1 - 0.01 15.0 0.9 0.017 14.2 0.6 1.4 1 0 0 1 1 1 0 HlyD family secretion protein FliD_C PF07195.7 CEP18095.1 - 0.023 14.0 3.2 0.055 12.7 2.2 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ALMT PF11744.3 CEP18095.1 - 0.038 12.6 0.6 0.044 12.4 0.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Utp12 PF04003.7 CEP18095.1 - 0.07 13.0 2.4 0.14 12.0 1.6 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family Phage_GPO PF05929.6 CEP18095.1 - 0.11 11.7 4.4 0.23 10.7 3.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Cdc6_C PF09079.6 CEP18095.1 - 0.14 11.9 0.1 9.2 6.0 0.0 2.4 2 0 0 2 2 2 0 CDC6, C terminal Arch_fla_DE PF04659.8 CEP18096.1 - 0.099 12.4 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal flagella protein Herpes_ori_bp PF02399.10 CEP18097.1 - 0.00051 18.1 0.0 0.00061 17.8 0.0 1.0 1 0 0 1 1 1 1 Origin of replication binding protein AAA_22 PF13401.1 CEP18097.1 - 0.00061 19.9 0.0 0.0017 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CEP18097.1 - 0.0016 18.3 0.2 0.0055 16.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CEP18097.1 - 0.0037 16.8 0.0 0.0043 16.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 CEP18097.1 - 0.01 15.6 0.6 0.31 10.8 0.4 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 CEP18097.1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CEP18097.1 - 0.013 15.6 0.0 0.034 14.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CEP18097.1 - 0.043 13.5 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF3050 PF11251.3 CEP18099.1 - 0.049 12.8 0.0 0.058 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Plant_tran PF04827.9 CEP18099.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein HTH_32 PF13565.1 CEP18100.1 - 0.035 14.8 0.0 0.17 12.7 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DAGAT PF03982.8 CEP18101.1 - 1.1e-97 326.3 0.0 1.3e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase YTV PF07639.6 CEP18101.1 - 0.037 13.7 0.3 0.079 12.6 0.2 1.5 1 0 0 1 1 1 0 YTV Homeobox PF00046.24 CEP18102.1 - 2.2e-16 59.1 1.8 4.7e-16 58.1 1.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP18102.1 - 0.002 17.7 0.2 0.007 16.0 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain RRM_2 PF04059.7 CEP18103.1 - 2.5e-26 91.4 3.9 3.9e-26 90.8 1.9 2.0 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 CEP18103.1 - 0.05 13.2 0.6 0.88 9.2 0.1 3.1 3 1 1 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 CEP18104.1 - 1.9e-26 92.5 0.4 3.5e-26 91.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP18104.1 - 5.2e-10 39.0 9.6 1.2e-09 37.9 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI3_PI4_kinase PF00454.22 CEP18105.1 - 5.5e-29 101.2 1.1 8.9e-28 97.3 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAM60A PF15396.1 CEP18105.1 - 3.8 7.1 13.7 4 7.1 2.8 2.5 2 0 0 2 2 2 0 Protein Family FAM60A SprA-related PF12118.3 CEP18105.1 - 6.8 5.9 28.5 0.21 10.8 7.8 2.3 2 0 0 2 2 2 0 SprA-related family DDE_3 PF13358.1 CEP18106.1 - 1.7e-10 40.8 0.1 2.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP18108.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP18108.1 - 0.028 14.0 0.1 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 CEP18108.1 - 0.037 13.9 0.1 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Transposase Nic96 PF04097.9 CEP18109.1 - 9.1e-137 456.7 16.2 1.3e-136 456.2 11.2 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Noc2 PF03715.8 CEP18110.1 - 1e-81 274.0 0.1 1.7e-81 273.3 0.1 1.3 1 0 0 1 1 1 1 Noc2p family IPK PF03770.11 CEP18110.1 - 0.041 13.5 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Inositol polyphosphate kinase Methyltransf_24 PF13578.1 CEP18110.1 - 0.047 14.5 0.0 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-DHHC PF01529.15 CEP18111.1 - 1.4e-40 138.5 7.2 1.4e-40 138.5 5.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase QueC PF06508.8 CEP18111.1 - 0.16 11.1 4.2 0.27 10.4 2.9 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF3816 PF12822.2 CEP18111.1 - 5.2 6.9 12.7 0.23 11.3 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) RVT_1 PF00078.22 CEP18112.1 - 8.1e-27 93.9 0.5 2.7e-26 92.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP18112.1 - 1.1e-08 34.6 0.3 3.7e-08 33.0 0.2 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP18112.1 - 1.7e-05 24.8 0.3 3.5e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CEP18112.1 - 0.00065 19.9 1.1 0.0023 18.1 0.8 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 CEP18113.1 - 4.1e-06 26.4 18.7 4.4e-05 23.1 3.4 2.4 2 0 0 2 2 2 2 Zinc knuckle DUF4559 PF15112.1 CEP18113.1 - 0.61 9.1 8.9 0.29 10.2 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) SNF2_N PF00176.18 CEP18114.1 - 2.7e-64 216.8 0.0 5.4e-64 215.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP18114.1 - 2.7e-13 49.5 0.0 8.4e-13 47.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Rad54_N PF08658.5 CEP18114.1 - 2.1e-06 27.6 0.6 2.1e-06 27.6 0.4 5.0 1 1 2 3 3 3 1 Rad54 N terminal AAA_22 PF13401.1 CEP18114.1 - 0.057 13.5 0.6 0.32 11.1 0.1 2.5 3 1 0 3 3 3 0 AAA domain gag_pre-integrs PF13976.1 CEP18114.1 - 0.35 10.5 2.5 0.27 10.8 0.2 2.1 2 0 0 2 2 2 0 GAG-pre-integrase domain DUF1838 PF08894.6 CEP18115.1 - 1.6e-61 207.6 0.2 2.5e-61 206.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) CUE PF02845.11 CEP18115.1 - 4.5e-12 45.2 0.0 1.1e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 CUE domain HAD PF12710.2 CEP18116.1 - 2e-20 73.7 0.7 4.2e-20 72.7 0.5 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEP18116.1 - 1.2e-16 60.4 0.0 2.1e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEP18116.1 - 1.3e-14 55.1 0.2 2.2e-13 51.1 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP18116.1 - 3.1e-11 43.0 0.0 9.3e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEP18116.1 - 0.00036 20.1 0.3 0.0014 18.2 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP18116.1 - 0.041 14.1 0.1 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Glucosamine_iso PF01182.15 CEP18117.1 - 4.9e-24 85.1 0.0 7.5e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_1 PF00349.16 CEP18118.1 - 4.8e-49 166.4 0.0 7.2e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CEP18118.1 - 6.2e-45 153.2 0.0 8.1e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase SAD_SRA PF02182.12 CEP18119.1 - 4.3e-30 104.0 0.0 1.1e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 SAD/SRA domain Exo_endo_phos PF03372.18 CEP18119.1 - 5.5e-17 62.5 0.1 1.2e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C3HC4_3 PF13920.1 CEP18119.1 - 0.00011 21.7 12.2 0.00011 21.7 8.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEP18119.1 - 0.00023 20.9 8.5 0.00023 20.9 5.9 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CEP18119.1 - 0.0023 17.8 12.4 0.0023 17.8 8.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP18119.1 - 0.0033 17.1 13.6 0.0033 17.1 9.4 2.9 2 1 0 2 2 2 1 zinc-RING finger domain ubiquitin PF00240.18 CEP18119.1 - 0.0034 16.7 0.6 0.031 13.6 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin family Sugar_tr PF00083.19 CEP18120.1 - 3e-99 332.6 32.3 2.3e-52 178.0 5.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP18120.1 - 4e-26 91.5 62.8 7.1e-25 87.4 21.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP18120.1 - 0.53 8.6 40.8 0.039 12.3 10.8 3.6 2 2 2 4 4 4 0 MFS/sugar transport protein zf-C2H2 PF00096.21 CEP18121.1 - 3e-10 39.8 22.4 2.3e-05 24.4 0.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP18121.1 - 3e-09 36.6 21.7 3.9e-06 26.8 1.6 4.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP18121.1 - 2.4e-06 27.4 19.1 0.00027 21.0 0.1 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-TRAF PF02176.13 CEP18121.1 - 0.00047 20.4 2.6 0.00071 19.8 1.0 2.0 1 1 0 1 1 1 1 TRAF-type zinc finger zf-C2H2_6 PF13912.1 CEP18121.1 - 0.0019 18.0 0.3 0.49 10.3 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DDE_3 PF13358.1 CEP18122.1 - 1.2e-17 63.9 0.3 1.9e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP18122.1 - 1.7e-13 50.4 0.3 3.3e-13 49.4 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 CEP18122.1 - 0.0028 18.4 0.1 0.0081 16.9 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain LacI PF00356.16 CEP18122.1 - 0.0041 16.6 0.1 0.011 15.2 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_29 PF13551.1 CEP18122.1 - 0.0065 16.6 0.1 0.014 15.5 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix PigN PF04987.9 CEP18123.1 - 9.3e-131 436.4 41.7 1.3e-130 435.9 28.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CEP18123.1 - 4.9e-10 39.2 0.0 2.5e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CEP18123.1 - 3.2e-05 23.2 0.0 4.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4034 PF13226.1 CEP18123.1 - 0.15 11.1 0.1 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) Nop14 PF04147.7 CEP18124.1 - 0.57 8.0 6.4 1.2 7.0 4.5 1.4 1 0 0 1 1 1 0 Nop14-like family Cys_Met_Meta_PP PF01053.15 CEP18125.1 - 5.1e-141 469.4 0.0 1.2e-90 303.6 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CEP18125.1 - 1.4e-10 40.7 0.0 2.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CEP18125.1 - 3.2e-09 36.3 0.0 5.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CEP18125.1 - 1.9e-07 30.1 0.1 2.9e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.8 CEP18125.1 - 1.3e-06 27.4 0.0 3e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.16 CEP18125.1 - 2.8e-06 26.7 0.0 1.1e-05 24.6 0.0 1.9 2 1 0 2 2 2 1 Beta-eliminating lyase GDC-P PF02347.11 CEP18125.1 - 0.0016 17.2 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 CEP18125.1 - 0.0023 16.3 0.0 0.0037 15.6 0.0 1.4 1 0 0 1 1 1 1 Methionine gamma-lyase Rep_fac-A_C PF08646.5 CEP18126.1 - 1.3e-49 167.6 12.2 3e-47 160.0 4.3 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 CEP18126.1 - 8.5e-21 73.6 0.8 2.8e-20 71.9 0.6 1.9 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 CEP18126.1 - 3.1e-14 52.5 0.2 2.4e-10 40.0 0.0 3.6 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 CEP18126.1 - 0.00081 19.4 0.3 0.00081 19.4 0.2 2.3 3 0 0 3 3 3 1 Domain of unknown function DUF223 zinc-ribbons_6 PF07191.7 CEP18126.1 - 0.0078 15.9 1.4 0.024 14.3 1.0 1.8 1 0 0 1 1 1 1 zinc-ribbons Ribosomal_L37ae PF01780.14 CEP18126.1 - 0.047 13.5 1.1 0.19 11.6 0.8 2.0 1 0 0 1 1 1 0 Ribosomal L37ae protein family C1_1 PF00130.17 CEP18126.1 - 0.55 9.9 4.0 1.1 8.9 2.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ATG22 PF11700.3 CEP18127.1 - 1.8e-99 333.4 30.5 2e-99 333.2 21.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CEP18127.1 - 3.8e-16 58.7 34.4 1.7e-06 27.0 9.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 CEP18127.1 - 0.00034 20.3 3.5 0.00034 20.3 2.4 3.1 3 0 0 3 3 3 1 MFS_1 like family Ion_trans PF00520.26 CEP18128.1 - 0.18 11.0 3.4 0.22 10.7 2.4 1.1 1 0 0 1 1 1 0 Ion transport protein DUF822 PF05687.8 CEP18129.1 - 2 8.7 5.2 0.75 10.1 1.8 1.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) Asp PF00026.18 CEP18130.1 - 8.9e-51 173.0 1.1 2.8e-50 171.3 0.8 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEP18130.1 - 3.5e-09 36.8 1.6 5.5e-09 36.1 0.7 1.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEP18130.1 - 0.00017 21.1 0.0 0.00062 19.3 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal IFRD PF05004.8 CEP18131.1 - 1.4e-39 135.9 2.4 1.4e-39 135.9 1.7 1.6 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) DUF4455 PF14643.1 CEP18131.1 - 0.013 14.1 0.3 0.019 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF904 PF06005.7 CEP18131.1 - 0.17 12.2 3.9 0.2 11.9 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Xan_ur_permease PF00860.15 CEP18132.1 - 1.6e-58 198.1 27.9 2.6e-57 194.0 19.4 2.0 1 1 0 1 1 1 1 Permease family MPC PF03650.8 CEP18132.1 - 0.027 14.4 1.1 0.093 12.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0041) Glyco_hydro_18 PF00704.23 CEP18133.1 - 9.8e-94 314.6 0.8 1.1e-93 314.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ATP_sub_h PF10775.4 CEP18134.1 - 6.6e-20 70.6 1.9 8.2e-20 70.3 1.3 1.1 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 CEP18134.1 - 0.0027 17.5 0.1 0.0037 17.1 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 Oxidored_FMN PF00724.15 CEP18135.1 - 1.5e-79 267.4 0.0 1.8e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 CEP18135.1 - 0.025 13.3 0.1 0.057 12.2 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) ArfGap PF01412.13 CEP18136.1 - 1.1e-37 128.3 3.4 1.1e-37 128.3 2.4 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf WAC_Acf1_DNA_bd PF10537.4 CEP18139.1 - 9.9e-25 86.6 0.8 3.8e-24 84.8 0.5 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal TBCA PF02970.11 CEP18139.1 - 2.7e-18 65.8 6.8 2.7e-18 65.8 4.7 4.9 4 1 0 4 4 4 1 Tubulin binding cofactor A DDT PF02791.12 CEP18139.1 - 3.4e-08 33.1 0.2 6.9e-08 32.1 0.2 1.5 1 0 0 1 1 1 1 DDT domain WHIM3 PF15614.1 CEP18139.1 - 1.4e-05 24.7 0.2 5.5e-05 22.8 0.2 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 CEP18139.1 - 0.0014 18.4 0.0 0.005 16.7 0.0 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 CEP18139.1 - 0.031 14.2 0.2 0.1 12.6 0.1 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 WLM PF08325.5 CEP18140.1 - 1.2e-40 139.4 0.0 2e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 CEP18140.1 - 9.4e-12 44.1 2.5 1.1e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 CEP18140.1 - 0.0025 18.0 0.2 0.0069 16.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Peptidase_MA_2 PF13485.1 CEP18140.1 - 0.036 14.1 0.6 0.069 13.1 0.3 1.6 1 1 0 1 1 1 0 Peptidase MA superfamily DUF955 PF06114.8 CEP18140.1 - 0.083 12.6 0.2 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF45 PF01863.12 CEP18140.1 - 0.26 11.0 5.2 0.067 12.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 Glyco_hydro_85 PF03644.8 CEP18142.1 - 1.5e-102 342.9 1.9 2.1e-102 342.4 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 efThoc1 PF11957.3 CEP18144.1 - 2.6e-87 293.3 0.7 3.7e-87 292.8 0.5 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Thaumatin PF00314.12 CEP18145.1 - 7.5e-47 159.5 12.1 1.3e-45 155.4 8.4 2.0 1 1 0 1 1 1 1 Thaumatin family Pkinase PF00069.20 CEP18146.1 - 7.4e-77 258.0 0.0 9.9e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18146.1 - 2.6e-41 141.4 0.0 3.7e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CEP18146.1 - 0.00084 18.7 0.2 0.002 17.5 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 CEP18146.1 - 0.0015 17.5 0.0 0.0029 16.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CEP18146.1 - 0.024 14.3 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PACT_coil_coil PF10495.4 CEP18146.1 - 0.039 13.8 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein RNA_pol_Rpb4 PF03874.11 CEP18147.1 - 2.1e-25 89.0 6.8 2.6e-25 88.6 4.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 MxiH PF09392.5 CEP18147.1 - 0.017 15.7 0.2 0.046 14.2 0.1 1.7 1 1 1 2 2 2 0 Type III secretion needle MxiH like DUF4315 PF14193.1 CEP18147.1 - 0.62 10.0 3.9 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) zf-DHHC PF01529.15 CEP18149.1 - 1.2e-17 63.8 5.5 1.4e-17 63.6 3.8 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 CEP18149.1 - 0.51 10.1 6.8 1.2 8.9 4.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon Spt4 PF06093.8 CEP18149.1 - 0.53 10.2 3.5 0.77 9.6 2.4 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger GATA PF00320.22 CEP18149.1 - 1.8 8.0 6.0 0.14 11.5 0.7 1.8 2 0 0 2 2 2 0 GATA zinc finger PAP1 PF08601.5 CEP18151.1 - 1.2e-16 61.3 28.4 5.6e-15 55.8 19.7 2.8 1 1 0 1 1 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 CEP18151.1 - 6.8e-11 41.9 10.2 1.8e-10 40.6 7.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor Phage_lysis PF03245.8 CEP18151.1 - 0.0015 18.4 3.8 0.0015 18.4 2.6 2.1 2 0 0 2 2 2 1 Bacteriophage Rz lysis protein RGS-like PF09128.6 CEP18151.1 - 0.0055 16.2 5.3 0.0094 15.4 3.7 1.4 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain SUI1 PF01253.17 CEP18151.1 - 0.031 14.0 0.2 0.071 12.9 0.0 1.7 2 0 0 2 2 2 0 Translation initiation factor SUI1 Mnd1 PF03962.10 CEP18151.1 - 0.19 11.3 8.6 0.11 12.1 3.3 2.1 2 0 0 2 2 2 0 Mnd1 family bZIP_2 PF07716.10 CEP18151.1 - 0.21 11.4 18.8 1.8 8.4 13.1 2.3 1 1 0 1 1 1 0 Basic region leucine zipper TPR_MLP1_2 PF07926.7 CEP18152.1 - 0.012 15.3 3.0 0.012 15.3 2.1 4.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Thiolase_N PF00108.18 CEP18153.1 - 9.3e-92 306.7 4.0 2.6e-91 305.2 2.8 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEP18153.1 - 3.2e-41 139.6 0.4 3.2e-41 139.6 0.3 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CEP18153.1 - 3.3e-06 26.7 0.5 8.1e-06 25.4 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CEP18153.1 - 0.12 12.0 4.3 0.36 10.5 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acetyltransf_1 PF00583.19 CEP18155.1 - 7e-06 25.9 0.0 1.5e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP18155.1 - 0.0002 21.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CEP18155.1 - 0.0013 18.8 0.1 0.0097 16.0 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 CEP18156.1 - 1.7e-51 175.0 42.9 1e-35 123.1 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CEP18156.1 - 4.4e-06 25.1 26.7 0.00038 18.7 5.2 2.5 2 1 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 CEP18156.1 - 3e-05 22.2 0.2 3e-05 22.2 0.1 2.7 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF2273 PF10031.4 CEP18156.1 - 0.044 13.3 0.0 0.044 13.3 0.0 4.4 4 0 0 4 4 4 0 Small integral membrane protein (DUF2273) FAD-oxidase_C PF02913.14 CEP18157.1 - 1.3e-54 185.1 0.2 1.6e-54 184.8 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CEP18157.1 - 1.5e-36 124.9 0.2 2.8e-36 124.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.22 CEP18158.1 - 4e-68 225.1 4.5 6.1e-23 80.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L23 PF00276.15 CEP18159.1 - 5.8e-19 67.8 0.1 8.8e-19 67.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 zf-C2H2 PF00096.21 CEP18160.1 - 1.6e-10 40.6 21.3 0.00011 22.2 0.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP18160.1 - 9.7e-09 35.0 27.6 3.9e-07 30.0 1.2 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP18160.1 - 2e-08 33.9 20.6 0.00066 19.8 0.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP18160.1 - 0.054 13.6 7.3 4.8 7.4 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP18160.1 - 0.49 10.6 5.9 2.2 8.6 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Peptidase_S8 PF00082.17 CEP18161.1 - 8.6e-35 120.2 9.6 4.2e-30 104.8 0.4 2.3 1 1 1 2 2 2 2 Subtilase family Ribosomal_S11 PF00411.14 CEP18162.1 - 5.4e-24 84.4 1.2 5.4e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S11 zf-met PF12874.2 CEP18163.1 - 3.4e-07 30.2 1.8 3.4e-07 30.2 1.2 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 CEP18163.1 - 0.00024 20.6 0.3 0.00038 20.0 0.2 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 CEP18163.1 - 0.041 13.1 0.6 0.07 12.4 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CENP-P PF13096.1 CEP18164.1 - 0.0013 18.0 0.2 0.0028 16.9 0.1 1.5 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Nop14 PF04147.7 CEP18164.1 - 0.18 9.7 30.7 0.23 9.3 21.3 1.2 1 0 0 1 1 1 0 Nop14-like family zf-RVT PF13966.1 CEP18166.1 - 9.5e-05 22.6 0.4 0.00016 21.9 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Mito_carr PF00153.22 CEP18167.1 - 1.4e-75 249.0 6.6 2.3e-28 97.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TT_ORF1 PF02956.9 CEP18167.1 - 0.049 12.0 0.3 0.072 11.5 0.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 PTR2 PF00854.16 CEP18168.1 - 1.4e-57 195.2 17.5 1.2e-55 188.8 9.7 2.8 2 1 0 2 2 2 1 POT family MFS_1 PF07690.11 CEP18168.1 - 9.3e-07 27.8 23.8 2.8e-06 26.2 15.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3087 PF11286.3 CEP18168.1 - 0.083 12.1 0.2 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF4231 PF14015.1 CEP18168.1 - 1.5 8.7 6.2 1.2 9.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DOT1 PF08123.8 CEP18169.1 - 3.7e-68 228.8 0.1 7.2e-68 227.9 0.1 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 SWIRM PF04433.12 CEP18169.1 - 1.6e-31 108.2 0.2 1.2e-30 105.4 0.0 2.5 2 0 0 2 2 2 1 SWIRM domain Methyltransf_26 PF13659.1 CEP18169.1 - 1.5e-07 31.4 0.4 6.8e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP18169.1 - 2e-07 30.6 0.0 2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Myb_DNA-bind_6 PF13921.1 CEP18169.1 - 2.4e-06 27.5 0.2 8.8e-06 25.7 0.2 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Methyltransf_18 PF12847.2 CEP18169.1 - 0.00014 22.3 0.0 0.00014 22.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP18169.1 - 0.0024 18.3 0.0 0.0082 16.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP18169.1 - 0.0042 17.4 0.1 0.013 15.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP18169.1 - 0.0085 16.5 1.2 0.02 15.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 CEP18169.1 - 0.062 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Mtp PF03821.11 CEP18170.1 - 0.007 15.7 0.3 0.013 14.9 0.2 1.5 1 1 0 1 1 1 1 Golgi 4-transmembrane spanning transporter MARVEL PF01284.18 CEP18170.1 - 0.014 15.2 9.1 0.023 14.5 6.3 1.4 1 0 0 1 1 1 0 Membrane-associating domain RDD PF06271.7 CEP18170.1 - 0.036 13.9 5.0 0.34 10.8 0.8 2.2 2 0 0 2 2 2 0 RDD family FixQ PF05545.6 CEP18170.1 - 6.7 6.4 7.2 0.74 9.4 0.7 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Med15 PF09606.5 CEP18170.1 - 9.9 4.2 7.0 13 3.8 4.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RRM_1 PF00076.17 CEP18172.1 - 3.4e-14 52.2 0.0 5.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP18172.1 - 1.8e-09 37.4 0.0 3.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP18172.1 - 0.00018 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox PF00046.24 CEP18173.1 - 1.2e-13 50.4 5.0 2.5e-13 49.4 3.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP18173.1 - 0.0092 15.6 0.6 0.025 14.2 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain BSP_II PF05432.6 CEP18173.1 - 0.016 14.5 2.2 0.016 14.5 1.5 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ZapA PF05164.8 CEP18173.1 - 0.13 12.2 1.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapA TraC PF07820.7 CEP18173.1 - 0.14 12.3 4.6 1.3 9.2 0.1 2.7 2 1 1 3 3 3 0 TraC-like protein TLP-20 PF06088.6 CEP18173.1 - 1.7 8.2 8.0 0.75 9.4 3.8 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DctQ PF04290.7 CEP18174.1 - 0.012 15.3 3.7 0.012 15.3 2.6 1.7 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component UbiA PF01040.13 CEP18174.1 - 0.31 10.2 7.8 0.5 9.5 3.8 2.0 2 0 0 2 2 2 0 UbiA prenyltransferase family LIM PF00412.17 CEP18175.1 - 1.4e-19 69.8 28.1 2.4e-07 30.7 3.6 4.0 3 1 0 3 3 3 3 LIM domain NinF PF05810.7 CEP18175.1 - 0.0011 18.7 9.0 0.84 9.4 0.4 4.6 4 0 0 4 4 4 2 NinF protein Zn_ribbon_2 PF12674.2 CEP18175.1 - 5.3 7.4 9.6 2.5 8.5 0.3 3.4 3 0 0 3 3 3 0 Putative zinc ribbon domain SAC3_GANP PF03399.11 CEP18177.1 - 4.5e-58 196.1 4.0 7.7e-58 195.4 2.8 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CEP18177.1 - 0.0001 22.1 1.5 0.00018 21.3 0.2 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF2011 PF09428.5 CEP18177.1 - 0.0035 17.2 2.2 0.0035 17.2 1.5 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) zf-CCHC_6 PF15288.1 CEP18179.1 - 0.07 12.8 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle AAA PF00004.24 CEP18180.1 - 5.2e-38 130.2 0.0 1.1e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP18180.1 - 9.3e-08 32.2 0.4 0.0001 22.4 0.1 3.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CEP18180.1 - 9.6e-07 28.7 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP18180.1 - 1.4e-06 28.4 0.5 3.3e-05 23.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 CEP18180.1 - 5e-06 25.7 0.0 1.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CEP18180.1 - 8.7e-06 25.5 0.1 6.1e-05 22.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CEP18180.1 - 1.8e-05 25.5 0.0 5.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CEP18180.1 - 2.5e-05 24.2 0.0 7.5e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CEP18180.1 - 6.7e-05 22.7 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CEP18180.1 - 0.00035 20.0 0.2 0.03 13.7 0.2 2.3 1 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CEP18180.1 - 0.00044 19.4 0.0 0.00077 18.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 CEP18180.1 - 0.00049 19.3 0.2 0.0013 17.9 0.1 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CEP18180.1 - 0.00076 19.6 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 CEP18180.1 - 0.00086 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CEP18180.1 - 0.00096 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CEP18180.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 CEP18180.1 - 0.0012 18.5 0.1 0.0071 16.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 CEP18180.1 - 0.0022 18.2 0.0 0.0063 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 CEP18180.1 - 0.0023 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Guanylate_kin PF00625.16 CEP18180.1 - 0.0032 16.9 0.1 0.04 13.3 0.0 2.6 2 1 1 3 3 3 1 Guanylate kinase Rad17 PF03215.10 CEP18180.1 - 0.0032 16.2 0.0 0.0053 15.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 CEP18180.1 - 0.0034 16.1 0.0 0.006 15.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Bac_DnaA PF00308.13 CEP18180.1 - 0.0048 16.5 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_24 PF13479.1 CEP18180.1 - 0.0057 16.2 0.2 0.011 15.3 0.2 1.5 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CEP18180.1 - 0.0065 15.6 0.0 0.13 11.3 0.0 2.3 1 1 1 2 2 2 1 KaiC Arch_ATPase PF01637.13 CEP18180.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 CEP18180.1 - 0.011 15.1 0.1 0.98 8.7 0.0 2.7 1 1 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 CEP18180.1 - 0.017 14.0 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_21 PF13304.1 CEP18180.1 - 0.022 14.7 0.1 4.5 7.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 CEP18180.1 - 0.025 14.3 0.1 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 CEP18180.1 - 0.027 14.1 0.1 0.09 12.4 0.0 2.0 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CEP18180.1 - 0.029 13.2 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 CEP18180.1 - 0.032 13.7 0.0 0.085 12.3 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 CEP18180.1 - 0.034 13.7 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CEP18180.1 - 0.043 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 CEP18180.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase tRNA_lig_kinase PF08303.6 CEP18180.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain NB-ARC PF00931.17 CEP18180.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CPT PF07931.7 CEP18180.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATP-synt_ab PF00006.20 CEP18180.1 - 0.091 12.2 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SWIM PF04434.12 CEP18181.1 - 0.0083 15.5 0.6 0.013 14.9 0.4 1.3 1 0 0 1 1 1 1 SWIM zinc finger KduI PF04962.7 CEP18182.1 - 0.047 12.7 2.5 0.077 12.0 1.7 1.2 1 0 0 1 1 1 0 KduI/IolB family MatE PF01554.13 CEP18183.1 - 5.9e-58 195.0 25.6 2.1e-30 105.4 5.8 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 CEP18183.1 - 3.8e-07 30.0 17.2 6.1e-06 26.0 4.4 3.9 3 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain ING PF12998.2 CEP18184.1 - 0.0065 16.7 0.2 0.0065 16.7 0.1 2.2 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Oxidored_nitro PF00148.14 CEP18184.1 - 0.084 11.4 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase TUSC2 PF15000.1 CEP18185.1 - 0.08 13.0 1.0 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor candidate 2 UPF0561 PF10573.4 CEP18185.1 - 0.93 9.3 4.4 0.39 10.5 0.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 G-patch PF01585.18 CEP18186.1 - 1e-11 44.3 5.3 1.3e-11 44.0 2.4 2.1 1 1 1 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CEP18186.1 - 0.04 13.7 2.3 0.081 12.7 0.8 2.2 1 1 1 2 2 2 0 DExH-box splicing factor binding site IncA PF04156.9 CEP18186.1 - 0.098 12.2 14.0 0.02 14.4 4.9 2.1 2 0 0 2 2 2 0 IncA protein GET2 PF08690.5 CEP18186.1 - 1.1 8.4 7.2 0.97 8.6 0.1 2.7 3 0 0 3 3 3 0 GET complex subunit GET2 ADIP PF11559.3 CEP18186.1 - 3 7.7 19.1 0.088 12.7 8.7 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Amidohydro_1 PF01979.15 CEP18187.1 - 5.2e-16 59.2 0.2 2.3e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CEP18187.1 - 6.7e-11 42.7 0.0 7.2e-05 22.9 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CEP18187.1 - 1.2e-07 31.4 0.0 3.5e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CEP18187.1 - 2e-05 24.0 0.3 5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family ALG3 PF05208.8 CEP18188.1 - 1.2e-130 436.0 24.0 1.6e-130 435.6 16.6 1.1 1 0 0 1 1 1 1 ALG3 protein NST1 PF13945.1 CEP18189.1 - 0.091 12.8 5.0 0.097 12.7 3.4 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF1754 PF08555.5 CEP18189.1 - 0.1 13.2 8.6 0.15 12.7 5.9 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) AAA PF00004.24 CEP18191.1 - 3.4e-13 49.9 0.1 1.2e-12 48.1 0.1 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP18191.1 - 1.3e-12 47.9 0.1 3.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP18191.1 - 1.9e-11 44.2 0.0 4.6e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.6 CEP18191.1 - 5.1e-07 29.3 0.4 2e-06 27.4 0.3 2.0 1 0 0 1 1 1 1 CDC6, C terminal DUF2075 PF09848.4 CEP18191.1 - 9.8e-06 24.7 0.0 1.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CEP18191.1 - 4.9e-05 23.1 0.1 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CEP18191.1 - 8.6e-05 22.2 0.3 0.00023 20.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 CEP18191.1 - 9.2e-05 21.4 0.1 0.00017 20.5 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.1 CEP18191.1 - 0.00037 20.1 0.0 0.0011 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 CEP18191.1 - 0.0026 17.2 0.3 0.0083 15.5 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CEP18191.1 - 0.0051 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CEP18191.1 - 0.017 14.8 0.2 0.71 9.5 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 CEP18191.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 CEP18191.1 - 0.15 12.9 0.0 0.42 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CEP18191.1 - 9 5.7 12.0 0.17 11.4 1.5 3.1 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 CEP18192.1 - 6.7e-57 192.6 0.0 1.6e-56 191.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18192.1 - 1.8e-19 69.8 0.0 3.6e-19 68.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CEP18192.1 - 0.00037 19.6 0.0 0.0007 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP18192.1 - 0.019 14.7 0.0 0.065 12.9 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP18192.1 - 0.019 14.5 0.1 0.04 13.5 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 CEP18192.1 - 0.023 13.6 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CEP18192.1 - 0.034 13.4 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 CEP18192.1 - 0.045 13.0 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF4476 PF14771.1 CEP18192.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) ABC_tran PF00005.22 CEP18193.1 - 8.5e-26 90.8 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CEP18193.1 - 3.2e-09 37.1 0.0 8.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 CEP18193.1 - 2.8e-05 23.7 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 CEP18193.1 - 0.00015 21.8 0.0 0.00041 20.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CEP18193.1 - 0.00017 21.2 0.1 0.00044 19.9 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CEP18193.1 - 0.00027 21.0 0.0 0.00042 20.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CEP18193.1 - 0.00089 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CEP18193.1 - 0.00093 18.4 0.0 0.0035 16.6 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 CEP18193.1 - 0.0011 18.6 0.1 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 CEP18193.1 - 0.0013 18.2 0.1 0.0044 16.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CEP18193.1 - 0.0015 17.7 0.0 0.0084 15.2 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 CEP18193.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP18193.1 - 0.0024 17.7 0.0 0.0052 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP18193.1 - 0.0029 18.4 0.1 0.0071 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CEP18193.1 - 0.0033 17.0 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 CEP18193.1 - 0.0075 16.1 0.1 0.11 12.4 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 CEP18193.1 - 0.008 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CEP18193.1 - 0.0097 14.6 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CEP18193.1 - 0.02 14.5 0.1 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 CEP18193.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 CEP18193.1 - 0.029 14.2 0.0 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CEP18193.1 - 0.043 14.1 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CEP18193.1 - 0.048 13.1 0.1 0.079 12.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CEP18193.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 CEP18193.1 - 0.08 13.1 0.2 0.22 11.7 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CEP18193.1 - 0.081 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ABC_ATPase PF09818.4 CEP18193.1 - 0.094 11.2 0.1 9.6 4.6 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.1 CEP18193.1 - 0.094 12.6 0.2 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.21 CEP18194.1 - 2.6e-11 43.1 11.9 7.1e-06 26.0 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP18194.1 - 1.1e-09 38.0 11.0 2.3e-08 33.9 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP18194.1 - 2.3e-09 36.9 10.6 0.00014 21.9 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CEP18194.1 - 5e-05 23.3 4.9 0.14 12.4 0.5 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP18194.1 - 0.00016 21.7 1.9 0.2 11.8 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CEP18194.1 - 0.0059 16.7 3.1 0.013 15.5 2.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.2 CEP18194.1 - 0.012 15.5 1.1 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-binding zf-C2HC_2 PF13913.1 CEP18194.1 - 0.027 14.1 8.0 0.12 12.0 2.0 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 CEP18194.1 - 0.039 13.8 3.9 3.4 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CEP18194.1 - 0.043 14.0 6.3 0.14 12.4 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF2225 PF09986.4 CEP18194.1 - 0.056 12.9 6.0 0.59 9.5 1.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) GAGA PF09237.6 CEP18194.1 - 0.14 11.7 6.9 1.6 8.3 0.6 2.3 1 1 1 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.2 CEP18194.1 - 0.16 12.1 11.5 0.14 12.3 1.7 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) PAS_3 PF08447.6 CEP18195.1 - 6.4e-08 32.5 0.1 0.0029 17.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold LHH PF14411.1 CEP18195.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 A nuclease of the HNH/ENDO VII superfamily with conserved LHH PAS_11 PF14598.1 CEP18195.1 - 0.015 15.2 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 PAS domain PAS_9 PF13426.1 CEP18195.1 - 0.04 14.2 0.0 0.36 11.2 0.0 2.2 2 1 0 2 2 2 0 PAS domain Metallophos PF00149.23 CEP18196.1 - 1.2e-39 135.8 0.3 1.7e-39 135.3 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zds_C PF08632.5 CEP18197.1 - 6.2e-09 35.1 0.6 3.1e-08 32.8 0.1 2.1 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term RNA_pol PF00940.14 CEP18198.1 - 5.5e-164 545.4 0.0 9.7e-164 544.6 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CEP18198.1 - 8.4e-83 278.2 0.0 2.7e-82 276.5 0.0 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 CEP18198.1 - 2.3e-06 27.4 0.1 7.6e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family ParA PF10609.4 CEP18199.1 - 3e-36 123.1 0.0 5.3e-36 122.3 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CEP18199.1 - 1.1e-14 54.3 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CEP18199.1 - 0.00018 20.6 0.1 0.00082 18.5 0.0 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 CEP18199.1 - 0.0029 17.0 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 CEP18199.1 - 0.0031 16.6 0.0 0.0085 15.2 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CEP18199.1 - 0.0041 17.0 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CEP18199.1 - 0.0083 15.3 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_26 PF13500.1 CEP18199.1 - 0.0087 15.6 0.0 0.32 10.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain TF_Zn_Ribbon PF08271.7 CEP18199.1 - 0.033 13.5 0.1 0.11 11.8 0.1 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding Fer4_NifH PF00142.13 CEP18199.1 - 0.034 13.3 0.0 2.7 7.0 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.1 CEP18199.1 - 0.054 13.4 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain YjeF_N PF03853.10 CEP18199.1 - 0.091 12.3 0.0 0.91 9.1 0.0 2.3 3 0 0 3 3 3 0 YjeF-related protein N-terminus SNARE PF05739.14 CEP18200.1 - 1.4e-09 37.5 3.7 1.4e-09 37.5 2.6 2.8 2 1 1 3 3 3 1 SNARE domain DUF1178 PF06676.6 CEP18200.1 - 0.069 13.3 1.4 0.9 9.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) MutS_IV PF05190.13 CEP18200.1 - 0.14 12.3 4.7 0.16 12.1 0.6 2.6 2 1 0 2 2 2 0 MutS family domain IV TBCA PF02970.11 CEP18200.1 - 2 8.5 12.6 0.056 13.5 1.5 2.9 2 2 0 2 2 2 0 Tubulin binding cofactor A AKNA PF12443.3 CEP18200.1 - 4.5 7.3 10.9 5.3 7.1 0.1 3.1 3 0 0 3 3 3 0 AT-hook-containing transcription factor CCDC-167 PF15188.1 CEP18200.1 - 4.7 7.2 12.8 6.7 6.7 0.7 3.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 FUSC-like PF12805.2 CEP18200.1 - 5 5.9 6.3 0.57 9.0 1.3 1.7 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS Pkinase PF00069.20 CEP18201.1 - 3e-67 226.4 0.0 5.1e-67 225.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18201.1 - 2.1e-31 108.9 0.0 3.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CEP18201.1 - 1.1e-09 38.7 5.5 1.1e-09 38.7 3.8 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEP18201.1 - 0.0098 14.8 0.0 0.036 13.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF3127 PF11325.3 CEP18201.1 - 0.051 13.5 0.1 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) APH PF01636.18 CEP18201.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PDEase_I PF00233.14 CEP18202.1 - 6.8e-54 183.1 2.8 1.6e-52 178.6 1.9 2.5 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase LAG1-DNAbind PF09271.6 CEP18203.1 - 4.3e-30 105.0 14.2 5.9e-30 104.5 4.4 3.5 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 CEP18203.1 - 2.4e-24 85.8 1.1 1.2e-14 54.3 0.0 3.5 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain Polysacc_deac_1 PF01522.16 CEP18204.1 - 2.3e-27 95.0 0.0 3.6e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 CEP18204.1 - 0.013 14.9 0.2 0.017 14.5 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF2745 PF10922.3 CEP18204.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2745) Myb_DNA-binding PF00249.26 CEP18204.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Hexokinase_1 PF00349.16 CEP18205.1 - 7.7e-48 162.5 0.0 1.3e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CEP18205.1 - 2.2e-47 161.3 0.7 2.8e-47 160.9 0.5 1.1 1 0 0 1 1 1 1 Hexokinase Nsp1_C PF05064.8 CEP18205.1 - 0.011 15.3 0.3 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Adaptin_N PF01602.15 CEP18206.1 - 1.2e-153 512.2 11.7 1.5e-153 511.9 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CEP18206.1 - 6.1e-23 81.5 8.7 7.6e-23 81.2 0.4 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CEP18206.1 - 4.8e-20 71.6 1.2 2.3e-09 37.4 0.0 6.2 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.17 CEP18206.1 - 3.2e-10 39.2 5.7 0.003 17.4 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 CEP18206.1 - 4.2e-07 30.2 0.3 0.069 13.6 0.0 5.9 6 1 1 7 7 7 1 HEAT-like repeat Cnd3 PF12719.2 CEP18206.1 - 6e-05 22.1 3.5 0.00032 19.8 0.1 3.0 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 CEP18206.1 - 0.00011 21.6 1.2 0.015 14.6 0.0 3.5 4 1 0 4 4 4 1 CLASP N terminal Arm PF00514.18 CEP18206.1 - 0.0038 16.9 2.8 2.9 7.8 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 CEP18206.1 - 0.0078 15.9 0.2 6 6.6 0.0 3.2 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain DUF1548 PF07579.6 CEP18206.1 - 0.097 12.7 1.6 2 8.5 0.0 3.4 2 2 2 4 4 4 0 Domain of Unknown Function (DUF1548) DUF4588 PF15251.1 CEP18206.1 - 1 9.2 3.6 14 5.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4588) DUF3316 PF11777.3 CEP18207.1 - 0.016 14.9 0.0 0.41 10.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3316) SNase PF00565.12 CEP18208.1 - 1.8e-66 221.1 0.3 2.8e-20 72.5 0.0 5.2 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 CEP18208.1 - 2e-29 101.9 0.0 5.9e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 Tudor domain Porin_OmpG PF09381.5 CEP18208.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) Glyco_transf_20 PF00982.16 CEP18209.1 - 5.9e-162 539.4 0.0 8.3e-162 538.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEP18209.1 - 2e-78 262.5 0.1 3.5e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 CEP18209.1 - 0.0076 15.7 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 CEP18209.1 - 0.016 15.3 0.0 0.071 13.2 0.0 2.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 HAD PF12710.2 CEP18209.1 - 0.05 13.7 0.7 9.2 6.3 0.0 2.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase 6PF2K PF01591.13 CEP18210.1 - 0.038 13.0 0.5 0.062 12.3 0.3 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GPI-anchored PF10342.4 CEP18211.1 - 1.2e-11 44.8 0.3 1.2e-11 44.8 0.2 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Wzt_C PF14524.1 CEP18211.1 - 0.02 14.6 0.0 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Wzt C-terminal domain Mucin PF01456.12 CEP18211.1 - 6.1 6.6 18.7 14 5.4 12.3 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein AA_permease PF00324.16 CEP18212.1 - 5.2e-132 440.5 46.4 5.9e-132 440.3 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEP18212.1 - 2.7e-44 151.4 51.4 3.5e-44 151.0 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L12 PF00542.14 CEP18213.1 - 1.6e-21 76.0 12.5 4.3e-21 74.6 6.9 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DUF2267 PF10025.4 CEP18213.1 - 0.003 17.6 0.7 0.0079 16.2 0.3 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) CSTF2_hinge PF14327.1 CEP18213.1 - 0.074 13.1 0.2 8.4 6.5 0.1 2.3 2 1 1 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 S1 PF00575.18 CEP18214.1 - 8.4e-54 179.5 28.5 1.5e-08 34.6 0.1 10.1 10 1 0 10 10 10 9 S1 RNA binding domain Suf PF05843.9 CEP18214.1 - 8.1e-10 38.8 0.7 8.1e-10 38.8 0.5 5.5 3 1 3 6 6 6 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 CEP18214.1 - 2.5e-06 27.9 0.0 0.0019 18.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEP18214.1 - 5.1e-06 26.7 0.0 0.018 15.3 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP18214.1 - 1.7e-05 25.0 0.0 0.79 10.5 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP18214.1 - 0.00016 21.5 0.0 0.00061 19.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP18214.1 - 0.0028 17.4 0.2 0.039 13.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 CEP18214.1 - 0.0065 15.5 0.1 0.21 10.6 0.0 2.7 1 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEP18214.1 - 0.011 15.3 0.1 0.036 13.7 0.0 1.9 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.1 CEP18214.1 - 0.075 13.5 0.1 35 5.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.23 CEP18215.1 - 1.3e-07 31.1 6.9 5.2e-07 29.2 4.6 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP18215.1 - 0.02 14.7 3.4 0.029 14.2 2.4 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain WRKY PF03106.10 CEP18216.1 - 2e-05 24.3 6.1 4.1e-05 23.3 4.2 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.11 CEP18216.1 - 0.068 13.0 1.0 0.15 11.9 0.7 1.6 1 0 0 1 1 1 0 FLYWCH zinc finger domain Zn_ribbon_recom PF13408.1 CEP18216.1 - 1.5 9.1 4.8 2 8.7 2.4 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF4098 PF13345.1 CEP18219.1 - 5.9e-06 26.1 1.7 5.9e-06 26.1 1.2 3.8 3 1 2 5 5 5 3 Domain of unknown function (DUF4098) DUF4097 PF13349.1 CEP18219.1 - 2 7.9 5.2 30 4.1 0.0 4.4 5 2 1 6 6 6 0 Domain of unknown function (DUF4097) bZIP_2 PF07716.10 CEP18220.1 - 3.3e-10 39.6 10.5 3.3e-10 39.6 7.3 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP18220.1 - 4.4e-05 23.3 7.3 0.0001 22.2 5.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 CEP18220.1 - 0.027 14.3 1.2 0.027 14.3 0.8 1.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF2762 PF10960.3 CEP18220.1 - 0.088 12.5 2.8 0.18 11.5 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) Spt5_N PF11942.3 CEP18220.1 - 9.5 6.9 11.5 33 5.1 6.0 2.6 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.27 CEP18221.1 - 1.4e-69 227.7 24.7 6e-12 44.9 0.5 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP18221.1 - 2.8e-15 55.4 10.0 0.0071 14.5 0.1 6.2 2 1 4 6 6 6 6 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP18221.1 - 1.4e-13 50.3 0.5 2.9e-13 49.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP18221.1 - 1.1e-09 37.6 0.2 2.7e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 CEP18221.1 - 3.4e-07 29.3 0.9 0.55 8.9 0.0 4.2 3 1 1 4 4 4 3 Nup133 N terminal like BBS2_Mid PF14783.1 CEP18221.1 - 0.002 17.8 0.0 1.4 8.6 0.0 3.9 3 2 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region RVT_1 PF00078.22 CEP18222.1 - 5.2e-23 81.5 0.1 1.2e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FUSC_2 PF13515.1 CEP18223.1 - 4.6e-17 62.1 11.9 4.6e-17 62.1 8.2 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 CEP18223.1 - 5.7e-14 51.4 10.1 4.7e-13 48.4 4.0 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 CEP18223.1 - 2.5e-13 50.1 1.0 2.5e-13 50.1 0.7 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) ALMT PF11744.3 CEP18223.1 - 9.7e-13 47.5 11.7 2.9e-11 42.6 1.5 3.0 2 1 0 2 2 2 2 Aluminium activated malate transporter Tape_meas_lam_C PF09718.5 CEP18223.1 - 0.0011 18.8 0.3 0.0038 17.0 0.2 2.0 1 0 0 1 1 1 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pkinase PF00069.20 CEP18224.1 - 5.4e-42 143.7 0.0 7.5e-41 139.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18224.1 - 6.4e-20 71.3 0.0 1.2e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_EZ PF13513.1 CEP18224.1 - 5.4e-18 64.9 6.3 5.3e-10 39.4 0.0 8.5 8 1 2 10 10 10 2 HEAT-like repeat HEAT PF02985.17 CEP18224.1 - 1.6e-17 61.9 10.9 7.7e-05 22.4 0.0 10.4 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 CEP18224.1 - 2.7e-15 56.3 5.8 3.2e-06 27.3 0.0 7.3 3 3 4 7 7 7 3 HEAT repeats IBN_N PF03810.14 CEP18224.1 - 6.8e-13 48.3 1.7 5e-12 45.5 0.4 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.3 CEP18224.1 - 8e-07 28.1 2.0 0.056 12.1 0.0 3.5 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal Arm PF00514.18 CEP18224.1 - 1e-06 28.3 1.9 0.0028 17.3 0.0 4.8 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat APH PF01636.18 CEP18224.1 - 6e-06 26.1 0.0 2.4e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family TIP120 PF08623.5 CEP18224.1 - 0.0015 18.1 1.8 1.1 8.8 0.0 3.7 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) Proteasom_PSMB PF10508.4 CEP18224.1 - 0.0015 16.8 3.3 0.11 10.7 0.0 3.2 2 2 2 4 4 4 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 CEP18224.1 - 0.0038 16.6 5.0 1.2 8.3 0.2 4.4 4 2 0 4 4 4 2 CLASP N terminal Kinase-like PF14531.1 CEP18224.1 - 0.066 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GAS2 PF02187.12 CEP18225.1 - 0.0007 19.3 0.1 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain ALIX_LYPXL_bnd PF13949.1 CEP18225.1 - 0.0024 16.8 0.0 0.0066 15.4 0.0 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1285 PF06938.6 CEP18225.1 - 0.06 13.3 0.2 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1285) KAR9 PF08580.5 CEP18225.1 - 0.11 10.7 50.6 1.1 7.4 3.3 3.3 1 1 1 2 2 2 0 Yeast cortical protein KAR9 CPSase_L_D2 PF02786.12 CEP18226.1 - 2e-80 269.0 0.3 3.6e-80 268.2 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CEP18226.1 - 8e-70 234.2 0.0 1.3e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CEP18226.1 - 5e-33 113.4 0.1 1.5e-32 111.9 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 CEP18226.1 - 3.1e-30 105.5 0.2 1.4e-29 103.4 0.0 2.1 2 0 0 2 2 2 1 HMGL-like Biotin_carb_C PF02785.14 CEP18226.1 - 4.2e-30 103.8 0.0 1.7e-29 101.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 CEP18226.1 - 6.5e-20 71.1 0.8 2.5e-19 69.2 0.1 2.2 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CEP18226.1 - 7.4e-19 67.1 3.8 3.2e-18 65.1 1.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CEP18226.1 - 1e-18 67.7 0.2 2.1e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CEP18226.1 - 9.6e-16 57.1 1.1 3.3e-08 33.0 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CEP18226.1 - 4.6e-12 45.7 0.0 9e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 CEP18226.1 - 3.1e-09 36.5 0.5 0.00018 20.9 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 CEP18226.1 - 1.3e-08 35.0 1.4 0.007 16.6 0.1 3.3 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp PF02222.17 CEP18226.1 - 2.4e-08 33.5 0.1 5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CEP18226.1 - 3.8e-07 29.7 0.2 1.5e-06 27.8 0.2 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CEP18226.1 - 2.4e-05 24.2 0.0 6.5e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 CEP18226.1 - 7e-05 22.1 0.3 0.17 10.9 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein DUF2118 PF09891.4 CEP18226.1 - 0.0014 18.3 0.2 0.0038 16.9 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 CEP18226.1 - 0.0064 16.1 0.0 0.034 13.8 0.1 2.1 2 0 0 2 2 2 1 Glycine cleavage H-protein Clusterin PF01093.12 CEP18227.1 - 0.071 11.9 0.9 0.17 10.6 0.7 1.6 1 1 0 1 1 1 0 Clusterin DDE_3 PF13358.1 CEP18228.1 - 1.1e-22 80.3 0.1 7.8e-17 61.3 0.0 2.8 2 1 1 3 3 3 2 DDE superfamily endonuclease IF-2B PF01008.12 CEP18229.1 - 9.1e-65 218.4 0.1 2e-64 217.3 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 CEP18229.1 - 0.041 13.5 0.8 0.95 9.0 0.0 2.9 3 1 1 4 4 4 0 DeoR C terminal sensor domain DUF4112 PF13430.1 CEP18230.1 - 1.5e-32 111.6 0.6 2.6e-32 110.8 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) TFIID_30kDa PF03540.8 CEP18230.1 - 8e-23 80.0 0.3 1.5e-22 79.1 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 CEP18230.1 - 0.096 12.4 0.9 3.8 7.3 0.1 2.9 2 1 0 2 2 2 0 Bromodomain associated WD40 PF00400.27 CEP18231.1 - 3.3e-20 71.1 1.9 0.0011 18.7 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CEP18231.1 - 0.00011 21.8 0.1 0.0016 17.9 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 CEP18231.1 - 0.056 13.7 0.1 26 5.2 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Pro_CA PF00484.14 CEP18232.1 - 6.3e-49 165.8 0.4 1.1e-48 165.1 0.3 1.3 1 0 0 1 1 1 1 Carbonic anhydrase zf-H2C2_2 PF13465.1 CEP18233.1 - 1.9e-25 87.8 17.3 3.6e-07 30.1 1.1 4.5 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 CEP18233.1 - 1.8e-21 75.1 23.0 1.6e-06 28.0 0.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP18233.1 - 3.1e-14 52.1 18.8 0.0023 18.1 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-TRAF PF02176.13 CEP18233.1 - 0.0081 16.5 15.1 0.057 13.8 2.0 3.3 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 CEP18233.1 - 0.053 13.6 14.3 0.38 10.9 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP18233.1 - 0.083 13.1 12.0 15 5.9 0.1 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type MSA-2c PF12238.3 CEP18233.1 - 0.2 11.3 3.2 0.29 10.7 2.2 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CHORD PF04968.7 CEP18233.1 - 1.3 9.3 14.0 4.6 7.5 0.4 4.3 1 1 4 5 5 5 0 CHORD Aha1_N PF09229.6 CEP18235.1 - 1.3e-36 125.4 2.2 1.9e-36 124.9 1.5 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CEP18235.1 - 3.3e-18 65.9 0.6 5.9e-18 65.1 0.4 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein LTXXQ PF07813.7 CEP18235.1 - 0.028 14.8 0.1 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein Folliculin PF11704.3 CEP18236.1 - 1.5e-34 118.9 0.0 3.3e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Pyrid_oxidase_2 PF13883.1 CEP18236.1 - 9.9e-32 110.0 0.0 2.3e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_S26e PF01283.14 CEP18237.1 - 1.5e-51 173.4 9.4 1.7e-51 173.2 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 CEP18237.1 - 0.086 13.1 2.6 0.34 11.2 0.2 2.1 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_10 PF13237.1 CEP18237.1 - 0.12 12.1 4.2 0.31 10.8 0.9 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CEP18237.1 - 0.27 11.6 3.7 2.9 8.3 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 CEP18237.1 - 0.4 10.7 3.5 0.76 9.8 0.7 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.22 CEP18237.1 - 0.73 9.5 4.3 0.57 9.8 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 CEP18237.1 - 1.8 8.6 4.9 5.5 7.1 3.3 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Glyco_hydro_38 PF01074.17 CEP18238.1 - 1.3e-88 296.8 0.4 3.3e-88 295.5 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CEP18238.1 - 8.2e-74 249.0 4.1 1.4e-73 248.2 2.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CEP18238.1 - 6.5e-16 58.3 0.1 2.2e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase, middle domain zf-C2H2 PF00096.21 CEP18238.1 - 9.1e-13 47.7 5.5 1.8e-05 24.7 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP18238.1 - 2.4e-09 36.8 4.9 0.00021 21.3 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP18238.1 - 4.2e-09 36.2 13.0 1.4e-05 25.1 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.7 CEP18238.1 - 0.00065 19.7 0.4 0.0014 18.6 0.3 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CEP18238.1 - 0.0011 18.9 0.9 0.011 15.8 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF4455 PF14643.1 CEP18238.1 - 0.0035 16.0 0.7 0.0054 15.4 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) TerY-C PF15616.1 CEP18238.1 - 0.0073 16.2 0.1 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-met PF12874.2 CEP18238.1 - 0.15 12.3 2.1 0.76 10.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GTP_EFTU PF00009.22 CEP18239.1 - 2.2e-24 85.9 0.0 4.5e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEP18239.1 - 6.1e-16 58.4 0.6 2.9e-15 56.2 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEP18239.1 - 1.1e-08 35.0 0.8 3.2e-08 33.5 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CEP18239.1 - 0.00055 19.5 0.1 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CEP18239.1 - 0.022 14.7 0.2 0.061 13.2 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.16 CEP18239.1 - 0.027 13.7 0.2 2 7.6 0.0 2.8 2 0 0 2 2 2 0 ADP-ribosylation factor family Peptidase_M17 PF00883.16 CEP18240.1 - 1.4e-45 155.5 0.0 5e-45 153.7 0.0 1.9 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain PGAP1 PF07819.8 CEP18241.1 - 1.3e-06 28.1 0.1 2.3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CEP18241.1 - 6.9e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP18241.1 - 0.00012 21.6 0.0 0.0003 20.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 CEP18241.1 - 0.0027 17.0 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CEP18241.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CEP18241.1 - 0.01 14.9 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 CEP18241.1 - 0.012 14.6 0.0 0.039 12.9 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase SET PF00856.23 CEP18242.1 - 0.0038 17.5 0.1 0.082 13.2 0.0 2.7 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 CEP18242.1 - 0.44 10.4 26.1 0.17 11.7 11.7 2.5 2 0 0 2 2 2 0 MYND finger HTH_29 PF13551.1 CEP18247.1 - 0.0001 22.4 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP18247.1 - 0.00068 19.2 0.0 0.0018 17.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 CEP18247.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_psq PF05225.11 CEP18247.1 - 0.0018 17.8 0.0 0.0043 16.5 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 CEP18247.1 - 0.0046 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.1 CEP18247.1 - 0.0047 16.4 0.1 0.045 13.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP18247.1 - 0.0092 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_1 PF00126.22 CEP18247.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CENP-B_N PF04218.8 CEP18247.1 - 0.014 14.7 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NUMOD1 PF07453.8 CEP18247.1 - 0.033 14.0 0.0 0.095 12.5 0.0 1.8 1 0 0 1 1 1 0 NUMOD1 domain MerR_1 PF13411.1 CEP18247.1 - 0.043 13.5 0.4 0.4 10.4 0.0 2.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein HTH_3 PF01381.17 CEP18247.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix SpoIIID PF12116.3 CEP18247.1 - 0.072 13.0 0.3 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein D HTH_8 PF02954.14 CEP18247.1 - 0.073 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family MarR PF01047.17 CEP18247.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 CEP18247.1 - 0.12 11.8 0.3 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Aldo_ket_red PF00248.16 CEP18248.1 - 2.8e-48 164.1 0.1 3.3e-48 163.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Arf PF00025.16 CEP18249.1 - 2e-76 255.1 0.1 2.9e-76 254.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CEP18249.1 - 1.4e-13 50.5 0.0 2.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CEP18249.1 - 1e-12 47.5 0.4 8.3e-09 34.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CEP18249.1 - 3.2e-11 42.7 0.0 5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEP18249.1 - 8.8e-11 41.3 0.0 1.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP18249.1 - 3.5e-08 33.9 0.0 7.7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CEP18249.1 - 4.9e-06 26.1 0.1 5.7e-05 22.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP18249.1 - 3.7e-05 23.6 0.0 7.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CEP18249.1 - 0.032 14.5 0.6 0.19 12.0 0.4 2.0 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 CEP18249.1 - 0.048 13.1 0.3 9.9 5.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.27 CEP18250.1 - 6.4e-48 158.9 13.8 4.6e-10 38.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat W_rich_C PF07483.6 CEP18250.1 - 0.0083 15.8 1.1 0.02 14.5 0.6 1.8 1 1 0 1 1 1 1 Tryptophan-rich Synechocystis species C-terminal domain Methyltransf_11 PF08241.7 CEP18251.1 - 5.6e-11 42.7 0.0 1.8e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP18251.1 - 8.3e-09 35.3 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP18251.1 - 5.6e-06 26.0 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP18251.1 - 0.00016 22.1 0.0 0.00033 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP18251.1 - 0.00033 21.0 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP18251.1 - 0.0007 19.9 0.0 0.004 17.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP18251.1 - 0.033 13.2 0.0 0.11 11.6 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CEP18251.1 - 0.054 12.5 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase BLOC1_2 PF10046.4 CEP18252.1 - 0.0084 16.2 1.1 0.017 15.2 0.5 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sulfatase_C PF14707.1 CEP18252.1 - 0.049 13.9 0.2 0.049 13.9 0.2 1.8 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase RPE65 PF03055.10 CEP18253.1 - 8e-90 301.7 0.1 9.9e-90 301.4 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AIP3 PF03915.8 CEP18254.1 - 8.6e-70 235.7 46.1 1.1e-56 192.6 22.8 2.6 2 1 1 3 3 3 2 Actin interacting protein 3 MitMem_reg PF13012.1 CEP18254.1 - 0.064 13.3 6.5 0.1 12.6 2.7 2.7 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function FliL PF03748.9 CEP18254.1 - 0.1 12.6 4.4 0.15 12.0 0.1 3.4 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL HsbA PF12296.3 CEP18254.1 - 0.13 12.1 5.5 1.2 8.9 0.0 4.0 3 1 0 3 3 3 0 Hydrophobic surface binding protein A A2M_N PF01835.14 CEP18255.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 MG2 domain APG9 PF04109.11 CEP18256.1 - 9.6e-158 524.9 2.4 1.2e-157 524.6 1.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Aldedh PF00171.17 CEP18257.1 - 4.9e-98 328.4 0.0 6.1e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HOASN PF14515.1 CEP18257.1 - 0.028 14.8 0.2 0.055 13.8 0.2 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices dCMP_cyt_deam_1 PF00383.17 CEP18258.1 - 9.5e-21 73.3 0.2 1.2e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 CEP18258.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 CEP18258.1 - 0.0015 18.2 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase MafB19-deam PF14437.1 CEP18258.1 - 0.025 14.1 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase Indigoidine_A PF04227.7 CEP18258.1 - 0.042 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein Cyclin PF08613.6 CEP18259.1 - 4.5e-16 59.5 0.0 7.4e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP18259.1 - 2.4e-07 30.3 0.0 4.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4536 PF15055.1 CEP18259.1 - 0.085 12.9 0.1 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) SWI-SNF_Ssr4 PF08549.5 CEP18260.1 - 6e-06 24.8 3.8 6e-06 24.8 2.7 2.0 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1750) LMBR1 PF04791.11 CEP18260.1 - 0.16 10.5 6.6 0.23 10.0 4.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.4 CEP18260.1 - 1.3 7.1 61.9 0.36 9.0 8.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Neuro_bHLH PF12533.3 CEP18260.1 - 7.2 7.4 25.7 4.2 8.2 9.9 2.7 2 0 0 2 2 2 0 Neuronal helix-loop-helix transcription factor Proteasome PF00227.21 CEP18261.1 - 6e-48 162.6 0.0 7.6e-48 162.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEP18261.1 - 4.4e-13 48.2 0.1 7.5e-13 47.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HATPase_c PF02518.21 CEP18262.1 - 1.4e-28 98.8 0.0 3.3e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEP18262.1 - 1.2e-26 92.8 0.5 5.3e-24 84.3 0.4 2.6 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CEP18262.1 - 1.1e-15 57.3 1.3 4.1e-15 55.5 0.9 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain NDK PF00334.14 CEP18263.1 - 7.5e-33 113.1 0.0 1.7e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 Nucleoside diphosphate kinase AMP-binding PF00501.23 CEP18264.1 - 1.9e-93 313.1 0.0 2.5e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NOA36 PF06524.7 CEP18265.1 - 4.3 6.5 9.8 5.3 6.2 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein FAR1 PF03101.10 CEP18266.1 - 6.4e-06 26.6 2.1 6.4e-06 26.6 1.4 3.3 4 0 0 4 4 4 1 FAR1 DNA-binding domain MBOAT_2 PF13813.1 CEP18267.1 - 2.3e-07 30.7 1.4 2.3e-07 30.7 1.0 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Sugar_tr PF00083.19 CEP18268.1 - 4.6e-36 124.3 30.7 6.3e-35 120.6 21.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP18268.1 - 7.8e-36 123.5 35.0 1.2e-35 122.9 24.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CEP18268.1 - 9.7e-08 30.8 19.6 8.5e-07 27.7 7.5 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 CEP18268.1 - 1.5e-07 30.2 25.2 0.00024 19.7 5.0 2.2 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 CEP18268.1 - 7.4e-05 22.4 4.3 0.059 13.1 0.0 2.8 2 0 0 2 2 2 2 MFS_1 like family UPF0122 PF04297.9 CEP18268.1 - 0.07 13.1 0.0 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Ta0938 PF11494.3 CEP18268.1 - 0.35 11.0 3.2 0.18 11.9 0.4 1.8 2 0 0 2 2 2 0 Ta0938 DUF4389 PF14333.1 CEP18268.1 - 0.38 10.5 4.1 0.33 10.7 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) SpoVAB PF13782.1 CEP18268.1 - 8.8 6.3 9.6 6.5 6.7 0.6 3.2 3 0 0 3 3 3 0 Stage V sporulation protein AB RNA_pol_Rpb6 PF01192.17 CEP18269.1 - 1.9e-20 72.3 1.1 2.5e-20 71.9 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 Ceramidase_alk PF04734.8 CEP18270.1 - 1.4e-238 793.2 1.0 1.5e-238 793.0 0.7 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase MR_MLE_C PF13378.1 CEP18271.1 - 7.1e-18 64.6 0.0 1.5e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 CEP18271.1 - 4.9e-14 52.6 0.2 1.4e-13 51.1 0.1 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain EBP PF05241.7 CEP18271.1 - 3.8e-07 29.3 3.0 6e-07 28.6 2.1 1.3 1 0 0 1 1 1 1 Emopamil binding protein MR_MLE_N PF02746.11 CEP18271.1 - 0.00022 21.2 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Hus1 PF04005.7 CEP18272.1 - 3.2e-50 170.7 0.0 5e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Hus1-like protein DUF3336 PF11815.3 CEP18273.1 - 6.6e-33 113.2 1.3 1.1e-32 112.5 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CEP18273.1 - 5.6e-21 75.4 0.0 1.4e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Glyco_transf_49 PF13896.1 CEP18274.1 - 3.7e-39 134.7 0.5 2.7e-31 108.8 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CEP18274.1 - 0.00015 20.9 0.4 0.00041 19.5 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CEP18274.1 - 0.006 16.8 0.4 0.015 15.6 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Pkinase PF00069.20 CEP18275.1 - 6.1e-73 245.1 0.0 7.9e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18275.1 - 8.5e-33 113.5 0.0 1.4e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP18275.1 - 0.0017 17.4 0.7 0.0037 16.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CEP18275.1 - 0.0092 14.9 0.0 0.25 10.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CEP18275.1 - 0.012 15.3 0.1 0.03 14.0 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family MTP18 PF10558.4 CEP18276.1 - 8.5e-56 187.9 0.5 1.1e-55 187.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) PTPA PF03095.10 CEP18277.1 - 3.7e-116 387.4 0.2 4.4e-116 387.2 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Urb2 PF10441.4 CEP18278.1 - 5.7e-31 107.8 4.6 5.7e-31 107.8 3.2 4.6 4 1 0 4 4 4 1 Urb2/Npa2 family DUF721 PF05258.7 CEP18278.1 - 0.032 14.4 0.0 6.5 7.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF721) SapB_1 PF05184.10 CEP18278.1 - 0.75 9.6 5.9 13 5.7 0.3 3.7 3 0 0 3 3 3 0 Saposin-like type B, region 1 C2 PF00168.25 CEP18279.1 - 2.5e-76 251.5 11.6 7.7e-18 64.1 0.1 5.9 6 0 0 6 6 6 5 C2 domain Ras PF00071.17 CEP18281.1 - 9.7e-63 210.3 0.2 1.3e-62 210.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP18281.1 - 1.1e-21 77.4 0.1 2e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP18281.1 - 2.4e-13 49.7 0.1 3.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEP18281.1 - 6.2e-07 29.3 0.1 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP18281.1 - 4.4e-05 22.9 0.2 0.00016 21.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEP18281.1 - 8.1e-05 22.7 0.1 0.00034 20.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 CEP18281.1 - 0.00016 20.8 0.0 0.0003 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 CEP18281.1 - 0.00029 20.0 0.1 0.00042 19.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEP18281.1 - 0.0017 17.5 0.0 0.0039 16.4 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CEP18281.1 - 0.0045 16.8 0.1 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP18281.1 - 0.0064 16.5 0.2 0.024 14.6 0.2 2.0 1 1 1 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CEP18281.1 - 0.007 15.5 0.2 0.015 14.4 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CEP18281.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 CEP18281.1 - 0.015 14.9 0.1 0.022 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CEP18281.1 - 0.02 14.1 0.1 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 CEP18281.1 - 0.04 14.2 0.2 0.054 13.7 0.1 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 CEP18281.1 - 0.075 12.6 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain SpoIIID PF12116.3 CEP18281.1 - 0.076 12.9 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D YtzH PF14165.1 CEP18281.1 - 0.084 13.1 0.2 0.35 11.1 0.1 1.9 2 0 0 2 2 2 0 YtzH-like protein AAA_32 PF13654.1 CEP18281.1 - 0.092 11.3 0.1 1.6 7.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 CEP18281.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_L3 PF00297.17 CEP18283.1 - 2.9e-119 397.2 7.8 3.5e-119 397.0 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Laminin_G_3 PF13385.1 CEP18284.1 - 0.04 14.1 0.2 0.04 14.1 0.1 1.9 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Myb_DNA-binding PF00249.26 CEP18286.1 - 5.1e-51 170.5 22.2 9.4e-15 54.4 0.3 6.0 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP18286.1 - 1.6e-38 130.6 21.0 1.6e-15 56.8 0.7 6.6 3 2 3 6 6 6 5 Myb-like DNA-binding domain Tachylectin PF14517.1 CEP18286.1 - 0.066 12.5 0.3 0.12 11.6 0.2 1.4 1 0 0 1 1 1 0 Tachylectin BUD22 PF09073.5 CEP18287.1 - 3.7e-26 92.1 60.8 1.8e-17 63.5 10.9 2.7 1 1 1 2 2 2 2 BUD22 CTP_transf_2 PF01467.21 CEP18288.1 - 1.2e-35 122.8 0.5 3.2e-20 72.7 0.0 2.9 2 1 1 3 3 3 2 Cytidylyltransferase FAD_syn PF06574.7 CEP18288.1 - 0.00016 21.3 1.0 0.72 9.4 0.0 2.9 3 1 0 3 3 3 2 FAD synthetase ScdA_N PF04405.9 CEP18288.1 - 0.054 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) Pantoate_ligase PF02569.10 CEP18288.1 - 0.06 12.1 0.1 4.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase CoA_binding_3 PF13727.1 CEP18288.1 - 0.087 12.6 0.0 0.85 9.4 0.0 2.3 3 0 0 3 3 3 0 CoA-binding domain GPI-anchored PF10342.4 CEP18290.1 - 1.1e-10 41.8 0.3 1.1e-10 41.8 0.2 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF31 PF01732.11 CEP18290.1 - 0.046 13.0 22.5 0.055 12.7 15.6 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) ABC2_membrane_3 PF12698.2 CEP18290.1 - 1.7 7.5 3.7 2.4 7.0 2.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF966 PF06136.8 CEP18290.1 - 1.8 7.9 25.0 2.1 7.6 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) YjgP_YjgQ PF03739.9 CEP18290.1 - 5.3 5.6 6.0 7.7 5.1 4.2 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Thioredoxin PF00085.15 CEP18291.1 - 1.7e-65 217.2 2.0 1.8e-35 120.7 0.1 4.4 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CEP18291.1 - 4.8e-47 160.1 3.6 1.7e-32 112.7 0.8 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CEP18291.1 - 1.5e-11 44.4 3.2 1.9e-05 24.8 0.1 4.7 3 2 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEP18291.1 - 1.1e-10 41.4 1.3 0.00071 19.6 0.0 5.2 4 2 2 6 6 6 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CEP18291.1 - 2e-10 40.5 0.1 0.00058 19.8 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.8 CEP18291.1 - 8.9e-07 28.8 0.3 0.22 11.4 0.0 4.0 4 0 0 4 4 4 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 CEP18291.1 - 0.00013 21.6 0.0 0.02 14.7 0.1 3.1 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_9 PF14595.1 CEP18291.1 - 0.0011 18.4 0.1 1.7 8.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.16 CEP18291.1 - 0.011 15.4 0.6 3.5 7.3 0.0 3.0 3 0 0 3 3 3 0 AhpC/TSA family HyaE PF07449.6 CEP18291.1 - 0.074 12.9 0.1 4.2 7.3 0.0 3.5 3 1 0 3 3 3 0 Hydrogenase-1 expression protein HyaE DSBA PF01323.15 CEP18291.1 - 0.09 12.3 1.0 9.5 5.7 0.0 3.4 3 1 1 4 4 4 0 DSBA-like thioredoxin domain CorA PF01544.13 CEP18292.1 - 1.6e-45 155.4 6.4 3.3e-45 154.3 4.4 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein GFO_IDH_MocA PF01408.17 CEP18293.1 - 1.9e-28 99.3 0.2 3.3e-28 98.6 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 CEP18293.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CEP18293.1 - 5.6e-06 26.4 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 CEP18293.1 - 1.2e-05 25.5 0.1 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 CEP18293.1 - 0.00049 20.4 0.0 0.00098 19.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CEP18293.1 - 0.008 15.3 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF613 PF04764.7 CEP18293.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF613) IlvN PF07991.7 CEP18293.1 - 0.043 13.1 0.1 0.099 12.0 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CEP18293.1 - 0.074 12.8 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase BTG PF07742.7 CEP18294.1 - 1e-32 112.1 0.0 1.3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 BTG family ECH PF00378.15 CEP18295.1 - 1.1e-48 165.5 0.1 1.3e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CEP18295.1 - 0.0048 16.6 0.4 0.43 10.3 0.0 2.3 1 1 0 2 2 2 2 Peptidase family S49 Peptidase_M3 PF01432.15 CEP18296.1 - 1.3e-140 469.5 1.9 1.9e-140 468.9 1.3 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 CEP18296.1 - 0.036 14.1 0.3 0.092 12.8 0.2 1.6 1 0 0 1 1 1 0 Effector protein GDPD PF03009.12 CEP18296.1 - 0.1 12.0 1.6 0.24 10.8 1.0 1.6 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Peptidase_C1_2 PF03051.10 CEP18297.1 - 3.5e-164 546.4 0.3 4.3e-164 546.2 0.2 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CEP18297.1 - 5.6e-05 23.1 0.1 0.075 12.8 0.1 2.6 2 0 0 2 2 2 2 Papain family cysteine protease GFO_IDH_MocA PF01408.17 CEP18298.1 - 1.2e-26 93.5 0.0 2.1e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CEP18298.1 - 3.8e-15 55.6 0.0 6.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 CEP18298.1 - 3.2e-05 24.2 0.0 6.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 CEP18298.1 - 5.3e-05 23.5 0.0 9.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 CEP18298.1 - 0.0024 18.3 0.0 0.0054 17.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain WD40 PF00400.27 CEP18299.1 - 1.5e-26 91.2 10.7 1.6e-09 37.3 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat HIG_1_N PF04588.8 CEP18300.1 - 2.5e-19 68.7 3.0 2.8e-19 68.6 1.4 1.6 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF2681 PF10883.3 CEP18300.1 - 2 8.6 7.4 0.096 12.9 1.2 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) FAM165 PF14981.1 CEP18300.1 - 4.4 6.8 9.0 0.19 11.2 1.3 2.2 2 1 0 2 2 2 0 FAM165 family MaoC_dehydratas PF01575.14 CEP18301.1 - 9.6e-28 96.0 0.0 1.6e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CEP18301.1 - 7e-08 32.3 0.0 3.9e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NUDIX PF00293.23 CEP18302.1 - 1.5e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Arrestin_N PF00339.24 CEP18303.1 - 9e-12 45.0 0.1 2.5e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Homeobox PF00046.24 CEP18304.1 - 2.2e-21 75.2 1.1 4.9e-21 74.1 0.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP18304.1 - 0.0032 17.1 0.2 0.0083 15.8 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain MFS_1 PF07690.11 CEP18305.1 - 4.9e-20 71.5 42.3 1.2e-11 43.9 15.4 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 CEP18305.1 - 1.2e-08 34.6 3.4 3.8e-08 33.0 2.3 2.0 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.11 CEP18305.1 - 1.1e-07 31.0 9.3 1.1e-07 31.0 6.5 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.14 CEP18305.1 - 4.6e-05 22.1 11.0 4.6e-05 22.1 7.6 2.9 2 1 0 2 2 2 1 LacY proton/sugar symporter DUF3814 PF12769.2 CEP18305.1 - 0.0091 16.1 2.2 0.0091 16.1 1.5 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3814) TPR_16 PF13432.1 CEP18307.1 - 6.9e-18 64.8 30.5 0.00058 20.4 1.3 8.2 5 3 2 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 CEP18307.1 - 3.7e-15 56.0 47.5 0.00018 21.7 1.5 9.0 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 CEP18307.1 - 4.6e-15 54.7 24.9 0.06 14.0 0.0 11.0 8 3 4 12 12 12 4 Tetratricopeptide repeat SRP72 PF08492.7 CEP18307.1 - 1.3e-13 51.0 5.6 1.3e-13 51.0 3.9 3.1 3 0 0 3 3 1 1 SRP72 RNA-binding domain TPR_11 PF13414.1 CEP18307.1 - 1.6e-13 50.0 26.3 0.0019 17.7 0.1 7.7 7 0 0 7 7 7 4 TPR repeat TPR_2 PF07719.12 CEP18307.1 - 2.2e-12 45.8 23.3 0.0088 15.8 0.1 10.0 11 0 0 11 11 10 3 Tetratricopeptide repeat Apc3 PF12895.2 CEP18307.1 - 6.9e-10 38.9 35.4 1.6e-06 28.1 2.2 6.9 2 2 6 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CEP18307.1 - 4e-09 36.3 34.1 0.022 15.2 0.3 9.8 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEP18307.1 - 1.7e-07 31.0 27.6 5.3e-05 23.0 2.4 6.7 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEP18307.1 - 7.7e-07 28.8 14.6 1.3 9.3 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 CEP18307.1 - 7.8e-07 28.4 32.0 2.5e-05 23.4 3.6 5.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 CEP18307.1 - 1.6e-06 27.9 0.2 4.1 8.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP18307.1 - 4.8e-06 25.9 15.1 0.34 10.7 0.1 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP18307.1 - 8.6e-05 21.9 21.0 0.58 9.8 0.1 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP18307.1 - 0.00039 19.9 25.4 0.43 10.4 0.1 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEP18307.1 - 0.00051 19.8 19.6 6.6 6.6 0.0 7.4 7 1 1 8 8 7 2 Tetratricopeptide repeat PPR PF01535.15 CEP18307.1 - 0.013 15.4 0.0 69 3.7 0.0 4.6 5 0 0 5 5 4 0 PPR repeat BTAD PF03704.12 CEP18307.1 - 0.026 14.8 0.1 0.026 14.8 0.0 4.9 4 2 1 5 5 5 0 Bacterial transcriptional activator domain TPR_3 PF07720.7 CEP18307.1 - 0.049 13.4 8.7 3.6 7.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEP18307.1 - 0.12 12.3 11.1 8.6 6.4 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.14 CEP18307.1 - 0.16 11.9 5.1 8.8 6.3 0.1 3.6 2 1 1 3 3 3 0 Ribosomal protein L22p/L17e Formyl_trans_N PF00551.14 CEP18308.1 - 4e-50 169.8 0.1 5e-50 169.5 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase DUF1640 PF07798.6 CEP18311.1 - 2.3e-19 70.0 10.1 3.4e-19 69.5 7.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Chordopox_G3 PF06129.7 CEP18311.1 - 0.0063 16.6 2.7 0.0063 16.6 1.9 2.1 2 0 0 2 2 2 1 Chordopoxvirus G3 protein DUF2951 PF11166.3 CEP18311.1 - 0.022 14.5 8.4 0.48 10.2 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) AKNA PF12443.3 CEP18311.1 - 0.091 12.7 8.5 0.047 13.7 2.8 2.5 1 1 2 3 3 3 0 AT-hook-containing transcription factor GlnD_UR_UTase PF08335.6 CEP18311.1 - 0.25 11.1 3.3 1.1 9.1 2.4 2.0 1 1 0 1 1 1 0 GlnD PII-uridylyltransferase 5_nucleotid PF05761.9 CEP18311.1 - 0.8 8.1 6.7 0.16 10.4 2.5 1.4 2 0 0 2 2 2 0 5' nucleotidase family Apolipoprotein PF01442.13 CEP18311.1 - 1.5 8.2 12.1 2.8 7.3 7.6 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Gtr1_RagA PF04670.7 CEP18312.1 - 1.8e-102 341.3 0.3 2.2e-102 341.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CEP18312.1 - 2.5e-09 36.5 0.1 4.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CEP18312.1 - 2.5e-08 33.4 0.0 4.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP18312.1 - 3.1e-06 27.6 0.1 1.3e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CEP18312.1 - 1.6e-05 24.8 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP18312.1 - 0.00036 20.0 0.0 0.00056 19.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CEP18312.1 - 0.0033 17.7 0.3 0.0059 16.9 0.2 1.7 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.5 CEP18312.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CEP18312.1 - 0.026 13.9 0.3 0.14 11.6 0.0 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 CEP18312.1 - 0.042 12.7 0.4 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 CEP18312.1 - 0.046 13.2 0.5 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_S18 PF01084.15 CEP18313.1 - 7.4e-23 80.1 0.1 1.5e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 GDI PF00996.13 CEP18314.1 - 5.3e-195 647.8 0.3 6.1e-195 647.6 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF4351 PF14261.1 CEP18314.1 - 0.014 15.2 0.0 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) DAO PF01266.19 CEP18314.1 - 0.017 14.0 0.0 0.031 13.1 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase IMS PF00817.15 CEP18316.1 - 1.1e-38 132.3 0.1 3.3e-38 130.8 0.1 1.9 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CEP18316.1 - 3.1e-19 69.1 0.5 8.4e-19 67.7 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CEP18316.1 - 5.8e-06 26.0 0.0 2.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif DUF4414 PF14377.1 CEP18316.1 - 6.8e-06 25.9 6.9 0.02 14.7 0.2 3.9 2 1 1 3 3 3 3 Domain of unknown function (DUF4414) PTCB-BRCT PF12738.2 CEP18316.1 - 0.00024 20.9 0.0 0.00062 19.5 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CEP18316.1 - 0.0064 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Cdd1 PF11731.3 CEP18316.1 - 0.015 15.2 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus Pox_A11 PF05061.8 CEP18316.1 - 0.024 13.7 0.2 0.063 12.3 0.2 1.7 1 0 0 1 1 1 0 Poxvirus A11 Protein HHH_5 PF14520.1 CEP18316.1 - 0.044 13.9 0.1 0.36 11.0 0.1 2.4 1 1 0 1 1 1 0 Helix-hairpin-helix domain DUF3661 PF12400.3 CEP18317.1 - 2.3e-41 140.8 10.9 3.5e-41 140.3 7.5 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein BAF1_ABF1 PF04684.8 CEP18318.1 - 0.068 12.0 3.0 0.11 11.3 2.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RNA_pol_Rpc34 PF05158.7 CEP18320.1 - 6e-87 291.8 0.1 7.1e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit SMC_Nse1 PF07574.8 CEP18320.1 - 0.0019 17.8 0.1 0.0038 16.8 0.1 1.6 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex B-block_TFIIIC PF04182.7 CEP18320.1 - 0.0027 17.5 0.3 0.011 15.5 0.1 1.9 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC RPA_C PF08784.6 CEP18320.1 - 0.0095 16.3 0.2 0.18 12.2 0.1 2.5 3 0 0 3 3 3 1 Replication protein A C terminal HTH_36 PF13730.1 CEP18320.1 - 0.024 14.7 1.3 0.038 14.1 0.4 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.27 CEP18323.1 - 1e-27 94.9 11.3 3.5e-08 33.0 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 CEP18323.1 - 9.3e-05 22.3 4.9 0.00019 21.3 1.6 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) BBS2_Mid PF14783.1 CEP18323.1 - 0.031 14.0 0.2 0.19 11.5 0.1 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DDE_3 PF13358.1 CEP18324.1 - 5.5e-15 55.3 0.0 1.8e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF1804 PF08822.6 CEP18324.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_23 PF13384.1 CEP18324.1 - 0.0094 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP18324.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.1 CEP18324.1 - 0.061 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SWIM PF04434.12 CEP18328.1 - 0.0069 15.8 1.9 0.015 14.7 1.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger PNP_UDP_1 PF01048.15 CEP18329.1 - 1.8e-42 144.9 1.4 2.7e-42 144.3 1.0 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily p450 PF00067.17 CEP18330.1 - 5e-81 272.5 0.0 6.3e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHO_dh PF01180.16 CEP18331.1 - 3.7e-63 213.2 0.0 4.3e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Beach PF02138.13 CEP18332.1 - 3.6e-61 206.9 0.0 8.7e-61 205.7 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 CEP18332.1 - 2e-12 46.4 7.1 4.4e-07 29.5 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase PF00069.20 CEP18332.1 - 3.9e-07 29.4 0.1 2.6e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 CEP18332.1 - 0.0005 19.1 0.0 0.00098 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like LAB_N PF07578.6 CEP18335.1 - 0.096 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Methyltransf_12 PF08242.7 CEP18336.1 - 8.4e-28 96.7 0.0 5.4e-14 52.4 0.0 3.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 CEP18336.1 - 3.8e-27 94.9 0.0 4e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CEP18336.1 - 3.9e-18 65.7 0.0 1.4e-09 38.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CEP18336.1 - 3e-15 56.1 0.1 8.9e-09 35.1 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 CEP18336.1 - 1.8e-13 50.6 0.0 1.3e-07 31.8 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 CEP18336.1 - 1e-12 48.6 0.0 2.4e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain DUF3419 PF11899.3 CEP18336.1 - 7.9e-10 37.9 0.0 0.00076 18.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3419) NNMT_PNMT_TEMT PF01234.12 CEP18336.1 - 7.2e-08 31.7 0.0 0.36 9.7 0.1 3.3 2 1 1 3 3 3 3 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 CEP18336.1 - 1.4e-07 31.5 0.0 8e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 CEP18336.1 - 5.1e-07 29.2 0.0 0.011 15.1 0.0 2.5 2 1 0 2 2 2 2 Nodulation protein S (NodS) MTS PF05175.9 CEP18336.1 - 8.7e-07 28.4 0.0 0.00058 19.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain TehB PF03848.9 CEP18336.1 - 1.2e-06 27.8 0.0 0.0016 17.6 0.0 2.6 2 0 0 2 2 2 2 Tellurite resistance protein TehB CMAS PF02353.15 CEP18336.1 - 2.1e-05 23.7 0.0 0.013 14.6 0.0 2.3 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase CheR PF01739.13 CEP18336.1 - 2.7e-05 23.5 0.0 1.8 7.8 0.0 3.6 3 0 0 3 3 3 2 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.1 CEP18336.1 - 4.3e-05 24.3 0.0 0.1 13.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.8 CEP18336.1 - 4.5e-05 22.7 0.0 0.092 11.8 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) FdhE PF04216.7 CEP18336.1 - 0.00046 19.9 0.0 0.04 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein involved in formate dehydrogenase formation DUF3298 PF11738.3 CEP18336.1 - 0.0077 16.7 4.5 5 7.7 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3298) Rsm22 PF09243.5 CEP18336.1 - 0.013 14.5 0.0 3.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 DUF3139 PF11337.3 CEP18336.1 - 0.071 13.4 1.3 72 3.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) MIR PF02815.14 CEP18337.1 - 1.1e-29 103.3 0.8 1.6e-29 102.8 0.5 1.2 1 0 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.6 CEP18337.1 - 0.13 11.2 0.7 0.41 9.6 0.5 1.8 1 1 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor LigA PF07746.6 CEP18338.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit CKS PF01111.14 CEP18340.1 - 4.5e-28 96.8 1.6 1e-27 95.7 1.1 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit V-SNARE PF05008.10 CEP18341.1 - 0.009 16.1 0.8 0.037 14.2 0.1 2.0 1 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus DUF3919 PF13057.1 CEP18341.1 - 0.017 14.6 1.5 0.017 14.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Sec34 PF04136.10 CEP18341.1 - 0.018 14.7 0.6 0.048 13.3 0.4 1.6 1 1 0 1 1 1 0 Sec34-like family DUF1741 PF08427.5 CEP18341.1 - 0.035 13.5 0.1 0.042 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DUF1311 PF07007.7 CEP18341.1 - 0.063 13.3 1.1 0.1 12.7 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1311) DUF1664 PF07889.7 CEP18341.1 - 0.079 12.7 1.1 0.2 11.4 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4631 PF15450.1 CEP18341.1 - 0.084 11.1 2.3 0.11 10.8 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) Ada3 PF10198.4 CEP18341.1 - 0.15 11.8 4.1 0.59 9.8 2.4 2.0 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 Fzo_mitofusin PF04799.8 CEP18341.1 - 0.19 11.0 1.8 0.3 10.4 0.4 1.7 1 1 1 2 2 2 0 fzo-like conserved region Syntaxin-6_N PF09177.6 CEP18341.1 - 0.29 11.5 2.2 1.8 8.9 0.8 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3592 PF12158.3 CEP18342.1 - 0.073 12.8 0.6 0.13 12.0 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) DUF912 PF06024.7 CEP18342.1 - 0.24 11.4 3.2 1.8 8.6 2.1 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DDE_3 PF13358.1 CEP18343.1 - 2e-06 27.6 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MIR PF02815.14 CEP18344.1 - 4.5e-25 88.2 1.5 8.7e-25 87.3 1.0 1.5 1 1 0 1 1 1 1 MIR domain PIF1 PF05970.9 CEP18344.1 - 1.4e-12 47.2 0.0 2.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Chitin_bind_3 PF03067.10 CEP18344.1 - 0.027 14.7 0.3 0.037 14.2 0.2 1.3 1 0 0 1 1 1 0 Chitin binding domain Response_reg PF00072.19 CEP18345.1 - 1.2e-26 92.9 0.5 3.6e-26 91.3 0.3 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HSF_DNA-bind PF00447.12 CEP18345.1 - 2e-18 66.4 3.7 2e-18 66.4 2.6 3.1 2 1 1 3 3 3 1 HSF-type DNA-binding YhjQ PF06564.7 CEP18345.1 - 0.0059 15.9 3.9 0.09 12.1 2.3 2.6 2 0 0 2 2 2 1 YhjQ protein Otopetrin PF03189.8 CEP18345.1 - 1.1 8.1 7.5 0.043 12.8 0.6 1.9 2 0 0 2 2 2 0 Otopetrin Actin PF00022.14 CEP18346.1 - 7.1e-140 465.8 0.0 8.7e-140 465.5 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CEP18346.1 - 5.4e-05 21.9 0.0 0.26 9.8 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein CPSF100_C PF13299.1 CEP18346.1 - 0.0096 16.1 2.0 0.072 13.2 0.1 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal LON PF02190.11 CEP18346.1 - 2.8 7.5 6.3 14 5.2 4.4 1.9 1 1 0 1 1 1 0 ATP-dependent protease La (LON) domain S-antigen PF05756.6 CEP18346.1 - 3.2 7.7 7.1 8.8 6.3 4.9 1.7 1 0 0 1 1 1 0 S-antigen protein HMGL-like PF00682.14 CEP18347.1 - 4e-80 268.8 0.2 2.3e-79 266.3 0.0 2.2 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.5 CEP18347.1 - 8.4e-21 74.1 3.0 1.4e-20 73.3 2.1 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF533 PF04391.7 CEP18347.1 - 0.0071 15.7 0.1 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF533) Kinetochor_Ybp2 PF08568.5 CEP18348.1 - 8.1e-21 73.9 9.3 3.2e-19 68.6 6.5 2.7 1 1 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-TFIIB PF13453.1 CEP18348.1 - 0.0095 15.1 0.8 0.022 13.9 0.6 1.7 1 0 0 1 1 1 1 Transcription factor zinc-finger HEAT_2 PF13646.1 CEP18348.1 - 0.057 13.6 0.0 8.4 6.7 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats Ham1p_like PF01725.11 CEP18349.1 - 7.2e-54 182.0 0.0 8.3e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SLS PF14611.1 CEP18349.1 - 0.05 13.0 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator APH PF01636.18 CEP18350.1 - 1.4e-40 139.5 0.0 1.9e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CEP18350.1 - 4.1e-06 26.1 0.0 4.7e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 CEP18350.1 - 0.00081 18.4 0.0 0.012 14.6 0.0 2.2 1 1 1 2 2 2 1 Fructosamine kinase RIO1 PF01163.17 CEP18350.1 - 0.0014 17.9 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 CEP18350.1 - 0.013 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ni_hydr_CYTB PF01292.15 CEP18351.1 - 0.042 13.2 0.8 0.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Arm PF00514.18 CEP18352.1 - 7.3e-70 228.6 23.9 6.3e-12 44.8 0.1 10.3 10 0 0 10 10 10 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEP18352.1 - 6.3e-27 93.6 12.9 3.3e-06 27.2 0.2 6.8 2 2 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 CEP18352.1 - 4.7e-16 58.7 14.2 0.037 14.5 0.0 8.6 7 1 2 9 9 9 6 HEAT-like repeat HEAT PF02985.17 CEP18352.1 - 1e-14 53.1 17.3 0.1 12.7 0.0 9.1 9 0 0 9 9 9 4 HEAT repeat Adaptin_N PF01602.15 CEP18352.1 - 2.2e-13 49.3 13.7 1.8e-10 39.7 1.3 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 CEP18352.1 - 4.4e-10 39.1 8.0 0.011 14.9 1.5 3.7 1 1 2 3 3 3 3 Armadillo-like KAP PF05804.7 CEP18352.1 - 3.4e-09 35.2 3.0 4.9e-09 34.6 2.1 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 CEP18352.1 - 3.4e-07 29.6 7.3 0.00096 18.3 0.2 3.3 1 1 2 3 3 3 3 V-ATPase subunit H Cnd1 PF12717.2 CEP18352.1 - 8.4e-06 25.7 7.7 0.00055 19.8 1.2 3.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CEP18352.1 - 0.00035 20.9 1.1 0.83 10.0 0.2 3.9 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 CEP18352.1 - 0.013 15.4 10.9 1.9 8.4 0.1 4.8 3 1 3 6 6 6 0 V-ATPase subunit H HEAT_PBS PF03130.11 CEP18352.1 - 0.013 15.8 12.1 33 5.3 0.0 7.9 8 1 0 8 8 7 0 PBS lyase HEAT-like repeat DUF4193 PF13834.1 CEP18353.1 - 7.8e-05 22.7 0.8 0.00011 22.2 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) FAM176 PF14851.1 CEP18353.1 - 0.0008 19.1 2.8 0.0011 18.6 2.0 1.2 1 0 0 1 1 1 1 FAM176 family DUF2956 PF11169.3 CEP18353.1 - 0.0055 16.6 8.5 0.0055 16.6 5.9 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF2956) DUF1168 PF06658.7 CEP18353.1 - 0.0059 16.1 13.6 0.0099 15.3 9.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) BLVR PF06375.6 CEP18353.1 - 0.011 15.6 14.7 0.011 15.6 10.2 1.4 2 0 0 2 2 1 0 Bovine leukaemia virus receptor (BLVR) AIF_C PF14721.1 CEP18353.1 - 0.029 14.5 1.5 0.044 14.0 1.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PBP1_TM PF14812.1 CEP18353.1 - 0.033 14.4 7.6 0.064 13.5 5.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 CEP18353.1 - 0.044 12.5 7.8 0.053 12.2 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3451 PF11933.3 CEP18353.1 - 0.051 13.3 6.7 0.067 12.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Pox_Ag35 PF03286.9 CEP18353.1 - 0.06 12.8 12.8 0.092 12.2 8.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_60s PF00428.14 CEP18353.1 - 0.066 13.6 6.6 0.1 12.9 4.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein FLO_LFY PF01698.11 CEP18353.1 - 0.083 11.7 8.5 0.092 11.5 5.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein BSP_II PF05432.6 CEP18353.1 - 0.089 12.0 7.6 0.12 11.6 5.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NARP1 PF12569.3 CEP18353.1 - 0.094 11.4 9.0 0.1 11.3 6.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 CEP18353.1 - 0.11 11.7 10.2 0.15 11.2 7.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger RNA_pol_3_Rpc31 PF11705.3 CEP18353.1 - 0.13 12.1 7.8 0.18 11.7 5.