# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Glyco_transf_25 PF01755.17 OAF98457.1 - 3.8e-11 43.2 0.0 1.9e-10 41.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) RIIa PF02197.17 OAF98457.1 - 0.14 11.8 0.1 24 4.7 0.0 2.5 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit zf-LITAF-like PF10601.9 OAF98458.1 - 0.76 10.1 3.7 0.27 11.5 0.5 2.0 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain APH PF01636.23 OAF98460.1 - 3.7e-10 40.1 0.1 8.7e-10 38.9 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAF98460.1 - 6.5e-06 25.9 0.0 2.5e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase SIR2 PF02146.17 OAF98462.1 - 1.4e-33 116.3 0.0 1.9e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF4939 PF16297.5 OAF98465.1 - 1.8e-05 24.6 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) SlyX PF04102.12 OAF98465.1 - 0.037 14.7 0.8 0.075 13.7 0.8 1.5 1 0 0 1 1 1 0 SlyX DUF294 PF03445.13 OAF98465.1 - 0.1 12.4 0.6 0.98 9.2 0.0 2.0 2 0 0 2 2 2 0 Putative nucleotidyltransferase DUF294 DEAD PF00270.29 OAF98468.1 - 0.00012 21.9 0.1 0.00012 21.9 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase p450 PF00067.22 OAF98470.1 - 2.9e-64 217.5 0.0 4.7e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NMT_C PF02799.15 OAF98470.1 - 0.041 13.4 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain adh_short_C2 PF13561.6 OAF98471.1 - 2.3e-53 181.2 2.7 6.7e-53 179.7 2.7 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAF98471.1 - 9.9e-44 149.1 1.4 1.3e-43 148.7 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAF98471.1 - 6.6e-09 35.9 0.1 1.2e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAF98471.1 - 0.00013 21.2 0.0 0.0003 20.0 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAF98471.1 - 0.00045 19.8 0.2 0.00086 18.8 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family BTB PF00651.31 OAF98472.1 - 6.9e-12 45.6 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4722 PF15849.5 OAF98473.1 - 0.17 11.6 0.6 0.69 9.6 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4722) zf-C2H2_4 PF13894.6 OAF98474.1 - 1.4e-11 44.2 28.2 0.019 15.7 1.3 6.0 6 1 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OAF98474.1 - 4e-10 39.6 31.8 0.054 14.0 3.5 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAF98474.1 - 3.1e-07 30.7 10.7 0.99 9.8 0.1 4.5 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OAF98474.1 - 2.5e-06 27.7 15.1 0.013 15.9 0.0 5.0 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAF98474.1 - 0.0025 18.0 16.2 0.059 13.7 0.0 4.9 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 OAF98474.1 - 0.011 15.3 0.0 0.011 15.3 0.0 4.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 OAF98474.1 - 0.018 15.1 15.2 1.9 8.6 5.6 4.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_9 PF16293.5 OAF98474.1 - 0.087 12.7 8.8 0.18 11.6 0.0 4.2 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) Ser_hydrolase PF06821.13 OAF98474.1 - 0.1 12.4 0.0 2.1 8.2 0.1 2.0 2 0 0 2 2 2 0 Serine hydrolase zf-C2H2_6 PF13912.6 OAF98474.1 - 0.31 11.1 0.2 0.31 11.1 0.2 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger zf-Di19 PF05605.12 OAF98474.1 - 0.33 11.3 0.2 0.33 11.3 0.2 4.3 2 1 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 OAF98474.1 - 2.2 8.5 20.3 0.75 10.0 0.3 4.5 3 2 2 5 5 5 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 OAF98474.1 - 7.2 6.7 16.9 2.5e+02 1.7 2.0 4.6 2 1 1 3 3 3 0 zinc-ribbons zf-B_box PF00643.24 OAF98475.1 - 0.028 14.6 5.3 0.053 13.7 5.3 1.4 1 0 0 1 1 1 0 B-box zinc finger IBR PF01485.21 OAF98475.1 - 0.078 13.2 4.3 0.15 12.3 4.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain baeRF_family12 PF18856.1 OAF98475.1 - 0.089 13.4 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 C1_2 PF03107.16 OAF98475.1 - 0.1 13.0 3.3 0.18 12.2 3.3 1.4 1 0 0 1 1 1 0 C1 domain WD40 PF00400.32 OAF98476.1 - 2.4e-13 50.3 0.2 1.7e-11 44.4 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAF98476.1 - 3.5e-05 22.9 0.6 0.00016 20.7 0.2 2.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OAF98476.1 - 0.00021 21.5 0.0 0.00033 20.9 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAF98476.1 - 0.004 17.0 1.4 1.6 8.8 0.1 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OAF98476.1 - 0.0041 15.8 0.0 0.0051 15.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Pkinase_Tyr PF07714.17 OAF98477.1 - 3.2e-12 46.3 0.0 5.8e-12 45.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAF98477.1 - 6.9e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pap_E4 PF02711.14 OAF98478.1 - 0.99 10.4 5.7 1.7 9.7 5.7 1.4 1 0 0 1 1 1 0 E4 protein VSP PF03302.13 OAF98479.1 - 0.00095 18.1 4.6 0.0023 16.9 0.7 2.3 1 1 1 2 2 2 2 Giardia variant-specific surface protein LysM PF01476.20 OAF98479.1 - 0.0025 17.8 0.0 28 4.9 0.0 3.7 4 0 0 4 4 4 3 LysM domain LysM PF01476.20 OAF98481.1 - 0.011 15.7 0.0 0.035 14.2 0.0 1.9 2 0 0 2 2 2 0 LysM domain Glyco_hydro_18 PF00704.28 OAF98482.1 - 1.1e-59 202.7 0.0 1.8e-59 202.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MqsR_toxin PF15723.5 OAF98483.1 - 0.088 13.2 1.3 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA YabA PF06156.13 OAF98483.1 - 0.42 11.3 0.1 0.42 11.3 0.1 3.2 3 0 0 3 3 3 0 Initiation control protein YabA Acyl-CoA_dh_M PF02770.19 OAF98484.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain CDC45 PF02724.14 OAF98484.1 - 1.4 7.1 8.2 2.2 6.5 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Rhomboid_N PF12122.8 OAF98487.1 - 0.058 13.6 0.0 0.064 13.4 0.0 1.0 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease Ank_2 PF12796.7 OAF98488.1 - 6e-47 158.1 0.0 1.7e-14 54.2 0.1 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAF98488.1 - 4.4e-33 113.2 0.2 9.8e-09 35.6 0.0 5.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAF98488.1 - 1.4e-31 104.9 0.0 0.0034 17.8 0.0 9.1 8 1 1 9 9 9 7 Ankyrin repeat Ank PF00023.30 OAF98488.1 - 1.2e-30 104.6 0.0 0.00027 21.3 0.0 7.9 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OAF98488.1 - 2.6e-28 97.7 0.1 6.6e-07 29.5 0.0 6.1 4 2 3 7 7 7 5 Ankyrin repeats (many copies) CorA PF01544.18 OAF98488.1 - 8.4e-11 41.7 0.1 1.2e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Toxin_trans PF07952.12 OAF98488.1 - 0.021 13.9 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain HTH_18 PF12833.7 OAF98488.1 - 0.046 14.0 0.0 0.21 11.9 0.0 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain ApoO PF09769.9 OAF98488.1 - 0.051 13.5 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O DDE_3 PF13358.6 OAF98489.1 - 8.8e-07 28.8 1.1 1.5e-06 28.1 0.6 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease GYF_2 PF14237.6 OAF98490.1 - 0.12 12.2 0.1 0.73 9.7 0.0 2.3 3 0 0 3 3 3 0 GYF domain 2 GST_N PF02798.20 OAF98493.1 - 2.9e-13 50.0 0.1 7.1e-12 45.5 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAF98493.1 - 5.5e-12 45.9 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAF98493.1 - 3.3e-09 36.8 0.0 6.5e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAF98493.1 - 1.3e-07 31.9 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAF98493.1 - 7.2e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OAF98493.1 - 0.057 13.7 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Cluap1 PF10234.9 OAF98493.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Methyltransf_2 PF00891.18 OAF98494.1 - 3.3e-15 56.0 0.0 3.6e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAF98494.1 - 0.014 16.1 0.0 0.017 15.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 OAF98494.1 - 0.047 13.2 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 OAF98494.1 - 0.076 13.0 0.1 0.096 12.7 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain UDPGT PF00201.18 OAF98495.1 - 1.4e-10 40.6 0.0 2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAF98495.1 - 0.0015 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ArAE_2_N PF10337.9 OAF98496.1 - 1.1e-16 61.0 0.0 1.1e-16 61.0 0.0 3.0 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAF98496.1 - 3.6e-13 49.7 17.3 3.6e-13 49.7 17.3 2.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAF98496.1 - 7e-08 32.6 0.1 3e-05 24.0 0.1 3.0 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 DUF4939 PF16297.5 OAF98498.1 - 0.0064 16.3 0.0 0.0072 16.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) F-box PF00646.33 OAF98499.1 - 1.6e-06 27.8 0.2 1e-05 25.3 0.2 2.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAF98499.1 - 6.5e-06 25.9 0.2 2.2e-05 24.2 0.2 2.0 1 0 0 1 1 1 1 F-box-like Spc7_N PF15402.6 OAF98501.1 - 0.081 11.2 12.9 0.1 10.9 12.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Dicty_REP PF05086.12 OAF98501.1 - 1 7.3 4.2 1.2 7.1 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NUT PF12881.7 OAF98501.1 - 4 5.8 14.0 5.6 5.3 14.0 1.1 1 0 0 1 1 1 0 NUT protein Zn_clus PF00172.18 OAF98502.1 - 3.5e-08 33.4 8.0 3.5e-08 33.4 8.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAF98502.1 - 9.4e-08 31.4 0.9 1.3e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain HTH_Tnp_Tc5 PF03221.16 OAF98503.1 - 1.3e-06 28.3 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain ATPgrasp_N PF18130.1 OAF98504.1 - 7.7e-14 52.0 0.0 2.3e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 OAF98504.1 - 1.1e-11 44.6 0.0 2.8e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAF98504.1 - 1.6e-07 31.0 0.0 3.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 OAF98504.1 - 0.00037 20.6 0.0 0.00092 19.3 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 OAF98504.1 - 0.0027 17.5 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 OAF98504.1 - 0.014 15.1 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 OAF98504.1 - 0.075 12.5 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PTR2 PF00854.21 OAF98505.1 - 9e-69 232.2 0.0 1.7e-68 231.3 0.0 1.4 1 1 0 1 1 1 1 POT family PMT PF02366.18 OAF98505.1 - 0.0024 17.5 0.3 0.032 13.8 0.0 2.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase HET PF06985.11 OAF98506.1 - 9.1e-36 123.4 1.0 2.1e-35 122.2 1.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) T2SSM_b PF10741.9 OAF98506.1 - 0.16 11.8 0.1 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF1507 PF07408.11 OAF98508.1 - 0.014 15.2 1.7 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1507) ABC_tran_CTD PF16326.5 OAF98508.1 - 0.078 13.2 1.1 0.16 12.2 1.1 1.5 1 1 0 1 1 1 0 ABC transporter C-terminal domain Receptor_IA-2 PF11548.8 OAF98508.1 - 0.13 12.3 0.1 1.7 8.7 0.0 2.1 1 1 1 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 FHA PF00498.26 OAF98510.1 - 4.6e-05 23.7 0.0 0.001 19.3 0.0 2.0 2 0 0 2 2 2 1 FHA domain SET PF00856.28 OAF98511.1 - 3e-15 57.0 0.1 1.1e-14 55.2 0.1 1.9 1 1 0 1 1 1 1 SET domain SAF PF08666.12 OAF98511.1 - 0.081 13.6 0.0 11 6.7 0.0 2.4 2 0 0 2 2 2 0 SAF domain DivIC PF04977.15 OAF98515.1 - 0.65 9.8 3.9 10 6.0 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator SNF2_N PF00176.23 OAF98519.1 - 0.00057 18.7 0.0 0.0006 18.6 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 OAF98519.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EF-1_beta_acid PF10587.9 OAF98523.1 - 0.2 12.1 2.8 0.52 10.8 2.8 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DHR10 PF18595.1 OAF98528.1 - 0.0091 16.0 14.9 0.076 13.1 2.3 2.7 2 0 0 2 2 2 2 Designed helical repeat protein 10 domain Na_Ca_ex_C PF16494.5 OAF98528.1 - 0.011 16.2 0.7 0.036 14.5 0.1 2.2 3 0 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain Snapin_Pallidin PF14712.6 OAF98528.1 - 0.34 11.4 5.9 14 6.2 0.7 3.5 3 0 0 3 3 3 0 Snapin/Pallidin DUF3450 PF11932.8 OAF98528.1 - 1.1 8.5 9.0 2.5 7.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TPR_2 PF07719.17 OAF98528.1 - 1.2 9.5 2.8 10 6.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat GrpE PF01025.19 OAF98528.1 - 1.3 8.7 7.1 2.8 7.6 7.1 1.6 1 0 0 1 1 1 0 GrpE DegS PF05384.11 OAF98528.1 - 1.4 8.4 6.6 9.2 5.7 6.5 2.3 1 1 0 1 1 1 0 Sensor protein DegS CC2-LZ PF16516.5 OAF98528.1 - 1.6 9.2 9.0 0.79 10.1 3.6 2.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Stig1 PF04885.13 OAF98530.1 - 0.029 14.9 3.3 0.049 14.1 3.3 1.3 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF3400 PF11880.8 OAF98531.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) Abhydrolase_1 PF00561.20 OAF98532.1 - 1e-17 64.6 0.0 4.2e-16 59.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAF98532.1 - 7.3e-14 52.9 1.2 9e-14 52.6 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAF98532.1 - 2.1e-12 46.8 0.2 1e-11 44.6 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 OAF98532.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase zf-MYND PF01753.18 OAF98535.1 - 6.4e-06 26.1 11.7 1.4e-05 25.0 11.7 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OAF98535.1 - 0.38 10.9 4.8 0.85 9.8 4.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ACBP PF00887.19 OAF98536.1 - 1.5e-23 82.8 0.6 2.8e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein HR1 PF02185.16 OAF98536.1 - 0.071 13.2 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Hr1 repeat FAD_binding_4 PF01565.23 OAF98537.1 - 0.00011 22.0 0.1 0.0002 21.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BNR PF02012.20 OAF98538.1 - 0.017 15.0 0.2 0.062 13.3 0.2 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat AMP-binding PF00501.28 OAF98539.1 - 4e-51 174.0 0.0 5.8e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 OAF98539.1 - 9.2e-25 88.1 0.1 4.7e-24 85.8 0.1 2.2 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 OAF98539.1 - 1.1e-05 25.6 0.3 3.1e-05 24.2 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 OAF98539.1 - 0.047 13.3 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAF98539.1 - 0.14 12.8 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family bPH_6 PF10756.9 OAF98539.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain DUF565 PF04483.12 OAF98540.1 - 0.073 13.6 0.5 0.24 12.0 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF565) CD47 PF04549.14 OAF98540.1 - 0.093 12.9 0.5 0.093 12.9 0.5 2.0 2 0 0 2 2 2 0 CD47 transmembrane region FMO-like PF00743.19 OAF98541.1 - 1.9e-10 39.8 0.1 2.1e-08 33.1 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAF98541.1 - 1.3e-09 37.7 0.0 7.7e-07 28.6 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAF98541.1 - 7.6e-08 31.9 0.0 4.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAF98541.1 - 0.00025 21.2 0.1 0.0019 18.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAF98541.1 - 0.00099 19.2 0.0 0.023 14.7 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAF98541.1 - 0.0016 18.5 0.1 0.49 10.4 0.0 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAF98541.1 - 0.0072 16.9 0.1 0.068 13.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAF98541.1 - 0.014 14.6 1.3 1.1 8.4 0.2 2.6 2 1 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAF98541.1 - 0.015 14.6 0.9 0.25 10.6 0.0 3.0 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAF98541.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAF98541.1 - 0.025 15.0 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2749 PF10907.8 OAF98541.1 - 0.12 12.5 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Zn_clus PF00172.18 OAF98542.1 - 9.4e-09 35.3 7.7 1.6e-08 34.5 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAF98542.1 - 1.1e-05 24.4 2.6 1.1e-05 24.4 2.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tannase PF07519.11 OAF98543.1 - 4.6e-113 378.6 0.1 5.9e-113 378.3 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase SpoU_methylas_C PF12105.8 OAF98543.1 - 0.0054 16.4 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 SpoU, rRNA methylase, C-terminal Peptidase_S9 PF00326.21 OAF98543.1 - 0.012 15.0 0.2 0.15 11.5 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAF98543.1 - 0.02 14.5 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAF98543.1 - 0.053 12.8 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PAZ PF02170.22 OAF98543.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 PAZ domain RTA1 PF04479.13 OAF98544.1 - 1.6e-56 191.2 13.7 2.3e-56 190.7 13.7 1.2 1 0 0 1 1 1 1 RTA1 like protein ECH_1 PF00378.20 OAF98545.1 - 0.0003 20.2 0.0 0.00036 19.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAF98545.1 - 0.0015 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 OAF98546.1 - 1.4e-19 70.5 0.0 2.4e-19 69.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF98546.1 - 1.2e-05 24.8 0.0 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAF98546.1 - 4.1e-05 23.0 0.0 7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAF98546.1 - 0.16 11.9 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family MIF4G_like_2 PF09090.11 OAF98548.1 - 0.0065 16.0 0.9 0.2 11.1 1.1 2.1 1 1 1 2 2 2 1 MIF4G like T6SS_VasE PF05936.12 OAF98548.1 - 0.045 12.5 3.7 0.081 11.6 1.1 1.9 2 0 0 2 2 2 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE COG2 PF06148.11 OAF98548.1 - 0.14 12.2 2.0 0.4 10.8 0.0 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HET PF06985.11 OAF98552.1 - 2.6e-39 134.9 3.4 4.7e-39 134.1 3.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 OAF98552.1 - 9.7e-09 35.7 1.1 0.00031 21.3 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAF98552.1 - 0.0024 18.2 1.9 1.7e+02 3.3 0.0 6.4 7 0 0 7 7 7 0 Ankyrin repeat LPD3 PF18798.1 OAF98553.1 - 0.042 14.1 0.4 0.081 13.2 0.1 1.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 3 PCRF PF03462.18 OAF98553.1 - 0.16 11.8 6.3 0.21 11.5 6.3 1.1 1 0 0 1 1 1 0 PCRF domain Bud13 PF09736.9 OAF98553.1 - 1.9 8.9 11.2 2.5 8.5 11.2 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex BTB PF00651.31 OAF98554.1 - 2.1e-06 28.0 0.1 3.2e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3306 PF11748.8 OAF98557.1 - 0.057 14.3 3.7 0.081 13.8 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) BCS1_N PF08740.11 OAF98560.1 - 2.6e-35 122.1 0.4 4.5e-35 121.3 0.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAF98560.1 - 1.4e-16 61.1 0.0 4.4e-15 56.3 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAF98560.1 - 0.0027 17.7 0.0 0.0079 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAF98560.1 - 0.0062 16.9 0.0 0.024 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OAF98560.1 - 0.0096 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 OAF98560.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 OAF98560.1 - 0.04 14.1 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_assoc PF14363.6 OAF98560.1 - 0.056 13.8 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Polyoma_lg_T_C PF06431.11 OAF98560.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_18 PF13238.6 OAF98560.1 - 0.076 13.6 0.2 0.48 11.0 0.0 2.5 4 0 0 4 4 3 0 AAA domain AAA_11 PF13086.6 OAF98560.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 OAF98560.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 OAF98560.1 - 0.18 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Acetyltransf_3 PF13302.7 OAF98561.1 - 7e-16 59.2 3.0 6.2e-15 56.1 3.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAF98561.1 - 4.5e-05 23.7 0.0 6.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OAF98561.1 - 6.4e-05 22.7 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAF98561.1 - 0.017 15.1 0.2 0.03 14.3 0.2 1.3 1 0 0 1 1 1 0 FR47-like protein Abhydrolase_6 PF12697.7 OAF98562.1 - 0.0005 20.7 0.8 0.00054 20.6 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OAF98562.1 - 0.00062 19.5 0.1 0.00087 19.0 0.1 1.1 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 OAF98562.1 - 0.00096 19.3 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 OAF98562.1 - 0.00096 18.5 0.3 0.0015 17.8 0.2 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAF98562.1 - 0.0013 18.4 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OAF98562.1 - 0.002 18.0 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 OAF98562.1 - 0.019 14.0 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 Chlorophyllase Ser_hydrolase PF06821.13 OAF98562.1 - 0.021 14.7 0.2 0.029 14.2 0.2 1.3 1 1 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 OAF98562.1 - 0.052 12.4 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF3530 PF12048.8 OAF98562.1 - 0.076 12.4 0.1 0.087 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) FA PF08736.11 OAF98563.1 - 0.13 12.4 1.3 0.43 10.7 1.3 2.0 1 0 0 1 1 1 0 FERM adjacent (FA) Ank_2 PF12796.7 OAF98565.1 - 9.1e-09 35.8 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAF98565.1 - 2.9e-06 27.7 0.1 0.00059 20.4 0.0 2.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAF98565.1 - 0.00018 21.7 0.0 0.012 16.1 0.0 3.4 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OAF98565.1 - 0.00034 20.9 0.3 0.01 16.2 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat HXXSHH PF07586.11 OAF98565.1 - 0.11 12.0 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) KorB PF08535.10 OAF98565.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 KorB domain RNA_POL_M_15KD PF02150.16 OAF98565.1 - 2.1 8.3 6.6 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Ank_2 PF12796.7 OAF98566.1 - 1.3e-06 28.9 0.1 3.8e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_22 PF13401.6 OAF98566.1 - 2.9e-06 27.6 0.0 1.5e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ank PF00023.30 OAF98566.1 - 2e-05 24.8 0.8 0.17 12.4 0.3 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OAF98566.1 - 4.2e-05 23.6 0.3 0.0057 17.1 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat NACHT PF05729.12 OAF98566.1 - 0.00012 22.0 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 OAF98566.1 - 0.00081 19.6 0.6 0.029 14.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ATPase PF06745.13 OAF98566.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Ank_4 PF13637.6 OAF98566.1 - 0.063 13.9 0.2 3.2 8.4 0.1 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) MARVEL PF01284.23 OAF98567.1 - 0.17 11.9 19.9 2.6 8.0 15.5 2.4 2 1 0 2 2 2 0 Membrane-associating domain VIT1 PF01988.19 OAF98567.1 - 0.52 10.1 5.8 0.87 9.4 5.8 1.6 1 1 0 1 1 1 0 VIT family DUF1361 PF07099.11 OAF98567.1 - 0.89 9.5 4.6 0.58 10.1 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1361) DUF4231 PF14015.6 OAF98567.1 - 1.5 9.3 5.2 3.4 8.2 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) AMP-binding PF00501.28 OAF98568.1 - 2.8e-67 227.2 0.0 6.1e-67 226.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAF98568.1 - 1.3e-09 38.8 0.0 2.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Arrestin_N PF00339.29 OAF98569.1 - 3e-10 40.3 0.1 2.9e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OAF98569.1 - 0.0023 18.4 0.1 0.017 15.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 OAF98569.1 - 0.029 13.6 0.1 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Rgp1 Bul1_C PF04426.12 OAF98569.1 - 0.036 13.5 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Bul1 C terminus PyrI_C PF02748.15 OAF98569.1 - 0.14 12.1 0.6 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Metal_resist PF13801.6 OAF98570.1 - 0.2 11.8 6.6 0.74 10.0 6.4 2.2 1 1 0 1 1 1 0 Heavy-metal resistance IHABP4_N PF16174.5 OAF98570.1 - 0.8 10.3 15.1 1.6 9.3 15.1 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Acetyltransf_7 PF13508.7 OAF98572.1 - 2e-10 41.0 0.0 2.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAF98572.1 - 3.3e-10 40.2 0.0 5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAF98572.1 - 7.8e-08 32.3 0.0 1.6e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAF98572.1 - 0.00047 20.2 0.3 0.0037 17.3 0.3 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAF98572.1 - 0.0007 19.7 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 OAF98572.1 - 0.00076 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAF98572.1 - 0.0052 17.5 0.1 0.0072 17.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain P2_Phage_GpR PF06891.11 OAF98572.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) OPT PF03169.15 OAF98573.1 - 1.2e-168 562.6 57.8 1.3e-168 562.4 57.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SoPB_HTH PF18090.1 OAF98574.1 - 0.1 12.7 0.2 2.3 8.4 0.0 2.4 1 1 2 3 3 3 0 Centromere-binding protein HTH domain SET PF00856.28 OAF98576.1 - 8.3e-14 52.3 0.6 8.3e-13 49.1 0.6 2.1 1 1 0 1 1 1 1 SET domain TPR_10 PF13374.6 OAF98576.1 - 0.00061 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat SAF PF08666.12 OAF98576.1 - 0.027 15.1 0.1 12 6.6 0.0 2.7 2 0 0 2 2 2 0 SAF domain FTCD_N PF07837.12 OAF98577.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain cwf21 PF08312.12 OAF98577.1 - 1.7 8.9 7.8 0.62 10.3 3.9 2.2 2 0 0 2 2 2 0 cwf21 domain MFS_1 PF07690.16 OAF98578.1 - 3.4e-32 111.7 23.8 4.2e-32 111.5 23.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily VIT1 PF01988.19 OAF98578.1 - 0.074 12.9 0.6 0.16 11.8 0.6 1.5 1 0 0 1 1 1 0 VIT family DJ-1_PfpI PF01965.24 OAF98579.1 - 2.1e-15 56.9 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GST_C_2 PF13410.6 OAF98580.1 - 2.6e-07 30.6 0.1 4.2e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAF98580.1 - 9.4e-07 29.0 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAF98580.1 - 4.6e-06 26.8 0.0 8.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAF98580.1 - 5.8e-06 26.6 0.1 2.1e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAF98580.1 - 0.0058 16.8 0.1 0.011 16.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAF98580.1 - 0.0084 16.7 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain pPIWI_RE_X PF13111.6 OAF98581.1 - 0.18 11.0 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain RNase_PH PF01138.21 OAF98582.1 - 0.053 14.0 0.1 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 Ribonucleas_3_3 PF14622.6 OAF98582.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAF98582.1 - 0.13 12.9 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease III domain UPRTase PF14681.6 OAF98584.1 - 1.6e-36 125.7 0.7 2.9e-36 124.9 0.7 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 OAF98584.1 - 1.8e-18 67.6 0.1 1.7e-16 61.2 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 OAF98584.1 - 1.7e-16 60.8 0.0 4.6e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.27 OAF98584.1 - 3.4e-05 23.4 0.1 0.00018 21.1 0.1 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 OAF98584.1 - 0.00043 19.8 0.6 0.049 13.1 0.1 2.8 3 0 0 3 3 3 1 Phosphoribosyl transferase KAP_NTPase PF07693.14 OAF98584.1 - 0.00064 19.1 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.6 OAF98584.1 - 0.002 18.3 0.1 0.0069 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAF98584.1 - 0.0032 17.9 0.6 0.021 15.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAF98584.1 - 0.0087 16.3 0.3 0.48 10.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 OAF98584.1 - 0.025 13.7 0.0 0.074 12.2 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 OAF98584.1 - 0.074 13.0 0.1 0.83 9.6 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 OAF98584.1 - 0.089 13.3 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAF98584.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea zf-3CxxC PF13695.6 OAF98585.1 - 2.1e-22 79.5 2.8 2.9e-22 79.0 2.8 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 OAF98585.1 - 0.78 10.5 9.2 3.4 8.5 4.4 2.7 2 1 0 2 2 2 0 Zinc-binding domain Syja_N PF02383.18 OAF98586.1 - 3.8e-08 33.0 0.0 4.8e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 SacI homology domain Ank_2 PF12796.7 OAF98587.1 - 1.5e-11 44.7 0.0 2.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAF98587.1 - 2.5e-10 40.7 0.1 2.8e-08 34.1 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAF98587.1 - 4.3e-09 36.5 0.0 1.5e-05 25.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAF98587.1 - 1.5e-07 31.1 0.0 0.0037 17.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OAF98587.1 - 1.3e-06 28.6 0.0 0.0031 17.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat HET PF06985.11 OAF98590.1 - 1.3e-19 71.0 4.8 4.1e-19 69.4 4.8 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PSK_trans_fac PF07704.11 OAF98590.1 - 0.058 14.2 0.3 0.058 14.2 0.3 3.0 3 0 0 3 3 3 0 Rv0623-like transcription factor PAF-AH_p_II PF03403.13 OAF98591.1 - 1.7e-16 59.8 0.0 1.7e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAF98591.1 - 2.9e-06 26.7 0.1 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAF98591.1 - 1e-05 24.6 0.0 2e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 OAF98591.1 - 8.4e-05 22.3 0.1 0.26 10.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAF98591.1 - 0.00011 22.9 0.2 0.00015 22.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OAF98591.1 - 0.0028 16.7 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase Peptidase_S9 PF00326.21 OAF98591.1 - 0.067 12.7 0.1 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 OAF98591.1 - 0.072 12.7 0.1 0.25 10.9 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Yip1 PF04893.17 OAF98592.1 - 0.068 12.9 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain PGF-CTERM PF18204.1 OAF98592.1 - 0.12 12.3 3.5 0.28 11.2 3.5 1.7 1 0 0 1 1 1 0 PGF-CTERM motif DUF2207 PF09972.9 OAF98592.1 - 0.3 9.8 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Aminotran_1_2 PF00155.21 OAF98594.1 - 1e-41 143.3 0.0 1.3e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 OAF98594.1 - 0.044 12.4 0.0 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-III WD40 PF00400.32 OAF98596.1 - 1.7e-10 41.3 0.1 2.9e-09 37.4 0.1 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAF98596.1 - 0.027 14.8 0.0 0.034 14.5 0.0 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 OAF98598.1 - 3.4e-57 193.9 0.0 3.8e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PKcGMP_CC PF16808.5 OAF98598.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Trp_DMAT PF11991.8 OAF98599.1 - 2.1e-101 340.0 0.1 2.4e-101 339.8 0.1 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.23 OAF98600.1 - 5.6e-24 84.5 3.2 8.4e-24 83.9 3.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAF98600.1 - 0.0024 17.9 0.2 0.0051 16.9 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_18 PF00704.28 OAF98601.1 - 4e-45 154.9 4.3 6.5e-45 154.2 4.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 OAF98601.1 - 4.5e-13 49.0 0.5 1.8e-06 27.9 0.1 2.9 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 OAF98601.1 - 0.00028 21.3 8.6 0.00028 21.3 8.6 4.0 4 1 0 4 4 4 1 Chitin recognition protein F-box-like PF12937.7 OAF98602.1 - 0.00096 19.0 0.1 0.0024 17.7 0.1 1.7 1 1 0 1 1 1 1 F-box-like Helo_like_N PF17111.5 OAF98603.1 - 1e-07 31.5 0.9 1.3e-07 31.2 0.9 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 OAF98603.1 - 8.1e-05 22.8 1.2 0.00017 21.7 1.2 1.6 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases SKA1 PF07160.12 OAF98603.1 - 0.031 14.1 0.2 0.041 13.7 0.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Spectrin PF00435.21 OAF98603.1 - 0.072 13.6 0.2 0.2 12.2 0.2 1.7 1 0 0 1 1 1 0 Spectrin repeat DUF3176 PF11374.8 OAF98604.1 - 7.1e-13 48.7 0.5 7.2e-13 48.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) GKAP PF03359.13 OAF98605.1 - 0.038 13.6 0.3 0.038 13.6 0.3 1.0 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein SRR1 PF07985.12 OAF98607.1 - 0.0032 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 SRR1 DEAD PF00270.29 OAF98608.1 - 4.3e-05 23.4 0.2 7.5e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Zn_clus PF00172.18 OAF98611.1 - 3.1e-09 36.8 12.8 5.1e-09 36.1 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAF98611.1 - 0.062 12.3 0.2 0.14 11.1 0.2 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain Copper-fist PF00649.18 OAF98612.1 - 4.2e-20 70.9 2.6 4.2e-20 70.9 2.6 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain zf-C2H2_2 PF12756.7 OAF98613.1 - 3.8e-31 107.4 14.5 7.7e-26 90.4 7.7 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OAF98613.1 - 1.6e-07 31.5 12.3 5.5e-07 29.8 2.8 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAF98613.1 - 1.2e-06 28.6 2.9 5.3e-06 26.6 2.2 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding SnoaL_2 PF12680.7 OAF98613.1 - 0.022 15.4 0.2 0.05 14.3 0.2 1.6 1 0 0 1 1 1 0 SnoaL-like domain HECT PF00632.25 OAF98614.1 - 2.7e-64 217.6 0.0 5.3e-64 216.6 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OAF98614.1 - 1.1e-20 73.6 4.9 4.1e-20 71.8 4.9 2.1 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A MFS_MOT1 PF16983.5 OAF98615.1 - 1.7e-55 186.2 33.9 1e-30 106.4 10.3 2.7 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily PAF-AH_p_II PF03403.13 OAF98617.1 - 3.1e-17 62.2 0.0 4.8e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAF98617.1 - 0.0017 17.4 0.2 0.0078 15.1 0.0 2.1 2 1 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 OAF98617.1 - 0.0029 17.3 0.0 0.64 9.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAF98617.1 - 0.013 14.8 0.1 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OAF98617.1 - 0.038 13.7 0.9 2.2 8.0 0.1 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OAF98617.1 - 0.19 10.7 0.1 19 4.1 0.0 2.4 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_6 PF12697.7 OAF98617.1 - 0.3 11.6 3.3 0.76 10.3 3.4 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.26 OAF98618.1 - 2.3e-26 92.3 0.1 9.1e-26 90.4 0.1 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAF98618.1 - 4.2e-21 76.4 0.0 1.9e-20 74.3 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAF98618.1 - 0.011 15.7 0.1 0.024 14.5 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAF98618.1 - 0.029 13.7 0.4 0.046 13.0 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 OAF98618.1 - 0.055 12.9 0.9 0.085 12.3 0.9 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Aa_trans PF01490.18 OAF98619.1 - 1.4e-51 175.5 36.5 1.6e-51 175.3 36.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tetraspanin PF00335.20 OAF98619.1 - 0.27 10.9 0.0 0.27 10.9 0.0 3.5 4 1 0 4 4 4 0 Tetraspanin family Sigma_reg_N PF13800.6 OAF98619.1 - 0.28 11.5 0.1 0.28 11.5 0.1 4.0 6 0 0 6 6 6 0 Sigma factor regulator N-terminal Cu-oxidase_3 PF07732.15 OAF98620.1 - 2.1e-38 131.0 1.4 4.5e-38 129.9 0.7 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAF98620.1 - 4.8e-30 104.1 6.4 1.1e-23 83.5 0.2 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OAF98620.1 - 2.6e-16 60.2 0.0 1.4e-15 57.8 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase ArsA_ATPase PF02374.15 OAF98621.1 - 1.1e-118 395.8 0.2 1.3e-118 395.6 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OAF98621.1 - 9.5e-15 55.0 0.1 8e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 OAF98621.1 - 1.5e-13 50.9 0.0 3e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 OAF98621.1 - 1.3e-06 28.2 0.0 0.00026 20.7 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain ParA PF10609.9 OAF98621.1 - 1.4e-06 28.0 1.2 3.4e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 OAF98621.1 - 1.4e-06 28.0 0.1 3.5e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 OAF98621.1 - 1.2e-05 24.9 0.0 4.5e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ATPase PF06745.13 OAF98621.1 - 0.011 15.1 0.4 0.038 13.3 0.0 1.9 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 OAF98621.1 - 0.019 14.3 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 OAF98621.1 - 0.027 14.1 0.2 0.073 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OAF98621.1 - 0.037 13.5 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein VirC1 PF07015.11 OAF98621.1 - 0.047 13.0 0.1 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 VirC1 protein DUF1515 PF07439.11 OAF98621.1 - 0.062 13.3 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1515) T2SSE PF00437.20 OAF98621.1 - 0.063 12.3 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 OAF98621.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 OAF98621.1 - 0.091 11.9 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase ATP_bind_1 PF03029.17 OAF98621.1 - 0.11 12.3 0.3 0.27 11.0 0.2 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OAF98621.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OAF98621.1 - 0.14 12.7 0.1 0.4 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain MipZ PF09140.11 OAF98621.1 - 0.16 11.3 0.1 0.33 10.2 0.1 1.6 1 1 0 1 1 1 0 ATPase MipZ AAA_24 PF13479.6 OAF98621.1 - 0.16 11.7 0.0 0.7 9.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAF98621.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SNF2_N PF00176.23 OAF98622.1 - 4e-75 252.7 0.8 1.1e-74 251.3 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 OAF98622.1 - 8.9e-41 138.5 5.4 7.4e-40 135.5 1.7 3.0 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 OAF98622.1 - 2.1e-35 121.8 1.4 2.1e-35 121.8 1.4 3.9 5 0 0 5 5 3 1 HAND Helicase_C PF00271.31 OAF98622.1 - 1.3e-18 67.3 0.1 1.4e-17 64.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAF98622.1 - 3.1e-12 46.8 0.2 3e-11 43.6 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 OAF98622.1 - 4.9e-06 26.6 0.2 0.21 11.8 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain SWI2_SNF2 PF18766.1 OAF98622.1 - 4.8e-05 23.1 0.1 0.00023 20.9 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 OAF98622.1 - 0.00013 21.8 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAF98622.1 - 0.00024 20.3 0.0 0.00081 18.6 0.0 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 OAF98622.1 - 0.00043 19.9 0.1 0.0012 18.5 0.1 1.7 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.6 OAF98622.1 - 0.0082 16.2 0.1 0.027 14.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAF98622.1 - 0.13 12.6 1.0 0.79 10.0 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF2231 PF09990.9 OAF98623.1 - 1.2e-06 28.9 0.3 1.2e-06 28.9 0.3 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2231) CorA PF01544.18 OAF98624.1 - 1.5e-11 44.1 6.4 1.5e-11 44.1 6.4 2.9 3 1 0 3 3 3 1 CorA-like Mg2+ transporter protein Sm_multidrug_ex PF06695.11 OAF98624.1 - 0.013 16.1 0.1 0.047 14.3 0.0 1.9 2 0 0 2 2 2 0 Putative small multi-drug export protein DUF2417 PF10329.9 OAF98624.1 - 0.024 14.1 0.8 0.045 13.2 0.8 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) CDH-cyt PF16010.5 OAF98625.1 - 1.1e-45 155.6 4.3 1.3e-45 155.4 4.3 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 OAF98625.1 - 0.065 13.4 0.0 0.2 11.9 0.0 1.8 1 1 1 2 2 2 0 DOMON domain IBR PF01485.21 OAF98626.1 - 0.0011 19.2 7.7 3.1 8.1 0.3 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain Glyco_hydro_28 PF00295.17 OAF98629.1 - 8.6e-41 140.1 3.9 1.8e-39 135.7 3.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short_C2 PF13561.6 OAF98630.1 - 5.7e-52 176.6 0.0 7.7e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAF98630.1 - 2.6e-41 141.2 0.4 3.2e-41 141.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAF98630.1 - 2.9e-11 43.6 0.2 5.3e-11 42.8 0.2 1.3 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 OAF98630.1 - 0.00083 19.5 0.5 0.0015 18.6 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 OAF98630.1 - 0.0012 19.4 0.2 0.0023 18.5 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OAF98630.1 - 0.0016 18.0 0.2 0.0025 17.3 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAF98630.1 - 0.0052 16.0 0.1 0.0072 15.5 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAF98630.1 - 0.012 14.7 0.2 0.016 14.2 0.2 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Dioxygenase_C PF00775.21 OAF98631.1 - 1.9e-07 30.7 0.0 9.8e-06 25.1 0.0 2.3 1 1 0 1 1 1 1 Dioxygenase ECH_1 PF00378.20 OAF98632.1 - 3.9e-43 147.6 0.0 7.2e-43 146.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAF98632.1 - 8.7e-29 101.1 0.0 4.6e-26 92.1 0.0 2.0 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-U1 PF06220.12 OAF98633.1 - 3.9e-22 77.7 3.0 5e-22 77.4 3.0 1.1 1 0 0 1 1 1 1 U1 zinc finger AKAP95 PF04988.12 OAF98633.1 - 0.066 13.4 0.1 0.078 13.2 0.1 1.0 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) HTH_51 PF18558.1 OAF98633.1 - 0.19 11.6 0.0 0.26 11.2 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Actin_micro PF17003.5 OAF98633.1 - 0.23 10.6 0.1 0.26 10.4 0.1 1.0 1 0 0 1 1 1 0 Putative actin-like family NmrA PF05368.13 OAF98634.1 - 5.6e-15 55.5 0.0 6.8e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAF98634.1 - 7.1e-08 32.6 0.0 2.1e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OAF98634.1 - 8.2e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAF98634.1 - 1.7e-06 28.3 0.0 1.6e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAF98634.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 OAF98634.1 - 0.1 13.2 0.0 0.48 11.0 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent WD40 PF00400.32 OAF98635.1 - 2e-44 148.7 24.7 7.7e-09 36.1 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAF98635.1 - 4.3e-09 36.6 0.3 0.076 13.3 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAF98635.1 - 0.00019 20.3 7.7 0.24 10.0 0.1 4.3 2 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAF98635.1 - 0.0012 17.9 0.0 9.4 5.1 0.0 4.0 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAF98635.1 - 0.012 15.5 0.5 22 5.1 0.0 4.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 OAF98635.1 - 0.017 14.5 0.0 0.77 9.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain CH PF00307.31 OAF98636.1 - 2.3e-13 50.3 0.0 4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.16 OAF98637.1 - 1.2e-10 42.1 0.7 1.2e-10 42.1 0.7 2.2 3 0 0 3 3 3 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Glyco_hydro_43 PF04616.14 OAF98639.1 - 3.1e-10 39.9 8.5 4.6e-10 39.3 8.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Isochorismatase PF00857.20 OAF98640.1 - 1.3e-29 103.6 0.0 1.7e-23 83.7 0.0 2.4 2 0 0 2 2 2 2 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.6 OAF98640.1 - 1e-23 84.6 0.5 2.3e-23 83.4 0.5 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.6 OAF98640.1 - 0.0024 17.9 0.1 0.0054 16.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAF98640.1 - 0.05 13.8 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SRAP PF02586.14 OAF98642.1 - 1.2e-82 276.7 0.0 1.7e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) DUF3885 PF13021.6 OAF98642.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Amidase_6 PF12671.7 OAF98642.1 - 0.068 13.3 0.1 0.19 11.8 0.1 1.7 1 1 0 1 1 1 0 Putative amidase domain PAF PF15715.5 OAF98642.1 - 5.9 7.5 13.3 3.4 8.3 5.5 2.3 2 0 0 2 2 2 0 PCNA-associated factor histone like domain TPR_12 PF13424.6 OAF98643.1 - 4.2e-06 27.0 10.2 0.021 15.1 0.2 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAF98643.1 - 1.3e-05 24.9 12.9 0.18 12.0 0.2 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAF98643.1 - 0.00011 22.7 7.8 2.9 8.9 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAF98643.1 - 0.00096 18.6 1.4 0.05 13.0 0.2 2.3 2 0 0 2 2 2 2 MalT-like TPR region RPN7 PF10602.9 OAF98643.1 - 0.031 14.0 0.2 7.2 6.3 0.1 3.2 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 OAF98643.1 - 0.12 12.9 0.5 28 5.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAF98643.1 - 0.61 10.0 9.9 3.9 7.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAF98643.1 - 3.2 8.0 4.9 1.4e+02 2.9 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat OsmC PF02566.19 OAF98644.1 - 1.9e-14 53.9 0.0 2.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein COesterase PF00135.28 OAF98645.1 - 4.9e-58 197.3 0.0 6.4e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAF98645.1 - 0.0069 16.3 0.5 2.8 7.7 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold BatD PF13584.6 OAF98648.1 - 0.0007 18.5 0.1 0.00092 18.1 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance RCR PF12273.8 OAF98648.1 - 0.0077 16.9 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Stevor PF17410.2 OAF98648.1 - 0.042 13.4 0.2 0.058 12.9 0.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame BatA PF07584.11 OAF98648.1 - 0.057 13.8 1.3 0.13 12.6 1.3 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Wzy_C_2 PF11846.8 OAF98648.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF4381 PF14316.6 OAF98648.1 - 0.21 11.8 2.2 0.9 9.8 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Tfb5 PF06331.12 OAF98649.1 - 1.5e-22 79.3 0.6 1.8e-22 79.1 0.6 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 GFA PF04828.14 OAF98650.1 - 4.5e-27 94.2 0.2 5.8e-27 93.9 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Peptidase_C62 PF12380.8 OAF98650.1 - 0.027 13.6 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase Zn_ribbon_recom PF13408.6 OAF98650.1 - 0.078 13.5 3.0 0.72 10.4 0.0 2.9 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain ZF-HD_dimer PF04770.12 OAF98651.1 - 0.3 11.4 3.7 0.51 10.7 3.7 1.4 1 0 0 1 1 1 0 ZF-HD protein dimerisation region Med1 PF10744.9 OAF98652.1 - 3.4e-76 257.0 0.0 4.9e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.24 OAF98653.1 - 6.3e-18 64.9 0.0 1.2e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OAF98653.1 - 2.1e-12 46.6 0.0 5.9e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF134 PF02001.16 OAF98654.1 - 0.12 13.0 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF134 FAD-oxidase_C PF02913.19 OAF98655.1 - 8e-49 166.5 0.0 1.2e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAF98655.1 - 3.9e-32 110.9 0.1 7.8e-32 109.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Asp PF00026.23 OAF98656.1 - 8.6e-28 97.7 0.0 1e-27 97.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAF98656.1 - 0.00035 20.9 0.1 0.016 15.5 0.1 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal F-box-like PF12937.7 OAF98656.1 - 0.042 13.7 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 F-box-like TAXi_C PF14541.6 OAF98656.1 - 0.046 13.5 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal PALP PF00291.25 OAF98657.1 - 2.3e-61 207.8 0.7 2.7e-61 207.6 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AIRC PF00731.20 OAF98657.1 - 0.06 12.9 2.2 2.8 7.5 0.2 3.0 3 0 0 3 3 3 0 AIR carboxylase Pkinase PF00069.25 OAF98659.1 - 3.4e-62 210.2 0.0 4.4e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF98659.1 - 8.9e-32 110.4 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAF98659.1 - 4.8e-05 22.8 0.0 8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAF98659.1 - 0.0011 18.4 0.1 0.0021 17.4 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAF98659.1 - 0.0013 17.6 0.0 0.0024 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAF98659.1 - 0.042 13.8 0.3 0.042 13.8 0.3 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Endonuc_Holl PF10107.9 OAF98659.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Haspin_kinase PF12330.8 OAF98659.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain SRP-alpha_N PF04086.13 OAF98659.1 - 0.28 11.0 1.4 0.41 10.5 1.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ATP-synt_Eps PF04627.13 OAF98661.1 - 0.57 10.2 2.2 22 5.1 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Ank_2 PF12796.7 OAF98662.1 - 8.1e-06 26.3 0.1 0.033 14.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAF98662.1 - 0.00033 20.9 0.1 2.4 9.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat PLN_propep PF16485.5 OAF98662.1 - 0.17 11.6 0.1 6.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Protealysin propeptide Sec39 PF08314.11 OAF98665.1 - 2.9e-255 849.3 0.0 3.4e-255 849.2 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Peptidase_S9 PF00326.21 OAF98666.1 - 0.00093 18.7 0.0 0.029 13.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAF98666.1 - 0.009 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAF98666.1 - 0.062 12.6 0.0 0.87 8.8 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Fib_alpha PF08702.10 OAF98667.1 - 0.062 13.5 7.6 0.022 14.9 3.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Crl PF07417.12 OAF98667.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma factor-binding transcriptional regulator Crl DUF1759 PF03564.15 OAF98667.1 - 0.23 11.4 1.9 0.42 10.5 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) TMF_TATA_bd PF12325.8 OAF98667.1 - 0.67 10.2 11.3 0.14 12.4 2.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.16 OAF98667.1 - 1.2 9.6 9.2 13 6.3 9.2 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF948 PF06103.11 OAF98667.1 - 1.5 9.1 7.6 0.2 11.9 2.6 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 OAF98667.1 - 2.1 7.6 9.4 4.6 6.5 9.4 1.5 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 OAF98667.1 - 3.1 6.8 8.0 6.8 5.7 8.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 OAF98667.1 - 3.4 6.8 5.0 7.2 5.8 5.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 OAF98667.1 - 5 7.8 12.8 0.16 12.6 2.8 2.9 2 1 1 3 3 3 0 SlyX Peptidase_M54 PF07998.11 OAF98670.1 - 4.4e-09 36.6 0.5 7.7e-09 35.8 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M54 zf-C2H2 PF00096.26 OAF98673.1 - 0.0038 17.6 2.9 0.0038 17.6 2.9 3.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAF98673.1 - 1.3 9.6 11.9 3.2 8.4 5.8 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zinc_ribbon_16 PF17034.5 OAF98674.1 - 0.0013 19.0 0.4 0.0013 19.0 0.4 1.1 1 0 0 1 1 1 1 Zinc-ribbon like family Transglut_core3 PF13471.6 OAF98675.1 - 0.077 12.9 0.0 0.33 10.9 0.1 1.8 2 0 0 2 2 2 0 Transglutaminase-like superfamily GFO_IDH_MocA PF01408.22 OAF98677.1 - 5.1e-17 62.8 0.1 7.2e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAF98677.1 - 0.005 17.5 0.1 0.0075 16.9 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4499 PF14934.6 OAF98678.1 - 0.012 15.9 3.0 0.016 15.5 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) DUF3772 PF12607.8 OAF98678.1 - 0.097 12.4 3.1 0.29 10.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Peptidase_C26 PF07722.13 OAF98679.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 NMO PF03060.15 OAF98680.1 - 8.8e-51 173.2 1.6 1.2e-50 172.7 1.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAF98680.1 - 4.5e-08 32.5 3.7 1.8e-07 30.5 3.7 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAF98680.1 - 5.4e-05 22.4 2.4 8e-05 21.8 2.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Taxilin PF09728.9 OAF98681.1 - 5e-90 301.8 63.6 5e-90 301.8 63.6 1.9 1 1 1 2 2 2 1 Myosin-like coiled-coil protein APG6_N PF17675.1 OAF98681.1 - 0.0014 19.2 15.7 0.0014 19.2 15.7 4.8 1 1 3 4 4 4 1 Apg6 coiled-coil region XRCC4 PF06632.12 OAF98681.1 - 0.0064 15.4 19.3 0.0064 15.4 19.3 3.4 1 1 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PRIMA1 PF16101.5 OAF98681.1 - 0.24 11.4 2.8 0.7 9.9 2.8 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMF_TATA_bd PF12325.8 OAF98681.1 - 0.74 10.1 69.1 0.19 12.0 15.8 4.6 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding M16C_assoc PF08367.11 OAF98682.1 - 1.2e-85 286.7 0.1 1.8e-85 286.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OAF98682.1 - 3.2e-29 102.2 0.0 2.7e-19 69.9 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAF98682.1 - 3.7e-08 33.5 0.1 1.4e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Mit_ribos_Mrp51 PF11709.8 OAF98682.1 - 0.11 12.1 0.2 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Erythro_esteras PF05139.14 OAF98682.1 - 0.31 10.8 5.0 0.14 11.9 0.5 2.2 2 0 0 2 2 2 0 Erythromycin esterase DUF5592 PF17332.2 OAF98683.1 - 8 7.1 9.8 25 5.5 1.7 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5592) Acyl_transf_3 PF01757.22 OAF98684.1 - 1.1e-17 64.2 18.4 2.1e-17 63.2 18.0 1.7 1 1 0 1 1 1 1 Acyltransferase family NADH5_C PF06455.11 OAF98684.1 - 0.057 13.0 1.8 2.5 7.7 0.5 2.7 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus PI3_PI4_kinase PF00454.27 OAF98686.1 - 3.8e-39 135.0 0.0 1.3e-36 126.8 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OAF98686.1 - 2.1e-22 79.5 0.2 4e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.26 OAF98687.1 - 1.6e-46 158.2 0.4 4.2e-31 107.9 0.0 2.5 2 1 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 OAF98687.1 - 5.5e-12 45.1 1.0 6.2e-12 45.0 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature His_Phos_1 PF00300.22 OAF98688.1 - 1.1e-15 57.9 0.0 2.4e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SKG6 PF08693.10 OAF98689.1 - 2.9e-07 29.8 1.1 5.7e-07 28.8 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.6 OAF98689.1 - 0.0029 17.8 0.0 0.0079 16.5 0.0 1.7 2 0 0 2 2 2 1 Protein melan-A Plasmodium_Vir PF05795.11 OAF98689.1 - 0.0031 17.0 0.3 0.005 16.3 0.3 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Presenilin PF01080.17 OAF98689.1 - 0.73 8.5 3.7 1 8.0 3.7 1.2 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 OAF98691.1 - 5.2e-49 166.4 0.0 1.4e-48 164.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAF98691.1 - 2.6e-32 111.4 0.0 6e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAF98691.1 - 0.0039 17.2 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAF98691.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Pro_isomerase PF00160.21 OAF98692.1 - 1.6e-49 168.2 0.3 1.9e-49 168.0 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 OAF98693.1 - 5.9e-19 68.7 0.2 5.6e-17 62.3 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 OAF98693.1 - 0.18 10.5 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) RhoGAP PF00620.27 OAF98694.1 - 2.4e-39 134.6 0.1 4e-39 133.9 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OAF98694.1 - 3.7e-13 49.9 0.0 8.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OAF98694.1 - 0.00017 21.9 0.0 0.00039 20.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain EthD PF07110.11 OAF98695.1 - 4e-15 56.7 0.1 7.7e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAF98695.1 - 1.2e-05 25.7 0.0 1.9e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase GXGXG PF01493.19 OAF98695.1 - 0.072 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 GXGXG motif NatB_MDM20 PF09797.9 OAF98696.1 - 2.8e-32 112.1 0.0 4.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit tRNA-synt_1g PF09334.11 OAF98697.1 - 4.9e-91 305.4 0.0 6.6e-90 301.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAF98697.1 - 6.8e-20 70.9 0.2 1.2e-09 37.0 0.0 3.2 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OAF98697.1 - 0.016 14.6 0.0 3.2 7.0 0.0 2.4 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Apidaecin PF00807.17 OAF98698.1 - 2.7 8.2 11.1 2.5 8.3 4.8 3.1 2 1 1 3 3 3 0 Apidaecin Ornatin PF02088.15 OAF98698.1 - 4.9 7.0 6.6 5.3 6.9 0.1 2.4 3 0 0 3 3 3 0 Ornatin SAM_2 PF07647.17 OAF98699.1 - 7.4e-10 38.8 0.2 1.4e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAF98699.1 - 2.8e-07 30.8 0.2 5.9e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 OAF98699.1 - 7.3e-06 26.4 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_3 PF18016.1 OAF98699.1 - 0.00019 21.2 0.0 0.00052 19.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pou PF00157.17 OAF98699.1 - 0.095 12.7 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain SAM_Ste50p PF09235.10 OAF98699.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Fungal_trans_2 PF11951.8 OAF98700.1 - 5.5e-85 285.5 0.0 6.9e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF98700.1 - 1.4e-07 31.5 8.8 2.8e-07 30.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_14 PF13428.6 OAF98702.1 - 3e-13 49.4 1.4 0.025 15.4 0.2 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat Suf PF05843.14 OAF98702.1 - 1.3e-06 28.7 7.0 0.00018 21.6 0.0 3.2 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) LMBR1 PF04791.16 OAF98702.1 - 0.096 11.6 0.3 0.34 9.7 0.2 2.0 3 0 0 3 3 3 0 LMBR1-like membrane protein HAT PF02184.16 OAF98702.1 - 0.16 12.0 12.7 7.5 6.6 0.0 5.8 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat G_glu_transpept PF01019.21 OAF98703.1 - 1.3e-161 538.9 0.2 1.5e-161 538.7 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1344 PF07076.11 OAF98703.1 - 0.077 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF2235 PF09994.9 OAF98704.1 - 6e-100 334.3 0.0 7.9e-100 333.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Cytochrom_C1 PF02167.15 OAF98705.1 - 4.1e-93 311.1 0.0 4.9e-93 310.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OAF98705.1 - 0.01 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OAF98705.1 - 0.15 13.2 0.5 0.62 11.3 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c Peptidase_M48_N PF16491.5 OAF98706.1 - 4.5e-63 212.4 5.4 4.5e-63 212.4 5.4 1.5 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OAF98706.1 - 3.3e-45 154.3 0.0 9.3e-45 152.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 OAF98706.1 - 6.4e-05 22.3 0.7 0.00028 20.2 0.7 1.9 2 1 0 2 2 2 1 BlaR1 peptidase M56 SprT-like PF10263.9 OAF98706.1 - 0.046 13.6 0.1 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 OAF98706.1 - 0.073 13.0 0.1 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 IrrE N-terminal-like domain DUF4538 PF15061.6 OAF98706.1 - 0.28 10.9 1.0 0.69 9.7 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) ATP11 PF06644.11 OAF98707.1 - 2.6e-90 302.9 0.0 3e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein 3Beta_HSD PF01073.19 OAF98708.1 - 6e-53 179.7 0.0 4.1e-43 147.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAF98708.1 - 1.1e-31 110.2 0.0 7.6e-20 71.4 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAF98708.1 - 4.3e-18 65.8 0.0 1.1e-09 38.2 0.0 2.3 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAF98708.1 - 1.3e-13 50.7 0.3 5.2e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAF98708.1 - 1.1e-12 47.6 0.0 2.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 OAF98708.1 - 1.9e-10 40.9 0.0 4e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAF98708.1 - 1.7e-09 37.3 0.0 0.025 13.7 0.0 3.3 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein KR PF08659.10 OAF98708.1 - 2.2e-06 27.7 0.5 0.031 14.2 0.2 3.0 2 1 0 2 2 2 2 KR domain NmrA PF05368.13 OAF98708.1 - 0.00013 21.6 0.0 0.004 16.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 OAF98708.1 - 0.0068 15.9 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Acetyltransf_3 PF13302.7 OAF98709.1 - 2.5e-25 89.7 0.0 3.8e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAF98709.1 - 0.00063 19.4 0.8 1.5 8.5 0.3 3.0 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAF98709.1 - 0.18 11.9 0.0 0.86 9.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA PF00004.29 OAF98710.1 - 9.3e-43 145.8 0.0 1.5e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAF98710.1 - 1.1e-10 41.3 0.1 3.8e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAF98710.1 - 1.4e-10 40.8 0.1 3.2e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAF98710.1 - 1e-07 32.5 0.0 5.7e-05 23.6 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAF98710.1 - 1.8e-06 28.0 0.1 3.2e-05 23.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAF98710.1 - 2.9e-06 27.5 0.0 9.4e-06 25.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAF98710.1 - 7.1e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAF98710.1 - 0.00019 21.7 0.1 0.0036 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAF98710.1 - 0.00039 19.7 0.0 0.00085 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAF98710.1 - 0.00093 19.8 0.1 0.0028 18.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 OAF98710.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 OAF98710.1 - 0.0024 17.1 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAF98710.1 - 0.004 17.3 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAF98710.1 - 0.0042 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OAF98710.1 - 0.0045 17.0 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OAF98710.1 - 0.0061 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 OAF98710.1 - 0.0062 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 OAF98710.1 - 0.0074 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAF98710.1 - 0.0079 15.9 0.0 0.028 14.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAF98710.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OAF98710.1 - 0.023 14.1 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 OAF98710.1 - 0.029 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAF98710.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 OAF98710.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NACHT PF05729.12 OAF98710.1 - 0.054 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 OAF98710.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OAF98710.1 - 0.094 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAF98710.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAF98710.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 OAF98710.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OAF98710.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 eIF-1a PF01176.19 OAF98710.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 WD40 PF00400.32 OAF98711.1 - 1.8e-14 53.8 5.8 0.1 13.5 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat AP3D1 PF06375.11 OAF98711.1 - 3.1 8.0 7.3 3.8 7.7 5.8 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Cwf_Cwc_15 PF04889.12 OAF98711.1 - 3.9 7.2 12.1 6.7 6.4 12.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pro_isomerase PF00160.21 OAF98712.1 - 6.7e-51 172.7 0.1 1.7e-50 171.4 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OAF98712.1 - 9.2e-11 42.1 0.0 4.3e-05 24.2 0.0 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAF98712.1 - 0.00034 20.9 0.0 0.35 11.2 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAF98712.1 - 0.016 14.2 0.4 2.4 7.0 0.1 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_binding_1 PF01035.20 OAF98712.1 - 0.082 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain eIF2_C PF09173.11 OAF98714.1 - 3e-34 117.1 0.3 6.7e-34 116.0 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OAF98714.1 - 3.2e-23 82.3 0.1 2e-22 79.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAF98714.1 - 2.5e-12 47.0 0.2 5.2e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAF98714.1 - 0.0037 17.3 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAF98714.1 - 0.008 16.1 0.2 0.079 12.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OAF98714.1 - 0.15 12.1 0.0 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Aminotran_3 PF00202.21 OAF98716.1 - 5.7e-120 400.7 0.0 6.6e-120 400.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAF98716.1 - 0.00081 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAF98716.1 - 0.00094 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase UPF0556 PF10572.9 OAF98716.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 OAM_dimer PF16554.5 OAF98716.1 - 0.17 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase ABC_membrane PF00664.23 OAF98717.1 - 1.5e-53 182.3 37.2 4e-36 125.1 17.8 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 OAF98717.1 - 4e-46 156.9 0.0 1.7e-26 93.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 OAF98717.1 - 6.2e-06 25.6 0.0 0.00098 18.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 OAF98717.1 - 4.4e-05 23.5 2.1 0.091 12.8 0.2 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase SMC_N PF02463.19 OAF98717.1 - 5.7e-05 22.7 3.5 0.6 9.5 0.4 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 OAF98717.1 - 0.0011 19.2 3.8 0.017 15.2 0.4 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 OAF98717.1 - 0.0012 19.2 0.4 1.6 9.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAF98717.1 - 0.0019 17.9 1.5 0.97 9.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAF98717.1 - 0.0032 17.3 1.3 3.2 7.5 0.1 3.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 OAF98717.1 - 0.0077 16.3 7.2 0.058 13.4 0.3 3.1 3 0 0 3 3 3 1 Dynamin family AAA_30 PF13604.6 OAF98717.1 - 0.0088 15.8 2.5 2.5 7.8 0.1 2.7 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 OAF98717.1 - 0.014 15.3 2.3 2.6 7.9 0.2 2.6 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 OAF98717.1 - 0.023 13.7 1.3 3.5 6.5 0.1 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 OAF98717.1 - 0.042 13.8 0.3 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 OAF98717.1 - 0.059 13.7 3.3 11 6.2 0.6 3.6 3 1 0 3 3 2 0 AAA domain Roc PF08477.13 OAF98717.1 - 0.089 13.0 0.1 17 5.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 OAF98717.1 - 0.09 12.3 0.3 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IIGP PF05049.13 OAF98717.1 - 0.11 11.6 1.2 1.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) T2SSE PF00437.20 OAF98717.1 - 0.12 11.4 0.1 1 8.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 OAF98717.1 - 0.24 10.7 0.8 13 5.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 OAF98717.1 - 0.4 10.4 3.8 5.9 6.6 0.2 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 OAF98717.1 - 0.4 11.1 8.5 11 6.5 0.1 3.5 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 OAF98717.1 - 2 7.2 4.6 6.5 5.5 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain PRK PF00485.18 OAF98717.1 - 4.5 7.0 6.1 37 4.0 0.7 3.5 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Nop25 PF09805.9 OAF98719.1 - 2.1e-37 128.7 7.2 2.1e-37 128.7 7.2 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) LMBR1 PF04791.16 OAF98719.1 - 6 5.6 6.6 7.2 5.4 6.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Prenyltrans PF00432.21 OAF98720.1 - 8e-27 92.7 4.5 3.3e-06 26.7 0.0 6.0 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OAF98720.1 - 0.0012 18.0 0.0 0.0044 16.2 0.0 1.8 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 OAF98720.1 - 0.017 14.2 0.0 0.48 9.4 0.0 2.7 3 1 0 3 3 3 0 A-macroglobulin TED domain RhoGAP PF00620.27 OAF98721.1 - 3.6e-17 62.6 0.2 9.4e-17 61.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 OAF98721.1 - 1e-12 47.9 0.0 2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 OAF98721.1 - 4.6e-09 36.4 0.1 3.1e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF747 PF05346.11 OAF98721.1 - 0.22 10.9 0.7 0.34 10.3 0.7 1.2 1 0 0 1 1 1 0 Eukaryotic membrane protein family Tropomyosin_1 PF12718.7 OAF98722.1 - 3.5e-51 173.1 28.8 4e-51 172.9 28.8 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 OAF98722.1 - 1.1e-09 38.1 29.6 1.2e-05 24.8 5.7 3.0 1 1 2 3 3 3 3 Tropomyosin HMMR_N PF15905.5 OAF98722.1 - 0.00044 19.8 27.0 0.00078 19.0 27.0 1.5 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal KLRAQ PF10205.9 OAF98722.1 - 0.00066 19.9 8.8 0.00066 19.9 8.8 2.2 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein DUF812 PF05667.11 OAF98722.1 - 0.00087 18.3 23.7 0.0011 17.9 23.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 OAF98722.1 - 0.0011 19.2 21.1 0.049 13.9 12.4 2.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding GAS PF13851.6 OAF98722.1 - 0.0015 18.0 25.8 0.054 12.8 15.2 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.19 OAF98722.1 - 0.0049 14.8 24.1 0.0056 14.6 24.1 1.0 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.11 OAF98722.1 - 0.0051 17.1 27.7 0.049 13.9 9.8 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) KxDL PF10241.9 OAF98722.1 - 0.0053 17.0 11.7 0.0071 16.6 0.8 3.3 1 1 2 3 3 2 1 Uncharacterized conserved protein Fez1 PF06818.15 OAF98722.1 - 0.0058 17.1 23.1 0.0061 17.0 22.4 1.4 1 1 0 1 1 1 1 Fez1 DUF3450 PF11932.8 OAF98722.1 - 0.0061 15.9 25.8 0.045 13.0 9.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) DivIC PF04977.15 OAF98722.1 - 0.0088 15.8 3.6 0.0088 15.8 3.6 3.8 2 2 2 4 4 4 1 Septum formation initiator Laminin_II PF06009.12 OAF98722.1 - 0.012 15.7 3.7 0.012 15.7 3.7 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF5595 PF18077.1 OAF98722.1 - 0.017 15.2 4.4 0.017 15.2 4.4 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5595) BRE1 PF08647.11 OAF98722.1 - 0.018 15.1 30.6 0.13 12.4 11.5 3.0 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase ADIP PF11559.8 OAF98722.1 - 0.018 15.1 24.7 0.085 12.9 8.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 OAF98722.1 - 0.02 14.7 32.9 0.061 13.1 12.5 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4200 PF13863.6 OAF98722.1 - 0.022 15.1 31.6 0.17 12.3 11.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) GIT_CC PF16559.5 OAF98722.1 - 0.025 14.4 8.1 8.1 6.4 0.1 3.7 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Taxilin PF09728.9 OAF98722.1 - 0.026 13.7 26.4 0.049 12.8 9.8 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Spc7 PF08317.11 OAF98722.1 - 0.028 13.3 29.0 0.25 10.2 11.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 OAF98722.1 - 0.03 14.4 16.3 0.084 12.9 3.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 OAF98722.1 - 0.035 14.2 1.6 0.035 14.2 1.6 4.3 2 2 2 4 4 4 0 bZIP transcription factor BLOC1_2 PF10046.9 OAF98722.1 - 0.036 14.4 21.2 0.22 11.8 2.9 3.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 OAF98722.1 - 0.04 13.3 19.5 0.06 12.7 19.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 OAF98722.1 - 0.046 13.7 29.8 0.43 10.6 12.5 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 OAF98722.1 - 0.051 13.7 27.2 0.21 11.7 11.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Vps53_N PF04100.12 OAF98722.1 - 0.052 12.5 8.4 0.029 13.3 6.4 1.6 1 1 0 1 1 1 0 Vps53-like, N-terminal Laminin_I PF06008.14 OAF98722.1 - 0.059 13.1 20.8 0.56 9.9 20.9 2.4 1 1 0 1 1 1 0 Laminin Domain I SHE3 PF17078.5 OAF98722.1 - 0.065 12.9 17.7 0.088 12.5 17.7 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 OAF98722.1 - 0.068 13.2 27.9 0.079 13.0 2.4 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_C PF15908.5 OAF98722.1 - 0.08 13.2 15.9 0.08 13.2 2.9 2.7 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Jnk-SapK_ap_N PF09744.9 OAF98722.1 - 0.081 13.1 26.4 0.016 15.4 14.8 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HOOK PF05622.12 OAF98722.1 - 0.087 11.0 22.8 0.11 10.7 22.8 1.1 1 0 0 1 1 1 0 HOOK protein CLZ PF16526.5 OAF98722.1 - 0.091 13.1 20.4 0.41 11.0 1.4 3.9 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lebercilin PF15619.6 OAF98722.1 - 0.1 12.3 25.3 0.16 11.6 11.6 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MS_channel PF00924.18 OAF98722.1 - 0.1 12.2 1.0 0.14 11.7 0.9 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel DUF4201 PF13870.6 OAF98722.1 - 0.12 12.1 21.9 2.1 8.0 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) CtIP_N PF10482.9 OAF98722.1 - 0.12 12.4 16.7 0.31 11.1 12.1 2.6 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain CEP63 PF17045.5 OAF98722.1 - 0.14 12.0 22.1 0.38 10.6 22.1 1.6 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa WXG100 PF06013.12 OAF98722.1 - 0.17 12.2 14.8 1.6 9.1 3.9 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF724 PF05266.14 OAF98722.1 - 0.17 11.7 24.5 0.43 10.4 8.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Uso1_p115_C PF04871.13 OAF98722.1 - 0.18 12.2 30.5 0.96 9.8 10.9 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DHR10 PF18595.1 OAF98722.1 - 0.19 11.8 29.5 0.94 9.5 11.9 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CALCOCO1 PF07888.11 OAF98722.1 - 0.19 10.5 26.8 0.096 11.5 17.9 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 OAF98722.1 - 0.21 12.1 34.0 3.2 8.3 13.6 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 OAF98722.1 - 0.22 11.6 21.7 0.4 10.8 7.6 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 SlyX PF04102.12 OAF98722.1 - 0.24 12.0 17.2 1.8 9.2 5.2 3.1 2 2 1 3 3 2 0 SlyX NPV_P10 PF05531.12 OAF98722.1 - 0.26 11.8 9.8 1.3 9.6 0.9 3.6 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein HAP1_N PF04849.13 OAF98722.1 - 0.26 10.4 21.7 0.56 9.4 21.7 2.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF641 PF04859.12 OAF98722.1 - 0.26 11.6 20.3 0.36 11.2 7.2 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Syntaxin-6_N PF09177.11 OAF98722.1 - 0.26 11.9 17.6 0.31 11.6 5.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TACC_C PF05010.14 OAF98722.1 - 0.26 11.0 24.4 2.8 7.7 21.9 2.9 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3584 PF12128.8 OAF98722.1 - 0.27 8.7 23.5 0.32 8.5 23.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fungal_TACC PF12709.7 OAF98722.1 - 0.29 11.6 23.0 0.31 11.5 5.1 4.0 2 2 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins CENP-K PF11802.8 OAF98722.1 - 0.29 10.7 18.1 1.7 8.2 18.2 1.9 1 1 0 1 1 1 0 Centromere-associated protein K ZapB PF06005.12 OAF98722.1 - 0.3 11.6 29.9 2.2 8.8 10.3 3.5 2 2 1 3 3 3 0 Cell division protein ZapB Rootletin PF15035.6 OAF98722.1 - 0.3 11.1 24.3 0.073 13.1 6.8 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.11 OAF98722.1 - 0.36 11.2 19.1 0.52 10.8 4.7 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 OAF98722.1 - 0.65 9.8 25.5 2.3 8.0 21.3 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FUSC PF04632.12 OAF98722.1 - 0.67 8.4 5.7 0.81 8.2 5.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HigB-like_toxin PF05015.13 OAF98722.1 - 0.84 10.1 5.2 5 7.6 0.1 2.9 1 1 2 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB XhlA PF10779.9 OAF98722.1 - 0.89 9.8 21.2 1.5 9.1 1.1 4.0 3 1 1 4 4 4 0 Haemolysin XhlA Fib_alpha PF08702.10 OAF98722.1 - 0.95 9.6 17.0 0.35 11.0 3.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 OAF98722.1 - 0.96 8.0 22.8 1.5 7.4 8.7 1.8 1 1 0 1 1 1 0 AAA domain Ax_dynein_light PF10211.9 OAF98722.1 - 0.98 9.3 29.2 1 9.2 2.5 3.4 1 1 2 3 3 3 0 Axonemal dynein light chain DUF4472 PF14739.6 OAF98722.1 - 0.98 10.2 23.7 0.95 10.2 8.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) TRAF_BIRC3_bd PF16673.5 OAF98722.1 - 1 9.2 15.5 1.1 9.1 2.7 3.5 1 1 2 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain TPR_MLP1_2 PF07926.12 OAF98722.1 - 1.1 9.4 33.0 10 6.2 12.3 3.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.12 OAF98722.1 - 1.1 8.8 27.1 2.9 7.4 19.4 2.2 1 1 1 2 2 2 0 PspA/IM30 family Filament PF00038.21 OAF98722.1 - 1.2 8.7 24.4 0.88 9.1 8.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein Cortex-I_coil PF09304.10 OAF98722.1 - 1.2 9.4 19.5 7.1 6.9 4.7 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil EzrA PF06160.12 OAF98722.1 - 1.3 7.1 24.0 0.59 8.2 6.9 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Sec34 PF04136.15 OAF98722.1 - 1.4 8.8 14.9 0.2 11.6 2.2 2.1 2 0 0 2 2 2 0 Sec34-like family Atg14 PF10186.9 OAF98722.1 - 1.5 7.8 21.7 0.56 9.2 7.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2937 PF11157.8 OAF98722.1 - 1.5 8.5 7.5 5.3 6.7 4.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2937) Fmp27_WPPW PF10359.9 OAF98722.1 - 1.6 7.5 22.5 1 8.1 6.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain YabA PF06156.13 OAF98722.1 - 1.7 9.3 18.8 6.8 7.4 6.6 2.8 1 1 1 2 2 2 0 Initiation control protein YabA LPP PF04728.13 OAF98722.1 - 1.9 8.9 15.8 1.6 9.2 0.3 4.0 2 2 1 3 3 3 0 Lipoprotein leucine-zipper Med4 PF10018.9 OAF98722.1 - 2.4 7.8 19.3 0.61 9.7 6.4 2.4 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Sipho_Gp157 PF05565.11 OAF98722.1 - 2.5 8.1 23.8 0.12 12.4 8.5 2.6 1 1 2 3 3 3 0 Siphovirus Gp157 TMPIT PF07851.13 OAF98722.1 - 2.6 7.2 20.9 6.8 5.8 6.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 OAF98722.1 - 2.9 8.4 23.0 16 6.0 16.9 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) STAT_alpha PF01017.20 OAF98722.1 - 2.9 7.7 19.3 0.4 10.6 1.3 2.6 1 1 0 2 2 2 0 STAT protein, all-alpha domain Seryl_tRNA_N PF02403.22 OAF98722.1 - 3.1 8.1 23.5 8.3 6.7 0.3 3.2 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Occludin_ELL PF07303.13 OAF98722.1 - 4.2 8.2 19.4 1.2 9.9 2.4 3.0 1 1 2 3 3 3 0 Occludin homology domain MPS2 PF17060.5 OAF98722.1 - 4.5 6.4 15.9 9.5 5.4 15.7 1.6 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF4795 PF16043.5 OAF98722.1 - 5 6.7 21.9 1.1e+02 2.2 21.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Lectin_N PF03954.14 OAF98722.1 - 5.3 6.8 13.6 16 5.3 0.2 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain SOGA PF11365.8 OAF98722.1 - 5.6 8.2 17.9 5.9 8.1 12.8 2.7 1 1 2 3 3 3 0 Protein SOGA Phage_GPO PF05929.11 OAF98722.1 - 5.9 6.4 20.2 2.3 7.8 13.9 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Sec8_exocyst PF04048.14 OAF98722.1 - 6.1 6.7 13.5 1.6 8.6 2.7 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF948 PF06103.11 OAF98722.1 - 7.1 7.0 13.0 16 5.8 3.6 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 OAF98722.1 - 7.2 6.8 18.1 2.3 8.4 4.8 3.8 2 1 2 4 4 4 0 TolA binding protein trimerisation DUF16 PF01519.16 OAF98722.1 - 7.3 7.1 19.8 3.7 8.1 5.2 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 She9_MDM33 PF05546.11 OAF98722.1 - 7.4 6.3 20.2 1.7 8.4 7.8 2.2 1 1 1 2 2 2 0 She9 / Mdm33 family DUF5320 PF17253.2 OAF98722.1 - 7.5 7.7 14.0 3.8 8.6 2.7 2.9 2 1 1 3 3 2 0 Family of unknown function (DUF5320) Prefoldin_2 PF01920.20 OAF98722.1 - 7.5 6.6 30.4 75 3.3 9.0 3.9 2 2 1 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.19 OAF98722.1 - 8.6 4.1 20.8 0.78 7.6 6.1 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 OAF98722.1 - 9.7 6.4 25.9 83 3.4 6.5 4.0 1 1 1 2 2 1 0 Swi5 Sec20 PF03908.13 OAF98722.1 - 10 6.2 9.7 2.1 8.3 1.3 2.8 2 2 1 3 3 3 0 Sec20 SWIB PF02201.18 OAF98724.1 - 8.6e-30 102.4 0.2 1.5e-29 101.7 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 OAF98724.1 - 3.7e-14 52.4 0.5 1.5e-13 50.4 0.2 2.1 2 0 0 2 2 2 1 DEK C terminal domain DTHCT PF08070.11 OAF98724.1 - 0.021 15.5 9.2 0.021 15.5 9.2 2.5 1 1 1 2 2 2 0 DTHCT (NUC029) region SRP54_N PF02881.19 OAF98724.1 - 0.028 14.7 0.1 1.8 8.8 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Sec10 PF07393.11 OAF98725.1 - 1.1e-161 539.8 0.0 1.3e-161 539.5 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 OAF98725.1 - 4.5e-05 23.2 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAF98725.1 - 6.1e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like CFEM PF05730.11 OAF98726.1 - 2.2e-14 53.3 9.5 2.2e-14 53.3 9.5 2.2 2 0 0 2 2 2 1 CFEM domain DUF515 PF04415.12 OAF98726.1 - 2.3 6.5 9.5 2.5 6.4 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ArfGap PF01412.18 OAF98727.1 - 2.5e-33 114.6 0.0 2.5e-33 114.6 0.0 2.3 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 OAF98727.1 - 4.2e-18 65.9 13.6 6.8e-18 65.2 13.6 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 OAF98727.1 - 3.8e-12 46.6 0.7 9.8e-12 45.3 0.1 2.0 2 0 0 2 2 2 1 PH domain BCIP PF13862.6 OAF98727.1 - 0.078 12.7 1.9 0.2 11.4 1.9 1.6 1 0 0 1 1 1 0 p21-C-terminal region-binding protein eIF2A PF08662.11 OAF98728.1 - 1.1e-41 142.9 0.7 4.9e-37 127.7 0.0 4.0 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 OAF98728.1 - 0.00064 19.5 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF61 PF01886.16 OAF98728.1 - 0.073 13.1 2.4 0.16 12.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF61 DUF2497 PF10691.9 OAF98728.1 - 4.9 7.7 7.6 0.16 12.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Response_reg PF00072.24 OAF98729.1 - 1.8e-21 76.4 0.2 4.8e-21 75.0 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAF98729.1 - 1.7e-19 70.4 0.0 4.5e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAF98729.1 - 8.6e-07 28.9 0.1 2.4e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain E1-E2_ATPase PF00122.20 OAF98730.1 - 3.3e-53 179.9 3.5 5.9e-52 175.8 1.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAF98730.1 - 1.6e-46 158.3 4.7 3.7e-46 157.1 4.7 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAF98730.1 - 9.2e-23 81.6 2.3 5.3e-22 79.1 2.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAF98730.1 - 7.8e-21 74.0 0.0 1.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAF98730.1 - 5.1e-20 70.9 0.1 2.1e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAF98730.1 - 1e-08 35.3 0.7 1.3e-06 28.4 0.7 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAF98730.1 - 5.3e-06 27.0 0.0 1.5e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cytokin_check_N PF10407.9 OAF98731.1 - 0.00022 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus SAP PF02037.27 OAF98731.1 - 0.023 14.4 5.2 0.065 13.0 5.2 1.8 1 1 0 1 1 1 0 SAP domain MutS_V PF00488.21 OAF98732.1 - 2.6e-72 242.8 0.0 5.7e-72 241.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAF98732.1 - 5.2e-34 118.1 1.1 1.4e-33 116.7 1.1 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAF98732.1 - 3.3e-29 101.4 0.1 7.4e-29 100.3 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAF98732.1 - 1.5e-10 41.5 0.0 6.6e-10 39.4 0.0 2.2 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAF98732.1 - 7.1e-08 32.7 0.1 3.8e-07 30.3 0.1 2.4 1 0 0 1 1 1 1 MutS family domain IV Caskin-tail PF16632.5 OAF98732.1 - 0.11 13.0 2.1 2.7 8.5 0.2 3.6 3 0 0 3 3 3 0 C-terminal region of Caskin AAA_16 PF13191.6 OAF98733.1 - 1.4e-11 45.1 1.4 1.8e-09 38.2 0.3 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAF98733.1 - 3.1e-08 34.0 0.0 9.9e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.11 OAF98733.1 - 1.3e-07 31.5 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA PF00004.29 OAF98733.1 - 1.6e-07 31.8 0.0 4.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 OAF98733.1 - 1.4e-05 25.2 0.1 2.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 OAF98733.1 - 0.0024 18.2 1.3 0.01 16.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAF98733.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 OAF98733.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 OAF98733.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAF98733.1 - 0.074 13.0 0.0 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAF98733.1 - 0.096 12.4 0.0 0.32 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Syja_N PF02383.18 OAF98735.1 - 2.9e-77 260.1 0.0 4.4e-77 259.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 OAF98735.1 - 3.4e-09 36.6 0.0 8.5e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family APG5 PF04106.12 OAF98736.1 - 8.6e-65 218.5 0.0 1.4e-64 217.8 0.0 1.3 2 0 0 2 2 2 1 Autophagy protein Apg5 DUF5546 PF17700.1 OAF98737.1 - 0.088 13.2 0.7 0.088 13.2 0.7 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5546) MT0933_antitox PF14013.6 OAF98738.1 - 3 8.2 11.4 5.1 7.5 7.4 2.9 2 2 1 3 3 3 0 MT0933-like antitoxin protein cobW PF02492.19 OAF98739.1 - 9.4e-42 142.6 0.0 1.7e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAF98739.1 - 0.0002 21.2 0.0 0.02 14.8 0.0 2.9 2 1 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 OAF98739.1 - 0.00046 20.1 0.0 0.00096 19.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 OAF98739.1 - 0.0035 17.6 0.0 0.03 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAF98739.1 - 0.028 14.2 0.2 0.34 10.7 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 OAF98739.1 - 0.042 13.6 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 OAF98739.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 OAF98739.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Spherulin4 PF12138.8 OAF98740.1 - 9.5e-53 179.3 0.3 1.1e-52 179.1 0.3 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Colicin_Pyocin PF01320.18 OAF98740.1 - 0.037 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein 2OG-FeII_Oxy_3 PF13640.6 OAF98741.1 - 3.8e-11 43.7 0.0 6.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cyclin PF08613.11 OAF98742.1 - 2.3e-38 132.1 8.1 5.3e-24 85.4 0.5 3.0 3 1 1 4 4 4 2 Cyclin Proteasome PF00227.26 OAF98743.1 - 3.4e-46 157.1 1.1 3.9e-46 156.9 1.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase_4 PF12146.8 OAF98744.1 - 1.9e-17 63.4 0.0 7.1e-12 45.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAF98744.1 - 3.3e-11 43.3 0.0 4.6e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 OAF98744.1 - 4.2e-07 29.0 0.1 0.023 13.4 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAF98744.1 - 1.2e-05 26.1 0.0 2.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 OAF98744.1 - 6.8e-05 22.6 0.0 0.00016 21.4 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 OAF98744.1 - 0.00058 19.4 0.0 0.0038 16.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAF98744.1 - 0.0024 17.7 0.1 0.31 10.8 0.1 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 OAF98744.1 - 0.0033 16.5 0.1 0.0043 16.1 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 OAF98744.1 - 0.0043 16.9 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAF98744.1 - 0.022 14.3 0.0 0.35 10.4 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 OAF98744.1 - 0.12 12.3 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.12 OAF98744.1 - 0.19 10.5 0.0 0.38 9.5 0.0 1.5 1 0 0 1 1 1 0 Serine carboxypeptidase S28 YTH PF04146.15 OAF98745.1 - 1e-62 210.9 0.0 1.6e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 OAF98745.1 - 1.6e-06 27.8 0.0 4.2e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Velvet PF11754.8 OAF98747.1 - 1.5e-90 303.5 0.0 2.1e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Mnd1 PF03962.15 OAF98748.1 - 2.6e-22 78.8 2.6 2.9e-22 78.7 0.1 2.2 2 0 0 2 2 2 1 Mnd1 HTH domain zf-C3HC4_3 PF13920.6 OAF98748.1 - 8.3e-06 25.6 9.8 8.3e-06 25.6 9.8 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) LZ3wCH PF18517.1 OAF98748.1 - 0.069 13.2 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Leucine zipper with capping helix domain ZapD PF07072.11 OAF98748.1 - 0.22 11.2 1.6 0.49 10.1 1.6 1.5 1 0 0 1 1 1 0 Cell division protein Cytochrom_B562 PF07361.11 OAF98748.1 - 0.97 10.1 4.4 0.72 10.5 1.6 2.2 2 0 0 2 2 2 0 Cytochrome b562 UAF_Rrn10 PF05234.11 OAF98749.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 UAF complex subunit Rrn10 Imm1 PF14430.6 OAF98749.1 - 0.023 15.4 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm1 WD40 PF00400.32 OAF98750.1 - 1e-22 80.0 13.2 5.1e-05 23.9 0.6 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAF98750.1 - 8.1e-13 48.5 0.0 0.059 13.7 0.0 5.5 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain DRY_EERY PF09750.9 OAF98750.1 - 0.074 13.3 1.7 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 Alternative splicing regulator Methyltransf_16 PF10294.9 OAF98752.1 - 1.1e-33 116.4 0.0 2e-33 115.6 0.0 1.3 1 1 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 OAF98752.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAF98752.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 OAF98752.1 - 0.063 14.0 0.0 0.17 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAF98752.1 - 0.079 13.7 0.1 0.15 12.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3176 PF11374.8 OAF98754.1 - 3.5e-36 123.6 0.5 8.9e-36 122.4 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Rubis-subs-bind PF09273.11 OAF98756.1 - 1.5e-20 74.2 0.0 2.1e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OAF98756.1 - 5.6e-06 26.8 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 SET domain Gln-synt_N_2 PF16952.5 OAF98756.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain YabA PF06156.13 OAF98757.1 - 0.053 14.2 1.3 0.051 14.2 1.3 1.0 1 0 0 1 1 1 0 Initiation control protein YabA HTH_Tnp_Tc5 PF03221.16 OAF98758.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3788 PF12663.7 OAF98758.1 - 0.0083 16.1 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3788) Metallophos PF00149.28 OAF98759.1 - 3.1e-18 67.0 0.0 8.4e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OAF98759.1 - 2.2e-13 50.6 4.0 4.7e-13 49.5 4.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OAF98759.1 - 6.7e-11 42.9 0.8 1.4e-10 41.8 0.2 1.9 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD_N PF16655.5 OAF98759.1 - 0.0021 18.6 0.2 0.0048 17.4 0.2 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 OAF98759.1 - 0.044 14.1 2.9 0.056 13.8 1.7 1.8 2 0 0 2 2 2 0 Fibronectin type III domain PhoD PF09423.10 OAF98759.1 - 0.05 12.6 0.0 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 PhoD-like phosphatase CTU2 PF10288.9 OAF98760.1 - 1e-14 54.7 0.1 1.6e-12 47.7 0.0 2.5 2 0 0 2 2 2 2 Cytoplasmic tRNA 2-thiolation protein 2 WHIM1 PF15612.6 OAF98760.1 - 0.06 12.9 0.0 0.22 11.1 0.0 2.0 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DZR PF12773.7 OAF98760.1 - 0.076 13.1 2.5 0.54 10.3 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon ATP_bind_3 PF01171.20 OAF98760.1 - 0.14 11.9 0.0 15 5.3 0.1 2.3 2 0 0 2 2 2 0 PP-loop family Lung_7-TM_R PF06814.13 OAF98761.1 - 2.4e-69 233.8 17.4 3.3e-69 233.4 17.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor TraA PF05513.11 OAF98761.1 - 0.27 11.6 2.4 0.4 11.0 0.5 2.2 2 0 0 2 2 2 0 TraA GCV_T PF01571.21 OAF98762.1 - 4.2e-06 26.3 0.0 5.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Molybdopterin_N PF18364.1 OAF98762.1 - 0.033 14.2 0.1 0.9 9.6 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain DIOX_N PF14226.6 OAF98763.1 - 0.0092 16.7 0.1 0.029 15.1 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal DCP2 PF05026.13 OAF98764.1 - 2.2e-30 104.8 2.8 3.6e-30 104.1 2.8 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OAF98764.1 - 1.7e-14 54.0 0.0 3.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain SUZ PF12752.7 OAF98764.1 - 4.9 8.0 5.3 51 4.7 0.2 3.3 1 1 1 2 2 2 0 SUZ domain DUF4112 PF13430.6 OAF98765.1 - 2.9e-32 111.0 0.2 3.8e-32 110.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HCV_core PF01542.18 OAF98765.1 - 0.046 14.1 0.2 0.79 10.2 0.0 2.3 1 1 1 2 2 2 0 Hepatitis C virus core protein DUF3425 PF11905.8 OAF98766.1 - 8.5e-16 58.1 0.0 2.8e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAF98766.1 - 0.26 11.4 7.1 0.37 10.9 7.1 1.2 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.25 OAF98767.1 - 8.5e-16 58.0 0.0 3.4e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAF98767.1 - 7.8e-08 32.4 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAF98767.1 - 8.9e-07 28.7 0.0 3.6e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAF98767.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAF98767.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 OAF98768.1 - 2.6e-36 125.3 22.9 2.6e-36 125.3 22.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF98768.1 - 5.6e-07 28.8 20.8 1.4e-06 27.5 19.8 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF98769.1 - 3.4e-36 124.9 51.7 1.1e-35 123.2 51.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAF98769.1 - 4.3e-12 45.3 15.6 4.3e-12 45.3 15.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4730 PF15873.5 OAF98769.1 - 0.043 14.1 0.9 0.043 14.1 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) p450 PF00067.22 OAF98770.1 - 2.7e-26 92.4 0.2 4.6e-26 91.6 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.22 OAF98771.1 - 2.6e-19 69.3 0.0 3.9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MINDY_DUB PF04424.13 OAF98772.1 - 0.034 14.2 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 MINDY deubiquitinase 5TM-5TMR_LYT PF07694.12 OAF98772.1 - 0.041 13.4 11.2 0.097 12.2 0.3 2.5 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Syndecan PF01034.20 OAF98772.1 - 0.53 10.2 0.0 0.53 10.2 0.0 3.3 4 1 1 5 5 5 0 Syndecan domain MARVEL PF01284.23 OAF98772.1 - 0.59 10.2 12.2 0.26 11.3 3.5 2.4 1 1 1 2 2 2 0 Membrane-associating domain Abhydrolase_6 PF12697.7 OAF98776.1 - 1.7e-11 45.2 1.4 2.6e-11 44.5 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAF98776.1 - 7.8e-11 41.7 0.1 2.7e-10 39.9 0.0 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAF98776.1 - 1.5e-06 28.2 0.1 2.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OAF98776.1 - 3.7e-06 26.8 0.2 7.5e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OAF98776.1 - 0.14 11.9 0.0 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Astacin PF01400.24 OAF98777.1 - 3.9e-22 78.8 0.0 3.6e-21 75.7 0.0 2.0 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) DUF4215 PF13948.6 OAF98777.1 - 2.6e-05 24.6 10.3 2.6e-05 24.6 10.3 3.3 5 0 0 5 5 5 1 Domain of unknown function (DUF4215) Peptidase_M10 PF00413.24 OAF98777.1 - 0.024 14.5 0.5 0.44 10.4 0.2 2.2 2 0 0 2 2 2 0 Matrixin Peptidase_M66 PF10462.9 OAF98777.1 - 0.048 12.6 0.1 0.071 12.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 OAF98777.1 - 0.075 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 OAF98777.1 - 0.15 10.6 0.4 0.27 9.8 0.4 1.3 1 0 0 1 1 1 0 Putative peptidase family Glyco_transf_15 PF01793.16 OAF98779.1 - 8.1e-93 311.2 2.3 1.5e-92 310.3 2.3 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EcpB_C PF18649.1 OAF98780.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 EcpB C-terminal domain F-box-like_2 PF13013.6 OAF98782.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 F-box-like domain MARVEL PF01284.23 OAF98783.1 - 0.00055 20.0 22.3 0.00087 19.3 22.3 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF3955 PF13127.6 OAF98783.1 - 0.13 12.1 0.7 0.13 12.1 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) CFEM PF05730.11 OAF98784.1 - 1.2e-07 31.7 1.5 1.9e-07 31.1 1.5 1.4 1 1 0 1 1 1 1 CFEM domain F-box-like PF12937.7 OAF98786.1 - 5e-09 35.9 0.2 1.4e-08 34.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAF98786.1 - 0.00081 19.2 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAF98786.1 - 0.0025 17.7 0.2 0.005 16.7 0.2 1.5 1 0 0 1 1 1 1 F-box CFEM PF05730.11 OAF98787.1 - 0.00046 20.2 4.5 0.00085 19.4 4.5 1.4 1 0 0 1 1 1 1 CFEM domain MTP18 PF10558.9 OAF98787.1 - 0.12 12.3 2.2 0.18 11.8 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) peroxidase PF00141.23 OAF98789.1 - 9.6e-81 270.8 0.0 2.7e-44 151.6 0.0 2.4 2 1 0 2 2 2 2 Peroxidase YebO PF13974.6 OAF98790.1 - 0.22 11.7 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 YebO-like protein Bestrophin PF01062.21 OAF98791.1 - 5e-30 104.9 0.0 7.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sugar_tr PF00083.24 OAF98792.1 - 2e-87 294.0 17.9 2.5e-87 293.7 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF98792.1 - 9.8e-27 93.8 51.8 3.5e-24 85.4 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OAF98793.1 - 2e-44 152.0 0.0 2.9e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF98793.1 - 1.6e-29 103.0 0.0 2.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAF98793.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAF98793.1 - 0.054 13.4 1.4 0.11 12.4 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF1472 PF07339.12 OAF98793.1 - 0.07 13.7 0.1 0.34 11.5 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1472) Ribonuc_L-PSP PF01042.21 OAF98794.1 - 5.8e-41 139.3 0.2 6.5e-41 139.1 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pribosyltran PF00156.27 OAF98795.1 - 5.5e-15 55.2 0.0 8.9e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAF98795.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase AIRS_C PF02769.22 OAF98796.1 - 2e-38 131.9 0.0 4.7e-38 130.8 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 OAF98796.1 - 1.2e-12 48.3 0.7 3.6e-12 46.8 0.7 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.26 OAF98796.1 - 2.5e-12 46.8 0.1 6.8e-12 45.4 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAF98796.1 - 0.00051 20.4 0.0 0.0025 18.2 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal AAA PF00004.29 OAF98797.1 - 1.1e-18 68.0 0.0 2.2e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAF98797.1 - 0.00016 22.0 5.1 0.0033 17.7 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 OAF98797.1 - 0.00027 20.7 0.0 0.00064 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAF98797.1 - 0.00047 20.6 0.1 0.0031 17.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OAF98797.1 - 0.0026 18.3 0.0 0.021 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAF98797.1 - 0.0069 16.4 0.1 0.024 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 OAF98797.1 - 0.009 16.4 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAF98797.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 OAF98797.1 - 0.018 15.2 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAF98797.1 - 0.023 14.6 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 OAF98797.1 - 0.047 12.9 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 OAF98797.1 - 0.089 12.5 0.1 0.55 9.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain cNMPbd_u2 PF16643.5 OAF98801.1 - 3.5e-06 27.6 0.4 3.5e-06 27.6 0.4 2.1 3 0 0 3 3 3 1 Unstructured region on cNMP-binding protein NmrA PF05368.13 OAF98802.1 - 1.9e-12 47.3 0.0 1.1e-08 34.9 0.0 2.0 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 OAF98802.1 - 0.0046 16.9 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 OAF98802.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GCHY-1 PF02649.14 OAF98806.1 - 0.22 11.0 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 DUF2975 PF11188.8 OAF98808.1 - 0.06 13.2 2.2 0.095 12.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) adh_short PF00106.25 OAF98809.1 - 2.3e-30 105.5 0.5 3.1e-30 105.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF98809.1 - 1.9e-23 83.2 0.0 2.7e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAF98809.1 - 5.9e-15 55.6 0.1 7.8e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAF98809.1 - 2.6e-06 26.8 0.1 3.3e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAF98809.1 - 0.0003 20.4 0.1 0.00038 20.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAF98809.1 - 0.017 15.0 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 OAF98809.1 - 0.053 13.6 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mucin PF01456.17 OAF98810.1 - 1.3 9.1 6.1 2 8.4 6.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Cys_Met_Meta_PP PF01053.20 OAF98811.1 - 7.4e-64 215.7 0.0 2e-63 214.3 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAF98811.1 - 0.0075 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAF98811.1 - 0.06 12.5 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Pro_isomerase PF00160.21 OAF98812.1 - 1.3e-42 145.8 0.2 1.9e-42 145.2 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 OAF98813.1 - 1e-46 158.1 0.2 1.4e-46 157.6 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAF98813.1 - 0.00057 19.0 0.0 0.0008 18.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 OAF98813.1 - 0.18 11.6 0.1 0.41 10.5 0.1 1.6 1 1 0 1 1 1 0 VHS domain DUF267 PF03268.14 OAF98816.1 - 0.03 13.2 2.0 0.045 12.6 0.0 2.1 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF267 ADH_N PF08240.12 OAF98817.1 - 1.9e-24 85.7 3.3 3.3e-24 84.8 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAF98817.1 - 2.9e-19 69.3 0.0 4.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAF98817.1 - 0.00012 23.2 0.0 0.00017 22.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAF98817.1 - 0.0013 18.1 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAF98817.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PA28_beta PF02252.18 OAF98817.1 - 0.047 13.4 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit GFO_IDH_MocA PF01408.22 OAF98817.1 - 0.085 13.7 0.0 0.25 12.2 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Tannase PF07519.11 OAF98819.1 - 3.2e-29 102.2 0.3 4.3e-13 49.0 0.5 2.8 2 1 0 2 2 2 2 Tannase and feruloyl esterase Polysacc_deac_1 PF01522.21 OAF98821.1 - 0.019 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase adh_short PF00106.25 OAF98822.1 - 0.00068 19.2 0.0 0.0015 18.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase F-box-like_2 PF13013.6 OAF98824.1 - 0.00014 21.8 0.1 0.001 19.0 0.1 2.2 1 1 0 1 1 1 1 F-box-like domain Amidohydro_1 PF01979.20 OAF98826.1 - 3.6e-19 69.3 1.6 1.2e-16 60.9 0.5 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OAF98826.1 - 9.1e-15 55.1 8.0 4.1e-11 43.0 2.5 2.3 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 OAF98827.1 - 1.2e-08 34.2 0.1 2.3e-08 33.3 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF98827.1 - 5.4e-07 29.6 11.3 9.1e-07 28.9 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L14 PF00238.19 OAF98832.1 - 6e-33 113.5 0.0 7.2e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e F-box-like PF12937.7 OAF98834.1 - 1.1e-05 25.2 0.2 4.8e-05 23.2 0.1 2.2 2 1 0 2 2 2 1 F-box-like PRO8NT PF08082.11 OAF98834.1 - 0.13 12.2 0.1 1 9.3 0.1 2.0 2 0 0 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain F-box PF00646.33 OAF98834.1 - 1.5 8.8 5.4 1.6 8.7 0.1 2.7 3 0 0 3 3 3 0 F-box domain DUF1907 PF08925.11 OAF98835.1 - 4.1e-108 361.1 0.0 4.7e-108 360.9 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) MFS_1 PF07690.16 OAF98836.1 - 8.6e-46 156.5 56.8 3.6e-45 154.4 40.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF98836.1 - 1.6e-11 43.8 5.8 1.6e-11 43.8 5.8 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.18 OAF98838.1 - 6.1e-09 35.9 7.4 1.1e-08 35.0 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAF98838.1 - 1.6e-06 27.2 0.1 2.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp PF00026.23 OAF98839.1 - 8.9e-08 31.9 0.2 1.2e-07 31.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 OAF98839.1 - 0.0076 15.6 3.3 0.015 14.7 3.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 OAF98839.1 - 0.39 9.5 3.2 0.6 8.9 3.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein PTP_tm PF18861.1 OAF98839.1 - 1.1 9.2 3.2 2.1 8.3 3.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SNF2_N PF00176.23 OAF98841.1 - 3.6e-70 236.4 0.0 4.7e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAF98841.1 - 5.2e-21 74.4 0.1 1.4e-20 73.0 0.1 1.8 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAF98841.1 - 1.5e-14 54.2 0.0 3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAF98841.1 - 2.1e-05 24.6 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 OAF98841.1 - 7.7e-05 22.5 9.2 0.00014 21.6 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAF98841.1 - 0.00022 21.0 4.5 0.00046 20.0 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAF98841.1 - 0.00022 21.0 7.2 0.00038 20.3 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAF98841.1 - 0.00077 19.7 9.2 0.0017 18.7 9.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAF98841.1 - 0.0039 17.2 7.7 0.008 16.2 7.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAF98841.1 - 0.049 13.6 8.5 0.26 11.3 8.8 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Endonuclease_7 PF02945.15 OAF98841.1 - 1.4 8.9 4.7 22 5.0 0.8 2.6 1 1 1 2 2 2 0 Recombination endonuclease VII Prok-RING_4 PF14447.6 OAF98841.1 - 3.1 7.7 9.3 19 5.2 9.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAF98841.1 - 9.3 6.5 7.6 19 5.5 7.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.19 OAF98842.1 - 4e-55 187.2 0.0 7.6e-55 186.2 0.0 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase DNA_pol_delta_4 PF04081.13 OAF98842.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 Phos_pyr_kin PF08543.12 OAF98843.1 - 0.0022 17.4 1.0 0.0027 17.2 1.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ctr PF04145.15 OAF98844.1 - 6e-32 111.3 0.0 8.2e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family NUDIX PF00293.28 OAF98846.1 - 4e-07 30.1 0.0 8.9e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.25 OAF98847.1 - 1.8e-128 428.4 3.4 2.3e-128 428.0 3.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OAF98847.1 - 4.8e-18 65.4 0.1 1.2e-08 35.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 OAF98847.1 - 1.1e-07 31.2 0.7 2e-06 27.1 0.4 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 OAF98847.1 - 6.3e-07 29.1 5.4 0.01 15.2 6.3 3.2 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 OAF98847.1 - 0.00049 19.6 1.2 0.0024 17.4 1.2 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein YpsA PF06908.11 OAF98847.1 - 0.0016 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 YspA SLOG family PK PF00224.21 OAF98847.1 - 0.013 14.4 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Aldolase PF01081.19 OAF98847.1 - 0.027 13.9 0.6 0.15 11.5 0.1 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.14 OAF98847.1 - 0.03 13.6 0.2 0.065 12.5 0.2 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG RasGAP PF00616.19 OAF98848.1 - 2.9e-53 180.7 0.0 5.8e-53 179.7 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAF98848.1 - 1.8e-48 164.2 0.3 7.1e-48 162.2 0.3 2.2 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 OAF98848.1 - 5.4e-12 44.4 52.3 0.029 14.1 1.4 14.2 15 0 0 15 15 15 6 IQ calmodulin-binding motif CH PF00307.31 OAF98848.1 - 3.2e-11 43.4 0.0 1.1e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain TetR_C_6 PF13977.6 OAF98848.1 - 0.018 15.2 1.7 8.4 6.7 0.0 3.5 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Fzo_mitofusin PF04799.13 OAF98848.1 - 0.18 11.3 3.3 3.8 7.0 0.0 3.0 3 0 0 3 3 3 0 fzo-like conserved region HATPase_c PF02518.26 OAF98849.1 - 1.1e-24 87.1 0.0 1.9e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAF98849.1 - 1e-13 51.4 0.0 8.1e-11 42.1 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 OAF98849.1 - 7.8e-10 38.7 0.3 2.9e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HET PF06985.11 OAF98850.1 - 5.8e-25 88.3 0.7 2.9e-22 79.6 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Bud13 PF09736.9 OAF98851.1 - 0.18 12.2 0.1 0.89 9.9 0.0 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex zf-RING_UBOX PF13445.6 OAF98852.1 - 0.31 11.1 8.7 1.1 9.4 8.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 OAF98852.1 - 0.65 10.4 11.3 0.49 10.8 8.7 2.2 2 1 0 2 2 2 0 Ring finger domain GDPD PF03009.17 OAF98853.1 - 1.2e-18 67.8 0.0 1.6e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Oxysterol_BP PF01237.18 OAF98854.1 - 1.3e-91 307.2 0.2 5.5e-81 272.3 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Isochorismatase PF00857.20 OAF98855.1 - 8.7e-29 100.9 0.1 1.8e-28 99.9 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family COX5B PF01215.19 OAF98856.1 - 1.3e-56 189.8 0.0 1.8e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb CGI-121 PF08617.10 OAF98857.1 - 1.1e-47 162.1 0.0 1.3e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.18 OAF98859.1 - 2.1e-10 40.1 0.3 4e-10 39.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF98859.1 - 8.8e-06 25.8 11.7 1.5e-05 25.0 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.18 OAF98859.1 - 0.2 11.9 0.3 0.4 11.0 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Peptidase_S28 PF05577.12 OAF98860.1 - 5.3e-47 160.6 0.1 2.4e-46 158.5 0.2 1.8 2 0 0 2 2 2 1 Serine carboxypeptidase S28 HET PF06985.11 OAF98861.1 - 1.8e-24 86.7 0.0 3.7e-24 85.8 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2721 PF11026.8 OAF98863.1 - 0.017 15.0 1.8 0.019 14.8 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) CoA_binding_3 PF13727.6 OAF98863.1 - 0.039 14.0 1.8 0.042 13.9 1.8 1.0 1 0 0 1 1 1 0 CoA-binding domain ABC2_membrane_3 PF12698.7 OAF98863.1 - 0.45 9.6 5.1 0.55 9.3 5.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4131 PF13567.6 OAF98863.1 - 0.53 9.9 3.0 0.55 9.9 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) p450 PF00067.22 OAF98864.1 - 7e-07 28.3 0.0 0.00047 19.0 0.0 3.4 2 1 2 4 4 4 3 Cytochrome P450 FAD_binding_3 PF01494.19 OAF98865.1 - 1.5e-15 57.4 0.5 1.1e-13 51.2 0.5 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAF98865.1 - 1.1e-05 25.6 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAF98865.1 - 0.0031 16.8 0.0 0.012 14.8 0.0 2.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAF98865.1 - 0.0098 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAF98865.1 - 0.013 16.0 0.0 0.036 14.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAF98865.1 - 0.015 14.5 0.0 0.36 10.0 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAF98865.1 - 0.028 13.5 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 OAF98865.1 - 0.032 13.8 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 OAF98865.1 - 0.048 13.3 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 OAF98865.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Spermine_synth PF01564.17 OAF98865.1 - 0.11 11.8 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Spermine/spermidine synthase domain DUF202 PF02656.15 OAF98867.1 - 7.5e-21 74.3 0.5 7.5e-21 74.3 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Lactamase_B PF00753.27 OAF98868.1 - 2.3e-15 57.1 1.0 1.3e-14 54.7 1.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPMT PF05724.11 OAF98869.1 - 7.1e-29 101.0 0.0 1e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 OAF98869.1 - 1.9e-09 37.5 0.0 2.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAF98869.1 - 1.1e-08 35.6 0.0 1.8e-07 31.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAF98869.1 - 4e-08 33.9 0.0 6.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAF98869.1 - 6e-08 32.6 0.0 7.9e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAF98869.1 - 5.5e-07 30.2 0.0 2.3e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 OAF98869.1 - 0.0038 16.5 0.0 0.0079 15.4 0.0 1.5 2 0 0 2 2 2 1 N2227-like protein CheR PF01739.18 OAF98869.1 - 0.036 13.5 0.0 0.31 10.5 0.0 2.1 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 OAF98869.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Dynamin_M PF01031.20 OAF98870.1 - 1e-10 41.3 0.0 1.4e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region DUF3963 PF13124.6 OAF98870.1 - 0.06 13.3 2.3 0.59 10.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) Collagen PF01391.18 OAF98873.1 - 1.3e-37 127.3 149.5 2.3e-09 36.9 34.6 5.0 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) ADH_N PF08240.12 OAF98874.1 - 4.2e-29 100.6 1.7 8.6e-29 99.6 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAF98874.1 - 3.7e-20 72.2 0.4 3.7e-20 72.2 0.4 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAF98874.1 - 1.9e-10 40.6 1.8 5.2e-10 39.2 1.8 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAF98874.1 - 1.2e-05 26.4 0.3 3.9e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAF98874.1 - 6.9e-05 22.2 4.0 0.00027 20.3 4.0 2.0 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aegerolysin PF06355.13 OAF98875.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Aegerolysin Med3 PF11593.8 OAF98876.1 - 0.17 11.0 0.7 0.22 10.7 0.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Beta-lactamase PF00144.24 OAF98877.1 - 9.2e-19 67.8 0.0 1.3e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_88 PF07470.13 OAF98878.1 - 1.1e-14 54.3 0.1 1.6e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CDP-OH_P_transf PF01066.21 OAF98880.1 - 2.4e-15 57.0 0.1 2.4e-15 57.0 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Aspzincin_M35 PF14521.6 OAF98881.1 - 3.7e-37 128.1 6.6 3.7e-37 128.1 6.6 2.0 3 0 0 3 3 3 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 OAF98881.1 - 3.7e-31 108.3 22.6 8.8e-31 107.1 22.6 1.5 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 OAF98881.1 - 0.00039 20.1 1.6 0.00039 20.1 1.6 2.0 2 0 0 2 2 2 1 Putative peptidase family CARDB PF07705.11 OAF98881.1 - 0.022 15.0 0.4 0.022 15.0 0.4 2.6 2 2 0 2 2 2 0 CARDB GST_N_5 PF18485.1 OAF98881.1 - 0.051 13.9 0.1 0.15 12.5 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2235 PF09994.9 OAF98882.1 - 8.2e-83 278.1 0.0 1.1e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MFS_1 PF07690.16 OAF98883.1 - 1.5e-29 103.1 31.0 1.5e-29 103.1 31.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Aldolase_II PF00596.21 OAF98884.1 - 1.2e-46 159.0 0.0 1.4e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3602 PF12223.8 OAF98885.1 - 2.8e-21 75.9 11.5 6.9e-20 71.4 3.7 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Mito_carr PF00153.27 OAF98886.1 - 1e-45 153.6 7.9 4e-17 61.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_18 PF00704.28 OAF98887.1 - 2.4e-07 30.8 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1295 PF06966.12 OAF98888.1 - 1.1e-44 152.8 0.1 1.3e-44 152.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAF98888.1 - 3.2e-07 30.4 1.9 5.6e-06 26.4 0.1 2.8 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OAF98888.1 - 4.3e-05 23.9 0.0 9.7e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAF98888.1 - 0.098 13.1 0.2 0.45 10.9 0.2 2.2 1 1 0 1 1 1 0 Phospholipid methyltransferase FAD_binding_3 PF01494.19 OAF98891.1 - 8e-22 77.9 0.0 4e-21 75.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 OAF98891.1 - 0.00024 20.3 0.0 0.0024 17.0 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 OAF98891.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAF98891.1 - 0.066 12.4 0.0 0.44 9.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_15 PF00723.21 OAF98892.1 - 5.2e-96 322.1 0.2 6.5e-96 321.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 OAF98892.1 - 9.8e-34 115.1 1.2 2.2e-33 114.1 1.2 1.6 1 0 0 1 1 1 1 Starch binding domain MoaF PF10703.9 OAF98894.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 MoaF N-terminal domain HTH_54 PF18607.1 OAF98894.1 - 0.04 14.0 0.2 0.04 14.0 0.2 1.6 2 0 0 2 2 2 0 ParA helix turn helix domain CENP-H PF05837.12 OAF98894.1 - 0.62 10.5 8.4 0.78 10.2 5.8 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) AA_permease PF00324.21 OAF98895.1 - 3.5e-126 421.6 45.8 4.2e-126 421.4 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAF98895.1 - 4.2e-28 98.4 51.2 5.7e-28 97.9 51.2 1.1 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 OAF98895.1 - 0.098 13.2 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Pet100 DUF575 PF04746.12 OAF98895.1 - 1.4 9.2 3.3 8.4 6.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF575) HET PF06985.11 OAF98896.1 - 7.3e-29 101.0 0.6 8.3e-29 100.8 0.6 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MARVEL PF01284.23 OAF98897.1 - 0.0008 19.5 4.6 0.0043 17.1 3.9 2.2 1 1 0 1 1 1 1 Membrane-associating domain DUF4134 PF13572.6 OAF98897.1 - 0.13 12.6 5.3 1.9 8.8 0.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4134) DUF2207 PF09972.9 OAF98897.1 - 5.5 5.6 8.0 26 3.4 7.9 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.11 OAF98897.1 - 7.4 6.0 8.1 0.64 9.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) FtsL PF04999.13 OAF98897.1 - 7.9 6.6 14.8 0.89 9.6 0.1 3.8 3 1 1 4 4 4 0 Cell division protein FtsL Cytomega_UL20A PF05984.12 OAF98898.1 - 0.029 14.7 2.4 0.061 13.6 0.1 2.1 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein LRRNT_2 PF08263.12 OAF98898.1 - 0.13 12.6 0.6 0.13 12.6 0.6 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain TLP1_add_C PF18313.1 OAF98899.1 - 1.1e-26 92.6 0.2 1.1e-26 92.6 0.2 2.1 3 0 0 3 3 3 1 Thiolase-like protein type 1 additional C-terminal domain Sec10 PF07393.11 OAF98900.1 - 7.8e-195 649.4 0.0 9.9e-195 649.0 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.7 OAF98900.1 - 0.068 13.1 0.0 0.25 11.3 0.0 2.0 1 0 0 1 1 1 0 MarR family DUF2989 PF11207.8 OAF98900.1 - 0.088 12.6 0.1 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) Mod_r PF07200.13 OAF98900.1 - 0.19 11.8 3.6 2.1 8.5 0.1 3.4 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF2415 PF10313.9 OAF98901.1 - 0.13 12.2 0.1 0.38 10.7 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Ribosomal_60s PF00428.19 OAF98902.1 - 1.5e-25 89.5 9.4 1.8e-25 89.3 9.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 OAF98902.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain SPT2 PF08243.11 OAF98903.1 - 1.9e-06 28.4 11.8 1.9e-06 28.4 11.8 1.7 2 0 0 2 2 2 1 SPT2 chromatin protein Pkinase PF00069.25 OAF98905.1 - 1.5e-42 145.8 0.0 2.1e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF98905.1 - 3.8e-19 69.0 0.0 6.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAF98905.1 - 0.046 13.3 0.3 0.11 12.0 0.2 1.7 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OAF98905.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SOG2 PF10428.9 OAF98905.1 - 4.8 6.3 8.4 6.6 5.8 8.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Beta-lactamase PF00144.24 OAF98906.1 - 8.7e-28 97.5 0.0 2.6e-27 95.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase RNase_P_p30 PF01876.16 OAF98907.1 - 3.8e-58 196.5 0.1 7.8e-58 195.5 0.0 1.5 2 0 0 2 2 2 1 RNase P subunit p30 Abhydrolase_6 PF12697.7 OAF98907.1 - 0.012 16.3 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.25 OAF98908.1 - 1.1e-65 221.6 0.1 1.3e-65 221.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF98908.1 - 9.3e-17 61.2 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAF98908.1 - 6.4e-07 29.5 0.1 2.3e-05 24.5 0.1 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAF98908.1 - 0.00049 19.5 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAF98908.1 - 0.004 16.0 0.0 0.0073 15.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAF98908.1 - 0.018 14.4 0.3 0.043 13.2 0.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAF98908.1 - 0.022 14.4 0.2 0.056 13.0 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 OAF98909.1 - 4.1e-215 715.6 0.0 8.9e-214 711.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAF98909.1 - 3.2e-31 108.3 1.7 5.3e-31 107.6 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAF98909.1 - 1.3e-12 47.2 0.6 0.00027 19.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAF98909.1 - 1.6e-12 47.3 0.1 6.4e-09 35.6 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAF98909.1 - 0.00087 18.7 0.0 0.036 13.4 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Roughex PF06020.11 OAF98909.1 - 6.5 5.7 7.0 10 5.1 7.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Peroxidase_2 PF01328.17 OAF98910.1 - 5.6e-05 23.8 0.0 7.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 DUF1953 PF09196.10 OAF98911.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) HSP70 PF00012.20 OAF98912.1 - 3.5e-225 748.8 10.3 3.9e-225 748.6 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAF98912.1 - 1.5e-15 56.9 0.2 1.4e-14 53.7 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAF98912.1 - 0.00022 21.0 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain UQ_con PF00179.26 OAF98913.1 - 2.8e-26 91.9 0.0 3.3e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAF98913.1 - 1.7e-06 27.7 0.0 3.2e-06 26.9 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B UEV PF05743.13 OAF98913.1 - 0.0015 18.4 0.1 0.0019 18.0 0.1 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 OAF98913.1 - 0.075 13.3 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain RHINO PF15319.6 OAF98914.1 - 0.052 13.6 0.1 0.061 13.3 0.1 1.1 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein PWWP PF00855.17 OAF98916.1 - 1.5e-15 57.3 0.1 1.5e-15 57.3 0.1 2.8 2 1 1 3 3 3 1 PWWP domain Med26 PF08711.11 OAF98916.1 - 0.0079 16.2 0.1 0.023 14.7 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain GMC_oxred_N PF00732.19 OAF98918.1 - 7.8e-46 156.8 0.0 1.1e-45 156.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAF98918.1 - 2.9e-40 138.1 0.0 4.9e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAF98918.1 - 1.7e-05 24.1 4.1 0.011 14.8 2.3 2.8 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 OAF98918.1 - 0.00028 20.2 3.1 0.39 9.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAF98918.1 - 0.00077 19.1 4.1 0.034 13.7 2.5 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAF98918.1 - 0.0016 17.7 2.8 0.01 15.1 1.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAF98918.1 - 0.016 14.5 0.9 0.96 8.6 1.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 OAF98918.1 - 0.037 14.3 2.7 0.091 13.0 2.7 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAF98918.1 - 0.084 12.1 0.3 0.15 11.2 0.3 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAF98918.1 - 0.098 11.7 0.3 0.16 11.0 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OAF98918.1 - 1 8.7 2.9 3 7.1 2.6 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Abhydrolase_1 PF00561.20 OAF98919.1 - 1.3e-23 84.0 0.2 2.4e-21 76.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAF98919.1 - 1.7e-15 58.2 1.3 2e-15 58.0 1.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAF98919.1 - 1e-06 28.2 0.0 6.4e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAF98919.1 - 0.078 12.8 0.0 7.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3807 PF12720.7 OAF98920.1 - 2.9e-37 128.7 19.0 4e-37 128.2 19.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) FAM199X PF15814.5 OAF98920.1 - 0.004 16.2 7.2 0.005 15.9 7.2 1.1 1 0 0 1 1 1 1 Protein family FAM199X PPP4R2 PF09184.11 OAF98920.1 - 0.49 9.9 11.9 0.58 9.7 11.9 1.1 1 0 0 1 1 1 0 PPP4R2 Coilin_N PF15862.5 OAF98920.1 - 0.56 10.0 9.6 1.4 8.7 9.6 1.7 1 1 0 1 1 1 0 Coilin N-terminus Endostatin PF06482.11 OAF98920.1 - 0.65 9.4 7.4 0.8 9.1 7.4 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 OAF98920.1 - 1.4 8.7 13.5 1.7 8.4 13.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 OAF98920.1 - 1.4 8.3 11.6 2.1 7.7 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 OAF98920.1 - 1.6 6.9 14.7 1.8 6.7 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 OAF98920.1 - 1.9 9.0 12.4 2.8 8.5 12.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3435 PF11917.8 OAF98920.1 - 2.2 7.1 12.2 3.1 6.6 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Neur_chan_memb PF02932.16 OAF98920.1 - 2.3 8.2 5.0 2.5 8.1 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S30 PF01577.16 OAF98920.1 - 2.8 7.5 13.3 4.2 6.9 13.3 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease PBP_sp32 PF07222.12 OAF98920.1 - 4.4 6.7 11.2 6.7 6.1 11.2 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ALMT PF11744.8 OAF98920.1 - 4.6 6.0 4.8 4.7 5.9 4.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Fasciclin PF02469.22 OAF98921.1 - 2e-05 24.8 0.0 4.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain GNAT_acetyltr_2 PF13718.6 OAF98923.1 - 2.8e-98 327.9 0.0 4.9e-98 327.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OAF98923.1 - 2.5e-90 302.3 0.0 4.2e-90 301.6 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 OAF98923.1 - 8.1e-66 221.2 0.0 2.6e-65 219.6 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 OAF98923.1 - 7.9e-34 115.5 0.2 2.2e-33 114.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 OAF98923.1 - 7.4e-05 22.5 0.1 0.014 15.2 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OAF98923.1 - 0.0019 18.5 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 OAF98923.1 - 0.018 15.3 0.0 0.076 13.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family AAA_19 PF13245.6 OAF98923.1 - 0.12 12.7 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain HET PF06985.11 OAF98924.1 - 1.5e-38 132.4 0.0 2.1e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAF98925.1 - 8.7e-38 129.9 0.0 1.3e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SUA5 PF03481.13 OAF98925.1 - 0.038 14.6 0.0 0.068 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding SUR7 PF06687.12 OAF98926.1 - 2.7e-34 118.7 3.7 3.1e-34 118.5 3.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 OAF98926.1 - 0.00086 19.3 8.1 0.00086 19.3 8.1 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Stevor PF17410.2 OAF98926.1 - 0.038 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4481 PF14800.6 OAF98926.1 - 0.095 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) MpPF26 PF07666.11 OAF98926.1 - 0.74 9.9 5.3 1.7 8.8 5.3 1.5 1 0 0 1 1 1 0 M penetrans paralogue family 26 DUF4231 PF14015.6 OAF98926.1 - 2 8.9 8.8 18 5.8 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4805 PF16063.5 OAF98927.1 - 3.3 7.0 9.2 12 5.1 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) Macoilin PF09726.9 OAF98928.1 - 5.3 5.5 9.7 9.5 4.6 9.7 1.3 1 0 0 1 1 1 0 Macoilin family EF-hand_1 PF00036.32 OAF98929.1 - 1.3e-25 87.0 10.6 4e-07 29.1 0.1 5.7 5 1 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 OAF98929.1 - 9.1e-23 80.5 4.0 6.6e-11 42.5 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OAF98929.1 - 5.4e-21 72.7 7.9 6.8e-05 22.5 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OAF98929.1 - 6.1e-21 74.0 6.9 1.2e-11 44.3 0.0 4.7 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 OAF98929.1 - 6.3e-17 60.2 9.7 0.0005 19.4 0.1 4.7 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OAF98929.1 - 0.0086 16.4 0.2 2.2 8.6 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 OAF98929.1 - 0.16 11.9 1.1 4.6 7.3 0.0 2.8 1 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand HET PF06985.11 OAF98931.1 - 7.9e-26 91.2 0.0 1.3e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OppC_N PF12911.7 OAF98931.1 - 0.043 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SRF-TF PF00319.18 OAF98932.1 - 3.7e-24 83.9 0.2 5.5e-24 83.4 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Presenilin PF01080.17 OAF98932.1 - 2.9 6.5 3.7 3.9 6.1 3.7 1.3 1 0 0 1 1 1 0 Presenilin DUF1996 PF09362.10 OAF98934.1 - 1.1e-70 238.2 0.0 1.3e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Abhydrolase_3 PF07859.13 OAF98935.1 - 5.2e-13 49.3 0.0 6.9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAF98935.1 - 2.1e-05 23.6 0.0 2.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 OAF98935.1 - 4.3e-05 22.6 0.0 0.0037 16.2 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 OAF98935.1 - 8.3e-05 22.2 0.0 0.022 14.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 OAF98935.1 - 0.0011 17.8 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 OAF98935.1 - 0.0044 16.3 0.0 0.1 11.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OAF98935.1 - 0.0053 15.8 0.0 0.0068 15.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Say1_Mug180 PF10340.9 OAF98935.1 - 0.047 12.5 0.0 2.8 6.7 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase Esterase PF00756.20 OAF98935.1 - 0.12 12.0 0.0 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Putative esterase DUF1708 PF08101.11 OAF98936.1 - 2.6e-171 570.5 0.0 3.9e-171 570.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Rbsn PF11464.8 OAF98937.1 - 0.22 11.3 2.5 1.8 8.3 0.3 2.7 1 1 2 3 3 3 0 Rabenosyn Rab binding domain CDH-cyt PF16010.5 OAF98938.1 - 2e-51 174.3 5.4 4e-51 173.3 5.4 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase p450 PF00067.22 OAF98939.1 - 1.1e-95 321.1 0.0 1.3e-95 320.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2 PF00152.20 OAF98940.1 - 1.2e-73 247.9 0.0 1.8e-73 247.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAF98940.1 - 3.4e-15 55.8 0.0 4.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 OAF98940.1 - 2.9e-05 23.9 0.0 6.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain I_LWEQ PF01608.17 OAF98940.1 - 0.022 15.0 0.9 0.046 14.0 0.9 1.5 1 0 0 1 1 1 0 I/LWEQ domain tRNA-synt_2d PF01409.20 OAF98940.1 - 0.027 14.0 0.1 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) MCM_N PF14551.6 OAF98940.1 - 0.079 13.6 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 MCM N-terminal domain Hid1 PF12722.7 OAF98940.1 - 0.67 8.0 3.4 0.96 7.5 3.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Snurportin1 PF11538.8 OAF98940.1 - 2.6 8.3 8.9 5.7 7.2 8.9 1.6 1 0 0 1 1 1 0 Snurportin1 Questin_oxidase PF14027.6 OAF98941.1 - 1.5e-97 327.2 0.4 1.9e-97 326.9 0.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like Tubulin PF00091.25 OAF98942.1 - 4.1e-65 219.7 0.0 5.5e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAF98942.1 - 3.7e-43 146.7 0.0 5.6e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAF98942.1 - 0.0036 17.0 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.18 OAF98943.1 - 7.8e-23 81.1 2.2 1.2e-22 80.5 2.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 OAF98943.1 - 4.8e-05 22.7 0.1 0.00013 21.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OAF98943.1 - 0.00034 20.0 0.4 0.00083 18.7 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAF98943.1 - 0.0014 18.4 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAF98943.1 - 0.03 14.8 0.3 0.07 13.6 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF5531 PF17671.1 OAF98944.1 - 0.047 13.6 0.4 0.079 12.8 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5531) DUF4081 PF13312.6 OAF98945.1 - 0.0023 18.1 0.4 0.0059 16.8 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4081) SMP PF04927.12 OAF98945.1 - 0.0028 18.1 0.7 0.0028 18.1 0.7 2.5 2 1 0 2 2 2 1 Seed maturation protein EcoEI_R_C PF08463.10 OAF98945.1 - 0.0035 17.5 0.8 0.89 9.6 0.1 2.5 2 1 0 2 2 2 2 EcoEI R protein C-terminal DUF4088 PF13317.6 OAF98945.1 - 0.059 12.9 0.1 0.7 9.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4088) LRR_6 PF13516.6 OAF98946.1 - 5.7e-12 44.7 4.3 0.01 15.8 0.0 6.7 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 OAF98946.1 - 0.0031 17.9 10.4 6.4 7.3 0.0 5.4 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAF98946.1 - 0.013 15.3 9.4 2.5 7.9 0.1 4.6 4 1 0 4 4 4 0 Leucine rich repeat Radial_spoke PF04712.12 OAF98946.1 - 0.36 9.7 11.5 0.99 8.3 0.0 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein Roughex PF06020.11 OAF98946.1 - 5.9 5.9 11.2 8.8 5.3 11.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein NOA36 PF06524.12 OAF98946.1 - 7.9 5.7 9.4 11 5.2 9.4 1.3 1 0 0 1 1 1 0 NOA36 protein COX17 PF05051.13 OAF98947.1 - 1.2e-20 73.5 6.6 1.5e-20 73.3 6.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 OAF98947.1 - 0.49 10.7 5.0 1.1 9.6 5.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Alg6_Alg8 PF03155.15 OAF98948.1 - 1.4e-123 413.4 26.0 3.7e-79 266.9 12.5 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.22 OAF98949.1 - 2e-42 142.9 0.0 5.9e-20 70.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAF98949.1 - 0.00012 22.1 0.0 0.83 9.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAF98949.1 - 0.062 13.3 0.0 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 OAF98949.1 - 0.12 12.5 1.6 6.7 6.9 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 HLH PF00010.26 OAF98952.1 - 3.9e-15 55.5 0.3 9.3e-15 54.3 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HECT_2 PF09814.9 OAF98956.1 - 6e-90 301.8 0.0 7e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding 3Beta_HSD PF01073.19 OAF98957.1 - 9.3e-62 208.6 0.0 1.1e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAF98957.1 - 1.3e-30 106.7 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAF98957.1 - 1.2e-21 77.5 0.0 7.7e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAF98957.1 - 8.1e-14 51.4 0.1 6.1e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAF98957.1 - 3e-11 42.9 0.0 4.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAF98957.1 - 5.6e-09 35.5 0.0 2.5e-08 33.4 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAF98957.1 - 6.1e-09 36.0 0.0 9.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAF98957.1 - 3.5e-07 30.3 0.3 2.5e-05 24.3 0.3 2.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 OAF98957.1 - 2e-06 27.5 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAF98957.1 - 0.0037 17.5 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAF98957.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain UQ_con PF00179.26 OAF98958.1 - 3.8e-43 146.5 0.0 1.3e-29 102.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAF98958.1 - 0.00058 19.6 0.0 0.034 13.8 0.0 2.6 2 1 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 OAF98958.1 - 0.066 13.5 0.0 6.5 7.1 0.0 2.6 2 0 0 2 2 2 0 RWD domain UEV PF05743.13 OAF98958.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 UEV domain Sybindin PF04099.12 OAF98959.1 - 6e-41 139.7 0.0 7e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAF98959.1 - 1.2e-09 38.4 0.1 1.6e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 OAF98960.1 - 3.9e-23 82.1 0.1 1e-22 80.8 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OAF98960.1 - 5.2e-09 36.6 0.1 7.3e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 OAF98960.1 - 8.9e-06 25.7 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 OAF98960.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.3 3 0 0 3 3 3 0 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 OAF98961.1 - 2.5e-12 46.2 1.3 4.3e-12 45.5 1.3 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal LCIB_C_CA PF18599.1 OAF98961.1 - 0.08 12.2 0.4 1.1 8.5 0.1 2.0 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF1387 PF07139.11 OAF98961.1 - 3.7 7.2 8.0 1.2 8.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) zf-C2H2 PF00096.26 OAF98962.1 - 0.0026 18.1 5.7 0.0026 18.1 5.7 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type C1_4 PF07975.12 OAF98962.1 - 0.11 12.8 0.3 0.27 11.5 0.3 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_4 PF13894.6 OAF98962.1 - 0.2 12.6 14.2 0.14 13.0 4.9 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_1 PF07690.16 OAF98963.1 - 4.3e-14 52.2 26.9 1.4e-13 50.5 27.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF98963.1 - 4.8e-06 25.7 2.1 4.8e-06 25.7 2.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Scm3 PF10384.9 OAF98963.1 - 0.11 12.2 0.8 0.21 11.4 0.8 1.3 1 0 0 1 1 1 0 Centromere protein Scm3 SnoaL PF07366.12 OAF98965.1 - 0.0047 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Scm3 PF10384.9 OAF98966.1 - 7.9e-10 38.3 0.1 7.9e-10 38.3 0.1 2.4 2 0 0 2 2 2 1 Centromere protein Scm3 zf-C2H2 PF00096.26 OAF98966.1 - 0.028 14.9 0.6 0.065 13.7 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type APG6 PF04111.12 OAF98967.1 - 2e-66 223.3 0.0 2.9e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OAF98967.1 - 3.5e-31 108.5 5.0 5.6e-31 107.8 5.0 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 OAF98967.1 - 0.0062 17.1 0.3 0.012 16.2 0.3 1.5 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2968 PF11180.8 OAF98967.1 - 0.12 11.9 5.3 0.27 10.9 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) F-box-like PF12937.7 OAF98968.1 - 0.0005 19.9 0.0 0.031 14.2 0.0 3.0 2 1 0 2 2 2 1 F-box-like DUF3961 PF13106.6 OAF98968.1 - 0.036 13.7 0.1 0.082 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) FMN_red PF03358.15 OAF98969.1 - 2.7e-08 33.7 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OAF98969.1 - 6.7e-07 29.2 0.0 8.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 OAF98969.1 - 0.00025 21.3 0.2 0.0006 20.0 0.2 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 OAF98969.1 - 0.0027 17.9 0.0 0.53 10.5 0.0 2.2 1 1 1 2 2 2 2 Flavodoxin domain DHHA2 PF02833.14 OAF98970.1 - 2.2e-15 57.1 0.1 4.9e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 OAF98970.1 - 6e-10 39.3 0.0 9.6e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 DHH family Glyco_hydro_114 PF03537.13 OAF98971.1 - 7.4e-75 251.2 0.0 8.5e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 PPR_2 PF13041.6 OAF98972.1 - 1.5e-09 37.9 0.7 0.0032 17.6 0.1 4.4 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 OAF98972.1 - 0.01 16.1 3.3 1.4 9.4 0.1 4.6 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 OAF98972.1 - 0.077 13.1 0.0 5.4 7.2 0.0 2.9 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF2076 PF09849.9 OAF98973.1 - 9.8 6.1 11.8 13 5.7 11.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.25 OAF98974.1 - 2.2e-53 181.3 0.0 3.2e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF98974.1 - 6.8e-32 110.8 0.0 9.9e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAF98974.1 - 0.00015 20.7 0.0 0.00034 19.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAF98974.1 - 0.003 16.9 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAF98974.1 - 0.0032 16.5 0.0 0.079 11.9 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAF98974.1 - 0.03 14.2 0.1 0.3 11.0 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family RRN3 PF05327.11 OAF98975.1 - 1.4e-178 595.0 0.0 1.4e-178 595.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 OAF98975.1 - 0.016 15.1 12.1 0.25 11.2 2.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region RecO_C PF02565.15 OAF98975.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Recombination protein O C terminal Pro_isomerase PF00160.21 OAF98976.1 - 2.5e-49 167.6 0.8 2.8e-49 167.4 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.6 OAF98977.1 - 1.2e-12 47.9 6.9 1.8e-12 47.4 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAF98977.1 - 3.7e-09 36.1 0.7 6.2e-09 35.4 0.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAF98977.1 - 7.6e-09 35.3 4.3 1.2e-08 34.7 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAF98977.1 - 8.7e-09 35.1 6.9 1.4e-08 34.5 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAF98977.1 - 1.7e-06 28.2 9.8 1.3e-05 25.4 9.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAF98977.1 - 1.8e-06 27.8 4.4 2.7e-06 27.2 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAF98977.1 - 2.8e-05 24.0 1.0 2.8e-05 24.0 1.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAF98977.1 - 0.00048 19.9 3.0 0.0008 19.2 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAF98977.1 - 0.0015 18.6 3.4 0.0033 17.5 3.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OAF98977.1 - 0.031 13.9 4.5 0.054 13.1 4.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OAF98977.1 - 0.053 13.4 6.2 0.097 12.6 6.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 OAF98977.1 - 0.082 13.1 4.9 0.17 12.1 4.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING OAD_gamma PF04277.13 OAF98977.1 - 0.088 13.4 2.0 0.35 11.5 0.0 2.7 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-RING_4 PF14570.6 OAF98977.1 - 0.098 12.5 6.5 0.16 11.8 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OAF98977.1 - 0.12 12.3 5.1 0.25 11.3 5.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 OAF98977.1 - 0.2 11.8 3.7 0.42 10.8 3.7 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 OAF98977.1 - 0.31 11.2 3.5 0.85 9.8 3.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 OAF98977.1 - 1.8 8.7 5.5 3.9 7.6 5.5 1.6 1 0 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 OAF98977.1 - 3.2 7.7 8.6 0.11 12.5 1.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DHDPS PF00701.22 OAF98982.1 - 7.6e-36 123.3 0.0 9.9e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Toxin_ToxA PF11584.8 OAF98982.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA TPR_1 PF00515.28 OAF98983.1 - 1.2e-20 72.3 2.4 1.4e-07 31.0 0.0 5.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAF98983.1 - 2.1e-18 64.9 4.6 3.8e-06 26.6 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAF98983.1 - 2.7e-15 55.7 3.3 1.1e-07 31.4 0.0 5.1 4 2 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 OAF98983.1 - 2e-14 54.0 6.1 1.8e-06 28.5 0.2 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAF98983.1 - 4.6e-12 45.7 10.5 2.1e-05 25.0 0.1 5.5 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAF98983.1 - 5.6e-10 39.6 5.0 0.0015 19.0 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAF98983.1 - 1.1e-09 37.7 1.0 0.0015 18.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAF98983.1 - 1.5e-09 37.2 1.0 0.09 12.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAF98983.1 - 3.2e-08 33.4 1.5 0.22 12.0 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAF98983.1 - 7.7e-08 32.4 1.7 0.0015 18.6 0.1 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAF98983.1 - 1.3e-07 31.8 5.1 0.00021 21.5 0.2 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 OAF98983.1 - 1.5e-07 31.6 0.2 0.034 14.5 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAF98983.1 - 4.9e-05 23.7 3.6 6.2 7.7 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAF98983.1 - 5.2e-05 23.4 2.5 0.003 17.7 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAF98983.1 - 0.0041 16.4 1.4 1 8.5 0.6 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 OAF98983.1 - 0.012 15.6 0.0 1 9.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 OAF98983.1 - 0.038 14.0 0.0 38 4.4 0.0 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain NatB_MDM20 PF09797.9 OAF98983.1 - 0.099 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_10 PF13374.6 OAF98983.1 - 0.15 12.0 6.0 4.2 7.4 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 OAF98984.1 - 1.5e-36 124.0 0.3 2.1e-20 72.3 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAF98984.1 - 9.4e-05 22.2 0.0 0.00045 20.0 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OAF98984.1 - 0.00059 19.4 0.0 0.5 10.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 OAF98984.1 - 0.073 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAF98984.1 - 0.082 13.0 0.1 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif DUF3729 PF12526.8 OAF98984.1 - 2.3 9.8 8.5 0.65 11.6 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Abhydrolase_4 PF08386.10 OAF98985.1 - 2.9e-24 85.2 0.0 6.3e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 OAF98985.1 - 6.9e-19 68.5 0.1 4.1e-08 33.2 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold RRM_1 PF00076.22 OAF98986.1 - 4.3e-12 45.7 0.1 5.9e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyrophosphatase PF00719.19 OAF98990.1 - 2.9e-59 199.5 0.2 3.7e-59 199.1 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF2541 PF10807.8 OAF98990.1 - 0.13 12.4 0.0 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2541) MRP_L53 PF10780.9 OAF98991.1 - 7.3e-24 83.7 0.3 1e-23 83.3 0.3 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 OAF98992.1 - 4.1e-17 61.9 1.5 4.1e-17 61.9 1.5 2.3 3 0 0 3 3 3 1 Sec20 Lebercilin PF15619.6 OAF98992.1 - 0.024 14.3 1.4 0.024 14.3 1.4 3.9 4 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease MFS_1 PF07690.16 OAF98993.1 - 1e-50 172.7 22.8 1e-50 172.7 22.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF98993.1 - 1.4e-14 53.9 12.7 1.4e-14 53.9 12.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAF98993.1 - 0.0019 16.6 7.4 0.016 13.5 5.1 2.7 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF1931 PF09123.11 OAF98993.1 - 0.16 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) GATase PF00117.28 OAF98994.1 - 3.2e-07 30.3 0.0 4.