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1682 PF07946.9 CEP18353.1 - 0.19 10.5 11.4 0.2 10.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4366 PF14283.1 CEP18353.1 - 0.21 10.9 5.2 0.31 10.4 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) GAGA_bind PF06217.7 CEP18353.1 - 0.25 11.2 6.3 0.26 11.1 4.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family OAD_gamma PF04277.8 CEP18353.1 - 0.25 11.7 5.0 0.44 10.9 3.4 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Eapp_C PF10238.4 CEP18353.1 - 0.25 11.2 6.4 0.42 10.5 4.4 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF3464 PF11947.3 CEP18353.1 - 0.26 10.7 2.2 0.33 10.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Anoctamin PF04547.7 CEP18353.1 - 0.29 9.7 1.5 0.3 9.6 1.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Spore_coat_CotO PF14153.1 CEP18353.1 - 0.29 10.5 11.3 0.44 9.9 7.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO S-antigen PF05756.6 CEP18353.1 - 0.35 10.8 10.5 0.26 11.3 6.3 1.5 1 1 1 2 2 2 0 S-antigen protein Vfa1 PF08432.5 CEP18353.1 - 0.52 10.2 15.1 0.85 9.6 10.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 CEP18353.1 - 0.57 9.9 4.1 0.62 9.8 2.8 1.2 1 0 0 1 1 1 0 DDHD domain Peptidase_S49_N PF08496.5 CEP18353.1 - 0.66 9.7 14.3 0.47 10.2 9.2 1.3 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF3868 PF12984.2 CEP18353.1 - 0.67 9.4 3.2 1.2 8.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) DUF2897 PF11446.3 CEP18353.1 - 0.84 9.5 8.6 2 8.3 6.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Arrestin_N PF00339.24 CEP18353.1 - 1 9.1 6.6 0.93 9.2 4.0 1.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Neur_chan_memb PF02932.11 CEP18353.1 - 1.1 9.1 3.8 1.4 8.7 2.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 CEP18353.1 - 1.2 8.5 16.8 1.9 7.9 11.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1754 PF08555.5 CEP18353.1 - 1.2 9.7 22.2 0.15 12.6 11.8 1.9 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PBP_sp32 PF07222.7 CEP18353.1 - 2.6 7.1 8.7 3.4 6.7 6.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3899 PF13038.1 CEP18353.1 - 3.5 7.8 6.6 1.6 8.9 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) YqfQ PF14181.1 CEP18353.1 - 4.4 7.3 10.8 6.8 6.7 7.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein Bap31 PF05529.7 CEP18353.1 - 4.7 6.6 7.3 6.3 6.1 5.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3987 PF13148.1 CEP18353.1 - 6.6 5.1 9.6 8.4 4.8 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Mito_carr PF00153.22 CEP18354.1 - 2e-63 210.1 3.2 7.9e-21 73.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.3 CEP18354.1 - 0.0084 15.8 0.3 3.2 7.5 0.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3764) Nucleoplasmin PF03066.10 CEP18355.1 - 0.54 9.7 9.8 0.032 13.7 2.3 2.2 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CEP18355.1 - 5.2 7.3 13.7 0.51 10.5 5.8 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HMG_box PF00505.14 CEP18356.1 - 6.8e-18 64.7 4.0 6.8e-18 64.7 2.8 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP18356.1 - 1.9e-10 40.9 3.4 1.9e-10 40.9 2.4 1.9 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.7 CEP18356.1 - 0.0013 18.3 0.1 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain Tol_Tol_Ttg2 PF05494.7 CEP18356.1 - 0.016 14.8 0.6 0.024 14.2 0.4 1.3 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 Elongin_A PF06881.6 CEP18356.1 - 0.027 14.8 5.2 0.05 13.9 3.6 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A FancD2 PF14631.1 CEP18356.1 - 2.7 4.9 6.2 2.9 4.8 4.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease HTH_29 PF13551.1 CEP18357.1 - 7.1e-10 39.0 0.0 9.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 CEP18357.1 - 3.5e-08 34.1 0.0 5.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP18357.1 - 0.00026 20.9 0.1 0.00082 19.3 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP18357.1 - 0.0026 17.3 0.0 0.061 12.9 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 CEP18357.1 - 0.026 14.4 0.1 6.3 6.8 0.1 2.2 1 1 1 2 2 2 0 Transposase MKT1_C PF12246.3 CEP18358.1 - 0.13 11.2 0.1 0.58 9.1 0.0 1.7 1 1 1 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication RVT_1 PF00078.22 CEP18359.1 - 1.1e-27 96.8 0.0 1.9e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4174 PF13778.1 CEP18359.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) RFPL3_antisense PF10489.4 CEP18361.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense Nuc_sug_transp PF04142.10 CEP18362.1 - 1.1e-09 37.7 3.0 1.6e-09 37.2 1.9 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CEP18362.1 - 8.7e-09 34.7 12.4 1.4e-08 34.0 8.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP18362.1 - 8.8e-07 29.0 21.5 3.4e-05 23.8 2.8 2.9 2 1 0 2 2 2 2 EamA-like transporter family Bax1-I PF01027.15 CEP18362.1 - 0.0013 18.3 7.1 0.0013 18.3 4.9 2.9 1 1 1 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 TPT PF03151.11 CEP18362.1 - 0.0034 17.0 9.1 0.0034 17.0 6.3 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF914 PF06027.7 CEP18362.1 - 0.007 15.2 12.4 0.023 13.5 8.6 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) GIIM PF08388.6 CEP18363.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Pkinase PF00069.20 CEP18364.1 - 2.3e-71 240.0 0.0 2.3e-71 240.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18364.1 - 1.7e-48 164.9 0.0 5.2e-48 163.3 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CEP18364.1 - 5.1e-22 78.0 1.5 4.7e-21 74.9 0.0 3.5 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 CEP18364.1 - 6.7e-06 25.2 0.0 1.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 CEP18364.1 - 0.03 13.5 0.0 0.03 13.5 0.0 3.0 4 0 0 4 4 4 0 DSHCT (NUC185) domain C2 PF00168.25 CEP18365.1 - 2.6e-81 267.5 3.3 1.2e-18 66.7 0.1 6.4 6 0 0 6 6 6 6 C2 domain RICTOR_phospho PF14665.1 CEP18367.1 - 0.076 13.1 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Levi_coat PF01819.12 CEP18368.1 - 0.082 12.4 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Levivirus coat protein HLH PF00010.21 CEP18369.1 - 3.4e-10 39.4 0.1 1.4e-09 37.4 0.1 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Blo-t-5 PF11642.3 CEP18369.1 - 0.0086 15.8 5.6 0.99 9.1 0.0 2.5 2 0 0 2 2 2 2 Mite allergen Blo t 5 PIF1 PF05970.9 CEP18372.1 - 8.2e-19 67.7 0.0 1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 CEP18372.1 - 2.8e-05 23.7 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CEP18372.1 - 0.00035 20.2 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP18372.1 - 0.00063 19.7 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CEP18372.1 - 0.0041 17.9 0.0 0.01 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CEP18372.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP18372.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 CEP18372.1 - 0.029 12.9 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 CEP18372.1 - 0.032 13.2 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 CEP18372.1 - 0.049 12.5 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 CEP18372.1 - 0.062 12.7 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 CEP18372.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 CEP18372.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 CEP18373.1 - 1.9e-32 112.6 0.0 2e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase DUF2681 PF10883.3 CEP18374.1 - 1.1 9.5 12.5 0.4 10.9 0.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Vps16_N PF04841.8 CEP18375.1 - 1.7e-106 356.2 0.0 2.3e-106 355.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 CEP18375.1 - 1e-95 320.3 3.3 1.8e-95 319.5 2.3 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region ODR4-like PF14778.1 CEP18375.1 - 0.006 15.3 0.4 0.0099 14.6 0.3 1.2 1 0 0 1 1 1 1 Olfactory receptor 4-like DUF1476 PF07345.6 CEP18375.1 - 0.02 15.1 2.4 0.087 13.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1476) lci PF12197.3 CEP18375.1 - 0.1 12.2 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein Golgin_A5 PF09787.4 CEP18375.1 - 0.14 10.6 2.0 0.43 9.0 0.5 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 Nucleoporin_N PF08801.6 CEP18376.1 - 1.1e-43 149.5 5.6 1.8e-43 148.9 3.9 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 CEP18376.1 - 3.3e-33 115.0 2.3 6.9e-33 114.0 1.6 1.4 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal TPR_7 PF13176.1 CEP18376.1 - 0.0036 16.9 0.4 0.014 15.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP18376.1 - 0.026 14.4 0.1 0.099 12.6 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP18376.1 - 0.053 13.4 0.5 0.17 11.9 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 CEP18376.1 - 0.084 13.2 0.0 0.35 11.2 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S13 PF00416.17 CEP18377.1 - 2.4e-38 130.8 1.4 2.9e-38 130.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CEP18377.1 - 0.0054 15.3 0.0 0.0056 15.2 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 CEP18377.1 - 0.04 12.7 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DPPIV_N PF00930.16 CEP18378.1 - 1.2e-100 336.5 7.7 1.9e-100 335.8 5.4 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CEP18378.1 - 2.6e-42 144.4 1.7 4.3e-42 143.7 1.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEP18378.1 - 3.3e-06 26.9 0.1 6.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP18378.1 - 0.00037 20.4 0.1 0.0007 19.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CEP18378.1 - 0.00048 19.6 0.4 0.001 18.5 0.3 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF4367 PF14285.1 CEP18378.1 - 0.2 10.9 2.3 0.5 9.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Ion_trans PF00520.26 CEP18379.1 - 2.5e-05 23.6 4.2 2.5e-05 23.6 2.9 1.7 1 1 1 2 2 2 1 Ion transport protein PKD_channel PF08016.7 CEP18379.1 - 0.00011 20.8 2.3 0.00015 20.3 1.6 1.2 1 0 0 1 1 1 1 Polycystin cation channel CbiQ PF02361.11 CEP18379.1 - 0.1 12.1 4.1 0.14 11.7 2.8 1.1 1 0 0 1 1 1 0 Cobalt transport protein DnaJ PF00226.26 CEP18380.1 - 4.5e-20 71.1 1.2 1.6e-19 69.3 0.8 2.0 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 CEP18381.1 - 0.023 13.8 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Cas_Cas4 PF01930.12 CEP18382.1 - 0.011 15.6 0.2 0.038 13.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF83 SNF2_N PF00176.18 CEP18383.1 - 3.8e-67 226.1 1.5 5.5e-67 225.6 0.3 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEP18383.1 - 3.4e-09 36.4 0.0 8.9e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP18383.1 - 7.6e-08 32.3 0.3 1.6e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEP18383.1 - 6.2e-07 29.0 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 CEP18383.1 - 0.0002 21.3 13.7 0.0002 21.3 9.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP18383.1 - 0.00057 19.4 13.4 0.00057 19.4 9.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP18383.1 - 0.0007 19.2 11.6 0.0007 19.2 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP18383.1 - 0.0019 17.9 12.6 0.0019 17.9 8.7 2.2 2 0 0 2 2 2 1 Ring finger domain FlhC PF05280.6 CEP18383.1 - 0.075 12.5 2.3 6.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) FUSC PF04632.7 CEP18388.1 - 0.047 12.1 2.5 0.073 11.5 1.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family V-ATPase_G PF03179.10 CEP18389.1 - 7.7e-30 103.3 16.9 8.7e-30 103.1 11.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit M20_dimer PF07687.9 CEP18389.1 - 0.057 13.1 0.6 0.19 11.4 0.0 2.0 1 1 1 2 2 2 0 Peptidase dimerisation domain Strumpellin PF10266.4 CEP18389.1 - 0.058 10.8 5.4 0.068 10.5 3.8 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin TBPIP PF07106.8 CEP18389.1 - 0.068 12.7 10.1 0.082 12.4 7.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2115 PF09888.4 CEP18389.1 - 0.097 12.7 5.7 0.12 12.5 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) ATP-synt_B PF00430.13 CEP18389.1 - 0.36 10.6 21.6 0.033 13.9 6.7 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF883 PF05957.8 CEP18389.1 - 0.73 10.2 12.4 0.51 10.7 1.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Seryl_tRNA_N PF02403.17 CEP18389.1 - 0.77 9.7 13.7 1.9 8.5 9.5 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Striatin PF08232.7 CEP18389.1 - 1.2 9.4 11.5 1.4 9.1 8.0 1.1 1 0 0 1 1 1 0 Striatin family HAUS6_N PF14661.1 CEP18389.1 - 1.4 8.2 10.4 1.6 8.0 7.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Nop25 PF09805.4 CEP18389.1 - 2.1 8.4 14.7 2.8 7.9 10.2 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4407 PF14362.1 CEP18389.1 - 3.3 6.5 9.8 5.3 5.8 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PEP-utilisers_N PF05524.8 CEP18389.1 - 3.4 7.4 10.2 25 4.6 7.1 2.0 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal CENP-H PF05837.7 CEP18389.1 - 4.3 7.5 13.9 16 5.6 9.5 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Atg14 PF10186.4 CEP18389.1 - 4.7 6.0 11.3 5.7 5.7 7.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Caudo_TAP PF02413.12 CEP18389.1 - 5.4 7.1 13.3 13 5.9 2.4 2.1 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein GvpO PF05800.6 CEP18389.1 - 5.8 6.8 8.5 4.4 7.2 0.7 2.1 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpO IncA PF04156.9 CEP18389.1 - 7.5 6.1 8.8 12 5.4 6.1 1.4 1 1 0 1 1 1 0 IncA protein Ribosomal_L3 PF00297.17 CEP18390.1 - 1.9e-120 401.2 7.7 2.2e-120 400.9 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PSP1 PF04468.7 CEP18391.1 - 1e-30 105.5 4.2 1e-30 105.5 2.9 2.2 2 0 0 2 2 2 1 PSP1 C-terminal conserved region DUF1900 PF08954.6 CEP18391.1 - 0.026 14.0 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) ATP-synt_G PF04718.10 CEP18391.1 - 0.36 11.4 5.9 0.12 13.0 1.3 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Gpi1 PF05024.10 CEP18392.1 - 5.6e-63 212.0 12.5 5.6e-63 212.0 8.6 2.2 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) MUG113 PF13455.1 CEP18393.1 - 8.1e-17 61.4 0.0 1.6e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 CEP18393.1 - 3.5e-14 53.0 0.0 1.1e-13 51.4 0.0 1.8 1 1 0 1 1 1 1 T5orf172 domain Pro_dh PF01619.13 CEP18394.1 - 1.9e-59 201.2 7.3 3.2e-59 200.4 5.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase OrfB_Zn_ribbon PF07282.6 CEP18395.1 - 0.025 14.2 0.9 0.054 13.1 0.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Neur_chan_memb PF02932.11 CEP18395.1 - 0.77 9.5 3.9 0.27 11.0 0.5 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.11 CEP18396.1 - 3.2e-19 68.8 41.7 3.2e-19 68.8 28.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 CEP18397.1 - 8.3e-37 126.7 29.3 3.6e-34 118.0 7.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP18397.1 - 1.1e-08 34.0 3.6 1.1e-08 34.0 2.5 3.0 1 1 2 4 4 4 1 Sugar (and other) transporter MFS_1_like PF12832.2 CEP18397.1 - 0.00068 19.3 0.7 0.17 11.6 0.0 3.3 2 1 1 3 3 3 1 MFS_1 like family BT1 PF03092.11 CEP18397.1 - 0.0013 17.5 0.2 0.0024 16.6 0.1 1.4 1 1 0 1 1 1 1 BT1 family MFS_2 PF13347.1 CEP18397.1 - 0.044 12.1 21.6 0.019 13.3 1.3 3.3 2 2 1 3 3 3 0 MFS/sugar transport protein NfeD PF01957.13 CEP18397.1 - 0.77 9.8 4.3 3.4 7.8 1.0 3.0 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding TPR_11 PF13414.1 CEP18398.1 - 4.6e-25 87.0 20.9 4.4e-06 26.2 0.1 6.0 5 1 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 CEP18398.1 - 1.1e-22 78.6 28.4 7.3e-05 22.2 0.1 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 CEP18398.1 - 1.6e-21 74.3 24.0 0.00033 20.3 0.0 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 CEP18398.1 - 7.1e-19 67.9 6.9 3.9e-07 30.5 0.6 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEP18398.1 - 1.3e-14 53.8 19.6 4.4e-06 26.5 0.1 6.5 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 CEP18398.1 - 6e-12 44.4 13.8 0.00053 19.5 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEP18398.1 - 7.3e-11 41.7 3.4 0.018 15.6 0.0 6.8 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP18398.1 - 9.1e-11 41.9 10.4 5.2e-05 23.5 0.4 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEP18398.1 - 4.9e-08 32.1 4.9 0.11 12.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP18398.1 - 1.1e-06 28.3 11.3 0.00078 19.4 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEP18398.1 - 2.4e-06 27.2 1.9 0.0038 17.0 0.1 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.3 CEP18398.1 - 2.8e-05 23.0 2.0 5.5e-05 22.1 1.4 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 CEP18398.1 - 5.9e-05 22.8 5.1 0.032 14.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 CEP18398.1 - 0.00018 20.7 2.7 5.5 5.9 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CEP18398.1 - 0.00052 20.0 2.3 0.27 11.3 0.2 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP18398.1 - 0.00066 19.9 8.7 8.7 7.0 0.0 6.7 6 1 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEP18398.1 - 0.8 9.6 0.0 0.8 9.6 0.0 4.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Carn_acyltransf PF00755.15 CEP18399.1 - 1.8e-183 610.8 0.1 2e-183 610.6 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-H2C2_2 PF13465.1 CEP18400.1 - 9.8e-09 35.0 12.2 2e-05 24.6 0.1 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEP18400.1 - 3.6e-08 33.2 7.8 9.7e-05 22.4 0.2 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP18400.1 - 0.00092 19.3 8.2 0.013 15.7 1.3 3.6 4 0 0 4 4 3 2 C2H2-type zinc finger zf-met PF12874.2 CEP18400.1 - 0.00097 19.2 0.4 0.00097 19.2 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP18400.1 - 0.014 15.5 0.7 0.014 15.5 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CEP18400.1 - 0.035 14.2 1.6 0.1 12.7 1.1 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 CEP18400.1 - 0.043 13.4 2.6 1.3 8.7 0.5 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 CEP18400.1 - 0.054 13.2 0.7 6.2 6.6 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger Trm112p PF03966.11 CEP18400.1 - 0.074 13.4 0.1 0.23 11.8 0.1 1.8 1 1 0 1 1 1 0 Trm112p-like protein CCDC84 PF14968.1 CEP18400.1 - 0.14 11.6 11.1 0.081 12.4 5.7 1.8 1 1 1 2 2 2 0 Coiled coil protein 84 zf-C2H2_6 PF13912.1 CEP18400.1 - 5.5 7.0 12.8 1.7 8.6 0.4 3.1 3 0 0 3 3 2 0 C2H2-type zinc finger zf-U1 PF06220.7 CEP18400.1 - 7.4 6.2 6.8 0.52 9.9 0.5 2.3 2 0 0 2 2 2 0 U1 zinc finger DUF3834 PF12916.2 CEP18401.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Peptidase_S10 PF00450.17 CEP18402.1 - 1.4e-112 376.9 0.1 1.7e-112 376.6 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CEP18402.1 - 0.00084 19.2 0.0 0.0029 17.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family RhoGEF PF00621.15 CEP18404.1 - 5.1e-33 114.4 0.7 8.5e-33 113.7 0.5 1.4 1 0 0 1 1 1 1 RhoGEF domain GrpE PF01025.14 CEP18405.1 - 4.5e-44 149.9 2.9 5.9e-44 149.5 2.0 1.2 1 0 0 1 1 1 1 GrpE B5 PF03484.10 CEP18405.1 - 0.018 14.8 0.1 0.093 12.5 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetase B5 domain GLE1 PF07817.8 CEP18405.1 - 0.63 8.9 5.4 0.23 10.3 1.7 1.6 2 0 0 2 2 2 0 GLE1-like protein Methyltransf_32 PF13679.1 CEP18406.1 - 8.6e-26 90.3 0.5 1.3e-25 89.6 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP18406.1 - 0.0027 18.2 0.0 0.0057 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CEP18406.1 - 0.0038 16.1 0.2 0.77 8.5 0.0 2.3 1 1 1 2 2 2 2 DREV methyltransferase MTS PF05175.9 CEP18406.1 - 0.01 15.2 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 CEP18406.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 CEP18406.1 - 0.033 14.1 0.1 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 CEP18406.1 - 0.065 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 CEP18406.1 - 0.1 12.0 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_23 PF13489.1 CEP18406.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_FMN PF00724.15 CEP18408.1 - 2.1e-100 336.0 0.0 2.4e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Isochorismatase PF00857.15 CEP18409.1 - 7.8e-35 120.3 0.0 8.6e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Silic_transp PF03842.8 CEP18409.1 - 0.029 12.4 0.0 0.037 12.0 0.0 1.1 1 0 0 1 1 1 0 Silicon transporter CIAPIN1 PF05093.8 CEP18410.1 - 1.6e-26 92.2 5.1 3.4e-26 91.2 3.6 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis RsgI_N PF12791.2 CEP18410.1 - 0.045 13.4 0.2 0.087 12.5 0.1 1.5 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Hydrolase_like2 PF13246.1 CEP18412.1 - 5.3e-15 55.1 0.0 5.1e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 CEP18412.1 - 7e-13 49.4 0.4 2.1e-11 44.6 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP18412.1 - 4.3e-12 46.6 0.4 1.7e-11 44.6 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEP18412.1 - 7.6e-12 44.7 3.6 1.2e-11 44.0 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.7 CEP18412.1 - 0.0012 18.5 0.3 0.0086 15.6 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase OmpH PF03938.9 CEP18412.1 - 0.012 15.5 2.1 0.41 10.5 0.7 3.2 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) UPF0449 PF15136.1 CEP18412.1 - 0.091 12.9 2.9 0.31 11.2 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 ECH PF00378.15 CEP18413.1 - 2.6e-23 82.4 0.0 5.6e-23 81.3 0.0 1.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CEP18413.1 - 6.1e-17 61.8 0.5 4.2e-10 39.8 0.0 3.4 3 1 1 4 4 4 2 2-enoyl-CoA Hydratase C-terminal region Glyco_hydro_42C PF08533.5 CEP18413.1 - 0.076 12.5 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain BRAP2 PF07576.7 CEP18415.1 - 3.4e-22 78.0 0.3 8.6e-22 76.7 0.2 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 CEP18415.1 - 1.1e-17 63.9 8.7 1.1e-17 63.9 6.1 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CEP18415.1 - 3.4e-09 36.3 10.7 3.4e-09 36.3 7.4 2.4 2 1 0 2 2 1 1 Ring finger domain zf-Apc11 PF12861.2 CEP18415.1 - 6.5e-07 29.1 1.7 6.5e-07 29.1 1.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CEP18415.1 - 2.5e-06 27.5 4.4 2.5e-06 27.5 3.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEP18415.1 - 0.00032 20.2 8.6 0.00032 20.2 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP18415.1 - 0.005 16.8 9.2 0.005 16.8 6.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP18415.1 - 0.0082 15.8 6.0 0.0082 15.8 4.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin_1 PF12718.2 CEP18415.1 - 0.012 15.4 14.8 0.026 14.3 10.3 1.6 1 0 0 1 1 1 0 Tropomyosin like zf-RING_UBOX PF13445.1 CEP18415.1 - 0.015 14.9 2.3 0.015 14.9 1.6 2.6 2 0 0 2 2 2 0 RING-type zinc-finger BSP PF04450.7 CEP18415.1 - 0.017 14.5 0.2 0.042 13.2 0.1 1.6 1 0 0 1 1 1 0 Peptidase of plants and bacteria TMF_TATA_bd PF12325.3 CEP18415.1 - 0.079 12.7 15.9 0.29 10.8 11.0 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 CEP18415.1 - 0.14 11.2 15.0 0.24 10.4 10.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 CEP18415.1 - 0.45 10.8 9.8 0.22 11.9 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HAUS6_N PF14661.1 CEP18415.1 - 0.58 9.4 6.9 0.95 8.7 4.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus zf-RING_4 PF14570.1 CEP18415.1 - 1.4 8.5 11.5 0.12 12.0 4.2 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain IncA PF04156.9 CEP18415.1 - 1.5 8.3 13.6 2.5 7.6 9.4 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CEP18415.1 - 3.5 5.3 7.0 5.4 4.7 4.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2046 PF09755.4 CEP18416.1 - 1.8e-26 92.7 18.5 5e-26 91.3 12.8 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) YbaB_DNA_bd PF02575.11 CEP18416.1 - 0.00031 20.5 0.7 0.00031 20.5 0.5 1.9 2 0 0 2 2 2 1 YbaB/EbfC DNA-binding family DUF2141 PF09912.4 CEP18416.1 - 0.033 13.8 0.0 0.085 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) LIM PF00412.17 CEP18417.1 - 3.7e-10 39.7 6.6 4.6e-10 39.4 4.6 1.1 1 0 0 1 1 1 1 LIM domain DUF4468 PF14730.1 CEP18417.1 - 0.091 12.4 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold DUF1265 PF06887.9 CEP18417.1 - 0.12 12.0 1.1 0.2 11.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) Auto_anti-p27 PF06677.7 CEP18417.1 - 0.89 9.3 5.0 5.4 6.8 1.8 2.7 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Nramp PF01566.13 CEP18418.1 - 4e-100 335.0 19.4 5e-100 334.7 13.5 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Ribosomal_L24e PF01246.15 CEP18420.1 - 1.7e-13 50.2 0.1 1.7e-13 50.2 0.1 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e adh_short PF00106.20 CEP18421.1 - 3.4e-26 92.1 0.9 7.1e-26 91.1 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP18421.1 - 9.6e-23 81.1 0.0 1.2e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP18421.1 - 1.4e-08 34.6 0.3 2.8e-08 33.6 0.2 1.5 1 1 0 1 1 1 1 KR domain bZIP_2 PF07716.10 CEP18422.1 - 2.7e-10 39.8 10.4 2.7e-10 39.8 7.2 1.8 2 0 0 2 2 2 1 Basic region leucine zipper XhlA PF10779.4 CEP18422.1 - 0.017 14.9 1.9 0.044 13.6 1.3 1.8 1 0 0 1 1 1 0 Haemolysin XhlA EMP24_GP25L PF01105.19 CEP18422.1 - 0.03 14.0 0.0 6.3 6.4 0.9 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD WD40_alt PF14077.1 CEP18422.1 - 0.044 13.4 1.7 0.077 12.6 1.2 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif bZIP_1 PF00170.16 CEP18422.1 - 0.47 10.4 19.6 0.045 13.6 9.0 2.4 2 1 0 2 2 2 0 bZIP transcription factor Herpes_UL25 PF01499.11 CEP18422.1 - 2.8 6.1 6.3 3.8 5.6 4.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Menin PF05053.8 CEP18423.1 - 3.7 5.6 6.9 3.9 5.5 4.8 1.0 1 0 0 1 1 1 0 Menin Methyltransf_16 PF10294.4 CEP18424.1 - 6.7e-30 103.8 1.2 1.5e-29 102.6 0.8 1.5 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CEP18424.1 - 8.4e-05 22.0 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CEP18424.1 - 0.00028 20.1 0.3 0.00051 19.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CEP18424.1 - 0.00085 19.8 0.1 0.0018 18.8 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP18424.1 - 0.0024 17.6 0.0 0.0045 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEP18424.1 - 0.027 14.0 0.1 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SeleniumBinding PF11524.3 CEP18424.1 - 0.14 12.3 0.5 0.36 10.9 0.1 1.8 2 0 0 2 2 2 0 Selenium binding protein Ded_cyto PF06920.8 CEP18425.1 - 2.8e-37 127.7 2.2 3.2e-37 127.5 0.6 1.9 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 CEP18425.1 - 1.5e-26 93.1 1.1 2e-18 66.6 0.0 4.8 3 1 0 3 3 3 2 C2 domain in Dock180 and Zizimin proteins HTH_23 PF13384.1 CEP18425.1 - 0.011 15.4 0.0 0.047 13.3 0.0 2.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.10 CEP18425.1 - 0.024 14.5 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase AIM24 PF01987.12 CEP18426.1 - 1.8e-05 24.3 0.0 3.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 GSIII_N PF12437.3 CEP18428.1 - 7.2e-65 217.3 0.0 1.4e-64 216.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 CEP18428.1 - 1.5e-37 129.1 0.0 2.2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Thi4 PF01946.12 CEP18429.1 - 1.9e-100 334.7 0.6 2.2e-100 334.4 0.4 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CEP18429.1 - 6.9e-12 44.9 1.0 5.6e-08 32.0 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEP18429.1 - 1.4e-07 30.7 1.1 0.00014 20.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CEP18429.1 - 3.1e-06 26.3 0.6 1.1e-05 24.5 0.4 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CEP18429.1 - 4.4e-06 26.6 0.3 1.3e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP18429.1 - 6.4e-06 26.1 0.2 2e-05 24.6 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP18429.1 - 5.9e-05 22.3 0.0 5.9e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CEP18429.1 - 7.9e-05 22.4 1.0 0.00068 19.4 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 CEP18429.1 - 0.00017 20.5 0.4 0.16 10.8 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 CEP18429.1 - 0.0053 15.2 0.1 0.0053 15.2 0.1 1.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.1 CEP18429.1 - 0.011 15.8 0.1 0.032 14.2 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 CEP18429.1 - 0.027 13.6 0.1 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Cauli_VI PF01693.11 CEP18429.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Caulimovirus viroplasmin Acetyltransf_1 PF00583.19 CEP18430.1 - 3.1e-11 43.1 0.1 5.6e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP18430.1 - 8.1e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP18430.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CEP18430.1 - 0.00054 20.0 0.1 0.00092 19.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 CEP18430.1 - 0.00091 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEP18430.1 - 0.0046 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 CEP18430.1 - 0.005 17.0 0.1 0.0093 16.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEP18430.1 - 0.0093 15.9 0.1 0.022 14.7 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP18430.1 - 0.025 14.4 0.0 0.039 13.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEP18430.1 - 0.031 14.1 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP18431.1 - 1.8e-09 37.4 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP18431.1 - 8.1e-09 35.5 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEP18431.1 - 0.00062 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 CEP18431.1 - 0.00099 19.2 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP18431.1 - 0.0017 18.0 0.0 0.0048 16.6 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CEP18431.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 CEP18431.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PFK PF00365.15 CEP18432.1 - 2.6e-173 574.5 5.7 9.6e-121 402.0 1.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase Mito_carr PF00153.22 CEP18432.1 - 3.8e-64 212.4 1.7 2.3e-22 78.4 0.0 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein E2F_TDP PF02319.15 CEP18433.1 - 1.1e-23 82.5 0.5 2.6e-23 81.3 0.3 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.5 CEP18433.1 - 2.3e-07 30.6 3.5 2.3e-07 30.6 2.4 2.2 2 0 0 2 2 2 1 Transcription factor DP YebO PF13974.1 CEP18433.1 - 0.014 15.1 3.2 0.014 15.1 2.2 2.5 1 1 1 2 2 2 0 YebO-like protein Activator_LAG-3 PF11498.3 CEP18433.1 - 0.12 11.0 30.2 0.19 10.4 21.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CBS PF00571.23 CEP18434.1 - 3.1e-40 135.6 7.4 8.9e-10 38.2 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 CEP18434.1 - 7e-09 35.2 3.0 1e-07 31.4 2.1 2.5 1 1 0 1 1 1 1 PB1 domain NYN PF01936.13 CEP18434.1 - 0.037 14.2 1.4 0.064 13.5 0.2 1.9 2 0 0 2 2 2 0 NYN domain KaiC PF06745.8 CEP18434.1 - 0.3 10.1 2.7 0.95 8.5 0.0 2.5 3 0 0 3 3 3 0 KaiC zf-RVT PF13966.1 CEP18436.1 - 0.018 15.3 0.5 0.018 15.3 0.3 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Polysacc_deac_3 PF15421.1 CEP18436.1 - 0.094 11.3 0.0 0.094 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase zf-ribbon_3 PF13248.1 CEP18438.1 - 0.36 10.0 2.6 0.72 9.1 1.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CEP18438.1 - 6.5 6.4 7.4 2.9 7.6 0.2 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Kelch_1 PF01344.20 CEP18439.1 - 8.4e-15 54.0 6.9 0.0074 15.8 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 CEP18439.1 - 4.4e-12 45.5 7.3 0.0026 17.4 0.1 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP18439.1 - 5.4e-12 45.3 7.9 0.027 14.6 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 CEP18439.1 - 1.1e-11 44.4 5.0 0.0035 17.2 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 CEP18439.1 - 9.8e-10 38.3 5.8 0.018 15.1 0.0 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CEP18439.1 - 8.2e-07 28.5 0.6 1.5 8.6 0.0 5.4 5 0 0 5 5 5 2 Kelch motif DUF3290 PF11694.3 CEP18439.1 - 0.068 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Gly-zipper_YMGG PF13441.1 CEP18440.1 - 0.16 11.5 10.7 0.25 10.8 0.6 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 CEP18440.1 - 1.7 8.8 8.2 5.7 7.1 1.3 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 CEP18440.1 - 3.5 7.3 10.2 7.4 6.2 1.0 3.3 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain RVT_1 PF00078.22 CEP18441.1 - 4.3e-20 71.9 0.0 3.1e-10 39.7 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP18441.1 - 7.6e-05 22.7 0.7 0.00014 21.8 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Arginase PF00491.16 CEP18441.1 - 0.092 12.0 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Arginase family Amidase02_C PF12123.3 CEP18441.1 - 0.13 11.9 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase zf-CCHC_4 PF14392.1 CEP18442.1 - 0.005 16.4 2.9 0.7 9.6 0.0 2.7 2 0 0 2 2 2 2 Zinc knuckle DEAD_assoc PF08494.6 CEP18442.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/H associated YL1 PF05764.8 CEP18442.1 - 0.1 12.1 13.1 0.014 15.0 3.8 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Mucin PF01456.12 CEP18442.1 - 0.6 9.8 6.9 1.4 8.6 4.8 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein HNH PF01844.18 CEP18443.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 0 HNH endonuclease RRM_1 PF00076.17 CEP18443.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 CEP18444.1 - 8.1e-34 116.3 0.0 8.6e-34 116.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP18444.1 - 2.8e-10 40.7 0.0 3.4e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP18444.1 - 2.4e-07 30.1 0.0 2.6e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP18444.1 - 0.0072 15.4 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEP18444.1 - 0.0088 15.2 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CEP18444.1 - 0.042 13.3 0.2 0.12 11.8 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CEP18444.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CEP18444.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase F-box-like PF12937.2 CEP18445.1 - 4.9e-08 32.5 0.7 1.1e-07 31.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like Fungal_trans PF04082.13 CEP18447.1 - 2.5e-21 75.7 0.5 2.5e-21 75.7 0.4 3.1 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP18447.1 - 7e-11 41.8 12.2 1.4e-10 40.9 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med15 PF09606.5 CEP18447.1 - 1.1e-06 27.1 66.9 1.7e-06 26.6 19.4 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4011 PF13195.1 CEP18447.1 - 0.87 9.5 12.9 1.1 9.2 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DUF4557 PF15101.1 CEP18447.1 - 1.1 9.0 37.6 2.7 7.7 6.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF1360 PF07098.6 CEP18447.1 - 9.1 6.0 6.0 5.6 6.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Ribosomal_L3 PF00297.17 CEP18448.1 - 3.7e-40 137.9 1.6 1.5e-38 132.7 1.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 PDZ_assoc PF10600.4 CEP18449.1 - 0.02 15.1 0.2 0.044 14.0 0.1 1.7 1 1 1 2 2 2 0 PDZ-associated domain of NMDA receptors Pkinase PF00069.20 CEP18452.1 - 1.5e-36 125.8 0.1 2.1e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18452.1 - 8.8e-17 61.0 0.1 9.2e-14 51.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CEP18452.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 CEP18453.1 - 1.6e-54 184.7 0.0 1.9e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_trans_1_4 PF13692.1 CEP18453.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF2422 PF10337.4 CEP18454.1 - 1e-18 67.4 12.5 3.6e-17 62.3 7.5 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CEP18454.1 - 2e-12 47.2 0.1 4.3e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 CEP18454.1 - 1.5e-07 31.3 14.9 1.5e-07 31.3 10.3 3.3 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 CEP18454.1 - 4.7e-06 25.5 0.1 4.7e-06 25.5 0.1 2.6 3 1 0 3 3 3 1 Aluminium activated malate transporter FUSC PF04632.7 CEP18454.1 - 3 6.1 19.9 0.5 8.7 2.8 3.3 2 2 1 3 3 3 0 Fusaric acid resistance protein family Pkinase PF00069.20 CEP18455.1 - 1.4e-51 175.1 0.0 2.4e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18455.1 - 5.4e-23 81.3 0.0 8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP18455.1 - 9.2e-06 24.8 0.1 0.0002 20.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CEP18455.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family N-Term_TEN PF11474.3 CEP18456.1 - 0.0043 16.4 0.4 0.0057 16.0 0.3 1.1 1 0 0 1 1 1 1 Telomerase reverse transcriptase TEN domain UQ_con PF00179.21 CEP18457.1 - 2.8e-16 59.2 1.1 3.1e-16 59.0 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme CLASP_N PF12348.3 CEP18458.1 - 5.4e-38 130.6 2.1 5.4e-38 130.6 1.5 1.6 2 0 0 2 2 2 1 CLASP N terminal DUF1546 PF07571.8 CEP18458.1 - 0.0083 16.2 0.1 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) HEAT PF02985.17 CEP18458.1 - 0.01 15.8 0.0 7.6 6.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat BC10 PF06726.7 CEP18458.1 - 0.052 13.5 0.7 0.18 11.8 0.2 2.2 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Cohesin_HEAT PF12765.2 CEP18458.1 - 0.053 13.5 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion RVT_1 PF00078.22 CEP18460.1 - 1.3e-19 70.4 0.0 2.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CEP18460.1 - 2.3e-05 24.1 0.0 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CEP18460.1 - 8.1e-05 23.0 0.0 0.00021 21.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 CEP18461.1 - 1.5e-08 34.5 4.5 2e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 Retrotransposon gag protein zf-CCHC PF00098.18 CEP18461.1 - 7.4e-08 31.9 2.1 1.2e-07 31.3 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF1473 PF07341.6 CEP18461.1 - 0.0073 15.8 1.4 0.41 10.1 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1473) zf-CCHC_4 PF14392.1 CEP18461.1 - 0.023 14.3 0.5 0.058 13.0 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Coagulin PF02035.10 CEP18461.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Coagulin zf-CCHC_6 PF15288.1 CEP18461.1 - 0.082 12.5 0.6 0.19 11.3 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_5 PF13873.1 CEP18463.1 - 0.015 15.2 0.3 0.83 9.5 0.1 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain COX6A PF02046.10 CEP18464.1 - 1.2e-27 96.0 0.9 1.3e-27 95.9 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.27 CEP18466.1 - 5.8e-69 225.7 12.9 1.6e-10 40.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CEP18466.1 - 1.1e-24 86.3 7.5 2e-24 85.5 5.2 1.4 1 0 0 1 1 1 1 Tup N-terminal eIF2A PF08662.6 CEP18466.1 - 0.00011 21.9 0.0 0.14 11.8 0.0 3.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CEP18466.1 - 0.00014 20.3 0.1 0.0012 17.1 0.0 2.3 1 1 2 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 CEP18466.1 - 0.00029 20.0 0.1 1.9 7.5 0.0 3.3 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 CEP18466.1 - 0.003 17.1 0.5 19 5.0 0.0 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Spc7 PF08317.6 CEP18466.1 - 0.0078 14.9 0.8 0.012 14.2 0.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 CEP18466.1 - 0.0097 15.6 4.5 0.02 14.6 3.1 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 CEP18466.1 - 0.017 14.3 6.8 0.038 13.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Nup160 PF11715.3 CEP18466.1 - 0.036 12.2 0.2 3.5 5.6 0.0 3.1 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Tektin PF03148.9 CEP18466.1 - 0.048 12.1 2.4 0.073 11.5 1.7 1.1 1 0 0 1 1 1 0 Tektin family Proteasome_A_N PF10584.4 CEP18466.1 - 0.11 11.8 2.1 7.2 6.0 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature APG6 PF04111.7 CEP18466.1 - 0.34 9.9 4.4 0.5 9.3 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CP2 PF04516.10 CEP18467.1 - 1.6e-59 200.8 0.1 2.3e-59 200.3 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor ATP-synt_ab PF00006.20 CEP18468.1 - 9.2e-64 214.8 0.0 1.9e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEP18468.1 - 1.8e-24 86.3 1.0 3e-24 85.6 0.7 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEP18468.1 - 4e-24 84.6 2.4 8.3e-24 83.5 1.2 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain MobB PF03205.9 CEP18468.1 - 0.0024 17.5 0.1 0.92 9.2 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CEP18468.1 - 0.0034 17.1 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CEP18468.1 - 0.0056 16.3 0.1 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CEP18468.1 - 0.011 15.7 0.3 0.033 14.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 CEP18468.1 - 0.018 14.1 0.1 0.034 13.2 0.1 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 CEP18468.1 - 0.018 13.8 0.9 0.034 13.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 CEP18468.1 - 0.037 13.4 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CEP18468.1 - 0.038 14.2 0.1 0.46 10.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP18468.1 - 0.042 13.9 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CEP18468.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CEP18468.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP-synt_DE_N PF02823.11 CEP18469.1 - 2.3e-20 72.1 0.2 3.3e-20 71.6 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF1542 PF07564.6 CEP18469.1 - 0.18 11.8 3.0 4.7 7.2 0.7 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DHFR_1 PF00186.14 CEP18470.1 - 1.4e-19 70.2 0.0 9.4e-10 38.2 0.0 2.3 2 1 0 2 2 2 2 Dihydrofolate reductase Adaptin_N PF01602.15 CEP18471.1 - 6.7e-107 357.9 10.0 9.7e-107 357.4 6.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CEP18471.1 - 7.6e-68 226.2 0.4 2.1e-67 224.7 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CEP18471.1 - 1.4e-60 203.0 0.9 1.4e-60 203.0 0.6 2.3 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CEP18471.1 - 1.4e-15 57.3 6.4 5.3e-07 29.8 0.0 4.9 1 1 2 4 4 4 2 HEAT repeats HEAT PF02985.17 CEP18471.1 - 1.6e-06 27.7 0.0 0.0045 16.9 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 CEP18471.1 - 1.1e-05 25.7 1.4 0.045 14.2 0.0 4.4 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 CEP18471.1 - 0.00057 19.7 5.4 0.18 11.6 0.0 4.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 BDV_G PF06208.6 CEP18471.1 - 0.0015 17.5 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Borna disease virus G protein Arm PF00514.18 CEP18471.1 - 0.72 9.7 3.3 19 5.2 0.1 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FAD-oxidase_C PF02913.14 CEP18472.1 - 2.2e-62 210.5 0.0 3e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CEP18472.1 - 1.1e-36 125.3 0.0 2.3e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain CAP_GLY PF01302.20 CEP18473.1 - 2e-19 69.0 0.0 3.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.26 CEP18473.1 - 4.3e-16 58.8 0.9 3.7e-12 46.2 0.2 2.7 2 0 0 2 2 2 2 BTB/POZ domain COG4 PF08318.7 CEP18474.1 - 4e-71 239.4 3.3 4e-71 239.4 2.3 2.0 2 0 0 2 2 2 1 COG4 transport protein WD40 PF00400.27 CEP18475.1 - 6.5e-24 82.8 11.9 0.00013 21.6 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CEP18475.1 - 0.00021 19.5 0.0 0.48 8.4 0.0 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF3659 PF12396.3 CEP18475.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) BTV_NS2 PF04514.7 CEP18475.1 - 2.5 6.9 10.4 4 6.2 7.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 CEP18475.1 - 4.7 5.1 12.7 7.4 4.4 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 CEP18475.1 - 6.7 6.3 6.5 15 5.2 4.5 1.6 1 0 0 1 1 1 0 FAM176 family RVT_1 PF00078.22 CEP18476.1 - 7.6e-05 22.1 0.0 8.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PPR_2 PF13041.1 CEP18479.1 - 3.1e-28 97.4 4.2 3.5e-08 33.2 0.0 7.0 5 2 2 7 7 7 6 PPR repeat family PPR_1 PF12854.2 CEP18479.1 - 1.1e-11 43.9 5.8 0.02 14.3 0.0 6.6 7 0 0 7 7 7 4 PPR repeat PPR_3 PF13812.1 CEP18479.1 - 6.5e-10 38.4 0.1 0.0038 17.3 0.0 6.8 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR PF01535.15 CEP18479.1 - 3.8e-07 29.6 6.8 0.0059 16.5 0.0 7.1 7 1 0 7 7 7 1 PPR repeat TPR_19 PF14559.1 CEP18479.1 - 0.00045 20.5 1.4 0.77 10.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat RST PF12174.3 CEP18479.1 - 0.006 16.3 0.2 0.043 13.6 0.0 2.7 3 0 0 3 3 3 1 RCD1-SRO-TAF4 (RST) plant domain Apc3 PF12895.2 CEP18479.1 - 0.0088 16.1 0.2 0.084 13.0 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CEP18479.1 - 0.028 14.8 4.6 0.31 11.5 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEP18479.1 - 0.049 13.5 1.1 0.21 11.4 0.3 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 CEP18479.1 - 0.13 12.1 0.5 0.56 10.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_25 PF13481.1 CEP18480.1 - 2.2e-17 63.1 0.0 4.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP18480.1 - 9.9e-09 35.4 0.0 3.6e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Toprim_4 PF13662.1 CEP18480.1 - 3.2e-06 27.0 0.0 3.2e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Toprim domain DnaB_C PF03796.10 CEP18480.1 - 5.6e-05 22.1 0.0 0.00012 21.0 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain KaiC PF06745.8 CEP18480.1 - 7.1e-05 22.0 0.0 0.00018 20.6 0.0 1.7 1 1 0 1 1 1 1 KaiC ABC_tran PF00005.22 CEP18480.1 - 0.0004 20.6 0.0 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Toprim_2 PF13155.1 CEP18480.1 - 0.00082 19.6 0.0 0.0033 17.7 0.0 2.0 2 0 0 2 2 2 1 Toprim-like AAA_29 PF13555.1 CEP18480.1 - 0.0015 18.0 0.2 0.0043 16.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP18480.1 - 0.0016 18.4 0.0 0.0044 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CEP18480.1 - 0.0021 17.2 0.1 0.071 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CEP18480.1 - 0.0025 18.1 0.2 0.0025 18.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CEP18480.1 - 0.0027 17.1 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Toprim_3 PF13362.1 CEP18480.1 - 0.0065 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Toprim domain AAA_17 PF13207.1 CEP18480.1 - 0.0079 17.0 0.7 0.031 15.1 0.1 2.5 3 1 0 3 3 1 1 AAA domain AAA_14 PF13173.1 CEP18480.1 - 0.01 15.7 0.2 0.057 13.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CEP18480.1 - 0.015 15.2 0.0 0.048 13.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 CEP18480.1 - 0.037 13.7 0.6 6.1 6.5 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MutS_V PF00488.16 CEP18480.1 - 0.039 13.3 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 MutS domain V AAA_19 PF13245.1 CEP18480.1 - 0.058 13.1 0.4 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 CEP18480.1 - 0.064 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CEP18480.1 - 0.069 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CEP18480.1 - 0.15 11.7 1.7 0.25 11.0 0.2 2.1 2 0 0 2 2 2 0 NTPase Zn_Tnp_IS1595 PF12760.2 CEP18480.1 - 0.18 11.6 1.0 0.43 10.4 0.7 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RNA_pol_Rpc82 PF05645.8 CEP18481.1 - 9.8e-10 38.3 1.9 3.6e-08 33.2 1.3 2.4 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 CEP18481.1 - 2.3e-05 24.1 0.2 0.0021 17.8 0.1 2.9 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain Transcrip_reg PF01709.15 CEP18481.1 - 0.058 12.5 3.2 0.87 8.6 0.0 2.6 3 0 0 3 3 3 0 Transcriptional regulator HTH_9 PF08221.6 CEP18482.1 - 3.5e-20 71.6 0.0 2.2e-15 56.2 0.1 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 CEP18482.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 TFIIE alpha subunit RVT_1 PF00078.22 CEP18483.1 - 4.2e-19 68.7 0.0 1.1e-18 67.3 0.0 1.6 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gal4_dimer PF03902.8 CEP18483.1 - 0.067 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF4355 PF14265.1 CEP18485.1 - 0.068 13.1 0.4 0.08 12.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1635 PF07795.6 CEP18485.1 - 0.09 12.1 3.0 0.11 11.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MAP7 PF05672.6 CEP18486.1 - 0.0015 17.9 13.4 0.0015 17.9 9.3 1.9 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family MIP-T3 PF10243.4 CEP18486.1 - 3.6 5.9 35.7 4.9 5.4 24.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NOA36 PF06524.7 CEP18487.1 - 3.8 6.6 7.4 5.3 6.1 5.1 1.1 1 0 0 1 1 1 0 NOA36 protein JmjC PF02373.17 CEP18488.1 - 9.9e-18 64.4 0.0 2.8e-17 62.9 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ZZ PF00569.12 CEP18488.1 - 0.0034 16.8 12.9 0.0034 16.8 9.0 3.3 3 0 0 3 3 3 1 Zinc finger, ZZ type DUF787 PF05619.6 CEP18488.1 - 0.019 13.6 0.1 0.034 12.8 0.1 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Cupin_2 PF07883.6 CEP18488.1 - 0.036 13.5 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Desulfoferrod_N PF06397.7 CEP18488.1 - 5.5 6.4 8.3 1.5 8.2 0.0 3.3 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain RabGAP-TBC PF00566.13 CEP18489.1 - 1.8e-49 168.1 1.1 1.8e-49 168.1 0.8 2.4 2 1 1 3 3 3 1 Rab-GTPase-TBC domain SPAM PF02090.10 CEP18489.1 - 0.005 16.8 6.2 0.005 16.8 4.3 2.6 2 1 1 3 3 3 1 Salmonella surface presentation of antigen gene type M protein DUF4201 PF13870.1 CEP18489.1 - 0.019 14.4 20.2 0.048 13.1 7.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 CEP18489.1 - 0.02 14.7 22.1 0.21 11.4 13.9 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CEP18489.1 - 0.19 11.2 25.9 0.11 12.1 6.4 3.0 2 1 1 3 3 3 0 IncA protein Phage_GPO PF05929.6 CEP18489.1 - 0.23 10.6 9.0 0.72 9.0 6.2 1.8 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIVA PF05103.8 CEP18489.1 - 0.46 10.5 20.5 0.9 9.5 2.5 4.0 1 1 0 2 2 2 0 DivIVA protein Cep57_CLD_2 PF14197.1 CEP18489.1 - 0.63 10.0 20.0 0.39 10.6 8.9 4.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 TMF_TATA_bd PF12325.3 CEP18489.1 - 0.65 9.7 19.9 1.1 9.0 6.3 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 CEP18489.1 - 1.9 8.2 10.0 0.15 11.8 2.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 CEP18489.1 - 3.8 7.1 21.0 0.75 9.4 6.3 2.9 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 FUSC PF04632.7 CEP18489.1 - 7.3 4.8 4.5 11 4.2 3.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 CEP18489.1 - 9.5 5.1 22.9 1.1 8.2 8.0 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 MYEOV2 PF15004.1 CEP18490.1 - 0.0031 18.0 1.0 0.0031 18.0 0.7 2.0 2 0 0 2 2 2 1 Myeloma-overexpressed-like DUF2890 PF11081.3 CEP18490.1 - 0.15 12.1 2.1 0.17 11.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) tRNA-synt_2b PF00587.20 CEP18491.1 - 1.5e-45 154.8 0.0 2.7e-45 154.0 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEP18491.1 - 4.6e-22 77.7 0.0 8.6e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain DUF2146 PF10220.4 CEP18493.1 - 2.5e-69 234.2 7.0 8.2e-31 106.8 3.1 5.0 5 0 0 5 5 5 5 Uncharacterized conserved protein (DUF2146) PQ-loop PF04193.9 CEP18494.1 - 2.6e-21 74.9 14.6 6.7e-13 47.9 1.5 3.2 4 0 0 4 4 4 2 PQ loop repeat MtN3_slv PF03083.11 CEP18494.1 - 8.7 6.2 13.7 16 5.4 2.3 3.0 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange WCOR413 PF05562.6 CEP18494.1 - 9.7 5.6 11.6 0.67 9.4 2.5 2.8 2 2 1 3 3 3 0 Cold acclimation protein WCOR413 E1-E2_ATPase PF00122.15 CEP18495.1 - 7.3e-29 100.4 0.4 7.3e-29 100.4 0.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEP18495.1 - 1.9e-17 64.4 0.0 6.4e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP18495.1 - 1.2e-14 54.9 0.0 2.7e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP18495.1 - 0.00013 21.3 0.5 0.00035 19.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CEP18495.1 - 0.028 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEP18495.1 - 0.065 12.8 3.2 0.23 11.0 0.0 3.0 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase Mannosyl_trans2 PF04188.8 CEP18496.1 - 3.3e-62 210.8 24.8 4.2e-62 210.5 17.2 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Type_III_YscX PF09474.5 CEP18497.1 - 0.42 10.6 2.7 0.52 10.3 0.6 2.1 1 1 1 2 2 2 0 Type III secretion system YscX (type_III_YscX) Ank PF00023.25 CEP18498.1 - 1e-30 103.9 0.9 5.8e-07 29.0 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 CEP18498.1 - 2e-30 104.5 1.5 1e-10 41.8 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEP18498.1 - 4.3e-29 100.6 1.9 4e-15 55.9 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP18498.1 - 4.4e-25 87.1 1.8 1.3e-10 41.1 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP18498.1 - 7.7e-23 78.2 3.3 5.2e-06 26.1 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.16 CEP18498.1 - 6.8e-18 64.3 6.4 1.2e-17 63.4 4.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 CEP18498.1 - 0.00019 21.3 7.3 0.00059 19.7 5.0 1.9 1 1 0 1 1 1 1 FYVE-type zinc finger Pex24p PF06398.6 CEP18498.1 - 0.0016 17.3 6.5 0.0026 16.6 4.5 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin AAA_12 PF13087.1 CEP18498.1 - 0.022 14.1 2.2 0.038 13.3 1.5 1.3 1 0 0 1 1 1 0 AAA domain MscS_TM PF12794.2 CEP18498.1 - 0.18 10.4 1.5 0.27 9.7 1.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Sel1 PF08238.7 CEP18499.1 - 2.1e-18 66.3 24.2 1.1e-06 29.0 0.3 8.3 8 0 0 8 8 8 5 Sel1 repeat TPR_7 PF13176.1 CEP18499.1 - 0.00018 21.0 0.3 0.0012 18.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP18499.1 - 0.00021 20.9 3.0 0.0023 17.7 0.4 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEP18499.1 - 0.0017 17.8 0.3 0.0017 17.8 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP18499.1 - 0.013 16.0 1.5 0.063 13.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEP18499.1 - 0.019 14.7 3.3 0.32 10.8 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEP18499.1 - 0.021 14.4 1.7 0.092 12.4 0.3 2.7 2 0 0 2 2 2 0 TPR repeat RPN7 PF10602.4 CEP18499.1 - 0.19 11.0 3.1 0.51 9.7 0.1 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 CEP18499.1 - 0.55 10.8 6.7 3.7 8.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP18499.1 - 1.9 8.4 6.7 1 9.3 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DIL PF01843.14 CEP18500.1 - 8e-24 83.5 2.1 2.2e-23 82.1 1.5 1.8 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 CEP18500.1 - 4.3e-16 59.0 0.1 9.2e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEP18500.1 - 8.4e-14 50.5 0.3 6e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CEP18500.1 - 2.7e-11 43.3 0.3 1e-06 28.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP18500.1 - 9.6e-10 38.7 0.3 0.0012 19.3 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP18500.1 - 1.4e-09 37.2 0.3 0.00051 20.0 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Orbi_VP5 PF00901.12 CEP18500.1 - 0.47 8.5 5.4 0.14 10.3 1.5 1.7 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 CENP-B_dimeris PF09026.5 CEP18500.1 - 4.8 7.4 18.9 9.5 6.5 4.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1168 PF06658.7 CEP18501.1 - 1e-36 125.5 16.8 1e-36 125.5 11.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Pecanex_C PF05041.10 CEP18501.1 - 0.0063 15.5 0.6 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Pecanex protein (C-terminus) BSMAP PF12280.3 CEP18501.1 - 0.24 11.2 5.0 0.35 10.7 3.4 1.5 1 1 0 1 1 1 0 Brain specific membrane anchored protein DHDPS PF00701.17 CEP18504.1 - 2.5e-50 170.7 0.0 2.8e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Inp1 PF12634.2 CEP18504.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 Ribosomal_L22 PF00237.14 CEP18505.1 - 2.5e-22 78.8 0.4 4.3e-22 78.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Rep_4 PF05797.6 CEP18505.1 - 0.043 12.5 0.1 0.06 12.0 0.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Opi1 PF08618.5 CEP18506.1 - 2.7e-47 161.6 13.5 1.3e-39 136.4 5.7 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 Transposase_23 PF03017.9 CEP18506.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 TNP1/EN/SPM transposase IPK PF03770.11 CEP18507.1 - 6.2e-46 156.5 0.1 6.2e-46 156.5 0.0 2.5 2 0 0 2 2 2 1 Inositol polyphosphate kinase PAT1 PF09770.4 CEP18507.1 - 0.0016 16.7 16.4 0.0019 16.5 11.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CEP18507.1 - 0.013 15.5 7.2 0.025 14.6 5.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ycf1 PF05758.7 CEP18507.1 - 0.11 10.2 6.1 0.12 10.0 4.2 1.1 1 0 0 1 1 1 0 Ycf1 CMS1 PF14617.1 CEP18507.1 - 0.29 10.1 5.4 0.56 9.2 3.7 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Neur_chan_memb PF02932.11 CEP18507.1 - 0.41 10.4 3.0 0.56 10.0 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.1 CEP18507.1 - 0.72 9.5 6.4 1.5 8.4 4.5 1.5 1 0 0 1 1 1 0 FAM176 family Ndc1_Nup PF09531.5 CEP18507.1 - 0.83 7.9 5.1 1.2 7.5 3.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PBP1_TM PF14812.1 CEP18507.1 - 1.1 9.6 7.0 2.3 8.5 4.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4338 PF14236.1 CEP18507.1 - 1.2 7.7 7.2 12 4.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4338) RED_N PF07808.8 CEP18507.1 - 1.3 8.1 15.4 2.3 7.3 10.7 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region CRF1 PF10380.4 CEP18507.1 - 2 8.8 7.4 0.72 10.2 3.4 1.5 2 0 0 2 2 1 0 Transcription factor CRF1 Glyco_transf_15 PF01793.11 CEP18507.1 - 2.4 6.9 9.6 3.8 6.3 6.7 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Ctr PF04145.10 CEP18507.1 - 3.8 7.5 5.2 7.6 6.5 2.8 1.9 2 1 0 2 2 2 0 Ctr copper transporter family Hid1 PF12722.2 CEP18507.1 - 6.8 4.2 11.3 9.5 3.7 7.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHHW PF14286.1 CEP18507.1 - 7.4 5.7 11.7 70 2.5 0.0 2.1 2 0 0 2 2 2 0 DHHW protein EIIBC-GUT_N PF03612.9 CEP18507.1 - 7.7 6.0 9.0 17 4.9 6.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SET PF00856.23 CEP18508.1 - 1.1e-11 45.2 1.5 9.2e-10 39.0 1.0 2.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 CEP18508.1 - 0.00056 19.7 13.3 0.00056 19.7 9.2 2.0 2 0 0 2 2 2 1 MYND finger DUF960 PF06124.6 CEP18508.1 - 0.016 15.4 0.2 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) HTH_21 PF13276.1 CEP18508.1 - 0.026 14.5 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain Myb_DNA-bind_6 PF13921.1 CEP18509.1 - 1.6e-34 117.8 1.5 2.5e-16 59.5 0.0 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP18509.1 - 7.4e-33 112.3 10.4 4.5e-14 52.2 0.2 3.7 3 1 0 3 3 3 3 Myb-like DNA-binding domain SR-25 PF10500.4 CEP18509.1 - 0.00039 19.9 10.3 0.00065 19.2 7.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-DHHC PF01529.15 CEP18509.1 - 0.09 12.1 0.6 0.12 11.7 0.4 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase CDC45 PF02724.9 CEP18509.1 - 0.18 9.7 18.6 0.33 8.9 12.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CEP18509.1 - 0.65 9.7 10.5 1.2 8.9 7.3 1.5 1 0 0 1 1 1 0 DDHD domain AUX_IAA PF02309.11 CEP18509.1 - 0.67 9.6 12.2 1.1 8.9 8.5 1.3 1 0 0 1 1 1 0 AUX/IAA family Rap1_C PF11626.3 CEP18509.1 - 0.85 9.5 13.4 52 3.8 0.0 4.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Suf PF05843.9 CEP18509.1 - 1.8 8.2 22.3 3.1 7.4 15.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF913 PF06025.7 CEP18509.1 - 2.3 6.8 11.8 3.3 6.3 8.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_23 PF13476.1 CEP18509.1 - 2.4 8.4 16.9 3.5 7.8 11.7 1.2 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 CEP18509.1 - 2.6 5.6 14.6 3.2 5.3 10.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BTV_NS2 PF04514.7 CEP18509.1 - 2.9 6.6 16.6 4.4 6.0 11.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 CEP18509.1 - 3.7 7.2 13.0 7.6 6.2 9.0 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DUF106 PF01956.11 CEP18509.1 - 6.1 6.3 8.2 9.9 5.6 5.7 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF4557 PF15101.1 CEP18509.1 - 7.4 6.3 24.5 3.5 7.4 15.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) GUB_WAK_bind PF13947.1 CEP18510.1 - 0.14 12.7 0.5 0.43 11.1 0.1 2.0 2 0 0 2 2 2 0 Wall-associated receptor kinase galacturonan-binding eIF_4EBP PF05456.6 CEP18511.1 - 2e-07 30.6 0.1 2.4e-07 30.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Abhydrolase_3 PF07859.8 CEP18512.1 - 3.2e-58 196.7 0.0 4.1e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CEP18512.1 - 5.2e-08 32.0 0.4 6e-07 28.5 0.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 CEP18512.1 - 8e-08 31.3 0.0 9.7e-08 31.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CEP18512.1 - 0.0018 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CEP18512.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 CEP18512.1 - 0.033 13.4 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.6 CEP18512.1 - 0.048 13.3 0.3 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.2 CEP18512.1 - 0.075 11.9 0.1 0.13 11.0 0.1 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme PA28_alpha PF02251.13 CEP18512.1 - 0.084 13.0 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Esterase PF00756.15 CEP18512.1 - 0.17 11.2 0.0 18 4.6 0.0 2.4 2 0 0 2 2 2 0 Putative esterase MFS_1 PF07690.11 CEP18513.1 - 2.1e-13 49.7 60.1 5.2e-13 48.4 40.6 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CEP18513.1 - 0.0017 16.6 32.5 0.0025 16.0 22.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease_2 PF13520.1 CEP18516.1 - 4.4e-53 180.3 43.0 5.4e-53 180.0 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEP18516.1 - 1.1e-20 73.5 34.1 1.5e-20 73.0 23.6 1.2 1 0 0 1 1 1 1 Amino acid permease SecE PF00584.15 CEP18517.1 - 3e-12 45.9 0.0 3.6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF383 PF04063.9 CEP18518.1 - 1.6e-57 194.2 0.3 4.6e-57 192.6 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CEP18518.1 - 1.2e-16 60.0 0.4 3.1e-16 58.6 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Dna2 PF08696.6 CEP18521.1 - 3.3e-54 183.3 1.1 5.9e-54 182.5 0.8 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 CEP18521.1 - 7.7e-53 178.8 0.4 7.2e-52 175.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CEP18521.1 - 1.6e-38 132.6 0.1 5.2e-21 75.3 0.0 2.8 1 1 1 2 2 2 2 AAA domain NTF2 PF02136.15 CEP18521.1 - 3.1e-22 79.1 0.2 1.4e-21 77.0 0.1 2.3 2 0 0 2 2 1 1 Nuclear transport factor 2 (NTF2) domain AAA_30 PF13604.1 CEP18521.1 - 4.1e-12 46.0 0.0 1.2e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP18521.1 - 1.2e-08 34.5 0.1 3.1e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Mtr2 PF10429.4 CEP18521.1 - 1.4e-07 31.3 0.0 3.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Cas_Cas4 PF01930.12 CEP18521.1 - 2e-07 31.0 0.1 2.9e-06 27.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 CEP18521.1 - 4e-07 29.6 0.0 8.6e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Helicase_RecD PF05127.9 CEP18521.1 - 1.2e-05 25.0 0.0 0.0001 21.9 0.0 2.4 2 0 0 2 2 2 1 Helicase SRP54 PF00448.17 CEP18521.1 - 0.00036 20.0 0.0 0.0008 18.8 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 CEP18521.1 - 0.0014 18.0 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 CEP18521.1 - 0.0017 17.7 0.3 0.043 13.1 0.0 2.6 2 1 1 3 3 2 1 AAA domain T2SE PF00437.15 CEP18521.1 - 0.0025 16.7 0.0 0.0054 15.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PIF1 PF05970.9 CEP18521.1 - 0.0034 16.3 0.0 0.078 11.9 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.16 CEP18521.1 - 0.0036 16.6 1.1 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CEP18521.1 - 0.0046 17.0 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.10 CEP18521.1 - 0.014 15.1 0.2 0.014 15.1 0.1 2.7 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CEP18521.1 - 0.015 15.3 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 CEP18521.1 - 0.018 14.7 0.0 0.071 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CEP18521.1 - 0.022 14.6 1.4 0.11 12.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 CEP18521.1 - 0.024 14.3 0.2 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 CEP18521.1 - 0.027 13.6 0.0 0.087 11.9 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA PF00004.24 CEP18521.1 - 0.046 13.9 0.1 0.24 11.5 0.0 2.3 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEP18521.1 - 0.11 12.6 0.4 0.81 9.8 0.1 2.7 2 1 1 3 3 3 0 AAA domain Rap_GAP PF02145.10 CEP18522.1 - 3.3e-33 114.6 0.0 3.8e-25 88.3 0.0 2.7 1 1 1 2 2 2 2 Rap/ran-GAP Mucin PF01456.12 CEP18522.1 - 9.5 5.9 19.9 10 5.9 6.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein G-alpha PF00503.15 CEP18523.1 - 3.8e-127 424.2 4.8 4.6e-127 423.9 3.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP18523.1 - 4.4e-16 58.6 0.3 4e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP18523.1 - 0.00024 20.3 2.8 0.017 14.2 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP18523.1 - 0.00027 21.3 0.2 1.3 9.4 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein zf-CHC2 PF01807.15 CEP18523.1 - 0.015 14.8 0.1 0.15 11.6 0.0 2.4 2 0 0 2 2 2 0 CHC2 zinc finger AAA_29 PF13555.1 CEP18523.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.18 CEP18523.1 - 0.038 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 CEP18523.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 CEP18523.1 - 0.075 12.4 0.1 6.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP18523.1 - 0.076 12.9 0.0 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ank_2 PF12796.2 CEP18524.1 - 2.1e-25 88.8 14.0 1e-06 28.9 0.0 4.8 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 CEP18524.1 - 3.3e-20 70.7 18.1 0.0002 20.9 0.9 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 CEP18524.1 - 1.3e-18 65.1 12.4 0.0023 18.0 0.2 8.1 7 0 0 7 7 7 5 Ankyrin repeat VPS9 PF02204.13 CEP18524.1 - 5.8e-16 58.4 0.0 2.1e-15 56.5 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.1 CEP18524.1 - 5.9e-16 58.4 11.3 0.00019 21.8 0.0 6.2 4 2 3 7 7 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP18524.1 - 2.2e-13 49.9 17.7 0.0015 18.7 0.1 7.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) PX PF00787.19 CEP18524.1 - 0.027 14.2 0.7 0.16 11.7 0.5 2.3 1 1 0 1 1 1 0 PX domain Pkinase PF00069.20 CEP18525.1 - 2.3e-51 174.4 0.0 3.2e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18525.1 - 1.6e-28 99.4 0.0 2.3e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP18525.1 - 2.4e-05 23.4 0.0 3.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP18525.1 - 0.0018 18.0 0.4 0.0029 17.3 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CEP18525.1 - 0.0084 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CEP18525.1 - 0.032 13.0 0.2 0.048 12.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FtsJ PF01728.14 CEP18526.1 - 3.6e-56 190.0 0.0 5.7e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NTP_transf_2 PF01909.18 CEP18526.1 - 7.5e-11 42.2 0.0 2.1e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CEP18526.1 - 7.3e-10 38.6 0.8 2e-09 37.2 0.1 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase Methyltransf_31 PF13847.1 CEP18526.1 - 0.00026 20.6 0.0 0.0024 17.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP18526.1 - 0.01 15.8 0.0 0.034 14.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain zf-RVT PF13966.1 CEP18527.1 - 4.5e-08 33.2 0.7 7.9e-08 32.5 0.5 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Troponin-I_N PF11636.3 CEP18528.1 - 0.032 13.9 0.5 0.051 13.2 0.4 1.3 1 0 0 1 1 1 0 Troponin I residues 1-32 HTH_Tnp_1 PF01527.15 CEP18529.1 - 0.0091 15.9 0.2 0.019 14.9 0.2 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP18529.1 - 0.077 13.1 0.1 0.22 11.7 0.0 1.8 2 1 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.1 CEP18529.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain VID27 PF08553.5 CEP18529.1 - 0.24 9.5 8.3 0.29 9.3 5.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DAO PF01266.19 CEP18531.1 - 1e-09 37.8 0.0 1.2e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CEP18531.1 - 0.0028 16.5 0.0 0.0035 16.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 CEP18531.1 - 0.032 14.1 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP18531.1 - 0.078 13.0 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LysM PF01476.15 CEP18532.1 - 2.9e-06 27.0 0.0 7.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 LysM domain PGI PF00342.14 CEP18533.1 - 7.5e-234 776.5 0.7 1e-233 776.1 0.5 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase MAF_flag10 PF01973.13 CEP18533.1 - 0.0083 15.6 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF115 PI3_PI4_kinase PF00454.22 CEP18534.1 - 2.2e-29 102.5 0.0 8.4e-29 100.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 CEP18534.1 - 6.5e-11 41.8 0.0 1.8e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 CEP18534.1 - 0.00013 21.1 0.1 0.00029 20.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RVT_1 PF00078.22 CEP18535.1 - 0.0034 16.7 0.8 0.011 15.0 0.6 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 CEP18536.1 - 2.1e-24 85.9 0.0 3e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP18536.1 - 0.048 13.7 0.0 0.34 11.0 0.0 2.1 2 1 0 2 2 2 0 Integrase core domain SRF-TF PF00319.13 CEP18536.1 - 0.17 11.1 5.8 0.23 10.6 0.0 2.9 3 0 0 3 3 3 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Chromo PF00385.19 CEP18537.1 - 0.028 14.1 0.2 0.06 13.0 0.2 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF4180 PF13788.1 CEP18537.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) rve PF00665.21 CEP18537.1 - 0.069 13.2 0.0 0.39 10.8 0.0 2.0 1 1 0 1 1 1 0 Integrase core domain CLASP_N PF12348.3 CEP18537.1 - 0.11 11.7 0.2 0.23 10.7 0.1 1.5 1 0 0 1 1 1 0 CLASP N terminal Aldo_ket_red PF00248.16 CEP18540.1 - 1.1e-06 27.6 0.0 1.3e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S5 PF00333.15 CEP18540.1 - 0.057 13.1 0.0 5.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Transposase_21 PF02992.9 CEP18541.1 - 3.4e-05 23.0 0.0 6.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CEP18541.1 - 0.047 13.1 3.0 0.072 12.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Rpr2 PF04032.11 CEP18541.1 - 0.081 12.8 0.3 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Chromo PF00385.19 CEP18547.1 - 0.0019 17.8 1.2 0.0034 17.0 0.2 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Zn_Tnp_IS1595 PF12760.2 CEP18548.1 - 0.4 10.5 7.7 1.8 8.4 0.5 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Exo_endo_phos PF03372.18 CEP18550.1 - 2.8e-05 24.1 0.0 3.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP18550.1 - 0.0043 16.6 0.1 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Asp_protease_2 PF13650.1 CEP18551.1 - 2.2e-05 24.8 0.0 4.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Pepsin-I3 PF06394.8 CEP18551.1 - 0.00033 20.2 0.0 0.00073 19.1 0.0 1.6 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain Asp_protease PF09668.5 CEP18551.1 - 0.0095 15.5 0.2 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 CEP18551.1 - 0.051 13.1 0.5 0.26 10.8 0.0 2.0 1 1 1 2 2 2 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.1 CEP18551.1 - 0.059 13.2 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF4301 PF14134.1 CEP18552.1 - 0.048 12.2 0.1 0.06 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) CENP-Q PF13094.1 CEP18553.1 - 0.00043 20.3 8.7 0.00095 19.2 6.0 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF3133 PF11331.3 CEP18553.1 - 0.12 11.9 2.8 0.9 9.1 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) IncA PF04156.9 CEP18553.1 - 0.22 11.0 3.6 0.42 10.1 2.5 1.4 1 0 0 1 1 1 0 IncA protein RVT_1 PF00078.22 CEP18554.1 - 8.2e-15 54.7 0.0 3.4e-14 52.7 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP18557.1 - 1.4e-05 25.1 0.0 1.9e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNB PF00773.14 CEP18558.1 - 8.5e-78 261.8 0.6 8.5e-78 261.8 0.4 2.7 3 0 0 3 3 3 1 RNB domain OB_RNB PF08206.6 CEP18558.1 - 0.0049 16.3 0.4 0.012 15.0 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease B OB domain DUF1528 PF07515.6 CEP18559.1 - 0.016 15.2 0.2 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) Pathogen_betaC1 PF09593.5 CEP18559.1 - 0.036 13.7 0.1 0.18 11.4 0.0 1.8 1 1 1 2 2 2 0 Beta-satellite pathogenicity beta C1 protein RWD PF05773.17 CEP18559.1 - 0.038 13.9 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 RWD domain Ribosomal_S3_C PF00189.15 CEP18560.1 - 2.6e-08 33.9 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Daxx PF03344.10 CEP18561.1 - 2.8 6.3 8.4 2.9 6.2 5.8 1.0 1 0 0 1 1 1 0 Daxx Family zf-CCHC_4 PF14392.1 CEP18562.1 - 0.0013 18.3 11.0 0.068 12.8 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 CEP18562.1 - 0.044 13.7 1.1 0.044 13.7 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle SR-25 PF10500.4 CEP18563.1 - 0.24 10.8 17.6 0.061 12.7 2.2 2.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Borrelia_P83 PF05262.6 CEP18563.1 - 1 7.5 7.3 1.8 6.7 5.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF844 PF05815.6 CEP18563.1 - 1 8.1 4.0 0.84 8.4 1.7 1.6 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Peptidase_S49_N PF08496.5 CEP18563.1 - 1.5 8.5 5.6 12 5.7 1.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-C3HC4_3 PF13920.1 CEP18564.1 - 0.00073 19.1 3.6 0.00073 19.1 2.5 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP18564.1 - 0.001 19.0 5.5 0.001 19.0 3.8 4.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP18564.1 - 0.0011 18.7 4.5 0.0011 18.7 3.1 4.0 4 1 0 4 4 4 1 Ring finger domain IBR PF01485.16 CEP18564.1 - 0.0018 18.0 1.1 0.0018 18.0 0.7 4.5 4 0 0 4 4 4 2 IBR domain zf-RING_6 PF14835.1 CEP18564.1 - 0.095 12.5 4.1 0.069 12.9 0.8 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CEP18564.1 - 9.3 6.0 31.0 0.023 14.4 3.3 4.2 4 0 0 4 4 4 0 zinc-RING finger domain Sporozoite_P67 PF05642.6 CEP18565.1 - 0.047 11.5 3.7 0.052 11.4 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VID27 PF08553.5 CEP18565.1 - 0.16 10.1 5.8 0.18 10.0 4.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nucleoplasmin PF03066.10 CEP18565.1 - 3.5 7.1 9.3 0.18 11.3 2.6 1.7 2 0 0 2 2 2 0 Nucleoplasmin Dickkopf_N PF04706.7 CEP18566.1 - 0.016 15.3 7.8 0.026 14.6 5.4 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region WBP-1 PF11669.3 CEP18566.1 - 0.042 13.9 0.8 0.1 12.7 0.5 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 PspB PF06667.7 CEP18566.1 - 0.046 13.6 0.3 0.076 12.9 0.2 1.3 1 0 0 1 1 1 0 Phage shock protein B gpUL132 PF11359.3 CEP18566.1 - 0.07 12.4 2.1 0.072 12.4 0.4 1.7 1 1 1 2 2 2 0 Glycoprotein UL132 PrgH PF09480.5 CEP18566.1 - 0.091 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) EB PF01683.13 CEP18566.1 - 0.33 11.0 8.1 0.63 10.1 5.6 1.5 1 0 0 1 1 1 0 EB module MgrB PF13998.1 CEP18566.1 - 0.44 10.3 2.8 1.2 8.9 1.9 1.7 1 1 0 1 1 1 0 MgrB protein GHMP_kinases_N PF00288.21 CEP18567.1 - 1.2e-14 54.0 0.1 3e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CEP18567.1 - 0.00039 20.5 0.0 0.00094 19.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF2365 PF10157.4 CEP18568.1 - 0.15 11.9 0.5 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) zf-RVT PF13966.1 CEP18569.1 - 0.002 18.3 0.9 0.002 18.3 0.6 1.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase CRISPR_Cas2 PF09827.4 CEP18570.1 - 0.042 13.9 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 CRISPR associated protein Cas2 tRNA-synt_1 PF00133.17 CEP18571.1 - 1.3e-222 740.1 1.4 1.3e-222 740.1 1.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CEP18571.1 - 9.6e-27 93.6 1.9 2.1e-26 92.5 0.0 2.4 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CEP18571.1 - 4e-19 68.5 3.2 1.6e-09 36.9 0.3 4.7 3 2 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CEP18571.1 - 0.00022 20.4 0.1 0.0051 15.9 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain WD40 PF00400.27 CEP18572.1 - 4.1e-22 77.1 0.1 6.7e-07 28.9 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat CPSF_A PF03178.10 CEP18572.1 - 0.0059 15.7 0.0 0.88 8.5 0.0 2.2 2 0 0 2 2 2 2 CPSF A subunit region Nup160 PF11715.3 CEP18572.1 - 0.023 12.8 0.3 0.11 10.6 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Utp11 PF03998.8 CEP18573.1 - 2e-67 227.5 30.1 2.2e-67 227.4 20.8 1.0 1 0 0 1 1 1 1 Utp11 protein DUF4164 PF13747.1 CEP18573.1 - 0.0079 16.3 1.8 0.0079 16.3 1.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) Lipoprotein_20 PF13942.1 CEP18573.1 - 0.061 12.8 3.4 0.14 11.6 2.4 1.5 1 0 0 1 1 1 0 YfhG lipoprotein GTSE1_N PF15259.1 CEP18573.1 - 0.29 11.0 7.7 1.3 8.9 5.1 2.1 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 PAS_10 PF13596.1 CEP18573.1 - 0.46 10.7 3.0 1.1 9.5 0.2 2.8 3 1 0 3 3 3 0 PAS domain DUF3808 PF10300.4 CEP18575.1 - 1e-69 235.3 5.5 1.9e-69 234.4 3.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 CEP18575.1 - 0.0031 17.3 0.5 1.2 9.2 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat SR-25 PF10500.4 CEP18576.1 - 2.8 7.3 14.1 0.11 11.9 1.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2962 PF11176.3 CEP18577.1 - 1.3e-37 128.7 6.7 1.7e-37 128.3 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF2072 PF09845.4 CEP18577.1 - 0.012 15.5 0.6 0.012 15.5 0.4 1.7 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Acyltransferase PF01553.16 CEP18578.1 - 3.5e-13 49.1 0.1 1.6e-11 43.7 0.1 2.4 1 1 0 1 1 1 1 Acyltransferase Rtt106 PF08512.7 CEP18579.1 - 8.2e-21 73.7 0.0 2.2e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like NAD_binding_7 PF13241.1 CEP18580.1 - 2.1e-17 63.2 0.1 3.3e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CEP18580.1 - 6.6e-12 44.5 0.0 1.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CEP18580.1 - 0.00045 19.1 0.1 0.0011 17.8 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pdase_C33_assoc PF14756.1 CEP18580.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase_C33-associated domain NifU_N PF01592.11 CEP18580.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NifU-like N terminal domain DUF3814 PF12769.2 CEP18581.1 - 0.21 11.7 0.9 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) AhpC-TSA PF00578.16 CEP18582.1 - 1.3e-33 115.3 0.0 1.7e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CEP18582.1 - 1.7e-15 56.3 0.1 3.9e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CEP18582.1 - 8.5e-13 48.0 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin CBS PF00571.23 CEP18583.1 - 7.7e-08 32.0 0.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 CBS domain BRE1 PF08647.6 CEP18584.1 - 3e-07 30.3 12.2 3e-07 30.3 8.5 6.6 6 1 1 7 7 7 1 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.7 CEP18584.1 - 0.18 11.6 15.6 0.68 9.7 0.1 4.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_IE-1 PF05290.6 CEP18584.1 - 1.3 8.7 5.3 4.4 7.0 0.3 3.0 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) UCR_14kD PF02271.11 CEP18585.1 - 9.5e-37 124.9 0.3 1.1e-36 124.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.6 CEP18585.1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 She9 / Mdm33 family Dpoe2NT PF12213.3 CEP18586.1 - 0.063 13.1 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal Helitron_like_N PF14214.1 CEP18587.1 - 5.8e-35 120.6 0.0 6.6e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus LRR_8 PF13855.1 CEP18590.1 - 0.0039 16.9 3.9 2.2 8.0 0.0 4.0 3 2 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CEP18590.1 - 0.0068 16.3 0.7 2.3 8.5 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 CEP18590.1 - 0.2 11.8 1.0 11 6.5 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CEP18590.1 - 1.8 9.1 7.4 37 5.1 0.0 5.2 6 1 0 6 6 6 0 Leucine rich repeat DUF605 PF04652.11 CEP18591.1 - 0.22 10.8 8.1 0.031 13.6 2.2 1.8 2 0 0 2 2 2 0 Vta1 like APC_CDC26 PF10471.4 CEP18591.1 - 0.27 12.0 0.0 0.27 12.0 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF2890 PF11081.3 CEP18591.1 - 1.3 9.0 12.6 0.2 11.6 5.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) RasGEF PF00617.14 CEP18592.1 - 1.8e-47 161.5 0.2 2.9e-47 160.8 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEP18592.1 - 1.2e-11 44.6 3.0 1.4e-11 44.3 0.5 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.17 CEP18592.1 - 2e-06 27.3 0.0 3.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP18592.1 - 0.1 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Response_reg PF00072.19 CEP18593.1 - 5.5e-22 77.8 0.1 1.1e-14 54.3 0.0 2.8 2 1 0 2 2 2 2 Response regulator receiver domain Sigma70_ner PF04546.8 CEP18594.1 - 0.0084 15.7 0.6 0.0084 15.7 0.4 1.4 2 0 0 2 2 2 1 Sigma-70, non-essential region DNA_binding_2 PF13724.1 CEP18595.1 - 1.8 8.7 5.2 0.44 10.7 1.5 1.5 2 0 0 2 2 2 0 DNA-binding domain PIF1 PF05970.9 CEP18596.1 - 4.3e-68 229.9 0.0 1.2e-45 156.0 0.0 2.0 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 CEP18596.1 - 0.0029 15.4 0.2 0.004 14.9 0.2 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP18596.1 - 0.0087 16.1 0.0 0.024 14.7 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Beta_helix PF13229.1 CEP18597.1 - 0.014 15.1 8.9 0.04 13.6 6.2 1.8 1 1 0 1 1 1 0 Right handed beta helix region DUF2703 PF10865.3 CEP18597.1 - 0.16 11.9 3.6 0.24 11.3 1.3 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF2703) MukB PF04310.7 CEP18597.1 - 0.68 9.2 6.6 0.42 9.8 2.7 1.8 1 1 1 2 2 2 0 MukB N-terminal Fim-adh_lectin PF09222.5 CEP18597.1 - 1.8 7.8 5.8 0.43 9.8 1.9 1.6 1 1 1 2 2 2 0 Fimbrial adhesin F17-AG, lectin domain Ribosomal_S28e PF01200.13 CEP18597.1 - 2.3 8.0 4.6 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein S28e Toxin_30 PF08117.6 CEP18599.1 - 0.06 13.3 1.3 5.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Ptu family GATA-N PF05349.7 CEP18601.1 - 0.63 10.1 4.8 4.5 7.4 3.3 2.2 1 1 0 1 1 1 0 GATA-type transcription activator, N-terminal IF-2B PF01008.12 CEP18603.1 - 1.2e-64 218.0 3.0 3.8e-64 216.4 2.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family APG6 PF04111.7 CEP18604.1 - 9.1e-124 412.5 7.7 1.2e-123 412.1 5.4 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 BH3 PF15285.1 CEP18604.1 - 0.032 13.7 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting AAA_23 PF13476.1 CEP18604.1 - 0.054 13.8 7.9 0.11 12.7 5.5 1.5 1 0 0 1 1 1 0 AAA domain Ad_cyc_g-alpha PF08509.6 CEP18604.1 - 0.28 10.5 1.7 0.77 9.1 0.2 2.2 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain V_ATPase_I PF01496.14 CEP18604.1 - 0.35 8.6 5.6 0.49 8.1 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 CEP18604.1 - 2.6 7.9 14.3 5.4 6.9 9.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 CEP18604.1 - 6.5 6.8 16.1 0.62 10.1 7.8 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain EAP30 PF04157.11 CEP18605.1 - 3.2e-61 206.3 0.1 3.6e-61 206.1 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_Mu_Gam PF07352.7 CEP18605.1 - 0.019 14.5 0.4 0.019 14.5 0.3 1.6 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF1269 PF06897.7 CEP18605.1 - 0.12 12.3 0.1 0.64 10.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Mem_trans PF03547.13 CEP18606.1 - 9.4e-46 155.8 9.7 1.4e-45 155.2 6.7 1.3 1 0 0 1 1 1 1 Membrane transport protein G-alpha PF00503.15 CEP18607.1 - 5e-119 397.4 3.1 6e-119 397.2 2.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP18607.1 - 1.2e-12 47.4 2.9 8.3e-08 31.6 0.0 2.5 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP18607.1 - 0.0014 17.7 4.0 0.031 13.4 0.1 2.6 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP18607.1 - 0.0049 17.3 0.1 4 7.9 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 CEP18607.1 - 0.0074 15.7 0.1 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 CEP18607.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PMT PF02366.13 CEP18608.1 - 1.1e-82 277.1 21.6 1.1e-82 277.1 15.0 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEP18608.1 - 9.3e-35 119.8 1.3 9.3e-35 119.8 0.9 1.5 2 0 0 2 2 2 1 MIR domain RVT_1 PF00078.22 CEP18609.1 - 6.3e-21 74.7 0.9 1.2e-20 73.8 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP18609.1 - 2e-07 31.2 1.0 4.2e-07 30.1 0.7 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Cation_efflux PF01545.16 CEP18610.1 - 1.5e-75 253.8 13.0 1.8e-75 253.6 9.0 1.0 1 0 0 1 1 1 1 Cation efflux family TMEM141 PF15110.1 CEP18610.1 - 0.057 13.7 2.1 0.15 12.4 0.1 2.5 3 0 0 3 3 3 0 TMEM141 protein family CD20 PF04103.10 CEP18610.1 - 0.45 10.4 5.1 1.4 8.8 0.9 3.1 1 1 2 3 3 3 0 CD20-like family DUF4212 PF13937.1 CEP18610.1 - 0.53 10.3 2.6 0.87 9.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) ETRAMP PF09716.5 CEP18610.1 - 0.64 10.0 5.3 1 9.3 0.4 3.1 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF1980 PF09323.5 CEP18610.1 - 6.7 6.4 6.0 2 8.1 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) FGGY_N PF00370.16 CEP18611.1 - 7.7e-68 228.4 0.0 1.1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CEP18611.1 - 1.6e-66 223.7 1.0 4.8e-66 222.1 0.4 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CEP18611.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family SBDS PF01172.13 CEP18612.1 - 3.6e-16 58.7 0.5 4.3e-16 58.4 0.4 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Transthyretin PF00576.16 CEP18613.1 - 1.1e-35 121.9 0.0 1.3e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Complex1_LYR PF05347.10 CEP18614.1 - 3.5e-11 42.7 2.3 5.5e-11 42.1 1.6 1.3 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEP18614.1 - 1.5e-09 37.8 0.4 2e-09 37.5 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CEP18614.1 - 0.2 12.1 1.0 0.28 11.6 0.7 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Chromo PF00385.19 CEP18616.1 - 2.8e-12 46.0 3.2 2.8e-12 46.0 2.2 2.2 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CEP18616.1 - 0.11 12.4 0.8 2.5 7.9 0.1 2.6 2 1 0 2 2 2 0 Chromo shadow domain CK_II_beta PF01214.13 CEP18617.1 - 3.9e-75 251.3 0.0 6.2e-75 250.7 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit NTP_transferase PF00483.18 CEP18617.1 - 9.7e-27 93.8 0.0 1.6e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CEP18617.1 - 9.1e-10 37.5 10.2 6.7e-07 28.5 0.3 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CEP18617.1 - 4.7e-07 30.0 0.0 7.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CEP18617.1 - 0.022 14.3 1.5 0.12 11.9 0.6 2.3 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase LIM PF00412.17 CEP18618.1 - 5.1e-33 112.9 53.7 1.4e-11 44.3 5.2 5.2 5 0 0 5 5 5 4 LIM domain Fer4_21 PF14697.1 CEP18618.1 - 0.046 13.5 0.9 0.046 13.5 0.6 4.5 5 1 1 6 6 6 0 4Fe-4S dicluster domain SNARE PF05739.14 CEP18619.1 - 1.5e-18 66.2 6.2 1.5e-18 66.2 4.3 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CEP18619.1 - 7.4e-11 42.1 4.4 7.4e-11 42.1 3.0 2.6 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 CEP18619.1 - 0.00074 19.5 6.7 0.00074 19.5 4.7 2.7 2 1 0 2 2 2 1 Syntaxin-like protein Vac_Fusion PF02346.11 CEP18619.1 - 0.0041 16.5 0.8 0.0041 16.5 0.5 3.0 3 1 0 3 3 3 1 Chordopoxvirus fusion protein YfdX PF10938.3 CEP18619.1 - 0.016 14.9 0.9 0.042 13.5 0.7 1.6 1 0 0 1 1 1 0 YfdX protein DUF4094 PF13334.1 CEP18619.1 - 0.028 14.8 0.5 0.028 14.8 0.3 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4094) MCPsignal PF00015.16 CEP18619.1 - 0.08 12.4 18.2 0.018 14.5 4.6 2.8 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1525 PF07511.6 CEP18619.1 - 0.34 10.8 0.1 0.34 10.8 0.0 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1525) Tht1 PF04163.7 CEP18619.1 - 1.9 6.8 10.4 0.091 11.1 2.9 1.7 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein PspA_IM30 PF04012.7 CEP18619.1 - 4.5 6.5 15.3 8 5.7 5.8 2.5 1 1 1 2 2 2 0 PspA/IM30 family Med28 PF11594.3 CEP18619.1 - 5.2 7.3 15.8 0.11 12.7 0.4 3.4 2 1 1 3 3 3 0 Mediator complex subunit 28 SUI1 PF01253.17 CEP18620.1 - 4.4e-21 74.4 0.4 9.5e-21 73.4 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 BAR_2 PF10455.4 CEP18620.1 - 0.021 13.7 2.9 0.036 12.9 1.8 1.5 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Acylphosphatase PF00708.13 CEP18620.1 - 0.027 14.5 2.2 0.032 14.3 0.3 1.9 1 1 0 2 2 2 0 Acylphosphatase DDE_3 PF13358.1 CEP18623.1 - 2.2e-16 59.9 0.0 2.5e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SOR_SNZ PF01680.12 CEP18624.1 - 3.8e-116 385.9 5.2 3.8e-116 385.9 3.6 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 CEP18624.1 - 9.9e-10 37.9 7.3 2.2e-07 30.2 0.2 2.5 2 2 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 CEP18624.1 - 0.00033 19.6 0.6 0.69 8.6 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 CEP18624.1 - 0.00046 19.2 0.2 0.11 11.5 0.0 2.5 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 CEP18624.1 - 0.0073 15.5 0.6 0.21 10.8 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 CEP18624.1 - 0.013 14.5 0.4 0.059 12.4 0.0 2.3 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.12 CEP18624.1 - 0.072 12.2 0.5 2.3 7.2 0.0 2.7 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI NMO PF03060.10 CEP18624.1 - 0.12 11.4 4.6 0.092 11.8 0.1 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase DUF2404 PF10296.4 CEP18625.1 - 1.9e-06 27.9 0.0 3.6e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) NUDIX_4 PF14815.1 CEP18625.1 - 0.021 14.2 1.2 0.053 12.9 0.1 2.1 2 0 0 2 2 2 0 NUDIX domain Y_phosphatase PF00102.22 CEP18626.1 - 4.5e-66 222.5 2.8 1.2e-65 221.2 2.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CEP18626.1 - 8.1e-13 48.7 0.0 4.7e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Gastrin PF00918.12 CEP18626.1 - 0.017 15.9 0.1 0.094 13.5 0.0 2.2 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DSPc PF00782.15 CEP18626.1 - 0.018 14.6 0.1 0.051 13.1 0.1 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CEP18626.1 - 0.049 13.8 0.2 0.38 10.9 0.1 2.4 2 0 0 2 2 2 0 Tyrosine phosphatase family NAD_binding_10 PF13460.1 CEP18629.1 - 5.7e-06 26.4 0.0 7.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEP18629.1 - 1.1e-05 24.8 0.0 1.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Ribosomal_S8 PF00410.14 CEP18630.1 - 4.1e-27 94.5 0.0 5.2e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 LSM PF01423.17 CEP18631.1 - 1.5e-11 43.6 0.0 1.8e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Glucan_synthase PF02364.10 CEP18632.1 - 0 1159.5 12.9 6.7e-195 649.4 5.3 2.2 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CEP18632.1 - 7.5e-35 119.3 0.2 1.9e-34 118.0 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Methyltransf_31 PF13847.1 CEP18633.1 - 1.1e-11 44.5 2.0 6.7e-11 41.9 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CEP18633.1 - 1.8e-11 43.7 2.2 3.5e-11 42.7 0.0 2.3 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 CEP18633.1 - 1.6e-10 41.2 1.1 3.1e-09 37.1 0.0 3.1 3 1 1 4 4 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP18633.1 - 4.1e-09 36.9 0.1 2.6e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 CEP18633.1 - 1.7e-08 33.8 0.1 2.2e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 CEP18633.1 - 8.4e-08 32.2 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP18633.1 - 1.2e-07 31.2 0.1 2.3e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain zf-C2H2_2 PF12756.2 CEP18633.1 - 2.8e-06 27.3 2.3 8.3e-06 25.8 0.9 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Methyltransf_23 PF13489.1 CEP18633.1 - 2e-05 24.3 0.4 0.0001 22.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP18633.1 - 6.7e-05 23.1 0.0 0.00031 21.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP18633.1 - 7.2e-05 23.1 1.6 0.00024 21.5 0.0 2.7 4 0 0 4 4 3 1 Methyltransferase domain PCMT PF01135.14 CEP18633.1 - 0.00089 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 CEP18633.1 - 0.0019 17.6 0.1 0.0051 16.2 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 CEP18633.1 - 0.0019 17.8 0.1 0.0042 16.6 0.1 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.9 CEP18633.1 - 0.0062 15.7 0.1 0.013 14.6 0.1 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 CEP18633.1 - 0.011 14.5 0.2 0.022 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) FtsJ PF01728.14 CEP18633.1 - 0.082 12.8 0.2 0.22 11.4 0.1 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Cons_hypoth95 PF03602.10 CEP18633.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DNA_pol_E_B PF04042.11 CEP18634.1 - 4.7e-38 130.5 1.4 8.9e-38 129.6 1.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 CEP18634.1 - 2e-10 40.6 2.8 3.3e-10 39.9 1.9 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal ATP-synt_ab_C PF00306.22 CEP18634.1 - 0.029 14.8 0.1 0.19 12.1 0.0 2.4 3 1 0 3 3 3 0 ATP synthase alpha/beta chain, C terminal domain LAMTOR PF15454.1 CEP18635.1 - 3.8e-05 23.8 3.4 3.8e-05 23.8 2.3 1.8 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator NIF PF03031.13 CEP18637.1 - 2.7e-37 127.8 0.2 5e-37 127.0 0.0 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase YjeF_N PF03853.10 CEP18638.1 - 5.2e-30 104.2 1.2 2e-29 102.3 0.0 2.3 2 0 0 2 2 2 1 YjeF-related protein N-terminus LSM PF01423.17 CEP18638.1 - 5e-05 22.7 0.5 9.3e-05 21.9 0.3 1.4 1 0 0 1 1 1 1 LSM domain ACR_tran PF00873.14 CEP18638.1 - 0.061 10.7 3.7 0.13 9.6 2.6 1.5 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Pep3_Vps18 PF05131.9 CEP18639.1 - 4.4e-42 143.0 0.9 8.4e-42 142.0 0.3 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CEP18639.1 - 7.9e-06 25.5 6.5 2.7e-05 23.7 0.5 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 CEP18639.1 - 0.0019 17.9 3.2 0.0019 17.9 2.2 2.3 2 0 0 2 2 2 1 Ring finger domain Vps39_2 PF10367.4 CEP18639.1 - 0.0022 18.1 0.3 0.0022 18.1 0.2 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 CEP18639.1 - 0.0032 17.4 0.5 0.017 15.2 0.4 2.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-rbx1 PF12678.2 CEP18639.1 - 0.052 13.6 0.4 0.16 12.0 0.3 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 CEP18639.1 - 0.17 11.6 3.9 0.8 9.4 2.7 2.2 1 1 0 1 1 1 0 zinc-RING finger domain TPR_8 PF13181.1 CEP18639.1 - 0.2 11.5 3.4 3 7.8 1.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEP18639.1 - 0.25 11.0 9.0 1.9 8.2 2.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP18639.1 - 0.99 9.3 4.2 38 4.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 CEP18639.1 - 3 7.5 6.9 0.47 10.1 1.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RasGAP PF00616.14 CEP18640.1 - 1.1e-54 185.1 0.0 3.4e-54 183.5 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CEP18640.1 - 9.4e-31 106.4 0.5 9.4e-31 106.4 0.3 2.3 3 0 0 3 3 3 1 RasGAP C-terminus RNase_PH PF01138.16 CEP18640.1 - 2.6e-25 89.2 0.7 5.3e-25 88.2 0.1 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CEP18640.1 - 9e-06 25.5 0.0 2.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MitMem_reg PF13012.1 CEP18640.1 - 0.021 14.9 0.9 0.021 14.9 0.6 3.2 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function WXG100 PF06013.7 CEP18640.1 - 0.049 13.6 0.3 0.55 10.2 0.1 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF309 PF03745.9 CEP18640.1 - 0.25 10.8 1.2 0.4 10.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF309) DUF972 PF06156.8 CEP18640.1 - 0.36 11.1 9.0 3.6 7.9 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF2300 PF10062.4 CEP18641.1 - 0.062 13.0 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) CARDB PF07705.6 CEP18642.1 - 0.12 12.4 0.1 0.2 11.7 0.1 1.6 1 1 0 1 1 1 0 CARDB UPF0172 PF03665.8 CEP18643.1 - 7.6e-43 146.2 0.0 9.4e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 CEP18643.1 - 0.00019 21.1 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CEP18643.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Lectin_leg-like PF03388.8 CEP18644.1 - 7e-60 202.0 0.1 9.6e-60 201.5 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family HAUS4 PF14735.1 CEP18644.1 - 0.0044 16.3 2.1 0.0044 16.3 1.5 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 DUF1993 PF09351.5 CEP18644.1 - 0.038 13.9 0.6 0.038 13.9 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Cortex-I_coil PF09304.5 CEP18644.1 - 2.5 8.2 11.0 10 6.2 3.1 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil BLOC1_2 PF10046.4 CEP18644.1 - 3.1 7.9 8.7 0.25 11.4 1.9 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-B_box PF00643.19 CEP18645.1 - 0.6 10.0 7.5 0.96 9.3 3.3 2.4 2 1 0 2 2 2 0 B-box zinc finger MAGE_N PF12440.3 CEP18645.1 - 4.1 7.7 9.0 2.2 8.6 2.1 2.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal RNHCP PF12647.2 CEP18646.1 - 0.079 12.8 0.6 0.48 10.2 0.1 2.1 1 1 1 2 2 2 0 RNHCP domain DUF3818 PF12825.2 CEP18647.1 - 1.6e-72 244.0 13.8 7.2e-72 241.9 9.6 2.0 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CEP18647.1 - 2.1e-14 53.2 3.2 6.4e-13 48.4 2.2 3.0 1 1 0 1 1 1 1 PX-associated PX PF00787.19 CEP18647.1 - 2.7e-08 33.5 1.4 1.6e-07 31.0 0.9 2.4 1 1 0 1 1 1 1 PX domain bZIP_1 PF00170.16 CEP18647.1 - 0.46 10.4 9.7 0.031 14.2 2.1 2.6 2 0 0 2 2 2 0 bZIP transcription factor SMC_Nse1 PF07574.8 CEP18647.1 - 0.91 9.1 7.7 0.44 10.1 0.2 3.0 3 0 0 3 3 3 0 Nse1 non-SMC component of SMC5-6 complex HTH_23 PF13384.1 CEP18648.1 - 1.7e-06 27.4 0.0 5.8e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Myb_DNA-bind_6 PF13921.1 CEP18648.1 - 0.00052 20.0 0.1 0.0016 18.5 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_29 PF13551.1 CEP18648.1 - 0.0032 17.6 0.0 0.0088 16.1 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.1 CEP18648.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_28 PF13518.1 CEP18648.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GluR_Homer-bdg PF10606.4 CEP18648.1 - 2.2 8.2 5.7 16 5.4 2.3 2.7 3 0 0 3 3 3 0 Homer-binding domain of metabotropic glutamate receptor WD40 PF00400.27 CEP18649.1 - 7e-13 47.9 11.6 1.6e-05 24.6 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat CPSF_A PF03178.10 CEP18649.1 - 0.00082 18.5 0.1 0.036 13.1 0.0 2.2 1 1 1 2 2 2 2 CPSF A subunit region Tetraspannin PF00335.15 CEP18650.1 - 3.5e-09 36.2 6.3 4.8e-09 35.8 4.4 1.2 1 0 0 1 1 1 1 Tetraspanin family Pdase_C33_assoc PF14756.1 CEP18650.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase_C33-associated domain Kei1 PF08552.6 CEP18650.1 - 0.087 12.4 2.3 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 FixQ PF05545.6 CEP18650.1 - 0.29 10.7 1.9 0.38 10.4 0.4 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ La PF05383.12 CEP18651.1 - 8.5e-22 76.7 0.0 2.1e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 La domain E1-E2_ATPase PF00122.15 CEP18652.1 - 4.8e-75 251.5 2.8 2.3e-74 249.3 0.2 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP18652.1 - 1.8e-48 164.5 6.4 1.8e-48 164.5 4.5 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP18652.1 - 9.8e-31 107.8 0.0 7.4e-30 104.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP18652.1 - 4.4e-17 61.8 0.0 9.6e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP18652.1 - 8.2e-16 58.7 0.0 5.4e-15 56.0 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP18652.1 - 8.9e-16 57.1 0.0 1.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP18652.1 - 3.4e-06 26.8 3.6 0.0024 17.4 1.3 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP18652.1 - 0.046 13.9 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CEP18652.1 - 0.1 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase adh_short PF00106.20 CEP18653.1 - 1.2e-18 67.5 0.0 2.8e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP18653.1 - 1.2e-07 31.8 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP18653.1 - 5.9e-07 29.3 0.0 8.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CEP18653.1 - 0.011 15.1 0.1 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEP18653.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CEP18653.1 - 0.085 12.6 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_47 PF01532.15 CEP18654.1 - 5.7e-135 450.4 1.4 6.8e-135 450.2 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 CEP18654.1 - 0.012 13.9 0.0 2.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) DUF1713 PF08213.6 CEP18655.1 - 5.7e-15 54.6 19.0 8.8e-15 54.0 13.2 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Ribosomal_S13 PF00416.17 CEP18656.1 - 8.6e-30 103.3 0.2 1e-29 103.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CEP18656.1 - 0.0048 15.4 0.0 0.0051 15.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) adh_short PF00106.20 CEP18657.1 - 3.4e-14 53.1 0.0 4.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CEP18657.1 - 8.1e-06 25.4 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEP18657.1 - 9.8e-05 22.4 0.0 0.00019 21.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CEP18657.1 - 0.00014 21.6 0.0 0.00028 20.5 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CEP18657.1 - 0.00051 19.8 0.0 0.00072 19.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CEP18657.1 - 0.06 12.2 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPGT PF00201.13 CEP18658.1 - 6.3e-24 84.3 0.0 2.9e-23 82.1 0.0 2.0 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CEP18658.1 - 1.1e-09 38.1 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CEP18658.1 - 4.6e-07 29.3 0.0 2.6e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 DUF3899 PF13038.1 CEP18658.1 - 0.0062 16.6 0.1 2 8.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3899) Fibrinogen_aC PF12160.3 CEP18659.1 - 0.022 14.2 2.7 1.4 8.4 0.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha C domain AdoHcyase PF05221.12 CEP18660.1 - 1.1e-140 467.1 0.0 1.3e-140 466.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CEP18660.1 - 3.2e-87 290.4 2.3 4.8e-87 289.8 1.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CEP18660.1 - 8.7e-10 38.0 0.5 1.6e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CEP18660.1 - 2.7e-05 23.5 0.1 4.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CEP18660.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain TMEM107 PF14995.1 CEP18660.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein FG-GAP PF01839.18 CEP18661.1 - 9.8e-11 41.0 0.6 0.00013 21.5 0.1 3.0 2 0 0 2 2 2 2 FG-GAP repeat Zn_dep_PLPC PF00882.13 CEP18661.1 - 1.7e-09 37.5 1.3 4.6e-09 36.1 0.9 1.6 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.1 CEP18661.1 - 1.4e-05 25.3 1.4 0.00018 21.8 0.7 3.0 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 CEP18661.1 - 0.00072 19.5 0.0 0.011 15.6 0.0 2.9 3 0 0 3 3 3 1 FG-GAP repeat zf-C2H2 PF00096.21 CEP18662.1 - 2.4e-07 30.6 11.2 0.00026 21.1 1.0 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP18662.1 - 1.1e-06 28.6 1.4 1.1e-06 28.6 1.0 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP18662.1 - 5.4e-05 23.2 7.6 0.013 15.8 0.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP18662.1 - 0.061 13.2 1.0 0.39 10.6 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_2 PF12796.2 CEP18663.1 - 5e-23 81.2 16.4 5.7e-08 32.9 1.2 4.4 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEP18663.1 - 2.6e-21 74.3 14.4 0.00084 19.0 0.0 8.9 7 2 2 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 CEP18663.1 - 4e-15 54.4 13.3 0.00018 21.3 0.1 8.9 7 2 3 10 10 10 4 Ankyrin repeat Ank_4 PF13637.1 CEP18663.1 - 2.6e-14 53.2 14.5 8.4e-05 22.9 0.2 6.9 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP18663.1 - 2.2e-09 37.2 17.2 0.0021 18.2 0.1 7.1 2 1 6 8 8 8 2 Ankyrin repeats (many copies) DUF3447 PF11929.3 CEP18663.1 - 7.1e-05 22.5 1.8 0.033 13.9 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) DUF249 PF03158.8 CEP18663.1 - 0.042 13.3 1.4 0.18 11.2 0.3 2.3 1 1 1 2 2 2 0 Multigene family 530 protein Phage_T7_Capsid PF05396.6 CEP18663.1 - 0.081 13.0 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Kei1 PF08552.6 CEP18664.1 - 5.9e-05 22.7 11.0 0.012 15.3 0.4 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 SUR7 PF06687.7 CEP18664.1 - 0.00099 18.7 0.3 0.0012 18.4 0.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF996 PF06195.8 CEP18664.1 - 0.0037 17.2 0.4 0.0056 16.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF996) MFS_2 PF13347.1 CEP18664.1 - 0.053 11.9 0.5 0.059 11.7 0.3 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein PalH PF08733.5 CEP18664.1 - 0.071 11.9 2.5 0.089 11.6 1.8 1.1 1 0 0 1 1 1 0 PalH/RIM21 DUF3169 PF11368.3 CEP18664.1 - 0.15 11.2 3.5 0.33 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DUF1600 PF07667.6 CEP18664.1 - 0.3 11.1 5.6 7.2 6.7 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) PIG-P PF08510.7 CEP18664.1 - 0.4 10.3 3.3 2.5 7.7 0.1 2.1 1 1 1 2 2 2 0 PIG-P zf-DHHC PF01529.15 CEP18664.1 - 0.63 9.4 4.6 1.1 8.6 3.2 1.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase EOS1 PF12326.3 CEP18664.1 - 2.1 7.9 7.0 2.5 7.7 4.1 1.7 1 1 1 2 2 2 0 N-glycosylation protein Rep_fac_C PF08542.6 CEP18665.1 - 2e-18 66.1 0.7 5.2e-18 64.8 0.1 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CEP18665.1 - 4.9e-13 49.0 0.1 1.1e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CEP18665.1 - 6.1e-07 29.6 0.1 1.4e-06 28.5 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CEP18665.1 - 2.5e-06 26.5 0.1 3.3e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CEP18665.1 - 2.8e-05 24.1 0.1 0.001 19.1 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CEP18665.1 - 0.0029 17.7 2.1 0.0073 16.4 0.4 2.3 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 CEP18665.1 - 0.0044 16.5 0.2 0.015 14.8 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Bac_DnaA PF00308.13 CEP18665.1 - 0.012 15.2 2.5 0.18 11.3 1.7 2.3 1 1 0 1 1 1 0 Bacterial dnaA protein Mg_chelatase PF01078.16 CEP18665.1 - 0.039 13.1 0.0 0.28 10.3 0.0 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peptidase_S8 PF00082.17 CEP18666.1 - 2e-62 210.9 1.3 2.9e-62 210.3 0.9 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CEP18666.1 - 1.3e-30 105.0 0.3 3e-30 103.8 0.2 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Mito_carr PF00153.22 CEP18667.1 - 4.3e-26 90.4 5.5 2.7e-17 62.2 0.8 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PSP PF04046.11 CEP18668.1 - 2.7e-11 42.6 0.2 1e-10 40.8 0.1 2.0 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.18 CEP18668.1 - 0.0007 19.4 4.4 0.0007 19.4 3.1 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CEP18668.1 - 0.12 12.0 2.2 0.35 10.5 1.5 1.8 1 0 0 1 1 1 0 Zinc knuckle TFR_dimer PF04253.10 CEP18669.1 - 1.5e-19 69.8 0.1 3.3e-19 68.6 0.0 1.6 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 CEP18669.1 - 1.1e-16 61.0 0.0 2.9e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 CEP18669.1 - 0.00016 21.3 0.0 0.00036 20.1 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CEP18669.1 - 0.00063 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 CEP18669.1 - 0.15 11.2 0.1 0.67 9.1 0.0 2.0 3 0 0 3 3 3 0 Nicastrin Sugar_tr PF00083.19 CEP18672.1 - 4.1e-107 358.5 29.2 9.4e-105 350.7 20.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP18672.1 - 7.1e-26 90.7 27.5 7.1e-26 90.7 19.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP18672.1 - 0.00071 18.0 39.2 0.02 13.3 5.3 3.6 2 2 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 CEP18674.1 - 4e-107 358.5 29.2 9.2e-105 350.8 20.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEP18674.1 - 5.3e-26 91.1 27.1 5.3e-26 91.1 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP18674.1 - 0.00074 18.0 39.3 0.019 13.3 5.3 3.6 2 2 1 3 3 3 2 MFS/sugar transport protein DEAD PF00270.24 CEP18675.1 - 7.9e-40 136.1 0.1 2.2e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DNA_methylase PF00145.12 CEP18675.1 - 1.4e-36 126.3 0.1 3.6e-36 124.9 0.0 1.7 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 CEP18675.1 - 1.5e-28 98.4 1.0 2.6e-28 97.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ima1_N PF09779.4 CEP18675.1 - 1.7e-16 60.9 0.5 1.7e-16 60.9 0.3 1.9 2 0 0 2 2 2 1 Ima1 N-terminal domain AAA_19 PF13245.1 CEP18675.1 - 0.012 15.2 0.1 0.035 13.8 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CEP18675.1 - 0.077 13.1 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPT PF03151.11 CEP18677.1 - 2.4e-13 49.9 6.2 2.4e-13 49.9 4.3 3.1 1 1 2 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 CEP18677.1 - 5.8e-10 38.5 23.7 7.8e-10 38.1 16.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEP18677.1 - 0.00048 20.1 4.4 0.00048 20.1 3.1 3.3 2 2 1 3 3 3 2 EamA-like transporter family SNO PF01174.14 CEP18678.1 - 4.9e-54 182.8 0.1 5.7e-54 182.6 0.1 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 CEP18678.1 - 2.5e-10 40.1 0.0 4.4e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 CEP18678.1 - 1.7e-06 27.6 0.1 3.3e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 CEP18678.1 - 0.00026 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 CEP18678.1 - 0.00038 19.9 0.0 0.0008 18.8 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.8 CEP18678.1 - 0.006 16.0 1.0 3.5 7.0 0.0 3.0 2 1 0 2 2 2 2 Peptidase C26 DUF4066 PF13278.1 CEP18678.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase DIE2_ALG10 PF04922.7 CEP18678.1 - 0.075 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 DIE2/ALG10 family UPF0052 PF01933.13 CEP18679.1 - 1.3e-45 156.0 0.0 2e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PI31_Prot_N PF11566.3 CEP18679.1 - 2.8e-25 88.7 0.0 4.6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 CEP18679.1 - 5.1e-11 43.0 15.3 1.7e-10 41.3 10.6 2.0 1 0 0 1 1 1 1 PI31 proteasome regulator Piwi PF02171.12 CEP18682.1 - 3.1e-102 341.5 0.0 4.9e-102 340.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain E1-E2_ATPase PF00122.15 CEP18682.1 - 2.2e-55 187.1 0.3 4.5e-55 186.1 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP18682.1 - 2.8e-28 98.6 10.0 1.1e-27 96.7 2.4 3.1 3 1 1 4 4 4 2 Cation transporting ATPase, C-terminus PAZ PF02170.17 CEP18682.1 - 1.5e-26 92.2 0.4 3.1e-26 91.2 0.3 1.5 1 0 0 1 1 1 1 PAZ domain Hydrolase PF00702.21 CEP18682.1 - 3.6e-26 92.9 0.0 1.5e-25 90.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1785 PF08699.5 CEP18682.1 - 3.6e-18 64.6 0.0 8e-18 63.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Hydrolase_like2 PF13246.1 CEP18682.1 - 6.8e-18 64.4 0.0 1.4e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP18682.1 - 3.6e-12 46.8 0.0 8.1e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP18682.1 - 1.3e-08 34.2 0.4 8.8e-08 31.5 0.0 2.6 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP18682.1 - 0.00031 20.4 0.2 0.0016 18.0 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Band_7 PF01145.20 CEP18683.1 - 7e-21 74.9 5.2 1.5e-14 54.3 0.4 3.0 2 2 1 3 3 3 2 SPFH domain / Band 7 family Band_7_1 PF13421.1 CEP18683.1 - 0.026 14.0 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF484 PF04340.7 CEP18683.1 - 1.1 8.6 7.2 3.1 7.2 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function, DUF484 Oxidored_FMN PF00724.15 CEP18684.1 - 2.2e-99 332.7 0.0 2.5e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Catalase PF00199.14 CEP18685.1 - 2.4e-196 651.9 1.5 2.9e-196 651.6 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CEP18685.1 - 2.5e-23 81.6 0.0 1.4e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive Met_10 PF02475.11 CEP18686.1 - 8.3e-71 237.7 0.7 1.1e-70 237.2 0.5 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 CEP18686.1 - 0.00019 20.6 0.1 0.00091 18.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 CEP18686.1 - 0.00023 21.2 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CEP18686.1 - 0.0013 19.3 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 CEP18686.1 - 0.003 16.5 0.2 0.0036 16.2 0.1 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 CEP18686.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 CEP18687.1 - 2.2e-08 33.8 12.6 3.7e-08 33.1 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.7 CEP18687.1 - 0.06 11.6 2.4 0.095 11.0 1.6 1.2 1 0 0 1 1 1 0 Per os infectivity Flavodoxin_3 PF12641.2 CEP18687.1 - 0.36 10.2 4.2 0.79 9.1 0.3 2.4 2 0 0 2 2 2 0 Flavodoxin domain Presenilin PF01080.12 CEP18688.1 - 1.6e-84 284.1 8.6 2.1e-84 283.6 6.0 1.2 1 0 0 1 1 1 1 Presenilin Peptidase_A22B PF04258.8 CEP18688.1 - 0.00038 19.9 0.6 0.00038 19.9 0.4 3.2 2 1 1 3 3 3 1 Signal peptide peptidase E1-E2_ATPase PF00122.15 CEP18689.1 - 2.1e-66 223.2 9.7 2.1e-66 223.2 6.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP18689.1 - 1.7e-35 122.1 5.3 1.7e-35 122.1 3.7 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP18689.1 - 3.4e-28 99.5 0.0 3.2e-26 93.0 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP18689.1 - 7e-19 67.5 0.0 1.5e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CEP18689.1 - 2.3e-17 62.1 0.4 7.1e-16 57.4 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEP18689.1 - 6.7e-14 52.4 0.0 1.9e-13 51.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP18689.1 - 7.5e-05 22.4 0.7 0.0049 16.4 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Minor_capsid_1 PF10665.4 CEP18690.1 - 0.041 13.7 0.1 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 Minor capsid protein UPF0147 PF03685.8 CEP18690.1 - 0.045 13.6 1.6 0.11 12.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) PAP_assoc PF03828.14 CEP18692.1 - 5.6e-12 45.4 0.1 1.4e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF2850 PF11012.3 CEP18692.1 - 0.032 14.4 0.6 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) UAA PF08449.6 CEP18693.1 - 5.7e-87 291.4 16.0 6.8e-87 291.2 11.1 1.0 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CEP18693.1 - 0.0016 18.5 4.1 0.0016 18.5 2.8 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CEP18693.1 - 0.0047 16.0 1.8 0.0061 15.6 0.4 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 CEP18693.1 - 0.095 12.3 22.2 0.096 12.3 6.5 2.8 2 2 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.15 CEP18693.1 - 0.39 10.7 29.0 0.1 12.6 6.6 3.3 3 0 0 3 3 3 0 EamA-like transporter family 2OG-FeII_Oxy_2 PF13532.1 CEP18694.1 - 3.8e-06 26.8 0.0 4.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CEP18694.1 - 0.00034 20.8 0.0 0.0004 20.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2917 PF11142.3 CEP18694.1 - 0.023 13.8 0.1 0.044 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) DUF1418 PF07214.7 CEP18695.1 - 0.05 13.2 7.1 10 5.8 4.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1418) Dpy19 PF10034.4 CEP18695.1 - 3 5.8 6.4 4.7 5.2 4.4 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Tetraspannin PF00335.15 CEP18695.1 - 3.9 6.6 10.1 8.2 5.6 6.9 1.6 2 0 0 2 2 2 0 Tetraspanin family Hydrolase_6 PF13344.1 CEP18697.1 - 1.2e-11 44.4 0.0 3.1e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP18697.1 - 1.5e-09 37.3 0.0 4.1e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 CEP18697.1 - 1.3e-05 25.4 0.0 0.021 15.0 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP18697.1 - 0.0013 19.2 0.0 0.71 10.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CEP18697.1 - 0.069 12.5 0.1 0.96 8.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase zf-Tim10_DDP PF02953.10 CEP18698.1 - 2.8e-20 71.3 0.7 3.3e-20 71.1 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CEP18698.1 - 0.003 17.0 0.8 0.016 14.6 0.6 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Xan_ur_permease PF00860.15 CEP18699.1 - 1.2e-25 89.8 30.4 2.4e-24 85.5 19.8 2.7 2 1 0 2 2 2 1 Permease family DUF2834 PF11196.3 CEP18699.1 - 0.028 14.5 5.2 0.1 12.7 1.2 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2834) Herpes_Helicase PF02689.9 CEP18699.1 - 0.037 11.7 0.0 0.055 11.2 0.0 1.1 1 0 0 1 1 1 0 Helicase GxDLY PF14607.1 CEP18700.1 - 0.01 15.3 1.1 0.31 10.4 0.1 2.1 2 0 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type FHA PF00498.21 CEP18701.1 - 3.5e-13 49.4 0.0 8.3e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain G-patch PF01585.18 CEP18701.1 - 1.2e-12 47.4 3.3 9.9e-12 44.4 1.8 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CEP18701.1 - 3.2e-09 36.5 0.0 1e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site PQ-loop PF04193.9 CEP18702.1 - 1.6e-17 62.7 10.1 1.1e-12 47.2 2.8 2.8 2 1 0 2 2 2 2 PQ loop repeat Peptidase_U4 PF03419.8 CEP18702.1 - 0.025 13.6 9.5 0.18 10.8 6.6 1.9 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF1352 PF07086.7 CEP18702.1 - 0.12 11.9 2.6 4.3 6.9 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1352) DUF4044 PF13253.1 CEP18702.1 - 0.34 10.0 4.8 0.9 8.7 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) FA_desaturase PF00487.19 CEP18702.1 - 8.7 5.7 9.2 2.8 7.2 3.4 1.9 2 0 0 2 2 2 0 Fatty acid desaturase Ribosomal_S8e PF01201.17 CEP18703.1 - 2.3e-50 170.1 1.0 2.7e-50 169.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Abhydro_lipase PF04083.11 CEP18704.1 - 5.3e-18 64.1 0.6 1.3e-17 62.8 0.4 1.7 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 CEP18704.1 - 5.8e-13 48.9 0.1 9.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEP18704.1 - 9.5e-08 32.1 0.0 2.5e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP18704.1 - 1.9e-06 27.6 0.0 8.4e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CEP18704.1 - 0.12 11.8 0.4 19 4.6 0.0 2.7 3 1 0 3 3 3 0 Serine hydrolase (FSH1) Bap31 PF05529.7 CEP18705.1 - 2.2e-44 151.2 5.7 2.8e-44 150.8 3.9 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF2987 PF11205.3 CEP18705.1 - 0.15 11.7 4.7 0.25 10.9 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) UBA PF00627.26 CEP18706.1 - 0.033 14.0 0.6 0.048 13.5 0.1 1.5 2 0 0 2 2 2 0 UBA/TS-N domain Borrelia_lipo_1 PF05714.6 CEP18706.1 - 0.058 12.4 0.4 0.072 12.1 0.3 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein Remorin_C PF03763.8 CEP18706.1 - 0.45 10.0 3.2 0.29 10.6 0.6 1.7 1 1 0 1 1 1 0 Remorin, C-terminal region Longin PF13774.1 CEP18707.1 - 2e-31 107.3 0.1 3e-31 106.8 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CEP18707.1 - 5.8e-15 54.6 0.0 8.3e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Matrilin_ccoil PF10393.4 CEP18707.1 - 0.032 13.5 0.1 0.096 12.0 0.1 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin MCD PF05292.6 CEP18708.1 - 4e-77 259.3 0.0 5.7e-52 176.5 0.0 2.1 2 0 0 2 2 2 2 Malonyl-CoA decarboxylase (MCD) HTH_30 PF13556.1 CEP18709.1 - 0.041 13.4 0.1 0.098 12.2 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain RabGAP-TBC PF00566.13 CEP18710.1 - 2.4e-39 135.0 0.3 2.4e-39 135.0 0.2 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain YcfA PF07927.7 CEP18710.1 - 0.052 13.4 0.2 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 YcfA-like protein MBF1 PF08523.5 CEP18711.1 - 4.7e-20 71.3 1.9 8.1e-20 70.6 1.3 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CEP18711.1 - 8.6e-10 38.3 0.4 1.7e-09 37.3 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 CEP18711.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Excalibur PF05901.6 CEP18711.1 - 0.1 12.9 0.0 0.8 10.0 0.0 2.2 1 1 0 1 1 1 0 Excalibur calcium-binding domain DUF1397 PF07165.6 CEP18712.1 - 0.018 14.2 0.6 0.022 13.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) PLA2_B PF01735.13 CEP18713.1 - 2.2e-29 102.0 2.2 6.8e-19 67.3 0.3 3.5 3 1 1 4 4 4 3 Lysophospholipase catalytic domain Colicin_V PF02674.11 CEP18713.1 - 0.16 11.8 0.8 0.27 11.0 0.1 1.7 2 0 0 2 2 2 0 Colicin V production protein Rod-binding PF10135.4 CEP18714.1 - 0.15 12.0 0.1 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Rod binding protein LRR_8 PF13855.1 CEP18715.1 - 0.29 10.9 1.9 4.4 7.1 0.1 3.4 2 1 3 5 5 5 0 Leucine rich repeat DUF2457 PF10446.4 CEP18715.1 - 4 6.0 13.0 5.9 5.4 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Coa1 PF08695.5 CEP18717.1 - 3e-26 91.2 0.3 3.9e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Abhydrolase_2 PF02230.11 CEP18719.1 - 5.5e-57 192.6 0.0 6.5e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CEP18719.1 - 3.1e-10 39.9 0.0 7.6e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEP18719.1 - 1.3e-09 38.3 0.0 0.00013 21.9 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 CEP18719.1 - 6.5e-06 25.7 0.0 1.2e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 CEP18719.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 CEP18719.1 - 0.00019 20.7 0.0 0.00055 19.2 0.0 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CEP18719.1 - 0.0053 16.3 0.1 0.86 9.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.9 CEP18719.1 - 0.011 14.9 0.0 0.028 13.6 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_4 PF08386.5 CEP18719.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein MFS_1 PF07690.11 CEP18720.1 - 4.6e-39 134.1 64.7 1.4e-33 116.1 27.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP18720.1 - 2.3e-10 39.4 20.5 2.3e-10 39.4 14.2 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 CEP18720.1 - 1.2e-06 27.3 34.2 2.3e-05 23.1 6.3 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter Elong_Iki1 PF10483.4 CEP18721.1 - 4.8e-27 95.0 0.1 8e-27 94.3 0.1 1.3 1 1 0 1 1 1 1 Elongator subunit Iki1 GSHPx PF00255.14 CEP18722.1 - 1.2e-10 40.7 0.0 1.7e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 CEP18722.1 - 0.01 15.8 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) DUF962 PF06127.6 CEP18723.1 - 7.9e-22 76.9 3.5 2e-21 75.6 2.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Abhydrolase_5 PF12695.2 CEP18723.1 - 1.5e-08 34.5 0.0 3.9e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP18723.1 - 4.1e-08 32.7 0.1 2.3e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CEP18723.1 - 0.00071 19.5 0.0 0.024 14.5 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 CEP18723.1 - 0.0038 16.6 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 CEP18723.1 - 0.0046 16.2 0.0 0.02 14.2 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.4 CEP18723.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Helicase_IV_N PF12462.3 CEP18723.1 - 0.11 12.1 0.1 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal RICTOR_M PF14666.1 CEP18724.1 - 1.6e-86 289.0 1.7 5.9e-83 277.3 0.4 3.5 2 1 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 CEP18724.1 - 3.3e-77 259.6 7.9 6.3e-77 258.6 1.5 3.5 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 CEP18724.1 - 2.1e-39 134.0 0.1 4.7e-37 126.4 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CEP18724.1 - 6.2e-27 93.3 5.1 3.3e-15 55.7 0.0 6.0 7 0 0 7 7 7 2 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 CEP18724.1 - 1.1e-06 28.3 5.9 1.1e-06 28.3 4.1 2.0 2 0 0 2 2 2 1 Hr1 repeat HEAT_2 PF13646.1 CEP18724.1 - 3e-05 24.2 6.3 0.34 11.2 0.1 5.5 6 0 0 6 6 6 2 HEAT repeats Arm PF00514.18 CEP18724.1 - 0.0056 16.4 11.4 5.8 6.9 0.0 6.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cys_Met_Meta_PP PF01053.15 CEP18725.1 - 4.8e-134 446.4 0.0 5.4e-134 446.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CEP18725.1 - 9.4e-07 27.8 0.0 1.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CEP18725.1 - 2.8e-05 23.2 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 CEP18725.1 - 0.0004 18.7 0.0 0.0029 15.9 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.8 CEP18725.1 - 0.019 13.7 0.0 0.095 11.4 0.0 1.8 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.16 CEP18725.1 - 0.025 13.7 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Galactosyl_T PF01762.16 CEP18726.1 - 2.4e-21 76.2 0.0 3.7e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.3 CEP18726.1 - 1.9e-09 37.3 6.9 4e-09 36.2 4.8 1.6 1 0 0 1 1 1 1 N-glycosylation protein Gly_transf_sug PF04488.10 CEP18726.1 - 2.5e-09 37.4 0.1 7.2e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.7 CEP18726.1 - 0.00023 20.8 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Caps_synth PF05704.7 CEP18726.1 - 0.0015 17.7 0.4 0.0029 16.8 0.3 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Glyco_transf_21 PF13506.1 CEP18726.1 - 0.031 13.5 0.1 0.073 12.3 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF4173 PF13777.1 CEP18726.1 - 0.16 11.2 9.6 0.013 14.7 2.7 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4173) GDI PF00996.13 CEP18727.1 - 1.7e-151 504.5 0.3 1.3e-135 452.0 0.0 2.0 1 1 1 2 2 2 2 GDP dissociation inhibitor DUF3526 PF12040.3 CEP18727.1 - 0.12 12.4 0.1 1.3 9.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3526) Usp PF00582.21 CEP18728.1 - 3.8e-20 72.5 0.0 9.1e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 Universal stress protein family Metallophos PF00149.23 CEP18730.1 - 1.4e-10 40.9 1.7 1.7e-10 40.6 1.2 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 CEP18730.1 - 0.00065 17.8 0.0 0.0016 16.6 0.0 1.5 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase Not1 PF04054.10 CEP18731.1 - 2.7e-110 368.8 0.0 7.9e-110 367.2 0.0 1.9 2 1 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CEP18731.1 - 1.5e-35 122.0 2.2 4.8e-35 120.3 1.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) APC_CDC26 PF10471.4 CEP18731.1 - 0.69 10.6 10.9 6.2 7.6 1.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 FKBP_C PF00254.23 CEP18732.1 - 1.9e-32 111.1 0.0 2.1e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AA_permease_2 PF13520.1 CEP18733.1 - 7e-43 146.7 42.4 9.1e-43 146.3 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease Cyclin_N PF00134.18 CEP18734.1 - 3e-11 42.9 0.0 3.6e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain EutH PF04346.7 CEP18734.1 - 0.0083 15.1 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH Nop PF01798.13 CEP18734.1 - 0.09 12.0 0.2 0.14 11.4 0.2 1.4 1 1 0 1 1 1 0 Putative snoRNA binding domain DUF912 PF06024.7 CEP18735.1 - 0.57 10.2 5.1 4.2 7.4 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) bZIP_2 PF07716.10 CEP18736.1 - 4.9e-13 48.6 16.1 4.9e-13 48.6 11.1 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP18736.1 - 6.8e-13 48.3 11.6 6.8e-13 48.3 8.0 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 CEP18736.1 - 4.7e-07 30.0 8.6 4.7e-07 30.0 6.0 2.6 2 0 0 2 2 2 1 bZIP Maf transcription factor CENP-Q PF13094.1 CEP18736.1 - 4.9e-05 23.4 0.6 4.9e-05 23.4 0.4 2.6 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.10 CEP18736.1 - 0.0029 17.0 4.7 0.0029 17.0 3.3 2.6 2 0 0 2 2 2 1 Septum formation initiator HALZ PF02183.13 CEP18736.1 - 0.026 14.2 6.6 0.13 12.0 2.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 CEP18736.1 - 0.038 14.3 1.7 0.038 14.3 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 CEP18736.1 - 0.27 11.2 5.8 0.066 13.1 1.1 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family IncA PF04156.9 CEP18736.1 - 0.49 9.9 7.6 0.058 12.9 1.7 2.0 2 0 0 2 2 2 0 IncA protein Lge1 PF11488.3 CEP18736.1 - 0.57 10.4 5.8 0.46 10.7 1.9 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 TMCO5 PF14992.1 CEP18736.1 - 2.7 7.0 10.4 0.1 11.7 3.0 1.7 2 0 0 2 2 2 0 TMCO5 family ERM PF00769.14 CEP18736.1 - 7.2 6.0 26.1 0.059 12.8 5.2 3.4 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Nnf1 PF03980.9 CEP18736.1 - 8.3 6.4 14.6 0.11 12.5 2.7 2.9 2 0 0 2 2 2 0 Nnf1 DUF572 PF04502.8 CEP18736.1 - 9.2 5.3 24.7 0.79 8.8 5.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) O-FucT PF10250.4 CEP18737.1 - 2e-07 30.4 0.4 3.3e-07 29.7 0.3 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HLH PF00010.21 CEP18738.1 - 1e-11 44.3 0.4 1.7e-11 43.6 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain F-box-like PF12937.2 CEP18741.1 - 1.1e-12 47.4 1.5 2.8e-12 46.1 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP18741.1 - 1.8e-06 27.4 2.8 5e-06 26.0 1.9 1.8 1 0 0 1 1 1 1 F-box domain Methyltransf_26 PF13659.1 CEP18741.1 - 0.00025 21.0 0.1 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP18741.1 - 0.0077 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP18741.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.11 CEP18741.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.8 CEP18741.1 - 0.036 13.3 0.1 0.13 11.5 0.0 1.9 3 0 0 3 3 3 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 CEP18741.1 - 0.043 14.2 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CEP18741.1 - 0.048 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PRANC PF09372.5 CEP18741.1 - 0.076 12.9 0.3 0.26 11.3 0.2 1.9 1 0 0 1 1 1 0 PRANC domain HMA PF00403.21 CEP18742.1 - 2.6e-53 177.9 5.2 4.5e-14 52.3 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 CEP18742.1 - 8.2e-46 155.8 1.0 8.2e-46 155.8 0.7 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEP18742.1 - 3.1e-42 145.4 0.3 6.5e-42 144.3 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP18742.1 - 1.8e-15 57.6 0.0 7.4e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP18742.1 - 0.00061 19.4 0.4 0.0073 15.9 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_3 PF08777.6 CEP18742.1 - 0.0041 16.9 0.0 4.2 7.2 0.0 2.8 3 0 0 3 3 3 2 RNA binding motif DUF2013 PF09431.5 CEP18744.1 - 4.3e-25 88.1 4.6 1.9e-19 69.7 0.8 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF2013) FTA4 PF13093.1 CEP18744.1 - 0.065 12.6 0.6 0.12 11.7 0.4 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Cyt-b5 PF00173.23 CEP18745.1 - 2.6e-08 33.5 0.4 3.9e-08 32.9 0.3 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 CEP18747.1 - 2.9e-53 180.6 0.0 5.6e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18747.1 - 4e-38 130.9 0.0 6e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP18747.1 - 1.7e-05 23.9 0.0 3.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rab_eff_C PF04698.7 CEP18747.1 - 0.0093 14.1 0.0 0.0093 14.1 0.0 1.7 2 0 0 2 2 2 1 Rab effector MyRIP/melanophilin C-terminus Zip PF02535.17 CEP18747.1 - 4.6 6.1 8.0 7.1 5.5 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UQ_con PF00179.21 CEP18748.1 - 3.4e-40 136.7 0.0 5.4e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEP18748.1 - 0.067 12.9 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Glyco_hydro_46 PF01374.13 CEP18749.1 - 1.3e-25 90.2 0.0 2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Retrotrans_gag PF03732.12 CEP18750.1 - 0.022 14.8 1.6 0.035 14.1 0.5 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein F-actin_cap_A PF01267.12 CEP18751.1 - 7.5e-94 313.7 2.2 8.5e-94 313.5 1.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Vps51 PF08700.6 CEP18751.1 - 0.032 14.0 0.9 0.07 12.9 0.1 1.9 2 0 0 2 2 2 0 Vps51/Vps67 Arrestin_C PF02752.17 CEP18752.1 - 2e-05 24.7 0.5 5.3e-05 23.3 0.4 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Methyltransf_15 PF09445.5 CEP18753.1 - 5.9e-46 156.0 0.0 1.2e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CEP18753.1 - 1.9e-10 40.7 0.0 3.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CEP18753.1 - 6.7e-10 38.8 0.0 1.8e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 CEP18753.1 - 3.9e-07 30.6 0.2 2.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 CEP18753.1 - 1.6e-06 27.8 0.0 3.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 CEP18753.1 - 5.6e-05 23.4 0.4 0.00075 19.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.8 CEP18753.1 - 0.0012 18.0 4.5 0.0039 16.3 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 CEP18753.1 - 0.0066 16.9 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CEP18753.1 - 0.032 13.4 0.0 0.083 12.0 0.0 1.7 1 0 0 1 1 1 0 O-methyltransferase Sec3_C_2 PF15278.1 CEP18753.1 - 1.6 8.9 8.6 0.087 12.9 0.9 2.9 3 0 0 3 3 3 0 Sec3 exocyst complex subunit DUF1212 PF06738.7 CEP18754.1 - 4.7e-36 124.0 10.5 6e-32 110.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CEP18754.1 - 5.2e-14 52.2 12.1 5.2e-14 52.2 8.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) CheC PF04509.7 CEP18754.1 - 0.44 10.3 5.6 0.051 13.3 0.6 1.9 2 0 0 2 2 2 0 CheC-like family Carboxyl_trans PF01039.17 CEP18755.1 - 5.4e-118 394.4 0.0 6.6e-118 394.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Methyltransf_23 PF13489.1 CEP18757.1 - 3.7e-10 39.7 0.0 1.5e-09 37.7 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP18757.1 - 2.5e-09 37.4 0.0 9.3e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP18757.1 - 1.5e-07 31.1 0.0 0.0087 15.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CEP18757.1 - 1e-05 26.0 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP18757.1 - 3.4e-05 24.1 0.0 0.00016 22.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP18757.1 - 0.00048 20.1 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP18757.1 - 0.00052 20.4 0.0 0.0026 18.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP18757.1 - 0.019 14.0 0.0 0.1 11.6 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CEP18757.1 - 0.04 12.9 0.0 0.094 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Rad60-SLD PF11976.3 CEP18759.1 - 0.0014 18.2 0.1 0.0014 18.2 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CEP18759.1 - 0.0036 16.6 0.1 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family EIIA-man PF03610.11 CEP18759.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component RVP_2 PF08284.6 CEP18761.1 - 0.0038 17.1 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease UPF0560 PF10577.4 CEP18763.1 - 0.014 13.6 0.9 0.013 13.7 0.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PRKCSH-like PF12999.2 CEP18764.1 - 5.2e-56 188.9 12.9 9.8e-56 188.0 4.9 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CEP18764.1 - 7e-32 110.0 2.0 8.2e-32 109.8 0.6 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CEP18764.1 - 2.7e-06 28.0 1.8 2.7e-06 28.0 1.2 3.5 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 CEP18764.1 - 0.006 16.4 13.2 0.014 15.2 1.6 3.2 1 1 1 2 2 2 1 Low-density lipoprotein receptor domain class A FlaC_arch PF05377.6 CEP18764.1 - 0.0078 16.0 0.5 0.71 9.8 0.1 2.8 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 CEP18764.1 - 0.011 15.4 12.5 0.18 11.5 0.4 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 CEP18764.1 - 0.068 12.6 4.0 0.38 10.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 CEP18764.1 - 1 8.9 11.6 1.6 8.3 4.1 2.4 2 0 0 2 2 2 0 IncA protein RRN3 PF05327.6 CEP18764.1 - 1.2 7.1 7.1 1.8 6.5 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cluap1 PF10234.4 CEP18764.1 - 2.2 7.3 12.6 3.6 6.7 5.0 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 RRM_1 PF00076.17 CEP18767.1 - 1.9e-15 56.2 0.0 3.1e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP18767.1 - 7.1e-10 38.7 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP18767.1 - 1.6e-07 31.0 0.0 2.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CEP18767.1 - 9.2e-06 26.0 1.9 9.2e-06 26.0 1.3 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 VacA2 PF03077.9 CEP18767.1 - 0.027 14.0 2.1 1.4 8.5 0.1 3.1 3 0 0 3 3 3 0 Putative vacuolating cytotoxin DUF3703 PF12487.3 CEP18767.1 - 0.081 12.6 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) SH3_1 PF00018.23 CEP18768.1 - 7.1e-11 41.3 0.0 1.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP18768.1 - 5.2e-10 38.7 0.0 8.4e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP18768.1 - 1.3e-07 30.9 0.0 2.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAT1 PF09770.4 CEP18768.1 - 7.4 4.6 37.7 8.6 4.4 26.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 U1snRNP70_N PF12220.3 CEP18769.1 - 0.22 11.8 5.0 0.51 10.7 0.2 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Spore_coat_CotO PF14153.1 CEP18769.1 - 0.84 9.0 9.8 0.57 9.5 2.3 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DUF3628 PF12300.3 CEP18769.1 - 2.2 8.2 9.8 0.6 10.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) DUF605 PF04652.11 CEP18769.1 - 3.2 7.0 16.9 4.2 6.6 11.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF912 PF06024.7 CEP18769.1 - 3.6 7.6 11.5 1.2 9.1 2.7 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Plasmodium_Vir PF05795.6 CEP18769.1 - 7.1 5.7 7.0 4.7 6.3 0.1 2.1 1 1 1 2 2 2 0 Plasmodium vivax Vir protein TFIIA PF03153.8 CEP18769.1 - 7.8 6.2 14.5 9.4 6.0 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EAF PF09816.4 CEP18770.1 - 1.3e-06 28.2 4.5 1.5e-05 24.9 3.1 2.5 1 1 0 1 1 1 1 RNA polymerase II transcription elongation factor Zip PF02535.17 CEP18771.1 - 1.8e-61 207.9 14.2 2.4e-60 204.2 9.9 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Cyclase PF04199.8 CEP18772.1 - 8.9e-13 48.2 0.0 2.3e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Putative cyclase SWIB PF02201.13 CEP18772.1 - 1.6e-12 46.9 0.1 3.3e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 CEP18772.1 - 1.6e-11 43.7 1.1 2.7e-11 43.0 0.2 1.7 2 0 0 2 2 2 1 DEK C terminal domain DNA_pol_B PF00136.16 CEP18773.1 - 8.8e-94 314.8 1.6 9.9e-94 314.7 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CEP18773.1 - 3.6e-21 75.3 2.0 7.2e-10 38.2 0.1 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CEP18773.1 - 2.7e-14 52.9 8.7 6.3e-14 51.7 6.0 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta FYVE PF01363.16 CEP18773.1 - 0.57 10.1 3.9 1.3 8.9 2.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-CCHC PF00098.18 CEP18774.1 - 8.2e-49 161.3 51.5 1.3e-08 34.3 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CEP18774.1 - 3e-13 49.2 42.3 0.00052 19.6 0.4 7.0 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 CEP18774.1 - 1.9e-08 33.6 43.8 0.0018 17.7 0.3 7.2 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CEP18774.1 - 0.00062 19.4 42.8 0.094 12.4 0.3 6.4 1 1 6 7 7 7 5 Zinc knuckle zf-CCHC_6 PF15288.1 CEP18774.1 - 0.14 11.8 38.3 0.41 10.3 0.3 6.4 6 1 1 7 7 7 0 Zinc knuckle zf-RING_3 PF14369.1 CEP18774.1 - 2.2 8.3 30.3 0.82 9.7 1.1 4.7 3 1 2 5 5 5 0 zinc-finger UPF0020 PF01170.13 CEP18775.1 - 5.9e-15 55.3 0.0 1.6e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 CEP18775.1 - 9.6e-09 34.5 0.0 5.1e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 CEP18775.1 - 1.2e-08 34.7 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP18775.1 - 2.2e-07 30.2 0.0 4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CEP18775.1 - 4.3e-07 30.3 0.0 9.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP18775.1 - 8.3e-07 29.0 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP18775.1 - 5e-05 22.7 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CEP18775.1 - 0.00087 19.6 0.0 0.0023 18.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP18775.1 - 0.00098 18.8 0.0 0.013 15.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP18775.1 - 0.0016 18.9 0.0 0.0044 17.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEP18775.1 - 0.0018 17.4 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 CEP18775.1 - 0.014 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_Mtase PF02384.11 CEP18775.1 - 0.062 12.3 0.0 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 N-6 DNA Methylase Cons_hypoth95 PF03602.10 CEP18775.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.13 CEP18775.1 - 0.14 11.5 2.2 8.1 5.8 0.0 2.9 2 1 0 2 2 2 0 DNA methylase Vps26 PF03643.10 CEP18776.1 - 2.6e-100 334.7 5.4 3e-100 334.5 3.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 DUF433 PF04255.9 CEP18776.1 - 0.093 12.1 0.0 0.31 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Pkinase PF00069.20 CEP18777.1 - 1.5e-62 211.1 0.0 2e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18777.1 - 3.3e-33 114.8 0.0 4.8e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP18777.1 - 3.7e-05 22.8 0.0 6.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Trs65 PF12735.2 CEP18778.1 - 1.6e-18 67.0 3.2 5.3e-14 52.2 0.6 3.7 2 1 1 3 3 3 2 TRAPP trafficking subunit Trs65 DUF382 PF04037.8 CEP18779.1 - 2.9e-57 192.0 0.5 2.9e-57 192.0 0.4 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 CEP18779.1 - 2e-21 75.1 5.6 4e-21 74.1 3.9 1.6 1 0 0 1 1 1 1 PSP Mito_carr PF00153.22 CEP18780.1 - 5.5e-32 109.3 2.3 2.2e-22 78.5 0.5 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein WD40 PF00400.27 CEP18781.1 - 3.7e-28 96.3 21.0 5.5e-07 29.2 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 CEP18781.1 - 4.7e-26 91.4 0.0 7.7e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CEP18781.1 - 9.8e-12 44.6 0.0 2e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain tRNA-synt_2 PF00152.15 CEP18782.1 - 3.4e-88 295.6 0.0 4.6e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CEP18782.1 - 2.3e-08 33.5 0.0 0.00027 20.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CEP18782.1 - 5.5e-07 29.3 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CEP18782.1 - 0.018 14.6 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Slp PF03843.8 CEP18782.1 - 0.16 10.9 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family FGase PF05013.7 CEP18783.1 - 6.2e-10 39.3 0.6 0.002 18.0 0.0 3.1 2 1 1 3 3 3 3 N-formylglutamate amidohydrolase DDE_3 PF13358.1 CEP18784.1 - 0.00054 19.7 0.0 0.0018 18.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease RP-C_C PF11800.3 CEP18786.1 - 0.13 11.9 3.8 0.15 11.7 2.7 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Pex14_N PF04695.8 CEP18786.1 - 0.15 12.1 3.3 0.16 12.0 2.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dicty_REP PF05086.7 CEP18786.1 - 0.17 9.5 4.8 0.2 9.3 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-protein PF00469.15 CEP18786.1 - 0.52 9.6 3.1 0.61 9.4 2.2 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF3449 PF11931.3 CEP18786.1 - 1 8.8 4.4 1 8.8 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) FAM60A PF15396.1 CEP18786.1 - 1.2 8.8 4.3 1.4 8.6 3.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RVT_1 PF00078.22 CEP18787.1 - 5.4e-18 65.1 0.0 1.3e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEP18787.1 - 9.8e-06 25.8 0.6 2.7e-05 24.3 0.4 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase ADH_N PF08240.7 CEP18789.1 - 7.1e-20 70.7 4.4 1.1e-19 70.1 3.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP18789.1 - 2.4e-18 65.9 0.0 3.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEP18789.1 - 0.00025 20.2 0.0 0.00039 19.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_8 PF13183.1 CEP18789.1 - 0.0081 16.1 2.4 0.018 15.0 1.7 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain ADH_zinc_N_2 PF13602.1 CEP18789.1 - 0.012 16.4 0.0 0.024 15.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CEP18789.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 CEP18789.1 - 0.037 14.3 0.0 0.098 12.9 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain ThiF PF00899.16 CEP18789.1 - 0.16 11.7 1.7 0.34 10.7 0.9 1.8 1 1 0 1 1 1 0 ThiF family Glyco_hydro_15 PF00723.16 CEP18790.1 - 1.1e-128 429.6 0.0 1.5e-128 429.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 SHNi-TPR PF10516.4 CEP18790.1 - 0.085 12.1 0.1 0.28 10.4 0.0 1.8 1 0 0 1 1 1 0 SHNi-TPR Nol1_Nop2_Fmu PF01189.12 CEP18791.1 - 3.2e-22 79.2 0.0 5.1e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 CEP18791.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase SLX9 PF15341.1 CEP18791.1 - 0.083 13.3 8.6 0.14 12.5 4.9 2.0 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 DUF2492 PF10678.4 CEP18791.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) GATA PF00320.22 CEP18792.1 - 1.2e-31 107.7 19.5 2.6e-16 58.6 3.7 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CEP18792.1 - 1.6e-07 30.4 6.4 0.00036 19.7 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 CEP18792.1 - 4.4e-05 22.8 5.5 0.0064 15.9 0.5 2.6 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-CHY PF05495.7 CEP18792.1 - 0.017 15.2 10.5 0.67 10.1 2.4 2.5 2 0 0 2 2 2 0 CHY zinc finger DUF2296 PF10058.4 CEP18792.1 - 0.059 13.1 8.4 0.4 10.4 1.5 2.7 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 CEP18792.1 - 0.15 11.8 17.7 1.1 9.1 1.5 3.4 1 1 1 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.7 CEP18792.1 - 0.38 10.5 7.1 2.1 8.1 0.1 3.3 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.6 CEP18792.1 - 1.7 8.3 12.9 0.38 10.4 0.7 3.1 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 CEP18792.1 - 6 6.2 12.1 0.82 8.9 1.7 3.1 2 2 0 2 2 2 0 zinc-ribbon domain HSP90 PF00183.13 CEP18792.1 - 6.9 4.9 11.6 4.7 5.4 6.1 1.8 2 0 0 2 2 2 0 Hsp90 protein Zn-ribbon_8 PF09723.5 CEP18792.1 - 8.1 6.4 10.0 7.9 6.5 0.0 3.3 4 0 0 4 4 4 0 Zinc ribbon domain Arm PF00514.18 CEP18793.1 - 3.1e-82 267.8 15.1 6e-13 48.0 0.0 9.3 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEP18793.1 - 1.1e-23 83.3 0.1 1.3e-08 35.0 0.0 6.1 2 1 4 7 7 7 6 HEAT repeats IBB PF01749.15 CEP18793.1 - 1.8e-20 72.8 10.1 4.1e-20 71.7 7.0 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 CEP18793.1 - 1.6e-18 66.6 1.9 7.5e-07 29.4 0.0 6.1 5 1 0 5 5 5 3 HEAT-like repeat HEAT PF02985.17 CEP18793.1 - 3.4e-15 54.6 1.0 0.0042 17.0 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 CEP18793.1 - 1e-05 24.8 0.1 0.044 12.9 0.0 3.7 2 1 2 4 4 4 3 Armadillo-like Proteasom_PSMB PF10508.4 CEP18793.1 - 0.01 14.1 0.0 0.05 11.8 0.1 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 CEP18793.1 - 0.016 15.6 0.2 8.4 7.1 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 CEP18793.1 - 0.017 15.0 0.2 1.9 8.4 0.0 3.6 2 1 3 5 5 5 0 V-ATPase subunit H Fe_dep_repr_C PF02742.10 CEP18793.1 - 0.081 12.6 0.5 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain ATP-synt_C PF00137.16 CEP18794.1 - 2.9e-30 103.9 20.3 3.1e-16 59.0 5.3 2.3 2 0 0 2 2 2 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 CEP18794.1 - 0.38 11.0 1.8 0.89 9.8 0.3 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.19 CEP18794.1 - 1 9.0 8.8 0.098 12.2 0.9 2.8 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Memo PF01875.12 CEP18795.1 - 1.4e-84 283.2 0.2 1.6e-84 283.0 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein FA PF08736.6 CEP18795.1 - 0.46 10.3 2.0 5.8 6.7 0.1 2.6 2 0 0 2 2 2 0 FERM adjacent (FA) WD40 PF00400.27 CEP18796.1 - 4.7e-42 140.4 7.6 1.7e-09 37.2 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CEP18796.1 - 1.6e-08 33.1 3.9 0.15 10.1 0.0 4.9 3 1 1 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 CEP18796.1 - 2.5e-05 24.0 0.4 0.025 14.2 0.1 2.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A MMS1_N PF10433.4 CEP18796.1 - 0.00037 18.7 0.0 0.0065 14.6 0.0 2.7 2 2 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Hira PF07569.6 CEP18796.1 - 0.21 10.7 8.5 1.2 8.2 0.0 4.0 2 1 1 5 5 5 0 TUP1-like enhancer of split RRM_1 PF00076.17 CEP18797.1 - 3.7e-07 29.6 0.0 5.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP18797.1 - 1.8e-06 27.8 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP18797.1 - 0.0037 17.0 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.7 CEP18797.1 - 0.032 14.1 1.6 0.047 13.5 1.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pneumo_att_G PF05539.6 CEP18797.1 - 1.6 8.0 10.0 2.5 7.3 6.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CNH PF00780.17 CEP18798.1 - 1.8e-41 142.4 0.0 2.7e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEP18798.1 - 2.3e-39 135.1 0.7 4.7e-39 134.1 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 CEP18798.1 - 8.1e-11 42.0 0.3 3.2e-10 40.0 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 CEP18798.1 - 6.8e-10 38.5 0.1 1.5e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ret_tiss PF10044.4 CEP18799.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Retinal tissue protein WD40 PF00400.27 CEP18800.1 - 3.1e-43 144.1 17.7 1.9e-05 24.3 0.0 11.7 12 0 0 12 12 12 9 WD domain, G-beta repeat eIF2A PF08662.6 CEP18800.1 - 7e-05 22.6 0.0 0.00063 19.5 0.0 2.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Phage_int_SAM_4 PF13495.1 CEP18802.1 - 0.014 15.7 0.2 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FlxA PF14282.1 CEP18803.1 - 1.7 8.6 5.6 6.1 6.8 2.1 2.5 2 0 0 2 2 2 0 FlxA-like protein ACT PF01842.20 CEP18804.1 - 0.028 13.9 0.2 0.098 12.1 0.0 1.8 2 0 0 2 2 2 0 ACT domain Chromo PF00385.19 CEP18805.1 - 4.7e-10 38.9 0.8 8.2e-10 38.2 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CEP18805.1 - 0.0005 19.7 1.4 0.0032 17.1 0.2 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF1987 PF09345.5 CEP18808.1 - 0.018 14.8 0.5 0.043 13.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) DUF4218 PF13960.1 CEP18808.1 - 0.072 12.5 0.3 0.55 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) BSD PF03909.12 CEP18809.1 - 2.5e-18 65.5 0.9 7.3e-10 38.4 0.0 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CEP18809.1 - 1.7e-16 59.6 0.0 3.5e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF1448 PF07289.6 CEP18809.1 - 0.0034 16.3 0.0 0.0082 15.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1448) WH1 PF00568.18 CEP18810.1 - 7.8e-26 89.9 0.2 1.2e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 CEP18810.1 - 1.8e-09 37.8 0.2 4.8e-09 36.4 0.2 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Gly-zipper_OmpA PF13436.1 CEP18810.1 - 0.03 13.9 2.2 0.068 12.8 1.5 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain WH2 PF02205.15 CEP18810.1 - 0.045 13.3 0.2 0.095 12.3 0.2 1.6 1 0 0 1 1 1 0 WH2 motif DUF1539 PF07560.6 CEP18810.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Shadoo PF14999.1 CEP18810.1 - 0.24 11.2 6.2 0.53 10.1 4.3 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DDE_3 PF13358.1 CEP18811.1 - 2.4e-19 69.5 0.6 3.8e-19 68.8 0.4 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CEP18811.1 - 2.4e-16 59.5 0.7 5.5e-16 58.3 0.5 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP18811.1 - 6e-10 39.2 0.6 1.2e-09 38.3 0.2 1.7 2 0 0 2 2 1 1 Winged helix-turn helix TrmB PF01978.14 CEP18811.1 - 7.4e-05 22.3 0.2 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.1 CEP18811.1 - 0.00012 21.5 0.0 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP18811.1 - 0.00016 22.3 1.7 0.00045 20.9 1.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP18811.1 - 0.00047 20.0 0.2 0.013 15.4 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 CEP18811.1 - 0.0006 19.1 0.1 0.076 12.4 0.0 2.9 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.10 CEP18811.1 - 0.0011 18.7 1.2 0.051 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 CEP18811.1 - 0.0013 18.3 0.4 0.18 11.5 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain KorB PF08535.5 CEP18811.1 - 0.0013 18.8 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 KorB domain LacI PF00356.16 CEP18811.1 - 0.0032 17.0 0.2 0.21 11.2 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.5 CEP18811.1 - 0.025 14.1 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_17 PF12728.2 CEP18811.1 - 0.037 14.2 0.0 15 5.9 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.2 CEP18811.1 - 0.067 13.2 1.1 13 5.9 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain Mor PF08765.6 CEP18811.1 - 0.09 12.5 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_1 PF11427.3 CEP18811.1 - 0.11 12.1 0.1 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Tc3 transposase Sel1 PF08238.7 CEP18812.1 - 3.8e-49 164.0 15.5 9e-08 32.5 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_11 PF13414.1 CEP18812.1 - 3.6e-05 23.3 10.1 0.074 12.7 0.0 5.1 1 1 4 5 5 5 3 TPR repeat DUF4244 PF14029.1 CEP18812.1 - 0.24 10.5 2.3 0.44 9.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Hist_deacetyl PF00850.14 CEP18813.1 - 4.5e-81 272.5 0.1 5.6e-81 272.2 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF2800 PF10926.3 CEP18813.1 - 0.17 10.9 0.0 0.5 9.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) NAD_binding_4 PF07993.7 CEP18814.1 - 8.9e-08 31.3 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CEP18814.1 - 0.00023 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CEP18815.1 - 8.7e-32 109.9 0.0 1.5e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.16 CEP18815.1 - 1.7e-05 24.2 0.0 3.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.14 CEP18815.1 - 0.0091 16.2 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 CEP18815.1 - 0.013 14.2 0.0 0.032 12.9 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Telomere_reg-2 PF10193.4 CEP18816.1 - 1.6e-23 83.1 0.0 4.1e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Aldedh PF00171.17 CEP18818.1 - 4.1e-114 381.4 0.0 5e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3425 PF11905.3 CEP18819.1 - 6.3e-10 39.0 0.7 1.2e-08 34.9 0.5 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.10 CEP18819.1 - 0.0052 16.5 10.2 0.011 15.5 7.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Methyltransf_14 PF08484.6 CEP18819.1 - 0.012 15.2 3.4 0.02 14.4 2.3 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain bZIP_Maf PF03131.12 CEP18819.1 - 0.1 12.9 10.6 0.23 11.7 7.4 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DDRGK PF09756.4 CEP18819.1 - 0.1 11.9 5.6 0.17 11.2 3.9 1.3 1 0 0 1 1 1 0 DDRGK domain bZIP_1 PF00170.16 CEP18819.1 - 0.2 11.6 11.6 0.43 10.5 8.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor Zn_clus PF00172.13 CEP18821.1 - 1.9e-09 37.2 14.8 4.1e-09 36.2 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 CEP18822.1 - 1e-44 152.4 0.4 1.1e-44 152.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_9 PF14604.1 CEP18823.1 - 8.3e-33 111.7 3.1 5.6e-12 45.0 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 CEP18823.1 - 4.3e-31 106.0 1.6 2.1e-12 46.2 0.0 3.6 3 0 0 3 3 3 3 SH3 domain SHD1 PF03983.7 CEP18823.1 - 1.2e-30 104.9 0.0 2.5e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 CEP18823.1 - 1.6e-22 78.7 0.0 3.2e-07 29.7 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SAM_1 PF00536.25 CEP18823.1 - 0.024 14.8 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_6 PF15406.1 CEP18823.1 - 0.13 12.3 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Ras PF00071.17 CEP18824.1 - 6.4e-56 188.2 0.1 7.3e-56 188.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP18824.1 - 3.3e-21 75.9 0.1 5.3e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CEP18824.1 - 4.2e-09 36.1 0.1 1.1e-08 34.8 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CEP18824.1 - 1.5e-08 34.1 0.1 1.7e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEP18824.1 - 2.8e-06 27.2 0.1 4.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CEP18824.1 - 0.0014 17.3 0.1 1.3 7.6 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit AAA_22 PF13401.1 CEP18824.1 - 0.066 13.3 0.6 2.4 8.2 0.4 2.5 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.2 CEP18826.1 - 7e-05 22.4 2.5 9.8e-05 22.0 0.5 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CEP18826.1 - 0.0051 16.3 0.4 1.5 8.5 0.0 3.5 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) F-box PF00646.28 CEP18826.1 - 0.063 12.9 0.0 0.063 12.9 0.0 2.3 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.1 CEP18826.1 - 0.13 11.9 6.2 0.6 9.9 0.1 3.9 3 1 0 4 4 4 0 Leucine rich repeat Katanin_con80 PF13925.1 CEP18827.1 - 0.21 11.3 4.9 0.44 10.2 0.3 2.1 1 1 1 2 2 2 0 con80 domain of Katanin PEMT PF04191.8 CEP18828.1 - 2e-53 178.9 10.5 1.9e-30 105.0 0.5 3.5 3 0 0 3 3 3 3 Phospholipid methyltransferase DUF853 PF05872.7 CEP18828.1 - 0.023 13.0 0.8 3.4 5.9 0.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Arrestin_C PF02752.17 CEP18829.1 - 1.2e-16 61.0 0.0 1.7e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEP18829.1 - 8.6e-15 54.8 0.0 2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CEP18829.1 - 3.9e-05 23.2 0.0 9.7e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like DnaJ PF00226.26 CEP18830.1 - 7.9e-18 63.9 0.9 1.5e-17 63.0 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain EST1 PF10374.4 CEP18830.1 - 0.033 14.1 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 Mis12 PF05859.7 CEP18830.1 - 0.062 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Mis12 protein EF1_GNE PF00736.14 CEP18831.1 - 2.2e-31 107.4 1.9 4.3e-31 106.4 1.3 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CEP18831.1 - 1.1e-11 44.5 6.7 1.1e-11 44.5 4.6 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 CEP18831.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2777 PF10949.3 CEP18831.1 - 0.25 11.0 0.2 0.25 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) E1-E2_ATPase PF00122.15 CEP18832.1 - 1.8e-57 194.0 5.9 3.6e-57 193.0 4.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP18832.1 - 4.6e-42 143.5 9.7 4.6e-42 143.5 6.7 3.5 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP18832.1 - 9.6e-34 117.6 0.0 1.9e-32 113.4 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP18832.1 - 8.6e-23 80.1 0.0 1.7e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP18832.1 - 1.3e-14 54.8 0.0 8.1e-14 52.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP18832.1 - 1.4e-13 50.0 0.0 3.4e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP18832.1 - 3.8e-05 23.3 0.4 3.8e-05 23.3 0.3 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2280 PF10045.4 CEP18832.1 - 0.044 13.6 0.2 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) HLH PF00010.21 CEP18834.1 - 4.1e-13 48.8 1.7 9.6e-13 47.6 1.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L37 PF08561.5 CEP18834.1 - 1.6 8.3 6.5 6.3 6.4 4.5 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 SNARE PF05739.14 CEP18835.1 - 1.9e-14 53.0 2.3 1.9e-14 53.0 1.6 3.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CEP18835.1 - 4.4e-13 49.2 3.4 4.4e-13 49.2 2.4 2.7 3 0 0 3 3 2 1 Syntaxin MCPsignal PF00015.16 CEP18835.1 - 7.9e-05 22.2 12.2 0.0029 17.1 2.6 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3040 PF11239.3 CEP18835.1 - 0.0084 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Syntaxin_2 PF14523.1 CEP18835.1 - 0.011 15.7 11.1 0.013 15.5 4.0 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Rifin_STEVOR PF02009.11 CEP18835.1 - 0.012 15.2 8.8 0.063 12.9 6.0 1.9 1 1 0 1 1 1 0 Rifin/stevor family NPV_P10 PF05531.7 CEP18835.1 - 0.017 15.3 11.5 0.25 11.6 0.6 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein T2SF PF00482.18 CEP18835.1 - 0.02 14.7 4.0 1 9.3 0.9 3.0 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Laminin_II PF06009.7 CEP18835.1 - 0.024 14.4 12.2 1.1 9.0 2.2 3.2 2 1 0 2 2 2 0 Laminin Domain II DUF2077 PF09850.4 CEP18835.1 - 0.024 14.0 2.1 0.38 10.1 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF1510 PF07423.6 CEP18835.1 - 0.033 13.5 0.6 0.033 13.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Chordopox_A33R PF05966.7 CEP18835.1 - 0.11 11.2 1.0 0.21 10.3 0.2 1.8 2 0 0 2 2 2 0 Chordopoxvirus A33R protein OppC_N PF12911.2 CEP18835.1 - 0.14 11.5 2.0 0.26 10.6 1.4 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Spectrin PF00435.16 CEP18835.1 - 0.14 12.4 10.5 0.6 10.4 0.4 3.2 2 1 1 3 3 3 0 Spectrin repeat Snapin_Pallidin PF14712.1 CEP18835.1 - 0.16 12.3 9.2 0.78 10.0 0.6 2.8 2 1 0 2 2 2 0 Snapin/Pallidin GP41 PF00517.12 CEP18835.1 - 0.24 10.9 0.1 0.24 10.9 0.1 3.3 2 1 1 3 3 3 0 Retroviral envelope protein DUF3753 PF12575.3 CEP18835.1 - 0.4 10.5 2.4 0.66 9.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) zf-ZPR1 PF03367.8 CEP18835.1 - 0.53 9.4 4.9 1.2 8.2 0.1 2.9 2 1 1 3 3 3 0 ZPR1 zinc-finger domain FlaC_arch PF05377.6 CEP18835.1 - 0.55 10.1 6.7 3.1 7.7 0.2 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF479 PF04336.7 CEP18835.1 - 0.55 10.3 3.4 3.2 7.9 0.2 3.2 1 1 3 5 5 5 0 Protein of unknown function, DUF479 Syntaxin-6_N PF09177.6 CEP18835.1 - 0.61 10.5 12.5 0.8 10.1 1.2 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 CEP18835.1 - 0.76 8.1 13.5 1.2 7.4 8.3 1.8 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 CEP18835.1 - 0.78 8.8 7.6 0.49 9.5 1.3 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Latarcin PF10279.4 CEP18835.1 - 1.1 9.4 4.9 1.1 9.4 0.4 2.6 2 2 0 2 2 2 0 Latarcin precursor DUF2115 PF09888.4 CEP18835.1 - 1.3 9.0 5.6 0.82 9.7 0.5 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Arc_PepC_II PF06847.6 CEP18835.1 - 2.2 8.7 5.1 0.91 9.9 0.2 2.6 2 2 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II UPF0184 PF03670.8 CEP18835.1 - 2.3 8.4 8.2 4.9 7.4 0.1 4.0 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0184) Synaptobrevin PF00957.16 CEP18835.1 - 2.4 7.8 14.8 0.94 9.1 4.2 3.4 2 2 1 3 3 3 0 Synaptobrevin DUF1664 PF07889.7 CEP18835.1 - 2.7 7.7 11.4 17 5.2 0.4 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.5 CEP18835.1 - 3 7.4 6.8 17 5.0 0.1 3.5 3 1 0 3 3 3 0 DASH complex subunit Duo1 RP-C_C PF11800.3 CEP18835.1 - 3.4 7.3 13.2 2.5 7.7 2.2 2.6 1 1 2 3 3 3 0 Replication protein C C-terminal region Sec20 PF03908.8 CEP18835.1 - 4 7.1 9.4 0.8 9.4 0.3 3.1 2 2 1 3 3 3 0 Sec20 Filament PF00038.16 CEP18835.1 - 4 6.8 18.3 0.75 9.2 3.9 2.6 1 1 0 2 2 2 0 Intermediate filament protein DUF2203 PF09969.4 CEP18835.1 - 5.8 7.1 12.7 6.2 7.0 1.3 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) MxiH PF09392.5 CEP18835.1 - 8.2 7.0 11.0 3.4e+02 1.9 7.6 3.1 1 1 0 1 1 1 0 Type III secretion needle MxiH like Atg14 PF10186.4 CEP18835.1 - 8.7 5.1 13.1 11 4.9 0.3 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 eIF-4B PF06273.6 CEP18835.1 - 9 4.9 8.4 0.41 9.3 0.9 1.9 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B PALP PF00291.20 CEP18836.1 - 5.1e-74 249.2 0.2 6.2e-74 248.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CEP18836.1 - 1.5e-42 143.1 0.0 6.1e-23 80.2 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Peptidase_M7 PF02031.11 CEP18837.1 - 0.0085 15.8 0.3 0.02 14.6 0.2 1.6 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family zf-PARP PF00645.13 CEP18837.1 - 0.03 14.5 0.1 0.082 13.1 0.0 1.7 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DASH_Dad2 PF08654.5 CEP18839.1 - 2.2e-07 30.7 1.4 2.7e-07 30.5 0.6 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 Erythro_esteras PF05139.9 CEP18839.1 - 0.017 14.3 0.4 0.019 14.1 0.3 1.0 1 0 0 1 1 1 0 Erythromycin esterase Frizzled PF01534.12 CEP18839.1 - 0.034 12.9 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Iron_permease PF04120.7 CEP18839.1 - 0.094 12.3 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Low affinity iron permease RRM_1 PF00076.17 CEP18840.1 - 2.6e-52 174.3 0.0 5.9e-18 64.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP18840.1 - 2e-33 114.1 0.0 2.6e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP18840.1 - 2.1e-18 65.9 0.0 8.1e-06 25.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP18840.1 - 7.6e-05 22.5 0.0 0.077 12.8 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.3 CEP18840.1 - 0.0052 16.5 0.0 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 DUF1777 PF08648.7 CEP18840.1 - 0.67 9.6 32.0 1.2 8.7 22.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RNase_H2_suC PF08615.6 CEP18841.1 - 1.8e-18 66.6 0.2 2.2e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HrpB7 PF09486.5 CEP18841.1 - 0.024 14.5 0.6 0.041 13.8 0.4 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF1743 PF08489.6 CEP18841.1 - 0.1 12.3 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) DUF3052 PF11253.3 CEP18841.1 - 0.15 11.6 2.3 0.2 11.2 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) DPBB_1 PF03330.13 CEP18843.1 - 1.8e-13 50.3 0.9 9.7e-13 47.9 0.6 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP18843.1 - 0.00057 19.5 0.2 0.00057 19.5 0.1 1.7 2 0 0 2 2 2 1 Barwin family Med17 PF10156.4 CEP18843.1 - 0.01 14.1 0.1 0.014 13.7 0.1 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex CytochromB561_N PF09786.4 CEP18843.1 - 0.023 13.1 1.0 0.024 13.0 0.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2217 PF10265.4 CEP18843.1 - 0.13 10.9 1.4 0.15 10.7 1.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CEP18843.1 - 0.52 8.5 4.5 0.59 8.3 3.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Chitin_synth_2 PF03142.10 CEP18844.1 - 2.9e-245 814.6 0.1 4.1e-245 814.1 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEP18844.1 - 4.7e-130 434.7 6.6 6.3e-130 434.3 4.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 CEP18844.1 - 1.4e-18 66.4 0.0 5.4e-13 48.5 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CEP18844.1 - 5.1e-17 62.4 0.0 2.6e-14 53.6 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEP18844.1 - 5.5e-16 58.8 2.8 5.5e-16 58.8 1.9 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 CEP18844.1 - 1.8e-12 46.8 1.8 6.5e-12 45.0 0.2 2.7 3 0 0 3 3 3 1 DEK C terminal domain Glycos_transf_2 PF00535.21 CEP18844.1 - 6.7e-05 22.6 0.0 0.0058 16.3 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP18844.1 - 0.00017 20.9 0.0 0.004 16.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 NAAA-beta PF15508.1 CEP18844.1 - 0.22 11.8 1.5 3.1 8.2 0.1 2.9 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fungal_trans PF04082.13 CEP18845.1 - 0.00011 21.2 0.3 0.00019 20.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MSG PF02349.10 CEP18845.1 - 0.093 12.7 7.7 0.23 11.4 5.3 1.6 1 0 0 1 1 1 0 Major surface glycoprotein Zn_clus PF00172.13 CEP18845.1 - 0.58 10.1 11.5 1.2 9.1 8.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 CEP18846.1 - 1.9e-18 65.9 0.4 4.1e-10 39.2 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein Syja_N PF02383.13 CEP18848.1 - 0.088 11.5 3.1 0.46 9.1 0.1 2.0 1 1 1 2 2 2 0 SacI homology domain BRE PF06113.7 CEP18849.1 - 0.00041 19.5 0.1 0.00065 18.8 0.1 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Peptidase_S28 PF05577.7 CEP18850.1 - 1.8e-61 208.0 8.4 4.7e-61 206.6 5.8 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CEP18850.1 - 0.0028 17.5 0.0 0.0055 16.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP18850.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 CEP18851.1 - 3.1e-25 89.0 0.0 4.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP18851.1 - 4e-10 39.8 0.0 5.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP18851.1 - 2.2e-08 33.9 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEP18851.1 - 0.00044 20.3 0.1 0.00087 19.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CEP18851.1 - 0.0014 17.5 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 CEP18851.1 - 0.066 12.6 0.1 0.097 12.0 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 CEP18852.1 - 1.2e-58 198.2 0.0 3.6e-58 196.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18852.1 - 5.3e-30 104.3 0.0 1.1e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CEP18852.1 - 6.5e-07 29.7 3.6 1.9e-06 28.3 2.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEP18852.1 - 0.00013 21.0 0.0 0.0022 17.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PBP1_TM PF14812.1 CEP18852.1 - 0.9 9.8 7.9 6.1 7.2 1.3 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3484 PF11983.3 CEP18852.1 - 7.7 7.4 12.0 0.84 10.5 2.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3484) F-box-like PF12937.2 CEP18853.1 - 1.7e-10 40.4 0.2 3.8e-10 39.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP18853.1 - 0.00019 20.9 0.1 0.00043 19.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain AAA_2 PF07724.9 CEP18854.1 - 5.5e-41 140.3 0.1 1.3e-40 139.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.2 CEP18854.1 - 1.2e-23 83.1 0.0 7.6e-15 55.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEP18854.1 - 4e-17 61.0 0.0 1.4e-07 30.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 CEP18854.1 - 6.9e-14 50.5 0.0 6.2e-06 25.9 0.0 3.5 3 0 0 3 3 2 2 Ankyrin repeat Ank_4 PF13637.1 CEP18854.1 - 7.8e-14 51.7 0.1 3.7e-05 24.0 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP18854.1 - 1.1e-12 47.7 0.2 6.4e-05 23.0 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (many copies) ClpB_D2-small PF10431.4 CEP18854.1 - 4.3e-10 39.3 0.0 2.9e-09 36.6 0.0 2.5 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CEP18854.1 - 6.1e-10 38.9 0.0 3.8e-09 36.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CEP18854.1 - 1.7e-08 34.7 0.0 4.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CEP18854.1 - 2.5e-08 33.2 0.0 6.3e-07 28.6 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin Sigma54_activat PF00158.21 CEP18854.1 - 9.7e-07 28.4 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 CEP18854.1 - 1.2e-05 25.5 1.9 0.0037 17.5 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CEP18854.1 - 1.5e-05 25.7 2.2 3.2e-05 24.7 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CEP18854.1 - 2.8e-05 24.2 0.1 0.00023 21.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CEP18854.1 - 0.00034 20.2 0.0 0.0026 17.3 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 CEP18854.1 - 0.00039 20.3 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_33 PF13671.1 CEP18854.1 - 0.00061 19.6 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP18854.1 - 0.00075 19.5 0.8 0.0031 17.5 0.2 2.6 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 CEP18854.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 CEP18854.1 - 0.0082 16.4 0.0 0.039 14.2 0.0 2.2 1 1 0 1 1 1 1 ABC transporter Phage_P2_GpE PF06528.7 CEP18854.1 - 0.012 15.0 0.4 0.026 13.9 0.3 1.5 1 0 0 1 1 1 0 Phage P2 GpE RNA_helicase PF00910.17 CEP18854.1 - 0.021 15.0 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 CEP18854.1 - 0.043 12.9 0.0 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KTI12 PF08433.5 CEP18854.1 - 0.061 12.5 0.0 0.18 10.9 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF815 PF05673.8 CEP18854.1 - 0.083 11.8 0.3 2 7.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NACHT PF05729.7 CEP18854.1 - 0.094 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Rad51 PF08423.6 CEP18855.1 - 3.1e-136 452.2 0.2 3.9e-136 451.9 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 CEP18855.1 - 7e-12 45.0 0.2 1.1e-11 44.4 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 CEP18855.1 - 8.8e-12 44.8 0.0 1.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 CEP18855.1 - 8.3e-11 41.8 1.3 2.5e-10 40.3 0.5 2.1 2 1 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 CEP18855.1 - 2.6e-05 23.4 1.4 5.4e-05 22.4 0.5 1.9 2 1 0 2 2 2 1 KaiC PAXNEB PF05625.6 CEP18855.1 - 0.0026 16.6 0.1 0.023 13.5 0.1 2.0 2 0 0 2 2 2 1 PAXNEB protein AAA_22 PF13401.1 CEP18855.1 - 0.0043 17.1 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain HhH-GPD PF00730.20 CEP18855.1 - 0.0069 16.6 0.1 0.02 15.1 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein AAA PF00004.24 CEP18855.1 - 0.017 15.3 0.1 0.08 13.1 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HHH PF00633.18 CEP18855.1 - 0.029 14.0 0.1 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DnaB_C PF03796.10 CEP18855.1 - 0.073 11.9 0.3 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HTH_28 PF13518.1 CEP18856.1 - 7e-06 25.9 0.6 4.9e-05 23.2 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP18856.1 - 1.9e-05 24.1 0.0 6.3e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CEP18856.1 - 2e-05 24.7 0.0 4.3e-05 23.6 0.0 1.7 2 0 0 2 2 1 1 Winged helix-turn helix HTH_psq PF05225.11 CEP18856.1 - 0.00021 20.7 0.1 0.00073 19.0 0.0 1.9 1 1 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 CEP18856.1 - 0.00032 20.4 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_30 PF13556.1 CEP18856.1 - 0.00065 19.2 0.1 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.22 CEP18856.1 - 0.0013 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR PF01047.17 CEP18856.1 - 0.0032 17.1 0.0 0.0093 15.6 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_38 PF13936.1 CEP18856.1 - 0.0036 16.8 0.2 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 CEP18856.1 - 0.0049 16.2 0.4 0.19 11.1 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 CEP18856.1 - 0.0081 16.3 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 CEP18856.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 MarR family CENP-B_N PF04218.8 CEP18856.1 - 0.011 15.0 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NUMOD1 PF07453.8 CEP18856.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 NUMOD1 domain HTH_3 PF01381.17 CEP18856.1 - 0.014 15.1 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix HTH_8 PF02954.14 CEP18856.1 - 0.018 14.5 0.1 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_5 PF01022.15 CEP18856.1 - 0.02 14.5 0.0 0.066 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MerR_1 PF13411.1 CEP18856.1 - 0.029 14.1 1.1 0.19 11.4 0.7 2.4 1 1 1 2 2 2 0 MerR HTH family regulatory protein HTH_20 PF12840.2 CEP18856.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SpoIIID PF12116.3 CEP18856.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D SH3_8 PF13457.1 CEP18856.1 - 0.085 13.0 0.1 0.21 11.7 0.1 1.7 1 1 0 1 1 1 0 SH3-like domain HTH_Mga PF08280.6 CEP18856.1 - 0.1 12.3 0.2 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Pkinase PF00069.20 CEP18857.1 - 1.7e-59 201.1 0.0 3.7e-59 199.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18857.1 - 6e-23 81.2 0.0 2.3e-22 79.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CEP18857.1 - 0.0086 15.8 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CEP18858.1 - 9.5e-65 218.3 0.0 1.3e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18858.1 - 7.3e-33 113.7 0.0 1.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CEP18858.1 - 2.8e-06 27.3 0.0 6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 CEP18858.1 - 0.00016 20.7 0.0 0.00033 19.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP18858.1 - 0.00094 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3512 PF12024.3 CEP18859.1 - 0.016 14.5 0.1 0.044 13.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) SRR1 PF07985.7 CEP18860.1 - 2.3e-17 62.6 0.0 4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 SRR1 Proteasome PF00227.21 CEP18861.1 - 5.6e-52 175.8 0.1 7.4e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CEP18861.1 - 1.4e-14 53.0 0.1 4.9e-14 51.2 0.0 2.0 1 0 0 1 1 1 1 Proteasome beta subunits C terminal RNase_H PF00075.19 CEP18862.1 - 1.5e-32 112.6 0.1 2.2e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 CEP18862.1 - 5.9e-19 67.8 3.1 6.8e-19 67.6 1.1 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin OGG_N PF07934.7 CEP18863.1 - 6.3e-27 93.8 0.5 2.1e-26 92.2 0.1 2.0 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CEP18863.1 - 5.7e-14 52.3 0.0 9.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CEP18863.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Septin PF00735.13 CEP18865.1 - 1.3e-121 404.9 0.5 1.3e-121 404.9 0.4 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CEP18865.1 - 1.7e-08 34.3 0.0 3.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP18865.1 - 2.1e-07 30.3 0.0 4.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CEP18865.1 - 3.5e-06 26.5 0.3 7.8e-05 22.1 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CEP18865.1 - 0.00011 21.3 0.0 0.00026 20.1 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 CEP18865.1 - 0.00054 19.3 0.0 0.0018 17.7 0.0 1.9 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.18 CEP18865.1 - 0.00089 19.1 3.9 0.25 11.1 0.1 3.1 2 2 1 3 3 3 2 Dynamin family Miro PF08477.8 CEP18865.1 - 0.0024 18.3 0.5 0.011 16.2 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein Gtr1_RagA PF04670.7 CEP18865.1 - 0.0027 16.8 0.0 0.0067 15.5 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CEP18865.1 - 0.0028 17.7 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEP18865.1 - 0.0029 17.1 0.0 0.0064 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 CEP18865.1 - 0.0048 17.1 3.7 0.016 15.4 0.1 2.6 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 CEP18865.1 - 0.0051 16.8 0.2 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CEP18865.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 CEP18865.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CEP18865.1 - 0.04 13.4 0.5 2.3 7.6 0.1 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IpaD PF06511.6 CEP18865.1 - 0.18 10.7 0.1 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 Invasion plasmid antigen IpaD GrpE PF01025.14 CEP18865.1 - 0.64 9.5 10.2 1.6 8.2 6.9 2.0 1 1 0 1 1 1 0 GrpE Exonuc_VII_L PF02601.10 CEP18865.1 - 0.75 8.9 6.4 0.45 9.6 3.2 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF87 PF01935.12 CEP18865.1 - 2.2 8.0 6.2 2.9 7.6 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_12 PF13087.1 CEP18867.1 - 3.4e-34 117.9 0.1 2.2e-20 72.8 0.2 2.6 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.1 CEP18867.1 - 2.3e-32 112.4 0.1 1.5e-31 109.8 0.0 2.5 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 CEP18867.1 - 8.3e-12 45.1 0.2 0.0001 21.9 0.0 3.9 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CEP18867.1 - 3.7e-05 23.7 0.0 9.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CEP18867.1 - 6.3e-05 22.6 0.0 0.00019 21.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CEP18867.1 - 0.016 14.7 0.0 0.2 11.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 CEP18867.1 - 0.028 14.2 0.0 0.1 12.4 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PAT1 PF09770.4 CEP18867.1 - 1.9 6.6 23.0 2.7 6.1 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF262 PF03235.9 CEP18868.1 - 1.5e-16 61.0 3.2 1e-15 58.2 1.9 2.2 1 1 0 1 1 1 1 Protein of unknown function DUF262 ParBc PF02195.13 CEP18868.1 - 0.016 15.2 0.1 0.054 13.6 0.0 1.9 2 0 0 2 2 2 0 ParB-like nuclease domain EzrA PF06160.7 CEP18869.1 - 0.02 13.1 1.9 0.027 12.6 1.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Siah-Interact_N PF09032.6 CEP18869.1 - 0.023 14.7 0.5 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal SlyX PF04102.7 CEP18869.1 - 0.032 14.5 0.5 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 SlyX Streptin-Immun PF11083.3 CEP18869.1 - 0.041 13.8 0.5 0.22 11.5 0.1 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4439 PF14530.1 CEP18869.1 - 0.043 14.2 2.5 0.51 10.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4439) P4Ha_N PF08336.6 CEP18869.1 - 0.053 13.3 0.6 0.1 12.4 0.1 1.6 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DASH_Dad3 PF08656.5 CEP18869.1 - 0.063 12.9 0.3 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 Val_tRNA-synt_C PF10458.4 CEP18869.1 - 0.084 12.9 0.8 8.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DASH_Spc34 PF08657.5 CEP18869.1 - 0.12 11.9 3.1 0.22 11.1 2.1 1.4 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF342 PF03961.8 CEP18869.1 - 0.15 10.4 0.9 0.19 10.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SOBP PF15279.1 CEP18869.1 - 0.17 12.2 11.1 0.25 11.6 7.7 1.3 1 1 0 1 1 1 0 Sine oculis-binding protein DUF1192 PF06698.6 CEP18869.1 - 0.18 11.6 4.5 0.88 9.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MerR-DNA-bind PF09278.6 CEP18869.1 - 0.22 11.9 1.8 0.5 10.7 0.6 2.1 2 0 0 2 2 2 0 MerR, DNA binding Syntaxin-6_N PF09177.6 CEP18869.1 - 0.26 11.7 2.2 0.92 9.9 0.1 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal PspA_IM30 PF04012.7 CEP18869.1 - 0.33 10.2 6.0 0.77 9.0 3.9 1.7 1 1 0 1 1 1 0 PspA/IM30 family Med9 PF07544.8 CEP18869.1 - 0.48 10.1 4.2 0.43 10.3 0.3 2.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Lzipper-MIP1 PF14389.1 CEP18869.1 - 0.49 10.5 3.0 3.8 7.6 2.1 2.4 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 CEP18869.1 - 0.67 9.4 3.3 0.82 9.2 0.6 2.0 2 0 0 2 2 2 0 Septum formation initiator AIP3 PF03915.8 CEP18869.1 - 0.73 8.6 4.3 2.1 7.1 3.0 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 Prefoldin PF02996.12 CEP18869.1 - 0.76 9.4 3.6 10 5.7 0.5 2.4 2 0 0 2 2 2 0 Prefoldin subunit DivIVA PF05103.8 CEP18869.1 - 1 9.4 9.0 0.34 10.9 0.5 2.2 2 0 0 2 2 2 0 DivIVA protein Bap31 PF05529.7 CEP18869.1 - 1.4 8.3 4.2 1.2 8.6 0.1 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF3373 PF11853.3 CEP18869.1 - 4.5 5.6 5.3 61 1.9 3.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Mito_carr PF00153.22 CEP18870.1 - 2.8e-29 100.6 3.1 2e-16 59.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein OrfB_Zn_ribbon PF07282.6 CEP18871.1 - 6.9e-09 35.2 3.1 6.9e-09 35.2 2.2 2.2 3 0 0 3 3 3 1 Putative transposase DNA-binding domain zf-DNL PF05180.7 CEP18871.1 - 0.032 13.9 2.3 0.08 12.6 1.6 1.7 1 0 0 1 1 1 0 DNL zinc finger YfhO PF09586.5 CEP18871.1 - 0.68 7.8 5.4 0.88 7.5 3.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DDE_3 PF13358.1 CEP18874.1 - 4.4e-10 39.4 0.0 6.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Na_sulph_symp PF00939.14 CEP18875.1 - 3.4e-72 243.8 29.9 4.6e-49 167.5 3.8 3.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region Kelch_4 PF13418.1 CEP18876.1 - 3.4e-21 74.7 8.0 2.9e-07 30.1 0.2 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP18876.1 - 1.4e-10 40.8 7.6 0.00059 19.9 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.1 CEP18876.1 - 2.7e-10 40.1 6.5 0.00035 20.6 0.0 4.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP18876.1 - 1.1e-08 34.8 2.2 0.3 11.1 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CEP18876.1 - 6.9e-06 25.6 1.1 0.0005 19.7 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 CEP18876.1 - 0.00013 21.4 3.3 1.4 8.5 0.1 4.4 4 0 0 4 4 4 2 Kelch motif BNR PF02012.15 CEP18877.1 - 0.00011 21.5 68.9 3.5 7.8 0.0 15.4 15 0 0 15 15 15 10 BNR/Asp-box repeat DUF936 PF06075.7 CEP18878.1 - 0.59 8.9 27.8 0.61 8.9 19.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF2992 PF11208.3 CEP18878.1 - 0.77 9.6 27.4 1.2 9.0 19.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) GAGA_bind PF06217.7 CEP18878.1 - 0.96 9.3 21.8 1.4 8.8 15.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family TATR PF03430.8 CEP18878.1 - 1.5 7.3 21.6 1.8 7.1 15.0 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF1510 PF07423.6 CEP18878.1 - 1.8 7.8 24.5 2.5 7.4 17.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1682 PF07946.9 CEP18878.1 - 2.6 6.7 19.7 3.4 6.4 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.7 CEP18878.1 - 2.7 7.8 21.9 3.4 7.4 15.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.10 CEP18878.1 - 3.8 6.1 9.3 4.8 5.7 6.4 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paramyxo_ncap PF00973.14 CEP18878.1 - 7.4 5.1 14.5 8.2 4.9 10.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vfa1 PF08432.5 CEP18878.1 - 8.6 6.3 29.5 12 5.9 20.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 UBX PF00789.15 CEP18879.1 - 5.9e-15 55.0 0.0 1.2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Asp-B-Hydro_N PF05279.6 CEP18879.1 - 0.097 12.5 12.9 0.14 11.9 8.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PX PF00787.19 CEP18880.1 - 0.00041 20.1 4.0 0.00095 18.9 2.7 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 CEP18880.1 - 0.0018 17.8 1.6 0.0065 16.1 0.1 2.6 3 0 0 3 3 3 1 PB1 domain Glyoxalase PF00903.20 CEP18882.1 - 1.1e-24 86.8 0.1 1.4e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CEP18882.1 - 6.1e-16 58.9 0.0 8.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CEP18882.1 - 3.3e-09 36.7 0.0 1.1e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CEP18882.1 - 0.00063 19.7 0.0 0.0085 16.0 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Toxin_67 PF15545.1 CEP18882.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 67 RNase_T PF00929.19 CEP18883.1 - 2.4e-15 57.1 0.8 1.2e-14 54.9 0.1 2.3 2 0 0 2 2 2 1 Exonuclease An_peroxidase PF03098.10 CEP18884.1 - 1.1e-73 248.4 0.0 2.9e-71 240.4 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase Ku_PK_bind PF08785.6 CEP18884.1 - 0.065 13.1 0.9 0.19 11.6 0.6 1.8 1 0 0 1 1 1 0 Ku C terminal domain like zf-RVT PF13966.1 CEP18885.1 - 4e-07 30.2 0.8 9.2e-07 29.1 0.5 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Pkinase PF00069.20 CEP18886.1 - 1.7e-69 233.8 0.0 3.7e-69 232.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18886.1 - 2.7e-49 167.6 0.0 5.1e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CEP18886.1 - 6.9e-07 29.1 0.0 2.1e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 CEP18886.1 - 1.8e-06 27.1 0.0 0.00017 20.6 0.0 2.4 2 0 0 2 2 2 1 Kinase-like SAM_2 PF07647.12 CEP18886.1 - 2.2e-05 24.2 0.3 4.9e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 CEP18886.1 - 0.034 14.6 0.0 0.096 13.1 0.0 1.8 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain APH PF01636.18 CEP18886.1 - 0.13 11.9 3.7 0.36 10.5 0.2 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family FA_hydroxylase PF04116.8 CEP18887.1 - 6.4e-15 55.5 19.7 6.4e-15 55.5 13.7 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily RNase_HII PF01351.13 CEP18888.1 - 1.9e-58 197.3 0.0 3.9e-58 196.3 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease HII Pyr_redox_2 PF07992.9 CEP18890.1 - 4.4e-25 88.7 0.0 5.8e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP18890.1 - 1.6e-09 38.0 0.0 7e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP18890.1 - 0.00013 22.1 0.0 0.084 12.9 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Med29 PF11568.3 CEP18890.1 - 0.037 14.0 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 29 RNA_pol_3_Rpc31 PF11705.3 CEP18891.1 - 4.1e-34 118.5 12.6 5.5e-34 118.1 8.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.5 CEP18891.1 - 0.017 14.2 9.8 0.018 14.1 6.8 1.2 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 CEP18891.1 - 1.9 7.9 11.5 15 4.9 7.2 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CobT PF06213.7 CEP18891.1 - 3.1 6.8 15.0 3.7 6.5 10.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT WD40 PF00400.27 CEP18892.1 - 1e-15 56.9 14.6 0.00055 19.7 0.3 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat bZIP_1 PF00170.16 CEP18894.1 - 3e-10 39.8 13.0 3e-10 39.8 9.0 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CEP18894.1 - 4.5e-10 39.1 12.9 4.5e-10 39.1 9.0 2.5 2 1 0 2 2 2 1 Basic region leucine zipper Planc_extracel PF07595.7 CEP18894.1 - 0.013 15.0 1.1 0.045 13.4 0.8 2.0 1 0 0 1 1 1 0 Planctomycete extracellular HAP1_N PF04849.8 CEP18894.1 - 0.053 12.4 14.0 0.11 11.3 9.7 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region NAM-associated PF14303.1 CEP18894.1 - 0.41 10.9 11.0 0.61 10.3 7.6 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Macoilin PF09726.4 CEP18894.1 - 2.2 6.4 16.1 2.9 6.0 11.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DPBB_1 PF03330.13 CEP18895.1 - 7.8e-15 54.6 0.2 4e-14 52.3 0.0 2.4 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP18895.1 - 4.7e-05 23.0 1.3 4.7e-05 23.0 0.9 2.1 1 1 0 2 2 2 1 Barwin family Pex14_N PF04695.8 CEP18895.1 - 0.00088 19.3 2.1 0.00088 19.3 1.5 1.9 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2413 PF10310.4 CEP18895.1 - 0.0045 15.8 10.4 0.0054 15.6 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) NifU PF01106.12 CEP18895.1 - 0.11 12.3 0.1 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 NifU-like domain BLVR PF06375.6 CEP18895.1 - 0.95 9.2 14.9 2 8.2 10.4 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TraG-D_C PF12696.2 CEP18895.1 - 0.97 9.3 7.8 2.4 8.0 5.4 1.7 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG RVT_1 PF00078.22 CEP18897.1 - 5.3e-31 107.6 0.0 1.1e-30 106.