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OAF98994.1 - 0.078 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NmrA PF05368.13 OAF98995.1 - 2.1e-22 79.9 0.1 2.9e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAF98995.1 - 1.7e-11 44.4 0.0 2.5e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OAF98995.1 - 0.002 18.2 0.2 0.0038 17.3 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 OAF98995.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAF98995.1 - 0.026 14.0 0.5 0.42 10.0 0.5 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 OAF98996.1 - 0.00011 22.3 6.4 0.0003 20.9 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37 PF08561.10 OAF98998.1 - 7.7e-44 149.1 0.0 1.3e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF2417 PF10329.9 OAF98999.1 - 9.2e-84 280.5 0.9 1.3e-83 280.1 0.9 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.7 OAF99000.1 - 2.1e-20 74.3 2.1 3.4e-20 73.6 2.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAF99000.1 - 7.2e-05 22.6 0.1 0.00028 20.6 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAF99000.1 - 7.5e-05 22.1 0.1 0.0001 21.7 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 OAF99000.1 - 0.0078 15.7 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.16 OAF99000.1 - 0.011 15.5 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 OAF99000.1 - 0.089 12.6 0.2 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAF99000.1 - 0.098 12.1 0.2 4 6.8 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Fcf1 PF04900.12 OAF99001.1 - 1.4e-33 115.3 0.3 2.1e-33 114.7 0.3 1.3 1 0 0 1 1 1 1 Fcf1 Presenilin PF01080.17 OAF99001.1 - 5.7 5.6 4.3 7.3 5.2 4.3 1.2 1 0 0 1 1 1 0 Presenilin DUF726 PF05277.12 OAF99002.1 - 1.2e-122 409.2 1.8 1.6e-122 408.7 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SpoOE-like PF09388.10 OAF99002.1 - 0.028 14.3 0.7 0.071 13.0 0.7 1.7 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein HSDR_N PF04313.14 OAF99002.1 - 0.043 13.8 0.9 0.11 12.4 0.9 1.6 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF1761 PF08570.10 OAF99002.1 - 0.08 13.2 0.5 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) adh_short PF00106.25 OAF99003.1 - 2.6e-19 69.4 0.0 7.4e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99003.1 - 6.7e-11 42.2 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAF99003.1 - 9.9e-07 28.8 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAF99003.1 - 0.22 10.9 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cu-oxidase_2 PF07731.14 OAF99004.1 - 3.3e-24 85.2 0.8 4.3e-22 78.3 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAF99004.1 - 3.9e-18 65.6 1.5 6e-18 65.0 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAF99004.1 - 3.9e-05 23.8 0.0 0.00017 21.7 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Peroxidase_2 PF01328.17 OAF99005.1 - 1.1e-45 156.4 0.0 1.6e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF2515 PF10720.9 OAF99005.1 - 0.039 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) CFEM PF05730.11 OAF99007.1 - 3.2e-11 43.2 11.7 6e-11 42.3 11.7 1.5 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.19 OAF99008.1 - 1.3e-25 90.4 0.0 4.4e-17 62.4 0.0 3.5 4 0 0 4 4 4 3 GMC oxidoreductase GMC_oxred_C PF05199.13 OAF99008.1 - 5.8e-25 88.5 0.0 1.1e-24 87.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAF99008.1 - 7.3e-05 22.1 0.1 0.00047 19.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAF99008.1 - 0.0025 17.4 0.2 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAF99008.1 - 0.0039 16.3 0.1 0.029 13.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAF99008.1 - 0.0046 17.2 0.3 0.016 15.4 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 OAF99008.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 OAF99008.1 - 0.19 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAF99008.1 - 0.21 10.8 0.1 24 4.1 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 OAF99009.1 - 1.3e-21 76.5 4.9 2e-21 75.9 4.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAF99009.1 - 2.8e-18 66.1 0.0 4.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAF99009.1 - 2.2e-05 25.5 0.0 3.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAF99009.1 - 0.00046 19.6 0.1 0.00075 18.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAF99009.1 - 0.0082 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ComGG PF14173.6 OAF99009.1 - 0.078 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 ComG operon protein 7 CAP59_mtransfer PF11735.8 OAF99010.1 - 5e-65 219.5 0.0 6.6e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Dynamitin PF04912.14 OAF99011.1 - 3e-84 283.6 6.1 3.5e-84 283.4 6.1 1.0 1 0 0 1 1 1 1 Dynamitin Prefoldin_2 PF01920.20 OAF99011.1 - 0.039 13.9 1.2 0.039 13.9 1.2 3.5 4 0 0 4 4 4 0 Prefoldin subunit DUF16 PF01519.16 OAF99011.1 - 0.082 13.4 9.1 0.43 11.1 0.6 3.8 4 0 0 4 4 4 0 Protein of unknown function DUF16 Golgin_A5 PF09787.9 OAF99011.1 - 0.093 12.2 13.9 0.72 9.3 4.7 3.0 2 1 1 3 3 3 0 Golgin subfamily A member 5 Laminin_II PF06009.12 OAF99011.1 - 0.12 12.4 8.8 0.33 11.0 1.0 3.5 4 0 0 4 4 4 0 Laminin Domain II DUF2730 PF10805.8 OAF99011.1 - 0.14 12.3 1.4 22 5.2 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) ORF6C PF10552.9 OAF99011.1 - 0.2 11.7 4.1 7.2 6.7 0.6 3.1 3 0 0 3 3 3 0 ORF6C domain DUF812 PF05667.11 OAF99011.1 - 0.31 9.9 9.5 0.021 13.7 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) OmpH PF03938.14 OAF99011.1 - 0.65 10.3 13.2 0.96 9.8 0.8 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Nup54 PF13874.6 OAF99011.1 - 1 9.4 10.1 0.19 11.8 0.9 3.0 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 IFP_35_N PF07334.13 OAF99011.1 - 1.2 9.2 16.8 12 6.1 2.9 4.5 4 1 0 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AAA_13 PF13166.6 OAF99011.1 - 1.7 7.2 9.1 1.3 7.5 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF1319 PF07028.11 OAF99011.1 - 1.9 8.7 4.7 61 3.9 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) TMPIT PF07851.13 OAF99011.1 - 2.8 7.1 4.4 2.2 7.4 0.6 2.2 2 0 0 2 2 2 0 TMPIT-like protein IFT46_B_C PF12317.8 OAF99011.1 - 3.2 7.4 8.0 0.73 9.5 3.0 2.3 2 1 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal DUF4200 PF13863.6 OAF99011.1 - 3.4 8.1 13.4 0.18 12.2 1.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 OAF99011.1 - 3.7 6.8 10.4 2.3 7.5 2.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 OAF99011.1 - 3.8 8.1 14.4 9.5 6.9 4.6 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.7 OAF99011.1 - 4 7.6 15.8 0.048 13.8 1.5 3.1 3 0 0 3 3 3 0 Tropomyosin like YlqD PF11068.8 OAF99011.1 - 4.3 7.7 15.7 1.8 9.0 0.6 3.2 4 0 0 4 4 3 0 YlqD protein CdvA PF18822.1 OAF99011.1 - 4.9 7.0 10.9 2.3 8.1 0.2 3.1 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Spc7 PF08317.11 OAF99011.1 - 5.5 5.8 13.9 1.9 7.3 7.0 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein CPSase_L_D2 PF02786.17 OAF99012.1 - 9.2e-107 355.3 0.0 5e-81 271.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 OAF99012.1 - 3e-40 137.4 0.1 7e-40 136.2 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 OAF99012.1 - 3.6e-19 69.1 0.5 6.5e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAF99012.1 - 6.6e-19 68.1 0.0 7.2e-10 38.7 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAF99012.1 - 2.3e-11 43.6 0.0 3.1e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 OAF99012.1 - 7.6e-08 32.2 0.0 5.9e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 OAF99012.1 - 3.2e-06 27.1 0.1 0.0056 16.5 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 OAF99012.1 - 4.4e-05 23.6 0.2 0.041 13.9 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 OAF99012.1 - 6.4e-05 22.5 0.8 0.043 13.3 0.1 3.3 3 1 1 4 4 4 2 ATP-grasp domain MGS PF02142.22 OAF99012.1 - 0.0013 18.8 0.0 0.012 15.8 0.0 2.5 2 1 1 3 3 3 1 MGS-like domain RuvA_C PF07499.13 OAF99012.1 - 0.027 14.9 0.1 14 6.2 0.0 3.0 2 0 0 2 2 2 0 RuvA, C-terminal domain GSH-S_ATP PF02955.16 OAF99012.1 - 0.12 11.8 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain SNase PF00565.17 OAF99013.1 - 4e-23 82.0 0.6 4e-23 82.0 0.6 1.4 2 0 0 2 2 2 1 Staphylococcal nuclease homologue GP46 PF07409.12 OAF99013.1 - 0.045 13.5 0.1 0.093 12.5 0.1 1.5 1 0 0 1 1 1 0 Phage protein GP46 Amino_oxidase PF01593.24 OAF99014.1 - 1.4e-84 285.0 0.1 1.1e-83 282.0 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 OAF99014.1 - 6.5e-15 55.3 0.0 1.6e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 OAF99014.1 - 2e-08 34.3 0.1 5.9e-08 32.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 OAF99014.1 - 0.00045 20.6 1.2 0.0029 18.0 0.1 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.24 OAF99014.1 - 0.0018 17.9 0.0 0.0045 16.6 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAF99014.1 - 0.0073 15.6 0.1 0.041 13.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAF99014.1 - 0.061 13.3 0.1 0.96 9.4 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding BSMAP PF12280.8 OAF99014.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Brain specific membrane anchored protein UCH PF00443.29 OAF99015.1 - 1.5e-55 188.5 0.0 3.1e-55 187.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAF99015.1 - 1.6e-26 93.6 0.3 2.1e-20 73.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OAF99015.1 - 0.37 10.2 10.6 0.086 12.3 1.5 3.1 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase HrpA_pilin PF09589.10 OAF99015.1 - 3.2 8.5 6.6 1.2 9.8 2.0 2.3 2 0 0 2 2 2 0 HrpA pilus formation protein Pol_alpha_B_N PF08418.10 OAF99017.1 - 0.0018 18.3 2.0 0.0021 18.1 2.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Med19 PF10278.9 OAF99017.1 - 0.0079 16.1 14.3 0.009 16.0 14.3 1.1 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.9 OAF99017.1 - 0.011 15.3 17.8 0.013 15.1 17.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SRP9-21 PF05486.12 OAF99017.1 - 0.018 15.4 5.1 0.022 15.1 5.1 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) DUF4770 PF15994.5 OAF99017.1 - 0.025 14.8 7.3 0.03 14.6 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Protocadherin PF08374.11 OAF99017.1 - 0.051 13.5 7.0 0.058 13.4 7.0 1.1 1 0 0 1 1 1 0 Protocadherin Mlh1_C PF16413.5 OAF99017.1 - 0.054 12.9 0.9 0.058 12.8 0.9 1.0 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus Peptidase_S49_N PF08496.10 OAF99017.1 - 0.089 12.9 9.5 0.1 12.7 9.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pox_Ag35 PF03286.14 OAF99017.1 - 0.23 11.2 9.8 0.29 10.9 9.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3464 PF11947.8 OAF99017.1 - 0.24 11.1 6.0 0.29 10.9 6.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 OAD_gamma PF04277.13 OAF99017.1 - 0.31 11.7 5.6 0.42 11.3 5.6 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain BCIP PF13862.6 OAF99017.1 - 0.32 10.7 7.5 0.4 10.4 7.5 1.1 1 0 0 1 1 1 0 p21-C-terminal region-binding protein DUF4604 PF15377.6 OAF99017.1 - 0.42 11.0 15.0 0.47 10.9 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Connexin PF00029.19 OAF99017.1 - 0.66 9.7 3.2 0.73 9.5 3.2 1.1 1 0 0 1 1 1 0 Connexin Herpes_DNAp_acc PF04929.12 OAF99017.1 - 0.8 8.6 8.1 1.9 7.4 7.5 1.7 2 0 0 2 2 2 0 Herpes DNA replication accessory factor TSGP1 PF07771.11 OAF99017.1 - 0.8 9.9 13.7 1.1 9.4 13.7 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 AP3D1 PF06375.11 OAF99017.1 - 1.1 9.5 18.7 1.4 9.1 18.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Jak1_Phl PF17887.1 OAF99017.1 - 1.2 9.1 7.5 1.4 8.8 7.5 1.1 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Red1 PF07964.11 OAF99017.1 - 1.9 6.6 15.2 2.5 6.3 15.2 1.0 1 0 0 1 1 1 0 Rec10 / Red1 RNA_polI_A34 PF08208.11 OAF99017.1 - 3.1 7.8 20.0 3.8 7.5 20.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Yos1 PF08571.10 OAF99018.1 - 9e-33 112.4 0.2 1e-32 112.2 0.2 1.0 1 0 0 1 1 1 1 Yos1-like HATPase_c PF02518.26 OAF99019.1 - 7.3e-30 103.8 0.2 1.6e-29 102.7 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAF99019.1 - 8e-23 80.7 0.3 2e-22 79.5 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAF99019.1 - 5.7e-20 71.1 0.0 2e-19 69.4 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAF99019.1 - 1.6e-18 66.7 3.6 3e-18 65.9 2.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAF99019.1 - 7.8e-18 64.7 0.5 2.9e-10 40.4 0.1 4.5 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 OAF99019.1 - 1.3e-15 57.5 0.0 1.2e-08 35.1 0.0 4.6 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 OAF99019.1 - 4e-15 55.8 0.1 3.4e-08 33.5 0.0 4.2 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 OAF99019.1 - 0.00027 20.9 0.0 2.1 8.5 0.0 3.5 3 0 0 3 3 3 2 PAS domain HATPase_c_3 PF13589.6 OAF99019.1 - 0.026 14.4 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1835 PF08874.10 OAF99019.1 - 0.035 14.3 0.5 0.83 9.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) zf-C2H2 PF00096.26 OAF99020.1 - 3.2e-10 39.9 11.4 1.5e-05 25.2 4.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAF99020.1 - 1.5e-09 37.8 13.0 5.3e-05 23.5 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAF99020.1 - 4.2e-07 30.2 10.6 0.00064 20.3 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAF99020.1 - 7e-06 26.3 1.2 1.9e-05 24.9 1.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAF99020.1 - 0.00014 21.7 2.1 0.00014 21.7 2.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAF99020.1 - 0.00088 19.5 5.0 0.0011 19.2 2.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAF99020.1 - 0.084 13.2 1.9 0.13 12.6 1.2 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 OAF99020.1 - 0.16 11.9 5.0 4 7.4 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 OAF99020.1 - 0.44 10.4 9.3 1.4 8.7 1.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 OAF99020.1 - 2.5 8.2 5.4 0.96 9.5 0.9 2.3 2 0 0 2 2 2 0 BED zinc finger NuA4 PF09340.10 OAF99021.1 - 4.5e-27 93.7 0.4 4.5e-27 93.7 0.4 1.5 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 TFIIS_M PF07500.14 OAF99022.1 - 3.5e-29 101.5 3.8 3.6e-29 101.5 2.4 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OAF99022.1 - 1.1e-17 63.6 8.7 1.7e-17 63.0 8.7 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OAF99022.1 - 5.1e-13 48.8 1.4 1.1e-12 47.8 0.2 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zf-CHY PF05495.12 OAF99022.1 - 0.016 15.6 1.9 0.036 14.6 1.9 1.5 1 1 0 1 1 1 0 CHY zinc finger WD40 PF00400.32 OAF99023.1 - 8.5e-52 172.0 25.8 7.8e-06 26.5 0.2 12.2 12 1 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.12 OAF99023.1 - 5e-20 71.8 0.1 1e-19 70.8 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAF99023.1 - 9.3e-20 70.7 7.4 0.0059 16.9 0.0 9.9 6 4 4 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAF99023.1 - 2.2e-08 33.2 6.3 0.13 10.9 0.1 6.2 4 2 1 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAF99023.1 - 2.9e-08 33.0 5.6 0.28 10.1 0.0 7.1 2 2 5 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAF99023.1 - 0.0013 18.7 0.1 1.9 8.3 0.0 4.7 5 1 1 6 6 6 1 Eukaryotic translation initiation factor eIF2A Utp21 PF04192.12 OAF99023.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain VID27 PF08553.10 OAF99023.1 - 0.16 11.0 0.0 0.42 9.6 0.0 1.6 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain WD40_like PF17005.5 OAF99023.1 - 0.17 11.2 0.0 68 2.6 0.0 3.8 4 0 0 4 4 4 0 WD40-like domain RRP36 PF06102.12 OAF99023.1 - 1.1 9.2 6.9 1.6 8.7 2.2 2.3 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 P34-Arc PF04045.14 OAF99024.1 - 7.4e-109 363.1 0.8 8.9e-109 362.8 0.8 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 OAF99024.1 - 0.0037 16.9 0.1 0.0077 15.9 0.1 1.5 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.21 OAF99024.1 - 0.067 13.6 0.4 0.93 9.8 0.3 2.4 1 1 1 2 2 2 0 Radical SAM superfamily Dus PF01207.17 OAF99025.1 - 6.8e-47 160.1 0.0 3e-46 157.9 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF2956 PF11169.8 OAF99025.1 - 0.2 11.8 3.5 0.46 10.7 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Ribosomal_60s PF00428.19 OAF99025.1 - 0.3 11.7 4.0 0.65 10.6 4.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SpoVR PF04293.13 OAF99025.1 - 0.43 9.2 1.1 0.62 8.7 1.1 1.1 1 0 0 1 1 1 0 SpoVR like protein Pyr_redox_2 PF07992.14 OAF99028.1 - 1.4e-11 44.2 0.0 6e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAF99028.1 - 1.1e-09 37.9 0.0 2.8e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAF99028.1 - 1.1e-08 35.2 0.0 5.8e-08 32.8 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAF99028.1 - 4.8e-08 31.9 0.2 4e-07 28.8 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAF99028.1 - 4.1e-07 29.5 0.2 4.6e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAF99028.1 - 0.0059 15.9 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAF99028.1 - 0.011 15.7 0.3 1.9 8.5 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Mqo PF06039.15 OAF99028.1 - 0.063 11.8 0.0 3.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) T5orf172 PF10544.9 OAF99029.1 - 2.2e-15 57.0 0.1 8.1e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 OAF99029.1 - 1.2e-10 41.9 0.5 2.9e-10 40.7 0.1 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 Tox-URI2 PF15653.6 OAF99029.1 - 0.14 12.4 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 URI fold toxin 2 Glutaredoxin PF00462.24 OAF99031.1 - 1.5e-20 73.1 0.0 1.4e-18 66.9 0.0 2.7 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 OAF99031.1 - 4.5e-16 58.7 0.0 9.3e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAF99031.1 - 0.0063 16.8 0.0 0.18 12.1 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like HyaE PF07449.11 OAF99031.1 - 0.0064 16.4 0.1 0.05 13.6 0.0 2.4 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE APC_basic PF05956.11 OAF99031.1 - 0.019 14.5 0.2 0.024 14.1 0.2 1.1 1 0 0 1 1 1 0 APC basic domain TraF PF13728.6 OAF99031.1 - 0.078 12.8 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 OAF99031.1 - 0.094 13.2 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Brix PF04427.18 OAF99032.1 - 7.3e-36 124.1 0.1 9.8e-36 123.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain SapB_2 PF03489.17 OAF99032.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Saposin-like type B, region 2 MMS19_C PF12460.8 OAF99033.1 - 1.3e-106 357.3 5.8 3.8e-105 352.5 1.5 3.6 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 OAF99033.1 - 9.4e-96 320.4 0.1 4.8e-92 308.2 0.0 3.5 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 OAF99033.1 - 0.025 15.1 11.7 0.16 12.5 0.7 6.0 6 1 0 6 6 6 0 HEAT-like repeat Telomere_reg-2 PF10193.9 OAF99033.1 - 0.035 14.6 0.3 3 8.3 0.0 3.8 4 0 0 4 4 4 0 Telomere length regulation protein HEAT PF02985.22 OAF99033.1 - 0.04 14.2 5.9 21 5.7 0.5 6.0 6 0 0 6 6 6 0 HEAT repeat RICTOR_N PF14664.6 OAF99033.1 - 0.24 10.4 1.4 11 4.8 0.0 2.9 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_2 PF13646.6 OAF99033.1 - 0.38 11.2 14.4 0.15 12.4 1.2 5.8 7 0 0 7 7 7 0 HEAT repeats THF_DHG_CYH PF00763.23 OAF99034.1 - 9.4e-24 83.9 0.1 1.5e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OAF99034.1 - 1.6e-13 50.3 0.2 1.4e-09 37.5 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain A_deaminase PF00962.22 OAF99037.1 - 1.4e-120 402.6 0.0 2e-120 402.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase PMT PF02366.18 OAF99038.1 - 2.6e-85 285.9 15.6 2.6e-85 285.9 15.6 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UAA PF08449.11 OAF99038.1 - 5.3e-80 268.8 14.2 5.3e-80 268.8 14.2 1.9 2 0 0 2 2 2 1 UAA transporter family PMT_4TMC PF16192.5 OAF99038.1 - 4.8e-69 231.9 4.6 4.8e-69 231.9 4.6 4.5 3 1 1 4 4 4 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAF99038.1 - 4.1e-19 69.1 0.8 7.9e-19 68.2 0.8 1.5 1 0 0 1 1 1 1 MIR domain WD40 PF00400.32 OAF99039.1 - 9.2e-13 48.5 3.3 0.12 13.3 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAF99039.1 - 0.012 15.9 0.1 3.5 8.0 0.0 3.6 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L3 PF00297.22 OAF99040.1 - 6.2e-183 607.9 8.6 7e-183 607.7 8.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 FAD_binding_2 PF00890.24 OAF99041.1 - 3.6e-127 424.9 2.3 4.6e-127 424.6 2.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAF99041.1 - 1.6e-44 151.0 0.4 2.4e-44 150.4 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 OAF99041.1 - 2.7e-06 26.9 0.1 0.0018 17.6 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAF99041.1 - 1.1e-05 24.7 1.8 0.012 14.7 1.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAF99041.1 - 4.5e-05 22.8 0.1 0.032 13.5 0.1 2.6 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.19 OAF99041.1 - 0.0031 16.8 0.1 0.0058 15.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAF99041.1 - 0.044 12.5 0.1 0.19 10.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 OAF99041.1 - 0.05 13.2 2.4 0.31 10.6 2.4 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 OAF99042.1 - 5.8e-55 186.8 0.0 7.4e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAF99042.1 - 6.3e-35 120.8 0.1 1.5e-34 119.6 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 OAF99042.1 - 0.00019 21.2 1.4 0.0021 17.7 1.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAF99042.1 - 0.00056 19.1 0.2 0.0013 17.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAF99042.1 - 0.00066 19.0 0.2 0.1 11.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAF99042.1 - 0.0015 18.7 0.5 0.0056 16.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAF99042.1 - 0.006 15.7 0.0 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAF99042.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 OAF99042.1 - 0.044 14.0 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Glyco_transf_28 PF03033.20 OAF99043.1 - 2.1e-20 73.2 0.0 4.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAF99043.1 - 1.1e-05 24.5 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 OAF99043.1 - 0.0068 16.2 2.6 0.015 15.1 1.2 2.1 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal GST_N PF02798.20 OAF99044.1 - 6.8e-11 42.4 0.0 1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAF99044.1 - 1.1e-05 25.7 0.0 2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAF99044.1 - 0.0087 16.3 0.0 0.018 15.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Ank_2 PF12796.7 OAF99045.1 - 1.7e-42 143.9 0.0 1.4e-13 51.2 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAF99045.1 - 1.1e-32 112.0 0.0 2.6e-07 31.0 0.0 5.4 2 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAF99045.1 - 3e-31 104.0 0.0 0.00066 19.9 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 OAF99045.1 - 1.4e-28 98.1 6.1 0.00028 21.2 0.1 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OAF99045.1 - 1e-20 73.5 5.9 0.00057 20.1 0.1 7.1 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Glyoxalase PF00903.25 OAF99046.1 - 7.3e-10 39.1 0.0 1.3e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAF99046.1 - 7.6e-05 23.0 0.0 9.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAF99046.1 - 0.00026 21.2 0.0 0.0011 19.2 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 OAF99046.1 - 0.00065 20.5 0.0 0.0022 18.8 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OAF99046.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.5 2 0 0 2 2 2 0 Glyoxalase-like domain CBFB_NFYA PF02045.15 OAF99047.1 - 6.3e-28 97.2 3.3 6.3e-28 97.2 3.3 1.9 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 OAF99047.1 - 0.0095 16.0 26.6 0.012 15.6 26.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4604 PF15377.6 OAF99047.1 - 1 9.7 16.5 2 8.8 12.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Hus1 PF04005.12 OAF99047.1 - 2.4 7.2 4.1 0.29 10.2 0.1 1.4 2 0 0 2 2 2 0 Hus1-like protein PGA2 PF07543.12 OAF99047.1 - 4.4 7.3 7.9 8.9 6.3 7.9 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 TFIIE-A_C PF11521.8 OAF99047.1 - 4.8 7.5 9.4 22 5.4 6.1 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF3659 PF12396.8 OAF99050.1 - 0 1017.8 192.5 6.2e-25 86.9 2.1 15.8 15 0 0 15 15 15 15 Protein of unknown function (DUF3659) DUF2167 PF09935.9 OAF99050.1 - 0.084 12.0 5.9 0.032 13.4 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) RPW8 PF05659.11 OAF99050.1 - 0.56 9.9 1.9 3.2 7.4 0.3 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Big_8 PF17961.1 OAF99050.1 - 0.69 10.1 13.5 20 5.4 0.0 7.8 9 1 0 9 9 9 0 Bacterial Ig domain Phage_fiber_C PF06820.12 OAF99050.1 - 0.74 10.2 6.5 39 4.7 0.0 6.3 6 1 1 7 7 7 0 Putative prophage tail fibre C-terminus CorA PF01544.18 OAF99050.1 - 0.96 8.7 3.2 2.6 7.3 3.2 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IQ PF00612.27 OAF99052.1 - 0.00021 20.8 1.2 0.00032 20.2 1.2 1.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4246 PF14033.6 OAF99053.1 - 1.8e-176 587.8 0.0 2e-176 587.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 OAF99053.1 - 0.057 13.8 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Oxidored_FMN PF00724.20 OAF99054.1 - 1.2e-41 143.2 0.0 1.6e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 OAF99055.1 - 3.5e-32 111.7 18.3 5.5e-16 58.4 10.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF99055.1 - 1.1e-10 41.1 12.2 2.9e-06 26.4 7.0 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 OAF99055.1 - 7.2e-09 34.7 16.1 1.6e-06 27.0 9.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAF99055.1 - 0.012 14.4 10.9 0.098 11.5 4.2 2.3 1 1 0 2 2 2 0 MFS_1 like family OATP PF03137.20 OAF99055.1 - 0.025 12.9 6.8 2 6.6 0.1 3.1 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 OAF99055.1 - 0.5 8.7 12.1 0.27 9.6 3.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector LacY_symp PF01306.19 OAF99055.1 - 2.9 6.6 12.6 1.3 7.7 4.6 2.6 2 2 0 2 2 2 0 LacY proton/sugar symporter VRR_NUC PF08774.11 OAF99056.1 - 3.8e-20 72.0 0.0 9.3e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Glyco_hydro_25 PF01183.20 OAF99058.1 - 2.1e-31 109.5 0.0 2.4e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Glyco_hydro_cc PF11790.8 OAF99060.1 - 1.7e-32 112.9 0.9 2e-32 112.7 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FAD_binding_3 PF01494.19 OAF99061.1 - 2.8e-25 89.3 0.0 5e-24 85.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAF99061.1 - 0.00013 21.0 0.2 0.0032 16.4 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 OAF99061.1 - 0.00083 19.5 0.5 0.002 18.3 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAF99061.1 - 0.018 14.1 0.5 0.03 13.4 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAF99061.1 - 0.057 13.0 0.7 0.27 10.8 0.7 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAF99061.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aspzincin_M35 PF14521.6 OAF99062.1 - 9.5e-09 35.9 0.6 1.7e-07 31.9 0.6 2.3 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 OAF99062.1 - 2.1e-05 24.2 0.1 0.11 12.0 0.0 2.1 2 0 0 2 2 2 2 Putative peptidase family fn3 PF00041.21 OAF99063.1 - 0.0027 18.0 0.0 0.027 14.8 0.0 2.3 1 1 0 1 1 1 1 Fibronectin type III domain p450 PF00067.22 OAF99064.1 - 2.4e-45 155.2 0.0 3.3e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_31 PF01055.26 OAF99065.1 - 6.2e-62 210.2 1.5 8.6e-62 209.7 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Zn_clus PF00172.18 OAF99066.1 - 1.4e-07 31.5 11.9 2.6e-07 30.7 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAF99066.1 - 0.00022 20.3 0.4 0.00043 19.4 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2401 PF10287.9 OAF99067.1 - 8.9e-72 241.4 0.0 1.1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 OAF99067.1 - 0.0033 17.8 0.0 0.0078 16.6 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Ribosomal_S13_N PF08069.12 OAF99068.1 - 4.7e-29 100.2 0.1 7.6e-29 99.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OAF99068.1 - 3.1e-14 52.9 0.1 4.2e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 OAF99068.1 - 0.011 15.6 0.1 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 OAF99069.1 - 1.8e-12 46.8 0.2 2.8e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 Dpy-30 motif DUF3306 PF11748.8 OAF99069.1 - 7.1 7.5 9.0 53 4.7 9.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Mucin PF01456.17 OAF99069.1 - 9.4 6.2 13.2 13 5.8 13.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MYCBPAP PF14646.6 OAF99070.1 - 0.039 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family ANAPC_CDC26 PF10471.9 OAF99072.1 - 4.5e-15 56.2 7.9 5.5e-15 56.0 7.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Glyco_hydro_16 PF00722.21 OAF99073.1 - 3.4e-07 29.9 0.0 3.1e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Metallothio_Pro PF02069.16 OAF99073.1 - 0.15 12.4 0.4 0.28 11.4 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein DUF2235 PF09994.9 OAF99074.1 - 2e-79 267.0 0.1 2.9e-79 266.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ANAPC2 PF08672.11 OAF99074.1 - 0.12 12.9 0.0 5 7.7 0.0 2.4 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 7tm_2 PF00002.24 OAF99076.1 - 0.0012 18.2 10.9 0.0012 18.2 10.9 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) DC_STAMP PF07782.13 OAF99076.1 - 1.4 8.7 4.8 6.6 6.5 4.8 2.1 1 1 0 1 1 1 0 DC-STAMP-like protein 2-Hacid_dh_C PF02826.19 OAF99078.1 - 5.3e-46 156.2 0.1 8e-29 100.3 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAF99078.1 - 0.00027 20.6 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 OAF99078.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 OAF99078.1 - 0.013 16.0 0.0 0.028 14.9 0.0 1.6 1 1 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 OAF99078.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAF99078.1 - 0.16 12.1 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF846 PF05832.12 OAF99079.1 - 1.4e-51 174.2 6.9 1.7e-51 173.9 6.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.6 OAF99079.1 - 0.41 10.0 2.4 0.38 10.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) HpcH_HpaI PF03328.14 OAF99080.1 - 3.4e-45 153.9 0.0 7.2e-45 152.8 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OAF99080.1 - 5e-13 48.9 0.1 1.5e-05 24.4 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Methyltransf_28 PF02636.17 OAF99081.1 - 2.1e-38 132.4 0.0 2.8e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PALP PF00291.25 OAF99082.1 - 1.4e-64 218.3 0.1 1.7e-64 218.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S9 PF00326.21 OAF99084.1 - 2e-55 187.6 0.3 3.9e-55 186.6 0.2 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 OAF99084.1 - 0.018 13.8 0.3 0.4 9.3 0.3 2.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) TPR_12 PF13424.6 OAF99085.1 - 5.7e-65 215.6 27.6 1.4e-16 60.5 0.6 6.0 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 OAF99085.1 - 1.4e-55 183.7 6.2 1.1e-11 44.2 0.2 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 OAF99085.1 - 2e-13 49.5 17.9 0.053 13.4 0.1 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAF99085.1 - 2.3e-13 49.1 18.2 0.047 13.8 0.1 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAF99085.1 - 1e-12 47.1 11.8 0.0069 16.3 0.2 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAF99085.1 - 3.2e-12 46.2 7.4 0.028 15.2 0.0 7.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAF99085.1 - 1.5e-11 44.7 10.2 9e-05 23.0 0.0 6.6 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAF99085.1 - 1.2e-10 40.7 14.2 0.002 18.2 0.0 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat HET PF06985.11 OAF99085.1 - 4.4e-08 33.6 12.2 2.8e-07 31.0 0.6 3.0 2 1 1 3 3 2 2 Heterokaryon incompatibility protein (HET) TPR_MalT PF17874.1 OAF99085.1 - 5.1e-08 32.7 8.2 5.7e-05 22.6 2.0 2.7 1 1 1 2 2 2 2 MalT-like TPR region NB-ARC PF00931.22 OAF99085.1 - 5.1e-06 25.9 0.0 3.7e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 OAF99085.1 - 1.1e-05 25.9 5.6 0.078 13.5 0.3 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAF99085.1 - 1.2e-05 25.8 0.7 4.4e-05 23.9 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 OAF99085.1 - 4.7e-05 23.4 0.0 8.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAF99085.1 - 0.0035 17.6 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_17 PF13431.6 OAF99085.1 - 0.094 13.1 3.4 53 4.5 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat PhoH PF02562.16 OAF99085.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein TPR_6 PF13174.6 OAF99085.1 - 2.4 9.0 7.0 58 4.6 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SHD1 PF03983.12 OAF99086.1 - 4.5e-34 116.1 0.0 8.1e-34 115.3 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 OAF99086.1 - 7e-34 115.2 9.7 8.1e-13 47.8 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 OAF99086.1 - 5e-31 106.3 7.2 1.5e-10 40.8 0.1 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 OAF99086.1 - 2.2e-22 78.5 0.0 2.6e-08 33.4 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.11 OAF99086.1 - 1.5e-07 31.7 58.9 1.5e-06 28.5 32.6 7.5 2 2 4 6 6 6 3 Domain of unknown function (DUF1720) SH3_10 PF17902.1 OAF99086.1 - 0.0024 17.9 0.0 0.59 10.2 0.0 3.1 3 0 0 3 3 3 1 SH3 domain SAM_4 PF18017.1 OAF99086.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 OAF99086.1 - 0.018 15.3 4.6 1.4 9.3 0.6 3.1 3 0 0 3 3 3 0 Bacterial SH3 domain MFS_1 PF07690.16 OAF99087.1 - 2.1e-31 109.1 25.3 2.1e-31 109.1 25.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2157 PF09925.9 OAF99087.1 - 3.7 7.3 12.1 3.4e+02 1.0 12.1 3.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) adh_short PF00106.25 OAF99088.1 - 8.1e-26 90.7 0.0 4.3e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99088.1 - 1.1e-15 57.9 0.0 1.5e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAF99088.1 - 4.8e-06 26.6 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF812 PF05667.11 OAF99092.1 - 0.041 12.8 1.8 0.056 12.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 OAF99092.1 - 0.092 11.4 2.9 0.14 10.8 2.9 1.2 1 0 0 1 1 1 0 AAA domain FliE PF02049.18 OAF99092.1 - 1.3 9.2 3.6 1.1 9.4 0.1 2.6 2 1 2 4 4 4 0 Flagellar hook-basal body complex protein FliE Spc7 PF08317.11 OAF99092.1 - 1.3 7.8 7.3 2.1 7.1 7.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein SelP_N PF04592.14 OAF99092.1 - 4.7 6.5 9.2 8.9 5.6 9.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region THOC7 PF05615.13 OAF99092.1 - 5.1 7.4 12.1 13 6.1 12.1 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 FUSC PF04632.12 OAF99092.1 - 7.3 5.0 8.6 2.8 6.4 5.3 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family ABC_tran_CTD PF16326.5 OAF99092.1 - 8.3 6.7 8.7 0.74 10.1 1.1 2.7 3 1 0 3 3 3 0 ABC transporter C-terminal domain Cgr1 PF03879.14 OAF99093.1 - 2.7e-30 104.9 34.1 3.1e-30 104.7 34.1 1.0 1 0 0 1 1 1 1 Cgr1 family FlaF PF07309.11 OAF99093.1 - 2.1 8.4 10.0 0.27 11.2 5.1 1.9 1 1 1 2 2 2 0 Flagellar protein FlaF TMPIT PF07851.13 OAF99093.1 - 4.2 6.5 6.7 4.9 6.3 6.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mito_carr PF00153.27 OAF99094.1 - 1.2e-64 214.3 1.1 9.8e-22 76.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1925 PF09094.11 OAF99094.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) Tim17 PF02466.19 OAF99094.1 - 0.25 11.7 2.2 1.8 8.9 2.2 2.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Tim17 PF02466.19 OAF99095.1 - 8.2e-14 51.9 0.3 1.5e-13 51.1 0.3 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CFEM PF05730.11 OAF99096.1 - 4.5e-11 42.7 8.3 7.5e-11 42.0 8.3 1.4 1 0 0 1 1 1 1 CFEM domain DUF5305 PF17231.2 OAF99096.1 - 0.017 14.5 0.2 0.044 13.2 0.3 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5305) SWI-SNF_Ssr4 PF08549.10 OAF99096.1 - 2 7.0 4.4 2.9 6.4 4.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Glyco_transf_34 PF05637.12 OAF99098.1 - 6.7e-66 222.4 0.7 9.1e-66 222.0 0.7 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Virul_fac_BrkB PF03631.15 OAF99098.1 - 0.081 12.5 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF349 PF03993.12 OAF99098.1 - 2.7 8.3 9.6 0.56 10.5 5.5 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) OppC_N PF12911.7 OAF99099.1 - 0.035 14.1 0.4 0.096 12.7 0.0 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3671 PF12420.8 OAF99099.1 - 0.061 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function SNARE PF05739.19 OAF99099.1 - 0.15 12.1 5.0 0.36 10.8 5.0 1.6 1 0 0 1 1 1 0 SNARE domain Sugar_tr PF00083.24 OAF99101.1 - 1.8e-26 93.1 19.3 7.8e-24 84.3 19.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99101.1 - 4.8e-08 32.3 33.2 1.2e-05 24.5 11.0 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Baculo_p74 PF04583.12 OAF99101.1 - 4.8 6.6 5.4 2 7.8 2.2 1.8 2 0 0 2 2 2 0 Baculoviridae p74 conserved region TspO_MBR PF03073.15 OAF99102.1 - 1.1e-45 155.0 8.5 1.6e-45 154.5 8.5 1.1 1 0 0 1 1 1 1 TspO/MBR family PIR PF00399.19 OAF99104.1 - 3.5e-05 23.2 6.7 0.0001 21.7 6.7 1.9 1 0 0 1 1 1 1 Yeast PIR protein repeat FdhD-NarQ PF02634.15 OAF99107.1 - 0.053 13.2 0.1 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 FdhD/NarQ family Bromo_TP PF07524.13 OAF99108.1 - 3.5e-09 36.5 0.0 1.8e-08 34.2 0.0 2.2 3 0 0 3 3 3 1 Bromodomain associated TFIID-31kDa PF02291.15 OAF99108.1 - 0.0011 19.1 0.1 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit TAFII55_N PF04658.13 OAF99109.1 - 6e-46 156.1 0.0 1e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region Fib_succ_major PF09603.10 OAF99110.1 - 0.0019 18.8 1.9 0.0028 18.3 1.9 1.3 1 0 0 1 1 1 1 Fibrobacter succinogenes major domain (Fib_succ_major) Acetyltransf_3 PF13302.7 OAF99110.1 - 0.021 15.5 0.7 0.026 15.2 0.7 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec63 PF02889.16 OAF99111.1 - 2.3e-164 544.7 0.1 7.9e-91 303.8 0.0 2.8 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 OAF99111.1 - 7.7e-48 162.6 0.0 7.7e-27 94.2 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OAF99111.1 - 1.8e-32 111.8 1.6 1.8e-32 111.8 1.6 2.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 OAF99111.1 - 1.4e-23 83.7 0.0 1.4e-12 48.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAF99111.1 - 8.2e-10 39.0 0.0 2.8e-08 34.1 0.0 3.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAF99111.1 - 8.4e-05 22.4 0.0 0.024 14.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 OAF99111.1 - 0.00017 21.8 0.1 0.25 11.6 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAF99111.1 - 0.011 16.1 0.0 3.9 7.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAF99111.1 - 0.018 14.5 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 OAF99111.1 - 0.024 14.2 0.4 3.9 6.9 0.0 3.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain DUF905 PF06006.12 OAF99114.1 - 0.0049 16.8 0.2 0.0088 16.0 0.2 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF905) Met_10 PF02475.16 OAF99115.1 - 3.1e-67 226.2 0.0 4e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 OAF99115.1 - 0.0015 17.8 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Kinesin PF00225.23 OAF99116.1 - 7.9e-110 366.9 0.0 1.7e-109 365.8 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 OAF99116.1 - 2.8e-43 148.2 0.1 7.4e-43 146.9 0.1 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 OAF99116.1 - 3.4e-40 138.1 8.1 1.2e-31 110.3 0.4 3.8 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 OAF99116.1 - 1.8e-24 86.4 0.0 7.2e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 OAF99116.1 - 9.6e-05 22.8 0.0 0.00081 19.9 0.0 2.6 2 1 0 2 2 2 1 PH domain KIF1B PF12423.8 OAF99116.1 - 0.00014 22.3 1.1 0.00047 20.5 1.1 2.0 1 0 0 1 1 1 1 Kinesin protein 1B UPF0242 PF06785.11 OAF99116.1 - 3.1 7.9 18.9 4 7.5 9.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3987 PF13148.6 OAF99116.1 - 4.3 6.3 14.6 43 3.0 10.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) MBF1 PF08523.10 OAF99117.1 - 0.12 12.9 1.0 0.3 11.6 1.0 1.7 1 1 0 1 1 1 0 Multiprotein bridging factor 1 Peptidase_M24_C PF16188.5 OAF99117.1 - 0.51 10.4 5.7 0.4 10.8 0.8 2.8 2 1 1 3 3 3 0 C-terminal region of peptidase_M24 F-box-like_2 PF13013.6 OAF99119.1 - 0.061 13.3 0.1 0.21 11.6 0.0 1.9 2 1 0 2 2 2 0 F-box-like domain DUF3752 PF12572.8 OAF99120.1 - 7.6e-49 166.1 12.3 7.6e-49 166.1 12.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Dynamitin PF04912.14 OAF99120.1 - 0.0057 16.0 2.5 0.0076 15.6 2.5 1.2 1 0 0 1 1 1 1 Dynamitin Vps8 PF12816.7 OAF99121.1 - 1.3e-56 191.3 0.1 4.3e-56 189.6 0.1 2.0 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OAF99121.1 - 1.3e-05 25.1 0.2 0.0012 18.7 0.1 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS Syntaxin-18_N PF10496.9 OAF99121.1 - 0.028 14.7 0.3 0.078 13.2 0.3 1.8 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus FAM220 PF15487.6 OAF99121.1 - 4.3 6.9 5.5 4.1 7.0 3.5 1.9 2 0 0 2 2 2 0 FAM220 family Peptidase_M13_N PF05649.13 OAF99123.1 - 3.7e-86 290.2 0.2 4.8e-86 289.8 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OAF99123.1 - 1.1e-62 211.4 0.0 2.3e-62 210.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M64 PF09471.10 OAF99123.1 - 0.13 11.8 0.3 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 IgA Peptidase M64 p450 PF00067.22 OAF99125.1 - 7.3e-42 143.7 0.0 1e-41 143.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM219A PF15260.6 OAF99125.1 - 0.066 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein family FAM219A DUF4686 PF15742.5 OAF99126.1 - 0.18 10.9 48.2 0.18 10.9 20.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4686) TMP_2 PF06791.13 OAF99126.1 - 3.8 7.1 8.9 5.5 6.6 5.2 2.3 2 1 0 2 2 2 0 Prophage tail length tape measure protein DUF948 PF06103.11 OAF99126.1 - 3.8 7.8 9.8 1.3 9.3 0.7 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) PI-PLC-X PF00388.19 OAF99129.1 - 5.4e-62 207.7 0.0 9.8e-62 206.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAF99129.1 - 2.8e-39 134.0 0.0 5e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAF99129.1 - 1.4e-05 25.4 0.0 3.6e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 C2 domain Cupin_2 PF07883.11 OAF99130.1 - 0.00052 19.7 0.2 0.00061 19.4 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 OAF99130.1 - 0.054 13.4 0.1 0.083 12.8 0.1 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain AraC_binding PF02311.19 OAF99130.1 - 0.081 12.8 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain RNA_pol_Rbc25 PF08292.12 OAF99131.1 - 1.8e-33 115.5 1.7 4.4e-33 114.3 1.7 1.6 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OAF99131.1 - 8.2e-14 51.7 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAF99131.1 - 0.015 15.6 0.1 0.035 14.5 0.0 1.6 2 0 0 2 2 2 0 S1 RNA binding domain NUFIP1 PF10453.9 OAF99132.1 - 1.3e-07 31.3 0.1 3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) GRIN_C PF15235.6 OAF99132.1 - 0.058 13.6 1.8 0.15 12.3 1.0 2.2 1 1 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus Nucleo_P87 PF07267.11 OAF99132.1 - 0.19 10.6 4.4 0.34 9.7 4.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 WD40 PF00400.32 OAF99133.1 - 6.5e-08 33.1 6.4 0.089 13.7 0.2 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ATP-synt_E PF05680.12 OAF99134.1 - 1.3e-21 76.8 0.0 1.5e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain Dynamin_M PF01031.20 OAF99135.1 - 6.6e-108 360.3 0.0 1.3e-107 359.3 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OAF99135.1 - 1.7e-56 190.9 0.3 3.7e-56 189.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAF99135.1 - 9.5e-32 109.0 2.1 2.6e-31 107.6 2.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAF99135.1 - 6.4e-05 23.0 0.3 0.00095 19.2 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase But2 PF09792.9 OAF99137.1 - 5.6e-48 163.0 3.9 5.6e-48 163.0 3.9 2.5 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain PBP PF01161.20 OAF99138.1 - 1.9e-19 70.3 0.0 2.7e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GPI-anchored PF10342.9 OAF99140.1 - 1.8e-15 57.5 0.3 1.8e-15 57.5 0.3 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CBM_48 PF02922.18 OAF99140.1 - 0.037 14.4 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cytochrom_B562 PF07361.11 OAF99141.1 - 0.095 13.4 0.1 0.11 13.1 0.1 1.1 1 0 0 1 1 1 0 Cytochrome b562 SET PF00856.28 OAF99142.1 - 7.4e-11 42.7 0.2 2.6e-10 41.0 0.2 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OAF99142.1 - 1.3e-07 31.5 14.1 1.3e-07 31.5 14.1 2.5 2 1 1 3 3 3 1 MYND finger MAS20 PF02064.15 OAF99142.1 - 0.1 12.7 0.5 0.21 11.7 0.5 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Glyco_transf_34 PF05637.12 OAF99144.1 - 1.1e-26 94.1 3.8 7.8e-25 88.0 3.8 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 OAF99144.1 - 0.003 17.6 1.1 0.0055 16.7 1.0 1.6 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DEC-1_N PF04625.13 OAF99144.1 - 1.4 7.8 6.6 0.76 8.7 4.7 1.5 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region zf-GRF PF06839.12 OAF99145.1 - 2.8e-06 27.3 4.6 6e-06 26.3 4.6 1.5 1 0 0 1 1 1 1 GRF zinc finger E1-E2_ATPase PF00122.20 OAF99146.1 - 6.2e-49 166.0 0.1 6.2e-49 166.0 0.1 2.3 2 1 1 3 3 3 1 E1-E2 ATPase HMA PF00403.26 OAF99146.1 - 5.6e-38 129.2 2.5 2.7e-14 53.4 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 OAF99146.1 - 4.5e-35 121.8 0.5 1e-34 120.6 0.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAF99146.1 - 0.00054 19.8 0.5 0.0042 16.9 0.1 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAF99146.1 - 0.0023 18.4 0.1 0.0094 16.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NPA PF16469.5 OAF99146.1 - 0.16 12.6 0.8 4.4 7.9 0.7 2.6 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 Peptidase_S8 PF00082.22 OAF99148.1 - 4.7e-32 111.4 14.6 1e-31 110.3 14.6 1.5 1 1 0 1 1 1 1 Subtilase family Sortilin-Vps10 PF15902.5 OAF99149.1 - 5.9e-281 931.7 28.2 7.6e-151 502.9 11.4 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OAF99149.1 - 1.7e-91 305.1 15.8 4.7e-47 160.5 0.9 2.6 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 OAF99149.1 - 4.1e-08 32.1 29.5 1.3 9.3 0.2 10.1 9 1 1 10 10 10 4 BNR/Asp-box repeat PSII_BNR PF14870.6 OAF99149.1 - 4.4e-07 29.5 4.6 0.0039 16.5 0.1 4.0 4 0 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 UCR_UQCRX_QCR9 PF05365.12 OAF99149.1 - 0.05 13.5 0.3 2.4 8.2 0.0 3.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like POC3_POC4 PF10448.9 OAF99149.1 - 0.1 12.6 0.6 0.3 11.1 0.1 2.0 2 0 0 2 2 2 0 20S proteasome chaperone assembly proteins 3 and 4 Ank_4 PF13637.6 OAF99150.1 - 7.2e-16 58.3 0.6 3.1e-07 30.8 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAF99150.1 - 6.7e-12 45.3 2.3 0.0016 18.8 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 OAF99150.1 - 1e-10 42.1 0.1 1.1e-09 38.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAF99150.1 - 3.8e-09 36.6 1.2 0.0026 18.0 0.2 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAF99150.1 - 8.7e-09 34.9 0.7 0.024 15.2 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat RRM_1 PF00076.22 OAF99151.1 - 2.1e-15 56.3 0.9 1.9e-10 40.4 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAF99151.1 - 0.11 12.7 0.0 0.65 10.2 0.0 2.3 2 1 0 2 2 2 0 RNA recognition motif Sds3 PF08598.11 OAF99152.1 - 3.2e-13 50.2 0.3 3.2e-13 50.2 0.3 1.8 2 0 0 2 2 2 1 Sds3-like DUF1487 PF07368.11 OAF99152.1 - 0.04 13.4 0.6 0.082 12.3 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF4094 PF13334.6 OAF99152.1 - 0.27 11.7 1.3 5.1 7.6 0.0 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4094) Abhydrolase_3 PF07859.13 OAF99153.1 - 0.0023 17.8 0.0 0.0089 15.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 OAF99154.1 - 1.2e-67 228.2 0.2 2.5e-67 227.1 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 OAF99154.1 - 1e-63 215.4 0.0 2.1e-63 214.3 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAF99154.1 - 3.4e-61 206.3 0.1 2e-60 203.8 0.1 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 OAF99154.1 - 5.9e-47 160.7 0.5 1.1e-46 159.8 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAF99154.1 - 2.8e-28 98.3 2.8 2.8e-28 98.3 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAF99154.1 - 1.6e-24 86.5 0.0 3.4e-23 82.3 0.0 3.0 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OAF99154.1 - 1.5e-09 37.6 0.0 3.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 OAF99154.1 - 8.4e-08 33.3 0.0 9e-07 30.0 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAF99154.1 - 0.00019 21.3 0.2 0.00044 20.1 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 OAF99154.1 - 0.00047 20.5 0.0 0.0019 18.5 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 OAF99154.1 - 0.0025 17.2 0.1 0.0064 15.9 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 OAF99154.1 - 0.0092 15.8 0.3 0.031 14.1 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2834 PF11196.8 OAF99155.1 - 0.14 12.5 16.2 0.04 14.3 2.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) Pyr_redox_3 PF13738.6 OAF99156.1 - 1.3e-14 54.2 0.0 2.6e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAF99156.1 - 2.6e-10 39.3 0.0 5.5e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAF99156.1 - 1.2e-08 34.5 0.0 7.9e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAF99156.1 - 5.8e-07 29.6 0.0 0.017 15.1 0.0 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAF99156.1 - 4.8e-05 23.5 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAF99156.1 - 5.1e-05 22.6 0.0 0.00028 20.1 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAF99156.1 - 7.6e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAF99156.1 - 0.0051 15.6 0.0 1.6 7.4 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 OAF99156.1 - 0.0072 15.9 0.0 13 5.3 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAF99156.1 - 0.0093 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 OAF99156.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3237 PF11578.8 OAF99157.1 - 1.2e-25 90.1 0.0 1.4e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Fungal_trans PF04082.18 OAF99158.1 - 2.8e-11 43.0 0.3 1.6e-10 40.5 0.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 OAF99159.1 - 1.1e-19 70.5 0.2 4.3e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 OAF99160.1 - 2.5e-18 66.5 0.1 2e-17 63.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAF99160.1 - 1.5e-07 31.0 0.4 0.00018 20.8 0.0 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAF99160.1 - 3.8e-07 29.6 1.5 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAF99160.1 - 1.5e-06 27.8 0.4 5.3e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAF99160.1 - 0.0013 18.9 1.4 0.0065 16.7 0.5 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAF99160.1 - 0.003 17.6 1.9 0.014 15.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAF99160.1 - 0.0035 16.5 1.4 0.0059 15.7 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAF99160.1 - 0.0076 15.3 2.9 0.033 13.3 2.9 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAF99160.1 - 0.014 15.0 8.0 0.036 13.7 2.3 2.7 2 1 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 OAF99160.1 - 0.068 12.2 0.8 4.8 6.2 1.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAF99160.1 - 0.083 11.6 2.0 4.5 5.9 1.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 OAF99160.1 - 0.31 9.8 1.2 5.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.25 OAF99161.1 - 1.6e-44 151.7 2.7 2.1e-44 151.4 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99161.1 - 1.3e-28 100.1 1.9 1.7e-28 99.8 1.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 OAF99161.1 - 5.1e-07 29.5 1.1 0.0003 20.4 1.4 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 OAF99161.1 - 1.7e-06 28.1 1.7 2.4e-06 27.6 1.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAF99161.1 - 3.6e-06 27.0 0.1 1.1e-05 25.4 0.3 1.7 2 0 0 2 2 2 1 NAD(P)H-binding DUF1776 PF08643.10 OAF99161.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAF99161.1 - 0.00066 19.2 0.3 0.001 18.6 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 OAF99161.1 - 0.0012 18.8 1.7 0.0012 18.8 1.7 2.4 2 1 1 3 3 3 1 Zinc-binding dehydrogenase F420_oxidored PF03807.17 OAF99161.1 - 0.0054 17.3 0.2 0.015 15.9 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 OAF99161.1 - 0.0088 15.4 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain RACo_C_ter PF14574.6 OAF99161.1 - 0.019 14.0 0.7 0.034 13.2 0.8 1.4 1 1 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain RmlD_sub_bind PF04321.17 OAF99161.1 - 0.055 12.6 0.7 0.072 12.2 0.7 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 OAF99161.1 - 0.062 13.2 0.3 0.19 11.6 0.4 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 OAF99162.1 - 1.2e-22 80.5 0.0 1.4e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 OAF99164.1 - 2.8e-58 197.6 0.0 3.9e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAF99164.1 - 4.1e-30 105.2 0.0 7.3e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAF99164.1 - 5.2e-05 23.0 0.8 0.0011 18.6 0.8 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAF99164.1 - 0.00048 20.3 0.0 0.0019 18.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAF99164.1 - 0.0029 16.9 0.0 0.18 11.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAF99164.1 - 0.0076 15.5 0.4 0.35 10.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAF99164.1 - 0.0087 15.2 0.1 0.031 13.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAF99164.1 - 0.064 12.3 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 OAF99164.1 - 0.12 12.6 0.1 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_2 PF00891.18 OAF99166.1 - 3.5e-25 88.5 0.0 9.1e-25 87.2 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAF99166.1 - 0.00088 19.9 0.0 0.0024 18.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAF99166.1 - 0.0092 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAF99166.1 - 0.035 14.8 0.0 0.35 11.6 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain CRIM PF16978.5 OAF99167.1 - 3e-40 137.6 0.0 7.9e-40 136.3 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 OAF99167.1 - 2.2e-29 101.9 0.8 3.6e-29 101.2 0.8 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 OAF99167.1 - 0.0065 16.7 0.0 0.035 14.3 0.0 2.2 2 0 0 2 2 2 1 TUG ubiquitin-like domain PBP1_TM PF14812.6 OAF99167.1 - 2.5 8.5 6.9 0.43 11.0 2.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRCC PF10253.9 OAF99168.1 - 2.5e-28 100.3 15.1 2.5e-28 100.3 15.1 2.5 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF4741 PF15897.5 OAF99169.1 - 0.37 10.6 3.9 0.36 10.6 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4741) adh_short PF00106.25 OAF99170.1 - 6.8e-26 90.9 0.0 8.9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99170.1 - 1.3e-14 54.3 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAF99170.1 - 0.00048 20.1 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAF99170.1 - 0.0007 19.6 0.0 0.0016 18.4 0.0 1.6 2 0 0 2 2 2 1 KR domain Fungal_trans_2 PF11951.8 OAF99171.1 - 1.8e-28 99.4 5.3 2.5e-28 99.0 5.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF99171.1 - 8.5e-06 25.8 8.9 2e-05 24.6 8.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAF99172.1 - 4.2e-19 69.4 0.1 6.8e-19 68.7 0.1 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3500 PF12006.8 OAF99173.1 - 3.9e-105 351.6 0.0 4.8e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) B12-binding PF02310.19 OAF99174.1 - 6.5e-05 23.0 0.0 9.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain TmoB PF06234.12 OAF99174.1 - 0.09 12.9 0.1 0.19 11.8 0.1 1.5 1 1 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) Tannase PF07519.11 OAF99175.1 - 4.3e-107 358.9 1.3 5.9e-107 358.5 1.3 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 OAF99175.1 - 0.0058 15.9 0.0 0.039 13.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 OAF99176.1 - 8.8e-14 51.5 0.2 6.5e-08 32.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAF99176.1 - 3e-08 33.3 0.1 0.00057 19.2 0.7 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAF99176.1 - 1.7e-07 31.4 0.4 4.6e-07 30.0 0.3 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAF99176.1 - 9.9e-07 28.6 1.7 0.00012 21.8 1.9 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAF99176.1 - 0.00034 19.8 0.7 0.00062 19.0 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.21 OAF99176.1 - 0.07 12.5 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 OAF99176.1 - 0.12 11.6 1.5 0.2 10.9 1.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAF99176.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAF99176.1 - 0.14 11.7 0.4 0.45 10.1 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 OAF99176.1 - 0.17 11.1 0.6 0.29 10.4 0.6 1.3 1 0 0 1 1 1 0 Thi4 family F420_oxidored PF03807.17 OAF99176.1 - 0.17 12.5 2.6 0.49 11.0 0.7 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 OAF99176.1 - 0.19 10.8 0.7 0.26 10.3 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAF99176.1 - 0.22 10.4 0.2 0.35 9.7 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.16 OAF99177.1 - 5.2e-38 130.9 27.4 8.2e-38 130.2 27.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF99177.1 - 1.6e-08 33.8 33.0 2.7e-08 33.1 12.8 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MMPL PF03176.15 OAF99177.1 - 0.1 11.5 0.1 0.1 11.5 0.1 2.5 3 1 0 3 3 3 0 MMPL family Fungal_trans PF04082.18 OAF99178.1 - 8.5e-05 21.7 1.0 0.00016 20.8 0.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF99178.1 - 0.0037 17.3 10.6 0.011 15.8 10.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAF99179.1 - 5.2e-29 101.1 0.0 6.9e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99179.1 - 1e-18 67.8 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAF99179.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Acetyltransf_10 PF13673.7 OAF99180.1 - 5.1e-09 36.1 0.0 8.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAF99180.1 - 2.9e-06 27.6 0.0 5.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAF99180.1 - 3.2e-06 27.4 0.0 4.5e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 OAF99180.1 - 0.015 15.4 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAF99180.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SmpA_OmlA PF04355.13 OAF99180.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 SmpA / OmlA family Acetate_kinase PF00871.17 OAF99181.1 - 3.6e-96 322.2 0.0 4.2e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family USP7_ICP0_bdg PF12436.8 OAF99181.1 - 0.19 11.0 0.0 0.51 9.6 0.0 1.6 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 Isochorismatase PF00857.20 OAF99182.1 - 5.2e-31 108.2 0.1 6.8e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family DDE_Tnp_IS1595 PF12762.7 OAF99182.1 - 0.031 14.3 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain PAP_assoc PF03828.19 OAF99184.1 - 5.3e-19 68.2 0.0 1.3e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAF99184.1 - 4.4e-06 26.9 0.0 8.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAF99184.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Striatin PF08232.12 OAF99184.1 - 7.7 7.1 20.5 0.21 12.2 0.3 3.1 2 0 0 2 2 2 0 Striatin family ERGIC_N PF13850.6 OAF99185.1 - 0.13 12.6 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COesterase PF00135.28 OAF99187.1 - 3.7e-94 316.4 0.0 5e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAF99187.1 - 7.8e-06 25.9 0.1 9e-05 22.4 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAF99187.1 - 0.06 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family EVE PF01878.18 OAF99188.1 - 5.5e-46 156.2 0.0 8.1e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 EVE domain PBP1_TM PF14812.6 OAF99188.1 - 0.9 10.0 6.5 0.36 11.2 0.2 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_clus PF00172.18 OAF99189.1 - 5.9e-08 32.7 11.3 8.2e-08 32.3 11.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MetOD2 PF18548.1 OAF99189.1 - 0.0079 16.3 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Metanogen output domain 2 Glyco_transf_8 PF01501.20 OAF99190.1 - 1e-07 31.8 0.1 8.5e-07 28.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Sugar_tr PF00083.24 OAF99191.1 - 2.2e-96 323.5 24.5 1.6e-95 320.7 24.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99191.1 - 6.4e-23 81.2 53.7 3.2e-22 78.9 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 OAF99191.1 - 2.5 8.0 5.9 16 5.4 0.2 3.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ABC2_membrane_2 PF12679.7 OAF99191.1 - 7.1 5.8 11.4 10 5.3 7.5 2.6 1 1 1 2 2 2 0 ABC-2 family transporter protein zf-C2H2 PF00096.26 OAF99193.1 - 3.2e-05 24.1 2.5 0.074 13.5 0.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAF99193.1 - 0.0007 20.2 0.5 0.02 15.5 0.1 2.5 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 OAF99193.1 - 0.002 18.4 0.1 0.004 17.4 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 OAF99193.1 - 0.018 15.4 0.3 0.018 15.4 0.3 1.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_aberr PF17017.5 OAF99193.1 - 0.064 13.4 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 OAF99193.1 - 0.12 13.2 2.4 2.7 9.1 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 OAF99193.1 - 0.14 12.5 0.4 0.26 11.6 0.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding EccE PF11203.8 OAF99193.1 - 8.2 6.8 8.6 26 5.2 8.7 1.9 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE zf-C2H2 PF00096.26 OAF99194.1 - 2.9e-06 27.4 0.5 2.9e-06 27.4 0.5 1.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAF99194.1 - 3.4e-06 26.9 0.3 6e-06 26.1 0.3 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAF99194.1 - 3.2e-05 24.1 2.1 0.0014 18.9 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAF99194.1 - 6.9e-05 23.4 0.5 0.00013 22.5 0.5 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_12 PF18658.1 OAF99194.1 - 0.0016 18.0 0.7 0.0026 17.3 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-C2H2_11 PF16622.5 OAF99194.1 - 0.0052 16.5 0.2 0.0088 15.8 0.2 1.2 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-BED PF02892.15 OAF99194.1 - 0.0059 16.6 0.7 0.0088 16.0 0.7 1.3 1 0 0 1 1 1 1 BED zinc finger DUF629 PF04780.12 OAF99194.1 - 0.014 13.9 0.3 0.018 13.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 OAF99194.1 - 0.015 15.6 0.1 0.024 15.0 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OAF99194.1 - 0.038 14.4 1.2 0.047 14.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 OAF99194.1 - 0.061 13.1 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 OAF99194.1 - 0.28 11.5 0.9 1 9.8 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAF99195.1 - 0.00069 19.9 0.4 0.0012 19.1 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAF99195.1 - 0.0055 17.4 0.4 0.011 16.5 0.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAF99195.1 - 0.025 14.6 0.2 0.054 13.5 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAF99195.1 - 0.14 12.5 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAF99195.1 - 0.3 11.5 1.0 0.5 10.8 0.3 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OAF99196.1 - 1.1e-09 38.4 5.9 1.6e-09 37.9 5.9 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OAF99196.1 - 4.5e-08 33.1 13.8 4.1e-05 23.8 2.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAF99196.1 - 2e-06 28.1 12.0 0.00033 21.2 1.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 OAF99196.1 - 5.2e-06 26.4 6.1 6.7e-05 22.8 0.2 2.4 2 0 0 2 2 2 1 BED zinc finger GAGA PF09237.11 OAF99196.1 - 5.2e-06 26.2 1.1 0.08 12.8 0.4 2.3 1 1 1 2 2 2 2 GAGA factor zf-H2C2_2 PF13465.6 OAF99196.1 - 8.8e-06 25.9 11.7 8.2e-05 22.9 2.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 OAF99196.1 - 0.0018 18.0 4.1 0.0018 18.0 4.1 3.4 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-ISL3 PF14690.6 OAF99196.1 - 0.008 16.8 6.1 0.35 11.6 0.7 2.2 2 0 0 2 2 2 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_jaz PF12171.8 OAF99196.1 - 0.0082 16.4 3.4 0.031 14.6 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DZR PF12773.7 OAF99196.1 - 0.009 16.0 0.9 0.017 15.1 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-C2H2_2 PF12756.7 OAF99196.1 - 0.017 15.5 9.6 0.88 9.9 2.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TF_Zn_Ribbon PF08271.12 OAF99196.1 - 0.018 14.5 0.9 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_11 PF16622.5 OAF99196.1 - 0.033 13.9 0.7 0.32 10.8 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF1561 PF07598.11 OAF99196.1 - 0.064 11.5 0.0 0.082 11.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) TT_ORF2 PF02957.15 OAF99196.1 - 0.078 13.9 1.2 0.078 13.9 1.2 2.2 2 1 0 2 2 1 0 TT viral ORF2 DUF1059 PF06348.11 OAF99196.1 - 0.12 12.6 1.7 4 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zinc_ribbon_9 PF14369.6 OAF99196.1 - 0.16 12.2 2.2 3.9 7.8 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-ribbon_3 PF13248.6 OAF99196.1 - 0.17 11.4 2.7 0.95 9.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain FYDLN_acid PF09538.10 OAF99196.1 - 0.18 12.5 8.7 4 8.2 4.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) OrsD PF12013.8 OAF99196.1 - 0.2 12.1 7.8 0.57 10.6 1.0 2.3 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Zn_Tnp_IS1595 PF12760.7 OAF99196.1 - 0.33 11.0 8.9 13 5.8 8.8 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAF99196.1 - 0.34 11.1 5.4 1.5 9.0 5.1 2.0 1 1 1 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.14 OAF99196.1 - 0.37 10.8 3.3 1.1 9.4 3.3 1.9 1 1 0 1 1 1 0 Adenylate kinase, active site lid YdjO PF14169.6 OAF99196.1 - 0.37 10.6 1.9 0.89 9.3 0.3 2.2 1 1 1 2 2 2 0 Cold-inducible protein YdjO OrfB_Zn_ribbon PF07282.11 OAF99196.1 - 0.48 10.4 3.6 8.8 6.3 0.1 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Nucleo_P87 PF07267.11 OAF99196.1 - 0.6 8.9 1.0 0.55 9.0 1.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-C2H2_9 PF16293.5 OAF99196.1 - 0.6 10.0 3.7 1.7 8.5 0.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) FOXP-CC PF16159.5 OAF99196.1 - 0.75 10.5 4.5 10 6.9 0.6 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain NICE-1 PF15845.5 OAF99196.1 - 1.3 9.8 8.4 1 10.2 6.4 1.9 1 1 0 1 1 1 0 Cysteine-rich C-terminal 1 family zf-C2H2_12 PF18658.1 OAF99196.1 - 3.2 7.4 6.0 0.94 9.1 0.7 2.1 1 1 1 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_6 PF13912.6 OAF99196.1 - 7.1 6.8 9.6 4.6 7.4 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.12 OAF99196.1 - 10 4.5 6.9 14 4.1 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) FAD_binding_3 PF01494.19 OAF99198.1 - 1.4e-14 54.1 0.0 2.7e-08 33.5 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAF99198.1 - 1.1e-09 38.0 1.1 7.4e-06 25.4 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAF99198.1 - 2.2e-09 37.4 1.0 0.00014 21.6 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAF99198.1 - 3.5e-08 32.6 0.5 2e-05 23.5 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OAF99198.1 - 1.3e-07 31.1 0.9 3.3e-07 29.7 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAF99198.1 - 7.9e-07 28.6 0.3 4.6e-05 22.8 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAF99198.1 - 7.4e-06 25.6 0.5 2e-05 24.1 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAF99198.1 - 7.4e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAF99198.1 - 2.3e-05 23.6 0.1 4.2e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAF99198.1 - 0.00022 21.7 0.4 0.0091 16.5 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAF99198.1 - 0.00043 19.7 0.1 0.12 11.6 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAF99198.1 - 0.0027 16.6 1.4 0.11 11.3 0.3 2.2 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 OAF99198.1 - 0.0046 16.3 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAF99198.1 - 0.08 12.0 0.4 0.28 10.2 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_4 PF01565.23 OAF99199.1 - 1.2e-19 70.4 3.4 2e-19 69.7 3.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAF99199.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like TPP_enzyme_N PF02776.18 OAF99200.1 - 2.4e-45 154.2 0.1 6.4e-45 152.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAF99200.1 - 6.4e-27 94.2 0.1 1.9e-26 92.7 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAF99200.1 - 9.7e-20 70.7 0.0 1.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 OAF99200.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit RicinB_lectin_2 PF14200.6 OAF99201.1 - 3.9e-05 24.3 3.4 0.00044 20.9 1.0 2.9 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like SKG6 PF08693.10 OAF99201.1 - 0.011 15.2 0.7 0.011 15.2 0.7 2.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain SSP160 PF06933.11 OAF99201.1 - 0.02 13.1 9.9 0.024 12.9 9.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM154 PF15102.6 OAF99201.1 - 0.22 11.4 2.1 0.52 10.2 2.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family VPDSG-CTERM PF18205.1 OAF99201.1 - 1.9 8.4 5.1 3.5 7.5 5.1 1.4 1 0 0 1 1 1 0 VPDSG-CTERM motif Gram_pos_anchor PF00746.21 OAF99201.1 - 7 6.7 11.0 0.19 11.7 4.0 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Jacalin PF01419.17 OAF99202.1 - 0.00014 21.8 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain ChiW_Ig_like PF18683.1 OAF99202.1 - 0.09 13.0 0.9 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Chitinase W immunoglobulin-like domain Clr5 PF14420.6 OAF99203.1 - 1e-14 54.5 1.0 2.2e-14 53.4 1.0 1.6 1 0 0 1 1 1 1 Clr5 domain Ank_3 PF13606.6 OAF99203.1 - 5.3e-09 35.6 1.5 0.34 11.6 0.0 6.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OAF99203.1 - 7.9e-09 35.9 0.0 0.46 11.1 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAF99203.1 - 1.3e-08 35.3 0.0 0.00058 20.4 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAF99203.1 - 1.7e-08 34.6 0.5 1.2 9.8 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OAF99203.1 - 0.00017 21.8 0.8 21 5.6 0.0 4.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) MFS_1 PF07690.16 OAF99204.1 - 1.1e-31 110.0 45.6 1.5e-30 106.3 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF751 PF05421.11 OAF99204.1 - 7.6 7.3 11.6 9.9 7.0 0.2 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF751) PRP38 PF03371.15 OAF99206.1 - 1.4e-53 181.3 0.0 1.7e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Pkinase PF00069.25 OAF99208.1 - 3.3e-73 246.3 0.0 4.3e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF99208.1 - 5.2e-38 130.8 0.0 7.4e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAF99208.1 - 3.4e-06 26.6 0.1 7e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like HD PF01966.22 OAF99209.1 - 0.0038 17.4 0.0 0.0049 17.1 0.0 1.2 1 0 0 1 1 1 1 HD domain Ank_2 PF12796.7 OAF99210.1 - 1.5e-67 224.2 12.0 1.7e-10 41.3 0.0 15.3 10 5 3 14 14 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAF99210.1 - 8.7e-65 214.3 24.0 4e-05 24.1 0.1 22.9 17 5 6 23 23 23 14 Ankyrin repeats (many copies) Ank PF00023.30 OAF99210.1 - 2.4e-49 163.7 16.4 0.0011 19.3 0.0 21.7 22 1 0 22 22 22 11 Ankyrin repeat Ank_3 PF13606.6 OAF99210.1 - 6e-47 152.2 12.1 0.0037 17.6 0.0 22.3 23 3 2 25 25 22 7 Ankyrin repeat Ank_5 PF13857.6 OAF99210.1 - 3.9e-42 141.8 33.8 2e-05 24.7 0.1 17.9 15 6 1 16 16 16 9 Ankyrin repeats (many copies) NACHT PF05729.12 OAF99210.1 - 9.2e-09 35.4 0.0 6.9e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAF99210.1 - 0.0014 19.0 0.1 0.014 15.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAF99210.1 - 0.0026 18.0 0.1 0.021 15.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain EH_Signature PF15611.6 OAF99210.1 - 0.0044 16.5 0.4 0.0044 16.5 0.4 1.8 2 0 0 2 2 2 1 EH_Signature domain tRNA-synt_His PF13393.6 OAF99210.1 - 0.078 12.2 1.3 0.65 9.2 0.0 2.8 2 1 1 3 3 3 0 Histidyl-tRNA synthetase DUF2802 PF10975.8 OAF99210.1 - 0.19 11.9 0.9 2.3 8.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) DUF1772 PF08592.11 OAF99211.1 - 2.5e-31 108.8 0.0 6.4e-31 107.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4134 PF13572.6 OAF99212.1 - 0.032 14.5 0.9 0.057 13.7 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) DUF2207 PF09972.9 OAF99212.1 - 0.65 8.7 4.4 0.87 8.3 4.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SH3_1 PF00018.28 OAF99213.1 - 1.1e-14 53.8 0.1 2.6e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAF99213.1 - 2.8e-14 52.7 0.0 5.5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 OAF99213.1 - 2.5e-13 50.3 5.8 3.4e-13 49.8 5.8 1.2 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 OAF99213.1 - 1.4e-10 40.7 0.1 3e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 OAF99213.1 - 0.0029 18.1 1.7 0.0029 18.1 1.7 2.7 4 0 0 4 4 4 1 Proline rich region of Caskin proteins DUF2439 PF10382.9 OAF99214.1 - 2.1e-24 85.6 0.2 3.6e-24 84.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) CBP4 PF07960.11 OAF99214.1 - 0.26 11.1 3.4 0.089 12.6 0.3 1.8 2 0 0 2 2 2 0 CBP4 AKNA PF12443.8 OAF99215.1 - 0.035 14.8 0.0 0.084 13.5 0.0 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor LapA_dom PF06305.11 OAF99216.1 - 0.0029 17.4 1.4 2.8 7.8 0.1 2.7 3 0 0 3 3 3 2 Lipopolysaccharide assembly protein A domain DUF3278 PF11683.8 OAF99216.1 - 0.0086 16.2 0.3 1.4 9.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3278) Tetraspanin PF00335.20 OAF99216.1 - 0.1 12.3 4.8 0.17 11.5 0.9 2.1 1 1 2 3 3 3 0 Tetraspanin family UbiA PF01040.18 OAF99216.1 - 0.16 11.3 12.4 1.3 8.2 12.5 2.0 1 1 0 1 1 1 0 UbiA prenyltransferase family CcmD PF04995.14 OAF99216.1 - 0.46 10.6 5.1 1.9 8.6 0.1 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Tenui_PVC2 PF06656.11 OAF99218.1 - 0.049 11.5 0.3 0.06 11.2 0.3 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Amidase PF01425.21 OAF99219.1 - 9.7e-52 176.4 0.0 7.2e-51 173.5 0.0 2.0 1 1 1 2 2 2 1 Amidase Vps5 PF09325.10 OAF99220.1 - 4.7e-10 39.4 6.5 8e-10 38.7 6.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 OAF99220.1 - 7.1e-09 35.6 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 PX domain TPR_2 PF07719.17 OAF99220.1 - 0.03 14.4 0.1 4.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAF99220.1 - 0.067 13.0 0.1 1.6 8.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAF99220.1 - 0.16 12.2 0.2 0.57 10.4 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 GTP_EFTU PF00009.27 OAF99221.1 - 3.4e-56 189.9 0.0 5.1e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAF99221.1 - 7.2e-24 83.7 0.0 1.4e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAF99221.1 - 1.3e-15 57.2 0.0 2.4e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAF99221.1 - 1e-06 29.0 0.0 4.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 OAF99221.1 - 1e-05 25.3 0.0 0.00056 19.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV RF3_C PF16658.5 OAF99221.1 - 1.3e-05 25.0 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain HK PF02110.15 OAF99223.1 - 4.6e-69 232.5 3.4 1.2e-68 231.2 3.4 1.6 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 OAF99223.1 - 1.5e-55 187.4 1.4 1.5e-55 187.4 1.4 2.0 3 0 0 3 3 3 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 OAF99223.1 - 0.00023 20.7 0.5 0.00078 19.0 0.5 2.0 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 OAF99223.1 - 0.0021 17.5 0.4 0.01 15.2 0.4 2.2 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAF99223.1 - 0.0061 15.9 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ADH_zinc_N PF00107.26 OAF99223.1 - 0.12 12.3 2.8 0.35 10.8 0.5 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase eIF-5_eIF-2B PF01873.17 OAF99224.1 - 5e-39 132.8 0.0 1.2e-38 131.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 OAF99224.1 - 4.5e-20 71.6 3.6 7.6e-20 70.8 0.9 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon WD40 PF00400.32 OAF99225.1 - 1.2e-33 114.5 15.1 2.6e-07 31.2 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAF99225.1 - 1.2e-12 47.9 0.7 0.0064 16.8 0.0 5.5 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAF99225.1 - 0.0045 16.9 0.0 0.49 10.3 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 OAF99225.1 - 0.04 12.7 0.0 0.086 11.6 0.0 1.5 1 0 0 1 1 1 0 Nup133 N terminal like WD40_like PF17005.5 OAF99225.1 - 0.079 12.3 0.0 12 5.2 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain MBOAT PF03062.19 OAF99226.1 - 1.1e-21 77.6 12.8 1.1e-21 77.6 12.8 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OAF99226.1 - 1.1e-05 25.6 0.8 3.5e-05 24.0 0.8 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SLC35F PF06027.12 OAF99227.1 - 2.5e-97 326.0 24.8 3e-97 325.8 24.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 OAF99227.1 - 3.2e-09 36.2 4.5 4.8e-09 35.6 4.5 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OAF99227.1 - 1.7e-05 25.0 37.3 2.5e-05 24.5 16.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family HCV_env PF01539.17 OAF99227.1 - 2.7 7.6 6.8 0.2 11.3 1.1 1.9 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 Zip PF02535.22 OAF99228.1 - 2.2e-26 92.9 11.6 1.8e-25 89.9 11.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter CAP59_mtransfer PF11735.8 OAF99229.1 - 2.6e-70 236.9 0.0 3.3e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 LETM1 PF07766.13 OAF99229.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 LETM1-like protein YL1 PF05764.13 OAF99230.1 - 0.0085 16.2 8.8 0.01 16.0 8.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 OAF99230.1 - 0.02 13.2 8.8 0.024 12.9 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAF99230.1 - 0.02 13.1 6.1 0.025 12.8 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAF99230.1 - 0.34 8.9 8.2 0.43 8.6 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAGA-Tad1 PF12767.7 OAF99230.1 - 0.7 9.6 9.4 1.3 8.7 9.4 1.5 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RMP PF14996.6 OAF99230.1 - 1.1 9.5 3.8 1.7 8.9 3.8 1.3 1 0 0 1 1 1 0 Retinal Maintenance Apt1 PF10351.9 OAF99230.1 - 1.3 7.8 8.9 1.6 7.5 8.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.12 OAF99230.1 - 2 6.9 15.1 2.5 6.6 15.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.7 OAF99230.1 - 3.9 5.5 5.6 4.9 5.2 5.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 OAF99230.1 - 6.7 5.4 5.7 7.6 5.2 5.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2428 PF10350.9 OAF99231.1 - 3.8e-64 216.6 0.0 8.3e-64 215.5 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 OAF99231.1 - 2.9e-07 30.2 12.3 0.059 13.6 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 OAF99231.1 - 0.00045 20.5 0.9 4 7.9 0.0 5.1 5 1 1 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 OAF99231.1 - 0.025 15.1 1.8 1.1 9.8 0.1 3.9 3 0 0 3 3 3 0 HEAT-like repeat Amidohydro_1 PF01979.20 OAF99231.1 - 0.046 13.0 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase family PX PF00787.24 OAF99232.1 - 1.7e-16 60.2 0.0 5.6e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OAF99232.1 - 1.6e-10 40.9 10.1 5.8e-07 29.3 1.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like SPX PF03105.19 OAF99232.1 - 5.8 6.7 17.3 0.53 10.1 5.2 2.6 2 1 0 2 2 2 0 SPX domain HET PF06985.11 OAF99233.1 - 9.2e-33 113.6 0.0 1.8e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HDV_ag PF01517.18 OAF99234.1 - 0.18 11.6 4.6 2.9 7.7 0.8 2.0 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen zf-RING_2 PF13639.6 OAF99236.1 - 1.7e-08 34.6 3.6 1.7e-08 34.6 3.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 OAF99236.1 - 1.8e-07 31.3 1.6 1.8e-07 31.3 1.6 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAF99236.1 - 3.9e-05 23.4 3.7 3.9e-05 23.4 3.7 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAF99236.1 - 4.7e-05 23.3 1.0 4.7e-05 23.3 1.0 2.9 3 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAF99236.1 - 9.4e-05 22.2 2.2 9.4e-05 22.2 2.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAF99236.1 - 0.0002 21.2 1.2 0.0002 21.2 1.2 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAF99236.1 - 0.0002 21.2 4.9 0.0002 21.2 4.9 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAF99236.1 - 0.00021 21.1 11.0 0.00021 21.1 11.0 2.6 2 0 0 2 2 2 1 PHD-finger zf-ANAPC11 PF12861.7 OAF99236.1 - 0.012 15.7 0.5 0.012 15.7 0.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD_2 PF13831.6 OAF99236.1 - 3 7.5 15.0 0.033 13.7 6.9 2.0 2 0 0 2 2 2 0 PHD-finger Sacchrp_dh_NADP PF03435.18 OAF99237.1 - 4.7e-16 59.2 0.0 8.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAF99237.1 - 0.025 15.0 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HET PF06985.11 OAF99238.1 - 1.2e-13 51.7 3.4 3.7e-10 40.3 0.1 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 OAF99238.1 - 8.7e-13 48.0 0.1 1.4e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAF99238.1 - 0.00052 20.4 1.0 0.0034 17.8 0.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAF99238.1 - 0.0034 17.3 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAF99238.1 - 0.015 15.6 0.0 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 OAF99238.1 - 0.15 12.0 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Methyltransf_23 PF13489.6 OAF99241.1 - 8.1e-20 71.3 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAF99241.1 - 1.4e-13 51.4 0.0 3.6e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAF99241.1 - 2.1e-10 41.1 0.0 6.4e-10 39.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAF99241.1 - 4.6e-10 40.1 0.0 3.7e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAF99241.1 - 1.6e-09 37.7 0.0 2.9e-08 33.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAF99241.1 - 0.00029 20.4 0.0 0.0073 15.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 OAF99241.1 - 0.00064 19.9 0.0 0.0027 17.9 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 OAF99241.1 - 0.00069 19.1 0.0 0.0022 17.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 OAF99241.1 - 0.0042 16.4 0.0 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 OAF99241.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 OAF99241.1 - 0.028 13.8 0.0 0.07 12.5 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OAF99241.1 - 0.09 12.1 0.0 0.52 9.6 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OAF99241.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 OAF99242.1 - 3.3e-14 52.7 0.1 6.2e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 OAF99242.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain MKLP1_Arf_bdg PF16540.5 OAF99242.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 DHFR_1 PF00186.19 OAF99246.1 - 2.2e-26 92.5 0.0 1e-24 87.0 0.0 2.8 1 1 0 1 1 1 1 Dihydrofolate reductase Peptidase_M74 PF03411.13 OAF99246.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase SMK-1 PF04802.15 OAF99247.1 - 1.6e-78 263.0 5.5 1.6e-78 263.0 5.5 1.7 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 eIF3_subunit PF08597.10 OAF99247.1 - 0.34 10.8 4.5 0.19 11.6 1.3 2.2 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit NmrA PF05368.13 OAF99250.1 - 1.9e-38 132.4 0.0 2.9e-38 131.7 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAF99250.1 - 1.3e-11 44.7 0.1 2e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAF99250.1 - 8.7e-05 22.1 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAF99250.1 - 0.00012 21.2 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 OAF99250.1 - 0.054 13.8 0.0 0.083 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DXP_reductoisom PF02670.16 OAF99250.1 - 0.085 13.6 0.0 0.22 12.3 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Cas_Csy4 PF09618.10 OAF99252.1 - 0.095 12.8 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Abhydrolase_1 PF00561.20 OAF99253.1 - 9.9e-49 166.3 0.0 1.5e-47 162.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAF99253.1 - 0.0015 17.5 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 OAF99253.1 - 0.0024 18.5 1.1 0.0035 18.0 1.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAF99253.1 - 0.024 13.9 0.0 0.7 9.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ADH_zinc_N PF00107.26 OAF99254.1 - 1.4e-24 86.6 0.1 2.2e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAF99254.1 - 1.5e-20 73.1 0.5 2.8e-20 72.2 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAF99254.1 - 0.009 15.3 0.1 0.009 15.3 0.1 1.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAF99254.1 - 0.01 16.9 0.0 0.018 16.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 OAF99254.1 - 0.12 11.9 0.2 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ADH_N_2 PF16884.5 OAF99254.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DLH PF01738.18 OAF99256.1 - 2.2e-28 99.3 0.0 2.8e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LRR_4 PF12799.7 OAF99257.1 - 1.2e-31 108.2 24.9 3.2e-08 33.7 0.8 6.7 1 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAF99257.1 - 1e-19 70.0 24.8 1.4e-07 31.2 3.2 6.2 3 2 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 OAF99257.1 - 1.3e-12 47.5 9.5 4.4e-05 23.0 0.8 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 OAF99257.1 - 0.00019 21.2 12.6 10 6.5 0.1 7.0 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 OAF99257.1 - 0.016 15.7 17.4 24 6.0 0.1 8.0 8 2 0 8 8 8 0 Leucine Rich Repeat TMEM237 PF15383.6 OAF99258.1 - 0.53 9.3 6.6 0.84 8.7 6.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 ketoacyl-synt PF00109.26 OAF99259.1 - 3.4e-63 213.6 1.4 1.4e-61 208.2 0.2 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAF99259.1 - 4.6e-36 123.4 0.4 2e-35 121.3 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_C PF02803.18 OAF99259.1 - 2e-06 27.5 0.6 0.0016 18.1 0.1 3.5 3 1 0 3 3 3 2 Thiolase, C-terminal domain Thiolase_N PF00108.23 OAF99259.1 - 3.7e-05 23.2 0.1 0.00016 21.2 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain NicO PF03824.16 OAF99260.1 - 1.2e-63 215.2 11.8 1.2e-63 215.2 11.8 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein DHHC PF01529.20 OAF99260.1 - 8.7 6.5 14.8 3.4 7.8 0.3 3.4 2 1 1 3 3 3 0 DHHC palmitoyltransferase Pyr_redox_2 PF07992.14 OAF99261.1 - 1.4e-32 113.1 0.0 1.9e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAF99261.1 - 4.9e-11 43.0 0.2 2.8e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAF99261.1 - 1.3e-05 24.6 0.0 0.00018 20.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAF99261.1 - 0.00018 20.8 0.9 0.0016 17.6 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAF99261.1 - 0.0028 16.9 0.9 0.076 12.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 OAF99261.1 - 0.029 13.7 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase CoA_binding_2 PF13380.6 OAF99261.1 - 0.076 13.5 0.2 0.29 11.6 0.0 2.1 3 0 0 3 3 3 0 CoA binding domain HI0933_like PF03486.14 OAF99261.1 - 0.091 11.4 5.1 0.33 9.6 0.0 3.3 3 1 0 4 4 4 0 HI0933-like protein IBR PF01485.21 OAF99262.1 - 7e-15 55.0 17.5 7.1e-08 32.6 0.8 2.1 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-RING_7 PF02591.15 OAF99262.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 OAF99262.1 - 3.9 7.0 12.7 1 8.8 1.7 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Peptidase_M28 PF04389.17 OAF99264.1 - 7.8e-37 126.9 0.0 1.5e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAF99264.1 - 1.3e-10 41.1 0.6 4.3e-10 39.5 0.3 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 OAF99264.1 - 2.4e-06 27.4 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cutinase PF01083.22 OAF99265.1 - 4.4e-22 78.9 1.0 5.8e-22 78.5 1.0 1.1 1 0 0 1 1 1 1 Cutinase FSH1 PF03959.13 OAF99265.1 - 0.037 13.7 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) VirJ PF06057.11 OAF99265.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Na_K-ATPase PF00287.18 OAF99265.1 - 0.18 11.0 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Cutinase PF01083.22 OAF99266.1 - 1.3e-47 162.0 5.2 1.6e-47 161.8 5.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAF99266.1 - 0.0011 18.6 1.7 0.0013 18.4 1.0 1.6 1 1 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 OAF99266.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 OAF99266.1 - 0.0019 18.1 0.1 0.0029 17.5 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 OAF99266.1 - 0.0086 15.9 0.7 0.0099 15.7 0.7 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 OAF99266.1 - 0.01 15.7 2.5 0.012 15.5 1.3 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 OAF99266.1 - 0.037 13.6 0.2 0.056 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 OAF99266.1 - 0.038 12.9 0.2 0.057 12.3 0.2 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 OAF99266.1 - 0.09 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BolA PF01722.18 OAF99267.1 - 8.6e-12 45.2 0.0 2.6e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein DUF1455 PF07306.11 OAF99268.1 - 0.032 14.2 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) CBM_21 PF03370.13 OAF99273.1 - 2.1e-35 121.3 2.7 3.8e-35 120.5 2.7 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OAF99273.1 - 7.9e-09 36.0 1.9 1.7e-08 34.9 1.9 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Complex1_49kDa PF00346.19 OAF99273.1 - 0.16 11.1 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit EBP PF05241.12 OAF99274.1 - 7.1e-67 224.3 10.2 8.3e-67 224.1 10.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein CstA PF02554.14 OAF99274.1 - 0.017 14.0 0.8 0.027 13.4 0.8 1.2 1 0 0 1 1 1 0 Carbon starvation protein CstA RCDG1 PF15725.5 OAF99274.1 - 0.56 10.7 4.7 1.1 9.8 4.7 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein HET PF06985.11 OAF99275.1 - 1.3e-05 25.6 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S9 PF00326.21 OAF99276.1 - 0.0056 16.2 0.5 0.0098 15.4 0.3 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAF99276.1 - 0.11 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase MFS_1 PF07690.16 OAF99279.1 - 2.3e-38 132.0 37.4 2.3e-38 132.0 37.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF99279.1 - 7.1e-06 25.1 13.3 7.1e-06 25.1 13.3 3.0 4 1 0 4 4 4 1 Sugar (and other) transporter DUF5493 PF17597.2 OAF99279.1 - 0.62 10.4 0.1 0.62 10.4 0.1 4.0 3 2 0 4 4 4 0 Family of unknown function (DUF5493) DUF2304 PF10066.9 OAF99279.1 - 2.3 8.5 12.5 8.3 6.7 3.9 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Pkinase PF00069.25 OAF99281.1 - 3.9e-05 23.1 0.0 8.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF99281.1 - 5.4e-05 22.6 0.0 0.00033 20.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF892 PF05974.12 OAF99281.1 - 0.091 12.8 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Pkinase PF00069.25 OAF99282.1 - 4.8e-49 167.1 0.0 8.2e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF99282.1 - 3.1e-24 85.7 0.0 6.1e-24 84.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAF99282.1 - 0.00019 20.9 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAF99282.1 - 0.0029 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAF99282.1 - 0.041 12.8 0.0 0.089 11.7 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain HEAT PF02985.22 OAF99283.1 - 1.1e-06 28.3 0.1 1.9 9.0 0.0 5.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 OAF99283.1 - 5.2e-05 23.5 2.4 0.041 14.3 0.9 4.9 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 OAF99283.1 - 0.00052 20.1 0.4 5.5 7.0 0.0 4.6 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAF99283.1 - 0.016 13.8 0.0 3.4 6.1 0.0 3.7 4 1 0 4 4 4 0 Adaptin N terminal region HEAT_EZ PF13513.6 OAF99283.1 - 0.018 15.6 0.9 3.3 8.3 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Sec7_N PF12783.7 OAF99284.1 - 7.5e-05 22.7 1.0 0.92 9.4 0.1 4.4 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 OAF99284.1 - 0.00021 21.3 5.9 7.8 7.1 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat RTP1_C1 PF10363.9 OAF99284.1 - 0.021 15.0 0.0 0.17 12.1 0.0 2.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 SLATT_5 PF18160.1 OAF99286.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DNA_pol_B_thumb PF14791.6 OAF99287.1 - 7.5e-23 80.5 0.3 1.6e-22 79.4 0.3 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 OAF99287.1 - 1.6e-18 66.9 0.0 4e-18 65.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 OAF99287.1 - 2.6e-17 62.3 0.7 7e-17 61.0 0.7 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OAF99287.1 - 4.5e-08 33.3 0.2 4.7e-07 30.1 0.1 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 OAF99287.1 - 0.005 17.2 0.0 0.023 15.1 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 OAF99287.1 - 0.0063 17.1 0.0 0.035 14.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain MitMem_reg PF13012.6 OAF99288.1 - 7.8e-12 45.6 0.1 1.8e-11 44.5 0.1 1.6 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAF99288.1 - 7.3e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease U79_P34 PF03064.16 OAF99288.1 - 0.0035 16.7 0.3 0.0057 16.0 0.3 1.3 1 0 0 1 1 1 1 HSV U79 / HCMV P34 ADH_N PF08240.12 OAF99289.1 - 1.5e-27 95.7 0.4 2.7e-27 94.8 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAF99289.1 - 2e-17 63.4 0.2 5.6e-17 61.9 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAF99289.1 - 1.1e-06 28.3 0.2 0.0055 16.2 0.1 2.5 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 OAF99289.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 OAF99289.1 - 0.0056 16.0 0.6 0.011 15.0 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAF99289.1 - 0.033 14.1 0.2 0.054 13.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.25 OAF99289.1 - 0.04 13.3 0.3 0.064 12.7 0.3 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ADH_zinc_N_2 PF13602.6 OAF99289.1 - 0.071 14.2 0.0 0.2 12.7 0.0 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Abhydrolase_1 PF00561.20 OAF99290.1 - 7.4e-25 88.1 0.2 4e-24 85.7 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAF99290.1 - 2.9e-14 54.2 0.0 3.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAF99290.1 - 2.6e-12 46.5 0.0 6.1e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OAF99290.1 - 0.0021 17.8 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OAF99290.1 - 0.018 14.9 0.0 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 OAF99290.1 - 0.17 11.4 0.0 6.3 6.3 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family Pinin_SDK_memA PF04696.13 OAF99291.1 - 4.6e-27 94.6 17.7 4.6e-27 94.6 17.7 2.3 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region PHF5 PF03660.14 OAF99292.1 - 1.6e-51 172.8 10.4 1.8e-51 172.7 10.4 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OAF99292.1 - 0.37 8.6 7.2 0.39 8.5 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 OAF99292.1 - 3 7.9 16.6 5.9 7.0 2.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon Autophagy_N PF03986.13 OAF99293.1 - 6e-44 149.3 0.7 1e-43 148.5 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 OAF99293.1 - 5.9e-16 57.7 0.6 9.9e-16 56.9 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 OAF99293.1 - 8.6e-15 55.1 0.3 1.5e-14 54.3 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DIOX_N PF14226.6 OAF99294.1 - 4.2e-28 98.5 0.0 7e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAF99294.1 - 1.4e-12 48.0 0.0 3.7e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAF99295.1 - 6e-42 143.8 38.4 8.4e-42 143.3 38.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 OAF99295.1 - 0.0021 18.0 3.0 0.012 15.6 0.1 3.0 2 0 0 2 2 2 1 Bacteriophage P21 holin S MFS_1_like PF12832.7 OAF99295.1 - 0.0021 17.0 4.7 0.0021 17.0 4.7 1.9 2 1 0 2 2 2 1 MFS_1 like family SID-1_RNA_chan PF13965.6 OAF99295.1 - 0.9 7.9 5.3 4.3 5.6 2.4 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF1516 PF07457.11 OAF99295.1 - 7.8 6.8 8.1 3.8 7.7 1.6 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1516) DUF43 PF01861.16 OAF99296.1 - 0.092 11.9 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Sec61_beta PF03911.16 OAF99297.1 - 4.3e-17 61.9 1.5 6.5e-17 61.3 1.5 1.3 1 0 0 1 1 1 1 Sec61beta family Vta1_C PF18097.1 OAF99297.1 - 0.18 11.5 1.5 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Vta1 C-terminal domain Spt4 PF06093.13 OAF99299.1 - 0.041 14.0 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Ank_4 PF13637.6 OAF99302.1 - 3.7e-16 59.3 0.0 1e-07 32.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAF99302.1 - 1.7e-15 57.3 0.0 2.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAF99302.1 - 5.1e-14 51.0 0.0 0.00045 20.5 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OAF99302.1 - 8.9e-10 38.6 0.0 6e-05 23.3 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAF99302.1 - 0.0042 17.4 0.0 0.27 11.6 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Aldo_ket_red PF00248.21 OAF99304.1 - 3.5e-40 138.0 0.0 4.7e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 OAF99304.1 - 0.089 12.3 0.0 14 5.2 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family ADH_N_2 PF16884.5 OAF99305.1 - 4.7e-26 90.8 0.0 8.1e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAF99305.1 - 7.1e-23 81.0 0.7 1.5e-22 80.0 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAF99305.1 - 6.3e-08 33.8 0.0 1.2e-07 32.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase STALD PF18185.1 OAF99305.1 - 0.039 13.3 0.1 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Sir2- and TIR-associating SLOG family DAO PF01266.24 OAF99307.1 - 3.3e-33 115.7 0.0 4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAF99307.1 - 6.9e-05 23.2 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 OAF99307.1 - 0.00011 22.7 0.0 0.00038 20.9 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAF99307.1 - 0.00081 18.7 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAF99307.1 - 0.0036 16.6 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAF99307.1 - 0.0051 16.7 0.1 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 OAF99307.1 - 0.013 14.9 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Shikimate_DH PF01488.20 OAF99307.1 - 0.015 15.3 0.0 0.058 13.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAF99307.1 - 0.022 14.0 0.2 0.037 13.3 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 OAF99307.1 - 0.025 14.8 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 OAF99307.1 - 0.03 14.0 0.1 0.064 12.9 0.1 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 OAF99307.1 - 0.059 13.5 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_2 PF00890.24 OAF99307.1 - 0.088 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 OAF99307.1 - 0.19 11.2 0.0 0.52 9.8 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus AA_permease_2 PF13520.6 OAF99308.1 - 1.6e-56 192.0 46.7 1.9e-56 191.7 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAF99308.1 - 3.2e-30 105.2 35.6 4.3e-30 104.7 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AMPK1_CBM PF16561.5 OAF99311.1 - 1.6e-05 25.1 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Nucleoside_tran PF01733.18 OAF99314.1 - 2.4e-42 145.4 10.9 1.7e-40 139.3 10.9 2.3 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 OAF99314.1 - 2.6e-11 43.0 23.2 0.00036 19.6 0.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Iwr1 PF08574.10 OAF99315.1 - 1.1e-14 55.2 19.0 1.1e-14 55.2 19.0 2.6 2 0 0 2 2 2 1 Transcription factor Iwr1 Glyco_hydro_125 PF06824.11 OAF99316.1 - 3.9e-15 55.7 0.0 5.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Fungal_trans PF04082.18 OAF99317.1 - 1.1e-13 50.9 0.0 2.1e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF99317.1 - 0.0001 22.4 12.5 0.0001 22.4 12.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNOBA PF07701.14 OAF99317.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Heme NO binding associated ADH_N PF08240.12 OAF99318.1 - 3.4e-18 65.5 1.6 1.1e-17 63.8 1.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain HI0933_like PF03486.14 OAF99318.1 - 3.9e-05 22.5 0.0 5.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein ADH_zinc_N PF00107.26 OAF99318.1 - 0.00013 22.0 0.0 0.0011 19.0 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAF99318.1 - 0.00014 21.7 1.0 0.00035 20.4 1.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 3HCDH_N PF02737.18 OAF99318.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 OAF99318.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Cupin_1 PF00190.22 OAF99319.1 - 1.1e-06 28.3 0.1 1.7e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAF99319.1 - 3.6e-06 26.6 2.2 0.00022 20.9 2.2 2.4 1 1 0 1 1 1 1 Cupin domain Wzy_C PF04932.15 OAF99320.1 - 0.72 9.5 0.0 0.72 9.5 0.0 2.6 3 0 0 3 3 3 0 O-Antigen ligase DBINO PF13892.6 OAF99326.1 - 0.041 14.3 1.5 0.041 14.3 1.5 1.9 2 0 0 2 2 2 0 DNA-binding domain Tmemb_170 PF10190.9 OAF99327.1 - 7.1e-23 81.0 9.9 8.3e-23 80.8 9.9 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 CPP1-like PF11833.8 OAF99327.1 - 0.61 9.7 5.9 0.9 9.2 5.9 1.3 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like FtsX PF02687.21 OAF99327.1 - 4.2 7.9 13.5 0.81 10.2 8.1 2.0 1 1 1 2 2 2 0 FtsX-like permease family AhpC-TSA PF00578.21 OAF99330.1 - 2.2e-27 95.4 0.0 3.3e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAF99330.1 - 2e-11 43.8 0.0 4.9e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 OAF99330.1 - 2e-06 27.5 0.0 6.5e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PIN_8 PF18476.1 OAF99330.1 - 0.27 11.1 2.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 PIN like domain ATP11 PF06644.11 OAF99330.1 - 3.3 7.4 9.4 1.1 9.0 6.8 1.5 1 1 1 2 2 2 0 ATP11 protein zf-C3HC4_3 PF13920.6 OAF99331.1 - 4.5e-11 42.4 8.8 4.5e-11 42.4 8.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAF99331.1 - 5.3e-06 26.2 5.8 5.3e-06 26.2 5.8 2.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAF99331.1 - 0.00033 20.6 6.1 0.00033 20.6 6.1 2.4 3 0 0 3 3 3 1 zinc-RING finger domain DUF5553 PF17707.1 OAF99331.1 - 0.016 14.6 0.5 0.031 13.7 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5553) Ecl1 PF12855.7 OAF99333.1 - 7.7e-37 128.1 25.8 7.7e-37 128.1 25.8 2.8 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 OAF99333.1 - 0.0088 16.1 4.8 0.029 14.4 4.8 1.9 1 1 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 OAF99333.1 - 1.3 8.6 9.0 11 5.6 6.7 2.8 2 1 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 Methyltransf_16 PF10294.9 OAF99334.1 - 1.7e-20 73.4 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAF99334.1 - 1.7e-07 30.9 0.1 3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAF99334.1 - 2.6e-05 23.8 0.1 4.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAF99334.1 - 0.0011 19.6 0.0 0.0034 18.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAF99334.1 - 0.0069 16.2 0.1 0.015 15.1 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 OAF99334.1 - 0.021 15.6 0.0 0.047 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 OAF99334.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ribosomal_S24e PF01282.19 OAF99335.1 - 5e-35 119.3 0.3 7.2e-35 118.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e YL1 PF05764.13 OAF99336.1 - 2.3e-59 201.5 30.1 2.3e-59 201.5 30.1 1.5 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 OAF99336.1 - 2.1e-09 37.0 0.0 3.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Thioredoxin_3 PF13192.6 OAF99336.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain PUF PF00806.19 OAF99337.1 - 3.2e-26 89.5 0.0 5.8e-05 22.6 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 OAF99337.1 - 2.4e-12 46.5 0.0 4.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) mRNA_cap_enzyme PF01331.19 OAF99338.1 - 8.1e-47 159.6 0.0 1.4e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OAF99338.1 - 1.2e-28 99.9 0.0 2.1e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 OAF99338.1 - 5.9e-07 29.3 0.0 4.9e-05 23.1 0.0 2.6 1 1 1 2 2 2 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 OAF99338.1 - 0.006 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Ubiq_cyt_C_chap PF03981.12 OAF99339.1 - 8.3e-33 113.4 1.1 1.4e-32 112.7 1.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Cnd3 PF12719.7 OAF99341.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain PH_10 PF15411.6 OAF99345.1 - 1.3e-30 106.2 0.1 2.8e-30 105.1 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 OAF99345.1 - 6.5e-15 55.8 0.0 1e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OAF99345.1 - 1.4e-10 41.3 0.0 4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 OAF99345.1 - 2.7e-05 24.4 5.9 4.9e-05 23.6 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAF99345.1 - 0.00056 19.8 5.7 0.00099 19.0 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OAF99345.1 - 0.00058 19.4 2.8 0.00058 19.4 2.8 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 OAF99345.1 - 0.00093 19.0 5.0 0.0018 18.1 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAF99345.1 - 0.004 17.4 3.3 0.0088 16.3 3.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAF99345.1 - 0.0098 15.8 5.4 0.018 14.9 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAF99345.1 - 0.011 15.5 2.4 0.021 14.7 2.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAF99345.1 - 0.014 15.2 2.8 0.03 14.1 2.8 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING-like PF08746.11 OAF99345.1 - 0.015 15.6 5.1 0.027 14.8 5.1 1.4 1 0 0 1 1 1 0 RING-like domain PH PF00169.29 OAF99345.1 - 0.042 14.4 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 PH domain zf-UDP PF14569.6 OAF99345.1 - 0.13 12.4 0.5 0.23 11.6 0.5 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OAF99345.1 - 0.19 11.6 3.5 0.41 10.6 3.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAF99345.1 - 1.1 9.4 5.9 2.8 8.0 5.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger GRP PF07172.11 OAF99347.1 - 0.59 10.9 19.0 2.6 8.8 19.0 2.1 1 0 0 1 1 1 0 Glycine rich protein family Peptidase_M48 PF01435.18 OAF99348.1 - 2.9e-35 121.8 0.0 4.8e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 OAF99348.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF4360 PF14273.6 OAF99349.1 - 8.6e-21 74.6 3.9 1.6e-20 73.7 3.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4366 PF14283.6 OAF99350.1 - 0.0026 17.8 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Podoplanin PF05808.11 OAF99350.1 - 0.01 15.9 0.4 0.015 15.4 0.4 1.2 1 0 0 1 1 1 0 Podoplanin SSP160 PF06933.11 OAF99350.1 - 0.027 12.7 15.8 0.035 12.3 15.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gram_pos_anchor PF00746.21 OAF99350.1 - 1.3 9.0 6.6 0.71 9.9 3.8 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Alpha_GJ PF03229.13 OAF99350.1 - 1.9 9.0 17.3 5.2 7.7 15.1 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J MSA-2c PF12238.8 OAF99350.1 - 9.6 6.1 10.3 15 5.5 10.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CDH-cyt PF16010.5 OAF99351.1 - 1.8e-38 132.0 7.3 2e-38 131.9 7.3 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF829 PF05705.14 OAF99352.1 - 6.7e-55 186.6 0.0 7.7e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Mpv17_PMP22 PF04117.12 OAF99353.1 - 4e-16 59.0 0.3 8e-16 58.0 0.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Alpha-L-AF_C PF06964.12 OAF99354.1 - 3.5e-15 56.5 0.1 7.2e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain ADH_zinc_N PF00107.26 OAF99355.1 - 8.6e-12 45.2 0.0 1.6e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 OAF99356.1 - 2.8e-11 43.3 0.1 1.2e-10 41.2 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAF99356.1 - 1.5e-07 31.5 0.0 8.7e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAF99356.1 - 2.1e-06 27.0 0.0 8.6e-06 25.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAF99356.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAF99356.1 - 0.00059 19.3 0.1 0.00092 18.7 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAF99356.1 - 0.011 15.1 0.0 0.058 12.8 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase DUF4568 PF15132.6 OAF99356.1 - 0.063 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Polysacc_synt_2 PF02719.15 OAF99356.1 - 0.21 10.7 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 OAF99357.1 - 3.5e-09 36.4 0.2 2.3e-07 30.4 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAF99357.1 - 5.3e-06 26.2 0.3 0.0018 17.9 0.1 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAF99357.1 - 6.3e-06 25.6 0.0 0.01 15.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAF99357.1 - 0.0038 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAF99357.1 - 0.061 12.2 0.1 0.81 8.5 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 OAF99357.1 - 0.067 13.8 0.1 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 OAF99357.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Alpha_L_fucos PF01120.17 OAF99359.1 - 1.8e-29 103.3 1.8 2.6e-29 102.8 1.8 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 OAF99359.1 - 4.9e-09 36.4 0.1 4.9e-09 36.4 0.1 2.4 3 0 0 3 3 3 1 F5/8 type C domain BASP1 PF05466.12 OAF99360.1 - 0.33 10.9 11.4 0.52 10.3 11.4 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF1996 PF09362.10 OAF99361.1 - 8e-83 278.0 1.0 9.8e-83 277.7 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.11 OAF99362.1 - 8.7e-33 113.7 0.1 1.8e-32 112.7 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4632 PF15451.6 OAF99362.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Med22 PF06179.12 OAF99364.1 - 7.1e-05 23.0 0.3 0.00028 21.0 0.3 1.8 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Rop-like PF05082.13 OAF99364.1 - 0.0057 16.4 0.7 0.21 11.4 0.1 2.7 2 1 1 3 3 3 1 Rop-like MAPEG PF01124.18 OAF99365.1 - 1.1e-16 61.0 1.3 1.3e-16 60.7 1.3 1.1 1 0 0 1 1 1 1 MAPEG family GFA PF04828.14 OAF99366.1 - 1.5e-18 66.9 0.1 2.1e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF562 PF04763.12 OAF99366.1 - 0.085 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF562) zf-C3HC4_4 PF15227.6 OAF99366.1 - 0.086 13.0 3.5 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING C1_1 PF00130.22 OAF99366.1 - 0.29 11.1 4.9 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2040 PF09745.9 OAF99367.1 - 4.7e-34 117.0 30.3 4.7e-34 117.0 30.3 4.1 3 3 2 5 5 5 1 Coiled-coil domain-containing protein 55 (DUF2040) Glyco_hydro_11 PF00457.17 OAF99369.1 - 7.8e-80 266.7 18.0 9e-80 266.5 18.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 GHL10 PF02638.15 OAF99369.1 - 0.058 12.5 0.1 0.074 12.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 CagY_M PF07337.11 OAF99370.1 - 0.022 14.4 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 DC-EC Repeat Bac_luciferase PF00296.20 OAF99371.1 - 2.4e-56 191.4 0.9 3e-56 191.1 0.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Ferric_reduct PF01794.19 OAF99372.1 - 4.6e-21 75.2 13.9 4.6e-21 75.2 13.9 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAF99372.1 - 2.6e-13 50.4 0.1 1.6e-11 44.6 0.1 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAF99372.1 - 1.1e-09 38.3 0.0 2.3e-08 34.1 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAF99372.1 - 0.048 14.3 0.0 0.27 11.9 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Fungal_trans PF04082.18 OAF99373.1 - 3.4e-12 46.0 0.1 5.5e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF99373.1 - 8.4e-09 35.4 12.4 1.9e-08 34.3 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.14 OAF99374.1 - 9.3e-34 116.5 0.0 1.2e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Sugar_tr PF00083.24 OAF99375.1 - 4.7e-44 151.0 15.2 8.5e-29 100.7 5.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAF99375.1 - 2.7e-19 69.3 23.4 2.2e-18 66.3 22.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_J PF04911.12 OAF99375.1 - 0.097 12.3 0.7 0.56 9.8 0.1 2.3 2 0 0 2 2 2 0 ATP synthase j chain Bacillus_PapR PF05968.11 OAF99375.1 - 0.15 11.9 1.4 0.4 10.6 1.4 1.7 1 0 0 1 1 1 0 Bacillus PapR protein DUF4231 PF14015.6 OAF99375.1 - 0.6 10.6 2.7 1.3 9.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Mem_trans PF03547.18 OAF99377.1 - 8.7e-15 54.0 5.6 3e-14 52.2 5.6 1.7 1 1 0 1 1 1 1 Membrane transport protein DUF3333 PF11812.8 OAF99378.1 - 0.11 12.6 0.0 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) DUF155 PF02582.14 OAF99379.1 - 1.3e-51 175.2 0.9 1.9e-51 174.7 0.9 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PseudoU_synth_1 PF01416.20 OAF99380.1 - 1.8e-10 41.2 0.0 4.6e-09 36.7 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase TFIIE_alpha PF02002.17 OAF99381.1 - 5.4e-12 45.5 0.2 9.1e-12 44.8 0.2 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit RXT2_N PF08595.11 OAF99381.1 - 0.61 10.1 9.2 0.52 10.3 2.4 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 OAF99381.1 - 0.72 9.1 5.4 1.3 8.3 5.4 1.6 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 OAF99381.1 - 4.1 7.0 5.5 6.7 6.3 5.5 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Importin_rep_6 PF18829.1 OAF99381.1 - 4.3 7.5 7.6 4.5 7.5 4.0 2.6 3 0 0 3 3 3 0 Importin repeat 6 SRP_TPR_like PF17004.5 OAF99382.1 - 2.9e-20 72.5 3.4 1.3e-19 70.3 1.3 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 OAF99382.1 - 2.2e-13 50.4 8.3 2.2e-13 50.4 8.3 2.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.17 OAF99382.1 - 5.1e-07 29.3 15.9 0.0064 16.5 0.1 6.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAF99382.1 - 1.6e-06 28.2 9.1 0.22 12.2 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAF99382.1 - 2.4e-06 28.0 17.0 0.077 13.5 0.5 7.0 3 2 3 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAF99382.1 - 6e-06 26.4 7.3 0.0062 16.7 0.4 4.6 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAF99382.1 - 4.9e-05 23.8 24.0 0.81 10.7 0.2 8.0 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAF99382.1 - 0.00058 19.6 1.3 0.23 11.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAF99382.1 - 0.00068 19.7 5.6 37 4.9 0.0 6.4 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAF99382.1 - 0.009 16.3 15.9 1.1 9.5 0.2 5.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAF99382.1 - 0.011 16.0 4.2 2.6 8.6 0.1 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAF99382.1 - 0.022 15.4 20.1 0.51 11.0 1.3 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 OAF99382.1 - 0.041 14.4 0.4 0.33 11.5 0.0 2.8 3 1 0 3 3 2 0 Domain of unknown function (DUF4810) PPR PF01535.20 OAF99382.1 - 0.054 13.8 0.0 11 6.6 0.0 3.6 4 0 0 4 4 3 0 PPR repeat TPR_9 PF13371.6 OAF99382.1 - 0.076 13.2 10.6 11 6.3 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAF99382.1 - 0.4 10.6 12.4 18 5.4 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAF99382.1 - 0.65 10.4 11.0 1.9 8.9 1.0 4.1 4 3 1 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 OAF99382.1 - 0.68 10.4 15.7 0.2 12.1 0.4 4.4 5 0 0 5 5 4 0 Bacterial transcriptional activator domain SAP PF02037.27 OAF99383.1 - 0.13 12.1 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 SAP domain EST1_DNA_bind PF10373.9 OAF99384.1 - 1.7e-17 63.8 0.0 3.2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain zf-Di19 PF05605.12 OAF99384.1 - 0.05 13.9 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding MFS_1 PF07690.16 OAF99385.1 - 1.6e-28 99.7 30.3 1.3e-27 96.7 12.9 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF99385.1 - 4.8e-09 35.6 0.0 4.8e-09 35.6 0.0 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter DUF5326 PF17260.2 OAF99385.1 - 4.9 7.4 7.6 0.45 10.7 0.7 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5326) Glycos_transf_2 PF00535.26 OAF99386.1 - 8.6e-25 87.5 0.0 8e-24 84.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAF99386.1 - 6.1e-10 39.4 0.1 5.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAF99386.1 - 0.01 15.3 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF3697 PF12478.8 OAF99386.1 - 0.047 13.8 0.3 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Cyclase PF04199.13 OAF99387.1 - 8.2e-14 52.0 0.2 1.2e-13 51.5 0.2 1.3 1 0 0 1 1 1 1 Putative cyclase Cupin_6 PF12852.7 OAF99387.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cupin DDE_1 PF03184.19 OAF99388.1 - 6.8e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAF99389.1 - 9.2e-12 44.8 0.2 1.7e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 OAF99389.1 - 0.0035 17.1 1.2 0.37 10.7 0.1 2.4 2 0 0 2 2 2 2 Homeodomain-like domain TryThrA_C PF12319.8 OAF99389.1 - 0.0075 15.8 0.1 0.0092 15.5 0.1 1.1 1 0 0 1 1 1 1 Tryptophan-Threonine-rich plasmodium antigen C terminal Pyr_redox_2 PF07992.14 OAF99390.1 - 9.7e-09 34.9 0.0 1.1e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAF99390.1 - 7.1e-06 24.7 0.0 2.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAF99390.1 - 0.00014 22.0 0.1 0.00046 20.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAF99390.1 - 0.0014 18.0 0.2 0.0057 16.0 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 OAF99392.1 - 1.6e-08 33.9 30.7 1.6e-08 33.9 30.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAF99392.1 - 1.2e-05 25.1 5.2 1.2e-05 25.1 5.2 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 FMO-like PF00743.19 OAF99393.1 - 4.3e-17 61.7 0.1 1.9e-16 59.6 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAF99393.1 - 4.8e-11 42.7 0.0 5e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAF99393.1 - 3.3e-09 36.4 0.0 3.4e-08 33.1 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAF99393.1 - 2.5e-08 33.6 0.1 2.4e-07 30.3 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAF99393.1 - 2.2e-06 27.0 0.0 0.00047 19.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAF99393.1 - 4.5e-06 26.5 0.2 0.0029 17.2 0.0 2.8 1 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAF99393.1 - 0.003 17.5 0.0 1.4 8.9 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAF99393.1 - 0.0075 15.6 0.0 0.57 9.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAF99393.1 - 0.011 16.2 0.1 2 9.0 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAF99393.1 - 0.062 12.5 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FCH PF00611.23 OAF99393.1 - 0.091 13.1 0.0 6.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Bac_luciferase PF00296.20 OAF99394.1 - 2.6e-61 207.8 0.1 3.3e-61 207.4 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 OAF99394.1 - 0.059 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase PI3_PI4_kinase PF00454.27 OAF99395.1 - 4.6e-35 121.6 0.1 2.5e-34 119.2 0.0 2.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 OAF99395.1 - 2.3e-19 69.1 0.1 4.5e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 OAF99395.1 - 0.056 12.8 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Rho_N PF07498.12 OAF99396.1 - 0.028 14.3 0.2 0.056 13.4 0.2 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain EF-hand_1 PF00036.32 OAF99397.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAF99397.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OAF99397.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OAF99397.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OAF99397.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OAF99397.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAF99397.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OAF99397.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OAF99397.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 OAF99397.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 OAF99397.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 OAF99397.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 OAF99397.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 OAF99397.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 OAF99397.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 OAF99397.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 OAF99397.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 OAF99397.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 OAF99397.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 OAF99397.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 OAF99397.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 OAF99397.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 OAF99397.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 OAF99397.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 OAF99397.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 OAF99397.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein SNARE PF05739.19 OAF99398.1 - 1.5e-13 50.5 0.6 3e-13 49.5 0.6 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAF99398.1 - 8.4e-05 22.3 11.5 0.024 14.3 3.1 2.2 2 0 0 2 2 2 2 Syntaxin Syntaxin_2 PF14523.6 OAF99398.1 - 0.0097 16.3 8.2 0.11 12.9 3.1 2.3 2 0 0 2 2 2 2 Syntaxin-like protein DNA_repr_REX1B PF14966.6 OAF99398.1 - 0.076 13.7 2.2 0.14 12.9 0.5 2.3 2 1 1 3 3 3 0 DNA repair REX1-B MCPsignal PF00015.21 OAF99398.1 - 0.29 10.9 7.5 0.17 11.7 0.4 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.13 OAF99398.1 - 0.59 9.3 6.0 0.89 8.7 1.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein Peptidase_S8 PF00082.22 OAF99399.1 - 4.2e-27 95.2 4.0 4.2e-27 95.2 4.0 1.9 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 OAF99399.1 - 2.1e-08 34.7 0.0 1.7e-07 31.8 0.0 2.4 2 1 0 2 2 2 1 Peptidase inhibitor I9 Aminotran_3 PF00202.21 OAF99400.1 - 6.2e-107 357.7 0.2 7.7e-107 357.4 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAF99400.1 - 0.00022 20.5 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Glyco_hydro_3_C PF01915.22 OAF99401.1 - 2.3e-57 194.3 0.0 3.5e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAF99401.1 - 1.9e-46 158.9 0.0 3.4e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAF99401.1 - 1.3e-19 70.1 0.3 2.5e-19 69.1 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAF99401.1 - 1.4e-05 24.9 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 PA14 domain hnRNP_Q_AcD PF18360.1 OAF99401.1 - 0.025 14.5 0.0 0.15 12.0 0.0 2.3 3 0 0 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Sugar_tr PF00083.24 OAF99402.1 - 2.8e-79 267.1 28.3 3.2e-79 266.9 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99402.1 - 1.5e-13 50.4 36.0 7.6e-13 48.1 32.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily UCH PF00443.29 OAF99404.1 - 1e-37 130.1 0.1 1.8e-37 129.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 OAF99404.1 - 2.1e-28 99.2 0.4 9.1e-28 97.1 0.1 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3517) UCH_1 PF13423.6 OAF99404.1 - 3.6e-20 72.8 0.7 1e-19 71.3 0.0 2.2 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.11 OAF99405.1 - 0.00073 19.6 0.0 0.02 14.9 0.0 2.3 2 1 0 2 2 2 1 RNase P subunit Pop3 Senescence PF06911.12 OAF99405.1 - 0.04 14.2 0.0 0.06 13.7 0.0 1.2 1 0 0 1 1 1 0 Senescence-associated protein Sugar_tr PF00083.24 OAF99406.1 - 5.7e-58 196.9 22.8 6.7e-58 196.6 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99406.1 - 1.9e-22 79.7 34.4 1.9e-22 79.7 34.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAF99406.1 - 0.00014 20.8 13.2 0.0036 16.2 2.2 3.2 2 1 1 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 OAF99406.1 - 0.00044 18.9 9.4 0.00044 18.9 9.4 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein DUF5381 PF17353.2 OAF99406.1 - 0.85 9.4 4.5 0.67 9.7 1.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Abhydrolase_1 PF00561.20 OAF99407.1 - 1e-45 156.4 0.0 6.1e-45 153.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAF99407.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAF99407.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_hydro_61 PF03443.14 OAF99408.1 - 4.1e-51 173.8 0.2 4.9e-51 173.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 OAF99408.1 - 0.04 14.6 0.0 0.045 14.4 0.0 1.2 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF4382 PF14321.6 OAF99408.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) WD40 PF00400.32 OAF99409.1 - 1.4e-39 133.3 23.5 1.3e-07 32.2 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 OAF99409.1 - 6.4e-10 38.8 0.5 1.2e-09 37.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 OAF99409.1 - 1.9e-09 37.7 1.0 0.031 14.6 0.0 5.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAF99409.1 - 1.9e-06 26.8 3.3 2.6 6.6 0.0 5.9 1 1 5 6 6 6 3 Nucleoporin Nup120/160 F-box PF00646.33 OAF99409.1 - 2.7e-06 27.1 0.3 5.4e-06 26.1 0.3 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 OAF99409.1 - 0.00055 19.4 0.0 0.071 12.4 0.0 2.9 1 1 2 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 OAF99409.1 - 0.021 14.4 4.1 0.022 14.4 0.9 2.2 2 1 1 3 3 3 0 PQQ-like domain CDC45 PF02724.14 OAF99409.1 - 1.7 6.9 4.5 2.6 6.2 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein E1_dh PF00676.20 OAF99410.1 - 3e-115 384.3 0.4 3.6e-115 384.0 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAF99410.1 - 0.00058 19.2 0.2 0.0011 18.2 0.2 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Ferrochelatase PF00762.19 OAF99411.1 - 5.1e-99 331.4 0.0 5.9e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.16 OAF99412.1 - 5e-45 153.7 0.0 1.2e-44 152.4 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAF99412.1 - 2e-33 116.0 0.0 3.3e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 OAF99412.1 - 4.4e-24 85.0 1.5 4.4e-24 85.0 1.5 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 OAF99412.1 - 4.2e-09 35.9 0.3 2.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 SAP domain Amnionless PF14828.6 OAF99413.1 - 0.037 12.8 0.0 0.04 12.7 0.0 1.0 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 OAF99413.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Mucin15 PF15672.5 OAF99413.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 DDE_Tnp_1_4 PF13701.6 OAF99414.1 - 0.13 10.5 0.4 0.17 10.1 0.4 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 DUF3825 PF12873.7 OAF99417.1 - 1.6e-45 155.4 0.1 2e-45 155.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) Sugar_tr PF00083.24 OAF99418.1 - 3.9e-88 296.3 22.9 4.8e-88 296.0 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99418.1 - 1.2e-21 77.1 41.6 4.7e-16 58.6 20.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_YMGG PF13441.6 OAF99418.1 - 0.029 14.1 2.0 0.1 12.3 2.0 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 OAF99418.1 - 1.8 8.5 8.8 0.32 10.9 4.2 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain Zn_clus PF00172.18 OAF99419.1 - 2e-10 40.6 7.6 4e-10 39.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.6 OAF99420.1 - 3.9e-05 24.1 0.2 0.0038 17.8 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAF99420.1 - 0.00083 19.9 0.2 0.0091 16.6 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAF99420.1 - 0.0029 18.0 0.1 0.095 13.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAF99420.1 - 0.0044 17.3 0.1 0.036 14.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OAF99420.1 - 0.079 13.4 0.4 0.81 10.3 0.2 2.6 3 0 0 3 3 3 0 Ankyrin repeat Formyl_trans_N PF00551.19 OAF99422.1 - 6.9e-42 143.2 0.0 8.3e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Hat1_N PF10394.9 OAF99423.1 - 3.6e-36 124.8 1.2 9.3e-36 123.5 0.0 2.0 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 OAF99423.1 - 0.0054 17.0 0.0 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Zip PF02535.22 OAF99424.1 - 1.4e-33 116.5 25.1 2.4e-28 99.3 2.8 3.9 2 1 1 3 3 3 3 ZIP Zinc transporter Mito_carr PF00153.27 OAF99425.1 - 7e-47 157.3 4.3 1.9e-16 59.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP_transf PF09830.9 OAF99426.1 - 2.7e-09 37.0 0.0 5.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase Zn_clus PF00172.18 OAF99427.1 - 2.4e-09 37.2 11.3 4.4e-09 36.3 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAF99427.1 - 1.3e-05 24.4 0.0 2.6e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_1 PF00175.21 OAF99428.1 - 7.8e-28 97.3 0.0 1.2e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAF99428.1 - 1.4e-17 63.8 0.0 2.3e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAF99428.1 - 8e-06 26.1 0.1 0.061 13.4 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.16 OAF99429.1 - 1.6e-36 126.0 33.3 1.6e-36 126.0 33.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily NMO PF03060.15 OAF99430.1 - 2.1e-33 116.1 4.2 1.4e-25 90.4 4.0 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 OAF99430.1 - 1.2e-14 54.1 0.0 1.9e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAF99430.1 - 6.9e-08 31.9 1.2 9.7e-08 31.4 1.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAF99430.1 - 3.4e-06 26.4 0.2 5.2e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAF99430.1 - 0.011 15.2 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 OAF99430.1 - 0.072 12.4 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Trp_syntA PF00290.20 OAF99430.1 - 0.13 11.1 0.1 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Pkinase PF00069.25 OAF99431.1 - 6.7e-16 58.4 0.0 3.8e-15 56.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF99431.1 - 2.5e-07 30.3 0.0 5.5e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAF99431.1 - 0.026 14.4 0.2 0.44 10.4 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.18 OAF99432.1 - 7.6e-10 38.7 8.9 1.4e-09 37.9 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAF99432.1 - 3.6e-07 29.3 0.0 5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.28 OAF99433.1 - 4e-12 46.8 0.6 1.4e-09 38.6 0.0 3.1 3 1 0 3 3 3 2 SET domain DUF2072 PF09845.9 OAF99433.1 - 6.1 7.1 8.2 1.9 8.7 4.0 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein TackOD1 PF18551.1 OAF99433.1 - 6.5 6.4 8.6 1.3 8.7 1.6 2.8 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 Ribosomal_L14 PF00238.19 OAF99434.1 - 1.2e-48 164.2 3.0 1.4e-48 164.0 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 OAF99434.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q TFIIS_C PF01096.18 OAF99435.1 - 1.2e-11 44.3 4.3 1.2e-11 44.3 4.3 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OAF99435.1 - 1.8e-10 40.5 1.8 1.8e-10 40.5 1.8 2.9 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 OAF99435.1 - 0.00034 20.9 7.4 0.072 13.4 0.5 2.7 1 1 2 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Ogr_Delta PF04606.12 OAF99435.1 - 0.013 15.5 2.5 0.013 15.5 2.5 2.4 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger zf-CSL PF05207.13 OAF99435.1 - 0.064 13.0 9.2 0.53 10.1 0.8 2.4 2 1 0 2 2 2 0 CSL zinc finger TF_Zn_Ribbon PF08271.12 OAF99435.1 - 0.2 11.2 3.4 0.73 9.4 1.0 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding Rpr2 PF04032.16 OAF99435.1 - 0.24 11.7 6.8 1.2 9.5 0.7 2.7 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.6 OAF99435.1 - 0.27 10.7 5.1 0.3 10.5 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 OAF99435.1 - 0.31 11.0 12.7 3 7.8 0.8 3.4 2 1 0 2 2 2 0 Nudix N-terminal DZR PF12773.7 OAF99435.1 - 0.72 9.9 11.9 2.5e+02 1.8 11.9 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C4_Topoisom PF01396.19 OAF99435.1 - 0.92 9.4 5.9 0.6 9.9 0.6 2.6 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF3268 PF11672.8 OAF99435.1 - 1.3 9.4 6.8 0.23 11.8 1.8 2.1 2 1 0 2 2 2 0 zinc-finger-containing domain zf-ACC PF17848.1 OAF99435.1 - 1.4 9.1 8.4 21 5.3 0.7 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Lar_restr_allev PF14354.6 OAF99435.1 - 1.7 9.1 7.4 0.31 11.4 0.7 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 OAF99435.1 - 2.2 8.3 10.3 0.31 11.0 1.6 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.10 OAF99435.1 - 3.7 7.8 7.7 1.1 9.5 0.9 2.6 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Rotamase PF00639.21 OAF99436.1 - 1.2e-21 77.5 0.0 1.8e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OAF99436.1 - 1.8e-17 63.9 0.0 3.8e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OAF99436.1 - 3.4e-08 33.4 1.3 7.6e-08 32.3 1.3 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 OAF99436.1 - 3.4e-05 24.7 0.0 5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 OAF99436.1 - 0.12 13.0 0.0 0.21 12.3 0.0 1.3 1 0 0 1 1 1 0 X8 domain Corona_NS2 PF04753.12 OAF99437.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 PLRV_ORF5 PF01690.17 OAF99438.1 - 0.022 13.5 0.1 0.029 13.1 0.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PH PF00169.29 OAF99440.1 - 3.7e-09 37.0 0.0 1.2e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 OAF99440.1 - 5.7e-05 23.6 0.0 0.00018 22.0 0.0 1.9 1 0 0 1 1 1 1 Cell division protein anillin DEAD PF00270.29 OAF99441.1 - 4.4e-29 101.5 0.0 7.9e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAF99441.1 - 1.6e-20 73.5 0.0 7.1e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAF99441.1 - 0.00014 21.9 0.0 0.00097 19.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PRAI PF00697.22 OAF99441.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CCDC14 PF15254.6 OAF99442.1 - 0.5 8.9 4.3 0.65 8.6 4.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DUF2236 PF09995.9 OAF99443.1 - 3.6e-08 33.9 0.1 5.6e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Glyco_hydro_3_C PF01915.22 OAF99444.1 - 0.0063 16.5 0.0 0.0083 16.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain LPD11 PF18824.1 OAF99444.1 - 0.083 13.0 0.1 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Shadoo PF14999.6 OAF99445.1 - 8.3 6.5 11.0 4.6 7.4 8.6 1.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SnoaL_3 PF13474.6 OAF99447.1 - 9.8e-05 22.6 0.0 0.00011 22.4 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAF99447.1 - 0.0019 18.6 0.0 0.0021 18.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 OAF99447.1 - 0.003 17.7 0.0 0.0035 17.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAF99447.1 - 0.034 14.0 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase FAD_binding_3 PF01494.19 OAF99448.1 - 3.4e-20 72.6 0.0 4.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAF99448.1 - 6e-08 32.7 4.2 0.0039 16.8 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAF99448.1 - 2.4e-07 30.9 0.2 6.3e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAF99448.1 - 3.5e-07 29.7 0.0 6.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAF99448.1 - 0.00026 20.3 0.2 0.03 13.6 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAF99448.1 - 0.00096 18.0 0.6 0.016 14.0 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAF99448.1 - 0.002 17.3 1.8 0.002 17.3 1.8 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAF99448.1 - 0.0043 16.2 1.1 0.0064 15.6 0.4 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAF99448.1 - 0.0056 15.6 0.2 0.15 10.9 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase Amino_oxidase PF01593.24 OAF99448.1 - 0.016 14.5 0.2 1.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Rossmann-like PF10727.9 OAF99448.1 - 0.039 13.8 0.5 0.1 12.5 0.2 1.8 2 0 0 2 2 2 0 Rossmann-like domain 3HCDH_N PF02737.18 OAF99448.1 - 0.05 13.5 0.5 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAF99448.1 - 0.078 12.3 0.5 0.15 11.3 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAF99448.1 - 0.088 12.1 1.5 0.46 9.8 0.9 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAF99448.1 - 0.16 12.6 5.9 0.18 12.4 0.7 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CDI PF02234.19 OAF99448.1 - 0.24 11.6 0.8 0.68 10.2 0.4 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Nse4_C PF08743.10 OAF99449.1 - 1.3e-33 115.1 0.0 3.2e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OAF99449.1 - 2.8e-08 33.7 0.0 2.8e-08 33.7 0.0 2.7 3 0 0 3 3 3 1 Binding domain of Nse4/EID3 to Nse3-MAGE CDC45 PF02724.14 OAF99449.1 - 0.66 8.2 9.3 1.1 7.5 9.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 OAF99449.1 - 8.1 6.3 10.4 40 4.0 10.4 2.2 1 1 0 1 1 1 0 Sigma-70, non-essential region PI3Ka PF00613.20 OAF99450.1 - 1.4e-56 190.8 0.1 2.2e-56 190.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OAF99450.1 - 1.5e-41 142.9 0.0 9.6e-27 94.4 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OAF99450.1 - 1.8e-28 99.2 0.0 3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF3445 PF11927.8 OAF99451.1 - 2.4e-74 249.8 0.0 4.9e-74 248.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) ALIX_LYPXL_bnd PF13949.6 OAF99451.1 - 0.25 10.6 0.1 0.37 10.0 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Mcl1_mid PF12341.8 OAF99453.1 - 0.043 13.2 0.1 0.45 9.8 0.1 2.4 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region AA_permease PF00324.21 OAF99454.1 - 1.1e-42 146.2 28.5 1.9e-42 145.5 28.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAF99454.1 - 2.4e-26 92.5 21.5 3.2e-26 92.1 21.5 1.1 1 0 0 1 1 1 1 Amino acid permease Trypan_PARP PF05887.11 OAF99455.1 - 0.00032 20.7 6.1 0.00041 20.3 6.1 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) EpCAM_N PF18635.1 OAF99455.1 - 0.0048 17.0 0.1 8.4 6.7 0.0 3.0 3 0 0 3 3 3 2 Epithelial cell adhesion molecule N-terminal domain TonB_N PF16031.5 OAF99455.1 - 0.018 15.6 16.6 0.021 15.3 16.6 1.1 1 0 0 1 1 1 0 TonB polyproline region Neisseria_TspB PF05616.13 OAF99455.1 - 6.1 5.2 9.1 6.7 5.1 9.1 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Copper-bind PF00127.20 OAF99456.1 - 0.00036 20.9 0.1 0.00082 19.8 0.1 1.5 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 OAF99456.1 - 0.021 14.8 0.2 0.24 11.5 0.2 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain Cupredoxin_1 PF13473.6 OAF99456.1 - 0.042 14.0 0.0 0.074 13.2 0.0 1.4 2 0 0 2 2 2 0 Cupredoxin-like domain DX PF01666.17 OAF99456.1 - 0.14 12.6 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 DX module Cerato-platanin PF07249.12 OAF99457.1 - 3.9e-55 185.1 4.7 4.5e-55 184.9 4.7 1.0 1 0 0 1 1 1 1 Cerato-platanin AAT PF03417.16 OAF99458.1 - 3.2e-22 79.3 0.0 3.7e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DHO_dh PF01180.21 OAF99458.1 - 0.087 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Polysacc_deac_1 PF01522.21 OAF99459.1 - 6.2e-22 77.8 0.0 8.9e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAF99459.1 - 6.1e-15 55.4 0.3 1.1e-14 54.6 0.3 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAF99459.1 - 1.5e-06 27.6 0.1 2.1e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2194 PF09960.9 OAF99459.1 - 0.0023 16.4 0.0 0.0031 16.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) DUF4023 PF13215.6 OAF99459.1 - 0.019 15.0 0.2 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) DUF3674 PF12426.8 OAF99459.1 - 0.04 13.9 1.1 0.11 12.6 1.1 1.7 1 0 0 1 1 1 0 RNA dependent RNA polymerase Fungal_trans PF04082.18 OAF99462.1 - 1.3e-19 70.3 0.9 1.8e-19 69.8 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF99462.1 - 3.3e-10 39.9 6.4 6.7e-10 38.9 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 OAF99464.1 - 3.8e-29 100.3 0.1 3e-15 55.8 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAF99464.1 - 0.00018 21.6 0.0 0.12 12.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OAF99464.1 - 0.00056 19.5 0.0 1.4 8.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAF99464.1 - 0.087 12.9 0.0 19 5.4 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 FAD_binding_1 PF00667.20 OAF99465.1 - 1.7e-33 116.1 0.0 2.9e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAF99465.1 - 2e-29 102.6 0.0 4e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAF99465.1 - 3e-14 53.6 0.0 7.7e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAF99465.1 - 0.032 14.5 0.1 2.6 8.3 0.0 2.5 1 1 1 2 2 2 0 Flavodoxin domain POPLD PF08170.12 OAF99465.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 POPLD (NUC188) domain F-box-like PF12937.7 OAF99466.1 - 1.1e-05 25.2 0.1 7.2e-05 22.6 0.0 2.5 3 0 0 3 3 3 1 F-box-like PRANC PF09372.10 OAF99466.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 PRANC domain Glyco_hydro_17 PF00332.18 OAF99468.1 - 0.031 13.9 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 ILVD_EDD PF00920.21 OAF99469.1 - 3.6e-208 692.4 0.4 4.2e-208 692.2 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 OAF99469.1 - 0.023 14.9 0.0 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain ICMT PF04140.14 OAF99470.1 - 1.4e-26 92.7 0.5 3.4e-26 91.5 0.5 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAF99470.1 - 6.3e-11 42.6 2.8 6.3e-11 42.6 2.8 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAF99470.1 - 1.6e-08 34.4 1.8 2.1e-08 34.0 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 OAF99470.1 - 3e-07 30.2 1.5 6.1e-07 29.2 1.5 1.5 1 0 0 1 1 1 1 NnrU protein Mac PF12464.8 OAF99471.1 - 9.5e-13 48.2 0.5 1.6e-12 47.4 0.5 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 OAF99471.1 - 5.7e-12 44.9 8.8 2.1e-09 36.7 6.4 2.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAF99471.1 - 3.9e-10 39.3 8.9 9.8e-10 38.0 5.0 2.5 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase K-cyclin_vir_C PF09080.10 OAF99472.1 - 0.02 15.3 0.0 0.066 13.6 0.0 1.9 1 0 0 1 1 1 0 K cyclin, C terminal zf-C3HC4 PF00097.25 OAF99473.1 - 2.4e-07 30.5 6.6 2.4e-07 30.5 6.6 4.7 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAF99473.1 - 2.6e-06 27.6 6.9 2.6e-06 27.6 6.9 4.4 4 1 0 4 4 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OAF99473.1 - 3.7e-06 26.9 5.6 3.7e-06 26.9 5.6 3.8 5 0 0 5 5 3 1 RING-type zinc-finger zf-RING_6 PF14835.6 OAF99473.1 - 5.7e-06 26.1 0.5 5.7e-06 26.1 0.5 2.4 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 OAF99473.1 - 7.8e-06 25.6 7.4 7.8e-06 25.6 7.4 3.7 5 1 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 OAF99473.1 - 1.1e-05 25.2 4.9 1.1e-05 25.2 4.9 3.8 4 0 0 4 4 3 2 Zinc finger, ZZ type zf-C3HC4_3 PF13920.6 OAF99473.1 - 9.2e-05 22.2 3.2 9.2e-05 22.2 3.2 5.0 4 2 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAF99473.1 - 0.00024 21.2 8.4 0.00024 21.2 8.4 3.5 5 0 0 5 5 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAF99473.1 - 0.00058 19.8 5.6 0.00058 19.8 5.6 5.1 5 1 0 5 5 5 1 zinc-RING finger domain CpXC PF14353.6 OAF99473.1 - 0.0069 16.4 0.1 0.03 14.4 0.1 2.1 1 0 0 1 1 1 1 CpXC protein SH3_1 PF00018.28 OAF99473.1 - 0.081 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 SH3 domain C1_2 PF03107.16 OAF99473.1 - 4.6 7.6 47.3 0.2 12.0 6.7 4.9 4 1 0 4 4 4 0 C1 domain Band_7 PF01145.25 OAF99473.1 - 6.4 6.7 7.9 3.7 7.5 5.3 1.9 2 0 0 2 2 2 0 SPFH domain / Band 7 family PhoLip_ATPase_C PF16212.5 OAF99474.1 - 6.2e-83 278.4 20.1 6.2e-83 278.4 20.1 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAF99474.1 - 3.1e-28 97.3 5.6 8.4e-28 95.9 5.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAF99474.1 - 1e-11 44.7 0.0 4.4e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAF99474.1 - 8.3e-11 42.6 2.7 7.8e-07 29.6 0.9 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAF99474.1 - 1e-05 25.1 0.0 2.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAF99474.1 - 0.001 18.9 0.6 0.0032 17.2 0.5 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 OAF99476.1 - 1.6e-24 86.5 52.4 1e-20 74.0 33.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF99477.1 - 1.8e-95 320.5 22.8 2.1e-95 320.2 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99477.1 - 1.3e-22 80.2 25.8 1.2e-21 77.1 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 OAF99477.1 - 0.00057 18.9 0.7 0.00057 18.9 0.7 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Phage_holin_3_2 PF04550.12 OAF99477.1 - 0.11 13.0 0.4 0.11 13.0 0.4 2.5 3 0 0 3 3 3 0 Phage holin family 2 F-box PF00646.33 OAF99478.1 - 0.001 18.9 0.1 0.001 18.9 0.1 2.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OAF99478.1 - 0.016 15.1 1.5 0.024 14.5 0.1 2.1 2 0 0 2 2 2 0 F-box-like DUF2009 PF09418.10 OAF99478.1 - 0.059 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF924 PF06041.11 OAF99479.1 - 7e-49 166.4 0.1 7.8e-49 166.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Pkinase PF00069.25 OAF99480.1 - 9.7e-36 123.5 0.0 1.5e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF99480.1 - 1.5e-16 60.5 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Hce2 PF14856.6 OAF99481.1 - 4.4e-17 62.2 0.4 5.6e-17 61.9 0.4 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF3330 PF11809.8 OAF99481.1 - 0.028 14.5 0.1 0.054 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) DHHA1 PF02272.19 OAF99481.1 - 0.21 12.0 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 DHHA1 domain cobW PF02492.19 OAF99482.1 - 2.3e-50 170.7 5.2 2.2e-47 160.9 5.2 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAF99482.1 - 3.3e-19 68.6 0.0 2e-14 53.3 0.0 2.7 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 OAF99482.1 - 0.0062 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAF99482.1 - 0.0084 16.3 0.0 0.071 13.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAF99482.1 - 0.013 15.9 1.3 0.023 15.1 0.2 2.1 2 1 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 OAF99482.1 - 0.014 15.0 1.0 0.43 10.1 0.3 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Viral_helicase1 PF01443.18 OAF99482.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 OAF99482.1 - 0.026 14.4 0.4 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 OAF99482.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 OAF99482.1 - 0.049 13.6 0.0 0.14 12.0 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OAF99482.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain polyprenyl_synt PF00348.17 OAF99483.1 - 1.5e-92 309.3 0.0 2e-92 308.9 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 OAF99483.1 - 0.02 15.1 0.5 0.07 13.3 0.2 1.9 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain ANAPC8 PF04049.13 OAF99484.1 - 4.6e-48 162.8 0.0 9.3e-48 161.8 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 OAF99484.1 - 2.4e-25 87.2 0.4 0.0003 20.5 0.1 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAF99484.1 - 1.6e-18 65.3 3.9 0.0043 17.2 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAF99484.1 - 8.3e-11 41.2 16.3 0.5 10.6 0.3 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAF99484.1 - 3.3e-10 40.4 4.2 0.0071 17.0 0.0 6.2 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAF99484.1 - 7e-09 35.2 0.3 2.2e-05 24.0 0.0 5.1 4 2 2 6 6 6 1 TPR repeat TPR_14 PF13428.6 OAF99484.1 - 8.7e-08 32.4 19.8 0.17 12.8 0.0 9.0 7 1 3 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAF99484.1 - 1.4e-05 25.2 7.9 1.7 8.9 0.1 6.1 5 2 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OAF99484.1 - 1.5e-05 25.2 11.2 1.4 9.2 1.0 6.4 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAF99484.1 - 1.6e-05 25.0 3.5 4.2 7.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAF99484.1 - 0.00054 19.8 7.6 0.12 12.4 0.0 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAF99484.1 - 0.00059 20.0 0.5 7.6 7.2 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAF99484.1 - 0.00059 20.3 0.6 1.2 9.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAF99484.1 - 0.00094 19.7 13.7 6.7 7.6 0.5 7.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAF99484.1 - 0.018 14.3 4.0 0.091 12.0 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat SRP68 PF16969.5 OAF99484.1 - 0.099 11.6 0.1 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 RNA-binding signal recognition particle 68 Arm-DNA-bind_3 PF13356.6 OAF99484.1 - 0.13 12.7 0.8 0.42 11.0 0.1 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain Pro_racemase PF05544.11 OAF99486.1 - 2.4e-63 214.1 0.0 3.7e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 OAF99486.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Peroxidase_2 PF01328.17 OAF99487.1 - 1.4e-41 143.1 0.0 2e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Sugar_tr PF00083.24 OAF99488.1 - 1.3e-99 334.2 31.9 1.5e-99 334.0 31.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99488.1 - 1.8e-29 102.8 27.7 1.8e-29 102.8 27.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily RPE65 PF03055.15 OAF99489.1 - 3.1e-75 254.2 0.0 3.5e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein EthD PF07110.11 OAF99490.1 - 1.4e-09 39.0 0.3 2e-09 38.5 0.3 1.2 1 0 0 1 1 1 1 EthD domain Peptidase_M18 PF02127.15 OAF99491.1 - 1.8e-130 435.6 0.0 2.2e-130 435.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) IPP-2 PF04979.14 OAF99492.1 - 2.3e-23 83.4 11.3 4.1e-23 82.6 11.3 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Amastin PF07344.11 OAF99493.1 - 0.037 13.9 0.0 0.039 13.8 0.0 1.0 1 0 0 1 1 1 0 Amastin surface glycoprotein IF4E PF01652.18 OAF99494.1 - 1.2e-53 181.1 0.6 1.8e-53 180.6 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Serglycin PF04360.12 OAF99495.1 - 0.16 11.9 1.2 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Serglycin Peptidase_C48 PF02902.19 OAF99496.1 - 2.6e-28 99.3 0.0 7.8e-28 97.8 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PQ-loop PF04193.14 OAF99497.1 - 3.1e-21 74.9 1.1 1.1e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 OAF99497.1 - 0.0039 18.0 5.0 0.0059 17.4 5.0 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor GGACT PF06094.12 OAF99498.1 - 1.4e-17 64.4 0.0 2.8e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GFA PF04828.14 OAF99500.1 - 8e-18 64.6 0.7 1.2e-17 64.0 0.7 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 OAF99500.1 - 1.1 9.5 8.0 1.8 8.8 0.1 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Glycophorin_A PF01102.18 OAF99503.1 - 0.04 14.2 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A AMP-binding PF00501.28 OAF99504.1 - 2.9e-43 148.0 0.0 3.9e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAF99504.1 - 0.016 16.1 0.0 0.04 14.9 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain YiaAB PF05360.14 OAF99505.1 - 2.9 8.2 8.5 1.9 8.8 0.1 3.4 3 0 0 3 3 3 0 yiaA/B two helix domain DUF2157 PF09925.9 OAF99505.1 - 3.6 7.4 12.3 1.7 8.4 6.4 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) CAF1A PF12253.8 OAF99506.1 - 1.6e-21 76.3 6.1 1.6e-21 76.3 6.1 3.2 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A SprA-related PF12118.8 OAF99506.1 - 0.6 9.2 25.4 0.93 8.6 25.4 1.2 1 0 0 1 1 1 0 SprA-related family DUF966 PF06136.13 OAF99506.1 - 0.82 9.3 22.9 1.3 8.7 22.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hamartin PF04388.12 OAF99506.1 - 2.1 6.9 23.8 3 6.4 23.8 1.1 1 0 0 1 1 1 0 Hamartin protein RR_TM4-6 PF06459.12 OAF99506.1 - 4.4 7.0 33.7 0.098 12.5 26.5 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 OAF99506.1 - 6.7 5.3 20.8 11 4.7 20.8 1.2 1 0 0 1 1 1 0 Raftlin TP6A_N PF04406.14 OAF99507.1 - 1.3e-22 79.5 0.0 3e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase F-box-like PF12937.7 OAF99509.1 - 2.4e-06 27.3 0.2 5e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAF99509.1 - 2.6e-05 24.0 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 F-box domain BCDHK_Adom3 PF10436.9 OAF99511.1 - 4.8e-43 146.8 0.1 8.8e-43 145.9 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAF99511.1 - 2e-06 28.3 0.0 1e-05 26.0 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAF99511.1 - 0.0058 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.8 OAF99512.1 - 6.7e-79 264.6 0.1 6.2e-78 261.4 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OAF99512.1 - 2.3e-66 223.4 1.0 8.4e-66 221.6 0.7 2.2 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 OAF99512.1 - 8e-48 163.2 0.8 1.5e-47 162.3 0.8 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAF99512.1 - 4.2e-20 72.6 0.1 1e-19 71.3 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 OAF99512.1 - 3.9e-07 30.2 0.0 3.3e-06 27.2 0.0 2.7 3 0 0 3 3 3 1 MATH domain Rad60-SLD PF11976.8 OAF99512.1 - 0.012 15.5 0.8 4 7.3 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 OAF99512.1 - 0.082 13.6 0.0 15 6.3 0.0 2.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DUF4974 PF16344.5 OAF99512.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) EMP24_GP25L PF01105.24 OAF99513.1 - 7.1e-48 163.0 1.5 8.1e-48 162.8 1.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DIX PF00778.17 OAF99513.1 - 0.029 14.2 0.3 0.27 11.1 0.1 2.3 2 0 0 2 2 2 0 DIX domain F-box PF00646.33 OAF99514.1 - 7.9e-05 22.4 2.0 7.9e-05 22.4 2.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAF99514.1 - 0.0027 17.6 1.0 0.0077 16.1 1.0 1.7 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 OAF99516.1 - 7.9e-87 292.0 22.7 9.9e-87 291.7 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99516.1 - 4.3e-12 45.6 45.9 1.4e-07 30.8 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 OAF99517.1 - 1.1e-24 86.4 0.3 1.5e-24 85.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) CHORD PF04968.12 OAF99518.1 - 0.019 15.7 2.7 0.044 14.5 2.7 1.6 1 0 0 1 1 1 0 CHORD Herpes_DNAp_acc PF04929.12 OAF99519.1 - 0.32 9.9 1.9 0.34 9.8 1.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor AT_hook PF02178.19 OAF99519.1 - 1.2 9.2 10.4 0.63 10.1 1.2 2.8 3 0 0 3 3 3 0 AT hook motif RR_TM4-6 PF06459.12 OAF99520.1 - 0.0048 16.8 5.6 0.0048 16.8 5.6 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 OAF99520.1 - 0.0069 15.6 6.8 0.0073 15.5 6.8 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1840 PF08895.11 OAF99520.1 - 0.031 14.6 2.8 0.031 14.6 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Zip PF02535.22 OAF99520.1 - 0.032 13.5 1.1 0.037 13.3 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 OAF99520.1 - 0.038 11.9 1.4 0.034 12.1 1.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FHIPEP PF00771.20 OAF99520.1 - 0.053 12.0 0.1 0.058 11.9 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family Sigma70_ner PF04546.13 OAF99520.1 - 0.057 13.3 12.5 0.053 13.4 12.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF913 PF06025.12 OAF99520.1 - 0.065 12.2 1.4 0.064 12.2 1.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3328 PF11807.8 OAF99520.1 - 0.084 12.6 0.0 0.096 12.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) RAB3GAP2_C PF14656.6 OAF99520.1 - 0.12 10.6 2.0 0.1 10.8 2.0 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus MAP17 PF15807.5 OAF99520.1 - 0.13 12.5 4.2 0.13 12.5 4.2 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RNA_pol_Rpc4 PF05132.14 OAF99520.1 - 0.13 12.7 4.0 0.13 12.6 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 OAF99520.1 - 0.25 11.5 6.1 0.3 11.3 6.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.15 OAF99520.1 - 0.48 9.3 0.3 0.47 9.3 0.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3306 PF11748.8 OAF99520.1 - 0.82 10.5 8.7 0.91 10.4 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF740 PF05340.12 OAF99520.1 - 1.8 7.2 10.9 1.9 7.1 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Saw1 PF11561.8 OAF99520.1 - 2.8 7.4 5.1 3 7.3 5.1 1.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Prothymosin PF03247.14 OAF99520.1 - 2.9 8.4 37.6 3.7 8.1 37.6 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Presenilin PF01080.17 OAF99520.1 - 6.5 5.4 7.8 7.6 5.2 7.8 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 OAF99520.1 - 7.1 4.7 24.2 8 4.5 24.2 1.1 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 OAF99520.1 - 8.4 6.3 17.1 9.6 6.1 17.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CENP-T_N PF16171.5 OAF99520.1 - 9.2 5.1 9.2 8.7 5.1 9.2 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus FAT PF02259.23 OAF99521.1 - 1.5e-73 248.0 8.0 3.5e-73 246.8 8.0 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OAF99521.1 - 6.4e-35 121.2 0.1 1.5e-34 120.0 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OAF99521.1 - 0.00034 20.4 0.2 0.0011 18.7 0.2 2.0 1 0 0 1 1 1 1 FATC domain FANCI_S2 PF14676.6 OAF99521.1 - 0.0057 17.0 0.1 0.82 10.0 0.0 4.6 3 0 0 3 3 3 1 FANCI solenoid 2 Phasin_2 PF09361.10 OAF99521.1 - 0.061 13.6 1.6 0.71 10.2 0.5 3.2 2 0 0 2 2 2 0 Phasin protein MRFAP1 PF15155.6 OAF99521.1 - 0.064 13.8 0.4 35 4.9 0.0 3.8 4 0 0 4 4 4 0 MORF4 family-associated protein1 Hypoth_Ymh PF09509.10 OAF99521.1 - 1 9.3 4.2 36 4.3 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (Hypoth_ymh) Tau95_N PF17682.1 OAF99522.1 - 1.3e-31 109.5 0.0 2.6e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 OAF99522.1 - 1.3e-28 100.5 0.1 3.1e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain B56 PF01603.20 OAF99523.1 - 6.3e-191 634.8 5.3 7.5e-191 634.6 5.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 OAF99523.1 - 0.00052 20.0 1.5 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SOG2 PF10428.9 OAF99523.1 - 6.6 5.8 9.2 25 3.9 0.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Sporozoite_P67 PF05642.11 OAF99523.1 - 9.9 4.1 12.0 16 3.4 12.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ELO PF01151.18 OAF99524.1 - 1e-59 202.1 23.7 1.2e-59 201.9 23.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Kelch_5 PF13854.6 OAF99524.1 - 0.065 13.2 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Kelch motif COX5A PF02284.16 OAF99525.1 - 4.9e-42 142.1 0.3 6.8e-42 141.7 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF725 PF05267.12 OAF99525.1 - 0.038 14.0 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) GATase_5 PF13507.6 OAF99526.1 - 8.1e-102 339.8 0.0 1.2e-101 339.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OAF99526.1 - 2.3e-38 131.8 0.0 1.8e-26 93.1 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OAF99526.1 - 5.3e-34 116.7 0.0 1e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 OAF99526.1 - 5.5e-21 74.9 1.4 8.9e-21 74.2 0.3 2.1 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain Glyco_transf_15 PF01793.16 OAF99527.1 - 8.6e-112 373.6 7.3 1.1e-111 373.3 7.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 OAF99528.1 - 4e-42 144.9 1.1 6.9e-42 144.1 1.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAF99528.1 - 7.2e-25 88.1 0.6 7.2e-25 88.1 0.6 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 OAF99528.1 - 0.0014 17.1 2.9 0.38 9.1 0.0 3.3 3 0 0 3 3 3 3 gamma-Tubulin ring complex non-core subunit mod21 Fungal_trans_2 PF11951.8 OAF99529.1 - 4.7e-09 35.5 1.2 2.8e-08 33.0 1.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF99529.1 - 1.6e-06 28.1 8.4 2.5e-06 27.5 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3450 PF11932.8 OAF99530.1 - 0.003 16.9 2.4 0.003 16.9 2.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 OAF99530.1 - 1.7 8.7 3.8 14 5.7 0.3 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5446 PF17522.2 OAF99530.1 - 2.6 8.3 6.9 0.46 10.7 0.9 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5446) Macoilin PF09726.9 OAF99530.1 - 7.7 4.9 24.9 45 2.4 24.8 2.1 1 1 0 1 1 1 0 Macoilin family 4HBT_2 PF13279.6 OAF99531.1 - 4.9e-27 94.9 0.1 7.1e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAF99531.1 - 0.00035 20.9 0.0 0.00058 20.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 OAF99531.1 - 0.031 13.6 0.1 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Acyl-ACP thioesterase Complex1_LYR PF05347.15 OAF99532.1 - 2.7e-06 27.3 0.4 4.4e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAF99532.1 - 3.5e-06 27.7 2.9 5.3e-06 27.1 2.9 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_25 PF13649.6 OAF99533.1 - 4.6e-14 52.9 0.0 8.3e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAF99533.1 - 8e-13 48.9 0.0 1.6e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAF99533.1 - 5.8e-10 39.3 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAF99533.1 - 2.3e-08 34.0 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAF99533.1 - 3.6e-08 34.0 0.0 7.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAF99533.1 - 9.6e-06 25.1 0.0 2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 OAF99533.1 - 0.00021 21.2 0.0 0.00034 20.5 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Exo_endo_phos PF03372.23 OAF99534.1 - 8.5e-22 77.8 0.1 9.3e-21 74.4 0.1 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 OAF99534.1 - 6.3e-07 29.1 12.1 2e-05 24.2 3.5 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAF99534.1 - 0.0011 19.4 10.7 0.0084 16.5 1.5 2.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) TFIIA PF03153.13 OAF99534.1 - 4.5 7.2 11.7 7 6.5 11.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRAL_TRIO PF00650.20 OAF99535.1 - 3.4e-36 124.4 0.0 6.8e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAF99535.1 - 5.1e-07 29.8 0.1 1.1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAF99535.1 - 0.029 14.5 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Glyco_hydro_17 PF00332.18 OAF99537.1 - 7.3e-06 25.8 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 F-box-like PF12937.7 OAF99539.1 - 2.4 8.1 7.9 0.11 12.4 0.9 2.5 3 0 0 3 3 3 0 F-box-like SMC_N PF02463.19 OAF99540.1 - 2e-24 86.2 11.0 2.5e-13 50.0 0.9 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAF99540.1 - 2.5e-16 60.8 13.9 2.5e-16 60.8 13.9 5.4 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 OAF99540.1 - 4.6e-08 33.2 12.9 4.6e-08 33.2 12.9 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAF99540.1 - 1.1e-07 32.0 3.2 9.5e-06 25.6 0.5 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAF99540.1 - 0.0013 18.5 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 OAF99540.1 - 0.004 17.4 0.0 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit KxDL PF10241.9 OAF99540.1 - 0.015 15.6 3.2 0.015 15.6 3.2 6.7 4 1 3 7 7 7 0 Uncharacterized conserved protein SMC_hinge PF06470.13 OAF99540.1 - 0.021 15.2 0.7 0.22 11.8 0.0 2.9 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Fur_reg_FbpB PF13040.6 OAF99540.1 - 0.029 13.9 2.0 0.078 12.5 0.4 2.5 2 0 0 2 2 2 0 Fur-regulated basic protein B DUF5595 PF18077.1 OAF99540.1 - 0.3 11.2 6.7 0.28 11.3 1.9 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) AAA_22 PF13401.6 OAF99540.1 - 3.6 7.8 6.1 8 6.7 0.0 3.8 3 1 0 3 3 3 0 AAA domain ANAPC1 PF12859.7 OAF99542.1 - 5.1e-35 120.9 0.7 5.1e-35 120.9 0.7 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 Pyrid_ox_like PF16242.5 OAF99543.1 - 7.1e-21 74.3 0.0 1.1e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAF99543.1 - 2.7e-08 33.9 0.0 4.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UCH PF00443.29 OAF99544.1 - 3e-49 167.8 0.1 4.2e-49 167.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAF99544.1 - 2.3e-26 93.2 3.5 8.1e-25 88.1 3.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAF99544.1 - 1.4e-05 25.4 0.0 7.2e-05 23.0 0.0 2.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein E6 PF00518.17 OAF99544.1 - 0.0079 16.6 2.3 3.3 8.2 0.1 2.6 2 0 0 2 2 2 2 Early Protein (E6) Transferase PF02458.15 OAF99545.1 - 3.5e-29 101.8 0.0 4e-15 55.4 0.0 3.0 2 1 0 2 2 2 2 Transferase family TBCC PF07986.12 OAF99546.1 - 4.3e-31 107.2 0.0 5.8e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 OAF99546.1 - 1.3e-06 28.9 0.0 2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain NAD_binding_10 PF13460.6 OAF99547.1 - 5.1e-05 23.2 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding UPF0154 PF03672.13 OAF99547.1 - 0.58 10.2 2.0 8.5 6.5 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Tim17 PF02466.19 OAF99548.1 - 2.5e-05 24.6 6.3 6.2e-05 23.3 6.2 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Colicin_V PF02674.16 OAF99548.1 - 0.19 11.7 2.1 1.2 9.1 0.5 2.2 1 1 1 2 2 2 0 Colicin V production protein RPT PF13446.6 OAF99549.1 - 5.3e-42 141.5 0.2 1.4e-16 60.1 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 OAF99549.1 - 5.5e-35 121.1 0.0 1.5e-34 119.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAF99549.1 - 0.01 15.4 0.0 0.044 13.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase E7 PF00527.18 OAF99549.1 - 0.07 13.3 0.7 0.34 11.1 0.1 2.4 2 0 0 2 2 2 0 E7 protein, Early protein Prefoldin_2 PF01920.20 OAF99549.1 - 0.25 11.3 5.8 5.9 6.9 0.0 2.9 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.6 OAF99549.1 - 0.3 11.6 10.5 2.5 8.6 0.1 3.8 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 OAF99549.1 - 5.1 7.4 8.0 21 5.4 0.6 4.2 5 0 0 5 5 5 0 Spc24 subunit of Ndc80 Ribosomal_S21e PF01249.18 OAF99550.1 - 1.6e-38 130.7 0.0 1.7e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e PH PF00169.29 OAF99551.1 - 1.5e-05 25.5 0.0 3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 OAF99551.1 - 0.039 11.9 0.9 0.055 11.4 0.9 1.1 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 OAF99551.1 - 0.12 12.7 1.2 0.33 11.3 1.2 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sugar_tr PF00083.24 OAF99552.1 - 0.00024 20.1 3.8 0.00025 20.0 3.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99552.1 - 0.01 14.8 5.2 0.011 14.7 5.2 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.16 OAF99553.1 - 1.4e-09 37.3 4.7 1.6e-09 37.2 4.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAF99553.1 - 0.0085 14.6 1.9 0.009 14.5 1.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CP2 PF04516.15 OAF99554.1 - 1.3e-82 276.6 0.0 2.3e-82 275.8 0.0 1.4 1 0 0 1 1 1 1 CP2 transcription factor AKNA PF12443.8 OAF99554.1 - 0.073 13.7 0.3 0.21 12.2 0.3 1.8 1 0 0 1 1 1 0 AT-hook-containing transcription factor Tektin PF03148.14 OAF99554.1 - 0.1 11.3 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Tektin family CENP-K PF11802.8 OAF99556.1 - 0.00085 19.0 5.8 0.37 10.3 2.0 2.6 2 2 0 2 2 2 2 Centromere-associated protein K PKcGMP_CC PF16808.5 OAF99556.1 - 0.037 13.9 1.8 0.052 13.4 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Laminin_II PF06009.12 OAF99556.1 - 3.2 7.8 11.5 4.5 7.3 1.1 2.7 2 1 0 2 2 2 0 Laminin Domain II TFIIA PF03153.13 OAF99556.1 - 3.5 7.5 12.4 5.1 7.0 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Syntaxin-6_N PF09177.11 OAF99556.1 - 5 7.8 7.3 1.8 9.1 2.2 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal KH_1 PF00013.29 OAF99557.1 - 5.5e-43 144.6 6.1 2.7e-18 65.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAF99557.1 - 5e-12 45.5 2.2 0.0044 16.8 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAF99557.1 - 9.1e-06 25.7 4.4 0.25 11.5 0.2 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 OAF99557.1 - 2.4e-05 24.2 0.0 0.0068 16.4 0.0 2.6 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_4 PF13083.6 OAF99557.1 - 5e-05 23.1 0.9 1.2 9.1 0.0 3.3 3 0 0 3 3 3 2 KH domain BTB PF00651.31 OAF99558.1 - 1.2e-09 38.3 0.0 2.8e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain Abhydrolase_6 PF12697.7 OAF99559.1 - 1.4e-12 48.7 0.0 1.8e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Adeno_PIX PF03955.14 OAF99559.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Aldedh PF00171.22 OAF99560.1 - 4.7e-114 381.4 3.9 5.7e-114 381.2 3.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.18 OAF99561.1 - 3.9e-19 69.1 3.8 5.6e-19 68.6 3.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HA2 PF04408.23 OAF99563.1 - 1.2e-21 77.0 0.0 3.2e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAF99563.1 - 6e-12 45.9 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OAF99563.1 - 2.7e-11 43.7 0.0 5.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OAF99563.1 - 1.1e-07 31.8 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAF99563.1 - 3.2e-06 27.5 0.0 8.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAF99563.1 - 0.00014 22.2 0.0 0.00028 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAF99563.1 - 0.00033 20.4 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAF99563.1 - 0.0038 16.3 0.0 0.0074 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 OAF99563.1 - 0.0065 16.2 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAF99563.1 - 0.011 16.3 0.0 0.033 14.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 OAF99563.1 - 0.018 15.0 0.1 0.055 13.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 OAF99563.1 - 0.033 13.6 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OAF99563.1 - 0.058 13.8 0.1 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Helicase_RecD PF05127.14 OAF99563.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Helicase Rhabdo_M1 PF03342.13 OAF99563.1 - 4 6.7 6.9 2.6 7.4 4.3 1.9 2 0 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Glyco_hyd_65N_2 PF14498.6 OAF99564.1 - 0.014 15.3 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TPR_4 PF07721.14 OAF99564.1 - 0.22 12.2 2.5 0.58 10.9 2.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Melibiase_2 PF16499.5 OAF99565.1 - 2.5e-49 168.0 6.9 3e-48 164.4 6.9 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OAF99565.1 - 4.5e-10 39.5 1.1 1.2e-08 34.9 0.5 2.5 1 1 1 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAF99565.1 - 8.7e-05 21.6 0.1 0.00021 20.4 0.0 1.5 2 0 0 2 2 2 1 Melibiase Peptidase_C14 PF00656.22 OAF99567.1 - 4.7e-07 30.0 0.0 9.2e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Caspase domain DUF3952 PF13130.6 OAF99567.1 - 0.18 12.0 0.1 0.96 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) Histone_HNS PF00816.21 OAF99570.1 - 0.045 14.6 0.5 0.51 11.2 0.6 2.2 2 0 0 2 2 2 0 H-NS histone family DNA_ligase_A_M PF01068.21 OAF99571.1 - 4.5e-50 170.1 0.1 2.9e-47 160.9 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAF99571.1 - 1.4e-36 126.4 0.0 2.6e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAF99571.1 - 7.4e-19 68.2 0.4 3.8e-18 65.9 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 OAF99571.1 - 0.04 13.7 0.1 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain SUI1 PF01253.22 OAF99572.1 - 2.6e-28 98.4 4.3 3.9e-28 97.8 3.9 1.5 2 0 0 2 2 2 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 OAF99572.1 - 0.053 13.8 0.2 0.092 13.0 0.2 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF3431 PF11913.8 OAF99574.1 - 1.3e-09 38.2 0.1 2.8e-08 33.8 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) DUF1275 PF06912.11 OAF99574.1 - 0.0043 17.0 8.1 0.0043 17.0 8.1 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF1275) COesterase PF00135.28 OAF99575.1 - 2.5e-70 237.8 0.0 3.2e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAF99575.1 - 1.9e-08 34.4 0.2 2.1e-07 31.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold ARL17 PF15840.5 OAF99575.1 - 0.35 11.3 1.9 0.75 10.2 0.2 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor-like protein 17 YtxH PF12732.7 OAF99576.1 - 0.093 13.3 10.7 0.092 13.3 6.9 2.1 1 1 1 2 2 2 0 YtxH-like protein ISG65-75 PF11727.8 OAF99576.1 - 0.11 11.7 9.4 0.14 11.3 9.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein CsbD PF05532.12 OAF99576.1 - 0.16 11.9 23.9 0.65 9.9 20.1 3.1 2 1 1 3 3 3 0 CsbD-like Borrelia_P83 PF05262.11 OAF99576.1 - 0.29 9.6 7.6 0.31 9.5 7.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF883 PF05957.13 OAF99576.1 - 0.52 11.0 5.9 0.33 11.6 2.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 OAF99576.1 - 5.8 7.0 13.9 8.3 6.5 10.0 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) AAA PF00004.29 OAF99577.1 - 2.8e-45 154.0 0.5 6.6e-45 152.8 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAF99577.1 - 6.2e-10 38.9 0.1 4e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAF99577.1 - 9.5e-09 35.4 0.1 3.1e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAF99577.1 - 6.3e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAF99577.1 - 1.2e-07 32.3 0.1 3.5e-05 24.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 OAF99577.1 - 6.7e-06 25.4 0.2 1.4e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAF99577.1 - 4.9e-05 23.6 1.4 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 OAF99577.1 - 0.00028 20.6 0.0 0.00066 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OAF99577.1 - 0.00032 20.5 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAF99577.1 - 0.00059 20.4 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OAF99577.1 - 0.00078 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 OAF99577.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 OAF99577.1 - 0.0016 18.5 0.0 0.021 14.9 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 OAF99577.1 - 0.0018 17.6 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 OAF99577.1 - 0.0019 17.8 0.1 0.0096 15.4 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 OAF99577.1 - 0.0019 18.2 0.1 0.0069 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAF99577.1 - 0.0032 17.4 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 OAF99577.1 - 0.0053 16.5 0.1 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAF99577.1 - 0.0062 16.7 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OAF99577.1 - 0.0066 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAF99577.1 - 0.0086 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OAF99577.1 - 0.0089 16.0 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TniB PF05621.11 OAF99577.1 - 0.009 15.4 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 OAF99577.1 - 0.016 14.9 0.1 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAF99577.1 - 0.018 14.7 0.2 0.046 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain Viral_Hsp90 PF03225.14 OAF99577.1 - 0.037 12.6 0.0 0.059 11.9 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue ATPase_2 PF01637.18 OAF99577.1 - 0.038 13.9 0.8 0.21 11.5 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 OAF99577.1 - 0.038 13.3 1.6 0.56 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 OAF99577.1 - 0.043 13.4 0.8 0.26 10.9 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 OAF99577.1 - 0.049 13.4 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 OAF99577.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 OAF99577.1 - 0.076 12.7 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 OAF99577.1 - 0.092 11.6 0.3 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.6 OAF99577.1 - 0.11 13.0 0.8 5.4 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAF99577.1 - 0.14 12.5 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAF99577.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 OAF99577.1 - 0.21 10.6 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ARID PF01388.21 OAF99579.1 - 1.7e-17 63.9 0.1 1.3e-16 61.0 0.0 2.6 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 OAF99579.1 - 0.027 13.8 1.2 0.14 11.5 0.1 2.4 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Collagen PF01391.18 OAF99579.1 - 0.074 12.8 2.5 0.15 11.8 2.5 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) RPAP1_C PF08620.10 OAF99580.1 - 1.7e-26 92.1 0.0 3.2e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 OAF99580.1 - 3.2e-18 65.2 6.7 6.9e-18 64.2 6.7 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal CEP170_C PF15308.6 OAF99581.1 - 0.2 10.2 0.0 0.22 10.1 0.0 1.0 1 0 0 1 1 1 0 CEP170 C-terminus Img2 PF05046.14 OAF99582.1 - 9.9e-27 93.1 0.1 1.3e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 OAF99583.1 - 2.6e-33 115.3 2.4 1.5e-32 112.8 2.0 2.3 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OAF99583.1 - 5.5e-14 52.6 0.1 1.9e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain XPB_DRD PF18458.1 OAF99584.1 - 0.12 12.3 1.7 12 5.8 0.0 2.8 3 0 0 3 3 3 0 Xeroderma pigmentosum group B helicase damage recognition domain CRM1_repeat_3 PF18787.1 OAF99584.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 DUF2985 PF11204.8 OAF99586.1 - 7.7e-22 77.2 3.7 1.6e-21 76.2 3.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) zf-H2C2 PF09337.10 OAF99587.1 - 1.4e-15 57.2 0.7 2.7e-15 56.3 0.7 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 OAF99587.1 - 4e-12 46.0 0.2 6.7e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 OAF99587.1 - 0.00032 20.9 0.0 0.00055 20.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAF99587.1 - 0.003 17.7 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cullin PF00888.22 OAF99588.1 - 3.6e-15 55.6 0.0 6.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 OAF99588.1 - 5e-13 49.4 0.2 1.5e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 FKBP_C PF00254.28 OAF99589.1 - 1.9e-26 92.2 0.0 2.3e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Prefoldin PF02996.17 OAF99590.1 - 1.8e-35 121.4 0.1 3.2e-35 120.6 0.0 1.4 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 OAF99590.1 - 6.9e-05 22.7 1.1 0.00076 19.4 0.0 2.4 2 1 0 2 2 2 1 Prefoldin subunit THOC7 PF05615.13 OAF99590.1 - 0.003 17.8 0.8 0.66 10.3 0.0 2.2 2 0 0 2 2 2 2 Tho complex subunit 7 APG17 PF04108.12 OAF99590.1 - 0.0092 15.1 0.3 0.037 13.1 0.0 1.8 2 0 0 2 2 2 1 Autophagy protein Apg17 DUF1664 PF07889.12 OAF99590.1 - 0.01 15.9 0.1 4.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 OAF99590.1 - 0.026 14.9 3.9 1.9 8.9 0.3 2.4 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator LMP PF04778.12 OAF99590.1 - 0.034 14.0 0.5 4.3 7.2 0.0 2.2 2 0 0 2 2 2 0 LMP repeated region BST2 PF16716.5 OAF99590.1 - 0.042 14.4 0.8 7.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Syntaxin-6_N PF09177.11 OAF99590.1 - 0.042 14.4 2.9 5.4 7.6 2.9 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Lebercilin PF15619.6 OAF99590.1 - 0.043 13.5 3.8 0.29 10.8 0.5 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Phage_GP20 PF06810.11 OAF99590.1 - 0.081 12.7 3.6 0.98 9.2 0.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 OAF99590.1 - 0.19 12.1 1.1 5.5 7.5 0.0 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ketoacyl-synt PF00109.26 OAF99591.1 - 2.4e-79 266.5 0.0 8.3e-79 264.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAF99591.1 - 9.6e-43 146.9 0.0 1.9e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAF99591.1 - 2e-33 114.9 2.6 2e-33 114.9 2.6 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAF99591.1 - 3.3e-24 85.0 2.4 3.2e-12 46.6 1.1 3.1 3 0 0 3 3 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 OAF99591.1 - 1.2e-23 84.4 0.2 3.7e-21 76.3 0.0 3.4 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 OAF99591.1 - 8.1e-14 51.5 0.0 1.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 OAF99591.1 - 2.5e-07 30.7 0.2 2.9e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 OAF99591.1 - 1.5e-06 28.7 1.2 5.4e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 OAF99591.1 - 1.2e-05 26.1 0.3 0.0012 19.5 0.1 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 OAF99591.1 - 0.00032 20.1 0.1 0.0012 18.3 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.7 OAF99591.1 - 0.048 13.4 0.3 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAF99591.1 - 0.074 12.9 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 OAF99591.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RHH_3 PF12651.7 OAF99591.1 - 0.11 12.5 0.2 0.87 9.6 0.0 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix domain Hydrolase_4 PF12146.8 OAF99591.1 - 0.12 11.6 0.1 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 OAF99593.1 - 9.3e-09 35.3 14.2 2.2e-08 34.1 14.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAF99593.1 - 3.1e-05 23.1 0.1 0.00023 20.3 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAF99593.1 - 3.2e-05 24.1 13.5 0.00012 22.3 1.8 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAF99593.1 - 0.00027 21.2 3.9 0.00027 21.2 3.9 4.3 3 1 1 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAF99593.1 - 0.0059 17.4 1.0 0.0059 17.4 1.0 4.4 4 1 0 4 4 4 2 C2H2-type zinc finger adh_short_C2 PF13561.6 OAF99594.1 - 2.1e-54 184.6 1.9 3.2e-54 184.0 1.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAF99594.1 - 4.7e-48 163.2 5.9 5.8e-48 162.9 5.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAF99594.1 - 2.7e-09 37.2 1.5 3.7e-09 36.7 1.5 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAF99594.1 - 0.0051 16.1 0.1 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1372 PF07116.11 OAF99594.1 - 0.0063 16.7 0.9 0.012 15.7 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1372) NAD_binding_2 PF03446.15 OAF99594.1 - 0.017 15.3 1.0 0.03 14.5 0.9 1.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_60s PF00428.19 OAF99595.1 - 0.0077 16.8 3.7 0.053 14.1 4.2 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF5302 PF17227.2 OAF99595.1 - 0.11 13.4 0.1 0.42 11.7 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5302) F-box PF00646.33 OAF99596.1 - 1.7e-05 24.5 0.2 6.1e-05 22.8 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAF99596.1 - 0.00014 21.7 0.7 0.00014 21.7 0.7 2.5 3 0 0 3 3 3 1 F-box-like DUF1479 PF07350.12 OAF99596.1 - 0.031 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) DUF4110 PF13422.6 OAF99597.1 - 6.7e-31 106.2 0.7 6.7e-31 106.2 0.7 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 OAF99597.1 - 8e-27 93.0 11.2 2.9e-08 33.6 0.1 6.1 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OAF99597.1 - 1.2e-23 82.7 6.3 6.9e-08 32.3 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OAF99597.1 - 2.1e-21 75.7 14.5 6.7e-07 29.4 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OAF99597.1 - 8.1e-21 73.5 4.0 0.00011 22.4 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OAF99597.1 - 1.4e-15 56.6 6.4 7.9e-06 25.4 0.1 5.2 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OAF99597.1 - 1.3e-11 44.0 6.0 0.067 13.2 0.2 6.1 5 1 0 5 5 5 4 Kelch motif BUD22 PF09073.10 OAF99597.1 - 0.00063 19.2 13.7 0.00063 19.2 13.7 2.2 2 0 0 2 2 2 1 BUD22 CENP-B_dimeris PF09026.10 OAF99597.1 - 6.3 7.3 25.2 1.4 9.4 0.4 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Abhydrolase_1 PF00561.20 OAF99598.1 - 3.3e-13 49.9 0.0 5.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAF99598.1 - 8.5e-09 35.0 0.0 1.9e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAF99598.1 - 0.018 14.7 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 OAF99598.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family FAD_binding_3 PF01494.19 OAF99599.1 - 8.5e-13 48.3 4.5 1.6e-10 40.8 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAF99599.1 - 1.6e-05 25.0 1.5 4.5e-05 23.6 1.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAF99599.1 - 2e-05 24.6 1.0 0.03 14.3 0.4 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 OAF99599.1 - 0.00026 20.7 4.2 0.00063 19.4 4.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAF99599.1 - 0.00028 20.2 2.0 0.0016 17.7 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAF99599.1 - 0.00079 18.6 0.0 0.0031 16.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 OAF99599.1 - 0.01 15.2 0.4 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAF99599.1 - 0.044 14.3 1.3 0.13 12.8 1.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAF99599.1 - 0.11 11.2 0.2 0.19 10.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Peptidase_C15 PF01470.17 OAF99600.1 - 1.5e-13 51.4 0.0 1.1e-07 32.2 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase p450 PF00067.22 OAF99601.1 - 2.3e-76 257.4 0.0 3e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dimer_Tnp_hAT PF05699.14 OAF99601.1 - 2e-13 49.9 0.1 5e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ketoacyl-synt PF00109.26 OAF99602.1 - 1.3e-74 251.0 0.5 2.5e-74 250.1 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAF99602.1 - 6.7e-73 246.0 0.2 1.2e-72 245.1 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 OAF99602.1 - 5.7e-58 195.8 1.3 8.4e-58 195.2 0.5 1.7 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 OAF99602.1 - 2.1e-37 127.7 0.2 5.4e-37 126.4 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 OAF99602.1 - 1.3e-15 57.4 0.1 7e-15 55.0 0.1 2.2 1 1 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 OAF99602.1 - 1e-13 51.7 0.0 3.1e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 OAF99602.1 - 4.3e-11 43.0 0.0 1.3e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OAF99602.1 - 8.6e-11 41.7 0.1 2.6e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99602.1 - 0.00033 20.3 0.1 0.00033 20.3 0.1 3.2 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 OAF99602.1 - 0.0057 15.8 0.1 0.0094 15.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 OAF99602.1 - 0.018 14.4 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF4112 PF13430.6 OAF99603.1 - 0.092 13.0 2.4 2.4 8.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Cupin_2 PF07883.11 OAF99604.1 - 2.9e-08 33.3 0.6 6.1e-08 32.3 0.6 1.5 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.25 OAF99605.1 - 1.3e-19 70.4 0.0 7.4e-15 54.9 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99605.1 - 1.9e-06 27.6 0.0 1.5e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAF99605.1 - 0.00026 21.0 0.3 0.00038 20.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAF99605.1 - 0.054 13.0 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAF99605.1 - 0.082 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Herpes_U34 PF04541.13 OAF99605.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 MBOAT_2 PF13813.6 OAF99606.1 - 2.7e-19 69.2 2.4 5.8e-19 68.2 2.4 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 OAF99607.1 - 1.6e-61 208.5 0.0 2.1e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 OAF99608.1 - 1e-11 44.7 7.1 1.8e-11 44.0 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAF99608.1 - 1.5e-10 40.6 0.0 3.7e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.14 OAF99609.1 - 1.8e-40 139.6 3.3 2e-40 139.4 3.3 1.0 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 OAF99610.1 - 3.9e-37 128.0 46.9 3.9e-37 128.0 46.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAF99610.1 - 4.6e-13 48.5 18.5 9.5e-13 47.4 18.5 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4516 PF14990.6 OAF99610.1 - 4.4 7.1 5.3 12 5.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) UbiA PF01040.18 OAF99611.1 - 1e-35 123.3 16.8 1.3e-35 122.9 16.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Mannosyl_trans4 PF15971.5 OAF99611.1 - 0.017 15.0 2.1 0.042 13.7 2.1 1.7 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase FAD_binding_4 PF01565.23 OAF99612.1 - 2.1e-23 82.6 0.4 4.1e-23 81.7 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain DNA_ligase_C PF17879.1 OAF99612.1 - 0.12 12.4 0.1 0.9 9.6 0.1 2.4 2 1 1 3 3 3 0 DNA ligase C-terminal domain Egh16-like PF11327.8 OAF99613.1 - 1.3e-48 165.9 12.2 1.5e-48 165.7 12.2 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor HemeBinding_Shp PF11545.8 OAF99613.1 - 0.0034 17.4 0.1 0.0054 16.7 0.1 1.5 1 0 0 1 1 1 1 Cell surface heme-binding protein Shp TPP_enzyme_N PF02776.18 OAF99614.1 - 1.7e-29 102.6 0.0 2.8e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAF99614.1 - 4.5e-22 78.3 0.0 8.1e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAF99614.1 - 3.5e-14 52.9 0.0 8.3e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OAF99614.1 - 0.025 13.5 0.2 0.025 13.5 0.2 1.6 2 0 0 2 2 2 0 Dehydrogenase E1 component Pkinase PF00069.25 OAF99615.1 - 5.9e-64 216.0 0.0 8.4e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF99615.1 - 4.4e-45 154.0 0.0 7.5e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAF99615.1 - 6e-10 38.9 0.0 4.8e-07 29.4 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 OAF99615.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAF99615.1 - 0.022 13.6 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAF99615.1 - 0.082 12.8 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family baeRF_family2 PF18844.1 OAF99616.1 - 0.12 12.5 2.6 0.26 11.3 1.3 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Tyrosinase PF00264.20 OAF99617.1 - 1e-43 150.2 0.6 1.7e-43 149.5 0.6 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAF99617.1 - 8.6e-22 78.1 0.0 8.2e-20 71.7 0.0 2.4 1 1 0 1 1 1 1 Tyosinase C-terminal domain DnaJ PF00226.31 OAF99618.1 - 1.5e-22 79.5 0.4 1.5e-22 79.5 0.4 2.7 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 OAF99618.1 - 1.6e-10 41.0 5.5 1.6e-10 41.0 5.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAF99618.1 - 2.3e-10 40.7 2.3 1.1e-06 28.9 0.7 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OAF99618.1 - 1.7e-07 31.4 2.0 1.7e-07 31.4 2.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAF99618.1 - 0.0012 19.5 6.0 0.24 12.4 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 OAF99618.1 - 0.0021 18.5 0.9 0.18 12.2 0.3 3.4 3 0 0 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 OAF99618.1 - 0.031 14.7 8.3 0.96 10.0 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 OAF99618.1 - 0.19 11.7 0.9 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 OAF99618.1 - 0.25 11.8 1.2 2 9.0 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain SPX PF03105.19 OAF99619.1 - 2.7e-51 175.7 4.4 7.3e-51 174.3 4.4 1.7 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 OAF99619.1 - 1.5e-07 31.5 10.8 2.7e-07 30.6 8.8 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAF99619.1 - 1.9e-06 27.6 9.2 3.5e-06 26.8 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAF99619.1 - 4.7e-06 26.5 9.4 1.9e-05 24.5 9.5 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAF99619.1 - 1.6e-05 24.7 9.5 3.4e-05 23.6 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAF99619.1 - 2.3e-05 24.3 6.1 5.4e-05 23.1 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAF99619.1 - 2.9e-05 23.8 10.3 6.5e-05 22.7 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAF99619.1 - 6.7e-05 23.1 10.8 0.00012 22.3 10.4 1.7 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAF99619.1 - 0.00026 20.8 10.0 0.0017 18.2 10.5 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Utp13 PF08625.11 OAF99619.1 - 0.0071 16.3 0.0 0.18 11.7 0.0 2.6 3 0 0 3 3 3 1 Utp13 specific WD40 associated domain DUF1660 PF07874.11 OAF99619.1 - 0.033 14.7 1.5 0.13 12.8 1.5 2.1 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-RING_4 PF14570.6 OAF99619.1 - 0.066 13.0 10.3 0.49 10.2 10.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF4936 PF16290.5 OAF99619.1 - 0.093 13.4 0.3 0.55 11.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) TerY_C PF15616.6 OAF99619.1 - 0.095 12.8 0.9 0.18 11.9 0.9 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain DUF3782 PF12644.7 OAF99619.1 - 0.13 12.4 0.5 0.56 10.4 0.0 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF3782) KinB_sensor PF16767.5 OAF99619.1 - 0.25 11.8 1.9 0.48 10.9 0.6 2.1 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB zf-ANAPC11 PF12861.7 OAF99619.1 - 0.26 11.4 5.8 0.7 10.0 5.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OAF99619.1 - 0.74 9.7 4.6 0.74 9.7 3.1 1.7 2 0 0 2 2 1 0 zf-RING of BARD1-type protein TnpV PF14198.6 OAF99619.1 - 0.94 9.5 6.4 0.21 11.6 0.3 2.9 4 0 0 4 4 4 0 Transposon-encoded protein TnpV zf-rbx1 PF12678.7 OAF99619.1 - 1.6 9.1 10.8 6.5 7.1 10.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAF99623.1 - 4.4e-10 39.7 6.2 8e-10 38.9 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAF99623.1 - 2.2e-07 30.7 5.9 3.6e-07 30.0 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAF99623.1 - 2.8e-07 30.4 1.8 5.5e-07 29.5 1.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAF99623.1 - 3.7e-07 29.9 5.0 7.1e-07 29.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAF99623.1 - 9.9e-06 25.8 4.8 2.1e-05 24.7 4.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAF99623.1 - 3.1e-05 23.8 3.2 5.2e-05 23.0 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 OAF99623.1 - 6.2e-05 22.5 0.0 9.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 OAF99623.1 - 0.00035 20.4 4.9 0.00079 19.2 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAF99623.1 - 0.00046 20.2 1.6 0.00091 19.2 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAF99623.1 - 0.00078 19.1 2.4 0.0016 18.1 2.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger FYVE PF01363.21 OAF99623.1 - 0.00091 19.3 2.7 0.0016 18.6 2.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_4 PF14447.6 OAF99623.1 - 0.0013 18.6 3.7 0.0025 17.6 3.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OAF99623.1 - 0.0031 17.3 2.1 0.006 16.4 2.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OAF99623.1 - 0.026 14.7 3.8 0.12 12.6 3.8 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF2526 PF10735.9 OAF99623.1 - 0.042 14.0 0.2 0.14 12.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) zf-Nse PF11789.8 OAF99623.1 - 0.077 12.8 1.0 0.14 12.0 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.11 OAF99623.1 - 0.3 11.0 1.5 0.54 10.2 1.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Zn_ribbon_17 PF17120.5 OAF99623.1 - 0.4 10.3 8.4 0.076 12.6 4.1 1.9 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OAF99623.1 - 0.45 10.7 4.5 0.85 9.8 4.5 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 OAF99623.1 - 0.8 9.9 4.7 3.2 8.0 4.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Med9 PF07544.13 OAF99624.1 - 4.6e-18 65.1 1.5 8.2e-18 64.3 1.5 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 OAF99624.1 - 3.4e-05 24.1 0.9 4.8e-05 23.6 0.9 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DivIC PF04977.15 OAF99624.1 - 0.037 13.8 1.0 0.051 13.4 0.6 1.4 1 1 0 1 1 1 0 Septum formation initiator Spc29 PF17082.5 OAF99624.1 - 0.088 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Spc24 PF08286.11 OAF99624.1 - 0.17 12.1 0.2 0.29 11.4 0.2 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 iPGM_N PF06415.13 OAF99625.1 - 5.3e-77 258.1 0.0 1e-76 257.2 0.0 1.5 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 OAF99625.1 - 6.1e-74 248.5 0.1 7.1e-74 248.3 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 OAF99625.1 - 9.7e-06 25.4 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAF99625.1 - 3.8e-05 23.3 0.0 0.0011 18.4 0.0 2.6 2 1 0 2 2 2 1 Sulfatase PglZ PF08665.12 OAF99625.1 - 0.0044 17.1 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 PglZ domain Alk_phosphatase PF00245.20 OAF99625.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase AP_endonuc_2 PF01261.24 OAF99625.1 - 0.082 12.3 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Arm-DNA-bind_2 PF12167.8 OAF99625.1 - 0.1 12.5 0.2 4.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Arm DNA-binding domain Pkinase PF00069.25 OAF99626.1 - 8.2e-71 238.4 0.0 9.9e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAF99626.1 - 1.2e-27 96.9 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAF99626.1 - 6.5e-07 28.9 0.0 9.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAF99626.1 - 0.00015 20.7 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAF99626.1 - 0.00035 20.6 0.4 0.00073 19.5 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAF99626.1 - 0.00052 19.4 0.1 0.00091 18.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 OAF99628.1 - 2e-32 112.5 45.8 1.8e-31 109.4 44.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAF99628.1 - 5e-11 42.1 4.7 5e-11 42.1 4.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Ras PF00071.22 OAF99629.1 - 4e-40 137.1 0.0 4.8e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAF99629.1 - 3.4e-12 46.6 0.0 4.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAF99629.1 - 2.8e-05 23.6 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAF99629.1 - 0.0053 16.8 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAF99629.1 - 0.013 15.1 0.0 0.15 11.6 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 OAF99629.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.18 OAF99629.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Mito_carr PF00153.27 OAF99630.1 - 1.3e-61 204.5 2.5 1.2e-20 73.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PBP PF01161.20 OAF99632.1 - 2.5e-11 44.0 0.1 3.1e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Phage_TTP_1 PF04630.12 OAF99633.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail tube protein NAD_binding_8 PF13450.6 OAF99634.1 - 3.4e-12 46.4 0.1 2.4e-11 43.7 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAF99634.1 - 6.5e-05 22.3 0.0 0.00046 19.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAF99634.1 - 0.00015 20.9 0.1 0.00033 19.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAF99634.1 - 0.00021 20.7 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAF99634.1 - 0.00023 20.0 0.0 0.00034 19.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 OAF99634.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAF99634.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAF99634.1 - 0.0026 17.4 0.3 0.005 16.5 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAF99634.1 - 0.0038 17.2 0.0 0.0097 15.9 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAF99634.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAF99634.1 - 0.046 13.0 0.2 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAF99634.1 - 0.081 13.5 0.1 0.4 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAF99634.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.19 OAF99634.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase KH_1 PF00013.29 OAF99634.1 - 0.52 10.2 1.7 3.2 7.7 0.2 2.7 3 0 0 3 3 3 0 KH domain OmdA PF13376.6 OAF99635.1 - 4.6e-17 61.8 0.9 4.6e-17 61.8 0.9 2.4 3 0 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated Herpes_LAMP2 PF06126.11 OAF99635.1 - 0.056 12.1 0.0 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 SCIMP PF15050.6 OAF99635.1 - 0.16 12.5 0.4 0.24 11.9 0.4 1.3 1 0 0 1 1 1 0 SCIMP protein adh_short PF00106.25 OAF99636.1 - 7.4e-17 61.4 0.1 4e-12 46.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99636.1 - 6.5e-10 39.0 0.1 5.2e-05 22.9 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAF99636.1 - 3.5e-05 23.8 0.1 5.8e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAF99636.1 - 0.026 14.0 0.2 0.071 12.6 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAF99636.1 - 0.18 11.4 0.1 0.32 10.5 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family Peptidase_S41 PF03572.18 OAF99637.1 - 6.7e-06 25.8 0.0 1.7e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 MF_alpha_N PF05436.11 OAF99638.1 - 0.15 11.9 0.4 0.27 11.2 0.4 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Arm-DNA-bind_4 PF14657.6 OAF99638.1 - 2 8.2 5.2 1.7 8.4 1.6 2.4 1 1 1 2 2 2 0 Arm DNA-binding domain SMC_N PF02463.19 OAF99639.1 - 3.2e-74 249.1 7.2 6.8e-74 248.0 7.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAF99639.1 - 2.6e-23 82.6 0.0 1e-22 80.6 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAF99639.1 - 2e-12 47.6 0.0 1.7e-05 24.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Myosin_tail_1 PF01576.19 OAF99639.1 - 0.00014 19.9 38.9 0.00014 19.9 38.9 4.0 2 2 2 4 4 4 3 Myosin tail AAA_29 PF13555.6 OAF99639.1 - 0.00042 20.0 0.0 0.0009 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OAF99639.1 - 0.034 14.4 0.4 11 6.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 OAF99639.1 - 0.064 13.5 0.1 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 OAF99639.1 - 0.95 10.0 0.0 0.95 10.0 0.0 6.2 5 2 0 5 5 5 0 ABC transporter NmrA PF05368.13 OAF99640.1 - 7.1e-25 87.9 0.1 1.3e-24 87.1 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAF99640.1 - 1.1e-08 35.2 0.3 1.9e-08 34.4 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAF99640.1 - 2.8e-05 23.7 0.3 0.0049 16.4 0.1 2.6 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAF99640.1 - 0.00037 19.6 0.2 0.00056 19.0 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family B3 PF02362.21 OAF99640.1 - 0.1 12.5 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 B3 DNA binding domain Semialdhyde_dh PF01118.24 OAF99640.1 - 0.15 12.5 0.1 0.29 11.6 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Bys1 PF04681.12 OAF99641.1 - 2.4e-07 30.8 0.0 2.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein MAPEG PF01124.18 OAF99643.1 - 7.7e-19 67.9 0.5 8.8e-19 67.7 0.5 1.0 1 0 0 1 1 1 1 MAPEG family UPF0203 PF05254.12 OAF99644.1 - 6.4e-27 93.6 1.9 7.5e-27 93.4 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 OAF99644.1 - 0.00067 19.8 2.3 0.082 13.1 0.1 2.2 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 OAF99644.1 - 0.00079 19.7 0.4 0.00079 19.7 0.4 2.1 2 1 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 OAF99644.1 - 0.004 17.1 3.7 0.23 11.5 0.2 2.5 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF5339 PF17274.2 OAF99644.1 - 0.25 12.2 6.9 2.3 9.2 2.4 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5339) DNA_pol_A_exo1 PF01612.20 OAF99645.1 - 9.1e-40 136.2 0.1 1.5e-39 135.5 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OAF99645.1 - 8.5e-23 80.9 0.0 2.1e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 OAF99645.1 - 1.3e-12 47.5 0.0 3.7e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 HRDC domain DUF3767 PF12597.8 OAF99647.1 - 3.3e-24 84.6 0.1 3.3e-24 84.6 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) Enterotoxin_HS1 PF08090.11 OAF99647.1 - 0.023 14.6 1.5 0.05 13.6 1.5 1.5 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 SHR3_chaperone PF08229.11 OAF99647.1 - 0.025 13.6 0.7 0.046 12.7 0.4 1.5 1 1 0 1 1 1 0 ER membrane protein SH3 DUF1744 PF08490.12 OAF99648.1 - 6.2e-152 505.8 0.0 9e-152 505.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OAF99648.1 - 4.5e-82 275.9 0.7 4.5e-82 275.9 0.7 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OAF99648.1 - 2.9e-15 55.9 1.4 3.1e-12 46.0 0.2 3.6 2 2 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OAF99648.1 - 2.4e-10 40.4 0.1 7.5e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OAF99648.1 - 4.7e-06 26.7 0.1 4.1e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 RNase_H superfamily Zn_clus PF00172.18 OAF99650.1 - 1.5e-07 31.4 11.9 1.5e-07 31.4 11.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAF99650.1 - 3.2e-05 22.9 1.8 0.0033 16.3 1.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain eIF3m_C_helix PF18005.1 OAF99650.1 - 2.1 8.1 5.3 4.2 7.1 5.3 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix AnmK PF03702.14 OAF99651.1 - 2.8e-24 85.9 0.0 7.7e-24 84.5 0.0 1.6 1 1 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FGGY_C PF02782.16 OAF99651.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain A_thal_3526 PF09713.10 OAF99651.1 - 0.082 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) VHS PF00790.19 OAF99652.1 - 1.4e-47 161.1 0.1 4.5e-47 159.4 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 OAF99652.1 - 1.2e-21 76.8 2.8 2.1e-21 76.0 0.1 2.8 3 0 0 3 3 3 1 GAT domain Alpha_adaptinC2 PF02883.20 OAF99652.1 - 4.2e-20 72.1 3.0 1e-19 70.9 3.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 OAF99652.1 - 5e-08 32.4 0.1 2.9e-06 26.8 0.0 3.2 3 0 0 3 3 3 1 GGA N-GAT domain DUF5344 PF17279.2 OAF99652.1 - 0.14 12.7 1.3 0.57 10.8 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5344) AAA PF00004.29 OAF99653.1 - 6.7e-19 68.6 0.0 1.5e-18 67.5 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAF99653.1 - 1.2e-05 25.8 0.0 3.5e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OAF99653.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAF99653.1 - 0.00059 20.1 0.4 0.056 13.7 0.0 3.1 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 OAF99653.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 OAF99653.1 - 0.015 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAF99653.1 - 0.016 14.5 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 OAF99653.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAF99653.1 - 0.087 13.4 0.1 0.36 11.4 0.0 2.1 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 OAF99653.1 - 0.095 12.1 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAF99653.1 - 0.097 12.0 1.9 0.16 11.3 0.1 2.2 3 0 0 3 3 3 0 KaiC DnaB_C PF03796.15 OAF99653.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 OAF99653.1 - 0.13 12.3 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Actin PF00022.19 OAF99654.1 - 8.1e-138 459.4 0.0 9.1e-138 459.3 0.0 1.0 1 0 0 1 1 1 1 Actin MBOAT PF03062.19 OAF99655.1 - 3.4e-41 141.7 12.7 3.4e-41 141.7 12.7 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Proteasome PF00227.26 OAF99656.1 - 1.8e-46 158.0 0.1 2.4e-46 157.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 OAF99656.1 - 2.7e-14 52.3 2.0 2.7e-14 52.3 2.0 1.9 3 0 0 3 3 3 1 Proteasome beta subunits C terminal Aquarius_N PF16399.5 OAF99656.1 - 0.12 10.4 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus NUP214 PF16755.5 OAF99657.1 - 4e-06 26.3 0.0 0.00043 19.6 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 OAF99657.1 - 0.0097 16.2 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3486 PF11985.8 OAF99657.1 - 0.24 11.8 3.2 1.6 9.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) SDA1 PF05285.12 OAF99657.1 - 5.6 6.3 8.9 1.1 8.6 2.8 2.0 2 0 0 2 2 2 0 SDA1 TBPIP PF07106.13 OAF99658.1 - 1.4e-17 63.3 0.2 2.8e-16 59.2 0.0 2.2 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain CDC73_N PF16050.5 OAF99658.1 - 0.038 13.3 6.1 0.39 10.0 3.9 2.7 1 1 1 2 2 2 0 Paf1 complex subunit CDC73 N-terminal DUF1889 PF08986.10 OAF99658.1 - 0.038 14.4 0.3 4 7.9 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1889) DHR10 PF18595.1 OAF99658.1 - 0.051 13.6 0.5 0.051 13.6 0.5 2.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DUF4253 PF14062.6 OAF99658.1 - 0.07 13.3 1.4 2.4 8.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4253) ZapB PF06005.12 OAF99658.1 - 0.13 12.7 0.5 0.13 12.7 0.5 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Seadorna_VP6 PF07407.11 OAF99658.1 - 0.16 10.9 0.5 0.2 10.6 0.5 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein PGA2 PF07543.12 OAF99658.1 - 0.37 10.8 8.5 0.03 14.3 2.6 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Sun2_CC2 PF18580.1 OAF99658.1 - 1.1 9.5 5.5 12 6.2 0.0 3.7 3 2 1 4 4 4 0 SUN2 coiled coil domain 2 Seryl_tRNA_N PF02403.22 OAF99658.1 - 1.9 8.8 6.7 1.2 9.4 0.6 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sel1 PF08238.12 OAF99659.1 - 1.7e-21 76.2 21.8 9.3e-08 32.5 0.0 7.1 6 1 1 7 7 7 6 Sel1 repeat TPR_1 PF00515.28 OAF99659.1 - 0.0015 18.3 0.7 0.38 10.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat HisKA_2 PF07568.12 OAF99659.1 - 0.086 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase ASF1_hist_chap PF04729.13 OAF99660.1 - 8.2e-73 243.4 0.0 1.1e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone BUD22 PF09073.10 OAF99660.1 - 3.7 6.8 18.0 4.7 6.5 18.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAF99660.1 - 4.1 5.5 20.3 5.2 5.2 20.3 1.0 1 0 0 1 1 1 0 Nop14-like family PMSI1 PF15322.6 OAF99660.1 - 6.5 6.1 11.2 9 5.6 11.2 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative ATG22 PF11700.8 OAF99661.1 - 2.8e-199 662.7 12.9 3.4e-199 662.4 12.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAF99661.1 - 3.1e-07 29.7 52.5 1.2e-05 24.4 20.5 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Pex24p PF06398.11 OAF99661.1 - 2.4 7.1 8.6 0.31 10.0 0.5 2.3 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Med14 PF08638.11 OAF99662.1 - 7.9e-52 175.5 0.1 1.5e-51 174.6 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Takusan PF04822.13 OAF99662.1 - 0.14 12.1 0.4 0.51 10.2 0.4 1.9 1 0 0 1 1 1 0 Takusan U1snRNP70_N PF12220.8 OAF99663.1 - 0.04 14.6 2.2 0.05 14.2 2.2 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HEPN_AbiU2 PF18734.1 OAF99663.1 - 0.065 12.7 0.1 0.078 12.5 0.1 1.1 1 0 0 1 1 1 0 AbiU2 MDH PF02315.16 OAF99663.1 - 0.12 12.4 0.2 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit RMI1_N PF08585.12 OAF99664.1 - 2e-57 194.4 0.0 2.4e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Vps51 PF08700.11 OAF99665.1 - 1.1e-32 112.0 0.0 2.6e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 OAF99665.1 - 0.00042 20.5 0.1 0.00082 19.6 0.1 1.5 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Synaphin PF05835.12 OAF99665.1 - 0.027 14.7 4.9 2.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Synaphin protein Dor1 PF04124.12 OAF99665.1 - 0.057 12.1 0.7 0.072 11.8 0.0 1.6 2 0 0 2 2 2 0 Dor1-like family Mpv17_PMP22 PF04117.12 OAF99667.1 - 5.4e-16 58.6 0.4 1e-15 57.7 0.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3576 PF12100.8 OAF99667.1 - 0.093 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) Hexokinase_2 PF03727.16 OAF99668.1 - 2.2e-74 249.9 0.0 3.3e-74 249.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAF99668.1 - 6.6e-68 228.5 0.0 1.1e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Glyco_hydro_61 PF03443.14 OAF99669.1 - 3.8e-53 180.5 0.0 4.5e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.24 OAF99671.1 - 3.3e-125 418.5 25.4 3.7e-125 418.3 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99671.1 - 1.7e-21 76.6 38.0 2.1e-19 69.7 34.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4818 PF16089.5 OAF99671.1 - 0.19 12.2 5.9 0.24 11.9 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4818) DUF5357 PF17310.2 OAF99671.1 - 0.2 10.2 5.8 3.1 6.3 2.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5357) DUF2070 PF09843.9 OAF99671.1 - 0.56 8.4 7.0 1.1 7.4 7.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4064 PF13273.6 OAF99671.1 - 2.7 8.3 23.8 2.8 8.2 6.5 4.8 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) RNA_pol_Rpc4 PF05132.14 OAF99672.1 - 0.027 14.9 10.6 0.031 14.7 10.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2151 PF10221.9 OAF99672.1 - 0.031 12.9 4.7 0.035 12.7 4.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Apt1 PF10351.9 OAF99672.1 - 0.031 13.1 3.7 0.036 12.9 3.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2052 PF09747.9 OAF99672.1 - 0.031 14.4 14.7 0.036 14.2 14.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SAPS PF04499.15 OAF99672.1 - 0.036 12.9 2.2 0.034 12.9 2.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PTPRCAP PF15713.5 OAF99672.1 - 0.04 14.2 18.9 0.05 13.9 18.9 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4820 PF16091.5 OAF99672.1 - 0.067 12.5 4.5 0.073 12.4 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4050 PF13259.6 OAF99672.1 - 0.15 12.4 6.5 0.19 12.0 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DDHD PF02862.17 OAF99672.1 - 0.16 12.1 2.6 0.17 12.1 2.6 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 OAF99672.1 - 0.23 11.6 9.8 0.29 11.3 9.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 OAF99672.1 - 0.58 10.6 11.4 0.75 10.3 11.4 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MCM_bind PF09739.9 OAF99672.1 - 0.6 8.5 10.6 0.73 8.2 10.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PRP38_assoc PF12871.7 OAF99672.1 - 0.68 10.6 15.9 0.97 10.1 15.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Paramyxo_ncap PF00973.19 OAF99672.1 - 0.84 8.5 6.6 1 8.2 6.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Neur_chan_memb PF02932.16 OAF99672.1 - 2.6 8.0 4.1 2.9 7.9 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 OAF99672.1 - 3.2 7.0 17.1 4 6.7 17.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF5427 PF10310.9 OAF99672.1 - 3.6 6.4 15.5 4.1 6.2 15.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Auts2 PF15336.6 OAF99672.1 - 3.8 7.6 11.3 4.8 7.3 11.3 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Nop53 PF07767.11 OAF99672.1 - 3.9 6.8 25.3 4.7 6.5 25.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PPL5 PF18168.1 OAF99672.1 - 4 6.7 11.8 5.2 6.3 11.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF2722 PF10846.8 OAF99672.1 - 4.3 6.2 12.3 5.3 5.9 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SLC12 PF03522.15 OAF99672.1 - 4.4 6.2 9.0 4.9 6.1 9.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 OAF99672.1 - 4.8 6.1 7.4 5.3 5.9 7.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 OAF99672.1 - 4.9 6.3 7.1 5.4 6.1 7.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 OAF99672.1 - 5 6.5 14.7 5.8 6.3 14.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4407 PF14362.6 OAF99672.1 - 5.6 6.2 6.2 6.4 6.0 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 OAF99672.1 - 5.6 5.0 8.0 6.4 4.8 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 OAF99672.1 - 5.7 6.7 19.5 6.6 6.5 19.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF3_subunit PF08597.10 OAF99672.1 - 5.9 6.7 28.3 7.5 6.4 28.3 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CLN3 PF02487.17 OAF99672.1 - 6.5 5.7 6.4 7.6 5.5 6.4 1.0 1 0 0 1 1 1 0 CLN3 protein CDC27 PF09507.10 OAF99672.1 - 7.8 5.8 23.5 9.7 5.5 23.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Presenilin PF01080.17 OAF99672.1 - 8.8 5.0 13.2 11 4.7 13.2 1.0 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 OAF99672.1 - 9.1 4.9 16.4 11 4.7 16.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 OAF99672.1 - 9.5 4.2 11.9 11 4.0 11.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Lactamase_B PF00753.27 OAF99673.1 - 1.3e-06 28.5 0.3 5.8e-05 23.2 0.1 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAF99673.1 - 0.00051 19.6 0.0 0.0022 17.6 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NAD_binding_6 PF08030.12 OAF99674.1 - 7.6e-33 113.8 0.0 1.6e-32 112.8 0.0 1.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAF99674.1 - 1.7e-21 76.3 0.0 4.1e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OAF99674.1 - 1.6e-15 57.3 13.1 1.6e-15 57.3 13.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 OAF99674.1 - 0.084 13.2 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAF99674.1 - 0.14 12.8 0.0 0.43 11.3 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain GWT1 PF06423.12 OAF99674.1 - 0.66 10.1 3.2 1.5 8.9 0.1 2.7 3 0 0 3 3 3 0 GWT1 adh_short_C2 PF13561.6 OAF99675.1 - 6.2e-55 186.3 1.5 7.7e-55 186.0 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAF99675.1 - 1.4e-46 158.4 0.8 1.7e-46 158.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAF99675.1 - 2.3e-12 47.2 0.7 3.6e-12 46.6 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAF99675.1 - 0.00035 20.1 0.2 0.00069 19.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAF99675.1 - 0.0025 17.1 0.1 0.0048 16.2 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EMG1 PF03587.14 OAF99676.1 - 4.7e-76 254.8 0.0 5.5e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Rick_17kDa_Anti PF05433.15 OAF99677.1 - 7.8 6.5 14.5 3.8 7.4 9.6 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain MFS_1 PF07690.16 OAF99679.1 - 5.5e-27 94.6 17.9 5.5e-27 94.6 17.9 2.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Arr-ms PF12120.8 OAF99679.1 - 0.16 12.2 0.0 0.57 10.4 0.0 1.8 2 0 0 2 2 2 0 Rifampin ADP-ribosyl transferase Methyltransf_23 PF13489.6 OAF99680.1 - 3.3e-16 59.6 0.0 6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAF99680.1 - 7.8e-09 36.1 0.0 1.5e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAF99680.1 - 1.9e-07 31.7 0.0 8.2e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAF99680.1 - 5.3e-07 29.5 0.0 3.2e-05 23.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAF99680.1 - 1.5e-05 25.6 0.0 2.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAF99680.1 - 0.00056 19.3 0.0 0.0028 17.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OAF99680.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OAF99680.1 - 0.00092 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAF99680.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 OAF99680.1 - 0.0032 16.4 0.0 0.023 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 OAF99680.1 - 0.0049 16.6 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 OAF99680.1 - 0.0052 16.9 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 OAF99680.1 - 0.0083 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 OAF99680.1 - 0.03 13.7 0.0 0.066 12.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) KGG PF10685.9 OAF99681.1 - 1.5e-20 72.8 6.7 7e-10 38.8 0.1 3.3 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif UDG PF03167.19 OAF99682.1 - 2.7e-21 76.2 0.1 4.6e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Cu_bind_like PF02298.17 OAF99683.1 - 0.05 13.6 1.1 0.81 9.7 1.1 2.2 1 1 0 1 1 1 0 Plastocyanin-like domain DUF3933 PF13069.6 OAF99683.1 - 0.091 12.6 0.1 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Sugar_tr PF00083.24 OAF99684.1 - 3.2e-125 418.5 22.2 7.6e-125 417.3 22.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99684.1 - 1.2e-30 106.7 51.5 7.3e-28 97.5 28.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAF99684.1 - 1.8e-06 26.7 10.3 4.3e-06 25.4 4.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 OAF99684.1 - 5.2e-05 22.3 0.5 0.00017 20.7 0.1 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 OAF99684.1 - 0.0081 14.6 4.1 0.015 13.7 1.6 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 OAF99684.1 - 0.16 10.8 17.5 1.4 7.6 8.5 3.4 2 2 1 3 3 3 0 MFS_1 like family RQC PF09382.10 OAF99685.1 - 3.7e-20 71.8 0.0 7.6e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 OAF99685.1 - 3.5e-19 69.2 0.0 7.6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAF99685.1 - 9.7e-19 67.8 0.0 1.2e-15 57.8 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAF99685.1 - 4.6e-16 59.3 8.7 2.1e-15 57.2 8.7 2.3 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 OAF99685.1 - 2.5e-07 30.8 0.0 9.2e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 OAF99685.1 - 1.1e-06 28.5 0.0 3.5e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 HRDC domain SNF2_N PF00176.23 OAF99685.1 - 0.036 12.8 0.0 0.053 12.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF3952 PF13130.6 OAF99685.1 - 0.058 13.6 0.7 5.3 7.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) SLIDE PF09111.10 OAF99685.1 - 9 6.4 6.6 9.4 6.3 0.2 3.1 3 0 0 3 3 3 0 SLIDE Pyridoxal_deC PF00282.19 OAF99686.1 - 7.9e-25 87.4 0.0 1.6e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAF99686.1 - 0.0025 17.1 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4694 PF15765.5 OAF99686.1 - 0.12 12.4 0.2 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4694) tRNA_m1G_MT PF01746.21 OAF99688.1 - 7.9e-26 91.0 2.6 1.7e-21 76.8 0.0 2.6 3 0 0 3 3 3 2 tRNA (Guanine-1)-methyltransferase GRIM-19 PF06212.12 OAF99689.1 - 7.7e-23 80.9 0.2 2.8e-22 79.1 0.2 1.7 1 1 0 1 1 1 1 GRIM-19 protein adh_short PF00106.25 OAF99691.1 - 3.1e-33 114.9 0.0 4.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99691.1 - 2.3e-28 99.4 0.0 3.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAF99691.1 - 0.0015 18.5 0.0 0.0054 16.7 0.0 1.9 1 1 0 1 1 1 1 KR domain zf-C2H2_4 PF13894.6 OAF99694.1 - 4.6e-05 23.9 10.7 0.12 13.2 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAF99694.1 - 0.00084 19.7 14.4 0.019 15.4 0.1 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAF99694.1 - 0.013 16.1 5.0 0.054 14.1 0.1 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain Cytochrom_B561 PF03188.16 OAF99697.1 - 0.044 13.9 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 Dopey_N PF04118.14 OAF99698.1 - 4e-114 380.8 0.0 9.2e-114 379.7 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal F-box_4 PF15966.5 OAF99700.1 - 0.045 13.6 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 F-box HET PF06985.11 OAF99701.1 - 6.1e-24 85.0 0.0 7.5e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rsa3 PF14615.6 OAF99702.1 - 4.3e-17 61.4 0.1 5.4e-17 61.1 0.1 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TPR_16 PF13432.6 OAF99703.1 - 1.4e-09 38.4 2.3 1.4e-09 38.4 2.3 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAF99703.1 - 7.5e-08 32.6 13.4 0.0056 17.4 0.1 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAF99703.1 - 2.6e-06 27.0 7.5 1.5e-05 24.6 0.6 3.2 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 OAF99703.1 - 1.5e-05 25.4 15.4 0.014 15.9 0.3 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAF99703.1 - 2.2e-05 24.3 6.7 0.005 17.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAF99703.1 - 0.00014 22.2 7.2 1 10.2 0.2 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAF99703.1 - 0.00019 21.3 12.4 0.13 12.5 1.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_22 PF18833.1 OAF99703.1 - 0.00023 21.2 0.0 0.00054 20.1 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3618 PF12277.8 OAF99703.1 - 0.0024 18.1 0.9 0.0088 16.3 0.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) TPR_12 PF13424.6 OAF99703.1 - 0.013 15.7 8.4 0.79 10.0 0.6 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAF99703.1 - 0.014 15.6 3.9 0.18 12.0 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAF99703.1 - 0.057 12.8 3.9 1.3 8.3 0.3 2.2 1 1 1 2 2 2 0 MalT-like TPR region DUF4349 PF14257.6 OAF99703.1 - 0.063 12.7 0.7 0.7 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) ANAPC3 PF12895.7 OAF99703.1 - 0.088 13.1 4.5 3.5 7.9 0.2 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OAF99703.1 - 0.25 11.2 0.1 0.25 11.2 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 OAF99703.1 - 1.8 8.3 14.1 3.5 7.3 6.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 OAF99704.1 - 1.4e-32 110.2 24.8 1.6e-05 24.5 0.0 13.6 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_2 PF07719.17 OAF99704.1 - 2e-31 105.5 36.5 0.0023 17.9 0.2 15.8 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAF99704.1 - 7.9e-30 100.6 23.2 0.0028 17.7 0.1 13.5 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_17 PF13431.6 OAF99704.1 - 1.2e-27 94.3 9.9 0.00033 20.8 0.2 11.2 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAF99704.1 - 6.9e-23 79.4 21.7 0.048 14.5 0.2 14.1 10 4 4 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAF99704.1 - 9.9e-22 77.2 23.5 1.5e-05 25.4 2.2 11.8 11 2 0 12 12 12 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAF99704.1 - 3e-19 69.1 32.5 0.00063 20.0 0.3 12.8 12 2 1 13 13 12 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAF99704.1 - 1.3e-18 66.4 13.6 0.00052 19.6 0.0 11.2 12 1 1 13 13 12 6 TPR repeat TPR_16 PF13432.6 OAF99704.1 - 1.3e-15 57.7 31.6 0.00058 20.5 0.1 11.7 12 2 1 13 13 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAF99704.1 - 4.8e-12 45.0 14.5 0.07 13.2 0.0 11.7 11 1 1 12 12 12 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAF99704.1 - 1.2e-10 41.3 20.7 2 9.2 0.1 12.5 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAF99704.1 - 4.3e-09 36.4 14.5 0.28 11.4 0.0 8.6 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_20 PF14561.6 OAF99704.1 - 0.03 14.7 13.1 6.9 7.1 0.1 6.8 6 1 1 7 7 6 0 Tetratricopeptide repeat FAT PF02259.23 OAF99704.1 - 0.054 12.7 1.8 19 4.4 0.0 3.7 3 1 0 4 4 4 0 FAT domain TPR_10 PF13374.6 OAF99704.1 - 0.059 13.3 22.0 2.3 8.2 0.4 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.10 OAF99704.1 - 0.074 12.0 0.1 22 3.9 0.0 4.0 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TOM6p PF15184.6 OAF99704.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog HemY_N PF07219.13 OAF99704.1 - 0.18 12.0 4.1 56 4.0 0.1 5.0 3 2 2 5 5 5 0 HemY protein N-terminus Flavin_Reduct PF01613.18 OAF99705.1 - 1.9e-25 89.7 0.2 3e-25 89.1 0.2 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF5308 PF17233.2 OAF99705.1 - 0.45 10.7 6.7 89 3.3 6.7 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5308) Afi1 PF07792.12 OAF99705.1 - 0.5 10.9 3.5 0.4 11.2 1.2 1.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Myc_N PF01056.18 OAF99705.1 - 0.71 9.7 5.5 0.3 10.9 2.5 1.8 2 0 0 2 2 2 0 Myc amino-terminal region RNA_pol_Rpc4 PF05132.14 OAF99705.1 - 1.8 9.0 6.8 2.8 8.4 2.2 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 OAF99705.1 - 1.8 7.2 8.5 0.55 8.9 4.4 1.8 2 0 0 2 2 2 0 Presenilin DUF4407 PF14362.6 OAF99705.1 - 2.9 7.2 5.3 0.48 9.7 1.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PAF PF15715.5 OAF99705.1 - 6.4 7.4 11.2 7.9 7.1 3.7 2.3 2 0 0 2 2 2 0 PCNA-associated factor histone like domain Connexin PF00029.19 OAF99705.1 - 8.6 6.0 5.8 2.7 7.7 2.7 1.6 2 0 0 2 2 2 0 Connexin DUF4746 PF15928.5 OAF99705.1 - 8.9 5.6 10.0 20 4.5 10.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ribosomal_L31 PF01197.18 OAF99706.1 - 0.012 15.9 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L31 DUF3545 PF12065.8 OAF99707.1 - 2.1 8.4 6.3 61 3.7 4.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) FA_desaturase PF00487.24 OAF99709.1 - 3.4e-17 63.1 18.4 6.7e-17 62.2 18.4 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAF99709.1 - 6.8e-16 58.2 0.0 1.7e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S10 PF00338.22 OAF99710.1 - 8.5e-26 90.1 0.1 1e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 OAF99711.1 - 1.7e-10 40.4 0.1 4.4e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 CUE domain KH_6 PF15985.5 OAF99713.1 - 0.15 12.4 1.1 8 6.9 0.1 2.3 1 1 1 2 2 2 0 KH domain zf-AN1 PF01428.16 OAF99714.1 - 3.4e-12 46.3 5.2 3.4e-12 46.3 5.2 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.23 OAF99714.1 - 5.3e-09 35.7 0.0 1.2e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 OAF99714.1 - 0.018 15.6 0.0 0.021 15.4 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Acyl-CoA_dh_1 PF00441.24 OAF99715.1 - 1.9e-34 119.0 0.4 3.1e-34 118.3 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 OAF99715.1 - 8.9e-20 70.6 0.0 3.8e-19 68.6 0.0 2.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 OAF99715.1 - 2.3e-16 59.8 0.3 4.2e-16 58.9 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAF99715.1 - 1.3e-07 32.3 0.6 2.8e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAF99715.1 - 4.9e-07 30.1 0.0 1.1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Bromodomain PF00439.25 OAF99716.1 - 1.6e-40 137.1 8.0 1.2e-19 70.2 1.7 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 OAF99716.1 - 4.9e-19 68.4 0.8 1.2e-18 67.1 0.8 1.7 1 0 0 1 1 1 1 BAH domain HTH_32 PF13565.6 OAF99716.1 - 8.2 7.1 6.1 2.6 8.7 1.4 2.8 3 0 0 3 3 3 0 Homeodomain-like domain OTU PF02338.19 OAF99717.1 - 4.5e-05 23.9 0.0 9.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease zf-BED PF02892.15 OAF99717.1 - 0.59 10.2 2.8 0.41 10.7 0.8 1.7 2 0 0 2 2 2 0 BED zinc finger Clathrin PF00637.20 OAF99720.1 - 2.4e-18 66.4 0.2 1.1e-17 64.2 0.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 OAF99720.1 - 0.007 16.3 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAF99720.1 - 0.019 15.0 0.2 0.045 13.8 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 OAF99720.1 - 0.049 13.4 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 OAF99720.1 - 0.057 13.7 0.2 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAF99720.1 - 0.086 12.7 0.3 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4611 PF15387.6 OAF99720.1 - 3.1 8.1 5.9 4.4 7.6 3.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3871 PF12987.7 OAF99721.1 - 0.04 12.7 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) MIF4G_like PF09088.11 OAF99721.1 - 0.081 12.7 0.3 0.85 9.4 0.1 2.1 2 0 0 2 2 2 0 MIF4G like Mog1 PF04603.12 OAF99722.1 - 1.1e-38 132.7 0.0 1.3e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein zf-C2H2_jaz PF12171.8 OAF99723.1 - 1.5e-11 44.2 2.0 3.6e-11 43.1 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAF99723.1 - 2.2e-07 31.1 1.1 5.2e-07 29.8 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAF99723.1 - 0.0074 16.6 1.1 0.013 15.9 1.1 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAF99723.1 - 0.17 12.8 0.3 0.17 12.8 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Aconitase PF00330.20 OAF99724.1 - 6.1e-151 503.5 0.0 7.6e-151 503.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAF99724.1 - 9e-43 145.7 0.0 1.7e-42 144.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Lgl_C PF08596.10 OAF99726.1 - 1.2e-121 406.2 0.0 1.8e-121 405.6 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 OAF99726.1 - 1.5e-06 28.8 0.1 0.056 14.3 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAF99726.1 - 0.00093 19.5 0.0 6.1 7.2 0.0 5.0 4 2 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain FAD_binding_3 PF01494.19 OAF99727.1 - 2.2e-16 60.1 0.0 3.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAF99727.1 - 3e-05 24.2 0.1 0.00011 22.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAF99727.1 - 5.6e-05 22.9 5.7 0.0045 16.6 1.2 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAF99727.1 - 0.00019 20.8 2.9 0.00041 19.7 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAF99727.1 - 0.0005 19.0 3.9 0.052 12.4 1.7 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAF99727.1 - 0.0011 18.3 0.5 0.0018 17.6 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAF99727.1 - 0.0039 16.5 0.7 0.0069 15.7 0.7 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OAF99727.1 - 0.019 15.5 0.1 0.073 13.6 0.2 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAF99727.1 - 0.054 12.8 0.2 0.57 9.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAF99727.1 - 0.061 12.0 0.7 0.1 11.3 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 OAF99727.1 - 0.087 12.8 1.3 0.31 11.0 0.5 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAF99727.1 - 0.16 11.1 2.7 0.27 10.3 2.7 1.3 1 0 0 1 1 1 0 FAD binding domain Lysozyme_like PF13702.6 OAF99728.1 - 0.0054 16.4 1.1 0.015 15.0 1.1 1.6 1 1 0 1 1 1 1 Lysozyme-like SLT PF01464.20 OAF99728.1 - 0.0067 16.1 0.0 0.045 13.4 0.0 1.9 2 0 0 2 2 2 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 OAF99728.1 - 0.11 13.1 0.1 0.32 11.5 0.0 1.9 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase PDCD2_C PF04194.13 OAF99729.1 - 8.1e-47 159.5 0.0 8.5e-46 156.2 0.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain TatD_DNase PF01026.21 OAF99730.1 - 2.5e-39 135.2 0.0 3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Asn_synthase PF00733.21 OAF99731.1 - 3e-62 211.4 0.0 4.2e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 OAF99731.1 - 1.3e-35 122.0 0.0 2.3e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Glyco_hydro_12 PF01670.16 OAF99731.1 - 2.7e-35 122.3 7.8 1.5e-34 119.8 8.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 GATase_6 PF13522.6 OAF99731.1 - 1.2e-31 109.7 0.0 2.7e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAF99731.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein MF_alpha_N PF05436.11 OAF99731.1 - 0.11 12.5 0.3 0.23 11.4 0.3 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus NAD_synthase PF02540.17 OAF99731.1 - 0.2 10.7 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.16 OAF99731.1 - 0.23 10.2 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase SprT-like PF10263.9 OAF99732.1 - 1e-37 128.5 0.1 1.9e-37 127.6 0.1 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 OAF99732.1 - 1.2e-07 31.5 6.0 2.1e-07 30.7 6.0 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 OAF99732.1 - 0.21 11.7 2.5 0.44 10.7 2.5 1.5 1 0 0 1 1 1 0 Zinc ribbon domain TauD PF02668.16 OAF99735.1 - 2.2e-30 106.3 0.1 3.5e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0258 PF06789.12 OAF99735.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) LSM PF01423.22 OAF99736.1 - 1.4e-17 63.1 0.2 1.8e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAF99736.1 - 0.013 15.6 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain MTS PF05175.14 OAF99737.1 - 0.00095 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAF99737.1 - 0.03 15.0 0.0 0.051 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAF99737.1 - 0.12 13.1 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.12 OAF99737.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Complex1_LYR_2 PF13233.6 OAF99738.1 - 2e-21 76.5 0.0 2.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAF99738.1 - 2.6e-12 46.6 0.0 5.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 OAF99738.1 - 0.073 13.7 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Complex1_LYR-like zf-3CxxC_2 PF17180.4 OAF99739.1 - 2 9.2 7.9 2.3 9.0 1.3 3.1 2 1 1 3 3 3 0 Zinc-binding domain Pkr1 PF08636.10 OAF99740.1 - 8.4e-31 105.9 4.4 1.1e-30 105.5 4.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Trypan_PARP PF05887.11 OAF99740.1 - 0.00015 21.7 0.4 0.00024 21.1 0.4 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) FAM176 PF14851.6 OAF99740.1 - 0.091 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 FAM176 family FHIPEP PF00771.20 OAF99740.1 - 0.22 9.9 0.0 0.27 9.6 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family JAB PF01398.21 OAF99741.1 - 7.1e-14 51.8 0.0 1.9e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 OAF99741.1 - 2e-06 28.0 0.7 3.4e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 OAF99741.1 - 0.00018 21.3 0.0 0.00047 19.9 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TFIIF_beta PF02270.15 OAF99741.1 - 0.059 13.5 0.1 0.4 10.9 0.1 2.4 3 0 0 3 3 3 0 TFIIF, beta subunit HTH domain AMMECR1 PF01871.17 OAF99742.1 - 1.1e-46 158.5 0.0 3.5e-46 156.8 0.0 1.8 1 1 0 1 1 1 1 AMMECR1 Ribosomal_L29e PF01779.17 OAF99743.1 - 1.9e-21 76.1 13.2 2.7e-21 75.6 13.2 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family MFS_1 PF07690.16 OAF99745.1 - 2e-32 112.5 31.0 2.3e-31 109.0 33.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 OAF99745.1 - 0.072 13.3 0.7 0.072 13.3 0.7 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) PAF-AH_p_II PF03403.13 OAF99746.1 - 4.7e-11 41.8 0.0 2.8e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAF99746.1 - 1.8e-06 27.1 0.0 3.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAF99746.1 - 0.055 12.5 0.4 1.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Chlorophyllase LIP PF03583.14 OAF99746.1 - 0.11 11.8 0.4 0.43 9.9 0.0 1.8 2 0 0 2 2 2 0 Secretory lipase Glyco_hydro_61 PF03443.14 OAF99748.1 - 5.4e-46 157.1 0.0 8.1e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAF99748.1 - 3.9e-10 39.5 9.6 1.5e-09 37.6 9.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_7 PF00840.20 OAF99749.1 - 1.2e-164 548.2 2.4 1.3e-164 548.0 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 APH PF01636.23 OAF99750.1 - 2.5e-09 37.4 0.1 3.8e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 OAF99750.1 - 0.0083 15.4 0.0 0.05 12.8 0.0 2.0 1 1 0 1 1 1 1 Fructosamine kinase THUMP PF02926.17 OAF99751.1 - 5.9e-14 52.4 0.1 1.5e-13 51.0 0.1 1.7 1 1 1 2 2 2 1 THUMP domain Tma16 PF11176.8 OAF99752.1 - 6.3e-49 165.6 0.7 7.2e-49 165.4 0.4 1.2 1 1 0 1 1 1 1 Translation machinery-associated protein 16 Rab_eff_C PF04698.12 OAF99752.1 - 0.061 11.6 0.5 0.064 11.5 0.5 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus XPG_N PF00752.17 OAF99753.1 - 1.3e-23 83.4 0.0 2.8e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAF99753.1 - 5.1e-23 81.2 0.0 1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OAF99753.1 - 2.8e-05 23.7 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OAF99753.1 - 0.00029 21.4 0.0 0.00076 20.0 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold FancD2 PF14631.6 OAF99754.1 - 5.8 4.2 7.2 6.8 4.0 7.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease S-methyl_trans PF02574.16 OAF99759.1 - 3.2e-71 240.3 0.0 3.6e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase WD40 PF00400.32 OAF99760.1 - 2.1e-47 158.1 17.7 5.2e-09 36.6 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 OAF99760.1 - 4.9e-36 123.8 0.1 6.9e-36 123.4 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 OAF99760.1 - 6.7e-10 39.1 0.1 0.042 14.2 0.0 4.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAF99760.1 - 0.0026 16.5 0.5 1.7 7.2 0.0 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 OAF99760.1 - 0.011 15.0 0.0 0.46 9.7 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 OAF99760.1 - 0.15 11.0 0.0 8.1 5.3 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Erythro-docking PF09277.11 OAF99761.1 - 0.15 12.0 0.9 0.32 10.9 0.9 1.5 1 0 0 1 1 1 0 Erythronolide synthase, docking Med11 PF10280.9 OAF99762.1 - 2.1e-15 57.4 0.0 2.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein DUF2370 PF10176.9 OAF99763.1 - 1.3e-90 303.0 0.0 2.2e-90 302.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) MnhB PF04039.13 OAF99763.1 - 1.6 9.0 5.2 0.45 10.8 0.8 2.1 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter HUN PF08729.10 OAF99766.1 - 2.1e-07 30.8 0.1 3.8e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Nop25 PF09805.9 OAF99766.1 - 0.54 10.7 4.2 1.1 9.8 0.4 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Nop PF01798.18 OAF99768.1 - 1.5e-79 266.7 0.0 1.5e-79 266.7 0.0 2.1 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAF99768.1 - 4.3e-18 65.5 0.0 4.3e-18 65.5 0.0 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain VIR_N PF15912.5 OAF99768.1 - 2.3 7.7 8.3 3.2 7.3 8.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1682 PF07946.14 OAF99768.1 - 5.4 6.1 14.7 43 3.2 13.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Cpn60_TCP1 PF00118.24 OAF99769.1 - 3.7e-166 553.6 0.6 4.2e-166 553.4 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 OAF99769.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Glyco_hydro_47 PF01532.20 OAF99770.1 - 1.1e-191 637.8 0.0 1.3e-191 637.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Polysacc_lyase PF14099.6 OAF99771.1 - 0.0043 16.9 0.8 0.013 15.4 0.8 1.7 1 1 0 1 1 1 1 Polysaccharide lyase Laminin_G_3 PF13385.6 OAF99771.1 - 0.0093 16.1 0.1 0.022 14.9 0.0 1.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Prim-Pol PF09250.11 OAF99771.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Sugar_tr PF00083.24 OAF99773.1 - 1e-77 262.0 20.5 1.2e-77 261.7 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAF99773.1 - 7.7e-23 81.0 31.1 2.4e-20 72.8 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 OAF99773.1 - 0.22 11.8 2.4 0.49 10.6 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Gpi1 PF05024.15 OAF99774.1 - 3e-76 255.7 7.0 5.1e-76 254.9 7.0 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) zf-CCCH PF00642.24 OAF99776.1 - 5e-05 23.1 2.7 8.2e-05 22.4 2.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAF99776.1 - 0.0001 22.0 5.6 0.00018 21.2 5.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAF99776.1 - 0.00014 21.8 8.9 0.00024 21.0 8.9 1.4 1 0 0 1 1 1 1 Zinc finger domain Nucleoporin_FG PF13634.6 OAF99776.1 - 0.0089 16.9 144.4 30 5.6 30.0 6.8 2 1 4 6 6 6 1 Nucleoporin FG repeat region K_oxygenase PF13434.6 OAF99777.1 - 4.1e-19 68.9 0.2 5.9e-14 52.0 0.1 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAF99777.1 - 5.2e-16 58.8 0.0 2.3e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAF99777.1 - 1.4e-10 40.9 0.0 3.9e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAF99777.1 - 2.9e-09 35.9 0.0 7.1e-07 28.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAF99777.1 - 6.7e-06 26.2 0.0 3.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAF99777.1 - 2.6e-05 24.3 0.4 0.1 12.6 0.1 2.9 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 OAF99777.1 - 7.8e-05 22.4 0.4 1.9 8.0 0.1 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAF99777.1 - 0.00016 21.0 0.0 0.00073 18.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 OAF99777.1 - 0.00059 19.2 0.2 0.24 10.6 0.0 2.8 2 1 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAF99777.1 - 0.0096 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAF99777.1 - 0.011 14.8 0.2 0.036 13.1 0.1 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OAF99777.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAF99777.1 - 0.036 14.6 0.1 0.72 10.5 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAF99777.1 - 0.045 12.8 0.4 3.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Mqo PF06039.15 OAF99777.1 - 0.049 12.2 0.0 0.2 10.2 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 OAF99777.1 - 0.19 10.4 1.4 8.2 5.0 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 OAF99777.1 - 0.6 8.9 2.7 1 8.1 0.1 2.6 3 1 0 3 3 3 0 Tryptophan halogenase DUF155 PF02582.14 OAF99778.1 - 1e-45 156.0 0.0 1.5e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.12 OAF99778.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Rhomboid PF01694.22 OAF99779.1 - 3.1e-11 43.5 6.9 3.1e-11 43.5 6.9 1.4 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.14 OAF99780.1 - 7.6e-169 562.9 0.4 1e-168 562.5 0.4 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Ribosomal_60s PF00428.19 OAF99780.1 - 0.04 14.5 1.0 0.098 13.3 1.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PCI PF01399.27 OAF99781.1 - 1.5e-08 35.1 0.0 4.3e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 OAF99781.1 - 8.1e-06 25.3 0.6 1.9e-05 24.2 0.3 1.8 2 0 0 2 2 2 1 Rpn9 C-terminal helix Glyco_transf_20 PF00982.21 OAF99781.1 - 0.0019 17.0 0.1 0.003 16.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 ANAPC5 PF12862.7 OAF99781.1 - 0.01 15.9 5.2 0.012 15.6 1.4 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Epimerase PF01370.21 OAF99782.1 - 3e-14 53.1 0.0 5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAF99782.1 - 2.4e-12 47.1 0.0 3.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAF99782.1 - 7.4e-12 45.3 0.0 9.7e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OAF99782.1 - 2e-11 43.5 0.0 3.4e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAF99782.1 - 5.4e-08 32.6 0.1 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAF99782.1 - 1.9e-07 30.5 0.0 6.3e-06 25.5 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAF99782.1 - 2e-05 23.9 0.4 0.0071 15.6 0.4 2.8 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.25 OAF99782.1 - 0.00017 21.1 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAF99782.1 - 0.00078 19.4 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 KR domain Polysacc_synt_2 PF02719.15 OAF99782.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 OAF99782.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2505 PF10698.9 OAF99782.1 - 0.039 14.1 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) RXLR PF16810.5 OAF99782.1 - 0.098 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Glyco_hydro_18 PF00704.28 OAF99784.1 - 7.7e-91 305.1 1.8 8.8e-91 304.9 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Bact_lectin PF18483.1 OAF99784.1 - 0.0086 16.1 0.0 1.1 9.3 0.0 2.8 2 1 0 2 2 2 1 Bacterial lectin DnaJ PF00226.31 OAF99785.1 - 1.4e-07 31.5 1.0 2.8e-07 30.6 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain YqcI_YcgG PF08892.11 OAF99786.1 - 0.041 13.7 0.2 2.2 8.1 0.0 2.4 2 1 0 2 2 2 0 YqcI/YcgG family DNA_pol_A_exo1 PF01612.20 OAF99787.1 - 8e-07 28.9 0.0 2.7e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease GST_N_3 PF13417.6 OAF99788.1 - 1.3e-10 41.5 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAF99788.1 - 1.2e-09 38.3 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAF99788.1 - 4.8e-08 33.2 0.0 7.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAF99788.1 - 1.3e-07 31.7 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAF99788.1 - 6.5e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAF99788.1 - 0.0032 17.4 0.2 0.0082 16.2 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAF99788.1 - 0.042 14.6 0.0 0.072 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF4293 PF14126.6 OAF99789.1 - 1e-05 25.8 1.7 3.6e-05 24.1 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) Cation_efflux PF01545.21 OAF99789.1 - 0.0002 21.2 1.5 0.0013 18.5 0.4 2.1 2 0 0 2 2 2 1 Cation efflux family MgtE PF01769.16 OAF99789.1 - 0.00095 19.5 0.9 0.0037 17.6 0.4 2.1 2 0 0 2 2 2 1 Divalent cation transporter DUF4064 PF13273.6 OAF99789.1 - 0.0098 16.2 3.6 0.044 14.1 0.4 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) ASFV_J13L PF05568.11 OAF99789.1 - 0.094 12.5 0.4 0.094 12.5 0.4 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF4231 PF14015.6 OAF99789.1 - 0.1 13.0 5.0 0.12 12.8 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 OAF99789.1 - 0.58 8.9 5.5 1.9 7.2 0.0 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Pox_EPC_I2-L1 PF12575.8 OAF99789.1 - 1.3 9.3 5.8 0.43 10.8 0.7 2.6 2 1 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF4212 PF13937.6 OAF99789.1 - 1.7 9.1 7.9 1.7 9.1 1.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4212) ApoO PF09769.9 OAF99790.1 - 4e-38 130.3 0.1 7e-38 129.5 0.1 1.4 1 0 0 1 1 1 1 Apolipoprotein O DUF1304 PF06993.12 OAF99790.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Peptidase_M3 PF01432.20 OAF99791.1 - 4.9e-128 428.3 0.0 6.7e-128 427.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 OAF99791.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M91 PF14891.6 OAF99791.1 - 0.07 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Effector protein Imm49 PF15575.6 OAF99791.1 - 0.34 10.6 4.5 0.13 12.0 0.8 2.2 2 0 0 2 2 2 0 Immunity protein 49 DUF3328 PF11807.8 OAF99792.1 - 2.2e-41 142.0 0.5 2.8e-41 141.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAF99794.1 - 5.2e-42 144.1 0.0 7.2e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Kinesin PF00225.23 OAF99795.1 - 3.6e-57 193.8 0.0 9.1e-57 192.5 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAF99795.1 - 1.3e-10 41.4 0.0 2.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 OAF99795.1 - 0.16 12.2 0.1 0.48 10.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF3328 PF11807.8 OAF99797.1 - 6.8e-22 78.3 5.2 4.3e-21 75.7 5.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4207 PF13904.6 OAF99798.1 - 0.037 13.7 2.0 0.061 13.0 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) TPR_19 PF14559.6 OAF99800.1 - 8.8e-11 42.2 1.6 0.068 13.7 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAF99800.1 - 6.3e-10 38.4 15.0 0.0044 17.0 0.4 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAF99800.1 - 1e-09 37.8 9.3 0.0067 16.2 0.4 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAF99800.1 - 6.3e-09 35.9 5.6 3 8.9 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAF99800.1 - 7.7e-08 32.0 9.1 0.014 15.6 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAF99800.1 - 2.7e-07 30.1 10.1 0.0067 16.1 0.2 5.1 6 0 0 6 6 6 2 TPR repeat TPR_16 PF13432.6 OAF99800.1 - 2.1e-06 28.3 1.0 1.1 10.0 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAF99800.1 - 2.9e-06 26.9 6.2 0.29 11.2 0.0 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAF99800.1 - 6.9e-05 23.1 12.0 0.073 13.4 0.3 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAF99800.1 - 0.00035 21.0 5.6 5.9 7.7 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAF99800.1 - 0.017 15.2 1.6 14 5.9 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAF99800.1 - 0.061 13.6 7.8 4.7 7.5 0.4 4.9 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 OAF99800.1 - 0.072 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 OAF99800.1 - 0.093 12.6 4.7 4.2 7.4 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAF99800.1 - 0.11 12.9 0.4 2.3 8.8 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAF99800.1 - 0.28 11.3 1.7 15 5.8 0.1 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 OAF99800.1 - 0.61 10.1 2.5 14 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SYS1 PF09801.9 OAF99801.1 - 1.6e-59 200.2 10.9 1.8e-59 200.1 10.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.17 OAF99802.1 - 1.4e-23 82.9 5.3 1.7e-23 82.6 5.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 OAF99802.1 - 0.072 13.4 2.3 0.49 10.7 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF2263 PF10021.9 OAF99804.1 - 6.1e-14 52.6 0.0 9.6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Mito_carr PF00153.27 OAF99805.1 - 1.5e-63 210.7 0.6 2.1e-22 78.8 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2 PF00152.20 OAF99805.1 - 1.6e-61 208.1 0.0 5.2e-61 206.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAF99805.1 - 5.1e-08 32.8 0.0 9.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Serine_protease PF18405.1 OAF99805.1 - 0.032 13.4 0.1 0.11 11.7 0.1 2.0 1 1 0 1 1 1 0 Gammaproteobacterial serine protease AAA PF00004.29 OAF99806.1 - 2.5e-37 128.2 0.0 4.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAF99806.1 - 7.7e-09 35.2 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 OAF99806.1 - 9e-09 35.2 0.0 4.1e-07 29.9 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 OAF99806.1 - 2.3e-05 24.7 0.1 0.001 19.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAF99806.1 - 2.8e-05 23.9 0.0 5.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAF99806.1 - 7.4e-05 23.2 2.9 0.0059 17.0 0.1 3.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAF99806.1 - 0.00031 20.8 0.0 0.0011 18.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAF99806.1 - 0.00053 19.3 0.1 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 OAF99806.1 - 0.0011 19.2 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAF99806.1 - 0.0012 18.7 0.0 0.0031 17.3 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OAF99806.1 - 0.0041 16.5 0.1 0.0099 15.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAF99806.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OAF99806.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAF99806.1 - 0.022 14.3 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAF99806.1 - 0.031 14.4 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAF99806.1 - 0.066 13.8 0.0 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAF99806.1 - 0.07 12.9 0.0 0.27 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAF99806.1 - 0.11 12.8 0.4 0.56 10.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAF99806.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAF99806.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OAF99806.1 - 0.2 11.1 0.0 6.3 6.1 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 OAF99806.1 - 0.21 11.3 0.1 0.47 10.1 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain PhoH PF02562.16 OAF99806.1 - 0.23 10.9 0.0 0.43 10.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein R3H PF01424.22 OAF99807.1 - 5.4e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 OAF99807.1 - 1.8e-08 34.1 0.8 3.7e-08 33.1 0.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAF99807.1 - 0.038 14.1 0.4 0.038 14.1 0.4 2.2 2 0 0 2 2 2 0 G-patch domain Chromo PF00385.24 OAF99807.1 - 0.18 11.7 0.2 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Vg_Tdu PF07545.14 OAF99807.1 - 0.31 10.8 1.1 0.67 9.8 1.1 1.5 1 0 0 1 1 1 0 Vestigial/Tondu family Peptidase_C54 PF03416.19 OAF99808.1 - 1.3e-95 320.0 0.0 1.7e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.24 OAF99809.1 - 4.8e-23 81.9 0.4 6e-23 81.6 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAF99809.1 - 7.4e-05 23.0 1.0 0.00011 22.5 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAF99809.1 - 0.00027 21.4 0.0 0.00045 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 OAF99809.1 - 0.029 15.3 0.4 0.041 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 OAF99809.1 - 0.064 12.9 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 OAF99810.1 - 2.8e-21 74.9 2.6 5e-21 74.1 2.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAF99810.1 - 6.9e-17 62.0 0.0 9.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAF99810.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 OAF99811.1 - 6.7e-09 35.7 1.0 8.9e-09 35.3 1.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 OAF99812.1 - 1.5e-78 263.5 0.1 2e-78 263.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAF99812.1 - 2.5e-19 68.9 3.3 5e-19 67.9 3.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAF99812.1 - 0.00015 21.5 0.4 0.24 11.2 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 OAF99812.1 - 0.00075 20.2 0.4 1.9 9.2 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 OAF99812.1 - 0.055 13.4 0.5 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Coilin_N PF15862.5 OAF99812.1 - 0.16 11.8 3.2 0.13 12.0 1.8 1.6 1 1 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 OAF99812.1 - 0.21 10.3 9.3 0.31 9.8 9.3 1.2 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 OAF99812.1 - 0.27 10.6 8.8 3.7 6.8 7.0 2.1 2 0 0 2 2 2 0 FAM76 protein GAGA_bind PF06217.12 OAF99812.1 - 0.78 10.0 7.4 1.1 9.5 7.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1387 PF07139.11 OAF99812.1 - 3.7 7.2 14.0 3.9 7.1 13.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) Apt1 PF10351.9 OAF99812.1 - 3.8 6.3 8.8 6.5 5.5 8.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 OAF99812.1 - 4.8 7.2 5.1 6.1 6.8 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 OAF99812.1 - 5.9 5.0 7.9 7.8 4.6 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RBD-FIP PF09457.10 OAF99814.1 - 0.032 14.1 0.0 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 FIP domain GDPD PF03009.17 OAF99816.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Adeno_terminal PF02459.15 OAF99821.1 - 0.012 14.0 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein EspB_PE PF18625.1 OAF99821.1 - 1.3 9.6 5.6 0.85 10.1 2.1 2.4 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain Tryp_inh PF17983.1 OAF99825.1 - 7.8 6.7 9.1 1.3 9.2 4.0 2.3 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 HTH_Tnp_Tc5 PF03221.16 OAF99826.1 - 8e-11 41.8 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Drf_GBD PF06371.13 OAF99826.1 - 0.011 15.3 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain HTH_23 PF13384.6 OAF99826.1 - 0.047 13.5 0.3 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_psq PF05225.16 OAF99826.1 - 0.071 12.9 0.1 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 helix-turn-helix, Psq domain CENP-B_N PF04218.13 OAF99826.1 - 0.088 12.5 0.2 1 9.1 0.0 2.1 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain SAPS PF04499.15 OAF99827.1 - 0.92 8.2 11.7 1.1 8.0 11.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PA26 PF04636.13 OAF99827.1 - 1.1 8.1 10.3 1.2 8.0 10.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 OAF99827.1 - 1.6 6.8 15.4 1.8 6.6 15.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gti1_Pac2 PF09729.9 OAF99827.1 - 4.1 7.5 16.5 1.2 9.2 13.5 1.5 1 1 1 2 2 2 0 Gti1/Pac2 family DUF4407 PF14362.6 OAF99827.1 - 7.3 5.8 13.9 8.8 5.6 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_11 PF13086.6 OAF99827.1 - 7.4 6.3 16.6 9.1 6.0 16.6 1.2 1 0 0 1 1 1 0 AAA domain Muted PF14942.6 OAF99827.1 - 8.3 6.7 25.6 0.76 10.1 19.1 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Fer2 PF00111.27 OAF99829.1 - 6.5e-06 26.0 3.6 1.1e-05 25.3 3.6 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1664 PF07889.12 OAF99834.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CRPV_capsid PF08762.10 OAF99841.1 - 0.03 14.0 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 CRPV capsid protein like PhoR PF11808.8 OAF99841.1 - 8 7.0 7.0 0.92 10.0 0.1 2.7 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR Toxin_11 PF07473.11 OAF99846.1 - 0.84 9.8 4.5 0.47 10.6 0.4 2.4 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species Peptidase_C48 PF02902.19 OAF99850.1 - 4e-06 26.8 0.0 9.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TACC_C PF05010.14 OAF99850.1 - 0.0059 16.4 4.0 0.017 14.9 4.0 1.7 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Glyco_hydro_18 PF00704.28 OAF99852.1 - 1.8e-08 34.5 0.0 1.9e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 YabA PF06156.13 OAF99854.1 - 0.13 12.9 0.2 0.18 12.5 0.2 1.1 1 0 0 1 1 1 0 Initiation control protein YabA DUF5560 PF17715.1 OAF99855.1 - 0.06 12.8 1.3 0.078 12.4 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5560) DIM PF08194.12 OAF99856.1 - 0.28 11.4 1.4 0.6 10.4 1.4 1.6 1 0 0 1 1 1 0 DIM protein PAF-AH_p_II PF03403.13 OAF99858.1 - 4.5e-21 74.8 0.0 3.5e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAF99858.1 - 1.1e-05 24.9 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAF99858.1 - 0.002 17.1 0.1 0.017 14.1 0.1 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 OAF99858.1 - 0.019 14.4 0.1 0.037 13.5 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAF99858.1 - 0.022 14.4 0.0 4.8 6.7 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAF99858.1 - 0.027 15.1 0.2 0.037 14.6 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OAF99858.1 - 0.11 11.5 0.0 5 6.0 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Lipase_3 PF01764.25 OAF99858.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF560 PF04575.13 OAF99859.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF560) BBE PF08031.12 OAF99860.1 - 2.5e-10 40.3 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Berberine and berberine like Flavokinase PF01687.17 OAF99861.1 - 4e-31 107.6 0.0 5.3e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.25 OAF99862.1 - 0.00082 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 OAF99862.1 - 0.0017 18.5 8.7 0.0027 17.8 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAF99863.1 - 2.5e-39 135.2 46.0 3.4e-39 134.8 38.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAF99863.1 - 4.4e-11 41.9 2.5 8.3e-11 41.0 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAF99863.1 - 1.3e-08 34.1 10.1 1.3e-08 34.1 10.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Bap31 PF05529.12 OAF99863.1 - 0.062 13.1 0.2 0.22 11.4 0.2 1.9 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region DUF1918 PF08940.11 OAF99863.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) GST_N PF02798.20 OAF99864.1 - 0.071 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glyco_hydro_16 PF00722.21 OAF99865.1 - 1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WGG PF10273.9 OAF99866.1 - 1.5e-29 102.5 0.3 2.4e-29 101.8 0.3 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 OAF99866.1 - 0.18 11.9 0.6 0.37 10.9 0.1 1.7 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Amidase PF01425.21 OAF99867.1 - 1.3e-99 334.3 0.0 1.6e-99 333.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Dioxygenase_C PF00775.21 OAF99868.1 - 1.7e-05 24.4 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.20 OAF99869.1 - 2.2e-30 106.6 0.4 4.1e-30 105.7 0.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M20 PF01546.28 OAF99870.1 - 5.1e-23 81.9 0.0 1.7e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 OAF99870.1 - 4e-11 43.3 0.9 0.06 14.2 0.0 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 OAF99870.1 - 6e-06 26.2 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.6 OAF99870.1 - 0.052 14.1 2.4 31 5.2 0.0 5.3 5 1 1 6 6 6 0 PQQ-like domain Med3 PF11593.8 OAF99871.1 - 0.19 10.9 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.17 OAF99872.1 - 0.68 9.9 8.2 1.2 9.1 8.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF572 PF04502.13 OAF99872.1 - 0.85 9.2 17.7 0.41 10.2 5.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Fungal_trans_2 PF11951.8 OAF99874.1 - 0.012 14.5 0.0 0.021 13.6 0.0 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain AA_permease_2 PF13520.6 OAF99876.1 - 0.017 14.0 2.2 0.058 12.2 2.4 1.7 1 1 0 1 1 1 0 Amino acid permease Peptidase_S9 PF00326.21 OAF99877.1 - 0.00016 21.2 0.0 0.00049 19.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 OAF99877.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 OAF99877.1 - 0.019 13.7 0.1 0.083 11.6 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 OAF99877.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 OAF99877.1 - 0.16 11.4 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Esterase PHB depolymerase PNP_UDP_1 PF01048.20 OAF99879.1 - 3.6e-39 134.4 0.0 4.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Amidase PF01425.21 OAF99880.1 - 2e-76 257.8 0.1 3.9e-75 253.5 0.1 2.0 1 1 0 1 1 1 1 Amidase NAD_binding_10 PF13460.6 OAF99881.1 - 1.3e-15 57.8 0.0 1.9e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAF99881.1 - 4.1e-12 46.1 0.0 6.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAF99881.1 - 1.8e-10 41.1 0.1 2.9e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAF99881.1 - 1.9e-06 27.5 0.1 5.4e-06 26.0 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAF99881.1 - 3.8e-06 27.4 0.1 6.9e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAF99881.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 OAF99881.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.22 OAF99881.1 - 0.0016 19.2 0.3 0.0028 18.5 0.3 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.12 OAF99881.1 - 0.0024 17.1 0.0 0.0058 15.8 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 OAF99881.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAF99881.1 - 0.039 14.2 0.1 0.064 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 OAF99881.1 - 0.04 14.0 0.1 0.062 13.4 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 OAF99881.1 - 0.095 12.1 0.1 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAF99881.1 - 0.13 11.4 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SET PF00856.28 OAF99883.1 - 0.068 13.6 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 SET domain MFS_1 PF07690.16 OAF99884.1 - 1.1e-41 143.0 32.6 1.1e-41 143.0 32.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAF99884.1 - 6.3e-13 48.0 10.6 9.1e-13 47.5 10.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAF99884.1 - 8.2e-12 44.7 11.7 8.2e-12 44.7 11.7 3.5 2 1 1 3 3 3 3 Sugar (and other) transporter Pox_A14 PF05767.12 OAF99884.1 - 0.016 15.3 1.8 0.049 13.8 0.1 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 MASE3 PF17159.4 OAF99884.1 - 2.3 7.8 10.1 0.13 11.9 2.9 2.4 1 1 1 2 2 2 0 Membrane-associated sensor domain Oxidored_FMN PF00724.20 OAF99885.1 - 4.1e-62 210.4 0.0 5.1e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HSP70 PF00012.20 OAF99886.1 - 1e-259 862.8 17.4 1.2e-259 862.6 17.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAF99886.1 - 4.1e-19 68.6 1.3 3.3e-18 65.6 0.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 OAF99886.1 - 0.0087 15.4 1.6 0.0087 15.4 1.6 1.7 2 0 0 2 2 2 1 Radial spoke protein 3 FGGY_C PF02782.16 OAF99886.1 - 0.021 14.6 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OAF99886.1 - 0.062 13.7 9.4 5.5 7.5 0.6 3.7 3 2 0 3 3 3 0 Cell division protein FtsA MSA-2c PF12238.8 OAF99887.1 - 6.5 6.7 5.6 10 6.0 5.6 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c KCH PF16944.5 OAF99889.1 - 1.1e-94 317.0 11.9 1.3e-94 316.7 11.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel TrbC PF04956.13 OAF99889.1 - 3.6 7.9 7.9 20 5.5 0.0 2.9 2 1 0 3 3 3 0 TrbC/VIRB2 family F-box PF00646.33 OAF99892.1 - 3.1e-05 23.7 0.0 0.0031 17.4 0.0 3.5 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 OAF99892.1 - 0.081 12.8 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 F-box-like SelR PF01641.18 OAF99893.1 - 9.3e-47 158.1 0.0 1.1e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 OAF99893.1 - 0.035 14.1 1.8 1.8 8.6 0.1 2.3 2 1 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 OAF99893.1 - 0.14 11.7 1.3 1 9.0 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding MFS_1 PF07690.16 OAF99894.1 - 4.7e-18 65.2 45.5 1.1e-17 64.0 14.2 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OAF99894.1 - 0.041 12.3 0.2 0.066 11.6 0.2 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector HsbA PF12296.8 OAF99895.1 - 2.3e-20 73.2 11.0 3.3e-20 72.7 11.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 OAF99895.1 - 0.022 14.8 4.0 0.47 10.5 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_7 PF03492.15 OAF99896.1 - 1.2e-24 87.2 0.0 2.1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Mito_carr PF00153.27 OAF99897.1 - 1.1e-52 175.9 4.8 1.4e-18 66.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAF99897.1 - 0.0021 17.3 1.3 0.0041 16.3 0.7 1.9 1 1 0 1 1 1 1 Gammaproteobacterial serine protease COX7C PF02935.16 OAF99897.1 - 0.13 12.5 0.8 1 9.7 0.3 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc zf-Nse PF11789.8 OAF99898.1 - 9e-23 79.9 0.1 1.5e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OAF99898.1 - 0.0015 18.6 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger DUF4164 PF13747.6 OAF99898.1 - 0.057 13.7 8.4 0.22 11.8 0.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) zf-C3HC4_2 PF13923.6 OAF99898.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ApoC-I PF04691.12 OAF99898.1 - 0.082 12.8 0.2 0.082 12.8 0.2 1.9 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) zf-MIZ PF02891.20 OAF99898.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Leu_zip PF15294.6 OAF99898.1 - 0.24 10.9 4.9 0.18 11.3 1.5 2.0 2 0 0 2 2 2 0 Leucine zipper CAF1 PF04857.20 OAF99898.1 - 1.3 8.1 4.6 0.32 10.1 0.6 1.7 1 1 0 2 2 2 0 CAF1 family ribonuclease PHY PF00360.20 OAF99900.1 - 7.4e-30 103.6 0.0 1.6e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 OAF99900.1 - 9.2e-18 64.8 0.1 2.5e-17 63.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAF99900.1 - 1.8e-16 60.3 0.0 6.4e-16 58.5 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 OAF99900.1 - 6.6e-14 52.7 0.0 2e-12 47.9 0.0 2.5 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 OAF99900.1 - 1e-12 47.9 0.9 4.6e-12 45.8 0.9 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 OAF99900.1 - 5.1e-09 36.8 0.0 2.5e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 OAF99900.1 - 0.032 14.2 0.1 0.079 12.9 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain VGLL4 PF15245.6 OAF99900.1 - 0.087 12.9 2.5 0.2 11.7 2.5 1.5 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Flavoprotein PF02441.19 OAF99901.1 - 3.6e-15 56.0 0.0 6.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 OAF99901.1 - 0.0047 17.5 0.0 1.8 9.2 0.0 3.6 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.14 OAF99901.1 - 9.5 6.1 9.6 16 5.4 0.1 4.4 6 1 1 7 7 7 0 hAT family C-terminal dimerisation region KH_1 PF00013.29 OAF99902.1 - 4e-94 308.4 26.4 2.5e-13 49.6 0.1 13.4 13 1 0 13 13 13 10 KH domain SLS PF14611.6 OAF99902.1 - 1.9e-13 50.8 1.1 0.0022 17.8 0.0 7.5 4 2 2 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 OAF99902.1 - 5.2e-12 45.4 21.0 0.0044 16.8 0.3 8.2 7 2 1 9 9 9 4 KH domain KH_4 PF13083.6 OAF99902.1 - 0.0028 17.5 5.0 4.7 7.1 0.3 5.7 7 0 0 7 7 7 1 KH domain Glyoxalase_4 PF13669.6 OAF99903.1 - 3.1e-07 30.6 0.0 1.4e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_23 PF13489.6 OAF99904.1 - 1.4e-24 86.8 0.0 2.5e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAF99904.1 - 2.8e-09 37.6 0.0 7.8e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAF99904.1 - 9.6e-08 32.7 0.0 6.7e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAF99904.1 - 3.7e-07 30.7 0.0 7.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAF99904.1 - 1e-06 28.6 0.0 1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAF99904.1 - 0.0092 15.3 0.0 0.12 11.7 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OAF99904.1 - 0.018 14.5 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAF99904.1 - 0.042 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 OAF99904.1 - 0.084 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 OAF99904.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 OAF99904.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase p450 PF00067.22 OAF99905.1 - 7.4e-49 166.7 0.0 9.4e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP-synt_J PF04911.12 OAF99905.1 - 0.062 12.9 0.7 0.13 11.9 0.7 1.5 1 0 0 1 1 1 0 ATP synthase j chain MFS_1 PF07690.16 OAF99906.1 - 5.3e-29 101.3 57.2 5.8e-22 78.1 34.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M28 PF04389.17 OAF99908.1 - 5e-22 78.6 0.0 8.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 OAF99908.1 - 1.4e-21 76.8 0.0 3e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 OAF99908.1 - 6.5e-09 35.7 0.2 2e-08 34.1 0.2 1.8 1 0 0 1 1 1 1 PA domain Peptidase_S58 PF03576.14 OAF99909.1 - 1.1e-111 373.2 0.1 1.3e-111 372.9 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 ABC_membrane PF00664.23 OAF99910.1 - 1.2e-96 323.6 40.9 2.1e-49 168.6 17.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAF99910.1 - 1.9e-67 226.0 0.1 1.8e-32 112.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OAF99910.1 - 6.3e-14 51.9 7.2 6.9e-05 22.4 2.6 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAF99910.1 - 4.7e-07 30.4 1.5 0.013 15.9 0.4 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAF99910.1 - 4.7e-07 29.4 5.2 0.0062 16.2 0.2 3.2 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAF99910.1 - 1.1e-06 29.0 2.1 0.015 15.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAF99910.1 - 1.8e-06 28.0 0.1 0.043 13.6 0.0 3.3 3 1 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAF99910.1 - 4.4e-06 26.7 0.0 0.068 13.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OAF99910.1 - 4.7e-06 26.6 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 OAF99910.1 - 1.9e-05 24.5 1.5 0.057 13.1 0.1 3.6 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 OAF99910.1 - 2e-05 23.6 0.3 0.088 11.6 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 OAF99910.1 - 2.5e-05 23.7 0.1 0.034 13.4 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin G-alpha PF00503.20 OAF99910.1 - 4.1e-05 22.9 0.0 0.07 12.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.6 OAF99910.1 - 5.8e-05 23.6 0.0 0.12 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAF99910.1 - 0.00025 21.2 0.0 0.34 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 OAF99910.1 - 0.00041 20.5 0.6 0.59 10.2 0.0 3.0 2 1 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 OAF99910.1 - 0.00049 20.7 0.0 0.41 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAF99910.1 - 0.00093 19.2 0.1 2.1 8.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 OAF99910.1 - 0.001 19.5 2.8 2.7 8.4 0.2 3.7 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAF99910.1 - 0.0016 18.7 0.0 1.3 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OAF99910.1 - 0.0021 18.2 3.2 2 8.7 0.2 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Ploopntkinase3 PF18751.1 OAF99910.1 - 0.0038 17.2 0.2 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 OAF99910.1 - 0.004 16.4 0.3 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 OAF99910.1 - 0.0059 16.5 0.1 2.9 7.8 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase MMR_HSR1 PF01926.23 OAF99910.1 - 0.0069 16.5 0.0 6.3 6.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAF99910.1 - 0.0073 16.1 0.1 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 OAF99910.1 - 0.0074 16.0 0.0 0.47 10.2 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 OAF99910.1 - 0.0082 15.7 0.1 4.2 6.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAF99910.1 - 0.0083 16.1 0.0 3.2 7.6 0.0 3.2 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 OAF99910.1 - 0.02 14.4 0.0 8.6 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 OAF99910.1 - 0.043 13.6 1.8 10 5.8 0.0 3.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase DUF2567 PF10821.8 OAF99910.1 - 0.047 13.8 0.9 0.16 12.0 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) AAA_17 PF13207.6 OAF99910.1 - 0.048 14.1 0.5 4 7.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAF99910.1 - 0.052 12.9 0.4 5 6.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 OAF99910.1 - 0.16 12.4 0.0 8.6 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAF99910.1 - 0.18 11.7 0.4 12 5.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Grg1 PF11034.8 OAF99911.1 - 1.6e-09 37.9 7.3 2e-09 37.5 7.3 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 FMO-like PF00743.19 OAF99913.1 - 1e-29 103.4 0.0 1.1e-17 63.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAF99913.1 - 8.8e-11 41.6 0.3 4e-07 29.6 0.0 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAF99913.1 - 2.7e-07 30.1 0.0 0.028 13.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAF99913.1 - 5.8e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAF99913.1 - 1.8e-05 24.8 0.1 0.0032 17.5 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAF99913.1 - 3.1e-05 23.7 0.8 0.0012 18.5 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAF99913.1 - 0.00015 21.1 0.3 0.1 11.7 0.0 3.2 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAF99913.1 - 0.063 12.0 0.5 0.093 11.4 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Glu_dehyd_C PF16912.5 OAF99913.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Semialdhyde_dh PF01118.24 OAF99913.1 - 0.1 13.1 0.0 0.46 10.9 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Thi4 PF01946.17 OAF99913.1 - 0.25 10.6 0.1 0.5 9.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAF99913.1 - 0.38 11.4 0.8 0.81 10.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 OAF99914.1 - 1.6e-26 92.2 0.2 2e-26 91.9 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAF99914.1 - 3.8e-09 36.8 0.1 8.5e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 OAF99914.1 - 1e-07 31.6 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAF99914.1 - 4.9e-07 29.7 0.2 1.2e-06 28.4 0.2 1.5 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OAF99914.1 - 6.9e-07 29.7 0.3 2.9e-06 27.7 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 OAF99914.1 - 1.1e-06 28.4 0.2 9.7e-06 25.4 0.2 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 OAF99914.1 - 1.1e-05 25.2 0.1 1.6e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OAF99914.1 - 1.9e-05 24.8 0.0 2.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Imm61 PF15598.6 OAF99914.1 - 0.0069 16.3 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 Immunity protein 61 TraF PF13728.6 OAF99914.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 OAF99914.1 - 0.027 14.7 0.3 0.07 13.4 0.3 1.7 1 1 0 1 1 1 0 Glutaredoxin DUF953 PF06110.11 OAF99914.1 - 0.045 13.4 0.3 0.094 12.3 0.2 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 OAF99914.1 - 0.056 13.5 0.3 0.13 12.3 0.1 1.7 1 1 1 2 2 2 0 Thioredoxin domain RNA_pol_Rpb4 PF03874.16 OAF99916.1 - 3e-18 66.3 0.1 4.5e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Nop PF01798.18 OAF99917.1 - 4.6e-79 265.1 0.1 4.6e-79 265.1 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAF99917.1 - 1e-18 67.5 3.3 1e-18 67.5 3.3 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Actin PF00022.19 OAF99918.1 - 4.4e-28 98.0 0.0 9.3e-18 64.0 0.0 2.7 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.13 OAF99918.1 - 0.087 11.6 0.0 9.4 4.9 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 OAF99919.1 - 2.2e-54 184.6 0.0 9.6e-49 166.0 0.0 2.5 2 1 0 2 2 2 2 Asparaginase Acetyltransf_7 PF13508.7 OAF99919.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAF99919.1 - 0.21 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.11 OAF99920.1 - 2.1e-13 50.9 8.5 7.6e-11 42.6 0.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Thyroglobulin_1 PF00086.18 OAF99921.1 - 0.059 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat Fungal_trans PF04082.18 OAF99922.1 - 2.1e-18 66.3 0.4 3.1e-18 65.8 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF99922.1 - 2.1e-08 34.1 10.2 2.1e-08 34.1 10.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 OAF99923.1 - 5.1e-90 302.3 38.0 6e-90 302.1 38.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4834 PF16118.5 OAF99924.1 - 0.041 14.8 0.8 0.1 13.5 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Colicin_V PF02674.16 OAF99924.1 - 0.08 12.9 4.8 0.11 12.5 4.3 1.4 1 1 0 1 1 1 0 Colicin V production protein GFO_IDH_MocA PF01408.22 OAF99925.1 - 0.071 13.9 0.0 0.079 13.8 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF327 PF03885.13 OAF99925.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Cellulase PF00150.18 OAF99926.1 - 3.4e-15 56.2 0.6 3.4e-15 56.2 0.6 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CTP_transf_like PF01467.26 OAF99927.1 - 2e-24 86.4 0.0 3.9e-24 85.5 0.0 1.5 2 0 0 2 2 2 1 Cytidylyltransferase-like HECT PF00632.25 OAF99928.1 - 3.3e-77 260.0 0.0 5e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 OAF99928.1 - 0.33 11.1 5.9 92 3.3 0.0 6.0 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat RRN3 PF05327.11 OAF99928.1 - 2.3 6.7 7.3 5.1 5.5 7.3 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 OAF99928.1 - 3.4 6.3 6.9 13 4.5 6.9 2.0 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Smr PF01713.21 OAF99929.1 - 0.0024 18.2 0.3 0.0061 16.9 0.3 1.7 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 OAF99929.1 - 0.01 16.2 3.9 0.022 15.1 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) SPC12 PF06645.13 OAF99932.1 - 0.047 13.8 0.2 0.093 12.8 0.2 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Herpes_IE68 PF02479.16 OAF99933.1 - 0.067 12.8 0.1 0.075 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus immediate early protein TCO89 PF10452.9 OAF99934.1 - 5.2e-06 25.7 1.1 0.00025 20.2 0.1 3.9 3 1 1 4 4 4 2 TORC1 subunit TCO89 ABC_tran PF00005.27 OAF99936.1 - 7.3e-44 149.6 0.3 9.1e-22 78.1 0.0 3.3 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 OAF99936.1 - 8.6e-20 71.7 4.2 0.00017 21.5 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAF99936.1 - 9.8e-12 44.8 0.6 0.095 12.1 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAF99936.1 - 8.3e-07 28.7 1.3 0.003 17.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 OAF99936.1 - 2.5e-06 27.4 6.2 1e-05 25.5 6.2 2.0 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 OAF99936.1 - 4.6e-06 26.5 0.9 0.16 11.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAF99936.1 - 3e-05 24.0 0.1 0.02 14.8 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAF99936.1 - 0.00043 20.7 7.1 0.14 12.5 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 OAF99936.1 - 0.0013 19.2 0.9 2.6 8.5 0.2 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAF99936.1 - 0.0016 18.4 2.4 0.91 9.4 0.0 3.5 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 OAF99936.1 - 0.0018 18.5 3.1 0.38 11.0 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 OAF99936.1 - 0.0023 18.5 14.8 0.052 14.0 4.6 3.7 3 1 0 3 3 3 2 AAA domain AAA_27 PF13514.6 OAF99936.1 - 0.0029 17.2 2.0 0.0064 16.1 0.0 2.5 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 OAF99936.1 - 0.0029 16.7 0.9 0.016 14.3 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein MeaB PF03308.16 OAF99936.1 - 0.0037 16.3 0.5 0.73 8.8 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 OAF99936.1 - 0.0047 16.4 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 OAF99936.1 - 0.0084 15.9 5.0 0.015 15.1 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 OAF99936.1 - 0.009 16.3 0.2 0.95 9.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAF99936.1 - 0.013 15.1 0.2 2.2 7.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 OAF99936.1 - 0.021 14.7 0.4 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 OAF99936.1 - 0.023 13.9 1.3 7 5.8 0.3 2.9 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 OAF99936.1 - 0.029 14.9 2.0 5.3 7.6 0.1 3.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAF99936.1 - 0.032 13.4 0.1 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 OAF99936.1 - 0.034 14.2 5.9 1.7 8.8 0.3 3.6 3 1 1 4 4 3 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAF99936.1 - 0.045 13.5 0.4 5.1 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OAF99936.1 - 0.084 12.5 0.9 3.5 7.2 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 OAF99936.1 - 0.11 12.5 0.2 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 OAF99936.1 - 0.12 12.3 0.2 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OAF99936.1 - 0.2 12.1 0.0 3.9 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 OAF99936.1 - 0.21 11.2 2.5 4.4 6.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 OAF99936.1 - 0.25 11.7 1.8 2.4 8.5 0.0 2.6 2 2 0 2 2 2 0 AAA domain DUF2149 PF09919.9 OAF99936.1 - 0.34 11.2 1.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) AAA_33 PF13671.6 OAF99936.1 - 0.36 11.0 5.4 5.7 7.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain FAM25 PF15825.5 OAF99936.1 - 8.6 6.8 6.1 21 5.5 6.1 1.6 1 0 0 1 1 1 0 FAM25 family zf-Di19 PF05605.12 OAF99937.1 - 0.033 14.5 0.0 0.088 13.1 0.0 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 OAF99937.1 - 0.12 13.2 0.2 0.49 11.4 0.2 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger RNA_pol_Rpc82 PF05645.13 OAF99937.1 - 0.89 9.3 4.7 1.8 8.2 0.8 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 DUF3659 PF12396.8 OAF99938.1 - 4.7e-06 26.4 0.8 0.0015 18.4 0.2 3.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3659) adh_short PF00106.25 OAF99939.1 - 1.1e-21 77.2 0.4 1.8e-21 76.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99939.1 - 5.7e-16 58.8 0.1 7.3e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAF99939.1 - 0.0013 18.3 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OAF99939.1 - 0.0046 16.9 0.6 0.0081 16.1 0.2 1.6 2 0 0 2 2 2 1 KR domain Methyltransf_4 PF02390.17 OAF99939.1 - 0.019 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TrkA_N PF02254.18 OAF99939.1 - 0.029 14.6 0.3 0.064 13.5 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.6 OAF99939.1 - 0.1 12.5 1.8 0.31 10.9 1.7 1.9 1 1 0 1 1 1 0 NAD(P)H-binding NB-ARC PF00931.22 OAF99941.1 - 3.4e-13 49.4 0.0 5.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain HET PF06985.11 OAF99941.1 - 1.2e-11 45.1 10.5 2.6e-09 37.6 1.8 3.6 3 1 1 4 4 4 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 OAF99941.1 - 4.1e-10 40.3 0.2 1.1e-09 38.9 0.2 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAF99941.1 - 1.7e-06 28.4 0.0 6.6e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAF99941.1 - 2.7e-05 24.1 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 OAF99941.1 - 0.00038 20.9 0.0 0.0042 17.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OAF99941.1 - 0.0049 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 OAF99941.1 - 0.016 15.1 0.0 0.042 13.7 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 OAF99941.1 - 0.027 14.5 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAF99941.1 - 0.027 14.0 0.0 0.069 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAF99941.1 - 0.084 13.4 0.0 0.25 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain TIR_2 PF13676.6 OAF99941.1 - 0.27 11.8 1.4 1 10.0 0.1 2.6 3 0 0 3 3 3 0 TIR domain ThrE PF06738.12 OAF99943.1 - 2.6e-68 230.0 15.5 7.5e-67 225.2 1.0 2.5 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAF99943.1 - 0.00012 22.2 3.2 0.00012 22.2 3.2 3.8 4 0 0 4 4 4 2 Threonine/Serine exporter, ThrE TMEM220 PF15071.6 OAF99943.1 - 0.46 11.3 1.6 0.91 10.3 0.2 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix FAD_binding_3 PF01494.19 OAF99945.1 - 5.5e-39 134.4 0.0 7.9e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAF99945.1 - 1.6e-05 24.3 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAF99945.1 - 0.00015 21.8 0.4 0.086 12.8 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAF99945.1 - 0.00055 20.4 0.0 0.31 11.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAF99945.1 - 0.00082 18.5 0.1 0.0025 16.9 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAF99945.1 - 0.00099 18.8 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAF99945.1 - 0.0033 16.7 0.1 0.006 15.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAF99945.1 - 0.015 15.6 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAF99945.1 - 0.02 13.6 0.0 0.087 11.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Myosin_N PF02736.19 OAF99945.1 - 2.7 7.9 5.2 5.3 7.0 1.8 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain p450 PF00067.22 OAF99946.1 - 5.9e-58 196.7 0.0 7.6e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAF99947.1 - 1.6e-27 96.4 0.0 2.8e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Tannase PF07519.11 OAF99948.1 - 1.6e-92 310.9 0.0 1.9e-92 310.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 OAF99948.1 - 0.0083 15.8 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Waikav_capsid_1 PF12264.8 OAF99948.1 - 0.15 11.6 0.0 0.82 9.1 0.0 1.9 2 0 0 2 2 2 0 Waikavirus capsid protein 1 BNR_2 PF13088.6 OAF99949.1 - 1.7e-05 24.3 0.4 0.0015 17.9 0.1 2.2 1 1 0 2 2 2 2 BNR repeat-like domain DUF5530 PF17670.1 OAF99949.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5530) Adeno_E3_14_5 PF04834.12 OAF99949.1 - 0.091 13.3 0.1 0.25 11.9 0.1 1.8 1 0 0 1 1 1 0 Early E3 14.5 kDa protein BNR_3 PF13859.6 OAF99949.1 - 0.19 11.0 1.4 2.7 7.2 0.1 2.6 1 1 0 2 2 2 0 BNR repeat-like domain BNR PF02012.20 OAF99949.1 - 0.49 10.6 3.3 19 5.8 0.5 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat NPC1_N PF16414.5 OAF99951.1 - 6.6e-83 278.0 8.7 1.4e-82 277.0 8.7 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 OAF99951.1 - 5.1e-74 249.8 3.7 1.8e-73 248.0 3.7 1.