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP18897.1 - 2.6e-11 43.9 0.4 4.1e-11 43.2 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP18897.1 - 1.4e-06 27.8 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 CEP18898.1 - 0.0039 17.0 14.2 0.031 14.2 0.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.1 CEP18898.1 - 0.073 12.7 9.1 1.2 8.8 0.7 2.8 2 0 0 2 2 2 0 Zinc knuckle DUF2387 PF09526.5 CEP18898.1 - 0.45 10.4 4.7 1.4 8.8 3.3 1.9 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) HLH PF00010.21 CEP18899.1 - 1.4e-17 63.1 1.8 1.4e-17 63.1 1.3 2.5 3 1 1 4 4 4 1 Helix-loop-helix DNA-binding domain POP1 PF06978.6 CEP18899.1 - 0.078 12.6 5.4 0.12 11.9 3.8 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Fib_alpha PF08702.5 CEP18899.1 - 0.4 10.8 3.1 0.85 9.7 2.2 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GreA_GreB_N PF03449.10 CEP18899.1 - 2.4 8.2 6.0 1.6 8.8 0.4 2.3 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal NMD3 PF04981.8 CEP18901.1 - 1.9e-79 266.1 1.4 3e-79 265.4 1.0 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 CEP18901.1 - 0.0058 16.4 7.7 0.035 13.9 4.0 2.7 2 1 1 3 3 3 1 Double zinc ribbon zf-NADH-PPase PF09297.6 CEP18901.1 - 0.2 11.2 1.5 0.57 9.7 1.0 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 CEP18901.1 - 0.77 9.0 11.4 25 4.2 7.9 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L24e PF01246.15 CEP18902.1 - 9.6e-30 102.2 4.7 9.6e-30 102.2 3.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2996 PF11210.3 CEP18903.1 - 0.027 14.7 0.1 0.057 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) FlaC_arch PF05377.6 CEP18903.1 - 0.18 11.7 1.8 1.8 8.5 0.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spectrin PF00435.16 CEP18903.1 - 2.4 8.4 12.7 0.44 10.8 3.4 2.5 2 0 0 2 2 2 0 Spectrin repeat Syntaxin-6_N PF09177.6 CEP18903.1 - 4.4 7.7 11.9 1.7 9.0 3.3 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MCPsignal PF00015.16 CEP18903.1 - 4.9 6.6 12.6 8.2 5.9 2.7 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 CEP18903.1 - 5.5 6.8 9.3 0.82 9.4 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MRP-L46 PF11788.3 CEP18904.1 - 2.6e-19 69.9 4.0 4.5e-19 69.1 2.6 1.6 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 CEP18904.1 - 2.2e-06 27.3 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain ATP-synt_B PF00430.13 CEP18904.1 - 0.57 9.9 6.9 0.41 10.4 3.1 1.9 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Glyco_hydro_18 PF00704.23 CEP18905.1 - 1.1e-72 245.3 1.5 1.5e-72 244.9 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-HC5HC2H PF13771.1 CEP18906.1 - 3.9e-16 58.9 13.2 3.9e-16 58.9 9.1 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CEP18906.1 - 1.5e-14 53.9 14.1 4.8e-14 52.2 9.6 2.0 1 1 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 CEP18906.1 - 1.4e-13 50.0 1.2 2.6e-13 49.2 0.9 1.5 1 0 0 1 1 1 1 jmjN domain JmjC PF02373.17 CEP18906.1 - 1.7e-11 44.3 6.5 1.9e-09 37.7 0.2 3.2 3 1 1 4 4 4 2 JmjC domain, hydroxylase YIF1 PF03878.10 CEP18907.1 - 1.3e-69 234.0 2.1 1.8e-69 233.5 1.5 1.1 1 0 0 1 1 1 1 YIF1 BAF1_ABF1 PF04684.8 CEP18907.1 - 9.5 4.9 11.9 13 4.5 8.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GDI PF00996.13 CEP18908.1 - 2.1e-69 233.9 1.9 2.3e-54 184.4 0.3 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor FTA4 PF13093.1 CEP18908.1 - 0.047 13.1 0.3 0.094 12.1 0.2 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 UPF0060 PF02694.10 CEP18908.1 - 0.1 12.6 0.1 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Acyl-CoA_dh_1 PF00441.19 CEP18910.1 - 5.6e-19 68.7 0.4 6.6e-12 45.7 0.1 2.5 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEP18910.1 - 1e-18 66.5 0.3 2e-18 65.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 CEP18910.1 - 1.3e-17 63.3 0.1 2.6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 CEP18910.1 - 2.8e-16 60.0 0.0 8.1e-16 58.6 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF1933 PF09147.5 CEP18910.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) WD40 PF00400.27 CEP18911.1 - 2.7e-53 176.0 11.8 1.3e-09 37.5 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.28 CEP18911.1 - 1.4e-07 30.9 0.5 3.3e-07 29.7 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEP18911.1 - 1.6e-05 24.5 0.2 3.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CEP18911.1 - 0.0025 16.0 0.1 2.9 5.8 0.0 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CEP18911.1 - 0.13 12.5 1.5 35 4.8 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain MS_channel PF00924.13 CEP18911.1 - 0.15 11.3 1.9 0.29 10.4 1.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel EIF_2_alpha PF07541.7 CEP18912.1 - 2.8e-41 139.8 0.2 8e-41 138.3 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CEP18912.1 - 1.8e-13 50.3 1.9 4.3e-13 49.1 1.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 CEP18912.1 - 0.087 12.7 0.1 0.22 11.4 0.1 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Bap31 PF05529.7 CEP18913.1 - 3e-46 157.3 2.0 3.5e-46 157.0 1.4 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF3920 PF13058.1 CEP18913.1 - 0.0084 15.9 1.6 0.014 15.2 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3920) DUF3498 PF12004.3 CEP18913.1 - 0.016 14.3 5.0 0.022 13.9 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DUF2065 PF09838.4 CEP18913.1 - 0.034 13.8 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) TENA_THI-4 PF03070.11 CEP18913.1 - 0.068 12.9 4.3 0.26 11.0 1.6 2.1 1 1 1 2 2 2 0 TENA/THI-4/PQQC family IncA PF04156.9 CEP18913.1 - 0.37 10.3 10.6 0.69 9.4 7.3 1.4 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 CEP18913.1 - 0.41 10.9 6.8 0.53 10.5 4.7 1.2 1 0 0 1 1 1 0 AAA domain DUF4303 PF14136.1 CEP18913.1 - 0.9 9.1 5.7 0.6 9.7 2.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) GrpE PF01025.14 CEP18913.1 - 1.6 8.2 9.3 2.5 7.6 6.5 1.3 1 0 0 1 1 1 0 GrpE WHEP-TRS PF00458.15 CEP18913.1 - 7.2 6.3 7.9 0.28 10.8 0.3 2.4 2 1 1 3 3 3 0 WHEP-TRS domain zf-CSL PF05207.8 CEP18914.1 - 7.5e-26 89.4 1.9 7.5e-26 89.4 1.3 1.4 2 0 0 2 2 2 1 CSL zinc finger Zn-ribbon_8 PF09723.5 CEP18914.1 - 0.0071 16.2 1.2 0.015 15.2 0.8 1.5 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_5 PF13719.1 CEP18914.1 - 0.023 14.2 1.1 0.035 13.6 0.3 1.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF164 PF02591.10 CEP18914.1 - 0.03 14.1 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain zinc_ribbon_4 PF13717.1 CEP18914.1 - 0.1 12.3 1.2 0.14 11.8 0.3 1.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 CEP18914.1 - 0.59 9.7 3.9 1.5 8.5 2.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RCC1 PF00415.13 CEP18915.1 - 3.3e-75 248.1 1.9 1.9e-10 40.8 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEP18915.1 - 1.2e-40 136.3 29.3 4.9e-07 29.1 0.1 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 CEP18915.1 - 0.054 12.9 1.4 5 6.6 0.0 4.3 5 0 0 5 5 5 0 Putative carbohydrate binding domain Kelch_2 PF07646.10 CEP18915.1 - 0.063 13.0 1.2 10 6.0 0.0 4.0 5 0 0 5 5 5 0 Kelch motif Hira PF07569.6 CEP18915.1 - 0.52 9.5 2.4 4.3 6.4 0.1 3.5 5 0 0 5 5 5 0 TUP1-like enhancer of split Gtr1_RagA PF04670.7 CEP18916.1 - 2.2e-73 246.2 0.5 3.2e-73 245.7 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CEP18916.1 - 1.3e-06 27.7 0.7 1.8e-06 27.3 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CEP18916.1 - 7.5e-06 26.4 0.0 2.5e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CEP18916.1 - 3.2e-05 23.3 0.1 0.00012 21.5 0.1 1.8 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 CEP18916.1 - 0.00014 21.1 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEP18916.1 - 0.00024 21.0 0.0 0.0033 17.3 0.0 2.4 1 1 0 2 2 2 1 50S ribosome-binding GTPase WD40 PF00400.27 CEP18917.1 - 4.8e-07 29.4 1.2 0.015 15.1 0.2 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat CPSF_A PF03178.10 CEP18917.1 - 0.0068 15.5 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region Stig1 PF04885.8 CEP18917.1 - 0.082 13.1 0.4 0.082 13.1 0.3 1.6 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 RNA_pol_Rpb2_4 PF04566.8 CEP18917.1 - 0.12 12.2 0.2 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 Ofd1_CTDD PF10637.4 CEP18918.1 - 7.7e-80 267.8 0.0 3.7e-74 249.1 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CEP18918.1 - 9e-13 48.5 0.0 1.7e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_repr_REX1B PF14966.1 CEP18919.1 - 5.4e-19 68.3 3.7 2.3e-18 66.3 0.8 2.0 1 1 1 2 2 2 1 DNA repair REX1-B DUF4303 PF14136.1 CEP18919.1 - 0.0039 16.8 2.0 0.0054 16.3 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4303) Med4 PF10018.4 CEP18919.1 - 0.01 15.2 2.9 0.01 15.2 2.0 2.4 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Cytochrom_B562 PF07361.6 CEP18919.1 - 0.028 14.8 0.4 0.028 14.8 0.3 2.3 1 1 1 2 2 2 0 Cytochrome b562 NAAA-beta PF15508.1 CEP18919.1 - 0.037 14.3 0.2 0.96 9.8 0.0 2.8 1 1 2 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TraC_F_IV PF11130.3 CEP18919.1 - 0.078 12.3 0.1 0.29 10.5 0.0 1.7 1 1 1 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer LRAT PF04970.8 CEP18919.1 - 0.13 12.2 1.8 0.21 11.5 1.3 1.6 1 1 0 1 1 1 0 Lecithin retinol acyltransferase CCDC84 PF14968.1 CEP18919.1 - 0.14 11.6 1.7 0.19 11.2 1.2 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 VirionAssem_T7 PF11653.3 CEP18919.1 - 0.14 12.9 0.9 0.22 12.2 0.7 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein DUF445 PF04286.7 CEP18919.1 - 0.74 9.2 6.3 0.87 9.0 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) COG2 PF06148.6 CEP18919.1 - 0.85 9.4 7.2 0.53 10.1 0.6 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 CEP18919.1 - 1.1 8.2 9.9 1.4 7.8 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TetR_C_5 PF08360.6 CEP18919.1 - 1.3 9.0 7.3 2.2 8.2 0.3 2.5 2 1 1 3 3 3 0 QacR-like protein, C-terminal region DUF1664 PF07889.7 CEP18919.1 - 7.4 6.3 8.3 2.9 7.6 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 CEP18919.1 - 8.5 6.7 10.7 4.5 7.6 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) KID PF02524.9 CEP18919.1 - 8.7 6.9 6.5 12 6.5 0.5 3.5 3 0 0 3 3 3 0 KID repeat Seryl_tRNA_N PF02403.17 CEP18919.1 - 8.8 6.3 12.4 24 5.0 4.7 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-Tim10_DDP PF02953.10 CEP18920.1 - 3.9e-23 80.5 2.8 4.5e-23 80.3 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Peptidase_C32 PF05411.7 CEP18920.1 - 0.16 11.7 0.5 0.2 11.3 0.3 1.2 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase CNH PF00780.17 CEP18921.1 - 7.1e-55 186.3 0.0 1.1e-54 185.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEP18921.1 - 3.4e-34 118.2 1.1 9.6e-34 116.8 0.8 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 CEP18921.1 - 1.6e-20 73.4 0.0 5e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2256 PF10013.4 CEP18922.1 - 0.084 12.6 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Metallophos PF00149.23 CEP18923.1 - 2.1e-13 50.1 0.2 8.1e-13 48.2 0.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEP18923.1 - 1.4e-10 41.2 0.0 3.9e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FAD_binding_3 PF01494.14 CEP18924.1 - 5.5e-20 71.7 0.3 3.6e-19 69.0 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEP18924.1 - 1.3e-08 34.1 0.1 0.0042 16.0 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEP18924.1 - 0.00022 21.1 0.0 0.00057 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEP18924.1 - 0.00067 19.5 0.3 0.046 13.5 0.2 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CEP18924.1 - 0.00086 18.2 0.0 0.0094 14.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.17 CEP18924.1 - 0.0018 17.2 0.1 0.0062 15.4 0.1 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 CEP18924.1 - 0.0026 18.1 0.1 0.044 14.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CEP18924.1 - 0.003 17.2 0.0 0.0067 16.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 CEP18924.1 - 0.0038 15.9 2.5 0.12 10.9 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase HTH_Tnp_Tc3_2 PF01498.13 CEP18926.1 - 7.9e-16 57.8 1.4 2.2e-15 56.4 0.5 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 CEP18926.1 - 1.5e-10 41.2 0.9 2.6e-10 40.4 0.2 1.7 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.14 CEP18926.1 - 1.7e-05 24.4 0.1 0.00071 19.2 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.1 CEP18926.1 - 4.7e-05 22.8 0.1 0.074 12.7 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 CEP18926.1 - 7.1e-05 22.2 1.2 0.001 18.5 0.0 2.9 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_28 PF13518.1 CEP18926.1 - 0.00011 22.0 1.0 0.0052 16.7 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP18926.1 - 0.00011 22.8 1.0 0.00011 22.8 0.7 2.1 2 2 1 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.10 CEP18926.1 - 0.00013 21.7 1.0 0.023 14.5 0.0 3.0 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase LacI PF00356.16 CEP18926.1 - 0.00026 20.5 0.2 0.031 13.9 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_24 PF13412.1 CEP18926.1 - 0.00078 18.7 0.5 0.035 13.4 0.0 2.9 3 1 0 3 3 3 1 Winged helix-turn-helix DNA-binding KorB PF08535.5 CEP18926.1 - 0.00083 19.4 0.1 0.0038 17.3 0.0 2.1 2 1 0 2 2 2 1 KorB domain HTH_IclR PF09339.5 CEP18926.1 - 0.0044 16.5 0.0 3.6 7.2 0.0 2.5 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_17 PF12728.2 CEP18926.1 - 0.0098 16.1 0.0 6.5 7.0 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain Mor PF08765.6 CEP18926.1 - 0.017 14.8 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Mor transcription activator family DUF2774 PF11242.3 CEP18926.1 - 0.062 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 CEP18926.1 - 0.082 12.3 0.1 3.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 Folliculin PF11704.3 CEP18927.1 - 0.035 13.6 1.0 0.048 13.2 0.7 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4301 PF14134.1 CEP18928.1 - 0.012 14.1 0.6 0.015 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Cellulase PF00150.13 CEP18929.1 - 2.1e-14 53.4 0.3 3.7e-14 52.5 0.2 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 CEP18930.1 - 1.2e-56 191.7 0.1 4.4e-56 189.9 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18930.1 - 9.2e-22 77.3 0.3 7.1e-17 61.3 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CEP18930.1 - 0.00059 19.6 0.1 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CEP18930.1 - 0.0066 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 WGR PF05406.10 CEP18930.1 - 0.16 11.9 1.3 0.47 10.4 0.9 1.7 1 0 0 1 1 1 0 WGR domain tRNA_Me_trans PF03054.11 CEP18931.1 - 5.8e-118 393.5 0.0 6.6e-118 393.3 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 CEP18931.1 - 1.5e-05 24.5 0.0 6.1e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 CEP18931.1 - 3.1e-05 23.0 0.0 0.00016 20.6 0.0 1.9 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 CEP18931.1 - 0.00096 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 CEP18931.1 - 0.0027 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family QueC PF06508.8 CEP18931.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Sec1 PF00995.18 CEP18932.1 - 1.8e-126 423.0 0.0 2.3e-126 422.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Rapamycin_bind PF08771.6 CEP18932.1 - 0.068 13.2 1.0 10 6.3 0.1 2.7 2 0 0 2 2 2 0 Rapamycin binding domain Nup54 PF13874.1 CEP18934.1 - 6.1e-33 113.4 9.2 6.1e-33 113.4 6.4 2.3 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CEP18934.1 - 1.2e-07 31.9 107.9 0.00016 21.8 34.8 3.2 1 1 2 3 3 3 2 Nucleoporin FG repeat region PsiB PF06290.6 CEP18934.1 - 0.049 13.0 0.1 0.36 10.2 0.0 2.4 2 0 0 2 2 2 0 Plasmid SOS inhibition protein (PsiB) V_ATPase_I PF01496.14 CEP18934.1 - 0.37 8.5 5.5 0.63 7.8 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 CEP18934.1 - 0.55 10.5 11.2 14 6.0 0.2 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Coiled-coil_56 PF09813.4 CEP18935.1 - 0.0021 18.0 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF423 PF04241.10 CEP18935.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DDE_3 PF13358.1 CEP18938.1 - 1.9e-27 95.7 0.1 1.4e-15 57.2 0.0 3.1 2 2 1 3 3 3 2 DDE superfamily endonuclease SIN1 PF05422.7 CEP18939.1 - 1.3e-51 175.7 2.0 1.1e-32 113.3 0.1 2.2 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) Flu_B_M2 PF04772.7 CEP18940.1 - 0.058 13.4 0.5 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) WHEP-TRS PF00458.15 CEP18940.1 - 0.17 11.5 0.7 0.48 10.1 0.5 1.7 1 0 0 1 1 1 0 WHEP-TRS domain Fib_alpha PF08702.5 CEP18940.1 - 1.6 8.8 13.8 5.1 7.2 5.5 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family ASF1_hist_chap PF04729.8 CEP18941.1 - 7.7e-68 226.9 1.4 9.2e-68 226.7 1.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0172 PF03665.8 CEP18941.1 - 0.053 13.0 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Cys_Met_Meta_PP PF01053.15 CEP18942.1 - 4.7e-157 522.2 0.1 5.3e-157 522.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CEP18942.1 - 4.7e-06 25.6 0.1 8.3e-05 21.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CEP18942.1 - 8.7e-06 25.0 0.5 6e-05 22.2 0.0 2.1 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CEP18942.1 - 7.4e-05 21.8 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEP18942.1 - 0.002 17.3 0.2 0.006 15.7 0.1 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.8 CEP18942.1 - 0.034 12.8 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 Allinase GDC-P PF02347.11 CEP18942.1 - 0.088 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein AhpC-TSA PF00578.16 CEP18943.1 - 4.7e-35 119.9 0.1 5.8e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEP18943.1 - 2.1e-16 59.8 0.0 2.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CEP18943.1 - 0.0004 20.2 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Rcd1 PF04078.8 CEP18944.1 - 9e-130 431.1 1.0 9e-130 431.1 0.7 1.8 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like Mre11_DNA_bind PF04152.9 CEP18944.1 - 0.18 11.6 2.6 7.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain Pkinase PF00069.20 CEP18945.1 - 3.3e-57 193.5 0.2 5.6e-57 192.8 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP18945.1 - 1.2e-41 142.5 0.2 2e-41 141.8 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP18945.1 - 0.0073 15.3 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4445 PF14574.1 CEP18945.1 - 0.095 10.9 0.4 0.15 10.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) Ras PF00071.17 CEP18946.1 - 5.2e-57 191.7 0.7 6e-57 191.5 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP18946.1 - 3.5e-20 72.6 0.1 5.4e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP18946.1 - 8.3e-07 28.4 0.0 9.7e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP18946.1 - 5.7e-06 25.9 0.1 1e-05 25.0 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP18946.1 - 0.00059 19.7 0.0 0.00098 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEP18946.1 - 0.041 13.0 0.1 0.092 11.9 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 CEP18946.1 - 0.064 13.4 0.1 1.7 8.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF881 PF05949.7 CEP18946.1 - 0.069 12.5 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) BING4CT PF08149.6 CEP18947.1 - 1.3e-38 130.3 0.0 2e-37 126.5 0.0 2.9 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 CEP18947.1 - 1.7e-11 43.5 0.0 2.2e-07 30.4 0.0 5.5 7 0 0 7 7 7 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CEP18947.1 - 2.1e-05 23.5 0.0 3.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region PQQ_2 PF13360.1 CEP18947.1 - 0.0088 15.5 0.0 0.059 12.8 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain CotH PF08757.6 CEP18949.1 - 9.2e-49 166.4 3.7 4.6e-48 164.1 2.7 2.0 2 0 0 2 2 2 1 CotH protein Pam16 PF03656.8 CEP18949.1 - 3.2e-16 59.2 10.0 9.5e-16 57.7 5.4 2.6 2 1 0 2 2 2 1 Pam16 Synaptobrevin PF00957.16 CEP18950.1 - 5.5e-34 115.6 1.1 7.9e-34 115.1 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CEP18950.1 - 1.5e-28 98.2 0.0 2.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Glyco_hydro_17 PF00332.13 CEP18951.1 - 1.9e-08 33.7 0.3 1.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 MRP-S28 PF10213.4 CEP18952.1 - 3.4e-39 133.8 1.4 3.8e-39 133.6 0.3 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein HTH_44 PF14641.1 CEP18952.1 - 0.00072 19.5 0.8 0.82 9.6 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix DNA-binding domain of SPT6 DUF3461 PF11944.3 CEP18952.1 - 0.038 13.8 0.9 0.32 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) FBP PF07299.6 CEP18952.1 - 0.12 11.7 1.3 0.35 10.1 0.1 2.0 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) DUF3484 PF11983.3 CEP18953.1 - 0.015 16.0 5.8 0.021 15.6 0.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) ComZ PF10815.3 CEP18953.1 - 0.033 13.9 1.4 4.6 7.0 0.9 2.4 1 1 1 2 2 2 0 ComZ DUF1641 PF07849.6 CEP18953.1 - 0.04 13.5 0.1 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Amidase PF01425.16 CEP18953.1 - 0.12 11.2 0.2 0.23 10.2 0.1 1.4 1 1 0 1 1 1 0 Amidase DAO PF01266.19 CEP18953.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase ORC6 PF05460.8 CEP18954.1 - 0.24 10.4 5.0 0.25 10.3 3.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pneumo_att_G PF05539.6 CEP18954.1 - 0.34 10.2 8.6 0.49 9.7 6.0 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF572 PF04502.8 CEP18954.1 - 0.77 8.9 3.5 1 8.5 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RPE65 PF03055.10 CEP18955.1 - 8.8e-76 255.4 0.0 1.3e-75 254.8 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Acetyltransf_1 PF00583.19 CEP18956.1 - 6.8e-14 51.6 0.0 1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP18956.1 - 7.8e-12 45.1 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP18956.1 - 1.2e-11 44.8 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP18956.1 - 1.1e-07 31.5 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 CEP18956.1 - 4.1e-07 30.0 0.0 5.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP18956.1 - 1.3e-05 25.3 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP18956.1 - 5e-05 23.1 0.1 8.2e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CEP18956.1 - 0.00043 19.8 0.0 0.00059 19.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEP18956.1 - 0.0058 16.5 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEP18956.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 CEP18957.1 - 4.4e-10 39.5 0.0 5.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP18957.1 - 4.6e-08 32.9 0.0 6.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP18957.1 - 9.7e-07 28.9 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CEP18957.1 - 0.00011 21.8 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP18957.1 - 0.00011 22.0 0.0 0.00055 19.7 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP18957.1 - 0.00043 19.9 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CEP18957.1 - 0.0061 16.4 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 CEP18957.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Orthopox_A47 PF06334.6 CEP18957.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A47 protein F1F0-ATPsyn_F PF10791.4 CEP18958.1 - 6.9e-29 99.9 0.1 8.3e-29 99.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 CEP18958.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f RTC4 PF14474.1 CEP18959.1 - 5.1e-19 68.4 0.0 9.5e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain NGP1NT PF08153.7 CEP18961.1 - 3.1e-51 172.6 0.2 3.1e-51 172.6 0.1 2.1 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CEP18961.1 - 7.2e-19 67.8 0.1 3.8e-14 52.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.16 CEP18961.1 - 2.9e-05 23.3 0.1 0.044 13.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 CEP18961.1 - 0.00017 20.8 0.0 0.0032 16.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CEP18961.1 - 0.0011 18.4 0.0 0.27 10.6 0.0 3.6 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEP18961.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_transf_5 PF08323.6 CEP18961.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Dynamin_N PF00350.18 CEP18961.1 - 0.21 11.3 14.0 0.97 9.2 0.0 4.6 4 1 1 5 5 5 0 Dynamin family Rsc14 PF08586.5 CEP18961.1 - 2.1 8.8 5.4 2.2 8.7 1.5 2.7 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit L51_S25_CI-B8 PF05047.11 CEP18962.1 - 1.7e-11 43.6 0.0 2.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Vac7 PF12751.2 CEP18963.1 - 2.9e-12 46.1 7.5 1.5e-07 30.6 2.9 3.3 2 1 0 2 2 2 2 Vacuolar segregation subunit 7 adh_short PF00106.20 CEP18963.1 - 0.0062 16.4 1.2 0.012 15.5 0.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP18963.1 - 0.028 14.2 0.9 0.15 11.8 0.1 1.9 1 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Glycos_transf_2 PF00535.21 CEP18964.1 - 8.7e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CEP18964.1 - 0.00012 21.9 0.4 0.0048 16.7 0.1 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Bromodomain PF00439.20 CEP18965.1 - 2.6e-130 424.6 9.7 4.6e-23 80.9 0.3 7.0 6 0 0 6 6 6 6 Bromodomain Peptidase_M1 PF01433.15 CEP18965.1 - 2.5e-11 43.3 1.6 0.0011 18.0 0.0 4.2 3 1 1 4 4 4 3 Peptidase family M1 zf-CHCC PF10276.4 CEP18966.1 - 3.2e-16 58.8 2.4 4.5e-16 58.3 1.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain TPR_11 PF13414.1 CEP18967.1 - 2.2e-14 52.8 5.7 1.2e-11 44.0 0.5 2.8 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CEP18967.1 - 6.2e-09 35.0 6.8 0.0085 15.6 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEP18967.1 - 9.7e-06 25.1 7.9 0.12 12.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP18967.1 - 0.0029 17.4 1.8 1.4 8.9 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat UBA PF00627.26 CEP18967.1 - 0.0098 15.7 0.2 0.0098 15.7 0.1 2.6 3 0 0 3 3 3 1 UBA/TS-N domain TPR_16 PF13432.1 CEP18967.1 - 0.012 16.3 2.5 0.26 12.0 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 CEP18967.1 - 0.031 14.0 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 DnaJ domain Ribosomal_S8e PF01201.17 CEP18968.1 - 1e-39 135.7 8.2 9.3e-39 132.5 5.7 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e Herpes_UL3 PF03369.8 CEP18968.1 - 0.048 13.6 1.6 0.076 12.9 1.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL3 protein Mito_carr PF00153.22 CEP18969.1 - 1.8e-54 181.4 0.9 2.1e-21 75.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Fumarate_red_D PF02313.12 CEP18969.1 - 0.069 13.0 0.1 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Fumarate reductase subunit D DUF2268 PF10026.4 CEP18969.1 - 0.11 11.9 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) Abhydrolase_3 PF07859.8 CEP18970.1 - 2.4e-24 86.1 0.0 3.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEP18970.1 - 1.1e-09 37.4 0.0 3.6e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CEP18970.1 - 0.0041 16.8 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEP18970.1 - 0.016 14.4 0.0 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3661 PF12400.3 CEP18971.1 - 5.4e-38 130.0 10.7 7.5e-38 129.5 7.4 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Zip PF02535.17 CEP18971.1 - 0.019 14.0 0.0 0.026 13.5 0.0 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter DEAD PF00270.24 CEP18972.1 - 1.6e-39 135.0 0.0 4.5e-39 133.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP18972.1 - 2.4e-20 72.1 0.0 7e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ATP_bind_3 PF01171.15 CEP18972.1 - 9.1e-18 64.3 0.0 1.8e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 PP-loop family ResIII PF04851.10 CEP18972.1 - 2.3e-10 40.5 0.0 2.3e-10 40.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CEP18972.1 - 0.0049 15.7 0.0 0.0095 14.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2392 PF10288.4 CEP18972.1 - 0.023 15.0 0.0 0.073 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) AAA_19 PF13245.1 CEP18972.1 - 0.04 13.6 0.4 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 CEP18972.1 - 0.058 13.5 3.2 0.99 9.5 1.2 3.0 2 1 0 2 2 2 0 AAA domain Fmp27_WPPW PF10359.4 CEP18972.1 - 6.3 5.0 14.4 11 4.3 10.0 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DDHD PF02862.12 CEP18972.1 - 8.4 6.1 10.7 19 4.9 7.4 1.5 1 0 0 1 1 1 0 DDHD domain Surp PF01805.15 CEP18973.1 - 0.032 13.8 0.0 0.073 12.7 0.0 1.7 1 0 0 1 1 1 0 Surp module Enterotoxin_ST PF02048.11 CEP18973.1 - 0.51 10.6 0.1 0.51 10.6 0.0 2.3 2 1 0 2 2 2 0 Heat-stable enterotoxin ST Transposase_21 PF02992.9 CEP18974.1 - 2.4e-08 33.3 0.0 3.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 GreA_GreB_N PF03449.10 CEP18975.1 - 0.084 12.9 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Beta-lactamase PF00144.19 CEP18976.1 - 2.4e-06 26.8 0.0 3.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 CEP18976.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family Beta-lactamase2 PF13354.1 CEP18977.1 - 2.5e-26 92.3 0.0 3.4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.19 CEP18977.1 - 7.9e-18 64.5 0.0 1.8e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 CEP18977.1 - 2.3e-08 33.6 0.0 3.1e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Grp1_Fun34_YaaH PF01184.14 CEP18980.1 - 1.2e-25 90.0 17.9 1.6e-25 89.6 12.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF485 PF04341.7 CEP18980.1 - 0.5 10.1 9.0 1.1 8.9 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ABC2_membrane PF01061.19 CEP18981.1 - 1.8e-88 295.2 69.3 3.5e-49 166.8 12.1 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 CEP18981.1 - 1.4e-37 129.0 0.0 3.7e-21 75.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CEP18981.1 - 1.6e-28 98.4 5.8 5.5e-22 77.3 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 CEP18981.1 - 7.9e-12 44.8 53.9 2.7e-06 26.6 16.9 3.6 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 CEP18981.1 - 6.4e-11 42.1 0.1 1.4e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 CEP18981.1 - 3e-06 27.4 0.2 0.066 13.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEP18981.1 - 1.3e-05 24.6 0.5 0.0079 15.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 CEP18981.1 - 1.7e-05 24.1 0.1 0.00054 19.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP18981.1 - 2e-05 24.7 0.2 0.096 12.8 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_25 PF13481.1 CEP18981.1 - 0.00021 20.7 0.5 0.0087 15.4 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEP18981.1 - 0.00041 20.6 0.0 0.7 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CEP18981.1 - 0.00052 20.0 0.1 0.59 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 CEP18981.1 - 0.00077 19.3 0.0 0.63 9.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 CEP18981.1 - 0.001 18.5 0.1 0.095 12.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 CEP18981.1 - 0.0041 17.9 0.0 0.69 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEP18981.1 - 0.01 15.2 0.3 0.6 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 CEP18981.1 - 0.017 14.8 0.6 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain MMR_HSR1 PF01926.18 CEP18981.1 - 0.029 14.3 0.3 15 5.6 0.0 3.1 2 1 1 3 3 3 0 50S ribosome-binding GTPase UPF0079 PF02367.12 CEP18981.1 - 0.038 13.6 0.7 0.29 10.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CEP18981.1 - 0.06 13.0 0.0 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 CEP18981.1 - 0.07 13.0 2.3 0.38 10.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CEP18981.1 - 0.077 12.6 0.4 4.4 6.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 CEP18981.1 - 0.081 12.4 0.4 2 7.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_2 PF12679.2 CEP18981.1 - 0.098 11.4 24.2 0.014 14.2 1.2 2.8 3 0 0 3 3 2 0 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.13 CEP18981.1 - 0.1 12.0 0.1 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 CEP18981.1 - 0.11 12.9 0.0 6.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 CEP18981.1 - 0.21 10.6 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 CEP18981.1 - 0.22 11.0 0.2 5.4 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CEP18981.1 - 0.22 11.7 0.1 24 5.1 0.1 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 CEP18981.1 - 0.29 10.1 0.0 5 6.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 CEP18981.1 - 0.63 10.3 2.8 0.93 9.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain E1_DerP2_DerF2 PF02221.10 CEP18984.1 - 2.7e-16 60.0 0.1 3.1e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CEP18984.1 - 0.044 13.8 0.1 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 ML-like domain DUF4625 PF15418.1 CEP18984.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) zf-H2C2_2 PF13465.1 CEP18985.1 - 6.9e-25 86.0 23.2 6.4e-08 32.5 0.1 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP18985.1 - 9.3e-18 63.4 33.6 4.4e-05 23.5 2.2 4.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP18985.1 - 4.2e-13 48.6 27.5 0.0018 18.4 1.9 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP18985.1 - 6.4e-05 22.9 6.1 0.61 10.3 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP18985.1 - 0.00043 20.3 5.1 5.6 7.3 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CEP18985.1 - 0.0048 16.7 13.5 0.4 10.6 0.2 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger Ogr_Delta PF04606.7 CEP18985.1 - 0.016 14.8 5.1 1 9.0 0.6 3.2 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger zf-TRAF PF02176.13 CEP18985.1 - 0.086 13.2 10.8 0.7 10.3 0.4 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger zf-CGNR PF11706.3 CEP18985.1 - 9.6 5.8 7.6 25 4.4 2.4 3.3 2 1 0 2 2 2 0 CGNR zinc finger DUF3924 PF13062.1 CEP18986.1 - 0.018 14.9 0.7 0.034 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) SieB PF14163.1 CEP18987.1 - 0.048 13.2 0.1 0.06 12.9 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF896 PF05979.7 CEP18987.1 - 4.5 6.9 8.5 1.7 8.3 4.1 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Ribosomal_S27 PF01599.14 CEP18988.1 - 1.2e-27 95.5 2.3 1.9e-27 94.8 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 CEP18988.1 - 3.6e-13 48.6 0.0 6.4e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CEP18988.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 CEP18988.1 - 0.014 15.2 0.6 0.019 14.8 0.4 1.3 1 0 0 1 1 1 0 IBR domain Telomere_Sde2 PF13019.1 CEP18988.1 - 0.062 12.9 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Telomere stability and silencing CRC_subunit PF08624.5 CEP18989.1 - 5.4e-23 81.4 4.1 6.3e-20 71.5 0.3 2.6 2 1 1 3 3 3 2 Chromatin remodelling complex Rsc7/Swp82 subunit PBP1_TM PF14812.1 CEP18989.1 - 1.4 9.2 13.2 0.14 12.4 0.3 2.8 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UQ_con PF00179.21 CEP18990.1 - 1.3e-50 170.5 0.0 1.4e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Hydrolase_3 PF08282.7 CEP18991.1 - 5e-55 186.8 0.0 5.8e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CEP18991.1 - 3.9e-13 49.2 0.0 2.6e-06 26.9 0.0 2.6 2 1 1 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CEP18991.1 - 5.8e-07 30.1 0.1 0.3 11.4 0.0 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP18991.1 - 1.3e-05 25.4 0.1 0.0013 18.8 0.0 2.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 CEP18991.1 - 0.0017 17.3 0.0 0.61 8.9 0.0 2.4 2 1 0 2 2 2 2 Trehalose-phosphatase Hydrolase_6 PF13344.1 CEP18991.1 - 0.0048 16.7 0.0 0.015 15.2 0.0 1.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP18991.1 - 0.021 15.0 0.0 8.7 6.5 0.0 3.3 1 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase DUF4132 PF13569.1 CEP18991.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) Pkinase PF00069.20 CEP18992.1 - 3.5e-62 209.9 2.9 7e-59 199.0 0.0 3.8 2 1 1 3 3 3 2 Protein kinase domain Ribosomal_L4 PF00573.17 CEP18992.1 - 5e-44 149.9 1.2 5e-44 149.9 0.8 2.4 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CEP18992.1 - 1.5e-29 101.6 1.8 9.4e-29 99.1 1.3 2.5 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Pkinase_Tyr PF07714.12 CEP18992.1 - 3.1e-29 101.8 0.0 2.1e-27 95.8 0.0 2.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP18992.1 - 1.9e-07 30.3 0.0 3.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 CEP18992.1 - 3e-06 26.5 0.0 5.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 CEP18992.1 - 0.02 13.9 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP18992.1 - 0.046 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_72 PF03198.9 CEP18993.1 - 1.7e-133 444.4 1.4 2.2e-133 444.1 0.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CEP18993.1 - 5.4e-12 46.0 0.7 1.9e-11 44.2 0.5 2.0 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 CEP18993.1 - 0.00076 18.7 0.2 0.012 14.8 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.3 CEP18993.1 - 0.0035 16.8 0.1 0.023 14.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core ATP-synt_ab PF00006.20 CEP18994.1 - 9.2e-64 214.8 0.0 1.9e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEP18994.1 - 1.8e-24 86.3 1.0 3.1e-24 85.6 0.7 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEP18994.1 - 3.9e-24 84.6 2.4 8.3e-24 83.5 1.2 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain MobB PF03205.9 CEP18994.1 - 0.0023 17.6 0.1 0.92 9.2 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CEP18994.1 - 0.0033 17.1 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CEP18994.1 - 0.0055 16.3 0.1 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CEP18994.1 - 0.011 15.7 0.3 0.033 14.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 CEP18994.1 - 0.016 14.2 0.1 0.034 13.2 0.1 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 CEP18994.1 - 0.018 13.8 0.9 0.034 13.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 CEP18994.1 - 0.036 14.2 0.1 0.46 10.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CEP18994.1 - 0.037 13.4 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CEP18994.1 - 0.039 14.1 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CEP18994.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CEP18994.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SNARE_assoc PF09335.6 CEP18995.1 - 2.3e-10 40.7 5.0 2.3e-10 40.7 3.5 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Med14 PF08638.6 CEP18996.1 - 6.7e-44 149.4 1.8 3.7e-27 94.8 0.1 2.4 1 1 1 2 2 2 2 Mediator complex subunit MED14 zf-DHHC PF01529.15 CEP18996.1 - 9.4e-39 132.5 5.1 2.2e-38 131.4 3.5 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Tim17 PF02466.14 CEP18997.1 - 5.6e-26 91.0 8.5 8.9e-26 90.4 5.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family C2 PF00168.25 CEP18998.1 - 2.6e-71 235.4 5.2 2.7e-19 68.7 0.0 5.6 5 0 0 5 5 5 5 C2 domain Thioredoxin PF00085.15 CEP18999.1 - 3e-09 36.4 0.0 1.6e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin Oxidored_FMN PF00724.15 CEP19000.1 - 1.2e-103 346.7 0.0 1.3e-103 346.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 CEP19000.1 - 0.0049 16.4 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 Tautomerase enzyme TPP_enzyme_N PF02776.13 CEP19001.1 - 1.9e-32 112.1 0.0 3.3e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CEP19001.1 - 3e-22 78.8 0.0 8.6e-22 77.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CEP19001.1 - 4.3e-18 65.3 0.0 2.1e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Proteasome PF00227.21 CEP19002.1 - 1.2e-52 178.0 0.0 1.5e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEP19002.1 - 1.7e-11 43.1 0.0 3.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF4083 PF13314.1 CEP19003.1 - 0.00018 21.2 0.4 0.00027 20.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) DUF1191 PF06697.7 CEP19003.1 - 0.003 16.4 0.0 0.0034 16.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Pox_A14 PF05767.7 CEP19003.1 - 0.0065 16.4 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 DUF2970 PF11174.3 CEP19003.1 - 0.014 14.9 0.2 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) EssA PF10661.4 CEP19003.1 - 0.022 14.4 0.2 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF912 PF06024.7 CEP19003.1 - 0.033 14.2 0.1 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 CEP19003.1 - 0.047 13.4 0.1 0.057 13.1 0.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family Gypsy PF07253.6 CEP19003.1 - 0.048 11.9 0.0 0.053 11.8 0.0 1.0 1 0 0 1 1 1 0 Gypsy protein Flu_M2 PF00599.12 CEP19003.1 - 0.15 11.9 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M2) EphA2_TM PF14575.1 CEP19003.1 - 0.17 12.2 0.8 0.33 11.3 0.1 1.7 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PfkB PF00294.19 CEP19004.1 - 4.3e-41 141.0 0.4 5.8e-41 140.5 0.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CEP19004.1 - 0.00081 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1183 PF06682.7 CEP19004.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) CcmD PF04995.9 CEP19004.1 - 0.047 13.4 0.5 0.097 12.4 0.3 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NPCBM_assoc PF10633.4 CEP19005.1 - 0.0012 18.7 0.0 1.4 8.9 0.0 2.6 2 1 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase A2M_N PF01835.14 CEP19005.1 - 0.013 15.7 0.1 0.02 15.1 0.1 1.4 1 1 0 1 1 1 0 MG2 domain DUF4625 PF15418.1 CEP19005.1 - 0.016 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) E1_DerP2_DerF2 PF02221.10 CEP19005.1 - 0.038 14.2 0.2 0.062 13.5 0.1 1.6 1 1 0 1 1 1 0 ML domain ADH_zinc_N PF00107.21 CEP19006.1 - 6.6e-27 93.6 0.1 1.3e-26 92.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP19006.1 - 4e-15 56.8 0.0 1e-14 55.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP19006.1 - 3.9e-13 49.1 0.4 1.1e-12 47.6 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 CEP19006.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Biotin_lipoyl_2 PF13533.1 CEP19006.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like rve PF00665.21 CEP19007.1 - 7e-14 51.9 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP19007.1 - 1.1e-10 40.9 0.7 2.6e-10 39.7 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1775 PF07987.6 CEP19011.1 - 3.7e-25 88.4 0.1 5.2e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) EF-hand_1 PF00036.27 CEP19014.1 - 6.8e-25 84.4 17.3 5.1e-08 31.6 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEP19014.1 - 2.7e-22 78.6 5.4 4.5e-12 45.9 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEP19014.1 - 9e-19 65.6 11.2 3.4e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CEP19014.1 - 1.5e-17 62.0 18.1 2.2e-06 26.7 0.2 4.7 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 CEP19014.1 - 4.2e-13 48.7 19.0 1.1e-05 24.9 0.9 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CEP19014.1 - 5.5e-06 26.3 0.0 0.004 17.1 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEP19014.1 - 2.5e-05 23.9 9.4 0.0035 17.0 0.2 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CEP19014.1 - 0.013 15.4 0.1 0.64 9.9 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain AICARFT_IMPCHas PF01808.13 CEP19015.1 - 1e-116 389.4 0.3 1.8e-116 388.6 0.2 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CEP19015.1 - 8.8e-26 89.6 0.1 2.8e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 MGS-like domain SET PF00856.23 CEP19018.1 - 2.3e-27 96.2 0.7 1.1e-26 94.1 0.5 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 CEP19018.1 - 3.7e-17 62.4 3.2 3.7e-17 62.4 2.2 2.5 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 CEP19018.1 - 2.2e-07 30.4 0.0 5.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Imm18 PF15566.1 CEP19018.1 - 0.045 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 18 mRNA_cap_enzyme PF01331.14 CEP19019.1 - 2.9e-34 118.4 0.1 8.8e-18 64.6 0.0 2.4 1 1 1 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CEP19019.1 - 1.8e-11 44.3 0.0 1.8e-11 44.3 0.0 4.1 5 2 0 5 5 5 1 mRNA capping enzyme, C-terminal domain NNMT_PNMT_TEMT PF01234.12 CEP19020.1 - 0.12 11.3 0.1 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Mito_fiss_reg PF05308.6 CEP19020.1 - 1.9 7.8 10.5 0.86 8.9 5.6 1.6 1 1 1 2 2 2 0 Mitochondrial fission regulator MULE PF10551.4 CEP19022.1 - 5.6e-09 36.0 0.9 7.1e-08 32.5 0.2 2.3 1 1 1 2 2 2 1 MULE transposase domain FAR1 PF03101.10 CEP19022.1 - 0.022 15.2 0.8 0.052 14.0 0.6 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain GTP_EFTU PF00009.22 CEP19024.1 - 1.7e-40 138.4 2.6 1.7e-40 138.4 1.8 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CEP19024.1 - 3.1e-28 97.8 2.5 8.9e-28 96.3 1.7 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CEP19024.1 - 2.1e-16 59.7 3.9 1.3e-07 31.6 0.1 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEP19024.1 - 3e-08 33.6 0.1 1.2e-07 31.6 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CEP19024.1 - 4e-06 27.3 2.6 1.2e-05 25.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 CEP19024.1 - 9e-05 21.7 0.6 0.00037 19.7 0.1 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.4 CEP19024.1 - 0.0038 16.7 0.2 0.011 15.2 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CEP19024.1 - 0.0065 15.6 0.0 0.0065 15.6 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 CEP19024.1 - 0.078 12.6 8.3 1.6 8.4 0.0 3.3 3 0 0 3 3 3 0 Elongation factor Tu domain 4 MobB PF03205.9 CEP19024.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.5 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CEP19024.1 - 0.25 11.1 9.7 3 7.6 0.0 4.2 3 1 1 4 4 4 0 Dynamin family RNase_P_p30 PF01876.11 CEP19025.1 - 7.3e-40 135.6 0.1 1.3e-39 134.8 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit p30 Tom37 PF10568.4 CEP19026.1 - 4.3e-07 30.0 0.1 2.1e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 CEP19026.1 - 0.00016 22.1 0.1 0.00056 20.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEP19026.1 - 0.00062 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 CEP19026.1 - 0.011 15.6 1.7 1.9 8.3 0.7 2.3 1 1 1 2 2 2 0 Tom37 C-terminal domain Ribosomal_L18e PF00828.14 CEP19027.1 - 8.2e-31 107.0 1.4 1.5e-30 106.1 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 ubiquitin PF00240.18 CEP19028.1 - 1.6e-35 120.2 3.8 2.8e-33 113.1 0.7 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CEP19028.1 - 1.9e-21 75.4 2.8 6.1e-19 67.4 0.5 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEP19028.1 - 1.5e-05 25.1 0.2 7.3e-05 22.9 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CEP19028.1 - 0.00013 21.6 0.1 0.00029 20.5 0.1 1.5 1 1 1 2 2 2 1 Telomere stability and silencing DUF2407 PF10302.4 CEP19028.1 - 0.0093 16.1 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Tash_PEST PF07708.6 CEP19028.1 - 0.054 13.4 9.0 1.1 9.2 1.2 2.5 2 0 0 2 2 2 0 Tash protein PEST motif CTDII PF01556.13 CEP19028.1 - 0.2 11.5 1.8 9.8 6.1 0.2 2.2 1 1 1 2 2 2 0 DnaJ C terminal domain Ebp2 PF05890.7 CEP19029.1 - 1.2e-73 247.7 28.7 1.2e-73 247.7 19.9 1.4 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Daxx PF03344.10 CEP19029.1 - 0.063 11.7 26.5 0.075 11.5 18.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF4600 PF15372.1 CEP19030.1 - 0.067 13.4 1.5 0.12 12.6 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) tRNA_m1G_MT PF01746.16 CEP19031.1 - 4.3e-29 101.4 0.4 1.1e-28 100.1 0.3 1.6 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Cyt_c_ox_IV PF12270.3 CEP19032.1 - 0.00012 21.8 0.1 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV RCR PF12273.3 CEP19032.1 - 0.00028 21.4 0.5 0.00039 20.9 0.4 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.1 CEP19032.1 - 0.0042 16.8 0.0 0.0049 16.6 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 WBP-1 PF11669.3 CEP19032.1 - 0.017 15.2 0.0 0.017 15.2 0.0 1.6 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF4051 PF13260.1 CEP19032.1 - 0.07 12.4 0.4 0.098 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) CcmH PF03918.9 CEP19032.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein PROL5-SMR PF15621.1 CEP19032.1 - 0.13 12.6 3.1 0.21 12.0 2.2 1.3 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family zf-H2C2_2 PF13465.1 CEP19033.1 - 2.6e-11 43.2 9.1 3.2e-08 33.4 0.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEP19033.1 - 6.3e-06 26.2 14.6 0.0011 19.1 0.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CEP19033.1 - 0.017 15.0 2.8 0.053 13.4 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CEP19033.1 - 0.068 13.5 0.5 0.068 13.5 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4611 PF15387.1 CEP19033.1 - 0.08 13.1 3.1 0.16 12.1 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SNAPc19 PF15497.1 CEP19033.1 - 0.68 10.1 8.4 0.63 10.2 3.1 2.7 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 NUC173 PF08161.7 CEP19034.1 - 2.4e-59 200.0 0.4 1.7e-57 193.9 0.0 3.7 3 0 0 3 3 3 1 NUC173 domain HMG_box_5 PF14887.1 CEP19034.1 - 0.19 11.5 4.7 0.063 13.0 0.4 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Apc5 PF12862.2 CEP19035.1 - 2.2e-18 65.8 9.1 1.4e-14 53.6 0.7 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 CEP19035.1 - 3.7e-05 23.5 0.6 0.008 16.0 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEP19035.1 - 0.0039 16.7 1.3 0.036 13.6 0.1 3.1 4 0 0 4 4 4 1 TPR repeat Interferon PF00143.14 CEP19036.1 - 0.0049 16.7 0.1 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Interferon alpha/beta domain Anth_Ig PF05587.8 CEP19036.1 - 0.099 12.5 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Anthrax receptor extracellular domain RVT_1 PF00078.22 CEP19037.1 - 2.5e-24 85.8 0.1 1e-23 83.8 0.1 2.0 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEP19037.1 - 5e-23 81.4 0.0 4.4e-22 78.4 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 CEP19037.1 - 2.1e-06 27.3 4.4 4.2e-06 26.4 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 CEP19037.1 - 4.8e-06 26.9 0.0 4e-05 24.0 0.0 2.6 3 0 0 3 3 3 1 Aspartyl protease RVP_2 PF08284.6 CEP19037.1 - 0.00028 20.8 0.0 0.00076 19.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.1 CEP19037.1 - 0.00034 20.0 0.0 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.1 CEP19037.1 - 0.0014 18.4 0.0 0.005 16.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CEP19037.1 - 0.012 15.4 0.0 0.05 13.5 0.0 2.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A2B PF12384.3 CEP19037.1 - 0.023 14.0 0.2 3.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Ty3 transposon peptidase zf-CCHC_4 PF14392.1 CEP19037.1 - 0.032 13.9 2.8 0.12 12.1 1.0 2.5 2 0 0 2 2 2 0 Zinc knuckle PIN_2 PF10130.4 CEP19038.1 - 0.83 9.6 5.5 1.1 9.2 3.2 1.5 1 1 0 1 1 1 0 PIN domain Merozoite_SPAM PF07133.6 CEP19038.1 - 1.6 8.6 24.0 0.25 11.2 13.9 1.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF1664 PF07889.7 CEP19038.1 - 2.9 7.6 7.3 16 5.2 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lipase_GDSL PF00657.17 CEP19039.1 - 1.8e-20 73.7 1.9 2.3e-20 73.4 1.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP19039.1 - 1e-05 25.7 1.4 4.7e-05 23.6 1.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.13 CEP19040.1 - 3.7e-43 147.2 0.4 6.9e-43 146.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP19040.1 - 7.8e-10 38.5 10.8 1.8e-09 37.3 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIL PF01843.14 CEP19041.1 - 8.4e-22 77.0 2.3 8.4e-22 77.0 1.6 1.7 2 0 0 2 2 2 1 DIL domain FPL PF09758.4 CEP19041.1 - 0.062 13.0 0.1 1.6 8.4 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein Myosin_head PF00063.16 CEP19042.1 - 1.6e-247 823.0 1.1 1.6e-247 823.0 0.8 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.22 CEP19042.1 - 6e-16 56.4 37.5 1.9e-05 23.9 0.2 7.5 7 0 0 7 7 7 5 IQ calmodulin-binding motif DIL PF01843.14 CEP19042.1 - 7.4e-07 29.0 0.0 3.3e-06 26.9 0.0 2.2 1 0 0 1 1 1 1 DIL domain TPR_MLP1_2 PF07926.7 CEP19042.1 - 0.00026 20.7 20.4 0.018 14.8 6.8 2.7 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein AAA_22 PF13401.1 CEP19042.1 - 0.0065 16.6 0.2 0.029 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEP19042.1 - 0.0093 15.4 0.5 0.11 11.9 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain AAA_19 PF13245.1 CEP19042.1 - 0.064 13.0 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Tropomyosin_1 PF12718.2 CEP19042.1 - 0.32 10.8 23.7 0.82 9.5 16.4 1.7 1 0 0 1 1 1 0 Tropomyosin like CENP-Q PF13094.1 CEP19042.1 - 0.77 9.7 24.0 0.38 10.7 13.9 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 CEP19042.1 - 2 8.2 5.8 1.3 8.8 0.8 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RCR PF12273.3 CEP19044.1 - 0.00047 20.7 0.6 0.0038 17.7 0.4 2.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red PIG-P PF08510.7 CEP19044.1 - 0.017 14.7 0.5 0.073 12.7 0.0 2.2 2 0 0 2 2 2 0 PIG-P IncA PF04156.9 CEP19044.1 - 0.042 13.4 0.3 0.097 12.2 0.2 1.5 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 CEP19044.1 - 0.042 14.2 0.1 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.3 CEP19044.1 - 0.07 13.2 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 WW domain-binding protein 1 YwiC PF14256.1 CEP19044.1 - 0.11 12.5 0.3 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 YwiC-like protein Gastrin PF00918.12 CEP19044.1 - 6.9 7.5 9.1 1.3 9.8 0.1 4.1 4 0 0 4 4 4 0 Gastrin/cholecystokinin family RRM_1 PF00076.17 CEP19046.1 - 4.9e-59 195.8 0.4 8.8e-18 63.7 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP19046.1 - 1.7e-46 156.0 0.1 2.4e-15 56.2 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP19046.1 - 4e-30 103.4 0.1 1.2e-10 41.0 0.0 4.6 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP19046.1 - 0.00029 20.6 6.9 2.1 8.2 0.1 4.3 3 2 0 3 3 3 3 RNA binding motif Nup35_RRM_2 PF14605.1 CEP19046.1 - 0.009 15.7 0.0 6.4 6.6 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif CDC45 PF02724.9 CEP19046.1 - 0.023 12.7 14.6 0.053 11.5 10.1 1.7 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CEP19046.1 - 0.11 10.3 28.0 0.31 8.9 19.4 1.7 1 0 0 1 1 1 0 Nop14-like family ETRAMP PF09716.5 CEP19046.1 - 0.84 9.6 3.4 4.4 7.3 0.2 3.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF866 PF05907.8 CEP19047.1 - 6.4e-51 172.0 6.5 7.1e-51 171.8 4.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 CEP19047.1 - 0.022 14.3 1.5 0.033 13.8 1.0 1.4 1 0 0 1 1 1 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 CEP19047.1 - 0.094 13.0 1.1 0.15 12.4 0.8 1.3 1 0 0 1 1 1 0 Cytochrome c3 zf-CHY PF05495.7 CEP19047.1 - 0.16 12.1 3.3 0.32 11.1 2.3 1.5 1 1 0 1 1 1 0 CHY zinc finger Methyltransf_31 PF13847.1 CEP19048.1 - 1.9e-09 37.3 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP19048.1 - 2.9e-08 34.2 0.0 4.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP19048.1 - 0.00029 20.5 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP19048.1 - 0.00059 20.1 0.0 0.00091 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP19048.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 CEP19048.1 - 0.0056 15.8 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 CEP19048.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 CEP19048.1 - 0.019 15.4 0.1 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CEP19048.1 - 0.021 15.2 0.0 0.032 14.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain N2227 PF07942.7 CEP19048.1 - 0.031 13.2 0.1 1.6 7.5 0.1 2.2 1 1 1 2 2 2 0 N2227-like protein DUF4256 PF14066.1 CEP19048.1 - 0.086 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) Methyltransf_9 PF08003.6 CEP19048.1 - 0.097 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Phage_int_SAM_5 PF13102.1 CEP19048.1 - 0.12 12.3 0.8 0.25 11.3 0.6 1.6 1 1 0 1 1 1 0 Phage integrase SAM-like domain HA2 PF04408.18 CEP19049.1 - 3.5e-31 107.2 0.3 9.2e-31 105.8 0.2 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEP19049.1 - 4.9e-29 100.4 0.0 1.2e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEP19049.1 - 1.6e-11 43.9 0.0 3.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CEP19049.1 - 5.8e-09 35.9 0.3 1.5e-08 34.5 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CEP19049.1 - 7e-07 28.8 0.0 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEP19049.1 - 1.9e-05 24.7 0.1 7.2e-05 22.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain T2SE PF00437.15 CEP19049.1 - 0.0001 21.3 0.1 0.00023 20.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 CEP19049.1 - 0.00068 19.2 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CEP19049.1 - 0.0031 17.0 0.8 0.55 9.6 0.0 3.6 4 0 0 4 4 4 1 AAA-like domain AAA_19 PF13245.1 CEP19049.1 - 0.011 15.4 0.4 0.064 13.0 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain Flavi_DEAD PF07652.9 CEP19049.1 - 0.023 14.4 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.10 CEP19049.1 - 0.027 14.3 0.1 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CEP19049.1 - 0.045 14.0 0.9 1 9.6 0.0 3.1 2 1 0 3 3 3 0 ABC transporter AAA_14 PF13173.1 CEP19049.1 - 0.098 12.5 0.1 1.7 8.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.17 CEP19050.1 - 4.6e-11 42.2 0.1 9e-11 41.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP19050.1 - 1.2e-07 31.6 0.0 3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP19050.1 - 3.2e-05 23.7 0.1 7.2e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HGTP_anticodon2 PF12745.2 CEP19050.1 - 3.7 6.6 13.3 1.8 7.6 0.1 2.9 2 1 1 3 3 3 0 Anticodon binding domain of tRNAs Sod_Cu PF00080.15 CEP19051.1 - 1.1e-50 171.4 3.8 1.3e-50 171.2 2.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 CEP19051.1 - 0.094 13.3 0.4 0.5 10.9 0.1 1.9 1 1 1 2 2 2 0 CHRD domain NAD_binding_10 PF13460.1 CEP19052.1 - 8.6e-12 45.4 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CEP19052.1 - 4.9e-08 32.6 0.1 3.8e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CEP19052.1 - 4.2e-06 26.1 0.0 7.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CEP19052.1 - 1e-05 24.3 0.0 0.00028 19.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CEP19052.1 - 3.3e-05 22.9 0.0 0.0074 15.2 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein TrkA_N PF02254.13 CEP19052.1 - 0.015 15.3 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain Pkinase PF00069.20 CEP19053.1 - 3e-53 180.6 0.0 5.7e-39 133.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19053.1 - 3.8e-18 65.5 0.0 7.5e-18 64.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEP19053.1 - 2.9e-08 33.0 0.0 4.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CEP19053.1 - 2.8e-07 29.7 0.0 4.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP19053.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP19053.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Y_phosphatase PF00102.22 CEP19054.1 - 1.3e-68 230.8 0.3 1.3e-68 230.8 0.2 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 CEP19054.1 - 3.5e-06 26.6 0.4 1.6e-05 24.5 0.1 2.2 2 2 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CEP19054.1 - 6.1e-05 23.3 0.1 0.0002 21.6 0.1 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CEP19054.1 - 6.9e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Myotub-related PF06602.9 CEP19054.1 - 0.06 12.1 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Mito_carr PF00153.22 CEP19055.1 - 1.2e-58 194.7 11.2 4.2e-22 77.6 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein SpoVAD PF07451.6 CEP19055.1 - 0.0056 15.1 0.2 0.0095 14.4 0.2 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Ribosomal_L30_N PF08079.7 CEP19056.1 - 2.3e-18 65.9 9.8 4.4e-18 65.0 6.8 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CEP19056.1 - 4.1e-18 64.6 1.3 1.3e-17 63.0 0.4 2.3 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Phyto_Pns9_10 PF05878.6 CEP19056.1 - 0.0094 14.9 0.6 0.013 14.5 0.4 1.2 1 0 0 1 1 1 1 Phytoreovirus nonstructural protein Pns9/Pns10 DUF3157 PF11355.3 CEP19056.1 - 0.05 12.8 0.8 0.082 12.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Arf PF00025.16 CEP19057.1 - 7.3e-80 266.2 0.1 8.3e-80 266.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CEP19057.1 - 4.9e-13 48.6 0.0 5.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CEP19057.1 - 6.5e-13 48.3 0.0 7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CEP19057.1 - 4.9e-12 45.2 1.5 6.1e-09 35.0 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CEP19057.1 - 5.3e-11 42.1 0.0 6.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP19057.1 - 8.5e-09 35.9 0.0 1.2e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEP19057.1 - 9.7e-06 25.5 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CEP19057.1 - 0.0057 15.7 0.3 0.01 14.8 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CEP19057.1 - 0.059 12.7 0.1 0.49 9.7 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CEP19057.1 - 0.082 12.7 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TPR_11 PF13414.1 CEP19058.1 - 6e-13 48.2 12.9 1.3e-07 31.1 0.0 6.8 6 1 1 7 7 7 2 TPR repeat TPR_2 PF07719.12 CEP19058.1 - 1.3e-09 37.2 19.5 0.092 12.7 0.1 8.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 CEP19058.1 - 1.8e-09 36.8 7.3 0.29 10.8 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP19058.1 - 1.3e-07 31.6 14.2 0.34 11.6 0.0 7.0 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP19058.1 - 1.4e-06 28.5 8.3 0.0045 17.2 0.0 4.4 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEP19058.1 - 2.4e-06 27.3 0.9 0.068 13.3 0.0 6.6 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP19058.1 - 3.4e-06 26.9 0.7 0.0022 17.8 0.0 5.3 5 2 2 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CEP19058.1 - 1.3e-05 25.2 8.4 0.024 14.7 0.0 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CEP19058.1 - 7.6e-05 22.2 7.6 0.8 9.6 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 CEP19058.1 - 0.00016 21.7 2.2 6.3 7.5 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEP19058.1 - 0.00027 21.5 20.4 1.5 9.6 0.0 6.4 6 1 0 7 7 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 CEP19058.1 - 0.00045 20.2 0.9 4.4 7.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEP19058.1 - 0.0036 16.9 7.5 1.5 8.8 0.2 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP19058.1 - 0.005 16.7 11.2 0.069 13.1 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP19058.1 - 0.13 12.8 7.7 2.8 8.5 0.0 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 CEP19059.1 - 2.7e-34 116.9 7.8 3.2e-12 46.2 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP19059.1 - 3e-27 94.5 2.0 1e-10 41.5 0.0 3.2 1 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CEP19059.1 - 1.4e-05 25.0 6.9 0.084 13.0 0.1 4.1 3 2 0 3 3 3 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 CEP19059.1 - 0.0082 16.0 1.0 4 7.3 0.1 3.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.4 CEP19059.1 - 0.6 10.3 4.9 0.75 10.0 0.5 2.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Herpes_TK PF00693.13 CEP19060.1 - 0.054 12.6 1.6 0.073 12.2 1.1 1.1 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus Rotamase_2 PF13145.1 CEP19060.1 - 0.55 10.8 6.2 0.13 12.9 1.1 1.9 2 0 0 2 2 2 0 PPIC-type PPIASE domain Borrelia_P83 PF05262.6 CEP19060.1 - 4.7 5.3 10.5 5.3 5.1 7.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ribosomal_L18p PF00861.17 CEP19061.1 - 1.3e-42 144.7 0.0 2.2e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CEP19061.1 - 7e-29 100.2 3.4 7e-29 100.2 2.4 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region PhoD PF09423.5 CEP19061.1 - 2.2e-08 33.1 0.0 4.6e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase UCH PF00443.24 CEP19062.1 - 1.8e-34 119.0 0.3 2.6e-34 118.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP19062.1 - 6.6e-16 58.6 0.2 8.7e-10 38.5 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ras PF00071.17 CEP19063.1 - 6e-47 159.0 0.5 9.5e-47 158.3 0.3 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CEP19063.1 - 4.7e-15 56.1 0.3 2.2e-14 53.9 0.2 2.0 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CEP19063.1 - 0.00015 21.2 0.3 0.0005 19.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CEP19063.1 - 0.00016 20.9 0.1 0.00025 20.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Sulfotransfer_3 PF13469.1 CEP19064.1 - 5.8e-05 24.0 0.0 7.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family GSCFA PF08885.6 CEP19064.1 - 0.0015 18.1 0.0 0.39 10.2 0.0 2.4 2 1 0 2 2 2 2 GSCFA family Mcp5_PH PF12814.2 CEP19065.1 - 3.2e-26 91.6 0.6 3.2e-26 91.6 0.4 3.1 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.5 CEP19065.1 - 0.022 14.7 1.6 0.068 13.1 0.0 2.4 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH PF00169.24 CEP19065.1 - 0.023 14.8 1.2 0.023 14.8 0.8 3.2 3 0 0 3 3 3 0 PH domain ACR_tran PF00873.14 CEP19065.1 - 5 4.3 11.6 7.4 3.8 8.1 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Ecl1 PF12855.2 CEP19066.1 - 1.3e-08 33.9 3.9 2.2e-08 33.2 2.7 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 CEP19066.1 - 0.04 13.7 0.9 0.04 13.7 0.6 1.7 2 0 0 2 2 2 0 MYND finger HA2 PF04408.18 CEP19067.1 - 1.9e-19 69.5 0.0 5.4e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEP19067.1 - 7.7e-15 54.5 0.1 2e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CEP19067.1 - 3e-14 52.8 0.0 9e-14 51.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 CEP19067.1 - 2.2e-13 50.0 1.1 6.2e-13 48.6 0.8 1.8 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 CEP19067.1 - 8e-07 28.7 1.1 1.7e-06 27.6 0.4 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DND1_DSRM PF14709.1 CEP19067.1 - 0.00014 22.0 0.7 0.00046 20.4 0.1 2.3 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.1 CEP19067.1 - 0.0002 21.5 0.4 0.00081 19.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain UBA PF00627.26 CEP19067.1 - 0.0083 15.9 0.3 0.13 12.1 0.0 3.1 4 0 0 4 4 4 1 UBA/TS-N domain T2SE PF00437.15 CEP19067.1 - 0.017 14.0 0.0 0.046 12.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 CEP19067.1 - 0.034 13.2 0.1 0.079 12.0 0.0 1.5 1 0 0 1 1 1 0 KaiC PG_binding_2 PF08823.6 CEP19067.1 - 0.047 13.8 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain HLH PF00010.21 CEP19068.1 - 2e-16 59.4 4.4 2e-16 59.4 3.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain KAP_NTPase PF07693.9 CEP19068.1 - 0.043 12.7 0.7 0.069 12.1 0.5 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SRRM_C PF15230.1 CEP19068.1 - 6.4 6.9 10.6 0.33 11.0 3.0 2.1 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Mito_carr PF00153.22 CEP19069.1 - 1.1e-69 230.2 2.3 1.3e-23 82.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3158 PF11358.3 CEP19069.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) SQS_PSY PF00494.14 CEP19071.1 - 8e-38 130.2 0.0 1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase RIX1 PF08167.7 CEP19072.1 - 9.2e-33 113.2 6.3 2.6e-31 108.5 1.9 2.9 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis TENA_THI-4 PF03070.11 CEP19072.1 - 0.062 13.0 0.0 1 9.0 0.0 2.4 2 1 0 2 2 2 0 TENA/THI-4/PQQC family TP_methylase PF00590.15 CEP19073.1 - 3.2e-42 144.6 0.0 4.8e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CEP19073.1 - 1.2e-29 102.6 0.1 4.3e-29 100.8 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CEP19073.1 - 1.5e-14 53.0 1.5 3.1e-14 52.0 1.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CEP19073.1 - 7.5e-11 40.8 0.0 1.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central OTCace PF00185.19 CEP19073.1 - 0.0079 16.0 0.0 0.07 13.0 0.0 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 2-Hacid_dh_C PF02826.14 CEP19073.1 - 0.072 12.2 0.1 0.17 11.0 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 CEP19073.1 - 0.09 12.6 0.2 0.24 11.2 0.0 1.8 1 1 1 2 2 2 0 ThiF family ELFV_dehydrog PF00208.16 CEP19073.1 - 0.093 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GTP_EFTU PF00009.22 CEP19074.1 - 2.3e-58 196.7 0.0 3.6e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CEP19074.1 - 8.6e-37 125.3 0.0 2.5e-36 123.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CEP19074.1 - 1.9e-29 101.3 0.0 4.8e-29 100.0 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CEP19074.1 - 1.9e-26 91.7 0.0 4.6e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CEP19074.1 - 3.9e-11 42.9 0.1 1.1e-10 41.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEP19074.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AIG1 PF04548.11 CEP19074.1 - 0.037 13.1 0.0 0.079 12.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family LRR_8 PF13855.1 CEP19075.1 - 0.00059 19.5 2.9 0.0057 16.3 0.2 3.5 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 CEP19075.1 - 0.027 14.1 9.6 0.68 9.6 0.2 5.0 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CEP19075.1 - 0.27 11.4 2.4 41 4.6 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat Phi_1 PF04674.7 CEP19076.1 - 5.4e-30 104.4 0.2 9.2e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region Curlin_rpt PF07012.7 CEP19076.1 - 2.3 7.9 7.3 1.5 8.5 0.9 2.8 3 0 0 3 3 3 0 Curlin associated repeat Podoplanin PF05808.6 CEP19077.1 - 0.14 11.6 4.6 1 8.9 0.1 3.3 4 0 0 4 4 4 0 Podoplanin DUF2077 PF09850.4 CEP19077.1 - 0.19 11.1 1.1 1.1 8.5 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF3899 PF13038.1 CEP19077.1 - 0.58 10.3 0.0 0.58 10.3 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) UPF0233 PF06781.7 CEP19077.1 - 2 8.0 3.7 2 8.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Arf PF00025.16 CEP19078.1 - 1.4e-54 183.9 0.9 1.4e-54 183.9 0.6 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family CotH PF08757.6 CEP19078.1 - 2.8e-35 122.1 9.8 3.7e-29 102.0 2.3 2.4 1 1 1 2 2 2 2 CotH protein Ras PF00071.17 CEP19078.1 - 5.5e-12 45.3 0.5 1.1e-11 44.3 0.3 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CEP19078.1 - 3.2e-11 42.7 0.5 6.3e-11 41.8 0.4 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CEP19078.1 - 2.2e-09 37.8 0.2 5e-09 36.6 0.2 1.7 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 CEP19078.1 - 8.3e-09 34.6 2.1 6.5e-07 28.3 0.2 2.7 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CEP19078.1 - 3.8e-07 30.0 0.2 8.7e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEP19078.1 - 5.4e-07 28.9 0.5 5.4e-07 28.9 0.3 2.0 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 CEP19078.1 - 0.019 14.8 0.6 0.07 13.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CEP19078.1 - 0.64 9.4 3.0 3.9 6.8 0.2 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_S24e PF01282.14 CEP19079.1 - 2.7e-35 119.9 0.1 4.9e-35 119.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e DIM1 PF02966.11 CEP19079.1 - 0.007 15.8 0.3 0.018 14.5 0.1 1.7 1 1 0 1 1 1 1 Mitosis protein DIM1 Zip PF02535.17 CEP19080.1 - 1.9e-66 224.2 18.0 3.3e-66 223.4 12.5 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2160 PF09928.4 CEP19080.1 - 0.4 10.8 3.2 0.75 9.9 0.1 2.9 2 2 1 3 3 3 0 Predicted small integral membrane protein (DUF2160) Tir_receptor_C PF07489.6 CEP19081.1 - 0.037 13.7 2.6 0.043 13.5 1.8 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Methyltransf_4 PF02390.12 CEP19082.1 - 9e-60 201.1 0.0 1.1e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEP19082.1 - 0.00045 20.7 0.0 0.00073 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP19082.1 - 0.0048 17.2 0.0 0.0098 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP19082.1 - 0.0069 15.7 0.0 0.052 12.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CEP19082.1 - 0.0079 15.7 0.0 0.01 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP19082.1 - 0.024 15.0 0.0 0.059 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CEP19082.1 - 0.044 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CEP19082.1 - 0.081 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rieske PF00355.21 CEP19083.1 - 1.9e-08 33.7 0.0 2.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 CEP19083.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Acetyltransf_7 PF13508.1 CEP19084.1 - 1.1e-11 44.7 0.0 3.7e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEP19084.1 - 2.3e-09 37.1 0.0 9.6e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEP19084.1 - 3.8e-06 27.0 0.0 0.0001 22.3 0.0 2.6 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP19084.1 - 1.6e-05 24.5 0.0 3.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CEP19084.1 - 6.8e-05 22.7 0.0 0.0002 21.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP19084.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ste50p-SAM PF09235.5 CEP19084.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif CNH PF00780.17 CEP19085.1 - 1.8e-55 188.3 0.0 2.9e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEP19085.1 - 6.2e-33 114.1 2.2 6.2e-33 114.1 1.5 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 CEP19085.1 - 1.9e-17 63.4 2.9 4.2e-17 62.3 0.0 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CEP19085.1 - 0.00053 20.1 0.0 0.0042 17.2 0.0 2.6 2 0 0 2 2 2 1 PH domain PAS_9 PF13426.1 CEP19086.1 - 1.3e-26 93.0 0.0 5.8e-18 65.1 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 CEP19086.1 - 4.3e-19 68.3 0.0 4.6e-12 45.8 0.0 3.8 3 1 0 3 3 3 3 PAS fold GATA PF00320.22 CEP19086.1 - 5.8e-15 54.3 3.3 1.4e-14 53.1 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 CEP19086.1 - 1.1e-12 47.9 0.0 1.3e-05 25.1 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 CEP19086.1 - 1.2e-09 38.0 0.0 2.3e-05 24.2 0.0 3.9 3 1 0 3 3 3 2 PAS domain PAS PF00989.19 CEP19086.1 - 4e-09 36.2 0.0 0.0034 17.1 0.0 3.9 3 1 0 3 3 3 2 PAS fold LHH PF14411.1 CEP19086.1 - 0.012 15.8 1.2 0.027 14.7 0.0 2.1 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Erp_C PF06780.6 CEP19086.1 - 0.063 13.1 0.5 0.18 11.6 0.2 1.8 2 0 0 2 2 2 0 Erp protein C-terminus Pkinase PF00069.20 CEP19087.1 - 2.7e-69 233.2 0.0 3.1e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19087.1 - 4.1e-27 94.8 0.0 4.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19087.1 - 0.00024 20.1 0.0 0.00055 18.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP19087.1 - 0.011 14.8 0.2 0.02 13.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP19087.1 - 0.056 13.1 0.1 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RelB PF04221.7 CEP19087.1 - 0.13 12.0 0.0 8.9 6.1 0.0 2.3 2 0 0 2 2 2 0 RelB antitoxin Fes1 PF08609.5 CEP19088.1 - 5.6e-20 71.6 1.1 5.6e-20 71.6 0.8 2.0 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 CEP19088.1 - 4.5e-07 30.0 0.2 1.8e-05 24.9 0.0 3.1 3 1 0 3 3 3 1 HEAT repeats Arm PF00514.18 CEP19088.1 - 1.2e-06 28.0 0.0 0.0038 17.0 0.0 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CEP19088.1 - 2.6e-06 27.0 0.0 0.0013 18.6 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 CEP19088.1 - 6.7e-05 21.3 1.0 0.021 13.1 0.2 2.8 1 1 1 3 3 3 1 Adaptin N terminal region Clathrin PF00637.15 CEP19088.1 - 0.0009 18.8 1.1 1.1 8.7 0.1 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS Cnd1 PF12717.2 CEP19088.1 - 0.0044 16.8 0.0 0.029 14.2 0.0 2.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CEP19088.1 - 0.0077 16.6 0.1 0.11 13.0 0.0 2.9 1 1 2 3 3 3 2 HEAT-like repeat V-ATPase_H_C PF11698.3 CEP19088.1 - 0.15 12.0 0.6 11 5.9 0.0 3.0 1 1 1 3 3 3 0 V-ATPase subunit H MRP-S26 PF14943.1 CEP19091.1 - 0.22 11.0 18.7 0.18 11.3 11.7 1.8 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 Homeobox_KN PF05920.6 CEP19092.1 - 1.7e-17 62.8 1.7 1.7e-17 62.8 1.2 2.6 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CEP19092.1 - 7.7e-08 31.8 0.4 1.8e-07 30.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain BTB_2 PF02214.17 CEP19093.1 - 3.1e-14 52.9 2.5 3.3e-14 52.8 0.4 1.9 2 0 0 2 2 2 1 BTB/POZ domain RFC1 PF08519.7 CEP19093.1 - 0.0043 16.8 0.2 0.0095 15.7 0.1 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain CNH PF00780.17 CEP19094.1 - 1e-61 208.7 0.0 5.2e-61 206.4 0.0 2.3 1 1 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEP19094.1 - 2.1e-37 128.7 0.9 2.1e-37 128.7 0.6 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 CEP19094.1 - 6.8e-30 103.7 4.0 1.3e-29 102.8 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain SR-25 PF10500.4 CEP19094.1 - 6.4e-16 58.5 6.6 6.4e-16 58.5 4.6 5.1 4 2 1 5 5 5 1 Nuclear RNA-splicing-associated protein DEP PF00610.16 CEP19094.1 - 3.2e-13 49.2 0.1 6.8e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 CEP19094.1 - 0.0039 17.3 0.0 0.025 14.7 0.0 2.5 2 0 0 2 2 2 1 PH domain DSPc PF00782.15 CEP19095.1 - 4.7e-40 136.2 0.2 3.5e-26 91.3 0.1 2.8 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP19095.1 - 1.1e-06 28.1 0.1 0.0031 16.8 0.1 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CEP19095.1 - 0.048 13.6 0.2 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.7 CEP19095.1 - 0.076 12.4 1.6 12 5.2 0.0 2.9 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HSP70 PF00012.15 CEP19096.1 - 2.5e-09 35.6 0.0 8.9e-09 33.8 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP19096.1 - 0.087 11.4 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Piwi PF02171.12 CEP19097.1 - 5.4e-95 317.8 0.0 7.2e-95 317.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CEP19097.1 - 7.5e-22 77.0 0.1 1.6e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CEP19097.1 - 4e-16 58.0 0.0 1.1e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Band_7 PF01145.20 CEP19098.1 - 2.4e-23 82.9 4.2 3.6e-23 82.4 2.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Fork_head PF00250.13 CEP19099.1 - 1.1e-30 105.4 0.3 2.4e-30 104.4 0.2 1.6 1 0 0 1 1 1 1 Fork head domain Kelch_4 PF13418.1 CEP19100.1 - 5.4e-14 51.6 5.2 0.001 18.8 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP19100.1 - 2.6e-08 33.6 5.6 0.27 11.2 0.2 5.0 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 CEP19100.1 - 3.3e-07 30.2 6.6 0.0038 17.3 0.0 5.8 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CEP19100.1 - 6.7e-05 22.8 4.5 1.2 9.4 0.0 5.4 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 CEP19100.1 - 0.00067 19.3 3.3 0.24 11.2 0.0 4.4 4 1 0 4 4 4 1 Kelch motif Rax2 PF12768.2 CEP19100.1 - 0.049 12.8 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.1 CEP19100.1 - 0.058 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Chordopox_A13L PF05961.6 CEP19100.1 - 0.062 13.2 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ASFV_J13L PF05568.6 CEP19100.1 - 0.069 12.6 0.5 0.15 11.5 0.3 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4604 PF15377.1 CEP19102.1 - 6.3e-19 68.7 22.2 7.5e-19 68.4 15.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2944 PF11161.3 CEP19102.1 - 0.12 12.0 0.3 0.45 10.1 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) Merozoite_SPAM PF07133.6 CEP19102.1 - 0.38 10.6 18.0 0.48 10.2 12.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.8 CEP19102.1 - 6.9 4.2 21.8 0.043 11.5 7.7 1.9 1 1 1 2 2 2 0 DNA polymerase phi TPR_16 PF13432.1 CEP19103.1 - 1.1e-25 89.7 8.7 0.0001 22.8 0.0 7.2 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 CEP19103.1 - 9e-25 86.1 16.4 4.4e-06 26.2 0.0 8.0 7 2 1 9 9 8 6 TPR repeat TPR_2 PF07719.12 CEP19103.1 - 6.5e-24 81.8 11.1 0.02 14.7 0.0 11.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_1 PF00515.23 CEP19103.1 - 1.5e-23 81.3 6.0 0.012 15.2 0.0 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 CEP19103.1 - 6.2e-19 67.7 12.9 1.1e-05 25.3 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CEP19103.1 - 7.9e-19 67.7 18.4 4e-06 27.0 0.4 8.3 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CEP19103.1 - 3e-18 64.1 15.2 0.43 10.4 0.1 10.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.1 CEP19103.1 - 6.7e-18 63.3 8.8 0.0059 16.7 0.0 8.6 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 CEP19103.1 - 4.7e-16 58.0 11.8 0.014 15.8 0.0 10.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP19103.1 - 7e-15 54.1 6.9 0.033 14.8 0.0 9.7 6 2 5 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEP19103.1 - 8.9e-12 43.8 16.1 0.00013 21.4 0.1 8.9 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 CEP19103.1 - 7.4e-09 35.3 0.1 0.05 13.4 0.0 5.3 3 2 3 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CEP19103.1 - 1.7e-07 31.2 13.0 0.0017 18.4 0.0 5.9 7 1 0 7 7 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CEP19103.1 - 6.7e-07 29.0 10.7 0.037 13.9 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 CEP19103.1 - 2.5e-06 27.4 4.5 0.056 13.5 0.6 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat Rapsyn_N PF10579.4 CEP19103.1 - 0.00072 19.3 3.8 0.35 10.7 0.0 4.5 4 1 1 5 5 5 1 Rapsyn N-terminal myristoylation and linker region Alkyl_sulf_dimr PF14863.1 CEP19103.1 - 0.0059 16.8 7.2 8.8 6.5 0.0 5.2 3 2 2 5 5 5 0 Alkyl sulfatase dimerisation DUF3366 PF11846.3 CEP19103.1 - 0.072 12.9 2.4 0.58 10.0 0.0 3.1 4 0 0 4 4 3 0 Domain of unknown function (DUF3366) Peptidase_M28 PF04389.12 CEP19104.1 - 2.5e-36 125.1 0.0 7.8e-36 123.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 CEP19104.1 - 4.8e-05 22.9 0.0 9.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CEP19104.1 - 0.00044 19.1 0.0 0.0017 17.1 0.0 1.9 2 1 1 3 3 3 1 M42 glutamyl aminopeptidase Aa_trans PF01490.13 CEP19105.1 - 2.5e-93 312.7 37.3 3e-93 312.5 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Rhodanese PF00581.15 CEP19106.1 - 9.7e-10 38.7 0.0 2.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Ta0938 PF11494.3 CEP19106.1 - 0.19 11.8 1.9 0.41 10.7 1.3 1.5 1 0 0 1 1 1 0 Ta0938 Myb_DNA-binding PF00249.26 CEP19107.1 - 2.5e-39 133.0 8.2 4.8e-15 55.3 0.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP19107.1 - 8.5e-33 112.2 10.3 1.7e-16 60.0 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CEP19107.1 - 0.00081 19.4 12.1 1.6 8.8 0.2 4.2 2 2 1 3 3 3 3 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 CEP19107.1 - 0.0014 18.4 6.1 0.9 9.4 0.0 3.4 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.11 CEP19108.1 - 2.6e-60 204.0 40.4 6.3e-53 179.7 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP19108.1 - 1.5e-14 53.4 20.0 4.1e-10 38.8 4.8 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter OATP PF03137.15 CEP19108.1 - 0.074 11.0 11.7 0.23 9.4 0.8 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S8 PF00082.17 CEP19109.1 - 8.4e-50 169.4 7.5 1.2e-49 168.9 5.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CEP19109.1 - 0.0004 20.8 0.2 0.0008 19.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pyridoxal_deC PF00282.14 CEP19110.1 - 2.4e-72 243.4 0.0 3.4e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain IMPDH PF00478.20 CEP19111.1 - 1.2e-135 452.0 3.5 1.3e-135 451.8 2.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CEP19111.1 - 1.8e-18 66.0 0.2 2.4e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CEP19111.1 - 4.1e-11 42.3 1.5 1.8e-10 40.1 0.7 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CEP19111.1 - 1.5e-09 37.4 2.7 3.9e-07 29.5 0.6 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 CEP19111.1 - 1.6e-05 24.2 3.6 0.002 17.4 0.1 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 CEP19111.1 - 8.7e-05 21.7 1.6 0.00077 18.6 0.1 2.4 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.9 CEP19111.1 - 0.0017 17.3 0.2 0.0036 16.3 0.2 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 CEP19111.1 - 0.0043 15.9 0.6 1.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) PK PF00224.16 CEP19111.1 - 0.0044 15.6 0.0 0.0096 14.5 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Aldolase PF01081.14 CEP19111.1 - 0.045 12.9 1.2 0.071 12.2 0.1 1.8 2 0 0 2 2 2 0 KDPG and KHG aldolase PcrB PF01884.12 CEP19111.1 - 1.6 7.9 5.1 1.5 7.9 0.3 3.0 3 1 1 4 4 4 0 PcrB family RRM_1 PF00076.17 CEP19112.1 - 1.5e-23 82.1 10.0 1.7e-16 59.5 0.1 4.7 4 1 1 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP19112.1 - 3.3e-16 59.0 4.8 4.2e-12 45.8 0.0 4.0 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP19112.1 - 7.2e-12 44.9 3.1 0.00016 21.4 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEP19112.1 - 0.0044 16.7 0.1 3.8 7.3 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Spo7_2_N PF15407.1 CEP19112.1 - 0.091 12.2 0.0 14 5.2 0.0 3.0 3 0 0 3 3 3 0 Sporulation protein family 7 Mgm101p PF06420.7 CEP19113.1 - 4.2e-90 299.5 0.0 6.2e-90 299.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Autophagy_Cterm PF10381.4 CEP19113.1 - 0.65 9.1 4.2 1.2 8.3 2.9 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Peptidase_M24 PF00557.19 CEP19114.1 - 3.8e-49 167.0 0.1 4.6e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 CEP19114.1 - 0.0012 18.6 2.8 0.0029 17.4 1.9 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 CEP19114.1 - 1.9 8.2 5.1 5.1 6.8 3.6 1.8 1 0 0 1 1 1 0 HIT zinc finger Phage_DNA_bind PF02303.12 CEP19115.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-destabilising protein HNH PF01844.18 CEP19115.1 - 0.067 13.0 0.2 2.1 8.2 0.0 2.7 2 1 0 2 2 2 0 HNH endonuclease DUF3419 PF11899.3 CEP19116.1 - 1.5e-120 402.4 0.1 2.4e-120 401.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 CEP19116.1 - 1.1e-10 41.4 0.0 6.1e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP19116.1 - 1.4e-09 37.7 0.0 1.3e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP19116.1 - 2.8e-09 37.5 0.0 6.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP19116.1 - 1.1e-07 32.1 0.0 4.8e-05 23.7 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP19116.1 - 1.1e-06 29.0 0.0 8.4e-06 26.1 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP19116.1 - 1.4e-06 27.6 0.0 4e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEP19116.1 - 2.1e-05 24.8 0.0 8e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP19116.1 - 0.00013 22.0 0.0 0.0023 17.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP19116.1 - 0.0048 15.9 0.0 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 CEP19116.1 - 0.044 13.3 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF962 PF06127.6 CEP19116.1 - 0.053 13.4 3.8 0.058 13.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF962) RrnaAD PF00398.15 CEP19116.1 - 0.13 11.2 0.0 0.32 9.9 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Homeobox PF00046.24 CEP19117.1 - 2.6e-06 26.9 1.2 6.3e-06 25.7 0.9 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP19117.1 - 0.042 13.5 0.5 0.12 12.0 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain CDC45 PF02724.9 CEP19117.1 - 0.071 11.1 8.6 0.1 10.5 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Lipase_GDSL PF00657.17 CEP19118.1 - 7e-13 48.9 0.2 9.2e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 CEP19119.1 - 1.5e-34 119.2 30.1 4.9e-21 74.8 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_C_3 PF14497.1 CEP19121.1 - 7.5e-07 29.5 0.0 2e-06 28.1 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEP19121.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CEP19121.1 - 1.1e-05 25.5 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP19121.1 - 0.0003 20.9 0.0 0.00089 19.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEP19121.1 - 0.00085 19.1 0.0 0.0042 16.9 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CEP19121.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Las1 PF04031.8 CEP19122.1 - 1.2e-50 171.1 0.7 2.1e-50 170.3 0.5 1.4 1 0 0 1 1 1 1 Las1-like TPR_11 PF13414.1 CEP19123.1 - 0.00064 19.3 1.5 2.9 7.6 0.0 4.0 3 1 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 CEP19123.1 - 0.0034 17.6 4.3 3.5 8.0 0.0 4.9 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP19123.1 - 0.0038 17.7 1.0 5.4 7.9 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP19123.1 - 0.0083 16.0 3.3 1.4 8.9 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TcdA_TcdB PF12919.2 CEP19123.1 - 0.0097 14.4 5.3 0.0062 15.0 1.0 2.2 2 1 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain TPR_1 PF00515.23 CEP19123.1 - 0.012 15.2 5.8 1.9 8.2 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEP19123.1 - 0.03 14.2 4.9 5.8 7.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Spectrin PF00435.16 CEP19123.1 - 0.04 14.2 5.6 0.16 12.3 1.0 2.8 2 0 0 2 2 2 0 Spectrin repeat MIT PF04212.13 CEP19123.1 - 0.73 9.7 12.6 0.29 11.0 0.1 4.2 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 CEP19123.1 - 2.9 7.8 7.4 29 4.7 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF303 PF03629.13 CEP19124.1 - 2.6e-39 134.9 0.0 4.8e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF303) G-alpha PF00503.15 CEP19125.1 - 3.6e-57 193.8 0.0 8.9e-57 192.5 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP19125.1 - 3.1e-07 29.8 0.1 4.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Radical_SAM PF04055.16 CEP19126.1 - 5.5e-38 130.7 0.0 2.3e-37 128.7 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 CEP19126.1 - 4e-22 77.8 0.7 5.5e-21 74.2 0.0 2.4 1 1 1 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 CEP19126.1 - 1.3e-06 28.0 0.2 3.1e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 TRAM domain Complex1_LYR PF05347.10 CEP19127.1 - 6.6e-05 22.6 0.5 0.00025 20.7 0.1 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEP19127.1 - 0.00036 20.6 0.2 0.00073 19.6 0.1 1.7 1 1 0 1 1 1 1 Complex1_LYR-like THDPS_N_2 PF14805.1 CEP19127.1 - 0.13 12.1 0.0 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PAP1 PF08601.5 CEP19128.1 - 2.8e-10 40.4 1.9 2.8e-10 40.4 1.3 3.1 1 1 2 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.16 CEP19128.1 - 1.1e-09 38.1 14.4 2.9e-09 36.7 10.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP19128.1 - 0.00072 19.3 10.4 0.00072 19.3 7.2 2.4 1 1 1 2 2 2 1 Basic region leucine zipper Herpes_DNAp_acc PF04929.7 CEP19128.1 - 0.088 11.7 5.2 0.15 11.0 3.6 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MSV199 PF10553.4 CEP19128.1 - 0.11 12.3 1.8 0.18 11.6 0.5 1.8 2 0 0 2 2 2 0 MSV199 domain TAF8_C PF10406.4 CEP19129.1 - 1.5e-14 53.7 1.7 1.5e-14 53.7 1.1 1.8 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 CEP19129.1 - 4e-14 52.0 0.0 6.4e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DDE_Tnp_4 PF13359.1 CEP19130.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.1 CEP19132.1 - 3.2e-21 75.5 0.0 4.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 CEP19132.1 - 0.0012 18.3 0.1 0.0028 17.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Myb_DNA-bind_5 PF13873.1 CEP19133.1 - 4.1e-05 23.3 0.4 0.0018 18.1 0.1 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CEP19133.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.4 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEP19133.1 - 0.055 13.5 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP19133.1 - 0.076 13.0 0.5 0.44 10.6 0.3 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain GOLD_2 PF13897.1 CEP19134.1 - 2.3 8.4 4.5 0.49 10.6 0.1 2.0 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking AIF_C PF14721.1 CEP19134.1 - 5.9 7.1 5.9 5.1 7.3 0.1 2.3 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4140 PF13600.1 CEP19135.1 - 0.03 14.7 0.4 0.057 13.8 0.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 CEP19135.1 - 0.035 13.9 0.1 0.058 13.2 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_27 PF13514.1 CEP19135.1 - 0.042 11.5 0.2 0.051 11.2 0.2 1.0 1 0 0 1 1 1 0 AAA domain DUF1192 PF06698.6 CEP19135.1 - 0.061 13.1 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DivIC PF04977.10 CEP19135.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator PEP-utilisers_N PF05524.8 CEP19135.1 - 0.08 12.7 0.6 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Myb_DNA-bind_5 PF13873.1 CEP19136.1 - 2.3e-05 24.1 0.6 0.0022 17.8 0.2 2.1 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 CEP19136.1 - 0.055 13.5 0.5 0.32 11.0 0.3 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain muHD PF10291.4 CEP19138.1 - 1.9e-27 96.1 0.7 3.2e-27 95.3 0.5 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CEP19138.1 - 9.8e-13 48.1 0.0 9.8e-13 48.1 0.0 3.1 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Rho_Binding PF08912.6 CEP19138.1 - 4 7.8 10.0 16 5.8 0.9 2.8 1 1 1 2 2 2 0 Rho Binding Muted PF14942.1 CEP19138.1 - 5.7 6.8 11.4 0.31 10.9 3.6 2.1 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein CBM_19 PF03427.8 CEP19140.1 - 6.6e-21 73.8 55.5 1.9e-06 27.5 5.2 4.6 4 0 0 4 4 4 4 Carbohydrate binding domain (family 19) Glyco_hydro_18 PF00704.23 CEP19140.1 - 1.4e-17 64.2 0.6 2.3e-17 63.4 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 EPL1 PF10513.4 CEP19141.1 - 4.7e-32 111.4 3.9 4.7e-32 111.4 2.7 3.1 2 1 0 2 2 2 1 Enhancer of polycomb-like TFIIA PF03153.8 CEP19141.1 - 9.5 6.0 17.8 22 4.8 12.3 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SSrecog PF03531.9 CEP19142.1 - 1.1e-72 243.9 0.9 2.4e-72 242.8 0.6 1.6 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CEP19142.1 - 9.9e-32 108.7 0.1 4.8e-31 106.5 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like RhoGEF PF00621.15 CEP19143.1 - 3.6e-27 95.3 0.1 5.8e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 CEP19143.1 - 0.00085 19.4 0.0 0.0027 17.8 0.0 1.9 2 0 0 2 2 2 1 PH domain Herpes_UL3 PF03369.8 CEP19143.1 - 0.05 13.5 1.1 7.4 6.5 0.2 2.6 2 0 0 2 2 2 0 Herpesvirus UL3 protein ADK PF00406.17 CEP19145.1 - 1.4e-49 167.8 0.1 1.7e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CEP19145.1 - 2.4e-12 47.2 0.2 3.6e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CEP19145.1 - 1.3e-08 34.4 3.4 0.00018 20.9 0.6 2.1 1 1 1 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 CEP19145.1 - 1.6e-08 35.3 0.1 2.4e-08 34.8 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEP19145.1 - 6.4e-07 29.3 0.1 2.9e-06 27.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CEP19145.1 - 5.8e-05 22.2 0.0 8.2e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin NTase_sub_bind PF08780.6 CEP19145.1 - 0.036 13.8 0.6 5.8 6.7 0.0 2.2 1 1 1 2 2 2 0 Nucleotidyltransferase substrate binding protein like dNK PF01712.14 CEP19145.1 - 0.038 13.9 1.2 0.098 12.5 0.8 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.22 CEP19145.1 - 0.064 13.5 0.3 0.28 11.4 0.2 2.0 1 1 0 1 1 1 0 ABC transporter Acyl_transf_2 PF02273.10 CEP19145.1 - 0.1 11.5 0.1 3.9 6.4 0.0 2.0 1 1 0 2 2 2 0 Acyl transferase BPL_LplA_LipB PF03099.14 CEP19147.1 - 1.3e-21 76.8 0.0 4.3e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 CEP19147.1 - 2e-07 30.5 0.5 9e-07 28.4 0.0 2.4 3 0 0 3 3 3 1 Bacterial lipoate protein ligase C-terminus CbiC PF02570.10 CEP19147.1 - 0.043 13.2 0.1 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Precorrin-8X methylmutase DUF1754 PF08555.5 CEP19148.1 - 1.5e-05 25.5 29.9 0.0016 18.9 9.3 2.7 2 1 1 3 3 3 2 Eukaryotic family of unknown function (DUF1754) DUF4618 PF15397.1 CEP19148.1 - 0.0074 15.6 12.4 0.0088 15.4 8.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) PRP1_N PF06424.7 CEP19148.1 - 0.054 13.8 10.2 0.076 13.3 7.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SPX PF03105.14 CEP19148.1 - 0.055 13.2 9.2 0.069 12.9 6.4 1.1 1 0 0 1 1 1 0 SPX domain RabGAP-TBC PF00566.13 CEP19148.1 - 0.058 12.8 3.6 0.067 12.6 2.5 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Alpha-E PF04168.7 CEP19148.1 - 0.12 11.6 2.9 0.17 11.2 2.0 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. IFT46_B_C PF12317.3 CEP19148.1 - 0.23 10.7 2.8 0.3 10.4 1.9 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal GvpL_GvpF PF06386.6 CEP19148.1 - 0.45 10.0 5.5 0.52 9.8 3.8 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Allexi_40kDa PF05549.6 CEP19148.1 - 0.46 9.7 3.2 0.51 9.5 2.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein IFT43 PF15305.1 CEP19148.1 - 0.48 10.4 6.7 0.58 10.1 4.7 1.1 1 0 0 1 1 1 0 Intraflagellar transport protein 43 DUF4191 PF13829.1 CEP19148.1 - 0.54 9.3 3.4 0.73 8.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4071 PF13281.1 CEP19148.1 - 0.6 8.8 6.8 0.66 8.7 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Peptidase_S46 PF10459.4 CEP19148.1 - 0.8 8.0 7.5 0.89 7.8 5.2 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF2265 PF10023.4 CEP19148.1 - 1.1 8.3 6.9 1.3 8.0 4.8 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Atrophin-1 PF03154.10 CEP19148.1 - 1.1 7.2 11.2 1.2 7.1 7.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Frigida PF07899.6 CEP19148.1 - 1.9 7.2 10.5 2.4 6.8 7.3 1.1 1 0 0 1 1 1 0 Frigida-like protein HemY_N PF07219.8 CEP19148.1 - 1.9 8.0 3.7 2.4 7.7 0.9 1.9 1 1 1 2 2 2 0 HemY protein N-terminus YlqD PF11068.3 CEP19148.1 - 2 8.4 15.8 2.5 8.1 10.9 1.1 1 0 0 1 1 1 0 YlqD protein APG6 PF04111.7 CEP19148.1 - 2.1 7.3 11.4 2.3 7.1 7.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 CEP19148.1 - 2.2 7.3 9.6 2.6 7.1 6.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ax_dynein_light PF10211.4 CEP19148.1 - 2.6 7.8 14.2 3.4 7.4 9.8 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain V_ATPase_I PF01496.14 CEP19148.1 - 2.6 5.7 10.2 3.1 5.5 7.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 CEP19148.1 - 2.7 7.5 15.7 3.4 7.2 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HSP70 PF00012.15 CEP19148.1 - 3.9 5.2 10.7 4.2 5.1 7.4 1.0 1 0 0 1 1 1 0 Hsp70 protein AAA_23 PF13476.1 CEP19148.1 - 3.9 7.7 11.2 5.9 7.1 7.8 1.3 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 CEP19148.1 - 4.1 7.2 10.0 8.3 6.2 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 CEP19148.1 - 4.9 7.2 10.3 7.9 6.5 7.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family VIT1 PF01988.14 CEP19148.1 - 5.1 6.5 6.0 6.2 6.2 4.2 1.2 1 0 0 1 1 1 0 VIT family PBP1_TM PF14812.1 CEP19148.1 - 5.3 7.4 11.9 7.9 6.8 8.1 1.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF342 PF03961.8 CEP19148.1 - 5.7 5.2 11.4 6.5 5.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMPIT PF07851.8 CEP19148.1 - 6.9 5.6 8.4 9 5.2 5.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein CAF1A PF12253.3 CEP19149.1 - 2.1e-23 82.2 3.6 2.1e-23 82.2 2.5 2.9 2 1 0 2 2 1 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 CEP19149.1 - 3.2e-09 36.4 45.1 6.5e-09 35.4 31.2 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal eIF3_subunit PF08597.5 CEP19149.1 - 0.0074 15.8 25.1 0.0074 15.8 17.4 2.1 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit Borrelia_P83 PF05262.6 CEP19149.1 - 0.075 11.2 24.5 0.12 10.5 17.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein SprA-related PF12118.3 CEP19149.1 - 0.1 11.9 19.8 0.18 11.0 13.8 1.4 1 0 0 1 1 1 0 SprA-related family Asp-B-Hydro_N PF05279.6 CEP19149.1 - 0.21 11.4 26.1 0.49 10.1 18.1 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region U79_P34 PF03064.11 CEP19149.1 - 0.28 10.6 23.6 0.54 9.7 16.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Mem_trans PF03547.13 CEP19149.1 - 0.55 8.4 4.5 0.85 7.8 3.1 1.3 1 0 0 1 1 1 0 Membrane transport protein LMBR1 PF04791.11 CEP19149.1 - 0.66 8.5 5.9 0.96 7.9 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1510 PF07423.6 CEP19149.1 - 0.88 8.8 30.6 1.9 7.8 21.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF913 PF06025.7 CEP19149.1 - 2.4 6.8 11.3 4.5 5.9 7.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.7 CEP19149.1 - 2.8 7.8 21.7 0.85 9.5 12.8 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family BSMAP PF12280.3 CEP19149.1 - 3.4 7.5 13.8 1.6 8.5 7.8 1.8 2 0 0 2 2 1 0 Brain specific membrane anchored protein Vfa1 PF08432.5 CEP19149.1 - 5.1 7.0 35.3 1.2 9.1 19.8 2.9 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.3 CEP19149.1 - 7.2 5.2 32.0 12 4.4 22.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 CEP19149.1 - 8.6 5.4 27.8 15 4.6 19.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.2 CEP19149.1 - 8.6 3.8 22.6 13 3.2 15.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 CEP19149.1 - 9.5 5.2 26.9 1 8.4 15.6 1.5 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein DUF3402 PF11882.3 CEP19150.1 - 8.6e-89 298.4 17.6 1e-88 298.1 7.8 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CEP19150.1 - 1.9e-30 105.7 1.5 1.9e-30 105.7 1.1 2.2 2 1 0 2 2 2 1 N1221-like protein Upf2 PF04050.9 CEP19150.1 - 0.013 15.2 9.3 0.039 13.7 6.4 1.8 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Sporozoite_P67 PF05642.6 CEP19150.1 - 7.1 4.3 4.6 11 3.7 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Abhydro_lipase PF04083.11 CEP19151.1 - 3.6e-17 61.4 0.2 1.4e-16 59.5 0.1 2.0 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 CEP19151.1 - 4.6e-16 59.0 0.2 6.9e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEP19151.1 - 3.5e-07 30.3 0.1 6.4e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP19151.1 - 5.8e-06 26.1 0.0 2.5e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 CEP19152.1 - 5e-56 184.7 19.0 1e-09 37.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CEP19152.1 - 3.1e-08 33.5 0.6 0.0028 17.4 0.0 3.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CEP19152.1 - 1.7e-05 24.4 0.3 4.3e-05 23.0 0.2 1.8 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 CEP19152.1 - 2.2e-05 22.9 0.3 0.028 12.7 0.0 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain BBS2_Mid PF14783.1 CEP19152.1 - 7.2e-05 22.5 0.1 1 9.1 0.0 4.5 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 CEP19152.1 - 0.00011 21.1 1.9 0.064 11.9 0.1 3.2 1 1 1 3 3 3 3 Nup133 N terminal like PQQ_3 PF13570.1 CEP19152.1 - 0.0048 17.1 3.5 0.13 12.5 0.2 3.9 4 1 0 4 4 4 1 PQQ-like domain DUF1900 PF08954.6 CEP19152.1 - 0.13 11.7 0.0 5.6 6.4 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1900) VCBS PF13517.1 CEP19152.1 - 0.41 11.0 3.6 4.8 7.6 2.0 2.8 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Aminotran_1_2 PF00155.16 CEP19153.1 - 4.7e-43 147.5 0.0 7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II ADH_zinc_N PF00107.21 CEP19153.1 - 0.00026 20.5 0.0 0.00059 19.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP19153.1 - 0.00027 20.6 0.1 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cys_Met_Meta_PP PF01053.15 CEP19153.1 - 0.0065 14.7 0.0 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CEP19153.1 - 0.0083 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Bundlin PF05307.6 CEP19153.1 - 0.052 13.4 0.3 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Bundlin Biotin_lipoyl PF00364.17 CEP19153.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme ADH_N PF08240.7 CEP19154.1 - 3e-26 91.3 8.0 5.7e-26 90.4 5.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEP19154.1 - 8.6e-17 60.9 0.0 1.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEP19154.1 - 0.00054 19.1 0.0 0.00089 18.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CEP19154.1 - 0.0033 17.0 0.1 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CEP19154.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_31 PF13847.1 CEP19154.1 - 0.02 14.4 0.0 0.087 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N_2 PF13602.1 CEP19154.1 - 0.04 14.8 0.0 0.065 14.1 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 CEP19154.1 - 0.099 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 CEP19154.1 - 0.18 12.3 0.4 5 7.7 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain NADH_4Fe-4S PF10589.4 CEP19154.1 - 1 8.5 7.4 1.3 8.2 4.2 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PAH PF02671.16 CEP19155.1 - 1.7e-44 149.1 7.5 1.7e-16 59.5 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CEP19155.1 - 1e-37 127.9 0.5 1e-37 127.9 0.3 2.4 2 0 0 2 2 2 1 Sin3 family co-repressor DUF1987 PF09345.5 CEP19155.1 - 0.16 11.7 3.9 2.3 8.0 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1987) Pyridox_oxase_2 PF12766.2 CEP19156.1 - 0.00014 22.1 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CMAS PF02353.15 CEP19157.1 - 2.8e-08 33.2 0.0 3.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CEP19157.1 - 2.7e-07 31.1 0.0 4.8e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP19157.1 - 1.9e-05 25.0 0.0 3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CEP19157.1 - 2e-05 25.3 0.0 3.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP19157.1 - 3.7e-05 23.3 0.1 0.00016 21.2 0.1 1.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP19157.1 - 0.012 14.6 0.1 0.042 12.9 0.0 1.7 2 1 0 2 2 2 0 Putative methyltransferase Methyltransf_12 PF08242.7 CEP19157.1 - 0.013 15.9 0.2 0.028 14.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 CEP19157.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain P35 PF02331.10 CEP19157.1 - 0.11 11.5 0.8 4.3 6.3 0.1 2.1 2 0 0 2 2 2 0 Apoptosis preventing protein cwf21 PF08312.7 CEP19157.1 - 0.18 11.6 3.1 0.33 10.8 2.2 1.3 1 0 0 1 1 1 0 cwf21 domain SH2_2 PF14633.1 CEP19158.1 - 4.3e-63 212.3 0.0 4.3e-63 212.3 0.0 2.3 3 0 0 3 3 3 1 SH2 domain YqgF PF14639.1 CEP19158.1 - 3.5e-32 111.0 0.1 1e-31 109.5 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 CEP19158.1 - 2.9e-31 107.9 1.2 2.9e-31 107.9 0.8 3.9 3 1 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 CEP19158.1 - 1.1e-26 92.9 0.0 2.5e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CEP19158.1 - 7.3e-18 64.7 3.1 9.2e-18 64.3 0.4 2.6 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 CEP19158.1 - 7.2e-15 54.9 36.6 7.2e-15 54.9 25.4 6.6 4 2 1 5 5 5 1 Acidic N-terminal SPT6 S1 PF00575.18 CEP19158.1 - 1.1e-06 28.5 0.1 3.5e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 CEP19158.1 - 2e-06 27.5 0.0 5.7e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 CEP19158.1 - 0.00098 19.0 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Macoilin PF09726.4 CEP19159.1 - 6.3 4.9 9.2 6.9 4.8 6.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 CEP19160.1 - 0.099 12.6 3.1 0.55 10.2 2.1 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region P12 PF12669.2 CEP19160.1 - 0.35 11.0 7.5 0.1 12.8 3.1 1.6 1 1 1 2 2 2 0 Virus attachment protein p12 family Extensin_2 PF04554.8 CEP19160.1 - 4 7.3 26.9 7.5 6.5 18.7 1.4 1 1 0 1 1 1 0 Extensin-like region DUF605 PF04652.11 CEP19160.1 - 9.1 5.5 11.5 10 5.3 8.0 1.0 1 0 0 1 1 1 0 Vta1 like Malate_synthase PF01274.17 CEP19163.1 - 1.3e-226 752.7 0.0 1.4e-226 752.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 CEP19163.1 - 0.023 13.5 0.0 0.051 12.4 0.0 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Peptidase_M48 PF01435.13 CEP19164.1 - 4.5e-55 186.6 0.0 6.7e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 CEP19164.1 - 3.1e-05 23.0 0.6 0.00034 19.6 0.5 2.3 3 0 0 3 3 3 1 BlaR1 peptidase M56 SprT-like PF10263.4 CEP19164.1 - 0.064 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 SprT-like family DUF955 PF06114.8 CEP19164.1 - 0.11 12.1 2.3 0.45 10.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF955) WD40 PF00400.27 CEP19165.1 - 3.1e-18 64.9 5.0 8.2e-06 25.5 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Ins_P5_2-kin PF06090.7 CEP19166.1 - 1.9e-62 211.1 0.9 2.2e-62 210.9 0.6 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Rota_NS53 PF00981.12 CEP19166.1 - 0.016 13.8 0.2 0.03 13.0 0.1 1.4 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) DUF4349 PF14257.1 CEP19166.1 - 0.042 13.0 0.3 0.062 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Ecl1 PF12855.2 CEP19167.1 - 9.5e-09 34.4 5.0 1.6e-08 33.6 3.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor PLATZ PF04640.9 CEP19167.1 - 0.56 10.4 4.9 0.91 9.7 3.4 1.3 1 0 0 1 1 1 0 PLATZ transcription factor zf-C2H2_jaz PF12171.3 CEP19167.1 - 5.5 7.2 6.3 1.9 8.7 1.7 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NAC PF01849.13 CEP19168.1 - 4.5e-22 77.3 0.0 1.4e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 NAC domain Peptidase_C48 PF02902.14 CEP19168.1 - 4.3e-11 42.8 1.7 2.6e-10 40.3 0.1 2.6 1 1 1 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Pyrophosphatase PF00719.14 CEP19170.1 - 1.7e-52 176.9 0.3 2.4e-52 176.5 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase G-alpha PF00503.15 CEP19171.1 - 6.9e-119 397.0 3.0 8.9e-119 396.6 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEP19171.1 - 5.4e-15 55.0 1.0 4.1e-10 39.1 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEP19171.1 - 0.0004 19.6 0.2 0.42 9.7 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP19171.1 - 0.0011 19.4 0.2 0.56 10.7 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein GTP_EFTU PF00009.22 CEP19171.1 - 0.02 14.3 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CEP19171.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1_like PF12832.2 CEP19172.1 - 1.3e-12 47.2 0.5 3.6e-12 45.8 0.0 2.0 2 1 1 3 3 3 1 MFS_1 like family Pro_isomerase PF00160.16 CEP19173.1 - 3.2e-47 160.6 0.9 3.8e-47 160.3 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ThiF PF00899.16 CEP19174.1 - 3.3e-52 175.8 0.0 7e-32 110.0 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CEP19174.1 - 2.1e-48 163.5 0.1 5e-48 162.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CEP19174.1 - 1.7e-41 139.6 2.3 4.8e-27 93.3 0.2 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CEP19174.1 - 6.4e-27 92.6 0.9 2.1e-22 78.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site E2_bind PF08825.5 CEP19174.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 E2 binding domain RE_Alw26IDE PF09665.5 CEP19174.1 - 0.1 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) SMP PF04927.7 CEP19175.1 - 0.0016 18.3 1.0 0.0029 17.5 0.7 1.5 1 0 0 1 1 1 1 Seed maturation protein Phasin_2 PF09361.5 CEP19175.1 - 0.06 13.3 1.6 0.13 12.3 1.1 1.6 1 1 0 1 1 1 0 Phasin protein DUF128 PF01995.11 CEP19175.1 - 0.14 11.0 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF128 Pkinase PF00069.20 CEP19177.1 - 3.2e-64 216.6 0.0 3.2e-64 216.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19177.1 - 1.5e-53 181.5 0.0 2.3e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19177.1 - 0.00012 21.1 0.0 0.016 14.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CEP19177.1 - 0.0006 19.2 0.4 0.0017 17.7 0.3 1.8 1 0 0 1 1 1 1 RIO1 family zf-RING_2 PF13639.1 CEP19177.1 - 0.0018 18.0 10.8 0.0041 16.9 7.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING-like PF08746.6 CEP19177.1 - 0.18 11.8 8.9 0.69 9.9 6.4 1.9 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 CEP19177.1 - 1 9.1 10.2 2.5 7.8 7.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 CEP19177.1 - 7.9 6.2 11.4 24 4.7 7.9 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Hemerythrin PF01814.18 CEP19179.1 - 4.4e-11 43.0 1.7 6.1e-11 42.6 1.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DNA_ligase_A_M PF01068.16 CEP19180.1 - 5e-40 137.0 2.1 9.9e-40 136.0 0.7 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CEP19180.1 - 6.6e-34 117.2 0.3 1.3e-33 116.2 0.2 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CEP19180.1 - 8.8e-08 32.4 0.0 5.1e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 CEP19180.1 - 4.8e-07 29.8 0.0 0.00038 20.5 0.0 3.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 CEP19180.1 - 6.4e-07 29.2 1.6 2.1e-05 24.3 1.1 2.9 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DSPc PF00782.15 CEP19181.1 - 3.1e-26 91.5 2.1 6e-19 67.9 0.5 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP19181.1 - 4.1e-06 26.3 0.1 7.9e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CEP19181.1 - 0.00032 20.7 0.1 0.00066 19.7 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 CEP19181.1 - 0.023 14.0 0.1 0.044 13.1 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family HABP4_PAI-RBP1 PF04774.10 CEP19182.1 - 0.00064 20.1 6.4 0.00064 20.1 4.4 3.7 3 2 0 3 3 3 1 Hyaluronan / mRNA binding family GerA PF03323.8 CEP19182.1 - 0.1 10.7 0.8 0.14 10.2 0.6 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Stm1_N PF09598.5 CEP19182.1 - 0.71 10.6 0.0 0.71 10.6 0.0 4.0 4 1 0 4 4 4 0 Stm1 Methyltransf_26 PF13659.1 CEP19183.1 - 1.6e-15 57.1 0.0 2.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP19183.1 - 3.2e-14 52.7 0.0 7.6e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP19183.1 - 4.2e-10 40.1 0.0 9.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP19183.1 - 6.4e-10 38.6 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CEP19183.1 - 1.3e-06 28.7 0.0 3.4e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PseudoU_synth_2 PF00849.17 CEP19183.1 - 2.8e-06 27.2 0.0 5.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase PrmA PF06325.8 CEP19183.1 - 5e-06 25.8 0.4 1.4e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 CEP19183.1 - 5.3e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.7 CEP19183.1 - 9.3e-06 24.9 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_25 PF13649.1 CEP19183.1 - 2.3e-05 24.6 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP19183.1 - 0.0018 18.7 0.0 0.0046 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CEP19183.1 - 0.012 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 CEP19183.1 - 0.053 12.8 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 CEP19183.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Whi5 PF08528.6 CEP19184.1 - 7.5e-05 22.2 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Whi5 like Ilar_coat PF01787.11 CEP19185.1 - 0.081 12.4 0.1 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein FAM165 PF14981.1 CEP19185.1 - 0.12 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 FAM165 family DUF1206 PF06724.6 CEP19185.1 - 0.13 12.0 3.8 0.34 10.7 0.8 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) YtpI PF14007.1 CEP19185.1 - 0.27 11.2 5.4 4.4 7.2 0.8 3.0 1 1 2 3 3 3 0 YtpI-like protein DUF202 PF02656.10 CEP19185.1 - 1 9.6 5.9 21 5.4 0.1 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF202) NTF2 PF02136.15 CEP19186.1 - 1.7e-27 96.1 0.1 2.3e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Thioredoxin PF00085.15 CEP19187.1 - 3.9e-63 209.6 0.0 1e-31 108.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 CEP19187.1 - 1.3e-19 70.6 0.5 2.9e-19 69.5 0.3 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.1 CEP19187.1 - 4.8e-14 52.1 0.0 1e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CEP19187.1 - 1.7e-12 47.5 0.4 4.6e-05 23.5 0.1 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEP19187.1 - 1.4e-10 41.1 0.1 0.00087 19.3 0.0 3.3 3 2 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CEP19187.1 - 1.6e-07 31.0 0.1 0.021 14.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CEP19187.1 - 1.6e-05 24.4 0.1 0.038 13.5 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 CEP19187.1 - 0.028 13.9 0.2 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 CEP19187.1 - 0.074 13.0 0.2 30 4.5 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin HyaE PF07449.6 CEP19187.1 - 0.16 11.8 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE LPAM_1 PF08139.7 CEP19187.1 - 2.1 8.6 4.0 4 7.8 2.8 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Pyridoxal_deC PF00282.14 CEP19188.1 - 1.3e-82 277.2 0.0 2.1e-82 276.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain RasGEF PF00617.14 CEP19188.1 - 3.1e-62 209.6 0.3 6.1e-62 208.7 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEP19188.1 - 5e-28 97.2 1.6 1.2e-27 95.9 0.3 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 CEP19188.1 - 5.7e-14 51.2 0.4 1.5e-13 49.8 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP19188.1 - 1.8e-11 43.3 0.4 4.2e-11 42.2 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEP19188.1 - 3.3e-11 42.5 0.0 7.6e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 CEP19188.1 - 1.1e-06 28.4 2.0 0.0041 16.9 0.1 3.1 3 0 0 3 3 3 2 WW domain Aminotran_5 PF00266.14 CEP19188.1 - 9.6e-05 21.2 0.0 0.00027 19.8 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CEP19188.1 - 0.00024 20.3 0.0 0.00044 19.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase UAA PF08449.6 CEP19188.1 - 0.17 10.7 0.2 17 4.1 0.0 2.3 2 0 0 2 2 2 0 UAA transporter family HAD_2 PF13419.1 CEP19189.1 - 1.1e-15 58.3 0.0 1.7e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP19189.1 - 8e-05 23.1 0.0 0.00026 21.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP19189.1 - 0.0017 18.0 0.2 0.0059 16.2 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like TFIIE-A_C-term PF11521.3 CEP19190.1 - 0.022 14.6 1.7 0.048 13.6 0.2 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha zf-H2C2_2 PF13465.1 CEP19191.1 - 4.5e-07 29.8 2.8 4.5e-07 29.8 1.9 3.7 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEP19191.1 - 5.9e-05 23.1 1.0 5.9e-05 23.1 0.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP19191.1 - 0.017 15.3 0.5 0.017 15.3 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Clp1 PF06807.9 CEP19192.1 - 1.5e-10 41.1 0.0 4.2e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CEP19192.1 - 3.1e-10 39.8 0.0 1e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TCO89 PF10452.4 CEP19193.1 - 5.6e-08 32.1 7.3 5.6e-08 32.1 5.1 2.6 1 1 0 2 2 2 1 TORC1 subunit TCO89 HJURP_C PF12347.3 CEP19193.1 - 0.015 14.8 0.1 0.059 12.9 0.1 2.1 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat tRNA_bind_2 PF13725.1 CEP19193.1 - 0.036 14.1 0.5 0.67 10.0 0.0 2.5 2 0 0 2 2 2 0 Possible tRNA binding domain DDE_3 PF13358.1 CEP19195.1 - 0.001 18.7 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2615 PF11027.3 CEP19196.1 - 0.0015 18.4 0.8 0.0017 18.2 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2615) LMBR1 PF04791.11 CEP19197.1 - 1e-50 172.6 19.2 1.8e-50 171.9 13.3 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein ADH_zinc_N PF00107.21 CEP19198.1 - 1.1e-14 54.1 0.0 2.5e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP19198.1 - 3.4e-13 50.6 0.0 1e-12 49.0 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP19198.1 - 1.1e-12 47.6 0.2 2e-11 43.6 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.3 CEP19198.1 - 0.00075 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Semialdhyde_dh PF01118.19 CEP19198.1 - 0.0063 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 CEP19198.1 - 0.0094 15.4 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CEP19198.1 - 0.032 14.0 0.6 0.062 13.0 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DXP_reductoisom PF02670.11 CEP19198.1 - 0.05 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF2781 PF10914.3 CEP19199.1 - 1.4e-38 132.0 12.5 1.6e-38 131.7 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) His_Phos_1 PF00300.17 CEP19200.1 - 1.1e-31 110.0 0.4 1.6e-31 109.5 0.0 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) GCV_T PF01571.16 CEP19201.1 - 4.1e-69 232.1 0.5 2e-68 229.8 0.0 2.0 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain RabGAP-TBC PF00566.13 CEP19201.1 - 7.1e-57 192.3 0.4 7.1e-57 192.3 0.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GCV_T_C PF08669.6 CEP19201.1 - 2.5e-25 88.3 0.4 5.4e-25 87.2 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CEP19201.1 - 0.00081 19.2 0.1 0.18 11.6 0.0 2.5 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family Methyltransf_33 PF10017.4 CEP19201.1 - 0.02 14.7 0.3 0.057 13.3 0.2 1.7 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Cep57_CLD_2 PF14197.1 CEP19201.1 - 0.084 12.8 16.9 0.018 14.9 6.8 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 MFS_1 PF07690.11 CEP19202.1 - 7.6e-41 139.9 29.3 7.6e-41 139.9 20.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CEP19202.1 - 0.5 10.1 9.3 0.34 10.7 0.1 3.3 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 CEP19202.1 - 0.68 7.9 10.0 0.026 12.6 1.9 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector HsbA PF12296.3 CEP19203.1 - 9.5e-12 44.8 1.2 9.5e-12 44.8 0.8 1.7 2 0 0 2 2 2 1 Hydrophobic surface binding protein A U3snoRNP10 PF12397.3 CEP19203.1 - 0.12 12.3 3.3 1.6 8.7 0.9 2.6 1 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Sdh5 PF03937.11 CEP19204.1 - 2.5e-25 87.9 0.3 3.5e-25 87.4 0.2 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase PRA-CH PF01502.13 CEP19204.1 - 0.097 12.3 0.2 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase Pkinase PF00069.20 CEP19205.1 - 4.7e-54 183.2 0.0 5.7e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19205.1 - 5.2e-23 81.4 0.0 6.7e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19205.1 - 0.0037 16.2 0.1 0.029 13.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CEP19205.1 - 0.13 11.9 0.1 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arf PF00025.16 CEP19206.1 - 7.6e-77 256.4 0.1 8.6e-77 256.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CEP19206.1 - 3.3e-14 52.5 0.0 3.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CEP19206.1 - 2.2e-12 46.5 0.0 2.6e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEP19206.1 - 3.6e-11 42.6 0.0 4.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CEP19206.1 - 5.9e-11 41.6 2.9 2.7e-07 29.6 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CEP19206.1 - 1.1e-07 32.3 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEP19206.1 - 2.8e-05 24.0 0.1 7e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP19206.1 - 0.00035 20.0 0.0 0.0024 17.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 CEP19206.1 - 0.003 16.6 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase DUF3986 PF13143.1 CEP19206.1 - 0.069 13.6 0.4 0.48 10.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3986) L27 PF02828.11 CEP19206.1 - 0.081 12.6 0.4 0.65 9.7 0.1 2.1 2 0 0 2 2 2 0 L27 domain P5CR_dimer PF14748.1 CEP19207.1 - 2.6e-38 130.2 1.7 5.1e-38 129.3 1.2 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CEP19207.1 - 1.5e-16 60.5 0.7 3.6e-16 59.3 0.0 2.0 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CEP19207.1 - 2.7e-07 30.4 1.2 2e-06 27.6 0.4 2.5 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OCD_Mu_crystall PF02423.10 CEP19207.1 - 0.0011 17.8 0.0 0.0026 16.5 0.0 1.6 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_2 PF03446.10 CEP19207.1 - 0.0067 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.4 CEP19207.1 - 0.008 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.11 CEP19207.1 - 0.033 13.6 0.6 0.13 11.6 0.4 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.13 CEP19208.1 - 0.0016 18.3 16.0 0.0027 17.5 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TP1 PF02079.11 CEP19208.1 - 4.1 7.2 9.4 1.8 8.3 2.5 2.3 2 0 0 2 2 2 0 Nuclear transition protein 1 DUF3543 PF12063.3 CEP19209.1 - 8.7e-48 162.6 6.9 3.1e-46 157.5 4.8 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 CEP19209.1 - 6e-44 150.1 0.0 1.1e-43 149.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19209.1 - 8.3e-24 84.0 0.0 1.3e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP19209.1 - 0.00097 18.9 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP19209.1 - 0.01 14.7 0.1 0.11 11.4 0.1 2.2 1 1 0 1 1 1 0 Kinase-like MRI PF15325.1 CEP19209.1 - 0.059 14.3 0.5 0.059 14.3 0.4 2.9 2 1 1 3 3 3 0 Modulator of retrovirus infection RRM_1 PF00076.17 CEP19210.1 - 1.1e-19 69.8 0.0 2.2e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP19210.1 - 6.6e-14 51.6 0.0 1.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP19210.1 - 6.6e-06 25.8 0.1 1.2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CEP19210.1 - 0.00064 19.3 0.0 0.00064 19.3 0.0 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain DUF2666 PF10869.3 CEP19210.1 - 0.25 11.3 1.8 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Mannosyl_trans3 PF11051.3 CEP19211.1 - 8.7e-45 153.1 0.2 8.6e-44 149.9 0.1 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Mating_N PF12731.2 CEP19211.1 - 0.16 11.8 0.1 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 Cmc1 PF08583.5 CEP19212.1 - 1.4e-15 56.8 4.6 1.7e-15 56.5 3.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CEP19212.1 - 0.23 11.5 5.7 1.6 8.7 0.5 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF2031 PF09592.5 CEP19214.1 - 0.028 13.5 1.0 0.036 13.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) CytochromB561_N PF09786.4 CEP19215.1 - 3.3e-05 22.5 0.0 4.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome B561, N terminal LtrA PF06772.6 CEP19216.1 - 5.9e-27 94.5 16.9 5.9e-27 94.5 11.7 2.7 2 1 1 3 3 3 1 Bacterial low temperature requirement A protein (LtrA) Mito_carr PF00153.22 CEP19217.1 - 5.3e-68 224.7 1.2 6e-24 83.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fe-S_biosyn PF01521.15 CEP19218.1 - 3.8e-17 62.2 0.1 5.2e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis zf-CCHC PF00098.18 CEP19219.1 - 2.7e-06 27.0 1.4 4.2e-06 26.4 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CEP19219.1 - 0.062 13.0 0.2 0.086 12.5 0.2 1.2 1 0 0 1 1 1 0 Zinc knuckle Shadoo PF14999.1 CEP19219.1 - 0.36 10.6 10.2 0.66 9.8 7.0 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective adh_short PF00106.20 CEP19220.1 - 6e-61 205.2 14.4 2.5e-31 108.8 2.3 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 CEP19220.1 - 8.7e-31 105.8 0.0 2.3e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 CEP19220.1 - 1.9e-29 102.5 9.2 1.2e-16 60.9 1.0 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.1 CEP19220.1 - 6.2e-13 48.6 0.0 1.9e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 CEP19220.1 - 4.8e-05 22.4 2.1 0.18 10.9 0.3 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1659 PF07872.6 CEP19220.1 - 0.051 13.1 0.0 0.56 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) DUF4161 PF13722.1 CEP19220.1 - 0.064 13.5 1.1 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) DAO PF01266.19 CEP19220.1 - 0.16 10.8 5.2 0.7 8.7 0.1 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 CEP19220.1 - 0.76 9.4 7.9 5.2 6.6 0.7 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HAD_2 PF13419.1 CEP19221.1 - 1.1e-18 68.0 0.0 1.5e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP19221.1 - 2.2e-12 46.5 0.0 3.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CEP19221.1 - 1.5e-10 41.8 2.3 1.1e-08 35.7 0.4 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP19221.1 - 0.0058 16.8 0.2 0.0086 16.2 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CENP-H PF05837.7 CEP19222.1 - 0.054 13.6 0.6 0.077 13.1 0.4 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Swi5 PF07061.6 CEP19222.1 - 0.13 12.0 1.6 0.18 11.6 1.1 1.3 1 1 0 1 1 1 0 Swi5 zf-C2H2 PF00096.21 CEP19223.1 - 8.4e-15 54.1 21.1 1.5e-06 28.2 2.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP19223.1 - 9.1e-12 44.6 13.9 7.7e-07 29.0 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP19223.1 - 1e-10 41.1 18.9 0.00045 20.3 1.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP19223.1 - 0.00036 20.5 9.0 1.3 9.2 0.1 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CEP19223.1 - 0.0079 15.9 5.0 0.35 10.6 0.4 2.9 2 1 0 2 2 2 2 BED zinc finger Zn_Tnp_IS1595 PF12760.2 CEP19223.1 - 0.22 11.3 7.3 1.1 9.0 1.4 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-met PF12874.2 CEP19223.1 - 0.25 11.5 5.8 3.8 7.8 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CEP19223.1 - 1.1 9.2 6.9 6.3 6.8 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 CEP19223.1 - 4.5 7.4 11.2 68 3.6 7.0 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) LIM PF00412.17 CEP19223.1 - 6.1 6.9 8.8 0.84 9.7 2.5 2.4 2 0 0 2 2 2 0 LIM domain DUF566 PF04484.7 CEP19224.1 - 0.0015 18.1 0.3 0.0019 17.7 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF566) SET PF00856.23 CEP19225.1 - 1.3e-07 32.0 0.0 1.4e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 SET domain SAF PF08666.7 CEP19225.1 - 0.085 13.2 0.0 4.4 7.7 0.0 2.3 2 0 0 2 2 2 0 SAF domain SH3_1 PF00018.23 CEP19226.1 - 1.4e-15 56.4 0.1 2.1e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP19226.1 - 1.2e-14 53.5 0.0 2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CEP19226.1 - 2e-14 52.8 0.0 3.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PPP5 PF08321.7 CEP19227.1 - 0.0067 16.4 0.2 0.028 14.4 0.1 2.1 1 0 0 1 1 1 1 PPP5 TPR repeat region Isochorismatase PF00857.15 CEP19228.1 - 3.8e-23 82.3 0.0 6.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family HMG_box PF00505.14 CEP19233.1 - 8.6e-16 57.9 1.6 8.6e-16 57.9 1.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.25 CEP19233.1 - 6.2e-13 48.7 0.6 1.1e-12 47.8 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 CEP19233.1 - 3.8e-11 43.2 1.4 3.8e-11 43.2 1.0 2.3 1 1 1 2 2 2 1 HMG-box domain SAM_2 PF07647.12 CEP19233.1 - 7e-09 35.4 0.1 7e-09 35.4 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 CEP19233.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) CLU PF13236.1 CEP19234.1 - 5.1e-86 287.6 0.7 2.4e-85 285.4 0.0 2.2 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 CEP19234.1 - 4.7e-45 153.5 1.6 7.9e-45 152.8 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 CEP19234.1 - 6.1e-23 80.7 0.1 2.1e-22 79.0 0.0 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 CEP19234.1 - 3.9e-21 74.7 2.8 9.5e-08 31.8 0.0 3.5 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 CEP19234.1 - 2e-16 59.2 0.8 3.2e-06 26.8 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF727 PF05303.7 CEP19234.1 - 8.6e-06 25.5 0.2 3.4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_11 PF13414.1 CEP19234.1 - 0.00025 20.6 0.5 1.2 8.8 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 CEP19234.1 - 0.1 12.5 6.6 20 5.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP19234.1 - 0.17 11.7 2.1 29 4.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GST_C PF00043.20 CEP19235.1 - 2.8e-08 33.6 0.0 4.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP19235.1 - 3.9e-07 30.4 0.0 1.4e-06 28.7 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEP19235.1 - 4.5e-06 26.4 0.0 1.8e-05 24.5 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CEP19235.1 - 0.00062 19.9 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP19235.1 - 0.0016 18.5 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CEP19235.1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin bZIP_2 PF07716.10 CEP19237.1 - 5.6e-07 29.2 14.2 5.6e-07 29.2 9.8 2.2 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 CEP19237.1 - 4.2e-06 26.6 14.4 5e-06 26.3 9.2 1.8 1 1 1 2 2 2 2 bZIP transcription factor Spc42p PF11544.3 CEP19237.1 - 0.0067 16.3 0.8 0.0067 16.3 0.6 2.9 2 1 0 2 2 2 1 Spindle pole body component Spc42p bZIP_Maf PF03131.12 CEP19237.1 - 0.0094 16.2 11.3 0.0094 16.2 7.9 2.8 2 1 1 3 3 3 1 bZIP Maf transcription factor DivIC PF04977.10 CEP19237.1 - 0.017 14.6 1.6 0.017 14.6 1.1 3.1 3 1 1 4 4 4 0 Septum formation initiator DUF2400 PF09674.5 CEP19237.1 - 0.17 11.5 2.7 0.27 10.8 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) DUF972 PF06156.8 CEP19237.1 - 0.48 10.7 5.2 1.1 9.6 3.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) CCDC-167 PF15188.1 CEP19237.1 - 5.4 7.0 7.3 7.5 6.5 4.6 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 PSCyt3 PF07627.6 CEP19237.1 - 5.4 6.9 7.8 3.2 7.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) DUF904 PF06005.7 CEP19237.1 - 5.5 7.3 18.2 12 6.3 0.2 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Sec7_N PF12783.2 CEP19238.1 - 3.5e-33 114.4 4.1 3.5e-33 114.4 2.9 4.1 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CEP19238.1 - 0.0012 18.2 1.2 0.034 13.6 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DUF4519 PF15012.1 CEP19238.1 - 0.19 11.7 0.2 0.57 10.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DHODB_Fe-S_bind PF10418.4 CEP19239.1 - 0.004 16.6 0.6 0.01 15.2 0.4 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B OST-HTH PF12872.2 CEP19239.1 - 0.039 13.8 0.3 0.12 12.2 0.2 1.8 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Gti1_Pac2 PF09729.4 CEP19240.1 - 1.6e-54 184.3 0.0 1.6e-54 184.3 0.0 2.9 2 1 0 2 2 2 1 Gti1/Pac2 family WD40 PF00400.27 CEP19241.1 - 1.2e-53 177.1 19.6 6.6e-09 35.3 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 CEP19241.1 - 5.5e-09 35.6 0.4 1e-08 34.7 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CEP19241.1 - 1.9e-06 26.3 9.2 0.018 13.1 0.1 5.4 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CEP19241.1 - 1.2e-05 24.8 2.0 0.051 13.0 0.2 3.2 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.1 CEP19241.1 - 0.00019 21.6 1.0 1.2e+02 3.1 0.0 6.2 5 1 1 6 6 6 0 PQQ-like domain F-box PF00646.28 CEP19241.1 - 0.0073 15.9 0.2 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain Sulfate_transp PF00916.15 CEP19242.1 - 7.3e-64 215.4 11.1 7.3e-64 215.4 7.7 1.6 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEP19242.1 - 1.3e-26 92.0 3.8 6.1e-26 89.9 2.7 2.3 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEP19242.1 - 7.8e-22 76.9 0.0 1.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CEP19242.1 - 0.00093 19.1 0.1 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 STAS domain DUF2254 PF10011.4 CEP19242.1 - 0.022 13.2 1.3 0.046 12.1 0.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Methyltransf_16 PF10294.4 CEP19243.1 - 3.7e-37 127.4 0.1 4.6e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CEP19243.1 - 3.7e-05 23.1 0.0 5.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CEP19243.1 - 0.00011 21.8 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP19243.1 - 0.00034 21.1 0.0 0.00043 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CEP19243.1 - 0.00062 18.9 0.0 0.00067 18.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 CEP19243.1 - 0.025 13.7 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Met_10 PF02475.11 CEP19243.1 - 0.042 13.4 0.0 0.057 13.0 0.0 1.3 1 1 0 1 1 1 0 Met-10+ like-protein RrnaAD PF00398.15 CEP19243.1 - 0.067 12.2 0.1 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 CEP19243.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain OrfB_Zn_ribbon PF07282.6 CEP19244.1 - 0.00011 21.7 0.0 0.0003 20.3 0.0 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain ATP-synt_F PF01990.12 CEP19245.1 - 1.3e-32 112.0 0.3 1.5e-32 111.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 CEP19245.1 - 0.044 12.7 0.1 0.062 12.2 0.1 1.3 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Eapp_C PF10238.4 CEP19246.1 - 8.1e-23 80.8 7.4 1.6e-22 79.8 3.2 2.2 1 1 1 2 2 2 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 CEP19246.1 - 0.0059 16.6 4.0 0.01 15.8 2.8 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly IBR PF01485.16 CEP19246.1 - 1.9 8.4 7.0 0.45 10.4 2.0 2.0 1 1 1 2 2 2 0 IBR domain DUF2296 PF10058.4 CEP19246.1 - 4 7.2 7.9 0.91 9.3 0.2 2.9 1 1 2 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Sec23_trunk PF04811.10 CEP19247.1 - 7.6e-60 202.2 0.0 1.3e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CEP19247.1 - 1.7e-20 73.2 0.0 4.4e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CEP19247.1 - 7.1e-16 57.5 0.5 1.4e-15 56.5 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CEP19247.1 - 1.4e-13 50.1 3.9 1.4e-13 50.1 2.7 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CEP19247.1 - 0.00053 19.6 0.0 0.00053 19.6 0.0 2.7 4 0 0 4 4 4 1 Gelsolin repeat VWA_2 PF13519.1 CEP19247.1 - 0.00067 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 CEP19248.1 - 3.4e-05 23.4 7.4 3.4e-05 23.4 5.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Not1 PF04054.10 CEP19249.1 - 9.7e-70 235.3 14.2 1.5e-69 234.7 9.9 1.2 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 FANCI_S2 PF14676.1 CEP19249.1 - 0.001 18.9 9.5 0.019 14.8 0.1 4.5 3 2 1 5 5 5 2 FANCI solenoid 2 Ras PF00071.17 CEP19250.1 - 1e-60 203.8 0.6 1.2e-60 203.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP19250.1 - 9.7e-21 74.4 0.1 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP19250.1 - 3.8e-14 52.3 0.1 5e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEP19250.1 - 4.8e-06 26.5 0.1 7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP19250.1 - 9e-06 25.2 0.1 1.8e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP19250.1 - 1.6e-05 24.1 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 CEP19250.1 - 1.7e-05 24.1 0.2 1.9e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CEP19250.1 - 0.0029 16.8 0.1 0.0056 15.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEP19250.1 - 0.0047 17.0 0.1 0.021 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 CEP19250.1 - 0.0088 15.0 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain SRPRB PF09439.5 CEP19250.1 - 0.014 14.6 0.1 0.026 13.7 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CEP19250.1 - 0.022 14.6 0.1 0.077 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CEP19250.1 - 0.026 14.2 0.1 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 CEP19250.1 - 0.027 14.7 0.5 0.057 13.7 0.4 1.8 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 CEP19250.1 - 0.093 11.7 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_5 PF07728.9 CEP19250.1 - 0.13 11.9 0.1 0.6 9.8 0.0 2.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEP19250.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.8 1 1 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 CEP19251.1 - 1.6e-51 174.9 0.0 2.5e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19251.1 - 6.9e-35 120.3 0.0 1e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19251.1 - 2.5e-09 36.5 0.0 4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FAD_binding_3 PF01494.14 CEP19252.1 - 2e-61 208.0 0.5 1.4e-60 205.2 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEP19252.1 - 2.5e-05 23.3 0.0 4.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CEP19252.1 - 0.0046 15.4 0.1 0.043 12.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CEP19252.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CEP19252.1 - 0.014 14.2 0.0 0.033 12.9 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.22 CEP19252.1 - 0.016 15.6 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEP19252.1 - 0.017 14.2 0.0 0.038 13.0 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 CEP19252.1 - 0.035 14.1 0.1 0.082 12.9 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP19252.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CEP19252.1 - 0.1 11.6 0.2 0.19 10.7 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 CEP19252.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LRR_6 PF13516.1 CEP19253.1 - 1.2e-16 58.8 14.6 0.023 14.7 0.1 8.7 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 CEP19253.1 - 5.6e-15 54.5 8.8 0.019 14.5 0.0 5.6 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CEP19253.1 - 4.5e-09 35.8 0.0 1.6e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 CEP19253.1 - 2.4e-08 33.6 12.3 0.13 12.0 0.0 4.8 4 1 0 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CEP19253.1 - 6.7e-06 25.4 18.9 1.2 9.4 0.1 7.8 8 1 0 8 8 8 3 Leucine Rich Repeat F-box PF00646.28 CEP19253.1 - 0.0011 18.5 0.0 0.0011 18.5 0.0 3.8 5 0 0 5 5 5 1 F-box domain LRR_7 PF13504.1 CEP19253.1 - 0.0092 16.0 23.9 1.1 9.7 0.2 8.5 8 1 1 9 9 9 2 Leucine rich repeat MFS_1 PF07690.11 CEP19254.1 - 4.6e-30 104.5 25.3 7e-30 103.9 17.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_23 PF13489.1 CEP19255.1 - 2.4e-07 30.6 0.0 6.8e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP19255.1 - 4e-05 24.0 0.0 0.013 15.9 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CEP19255.1 - 0.00036 21.0 0.0 0.11 13.1 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CEP19255.1 - 0.14 12.6 0.0 0.96 9.9 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain PIP5K PF01504.13 CEP19256.1 - 0.04 13.0 0.1 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DDE_3 PF13358.1 CEP19257.1 - 4.2e-18 65.5 0.0 5.2e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 CEP19257.1 - 0.087 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain UCH PF00443.24 CEP19258.1 - 3.9e-51 173.7 0.0 5.3e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP19258.1 - 1.8e-12 47.3 0.0 1.3e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SBDS_C PF09377.5 CEP19259.1 - 1.6e-42 144.1 1.4 2.8e-42 143.3 1.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 CEP19259.1 - 1.3e-32 111.4 1.6 2.3e-32 110.6 1.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HTH_22 PF13309.1 CEP19259.1 - 0.016 14.9 0.1 0.047 13.4 0.1 1.8 1 0 0 1 1 1 0 HTH domain DUF1092 PF06485.6 CEP19259.1 - 0.018 13.9 0.6 0.029 13.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1092) 2-Hacid_dh_C PF02826.14 CEP19259.1 - 0.028 13.5 0.3 0.24 10.5 0.1 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THDPS_N_2 PF14805.1 CEP19259.1 - 0.094 12.5 0.3 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Mon1 PF03164.9 CEP19260.1 - 1.9e-89 300.1 8.8 2.8e-85 286.4 1.8 2.4 2 1 1 3 3 3 2 Trafficking protein Mon1 NMT1 PF09084.6 CEP19261.1 - 6.3e-10 39.0 0.0 1.4e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 CEP19261.1 - 2.1e-09 37.1 0.1 5.3e-07 29.2 0.0 2.6 2 1 1 3 3 3 2 NMT1-like family Phosphonate-bd PF12974.2 CEP19261.1 - 3.5e-05 23.3 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.15 CEP19261.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DDHD PF02862.12 CEP19262.1 - 5.7e-21 75.3 23.0 3.9e-19 69.3 11.9 3.6 1 1 1 2 2 2 1 DDHD domain HMG_box PF00505.14 CEP19263.1 - 4.6e-20 71.6 7.8 5.7e-11 42.5 0.5 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP19263.1 - 3.7e-18 65.6 9.1 4.2e-11 43.0 0.6 2.9 2 1 0 2 2 2 2 HMG-box domain Imm35 PF15581.1 CEP19263.1 - 0.043 13.8 0.6 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 35 DUF1289 PF06945.8 CEP19263.1 - 0.1 12.0 6.3 3.5 7.1 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) Pkinase PF00069.20 CEP19264.1 - 5.6e-31 107.6 0.0 1.3e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.1 CEP19264.1 - 1.7e-16 59.8 32.0 1.1e-06 28.6 0.3 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CEP19264.1 - 2.8e-15 55.8 11.7 5.9e-05 22.9 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CEP19264.1 - 3e-14 52.4 19.4 7.5e-05 22.7 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 CEP19264.1 - 4.2e-13 48.8 13.2 6.2e-06 25.8 0.1 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 CEP19264.1 - 2.6e-12 46.0 17.3 0.025 14.1 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 CEP19264.1 - 4e-10 39.0 13.8 0.00025 20.6 0.1 6.8 6 0 0 6 6 6 3 Kelch motif Pkinase_Tyr PF07714.12 CEP19264.1 - 1.5e-07 30.7 0.0 7.5e-07 28.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19264.1 - 3.9e-05 22.7 0.0 6.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like EphA2_TM PF14575.1 CEP19264.1 - 0.41 11.0 5.4 0.55 10.6 0.0 3.4 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain CS PF04969.11 CEP19265.1 - 6.3e-19 68.3 0.1 1.1e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 CS domain adh_short_C2 PF13561.1 CEP19266.1 - 2.1e-30 106.2 0.2 2.7e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEP19266.1 - 4.5e-27 95.0 0.2 6.8e-27 94.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEP19266.1 - 8.4e-14 51.6 0.1 1.7e-13 50.6 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CEP19266.1 - 0.00033 20.1 0.3 0.00053 19.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEP19266.1 - 0.0021 16.7 0.5 0.0028 16.4 0.3 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_1 PF00232.13 CEP19266.1 - 0.0043 15.3 0.0 0.0058 14.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 F420_oxidored PF03807.12 CEP19266.1 - 0.012 16.0 0.3 0.12 12.8 0.1 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 CEP19266.1 - 0.091 11.6 0.4 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PX PF00787.19 CEP19268.1 - 5.7e-23 80.8 0.9 1.9e-22 79.1 0.2 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CEP19268.1 - 1.5e-20 73.4 11.5 4e-13 49.1 2.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 CEP19268.1 - 0.056 12.9 14.9 0.45 9.9 10.3 2.1 1 1 0 1 1 1 0 BAR domain TBPIP PF07106.8 CEP19268.1 - 0.066 12.7 9.2 0.046 13.2 1.8 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 CEP19268.1 - 0.078 13.4 0.9 18 5.8 0.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Baculo_PEP_C PF04513.7 CEP19268.1 - 0.089 12.6 4.5 0.074 12.8 1.6 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40_alt PF14077.1 CEP19268.1 - 0.16 11.6 1.9 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif BLOC1_2 PF10046.4 CEP19268.1 - 0.42 10.7 8.5 0.54 10.4 0.4 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 CEP19268.1 - 0.68 10.0 6.6 0.68 10.0 1.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 CEP19268.1 - 1 8.9 4.2 0.46 10.1 0.4 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 GrpE PF01025.14 CEP19268.1 - 1.2 8.7 12.9 0.066 12.7 0.6 2.8 2 1 0 2 2 2 0 GrpE DUF342 PF03961.8 CEP19268.1 - 2.9 6.2 7.4 0.5 8.7 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 CEP19268.1 - 4.1 6.3 12.4 0.5 9.3 3.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 CEP19268.1 - 9.1 5.8 9.5 2.5 7.6 1.7 2.5 2 1 0 2 2 2 0 IncA protein HTH_23 PF13384.1 CEP19269.1 - 0.00032 20.2 0.0 0.00086 18.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP19269.1 - 0.003 17.7 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_IclR PF09339.5 CEP19269.1 - 0.0051 16.3 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_32 PF13565.1 CEP19269.1 - 0.026 15.2 0.0 0.053 14.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 CEP19269.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_17 PF12728.2 CEP19269.1 - 0.04 14.1 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.1 CEP19269.1 - 0.11 12.5 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain NDUFA12 PF05071.11 CEP19270.1 - 5.2e-25 87.9 1.2 6.2e-25 87.6 0.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WD40 PF00400.27 CEP19271.1 - 7.1e-44 146.1 3.5 1.4e-09 37.4 0.0 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat FA_desaturase PF00487.19 CEP19271.1 - 1.7e-29 103.0 11.3 2.8e-29 102.3 7.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CEP19271.1 - 3.8e-08 32.4 0.2 7.4e-08 31.4 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Cytochrom_D1 PF02239.11 CEP19271.1 - 8.8e-05 20.9 0.1 0.058 11.6 0.0 3.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.3 CEP19271.1 - 0.00057 18.1 0.4 0.015 13.4 0.1 2.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CEP19271.1 - 0.021 14.2 0.0 0.086 12.2 0.0 1.8 1 1 1 2 2 2 0 PQQ-like domain BBS2_Mid PF14783.1 CEP19271.1 - 0.045 13.5 0.0 0.54 10.0 0.0 2.7 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region FH2 PF02181.18 CEP19272.1 - 1.8e-77 260.7 9.4 1.8e-77 260.7 6.5 2.7 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.8 CEP19272.1 - 8.6e-33 113.2 11.5 2.2e-28 98.9 0.0 4.4 4 0 0 4 4 4 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CEP19272.1 - 9.5e-22 77.3 0.1 9.5e-22 77.3 0.1 3.0 3 0 0 3 3 3 1 Diaphanous FH3 Domain HALZ PF02183.13 CEP19272.1 - 0.00023 20.8 9.1 0.00065 19.3 0.2 3.1 3 0 0 3 3 3 2 Homeobox associated leucine zipper NanE PF04131.9 CEP19272.1 - 0.002 17.1 0.1 0.0056 15.6 0.0 1.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IncA PF04156.9 CEP19272.1 - 0.0021 17.6 1.8 0.0021 17.6 1.3 4.1 3 1 0 3 3 3 1 IncA protein DUF1843 PF08898.5 CEP19272.1 - 0.19 11.8 2.5 0.31 11.1 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Lon_C PF05362.8 CEP19273.1 - 1.8e-73 246.1 0.4 4.7e-73 244.8 0.1 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CEP19273.1 - 7.5e-30 104.1 0.4 7.5e-30 104.1 0.3 2.3 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CEP19273.1 - 1.3e-23 83.6 0.0 7.8e-23 81.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 CEP19273.1 - 4.2e-06 26.2 0.0 1.1e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 CEP19273.1 - 8.8e-06 26.5 0.1 4.8e-05 24.1 0.0 2.4 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.1 CEP19273.1 - 2.7e-05 24.2 0.0 0.0001 22.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CEP19273.1 - 3.7e-05 23.4 0.0 0.00011 21.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 CEP19273.1 - 0.00012 20.9 0.0 0.00022 20.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_14 PF13173.1 CEP19273.1 - 0.00037 20.3 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEP19273.1 - 0.0005 19.1 0.0 0.0023 17.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CEP19273.1 - 0.00065 19.8 0.0 0.021 14.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CEP19273.1 - 0.0013 18.3 0.0 0.0039 16.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CEP19273.1 - 0.005 16.0 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CEP19273.1 - 0.0095 16.2 2.6 0.0098 16.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEP19273.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 CEP19273.1 - 0.015 15.2 0.1 0.048 13.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 CEP19273.1 - 0.032 13.6 0.0 0.092 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein ClpB_D2-small PF10431.4 CEP19273.1 - 0.037 13.9 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 1 0 C-terminal, D2-small domain, of ClpB protein AAA_24 PF13479.1 CEP19273.1 - 0.059 12.9 0.2 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP19273.1 - 0.064 12.9 0.0 1 9.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain SKI PF01202.17 CEP19273.1 - 0.073 12.9 1.8 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 CEP19273.1 - 0.095 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CEP19273.1 - 0.11 11.9 0.1 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CEP19273.1 - 0.18 12.1 0.0 0.18 12.1 0.0 3.3 1 1 1 2 2 1 0 AAA domain Occludin_ELL PF07303.8 CEP19273.1 - 7.7 7.3 10.8 12 6.7 0.6 3.1 3 1 0 3 3 2 0 Occludin homology domain Polysacc_deac_1 PF01522.16 CEP19274.1 - 1.8e-36 124.5 0.0 3.3e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP19274.1 - 0.00045 19.2 0.0 0.0011 18.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Pkinase PF00069.20 CEP19275.1 - 8.8e-39 133.2 0.1 1.4e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19275.1 - 5.3e-15 55.1 0.1 2e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CEP19275.1 - 2.7e-05 23.3 0.3 7.3e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CEP19275.1 - 0.0002 20.7 0.0 0.00047 19.5 0.0 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 CEP19275.1 - 0.00044 20.0 0.0 0.00062 19.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP19275.1 - 0.0021 17.0 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CEP19275.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL NMT1 PF09084.6 CEP19275.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like TRAM_LAG1_CLN8 PF03798.11 CEP19276.1 - 8e-33 113.6 25.1 8e-33 113.6 17.4 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CEP19276.1 - 3.2e-15 55.3 0.6 9.7e-15 53.8 0.4 1.9 1 0 0 1 1 1 1 TRAM1-like protein Pkinase PF00069.20 CEP19277.1 - 1e-62 211.6 0.0 1.4e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19277.1 - 4.3e-35 121.0 0.0 6.9e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 CEP19277.1 - 4.5e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.1 CEP19277.1 - 0.00013 21.0 0.0 0.00039 19.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CEP19277.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Usp PF00582.21 CEP19278.1 - 3.2e-20 72.7 1.0 6.6e-20 71.7 0.0 2.0 2 1 0 2 2 2 1 Universal stress protein family PMSI1 PF15322.1 CEP19278.1 - 0.062 12.3 3.6 0.097 11.7 2.5 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Cupin_8 PF13621.1 CEP19279.1 - 3.9e-10 39.6 1.7 5.2e-10 39.2 1.1 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CEP19279.1 - 0.00058 20.0 0.3 0.0021 18.2 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF4237 PF14021.1 CEP19280.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4237) DDE_3 PF13358.1 CEP19281.1 - 0.067 12.9 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease WD40 PF00400.27 CEP19282.1 - 1.4e-23 81.8 3.9 3.1e-06 26.8 0.0 7.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Pkinase PF00069.20 CEP19283.1 - 8e-49 166.1 0.0 9.6e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19283.1 - 1.1e-15 57.3 0.1 2.5e-15 56.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19283.1 - 3e-05 23.1 0.0 8.7e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP19283.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP19283.1 - 0.026 14.2 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Usp PF00582.21 CEP19284.1 - 4.6e-17 62.5 0.0 6.2e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family YchF-GTPase_C PF06071.8 CEP19285.1 - 3.9e-26 90.6 0.0 1.2e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CEP19285.1 - 5e-20 71.5 0.0 9e-20 70.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP19285.1 - 3.7e-08 32.8 0.0 6.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CEP19285.1 - 0.00053 19.8 0.2 1.4 8.7 0.0 3.1 1 1 2 3 3 3 2 Dynamin family AAA_17 PF13207.1 CEP19285.1 - 0.0014 19.4 0.0 0.0041 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CEP19285.1 - 0.0028 17.3 0.0 0.93 9.1 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CEP19285.1 - 0.013 14.3 0.0 0.027 13.2 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 CEP19285.1 - 0.015 14.7 0.0 0.12 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA-like domain PPAK PF02818.10 CEP19285.1 - 0.071 13.0 1.4 0.26 11.2 1.0 2.0 1 0 0 1 1 1 0 PPAK motif RRM_1 PF00076.17 CEP19286.1 - 7.2e-26 89.6 0.0 1.9e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 CEP19286.1 - 2.6e-20 70.6 0.0 1.4e-05 24.2 0.0 6.4 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_5 PF13893.1 CEP19286.1 - 8.9e-17 60.6 0.1 5.1e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP19286.1 - 8e-15 54.5 0.0 2.5e-07 30.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP19286.1 - 0.014 15.2 0.0 6 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.3 CEP19286.1 - 0.07 12.8 0.0 2 8.2 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 bZIP_2 PF07716.10 CEP19287.1 - 0.00041 20.1 12.8 0.00041 20.1 8.9 4.1 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP19287.1 - 0.0076 16.1 7.6 0.0076 16.1 5.3 3.1 3 1 0 3 3 3 1 bZIP transcription factor TSC22 PF01166.13 CEP19287.1 - 0.26 11.2 0.1 0.26 11.2 0.1 3.6 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF972 PF06156.8 CEP19287.1 - 3.1 8.2 9.6 2.1 8.7 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF3605 PF12239.3 CEP19289.1 - 6.6e-27 94.3 3.7 2.8e-26 92.2 2.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) AntA PF08346.7 CEP19289.1 - 0.092 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AntA/AntB antirepressor DPBB_1 PF03330.13 CEP19290.1 - 4.4e-07 29.8 0.4 1.3e-06 28.2 0.2 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP19290.1 - 8.4e-07 28.6 0.3 1.5e-06 27.8 0.2 1.5 1 1 0 1 1 1 1 Barwin family DUF871 PF05913.6 CEP19290.1 - 0.042 12.6 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) DIM PF08194.7 CEP19290.1 - 0.088 12.7 0.3 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 DIM protein ANTH PF07651.11 CEP19291.1 - 6.5e-50 169.4 3.6 8.7e-50 168.9 2.5 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 CEP19291.1 - 5.7e-09 35.9 0.1 1.2e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 ENTH domain HTH_29 PF13551.1 CEP19292.1 - 4.7e-08 33.1 0.0 8.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.1 CEP19292.1 - 0.00022 21.0 0.0 0.0005 19.8 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 CEP19292.1 - 0.0013 18.2 0.0 0.0049 16.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 CEP19292.1 - 0.0037 16.6 0.0 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.1 CEP19292.1 - 0.017 15.1 0.3 0.1 12.5 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2887 PF11103.3 CEP19293.1 - 0.021 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) PDDEXK_2 PF12784.2 CEP19293.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase Spc97_Spc98 PF04130.8 CEP19294.1 - 1e-67 228.6 9.7 1.5e-67 228.1 6.7 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF2413 PF10310.4 CEP19295.1 - 3.8e-63 213.8 20.4 5.3e-63 213.3 14.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Ndc1_Nup PF09531.5 CEP19295.1 - 0.18 10.2 6.6 0.26 9.6 4.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup adh_short PF00106.20 CEP19296.1 - 3.5e-24 85.5 2.6 5.5e-24 84.9 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP19296.1 - 1.8e-13 50.8 0.1 2.7e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP19296.1 - 1.7e-06 27.8 1.2 3e-06 27.0 0.8 1.3 1 0 0 1 1 1 1 KR domain Biotin_lipoyl_2 PF13533.1 CEP19296.1 - 4.3 7.0 6.2 3.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like zf-RVT PF13966.1 CEP19298.1 - 3.4e-08 33.6 1.5 6.4e-08 32.8 1.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PGAP1 PF07819.8 CEP19299.1 - 2.5e-07 30.5 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CEP19299.1 - 2.2e-05 23.8 0.2 0.00037 19.8 0.0 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 CEP19299.1 - 0.00014 21.4 0.1 0.00033 20.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEP19299.1 - 0.00075 19.4 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP19299.1 - 0.0034 17.1 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 CEP19299.1 - 0.0096 14.9 3.3 0.015 14.3 0.0 2.4 3 0 0 3 3 3 1 Lecithin:cholesterol acyltransferase ABC1 PF03109.11 CEP19300.1 - 9.4e-31 106.2 0.1 1.7e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CEP19300.1 - 2.6e-05 23.6 0.1 7.1e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CEP19300.1 - 0.0033 17.1 0.1 0.14 11.8 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 CEP19300.1 - 0.025 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Imm33 PF15580.1 CEP19300.1 - 0.028 13.8 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 33 DNA_primase_S PF01896.14 CEP19300.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit Yip1 PF04893.12 CEP19301.1 - 2.1e-15 56.6 17.3 1.9e-14 53.5 12.0 2.0 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 CEP19301.1 - 1.5 8.4 15.9 3 7.4 11.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Dynamin_N PF00350.18 CEP19302.1 - 7.9e-21 74.5 0.0 5.5e-20 71.8 0.0 2.1 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 CEP19302.1 - 2.4e-20 72.2 0.0 1.7e-19 69.4 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 CEP19302.1 - 2.8e-10 40.1 0.1 9.7e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP19302.1 - 1.8e-06 27.5 0.0 9.2e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEP19302.1 - 2.9e-06 26.5 0.0 4.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP19302.1 - 5.7e-06 26.8 0.0 0.032 14.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein EF-hand_1 PF00036.27 CEP19302.1 - 1.4e-05 24.0 0.2 5.9e-05 22.0 0.2 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CEP19302.1 - 0.00018 21.0 0.0 0.0057 16.4 0.1 3.0 3 0 0 3 3 2 1 EF-hand domain EF-hand_7 PF13499.1 CEP19302.1 - 0.00067 19.7 0.0 0.0021 18.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair FeoB_N PF02421.13 CEP19302.1 - 0.00086 18.6 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B EF-hand_8 PF13833.1 CEP19302.1 - 0.0027 17.2 0.4 0.019 14.5 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair MobB PF03205.9 CEP19302.1 - 0.0097 15.6 0.0 0.055 13.1 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CEP19302.1 - 0.029 13.8 0.0 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CEP19302.1 - 0.033 14.3 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 CEP19302.1 - 0.034 13.3 0.0 0.93 8.6 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit UPF0079 PF02367.12 CEP19302.1 - 0.039 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CEP19302.1 - 0.049 13.5 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain VCBS PF13517.1 CEP19302.1 - 0.091 13.1 0.4 0.23 11.8 0.3 1.7 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AAA_19 PF13245.1 CEP19302.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AIG1 PF04548.11 CEP19302.1 - 0.12 11.4 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Ras PF00071.17 CEP19302.1 - 0.14 11.5 0.1 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Ras family FG-GAP PF01839.18 CEP19302.1 - 0.26 11.0 0.8 0.63 9.8 0.6 1.7 1 0 0 1 1 1 0 FG-GAP repeat Actin PF00022.14 CEP19303.1 - 9.2e-161 534.6 0.0 1e-160 534.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CEP19303.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ecl1 PF12855.2 CEP19305.1 - 2e-07 30.1 8.2 3e-07 29.6 5.7 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 CEP19305.1 - 0.06 13.2 6.9 0.11 12.3 4.8 1.5 1 1 0 1 1 1 0 MYND finger PLATZ PF04640.9 CEP19305.1 - 0.44 10.7 3.9 0.91 9.7 2.7 1.5 1 0 0 1 1 1 0 PLATZ transcription factor DUF3079 PF11278.3 CEP19305.1 - 0.48 10.0 2.7 1 8.9 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) DUF2116 PF09889.4 CEP19305.1 - 1.2 8.9 6.1 2 8.2 4.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Malic_M PF03949.10 CEP19306.1 - 2.3e-79 266.5 0.1 3.2e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CEP19306.1 - 8.3e-56 188.4 0.0 1.4e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SRP_SPB PF02978.14 CEP19306.1 - 0.091 13.0 0.4 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Signal peptide binding domain RGS PF00615.14 CEP19307.1 - 4e-10 39.8 0.5 3.6e-09 36.7 0.4 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain NumbF PF06311.7 CEP19307.1 - 0.046 13.8 1.0 3 8.0 0.0 3.3 2 1 1 3 3 3 0 NUMB domain G_glu_transpept PF01019.16 CEP19308.1 - 1.5e-30 106.2 0.0 1.8e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GLTSCR1 PF15249.1 CEP19311.1 - 2.8e-18 66.0 0.1 2.8e-18 66.0 0.0 3.4 3 1 1 4 4 4 1 Glioma tumor suppressor candidate region Couple_hipA PF13657.1 CEP19311.1 - 0.094 13.0 2.5 1.1 9.6 0.3 3.0 2 0 0 2 2 2 0 HipA N-terminal domain SNase PF00565.12 CEP19312.1 - 5.5e-17 61.9 0.1 3.2e-15 56.2 0.1 2.3 1 1 0 1 1 1 1 Staphylococcal nuclease homologue DUF4473 PF14747.1 CEP19312.1 - 0.11 12.7 0.3 5.2 7.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) DnaJ PF00226.26 CEP19313.1 - 6.3e-22 77.0 3.9 1.8e-21 75.5 2.7 1.8 1 0 0 1 1 1 1 DnaJ domain Vac_ImportDeg PF09783.4 CEP19314.1 - 4.4e-60 202.1 1.7 8.4e-60 201.2 1.2 1.4 1 0 0 1 1 1 1 Vacuolar import and degradation protein CENP-S PF15630.1 CEP19315.1 - 6.1e-19 67.9 0.7 1.1e-18 67.1 0.5 1.6 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CEP19315.1 - 0.0012 18.1 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CEP19315.1 - 0.022 14.5 0.4 0.051 13.2 0.2 1.6 1 1 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CEP19315.1 - 0.035 14.2 0.8 0.075 13.1 0.5 1.7 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 CEP19315.1 - 0.11 12.2 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Paramyxo_C PF01692.13 CEP19316.1 - 0.13 11.8 3.9 0.31 10.6 2.7 1.6 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Suf PF05843.9 CEP19316.1 - 0.35 10.5 4.1 0.39 10.4 2.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.4 CEP19316.1 - 1.9 6.6 7.4 2 6.5 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Polysacc_deac_1 PF01522.16 CEP19317.1 - 5.2e-34 116.5 0.0 8.7e-34 115.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP19317.1 - 5.5e-06 25.5 0.3 2.7e-05 23.2 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 Cyclin PF08613.6 CEP19318.1 - 2.4e-16 60.4 0.5 2.4e-16 60.4 0.3 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CEP19318.1 - 0.00013 21.5 1.2 0.00017 21.1 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Glyco_hydro_9 PF00759.14 CEP19318.1 - 0.0022 16.9 4.1 0.0032 16.4 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Chorion_2 PF03964.10 CEP19318.1 - 0.74 10.3 6.2 1.3 9.5 4.3 1.4 1 0 0 1 1 1 0 Chorion family 2 A_deamin PF02137.13 CEP19319.1 - 2.7e-69 234.0 0.0 2.3e-68 231.0 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain RNB PF00773.14 CEP19320.1 - 1.8e-66 224.6 0.0 1.8e-66 224.6 0.0 2.3 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 CEP19320.1 - 0.73 9.3 2.9 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain ArfGap PF01412.13 CEP19321.1 - 1.8e-36 124.4 0.0 5.9e-36 122.8 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CotH PF08757.6 CEP19322.1 - 1.8e-33 116.1 2.1 1.8e-33 116.1 1.5 1.5 2 0 0 2 2 2 1 CotH protein rve PF00665.21 CEP19323.1 - 2.9e-07 30.5 0.1 7.8e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Exo_endo_phos_2 PF14529.1 CEP19324.1 - 2.5e-10 39.9 0.1 3.1e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP19324.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family AP4E_app_platf PF14807.1 CEP19324.1 - 0.014 15.6 0.1 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Helitron_like_N PF14214.1 CEP19325.1 - 2.4e-19 69.8 1.1 1.1e-18 67.6 0.0 1.9 1 1 1 2 2 2 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.1 CEP19328.1 - 4.5e-28 98.2 0.0 6e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 CEP19329.1 - 1.2e-39 136.3 0.2 5.1e-21 75.0 0.0 3.6 1 1 2 3 3 3 3 PIF1-like helicase IncA PF04156.9 CEP19331.1 - 0.0009 18.8 26.5 0.00097 18.7 18.4 1.1 1 0 0 1 1 1 1 IncA protein TCP PF03634.8 CEP19331.1 - 0.0098 16.2 12.8 0.013 15.8 8.8 1.2 1 0 0 1 1 1 1 TCP family transcription factor TMEM51 PF15345.1 CEP19331.1 - 0.011 15.3 10.4 0.013 15.2 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2009 PF09418.5 CEP19331.1 - 0.025 13.3 7.7 0.028 13.2 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) PAT1 PF09770.4 CEP19331.1 - 0.031 12.5 28.1 0.03 12.5 19.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.7 CEP19331.1 - 0.035 11.8 9.9 0.036 11.8 6.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MOR2-PAG1_N PF14222.1 CEP19331.1 - 0.038 12.6 5.5 0.039 12.6 3.8 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal AUX_IAA PF02309.11 CEP19331.1 - 0.041 13.6 8.7 0.043 13.5 6.0 1.1 1 0 0 1 1 1 0 AUX/IAA family Pex14_N PF04695.8 CEP19331.1 - 0.044 13.8 15.4 0.053 13.5 10.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PP31 PF05311.6 CEP19331.1 - 0.049 12.8 10.6 0.057 12.6 7.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4175 PF13779.1 CEP19331.1 - 0.099 10.3 39.5 0.1 10.2 27.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.11 CEP19331.1 - 0.13 12.0 6.4 0.15 11.9 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1943 PF09172.6 CEP19331.1 - 0.14 11.0 9.4 0.18 10.6 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4011 PF13195.1 CEP19331.1 - 0.19 11.7 8.8 0.21 11.5 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) CPSF100_C PF13299.1 CEP19331.1 - 0.2 11.8 7.0 0.22 11.6 4.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpaB_C PF14028.1 CEP19331.1 - 0.27 10.7 2.7 0.29 10.6 1.9 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain Med15 PF09606.5 CEP19331.1 - 0.38 8.8 42.5 0.36 8.9 29.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0560 PF10577.4 CEP19331.1 - 0.48 8.6 16.9 0.5 8.5 11.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RR_TM4-6 PF06459.7 CEP19331.1 - 0.48 10.2 9.9 0.54 10.1 6.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CEP19331.1 - 0.58 9.9 9.8 0.56 9.9 6.8 1.1 1 0 0 1 1 1 0 DDHD domain AIF_C PF14721.1 CEP19331.1 - 0.58 10.4 7.4 0.8 9.9 5.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Gag_spuma PF03276.9 CEP19331.1 - 0.61 8.3 23.5 0.65 8.2 16.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Peptidase_U57 PF05582.7 CEP19331.1 - 0.62 8.9 7.5 0.71 8.7 5.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF4557 PF15101.1 CEP19331.1 - 0.68 9.7 22.2 0.81 9.4 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pex16 PF08610.5 CEP19331.1 - 0.69 8.8 11.3 0.76 8.7 7.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FliP PF00813.15 CEP19331.1 - 0.74 9.4 3.4 0.81 9.3 2.3 1.2 1 0 0 1 1 1 0 FliP family CBF PF03914.12 CEP19331.1 - 0.84 9.0 5.4 1.2 8.5 3.8 1.4 1 1 0 1 1 1 0 CBF/Mak21 family Glyco_transf_15 PF01793.11 CEP19331.1 - 0.89 8.4 11.0 1 8.2 7.6 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Bud13 PF09736.4 CEP19331.1 - 1.1 9.5 22.1 1.4 9.1 15.3 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Ndc1_Nup PF09531.5 CEP19331.1 - 1.1 7.5 12.1 1.3 7.3 8.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Folate_carrier PF01770.13 CEP19331.1 - 1.2 7.6 4.3 1.1 7.6 3.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Serinc PF03348.10 CEP19331.1 - 1.2 7.7 9.6 1.4 7.5 6.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FYDLN_acid PF09538.5 CEP19331.1 - 1.2 9.6 7.8 1.6 9.3 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Paramyxo_ncap PF00973.14 CEP19331.1 - 1.3 7.6 9.6 1.3 7.5 6.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ycf1 PF05758.7 CEP19331.1 - 1.6 6.3 15.0 1.5 6.4 10.4 1.0 1 0 0 1 1 1 0 Ycf1 DUF853 PF05872.7 CEP19331.1 - 1.6 7.0 9.2 1.7 6.9 6.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SprA-related PF12118.3 CEP19331.1 - 1.8 7.7 30.1 2.3 7.4 20.9 1.1 1 0 0 1 1 1 0 SprA-related family MMR1 PF08505.5 CEP19331.1 - 1.9 8.4 19.1 2 8.3 13.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Mem_trans PF03547.13 CEP19331.1 - 1.9 6.6 6.2 2 6.5 4.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF2215 PF10225.4 CEP19331.1 - 1.9 7.8 6.8 2.3 7.5 4.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) GPCR_chapero_1 PF11904.3 CEP19331.1 - 2.1 7.4 14.0 2.5 7.1 9.7 1.0 1 0 0 1 1 1 0 GPCR-chaperone Band_3_cyto PF07565.8 CEP19331.1 - 2.1 7.7 11.4 2.5 7.5 7.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S15 PF02129.13 CEP19331.1 - 2.4 7.4 10.1 2.8 7.3 7.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DHHW PF14286.1 CEP19331.1 - 3 7.0 9.3 3.3 6.9 6.4 1.1 1 0 0 1 1 1 0 DHHW protein FHIPEP PF00771.15 CEP19331.1 - 3.1 6.0 9.1 3.4 5.8 6.3 1.1 1 0 0 1 1 1 0 FHIPEP family SPX PF03105.14 CEP19331.1 - 3.5 7.3 17.0 4.1 7.0 11.8 1.1 1 0 0 1 1 1 0 SPX domain Peptidase_C6 PF00851.13 CEP19331.1 - 3.8 6.0 12.7 4.4 5.8 8.8 1.0 1 0 0 1 1 1 0 Helper component proteinase Raptor_N PF14538.1 CEP19331.1 - 3.9 7.2 12.9 5.7 6.7 9.0 1.2 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Gti1_Pac2 PF09729.4 CEP19331.1 - 4 7.2 8.6 4.6 7.0 5.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Cellulose_synt PF03552.9 CEP19331.1 - 4.1 5.5 5.8 4.5 5.4 4.0 1.1 1 0 0 1 1 1 0 Cellulose synthase SID-1_RNA_chan PF13965.1 CEP19331.1 - 4.4 5.3 7.7 4.6 5.2 5.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.2 CEP19331.1 - 4.5 4.8 14.8 4.7 4.7 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Membralin PF09746.4 CEP19331.1 - 4.8 6.1 7.3 5.4 5.9 5.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein HSP70 PF00012.15 CEP19331.1 - 5.3 4.8 14.3 5.7 4.7 9.9 1.0 1 0 0 1 1 1 0 Hsp70 protein TMEM237 PF15383.1 CEP19331.1 - 5.6 6.0 13.2 6.7 5.7 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 DUF3306 PF11748.3 CEP19331.1 - 5.6 7.6 14.5 7.9 7.1 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) ARD PF03079.9 CEP19331.1 - 7.6 6.4 10.0 9.6 6.1 6.9 1.1 1 0 0 1 1 1 0 ARD/ARD' family DUF342 PF03961.8 CEP19331.1 - 8.5 4.6 14.9 9.5 4.5 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3464 PF11947.3 CEP19331.1 - 8.8 5.7 9.1 11 5.4 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF1980 PF09323.5 CEP19331.1 - 9.4 5.9 8.7 10 5.8 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DDE_Tnp_1_7 PF13843.1 CEP19333.1 - 2.3e-27 95.9 0.0 3.6e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.16 CEP19333.1 - 0.0069 15.9 0.0 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain PIF1 PF05970.9 CEP19335.1 - 4e-20 72.0 0.0 1.1e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP19335.1 - 0.00019 19.3 0.0 0.00027 18.8 0.0 1.1 1 0 0 1 1 1 1 Helicase BAH PF01426.13 CEP19335.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 BAH domain UvrD_C_2 PF13538.1 CEP19335.1 - 0.042 13.9 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 CEP19336.1 - 1.9e-69 234.3 0.0 2.9e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 CEP19336.1 - 1.3e-05 24.7 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CEP19336.1 - 3.6e-05 23.6 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CEP19336.1 - 0.00016 21.3 0.0 0.0003 20.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEP19336.1 - 0.0034 17.1 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TFX_C PF14601.1 CEP19336.1 - 0.0039 16.9 0.3 3 7.7 0.0 2.5 2 0 0 2 2 2 2 DNA_binding protein, TFX, C-term T2SE PF00437.15 CEP19336.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 CEP19336.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEP19336.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.1 CEP19336.1 - 0.04 13.5 2.2 0.047 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CEP19336.1 - 0.044 13.9 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 CEP19336.1 - 0.046 12.6 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 CEP19336.1 - 0.053 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CEP19336.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 CEP19336.1 - 0.09 12.9 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 CEP19336.1 - 0.094 11.3 0.1 0.2 10.2 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_2 PF03668.10 CEP19336.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop ATPase protein family AAA_18 PF13238.1 CEP19336.1 - 0.16 12.2 0.1 0.76 10.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 CEP19336.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1292 PF06949.6 CEP19336.1 - 0.17 12.2 0.5 37 4.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) DDE_3 PF13358.1 CEP19339.1 - 9.6e-12 44.8 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_A_exo1 PF01612.15 CEP19341.1 - 0.0046 16.4 0.1 0.0068 15.8 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease OrfB_Zn_ribbon PF07282.6 CEP19343.1 - 0.00042 19.9 1.5 0.00081 18.9 1.0 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Bmp PF02608.9 CEP19343.1 - 0.035 12.8 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Basic membrane protein Rib_5-P_isom_A PF06026.9 CEP19344.1 - 7.2e-56 188.2 0.0 8.7e-56 187.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF1279 PF06916.8 CEP19345.1 - 3e-15 56.2 0.0 6.5e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) FLO_LFY PF01698.11 CEP19345.1 - 0.017 13.9 0.0 0.024 13.5 0.0 1.2 1 1 0 1 1 1 0 Floricaula / Leafy protein DUF4620 PF15399.1 CEP19345.1 - 0.061 13.4 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Molydop_binding PF01568.16 CEP19345.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain WD40 PF00400.27 CEP19346.1 - 8.6e-55 180.7 27.8 1.2e-09 37.6 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEP19346.1 - 1.8e-10 39.6 17.4 0.0099 14.0 0.0 5.8 3 1 2 6 6 6 4 Nucleoporin Nup120/160 F-box-like PF12937.2 CEP19346.1 - 3.6e-07 29.8 1.2 8.5e-07 28.6 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP19346.1 - 4e-06 26.3 0.8 8.8e-06 25.2 0.5 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 CEP19346.1 - 1.2e-05 24.9 0.9 6.6e-05 22.4 0.2 2.4 2 1 0 2 2 2 1 PQQ-like domain HSP70 PF00012.15 CEP19347.1 - 1.1e-167 558.5 6.7 1.1e-167 558.5 4.7 1.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CEP19347.1 - 5.3e-12 44.9 1.2 2.8e-11 42.6 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CEP19347.1 - 0.0091 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Thi4 PF01946.12 CEP19347.1 - 0.055 12.5 0.1 0.26 10.3 0.0 2.0 1 1 1 2 2 2 0 Thi4 family Ketoacyl-synt_C PF02801.17 CEP19347.1 - 0.08 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain CDC37_C PF08564.5 CEP19347.1 - 0.35 10.7 6.5 3.9 7.3 0.7 2.9 2 0 0 2 2 2 0 Cdc37 C terminal domain GATase_7 PF13537.1 CEP19349.1 - 4.8e-14 52.1 0.0 9.2e-14 51.2 0.0 1.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CEP19349.1 - 8.5e-14 51.6 0.0 1.4e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CEP19349.1 - 1.9e-08 33.4 0.4 0.00022 20.0 0.1 2.0 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Asn_synthase PF00733.16 CEP19350.1 - 4e-73 246.0 0.0 5.2e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CEP19350.1 - 1.6e-15 56.9 0.0 3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CEP19350.1 - 2.4e-10 39.9 0.0 4.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.1 CEP19350.1 - 1.1e-07 31.8 0.0 4.5e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 CEP19350.1 - 0.012 14.5 0.0 0.033 13.1 0.0 1.6 2 0 0 2 2 2 0 NAD synthase QueC PF06508.8 CEP19350.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC GATA PF00320.22 CEP19351.1 - 6.4e-16 57.4 4.2 6.4e-16 57.4 2.9 2.4 2 0 0 2 2 2 1 GATA zinc finger RRN7 PF11781.3 CEP19351.1 - 0.00039 19.8 0.3 0.00039 19.8 0.2 2.7 3 0 0 3 3 3 1 RNA polymerase I-specific transcription initiation factor Rrn7 COX5B PF01215.14 CEP19351.1 - 0.0071 16.0 1.8 0.14 11.7 0.1 3.0 3 0 0 3 3 3 1 Cytochrome c oxidase subunit Vb TF_Zn_Ribbon PF08271.7 CEP19351.1 - 0.04 13.2 0.2 0.04 13.2 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 CEP19351.1 - 0.043 13.4 0.5 0.15 11.7 0.4 1.9 1 0 0 1 1 1 0 Domain found in IF2B/IF5 ArfGap PF01412.13 CEP19351.1 - 0.049 13.4 7.6 0.068 12.9 1.7 2.6 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf CDC37_N PF03234.9 CEP19351.1 - 0.096 13.0 2.5 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding IncA PF04156.9 CEP19351.1 - 0.29 10.7 4.2 0.42 10.1 0.2 2.3 3 0 0 3 3 3 0 IncA protein TGF_beta_GS PF08515.7 CEP19351.1 - 0.81 9.0 3.9 1.7 8.0 2.7 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Lzipper-MIP1 PF14389.1 CEP19351.1 - 1 9.5 6.3 1.5 8.9 0.5 3.1 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DZR PF12773.2 CEP19351.1 - 8.9 6.2 13.6 8.5e+02 -0.2 9.4 3.3 1 1 0 1 1 1 0 Double zinc ribbon DDE_3 PF13358.1 CEP19352.1 - 5.1e-18 65.2 0.0 8e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Beta-Casp PF10996.3 CEP19353.1 - 3.3e-08 33.5 3.3 2.2e-07 30.8 0.0 3.5 3 1 0 3 3 3 1 Beta-Casp domain Carboxyl_trans PF01039.17 CEP19353.1 - 1.4 7.1 4.9 0.48 8.7 0.0 2.1 2 0 0 2 2 2 0 Carboxyl transferase domain Thg1 PF04446.7 CEP19354.1 - 1.4e-47 160.6 0.3 2e-47 160.1 0.2 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 CEP19354.1 - 2e-47 159.8 0.2 2.9e-47 159.3 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Peptidase_S10 PF00450.17 CEP19355.1 - 8.5e-88 295.2 1.1 9.6e-88 295.1 0.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Zn_Tnp_IS91 PF14319.1 CEP19355.1 - 0.022 14.2 0.5 0.04 13.4 0.4 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain CD20 PF04103.10 CEP19356.1 - 0.0031 17.4 0.8 0.012 15.5 0.0 2.3 1 1 0 2 2 2 1 CD20-like family DNase-RNase PF02577.9 CEP19356.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease PrgI PF12666.2 CEP19356.1 - 0.29 11.3 7.5 4 7.6 0.3 2.4 2 0 0 2 2 2 0 PrgI family protein Tmemb_14 PF03647.8 CEP19356.1 - 0.3 11.5 5.0 0.45 10.9 0.9 2.3 2 0 0 2 2 2 0 Transmembrane proteins 14C BTP PF05232.7 CEP19356.1 - 0.96 9.2 6.8 3 7.6 4.7 1.8 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family EamA PF00892.15 CEP19356.1 - 9.5 6.2 18.1 7.6 6.5 4.8 2.5 2 1 0 2 2 2 0 EamA-like transporter family TRAPP PF04051.11 CEP19357.1 - 7.9e-40 135.8 0.0 1e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.5 CEP19357.1 - 0.0078 16.0 0.0 0.63 9.8 0.0 2.1 2 0 0 2 2 2 2 Putative redox-active protein (C_GCAxxG_C_C) Carboxyl_trans PF01039.17 CEP19358.1 - 1.1e-147 492.3 0.0 1.6e-147 491.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH PF00378.15 CEP19359.1 - 6.9e-22 77.7 0.0 9.4e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CEP19359.1 - 9.6e-18 64.4 0.1 2.9e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Hydrolase_3 PF08282.7 CEP19359.1 - 0.077 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ECH_C PF13766.1 CEP19360.1 - 2.7e-14 53.3 0.4 5.4e-14 52.3 0.1 1.5 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CEP19360.1 - 1.7e-08 33.8 0.0 2.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SET PF00856.23 CEP19361.1 - 0.0014 18.9 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 SET domain RRM_1 PF00076.17 CEP19362.1 - 5.1e-30 102.9 0.3 7.8e-16 57.4 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP19362.1 - 3.6e-18 65.3 0.1 4.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP19362.1 - 4e-12 45.8 0.1 5.1e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEP19362.1 - 4e-07 29.8 0.2 0.00068 19.4 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 CEP19362.1 - 0.00021 21.0 3.7 0.1 12.3 0.1 2.5 2 0 0 2 2 2 2 Limkain b1 DbpA PF03880.10 CEP19362.1 - 0.06 13.0 0.2 2.1 8.0 0.0 2.5 2 1 0 2 2 2 0 DbpA RNA binding domain DUF605 PF04652.11 CEP19362.1 - 1.5 8.1 11.5 1.8 7.9 8.0 1.1 1 0 0 1 1 1 0 Vta1 like YtxC PF08812.6 CEP19364.1 - 0.0021 17.5 0.1 0.0027 17.2 0.1 1.2 1 0 0 1 1 1 1 YtxC-like family Ras PF00071.17 CEP19365.1 - 3.4e-53 179.3 0.0 3.9e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP19365.1 - 7.3e-16 58.7 0.0 1.1e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEP19365.1 - 1.1e-07 31.3 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AATase PF07247.7 CEP19366.1 - 3.1e-23 82.0 0.0 4.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CEP19366.1 - 2.7e-19 69.1 0.6 9.7e-14 50.9 0.9 2.3 2 0 0 2 2 2 2 Condensation domain Transferase PF02458.10 CEP19366.1 - 9.4e-05 21.0 0.0 0.11 10.9 0.0 2.2 2 0 0 2 2 2 2 Transferase family Mito_carr PF00153.22 CEP19367.1 - 5.8e-65 215.0 0.1 3.9e-23 80.9 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein MBOAT_2 PF13813.1 CEP19368.1 - 1.3e-18 66.8 0.2 3.5e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family FGGY_N PF00370.16 CEP19369.1 - 5.9e-26 91.2 0.0 1.4e-23 83.4 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CEP19369.1 - 1.4e-21 77.0 0.0 2.7e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain WD40 PF00400.27 CEP19370.1 - 5.8e-66 216.1 26.6 4.5e-10 39.0 0.7 13.6 13 0 0 13 13 13 12 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEP19370.1 - 0.0092 14.7 4.2 0.076 11.7 0.0 3.6 3 1 0 4 4 4 1 Nup133 N terminal like CK2S PF15011.1 CEP19371.1 - 3e-05 23.8 4.3 6.1e-05 22.8 1.9 2.3 1 1 1 2 2 2 1 Casein Kinase 2 substrate BAP PF06639.6 CEP19371.1 - 0.053 13.2 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) Med21 PF11221.3 CEP19371.1 - 0.13 12.2 1.9 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Ribosomal_L2_C PF03947.13 CEP19372.1 - 2.9e-42 143.5 2.1 2.9e-42 143.5 1.5 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CEP19372.1 - 1.8e-15 56.6 0.1 3.9e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain ThiF PF00899.16 CEP19373.1 - 9.9e-38 129.0 0.2 1.7e-37 128.2 0.1 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 CEP19373.1 - 0.0008 18.4 0.2 0.0017 17.4 0.1 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CEP19373.1 - 0.0062 16.6 0.1 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CEP19373.1 - 0.0065 15.5 0.2 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEP19373.1 - 0.019 13.8 0.4 0.035 13.0 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1131 PF06572.7 CEP19373.1 - 0.035 13.5 0.1 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1131) NAD_binding_7 PF13241.1 CEP19373.1 - 0.048 13.9 0.1 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 CEP19373.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 CEP19373.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 CEP19373.1 - 0.099 12.0 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CEP19373.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CEP19373.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ELFV_dehydrog PF00208.16 CEP19373.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Adaptin_N PF01602.15 CEP19374.1 - 2.2e-113 379.3 1.8 2.9e-113 378.9 1.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CEP19374.1 - 2.9e-58 195.9 0.9 6e-58 194.9 0.6 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CEP19374.1 - 1.9e-16 60.1 2.5 0.00086 19.5 0.1 5.9 2 2 4 6 6 6 4 HEAT repeats Rad60-SLD_2 PF13881.1 CEP19374.1 - 0.0065 16.3 0.0 0.076 12.9 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2452 PF10504.4 CEP19374.1 - 0.018 14.3 0.1 0.54 9.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2452) HEAT_PBS PF03130.11 CEP19374.1 - 0.095 13.2 8.9 1.2 9.8 0.0 5.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat HEAT PF02985.17 CEP19374.1 - 0.53 10.5 13.3 8 6.8 0.1 6.5 9 0 0 9 9 9 0 HEAT repeat Pex2_Pex12 PF04757.9 CEP19375.1 - 2e-51 174.5 6.5 2.5e-51 174.3 4.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CEP19375.1 - 1.1e-08 34.9 2.0 1.7e-08 34.3 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEP19375.1 - 2.1e-06 27.4 2.0 3.3e-06 26.8 1.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP19375.1 - 5.5e-06 25.9 0.4 8.6e-06 25.3 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP19375.1 - 0.0027 17.3 1.0 0.0045 16.6 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEP19375.1 - 0.0043 16.8 4.9 0.0082 16.0 3.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Tubulin PF00091.20 CEP19376.1 - 2.2e-73 246.6 0.0 4.7e-73 245.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEP19376.1 - 9.2e-48 161.4 0.1 1.4e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CEP19376.1 - 5.4e-06 26.4 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CEP19376.1 - 0.084 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain SLX9 PF15341.1 CEP19377.1 - 6.6e-20 71.7 19.0 6.6e-20 71.7 13.1 1.5 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Guanylate_kin PF00625.16 CEP19377.1 - 0.097 12.1 0.1 0.097 12.1 0.1 2.5 2 1 1 3 3 3 0 Guanylate kinase Hom_end_hint PF05203.11 CEP19377.1 - 0.39 10.4 9.7 0.57 9.8 6.6 1.3 1 1 0 1 1 1 0 Hom_end-associated Hint FERM_M PF00373.13 CEP19377.1 - 2.3 8.4 8.0 3.2 7.9 0.2 2.1 2 0 0 2 2 2 0 FERM central domain RNA_pol_Rpb1_5 PF04998.12 CEP19377.1 - 5.7 6.1 7.1 7.6 5.7 4.9 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Aminotran_1_2 PF00155.16 CEP19378.1 - 2.2e-75 253.8 0.0 2.7e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CEP19378.1 - 1.2e-06 27.1 0.0 1.