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OAF99951.1 - 4.2e-52 176.1 5.1 4.2e-52 176.1 5.1 3.3 2 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 OAF99951.1 - 0.00029 20.7 0.7 0.00068 19.6 0.7 1.5 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.15 OAF99951.1 - 0.00037 19.5 9.3 0.00037 19.5 9.3 2.6 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.19 OAF99951.1 - 0.00061 17.6 7.7 0.00061 17.6 7.7 1.5 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Hydrolase_4 PF12146.8 OAF99951.1 - 0.19 11.0 0.3 0.42 9.8 0.1 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 HEAT PF02985.22 OAF99952.1 - 3.8e-18 64.0 2.5 0.002 18.2 0.1 10.8 12 0 0 12 12 10 2 HEAT repeat HEAT_EZ PF13513.6 OAF99952.1 - 1.9e-17 63.4 16.3 9e-07 29.3 0.2 10.6 12 1 2 14 14 11 4 HEAT-like repeat HEAT_2 PF13646.6 OAF99952.1 - 2.1e-14 53.7 9.3 0.0034 17.7 0.1 9.0 6 4 2 8 8 8 3 HEAT repeats IBN_N PF03810.19 OAF99952.1 - 3.5e-12 46.1 1.1 5.5e-11 42.2 0.3 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 OAF99952.1 - 3.7e-10 39.5 0.9 2.2 8.5 0.0 6.8 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 OAF99952.1 - 1.1e-09 38.7 0.0 0.34 11.5 0.0 5.6 6 0 0 6 6 6 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAF99952.1 - 5.7e-08 31.8 0.0 0.0023 16.6 0.0 3.6 4 1 0 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.7 OAF99952.1 - 7.7e-07 29.3 0.5 0.72 9.9 0.0 4.9 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 OAF99952.1 - 6.4e-06 26.0 0.0 8.5 6.1 0.0 5.1 5 1 1 6 6 6 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 OAF99952.1 - 3.2e-05 23.3 0.6 0.15 11.2 0.0 3.9 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 OAF99952.1 - 0.0007 19.7 0.4 3.5 7.9 0.0 4.4 3 2 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 OAF99952.1 - 0.002 17.3 6.2 11 5.0 0.3 5.6 3 2 3 6 6 6 1 Interferon-related developmental regulator (IFRD) API5 PF05918.11 OAF99952.1 - 0.014 14.3 0.5 1.2 7.9 0.0 3.4 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) CLASP_N PF12348.8 OAF99952.1 - 0.048 13.2 0.0 3.4 7.1 0.0 3.4 3 1 1 4 4 4 0 CLASP N terminal Tti2 PF10521.9 OAF99952.1 - 0.058 12.9 0.0 1.4 8.4 0.0 2.8 2 0 0 2 2 2 0 Tti2 family RICTOR_V PF14668.6 OAF99952.1 - 0.071 13.4 0.0 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF2433 PF10360.9 OAF99953.1 - 3.1e-47 159.7 0.0 5.1e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 OAF99953.1 - 0.0033 18.0 0.0 0.0067 16.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAF99953.1 - 0.028 14.6 0.0 0.094 12.9 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TFIIA PF03153.13 OAF99953.1 - 1 9.3 8.2 1.6 8.6 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 OAF99953.1 - 6.6 6.0 18.8 11 5.3 18.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LAMTOR PF15454.6 OAF99957.1 - 1.3e-12 48.1 1.7 2.2e-12 47.4 0.5 1.8 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ABC_tran PF00005.27 OAF99959.1 - 3.8e-33 114.9 0.0 7.7e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAF99959.1 - 4.4e-23 82.3 7.3 8.1e-23 81.4 7.3 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OAF99959.1 - 0.00077 19.0 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAF99959.1 - 0.0038 17.1 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_10 PF12846.7 OAF99959.1 - 0.0046 15.9 0.2 0.0085 15.1 0.2 1.3 1 0 0 1 1 1 1 AAA-like domain MoeA_C PF03454.15 OAF99959.1 - 0.035 14.3 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) AAA_22 PF13401.6 OAF99959.1 - 0.037 14.3 0.1 0.16 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAF99959.1 - 0.064 13.0 0.5 0.51 10.1 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAF99959.1 - 0.1 13.0 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain UPF0242 PF06785.11 OAF99961.1 - 0.019 15.0 0.3 0.024 14.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus VTC PF09359.10 OAF99962.1 - 0.16 11.3 6.1 0.21 10.9 6.1 1.1 1 0 0 1 1 1 0 VTC domain DUF2514 PF10721.9 OAF99962.1 - 0.44 10.6 4.0 0.82 9.7 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) FapA PF03961.13 OAF99962.1 - 3.7 6.1 7.0 4.5 5.8 7.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADH_zinc_N PF00107.26 OAF99965.1 - 1.4e-18 67.1 0.1 2.1e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAF99965.1 - 1.9e-12 47.0 2.7 1.9e-12 47.0 2.7 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAF99965.1 - 1.7e-09 37.5 0.1 2.4e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAF99965.1 - 0.0001 23.4 0.1 0.00017 22.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAF99965.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAF99965.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAF99965.1 - 0.017 15.7 0.0 0.041 14.4 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAF99965.1 - 0.054 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Isochorismatase PF00857.20 OAF99966.1 - 3.6e-20 72.8 0.0 4.1e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family FA_desaturase PF00487.24 OAF99967.1 - 1e-30 107.4 21.2 2.4e-30 106.2 21.2 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAF99967.1 - 1.5e-10 41.0 0.0 2.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zn_clus PF00172.18 OAF99968.1 - 4.7e-05 23.4 9.5 0.0001 22.3 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCMA-Tall_bind PF09257.10 OAF99968.1 - 1.5 9.0 5.5 4.2 7.6 5.5 1.8 1 0 0 1 1 1 0 BCMA, TALL-1 binding Prefoldin_3 PF13758.6 OAF99969.1 - 6.3e-28 96.8 0.6 6.3e-28 96.8 0.6 2.6 3 0 0 3 3 3 1 Prefoldin subunit DUF3835 PF12927.7 OAF99969.1 - 3.7e-26 91.8 0.1 3.7e-26 91.8 0.1 5.7 5 2 1 7 7 7 1 Domain of unknown function (DUF3835) Prefoldin PF02996.17 OAF99969.1 - 0.002 18.0 3.4 0.011 15.6 3.4 2.2 1 1 0 1 1 1 1 Prefoldin subunit FAA_hydro_N_2 PF18288.1 OAF99969.1 - 0.041 14.3 0.8 0.18 12.3 0.2 2.5 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 SAT PF16073.5 OAF99969.1 - 0.056 13.2 2.0 0.099 12.4 2.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Nas2_N PF18265.1 OAF99969.1 - 0.41 10.6 5.9 0.51 10.3 0.3 3.2 3 0 0 3 3 3 0 Nas2 N_terminal domain DUF5340 PF17275.2 OAF99969.1 - 2.3 8.4 6.3 2.1 8.5 0.5 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5340) DUF4164 PF13747.6 OAF99969.1 - 7.1 7.0 11.0 8.1 6.8 0.7 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) MAT1 PF06391.13 OAF99970.1 - 2.1e-37 128.9 4.0 2.7e-37 128.6 4.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 OAF99970.1 - 8.4e-31 105.6 9.4 1.4e-30 104.9 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAF99970.1 - 0.0012 18.7 6.0 0.0037 17.1 6.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAF99970.1 - 0.0053 17.1 7.8 0.0089 16.3 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAF99970.1 - 0.0066 16.3 7.3 0.035 14.0 7.8 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAF99970.1 - 0.01 15.8 6.3 0.056 13.4 2.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 OAF99970.1 - 0.033 14.0 6.4 0.14 11.9 2.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAF99970.1 - 0.17 11.5 2.8 0.32 10.7 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3797 PF12677.7 OAF99970.1 - 0.34 10.8 2.4 0.69 9.9 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 OAF99970.1 - 2.6 8.1 7.9 5.1 7.2 7.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 OAF99970.1 - 9.1 6.2 9.3 1.8e+02 2.1 0.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TMEM171 PF15471.6 OAF99971.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Atx10homo_assoc PF09759.9 OAF99972.1 - 3.5e-30 103.9 3.2 1.4e-27 95.6 0.1 3.4 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HMG_box PF00505.19 OAF99972.1 - 2.9e-05 24.4 0.3 9.1e-05 22.8 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAF99972.1 - 3.7e-05 24.2 0.5 0.00015 22.3 0.5 2.0 1 0 0 1 1 1 1 HMG-box domain DUF853 PF05872.12 OAF99972.1 - 0.12 11.0 5.8 0.2 10.2 5.8 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AATF-Che1 PF13339.6 OAF99972.1 - 0.16 12.6 3.6 34 5.1 3.9 2.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DivIC PF04977.15 OAF99972.1 - 0.17 11.7 4.0 0.51 10.1 4.0 1.9 1 0 0 1 1 1 0 Septum formation initiator COG5 PF10392.9 OAF99972.1 - 0.19 11.9 2.1 0.49 10.6 2.1 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2205 PF10224.9 OAF99972.1 - 0.34 10.9 5.1 1 9.4 1.4 2.6 2 0 0 2 2 2 0 Short coiled-coil protein DUF4094 PF13334.6 OAF99972.1 - 0.6 10.6 3.3 1.4 9.4 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) GatB_Yqey PF02637.18 OAF99972.1 - 0.72 9.7 9.2 4.3 7.2 0.1 2.9 3 0 0 3 3 3 0 GatB domain Glycohydro_20b2 PF14845.6 OAF99972.1 - 0.76 10.4 2.5 2.6 8.7 2.4 1.9 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like MRPL52 PF18699.1 OAF99972.1 - 1.3 9.2 5.5 29 4.9 4.3 2.8 2 0 0 2 2 2 0 Mitoribosomal protein mL52 TolA_bind_tri PF16331.5 OAF99972.1 - 3.3 7.8 8.4 0.47 10.6 4.0 1.8 2 0 0 2 2 1 0 TolA binding protein trimerisation LPP PF04728.13 OAF99972.1 - 3.7 8.0 6.5 3.3 8.2 2.2 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Peptidase_S28 PF05577.12 OAF99973.1 - 3.2e-44 151.4 0.0 6.6e-44 150.4 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 CPSase_L_D3 PF02787.19 OAF99974.1 - 0.021 15.2 0.5 0.034 14.5 0.1 1.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Lactonase PF10282.9 OAF99975.1 - 6.7e-78 262.3 0.0 8.7e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Pec_lyase_C PF00544.19 OAF99976.1 - 1.6e-12 47.4 8.6 5.8e-11 42.4 8.6 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAF99976.1 - 0.0013 18.6 15.1 0.0084 16.0 3.1 2.5 1 1 1 2 2 2 2 Right handed beta helix region fn3_3 PF14686.6 OAF99976.1 - 0.12 12.1 1.8 3.2 7.6 0.6 2.9 1 1 0 2 2 2 0 Polysaccharide lyase family 4, domain II MFS_1 PF07690.16 OAF99977.1 - 2.9e-32 112.0 47.4 2.9e-32 112.0 47.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily COesterase PF00135.28 OAF99981.1 - 2.1e-80 271.1 0.0 3.1e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAF99981.1 - 7.3e-05 22.7 1.1 0.00073 19.4 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold VirB8 PF04335.13 OAF99982.1 - 0.16 11.8 0.2 0.94 9.3 0.1 2.1 2 0 0 2 2 2 0 VirB8 protein adh_short PF00106.25 OAF99983.1 - 7.5e-36 123.4 0.0 1.2e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAF99983.1 - 4.4e-25 88.6 0.0 5.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 OAF99983.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 OAF99983.1 - 0.0013 18.2 0.0 0.0018 17.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAF99983.1 - 0.0019 18.2 0.9 0.032 14.1 1.0 2.6 2 1 0 2 2 2 1 KR domain TrkA_N PF02254.18 OAF99983.1 - 0.0027 18.0 0.3 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.18 OAF99983.1 - 0.004 17.1 0.1 0.0085 16.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAF99983.1 - 0.013 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_11 PF08241.12 OAF99983.1 - 0.021 15.4 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 OAF99983.1 - 0.065 12.5 0.4 0.31 10.3 0.1 2.1 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 OAF99983.1 - 0.099 13.4 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_3 PF07859.13 OAF99984.1 - 9.7e-43 146.5 0.0 6.4e-33 114.4 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAF99984.1 - 6.1e-12 45.1 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 OAF99984.1 - 3.7e-05 22.8 0.0 8.1e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 OAF99984.1 - 0.025 13.8 0.0 0.067 12.5 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF908 PF06012.12 OAF99984.1 - 1.4 8.3 4.5 2.9 7.2 4.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TRAUB PF08164.12 OAF99985.1 - 1.6e-28 99.0 0.1 1.6e-28 99.0 0.1 2.8 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 OAF99985.1 - 3.2e-23 82.9 2.5 3.2e-23 82.9 2.5 2.6 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Nop14 PF04147.12 OAF99985.1 - 0.011 13.9 0.3 0.011 13.9 0.3 2.2 2 0 0 2 2 2 0 Nop14-like family Merozoite_SPAM PF07133.11 OAF99985.1 - 1.2 9.1 22.9 0.15 12.1 18.0 1.9 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) ParA PF10609.9 OAF99986.1 - 9.2e-91 303.7 0.0 1.1e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAF99986.1 - 1.7e-11 44.2 0.0 4e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAF99986.1 - 4.9e-11 42.9 0.2 4.1e-08 33.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 OAF99986.1 - 5.1e-06 26.0 0.0 7.3e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 OAF99986.1 - 0.00033 19.9 0.2 0.0037 16.5 0.2 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 OAF99986.1 - 0.0027 17.6 0.1 0.75 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAF99986.1 - 0.0028 17.3 0.1 0.008 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 OAF99986.1 - 0.033 13.7 0.2 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 OAF99986.1 - 0.073 12.5 0.0 0.75 9.2 0.0 2.1 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 OAF99986.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 OAF99986.1 - 0.12 11.3 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2752 PF10825.8 OAF99986.1 - 0.17 12.0 0.6 0.34 11.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) MFS_1 PF07690.16 OAF99987.1 - 2.7e-23 82.5 33.4 2.7e-23 82.5 33.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Mem_trans PF03547.18 OAF99987.1 - 0.0024 16.3 0.0 0.0024 16.3 0.0 2.1 3 0 0 3 3 3 1 Membrane transport protein Putative_PNPOx PF01243.20 OAF99988.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LapA_dom PF06305.11 OAF99988.1 - 0.041 13.7 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2198 PF09964.9 OAF99988.1 - 0.063 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) Fungal_trans PF04082.18 OAF99989.1 - 2.7e-18 66.0 0.0 4.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAF99989.1 - 0.005 16.9 6.9 0.01 15.9 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_1 PF00667.20 OAF99991.1 - 1e-58 198.5 0.0 2.4e-58 197.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAF99991.1 - 3.3e-10 40.6 0.0 1.7e-09 38.3 0.0 2.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 OAF99991.1 - 9.9e-06 25.7 0.0 3.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 OAF99991.1 - 7.9e-05 22.9 0.1 0.0002 21.6 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 OAF99991.1 - 0.013 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain Glyoxalase PF00903.25 OAF99993.1 - 6.4e-42 142.8 0.2 4.6e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAF99993.1 - 1.6e-17 63.7 0.1 6e-07 29.7 0.0 3.9 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAF99993.1 - 6.7e-10 39.7 0.0 0.00016 22.4 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAF99993.1 - 1.3e-07 31.9 0.0 0.0085 16.2 0.0 3.2 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OAF99993.1 - 6.1e-06 26.2 0.6 0.44 10.5 0.0 4.1 3 1 0 4 4 4 3 Glyoxalase-like domain DUF1338 PF07063.13 OAF99993.1 - 0.0045 16.2 0.0 6.4 5.9 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1338) NIL PF09383.10 OAF99993.1 - 0.089 12.6 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 NIL domain MoaF PF10703.9 OAF99993.1 - 0.11 12.4 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain 2-Hacid_dh_C PF02826.19 OAF99994.1 - 1.6e-57 193.7 0.1 2.8e-57 193.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAF99994.1 - 1e-37 128.8 0.5 1.7e-37 128.1 0.5 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 OAF99994.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain HIM1 PF08732.10 OAF99995.1 - 7.4e-06 25.6 0.0 9.8e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 OAF99995.1 - 1e-05 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAF99995.1 - 0.00041 19.9 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAF99995.1 - 0.00077 19.9 0.0 0.0015 19.0 0.0 1.6 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 OAF99995.1 - 0.0017 17.9 0.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 OAF99995.1 - 0.0024 17.1 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein MOSC PF03473.17 OAF99997.1 - 1.2e-20 73.9 0.0 2.9e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 OAF99997.1 - 5.7e-13 48.6 2.4 1.1e-12 47.7 2.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 OAF99997.1 - 1.1e-07 31.6 0.1 2.8e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 OAF99997.1 - 0.13 12.9 0.1 3.2 8.4 0.1 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Cation_efflux PF01545.21 OAF99999.1 - 0.0056 16.4 0.6 0.0087 15.8 0.6 1.2 1 0 0 1 1 1 1 Cation efflux family DUF3377 PF11857.8 OAF99999.1 - 0.043 13.7 0.6 3 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4330 PF14221.6 OAF99999.1 - 0.068 13.4 1.6 0.15 12.2 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4330) Glycophorin_A PF01102.18 OAF99999.1 - 0.17 12.1 1.9 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A DUF2897 PF11446.8 OAF99999.1 - 0.18 11.7 0.2 0.18 11.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Chordopox_A33R PF05966.12 OAF99999.1 - 0.26 10.5 0.1 0.46 9.7 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein MHYT PF03707.16 OAF99999.1 - 6.3 7.0 8.2 15 5.8 1.3 3.0 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat CAP PF00188.26 OAG00001.1 - 0.072 13.9 0.1 0.73 10.7 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich secretory protein family DUF1648 PF07853.11 OAG00002.1 - 0.37 10.5 3.5 2 8.1 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1648) ArabFuran-catal PF09206.11 OAG00004.1 - 9.4e-151 501.5 11.7 1.4e-150 500.9 11.7 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 OAG00004.1 - 4.2e-54 182.3 3.6 6.6e-54 181.7 3.6 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain p450 PF00067.22 OAG00005.1 - 1.3e-34 119.7 0.0 4e-34 118.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Bac_rhamnosid_C PF17390.2 OAG00007.1 - 7.4e-11 41.7 0.1 1.7e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 OAG00007.1 - 2.4e-07 30.4 0.0 9.2e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 OAG00007.1 - 0.065 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF608 PF04685.13 OAG00007.1 - 0.078 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region 3Beta_HSD PF01073.19 OAG00009.1 - 6.1e-05 22.2 0.0 0.0008 18.5 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG00009.1 - 0.00018 20.8 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAG00009.1 - 0.00079 19.0 0.0 0.0097 15.4 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_8 PF02954.19 OAG00009.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Thioredoxin PF00085.20 OAG00010.1 - 3.4e-28 97.6 0.0 4.9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAG00010.1 - 4.2e-08 33.4 0.0 5.1e-06 26.7 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAG00010.1 - 9.6e-08 32.5 0.1 3.5e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAG00010.1 - 2.6e-05 24.1 0.1 0.001 19.0 0.1 2.1 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 OAG00010.1 - 6.6e-05 22.7 0.0 8.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG00010.1 - 0.00027 20.4 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 OAG00010.1 - 0.0099 15.6 0.3 1.6 8.4 0.2 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.6 OAG00010.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 OAG00010.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 OAG00010.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin domain Ank_2 PF12796.7 OAG00011.1 - 9.9e-11 42.1 0.0 2.4e-07 31.2 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG00011.1 - 3.8e-09 36.9 0.2 0.0061 17.1 0.1 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG00011.1 - 8.8e-07 28.8 2.2 0.9 10.3 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 OAG00011.1 - 0.00011 22.4 0.3 3.6 8.0 0.0 4.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG00011.1 - 0.0085 16.5 2.4 4.3 8.0 0.1 4.6 4 1 1 5 5 5 1 Ankyrin repeat UreE_N PF02814.15 OAG00011.1 - 0.087 12.4 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Reductase_C PF14759.6 OAG00011.1 - 0.15 12.6 0.0 0.62 10.6 0.0 2.1 2 0 0 2 2 2 0 Reductase C-terminal Zn_clus PF00172.18 OAG00012.1 - 1.9e-09 37.5 9.0 3.2e-09 36.8 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG00012.1 - 4.9e-09 35.6 0.1 8.2e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phage_Arf PF17585.2 OAG00012.1 - 0.19 11.7 0.1 0.43 10.6 0.1 1.6 1 0 0 1 1 1 0 Accessory recombination function protein DUF4419 PF14388.6 OAG00014.1 - 2e-93 313.2 0.1 4.5e-93 312.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Proteasome PF00227.26 OAG00017.1 - 5.6e-60 202.1 0.0 6.7e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG00017.1 - 4.6e-13 48.6 0.1 8.8e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 OAG00017.1 - 0.027 14.0 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5624 PF18538.1 OAG00017.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) FF PF01846.19 OAG00018.1 - 4.9e-17 61.8 6.2 1e-12 48.0 0.1 3.6 3 0 0 3 3 3 3 FF domain WW PF00397.26 OAG00018.1 - 2.4e-11 43.5 4.5 9.2e-10 38.4 1.6 2.6 2 0 0 2 2 2 2 WW domain SKG6 PF08693.10 OAG00019.1 - 1.7e-05 24.2 0.0 2.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 OAG00019.1 - 0.00035 19.5 0.0 0.00045 19.2 0.0 1.2 1 0 0 1 1 1 1 Amnionless DUF4381 PF14316.6 OAG00019.1 - 0.0043 17.3 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF347 PF03988.12 OAG00019.1 - 0.0088 16.2 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) MFS_2 PF13347.6 OAG00019.1 - 0.01 14.4 0.2 0.014 14.0 0.2 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein TMEM154 PF15102.6 OAG00019.1 - 0.037 13.9 0.2 0.065 13.1 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 OAG00019.1 - 0.045 13.3 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF1180 PF06679.12 OAG00019.1 - 0.052 14.0 0.6 0.079 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) YajC PF02699.15 OAG00019.1 - 0.054 13.4 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sulf_transp PF04143.14 OAG00019.1 - 0.074 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Sulphur transport MHYT PF03707.16 OAG00019.1 - 0.089 13.0 0.2 0.18 12.0 0.2 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat EphA2_TM PF14575.6 OAG00019.1 - 0.14 13.1 0.0 0.39 11.6 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 OAG00019.1 - 0.25 11.2 1.6 0.54 10.1 1.1 1.8 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor DUF3687 PF12459.8 OAG00020.1 - 0.0094 15.4 1.4 4.9 6.7 0.8 3.5 3 0 0 3 3 3 2 D-Ala-teichoic acid biosynthesis protein SGL PF08450.12 OAG00023.1 - 1.3e-05 24.9 0.0 0.0036 16.9 0.0 2.5 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SelK_SelG PF10961.8 OAG00024.1 - 0.85 10.3 4.1 0.51 11.0 0.7 2.2 1 1 2 3 3 3 0 Selenoprotein SelK_SelG Glyco_hydro_16 PF00722.21 OAG00025.1 - 7.4e-11 41.8 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ntox17 PF15524.6 OAG00027.1 - 0.023 15.0 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Novel toxin 17 Abhydrolase_6 PF12697.7 OAG00028.1 - 0.00031 21.4 1.5 0.00054 20.6 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG00028.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAG00028.1 - 0.0028 16.6 0.3 0.02 13.8 0.3 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 OAG00028.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S9 PF00326.21 OAG00029.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 OAG00029.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase RTA1 PF04479.13 OAG00031.1 - 2.3e-71 239.7 6.9 3.9e-71 238.9 6.9 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2062 PF09835.9 OAG00031.1 - 0.2 11.5 5.8 0.82 9.5 5.8 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Cu-oxidase_2 PF07731.14 OAG00033.1 - 1.3e-37 128.6 2.9 3.2e-36 124.1 0.2 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG00033.1 - 2e-23 83.3 0.1 7.6e-23 81.4 0.0 2.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG00033.1 - 7.3e-23 80.8 6.3 2e-21 76.2 1.6 3.1 2 1 0 2 2 2 2 Multicopper oxidase SET PF00856.28 OAG00034.1 - 9.9e-12 45.6 0.1 6.9e-11 42.8 0.1 2.1 1 1 0 1 1 1 1 SET domain FAD_binding_4 PF01565.23 OAG00035.1 - 9.3e-24 83.7 1.6 9.1e-23 80.5 1.6 2.2 1 1 0 1 1 1 1 FAD binding domain DnaJ PF00226.31 OAG00036.1 - 9e-14 51.3 1.1 1.2e-13 51.0 1.1 1.1 1 0 0 1 1 1 1 DnaJ domain Med12-LCEWAV PF12145.8 OAG00036.1 - 0.0067 15.3 0.0 0.0073 15.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Trigger_C PF05698.14 OAG00036.1 - 0.093 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus ESP PF16590.5 OAG00036.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Glyoxalase_4 PF13669.6 OAG00037.1 - 1.2e-05 25.5 0.4 0.001 19.3 0.0 2.9 2 1 1 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAG00037.1 - 2.6e-05 24.4 0.1 5.7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain Ysc84 PF04366.12 OAG00038.1 - 1.2e-40 138.2 0.1 2e-40 137.5 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 OAG00038.1 - 4.3e-13 48.7 0.4 1e-12 47.4 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OAG00038.1 - 2.1e-11 43.3 0.0 4.9e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAG00038.1 - 7.7e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain F-actin_cap_A PF01267.17 OAG00039.1 - 4.2e-93 311.6 0.0 4.7e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CdiI_2 PF18593.1 OAG00039.1 - 0.11 13.1 0.0 0.53 11.0 0.0 2.0 2 0 0 2 2 2 0 CdiI immunity protein VHS PF00790.19 OAG00042.1 - 9.9e-20 70.8 0.0 2.6e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 OAG00042.1 - 5.3e-05 23.5 1.8 0.00019 21.7 1.5 2.1 1 1 1 2 2 2 1 GAT domain Macoilin PF09726.9 OAG00042.1 - 0.11 11.1 2.2 0.14 10.7 2.2 1.1 1 0 0 1 1 1 0 Macoilin family FMO-like PF00743.19 OAG00043.1 - 9.3e-57 192.6 0.0 1.1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG00043.1 - 1.7e-22 80.1 0.0 5.6e-19 68.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG00043.1 - 5.6e-16 58.6 0.0 1.5e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG00043.1 - 1.8e-08 34.5 0.0 4.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG00043.1 - 1.6e-07 31.4 0.0 0.0025 17.8 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG00043.1 - 4.2e-06 27.2 0.1 0.0066 17.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG00043.1 - 0.00014 21.6 0.1 0.058 13.0 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG00043.1 - 0.00016 20.9 0.1 0.00091 18.5 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OAG00043.1 - 0.00051 20.1 0.0 0.073 13.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG00043.1 - 0.00057 19.2 0.0 0.00094 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG00043.1 - 0.00058 18.7 0.0 0.002 16.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OAG00043.1 - 0.00098 18.4 0.2 0.0037 16.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 OAG00043.1 - 0.0015 17.9 0.5 0.0028 17.0 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 OAG00043.1 - 0.0025 18.2 0.0 0.64 10.5 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OAG00043.1 - 0.0026 16.9 0.0 0.01 15.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 OAG00043.1 - 0.016 14.5 0.1 0.33 10.2 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 OAG00043.1 - 0.061 12.7 0.1 9.2 5.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAG00043.1 - 0.065 12.8 0.1 0.83 9.2 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OAG00043.1 - 0.092 13.0 0.1 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain XdhC_C PF13478.6 OAG00043.1 - 0.19 12.2 0.0 0.67 10.5 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Insulin_TMD PF17870.1 OAG00044.1 - 0.063 13.4 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RTA1 PF04479.13 OAG00048.1 - 1.6e-13 50.7 10.4 1.6e-13 50.7 10.4 1.7 2 1 0 2 2 2 1 RTA1 like protein DUF3328 PF11807.8 OAG00049.1 - 2.4e-30 106.0 0.2 3.1e-30 105.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_11 PF08241.12 OAG00049.1 - 0.014 16.0 0.0 0.073 13.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_2 PF02230.16 OAG00050.1 - 4.3e-06 26.7 13.3 1.1 9.0 0.0 6.9 1 1 6 7 7 7 4 Phospholipase/Carboxylesterase DUF3621 PF12285.8 OAG00050.1 - 0.00014 22.2 14.9 4.1 7.9 0.1 7.0 2 2 5 7 7 7 3 Protein of unknown function (DUF3621) DUF1326 PF07040.11 OAG00050.1 - 0.0084 16.2 6.9 88 3.1 0.0 5.9 1 1 7 8 8 8 0 Protein of unknown function (DUF1326) UDPG_MGDP_dh_C PF03720.15 OAG00050.1 - 0.77 10.2 12.5 23 5.5 0.8 3.6 1 1 2 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PVL_ORF50 PF07768.11 OAG00050.1 - 3.5 8.0 38.9 37 4.7 0.5 7.0 1 1 2 3 3 3 0 PVL ORF-50-like family NDUF_B4 PF07225.12 OAG00050.1 - 6.1 6.8 18.5 23 4.9 0.6 5.0 1 1 3 6 6 6 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF3328 PF11807.8 OAG00051.1 - 1.6e-51 175.2 0.0 1.8e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_12 PF01670.16 OAG00052.1 - 1.1e-53 182.4 9.3 1.4e-53 182.1 9.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 zf-RING_2 PF13639.6 OAG00055.1 - 6.3e-12 45.6 7.2 8.7e-12 45.2 7.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG00055.1 - 2.5e-07 30.3 5.8 4.4e-07 29.5 5.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OAG00055.1 - 2.2e-06 27.9 4.2 4.1e-06 27.0 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG00055.1 - 3.6e-06 26.7 5.4 5.5e-06 26.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG00055.1 - 5.8e-06 26.1 4.2 7.8e-06 25.7 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG00055.1 - 1.8e-05 24.5 4.0 2.8e-05 23.9 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG00055.1 - 7.1e-05 22.6 5.0 0.00011 21.9 5.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG00055.1 - 0.00017 21.5 4.9 0.00024 21.0 4.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG00055.1 - 0.00041 20.3 2.4 0.0019 18.2 2.9 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAG00055.1 - 0.011 15.8 4.9 0.023 14.8 4.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 OAG00055.1 - 0.026 14.4 4.4 0.026 14.4 4.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 OAG00055.1 - 0.093 12.4 5.4 0.19 11.3 5.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rax2 PF12768.7 OAG00055.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Carn_acyltransf PF00755.20 OAG00055.1 - 0.16 10.6 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 OAG00056.1 - 5.7e-23 81.4 25.2 5.7e-23 81.4 25.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MF_alpha_N PF05436.11 OAG00058.1 - 0.031 14.2 0.1 0.034 14.0 0.1 1.1 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Aminotran_4 PF01063.19 OAG00059.1 - 3.6e-17 63.0 0.2 3.5e-11 43.4 0.0 3.0 2 1 0 3 3 3 2 Amino-transferase class IV TPR_2 PF07719.17 OAG00060.1 - 1.1e-33 112.6 26.2 0.00021 21.2 0.1 11.5 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 OAG00060.1 - 1.3e-31 107.1 28.5 0.00046 19.9 0.2 11.5 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 OAG00060.1 - 7.3e-21 74.5 14.0 4.1e-06 27.3 2.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG00060.1 - 1.3e-17 62.4 21.5 0.011 15.9 0.1 10.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG00060.1 - 8.5e-17 60.6 25.5 0.00068 19.3 0.0 8.3 7 1 1 8 8 8 5 TPR repeat TPR_17 PF13431.6 OAG00060.1 - 9.1e-16 57.0 13.4 8.1e-05 22.7 0.0 8.3 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAG00060.1 - 4.8e-13 49.4 16.5 4e-05 24.0 0.5 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG00060.1 - 4.9e-13 49.2 29.0 0.0019 18.5 0.3 8.2 3 1 6 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAG00060.1 - 9.4e-10 38.5 18.8 0.0024 18.6 1.5 7.7 5 2 4 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG00060.1 - 3e-08 33.7 15.4 0.00028 21.0 1.6 5.7 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG00060.1 - 6.4e-08 32.1 21.9 0.05 13.6 0.1 9.1 9 1 1 10 10 9 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 OAG00060.1 - 2.8e-06 26.7 12.1 0.46 10.0 0.2 5.8 5 0 0 5 5 5 3 SHNi-TPR ANAPC3 PF12895.7 OAG00060.1 - 5.1e-06 26.6 13.1 0.18 12.1 0.2 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 OAG00060.1 - 7.6e-06 25.5 1.5 7.6e-06 25.5 1.5 2.3 1 1 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 OAG00060.1 - 8.2e-06 25.5 27.4 0.029 14.2 0.2 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAG00060.1 - 0.00093 19.3 5.0 5 7.2 0.0 5.5 4 1 0 5 5 5 1 Domain of Unknown Function (DUF3856) HrpB1_HrpK PF09613.10 OAG00060.1 - 0.032 13.9 0.2 0.46 10.1 0.3 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) MAS20 PF02064.15 OAG00060.1 - 0.034 14.2 13.9 0.7 10.0 0.9 4.8 4 2 1 5 5 5 0 MAS20 protein import receptor RNA_pol_Rpc4 PF05132.14 OAG00060.1 - 0.04 14.3 0.7 0.094 13.1 0.7 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 TAF1_subA PF14929.6 OAG00060.1 - 0.045 13.2 1.9 0.2 11.0 0.4 2.5 2 1 0 2 2 2 0 TAF RNA Polymerase I subunit A Sel1 PF08238.12 OAG00060.1 - 0.65 10.8 5.8 1.6 9.5 0.0 4.1 4 0 0 4 4 3 0 Sel1 repeat TPR_6 PF13174.6 OAG00060.1 - 0.92 10.3 21.1 2.2 9.1 0.0 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAG00060.1 - 1.7 8.7 12.9 14 5.8 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 OAG00060.1 - 3.4 7.8 19.6 8.1 6.6 0.1 5.9 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 OAG00060.1 - 3.7 7.9 11.4 1.8 9.0 0.6 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat PRELI PF04707.14 OAG00061.1 - 1.3e-22 80.3 0.0 5.4e-20 71.8 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.25 OAG00062.1 - 2.2e-19 69.9 0.6 5e-19 68.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Chitin_synth_1 PF01644.17 OAG00063.1 - 1e-75 253.2 0.4 1.7e-75 252.5 0.4 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAG00063.1 - 1.1e-29 102.2 0.0 2e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG00063.1 - 1.3e-20 73.5 9.0 1.1e-16 60.6 0.1 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG00063.1 - 3.1e-05 24.0 12.0 3.1e-05 24.0 12.0 3.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 zf-CCHC PF00098.23 OAG00065.1 - 1.7e-26 91.0 47.6 6.2e-06 26.0 1.2 6.5 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 OAG00065.1 - 6.6e-07 29.0 39.0 0.0032 17.2 0.2 6.4 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 OAG00065.1 - 4e-05 23.2 29.5 0.15 11.8 0.9 6.0 5 1 1 6 6 6 5 Zinc knuckle Pkinase PF00069.25 OAG00066.1 - 1.4e-74 250.8 0.0 1.9e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00066.1 - 8.4e-39 133.4 0.0 1.2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 OAG00066.1 - 4.1e-18 65.9 0.0 5.8e-08 33.2 0.0 3.5 3 0 0 3 3 3 3 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 OAG00066.1 - 2e-16 59.8 0.0 4.1e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 OAG00066.1 - 4.6e-06 26.2 0.0 2.3e-05 23.9 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG00066.1 - 0.0015 17.6 0.1 0.0029 16.6 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OAG00066.1 - 0.0066 16.1 0.5 0.039 13.6 0.1 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 OAG00066.1 - 0.033 13.5 0.0 0.085 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 OAG00066.1 - 0.1 11.4 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 OAG00066.1 - 0.11 12.4 0.2 0.45 10.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3455 PF11937.8 OAG00068.1 - 2.7e-35 122.1 0.7 3.5e-35 121.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) p450 PF00067.22 OAG00069.1 - 9.3e-36 123.6 0.0 1.3e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG00070.1 - 2.3e-64 217.9 0.0 3e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_4 PF13669.6 OAG00070.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LMWPc PF01451.21 OAG00073.1 - 2.9e-31 108.8 0.0 4.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Transthyretin PF00576.21 OAG00074.1 - 5e-37 126.9 0.0 6.1e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Big_1 PF02369.16 OAG00074.1 - 0.015 15.3 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) GCP_C_terminal PF04130.13 OAG00076.1 - 2.4e-97 326.2 0.0 3.7e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAG00076.1 - 2.6e-81 273.6 0.0 1.1e-80 271.6 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal BTB PF00651.31 OAG00077.1 - 4.8e-05 23.6 0.4 0.0014 18.8 0.0 2.6 2 1 0 2 2 2 1 BTB/POZ domain Aft1_HRA PF11786.8 OAG00078.1 - 1.3e-21 76.7 11.2 1.3e-21 76.7 11.2 3.3 2 2 1 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.8 OAG00078.1 - 8.2e-16 58.9 7.9 8.2e-16 58.9 7.9 3.5 3 0 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 OAG00078.1 - 6.3e-15 55.4 14.3 1.9e-14 53.8 10.0 3.1 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 OAG00078.1 - 9.4e-13 48.1 5.3 2e-12 47.0 5.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG00078.1 - 3.4e-05 23.8 5.7 7e-05 22.8 5.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG00078.1 - 0.004 17.6 2.2 0.004 17.6 2.2 2.6 2 1 1 3 3 3 1 bZIP Maf transcription factor DUF4711 PF15829.5 OAG00078.1 - 1.1 9.2 3.2 0.68 9.8 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4711) WAP PF00095.21 OAG00080.1 - 0.00013 22.3 26.8 0.00038 20.8 10.6 3.3 1 1 2 3 3 3 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' EB PF01683.18 OAG00080.1 - 0.05 13.9 6.5 0.05 13.9 6.5 3.2 2 1 0 3 3 3 0 EB module Nodulin_late PF07127.11 OAG00080.1 - 0.17 12.2 0.6 0.17 12.2 0.6 3.1 2 1 1 3 3 3 0 Late nodulin protein Conotoxin_I2 PF17557.2 OAG00080.1 - 0.7 10.1 38.7 0.29 11.3 9.7 3.6 1 1 3 4 4 4 0 I2-superfamily conotoxins Glyco_hydro_72 PF03198.14 OAG00081.1 - 2.7e-98 329.1 0.5 3.6e-98 328.7 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase F-box-like PF12937.7 OAG00083.1 - 0.0002 21.2 1.2 0.0005 19.9 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG00083.1 - 0.047 13.6 0.6 0.12 12.3 0.6 1.7 1 0 0 1 1 1 0 F-box domain GST_N PF02798.20 OAG00084.1 - 7.4e-14 51.9 0.0 3.8e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG00084.1 - 1.6e-10 41.0 0.0 4.5e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG00084.1 - 1e-07 32.2 0.0 2.4e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG00084.1 - 7.6e-07 29.5 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG00084.1 - 6.2e-06 26.1 0.0 1.8e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG00084.1 - 1.8e-05 24.9 0.0 6.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MAJIN PF15077.6 OAG00089.1 - 9.4 5.9 11.8 18 5.0 11.8 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein zf-piccolo PF05715.13 OAG00090.1 - 0.35 11.0 10.2 0.25 11.5 3.0 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger DUF2231 PF09990.9 OAG00092.1 - 3.4 8.1 11.8 0.38 11.2 0.5 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF846 PF05832.12 OAG00092.1 - 8.5 6.4 13.8 0.12 12.4 5.4 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) DUF3328 PF11807.8 OAG00093.1 - 4.3e-37 128.0 1.9 5.9e-37 127.6 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HypF_C PF17788.1 OAG00093.1 - 0.07 13.8 0.2 0.12 13.1 0.2 1.3 1 0 0 1 1 1 0 HypF Kae1-like domain DMRT-like PF15791.5 OAG00094.1 - 0.057 13.8 0.0 12 6.4 0.0 2.4 1 1 1 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 PepSY_TM_like_2 PF16357.5 OAG00095.1 - 0.046 13.7 0.4 0.067 13.2 0.4 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like Glyco_hydro_43 PF04616.14 OAG00096.1 - 4.5e-33 114.8 8.3 6.7e-33 114.2 8.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG00096.1 - 6.6e-24 84.8 1.7 6.6e-24 84.8 1.7 1.7 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain EPSP_synthase PF00275.20 OAG00097.1 - 4.1e-126 421.1 0.0 6.2e-126 420.5 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 OAG00097.1 - 1.3e-102 342.5 0.1 2.9e-102 341.3 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 OAG00097.1 - 1.9e-57 195.2 0.0 5.7e-57 193.6 0.0 1.9 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 OAG00097.1 - 1e-37 129.7 0.0 1.2e-36 126.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 OAG00097.1 - 1.3e-20 73.5 0.0 3e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 OAG00097.1 - 3.3e-08 33.1 0.0 8.6e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 OAG00097.1 - 3.4e-07 30.2 0.0 1.9e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 OAG00097.1 - 0.015 15.3 0.0 0.06 13.4 0.0 2.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_S8 PF00082.22 OAG00098.1 - 7.9e-33 114.0 9.3 1.2e-32 113.4 9.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG00098.1 - 2.9e-09 37.5 0.0 5.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 ECR1_N PF14382.6 OAG00098.1 - 1.2 9.0 6.1 15 5.4 0.2 3.7 4 0 0 4 4 4 0 Exosome complex exonuclease RRP4 N-terminal region Syndecan PF01034.20 OAG00099.1 - 0.083 12.8 1.1 0.14 12.1 1.1 1.2 1 0 0 1 1 1 0 Syndecan domain MadM PF03818.13 OAG00099.1 - 0.13 12.1 1.3 0.23 11.4 1.3 1.4 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit Amnionless PF14828.6 OAG00099.1 - 0.17 10.7 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless Oxidored_molyb PF00174.19 OAG00100.1 - 6.3e-48 162.6 0.0 1.1e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG00100.1 - 2.1e-12 47.2 0.3 5e-12 46.0 0.3 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain p450 PF00067.22 OAG00101.1 - 2.1e-31 109.2 0.0 1.1e-27 97.0 0.0 2.1 1 1 0 2 2 2 2 Cytochrome P450 Phage_holin_2_4 PF16082.5 OAG00101.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DAO PF01266.24 OAG00103.1 - 1.4e-36 126.8 0.3 1.6e-36 126.6 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG00103.1 - 0.0014 18.8 0.1 0.0035 17.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG00103.1 - 0.0058 16.6 0.4 0.086 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG00103.1 - 0.0098 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DUF1289 PF06945.13 OAG00104.1 - 0.14 12.0 0.1 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Sporozoite_P67 PF05642.11 OAG00105.1 - 0.0063 14.7 3.8 0.0065 14.6 3.8 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Gly-zipper_Omp PF13488.6 OAG00105.1 - 0.13 12.3 32.5 1.5 8.9 6.5 2.3 1 1 1 2 2 2 0 Glycine zipper DUF1269 PF06897.12 OAG00105.1 - 3.2 8.1 17.1 0.094 13.0 9.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) Gly-zipper_OmpA PF13436.6 OAG00105.1 - 7.5 6.4 29.3 0.35 10.7 15.5 2.7 1 1 1 2 2 2 0 Glycine-zipper domain DUF4448 PF14610.6 OAG00106.1 - 0.00037 20.3 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OAG00106.1 - 0.003 17.4 3.6 0.0059 16.5 3.6 1.5 1 1 0 1 1 1 1 TMEM154 protein family Glyco_hydro_26 PF02156.15 OAG00107.1 - 5.7e-10 39.1 0.6 8.1e-10 38.6 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Cellulase PF00150.18 OAG00107.1 - 0.041 13.3 0.5 0.36 10.2 0.2 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DUF1479 PF07350.12 OAG00107.1 - 0.048 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Carboxyl_trans PF01039.22 OAG00108.1 - 6.6e-81 272.4 0.0 8.4e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAG00109.1 - 3.5e-57 193.3 0.0 7.1e-57 192.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 OAG00109.1 - 3.6e-33 113.9 0.0 1.1e-32 112.3 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 OAG00109.1 - 4e-28 98.2 0.0 1e-27 96.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 OAG00109.1 - 1.1e-13 50.8 1.5 2.3e-13 49.7 1.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG00109.1 - 2.5e-08 33.7 0.0 4.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG00109.1 - 1.4e-06 28.0 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG00109.1 - 5e-06 26.7 0.0 9.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAG00109.1 - 9.8e-05 22.1 0.1 9.8e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like DUF2118 PF09891.9 OAG00109.1 - 0.00019 21.4 0.4 0.00049 20.1 0.3 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 OAG00109.1 - 0.016 15.2 0.2 0.034 14.1 0.2 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 OAG00109.1 - 0.023 14.0 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GTP_EFTU PF00009.27 OAG00110.1 - 1.3e-48 165.2 0.0 2e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 OAG00110.1 - 1.3e-20 73.4 2.9 2.7e-20 72.5 2.9 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 OAG00110.1 - 7.6e-08 32.6 0.0 2.2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAG00110.1 - 1.1e-07 31.9 0.0 0.0003 20.8 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase Transferrin PF00405.17 OAG00110.1 - 0.00063 19.0 0.2 0.53 9.4 0.1 2.2 2 0 0 2 2 2 2 Transferrin Ras PF00071.22 OAG00110.1 - 0.0019 17.8 0.3 0.014 15.0 0.1 2.2 2 0 0 2 2 2 1 Ras family Roc PF08477.13 OAG00110.1 - 0.002 18.3 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 OAG00110.1 - 0.031 14.7 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 2 FeoB_N PF02421.18 OAG00110.1 - 0.086 12.4 0.2 1.3 8.6 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B CysA_C_terminal PF17850.1 OAG00110.1 - 0.12 12.9 0.0 0.46 11.1 0.0 2.0 1 0 0 1 1 1 0 CysA C-terminal regulatory domain SRPRB PF09439.10 OAG00110.1 - 0.14 11.6 0.0 7.6 5.9 0.0 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_hydro_61 PF03443.14 OAG00111.1 - 1.1e-24 87.6 0.0 1.5e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PTPA PF03095.15 OAG00113.1 - 1.9e-117 392.0 0.0 2.3e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SAP PF02037.27 OAG00114.1 - 0.00085 19.0 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 SAP domain Peptidase_C2 PF00648.21 OAG00115.1 - 9.6e-66 221.8 1.1 6.6e-43 146.8 0.1 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease AvrLm4-7 PF18661.1 OAG00115.1 - 2.2 9.4 4.7 0.41 11.7 0.4 2.0 2 0 0 2 2 2 0 Avirulence Effector AvrLm4-7 Fungal_trans PF04082.18 OAG00119.1 - 2.1e-15 56.5 0.0 3.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG00119.1 - 5.1e-06 26.5 9.5 5.1e-06 26.5 9.5 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG00120.1 - 3e-35 121.8 32.6 3e-35 121.8 32.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 OAG00120.1 - 0.0016 18.2 0.3 0.0016 18.2 0.3 2.5 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) zf-CCCH_3 PF15663.5 OAG00121.1 - 0.00023 21.4 6.1 0.23 11.7 0.5 4.1 1 1 2 3 3 3 2 Zinc-finger containing family 5_nucleotid_C PF02872.18 OAG00122.1 - 6.6e-37 127.2 0.1 1.8e-36 125.8 0.1 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OAG00122.1 - 6e-10 40.0 0.6 1.3e-09 38.9 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase BUD22 PF09073.10 OAG00123.1 - 3.1e-81 273.9 26.7 4.3e-81 273.5 26.7 1.2 1 0 0 1 1 1 1 BUD22 Spot_14 PF07084.12 OAG00123.1 - 2 8.5 5.0 0.26 11.4 0.4 1.9 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 PAN_4 PF14295.6 OAG00125.1 - 0.016 15.1 1.3 0.043 13.7 1.3 1.7 1 0 0 1 1 1 0 PAN domain SIS PF01380.22 OAG00127.1 - 1.1e-12 47.9 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 OAG00127.1 - 0.00017 21.6 0.1 0.013 15.5 0.0 2.3 1 1 1 2 2 2 2 SIS domain Acetyltransf_1 PF00583.25 OAG00128.1 - 1e-09 38.6 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG00128.1 - 2.9e-05 24.4 0.0 4.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG00128.1 - 0.0002 21.3 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG00128.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein LEM PF03020.15 OAG00128.1 - 0.029 13.9 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 LEM domain MFS_1 PF07690.16 OAG00129.1 - 4.9e-21 75.0 53.8 1.6e-20 73.3 41.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily YabA PF06156.13 OAG00130.1 - 0.038 14.6 0.1 0.75 10.5 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Trimer_CC PF08954.11 OAG00130.1 - 0.2 11.3 1.2 3.5 7.2 0.4 2.4 2 0 0 2 2 2 0 Trimerisation motif Gly_transf_sug PF04488.15 OAG00131.1 - 5.4e-10 39.8 0.1 1e-09 38.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OAG00131.1 - 5.2e-08 32.6 0.4 7.7e-08 32.0 0.4 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Sugar_tr PF00083.24 OAG00132.1 - 1.3e-89 301.1 27.7 1.5e-89 300.9 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00132.1 - 1.4e-24 86.7 53.9 1.9e-19 69.8 23.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4690 PF15756.5 OAG00133.1 - 0.035 14.7 0.0 0.086 13.4 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Doppel PF11466.8 OAG00133.1 - 0.31 10.7 1.7 0.55 9.9 1.7 1.4 1 0 0 1 1 1 0 Prion-like protein Doppel Podoplanin PF05808.11 OAG00133.1 - 0.47 10.5 1.9 0.65 10.1 1.2 1.6 1 1 1 2 2 2 0 Podoplanin DUF1769 PF08588.10 OAG00134.1 - 9.1e-24 83.4 0.7 2.3e-23 82.2 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Gpi16 PF04113.14 OAG00136.1 - 1.8e-230 766.2 0.0 2.4e-230 765.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 OAG00137.1 - 5.8e-64 216.2 1.1 7.2e-64 215.8 1.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus GRP PF07172.11 OAG00137.1 - 6.5 7.5 27.3 5.2 7.8 25.1 1.9 2 0 0 2 2 2 0 Glycine rich protein family Asp PF00026.23 OAG00138.1 - 2.5e-32 112.6 0.0 2e-31 109.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG00138.1 - 7.6e-06 26.3 0.0 0.00021 21.6 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG00138.1 - 1.9e-05 25.2 0.0 0.13 12.9 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG00138.1 - 0.00024 21.6 0.0 0.12 13.0 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAG00138.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF1664 PF07889.12 OAG00139.1 - 0.00028 20.9 5.3 0.12 12.4 0.1 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) LXG PF04740.12 OAG00139.1 - 0.00037 20.3 0.6 0.0019 18.0 0.0 2.2 1 1 0 1 1 1 1 LXG domain of WXG superfamily KxDL PF10241.9 OAG00139.1 - 0.00047 20.4 1.0 0.092 13.0 0.0 3.7 1 1 3 4 4 4 1 Uncharacterized conserved protein Filament PF00038.21 OAG00139.1 - 0.0013 18.4 0.7 0.048 13.2 0.4 2.1 1 1 1 2 2 2 1 Intermediate filament protein NPV_P10 PF05531.12 OAG00139.1 - 0.0023 18.4 3.5 0.99 9.9 0.5 3.5 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 OAG00139.1 - 0.013 15.5 1.9 3 7.9 0.1 2.7 1 1 2 3 3 3 0 Laminin Domain II CALCOCO1 PF07888.11 OAG00139.1 - 0.019 13.9 1.5 0.036 12.9 1.5 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like EzrA PF06160.12 OAG00139.1 - 0.035 12.3 1.0 2.3 6.3 0.1 2.4 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 OAG00139.1 - 0.038 12.9 1.4 0.39 9.6 1.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 OAG00139.1 - 0.073 12.0 0.2 1.7 7.5 0.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Y_phosphatase3 PF13350.6 OAG00139.1 - 0.082 12.9 0.5 3.1 7.7 0.1 2.6 2 1 0 2 2 2 0 Tyrosine phosphatase family DUF16 PF01519.16 OAG00139.1 - 0.1 13.1 2.2 1.2 9.7 1.8 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 SesA PF17107.5 OAG00139.1 - 0.16 12.2 2.8 0.16 12.2 1.4 1.7 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HrpB7 PF09486.10 OAG00139.1 - 0.58 10.5 8.5 0.21 12.0 2.6 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Baculo_PEP_C PF04513.12 OAG00139.1 - 1.7 8.7 8.7 41 4.2 9.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DEAD PF00270.29 OAG00141.1 - 1.3e-40 139.0 0.0 2.3e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG00141.1 - 4.6e-25 88.1 0.0 1.2e-24 86.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG00141.1 - 1e-05 25.6 1.7 4.3e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAG00141.1 - 0.058 13.7 0.1 0.18 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain Peptidase_S30 PF01577.16 OAG00141.1 - 8 6.0 13.7 0.65 9.6 0.1 2.5 2 0 0 2 2 2 0 Potyvirus P1 protease FtsJ PF01728.19 OAG00142.1 - 4.8e-64 215.7 0.0 6.2e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase UPF0146 PF03686.13 OAG00142.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Nucleotid_trans PF03407.16 OAG00143.1 - 1.3e-06 28.6 1.1 2.1e-06 27.9 1.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 OAG00143.1 - 0.00074 19.3 4.8 0.036 13.8 3.6 2.1 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 OAG00143.1 - 0.019 14.6 2.7 0.076 12.6 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF273 PsbI PF02532.14 OAG00143.1 - 0.68 9.9 4.6 1.3 9.0 4.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF4551 PF15087.6 OAG00144.1 - 3.4 6.4 4.0 5.3 5.7 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Bac_rhamnosid6H PF17389.2 OAG00146.1 - 4e-16 59.2 3.5 1.2e-14 54.4 2.7 2.2 1 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 OAG00146.1 - 0.0028 17.4 0.1 0.0084 15.9 0.1 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 OAG00146.1 - 0.025 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Abhydrolase_1 PF00561.20 OAG00147.1 - 8.4e-17 61.7 0.0 1.3e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG00147.1 - 2.1e-10 41.6 0.0 3.6e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OAG00147.1 - 0.095 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Glyco_hydro_28 PF00295.17 OAG00148.1 - 1e-38 133.2 7.6 1.4e-38 132.7 7.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 OAG00148.1 - 4.9 7.0 28.1 7.7 6.3 25.8 2.5 1 1 1 2 2 2 0 Right handed beta helix region YrhK PF14145.6 OAG00149.1 - 0.0015 18.4 4.8 0.0015 18.4 4.8 2.4 2 1 0 2 2 2 1 YrhK-like protein F-box PF00646.33 OAG00150.1 - 3.4e-06 26.8 1.1 1.3e-05 24.9 0.2 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG00150.1 - 7.1e-05 22.6 0.5 7.1e-05 22.6 0.5 2.3 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 OAG00150.1 - 0.00071 19.4 0.1 0.0015 18.4 0.1 1.6 1 0 0 1 1 1 1 F-box Trp_DMAT PF11991.8 OAG00151.1 - 3.9e-87 293.0 0.0 5.3e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Transket_pyr PF02779.24 OAG00152.1 - 2.8e-47 160.7 0.1 4e-47 160.2 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG00152.1 - 4e-35 120.4 0.1 3.1e-33 114.3 0.1 2.2 2 0 0 2 2 2 2 Transketolase, C-terminal domain PFOR_II PF17147.4 OAG00152.1 - 0.0024 18.1 0.0 0.0095 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF21 PF01595.20 OAG00153.1 - 6.7e-34 117.1 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAG00153.1 - 1.1e-05 25.8 0.3 0.0084 16.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain UPF0239 PF06783.11 OAG00153.1 - 9.6 6.5 7.9 46 4.3 4.6 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) Acetyltransf_10 PF13673.7 OAG00154.1 - 3e-08 33.6 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG00154.1 - 4.6e-08 33.4 0.1 2.2e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG00154.1 - 0.00023 21.4 0.0 0.0004 20.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG00154.1 - 0.0079 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAG00154.1 - 0.022 14.8 0.2 0.039 14.0 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 OAG00155.1 - 2e-73 247.8 19.9 2.3e-73 247.6 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00155.1 - 7.4e-26 90.9 25.9 7.2e-24 84.4 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG00155.1 - 0.37 9.0 7.8 1.3 7.2 0.8 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ATP_synt_H PF05493.13 OAG00155.1 - 9.4 6.8 10.9 3.4 8.2 2.2 3.0 2 0 0 2 2 2 0 ATP synthase subunit H MFS_1 PF07690.16 OAG00156.1 - 1.7e-14 53.6 17.2 2.4e-14 53.1 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1127 PF06568.11 OAG00156.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) Mannosidase_ig PF17786.1 OAG00157.1 - 3.2e-15 56.5 0.1 2e-14 54.0 0.1 2.4 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAG00157.1 - 4.2e-07 30.6 0.2 1.8e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 OAG00157.1 - 0.00013 21.6 0.0 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 OAG00157.1 - 0.0005 19.3 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OAG00157.1 - 0.0086 16.0 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.24 OAG00158.1 - 1.8e-88 297.4 23.8 2.2e-88 297.1 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00158.1 - 5.2e-28 98.0 22.1 5.2e-28 98.0 22.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily YARHG PF13308.6 OAG00158.1 - 0.034 14.0 0.0 0.096 12.6 0.0 1.7 2 0 0 2 2 2 0 YARHG domain Coat_X PF07552.11 OAG00158.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Spore Coat Protein X and V domain adh_short PF00106.25 OAG00159.1 - 7.9e-25 87.4 0.0 2e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00159.1 - 2.2e-16 60.2 0.0 2.3e-14 53.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00159.1 - 1.6e-06 28.1 0.1 2.4e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG00159.1 - 0.03 13.7 0.0 0.058 12.8 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Chromo PF00385.24 OAG00160.1 - 2.7e-13 49.6 2.1 4.5e-13 48.9 0.1 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OAG00160.1 - 2.8e-11 43.3 3.7 3.5e-10 39.8 0.1 2.8 3 1 0 3 3 3 2 Chromo shadow domain Cpn60_TCP1 PF00118.24 OAG00161.1 - 3.4e-159 530.6 6.7 3.9e-159 530.4 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 OAG00161.1 - 0.35 11.1 2.8 7.5 6.7 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain DUF3295 PF11702.8 OAG00163.1 - 3.1e-142 475.4 47.9 5.8e-142 474.5 47.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 OAG00163.1 - 1.5e-07 31.1 0.4 3.4e-07 30.0 0.4 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CENP-B_dimeris PF09026.10 OAG00163.1 - 0.21 12.0 8.4 0.41 11.1 8.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 OAG00163.1 - 0.27 11.3 4.3 0.58 10.2 4.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal YL1 PF05764.13 OAG00163.1 - 3.4 7.7 15.2 6 6.9 12.0 2.4 2 0 0 2 2 2 0 YL1 nuclear protein NB-ARC PF00931.22 OAG00166.1 - 5.7e-15 55.2 0.1 8.6e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 OAG00166.1 - 3.5e-08 33.8 0.1 1.4e-07 31.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG00166.1 - 5.9e-08 33.3 1.3 1.3e-07 32.2 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain HET PF06985.11 OAG00166.1 - 2.3e-06 28.0 2.8 1.4e-05 25.5 2.8 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATPase_2 PF01637.18 OAG00166.1 - 1.2e-05 25.4 0.0 3.6e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 OAG00166.1 - 9.8e-05 22.8 0.0 0.00089 19.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OAG00166.1 - 0.00033 20.1 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 OAG00166.1 - 0.0011 18.9 0.1 0.0034 17.3 0.1 1.9 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 OAG00166.1 - 0.0023 17.7 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 OAG00166.1 - 0.009 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase AAA_5 PF07728.14 OAG00166.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AnkUBD PF18418.1 OAG00166.1 - 0.041 14.0 0.1 0.093 12.9 0.1 1.6 1 0 0 1 1 1 0 Ankyrin ubiquitin-binding domain AAA_25 PF13481.6 OAG00166.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DoxD PF04173.13 OAG00166.1 - 0.17 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 TQO small subunit DoxD Rrn6 PF10214.9 OAG00170.1 - 0.027 13.0 15.4 0.046 12.2 15.4 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AAA_11 PF13086.6 OAG00170.1 - 0.63 9.8 7.6 1 9.1 7.6 1.3 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 OAG00170.1 - 1 7.6 7.4 1.3 7.2 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5401 PF17380.2 OAG00170.1 - 1.8 6.5 23.8 2.8 5.9 23.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Flot PF15975.5 OAG00170.1 - 2.5 8.3 5.0 4.7 7.4 5.0 1.4 1 0 0 1 1 1 0 Flotillin Nucleo_P87 PF07267.11 OAG00170.1 - 3.5 6.4 24.0 1.2 7.9 17.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Asp-B-Hydro_N PF05279.11 OAG00170.1 - 4.5 7.3 10.7 7.1 6.6 10.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1676 PF07898.13 OAG00170.1 - 7 6.7 7.1 5 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Peptidase_M14 PF00246.24 OAG00172.1 - 2.3e-42 145.8 0.6 3e-42 145.4 0.6 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 OAG00172.1 - 0.17 10.9 0.2 0.6 9.1 0.2 2.1 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family RAP80_UIM PF18282.1 OAG00172.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif DUF4491 PF14898.6 OAG00173.1 - 0.13 12.8 0.9 0.23 11.9 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) PT-VENN PF04829.13 OAG00173.1 - 0.56 10.3 7.6 0.38 10.9 5.4 1.8 1 1 1 2 2 2 0 Pre-toxin domain with VENN motif p450 PF00067.22 OAG00176.1 - 2.9e-77 260.4 0.0 3.3e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CN_hydrolase PF00795.22 OAG00178.1 - 1.8e-45 155.3 0.0 2.3e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-MYND PF01753.18 OAG00179.1 - 2.5e-09 37.0 9.0 5.2e-09 36.1 9.0 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OAG00179.1 - 2.2 8.7 9.6 5 7.5 9.6 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Myb_DNA-bind_2 PF08914.11 OAG00180.1 - 3.4e-22 78.4 0.4 7.5e-22 77.3 0.4 1.6 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 OAG00180.1 - 3e-18 65.7 0.2 4.4e-16 58.7 0.0 2.7 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 OAG00180.1 - 1.9e-11 44.2 0.0 8e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain HMG_box PF00505.19 OAG00180.1 - 3.4e-08 33.8 0.6 1.2e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box Rap1-DNA-bind PF09197.10 OAG00180.1 - 3.2e-05 24.5 0.0 3.2e-05 24.5 0.0 2.5 2 1 1 3 3 3 1 Rap1, DNA-binding HMG_box_2 PF09011.10 OAG00180.1 - 0.00047 20.7 0.1 0.0012 19.4 0.1 1.7 1 0 0 1 1 1 1 HMG-box domain DHHC PF01529.20 OAG00181.1 - 3e-34 118.0 0.9 3e-34 118.0 0.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Chisel PF15355.6 OAG00182.1 - 0.095 12.9 0.2 0.32 11.3 0.1 1.9 1 1 1 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel Med13_C PF06333.12 OAG00183.1 - 1.7e-68 231.4 1.2 1.7e-68 231.4 1.2 2.4 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 OAG00183.1 - 7.1e-48 163.6 0.5 1.3e-47 162.7 0.5 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 OAG00183.1 - 4e-30 105.4 0.6 4.1e-28 98.8 0.6 3.0 1 1 0 1 1 1 1 MID domain of medPIWI Cytomega_UL20A PF05984.12 OAG00183.1 - 0.078 13.3 1.0 0.28 11.5 1.0 1.9 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein NUC153 PF08159.12 OAG00184.1 - 1.7e-09 37.3 2.8 3.7e-09 36.2 2.8 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 OAG00184.1 - 0.001 19.8 0.1 41 5.3 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG00184.1 - 0.06 13.6 0.0 2.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cyt-b5 PF00173.28 OAG00185.1 - 1.3e-21 76.5 0.2 1.8e-21 76.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VHS PF00790.19 OAG00186.1 - 4.1e-35 120.7 1.3 5.3e-35 120.3 0.3 1.7 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 OAG00186.1 - 3.4e-17 61.8 0.0 7.1e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG00186.1 - 3e-15 55.8 0.1 5.7e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG00186.1 - 5.4e-13 48.4 0.0 1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 OAG00186.1 - 3.3e-11 43.3 1.4 4.8e-11 42.8 0.6 1.7 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 OAG00186.1 - 0.022 14.6 4.3 0.056 13.4 4.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Pox_P4A PF03395.14 OAG00186.1 - 0.26 8.8 0.1 0.41 8.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus P4A protein Hrs_helical PF12210.8 OAG00186.1 - 0.39 11.3 2.3 0.28 11.8 0.2 1.8 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pkinase PF00069.25 OAG00188.1 - 7.3e-72 241.9 0.0 1e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00188.1 - 2.3e-44 151.6 0.0 3.9e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OAG00188.1 - 5.2e-23 81.2 0.3 1.1e-22 80.1 0.3 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 OAG00188.1 - 2.5e-07 30.3 0.0 4.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG00188.1 - 9.7e-07 27.9 0.0 2.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAG00188.1 - 0.0071 15.7 0.4 0.077 12.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 OAG00188.1 - 0.028 14.1 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Haspin_kinase PF12330.8 OAG00188.1 - 0.044 12.7 0.7 0.14 11.1 0.7 1.7 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 OAG00188.1 - 0.17 11.5 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAG00188.1 - 0.29 11.0 2.8 0.47 10.3 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cation_ATPase_C PF00689.21 OAG00191.1 - 3.9e-11 43.0 1.6 7e-11 42.2 1.6 1.5 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus Transketolase_N PF00456.21 OAG00192.1 - 8.9e-120 399.6 0.0 1.5e-119 398.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG00192.1 - 3.6e-39 134.3 0.0 6.4e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG00192.1 - 1.2e-06 28.4 0.0 8.6e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG00192.1 - 1.2e-05 24.7 0.0 5.4e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase COX15-CtaA PF02628.15 OAG00194.1 - 3e-110 368.3 7.0 3.7e-110 368.0 7.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumarate_red_C PF02300.17 OAG00194.1 - 0.02 15.0 5.6 2.3 8.3 0.1 3.6 3 1 1 4 4 4 0 Fumarate reductase subunit C PQ-loop PF04193.14 OAG00194.1 - 0.2 11.4 3.7 9 6.2 0.2 2.7 2 0 0 2 2 2 0 PQ loop repeat adh_short PF00106.25 OAG00195.1 - 1e-41 142.5 0.1 1.3e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00195.1 - 5.2e-37 127.6 0.2 6.6e-37 127.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00195.1 - 1.3e-15 57.8 0.2 1.9e-15 57.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG00195.1 - 0.00057 19.1 0.0 0.00079 18.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 OAG00195.1 - 0.0051 16.5 0.1 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF484 PF04340.12 OAG00195.1 - 0.069 12.8 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 DUF2937 PF11157.8 OAG00195.1 - 0.14 11.9 0.4 0.25 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Sugar_tr PF00083.24 OAG00197.1 - 4.3e-97 325.8 18.5 5.1e-97 325.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00197.1 - 1.3e-24 86.8 16.6 1.3e-24 86.8 16.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG00197.1 - 7.6e-05 22.2 0.7 7.6e-05 22.2 0.7 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OAG00198.1 - 3e-90 303.3 21.3 3.7e-90 303.0 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00198.1 - 4.4e-25 88.4 23.5 5.3e-21 74.9 9.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG00198.1 - 0.00012 20.7 4.6 0.00012 20.7 4.6 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) LIP PF03583.14 OAG00199.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase Peptidase_S9 PF00326.21 OAG00199.1 - 0.031 13.7 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG00199.1 - 0.067 12.4 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 OAG00199.1 - 0.18 11.9 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein COesterase PF00135.28 OAG00201.1 - 2.9e-74 250.8 1.1 7.6e-74 249.4 1.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG00201.1 - 2.8e-09 37.1 0.3 1.2e-08 35.0 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold TBPIP_N PF15517.6 OAG00201.1 - 0.16 12.0 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 TBP-interacting protein N-terminus Putative_PNPOx PF01243.20 OAG00202.1 - 4.6e-12 46.0 0.0 1.1e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.12 OAG00202.1 - 0.051 13.7 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Abhydrolase_3 PF07859.13 OAG00204.1 - 5.2e-14 52.6 0.0 1.7e-12 47.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Gly_transf_sug PF04488.15 OAG00205.1 - 1.9e-08 34.8 0.0 4.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAG00205.1 - 0.14 11.4 0.3 0.23 10.7 0.3 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 OAG00205.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein VHS PF00790.19 OAG00206.1 - 3.9e-40 137.0 0.0 3.9e-40 137.0 0.0 1.9 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 OAG00206.1 - 1.2e-17 63.8 3.5 2.1e-17 63.0 3.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 OAG00206.1 - 2.6e-05 23.8 17.1 0.0033 17.3 1.9 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 OAG00206.1 - 2.9e-05 24.3 0.0 7.7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 GAT domain FYVE_2 PF02318.16 OAG00206.1 - 0.0019 18.4 1.0 0.004 17.4 1.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Npa1 PF11707.8 OAG00206.1 - 0.015 14.6 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal OAD_gamma PF04277.13 OAG00206.1 - 0.077 13.6 0.2 0.077 13.6 0.2 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain IBR PF01485.21 OAG00206.1 - 0.15 12.3 3.8 0.31 11.3 3.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain UCH PF00443.29 OAG00207.1 - 4.2e-56 190.3 0.0 6.6e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG00207.1 - 1.6e-16 60.8 0.0 2.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 OAG00207.1 - 0.00038 20.9 0.0 0.001 19.5 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain IPI_T4 PF11634.8 OAG00207.1 - 0.031 14.3 0.0 0.093 12.7 0.0 1.7 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 Peptidase_C98 PF15499.6 OAG00207.1 - 0.13 11.7 1.2 1.4 8.3 1.2 2.1 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Arginosuc_synth PF00764.19 OAG00208.1 - 7.7e-151 502.8 0.0 8.8e-151 502.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 OAG00208.1 - 0.0055 16.2 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Abhydrolase_3 PF07859.13 OAG00209.1 - 1.5e-24 87.0 0.0 2.3e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG00209.1 - 1.9e-07 30.3 0.0 2.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 OAG00209.1 - 0.00028 19.9 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF4386 PF14329.6 OAG00209.1 - 0.012 15.4 0.6 0.022 14.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Dynamin_M PF01031.20 OAG00210.1 - 2.7e-24 85.9 0.0 3.2e-18 66.0 0.0 2.6 3 0 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.23 OAG00210.1 - 3.6e-19 69.4 0.0 6.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OAG00210.1 - 1.1e-05 25.5 0.1 2.6e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAG00210.1 - 0.0053 16.8 0.0 0.049 13.7 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OAG00210.1 - 0.078 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 OAG00210.1 - 0.087 12.4 0.1 14 5.1 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B Tim17 PF02466.19 OAG00212.1 - 5.5e-32 110.4 6.6 7.2e-32 110.1 6.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 OAG00212.1 - 0.046 13.8 5.6 0.15 12.2 0.6 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III Lipocalin_5 PF13924.6 OAG00213.1 - 3.1e-09 36.8 0.0 3.5e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Shisa PF13908.6 OAG00215.1 - 0.00011 22.6 0.0 0.00011 22.5 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3827 PF12877.7 OAG00215.1 - 0.0035 15.8 0.2 0.0045 15.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Herpes_gE PF02480.16 OAG00215.1 - 0.0052 15.6 0.1 0.0064 15.3 0.1 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Protocadherin PF08374.11 OAG00215.1 - 0.0066 16.4 0.2 3.2 7.7 0.0 2.1 1 1 1 2 2 2 2 Protocadherin SieB PF14163.6 OAG00215.1 - 0.0087 15.6 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 1 Super-infection exclusion protein B DUF4736 PF15883.5 OAG00215.1 - 0.018 14.8 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) 7tm_2 PF00002.24 OAG00215.1 - 0.021 14.1 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) EphA2_TM PF14575.6 OAG00215.1 - 0.029 15.2 0.0 0.041 14.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PIRT PF15099.6 OAG00215.1 - 0.032 13.8 0.1 0.043 13.4 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF2207 PF09972.9 OAG00215.1 - 0.035 12.9 0.0 0.041 12.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) UPF0542 PF15086.6 OAG00215.1 - 0.042 13.8 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Phage_holin_2_3 PF16080.5 OAG00215.1 - 0.043 13.6 0.4 0.1 12.4 0.4 1.6 1 1 0 1 1 1 0 Bacteriophage holin family HP1 TMIE PF16038.5 OAG00215.1 - 0.049 13.5 0.3 0.079 12.8 0.3 1.3 1 0 0 1 1 1 0 TMIE protein TMEM154 PF15102.6 OAG00215.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Comm PF15957.5 OAG00215.1 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Commissureless DUF4245 PF14030.6 OAG00215.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Prominin PF05478.11 OAG00215.1 - 0.17 9.8 0.3 0.22 9.5 0.3 1.0 1 0 0 1 1 1 0 Prominin LapA_dom PF06305.11 OAG00215.1 - 0.31 10.9 1.1 0.52 10.2 1.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ribosomal_L33 PF00471.20 OAG00216.1 - 1.9e-05 25.0 0.0 2.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Dehydrin PF00257.19 OAG00218.1 - 0.035 14.7 0.5 0.043 14.4 0.5 1.2 1 0 0 1 1 1 0 Dehydrin KNOX1 PF03790.13 OAG00219.1 - 0.22 11.3 0.3 0.22 11.3 0.3 2.0 2 0 0 2 2 2 0 KNOX1 domain HRXXH PF13933.6 OAG00220.1 - 0.026 14.1 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family zf-MYND PF01753.18 OAG00222.1 - 8.2e-11 41.8 15.2 8.2e-11 41.8 15.2 1.6 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 OAG00222.1 - 0.0031 17.8 9.3 0.0069 16.7 9.3 1.6 1 1 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding DUF1201 PF06716.11 OAG00223.1 - 0.56 10.3 0.1 0.56 10.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Bunya_G2 PF03563.13 OAG00223.1 - 1.5 8.0 4.2 2.6 7.2 4.2 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 DUF4133 PF13571.6 OAG00223.1 - 6.7 7.1 9.9 6.2 7.2 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) DUF934 PF06073.12 OAG00224.1 - 0.045 13.7 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) GST_N_2 PF13409.6 OAG00225.1 - 1.8e-19 69.8 0.0 3.7e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG00225.1 - 1.3e-11 44.3 0.0 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG00225.1 - 2e-06 27.9 0.0 3.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG00225.1 - 0.0021 18.2 0.0 0.0052 17.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AA_permease PF00324.21 OAG00227.1 - 4.8e-101 338.7 43.6 6e-101 338.4 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG00227.1 - 4.3e-29 101.6 44.8 5.2e-29 101.3 44.8 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_10 PF13673.7 OAG00228.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG00228.1 - 0.063 13.4 0.0 3.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 OAG00229.1 - 2.5e-08 34.2 0.2 5.3e-07 29.9 0.2 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG00229.1 - 7.5e-05 23.0 0.0 0.00037 20.7 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAG00229.1 - 0.012 15.8 0.0 0.78 9.8 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Glycos_transf_3 PF00591.21 OAG00230.1 - 3.5e-37 128.4 0.0 4.9e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OAG00230.1 - 8.9e-20 70.3 0.1 2.2e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PYNP_C PF07831.13 OAG00230.1 - 2.4e-17 62.3 0.1 5.5e-17 61.2 0.1 1.7 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain ADH_N PF08240.12 OAG00231.1 - 4.4e-05 23.3 3.9 0.0072 16.2 3.9 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG00231.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Polysacc_deac_1 PF01522.21 OAG00232.1 - 1.6e-30 105.5 0.0 5.4e-30 103.8 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG00232.1 - 0.00031 20.4 0.4 0.00068 19.3 0.4 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Chitin_bind_1 PF00187.19 OAG00232.1 - 0.0012 19.2 16.2 0.0012 19.2 16.2 2.4 3 0 0 3 3 3 1 Chitin recognition protein Chitin_synth_2 PF03142.15 OAG00233.1 - 2.6e-95 320.0 1.0 4.1e-95 319.4 1.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG00233.1 - 1e-05 25.6 16.9 1.1e-05 25.5 11.7 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG00233.1 - 0.00066 19.5 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG00233.1 - 0.0011 18.9 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_hydro_20 PF00728.22 OAG00234.1 - 7.8e-44 150.5 1.7 1.9e-42 146.0 1.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Aldedh PF00171.22 OAG00235.1 - 8.7e-77 258.6 0.0 1.1e-76 258.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.22 OAG00236.1 - 3.9e-59 200.6 0.0 4.5e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IRK_N PF08466.10 OAG00236.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal TRI12 PF06609.13 OAG00238.1 - 1.6e-40 139.1 33.4 3.5e-29 101.7 21.4 2.5 1 1 2 3 3 3 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG00238.1 - 7.3e-08 31.7 64.8 7.3e-08 31.7 64.8 3.1 2 2 0 2 2 2 1 Major Facilitator Superfamily TNFR_16_TM PF18422.1 OAG00238.1 - 0.74 9.8 2.7 2.5 8.1 2.7 1.9 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain F-box-like_2 PF13013.6 OAG00239.1 - 0.054 13.5 0.0 0.68 9.9 0.0 2.3 1 1 0 1 1 1 0 F-box-like domain DUF4677 PF15726.5 OAG00240.1 - 0.061 13.5 0.5 0.11 12.7 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) LOH1CR12 PF10158.9 OAG00240.1 - 0.15 12.1 2.0 0.19 11.8 0.5 1.8 1 1 1 2 2 2 0 Tumour suppressor protein Snapin_Pallidin PF14712.6 OAG00240.1 - 0.23 11.9 5.5 1.8 9.0 0.2 2.7 1 1 2 3 3 3 0 Snapin/Pallidin DUF4559 PF15112.6 OAG00240.1 - 0.28 10.8 2.2 0.39 10.3 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF16 PF01519.16 OAG00240.1 - 0.37 11.3 4.5 10 6.6 0.9 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 Cor1 PF04803.12 OAG00240.1 - 0.43 10.8 2.7 0.29 11.3 0.3 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region COG2 PF06148.11 OAG00240.1 - 0.7 10.0 5.0 1.5 8.9 0.7 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.9 OAG00240.1 - 0.79 10.1 7.3 2 8.8 1.9 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 OAG00240.1 - 1.1 9.3 8.3 0.42 10.7 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OAG00240.1 - 2.6 8.2 7.7 7.2 6.8 6.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family THOC7 PF05615.13 OAG00240.1 - 5.1 7.4 7.1 18 5.6 0.1 2.2 1 1 0 2 2 2 0 Tho complex subunit 7 NAD_binding_10 PF13460.6 OAG00241.1 - 8e-19 68.2 0.0 1.5e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG00241.1 - 9.1e-18 64.7 0.0 1.2e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG00241.1 - 1.4e-05 25.4 0.1 4.7e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG00241.1 - 0.0004 20.8 0.0 0.0014 19.1 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG00241.1 - 0.027 13.9 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OAG00241.1 - 0.032 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PALP PF00291.25 OAG00241.1 - 0.063 12.7 0.2 0.21 10.9 0.2 1.7 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 OAG00241.1 - 0.11 11.8 0.1 0.39 10.0 0.1 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DXP_reductoisom PF02670.16 OAG00241.1 - 0.14 12.9 0.2 0.34 11.6 0.2 1.7 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MFS_1 PF07690.16 OAG00244.1 - 7.6e-50 169.8 45.3 7.6e-50 169.8 45.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG00244.1 - 1.3e-13 50.2 11.9 1.3e-13 50.2 11.9 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG00244.1 - 1.2e-10 40.9 3.3 1.2e-10 40.9 3.3 3.5 2 2 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 OAG00244.1 - 0.34 9.2 19.9 0.1 10.9 1.1 3.4 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Opy2 PF09463.10 OAG00245.1 - 3.1e-05 24.2 22.9 5.1e-05 23.5 22.9 1.3 1 0 0 1 1 1 1 Opy2 protein Mid2 PF04478.12 OAG00245.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor HMG14_17 PF01101.18 OAG00245.1 - 2.3 9.3 6.1 3.3 8.7 1.1 2.7 2 0 0 2 2 2 0 HMG14 and HMG17 zf-RING_2 PF13639.6 OAG00247.1 - 5.2e-06 26.7 6.5 0.00011 22.4 2.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OAG00247.1 - 1.1e-05 25.1 1.2 0.0093 15.7 0.2 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-rbx1 PF12678.7 OAG00247.1 - 1.2e-05 25.5 1.3 1.2e-05 25.5 1.3 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG00247.1 - 0.0016 18.4 2.1 0.0016 18.4 2.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG00247.1 - 0.0034 17.4 3.3 0.0073 16.3 0.2 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG00247.1 - 0.0035 17.2 5.9 0.004 17.0 2.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG00247.1 - 0.0053 16.8 3.2 0.022 14.8 1.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OAG00247.1 - 0.073 12.9 8.1 0.083 12.8 3.8 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG00247.1 - 0.27 11.1 8.2 0.061 13.2 4.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 OAG00247.1 - 0.53 10.2 5.2 0.19 11.6 1.8 2.0 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.8 OAG00247.1 - 1.1 9.4 4.9 1.2 9.3 1.2 2.5 2 0 0 2 2 2 0 FANCL C-terminal domain Bac_luciferase PF00296.20 OAG00248.1 - 1.5e-56 192.1 0.8 2.1e-56 191.7 0.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.17 OAG00249.1 - 4e-21 75.4 29.9 7.2e-21 74.5 29.9 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family F_bP_aldolase PF01116.20 OAG00250.1 - 3.7e-76 256.3 0.0 4.1e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CobS PF02654.15 OAG00250.1 - 0.072 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase Fungal_trans_2 PF11951.8 OAG00251.1 - 2.3e-13 49.7 0.8 8.8e-12 44.5 0.5 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG00251.1 - 3e-07 30.4 13.4 3e-07 30.4 13.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-MYST PF17772.1 OAG00251.1 - 0.032 13.8 0.1 0.094 12.3 0.1 1.7 1 0 0 1 1 1 0 MYST family zinc finger domain adh_short_C2 PF13561.6 OAG00252.1 - 5e-53 180.1 0.0 6.4e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG00252.1 - 1.2e-47 162.0 0.1 1.4e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG00252.1 - 1.4e-09 38.1 0.1 2.5e-09 37.3 0.1 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG00252.1 - 0.00014 21.2 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG00252.1 - 0.0069 15.9 0.1 0.025 14.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG00252.1 - 0.0073 15.3 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.12 OAG00252.1 - 0.14 12.9 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 OAG00253.1 - 2.1e-38 132.2 34.7 2.1e-38 132.2 34.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5408 PF17402.2 OAG00253.1 - 0.38 10.7 0.0 0.38 10.7 0.0 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF5408) p450 PF00067.22 OAG00254.1 - 3.8e-19 68.8 1.3 3.9e-08 32.5 0.1 4.2 2 1 1 4 4 4 3 Cytochrome P450 Gly_rich PF12810.7 OAG00255.1 - 0.0024 17.9 51.0 0.0024 17.9 51.0 4.1 1 1 2 3 3 3 1 Glycine rich protein Dicty_REP PF05086.12 OAG00255.1 - 3.7 5.4 15.2 6.4 4.6 15.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mito_fiss_reg PF05308.11 OAG00255.1 - 4.9 7.2 5.1 7.7 6.5 5.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3494 PF11999.8 OAG00256.1 - 1.2e-20 74.0 2.7 1.2e-20 74.0 2.7 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3494) Pox_A12 PF04651.13 OAG00256.1 - 0.076 13.1 0.8 0.14 12.2 0.8 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein APG6_N PF17675.1 OAG00257.1 - 0.031 14.8 0.9 0.038 14.5 0.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2205 PF10224.9 OAG00257.1 - 0.073 13.1 1.4 0.16 12.0 1.4 1.5 1 0 0 1 1 1 0 Short coiled-coil protein YabA PF06156.13 OAG00257.1 - 0.088 13.5 1.4 0.12 13.0 1.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA ketoacyl-synt PF00109.26 OAG00258.1 - 2.4e-65 220.7 0.0 7.6e-65 219.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG00258.1 - 4.8e-55 187.3 0.1 7.7e-55 186.6 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG00258.1 - 1.8e-54 185.0 0.0 2.8e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAG00258.1 - 6e-49 166.4 0.0 5.6e-48 163.2 0.0 2.4 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 OAG00258.1 - 4.8e-40 136.2 0.1 1.6e-39 134.6 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAG00258.1 - 5.7e-17 62.2 0.0 1.7e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 OAG00258.1 - 8.8e-14 51.6 0.1 3e-13 49.9 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG00258.1 - 3.3e-12 47.6 0.0 1.2e-10 42.5 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG00258.1 - 2.8e-08 33.5 0.1 1.1e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00258.1 - 4.7e-06 26.3 0.2 2.9e-05 23.7 0.0 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 OAG00258.1 - 7.4e-06 25.8 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 OAG00258.1 - 0.00058 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OAG00259.1 - 1.7e-39 135.3 0.2 2.9e-39 134.5 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00259.1 - 2.5e-30 105.8 0.0 3.2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00259.1 - 6e-05 23.0 0.4 0.00012 22.1 0.4 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG00259.1 - 0.0049 16.4 0.1 0.0075 15.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.22 OAG00260.1 - 9.3e-46 156.5 0.0 1.4e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SNARE_assoc PF09335.11 OAG00260.1 - 0.099 13.1 1.1 0.4 11.2 1.1 2.1 1 0 0 1 1 1 0 SNARE associated Golgi protein Zn_clus PF00172.18 OAG00261.1 - 2.2e-08 34.1 10.1 2.6e-08 33.9 10.1 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 OAG00261.1 - 0.12 12.7 12.8 0.22 11.9 12.8 1.5 1 1 0 1 1 1 0 Opy2 protein Cupin_2 PF07883.11 OAG00262.1 - 3.5e-07 29.8 0.0 1.8e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Auxin_BP PF02041.16 OAG00262.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.5 1 1 0 1 1 1 0 Auxin binding protein MFS_1 PF07690.16 OAG00263.1 - 9.6e-15 54.3 55.9 8.1e-07 28.3 23.9 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 OAG00263.1 - 7.2e-06 24.7 16.6 1.1e-05 24.1 16.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG00265.1 - 1.3e-30 106.6 35.3 2.2e-29 102.5 20.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF169 PF02596.15 OAG00266.1 - 0.061 13.2 0.1 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 Herpes_UL25 PF01499.16 OAG00267.1 - 0.1 11.1 2.6 0.13 10.7 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family FUSC PF04632.12 OAG00267.1 - 5.3 5.4 9.0 7.1 5.0 9.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAD_binding_4 PF01565.23 OAG00268.1 - 6.3e-28 97.3 0.0 1.1e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG00268.1 - 2.4e-07 30.7 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain GMC_oxred_N PF00732.19 OAG00270.1 - 1.9e-30 106.2 0.0 4.7e-29 101.7 0.0 2.4 1 1 1 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG00270.1 - 9.3e-22 78.1 0.0 3.1e-21 76.4 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase PPTA PF01239.22 OAG00271.1 - 6.7e-41 136.9 20.1 1.1e-09 37.7 0.4 6.3 6 0 0 6 6 6 6 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 OAG00271.1 - 0.13 12.7 0.8 4.5 7.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PALP PF00291.25 OAG00272.1 - 2.9e-65 220.6 0.7 3.6e-65 220.3 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M19 PF01244.21 OAG00273.1 - 3.5e-101 338.6 0.0 4.1e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 OAG00273.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Ilm1 PF10311.9 OAG00274.1 - 3.2e-54 183.0 0.1 3.7e-54 182.8 0.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 TctB PF07331.11 OAG00274.1 - 0.12 12.6 7.9 0.21 11.8 7.8 1.5 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Ldh_1_C PF02866.18 OAG00275.1 - 1.4e-20 73.9 0.0 1.8e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAG00275.1 - 3e-05 24.1 0.0 5.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Beta_helix PF13229.6 OAG00276.1 - 3.3e-10 40.0 15.8 1.3e-08 34.8 12.3 2.3 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 OAG00276.1 - 4.2e-08 32.5 0.1 1.1e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Chondroitinase B DUF1565 PF07602.11 OAG00276.1 - 0.0048 16.3 0.5 0.0048 16.3 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) adh_short PF00106.25 OAG00277.1 - 1.4e-41 142.1 0.0 2e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00277.1 - 3.9e-31 108.4 0.0 5.2e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00277.1 - 8.2e-11 42.1 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG00277.1 - 0.00025 20.3 0.0 0.00031 20.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 OAG00277.1 - 0.0017 17.8 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Nodulin_late PF07127.11 OAG00281.1 - 0.0059 16.9 6.5 0.039 14.3 0.5 2.2 2 0 0 2 2 2 2 Late nodulin protein Gamma-thionin PF00304.20 OAG00281.1 - 0.064 13.5 18.0 0.95 9.8 5.4 2.4 2 0 0 2 2 2 0 Gamma-thionin family Squash PF00299.18 OAG00281.1 - 1.6 8.8 17.0 0.39 10.8 3.8 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor RAMP4 PF06624.12 OAG00286.1 - 7.3e-15 54.8 0.0 8e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Mei5 PF10376.9 OAG00286.1 - 0.19 11.5 0.2 0.23 11.3 0.2 1.0 1 0 0 1 1 1 0 Double-strand recombination repair protein Adaptin_N PF01602.20 OAG00287.1 - 5.2e-77 259.6 0.0 2.1e-76 257.6 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 OAG00287.1 - 0.00013 22.4 5.6 4.5 7.9 0.0 4.9 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 OAG00287.1 - 0.00027 21.3 0.9 0.22 11.9 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 OAG00287.1 - 0.0026 17.8 0.0 0.065 13.3 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG00287.1 - 0.0063 16.7 0.1 11 6.6 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat DUF773 PF05600.12 OAG00287.1 - 1.5 7.4 6.1 2.4 6.8 6.1 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Ead_Ea22 PF13935.6 OAG00287.1 - 3.2 8.4 6.2 7.6 7.2 6.2 1.6 1 0 0 1 1 1 0 Ead/Ea22-like protein TPR_19 PF14559.6 OAG00288.1 - 4.4e-11 43.1 1.4 5.8e-05 23.5 0.0 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG00288.1 - 1.3e-08 34.3 1.7 0.0031 17.5 0.1 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG00288.1 - 2e-07 31.3 7.8 0.0016 19.1 0.0 5.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG00288.1 - 2.6e-06 28.0 4.3 0.073 13.7 0.1 4.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAG00288.1 - 5.1e-06 26.5 0.0 0.058 13.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG00288.1 - 1.4e-05 24.6 1.2 1.8 8.3 0.0 5.4 5 1 1 6 6 6 1 TPR repeat TPR_6 PF13174.6 OAG00288.1 - 7.5e-05 23.1 0.3 2.5 8.9 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OAG00288.1 - 9.6e-05 22.4 0.1 0.058 13.3 0.0 2.5 2 0 0 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 OAG00288.1 - 0.00019 21.5 0.5 0.001 19.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG00288.1 - 0.00044 20.0 0.7 8.1 6.5 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 OAG00288.1 - 0.00044 20.7 1.3 0.033 14.6 0.0 2.7 1 1 2 3 3 3 2 Bacterial transcriptional activator domain TPR_8 PF13181.6 OAG00288.1 - 0.0046 17.1 0.4 3.9 7.9 0.0 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 OAG00288.1 - 0.074 12.0 0.1 0.095 11.7 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 OAG00288.1 - 0.13 12.6 4.9 9.6 6.6 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_L_2 PF13656.6 OAG00290.1 - 8.7e-23 79.9 0.0 1.6e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAG00290.1 - 2.6e-06 26.7 0.0 5.4e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EF-hand_4 PF12763.7 OAG00291.1 - 9e-27 93.1 0.0 4e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 OAG00291.1 - 6.7e-09 35.3 1.2 6.7e-09 35.3 1.2 2.6 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.11 OAG00291.1 - 8.7e-05 22.9 63.8 0.00081 19.8 24.3 7.5 5 2 2 7 7 7 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 OAG00291.1 - 0.00012 22.5 0.0 0.089 13.3 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair E3_binding PF02817.17 OAG00291.1 - 0.058 13.7 1.6 0.1 13.0 0.1 2.2 2 0 0 2 2 2 0 e3 binding domain CENP-Q PF13094.6 OAG00292.1 - 0.0014 18.9 0.4 0.0015 18.8 0.4 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CLZ PF16526.5 OAG00292.1 - 0.004 17.5 0.1 0.0049 17.2 0.1 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IF-2B PF01008.17 OAG00293.1 - 4.7e-72 242.6 0.5 5.6e-72 242.3 0.5 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Aldo_ket_red PF00248.21 OAG00294.1 - 1.3e-45 155.9 0.0 5.2e-34 117.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family P3A PF08727.11 OAG00294.1 - 0.14 11.5 2.5 0.63 9.5 1.1 2.6 3 0 0 3 3 3 0 Poliovirus 3A protein like ABC2_membrane PF01061.24 OAG00295.1 - 2.3e-84 282.0 57.8 2.2e-45 154.7 14.3 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG00295.1 - 3.7e-37 127.9 0.0 3.8e-18 66.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG00295.1 - 3.6e-31 106.9 2.3 1.6e-24 85.6 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG00295.1 - 5.1e-18 65.5 0.9 5.1e-18 65.5 0.9 2.3 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAG00295.1 - 2.1e-07 31.5 0.1 0.0034 17.8 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG00295.1 - 5.6e-07 29.6 0.2 0.00017 21.5 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 OAG00295.1 - 6.7e-07 29.9 0.4 0.00078 20.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 OAG00295.1 - 9e-07 29.0 0.0 0.022 14.6 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAG00295.1 - 1.9e-06 28.2 0.0 0.016 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAG00295.1 - 1.7e-05 25.0 0.1 0.016 15.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 OAG00295.1 - 7.2e-05 22.8 0.3 0.029 14.5 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 OAG00295.1 - 9.9e-05 22.0 0.1 0.0067 16.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 OAG00295.1 - 0.00012 21.8 0.2 0.22 11.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 OAG00295.1 - 0.00072 19.8 1.7 0.0073 16.6 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 OAG00295.1 - 0.0012 18.6 0.1 1.4 8.6 0.2 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 OAG00295.1 - 0.0014 17.8 10.8 0.0014 17.8 10.8 2.6 2 0 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 OAG00295.1 - 0.0037 16.7 0.1 0.14 11.5 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 OAG00295.1 - 0.0088 16.0 0.3 0.55 10.1 0.2 2.4 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 OAG00295.1 - 0.0089 16.5 0.6 0.19 12.2 0.3 2.6 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 OAG00295.1 - 0.011 15.6 0.1 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 OAG00295.1 - 0.013 15.4 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 OAG00295.1 - 0.013 15.1 0.1 0.4 10.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG00295.1 - 0.015 15.0 0.0 0.32 10.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 OAG00295.1 - 0.023 14.0 0.1 0.3 10.3 0.1 2.3 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 OAG00295.1 - 0.052 12.8 0.5 1.2 8.4 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 OAG00295.1 - 0.053 13.6 0.4 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 OAG00295.1 - 0.082 12.4 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 OAG00295.1 - 0.083 12.2 1.5 4.2 6.6 0.3 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family T2SSE PF00437.20 OAG00295.1 - 0.094 11.8 0.1 1.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 OAG00295.1 - 0.1 11.7 0.5 3.5 6.7 0.3 2.4 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 OAG00295.1 - 0.11 12.2 0.7 1.8 8.3 0.3 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 OAG00295.1 - 0.13 12.3 0.2 0.76 9.8 0.2 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OAG00295.1 - 0.15 12.3 0.1 2.1 8.6 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 OAG00296.1 - 7.2e-30 104.1 26.3 1.2e-29 103.4 26.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG00296.1 - 6.1e-10 38.5 0.5 6.1e-10 38.5 0.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter Gly-zipper_Omp PF13488.6 OAG00296.1 - 0.95 9.5 4.2 0.97 9.5 0.9 2.8 2 1 0 2 2 2 0 Glycine zipper RRS1 PF04939.12 OAG00297.1 - 1.1e-59 200.9 4.6 1.4e-59 200.6 4.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 OAG00298.1 - 2.2e-99 332.6 0.0 3.2e-99 332.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NMO PF03060.15 OAG00299.1 - 2.3e-30 106.1 3.2 7.6e-24 84.7 0.7 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 OAG00299.1 - 2.1e-07 30.3 1.8 3.1e-05 23.1 1.8 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG00299.1 - 6e-05 22.2 1.2 7.9e-05 21.8 1.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG00299.1 - 0.00088 18.5 0.3 0.0014 17.8 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF3443 PF11925.8 OAG00299.1 - 0.039 12.8 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) HSP20 PF00011.21 OAG00300.1 - 3.1e-21 75.4 0.5 1.7e-14 53.8 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG00300.1 - 5.5e-06 25.9 0.1 4.3e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HisG PF01634.18 OAG00302.1 - 2e-56 190.4 0.3 3.1e-56 189.8 0.3 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OAG00302.1 - 8e-29 99.6 0.7 2e-28 98.3 0.3 1.9 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 OAG00302.1 - 0.0021 18.1 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 NMT1/THI5 like Ribosomal_S28e PF01200.18 OAG00304.1 - 1.8e-30 104.7 1.9 2e-30 104.6 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MFS_1 PF07690.16 OAG00305.1 - 1.4e-47 162.4 42.7 1.4e-47 162.4 42.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG00305.1 - 3.7e-18 65.6 1.9 3.7e-18 65.6 1.9 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG00305.1 - 3.5e-05 23.3 10.2 3.5e-05 23.3 10.2 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF3543 PF12063.8 OAG00306.1 - 1.3e-81 273.7 0.0 2.2e-81 272.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 OAG00306.1 - 7.5e-60 202.5 0.0 1.5e-59 201.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00306.1 - 4.5e-42 144.1 0.0 9.6e-42 143.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Complex1_LYR PF05347.15 OAG00307.1 - 2.7e-19 68.9 3.0 3.2e-19 68.7 3.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG00307.1 - 2.3e-06 28.3 0.8 2.7e-06 28.0 0.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OAG00307.1 - 0.0013 19.3 3.0 0.017 15.7 0.2 2.1 1 1 1 2 2 2 2 Complex1_LYR-like DAHP_synth_1 PF00793.20 OAG00310.1 - 1.2e-102 342.5 0.1 1.6e-102 342.1 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AP_endonuc_2 PF01261.24 OAG00311.1 - 4.5e-33 114.5 0.0 6.6e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SBP_bac_8 PF13416.6 OAG00311.1 - 0.035 13.9 0.0 0.17 11.6 0.0 2.0 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein Tagatose_6_P_K PF08013.11 OAG00312.1 - 0.06 12.0 0.0 0.078 11.6 0.0 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Abhydrolase_1 PF00561.20 OAG00313.1 - 2.2e-06 27.5 0.0 2.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG00313.1 - 7.3e-05 23.5 0.0 8.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG00313.1 - 0.0017 17.6 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DNA_pol_E_B PF04042.16 OAG00315.1 - 8e-44 149.5 0.0 1.2e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OAG00315.1 - 1.5e-38 131.9 0.0 2.2e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain ADH_zinc_N PF00107.26 OAG00316.1 - 1.1e-22 80.4 1.6 1.1e-22 80.4 1.6 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG00316.1 - 4.9e-17 61.8 3.2 4.9e-17 61.8 3.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG00316.1 - 1.7e-05 25.9 0.4 3.1e-05 25.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.8 OAG00317.1 - 1e-11 44.3 0.2 2.9e-09 36.2 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG00317.1 - 8.2e-10 38.6 9.4 1.5e-09 37.8 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 OAG00317.1 - 2.4 8.0 7.0 0.46 10.3 2.6 2.0 1 1 1 2 2 2 0 Integrin plexin domain Glyco_hydro_3_C PF01915.22 OAG00318.1 - 1.5e-55 188.4 0.0 4.8e-55 186.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG00318.1 - 3e-52 178.0 0.0 4.9e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG00318.1 - 2.4e-17 62.8 0.0 4.8e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAG00318.1 - 1.8e-07 31.1 0.0 4.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Far-17a_AIG1 PF04750.14 OAG00319.1 - 8.4e-48 162.4 6.5 9.6e-48 162.2 6.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein zf-SCNM1 PF15803.5 OAG00320.1 - 0.14 11.8 1.1 0.28 10.8 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 Prenyltrans PF00432.21 OAG00321.1 - 3.2e-49 164.3 9.9 3.7e-11 42.6 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat RhoGAP PF00620.27 OAG00322.1 - 3.2e-30 105.0 0.0 5.1e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1952 PF09189.10 OAG00322.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) hDGE_amylase PF14701.6 OAG00323.1 - 8e-182 605.2 0.0 1e-181 604.8 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OAG00323.1 - 2.6e-119 398.6 0.0 4.1e-119 397.9 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OAG00323.1 - 1.1e-87 293.9 0.0 1.8e-87 293.2 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 OAG00323.1 - 1.7e-27 95.4 0.1 4.4e-27 94.0 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 OAG00323.1 - 5.5e-05 22.9 0.1 0.00052 19.7 0.1 2.1 2 0 0 2 2 2 1 Alpha amylase, catalytic domain SNF2_N PF00176.23 OAG00324.1 - 9.9e-67 225.1 0.0 1.4e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAG00324.1 - 6.6e-16 58.0 0.0 1.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAG00324.1 - 2.9e-14 53.4 0.0 1.8e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 OAG00324.1 - 3.8e-11 42.6 11.8 8.3e-11 41.5 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG00324.1 - 6.1e-11 42.0 8.7 1.4e-10 40.9 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG00324.1 - 4.1e-09 36.6 10.7 9.7e-09 35.4 10.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG00324.1 - 7.3e-09 35.4 12.5 1.8e-08 34.1 12.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG00324.1 - 3.7e-08 33.2 9.5 7.8e-08 32.1 9.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG00324.1 - 5.3e-08 32.8 9.8 7e-08 32.4 8.7 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAG00324.1 - 4e-07 30.1 11.0 9.1e-07 28.9 11.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAG00324.1 - 1.6e-06 28.3 6.1 4.4e-06 26.9 6.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain ResIII PF04851.15 OAG00324.1 - 4.6e-06 26.7 0.0 9.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 OAG00324.1 - 6.7e-06 25.9 9.8 6.9e-06 25.8 8.4 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OAG00324.1 - 0.0053 16.6 8.6 0.01 15.7 7.3 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OAG00324.1 - 0.0079 16.2 5.0 0.021 14.9 4.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OAG00324.1 - 0.014 15.2 4.1 0.033 14.1 4.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 OAG00324.1 - 0.023 14.5 9.0 0.46 10.3 9.9 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OAG00324.1 - 0.21 11.4 5.6 0.62 9.9 5.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 OAG00324.1 - 0.34 11.1 6.4 0.83 9.8 6.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 OAG00324.1 - 0.51 10.2 3.3 12 5.8 0.0 2.9 3 0 0 3 3 2 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.12 OAG00324.1 - 0.86 9.6 8.8 0.44 10.6 6.2 1.9 2 0 0 2 2 1 0 zinc-ribbons DZR PF12773.7 OAG00324.1 - 2.1 8.5 5.1 4.7 7.3 5.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon TFIIB PF00382.19 OAG00325.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Peptidase_C48 PF02902.19 OAG00326.1 - 1.7e-12 47.7 0.3 6.9e-12 45.7 0.3 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain OSTbeta PF15048.6 OAG00326.1 - 0.087 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein zf-LYAR PF08790.11 OAG00327.1 - 3.8e-14 52.3 4.4 3.8e-14 52.3 4.4 2.8 4 0 0 4 4 4 1 LYAR-type C2HC zinc finger Evr1_Alr PF04777.13 OAG00328.1 - 6.9e-27 93.9 0.1 8.6e-27 93.5 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Aminotran_4 PF01063.19 OAG00329.1 - 4.1e-24 85.7 0.0 5.8e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 OAG00330.1 - 7.4e-75 252.4 0.0 9.3e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 OAG00332.1 - 2.7e-74 249.9 0.0 4.9e-74 249.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00332.1 - 3.4e-36 124.8 0.0 5.3e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAG00332.1 - 2.8e-16 59.6 0.0 6.1e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 OAG00332.1 - 7.6e-10 38.6 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG00332.1 - 2.5e-07 29.8 0.1 5.6e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 OAG00332.1 - 6.6e-06 26.4 0.0 2.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 OAG00332.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OAG00332.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ThiS PF02597.20 OAG00332.1 - 0.16 12.7 0.0 0.49 11.1 0.0 1.8 1 0 0 1 1 1 0 ThiS family DUF2961 PF11175.8 OAG00332.1 - 0.16 11.6 0.1 12 5.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2961) Autophagy_act_C PF03987.15 OAG00333.1 - 6.9e-14 52.2 0.7 1.6e-13 51.0 0.7 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DCB PF16213.5 OAG00334.1 - 0.19 11.4 0.8 0.37 10.4 0.8 1.5 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 MFS_1 PF07690.16 OAG00335.1 - 5.1e-33 114.4 43.6 5.1e-33 114.4 43.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily KicB PF03882.14 OAG00335.1 - 0.15 12.2 0.1 0.42 10.8 0.1 1.7 1 0 0 1 1 1 0 MukF winged-helix domain MFS_1 PF07690.16 OAG00336.1 - 6.1e-33 114.2 28.4 9e-33 113.6 28.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 OAG00337.1 - 1.7e-15 57.1 11.8 0.00018 22.2 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG00337.1 - 1.8e-07 31.4 0.1 0.046 14.0 0.0 4.6 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAG00337.1 - 0.02 14.8 0.0 4.4 7.4 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat IGR PF09597.10 OAG00338.1 - 7.8e-26 90.0 0.0 1.6e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 IGR protein motif Zn_clus PF00172.18 OAG00339.1 - 2.1e-05 24.5 7.5 4.6e-05 23.5 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG00339.1 - 0.0036 16.4 0.0 0.0089 15.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain CLZ PF16526.5 OAG00339.1 - 0.15 12.4 3.5 2.5 8.5 0.1 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Apolipoprotein PF01442.18 OAG00339.1 - 0.52 10.2 2.5 7.1 6.5 0.2 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain HemY_N PF07219.13 OAG00340.1 - 0.25 11.6 2.1 0.59 10.4 2.1 1.6 1 0 0 1 1 1 0 HemY protein N-terminus Acetyltransf_7 PF13508.7 OAG00341.1 - 0.0074 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG00341.1 - 0.013 15.8 0.0 0.016 15.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family AIG2_2 PF13772.6 OAG00342.1 - 0.00023 21.5 0.0 0.00054 20.3 0.0 1.7 1 1 0 1 1 1 1 AIG2-like family p450 PF00067.22 OAG00343.1 - 9.6e-49 166.4 0.0 1.3e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HGTP_anticodon2 PF12745.7 OAG00344.1 - 0.055 13.0 0.4 0.055 13.0 0.4 2.0 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Mitoc_mL59 PF18126.1 OAG00345.1 - 9.6e-44 148.8 1.1 1.2e-43 148.4 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Drf_FH1 PF06346.12 OAG00345.1 - 0.055 13.2 5.6 0.077 12.7 5.6 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 Proteasome PF00227.26 OAG00346.1 - 5.5e-40 136.9 0.0 6.7e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.29 OAG00347.1 - 2.7e-47 160.8 0.0 6.4e-47 159.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG00347.1 - 1.3e-27 96.3 0.0 7.3e-27 93.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG00347.1 - 0.001 19.1 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 OAG00347.1 - 0.0085 16.6 7.4 0.0085 16.6 7.4 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2986) PRAI PF00697.22 OAG00347.1 - 0.035 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CENP-Q PF13094.6 OAG00349.1 - 0.06 13.6 0.5 0.06 13.6 0.5 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ATP_sub_h PF10775.9 OAG00349.1 - 1.1 9.3 5.7 1.3 9.1 2.6 2.4 1 1 1 2 2 2 0 ATP synthase complex subunit h UPF0029 PF01205.19 OAG00350.1 - 2.6e-22 79.2 0.8 1.6e-21 76.6 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized protein family UPF0029 Ribosomal_L34 PF00468.17 OAG00351.1 - 9.6e-19 67.1 7.0 1.4e-18 66.6 7.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 GHMP_kinases_N PF00288.26 OAG00353.1 - 2.9e-13 49.8 0.1 9e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG00353.1 - 2.8e-08 34.0 0.0 9.2e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OAG00353.1 - 0.0084 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature G-patch PF01585.23 OAG00354.1 - 1.4e-05 24.9 0.0 8.6e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 G-patch domain Mitofilin PF09731.9 OAG00354.1 - 0.65 8.8 32.7 0.92 8.3 32.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GREB1 PF15782.5 OAG00354.1 - 5.2 4.0 17.9 6.6 3.7 17.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PBP PF01161.20 OAG00356.1 - 4.5e-13 49.7 0.2 5.6e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein tRNA-synt_1d PF00750.19 OAG00357.1 - 5.7e-61 206.4 2.0 1.9e-60 204.7 2.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAG00357.1 - 1.9e-13 50.7 0.0 4.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain PHTB1_C PF14728.6 OAG00358.1 - 0.11 11.6 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 PTHB1 C-terminus DHR10 PF18595.1 OAG00358.1 - 9.1 6.4 10.4 0.8 9.8 3.7 2.5 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain HTH_Tnp_Tc5 PF03221.16 OAG00360.1 - 3e-08 33.6 0.4 3.9e-08 33.2 0.4 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CDC37_M PF08565.11 OAG00360.1 - 0.028 14.3 0.3 0.031 14.2 0.3 1.1 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain YGGT PF02325.17 OAG00360.1 - 0.055 13.9 0.0 0.063 13.7 0.0 1.3 1 1 0 1 1 1 0 YGGT family Cu PF17563.2 OAG00360.1 - 0.16 12.2 0.4 0.23 11.7 0.4 1.4 1 1 0 1 1 1 0 Cupiennin M20_dimer PF07687.14 OAG00361.1 - 6.3e-20 71.1 0.0 1.3e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAG00361.1 - 2.7e-19 69.7 0.0 3.5e-18 66.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OAG00361.1 - 5e-05 23.1 0.0 0.00012 21.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Pectate_lyase PF03211.13 OAG00362.1 - 2.5e-84 281.9 8.2 3.1e-84 281.6 8.2 1.1 1 0 0 1 1 1 1 Pectate lyase Iron_permease PF04120.12 OAG00363.1 - 0.66 9.7 4.3 0.83 9.4 4.3 1.4 1 1 0 1 1 1 0 Low affinity iron permease Methyltransf_12 PF08242.12 OAG00365.1 - 2e-14 54.1 0.0 7.2e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG00365.1 - 6.7e-13 49.2 0.0 2e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG00365.1 - 1.6e-11 44.3 0.0 3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG00365.1 - 6.6e-10 39.5 0.0 2.1e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG00365.1 - 1.1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG00365.1 - 6.9e-06 25.6 0.0 2e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 OAG00365.1 - 0.0014 19.6 0.0 0.0028 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OAG00365.1 - 0.046 13.6 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF3419 PF11899.8 OAG00365.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Polyketide_cyc PF03364.20 OAG00366.1 - 1.1e-20 74.2 0.1 7.4e-20 71.5 0.1 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OAG00366.1 - 0.0014 18.9 0.3 0.015 15.6 0.3 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DnaJ PF00226.31 OAG00367.1 - 8.4e-21 73.9 5.2 1.3e-20 73.2 5.2 1.3 1 0 0 1 1 1 1 DnaJ domain PRA1 PF03208.19 OAG00369.1 - 8.1e-39 132.5 0.7 9.9e-39 132.2 0.7 1.1 1 0 0 1 1 1 1 PRA1 family protein Renin_r PF07850.14 OAG00369.1 - 0.0032 18.0 0.2 0.0058 17.2 0.2 1.4 1 0 0 1 1 1 1 Renin receptor-like protein DUF2207 PF09972.9 OAG00369.1 - 0.11 11.2 1.1 0.13 11.0 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4212 PF13937.6 OAG00369.1 - 0.67 10.4 5.1 1.7 9.1 5.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4212) DnaJ PF00226.31 OAG00370.1 - 4.8e-11 42.6 1.9 7.7e-10 38.8 1.9 2.6 1 1 0 1 1 1 1 DnaJ domain Herpes_gE PF02480.16 OAG00371.1 - 0.00072 18.4 0.0 0.001 17.9 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 OAG00371.1 - 0.0087 16.0 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family SSP160 PF06933.11 OAG00371.1 - 0.0087 14.3 3.3 0.012 13.9 3.3 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 LapA_dom PF06305.11 OAG00371.1 - 0.018 14.8 0.8 0.041 13.7 0.8 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 OAG00371.1 - 0.019 14.4 0.1 0.044 13.2 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4690 PF15756.5 OAG00371.1 - 0.022 15.3 0.9 0.041 14.5 0.9 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage TMEM51 PF15345.6 OAG00371.1 - 0.024 14.5 0.2 0.035 13.9 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Trp_oprn_chp PF09534.10 OAG00371.1 - 0.027 14.3 0.7 0.043 13.6 0.7 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2613 PF11021.8 OAG00371.1 - 0.051 13.7 0.3 0.051 13.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Nitrate_red_gam PF02665.14 OAG00371.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5305 PF17231.2 OAG00371.1 - 0.17 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) adh_short_C2 PF13561.6 OAG00372.1 - 2.5e-59 200.7 1.6 6.4e-59 199.4 1.6 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG00372.1 - 6.8e-49 166.0 0.2 1.5e-48 164.9 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG00372.1 - 4.8e-08 33.1 0.6 1.6e-07 31.4 0.6 1.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG00372.1 - 6.9e-05 22.4 0.1 0.00016 21.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HET PF06985.11 OAG00373.1 - 8.9e-33 113.7 3.8 1.6e-32 112.9 3.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Oxidored_q2 PF00420.24 OAG00374.1 - 0.011 15.4 0.8 0.011 15.4 0.8 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PMP1_2 PF08114.11 OAG00374.1 - 0.021 14.6 1.2 0.026 14.3 1.2 1.1 1 0 0 1 1 1 0 ATPase proteolipid family DDDD PF10161.9 OAG00374.1 - 0.043 13.6 0.2 0.053 13.3 0.2 1.3 1 0 0 1 1 1 0 Putative mitochondrial precursor protein TM_helix PF05552.12 OAG00374.1 - 0.07 13.1 4.4 0.12 12.3 4.4 1.4 1 0 0 1 1 1 0 Conserved TM helix LapA_dom PF06305.11 OAG00374.1 - 1.2 9.0 4.6 1.2 9.0 3.6 1.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain AAA PF00004.29 OAG00375.1 - 8.9e-54 181.5 0.0 3.3e-43 147.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OAG00375.1 - 1.5e-28 99.0 1.3 3.3e-28 97.9 1.3 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 OAG00375.1 - 2.3e-15 56.1 0.0 3.9e-10 39.4 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OAG00375.1 - 1.1e-08 35.7 5.2 0.0093 16.4 0.1 4.5 2 2 2 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 OAG00375.1 - 2.1e-07 31.2 0.0 0.017 15.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 OAG00375.1 - 4.9e-06 26.2 0.0 0.00028 20.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 OAG00375.1 - 5e-06 26.5 0.1 0.011 15.8 0.1 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 OAG00375.1 - 5.6e-06 26.2 0.0 0.015 15.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG00375.1 - 6.3e-06 26.5 1.9 0.026 14.8 0.0 3.9 3 1 1 4 4 3 2 AAA domain NACHT PF05729.12 OAG00375.1 - 8e-05 22.6 0.4 0.15 11.9 0.0 3.7 3 0 0 3 3 3 1 NACHT domain AAA_5 PF07728.14 OAG00375.1 - 0.00017 21.6 0.1 0.67 9.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAG00375.1 - 0.00018 21.3 0.3 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 OAG00375.1 - 0.00059 20.0 0.1 0.039 14.1 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 OAG00375.1 - 0.00076 20.0 0.2 2.5 8.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 OAG00375.1 - 0.00096 18.9 0.1 0.1 12.3 0.0 3.0 3 1 0 3 3 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 OAG00375.1 - 0.0018 17.6 0.0 0.72 9.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 OAG00375.1 - 0.0048 17.1 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG00375.1 - 0.005 17.2 0.0 5.4 7.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 OAG00375.1 - 0.0074 15.5 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 OAG00375.1 - 0.011 15.8 0.0 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAG00375.1 - 0.017 14.7 2.6 1.5 8.4 0.1 3.6 2 2 2 4 4 4 0 AAA domain AAA_17 PF13207.6 OAG00375.1 - 0.022 15.2 0.2 2.4 8.6 0.1 3.2 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 OAG00375.1 - 0.032 13.6 0.1 0.78 9.1 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAG00375.1 - 0.036 13.4 0.0 7.8 5.8 0.0 2.3 2 0 0 2 2 2 0 KaiC PEX-2N PF09263.10 OAG00375.1 - 0.053 13.9 0.6 18 5.8 0.1 3.4 3 0 0 3 3 3 0 Peroxisome biogenesis factor 1, N-terminal AAA_28 PF13521.6 OAG00375.1 - 0.093 13.0 0.1 23 5.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG00375.1 - 0.098 13.2 0.0 28 5.2 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.11 OAG00375.1 - 0.15 11.9 0.0 9 6.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 OAG00375.1 - 0.23 11.5 1.1 28 4.7 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit MCM PF00493.23 OAG00376.1 - 9.6e-104 345.4 0.0 1.4e-103 344.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG00376.1 - 1e-32 112.7 0.7 1.8e-32 111.9 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 OAG00376.1 - 4.2e-19 69.1 0.3 9.7e-19 67.9 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 OAG00376.1 - 2.2e-18 66.4 0.4 6.2e-18 65.0 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OAG00376.1 - 3.2e-07 29.9 0.0 2.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG00376.1 - 5.5e-06 26.4 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 OAG00376.1 - 0.011 16.3 0.7 0.046 14.4 0.5 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 OAG00376.1 - 0.015 15.2 0.2 0.051 13.4 0.2 1.9 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 OAG00376.1 - 0.051 13.4 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG00376.1 - 0.15 11.8 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain SHR3_chaperone PF08229.11 OAG00377.1 - 1.8e-76 255.3 0.0 2e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 OAG00377.1 - 0.08 12.9 4.1 0.044 13.8 1.6 1.8 1 1 0 2 2 2 0 Family of unknown function (DUF5453) RNase_J_C PF17770.1 OAG00379.1 - 0.035 15.1 0.1 0.27 12.3 0.1 2.1 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DivIC PF04977.15 OAG00379.1 - 0.083 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator ArfGap PF01412.18 OAG00380.1 - 5.8e-37 126.4 0.1 2e-36 124.6 0.1 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 OAG00380.1 - 0.0054 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain bZIP_1 PF00170.21 OAG00381.1 - 0.037 14.1 10.1 0.082 13.0 10.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OAG00381.1 - 0.059 13.4 13.0 0.14 12.3 13.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 OAG00381.1 - 0.3 11.7 10.5 0.056 14.0 6.0 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor CENP-N PF05238.13 OAG00381.1 - 0.41 9.9 5.9 0.42 9.9 5.9 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like CDC45 PF02724.14 OAG00381.1 - 5.5 5.1 9.0 6.1 5.0 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 OAG00384.1 - 1.9e-62 205.7 29.1 3e-09 37.3 0.1 9.3 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG00384.1 - 1.1e-24 86.6 1.0 2e-05 24.8 0.0 6.7 2 2 5 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG00384.1 - 5.9e-05 22.2 0.0 0.9 8.4 0.0 4.2 4 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 OAG00384.1 - 0.0001 22.8 0.0 0.0002 21.8 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 OAG00384.1 - 0.00036 19.3 2.7 0.49 9.0 0.3 4.6 4 1 1 5 5 5 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 OAG00384.1 - 0.00052 19.4 0.1 5.2 6.3 0.0 4.2 3 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF4550 PF15084.6 OAG00384.1 - 0.0098 16.3 0.0 0.073 13.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4550) Proteasome_A_N PF10584.9 OAG00384.1 - 0.095 12.4 0.3 27 4.6 0.0 4.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.7 OAG00384.1 - 0.13 12.2 0.2 9.2 6.1 0.0 3.2 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term MutS_V PF00488.21 OAG00385.1 - 2.2e-61 207.2 0.2 4.1e-61 206.3 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG00385.1 - 8.1e-33 114.3 0.8 8.1e-33 114.3 0.8 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 OAG00385.1 - 2.9e-07 30.9 0.1 8.7e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAG00385.1 - 4.7e-07 30.0 0.6 4.7e-07 30.0 0.6 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 OAG00385.1 - 0.028 14.0 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG00385.1 - 0.032 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG00385.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain EXS PF03124.14 OAG00386.1 - 1.2e-106 356.8 3.6 1.4e-106 356.6 3.6 1.0 1 0 0 1 1 1 1 EXS family TrkH PF02386.16 OAG00389.1 - 5.6e-77 259.3 13.4 1.4e-72 244.8 6.3 3.1 2 1 0 2 2 2 2 Cation transport protein DUF2207 PF09972.9 OAG00389.1 - 0.31 9.7 1.4 1.3 7.7 0.0 2.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) UL11 PF11094.8 OAG00395.1 - 0.67 9.9 3.4 1.7 8.5 3.4 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein NTP_transf_6 PF06042.11 OAG00396.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase Pex2_Pex12 PF04757.14 OAG00398.1 - 9.4e-43 146.4 4.2 1.5e-42 145.7 4.2 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_UBOX PF13445.6 OAG00398.1 - 3.2e-08 33.5 4.9 6.7e-08 32.4 4.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG00398.1 - 9.2e-08 31.8 6.3 9.2e-08 31.8 6.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG00398.1 - 1.1e-07 31.6 4.9 2.4e-07 30.5 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG00398.1 - 5e-07 29.9 7.1 1.2e-06 28.7 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAG00398.1 - 3.7e-06 26.7 4.5 7e-06 25.8 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG00398.1 - 8.8e-06 25.8 3.9 8.8e-06 25.8 3.9 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAG00398.1 - 0.00022 21.1 4.7 0.00057 19.8 4.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAG00398.1 - 0.00083 19.6 8.1 0.014 15.7 5.8 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAG00398.1 - 0.0011 18.7 4.8 0.0022 17.8 4.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OAG00398.1 - 0.028 14.3 1.7 0.067 13.1 1.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OAG00398.1 - 0.25 11.5 5.0 0.26 11.4 3.3 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 IBR PF01485.21 OAG00398.1 - 0.45 10.8 3.6 0.98 9.7 3.6 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Gelsolin PF00626.22 OAG00399.1 - 9.6e-33 111.9 0.1 2.3e-11 43.4 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Fungal_trans PF04082.18 OAG00400.1 - 1.3e-16 60.5 1.0 1.4e-16 60.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 OAG00401.1 - 2.3e-54 184.9 0.0 3.4e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Phage_holin_4_2 PF04020.13 OAG00401.1 - 0.23 12.1 5.8 0.43 11.3 5.8 1.3 1 0 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV DUF1634 PF07843.11 OAG00401.1 - 0.47 10.6 2.8 1.2 9.3 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) NAD_binding_2 PF03446.15 OAG00403.1 - 7.8e-26 91.1 0.1 2.1e-25 89.7 0.0 1.7 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG00403.1 - 2.3e-09 37.5 0.2 4e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG00403.1 - 3.2e-06 27.6 0.0 7.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAG00403.1 - 2e-05 24.7 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 OAG00403.1 - 0.015 15.3 0.1 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.6 OAG00403.1 - 0.037 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 OAG00403.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AARP2CN PF08142.12 OAG00404.1 - 0.096 12.8 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 AARP2CN (NUC121) domain Erv26 PF04148.13 OAG00405.1 - 5.3e-90 300.7 0.0 6.1e-90 300.6 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 WBS_methylT PF12589.8 OAG00406.1 - 1.6e-13 51.2 2.8 3e-13 50.3 2.8 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 OAG00406.1 - 8.2e-09 36.0 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG00406.1 - 5.8e-08 33.3 0.0 1.1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG00406.1 - 0.00081 19.2 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG00406.1 - 0.0019 18.9 0.0 0.0048 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG00406.1 - 0.036 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OAG00406.1 - 0.054 13.3 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OAG00406.1 - 0.17 11.2 0.0 1.2 8.3 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Iso_dh PF00180.20 OAG00407.1 - 6.4e-85 285.4 0.0 7.7e-85 285.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NAD_binding_2 PF03446.15 OAG00408.1 - 9.4e-30 103.9 0.0 1.5e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG00408.1 - 3.9e-24 85.2 0.0 7.6e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG00408.1 - 2.8e-05 24.6 0.0 0.00038 21.0 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG00408.1 - 0.0032 16.8 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG00408.1 - 0.0042 16.7 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Semialdhyde_dh PF01118.24 OAG00408.1 - 0.075 13.5 0.0 0.33 11.4 0.0 2.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CbiA PF01656.23 OAG00408.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4615 PF15393.6 OAG00409.1 - 0.014 15.9 4.1 0.014 15.9 4.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4615) APG6_N PF17675.1 OAG00409.1 - 0.015 15.9 5.1 0.015 15.9 5.1 3.2 3 1 0 3 3 3 0 Apg6 coiled-coil region tRNA_int_end_N2 PF12928.7 OAG00409.1 - 0.033 14.4 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term G10 PF01125.17 OAG00409.1 - 6.7 6.5 8.1 18 5.1 0.3 2.5 2 0 0 2 2 2 0 G10 protein Ribosomal_L38e PF01781.18 OAG00411.1 - 1.5e-32 111.5 1.7 1.7e-32 111.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Lactamase_B_2 PF12706.7 OAG00412.1 - 2.9e-18 66.1 0.0 4.2e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG00412.1 - 1.1e-14 54.7 0.1 2.8e-14 53.3 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG00412.1 - 0.0039 17.2 3.0 0.0087 16.1 1.9 2.0 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Glyco_hydro_47 PF01532.20 OAG00413.1 - 1.9e-167 557.8 0.0 2.4e-167 557.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Epimerase PF01370.21 OAG00415.1 - 1.4e-15 57.4 0.1 2.6e-15 56.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG00415.1 - 1.9e-09 37.7 0.2 3.7e-09 36.7 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAG00415.1 - 5.7e-09 35.9 0.4 9.1e-09 35.2 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OAG00415.1 - 1.5e-06 27.5 0.1 2.1e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG00415.1 - 4.8e-06 25.8 0.0 9.3e-06 24.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG00415.1 - 5.1e-06 26.1 0.1 0.00025 20.5 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAG00415.1 - 0.0052 16.3 0.1 0.0088 15.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG00415.1 - 0.0087 16.3 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAG00415.1 - 0.013 15.8 0.1 0.023 15.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 OAG00415.1 - 0.013 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 KR domain AlaDh_PNT_C PF01262.21 OAG00415.1 - 0.048 13.0 0.3 0.087 12.1 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_4 PF07993.12 OAG00415.1 - 0.053 12.7 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein ADH_zinc_N PF00107.26 OAG00415.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-RING_2 PF13639.6 OAG00416.1 - 0.0042 17.4 0.3 0.46 10.8 0.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAG00416.1 - 0.015 15.6 0.2 0.14 12.5 0.2 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG00416.1 - 0.036 14.1 0.8 0.16 12.0 0.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Herpes_glycoH_C PF17488.2 OAG00416.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain Prok-RING_4 PF14447.6 OAG00416.1 - 0.13 12.1 0.7 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OAG00417.1 - 4.8e-06 26.8 18.0 3.8e-05 23.9 11.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 OAG00417.1 - 7.8e-06 26.0 12.5 7.8e-06 26.0 12.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAG00417.1 - 1.1e-05 25.2 17.8 2.5e-05 24.0 11.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG00417.1 - 3.4e-05 23.6 10.9 3.4e-05 23.6 10.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG00417.1 - 5.8e-05 22.9 12.4 5.8e-05 22.9 12.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG00417.1 - 0.00051 20.0 9.3 0.00051 20.0 9.3 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG00417.1 - 0.00092 19.1 12.2 0.00092 19.1 12.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG00417.1 - 0.45 10.4 14.1 0.41 10.5 9.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OAG00417.1 - 1 9.5 9.0 2.1 8.5 9.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 OAG00417.1 - 1.1 9.4 6.8 0.2 11.7 2.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG00417.1 - 2.1 8.7 12.5 0.54 10.6 7.9 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Pepsin-I3 PF06394.13 OAG00418.1 - 0.078 13.2 0.8 6.9 6.9 1.5 2.5 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain 2OG-Fe_Oxy_2 PF10014.9 OAG00418.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase CHCH PF06747.13 OAG00420.1 - 9.2e-05 22.5 3.5 0.0002 21.4 3.3 1.7 1 1 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 OAG00420.1 - 0.00066 19.9 1.9 0.00094 19.4 1.9 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 OAG00420.1 - 0.16 12.3 2.6 0.25 11.7 2.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Sod_Fe_C PF02777.18 OAG00421.1 - 2.7e-16 59.6 0.1 2.4e-14 53.3 0.1 2.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain 5_nucleotid PF05761.14 OAG00421.1 - 0.042 12.7 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 5' nucleotidase family MGC-24 PF05283.11 OAG00422.1 - 0.012 16.1 0.1 0.012 16.1 0.1 2.8 2 1 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FixS PF03597.15 OAG00422.1 - 0.2 11.4 0.2 0.51 10.1 0.2 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Myc_target_1 PF15179.6 OAG00422.1 - 0.51 10.2 14.8 0.68 9.8 0.0 3.0 3 1 1 4 4 4 0 Myc target protein 1 Granulin PF00396.18 OAG00422.1 - 8.8 6.8 26.5 5 7.5 6.8 3.4 3 0 0 3 3 3 0 Granulin NAD_Gly3P_dh_C PF07479.14 OAG00423.1 - 3e-46 157.2 0.0 6e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 OAG00423.1 - 5.6e-45 153.1 0.0 1.4e-44 151.9 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Toxin_6 PF05453.12 OAG00424.1 - 0.081 13.4 3.3 0.22 12.0 3.3 1.8 1 0 0 1 1 1 0 BmTXKS1/BmP02 toxin family GREB1 PF15782.5 OAG00424.1 - 1.8 5.6 4.1 2.1 5.4 4.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RAP1 PF07218.11 OAG00424.1 - 3.1 6.0 7.0 3.7 5.7 7.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Menin PF05053.13 OAG00424.1 - 3.4 5.9 4.7 3.9 5.7 4.7 1.1 1 0 0 1 1 1 0 Menin NAD_binding_4 PF07993.12 OAG00425.1 - 3e-41 141.3 0.0 4.5e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG00425.1 - 4.4e-21 75.0 0.0 8.1e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAG00425.1 - 6.9e-07 29.5 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAG00425.1 - 4.5e-06 26.3 0.0 2.4e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SNF2_N PF00176.23 OAG00426.1 - 9.8e-61 205.4 0.6 1.5e-60 204.8 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 OAG00426.1 - 6.5e-09 35.5 8.9 2e-08 34.0 8.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG00426.1 - 3e-08 33.4 8.1 3e-08 33.4 8.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG00426.1 - 3.8e-07 29.9 6.4 3.8e-07 29.9 6.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 OAG00426.1 - 2.5e-05 24.6 0.1 0.00018 21.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 OAG00426.1 - 4.9e-05 23.6 10.1 4.9e-05 23.6 10.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OAG00426.1 - 8e-05 22.5 8.5 8e-05 22.5 8.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG00426.1 - 0.00029 20.6 5.0 0.00078 19.3 5.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAG00426.1 - 0.0021 18.0 8.4 0.0021 18.0 8.4 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG00426.1 - 0.0027 17.9 8.8 0.0091 16.3 8.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OAG00426.1 - 0.0038 17.4 8.2 0.0038 17.4 8.2 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 OAG00426.1 - 0.077 13.1 0.7 0.2 11.8 0.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 OAG00426.1 - 0.25 11.1 8.3 0.7 9.7 8.3 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AMP-binding PF00501.28 OAG00427.1 - 3.6e-72 243.3 0.0 4.7e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG00427.1 - 2.1e-11 44.6 0.6 4.4e-11 43.6 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Peptidase_M24 PF00557.24 OAG00428.1 - 7.1e-46 156.5 0.0 8.8e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 OAG00428.1 - 4.3e-20 71.7 6.9 4.3e-20 71.7 6.9 1.6 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OAG00428.1 - 3e-05 24.0 5.2 7.4e-05 22.8 5.2 1.7 1 0 0 1 1 1 1 MYND finger DUF2116 PF09889.9 OAG00428.1 - 0.29 11.1 1.6 0.73 9.9 1.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) FmiP_Thoc5 PF09766.9 OAG00429.1 - 2.4e-21 76.4 8.1 2.4e-21 76.4 8.1 1.9 1 1 1 2 2 2 1 Fms-interacting protein/Thoc5 DUF349 PF03993.12 OAG00429.1 - 0.0058 16.9 2.1 0.0058 16.9 2.1 2.8 2 1 0 2 2 2 1 Domain of Unknown Function (DUF349) DASH_Dad3 PF08656.10 OAG00429.1 - 0.019 15.0 0.5 0.019 15.0 0.5 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 APG6_N PF17675.1 OAG00429.1 - 0.074 13.6 20.1 0.37 11.3 9.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Cu-oxidase_4 PF02578.15 OAG00429.1 - 0.23 11.0 1.0 1.1 8.8 0.1 2.0 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase AAA_11 PF13086.6 OAG00429.1 - 1.7 8.3 15.1 27 4.5 15.1 2.0 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 OAG00430.1 - 3.3e-43 148.0 46.5 3.3e-43 148.0 46.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily F-box PF00646.33 OAG00431.1 - 2.4e-11 43.2 0.7 4.8e-06 26.3 0.2 2.9 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 OAG00431.1 - 3.2e-11 42.9 0.7 4.5e-07 29.7 0.1 2.8 2 0 0 2 2 2 2 F-box-like RSN1_7TM PF02714.15 OAG00432.1 - 2.8e-73 246.6 14.4 2.8e-73 246.6 14.4 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG00432.1 - 1.8e-39 135.0 1.9 1.8e-39 135.0 1.9 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG00432.1 - 6.6e-39 133.9 0.0 1e-38 133.4 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 OAG00432.1 - 0.00015 20.8 2.3 0.00073 18.5 0.5 2.3 2 0 0 2 2 2 1 Calcium-activated chloride channel FtsL PF04999.13 OAG00432.1 - 0.19 11.8 0.7 40 4.3 0.0 3.0 3 0 0 3 3 3 0 Cell division protein FtsL YMF19 PF02326.15 OAG00432.1 - 1.5 9.6 9.2 0.31 11.8 0.6 3.5 4 0 0 4 4 4 0 Plant ATP synthase F0 Arrestin_N PF00339.29 OAG00433.1 - 8.2e-15 55.1 0.0 6e-14 52.3 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OAG00433.1 - 6.8e-12 46.0 0.3 6.1e-07 30.0 0.0 3.6 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain FCH PF00611.23 OAG00434.1 - 0.0052 17.0 1.2 0.0052 17.0 1.2 2.0 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain FUSC-like PF12805.7 OAG00434.1 - 0.044 12.9 5.2 0.066 12.3 5.2 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Vps51 PF08700.11 OAG00434.1 - 0.28 11.3 3.7 0.63 10.2 0.1 2.7 3 0 0 3 3 3 0 Vps51/Vps67 zf-XS PF03470.14 OAG00434.1 - 0.3 11.4 2.5 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 XS zinc finger domain PCI PF01399.27 OAG00435.1 - 5.1e-13 49.4 0.4 7.7e-12 45.6 0.0 2.9 3 1 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 OAG00435.1 - 1.8e-12 46.7 2.4 5.1e-12 45.3 2.4 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Sigma70_ECF PF07638.11 OAG00435.1 - 0.013 15.4 0.3 0.035 14.0 0.3 1.7 1 0 0 1 1 1 0 ECF sigma factor Phage_TAC_12 PF12363.8 OAG00435.1 - 0.1 13.0 1.1 0.4 11.1 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC YrzO PF14142.6 OAG00435.1 - 2 8.4 4.2 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 YrzO-like protein ADK PF00406.22 OAG00436.1 - 4e-47 160.1 0.0 5.4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAG00436.1 - 2.2e-38 131.8 0.0 3.3e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG00436.1 - 3.3e-10 40.6 0.0 5.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OAG00436.1 - 5.2e-06 26.3 0.5 0.0029 17.3 0.5 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 OAG00436.1 - 0.0018 18.5 0.1 0.01 16.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAG00436.1 - 0.038 13.3 0.2 0.1 11.8 0.2 1.9 1 1 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 OAG00436.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 OAG00436.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 OAG00436.1 - 0.86 9.3 3.0 13 5.5 0.4 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF378 PF04070.12 OAG00438.1 - 0.17 11.8 3.0 0.19 11.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF378) Proteasome PF00227.26 OAG00440.1 - 5.3e-31 107.6 0.0 2.6e-30 105.3 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit HEPN_SAV2148 PF18725.1 OAG00440.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 SAV2148-like HEPN HCNGP PF07818.13 OAG00441.1 - 9.3e-26 90.3 0.1 1.4e-25 89.8 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 OAG00442.1 - 3e-30 105.1 0.0 3.5e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Toprim_C_rpt PF13368.6 OAG00442.1 - 0.047 13.7 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat MARVEL PF01284.23 OAG00443.1 - 9.6e-10 38.7 10.6 1.5e-09 38.1 10.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7tm_7 PF08395.12 OAG00443.1 - 0.024 13.8 1.7 0.034 13.4 1.6 1.3 1 1 0 1 1 1 0 7tm Chemosensory receptor NDUF_B6 PF09782.9 OAG00443.1 - 0.17 12.0 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit SUR7 PF06687.12 OAG00443.1 - 2.9 7.5 10.8 2.5 7.7 5.0 2.3 1 1 1 2 2 2 0 SUR7/PalI family DSBA PF01323.20 OAG00444.1 - 5.9e-24 84.9 0.0 6.6e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain UCH PF00443.29 OAG00445.1 - 7.9e-26 91.1 0.0 1.1e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAG00445.1 - 1.6e-10 41.1 0.1 2.9e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OAG00445.1 - 0.16 11.5 0.2 0.85 9.1 0.2 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cpn60_TCP1 PF00118.24 OAG00446.1 - 1.5e-142 475.7 12.8 1.7e-142 475.5 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 OAG00446.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Ribonuc_2-5A PF06479.12 OAG00447.1 - 2.3e-43 147.4 0.0 4e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 OAG00447.1 - 1.7e-42 145.6 0.0 6.6e-42 143.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00447.1 - 4.7e-20 72.0 0.0 9e-20 71.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG00447.1 - 0.00037 19.4 0.0 0.00068 18.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG00447.1 - 0.0018 18.2 0.5 0.063 13.2 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG00447.1 - 0.0049 16.2 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.21 OAG00447.1 - 0.0058 16.5 0.0 1 9.4 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat Acetyltransf_9 PF13527.7 OAG00448.1 - 4e-05 23.7 0.1 0.00052 20.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG00448.1 - 0.00016 21.8 0.1 0.00028 21.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG00448.1 - 0.00022 21.1 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG00448.1 - 0.016 15.7 0.1 0.025 15.0 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG00448.1 - 0.024 14.8 0.1 0.056 13.6 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG00448.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Methyltransf_3 PF01596.17 OAG00449.1 - 1.6e-11 43.8 0.0 2.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAG00449.1 - 3e-10 41.1 0.0 8.6e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ATP-grasp_3 PF02655.14 OAG00449.1 - 0.034 14.2 0.0 0.087 12.9 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain DHQ_synthase PF01761.20 OAG00450.1 - 1.1e-51 175.5 0.0 1.6e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OAG00450.1 - 4.1e-11 43.0 0.0 6.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 OAG00450.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.5 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase EamA PF00892.20 OAG00451.1 - 1.7e-11 44.4 30.8 2.1e-07 31.2 2.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 OAG00451.1 - 0.00084 18.4 9.5 0.0056 15.7 2.9 2.1 2 0 0 2 2 2 2 Ceramide synthase regulator Nuc_sug_transp PF04142.15 OAG00451.1 - 0.0025 17.0 13.5 0.006 15.8 13.5 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter Proteasome PF00227.26 OAG00452.1 - 6.2e-39 133.4 0.0 7.2e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Enolase_C PF00113.22 OAG00453.1 - 7.5e-155 514.5 0.5 1.1e-154 514.0 0.0 1.4 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OAG00453.1 - 4e-58 195.2 1.1 6.8e-58 194.5 0.4 1.7 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OAG00453.1 - 2e-05 24.3 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAG00453.1 - 0.066 12.4 0.1 0.5 9.5 0.1 2.1 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus EF-hand_7 PF13499.6 OAG00453.1 - 0.25 11.8 0.9 1.1 9.7 0.2 2.3 2 0 0 2 2 2 0 EF-hand domain pair MPC PF03650.13 OAG00455.1 - 1.2e-34 118.8 0.0 1.5e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LSM PF01423.22 OAG00456.1 - 3.9e-06 26.5 0.0 5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 OAG00457.1 - 9.3e-23 80.2 0.0 1.4e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAG00457.1 - 3.9e-20 71.9 0.0 7.9e-20 70.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L5 DUF2700 PF10912.8 OAG00458.1 - 0.00017 21.6 2.3 0.15 12.1 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2700) DUF588 PF04535.12 OAG00458.1 - 0.004 16.9 4.0 0.007 16.2 4.