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CEP19378.1 - 0.00014 20.7 0.0 0.00026 19.8 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CEP19378.1 - 0.00032 19.9 0.1 0.00095 18.3 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase PAS_9 PF13426.1 CEP19380.1 - 4.2e-27 94.5 0.0 2.5e-19 69.5 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 CEP19380.1 - 4.1e-20 71.6 0.0 6.1e-11 42.2 0.0 3.8 3 1 0 3 3 3 3 PAS fold PAS PF00989.19 CEP19380.1 - 3.1e-11 43.0 0.0 3e-05 23.7 0.0 2.9 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.5 CEP19380.1 - 1e-08 35.1 0.0 0.00034 20.6 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 CEP19380.1 - 1.5e-08 34.5 0.0 1.9e-05 24.5 0.0 3.5 4 0 0 4 4 4 2 PAS domain PAS_8 PF13188.1 CEP19380.1 - 0.025 14.4 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 PAS domain F-box-like PF12937.2 CEP19381.1 - 1.1e-09 37.8 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like Suf PF05843.9 CEP19381.1 - 0.0029 17.3 3.8 0.0029 17.3 2.6 2.1 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) FHIPEP PF00771.15 CEP19381.1 - 0.01 14.1 1.3 0.016 13.5 0.9 1.2 1 0 0 1 1 1 0 FHIPEP family Serinc PF03348.10 CEP19381.1 - 0.038 12.7 1.0 0.061 12.0 0.7 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) F-box PF00646.28 CEP19381.1 - 0.041 13.5 0.1 0.18 11.5 0.1 2.1 1 1 0 1 1 1 0 F-box domain Ctr PF04145.10 CEP19381.1 - 0.084 12.9 0.2 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 Ctr copper transporter family RED_N PF07808.8 CEP19381.1 - 0.096 11.8 17.3 0.42 9.7 9.9 2.3 2 0 0 2 2 2 0 RED-like protein N-terminal region DivIC PF04977.10 CEP19381.1 - 0.14 11.6 17.5 0.31 10.5 12.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Peptidase_S15 PF02129.13 CEP19381.1 - 0.24 10.7 6.2 0.11 11.8 2.3 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) K_trans PF02705.11 CEP19381.1 - 0.32 9.3 0.1 0.47 8.7 0.0 1.1 1 0 0 1 1 1 0 K+ potassium transporter OATP PF03137.15 CEP19381.1 - 0.97 7.4 4.7 1.7 6.6 3.2 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.8 CEP19381.1 - 1.1 9.2 17.5 0.44 10.5 6.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.8 CEP19381.1 - 3.2 7.1 9.8 1.5 8.2 3.5 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CD20 PF04103.10 CEP19381.1 - 5.4 6.9 4.3 2.8 7.8 0.5 2.2 2 0 0 2 2 2 0 CD20-like family Gag_spuma PF03276.9 CEP19381.1 - 5.6 5.1 19.8 9.3 4.4 13.8 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF3185 PF11381.3 CEP19383.1 - 0.053 13.2 1.3 0.088 12.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) PAP2 PF01569.16 CEP19383.1 - 0.17 11.5 2.9 0.6 9.7 2.0 2.1 1 1 0 1 1 1 0 PAP2 superfamily DUF4064 PF13273.1 CEP19383.1 - 0.18 11.9 1.0 18 5.4 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Brr6_like_C_C PF10104.4 CEP19383.1 - 0.22 11.0 2.0 5.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Kei1 PF08552.6 CEP19383.1 - 1.4 8.5 7.1 4.8 6.7 0.1 2.7 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 SKG6 PF08693.5 CEP19384.1 - 0.013 14.7 2.8 0.028 13.7 1.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PsbJ PF01788.12 CEP19384.1 - 0.072 12.6 1.8 0.15 11.6 1.3 1.5 1 0 0 1 1 1 0 PsbJ Romo1 PF10247.4 CEP19384.1 - 0.08 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 BTB_2 PF02214.17 CEP19385.1 - 1.2e-18 67.1 0.1 3.2e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain CNH PF00780.17 CEP19386.1 - 7.8e-40 137.0 0.0 2e-33 116.0 0.0 2.4 2 0 0 2 2 2 2 CNH domain RhoGEF PF00621.15 CEP19386.1 - 3.2e-36 124.8 2.5 7.6e-36 123.6 1.7 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 CEP19386.1 - 2.3e-18 66.4 0.0 7.9e-18 64.7 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4203 PF13886.1 CEP19387.1 - 7.1e-07 28.9 33.8 6e-06 25.8 23.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) DUF872 PF05915.7 CEP19387.1 - 0.088 12.6 0.0 0.088 12.6 0.0 3.0 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) PsbH PF00737.15 CEP19387.1 - 0.14 11.8 0.2 0.14 11.8 0.1 2.7 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein FAM183 PF14886.1 CEP19388.1 - 0.32 11.5 5.5 0.49 10.9 3.8 1.2 1 0 0 1 1 1 0 FAM183A and FAM183B related SDH_alpha PF03313.10 CEP19388.1 - 0.36 9.8 1.6 0.4 9.6 0.4 1.5 1 1 1 2 2 2 0 Serine dehydratase alpha chain Pkinase PF00069.20 CEP19389.1 - 5.1e-65 219.1 0.1 4.4e-64 216.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19389.1 - 1.9e-44 151.7 0.0 4.6e-44 150.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CEP19389.1 - 9.6e-06 24.8 0.1 2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CEP19389.1 - 0.00062 19.1 0.2 0.0014 17.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CEP19389.1 - 0.00097 18.1 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEP19389.1 - 0.0018 18.0 0.2 0.26 10.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Ank_2 PF12796.2 CEP19390.1 - 6e-42 141.8 0.1 4.2e-16 59.0 0.0 3.7 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 CEP19390.1 - 6.4e-25 85.6 0.1 1.2e-05 24.8 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 CEP19390.1 - 5.6e-20 69.4 0.1 5.6e-05 22.9 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CEP19390.1 - 2.2e-18 66.2 0.0 1.6e-05 25.2 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEP19390.1 - 2.2e-15 56.2 0.1 0.00018 21.6 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Zn_clus PF00172.13 CEP19391.1 - 0.00059 19.6 9.0 0.0011 18.8 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain STE PF02200.11 CEP19392.1 - 1.1e-56 189.6 0.2 2.2e-56 188.6 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 CEP19392.1 - 4.8e-11 42.3 10.5 4.9e-06 26.5 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP19392.1 - 4.2e-09 36.1 8.0 0.0007 19.7 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP19392.1 - 2.7e-08 33.6 2.7 2.7e-08 33.6 1.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEP19392.1 - 0.00018 21.2 1.7 0.0012 18.6 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP19392.1 - 0.0012 18.9 4.6 0.073 13.2 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 CEP19392.1 - 0.15 11.7 1.1 1.2 8.8 0.0 2.6 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-met PF12874.2 CEP19392.1 - 1.4 9.2 5.0 3.6 7.9 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Sterol_MT_C PF08498.5 CEP19393.1 - 6.8e-28 96.4 1.7 1.1e-27 95.7 1.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CEP19393.1 - 6.2e-23 81.1 0.0 3.2e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP19393.1 - 1.3e-18 66.9 0.0 2.1e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP19393.1 - 4.3e-13 49.5 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP19393.1 - 5.4e-13 48.9 0.1 9.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP19393.1 - 9.3e-12 45.2 0.0 2.8e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEP19393.1 - 9.5e-12 44.5 0.1 1.4e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 CEP19393.1 - 1.3e-11 44.0 0.0 2.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CEP19393.1 - 8.3e-10 39.2 0.0 2.4e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP19393.1 - 3.3e-08 33.5 0.0 1.1e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEP19393.1 - 2.2e-05 23.9 0.0 5.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 CEP19393.1 - 0.0086 15.6 0.1 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 CEP19393.1 - 0.047 13.2 0.1 0.15 11.5 0.1 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CEP19393.1 - 0.096 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 CEP19393.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PITH PF06201.8 CEP19394.1 - 9e-48 161.8 0.3 1.1e-47 161.6 0.2 1.1 1 0 0 1 1 1 1 PITH domain Nuc_sug_transp PF04142.10 CEP19395.1 - 1.1e-93 312.8 11.7 1.6e-93 312.3 8.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 CEP19395.1 - 7.5e-08 32.5 3.2 7.5e-08 32.5 2.2 2.6 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 CEP19395.1 - 2.5e-06 27.5 21.7 2.7e-06 27.4 2.6 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CEP19395.1 - 1.5e-05 24.1 18.8 4.2e-05 22.6 13.1 1.8 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CEP19395.1 - 0.00036 20.2 2.3 0.00036 20.2 1.6 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family BsuPI PF12690.2 CEP19396.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Rpr2 PF04032.11 CEP19397.1 - 9.5e-15 54.2 2.9 2.1e-14 53.1 2.0 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain CENP-B_N PF04218.8 CEP19397.1 - 0.018 14.4 0.8 0.063 12.7 0.6 2.0 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain AKAP95 PF04988.7 CEP19397.1 - 0.062 13.0 3.9 0.028 14.2 0.9 1.7 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Nudix_N_2 PF14803.1 CEP19397.1 - 0.096 12.3 0.6 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Nudix N-terminal FUR PF01475.14 CEP19397.1 - 0.12 12.3 1.5 0.33 10.8 0.3 2.0 1 1 1 2 2 2 0 Ferric uptake regulator family Topoisom_I_N PF02919.10 CEP19397.1 - 6.8 5.9 7.6 1.3 8.2 1.6 1.9 1 1 1 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment HMG_box PF00505.14 CEP19398.1 - 5.3e-16 58.6 0.9 1.8e-15 56.9 0.6 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEP19398.1 - 9.6e-11 41.8 0.7 9.6e-11 41.8 0.5 3.1 3 1 1 4 4 4 1 HMG-box domain SAM_2 PF07647.12 CEP19398.1 - 0.00021 21.0 0.1 0.00061 19.5 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEP19398.1 - 0.00039 20.5 1.7 0.0012 18.9 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) zf-C2H2 PF00096.21 CEP19399.1 - 1.4e-06 28.3 2.2 1.4e-06 28.3 1.5 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP19399.1 - 0.00014 21.9 1.1 0.00037 20.6 0.8 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger MIS13 PF08202.6 CEP19399.1 - 0.025 13.6 0.9 0.033 13.2 0.7 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Ogr_Delta PF04606.7 CEP19399.1 - 0.054 13.1 1.3 0.14 11.8 0.2 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_2 PF13465.1 CEP19399.1 - 0.19 12.0 8.0 4.8 7.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain DUF1358 PF07096.6 CEP19400.1 - 2e-07 30.7 0.2 3.8e-07 29.8 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1358) DUF1469 PF07332.6 CEP19400.1 - 0.72 9.5 3.5 7.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Hydrolase_6 PF13344.1 CEP19401.1 - 2.5e-26 91.5 0.0 4.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP19401.1 - 1.5e-14 53.4 0.0 9e-14 50.9 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 CEP19401.1 - 3.7e-05 24.0 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP19401.1 - 0.00014 22.4 0.0 0.00056 20.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2618 PF10940.3 CEP19403.1 - 0.054 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) DUF4482 PF14818.1 CEP19405.1 - 0.0016 19.1 2.5 0.006 17.2 1.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4482) HD_3 PF13023.1 CEP19405.1 - 0.007 16.1 0.8 0.09 12.5 0.0 2.2 1 1 0 2 2 2 1 HD domain VTC PF09359.5 CEP19406.1 - 1.1e-84 283.8 0.0 2.3e-84 282.7 0.0 1.6 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEP19406.1 - 1.4e-20 74.1 9.8 3.1e-08 33.7 0.5 3.8 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.10 CEP19406.1 - 4.3e-12 46.0 3.0 9.6e-12 44.9 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Arm PF00514.18 CEP19406.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat VTC PF09359.5 CEP19407.1 - 8e-50 169.4 0.2 2.1e-49 168.0 0.1 1.7 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEP19407.1 - 1.6e-17 64.2 14.9 9.1e-09 35.4 0.8 4.0 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 CEP19407.1 - 5e-11 42.6 2.0 5e-11 42.6 1.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) VTC PF09359.5 CEP19408.1 - 7.3e-85 284.4 0.4 7.3e-85 284.4 0.3 2.2 3 0 0 3 3 3 1 VTC domain SPX PF03105.14 CEP19408.1 - 2.3e-12 47.2 17.2 9.8e-08 32.1 2.3 3.9 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 CEP19408.1 - 2e-09 37.5 3.5 2e-09 37.5 2.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) 6PF2K PF01591.13 CEP19410.1 - 2.7e-69 232.6 1.1 4.1e-69 232.0 0.8 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEP19410.1 - 1.8e-31 109.3 0.0 4.8e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Fungal_trans PF04082.13 CEP19411.1 - 1.5e-22 79.7 3.4 3.2e-22 78.6 2.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEP19411.1 - 1.8e-08 34.1 7.4 4.8e-08 32.7 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E2F_TDP PF02319.15 CEP19412.1 - 3.9e-23 80.7 0.2 7e-23 79.9 0.1 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain PPR_2 PF13041.1 CEP19413.1 - 7.8e-68 224.2 23.6 8.2e-12 44.9 0.0 17.3 13 2 5 18 18 17 14 PPR repeat family PPR_3 PF13812.1 CEP19413.1 - 2.5e-53 173.9 11.9 0.0035 17.5 0.0 19.3 20 0 0 20 20 19 12 Pentatricopeptide repeat domain PPR PF01535.15 CEP19413.1 - 3.5e-50 164.5 15.1 0.00053 19.7 0.0 19.9 21 1 1 22 22 21 11 PPR repeat PPR_1 PF12854.2 CEP19413.1 - 2.4e-20 71.6 16.9 0.049 13.1 0.0 14.8 18 0 0 18 18 17 5 PPR repeat TPR_14 PF13428.1 CEP19413.1 - 2.4e-12 46.3 0.0 12 6.8 0.0 10.9 9 2 2 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.1 CEP19413.1 - 3.5e-12 46.4 5.1 0.25 11.7 0.0 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP19413.1 - 3.4e-07 30.7 0.1 5.1 7.8 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEP19413.1 - 2.7e-06 26.7 4.2 1.9 8.4 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat ATP13 PF12921.2 CEP19413.1 - 7e-06 25.4 7.0 2.6 7.3 0.0 7.9 7 2 1 9 9 9 1 Mitochondrial ATPase expression TPR_2 PF07719.12 CEP19413.1 - 1.8e-05 24.3 8.5 11 6.1 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEP19413.1 - 0.00081 19.2 19.8 10 6.1 0.1 8.2 6 4 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP19413.1 - 0.0011 19.2 13.0 1.6 9.3 0.0 8.4 10 0 0 10 10 9 1 Tetratricopeptide repeat RPM2 PF08579.6 CEP19413.1 - 0.0035 17.4 8.7 0.15 12.1 0.0 5.8 6 2 1 7 7 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_11 PF13414.1 CEP19413.1 - 0.0047 16.5 12.5 5.2 6.7 0.0 6.8 6 1 0 6 6 6 1 TPR repeat Mic1 PF07035.7 CEP19413.1 - 0.04 13.2 0.5 3.6 6.9 0.0 3.4 3 0 0 3 3 3 0 Colon cancer-associated protein Mic1-like TPR_8 PF13181.1 CEP19413.1 - 0.058 13.2 21.9 8.6 6.3 0.1 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Clr5 PF14420.1 CEP19413.1 - 0.097 12.5 0.0 0.39 10.6 0.0 2.1 1 0 0 1 1 1 0 Clr5 domain TPR_1 PF00515.23 CEP19413.1 - 0.16 11.5 9.9 19 5.0 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.12 CEP19413.1 - 0.53 10.5 3.1 88 3.3 0.0 5.2 6 0 0 6 6 5 0 Bacterial transcriptional activator domain HOOK PF05622.7 CEP19414.1 - 3.2e-51 174.0 84.0 7.5e-48 162.8 39.3 2.5 1 1 1 2 2 2 2 HOOK protein PAC2 PF09754.4 CEP19414.1 - 0.73 9.6 8.7 0.1 12.4 0.1 2.8 3 0 0 3 3 3 0 PAC2 family CNH PF00780.17 CEP19415.1 - 2.3e-55 187.9 0.5 2e-54 184.8 0.3 2.2 1 1 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEP19415.1 - 7e-37 127.0 2.1 1.6e-36 125.8 1.5 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 CEP19415.1 - 3.7e-34 117.5 0.0 3.7e-34 117.5 0.0 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain DEP PF00610.16 CEP19415.1 - 6.6e-15 54.6 0.1 3.3e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HSP70 PF00012.15 CEP19416.1 - 0.0016 16.4 0.0 0.013 13.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Proteasome PF00227.21 CEP19417.1 - 4.4e-63 211.9 0.2 6.1e-63 211.5 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEP19417.1 - 5.7e-14 51.1 0.1 1e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature YqzH PF14164.1 CEP19417.1 - 0.28 11.1 3.1 1 9.2 0.5 2.7 2 1 1 3 3 3 0 YqzH-like protein DUF4284 PF14112.1 CEP19418.1 - 0.096 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) Pex2_Pex12 PF04757.9 CEP19419.1 - 2e-36 125.5 1.8 2.7e-36 125.1 1.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CEP19419.1 - 3.7e-10 39.4 13.7 7.7e-10 38.4 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEP19419.1 - 8.2e-09 35.0 11.1 1.3e-08 34.4 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP19419.1 - 1.1e-08 34.9 13.6 1.8e-08 34.2 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEP19419.1 - 4.4e-08 32.6 13.6 7.4e-08 31.9 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEP19419.1 - 2.9e-05 23.7 11.6 5e-05 22.9 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CEP19419.1 - 0.00016 21.7 6.9 0.00035 20.6 4.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger PAXIP1_C PF15364.1 CEP19419.1 - 0.0047 16.8 0.3 0.0083 16.0 0.2 1.3 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein zf-C3HC4_4 PF15227.1 CEP19419.1 - 0.015 15.1 12.9 0.034 14.0 8.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEP19419.1 - 0.026 14.2 9.3 0.066 12.9 6.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 CEP19419.1 - 0.032 13.9 5.1 0.062 13.0 3.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein NPIP PF06409.6 CEP19419.1 - 0.12 11.1 0.1 0.2 10.3 0.1 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Prok-RING_4 PF14447.1 CEP19419.1 - 0.36 10.4 10.0 1 8.9 6.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 CEP19419.1 - 2 8.3 8.6 1.6 8.6 4.6 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ytp1 PF10355.4 CEP19420.1 - 6.6e-90 300.9 13.6 6.6e-90 300.9 9.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CEP19420.1 - 1.1e-25 89.1 5.9 1.1e-25 89.1 4.1 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 CEP19420.1 - 0.47 10.2 37.9 0.092 12.5 8.6 4.7 4 2 0 4 4 4 0 Eukaryotic cytochrome b561 HAD PF12710.2 CEP19421.1 - 1.8e-20 73.9 0.7 7.9e-20 71.8 0.4 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEP19421.1 - 6.7e-18 64.5 0.2 1.1e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEP19421.1 - 6e-17 62.7 0.0 3.1e-16 60.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP19421.1 - 1.3e-11 44.2 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEP19421.1 - 0.0006 19.4 0.0 0.0051 16.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEP19421.1 - 0.051 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ILVD_EDD PF00920.16 CEP19422.1 - 1.3e-206 687.1 0.4 1.5e-206 686.8 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family DDE_3 PF13358.1 CEP19424.1 - 7.1e-26 90.7 0.0 1.1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 CEP19424.1 - 0.0064 15.2 0.0 0.0094 14.7 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain HTH_29 PF13551.1 CEP19425.1 - 0.00047 20.2 0.0 0.00097 19.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Carot_N PF09150.5 CEP19425.1 - 0.036 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal amfpi-1 PF12190.3 CEP19425.1 - 0.046 14.2 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protease inhibitor MIR PF02815.14 CEP19426.1 - 1.6e-18 66.9 1.1 3.7e-15 55.9 0.3 2.7 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.6 CEP19426.1 - 3.5e-11 42.5 0.2 6.8e-07 28.5 0.0 2.0 2 0 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.1 CEP19426.1 - 0.0062 16.8 1.4 2.5 8.5 0.7 2.7 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CEP19426.1 - 0.047 13.7 2.2 0.052 13.5 0.5 1.7 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain RAP1 PF07218.6 CEP19427.1 - 0.0082 14.3 0.2 0.0091 14.1 0.1 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) KaiC PF06745.8 CEP19427.1 - 0.0093 15.0 0.5 0.0095 15.0 0.4 1.1 1 0 0 1 1 1 1 KaiC Sec2p PF06428.6 CEP19427.1 - 0.095 12.5 2.4 0.15 11.9 1.6 1.4 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DHHW PF14286.1 CEP19427.1 - 0.12 11.6 1.0 0.13 11.5 0.7 1.0 1 0 0 1 1 1 0 DHHW protein DUF3450 PF11932.3 CEP19427.1 - 0.24 10.6 4.0 0.26 10.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FAR1 PF03101.10 CEP19428.1 - 5.1e-06 26.9 0.1 8.2e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain HLH PF00010.21 CEP19430.1 - 2.3e-18 65.6 0.2 2.3e-18 65.6 0.2 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain bZIP_2 PF07716.10 CEP19433.1 - 9.7e-13 47.7 7.6 9.7e-13 47.7 5.3 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CEP19433.1 - 1.3e-12 47.4 11.1 1.3e-12 47.4 7.7 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 CEP19433.1 - 0.00023 21.3 9.0 0.00041 20.5 5.8 1.8 1 1 0 1 1 1 1 bZIP Maf transcription factor Herpes_BLRF2 PF05812.7 CEP19433.1 - 0.0073 16.1 2.3 0.031 14.0 1.6 2.1 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein CENP-Q PF13094.1 CEP19433.1 - 0.049 13.6 6.0 0.092 12.7 4.2 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_UL6 PF01763.11 CEP19433.1 - 0.061 11.4 2.9 0.076 11.1 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CortBP2 PF09727.4 CEP19433.1 - 0.062 12.8 7.1 0.11 12.0 4.9 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 HALZ PF02183.13 CEP19433.1 - 0.12 12.0 7.7 0.15 11.8 0.3 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper TSC22 PF01166.13 CEP19433.1 - 0.16 11.9 2.1 0.18 11.8 0.4 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF972 PF06156.8 CEP19433.1 - 0.25 11.7 6.0 0.14 12.5 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4094 PF13334.1 CEP19433.1 - 0.28 11.6 3.1 0.37 11.1 1.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) O-FucT PF10250.4 CEP19434.1 - 2.2e-12 46.7 0.8 1.6e-10 40.6 0.5 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase WD40 PF00400.27 CEP19435.1 - 4.4e-12 45.3 0.4 0.56 10.1 0.0 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat ABC_tran PF00005.22 CEP19436.1 - 8.4e-45 152.4 3.1 3.9e-24 85.5 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CEP19436.1 - 3.7e-16 59.9 10.8 4.9e-05 23.4 0.0 5.1 4 1 1 5 5 5 4 AAA domain DUF258 PF03193.11 CEP19436.1 - 1.5e-10 40.4 0.1 0.0001 21.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 CEP19436.1 - 7.7e-10 38.3 9.1 0.0021 17.3 0.2 4.0 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CEP19436.1 - 1.4e-06 28.4 0.0 0.0075 16.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CEP19436.1 - 2e-06 27.7 0.9 0.0062 16.4 0.0 3.9 4 1 0 4 4 2 2 50S ribosome-binding GTPase NACHT PF05729.7 CEP19436.1 - 3e-06 26.9 0.0 0.038 13.6 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 CEP19436.1 - 3.4e-06 27.8 0.0 0.2 12.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain ABC_tran_2 PF12848.2 CEP19436.1 - 3.8e-06 26.6 9.8 3.8e-06 26.6 6.8 2.1 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.1 CEP19436.1 - 5.2e-06 25.8 0.0 0.019 14.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CEP19436.1 - 6.5e-06 26.2 0.9 0.19 11.7 0.1 3.7 2 2 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.17 CEP19436.1 - 6.6e-06 26.2 0.0 0.27 11.4 0.0 3.2 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.1 CEP19436.1 - 7.9e-06 25.7 0.2 1.2 9.0 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA PF00004.24 CEP19436.1 - 1.8e-05 24.9 0.0 0.16 12.1 0.0 3.4 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CEP19436.1 - 9.8e-05 22.2 6.3 0.2 11.5 0.0 4.0 4 1 0 4 4 3 2 AAA domain DAP3 PF10236.4 CEP19436.1 - 0.0001 21.3 8.2 0.014 14.3 0.0 3.8 4 0 0 4 4 4 2 Mitochondrial ribosomal death-associated protein 3 Miro PF08477.8 CEP19436.1 - 0.00015 22.2 0.3 0.16 12.5 0.0 3.4 3 0 0 3 3 3 1 Miro-like protein AAA_10 PF12846.2 CEP19436.1 - 0.00027 20.4 3.2 0.35 10.2 0.0 3.0 2 1 0 2 2 2 2 AAA-like domain AAA_28 PF13521.1 CEP19436.1 - 0.0005 20.0 0.0 0.01 15.7 0.0 2.9 2 1 0 3 3 2 1 AAA domain AAA_25 PF13481.1 CEP19436.1 - 0.0033 16.8 0.0 1.2 8.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain FeoB_N PF02421.13 CEP19436.1 - 0.0034 16.6 2.7 0.061 12.5 0.1 3.3 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_5 PF07728.9 CEP19436.1 - 0.0059 16.3 0.1 3.7 7.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 CEP19436.1 - 0.0063 16.2 0.1 0.95 9.1 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CEP19436.1 - 0.011 16.0 2.6 0.96 9.7 0.0 3.7 3 2 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 CEP19436.1 - 0.015 15.1 0.1 2.2 8.2 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CEP19436.1 - 0.017 15.4 0.0 0.017 15.4 0.0 4.1 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.4 CEP19436.1 - 0.03 13.8 0.2 0.72 9.3 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CEP19436.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.7 4 1 1 5 5 5 0 Dynamin family ABC2_membrane PF01061.19 CEP19437.1 - 2.6e-87 291.3 53.6 1.6e-47 161.4 12.1 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 CEP19437.1 - 1.7e-37 128.7 0.0 6.7e-20 71.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CEP19437.1 - 2.6e-30 104.0 1.7 1.1e-22 79.6 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CEP19437.1 - 1.5e-09 37.8 0.1 3.8e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CEP19437.1 - 8.8e-08 31.5 53.0 0.00093 18.3 17.3 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 CEP19437.1 - 7.7e-06 25.3 0.9 0.0094 15.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CEP19437.1 - 8.5e-06 25.9 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CEP19437.1 - 0.00018 21.6 0.0 0.051 13.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CEP19437.1 - 0.00023 20.3 0.1 0.0053 15.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CEP19437.1 - 0.0005 19.5 0.0 0.0075 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEP19437.1 - 0.0057 16.9 0.6 0.76 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CEP19437.1 - 0.012 15.5 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 CEP19437.1 - 0.02 14.3 0.2 0.17 11.3 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CEP19437.1 - 0.026 14.4 0.0 12 5.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CEP19437.1 - 0.037 14.8 0.2 0.71 10.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 CEP19437.1 - 0.055 13.9 0.0 4.5 7.8 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 CEP19437.1 - 0.096 12.3 0.6 0.66 9.6 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CEP19437.1 - 0.11 12.1 0.9 5.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase AAA_33 PF13671.1 CEP19437.1 - 0.18 11.7 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CEP19437.1 - 0.19 11.6 0.4 0.53 10.2 0.3 1.8 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CEP19437.1 - 0.21 11.0 0.2 1.3 8.5 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 CEP19437.1 - 0.27 10.9 0.9 8 6.2 0.3 2.6 2 0 0 2 2 2 0 Part of AAA domain PDR_assoc PF08370.6 CEP19437.1 - 3.4 7.2 9.4 0.22 11.0 0.3 3.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DUF2422 PF10337.4 CEP19438.1 - 3.2e-14 52.6 17.7 2.3e-12 46.4 12.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CEP19438.1 - 3.4e-14 52.8 14.2 3.4e-14 52.8 9.8 3.7 3 1 1 4 4 4 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 CEP19438.1 - 1.9e-13 50.5 0.0 3.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 CEP19438.1 - 7.4e-09 34.7 19.5 7.4e-07 28.1 1.4 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 CEP19438.1 - 3.3e-08 32.4 3.4 3.3e-08 32.4 2.3 2.7 3 0 0 3 3 3 1 Fusaric acid resistance protein family AMP-binding PF00501.23 CEP19439.1 - 4.5e-94 315.2 0.0 1.2e-93 313.8 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP19439.1 - 1.4e-12 48.4 0.1 3.2e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 CEP19440.1 - 3.2e-87 292.6 0.0 4.1e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEP19440.1 - 3e-10 40.8 0.0 8.2e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E1-E2_ATPase PF00122.15 CEP19441.1 - 7.7e-59 198.5 0.3 7.7e-59 198.5 0.2 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CEP19441.1 - 6.1e-21 75.8 0.0 1.7e-20 74.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP19441.1 - 4.4e-13 48.4 0.0 1.3e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEP19441.1 - 2e-12 47.6 0.0 4.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEP19441.1 - 0.00011 21.9 2.9 0.00011 21.8 0.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase SWIRM PF04433.12 CEP19442.1 - 9.5e-20 70.5 0.2 7.3e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 CEP19442.1 - 6.5e-13 48.5 0.5 6.5e-13 48.5 0.4 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain JAB PF01398.16 CEP19442.1 - 4.6e-12 45.6 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-bind_6 PF13921.1 CEP19442.1 - 3e-09 36.8 0.3 3e-08 33.6 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Prok-JAB PF14464.1 CEP19442.1 - 3.3e-09 36.2 0.2 6.8e-08 32.0 0.1 2.5 1 1 1 2 2 2 1 Prokaryotic homologs of the JAB domain NDT80_PhoG PF05224.7 CEP19443.1 - 2.9e-37 128.4 5.0 4.4e-37 127.8 0.0 2.8 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DAHP_synth_2 PF01474.11 CEP19444.1 - 5.4e-196 651.1 0.0 6.1e-196 651.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Lipase_GDSL PF00657.17 CEP19445.1 - 3.1e-08 33.7 0.1 9.2e-08 32.1 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEP19445.1 - 6.7e-07 29.6 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_16 PF10294.4 CEP19446.1 - 1.5e-31 109.1 0.0 2.2e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CEP19446.1 - 0.00073 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP19446.1 - 0.0083 16.6 0.0 0.034 14.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP19446.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEP19446.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 CEP19446.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 CEP19446.1 - 0.064 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.1 CEP19446.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SAICAR_synt PF01259.13 CEP19448.1 - 9.8e-94 313.0 0.2 1.2e-93 312.8 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase zf-C2H2 PF00096.21 CEP19449.1 - 1.4e-12 47.1 21.2 4.3e-06 26.7 2.1 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP19449.1 - 2.2e-10 40.2 9.8 0.00089 19.4 0.2 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP19449.1 - 4.4e-08 32.9 15.6 0.037 14.3 1.7 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger ROS_MUCR PF05443.6 CEP19449.1 - 0.043 13.5 3.0 0.081 12.6 2.1 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein zf-met PF12874.2 CEP19449.1 - 0.18 12.0 4.0 4.4 7.6 0.6 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP19449.1 - 1.2 9.3 14.0 2.3 8.4 0.7 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding RRN3 PF05327.6 CEP19450.1 - 1.4e-148 495.5 14.7 1.4e-148 495.5 10.2 1.7 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 CBF PF03914.12 CEP19450.1 - 0.048 13.1 1.7 0.07 12.5 0.0 2.1 2 0 0 2 2 2 0 CBF/Mak21 family Nop14 PF04147.7 CEP19450.1 - 5.1 4.8 12.8 0.56 8.0 0.1 2.3 2 0 0 2 2 2 0 Nop14-like family Pkinase PF00069.20 CEP19451.1 - 9.3e-53 179.0 0.0 1.6e-52 178.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19451.1 - 2.5e-21 75.9 0.0 4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19451.1 - 3.8e-06 26.0 0.0 1.4e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PAS_9 PF13426.1 CEP19451.1 - 3.7e-05 24.0 0.1 0.21 11.9 0.0 3.7 3 1 0 3 3 3 2 PAS domain APH PF01636.18 CEP19451.1 - 0.0005 19.8 0.3 0.018 14.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CEP19451.1 - 0.0077 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NuA4 PF09340.5 CEP19451.1 - 0.44 10.2 3.6 25 4.5 1.3 2.6 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 TPR_11 PF13414.1 CEP19452.1 - 1.1e-08 34.6 9.5 0.0066 16.0 0.9 3.9 2 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.1 CEP19452.1 - 2.9e-08 33.6 1.4 0.28 11.9 0.1 4.2 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CEP19452.1 - 1.7e-07 30.6 11.0 0.04 13.8 0.4 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP19452.1 - 1.9e-07 31.5 1.3 0.056 14.1 0.1 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP19452.1 - 1.8e-05 24.9 5.4 0.093 13.0 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEP19452.1 - 4.9e-05 22.8 7.9 0.52 10.2 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEP19452.1 - 0.0017 18.1 3.6 0.014 15.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEP19452.1 - 0.0018 17.7 9.4 0.49 10.0 0.8 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEP19452.1 - 0.018 14.9 7.7 1.3 9.0 0.9 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CEP19452.1 - 0.096 12.8 11.7 2.3 8.4 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CEP19452.1 - 0.097 12.9 1.3 6.6 7.1 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Urocanase PF01175.13 CEP19452.1 - 0.16 10.0 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Urocanase TPR_6 PF13174.1 CEP19452.1 - 2.7 8.6 6.6 4.5 7.9 0.1 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat AA_kinase PF00696.23 CEP19453.1 - 8.6e-37 126.9 0.0 1.1e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family Neuropeptide_S PF14993.1 CEP19454.1 - 0.092 12.4 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Neuropeptide S precursor protein Sel1 PF08238.7 CEP19455.1 - 3.4e-24 84.7 19.9 6.5e-07 29.7 0.0 8.3 8 0 0 8 8 8 6 Sel1 repeat TPR_17 PF13431.1 CEP19455.1 - 1.1 9.6 6.0 53 4.3 0.0 5.1 5 1 2 7 7 7 0 Tetratricopeptide repeat NUDIX PF00293.23 CEP19456.1 - 2.8e-08 33.4 0.0 4.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N PF00107.21 CEP19457.1 - 9.4e-15 54.3 0.2 2.5e-13 49.7 0.1 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP19457.1 - 0.014 16.3 0.0 0.034 15.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase La PF05383.12 CEP19458.1 - 1.7e-21 75.7 0.4 4e-21 74.5 0.3 1.7 1 0 0 1 1 1 1 La domain SRF-TF PF00319.13 CEP19459.1 - 1.7e-22 78.3 0.2 3e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Macoilin PF09726.4 CEP19459.1 - 3.2 5.9 7.0 4.3 5.5 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FRG1 PF06229.7 CEP19460.1 - 8.6e-24 84.0 2.9 4.2e-23 81.8 0.0 2.3 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 CEP19460.1 - 0.00053 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Fascin domain DUF4243 PF14027.1 CEP19461.1 - 4.2e-21 75.7 0.0 7.4e-21 74.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) SWIRM PF04433.12 CEP19462.1 - 5.1e-16 58.5 0.2 3e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 CEP19462.1 - 2.1e-09 36.7 7.6 3.8e-09 35.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CEP19462.1 - 5.8e-08 32.6 0.0 1.9e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain HEAT_2 PF13646.1 CEP19463.1 - 9.9e-08 32.1 0.6 0.00018 21.7 0.0 5.0 5 1 1 6 6 6 1 HEAT repeats HEAT PF02985.17 CEP19463.1 - 7.2e-05 22.5 0.0 0.061 13.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CEP19463.1 - 0.00012 22.4 0.0 0.019 15.4 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat TPR_12 PF13424.1 CEP19464.1 - 1.1e-17 63.7 25.3 5.8e-06 26.1 2.3 3.9 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 CEP19464.1 - 1.8e-12 46.0 6.0 0.00032 20.2 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 CEP19464.1 - 1.5e-09 37.3 12.5 4.5e-05 22.9 0.2 4.0 2 2 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 CEP19464.1 - 3e-09 36.0 12.7 0.0015 18.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEP19464.1 - 1.1e-08 34.2 12.0 4.2e-05 22.9 0.1 4.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEP19464.1 - 1.5e-08 33.8 4.8 0.01 15.5 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEP19464.1 - 2.1e-06 28.2 11.3 0.00098 19.7 3.6 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEP19464.1 - 2.1e-06 27.8 14.2 0.052 14.2 0.3 5.6 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEP19464.1 - 2.6e-06 27.1 10.6 0.061 13.2 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 CEP19464.1 - 8.5e-05 22.5 5.2 0.00091 19.1 0.6 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEP19464.1 - 0.00015 22.0 3.9 0.23 11.8 0.9 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 CEP19464.1 - 0.0042 16.9 4.8 0.037 13.8 0.2 3.5 3 1 1 4 4 3 1 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 CEP19464.1 - 0.011 15.1 0.3 0.39 10.0 0.1 2.5 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Apc3 PF12895.2 CEP19464.1 - 0.022 14.8 5.7 0.31 11.1 0.2 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CEP19464.1 - 0.22 11.8 2.8 12 6.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP19464.1 - 0.65 10.5 5.5 19 5.9 0.0 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat ELFV_dehydrog PF00208.16 CEP19465.1 - 3e-52 177.6 0.0 5.8e-52 176.7 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CEP19465.1 - 2.5e-25 88.2 0.0 3e-18 64.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 CEP19465.1 - 0.046 13.3 0.0 0.16 11.5 0.0 2.0 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain polyprenyl_synt PF00348.12 CEP19466.1 - 8.8e-79 264.0 0.0 1e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase NurA PF09376.5 CEP19467.1 - 0.006 16.1 0.2 0.0063 16.0 0.2 1.2 1 0 0 1 1 1 1 NurA domain NYN_YacP PF05991.6 CEP19467.1 - 0.0086 15.8 0.1 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 YacP-like NYN domain TrkA_N PF02254.13 CEP19467.1 - 0.031 14.2 1.2 0.087 12.8 0.4 2.0 1 1 1 2 2 2 0 TrkA-N domain DUF1426 PF07234.6 CEP19467.1 - 0.14 11.9 0.3 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) zf-CCHC PF00098.18 CEP19468.1 - 0.0041 16.9 0.3 0.0041 16.9 0.2 4.3 5 0 0 5 5 5 2 Zinc knuckle zf-C4_Topoisom PF01396.14 CEP19468.1 - 0.051 13.0 5.2 1.2 8.7 0.2 3.2 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_4 PF13717.1 CEP19468.1 - 0.083 12.6 4.6 2 8.2 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DUF164 PF02591.10 CEP19468.1 - 0.14 12.0 4.3 0.67 9.8 0.3 3.1 3 0 0 3 3 3 0 Putative zinc ribbon domain zinc_ribbon_5 PF13719.1 CEP19468.1 - 0.17 11.5 4.8 2.5 7.7 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-HYPF PF07503.7 CEP19468.1 - 0.18 11.2 2.1 5 6.6 0.0 3.2 3 0 0 3 3 3 0 HypF finger DZR PF12773.2 CEP19468.1 - 0.54 10.1 14.7 2 8.2 2.7 3.3 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CEP19468.1 - 0.84 9.2 8.9 0.68 9.4 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CEP19468.1 - 4 6.7 11.5 0.52 9.6 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain PHD PF00628.24 CEP19468.1 - 4.6 7.0 13.0 9.8 5.9 0.0 4.3 4 2 0 4 4 4 0 PHD-finger HypA PF01155.14 CEP19468.1 - 6.3 6.5 14.3 2.2 8.0 1.0 3.4 2 1 2 4 4 4 0 Hydrogenase expression/synthesis hypA family OSCP PF00213.13 CEP19469.1 - 8.8e-43 146.1 4.5 1.1e-42 145.8 3.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit vATP-synt_E PF01991.13 CEP19469.1 - 0.032 13.5 0.8 0.096 11.9 0.1 1.9 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit BRO1 PF03097.13 CEP19471.1 - 3.4e-22 78.7 1.6 4.5e-22 78.3 1.1 1.0 1 0 0 1 1 1 1 BRO1-like domain RrnaAD PF00398.15 CEP19472.1 - 2.1e-46 158.1 0.1 2.3e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CEP19472.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TauD PF02668.11 CEP19473.1 - 8.6e-54 182.9 0.1 1e-53 182.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Porphobil_deam PF01379.15 CEP19474.1 - 1.8e-77 259.0 0.2 1.1e-57 194.4 0.0 2.1 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CEP19474.1 - 3.8e-18 65.3 0.5 1e-17 64.0 0.3 1.8 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Dynamin_M PF01031.15 CEP19475.1 - 8.7e-109 362.8 0.1 2.6e-108 361.3 0.0 1.8 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.18 CEP19475.1 - 2.5e-56 190.1 0.1 5.9e-56 188.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CEP19475.1 - 9.8e-32 108.7 3.2 9.8e-32 108.7 2.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CEP19475.1 - 0.0018 18.1 0.1 0.0062 16.4 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CEP19475.1 - 0.04 14.4 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 CEP19475.1 - 0.097 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain F-box-like PF12937.2 CEP19476.1 - 4.7e-05 23.0 0.4 0.00013 21.6 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP19476.1 - 0.0046 16.5 0.4 0.02 14.5 0.3 2.2 1 0 0 1 1 1 1 F-box domain TOMM6 PF15184.1 CEP19476.1 - 0.061 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Clat_adaptor_s PF01217.15 CEP19476.1 - 0.08 12.6 1.0 0.14 11.9 0.2 1.7 2 0 0 2 2 2 0 Clathrin adaptor complex small chain Sugar_tr PF00083.19 CEP19477.1 - 1.7e-98 330.1 30.3 8.8e-51 172.8 3.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP19477.1 - 1.5e-25 89.6 41.4 4.1e-18 65.2 6.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP19477.1 - 0.00064 18.2 7.0 0.00064 18.2 4.8 3.5 2 2 2 4 4 4 2 MFS/sugar transport protein RabGAP-TBC PF00566.13 CEP19478.1 - 1.6e-57 194.4 0.3 1.6e-57 194.4 0.2 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ORF6N PF10543.4 CEP19478.1 - 0.0047 16.9 0.5 0.023 14.7 0.3 2.2 1 0 0 1 1 1 1 ORF6N domain Jnk-SapK_ap_N PF09744.4 CEP19478.1 - 0.036 14.0 22.1 0.43 10.5 8.0 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ComZ PF10815.3 CEP19478.1 - 0.036 13.8 0.1 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 ComZ HALZ PF02183.13 CEP19478.1 - 0.58 9.9 15.3 3.3 7.5 0.3 4.6 3 1 2 5 5 5 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 CEP19478.1 - 0.96 9.3 28.7 0.3 10.9 15.5 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CEP19478.1 - 5 6.0 23.6 2.4 7.1 13.8 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 CEP19478.1 - 5.2 6.6 31.0 0.77 9.3 9.1 3.2 3 0 0 3 3 3 0 IncA protein Lipase_3 PF01764.20 CEP19479.1 - 2.2e-09 37.0 0.0 4.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CEP19479.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CEP19479.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 CEP19479.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2048 PF09752.4 CEP19479.1 - 0.16 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Zn_clus PF00172.13 CEP19480.1 - 1e-06 28.5 10.4 1e-06 28.5 7.2 2.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLP_protease PF00574.18 CEP19481.1 - 1.9e-80 268.8 0.0 2.3e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease SurA_N_3 PF13624.1 CEP19481.1 - 0.098 12.6 0.2 0.59 10.1 0.1 1.9 2 0 0 2 2 2 0 SurA N-terminal domain Iso_dh PF00180.15 CEP19482.1 - 2.5e-77 260.1 0.0 3.2e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IBN_N PF03810.14 CEP19483.1 - 2e-14 53.2 0.0 3.7e-12 45.9 0.0 3.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CEP19483.1 - 9.8e-05 22.3 1.4 0.00035 20.5 0.1 2.7 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 CEP19483.1 - 0.003 17.7 1.3 0.045 14.0 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats Nse4_C PF08743.5 CEP19484.1 - 1.3e-22 79.5 0.2 1.3e-22 79.5 0.2 2.7 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CEP19484.1 - 0.00043 20.0 0.0 0.00094 18.9 0.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE ABC1 PF03109.11 CEP19485.1 - 8.3e-34 116.1 0.0 1.4e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Oxidored_q1_N PF00662.15 CEP19485.1 - 0.26 10.8 1.5 0.37 10.3 0.4 1.7 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus SART-1 PF03343.8 CEP19486.1 - 1.9e-110 370.0 83.9 1e-109 367.6 58.2 1.9 1 1 0 1 1 1 1 SART-1 family Chitin_synth_2 PF03142.10 CEP19487.1 - 7.3e-243 806.7 0.1 1.1e-242 806.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEP19487.1 - 3.6e-130 435.1 2.1 4.8e-130 434.7 1.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 CEP19487.1 - 1.3e-20 72.9 0.1 1.9e-14 53.1 0.1 3.0 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 CEP19487.1 - 7e-19 67.3 0.4 1.4e-17 63.1 0.4 3.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 CEP19487.1 - 2.3e-15 56.8 1.7 7.9e-15 55.0 1.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP19487.1 - 1.6e-14 54.2 0.0 3e-11 43.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEP19487.1 - 1.9e-05 24.4 0.0 0.0014 18.3 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP19487.1 - 0.0075 15.5 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 AAA_29 PF13555.1 CEP19487.1 - 0.023 14.2 0.0 0.071 12.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flu_B_M2 PF04772.7 CEP19488.1 - 0.066 13.2 0.6 0.092 12.8 0.4 1.2 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) KAR9 PF08580.5 CEP19489.1 - 5.3e-06 25.0 0.6 5.3e-06 25.0 0.4 3.5 3 1 0 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.12 CEP19489.1 - 0.0007 19.3 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF4164 PF13747.1 CEP19489.1 - 0.016 15.3 1.8 17 5.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) HALZ PF02183.13 CEP19489.1 - 0.059 13.0 0.2 0.25 11.0 0.1 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper PMC2NT PF08066.7 CEP19489.1 - 2.1 8.7 9.2 12 6.3 0.0 4.7 4 1 1 5 5 5 0 PMC2NT (NUC016) domain SMP PF04927.7 CEP19490.1 - 0.028 14.4 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Seed maturation protein fn3_3 PF14686.1 CEP19490.1 - 2.4 8.3 8.9 1.6 8.9 4.0 2.4 2 1 0 2 2 2 0 Polysaccharide lyase family 4, domain II SIR2 PF02146.12 CEP19491.1 - 1.6e-61 207.1 0.0 2.6e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 CEP19491.1 - 0.0026 17.3 0.2 0.006 16.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF592) p450 PF00067.17 CEP19492.1 - 5.1e-79 265.9 0.0 6e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHD5 PF04420.9 CEP19493.1 - 9.7e-43 145.6 2.4 1.2e-42 145.3 1.6 1.1 1 0 0 1 1 1 1 CHD5-like protein LCD1 PF09798.4 CEP19493.1 - 0.027 12.5 0.6 0.033 12.2 0.4 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DASH_Duo1 PF08651.5 CEP19494.1 - 0.062 12.8 4.4 2.6 7.7 0.0 3.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 FAD-oxidase_C PF02913.14 CEP19495.1 - 2.8e-55 187.3 0.0 3.9e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CEP19495.1 - 6.8e-37 126.0 0.5 1.4e-36 125.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Glyco_transf_20 PF00982.16 CEP19496.1 - 1.1e-162 541.8 0.0 1.4e-162 541.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEP19496.1 - 2.9e-76 255.4 0.0 2.8e-75 252.2 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CEP19496.1 - 3.1e-05 23.6 0.0 0.0099 15.4 0.1 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEP19496.1 - 0.0022 18.1 0.0 0.04 14.0 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Chitin_synth_2 PF03142.10 CEP19497.1 - 7.7e-274 908.9 2.0 1.1e-273 908.5 1.4 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP19497.1 - 6.7e-17 61.8 1.5 6.7e-17 61.8 1.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP19497.1 - 1.6e-16 60.7 0.0 9e-15 55.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CEP19497.1 - 1.4e-08 34.3 0.0 8.3e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 CEP19497.1 - 0.00015 21.0 0.1 0.04 13.2 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CEP19497.1 - 0.00045 19.9 0.0 0.092 12.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 HAD PF12710.2 CEP19498.1 - 3e-12 47.1 0.1 7.2e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SPX PF03105.14 CEP19498.1 - 1.8e-11 44.3 10.6 6.2e-08 32.7 0.1 2.8 2 1 1 3 3 3 2 SPX domain Hydrolase_3 PF08282.7 CEP19498.1 - 1.7e-09 37.6 2.3 7.6e-09 35.5 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEP19498.1 - 4.2e-08 33.8 0.7 5.8e-07 30.1 0.5 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.1 CEP19498.1 - 3.8e-07 29.7 0.0 1.3e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 ACT domain Put_Phosphatase PF06888.7 CEP19498.1 - 0.00091 18.4 0.0 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.1 CEP19498.1 - 0.011 15.9 0.0 0.035 14.3 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 CEP19498.1 - 0.053 12.4 0.1 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF705) SelR PF01641.13 CEP19499.1 - 9.2e-53 177.1 0.3 1e-52 177.0 0.2 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 CEP19499.1 - 0.014 15.0 1.2 0.069 12.9 0.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 CEP19499.1 - 0.33 11.0 3.5 2.5 8.2 2.4 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PapD-like PF14874.1 CEP19501.1 - 4.4e-08 32.9 0.0 0.13 12.2 0.0 4.5 5 0 0 5 5 5 3 Flagellar-associated PapD-like Polysacc_deac_1 PF01522.16 CEP19502.1 - 1.6e-23 82.7 0.1 2.9e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP19502.1 - 0.027 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF3806 PF12713.2 CEP19503.1 - 0.066 12.6 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) p450 PF00067.17 CEP19504.1 - 1.6e-78 264.2 0.0 2.4e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.18 CEP19505.1 - 3.4e-09 35.9 0.3 1.2e-08 34.1 0.1 1.9 1 1 0 2 2 2 1 SNF2 family N-terminal domain zf-GRF PF06839.7 CEP19505.1 - 5.6e-05 22.9 7.6 0.00011 21.9 5.2 1.6 1 0 0 1 1 1 1 GRF zinc finger RdRP PF05183.7 CEP19506.1 - 1.2e-112 377.5 0.3 1.9e-112 376.9 0.2 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sporozoite_P67 PF05642.6 CEP19506.1 - 0.61 7.8 4.0 0.93 7.2 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 CEP19506.1 - 1.4 9.2 4.6 3.6 7.9 3.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tropomyosin_1 PF12718.2 CEP19507.1 - 0.00016 21.5 27.0 0.034 13.9 0.7 3.4 3 1 0 3 3 3 3 Tropomyosin like LOH1CR12 PF10158.4 CEP19507.1 - 0.0038 17.0 2.3 0.0038 17.0 1.6 2.8 2 1 0 3 3 3 1 Tumour suppressor protein PilJ PF13675.1 CEP19507.1 - 0.011 16.0 3.4 0.28 11.5 0.1 3.1 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Snapin_Pallidin PF14712.1 CEP19507.1 - 0.02 15.1 19.5 0.15 12.3 2.1 3.5 3 0 0 3 3 3 0 Snapin/Pallidin BLOC1_2 PF10046.4 CEP19507.1 - 0.023 14.8 2.5 0.023 14.8 1.7 3.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COP23 PF14218.1 CEP19507.1 - 0.03 13.8 0.2 0.084 12.4 0.1 1.7 1 0 0 1 1 1 0 Circadian oscillating protein COP23 NPV_P10 PF05531.7 CEP19507.1 - 0.043 14.0 8.2 0.92 9.8 0.2 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HPPK PF01288.15 CEP19507.1 - 0.12 12.1 2.3 0.21 11.3 0.3 2.5 1 1 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Reo_sigmaC PF04582.7 CEP19507.1 - 0.17 11.0 11.7 0.12 11.5 2.5 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Jnk-SapK_ap_N PF09744.4 CEP19507.1 - 0.26 11.2 25.8 2.1 8.3 3.1 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Tropomyosin PF00261.15 CEP19507.1 - 0.28 10.2 26.5 1 8.4 2.7 3.5 1 1 3 4 4 4 0 Tropomyosin DUF1664 PF07889.7 CEP19507.1 - 0.28 10.9 20.0 0.19 11.5 3.5 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 CEP19507.1 - 0.29 10.9 32.2 0.12 12.2 3.2 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 CEP19507.1 - 0.37 10.8 24.8 2 8.4 2.8 3.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PSI_PsaF PF02507.10 CEP19507.1 - 0.54 9.7 8.6 1.4 8.4 0.1 2.6 3 0 0 3 3 3 0 Photosystem I reaction centre subunit III MerR-DNA-bind PF09278.6 CEP19507.1 - 0.63 10.4 3.4 7.3 7.0 0.1 3.5 2 2 1 3 3 3 0 MerR, DNA binding Adeno_PIX PF03955.9 CEP19507.1 - 1 9.9 12.8 0.54 10.8 0.6 3.3 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) TMF_DNA_bd PF12329.3 CEP19507.1 - 1.3 8.9 28.2 0.63 9.8 3.1 4.0 3 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 CEP19507.1 - 1.7 8.3 25.0 2.3 7.9 1.2 4.1 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Toxin_52 PF15605.1 CEP19507.1 - 2.2 8.2 10.7 1.2 9.0 0.4 3.1 3 0 0 3 3 3 0 Putative toxin 52 Fib_alpha PF08702.5 CEP19507.1 - 3.2 7.8 27.7 2.7 8.0 4.8 3.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.5 CEP19507.1 - 3.5 7.7 8.9 7.6 6.6 0.3 3.3 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Occludin_ELL PF07303.8 CEP19507.1 - 3.7 8.3 17.8 0.38 11.5 0.2 4.0 2 2 0 3 3 3 0 Occludin homology domain SlyX PF04102.7 CEP19507.1 - 3.9 7.9 15.3 0.66 10.3 0.2 4.0 3 2 2 5 5 5 0 SlyX Vac_Fusion PF02346.11 CEP19507.1 - 3.9 6.9 15.4 0.47 9.9 0.3 4.2 4 1 1 5 5 4 0 Chordopoxvirus fusion protein DivIC PF04977.10 CEP19507.1 - 5.5 6.5 17.4 1.2 8.6 0.8 4.0 3 1 1 4 4 4 0 Septum formation initiator DUF4164 PF13747.1 CEP19507.1 - 5.9 7.1 11.9 0.25 11.4 0.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) PTR2 PF00854.16 CEP19508.1 - 9.1e-58 195.8 20.6 3.4e-26 91.9 0.3 3.1 2 1 1 3 3 3 3 POT family MFS_1 PF07690.11 CEP19508.1 - 1e-11 44.1 21.8 3e-08 32.7 7.2 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily PTR2 PF00854.16 CEP19509.1 - 1.6e-57 194.9 19.1 4.3e-25 88.3 1.6 3.1 2 1 1 3 3 3 3 POT family Terminase_3 PF04466.8 CEP19509.1 - 0.17 10.9 0.8 0.26 10.3 0.6 1.2 1 0 0 1 1 1 0 Phage terminase large subunit YWFCY PF14293.1 CEP19509.1 - 0.59 10.0 3.7 19 5.2 1.8 3.5 3 1 1 4 4 4 0 YWFCY protein DUF2104 PF09877.4 CEP19509.1 - 0.71 9.8 5.3 0.18 11.7 0.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) PIF1 PF05970.9 CEP19510.1 - 8.9e-54 182.8 1.3 1.9e-43 148.8 0.1 3.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CEP19510.1 - 8.5e-18 64.6 0.0 1.7e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP19510.1 - 2.1e-06 27.9 0.0 5.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CEP19510.1 - 5.1e-05 22.3 0.1 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Herpes_Helicase PF02689.9 CEP19510.1 - 0.0001 20.2 0.2 0.089 10.5 0.0 2.2 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.1 CEP19510.1 - 0.0021 18.1 0.0 0.007 16.4 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CEP19510.1 - 0.0023 17.6 0.1 0.0058 16.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CEP19510.1 - 0.0027 16.7 0.0 0.0082 15.1 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 CEP19510.1 - 0.0034 17.3 0.2 0.019 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 CEP19510.1 - 0.0062 16.6 0.3 0.023 14.8 0.0 2.2 2 1 0 2 2 1 1 RNA helicase Helicase_RecD PF05127.9 CEP19510.1 - 0.0063 16.1 0.3 0.04 13.5 0.2 2.3 1 1 0 1 1 1 1 Helicase AAA PF00004.24 CEP19510.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CEP19510.1 - 0.016 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 CEP19510.1 - 0.019 13.6 0.1 0.037 12.6 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 CEP19510.1 - 0.02 14.3 3.1 1.5 8.2 0.0 3.2 3 1 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.9 CEP19510.1 - 0.021 14.5 0.0 0.055 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 CEP19510.1 - 0.033 13.4 0.0 0.088 12.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.13 CEP19510.1 - 0.033 13.7 3.9 0.65 9.4 0.1 3.5 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DDHD PF02862.12 CEP19510.1 - 0.035 13.9 11.0 0.072 12.8 7.5 1.5 1 1 0 1 1 1 0 DDHD domain Sigma54_activ_2 PF14532.1 CEP19510.1 - 0.036 14.1 0.0 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 CEP19510.1 - 0.036 13.2 0.1 0.085 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CEP19510.1 - 0.056 13.1 0.1 0.17 11.5 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CEP19510.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 CEP19510.1 - 0.061 13.2 0.1 0.31 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEP19510.1 - 0.078 13.2 0.1 0.078 13.2 0.0 2.8 2 1 1 3 3 2 0 ABC transporter ArgK PF03308.11 CEP19510.1 - 0.088 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_11 PF13086.1 CEP19510.1 - 0.16 11.5 6.7 3.5 7.1 0.0 3.6 2 1 1 4 4 3 0 AAA domain DUF3446 PF11928.3 CEP19512.1 - 1.5 9.0 11.6 0.51 10.5 6.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Pyr_redox_dim PF02852.17 CEP19513.1 - 5.4e-41 139.0 0.2 2.5e-40 136.9 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CEP19513.1 - 5e-39 134.2 14.8 3.1e-38 131.6 10.2 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP19513.1 - 4.3e-21 75.0 10.0 3e-18 65.9 0.8 3.8 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEP19513.1 - 3.7e-14 52.6 0.3 2.4e-11 43.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 CEP19513.1 - 4.7e-11 42.1 4.8 1.3e-09 37.4 0.8 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CEP19513.1 - 1.4e-09 37.3 13.9 4.6e-08 32.3 1.1 4.0 3 1 1 4 4 4 2 FAD binding domain Pyr_redox_3 PF13738.1 CEP19513.1 - 3.3e-09 37.0 4.5 0.00037 20.6 1.3 3.2 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEP19513.1 - 2.3e-08 33.9 3.2 9.4e-05 22.3 0.1 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CEP19513.1 - 2.5e-08 33.2 7.7 6.5e-07 28.6 0.7 2.8 1 1 1 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 CEP19513.1 - 5.3e-07 29.0 6.8 0.0094 15.0 0.3 3.3 3 0 0 3 3 3 3 FAD binding domain HI0933_like PF03486.9 CEP19513.1 - 1.4e-06 27.0 12.7 9.9e-06 24.2 0.5 3.9 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.19 CEP19513.1 - 2.5e-06 26.6 14.4 0.00043 19.3 0.1 3.5 3 1 1 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CEP19513.1 - 0.00021 20.9 3.2 0.0042 16.6 0.1 2.9 2 1 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CEP19513.1 - 0.00068 19.3 4.0 0.013 15.1 0.2 2.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 CEP19513.1 - 0.00073 18.5 0.2 0.63 8.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.9 CEP19513.1 - 0.0025 17.2 2.7 0.03 13.6 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 CEP19513.1 - 0.033 14.4 1.6 6.6 7.0 0.1 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 CEP19513.1 - 0.053 12.4 0.4 0.053 12.4 0.3 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein XdhC_C PF13478.1 CEP19513.1 - 0.097 12.9 0.0 5.8 7.2 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain HAD_2 PF13419.1 CEP19514.1 - 7.6e-18 65.3 0.0 1.4e-17 64.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEP19514.1 - 1e-07 31.5 0.1 1.7e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CEP19514.1 - 0.078 13.3 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.17 CEP19515.1 - 5.7e-92 308.4 0.0 6.4e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PIF1 PF05970.9 CEP19516.1 - 5.2e-76 255.9 0.2 3.5e-41 141.3 0.6 2.9 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CEP19516.1 - 8.6e-07 28.7 0.0 2e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP19516.1 - 6.8e-05 22.5 0.2 0.00017 21.2 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CEP19516.1 - 0.0092 15.5 0.0 0.041 13.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEP19516.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CEP19516.1 - 0.025 14.6 0.0 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CEP19516.1 - 0.033 12.8 0.0 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 CEP19516.1 - 0.053 12.4 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 CEP19516.1 - 0.072 12.0 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain T2SE PF00437.15 CEP19516.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Arginase PF00491.16 CEP19518.1 - 6.7e-77 258.4 0.0 8e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family HTH_32 PF13565.1 CEP19520.1 - 0.00087 20.0 0.0 0.00096 19.9 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CEP19520.1 - 0.0084 16.2 0.0 0.0087 16.1 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CEP19520.1 - 0.023 14.6 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 CEP19521.1 - 7.6e-15 54.9 0.1 1.5e-14 53.9 0.1 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Minor_capsid_1 PF10665.4 CEP19522.1 - 0.083 12.7 0.1 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein Calcipressin PF04847.7 CEP19523.1 - 0.043 13.3 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Calcipressin LSM PF01423.17 CEP19524.1 - 2.8e-17 62.0 1.4 4e-17 61.5 0.9 1.2 1 0 0 1 1 1 1 LSM domain UBX PF00789.15 CEP19525.1 - 4.7e-13 49.0 0.0 1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CEP19525.1 - 4.2e-07 29.3 0.1 7.9e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 CEP19525.1 - 5e-05 23.2 0.0 0.00031 20.7 0.0 2.4 1 0 0 1 1 1 1 Thioredoxin-like DUF1327 PF07041.6 CEP19525.1 - 0.11 12.3 0.5 0.29 11.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) AAA_23 PF13476.1 CEP19525.1 - 1.2 9.4 18.5 0.31 11.3 2.8 2.3 2 0 0 2 2 2 0 AAA domain DUF972 PF06156.8 CEP19525.1 - 2.5 8.4 14.2 0.12 12.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DDHD PF02862.12 CEP19525.1 - 3.5 7.3 9.8 1.2 8.9 1.2 2.1 2 0 0 2 2 2 0 DDHD domain MRP-S26 PF14943.1 CEP19525.1 - 5.1 6.6 21.4 7.8 6.0 10.2 2.6 2 1 0 2 2 2 0 Mitochondrial ribosome subunit S26 DHHA2 PF02833.9 CEP19526.1 - 4.6e-15 55.9 0.2 7.4e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CEP19526.1 - 3.4e-09 36.4 0.8 5.8e-09 35.7 0.1 1.7 2 0 0 2 2 2 1 DHH family F-box-like PF12937.2 CEP19526.1 - 1.3e-06 28.0 0.1 3.3e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP19526.1 - 0.00012 21.6 0.0 0.00043 19.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain Saccharop_dh_N PF04455.7 CEP19526.1 - 0.065 13.3 0.0 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region Ribosomal_S15 PF00312.17 CEP19527.1 - 4.6e-24 83.9 2.3 9.5e-24 82.9 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DnaI_N PF07319.6 CEP19527.1 - 0.014 15.6 0.9 1 9.6 0.0 2.7 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF1767 PF08585.7 CEP19528.1 - 0.00022 21.4 0.0 0.00045 20.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Cyt-b5 PF00173.23 CEP19529.1 - 2e-23 81.9 0.3 3.9e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TENA_THI-4 PF03070.11 CEP19529.1 - 5e-13 49.2 3.2 8.5e-12 45.2 2.2 2.1 1 1 0 1 1 1 1 TENA/THI-4/PQQC family DUF1193 PF06702.7 CEP19529.1 - 0.084 12.2 0.6 0.13 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1193) Polysacc_deac_1 PF01522.16 CEP19530.1 - 1e-27 96.2 0.0 1.8e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP19530.1 - 0.0099 14.8 0.0 0.022 13.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 zf-RVT PF13966.1 CEP19531.1 - 0.0038 17.5 0.8 0.0087 16.3 0.5 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Lactate_perm PF02652.9 CEP19532.1 - 7.8e-108 361.2 26.4 3.8e-62 210.4 8.0 2.1 2 0 0 2 2 2 2 L-lactate permease OrfB_Zn_ribbon PF07282.6 CEP19532.1 - 0.0061 16.2 0.2 0.016 14.8 0.2 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PIF1 PF05970.9 CEP19533.1 - 7e-10 38.3 0.1 8.4e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DUF4451 PF14616.1 CEP19534.1 - 0.12 12.1 0.8 0.2 11.4 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) zf-C2H2_4 PF13894.1 CEP19535.1 - 1.8e-06 27.8 11.9 0.0016 18.6 2.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEP19535.1 - 3.5e-06 27.0 7.1 3.5e-06 27.0 4.9 3.9 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.21 CEP19535.1 - 3.3e-05 23.9 15.2 0.0019 18.4 3.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type tRNA-synt_2 PF00152.15 CEP19536.1 - 1.6e-74 250.6 0.3 5.3e-74 248.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CEP19536.1 - 4.2e-10 39.3 0.0 8.4e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 CEP19536.1 - 0.034 13.6 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 tRNA_anti-like Ribosomal_L22 PF00237.14 CEP19536.1 - 0.73 9.7 4.1 8 6.4 2.6 2.5 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e Transformer PF06495.6 CEP19537.1 - 0.091 12.6 2.5 0.19 11.6 1.7 1.5 1 1 0 1 1 1 0 Fruit fly transformer protein PIF1 PF05970.9 CEP19538.1 - 2e-09 36.8 0.1 5.3e-09 35.4 0.0 1.6 1 1 1 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 CEP19538.1 - 6.2e-08 32.4 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEP19538.1 - 0.001 19.2 0.1 0.0022 18.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEP19538.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CEP19538.1 - 0.018 14.5 0.0 0.037 13.5 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 CEP19538.1 - 0.038 14.8 0.2 0.049 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CEP19538.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CEP19538.1 - 0.12 12.7 0.0 0.13 12.5 0.0 1.3 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 CEP19538.1 - 0.16 10.9 0.4 0.21 10.5 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Herpes_Helicase PF02689.9 CEP19539.1 - 0.00017 19.5 0.1 0.0002 19.2 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP19539.1 - 0.00071 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 CEP19539.1 - 0.01 14.7 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase ATP-grasp_2 PF08442.5 CEP19540.1 - 9.9e-77 256.8 0.0 2.1e-76 255.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CEP19540.1 - 7.9e-24 83.9 0.6 1.3e-23 83.2 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CEP19540.1 - 4.5e-08 32.5 0.1 1.1e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 CEP19540.1 - 0.0038 16.8 0.0 0.24 10.9 0.0 2.6 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TOBE_2 PF08402.5 CEP19540.1 - 0.0054 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 TOBE domain Flexi_CP PF00286.15 CEP19541.1 - 0.012 15.2 0.2 0.092 12.4 0.1 2.2 1 1 1 2 2 2 0 Viral coat protein zf-primase PF09329.6 CEP19542.1 - 4.2e-06 26.2 1.5 8.1e-06 25.3 1.1 1.5 1 0 0 1 1 1 1 Primase zinc finger Cyclin_N PF00134.18 CEP19543.1 - 0.00092 18.7 0.3 0.0025 17.3 0.2 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain CDC37_C PF08564.5 CEP19543.1 - 0.75 9.6 6.1 5.3 6.9 0.0 3.3 4 0 0 4 4 4 0 Cdc37 C terminal domain CLTH PF10607.4 CEP19544.1 - 7.5e-31 106.7 0.2 7.5e-31 106.7 0.1 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 CEP19544.1 - 3.3e-11 42.7 0.5 3.3e-11 42.7 0.3 2.3 2 0 0 2 2 2 1 RING-type zinc-finger BDV_P24 PF06595.6 CEP19544.1 - 0.0059 16.4 0.8 0.013 15.2 0.3 1.8 1 1 0 1 1 1 1 Borna disease virus P24 protein Nitrate_red_del PF02613.10 CEP19544.1 - 0.014 15.2 2.7 0.96 9.2 0.4 3.1 3 0 0 3 3 3 0 Nitrate reductase delta subunit UCH_1 PF13423.1 CEP19544.1 - 0.03 13.7 4.3 0.042 13.2 3.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ATP-synt_B PF00430.13 CEP19544.1 - 0.23 11.2 5.6 0.097 12.4 1.9 1.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) FliD_C PF07195.7 CEP19544.1 - 0.23 10.7 9.0 1.1 8.4 3.9 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus GLTSCR1 PF15249.1 CEP19544.1 - 0.26 11.4 3.0 0.28 11.3 0.2 2.2 1 1 1 2 2 2 0 Glioma tumor suppressor candidate region Poxvirus_B22R_N PF13169.1 CEP19544.1 - 0.69 10.1 0.0 0.69 10.1 0.0 2.8 3 0 0 3 3 3 0 Poxvirus B22R protein N-terminal MitMem_reg PF13012.1 CEP19544.1 - 0.78 9.8 6.4 0.69 10.0 2.6 2.3 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function OmpH PF03938.9 CEP19544.1 - 3.3 7.6 12.2 1.9 8.4 5.8 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.6 CEP19544.1 - 3.3 8.1 7.6 6.7 7.1 2.4 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal UPF0449 PF15136.1 CEP19544.1 - 7.8 6.7 8.4 3.4 7.9 1.0 2.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 UCH PF00443.24 CEP19545.1 - 2.9e-51 174.1 0.0 3.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEP19545.1 - 1.2e-21 77.4 0.4 3.8e-21 75.8 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CEP19545.1 - 3.3e-10 39.2 0.6 1.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 CEP19545.1 - 0.062 13.5 0.0 0.22 11.8 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain HtrL_YibB PF09612.5 CEP19545.1 - 0.13 11.5 1.8 0.24 10.5 1.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Nop PF01798.13 CEP19546.1 - 1.5e-39 134.6 1.9 2.3e-39 134.0 0.1 2.1 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 CEP19546.1 - 3.3e-36 124.4 1.0 3.3e-36 124.4 0.7 2.3 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 CEP19546.1 - 2.7e-22 78.3 0.1 5.6e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain Glycos_transf_N PF04413.11 CEP19546.1 - 0.011 14.9 0.7 3.2 6.8 0.1 2.3 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Peptidase_M2 PF01401.13 CEP19546.1 - 0.35 8.9 2.3 0.43 8.7 1.6 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme Pyr_redox PF00070.22 CEP19547.1 - 1.6e-16 60.4 0.0 5.2e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEP19547.1 - 2.4e-15 56.9 1.0 3.7e-07 30.2 0.0 4.1 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.14 CEP19547.1 - 4.1e-10 39.7 1.3 8e-10 38.8 0.9 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.19 CEP19547.1 - 4.5e-08 32.3 0.0 0.22 10.3 0.0 3.6 2 2 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CEP19547.1 - 3e-05 23.8 0.4 4.3 7.0 0.0 4.3 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CEP19547.1 - 5.6e-05 23.3 0.0 0.44 10.5 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEP19547.1 - 6.3e-05 22.0 0.0 0.034 13.0 0.0 2.6 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEP19547.1 - 0.0011 18.8 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CEP19547.1 - 0.012 14.5 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 CEP19547.1 - 0.013 14.1 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase RGS-like PF09128.6 CEP19547.1 - 0.04 13.4 0.4 0.093 12.2 0.1 1.7 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain DUF1188 PF06690.6 CEP19547.1 - 0.092 11.8 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) RhoGEF PF00621.15 CEP19548.1 - 1.7e-29 103.0 3.2 1.7e-29 103.0 2.2 2.1 2 0 0 2 2 2 1 RhoGEF domain HEAT PF02985.17 CEP19550.1 - 1.5e-43 142.9 24.4 0.00017 21.3 0.0 22.2 24 0 0 24 24 23 7 HEAT repeat DUF3554 PF12074.3 CEP19550.1 - 8.5e-42 143.7 0.5 8.5e-42 143.7 0.3 3.9 4 1 1 5 5 5 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 CEP19550.1 - 1.9e-32 111.3 48.6 1.2e-05 25.4 0.2 17.2 7 4 10 17 17 17 12 HEAT repeats HEAT_EZ PF13513.1 CEP19550.1 - 1.1e-28 98.9 51.9 0.0067 16.8 0.0 21.3 15 4 9 24 24 24 8 HEAT-like repeat CLASP_N PF12348.3 CEP19550.1 - 4.4e-11 42.5 0.0 0.013 14.9 0.0 6.8 5 2 0 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 CEP19550.1 - 3.3e-10 40.2 0.2 1.8 8.9 0.0 7.7 7 1 1 8 8 8 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 CEP19550.1 - 1.5e-08 33.4 17.9 0.025 12.8 0.1 8.4 6 2 2 8 8 8 5 Adaptin N terminal region Cnd1 PF12717.2 CEP19550.1 - 2.8e-08 33.8 0.1 0.0014 18.5 0.0 5.7 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 CEP19550.1 - 2.6e-07 30.7 3.7 0.21 11.4 0.0 5.9 4 2 1 6 6 6 2 Parkin co-regulated protein Arm PF00514.18 CEP19550.1 - 0.00027 20.6 4.6 49 3.9 0.0 8.7 8 1 1 9 9 9 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 CEP19550.1 - 0.031 14.2 0.1 4.9 7.1 0.0 4.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MIT PF04212.13 CEP19551.1 - 0.00024 20.9 0.1 0.0015 18.4 0.1 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Mob1_phocein PF03637.12 CEP19552.1 - 1.5e-59 200.5 2.2 3.1e-53 180.0 0.5 2.1 1 1 1 2 2 2 2 Mob1/phocein family DUF1075 PF06388.6 CEP19552.1 - 0.092 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) DPBB_1 PF03330.13 CEP19553.1 - 2e-15 56.5 0.1 2.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP19553.1 - 0.0016 18.1 1.0 0.0048 16.5 0.1 1.9 1 1 1 2 2 2 1 Barwin family Tubulin_3 PF14881.1 CEP19554.1 - 0.15 11.5 1.1 16 4.8 0.0 2.9 3 0 0 3 3 3 0 Tubulin domain MHYT PF03707.11 CEP19555.1 - 2.2e-14 53.3 8.6 8.5e-07 28.9 0.0 4.2 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat Ldr_toxin PF13940.1 CEP19555.1 - 2.4 7.9 4.5 6.3 6.6 3.1 1.7 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system p450 PF00067.17 CEP19556.1 - 4.4e-77 259.5 0.0 5.9e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Alg6_Alg8 PF03155.10 CEP19557.1 - 5.2e-135 450.9 27.0 6.4e-135 450.6 18.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family FAD_binding_1 PF00667.15 CEP19558.1 - 1.1e-44 152.5 0.0 1.8e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CEP19558.1 - 3.6e-27 95.1 0.3 1e-26 93.6 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 CEP19558.1 - 2.8e-17 63.2 0.0 1.1e-16 61.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 CEP19558.1 - 0.026 13.9 0.0 0.066 12.6 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain EamA PF00892.15 CEP19559.1 - 3.9e-10 39.8 32.8 5.3e-06 26.4 4.5 3.2 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 CEP19559.1 - 4.2e-06 25.8 9.1 6.5e-06 25.2 6.3 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 CEP19559.1 - 9.1e-06 25.8 25.6 0.0003 20.9 2.2 2.6 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 CEP19559.1 - 0.0077 15.8 7.0 0.0077 15.8 4.8 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CEP19559.1 - 0.042 12.7 15.4 0.14 11.0 10.7 1.8 1 1 0 1 1 1 0 UAA transporter family DUF155 PF02582.9 CEP19560.1 - 6e-15 55.5 0.0 8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UbiA PF01040.13 CEP19561.1 - 5.1e-36 124.2 16.8 6.4e-36 123.8 11.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ricin_B_lectin PF00652.17 CEP19562.1 - 1.9e-12 47.2 0.9 4.4e-12 46.1 0.4 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP19562.1 - 2.3e-08 34.3 0.6 8.8e-06 26.0 0.1 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like NCU-G1 PF15065.1 CEP19564.1 - 1.2e-05 24.2 0.8 2.1e-05 23.4 0.5 1.3 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 DUF1073 PF06381.6 CEP19565.1 - 0.024 13.0 1.8 0.044 12.2 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) LRR_4 PF12799.2 CEP19566.1 - 3e-26 90.5 47.9 2.9e-05 23.5 0.1 7.5 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP19566.1 - 3.7e-25 87.4 35.5 1.1e-08 34.6 1.9 5.0 2 2 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 CEP19566.1 - 4e-19 65.6 36.7 0.06 13.3 0.2 11.7 11 0 0 11 11 11 8 Leucine Rich Repeat LRR_6 PF13516.1 CEP19566.1 - 2.8e-07 29.9 42.2 0.27 11.4 0.4 10.3 12 0 0 12 12 12 5 Leucine Rich repeat LRR_7 PF13504.1 CEP19566.1 - 2.1e-05 23.9 35.7 0.58 10.5 0.1 11.0 13 0 0 13 13 13 3 Leucine rich repeat Mucin PF01456.12 CEP19566.1 - 0.014 15.1 13.5 0.024 14.3 9.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein LRRNT_2 PF08263.7 CEP19566.1 - 0.068 13.1 2.4 0.18 11.7 1.7 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain C2 PF00168.25 CEP19567.1 - 5.1e-22 77.5 0.1 7.5e-22 76.9 0.1 1.3 1 0 0 1 1 1 1 C2 domain Aminotran_1_2 PF00155.16 CEP19568.1 - 6.2e-60 203.0 0.0 7.1e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEP19568.1 - 1.5e-06 27.5 0.0 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CEP19568.1 - 0.00043 18.6 0.0 0.00066 18.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CEP19568.1 - 0.00086 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CEP19568.1 - 0.018 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Polysacc_deac_1 PF01522.16 CEP19569.1 - 4.2e-09 36.0 0.0 8.8e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Gcd10p PF04189.8 CEP19570.1 - 1.6e-76 257.2 0.6 2.4e-76 256.7 0.4 1.2 1 0 0 1 1 1 1 Gcd10p family Cpn60_TCP1 PF00118.19 CEP19571.1 - 3.1e-149 497.7 3.4 3.6e-149 497.4 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RhoGAP PF00620.22 CEP19572.1 - 2.2e-36 124.7 0.0 5.9e-36 123.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CEP19572.1 - 2.4e-31 107.5 45.7 1e-12 47.8 5.1 5.1 5 0 0 5 5 5 4 LIM domain YebO PF13974.1 CEP19573.1 - 0.15 11.8 0.4 0.32 10.8 0.3 1.5 1 0 0 1 1 1 0 YebO-like protein Amidohydro_1 PF01979.15 CEP19575.1 - 3.9e-12 46.4 0.0 8.5e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CEP19575.1 - 8e-09 35.9 0.0 0.0035 17.4 0.0 3.1 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_3 PF07969.6 CEP19575.1 - 6.6e-06 25.5 0.0 3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 CEP19575.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase Peptidase_S26 PF10502.4 CEP19576.1 - 1.7e-07 30.8 0.0 0.00032 20.2 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 CEP19576.1 - 1.5e-06 27.7 0.1 2.5e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like GST_N_3 PF13417.1 CEP19577.1 - 1.1e-15 57.6 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP19577.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP19577.1 - 0.081 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Aldolase_II PF00596.16 CEP19577.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain GST_C_2 PF13410.1 CEP19577.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAR1 PF03101.10 CEP19578.1 - 0.0078 16.7 0.1 0.013 16.0 0.1 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AAA PF00004.24 CEP19579.1 - 3.3e-20 72.6 0.0 5.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 CEP19579.1 - 3.6e-09 36.4 0.0 1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.1 CEP19579.1 - 4.8e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.9 CEP19579.1 - 6e-06 26.0 0.0 2.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEP19579.1 - 0.00013 21.0 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CEP19579.1 - 0.00035 21.3 0.0 0.0017 19.1 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CEP19579.1 - 0.0014 18.2 0.2 0.0091 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEP19579.1 - 0.0014 18.7 0.0 0.021 15.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 CEP19579.1 - 0.0016 18.5 0.0 0.0042 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CEP19579.1 - 0.005 16.5 0.0 0.18 11.4 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_25 PF13481.1 CEP19579.1 - 0.0083 15.5 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CEP19579.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 CEP19579.1 - 0.011 16.0 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CEP19579.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEP19579.1 - 0.011 15.5 0.0 0.04 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CEP19579.1 - 0.012 16.0 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein DUF815 PF05673.8 CEP19579.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 CEP19579.1 - 0.023 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_ab PF00006.20 CEP19579.1 - 0.027 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 CEP19579.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEP19579.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CEP19579.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Thioredoxin PF00085.15 CEP19580.1 - 1.1e-06 28.2 0.1 2.4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin SAPS PF04499.10 CEP19580.1 - 0.04 12.5 0.9 0.062 11.9 0.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MFS_1 PF07690.11 CEP19581.1 - 2e-17 62.9 37.5 2e-17 62.9 26.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CEP19581.1 - 1.4 7.1 30.2 0.41 8.9 8.3 3.0 2 1 2 4 4 4 0 MFS/sugar transport protein DDOST_48kD PF03345.9 CEP19582.1 - 1.1e-122 409.6 2.7 1.4e-122 409.3 1.9 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Helitron_like_N PF14214.1 CEP19589.1 - 6.3e-21 74.9 0.0 1.1e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Flu_NS2 PF00601.14 CEP19590.1 - 0.11 12.6 0.3 0.24 11.6 0.1 1.6 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) DDE_3 PF13358.1 CEP19591.1 - 5.9e-08 32.5 0.0 9.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.8 CEP19591.1 - 0.00019 20.7 0.0 0.00045 19.5 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.1 CEP19591.1 - 0.00036 20.6 0.1 0.00099 19.2 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_psq PF05225.11 CEP19591.1 - 0.00081 18.8 0.0 0.0057 16.1 0.0 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_32 PF13565.1 CEP19591.1 - 0.003 18.3 0.1 0.015 16.0 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP19591.1 - 0.0038 17.2 0.3 0.011 15.7 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP19591.1 - 0.05 13.2 0.2 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain TrmB PF01978.14 CEP19591.1 - 0.15 11.8 0.5 0.56 9.9 0.0 2.3 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Transposase_21 PF02992.9 CEP19592.1 - 1e-08 34.5 0.5 1e-08 34.5 0.3 1.7 1 1 1 2 2 2 1 Transposase family tnp2 DDE_Tnp_1_7 PF13843.1 CEP19593.1 - 0.00064 18.8 0.0 0.00066 18.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 PDH PF02153.12 CEP19597.1 - 1e-14 54.0 0.0 1.4e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 CEP19597.1 - 8.8e-05 22.8 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CEP19597.1 - 0.00073 18.9 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 CEP19597.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 CEP19597.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 CEP19597.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CEP19597.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.7 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3112 PF11309.3 CEP19598.1 - 0.0077 16.0 1.1 0.0077 16.0 0.8 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3112) TB2_DP1_HVA22 PF03134.14 CEP19598.1 - 0.073 12.8 7.0 0.4 10.4 0.2 2.5 2 0 0 2 2 2 0 TB2/DP1, HVA22 family CoA_binding_3 PF13727.1 CEP19598.1 - 3 7.6 8.1 0.1 12.4 0.4 2.0 1 1 1 2 2 2 0 CoA-binding domain Pox_A28 PF04584.9 CEP19598.1 - 4.1 7.2 6.7 4.6 7.1 0.1 2.5 2 1 0 2 2 2 0 Poxvirus A28 family Glycos_transf_1 PF00534.15 CEP19599.1 - 3.4e-30 104.7 0.0 5.2e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CEP19599.1 - 3.3e-15 56.5 0.1 6.3e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CEP19599.1 - 5.8e-14 52.1 0.0 8.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CEP19599.1 - 4.3e-13 49.5 0.0 9.8e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CEP19599.1 - 6.6e-05 23.1 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Rib_hydrolayse PF02267.12 CEP19599.1 - 0.071 12.4 0.4 0.12 11.6 0.3 1.3 1 0 0 1 1 1 0 ADP-ribosyl cyclase Reprolysin_5 PF13688.1 CEP19600.1 - 2.9e-43 148.1 9.0 2.9e-43 148.1 6.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 CEP19600.1 - 4.9e-42 143.7 4.0 9.4e-42 142.8 2.8 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CEP19600.1 - 5.9e-38 130.6 5.3 1.3e-37 129.5 3.7 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CEP19600.1 - 1.1e-19 71.2 0.2 1.1e-19 71.2 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CEP19600.1 - 3.1e-17 62.5 23.4 3.1e-17 62.5 16.2 4.1 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 CEP19600.1 - 0.00093 18.9 0.1 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.14 CEP19600.1 - 0.0017 18.0 13.4 0.042 13.4 9.3 2.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease GP41 PF00517.12 CEP19600.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral envelope protein H_PPase PF03030.11 CEP19601.1 - 1.6 6.8 9.0 0.7 8.0 3.9 1.5 1 1 0 1 1 1 0 Inorganic H+ pyrophosphatase MMR_HSR1 PF01926.18 CEP19602.1 - 6.1e-14 51.9 1.0 1.1e-06 28.6 0.0 2.7 1 1 1 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP19602.1 - 2.5e-12 46.6 0.1 9.5e-09 34.9 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain KH_2 PF07650.12 CEP19602.1 - 2.2e-09 36.7 0.5 5.7e-09 35.4 0.4 1.7 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.18 CEP19602.1 - 1.7e-06 27.9 0.5 0.00015 21.6 0.1 2.8 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 CEP19602.1 - 2.2e-05 24.9 0.3 0.00053 20.4 0.2 2.8 1 1 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 CEP19602.1 - 2.6e-05 23.9 0.1 0.00028 20.5 0.1 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 CEP19602.1 - 3e-05 23.3 0.8 0.0041 16.4 0.1 2.5 1 1 1 2 2 2 2 Ferrous iron transport protein B cobW PF02492.14 CEP19602.1 - 0.00038 19.9 0.5 0.02 14.3 0.0 2.5 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CEP19602.1 - 0.00053 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CEP19602.1 - 0.00056 19.4 0.0 0.011 15.2 0.0 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CEP19602.1 - 0.0023 18.2 0.0 0.0062 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 CEP19602.1 - 0.0098 15.3 0.1 0.036 13.5 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain GBP PF02263.14 CEP19602.1 - 0.01 14.8 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain G-alpha PF00503.15 CEP19602.1 - 0.012 14.3 1.9 0.62 8.6 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Arf PF00025.16 CEP19602.1 - 0.014 14.6 0.3 0.37 10.0 0.2 2.3 1 1 0 1 1 1 0 ADP-ribosylation factor family RNA_helicase PF00910.17 CEP19602.1 - 0.014 15.5 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 CEP19602.1 - 0.048 14.4 0.1 0.16 12.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain Flavoprotein PF02441.14 CEP19603.1 - 3.2e-30 104.4 0.2 8.3e-30 103.1 0.1 1.7 1 0 0 1 1 1 1 Flavoprotein SH3_1 PF00018.23 CEP19603.1 - 3.5e-10 39.1 0.1 6.4e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEP19603.1 - 2.4e-09 36.6 0.3 5.7e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CEP19603.1 - 4.7e-07 29.2 0.0 7.9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_4 PF12763.2 CEP19603.1 - 0.00017 21.2 2.2 0.00033 20.3 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CEP19603.1 - 0.065 12.5 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF4218 PF13960.1 CEP19605.1 - 0.00096 18.5 0.5 0.0067 15.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) NIF PF03031.13 CEP19605.1 - 0.054 13.1 0.2 0.13 11.9 0.1 1.7 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase TFIIA PF03153.8 CEP19606.1 - 0.062 13.1 8.3 0.082 12.7 5.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OrfB_Zn_ribbon PF07282.6 CEP19606.1 - 0.094 12.3 7.2 0.1 12.3 2.3 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Retinal PF15449.1 CEP19606.1 - 2.6 5.5 15.2 3.4 5.1 10.5 1.1 1 0 0 1 1 1 0 Retinal protein UvrD_C_2 PF13538.1 CEP19607.1 - 0.00014 21.9 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Lar_restr_allev PF14354.1 CEP19607.1 - 0.0016 18.7 1.0 0.0034 17.6 0.7 1.6 1 1 0 1 1 1 1 Restriction alleviation protein Lar Herpes_Helicase PF02689.9 CEP19607.1 - 0.0032 15.2 0.0 0.0043 14.8 0.0 1.1 1 0 0 1 1 1 1 Helicase GFA PF04828.9 CEP19607.1 - 0.0099 15.7 1.4 0.021 14.7 1.0 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Viral_helicase1 PF01443.13 CEP19607.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase zf-LITAF-like PF10601.4 CEP19607.1 - 0.16 11.8 0.9 8.6 6.3 0.1 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Ogr_Delta PF04606.7 CEP19607.1 - 0.16 11.6 7.5 4.2 7.0 0.2 3.9 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf-Di19 PF05605.7 CEP19607.1 - 0.45 10.6 2.7 8.8 6.5 0.5 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.1 CEP19607.1 - 0.52 9.5 2.5 5.6 6.3 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC PF00098.18 CEP19607.1 - 0.73 9.8 3.3 0.31 11.0 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 CEP19608.1 - 0.00022 21.0 1.7 0.00038 20.2 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEP19608.1 - 0.018 15.0 0.0 0.061 13.3 0.0 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_5 PF14787.1 CEP19608.1 - 0.025 14.0 2.7 0.05 13.0 1.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RPAP1_C PF08620.5 CEP19609.1 - 0.024 14.5 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 RPAP1-like, C-terminal Baculo_PEP_C PF04513.7 CEP19610.1 - 0.012 15.4 0.1 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_T7_Capsid PF05396.6 CEP19610.1 - 0.067 13.3 0.7 0.11 12.6 0.4 1.3 1 1 0 1 1 1 0 Phage T7 capsid assembly protein SpoIIID PF12116.3 CEP19610.1 - 0.068 13.1 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Stage III sporulation protein D EzrA PF06160.7 CEP19610.1 - 0.072 11.2 0.0 0.082 11.0 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4021 PF13213.1 CEP19610.1 - 0.15 11.7 0.2 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4021) Myb_DNA-bind_4 PF13837.1 CEP19611.1 - 0.014 15.4 1.5 0.099 12.7 0.1 2.5 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain DDE_3 PF13358.1 CEP19613.1 - 4.7e-07 29.6 0.0 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP19613.1 - 0.0003 20.9 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP19613.1 - 0.0086 15.7 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP19613.1 - 0.015 15.2 0.7 0.21 11.6 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain LBP_BPI_CETP PF01273.20 CEP19616.1 - 0.12 11.6 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain Helitron_like_N PF14214.1 CEP19617.1 - 2.9e-21 76.0 0.2 2.5e-19 69.7 0.0 3.1 2 1 1 3 3 3 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 CEP19617.1 - 2.7e-15 56.1 0.0 4.2e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 CEP19617.1 - 0.00013 22.0 0.0 0.00072 19.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CEP19617.1 - 0.04 13.6 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CEP19617.1 - 0.053 13.0 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CEP19617.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Gar1 PF04410.9 CEP19617.1 - 0.19 11.1 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region PIF1 PF05970.9 CEP19618.1 - 3.8e-79 266.2 0.0 4.6e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP19618.1 - 1.8e-06 26.0 0.0 6.7e-05 20.8 0.0 2.0 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.1 CEP19618.1 - 0.0032 17.5 0.0 0.006 16.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helitron_like_N PF14214.1 CEP19619.1 - 6e-78 260.7 0.0 2.9e-39 134.7 0.0 2.9 3 0 0 3 3 3 2 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 CEP19619.1 - 2.9e-71 240.3 0.1 9e-71 238.7 0.1 1.7 2 0 0 2 2 2 1 PIF1-like helicase Herpes_Helicase PF02689.9 CEP19619.1 - 1.5e-07 29.6 0.0 2.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 CEP19619.1 - 0.00018 21.5 0.0 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DZR PF12773.2 CEP19619.1 - 1.8 8.4 6.0 1.2 8.9 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_L32e PF01655.13 CEP19620.1 - 0.0085 16.1 0.1 0.0099 15.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 TPD PF14811.1 CEP19620.1 - 0.11 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif DUF1814 PF08843.6 CEP19622.1 - 0.089 12.5 0.1 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF1814) Methyltransf_11 PF08241.7 CEP19624.1 - 1.1e-15 57.8 0.0 2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP19624.1 - 9.7e-11 41.4 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEP19624.1 - 4.7e-06 25.9 0.0 1.3e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CEP19624.1 - 4.8e-06 26.9 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP19624.1 - 6.4e-06 26.7 0.0 1.6e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP19624.1 - 5.9e-05 22.8 0.0 9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP19624.1 - 0.00018 21.8 0.0 0.0004 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CEP19624.1 - 0.046 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.5 CEP19624.1 - 0.099 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Iron_permease PF04120.7 CEP19625.1 - 7.3e-41 138.8 5.6 3.7e-17 62.1 0.1 4.2 3 1 1 4 4 4 4 Low affinity iron permease DUF4319 PF14203.1 CEP19625.1 - 0.11 12.0 0.2 1 8.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) DUF3661 PF12400.3 CEP19626.1 - 7.8e-34 116.5 6.4 1.7e-33 115.4 4.4 1.6 1 0 0 1 1 1 1 Vaculolar membrane protein Abhydrolase_3 PF07859.8 CEP19627.1 - 1.2e-31 109.9 0.0 3.7e-31 108.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEP19627.1 - 4.7e-16 58.3 0.8 1e-10 40.8 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 CEP19627.1 - 4.3e-05 23.4 0.0 7.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEP19627.1 - 0.00026 20.7 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP19627.1 - 0.004 16.7 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEP19627.1 - 0.0054 15.9 0.1 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 CEP19627.1 - 0.027 13.1 1.0 4.3 5.9 0.0 2.6 3 0 0 3 3 3 0 Carboxylesterase family DUF837 PF05769.6 CEP19628.1 - 3.1e-05 23.6 16.8 0.00021 20.8 11.7 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF837) CCDC-167 PF15188.1 CEP19628.1 - 0.0023 17.8 2.1 0.0023 17.8 1.5 3.3 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 167 FliT PF05400.8 CEP19628.1 - 0.007 16.7 1.3 0.007 16.7 0.9 3.7 3 1 1 4 4 4 1 Flagellar protein FliT IL4 PF00727.13 CEP19628.1 - 0.49 10.2 3.2 0.56 10.0 0.5 2.1 2 1 0 2 2 2 0 Interleukin 4 DUF745 PF05335.8 CEP19628.1 - 0.93 8.9 11.8 0.22 11.0 3.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF745) EHN PF06441.7 CEP19628.1 - 1.1 9.2 4.0 3.5 7.5 0.9 2.6 2 1 0 2 2 2 0 Epoxide hydrolase N terminus V_ATPase_I PF01496.14 CEP19628.1 - 1.4 6.6 10.1 1.9 6.2 7.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Microtub_assoc PF07989.6 CEP19628.1 - 3 7.7 15.0 2 8.2 0.1 4.0 4 0 0 4 4 4 0 Microtubule associated DUF972 PF06156.8 CEP19628.1 - 3.2 8.1 21.8 0.66 10.3 2.8 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 CEP19628.1 - 3.4 7.2 20.1 2.6 7.5 1.5 3.9 2 1 2 4 4 4 0 Septum formation initiator DUF4164 PF13747.1 CEP19628.1 - 3.6 7.8 8.7 0.62 10.2 2.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF724 PF05266.9 CEP19628.1 - 4.3 6.9 11.7 1.3 8.6 4.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GnsAB PF08178.6 CEP19628.1 - 5.7 6.6 6.2 0.87 9.2 0.8 2.1 2 0 0 2 2 2 0 GnsA/GnsB family Caleosin PF05042.8 CEP19630.1 - 0.024 14.2 0.1 0.076 12.5 0.0 1.8 2 0 0 2 2 2 0 Caleosin related protein Sugar_tr PF00083.19 CEP19631.1 - 2.9e-103 345.8 31.4 1.2e-52 179.0 11.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP19631.1 - 2.9e-29 101.8 28.9 1.1e-28 100.0 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEP19631.1 - 0.0042 15.5 40.8 0.0051 15.2 8.9 4.1 2 2 2 4 4 4 3 MFS/sugar transport protein DUF4341 PF14241.1 CEP19631.1 - 0.03 14.0 9.9 0.02 14.5 4.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) DnaJ PF00226.26 CEP19632.1 - 6.1e-24 83.5 3.5 1e-23 82.7 2.