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF588) MARVEL PF01284.23 OAG00458.1 - 0.027 14.5 15.4 0.016 15.2 11.3 2.2 1 1 1 2 2 2 0 Membrane-associating domain SUa-2TM PF18179.1 OAG00458.1 - 0.027 13.8 0.8 0.057 12.7 0.0 1.7 2 0 0 2 2 2 0 SMODS- and Ubiquitin system-associated 2TM effector domain TMEM192 PF14802.6 OAG00458.1 - 0.029 13.5 4.0 0.99 8.5 0.1 2.5 3 0 0 3 3 3 0 TMEM192 family Vma12 PF11712.8 OAG00458.1 - 0.053 13.6 1.1 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cation_efflux PF01545.21 OAG00458.1 - 0.061 13.0 2.1 0.13 12.0 2.1 1.6 1 1 0 1 1 1 0 Cation efflux family DUF3290 PF11694.8 OAG00458.1 - 1 9.3 2.8 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Vpu PF00558.19 OAG00458.1 - 2.2 8.1 5.2 22 4.9 1.8 2.7 2 0 0 2 2 2 0 Vpu protein DUF2157 PF09925.9 OAG00458.1 - 2.4 7.9 5.7 1.7 8.5 3.7 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Yip1 PF04893.17 OAG00458.1 - 8.4 6.1 10.7 0.14 11.9 3.4 1.7 2 1 0 2 2 2 0 Yip1 domain SieB PF14163.6 OAG00459.1 - 0.59 9.6 2.7 1.2 8.6 0.1 2.5 3 0 0 3 3 3 0 Super-infection exclusion protein B Helicase_C PF00271.31 OAG00460.1 - 9.1e-15 55.0 0.0 4.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 OAG00460.1 - 2.9e-14 53.3 0.0 1.4e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG00460.1 - 7.1e-08 32.7 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OAG00460.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OAG00460.1 - 0.015 15.6 0.0 0.094 13.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAG00460.1 - 0.088 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 OAG00460.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Calc_CGRP_IAPP PF00214.19 OAG00460.1 - 0.16 12.3 0.1 0.47 10.8 0.1 1.8 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family WD40 PF00400.32 OAG00462.1 - 2.8e-55 183.0 16.2 3.7e-06 27.6 0.0 12.8 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp13 PF08625.11 OAG00462.1 - 4e-50 169.4 0.0 6.2e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OAG00462.1 - 2.3e-16 59.9 5.7 0.079 13.3 0.0 9.1 4 4 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG00462.1 - 7.6e-05 21.8 0.4 0.38 9.7 0.0 4.8 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG00462.1 - 0.0005 18.8 4.2 0.22 10.1 0.2 4.4 4 2 0 4 4 4 2 Nucleoporin Nup120/160 Pyocin_S PF06958.12 OAG00462.1 - 0.014 15.9 0.1 5.3 7.6 0.0 2.8 2 0 0 2 2 2 0 S-type Pyocin WD40_like PF17005.5 OAG00462.1 - 0.11 11.7 0.0 69 2.6 0.0 4.3 4 1 0 4 4 4 0 WD40-like domain DUF1921 PF09081.10 OAG00462.1 - 2.8 8.3 4.6 5.5 7.3 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1921) Kinesin PF00225.23 OAG00464.1 - 1.2e-92 310.5 0.0 2.3e-92 309.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG00464.1 - 8.5e-22 77.7 0.0 2.1e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Anti-adapt_IraP PF10796.9 OAG00464.1 - 0.02 15.5 0.2 0.059 13.9 0.2 1.8 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein DUF2407_C PF13373.6 OAG00464.1 - 0.075 13.2 7.1 0.036 14.2 3.6 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain Com_YlbF PF06133.11 OAG00464.1 - 0.29 11.7 13.2 0.022 15.4 5.5 2.7 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DUF1840 PF08895.11 OAG00464.1 - 2 8.8 8.4 0.65 10.3 3.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) SLS PF14611.6 OAG00466.1 - 0.05 13.4 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator PAS_11 PF14598.6 OAG00466.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 PAS domain CAP PF00188.26 OAG00467.1 - 7.9e-21 75.2 2.4 1.9e-20 74.0 2.4 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_hydro_12 PF01670.16 OAG00468.1 - 6.6e-60 202.7 11.4 7.7e-60 202.5 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 EHN PF06441.12 OAG00469.1 - 2.4e-26 92.2 0.1 4.4e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.7 OAG00469.1 - 4.9e-12 46.9 2.2 4.9e-12 46.9 2.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG00469.1 - 8.1e-11 42.0 0.0 1.5e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Na_Ca_ex PF01699.24 OAG00471.1 - 2.9e-46 157.2 42.8 3.7e-28 98.4 19.8 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein IncE PF17627.2 OAG00471.1 - 2.6 8.0 6.2 2.9 7.9 0.7 2.3 2 0 0 2 2 2 0 Inclusion membrane protein E Cnd2 PF05786.14 OAG00472.1 - 1.2e-252 841.0 4.9 1.4e-252 840.8 4.9 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF4611 PF15387.6 OAG00472.1 - 0.015 15.5 1.0 0.015 15.5 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CNDH2_N PF06278.11 OAG00472.1 - 0.093 13.0 0.4 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DLH PF01738.18 OAG00473.1 - 3.2e-17 62.8 0.0 4.1e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Nnf1 PF03980.14 OAG00475.1 - 0.13 12.6 1.0 0.3 11.5 0.1 2.1 2 0 0 2 2 2 0 Nnf1 Fcf1 PF04900.12 OAG00476.1 - 3.7e-34 117.1 0.1 7.2e-34 116.2 0.0 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 OAG00476.1 - 1.5e-14 54.3 0.2 2.7e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 PIN like domain Sporozoite_P67 PF05642.11 OAG00477.1 - 1.3 7.0 11.3 1.8 6.6 11.3 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DLIC PF05783.11 OAG00477.1 - 2.2 7.0 4.9 3.4 6.4 4.9 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MOSC PF03473.17 OAG00478.1 - 8.1e-36 122.9 0.0 1.4e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG00478.1 - 2.6e-22 79.0 0.0 5.4e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 OAG00478.1 - 4e-22 78.7 0.0 1.2e-21 77.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Thioredoxin_7 PF13899.6 OAG00481.1 - 1.7e-16 60.1 0.1 1.4e-15 57.2 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 OAG00481.1 - 1.4e-14 53.6 0.1 3.8e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 OAG00481.1 - 2.8e-07 30.7 0.0 8.3e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.6 OAG00481.1 - 0.00038 20.9 0.0 0.00072 20.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Ecm29 PF13001.7 OAG00482.1 - 3.2e-161 537.4 1.2 3e-159 530.9 0.0 3.3 3 1 0 3 3 3 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 OAG00482.1 - 8.4e-09 35.9 0.0 0.0013 19.3 0.1 5.8 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAG00482.1 - 4.2e-07 29.7 2.3 1.2 9.6 0.0 7.9 8 0 0 8 8 8 2 HEAT repeat IFRD PF05004.13 OAG00482.1 - 0.00019 20.7 10.9 0.18 10.9 1.0 5.4 5 1 1 6 6 6 3 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 OAG00482.1 - 0.019 14.1 4.3 0.055 12.6 0.1 3.4 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 OAG00482.1 - 0.034 14.6 15.3 25 5.5 0.0 7.8 8 0 0 8 8 8 0 HEAT-like repeat Sugar_tr PF00083.24 OAG00483.1 - 1.2e-97 327.6 20.3 1.5e-97 327.3 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00483.1 - 1.6e-15 56.9 41.8 9.2e-12 44.5 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily INSIG PF07281.12 OAG00484.1 - 3.9e-72 242.3 0.9 5.2e-72 241.9 0.9 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AAA PF00004.29 OAG00485.1 - 2e-16 60.6 0.0 3.5e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 OAG00485.1 - 0.00066 19.6 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_22 PF13401.6 OAG00485.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAG00485.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 OAG00485.1 - 0.082 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zn_clus PF00172.18 OAG00486.1 - 0.00099 19.2 11.2 0.0017 18.5 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyIII PF03006.20 OAG00487.1 - 3.5e-58 197.0 20.6 4.3e-58 196.7 20.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4131 PF13567.6 OAG00487.1 - 2.2 7.9 14.3 0.97 9.1 0.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) AMP-binding PF00501.28 OAG00488.1 - 3.2e-28 98.5 0.0 1.6e-26 92.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OAG00488.1 - 0.12 13.4 0.1 0.54 11.3 0.0 2.1 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 OAG00489.1 - 3.8e-32 111.6 26.3 3.8e-32 111.6 26.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 OAG00489.1 - 0.066 12.7 0.0 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF4381 PF14316.6 OAG00489.1 - 0.15 12.3 0.2 3.5 7.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF1129 PF06570.11 OAG00489.1 - 7 6.1 7.9 1.2 8.6 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Cu_bind_like PF02298.17 OAG00490.1 - 0.0014 18.6 0.3 2 8.5 0.1 2.2 2 0 0 2 2 2 2 Plastocyanin-like domain DUF4360 PF14273.6 OAG00491.1 - 6.3e-23 81.6 0.1 7.9e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Glyco_hydro_20 PF00728.22 OAG00493.1 - 7.9e-28 97.9 0.1 2.9e-25 89.4 0.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OAG00493.1 - 2.5e-08 34.8 0.0 5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_62 PF03664.13 OAG00494.1 - 1.1e-150 500.5 12.9 1.3e-150 500.3 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 zf-RING_11 PF17123.5 OAG00495.1 - 0.00044 19.9 2.3 0.00087 19.0 1.9 1.8 1 1 1 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 OAG00495.1 - 0.00075 19.8 4.0 0.00075 19.8 4.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG00495.1 - 0.001 19.1 0.8 0.0022 18.0 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG00495.1 - 0.0015 18.3 0.7 0.0052 16.6 0.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG00495.1 - 0.0064 16.3 3.2 0.016 15.1 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG00495.1 - 0.0074 16.2 4.9 0.019 14.9 4.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAG00495.1 - 0.1 12.9 3.8 0.4 11.0 3.8 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain Trypan_PARP PF05887.11 OAG00495.1 - 4 7.4 28.1 3.7 7.5 11.7 2.3 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Pyr_redox_2 PF07992.14 OAG00496.1 - 3.3e-39 134.9 0.0 4.3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG00496.1 - 1.1e-14 54.7 0.1 2.8e-12 47.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG00496.1 - 1.2e-09 37.8 0.0 2.6e-08 33.4 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG00496.1 - 1.2e-06 28.0 0.0 3.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG00496.1 - 0.00026 20.0 0.1 5.7 5.7 0.0 3.5 4 0 0 4 4 4 3 Tryptophan halogenase NAD_binding_7 PF13241.6 OAG00496.1 - 0.0086 16.5 0.0 2.5 8.6 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OAG00496.1 - 0.0091 16.0 0.1 6.7 6.7 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG00496.1 - 0.014 15.6 0.2 0.88 9.8 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DDR PF08841.10 OAG00496.1 - 0.034 13.1 0.0 0.84 8.6 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain TrkA_N PF02254.18 OAG00496.1 - 0.11 12.7 0.0 2.6 8.4 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Abhydrolase_6 PF12697.7 OAG00496.1 - 0.14 12.8 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CheB_methylest PF01339.17 OAG00496.1 - 0.14 11.9 0.3 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 CheB methylesterase VSP PF03302.13 OAG00497.1 - 0.00017 20.6 0.3 0.00021 20.3 0.3 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein MGC-24 PF05283.11 OAG00497.1 - 0.0076 16.7 1.1 0.012 16.1 1.1 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF347 PF03988.12 OAG00497.1 - 0.0082 16.3 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) Podoplanin PF05808.11 OAG00497.1 - 0.0084 16.2 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Flavi_propep PF01570.17 OAG00498.1 - 0.2 11.7 1.2 0.33 10.9 1.2 1.3 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide MFS_1 PF07690.16 OAG00499.1 - 1.9e-43 148.7 56.1 2.3e-43 148.5 53.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG00499.1 - 1.2e-21 76.8 25.1 1.7e-21 76.3 25.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG00499.1 - 6.7e-09 35.1 15.8 6.7e-09 35.1 15.8 3.8 3 1 1 4 4 4 1 Sugar (and other) transporter OATP PF03137.20 OAG00499.1 - 0.0015 16.9 0.9 0.0015 16.9 0.9 2.5 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Stk19 PF10494.9 OAG00500.1 - 6.2e-80 268.4 0.1 1.2e-78 264.2 0.1 2.0 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 DAGAT PF03982.13 OAG00501.1 - 1.3e-88 296.8 0.0 2e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 OAG00501.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Rer1 family Sugar_tr PF00083.24 OAG00502.1 - 1.7e-100 337.0 36.0 2e-100 336.8 36.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00502.1 - 4e-34 118.1 32.8 4e-34 118.1 32.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_1 PF00667.20 OAG00503.1 - 2.1e-52 177.9 0.0 3.4e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG00503.1 - 1.1e-24 87.3 0.1 2e-24 86.4 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG00503.1 - 5.6e-22 78.5 0.0 1.5e-21 77.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain p450 PF00067.22 OAG00504.1 - 1.3e-60 205.5 0.0 1.7e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.21 OAG00505.1 - 0.13 12.4 4.4 0.33 11.1 4.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor CD34_antigen PF06365.12 OAG00505.1 - 0.17 11.4 1.9 0.33 10.5 1.9 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Fungal_trans_2 PF11951.8 OAG00506.1 - 2.6e-06 26.5 0.5 5.2e-06 25.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 OAG00507.1 - 1.4e-25 90.4 0.1 2.7e-25 89.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG00507.1 - 5e-07 29.7 0.1 9.9e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PcrB PF01884.17 OAG00507.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 PcrB family NAD_binding_2 PF03446.15 OAG00507.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF885 PF05960.11 OAG00508.1 - 3.7e-40 139.1 2.8 2.3e-39 136.4 2.8 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Cu-oxidase_2 PF07731.14 OAG00509.1 - 1.9e-23 82.7 1.6 3.5e-20 72.1 1.8 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG00509.1 - 1.8e-18 66.7 0.2 9.9e-18 64.3 0.0 2.3 1 1 1 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG00509.1 - 2.1e-06 28.0 0.0 8.8e-06 25.9 0.0 2.0 2 1 0 2 2 2 1 Multicopper oxidase R3H PF01424.22 OAG00510.1 - 3.5e-16 58.9 0.0 6.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 OAG00510.1 - 4.7e-06 26.5 64.5 0.00033 20.6 18.0 13.7 15 0 0 15 15 15 6 NF-X1 type zinc finger Ribosomal_L37ae PF01780.19 OAG00510.1 - 0.011 15.8 2.2 0.011 15.8 2.2 3.6 3 0 0 3 3 3 0 Ribosomal L37ae protein family ATP-synt_S1 PF05827.12 OAG00511.1 - 0.042 13.7 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) KH_9 PF17904.1 OAG00511.1 - 0.066 13.6 0.1 0.41 11.0 0.0 2.1 2 0 0 2 2 2 0 FMRP KH0 domain EII-Sor PF03609.14 OAG00511.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 PTS system sorbose-specific iic component TMEM18 PF14770.6 OAG00511.1 - 0.14 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 18 N-SET PF11764.8 OAG00513.1 - 5.5e-50 169.8 0.4 5.5e-50 169.8 0.4 3.5 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 OAG00513.1 - 1.5e-25 88.6 0.8 3.9e-25 87.3 0.8 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 OAG00513.1 - 1e-20 74.8 4.7 4.3e-20 72.8 0.1 3.5 3 0 0 3 3 3 1 SET domain RRM_1 PF00076.22 OAG00513.1 - 6.4e-05 22.7 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMRL_synthase PF00885.19 OAG00514.1 - 4.2e-55 185.4 0.0 5.6e-55 185.0 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SIS PF01380.22 OAG00515.1 - 2e-58 195.9 0.1 8.7e-33 113.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OAG00515.1 - 1.2e-16 61.1 0.0 2.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAG00515.1 - 9.9e-10 38.4 0.0 2.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAG00515.1 - 0.0017 17.3 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Prolamin_like PF05617.11 OAG00516.1 - 0.0022 18.1 0.6 0.026 14.7 0.0 2.2 1 1 1 2 2 2 1 Prolamin-like AA_permease PF00324.21 OAG00517.1 - 4.4e-50 170.7 22.2 5.8e-50 170.3 22.2 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OAG00517.1 - 5.1e-25 88.4 1.0 1.2e-10 41.1 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 Aa_trans PF01490.18 OAG00518.1 - 2.2e-84 283.6 33.4 2.6e-84 283.3 33.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 OAG00518.1 - 0.04 14.3 0.5 0.35 11.4 0.5 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) YpmT PF17431.2 OAG00518.1 - 0.046 13.8 0.5 0.046 13.8 0.5 3.1 3 0 0 3 3 3 0 Uncharacterized YmpT-like WD40 PF00400.32 OAG00519.1 - 1.3e-12 48.0 1.5 0.064 14.2 0.2 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 OAG00519.1 - 0.01 14.5 0.0 0.023 13.4 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HSA PF07529.13 OAG00520.1 - 1.3e-15 57.5 0.1 1.3e-15 57.5 0.1 4.8 6 0 0 6 6 6 1 HSA Myb_DNA-bind_6 PF13921.6 OAG00520.1 - 1.3e-13 50.9 0.4 1.3e-13 50.9 0.4 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAG00520.1 - 0.00038 20.6 1.0 0.001 19.2 1.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain NmrA PF05368.13 OAG00521.1 - 6.9e-29 101.1 0.0 8.3e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG00521.1 - 1.3e-14 54.6 0.0 2.1e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG00521.1 - 0.016 15.4 0.2 0.037 14.3 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG00521.1 - 0.026 15.0 0.1 0.045 14.2 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG00521.1 - 0.033 14.3 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 OAG00521.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TctB PF07331.11 OAG00522.1 - 6.4 7.1 22.7 0.078 13.3 10.7 2.8 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family MFS_1 PF07690.16 OAG00523.1 - 5.6e-28 97.9 71.7 5.9e-26 91.2 45.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily THF_DHG_CYH_C PF02882.19 OAG00523.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRIQK PF15168.6 OAG00523.1 - 1 9.3 2.3 1.3 8.9 0.4 2.0 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family F-box PF00646.33 OAG00524.1 - 5.4e-06 26.1 0.2 1.1e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG00524.1 - 0.00013 21.8 0.1 0.00033 20.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like RICTOR_phospho PF14665.6 OAG00526.1 - 0.11 12.8 5.2 6.8 7.1 0.4 2.9 2 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site SEEEED PF14797.6 OAG00526.1 - 2.7 8.1 14.5 7 6.8 14.5 1.7 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex 4HBT_3 PF13622.6 OAG00527.1 - 3.1e-56 191.4 0.0 3.5e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAG00527.1 - 1.7e-06 28.3 0.9 0.00042 20.6 0.2 2.3 2 0 0 2 2 2 2 Thioesterase superfamily C2 PF00168.30 OAG00528.1 - 4.9e-25 87.8 0.0 1.1e-12 48.1 0.0 2.9 2 0 0 2 2 2 2 C2 domain Diphthami_syn_2 PF01902.17 OAG00529.1 - 1.7e-24 86.5 0.0 3.1e-24 85.7 0.0 1.4 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OAG00529.1 - 1.2e-13 51.1 0.0 1.1e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP zf-C2H2 PF00096.26 OAG00530.1 - 9e-13 47.9 13.9 6.1e-07 29.6 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG00530.1 - 2.6e-08 34.0 11.2 0.00037 21.1 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG00530.1 - 8.6e-07 29.1 6.0 0.0019 18.4 1.6 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OAG00530.1 - 2.6e-06 27.6 14.3 2.6e-05 24.4 6.5 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 OAG00530.1 - 1.3e-05 25.4 8.0 0.00041 20.6 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAG00530.1 - 0.0036 17.3 11.0 0.073 13.1 0.9 2.6 2 1 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OAG00530.1 - 0.025 14.2 4.1 1.8 8.2 0.8 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 OAG00530.1 - 0.025 14.5 4.0 0.1 12.6 0.7 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 OAG00530.1 - 0.042 14.5 5.4 0.95 10.1 0.3 2.9 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats LIM PF00412.22 OAG00530.1 - 0.09 13.0 5.3 0.18 12.0 5.3 1.5 1 0 0 1 1 1 0 LIM domain zf_UBZ PF18439.1 OAG00530.1 - 0.095 12.3 2.6 2.2 8.0 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 OAG00530.1 - 0.11 12.3 8.5 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-UBR PF02207.20 OAG00530.1 - 0.23 11.6 2.0 0.46 10.7 2.0 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Macoilin PF09726.9 OAG00530.1 - 0.54 8.7 5.9 0.87 8.1 5.9 1.5 1 0 0 1 1 1 0 Macoilin family Zn-ribbon_8 PF09723.10 OAG00530.1 - 0.67 10.1 4.5 5.1 7.3 0.5 2.7 1 1 1 2 2 2 0 Zinc ribbon domain CDC45 PF02724.14 OAG00530.1 - 0.78 8.0 9.6 1.1 7.5 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_2 PF12756.7 OAG00530.1 - 2.1 8.7 5.9 6.9 7.1 1.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 OAG00530.1 - 3 8.0 8.0 2.1 8.4 3.3 2.5 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.13 OAG00530.1 - 6.1 7.0 6.4 14 5.8 1.3 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like PITH PF06201.13 OAG00532.1 - 1.4e-39 135.8 0.0 3.3e-39 134.5 0.0 1.6 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 OAG00532.1 - 1.3e-17 63.6 0.0 2.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAG00532.1 - 0.00034 20.9 0.0 0.0007 19.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OAG00532.1 - 0.011 15.7 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 OAG00532.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TUG-UBL1 PF11470.8 OAG00533.1 - 1.4e-22 79.7 0.2 6.4e-22 77.6 0.1 2.2 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 OAG00533.1 - 1e-07 32.0 0.0 5.4e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 UBX domain UN_NPL4 PF11543.8 OAG00533.1 - 0.011 16.2 0.2 6.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 OAG00533.1 - 0.019 14.7 0.1 0.15 11.9 0.0 2.6 4 0 0 4 4 4 0 Ubiquitin family Ribosomal_L36e PF01158.18 OAG00534.1 - 1.6e-39 134.0 3.3 1.8e-39 133.8 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Peptidase_M1 PF01433.20 OAG00535.1 - 7.3e-86 287.2 0.3 1.4e-85 286.4 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OAG00535.1 - 6e-84 282.3 1.5 2.4e-83 280.3 1.3 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OAG00535.1 - 3.9e-52 177.1 1.3 1.3e-51 175.4 0.7 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain 2OG-FeII_Oxy PF03171.20 OAG00537.1 - 0.028 14.9 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1838 PF08894.11 OAG00537.1 - 0.15 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) APH PF01636.23 OAG00538.1 - 2.7e-23 83.2 0.5 3.5e-23 82.8 0.5 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family QLQ PF08880.11 OAG00538.1 - 0.0058 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 QLQ DUF1679 PF07914.11 OAG00538.1 - 0.025 13.5 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) LigA PF07746.11 OAG00538.1 - 0.099 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit SARAF PF06682.12 OAG00539.1 - 0.0096 15.6 1.2 0.011 15.4 1.2 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Gastrin PF00918.17 OAG00539.1 - 0.074 14.0 0.4 0.09 13.7 0.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family MRI PF15325.6 OAG00539.1 - 0.13 13.4 2.4 0.15 13.1 2.4 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection Fungal_trans PF04082.18 OAG00540.1 - 2e-05 23.8 0.0 3.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UCR_Fe-S_N PF10399.9 OAG00540.1 - 0.014 14.7 0.3 0.03 13.7 0.3 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal zf-CSL PF05207.13 OAG00543.1 - 3.2e-15 55.6 0.4 5.2e-15 54.9 0.4 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 OAG00543.1 - 4.2e-09 36.4 0.0 7.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.20 OAG00544.1 - 3.2e-107 357.1 2.4 3.8e-107 356.8 2.4 1.1 1 0 0 1 1 1 1 14-3-3 protein Ima1_N PF09779.9 OAG00544.1 - 0.11 13.4 0.0 3 8.7 0.0 2.8 3 0 0 3 3 3 0 Ima1 N-terminal domain ARL2_Bind_BART PF11527.8 OAG00544.1 - 0.11 12.6 0.3 8.4 6.5 0.2 2.4 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART DUF327 PF03885.13 OAG00544.1 - 0.14 12.1 1.2 0.58 10.1 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF327) DUF1640 PF07798.11 OAG00545.1 - 1.9e-55 187.6 13.3 2.5e-55 187.2 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LMBR1 PF04791.16 OAG00545.1 - 0.011 14.7 4.1 0.013 14.4 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_rep_O PF04492.13 OAG00545.1 - 0.11 13.1 0.8 0.25 12.0 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage replication protein O GNAT_acetyltr_2 PF13718.6 OAG00545.1 - 0.13 11.7 3.2 0.18 11.2 0.2 2.0 1 1 1 2 2 2 0 GNAT acetyltransferase 2 His_kinase PF06580.13 OAG00545.1 - 0.29 11.5 3.1 0.19 12.1 0.4 2.1 1 1 1 2 2 2 0 Histidine kinase WW PF00397.26 OAG00546.1 - 1.6e-10 40.8 1.6 4.9e-10 39.3 1.6 1.9 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 OAG00546.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoD-like phosphatase adh_short PF00106.25 OAG00548.1 - 1e-24 87.1 0.3 2.7e-23 82.4 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00548.1 - 8e-18 64.9 0.5 1.6e-16 60.6 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00548.1 - 3.8e-05 23.7 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG00548.1 - 0.00055 19.5 0.7 0.0029 17.1 0.7 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 OAG00549.1 - 1.4e-10 40.7 0.8 1.6e-06 27.4 0.9 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG00549.1 - 1.4e-06 28.3 11.9 2.6e-06 27.5 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 OAG00550.1 - 1.8e-32 112.9 0.3 2.3e-32 112.5 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 OAG00550.1 - 7e-05 22.4 0.3 0.00015 21.3 0.3 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 OAG00550.1 - 0.00033 21.3 4.7 0.00033 21.3 4.7 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.28 OAG00550.1 - 0.00049 19.1 0.0 0.0013 17.7 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG00550.1 - 0.0023 17.4 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 OAG00550.1 - 0.0046 15.7 0.1 0.0067 15.1 0.1 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) TRI12 PF06609.13 OAG00551.1 - 3.9e-48 164.3 21.4 4.6e-48 164.1 21.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG00551.1 - 1.9e-21 76.4 41.0 1.9e-21 76.4 41.0 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG00551.1 - 7.6e-10 38.2 8.5 7.6e-10 38.2 8.5 3.9 3 1 1 4 4 4 1 Sugar (and other) transporter DUF5583 PF17821.1 OAG00552.1 - 0.18 11.8 0.2 5.4 7.0 0.0 2.7 3 1 0 3 3 3 0 Family of unknown function (DUF5583) HpcH_HpaI PF03328.14 OAG00553.1 - 2.4e-36 125.0 0.0 3e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 OAG00553.1 - 0.049 12.5 0.0 0.082 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain PEP_mutase PF13714.6 OAG00553.1 - 0.067 12.6 0.4 4.7 6.6 0.0 2.7 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase FMO-like PF00743.19 OAG00554.1 - 5.2e-16 58.2 0.2 3.5e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG00554.1 - 4.1e-14 52.5 0.0 1.3e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG00554.1 - 1.4e-11 44.1 0.0 1.1e-09 37.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG00554.1 - 4.9e-11 42.7 0.0 1.4e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG00554.1 - 1.4e-10 40.9 0.0 1.4e-07 31.0 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG00554.1 - 1.1e-05 24.7 0.0 2.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG00554.1 - 0.00038 21.0 0.1 0.28 11.8 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG00554.1 - 0.00069 18.8 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG00554.1 - 0.00079 18.2 0.1 0.0036 16.0 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 OAG00554.1 - 0.0011 18.2 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG00554.1 - 0.0014 18.3 0.1 0.02 14.5 0.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG00554.1 - 0.018 15.1 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OAG00554.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAG00554.1 - 0.028 14.4 0.0 0.31 11.0 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG00554.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase WD40 PF00400.32 OAG00555.1 - 6.6e-20 71.1 23.2 1.7e-06 28.7 0.3 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 OAG00555.1 - 1.2e-16 61.0 0.4 2.1e-16 60.2 0.4 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 OAG00555.1 - 4.5e-07 28.9 2.7 0.00011 21.0 0.1 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 DUF3060 PF11259.8 OAG00555.1 - 0.062 13.0 0.1 4.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3060) Trm112p PF03966.16 OAG00556.1 - 3.3e-10 40.4 0.0 6.7e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 OAG00556.1 - 0.052 14.1 0.2 0.089 13.3 0.2 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain ROS_MUCR PF05443.11 OAG00556.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Rad60-SLD PF11976.8 OAG00557.1 - 7.1e-24 83.4 0.1 2.4e-21 75.3 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAG00557.1 - 1.6e-06 27.8 0.1 0.00021 21.0 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin family TmoB PF06234.12 OAG00557.1 - 0.076 13.1 0.1 0.24 11.5 0.1 1.9 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) Miga PF10265.9 OAG00557.1 - 0.79 8.6 9.1 1.3 7.9 9.1 1.3 1 0 0 1 1 1 0 Mitoguardin AAA_13 PF13166.6 OAG00557.1 - 1.9 7.0 13.7 0.18 10.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain LCD1 PF09798.9 OAG00557.1 - 7.2 5.0 6.7 9.5 4.6 6.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein LSM PF01423.22 OAG00558.1 - 6.2e-20 70.7 0.0 7.1e-20 70.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 OAG00558.1 - 0.00054 20.0 0.0 0.00065 19.7 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 OAG00558.1 - 0.0023 18.0 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain adh_short PF00106.25 OAG00559.1 - 9.3e-23 80.7 0.0 1.6e-22 79.9 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00559.1 - 6.5e-18 65.1 0.0 1.3e-17 64.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00559.1 - 1.5e-06 28.3 0.1 2.4e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 OAG00559.1 - 0.048 13.2 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 OAG00559.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fer2_3 PF13085.6 OAG00561.1 - 6.7e-32 109.7 0.0 1.1e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OAG00561.1 - 1.1e-08 35.5 6.8 1.1e-08 35.5 6.8 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAG00561.1 - 2e-07 31.4 8.3 2e-07 31.4 8.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAG00561.1 - 1.1e-06 28.6 3.6 1.1e-06 28.6 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OAG00561.1 - 0.002 18.0 2.1 0.0097 15.8 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 OAG00561.1 - 0.0054 17.3 5.4 0.0054 17.3 5.4 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 OAG00561.1 - 0.51 10.6 0.1 0.51 10.6 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAG00561.1 - 2.4 8.4 12.0 16 5.7 10.2 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Zn_clus PF00172.18 OAG00562.1 - 6.1e-07 29.5 10.8 1e-06 28.8 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAG00563.1 - 4.7e-90 302.6 19.3 6.1e-90 302.2 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00563.1 - 3.6e-20 72.2 33.1 1.3e-16 60.5 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG00563.1 - 2.9e-09 36.0 17.1 3.8e-05 22.4 4.9 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Alpha-amylase PF00128.24 OAG00564.1 - 1.4e-110 370.0 0.0 2e-110 369.5 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OAG00564.1 - 7.9e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OAG00564.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain YqeY PF09424.10 OAG00565.1 - 0.084 12.9 0.8 0.11 12.5 0.8 1.2 1 0 0 1 1 1 0 Yqey-like protein DUF4064 PF13273.6 OAG00566.1 - 0.044 14.1 0.2 0.044 14.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Lipase_3 PF01764.25 OAG00567.1 - 1.2e-32 112.7 0.0 1.9e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG00567.1 - 6.9e-05 23.5 2.7 0.00011 22.9 2.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG00567.1 - 0.00054 19.3 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG00567.1 - 0.0015 18.7 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 OAG00567.1 - 0.0032 17.2 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.8 OAG00567.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Cutinase PF01083.22 OAG00567.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.7 OAG00567.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 OAG00567.1 - 0.033 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 OAG00567.1 - 0.051 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OAG00567.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 OAG00567.1 - 0.083 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_M16_C PF05193.21 OAG00568.1 - 6.8e-23 81.6 0.0 9.9e-21 74.6 0.0 2.8 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG00568.1 - 7e-08 32.6 0.2 2e-05 24.6 0.0 3.1 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) MapZ_EC1 PF18041.1 OAG00568.1 - 3.8 7.8 6.3 13 6.1 0.2 3.2 4 0 0 4 4 4 0 MapZ extracellular domain 1 Zw10 PF06248.13 OAG00570.1 - 1.8e-08 33.4 3.2 3.4e-08 32.5 3.2 1.5 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 OAG00570.1 - 2.9e-07 30.4 0.6 5.9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal DUF948 PF06103.11 OAG00570.1 - 0.17 12.2 4.2 1.5 9.1 0.9 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Amidase_5 PF05382.13 OAG00571.1 - 0.014 15.3 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase RhoGEF PF00621.20 OAG00572.1 - 9.7e-34 117.2 0.8 2.7e-33 115.7 0.1 2.1 2 0 0 2 2 2 1 RhoGEF domain RabGAP-TBC PF00566.18 OAG00574.1 - 1.2e-24 87.2 0.0 2.2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 OAG00574.1 - 2.9e-07 29.1 1.4 2.9e-07 29.1 1.4 2.1 2 0 0 2 2 2 2 SBE2, cell-wall formation DUF4407 PF14362.6 OAG00574.1 - 1.6 8.0 3.8 3.5 6.9 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ferric_reduct PF01794.19 OAG00576.1 - 3.6e-15 56.2 9.1 6.5e-15 55.3 9.1 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG00576.1 - 3e-09 37.2 0.0 8.5e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG00576.1 - 0.0021 18.1 0.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 FAD-binding domain Glyco_hydro_7 PF00840.20 OAG00577.1 - 8.9e-204 677.1 25.0 1e-203 677.0 25.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fungal_trans PF04082.18 OAG00578.1 - 1.5e-15 56.9 1.2 2.4e-15 56.3 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG00578.1 - 1.4e-07 31.5 7.0 2.8e-07 30.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UL21a PF17636.2 OAG00578.1 - 0.17 11.9 0.3 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Viral Unique Long protein 21a SET PF00856.28 OAG00580.1 - 1.6e-13 51.4 0.1 1.3e-12 48.4 0.1 2.2 1 1 0 1 1 1 1 SET domain TPR_7 PF13176.6 OAG00580.1 - 0.024 14.7 0.9 1.2 9.4 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG00580.1 - 0.092 13.1 0.3 33 4.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG00580.1 - 0.74 9.8 3.9 11 6.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG00580.1 - 3.1 8.1 6.5 6 7.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_10 PF00331.20 OAG00581.1 - 4.7e-101 338.1 1.4 5.7e-101 337.8 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 OAG00581.1 - 1.1e-13 50.8 14.5 1.1e-13 50.8 14.5 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Rubella_E2 PF05749.11 OAG00581.1 - 0.58 9.6 12.9 2.1 7.7 6.2 3.0 3 0 0 3 3 3 0 Rubella membrane glycoprotein E2 Zn_clus PF00172.18 OAG00585.1 - 6.8e-07 29.3 13.1 1.8e-06 28.0 13.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG00585.1 - 2.3e-06 26.7 0.1 3.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 OAG00586.1 - 1.8e-13 50.2 0.0 2.2e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DNA_pol_A_exo1 PF01612.20 OAG00588.1 - 1.6e-16 60.5 0.0 2.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease MecA PF05389.12 OAG00588.1 - 0.49 10.0 2.9 1.1 8.8 0.3 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) RR_TM4-6 PF06459.12 OAG00588.1 - 4.4 7.1 8.8 0.54 10.0 1.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LSM PF01423.22 OAG00589.1 - 2e-20 72.3 0.4 2.5e-20 71.9 0.4 1.1 1 0 0 1 1 1 1 LSM domain HMG_box PF00505.19 OAG00591.1 - 3.5e-12 46.5 0.1 3.5e-12 46.5 0.1 2.0 3 0 0 3 3 3 1 HMG (high mobility group) box SAM_1 PF00536.30 OAG00591.1 - 6.4e-12 45.7 0.5 1.2e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 OAG00591.1 - 8.6e-08 32.7 0.3 2e-07 31.5 0.3 1.7 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 OAG00591.1 - 2.3e-07 30.8 0.0 5.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3074 PF11274.8 OAG00592.1 - 1e-40 139.7 0.2 1.4e-40 139.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Ral PF11058.8 OAG00592.1 - 0.12 11.9 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral HTH_32 PF13565.6 OAG00597.1 - 3.8e-05 24.2 1.4 0.00028 21.5 0.1 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 OAG00597.1 - 0.015 15.1 1.4 0.03 14.1 0.6 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 OAG00597.1 - 0.032 14.2 0.3 0.13 12.3 0.3 2.1 1 1 0 1 1 1 0 Winged helix-turn helix AA_permease_2 PF13520.6 OAG00598.1 - 4.5e-54 183.9 52.5 5.8e-54 183.5 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG00598.1 - 7.1e-21 74.3 46.8 9.7e-21 73.9 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease Pox_EPC_I2-L1 PF12575.8 OAG00598.1 - 0.054 13.7 1.4 0.34 11.2 0.1 2.9 1 1 1 2 2 2 0 Poxvirus entry protein complex L1 and I2 Ribosomal_60s PF00428.19 OAG00599.1 - 0.0032 18.0 8.7 0.0037 17.8 8.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MRP PF09387.10 OAG00600.1 - 0.032 14.2 0.7 0.051 13.6 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Glyco_hydro_43 PF04616.14 OAG00604.1 - 8.4e-18 64.7 4.4 1.4e-17 64.0 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 OAG00604.1 - 1.3e-09 38.4 0.6 2.9e-09 37.2 0.6 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) Tfb2_C PF18307.1 OAG00605.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain Acetyltransf_1 PF00583.25 OAG00606.1 - 4e-07 30.3 0.0 8.5e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG00606.1 - 5.2e-07 29.7 0.0 9.2e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG00606.1 - 5.1e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG00606.1 - 0.00067 19.6 0.0 0.0025 17.7 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAG00606.1 - 0.019 15.0 0.0 4.1 7.5 0.0 2.3 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain ThylakoidFormat PF11264.8 OAG00606.1 - 0.093 12.4 0.1 10 5.7 0.0 2.1 2 0 0 2 2 2 0 Thylakoid formation protein Colicin_D PF11429.8 OAG00606.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 1 0 1 1 1 0 Colicin D Acetyltransf_1 PF00583.25 OAG00608.1 - 9.5e-15 54.9 0.0 1.3e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG00608.1 - 4.8e-08 33.0 0.0 6.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG00608.1 - 3.4e-06 26.9 0.0 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG00608.1 - 1.7e-05 25.1 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG00608.1 - 0.0029 17.7 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAG00608.1 - 0.017 15.8 0.0 0.026 15.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG00608.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pyr_redox_2 PF07992.14 OAG00609.1 - 6e-14 51.9 0.4 2e-13 50.2 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG00609.1 - 4.9e-10 39.5 3.9 2.7e-08 33.9 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG00609.1 - 9.3e-09 34.2 0.0 3.8e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.24 OAG00609.1 - 1e-08 35.2 5.7 0.0015 18.2 0.2 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG00609.1 - 9e-08 32.2 0.8 3.4e-07 30.4 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG00609.1 - 2.1e-06 27.2 1.7 5.2e-05 22.6 1.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG00609.1 - 5.3e-06 26.9 1.7 0.033 14.7 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG00609.1 - 2e-05 24.1 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 OAG00609.1 - 6.4e-05 22.2 1.5 0.0016 17.7 0.3 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAG00609.1 - 0.00052 18.8 4.2 0.0019 17.0 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG00609.1 - 0.00052 19.4 4.8 0.012 14.9 0.4 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAG00609.1 - 0.002 17.5 4.7 0.088 12.1 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG00609.1 - 0.0022 17.2 6.2 0.035 13.2 0.1 2.8 3 0 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.14 OAG00609.1 - 0.0022 16.9 5.3 0.02 13.8 0.4 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 OAG00609.1 - 0.0033 16.6 8.3 0.09 11.8 2.1 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAG00609.1 - 0.0094 15.2 0.2 0.0094 15.2 0.2 2.2 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 OAG00609.1 - 0.033 13.4 2.5 0.083 12.1 0.4 2.2 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 OAG00609.1 - 0.092 11.8 0.4 0.53 9.3 0.1 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein LolA_2 PF16584.5 OAG00609.1 - 0.14 12.0 0.4 0.33 10.8 0.4 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA MCRA PF06100.11 OAG00609.1 - 0.2 10.4 0.0 0.41 9.4 0.0 1.5 1 0 0 1 1 1 0 MCRA family Agouti PF05039.12 OAG00610.1 - 0.17 12.6 6.0 0.14 12.9 2.0 2.4 2 0 0 2 2 2 0 Agouti protein CWC25 PF12542.8 OAG00613.1 - 0.007 17.3 3.2 0.007 17.3 3.2 3.2 2 2 0 2 2 2 1 Pre-mRNA splicing factor STI1 PF17830.1 OAG00613.1 - 0.16 11.9 15.3 0.98 9.4 0.5 5.8 6 1 1 7 7 7 0 STI1 domain PDE4_UCR PF18100.1 OAG00613.1 - 0.38 11.4 2.0 0.82 10.3 0.2 2.4 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF445 PF04286.12 OAG00613.1 - 3.6 7.3 17.2 24 4.6 12.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF445) MFS_1 PF07690.16 OAG00614.1 - 7.9e-33 113.8 37.6 7.9e-33 113.8 37.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG00614.1 - 0.00018 20.9 5.4 0.00018 20.9 5.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ABC_tran PF00005.27 OAG00618.1 - 5.2e-46 156.6 0.4 4.2e-24 85.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG00618.1 - 7.9e-24 85.0 3.1 1.6e-05 24.9 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OAG00618.1 - 2.4e-23 82.8 39.9 5.4e-15 55.3 21.0 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 OAG00618.1 - 5.8e-09 35.7 2.3 0.013 15.0 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG00618.1 - 6.8e-09 35.3 1.4 6.2e-05 22.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG00618.1 - 1.4e-06 28.9 2.7 0.0094 16.5 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAG00618.1 - 6.8e-06 26.0 0.0 0.012 15.3 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG00618.1 - 0.00011 22.2 0.5 0.37 10.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 OAG00618.1 - 0.00031 20.4 0.2 0.29 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OAG00618.1 - 0.0077 16.0 0.4 2.4 7.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG00618.1 - 0.0079 16.6 0.3 1.5 9.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG00618.1 - 0.0087 16.3 0.1 2.2 8.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 OAG00618.1 - 0.094 13.1 1.5 1.9 8.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OAG00618.1 - 0.18 12.0 0.5 31 4.9 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 OAG00618.1 - 0.25 10.6 0.4 6.3 6.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 OAG00618.1 - 0.28 11.4 2.1 7.8 6.7 0.7 2.4 2 0 0 2 2 2 0 AAA domain CFEM PF05730.11 OAG00621.1 - 8.4e-10 38.6 9.8 1.4e-09 37.9 9.8 1.3 1 0 0 1 1 1 1 CFEM domain DUF4690 PF15756.5 OAG00621.1 - 0.0076 16.8 0.5 0.016 15.8 0.5 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage TIL PF01826.17 OAG00621.1 - 7.6 6.9 8.0 14 6.0 8.0 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain LRR_8 PF13855.6 OAG00624.1 - 1e-09 38.0 7.6 5.5e-09 35.7 3.0 3.0 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 OAG00624.1 - 1.8e-09 37.7 14.5 1.2e-06 28.7 1.4 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAG00624.1 - 0.0018 17.8 0.7 0.0039 16.7 0.7 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 OAG00624.1 - 0.0095 15.9 7.2 2.5 8.4 0.4 4.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 OAG00624.1 - 0.37 11.5 14.7 11 7.0 0.8 5.6 4 1 0 4 4 4 0 Leucine Rich Repeat Glyco_hydro_7 PF00840.20 OAG00629.1 - 5.8e-208 690.9 18.4 7.4e-208 690.6 18.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 OAG00629.1 - 3.2e-10 39.8 16.0 3.2e-10 39.8 16.0 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Orn_Arg_deC_N PF02784.16 OAG00631.1 - 1.5e-82 276.7 0.0 2.2e-82 276.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OAG00631.1 - 3.9e-20 71.9 0.0 5.3e-20 71.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OAG00631.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF3106 PF11304.8 OAG00632.1 - 0.54 10.7 7.8 0.63 10.5 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) G-patch_2 PF12656.7 OAG00633.1 - 1.7e-22 79.2 0.3 1.7e-22 79.2 0.3 3.9 4 1 0 4 4 4 1 G-patch domain G-patch PF01585.23 OAG00633.1 - 0.069 13.1 0.3 0.2 11.6 0.3 1.9 1 0 0 1 1 1 0 G-patch domain Frag1 PF10277.9 OAG00634.1 - 7.4e-44 149.9 17.7 8.6e-44 149.7 17.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family AMP-binding PF00501.28 OAG00637.1 - 2.3e-100 336.1 0.1 2.7e-100 335.9 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG00637.1 - 2.9e-14 53.8 0.0 6.7e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_transf_20 PF00982.21 OAG00641.1 - 3.8e-162 540.2 0.2 7.5e-162 539.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAG00641.1 - 6.3e-43 146.6 0.5 1.4e-42 145.4 0.1 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase hNIFK_binding PF12196.8 OAG00641.1 - 0.08 12.5 0.3 0.74 9.4 0.0 2.5 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Glyco_transf_5 PF08323.11 OAG00641.1 - 0.1 12.3 0.3 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain SnoaL_4 PF13577.6 OAG00642.1 - 1.9e-23 83.0 0.0 2.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG00642.1 - 2.8e-06 27.9 0.0 4.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG00642.1 - 0.0021 18.4 0.0 0.0028 18.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3225 PF11533.8 OAG00642.1 - 0.0048 16.6 0.0 0.0068 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) Scytalone_dh PF02982.14 OAG00642.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase SnoaL PF07366.12 OAG00642.1 - 0.035 13.9 0.0 0.052 13.4 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Lumazine_bd_2 PF12893.7 OAG00642.1 - 0.13 12.9 0.0 0.47 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative lumazine-binding C2 PF00168.30 OAG00643.1 - 4.7e-12 46.1 0.0 9.2e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF5486 PF17588.2 OAG00643.1 - 0.088 12.7 0.8 4.2 7.3 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5486) NACHT PF05729.12 OAG00645.1 - 7e-11 42.3 0.1 3.8e-10 39.9 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG00645.1 - 2.9e-08 34.3 0.3 2.7e-07 31.1 0.0 2.7 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG00645.1 - 1.3e-05 25.5 0.0 9.2e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 OAG00645.1 - 0.00041 19.7 0.1 0.35 10.0 0.0 2.5 2 0 0 2 2 2 2 KAP family P-loop domain AAA_18 PF13238.6 OAG00645.1 - 0.0032 18.0 0.0 0.013 16.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 OAG00645.1 - 0.011 15.8 0.0 0.86 9.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 OAG00645.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OAG00645.1 - 0.017 15.6 0.1 0.1 13.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 OAG00645.1 - 0.021 14.5 0.1 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG00645.1 - 0.027 14.8 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OAG00645.1 - 0.11 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAG00645.1 - 0.12 12.4 0.0 0.59 10.2 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 OAG00645.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 FAD-oxidase_C PF02913.19 OAG00645.1 - 0.15 11.7 0.0 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain cobW PF02492.19 OAG00645.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF5134 PF17197.4 OAG00646.1 - 0.11 12.4 1.0 0.27 11.1 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) LCCL PF03815.19 OAG00647.1 - 5e-19 68.2 0.0 7.9e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 LCCL domain APOC4 PF15119.6 OAG00647.1 - 0.063 13.5 1.0 0.13 12.5 1.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C4 CcmD PF04995.14 OAG00647.1 - 2.9 8.1 5.9 32 4.7 1.7 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Glyco_hydro_43 PF04616.14 OAG00650.1 - 3.8e-37 128.2 0.1 5.6e-29 101.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG00650.1 - 1.4e-08 34.7 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain p450 PF00067.22 OAG00651.1 - 1.5e-42 146.0 0.0 2.3e-42 145.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 OAG00652.1 - 1.7e-66 224.3 0.0 2.6e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00652.1 - 7.2e-41 140.2 0.0 1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG00652.1 - 2.3e-07 30.4 0.0 5.5e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG00652.1 - 5.1e-05 22.4 0.0 5.1e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAG00652.1 - 0.0032 17.4 1.8 0.43 10.5 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG00652.1 - 0.027 13.8 0.3 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OAG00652.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AA_permease PF00324.21 OAG00653.1 - 3e-147 491.1 36.9 3.7e-147 490.8 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG00653.1 - 1.8e-38 132.5 39.1 2.2e-38 132.2 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4310 PF14187.6 OAG00653.1 - 0.003 17.3 1.7 0.003 17.3 1.7 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4310) Deltameth_res PF16020.5 OAG00653.1 - 0.048 13.5 1.0 9.6 6.2 0.0 3.9 3 0 0 3 3 3 0 Deltamethrin resistance DUF4781 PF16013.5 OAG00653.1 - 0.061 12.1 0.4 0.13 11.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) KH_8 PF17903.1 OAG00654.1 - 1.9e-06 27.8 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OAG00654.1 - 0.028 14.2 1.0 0.05 13.4 1.0 1.4 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 OAG00655.1 - 6e-247 820.5 0.2 8.1e-247 820.0 0.2 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.11 OAG00655.1 - 0.0017 18.0 0.2 0.0038 16.9 0.2 1.5 1 0 0 1 1 1 1 TraH_2 DUF4551 PF15087.6 OAG00655.1 - 2.8 6.7 5.5 4.2 6.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Aldo_ket_red PF00248.21 OAG00656.1 - 1e-60 205.4 0.0 1.3e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fijivirus_P9-2 PF06837.11 OAG00658.1 - 0.011 15.2 0.7 0.027 13.9 0.7 1.6 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF5360 PF17314.2 OAG00658.1 - 0.9 9.6 5.0 0.42 10.7 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5360) GMC_oxred_N PF00732.19 OAG00659.1 - 1.7e-60 204.9 0.0 3.5e-60 203.9 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG00659.1 - 7.1e-26 91.4 0.0 1.3e-25 90.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG00659.1 - 4.3e-08 33.1 0.0 2.5e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG00659.1 - 3.2e-06 26.5 0.4 0.038 13.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG00659.1 - 3.4e-06 26.5 0.1 0.025 13.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG00659.1 - 0.0009 19.4 0.1 0.0023 18.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG00659.1 - 0.0017 17.5 0.1 0.0037 16.4 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG00659.1 - 0.011 15.1 0.7 0.42 9.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG00659.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG00659.1 - 0.048 14.2 0.5 0.37 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG00659.1 - 0.082 13.2 0.1 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 OAG00659.1 - 0.091 11.4 0.4 0.43 9.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAG00659.1 - 0.27 10.4 1.0 0.42 9.8 0.1 1.7 2 0 0 2 2 2 0 Thi4 family HATPase_c PF02518.26 OAG00662.1 - 1.1e-24 87.0 0.0 3e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG00662.1 - 1.7e-22 79.7 0.1 3.5e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG00662.1 - 1.8e-09 37.5 0.0 5.6e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Sec34 PF04136.15 OAG00662.1 - 0.077 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Sec34-like family Antigen_Bd37 PF11641.8 OAG00662.1 - 0.081 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein p450 PF00067.22 OAG00663.1 - 2.5e-26 92.5 0.0 3.6e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PQQ_2 PF13360.6 OAG00664.1 - 6.3e-12 45.6 0.2 7.7e-06 25.7 0.1 3.7 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 OAG00664.1 - 3e-10 39.5 6.1 0.00068 19.4 0.1 5.6 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.6 OAG00664.1 - 2.7e-06 27.7 21.3 1.6 9.4 0.1 7.3 9 0 0 9 9 9 5 PQQ-like domain bZIP_1 PF00170.21 OAG00664.1 - 0.078 13.1 4.7 0.15 12.2 3.5 1.9 2 0 0 2 2 2 0 bZIP transcription factor MerR-DNA-bind PF09278.11 OAG00664.1 - 0.56 10.8 6.1 1.7 9.2 4.5 2.4 2 1 0 2 2 2 0 MerR, DNA binding Fungal_trans_2 PF11951.8 OAG00666.1 - 8e-60 202.7 0.3 1.2e-59 202.1 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG00666.1 - 2.9e-09 36.9 7.0 7.2e-09 35.6 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3624 PF12292.8 OAG00666.1 - 0.095 13.1 1.1 0.35 11.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Pam17 PF08566.10 OAG00667.1 - 2e-61 206.7 0.0 2.6e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 CMAS PF02353.20 OAG00668.1 - 2.6e-61 207.3 0.1 3.3e-61 207.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAG00668.1 - 5e-09 36.2 0.0 8.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG00668.1 - 6e-09 36.4 0.0 1.6e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG00668.1 - 1.1e-08 35.7 0.0 2.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OAG00668.1 - 0.0049 16.4 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 OAG00668.1 - 0.0062 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 OAG00668.1 - 0.023 15.5 0.0 0.049 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAG00668.1 - 0.085 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAG00668.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Y_phosphatase3 PF13350.6 OAG00669.1 - 3.3e-46 158.1 0.0 4.4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OAG00669.1 - 2.2e-11 43.6 0.1 3.5e-10 39.7 0.1 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAG00669.1 - 0.00063 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OAG00669.1 - 0.0014 18.5 0.0 0.0061 16.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 OAG00669.1 - 0.0058 15.6 0.2 0.01 14.8 0.0 1.5 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Eisosome1 PF12757.7 OAG00670.1 - 1.2e-36 125.8 13.6 1.2e-36 125.8 13.6 3.9 3 1 0 3 3 3 1 Eisosome protein 1 Striatin PF08232.12 OAG00670.1 - 0.0071 16.9 5.2 0.0071 16.9 5.2 4.5 2 2 1 3 3 3 1 Striatin family PMM PF03332.13 OAG00674.1 - 2.7e-102 341.2 0.0 3.2e-102 341.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.13 OAG00674.1 - 0.014 14.9 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase KAR9 PF08580.10 OAG00676.1 - 0.95 7.9 14.1 1.2 7.6 14.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 p450 PF00067.22 OAG00677.1 - 5.8e-48 163.8 0.0 7.8e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FTH PF01827.27 OAG00678.1 - 0.00073 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 FTH domain Pkinase PF00069.25 OAG00679.1 - 2.3e-59 200.9 0.0 2.7e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00679.1 - 1.1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG00679.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OAG00679.1 - 0.033 13.0 0.0 0.077 11.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OAG00679.1 - 0.038 13.3 0.1 0.066 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG00679.1 - 0.053 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain DUF3764 PF12594.8 OAG00679.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) RRM_1 PF00076.22 OAG00680.1 - 4.5e-08 32.8 0.0 1.3e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG00680.1 - 0.00058 19.4 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAG00680.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 OAG00680.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4523 PF15023.6 OAG00680.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Nuc_deoxyri_tr2 PF15891.5 OAG00682.1 - 1.5e-28 99.2 0.0 2.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like zf-Sec23_Sec24 PF04810.15 OAG00683.1 - 0.49 10.5 5.0 0.15 12.2 1.4 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Peptidase_S8 PF00082.22 OAG00686.1 - 7.5e-41 140.3 0.7 1.3e-40 139.5 0.7 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAG00686.1 - 5.4e-12 46.4 0.1 1.3e-11 45.2 0.0 1.7 2 0 0 2 2 2 1 Fn3-like domain NAD_binding_10 PF13460.6 OAG00687.1 - 1.7e-08 34.6 0.3 2.7e-08 33.9 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG00687.1 - 2.3e-07 30.6 0.1 2.7e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAG00687.1 - 0.0028 17.1 0.2 0.043 13.3 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_hydro_106 PF17132.4 OAG00689.1 - 1.2e-16 60.2 3.5 2e-16 59.5 1.2 2.1 2 0 0 2 2 2 1 alpha-L-rhamnosidase BrkDBD PF09607.10 OAG00689.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain Glyco_hydro_2_C PF02836.17 OAG00690.1 - 1.3e-99 333.2 0.0 1.8e-99 332.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 OAG00690.1 - 1.3e-61 208.3 0.0 2.1e-61 207.6 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 OAG00690.1 - 2e-46 158.0 1.7 4.4e-46 156.9 1.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 OAG00690.1 - 9e-16 58.1 0.2 5.5e-15 55.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 OAG00690.1 - 1.3e-10 41.9 0.0 4.2e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OAG00690.1 - 0.0085 16.7 0.0 0.03 14.9 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain HAD PF12710.7 OAG00691.1 - 0.00014 22.3 1.1 0.0025 18.2 1.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG00691.1 - 0.076 13.3 0.6 2.4 8.4 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 OAG00692.1 - 3.5e-86 289.8 22.4 4.3e-86 289.6 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00692.1 - 2e-39 135.5 49.7 1.3e-32 113.1 23.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG00692.1 - 0.0024 16.4 1.7 0.0024 16.4 1.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3792 PF12670.7 OAG00692.1 - 0.0093 16.1 3.0 0.0093 16.1 3.0 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF3792) LacY_symp PF01306.19 OAG00692.1 - 0.9 8.2 17.3 8.4 5.1 13.3 2.4 2 1 0 2 2 2 0 LacY proton/sugar symporter AA_permease PF00324.21 OAG00696.1 - 1.1e-137 459.5 38.7 1.3e-137 459.3 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG00696.1 - 2.7e-38 131.9 42.8 4e-38 131.4 42.8 1.2 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.24 OAG00698.1 - 5.9e-31 108.3 0.0 8.1e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG00698.1 - 3.2e-07 30.5 0.0 0.024 14.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG00698.1 - 0.00011 21.5 0.2 0.0037 16.5 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG00698.1 - 0.00015 21.9 0.1 0.00077 19.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG00698.1 - 0.00018 20.7 0.1 0.00085 18.5 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG00698.1 - 0.0047 15.8 0.0 0.3 9.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 OAG00698.1 - 0.011 16.0 0.0 2.5 8.4 0.0 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 OAG00698.1 - 0.063 12.6 0.0 0.51 9.6 0.0 2.1 2 1 0 2 2 2 0 ThiF family Pyr_redox_3 PF13738.6 OAG00698.1 - 0.1 11.8 0.1 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 OAG00699.1 - 4.9e-12 46.4 7.7 8.8e-10 39.1 1.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ERp29_N PF07912.13 OAG00699.1 - 0.031 14.4 0.0 0.085 13.0 0.0 1.7 2 0 0 2 2 2 0 ERp29, N-terminal domain Fungal_trans PF04082.18 OAG00700.1 - 2.8e-19 69.2 0.1 4.8e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG00700.1 - 0.00059 19.9 16.6 0.0011 19.0 16.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAG00701.1 - 1.6e-18 67.5 1.2 2.3e-18 66.9 1.2 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4905 PF16248.5 OAG00701.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) MASE3 PF17159.4 OAG00703.1 - 0.023 14.3 1.9 0.03 13.9 1.9 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain Glyco_hydro_35 PF01301.19 OAG00704.1 - 4.3e-89 299.3 0.0 5.2e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OAG00704.1 - 2.4e-08 33.7 0.1 4.9e-08 32.7 0.1 1.5 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 OAG00704.1 - 6.4e-05 23.5 0.0 0.00068 20.2 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain CHB_HEX_C_1 PF13290.6 OAG00704.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain HET PF06985.11 OAG00709.1 - 2e-34 119.0 0.2 3.8e-34 118.1 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF664 PF04978.12 OAG00709.1 - 0.0035 17.8 1.1 4 7.9 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF664) APG6_N PF17675.1 OAG00709.1 - 0.13 12.8 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FAD_binding_4 PF01565.23 OAG00710.1 - 0.0003 20.5 0.2 0.00043 20.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain DIOX_N PF14226.6 OAG00711.1 - 3.1e-32 111.8 0.0 4.6e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG00711.1 - 5.8e-15 55.6 0.1 1.3e-14 54.5 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3602 PF12223.8 OAG00712.1 - 2.1e-17 63.5 14.4 8e-15 55.2 1.7 3.1 2 2 1 3 3 3 2 Protein of unknown function (DUF3602) Peptidase_M50B PF13398.6 OAG00714.1 - 2.8e-59 200.1 16.8 3.6e-59 199.8 16.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 OAG00714.1 - 0.0044 16.3 0.1 0.011 15.0 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M50 MLANA PF14991.6 OAG00714.1 - 3.4 8.0 7.7 0.29 11.4 0.9 2.3 1 1 1 2 2 2 0 Protein melan-A YlaC PF10777.9 OAG00714.1 - 6.7 6.5 6.0 0.47 10.3 0.7 1.7 2 0 0 2 2 2 0 Inner membrane protein YlaC DUF4191 PF13829.6 OAG00714.1 - 7.8 5.8 8.5 3.2 7.0 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Sugar_tr PF00083.24 OAG00715.1 - 5.6e-125 417.7 22.1 6.5e-125 417.5 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00715.1 - 8.9e-21 74.2 61.9 1.2e-17 63.9 30.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF347 PF03988.12 OAG00715.1 - 0.32 11.2 7.9 0.18 12.0 2.0 3.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) FMN_dh PF01070.18 OAG00716.1 - 1.9e-110 369.2 0.0 2.1e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG00716.1 - 4.4e-05 22.8 0.1 6.6e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG00716.1 - 0.00011 21.3 0.2 0.00029 19.9 0.2 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 OAG00716.1 - 0.00059 19.2 0.2 0.38 10.0 0.1 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 OAG00716.1 - 0.001 18.5 0.7 0.0016 17.9 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAG00716.1 - 0.054 12.9 0.1 0.31 10.5 0.1 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein adh_short_C2 PF13561.6 OAG00717.1 - 1.5e-54 185.0 0.0 2.1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG00717.1 - 6.4e-46 156.3 0.1 7.8e-46 156.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG00717.1 - 3.4e-11 43.4 0.2 5.1e-11 42.8 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 OAG00717.1 - 0.00036 20.9 0.2 0.00058 20.3 0.2 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 OAG00717.1 - 0.0013 18.6 0.2 0.002 18.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAG00717.1 - 0.0029 16.8 0.0 0.0037 16.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MTS PF05175.14 OAG00717.1 - 0.016 14.8 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Pyr_redox PF00070.27 OAG00717.1 - 0.041 14.4 0.2 0.11 13.1 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4303 PF14136.6 OAG00717.1 - 0.05 13.3 0.1 0.48 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Sugar_tr PF00083.24 OAG00718.1 - 6.6e-76 256.0 28.7 1.6e-74 251.4 28.7 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00718.1 - 5.9e-12 45.2 43.0 2.1e-11 43.3 35.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Esterase PF00756.20 OAG00719.1 - 2.6e-07 30.5 0.0 3.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 OAG00719.1 - 0.0034 16.7 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG00719.1 - 0.0039 16.7 0.0 0.0066 15.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG00719.1 - 0.076 13.6 0.0 0.083 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family TRI12 PF06609.13 OAG00721.1 - 2.3e-76 257.5 16.9 2.9e-76 257.2 16.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG00721.1 - 1.6e-21 76.6 50.4 7.8e-20 71.1 51.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG00721.1 - 4.1e-10 39.1 4.2 4.1e-10 39.1 4.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter HeLo PF14479.6 OAG00722.1 - 2.7e-34 118.8 0.0 4.6e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF2226 PF09987.9 OAG00722.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) CPSase_L_D2 PF02786.17 OAG00723.1 - 5.1e-81 271.2 0.1 8.4e-81 270.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OAG00723.1 - 1.1e-69 234.1 0.0 2e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OAG00723.1 - 6.7e-37 126.4 0.1 1.4e-36 125.4 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG00723.1 - 7.4e-30 103.2 0.0 1.9e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OAG00723.1 - 3.8e-29 102.1 0.0 8.6e-29 100.9 0.0 1.6 1 1 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OAG00723.1 - 5.4e-19 67.8 1.9 1.3e-18 66.6 1.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAG00723.1 - 1.7e-10 40.6 0.6 2.1e-05 24.2 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 OAG00723.1 - 1.1e-09 38.1 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG00723.1 - 6.7e-08 32.3 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG00723.1 - 5.2e-05 23.3 0.0 0.00017 21.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OAG00723.1 - 0.00057 19.5 0.0 0.0019 17.8 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 OAG00723.1 - 0.0012 18.1 0.1 0.21 10.8 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 OAG00723.1 - 0.0023 17.5 0.0 0.008 15.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 OAG00723.1 - 0.0032 18.2 0.1 0.84 10.4 0.0 3.1 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 OAG00723.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 OAG00723.1 - 0.15 11.3 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp AZUL PF16558.5 OAG00724.1 - 0.054 13.7 1.2 0.11 12.8 0.4 1.9 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Pec_lyase_C PF00544.19 OAG00725.1 - 6.3e-15 55.3 10.9 2.1e-13 50.4 10.9 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG00725.1 - 0.0003 20.7 19.2 0.057 13.3 7.1 2.6 1 1 1 2 2 2 2 Right handed beta helix region Clathrin PF00637.20 OAG00726.1 - 9e-195 638.4 26.3 9.2e-32 109.9 2.3 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OAG00726.1 - 4.3e-31 106.6 1.0 4.3e-31 106.6 1.0 3.1 3 1 1 4 4 4 1 Clathrin-H-link Clathrin_propel PF01394.20 OAG00726.1 - 5.4e-14 51.7 0.4 1.1e-05 25.4 0.0 5.5 5 0 0 5 5 5 2 Clathrin propeller repeat TPR_14 PF13428.6 OAG00726.1 - 9.2e-05 23.0 7.2 1.8 9.6 0.1 7.8 10 0 0 10 10 8 1 Tetratricopeptide repeat Vps39_1 PF10366.9 OAG00726.1 - 0.00036 20.8 10.4 6.6 7.1 0.0 6.2 5 1 0 5 5 5 3 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.14 OAG00726.1 - 0.002 17.2 0.7 0.23 10.5 0.4 3.6 3 0 0 3 3 3 1 Coatomer WD associated region TPR_7 PF13176.6 OAG00726.1 - 0.043 13.8 2.9 89 3.5 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG00726.1 - 0.076 12.9 1.6 6.7 6.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG00726.1 - 0.08 13.2 7.2 0.38 11.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG00726.1 - 0.16 12.2 4.7 7.9 6.9 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG00726.1 - 2.5 8.5 6.2 36 4.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 OAG00727.1 - 2.7e-76 256.7 29.3 3e-76 256.5 29.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PIEZO PF15917.5 OAG00727.1 - 7.1 6.0 13.4 2.1 7.8 8.2 2.0 2 0 0 2 2 2 0 Piezo DnaJ PF00226.31 OAG00729.1 - 1.7e-08 34.4 0.0 4.9e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain EMC3_TMCO1 PF01956.16 OAG00729.1 - 3.4 7.4 8.6 2.8 7.7 5.9 1.9 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like XPB_DRD PF18458.1 OAG00730.1 - 0.11 12.4 0.7 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain zf-H2C2_2 PF13465.6 OAG00731.1 - 3.7e-14 52.4 24.9 2.9e-08 33.8 2.8 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG00731.1 - 4.2e-10 39.5 23.0 0.0032 17.8 3.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG00731.1 - 1e-07 32.2 20.2 0.05 14.4 2.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG00731.1 - 2.8e-05 24.0 16.5 0.014 15.4 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 OAG00731.1 - 0.0021 17.8 1.7 5.2 7.0 0.2 3.3 2 1 1 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 OAG00731.1 - 0.0029 17.8 10.4 0.009 16.3 6.8 2.6 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OAG00731.1 - 0.0031 17.7 4.7 1.9 8.9 1.8 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding FAM184 PF15665.5 OAG00731.1 - 0.0052 16.6 2.5 0.0084 15.9 2.5 1.3 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B GAGA PF09237.11 OAG00731.1 - 0.017 14.9 1.2 0.017 14.9 1.2 3.4 1 1 2 3 3 3 0 GAGA factor zf-C2HC_2 PF13913.6 OAG00731.1 - 0.033 14.1 0.8 0.033 14.1 0.8 3.3 4 0 0 4 4 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 OAG00731.1 - 0.036 14.2 9.1 0.041 14.0 4.1 2.6 1 1 2 3 3 3 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 OAG00731.1 - 0.072 12.9 10.0 0.64 9.9 0.9 3.4 2 1 1 3 3 3 0 Rad50 zinc hook motif zinc_ribbon_9 PF14369.6 OAG00731.1 - 0.086 13.1 4.0 25 5.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-CHCC PF10276.9 OAG00731.1 - 0.1 12.7 6.5 5.5 7.1 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger domain FYVE PF01363.21 OAG00731.1 - 0.12 12.5 5.7 0.33 11.1 0.6 2.4 2 0 0 2 2 2 0 FYVE zinc finger FYDLN_acid PF09538.10 OAG00731.1 - 0.16 12.7 6.7 0.11 13.2 1.0 3.0 2 1 1 3 3 2 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 OAG00731.1 - 0.31 11.1 2.5 1.1 9.3 2.5 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OAG00731.1 - 0.47 10.5 8.9 6.4 6.9 9.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-ISL3 PF14690.6 OAG00731.1 - 0.81 10.4 10.9 3 8.6 0.5 3.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_2 PF12756.7 OAG00731.1 - 2 8.8 9.7 8.8 6.7 1.3 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 OAG00731.1 - 3 7.8 12.8 14 5.7 0.4 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 OAG00731.1 - 4.7 7.3 5.5 31 4.7 5.5 2.2 1 1 0 1 1 1 0 zinc-ribbons zf-ribbon_3 PF13248.6 OAG00731.1 - 5.8 6.5 6.3 13 5.3 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.12 OAG00731.1 - 6.6 7.1 7.8 64 3.9 7.5 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain zf-LITAF-like PF10601.9 OAG00731.1 - 7.8 6.9 7.6 34 4.8 0.1 3.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Pkinase PF00069.25 OAG00732.1 - 8.4e-68 228.6 0.0 1.2e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00732.1 - 4.9e-51 173.5 0.0 7.3e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG00732.1 - 0.0018 17.1 0.0 0.0036 16.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAG00732.1 - 0.15 11.4 0.0 0.62 9.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OAG00732.1 - 0.2 10.5 0.0 0.6 9.0 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain SOG2 PF10428.9 OAG00732.1 - 9.7 5.3 19.8 15 4.6 19.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CorA PF01544.18 OAG00733.1 - 3e-07 30.1 8.4 3.5e-07 29.8 6.0 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein AA_permease_2 PF13520.6 OAG00734.1 - 2.3e-07 30.0 3.9 3.7e-07 29.3 3.9 1.4 1 0 0 1 1 1 1 Amino acid permease H_PPase PF03030.16 OAG00734.1 - 0.12 11.0 0.2 0.73 8.4 0.0 1.9 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase CYYR1 PF10873.8 OAG00734.1 - 0.22 12.0 2.3 12 6.3 0.7 2.5 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 EamA PF00892.20 OAG00734.1 - 7.2 6.8 13.3 0.041 14.0 2.8 2.4 3 0 0 3 3 3 0 EamA-like transporter family LSDAT_euk PF18139.1 OAG00736.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 SLOG in TRPM Pkinase PF00069.25 OAG00737.1 - 1.3e-09 37.8 0.0 5.5e-09 35.8 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain CorA PF01544.18 OAG00738.1 - 1.4e-30 106.7 10.9 1.6e-22 80.2 2.5 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Mito_fiss_reg PF05308.11 OAG00738.1 - 0.0011 19.2 0.1 0.0024 18.0 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial fission regulator Peptidase_U4 PF03419.13 OAG00738.1 - 0.087 12.1 0.6 0.14 11.5 0.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA AA_permease_2 PF13520.6 OAG00739.1 - 7.9e-45 153.4 46.0 9.9e-45 153.1 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG00739.1 - 1.4e-20 73.3 39.8 3.2e-20 72.2 39.8 1.5 1 1 0 1 1 1 1 Amino acid permease LysM PF01476.20 OAG00744.1 - 2.8e-16 59.3 0.1 0.00023 21.1 0.0 3.4 3 0 0 3 3 3 3 LysM domain Peptidase_C36 PF05415.11 OAG00744.1 - 0.035 14.3 0.0 20 5.5 0.0 3.1 3 0 0 3 3 3 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Ad_Cy_reg PF16701.5 OAG00744.1 - 0.29 10.8 0.0 28 4.4 0.0 2.8 3 0 0 3 3 3 0 Adenylate cyclase regulatory domain Aspzincin_M35 PF14521.6 OAG00745.1 - 0.013 16.1 0.4 0.033 14.8 0.4 1.7 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Glyco_hydro_18 PF00704.28 OAG00746.1 - 4.7e-21 75.8 2.2 2.1e-11 44.1 0.4 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 LysM PF01476.20 OAG00746.1 - 8.3e-08 32.2 0.0 0.0068 16.4 0.0 2.9 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 OAG00746.1 - 7.3e-05 23.2 10.9 7.3e-05 23.2 10.9 4.1 4 1 0 4 4 4 1 Chitin recognition protein zf-H2C2_2 PF13465.6 OAG00746.1 - 9.2 6.9 6.2 8.8 7.0 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.25 OAG00747.1 - 5.1e-34 117.8 0.0 8.6e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00747.1 - 7.8e-19 68.0 0.0 1.7e-18 66.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_4 PF13637.6 OAG00747.1 - 7.4e-06 26.4 0.2 1 10.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG00747.1 - 4.4e-05 23.5 1.4 1.1 10.0 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OAG00747.1 - 5.6e-05 23.6 0.0 0.33 11.6 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG00747.1 - 0.00057 20.1 0.2 1.1 9.7 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG00747.1 - 0.38 11.3 4.8 6.7 7.3 0.2 4.0 4 0 0 4 4 4 0 Ankyrin repeat S1-P1_nuclease PF02265.16 OAG00748.1 - 6.7e-58 196.5 0.0 7.7e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease ADH_N PF08240.12 OAG00749.1 - 4.7e-33 113.3 1.2 6.1e-33 113.0 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG00749.1 - 2e-24 86.1 0.8 2.4e-24 85.7 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG00749.1 - 1.5e-10 41.0 0.1 2.5e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG00749.1 - 0.00017 21.0 0.3 0.00029 20.2 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG00749.1 - 0.00034 21.7 0.0 0.00065 20.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG00749.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 OAG00749.1 - 0.0038 16.5 0.1 0.04 13.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG00749.1 - 0.12 11.0 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein MTS PF05175.14 OAG00749.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AdoHcyase_NAD PF00670.21 OAG00749.1 - 0.16 12.0 1.6 1.1 9.3 1.6 2.2 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_16 PF10294.9 OAG00750.1 - 7.7e-20 71.3 0.0 1e-18 67.7 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG00750.1 - 6.6e-09 35.8 0.0 9.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG00750.1 - 0.039 14.6 0.0 0.11 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF2773 PF10971.8 OAG00750.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) MTS PF05175.14 OAG00750.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain VPS28 PF03997.12 OAG00751.1 - 3.6e-70 235.5 0.1 4.2e-70 235.3 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein NDC10_II PF16787.5 OAG00751.1 - 0.02 14.0 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Noc2 PF03715.13 OAG00752.1 - 8.5e-129 429.1 0.0 8.5e-129 429.1 0.0 1.8 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 OAG00752.1 - 0.0016 16.8 0.1 0.0016 16.8 0.1 3.4 2 2 0 3 3 3 1 Nop14-like family GFA PF04828.14 OAG00753.1 - 3.7e-11 43.2 16.2 1.8e-06 28.2 6.3 3.6 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme TPR_10 PF13374.6 OAG00754.1 - 5e-12 45.3 12.9 2e-06 27.4 0.1 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG00754.1 - 1.8e-11 44.2 1.7 4.9e-09 36.4 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG00754.1 - 8.9e-11 41.4 0.4 1.7e-10 40.5 0.4 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAG00754.1 - 5.3e-10 39.9 6.6 1.4e-08 35.3 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain HET PF06985.11 OAG00754.1 - 2.4e-09 37.7 17.4 3.9e-09 37.0 1.7 3.6 3 2 1 4 4 4 2 Heterokaryon incompatibility protein (HET) AAA_22 PF13401.6 OAG00754.1 - 2.8e-07 30.9 0.6 2.1e-06 28.0 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 OAG00754.1 - 4.3e-06 27.2 0.0 7.3e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG00754.1 - 6.5e-05 22.9 1.3 0.00013 21.9 0.1 2.1 2 1 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 OAG00754.1 - 0.00021 21.3 0.0 0.00066 19.7 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea TniB PF05621.11 OAG00754.1 - 0.00024 20.6 0.0 0.00056 19.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein AAA_33 PF13671.6 OAG00754.1 - 0.0034 17.5 1.0 0.076 13.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAG00754.1 - 0.0062 16.3 0.0 0.023 14.5 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein SRP54 PF00448.22 OAG00754.1 - 0.016 14.8 0.3 0.059 13.0 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 OAG00754.1 - 0.085 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AntA PF08346.12 OAG00754.1 - 0.091 13.3 0.4 0.42 11.2 0.2 2.1 2 0 0 2 2 2 0 AntA/AntB antirepressor FAD_binding_8 PF08022.12 OAG00757.1 - 5.4e-24 84.4 0.0 1.2e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG00757.1 - 2.1e-21 76.6 0.0 3.5e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAG00757.1 - 8.2e-19 67.9 11.5 8.2e-19 67.9 11.5 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Glyco_hydro_43 PF04616.14 OAG00758.1 - 3.7e-11 42.9 1.1 6.1e-11 42.2 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AMPK1_CBM PF16561.5 OAG00759.1 - 3.5e-05 23.9 0.0 7.5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Carboxyl_trans PF01039.22 OAG00759.1 - 0.2 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain ADIP PF11559.8 OAG00761.1 - 4e-45 153.6 11.7 4e-45 153.6 11.7 2.7 3 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 OAG00761.1 - 0.00024 20.7 8.8 0.00024 20.7 8.8 2.2 2 0 0 2 2 2 1 Golgin subfamily A member 5 RepA_C PF04796.12 OAG00761.1 - 0.051 13.6 0.4 0.1 12.6 0.4 1.6 1 0 0 1 1 1 0 Plasmid encoded RepA protein Jnk-SapK_ap_N PF09744.9 OAG00761.1 - 3 8.0 15.4 4 7.7 7.6 3.0 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 OAG00761.1 - 5.3 7.2 7.5 28 4.9 5.7 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PTPLA PF04387.14 OAG00762.1 - 2.5e-47 160.7 13.3 4.2e-47 159.9 13.3 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Glyoxalase PF00903.25 OAG00763.1 - 4.2e-09 36.7 3.1 4.2e-08 33.5 1.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UDG PF03167.19 OAG00764.1 - 2.3e-18 66.6 0.0 3.2e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily WW PF00397.26 OAG00765.1 - 1.2e-12 47.7 1.7 2.6e-12 46.6 1.7 1.7 1 0 0 1 1 1 1 WW domain HATPase_c PF02518.26 OAG00767.1 - 1.4e-22 80.3 0.0 2.8e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG00767.1 - 9.3e-22 77.3 0.1 2e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAG00767.1 - 4.4e-07 30.1 0.6 2.1e-05 24.7 0.0 3.2 3 0 0 3 3 2 1 PAS fold HisKA PF00512.25 OAG00767.1 - 8.4e-07 28.9 2.3 1.2e-06 28.5 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 OAG00767.1 - 1.9e-05 24.9 0.0 0.00072 19.8 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 OAG00767.1 - 7.6e-05 22.6 0.0 0.00026 20.9 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 OAG00767.1 - 0.00028 21.1 0.1 0.00067 19.9 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAG00767.1 - 0.0014 18.6 5.3 0.0027 17.7 0.0 3.2 3 0 0 3 3 2 1 PAS fold GAF_2 PF13185.6 OAG00767.1 - 0.015 15.6 0.0 0.094 13.0 0.0 2.4 1 1 1 2 2 2 0 GAF domain Spt20 PF12090.8 OAG00767.1 - 0.87 9.2 15.9 1.5 8.4 15.9 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OAG00767.1 - 1.5 8.7 16.6 2.8 7.9 16.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 OAG00767.1 - 2.3 7.6 13.9 5.7 6.3 13.9 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Clr5 PF14420.6 OAG00768.1 - 9.6e-14 51.3 1.1 5.2e-13 49.0 0.5 2.5 2 0 0 2 2 2 1 Clr5 domain UbiA PF01040.18 OAG00769.1 - 3.3e-37 128.2 14.1 4.4e-37 127.7 13.9 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family MIP PF00230.20 OAG00770.1 - 2.5e-47 161.5 15.7 3.3e-47 161.1 15.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein tRNA-synt_2 PF00152.20 OAG00771.1 - 4.8e-57 193.4 0.0 6.9e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 OAG00771.1 - 1.3e-07 31.4 0.0 9.9e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 OAG00771.1 - 5.2e-07 29.6 0.1 9.9e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF5316 PF17247.2 OAG00772.1 - 0.056 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5316) BAAT_C PF08840.11 OAG00774.1 - 0.0055 16.6 0.0 0.0068 16.4 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OAG00774.1 - 0.16 11.5 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Ank_2 PF12796.7 OAG00775.1 - 0.00017 22.1 0.0 0.012 16.2 0.0 3.2 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG00775.1 - 0.00046 20.4 0.0 0.24 12.1 0.0 4.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 OAG00775.1 - 0.0023 18.2 0.0 0.25 11.7 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG00775.1 - 0.034 14.7 0.0 21 5.9 0.0 3.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.30 OAG00775.1 - 0.069 13.6 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Glyco_tranf_2_3 PF13641.6 OAG00777.1 - 3.5e-27 95.8 0.0 5.3e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG00777.1 - 4.4e-09 36.4 0.0 8.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG00777.1 - 4.7e-06 26.2 0.0 0.00011 21.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Amidohydro_2 PF04909.14 OAG00779.1 - 7.4e-21 75.2 0.8 1.5e-19 70.9 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase adh_short_C2 PF13561.6 OAG00780.1 - 9.8e-60 202.0 0.1 1.3e-59 201.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG00780.1 - 1.7e-40 138.6 0.8 3.2e-40 137.7 0.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG00780.1 - 8.6e-12 45.3 0.8 1.3e-11 44.8 0.8 1.2 1 0 0 1 1 1 1 KR domain DEAD PF00270.29 OAG00781.1 - 1.8e-29 102.8 0.0 9.3e-28 97.2 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG00781.1 - 1.2e-22 80.3 0.0 1.5e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG00781.1 - 5.8e-08 32.9 0.0 9.7e-07 28.9 0.0 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit ATP-synt_G PF04718.15 OAG00782.1 - 1.9e-33 115.3 0.9 4.3e-33 114.1 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit SEP PF08059.13 OAG00783.1 - 0.12 12.9 0.3 0.58 10.8 0.0 2.1 2 0 0 2 2 2 0 SEP domain ARTD15_N PF18084.1 OAG00784.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 ARTD15 N-terminal domain MFS_1 PF07690.16 OAG00785.1 - 1.6e-36 126.0 28.6 1.6e-36 126.0 28.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 OAG00785.1 - 0.024 14.9 0.0 0.024 14.9 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) ADH_N PF08240.12 OAG00787.1 - 1e-28 99.4 0.1 2.2e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG00787.1 - 1e-15 57.8 0.1 2.3e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG00787.1 - 6.9e-05 22.4 0.3 0.00015 21.4 0.3 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 OAG00787.1 - 0.0036 16.6 0.1 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG00787.1 - 0.0037 17.8 0.2 0.2 12.2 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAG00787.1 - 0.0057 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 OAG00787.1 - 0.0061 17.6 0.0 0.015 16.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG00787.1 - 0.026 13.8 0.1 0.074 12.3 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAG00787.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ubiquitin PF00240.23 OAG00788.1 - 7.1e-20 70.5 0.0 1.3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OAG00788.1 - 1.4e-08 34.4 0.4 3.4e-08 33.2 0.4 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 OAG00788.1 - 3.7e-07 29.9 0.0 6.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG00788.1 - 1.7e-05 25.3 0.0 3.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG00788.1 - 0.00025 21.1 0.1 0.00052 20.1 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 OAG00788.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair YukD PF08817.10 OAG00788.1 - 0.021 15.5 0.1 0.069 13.8 0.1 1.9 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD STI1 PF17830.1 OAG00788.1 - 0.043 13.7 20.1 0.52 10.3 4.7 2.7 1 1 1 2 2 2 0 STI1 domain GerD PF17898.1 OAG00788.1 - 0.94 9.5 7.6 0.77 9.7 5.5 1.8 1 1 1 2 2 2 0 Spore germination GerD central core domain DUF2477 PF10631.9 OAG00788.1 - 1.3 9.7 2.8 2.5 8.8 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2477) ADH_zinc_N PF00107.26 OAG00789.1 - 4e-33 114.2 0.5 6.9e-33 113.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG00789.1 - 8.3e-12 46.3 0.0 1.3e-11 45.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG00789.1 - 1.1e-06 28.4 0.0 6.1e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 OAG00789.1 - 0.0012 19.1 0.1 0.002 18.3 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OAG00789.1 - 0.01 15.2 0.4 0.016 14.5 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh PF00389.30 OAG00790.1 - 0.045 13.4 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CLTH PF10607.9 OAG00791.1 - 4.2e-36 124.1 0.1 6.2e-36 123.5 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 OAG00791.1 - 8.4e-22 77.5 0.1 1.6e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 OAG00791.1 - 0.00028 20.7 1.5 0.00051 19.9 0.1 2.3 3 0 0 3 3 3 1 LisH INO80_Ies4 PF08193.11 OAG00792.1 - 3.7e-57 194.1 18.2 3.7e-57 194.1 18.2 1.4 1 1 1 2 2 2 2 INO80 complex subunit Ies4 DUF3331 PF11811.8 OAG00793.1 - 0.0047 16.8 1.3 0.0069 16.2 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3331) DUF3484 PF11983.8 OAG00794.1 - 1.9 9.6 5.9 4.7 8.4 6.0 1.7 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Rep_fac_C PF08542.11 OAG00796.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Replication factor C C-terminal domain Pro_isomerase PF00160.21 OAG00797.1 - 1.1e-34 120.0 0.0 1.7e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OAG00797.1 - 2.3e-14 53.0 0.0 4.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG00797.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb2_6 PF00562.28 OAG00798.1 - 4e-124 414.6 0.1 7e-124 413.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG00798.1 - 6.3e-59 198.9 0.0 9.7e-59 198.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAG00798.1 - 7.2e-40 136.7 0.0 1.9e-39 135.3 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAG00798.1 - 5.7e-33 113.2 0.1 1.4e-32 111.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OAG00798.1 - 1.3e-25 89.3 0.1 3.1e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OAG00798.1 - 1.6e-22 79.6 0.1 4.2e-22 78.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OAG00798.1 - 3.5e-20 72.3 0.2 3.5e-20 72.3 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 PQQ_3 PF13570.6 OAG00799.1 - 0.064 13.8 3.3 0.14 12.7 1.1 2.7 3 0 0 3 3 3 0 PQQ-like domain HET PF06985.11 OAG00801.1 - 6.5e-17 62.2 0.0 1.3e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ThiF PF00899.21 OAG00802.1 - 1.6e-58 198.0 0.0 2.5e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OAG00802.1 - 4.2e-07 30.5 0.1 1.1e-06 29.1 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Spc24 PF08286.11 OAG00802.1 - 0.014 15.6 0.7 0.031 14.5 0.2 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NAD_binding_7 PF13241.6 OAG00802.1 - 0.023 15.1 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FlxA PF14282.6 OAG00802.1 - 0.049 13.6 3.0 0.1 12.6 3.0 1.5 1 0 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.8 OAG00802.1 - 0.13 12.3 0.3 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Shikimate_DH PF01488.20 OAG00802.1 - 0.13 12.3 0.3 0.37 10.9 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Csm1_N PF18504.1 OAG00802.1 - 0.46 10.9 2.7 1.1 9.7 2.7 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain ZapB PF06005.12 OAG00802.1 - 0.5 10.9 2.8 0.98 9.9 2.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB PRKG1_interact PF15898.5 OAG00802.1 - 0.54 11.2 2.6 0.85 10.6 0.7 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1996 PF09362.10 OAG00803.1 - 2.2e-84 283.1 1.5 3.2e-84 282.6 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Peptidase_M16 PF00675.20 OAG00804.1 - 7.7e-58 194.7 0.1 4.6e-57 192.2 0.1 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAG00804.1 - 3e-38 131.7 0.0 3.1e-37 128.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.12 OAG00805.1 - 3.8e-52 175.5 0.0 4.9e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF2205 PF10224.9 OAG00806.1 - 3.2e-31 107.1 0.0 5.4e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Short coiled-coil protein His_Phos_2 PF00328.22 OAG00807.1 - 2.3e-40 139.1 0.0 2.8e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AP3D1 PF06375.11 OAG00808.1 - 0.0027 17.9 1.2 0.0041 17.4 1.2 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Gemini_AL2 PF01440.16 OAG00808.1 - 0.1 13.0 2.4 0.16 12.4 2.4 1.3 1 0 0 1 1 1 0 Geminivirus AL2 protein SR-25 PF10500.9 OAG00808.1 - 6.4 6.3 13.9 9.3 5.8 13.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PP2C PF00481.21 OAG00809.1 - 2.3e-36 125.8 0.0 3.9e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Glyco_transf_22 PF03901.17 OAG00810.1 - 0.41 9.8 2.7 0.57 9.3 2.7 1.1 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family SLX9 PF15341.6 OAG00811.1 - 1e-32 113.3 11.9 1e-32 113.3 11.9 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 PAF-AH_p_II PF03403.13 OAG00812.1 - 1.8e-52 178.1 0.0 5.2e-29 100.9 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG00812.1 - 6.4e-07 28.5 0.0 3.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG00812.1 - 0.00038 19.8 0.0 0.73 9.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OAG00812.1 - 0.005 15.9 0.0 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase TFIIA PF03153.13 OAG00814.1 - 7.4e-71 240.3 62.5 1.9e-61 209.4 54.0 2.3 2 1 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Endostatin PF06482.11 OAG00814.1 - 0.18 11.2 14.4 0.29 10.6 14.4 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Exonuc_VII_L PF02601.15 OAG00814.1 - 0.66 9.5 15.9 0.96 9.0 15.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GREB1 PF15782.5 OAG00814.1 - 1.1 6.3 19.0 1.5 5.8 19.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 OAG00814.1 - 1.4 8.0 17.3 1.7 7.7 17.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_S64 PF08192.11 OAG00814.1 - 5.3 5.4 13.6 6.8 5.0 13.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 OAG00814.1 - 7.2 4.7 46.6 11 4.1 46.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 OAG00814.1 - 7.5 4.6 18.0 11 4.0 18.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rad1 PF02144.16 OAG00815.1 - 6.1e-85 284.6 0.0 7e-85 284.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PRIMA1 PF16101.5 OAG00815.1 - 0.0053 16.8 2.7 0.011 15.8 2.7 1.5 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Ost5 PF05251.12 OAG00816.1 - 1.3e-20 73.4 8.0 1.6e-20 73.1 8.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 CorA PF01544.18 OAG00816.1 - 0.49 9.7 5.6 0.54 9.5 5.6 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Bromodomain PF00439.25 OAG00817.1 - 8e-23 80.3 1.0 1.9e-22 79.1 1.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OAG00817.1 - 6.3e-08 32.9 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG00817.1 - 6.4e-07 29.4 0.2 1.6e-06 28.1 0.2 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG00817.1 - 0.0005 20.4 0.1 0.00093 19.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG00817.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Abhydrolase_6 PF12697.7 OAG00818.1 - 3.6e-20 73.5 0.2 4.1e-20 73.3 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 OAG00818.1 - 0.024 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) CLTH PF10607.9 OAG00819.1 - 3.7e-29 101.5 0.0 6.4e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OAG00819.1 - 5.9e-08 32.6 0.2 1.1e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG00819.1 - 0.0019 18.5 0.4 0.0034 17.7 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG00819.1 - 0.0063 16.5 0.2 0.011 15.6 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Rtf2 PF04641.12 OAG00819.1 - 0.0081 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 OAG00819.1 - 0.016 15.0 0.8 0.031 14.1 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG00819.1 - 0.022 14.6 0.8 0.041 13.8 0.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG00819.1 - 0.062 13.2 0.4 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG00819.1 - 0.071 13.0 0.5 0.14 12.1 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG00819.1 - 0.12 12.6 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1664 PF07889.12 OAG00820.1 - 0.0023 18.0 0.2 0.0054 16.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) PG_binding_1 PF01471.18 OAG00820.1 - 0.0068 16.6 0.1 1.9 8.7 0.0 3.4 2 1 0 2 2 2 1 Putative peptidoglycan binding domain BLOC1_2 PF10046.9 OAG00820.1 - 0.0075 16.5 0.8 0.019 15.2 0.8 1.7 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 OAG00820.1 - 0.022 14.9 0.2 0.022 14.9 0.2 2.0 3 0 0 3 3 3 0 Tropomyosin like FlaC_arch PF05377.11 OAG00820.1 - 0.066 13.6 1.0 0.17 12.3 1.0 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Myosin_tail_1 PF01576.19 OAG00820.1 - 0.11 10.3 0.9 0.18 9.6 0.9 1.2 1 0 0 1 1 1 0 Myosin tail Tropomyosin PF00261.20 OAG00820.1 - 0.19 11.1 2.5 0.12 11.8 0.4 1.6 2 0 0 2 2 2 0 Tropomyosin Chlorophyllase2 PF12740.7 OAG00821.1 - 5.3e-06 25.5 0.0 7.6e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG00821.1 - 0.019 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase COesterase PF00135.28 OAG00821.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family PAF-AH_p_II PF03403.13 OAG00821.1 - 0.18 10.3 0.1 0.88 8.0 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II zf-C2H2_2 PF12756.7 OAG00822.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AI-2E_transport PF01594.16 OAG00822.1 - 0.26 10.4 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 AI-2E family transporter FAM176 PF14851.6 OAG00823.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Nucleos_tra2_C PF07662.13 OAG00824.1 - 6e-70 235.3 0.4 6e-70 235.3 0.4 2.6 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OAG00824.1 - 8.3e-23 80.8 4.2 8.3e-23 80.8 4.2 3.3 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus SSF PF00474.17 OAG00825.1 - 2.8e-19 69.3 31.0 4e-19 68.8 31.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Ibs_toxin PF13956.6 OAG00825.1 - 0.028 14.4 2.3 0.08 13.0 2.3 1.9 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system MRAP PF15183.6 OAG00825.1 - 7.6 6.6 15.6 1.3 9.0 1.0 4.4 4 0 0 4 4 4 0 Melanocortin-2 receptor accessory protein family NAD_binding_10 PF13460.6 OAG00826.1 - 0.0055 16.6 0.0 0.0078 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding F-box-like PF12937.7 OAG00829.1 - 0.051 13.5 0.6 0.25 11.3 0.0 2.5 3 0 0 3 3 3 0 F-box-like Tli4_C PF18426.1 OAG00830.1 - 0.062 13.6 0.0 0.26 11.6 0.0 2.1 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain FAD-oxidase_C PF02913.19 OAG00833.1 - 2.8e-61 207.3 0.0 4.3e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG00833.1 - 8.8e-39 132.4 0.0 3.1e-37 127.4 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain SPRY PF00622.28 OAG00834.1 - 9.7e-05 22.5 0.0 0.00056 20.0 0.0 2.4 1 1 0 1 1 1 1 SPRY domain Sugar_tr PF00083.24 OAG00836.1 - 3.2e-74 250.4 28.7 3.6e-74 250.2 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00836.1 - 4.2e-11 42.4 40.6 4.2e-11 42.4 40.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 OAG00837.1 - 2.3e-22 79.3 0.0 3.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG00837.1 - 1.8e-17 63.2 0.0 3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAG00837.1 - 1.3e-05 26.2 0.0 2.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF469 PF04320.14 OAG00837.1 - 0.2 12.5 0.0 10 7.1 0.0 2.6 3 0 0 3 3 3 0 Protein with unknown function (DUF469) Maf PF02545.14 OAG00838.1 - 5.6e-46 156.4 0.0 6.8e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Gly-zipper_Omp PF13488.6 OAG00839.1 - 0.067 13.2 4.2 0.2 11.7 4.2 1.7 1 0 0 1 1 1 0 Glycine zipper Scytalone_dh PF02982.14 OAG00841.1 - 4.7e-84 280.0 0.7 5.4e-84 279.8 0.7 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 OAG00841.1 - 2e-10 40.9 0.2 2.6e-10 40.5 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain LPD23 PF18838.1 OAG00841.1 - 0.0092 15.7 1.1 0.022 14.5 1.1 1.6 1 0 0 1 1 1 1 Large polyvalent protein associated domain 23 RRM_1 PF00076.22 OAG00842.1 - 5.8e-46 154.2 0.0 7.6e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG00842.1 - 2.9e-06 27.0 0.0 0.057 13.3 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG00842.1 - 4.3e-05 23.4 0.1 0.0015 18.4 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG00842.1 - 0.0001 22.3 0.0 0.0012 18.8 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 OAG00842.1 - 0.00089 19.3 0.6 0.051 13.7 0.0 3.1 3 1 0 3 3 3 1 RNA recognition motif PHM7_cyt PF14703.6 OAG00842.1 - 0.02 15.2 0.1 2 8.6 0.0 3.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 OAG00842.1 - 0.022 14.3 0.0 0.093 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fer4_23 PF18009.1 OAG00843.1 - 0.084 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron-sulfur cluster binding domain Flexi_CP_N PF08358.10 OAG00843.1 - 0.15 12.0 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 Carlavirus coat DAO PF01266.24 OAG00844.1 - 1.3e-30 107.2 0.1 1.7e-30 106.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Zn_clus PF00172.18 OAG00845.1 - 4.1e-08 33.2 9.0 6.7e-08 32.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG00845.1 - 0.0068 15.5 0.2 0.014 14.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CobS_N PF12556.8 OAG00845.1 - 0.043 13.5 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Cobaltochelatase CobS subunit N terminal Pyrophosphatase PF00719.19 OAG00847.1 - 1.9e-41 141.5 0.1 3e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase ADH_zinc_N PF00107.26 OAG00848.1 - 3.4e-13 49.7 0.1 5.7e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG00848.1 - 8.8e-10 38.4 0.2 5.2e-09 35.9 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG00848.1 - 0.076 14.1 0.0 0.13 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase OrsD PF12013.8 OAG00849.1 - 2.9e-28 98.6 0.1 5.1e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 OAG00849.1 - 0.13 11.9 0.1 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type Fungal_trans_2 PF11951.8 OAG00849.1 - 0.13 11.1 0.0 0.32 9.8 0.0 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF1664 PF07889.12 OAG00850.1 - 0.017 15.2 0.1 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NAD_binding_1 PF00175.21 OAG00851.1 - 1.1e-33 116.1 0.0 1.8e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG00851.1 - 4.3e-23 81.5 0.0 1e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAG00851.1 - 9.5e-08 32.3 0.0 0.00038 20.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAG00851.1 - 0.0017 18.6 0.0 0.0045 17.2 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain GFA PF04828.14 OAG00852.1 - 4.9e-09 36.4 0.2 4.9e-09 36.4 0.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribonuclease PF00545.20 OAG00855.1 - 0.12 13.1 0.0 0.34 11.7 0.0 1.7 1 0 0 1 1 1 0 ribonuclease TPR_10 PF13374.6 OAG00856.1 - 6e-30 102.3 5.0 6.8e-10 38.5 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG00856.1 - 4.2e-28 97.5 11.7 1.7e-16 60.3 2.6 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG00856.1 - 6.5e-14 51.1 9.7 7e-05 22.5 0.7 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat HET PF06985.11 OAG00856.1 - 1.7e-13 51.2 7.9 9.6e-12 45.5 1.0 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_8 PF13181.6 OAG00856.1 - 3.9e-11 42.2 8.7 0.042 14.1 0.2 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG00856.1 - 1.5e-10 41.0 2.7 7.6e-06 25.5 0.8 2.4 1 1 1 2 2 2 2 MalT-like TPR region NB-ARC PF00931.22 OAG00856.1 - 7e-10 38.5 0.1 3.8e-09 36.1 0.1 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 OAG00856.1 - 2.6e-09 36.5 10.7 0.0066 16.5 0.3 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG00856.1 - 2.7e-09 36.4 4.6 0.034 14.2 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG00856.1 - 2.3e-07 31.0 2.6 0.48 11.4 0.2 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAG00856.1 - 1e-06 29.3 0.1 4.5e-06 27.2 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain TPR_21 PF09976.9 OAG00856.1 - 9.1e-06 25.5 8.4 0.44 10.2 0.2 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 OAG00856.1 - 1.4e-05 25.3 0.0 0.84 10.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 OAG00856.1 - 8.1e-05 22.4 0.9 1.2 8.8 0.0 3.4 1 1 2 3 3 3 2 26S proteasome subunit RPN7 TPR_17 PF13431.6 OAG00856.1 - 8.9e-05 22.6 4.5 2.7 8.6 0.2 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat ATPase_2 PF01637.18 OAG00856.1 - 0.00019 21.4 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_16 PF13432.6 OAG00856.1 - 0.00054 20.6 12.8 0.17 12.6 0.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG00856.1 - 0.012 16.1 7.7 1 9.9 0.8 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NACHT PF05729.12 OAG00856.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TPR_11 PF13414.6 OAG00856.1 - 0.02 14.6 11.4 0.42 10.3 0.8 3.8 3 0 0 3 3 3 0 TPR repeat DUF2225 PF09986.9 OAG00856.1 - 0.02 14.6 0.2 0.99 9.1 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.20 OAG00856.1 - 0.14 12.5 0.1 48 4.5 0.0 3.5 2 0 0 2 2 2 0 PPR repeat Amidohydro_1 PF01979.20 OAG00859.1 - 2.4e-18 66.6 0.1 5.5e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OAG00859.1 - 3.7e-10 39.9 0.0 7.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Glyco_transf_90 PF05686.12 OAG00860.1 - 1.8e-29 102.9 1.1 2.2e-29 102.6 1.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OAG00860.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Sulfate_transp PF00916.20 OAG00861.1 - 4.4e-110 368.0 20.6 5.6e-110 367.7 20.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG00861.1 - 1.3e-08 34.5 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OAG00861.1 - 9.2e-05 22.8 4.3 9.2e-05 22.8 4.3 3.2 3 2 0 3 3 3 2 Molybdate transporter of MFS superfamily Zn_clus PF00172.18 OAG00863.1 - 4e-08 33.2 9.0 7.2e-08 32.4 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 OAG00863.1 - 7.1e-07 29.0 15.4 7.1e-07 29.0 15.4 2.4 2 1 0 2 2 2 1 Aflatoxin regulatory protein Aldo_ket_red PF00248.21 OAG00864.1 - 6.6e-54 183.1 0.0 8e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AtuA PF07287.11 OAG00865.1 - 3.1e-128 427.4 0.3 3.8e-128 427.1 0.3 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA TRIF-NTD PF17798.1 OAG00865.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 TRIF N-terminal domain Zn_clus PF00172.18 OAG00866.1 - 1.9e-14 53.5 33.8 2.2e-07 30.8 11.5 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG00866.1 - 2.3e-07 30.1 0.0 3.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAG00867.1 - 3.3e-109 365.7 29.9 3.8e-109 365.6 29.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG00867.1 - 7.1e-20 71.2 38.6 2.2e-18 66.3 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG00867.1 - 0.0021 16.7 5.3 0.0021 16.7 5.3 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_45 PF02015.16 OAG00868.1 - 3e-78 262.6 19.2 3.5e-78 262.3 19.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Sipho_Gp157 PF05565.11 OAG00869.1 - 0.034 14.2 2.1 0.056 13.4 2.1 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 SKA2 PF16740.5 OAG00869.1 - 0.065 13.0 2.8 0.1 12.4 2.8 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 CorA PF01544.18 OAG00869.1 - 0.61 9.3 4.1 1.3 8.3 4.1 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 OAG00870.1 - 1.4e-59 201.8 52.4 3.4e-45 154.5 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG00870.1 - 2.2e-05 22.9 8.2 0.006 14.9 2.0 3.2 2 2 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 OAG00870.1 - 0.00036 19.1 20.0 0.0006 18.3 8.4 2.6 2 1 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 OAG00870.1 - 0.0034 16.3 8.3 0.0034 16.3 8.3 4.2 2 2 1 3 3 3 2 MFS_1 like family DUF1500 PF07389.12 OAG00870.1 - 0.061 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Fringe PF02434.16 OAG00871.1 - 2.4e-07 30.5 0.1 3.8e-06 26.5 0.1 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OAG00871.1 - 0.031 14.1 0.0 1 9.1 0.0 2.3 1 1 1 2 2 2 0 Galactosyltransferase PAN_4 PF14295.6 OAG00871.1 - 0.046 13.6 1.1 0.097 12.6 1.1 1.5 1 0 0 1 1 1 0 PAN domain RPA43_OB PF17875.1 OAG00872.1 - 0.043 14.4 0.1 0.1 13.2 0.1 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I SH3_9 PF14604.6 OAG00873.1 - 3.9e-14 52.2 0.1 8.1e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG00873.1 - 6.9e-11 41.6 0.1 1.6e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 OAG00873.1 - 7.1e-10 38.9 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 OAG00873.1 - 7.2e-10 39.3 0.0 5.3e-09 36.5 0.0 2.5 2 1 0 2 2 2 1 PH domain SH3_2 PF07653.17 OAG00873.1 - 0.00036 20.1 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 OAG00873.1 - 0.00044 20.6 0.0 0.0014 19.0 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 OAG00873.1 - 0.006 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_PNT PF02198.16 OAG00873.1 - 0.015 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PH_8 PF15409.6 OAG00873.1 - 0.049 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain zf-MIZ PF02891.20 OAG00874.1 - 5.7e-12 45.2 0.3 1.1e-11 44.3 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger CFEM PF05730.11 OAG00878.1 - 9.4e-15 54.5 15.4 9.4e-15 54.5 15.4 1.8 2 0 0 2 2 2 1 CFEM domain p450 PF00067.22 OAG00879.1 - 7.8e-45 153.5 0.0 1e-44 153.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4745 PF15923.5 OAG00879.1 - 0.048 13.7 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) DUF4851 PF16143.5 OAG00881.1 - 0.6 9.5 4.5 0.53 9.7 2.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4851) FPN1 PF06963.12 OAG00882.1 - 1.6e-118 396.1 17.0 2.4e-118 395.4 17.0 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) adh_short PF00106.25 OAG00884.1 - 7.4e-32 110.4 0.0 1.7e-31 109.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00884.1 - 2.3e-24 86.2 0.0 3.8e-24 85.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00884.1 - 1.8e-13 50.8 0.0 2.2e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG00884.1 - 1.6e-08 34.3 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG00884.1 - 1.8e-07 30.9 0.0 2.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG00884.1 - 1.4e-06 27.7 0.3 2.3e-06 27.0 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG00884.1 - 0.00011 22.2 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG00884.1 - 0.009 15.1 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF2263 PF10021.9 OAG00884.1 - 0.011 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) 3Beta_HSD PF01073.19 OAG00884.1 - 0.046 12.7 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAG00884.1 - 0.047 13.2 0.3 0.081 12.5 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family zf-C2H2_4 PF13894.6 OAG00885.1 - 6.9e-05 23.4 12.1 0.033 15.0 0.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAG00885.1 - 0.00011 22.4 1.3 0.045 13.9 0.1 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 OAG00885.1 - 0.00015 22.0 11.6 0.047 14.2 1.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG00885.1 - 0.088 13.3 10.9 0.11 13.0 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG00885.1 - 0.43 10.9 5.4 4.8 7.6 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FAD_binding_4 PF01565.23 OAG00888.1 - 3.6e-12 46.2 0.0 6.4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 OAG00889.1 - 5.5e-28 97.9 44.9 5.5e-28 97.9 44.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG00889.1 - 0.00012 21.1 41.6 0.00014 20.9 9.2 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter RTA1 PF04479.13 OAG00890.1 - 1.3e-55 188.3 15.0 2e-55 187.7 15.0 1.3 1 0 0 1 1 1 1 RTA1 like protein SP_C-Propep PF08999.10 OAG00890.1 - 0.21 11.4 1.1 0.69 9.7 0.1 2.3 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide CTNNBL PF08216.11 OAG00891.1 - 4.2e-37 126.5 0.2 1.2e-36 125.0 0.2 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.6 OAG00891.1 - 0.0025 18.2 1.6 0.17 12.3 0.2 3.0 2 0 0 2 2 2 1 HEAT repeats SEN1_N PF12726.7 OAG00891.1 - 0.0039 15.5 1.0 0.094 10.9 0.2 2.6 3 0 0 3 3 3 1 SEN1 N terminal Mo25 PF08569.11 OAG00891.1 - 0.0056 16.1 0.4 0.021 14.2 0.1 1.9 2 1 1 3 3 3 1 Mo25-like KIX_2 PF16987.5 OAG00891.1 - 0.14 12.2 2.2 0.16 11.9 0.2 2.1 3 0 0 3 3 3 0 KIX domain AcetylCoA_hydro PF02550.15 OAG00893.1 - 7.4e-49 166.4 0.0 1.1e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 OAG00893.1 - 4.4e-42 143.6 0.0 8.1e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 OAG00893.1 - 0.087 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Coenzyme A transferase zf-C3HC4_3 PF13920.6 OAG00894.1 - 0.6 10.0 6.8 0.95 9.4 6.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 OAG00895.1 - 0.03 14.4 8.8 0.87 9.8 3.9 2.3 1 1 1 2 2 2 0 FYVE zinc finger RloB PF13707.6 OAG00895.1 - 0.15 12.2 5.1 0.43 10.8 5.0 1.7 1 1 0 1 1 1 0 RloB-like protein Zn-ribbon_8 PF09723.10 OAG00895.1 - 0.28 11.3 7.5 0.23 11.6 2.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-TFIIB PF13453.6 OAG00895.1 - 0.45 9.9 3.0 0.82 9.1 3.0 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger AtuA PF07287.11 OAG00896.1 - 1.1e-119 399.2 0.0 1.5e-119 398.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FAD_binding_4 PF01565.23 OAG00897.1 - 9.4e-22 77.2 0.6 1.6e-21 76.5 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain GST_C_3 PF14497.6 OAG00898.1 - 1.7e-06 28.1 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG00898.1 - 1.8e-06 28.1 0.0 5.2e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG00898.1 - 2e-06 28.0 0.1 7.5e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG00898.1 - 1.2e-05 25.6 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG00898.1 - 2.4e-05 24.3 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG00898.1 - 8.6e-05 22.9 0.0 0.00019 21.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Avl9 PF09794.9 OAG00899.1 - 3.8e-141 470.2 0.0 4.4e-141 470.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 OAG00899.1 - 9e-08 32.1 0.1 0.00011 22.1 0.0 2.5 1 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 OAG00899.1 - 1.2e-06 28.3 1.2 0.0022 17.6 1.2 3.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 OAG00899.1 - 0.031 14.2 0.4 0.18 11.8 0.2 2.1 2 1 0 2 2 2 0 DENN (AEX-3) domain Pkinase PF00069.25 OAG00900.1 - 3.7e-68 229.7 0.0 4.9e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG00900.1 - 1e-31 110.2 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG00900.1 - 8.6e-06 24.9 0.1 1.1e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG00900.1 - 6.2e-05 22.4 0.1 0.00021 20.7 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG00900.1 - 0.00057 19.9 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG00900.1 - 0.0046 16.3 0.0 0.071 12.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 OAG00900.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAG00900.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.20 OAG00902.1 - 1.2e-115 386.5 0.0 1.4e-115 386.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG00902.1 - 1.5e-15 57.1 1.6 8.1e-11 41.7 0.2 2.8 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG00902.1 - 4.4e-05 23.0 0.2 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG00902.1 - 0.0023 18.2 0.2 0.51 10.6 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 OAG00902.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 OAG00902.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 OAG00902.1 - 0.14 11.6 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 OAG00902.1 - 0.44 10.1 1.3 3.8 7.0 0.0 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OAG00904.1 - 6.8e-46 156.2 0.1 2.5e-27 96.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG00904.1 - 1.7e-26 93.5 32.0 1.2e-16 61.2 9.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG00904.1 - 1.8e-08 34.1 7.5 0.046 13.1 0.0 4.5 3 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG00904.1 - 8.1e-08 32.4 0.5 0.88 9.3 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG00904.1 - 8.4e-06 25.8 0.3 0.19 11.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAG00904.1 - 1.1e-05 25.7 0.3 0.27 11.5 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 OAG00904.1 - 2e-05 24.2 1.0 0.15 11.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAG00904.1 - 5.3e-05 23.3 0.1 0.34 11.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG00904.1 - 0.00026 21.4 0.6 0.77 10.1 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OAG00904.1 - 0.00041 19.8 0.3 0.25 10.7 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family NB-ARC PF00931.22 OAG00904.1 - 0.0012 18.1 0.7 0.1 11.8 0.2 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 OAG00904.1 - 0.0026 17.3 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 OAG00904.1 - 0.0057 16.6 0.4 1.5 8.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 OAG00904.1 - 0.0077 16.4 0.2 2.5 8.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain cobW PF02492.19 OAG00904.1 - 0.0096 15.5 0.9 1.5 8.4 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 OAG00904.1 - 0.01 15.9 0.7 0.38 10.8 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OAG00904.1 - 0.017 15.6 0.3 7.2 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 OAG00904.1 - 0.02 14.2 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Septin MeaB PF03308.16 OAG00904.1 - 0.033 13.2 0.1 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OAG00904.1 - 0.041 14.0 1.6 3.6 7.6 0.2 2.5 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 OAG00904.1 - 0.043 14.0 0.2 12 6.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 OAG00904.1 - 0.088 11.8 0.1 3.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 OAG00904.1 - 0.096 12.4 2.9 25 4.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 OAG00904.1 - 0.11 11.6 0.1 4 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) COesterase PF00135.28 OAG00906.1 - 1.1e-91 308.2 0.0 1.3e-91 308.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG00906.1 - 0.0003 20.7 0.4 0.00074 19.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold AAA_12 PF13087.6 OAG00907.1 - 1.2e-39 136.0 0.1 2.5e-39 135.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG00907.1 - 3.6e-24 85.9 0.1 9.8e-24 84.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG00907.1 - 6.4e-08 33.1 0.1 7.5e-07 29.6 0.0 2.8 3 1 0 3 3 3 1 AAA domain DUF2075 PF09848.9 OAG00907.1 - 2.6e-07 30.2 1.1 0.0015 17.8 0.0 2.8 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.24 OAG00907.1 - 3.7e-07 29.9 5.2 1.2e-06 28.3 5.2 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAG00907.1 - 4.2e-07 29.6 3.8 2e-06 27.4 3.8 2.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAG00907.1 - 6.2e-07 29.3 6.6 2.1e-06 27.6 6.6 2.0 1 0 0 1 1 1 1 Zinc finger domain AAA_30 PF13604.6 OAG00907.1 - 3.9e-05 23.4 0.3 0.0058 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain HAUS2 PF15003.6 OAG00907.1 - 0.063 13.0 1.5 0.14 11.8 0.7 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 ResIII PF04851.15 OAG00907.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HET PF06985.11 OAG00908.1 - 7.6e-33 113.9 0.7 9.2e-32 110.4 0.7 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_GPO PF05929.11 OAG00908.1 - 0.23 11.0 0.0 0.59 9.7 0.0 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF756 PF05506.12 OAG00909.1 - 0.066 14.1 0.1 0.2 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF756) Ank_2 PF12796.7 OAG00910.1 - 4.9e-11 43.1 0.7 5.1e-05 23.8 0.1 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG00910.1 - 1.5e-09 38.2 0.3 0.00035 21.1 0.0 3.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG00910.1 - 2.2e-09 37.3 2.0 0.092 13.2 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OAG00910.1 - 1.4e-08 34.3 3.5 0.055 14.0 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAG00910.1 - 2.8e-06 27.5 1.1 0.092 13.1 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 OAG00910.1 - 0.00035 20.4 0.2 0.0082 16.0 0.2 2.6 1 1 0 1 1 1 1 KilA-N domain Spc42p PF11544.8 OAG00910.1 - 0.015 15.2 1.9 0.033 14.2 0.1 2.3 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF4795 PF16043.5 OAG00910.1 - 0.088 12.4 4.3 4.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF874 PF05917.11 OAG00910.1 - 0.16 11.0 2.4 0.28 10.2 2.4 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) KxDL PF10241.9 OAG00910.1 - 2.9 8.2 7.3 18 5.7 2.9 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Complex1_LYR PF05347.15 OAG00911.1 - 6.1e-07 29.4 2.0 1.9e-06 27.8 2.0 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG00911.1 - 0.089 13.5 2.2 0.3 11.9 0.8 2.3 2 1 0 2 2 2 0 Complex1_LYR-like Acetyltransf_1 PF00583.25 OAG00912.1 - 1.4e-16 60.8 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG00912.1 - 2.3e-09 37.5 0.0 3.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG00912.1 - 2.5e-08 33.9 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG00912.1 - 2.4e-06 27.4 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAG00912.1 - 0.00019 22.1 0.0 0.00023 21.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG00912.1 - 0.0023 18.1 0.0 0.0033 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAG00912.1 - 0.0027 17.3 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 OAG00912.1 - 0.0054 16.8 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 OAG00912.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Pec_lyase_C PF00544.19 OAG00913.1 - 7.2e-16 58.4 11.3 2.6e-14 53.3 11.3 2.2 1 1 0 1 1 1 1 Pectate lyase DUF3530 PF12048.8 OAG00914.1 - 0.16 11.3 6.1 0.29 10.5 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) AAA PF00004.29 OAG00915.1 - 5.9e-12 46.2 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG00915.1 - 8.9e-07 29.0 0.3 1.2e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 OAG00915.1 - 1e-05 25.6 0.0 2.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG00915.1 - 2.1e-05 24.3 0.0 5.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG00915.1 - 2.2e-05 24.8 0.0 7.5e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG00915.1 - 0.0023 18.3 0.0 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAG00915.1 - 0.0063 16.7 0.5 0.026 14.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG00915.1 - 0.0075 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 OAG00915.1 - 0.016 14.9 5.7 0.098 12.4 0.2 3.0 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 OAG00915.1 - 0.019 14.9 0.3 0.043 13.7 0.3 1.6 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 OAG00915.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAG00915.1 - 0.034 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 OAG00915.1 - 0.074 13.6 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG00915.1 - 0.085 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 OAG00915.1 - 0.1 11.7 0.0 0.67 9.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 OAG00915.1 - 0.11 13.0 0.1 0.42 11.1 0.1 1.9 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 OAG00915.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 OAG00915.1 - 0.15 11.9 0.0 4.5 7.1 0.0 2.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Cytochrom_B561 PF03188.16 OAG00916.1 - 2.9 8.0 9.1 4.8 7.3 7.2 2.2 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 RR_TM4-6 PF06459.12 OAG00917.1 - 1.9 8.2 9.8 0.6 9.9 6.7 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TGF_beta PF00019.20 OAG00919.1 - 0.026 15.5 0.1 5.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Transforming growth factor beta like domain DUF4618 PF15397.6 OAG00919.1 - 0.07 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CCD48 PF15799.5 OAG00919.1 - 0.099 10.9 0.1 0.099 10.9 0.1 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 bZIP_1 PF00170.21 OAG00919.1 - 0.21 11.7 0.1 0.41 10.8 0.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor ketoacyl-synt PF00109.26 OAG00921.1 - 1e-75 254.6 0.0 2.8e-75 253.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG00921.1 - 9.7e-41 140.3 0.0 2.6e-40 138.9 0.1 1.6 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.10 OAG00921.1 - 1.4e-38 132.6 0.0 5.4e-38 130.7 0.0 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 OAG00921.1 - 1.4e-35 123.0 0.0 2.4e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 OAG00921.1 - 1.4e-31 108.9 0.1 3.1e-31 107.8 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAG00921.1 - 2.9e-14 53.4 0.0 7e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OAG00921.1 - 0.00074 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 OAG00921.1 - 0.00076 18.9 0.2 0.0023 17.4 0.2 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 OAG00921.1 - 0.029 14.7 0.0 0.085 13.2 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Mito_carr PF00153.27 OAG00922.1 - 1.2e-58 195.0 4.1 9e-19 67.2 1.4 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein MGC-24 PF05283.11 OAG00922.1 - 1.8 9.0 4.6 3.1 8.2 4.6 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Rho_N PF07498.12 OAG00923.1 - 0.061 13.3 0.8 0.14 12.2 0.8 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain FAD_binding_3 PF01494.19 OAG00924.1 - 3.5e-20 72.5 0.1 1e-19 71.0 0.1 1.8 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 OAG00924.1 - 4.8e-14 52.7 2.0 4.6e-06 26.4 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG00924.1 - 8.2e-07 28.5 0.1 0.007 15.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG00924.1 - 4.1e-06 26.1 0.0 8e-06 25.1 0.0 1.4 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 OAG00924.1 - 1.4e-05 25.2 1.6 3.5e-05 24.0 1.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG00924.1 - 3.4e-05 24.3 0.2 0.067 13.8 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG00924.1 - 0.00022 20.5 3.0 0.00037 19.7 3.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG00924.1 - 0.00034 19.4 0.6 0.0018 17.0 0.9 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG00924.1 - 0.0039 16.6 1.4 0.0069 15.8 1.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OAG00924.1 - 0.054 13.4 0.3 0.089 12.7 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAG00924.1 - 0.061 12.4 1.2 0.1 11.6 1.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG00924.1 - 0.079 12.2 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG00924.1 - 0.15 10.9 0.6 0.36 9.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 OAG00924.1 - 0.15 11.3 1.3 2.4 7.3 0.5 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Zn_clus PF00172.18 OAG00925.1 - 0.00043 20.3 10.0 0.0013 18.8 10.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.27 OAG00926.1 - 2.1e-34 118.8 0.0 1e-33 116.5 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAG00926.1 - 4.2e-17 62.2 0.1 1.2e-16 60.8 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OAG00926.1 - 2.7e-10 40.5 0.1 2.7e-10 40.5 0.1 3.8 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 OAG00926.1 - 9.7e-09 35.0 0.3 4e-08 33.0 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 OAG00926.1 - 6.5e-07 29.4 0.1 9.9e-06 25.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OAG00926.1 - 0.00041 20.2 0.0 0.0017 18.2 0.0 2.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Roc PF08477.13 OAG00926.1 - 0.0018 18.4 0.0 0.0051 17.0 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TrkA_C PF02080.21 OAG00926.1 - 0.026 14.3 0.6 0.93 9.4 0.0 2.8 3 0 0 3 3 3 0 TrkA-C domain Chitin_synth_2 PF03142.15 OAG00927.1 - 7.3e-244 810.3 1.0 9.5e-244 809.9 1.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 OAG00927.1 - 2.3e-77 260.8 0.0 1.2e-76 258.4 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 OAG00927.1 - 9.1e-19 67.1 0.4 8e-18 64.1 0.3 2.5 3 0 0 3 3 3 1 DEK C terminal domain Cyt-b5 PF00173.28 OAG00927.1 - 2.6e-16 59.5 0.4 3.6e-14 52.6 0.0 2.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 OAG00927.1 - 1.8e-12 47.6 0.6 2.1e-10 40.9 0.1 2.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG00927.1 - 5.9e-12 45.9 4.8 5.9e-12 45.9 4.8 2.4 3 0 0 3 3 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG00927.1 - 6.4e-05 22.8 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_22 PF13401.6 OAG00927.1 - 0.067 13.5 0.1 0.26 11.6 0.1 2.0 1 0 0 1 1 1 0 AAA domain Glyco_hydro_16 PF00722.21 OAG00927.1 - 0.095 12.2 0.4 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Glyco_transf_21 PF13506.6 OAG00927.1 - 0.16 11.5 0.2 0.74 9.3 0.2 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 21 AAA_30 PF13604.6 OAG00927.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain Chitin_synth_2 PF03142.15 OAG00928.1 - 1.9e-230 766.0 0.1 3e-230 765.3 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 OAG00928.1 - 1.4e-14 53.8 0.2 1.1e-13 50.9 0.5 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 OAG00928.1 - 2.4e-13 50.0 0.3 3.9e-07 30.1 0.0 3.3 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 OAG00928.1 - 2.2e-12 47.3 0.0 6.5e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG00928.1 - 3.8e-12 46.5 2.4 3.8e-12 46.5 2.4 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Myosin_head PF00063.21 OAG00928.1 - 5.2e-10 38.2 0.0 8.9e-10 37.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 OAG00928.1 - 0.0002 20.9 0.0 0.00047 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG00928.1 - 0.002 17.9 0.0 0.062 13.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Disaggr_repeat PF06848.11 OAG00928.1 - 0.077 12.7 0.5 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 Disaggregatase related repeat End3 PF12761.7 OAG00929.1 - 2.2e-66 223.8 0.0 2.9e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 OAG00929.1 - 7.5e-50 167.2 0.0 4.7e-49 164.7 0.1 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 OAG00929.1 - 6.4e-08 32.9 0.1 5.1e-07 30.0 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG00929.1 - 9.8e-08 31.0 0.2 9.8e-08 31.0 0.2 2.0 2 0 0 2 2 1 1 EF hand EF-hand_6 PF13405.6 OAG00929.1 - 8.7e-05 22.2 0.3 0.00035 20.3 0.3 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 OAG00929.1 - 0.00012 21.9 0.1 0.00024 20.9 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAG00929.1 - 0.0014 18.1 0.1 0.0042 16.5 0.1 1.9 1 0 0 1 1 1 1 EF hand Phage_GP20 PF06810.11 OAG00929.1 - 0.025 14.4 0.4 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Med9 PF07544.13 OAG00929.1 - 0.092 12.8 0.1 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Rx_N PF18052.1 OAG00929.1 - 0.53 10.6 2.7 1.6 9.0 0.2 2.3 2 0 0 2 2 2 0 Rx N-terminal domain TSC22 PF01166.18 OAG00929.1 - 0.85 10.0 5.5 12 6.3 0.2 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family Bap31_Bap29_C PF18035.1 OAG00929.1 - 1.1 9.3 3.8 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Oxidored_FMN PF00724.20 OAG00930.1 - 1.9e-67 228.0 0.0 2.3e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Zn_clus PF00172.18 OAG00931.1 - 2.4e-05 24.3 8.0 2.4e-05 24.3 8.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ada3 PF10198.9 OAG00935.1 - 0.14 12.3 0.4 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Solute_trans_a PF03619.16 OAG00936.1 - 5.1e-97 324.5 13.7 6.2e-97 324.3 13.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HET PF06985.11 OAG00938.1 - 2e-21 76.8 0.0 4.5e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Herpes_UL42 PF02282.16 OAG00939.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) FYVE PF01363.21 OAG00941.1 - 1.2e-20 73.4 27.3 2.2e-16 59.7 7.2 3.1 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 OAG00941.1 - 2.3e-18 65.7 1.8 6.5e-18 64.2 1.8 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain YqaH PF17448.2 OAG00941.1 - 0.0063 16.8 0.2 0.014 15.6 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized YqaH-like zf-AN1 PF01428.16 OAG00941.1 - 0.0092 16.1 3.3 0.0092 16.1 3.3 4.2 5 1 1 6 6 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 OAG00941.1 - 0.022 15.1 0.1 0.022 15.1 0.1 3.2 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding OrsD PF12013.8 OAG00941.1 - 0.082 13.4 2.7 1.5 9.3 0.0 3.8 4 0 0 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D Allexi_40kDa PF05549.11 OAG00941.1 - 0.12 11.8 3.5 5.3 6.5 0.6 3.1 3 0 0 3 3 3 0 Allexivirus 40kDa protein Cob_adeno_trans PF01923.18 OAG00941.1 - 0.19 11.9 4.8 0.36 10.9 0.4 3.1 4 0 0 4 4 4 0 Cobalamin adenosyltransferase C6_DPF PF10170.9 OAG00941.1 - 0.42 11.0 5.5 0.5 10.8 0.9 2.8 2 0 0 2 2 2 0 Cysteine-rich domain CtIP_N PF10482.9 OAG00941.1 - 0.92 9.6 11.9 2.3 8.3 0.0 3.6 3 1 1 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain Val_tRNA-synt_C PF10458.9 OAG00941.1 - 2 8.8 5.9 25 5.2 0.0 3.5 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm HypA PF01155.19 OAG00941.1 - 2 8.4 13.3 0.23 11.5 0.2 3.8 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 OAG00941.1 - 4.3 8.5 34.8 2 9.5 0.0 6.3 6 1 1 7 7 6 0 C2H2-type zinc finger Seryl_tRNA_N PF02403.22 OAG00941.1 - 7.8 6.8 9.1 0.27 11.5 1.9 2.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Rad50_zn_hook PF04423.14 OAG00941.1 - 7.8 6.4 9.2 18 5.3 0.0 5.0 5 0 0 5 5 5 0 Rad50 zinc hook motif NAD_binding_7 PF13241.6 OAG00942.1 - 3.4e-32 111.0 0.1 5.3e-32 110.4 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAG00942.1 - 9.1e-29 98.9 0.0 1.4e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 OAG00942.1 - 3.6e-14 51.9 0.1 3.6e-14 51.9 0.1 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 OAG00942.1 - 0.0004 20.4 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase LSDAT_prok PF18171.1 OAG00942.1 - 0.0027 17.0 0.1 0.0038 16.5 0.1 1.2 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote TrkA_N PF02254.18 OAG00942.1 - 0.033 14.4 0.6 0.097 12.9 0.6 1.7 1 1 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAG00942.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_10 PF05971.12 OAG00943.1 - 4e-52 177.4 0.0 5.6e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 OAG00943.1 - 1.7e-05 24.4 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OAG00943.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 OAG00943.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF5549 PF17703.1 OAG00943.1 - 0.17 11.6 0.2 0.28 10.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) FAD_binding_4 PF01565.23 OAG00945.1 - 1.5e-16 60.4 1.4 2.9e-16 59.5 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG00945.1 - 3.2e-10 39.9 0.0 6.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Exo_endo_phos PF03372.23 OAG00946.1 - 3.2e-05 23.6 0.0 6.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA_anti-codon PF01336.25 OAG00946.1 - 0.087 12.8 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MFS_1 PF07690.16 OAG00948.1 - 9.3e-36 123.5 21.3 9.3e-36 123.5 21.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SNF2_N PF00176.23 OAG00949.1 - 2.2e-71 240.4 0.0 3.4e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG00949.1 - 1.3e-12 48.0 0.0 4.9e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG00949.1 - 0.00062 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HIRAN PF08797.11 OAG00949.1 - 0.017 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 HIRAN domain Prok-RING_4 PF14447.6 OAG00949.1 - 0.027 14.3 1.8 0.087 12.7 1.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG00949.1 - 0.081 12.9 4.4 0.16 11.9 4.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain OLF PF02191.16 OAG00949.1 - 0.21 11.1 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Olfactomedin-like domain PI3_PI4_kinase PF00454.27 OAG00950.1 - 2.7e-41 142.1 0.0 4.7e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DASH_Ask1 PF08655.10 OAG00951.1 - 7.5e-31 105.8 0.1 1.1e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 SBF2 PF12335.8 OAG00951.1 - 0.17 11.4 0.2 0.24 11.0 0.2 1.2 1 0 0 1 1 1 0 Myotubularin protein DUF908 PF06012.12 OAG00951.1 - 8.8 5.6 8.5 2.4 7.5 3.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) adh_short PF00106.25 OAG00952.1 - 1.8e-53 181.0 2.2 2.1e-53 180.7 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00952.1 - 4.8e-52 176.8 3.8 8.2e-52 176.1 3.8 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00952.1 - 1.9e-11 44.2 0.9 3.6e-11 43.3 0.9 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG00952.1 - 0.001 18.6 0.3 0.0052 16.3 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ATP_bind_2 PF03668.15 OAG00952.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family fn3 PF00041.21 OAG00953.1 - 0.048 14.0 0.1 0.088 13.2 0.1 1.4 1 0 0 1 1 1 0 Fibronectin type III domain Nop14 PF04147.12 OAG00954.1 - 5.1 5.2 9.6 6.1 4.9 9.6 1.0 1 0 0 1 1 1 0 Nop14-like family GYF PF02213.16 OAG00955.1 - 3.8e-17 61.7 0.2 7.8e-17 60.7 0.2 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OAG00955.1 - 0.00086 19.1 0.1 0.0031 17.3 0.1 2.0 1 0 0 1 1 1 1 GYF domain 2 Homeodomain PF00046.29 OAG00955.1 - 0.29 11.0 3.1 0.73 9.7 3.1 1.6 1 0 0 1 1 1 0 Homeodomain zf-RING_2 PF13639.6 OAG00956.1 - 3.6e-13 49.6 19.2 1e-12 48.1 10.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OAG00956.1 - 1.3e-10 40.9 4.7 1.3e-10 40.9 4.7 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OAG00956.1 - 1.5e-08 34.4 11.9 4.4e-07 29.7 4.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG00956.1 - 5.2e-07 29.4 9.9 5.2e-07 29.4 9.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG00956.1 - 6.4e-07 29.1 18.0 7.4e-06 25.7 9.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 OAG00956.1 - 4.3e-06 26.9 11.3 0.00029 21.0 5.4 2.7 2 0 0 2 2 2 2 zinc-ribbon zf-RING_5 PF14634.6 OAG00956.1 - 5.2e-06 26.3 6.8 5.2e-06 26.3 6.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAG00956.1 - 6e-06 26.4 10.8 6e-06 26.4 10.8 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG00956.1 - 0.00042 20.3 4.0 0.00042 20.3 4.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OAG00956.1 - 0.00077 19.3 13.7 0.0056 16.5 6.9 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OAG00956.1 - 0.013 15.6 3.0 0.013 15.6 3.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 OAG00956.1 - 0.016 15.2 0.5 0.016 15.2 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OAG00956.1 - 0.017 15.2 7.4 0.57 10.2 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OAG00956.1 - 0.044 13.2 1.2 3.5 7.2 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF1272 PF06906.11 OAG00956.1 - 0.11 12.6 10.6 0.27 11.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) PhnA_Zn_Ribbon PF08274.12 OAG00956.1 - 0.24 11.4 0.2 0.24 11.4 0.2 3.1 2 1 1 3 3 3 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 OAG00956.1 - 0.29 11.3 8.7 0.83 9.8 1.4 2.9 2 1 0 2 2 2 0 Zinc ribbon domain Baculo_RING PF05883.11 OAG00956.1 - 0.73 9.8 2.7 2.1 8.4 0.3 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.6 OAG00956.1 - 0.75 10.0 15.1 2.8 8.1 6.5 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 OAG00956.1 - 0.98 9.4 12.9 0.52 10.3 0.3 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 OAG00956.1 - 0.99 9.4 11.3 0.34 10.9 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-RING_4 PF14570.6 OAG00956.1 - 1.3 8.8 15.8 2.6 7.9 5.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAG00956.1 - 1.6 8.4 17.1 0.44 10.2 7.9 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAG00956.1 - 2.7 8.3 13.3 1.1 9.5 7.9 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 OAG00956.1 - 2.7 8.2 18.0 0.88 9.7 11.0 2.3 2 0 0 2 2 2 0 RING-variant domain PHD PF00628.29 OAG00956.1 - 4.8 7.1 19.2 1.7 8.6 8.7 2.7 2 1 1 3 3 3 0 PHD-finger Fis1_TPR_C PF14853.6 OAG00958.1 - 3.7e-26 90.9 1.9 5.9e-26 90.3 1.9 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAG00958.1 - 6.5e-19 67.3 0.2 1.2e-18 66.5 0.2 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 OAG00958.1 - 0.0005 20.0 4.4 0.0011 18.9 4.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG00958.1 - 0.091 13.4 0.4 0.21 12.3 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG00958.1 - 0.28 11.1 4.9 0.59 10.1 4.9 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.11 OAG00959.1 - 2e-35 121.2 0.0 1.9e-33 114.9 0.0 2.1 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.9 OAG00959.1 - 0.054 13.5 1.3 0.082 12.9 1.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4337 PF14235.6 OAG00959.1 - 0.16 12.1 0.4 0.24 11.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF5584 PF17822.1 OAG00960.1 - 0.072 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5584) PLDc_2 PF13091.6 OAG00962.1 - 8e-17 61.4 0.0 1.5e-05 24.9 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAG00962.1 - 2.5e-15 55.9 2.9 9.8e-09 35.0 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif MutL_C PF08676.11 OAG00964.1 - 6.1e-23 81.2 0.0 1.4e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OAG00964.1 - 8.8e-20 70.6 0.0 5.8e-19 67.9 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG00964.1 - 7.9e-11 41.9 0.1 2.1e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG00964.1 - 4.3e-08 33.6 0.1 1.1e-07 32.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HU-DNA_bdg PF14848.6 OAG00964.1 - 0.12 12.3 0.5 0.33 11.0 0.5 1.7 1 0 0 1 1 1 0 DNA-binding domain TraF PF13728.6 OAG00964.1 - 0.51 10.1 4.5 1.1 9.0 4.5 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Mitofilin PF09731.9 OAG00964.1 - 7.7 5.2 17.6 13 4.5 17.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Methyltransf_25 PF13649.6 OAG00965.1 - 4.4e-06 27.3 0.0 1.2e-05 26.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG00965.1 - 4.8e-06 26.5 0.0 9.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG00965.1 - 2.5e-05 23.9 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG00965.1 - 7e-05 22.4 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.12 OAG00965.1 - 0.00036 19.7 0.0 0.00051 19.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.12 OAG00965.1 - 0.00039 21.1 0.0 0.00094 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG00965.1 - 0.00092 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 OAG00965.1 - 0.0011 19.5 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG00965.1 - 0.0014 18.5 0.0 0.0032 17.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG00965.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG00965.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Zn_clus PF00172.18 OAG00968.1 - 1.2e-08 34.9 11.1 1.2e-08 34.9 11.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG00968.1 - 0.03 13.1 1.1 0.056 12.3 0.2 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain CLASP_N PF12348.8 OAG00969.1 - 1.8e-121 403.9 3.4 3.2e-85 285.3 0.0 2.7 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 OAG00969.1 - 0.00012 22.0 4.1 3.5 8.1 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 OAG00969.1 - 0.018 15.1 3.8 0.51 10.4 0.1 3.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG00969.1 - 0.64 10.5 10.6 0.4 11.1 0.7 5.1 7 1 1 8 8 8 0 HEAT repeats Thi4 PF01946.17 OAG00970.1 - 2.4e-114 380.4 0.0 2.9e-114 380.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG00970.1 - 6.2e-09 35.9 1.0 2.2e-08 34.1 0.8 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG00970.1 - 6.7e-06 26.2 0.2 1.8e-05 24.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG00970.1 - 2.8e-05 23.4 0.8 6.2e-05 22.2 0.4 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG00970.1 - 0.00014 21.2 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG00970.1 - 0.00028 20.9 1.1 0.00047 20.2 0.0 1.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG00970.1 - 0.00032 19.9 1.0 0.0033 16.6 0.7 2.3 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG00970.1 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG00970.1 - 0.083 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 OAG00970.1 - 0.086 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAG00970.1 - 0.14 10.9 0.5 0.21 10.3 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Acetyltransf_1 PF00583.25 OAG00971.1 - 3.5e-07 30.5 0.0 4.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG00971.1 - 2.8e-05 24.0 0.0 6.6e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG00971.1 - 6.3e-05 23.0 0.1 0.00029 20.9 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG00971.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG00971.1 - 0.00011 22.5 0.1 0.0002 21.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAG00971.1 - 0.00017 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_3 PF13302.7 OAG00971.1 - 0.039 14.6 0.2 0.095 13.4 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OAG00971.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 OAG00971.1 - 0.12 12.5 0.1 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Peptidase_S8 PF00082.22 OAG00972.1 - 9.7e-30 103.8 12.2 2.6e-29 102.4 12.2 1.5 1 1 0 1 1 1 1 Subtilase family RhoGAP PF00620.27 OAG00973.1 - 2.1e-48 164.0 1.5 6.7e-48 162.4 0.0 2.6 3 1 1 4 4 4 1 RhoGAP domain LIM PF00412.22 OAG00973.1 - 9e-14 51.5 18.5 1.9e-09 37.6 1.7 2.4 2 0 0 2 2 2 2 LIM domain DUF4119 PF13494.6 OAG00973.1 - 0.098 12.8 0.2 0.26 11.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Desulfoferrod_N PF06397.12 OAG00973.1 - 0.37 10.4 12.3 9.4 6.0 1.9 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF2757 PF10955.8 OAG00973.1 - 1.1 9.5 7.7 5.4 7.4 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) ZapB PF06005.12 OAG00973.1 - 1.9 9.0 18.7 1.7 9.2 5.1 3.0 2 0 0 2 2 2 0 Cell division protein ZapB zf-ribbon_3 PF13248.6 OAG00973.1 - 4.2 6.9 19.4 0.8 9.2 0.0 4.5 5 1 0 5 5 5 0 zinc-ribbon domain DUF4140 PF13600.6 OAG00973.1 - 4.8 7.7 5.7 3.6 8.1 0.8 3.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Zn-ribbon_8 PF09723.10 OAG00973.1 - 7.5 6.8 20.0 1.1 9.4 1.2 4.1 3 1 1 4 4 4 0 Zinc ribbon domain CHCH PF06747.13 OAG00974.1 - 2.5e-06 27.5 4.3 4.7e-06 26.6 4.3 1.5 1 0 0 1 1 1 1 CHCH domain PepSY_TM PF03929.16 OAG00974.1 - 0.024 14.3 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 PepSY-associated TM region PARG_cat PF05028.14 OAG00975.1 - 3e-40 138.6 0.0 4.1e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Bee_toxin PF17454.2 OAG00975.1 - 0.22 11.6 0.3 0.47 10.5 0.3 1.5 1 0 0 1 1 1 0 Honey bee toxin RabGAP-TBC PF00566.18 OAG00978.1 - 6.6e-19 68.4 0.0 4.7e-18 65.6 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 OAG00979.1 - 9.8e-51 172.9 0.0 1.4e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term adh_short PF00106.25 OAG00980.1 - 1e-11 44.6 0.1 3.5e-05 23.4 0.1 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00980.1 - 1.4e-05 24.8 0.0 0.04 13.5 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00980.1 - 0.0078 16.1 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 OAG00982.1 - 1.4e-34 119.6 25.7 3.7e-34 118.2 26.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 OAG00984.1 - 1.2e-16 60.6 35.2 2.2e-09 36.7 21.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAG00984.1 - 5e-16 58.9 5.4 1.5e-15 57.4 5.4 1.8 1 0 0 1 1 1 1 Nodulin-like DUF4179 PF13786.6 OAG00984.1 - 0.47 10.9 2.5 3.9 8.0 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CcmD PF04995.14 OAG00984.1 - 1.9 8.7 0.0 1.9 8.7 0.0 3.3 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Serinc PF03348.15 OAG00985.1 - 4e-160 533.5 10.1 4.5e-160 533.3 10.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ADH_zinc_N PF00107.26 OAG00986.1 - 4.2e-17 62.3 0.4 7e-17 61.6 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG00986.1 - 2.9e-09 38.1 0.0 5.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG00986.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_28 PF00295.17 OAG00988.1 - 5.1e-100 334.7 20.9 6e-100 334.4 20.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 FAD_binding_2 PF00890.24 OAG00989.1 - 1.8e-42 145.9 1.4 1.3e-41 143.1 1.4 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG00989.1 - 1.5e-10 41.2 0.8 1.5e-10 41.2 0.8 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG00989.1 - 1.7e-08 34.3 0.1 4.3e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG00989.1 - 1e-06 28.2 0.4 0.00035 19.9 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG00989.1 - 2e-06 26.8 0.7 0.00019 20.3 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 OAG00989.1 - 0.00016 22.2 0.3 0.82 10.3 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG00989.1 - 0.0002 20.5 1.3 0.00042 19.5 0.3 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAG00989.1 - 0.0046 16.2 0.1 0.0076 15.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG00989.1 - 0.0057 16.9 0.8 0.029 14.6 0.7 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG00989.1 - 0.0064 15.8 0.1 0.015 14.6 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG00989.1 - 0.019 14.3 0.2 0.036 13.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAG00989.1 - 0.038 13.2 2.2 0.074 12.3 0.2 2.3 3 0 0 3 3 3 0 Thi4 family NAD_binding_7 PF13241.6 OAG00989.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ATP-synt_G PF04718.15 OAG00989.1 - 0.081 13.8 0.0 0.32 11.8 0.0 1.9 1 1 0 1 1 1 0 Mitochondrial ATP synthase g subunit Lycopene_cycl PF05834.12 OAG00989.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.25 OAG00990.1 - 6.2e-32 110.6 1.1 1.9e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG00990.1 - 7e-29 101.0 0.0 3.2e-17 62.9 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG00990.1 - 2.5e-08 34.0 0.1 2.5e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG00990.1 - 0.0002 20.9 0.0 0.11 12.0 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG00990.1 - 0.0069 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG00990.1 - 0.035 13.2 0.1 0.059 12.5 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG00990.1 - 0.047 13.8 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OAG00990.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding TPR_10 PF13374.6 OAG00991.1 - 5.8e-70 229.5 6.2 9.2e-14 50.8 0.0 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 OAG00991.1 - 3.9e-53 177.7 8.8 4.3e-15 55.8 0.0 5.4 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG00991.1 - 1.8e-20 71.4 2.0 0.00026 20.8 0.0 6.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG00991.1 - 1.7e-13 49.5 11.4 0.043 14.0 0.0 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG00991.1 - 5.8e-13 48.1 3.1 0.19 11.6 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 OAG00991.1 - 2.6e-11 43.0 1.7 0.93 10.3 0.0 6.7 6 0 0 6 6 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG00991.1 - 1.4e-08 34.2 0.6 6.8e-08 32.0 0.1 2.4 2 1 0 2 2 2 1 NB-ARC domain TPR_16 PF13432.6 OAG00991.1 - 1.7e-08 34.9 0.0 1.7 9.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat HET PF06985.11 OAG00991.1 - 2.2e-08 34.6 10.2 2.4e-07 31.2 0.2 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TPR_19 PF14559.6 OAG00991.1 - 8.4e-08 32.6 0.1 9.6 6.8 0.0 5.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG00991.1 - 1e-07 31.6 0.1 2.3 8.6 0.0 6.6 6 0 0 6 6 5 1 Tetratricopeptide repeat NACHT PF05729.12 OAG00991.1 - 0.00044 20.2 0.3 0.0013 18.6 0.3 1.8 1 1 0 1 1 1 1 NACHT domain TPR_17 PF13431.6 OAG00991.1 - 0.001 19.3 10.2 2.5 8.7 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG00991.1 - 0.0018 18.9 7.6 1.1e+02 4.0 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.20 OAG00991.1 - 0.0044 17.2 1.7 13 6.3 0.1 5.0 5 0 0 5 5 4 0 PPR repeat DivIC PF04977.15 OAG00991.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Septum formation initiator AAA_16 PF13191.6 OAG00991.1 - 0.18 12.2 4.9 4 7.8 4.7 3.1 1 1 0 1 1 1 0 AAA ATPase domain N1221 PF07923.13 OAG00991.1 - 0.18 10.9 4.9 17 4.5 0.2 4.2 2 1 2 4 4 4 0 N1221-like protein TPR_6 PF13174.6 OAG00991.1 - 4.1 8.3 6.4 2.8e+02 2.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG00992.1 - 4.2e-115 373.0 26.7 3.4e-15 55.4 0.1 12.3 9 3 2 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 OAG00992.1 - 1.1e-83 275.6 17.5 7.7e-17 61.4 0.1 10.1 1 1 9 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 OAG00992.1 - 4.6e-40 132.7 13.3 0.00044 20.1 0.0 10.2 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_17 PF13431.6 OAG00992.1 - 8.2e-23 79.1 9.9 0.18 12.3 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 OAG00992.1 - 1.9e-22 78.0 11.9 0.23 11.3 0.0 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAG00992.1 - 3.2e-21 73.7 10.9 0.13 12.4 0.1 9.8 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG00992.1 - 7e-20 71.3 0.8 0.19 12.2 0.0 9.2 3 2 5 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG00992.1 - 9.2e-17 61.4 0.0 1.2 9.8 0.0 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG00992.1 - 9e-15 53.7 0.1 0.69 10.7 0.0 8.9 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG00992.1 - 2.7e-10 40.2 16.6 7.8e-05 22.2 2.4 3.9 1 1 3 4 4 4 3 MalT-like TPR region TPR_8 PF13181.6 OAG00992.1 - 1.5e-09 37.3 13.7 23 5.6 0.0 9.4 9 0 0 9 9 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG00992.1 - 3.5e-08 33.6 1.8 2.6 8.3 0.1 7.4 2 2 4 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 OAG00992.1 - 1.8e-07 30.9 5.9 16 6.1 0.1 8.6 9 0 0 9 9 9 0 PPR repeat AAA_16 PF13191.6 OAG00992.1 - 1e-06 29.3 0.0 2.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_20 PF14561.6 OAG00992.1 - 1.4e-05 25.3 3.3 2.7 8.4 0.0 6.4 1 1 6 7 7 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 OAG00992.1 - 2.3e-05 24.2 0.0 0.93 9.6 0.0 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAG00992.1 - 0.00011 21.5 1.7 0.00053 19.3 0.0 2.8 2 1 0 3 3 3 1 NB-ARC domain TPR_14 PF13428.6 OAG00992.1 - 0.00095 19.8 12.9 63 4.8 0.1 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat CutA1 PF03091.15 OAG00992.1 - 0.0013 18.5 26.6 7 6.6 0.1 8.3 2 1 6 9 9 8 0 CutA1 divalent ion tolerance protein DUF3157 PF11355.8 OAG00992.1 - 0.011 15.3 10.8 0.053 13.1 0.7 4.1 1 1 3 5 5 5 0 Protein of unknown function (DUF3157) ATPase_2 PF01637.18 OAG00992.1 - 0.041 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TRSP PF12500.8 OAG00992.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 IstB_IS21 PF01695.17 OAG00992.1 - 0.064 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein STD1 PF17235.2 OAG00992.1 - 0.067 12.8 0.3 0.26 10.9 0.0 2.2 2 1 0 2 2 2 0 STD1/MTH1 cwf21 PF08312.12 OAG00992.1 - 0.92 9.7 35.0 0.94 9.7 3.4 5.8 2 1 4 6 6 5 0 cwf21 domain RPN6_N PF18055.1 OAG00992.1 - 1.1 9.7 11.9 31 4.9 0.2 5.0 1 1 4 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4119 PF13494.6 OAG00992.1 - 7.6 6.7 11.6 1.2e+02 2.9 0.1 5.5 2 1 5 7 7 7 0 Domain of unknown function, B. Theta Gene description (DUF4119) Pyr_redox_2 PF07992.14 OAG00993.1 - 4.1e-43 147.7 0.2 6.2e-43 147.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAG00993.1 - 7.2e-22 77.6 0.0 1.4e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske PF00355.26 OAG00993.1 - 3e-16 59.1 0.3 1.4e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OAG00993.1 - 1.6e-15 56.9 0.0 8.2e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.27 OAG00993.1 - 8.1e-15 55.2 7.8 5.3e-14 52.5 1.2 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 OAG00993.1 - 1.5e-13 50.8 8.4 4.1e-11 43.1 5.4 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 OAG00993.1 - 5.2e-08 32.6 0.0 1.7e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 OAG00993.1 - 3e-05 23.8 0.1 0.11 12.4 0.0 3.5 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 OAG00993.1 - 0.0017 18.4 0.1 3 7.8 0.0 3.2 2 1 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG00993.1 - 0.062 12.0 0.0 7 5.2 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein Tsp45I PF06300.12 OAG00993.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme GIDA PF01134.22 OAG00993.1 - 0.1 11.7 0.5 4.5 6.3 0.2 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A Mo-co_dimer PF03404.16 OAG00994.1 - 4.5e-60 201.7 0.2 7.3e-60 201.0 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 OAG00994.1 - 4.2e-55 186.0 0.0 7.3e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 OAG00994.1 - 7.1e-35 119.3 0.0 1.3e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG00994.1 - 2e-26 92.8 0.0 4.6e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAG00994.1 - 4.4e-20 71.6 0.0 9.5e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAG00994.1 - 0.019 15.1 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain ResIII PF04851.15 OAG00996.1 - 7e-25 88.0 0.0 1.7e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG00996.1 - 4.4e-14 52.8 0.0 9.1e-13 48.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG00996.1 - 2.3e-12 47.1 0.0 4.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OAG00996.1 - 6.1e-05 22.8 0.0 0.00016 21.4 0.0 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 OAG00996.1 - 0.0024 17.2 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OAG00996.1 - 0.0083 15.9 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG00996.1 - 0.01 16.1 0.1 0.043 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG00996.1 - 0.041 14.2 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain SwrA PF17423.2 OAG00996.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Swarming motility protein T2SSE PF00437.20 OAG00996.1 - 0.1 11.6 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Myb_DNA-binding PF00249.31 OAG00997.1 - 0.0077 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_M28 PF04389.17 OAG00998.1 - 2.9e-28 98.9 0.1 6.8e-28 97.7 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG00998.1 - 2.9e-05 23.9 0.0 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ABC_membrane PF00664.23 OAG00999.1 - 1e-96 323.8 43.6 2.3e-49 168.5 18.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG00999.1 - 2e-66 222.7 0.0 2e-32 112.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG00999.1 - 2.9e-14 53.0 5.5 1.1e-05 25.0 0.1 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OAG00999.1 - 5.6e-08 32.0 1.3 0.00025 20.0 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAG00999.1 - 4.5e-07 29.5 0.3 0.0067 16.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG00999.1 - 6.8e-07 29.8 0.1 0.048 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG00999.1 - 7.6e-07 29.5 1.9 0.075 13.3 0.2 3.8 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAG00999.1 - 1.8e-05 24.7 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAG00999.1 - 2.9e-05 24.0 0.0 5.1 6.8 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG00999.1 - 7.9e-05 22.5 0.0 0.088 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 OAG00999.1 - 0.00013 21.3 0.0 0.79 9.0 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_25 PF13481.6 OAG00999.1 - 0.00063 19.4 0.1 1 8.9 0.1 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 OAG00999.1 - 0.0014 18.8 5.3 0.87 9.9 0.2 4.3 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 OAG00999.1 - 0.0035 16.6 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 OAG00999.1 - 0.011 15.3 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 OAG00999.1 - 0.011 16.2 0.3 5.4 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG00999.1 - 0.024 14.8 0.3 10 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAG00999.1 - 0.036 14.3 0.5 4.5 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAG00999.1 - 0.082 13.0 0.3 1.4 8.9 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_30 PF13604.6 OAG00999.1 - 0.11 12.2 6.9 5.5 6.7 0.0 4.1 4 1 0 4 4 3 0 AAA domain AAA_5 PF07728.14 OAG00999.1 - 0.13 12.3 0.0 13 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Synapsin_N PF10581.9 OAG00999.1 - 0.15 12.0 0.0 21 5.2 0.2 2.5 2 0 0 2 2 2 0 Synapsin N-terminal Fungal_trans PF04082.18 OAG01001.1 - 1.7e-17 63.4 0.1 3.1e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tmemb_cc2 PF10267.9 OAG01001.1 - 0.00034 19.9 0.5 0.00052 19.3 0.5 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein CCDC53 PF10152.9 OAG01001.1 - 0.16 12.4 0.7 0.32 11.4 0.7 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex YEATS PF03366.16 OAG01002.1 - 5e-12 45.6 0.1 7.9e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 YEATS family zf-C3HC4_3 PF13920.6 OAG01002.1 - 1.1e-05 25.2 6.5 0.00048 19.9 2.3 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG01002.1 - 1.4e-05 25.1 2.5 1.4e-05 25.1 2.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAG01002.1 - 1.8e-05 24.7 3.6 1.8e-05 24.7 3.6 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG01002.1 - 5.5e-05 22.9 8.0 5.9e-05 22.8 3.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG01002.1 - 8.3e-05 22.4 2.9 8.3e-05 22.4 2.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG01002.1 - 0.0004 20.3 7.7 0.0018 18.2 7.7 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG01002.1 - 0.0024 18.2 11.7 0.027 14.8 11.7 2.1 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAG01002.1 - 0.0047 16.8 10.3 0.29 11.0 6.3 3.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OAG01002.1 - 0.036 14.2 4.9 0.042 14.0 3.0 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 OAG01002.1 - 0.075 12.9 1.2 2.8 7.9 0.6 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 OAG01002.1 - 0.096 12.3 2.3 0.22 11.2 2.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type U-box PF04564.15 OAG01002.1 - 0.1 12.8 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 U-box domain CcmH PF03918.14 OAG01002.1 - 0.13 11.6 0.1 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Cytochrome C biogenesis protein RecR PF02132.15 OAG01002.1 - 0.56 9.8 3.3 2.5 7.8 0.8 2.5 2 0 0 2 2 2 0 RecR protein DZR PF12773.7 OAG01002.1 - 1.7 8.7 5.2 15 5.7 5.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-rbx1 PF12678.7 OAG01002.1 - 2.2 8.6 10.5 2.5 8.5 4.7 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain TauD PF02668.16 OAG01003.1 - 1.9e-32 113.1 0.0 3.9e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 OAG01004.1 - 1.8e-56 191.9 2.0 2.2e-56 191.6 2.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAG01005.1 - 1.7e-19 70.0 48.6 2.8e-17 62.7 31.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 OAG01005.1 - 0.006 16.2 1.5 0.006 16.2 1.5 2.0 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 Amidohydro_2 PF04909.14 OAG01006.1 - 2.3e-26 93.2 0.1 3.1e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Adeno_E3 PF06040.11 OAG01006.1 - 0.11 12.7 0.1 0.4 10.9 0.1 1.9 1 1 0 2 2 2 0 Adenovirus E3 protein ABC_tran PF00005.27 OAG01007.1 - 7e-48 162.6 0.1 7.4e-24 84.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 OAG01007.1 - 4.6e-26 90.7 0.0 1.3e-25 89.2 0.0 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 OAG01007.1 - 2.6e-16 60.3 0.0 0.0021 17.9 0.0 5.0 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG01007.1 - 6e-16 58.5 0.0 3.1e-06 26.8 0.0 3.7 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG01007.1 - 1.1e-10 42.4 0.2 0.00023 21.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG01007.1 - 8e-08 31.9 0.1 0.017 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG01007.1 - 1.8e-07 31.5 0.0 0.0028 17.9 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.6 OAG01007.1 - 3.5e-07 30.6 0.1 0.045 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAG01007.1 - 8.4e-07 29.0 0.2 0.001 19.0 0.0 2.8 3 0 0 3 3 2 1 RsgA GTPase PduV-EutP PF10662.9 OAG01007.1 - 2.4e-06 27.3 0.1 0.12 12.1 0.0 3.2 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OAG01007.1 - 5.1e-06 27.0 0.0 0.14 12.6 0.1 4.3 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAG01007.1 - 7e-06 26.1 0.0 0.0059 16.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG01007.1 - 1.1e-05 25.9 0.2 0.31 11.4 0.0 3.8 5 0 0 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 OAG01007.1 - 2e-05 25.2 0.1 0.35 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 OAG01007.1 - 0.00013 22.0 0.0 0.31 11.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAG01007.1 - 0.00014 22.2 0.0 0.8 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 OAG01007.1 - 0.00016 21.7 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 OAG01007.1 - 0.00016 20.7 0.1 0.07 12.1 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 OAG01007.1 - 0.00035 20.7 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 OAG01007.1 - 0.00037 20.7 0.4 0.21 11.6 0.0 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_15 PF13175.6 OAG01007.1 - 0.00039 20.2 1.1 1.2 8.8 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain AAA_24 PF13479.6 OAG01007.1 - 0.00046 20.0 0.0 1.3 8.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_13 PF13166.6 OAG01007.1 - 0.00053 18.8 1.6 0.45 9.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.23 OAG01007.1 - 0.00056 20.0 0.0 0.0033 17.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 OAG01007.1 - 0.00065 19.5 0.0 0.97 9.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 OAG01007.1 - 0.00081 18.6 0.4 1.2 8.2 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit NB-ARC PF00931.22 OAG01007.1 - 0.00084 18.6 0.1 0.044 13.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.19 OAG01007.1 - 0.00093 18.8 0.0 1.2 8.7 0.0 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 OAG01007.1 - 0.0018 17.9 0.1 1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OAG01007.1 - 0.0024 18.0 0.0 2 8.7 0.0 3.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit HEAT PF02985.22 OAG01007.1 - 0.0026 17.9 0.2 5.3 7.6 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat Roc PF08477.13 OAG01007.1 - 0.0043 17.3 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 OAG01007.1 - 0.0058 16.4 0.0 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 OAG01007.1 - 0.0063 16.5 0.0 0.95 9.3 0.0 2.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea TsaE PF02367.17 OAG01007.1 - 0.0084 16.1 0.2 7.1 6.6 0.1 3.4 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OAG01007.1 - 0.016 14.7 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAG01007.1 - 0.019 14.7 0.0 10 5.8 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 OAG01007.1 - 0.024 14.3 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CLP1_P PF16575.5 OAG01007.1 - 0.025 14.4 0.1 1.5 8.6 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 OAG01007.1 - 0.026 14.5 0.0 8.1 6.5 0.0 3.3 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OAG01007.1 - 0.027 14.4 0.0 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 OAG01007.1 - 0.031 13.9 0.0 9.5 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAG01007.1 - 0.033 13.6 0.0 4.7 6.5 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.18 OAG01007.1 - 0.043 13.1 0.0 4.4 6.5 0.0 2.7 2 0 0 2 2 2 0 Septin T2SSE PF00437.20 OAG01007.1 - 0.045 12.8 0.1 7.7 5.5 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein HEAT_2 PF13646.6 OAG01007.1 - 0.047 14.1 2.3 4 7.9 0.4 3.5 2 1 1 3 3 3 0 HEAT repeats ParcG PF10274.9 OAG01007.1 - 0.054 13.6 2.0 2.4 8.3 0.2 3.2 2 1 2 4 4 4 0 Parkin co-regulated protein NTPase_1 PF03266.15 OAG01007.1 - 0.072 13.0 0.0 16 5.3 0.1 2.8 3 0 0 3 3 2 0 NTPase HEAT_EZ PF13513.6 OAG01007.1 - 0.086 13.4 1.9 21 5.7 0.1 4.6 5 2 1 6 6 3 0 HEAT-like repeat MukB PF04310.12 OAG01007.1 - 0.087 12.6 0.1 13 5.5 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal Arf PF00025.21 OAG01007.1 - 0.098 12.1 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Ploopntkinase3 PF18751.1 OAG01007.1 - 0.15 12.0 0.1 26 4.7 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Alpha-L-AF_C PF06964.12 OAG01010.1 - 1.3e-28 100.2 0.0 2.2e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 OAG01010.1 - 0.045 13.7 0.7 0.09 12.7 0.2 1.8 2 0 0 2 2 2 0 Glycoside hydrolase family 44 Sugar_tr PF00083.24 OAG01011.1 - 3.4e-100 336.0 18.3 3.9e-100 335.9 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01011.1 - 6.9e-28 97.6 26.6 2.5e-23 82.6 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S8 PF00082.22 OAG01013.1 - 5.9e-21 75.0 16.0 2.7e-20 72.8 16.0 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG01013.1 - 1.6e-07 31.9 0.0 3.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Thiolase_N PF00108.23 OAG01014.1 - 2.5e-68 230.3 0.0 3.4e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG01014.1 - 2.5e-41 140.2 1.8 2.5e-41 140.2 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG01014.1 - 0.0074 16.1 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG01014.1 - 0.014 15.0 0.6 0.059 12.9 0.3 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain zf-RING_2 PF13639.6 OAG01015.1 - 0.0008 19.7 0.3 0.0008 19.7 0.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OAG01015.1 - 0.028 14.2 0.3 0.061 13.1 0.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG01015.1 - 0.042 13.7 0.4 0.042 13.7 0.4 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG01015.1 - 0.069 13.4 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG01015.1 - 0.38 10.7 2.6 0.32 10.9 0.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AlaDh_PNT_N PF05222.15 OAG01018.1 - 3.8e-29 101.7 0.0 5.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 OAG01018.1 - 0.0019 17.5 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sulfate_transp PF00916.20 OAG01019.1 - 3.8e-82 276.1 11.9 5.1e-82 275.6 11.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG01019.1 - 8.4e-16 57.7 0.0 1.7e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OAG01019.1 - 0.0045 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 STAS domain KTI12 PF08433.10 OAG01019.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MFS_MOT1 PF16983.5 OAG01019.1 - 0.51 10.8 12.3 0.11 12.9 3.6 2.6 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Sugar_tr PF00083.24 OAG01020.1 - 2.5e-36 125.5 21.5 3.7e-35 121.7 21.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01020.1 - 1.2e-31 110.0 38.3 7e-29 100.9 21.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG01020.1 - 0.73 8.2 7.7 0.091 11.2 0.7 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_7 PF00840.20 OAG01021.1 - 3.9e-135 450.9 12.9 4.8e-135 450.6 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 LPD7 PF18821.1 OAG01022.1 - 0.021 14.9 0.1 0.048 13.8 0.1 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 DUF4419 PF14388.6 OAG01023.1 - 2.2e-102 342.5 0.0 2.8e-102 342.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Fungal_trans PF04082.18 OAG01024.1 - 6.5e-20 71.3 0.2 9e-20 70.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01024.1 - 3.6e-07 30.2 9.1 7.1e-07 29.3 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 OAG01025.1 - 1.9e-14 54.2 0.0 6.6e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG01025.1 - 0.0014 18.6 0.0 0.0039 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG01025.1 - 0.057 13.8 0.2 0.057 13.8 0.2 2.6 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 OAG01025.1 - 0.081 13.2 3.8 0.13 12.5 0.1 2.8 2 1 1 3 3 3 0 AAA domain RuvB_N PF05496.12 OAG01025.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DSPc PF00782.20 OAG01026.1 - 4.6e-09 36.2 0.0 8.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG01026.1 - 0.00055 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG01026.1 - 0.0056 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OAG01026.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 OAG01026.1 - 0.036 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTEN_C2 PF10409.9 OAG01026.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein RhgB_N PF09284.10 OAG01027.1 - 6.2e-100 333.9 0.7 8.7e-100 333.4 0.7 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 OAG01027.1 - 3.5e-34 118.1 0.1 9e-34 116.7 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 OAG01027.1 - 6.4e-20 70.7 3.7 3.2e-19 68.5 1.5 3.1 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OAG01027.1 - 7.8e-06 26.1 1.6 4.2e-05 23.7 0.6 2.7 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain PEGA PF08308.11 OAG01027.1 - 0.0015 18.4 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 PEGA domain DUF3823 PF12866.7 OAG01027.1 - 0.11 12.8 0.1 0.31 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain PhzC-PhzF PF02567.16 OAG01028.1 - 1.1e-40 139.9 0.1 1.3e-40 139.7 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF2316 PF10078.9 OAG01029.1 - 0.17 12.1 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF3328 PF11807.8 OAG01030.1 - 4.8e-49 167.1 0.7 5.7e-49 166.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DAO PF01266.24 OAG01031.1 - 6.3e-59 200.3 0.1 7.8e-59 200.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG01031.1 - 0.00012 22.2 0.8 0.00026 21.2 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG01031.1 - 0.015 14.5 0.3 0.13 11.5 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG01031.1 - 0.081 12.2 0.6 0.15 11.3 0.3 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG01031.1 - 0.17 11.1 0.9 0.58 9.4 0.5 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG01031.1 - 0.19 10.7 0.2 1.2 8.1 0.4 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OAG01031.1 - 0.25 10.6 3.2 0.36 10.1 1.9 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lentiviral_Tat PF02998.14 OAG01032.1 - 0.27 11.3 4.7 0.7 10.0 4.7 1.7 1 0 0 1 1 1 0 Lentiviral Tat protein Chitin_synth_2 PF03142.15 OAG01034.1 - 2.2e-23 82.7 2.2 2.2e-23 82.7 2.2 3.0 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG01034.1 - 4.2e-14 52.9 1.9 4.2e-14 52.9 1.9 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG01034.1 - 2.7e-07 30.7 0.0 7.3e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG01034.1 - 0.035 13.9 0.0 5.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 MIF4G PF02854.19 OAG01037.1 - 2.4e-62 210.3 0.4 3.1e-31 108.7 0.0 3.7 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 OAG01037.1 - 1.5e-39 135.9 8.3 1.5e-39 135.9 8.3 3.8 4 0 0 4 4 4 1 Up-frameshift suppressor 2 Ank_2 PF12796.7 OAG01039.1 - 1.1e-21 77.2 0.5 1.5e-07 31.9 0.0 4.9 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG01039.1 - 1.7e-15 55.5 0.3 0.77 10.5 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OAG01039.1 - 1.3e-12 48.0 0.7 0.00023 21.6 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG01039.1 - 2.7e-10 40.3 0.6 0.01 16.1 0.0 5.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG01039.1 - 3.2e-09 36.8 0.1 4.5 7.9 0.1 6.7 5 1 0 5 5 5 3 Ankyrin repeat Meth_synt_2 PF01717.18 OAG01040.1 - 3e-14 53.0 0.0 7.4e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG01040.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain adh_short PF00106.25 OAG01041.1 - 2.7e-21 75.9 0.0 3.2e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01041.1 - 5e-12 45.9 0.0 6.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG01041.1 - 0.0021 17.5 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG01041.1 - 0.014 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 KR domain Tachystatin_B PF11478.8 OAG01042.1 - 0.13 12.2 0.7 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B DIM PF08194.12 OAG01042.1 - 0.16 12.2 0.7 0.56 10.5 0.7 1.9 1 0 0 1 1 1 0 DIM protein PLA2_B PF01735.18 OAG01043.1 - 2.4e-24 85.6 0.0 3.8e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.20 OAG01044.1 - 5.1e-07 29.6 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 OAG01044.1 - 0.014 15.7 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Sec5 PF15469.6 OAG01045.1 - 2.3e-38 131.9 0.0 1.2e-37 129.6 0.0 2.2 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 OAG01045.1 - 0.00033 20.7 0.0 0.0016 18.5 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Sec15 PF04091.12 OAG01045.1 - 0.0074 15.7 0.0 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Exo70 PF03081.15 OAG01046.1 - 8.3e-88 295.0 0.0 2.6e-87 293.3 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DASH_Dam1 PF08653.10 OAG01046.1 - 0.026 14.3 1.4 8.5 6.3 0.0 4.7 5 0 0 5 5 4 0 DASH complex subunit Dam1 MnmE_helical PF12631.7 OAG01046.1 - 0.029 14.5 2.9 3.6 7.7 2.9 3.1 2 1 0 3 3 3 0 MnmE helical domain FUSC PF04632.12 OAG01046.1 - 0.034 12.7 5.1 1.1 7.7 2.3 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Pec_lyase PF09492.10 OAG01046.1 - 0.061 12.7 0.1 0.37 10.1 0.1 2.0 1 1 1 2 2 2 0 Pectic acid lyase Spectrin PF00435.21 OAG01046.1 - 0.15 12.5 1.2 19 5.8 0.0 3.4 3 0 0 3 3 3 0 Spectrin repeat DUF4041 PF13250.6 OAG01046.1 - 0.45 10.4 2.6 1.5 8.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) HBM PF16591.5 OAG01046.1 - 0.94 8.9 8.5 1.3 8.4 6.3 2.3 2 1 0 2 2 2 0 Helical bimodular sensor domain Sec34 PF04136.15 OAG01046.1 - 0.97 9.3 5.6 1.8 8.5 0.2 3.3 4 0 0 4 4 4 0 Sec34-like family NEMO PF11577.8 OAG01046.1 - 1 9.4 6.1 0.21 11.7 0.7 2.7 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO TACC_C PF05010.14 OAG01046.1 - 1.2 8.9 7.2 1.6 8.5 0.2 3.2 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ABC_tran_CTD PF16326.5 OAG01046.1 - 1.4 9.2 4.4 23 5.3 1.3 4.0 3 1 0 3 3 2 0 ABC transporter C-terminal domain GAS PF13851.6 OAG01046.1 - 2 7.7 14.0 3.3 7.0 4.9 3.2 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding FliJ PF02050.16 OAG01046.1 - 4 7.7 8.1 0.95 9.7 0.1 3.4 3 1 1 4 4 4 0 Flagellar FliJ protein BAR_3 PF16746.5 OAG01046.1 - 9.3 5.9 8.8 11 5.6 3.1 3.4 3 1 0 3 3 3 0 BAR domain of APPL family Septin PF00735.18 OAG01047.1 - 8.5e-121 402.5 0.7 8.5e-121 402.5 0.7 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAG01047.1 - 2.4e-08 34.1 0.1 2.4e-08 34.1 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG01047.1 - 8e-05 22.3 4.1 0.0012 18.4 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG01047.1 - 0.0003 20.7 10.7 0.00071 19.5 0.4 3.6 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 OAG01047.1 - 0.00035 20.0 0.0 0.00035 20.0 0.0 2.5 2 2 1 3 3 3 1 AIG1 family Roc PF08477.13 OAG01047.1 - 0.0017 18.6 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OAG01047.1 - 0.0018 18.7 0.8 0.0048 17.3 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 OAG01047.1 - 0.0025 17.5 0.9 0.01 15.4 0.0 2.4 3 0 0 3 3 3 1 Ras family RNA_helicase PF00910.22 OAG01047.1 - 0.0031 17.9 1.1 0.48 10.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 OAG01047.1 - 0.0071 16.6 1.3 0.028 14.7 0.1 2.6 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 OAG01047.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OAG01047.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG01047.1 - 0.016 15.7 0.3 0.016 15.7 0.3 2.7 1 1 1 3 3 3 0 ABC transporter Piezo_RRas_bdg PF12166.8 OAG01047.1 - 0.022 14.1 3.5 0.034 13.5 3.5 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain FtsK_SpoIIIE PF01580.18 OAG01047.1 - 0.042 13.2 0.0 0.099 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 OAG01047.1 - 0.042 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 OAG01047.1 - 0.053 13.2 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.23 OAG01047.1 - 0.056 13.5 10.7 0.81 9.7 0.0 4.1 4 1 0 4 4 3 0 Dynamin family Exonuc_VII_L PF02601.15 OAG01047.1 - 0.23 11.0 6.8 0.38 10.3 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 OAG01047.1 - 3.4 7.4 5.6 22 4.7 0.1 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein DUF4085 PF13315.6 OAG01047.1 - 8.5 5.9 12.0 0.25 10.9 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) AP1AR PF15745.5 OAG01047.1 - 9.4 5.8 15.3 18 4.9 14.7 1.7 1 1 0 1 1 1 0 AP-1 complex-associated regulatory protein UPF0121 PF03661.13 OAG01048.1 - 2.6e-31 108.9 3.1 3.3e-31 108.6 3.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Phosphorylase PF00343.20 OAG01051.1 - 0 1068.1 0.0 0 1067.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Yip1 PF04893.17 OAG01052.1 - 5.9e-14 52.2 13.4 1.2e-13 51.2 13.3 1.5 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 OAG01052.1 - 0.0041 16.7 6.3 0.01 15.4 5.6 2.0 1 1 0 2 2 2 1 YIF1 Glyco_hydro_3_C PF01915.22 OAG01053.1 - 2.1e-44 152.0 0.0 3.1e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG01053.1 - 5.4e-29 101.6 0.0 8.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG01053.1 - 8e-06 25.9 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain AAA PF00004.29 OAG01054.1 - 0.018 15.4 0.0 0.066 13.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG01054.1 - 0.027 14.7 0.0 5.6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain CRT-like PF08627.10 OAG01054.1 - 0.062 12.2 0.3 0.096 11.6 0.3 1.1 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like DUF4996 PF16387.5 OAG01054.1 - 0.15 12.5 0.0 0.51 10.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF1505 PF07403.11 OAG01055.1 - 0.07 13.3 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) PGAP1 PF07819.13 OAG01057.1 - 6.3e-89 297.7 0.0 1.1e-88 296.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAG01057.1 - 0.0003 21.5 0.4 0.00063 20.4 0.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAG01057.1 - 0.0047 16.5 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OAG01057.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.7 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 OAG01057.1 - 0.017 14.4 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG01057.1 - 0.024 14.3 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAG01057.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 OAG01057.1 - 0.19 11.1 0.0 0.78 9.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) zf-RING_5 PF14634.6 OAG01058.1 - 0.0037 17.2 0.7 0.0075 16.2 0.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG01058.1 - 0.022 15.1 1.2 0.039 14.3 0.5 1.8 1 1 0 1 1 1 0 Ring finger domain TilS PF09179.11 OAG01058.1 - 0.18 12.3 0.6 0.65 10.5 0.1 2.2 2 0 0 2 2 2 0 TilS substrate binding domain DUF4470 PF14737.6 OAG01059.1 - 8.4e-23 80.4 0.1 2.8e-22 78.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 OAG01059.1 - 9e-05 22.5 2.3 9e-05 22.5 2.3 1.7 2 0 0 2 2 2 1 MYND finger Peptidase_S8 PF00082.22 OAG01061.1 - 0.002 17.4 0.0 0.0023 17.3 0.0 1.0 1 0 0 1 1 1 1 Subtilase family Methyltransf_25 PF13649.6 OAG01062.1 - 8.4e-13 48.8 0.0 1.5e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG01062.1 - 1.9e-11 44.4 0.0 2.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG01062.1 - 1.3e-09 38.7 0.0 2.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG01062.1 - 5.5e-08 32.7 0.0 7.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG01062.1 - 4.6e-05 23.0 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OAG01062.1 - 7.9e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG01062.1 - 8.4e-05 22.1 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OAG01062.1 - 0.00015 21.2 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 OAG01062.1 - 0.00022 20.9 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_2 PF00891.18 OAG01062.1 - 0.00042 19.7 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 OAG01062.1 - 0.021 14.5 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF43 PF01861.16 OAG01062.1 - 0.026 13.7 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_9 PF08003.11 OAG01062.1 - 0.05 12.5 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.10 OAG01062.1 - 0.17 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Abhydrolase_6 PF12697.7 OAG01063.1 - 3e-16 60.7 0.1 3.8e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.18 OAG01064.1 - 1.7e-09 37.7 4.5 3.5e-09 36.6 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG01064.1 - 0.00061 18.7 0.2 0.00098 18.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 OAG01066.1 - 8.7e-38 130.0 3.4 1.5e-37 129.3 3.4 1.3 1 0 0 1 1 1 1 RTA1 like protein ApbA PF02558.16 OAG01067.1 - 3.9e-33 114.2 0.0 1.1e-32 112.8 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAG01067.1 - 5.3e-24 84.8 0.0 3e-23 82.4 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 OAG01067.1 - 0.001 19.3 1.5 0.0023 18.2 0.1 2.5 3 1 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 OAG01067.1 - 0.025 14.8 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG01067.1 - 0.034 13.7 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 OAG01067.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase ThiF PF00899.21 OAG01067.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 ThiF family Egh16-like PF11327.8 OAG01068.1 - 7.7e-66 222.0 13.3 9.4e-66 221.7 13.3 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Cu_amine_oxid PF01179.20 OAG01069.1 - 2.2e-160 534.1 0.0 2.8e-160 533.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAG01069.1 - 6.6e-10 39.1 0.1 1.9e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAG01069.1 - 0.0022 18.4 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain adh_short_C2 PF13561.6 OAG01072.1 - 2.9e-46 157.9 1.0 1.4e-40 139.3 0.4 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG01072.1 - 1.1e-43 149.0 0.8 1.3e-43 148.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG01072.1 - 8.9e-15 55.1 0.1 1.5e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG01072.1 - 0.00012 21.7 0.2 0.00084 18.9 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG01072.1 - 0.00025 20.3 0.1 0.00037 19.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ribosomal_L26 PF16906.5 OAG01072.1 - 0.068 13.6 0.0 0.26 11.8 0.0 1.8 1 1 1 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal F420_oxidored PF03807.17 OAG01072.1 - 0.093 13.3 0.2 0.18 12.4 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 OAG01072.1 - 0.11 11.5 0.4 0.36 9.9 0.4 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain p450 PF00067.22 OAG01073.1 - 9e-30 103.8 0.0 1.4e-16 60.3 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 ESCRT-II PF05871.12 OAG01073.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 ESCRT-II complex subunit DUF3042 PF11240.8 OAG01073.1 - 0.18 11.8 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) TrkH PF02386.16 OAG01076.1 - 8.2e-77 258.7 4.2 8.2e-77 258.7 4.2 2.1 2 0 0 2 2 2 2 Cation transport protein DUF2182 PF09948.9 OAG01076.1 - 0.012 15.6 1.7 0.012 15.6 1.7 2.1 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) TPP_enzyme_N PF02776.18 OAG01078.1 - 3.4e-37 127.7 0.0 5.9e-36 123.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG01078.1 - 6.2e-19 68.3 0.0 1.2e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG01078.1 - 1.1e-10 41.4 0.0 2.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain SET PF00856.28 OAG01079.1 - 8e-14 52.4 0.1 3.8e-13 50.2 0.0 2.1 2 1 0 2 2 2 1 SET domain PID_2 PF14719.6 OAG01079.1 - 0.09 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) EcKinase PF02958.20 OAG01080.1 - 2.1e-13 50.3 0.0 4e-13 49.3 0.0 1.3 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 OAG01080.1 - 6.1e-08 32.9 0.1 5.8e-07 29.7 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG01080.1 - 0.0058 16.2 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase TPR_10 PF13374.6 OAG01082.1 - 2.5e-17 62.1 1.8 1.1e-10 41.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG01082.1 - 4.8e-13 49.2 0.0 1.7e-06 28.2 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.12 OAG01082.1 - 8.1e-08 32.4 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 OAG01082.1 - 9.1e-07 28.3 0.0 0.034 13.3 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain DUF2845 PF11006.8 OAG01082.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) AAA_16 PF13191.6 OAG01082.1 - 0.22 11.9 3.4 0.53 10.6 0.7 2.8 2 1 0 2 2 2 0 AAA ATPase domain FixQ PF05545.11 OAG01083.1 - 1.7 8.7 3.8 3.1 7.8 3.8 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SAP130_C PF16014.5 OAG01083.1 - 7.8 5.5 15.6 17 4.4 15.6 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Cytochrome_CBB3 PF13442.6 OAG01084.1 - 0.0042 17.4 0.2 0.012 15.9 0.2 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III GFA PF04828.14 OAG01084.1 - 1.5 9.2 9.2 0.055 13.8 2.4 2.2 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Abhydrolase_6 PF12697.7 OAG01085.1 - 1e-13 52.4 0.7 1e-13 52.4 0.7 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG01085.1 - 1.2e-12 48.1 0.1 2.5e-11 43.7 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG01085.1 - 1.5e-12 47.3 0.0 4.4e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG01085.1 - 1.4e-05 25.1 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG01085.1 - 0.0024 17.4 0.1 0.044 13.3 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAG01085.1 - 0.0051 16.6 0.0 0.24 11.2 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 OAG01085.1 - 0.074 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 OAG01085.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 OAG01085.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Ser_hydrolase PF06821.13 OAG01085.1 - 0.13 12.2 0.0 0.44 10.4 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase Lipase_3 PF01764.25 OAG01085.1 - 0.13 12.2 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.13 OAG01085.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) MFS_1 PF07690.16 OAG01087.1 - 5.3e-51 173.6 36.7 5.3e-51 173.6 36.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG01087.1 - 6.4e-15 55.0 14.6 6.4e-15 55.0 14.6 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG01087.1 - 4e-09 35.5 3.8 9.3e-09 34.2 3.8 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UCR_TM PF02921.14 OAG01087.1 - 0.075 13.5 0.4 0.35 11.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Zn_clus PF00172.18 OAG01088.1 - 7.5e-09 35.6 8.4 1.7e-08 34.5 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG01088.1 - 2.2e-07 30.2 0.1 3.9e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.23 OAG01089.1 - 4.7e-63 213.0 0.9 1e-62 211.9 0.1 1.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG01089.1 - 1.2e-20 73.8 0.0 3.8e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Acetyltransf_1 PF00583.25 OAG01089.1 - 2.7e-14 53.4 0.0 6.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG01089.1 - 3.4e-10 39.9 0.0 8.8e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG01089.1 - 6.8e-10 39.2 0.0 1.5e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ResIII PF04851.15 OAG01089.1 - 1.5e-08 34.8 1.0 4e-08 33.4 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit FR47 PF08445.10 OAG01089.1 - 1.2e-06 28.3 0.0 3.5e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein HDA2-3 PF11496.8 OAG01089.1 - 0.00013 21.2 0.0 0.006 15.8 0.0 2.5 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Acetyltransf_CG PF14542.6 OAG01089.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase AT_hook PF02178.19 OAG01089.1 - 0.0097 15.7 13.9 0.46 10.5 2.6 2.9 2 0 0 2 2 2 2 AT hook motif Acetyltransf_4 PF13420.7 OAG01089.1 - 0.028 14.6 0.0 0.53 10.4 0.0 3.0 4 0 0 4 4 3 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG01089.1 - 0.097 12.7 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3328 PF11807.8 OAG01091.1 - 1.6e-19 70.6 9.5 1.5e-18 67.4 9.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PBP1_TM PF14812.6 OAG01091.1 - 0.0017 18.7 1.7 0.0033 17.8 1.7 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_C37 PF05416.12 OAG01091.1 - 1.1 7.7 3.1 2.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Southampton virus-type processing peptidase adh_short PF00106.25 OAG01092.1 - 3.5e-48 163.7 1.0 4.5e-48 163.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01092.1 - 2.7e-43 148.2 0.8 8.8e-43 146.5 0.8 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG01092.1 - 0.00016 21.3 0.0 0.00026 20.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG01092.1 - 0.00057 19.9 0.8 0.0039 17.1 0.8 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG01092.1 - 0.0092 15.7 0.2 0.05 13.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.26 OAG01092.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DFP PF04127.15 OAG01092.1 - 0.072 12.9 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.6 OAG01093.1 - 5.6e-13 49.2 0.0 8.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG01093.1 - 1.4e-11 44.4 0.0 2.1e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 OAG01093.1 - 8.9e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG01093.1 - 2.4e-05 23.9 0.0 0.00031 20.3 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAG01093.1 - 3e-05 23.6 0.1 0.00022 20.8 0.3 2.3 3 1 0 3 3 3 1 short chain dehydrogenase TrkA_N PF02254.18 OAG01093.1 - 0.034 14.4 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 OAG01093.1 - 0.037 13.2 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG01093.1 - 0.11 11.4 0.0 0.28 10.2 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lactamase_B PF00753.27 OAG01094.1 - 9.7e-06 25.7 4.2 8.7e-05 22.6 4.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OAG01094.1 - 0.055 13.4 0.6 0.41 10.5 0.1 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DUF2685 PF10886.8 OAG01094.1 - 0.11 12.7 0.1 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) Chitin_bind_1 PF00187.19 OAG01095.1 - 5.8e-17 61.9 80.4 2e-08 34.6 21.1 4.3 3 3 0 3 3 3 3 Chitin recognition protein Trypan_PARP PF05887.11 OAG01095.1 - 1.5 8.8 14.7 5.4 7.0 1.3 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Sugar_tr PF00083.24 OAG01096.1 - 3.8e-113 378.7 27.0 4.4e-113 378.5 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01096.1 - 1.8e-20 73.2 23.6 1.8e-20 73.2 23.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sulfatase PF00884.23 OAG01097.1 - 2.3e-66 224.3 0.1 3.4e-66 223.8 0.1 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OAG01097.1 - 1.3e-21 76.8 5.8 2.7e-12 46.9 1.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 OAG01097.1 - 2.3e-09 37.3 1.3 2e-08 34.2 1.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OAG01097.1 - 5.5e-05 23.9 0.1 0.00013 22.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 OAG01097.1 - 0.0012 17.5 0.2 0.0037 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) PsbN PF02468.15 OAG01098.1 - 0.24 11.3 0.8 0.55 10.1 0.8 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Glyco_hydro_3 PF00933.21 OAG01099.1 - 5.7e-52 177.1 0.0 7.5e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAG01099.1 - 3.2e-39 135.0 0.0 5.1e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OAG01099.1 - 4.4e-14 52.3 0.3 7.7e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain p450 PF00067.22 OAG01100.1 - 2.2e-55 188.3 0.0 2.8e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NRDE-2 PF08424.10 OAG01100.1 - 0.07 12.2 0.3 0.11 11.6 0.3 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference zf-FLZ PF04570.14 OAG01100.1 - 0.082 12.4 0.3 0.2 11.1 0.3 1.7 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 TMEM206 PF15122.6 OAG01100.1 - 0.15 11.2 1.6 11 5.0 0.1 3.0 2 1 1 3 3 3 0 TMEM206 protein family DUF4939 PF16297.5 OAG01101.1 - 0.0012 18.7 0.0 0.0014 18.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) YfcL PF08891.11 OAG01101.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 YfcL protein Rhodanese_C PF12368.8 OAG01102.1 - 4e-13 49.5 10.9 4e-13 49.5 10.9 1.6 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 OAG01102.1 - 0.048 14.2 0.1 0.15 12.6 0.1 1.8 1 1 0 1 1 1 0 Rhodanese-like domain WD40 PF00400.32 OAG01104.1 - 1.2e-15 57.5 3.3 1.4e-09 38.4 0.0 3.8 2 1 1 3 3 3 2 WD domain, G-beta repeat NACHT PF05729.12 OAG01104.1 - 9.3e-08 32.2 0.0 2.9e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 OAG01104.1 - 5.7e-07 29.1 0.8 1.5e-06 27.8 0.8 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 OAG01104.1 - 8.4e-07 29.5 0.5 1.8e-05 25.2 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 OAG01104.1 - 2.7e-05 24.4 0.0 0.00021 21.5 0.0 2.4 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 OAG01104.1 - 0.00023 21.6 0.0 0.00089 19.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SesA PF17107.5 OAG01104.1 - 0.00026 21.2 0.8 0.00026 21.2 0.8 2.0 2 0 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 OAG01104.1 - 0.00046 20.5 0.3 0.0035 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain PD40 PF07676.12 OAG01104.1 - 0.0013 18.7 0.3 34 4.5 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 OAG01104.1 - 0.0018 17.9 0.2 3.7 7.3 0.0 3.6 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature NB-ARC PF00931.22 OAG01104.1 - 0.0029 16.8 0.4 0.0058 15.9 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 OAG01104.1 - 0.0035 17.1 0.5 0.019 14.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.14 OAG01104.1 - 0.0059 15.9 0.4 0.02 14.1 0.0 1.9 2 0 0 2 2 2 1 KAP family P-loop domain Ge1_WD40 PF16529.5 OAG01104.1 - 0.0087 15.1 0.0 0.028 13.4 0.0 1.8 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_helicase PF00910.22 OAG01104.1 - 0.015 15.7 0.1 0.094 13.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PIF1 PF05970.14 OAG01104.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 OAG01104.1 - 0.018 15.6 0.2 0.078 13.5 0.0 2.1 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 OAG01104.1 - 0.019 14.9 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 OAG01104.1 - 0.023 14.4 0.1 0.053 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG01104.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 OAG01104.1 - 0.063 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OAG01104.1 - 0.14 11.3 0.0 0.41 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 OAG01104.1 - 0.17 11.8 0.1 0.56 10.1 0.1 1.9 1 1 0 1 1 1 0 NTPase PHD_Oberon PF07227.11 OAG01105.1 - 0.025 14.5 2.3 0.043 13.7 2.3 1.4 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein Sgf11 PF08209.11 OAG01105.1 - 0.12 12.0 0.2 0.12 12.0 0.2 3.0 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) OrsD PF12013.8 OAG01105.1 - 0.14 12.6 5.9 0.47 10.9 0.1 2.3 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1272 PF06906.11 OAG01105.1 - 0.25 11.5 3.4 0.35 11.0 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 OAG01105.1 - 9.7 6.3 8.3 43 4.3 8.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon CFEM PF05730.11 OAG01106.1 - 5.2e-12 45.7 13.2 8.3e-12 45.0 13.2 1.3 1 0 0 1 1 1 1 CFEM domain ALMT PF11744.8 OAG01106.1 - 5.7 5.6 10.1 10 4.8 5.6 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter TRI12 PF06609.13 OAG01108.1 - 3.1e-60 204.2 26.8 4e-60 203.9 26.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG01108.1 - 1.8e-21 76.5 61.7 1.8e-21 76.5 61.7 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG01108.1 - 5e-09 35.5 8.4 5e-09 35.5 8.4 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter Ldh_1_C PF02866.18 OAG01109.1 - 3.5e-45 153.9 0.0 1.4e-44 151.9 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAG01109.1 - 1.2e-42 145.3 0.0 1.8e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG01109.1 - 0.0028 16.7 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Carn_acyltransf PF00755.20 OAG01111.1 - 4.2e-207 689.4 0.0 4.8e-207 689.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Chitin_bind_1 PF00187.19 OAG01112.1 - 1.6e-05 25.3 25.1 1.6e-05 25.3 25.1 3.3 2 2 1 3 3 3 1 Chitin recognition protein CHAT PF12770.7 OAG01113.1 - 1.3e-28 100.2 0.0 2.3e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 CHAT domain LIP PF03583.14 OAG01115.1 - 2.9e-53 181.0 0.1 3.9e-53 180.6 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase adh_short PF00106.25 OAG01116.1 - 9.3e-18 64.4 0.0 5.4e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01116.1 - 6.7e-12 45.5 0.3 6e-11 42.3 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAG01116.1 - 1.3e-07 31.7 0.1 2e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG01116.1 - 5e-06 26.2 0.0 7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG01116.1 - 7.5e-06 26.0 0.1 1.2e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 OAG01116.1 - 0.0096 15.5 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 OAG01116.1 - 0.02 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 OAG01116.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SGL PF08450.12 OAG01117.1 - 3.8e-05 23.4 0.0 6.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OAG01117.1 - 0.15 12.2 1.3 3 8.1 0.0 3.3 4 0 0 4 4 4 0 NHL repeat SKG6 PF08693.10 OAG01119.1 - 6.7e-06 25.4 0.1 1.5e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG01119.1 - 0.00055 20.1 1.4 0.001 19.2 1.4 1.5 1 0 0 1 1 1 1 Podoplanin CYYR1 PF10873.8 OAG01119.1 - 0.029 14.8 0.3 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 p450 PF00067.22 OAG01121.1 - 3.1e-66 224.0 0.0 3.7e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Whi5 PF08528.11 OAG01122.1 - 7.1e-13 47.9 0.2 1.1e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 Whi5 like Filaggrin PF03516.13 OAG01122.1 - 3.5 8.4 8.7 11 6.8 2.1 3.6 3 0 0 3 3 3 0 Filaggrin Pyr_redox_2 PF07992.14 OAG01124.1 - 3.7e-07 29.7 0.0 0.00095 18.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 OAG01127.1 - 0.027 13.9 0.0 0.027 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Palm_thioest PF02089.15 OAG01128.1 - 6.3e-76 255.4 0.0 7.4e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 OAG01128.1 - 0.027 14.0 0.0 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 2) DUF915 PF06028.11 OAG01128.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L1 PF00687.21 OAG01129.1 - 5e-60 202.7 6.3 5e-60 202.7 6.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family CDC45 PF02724.14 OAG01129.1 - 6.9 4.8 12.8 0.2 9.9 5.9 1.8 2 0 0 2 2 2 0 CDC45-like protein AMH_N PF04709.12 OAG01130.1 - 0.62 8.9 2.9 1 8.2 2.9 1.3 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region ubiquitin PF00240.23 OAG01131.1 - 1.2e-33 114.6 0.6 1.7e-33 114.2 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG01131.1 - 7.5e-16 57.7 0.7 1e-15 57.3 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L40e PF01020.17 OAG01131.1 - 6.2e-06 26.0 0.8 1.1e-05 25.3 0.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Ubiquitin_2 PF14560.6 OAG01131.1 - 8e-05 23.0 0.1 0.00025 21.4 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG01131.1 - 0.0099 16.0 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OAG01131.1 - 0.01 15.7 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAG01131.1 - 0.012 15.9 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 OAG01131.1 - 0.072 13.7 0.1 0.11 13.0 0.1 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAG01131.1 - 0.073 13.1 1.0 10 6.3 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain zf-RRN7 PF11781.8 OAG01132.1 - 1.1e-05 25.0 1.8 1.9e-05 24.2 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5a PF01287.20 OAG01133.1 - 5e-29 100.2 0.9 6.8e-29 99.8 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OAG01133.1 - 0.03 14.3 0.1 0.062 13.3 0.0 1.6 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 OAG01134.1 - 1.4e-125 419.9 0.0 1.8e-125 419.6 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OAG01134.1 - 4.9e-06 25.2 0.1 6.8e-06 24.8 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Xrn1_D3 PF18194.1 OAG01134.1 - 0.0033 17.5 0.1 0.0099 16.0 0.1 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Pdase_C33_assoc PF14756.6 OAG01135.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase_C33-associated domain RCR PF12273.8 OAG01137.1 - 0.019 15.6 3.3 0.019 15.6 0.1 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Ctr PF04145.15 OAG01137.1 - 0.021 15.5 0.0 0.03 15.0 0.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Ank_2 PF12796.7 OAG01138.1 - 9.4e-65 215.2 17.9 1.5e-10 41.6 0.1 10.2 4 3 7 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG01138.1 - 3.7e-47 158.1 18.8 1.6e-07 31.7 0.0 14.6 10 5 5 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG01138.1 - 2.2e-46 150.5 19.7 0.00069 19.9 0.0 17.5 20 0 0 20 20 20 11 Ankyrin repeat Ank_5 PF13857.6 OAG01138.1 - 2.3e-44 148.9 28.2 1.3e-06 28.6 0.1 14.4 8 4 6 15 15 15 9 Ankyrin repeats (many copies) Ank PF00023.30 OAG01138.1 - 8.9e-41 136.6 40.4 6.9e-05 23.1 0.2 16.0 16 1 1 17 17 17 11 Ankyrin repeat Dus PF01207.17 OAG01140.1 - 4e-36 124.7 0.1 9.7e-26 90.6 0.2 2.9 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 OAG01140.1 - 0.0026 17.5 1.0 0.0026 17.5 1.0 2.7 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAG01140.1 - 0.0031 17.4 9.3 0.068 13.1 0.6 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG01140.1 - 0.011 15.8 12.2 0.35 11.0 1.4 2.7 2 0 0 2 2 2 0 Zinc finger domain Bap31 PF05529.12 OAG01141.1 - 6.1e-50 168.6 5.8 8.6e-50 168.1 5.8 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 OAG01141.1 - 3.9e-12 46.0 0.5 6.8e-12 45.2 0.1 1.6 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Lebercilin PF15619.6 OAG01141.1 - 0.0012 18.5 0.6 0.0017 18.0 0.6 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 OAG01141.1 - 0.011 15.5 4.1 0.15 11.9 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator Csm1_N PF18504.1 OAG01141.1 - 0.027 14.8 0.6 0.057 13.8 0.1 1.7 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 OAG01141.1 - 0.056 12.3 0.5 0.078 11.8 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 OAG01141.1 - 0.064 13.6 0.3 4 7.9 0.0 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper She9_MDM33 PF05546.11 OAG01141.1 - 0.17 11.7 0.2 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family SlyX PF04102.12 OAG01141.1 - 0.19 12.4 1.7 0.43 11.2 0.4 2.0 1 1 1 2 2 2 0 SlyX DUF4349 PF14257.6 OAG01141.1 - 6.3 6.2 5.9 0.36 10.3 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Amidase PF01425.21 OAG01142.1 - 6.8e-67 226.4 0.1 1.5e-65 222.0 0.1 2.0 1 1 0 1 1 1 1 Amidase SEEK1 PF15357.6 OAG01142.1 - 0.02 15.1 0.1 0.045 13.9 0.1 1.5 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 PAF-AH_p_II PF03403.13 OAG01143.1 - 5.4e-15 54.8 0.0 2.8e-07 29.4 0.0 2.0 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG01143.1 - 4e-08 32.5 0.0 6.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 OAG01143.1 - 2.2e-05 25.2 1.0 3.1e-05 24.7 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG01143.1 - 0.00048 19.5 0.0 0.044 13.0 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 OAG01143.1 - 0.00053 19.6 0.1 0.00096 18.8 0.1 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 OAG01143.1 - 0.0018 18.0 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAG01143.1 - 0.0049 16.5 0.0 0.0097 15.5 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAG01143.1 - 0.051 13.0 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG01143.1 - 0.077 12.6 1.4 0.62 9.7 0.4 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 OAG01143.1 - 0.12 11.3 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase Zn_clus PF00172.18 OAG01144.1 - 0.17 12.0 0.2 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pec_lyase_C PF00544.19 OAG01145.1 - 2.5e-18 66.4 5.2 1.3e-16 60.9 5.2 2.4 1 1 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 OAG01145.1 - 2e-12 46.8 10.3 2e-12 46.8 10.3 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Beta_helix PF13229.6 OAG01145.1 - 0.0003 20.7 6.3 0.00094 19.1 6.0 2.0 1 1 1 2 2 2 2 Right handed beta helix region Sel1 PF08238.12 OAG01146.1 - 5.3e-35 119.1 30.4 1.9e-07 31.6 0.2 10.9 11 0 0 11 11 11 8 Sel1 repeat TPR_8 PF13181.6 OAG01146.1 - 0.083 13.1 0.1 19 5.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG01146.1 - 0.084 13.7 4.5 9.1 7.4 0.1 5.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG01146.1 - 0.14 12.2 7.2 11 6.3 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Rrn6 PF10214.9 OAG01146.1 - 0.22 10.0 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MFS_1 PF07690.16 OAG01147.1 - 8.7e-34 117.0 49.0 1.7e-33 116.0 49.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG01147.1 - 8.2e-10 38.1 12.6 8.2e-10 38.1 12.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG01147.1 - 0.0001 20.9 23.1 0.00016 20.2 23.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3784 PF12650.7 OAG01147.1 - 0.37 11.0 0.1 0.37 11.0 0.1 5.3 5 1 1 6 6 6 0 Domain of unknown function (DUF3784) SAD_SRA PF02182.17 OAG01149.1 - 1e-29 103.3 0.0 1.8e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain PAF-AH_p_II PF03403.13 OAG01150.1 - 2.3e-46 158.0 0.0 4.2e-46 157.2 0.0 1.4 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG01150.1 - 3.3e-09 36.0 0.0 3.3e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG01150.1 - 3e-06 26.5 0.0 9.3e-06 24.9 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.8 OAG01150.1 - 1.1e-05 24.8 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 OAG01150.1 - 0.0025 17.4 0.0 0.02 14.4 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Thioesterase PF00975.20 OAG01150.1 - 0.017 15.3 0.1 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Thioesterase domain Lipase_3 PF01764.25 OAG01150.1 - 0.037 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ras PF00071.22 OAG01151.1 - 7.8e-41 139.4 0.0 9.6e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG01151.1 - 4.2e-29 101.2 0.0 5.7e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG01151.1 - 9.1e-11 41.5 0.0 4.6e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG01151.1 - 2.3e-05 24.0 0.0 9e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG01151.1 - 5.5e-05 22.6 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG01151.1 - 0.00067 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OAG01151.1 - 0.036 13.8 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OAG01151.1 - 0.11 13.0 0.1 0.29 11.7 0.1 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 OAG01151.1 - 0.11 12.4 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 OAG01151.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 OAG01151.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Tropomodulin PF03250.14 OAG01151.1 - 0.22 11.6 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 Tropomodulin E1-E2_ATPase PF00122.20 OAG01154.1 - 6.6e-50 169.1 1.7 1.5e-49 167.9 1.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 OAG01154.1 - 8e-49 163.9 1.5 1.6e-12 47.7 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 OAG01154.1 - 1.5e-34 120.2 1.2 1.5e-34 120.2 1.2 3.1 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG01154.1 - 0.0002 21.2 1.3 0.0014 18.4 0.5 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase CDCA PF18484.1 OAG01154.1 - 0.0011 18.8 1.3 13 5.6 0.0 3.5 2 1 1 3 3 3 2 Cadmium carbonic anhydrase repeat B12-binding PF02310.19 OAG01154.1 - 0.004 17.2 1.6 8.1 6.5 0.0 5.3 6 0 0 6 6 6 1 B12 binding domain DUF678 PF05077.12 OAG01154.1 - 0.92 9.7 6.6 2.7 8.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF678) PCI PF01399.27 OAG01155.1 - 1.9e-06 28.3 0.0 6.4e-06 26.6 0.0 1.9 2 1 0 2 2 2 1 PCI domain Unpaired PF15972.5 OAG01155.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Unpaired protein DNA_pol_phi PF04931.13 OAG01156.1 - 3.6 5.6 4.7 4.1 5.4 4.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Lactamase_B_2 PF12706.7 OAG01157.1 - 3e-09 36.7 0.0 6.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 OAG01157.1 - 3.3e-06 27.3 0.0 9.5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 OAG01157.1 - 0.0017 18.4 0.3 0.0045 17.0 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily IKKbetaNEMObind PF12179.8 OAG01157.1 - 0.11 12.6 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Glyco_hydro_10 PF00331.20 OAG01158.1 - 1.9e-101 339.4 0.7 2.2e-101 339.1 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 OAG01158.1 - 5.2e-11 42.3 9.6 5.2e-11 42.3 7.7 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 OAG01158.1 - 0.06 13.6 0.4 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 Toxin 7 Histidinol_dh PF00815.20 OAG01159.1 - 4.4e-158 526.6 6.1 7.2e-158 525.9 6.1 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 OAG01159.1 - 5.9e-25 86.9 0.1 1.1e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OAG01159.1 - 2.3e-14 53.6 0.1 2.3e-14 53.6 0.1 2.8 4 0 0 4 4 4 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 OAG01159.1 - 0.0064 16.7 0.4 0.02 15.1 0.4 1.9 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF615 PF04751.14 OAG01159.1 - 0.091 12.7 0.1 3.3 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF615) EHN PF06441.12 OAG01160.1 - 1.1e-34 119.1 0.6 1.9e-34 118.3 0.6 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG01160.1 - 4.3e-14 52.8 0.0 1e-13 51.5 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG01160.1 - 0.0003 21.5 2.1 0.0019 18.9 2.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ada3 PF10198.9 OAG01161.1 - 1.1e-38 132.4 0.0 1.1e-38 132.4 0.0 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.6 OAG01162.1 - 2.4e-12 47.0 6.5 5.1e-12 45.9 6.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG01162.1 - 9.4e-10 38.1 3.1 9.4e-10 38.1 3.1 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG01162.1 - 2.2e-07 30.6 6.1 4.7e-07 29.5 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG01162.1 - 1.2e-06 28.3 3.9 1.2e-06 28.3 3.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG01162.1 - 2.2e-06 27.4 5.2 5.7e-06 26.1 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG01162.1 - 1.9e-05 24.6 2.2 1.9e-05 24.6 2.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG01162.1 - 0.0001 22.5 6.4 0.00053 20.2 6.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAG01162.1 - 0.00015 21.6 3.2 0.00029 20.6 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG01162.1 - 0.0016 18.5 1.0 0.0037 17.3 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAG01162.1 - 0.0079 16.0 10.4 0.5 10.3 10.5 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 TMEM52 PF14979.6 OAG01162.1 - 0.0089 15.9 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Transmembrane 52 zf-RING_4 PF14570.6 OAG01162.1 - 0.0099 15.7 4.8 0.0099 15.7 4.8 1.7 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OAG01162.1 - 0.15 12.2 4.8 0.41 10.8 4.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Neurensin PF14927.6 OAG01162.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Neurensin Zn_ribbon_17 PF17120.5 OAG01162.1 - 0.19 11.4 1.3 0.53 9.9 1.3 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OAG01162.1 - 0.73 9.8 3.3 2.1 8.3 3.3 1.9 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 OAG01162.1 - 3.8 7.9 6.7 0.37 11.1 0.6 2.4 3 0 0 3 3 2 0 RING-like domain zf-P11 PF03854.14 OAG01162.1 - 4.4 7.0 6.5 0.7 9.6 2.2 1.8 2 0 0 2 2 2 0 P-11 zinc finger ADH_N PF08240.12 OAG01163.1 - 2.8e-24 85.1 0.2 2.8e-24 85.1 0.2 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG01163.1 - 3.5e-13 49.7 0.0 5.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG01163.1 - 5.1e-06 26.1 0.3 0.00027 20.5 0.2 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG01163.1 - 0.0056 17.7 0.0 0.0092 17.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAG01163.1 - 0.042 13.1 0.6 0.16 11.2 0.6 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAG01163.1 - 0.045 13.3 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 OAG01163.1 - 0.19 11.0 1.1 0.54 9.5 0.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HAD_2 PF13419.6 OAG01164.1 - 3.7e-10 40.2 0.0 6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG01164.1 - 7e-08 33.0 0.0 2.4e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG01164.1 - 0.00019 21.4 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Aminotran_1_2 PF00155.21 OAG01165.1 - 2.8e-45 155.1 0.0 3.4e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FMN_dh PF01070.18 OAG01166.1 - 7.1e-110 367.3 0.0 8.5e-110 367.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG01166.1 - 1.2e-20 73.4 0.0 2.5e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG01166.1 - 0.00025 20.3 0.1 0.00058 19.1 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 OAG01166.1 - 0.0037 16.7 0.1 0.0079 15.6 0.0 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG01166.1 - 0.013 14.5 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 OAG01166.1 - 0.024 14.0 0.1 2.1 7.6 0.0 2.5 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 OAG01167.1 - 6.1e-32 110.9 21.5 6.1e-32 110.9 21.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 OAG01168.1 - 1e-46 158.6 0.2 2.4e-46 157.3 0.2 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG01168.1 - 1.2e-06 28.2 0.0 1.7e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG01168.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1871 PF08958.10 OAG01168.1 - 0.042 14.2 0.0 5.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) BNR_2 PF13088.6 OAG01169.1 - 1.4e-66 224.6 2.9 1.7e-66 224.4 2.9 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OAG01169.1 - 0.00011 21.6 13.7 0.37 11.0 0.1 4.4 4 0 0 4 4 4 3 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 OAG01169.1 - 0.00083 18.3 3.0 0.44 9.3 0.2 2.8 2 1 0 3 3 3 2 Sortilin, neurotensin receptor 3, Mo-co_dimer PF03404.16 OAG01169.1 - 0.0036 17.3 1.8 4.4 7.3 0.1 3.4 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain CHB_HEX_C PF03174.13 OAG01169.1 - 0.27 11.2 0.8 5.6 7.0 0.1 2.6 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Sugar_tr PF00083.24 OAG01170.1 - 1.4e-93 314.3 22.0 1.6e-93 314.0 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 OAG01170.1 - 2.4e-40 138.6 0.0 6e-39 134.0 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 OAG01170.1 - 8.3e-19 67.7 20.0 8.3e-19 67.7 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 OAG01171.1 - 1.1e-17 64.3 0.0 1.4e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG01171.1 - 6.4e-09 35.2 0.0 7.7e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG01171.1 - 5.8e-08 32.5 0.0 1.6e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG01171.1 - 2.1e-07 30.3 0.0 3.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG01171.1 - 4.6e-05 22.7 0.0 0.027 13.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Ldh_1_N PF00056.23 OAG01171.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAG01171.1 - 0.065 12.4 0.0 0.3 10.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Aldo_ket_red PF00248.21 OAG01172.1 - 1.5e-62 211.5 0.0 2.2e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SBD_N PF07005.11 OAG01172.1 - 1.8e-62 211.0 0.9 2.3e-62 210.7 0.1 1.6 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 OAG01172.1 - 1e-43 149.8 0.1 2.9e-43 148.3 0.1 1.8 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain DHDPS PF00701.22 OAG01173.1 - 3.2e-42 144.2 0.0 4.4e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Membr_traf_MHD PF10540.9 OAG01174.1 - 1.8e-23 83.3 0.5 1.4e-20 74.0 0.5 2.7 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 OAG01174.1 - 1.8e-15 57.1 0.0 3.8e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 OAG01174.1 - 4.3e-05 22.3 0.1 9.4e-05 21.1 0.1 1.5 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) FidL_like PF15941.5 OAG01174.1 - 0.097 13.1 0.1 0.47 10.9 0.0 2.2 2 0 0 2 2 2 0 FidL-like putative membrane protein HLH PF00010.26 OAG01175.1 - 1.6e-07 31.2 0.1 2.8e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Methyltransf_16 PF10294.9 OAG01176.1 - 0.034 13.9 0.0 3 7.5 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase ATHILA PF03078.15 OAG01177.1 - 0.015 14.1 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 ATHILA ORF-1 family TUG-UBL1 PF11470.8 OAG01177.1 - 0.1 12.8 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 TUG ubiquitin-like domain tRNA-synt_2b PF00587.25 OAG01178.1 - 6.5e-33 114.2 0.0 2e-31 109.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG01178.1 - 2.4e-09 37.2 0.0 1.2e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 Anticodon binding domain UQ_con PF00179.26 OAG01179.1 - 8.2e-49 164.9 0.0 9.3e-49 164.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAG01179.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 UEV domain Sipho_tail PF05709.11 OAG01179.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Phage tail protein RWD PF05773.22 OAG01179.1 - 0.16 12.3 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain Cu-oxidase_2 PF07731.14 OAG01181.1 - 0.012 15.3 1.1 0.015 15.0 1.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase zf-RNPHF PF08080.12 OAG01182.1 - 0.15 12.0 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 RNPHF zinc finger DUF1351 PF07083.11 OAG01182.1 - 0.26 11.0 0.0 0.26 11.0 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1351) DUF2237 PF09996.9 OAG01183.1 - 6.2e-37 126.1 0.0 7.8e-37 125.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) YycI PF09648.10 OAG01183.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 YycH protein FAD_binding_3 PF01494.19 OAG01184.1 - 8.9e-12 44.9 0.1 3.6e-11 42.9 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain HTH_26 PF13443.6 OAG01185.1 - 0.036 14.5 0.1 0.068 13.6 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain zf-CCHC PF00098.23 OAG01186.1 - 0.00039 20.4 1.7 0.00089 19.2 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle UDPGP PF01704.18 OAG01187.1 - 3.5e-58 197.2 0.0 5.2e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MR_MLE_C PF13378.6 OAG01187.1 - 2e-39 135.4 0.0 3.2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAG01187.1 - 9.2e-08 32.3 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 OAG01188.1 - 3.5e-27 95.1 3.3 3.8e-27 95.0 0.7 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01188.1 - 6.6e-08 32.5 8.7 1.2e-07 31.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 OAG01189.1 - 1.2e-43 149.4 0.0 1.9e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG01189.1 - 4.9e-24 85.0 0.0 7.1e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 OAG01189.1 - 5.6e-20 72.2 1.8 1.4e-19 70.9 0.1 2.4 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) Kdo PF06293.14 OAG01189.1 - 0.0088 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PMEI PF04043.15 OAG01189.1 - 0.063 13.6 0.2 0.27 11.6 0.1 2.1 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor TFIIF_alpha PF05793.12 OAG01189.1 - 0.46 9.0 2.7 0.71 8.4 2.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PHD PF00628.29 OAG01189.1 - 0.49 10.3 4.3 1.3 9.0 4.3 1.7 1 0 0 1 1 1 0 PHD-finger RRP7 PF12923.7 OAG01190.1 - 7e-25 87.5 0.1 1.2e-24 86.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 OAG01190.1 - 7e-20 71.5 0.0 6.4e-19 68.3 0.0 2.0 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 OAG01190.1 - 0.14 12.0 0.0 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.23 OAG01191.1 - 4.3e-62 209.8 0.1 6.9e-62 209.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG01191.1 - 9.2e-18 64.6 0.0 9.8e-17 61.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG01191.1 - 4.5e-09 36.5 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 OAG01191.1 - 2.3e-08 34.3 1.9 2.3e-08 34.3 1.9 2.8 2 0 0 2 2 2 1 HSA DEAD PF00270.29 OAG01191.1 - 2.7e-06 27.3 0.0 5.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 OAG01191.1 - 0.0032 17.1 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Thg1 PF04446.12 OAG01198.1 - 1.8e-50 170.2 0.0 2.6e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OAG01198.1 - 5.5e-48 162.1 0.1 1e-42 145.2 0.0 2.2 2 0 0 2 2 2 2 Thg1 C terminal domain EF-hand_like PF09279.11 OAG01200.1 - 4.6 7.8 6.2 0.69 10.4 0.4 2.5 2 1 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like adh_short PF00106.25 OAG01201.1 - 3.7e-38 131.0 0.0 4.4e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01201.1 - 7.6e-30 104.2 0.1 9.5e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG01201.1 - 7.3e-11 42.3 2.0 5.4e-10 39.5 2.0 2.1 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.14 OAG01201.1 - 0.039 12.6 0.0 0.063 12.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 OAG01201.1 - 0.11 12.7 0.2 0.27 11.5 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Utp11 PF03998.13 OAG01202.1 - 2.7e-65 220.7 30.9 3.4e-65 220.4 30.9 1.1 1 0 0 1 1 1 1 Utp11 protein Herpes_UL3 PF03369.13 OAG01202.1 - 1 9.9 6.0 3.6 8.1 0.0 2.4 2 1 0 2 2 2 0 Herpesvirus UL3 protein adh_short PF00106.25 OAG01203.1 - 2.7e-17 62.9 0.0 9.2e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01203.1 - 7.7e-08 32.2 0.0 1.2e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG01203.1 - 2.5e-05 24.3 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 KR domain GHMP_kinases_N PF00288.26 OAG01203.1 - 0.016 15.4 0.7 0.075 13.3 0.9 2.0 2 0 0 2 2 2 0 GHMP kinases N terminal domain Sacchrp_dh_NADP PF03435.18 OAG01203.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Metallophos PF00149.28 OAG01204.1 - 1e-10 42.5 3.3 1.4e-10 42.0 3.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EMP70 PF02990.16 OAG01205.1 - 8.5e-186 618.6 5.1 1e-185 618.4 5.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Aldedh PF00171.22 OAG01208.1 - 3.8e-146 487.2 0.0 4.7e-146 486.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG01208.1 - 0.0049 16.0 0.0 0.011 14.9 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF4360 PF14273.6 OAG01209.1 - 2.8e-53 180.4 1.7 3.2e-53 180.2 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ABC_membrane_2 PF06472.15 OAG01210.1 - 1.7e-92 309.6 0.1 3.4e-92 308.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAG01210.1 - 3.2e-15 56.8 0.0 2.1e-14 54.2 0.0 2.3 3 0 0 3 3 3 1 ABC transporter THOC7 PF05615.13 OAG01210.1 - 0.0056 17.0 0.6 0.013 15.7 0.6 1.6 1 0 0 1 1 1 1 Tho complex subunit 7 End3 PF12761.7 OAG01210.1 - 0.019 15.2 0.5 0.034 14.3 0.5 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 AAA_16 PF13191.6 OAG01210.1 - 0.038 14.4 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OAG01210.1 - 0.057 13.9 0.6 8.4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 OAG01210.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 OAG01210.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 OAG01210.1 - 0.16 11.7 0.0 0.71 9.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 OAG01210.1 - 0.17 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 OAG01210.1 - 0.18 12.2 0.1 0.4 11.1 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aminotran_1_2 PF00155.21 OAG01212.1 - 1.2e-16 60.9 0.0 2.5e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG01212.1 - 0.00059 18.5 0.0 0.00084 18.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AAA PF00004.29 OAG01214.1 - 5.3e-41 140.1 0.0 3.4e-12 46.9 0.0 5.7 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 OAG01214.1 - 1e-37 129.7 0.0 3.7e-37 127.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG01214.1 - 1e-25 91.0 26.7 6.1e-24 85.2 0.0 6.5 6 0 0 6 6 4 2 AAA domain AAA_30 PF13604.6 OAG01214.1 - 7e-20 71.6 8.3 9.4e-05 22.2 0.0 6.0 6 0 0 6 6 5 5 AAA domain AAA_19 PF13245.6 OAG01214.1 - 1.6e-18 67.4 0.0 6.1e-09 36.4 0.0 5.5 4 2 1 5 5 5 3 AAA domain AAA_lid_6 PF17866.1 OAG01214.1 - 1.9e-17 63.2 1.7 3.9e-06 27.0 1.3 4.1 3 0 0 3 3 3 2 AAA lid domain AAA_5 PF07728.14 OAG01214.1 - 1.1e-13 51.4 0.6 0.03 14.3 0.0 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG01214.1 - 6.1e-11 42.7 8.7 0.28 11.4 0.0 7.7 5 3 1 6 6 6 2 AAA domain Mg_chelatase PF01078.21 OAG01214.1 - 6.4e-11 42.0 0.3 0.094 12.1 0.0 4.6 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 OAG01214.1 - 1.9e-10 40.9 0.1 0.3 10.8 0.0 6.6 7 0 0 7 7 7 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OAG01214.1 - 1.8e-09 38.2 1.2 1.5 9.2 0.0 5.9 5 0 0 5 5 4 3 AAA ATPase domain AAA_18 PF13238.6 OAG01214.1 - 2.2e-07 31.5 3.2 0.92 10.1 0.0 5.4 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 OAG01214.1 - 2.2e-07 31.2 0.6 6.8 7.1 0.0 5.0 5 0 0 5 5 4 0 RNA helicase ResIII PF04851.15 OAG01214.1 - 4.2e-07 30.1 0.1 0.1 12.6 0.0 5.1 4 1 1 5 5 5 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 OAG01214.1 - 5.9e-07 29.4 0.5 2.2 8.0 0.0 4.7 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OAG01214.1 - 1.5e-06 28.0 7.4 0.75 9.5 0.1 5.7 6 0 0 6 6 5 2 AAA domain AAA_7 PF12775.7 OAG01214.1 - 2.6e-06 27.1 0.8 4.9 6.6 0.0 4.5 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_33 PF13671.6 OAG01214.1 - 6.5e-06 26.4 4.8 2.7 8.1 0.1 5.1 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 OAG01214.1 - 1.8e-05 24.6 0.1 5.8 6.6 0.0 4.7 4 0 0 4 4 4 0 IstB-like ATP binding protein TniB PF05621.11 OAG01214.1 - 1.9e-05 24.2 0.0 10 5.5 0.0 6.1 5 1 1 6 6 6 0 Bacterial TniB protein DUF2075 PF09848.9 OAG01214.1 - 0.00018 20.9 6.5 0.016 14.4 0.0 5.6 4 2 1 6 6 6 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 OAG01214.1 - 0.0002 21.1 1.2 8.1 6.1 0.0 5.1 5 0 0 5 5 5 0 Sigma-54 interaction domain Rad17 PF03215.15 OAG01214.1 - 0.00043 20.3 0.2 1.4 8.8 0.0 3.6 4 0 0 4 4 3 1 Rad17 P-loop domain TsaE PF02367.17 OAG01214.1 - 0.023 14.7 1.2 27 4.8 0.0 4.1 5 0 0 5 5 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 OAG01214.1 - 0.034 13.8 3.1 1.1 8.8 0.1 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Adeno_IVa2 PF02456.15 OAG01214.1 - 0.042 12.6 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 OAG01214.1 - 0.081 12.8 0.5 1.8 8.4 0.1 3.1 3 0 0 3 3 3 0 RsgA GTPase CAP18_C PF12153.8 OAG01214.1 - 0.084 12.8 0.4 0.27 11.1 0.4 1.9 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) UvrD-helicase PF00580.21 OAG01214.1 - 0.086 12.3 0.0 0.086 12.3 0.0 5.5 6 0 0 6 6 4 0 UvrD/REP helicase N-terminal domain NACHT PF05729.12 OAG01214.1 - 0.1 12.5 4.3 41 4.1 0.0 4.3 4 0 0 4 4 4 0 NACHT domain AAA_25 PF13481.6 OAG01214.1 - 0.12 12.0 7.3 7.7 6.0 0.1 4.4 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 OAG01214.1 - 0.45 11.0 10.1 8.8 6.8 0.1 5.0 5 0 0 5 5 4 0 ABC transporter NTPase_1 PF03266.15 OAG01214.1 - 0.55 10.1 6.0 26 4.7 0.0 4.4 5 0 0 5 5 4 0 NTPase AAA_6 PF12774.7 OAG01214.1 - 1.3 7.9 3.3 27 3.6 0.0 3.6 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 OAG01214.1 - 1.4 9.1 15.3 6.2 7.0 0.0 5.1 5 0 0 5 5 4 0 AAA domain adh_short_C2 PF13561.6 OAG01216.1 - 3.8e-18 65.9 0.0 4.5e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG01216.1 - 6.3e-18 64.9 0.0 7e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase FAD_binding_4 PF01565.23 OAG01217.1 - 2.2e-21 76.0 4.7 3.8e-21 75.3 3.0 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG01217.1 - 0.00089 19.3 0.3 0.0017 18.4 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 OAG01218.1 - 5.7e-33 114.3 33.2 7e-33 114.0 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PetM PF08041.11 OAG01218.1 - 0.0034 16.9 3.0 0.013 15.1 3.0 2.0 1 0 0 1 1 1 1 PetM family of cytochrome b6f complex subunit 7 AtuA PF07287.11 OAG01219.1 - 1.9e-127 424.8 0.0 2.2e-127 424.6 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA CoA_transf_3 PF02515.17 OAG01220.1 - 8.8e-35 120.5 0.0 3.2e-33 115.4 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Acetyltransf_3 PF13302.7 OAG01221.1 - 6.9e-18 65.7 0.1 1.6e-17 64.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG01221.1 - 0.0082 16.1 0.0 0.035 14.1 0.0 2.0 2 1 0 2 2 2 1 FR47-like protein Lactamase_B_3 PF13483.6 OAG01222.1 - 2.9e-05 24.0 0.0 6.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAG01222.1 - 0.0013 18.3 0.7 0.005 16.4 0.7 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HET PF06985.11 OAG01223.1 - 5.9e-23 81.8 2.9 3.2e-22 79.4 2.9 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4848 PF16140.5 OAG01223.1 - 0.051 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) DnaJ PF00226.31 OAG01225.1 - 9.5e-11 41.7 0.2 1.6e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Kelch_3 PF13415.6 OAG01226.1 - 5.3e-29 99.9 15.8 1.7e-07 31.3 0.1 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG01226.1 - 1.3e-25 89.1 7.7 1.1e-09 38.2 0.1 6.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG01226.1 - 2.3e-20 72.1 4.6 0.0006 20.0 0.0 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OAG01226.1 - 5.1e-18 64.4 3.7 0.017 14.7 0.0 6.7 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 OAG01226.1 - 6e-16 58.0 5.1 0.0054 16.7 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OAG01226.1 - 1.6e-10 40.6 10.1 0.75 9.9 0.0 6.8 6 1 0 6 6 6 5 Kelch motif PQQ_3 PF13570.6 OAG01226.1 - 0.086 13.4 9.5 1.3 9.7 1.1 4.5 4 1 1 5 5 5 0 PQQ-like domain Response_reg PF00072.24 OAG01229.1 - 1.3e-25 89.7 0.1 2.6e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG01229.1 - 3.5e-24 85.5 0.1 8.7e-23 81.0 0.1 2.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG01229.1 - 1.6e-13 50.4 0.0 5.2e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 OAG01229.1 - 0.0001 22.2 1.0 0.00028 20.7 1.0 1.7 1 0 0 1 1 1 1 Cache domain HAMP PF00672.25 OAG01229.1 - 0.00038 20.8 0.5 0.82 10.1 0.1 2.8 2 0 0 2 2 2 2 HAMP domain 2-oxogl_dehyd_N PF16078.5 OAG01229.1 - 0.013 15.0 0.2 0.023 14.3 0.2 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Spore_YhcN_YlaJ PF09580.10 OAG01229.1 - 0.043 13.9 0.7 0.093 12.8 0.0 1.9 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) COG5 PF10392.9 OAG01229.1 - 0.07 13.3 0.2 0.19 11.9 0.2 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 MFS_1 PF07690.16 OAG01230.1 - 1.8e-06 27.1 42.6 0.00015 20.8 40.2 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.21 OAG01231.1 - 6.1e-17 61.8 0.0 7.6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Esterase_phd PF10503.9 OAG01232.1 - 4.7e-22 78.6 0.6 6.8e-22 78.0 0.6 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG01232.1 - 9.5e-12 44.8 0.3 1.3e-11 44.3 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OAG01232.1 - 0.012 14.5 0.3 0.016 14.1 0.3 1.1 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG01232.1 - 0.032 14.1 0.1 0.15 11.9 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG01232.1 - 0.11 11.8 0.2 0.74 9.0 0.2 1.9 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Catalase-rel PF06628.12 OAG01233.1 - 1.3e-06 28.5 0.0 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Catalase-related immune-responsive CRM1_repeat_2 PF18784.1 OAG01234.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Meth_synt_2 PF01717.18 OAG01235.1 - 3.4e-12 46.3 0.0 4.8e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG01235.1 - 0.00011 21.8 0.0 0.005 16.4 0.0 2.6 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Macoilin PF09726.9 OAG01236.1 - 8.1 4.9 18.6 15 4.0 18.6 1.4 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 OAG01237.1 - 5e-32 111.2 31.0 5e-32 111.2 31.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily RseC_MucC PF04246.12 OAG01237.1 - 3.5 7.6 7.1 4.4 7.3 0.2 3.3 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Cupin_2 PF07883.11 OAG01238.1 - 4.8e-12 45.4 0.8 4.8e-12 45.4 0.8 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 OAG01238.1 - 4e-07 29.8 0.0 5.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG01238.1 - 0.0014 18.6 0.1 0.0014 18.6 0.1 1.6 2 0 0 2 2 2 1 AraC-like ligand binding domain JmjC PF02373.22 OAG01238.1 - 0.018 15.5 0.2 0.093 13.2 0.2 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase FdtA PF05523.11 OAG01238.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal DUF932 PF06067.11 OAG01239.1 - 0.054 13.3 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DHDPS PF00701.22 OAG01240.1 - 1.1e-31 109.6 0.0 1.6e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AA_permease PF00324.21 OAG01241.1 - 7.6e-121 404.0 40.7 9.2e-121 403.7 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG01241.1 - 9.4e-35 120.2 42.6 1.1e-34 120.1 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease PsbL PF02419.17 OAG01241.1 - 0.051 13.6 0.7 0.27 11.2 0.7 2.3 1 0 0 1 1 1 0 PsbL protein Fungal_trans PF04082.18 OAG01242.1 - 1e-05 24.8 1.5 1.6e-05 24.1 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01242.1 - 2.9e-05 24.1 5.9 5.8e-05 23.1 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rootletin PF15035.6 OAG01242.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3830 PF12903.7 OAG01243.1 - 2.9e-27 95.1 0.0 3.1e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) TauD PF02668.16 OAG01244.1 - 4.5e-47 161.1 0.4 5.6e-47 160.8 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Atg29_N PF18388.1 OAG01244.1 - 0.051 13.4 0.3 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Atg29 N-terminal domain AA_permease_2 PF13520.6 OAG01246.1 - 5.4e-58 196.8 50.7 6.4e-58 196.6 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG01246.1 - 2.4e-25 89.1 43.1 3.3e-25 88.6 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease Glucosamine_iso PF01182.20 OAG01247.1 - 1.3e-21 77.6 0.0 2.2e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 OAG01247.1 - 0.0036 16.5 0.1 0.0059 15.8 0.1 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain Zn_clus PF00172.18 OAG01248.1 - 7.5e-07 29.2 7.6 1.2e-06 28.5 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_1 PF00349.21 OAG01249.1 - 1.3e-64 217.8 0.0 1.8e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 OAG01249.1 - 5.9e-64 215.8 0.0 1.1e-47 162.5 0.0 2.3 2 0 0 2 2 2 2 Hexokinase DUF5601 PF18151.1 OAG01249.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) bZIP_1 PF00170.21 OAG01251.1 - 1.7e-06 28.0 5.9 2.9e-06 27.3 5.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG01251.1 - 4.5e-05 23.4 7.1 8.8e-05 22.5 7.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG01251.1 - 0.0023 18.4 3.4 0.0051 17.3 3.4 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor RTA1 PF04479.13 OAG01253.1 - 1e-74 250.7 11.8 1e-74 250.7 11.8 1.5 2 0 0 2 2 2 1 RTA1 like protein ISK_Channel PF02060.15 OAG01253.1 - 0.24 11.1 1.7 0.23 11.2 0.2 2.0 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Caveolin PF01146.17 OAG01253.1 - 0.89 9.5 5.0 0.78 9.7 2.8 2.0 1 1 1 2 2 2 0 Caveolin Zn_clus PF00172.18 OAG01254.1 - 9.1e-08 32.1 9.6 2.2e-07 30.9 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG01254.1 - 0.0059 15.5 0.3 0.0088 14.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_106 PF17132.4 OAG01255.1 - 2.6e-28 98.8 0.0 4.9e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 alpha-L-rhamnosidase AA_permease PF00324.21 OAG01257.1 - 1.9e-102 343.4 34.9 2.3e-102 343.1 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG01257.1 - 3e-24 85.7 35.7 3.7e-24 85.3 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 OAG01257.1 - 0.15 12.2 2.3 30 4.7 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function PAC4 PF16093.5 OAG01258.1 - 0.5 10.6 3.4 2.6 8.3 2.4 2.6 2 1 0 2 2 2 0 Proteasome assembly chaperone 4 Zn_clus PF00172.18 OAG01259.1 - 6.7e-09 35.7 6.9 1.2e-08 35.0 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG01259.1 - 5.1e-06 25.6 6.6 1.6e-05 23.9 6.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain MMS19_C PF12460.8 OAG01259.1 - 0.019 14.1 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal K_channel_TID PF07941.11 OAG01260.1 - 0.32 11.5 8.6 0.47 10.9 8.6 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CFEM PF05730.11 OAG01261.1 - 0.052 13.7 12.8 0.11 12.6 12.8 1.6 1 0 0 1 1 1 0 CFEM domain Abhydrolase_1 PF00561.20 OAG01263.1 - 2.2e-17 63.5 0.3 3.1e-17 63.1 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG01263.1 - 2.1e-15 58.0 1.5 2.6e-15 57.6 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG01263.1 - 2e-13 50.2 0.1 2.2e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG01263.1 - 0.00015 20.6 0.1 0.00022 20.0 0.1 1.2 1 0 0 1 1 1 1 Ndr family SARAF PF06682.12 OAG01264.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.6 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Git3 PF11710.8 OAG01264.1 - 0.21 11.3 0.1 0.31 10.8 0.1 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Gram_pos_anchor PF00746.21 OAG01264.1 - 0.21 11.6 0.2 0.53 10.3 0.2 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif V-SNARE_C PF12352.8 OAG01265.1 - 3.5e-13 49.6 0.3 9.6e-13 48.2 0.2 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAG01265.1 - 0.00036 20.4 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 Sec20 Pox_EPC_I2-L1 PF12575.8 OAG01265.1 - 0.1 12.8 0.2 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Tmemb_cc2 PF10267.9 OAG01267.1 - 6.6 5.8 8.8 7.9 5.5 8.8 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_S24 PF00717.23 OAG01269.1 - 2.4e-07 30.6 1.2 1.1e-06 28.5 1.2 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 OAG01269.1 - 1.8e-05 24.6 0.0 9e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 GLTP PF08718.11 OAG01270.1 - 1e-47 162.2 0.0 1.3e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Iso_dh PF00180.20 OAG01271.1 - 3e-98 329.2 0.0 3.7e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 OAG01271.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Methyltransf_32 PF13679.6 OAG01272.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAG01272.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pirin PF02678.16 OAG01273.1 - 1.1e-26 92.9 0.2 1.8e-26 92.2 0.2 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 OAG01273.1 - 0.00019 21.5 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 OAG01273.1 - 0.0011 18.6 1.3 0.019 14.7 0.1 2.6 2 1 0 2 2 2 1 Cupin domain zinc_ribbon_2 PF13240.6 OAG01275.1 - 7.9e-05 22.2 7.1 0.00026 20.6 7.2 1.8 1 1 1 2 2 2 2 zinc-ribbon domain DZR PF12773.7 OAG01275.1 - 0.00035 20.5 3.6 0.00059 19.8 3.6 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-C4H2 PF10146.9 OAG01275.1 - 0.0044 17.4 1.2 0.0057 17.0 1.2 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein zf-ribbon_3 PF13248.6 OAG01275.1 - 0.0077 15.6 6.5 0.014 14.8 6.4 1.6 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 OAG01275.1 - 0.009 16.7 3.4 0.012 16.4 3.4 1.3 1 1 0 1 1 1 1 zinc-ribbon family TackOD1 PF18551.1 OAG01275.1 - 0.013 15.2 0.6 0.015 14.9 0.6 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-tcix PF14952.6 OAG01275.1 - 0.21 11.2 5.9 2.3 7.9 0.8 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-NADH-PPase PF09297.11 OAG01275.1 - 0.39 10.4 8.3 1.9 8.2 2.7 2.5 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RecR PF02132.15 OAG01275.1 - 0.45 10.1 4.2 3.9 7.1 4.2 2.2 1 1 0 1 1 1 0 RecR protein Nudix_N_2 PF14803.6 OAG01275.1 - 0.74 9.8 0.1 0.74 9.8 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal UPF0547 PF10571.9 OAG01275.1 - 1.4 9.1 7.2 3 8.0 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.11 OAG01275.1 - 1.9 8.7 6.8 4.2 7.6 0.8 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Spore_coat_CotO PF14153.6 OAG01275.1 - 3.1 7.7 7.4 4.3 7.2 7.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO LigB PF02900.18 OAG01279.1 - 4.1e-35 121.2 0.0 5e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CDC27 PF09507.10 OAG01280.1 - 0.002 17.6 12.3 0.002 17.6 12.3 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 OAG01280.1 - 0.07 12.9 5.5 0.077 12.8 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DTHCT PF08070.11 OAG01280.1 - 0.19 12.5 20.3 2.4 9.0 11.4 2.4 1 1 1 2 2 2 0 DTHCT (NUC029) region OMPdecase PF00215.24 OAG01281.1 - 8e-77 257.8 0.0 9.8e-77 257.5 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Cupin_3 PF05899.12 OAG01283.1 - 1.4e-06 27.9 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) DsbC_N PF10411.9 OAG01283.1 - 0.0038 16.6 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus EutQ PF06249.12 OAG01283.1 - 0.021 14.6 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 OAG01283.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Abhydrolase_6 PF12697.7 OAG01284.1 - 0.00079 20.1 1.2 0.002 18.8 0.4 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG01284.1 - 0.0022 17.7 0.2 0.0072 16.0 0.0 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold zf-C2H2 PF00096.26 OAG01288.1 - 0.0088 16.4 12.3 0.13 12.7 1.0 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type Rpr2 PF04032.16 OAG01291.1 - 0.0095 16.2 1.0 0.034 14.4 1.0 1.9 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain CHORD PF04968.12 OAG01291.1 - 0.12 13.1 2.1 0.28 11.9 2.1 1.7 1 1 0 1 1 1 0 CHORD P_C PF06640.11 OAG01291.1 - 0.62 10.2 5.7 18 5.4 5.7 2.4 1 1 0 1 1 1 0 P protein C-terminus DAO PF01266.24 OAG01294.1 - 5.4e-28 98.6 0.0 6.7e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG01294.1 - 1.7e-05 24.8 0.1 0.18 11.8 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG01294.1 - 0.00047 19.5 0.1 0.12 11.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG01294.1 - 0.00069 18.6 0.1 0.0046 15.9 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 OAG01294.1 - 0.0036 16.4 0.0 0.0089 15.2 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A p450 PF00067.22 OAG01296.1 - 3.8e-29 101.8 0.0 3.4e-22 78.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 CN_hydrolase PF00795.22 OAG01297.1 - 4.3e-31 108.2 0.1 4.9e-26 91.6 0.2 2.3 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase FAM163 PF15069.6 OAG01300.1 - 0.00027 21.4 0.0 0.00027 21.4 0.0 2.0 2 0 0 2 2 2 1 FAM163 family SR-25 PF10500.9 OAG01300.1 - 0.0015 18.2 30.6 0.0027 17.4 30.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 OAG01300.1 - 0.011 16.6 7.6 0.76 10.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Hamartin PF04388.12 OAG01300.1 - 0.039 12.6 11.7 0.045 12.4 11.7 1.0 1 0 0 1 1 1 0 Hamartin protein Med19 PF10278.9 OAG01300.1 - 0.13 12.2 30.2 0.26 11.2 30.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SpoIIIAH PF12685.7 OAG01300.1 - 0.48 10.2 9.1 2.9 7.7 9.1 1.9 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF1764 PF08576.10 OAG01300.1 - 0.61 11.0 20.0 1.4 9.9 18.3 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) V_ATPase_I PF01496.19 OAG01300.1 - 1.1 7.1 4.7 1.8 6.4 4.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rxt3 PF08642.10 OAG01300.1 - 2 9.2 9.0 19 6.0 5.8 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 HA2 PF04408.23 OAG01300.1 - 2.4 8.5 6.6 4.6 7.6 6.6 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) EOS1 PF12326.8 OAG01300.1 - 3.3 7.6 5.1 2.5 8.0 4.1 1.4 1 1 0 1 1 1 0 N-glycosylation protein Topoisom_I_N PF02919.15 OAG01300.1 - 4.6 6.7 15.5 3.7 7.0 13.5 1.7 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Flp1_like PF16982.5 OAG01300.1 - 7 6.1 9.1 11 5.5 9.1 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Methyltransf_25 PF13649.6 OAG01301.1 - 3.1e-08 34.2 0.0 8.8e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG01301.1 - 8.2e-07 28.9 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG01301.1 - 8.5e-06 25.7 0.0 3.8e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG01301.1 - 3e-05 24.7 0.0 7.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG01301.1 - 8e-05 23.2 0.0 0.00021 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG01301.1 - 0.0006 19.2 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG01301.1 - 0.0041 16.5 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 OAG01301.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 OAG01301.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 OAG01301.1 - 0.03 14.1 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OAG01301.1 - 0.035 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Choline_transpo PF04515.12 OAG01303.1 - 2.9e-85 286.3 27.3 2.9e-85 286.3 27.3 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter Mannitol_dh_C PF08125.13 OAG01304.1 - 9.4e-44 149.7 0.2 1.4e-43 149.1 0.2 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 OAG01304.1 - 9.7e-20 71.3 0.2 7.2e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 OAG01304.1 - 0.0092 15.9 1.6 0.044 13.7 0.1 2.5 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG01304.1 - 0.089 12.4 0.9 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.18 OAG01307.1 - 6.1e-05 23.0 10.7 6.1e-05 23.0 10.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamitin PF04912.14 OAG01307.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Dynamitin CEP19 PF14933.6 OAG01309.1 - 0.18 12.1 1.1 0.25 11.6 1.1 1.2 1 0 0 1 1 1 0 CEP19-like protein CorA PF01544.18 OAG01310.1 - 6.9e-10 38.7 0.7 1.1e-09 38.0 0.7 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_47 PF01532.20 OAG01313.1 - 9.1e-29 100.6 0.0 9.9e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease_2 PF13520.6 OAG01316.1 - 2.1e-53 181.7 38.6 2.5e-53 181.5 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG01316.1 - 2.5e-31 108.8 29.7 4.3e-31 108.0 29.7 1.3 1 0 0 1 1 1 1 Amino acid permease AgrD PF05931.11 OAG01316.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein DUF2456 PF10445.9 OAG01316.1 - 0.59 10.3 9.9 4.5 7.4 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) DUF3278 PF11683.8 OAG01316.1 - 1.9 8.6 4.6 1.9 8.6 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF3328 PF11807.8 OAG01318.1 - 2e-25 89.8 0.4 4.4e-25 88.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_7 PF13508.7 OAG01319.1 - 1.4e-08 35.0 0.0 3.6e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG01319.1 - 4.1e-08 33.5 0.0 6.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG01319.1 - 9.1e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2961 PF11175.8 OAG01319.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) AstA PF04958.12 OAG01319.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit GST_N_4 PF17172.4 OAG01321.1 - 1.6e-18 67.2 0.0 2.5e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OAG01321.1 - 1.2e-06 28.2 0.0 3.2e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG01321.1 - 0.0031 17.5 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG01321.1 - 0.041 14.3 0.1 0.27 11.7 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 OAG01321.1 - 0.055 13.8 0.0 0.088 13.1 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_2 PF13409.6 OAG01321.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribonuc_L-PSP PF01042.21 OAG01322.1 - 1.1e-31 109.4 0.0 1.2e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HET PF06985.11 OAG01323.1 - 1.2e-22 80.8 1.9 1.2e-22 80.8 1.9 2.3 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) TMEM154 PF15102.6 OAG01324.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family SIT PF15330.6 OAG01324.1 - 0.0035 17.8 0.8 0.0073 16.8 0.1 1.9 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT DUF4834 PF16118.5 OAG01324.1 - 0.04 14.9 0.0 0.079 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) BatD PF13584.6 OAG01324.1 - 0.047 12.5 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Herpes_gE PF02480.16 OAG01324.1 - 0.063 12.0 0.0 0.11 11.2 0.0 1.4 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.16 OAG01326.1 - 4.9e-40 137.5 28.5 4.9e-40 137.5 28.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG01326.1 - 4.5e-13 48.9 19.2 6.5e-13 48.3 19.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4519 PF15012.6 OAG01326.1 - 0.95 9.7 0.0 0.95 9.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Glyco_hydro_cc PF11790.8 OAG01327.1 - 1.2e-63 214.9 0.0 1.4e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ribosomal_L22 PF00237.19 OAG01328.1 - 1.1e-40 138.0 1.0 2.2e-40 137.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.17 OAG01329.1 - 2.9e-103 343.9 0.0 3.5e-103 343.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OAG01329.1 - 5e-05 23.1 0.0 7.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 OAG01329.1 - 0.021 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 OAG01329.1 - 0.026 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_C48 PF02902.19 OAG01332.1 - 0.24 11.2 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF3992 PF13157.6 OAG01333.1 - 0.075 13.8 0.4 0.71 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3992) HhH-GPD PF00730.25 OAG01334.1 - 2.5e-10 40.8 0.0 3.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG01334.1 - 0.039 13.8 0.2 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif SNF2_N PF00176.23 OAG01335.1 - 5.7e-25 87.8 0.0 8.7e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG01335.1 - 7.7e-17 61.6 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OAG01335.1 - 2.4e-06 27.0 0.1 6.2e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PhyH PF05721.13 OAG01336.1 - 4e-05 24.0 0.1 8.9e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RdRP PF05183.12 OAG01337.1 - 9.4e-131 437.3 0.0 1.5e-130 436.6 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase TCTP PF00838.17 OAG01338.1 - 5.2e-72 241.6 1.7 5.8e-72 241.4 1.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF1839 PF08893.10 OAG01338.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) FA_hydroxylase PF04116.13 OAG01339.1 - 8.1e-24 84.5 12.0 8.1e-24 84.5 12.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-RING_2 PF13639.6 OAG01340.1 - 3.3e-11 43.3 6.4 7.7e-11 42.2 6.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG01340.1 - 3.3e-07 30.2 3.1 3.3e-07 30.2 3.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG01340.1 - 3.5e-07 30.4 6.1 8e-07 29.3 6.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG01340.1 - 6e-07 29.3 5.5 1.2e-06 28.4 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG01340.1 - 6.7e-07 29.1 3.4 1.3e-06 28.1 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG01340.1 - 2.2e-06 27.4 6.6 4e-06 26.6 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG01340.1 - 1.3e-05 25.0 5.6 2.5e-05 24.0 5.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OAG01340.1 - 2.2e-05 24.4 2.4 4.3e-05 23.5 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OAG01340.1 - 0.0002 21.5 4.5 0.00036 20.6 4.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAG01340.1 - 0.0004 20.2 6.5 0.00085 19.1 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG01340.1 - 0.0025 17.5 10.5 0.017 14.8 8.3 2.4 2 0 0 2 2 2 1 RING-like zinc finger RINGv PF12906.7 OAG01340.1 - 0.014 15.5 2.2 0.054 13.6 2.2 2.1 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 OAG01340.1 - 0.3 10.9 2.9 0.61 10.0 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 OAG01340.1 - 0.36 10.5 7.8 0.086 12.5 3.8 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Isochorismatase PF00857.20 OAG01341.1 - 4.9e-40 137.6 0.0 5.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family HR_lesion PF05514.11 OAG01342.1 - 0.068 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 HR-like lesion-inducing TIP41 PF04176.13 OAG01343.1 - 0.037 13.5 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 TIP41-like family UspA1_rep PF18792.1 OAG01344.1 - 0.048 14.1 1.9 0.048 14.1 1.9 2.2 2 0 0 2 2 2 0 Ubiquitous surface protein adhesin repeat zf-AN1 PF01428.16 OAG01345.1 - 4.6e-22 77.9 23.1 2e-11 43.9 8.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger zf-C5HC2 PF02928.16 OAG01345.1 - 0.017 15.5 11.2 0.084 13.3 1.0 2.6 2 0 0 2 2 2 0 C5HC2 zinc finger IBR PF01485.21 OAG01345.1 - 0.053 13.8 16.5 0.87 9.9 6.0 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 OAG01345.1 - 0.65 10.4 12.8 0.95 9.9 2.9 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 OAG01345.1 - 9.1 6.6 14.4 2.9 8.2 4.4 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain ADH_zinc_N PF00107.26 OAG01346.1 - 1.4e-09 38.0 0.1 2.5e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG01346.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG01346.1 - 0.00082 20.4 0.0 0.0014 19.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG01346.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01347.1 - 1.1e-54 185.5 0.2 2e-54 184.6 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG01347.1 - 2.2e-49 167.6 1.0 2.7e-49 167.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG01347.1 - 3.6e-17 62.9 0.4 4.6e-17 62.5 0.4 1.1 1 0 0 1 1 1 1 KR domain Cofilin_ADF PF00241.20 OAG01347.1 - 0.00081 19.2 0.0 0.0016 18.2 0.0 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Epimerase PF01370.21 OAG01347.1 - 0.0011 18.4 0.4 0.0048 16.4 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 OAG01347.1 - 0.018 14.9 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 OAG01347.1 - 0.052 13.5 0.2 1 9.4 0.3 2.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 OAG01347.1 - 0.052 12.7 0.1 0.064 12.4 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 OAG01347.1 - 0.078 12.3 0.1 2.2 7.6 0.0 2.3 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 OAG01347.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Methyltransf_11 PF08241.12 OAG01347.1 - 0.14 12.8 0.1 0.49 11.1 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_4 PF01565.23 OAG01348.1 - 5.9e-20 71.4 0.9 1.2e-19 70.4 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG01348.1 - 4.9e-06 26.5 0.0 9.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Aldo_ket_red PF00248.21 OAG01349.1 - 1.1e-43 149.5 0.0 1.2e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-binding PF00249.31 OAG01349.1 - 0.031 14.5 0.0 11 6.3 0.0 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain Zn_clus PF00172.18 OAG01350.1 - 1.8e-05 24.7 18.0 3.1e-05 24.0 18.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.18 OAG01351.1 - 1.2e-25 90.1 0.0 1.9e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAG01351.1 - 0.031 15.0 0.0 0.08 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAG01351.1 - 0.15 12.8 0.0 0.32 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.13 OAG01352.1 - 3.3e-60 203.6 0.2 4.3e-60 203.2 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG01352.1 - 1.2e-18 67.7 0.4 1.7e-18 67.2 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG01352.1 - 0.0026 16.8 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG01352.1 - 0.0088 16.3 0.2 0.014 15.6 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OAG01352.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NOGCT PF08155.11 OAG01352.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 NOGCT (NUC087) domain MBOAT_2 PF13813.6 OAG01353.1 - 1.5e-20 73.3 3.1 2.1e-20 72.8 2.1 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Defensin_int PF17858.1 OAG01354.1 - 0.64 10.1 5.3 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide FAD_binding_4 PF01565.23 OAG01355.1 - 9.2e-30 103.2 3.4 2.9e-29 101.6 3.7 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG01355.1 - 3.4e-08 33.4 0.2 6.3e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M15_4 PF13539.6 OAG01355.1 - 0.069 13.7 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase ketoacyl-synt PF00109.26 OAG01356.1 - 2.2e-80 269.9 0.1 5.5e-80 268.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG01356.1 - 4.2e-49 167.8 4.3 4.3e-49 167.8 0.0 2.7 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG01356.1 - 1.9e-34 118.2 2.9 4.7e-34 116.9 2.9 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 OAG01356.1 - 2.9e-26 92.7 1.1 2.9e-26 92.7 1.1 2.6 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 OAG01356.1 - 6.2e-26 91.9 0.0 2.3e-25 90.1 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 OAG01356.1 - 1.5e-20 73.3 7.0 1.1e-09 38.5 0.7 2.9 3 0 0 3 3 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 OAG01356.1 - 1.3e-13 50.9 0.0 3.6e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 OAG01356.1 - 6.7e-07 30.1 1.7 9.2e-05 23.1 0.1 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 OAG01356.1 - 4e-05 23.1 0.1 0.00012 21.6 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.8 OAG01356.1 - 0.094 12.3 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) ACP_syn_III PF08545.10 OAG01356.1 - 0.38 10.6 1.9 0.89 9.4 0.4 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NACHT PF05729.12 OAG01357.1 - 1.2e-23 83.8 0.6 3.7e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain HET PF06985.11 OAG01357.1 - 3.7e-13 50.0 9.0 5.2e-11 43.1 1.1 3.3 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 OAG01357.1 - 0.0014 19.1 0.3 0.0052 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 OAG01357.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 OAG01357.1 - 0.16 12.4 0.0 1.4 9.3 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAG01357.1 - 0.19 11.5 0.0 0.64 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 OAG01358.1 - 4.1e-12 46.0 0.0 6.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG01358.1 - 3.4e-07 29.8 0.2 7e-07 28.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAG01358.1 - 0.0023 17.3 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG01358.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF2235 PF09994.9 OAG01359.1 - 4.4e-56 190.4 0.0 5.5e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BppU_IgG PF18667.1 OAG01359.1 - 0.012 15.7 0.1 0.032 14.4 0.1 1.7 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain Fe-ADH PF00465.19 OAG01364.1 - 1.4e-61 208.3 0.0 1.8e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG01364.1 - 5.4e-11 42.7 0.0 7.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DNA_pol3_a_NI PF14480.6 OAG01364.1 - 0.19 11.7 0.0 0.69 9.9 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I MTHFR PF02219.17 OAG01365.1 - 3.8e-114 380.8 0.0 5.8e-114 380.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TIM PF00121.18 OAG01366.1 - 6.4e-50 169.8 0.0 7.3e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ApoO PF09769.9 OAG01367.1 - 0.016 15.2 0.6 0.053 13.5 0.1 1.9 2 0 0 2 2 2 0 Apolipoprotein O NOG1_N PF17835.1 OAG01368.1 - 5.6e-49 166.2 1.1 7.6e-49 165.7 0.0 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 OAG01368.1 - 2.1e-26 91.6 3.1 5.5e-26 90.3 3.1 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 OAG01368.1 - 3.3e-25 87.6 0.1 6.6e-25 86.6 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 OAG01368.1 - 4e-14 52.7 0.0 1.2e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG01368.1 - 3.6e-06 26.6 0.0 9.5e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG01368.1 - 0.17 12.0 0.8 13 5.8 0.0 2.9 2 1 1 3 3 3 0 Dynamin family PAN_1 PF00024.26 OAG01369.1 - 1e-07 31.8 12.7 0.02 14.8 0.8 3.4 3 0 0 3 3 3 3 PAN domain SKG6 PF08693.10 OAG01369.1 - 0.093 12.2 0.4 0.22 11.0 0.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain E_raikovi_mat PF06360.11 OAG01369.1 - 4.9 7.7 11.4 3.8 8.0 0.5 3.4 3 0 0 3 3 3 0 Euplotes raikovi mating pheromone HeLo PF14479.6 OAG01370.1 - 0.016 15.0 7.0 0.021 14.6 4.6 1.9 1 1 1 2 2 2 0 Prion-inhibition and propagation DUF5486 PF17588.2 OAG01370.1 - 0.049 13.5 0.6 0.078 12.9 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5486) TMEM247 PF15444.6 OAG01370.1 - 0.36 10.9 3.2 0.49 10.4 3.2 1.4 1 1 0 1 1 1 0 Transmembrane protein 247 Spc24 PF08286.11 OAG01370.1 - 1.3 9.3 3.9 3.6 7.9 3.4 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tim17 PF02466.19 OAG01371.1 - 2.2e-28 98.9 3.6 2.9e-28 98.4 3.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pribosyltran PF00156.27 OAG01372.1 - 1.2e-17 63.9 0.3 1.9e-17 63.2 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG01372.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 OAG01373.1 - 7e-174 579.0 0.0 8.3e-174 578.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 OAG01373.1 - 0.072 12.6 0.1 4.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 zf-RanBP PF00641.18 OAG01374.1 - 0.00021 20.5 1.7 0.00021 20.5 1.7 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 OAG01374.1 - 0.19 11.8 5.9 0.076 13.0 1.5 2.2 2 0 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 OAG01374.1 - 1.9 8.4 9.6 0.3 11.0 0.8 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CHRD PF07452.12 OAG01375.1 - 1.2e-13 52.0 0.1 1.8e-13 51.5 0.1 1.2 1 0 0 1 1 1 1 CHRD domain Gpr1_Fun34_YaaH PF01184.19 OAG01376.1 - 4.2e-34 118.0 22.6 5.3e-34 117.6 22.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Bestrophin PF01062.21 OAG01380.1 - 1.3e-37 129.8 0.1 2.3e-37 129.0 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PHO4 PF01384.20 OAG01380.1 - 0.24 10.4 0.6 0.89 8.5 0.6 1.8 1 1 0 1 1 1 0 Phosphate transporter family Ank_2 PF12796.7 OAG01381.1 - 4.2e-11 43.3 2.6 0.021 15.4 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG01381.1 - 0.013 16.0 12.6 41 5.2 0.1 6.8 8 0 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 OAG01381.1 - 0.018 15.4 5.4 7.2 7.1 0.0 5.0 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG01381.1 - 0.025 15.2 6.5 27 5.5 0.1 5.7 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Porphobil_deamC PF03900.15 OAG01381.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Tautomerase_2 PF14552.6 OAG01381.1 - 0.18 11.9 0.1 4.5 7.4 0.0 3.0 3 0 0 3 3 3 0 Tautomerase enzyme SieB PF14163.6 OAG01382.1 - 0.075 12.5 2.4 0.21 11.1 2.4 1.8 1 0 0 1 1 1 0 Super-infection exclusion protein B p450 PF00067.22 OAG01383.1 - 2.4e-59 201.3 0.0 3.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2914 PF11141.8 OAG01386.1 - 0.07 12.9 0.0 0.92 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Fungal_trans PF04082.18 OAG01387.1 - 1.3e-20 73.6 0.6 2e-20 72.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01387.1 - 8.8e-06 25.8 7.5 1.6e-05 24.9 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 OAG01390.1 - 5.5e-70 236.6 0.2 6.9e-70 236.2 0.2 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 OAG01390.1 - 2.5e-37 128.7 0.0 4.3e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Transp_cyt_pur PF02133.15 OAG01391.1 - 4.2e-97 325.7 32.4 5.2e-97 325.4 32.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Adeno_E3B PF03376.14 OAG01391.1 - 0.71 10.1 3.4 1 9.6 0.2 2.6 3 0 0 3 3 3 0 Adenovirus E3B protein Fungal_trans_2 PF11951.8 OAG01392.1 - 2.8e-08 33.0 0.2 5e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01392.1 - 1.2e-07 31.8 10.2 2.6e-07 30.6 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIT PF01230.23 OAG01393.1 - 2.5e-24 85.9 1.5 2.6e-24 85.8 0.5 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 OAG01393.1 - 0.00019 21.9 0.1 0.00039 20.9 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 OAG01393.1 - 0.05 13.3 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain EF-hand_7 PF13499.6 OAG01395.1 - 1.1e-12 48.2 1.2 3.7e-07 30.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG01395.1 - 2e-12 46.0 2.1 0.00014 21.5 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OAG01395.1 - 2.5e-10 39.1 4.0 0.00082 18.8 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OAG01395.1 - 1.8e-09 37.8 0.0 0.00063 20.0 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OAG01395.1 - 0.00026 20.8 1.8 0.11 12.4 0.3 3.7 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OAG01395.1 - 0.00037 19.9 2.3 0.25 10.9 0.5 3.0 2 0 0 2 2 2 2 EF hand DUF166 PF02593.14 OAG01396.1 - 0.026 14.0 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Aspzincin_M35 PF14521.6 OAG01396.1 - 0.068 13.7 0.1 0.11 13.1 0.1 1.4 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase UPF0242 PF06785.11 OAG01397.1 - 0.025 14.7 5.8 0.024 14.8 5.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MetOD2 PF18548.1 OAG01397.1 - 0.054 13.6 2.9 0.063 13.4 2.9 1.3 1 1 0 1 1 1 0 Metanogen output domain 2 Fib_alpha PF08702.10 OAG01397.1 - 0.2 11.9 4.0 0.34 11.1 4.0 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OAG01397.1 - 0.68 10.6 10.2 1.2 9.8 10.2 1.5 1 1 0 1 1 1 0 SlyX peroxidase PF00141.23 OAG01399.1 - 9.2e-26 90.9 0.1 1.4e-25 90.4 0.1 1.2 1 0 0 1 1 1 1 Peroxidase CorA PF01544.18 OAG01400.1 - 6.7e-09 35.5 0.6 1.3e-08 34.6 0.6 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein adh_short PF00106.25 OAG01401.1 - 5.6e-09 35.7 0.6 6.2e-09 35.6 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 OAG01401.1 - 0.0023 17.4 0.1 0.0023 17.4 0.1 1.0 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.6 OAG01401.1 - 0.0027 17.3 0.4 0.0029 17.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HET PF06985.11 OAG01402.1 - 1.8e-25 90.0 0.2 2.6e-24 86.3 0.2 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_8 PF05148.15 OAG01403.1 - 1.7e-48 165.4 0.0 2.2e-25 89.8 0.0 3.3 4 0 0 4 4 4 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OAG01403.1 - 1.8e-05 25.3 0.0 5.6e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG01403.1 - 0.00018 22.1 0.0 0.0077 16.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG01403.1 - 0.0031 17.3 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.6 OAG01403.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain RTA1 PF04479.13 OAG01404.1 - 4.7e-73 245.2 4.5 5.9e-73 244.9 4.5 1.1 1 0 0 1 1 1 1 RTA1 like protein OPA3 PF07047.12 OAG01404.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Acetyltransf_10 PF13673.7 OAG01405.1 - 5.9e-08 32.7 0.0 8.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG01405.1 - 4.5e-07 30.1 0.0 6.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG01405.1 - 3.8e-06 27.2 0.0 5.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG01405.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OAG01405.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG01405.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cys_Met_Meta_PP PF01053.20 OAG01406.1 - 2.8e-139 463.9 0.0 3.3e-139 463.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG01406.1 - 3.8e-07 29.6 0.0 5.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAG01406.1 - 6.7e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 OAG01406.1 - 0.00013 20.6 0.0 0.00067 18.3 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 OAG01406.1 - 0.00042 19.7 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.13 OAG01406.1 - 0.0015 17.6 0.1 0.028 13.4 0.1 2.1 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase GDC-P PF02347.16 OAG01406.1 - 0.0086 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 OAG01406.1 - 0.025 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase TQ PF18202.1 OAG01406.1 - 0.041 14.4 0.0 0.12 12.9 0.1 1.7 2 0 0 2 2 2 0 T-Q ester bond containing domain DUF2415 PF10313.9 OAG01407.1 - 2.3e-15 56.2 0.0 4.8e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.12 OAG01407.1 - 0.0016 18.3 0.3 13 5.8 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat GlnD_UR_UTase PF08335.11 OAG01407.1 - 0.29 11.2 4.0 0.086 12.9 0.7 1.8 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase DASH_Spc19 PF08287.11 OAG01407.1 - 0.71 9.8 4.7 2.3 8.1 1.4 2.4 2 0 0 2 2 2 0 Spc19 HSP70 PF00012.20 OAG01408.1 - 5.7e-266 883.5 17.7 6.7e-266 883.2 17.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG01408.1 - 1.1e-13 50.7 5.3 1.7e-12 46.8 1.8 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 OAG01408.1 - 0.00018 21.3 0.1 0.00092 19.0 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Glyoxalase_4 PF13669.6 OAG01408.1 - 0.14 12.5 0.2 0.67 10.3 0.1 2.2 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SMBP PF16785.5 OAG01408.1 - 0.27 11.5 6.0 0.12 12.6 2.9 2.0 2 0 0 2 2 2 0 Small metal-binding protein DUF3213 PF11491.8 OAG01408.1 - 0.84 9.9 3.1 8.7 6.6 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3213) Fungal_trans_2 PF11951.8 OAG01410.1 - 6.5e-27 94.3 1.8 1.2e-26 93.4 1.8 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01410.1 - 2.9e-09 36.9 6.4 2.9e-09 36.9 6.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4215 PF13948.6 OAG01410.1 - 6.1 7.4 6.7 13 6.3 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) Ribonuc_L-PSP PF01042.21 OAG01411.1 - 8.8e-20 70.9 0.0 1e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjbT PF17089.5 OAG01411.1 - 0.029 14.4 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family DUF3445 PF11927.8 OAG01412.1 - 1.1e-77 260.6 0.2 1.4e-77 260.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) AA_permease_2 PF13520.6 OAG01413.1 - 3.4e-44 151.4 54.7 4.1e-44 151.1 54.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG01413.1 - 4.4e-19 68.4 44.4 5.7e-19 68.1 44.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC3A2_N PF16028.5 OAG01413.1 - 5.7 6.6 8.9 3.3 7.3 0.3 3.5 2 1 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Aldedh PF00171.22 OAG01414.1 - 7.7e-181 601.6 0.4 8.7e-181 601.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PALP PF00291.25 OAG01417.1 - 8.8e-67 225.6 0.3 1.1e-66 225.3 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 OAG01417.1 - 2e-11 44.2 0.0 2.6e-07 31.0 0.0 3.5 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.10 OAG01418.1 - 7.5e-30 103.7 0.0 4.2e-29 101.2 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OAG01418.1 - 3.4e-06 26.6 0.0 2.4e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG01418.1 - 0.00035 20.6 0.0 0.00082 19.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG01418.1 - 0.00081 19.0 0.0 0.0048 16.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OAG01418.1 - 0.001 19.5 0.1 0.0034 17.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 OAG01418.1 - 0.0042 16.5 0.0 0.017 14.5 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 OAG01418.1 - 0.02 14.5 0.1 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain BatA PF07584.11 OAG01418.1 - 0.023 15.1 0.3 0.054 13.9 0.3 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal AAA PF00004.29 OAG01418.1 - 0.035 14.5 0.1 0.19 12.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 OAG01418.1 - 0.048 13.3 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 OAG01418.1 - 0.093 13.0 0.1 0.18 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG01418.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 OAG01418.1 - 0.1 12.8 0.0 0.56 10.4 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAG01418.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 OAG01418.1 - 0.22 11.3 0.0 6.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NDT80_PhoG PF05224.12 OAG01420.1 - 1e-36 126.9 0.0 2e-36 125.9 0.0 1.5 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Paramyxo_C PF01692.18 OAG01422.1 - 0.19 11.1 0.2 0.24 10.7 0.2 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C Peptidase_M78 PF06114.13 OAG01425.1 - 0.099 12.6 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 IrrE N-terminal-like domain SnoaL_2 PF12680.7 OAG01426.1 - 0.013 16.1 0.0 0.02 15.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Cellulase PF00150.18 OAG01427.1 - 5.5e-20 71.9 4.2 1.4e-19 70.6 4.2 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amidase_3 PF01520.18 OAG01427.1 - 0.13 12.4 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase DUF1772 PF08592.11 OAG01428.1 - 5.4e-23 81.8 0.4 6.7e-23 81.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) NmrA PF05368.13 OAG01429.1 - 7.2e-33 114.1 0.0 1.1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG01429.1 - 9.1e-14 51.8 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG01429.1 - 0.00045 19.8 0.0 0.0015 18.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG01429.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.4 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 OAG01429.1 - 0.057 12.5 0.2 0.31 10.1 0.2 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG01429.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SnoaL PF07366.12 OAG01430.1 - 0.056 13.2 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase FAD_binding_3 PF01494.19 OAG01431.1 - 6.2e-15 55.3 3.8 1.2e-12 47.7 3.8 3.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG01431.1 - 1e-09 38.1 0.1 0.00077 18.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG01431.1 - 1.6e-08 34.5 1.7 0.0034 17.0 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG01431.1 - 9.2e-08 31.6 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG01431.1 - 1.6e-06 27.1 0.1 0.0022 16.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 OAG01431.1 - 2.3e-05 23.8 0.1 0.0011 18.3 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG01431.1 - 7.2e-05 22.9 0.1 0.00019 21.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG01431.1 - 8e-05 22.2 0.2 0.0002 20.9 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG01431.1 - 0.00015 21.0 0.1 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG01431.1 - 0.00015 21.0 0.2 0.17 10.9 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAG01431.1 - 0.0016 17.7 0.0 0.0051 16.1 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OAG01431.1 - 0.0041 16.5 0.2 0.8 8.9 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG01431.1 - 0.0044 17.6 0.1 0.09 13.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG01431.1 - 0.025 14.6 0.8 0.48 10.4 0.8 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG01431.1 - 0.056 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 OAG01431.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 OAG01433.1 - 1.3e-56 192.3 0.0 2.4e-56 191.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF2418 PF10332.9 OAG01437.1 - 1.2e-32 112.3 0.2 2.3e-32 111.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 OAG01438.1 - 2.6e-32 111.0 0.1 3e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 OAG01439.1 - 1.2e-28 100.2 0.3 1.5e-28 99.9 0.3 1.1 1 0 0 1 1 1 1 ML domain CopC PF04234.12 OAG01439.1 - 0.063 14.3 0.0 0.14 13.2 0.0 1.6 1 1 0 1 1 1 0 CopC domain DUF4625 PF15418.6 OAG01439.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) DUF4832 PF16116.5 OAG01439.1 - 0.15 11.9 0.1 2.4 8.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4832) Erythro-docking PF09277.11 OAG01440.1 - 0.019 14.9 1.0 0.62 10.0 0.2 2.5 2 0 0 2 2 2 0 Erythronolide synthase, docking bZIP_1 PF00170.21 OAG01440.1 - 0.2 11.7 1.5 28 4.9 0.1 2.9 3 0 0 3 3 3 0 bZIP transcription factor SlyX PF04102.12 OAG01440.1 - 0.84 10.3 5.3 4.4 8.0 0.3 3.2 3 1 0 3 3 3 0 SlyX Syntaxin-6_N PF09177.11 OAG01440.1 - 3.3 8.3 6.3 0.32 11.6 0.7 2.3 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Chitin_synth_1 PF01644.17 OAG01441.1 - 7.4e-79 263.4 0.1 1.2e-78 262.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAG01441.1 - 1.8e-27 95.1 0.2 5.1e-27 93.6 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG01441.1 - 7e-22 77.7 0.6 2.2e-19 69.5 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG01441.1 - 2.8e-06 27.4 3.9 2.8e-06 27.4 3.9 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG01441.1 - 0.097 12.5 0.0 0.65 9.8 0.0 2.1 1 1 1 2 2 2 0 Glycosyltransferase like family 2 CitMHS PF03600.16 OAG01441.1 - 0.2 10.8 1.5 0.31 10.2 1.5 1.3 1 0 0 1 1 1 0 Citrate transporter MR_MLE_C PF13378.6 OAG01444.1 - 7e-58 195.8 0.0 1.1e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAG01444.1 - 3.8e-05 23.9 0.2 0.00011 22.4 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 OAG01444.1 - 6.9e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus PWI PF01480.17 OAG01445.1 - 4.2e-14 52.6 2.0 2.6e-13 50.1 0.2 2.7 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 OAG01445.1 - 0.00028 20.6 0.0 0.00075 19.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S21 PF01165.20 OAG01446.1 - 3.3e-12 45.9 1.1 6.1e-12 45.1 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 PGI PF00342.19 OAG01448.1 - 1.9e-242 805.1 0.9 2.2e-242 804.9 0.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 OAG01449.1 - 2.6e-69 233.5 0.0 3.2e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG01449.1 - 1e-33 116.7 0.0 1.4e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAG01449.1 - 3.3e-10 40.5 0.3 1.2e-09 38.7 0.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAG01449.1 - 4.6e-06 25.8 0.0 6.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAG01449.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 OAG01449.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 C2 domain Myb_DNA-binding PF00249.31 OAG01450.1 - 2e-09 37.5 0.0 6.4e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 OAG01450.1 - 1.5e-06 28.5 0.1 6.2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.17 OAG01450.1 - 6.7e-05 22.6 4.9 0.00013 21.7 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Ank_2 PF12796.7 OAG01453.1 - 1.1e-10 41.9 2.9 2.6e-07 31.1 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG01453.1 - 5.4e-07 30.0 0.1 0.00028 21.4 0.0 3.0 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG01453.1 - 1.2e-06 28.6 0.7 0.17 12.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OAG01453.1 - 5.7e-06 26.3 0.7 4.7 8.1 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OAG01453.1 - 6.7e-05 23.1 2.4 0.00093 19.5 0.4 2.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) UPF0147 PF03685.13 OAG01454.1 - 0.12 12.4 1.7 0.97 9.5 0.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0147) DNA_pol3_delta PF06144.13 OAG01454.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF4404 PF14357.6 OAG01454.1 - 0.15 12.7 0.1 0.29 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) HET PF06985.11 OAG01455.1 - 2.9e-13 50.4 6.6 6.3e-11 42.8 1.1 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 OAG01455.1 - 2.9e-12 46.8 0.9 4.7e-12 46.1 0.2 1.7 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 OAG01455.1 - 1.2e-09 38.7 0.1 1.1e-07 32.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG01455.1 - 5.4e-07 29.4 0.2 0.22 12.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OAG01455.1 - 1.4e-06 28.5 0.6 0.18 12.3 0.0 3.7 4 0 0 4 4 3 2 Ankyrin repeat Ank_4 PF13637.6 OAG01455.1 - 9.8e-06 26.0 0.0 0.00023 21.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RNA_helicase PF00910.22 OAG01455.1 - 0.00088 19.6 1.8 0.0019 18.6 0.0 2.6 3 1 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 OAG01455.1 - 0.01 16.2 0.0 0.039 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Ank_5 PF13857.6 OAG01455.1 - 0.019 15.3 0.1 1.9 8.9 0.1 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) AAA PF00004.29 OAG01455.1 - 0.02 15.3 0.0 0.064 13.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAG01455.1 - 0.031 14.3 0.0 0.17 11.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain Ank_4 PF13637.6 OAG01456.1 - 1.9e-16 60.2 0.0 2.4e-08 34.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG01456.1 - 1.2e-11 45.0 0.0 1.4e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG01456.1 - 1.9e-11 43.8 0.1 0.00035 20.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OAG01456.1 - 5e-07 29.5 0.0 0.31 11.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG01456.1 - 0.00025 21.3 0.1 0.043 14.1 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF1972 PF09314.11 OAG01456.1 - 0.088 12.4 0.0 7.5 6.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1972) Patatin PF01734.22 OAG01457.1 - 2.1e-17 64.0 1.3 5e-17 62.7 1.3 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase AFG1_ATPase PF03969.16 OAG01458.1 - 3.5e-93 312.4 0.0 1.3e-88 297.3 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OAG01458.1 - 0.00093 19.6 0.0 0.82 10.0 0.0 3.6 3 1 1 4 4 4 1 AAA ATPase domain Bac_DnaA PF00308.18 OAG01458.1 - 0.0034 17.2 0.2 1.8 8.4 0.0 2.7 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 OAG01458.1 - 0.0041 17.2 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG01458.1 - 0.023 15.0 0.0 0.23 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG01458.1 - 0.096 12.2 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 OAG01458.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI eIF3g PF12353.8 OAG01459.1 - 2.8e-42 144.1 6.9 4.1e-42 143.5 6.9 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OAG01459.1 - 2.9e-18 65.5 0.0 5.1e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG01459.1 - 0.041 13.7 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_5 PF13893.6 OAG01459.1 - 0.085 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAG01459.1 - 0.2 11.7 3.4 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif NmrA PF05368.13 OAG01460.1 - 5.7e-38 130.8 0.2 7.2e-38 130.4 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG01460.1 - 4.8e-11 42.9 0.1 6.5e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG01460.1 - 1.9e-08 34.1 0.0 4.6e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG01460.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG01460.1 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAG01460.1 - 0.0023 17.4 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 OAG01460.1 - 0.0024 16.9 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 OAG01460.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus T3SS_HrpK1 PF16937.5 OAG01460.1 - 0.013 15.1 0.0 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Type III secretion system translocator protein, HrpF DUF3553 PF12073.8 OAG01460.1 - 0.021 14.5 0.4 0.045 13.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) SAM_3 PF18016.1 OAG01460.1 - 0.036 13.9 0.1 0.088 12.6 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RmlD_sub_bind PF04321.17 OAG01460.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DHHC PF01529.20 OAG01461.1 - 4.1e-35 120.8 7.5 4.1e-35 120.8 7.5 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 OAG01461.1 - 4.9e-25 87.9 0.9 8.2e-11 42.3 0.4 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG01461.1 - 3.2e-23 81.8 3.8 5.8e-07 29.9 0.3 4.8 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG01461.1 - 1.1e-22 79.7 2.7 1.5e-07 31.5 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG01461.1 - 3.1e-22 78.0 3.0 3.4e-06 27.2 0.4 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OAG01461.1 - 1.6e-16 58.7 8.8 5.1e-07 29.5 0.4 6.3 7 0 0 7 7 7 4 Ankyrin repeat YfhO PF09586.10 OAG01461.1 - 0.046 12.0 4.7 0.069 11.4 4.7 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF5337 PF17272.2 OAG01461.1 - 0.24 11.2 3.5 0.15 11.9 0.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5337) LANC_like PF05147.13 OAG01462.1 - 2.4e-22 79.0 0.1 8.7e-19 67.3 0.4 2.7 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein Tyrosinase PF00264.20 OAG01463.1 - 2.4e-34 119.6 1.2 3.7e-34 119.0 1.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DEAD PF00270.29 OAG01464.1 - 1e-28 100.3 0.0 2e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OAG01464.1 - 1.7e-20 73.6 0.9 6.3e-20 71.7 0.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OAG01464.1 - 9.1e-13 48.5 0.0 2.8e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.11 OAG01464.1 - 1.6e-07 31.8 0.2 3.5e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 OAG01464.1 - 1.4e-06 28.4 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit adh_short PF00106.25 OAG01465.1 - 3.8e-15 55.9 0.0 4.3e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01465.1 - 3.5e-08 33.3 0.0 4.2e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG01465.1 - 3.6e-08 33.5 0.0 4.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 OAG01466.1 - 8e-14 51.7 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG01466.1 - 1.7e-11 44.3 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG01466.1 - 1.8e-08 34.2 0.1 6.1e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAG01466.1 - 0.00033 20.9 0.1 0.00058 20.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.17 OAG01466.1 - 0.018 14.2 0.5 0.025 13.7 0.1 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 OAG01466.1 - 0.033 14.6 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LpxI_N PF17930.1 OAG01466.1 - 0.065 13.1 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 LpxI N-terminal domain KR PF08659.10 OAG01466.