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CEP19632.1 - 4.2e-18 65.0 0.0 2.2e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CEP19632.1 - 0.00032 20.6 10.1 0.00065 19.6 7.0 1.5 1 1 0 1 1 1 1 DnaJ central domain zf-C2H2_2 PF12756.2 CEP19633.1 - 0.00018 21.5 0.8 0.00049 20.1 0.3 1.8 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CEP19633.1 - 0.00045 20.3 5.8 0.064 13.6 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEP19633.1 - 0.0011 19.2 8.0 0.0015 18.7 0.1 3.1 2 1 0 2 2 2 1 Zinc finger, C2H2 type RNA_POL_M_15KD PF02150.11 CEP19633.1 - 0.0071 16.0 1.8 0.092 12.4 0.1 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-met PF12874.2 CEP19633.1 - 0.014 15.6 0.0 0.041 14.0 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CEP19633.1 - 0.022 14.6 0.0 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 CEP19633.1 - 0.026 14.6 2.3 6.2 7.0 0.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.1 CEP19633.1 - 0.033 13.7 1.4 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CEP19633.1 - 0.041 13.5 1.5 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Gp_dh_C PF02800.15 CEP19634.1 - 6.9e-74 246.5 0.1 1.1e-73 245.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CEP19634.1 - 3.1e-60 202.5 0.5 6e-60 201.5 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CEP19634.1 - 0.0025 17.6 0.2 0.0091 15.9 0.1 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 CEP19634.1 - 0.072 12.6 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Uteroglobin PF01099.12 CEP19635.1 - 0.0082 15.9 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 Uteroglobin family RSS_P20 PF11757.3 CEP19635.1 - 0.021 14.9 0.5 0.045 13.8 0.4 1.5 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like MOZ_SAS PF01853.13 CEP19635.1 - 0.021 14.0 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 MOZ/SAS family CagY_I PF14585.1 CEP19635.1 - 0.28 11.1 5.1 0.15 11.9 1.8 1.8 2 0 0 2 2 2 0 CagY type 1 repeat SWIB PF02201.13 CEP19636.1 - 5.4e-13 48.4 0.1 2.2e-11 43.2 0.0 3.1 2 1 1 3 3 3 1 SWIB/MDM2 domain Yip1 PF04893.12 CEP19636.1 - 5.9e-11 42.1 7.9 9.6e-11 41.4 5.4 1.2 1 0 0 1 1 1 1 Yip1 domain DUF2374 PF09574.5 CEP19636.1 - 0.057 13.0 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) DUF2955 PF11168.3 CEP19636.1 - 0.3 10.7 6.5 0.19 11.4 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2955) AAA_2 PF07724.9 CEP19637.1 - 5.1e-45 153.4 0.3 4e-44 150.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CEP19637.1 - 2.3e-16 60.1 0.1 4.1e-15 56.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CEP19637.1 - 1.3e-12 47.3 0.1 1.3e-12 47.3 0.1 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CEP19637.1 - 6.6e-07 29.1 0.0 2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.10 CEP19637.1 - 2.3e-06 27.5 1.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 CEP19637.1 - 4.1e-06 26.0 0.3 0.0012 18.0 0.0 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CEP19637.1 - 1.9e-05 24.2 0.0 0.0085 15.5 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 CEP19637.1 - 2.5e-05 24.3 3.8 0.004 17.2 0.1 3.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CEP19637.1 - 5.4e-05 22.6 0.2 0.00075 18.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CEP19637.1 - 0.00026 21.7 0.0 0.001 19.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 CEP19637.1 - 0.00031 20.8 0.8 0.0011 19.0 0.0 2.3 3 0 0 3 3 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 CEP19637.1 - 0.00046 19.3 0.5 0.007 15.4 0.1 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CEP19637.1 - 0.00062 19.6 0.2 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CEP19637.1 - 0.0012 18.7 1.6 0.0057 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEP19637.1 - 0.0013 18.7 0.3 0.0013 18.7 0.2 2.2 2 1 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.22 CEP19637.1 - 0.0024 18.1 0.3 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 CEP19637.1 - 0.0026 17.4 0.6 0.046 13.3 0.0 2.6 3 0 0 3 3 2 1 NACHT domain T2SE PF00437.15 CEP19637.1 - 0.003 16.5 0.0 0.003 16.5 0.0 1.6 2 0 0 2 2 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 CEP19637.1 - 0.0042 16.5 0.0 0.0092 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CEP19637.1 - 0.0095 16.2 1.2 0.06 13.6 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.1 CEP19637.1 - 0.013 15.8 6.8 0.096 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CEP19637.1 - 0.014 15.0 1.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CEP19637.1 - 0.017 14.3 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 CEP19637.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 CEP19637.1 - 0.023 14.1 0.0 0.65 9.3 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain MCM PF00493.18 CEP19637.1 - 0.024 13.4 0.6 0.15 10.7 0.1 2.3 2 1 0 2 2 2 0 MCM2/3/5 family UPF0079 PF02367.12 CEP19637.1 - 0.037 13.6 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 CEP19637.1 - 0.042 13.7 1.3 0.59 9.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase TIP49 PF06068.8 CEP19637.1 - 0.06 12.0 0.2 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_28 PF13521.1 CEP19637.1 - 0.06 13.3 1.8 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 CEP19637.1 - 0.11 12.1 0.6 0.18 11.3 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CEP19637.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CEP19637.1 - 0.12 12.5 0.0 0.42 10.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.24 CEP19637.1 - 0.15 11.5 0.0 0.15 11.5 0.0 2.4 2 1 0 3 3 3 0 DEAD/DEAH box helicase G-alpha PF00503.15 CEP19637.1 - 1.7 7.2 6.3 3.6 6.1 4.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit Gar1 PF04410.9 CEP19639.1 - 2.3e-37 127.8 1.9 2.3e-37 127.8 1.3 2.8 1 1 2 3 3 3 2 Gar1/Naf1 RNA binding region DUF3546 PF12066.3 CEP19640.1 - 2.7e-17 62.7 7.3 2.7e-17 62.7 5.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 CEP19640.1 - 9.6e-17 61.8 0.1 9.6e-17 61.8 0.1 1.8 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 CEP19640.1 - 3.2e-13 49.0 2.2 8.3e-13 47.7 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.17 CEP19640.1 - 0.00025 20.6 0.0 0.00054 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.1 CEP19640.1 - 0.0059 16.8 2.3 0.35 11.2 0.1 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger Polysacc_deac_1 PF01522.16 CEP19641.1 - 3e-26 91.4 0.0 5.9e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEP19641.1 - 0.005 15.7 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Stc1 PF12898.2 CEP19643.1 - 3.3e-17 62.3 6.8 4.5e-17 61.8 4.7 1.2 1 0 0 1 1 1 1 Stc1 domain zf-CHY PF05495.7 CEP19643.1 - 1.5 9.0 8.9 15 5.8 6.2 2.1 1 1 0 1 1 1 0 CHY zinc finger zf-RING_5 PF14634.1 CEP19643.1 - 1.6 8.4 8.3 5 6.9 3.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-CXXC PF02008.15 CEP19643.1 - 4.4 7.1 8.9 12 5.7 6.2 1.7 1 1 0 1 1 1 0 CXXC zinc finger domain Pyr_redox_2 PF07992.9 CEP19644.1 - 1.2e-23 84.0 0.0 2e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEP19644.1 - 4.8e-15 55.7 0.0 3.5e-11 43.3 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 CEP19644.1 - 1.6e-11 44.1 0.6 8.8e-05 22.5 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CEP19644.1 - 7.7e-11 40.4 2.5 0.00022 20.2 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CEP19644.1 - 2.8e-09 36.0 1.5 0.00022 20.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CEP19644.1 - 4.7e-07 28.8 0.9 0.034 13.4 0.0 2.5 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.1 CEP19644.1 - 2.2e-06 27.9 0.0 0.39 10.7 0.0 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 CEP19644.1 - 0.0016 18.0 2.3 0.49 10.0 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CEP19644.1 - 0.022 14.8 2.6 0.96 9.5 0.0 3.0 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Bunya_G1 PF03557.10 CEP19644.1 - 0.097 10.4 0.0 0.14 9.9 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 DUF4598 PF15370.1 CEP19646.1 - 1.7e-20 73.3 3.0 2.9e-20 72.6 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) DPBB_1 PF03330.13 CEP19647.1 - 1e-06 28.6 1.6 2.7e-06 27.2 0.6 2.1 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEP19647.1 - 0.0006 19.4 0.9 0.00083 19.0 0.7 1.2 1 0 0 1 1 1 1 Barwin family Sar8_2 PF03058.9 CEP19647.1 - 5.6 7.3 8.4 1.3e+02 2.9 5.8 2.3 1 1 0 1 1 1 0 Sar8.2 family Med15_fungi PF05397.7 CEP19648.1 - 1.4e-22 79.8 0.2 1.4e-22 79.8 0.1 10.4 7 4 4 11 11 11 1 Mediator complex subunit 15 Asparaginase PF00710.15 CEP19649.1 - 3.6e-118 393.9 0.0 4.8e-118 393.5 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 CEP19649.1 - 4.5e-23 81.3 0.1 9.8e-17 61.0 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEP19649.1 - 8.6e-17 60.7 1.2 4.2e-10 39.5 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP19649.1 - 1.2e-14 54.3 0.7 8.6e-07 29.3 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CEP19649.1 - 2.9e-14 52.0 3.1 4.5e-08 32.5 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 CEP19649.1 - 9.9e-12 43.9 1.9 0.00016 21.5 0.1 5.5 6 0 0 6 6 6 2 Ankyrin repeat zf-DNL PF05180.7 CEP19649.1 - 0.15 11.8 0.1 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 DNL zinc finger PhosphMutase PF10143.4 CEP19651.1 - 1e-50 171.7 0.0 1.7e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Pkinase PF00069.20 CEP19651.1 - 2e-48 164.7 2.7 3.3e-46 157.5 1.9 2.2 1 1 0 1 1 1 1 Protein kinase domain Metalloenzyme PF01676.13 CEP19651.1 - 1.9e-36 125.7 0.0 3.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Pkinase_Tyr PF07714.12 CEP19651.1 - 2.4e-13 49.7 0.6 5.9e-10 38.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CEP19651.1 - 6.2e-05 22.8 0.1 0.00025 20.8 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Phosphodiest PF01663.17 CEP19651.1 - 9.5e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Choline_kinase PF01633.15 CEP19651.1 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase ATP-synt_S1 PF05827.7 CEP19651.1 - 0.095 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Kdo PF06293.9 CEP19651.1 - 0.12 11.3 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane PF00664.18 CEP19653.1 - 8e-28 97.6 10.2 1.2e-27 97.0 7.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CEP19653.1 - 1e-16 61.4 0.0 1.8e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF1469 PF07332.6 CEP19653.1 - 0.048 13.3 0.3 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) YqzM PF14141.1 CEP19653.1 - 1.1 9.0 4.8 6.5 6.6 3.4 2.2 1 1 0 1 1 1 0 YqzM-like protein ABC_membrane PF00664.18 CEP19654.1 - 6.9e-17 61.7 9.2 1.4e-12 47.6 0.2 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEP19654.1 - 1.1e-07 32.2 0.0 3.6e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 CEP19654.1 - 0.00035 20.0 0.0 0.0014 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 CEP19654.1 - 0.022 14.3 0.0 0.081 12.5 0.0 1.8 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_23 PF13476.1 CEP19654.1 - 0.037 14.3 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NESP55 PF06390.7 CEP19654.1 - 0.04 13.2 2.2 0.073 12.4 1.6 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) AAA_29 PF13555.1 CEP19654.1 - 0.043 13.3 0.1 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Nop14 PF04147.7 CEP19654.1 - 0.16 9.8 3.8 0.26 9.1 2.7 1.2 1 0 0 1 1 1 0 Nop14-like family Arch_ATPase PF01637.13 CEP19654.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Sigma70_ner PF04546.8 CEP19654.1 - 0.28 10.7 4.9 0.56 9.7 3.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 CEP19654.1 - 2.9 8.2 5.9 8 6.8 4.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GPI-anchored PF10342.4 CEP19655.1 - 0.022 15.2 0.1 0.23 11.9 0.1 2.2 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Clathrin_lg_ch PF01086.12 CEP19656.1 - 9.1e-45 153.3 10.8 1.2e-44 152.9 7.5 1.2 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 CEP19656.1 - 0.094 12.2 0.3 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Integrase core domain DUF4047 PF13256.1 CEP19656.1 - 0.42 10.5 10.5 0.89 9.5 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DUF4407 PF14362.1 CEP19656.1 - 0.99 8.2 4.9 1.3 7.8 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PBP_sp32 PF07222.7 CEP19656.1 - 2.7 7.1 7.5 4 6.5 5.2 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RNase_PH PF01138.16 CEP19657.1 - 1.8e-20 73.6 0.0 2.8e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CEP19657.1 - 1.4e-12 47.3 0.0 2.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Enolase_C PF00113.17 CEP19658.1 - 1.2e-157 523.4 0.2 1.6e-157 523.0 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CEP19658.1 - 7.4e-57 190.9 0.1 1.3e-56 190.1 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 CEP19658.1 - 0.0024 16.8 0.3 0.014 14.3 0.1 2.1 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 CEP19658.1 - 0.0065 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like DNA_ligase_aden PF01653.13 CEP19658.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Aldo_ket_red PF00248.16 CEP19659.1 - 4.2e-25 88.1 0.1 2.7e-23 82.1 0.0 2.4 1 1 0 1 1 1 1 Aldo/keto reductase family Rer1 PF03248.8 CEP19660.1 - 4.9e-59 198.8 1.8 6.4e-59 198.4 1.3 1.1 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 CEP19660.1 - 0.0011 18.3 0.1 0.0014 18.1 0.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2208 PF09973.4 CEP19660.1 - 0.024 13.8 1.1 0.039 13.1 0.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF4131 PF13567.1 CEP19660.1 - 1.5 8.1 5.5 5.6 6.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Frataxin_Cyay PF01491.11 CEP19661.1 - 7.9e-38 128.5 0.1 9.9e-38 128.2 0.1 1.1 1 0 0 1 1 1 1 Frataxin-like domain NUDIX PF00293.23 CEP19662.1 - 4.1e-10 39.4 0.1 6.7e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain PAP2 PF01569.16 CEP19663.1 - 3.4e-12 46.1 3.0 3.4e-12 46.1 2.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CEP19663.1 - 2e-05 24.2 5.4 4.2e-05 23.1 3.7 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAD_M PF08527.5 CEP19664.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain AAA_5 PF07728.9 CEP19665.1 - 0.02 14.6 0.2 0.075 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Lipocalin PF00061.18 CEP19665.1 - 0.042 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PAXNEB PF05625.6 CEP19666.1 - 1.5e-74 251.0 0.0 3.4e-50 170.9 0.0 2.0 1 1 1 2 2 2 2 PAXNEB protein KaiC PF06745.8 CEP19666.1 - 6.6e-05 22.1 0.1 0.00014 21.0 0.0 1.6 2 0 0 2 2 2 1 KaiC MSA-2c PF12238.3 CEP19666.1 - 0.17 11.4 1.1 0.28 10.8 0.2 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c RabGAP-TBC PF00566.13 CEP19667.1 - 4.8e-35 120.9 2.8 6e-35 120.6 2.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Synaptobrevin PF00957.16 CEP19668.1 - 1.3e-33 114.4 0.8 1.7e-33 114.0 0.5 1.1 1 0 0 1 1 1 1 Synaptobrevin ETRAMP PF09716.5 CEP19668.1 - 0.0082 16.0 0.2 0.011 15.6 0.2 1.5 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF3357 PF11837.3 CEP19668.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TauE PF01925.14 CEP19668.1 - 0.074 12.4 0.1 0.094 12.1 0.1 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF1705 PF08019.7 CEP19668.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) TMEM117 PF15113.1 CEP19668.1 - 0.11 11.0 0.2 0.13 10.7 0.2 1.0 1 0 0 1 1 1 0 TMEM117 protein family DUF2077 PF09850.4 CEP19668.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) ATP-synt_8 PF00895.15 CEP19668.1 - 0.27 11.4 2.9 0.42 10.8 2.0 1.3 1 0 0 1 1 1 0 ATP synthase protein 8 4HB_MCP_1 PF12729.2 CEP19668.1 - 0.5 9.6 3.9 0.5 9.6 0.9 1.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Fzo_mitofusin PF04799.8 CEP19668.1 - 3.9 6.8 6.6 1.5 8.2 0.1 2.1 1 1 1 2 2 2 0 fzo-like conserved region GP41 PF00517.12 CEP19668.1 - 5.3 6.5 6.8 24 4.4 4.7 1.8 1 1 0 1 1 1 0 Retroviral envelope protein F-box-like PF12937.2 CEP19669.1 - 2.6e-06 27.0 0.5 8.8e-06 25.3 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP19669.1 - 0.00014 21.4 0.3 0.00053 19.5 0.2 2.0 1 0 0 1 1 1 1 F-box domain CW_binding_1 PF01473.15 CEP19669.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.5 3 0 0 3 3 3 0 Putative cell wall binding repeat F-box-like PF12937.2 CEP19670.1 - 0.016 14.9 0.2 0.057 13.1 0.1 2.0 1 0 0 1 1 1 0 F-box-like Acetyltransf_1 PF00583.19 CEP19671.1 - 2.7e-14 52.9 0.0 3.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEP19671.1 - 3.1e-10 40.0 0.1 4.5e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEP19671.1 - 5.8e-06 26.3 0.3 7.5e-06 25.9 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEP19671.1 - 7.2e-06 25.6 0.0 9.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CEP19671.1 - 0.00017 21.4 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEP19671.1 - 0.00099 19.2 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEP19671.1 - 0.0027 17.8 0.0 0.0048 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEP19671.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Hyd_WA PF06462.7 CEP19671.1 - 0.094 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Propeller GCR1_C PF12550.3 CEP19672.1 - 3.3e-08 33.2 0.0 8e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Baculo_PEP_C PF04513.7 CEP19672.1 - 0.033 14.0 0.7 0.06 13.1 0.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus WASH-7_C PF14746.1 CEP19672.1 - 0.39 10.3 2.9 26 4.3 2.0 2.4 1 1 0 1 1 1 0 WASH complex subunit 7, C-terminal RasGAP PF00616.14 CEP19674.1 - 2.4e-29 102.4 0.1 1.1e-28 100.3 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 CEP19674.1 - 5.8e-16 58.7 0.4 2.6e-15 56.6 0.3 2.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CEP19674.1 - 0.00014 21.3 0.2 0.00038 19.9 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain TMEM61 PF15105.1 CEP19675.1 - 0.0004 19.9 0.2 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 TMEM61 protein family GoLoco PF02188.12 CEP19675.1 - 0.14 11.5 6.3 0.26 10.6 0.3 4.0 4 0 0 4 4 4 0 GoLoco motif Baculo_PEP_C PF04513.7 CEP19676.1 - 0.023 14.5 10.4 0.029 14.1 3.8 2.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YusW PF14039.1 CEP19676.1 - 0.069 13.4 1.7 2 8.7 0.1 2.6 2 0 0 2 2 2 0 YusW-like protein MCPVI PF02993.9 CEP19676.1 - 0.4 10.7 2.8 0.63 10.1 1.9 1.3 1 0 0 1 1 1 0 Minor capsid protein VI KxDL PF10241.4 CEP19676.1 - 0.72 9.7 11.2 0.059 13.2 0.6 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein End3 PF12761.2 CEP19676.1 - 1 8.9 15.5 1.7 8.2 2.3 2.7 1 1 2 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Laminin_II PF06009.7 CEP19676.1 - 1.5 8.6 9.7 0.2 11.4 2.3 2.3 1 1 1 2 2 2 0 Laminin Domain II Smg4_UPF3 PF03467.10 CEP19677.1 - 3.9e-37 127.9 1.0 3.9e-37 127.9 0.7 2.5 2 1 1 3 3 3 1 Smg-4/UPF3 family SR-25 PF10500.4 CEP19677.1 - 0.0066 15.9 9.4 0.0066 15.9 6.5 4.0 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DASH_Dam1 PF08653.5 CEP19678.1 - 1.1e-09 37.9 0.1 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ins_allergen_rp PF06757.8 CEP19678.1 - 0.01 15.2 0.1 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Mito_carr PF00153.22 CEP19679.1 - 2.3e-69 229.1 2.5 3.2e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sel1 PF08238.7 CEP19680.1 - 8.4e-39 131.1 13.0 4.6e-07 30.2 0.0 7.3 7 0 0 7 7 7 7 Sel1 repeat Auts2 PF15336.1 CEP19680.1 - 1.8 8.5 6.1 5.7 6.8 0.7 2.3 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein HGD-D PF06050.8 CEP19681.1 - 0.18 10.5 2.0 0.31 9.8 1.3 1.4 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component V_ATPase_I PF01496.14 CEP19681.1 - 0.41 8.4 23.7 0.0073 14.2 4.3 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CobN-Mg_chel PF02514.11 CEP19681.1 - 0.9 6.8 10.6 1.2 6.4 7.3 1.2 1 0 0 1 1 1 0 CobN/Magnesium Chelatase DUF3450 PF11932.3 CEP19681.1 - 4.1 6.6 23.4 0.1 11.8 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 CEP19681.1 - 6.9 6.9 12.4 3.1 8.1 3.5 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein COQ7 PF03232.8 CEP19681.1 - 9.6 5.6 12.5 10 5.5 6.1 2.7 1 1 1 2 2 2 0 Ubiquinone biosynthesis protein COQ7 DUF2404 PF10296.4 CEP19682.1 - 2e-24 85.5 0.0 5.5e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) UpxZ PF06603.6 CEP19682.1 - 0.093 12.7 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists PUA PF01472.15 CEP19683.1 - 8.8e-14 50.9 0.1 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 PUA domain HsbA PF12296.3 CEP19683.1 - 0.064 13.1 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A ADH_zinc_N PF00107.21 CEP19686.1 - 8.5e-22 77.0 0.2 1.3e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEP19686.1 - 6.4e-09 36.7 0.0 1.4e-08 35.6 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEP19686.1 - 1.2e-06 28.2 0.4 4.1e-06 26.5 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MgsA_C PF12002.3 CEP19688.1 - 1.7e-58 197.0 0.1 2.7e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CEP19688.1 - 1.9e-17 63.6 0.0 5e-17 62.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEP19688.1 - 3e-14 52.6 0.0 6.2e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CEP19688.1 - 1.1e-07 31.5 0.0 5.8e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CEP19688.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CEP19688.1 - 1.3e-05 24.6 0.0 0.00032 20.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Rad17 PF03215.10 CEP19688.1 - 3.1e-05 22.8 0.0 0.01 14.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CEP19688.1 - 0.0002 21.4 0.0 0.0038 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CEP19688.1 - 0.00021 21.4 0.3 0.0058 16.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CEP19688.1 - 0.00021 20.1 0.0 0.00045 19.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CEP19688.1 - 0.00039 20.3 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CEP19688.1 - 0.00053 19.2 0.1 0.069 12.3 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CEP19688.1 - 0.00076 19.1 0.1 0.0034 17.0 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 CEP19688.1 - 0.00078 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEP19688.1 - 0.0018 19.0 0.0 0.0052 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CEP19688.1 - 0.002 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CEP19688.1 - 0.0021 17.7 0.1 1.4 8.5 0.0 2.4 1 1 1 2 2 2 2 Archaeal ATPase Viral_helicase1 PF01443.13 CEP19688.1 - 0.0028 17.2 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 CEP19688.1 - 0.004 17.4 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 ABC transporter ResIII PF04851.10 CEP19688.1 - 0.0047 16.7 0.1 1.9 8.2 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CEP19688.1 - 0.0065 16.6 0.0 0.025 14.7 0.0 2.1 3 0 0 3 3 1 1 RNA helicase NB-ARC PF00931.17 CEP19688.1 - 0.0087 14.9 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 CEP19688.1 - 0.01 15.2 0.2 5.1 6.4 0.0 3.0 1 1 1 2 2 2 0 AAA-like domain SKI PF01202.17 CEP19688.1 - 0.016 15.0 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 Shikimate kinase AAA_11 PF13086.1 CEP19688.1 - 0.025 14.1 0.2 0.05 13.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 CEP19688.1 - 0.045 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.15 CEP19688.1 - 0.069 11.8 0.1 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.8 CEP19688.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sgf11 PF08209.6 CEP19688.1 - 0.073 12.3 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) AAA_24 PF13479.1 CEP19688.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CEP19688.1 - 0.088 12.7 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CEP19688.1 - 0.088 12.4 0.0 0.2 11.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 CEP19688.1 - 0.16 10.4 0.1 0.3 9.4 0.0 1.4 2 0 0 2 2 2 0 AAA domain Med11 PF10280.4 CEP19689.1 - 1.2e-07 31.7 0.6 1.7e-07 31.2 0.4 1.3 1 1 0 1 1 1 1 Mediator complex protein Thy1 PF02511.10 CEP19689.1 - 0.036 13.3 0.2 0.052 12.8 0.2 1.3 1 0 0 1 1 1 0 Thymidylate synthase complementing protein DUF4248 PF14053.1 CEP19689.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) ADIP PF11559.3 CEP19689.1 - 0.13 12.1 0.7 3.1 7.6 0.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sec7 PF01369.15 CEP19690.1 - 1.5e-38 132.4 0.1 3.9e-38 131.0 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CEP19690.1 - 2e-14 53.7 0.0 1.8e-12 47.4 0.0 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEP19690.1 - 2.2e-08 34.2 1.5 1.4e-07 31.7 0.6 2.6 1 1 1 2 2 2 1 PH domain HipA_C PF07804.7 CEP19690.1 - 0.066 13.3 0.1 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 HipA-like C-terminal domain Retrotrans_gag PF03732.12 CEP19691.1 - 1.8e-05 24.6 0.3 4.5e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Cytochrom_B558a PF05038.8 CEP19691.1 - 0.18 11.3 0.5 0.43 10.1 0.4 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Macoilin PF09726.4 CEP19691.1 - 1.4 7.1 12.4 3.1 5.9 8.5 1.6 1 1 0 1 1 1 0 Transmembrane protein HORMA PF02301.13 CEP19692.1 - 3.9e-11 42.8 0.3 5.1e-11 42.4 0.2 1.1 1 0 0 1 1 1 1 HORMA domain MDM31_MDM32 PF08118.6 CEP19693.1 - 2.1e-134 448.7 0.1 1.2e-77 261.5 0.0 2.4 2 0 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins CK_II_beta PF01214.13 CEP19696.1 - 1.7e-77 259.1 0.1 2e-77 258.8 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Glyco_hydro_100 PF12899.2 CEP19696.1 - 0.09 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase Kelch_5 PF13854.1 CEP19700.1 - 1.1e-11 44.4 4.2 0.0081 16.1 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 CEP19700.1 - 1e-10 41.3 10.2 0.0064 16.6 0.7 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CEP19700.1 - 7.4e-10 38.4 6.2 0.31 10.8 0.0 6.6 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CEP19700.1 - 8.9e-09 35.2 13.4 0.00024 21.1 0.3 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 CEP19700.1 - 1.2e-08 34.3 5.8 0.0082 15.6 0.2 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CEP19700.1 - 0.0001 21.8 1.5 8.4 6.3 0.1 4.6 4 0 0 4 4 4 2 Kelch motif PPR_2 PF13041.1 CEP19701.1 - 2.1e-30 104.4 7.2 4.6e-12 45.7 0.0 5.8 6 0 0 6 6 6 4 PPR repeat family PPR_3 PF13812.1 CEP19701.1 - 8.7e-19 66.1 5.0 0.0016 18.5 0.0 8.4 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.15 CEP19701.1 - 9.1e-15 53.5 14.5 7.3e-06 25.6 0.0 7.4 9 0 0 9 9 9 3 PPR repeat PPR_1 PF12854.2 CEP19701.1 - 4.5e-11 42.0 14.1 0.00033 20.0 0.0 6.0 7 0 0 7 7 7 3 PPR repeat RPM2 PF08579.6 CEP19701.1 - 0.0032 17.5 8.0 0.25 11.5 0.4 4.3 3 2 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 CEP19701.1 - 0.017 14.0 1.0 0.38 9.5 0.1 2.6 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Foie-gras_1 PF11817.3 CEP19701.1 - 0.037 13.5 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 RPN7 PF10602.4 CEP19701.1 - 0.067 12.5 0.6 0.35 10.2 0.0 2.4 3 0 0 3 3 3 0 26S proteasome subunit RPN7 ATP13 PF12921.2 CEP19701.1 - 0.86 8.9 5.5 0.97 8.7 0.0 3.3 4 0 0 4 4 4 0 Mitochondrial ATPase expression AAA_17 PF13207.1 CEP19702.1 - 1.3e-07 32.4 0.0 3e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEP19702.1 - 1.1e-06 28.9 0.0 3.2e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CEP19702.1 - 0.00017 21.2 0.0 0.00045 19.8 0.0 1.7 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 CEP19702.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CEP19702.1 - 0.014 15.3 0.0 0.03 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEP19702.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter NAD_Gly3P_dh_N PF01210.18 CEP19703.1 - 7.8e-53 178.4 0.1 2.4e-52 176.8 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CEP19703.1 - 2e-52 176.8 0.1 3.6e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CEP19703.1 - 0.00044 20.6 0.3 0.012 16.0 0.2 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 CEP19703.1 - 0.025 14.9 0.0 0.06 13.6 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TRAPPC-Trs85 PF12739.2 CEP19704.1 - 1.1e-94 317.4 9.7 1.2e-92 310.7 2.0 2.6 3 0 0 3 3 3 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.1 CEP19704.1 - 0.026 13.6 1.0 0.18 10.9 0.2 2.1 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 CEP19704.1 - 0.035 14.0 0.3 0.61 10.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cnd3 PF12719.2 CEP19705.1 - 2.1e-54 184.5 12.8 2.7e-37 128.3 0.6 4.4 3 2 1 4 4 4 3 Nuclear condensing complex subunits, C-term domain RabGAP-TBC PF00566.13 CEP19705.1 - 4.8e-20 71.9 4.3 4.8e-20 71.9 3.0 4.4 4 1 0 4 4 4 1 Rab-GTPase-TBC domain HEAT_2 PF13646.1 CEP19705.1 - 4.2e-05 23.7 0.2 0.11 12.8 0.0 4.8 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CEP19705.1 - 6e-05 22.7 4.0 1.4 9.1 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat BUD22 PF09073.5 CEP19705.1 - 0.00078 18.6 5.8 0.00078 18.6 4.0 2.9 3 0 0 3 3 3 2 BUD22 Apis_Csd PF11671.3 CEP19705.1 - 0.44 10.3 2.7 1 9.1 1.9 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein EF1G PF00647.14 CEP19706.1 - 2.2e-44 149.5 0.6 4.3e-44 148.5 0.4 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 CEP19706.1 - 4.6e-10 39.5 0.3 1.5e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEP19706.1 - 6.7e-10 38.8 0.2 1.9e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEP19706.1 - 1.3e-06 28.1 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP19706.1 - 4.7e-06 27.0 0.0 9.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CEP19706.1 - 5e-05 23.4 0.2 0.00015 21.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEP19706.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PAS_9 PF13426.1 CEP19707.1 - 7.3e-31 106.6 0.0 9.6e-15 54.8 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 CEP19707.1 - 2.5e-19 69.1 0.0 2e-14 53.4 0.0 4.1 5 0 0 5 5 5 2 PAS fold PAS PF00989.19 CEP19707.1 - 4.7e-18 65.0 0.0 8e-08 32.0 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.1 CEP19707.1 - 8.8e-14 51.4 0.0 3.5e-09 36.6 0.0 3.4 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 CEP19707.1 - 1e-11 44.8 0.0 9.1e-05 22.4 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 CEP19707.1 - 0.0012 18.6 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain DPPIV_N PF00930.16 CEP19708.1 - 2.4e-52 177.7 6.8 2.4e-52 177.7 4.7 1.8 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CEP19708.1 - 3.7e-30 104.7 0.0 1.3e-29 102.9 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CEP19708.1 - 1.7e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP19708.1 - 1.3e-05 24.8 0.0 3.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEP19708.1 - 5.5e-05 22.9 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CEP19708.1 - 7.8e-05 22.2 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 CEP19708.1 - 0.00029 20.3 0.1 0.001 18.5 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Mucin PF01456.12 CEP19708.1 - 1.5 8.5 28.4 0.057 13.1 14.7 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 CEP19708.1 - 6.9 4.5 15.6 14 3.4 10.8 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RVT_1 PF00078.22 CEP19709.1 - 9.9e-32 110.0 0.0 2.7e-31 108.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP19709.1 - 7.9e-09 35.8 0.5 2e-08 34.5 0.4 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CEP19709.1 - 4.6e-07 30.0 1.0 1.2e-06 28.7 0.7 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 CEP19709.1 - 0.013 15.4 1.2 0.013 15.4 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF4317 PF14199.1 CEP19710.1 - 0.0046 15.8 0.3 0.024 13.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4317) HTH_28 PF13518.1 CEP19711.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Lipoprotein_Ltp PF07553.6 CEP19711.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein MULE PF10551.4 CEP19712.1 - 2.6e-19 69.1 0.2 6.7e-19 67.8 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CEP19712.1 - 0.0044 15.6 0.0 0.0079 14.7 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family FAR1 PF03101.10 CEP19712.1 - 0.16 12.5 0.2 0.16 12.5 0.2 2.8 3 0 0 3 3 3 0 FAR1 DNA-binding domain CRAL_TRIO_2 PF13716.1 CEP19713.1 - 0.03 14.2 0.1 0.076 12.9 0.0 1.6 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain MS_channel PF00924.13 CEP19714.1 - 9.6e-16 57.7 0.3 1.8e-15 56.8 0.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CEP19714.1 - 7.1e-05 21.8 0.3 7.1e-05 21.8 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CEP19714.1 - 0.0015 18.2 0.2 0.0015 18.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CEP19714.1 - 0.0018 18.3 1.7 0.046 13.8 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CEP19714.1 - 0.004 16.4 0.5 0.004 16.4 0.3 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CEP19714.1 - 0.011 15.2 0.1 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Chitin_synth_2 PF03142.10 CEP19715.1 - 1.9e-243 808.6 0.7 2.9e-243 808.0 0.5 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CEP19715.1 - 1.5e-12 47.6 8.6 8.2e-12 45.2 5.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEP19715.1 - 9.9e-11 41.8 0.0 2.9e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CEP19715.1 - 0.0004 20.1 0.0 0.0028 17.3 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 CEP19715.1 - 0.0059 15.9 0.0 0.39 9.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 PAT1 PF09770.4 CEP19715.1 - 3.6 5.6 22.6 5.1 5.2 15.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MSA-2c PF12238.3 CEP19717.1 - 0.00057 19.6 1.9 0.0012 18.5 1.3 1.5 1 1 0 1 1 1 1 Merozoite surface antigen 2c DNA_pol_A_exo1 PF01612.15 CEP19718.1 - 0.00027 20.4 0.0 0.00058 19.3 0.0 1.5 2 0 0 2 2 2 1 3'-5' exonuclease Poxvirus_B22R_C PF13168.1 CEP19719.1 - 0.057 12.6 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Sugar_tr PF00083.19 CEP19720.1 - 2.8e-89 299.7 23.5 1.1e-64 218.6 8.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEP19720.1 - 2e-17 62.9 11.2 2e-17 62.9 7.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily PSI PF01437.20 CEP19720.1 - 2.2e-05 24.5 4.0 3.5e-05 23.8 2.7 1.3 1 0 0 1 1 1 1 Plexin repeat DUF1640 PF07798.6 CEP19720.1 - 0.077 13.0 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) SpdB PF05122.8 CEP19720.1 - 0.25 11.3 2.5 0.63 10.1 1.4 1.8 2 0 0 2 2 2 0 Mobile element transfer protein GST_N_3 PF13417.1 CEP19721.1 - 4.1e-14 52.5 0.0 6.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEP19721.1 - 7e-09 35.4 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CEP19721.1 - 1e-08 35.0 0.1 1.8e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEP19721.1 - 3.2e-06 27.2 0.0 8.4e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEP19721.1 - 2.1e-05 24.3 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEP19721.1 - 0.00054 20.3 0.1 0.0007 20.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AstE_AspA PF04952.9 CEP19722.1 - 1.3e-31 109.6 0.0 6.6e-31 107.2 0.0 2.1 2 1 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.6 CEP19722.1 - 9.2e-26 90.7 0.0 1.8e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 HutD Peptidase_M14 PF00246.19 CEP19722.1 - 5.4e-05 22.9 0.0 0.00018 21.2 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 CEP19722.1 - 0.019 14.0 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Zip PF02535.17 CEP19722.1 - 0.12 11.3 0.1 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Phage_int_SAM_3 PF14659.1 CEP19722.1 - 0.14 12.4 0.1 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Lactamase_B_2 PF12706.2 CEP19723.1 - 6.3e-28 97.6 0.2 1.3e-27 96.6 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEP19723.1 - 1.1e-09 38.2 0.0 9.7e-09 35.1 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Na_Ca_ex PF01699.19 CEP19724.1 - 2.9e-21 75.5 13.1 2.9e-21 75.5 9.1 3.3 2 1 1 3 3 3 2 Sodium/calcium exchanger protein MLANA PF14991.1 CEP19724.1 - 0.065 13.2 0.3 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein melan-A LAB_N PF07578.6 CEP19724.1 - 0.089 12.7 7.5 0.12 12.2 2.5 2.9 1 1 1 2 2 2 0 Lipid A Biosynthesis N-terminal domain Zn_clus PF00172.13 CEP19725.1 - 7e-10 38.6 14.8 1.4e-09 37.7 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_23 PF13476.1 CEP19725.1 - 1.2 9.4 5.9 0.93 9.7 3.1 1.5 2 0 0 2 2 2 0 AAA domain TPMT PF05724.6 CEP19726.1 - 9.6e-35 119.9 0.0 1.7e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.1 CEP19726.1 - 4.3e-05 23.7 0.0 0.00012 22.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP19726.1 - 0.0001 22.8 0.0 0.00047 20.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP19726.1 - 0.00015 21.3 0.0 0.00071 19.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEP19726.1 - 0.00021 21.7 0.0 0.0013 19.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP19726.1 - 0.0004 20.3 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP19726.1 - 0.013 15.9 0.0 0.042 14.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CEP19726.1 - 0.054 13.2 0.0 0.094 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 CEP19727.1 - 2.3e-73 246.0 0.0 3.2e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CEP19727.1 - 2.2e-05 24.4 0.0 6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.10 CEP19727.1 - 0.00028 20.4 0.1 0.00068 19.1 0.0 1.8 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_18 PF12847.2 CEP19727.1 - 0.00045 20.7 0.0 0.0016 18.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TRM PF02005.11 CEP19727.1 - 0.0041 16.0 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 CEP19727.1 - 0.022 14.1 0.0 0.068 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 CEP19727.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Chlam_vir PF05475.6 CEP19729.1 - 0.025 13.7 1.1 0.027 13.6 0.8 1.0 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D Fae PF08714.6 CEP19729.1 - 0.04 13.6 1.8 0.048 13.3 1.2 1.3 1 1 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) RNB PF00773.14 CEP19730.1 - 4.2e-61 207.0 0.1 6.5e-61 206.3 0.0 1.3 1 0 0 1 1 1 1 RNB domain 3HCDH_N PF02737.13 CEP19731.1 - 2.3e-59 200.0 3.4 3.3e-59 199.5 2.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CEP19731.1 - 1.5e-32 111.8 0.1 5.3e-32 110.0 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CEP19731.1 - 9.3e-06 25.5 3.9 0.00027 20.8 2.7 2.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 CEP19731.1 - 1.2e-05 24.9 1.5 4.4e-05 23.1 0.6 2.0 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 CEP19731.1 - 0.00011 22.1 0.1 0.00016 21.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 CEP19731.1 - 0.00012 21.8 0.3 0.00022 20.9 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 CEP19731.1 - 0.0085 15.0 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 CEP19731.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 CEP19731.1 - 0.014 15.7 0.1 0.026 14.8 0.1 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 CEP19731.1 - 0.014 15.6 0.6 0.026 14.7 0.4 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 CEP19731.1 - 0.015 15.6 0.2 0.035 14.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEP19731.1 - 0.023 14.7 0.3 0.038 14.0 0.2 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 CEP19731.1 - 0.031 13.2 0.2 0.045 12.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 CEP19731.1 - 0.086 13.2 2.9 0.58 10.6 2.0 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.1 CEP19731.1 - 0.095 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF89 PF01937.14 CEP19732.1 - 4.9e-112 374.2 2.5 5.7e-112 374.0 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Desulfoferrod_N PF06397.7 CEP19733.1 - 0.043 13.1 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain NAD_binding_6 PF08030.7 CEP19734.1 - 1.1e-15 57.8 0.2 2.6e-13 50.1 0.0 2.6 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CEP19734.1 - 1.1e-14 54.6 6.1 1.1e-14 54.6 4.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CEP19734.1 - 3.3e-06 26.9 0.2 2.1e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 FAD-binding domain DUF504 PF04457.7 CEP19734.1 - 0.05 13.7 0.2 2 8.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF504) Calreticulin PF00262.13 CEP19736.1 - 1.5e-108 362.7 14.6 1.5e-108 362.7 10.1 1.8 2 0 0 2 2 2 1 Calreticulin family DUF4279 PF14106.1 CEP19737.1 - 0.04 13.7 0.1 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DUF1694 PF07997.6 CEP19737.1 - 0.052 13.4 0.2 0.099 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) DinI PF06183.8 CEP19737.1 - 0.083 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 DinI-like family HTH_29 PF13551.1 CEP19738.1 - 1.4e-06 28.3 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP19738.1 - 4.4e-05 22.9 0.1 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CEP19738.1 - 4.7e-05 23.2 0.1 0.00076 19.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP19738.1 - 0.00013 22.7 0.0 0.00043 21.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain NDUF_B4 PF07225.7 CEP19739.1 - 0.077 12.7 0.2 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) OrfB_Zn_ribbon PF07282.6 CEP19739.1 - 0.75 9.4 6.8 1.2 8.7 2.2 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF4611 PF15387.1 CEP19740.1 - 5.5e-05 23.2 17.9 0.95 9.6 0.0 9.9 11 1 1 12 12 12 3 Domain of unknown function (DUF4611) EF-hand_7 PF13499.1 CEP19740.1 - 0.0099 15.9 0.1 0.048 13.7 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain pair Presenilin PF01080.12 CEP19741.1 - 1.3e-71 241.5 2.0 1.8e-71 241.0 1.4 1.1 1 0 0 1 1 1 1 Presenilin PEMT PF04191.8 CEP19742.1 - 7.7e-34 115.9 4.0 7.7e-34 115.9 2.8 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase RNA_capsid PF03035.9 CEP19743.1 - 0.024 14.4 0.9 0.034 13.9 0.6 1.2 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein DUF2397 PF09660.5 CEP19743.1 - 0.034 12.7 0.0 0.056 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF3439 PF11921.3 CEP19745.1 - 0.21 11.3 5.9 0.38 10.5 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CEP19745.1 - 4.8 5.0 9.5 6.7 4.5 6.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ank_2 PF12796.2 CEP19746.1 - 3.3e-24 85.0 5.1 1.2e-11 44.7 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEP19746.1 - 8.8e-19 66.3 12.3 9.2e-09 34.6 0.1 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 CEP19746.1 - 1.1e-17 62.3 5.6 2.2e-06 27.3 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CEP19746.1 - 2.1e-17 62.7 6.1 1.6e-09 37.6 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEP19746.1 - 1.6e-15 57.0 4.3 1.7e-06 28.3 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) LNP1 PF15419.1 CEP19746.1 - 0.045 13.8 4.3 0.1 12.6 3.0 1.7 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 YqzL PF14006.1 CEP19749.1 - 0.094 12.9 0.4 0.23 11.6 0.1 1.8 2 1 0 2 2 2 0 YqzL-like protein VirE2 PF07229.7 CEP19749.1 - 0.13 10.5 5.0 0.14 10.5 3.5 1.0 1 0 0 1 1 1 0 VirE2 WD40 PF00400.27 CEP19750.1 - 2.6e-33 112.6 5.7 1.4e-12 46.9 0.6 3.1 2 1 1 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 CEP19750.1 - 1e-05 25.3 0.1 0.00011 21.9 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CEP19750.1 - 0.021 13.6 0.5 0.2 10.3 0.3 1.9 1 1 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.3 CEP19750.1 - 0.033 12.3 0.6 0.073 11.1 0.2 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 WD40 PF00400.27 CEP19751.1 - 5.8e-13 48.1 0.5 1.1e-11 44.0 0.2 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat MULE PF10551.4 CEP19751.1 - 0.07 13.2 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 MULE transposase domain Cytochrom_B562 PF07361.6 CEP19752.1 - 0.0045 17.3 0.3 0.0072 16.7 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b562 Cep57_MT_bd PF06657.8 CEP19752.1 - 0.01 15.7 2.8 0.017 15.0 1.9 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Cluap1 PF10234.4 CEP19752.1 - 0.016 14.4 1.7 0.019 14.1 1.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Phlebovirus_NSM PF07246.6 CEP19752.1 - 0.064 12.3 0.7 0.092 11.8 0.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M V_ATPase_I PF01496.14 CEP19752.1 - 0.073 10.9 0.7 0.08 10.7 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec8_exocyst PF04048.9 CEP19752.1 - 0.13 11.8 3.4 0.2 11.2 2.1 1.4 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Atg14 PF10186.4 CEP19752.1 - 0.24 10.2 9.4 0.051 12.5 4.1 1.5 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 CEP19752.1 - 0.36 10.6 8.6 0.56 10.0 6.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-C4pol PF14260.1 CEP19752.1 - 0.36 10.8 2.6 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta IncA PF04156.9 CEP19752.1 - 0.59 9.6 7.8 0.82 9.2 5.4 1.2 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 CEP19752.1 - 1.1 9.6 10.6 2.1 8.6 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 CEP19752.1 - 3.3 7.7 7.2 2.6 8.0 3.7 1.8 2 1 0 2 2 2 0 TSC-22/dip/bun family Rubis-subs-bind PF09273.6 CEP19753.1 - 0.12 12.2 0.9 0.23 11.3 0.6 1.5 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding zf-C2H2 PF00096.21 CEP19755.1 - 0.018 15.3 1.8 0.049 13.9 1.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CEP19755.1 - 0.092 12.8 1.4 0.33 11.0 0.3 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CEP19755.1 - 0.13 12.6 1.1 0.44 10.9 0.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-LYAR PF08790.6 CEP19755.1 - 0.31 10.7 4.2 0.17 11.5 0.7 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger HTH_23 PF13384.1 CEP19756.1 - 5e-08 32.3 0.0 7.2e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.1 CEP19756.1 - 1.4e-07 31.3 0.0 1.5e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 CEP19756.1 - 1.3e-05 25.3 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.1 CEP19756.1 - 0.00038 20.5 0.1 0.014 15.5 0.0 2.2 1 1 1 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 CEP19756.1 - 0.0015 19.2 0.0 0.0064 17.2 0.0 2.0 2 1 0 2 2 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 CEP19756.1 - 0.0023 17.9 0.0 0.0046 16.9 0.0 1.7 1 1 0 1 1 1 1 Transposase HTH_Tnp_1 PF01527.15 CEP19756.1 - 0.0032 17.4 0.1 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Transposase LZ_Tnp_IS481 PF13011.1 CEP19756.1 - 0.035 14.4 0.1 0.094 13.0 0.0 1.7 2 1 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.1 CEP19756.1 - 0.055 12.6 0.1 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 FUR PF01475.14 CEP19756.1 - 0.077 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_30 PF13556.1 CEP19756.1 - 0.11 12.0 0.0 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_36 PF13730.1 CEP19756.1 - 0.13 12.4 0.1 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 CEP19757.1 - 0.0003 20.3 0.0 0.00058 19.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CEP19757.1 - 0.0032 17.4 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 CEP19757.1 - 0.02 14.0 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Aldedh PF00171.17 CEP19758.1 - 3e-165 550.0 1.2 3.4e-165 549.8 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CEP19758.1 - 0.084 12.0 0.0 0.83 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Melibiase PF02065.13 CEP19759.1 - 5.4e-21 74.7 1.0 1.1e-20 73.7 0.7 1.4 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 CEP19759.1 - 6.2e-11 41.7 0.2 8.8e-11 41.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GHL6 PF14871.1 CEP19759.1 - 0.02 14.8 0.1 2.7 7.9 0.0 3.2 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 6 Glyco_hydro_18 PF00704.23 CEP19760.1 - 6.2e-16 58.7 0.0 7.3e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fer4_12 PF13353.1 CEP19760.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain zf-UBP PF02148.14 CEP19761.1 - 6e-19 67.9 4.9 2.2e-18 66.1 3.4 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 CEP19761.1 - 3.2e-18 65.2 0.1 7.9e-18 64.0 0.1 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 Cortex-I_coil PF09304.5 CEP19761.1 - 6.6e-05 22.9 13.3 0.0002 21.3 9.2 1.9 1 0 0 1 1 1 1 Cortexillin I, coiled coil RRM_6 PF14259.1 CEP19761.1 - 0.0003 20.7 0.0 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEP19761.1 - 0.021 14.4 0.0 0.058 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2967 PF11179.3 CEP19761.1 - 0.083 12.3 1.4 0.25 10.8 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RRM_5 PF13893.1 CEP19761.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ApoO PF09769.4 CEP19761.1 - 0.13 11.9 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein O F-box-like PF12937.2 CEP19762.1 - 2.4e-07 30.3 1.1 1.6e-06 27.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEP19762.1 - 0.00092 18.8 0.2 0.0028 17.2 0.1 1.9 1 0 0 1 1 1 1 F-box domain NADH-u_ox-rdase PF10785.4 CEP19763.1 - 1.9e-30 104.9 0.4 2.6e-30 104.4 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 CEP19763.1 - 1.2e-21 76.1 0.1 1.7e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Peptidase_C13 PF01650.13 CEP19764.1 - 3.7e-45 154.2 0.6 4.7e-45 153.8 0.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF1230 PF06799.6 CEP19764.1 - 0.089 12.6 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) PDEase_I PF00233.14 CEP19765.1 - 1e-56 192.3 0.0 1.2e-55 188.8 0.0 2.4 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.19 CEP19765.1 - 2.6e-06 27.3 0.0 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Mt_ATP-synt_B PF05405.9 CEP19765.1 - 0.0068 15.8 1.1 0.7 9.3 0.2 2.4 2 0 0 2 2 2 2 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Microtub_assoc PF07989.6 CEP19766.1 - 1e-09 38.0 7.9 1.8e-09 37.2 5.5 1.4 1 0 0 1 1 1 1 Microtubule associated Leu_zip PF15294.1 CEP19766.1 - 0.011 14.9 1.0 0.015 14.4 0.7 1.2 1 0 0 1 1 1 0 Leucine zipper EPL1 PF10513.4 CEP19766.1 - 0.072 13.3 1.1 0.095 12.9 0.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Lipoprotein_20 PF13942.1 CEP19766.1 - 0.16 11.5 2.5 0.27 10.7 1.7 1.4 1 0 0 1 1 1 0 YfhG lipoprotein Takusan PF04822.8 CEP19766.1 - 0.55 10.0 5.8 0.91 9.3 2.7 2.3 2 1 0 2 2 2 0 Takusan bZIP_1 PF00170.16 CEP19766.1 - 1.1 9.3 5.6 1.2 9.0 0.2 2.4 1 1 1 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.1 CEP19766.1 - 1.4 8.9 8.3 0.18 11.7 2.7 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 CEP19766.1 - 3.8 7.0 6.6 8.9 5.8 1.4 2.2 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.20 CEP19767.1 - 2.3e-70 236.7 0.0 3.1e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19767.1 - 3.2e-32 111.6 0.0 4.7e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CEP19767.1 - 1.1e-09 38.6 4.7 3.5e-09 37.0 3.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEP19767.1 - 0.00048 19.1 0.0 0.0018 17.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CEP19767.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CEP19767.1 - 0.15 11.1 0.1 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Urm1 PF09138.6 CEP19768.1 - 5.8e-36 122.5 0.6 6.4e-36 122.3 0.4 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CEP19768.1 - 4.8e-05 23.7 0.0 5.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ThiS family Per1 PF04080.8 CEP19768.1 - 0.0077 15.6 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Per1-like Stap_Strp_tox_C PF02876.12 CEP19768.1 - 0.03 14.4 0.2 0.036 14.2 0.1 1.1 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain DUF3290 PF11694.3 CEP19768.1 - 0.056 13.1 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) NAD_binding_10 PF13460.1 CEP19769.1 - 1.4e-40 139.2 0.0 1.6e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEP19769.1 - 2e-05 23.9 0.2 3.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 CEP19769.1 - 0.00055 19.8 0.1 0.00098 19.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 CEP19769.1 - 0.00074 19.9 0.3 0.0014 19.0 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 CEP19769.1 - 0.00076 18.9 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CEP19769.1 - 0.01 14.7 0.2 0.062 12.1 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain DFP PF04127.10 CEP19769.1 - 0.016 14.8 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Semialdhyde_dh PF01118.19 CEP19769.1 - 0.02 15.1 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 CEP19769.1 - 0.055 13.6 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain 3HCDH_N PF02737.13 CEP19769.1 - 0.094 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cyclin_N PF00134.18 CEP19770.1 - 1.3e-15 57.0 0.0 1.7e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CEP19770.1 - 4.6e-10 40.1 0.0 5.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin EXS PF03124.9 CEP19771.1 - 1.1e-89 300.8 26.4 1.4e-89 300.4 18.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CEP19771.1 - 1.1e-44 153.2 8.3 1.1e-44 153.2 5.7 2.0 2 1 0 2 2 2 1 SPX domain Xan_ur_permease PF00860.15 CEP19772.1 - 2.2e-83 279.9 39.4 2.8e-83 279.5 27.3 1.1 1 0 0 1 1 1 1 Permease family Got1 PF04178.7 CEP19773.1 - 9.6e-19 67.6 18.5 1.2e-18 67.2 12.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family TFIIA PF03153.8 CEP19775.1 - 5.1 6.8 13.9 7.2 6.4 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDE_Tnp_1_7 PF13843.1 CEP19776.1 - 1.3e-45 155.9 0.1 1.5e-45 155.7 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.16 CEP19776.1 - 0.018 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Rho_GDI PF02115.12 CEP19778.1 - 0.064 12.6 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Orbi_VP5 PF00901.12 CEP19778.1 - 0.076 11.2 1.5 0.094 10.9 1.1 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF342 PF03961.8 CEP19778.1 - 0.077 11.3 0.9 0.088 11.2 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pox_polyA_pol_N PF12630.2 CEP19778.1 - 0.11 12.6 0.4 0.17 12.0 0.2 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Chromo PF00385.19 CEP19779.1 - 0.008 15.8 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 CEP19781.1 - 2.4e-05 23.5 0.1 3.8e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Transposase family tnp2 TLP-20 PF06088.6 CEP19781.1 - 0.028 14.0 0.1 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HTH_11 PF08279.7 CEP19781.1 - 0.15 11.7 0.1 16 5.2 0.0 2.5 2 0 0 2 2 2 0 HTH domain Pkinase PF00069.20 CEP19782.1 - 6e-54 182.9 0.0 6e-32 110.8 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19782.1 - 3.4e-27 95.1 0.0 1.6e-18 66.7 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Response_reg PF00072.19 CEP19782.1 - 7.9e-16 58.0 0.3 2.6e-15 56.3 0.2 2.0 1 0 0 1 1 1 1 Response regulator receiver domain C2 PF00168.25 CEP19783.1 - 1.1e-08 34.8 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain TrbE PF11100.3 CEP19784.1 - 0.061 13.1 2.2 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Conjugal transfer protein TrbE RVT_1 PF00078.22 CEP19785.1 - 2.2e-05 23.8 0.0 3.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEP19786.1 - 6.8e-24 84.4 0.2 9.2e-24 83.9 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP20 PF00011.16 CEP19789.1 - 8.7e-18 64.0 0.1 1.6e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Taeniidae_ag PF05596.6 CEP19789.1 - 3.6e-16 58.7 0.0 0.019 14.7 0.0 7.1 4 2 3 7 7 7 4 Taeniidae antigen CBM_19 PF03427.8 CEP19789.1 - 5.6e-08 32.4 12.6 1.7 8.4 0.0 6.9 7 1 0 7 7 7 4 Carbohydrate binding domain (family 19) BON PF04972.12 CEP19789.1 - 0.0039 16.9 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 BON domain PARP_reg PF02877.9 CEP19789.1 - 0.024 14.3 0.2 2.2 7.9 0.0 3.3 1 1 1 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain Me-amine-dh_L PF02975.9 CEP19789.1 - 0.48 10.4 3.7 8.7 6.3 0.0 3.6 4 1 0 4 4 4 0 Methylamine dehydrogenase, L chain zf-C3Hc3H PF13891.1 CEP19789.1 - 3.6 7.7 21.1 0.19 11.8 0.5 5.6 6 0 0 6 6 6 0 Potential DNA-binding domain adh_short_C2 PF13561.1 CEP19790.1 - 8.5e-32 110.8 0.1 1e-31 110.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEP19790.1 - 1.7e-25 89.8 1.6 2.2e-25 89.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEP19790.1 - 1.7e-13 50.5 0.5 2.5e-13 50.1 0.4 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 CEP19790.1 - 0.022 13.7 0.1 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 CEP19790.1 - 0.054 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent His_biosynth PF00977.16 CEP19790.1 - 0.085 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Sec23_trunk PF04811.10 CEP19791.1 - 7.3e-60 202.3 0.0 1.3e-59 201.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 CEP19791.1 - 5.6e-15 54.6 2.7 1.3e-14 53.4 1.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CEP19791.1 - 1.9e-13 50.7 0.0 4.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CEP19791.1 - 3.3e-12 45.7 0.1 6.8e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 CEP19791.1 - 2.3e-10 39.9 0.0 6e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Fer2_3 PF13085.1 CEP19792.1 - 3.5e-32 110.5 0.1 5.8e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CEP19792.1 - 5.4e-10 39.4 8.0 5.4e-10 39.4 5.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CEP19792.1 - 3.4e-08 33.3 5.8 3.4e-08 33.3 4.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CEP19792.1 - 0.00016 21.4 5.6 0.00016 21.4 3.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CEP19792.1 - 0.00034 20.9 2.7 0.00034 20.9 1.9 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CEP19792.1 - 0.0016 18.8 5.7 0.0016 18.8 3.9 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CEP19792.1 - 0.0029 17.8 10.9 0.045 14.0 0.5 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 CEP19792.1 - 0.0052 16.5 0.4 0.0052 16.5 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 CEP19792.1 - 2.3 8.8 6.8 1.2 9.8 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain HATPase_c PF02518.21 CEP19793.1 - 4.4e-24 84.3 0.2 8.8e-24 83.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CEP19793.1 - 5.3e-21 74.3 0.1 1.2e-20 73.2 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 CEP19793.1 - 1.5e-18 66.6 0.1 1.2e-11 44.4 0.1 2.6 2 0 0 2 2 2 2 PAS fold Response_reg PF00072.19 CEP19793.1 - 5.9e-17 61.6 0.0 7.7e-16 58.0 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.5 CEP19793.1 - 3.2e-16 59.3 0.0 2.9e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 CEP19793.1 - 7.1e-16 58.4 0.0 1.8e-11 44.3 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 CEP19793.1 - 6.1e-11 42.0 0.0 9.9e-08 31.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 CEP19793.1 - 0.0021 17.8 0.0 0.028 14.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain Aminotran_3 PF00202.16 CEP19794.1 - 3e-97 325.5 0.0 2.6e-95 319.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CEP19794.1 - 0.061 12.2 0.0 0.35 9.7 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II Aldo_ket_red PF00248.16 CEP19795.1 - 1e-80 270.6 0.0 1.2e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.9 CEP19795.1 - 0.021 14.5 0.2 1.6 8.5 0.4 2.9 2 1 0 2 2 2 0 NAF domain Syd PF07348.7 CEP19797.1 - 0.00069 18.9 4.9 0.0012 18.2 3.2 1.6 1 1 0 1 1 1 1 Syd protein (SUKH-2) Cas_Cas1 PF01867.11 CEP19797.1 - 0.017 14.2 1.0 0.028 13.4 0.2 1.8 1 1 1 2 2 2 0 CRISPR associated protein Cas1 CBF PF03914.12 CEP19798.1 - 1.1e-43 148.5 2.4 2.4e-43 147.4 1.7 1.6 1 0 0 1 1 1 1 CBF/Mak21 family Velvet PF11754.3 CEP19799.1 - 3.7e-52 176.8 4.4 2.4e-51 174.2 3.1 2.3 1 1 0 1 1 1 1 Velvet factor MMR_HSR1 PF01926.18 CEP19800.1 - 3.7e-21 75.2 0.0 9.1e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP19800.1 - 1.2e-06 27.9 0.4 1.9e-06 27.2 0.2 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 CEP19800.1 - 1.7e-05 24.2 0.4 2.8e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 CEP19800.1 - 1.9e-05 24.1 1.5 0.0002 20.8 1.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CEP19800.1 - 7.9e-05 22.5 0.6 0.0096 15.7 0.2 2.7 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 CEP19800.1 - 0.00011 21.4 0.0 0.00095 18.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CEP19800.1 - 0.00014 21.3 0.1 0.00025 20.5 0.1 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CEP19800.1 - 0.00014 22.3 0.1 0.00046 20.6 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 CEP19800.1 - 0.0018 17.3 2.6 0.44 9.5 1.8 2.7 1 1 0 1 1 1 1 Septin MobB PF03205.9 CEP19800.1 - 0.0037 16.9 0.6 0.043 13.5 0.0 2.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 CEP19800.1 - 0.0053 15.9 1.3 0.0087 15.1 0.0 1.8 2 1 0 2 2 2 1 AIG1 family SRPRB PF09439.5 CEP19800.1 - 0.0067 15.6 0.0 0.019 14.1 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 CEP19800.1 - 0.028 14.7 0.0 0.059 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Hydrolase_6 PF13344.1 CEP19800.1 - 9.8 6.1 6.5 2.7 7.9 0.2 3.0 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase TrmE_N PF10396.4 CEP19801.1 - 2.9e-39 133.5 0.0 1.1e-38 131.7 0.0 2.0 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 CEP19801.1 - 1.5e-20 73.2 0.0 3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEP19801.1 - 2.3e-09 36.7 0.2 2.3e-08 33.4 0.1 2.5 1 1 1 2 2 2 1 Ferrous iron transport protein B AAA_17 PF13207.1 CEP19801.1 - 3.3e-06 27.9 0.1 1.3e-05 25.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain Dynamin_N PF00350.18 CEP19801.1 - 4.2e-06 26.6 0.0 7.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 CEP19801.1 - 7.8e-05 23.1 0.0 0.00053 20.4 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 CEP19801.1 - 0.00012 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CEP19801.1 - 0.00012 20.9 1.8 0.45 9.2 0.0 3.2 2 1 1 3 3 3 2 ArgK protein AAA_18 PF13238.1 CEP19801.1 - 0.00039 20.7 0.0 0.00084 19.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CEP19801.1 - 0.00075 19.0 0.0 0.005 16.3 0.0 2.2 2 1 0 2 2 2 1 AAA-like domain GTP_EFTU PF00009.22 CEP19801.1 - 0.00076 18.9 0.1 0.2 11.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEP19801.1 - 0.001 18.2 0.0 0.0023 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTPase_Cys_C PF12631.2 CEP19801.1 - 0.002 18.4 0.1 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE AAA_33 PF13671.1 CEP19801.1 - 0.0021 17.9 0.1 0.032 14.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 CEP19801.1 - 0.0033 17.0 0.0 4.1 6.8 0.0 3.2 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CEP19801.1 - 0.0034 16.8 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CEP19801.1 - 0.0035 16.8 0.2 0.16 11.4 0.0 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CEP19801.1 - 0.0044 17.3 0.1 0.0088 16.3 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 CEP19801.1 - 0.013 15.4 0.0 0.066 13.1 0.0 2.2 2 1 1 3 3 2 0 AAA domain AAA_22 PF13401.1 CEP19801.1 - 0.013 15.6 0.0 0.089 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 CEP19801.1 - 0.015 14.5 0.1 0.056 12.6 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.17 CEP19801.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Ras family MobB PF03205.9 CEP19801.1 - 0.041 13.5 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CEP19801.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CEP19801.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain 4HB_MCP_1 PF12729.2 CEP19802.1 - 0.051 12.9 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction WIF PF02019.13 CEP19803.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 WIF domain Aldo_ket_red PF00248.16 CEP19805.1 - 3.9e-36 124.3 0.4 4.6e-36 124.1 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNARE PF05739.14 CEP19806.1 - 1.6e-06 27.6 15.2 4.9e-06 26.1 0.3 3.9 4 0 0 4 4 4 2 SNARE domain V-SNARE_C PF12352.3 CEP19806.1 - 0.0011 18.9 4.5 0.054 13.5 0.1 3.0 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.7 CEP19806.1 - 0.0065 16.7 0.8 0.0065 16.7 0.5 2.9 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Vip3A_N PF12495.3 CEP19806.1 - 4.8 6.8 7.8 5.2 6.7 2.5 2.6 2 1 0 2 2 2 0 Vegetative insecticide protein 3A N terminal Laminin_II PF06009.7 CEP19806.1 - 8.1 6.2 13.6 1 9.0 0.2 2.7 3 0 0 3 3 3 0 Laminin Domain II PC_rep PF01851.17 CEP19807.1 - 3.3e-30 102.6 23.0 2.4e-06 27.4 0.0 9.0 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CEP19807.1 - 0.00017 21.7 0.3 0.59 10.4 0.1 3.7 3 0 0 3 3 3 2 HEAT repeats RNase_P_p30 PF01876.11 CEP19807.1 - 0.087 12.0 0.1 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit p30 DUF935 PF06074.7 CEP19807.1 - 1.3 7.6 7.7 2.2 6.8 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF4175 PF13779.1 CEP19807.1 - 4.9 4.7 10.3 7.3 4.1 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Vfa1 PF08432.5 CEP19807.1 - 5.8 6.8 15.0 11 5.9 10.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Glyco_transf_15 PF01793.11 CEP19808.1 - 3.5e-231 765.7 25.4 6.7e-129 429.5 4.0 2.7 2 1 1 3 3 3 2 Glycolipid 2-alpha-mannosyltransferase VID27 PF08553.5 CEP19809.1 - 1.6e-96 324.3 2.5 5.1e-96 322.6 1.8 1.6 1 1 0 1 1 1 1 VID27 cytoplasmic protein Evr1_Alr PF04777.8 CEP19810.1 - 8.6e-22 76.8 0.5 1.9e-21 75.7 0.4 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Ank_2 PF12796.2 CEP19811.1 - 2.2e-29 101.6 7.2 1.3e-13 51.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEP19811.1 - 6.2e-21 73.0 2.5 6.2e-05 22.5 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CEP19811.1 - 1.5e-18 66.7 7.4 6.5e-07 29.7 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEP19811.1 - 1.1e-16 59.2 3.6 0.00074 19.5 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CEP19811.1 - 1.7e-12 47.1 5.7 0.016 15.4 0.0 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) DUF2431 PF10354.4 CEP19812.1 - 8.3e-46 155.9 0.0 4.3e-45 153.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) TFCD_C PF12612.3 CEP19812.1 - 9.8e-44 149.0 0.2 6e-43 146.5 0.1 2.6 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 CEP19812.1 - 6.8e-06 26.2 3.1 0.16 12.2 0.0 5.1 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.17 CEP19812.1 - 7.1e-06 25.6 5.4 0.0037 17.2 0.0 6.1 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.2 CEP19812.1 - 0.00085 19.6 0.1 3.6 8.0 0.0 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CEP19812.1 - 0.0016 18.8 7.4 0.21 12.1 0.0 6.2 6 2 2 8 8 8 1 HEAT-like repeat Kinesin PF00225.18 CEP19813.1 - 1.6e-91 306.4 0.3 1.6e-91 306.4 0.2 2.9 2 1 0 2 2 2 1 Kinesin motor domain EmrE PF13536.1 CEP19814.1 - 0.74 10.0 5.3 0.95 9.6 3.7 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Aa_trans PF01490.13 CEP19815.1 - 5e-56 189.9 27.6 6.3e-55 186.3 19.2 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CEP19815.1 - 2.1e-09 36.4 31.0 1.2e-08 33.9 21.5 1.9 1 1 0 1 1 1 1 Amino acid permease rve PF00665.21 CEP19816.1 - 3.8e-21 75.3 0.0 1.2e-20 73.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CEP19816.1 - 1.3e-20 73.6 0.1 2.8e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CEP19816.1 - 4.3e-14 51.9 0.6 1.1e-13 50.5 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP19816.1 - 0.0064 15.8 0.0 0.021 14.2 0.0 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Retrotrans_gag PF03732.12 CEP19817.1 - 0.0007 19.6 2.2 0.00081 19.4 0.2 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Fmp27_WPPW PF10359.4 CEP19818.1 - 0.015 13.7 0.6 0.017 13.5 0.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PRP3 PF08572.5 CEP19818.1 - 0.028 13.7 0.6 0.031 13.6 0.4 1.1 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Caldesmon PF02029.10 CEP19818.1 - 0.029 12.8 0.6 0.032 12.6 0.4 1.1 1 0 0 1 1 1 0 Caldesmon PAPA-1 PF04795.7 CEP19818.1 - 0.056 14.1 1.4 0.074 13.7 1.0 1.3 1 0 0 1 1 1 0 PAPA-1-like conserved region DUF2992 PF11208.3 CEP19818.1 - 0.5 10.2 3.6 5.7 6.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) HTH_28 PF13518.1 CEP19819.1 - 2.4e-06 27.4 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CEP19819.1 - 0.00026 20.5 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 CEP19819.1 - 0.00052 19.9 0.0 0.0006 19.7 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 CEP19819.1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_30 PF13556.1 CEP19819.1 - 0.0061 16.1 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain BrkDBD PF09607.5 CEP19819.1 - 0.0071 15.8 0.7 0.013 15.0 0.3 1.6 1 1 0 1 1 1 1 Brinker DNA-binding domain LZ_Tnp_IS481 PF13011.1 CEP19819.1 - 0.009 16.3 0.1 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 Sigma70_r4_2 PF08281.7 CEP19819.1 - 0.018 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.2 CEP19819.1 - 0.024 14.8 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-rbx1 PF12678.2 CEP19819.1 - 0.049 13.7 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger HTH_Tnp_ISL3 PF13542.1 CEP19819.1 - 0.11 11.7 0.1 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 SOBP PF15279.1 CEP19820.1 - 0.2 12.0 5.7 0.24 11.7 3.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Malate_DH PF12434.3 CEP19820.1 - 4.4 7.0 7.0 0.33 10.6 1.2 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Daxx PF03344.10 CEP19821.1 - 0.024 13.1 33.0 0.028 12.9 22.9 1.1 1 0 0 1 1 1 0 Daxx Family SprA-related PF12118.3 CEP19821.1 - 0.043 13.1 23.6 0.056 12.7 16.4 1.1 1 0 0 1 1 1 0 SprA-related family TMEM51 PF15345.1 CEP19821.1 - 0.35 10.5 14.3 0.44 10.2 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Corona_nucleoca PF00937.13 CEP19821.1 - 0.76 8.6 13.0 0.89 8.4 9.0 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ORC6 PF05460.8 CEP19821.1 - 1.5 7.8 18.9 2 7.4 13.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BUD22 PF09073.5 CEP19821.1 - 2.6 7.0 46.9 3.3 6.6 32.5 1.0 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.5 CEP19821.1 - 2.6 7.1 38.0 3 6.9 26.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 CEP19821.1 - 3.2 5.5 45.9 4 5.2 31.8 1.0 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.4 CEP19821.1 - 5.4 5.1 14.1 5.8 5.0 9.8 1.0 1 0 0 1 1 1 0 Transmembrane protein SDA1 PF05285.7 CEP19821.1 - 5.6 6.1 40.6 7.7 5.7 28.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 CEP19821.1 - 7.6 4.4 32.7 11 3.8 22.7 1.3 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.11 CEP19823.1 - 0.2 10.2 4.8 0.21 10.1 3.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FNIP_N PF14636.1 CEP19823.1 - 0.39 11.1 7.1 0.43 11.0 4.9 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus FimP PF09766.4 CEP19823.1 - 0.53 9.2 9.8 0.56 9.2 6.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein BBS2_C PF14782.1 CEP19823.1 - 1.1 7.7 8.7 1.3 7.5 6.0 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Peptidase_U57 PF05582.7 CEP19823.1 - 1.5 7.7 4.5 1.5 7.7 3.1 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Bud13 PF09736.4 CEP19823.1 - 1.6 8.9 10.5 1.9 8.7 7.3 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2547 PF10818.3 CEP19823.1 - 2.5 8.8 9.4 2.9 8.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) DUF3043 PF11241.3 CEP19823.1 - 8.1 5.9 7.0 10 5.6 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) AAA_32 PF13654.1 CEP19824.1 - 0.0039 15.9 2.7 0.0039 15.9 1.9 1.4 1 1 0 1 1 1 1 AAA domain YflT PF11181.3 CEP19824.1 - 0.2 11.8 4.9 6.1 7.0 0.5 2.6 2 0 0 2 2 2 0 Heat induced stress protein YflT Cnd1_N PF12922.2 CEP19824.1 - 3.7 7.1 6.5 0.36 10.4 0.5 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF3659 PF12396.3 CEP19825.1 - 3.6e-97 318.0 51.3 1.2e-17 63.2 2.4 7.5 7 0 0 7 7 7 7 Protein of unknown function (DUF3659) DUF883 PF05957.8 CEP19825.1 - 0.0044 17.3 10.0 0.0044 17.3 6.9 3.6 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF883) RNB PF00773.14 CEP19826.1 - 7.5e-98 327.7 0.1 1e-97 327.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CEP19826.1 - 2.9e-11 43.5 0.2 6.4e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 PIN domain Homeobox PF00046.24 CEP19827.1 - 9.3e-19 66.8 2.6 2e-18 65.7 1.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEP19827.1 - 0.024 14.3 0.2 0.079 12.6 0.2 1.9 1 0 0 1 1 1 0 Homeobox KN domain Diphthamide_syn PF01866.12 CEP19828.1 - 5.1e-73 246.0 2.4 6.9e-42 143.7 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein DDE_3 PF13358.1 CEP19829.1 - 1.9e-36 125.0 0.0 6.7e-36 123.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 CEP19829.1 - 2.7e-05 23.4 0.0 4.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 CEP19829.1 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CEP19829.1 - 0.0079 15.8 0.1 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.21 CEP19829.1 - 0.014 15.5 0.0 0.045 13.8 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain HTH_17 PF12728.2 CEP19829.1 - 0.063 13.5 0.0 0.73 10.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain zf-RVT PF13966.1 CEP19830.1 - 0.00043 20.5 0.4 0.0012 19.1 0.3 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF445 PF04286.7 CEP19831.1 - 0.52 9.7 24.8 0.05 13.1 5.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DDE_3 PF13358.1 CEP19832.1 - 3.7e-08 33.2 0.0 5.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FHA PF00498.21 CEP19833.1 - 1.7e-13 50.4 0.0 3.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF1777 PF08648.7 CEP19833.1 - 0.00026 20.7 42.6 0.00037 20.2 29.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CEP19833.1 - 0.76 8.1 12.8 0.86 7.9 8.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF936 PF06075.7 CEP19833.1 - 4.7 6.0 14.0 5.2 5.8 9.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) C2 PF00168.25 CEP19834.1 - 3.9e-08 33.0 0.0 7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Carn_acyltransf PF00755.15 CEP19835.1 - 4.8e-155 516.9 0.0 5.5e-155 516.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ricin_B_lectin PF00652.17 CEP19838.1 - 1.1e-62 209.6 20.2 7.2e-08 32.5 0.0 14.6 10 7 3 13 13 13 12 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CEP19838.1 - 1.9e-34 118.2 34.0 0.00011 22.5 0.5 12.8 11 3 3 14 14 14 11 Ricin-type beta-trefoil lectin domain-like DUF1317 PF07026.6 CEP19838.1 - 0.15 11.9 1.2 2.4 8.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1317) OPA3 PF07047.7 CEP19839.1 - 1.6e-34 118.5 1.4 1.6e-34 118.5 0.3 1.4 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) IncA PF04156.9 CEP19839.1 - 0.0028 17.2 1.2 0.0037 16.8 0.8 1.2 1 0 0 1 1 1 1 IncA protein Baculo_p47 PF05112.7 CEP19839.1 - 0.013 14.9 0.3 0.022 14.1 0.2 1.3 1 1 0 1 1 1 0 Baculovirus P47 protein Mod_r PF07200.8 CEP19839.1 - 0.035 14.0 4.1 0.053 13.4 2.8 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Rab5-bind PF09311.6 CEP19839.1 - 0.046 13.6 6.1 0.065 13.1 4.2 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Herpes_UL14 PF03580.9 CEP19839.1 - 0.075 12.8 4.1 0.099 12.4 2.1 1.6 1 1 1 2 2 2 0 Herpesvirus UL14-like protein Dynamin_N PF00350.18 CEP19839.1 - 0.096 12.5 0.1 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin family Phage_int_SAM_2 PF12834.2 CEP19839.1 - 0.14 12.5 2.0 10 6.5 0.6 2.5 2 1 0 2 2 2 0 Phage integrase, N-terminal DUF972 PF06156.8 CEP19839.1 - 0.14 12.4 2.6 0.27 11.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HisKA PF00512.20 CEP19839.1 - 0.64 10.0 3.9 6.6 6.8 2.7 2.1 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain NYD-SP28_assoc PF14775.1 CEP19839.1 - 1.2 8.8 10.7 1.7 8.4 0.4 2.3 1 1 1 2 2 2 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 CEP19839.1 - 1.5 8.7 10.0 4 7.3 0.5 2.3 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 CEP19839.1 - 6 6.9 7.7 16 5.5 1.1 2.4 1 1 1 2 2 2 0 bZIP transcription factor GATase_2 PF00310.16 CEP19840.1 - 1.4e-28 99.6 0.0 3.4e-22 78.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CEP19840.1 - 1.9e-18 66.7 0.0 4.1e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CEP19840.1 - 5e-15 55.3 0.0 1.4e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CEP19840.1 - 2.5e-12 46.6 0.1 4.5e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 CEP19840.1 - 1.7e-07 30.2 0.0 2.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DivIC PF04977.10 CEP19842.1 - 0.089 12.2 1.2 0.19 11.2 0.9 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF3488 PF11992.3 CEP19845.1 - 2.1 6.8 4.3 3.2 6.2 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) VIT_2 PF13757.1 CEP19846.1 - 0.12 11.8 0.5 0.32 10.4 0.3 1.7 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain MCLC PF05934.6 CEP19849.1 - 0.26 9.5 3.4 0.065 11.5 0.3 1.5 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) zf-rbx1 PF12678.2 CEP19850.1 - 9.6e-14 51.2 1.3 9.6e-14 51.2 0.9 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CEP19850.1 - 5.6e-12 45.2 3.0 5.6e-12 45.2 2.1 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CEP19850.1 - 4.2e-08 32.7 2.9 1.4e-07 30.9 2.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEP19850.1 - 2.8e-07 30.0 4.9 1.2e-05 24.8 1.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP19850.1 - 1.6e-06 28.0 6.1 2e-06 27.7 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEP19850.1 - 5.1e-06 26.1 1.5 2.4e-05 23.9 1.1 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CEP19850.1 - 1.1e-05 25.0 4.7 7.5e-05 22.3 3.5 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CEP19850.1 - 0.00011 21.9 5.4 0.00076 19.2 3.8 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Suf PF05843.9 CEP19850.1 - 0.00033 20.5 6.2 0.00033 20.5 4.3 2.3 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) zf-C3HC4_4 PF15227.1 CEP19850.1 - 0.00036 20.3 1.8 0.0014 18.4 1.3 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 CEP19850.1 - 0.0023 17.1 4.6 0.0023 17.1 3.2 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger Plasmodium_Vir PF05795.6 CEP19850.1 - 0.0089 15.2 2.7 0.021 14.0 1.8 1.5 1 0 0 1 1 1 1 Plasmodium vivax Vir protein zf-RING_4 PF14570.1 CEP19850.1 - 0.42 10.2 4.4 0.4 10.2 1.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CEP19850.1 - 1.8 8.5 7.9 0.64 10.0 2.8 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain Tim54 PF11711.3 CEP19850.1 - 4.9 5.6 13.4 0.039 12.5 3.0 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 3HCDH_N PF02737.13 CEP19851.1 - 2.8e-60 203.0 4.3 3.7e-60 202.6 2.9 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CEP19851.1 - 7.5e-34 116.0 0.0 2.2e-33 114.5 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 CEP19851.1 - 0.0014 18.3 0.9 0.0021 17.8 0.7 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 CEP19851.1 - 0.057 12.5 0.3 0.092 11.8 0.2 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CEP19851.1 - 0.086 12.6 4.2 0.47 10.2 2.9 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_4 PF02056.11 CEP19851.1 - 0.098 11.9 1.2 0.42 9.9 0.8 2.1 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.9 CEP19851.1 - 0.14 11.4 1.4 0.4 10.0 0.9 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RRM_1 PF00076.17 CEP19852.1 - 1.4e-21 75.9 0.0 1.9e-09 36.9 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 CEP19852.1 - 1.3e-17 62.2 0.3 2.7e-05 23.3 0.0 6.0 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat RRM_6 PF14259.1 CEP19852.1 - 2.5e-15 56.2 0.0 2.2e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP19852.1 - 2.7e-13 49.5 0.2 9.2e-06 25.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 CEP19852.1 - 0.0016 17.9 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_3 PF08777.6 CEP19852.1 - 0.021 14.6 0.0 3.1 7.7 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif Pkinase PF00069.20 CEP19853.1 - 5.3e-71 238.8 0.5 7.9e-71 238.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19853.1 - 2.8e-47 160.9 0.3 1.5e-46 158.6 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19853.1 - 6.5e-08 31.8 0.0 1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 CEP19853.1 - 1.4e-05 25.3 0.9 4.9e-05 23.6 0.6 2.1 1 1 0 1 1 1 1 P21-Rho-binding domain APH PF01636.18 CEP19853.1 - 0.00062 19.5 0.0 0.056 13.1 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 CEP19853.1 - 0.0044 16.1 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Di19_C PF14571.1 CEP19853.1 - 0.035 14.4 0.2 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal adh_short PF00106.20 CEP19854.1 - 1.5e-12 47.7 0.0 2.8e-08 33.8 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CEP19854.1 - 7.2e-05 22.5 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CEP19854.1 - 0.02 14.3 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CEP19854.1 - 0.11 11.4 0.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein CPSF73-100_C PF11718.3 CEP19855.1 - 0.028 13.7 1.8 0.028 13.7 1.2 1.6 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term MIF4G PF02854.14 CEP19856.1 - 1.5e-28 99.6 3.6 1.5e-28 99.6 2.5 2.4 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CEP19856.1 - 2.6e-12 46.4 0.3 1.5e-10 40.7 0.1 3.2 2 1 0 2 2 2 1 MA3 domain CBM_5_12 PF02839.9 CEP19857.1 - 1.2e-14 53.5 33.0 4.6e-08 32.5 5.7 4.7 4 0 0 4 4 4 3 Carbohydrate binding domain Mucin PF01456.12 CEP19857.1 - 1.4 8.6 20.6 2.8 7.6 14.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Trehalose_PPase PF02358.11 CEP19858.1 - 5.1e-59 199.0 0.0 6.2e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CEP19858.1 - 0.039 13.5 0.4 0.3 10.6 0.6 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 CEP19859.1 - 2.6e-49 167.8 41.4 2.6e-49 167.8 28.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP19859.1 - 7.6e-16 57.7 13.4 7.6e-16 57.7 9.3 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CEP19859.1 - 5.2e-12 44.7 20.9 1.9e-11 42.9 14.5 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Viral_Beta_CD PF04530.7 CEP19859.1 - 0.17 12.0 3.8 0.36 10.9 0.1 3.1 3 1 1 4 4 4 0 Viral Beta C/D like family FA_desaturase PF00487.19 CEP19859.1 - 1.6 8.1 10.5 1.2 8.5 5.1 2.4 2 1 0 2 2 2 0 Fatty acid desaturase GCN5L1 PF06320.8 CEP19860.1 - 2.5e-37 127.4 6.8 2.9e-37 127.1 4.7 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Atg14 PF10186.4 CEP19860.1 - 0.003 16.5 5.0 0.0033 16.4 3.5 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 CEP19860.1 - 0.011 14.2 7.5 0.012 14.1 5.2 1.0 1 0 0 1 1 1 0 AAA domain DUF2937 PF11157.3 CEP19860.1 - 0.019 14.3 1.1 0.025 13.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) ISG65-75 PF11727.3 CEP19860.1 - 0.037 13.0 2.6 0.23 10.4 1.8 1.9 1 1 0 1 1 1 0 Invariant surface glycoprotein Peptidase_M17 PF00883.16 CEP19860.1 - 0.052 12.4 0.3 0.055 12.3 0.2 1.1 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain DUF3802 PF12290.3 CEP19860.1 - 0.08 13.2 0.5 0.19 12.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3802) Rsd_AlgQ PF04353.8 CEP19860.1 - 0.089 12.5 3.1 0.11 12.1 2.1 1.1 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ NusB PF01029.13 CEP19860.1 - 0.093 12.7 2.4 0.13 12.2 1.7 1.2 1 0 0 1 1 1 0 NusB family DUF1319 PF07028.6 CEP19860.1 - 0.15 12.2 4.6 0.18 11.9 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Tweety PF04906.8 CEP19860.1 - 0.15 10.4 3.8 0.16 10.3 2.6 1.1 1 0 0 1 1 1 0 Tweety Spectrin PF00435.16 CEP19860.1 - 0.16 12.2 10.5 0.11 12.8 4.6 2.0 1 1 1 2 2 2 0 Spectrin repeat YtzH PF14165.1 CEP19860.1 - 0.3 11.3 5.6 0.57 10.4 3.9 1.5 1 0 0 1 1 1 0 YtzH-like protein DUF3348 PF11828.3 CEP19860.1 - 0.38 10.1 3.4 0.75 9.1 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3348) DUF3510 PF12022.3 CEP19860.1 - 0.75 9.9 5.7 4 7.5 3.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Synaptobrevin PF00957.16 CEP19860.1 - 1 9.0 5.7 0.35 10.4 1.0 2.1 1 1 0 2 2 2 0 Synaptobrevin UPF0118 PF01594.11 CEP19860.1 - 2 7.3 5.3 5.9 5.7 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF20 Snapin_Pallidin PF14712.1 CEP19860.1 - 2.4 8.5 10.7 1.7 8.9 1.7 2.3 1 1 1 2 2 2 0 Snapin/Pallidin YtxH PF12732.2 CEP19860.1 - 5.5 7.4 5.9 79 3.7 4.1 2.1 1 1 0 1 1 1 0 YtxH-like protein P4Ha_N PF08336.6 CEP19860.1 - 6 6.6 9.2 5.4 6.8 0.7 2.1 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region LAG1-DNAbind PF09271.6 CEP19861.1 - 8.5e-31 107.3 15.6 1.9e-17 64.0 0.1 3.5 3 1 1 4 4 4 2 LAG1, DNA binding BTD PF09270.5 CEP19861.1 - 4.7e-22 78.4 1.8 9.2e-13 48.2 0.0 3.6 3 0 0 3 3 3 3 Beta-trefoil DNA-binding domain TIG PF01833.19 CEP19861.1 - 1.3e-05 25.1 0.1 5.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain HlyU PF10115.4 CEP19862.1 - 0.032 14.0 2.2 0.067 13.0 0.1 2.5 3 0 0 3 3 3 0 Transcriptional activator HlyU DUF2076 PF09849.4 CEP19862.1 - 1.5 8.8 27.1 25 4.7 9.9 3.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) HSP70 PF00012.15 CEP19863.1 - 1.9e-264 878.1 12.1 2.2e-264 877.9 8.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEP19863.1 - 4.1e-15 55.2 2.7 2.4e-12 46.1 0.3 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CEP19863.1 - 0.00092 18.8 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CEP19863.1 - 0.017 14.9 9.3 2.6 7.8 0.0 4.8 3 2 0 3 3 3 0 Cell division protein FtsA Ribosomal_L12 PF00542.14 CEP19863.1 - 0.038 13.9 2.4 0.14 12.1 1.7 2.0 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Hydantoinase_A PF01968.13 CEP19863.1 - 0.076 12.1 0.1 0.076 12.1 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase rve PF00665.21 CEP19866.1 - 8.4e-06 25.8 0.0 0.00013 22.0 0.0 2.3 1 1 1 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 CEP19866.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4488 PF14869.1 CEP19868.1 - 0.017 14.7 0.1 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) DDE_Tnp_4 PF13359.1 CEP19869.1 - 3.8e-10 39.5 0.1 0.0001 21.9 0.1 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease Ribosomal_L14e PF01929.12 CEP19869.1 - 0.26 11.6 2.7 0.43 10.9 1.9 1.3 1 0 0 1 1 1 0 Ribosomal protein L14 Daxx PF03344.10 CEP19871.1 - 0.17 10.3 0.2 0.2 10.1 0.2 1.1 1 0 0 1 1 1 0 Daxx Family Peptidase_M13_N PF05649.8 CEP19874.1 - 1.2e-98 330.7 0.0 1.7e-98 330.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CEP19874.1 - 1.1e-66 224.0 0.0 1.6e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 HLH PF00010.21 CEP19875.1 - 5.9e-11 41.8 0.8 1.8e-10 40.3 0.6 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L50 PF10501.4 CEP19877.1 - 3.6e-12 46.2 1.6 5e-12 45.7 0.8 1.3 1 1 0 1 1 1 1 Ribosomal subunit 39S WD40 PF00400.27 CEP19878.1 - 6.4e-55 181.1 13.6 1.2e-07 31.2 0.1 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat Nbas_N PF15492.1 CEP19878.1 - 0.00058 19.0 0.9 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal PH PF00169.24 CEP19878.1 - 0.00099 19.2 1.7 0.00099 19.2 1.2 2.0 2 0 0 2 2 2 1 PH domain Cytochrom_D1 PF02239.11 CEP19878.1 - 0.0021 16.4 0.1 0.0069 14.7 0.1 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain BBS2_Mid PF14783.1 CEP19878.1 - 0.06 13.1 0.3 0.38 10.5 0.1 2.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 CEP19879.1 - 2.4e-53 180.9 0.0 3.5e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19879.1 - 5.3e-25 87.9 0.0 9.6e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19879.1 - 0.0003 19.8 0.0 0.00092 18.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 CEP19879.1 - 0.0031 16.3 0.5 0.0045 15.8 0.3 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Hist_deacetyl PF00850.14 CEP19880.1 - 5.8e-79 265.5 0.0 1.3e-78 264.4 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Far-17a_AIG1 PF04750.9 CEP19880.1 - 4.8e-21 74.8 8.3 7.6e-21 74.1 5.7 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein CAML PF14963.1 CEP19880.1 - 0.39 10.0 1.6 0.67 9.2 1.1 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Aldedh PF00171.17 CEP19881.1 - 1.7e-88 297.0 0.0 2e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HAT PF02184.11 CEP19882.1 - 8.3e-22 76.6 66.4 3.7e-15 55.3 2.3 13.7 15 1 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 CEP19882.1 - 1.3e-17 62.6 12.5 0.012 16.1 0.1 10.0 7 3 5 12 12 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 CEP19882.1 - 3.6e-16 59.2 0.0 0.026 14.8 0.0 7.4 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 CEP19882.1 - 2.8e-14 53.3 4.7 0.25 12.0 0.0 7.9 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 CEP19882.1 - 6.1e-08 32.1 4.3 0.087 12.4 0.0 6.3 5 3 0 5 5 5 2 TPR repeat TPR_17 PF13431.1 CEP19882.1 - 1.9e-07 30.7 0.4 0.031 14.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 CEP19882.1 - 2.2e-06 26.9 13.1 0.087 11.8 0.2 4.4 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CEP19882.1 - 6.8e-05 22.4 6.4 12 6.0 0.0 8.1 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP19882.1 - 0.028 14.3 11.8 1.1 9.1 0.0 6.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEP19882.1 - 0.045 14.2 11.8 1.3 9.6 0.0 7.3 8 1 0 8 8 7 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CEP19882.1 - 3 7.6 35.7 0.089 12.5 1.0 8.3 6 3 3 9 9 9 0 U3 small nucleolar RNA-associated protein 6 Ribosomal_S14 PF00253.16 CEP19883.1 - 1.4e-21 75.5 0.2 4.1e-20 70.9 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e Nucleoplasmin PF03066.10 CEP19884.1 - 4.2 6.8 15.6 0.26 10.8 4.9 2.4 2 0 0 2 2 2 0 Nucleoplasmin peroxidase PF00141.18 CEP19885.1 - 1e-43 149.4 0.0 1.5e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MotB_plug PF13677.1 CEP19885.1 - 0.081 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Rhomboid PF01694.17 CEP19886.1 - 0.042 13.8 0.1 0.06 13.3 0.1 1.1 1 0 0 1 1 1 0 Rhomboid family ATP_transf PF09830.4 CEP19887.1 - 3.1e-22 78.1 0.0 5.5e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 CEP19887.1 - 4.9e-05 23.7 0.1 0.00015 22.1 0.0 1.9 2 0 0 2 2 2 1 HIT domain HTH_Tnp_Tc3_2 PF01498.13 CEP19889.1 - 1.3e-08 34.7 0.0 8.9e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 CEP19889.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_29 PF13551.1 CEP19889.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix KH_1 PF00013.24 CEP19891.1 - 5e-17 61.2 6.6 3e-05 23.5 0.0 6.3 8 0 0 8 8 8 4 KH domain KH_3 PF13014.1 CEP19891.1 - 2.1e-15 55.9 1.4 3.2e-05 23.4 0.0 5.4 6 0 0 6 6 6 3 KH domain VIT1 PF01988.14 CEP19893.1 - 2.1 7.7 7.1 2.5 7.5 4.9 1.0 1 0 0 1 1 1 0 VIT family DUF2183 PF09949.4 CEP19894.1 - 3.9e-31 106.9 2.5 4.6e-31 106.7 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2183) DUF4201 PF13870.1 CEP19894.1 - 2.2e-05 23.9 17.6 2.2e-05 23.9 12.2 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) IncA PF04156.9 CEP19894.1 - 9.3e-05 22.1 19.1 9.3e-05 22.1 13.2 2.3 1 1 1 2 2 2 1 IncA protein LNS2 PF08235.8 CEP19894.1 - 0.0021 17.6 0.0 0.0048 16.4 0.0 1.6 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Reo_sigmaC PF04582.7 CEP19894.1 - 0.03 13.5 7.8 0.051 12.7 4.7 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 CEP19894.1 - 6.4 6.6 40.5 0.083 12.7 10.7 2.5 1 1 1 2 2 2 0 Tropomyosin like Pkinase PF00069.20 CEP19895.1 - 1.2e-74 250.7 0.0 2.5e-74 249.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19895.1 - 1.4e-40 139.0 0.0 2.8e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEP19895.1 - 3.5e-05 23.6 0.0 0.0012 18.6 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEP19895.1 - 0.0079 15.1 0.0 0.023 13.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CEP19895.1 - 0.024 13.6 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CEP19895.1 - 0.04 13.4 0.0 0.04 13.4 0.0 2.5 2 1 1 3 3 3 0 Choline/ethanolamine kinase KorB PF08535.5 CEP19897.1 - 0.0061 16.6 0.1 0.039 14.1 0.0 2.2 2 0 0 2 2 2 1 KorB domain Lamprin PF06403.6 CEP19897.1 - 0.022 14.4 0.5 0.049 13.3 0.1 1.7 2 0 0 2 2 2 0 Lamprin Kinesin PF00225.18 CEP19898.1 - 2.1e-107 358.6 0.5 2.1e-107 358.6 0.4 2.4 2 1 1 3 3 3 1 Kinesin motor domain DUF3584 PF12128.3 CEP19898.1 - 0.066 10.5 69.9 0.014 12.7 29.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Dymeclin PF09742.4 CEP19899.1 - 4.2e-98 329.2 27.8 7.8e-96 321.7 14.9 2.1 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 CEP19899.1 - 0.00029 18.6 17.8 0.00029 18.6 12.3 2.5 2 1 0 2 2 2 1 High-temperature-induced dauer-formation protein Aminotran_1_2 PF00155.16 CEP19900.1 - 3.6e-83 279.5 0.0 4.2e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NIF PF03031.13 CEP19902.1 - 5.2e-31 107.4 0.4 1.1e-30 106.4 0.3 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 CEP19902.1 - 8.9e-11 41.4 0.2 2.4e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CEP19902.1 - 0.00011 22.2 0.1 0.0004 20.4 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain E1-E2_ATPase PF00122.15 CEP19903.1 - 2.1e-59 200.3 4.0 2.1e-59 200.3 2.8 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEP19903.1 - 2.9e-43 147.4 15.3 7.6e-43 146.1 7.1 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEP19903.1 - 7.4e-25 88.6 0.2 2e-24 87.2 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEP19903.1 - 2.9e-19 68.8 0.1 8.2e-19 67.3 0.1 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEP19903.1 - 1e-14 55.1 0.1 3.5e-14 53.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEP19903.1 - 5.4e-12 44.9 0.0 1.4e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEP19903.1 - 0.0015 18.2 0.3 0.0015 18.2 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase B12D PF06522.6 CEP19904.1 - 1.2e-18 66.5 0.0 1.5e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit NPBW PF15180.1 CEP19904.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Neuropeptides B and W MFS_1 PF07690.11 CEP19906.1 - 2.7e-25 88.8 14.2 6.1e-21 74.5 0.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP19906.1 - 1.2e-14 53.7 0.0 2.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CEP19906.1 - 4.2e-05 22.1 6.3 0.0001 20.8 0.3 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 CEP19906.1 - 0.00076 17.8 0.1 0.0013 17.0 0.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2838 PF10998.3 CEP19906.1 - 0.14 12.0 0.6 0.34 10.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Recep_L_domain PF01030.19 CEP19907.1 - 2.1e-11 43.7 3.2 9.3e-05 22.3 0.0 4.2 2 1 1 3 3 3 3 Receptor L domain DDE_3 PF13358.1 CEP19910.1 - 9.9e-30 103.2 0.0 1.7e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 CEP19910.1 - 0.00027 20.8 0.4 0.00081 19.