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 KR domain PrpF PF04303.13 OAG01467.1 - 8e-108 360.7 2.9 9.1e-108 360.5 2.9 1.0 1 0 0 1 1 1 1 PrpF protein GFO_IDH_MocA PF01408.22 OAG01468.1 - 1.4e-14 54.9 0.0 2.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG01468.1 - 0.081 13.6 0.0 0.64 10.7 0.0 2.3 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain HET PF06985.11 OAG01469.1 - 2.1e-32 112.5 0.9 2.4e-32 112.3 0.9 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PDEase_II PF02112.15 OAG01471.1 - 1e-48 166.2 0.0 7e-23 81.3 0.0 3.3 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II EF1G PF00647.19 OAG01471.1 - 1.1e-43 147.6 0.5 2.2e-43 146.7 0.5 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 OAG01471.1 - 4.6e-12 46.1 0.0 1.9e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG01471.1 - 3.8e-10 39.9 0.1 1.2e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG01471.1 - 6.2e-08 32.6 0.1 2.7e-07 30.5 0.1 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG01471.1 - 1.4e-07 31.8 0.0 3.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG01471.1 - 0.0012 19.0 0.1 0.0031 17.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG01471.1 - 0.0061 16.8 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lactamase_B PF00753.27 OAG01471.1 - 0.016 15.3 1.2 0.27 11.2 0.4 2.8 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily Ribosomal_S9 PF00380.19 OAG01472.1 - 7.4e-42 142.7 0.2 1.2e-41 142.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BAR_2 PF10455.9 OAG01474.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking MatE PF01554.18 OAG01475.1 - 9.2e-61 204.2 33.7 1.8e-37 128.5 9.5 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OAG01475.1 - 0.00017 21.7 14.2 0.00017 21.7 14.2 4.4 4 1 1 5 5 5 1 Polysaccharide biosynthesis C-terminal domain GST_N_2 PF13409.6 OAG01476.1 - 6.6e-09 35.9 0.1 1.1e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG01476.1 - 3.9e-08 33.6 0.1 9.8e-08 32.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG01476.1 - 2.1e-05 24.5 0.1 4.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG01476.1 - 0.021 15.2 0.0 0.047 14.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 OAG01478.1 - 3.6e-15 55.7 50.4 6.6e-08 31.9 20.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ORC4_C PF14629.6 OAG01479.1 - 3.3e-53 180.3 0.0 4.8e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 OAG01479.1 - 1.1e-15 58.4 0.2 3.8e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG01479.1 - 3.9e-07 30.4 0.0 9.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAG01479.1 - 6.2e-05 22.3 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 OAG01479.1 - 8.7e-05 23.0 0.0 0.00021 21.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG01479.1 - 0.0005 20.0 0.2 0.008 16.1 0.2 2.3 1 1 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 OAG01479.1 - 0.0065 16.2 0.2 0.13 12.0 0.1 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain KAP_NTPase PF07693.14 OAG01479.1 - 0.0081 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain ATPase_2 PF01637.18 OAG01479.1 - 0.0093 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OAG01479.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 OAG01479.1 - 0.022 13.9 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 OAG01479.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 OAG01479.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 OAG01479.1 - 0.11 11.9 0.1 1.7 8.0 0.1 2.3 1 1 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 OAG01479.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.9 OAG01479.1 - 0.16 10.9 0.2 3 6.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PBP1_TM PF14812.6 OAG01479.1 - 6.7 7.2 8.3 1.5 9.3 3.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal adh_short PF00106.25 OAG01480.1 - 6.2e-84 280.3 7.6 3.2e-44 150.7 1.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01480.1 - 3.8e-66 223.0 2.8 7.3e-35 120.6 0.2 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OAG01480.1 - 1.2e-33 115.2 0.0 2.4e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 OAG01480.1 - 5.7e-28 98.0 2.3 3.5e-14 53.1 0.2 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 OAG01480.1 - 0.0018 18.4 0.0 0.37 10.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 OAG01480.1 - 0.0018 17.6 0.9 0.16 11.2 0.1 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG01480.1 - 0.25 10.8 2.2 0.57 9.6 0.1 2.5 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG01480.1 - 3.6 7.4 6.3 21 5.0 0.5 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 OAG01481.1 - 1.1e-12 48.1 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG01481.1 - 5.5e-08 33.4 0.0 1.5e-07 32.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG01481.1 - 2e-07 31.6 0.0 3.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG01481.1 - 7.2e-07 29.8 0.0 1.3e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG01481.1 - 2e-06 27.7 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG01481.1 - 0.084 12.3 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.20 OAG01481.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Lipase_GDSL PF00657.22 OAG01482.1 - 3.8e-10 40.1 0.1 5.2e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAG01482.1 - 0.00028 21.3 1.1 0.00056 20.4 0.5 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family H2TH PF06831.14 OAG01482.1 - 0.13 12.3 0.0 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain Alk_phosphatase PF00245.20 OAG01483.1 - 2e-81 274.1 0.8 2.5e-81 273.8 0.8 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OAG01483.1 - 0.011 15.2 0.0 0.034 13.5 0.0 1.9 1 1 0 1 1 1 0 Metalloenzyme superfamily Abhydrolase_2 PF02230.16 OAG01484.1 - 1.6e-14 54.2 0.1 2.9e-09 37.1 0.0 2.9 2 1 2 4 4 4 2 Phospholipase/Carboxylesterase BTB PF00651.31 OAG01485.1 - 1.6e-05 25.1 0.0 0.00038 20.6 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain NAGLU PF05089.12 OAG01486.1 - 2.1e-131 437.9 6.7 2.1e-131 437.9 6.7 1.8 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OAG01486.1 - 8e-65 219.0 0.8 1.2e-64 218.4 0.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OAG01486.1 - 4.9e-17 61.5 0.0 1e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Cyclin PF08613.11 OAG01487.1 - 2.1e-24 86.7 0.0 2.8e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin KRE9 PF05390.11 OAG01488.1 - 8.5e-17 61.8 8.6 8.5e-17 61.8 8.6 2.0 1 1 1 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 OAG01488.1 - 2.2e-11 44.4 0.3 2.2e-11 44.4 0.3 2.2 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAR2 PF16974.5 OAG01488.1 - 0.0065 15.9 0.1 4.4 6.7 0.0 2.5 2 0 0 2 2 2 2 High-affinity nitrate transporter accessory Sugar_tr PF00083.24 OAG01489.1 - 2e-65 221.4 19.4 2.3e-65 221.2 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01489.1 - 1.8e-21 76.4 33.1 1.3e-16 60.5 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG01490.1 - 8.2e-26 90.6 0.1 1.4e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAG01491.1 - 2.1e-82 277.4 22.0 2.5e-82 277.1 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01491.1 - 3.5e-21 75.5 46.2 1.4e-14 53.8 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Vac14_Fab1_bd PF12755.7 OAG01491.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Amidohydro_2 PF04909.14 OAG01492.1 - 1e-22 81.3 0.0 1.2e-22 81.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Acetyltransf_1 PF00583.25 OAG01493.1 - 2.1e-14 53.8 0.0 2.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG01493.1 - 3.4e-08 33.8 0.0 5.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG01493.1 - 3.1e-07 30.4 0.0 4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG01493.1 - 1.4e-05 25.1 0.0 9.8e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG01493.1 - 5.7e-05 23.0 0.0 0.00012 22.0 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 OAG01493.1 - 0.0043 17.7 0.0 0.0055 17.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG01493.1 - 0.023 14.9 0.0 0.028 14.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG01493.1 - 0.026 14.6 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidase PF01425.21 OAG01494.1 - 6.5e-102 341.8 0.0 7.8e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 Amidase NAD_binding_10 PF13460.6 OAG01495.1 - 1e-06 28.8 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG01495.1 - 0.00026 20.5 0.0 0.00038 20.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG01495.1 - 0.0069 15.4 0.0 0.0083 15.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG01495.1 - 0.021 14.0 0.0 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein AAA_2 PF07724.14 OAG01496.1 - 7.1e-47 159.7 0.0 4e-45 154.0 0.0 3.2 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAG01496.1 - 8.8e-35 118.8 1.3 8.8e-35 118.8 1.3 4.2 4 1 0 4 4 4 1 AAA lid domain AAA PF00004.29 OAG01496.1 - 1.5e-26 93.4 0.0 6.1e-14 52.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAG01496.1 - 4.1e-24 84.4 1.6 6.9e-24 83.7 0.3 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAG01496.1 - 9.2e-16 58.1 0.3 7.7e-10 38.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG01496.1 - 3.9e-13 49.8 0.0 2.7e-05 24.5 0.0 4.1 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 OAG01496.1 - 8.5e-10 39.3 14.6 7.2e-06 26.5 0.1 5.6 4 3 1 6 6 4 2 AAA ATPase domain Clp_N PF02861.20 OAG01496.1 - 3.4e-09 36.7 0.1 0.0068 16.5 0.0 4.0 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 OAG01496.1 - 6.3e-09 35.8 0.0 2e-05 24.4 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 OAG01496.1 - 3.5e-06 26.7 0.0 0.013 15.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 OAG01496.1 - 7.2e-06 26.1 0.0 0.11 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAG01496.1 - 7.3e-06 25.8 0.0 0.089 12.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 OAG01496.1 - 9.9e-06 25.8 0.1 0.28 11.4 0.0 3.5 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OAG01496.1 - 1.4e-05 24.6 0.1 0.21 11.0 0.0 3.4 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAG01496.1 - 1.5e-05 25.5 4.7 0.12 12.9 0.0 4.8 5 1 0 5 5 4 2 AAA domain AAA_30 PF13604.6 OAG01496.1 - 3.1e-05 23.8 0.0 0.32 10.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAG01496.1 - 3.9e-05 24.0 0.4 0.73 10.1 0.0 3.8 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 OAG01496.1 - 6.2e-05 23.3 0.0 0.5 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 OAG01496.1 - 0.00012 22.1 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OAG01496.1 - 0.00015 21.6 0.0 0.79 9.6 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAG01496.1 - 0.00031 20.7 0.1 0.46 10.4 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_19 PF13245.6 OAG01496.1 - 0.00032 21.0 0.2 0.23 11.8 0.3 3.8 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OAG01496.1 - 0.00062 19.5 0.0 0.64 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG01496.1 - 0.00066 20.2 1.6 0.67 10.5 0.0 3.4 4 0 0 4 4 3 1 ABC transporter ATPase_2 PF01637.18 OAG01496.1 - 0.00087 19.3 2.3 4.9 7.0 0.1 4.3 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 OAG01496.1 - 0.0013 18.5 2.2 4.6 7.0 0.9 4.3 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 OAG01496.1 - 0.0016 17.6 0.0 0.016 14.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 OAG01496.1 - 0.002 17.9 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OAG01496.1 - 0.0044 16.6 0.4 0.69 9.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAG01496.1 - 0.005 16.2 0.0 0.62 9.3 0.0 3.0 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 OAG01496.1 - 0.0056 16.6 0.0 0.58 10.0 0.0 3.0 3 0 0 3 3 2 1 NACHT domain Roc PF08477.13 OAG01496.1 - 0.0078 16.4 0.0 3 8.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 OAG01496.1 - 0.008 16.1 0.0 0.27 11.1 0.0 3.0 3 0 0 3 3 2 1 NTPase DUF1192 PF06698.11 OAG01496.1 - 0.0098 15.9 0.4 0.0098 15.9 0.4 3.2 1 1 2 3 3 1 1 Protein of unknown function (DUF1192) SRP54 PF00448.22 OAG01496.1 - 0.012 15.2 0.0 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 OAG01496.1 - 0.026 14.4 0.0 8.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Torsin PF06309.11 OAG01496.1 - 0.031 14.4 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 1 0 Torsin ResIII PF04851.15 OAG01496.1 - 0.033 14.2 0.0 3.4 7.6 0.0 3.7 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit CbiA PF01656.23 OAG01496.1 - 0.069 13.2 0.0 9.7 6.3 0.0 3.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain V_ATPase_I PF01496.19 OAG01496.1 - 0.14 10.1 4.1 0.22 9.4 4.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP_bind_1 PF03029.17 OAG01496.1 - 0.15 11.9 0.0 20 4.9 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 OAG01496.1 - 0.21 11.4 0.4 14 5.3 0.0 3.5 4 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 OAG01496.1 - 0.28 10.0 16.4 0.66 8.8 16.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Sigma70_r1_1 PF03979.14 OAG01496.1 - 0.4 10.8 9.2 4.2 7.5 1.2 3.7 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 AAA_23 PF13476.6 OAG01496.1 - 0.41 11.1 0.0 0.41 11.1 0.0 4.8 4 2 0 4 4 2 0 AAA domain CorA PF01544.18 OAG01496.1 - 0.48 9.7 5.8 1.3 8.3 5.8 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TMF_TATA_bd PF12325.8 OAG01496.1 - 1.3 9.2 21.4 0.31 11.3 12.2 3.2 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.8 OAG01496.1 - 1.4 9.1 5.2 2.8 8.1 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) CLZ PF16526.5 OAG01496.1 - 4.2 7.8 11.3 1.5 9.3 3.0 3.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BRE1 PF08647.11 OAG01496.1 - 8.8 6.5 26.8 0.6 10.2 1.3 3.3 3 1 1 4 4 2 0 BRE1 E3 ubiquitin ligase Peptidase_C12 PF01088.21 OAG01499.1 - 5.7e-66 222.3 0.0 1.1e-65 221.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 OAG01499.1 - 4.3e-11 42.5 0.0 4.3e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases YodL PF14191.6 OAG01499.1 - 0.03 15.2 0.0 0.13 13.1 0.0 2.0 2 1 0 2 2 2 0 YodL-like Pyr_redox_2 PF07992.14 OAG01500.1 - 4.2e-43 147.7 0.0 4.9e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG01500.1 - 1.4e-09 38.4 0.2 2.3e-06 28.1 0.3 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG01500.1 - 0.0017 18.6 0.2 0.06 13.6 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG01500.1 - 0.0031 16.6 2.0 1.1 8.2 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 OAG01500.1 - 0.018 14.7 6.1 0.97 8.9 0.0 3.2 2 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAG01500.1 - 0.066 13.7 0.0 7 7.1 0.0 2.7 1 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAG01500.1 - 0.075 12.3 0.2 9.9 5.3 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG01500.1 - 0.2 11.3 0.2 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.18 OAG01501.1 - 1.3e-08 34.8 12.6 1.9e-08 34.3 12.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG01501.1 - 0.00011 21.2 2.5 0.00017 20.5 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_EZ PF13513.6 OAG01503.1 - 4.9e-27 94.0 14.5 7.8e-13 48.6 0.0 9.9 9 1 0 10 10 10 5 HEAT-like repeat HEAT PF02985.22 OAG01503.1 - 4.8e-24 82.4 9.6 3.6e-05 23.6 0.0 10.0 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 OAG01503.1 - 5.1e-17 62.1 0.1 0.037 14.4 0.1 7.0 5 1 0 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 OAG01503.1 - 3.3e-10 40.4 0.0 0.039 14.5 0.0 6.0 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAG01503.1 - 5.8e-10 39.4 0.0 0.081 13.0 0.0 5.5 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 OAG01503.1 - 2.2e-08 33.9 0.0 6.6e-07 29.2 0.0 3.3 3 1 0 3 3 2 1 Importin-beta N-terminal domain MMS19_C PF12460.8 OAG01503.1 - 1.3e-05 24.6 1.3 0.44 9.6 0.1 5.2 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal Arm PF00514.23 OAG01503.1 - 0.00069 19.6 1.8 7.2 6.8 0.0 6.2 8 0 0 8 8 7 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 OAG01503.1 - 0.0056 16.3 0.0 31 4.0 0.0 5.1 7 0 0 7 7 7 0 CLASP N terminal Telomere_reg-2 PF10193.9 OAG01503.1 - 0.0077 16.7 0.2 0.37 11.2 0.0 3.6 4 0 0 4 4 4 1 Telomere length regulation protein TAF6_C PF07571.13 OAG01503.1 - 0.016 15.5 0.0 9.1 6.7 0.0 3.6 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Adaptin_N PF01602.20 OAG01503.1 - 0.035 12.7 0.0 8.1 4.9 0.0 3.5 4 0 0 4 4 4 0 Adaptin N terminal region CRM1_repeat_3 PF18787.1 OAG01503.1 - 0.12 12.5 0.0 19 5.4 0.0 3.1 2 0 0 2 2 2 0 CRM1 / Exportin repeat 3 SSDP PF04503.13 OAG01503.1 - 0.15 12.3 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP HEAT_PBS PF03130.16 OAG01503.1 - 0.18 12.5 5.9 33 5.6 0.0 5.4 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat RNR_inhib PF08591.10 OAG01506.1 - 2.7e-26 93.0 0.1 6.7e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF2976 PF11190.8 OAG01507.1 - 0.007 16.1 0.1 4.8 7.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2976) MARVEL PF01284.23 OAG01507.1 - 0.068 13.2 7.6 0.13 12.3 7.6 1.4 1 1 0 1 1 1 0 Membrane-associating domain BPD_transp_1 PF00528.22 OAG01507.1 - 0.55 9.9 7.9 0.14 11.9 3.5 2.1 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component PET117 PF15786.5 OAG01507.1 - 0.85 9.9 0.1 0.85 9.9 0.1 3.2 4 1 0 4 4 4 0 PET assembly of cytochrome c oxidase, mitochondrial 2TM PF13239.6 OAG01507.1 - 0.95 9.8 3.4 8.5 6.8 0.3 2.6 2 2 0 2 2 2 0 2TM domain TMEM239 PF15841.5 OAG01507.1 - 0.95 9.4 9.9 0.081 12.8 4.9 1.8 2 1 0 2 2 2 0 Transmembrane protein 239 family LysM PF01476.20 OAG01509.1 - 0.004 17.2 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain Prok-RING_4 PF14447.6 OAG01509.1 - 0.084 12.7 8.6 0.15 11.9 8.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 OAG01509.1 - 0.19 11.7 2.7 0.34 10.9 2.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Ribosomal_S8 PF00410.19 OAG01510.1 - 1.4e-21 76.8 0.2 2e-21 76.2 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 N2227 PF07942.12 OAG01511.1 - 2.5e-92 308.9 0.0 3e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 OAG01511.1 - 0.0002 22.0 0.0 0.00052 20.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG01511.1 - 0.0004 20.2 0.0 0.0008 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG01511.1 - 0.018 15.7 0.0 0.24 12.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain PAC4 PF16093.5 OAG01512.1 - 8.5e-23 80.4 0.0 1.2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Con-6 PF10346.9 OAG01513.1 - 1.4e-30 105.0 6.9 1.6e-15 56.8 0.5 2.2 2 0 0 2 2 2 2 Conidiation protein 6 DUF1542 PF07564.11 OAG01513.1 - 0.0058 16.7 0.6 1.3 9.2 0.2 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1542) SpoIIIAH PF12685.7 OAG01513.1 - 0.15 11.9 4.6 0.41 10.5 0.4 2.1 1 1 0 2 2 2 0 SpoIIIAH-like protein ADH_zinc_N PF00107.26 OAG01514.1 - 3.4e-14 52.9 0.0 5.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG01514.1 - 2.2e-08 34.0 0.9 5.1e-08 32.8 0.1 2.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG01514.1 - 2.7e-08 35.0 0.1 1.4e-07 32.6 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 OAG01514.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 OAG01514.1 - 0.0054 16.1 0.8 0.0092 15.3 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HTH_Tnp_ISL3 PF13542.6 OAG01514.1 - 0.029 13.8 0.1 0.075 12.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ADH_N_2 PF16884.5 OAG01514.1 - 0.096 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ATG27 PF09451.10 OAG01517.1 - 2e-81 273.7 0.0 2.4e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 DUF1774 PF08611.10 OAG01518.1 - 5.5e-31 106.7 0.1 5.5e-31 106.7 0.1 2.6 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) T_cell_tran_alt PF15128.6 OAG01518.1 - 2.8 7.8 4.9 3.4 7.5 0.1 2.8 2 1 1 3 3 3 0 T-cell leukemia translocation-altered Adaptin_N PF01602.20 OAG01519.1 - 5.5e-123 411.3 12.4 6.8e-123 411.0 12.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG01519.1 - 3.1e-58 196.4 2.3 3.1e-58 196.4 2.3 3.2 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG01519.1 - 1.3e-13 51.2 4.6 9.2e-08 32.4 0.1 5.0 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 OAG01519.1 - 3.2e-12 45.6 3.7 0.0011 19.0 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 OAG01519.1 - 3.3e-05 24.3 1.1 0.34 11.5 0.0 5.3 4 1 1 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 OAG01519.1 - 0.00035 20.2 2.8 0.059 12.9 0.1 3.8 3 1 0 3 3 3 1 CLASP N terminal Arm PF00514.23 OAG01519.1 - 0.0026 17.7 3.4 1.2 9.2 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat T_hemolysin PF12261.8 OAG01519.1 - 0.0041 16.9 0.2 0.27 11.0 0.0 2.4 2 0 0 2 2 2 1 Thermostable hemolysin Nipped-B_C PF12830.7 OAG01519.1 - 0.007 16.3 0.7 2.3 8.1 0.0 3.3 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus RTP1_C1 PF10363.9 OAG01519.1 - 0.02 15.0 4.1 2.6 8.3 0.1 3.6 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF2496 PF10689.9 OAG01519.1 - 0.021 14.6 0.1 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) SHE3 PF17078.5 OAG01519.1 - 0.11 12.2 0.3 0.35 10.5 0.0 2.0 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 ENTH PF01417.20 OAG01519.1 - 0.16 12.0 0.5 0.63 10.1 0.1 2.2 2 0 0 2 2 2 0 ENTH domain TIP120 PF08623.10 OAG01519.1 - 3.5 7.4 6.4 18 5.1 0.1 3.4 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) DUF1077 PF06417.12 OAG01520.1 - 1.7e-45 153.8 1.8 2.1e-45 153.5 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Pkinase PF00069.25 OAG01521.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LCCL PF03815.19 OAG01522.1 - 7.4e-21 74.1 0.0 1.3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 LCCL domain CDH-cyt PF16010.5 OAG01523.1 - 1e-14 54.6 0.0 2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 OAG01523.1 - 1.2e-09 37.9 1.5 2.7e-09 36.8 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 OAG01523.1 - 5.6e-09 36.2 6.6 1.1e-08 35.2 6.6 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 OAG01523.1 - 0.018 15.2 6.6 0.034 14.3 3.3 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF4079) CBP_BcsF PF11120.8 OAG01523.1 - 0.087 12.9 0.7 7.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF DUF1361 PF07099.11 OAG01523.1 - 0.096 12.7 0.6 0.19 11.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) GT87 PF09594.10 OAG01523.1 - 0.1 12.3 3.7 0.21 11.3 3.7 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 87 FeoB_associated PF12669.7 OAG01523.1 - 0.81 10.1 3.3 3.7 8.0 0.7 2.7 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF202 PF02656.15 OAG01523.1 - 1.1 9.8 11.6 0.17 12.4 0.8 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) MerC PF03203.14 OAG01523.1 - 1.1 9.7 9.2 1.7e+02 2.7 9.4 3.1 1 1 0 1 1 1 0 MerC mercury resistance protein ABC2_membrane PF01061.24 OAG01524.1 - 6.8e-82 274.0 69.6 4.1e-43 147.2 22.7 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAG01524.1 - 3.4e-38 131.2 0.0 7.3e-18 65.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG01524.1 - 4.2e-33 113.1 14.6 6.2e-29 99.7 1.4 3.7 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG01524.1 - 4.2e-15 56.1 0.5 1.6e-14 54.2 0.1 2.4 2 1 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 OAG01524.1 - 2e-06 27.8 0.2 0.00088 19.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAG01524.1 - 4.9e-06 27.0 0.1 0.0019 18.6 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAG01524.1 - 1.2e-05 25.5 0.3 0.00079 19.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG01524.1 - 0.00024 20.8 1.3 0.044 13.5 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OAG01524.1 - 0.00029 20.5 0.0 0.0039 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAG01524.1 - 0.0019 17.8 0.5 0.11 12.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 OAG01524.1 - 0.0022 17.2 23.5 0.0022 17.2 23.5 4.7 3 2 0 3 3 2 1 ABC-2 family transporter protein AAA_18 PF13238.6 OAG01524.1 - 0.0037 17.8 0.1 0.032 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG01524.1 - 0.0039 17.5 0.0 1.7 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAG01524.1 - 0.0099 15.3 0.0 1.1 8.7 0.0 3.2 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 OAG01524.1 - 0.012 15.4 0.1 0.87 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG01524.1 - 0.012 14.7 0.3 0.058 12.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.6 OAG01524.1 - 0.013 15.9 0.7 1.4 9.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 OAG01524.1 - 0.022 14.7 0.4 2 8.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 OAG01524.1 - 0.023 14.5 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAG01524.1 - 0.039 14.1 0.1 9.7 6.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 OAG01524.1 - 0.11 12.5 0.2 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 OAG01524.1 - 0.12 12.8 0.0 19 5.7 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 OAG01524.1 - 0.15 12.5 0.1 10 6.6 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OAG01524.1 - 0.16 12.4 0.0 0.53 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain GUN4 PF05419.12 OAG01525.1 - 0.12 12.5 0.1 0.22 11.6 0.1 1.6 1 1 0 1 1 1 0 GUN4-like Allexi_40kDa PF05549.11 OAG01526.1 - 0.029 13.9 7.9 0.028 13.9 6.4 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein Matrilin_ccoil PF10393.9 OAG01526.1 - 0.24 11.3 8.0 16 5.4 0.8 3.6 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Muted PF14942.6 OAG01526.1 - 7.7 6.9 9.7 12 6.3 8.2 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein AA_permease PF00324.21 OAG01527.1 - 5.7e-102 341.8 41.9 6.8e-102 341.5 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG01527.1 - 1.3e-27 96.7 43.3 1.8e-27 96.2 43.3 1.2 1 0 0 1 1 1 1 Amino acid permease VirB3 PF05101.13 OAG01527.1 - 0.045 14.0 1.2 0.045 14.0 1.2 4.5 4 1 0 4 4 4 0 Type IV secretory pathway, VirB3-like protein DUF3302 PF11742.8 OAG01527.1 - 9.2 6.5 9.7 4 7.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) Lipase_GDSL_2 PF13472.6 OAG01528.1 - 4.7e-20 72.7 0.0 7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG01528.1 - 1.7e-13 51.0 0.0 2.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1770 PF08589.10 OAG01530.1 - 7.3e-31 107.1 0.8 9.6e-31 106.7 0.8 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) EF-hand_1 PF00036.32 OAG01531.1 - 2.3e-27 92.4 11.8 2.4e-07 29.8 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAG01531.1 - 2.9e-23 82.1 15.1 3.1e-14 53.2 1.6 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OAG01531.1 - 1.1e-20 71.7 6.7 2.8e-05 23.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OAG01531.1 - 1.5e-18 65.3 10.4 1.5e-06 27.4 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OAG01531.1 - 1.5e-14 53.6 10.4 0.0001 22.1 0.6 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAG01531.1 - 1e-06 29.0 0.0 0.0048 17.2 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OAG01531.1 - 8.2e-06 25.7 9.2 0.0028 17.6 0.4 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OAG01531.1 - 0.058 13.6 1.9 0.12 12.5 0.6 2.4 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_9 PF14658.6 OAG01531.1 - 0.068 13.5 0.1 5 7.5 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain Methyltransf_2 PF00891.18 OAG01532.1 - 1.9e-29 102.5 0.0 3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OAG01532.1 - 6e-07 29.4 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG01532.1 - 1.2e-06 29.1 0.0 3.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG01532.1 - 6.6e-06 26.0 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG01532.1 - 3.6e-05 24.3 0.0 7.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG01532.1 - 7.1e-05 23.5 0.0 0.00019 22.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG01532.1 - 0.03 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG01532.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 OAG01532.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Helicase_PWI PF18149.1 OAG01533.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal helicase PWI domain Peptidase_M57 PF12388.8 OAG01533.1 - 0.16 11.6 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M1 PF01433.20 OAG01536.1 - 5.6e-41 140.5 0.1 8.6e-41 139.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 OAG01536.1 - 4.3e-39 133.1 0.0 8e-39 132.2 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 OAG01536.1 - 2.8e-28 99.4 0.0 4.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 OAG01536.1 - 2.3 8.6 5.0 14 6.1 2.7 2.7 2 1 0 2 2 2 0 M61 glycyl aminopeptidase GST_N PF02798.20 OAG01537.1 - 2.7e-11 43.6 0.0 4.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG01537.1 - 1.1e-10 41.4 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG01537.1 - 7.1e-10 39.0 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG01537.1 - 3.9e-09 36.6 0.0 5.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG01537.1 - 4.4e-09 36.5 0.0 6.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG01537.1 - 9.4e-08 32.4 0.0 1.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MARVEL PF01284.23 OAG01540.1 - 0.89 9.6 15.1 1.6 8.8 8.6 2.8 2 1 0 2 2 2 0 Membrane-associating domain TMEM237 PF15383.6 OAG01540.1 - 1.9 7.5 8.7 0.17 10.9 0.5 2.7 2 1 1 3 3 3 0 Transmembrane protein 237 Thioredoxin PF00085.20 OAG01541.1 - 1.1e-42 144.2 0.3 1.5e-24 85.9 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 OAG01541.1 - 5.6e-10 39.4 0.0 2.7e-05 24.2 0.0 3.6 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OAG01541.1 - 3.6e-06 26.5 0.0 0.12 11.7 0.0 3.2 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAG01541.1 - 1.1e-05 25.7 0.9 0.27 11.6 0.0 4.1 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OAG01541.1 - 2.2e-05 24.9 5.1 0.12 12.9 0.1 4.2 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OAG01541.1 - 0.001 19.1 0.0 0.13 12.3 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_7 PF13899.6 OAG01541.1 - 0.016 15.3 1.0 0.27 11.4 0.0 3.2 4 0 0 4 4 4 0 Thioredoxin-like AhpC-TSA PF00578.21 OAG01541.1 - 0.047 13.6 1.8 0.97 9.4 0.1 3.1 3 1 1 4 4 4 0 AhpC/TSA family TraF PF13728.6 OAG01541.1 - 0.26 11.1 0.1 0.26 11.1 0.1 3.2 3 1 1 4 4 4 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 OAG01541.1 - 0.56 10.3 5.9 0.33 11.1 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin ETC_C1_NDUFA5 PF04716.14 OAG01542.1 - 8e-28 96.0 0.5 4.6e-26 90.4 0.1 2.4 2 0 0 2 2 2 2 ETC complex I subunit conserved region Fungal_trans PF04082.18 OAG01544.1 - 1.8e-12 46.9 0.2 3.3e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG01544.1 - 2.9e-09 36.9 10.9 9.3e-07 29.0 4.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 OAG01544.1 - 0.019 15.3 5.6 0.041 14.2 5.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OAG01544.1 - 0.028 14.8 17.7 0.4 11.2 7.8 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG01544.1 - 0.17 12.8 26.8 0.037 14.9 6.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 OAG01544.1 - 1 9.4 3.3 2.3 8.3 3.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 OAG01544.1 - 4.5 7.3 7.1 8.9 6.3 7.1 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 OAG01544.1 - 8.1 6.9 8.9 1.5 9.2 2.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DDE_Tnp_1_assoc PF13808.6 OAG01545.1 - 0.098 12.7 0.1 8.9 6.4 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-associated Peptidase_M3 PF01432.20 OAG01546.1 - 7.9e-163 543.0 0.0 1.2e-162 542.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Imm42 PF15593.6 OAG01546.1 - 0.041 14.4 0.7 11 6.4 0.2 2.7 2 0 0 2 2 2 0 Immunity protein 42 Rhodanese PF00581.20 OAG01547.1 - 6.7e-11 42.7 0.0 8.8e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain F-box PF00646.33 OAG01549.1 - 0.026 14.4 0.2 0.068 13.1 0.2 1.8 1 0 0 1 1 1 0 F-box domain DUF2781 PF10914.8 OAG01550.1 - 1.1e-40 139.4 9.3 1.2e-40 139.3 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) TRI12 PF06609.13 OAG01551.1 - 2.1e-57 194.9 23.3 2.7e-57 194.5 23.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG01551.1 - 1.2e-22 80.4 37.9 1.2e-22 80.4 37.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily SMC_N PF02463.19 OAG01552.1 - 5.1e-71 238.6 0.0 1.2e-70 237.4 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAG01552.1 - 5.5e-23 81.5 0.6 5.4e-21 75.1 0.2 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAG01552.1 - 5.4e-11 43.4 13.8 5.4e-11 43.4 13.8 7.4 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 OAG01552.1 - 1.3e-10 41.6 1.5 2.5e-07 30.8 0.0 3.8 5 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG01552.1 - 0.00046 19.9 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 OAG01552.1 - 0.0006 19.4 14.0 0.0006 19.4 14.0 6.7 3 2 3 6 6 6 2 Mechanosensitive ion channel porin domain HIP1_clath_bdg PF16515.5 OAG01552.1 - 0.0052 17.4 4.0 0.0052 17.4 4.0 10.1 3 3 7 10 10 10 2 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 OAG01552.1 - 0.019 15.5 0.4 0.019 15.5 0.4 6.1 3 3 1 4 4 4 0 ABC transporter Zea_mays_MuDR PF05928.11 OAG01552.1 - 0.08 12.6 0.0 0.08 12.6 0.0 2.7 3 0 0 3 3 3 0 Zea mays MURB-like protein (MuDR) OPT PF03169.15 OAG01553.1 - 1.7e-128 430.0 47.7 1.9e-128 429.8 47.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NACHT PF05729.12 OAG01554.1 - 1.3e-05 25.2 0.0 3.8e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG01554.1 - 2.1e-05 24.8 0.5 0.0001 22.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG01554.1 - 0.00079 19.9 1.7 0.0037 17.7 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 OAG01554.1 - 0.0045 16.7 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain WAPL PF07814.13 OAG01554.1 - 0.016 14.0 0.6 0.029 13.2 0.6 1.4 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin ATPase_2 PF01637.18 OAG01554.1 - 0.069 13.1 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Ank PF00023.30 OAG01555.1 - 3.4e-25 87.4 0.4 9.8e-07 29.0 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OAG01555.1 - 7.3e-24 81.3 0.1 3.7e-06 26.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 OAG01555.1 - 2.8e-22 79.1 0.0 2.5e-09 37.6 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG01555.1 - 1.3e-19 70.0 0.2 2.8e-09 37.0 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG01555.1 - 2.4e-19 69.4 0.0 2.9e-07 30.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) OGFr_N PF04664.13 OAG01556.1 - 3.5e-18 65.9 0.1 8e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region NDUF_B4 PF07225.12 OAG01557.1 - 3.7e-05 23.6 0.1 3.9e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_N PF02798.20 OAG01558.1 - 1.1e-11 44.9 0.0 2.6e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG01558.1 - 2.2e-08 34.3 0.0 4.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG01558.1 - 4.7e-07 30.1 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG01558.1 - 6.3e-07 29.5 0.1 1.4e-06 28.4 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG01558.1 - 2.9e-06 27.4 0.1 4.9e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG01558.1 - 2.8e-05 24.1 0.0 7.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.22 OAG01559.1 - 0.00039 20.7 0.0 0.009 16.3 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain PHD PF00628.29 OAG01561.1 - 0.69 9.8 12.7 0.02 14.8 6.5 1.7 2 0 0 2 2 2 0 PHD-finger adh_short_C2 PF13561.6 OAG01562.1 - 3.1e-38 131.6 0.0 1.2e-19 70.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG01562.1 - 1e-28 100.1 0.2 2.7e-27 95.5 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG01562.1 - 9.6e-09 35.4 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.23 OAG01563.1 - 9.8e-23 80.4 1.6 1.5e-22 79.8 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG01563.1 - 2.6e-14 53.0 1.8 3.7e-14 52.5 0.1 2.1 2 0 0 2 2 2 1 Berberine and berberine like KAsynt_C_assoc PF16197.5 OAG01563.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Melibiase_2 PF16499.5 OAG01564.1 - 4e-57 193.6 4.8 5.9e-39 133.9 0.9 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 OAG01564.1 - 2.4e-13 50.0 2.5 2.6e-11 43.4 0.0 2.9 3 0 0 3 3 3 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG01564.1 - 7.6e-06 25.1 0.8 9.9e-06 24.7 0.0 1.5 2 0 0 2 2 2 1 Melibiase EBP PF05241.12 OAG01565.1 - 3.2e-55 186.3 7.6 4.1e-55 186.0 7.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein RhoGEF PF00621.20 OAG01566.1 - 0.069 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 RhoGEF domain Zn_clus PF00172.18 OAG01568.1 - 4.5e-09 36.3 13.8 7.3e-09 35.6 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG01568.1 - 2.4e-06 26.6 1.2 3.5e-06 26.1 0.2 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_125 PF06824.11 OAG01569.1 - 4.8e-185 615.3 0.1 5.7e-185 615.1 0.1 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DASH_Dam1 PF08653.10 OAG01569.1 - 0.13 12.1 0.6 0.62 9.9 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 AMPK1_CBM PF16561.5 OAG01571.1 - 0.13 12.5 0.0 4 7.7 0.0 2.3 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Adap_comp_sub PF00928.21 OAG01572.1 - 2.9e-18 66.2 0.0 4.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG01572.1 - 8e-07 29.1 0.2 1.3e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 OAG01572.1 - 0.00012 22.4 1.8 0.002 18.6 0.3 2.4 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) MAGE_N PF12440.8 OAG01572.1 - 0.29 11.8 9.7 0.12 13.0 2.3 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF2420 PF10336.9 OAG01573.1 - 1.8e-13 50.5 0.0 2.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.14 OAG01574.1 - 6.2e-104 347.2 14.6 7.2e-104 347.0 14.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAG01574.1 - 5.3e-05 23.4 7.2 5.3e-05 23.4 7.2 3.5 3 1 0 3 3 3 2 EamA-like transporter family ANAPC4 PF12896.7 OAG01575.1 - 2.6e-54 183.9 0.1 3.6e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 OAG01575.1 - 1.4e-23 83.0 0.0 3.4e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L2_C PF03947.18 OAG01576.1 - 1.6e-41 141.4 3.4 2.8e-41 140.6 3.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAG01576.1 - 1.5e-13 50.5 0.1 3.5e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain F-box-like PF12937.7 OAG01577.1 - 0.0036 17.2 0.0 0.013 15.4 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG01577.1 - 0.0048 16.7 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain Sulfotransfer_3 PF13469.6 OAG01579.1 - 0.085 13.2 0.3 3.5 8.0 0.0 3.1 1 1 0 1 1 1 0 Sulfotransferase family HET PF06985.11 OAG01582.1 - 5.8e-09 36.5 0.0 7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhoD PF09423.10 OAG01583.1 - 5.8e-113 377.5 1.2 7.3e-113 377.1 1.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAG01583.1 - 5.2e-34 116.7 0.3 1.4e-33 115.3 0.3 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OAG01583.1 - 0.00033 21.1 2.8 0.001 19.6 1.6 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Polyketide_cyc2 PF10604.9 OAG01584.1 - 1.7e-07 31.6 0.2 2.1e-07 31.3 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport LBR_tudor PF09465.10 OAG01584.1 - 0.068 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Spt20 PF12090.8 OAG01585.1 - 1.4e-38 132.9 0.0 1.4e-38 132.9 0.0 7.4 2 2 3 5 5 5 1 Spt20 family Glyco_hydro_1 PF00232.18 OAG01586.1 - 1.1e-111 373.5 4.3 1.6e-111 373.0 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 OAG01586.1 - 0.022 13.9 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 DUF3429 PF11911.8 OAG01587.1 - 0.042 14.2 0.3 0.065 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) ALO PF04030.14 OAG01588.1 - 4.9e-84 282.2 0.5 9.8e-84 281.2 0.5 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OAG01588.1 - 3e-31 108.0 0.3 4.4e-31 107.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain gag_pre-integrs PF13976.6 OAG01588.1 - 7.2 6.5 8.5 56 3.7 0.0 4.1 2 2 2 4 4 4 0 GAG-pre-integrase domain DUF3328 PF11807.8 OAG01589.1 - 3.2e-32 112.1 0.5 3.9e-32 111.8 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SAD_SRA PF02182.17 OAG01590.1 - 3.6e-07 30.0 0.1 1.2e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 SAD/SRA domain Methyltr_RsmB-F PF01189.17 OAG01591.1 - 2.4e-18 66.5 0.0 9.9e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Arf PF00025.21 OAG01592.1 - 1.2e-41 142.1 0.0 4e-26 91.5 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 OAG01592.1 - 3e-14 52.9 0.0 1.5e-08 34.2 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAG01592.1 - 4.3e-11 42.7 0.0 3e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG01592.1 - 6.4e-11 42.5 0.0 1.9e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG01592.1 - 1.9e-06 27.4 0.0 3.3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAG01592.1 - 1.2e-05 24.7 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG01592.1 - 3e-05 24.1 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG01592.1 - 0.00046 19.8 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OAG01592.1 - 0.055 13.0 0.1 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Sugar_tr PF00083.24 OAG01594.1 - 1.3e-109 367.1 26.5 1.5e-109 366.9 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01594.1 - 1.9e-21 76.4 31.0 2.8e-14 52.8 6.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pro_Al_protease PF02983.14 OAG01595.1 - 1.7e-13 50.4 2.9 1.7e-13 50.4 1.0 2.1 2 0 0 2 2 2 1 Alpha-lytic protease prodomain Cupin_1 PF00190.22 OAG01596.1 - 4.2e-42 143.3 0.0 7.2e-21 74.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAG01596.1 - 2.4e-26 91.2 0.7 2.9e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG01596.1 - 1.1e-10 41.0 0.0 0.00017 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAG01596.1 - 4.3e-08 33.2 0.2 0.0011 18.9 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 OAG01596.1 - 0.014 15.6 0.0 5.3 7.3 0.0 2.7 3 0 0 3 3 3 0 Mif2/CENP-C like ARD PF03079.14 OAG01596.1 - 0.034 14.3 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family Cupin_6 PF12852.7 OAG01596.1 - 0.051 13.3 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Cupin DUF1275 PF06912.11 OAG01597.1 - 6e-48 163.3 14.2 7.3e-48 163.1 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_Mycoplasma PF07672.13 OAG01597.1 - 0.0012 18.2 1.0 0.0018 17.6 1.0 1.4 1 0 0 1 1 1 1 Mycoplasma MFS transporter CitMHS PF03600.16 OAG01597.1 - 1.2 8.3 11.7 2.2 7.4 11.7 1.4 1 1 0 1 1 1 0 Citrate transporter Arrestin_N PF00339.29 OAG01598.1 - 0.071 13.2 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain ASXH PF13919.6 OAG01599.1 - 3.1e-21 75.9 0.3 5.2e-21 75.1 0.3 1.4 1 0 0 1 1 1 1 Asx homology domain SOG2 PF10428.9 OAG01599.1 - 0.13 11.4 12.2 0.18 11.0 12.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Longin PF13774.6 OAG01600.1 - 1.7e-20 72.9 0.0 3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OAG01600.1 - 1.5e-15 56.7 0.0 2.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 OAG01600.1 - 0.017 15.1 0.7 0.8 9.6 0.8 2.1 1 1 1 2 2 2 0 Protein SLM4 FANCI_S3 PF14677.6 OAG01600.1 - 0.03 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 IMD PF08397.11 OAG01600.1 - 0.3 10.5 2.5 0.49 9.7 1.3 1.8 2 0 0 2 2 2 0 IRSp53/MIM homology domain Abhydrolase_6 PF12697.7 OAG01601.1 - 2.2e-17 64.4 0.1 2.6e-17 64.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tyrosinase PF00264.20 OAG01602.1 - 9.5e-33 114.4 0.7 1.4e-32 113.8 0.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Hydrolase PF00702.26 OAG01604.1 - 0.0021 18.4 0.0 0.0031 17.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG01604.1 - 0.004 17.3 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAG01604.1 - 0.0079 16.3 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Radical_SAM PF04055.21 OAG01604.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily Ribosomal_L28e PF01778.17 OAG01605.1 - 9.2e-33 113.4 0.3 1.5e-32 112.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 OAG01605.1 - 5.7e-28 97.5 8.0 5.7e-28 97.5 8.0 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 OAG01605.1 - 1.8e-05 24.3 12.4 2.3e-05 23.9 12.4 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 OAG01605.1 - 0.033 12.4 21.7 0.0052 15.1 17.9 1.6 2 0 0 2 2 2 0 Nop14-like family TFIIA PF03153.13 OAG01605.1 - 0.041 13.9 9.1 0.051 13.6 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PYC_OADA PF02436.18 OAG01605.1 - 0.17 11.6 0.2 0.41 10.4 0.1 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Cwf_Cwc_15 PF04889.12 OAG01605.1 - 3.3 7.4 31.2 34 4.1 31.2 2.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 OAG01605.1 - 8.5 5.0 9.2 14 4.3 6.8 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TrmE_N PF10396.9 OAG01606.1 - 3.6e-34 117.5 0.1 2.1e-33 115.1 0.0 2.3 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 OAG01606.1 - 4.5e-27 95.6 0.5 6.4e-27 95.1 0.5 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 OAG01606.1 - 1.7e-19 70.0 0.1 3.3e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG01606.1 - 1.8e-11 43.8 0.1 3.1e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG01606.1 - 5.4e-09 35.9 0.1 7.7e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAG01606.1 - 1.1e-05 25.5 0.0 2.7e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 OAG01606.1 - 0.00013 21.9 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 OAG01606.1 - 0.043 14.3 0.4 0.095 13.2 0.4 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAG01606.1 - 0.069 12.9 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG01606.1 - 0.14 11.8 0.6 8.4 5.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HET PF06985.11 OAG01609.1 - 6.2e-25 88.3 0.0 1.1e-24 87.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hus1 PF04005.12 OAG01610.1 - 1.6e-98 329.4 0.0 1.8e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Peptidase_A4 PF01828.17 OAG01611.1 - 4e-34 117.9 9.1 4.5e-34 117.7 9.1 1.0 1 0 0 1 1 1 1 Peptidase A4 family DUF1996 PF09362.10 OAG01612.1 - 2.1e-79 266.8 2.2 2.6e-79 266.5 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TRAPPC10 PF12584.8 OAG01614.1 - 4e-34 117.6 0.0 7.1e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 OAG01614.1 - 0.0035 17.0 0.1 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 Foie gras liver health family 1 TPR_19 PF14559.6 OAG01614.1 - 0.087 13.3 0.4 1.9 9.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RTA1 PF04479.13 OAG01615.1 - 4.4e-50 170.2 5.3 6.7e-50 169.6 5.3 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4173 PF13777.6 OAG01615.1 - 0.0077 15.7 2.2 0.018 14.5 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4173) DUF1275 PF06912.11 OAG01615.1 - 1.6 8.6 8.4 1.3 8.9 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) Rep_fac_C PF08542.11 OAG01616.1 - 1.9e-24 85.8 0.2 6.3e-24 84.2 0.0 2.0 3 0 0 3 3 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OAG01616.1 - 2.3e-12 47.0 0.0 1.2e-08 34.9 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 OAG01616.1 - 6.5e-11 42.8 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAG01616.1 - 7.7e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG01616.1 - 3.2e-06 27.6 0.0 0.00016 22.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 OAG01616.1 - 2.6e-05 24.1 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OAG01616.1 - 5.2e-05 23.5 0.1 0.12 12.7 0.0 2.7 2 1 1 3 3 2 2 AAA domain RuvB_N PF05496.12 OAG01616.1 - 7.8e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 OAG01616.1 - 0.00016 21.5 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 OAG01616.1 - 0.00018 21.4 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG01616.1 - 0.0025 17.8 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 OAG01616.1 - 0.0032 16.9 0.0 0.022 14.1 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 OAG01616.1 - 0.0053 15.8 0.0 0.0093 15.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_assoc_2 PF16193.5 OAG01616.1 - 0.0083 16.4 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 OAG01616.1 - 0.0091 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RGS12_usC PF16612.5 OAG01616.1 - 0.01 16.3 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal unstructured region of RGS12 NTPase_1 PF03266.15 OAG01616.1 - 0.016 15.1 0.2 0.08 12.9 0.1 2.2 2 2 1 3 3 3 0 NTPase AAA_19 PF13245.6 OAG01616.1 - 0.022 15.1 0.2 0.093 13.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAG01616.1 - 0.025 14.0 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 OAG01616.1 - 0.028 14.1 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OAG01616.1 - 0.034 13.9 0.1 1.2 8.9 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 OAG01616.1 - 0.049 13.4 0.1 0.15 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 OAG01616.1 - 0.062 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 OAG01616.1 - 0.17 11.5 0.1 0.78 9.3 0.0 2.0 2 1 1 3 3 3 0 AAA domain Asp PF00026.23 OAG01617.1 - 8.3e-71 239.0 4.0 9.9e-71 238.7 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG01617.1 - 2.2e-14 54.1 2.6 1.3e-13 51.6 1.1 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG01617.1 - 0.00012 22.6 0.1 0.41 11.3 0.0 3.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG01617.1 - 0.012 16.2 0.0 2 9.0 0.0 2.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAG01617.1 - 0.021 14.6 0.0 0.43 10.4 0.0 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal CC PF04942.14 OAG01618.1 - 0.098 12.9 0.4 0.43 10.8 0.1 2.1 2 0 0 2 2 2 0 CC domain Aldedh PF00171.22 OAG01619.1 - 3.8e-164 546.6 0.3 4.3e-164 546.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG01619.1 - 0.012 15.1 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) HCO3_cotransp PF00955.21 OAG01620.1 - 6.4e-85 285.9 16.9 5.3e-46 157.5 7.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family RNA_pol_Rpc82 PF05645.13 OAG01622.1 - 1.7e-44 152.5 0.0 1.2e-39 136.6 0.0 2.9 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 OAG01622.1 - 9.4e-14 51.3 1.4 3.5e-11 43.0 0.2 3.7 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 OAG01622.1 - 9.9e-05 22.2 1.0 0.65 9.9 0.0 2.8 2 0 0 2 2 2 2 TFIIE alpha subunit HTH_IclR PF09339.10 OAG01622.1 - 0.037 13.8 0.4 4.8 7.1 0.0 3.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain B-block_TFIIIC PF04182.12 OAG01622.1 - 0.064 13.4 0.1 1.9 8.7 0.0 2.7 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC Peptidase_M16 PF00675.20 OAG01623.1 - 7.2e-14 52.0 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAG01623.1 - 9.1e-10 38.8 0.0 2e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain CBFD_NFYB_HMF PF00808.23 OAG01624.1 - 0.0014 18.8 0.0 0.0016 18.7 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 OAG01624.1 - 0.036 14.3 0.1 0.042 14.1 0.1 1.3 1 1 0 1 1 1 0 CENP-W protein Mak10 PF04112.13 OAG01625.1 - 9.3e-61 204.2 0.0 1.4e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 OAG01626.1 - 1.2e-22 79.6 2.9 1.2e-22 79.6 2.9 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Proteasome PF00227.26 OAG01627.1 - 5.2e-49 166.3 0.0 6.8e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG01627.1 - 1e-10 41.1 1.1 1.2e-10 40.9 0.2 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 OAG01627.1 - 0.063 13.2 0.6 4.9 7.1 0.0 2.9 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK DUF1403 PF07183.11 OAG01627.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) Vps55 PF04133.14 OAG01628.1 - 1.5e-42 144.3 7.2 1.7e-42 144.1 7.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 OAG01628.1 - 0.098 12.1 0.3 0.098 12.1 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) UPF0220 PF05255.11 OAG01629.1 - 1.1e-71 239.7 2.7 1.3e-71 239.5 2.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Abhydrolase_1 PF00561.20 OAG01631.1 - 8e-12 45.3 0.0 4.6e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG01631.1 - 2.6e-08 33.4 0.0 7.4e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG01631.1 - 7.1e-05 23.5 0.1 0.00011 22.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 OAG01631.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Cohesin_load PF10345.9 OAG01632.1 - 1.2e-124 417.0 0.8 1.4e-124 416.8 0.8 1.0 1 0 0 1 1 1 1 Cohesin loading factor SIMPL PF04402.14 OAG01634.1 - 7.6e-17 62.4 0.1 8.8e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) HAD_2 PF13419.6 OAG01635.1 - 3.8e-06 27.1 0.0 1.6e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG01635.1 - 0.00014 22.3 0.0 0.00017 21.9 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OAG01637.1 - 3.6e-53 180.6 0.0 5.3e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG01637.1 - 1.7e-30 106.2 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG01637.1 - 4.5e-10 39.3 0.0 1.1e-07 31.5 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 OAG01637.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG01637.1 - 0.042 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med6 PF04934.14 OAG01638.1 - 4e-19 68.7 0.4 6.8e-19 68.0 0.1 1.5 2 0 0 2 2 2 1 MED6 mediator sub complex component Trs65 PF12735.7 OAG01638.1 - 1.2 8.5 4.8 2.1 7.7 4.8 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 SRP9-21 PF05486.12 OAG01638.1 - 2.9 8.4 7.2 2.5 8.6 1.1 2.8 2 1 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) MMtag PF10159.9 OAG01639.1 - 6.7e-32 109.6 4.4 6.7e-32 109.6 4.4 2.4 2 1 0 2 2 2 1 Multiple myeloma tumor-associated RR_TM4-6 PF06459.12 OAG01639.1 - 5.5 6.7 15.0 6.9 6.4 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 OAG01639.1 - 7.1 4.8 24.7 8.3 4.6 24.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Transformer PF06495.11 OAG01639.1 - 8.6 6.4 27.4 12 6.0 27.4 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Amidase PF01425.21 OAG01640.1 - 1.4e-83 281.3 0.0 5.6e-83 279.4 0.0 1.8 1 1 0 1 1 1 1 Amidase RAD51_interact PF15696.5 OAG01640.1 - 0.032 14.3 0.8 0.067 13.3 0.8 1.5 1 0 0 1 1 1 0 RAD51 interacting motif DUF4342 PF14242.6 OAG01642.1 - 3.6 7.7 4.4 0.74 9.8 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) HET PF06985.11 OAG01643.1 - 4.7e-35 121.1 0.0 1.9e-33 115.9 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Stealth_CR4 PF17103.5 OAG01643.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 MFS_1 PF07690.16 OAG01644.1 - 1.2e-22 80.4 38.3 1.2e-22 80.4 38.3 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG01644.1 - 1.2e-13 50.4 21.9 3.3e-07 29.1 15.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1981 PF09324.10 OAG01644.1 - 0.11 12.4 0.8 0.43 10.5 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) dCMP_cyt_deam_1 PF00383.23 OAG01645.1 - 1.8e-08 34.2 0.2 4.4e-08 32.9 0.2 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG01645.1 - 0.0009 19.0 1.1 0.0033 17.2 0.2 2.0 2 0 0 2 2 2 1 MafB19-like deaminase ORC5_C PF14630.6 OAG01646.1 - 3.7e-77 259.7 0.0 4.7e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OAG01646.1 - 2.4e-12 47.6 0.0 5e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG01646.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0061 PF02696.14 OAG01647.1 - 4.3e-136 454.4 0.0 5.8e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Lipase_GDSL_2 PF13472.6 OAG01649.1 - 0.00015 22.3 0.0 0.00022 21.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG01649.1 - 0.039 13.9 0.0 1.3 9.0 0.0 2.1 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF202 PF02656.15 OAG01650.1 - 1.2e-15 57.7 1.9 5.3e-15 55.6 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1691 PF07950.11 OAG01650.1 - 0.047 14.4 0.6 0.091 13.5 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1691) MNHE PF01899.16 OAG01651.1 - 0.051 13.3 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Glyco_hydro_61 PF03443.14 OAG01653.1 - 1.3e-65 221.2 1.6 1.6e-65 220.9 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 OAG01653.1 - 0.017 14.6 0.6 0.039 13.4 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase NPCBM_assoc PF10633.9 OAG01653.1 - 0.04 14.2 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase zinc_ribbon_9 PF14369.6 OAG01653.1 - 0.085 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon Peptidase_M1 PF01433.20 OAG01654.1 - 5.6e-85 284.3 3.8 8.5e-85 283.7 3.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OAG01654.1 - 2.1e-80 270.6 0.0 5e-80 269.4 0.0 1.7 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OAG01654.1 - 1.1e-45 156.1 2.7 3.9e-45 154.3 0.8 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain BC10 PF06726.12 OAG01654.1 - 9.4e-12 45.0 9.8 1.4e-11 44.5 8.7 1.8 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 DUF45 PF01863.17 OAG01654.1 - 0.12 12.4 0.1 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 LisH_2 PF16045.5 OAG01654.1 - 0.17 10.9 0.1 0.43 9.7 0.1 1.7 1 0 0 1 1 1 0 LisH NCE101 PF11654.8 OAG01655.1 - 1.1e-11 44.3 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 Atg8 PF02991.16 OAG01656.1 - 2.4e-51 172.3 0.3 2.8e-51 172.0 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OAG01656.1 - 3.2e-06 27.5 0.0 3.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 OAG01657.1 - 1.1e-146 487.3 0.1 1.2e-146 487.0 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Peptidase_M43 PF05572.13 OAG01659.1 - 2.3e-13 50.4 3.2 5.2e-13 49.2 3.2 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OAG01659.1 - 2.9e-07 30.8 0.1 5.9e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OAG01659.1 - 8.6e-06 26.3 0.1 2.3e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAG01659.1 - 0.00049 19.8 0.6 0.0012 18.5 0.1 1.8 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAG01659.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 Matrixin CDC50 PF03381.15 OAG01660.1 - 1.4e-96 323.3 0.0 1.9e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Asp4 PF16996.5 OAG01660.1 - 0.15 11.8 3.7 0.38 10.6 2.3 2.4 2 1 0 2 2 2 0 Accessory secretory protein Sec Asp4 SWIRM PF04433.17 OAG01661.1 - 5.6e-11 42.6 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIM PF04434.17 OAG01663.1 - 0.077 12.7 0.2 0.077 12.7 0.2 2.3 2 0 0 2 2 2 0 SWIM zinc finger MitMem_reg PF13012.6 OAG01664.1 - 2.8e-37 127.6 0.0 4.7e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAG01664.1 - 6.6e-31 106.7 0.0 1.2e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 OAG01664.1 - 0.017 14.8 3.5 0.025 14.3 3.5 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Pex16 PF08610.10 OAG01665.1 - 2.6e-141 470.5 0.1 3e-141 470.3 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) HD PF01966.22 OAG01666.1 - 1.2e-08 35.2 0.6 2.1e-08 34.4 0.6 1.4 1 0 0 1 1 1 1 HD domain Melibiase_2_C PF17450.2 OAG01666.1 - 0.12 12.6 0.0 9.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain PDEase_I PF00233.19 OAG01666.1 - 0.32 10.7 2.0 0.71 9.5 0.7 1.9 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Glyco_hydro_17 PF00332.18 OAG01667.1 - 1.6e-05 24.7 1.2 2.9e-05 23.8 0.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 But2 PF09792.9 OAG01668.1 - 1.1e-29 103.7 0.2 1.1e-29 103.7 0.2 1.5 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Peptidase_S51 PF03575.17 OAG01669.1 - 3.9e-22 78.9 0.0 4.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 FAD_binding_6 PF00970.24 OAG01670.1 - 2.2e-09 37.5 0.0 5.1e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG01670.1 - 2.2e-06 28.3 0.0 7.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG01670.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain MFS_1 PF07690.16 OAG01671.1 - 4.2e-39 134.5 47.6 6e-38 130.7 49.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG01671.1 - 6.3e-06 24.9 10.9 1.7e-05 23.4 10.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SP24 PF16504.5 OAG01671.1 - 0.78 9.8 5.5 0.15 12.1 0.9 2.1 2 0 0 2 2 2 0 Putative virion membrane protein of plant and insect virus Sugar_tr PF00083.24 OAG01672.1 - 4.1e-81 273.2 17.2 4.7e-81 273.0 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01672.1 - 1.8e-17 63.3 15.1 2.3e-12 46.5 0.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG01672.1 - 0.2 10.5 11.5 0.011 14.7 5.0 2.0 2 0 0 2 2 2 0 MFS_1 like family 6PF2K PF01591.18 OAG01673.1 - 7.8e-74 247.7 0.2 1e-52 178.7 0.1 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG01673.1 - 1.6e-29 103.0 0.0 4.3e-22 78.7 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAG01673.1 - 0.17 12.0 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF202 PF02656.15 OAG01674.1 - 0.012 16.0 7.4 0.045 14.2 7.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) CbiQ PF02361.16 OAG01674.1 - 0.026 14.1 1.4 0.03 14.0 1.4 1.1 1 0 0 1 1 1 0 Cobalt transport protein Cauli_VI PF01693.16 OAG01676.1 - 2.3e-34 117.4 7.7 3.7e-17 62.3 0.9 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 OAG01676.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 RNase H Big_2 PF02368.18 OAG01678.1 - 8.7 6.3 11.5 0.15 12.0 3.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) F-box-like PF12937.7 OAG01679.1 - 8.2e-08 32.0 0.4 2e-07 30.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG01679.1 - 6.5e-07 29.1 0.5 1.6e-06 27.8 0.5 1.7 1 0 0 1 1 1 1 F-box domain SAE2 PF08573.10 OAG01680.1 - 5.2e-29 101.6 3.2 3.1e-28 99.1 0.0 2.8 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4951 PF16309.5 OAG01680.1 - 0.00019 21.4 0.4 0.00048 20.1 0.4 1.6 1 0 0 1 1 1 1 Domian of unknown function (DUF4951) ZapB PF06005.12 OAG01680.1 - 0.0002 21.7 1.7 0.0002 21.7 1.7 2.5 2 0 0 2 2 2 1 Cell division protein ZapB DUF4527 PF15030.6 OAG01680.1 - 0.013 14.9 1.3 0.033 13.6 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) YabA PF06156.13 OAG01680.1 - 0.039 14.6 7.3 0.3 11.7 1.4 2.5 2 0 0 2 2 2 0 Initiation control protein YabA LprI PF07007.12 OAG01680.1 - 0.039 14.6 0.4 0.12 13.1 0.4 1.8 1 0 0 1 1 1 0 Lysozyme inhibitor LprI WRC PF08879.10 OAG01680.1 - 0.046 13.4 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 WRC DUF573 PF04504.14 OAG01680.1 - 0.086 13.5 2.6 0.27 11.9 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 CtIP_N PF10482.9 OAG01680.1 - 1.7 8.7 6.2 2.1 8.4 1.8 2.4 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain NYD-SP28_assoc PF14775.6 OAG01680.1 - 3.2 7.9 5.7 30 4.8 0.2 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Rad51 PF08423.11 OAG01681.1 - 4.2e-11 42.6 0.0 5.7e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 OAG01681.1 - 0.0029 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 OAG01681.1 - 0.023 14.2 0.7 0.05 13.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG01681.1 - 0.025 15.1 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RecA PF00154.21 OAG01681.1 - 0.039 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_16 PF13191.6 OAG01681.1 - 0.042 14.2 0.3 0.095 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAG01681.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAG01681.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 OAG01681.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 OAG01681.1 - 0.25 10.5 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Carn_acyltransf PF00755.20 OAG01682.1 - 5.6e-205 682.4 0.0 8.1e-205 681.9 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-rbx1 PF12678.7 OAG01682.1 - 0.032 14.5 0.2 0.094 13.0 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Amidase PF01425.21 OAG01684.1 - 1.4e-84 284.7 0.2 1.9e-84 284.2 0.2 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 OAG01685.1 - 1.1e-12 48.0 0.0 1.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.18 OAG01686.1 - 6.5e-28 97.5 0.3 8.7e-28 97.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01686.1 - 2.7e-08 33.8 12.6 5.2e-08 32.9 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG01687.1 - 2.8e-46 158.0 45.3 3.9e-44 151.0 46.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG01687.1 - 1.4e-11 43.6 20.8 6.3e-11 41.4 20.8 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG01687.1 - 7.9e-11 41.5 12.4 7.9e-11 41.5 12.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG01687.1 - 0.00013 21.4 3.8 0.00013 21.4 3.8 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1430 PF07242.11 OAG01687.1 - 0.25 11.6 4.2 0.2 12.0 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) HlyIII PF03006.20 OAG01687.1 - 1.2 8.8 18.5 0.095 12.4 11.9 2.5 2 1 0 2 2 2 0 Haemolysin-III related Transp_cyt_pur PF02133.15 OAG01688.1 - 6.3e-85 285.6 39.2 7.3e-85 285.4 39.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ldr_toxin PF13940.6 OAG01688.1 - 5.3 7.2 7.7 5.2 7.2 1.8 3.3 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system TRAPPC9-Trs120 PF08626.11 OAG01692.1 - 0 1455.5 0.0 0 1455.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 OAG01692.1 - 0.016 15.5 0.1 0.034 14.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3684 PF12449.8 OAG01693.1 - 0 1170.7 0.0 0 1170.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) WLM PF08325.10 OAG01693.1 - 3.4e-06 27.3 0.1 9.8e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 WLM domain HATPase_c_3 PF13589.6 OAG01693.1 - 0.0067 16.3 0.0 0.02 14.8 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ThrE_2 PF12821.7 OAG01693.1 - 0.017 15.2 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE zf-CCCH PF00642.24 OAG01694.1 - 0.0047 16.8 2.7 0.0047 16.8 2.7 2.8 2 1 1 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAG01694.1 - 0.026 14.3 4.3 0.026 14.3 4.3 3.5 3 0 0 3 3 3 0 CCCH-type zinc finger DUF349 PF03993.12 OAG01694.1 - 0.039 14.2 0.6 0.097 13.0 0.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DivIVA PF05103.13 OAG01694.1 - 0.27 11.3 2.2 0.59 10.2 1.1 2.0 2 0 0 2 2 2 0 DivIVA protein Torus PF16131.5 OAG01694.1 - 0.41 11.3 0.1 0.41 11.3 0.1 2.5 3 1 0 3 3 3 0 Torus domain zf_CCCH_4 PF18345.1 OAG01694.1 - 1.7 8.8 12.2 0.35 11.0 7.2 2.5 2 0 0 2 2 2 0 Zinc finger domain GST_C_3 PF14497.6 OAG01695.1 - 2.1e-27 95.2 0.1 4.2e-27 94.2 0.1 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG01695.1 - 2.2e-05 24.4 0.4 4.8e-05 23.3 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG01695.1 - 5.1e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_S7e PF01251.18 OAG01696.1 - 4.9e-80 267.6 0.1 5.7e-80 267.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e MIP PF00230.20 OAG01697.1 - 6.8e-31 107.7 12.8 8.2e-31 107.5 12.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein PHD PF00628.29 OAG01699.1 - 2e-06 27.6 5.5 3.4e-06 26.8 5.5 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 OAG01699.1 - 0.004 17.7 0.0 0.0095 16.5 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H_2 PF13832.6 OAG01699.1 - 0.082 13.1 0.9 0.14 12.3 0.9 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Arg_decarbox_C PF17944.1 OAG01699.1 - 0.098 13.2 0.2 22 5.7 0.1 2.6 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension zf-HC5HC2H PF13771.6 OAG01699.1 - 0.5 10.6 1.7 0.92 9.8 1.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Dynamin_N PF00350.23 OAG01701.1 - 1.4e-16 61.1 2.2 1.4e-15 57.8 0.0 3.4 2 2 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OAG01701.1 - 5.9e-06 26.4 0.1 0.00011 22.2 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG01701.1 - 0.001 19.0 0.7 0.0047 16.8 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 OAG01701.1 - 0.0013 19.3 0.0 0.0013 19.3 0.0 2.5 2 1 0 2 2 2 1 ABC transporter IIGP PF05049.13 OAG01701.1 - 0.0015 17.7 0.0 0.0042 16.2 0.0 1.7 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Wtap PF17098.5 OAG01701.1 - 0.0047 16.9 2.7 0.013 15.5 0.6 2.7 2 1 0 2 2 2 1 WTAP/Mum2p family AIG1 PF04548.16 OAG01701.1 - 0.016 14.6 0.0 0.091 12.1 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 OAG01701.1 - 0.02 15.2 0.0 0.11 12.8 0.0 2.3 1 0 0 1 1 1 0 AAA domain PBP1_TM PF14812.6 OAG01701.1 - 0.052 13.9 8.0 0.25 11.7 3.2 3.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_18 PF13238.6 OAG01701.1 - 0.063 13.8 0.1 0.34 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG01701.1 - 0.16 12.3 3.8 0.24 11.8 0.0 3.3 3 2 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 OAG01701.1 - 5.3 7.1 6.7 3.7 7.6 0.0 3.1 2 0 0 2 2 2 0 Helicase HerA, central domain Man-6-P_recep PF02157.15 OAG01702.1 - 3.8e-17 62.2 0.0 5.5e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 OAG01702.1 - 5.2e-10 39.6 0.0 5.3e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 OAG01702.1 - 5.6e-05 23.2 0.0 0.051 13.7 0.0 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 OAG01703.1 - 1.6e-160 534.6 7.9 1.9e-160 534.4 7.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OAG01703.1 - 0.00027 20.5 0.2 0.00085 18.9 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PBP PF01161.20 OAG01708.1 - 1.2e-12 48.3 0.0 1.6e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Lipoxygenase PF00305.19 OAG01709.1 - 8.1e-26 90.6 0.0 2.3e-25 89.2 0.0 1.6 2 0 0 2 2 2 1 Lipoxygenase DUF3185 PF11381.8 OAG01709.1 - 0.05 13.6 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Glyco_hydro_31 PF01055.26 OAG01710.1 - 3.7e-08 33.0 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF3614 PF12267.8 OAG01711.1 - 0.51 10.8 0.0 0.51 10.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) DUF3818 PF12825.7 OAG01712.1 - 1.7e-57 195.0 0.0 9.1e-35 120.3 0.1 3.0 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAG01712.1 - 2.4e-40 137.5 0.0 7.3e-40 136.0 0.0 1.9 2 0 0 2 2 2 1 PX-associated Metal_resist PF13801.6 OAG01712.1 - 0.022 14.9 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 Heavy-metal resistance DUF1409 PF07197.12 OAG01712.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) Alpha-amylase PF00128.24 OAG01715.1 - 2.3e-57 195.1 0.1 1.8e-55 188.9 0.1 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 OAG01715.1 - 3e-29 100.8 0.2 6.6e-29 99.7 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 OAG01715.1 - 0.005 17.1 0.2 0.018 15.3 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) GHL6 PF14871.6 OAG01715.1 - 0.015 15.5 0.0 0.056 13.6 0.0 2.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Cellulase PF00150.18 OAG01715.1 - 0.022 14.2 0.9 0.075 12.5 0.0 2.2 3 0 0 3 3 3 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.6 OAG01715.1 - 0.084 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain CBM_20 PF00686.19 OAG01716.1 - 3.6e-35 119.7 1.0 8.2e-35 118.6 1.0 1.6 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 OAG01716.1 - 1.5e-09 38.8 2.8 4.5e-09 37.3 2.8 1.8 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 OAG01716.1 - 0.0008 19.4 0.2 0.0079 16.2 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Toxin_17 PF08086.11 OAG01717.1 - 0.038 14.3 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Ergtoxin family RNA_pol_Rpc4 PF05132.14 OAG01717.1 - 0.17 12.3 12.0 0.33 11.4 12.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 SBP_bac_6 PF13343.6 OAG01718.1 - 7.1e-10 38.7 1.5 1.3e-09 37.9 1.5 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 OAG01718.1 - 0.00041 20.4 8.6 0.0013 18.7 8.6 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 OAG01718.1 - 0.0021 17.8 0.4 0.004 16.9 0.4 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein MFS_1 PF07690.16 OAG01719.1 - 1.7e-31 109.4 36.1 6.2e-31 107.6 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pec_lyase_C PF00544.19 OAG01720.1 - 9.2e-42 143.0 9.6 1.2e-41 142.6 9.6 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG01720.1 - 0.0016 18.3 10.7 0.0016 18.3 10.7 2.5 1 1 0 1 1 1 1 Right handed beta helix region Mito_carr PF00153.27 OAG01722.1 - 3.7e-66 219.1 4.9 5.9e-24 83.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_3 PF07859.13 OAG01723.1 - 1.4e-48 165.6 0.0 2e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG01723.1 - 3.6e-07 29.4 0.0 1.1e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 OAG01723.1 - 0.00016 20.5 0.0 0.0015 17.3 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 OAG01723.1 - 0.034 13.6 0.1 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OAG01723.1 - 0.04 12.8 0.0 0.069 12.0 0.0 1.3 1 1 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OAG01723.1 - 0.1 11.9 0.3 0.33 10.2 0.3 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 OAG01723.1 - 0.19 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.7 OAG01723.1 - 1.3 9.6 8.4 0.52 10.9 5.5 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family WD40 PF00400.32 OAG01724.1 - 2.7e-15 56.5 9.0 2.9e-05 24.7 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG01724.1 - 0.00037 20.7 1.7 8.9 6.7 0.0 4.7 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain AA_permease_2 PF13520.6 OAG01725.1 - 2.5e-65 221.0 49.8 3.1e-65 220.7 49.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG01725.1 - 2.7e-35 121.9 44.2 3.6e-35 121.5 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease Phage_holin_4_1 PF05105.12 OAG01725.1 - 2.4 8.3 13.0 0.35 11.0 3.8 3.2 2 1 0 2 2 2 0 Bacteriophage holin family Ras PF00071.22 OAG01726.1 - 1.9e-63 212.9 0.2 2.2e-63 212.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG01726.1 - 2.1e-35 121.5 0.2 3e-35 121.0 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG01726.1 - 3.1e-13 49.6 0.1 4e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG01726.1 - 8.4e-08 32.3 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG01726.1 - 9.5e-05 22.4 0.1 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAG01726.1 - 0.00026 20.6 0.1 0.001 18.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG01726.1 - 0.0004 19.8 0.1 0.00064 19.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OAG01726.1 - 0.0026 18.0 0.1 0.018 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 OAG01726.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OAG01726.1 - 0.013 15.6 0.2 0.039 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG01726.1 - 0.019 15.3 0.1 0.032 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OAG01726.1 - 0.024 15.1 0.2 0.039 14.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAG01726.1 - 0.027 14.2 0.1 0.061 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAG01726.1 - 0.038 13.4 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SpoIIID PF12116.8 OAG01726.1 - 0.092 12.8 0.1 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 OAG01726.1 - 0.1 12.2 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 OAG01726.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 OAG01726.1 - 0.13 12.1 0.7 0.15 11.9 0.7 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FAM176 PF14851.6 OAG01728.1 - 0.0029 17.3 3.0 0.0083 15.8 3.0 1.7 1 1 0 1 1 1 1 FAM176 family DUF4834 PF16118.5 OAG01728.1 - 0.008 17.1 1.7 0.37 11.8 1.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) DUF4190 PF13828.6 OAG01728.1 - 0.011 15.4 0.1 0.011 15.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) CDC45 PF02724.14 OAG01728.1 - 6.7 4.9 14.1 7.8 4.7 14.1 1.0 1 0 0 1 1 1 0 CDC45-like protein HET PF06985.11 OAG01730.1 - 1.1e-29 103.7 0.0 2e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_26 PF02156.15 OAG01730.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 DUF4003 PF13170.6 OAG01730.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Serinc PF03348.15 OAG01731.1 - 0.036 13.0 3.6 0.046 12.7 3.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) CorA PF01544.18 OAG01731.1 - 0.12 11.6 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AT_hook PF02178.19 OAG01732.1 - 0.0077 16.0 2.3 0.0077 16.0 2.3 3.0 3 0 0 3 3 3 1 AT hook motif SRI PF08236.11 OAG01733.1 - 2.7e-19 69.1 9.4 2.7e-19 69.1 9.4 2.1 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 OAG01733.1 - 6.1e-19 69.0 0.2 6.1e-19 69.0 0.2 2.8 2 2 0 2 2 2 1 SET domain AWS PF17907.1 OAG01733.1 - 2.9e-10 40.0 11.0 2.9e-10 40.0 11.0 2.4 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 OAG01733.1 - 3.9e-06 26.8 0.4 1.3e-05 25.1 0.4 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 OAG01733.1 - 0.00015 21.8 0.9 0.00034 20.6 0.9 1.7 1 0 0 1 1 1 1 WW domain Senescence PF06911.12 OAG01733.1 - 1.1 9.5 6.1 0.4 11.0 2.7 2.0 2 0 0 2 2 2 0 Senescence-associated protein Aminotran_3 PF00202.21 OAG01734.1 - 4.9e-119 397.6 0.0 5.6e-119 397.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG01734.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II APH PF01636.23 OAG01736.1 - 7.6e-09 35.8 0.0 1.6e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 OAG01736.1 - 0.058 12.6 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase STAC2_u1 PF16664.5 OAG01736.1 - 0.071 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Acyl-CoA_dh_1 PF00441.24 OAG01738.1 - 1.5e-37 129.1 0.3 2.5e-37 128.4 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG01738.1 - 2.5e-21 75.6 0.1 1.1e-20 73.6 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG01738.1 - 1.3e-11 44.9 0.0 2.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG01738.1 - 1.8e-06 28.6 0.1 1.5e-05 25.6 0.1 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain PH_BEACH PF14844.6 OAG01738.1 - 0.022 14.9 0.0 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH WD40 PF00400.32 OAG01739.1 - 8.7e-18 64.4 2.6 0.025 15.4 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF771 PF05595.11 OAG01739.1 - 0.0061 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF771) PQQ_3 PF13570.6 OAG01739.1 - 0.0094 16.4 0.0 2.2 8.9 0.0 3.8 5 0 0 5 5 5 1 PQQ-like domain WD40_like PF17005.5 OAG01739.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain XRCC4 PF06632.12 OAG01741.1 - 0.0013 17.7 16.9 0.0057 15.6 16.5 2.1 2 1 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.8 OAG01741.1 - 0.0055 16.9 1.5 0.011 15.9 1.5 1.5 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain tRNA-synt_1g PF09334.11 OAG01741.1 - 0.014 14.2 0.9 0.02 13.7 0.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Endostatin PF06482.11 OAG01741.1 - 1 8.8 4.2 1.4 8.3 4.2 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MFS_1 PF07690.16 OAG01742.1 - 9.5e-33 113.6 21.5 9.5e-33 113.6 21.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG01742.1 - 9e-07 28.5 2.1 9e-07 28.5 2.1 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2929 PF11151.8 OAG01742.1 - 2.6 8.4 6.0 4.4 7.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) zf-3CxxC PF13695.6 OAG01744.1 - 3.3e-17 62.8 0.7 4.3e-17 62.4 0.7 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 OAG01744.1 - 5.2 7.9 8.5 10 6.9 3.3 2.8 2 1 0 2 2 2 0 Zinc-binding domain zf_UBZ PF18439.1 OAG01745.1 - 0.00058 19.4 15.0 0.069 12.8 0.6 5.3 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger zf-Sec23_Sec24 PF04810.15 OAG01745.1 - 0.0017 18.3 0.6 16 5.7 0.0 3.9 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger zf-ACC PF17848.1 OAG01745.1 - 0.0029 17.6 1.1 0.064 13.3 0.1 2.8 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain zf_C2HC_14 PF18574.1 OAG01745.1 - 0.041 13.7 0.2 0.14 12.0 0.2 1.8 1 0 0 1 1 1 0 C2HC Zing finger domain Lar_restr_allev PF14354.6 OAG01745.1 - 0.086 13.2 7.8 1 9.8 0.3 4.3 3 2 1 4 4 4 0 Restriction alleviation protein Lar Terminase_GpA PF05876.12 OAG01745.1 - 1.1 7.7 4.1 0.44 9.1 0.3 2.0 1 1 1 3 3 3 0 Phage terminase large subunit (GpA) PHD_2 PF13831.6 OAG01745.1 - 6.7 6.4 7.2 21 4.8 0.1 4.1 4 0 0 4 4 4 0 PHD-finger WLM PF08325.10 OAG01746.1 - 1.7e-50 171.8 0.0 2.5e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 OAG01746.1 - 0.0041 16.9 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.17 OAG01746.1 - 0.016 15.2 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 ubiquitin PF00240.23 OAG01746.1 - 0.029 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family DUF3640 PF12342.8 OAG01746.1 - 0.62 9.9 2.7 1.9 8.3 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3640) LicD PF04991.13 OAG01747.1 - 1.2e-22 81.2 15.3 1.5e-17 64.5 2.1 2.8 2 1 1 3 3 3 2 LicD family TIP49 PF06068.13 OAG01749.1 - 2.5e-154 513.7 2.4 3.5e-154 513.2 2.4 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAG01749.1 - 1.3e-21 76.4 0.1 8.1e-21 73.9 0.1 2.4 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 OAG01749.1 - 1.8e-09 37.5 0.4 1.7e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 OAG01749.1 - 1.2e-07 32.2 0.4 0.00047 20.6 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG01749.1 - 7.4e-06 26.5 0.5 9.3e-05 22.9 0.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 OAG01749.1 - 8.8e-06 25.2 1.2 1.6e-05 24.4 1.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 OAG01749.1 - 0.0005 19.5 1.2 0.012 15.1 0.5 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG01749.1 - 0.0035 17.3 0.2 0.78 9.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OAG01749.1 - 0.0081 16.5 2.2 0.11 12.8 2.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG01749.1 - 0.01 16.1 0.0 0.51 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OAG01749.1 - 0.011 15.5 0.1 3.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 OAG01749.1 - 0.039 13.7 1.2 0.52 10.1 1.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG01749.1 - 0.082 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OAG01749.1 - 0.082 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LPP PF04728.13 OAG01750.1 - 0.018 15.4 0.6 0.018 15.4 0.6 8.4 9 1 1 10 10 10 0 Lipoprotein leucine-zipper ApoO PF09769.9 OAG01750.1 - 0.019 14.9 3.7 0.8 9.7 0.1 4.8 3 1 1 4 4 4 0 Apolipoprotein O GAS PF13851.6 OAG01750.1 - 0.046 13.1 0.2 0.046 13.1 0.2 6.8 3 3 2 6 6 6 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 OAG01750.1 - 0.048 13.7 0.1 0.048 13.7 0.1 9.4 3 3 7 11 11 11 0 Protein of unknown function (DUF1664) Thump_like PF18096.1 OAG01750.1 - 0.095 12.6 0.0 0.66 9.9 0.0 2.5 1 0 0 1 1 1 0 THUMP domain-like CEP209_CC5 PF16574.5 OAG01750.1 - 0.24 11.6 0.1 0.24 11.6 0.1 6.7 6 3 2 8 8 8 0 Coiled-coil region of centrosome protein CE290 YojJ PF10372.9 OAG01750.1 - 0.38 10.9 0.1 0.38 10.9 0.1 5.9 7 1 0 7 7 7 0 Bacterial membrane-spanning protein N-terminus Vac_Fusion PF02346.16 OAG01750.1 - 8 6.2 9.0 19 5.0 0.0 5.9 7 0 0 7 7 7 0 Chordopoxvirus multifunctional envelope protein A27 WW PF00397.26 OAG01752.1 - 4e-11 42.8 0.6 8.4e-11 41.8 0.6 1.6 1 0 0 1 1 1 1 WW domain F-box-like PF12937.7 OAG01753.1 - 0.025 14.5 1.1 0.062 13.2 0.0 2.3 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 OAG01753.1 - 0.14 12.7 8.6 0.11 13.0 0.7 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG01753.1 - 2.6 7.9 5.6 8.9 6.2 3.0 3.1 2 1 0 2 2 2 0 Leucine rich repeat FMO-like PF00743.19 OAG01754.1 - 2e-11 43.1 0.0 3.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG01754.1 - 1.3e-10 41.0 0.0 3.5e-09 36.3 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG01754.1 - 2.2e-10 40.3 0.0 3.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG01754.1 - 1.3e-07 31.7 0.1 5.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG01754.1 - 1.9e-06 27.7 0.1 0.16 11.5 0.0 3.4 2 1 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG01754.1 - 2e-06 27.9 0.1 7.6e-05 22.7 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG01754.1 - 2.6e-05 23.6 0.0 8.2e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 OAG01754.1 - 0.0026 17.1 0.0 0.0093 15.3 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 OAG01754.1 - 0.0029 16.8 0.5 6.8 5.7 0.1 3.5 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAG01754.1 - 0.0072 15.6 0.3 0.026 13.8 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 OAG01754.1 - 0.013 14.2 0.1 0.024 13.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAG01754.1 - 0.083 13.5 0.1 4.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG01754.1 - 0.14 11.3 0.1 0.42 9.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Na_H_Exchanger PF00999.21 OAG01755.1 - 3.3e-34 118.3 33.9 5.3e-34 117.6 33.9 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF5316 PF17247.2 OAG01755.1 - 4.3 7.4 8.6 7.4 6.7 0.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Glyco_hydro_61 PF03443.14 OAG01756.1 - 7.8e-57 192.5 0.3 9.8e-57 192.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF779 PF05610.11 OAG01756.1 - 0.071 13.4 0.0 8.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF779) Epimerase PF01370.21 OAG01757.1 - 6.1e-10 39.0 0.1 8e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG01757.1 - 6.3e-07 29.5 0.1 5.5e-06 26.4 0.0 2.4 1 1 1 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG01757.1 - 0.00031 20.3 0.1 0.0072 15.8 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG01757.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAG01757.1 - 0.0014 18.2 0.2 0.0094 15.5 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 OAG01757.1 - 0.0016 17.7 0.1 0.0049 16.1 0.0 1.9 3 0 0 3 3 3 1 Male sterility protein Semialdhyde_dh PF01118.24 OAG01757.1 - 0.0047 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG01757.1 - 0.0089 16.3 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAG01757.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 OAG01757.1 - 0.059 12.5 0.0 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain CAT_RBD PF03123.15 OAG01757.1 - 0.21 11.6 0.6 0.73 9.8 0.6 2.0 1 1 0 1 1 1 0 CAT RNA binding domain RNA12 PF10443.9 OAG01758.1 - 1.7e-173 577.5 0.4 4.8e-173 576.0 0.0 1.8 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 OAG01758.1 - 1e-05 25.2 0.0 3.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 OAG01758.1 - 0.00013 21.9 0.0 0.0006 19.8 0.0 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 OAG01758.1 - 0.00074 19.6 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) HD PF01966.22 OAG01761.1 - 8.4e-05 22.8 0.5 0.00017 21.8 0.5 1.6 1 1 0 1 1 1 1 HD domain PDEase_I PF00233.19 OAG01761.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase CCDC14 PF15254.6 OAG01763.1 - 1.4 7.5 5.6 1.6 7.2 5.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 MFS_1 PF07690.16 OAG01765.1 - 4.4e-41 141.0 33.4 4.4e-41 141.0 33.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG01765.1 - 1.2e-05 24.9 3.4 1.2e-05 24.9 3.4 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAG01765.1 - 0.051 11.8 5.3 0.015 13.6 2.2 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Strabismus PF06638.11 OAG01765.1 - 0.075 11.7 0.1 0.16 10.6 0.0 1.5 2 0 0 2 2 2 0 Strabismus protein QCR10 PF09796.9 OAG01766.1 - 2.6e-29 101.1 1.1 3.2e-29 100.8 1.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Proteasome PF00227.26 OAG01767.1 - 2.1e-54 183.9 0.1 2.8e-54 183.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG01767.1 - 2.2e-12 46.4 0.0 4.5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CHZ PF09649.10 OAG01768.1 - 1.2e-16 59.8 0.9 1.2e-16 59.8 0.9 2.3 3 0 0 3 3 3 1 Histone chaperone domain CHZ TMEM214 PF10151.9 OAG01769.1 - 0.2 10.1 0.1 0.24 9.8 0.1 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator GATase_2 PF00310.21 OAG01770.1 - 5.8e-180 598.5 0.0 7.8e-180 598.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 OAG01770.1 - 2.2e-156 520.6 0.0 5.1e-156 519.4 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 OAG01770.1 - 2.4e-113 378.2 0.0 3.4e-111 371.2 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OAG01770.1 - 1.6e-86 288.8 2.9 2.6e-86 288.1 2.9 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 OAG01770.1 - 1.9e-24 86.4 0.1 8.4e-24 84.3 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OAG01770.1 - 5.3e-21 74.5 0.1 1.1e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 OAG01770.1 - 7.4e-07 29.3 0.0 2.7e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG01770.1 - 1.5e-06 28.6 0.2 0.00085 19.8 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG01770.1 - 4.8e-06 26.1 2.7 0.079 12.2 0.0 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG01770.1 - 9.5e-06 25.4 0.6 0.059 12.9 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FMO-like PF00743.19 OAG01770.1 - 6.8e-05 21.5 0.2 0.06 11.8 0.0 3.0 4 0 0 4 4 4 2 Flavin-binding monooxygenase-like Amino_oxidase PF01593.24 OAG01770.1 - 0.00024 20.5 0.1 0.00066 19.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAG01770.1 - 0.00037 19.3 0.1 0.00037 19.3 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 OAG01770.1 - 0.0018 18.7 0.4 3.2 8.3 0.1 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OAG01770.1 - 0.0026 16.9 2.6 0.0036 16.4 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 OAG01770.1 - 0.0043 16.4 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG01770.1 - 0.0063 15.9 0.6 0.017 14.5 0.6 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG01770.1 - 0.013 14.9 0.3 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAG01770.1 - 0.043 13.0 0.1 0.13 11.5 0.1 1.7 1 0 0 1 1 1 0 Thi4 family FMN_dh PF01070.18 OAG01770.1 - 0.05 12.6 0.6 0.18 10.8 0.5 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.12 OAG01770.1 - 0.066 12.3 0.6 6.4 5.7 0.1 2.9 4 0 0 4 4 4 0 Lycopene cyclase protein PP2C_2 PF13672.6 OAG01770.1 - 0.092 12.4 0.8 0.24 11.0 0.8 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C MADF_DNA_bdg PF10545.9 OAG01770.1 - 0.14 12.5 0.9 0.34 11.3 0.9 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like 2-Hacid_dh_C PF02826.19 OAG01770.1 - 0.17 11.2 0.0 0.85 9.0 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 OAG01770.1 - 0.17 11.9 1.1 4.9 7.2 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.22 OAG01770.1 - 0.58 9.2 2.4 0.56 9.2 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 OAG01772.1 - 4.8e-29 101.4 48.8 3.2e-20 72.4 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 OAG01773.1 - 2.1e-51 175.1 2.2 2.5e-51 174.8 2.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme p450 PF00067.22 OAG01774.1 - 0.039 12.7 0.0 0.062 12.0 0.0 1.2 1 1 0 1 1 1 0 Cytochrome P450 VWD PF00094.25 OAG01774.1 - 0.095 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type D domain Use1 PF09753.9 OAG01776.1 - 0.0032 17.2 0.0 0.0033 17.2 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Aldo_ket_red PF00248.21 OAG01777.1 - 2.4e-51 174.7 0.0 2.7e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mcl1_mid PF12341.8 OAG01778.1 - 1e-93 313.9 0.0 5.9e-92 308.2 0.0 2.9 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 OAG01778.1 - 1.2e-15 57.5 1.2 8.1e-05 22.9 0.1 6.9 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG01778.1 - 2.1e-15 56.8 5.5 3.7e-05 24.4 0.1 7.3 9 0 0 9 9 7 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAG01778.1 - 2.1e-06 27.0 0.8 0.13 11.2 0.0 3.7 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 OAG01778.1 - 2.2e-05 23.7 0.5 6.6e-05 22.1 0.3 1.7 1 1 1 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 OAG01778.1 - 9.8e-05 21.0 1.7 0.0013 17.4 0.2 2.2 1 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 OAG01778.1 - 0.0018 18.1 2.6 5.5 7.1 0.0 4.4 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 OAG01778.1 - 0.0032 17.4 0.6 0.0075 16.2 0.6 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Frtz PF11768.8 OAG01778.1 - 0.0045 15.4 0.0 0.15 10.4 0.0 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 OAG01778.1 - 0.009 15.9 1.0 0.081 12.8 0.2 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG01778.1 - 0.051 12.9 0.1 0.22 10.8 0.0 2.2 3 0 0 3 3 3 0 WD40-like domain eIF_4EBP PF05456.11 OAG01778.1 - 1.3 9.0 2.9 2.6 8.0 0.1 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PQQ_3 PF13570.6 OAG01778.1 - 4.8 7.8 6.5 29 5.3 0.2 4.3 4 0 0 4 4 4 0 PQQ-like domain p450 PF00067.22 OAG01780.1 - 1.8e-57 195.1 0.0 2.3e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.13 OAG01781.1 - 1.2e-09 38.7 0.0 3e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 OAG01782.1 - 3e-09 36.2 0.4 5.1e-09 35.4 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.25 OAG01783.1 - 7.9e-16 58.2 0.0 7.3e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Reprolysin_2 PF13574.6 OAG01786.1 - 0.0042 17.0 0.4 0.28 11.0 0.0 2.3 1 1 1 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like PAF-AH_p_II PF03403.13 OAG01787.1 - 7.9e-08 31.2 0.0 0.0055 15.3 0.0 2.4 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 OAG01787.1 - 0.0035 18.0 0.3 0.01 16.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OAG01787.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Caps_synth PF05704.12 OAG01788.1 - 7.5e-13 48.5 0.0 2.1e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 OAG01788.1 - 4.7e-06 27.1 0.1 1.7e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif 2-Hacid_dh_C PF02826.19 OAG01790.1 - 5.6e-50 169.2 0.0 1e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG01790.1 - 1.4e-15 57.2 0.0 1.9e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PROCN PF08083.11 OAG01790.1 - 0.086 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain Tachystatin_A PF11406.8 OAG01791.1 - 0.027 14.5 1.4 0.22 11.6 0.0 3.2 4 1 1 5 5 5 0 Antimicrobial peptide tachystatin A OAD_beta PF03977.13 OAG01792.1 - 0.098 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit FH2 PF02181.23 OAG01793.1 - 8.9e-81 271.9 7.6 8.9e-81 271.9 7.6 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 OAG01793.1 - 2.6e-67 226.1 1.4 3.8e-67 225.5 0.1 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 OAG01793.1 - 2.5e-48 164.3 0.3 1.2e-47 162.0 0.2 2.2 1 1 1 2 2 2 1 Diaphanous FH3 Domain TRAF_BIRC3_bd PF16673.5 OAG01793.1 - 0.036 13.9 2.0 0.13 12.1 2.0 1.9 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Glyco_transf_7N PF13733.6 OAG01793.1 - 0.075 12.7 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 DUF2291 PF10054.9 OAG01793.1 - 0.16 11.7 1.2 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DUF1635 PF07795.11 OAG01793.1 - 1.6 8.5 8.2 10 5.9 7.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) peroxidase PF00141.23 OAG01794.1 - 3.2e-33 115.4 0.0 4.5e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 OAG01794.1 - 0.0002 21.2 0.0 0.00067 19.5 0.0 1.9 1 0 0 1 1 1 1 Fungal peroxidase extension region HET PF06985.11 OAG01796.1 - 1.2e-29 103.5 0.1 2.4e-29 102.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 OAG01796.1 - 0.025 14.6 0.9 0.089 12.9 0.4 2.3 2 0 0 2 2 2 0 WW domain ANF_receptor PF01094.28 OAG01796.1 - 0.23 10.5 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region RHD3 PF05879.12 OAG01797.1 - 0 1044.4 0.0 0 1044.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 OAG01797.1 - 5.1e-08 32.5 0.1 8.5e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 OAG01797.1 - 2.2e-05 24.6 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAG01797.1 - 0.00017 21.6 0.0 0.00049 20.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OAG01797.1 - 0.03 14.6 0.4 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 OAG01797.1 - 0.035 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin TPT PF03151.16 OAG01798.1 - 1e-56 192.5 8.2 1.2e-56 192.2 8.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OAG01798.1 - 2.4e-10 40.1 9.8 4.6e-10 39.2 9.8 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAG01798.1 - 3.2e-08 33.8 27.2 5.5e-05 23.4 12.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OAG01798.1 - 0.012 14.9 0.8 0.022 13.9 0.0 1.8 2 0 0 2 2 2 0 Nucleotide-sugar transporter Wzy_C PF04932.15 OAG01798.1 - 0.069 12.8 1.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 O-Antigen ligase RmuC PF02646.16 OAG01798.1 - 0.26 10.4 0.1 0.39 9.8 0.1 1.1 1 0 0 1 1 1 0 RmuC family PUF PF00806.19 OAG01800.1 - 2.2e-38 127.8 1.0 1.2e-06 27.9 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat Filament PF00038.21 OAG01800.1 - 0.09 12.3 2.9 0.14 11.7 2.9 1.2 1 0 0 1 1 1 0 Intermediate filament protein SGT1 PF07093.11 OAG01800.1 - 0.098 11.1 2.2 0.16 10.4 2.2 1.3 1 0 0 1 1 1 0 SGT1 protein Fucokinase PF07959.12 OAG01800.1 - 0.21 10.5 0.5 0.37 9.7 0.5 1.3 1 0 0 1 1 1 0 L-fucokinase UPF0242 PF06785.11 OAG01800.1 - 0.57 10.3 3.1 1 9.5 3.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 OAG01800.1 - 0.69 8.7 5.0 0.99 8.2 5.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HIG_1_N PF04588.13 OAG01801.1 - 2.4e-05 24.4 5.2 2.6e-05 24.3 0.6 2.3 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Eapp_C PF10238.9 OAG01801.1 - 3.8 7.6 12.4 22 5.1 12.4 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein Zip PF02535.22 OAG01801.1 - 6 6.0 5.7 15 4.7 5.6 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter AMP-binding PF00501.28 OAG01802.1 - 9.6e-88 294.6 0.0 1.2e-87 294.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DbpA PF03880.15 OAG01802.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 DbpA RNA binding domain DUF2561 PF10812.8 OAG01803.1 - 0.11 12.5 1.8 0.19 11.7 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) COesterase PF00135.28 OAG01804.1 - 4.5e-78 263.4 0.0 5.9e-71 239.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG01804.1 - 8.8e-10 38.8 0.1 1.4e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipoprotein_21 PF14041.6 OAG01804.1 - 0.1 12.7 0.0 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 LppP/LprE lipoprotein Ank_2 PF12796.7 OAG01806.1 - 1.8e-25 89.3 5.4 1.8e-09 38.1 0.1 4.9 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG01806.1 - 7.8e-18 64.6 2.9 5.4e-08 33.2 0.0 6.2 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG01806.1 - 1.3e-17 62.0 0.2 0.00021 21.5 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OAG01806.1 - 1.9e-17 63.1 4.1 6.2e-09 36.0 0.0 5.3 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG01806.1 - 2.2e-13 50.0 2.5 0.00052 20.4 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat GATase_7 PF13537.6 OAG01806.1 - 0.1 12.5 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain GLEYA PF10528.9 OAG01807.1 - 2.8e-18 66.1 0.8 2.8e-18 66.1 0.8 3.8 5 2 1 6 6 6 1 GLEYA domain Inhibitor_I36 PF03995.13 OAG01808.1 - 0.0036 17.2 0.4 0.037 14.0 0.2 2.0 1 1 1 2 2 2 1 Peptidase inhibitor family I36 Crystall_3 PF08964.10 OAG01808.1 - 0.07 13.3 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin Velvet PF11754.8 OAG01814.1 - 1.1e-49 169.6 0.0 2.2e-32 113.0 0.0 4.6 2 2 1 3 3 3 2 Velvet factor DUF3446 PF11928.8 OAG01818.1 - 1.5 9.1 7.1 0.41 11.0 0.9 2.3 1 1 1 2 2 2 0 Early growth response N-terminal domain Cys_Met_Meta_PP PF01053.20 OAG01819.1 - 2.8e-154 513.3 0.0 3.3e-154 513.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAG01819.1 - 2.4e-09 37.0 0.2 4e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OAG01819.1 - 2.6e-09 36.7 0.0 4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAG01819.1 - 2.8e-09 36.4 0.1 4.4e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG01819.1 - 6.7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 OAG01819.1 - 0.00051 18.7 0.1 0.00066 18.3 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 OAG01819.1 - 0.024 14.8 0.0 0.075 13.3 0.0 1.8 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 OAG01819.1 - 0.038 12.8 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Mid1 PF12929.7 OAG01821.1 - 3.1e-134 448.4 0.6 3.7e-134 448.1 0.6 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 OAG01821.1 - 0.00013 22.6 3.7 0.0059 17.2 0.8 2.5 2 0 0 2 2 2 2 Fz domain Spt4 PF06093.13 OAG01822.1 - 5.9e-33 112.8 0.6 7.2e-33 112.5 0.6 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Fer2_4 PF13510.6 OAG01822.1 - 0.018 15.0 2.6 0.62 10.2 0.2 2.9 2 1 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Coronavirus_5 PF05528.11 OAG01822.1 - 0.024 14.6 0.1 0.038 14.0 0.1 1.4 1 0 0 1 1 1 0 Coronavirus gene 5 protein Metallophos PF00149.28 OAG01823.1 - 5.4e-34 118.5 0.0 1e-33 117.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 OAG01823.1 - 3.8e-31 107.2 0.1 6.5e-31 106.5 0.1 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 OAG01823.1 - 0.00074 19.2 0.7 0.067 13.0 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG01823.1 - 0.0069 16.4 0.6 0.35 11.1 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG01823.1 - 0.0072 16.6 0.3 0.028 14.8 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG01823.1 - 0.013 15.1 0.3 0.031 14.0 0.1 1.7 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 OAG01823.1 - 0.17 12.1 0.1 0.6 10.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidohydro_1 PF01979.20 OAG01824.1 - 8.5e-24 84.5 0.0 1.5e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG01824.1 - 4.5e-13 49.5 0.4 2.7e-05 23.8 0.1 2.6 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 OAG01824.1 - 0.03 14.6 0.8 0.064 13.6 0.6 1.6 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain Peptidase_M20 PF01546.28 OAG01825.1 - 1.8e-32 112.7 0.1 2.5e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG01825.1 - 1.3e-05 25.1 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG01825.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 FAD_binding_3 PF01494.19 OAG01826.1 - 9.5e-65 219.1 0.0 1.2e-64 218.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG01826.1 - 1.7e-07 31.2 0.0 5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.12 OAG01826.1 - 4.8e-06 26.7 0.6 6.8e-05 23.0 0.3 2.5 2 1 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Trp_halogenase PF04820.14 OAG01826.1 - 2.8e-05 23.2 0.0 0.00012 21.0 0.0 1.8 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 OAG01826.1 - 0.002 18.1 0.0 0.0048 16.9 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG01826.1 - 0.01 16.1 0.0 0.032 14.4 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG01826.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 OAG01826.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG01826.1 - 0.08 11.6 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 OAG01826.1 - 0.09 12.1 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase WSC PF01822.19 OAG01827.1 - 1e-06 28.8 6.6 0.00081 19.5 0.1 2.3 2 0 0 2 2 2 2 WSC domain Fez1 PF06818.15 OAG01828.1 - 0.021 15.3 53.5 0.069 13.6 5.3 4.4 2 1 2 4 4 4 0 Fez1 DUF1624 PF07786.12 OAG01828.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) FlaC_arch PF05377.11 OAG01828.1 - 6.3 7.3 15.2 3.5 8.1 0.2 5.2 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Peptidase_M28 PF04389.17 OAG01829.1 - 5.6e-35 120.8 0.3 1.1e-34 119.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG01829.1 - 0.0029 17.3 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cyclase PF04199.13 OAG01831.1 - 2.7e-15 56.8 0.1 8.1e-15 55.3 0.1 1.6 1 1 0 1 1 1 1 Putative cyclase DHH PF01368.20 OAG01832.1 - 0.042 14.1 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 DHH family Glyco_hydro_61 PF03443.14 OAG01834.1 - 7.5e-50 169.7 0.1 9.2e-50 169.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Oxidored_q6 PF01058.22 OAG01837.1 - 8.2e-24 83.9 0.2 1e-23 83.6 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DEC-1_C PF04626.13 OAG01837.1 - 0.082 13.3 0.5 0.12 12.8 0.5 1.2 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Fungal_trans PF04082.18 OAG01838.1 - 1.2e-12 47.5 0.1 1.6e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01838.1 - 7.9e-09 35.5 7.2 1.8e-08 34.3 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC_2 PF13913.6 OAG01838.1 - 0.3 11.0 4.7 0.78 9.7 4.7 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 OAG01838.1 - 2.2 8.7 6.8 0.72 10.2 1.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAG01838.1 - 6.3 7.9 12.6 0.1 13.5 4.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger E1-E2_ATPase PF00122.20 OAG01839.1 - 1.8e-36 125.4 10.4 3.8e-36 124.3 1.3 3.6 3 1 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 OAG01839.1 - 1.1e-16 61.8 0.1 2.5e-16 60.6 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG01839.1 - 3.8e-13 48.9 0.0 3.8e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG01839.1 - 0.0049 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG01839.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Toprim_C_rpt PF13368.6 OAG01841.1 - 0.089 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Fascin PF06268.13 OAG01842.1 - 0.032 14.5 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Fascin domain p450 PF00067.22 OAG01843.1 - 2.2e-69 234.4 0.0 2.5e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1908 PF08926.11 OAG01844.1 - 4.6 6.2 10.4 2.4 7.2 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1908) CbiC PF02570.15 OAG01845.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Precorrin-8X methylmutase PBP PF01161.20 OAG01846.1 - 1.3e-18 67.6 0.0 1.7e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Acetyltransf_8 PF13523.6 OAG01848.1 - 1.4 8.6 3.6 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 OAG01850.1 - 3.2e-46 157.9 0.0 5.5e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG01850.1 - 8.3e-35 120.7 0.0 1.4e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG01850.1 - 7.2e-24 83.7 0.4 1.3e-23 82.9 0.4 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_C3 PF00548.20 OAG01854.1 - 0.12 12.3 1.5 0.19 11.6 0.5 1.8 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) Fez1 PF06818.15 OAG01854.1 - 0.27 11.7 46.0 0.067 13.6 9.0 4.3 1 1 3 4 4 4 0 Fez1 CAP PF00188.26 OAG01856.1 - 0.0038 18.1 0.5 0.016 16.1 0.5 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Pyr_redox_3 PF13738.6 OAG01857.1 - 1.7e-08 34.1 0.0 1.6e-07 30.9 0.0 2.4 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG01857.1 - 3.6e-08 33.0 0.0 9.2e-05 21.8 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG01857.1 - 2.2e-07 29.7 0.4 6.7e-06 24.8 0.0 3.0 3 1 1 4 4 4 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG01857.1 - 3.1e-05 24.1 0.1 0.00028 21.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG01857.1 - 9.4e-05 22.5 0.1 0.51 10.4 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 OAG01857.1 - 0.00039 19.7 0.0 0.038 13.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 OAG01857.1 - 0.011 15.1 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 OAG01857.1 - 0.032 13.6 0.1 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.19 OAG01857.1 - 0.091 12.0 0.2 0.41 9.9 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain RTA1 PF04479.13 OAG01858.1 - 1e-27 97.1 0.8 1.3e-27 96.8 0.8 1.0 1 0 0 1 1 1 1 RTA1 like protein Aspzincin_M35 PF14521.6 OAG01859.1 - 4.5e-12 46.7 0.5 8.2e-12 45.9 0.5 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 OAG01859.1 - 7.8e-08 31.6 0.1 1.1e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Epimerase PF01370.21 OAG01861.1 - 4.4e-08 32.9 0.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG01861.1 - 9.3e-06 25.0 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 OAG01861.1 - 0.0036 17.7 0.0 0.006 17.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG01861.1 - 0.0071 15.4 0.0 0.03 13.3 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG01861.1 - 0.094 12.1 0.0 1.1 8.5 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF953 PF06110.11 OAG01863.1 - 5.9e-14 51.7 0.0 7.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 OAG01863.1 - 0.00025 20.8 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Diedel PF13164.6 OAG01864.1 - 2.5 8.6 10.6 17 5.9 3.8 2.2 1 1 1 2 2 2 0 Diedel p450 PF00067.22 OAG01866.1 - 1.5e-44 152.5 0.0 1.8e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG01867.1 - 2.6e-29 102.3 41.3 2.1e-28 99.3 41.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG01867.1 - 3.8e-08 32.2 13.4 9.4e-08 30.9 13.3 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4235 PF14019.6 OAG01867.1 - 0.042 13.9 0.8 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Phage_holin_3_6 PF07332.11 OAG01867.1 - 0.11 12.5 0.1 0.11 12.5 0.1 4.7 3 2 2 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Methyltransf_2 PF00891.18 OAG01868.1 - 1.1e-20 73.9 0.0 1.6e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAG01868.1 - 0.068 13.9 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 OAG01869.1 - 1.4e-11 44.1 0.0 2.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 OAG01869.1 - 0.061 13.2 0.0 0.55 10.2 0.0 2.5 3 0 0 3 3 3 0 MarR family DUF2805 PF10985.8 OAG01869.1 - 0.085 13.2 0.1 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) DUF4118 PF13493.6 OAG01869.1 - 0.12 12.2 5.8 0.32 10.8 5.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Recombinase PF07508.13 OAG01869.1 - 0.17 12.3 0.0 0.76 10.2 0.0 1.9 2 0 0 2 2 2 0 Recombinase NmrA PF05368.13 OAG01870.1 - 3.8e-31 108.5 0.0 4.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG01870.1 - 4e-18 66.0 0.0 5.7e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG01870.1 - 0.017 14.6 0.0 0.044 13.2 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 OAG01871.1 - 2.2e-23 82.7 0.0 3.3e-23 82.2 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 OAG01872.1 - 1.4e-14 54.0 0.0 2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAG01872.1 - 0.0031 17.5 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Ad_Cy_reg PF16701.5 OAG01872.1 - 0.0049 16.6 0.1 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate cyclase regulatory domain TatD_DNase PF01026.21 OAG01872.1 - 0.051 12.9 0.1 0.77 9.1 0.0 2.2 1 1 1 2 2 2 0 TatD related DNase HTH_24 PF13412.6 OAG01872.1 - 0.17 11.5 0.0 0.46 10.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_2 PF00891.18 OAG01873.1 - 7e-25 87.6 0.0 1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAG01873.1 - 0.0011 19.6 0.0 0.0026 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG01873.1 - 0.022 15.4 0.0 0.049 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 OAG01873.1 - 0.023 14.2 0.0 0.055 13.0 0.0 1.7 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain MutL PF13941.6 OAG01873.1 - 0.031 12.9 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 MutL protein Methyltransf_12 PF08242.12 OAG01873.1 - 0.083 13.6 0.0 0.46 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 OAG01873.1 - 0.18 11.6 0.0 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase AMP-binding PF00501.28 OAG01874.1 - 6.2e-52 176.6 0.0 9.9e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 OAG01874.1 - 2.1e-24 86.9 0.5 2e-22 80.4 0.2 3.3 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 OAG01874.1 - 1.8e-07 31.4 0.0 4.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site GH3 PF03321.13 OAG01874.1 - 0.001 18.0 0.0 0.047 12.5 0.0 2.2 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Abhydrolase_1 PF00561.20 OAG01874.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Aminotran_1_2 PF00155.21 OAG01875.1 - 1.2e-47 162.8 0.0 1.5e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAG01875.1 - 0.0043 16.4 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Tospo_nucleocap PF01533.16 OAG01875.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Tospovirus nucleocapsid protein Alpha_L_fucos PF01120.17 OAG01876.1 - 1.3e-93 314.3 2.3 1.6e-93 313.9 2.3 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OAG01876.1 - 5.3e-10 39.7 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain SDA1 PF05285.12 OAG01877.1 - 2.1e-88 297.1 51.2 8.6e-88 295.1 43.3 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 OAG01877.1 - 2.3e-20 72.6 0.6 6.6e-20 71.2 0.1 2.1 2 0 0 2 2 2 1 NUC130/3NT domain MMS1_N PF10433.9 OAG01878.1 - 4.6e-127 424.6 0.0 1.3e-126 423.1 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAG01878.1 - 2.4e-87 293.3 0.0 1.4e-85 287.4 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region Arr-ms PF12120.8 OAG01878.1 - 0.1 12.8 0.0 0.52 10.5 0.0 2.2 1 0 0 1 1 1 0 Rifampin ADP-ribosyl transferase adh_short_C2 PF13561.6 OAG01883.1 - 2.2e-38 132.1 0.0 7.2e-38 130.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG01883.1 - 4e-34 117.8 0.0 7.4e-34 116.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG01883.1 - 0.035 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 OAG01883.1 - 0.046 13.2 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG01883.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AA_permease_2 PF13520.6 OAG01884.1 - 4.1e-47 161.0 57.5 5.5e-47 160.5 57.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG01884.1 - 2.2e-30 105.7 50.4 3e-30 105.3 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 OAG01884.1 - 0.18 11.7 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MMgT PF10270.9 OAG01884.1 - 0.27 11.6 0.5 4.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Membrane magnesium transporter CTV_P6 PF06706.11 OAG01884.1 - 0.35 10.6 5.1 2 8.2 0.1 3.4 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein p450 PF00067.22 OAG01885.1 - 6.8e-22 77.8 0.0 7.4e-21 74.4 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 OAG01886.1 - 4e-26 91.8 61.6 3e-16 59.3 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG01886.1 - 0.13 10.8 30.9 0.014 14.0 17.1 2.3 2 0 0 2 2 2 0 MFS/sugar transport protein Vps54_N PF10475.9 OAG01887.1 - 0.058 12.7 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex 4HBT_3 PF13622.6 OAG01889.1 - 6e-83 278.9 0.1 7.4e-83 278.6 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG01889.1 - 4.1e-26 91.4 0.1 3.5e-12 46.3 0.0 3.8 3 1 0 3 3 3 3 Acyl-CoA thioesterase Glyco_transf_41 PF13844.6 OAG01889.1 - 0.09 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 AMP-binding PF00501.28 OAG01890.1 - 1.3e-64 218.4 0.8 1.8e-35 122.4 0.0 3.9 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 OAG01890.1 - 5.9e-11 43.2 0.6 1.8e-10 41.6 0.6 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 OAG01890.1 - 0.0084 16.1 1.9 0.019 15.0 1.9 1.6 1 0 0 1 1 1 1 Gas vesicle protein G Corona_5a PF06336.11 OAG01891.1 - 0.049 13.6 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Coronavirus 5a protein Ferric_reduct PF01794.19 OAG01892.1 - 5.3e-22 78.3 3.9 5.3e-22 78.3 3.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG01892.1 - 2.1e-19 70.2 0.0 2e-10 41.0 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Fungal_trans PF04082.18 OAG01892.1 - 2e-09 36.9 0.1 4.6e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_8 PF08022.12 OAG01892.1 - 3.4e-05 23.9 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain COesterase PF00135.28 OAG01894.1 - 3.7e-90 303.3 0.1 1.1e-80 272.0 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG01894.1 - 1.2e-10 41.6 0.4 3.6e-10 40.1 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG01895.1 - 2e-90 304.1 0.0 2.5e-90 303.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG01895.1 - 0.0029 17.5 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG01895.1 - 0.0096 15.4 0.8 0.042 13.3 0.2 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family NRDE-2 PF08424.10 OAG01896.1 - 1.6e-81 273.9 1.4 3.6e-81 272.8 1.4 1.6 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference FAD-SLDH PF12318.8 OAG01896.1 - 0.1 12.7 1.7 0.24 11.5 1.7 1.6 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Mad3_BUB1_I PF08311.12 OAG01896.1 - 0.47 10.5 2.5 17 5.4 0.2 3.2 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 OAG01896.1 - 3.7 8.6 7.2 20 6.4 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat BP28CT PF08146.12 OAG01897.1 - 4.6e-30 104.5 8.8 1.1e-29 103.3 4.1 3.6 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 OAG01897.1 - 1.1e-20 74.2 3.8 1.1e-20 74.2 3.8 4.8 4 1 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 OAG01897.1 - 0.0021 18.4 18.5 2.4 8.6 0.2 8.9 7 2 2 10 10 10 1 HEAT repeats POC1 PF10450.9 OAG01897.1 - 0.02 13.8 0.1 0.043 12.8 0.1 1.4 1 0 0 1 1 1 0 POC1 chaperone HEAT_EZ PF13513.6 OAG01897.1 - 0.62 10.6 13.5 1.2 9.7 0.5 7.3 7 1 0 7 7 7 0 HEAT-like repeat UNC45-central PF11701.8 OAG01897.1 - 2.8 7.9 9.9 0.48 10.4 0.4 4.1 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central HEAT PF02985.22 OAG01897.1 - 7.8 7.0 22.3 3.3 8.2 0.1 8.7 10 0 0 10 10 10 0 HEAT repeat DUF2347 PF09804.9 OAG01898.1 - 8.2e-87 291.4 0.0 1.1e-86 290.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 OAG01898.1 - 1.7e-33 116.5 13.0 2.2e-13 50.7 1.2 3.5 1 1 2 3 3 3 3 Domain of unknown function (DUF4484) SPA PF08616.10 OAG01898.1 - 0.0005 20.0 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 Stabilization of polarity axis HMGL-like PF00682.19 OAG01899.1 - 4.2e-81 272.4 0.0 7.5e-81 271.6 0.0 1.4 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 OAG01899.1 - 3.8e-24 85.1 0.1 9.7e-24 83.8 0.1 1.7 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Pyridoxal_deC PF00282.19 OAG01900.1 - 1.7e-71 240.9 0.0 2e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAG01900.1 - 0.00025 20.1 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Fungal_trans PF04082.18 OAG01902.1 - 6.8e-17 61.4 0.1 1.1e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01902.1 - 1.7e-07 31.2 14.1 3.4e-07 30.3 14.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A_deaminase PF00962.22 OAG01904.1 - 4.5e-78 262.9 0.0 5.1e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 OAG01904.1 - 0.0039 16.6 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family PS_Dcarbxylase PF02666.15 OAG01906.1 - 3.1e-77 258.6 0.0 7.4e-77 257.4 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2407 PF10302.9 OAG01907.1 - 4.3e-05 24.0 0.8 0.00015 22.3 0.0 2.3 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAG01907.1 - 0.0051 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family MFS_1 PF07690.16 OAG01908.1 - 1.5e-36 126.0 22.0 1.5e-36 126.0 22.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4079 PF13301.6 OAG01908.1 - 1.5 8.9 5.2 3 8.0 0.1 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) CoA_trans PF01144.23 OAG01909.1 - 5e-98 326.8 3.2 4.7e-61 205.9 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 OAG01909.1 - 0.00026 20.9 1.8 0.0013 18.7 0.1 2.1 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 OAG01909.1 - 0.01 14.2 0.0 0.018 13.4 0.0 1.3 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Zn_clus PF00172.18 OAG01910.1 - 1.7e-05 24.8 6.3 1.7e-05 24.8 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NfI_DNAbd_pre-N PF10524.9 OAG01910.1 - 0.16 11.9 0.8 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus Acyl_transf_3 PF01757.22 OAG01911.1 - 1.1e-06 27.9 41.0 2.3e-06 26.9 41.0 1.5 1 0 0 1 1 1 1 Acyltransferase family Glyco_trans_2_3 PF13632.6 OAG01912.1 - 1.1e-16 61.4 10.7 1.1e-16 61.4 10.7 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG01912.1 - 1.7e-16 60.8 0.0 2.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG01912.1 - 3.2e-05 23.5 0.0 7.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG01912.1 - 0.0006 19.7 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 HET PF06985.11 OAG01914.1 - 4.2e-19 69.3 0.2 8.6e-19 68.3 0.2 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 OAG01915.1 - 1.7e-51 175.4 0.0 2.2e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PreAtp-grasp PF18604.1 OAG01916.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Pre ATP-grasp domain SNF2_N PF00176.23 OAG01916.1 - 0.15 10.7 0.1 0.24 10.1 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain PAG PF15347.6 OAG01917.1 - 0.063 12.3 0.6 0.093 11.7 0.6 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Beta-prism_lec PF16458.5 OAG01917.1 - 0.12 12.3 2.7 0.17 11.8 1.2 2.0 2 0 0 2 2 2 0 Beta-prism lectin Zn_clus PF00172.18 OAG01919.1 - 6.9e-09 35.7 8.0 1.3e-08 34.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG01919.1 - 4e-07 29.2 1.5 4e-07 29.2 1.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_transf_90 PF05686.12 OAG01920.1 - 1.3e-15 57.2 0.2 1.1e-10 41.1 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 90 MFS_1 PF07690.16 OAG01921.1 - 1.1e-32 113.4 20.4 1.1e-32 113.4 20.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG01921.1 - 2.4e-13 49.8 2.6 2.4e-13 49.8 2.6 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter PTR2 PF00854.21 OAG01921.1 - 0.011 14.7 1.6 0.018 13.9 1.6 1.4 1 0 0 1 1 1 0 POT family UL41A PF17591.2 OAG01921.1 - 0.17 12.0 0.9 0.88 9.7 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus UL41A Pyr_redox_3 PF13738.6 OAG01922.1 - 3.9e-11 42.8 0.0 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG01922.1 - 6.9e-10 38.6 0.0 4.9e-07 29.3 0.0 2.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG01922.1 - 2.4e-06 26.3 0.0 0.00053 18.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG01922.1 - 8.6e-06 25.9 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG01922.1 - 0.0001 21.6 0.0 0.0022 17.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAG01922.1 - 0.0032 16.7 0.1 0.011 15.0 0.0 1.7 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 OAG01922.1 - 0.0038 16.9 0.1 0.24 10.9 0.0 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG01922.1 - 0.015 15.9 0.0 0.57 10.8 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG01922.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Cation_efflux PF01545.21 OAG01923.1 - 8e-18 64.9 7.6 1e-17 64.6 7.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG01923.1 - 2.9e-10 40.1 0.6 1.5e-09 37.9 0.2 2.4 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter APH PF01636.23 OAG01924.1 - 1.8e-09 37.9 0.6 3.5e-09 36.9 0.6 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG01924.1 - 0.0071 15.2 0.0 0.0098 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAG01924.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 OAG01924.1 - 0.25 10.6 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Hist_deacetyl PF00850.19 OAG01925.1 - 7.4e-54 183.3 0.1 1.3e-53 182.5 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain PAP2 PF01569.21 OAG01926.1 - 2.3e-07 30.6 0.0 4.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily NMO PF03060.15 OAG01927.1 - 1.3e-55 189.1 0.2 1.8e-55 188.7 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG01927.1 - 3.6e-11 42.6 1.3 7.6e-11 41.6 1.3 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG01927.1 - 2.7e-06 26.7 2.4 4.5e-06 25.9 2.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG01927.1 - 0.00073 18.8 1.1 0.0012 18.1 1.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 OAG01927.1 - 0.023 13.9 0.6 0.04 13.1 0.6 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 OAG01927.1 - 0.043 13.3 0.1 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Aldolase_II PF00596.21 OAG01928.1 - 2.6e-46 157.9 0.0 3.3e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_C41 PF05417.11 OAG01928.1 - 0.12 12.2 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Hepatitis E cysteine protease SKG6 PF08693.10 OAG01929.1 - 1.4e-08 34.0 0.0 2.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pex14_N PF04695.13 OAG01929.1 - 0.0047 17.6 2.2 0.0079 16.9 2.2 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Syndecan PF01034.20 OAG01929.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 OAG01929.1 - 0.26 11.2 1.8 0.71 9.8 1.9 1.7 1 1 0 1 1 1 0 TMEM154 protein family zf-Mss51 PF13824.6 OAG01930.1 - 1.5e-26 92.2 11.7 4.6e-26 90.7 11.7 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DTW PF03942.15 OAG01930.1 - 0.042 13.5 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 DTW domain zf-MYND PF01753.18 OAG01930.1 - 0.19 11.9 6.1 0.068 13.3 2.6 2.1 2 0 0 2 2 2 0 MYND finger Sugar_tr PF00083.24 OAG01932.1 - 8e-76 255.7 22.6 9.3e-76 255.5 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01932.1 - 1.2e-14 54.0 42.2 1.1e-09 37.7 15.4 2.8 1 1 1 3 3 3 2 Major Facilitator Superfamily DUF3792 PF12670.7 OAG01932.1 - 0.47 10.6 23.1 1.5 9.0 6.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) MFS_1_like PF12832.7 OAG01932.1 - 3.1 6.6 15.2 0.026 13.4 5.9 2.2 2 1 0 3 3 3 0 MFS_1 like family Sugar_tr PF00083.24 OAG01933.1 - 8.8e-77 258.9 27.4 1e-76 258.7 27.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01933.1 - 1.2e-17 63.9 32.2 1.2e-17 63.9 32.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRIF-NTD PF17798.1 OAG01933.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 TRIF N-terminal domain DUF1996 PF09362.10 OAG01934.1 - 1.1e-72 244.9 4.3 1.3e-72 244.6 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Phage_Orf51 PF06194.11 OAG01934.1 - 0.038 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 Ferritin_2 PF13668.6 OAG01935.1 - 0.00028 21.1 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Zn_clus PF00172.18 OAG01937.1 - 2.5e-07 30.7 7.2 4.7e-07 29.8 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG01937.1 - 8.6e-05 21.5 0.1 0.00047 19.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2306 PF10067.9 OAG01938.1 - 1.6e-14 54.3 11.7 3.5e-14 53.2 11.7 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 OAG01938.1 - 0.0094 16.2 6.8 1.4 9.2 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF420) adh_short PF00106.25 OAG01939.1 - 1.2e-18 67.3 0.0 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01939.1 - 6.8e-12 45.4 0.0 9.6e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG01939.1 - 0.00011 22.1 0.0 0.00041 20.3 0.0 1.8 1 1 0 1 1 1 1 KR domain DUF1996 PF09362.10 OAG01940.1 - 8.7e-81 271.3 1.0 1.2e-80 270.9 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Peptidase_S15 PF02129.18 OAG01941.1 - 5.3e-62 209.8 0.2 8e-62 209.3 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG01941.1 - 5.3e-47 160.6 0.0 7.2e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_1 PF00561.20 OAG01941.1 - 2.2e-09 37.3 0.1 8.2e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG01941.1 - 2.4e-07 30.3 0.0 4.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG01941.1 - 4.4e-07 29.6 0.2 9.1e-07 28.6 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG01941.1 - 2.8e-05 24.8 0.0 7e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OAG01941.1 - 0.016 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 OAG01941.1 - 0.04 13.8 0.1 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 OAG01942.1 - 8.7e-28 97.4 24.2 4.7e-14 52.1 6.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG01942.1 - 7.2e-20 71.2 35.5 1.7e-11 43.7 9.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 OAG01942.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like p450 PF00067.22 OAG01943.1 - 1.6e-42 145.8 0.0 3.2e-42 144.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF5554 PF17709.1 OAG01944.1 - 0.14 12.3 0.9 2.1 8.5 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5554) adh_short PF00106.25 OAG01946.1 - 6.3e-18 64.9 0.0 2e-13 50.3 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG01946.1 - 1.4e-12 47.7 0.0 2.5e-10 40.3 0.0 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG01946.1 - 6e-06 26.3 0.0 9.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG01946.1 - 0.0048 16.4 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 OAG01946.1 - 0.086 12.2 0.0 0.3 10.5 0.0 1.9 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme FinO_N PF12602.8 OAG01946.1 - 0.1 12.9 0.6 13 6.2 0.1 2.4 2 0 0 2 2 2 0 Fertility inhibition protein N terminal IlvB_leader PF08049.11 OAG01946.1 - 0.13 12.2 3.1 0.63 10.0 0.7 2.6 2 0 0 2 2 2 0 IlvB leader peptide IBR PF01485.21 OAG01947.1 - 2.2e-05 24.6 4.3 2.2e-05 24.6 4.3 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain CUE PF02845.16 OAG01947.1 - 0.025 14.3 0.2 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 CUE domain FbpA PF05833.11 OAG01947.1 - 0.12 11.1 0.1 0.33 9.6 0.1 1.7 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) zf-C2H2 PF00096.26 OAG01949.1 - 6.8e-10 38.8 18.8 0.0002 21.6 2.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG01949.1 - 9.7e-08 32.2 20.5 0.0035 18.0 1.5 4.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG01949.1 - 0.00034 20.9 2.7 0.00034 20.9 2.7 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 OAG01949.1 - 1.2 9.2 4.2 7.4 6.7 0.5 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger BTB PF00651.31 OAG01950.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Cu-oxidase_3 PF07732.15 OAG01952.1 - 1.1e-28 99.6 3.0 1.3e-28 99.4 0.1 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG01952.1 - 4.4e-28 98.4 0.1 1.6e-25 90.1 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG01952.1 - 2.5e-21 75.8 10.5 1.8e-17 63.3 3.4 4.3 3 2 0 3 3 3 2 Multicopper oxidase Thg1C PF14413.6 OAG01952.1 - 0.11 12.7 0.1 0.52 10.5 0.0 2.0 1 1 0 1 1 1 0 Thg1 C terminal domain GFA PF04828.14 OAG01953.1 - 1.9e-19 69.8 4.1 9.4e-12 45.1 0.1 3.4 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Sugar_tr PF00083.24 OAG01956.1 - 1.7e-25 89.9 1.2 3.2e-25 88.9 1.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG01956.1 - 2.9e-06 26.4 1.6 4.2e-06 25.9 1.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG01956.1 - 0.00081 18.0 0.7 0.0013 17.3 0.1 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein Sulfatase PF00884.23 OAG01957.1 - 2e-77 260.6 0.0 2.7e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OAG01957.1 - 9.6e-05 22.6 0.0 0.00032 20.9 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 OAG01957.1 - 0.0013 19.4 0.0 0.017 15.8 0.0 2.3 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 OAG01957.1 - 0.0091 14.6 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) MFS_1 PF07690.16 OAG01960.1 - 3.6e-33 115.0 45.0 3.6e-33 115.0 45.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG01960.1 - 9.8e-10 37.9 13.9 9.8e-10 37.9 13.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter VirB8 PF04335.13 OAG01960.1 - 0.28 11.0 1.5 0.57 10.0 0.2 2.1 2 0 0 2 2 2 0 VirB8 protein DUF3796 PF12676.7 OAG01960.1 - 0.62 10.5 0.1 0.62 10.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) ADH_N PF08240.12 OAG01962.1 - 1e-08 35.0 0.1 4e-08 33.1 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG01962.1 - 1.7e-07 31.3 0.0 3.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG01962.1 - 0.0079 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Eno-Rase_NADH_b PF12242.8 OAG01962.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2314 PF10077.9 OAG01962.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Fungal_trans PF04082.18 OAG01963.1 - 2.8e-15 56.1 0.1 4.8e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01963.1 - 1.8e-08 34.4 9.2 3.4e-08 33.5 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5089 PF17002.5 OAG01963.1 - 0.41 10.5 2.9 0.18 11.7 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) ERAP1_C PF11838.8 OAG01964.1 - 0.0094 15.5 0.0 2.6 7.5 0.0 2.0 2 0 0 2 2 2 2 ERAP1-like C-terminal domain SH3_9 PF14604.6 OAG01965.1 - 6.5e-10 38.7 0.2 1.3e-09 37.8 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG01965.1 - 2.1e-08 33.6 0.1 4.5e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG01965.1 - 4.4e-06 26.3 0.0 8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DNA_pol_phi PF04931.13 OAG01965.1 - 2.2 6.3 10.1 3.6 5.6 10.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi RPAP2_Rtr1 PF04181.13 OAG01966.1 - 2.6e-22 78.9 0.0 4.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF688 PF05097.12 OAG01966.1 - 0.00079 18.7 1.3 0.0016 17.7 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF688) zf-UBP PF02148.19 OAG01966.1 - 0.089 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Mit_ribos_Mrp51 PF11709.8 OAG01967.1 - 3.5e-106 355.9 1.7 4.7e-106 355.5 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit EthD PF07110.11 OAG01967.1 - 0.063 14.4 0.1 0.17 13.0 0.1 1.8 1 0 0 1 1 1 0 EthD domain APG6_N PF17675.1 OAG01968.1 - 0.077 13.5 0.7 0.11 13.1 0.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Mitofilin PF09731.9 OAG01970.1 - 0.046 12.6 34.5 0.11 11.3 34.5 1.6 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Lant_dehydr_C PF14028.6 OAG01970.1 - 2.2 7.7 14.9 5.9 6.3 15.0 1.7 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term HET PF06985.11 OAG01971.1 - 3.2e-26 92.4 3.8 1.1e-25 90.7 3.8 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LapA_dom PF06305.11 OAG01972.1 - 0.028 14.2 0.2 0.051 13.4 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain LSM PF01423.22 OAG01973.1 - 1.3e-18 66.4 0.2 1.6e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 OAG01973.1 - 0.0016 18.9 10.3 0.0024 18.4 10.3 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Zn_clus PF00172.18 OAG01974.1 - 0.041 14.0 9.9 0.1 12.8 9.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SfLAP PF11139.8 OAG01975.1 - 0.016 14.6 2.3 3 7.2 0.0 4.7 4 1 0 4 4 4 0 Sap, sulfolipid-1-addressing protein Macoilin PF09726.9 OAG01975.1 - 2.7 6.5 12.3 5.8 5.4 12.3 1.5 1 0 0 1 1 1 0 Macoilin family zf-C2H2 PF00096.26 OAG01978.1 - 2.7e-14 52.7 8.8 2.1e-07 31.0 3.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG01978.1 - 3.3e-09 36.8 8.8 4.3e-05 24.0 2.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG01978.1 - 2e-07 31.1 13.7 6.7e-06 26.3 3.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG01978.1 - 2.1e-07 31.0 3.8 0.00018 21.7 1.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG01978.1 - 0.018 15.4 2.8 0.35 11.3 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 OAG01978.1 - 0.028 14.4 2.0 3.8 7.6 0.5 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 OAG01978.1 - 0.066 13.6 1.6 0.24 11.7 0.5 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 OAG01978.1 - 0.096 12.6 0.5 9.4 6.2 0.0 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 OAG01978.1 - 0.14 12.2 6.5 1.5 8.9 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OAG01978.1 - 0.2 11.4 3.2 0.22 11.3 1.1 2.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain CAAP1 PF15335.6 OAG01979.1 - 0.42 11.2 1.6 0.61 10.7 0.3 1.9 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Cu-oxidase_2 PF07731.14 OAG01980.1 - 4.6e-49 165.7 8.5 1.4e-42 144.7 1.4 3.6 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG01980.1 - 5.9e-44 148.9 11.6 6.9e-43 145.5 1.4 4.3 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG01980.1 - 2.7e-42 144.6 3.8 4.8e-35 121.0 0.2 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 OAG01980.1 - 1.9e-05 24.7 0.0 2.1 8.5 0.0 4.2 4 1 0 4 4 4 3 Cupredoxin-like domain Monooxygenase_B PF04744.12 OAG01980.1 - 0.014 14.3 0.4 0.047 12.5 0.1 1.9 2 0 0 2 2 2 0 Monooxygenase subunit B protein FTR1 PF03239.14 OAG01981.1 - 3.6e-86 289.1 8.4 4.5e-86 288.8 8.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3021 PF11457.8 OAG01981.1 - 0.11 12.9 12.2 2.3 8.6 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) DUF4173 PF13777.6 OAG01981.1 - 0.17 11.3 4.9 0.14 11.6 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) adh_short_C2 PF13561.6 OAG01982.1 - 5.6e-57 193.0 4.5 6.7e-57 192.7 4.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG01982.1 - 1.8e-55 187.5 5.2 2.3e-55 187.1 5.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG01982.1 - 1e-16 61.4 2.3 1.4e-16 60.9 2.3 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG01982.1 - 0.0001 21.8 0.3 0.00023 20.7 0.1 1.6 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG01982.1 - 0.00027 20.5 1.1 0.001 18.6 0.2 2.2 1 1 2 3 3 3 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG01982.1 - 0.0031 17.1 2.2 0.0069 16.0 0.2 2.3 2 1 1 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.6 OAG01982.1 - 0.021 14.7 3.1 0.033 14.1 3.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding LytR_C PF13399.6 OAG01982.1 - 0.06 14.3 0.8 0.37 11.8 0.1 2.1 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator GMC_oxred_N PF00732.19 OAG01984.1 - 1.9e-50 172.0 0.0 2.4e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG01984.1 - 4.3e-34 118.1 0.0 1.1e-33 116.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG01984.1 - 3.2e-08 33.1 0.6 0.0015 17.7 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 OAG01984.1 - 2.8e-06 26.8 0.2 0.039 13.2 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG01984.1 - 5.1e-06 26.3 0.9 0.00015 21.4 0.8 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG01984.1 - 0.00071 18.7 0.1 0.0012 17.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG01984.1 - 0.002 17.4 0.3 0.007 15.6 0.6 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.23 OAG01984.1 - 0.0038 17.0 0.3 0.53 10.3 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif NAD_binding_8 PF13450.6 OAG01984.1 - 0.0064 16.7 1.6 0.021 15.1 1.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG01984.1 - 0.15 11.3 0.2 0.29 10.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAG01984.1 - 0.21 10.2 0.5 0.44 9.2 0.5 1.5 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.16 OAG01985.1 - 2.4e-28 99.1 46.6 2.4e-28 99.1 46.6 3.0 2 1 1 3 3 3 1 Major Facilitator Superfamily Peptidase_M56 PF05569.11 OAG01985.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 BlaR1 peptidase M56 NADH_dh_m_C1 PF15088.6 OAG01985.1 - 0.12 12.0 0.1 0.37 10.4 0.1 1.8 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial LRR_11 PF18831.1 OAG01985.1 - 6.9 6.3 7.8 4.3 7.0 0.1 3.3 3 0 0 3 3 3 0 Leucine-rich repeat ADH_N PF08240.12 OAG01986.1 - 3.9e-24 84.6 3.2 7.2e-24 83.8 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG01986.1 - 8.7e-14 51.6 0.1 1.4e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG01986.1 - 0.0059 16.0 0.2 0.0095 15.3 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 OAG01986.1 - 0.0089 15.8 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 OAG01986.1 - 0.032 15.3 0.0 0.091 13.8 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF1450 PF07293.11 OAG01986.1 - 1.6 8.6 3.7 22 4.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Fungal_trans PF04082.18 OAG01987.1 - 5.9e-14 51.7 0.5 8.8e-14 51.2 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG01987.1 - 8.2e-05 22.6 11.7 8.2e-05 22.6 11.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 OAG01987.1 - 0.0012 18.6 4.3 0.003 17.4 4.3 1.7 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat AMP-binding PF00501.28 OAG01988.1 - 7.3e-37 127.0 0.1 1.3e-36 126.2 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAG01988.1 - 7.4e-36 123.6 0.0 1.2e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAG01988.1 - 4e-14 52.7 0.0 7.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG01988.1 - 3.5e-09 36.9 0.1 1.3e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 OAG01988.1 - 0.00016 20.9 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAG01988.1 - 0.0003 20.3 0.0 0.00059 19.3 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG01988.1 - 0.11 12.4 0.1 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 KR domain Aldo_ket_red PF00248.21 OAG01989.1 - 8.4e-74 248.4 0.0 9.7e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_3 PF01596.17 OAG01990.1 - 1.1e-31 109.7 0.0 1.4e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAG01990.1 - 1.9e-15 57.8 0.0 4.1e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG01990.1 - 5.8e-09 35.9 0.0 8.8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG01990.1 - 2.3e-08 34.0 0.1 4.3e-08 33.2 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 OAG01990.1 - 3.6e-08 33.3 0.0 5.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 OAG01990.1 - 3.1e-07 31.0 0.0 5.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG01990.1 - 2.2e-05 25.0 0.0 5.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG01990.1 - 0.00081 19.3 0.0 0.0018 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG01990.1 - 0.0014 19.4 0.0 0.0031 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAG01990.1 - 0.0064 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG01990.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG01990.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 OAG01990.1 - 0.026 14.0 0.0 0.064 12.6 0.0 1.7 2 0 0 2 2 2 0 Spermine/spermidine synthase domain CmcI PF04989.12 OAG01990.1 - 0.037 13.7 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase UPF0020 PF01170.18 OAG01990.1 - 0.039 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 NAD_binding_4 PF07993.12 OAG01991.1 - 3.2e-32 111.7 0.0 4.8e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG01991.1 - 1.8e-24 86.1 0.0 3e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAG01991.1 - 2e-12 47.1 0.0 7.3e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG01991.1 - 9.3e-06 25.3 0.0 2.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG01991.1 - 6.7e-05 22.9 0.0 0.00079 19.4 0.0 2.2 1 1 0 1 1 1 1 KR domain PP-binding PF00550.25 OAG01991.1 - 0.00025 21.3 0.0 0.0019 18.5 0.0 2.5 2 1 0 2 2 2 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 OAG01991.1 - 0.0029 16.8 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG01991.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG01991.1 - 0.036 13.2 0.0 7.2 5.6 0.0 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain STE2 PF02116.15 OAG01992.1 - 3.8 6.7 17.8 17 4.6 15.4 2.5 1 1 1 2 2 2 0 Fungal pheromone mating factor STE2 GPCR An_peroxidase PF03098.15 OAG01994.1 - 2.6e-36 125.3 0.0 7.1e-22 77.7 0.0 3.4 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 OAG01994.1 - 3.3e-13 49.2 0.0 2.3e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 Sugar_tr PF00083.24 OAG01995.1 - 6.8e-34 117.5 14.3 7.4e-24 84.4 0.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG01995.1 - 3.1e-19 69.1 21.1 9.9e-17 60.9 2.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OFeT_1 PF16955.5 OAG01995.1 - 0.09 12.5 5.3 0.15 11.8 1.7 2.4 2 0 0 2 2 2 0 Ferrous iron uptake permease, iron-lead transporter Peptidase_S8 PF00082.22 OAG01996.1 - 1.2e-17 64.1 0.0 2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_S41 PF03572.18 OAG01998.1 - 1e-07 31.7 0.0 3.4e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 Bromodomain PF00439.25 OAG01998.1 - 0.026 14.6 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 Bromodomain HET PF06985.11 OAG01999.1 - 2.1e-22 80.0 0.0 4.2e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 OAG01999.1 - 6.5e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG01999.1 - 6.5e-06 26.5 0.0 1.9e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG01999.1 - 0.0022 18.4 0.0 0.0063 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAG01999.1 - 0.011 15.8 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OAG01999.1 - 0.034 13.9 0.2 0.14 11.9 0.1 2.1 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 OAG01999.1 - 0.043 13.2 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 OAG01999.1 - 0.075 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAG01999.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.29 OAG01999.1 - 0.19 12.2 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 OAG02000.1 - 2e-43 148.2 0.0 2.5e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02000.1 - 2.2e-30 106.0 0.0 2.9e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG02000.1 - 2.3e-05 24.4 0.0 5.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG02000.1 - 0.00072 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAG02000.1 - 0.00078 18.9 0.0 0.061 12.7 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAG02000.1 - 0.0038 16.7 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG02000.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 OAG02000.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF3425 PF11905.8 OAG02001.1 - 9e-20 70.9 0.2 1.9e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Glyco_hydro_76 PF03663.14 OAG02003.1 - 8e-91 305.3 10.7 9.1e-91 305.1 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG02003.1 - 0.0003 20.0 4.6 0.034 13.2 0.2 3.3 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 DUF4987 PF16377.5 OAG02003.1 - 0.0074 16.5 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function SGL PF08450.12 OAG02004.1 - 5.2e-25 88.4 0.1 1.2e-24 87.3 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAG02004.1 - 6.2e-05 23.1 0.0 0.00028 21.0 0.0 2.0 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 OAG02004.1 - 0.00098 19.2 0.0 0.017 15.2 0.0 2.7 2 1 0 2 2 2 1 Strictosidine synthase HMG-CoA_red PF00368.18 OAG02005.1 - 5.3e-139 463.3 6.5 7.3e-139 462.9 6.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 OAG02005.1 - 2.7e-42 144.3 0.3 4.1e-42 143.7 0.3 1.3 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 OAG02005.1 - 3.5e-18 65.9 3.6 6.9e-18 65.0 3.6 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAG02005.1 - 8.7e-08 30.7 4.6 8.7e-08 30.7 4.6 1.6 2 0 0 2 2 2 1 Patched family DUF3605 PF12239.8 OAG02006.1 - 4.1e-55 186.3 1.2 5.1e-55 186.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) zf-CCCH PF00642.24 OAG02008.1 - 8.7e-09 35.1 17.7 2.9e-07 30.2 2.5 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OAG02008.1 - 2e-06 27.5 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAG02008.1 - 0.0057 16.7 3.3 0.0057 16.7 3.3 2.8 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 OAG02008.1 - 0.11 13.2 6.5 0.49 11.1 0.2 2.5 3 0 0 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 OAG02008.1 - 6.6 7.0 9.5 0.44 10.8 1.6 2.4 2 2 0 2 2 2 0 Zinc-finger containing family Tyrosinase PF00264.20 OAG02011.1 - 1.8e-53 182.1 0.1 2.5e-53 181.6 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase LysM PF01476.20 OAG02012.1 - 0.021 14.9 0.1 0.092 12.8 0.0 2.0 2 0 0 2 2 2 0 LysM domain UDPGP PF01704.18 OAG02014.1 - 1.2e-192 640.1 0.0 1.4e-192 639.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 OAG02014.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Pilus assembly protein, PilO FolB PF02152.18 OAG02015.1 - 2.2e-31 108.7 0.0 3.1e-21 76.0 0.1 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase TPR_2 PF07719.17 OAG02016.1 - 4.5e-15 54.5 12.5 6.8e-06 25.8 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG02016.1 - 1.8e-14 52.8 14.6 1.1e-05 25.1 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG02016.1 - 5.2e-13 48.4 5.0 2e-06 27.4 0.0 3.7 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.6 OAG02016.1 - 9.6e-07 29.3 2.0 0.0052 17.4 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG02016.1 - 1.4e-05 25.3 4.7 0.082 13.2 0.1 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG02016.1 - 3.9e-05 24.1 0.6 7.2 7.7 0.0 4.3 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG02016.1 - 4.1e-05 23.5 14.5 0.15 12.3 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG02016.1 - 7.2e-05 23.2 0.3 0.15 12.6 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG02016.1 - 0.0013 19.0 0.7 0.014 15.7 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG02016.1 - 0.0025 17.7 3.0 4.5 7.5 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 OAG02016.1 - 0.038 14.0 9.5 0.8 9.8 0.6 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 OAG02016.1 - 0.056 13.3 2.0 3.4 7.7 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 OAG02016.1 - 0.056 13.2 1.4 0.11 12.2 1.4 1.4 1 1 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2524 PF10732.9 OAG02016.1 - 0.087 13.1 3.6 9.9 6.5 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2524) ATP-synt_B PF00430.18 OAG02016.1 - 0.098 12.7 1.6 0.15 12.1 1.6 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) HMGL-like PF00682.19 OAG02016.1 - 0.17 11.4 0.2 0.22 11.0 0.2 1.2 1 0 0 1 1 1 0 HMGL-like ART PF01129.18 OAG02016.1 - 0.43 9.8 6.3 3.8 6.8 3.0 2.1 1 1 1 2 2 2 0 NAD:arginine ADP-ribosyltransferase TPR_3 PF07720.12 OAG02016.1 - 0.66 10.0 8.8 3.1 7.9 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG02016.1 - 1.3 9.9 7.5 54 4.7 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat MAP70 PF07058.11 OAG02017.1 - 0.0099 14.7 1.5 0.013 14.3 1.5 1.1 1 0 0 1 1 1 1 Microtubule-associated protein 70 bZIP_1 PF00170.21 OAG02017.1 - 0.022 14.9 9.3 0.022 14.9 9.3 1.6 2 0 0 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 OAG02017.1 - 0.068 12.0 4.2 0.09 11.6 4.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4094 PF13334.6 OAG02017.1 - 0.078 13.4 0.5 0.13 12.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) EMP24_GP25L PF01105.24 OAG02017.1 - 0.081 12.9 0.5 0.11 12.4 0.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 OAG02017.1 - 0.11 12.9 0.6 0.25 11.8 0.6 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ARA70 PF12489.8 OAG02017.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Nuclear coactivator DUF4407 PF14362.6 OAG02017.1 - 0.13 11.6 1.8 0.18 11.1 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 OAG02017.1 - 0.15 12.5 5.0 0.28 11.6 5.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RIC3 PF15361.6 OAG02017.1 - 0.28 11.6 1.1 0.49 10.8 1.1 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 TSNAXIP1_N PF15739.5 OAG02017.1 - 0.33 11.3 4.5 0.48 10.8 4.5 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DivIC PF04977.15 OAG02017.1 - 2.9 7.7 5.2 5 7.0 5.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Methyltransf_31 PF13847.6 OAG02018.1 - 1.6e-30 105.9 0.0 2.2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02018.1 - 3.6e-23 82.1 0.3 1.3e-22 80.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02018.1 - 1.8e-20 73.4 0.2 5.8e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG02018.1 - 1.3e-16 60.7 0.1 2.3e-16 59.9 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OAG02018.1 - 7e-13 48.6 0.2 1.1e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OAG02018.1 - 2.8e-12 46.8 0.0 4.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02018.1 - 6.8e-11 42.8 0.0 1.2e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG02018.1 - 3.8e-07 29.8 0.1 8e-07 28.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase small domain PCMT PF01135.19 OAG02018.1 - 4.4e-07 29.9 0.1 8.6e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OAG02018.1 - 7.2e-07 28.8 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OAG02018.1 - 4.3e-05 23.6 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAG02018.1 - 5.2e-05 23.0 0.1 0.00012 21.9 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 OAG02018.1 - 0.001 19.0 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG02018.1 - 0.0013 17.7 0.1 0.0065 15.4 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 OAG02018.1 - 0.0095 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 OAG02018.1 - 0.012 15.5 1.0 0.073 12.9 1.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 OAG02018.1 - 0.018 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 OAG02018.1 - 0.026 14.6 0.1 0.041 14.0 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 OAG02018.1 - 0.028 14.0 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltr_RsmB-F PF01189.17 OAG02018.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FliC_SP PF12613.8 OAG02018.1 - 4.8 7.8 7.6 0.5 10.9 1.7 2.2 2 0 0 2 2 2 0 Flagellin structural protein TPR_1 PF00515.28 OAG02019.1 - 4.1e-07 29.5 2.4 0.15 12.0 0.2 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG02019.1 - 5.2e-06 26.2 3.3 0.32 11.2 0.2 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG02019.1 - 3.3e-05 24.1 1.6 2.5 8.5 0.0 2.9 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG02019.1 - 0.00055 20.5 0.3 1.6 9.8 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG02019.1 - 0.0024 17.9 1.0 5.5 7.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG02019.1 - 0.0026 18.3 0.0 7 7.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG02019.1 - 0.0051 17.4 0.1 4.1 8.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG02019.1 - 0.0053 16.7 0.8 2.4 8.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG02019.1 - 0.059 13.3 0.4 22 5.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HET PF06985.11 OAG02020.1 - 1.4e-25 90.3 0.0 3.1e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Carb_anhydrase PF00194.21 OAG02021.1 - 1.6e-18 67.2 0.1 2.9e-18 66.3 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MFS_1 PF07690.16 OAG02023.1 - 1.6e-42 145.7 52.3 6e-42 143.8 50.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG02023.1 - 2.4e-08 32.9 22.6 3.6e-08 32.3 22.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG02024.1 - 3.2e-22 79.0 58.1 4.1e-12 45.7 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0444 PF15475.6 OAG02024.1 - 3.8 7.9 7.6 0.61 10.4 0.4 3.0 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 Trp_halogenase PF04820.14 OAG02026.1 - 7.7e-09 34.9 0.1 0.066 12.1 0.0 3.7 3 1 1 4 4 4 3 Tryptophan halogenase DAO PF01266.24 OAG02026.1 - 0.0029 17.2 0.1 0.029 13.9 0.1 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lig_chan-Glu_bd PF10613.9 OAG02026.1 - 0.13 12.4 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site Pyr_redox_2 PF07992.14 OAG02026.1 - 0.22 10.7 0.0 0.78 8.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_4 PF13637.6 OAG02027.1 - 4.5e-13 49.4 1.7 2.6e-06 27.9 0.1 4.5 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG02027.1 - 6.8e-13 49.0 0.0 5.8e-08 33.2 0.0 3.2 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG02027.1 - 3.2e-10 39.4 1.2 0.0068 16.8 0.1 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OAG02027.1 - 3e-08 33.8 2.9 0.00016 21.9 0.2 4.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG02027.1 - 2.6e-07 30.8 1.0 0.012 16.0 0.1 5.1 5 1 0 5 5 5 1 Ankyrin repeat Glyco_hydro_47 PF01532.20 OAG02028.1 - 1.6e-114 383.3 0.0 2.1e-114 382.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 NIF PF03031.18 OAG02029.1 - 2.6e-41 141.0 0.0 4.7e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aldo_ket_red PF00248.21 OAG02032.1 - 2.1e-40 138.7 0.0 9.3e-38 130.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family B12-binding PF02310.19 OAG02032.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 B12 binding domain Myb_DNA-bind_6 PF13921.6 OAG02034.1 - 0.05 13.9 0.5 8.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain ER_lumen_recept PF00810.18 OAG02036.1 - 8.3e-39 133.7 8.0 1.1e-38 133.3 8.0 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor Zn_clus PF00172.18 OAG02037.1 - 2.8e-07 30.6 11.6 4.4e-07 29.9 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 OAG02037.1 - 8.2 7.0 6.2 17 6.0 0.9 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Methyltransf_23 PF13489.6 OAG02038.1 - 1e-15 57.9 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02038.1 - 3.7e-14 53.2 1.0 7.7e-14 52.2 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02038.1 - 8.7e-14 52.0 1.3 1.4e-12 48.1 0.2 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02038.1 - 1.1e-13 51.6 0.1 1.3e-12 48.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG02038.1 - 2.7e-12 46.7 0.0 1.6e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG02038.1 - 7.6e-05 22.7 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OAG02038.1 - 0.0092 15.6 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 OAG02038.1 - 0.0099 15.4 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase TPMT PF05724.11 OAG02038.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 OAG02038.1 - 0.012 14.6 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 OAG02038.1 - 0.015 15.0 0.0 0.073 12.8 0.0 2.0 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 OAG02038.1 - 0.02 15.9 0.2 0.044 14.8 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAG02038.1 - 0.035 13.7 0.1 0.061 12.9 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase small domain ChaC PF04752.12 OAG02038.1 - 0.057 13.5 0.0 6.5 6.8 0.0 2.1 1 1 1 2 2 2 0 ChaC-like protein DUF938 PF06080.12 OAG02038.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 OAG02038.1 - 0.082 12.2 0.0 0.46 9.8 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAG02038.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 OAG02038.1 - 0.19 10.7 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Adaptin_binding PF10199.9 OAG02039.1 - 0.0056 17.3 1.4 0.061 13.9 1.4 2.2 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 LSM PF01423.22 OAG02040.1 - 2.8e-16 58.9 0.2 3.6e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG02040.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_S21e PF01249.18 OAG02040.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S21e PGP_phosphatase PF09419.10 OAG02041.1 - 2.1e-68 229.2 0.0 2.5e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 OAG02041.1 - 8.4e-06 25.8 0.0 1.3e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 HAD-hyrolase-like Orexin PF02072.15 OAG02043.1 - 0.0059 16.5 0.2 0.017 15.0 0.2 1.8 1 0 0 1 1 1 1 Prepro-orexin CDC14 PF08045.11 OAG02044.1 - 1.1e-115 385.7 0.0 1.2e-115 385.5 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component PAP2_3 PF14378.6 OAG02045.1 - 2.2e-32 112.3 28.5 2.3e-17 63.3 0.3 3.5 3 1 1 4 4 4 3 PAP2 superfamily PAP2 PF01569.21 OAG02045.1 - 0.0037 17.0 0.8 0.0037 17.0 0.8 2.2 2 1 1 3 3 3 1 PAP2 superfamily OCRE PF17780.1 OAG02046.1 - 0.058 13.4 0.7 0.14 12.2 0.7 1.7 1 0 0 1 1 1 0 OCRE domain CBM-like PF14683.6 OAG02047.1 - 9.8e-35 119.9 0.4 9.8e-35 119.9 0.4 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 OAG02047.1 - 1.4e-16 60.1 1.5 7.2e-16 57.7 1.5 2.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OAG02047.1 - 1.5e-07 31.6 0.8 7.9e-07 29.3 0.7 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain RhgB_N PF09284.10 OAG02047.1 - 0.001 18.7 0.0 0.0045 16.6 0.0 2.0 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal DUF4198 PF10670.9 OAG02047.1 - 0.0014 19.1 0.5 0.0046 17.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4198) CarbopepD_reg_2 PF13715.6 OAG02047.1 - 0.017 15.1 0.9 0.35 10.9 0.2 3.1 2 1 0 2 2 2 0 CarboxypepD_reg-like domain WSC PF01822.19 OAG02048.1 - 4.1e-23 81.4 30.3 1.6e-11 44.2 7.3 2.4 2 0 0 2 2 2 2 WSC domain CFEM PF05730.11 OAG02049.1 - 1.8e-13 50.3 11.6 1.8e-13 50.3 11.6 1.5 2 0 0 2 2 2 1 CFEM domain Fungal_trans PF04082.18 OAG02051.1 - 5e-20 71.7 0.1 7.6e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02051.1 - 7.9e-16 57.9 26.0 2.5e-08 33.9 9.1 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2520 PF10728.9 OAG02051.1 - 0.091 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) AnkUBD PF18418.1 OAG02052.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Ankyrin ubiquitin-binding domain ELP6 PF09807.9 OAG02052.1 - 0.17 11.3 0.0 0.19 11.1 0.0 1.0 1 0 0 1 1 1 0 Elongation complex protein 6 Mannosyl_trans3 PF11051.8 OAG02053.1 - 0.0087 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 OAG02053.1 - 0.015 14.9 3.4 0.28 10.7 0.1 2.1 1 1 0 2 2 2 0 Glycosyl transferase family 8 APH PF01636.23 OAG02054.1 - 2.7e-41 142.1 0.0 4.9e-41 141.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG02054.1 - 0.00076 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OAG02054.1 - 0.0013 18.3 0.0 0.004 16.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.20 OAG02054.1 - 0.0077 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 OAG02054.1 - 0.0079 15.4 0.0 0.15 11.2 0.0 2.2 2 1 0 2 2 2 1 Fructosamine kinase DUF1679 PF07914.11 OAG02054.1 - 0.0095 14.8 0.0 0.24 10.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Kdo PF06293.14 OAG02054.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl-CoA_dh_1 PF00441.24 OAG02055.1 - 2e-23 83.3 0.3 3e-23 82.7 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG02055.1 - 1.6e-13 51.3 0.0 3.6e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG02055.1 - 2.4e-07 31.1 0.0 4.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG02055.1 - 4.2e-06 26.9 0.0 1.2e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain RNA_pol_Rbc25 PF08292.12 OAG02055.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Abhydrolase_3 PF07859.13 OAG02056.1 - 1.9e-46 158.6 0.0 2.6e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG02056.1 - 4.2e-09 35.8 0.9 1.9e-08 33.7 0.9 1.8 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 OAG02056.1 - 0.14 11.8 2.1 2.6 7.6 2.1 2.6 1 1 0 1 1 1 0 Putative esterase CorA PF01544.18 OAG02057.1 - 5.5e-10 39.0 0.0 9.1e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ADH_zinc_N PF00107.26 OAG02058.1 - 1.1e-23 83.6 0.3 1.8e-23 82.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG02058.1 - 2e-18 66.3 0.5 4e-18 65.3 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG02058.1 - 8.3e-06 25.2 0.1 1.4e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OAG02058.1 - 0.00011 22.4 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 OAG02058.1 - 0.00018 20.9 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAG02058.1 - 0.0011 19.6 0.1 0.0027 18.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02058.1 - 0.0031 18.1 0.2 0.0077 16.9 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG02058.1 - 0.014 14.7 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 3HCDH_N PF02737.18 OAG02058.1 - 0.014 15.3 0.3 0.025 14.5 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglD_N PF17836.1 OAG02058.1 - 0.019 15.6 0.9 0.044 14.4 0.2 2.0 2 0 0 2 2 2 0 PglD N-terminal domain UCR_14kD PF02271.16 OAG02058.1 - 0.022 14.7 0.2 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit ELFV_dehydrog PF00208.21 OAG02058.1 - 0.03 14.0 0.2 0.051 13.3 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_31 PF13847.6 OAG02058.1 - 0.077 12.8 0.1 0.31 10.8 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain EthD PF07110.11 OAG02059.1 - 4.2e-16 59.9 1.6 5.3e-16 59.6 1.6 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG02059.1 - 0.00092 19.6 0.4 0.0014 19.0 0.4 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase TRI12 PF06609.13 OAG02060.1 - 1.6e-31 109.4 16.9 2e-31 109.1 16.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG02060.1 - 8.9e-24 84.1 42.2 8.9e-24 84.1 42.2 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG02060.1 - 2.5e-05 23.3 12.8 2.5e-05 23.3 12.8 3.9 2 2 0 3 3 3 1 Sugar (and other) transporter DUF373 PF04123.13 OAG02060.1 - 0.57 9.6 2.4 1.3 8.4 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Fungal_trans PF04082.18 OAG02062.1 - 1.1e-16 60.7 0.0 2.5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02062.1 - 7.9e-06 25.9 10.1 1.4e-05 25.1 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 OAG02062.1 - 8.5 5.0 5.6 15 4.2 5.6 1.4 1 0 0 1 1 1 0 Presenilin FMO-like PF00743.19 OAG02063.1 - 2.3e-13 49.4 0.2 7e-13 47.8 0.1 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG02063.1 - 5.7e-10 39.3 0.0 1.6e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG02063.1 - 0.00011 22.2 0.0 0.001 19.0 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG02063.1 - 0.00017 20.9 0.0 0.0032 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG02063.1 - 0.0048 16.2 0.0 1.6 7.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG02063.1 - 0.014 15.0 0.0 0.15 11.6 0.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase AMP-binding PF00501.28 OAG02064.1 - 2.1e-86 290.2 0.0 2.7e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG02064.1 - 2.2e-11 44.6 0.1 5.6e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 OAG02065.1 - 1.2e-49 169.0 0.0 1.5e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG02065.1 - 1.4e-40 138.9 0.0 1.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG02065.1 - 8.9e-12 45.3 0.1 1.2e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG02065.1 - 0.038 13.5 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG02065.1 - 0.072 12.5 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAG02066.1 - 9.2e-32 110.1 0.0 1.3e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02066.1 - 1.6e-23 83.5 0.0 2.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG02066.1 - 0.0041 17.0 0.1 0.046 13.6 0.0 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG02066.1 - 0.083 12.3 0.2 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_9 PF13454.6 OAG02066.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Aldedh PF00171.22 OAG02067.1 - 2.6e-161 537.2 0.0 3e-161 537.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG02067.1 - 0.082 12.4 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) PGC7_Stella PF15549.6 OAG02069.1 - 1.9 8.4 7.0 4.6 7.2 0.0 3.1 2 1 1 3 3 3 0 PGC7/Stella/Dppa3 domain Methyltransf_19 PF04672.12 OAG02070.1 - 1.6e-15 57.4 0.0 1.9e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_3 PF01596.17 OAG02070.1 - 0.063 12.4 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Gly_transf_sug PF04488.15 OAG02071.1 - 1.1e-07 32.3 0.1 4.3e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAG02071.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Methyltransf_31 PF13847.6 OAG02072.1 - 2.7e-12 46.8 0.0 5.6e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02072.1 - 3.3e-12 46.9 0.0 1.1e-11 45.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02072.1 - 1.8e-10 41.3 0.0 6.7e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02072.1 - 1.1e-07 32.5 0.0 3.6e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG02072.1 - 5.5e-07 29.6 0.1 3e-06 27.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG02072.1 - 8.5e-05 22.0 0.0 0.00036 19.9 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG02072.1 - 0.00091 18.8 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG02072.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain OTCace PF00185.24 OAG02072.1 - 0.062 13.4 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain RNA_pol_Rpc34 PF05158.12 OAG02073.1 - 9.5e-65 219.2 0.0 1.4e-63 215.3 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.6 OAG02073.1 - 0.0071 15.9 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 OAG02073.1 - 0.032 14.1 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 HxlR-like helix-turn-helix MarR PF01047.22 OAG02073.1 - 0.034 14.1 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 OAG02073.1 - 0.042 13.7 0.0 0.47 10.4 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_45 PF14947.6 OAG02073.1 - 0.2 11.7 0.3 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix TRI12 PF06609.13 OAG02074.1 - 2.4e-81 274.0 21.0 3e-81 273.6 21.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG02074.1 - 6.4e-18 64.8 54.3 1.7e-17 63.4 50.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG02074.1 - 3.3e-07 29.5 7.9 3.3e-07 29.5 7.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TMEM100 PF16311.5 OAG02074.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.6 3 0 0 3 3 3 0 Transmembrane protein 100 Rick_17kDa_Anti PF05433.15 OAG02076.1 - 0.00019 21.2 13.8 0.0047 16.8 14.5 2.1 1 1 1 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OAG02076.1 - 4.6 7.3 11.8 10 6.2 3.0 2.1 1 1 1 2 2 2 0 Glycine zipper PT-VENN PF04829.13 OAG02076.1 - 7.2 6.8 5.1 15 5.7 5.1 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif cNMPbd_u2 PF16643.5 OAG02077.1 - 3.8e-40 137.9 15.4 3.8e-40 137.9 15.4 2.1 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 OAG02077.1 - 1.3e-33 114.9 0.0 1.2e-19 70.1 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 OAG02077.1 - 5.7e-10 38.4 2.5 1 9.6 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 OAG02077.1 - 1.6e-06 28.3 3.8 0.84 10.2 0.0 6.1 4 1 6 10 10 10 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAG02077.1 - 3e-06 27.0 0.6 2.7e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG02077.1 - 3.6e-05 23.5 6.4 4.1e-05 23.3 0.4 3.2 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 OAG02077.1 - 0.0053 17.1 7.2 67 4.6 0.0 7.2 7 1 0 7 7 7 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 OAG02077.1 - 0.049 13.9 0.1 7.7 6.8 0.1 3.4 3 0 0 3 3 3 0 Ste50p, sterile alpha motif LRR_8 PF13855.6 OAG02077.1 - 0.077 12.8 0.1 15 5.5 0.0 3.3 2 1 1 3 3 3 0 Leucine rich repeat NAD_binding_8 PF13450.6 OAG02078.1 - 4.1e-12 46.1 0.0 1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG02078.1 - 7.3e-10 37.9 0.1 4.1e-08 32.1 0.1 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG02078.1 - 7.5e-07 28.7 0.0 6.3e-06 25.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG02078.1 - 1.1e-06 28.1 0.0 0.0047 16.2 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG02078.1 - 1.5e-06 28.0 0.0 0.014 15.0 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG02078.1 - 0.0017 17.5 0.1 3.3 6.8 0.0 3.5 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG02078.1 - 0.002 18.1 0.0 0.01 15.8 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG02078.1 - 0.092 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OAG02078.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family adh_short_C2 PF13561.6 OAG02079.1 - 7.9e-55 186.0 0.9 9.9e-55 185.6 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG02079.1 - 6.1e-44 149.8 0.4 8.2e-44 149.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG02079.1 - 5.3e-11 42.7 0.1 8.2e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG02079.1 - 0.012 15.1 0.4 0.037 13.5 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Adenylsucc_synt PF00709.21 OAG02079.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenylosuccinate synthetase eRF1_1 PF03463.15 OAG02080.1 - 3e-45 153.4 0.0 5.7e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 OAG02080.1 - 2.2e-16 60.3 0.0 4e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 OAG02080.1 - 1.3e-11 44.9 0.0 2.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 F-box-like PF12937.7 OAG02083.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 F-box-like zf-NADH-PPase PF09297.11 OAG02085.1 - 0.00061 19.4 0.5 0.00096 18.8 0.5 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_4 PF13717.6 OAG02085.1 - 0.0043 16.9 0.3 2.1 8.3 0.0 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAG02085.1 - 0.0056 16.8 1.4 2.6 8.2 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain zf-ribbon_3 PF13248.6 OAG02085.1 - 0.012 15.0 1.8 0.1 12.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.21 OAG02085.1 - 0.018 15.3 0.5 0.023 14.9 0.5 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf_UBZ PF18439.1 OAG02085.1 - 0.065 12.8 1.1 7 6.3 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_5 PF13719.6 OAG02085.1 - 0.11 12.3 2.0 1.2 8.9 2.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-ACC PF17848.1 OAG02085.1 - 0.39 10.8 4.7 1.1 9.3 0.5 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Beach PF02138.18 OAG02086.1 - 1.8e-109 365.4 0.1 3.3e-109 364.6 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OAG02086.1 - 4.1e-11 42.9 3.1 1.3e-09 38.1 0.0 2.6 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OAG02086.1 - 3.7e-08 33.6 0.0 8.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 OAG02086.1 - 0.00036 19.9 0.0 0.00095 18.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) WD40 PF00400.32 OAG02086.1 - 0.00056 20.7 1.8 1.1 10.3 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat V-ATPase_H_N PF03224.14 OAG02086.1 - 0.041 13.2 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 V-ATPase subunit H Exonuc_VII_L PF02601.15 OAG02086.1 - 9.3 5.7 7.4 1.3 8.5 3.0 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Peptidase_S8 PF00082.22 OAG02087.1 - 8e-37 127.1 9.8 1.2e-36 126.5 9.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG02087.1 - 1.7e-20 73.4 2.3 2.2e-20 73.1 0.8 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 BTB PF00651.31 OAG02088.1 - 1.7e-08 34.7 0.0 3.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.18 OAG02088.1 - 2.8e-07 30.5 8.2 9.4e-07 28.9 8.2 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG02088.1 - 0.00058 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SKG6 PF08693.10 OAG02089.1 - 0.014 14.8 0.3 0.029 13.8 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LCD1 PF09798.9 OAG02090.1 - 1.2 7.6 4.5 0.88 8.0 1.2 2.0 2 0 0 2 2 2 0 DNA damage checkpoint protein Dicty_REP PF05086.12 OAG02090.1 - 1.6 6.6 4.8 1.8 6.4 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sec62 PF03839.16 OAG02090.1 - 9.6 5.6 7.1 0.9 9.0 0.7 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 PAF-AH_p_II PF03403.13 OAG02091.1 - 4.1e-13 48.6 0.0 4.6e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 OAG02091.1 - 0.0043 17.7 0.2 0.0089 16.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OAG02091.1 - 0.007 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2974 PF11187.8 OAG02091.1 - 0.016 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 OAG02091.1 - 0.025 13.8 0.2 0.61 9.3 0.0 2.6 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 OAG02091.1 - 0.075 12.7 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Putative esterase AIG2_2 PF13772.6 OAG02092.1 - 1e-06 29.0 0.0 0.0016 18.8 0.0 2.2 2 0 0 2 2 2 2 AIG2-like family GGACT PF06094.12 OAG02092.1 - 2.5e-06 28.1 0.0 4.7e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like HTH_23 PF13384.6 OAG02092.1 - 0.057 13.2 0.1 0.057 13.2 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain MFS_1 PF07690.16 OAG02093.1 - 3.7e-26 91.9 31.0 1.1e-25 90.3 28.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Nitroreductase PF00881.24 OAG02094.1 - 3.3e-14 53.3 0.0 4e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family DUF1772 PF08592.11 OAG02095.1 - 1.3e-23 83.8 4.1 1.7e-23 83.5 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pkinase PF00069.25 OAG02097.1 - 1.7e-06 27.6 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OAG02097.1 - 2e-05 24.0 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 OAG02097.1 - 0.003 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 OAG02097.1 - 0.0087 16.0 0.5 0.085 12.8 0.5 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CheX PF13690.6 OAG02097.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX LRR_6 PF13516.6 OAG02098.1 - 0.12 12.5 0.0 0.44 10.7 0.0 2.1 1 0 0 1 1 1 0 Leucine Rich repeat p450 PF00067.22 OAG02099.1 - 3.5e-59 200.8 0.0 4.1e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bax1-I PF01027.20 OAG02100.1 - 8.7e-35 120.4 5.8 1.3e-34 119.9 5.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Epimerase PF01370.21 OAG02101.1 - 1.8e-09 37.4 0.0 3.9e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG02101.1 - 4.3e-06 25.9 0.0 6.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG02101.1 - 9.2e-06 25.7 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG02101.1 - 6.9e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OAG02101.1 - 0.0028 16.9 0.0 0.021 14.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG02101.1 - 0.0098 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TENA_THI-4 PF03070.16 OAG02104.1 - 2.3e-08 34.1 0.0 3.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family zf-BED PF02892.15 OAG02104.1 - 0.013 15.5 1.2 0.033 14.2 0.6 2.0 2 0 0 2 2 2 0 BED zinc finger Cellulase PF00150.18 OAG02105.1 - 3.7e-13 49.5 6.3 3e-12 46.6 6.3 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 OAG02105.1 - 0.0023 17.3 0.1 0.009 15.4 0.1 1.9 1 1 1 2 2 2 1 Beta-galactosidase GPI-anchored PF10342.9 OAG02107.1 - 1.8e-22 79.9 0.2 1.8e-22 79.9 0.2 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DJ-1_PfpI PF01965.24 OAG02108.1 - 3.4e-14 53.0 0.0 4.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family p450 PF00067.22 OAG02109.1 - 1.3e-65 222.0 0.0 1.7e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Enoyl_reductase PF12241.8 OAG02109.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Cmc1 PF08583.10 OAG02109.1 - 0.22 11.6 1.0 10 6.2 0.2 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like ADH_zinc_N PF00107.26 OAG02110.1 - 3.6e-06 27.0 0.1 1.4e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG02110.1 - 0.0012 18.7 0.9 0.0031 17.4 0.1 2.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG02110.1 - 0.003 18.6 0.0 0.011 16.8 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase PTSIIA_gutA PF03829.13 OAG02110.1 - 0.045 13.6 0.1 0.38 10.6 0.1 2.1 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component BKACE PF05853.12 OAG02110.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Kinesin PF00225.23 OAG02111.1 - 1.2e-117 392.6 0.1 1.7e-117 392.1 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG02111.1 - 1.4e-27 96.5 0.0 3.5e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 OAG02111.1 - 0.061 13.5 0.0 0.41 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Tim17 PF02466.19 OAG02114.1 - 3.3e-07 30.7 0.0 1e-06 29.1 0.0 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_2_4 PF16082.5 OAG02114.1 - 0.09 12.5 0.2 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like LicD PF04991.13 OAG02115.1 - 1.8e-22 80.6 5.3 1.9e-15 57.6 2.2 2.1 1 1 1 2 2 2 2 LicD family DUF3405 PF11885.8 OAG02116.1 - 1.2e-204 680.7 13.5 4.3e-204 678.9 13.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) tRNA-synt_2d PF01409.20 OAG02117.1 - 7.1e-84 281.1 0.0 9.2e-84 280.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OAG02117.1 - 4.4e-17 62.1 3.2 1.5e-16 60.4 2.3 2.3 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 OAG02117.1 - 6.2e-07 28.8 0.2 0.00083 18.5 0.0 3.4 4 0 0 4 4 4 2 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 OAG02117.1 - 6.1e-05 22.9 2.7 0.00022 21.2 2.7 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 OAG02117.1 - 7.8e-05 22.2 0.0 0.015 14.7 0.0 2.5 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain NmrA PF05368.13 OAG02118.1 - 1.5e-50 172.0 0.0 1.8e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG02118.1 - 5.4e-11 42.7 0.1 8.3e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Abhydrolase_6 PF12697.7 OAG02122.1 - 5e-09 37.1 1.5 2.5e-08 34.8 1.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Amidase PF01425.21 OAG02123.1 - 1e-97 328.0 0.0 1.3e-97 327.7 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF4360 PF14273.6 OAG02124.1 - 6.5e-70 234.6 5.4 7.4e-70 234.4 5.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PMSR PF01625.21 OAG02125.1 - 3e-62 209.3 0.4 3.6e-62 209.1 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase GFA PF04828.14 OAG02126.1 - 1.9e-22 79.4 0.3 1.9e-22 79.4 0.3 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 OAG02127.1 - 8.7e-11 41.3 43.1 9.5e-09 34.6 22.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 OAG02128.1 - 0.014 15.5 13.8 0.042 13.9 13.8 1.8 1 1 0 1 1 1 0 Membrane-associating domain Glyco_hydr_30_2 PF14587.6 OAG02129.1 - 1.1e-16 61.4 0.1 2.7e-16 60.1 0.1 1.7 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 OAG02129.1 - 7.5e-13 48.4 0.1 1.1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 OAG02129.1 - 1.2e-10 41.4 7.5 1.2e-10 41.4 7.5 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 OAG02129.1 - 1.6e-07 30.6 0.1 2e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Melibiase_C PF17801.1 OAG02129.1 - 0.6 10.2 3.8 1.5 8.9 1.5 2.8 2 1 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain DUF1996 PF09362.10 OAG02130.1 - 2.7e-80 269.7 0.2 3.4e-80 269.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CENP-B_dimeris PF09026.10 OAG02131.1 - 3.9 7.9 11.6 9.9 6.6 11.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OAG02131.1 - 4.6 7.7 11.7 16 6.0 11.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.11 OAG02131.1 - 9.3 4.7 7.3 13 4.2 7.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Fungal_trans_2 PF11951.8 OAG02132.1 - 7.3e-15 54.7 0.4 1e-14 54.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02132.1 - 0.00035 20.6 9.0 0.00055 20.0 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 OAG02133.1 - 1.8e-39 135.5 1.0 2.7e-39 134.9 1.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF308 PF03729.13 OAG02133.1 - 1.9 8.9 8.4 0.3 11.4 0.6 3.0 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) ADP_ribosyl_GH PF03747.14 OAG02134.1 - 3.2e-47 161.6 0.5 4.8e-47 161.1 0.5 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase AMP-binding PF00501.28 OAG02135.1 - 1.4e-58 198.5 0.0 2.7e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 OAG02135.1 - 1e-16 61.0 6.6 0.00029 21.5 0.0 8.2 8 0 0 8 8 8 3 WD domain, G-beta repeat AMP-binding_C PF13193.6 OAG02135.1 - 1.4e-14 54.8 0.3 3.9e-14 53.4 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ANAPC4_WD40 PF12894.7 OAG02135.1 - 6.7e-05 23.1 0.0 0.12 12.7 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG02135.1 - 0.002 17.1 0.0 2 7.3 0.0 2.6 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein 2OG-FeII_Oxy_2 PF13532.6 OAG02136.1 - 3.7e-11 43.6 0.0 8.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.17 OAG02136.1 - 2.5e-08 33.8 0.3 4.6e-08 32.9 0.3 1.4 1 0 0 1 1 1 1 SAD/SRA domain TrkA_C PF02080.21 OAG02136.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-C domain ADH_zinc_N PF00107.26 OAG02137.1 - 1e-06 28.8 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG02137.1 - 0.0012 19.9 0.0 0.0019 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG02137.1 - 0.0013 18.6 0.1 0.003 17.4 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ocnus PF05005.15 OAG02137.1 - 0.0064 16.6 0.3 0.033 14.3 0.1 2.0 2 0 0 2 2 2 1 Janus/Ocnus family (Ocnus) Glyco_hydro_61 PF03443.14 OAG02138.1 - 8.3e-57 192.4 1.0 1e-56 192.2 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MtN3_slv PF03083.16 OAG02140.1 - 0.073 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DUF5044 PF16447.5 OAG02140.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5044) Rick_17kDa_Anti PF05433.15 OAG02141.1 - 7.6e-06 25.7 23.1 0.0003 20.6 14.5 2.1 1 1 2 3 3 3 3 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 OAG02141.1 - 0.069 12.9 13.3 0.15 11.8 13.3 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 OAG02141.1 - 3 7.9 18.1 25 5.0 17.9 2.4 1 1 1 2 2 2 0 Glycine zipper Syndecan PF01034.20 OAG02142.1 - 0.31 11.0 0.4 0.57 10.1 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Peptidase_M36 PF02128.15 OAG02143.1 - 3.6e-162 539.7 1.1 4.7e-162 539.4 1.1 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 OAG02143.1 - 1.5e-16 59.9 3.2 5.5e-16 58.1 3.2 2.1 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 OAG02143.1 - 0.02 14.7 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain TauD PF02668.16 OAG02144.1 - 8.3e-37 127.4 0.0 1e-36 127.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Transp_cyt_pur PF02133.15 OAG02145.1 - 8.3e-18 64.4 45.9 1.7e-17 63.4 45.9 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5453 PF17534.2 OAG02145.1 - 0.0017 18.4 2.5 0.0017 18.4 2.5 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5453) ZapB PF06005.12 OAG02146.1 - 0.0039 17.6 4.2 0.0039 17.6 4.2 4.5 4 0 0 4 4 4 1 Cell division protein ZapB CorA PF01544.18 OAG02146.1 - 0.27 10.5 13.4 0.093 12.0 7.0 2.6 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Fez1 PF06818.15 OAG02146.1 - 0.29 11.6 41.7 0.53 10.7 20.3 3.6 2 1 1 3 3 3 0 Fez1 NFACT-R_1 PF05670.13 OAG02146.1 - 0.53 11.0 3.6 24 5.6 0.1 3.2 3 0 0 3 3 3 0 NFACT protein RNA binding domain DUF641 PF04859.12 OAG02146.1 - 0.55 10.6 26.5 1.8 8.9 7.1 3.7 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Zn_clus PF00172.18 OAG02146.1 - 0.98 9.6 11.0 2.7 8.2 11.0 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Laminin_II PF06009.12 OAG02146.1 - 1.7 8.6 19.1 2.7 8.0 6.6 3.7 2 1 2 4 4 4 0 Laminin Domain II GAS PF13851.6 OAG02146.1 - 2.5 7.4 46.3 0.045 13.1 6.7 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 OAG02146.1 - 4.6 7.6 14.1 4.5 7.7 0.7 4.3 4 0 0 4 4 4 0 TSC-22/dip/bun family Rab_bind PF16704.5 OAG02146.1 - 4.7 7.3 9.4 0.58 10.2 2.6 2.9 2 1 1 3 3 3 0 Rab binding domain MAD PF05557.13 OAG02146.1 - 5.2 5.3 40.0 0.66 8.3 18.4 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF1478 PF07349.11 OAG02147.1 - 0.016 15.2 0.7 0.023 14.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) TNFR_16_TM PF18422.1 OAG02147.1 - 0.51 10.3 2.7 6.8 6.7 1.3 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain HSP70 PF00012.20 OAG02148.1 - 4.3e-97 325.7 0.6 1e-58 199.0 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein FlgH PF02107.16 OAG02148.1 - 0.018 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar L-ring protein MreB_Mbl PF06723.13 OAG02148.1 - 0.043 12.6 0.0 0.087 11.6 0.0 1.5 1 0 0 1 1 1 0 MreB/Mbl protein hnRNP_Q_AcD PF18360.1 OAG02148.1 - 0.14 12.1 0.0 0.46 10.5 0.0 1.9 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain SLS PF14611.6 OAG02148.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator SLAC1 PF03595.17 OAG02149.1 - 3.4e-71 240.2 32.6 4e-71 239.9 32.6 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel RseC_MucC PF04246.12 OAG02149.1 - 0.51 10.3 2.5 3.8 7.5 0.7 2.7 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TRP PF06011.12 OAG02150.1 - 2.5e-40 138.5 22.5 1.9e-38 132.3 22.5 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG02150.1 - 1.7e-21 77.0 0.0 2.6e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF2254 PF10011.9 OAG02150.1 - 0.41 9.4 3.6 4.2 6.1 0.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) FYVE PF01363.21 OAG02151.1 - 2.8e-21 75.4 1.4 2.8e-21 75.4 1.4 2.7 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 OAG02151.1 - 4.6e-07 30.1 4.2 4.6e-07 30.1 4.2 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG02151.1 - 2.9e-05 23.8 2.8 2.9e-05 23.8 2.8 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 OAG02151.1 - 0.0063 16.7 2.8 0.0063 16.7 2.8 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4 PF00097.25 OAG02151.1 - 0.0069 16.2 2.1 0.0069 16.2 2.1 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG02151.1 - 0.0077 16.0 5.9 0.0077 16.0 5.9 2.4 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 OAG02151.1 - 0.024 14.8 3.5 0.024 14.8 3.5 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 OAG02151.1 - 0.11 12.4 1.3 0.2 11.5 0.2 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Fungal_trans PF04082.18 OAG02152.1 - 5.8e-13 48.5 0.3 2.4e-12 46.5 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain RNB PF00773.19 OAG02153.1 - 2.7e-53 181.4 0.0 1e-52 179.5 0.0 1.8 1 1 0 1 1 1 1 RNB domain NAD_binding_9 PF13454.6 OAG02153.1 - 0.17 11.9 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiS PF02597.20 OAG02154.1 - 1.4e-08 35.2 0.0 3.5e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 ThiS family Zn_clus PF00172.18 OAG02155.1 - 1e-06 28.7 14.2 1.7e-06 28.1 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG02155.1 - 0.0002 20.5 5.5 0.00038 19.6 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain MerR-DNA-bind PF09278.11 OAG02155.1 - 0.092 13.3 0.2 0.31 11.6 0.2 1.9 1 0 0 1 1 1 0 MerR, DNA binding Velvet PF11754.8 OAG02155.1 - 0.16 11.9 8.6 0.39 10.6 8.6 1.5 1 0 0 1 1 1 0 Velvet factor DOCK_N PF16172.5 OAG02155.1 - 0.28 10.0 7.9 12 4.7 0.0 2.7 2 1 0 2 2 2 0 DOCK N-terminus Apt1 PF10351.9 OAG02155.1 - 1.3 7.8 8.7 2.3 7.0 8.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 OAG02155.1 - 1.5 6.9 9.4 2.3 6.3 9.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5427 PF10310.9 OAG02155.1 - 6.9 5.5 14.2 12 4.7 14.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Suf PF05843.14 OAG02155.1 - 7.1 6.5 16.0 0.72 9.8 9.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) adh_short_C2 PF13561.6 OAG02156.1 - 1e-53 182.3 0.1 1.2e-53 182.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG02156.1 - 8.5e-41 139.6 0.5 1e-40 139.3 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG02156.1 - 4.3e-07 30.0 0.3 6.6e-07 29.4 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG02156.1 - 0.029 13.8 0.1 0.081 12.4 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG02156.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Tri3 PF07428.11 OAG02157.1 - 0.0017 17.3 0.0 0.0033 16.4 0.0 1.4 2 0 0 2 2 2 1 15-O-acetyltransferase Tri3 Condensation PF00668.20 OAG02157.1 - 0.053 12.2 0.2 0.3 9.7 0.1 1.9 2 0 0 2 2 2 0 Condensation domain FAD_binding_3 PF01494.19 OAG02158.1 - 1.9e-15 56.9 1.7 2.3e-08 33.7 0.1 3.3 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 OAG02158.1 - 1e-08 35.1 0.9 0.0002 21.1 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG02158.1 - 1.4e-08 34.4 0.0 0.00023 20.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG02158.1 - 2.1e-08 33.7 0.0 8.4e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG02158.1 - 1e-07 31.0 0.1 0.00025 19.9 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 OAG02158.1 - 3.4e-07 29.8 0.0 0.00061 19.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG02158.1 - 9.7e-07 28.9 0.3 3.1e-06 27.3 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG02158.1 - 8.6e-06 25.1 0.1 0.0008 18.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG02158.1 - 1.8e-05 24.3 0.0 3.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG02158.1 - 0.00084 19.9 0.3 0.022 15.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG02158.1 - 0.00098 18.3 1.0 0.043 12.9 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 OAG02158.1 - 0.0027 17.0 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 OAG02158.1 - 0.0044 16.4 0.0 2 7.6 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG02158.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OAG02158.1 - 0.069 13.1 0.2 14 5.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAG02158.1 - 0.12 11.2 0.2 1 8.2 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_16 PF00722.21 OAG02160.1 - 2.3e-43 147.7 2.2 4.4e-43 146.8 2.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MSP1_C PF07462.11 OAG02160.1 - 6.3 5.4 7.1 13 4.4 7.1 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SR-25 PF10500.9 OAG02160.1 - 7.2 6.1 13.6 14 5.2 13.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cu-oxidase_3 PF07732.15 OAG02161.1 - 3.1e-38 130.5 1.6 1.8e-37 128.0 0.9 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG02161.1 - 2.3e-34 118.1 2.7 3.7e-33 114.1 0.1 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG02161.1 - 3e-25 89.2 0.1 5.6e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase SET PF00856.28 OAG02162.1 - 1.2e-13 51.7 0.0 4.8e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-FLZ PF04570.14 OAG02162.1 - 0.28 10.7 3.1 0.76 9.3 3.1 1.7 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Fungal_trans_2 PF11951.8 OAG02163.1 - 4.2e-12 45.6 0.1 2.4e-09 36.5 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02163.1 - 2.6e-07 30.6 8.4 4.1e-07 30.0 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_luciferase PF00296.20 OAG02164.1 - 1.6e-59 201.9 1.2 2.3e-59 201.3 1.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_28 PF00295.17 OAG02165.1 - 3e-51 174.4 15.9 4.8e-51 173.7 15.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Forkhead PF00250.18 OAG02166.1 - 2.9e-23 81.9 0.0 6.4e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain PHC2_SAM_assoc PF16616.5 OAG02166.1 - 0.083 13.7 5.7 0.23 12.3 5.7 1.8 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 CactinC_cactus PF09732.9 OAG02167.1 - 7e-58 194.0 6.6 1.1e-57 193.4 6.6 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 OAG02167.1 - 9.3e-52 175.6 6.9 9.3e-52 175.6 6.9 2.5 1 1 1 2 2 2 1 Conserved mid region of cactin SF3A2 PF16835.5 OAG02167.1 - 0.029 14.7 0.0 0.16 12.4 0.0 2.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) XLF PF09302.11 OAG02168.1 - 3.5e-43 147.8 2.9 3.5e-43 147.8 2.9 1.7 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component C2 PF00168.30 OAG02169.1 - 4.2e-81 267.9 0.0 4.1e-22 78.4 0.0 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 OAG02169.1 - 9.1e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain F-box PF00646.33 OAG02171.1 - 0.004 17.0 0.1 0.009 15.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain DUF4756 PF15948.5 OAG02171.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) F-box-like PF12937.7 OAG02171.1 - 0.017 15.0 0.4 0.045 13.6 0.4 1.7 1 0 0 1 1 1 0 F-box-like LpxI_N PF17930.1 OAG02171.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain Peptidase_C14 PF00656.22 OAG02172.1 - 6.4e-42 144.2 0.0 8e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain GFA PF04828.14 OAG02173.1 - 1.1e-19 70.6 1.2 1.8e-19 69.9 1.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FAD_binding_2 PF00890.24 OAG02174.1 - 1.6e-36 126.3 0.0 2.1e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG02174.1 - 3.6e-05 23.5 0.3 0.00078 19.1 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG02174.1 - 0.0025 17.1 0.0 0.028 13.7 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG02174.1 - 0.035 12.8 0.2 3.8 6.1 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 OAG02174.1 - 0.15 12.6 0.5 1 9.9 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S21e PF01249.18 OAG02175.1 - 8.6e-42 141.1 0.0 9.6e-42 141.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e WD40 PF00400.32 OAG02176.1 - 3.8e-13 49.7 8.6 3.5e-06 27.6 0.7 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 OAG02176.1 - 3.8e-08 33.4 0.2 0.0081 16.1 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OAG02176.1 - 1.4e-06 28.5 0.2 0.097 13.0 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 PF17120.5 OAG02176.1 - 0.0012 18.4 11.7 0.0029 17.2 11.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 OAG02176.1 - 0.79 10.1 10.9 0.18 12.1 1.0 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain ABC_membrane PF00664.23 OAG02177.1 - 3.3e-36 125.4 4.4 3.3e-36 125.4 4.4 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG02177.1 - 3.7e-32 111.7 0.0 8.7e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG02177.1 - 1.7e-06 27.6 0.1 5.6e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OAG02177.1 - 0.08 13.2 3.6 0.2 11.9 0.3 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 OAG02177.1 - 0.15 11.8 0.0 0.26 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OAG02177.1 - 0.16 11.8 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AA_permease_2 PF13520.6 OAG02177.1 - 0.34 9.7 12.1 0.028 13.3 5.9 2.2 2 1 0 2 2 2 0 Amino acid permease Peptidase_U4 PF03419.13 OAG02177.1 - 3.6 6.8 11.3 2.3 7.4 0.0 3.6 4 0 0 4 4 4 0 Sporulation factor SpoIIGA Methyltransf_23 PF13489.6 OAG02178.1 - 6.3e-17 61.9 0.0 9.3e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02178.1 - 4.3e-11 43.4 0.0 8.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02178.1 - 1.3e-09 38.6 0.0 4.1e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02178.1 - 1.3e-08 35.4 0.0 2.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG02178.1 - 1.1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG02178.1 - 0.007 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 OAG02178.1 - 0.0076 15.6 0.0 0.022 14.1 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG02178.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OAG02178.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 OAG02178.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 OAG02178.1 - 0.023 14.4 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 OAG02178.1 - 0.056 12.8 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 OAG02178.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G JAB PF01398.21 OAG02179.1 - 4e-33 113.9 0.0 7.3e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAG02179.1 - 3.7e-13 49.9 0.3 6.9e-13 49.0 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OAG02179.1 - 2.9e-08 33.5 0.0 5.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 OAG02179.1 - 0.057 13.5 0.0 0.21 11.6 0.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) Hist_deacetyl PF00850.19 OAG02180.1 - 2.2e-83 280.3 0.1 4.2e-83 279.3 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain DSPc PF00782.20 OAG02181.1 - 3.9e-26 91.4 0.0 4.5e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 OAG02181.1 - 0.033 14.5 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 OAG02181.1 - 0.2 11.7 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Exo_endo_phos PF03372.23 OAG02182.1 - 7.5e-06 25.6 0.5 1.4e-05 24.7 0.5 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YL1_C PF08265.11 OAG02182.1 - 0.0076 16.0 0.1 0.018 14.8 0.1 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Bestrophin PF01062.21 OAG02183.1 - 2.8e-33 115.6 0.1 6.4e-33 114.4 0.1 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Peptidase_M28 PF04389.17 OAG02184.1 - 3.7e-29 101.8 0.1 5.6e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG02184.1 - 4.2e-06 26.6 0.2 9.7e-06 25.4 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Aldedh PF00171.22 OAG02188.1 - 5.3e-136 453.8 1.1 6.6e-136 453.5 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG02188.1 - 0.00029 20.0 0.0 0.00051 19.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) p450 PF00067.22 OAG02189.1 - 2.2e-55 188.2 0.0 3e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3439 PF11921.8 OAG02190.1 - 0.077 13.0 0.0 0.077 13.0 0.0 5.2 3 1 1 5 5 5 0 Domain of unknown function (DUF3439) Alk_phosphatase PF00245.20 OAG02191.1 - 7.5e-109 364.4 0.2 9.9e-109 364.0 0.2 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OAG02191.1 - 1.6e-05 24.4 0.1 3.2e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Glyco_hydro_36 PF17167.4 OAG02191.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Zn_clus PF00172.18 OAG02193.1 - 8.4e-07 29.0 9.3 1.4e-06 28.3 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L34e PF01199.18 OAG02194.1 - 1.5e-43 147.0 1.7 2.1e-43 146.5 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DZR PF12773.7 OAG02194.1 - 0.02 14.9 0.3 0.032 14.3 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon PROCN PF08083.11 OAG02195.1 - 6.7e-235 779.3 9.0 6.7e-235 779.3 9.0 2.5 3 0 0 3 3 3 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OAG02195.1 - 3e-126 419.7 0.7 5.5e-126 418.8 0.7 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OAG02195.1 - 9.2e-89 295.4 2.3 2.9e-88 293.8 2.3 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OAG02195.1 - 3.3e-78 260.9 1.4 3.3e-78 260.9 1.4 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OAG02195.1 - 1.2e-70 235.8 0.1 2.6e-70 234.7 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 OAG02195.1 - 3.5e-47 159.4 0.0 1.9e-46 157.0 0.0 2.4 3 0 0 3 3 3 1 PROCT (NUC072) domain RRM_4 PF10598.9 OAG02195.1 - 8.1e-47 157.5 0.9 2.1e-46 156.2 0.9 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Glyco_hydro_61 PF03443.14 OAG02196.1 - 1.7e-26 93.5 0.0 5.8e-26 91.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5427 PF10310.9 OAG02198.1 - 2.8e-162 540.9 1.5 3.3e-162 540.7 1.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Ndc1_Nup PF09531.10 OAG02198.1 - 0.5 9.0 5.1 0.83 8.3 5.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2462 PF09495.10 OAG02199.1 - 2.4e-21 76.2 9.7 3.1e-21 75.9 9.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) ILVD_EDD PF00920.21 OAG02200.1 - 1.7e-207 690.1 1.9 2e-207 689.9 1.9 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_S19e PF01090.19 OAG02201.1 - 7.7e-60 200.5 0.2 8.7e-60 200.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e ADH_zinc_N PF00107.26 OAG02202.1 - 1.9e-12 47.3 0.5 3.3e-12 46.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG02202.1 - 6.1e-09 35.7 0.1 7.1e-08 32.3 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 OAG02202.1 - 0.031 13.7 0.1 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YAF2_RYBP PF17219.3 OAG02202.1 - 0.14 11.8 0.1 0.36 10.4 0.1 1.7 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif Amidase PF01425.21 OAG02203.1 - 5e-26 91.7 0.0 7.8e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Amidase LIP PF03583.14 OAG02203.1 - 0.11 11.8 2.0 0.11 11.8 0.4 1.7 2 0 0 2 2 2 0 Secretory lipase Glyco_hydro_43 PF04616.14 OAG02204.1 - 2.2e-52 178.1 3.8 3e-52 177.7 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.11 OAG02204.1 - 0.0071 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) DUF2510 PF10708.9 OAG02204.1 - 0.36 10.6 4.1 0.99 9.2 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) Abhydrolase_6 PF12697.7 OAG02205.1 - 1.7e-18 68.0 0.4 3.3e-18 67.1 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG02205.1 - 5.3e-14 52.5 0.0 1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 OAG02205.1 - 4.9e-11 42.6 0.0 8.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 OAG02205.1 - 2e-10 40.4 0.0 5e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAG02205.1 - 2.9e-05 23.9 0.0 0.00079 19.2 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 OAG02205.1 - 7.6e-05 22.9 0.1 0.00013 22.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Y_phosphatase PF00102.27 OAG02205.1 - 0.0022 17.6 0.0 0.0095 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Lipase_3 PF01764.25 OAG02205.1 - 0.0064 16.4 0.2 0.042 13.7 0.1 2.0 1 1 1 2 2 2 1 Lipase (class 3) PTPlike_phytase PF14566.6 OAG02205.1 - 0.0084 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate LCAT PF02450.15 OAG02205.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Esterase PF00756.20 OAG02205.1 - 0.023 14.4 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 OAG02205.1 - 0.089 11.7 0.0 0.2 10.5 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.13 OAG02205.1 - 0.09 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.16 OAG02205.1 - 0.092 12.5 0.0 5.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 OAG02205.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2237 PF09996.9 OAG02206.1 - 1.7e-12 47.4 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) PUL PF08324.11 OAG02207.1 - 8.5e-66 222.0 3.0 1.2e-65 221.5 3.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OAG02207.1 - 2.2e-44 150.3 0.4 4e-44 149.5 0.4 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OAG02207.1 - 6.1e-35 118.7 4.7 1.5e-07 32.0 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAG02207.1 - 0.00062 19.8 0.0 0.52 10.4 0.0 4.1 3 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Gag_p15 PF08723.10 OAG02207.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Gag protein p15 BTB PF00651.31 OAG02208.1 - 1e-14 54.7 0.3 6.2e-13 48.9 0.1 2.3 2 0 0 2 2 2 2 BTB/POZ domain DUF1854 PF08909.11 OAG02208.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) ATP-synt_E PF05680.12 OAG02210.1 - 0.05 13.9 3.1 0.074 13.4 3.1 1.2 1 0 0 1 1 1 0 ATP synthase E chain TMEM51 PF15345.6 OAG02210.1 - 0.11 12.3 1.8 0.2 11.5 1.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 TMEMspv1-c74-12 PF11044.8 OAG02210.1 - 0.17 11.9 0.4 0.37 10.8 0.4 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein OSTbeta PF15048.6 OAG02210.1 - 0.23 11.6 2.4 0.35 11.0 2.4 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein TMEM174 PF15029.6 OAG02210.1 - 0.28 10.9 1.1 0.47 10.1 1.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 EMC3_TMCO1 PF01956.16 OAG02210.1 - 1.1 8.9 4.0 1.6 8.4 4.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Zn_clus PF00172.18 OAG02212.1 - 6.3e-08 32.6 9.6 1.1e-07 31.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG02212.1 - 0.00018 20.6 0.1 0.00032 19.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ubiquitin PF00240.23 OAG02213.1 - 3.9e-13 48.9 0.0 4.1e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG02213.1 - 0.0017 18.1 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG02213.1 - 0.0076 16.7 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG02213.1 - 0.041 13.8 0.0 0.044 13.7 0.0 1.2 1 1 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain zf-RING_2 PF13639.6 OAG02214.1 - 2e-05 24.8 5.7 6.8e-05 23.1 5.7 2.0 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 OAG02214.1 - 0.00055 19.8 4.2 0.00055 19.8 4.2 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 Cytochrom_CIII PF02085.16 OAG02214.1 - 0.012 15.9 0.5 0.032 14.6 0.5 1.7 1 0 0 1 1 1 0 Class III cytochrome C family FANCL_C PF11793.8 OAG02214.1 - 0.042 14.0 4.7 2.6 8.3 6.6 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain CCDC24 PF15669.5 OAG02214.1 - 0.072 12.9 0.3 0.072 12.9 0.3 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Lzipper-MIP1 PF14389.6 OAG02214.1 - 0.18 12.1 0.0 2.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 zf-HC5HC2H PF13771.6 OAG02214.1 - 0.2 11.9 3.1 0.49 10.7 3.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 OAG02214.1 - 0.21 11.5 11.0 0.028 14.3 6.4 2.0 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.6 OAG02214.1 - 0.21 11.5 2.9 0.58 10.1 2.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 OAG02214.1 - 3.2 7.9 6.1 1.6 8.9 3.2 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger MctB PF11382.8 OAG02217.1 - 0.16 11.7 1.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB DUF1593 PF07632.11 OAG02219.1 - 2.8e-80 269.5 0.0 3.6e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) CoA_binding PF02629.19 OAG02220.1 - 3.9e-21 75.5 0.4 3.9e-21 75.5 0.4 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OAG02220.1 - 6.4e-19 68.3 0.3 1.1e-18 67.5 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAG02220.1 - 3.9e-10 39.7 0.0 7.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OAG02220.1 - 0.012 16.1 0.3 0.068 13.7 0.1 2.2 2 0 0 2 2 2 0 CoA binding domain ATP-grasp_2 PF08442.10 OAG02221.1 - 3.7e-62 209.5 0.0 5.4e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OAG02221.1 - 1.1e-16 61.0 0.8 2.1e-16 60.1 0.8 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OAG02221.1 - 2.5e-11 43.5 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 OAG02221.1 - 0.0032 17.0 0.0 0.0082 15.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Citrate_bind PF16114.5 OAG02221.1 - 0.11 11.9 1.0 0.26 10.8 1.0 1.6 1 1 0 1 1 1 0 ATP citrate lyase citrate-binding Aldedh PF00171.22 OAG02222.1 - 1.1e-179 597.8 0.1 1.3e-179 597.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TMEM132D_C PF15706.5 OAG02223.1 - 0.17 11.6 1.0 2.2 8.1 0.4 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Aldedh PF00171.22 OAG02224.1 - 5.3e-158 526.3 0.4 6e-158 526.1 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG02224.1 - 0.0001 21.8 0.0 0.0011 18.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF1513 PF07433.11 OAG02224.1 - 0.081 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) adh_short_C2 PF13561.6 OAG02225.1 - 1.6e-58 198.0 0.0 2e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG02225.1 - 1.2e-44 152.1 0.0 1.5e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG02225.1 - 1.4e-05 25.1 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG02225.1 - 0.0037 17.2 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG02225.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 OAG02225.1 - 0.027 14.5 1.1 0.045 13.8 1.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PQ-loop PF04193.14 OAG02226.1 - 4.7e-23 80.7 9.5 8.7e-22 76.7 0.4 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 OAG02226.1 - 0.017 15.1 1.2 0.017 15.1 1.2 2.4 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF4535 PF15054.6 OAG02226.1 - 0.13 12.0 0.8 0.43 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) DUF981 PF06168.11 OAG02226.1 - 5.2 6.9 11.6 2.7 7.9 6.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF981) E1-E2_ATPase PF00122.20 OAG02227.1 - 1.1e-34 119.5 0.1 1.1e-34 119.5 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG02227.1 - 5.8e-30 105.1 0.1 1e-29 104.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG02227.1 - 6.7e-10 39.3 0.1 1.8e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 OAG02227.1 - 0.0038 17.0 0.1 0.11 12.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Methyltransf_18 PF12847.7 OAG02227.1 - 0.068 13.1 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Ldi PF18566.1 OAG02228.1 - 5.8e-76 256.0 0.0 8.2e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase Phage_holin_3_6 PF07332.11 OAG02228.1 - 3.1 7.9 12.7 92 3.1 12.7 2.5 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Fungal_trans PF04082.18 OAG02229.1 - 8.8e-25 87.2 1.0 1.5e-24 86.5 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02229.1 - 1.1e-09 38.2 8.7 3.5e-09 36.6 8.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 OAG02230.1 - 1.4e-25 90.3 0.0 3.5e-25 89.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAG02230.1 - 4.4e-07 29.8 0.0 2.5e-05 24.2 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 OAG02230.1 - 8.1e-05 22.9 0.4 0.00092 19.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 OAG02230.1 - 0.00018 21.0 0.0 0.026 14.0 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 OAG02230.1 - 0.00048 20.5 0.1 0.002 18.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG02230.1 - 0.0006 19.8 0.3 0.0047 16.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAG02230.1 - 0.001 18.3 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAG02230.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 OAG02230.1 - 0.0065 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 OAG02230.1 - 0.0098 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OAG02230.1 - 0.012 15.3 0.2 0.043 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG02230.1 - 0.035 13.8 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 OAG02230.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAG02230.1 - 0.099 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 OAG02230.1 - 0.13 12.8 1.0 0.67 10.5 0.0 2.4 2 1 1 3 3 3 0 ABC transporter Bac_DnaA PF00308.18 OAG02230.1 - 0.14 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 OAG02230.1 - 0.2 10.9 0.2 0.56 9.5 0.1 1.7 1 1 0 1 1 1 0 KaiC Fungal_trans PF04082.18 OAG02231.1 - 2.2e-25 89.2 0.1 3.7e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02231.1 - 6.6e-06 26.1 10.4 1.1e-05 25.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MaoC_dehydrat_N PF13452.6 OAG02232.1 - 0.033 14.3 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase ADH_zinc_N PF00107.26 OAG02233.1 - 7.1e-25 87.5 0.1 1.4e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG02233.1 - 1.6e-20 73.0 1.7 1.6e-20 73.0 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG02233.1 - 1.2e-11 44.5 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG02233.1 - 9e-05 23.5 0.0 0.00018 22.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG02233.1 - 0.042 13.1 0.7 0.086 12.1 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NADH_4Fe-4S PF10589.9 OAG02233.1 - 0.061 13.4 0.3 0.2 11.7 0.3 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PALP PF00291.25 OAG02233.1 - 0.072 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Redoxin PF08534.10 OAG02233.1 - 0.1 12.3 0.1 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 Redoxin Glyco_hydro_43 PF04616.14 OAG02234.1 - 3.7e-31 108.5 1.5 4.5e-31 108.2 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GIT_SHD PF08518.11 OAG02235.1 - 3.6e-22 77.7 7.3 9.2e-12 44.4 0.6 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT SHE3 PF17078.5 OAG02235.1 - 0.0015 18.3 18.8 0.18 11.5 1.3 2.4 2 0 0 2 2 2 2 SWI5-dependent HO expression protein 3 Phage_GP20 PF06810.11 OAG02235.1 - 0.014 15.2 18.7 1.9 8.3 0.0 4.0 1 1 3 4 4 4 0 Phage minor structural protein GP20 ZapB PF06005.12 OAG02235.1 - 0.015 15.7 27.3 0.53 10.8 0.1 4.1 3 1 0 3 3 3 0 Cell division protein ZapB CLZ PF16526.5 OAG02235.1 - 0.17 12.3 24.2 0.66 10.4 2.0 5.0 4 1 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 OAG02235.1 - 0.26 11.3 30.9 4.2 7.4 5.7 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 OAG02235.1 - 0.28 10.7 27.6 0.009 15.6 6.5 2.9 1 1 0 2 2 2 0 Intermediate filament protein Rootletin PF15035.6 OAG02235.1 - 0.36 10.8 30.4 0.62 10.1 25.9 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 OAG02235.1 - 0.43 11.2 23.2 1.7 9.3 1.8 4.7 3 1 1 4 4 4 0 SlyX Tropomyosin_1 PF12718.7 OAG02235.1 - 0.82 9.8 42.7 0.28 11.3 7.0 2.7 2 1 1 3 3 2 0 Tropomyosin like LPP PF04728.13 OAG02235.1 - 0.83 10.1 11.8 0.45 10.9 2.2 4.0 4 0 0 4 4 3 0 Lipoprotein leucine-zipper Spc7 PF08317.11 OAG02235.1 - 0.99 8.2 31.9 2 7.2 13.0 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein THP2 PF09432.10 OAG02235.1 - 1.2 9.2 8.7 0.18 11.8 2.6 2.6 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF5082 PF16888.5 OAG02235.1 - 1.8 8.9 18.4 0.49 10.7 10.4 3.7 3 1 0 3 3 2 0 Domain of unknown function (DUF5082) CENP-F_leu_zip PF10473.9 OAG02235.1 - 1.8 8.6 33.1 0.85 9.6 11.4 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 OAG02235.1 - 1.8 8.3 33.2 0.56 10.0 16.1 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 OAG02235.1 - 2.3 8.3 14.1 7.6 6.6 1.9 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OAG02235.1 - 3.3 7.0 28.3 0.32 10.3 15.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 OAG02235.1 - 4.8 5.7 22.1 0.93 8.0 7.7 2.1 1 1 1 2 2 2 0 AAA domain APG6_N PF17675.1 OAG02235.1 - 5 7.7 39.6 4.3 7.9 15.0 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 OAG02235.1 - 5.2 7.1 22.9 0.43 10.6 2.0 4.4 3 1 0 3 3 3 0 Prefoldin subunit DUF3138 PF11336.8 OAG02235.1 - 6.3 5.3 7.3 11 4.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) TolA_bind_tri PF16331.5 OAG02235.1 - 6.4 6.9 22.4 0.059 13.4 0.9 3.9 3 1 0 3 3 3 0 TolA binding protein trimerisation Med9 PF07544.13 OAG02235.1 - 7.6 6.7 17.0 52 4.0 4.1 4.5 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ING PF12998.7 OAG02236.1 - 4.9e-22 78.4 3.7 4.9e-22 78.4 3.7 1.5 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAG02236.1 - 9.4e-06 25.4 10.4 1.5e-05 24.8 10.4 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OAG02236.1 - 0.0056 16.9 0.6 0.011 16.0 0.6 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain TFIIA PF03153.13 OAG02236.1 - 0.015 15.4 10.4 0.0084 16.2 8.5 1.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SWIM PF04434.17 OAG02236.1 - 0.089 12.5 0.7 0.17 11.6 0.7 1.4 1 0 0 1 1 1 0 SWIM zinc finger Cdh1_DBD_1 PF18196.1 OAG02236.1 - 0.8 10.0 5.0 0.36 11.2 0.4 2.6 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Hist_deacetyl PF00850.19 OAG02237.1 - 6.5e-74 249.2 0.0 8.9e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Fungal_trans PF04082.18 OAG02238.1 - 3.4e-14 52.5 0.0 7.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02238.1 - 1.2e-09 38.1 12.5 2.7e-09 37.0 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 OAG02239.1 - 1.5e-36 125.4 0.0 1.9e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG02239.1 - 2.3e-10 40.2 0.0 3.2e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 OAG02239.1 - 0.0085 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OAG02239.1 - 0.029 14.5 0.2 0.057 13.6 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1241 PF06840.11 OAG02241.1 - 0.05 13.2 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) SlyX PF04102.12 OAG02241.1 - 0.13 12.9 1.6 0.19 12.4 1.6 1.2 1 0 0 1 1 1 0 SlyX OsmC PF02566.19 OAG02242.1 - 3.7e-14 53.0 0.0 7.2e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein FMN_dh PF01070.18 OAG02243.1 - 2.2e-125 418.3 0.1 2.7e-125 418.0 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG02243.1 - 1.2e-08 34.3 0.0 2.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG02243.1 - 1.3e-06 27.8 0.0 2.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAG02243.1 - 1.6e-05 24.5 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAG02243.1 - 0.00049 19.6 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 OAG02243.1 - 0.052 12.9 0.2 0.3 10.3 0.0 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.19 OAG02243.1 - 0.077 12.4 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Kelch_1 PF01344.25 OAG02244.1 - 1.5e-28 98.1 13.8 5.8e-05 22.6 0.3 7.2 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 OAG02244.1 - 6.4e-21 73.9 21.7 1.9e-05 24.8 0.2 7.2 3 3 4 7 7 7 6 Kelch motif Kelch_4 PF13418.6 OAG02244.1 - 8.4e-21 73.7 15.2 1.1e-06 28.5 0.0 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG02244.1 - 5.5e-14 51.5 8.3 0.21 11.6 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 OAG02244.1 - 1.1e-13 50.8 5.3 0.23 11.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OAG02244.1 - 1.8e-09 37.6 16.2 0.0043 17.3 0.2 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain PHO4 PF01384.20 OAG02245.1 - 2.2e-107 359.0 13.9 2.6e-107 358.8 13.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 OAG02245.1 - 0.0081 16.5 2.2 0.026 14.9 0.2 2.9 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Glycophorin_A PF01102.18 OAG02245.1 - 0.09 13.0 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Glycophorin A Glyco_hydro_3 PF00933.21 OAG02246.1 - 4.8e-44 151.0 0.0 6.9e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAG02246.1 - 4.3e-10 39.9 0.0 7.5e-08 32.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain FAD_binding_4 PF01565.23 OAG02247.1 - 4.1e-25 88.1 0.1 8e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG02247.1 - 7.6e-20 71.6 0.0 1.1e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain SKICH PF17751.1 OAG02247.1 - 0.021 15.4 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 SKICH domain Phage_CP76 PF06892.11 OAG02247.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) FliM PF02154.15 OAG02247.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar motor switch protein FliM YjeF_N PF03853.15 OAG02250.1 - 1.4e-34 119.4 0.0 1.7e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 OAG02250.1 - 0.02 15.0 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein ABC_sub_bind PF04392.12 OAG02250.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein Ribosomal_S16 PF00886.19 OAG02251.1 - 2.6e-25 88.2 0.1 3.7e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.18 OAG02252.1 - 1.5e-94 317.0 13.2 2.2e-94 316.5 13.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ORMDL PF04061.14 OAG02252.1 - 0.91 9.3 4.6 0.5 10.2 0.1 2.5 3 0 0 3 3 3 0 ORMDL family EMP70 PF02990.16 OAG02252.1 - 1.4 7.5 8.9 2.9 6.4 6.9 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 DUF2417 PF10329.9 OAG02252.1 - 6.9 6.0 12.3 0.98 8.8 0.2 3.7 3 1 0 3 3 3 0 Region of unknown function (DUF2417) Dynactin_p22 PF07426.11 OAG02253.1 - 1.4e-09 38.0 1.8 1.4e-09 38.0 1.8 1.3 2 0 0 2 2 2 1 Dynactin subunit p22 Rubrerythrin PF02915.17 OAG02253.1 - 0.002 18.5 1.5 0.6 10.5 0.1 2.7 1 1 1 2 2 2 2 Rubrerythrin Sec20 PF03908.13 OAG02253.1 - 0.12 12.3 0.6 1.3 9.0 0.1 2.4 2 1 0 2 2 2 0 Sec20 SH3_1 PF00018.28 OAG02256.1 - 1.1e-09 37.7 0.1 2.2e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG02256.1 - 1.9e-07 30.8 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG02256.1 - 1.4e-06 27.9 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2569 PF10754.9 OAG02256.1 - 0.16 12.4 2.9 0.29 11.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) 7tm_6 PF02949.20 OAG02256.1 - 0.56 9.2 7.3 0.29 10.2 1.8 2.0 1 1 1 2 2 2 0 7tm Odorant receptor DUF4149 PF13664.6 OAG02256.1 - 5.8 7.3 7.0 76 3.7 7.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) Peptidase_S10 PF00450.22 OAG02257.1 - 1.8e-16 60.6 0.3 2.2e-16 60.3 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase AA_permease_2 PF13520.6 OAG02259.1 - 8.2e-70 235.8 40.2 1e-69 235.4 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG02259.1 - 3.4e-14 52.3 37.2 4.5e-14 51.9 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease Dioxygenase_C PF00775.21 OAG02261.1 - 1.3e-07 31.2 0.1 2.1e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase SH3_1 PF00018.28 OAG02262.1 - 7e-10 38.4 0.0 1.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG02262.1 - 8.1e-10 38.4 0.1 1.8e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG02262.1 - 2.7e-06 27.0 0.0 6.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.13 OAG02264.1 - 8.4e-80 266.8 0.0 9.9e-80 266.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PRIMA1 PF16101.5 OAG02264.1 - 1.9 8.5 10.3 3.2 7.8 10.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CorA PF01544.18 OAG02265.1 - 2e-05 24.0 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_61 PF03443.14 OAG02266.1 - 3.8e-48 164.2 0.1 4.8e-48 163.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4611 PF15387.6 OAG02267.1 - 0.049 13.8 2.0 0.12 12.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Nepo_coat_N PF03689.15 OAG02267.1 - 0.098 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Carboxyl_trans PF01039.22 OAG02268.1 - 1.9e-136 455.6 0.1 2.6e-136 455.2 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Patatin PF01734.22 OAG02268.1 - 0.082 13.1 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase Macro_2 PF14519.6 OAG02269.1 - 0.00025 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.21 OAG02269.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 1 0 1 1 1 0 Macro domain adh_short PF00106.25 OAG02270.1 - 1.2e-27 96.7 0.0 1.5e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02270.1 - 9.8e-20 71.1 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG02270.1 - 0.00037 20.4 0.0 0.0025 17.8 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 OAG02271.1 - 1.4e-63 214.6 0.2 1.6e-63 214.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG02271.1 - 3e-51 173.7 0.8 3.8e-51 173.3 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG02271.1 - 8.5e-14 51.9 1.8 1.1e-13 51.4 1.8 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG02271.1 - 0.037 13.9 0.2 0.062 13.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AtuA PF07287.11 OAG02272.1 - 1.3e-44 152.4 0.1 1.3e-41 142.6 0.1 2.1 1 1 1 2 2 2 2 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 OAG02273.1 - 2.6e-21 75.9 0.6 4.3e-21 75.1 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02273.1 - 0.00011 22.3 7.5 0.00019 21.5 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Malic_M PF03949.15 OAG02274.1 - 2.5e-91 305.5 0.0 3.4e-91 305.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAG02274.1 - 4.5e-67 225.4 0.0 6.6e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Chitin_bind_1 PF00187.19 OAG02275.1 - 0.00011 22.5 16.9 0.0002 21.7 16.9 1.4 1 0 0 1 1 1 1 Chitin recognition protein Phage_Integr_2 PF13009.6 OAG02275.1 - 0.066 12.3 0.7 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Putative phage integrase DUF4248 PF14053.6 OAG02276.1 - 0.097 12.7 0.3 2.2 8.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) HET-s_218-289 PF11558.8 OAG02276.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Het-s 218-289 V_ATPase_I PF01496.19 OAG02276.1 - 5.3 4.8 11.7 0.98 7.3 0.1 2.3 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 OAG02276.1 - 6.5 7.1 9.3 2.8 8.3 2.2 3.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPP1 PF05630.11 OAG02277.1 - 4.5e-61 206.4 0.0 5.2e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF4286 PF14114.6 OAG02278.1 - 0.054 14.0 0.1 5.2 7.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4286) Metallophos PF00149.28 OAG02279.1 - 1.8e-11 44.9 0.6 4.6e-11 43.6 0.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG02279.1 - 3.5e-07 30.5 0.0 2.1e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GATA PF00320.27 OAG02279.1 - 1.6 8.4 4.0 5.9 6.6 0.4 2.5 2 0 0 2 2 2 0 GATA zinc finger DUF1593 PF07632.11 OAG02280.1 - 1.5e-89 299.8 0.0 2e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 OAG02280.1 - 9.7e-05 21.3 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 REJ domain Transp_cyt_pur PF02133.15 OAG02283.1 - 5.9e-50 170.3 34.8 7.4e-50 170.0 34.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NACHT PF05729.12 OAG02284.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NepR PF18557.1 OAG02285.1 - 0.077 12.7 0.3 4.7 6.9 0.0 3.0 3 0 0 3 3 3 0 Anti-sigma factor NepR ADH_zinc_N PF00107.26 OAG02286.1 - 1.7e-10 41.0 0.1 2.9e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG02286.1 - 1.9e-08 34.2 0.0 5.5e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MAF_flag10 PF01973.18 OAG02286.1 - 0.14 11.9 0.0 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF115 MFS_1 PF07690.16 OAG02287.1 - 4.5e-32 111.3 37.2 4.1e-31 108.2 21.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG02287.1 - 4.8e-28 98.2 19.8 5.1e-26 91.5 19.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.19 OAG02287.1 - 0.0033 16.3 9.6 0.0062 15.4 9.6 1.5 1 0 0 1 1 1 1 LacY proton/sugar symporter DUF4046 PF13255.6 OAG02287.1 - 0.086 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) DUF4564 PF15169.6 OAG02287.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Peptidase_A8 PF01252.18 OAG02287.1 - 3.9 7.7 7.5 0.35 11.1 1.8 2.3 2 1 0 2 2 2 0 Signal peptidase (SPase) II Cation_ATPase_C PF00689.21 OAG02287.1 - 6.7 6.4 9.6 12 5.6 3.4 2.6 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Peptidase_A4 PF01828.17 OAG02289.1 - 6.5e-84 280.6 16.9 7.7e-84 280.3 16.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family dCMP_cyt_deam_2 PF08211.12 OAG02289.1 - 0.039 14.2 0.1 0.064 13.5 0.1 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region PRIMA1 PF16101.5 OAG02290.1 - 7.1 6.7 12.4 26 4.9 12.0 1.9 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 BNR_2 PF13088.6 OAG02291.1 - 0.00014 21.2 0.2 0.0013 18.1 0.1 2.5 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OAG02291.1 - 0.0002 20.9 3.3 0.2 11.8 0.4 3.6 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 OAG02291.1 - 0.0026 16.6 1.4 0.047 12.5 1.1 2.9 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, Glyco_hydro_61 PF03443.14 OAG02293.1 - 6e-65 219.0 2.3 7.4e-65 218.7 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Mid2 PF04478.12 OAG02294.1 - 8.3e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Glyco_hydro_71 PF03659.14 OAG02295.1 - 6.7e-91 304.9 0.0 8.1e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_99 PF16317.5 OAG02295.1 - 0.0022 17.2 0.0 0.0066 15.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 CobU PF02283.16 OAG02296.1 - 2.5 7.7 7.0 1.7 8.2 0.3 2.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TFR_dimer PF04253.15 OAG02297.1 - 6.2e-29 100.6 0.1 9.7e-29 99.9 0.1 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG02297.1 - 4.9e-20 72.1 0.0 8e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG02297.1 - 8.2e-09 35.4 1.2 3.1e-08 33.5 0.2 2.2 2 0 0 2 2 2 1 PA domain RBM39linker PF15519.6 OAG02302.1 - 0.031 15.3 0.2 0.1 13.7 0.0 1.8 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Slx4 PF09494.10 OAG02303.1 - 7.9e-17 61.0 3.1 7e-16 57.9 3.1 2.3 1 1 0 1 1 1 1 Slx4 endonuclease Peptidase_C15 PF01470.17 OAG02304.1 - 9.3e-20 71.7 0.0 1.8e-13 51.1 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase SCAN PF02023.17 OAG02305.1 - 0.056 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 SCAN domain Gpr1_Fun34_YaaH PF01184.19 OAG02306.1 - 4.1e-24 85.3 14.8 5.1e-24 85.0 14.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Zn_clus PF00172.18 OAG02307.1 - 1.6e-07 31.4 15.4 3.3e-07 30.3 15.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 OAG02308.1 - 2.6e-142 474.8 41.4 3.3e-142 474.5 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG02308.1 - 4.9e-41 140.9 41.8 6.7e-41 140.5 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG02309.1 - 5.6e-103 345.1 37.2 6.8e-103 344.8 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG02309.1 - 6.5e-23 81.2 41.7 7.6e-23 81.0 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_9_N PF15420.6 OAG02310.1 - 5.6 6.9 10.7 0.64 10.0 4.3 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Glyco_hydro_115 PF15979.5 OAG02312.1 - 1.5e-138 461.9 8.5 1.5e-138 461.9 8.5 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 OAG02312.1 - 1.8e-55 187.4 0.0 4.8e-55 186.0 0.0 1.8 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain S_layer_C PF05124.12 OAG02312.1 - 0.0021 18.1 0.2 0.0037 17.3 0.2 1.4 1 0 0 1 1 1 1 S-layer like family, C-terminal region DUF3390 PF11870.8 OAG02312.1 - 0.29 11.5 2.9 11 6.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3390) FAD_binding_7 PF03441.14 OAG02313.1 - 8.8e-78 260.4 0.5 1.4e-77 259.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG02313.1 - 2.1e-37 128.6 0.0 3.9e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Peptidase_S9 PF00326.21 OAG02316.1 - 1.1e-44 152.4 2.4 1.8e-44 151.8 2.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OAG02316.1 - 7.2e-06 25.8 5.0 0.00099 19.0 0.1 4.0 3 1 0 3 3 3 2 WD40-like Beta Propeller Repeat Esterase_phd PF10503.9 OAG02316.1 - 0.00053 19.6 0.0 0.0015 18.1 0.0 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase DUF2436 PF10365.9 OAG02316.1 - 0.088 12.5 0.2 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2436) PTCRA PF15028.6 OAG02316.1 - 0.15 11.7 1.7 0.41 10.3 1.3 1.9 1 1 0 1 1 1 0 Pre-T-cell antigen receptor MFS_1 PF07690.16 OAG02317.1 - 1e-36 126.6 30.7 4.2e-28 98.3 1.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG02317.1 - 2.1e-12 46.6 12.6 1.1e-10 41.0 0.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAG02317.1 - 0.046 12.1 5.9 0.033 12.6 0.5 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF498 PF04430.14 OAG02319.1 - 2.4e-29 101.6 0.0 3.7e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF4208 PF13907.6 OAG02320.1 - 3.9e-07 30.4 0.0 8.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Pkinase PF00069.25 OAG02321.1 - 3.8e-69 233.0 0.0 8e-69 231.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG02321.1 - 4.7e-33 114.6 0.0 2.1e-31 109.1 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAG02321.1 - 0.00021 21.0 0.3 0.00038 20.1 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAG02321.1 - 0.0021 18.0 0.0 0.1 12.5 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG02321.1 - 0.003 16.9 0.4 2.3 7.4 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 OAG02321.1 - 0.0067 15.2 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Ribonuc_L-PSP PF01042.21 OAG02327.1 - 9.4e-21 74.1 0.0 1.1e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Myb_DNA-bind_6 PF13921.6 OAG02328.1 - 1.6e-05 25.1 0.1 0.008 16.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAG02328.1 - 0.00035 20.7 1.1 0.00078 19.6 0.3 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Hydin_ADK PF17213.3 OAG02328.1 - 0.34 11.2 3.4 0.51 10.6 3.4 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Myb_DNA-binding PF00249.31 OAG02329.1 - 5.4e-14 52.1 1.9 2.9e-08 33.8 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG02329.1 - 7.8e-08 32.4 2.8 1.5e-05 25.1 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG02329.1 - 0.025 14.5 0.4 0.053 13.4 0.4 1.6 1 0 0 1 1 1 0 Myb DNA-binding like Ndc1_Nup PF09531.10 OAG02329.1 - 3.4 6.2 9.2 4.6 5.8 9.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Myb_DNA-bind_6 PF13921.6 OAG02331.1 - 6.9e-13 48.6 0.1 2.4e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAG02331.1 - 2.9e-12 46.6 0.1 6.9e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAG02331.1 - 0.26 11.5 1.1 6.4 7.0 0.4 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Orexin PF02072.15 OAG02332.1 - 0.12 12.3 0.6 0.16 11.9 0.6 1.2 1 0 0 1 1 1 0 Prepro-orexin zf-RING_2 PF13639.6 OAG02333.1 - 0.00057 20.2 7.5 0.00057 20.2 7.5 2.0 2 1 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OAG02333.1 - 0.004 17.0 5.0 0.013 15.4 5.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG02333.1 - 0.0045 16.9 5.4 0.008 16.1 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG02333.1 - 0.014 15.3 4.3 0.035 14.0 4.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG02333.1 - 0.052 13.6 6.6 0.11 12.6 6.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG02333.1 - 0.11 12.4 7.6 0.39 10.6 7.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG02333.1 - 0.63 9.9 6.0 0.31 10.9 2.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3624 PF12292.8 OAG02333.1 - 2.6 8.5 6.9 1.2 9.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) HRXXH PF13933.6 OAG02334.1 - 8e-104 346.5 0.1 1.3e-103 345.9 0.0 1.3 2 0 0 2 2 2 1 Putative peptidase family Aspzincin_M35 PF14521.6 OAG02334.1 - 3.5e-05 24.4 0.0 0.00012 22.6 0.0 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Zip PF02535.22 OAG02335.1 - 9.6e-38 130.2 21.3 9.6e-38 130.2 21.3 2.3 2 1 0 2 2 2 1 ZIP Zinc transporter PD40 PF07676.12 OAG02336.1 - 0.019 14.9 0.1 3.7 7.6 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat F-box PF00646.33 OAG02337.1 - 2e-05 24.3 1.2 9.1e-05 22.2 0.4 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG02337.1 - 0.011 15.6 0.5 0.032 14.1 0.1 2.0 2 0 0 2 2 2 0 F-box-like SKG6 PF08693.10 OAG02338.1 - 0.00017 20.9 1.7 0.00033 20.0 1.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OAG02338.1 - 0.023 15.6 0.0 0.045 14.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OAG02338.1 - 0.025 14.3 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gram_pos_anchor PF00746.21 OAG02338.1 - 0.026 14.5 0.7 0.057 13.4 0.7 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif FeoB_associated PF12669.7 OAG02338.1 - 0.037 14.4 1.2 0.096 13.1 1.2 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2207 PF09972.9 OAG02338.1 - 0.06 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mucin15 PF15672.5 OAG02338.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 DAP10 PF07213.11 OAG02338.1 - 0.09 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Syndecan PF01034.20 OAG02338.1 - 0.1 12.5 0.3 0.24 11.3 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain RIFIN PF02009.16 OAG02338.1 - 0.24 11.3 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Rifin TMEM89 PF15098.6 OAG02338.1 - 0.5 10.5 2.4 2.6 8.2 2.0 2.0 2 0 0 2 2 2 0 TMEM89 protein family SOG2 PF10428.9 OAG02338.1 - 1.1 8.4 4.0 1.4 8.0 4.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_76 PF03663.14 OAG02339.1 - 4.5e-21 75.8 4.3 1.5e-14 54.3 0.7 3.6 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG02339.1 - 0.0056 15.8 0.1 0.015 14.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 IBN_N PF03810.19 OAG02340.1 - 2.4e-14 53.0 0.3 1e-13 50.9 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAG02340.1 - 4.2e-05 23.6 0.9 0.00021 21.4 0.0 2.7 2 1 0 2 2 2 1 Exportin 1-like protein Pex2_Pex12 PF04757.14 OAG02341.1 - 1.4e-37 129.5 2.0 1.9e-37 129.0 2.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 OAG02341.1 - 0.00022 21.3 4.7 0.00042 20.4 4.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAG02341.1 - 0.021 14.8 1.6 0.075 13.1 1.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG02341.1 - 0.096 12.6 1.2 0.22 11.4 1.2 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG02341.1 - 7.3 6.5 9.9 4 7.4 5.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 OAG02342.1 - 1.1e-06 28.9 1.9 0.005 17.6 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG02342.1 - 5.4e-05 23.4 3.1 0.0026 18.1 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 OAG02342.1 - 0.0046 17.8 0.3 0.0096 16.8 0.3 1.6 1 1 0 1 1 1 1 Ima1 N-terminal domain zf-C2H2_6 PF13912.6 OAG02342.1 - 0.027 14.4 1.4 0.056 13.5 0.5 1.9 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG02342.1 - 0.063 13.1 0.5 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OAG02342.1 - 0.22 11.9 2.1 4.4 7.7 0.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Peptidase_C12 PF01088.21 OAG02343.1 - 7.9e-16 58.4 0.0 1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_S28 PF05577.12 OAG02345.1 - 1.1e-51 176.1 0.0 3e-51 174.6 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 6PGD PF00393.19 OAG02347.1 - 3.8e-84 282.5 0.0 7.1e-84 281.6 0.0 1.4 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG02347.1 - 1.8e-33 115.9 0.0 3.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAG02347.1 - 6.7e-07 29.4 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAG02347.1 - 0.0038 17.2 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 OAG02347.1 - 0.005 16.4 0.0 0.043 13.4 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OAG02347.1 - 0.013 16.1 1.3 0.027 15.0 0.0 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OAG02347.1 - 0.057 13.7 0.0 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 OAG02347.1 - 0.18 11.1 0.6 5.6 6.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.22 OAG02349.1 - 1e-14 54.0 0.0 1.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAG02349.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF1996 PF09362.10 OAG02351.1 - 6.7e-81 271.7 3.2 8.2e-81 271.4 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-RING_2 PF13639.6 OAG02353.1 - 0.012 16.0 3.3 0.023 15.0 3.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 OAG02353.1 - 1.5 8.9 4.3 3.2 7.9 4.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Cu_bind_like PF02298.17 OAG02354.1 - 0.16 12.0 0.2 0.53 10.3 0.2 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain RNase_PH PF01138.21 OAG02356.1 - 1.3e-37 129.2 0.1 2.1e-37 128.5 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.23 OAG02357.1 - 3.9e-52 177.1 0.3 1.1e-51 175.6 0.3 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG02357.1 - 1.4e-20 73.7 0.0 1.9e-17 63.6 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 OAG02357.1 - 3.1e-18 65.7 0.1 1.4e-17 63.6 0.1 2.3 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.15 OAG02357.1 - 3.6e-07 30.3 0.0 2.1e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG02357.1 - 1.7e-05 24.2 0.1 3.6e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 OAG02357.1 - 0.005 15.8 0.9 0.61 8.9 0.0 2.7 3 0 0 3 3 3 2 P-loop containing NTP hydrolase pore-1 NAS PF03059.16 OAG02358.1 - 2e-66 224.2 0.0 2.3e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 OAG02358.1 - 7.5e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02358.1 - 0.087 13.5 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Amidohydro_3 PF07969.11 OAG02359.1 - 7.4e-68 230.1 0.0 9.4e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG02359.1 - 1.3e-07 31.2 0.2 1.6e-06 27.7 0.1 2.5 2 1 0 2 2 2 1 Amidohydrolase family Peptidase_U32_C PF16325.5 OAG02359.1 - 0.14 12.5 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain CorA PF01544.18 OAG02360.1 - 7.2e-14 51.8 0.0 1.8e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fungal_TACC PF12709.7 OAG02360.1 - 0.19 12.2 3.9 0.37 11.2 0.4 2.4 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Csm1_N PF18504.1 OAG02360.1 - 2.6 8.4 4.8 24 5.4 1.0 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain PhyH PF05721.13 OAG02361.1 - 4.6e-07 30.3 0.0 1.1e-06 29.1 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG02361.1 - 5.2e-05 22.2 0.1 0.22 10.2 0.1 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 OAG02362.1 - 7.4e-76 255.8 18.8 1.2e-75 255.1 18.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG02362.1 - 7.4e-19 67.9 21.7 7.4e-19 67.9 21.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Herpes_LMP1 PF05297.11 OAG02362.1 - 0.013 14.7 0.7 0.021 14.1 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VIT1 PF01988.19 OAG02363.1 - 2.1e-63 214.1 3.2 2.4e-63 213.9 3.2 1.0 1 0 0 1 1 1 1 VIT family DUF2465 PF10239.9 OAG02363.1 - 0.072 12.3 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) DUF1146 PF06612.11 OAG02363.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) DUF3165 PF11364.8 OAG02363.1 - 0.23 11.8 0.7 0.41 11.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) Pet191_N PF10203.9 OAG02364.1 - 1e-26 93.0 3.5 1.3e-26 92.6 3.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 OAG02364.1 - 0.055 13.5 1.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 OAG02364.1 - 3.4 7.8 8.3 34 4.6 2.3 3.0 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydrolase_1 PF00561.20 OAG02365.1 - 2.9e-23 82.8 0.1 8.2e-23 81.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OAG02365.1 - 1.4e-20 72.6 0.1 3.1e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 OAG02365.1 - 4.1e-05 23.0 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 OAG02365.1 - 0.0006 19.5 0.1 0.78 9.4 0.0 2.8 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Glyco_hydro_43 PF04616.14 OAG02366.1 - 7.8e-49 166.5 0.7 1e-48 166.2 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG02366.1 - 2.3e-30 105.8 0.0 3.3e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DHHC PF01529.20 OAG02369.1 - 1.5e-28 99.5 4.7 1.5e-28 99.5 4.7 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1772 PF08592.11 OAG02369.1 - 0.0065 16.8 0.5 2.4 8.5 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) Homeobox_KN PF05920.11 OAG02370.1 - 9.1e-19 67.1 0.4 1.4e-18 66.5 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAG02370.1 - 1.3e-10 41.0 0.5 1.9e-10 40.4 0.5 1.2 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OAG02370.1 - 0.0016 17.9 2.7 0.003 17.0 0.2 2.1 1 1 1 2 2 2 1 Homeodomain leucine-zipper encoding, Homez SprT-like PF10263.9 OAG02373.1 - 8.8e-10 38.4 0.1 1.5e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Mpv17_PMP22 PF04117.12 OAG02374.1 - 5.6e-12 45.7 1.7 3.3e-11 43.2 1.2 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family NADH_oxidored PF08040.11 OAG02374.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit Fungal_trans_2 PF11951.8 OAG02376.1 - 2.7e-11 42.9 3.8 2.7e-11 42.9 3.8 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02376.1 - 1e-05 25.5 13.0 1.9e-05 24.7 12.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 OAG02376.1 - 0.00031 20.4 1.5 0.00074 19.2 1.5 1.6 1 0 0 1 1 1 1 Integrin plexin domain Ribosomal_S30 PF04758.14 OAG02377.1 - 1.2e-29 102.2 7.8 1.4e-29 102.1 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Gly_transf_sug PF04488.15 OAG02379.1 - 3.7e-15 56.3 0.0 7.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TFIIA PF03153.13 OAG02380.1 - 4.7 7.1 12.8 5.4 6.9 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAP PF07174.11 OAG02380.1 - 6.1 6.2 16.2 8.2 5.8 16.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Presenilin PF01080.17 OAG02380.1 - 6.2 5.5 5.7 8.2 5.1 5.7 1.2 1 0 0 1 1 1 0 Presenilin NACHT PF05729.12 OAG02383.1 - 1.3e-08 34.9 0.0 5.2e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain NACHT_N PF17100.5 OAG02383.1 - 5.2e-08 33.0 0.3 1e-07 32.1 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_22 PF13401.6 OAG02383.1 - 4.5e-06 27.0 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG02383.1 - 6.6e-06 26.6 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain UspB PF10625.9 OAG02383.1 - 0.027 14.4 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Universal stress protein B (UspB) AAA PF00004.29 OAG02383.1 - 0.027 14.9 0.2 0.42 11.0 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG02383.1 - 0.14 12.6 0.0 0.51 10.7 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 OAG02383.1 - 0.19 11.8 1.7 24 4.9 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain Ank_2 PF12796.7 OAG02384.1 - 2.2e-12 47.4 0.0 8.4e-11 42.3 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG02384.1 - 7.1e-12 45.6 0.0 2.9e-06 27.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG02384.1 - 8.5e-08 32.3 0.0 0.042 14.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG02384.1 - 1.5e-07 31.6 0.0 0.00064 20.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG02384.1 - 6e-07 29.3 0.0 0.00081 19.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Cerato-platanin PF07249.12 OAG02385.1 - 1.6e-05 25.0 0.2 2.6e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Cerato-platanin Peptidase_M16_C PF05193.21 OAG02387.1 - 2.9e-54 183.9 0.0 9.1e-54 182.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG02387.1 - 4.2e-40 137.1 0.0 1.6e-39 135.3 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) FHA PF00498.26 OAG02388.1 - 8e-17 61.4 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 OAG02388.1 - 5.1e-13 48.5 6.9 9.3e-13 47.7 6.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAG02388.1 - 1.6e-07 31.5 8.8 3.2e-07 30.6 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 OAG02388.1 - 1.2e-05 25.6 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 OAG02388.1 - 0.0033 17.3 8.3 0.0059 16.5 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG02388.1 - 0.0042 16.9 8.5 0.0083 15.9 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAG02388.1 - 0.0047 16.8 3.6 0.0091 15.9 3.6 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.6 OAG02388.1 - 0.0062 16.5 5.7 0.011 15.7 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAG02388.1 - 0.019 15.2 6.9 0.05 13.9 6.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG02388.1 - 0.028 14.5 1.9 0.054 13.5 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAG02388.1 - 0.19 11.8 8.5 0.41 10.7 8.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OAG02388.1 - 1.6 8.4 8.7 1.8 8.2 6.9 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type 3HCDH_N PF02737.18 OAG02389.1 - 5.1e-30 104.7 0.0 7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG02389.1 - 5.7e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG02389.1 - 0.0037 17.4 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 OAG02389.1 - 0.0054 16.7 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 OAG02389.1 - 0.0062 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OAG02389.1 - 0.02 14.6 0.0 0.045 13.4 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAG02389.1 - 0.038 14.6 0.0 0.074 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG02389.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bestrophin PF01062.21 OAG02390.1 - 1.2e-54 185.7 0.0 2.8e-54 184.5 0.0 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PEX11 PF05648.14 OAG02391.1 - 0.0039 16.7 0.1 0.0077 15.7 0.1 1.5 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Hema_stalk PF08720.10 OAG02391.1 - 0.008 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Influenza C hemagglutinin stalk EF-hand_1 PF00036.32 OAG02392.1 - 0.00041 19.7 3.5 0.16 11.6 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OAG02392.1 - 0.0096 15.8 1.9 6.4 7.0 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OAG02392.1 - 0.9 9.1 7.1 9.7 5.9 0.1 3.4 3 0 0 3 3 3 0 EF hand Septin PF00735.18 OAG02393.1 - 4.6e-110 367.3 0.3 8.8e-110 366.4 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAG02393.1 - 2.8e-06 27.4 0.0 6.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG02393.1 - 0.0013 18.4 0.7 0.084 12.4 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG02393.1 - 0.0029 17.5 0.4 0.0029 17.5 0.4 2.7 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 OAG02393.1 - 0.0037 17.3 5.8 0.86 9.6 0.0 3.2 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.13 OAG02393.1 - 0.026 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 OAG02393.1 - 0.028 14.7 1.5 0.062 13.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 OAG02393.1 - 0.031 13.6 0.0 0.031 13.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 OAG02393.1 - 0.042 14.1 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 OAG02393.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG02393.1 - 0.36 11.3 1.8 1.5 9.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 OAG02393.1 - 1.2 8.4 4.5 0.32 10.3 0.1 2.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.32 OAG02395.1 - 0.0019 19.0 0.0 0.99 10.4 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG02395.1 - 0.0072 16.6 0.0 0.16 12.3 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 OAG02395.1 - 0.021 14.7 0.0 0.064 13.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) PQ-loop PF04193.14 OAG02396.1 - 3.7e-09 36.2 4.9 1.6e-06 27.8 0.0 3.3 2 1 1 3 3 3 2 PQ loop repeat Y_phosphatase3 PF13350.6 OAG02397.1 - 3.2e-50 171.3 0.0 3.9e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OAG02397.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Aldo_ket_red PF00248.21 OAG02398.1 - 7.2e-27 94.3 3.1 3.7e-17 62.4 0.3 2.7 1 1 1 2 2 2 2 Aldo/keto reductase family Zn_clus PF00172.18 OAG02399.1 - 4.3e-09 36.3 8.6 4.3e-09 36.3 8.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG02400.1 - 1.5e-15 56.9 2.8 5.1e-15 55.2 2.8 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG02400.1 - 0.031 13.3 0.1 0.056 12.5 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain MIT PF04212.18 OAG02400.1 - 0.1 12.7 0.0 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Transketolase_N PF00456.21 OAG02401.1 - 2.4e-129 431.1 0.0 3.2e-129 430.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG02401.1 - 3.4e-40 137.6 0.1 6e-40 136.8 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG02401.1 - 7.3e-09 35.6 0.0 2.8e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG02401.1 - 9.2e-08 31.6 0.0 2.8e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 OAG02401.1 - 0.00037 19.6 0.1 0.00084 18.4 0.1 1.6 1 0 0 1 1 1 1 Dehydrogenase E1 component PepSY_2 PF13670.6 OAG02401.1 - 0.017 15.1 0.0 0.049 13.6 0.0 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ADH_N PF08240.12 OAG02402.1 - 2.5e-29 101.4 4.5 4.5e-29 100.5 4.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG02402.1 - 2.3e-14 53.5 0.0 3.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG02402.1 - 4.5e-06 26.3 1.7 3.9e-05 23.3 1.7 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG02402.1 - 0.026 13.8 0.3 0.062 12.6 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG02402.1 - 0.028 15.5 0.0 0.081 14.0 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAG02402.1 - 0.082 12.1 0.3 1.6 7.9 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 OAG02403.1 - 2.9e-72 244.0 21.5 3.5e-72 243.7 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG02403.1 - 1.3e-18 67.1 27.6 1.7e-17 63.4 26.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG02403.1 - 0.0025 16.8 10.7 0.12 11.2 3.4 2.7 1 1 1 2 2 2 2 MFS_1 like family Zn_clus PF00172.18 OAG02404.1 - 6.2e-07 29.4 10.1 1.1e-06 28.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bax1-I PF01027.20 OAG02406.1 - 3e-53 180.7 24.1 3.5e-53 180.5 24.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.6 OAG02406.1 - 0.18 11.5 0.2 0.18 11.5 0.2 2.6 3 0 0 3 3 3 0 Sporulation protein YhaL TRAM_LAG1_CLN8 PF03798.16 OAG02407.1 - 3.6e-44 150.9 26.2 1.3e-43 149.1 20.8 2.2 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 OAG02407.1 - 4.8e-16 58.2 0.0 4.8e-16 58.2 0.0 2.8 3 0 0 3 3 3 1 TRAM1-like protein DUF1201 PF06716.11 OAG02407.1 - 6.6 6.8 12.1 1.3 9.1 1.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) adh_short PF00106.25 OAG02408.1 - 1.7e-23 83.1 2.2 2e-23 82.8 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02408.1 - 2.8e-19 69.6 0.8 3.9e-19 69.1 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG02408.1 - 6.3e-11 42.5 0.6 1.1e-10 41.7 0.6 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG02408.1 - 2.3e-05 23.7 0.1 3.6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Phytoreo_P8 PF07124.11 OAG02408.1 - 0.2 10.6 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 DUF3425 PF11905.8 OAG02409.1 - 3.3e-16 59.4 0.0 5.7e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 OAG02410.1 - 5.1e-36 124.0 1.1 7.6e-36 123.4 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02410.1 - 5.8e-30 104.6 0.4 9.2e-30 103.9 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG02410.1 - 1.6e-16 60.7 0.2 2.3e-16 60.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG02410.1 - 2.7e-10 39.9 0.1 3.2e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG02410.1 - 2.7e-09 36.9 0.8 8.1e-09 35.3 0.8 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG02410.1 - 0.015 14.7 0.2 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG02410.1 - 0.025 13.7 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 OAG02410.1 - 0.043 12.8 0.1 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family LDcluster4 PF18306.1 OAG02410.1 - 0.046 13.3 1.1 0.071 12.7 1.1 1.3 1 0 0 1 1 1 0 SLOG cluster4 family YjeF_N PF03853.15 OAG02410.1 - 0.049 13.5 0.1 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Ribonuc_L-PSP PF01042.21 OAG02411.1 - 8.3e-12 45.2 0.0 2.6e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.22 OAG02412.1 - 2.4e-31 109.0 0.1 1.3e-15 57.2 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 TetR_C_15 PF17918.1 OAG02413.1 - 0.2 12.4 1.4 13 6.6 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF3328 PF11807.8 OAG02414.1 - 7.6e-33 114.1 3.0 8.2e-33 114.0 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GMC_oxred_C PF05199.13 OAG02415.1 - 2e-30 106.2 0.1 3.1e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG02415.1 - 4.2e-30 105.1 0.0 1.1e-27 97.3 0.0 2.8 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG02415.1 - 0.00037 20.7 0.1 0.0013 18.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG02415.1 - 0.0017 17.5 0.0 0.0058 15.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG02415.1 - 0.0079 15.5 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PhoPQ_related PF10142.9 OAG02415.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Lycopene_cycl PF05834.12 OAG02415.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 OAG02415.1 - 0.17 11.5 0.2 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4889 PF16230.5 OAG02417.1 - 0.16 12.2 1.4 0.34 11.2 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) MFS_1 PF07690.16 OAG02419.1 - 1.2e-21 77.1 28.5 3.6e-21 75.5 25.2 2.5 2 1 1 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_11 PF00457.17 OAG02421.1 - 2.2e-60 203.3 17.7 2.6e-60 203.1 17.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4179 PF13786.6 OAG02421.1 - 0.026 15.0 0.2 0.067 13.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) BTB PF00651.31 OAG02423.1 - 3.3e-06 27.3 0.0 4.4e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain ADH_zinc_N PF00107.26 OAG02424.1 - 1.6e-07 31.3 0.1 2.9e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG02424.1 - 7.6e-06 25.8 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Acyl-CoA_dh_1 PF00441.24 OAG02425.1 - 2.2e-41 141.5 0.2 3.6e-41 140.9 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG02425.1 - 1.6e-31 109.3 0.1 3.9e-31 108.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG02425.1 - 2.3e-28 98.2 0.4 4.5e-28 97.3 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG02425.1 - 2.6e-15 56.9 0.0 5.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAG02425.1 - 1.3e-06 28.3 1.2 4.6e-06 26.5 1.2 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CMD PF02627.20 OAG02426.1 - 1.3e-08 34.8 1.2 2.1e-07 30.9 0.2 2.3 1 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family Lactonase PF10282.9 OAG02427.1 - 5.8e-14 52.1 0.0 1.5e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_1 PF00561.20 OAG02428.1 - 5.3e-12 45.9 0.0 2.2e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG02428.1 - 8.9e-10 39.5 0.0 2.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG02428.1 - 7.3e-06 25.4 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG02428.1 - 8.3e-06 24.7 0.0 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ndr family EthD PF07110.11 OAG02428.1 - 0.00011 23.3 0.1 0.27 12.4 0.0 2.7 2 0 0 2 2 2 2 EthD domain Esterase PF00756.20 OAG02428.1 - 0.00036 20.3 0.1 0.00094 18.9 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Cupredoxin_1 PF13473.6 OAG02430.1 - 0.033 14.3 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Cupredoxin-like domain Cu_bind_like PF02298.17 OAG02430.1 - 0.11 12.5 0.5 0.37 10.9 0.4 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.20 OAG02430.1 - 0.12 12.9 0.3 0.45 11.0 0.3 1.8 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Ribosomal_L22e PF01776.17 OAG02431.1 - 2.1e-48 163.2 1.2 2.6e-48 162.9 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Terminase_1 PF03354.15 OAG02431.1 - 0.039 12.5 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase Ofd1_CTDD PF10637.9 OAG02431.1 - 0.074 12.4 0.1 0.098 12.0 0.1 1.2 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Ribosomal_L7Ae PF01248.26 OAG02432.1 - 6.6e-20 70.7 2.6 1.3e-18 66.5 2.6 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FlaG PF03646.15 OAG02432.1 - 0.0015 18.7 7.6 0.0015 18.7 7.6 2.2 1 1 1 2 2 2 1 FlaG protein DUF4050 PF13259.6 OAG02432.1 - 0.2 12.0 4.7 0.16 12.3 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) Fungal_trans PF04082.18 OAG02433.1 - 4.6e-15 55.4 3.0 6.7e-15 54.8 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG02433.1 - 5.6e-07 29.7 15.9 0.00015 22.0 8.2 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG02433.1 - 0.0042 17.5 21.3 0.04 14.4 5.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 OAG02433.1 - 0.054 14.2 1.5 1.1 10.0 1.5 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 OAG02433.1 - 0.31 12.0 22.0 0.27 12.2 4.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 OAG02433.1 - 0.52 10.8 3.5 0.95 10.0 1.8 2.3 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 OAG02433.1 - 1.1 9.4 6.0 2.7 8.2 4.5 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 OAG02433.1 - 3.6 8.0 10.9 1.4 9.3 3.7 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RasGEF PF00617.19 OAG02435.1 - 1.2e-58 198.2 0.3 2.7e-58 197.1 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG02435.1 - 2.9e-28 98.2 0.0 7.3e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 OAG02435.1 - 1.6e-15 56.4 0.1 3.5e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG02435.1 - 3.4e-14 52.4 0.1 8.2e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG02435.1 - 2.5e-12 46.3 0.1 5.7e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 OAG02435.1 - 0.0023 18.0 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 WW domain CobT PF06213.12 OAG02435.1 - 0.17 11.3 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Glyco_hydro_16 PF00722.21 OAG02437.1 - 2.8e-21 75.8 0.5 4.8e-21 75.0 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Beta-lactamase PF00144.24 OAG02438.1 - 3e-31 108.9 0.4 4.4e-31 108.4 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase BTRD1 PF17660.1 OAG02438.1 - 3.6e-30 103.5 7.8 9.2e-11 41.4 0.1 4.5 5 0 0 5 5 5 3 Bacterial tandem repeat domain 1 LDB19 PF13002.7 OAG02441.1 - 5e-53 179.7 0.1 7.2e-53 179.2 0.1 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 OAG02441.1 - 0.00033 20.7 0.0 0.00076 19.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 OAG02441.1 - 0.00068 19.2 0.0 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 SpoOM protein DUF4606 PF15379.6 OAG02441.1 - 0.049 13.9 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) Glyco_hydro_25 PF01183.20 OAG02445.1 - 1.1e-43 149.5 0.2 1.3e-43 149.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Glyco_hydro_76 PF03663.14 OAG02446.1 - 1.1e-126 423.2 14.6 1.3e-126 423.0 14.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG02446.1 - 0.027 13.6 6.1 0.22 10.6 0.1 2.6 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 RRM_1 PF00076.22 OAG02447.1 - 1.2e-16 60.2 0.7 1.3e-15 57.0 0.0 2.8 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG02447.1 - 0.00033 20.7 0.0 0.00077 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif DLIC PF05783.11 OAG02448.1 - 7.4e-33 114.1 0.1 1.2e-31 110.1 0.0 2.8 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) Fe_bilin_red PF05996.12 OAG02448.1 - 0.082 12.6 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase NMO PF03060.15 OAG02449.1 - 2.3e-30 106.1 12.8 3.2e-24 85.9 8.1 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAG02449.1 - 1.5e-08 34.1 1.8 2.2e-08 33.5 1.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG02449.1 - 1.5e-07 30.9 0.3 2.1e-07 30.4 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG02449.1 - 2.6e-07 30.0 0.8 2.6e-06 26.7 0.7 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DUF3176 PF11374.8 OAG02450.1 - 1.3e-35 121.8 1.8 2.8e-35 120.7 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) OprF PF05736.11 OAG02451.1 - 0.071 12.8 1.5 55 3.4 0.0 3.5 1 1 3 4 4 4 0 OprF membrane domain YEATS PF03366.16 OAG02455.1 - 3.9e-27 94.0 0.1 6.5e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 YEATS family DUF3584 PF12128.8 OAG02455.1 - 0.078 10.5 7.6 0.11 10.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NAD_binding_10 PF13460.6 OAG02456.1 - 8.6e-07 29.0 0.1 2.2e-05 24.4 0.0 2.8 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG02456.1 - 5.8e-06 25.9 0.0 1.4e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG02456.1 - 1e-05 24.7 0.0 3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG02456.1 - 0.0091 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG02456.1 - 0.026 13.6 0.0 0.12 11.4 0.0 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG02456.1 - 0.036 13.2 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein NMO PF03060.15 OAG02456.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase RIO1 PF01163.22 OAG02457.1 - 1.4e-70 236.8 0.3 1.4e-70 236.8 0.3 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OAG02457.1 - 0.0019 18.2 0.1 1.2 9.1 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family APG17 PF04108.12 OAG02458.1 - 6e-115 384.5 1.0 6.9e-115 384.3 1.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Baculo_PEP_C PF04513.12 OAG02458.1 - 9.1e-06 25.8 3.8 0.44 10.6 0.1 3.5 2 1 1 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.11 OAG02458.1 - 0.0003 20.7 0.4 0.0077 16.1 0.0 2.9 3 1 0 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) EzrA PF06160.12 OAG02458.1 - 0.00091 17.5 9.1 0.088 11.0 0.1 3.0 3 0 0 3 3 3 2 Septation ring formation regulator, EzrA YabA PF06156.13 OAG02458.1 - 0.059 14.0 6.9 1.2 9.8 0.3 3.9 4 1 0 4 4 4 0 Initiation control protein YabA Phlebovirus_NSM PF07246.11 OAG02458.1 - 0.063 12.6 3.8 4.9 6.5 0.3 3.1 3 0 0 3 3 3 0 Phlebovirus nonstructural protein NS-M Taxilin PF09728.9 OAG02458.1 - 0.08 12.1 5.6 0.67 9.1 0.6 3.0 3 1 0 3 3 3 0 Myosin-like coiled-coil protein NPV_P10 PF05531.12 OAG02458.1 - 0.29 11.6 3.3 37 4.9 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PilJ PF13675.6 OAG02458.1 - 0.36 10.9 3.4 2.8 8.0 0.0 3.7 4 1 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term T3SSipB PF16535.5 OAG02458.1 - 0.72 10.3 5.0 1.9 9.0 0.3 3.0 3 1 0 3 3 3 0 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 OAG02458.1 - 1.1 9.4 11.4 0.31 11.1 0.9 4.1 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 OAG02458.1 - 1.1 8.4 2.8 4.6 6.4 0.1 2.8 3 0 0 3 3 3 0 TMPIT-like protein APG6_N PF17675.1 OAG02458.1 - 1.5 9.3 12.6 2.1 8.9 2.9 3.7 4 0 0 4 4 4 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 OAG02458.1 - 2.5 8.5 10.6 2.2 8.6 0.2 3.9 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GrpE PF01025.19 OAG02458.1 - 7.2 6.3 9.4 25 4.5 1.0 3.5 4 0 0 4 4 4 0 GrpE WD40 PF00400.32 OAG02459.1 - 2.2e-38 129.6 19.4 2.5e-06 28.1 0.0 8.8 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 OAG02459.1 - 1.7e-12 47.0 0.2 3.5e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG02459.1 - 1.4e-11 43.9 0.6 1.3e-10 40.9 0.0 2.4 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.8 OAG02459.1 - 2.7e-08 33.0 1.1 0.027 13.1 0.0 3.9 3 1 1 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAG02459.1 - 4.4e-08 33.3 0.0 0.14 12.4 0.0 5.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OAG02459.1 - 0.00028 20.9 0.0 3.1 7.9 0.0 3.4 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 OAG02459.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box Methyltransf_23 PF13489.6 OAG02461.1 - 2.6e-22 79.4 0.0 3.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02461.1 - 2.6e-09 37.7 0.0 7.4e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02461.1 - 9.3e-09 35.9 0.0 6.3e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02461.1 - 1.2e-07 32.3 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG02461.1 - 3.8e-06 26.8 0.0 9.5e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAG02461.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 OAG02461.1 - 0.23 11.0 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 OAG02462.1 - 2e-52 178.5 0.0 2.6e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.12 OAG02463.1 - 5.9e-07 29.6 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG02463.1 - 4e-06 27.2 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAG02463.1 - 0.042 14.3 0.3 0.15 12.5 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HTH_17 PF12728.7 OAG02463.1 - 0.12 12.6 0.0 13 6.0 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4936 PF16290.5 OAG02463.1 - 0.24 12.1 2.5 0.46 11.2 0.3 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4936) Ank_4 PF13637.6 OAG02465.1 - 2e-16 60.1 0.0 3.6e-08 33.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG02465.1 - 9.8e-12 45.3 0.1 1.7e-11 44.5 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG02465.1 - 2.6e-11 43.4 0.5 0.0023 18.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OAG02465.1 - 2.1e-07 30.7 0.0 0.043 14.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG02465.1 - 0.0018 18.6 0.1 0.49 10.8 0.0 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) VWA_3_C PF18571.1 OAG02465.1 - 0.029 14.2 5.2 3.4 7.6 0.3 3.1 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain DUF1843 PF08898.10 OAG02465.1 - 0.055 14.0 1.3 0.24 11.9 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 OAG02466.1 - 5.8e-19 68.5 6.3 1.6e-11 44.6 0.8 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG02466.1 - 8.2e-19 67.7 0.4 3.5e-09 37.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG02466.1 - 3.5e-14 52.5 4.6 0.0023 18.3 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OAG02466.1 - 1.9e-10 40.1 0.3 0.14 12.8 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OAG02466.1 - 0.00049 20.3 1.8 0.1 13.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 OAG02466.1 - 0.026 14.4 2.6 1.8 8.5 0.2 3.2 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Sugar_tr PF00083.24 OAG02467.1 - 7.8e-133 443.6 28.9 8.9e-133 443.4 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG02467.1 - 9.5e-25 87.3 36.6 7.1e-23 81.1 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.26 OAG02467.1 - 0.16 11.8 3.7 0.06 13.2 0.5 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel Beta-lactamase PF00144.24 OAG02469.1 - 3.2e-41 141.7 0.0 4.3e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Aminotran_5 PF00266.19 OAG02470.1 - 1.2e-59 202.1 0.0 1.8e-59 201.6 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG02470.1 - 1.1e-05 24.2 0.0 1.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG02470.1 - 0.0031 16.8 0.0 0.0096 15.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II PrpR_N PF06506.11 OAG02470.1 - 0.047 13.3 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator Flagellin_IN PF07196.13 OAG02470.1 - 0.23 11.7 1.2 8.8 6.6 0.4 2.8 1 1 1 2 2 2 0 Flagellin hook IN motif bZIP_1 PF00170.21 OAG02473.1 - 2.3e-13 50.0 8.9 2.3e-13 50.0 8.9 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAG02473.1 - 2.3e-07 30.8 8.4 2.3e-07 30.8 8.4 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG02473.1 - 0.00037 21.0 4.5 0.00037 21.0 4.5 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 OAG02473.1 - 0.13 11.6 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Fungal_trans PF04082.18 OAG02474.1 - 3.7e-15 55.7 0.2 7e-15 54.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02474.1 - 1.1e-09 38.3 10.8 2.3e-09 37.2 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DJ-1_PfpI PF01965.24 OAG02476.1 - 1.3e-07 31.6 0.1 5.5e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG02476.1 - 6.4e-06 26.0 0.0 8.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Trypsin PF00089.26 OAG02479.1 - 2.7e-62 210.5 6.5 3.1e-62 210.3 6.5 1.0 1 0 0 1 1 1 1 Trypsin Inhibitor_I66 PF16850.5 OAG02480.1 - 9.4e-07 28.8 0.0 4.1e-05 23.5 0.0 2.0 1 1 1 2 2 2 2 Peptidase inhibitor I66 Glyco_hydro_16 PF00722.21 OAG02481.1 - 5.5e-39 133.5 1.2 8.9e-39 132.8 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 OAG02482.1 - 5.8e-20 71.7 0.0 7.8e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG02482.1 - 5.9e-13 48.7 0.0 1.3e-11 44.3 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Alpha-amylase PF00128.24 OAG02483.1 - 1.5e-53 182.6 0.6 2.5e-53 181.8 0.6 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 OAG02483.1 - 5.5e-25 87.5 0.0 1.1e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) GHL15 PF14885.6 OAG02483.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 15 Catalase PF00199.19 OAG02484.1 - 2e-152 507.8 0.2 2.5e-152 507.4 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG02484.1 - 4.1e-11 42.9 0.0 7.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Preseq_ALAS PF09029.10 OAG02485.1 - 0.018 15.5 8.4 0.15 12.5 2.2 2.2 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence Dioxygenase_C PF00775.21 OAG02487.1 - 0.00055 19.4 0.0 0.00096 18.6 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Amidohydro_3 PF07969.11 OAG02488.1 - 1e-15 58.2 2.7 4.3e-11 42.9 0.2 3.6 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 OAG02488.1 - 4.4e-12 46.0 0.1 1.3e-08 34.6 0.0 3.5 3 0 0 3 3 3 3 Amidohydrolase family zf-CCHC_2 PF13696.6 OAG02490.1 - 0.00027 20.7 1.8 0.00043 20.0 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OAG02490.1 - 0.011 15.4 1.5 0.022 14.5 1.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 OAG02490.1 - 0.078 13.4 0.1 0.09 13.2 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G HET PF06985.11 OAG02491.1 - 4.4e-21 75.8 1.5 1.3e-20 74.2 0.1 2.0 1 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Catalase PF00199.19 OAG02492.1 - 8.4e-164 545.2 0.4 1.1e-163 544.8 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG02492.1 - 1.2e-08 35.1 0.1 2.1e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribosomal_L11_N PF03946.14 OAG02493.1 - 2.3e-25 88.2 0.1 4.3e-25 87.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAG02493.1 - 3.7e-15 56.2 0.6 6.4e-15 55.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Mannosyl_trans3 PF11051.8 OAG02494.1 - 0.00055 19.4 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 OAG02494.1 - 0.0066 16.0 0.4 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Glyco_hydro_20 PF00728.22 OAG02496.1 - 5.8e-97 325.2 0.4 7.3e-97 324.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAG02496.1 - 1.1e-24 87.7 0.0 2.1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAG02496.1 - 0.00021 22.1 0.4 0.00051 20.8 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 zf-CSL PF05207.13 OAG02497.1 - 0.0059 16.3 1.2 0.032 14.0 0.5 2.4 2 0 0 2 2 2 1 CSL zinc finger MFS_1 PF07690.16 OAG02498.1 - 9e-36 123.5 29.7 1.1e-35 123.2 29.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RseC_MucC PF04246.12 OAG02498.1 - 8.5 6.3 7.9 9.8 6.1 0.7 3.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC SLAC1 PF03595.17 OAG02499.1 - 3e-84 283.1 47.2 3.3e-84 282.9 47.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Aa_trans PF01490.18 OAG02500.1 - 7e-40 137.0 34.9 8.2e-40 136.7 34.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 OAG02500.1 - 3.2 7.7 5.9 1.4 8.8 0.1 3.4 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Cpn60_TCP1 PF00118.24 OAG02502.1 - 1.4e-151 505.5 5.4 1.6e-151 505.3 5.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FtsA PF14450.6 OAG02502.1 - 0.12 12.8 1.3 0.34 11.3 1.2 1.8 1 1 0 1 1 1 0 Cell division protein FtsA Rep_fac_C PF08542.11 OAG02502.1 - 0.13 12.7 0.1 20 5.7 0.0 2.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain Acyl-thio_N PF12590.8 OAG02502.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Acyl-ATP thioesterase F-box-like PF12937.7 OAG02503.1 - 1.5e-07 31.2 0.0 3.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG02503.1 - 0.00022 21.0 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 OAG02503.1 - 0.073 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 OAG02504.1 - 1.3e-60 201.4 1.3 1.4e-19 69.8 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG02504.1 - 0.063 12.4 0.2 0.26 10.4 0.0 2.0 2 0 0 2 2 2 0 Gammaproteobacterial serine protease ELYS PF13934.6 OAG02505.1 - 4.5e-58 196.8 0.1 5.4e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly RHH_4 PF13467.6 OAG02505.1 - 0.049 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain BTB PF00651.31 OAG02506.1 - 0.0075 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF4869 PF16163.5 OAG02506.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4869) CH PF00307.31 OAG02507.1 - 9.4e-08 32.2 0.0 5.4e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 OAG02507.1 - 9.1e-05 21.9 16.1 0.015 15.0 3.7 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif Peptidase_S64 PF08192.11 OAG02507.1 - 6.5 5.1 6.8 9.9 4.5 6.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Sugar_tr PF00083.24 OAG02509.1 - 8.2e-43 146.9 16.4 1.5e-42 146.1 16.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG02509.1 - 1.4e-17 63.7 21.8 1.4e-17 63.7 21.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CAAD PF14159.6 OAG02509.1 - 0.047 13.5 1.4 0.24 11.3 1.4 2.2 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase IBR PF01485.21 OAG02512.1 - 2e-11 43.9 23.3 1.9e-08 34.4 2.8 4.7 4 2 0 4 4 4 3 IBR domain, a half RING-finger domain Oxysterol_BP PF01237.18 OAG02514.1 - 2e-52 178.3 0.0 2.7e-50 171.3 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Peptidase_C2 PF00648.21 OAG02515.1 - 5.3e-27 94.6 0.0 9.7e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OAG02515.1 - 1.6e-09 38.1 0.0 1.4e-08 35.1 0.0 2.4 1 1 0 1 1 1 1 Calpain large subunit, domain III Mito_carr PF00153.27 OAG02516.1 - 1.7e-52 175.3 3.0 1.7e-20 72.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IncD PF17628.2 OAG02516.1 - 0.043 13.6 0.1 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Inclusion membrane protein D CBS PF00571.28 OAG02517.1 - 1e-20 73.9 2.8 7.6e-07 29.5 0.0 5.3 5 0 0 5 5 5 5 CBS domain DUF2434 PF10361.9 OAG02518.1 - 3.2e-111 371.0 8.3 4e-111 370.7 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF368 PF04018.13 OAG02518.1 - 0.02 14.5 1.2 0.047 13.3 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF368) Tmemb_14 PF03647.13 OAG02518.1 - 0.13 13.0 0.1 0.13 13.0 0.1 2.4 2 1 0 2 2 2 0 Transmembrane proteins 14C Phage_holin_3_7 PF05449.11 OAG02518.1 - 0.94 9.5 7.2 0.29 11.2 0.7 2.7 2 2 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 LapA_dom PF06305.11 OAG02518.1 - 2.5 8.0 4.5 21 5.0 0.1 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Peptidase_C14 PF00656.22 OAG02519.1 - 7e-62 209.6 0.0 9.2e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 OAG02519.1 - 0.15 12.0 0.4 0.81 9.6 0.0 2.3 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Sec7 PF01369.20 OAG02520.1 - 6.4e-26 91.1 0.0 1.6e-25 89.9 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 OAG02520.1 - 4.1e-18 65.9 0.0 1.1e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain MRAP PF15183.6 OAG02521.1 - 0.067 13.1 0.1 0.067 13.1 0.1 2.1 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF2207 PF09972.9 OAG02521.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3328 PF11807.8 OAG02521.1 - 0.16 11.7 0.3 14 5.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) DUF3040 PF11239.8 OAG02521.1 - 0.33 11.3 3.2 3.1 8.1 0.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) GTP_EFTU PF00009.27 OAG02522.1 - 4.5e-32 111.2 3.3 4.8e-30 104.6 3.3 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAG02522.1 - 2.3e-24 85.5 0.7 5.5e-24 84.3 0.7 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OAG02522.1 - 1.1e-08 35.1 0.1 2.6e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 OAG02522.1 - 1.8e-08 34.0 0.1 4.1e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 OAG02522.1 - 5.3e-07 29.9 2.8 0.0012 19.2 0.3 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 OAG02522.1 - 5.9e-05 22.6 0.0 0.00015 21.3 0.0 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG02522.1 - 7.4e-05 22.7 0.3 0.0012 18.7 0.0 2.4 1 1 1 2 2 2 1 RsgA GTPase MeaB PF03308.16 OAG02522.1 - 0.0014 17.7 0.5 0.0027 16.7 0.5 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 OAG02522.1 - 0.0024 17.3 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG02522.1 - 0.015 14.8 0.1 0.043 13.2 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 OAG02522.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase UNC-50 PF05216.13 OAG02523.1 - 5.3e-83 277.9 14.3 6e-83 277.8 14.3 1.0 1 0 0 1 1 1 1 UNC-50 family Suf PF05843.14 OAG02524.1 - 5.8e-88 295.7 14.1 1.2e-87 294.7 0.0 4.5 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAG02524.1 - 4.2e-05 24.0 0.2 0.026 15.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG02524.1 - 0.00098 19.6 0.0 0.9 10.1 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Guanylin PF02058.15 OAG02524.1 - 0.072 13.6 0.0 0.68 10.4 0.0 2.5 2 0 0 2 2 2 0 Guanylin precursor HAT PF02184.16 OAG02524.1 - 3.2 7.8 9.5 0.13 12.3 0.4 3.0 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat Piwi PF02171.17 OAG02525.1 - 9.7e-75 251.6 0.0 1.4e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAG02525.1 - 1.6e-20 74.1 0.0 3.9e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAG02525.1 - 3.1e-18 65.2 0.2 1e-17 63.5 0.2 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 OAG02525.1 - 1e-15 57.7 0.3 1.9e-15 56.9 0.3 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 OAG02525.1 - 6e-07 29.7 0.0 1.6e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAG02525.1 - 0.0016 18.7 0.0 0.0071 16.6 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute PP28 PF10252.9 OAG02526.1 - 6.9e-28 96.9 20.4 6.9e-28 96.9 20.4 3.2 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 PAT1 PF09770.9 OAG02526.1 - 1.8 6.7 19.1 2.2 6.4 19.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HNH PF01844.23 OAG02527.1 - 0.047 13.9 0.9 0.1 12.8 0.9 1.6 1 1 0 1 1 1 0 HNH endonuclease Med31 PF05669.12 OAG02528.1 - 0.021 14.8 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 SOH1 HET PF06985.11 OAG02530.1 - 5.1e-29 101.5 1.1 1.2e-28 100.3 1.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PipA PF07108.11 OAG02530.1 - 0.023 14.2 0.2 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 PipA protein HET PF06985.11 OAG02531.1 - 2.2e-08 34.6 1.9 4e-08 33.7 1.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mrr_cat_2 PF13156.6 OAG02532.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease Prenylcys_lyase PF07156.14 OAG02533.1 - 2.1e-93 313.4 0.0 2.5e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 OAG02533.1 - 2e-13 50.3 0.1 5.7e-13 48.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG02533.1 - 1.6e-11 44.2 0.0 1.7e-10 40.8 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG02533.1 - 3e-07 30.6 0.0 0.00068 19.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 OAG02533.1 - 7.3e-06 25.8 0.1 6e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG02533.1 - 0.0012 18.2 0.0 0.0091 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG02533.1 - 0.0094 15.2 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG02533.1 - 0.073 12.3 0.0 4 6.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 OAG02533.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 OAG02533.1 - 0.11 11.6 1.0 0.16 11.0 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAG02533.1 - 0.15 10.8 0.2 1.3 7.6 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 OAG02533.1 - 0.31 10.1 1.4 0.59 9.2 1.4 1.4 1 0 0 1 1 1 0 FAD binding domain DUF3886 PF13025.6 OAG02534.1 - 1.8 8.8 12.2 1.3 9.2 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) zf-rbx1 PF12678.7 OAG02535.1 - 7.1e-09 35.8 4.1 1.4e-08 34.9 4.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG02535.1 - 1.3e-08 35.0 3.0 1.3e-08 35.0 3.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OAG02535.1 - 2.6e-06 27.2 2.1 4.9e-06 26.3 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG02535.1 - 2.5e-05 24.1 2.3 8.4e-05 22.5 2.4 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG02535.1 - 2.5e-05 24.0 5.8 0.00018 21.3 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG02535.1 - 6.6e-05 22.9 0.8 0.00013 21.9 0.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG02535.1 - 8.9e-05 22.3 2.4 8.9e-05 22.3 2.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG02535.1 - 0.00015 21.3 0.9 0.00035 20.1 0.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OAG02535.1 - 0.0054 16.6 4.9 0.016 15.0 4.9 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OAG02535.1 - 0.013 15.3 1.2 0.041 13.6 0.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 OAG02535.1 - 0.03 14.4 3.3 0.081 13.0 3.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OAG02535.1 - 0.26 11.5 1.2 0.7 10.1 1.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAG02535.1 - 1.5 8.6 5.1 0.6 9.9 1.5 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3343 PF11823.8 OAG02536.1 - 0.026 14.0 0.9 8.5 5.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Glyco_hydro_32N PF00251.20 OAG02537.1 - 1.1e-47 163.1 1.3 1.8e-47 162.4 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAG02537.1 - 2.5e-25 89.3 0.0 4.9e-25 88.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 OAG02537.1 - 0.0024 17.2 1.0 0.029 13.7 0.1 2.1 2 0 0 2 2 2 1 BNR repeat-like domain DUF4975 PF16346.5 OAG02537.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Acetyltransf_1 PF00583.25 OAG02538.1 - 1.3e-09 38.3 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG02538.1 - 3.4e-08 33.8 0.0 5.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG02538.1 - 2.9e-06 27.2 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG02538.1 - 0.00074 19.6 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG02538.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG02538.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein PhyH PF05721.13 OAG02539.1 - 0.0032 17.7 0.0 0.015 15.6 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ECH_1 PF00378.20 OAG02541.1 - 7.5e-39 133.5 0.0 1.2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG02541.1 - 1.8e-25 90.1 0.0 2.3e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HIT PF01230.23 OAG02542.1 - 6.7e-23 81.3 0.3 9.6e-23 80.8 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAG02542.1 - 1.2e-13 51.5 0.1 1.6e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAG02542.1 - 0.00012 21.9 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.6 OAG02542.1 - 0.097 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DIM PF08194.12 OAG02543.1 - 0.076 13.2 0.4 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 DIM protein Sugar_tr PF00083.24 OAG02545.1 - 2.5e-123 412.3 29.7 2.9e-123 412.1 29.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG02545.1 - 1.9e-20 73.1 59.8 2.2e-17 63.0 32.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3731 PF12531.8 OAG02545.1 - 0.22 11.3 0.0 0.38 10.5 0.0 1.2 1 0 0 1 1 1 0 DNA-K related protein Syndecan PF01034.20 OAG02545.1 - 0.23 11.4 2.2 0.44 10.5 0.0 2.6 2 0 0 2 2 2 0 Syndecan domain TMEM132D_C PF15706.5 OAG02545.1 - 0.6 9.9 0.0 0.6 9.9 0.0 1.9 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MFS_1 PF07690.16 OAG02546.1 - 7.9e-31 107.3 24.1 7.9e-31 107.3 24.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily QRPTase_C PF01729.19 OAG02547.1 - 4.2e-54 182.8 0.3 6e-54 182.3 0.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAG02547.1 - 2.2e-05 24.4 0.0 6.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain MFS_1 PF07690.16 OAG02548.1 - 3e-43 148.1 40.1 3e-43 148.1 40.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG02548.1 - 1.3e-08 34.2 38.3 1.5e-06 27.3 38.1 3.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG02548.1 - 8.5e-07 28.6 7.5 8.5e-07 28.6 7.5 2.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Romo1 PF10247.9 OAG02548.1 - 0.16 12.4 8.9 0.085 13.2 2.3 3.1 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ADH_zinc_N_2 PF13602.6 OAG02549.1 - 4.3e-14 53.7 0.0 7.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG02549.1 - 2.2e-11 43.9 0.0 5.6e-11 42.5 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 OAG02549.1 - 0.00042 20.2 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ADH_N PF08240.12 OAG02549.1 - 0.00056 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rsd_AlgQ PF04353.13 OAG02549.1 - 0.25 11.3 0.0 0.44 10.5 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ SIR2 PF02146.17 OAG02550.1 - 1.3e-29 103.4 0.3 1.7e-21 77.0 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 OAG02550.1 - 0.0087 15.8 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Lipase_GDSL PF00657.22 OAG02551.