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 CEP19910.1 - 0.0003 21.5 0.0 0.00084 20.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 CEP19910.1 - 0.001 18.6 0.1 0.0033 17.0 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain DDE_1 PF03184.14 CEP19910.1 - 0.0019 17.4 0.1 0.018 14.2 0.1 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 CEP19910.1 - 0.0021 17.5 0.0 0.0056 16.2 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1804 PF08822.6 CEP19910.1 - 0.003 17.3 0.1 0.023 14.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1804) HTH_29 PF13551.1 CEP19910.1 - 0.0043 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 CEP19910.1 - 0.0097 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_7 PF02796.10 CEP19910.1 - 0.08 12.8 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase rve PF00665.21 CEP19913.1 - 8.5e-09 35.5 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEP19913.1 - 0.00032 20.2 0.0 0.0008 19.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Kinesin PF00225.18 CEP19914.1 - 3e-76 256.2 0.7 4e-76 255.8 0.5 1.1 1 0 0 1 1 1 1 Kinesin motor domain F-box-like PF12937.2 CEP19915.1 - 2.2e-06 27.3 0.5 2e-05 24.2 0.1 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CEP19915.1 - 5 6.8 9.4 5.8 6.6 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) KOW PF00467.24 CEP19917.1 - 8.3e-07 28.4 1.0 1.5e-06 27.7 0.7 1.4 1 0 0 1 1 1 1 KOW motif LRR_4 PF12799.2 CEP19918.1 - 3.6e-27 93.4 29.4 9.4e-09 34.7 0.8 5.0 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP19918.1 - 4.1e-25 87.3 19.9 3.3e-08 33.1 5.4 4.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CEP19918.1 - 2.5e-16 57.1 27.1 0.04 13.9 0.6 9.3 10 0 0 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 CEP19918.1 - 4.7e-11 41.0 21.0 0.18 12.1 0.7 8.6 8 0 0 8 8 8 4 Leucine rich repeat LRR_6 PF13516.1 CEP19918.1 - 2.3e-06 27.0 21.8 0.39 10.9 0.5 8.2 7 1 1 8 8 8 2 Leucine Rich repeat LRR_9 PF14580.1 CEP19918.1 - 0.035 13.6 5.9 0.15 11.5 0.1 2.8 1 1 3 4 4 4 0 Leucine-rich repeat DDE_3 PF13358.1 CEP19919.1 - 9.7e-27 93.5 0.0 1.8e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEP19919.1 - 0.057 13.5 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain DDE_3 PF13358.1 CEP19920.1 - 3e-17 62.7 0.0 4.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CEP19920.1 - 0.0085 16.8 0.3 0.025 15.3 0.0 2.0 3 0 0 3 3 3 1 Homeodomain-like domain ADH_N_assoc PF13823.1 CEP19920.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TPP_enzyme_C PF02775.16 CEP19922.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain WSS_VP PF12175.3 CEP19922.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Hist_deacetyl PF00850.14 CEP19924.1 - 1.8e-50 172.0 0.1 2.1e-46 158.6 0.0 2.7 1 1 1 2 2 2 2 Histone deacetylase domain Tudor-knot PF11717.3 CEP19924.1 - 0.031 13.9 0.1 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain ABC2_membrane PF01061.19 CEP19925.1 - 1.4e-37 128.8 24.5 1.4e-37 128.8 17.0 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CEP19925.1 - 2.7e-29 102.2 0.8 3.9e-29 101.7 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CEP19925.1 - 1.4e-09 38.3 0.0 9.3e-08 32.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 CEP19925.1 - 2.9e-07 29.8 27.6 4.2e-06 26.0 18.9 2.3 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 CEP19925.1 - 1.1e-05 24.9 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEP19925.1 - 0.00027 21.7 0.0 0.0008 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CEP19925.1 - 0.00098 18.6 0.1 0.0021 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain hEGF PF12661.2 CEP19925.1 - 0.001 19.0 24.8 0.039 14.0 2.3 4.3 3 0 0 3 3 3 2 Human growth factor-like EGF DUF258 PF03193.11 CEP19925.1 - 0.0011 18.2 0.1 0.0031 16.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CEP19925.1 - 0.0012 18.8 1.1 0.0041 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 CEP19925.1 - 0.0014 17.9 0.0 0.24 10.5 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 CEP19925.1 - 0.002 18.4 0.4 0.0067 16.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEP19925.1 - 0.0028 17.8 0.3 0.013 15.6 0.0 2.4 3 0 0 3 3 1 1 AAA domain AAA PF00004.24 CEP19925.1 - 0.0032 17.6 0.1 0.12 12.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CEP19925.1 - 0.0072 15.0 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 CEP19925.1 - 0.009 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 CEP19925.1 - 0.016 14.9 0.1 0.086 12.6 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 CEP19925.1 - 0.017 15.0 0.2 0.046 13.6 0.2 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEP19925.1 - 0.019 14.5 0.1 0.044 13.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.20 CEP19925.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 CEP19925.1 - 0.021 14.7 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CEP19925.1 - 0.034 13.8 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CEP19925.1 - 0.042 14.1 0.7 0.07 13.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 CEP19925.1 - 0.043 13.6 0.3 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 CEP19925.1 - 0.078 12.0 0.0 0.54 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF3752 PF12572.3 CEP19925.1 - 0.087 12.9 2.2 0.14 12.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) RecA PF00154.16 CEP19925.1 - 0.14 11.1 0.1 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein cobW PF02492.14 CEP19925.1 - 0.16 11.4 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 CEP19925.1 - 0.27 10.7 0.1 0.51 9.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CEP19925.1 - 1.1 8.7 5.2 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain zf-met PF12874.2 CEP19926.1 - 1.6e-13 50.3 99.2 0.0098 16.0 0.3 12.2 12 0 0 12 12 12 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEP19926.1 - 7.9e-08 32.2 103.5 0.0056 16.7 1.4 11.9 12 0 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CEP19926.1 - 0.00086 19.5 11.1 0.0022 18.2 1.9 13.2 13 0 0 13 13 13 4 Zinc finger, C2H2 type Rad50_zn_hook PF04423.9 CEP19926.1 - 0.0057 16.0 0.9 1.3 8.5 0.2 3.2 2 0 0 2 2 2 2 Rad50 zinc hook motif DUF4251 PF14059.1 CEP19926.1 - 0.12 12.2 4.6 0.046 13.5 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) Ribosomal_L18e PF00828.14 CEP19927.1 - 2.5e-24 86.0 0.4 2.5e-24 86.0 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 IATP PF04568.7 CEP19928.1 - 1.2e-05 25.2 0.9 1.4e-05 24.9 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF572 PF04502.8 CEP19928.1 - 0.00014 21.2 1.4 0.00016 20.9 0.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) NYD-SP28 PF14772.1 CEP19928.1 - 0.048 13.7 2.4 0.068 13.2 1.5 1.5 1 1 0 1 1 1 0 Sperm tail Blo-t-5 PF11642.3 CEP19928.1 - 0.06 13.1 0.9 0.08 12.7 0.6 1.2 1 0 0 1 1 1 0 Mite allergen Blo t 5 DUF802 PF05650.6 CEP19928.1 - 0.11 12.5 2.4 2.1 8.5 1.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF802) YABBY PF04690.8 CEP19928.1 - 0.15 12.3 0.7 0.17 12.0 0.5 1.1 1 0 0 1 1 1 0 YABBY protein PRELI PF04707.9 CEP19929.1 - 0.028 13.9 1.4 0.042 13.4 0.2 1.8 2 0 0 2 2 2 0 PRELI-like family Amdo_NSP PF12475.3 CEP19929.1 - 0.48 10.3 3.2 1.7 8.6 0.2 2.3 2 0 0 2 2 2 0 Amdovirus non-structural protein RVT_1 PF00078.22 CEP19930.1 - 2.8e-38 131.4 1.3 7.3e-38 130.0 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP19930.1 - 6.7e-11 42.5 0.6 1.4e-10 41.5 0.4 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CEP19930.1 - 4.9e-07 29.9 0.3 2.2e-06 27.8 0.2 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 CEP19930.1 - 0.2 11.6 13.5 0.016 15.0 1.2 2.7 2 0 0 2 2 2 0 Zinc knuckle MtrF PF09472.5 CEP19930.1 - 0.32 10.2 0.0 0.73 9.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) HNH PF01844.18 CEP19930.1 - 0.38 10.6 6.3 1.2 9.0 0.0 3.5 3 0 0 3 3 3 0 HNH endonuclease zf-CCHC_3 PF13917.1 CEP19930.1 - 8 6.2 15.5 0.056 13.1 2.1 2.9 1 1 1 2 2 2 0 Zinc knuckle JAB PF01398.16 CEP19931.1 - 5.4e-15 55.1 0.0 1.6e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-H2C2_2 PF13465.1 CEP19932.1 - 2.9e-16 58.8 27.0 1.7e-06 28.0 0.3 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CEP19932.1 - 7.3e-15 54.3 24.8 0.00013 22.0 1.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP19932.1 - 2.3e-05 24.4 9.6 0.0011 19.1 0.6 5.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP19932.1 - 0.0024 17.9 5.4 6.3 7.0 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEP19932.1 - 0.011 15.8 4.7 7.1 6.9 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BAF1_ABF1 PF04684.8 CEP19932.1 - 1.4 7.6 8.4 1.7 7.3 5.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3591 PF12157.3 CEP19933.1 - 1.8e-170 567.2 0.0 1.8e-170 567.2 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CEP19933.1 - 5.8e-06 25.8 0.7 1.4e-05 24.6 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CEP19933.1 - 0.88 9.6 3.5 1.9 8.5 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF912 PF06024.7 CEP19933.1 - 7.8 6.6 6.6 2.2 8.3 1.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Bin3 PF06859.7 CEP19934.1 - 2.4e-35 120.8 0.1 7.9e-35 119.1 0.0 1.9 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 CEP19934.1 - 1.2e-14 54.8 0.0 2.5e-14 53.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEP19934.1 - 5.2e-13 49.0 0.0 7.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEP19934.1 - 7.7e-12 45.0 0.5 7.4e-07 28.8 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CEP19934.1 - 1.4e-09 38.3 0.0 0.00046 20.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 CEP19934.1 - 4.1e-07 29.5 0.1 5.5e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CEP19934.1 - 8.2e-06 26.2 0.0 0.057 13.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.8 CEP19934.1 - 1.4e-05 24.3 0.5 3.2e-05 23.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CEP19934.1 - 1.5e-05 25.0 0.0 4.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEP19934.1 - 3.4e-05 24.1 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEP19934.1 - 0.001 18.1 0.0 0.0031 16.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 CEP19934.1 - 0.0012 17.9 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.7 CEP19934.1 - 0.0083 15.4 0.0 0.04 13.2 0.0 1.9 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase MetW PF07021.7 CEP19934.1 - 0.023 14.0 0.0 0.062 12.6 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PCMT PF01135.14 CEP19934.1 - 0.072 12.6 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 CEP19934.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase FmrO PF07091.6 CEP19934.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 CEP19934.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain rRNA_proc-arch PF13234.1 CEP19936.1 - 1.9e-86 289.5 0.2 3.3e-86 288.7 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CEP19936.1 - 1.2e-62 210.3 1.1 2.9e-62 209.0 0.8 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CEP19936.1 - 4.8e-22 78.2 0.1 2e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEP19936.1 - 1.5e-08 34.3 0.0 3.8e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEP19936.1 - 0.0019 18.0 0.5 0.069 12.9 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3450 PF11932.3 CEP19936.1 - 0.0046 16.2 0.6 2 7.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) T2SE PF00437.15 CEP19936.1 - 0.0064 15.4 0.0 0.018 13.9 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein PMT_C PF11647.3 CEP19936.1 - 0.063 12.8 0.2 0.22 11.1 0.1 2.0 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 MutS_V PF00488.16 CEP19937.1 - 2.4e-29 102.4 0.1 3e-29 102.1 0.1 1.0 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CEP19938.1 - 2.1e-23 83.1 1.3 2.9e-23 82.7 0.9 1.2 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 CEP19938.1 - 3.7e-07 30.2 1.9 9.5e-07 28.9 1.4 1.7 1 0 0 1 1 1 1 MutS family domain IV WD40 PF00400.27 CEP19939.1 - 1.2e-37 126.4 0.8 1.5e-12 46.8 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat bZIP_1 PF00170.16 CEP19939.1 - 9.9e-05 22.2 1.1 0.00017 21.4 0.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor eIF2A PF08662.6 CEP19939.1 - 0.00016 21.4 0.0 0.58 9.8 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DivIC PF04977.10 CEP19939.1 - 0.017 14.5 0.7 0.032 13.7 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 CEP19939.1 - 0.02 15.2 0.0 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Nup160 PF11715.3 CEP19939.1 - 0.026 12.6 0.0 3.3 5.7 0.0 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 FlxA PF14282.1 CEP19939.1 - 0.18 11.7 1.4 0.35 10.8 0.9 1.3 1 0 0 1 1 1 0 FlxA-like protein Trehalase PF01204.13 CEP19940.1 - 7.7e-176 585.6 2.5 9.7e-176 585.3 1.7 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CEP19940.1 - 5.5e-13 47.9 0.1 1.1e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain CobT PF06213.7 CEP19941.1 - 0.045 12.8 6.6 0.076 12.1 4.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 CEP19941.1 - 0.26 9.1 10.1 0.33 8.8 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CEP19941.1 - 1 7.2 9.3 1.8 6.5 6.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 CEP19941.1 - 6.7 5.5 14.0 2.7 6.8 4.9 2.9 4 0 0 4 4 4 0 Nop53 (60S ribosomal biogenesis) MFS_1 PF07690.11 CEP19942.1 - 1.4e-31 109.5 21.8 5.3e-31 107.6 14.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 CEP19942.1 - 0.014 14.5 3.7 0.023 13.8 1.6 1.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1616) DUF2306 PF10067.4 CEP19942.1 - 0.82 9.8 5.3 6 7.0 0.2 3.7 3 1 0 3 3 3 0 Predicted membrane protein (DUF2306) DUF3816 PF12822.2 CEP19942.1 - 6.1 6.6 19.9 0.37 10.6 4.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3816) Rad51 PF08423.6 CEP19943.1 - 1.9e-26 92.5 0.0 3e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CEP19943.1 - 4.7e-07 29.4 0.0 1.2e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.10 CEP19943.1 - 9.2e-05 21.4 0.3 0.00015 20.7 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Med2 PF11214.3 CEP19943.1 - 0.037 14.0 2.1 0.049 13.6 0.3 1.9 2 0 0 2 2 2 0 Mediator complex subunit 2 DUF1118 PF06549.7 CEP19943.1 - 0.066 13.3 0.2 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) KaiC PF06745.8 CEP19943.1 - 0.38 9.8 2.1 0.45 9.5 0.0 2.0 2 1 1 3 3 3 0 KaiC Utp12 PF04003.7 CEP19944.1 - 3.8e-13 49.3 1.0 5.7e-13 48.7 0.7 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Astro_capsid PF03115.9 CEP19944.1 - 5.9 5.0 6.0 6.1 4.9 4.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Mg_trans_NIPA PF05653.9 CEP19945.1 - 2.8e-34 118.4 6.8 3.4e-34 118.1 4.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA Glyco_transf_11 PF01531.11 CEP19945.1 - 0.042 12.8 0.1 0.062 12.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 7TMR-DISM_7TM PF07695.6 CEP19945.1 - 0.058 13.0 5.7 0.071 12.7 3.9 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling TrbC PF04956.8 CEP19945.1 - 0.26 11.2 2.9 0.42 10.6 1.9 1.4 1 1 0 1 1 1 0 TrbC/VIRB2 family YoqO PF14037.1 CEP19945.1 - 0.29 11.2 4.0 0.53 10.4 2.8 1.4 1 1 0 1 1 1 0 YoqO-like protein EamA PF00892.15 CEP19945.1 - 3.5 7.6 9.2 7.9 6.5 6.4 1.6 1 1 0 1 1 1 0 EamA-like transporter family rve PF00665.21 CEP19947.1 - 3.9e-18 65.6 0.0 2.2e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CEP19947.1 - 6.4e-10 38.5 2.2 1.1e-08 34.6 1.2 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CEP19947.1 - 0.0014 17.9 0.2 0.0049 16.2 0.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger TraG_N PF07916.6 CEP19947.1 - 0.0073 14.8 0.0 0.013 13.9 0.0 1.3 1 0 0 1 1 1 1 TraG-like protein, N-terminal region UBN2 PF14223.1 CEP19947.1 - 0.011 15.5 0.0 0.062 13.1 0.0 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Asp_protease_2 PF13650.1 CEP19947.1 - 0.03 14.8 0.0 0.087 13.3 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Eapp_C PF10238.4 CEP19948.1 - 0.25 11.2 3.0 0.46 10.3 2.1 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein SdrG_C_C PF10425.4 CEP19949.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin PIF1 PF05970.9 CEP19950.1 - 4.8e-16 58.6 0.0 9.3e-15 54.4 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 CEP19950.1 - 1.3e-11 44.5 0.0 1.5e-10 41.1 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEP19950.1 - 1.6e-05 22.8 0.0 2.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 CEP19950.1 - 2.6e-05 23.8 0.1 8.5e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Transposase_21 PF02992.9 CEP19953.1 - 0.001 18.1 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 CCP_MauG PF03150.9 CEP19954.1 - 0.033 14.4 0.0 0.036 14.3 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase DUF2151 PF10221.4 CEP19956.1 - 1.6e-05 23.3 0.9 0.00063 18.0 0.6 2.1 1 1 0 1 1 1 1 Cell cycle and development regulator RFPL3_antisense PF10489.4 CEP19956.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense FGE-sulfatase PF03781.11 CEP19957.1 - 1e-37 129.8 3.4 1.7e-37 129.1 2.4 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Kinesin PF00225.18 CEP19958.1 - 6.4e-113 376.8 1.3 6.4e-113 376.8 0.9 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 CEP19958.1 - 1.5e-33 115.4 0.1 6.9e-33 113.2 0.0 2.3 2 0 0 2 2 2 1 Kinesin protein PH PF00169.24 CEP19958.1 - 1.2e-14 54.3 0.4 4.4e-14 52.5 0.3 2.0 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 CEP19958.1 - 1.3e-06 28.2 2.1 1.4e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 Kinesin protein 1B PH_11 PF15413.1 CEP19958.1 - 0.0049 17.1 0.1 0.23 11.7 0.1 3.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 CEP19958.1 - 0.059 13.5 0.2 0.059 13.5 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Sel1 PF08238.7 CEP19960.1 - 2.2e-36 123.4 20.6 1.2e-07 32.1 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat RNA12 PF10443.4 CEP19961.1 - 5.1e-113 377.8 2.6 7.6e-112 373.9 1.8 2.0 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 CEP19961.1 - 9.1e-12 45.1 0.1 2.8e-10 40.2 0.1 2.6 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 CEP19961.1 - 1.5e-05 24.5 0.0 3.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 CEP19961.1 - 2e-05 24.6 0.0 6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RRM_6 PF14259.1 CEP19961.1 - 0.0012 18.8 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEP19961.1 - 0.0024 17.7 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.1 CEP19961.1 - 0.0026 17.9 0.4 0.025 14.7 0.3 2.4 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 CEP19961.1 - 0.0091 16.4 0.2 0.07 13.6 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein DUF2487 PF10673.4 CEP19961.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) AAA_24 PF13479.1 CEP19961.1 - 0.036 13.6 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEP19961.1 - 0.037 13.9 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CEP19961.1 - 0.04 12.8 0.0 0.094 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 CEP19961.1 - 0.076 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CEP19961.1 - 0.14 11.3 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mito_carr PF00153.22 CEP19962.1 - 9.6e-69 227.1 2.5 4e-23 80.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chitin_synth_2 PF03142.10 CEP19963.1 - 5.9e-96 321.9 12.1 2.2e-74 250.7 0.0 2.4 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 CEP19963.1 - 1.1e-05 25.3 0.0 0.0035 17.1 0.0 3.3 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEP19963.1 - 9.2e-05 22.1 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEP19963.1 - 0.00048 19.4 0.0 0.00097 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 CEP19963.1 - 0.009 15.7 0.0 0.026 14.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CCDC66 PF15236.1 CEP19963.1 - 1.3 8.6 7.4 2.5 7.6 5.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Cyclin PF08613.6 CEP19964.1 - 3.3e-15 56.7 2.4 1.3e-14 54.8 1.7 1.9 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEP19964.1 - 0.018 14.5 4.2 0.16 11.5 0.3 3.1 2 1 0 2 2 2 0 Cyclin, N-terminal domain zf-RanBP PF00641.13 CEP19965.1 - 1.2e-09 37.1 2.1 1.7e-09 36.6 1.5 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 CEP19965.1 - 1.7e-08 33.9 0.0 2.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEP19965.1 - 2.4e-05 24.2 0.0 9.9e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) INTS5_C PF14838.1 CEP19966.1 - 3.6e-08 32.1 0.7 0.0008 17.8 0.0 2.5 2 0 0 2 2 2 2 Integrator complex subunit 5 C-terminus INTS5_N PF14837.1 CEP19966.1 - 0.0084 15.5 0.4 0.34 10.2 0.0 2.7 2 0 0 2 2 2 1 Integrator complex subunit 5 N-terminus CRM1_C PF08767.6 CEP19967.1 - 2.3e-06 26.7 7.8 2.8e-06 26.4 0.3 3.3 4 0 0 4 4 4 2 CRM1 C terminal HEAT PF02985.17 CEP19967.1 - 0.011 15.7 0.2 1.7 8.9 0.0 3.7 2 0 0 2 2 2 0 HEAT repeat IBN_N PF03810.14 CEP19967.1 - 0.02 14.7 0.0 0.11 12.4 0.0 2.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain Reprolysin_5 PF13688.1 CEP19968.1 - 3.3e-41 141.3 1.3 3.3e-41 141.3 0.9 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 CEP19968.1 - 6.5e-39 133.6 1.1 1.8e-38 132.1 0.1 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CEP19968.1 - 1.4e-33 116.3 0.2 5.3e-33 114.5 0.1 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CEP19968.1 - 3e-18 66.5 2.4 3.8e-18 66.2 0.0 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CEP19968.1 - 3.4e-08 33.6 8.3 3.4e-08 33.6 5.8 3.9 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 CEP19968.1 - 1.6e-06 27.9 0.0 3.8e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide UDPGT PF00201.13 CEP19969.1 - 1.9e-28 99.2 0.1 3.5e-28 98.4 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CEP19969.1 - 3.7e-08 33.2 0.0 6.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CEP19969.1 - 4.6e-05 22.7 0.0 0.083 12.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 1 TnpW PF14202.1 CEP19969.1 - 0.15 11.6 0.4 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpW zf-HC5HC2H_2 PF13832.1 CEP19970.1 - 5.6e-33 113.2 9.5 5.6e-33 113.2 6.6 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CEP19970.1 - 1.3e-25 89.3 7.8 1.3e-25 89.3 5.4 2.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain Bromodomain PF00439.20 CEP19970.1 - 2.8e-21 75.2 0.8 9.7e-21 73.4 0.3 2.2 2 0 0 2 2 2 1 Bromodomain EPL1 PF10513.4 CEP19970.1 - 2.1e-20 73.5 4.3 2.1e-20 73.5 3.0 4.0 4 1 0 4 4 4 1 Enhancer of polycomb-like PHD_2 PF13831.1 CEP19970.1 - 1.4e-14 53.0 2.8 1.4e-14 53.0 1.9 2.9 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.12 CEP19970.1 - 7.6e-13 48.4 0.3 3.8e-12 46.2 0.2 2.3 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 CEP19970.1 - 1.5e-08 34.1 9.6 1.5e-08 34.1 6.7 2.9 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 CEP19970.1 - 0.0048 16.6 1.2 0.0048 16.6 0.8 2.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DDE_3 PF13358.1 CEP19973.1 - 6.6e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Transformer PF06495.6 CEP19977.1 - 0.011 15.6 5.3 0.019 14.8 3.6 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Corona_nucleoca PF00937.13 CEP19977.1 - 0.27 10.1 5.2 0.4 9.5 3.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SH3_9 PF14604.1 CEP19979.1 - 3.8e-13 48.7 1.1 5.4e-13 48.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CEP19979.1 - 4.6e-13 48.3 0.1 9.2e-13 47.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEP19979.1 - 2.1e-09 36.7 0.0 4.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Bud13 PF09736.4 CEP19979.1 - 1.1 9.5 15.5 1.4 9.1 10.3 1.6 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex YjgP_YjgQ PF03739.9 CEP19979.1 - 3.8 6.1 8.7 4.9 5.7 6.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family adh_short PF00106.20 CEP19980.1 - 2.4e-25 89.3 0.5 3e-25 89.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEP19980.1 - 4.9e-23 82.1 0.0 5.9e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEP19980.1 - 2.7e-09 36.9 0.1 3.8e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CEP19980.1 - 0.0019 17.1 0.1 0.0022 16.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PH PF00169.24 CEP19981.1 - 0.0069 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 PH domain Sad1_UNC PF07738.8 CEP19982.1 - 4e-27 94.6 0.0 1.3e-26 93.0 0.0 1.9 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1673 PF07895.6 CEP19982.1 - 0.0017 17.8 1.5 0.0029 17.1 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) DUF1640 PF07798.6 CEP19982.1 - 0.014 15.4 0.8 0.035 14.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Keratin_assoc PF09775.4 CEP19982.1 - 0.034 13.6 0.1 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 CDP-OH_P_transf PF01066.16 CEP19983.1 - 3.4e-12 46.5 3.9 3.4e-12 46.5 2.7 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3863 PF12979.2 CEP19984.1 - 0.012 14.2 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) SAM_1 PF00536.25 CEP19985.1 - 0.00059 19.9 0.2 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CEP19985.1 - 0.0079 16.0 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) COG5 PF10392.4 CEP19985.1 - 0.019 14.9 5.4 2.7 7.9 0.3 2.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 NmrA PF05368.8 CEP19985.1 - 0.1 11.8 0.1 0.89 8.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family CHCH PF06747.8 CEP19986.1 - 7.1e-08 32.1 3.4 1.3e-07 31.2 2.4 1.5 1 0 0 1 1 1 1 CHCH domain ECIST_Cterm PF14784.1 CEP19986.1 - 0.0063 16.4 0.5 0.0063 16.4 0.4 1.6 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein GCK PF07802.6 CEP19986.1 - 0.49 10.5 4.2 1.2 9.3 2.3 2.0 1 1 1 2 2 2 0 GCK domain SDA1 PF05285.7 CEP19986.1 - 1.2 8.2 7.6 1.6 7.9 5.3 1.2 1 0 0 1 1 1 0 SDA1 Voldacs PF03517.8 CEP19986.1 - 1.9 8.3 8.4 0.66 9.8 3.2 2.2 1 1 1 2 2 2 0 Regulator of volume decrease after cellular swelling Pex14_N PF04695.8 CEP19986.1 - 3.3 7.7 8.1 1.4 8.9 0.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nop14 PF04147.7 CEP19986.1 - 5.6 4.7 7.7 7.1 4.4 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4194 PF13835.1 CEP19987.1 - 0.019 14.4 0.4 0.021 14.2 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) DPCD PF14913.1 CEP19987.1 - 0.032 13.3 1.0 0.034 13.2 0.7 1.0 1 0 0 1 1 1 0 DPCD protein family Med31 PF05669.7 CEP19987.1 - 0.042 13.5 0.4 0.14 11.8 0.2 1.8 1 1 1 2 2 2 0 SOH1 DUF2399 PF09664.5 CEP19987.1 - 0.055 13.3 0.9 0.06 13.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Glyco_hydro_72 PF03198.9 CEP19988.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 2 0 0 2 2 2 0 Glucanosyltransferase Cullin_binding PF03556.10 CEP19988.1 - 0.085 12.9 0.1 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Cullin binding Pkinase PF00069.20 CEP19989.1 - 1.6e-56 191.3 0.0 4.7e-41 140.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEP19989.1 - 3.4e-23 82.0 0.0 2.4e-22 79.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP19989.1 - 5.4e-08 32.1 0.0 1.6e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CEP19989.1 - 2.4e-07 30.0 0.0 3.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEP19989.1 - 0.00025 20.8 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEP19989.1 - 0.0046 16.5 0.1 0.0063 16.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 CEP19989.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1152 PF06626.7 CEP19989.1 - 0.22 10.6 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Ribosomal_L30 PF00327.15 CEP19990.1 - 9.8e-09 34.6 0.1 9.8e-09 34.6 0.1 2.4 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CEP19990.1 - 0.00023 21.1 11.7 0.00023 21.1 8.1 2.1 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain IncFII_repA PF02387.10 CEP19990.1 - 0.003 16.7 7.1 0.0044 16.2 4.9 1.2 1 0 0 1 1 1 1 IncFII RepA protein family Coiled-coil_56 PF09813.4 CEP19990.1 - 0.43 10.5 4.3 0.96 9.4 3.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 CRF PF00473.12 CEP19990.1 - 0.51 10.4 2.5 1.2 9.3 1.8 1.6 1 0 0 1 1 1 0 Corticotropin-releasing factor family PGC7_Stella PF15549.1 CEP19990.1 - 1.8 8.5 4.9 3.5 7.5 3.4 1.4 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Phage_integrase PF00589.17 CEP19991.1 - 6.7e-05 22.6 0.3 0.00018 21.1 0.2 1.7 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.1 CEP19991.1 - 0.0061 16.8 0.1 0.029 14.6 0.1 2.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain RVT_1 PF00078.22 CEP19991.1 - 0.017 14.5 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Arf PF00025.16 CEP19992.1 - 4.8e-78 260.3 0.0 5.2e-78 260.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CEP19992.1 - 3.6e-13 49.1 0.0 4.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CEP19992.1 - 7.2e-13 48.2 0.0 7.9e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CEP19992.1 - 1.2e-12 47.2 1.3 1.9e-09 36.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CEP19992.1 - 2.9e-11 42.9 0.0 3.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEP19992.1 - 4.8e-09 36.7 0.0 7.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEP19992.1 - 4.5e-06 26.6 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CEP19992.1 - 0.005 15.9 0.5 0.012 14.7 0.3 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CEP19992.1 - 0.016 14.6 0.1 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CEP19992.1 - 0.099 12.5 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEP19992.1 - 0.31 10.9 1.3 4.6 7.1 0.9 2.1 1 1 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.14 CEP19993.1 - 2.1e-22 79.7 0.2 4.2e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TPR_19 PF14559.1 CEP19993.1 - 1.7e-07 31.4 1.7 0.12 12.7 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEP19993.1 - 1.2e-06 28.0 8.7 0.086 12.4 0.4 6.2 3 2 2 5 5 5 3 TPR repeat TPR_1 PF00515.23 CEP19993.1 - 5.5e-06 25.7 5.4 0.015 14.8 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEP19993.1 - 6.2e-06 25.6 5.1 1.2 9.0 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEP19993.1 - 7.8e-06 26.4 7.6 0.042 14.5 0.5 6.2 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEP19993.1 - 1.8e-05 24.9 9.3 2 9.2 0.0 6.5 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEP19993.1 - 3.8e-05 23.2 16.4 0.61 10.1 0.2 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat Apc3 PF12895.2 CEP19993.1 - 0.00093 19.2 7.5 0.0015 18.6 0.2 4.2 5 0 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CEP19993.1 - 0.0024 17.9 1.7 0.46 10.8 0.1 4.8 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEP19993.1 - 0.0032 17.8 9.8 5.5 7.6 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 CEP19993.1 - 0.0067 16.3 2.1 0.29 11.0 0.1 3.7 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CEP19993.1 - 0.0091 15.9 9.5 0.025 14.4 0.2 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CEP19993.1 - 0.18 11.6 3.0 3.2 7.6 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEP19993.1 - 0.34 10.8 7.4 9.7 6.2 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Asp_protease_2 PF13650.1 CEP19995.1 - 2.9e-07 30.8 0.0 6.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CEP19995.1 - 9.7e-05 22.2 0.1 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEP19995.1 - 0.0033 17.1 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CEP19995.1 - 0.036 14.0 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Transposase_21 PF02992.9 CEP19998.1 - 0.075 12.1 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Transposase family tnp2 Peptidase_M54 PF07998.6 CEP19999.1 - 0.053 13.2 0.1 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M54 PIF1 PF05970.9 CEP20003.1 - 1.2e-103 346.8 0.0 1.7e-103 346.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CEP20003.1 - 7.9e-08 32.1 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CEP20003.1 - 0.00013 19.8 0.1 0.0004 18.2 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 CEP20003.1 - 0.00016 21.3 0.0 0.00043 19.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 CEP20003.1 - 0.0055 16.8 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CEP20003.1 - 0.036 13.5 0.0 3.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 CEP20003.1 - 0.055 12.0 0.0 0.098 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 CEP20003.1 - 0.091 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 CEP20003.1 - 0.098 12.6 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 CEP20003.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-CCHC PF00098.18 CEP20004.1 - 1.8e-06 27.5 28.0 0.14 12.1 1.0 5.4 5 0 0 5 5 5 4 Zinc knuckle Zn_Tnp_IS1595 PF12760.2 CEP20004.1 - 1.3e-05 24.9 23.1 0.21 11.4 1.2 5.1 4 1 1 5 5 5 3 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 CEP20004.1 - 1.6e-05 24.7 19.3 0.18 11.8 0.2 5.3 5 0 0 5 5 5 3 zinc-finger DUF164 PF02591.10 CEP20004.1 - 5.8e-05 22.8 16.9 1 9.2 0.1 5.4 5 0 0 5 5 5 3 Putative zinc ribbon domain zinc_ribbon_2 PF13240.1 CEP20004.1 - 0.00018 20.8 12.9 3.7 7.1 0.2 5.1 5 0 0 5 5 5 3 zinc-ribbon domain zf-ribbon_3 PF13248.1 CEP20004.1 - 0.0002 20.4 18.7 0.94 8.7 0.1 5.3 5 0 0 5 5 5 3 zinc-ribbon domain DnaJ_CXXCXGXG PF00684.14 CEP20004.1 - 0.00031 20.7 24.7 0.1 12.6 1.2 4.7 3 1 1 4 4 4 2 DnaJ central domain Zn-ribbon_8 PF09723.5 CEP20004.1 - 0.00081 19.2 21.5 1.1 9.2 0.1 5.6 4 2 2 6 6 6 2 Zinc ribbon domain Lar_restr_allev PF14354.1 CEP20004.1 - 0.0013 18.9 22.7 0.036 14.3 2.0 3.9 2 2 0 2 2 2 1 Restriction alleviation protein Lar zf-C4_Topoisom PF01396.14 CEP20004.1 - 0.029 13.8 13.8 9.2 5.8 0.1 5.0 5 0 0 5 5 5 0 Topoisomerase DNA binding C4 zinc finger DZR PF12773.2 CEP20004.1 - 0.051 13.3 23.4 83 3.1 11.2 4.1 1 1 1 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 CEP20004.1 - 0.054 13.2 17.3 1.2 8.9 0.1 5.1 5 0 0 5 5 5 0 PhnA Zinc-Ribbon FYDLN_acid PF09538.5 CEP20004.1 - 0.29 11.7 7.9 2.5 8.7 0.0 4.0 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) Ogr_Delta PF04606.7 CEP20004.1 - 0.58 9.8 31.3 2.3 7.9 0.4 5.8 5 1 1 6 6 6 0 Ogr/Delta-like zinc finger GFA PF04828.9 CEP20004.1 - 0.68 9.9 18.9 0.49 10.3 1.5 4.1 1 1 4 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme zf-Di19 PF05605.7 CEP20004.1 - 0.95 9.6 19.8 5.2 7.2 0.2 5.0 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.7 CEP20004.1 - 1.3 8.8 17.7 5.3 6.9 0.1 4.3 3 1 2 5 5 5 0 zinc-ribbons UPF0547 PF10571.4 CEP20004.1 - 1.3 8.7 26.1 1.5 8.5 0.5 4.7 4 1 1 5 5 5 0 Uncharacterised protein family UPF0547 Cys_rich_KTR PF14205.1 CEP20004.1 - 1.4 8.3 11.6 16 5.0 0.1 4.6 5 0 0 5 5 5 0 Cysteine-rich KTR Terminase_GpA PF05876.7 CEP20004.1 - 1.9 6.7 9.8 0.39 9.0 1.2 2.2 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Ribosomal_L32p PF01783.18 CEP20004.1 - 2.8 8.1 16.8 12 6.2 1.4 5.2 1 1 3 4 4 4 0 Ribosomal L32p protein family zf-ISL3 PF14690.1 CEP20004.1 - 2.9 8.0 20.9 8.5 6.4 0.4 4.8 5 0 0 5 5 5 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_4 PF13717.1 CEP20004.1 - 3.4 7.4 14.5 2.3 7.9 0.1 4.7 5 0 0 5 5 5 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 CEP20004.1 - 5 6.6 12.4 11 5.6 0.2 5.0 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit DUF1272 PF06906.6 CEP20004.1 - 5.4 6.9 14.8 4.8 7.0 0.1 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1272) zinc_ribbon_5 PF13719.1 CEP20004.1 - 7.7 6.1 14.5 4.8 6.8 0.1 4.7 5 0 0 5 5 5 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.7 CEP20004.1 - 8 6.6 21.4 15 5.8 0.2 5.0 5 0 0 5 5 5 0 Zinc-binding domain of primase-helicase zf-B_box PF00643.19 CEP20004.1 - 8.6 6.3 30.0 4 7.3 0.6 5.2 5 0 0 5 5 5 0 B-box zinc finger rve PF00665.21 CEP20006.1 - 3.1e-11 43.4 0.0 5.5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Fib_alpha PF08702.5 CEP20007.1 - 0.043 13.9 0.3 0.068 13.2 0.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.11 CEP20008.1 - 5.5e-53 179.9 30.1 5.5e-53 179.9 20.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEP20008.1 - 1.4e-15 56.8 7.2 1.4e-15 56.8 5.0 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 CEP20008.1 - 3.7e-06 25.4 3.5 3.7e-06 25.4 2.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CEP20008.1 - 0.011 13.9 5.6 0.016 13.3 0.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2373 PF10180.4 CEP20009.1 - 5.5e-18 64.2 1.3 1.1e-17 63.3 0.9 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Polysacc_deac_1 PF01522.16 CEP20009.1 - 4e-12 45.8 0.1 1.5e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 Polysaccharide deacetylase PTPlike_phytase PF14566.1 CEP20009.1 - 0.29 11.1 3.6 0.94 9.5 2.5 2.0 1 1 0 1 1 1 0 Inositol hexakisphosphate DUF2183 PF09949.4 CEP20010.1 - 0.27 11.2 2.7 0.3 11.0 0.1 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2183) CENP-B_dimeris PF09026.5 CEP20010.1 - 7.7 6.8 9.6 15 5.9 6.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HypA PF01155.14 CEP20011.1 - 0.0035 17.0 14.4 0.091 12.4 0.3 3.5 3 1 0 3 3 3 1 Hydrogenase expression/synthesis hypA family zf-CCHC PF00098.18 CEP20011.1 - 0.0037 17.1 0.3 0.0037 17.1 0.2 4.1 5 0 0 5 5 4 2 Zinc knuckle zf-ribbon_3 PF13248.1 CEP20011.1 - 0.0082 15.3 10.4 0.43 9.8 0.1 4.3 4 0 0 4 4 4 1 zinc-ribbon domain Ribosomal_L32p PF01783.18 CEP20011.1 - 0.057 13.6 9.3 2.4 8.3 0.0 3.4 2 1 2 4 4 4 0 Ribosomal L32p protein family zinc_ribbon_2 PF13240.1 CEP20011.1 - 0.062 12.8 9.2 0.61 9.6 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 CEP20011.1 - 0.11 12.2 17.1 0.67 9.8 2.1 3.8 2 2 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 CEP20011.1 - 0.22 11.2 9.5 0.96 9.1 0.1 3.9 4 0 0 4 4 4 0 Nudix N-terminal DUF164 PF02591.10 CEP20011.1 - 0.24 11.2 8.8 0.82 9.5 0.4 4.0 4 0 0 4 4 4 0 Putative zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 CEP20011.1 - 0.47 10.2 4.2 7 6.5 0.1 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-CHY PF05495.7 CEP20011.1 - 0.69 10.1 15.7 1.5 9.0 0.6 3.8 3 1 0 3 3 3 0 CHY zinc finger Prok-RING_1 PF14446.1 CEP20011.1 - 0.98 9.2 20.7 0.16 11.7 0.6 4.5 3 2 2 5 5 5 0 Prokaryotic RING finger family 1 Sgf11 PF08209.6 CEP20011.1 - 1.3 8.3 12.2 2.8 7.3 0.2 3.8 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 CEP20011.1 - 1.9 8.9 13.4 5.2 7.5 0.0 4.5 4 2 1 5 5 5 0 Zinc-finger double domain FYDLN_acid PF09538.5 CEP20011.1 - 2.1 8.9 5.4 0.68 10.5 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) GATA PF00320.22 CEP20011.1 - 2.1 7.7 8.8 12 5.3 0.0 4.0 4 0 0 4 4 4 0 GATA zinc finger OrfB_Zn_ribbon PF07282.6 CEP20011.1 - 3.8 7.2 16.2 4.6 6.9 1.1 3.7 3 1 0 3 3 3 0 Putative transposase DNA-binding domain zf-B_box PF00643.19 CEP20011.1 - 4.8 7.1 20.5 1.3 8.9 0.2 4.2 4 0 0 4 4 4 0 B-box zinc finger YhfH PF14149.1 CEP20011.1 - 6.1 6.7 8.9 19 5.1 0.1 3.4 3 0 0 3 3 3 0 YhfH-like protein zinc-ribbons_6 PF07191.7 CEP20011.1 - 6.9 6.5 13.7 9 6.1 1.8 3.5 3 1 0 3 3 3 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.2 CEP20011.1 - 7.7 6.4 20.9 1.3 8.9 1.3 4.1 3 1 1 4 4 4 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 CEP20011.1 - 8.6 6.1 11.1 22 4.8 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Peptidase_C1_2 PF03051.10 CEP20012.1 - 3.8e-167 556.2 0.2 4.5e-167 556.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CEP20012.1 - 0.0053 16.6 3.1 0.44 10.3 0.2 2.7 3 0 0 3 3 3 2 Papain family cysteine protease Pcc1 PF09341.5 CEP20013.1 - 2.3e-20 72.4 0.1 2.7e-20 72.1 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Ras PF00071.17 CEP20014.1 - 4.5e-55 185.4 0.2 5.1e-55 185.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEP20014.1 - 1.9e-21 76.7 0.5 2.6e-21 76.3 0.1 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEP20014.1 - 5.4e-08 32.2 0.2 7.3e-08 31.8 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEP20014.1 - 3.6e-07 29.8 0.2 9e-07 28.5 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEP20014.1 - 2.1e-06 27.7 0.1 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CEP20014.1 - 0.0079 14.9 0.2 0.74 8.4 0.0 2.7 1 1 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CEP20014.1 - 0.065 12.3 0.2 0.091 11.8 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CEP20014.1 - 0.16 12.1 0.4 5.8 7.0 0.2 2.6 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.2 CEP20015.1 - 1.3e-06 27.9 10.8 0.00042 19.8 0.3 3.8 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEP20015.1 - 0.0068 16.1 13.9 0.91 9.3 0.1 4.9 4 2 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CEP20015.1 - 0.01 15.8 15.6 3.8 7.8 0.1 5.8 5 0 0 5 5 5 0 Leucine Rich repeat Rad60-SLD PF11976.3 CEP20017.1 - 0.045 13.4 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TORC_N PF12884.2 CEP20017.1 - 0.12 12.8 0.1 0.98 9.9 0.0 2.5 3 0 0 3 3 3 0 Transducer of regulated CREB activity, N terminus Exo_endo_phos PF03372.18 CEP20019.1 - 3.3e-08 33.7 0.0 4.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CEP20019.1 - 8.1e-06 25.3 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RFPL3_antisense PF10489.4 CEP20021.1 - 0.052 13.3 0.1 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense Myb_DNA-bind_4 PF13837.1 CEP20022.1 - 0.00015 21.8 0.2 0.00021 21.3 0.1 1.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Plant_tran PF04827.9 CEP20023.1 - 1.1e-35 122.9 0.1 1.9e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DUF2009 PF09418.5 CEP20023.1 - 0.049 12.3 0.4 0.061 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) HTH_Tnp_1 PF01527.15 CEP20025.1 - 0.078 12.9 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.1 CEP20025.1 - 0.11 13.3 0.0 1.9 9.3 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain DUF1454 PF07305.7 CEP20028.1 - 0.066 12.3 2.8 0.1 11.6 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) ABC2_membrane_3 PF12698.2 CEP20028.1 - 2 7.3 8.7 2.8 6.8 6.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2681 PF10883.3 CEP20028.1 - 8.8 6.6 15.5 0.79 9.9 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DDE_3 PF13358.1 CEP20029.1 - 6.6e-06 25.9 0.0 1.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L31e PF01198.14 CEP20029.1 - 0.026 14.1 0.1 0.06 13.0 0.1 1.7 1 1 0 1 1 1 0 Ribosomal protein L31e F-box-like PF12937.2 CEP20030.1 - 3.5e-05 23.4 0.1 0.00011 21.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like Mpp10 PF04006.7 CEP20032.1 - 1.9e-128 429.4 88.5 2.4e-128 429.1 61.3 1.0 1 0 0 1 1 1 1 Mpp10 protein PLDc PF00614.17 CEP20033.1 - 1e-15 56.9 0.5 7.5e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CEP20033.1 - 4.1e-14 52.4 1.0 1.2e-08 34.7 0.0 3.7 4 1 0 4 4 4 2 PLD-like domain PX PF00787.19 CEP20033.1 - 4.5e-08 32.8 2.2 4.5e-08 32.8 1.6 3.8 4 0 0 4 4 4 1 PX domain Dynamin_N PF00350.18 CEP20034.1 - 2.5e-19 69.6 0.9 2.5e-19 69.6 0.6 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CEP20034.1 - 1.2e-12 47.8 1.8 6.6e-11 42.1 0.7 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEP20034.1 - 5e-07 29.3 7.4 2e-06 27.3 4.1 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CEP20034.1 - 0.00063 20.2 3.1 0.02 15.4 0.5 3.0 2 1 0 2 2 2 1 Miro-like protein cobW PF02492.14 CEP20034.1 - 0.0029 17.0 7.5 0.061 12.7 2.2 3.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 CEP20034.1 - 0.0086 16.0 2.6 0.026 14.4 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 CEP20034.1 - 0.0092 15.4 1.5 4 6.9 0.0 3.3 4 0 0 4 4 4 2 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CEP20034.1 - 0.013 15.0 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 CEP20034.1 - 0.014 14.6 1.7 2.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynactin_p22 PF07426.6 CEP20034.1 - 0.016 14.5 3.3 0.06 12.6 2.3 2.0 1 0 0 1 1 1 0 Dynactin subunit p22 IIGP PF05049.8 CEP20034.1 - 0.019 13.7 8.7 0.051 12.3 0.1 3.1 3 1 0 3 3 3 0 Interferon-inducible GTPase (IIGP) MCPVI PF02993.9 CEP20034.1 - 0.039 14.0 2.3 0.1 12.7 1.6 1.6 1 0 0 1 1 1 0 Minor capsid protein VI AAA_22 PF13401.1 CEP20034.1 - 0.052 13.6 0.1 0.44 10.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CEP20034.1 - 0.36 10.4 3.5 0.42 10.2 0.0 2.7 3 1 0 3 3 3 0 Archaeal ATPase INCENP_ARK-bind PF03941.10 CEP20035.1 - 7.6e-09 35.2 0.0 2.3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region She9_MDM33 PF05546.6 CEP20036.1 - 2.4e-65 219.9 12.9 2.4e-65 219.9 9.0 1.8 2 0 0 2 2 2 1 She9 / Mdm33 family Drf_FH3 PF06367.11 CEP20036.1 - 0.012 14.9 0.1 0.012 14.9 0.1 2.7 1 1 2 3 3 3 0 Diaphanous FH3 Domain DUF2120 PF09893.4 CEP20036.1 - 0.12 12.2 4.0 1.9 8.4 0.7 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF2762 PF10960.3 CEP20036.1 - 4.2 7.1 10.9 0.22 11.2 0.3 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2762) DUF1664 PF07889.7 CEP20036.1 - 5.4 6.8 11.0 0.33 10.7 1.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF1098 PF06497.6 CEP20036.1 - 5.6 7.0 8.8 0.74 9.9 2.4 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1098) UBN_AB PF14075.1 CEP20037.1 - 1.5e-12 47.6 1.9 1.5e-12 47.6 1.3 2.4 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.5 CEP20037.1 - 2.9e-09 36.6 12.9 7.1e-09 35.4 8.9 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain zf-Tim10_DDP PF02953.10 CEP20038.1 - 8.4e-21 73.0 2.5 1.1e-20 72.6 1.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vps54 PF07928.7 CEP20038.1 - 0.084 12.9 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Vps54-like protein DUF842 PF05811.8 CEP20038.1 - 0.1 12.0 2.9 0.17 11.3 2.0 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) PapB PF03333.8 CEP20040.1 - 0.032 14.0 0.2 0.082 12.7 0.1 1.7 1 1 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein Hydrolase_4 PF12146.3 CEP20040.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase RGS PF00615.14 CEP20041.1 - 0.00037 20.5 0.0 0.00088 19.3 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF3671 PF12420.3 CEP20041.1 - 0.019 14.9 0.8 0.019 14.9 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF4050 PF13259.1 CEP20042.1 - 0.014 15.3 0.5 0.015 15.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Endonuc_Holl PF10107.4 CEP20042.1 - 0.032 13.9 1.2 0.04 13.6 0.9 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase SF-assemblin PF06705.6 CEP20042.1 - 0.035 13.2 1.8 0.062 12.4 1.3 1.4 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF3106 PF11304.3 CEP20042.1 - 0.038 14.4 3.3 0.038 14.4 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) OmpH PF03938.9 CEP20042.1 - 0.044 13.7 7.2 0.06 13.2 5.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 CEP20042.1 - 0.092 11.6 1.4 0.095 11.6 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MRP-L28 PF09812.4 CEP20042.1 - 0.36 10.6 5.4 0.5 10.1 3.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 PolyA_pol_arg_C PF12626.2 CEP20042.1 - 0.7 9.5 7.3 0.99 9.0 5.1 1.2 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus IncA PF04156.9 CEP20042.1 - 5.9 6.4 9.8 8.5 5.9 6.8 1.3 1 0 0 1 1 1 0 IncA protein BUD22 PF09073.5 CEP20045.1 - 0.078 12.0 16.0 0.098 11.7 11.1 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.4 CEP20045.1 - 0.18 10.0 18.3 0.21 9.8 12.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4518 PF15008.1 CEP20045.1 - 0.2 10.6 1.1 0.26 10.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) SR-25 PF10500.4 CEP20045.1 - 2.8 7.3 12.1 3.9 6.8 8.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phage_integrase PF00589.17 CEP20046.1 - 4.5e-05 23.1 0.1 6.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family Integrase_1 PF12835.2 CEP20046.1 - 0.013 15.2 0.1 0.025 14.3 0.0 1.7 2 0 0 2 2 2 0 Integrase Phage_int_SAM_4 PF13495.1 CEP20047.1 - 0.0036 17.6 1.9 0.0051 17.1 1.3 1.3 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DNA_pol_viral_C PF00336.13 CEP20048.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Sif PF06767.6 CEP20049.1 - 0.069 11.8 0.0 0.07 11.8 0.0 1.0 1 0 0 1 1 1 0 Sif protein Aldo_ket_red PF00248.16 CEP20050.1 - 1.2e-26 93.2 0.1 3.4e-24 85.1 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family zf-C2H2_6 PF13912.1 CEP20051.1 - 0.0059 16.4 0.2 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CEP20051.1 - 0.057 13.7 0.3 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger p450 PF00067.17 CEP20052.1 - 7e-80 268.7 0.3 9.2e-80 268.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSP20 PF00011.16 CEP20053.1 - 7e-22 77.2 0.7 9.1e-14 51.1 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Ribosomal_L36 PF00444.13 CEP20054.1 - 1.7e-18 66.2 11.3 2.2e-18 65.9 7.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 WD40 PF00400.27 CEP20055.1 - 3.9e-29 99.4 18.0 4.1e-07 29.6 0.1 10.4 11 0 0 11 11 11 5 WD domain, G-beta repeat CPSF_A PF03178.10 CEP20055.1 - 0.0038 16.3 0.7 2.1 7.3 0.0 2.9 3 0 0 3 3 3 2 CPSF A subunit region tRNA-synt_1 PF00133.17 CEP20056.1 - 8.4e-208 691.1 0.0 3.7e-207 689.0 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CEP20056.1 - 2.9e-37 127.8 0.1 5.9e-37 126.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CEP20056.1 - 5.3e-15 54.9 1.0 5.6e-07 28.5 0.0 4.5 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CEP20056.1 - 2.4e-10 40.0 0.3 1.1e-07 31.3 0.1 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 NAD_binding_10 PF13460.1 CEP20056.1 - 3.3e-10 40.2 0.0 1.8e-08 34.6 0.0 2.9 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CEP20056.1 - 6.7e-06 25.7 0.0 1.9e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CEP20056.1 - 0.004 17.0 0.0 0.0089 15.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 CEP20056.1 - 0.0083 14.8 0.0 0.029 13.0 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family tRNA-synt_1e PF01406.14 CEP20056.1 - 0.046 12.8 0.0 0.6 9.1 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CEP20056.1 - 0.059 12.1 0.0 0.38 9.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) Luciferase_N PF05295.6 CEP20058.1 - 0.063 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain DUF2400 PF09674.5 CEP20058.1 - 0.094 12.3 0.5 0.14 11.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) RasGEF PF00617.14 CEP20059.1 - 2e-43 148.3 0.3 3.4e-43 147.5 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain MscS_porin PF12795.2 CEP20059.1 - 0.01 15.1 0.1 0.025 13.9 0.1 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Usp PF00582.21 CEP20061.1 - 5.1e-06 26.7 0.1 1e-05 25.7 0.0 1.5 2 0 0 2 2 2 1 Universal stress protein family zf-C2H2 PF00096.21 CEP20062.1 - 0.00014 22.0 20.4 0.0067 16.7 0.3 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP20062.1 - 0.00015 21.8 15.2 0.11 12.8 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP20062.1 - 0.0041 17.2 1.5 1.5 9.1 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CEP20062.1 - 0.022 15.0 5.1 0.12 12.7 0.6 3.5 4 0 0 4 4 4 0 Zinc-finger double domain Gti1_Pac2 PF09729.4 CEP20063.1 - 6.8e-61 205.0 0.1 6.8e-61 205.0 0.0 2.5 2 1 0 2 2 2 1 Gti1/Pac2 family PAT1 PF09770.4 CEP20063.1 - 0.08 11.1 20.7 0.11 10.7 14.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 CEP20064.1 - 1.2e-54 185.1 0.0 1.7e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP20064.1 - 4.7e-28 97.9 0.0 6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CEP20064.1 - 0.00069 18.5 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CEP20064.1 - 0.0039 16.9 0.1 0.015 15.0 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family His_Phos_1 PF00300.17 CEP20066.1 - 1.6e-15 57.5 0.0 2.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CEP20066.1 - 0.00027 20.3 0.1 0.0005 19.5 0.1 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) rve PF00665.21 CEP20067.1 - 5e-09 36.3 0.0 7.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF1961 PF09224.6 CEP20067.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) Baculo_PEP_C PF04513.7 CEP20068.1 - 0.19 11.5 5.2 0.23 11.2 3.6 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDE_3 PF13358.1 CEP20071.1 - 3e-27 95.1 0.0 7.1e-27 93.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease F-box-like PF12937.2 CEP20071.1 - 1.6e-05 24.5 0.1 4.1e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEP20071.1 - 4.6e-05 22.9 0.1 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUSP PF06337.7 CEP20071.1 - 0.0011 19.3 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 DUSP domain Elongin_A PF06881.6 CEP20071.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A C1_1 PF00130.17 CEP20071.1 - 5.7 6.7 13.1 0.96 9.2 2.9 3.5 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RE_Bpu10I PF09549.5 CEP20072.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Bpu10I restriction endonuclease MULE PF10551.4 CEP20073.1 - 3e-08 33.7 0.2 7.7e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CEP20073.1 - 3.2e-06 25.9 0.5 6.2e-06 24.9 0.4 1.4 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.1 CEP20073.1 - 0.016 15.1 0.1 7 6.6 0.1 2.8 2 0 0 2 2 2 0 DDE domain AAT PF03417.11 CEP20073.1 - 0.018 14.4 0.5 0.047 13.1 0.4 1.7 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Cytadhesin_P30 PF07271.6 CEP20075.1 - 0.063 12.5 6.3 0.12 11.5 4.4 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 ODC_AZ PF02100.12 CEP20077.1 - 7.7e-13 47.8 0.0 1.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF3014 PF11219.3 CEP20078.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) RVT_1 PF00078.22 CEP20079.1 - 4e-32 111.3 0.0 1.2e-31 109.7 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP20079.1 - 5.7e-06 26.4 0.3 1.2e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CEP20079.1 - 2.7e-05 24.3 0.2 2.7e-05 24.3 0.1 2.8 2 1 1 3 3 3 1 zinc-binding in reverse transcriptase DDE_3 PF13358.1 CEP20079.1 - 0.0042 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease YL1 PF05764.8 CEP20079.1 - 0.038 13.5 7.5 0.086 12.4 5.2 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Mpv17_PMP22 PF04117.7 CEP20081.1 - 1.1e-27 95.4 1.2 2.5e-27 94.2 0.8 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-C2H2 PF00096.21 CEP20082.1 - 5.4e-07 29.5 7.9 0.00025 21.1 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEP20082.1 - 2.6e-06 27.4 1.8 2.6e-06 27.4 1.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEP20082.1 - 7.9e-06 25.8 6.2 0.0024 18.0 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEP20082.1 - 0.047 13.5 1.9 0.14 12.1 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger ANTH PF07651.11 CEP20084.1 - 8e-35 119.9 5.6 2.8e-33 114.8 1.5 2.3 1 1 1 2 2 2 2 ANTH domain FlgN PF05130.7 CEP20084.1 - 0.071 13.3 0.6 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 FlgN protein DUF1129 PF06570.6 CEP20085.1 - 0.62 9.3 0.0 0.62 9.3 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) Ribosomal_L5_C PF00673.16 CEP20086.1 - 4.1e-24 84.1 0.0 5.9e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CEP20086.1 - 5.3e-19 67.7 0.1 1.5e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 HLH PF00010.21 CEP20087.1 - 8.8e-13 47.7 0.2 8.8e-13 47.7 0.1 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain His_Phos_2 PF00328.17 CEP20088.1 - 1.2e-31 110.2 0.0 1.6e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 CEP20088.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF4366 PF14283.1 CEP20090.1 - 0.00016 21.1 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.1 CEP20090.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family zf-DHHC PF01529.15 CEP20090.1 - 0.027 13.8 0.2 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase PBP1_TM PF14812.1 CEP20090.1 - 0.057 13.7 6.1 0.13 12.5 4.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chordopox_A33R PF05966.7 CEP20090.1 - 0.091 11.5 0.1 0.091 11.5 0.1 1.6 2 0 0 2 2 2 0 Chordopoxvirus A33R protein FAM176 PF14851.1 CEP20090.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.6 2 0 0 2 2 2 0 FAM176 family stn_TNFRSF12A PF12191.3 CEP20090.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.3 3 1 1 4 4 4 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Alpha_GJ PF03229.8 CEP20090.1 - 0.28 11.5 9.1 7.1 6.9 0.0 2.6 2 1 0 2 2 2 0 Alphavirus glycoprotein J DSPc PF00782.15 CEP20091.1 - 3.8e-07 29.7 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEP20091.1 - 2.3e-06 27.1 0.0 5.5e-06 25.8 0.0 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Deltaretro_Tax PF05599.6 CEP20092.1 - 0.072 13.4 0.3 0.09 13.0 0.2 1.2 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Glyco_hydro_47 PF01532.15 CEP20095.1 - 3.9e-165 549.8 0.0 4.6e-165 549.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 CEP20095.1 - 0.00057 19.3 0.9 0.15 11.4 0.0 2.7 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.6 CEP20095.1 - 0.032 13.2 0.6 1.5 7.7 0.0 2.9 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_88 PF07470.8 CEP20095.1 - 0.05 12.6 0.1 0.45 9.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Mito_carr PF00153.22 CEP20096.1 - 2.4e-56 187.4 1.6 8.2e-21 73.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Polysacc_deac_1 PF01522.16 CEP20096.1 - 0.00026 20.6 0.0 0.00098 18.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase PIF1 PF05970.9 CEP20097.1 - 0.004 16.1 0.0 0.0054 15.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DDE_1 PF03184.14 CEP20099.1 - 1.4e-29 102.7 0.1 1.9e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 CEP20099.1 - 0.00051 19.8 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1820 PF08850.6 CEP20099.1 - 0.094 12.8 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1820) Aha1_N PF09229.6 CEP20100.1 - 3.6e-32 111.0 0.1 7e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF727 PF05303.7 CEP20101.1 - 1.3e-09 37.7 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Desmo_N PF06771.6 CEP20101.1 - 0.048 13.6 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus DUF3313 PF11769.3 CEP20101.1 - 0.073 12.4 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Arrestin_N PF00339.24 CEP20102.1 - 1.4e-07 31.4 0.0 1.4e-07 31.4 0.0 2.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEP20102.1 - 1.4e-06 28.4 0.0 6.4e-05 23.0 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain RHD3 PF05879.7 CEP20102.1 - 0.018 13.0 2.6 0.89 7.3 0.1 2.3 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) LDB19 PF13002.2 CEP20102.1 - 0.045 13.2 0.1 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like MGC-24 PF05283.6 CEP20102.1 - 2 8.2 11.4 3.6 7.3 7.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) SSP160 PF06933.6 CEP20102.1 - 5.4 4.8 13.4 9.5 4.0 9.3 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UreD PF01774.12 CEP20103.1 - 1.5e-45 155.2 0.0 1.9e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein CoA_binding PF02629.14 CEP20104.1 - 1.7e-25 89.3 0.7 1.7e-25 89.3 0.5 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CEP20104.1 - 2.4e-22 79.2 0.2 4.1e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CEP20104.1 - 1.7e-05 24.4 0.0 3.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CEP20104.1 - 0.0015 18.6 0.0 0.0067 16.5 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain IL12p40_C PF10420.4 CEP20105.1 - 0.047 13.8 1.8 0.49 10.5 0.6 2.6 2 1 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus CDK2AP PF09806.4 CEP20105.1 - 0.2 11.8 5.0 0.35 11.0 3.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CEP20105.1 - 2.8 7.3 14.5 6.3 6.1 10.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OrfB_Zn_ribbon PF07282.6 CEP20106.1 - 0.00085 18.9 0.1 0.00085 18.9 0.1 2.3 3 0 0 3 3 3 1 Putative transposase DNA-binding domain zf-CCHC_4 PF14392.1 CEP20106.1 - 0.048 13.3 0.5 5.2 6.8 0.2 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 CEP20106.1 - 0.051 13.5 1.6 0.051 13.5 1.1 2.7 3 0 0 3 3 3 0 Zinc knuckle zf-RVT PF13966.1 CEP20107.1 - 9.9e-07 28.9 1.5 1.6e-06 28.3 0.1 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Endonuclease_7 PF02945.10 CEP20107.1 - 0.096 12.4 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Recombination endonuclease VII RVT_1 PF00078.22 CEP20108.1 - 5.7e-22 78.1 0.1 6.8e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Imm11 PF15563.1 CEP20108.1 - 0.01 14.9 0.3 0.016 14.2 0.1 1.4 1 1 0 1 1 1 0 Immunity protein 11 Ribosomal_L13e PF01294.13 CEP20112.1 - 1.6e-76 255.7 5.2 2.3e-76 255.2 3.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e bZIP_1 PF00170.16 CEP20113.1 - 4e-10 39.5 12.6 7.1e-10 38.7 8.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEP20113.1 - 2.4e-06 27.2 13.4 5.6e-06 26.0 9.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DUF4631 PF15450.1 CEP20113.1 - 0.0055 15.0 3.9 0.0074 14.6 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) HALZ PF02183.13 CEP20113.1 - 0.011 15.4 3.4 0.023 14.4 2.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.12 CEP20113.1 - 0.013 15.7 6.9 0.033 14.4 4.8 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor XhlA PF10779.4 CEP20113.1 - 2.3 8.1 4.9 1.2 9.1 1.4 1.9 2 0 0 2 2 2 0 Haemolysin XhlA EPL1 PF10513.4 CEP20114.1 - 2.2 8.5 12.7 1.3 9.2 6.7 1.9 1 1 1 2 2 2 0 Enhancer of polycomb-like Mito_carr PF00153.22 CEP20116.1 - 2.6e-65 216.1 1.1 9.4e-23 79.7 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein Glucosamine_iso PF01182.15 CEP20116.1 - 1.1e-21 77.5 0.0 1.7e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RINGv PF12906.2 CEP20117.1 - 6.2e-08 32.5 9.5 1e-07 31.8 6.6 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CEP20117.1 - 0.00012 21.8 6.4 0.00022 21.0 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 CEP20117.1 - 0.00085 19.2 5.8 0.0017 18.3 4.0 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 CEP20117.1 - 0.092 12.3 4.8 0.19 11.3 3.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CEP20117.1 - 0.17 11.5 4.1 0.3 10.7 2.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEP20117.1 - 2.5 8.1 6.3 5 7.2 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fip1 PF05182.8 CEP20118.1 - 6.6e-25 86.1 0.6 1.2e-24 85.2 0.4 1.4 1 0 0 1 1 1 1 Fip1 motif Lin-8 PF03353.10 CEP20118.1 - 5.7 6.1 13.6 11 5.2 9.4 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.6 CEP20118.1 - 5.9 4.6 13.3 11 3.6 9.2 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CRM1_C PF08767.6 CEP20119.1 - 5.7e-61 206.1 11.7 5.7e-61 206.1 8.1 4.1 4 2 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CEP20119.1 - 9.9e-32 109.8 6.1 9.9e-32 109.8 4.2 5.0 3 2 3 6 6 6 1 Exportin 1-like protein IBN_N PF03810.14 CEP20119.1 - 1.9e-10 40.5 5.9 3e-10 39.8 0.7 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Dfp1_Him1_M PF08630.5 CEP20119.1 - 0.01 15.5 0.2 0.71 9.6 0.0 3.0 2 0 0 2 2 2 0 Dfp1/Him1, central region SAP PF02037.22 CEP20121.1 - 9.7e-12 44.0 0.1 1.7e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 SAP domain DUF4201 PF13870.1 CEP20123.1 - 0.00079 18.9 4.4 0.00079 18.9 3.1 4.2 2 1 2 4 4 4 1 Domain of unknown function (DUF4201) AAA_13 PF13166.1 CEP20123.1 - 0.0029 16.1 16.6 0.0029 16.1 11.5 2.1 1 1 0 2 2 2 1 AAA domain Synaptonemal_3 PF15191.1 CEP20123.1 - 0.22 11.3 4.3 0.24 11.1 0.5 2.4 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 CENP-F_leu_zip PF10473.4 CEP20123.1 - 0.56 10.0 29.2 0.99 9.2 3.7 3.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.7 CEP20123.1 - 0.58 8.5 5.2 1 7.6 3.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nup54 PF13874.1 CEP20123.1 - 1.8 8.1 23.0 1.2 8.8 0.6 3.9 3 1 1 4 4 4 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 CEP20123.1 - 3.4 7.4 17.8 0.092 12.5 3.9 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 CEP20123.1 - 3.7 7.5 7.0 22 5.2 0.6 4.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat GCR1_C PF12550.3 CEP20124.1 - 3.6e-38 129.2 0.6 6.3e-24 83.6 0.2 3.3 2 0 0 2 2 2 2 Transcriptional activator of glycolytic enzymes DNA_pol_A_exo1 PF01612.15 CEP20124.1 - 1.6e-16 60.3 0.1 1.6e-16 60.3 0.1 2.2 2 0 0 2 2 2 1 3'-5' exonuclease YL1 PF05764.8 CEP20126.1 - 0.44 10.1 2.7 0.49 9.9 0.2 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Sec66 PF09802.4 CEP20128.1 - 3.3e-39 134.2 4.6 6.4e-39 133.3 3.2 1.5 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 Sporozoite_P67 PF05642.6 CEP20128.1 - 0.6 7.9 5.6 0.71 7.6 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MgtE PF01769.11 CEP20129.1 - 0.015 15.6 1.7 0.015 15.6 1.2 2.7 2 1 1 3 3 3 0 Divalent cation transporter Apq12 PF12716.2 CEP20130.1 - 0.001 18.7 15.0 0.0018 17.9 10.4 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis 7tm_7 PF08395.7 CEP20130.1 - 0.0026 16.8 8.6 0.0028 16.7 6.0 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor DUF3149 PF11346.3 CEP20130.1 - 6.5 6.3 10.7 0.19 11.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) p450 PF00067.17 CEP20131.1 - 1.3e-73 248.1 0.0 1.7e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GCR1_C PF12550.3 CEP20132.1 - 2.3e-21 75.4 3.6 8.3e-21 73.6 2.5 2.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_5 PF08360.6 CEP20132.1 - 0.0079 16.1 2.4 0.015 15.2 0.6 2.3 2 0 0 2 2 2 1 QacR-like protein, C-terminal region Flavi_capsid PF01003.14 CEP20132.1 - 0.22 11.0 1.3 2 7.9 0.1 2.5 2 0 0 2 2 2 0 Flavivirus capsid protein C Pkinase PF00069.20 CEP20133.1 - 2.8e-70 236.4 0.0 3.8e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP20133.1 - 1.9e-35 122.2 0.0 2.7e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP20133.1 - 3.1e-05 23.0 0.0 4.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RTC4 PF14474.1 CEP20133.1 - 0.12 12.3 0.4 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 RTC4-like domain Pribosyltran_N PF13793.1 CEP20134.1 - 3.4e-46 155.7 2.0 2.1e-45 153.1 0.2 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CEP20134.1 - 6e-43 146.7 8.1 1.3e-36 126.0 1.8 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CEP20134.1 - 6e-13 48.6 0.9 2.4e-12 46.6 0.3 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CEP20134.1 - 0.0034 16.6 2.3 0.012 14.8 0.3 2.2 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase RdRP PF05183.7 CEP20134.1 - 0.035 12.7 0.1 0.048 12.3 0.1 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase UPF0181 PF03701.9 CEP20134.1 - 0.064 12.5 0.7 0.7 9.2 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0181) KH_3 PF13014.1 CEP20135.1 - 0.0048 16.5 0.4 0.01 15.4 0.3 1.6 1 0 0 1 1 1 1 KH domain RGS PF00615.14 CEP20136.1 - 0.00025 21.1 0.0 0.00057 19.9 0.0 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain PDEase_I PF00233.14 CEP20137.1 - 2e-49 168.4 1.4 4.5e-49 167.3 1.0 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CEP20137.1 - 0.032 14.2 0.1 0.07 13.1 0.1 1.6 1 0 0 1 1 1 0 HD domain ChaC PF04752.7 CEP20137.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 ChaC-like protein DUF2914 PF11141.3 CEP20137.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) tRNA_anti-codon PF01336.20 CEP20137.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain LysM PF01476.15 CEP20138.1 - 1e-12 47.7 0.2 2.7e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 LysM domain HTH_28 PF13518.1 CEP20138.1 - 0.044 13.8 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain ATPgrasp_YheCD PF14398.1 CEP20140.1 - 0.035 12.8 0.5 0.065 12.0 0.4 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp Sec2p PF06428.6 CEP20140.1 - 0.049 13.4 0.2 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CDC37_N PF03234.9 CEP20140.1 - 0.08 13.2 2.4 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Ycf34 PF10718.4 CEP20140.1 - 0.095 13.1 0.2 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Hypothetical chloroplast protein Ycf34 DUF948 PF06103.6 CEP20140.1 - 0.1 12.4 2.7 8 6.3 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.4 CEP20140.1 - 7 6.6 8.7 0.17 11.8 0.4 2.3 3 0 0 3 3 3 0 Haemolysin XhlA DDE_Tnp_1_7 PF13843.1 CEP20141.1 - 8.4e-23 80.9 0.0 1e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 tRNA-synt_1g PF09334.6 CEP20143.1 - 1.3e-143 478.4 0.0 1.7e-143 478.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CEP20143.1 - 1.5e-08 33.1 0.0 1.6e-05 23.1 0.0 2.8 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) MetRS-N PF09635.5 CEP20143.1 - 0.011 16.1 0.8 0.023 15.0 0.5 1.6 1 0 0 1 1 1 0 MetRS-N binding domain UPF0547 PF10571.4 CEP20143.1 - 5.3 6.8 7.5 12 5.6 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-H2C2_2 PF13465.1 CEP20144.1 - 4.3e-26 89.8 22.4 5.9e-08 32.6 0.3 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CEP20144.1 - 7.9e-22 76.2 30.4 4.6e-06 26.6 0.9 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEP20144.1 - 2.1e-13 49.5 27.1 0.0015 18.7 1.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEP20144.1 - 0.00018 21.5 8.0 1.2 9.3 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEP20144.1 - 0.011 15.6 16.0 0.22 11.4 0.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-TRAF PF02176.13 CEP20144.1 - 0.1 13.0 0.4 0.1 13.0 0.3 3.2 2 1 1 3 3 3 0 TRAF-type zinc finger TRH PF05438.7 CEP20144.1 - 0.17 11.2 5.0 1.2 8.4 3.5 2.3 1 1 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) zf-met PF12874.2 CEP20144.1 - 0.2 11.9 12.3 17 5.8 0.0 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 CEP20144.1 - 0.86 9.3 10.0 0.65 9.7 0.1 3.7 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger ABC_tran PF00005.22 CEP20145.1 - 9.4e-22 77.7 1.3 2.1e-21 76.6 0.0 2.2 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.18 CEP20145.1 - 1.3e-21 77.2 10.3 1.8e-21 76.7 7.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AOX PF01786.12 CEP20145.1 - 0.056 12.8 0.6 0.1 12.0 0.2 1.6 2 0 0 2 2 2 0 Alternative oxidase PIN_2 PF10130.4 CEP20145.1 - 0.23 11.4 2.6 0.31 11.0 0.7 2.1 2 0 0 2 2 2 0 PIN domain Pkinase PF00069.20 CEP20146.1 - 2.2e-59 200.7 0.0 6.3e-58 195.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP20146.1 - 3.4e-39 134.4 0.0 4.5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP20146.1 - 5.4e-05 22.3 0.0 8.3e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CEP20146.1 - 0.026 13.3 0.1 0.051 12.3 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CEP20146.1 - 0.13 11.9 0.0 0.88 9.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L37e PF01907.14 CEP20147.1 - 1.4e-26 92.0 13.0 2.8e-26 91.0 9.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 CEP20147.1 - 0.00042 20.0 2.2 0.00087 19.0 1.5 1.5 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CEP20147.1 - 0.0095 15.6 0.8 0.017 14.8 0.5 1.6 1 1 0 1 1 1 1 SelR domain HypA PF01155.14 CEP20147.1 - 0.019 14.6 0.8 0.026 14.1 0.5 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 CEP20147.1 - 0.16 11.6 6.0 0.14 11.8 2.8 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Ribosomal_S14 PF00253.16 CEP20147.1 - 0.21 11.0 7.0 0.52 9.7 0.2 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-C4pol PF14260.1 CEP20147.1 - 0.4 10.7 3.9 1.6 8.8 1.7 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta GFA PF04828.9 CEP20147.1 - 0.41 10.6 4.5 1.4 8.8 2.7 2.1 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 CEP20147.1 - 0.53 9.5 3.7 2.1 7.6 2.7 1.9 1 1 1 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 CEP20147.1 - 0.54 9.7 3.6 3 7.4 0.4 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C3HC4_2 PF13923.1 CEP20147.1 - 1.4 8.9 7.7 0.59 10.2 3.7 1.6 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.11 CEP20147.1 - 1.7 8.4 6.2 75 3.1 4.4 2.8 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C3HC4 PF00097.20 CEP20147.1 - 2.2 8.0 6.6 4.3 7.0 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 CEP20147.1 - 2.6 7.6 8.0 4 7.0 3.6 2.5 2 1 1 3 3 3 0 zinc-ribbon domain zf-HYPF PF07503.7 CEP20147.1 - 6.8 6.2 6.5 6.7 6.2 2.9 2.2 2 1 0 2 2 2 0 HypF finger Formyl_trans_N PF00551.14 CEP20149.1 - 5.5e-30 104.2 0.0 8.3e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CEP20149.1 - 4.9e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF2263 PF10021.4 CEP20152.1 - 0.51 10.3 2.3 0.42 10.5 0.2 1.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2263) DUF869 PF05911.6 CEP20153.1 - 0.0009 17.6 3.2 0.0011 17.3 2.2 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) RRN3 PF05327.6 CEP20153.1 - 0.041 12.0 2.2 0.052 11.6 1.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Adaptin_binding PF10199.4 CEP20153.1 - 0.29 11.4 6.9 5.2 7.3 2.4 2.1 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4441 PF14536.1 CEP20153.1 - 0.33 10.9 4.3 0.16 11.9 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4441) DUF4404 PF14357.1 CEP20153.1 - 0.42 11.0 2.7 0.53 10.7 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DDE_Tnp_1_7 PF13843.1 CEP20154.1 - 2.1e-06 27.0 0.0 2.1e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_3 PF13358.1 CEP20155.1 - 6.9e-09 35.5 0.0 1.3e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease rve PF00665.21 CEP20157.1 - 2.6e-19 69.4 0.0 8.4e-19 67.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEP20157.1 - 9.3e-14 51.2 0.1 4.5e-13 49.0 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CEP20157.1 - 1.9e-10 40.2 0.6 4.5e-10 39.0 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 CEP20157.1 - 2.8e-06 27.7 0.0 6.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease 4HBT PF03061.17 CEP20159.1 - 9.3e-11 41.7 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 CEP20159.1 - 6.4e-05 22.0 0.0 0.00066 18.7 0.2 1.9 1 1 1 2 2 2 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 CEP20159.1 - 0.0025 18.2 0.0 0.0042 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily TRAM_LAG1_CLN8 PF03798.11 CEP20160.1 - 3.2e-40 137.8 18.7 3.2e-40 137.8 13.0 2.1 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.6 CEP20160.1 - 1e-15 56.9 1.3 1e-15 56.9 0.9 2.0 2 0 0 2 2 2 1 TRAM1-like protein Reo_sigmaC PF04582.7 CEP20161.1 - 0.0011 18.1 74.9 0.08 12.1 6.5 7.7 2 2 5 8 8 8 7 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 CEP20161.1 - 0.011 15.4 7.8 0.011 15.4 5.4 14.3 4 3 9 14 14 14 0 TATA element modulatory factor 1 DNA binding YvrJ PF12841.2 CEP20161.1 - 7.7 5.9 10.4 5.3 6.4 0.1 5.4 5 0 0 5 5 5 0 YvrJ protein family Methyltransf_31 PF13847.1 CEP20162.1 - 2.4e-08 33.7 0.1 3.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEP20162.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEP20162.1 - 1.5e-07 31.9 0.0 3.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CEP20162.1 - 1.4e-05 24.7 0.1 2.3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.7 CEP20162.1 - 0.00011 22.6 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CEP20162.1 - 0.00014 21.2 0.2 0.0014 17.9 0.1 2.2 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 CEP20162.1 - 0.00096 19.4 0.2 0.0042 17.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEP20162.1 - 0.01 16.3 0.2 0.068 13.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 CEP20162.1 - 0.017 14.3 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain UPF0020 PF01170.13 CEP20162.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Homez PF11569.3 CEP20162.1 - 0.044 12.8 1.2 1 8.4 0.0 3.2 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez PYRIN PF02758.11 CEP20162.1 - 0.64 9.7 4.3 2.5 7.8 0.1 3.1 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain ComC PF03047.9 CEP20162.1 - 7 6.1 7.5 0.17 11.3 0.3 2.1 2 0 0 2 2 1 0 COMC family Aa_trans PF01490.13 CEP20163.1 - 1.2e-48 165.6 32.6 1.4e-48 165.3 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2353 PF09789.4 CEP20164.1 - 0.016 14.5 0.1 0.018 14.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) WD40 PF00400.27 CEP20165.1 - 1.4e-14 53.2 8.7 0.0032 17.2 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Dynein_IC2 PF11540.3 CEP20165.1 - 0.00068 18.9 0.2 0.0015 17.8 0.1 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 PQQ_3 PF13570.1 CEP20165.1 - 0.051 13.8 0.2 2.5 8.4 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain OmpH PF03938.9 CEP20165.1 - 2.7 7.9 13.6 7.8 6.4 5.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3340 PF11818.3 CEP20165.1 - 2.8 7.8 15.8 1.5 8.7 5.5 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Phage_int_SAM_5 PF13102.1 CEP20165.1 - 2.9 7.9 11.4 0.4 10.6 2.3 2.3 2 0 0 2 2 2 0 Phage integrase SAM-like domain Usp PF00582.21 CEP20165.1 - 3.4 7.8 5.0 27 4.9 0.1 2.5 2 0 0 2 2 2 0 Universal stress protein family BRCT PF00533.21 CEP20166.1 - 0.019 15.0 0.1 0.61 10.2 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Cupin_8 PF13621.1 CEP20167.1 - 6.7e-24 84.7 0.3 1.4e-23 83.7 0.2 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CEP20167.1 - 1.1e-16 61.1 0.0 3.8e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Pkinase PF00069.20 CEP20168.1 - 2e-64 217.2 0.0 3e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEP20168.1 - 1.5e-35 122.5 0.0 2.2e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEP20168.1 - 7.5e-08 31.6 0.0 1.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEP20168.1 - 0.0051 15.8 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CEP20168.1 - 0.019 13.7 0.1 0.031 13.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 CEP20168.1 - 0.026 14.2 0.5 0.047 13.4 0.3 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PfkB PF00294.19 CEP20168.1 - 0.12 11.5 0.1 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Myosin_head PF00063.16 CEP20169.1 - 8.4e-231 767.7 4.2 8.4e-231 767.7 2.9 2.3 2 1 0 2 2 2 1 Myosin head (motor domain) RNA_helicase PF00910.17 CEP20169.1 - 0.069 13.3 0.5 9.2 6.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_29 PF13555.1 CEP20169.1 - 0.16 11.4 0.0 0.49 9.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IQ PF00612.22 CEP20169.1 - 0.18 11.4 3.1 0.13 11.9 0.2 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.1 CEP20169.1 - 0.32 10.9 0.0 0.32 10.9 0.0 3.3 2 1 0 2 2 2 0 AAA ATPase domain EcsC PF12787.2 CEP20170.1 - 0.049 13.0 9.0 0.24 10.7 2.9 2.2 2 0 0 2 2 2 0 EcsC protein family DUF3371 PF11851.3 CEP20170.1 - 2.3 8.9 21.3 0.069 13.8 4.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) Spt20 PF12090.3 CEP20170.1 - 2.4 7.4 11.2 0.5 9.7 0.4 2.3 2 0 0 2 2 2 0 Spt20 family DUF4414 PF14377.1 CEP20170.1 - 6.4 6.7 19.4 12 5.8 8.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) DUF605 PF04652.11 CEP20170.1 - 6.4 6.0 14.7 4.6 6.5 2.1 2.2 2 0 0 2 2 2 0 Vta1 like Dynamin_M PF01031.15 CEP20171.1 - 2.1e-106 355.0 0.4 2.1e-106 355.0 0.2 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CEP20171.1 - 2.1e-55 187.1 0.8 4.8e-55 185.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CEP20171.1 - 9e-30 102.4 6.2 9e-30 102.4 4.3 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CEP20171.1 - 0.0013 18.6 2.2 0.0063 16.4 0.3 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CEP20171.1 - 0.025 15.0 0.0 0.065 13.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 CEP20171.1 - 0.059 12.6 0.1 8.8 5.5 0.1 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF972 PF06156.8 CEP20172.1 - 0.13 12.5 11.4 1.2 9.5 0.9 3.7 3 2 0 3 3 3 0 Protein of unknown function (DUF972) HALZ PF02183.13 CEP20172.1 - 1.3 8.8 8.3 0.97 9.2 0.9 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Noelin-1 PF12308.3 CEP20172.1 - 1.5 8.6 5.6 7.6 6.3 0.1 3.3 3 0 0 3 3 3 0 Neurogenesis glycoprotein zf-CCHC PF00098.18 CEP20173.1 - 0.025 14.5 8.1 1.1 9.2 0.1 2.5 1 1 1 2 2 2 0 Zinc knuckle DUF2721 PF11026.3 CEP20173.1 - 0.83 9.2 1.6 1.8 8.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) zf-CCHC_4 PF14392.1 CEP20173.1 - 3 7.5 13.7 0.97 9.1 0.5 2.9 2 1 1 3 3 3 0 Zinc knuckle bZIP_Maf PF03131.12 CEP20174.1 - 0.00019 21.6 8.1 0.00019 21.6 5.6 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 CEP20174.1 - 0.00048 20.0 16.2 0.0034 17.2 11.2 2.3 1 1 0 1 1 1 1 bZIP transcription factor L1R_F9L PF02442.12 CEP20174.1 - 0.0063 16.0 0.3 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 Lipid membrane protein of large eukaryotic DNA viruses GAS PF13851.1 CEP20174.1 - 0.009 15.2 5.8 0.019 14.1 4.0 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.10 CEP20174.1 - 0.014 15.1 20.5 0.014 15.1 14.2 2.7 2 1 0 2 2 2 0 Basic region leucine zipper APG6 PF04111.7 CEP20174.1 - 0.031 13.3 2.1 0.054 12.5 1.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PRCC PF10253.4 CEP20174.1 - 0.048 14.3 10.6 0.3 11.7 4.6 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting UPF0242 PF06785.6 CEP20174.1 - 0.082 11.5 2.2 0.13 10.9 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Atg14 PF10186.4 CEP20174.1 - 0.086 11.7 10.3 0.031 13.2 5.1 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3439 PF11921.3 CEP20174.1 - 0.11 12.2 10.2 0.22 11.2 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CEP20174.1 - 0.16 9.6 10.9 0.026 12.3 5.0 1.5 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 CEP20174.1 - 0.24 9.3 12.7 0.32 8.9 8.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 V_ATPase_I PF01496.14 CEP20174.1 - 0.33 8.7 2.8 0.46 8.2 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3552 PF12072.3 CEP20174.1 - 0.45 9.6 8.3 0.87 8.7 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Mnd1 PF03962.10 CEP20174.1 - 1.7 8.2 7.7 0.33 10.5 2.8 1.7 2 0 0 2 2 2 0 Mnd1 family Striatin PF08232.7 CEP20174.1 - 1.9 8.7 8.8 0.72 10.1 3.8 2.0 1 1 1 2 2 2 0 Striatin family IncA PF04156.9 CEP20174.1 - 5.1 6.6 9.0 0.26 10.8 2.6 1.5 2 0 0 2 2 2 0 IncA protein AAA_33 PF13671.1 CEP20175.1 - 2.1e-17 63.3 0.1 3.6e-17 62.5 0.0 1.4 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 CEP20175.1 - 0.00057 19.1 0.0 0.00057 19.1 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 RVT_1 PF00078.22 CEP20176.1 - 2.2e-30 105.5 1.2 2.5e-22 79.2 0.1 3.5 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEP20177.1 - 2.2e-19 69.2 13.4 1.1e-13 50.8 0.2 3.3 3 1 0 3 3 3 2 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEP20177.1 - 7.2e-05 22.8 1.4 0.0002 21.3 0.1 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family MsyB PF13984.1 CEP20177.1 - 0.0034 17.4 0.5 4.1 7.4 0.0 2.7 2 0 0 2 2 2 2 MsyB protein HHH_2 PF12826.2 CEP20177.1 - 0.021 14.7 0.9 9.8 6.1 0.1 3.0 2 2 1 3 3 3 0 Helix-hairpin-helix motif VirK PF06903.7 CEP20177.1 - 0.032 13.9 0.3 11 5.8 0.0 2.6 2 0 0 2 2 2 0 VirK protein Swi5 PF07061.6 CEP20177.1 - 0.43 10.3 7.3 0.35 10.6 0.1 2.9 3 1 0 3 3 3 0 Swi5 Peptidase_M16_C PF05193.16 CEP20178.1 - 0.51 9.9 3.3 0.6 9.7 2.3 1.3 1 0 0 1 1 1 0 Peptidase M16 inactive domain PAT1 PF09770.4 CEP20178.1 - 1.2 7.3 31.2 1.3 7.1 21.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CEP20178.1 - 1.2 8.4 22.0 1.4 8.2 15.2 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 CEP20178.1 - 2.4 7.8 10.9 3.3 7.3 7.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RVT_1 PF00078.22 CEP20179.1 - 5.5e-21 74.9 0.0 1.2e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aldo_ket_red PF00248.16 CEP20181.1 - 0.019 13.7 0.1 0.67 8.7 0.1 2.0 1 1 1 2 2 2 0 Aldo/keto reductase family DUF4417 PF14386.1 CEP20181.1 - 0.021 14.1 0.2 0.039 13.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4417) Presenilin PF01080.12 CEP20182.1 - 6.6 5.4 6.4 9.3 4.9 4.4 1.1 1 0 0 1 1 1 0 Presenilin DUF3808 PF10300.4 CEP20184.1 - 2.7e-86 290.0 12.1 2.3e-59 201.2 1.8 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_12 PF13424.1 CEP20184.1 - 0.05 13.5 6.3 2 8.3 0.0 4.7 4 1 0 5 5 5 0 Tetratricopeptide repeat Phage_Mu_F PF04233.9 CEP20184.1 - 0.068 13.7 3.5 3.7 8.0 2.0 2.7 2 0 0 2 2 2 0 Phage Mu protein F like protein Sel1 PF08238.7 CEP20185.1 - 3e-09 37.1 1.6 0.0012 19.4 0.0 3.3 3 0 0 3 3 3 3 Sel1 repeat Cohesin_load PF10345.4 CEP20185.1 - 0.033 12.4 0.0 0.045 11.9 0.0 1.3 1 0 0 1 1 1 0 Cohesin loading factor Cobl PF09469.5 CEP20185.1 - 0.82 9.6 4.4 2.9 7.9 3.0 1.9 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Chorion_2 PF03964.10 CEP20185.1 - 2.1 8.9 18.1 3.6 8.1 8.0 3.2 2 1 1 3 3 3 0 Chorion family 2 Ctr PF04145.10 CEP20186.1 - 3.9 7.5 4.7 30 4.6 3.0 2.3 2 1 0 2 2 2 0 Ctr copper transporter family MS_channel PF00924.13 CEP20188.1 - 1.6e-20 73.3 0.5 2.5e-20 72.6 0.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CEP20188.1 - 3e-05 22.9 0.1 9.6e-05 21.4 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CEP20188.1 - 0.00025 21.1 2.5 0.0021 18.1 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CEP20188.1 - 0.00032 20.3 0.1 0.0011 18.7 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CEP20188.1 - 0.00081 18.6 0.2 0.0023 17.2 0.2 1.8 1 0 0 1 1 1 1 EF hand Colicin_im PF03857.8 CEP20188.1 - 0.31 10.7 3.3 0.096 12.4 0.2 1.7 2 0 0 2 2 2 0 Colicin immunity protein Homeobox PF00046.24 CEP20189.1 - 4.6e-18 64.5 2.1 4.6e-18 64.5 1.4 2.5 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CEP20189.1 - 0.0045 16.6 0.3 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain CH PF00307.26 CEP20191.1 - 7.4e-43 145.0 3.1 6.5e-22 77.6 0.0 3.4 4 1 1 5 5 5 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CEP20191.1 - 4.4e-12 45.4 0.2 1.5e-08 34.1 0.0 3.2 2 1 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.5 CEP20191.1 - 1.1e-10 41.2 0.3 3.2e-10 39.8 0.2 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Spectrin PF00435.16 CEP20191.1 - 0.0021 18.3 5.6 0.0045 17.2 0.4 2.8 2 1 0 2 2 2 1 Spectrin repeat DASH_Duo1 PF08651.5 CEP20191.1 - 0.011 15.2 1.7 0.06 12.9 0.8 2.4 1 1 1 2 2 2 0 DASH complex subunit Duo1 Apolipoprotein PF01442.13 CEP20191.1 - 0.016 14.7 1.6 0.032 13.7 1.1 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2935 PF11155.3 CEP20191.1 - 0.076 13.1 1.0 0.3 11.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.7 CEP20191.1 - 0.31 10.8 5.7 0.072 12.9 1.2 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 CEP20191.1 - 3.4 7.7 5.8 3.9 7.5 1.1 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family OrfB_Zn_ribbon PF07282.6 CEP20192.1 - 1.5e-09 37.3 13.0 1.8e-09 37.0 0.2 3.6 3 0 0 3 3 3 2 Putative transposase DNA-binding domain zf-CCHC PF00098.18 CEP20192.1 - 0.15 12.0 6.5 3.3 7.8 0.4 3.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 CEP20192.1 - 0.4 10.4 9.6 0.71 9.6 0.2 3.3 3 0 0 3 3 3 0 Zinc knuckle OrfB_Zn_ribbon PF07282.6 CEP20193.1 - 8.1e-10 38.2 0.1 8.1e-10 38.2 0.1 2.0 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Crystall PF00030.14 CEP20193.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin Arrestin_N PF00339.24 CEP20193.1 - 0.22 11.3 2.8 0.48 10.2 1.2 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain zf-DNL PF05180.7 CEP20193.1 - 0.26 11.0 2.4 0.48 10.1 0.6 2.2 2 0 0 2 2 2 0 DNL zinc finger Homeobox PF00046.24 CEP20194.1 - 0.036 13.6 0.1 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Homeobox domain Exo_endo_phos_2 PF14529.1 CEP20195.1 - 0.011 15.2 0.3 0.025 14.2 0.0 1.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RVT_1 PF00078.22 CEP20197.1 - 1.7e-22 79.8 0.0 2.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP20 PF00011.16 CEP20198.1 - 2.6e-17 62.5 0.1 7.7e-11 41.7 0.0 2.3 1 1 0 2 2 2 2 Hsp20/alpha crystallin family GOLGA2L5 PF15070.1 CEP20198.1 - 0.057 11.9 0.1 0.074 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 tRNA_synt_1c_R2 PF04557.10 CEP20198.1 - 1.7 9.4 4.4 5.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Abhydrolase_6 PF12697.2 CEP20199.1 - 8.8e-14 51.9 1.4 2.4e-13 50.5 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family DSPc PF00782.15 CEP20199.1 - 8.9e-11 41.5 0.0 8.9e-11 41.5 0.0 4.6 5 1 1 6 6 6 1 Dual specificity phosphatase, catalytic domain Abhydrolase_5 PF12695.2 CEP20199.1 - 5.6e-07 29.4 0.3 8.6e-06 25.5 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEP20199.1 - 7.9e-07 28.8 0.0 2.5e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CEP20199.1 - 7e-05 22.4 0.0 7e-05 22.4 0.0 2.7 3 0 0 3 3 3 1 Serine hydrolase Y_phosphatase PF00102.22 CEP20199.1 - 0.0014 17.9 0.6 0.0044 16.3 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CEP20199.1 - 0.0083 16.1 0.0 0.0083 16.1 0.0 4.9 2 1 0 3 3 3 1 Inositol hexakisphosphate LRR_8 PF13855.1 CEP20199.1 - 0.034 13.9 1.7 0.059 13.1 0.4 2.0 2 0 0 2 2 2 0 Leucine rich repeat Lipase_3 PF01764.20 CEP20199.1 - 0.065 12.8 0.1 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) TBPIP PF07106.8 CEP20200.1 - 4.9e-38 130.3 10.0 6e-38 130.0 6.9 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.11 CEP20200.1 - 0.00019 21.4 0.2 0.0031 17.5 0.3 2.4 2 1 0 2 2 2 1 Penicillinase repressor PilJ PF13675.1 CEP20200.1 - 0.00086 19.6 3.0 0.12 12.7 0.2 2.4 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3702 PF12486.3 CEP20200.1 - 0.0019 17.9 2.8 0.0025 17.4 1.2 1.7 1 1 0 1 1 1 1 ImpA domain protein DUF972 PF06156.8 CEP20200.1 - 0.006 16.9 8.9 0.074 13.4 5.9 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF972) RraB PF06877.6 CEP20200.1 - 0.0098 16.5 0.3 0.021 15.4 0.2 1.5 1 0 0 1 1 1 1 Regulator of ribonuclease activity B APG6 PF04111.7 CEP20200.1 - 0.011 14.8 6.9 0.016 14.2 4.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2730 PF10805.3 CEP20200.1 - 0.013 15.2 5.1 0.11 12.2 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF4201 PF13870.1 CEP20200.1 - 0.014 14.7 5.0 0.028 13.8 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) YABBY PF04690.8 CEP20200.1 - 0.02 15.1 0.9 0.031 14.5 0.6 1.4 1 0 0 1 1 1 0 YABBY protein KIAA1430 PF13879.1 CEP20200.1 - 0.021 15.2 3.5 0.055 13.8 2.4 1.7 1 0 0 1 1 1 0 KIAA1430 homologue Ax_dynein_light PF10211.4 CEP20200.1 - 0.027 14.3 7.3 0.053 13.3 5.1 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain DUF904 PF06005.7 CEP20200.1 - 0.03 14.5 12.8 5.6 7.3 10.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 CEP20200.1 - 0.031 14.2 12.0 0.034 14.0 2.4 2.7 1 1 1 2 2 2 0 bZIP transcription factor IncA PF04156.9 CEP20200.1 - 0.037 13.6 13.3 0.054 13.0 9.2 1.5 1 1 0 1 1 1 0 IncA protein DUF3106 PF11304.3 CEP20200.1 - 0.044 14.1 4.1 0.2 12.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Mnd1 PF03962.10 CEP20200.1 - 0.049 13.2 9.6 0.088 12.4 6.6 1.5 1 1 0 1 1 1 0 Mnd1 family BMFP PF04380.8 CEP20200.1 - 0.054 13.6 5.1 6.2 7.0 0.7 3.1 3 0 0 3 3 3 0 Membrane fusogenic activity HAUS6_N PF14661.1 CEP20200.1 - 0.065 12.5 4.3 0.085 12.2 3.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.10 CEP20200.1 - 0.071 12.6 11.9 0.55 9.7 2.5 2.5 1 1 1 2 2 2 0 Septum formation initiator RE_AlwI PF09491.5 CEP20200.1 - 0.085 11.3 9.4 0.1 11.0 6.5 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease V_ATPase_I PF01496.14 CEP20200.1 - 0.093 10.5 5.5 0.1 10.4 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CEP20200.1 - 0.1 11.0 9.0 0.15 10.4 6.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF812 PF05667.6 CEP20200.1 - 0.12 10.8 9.8 0.15 10.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_2 PF07716.10 CEP20200.1 - 0.27 11.1 9.4 2.1 8.2 0.7 2.9 2 0 0 2 2 2 0 Basic region leucine zipper DUF948 PF06103.6 CEP20200.1 - 0.41 10.5 5.6 40 4.1 3.8 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Allexi_40kDa PF05549.6 CEP20200.1 - 0.48 9.6 3.7 0.66 9.2 2.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4140 PF13600.1 CEP20200.1 - 0.59 10.6 9.5 0.27 11.6 1.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2894 PF11445.3 CEP20200.1 - 0.91 9.7 7.4 2.4 8.4 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) Nnf1 PF03980.9 CEP20200.1 - 0.99 9.4 12.8 3.2 7.7 1.2 2.8 1 1 1 2 2 2 0 Nnf1 TSC22 PF01166.13 CEP20200.1 - 1.1 9.3 8.8 1.4 8.8 3.8 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family Mto2_bdg PF12808.2 CEP20200.1 - 1.1 9.4 9.5 4.5 7.4 2.1 2.8 2 1 1 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Herpes_BLRF2 PF05812.7 CEP20200.1 - 1.4 8.7 11.0 3.7 7.3 3.8 2.8 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein Spc24 PF08286.6 CEP20200.1 - 2.7 7.7 10.0 2.1 8.0 4.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PCRF PF03462.13 CEP20200.1 - 6.5 6.4 7.9 4.9 6.8 0.4 2.5 1 1 1 2 2 2 0 PCRF domain HALZ PF02183.13 CEP20200.1 - 6.6 6.5 9.2 1.6 8.5 1.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2203 PF09969.4 CEP20200.1 - 6.7 6.9 7.0 8.2 6.6 3.0 2.2 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4337 PF14235.1 CEP20200.1 - 7 6.4 9.0 0.83 9.4 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Occludin_ELL PF07303.8 CEP20200.1 - 8.7 7.1 10.0 1.5 9.6 3.1 2.4 2 1 0 2 2 2 0 Occludin homology domain DivIVA PF05103.8 CEP20200.1 - 9.3 6.3 13.0 14 5.7 8.3 2.1 1 1 0 1 1 1 0 DivIVA protein DUF2813 PF11398.3 CEP20201.1 - 0.071 12.1 0.1 0.078 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Complex1_LYR PF05347.10 CEP20201.1 - 0.079 12.7 0.1 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Ofd1_CTDD PF10637.4 CEP20202.1 - 6.5e-81 271.3 0.0 1.6e-73 247.1 0.0 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CEP20202.1 - 4.4e-16 59.2 0.0 1.4e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RVT_1 PF00078.22 CEP20204.1 - 6e-22 78.0 0.0 1.4e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CEP20204.1 - 4e-09 36.7 0.0 7.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CEP20204.1 - 6.2e-08 32.2 0.2 1.4e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SBP_bac_8 PF13416.1 CEP20205.1 - 0.12 12.1 1.7 0.15 11.7 0.5 1.6 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein DDE_3 PF13358.1 CEP20206.1 - 1.3e-29 102.7 0.0 2.4e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease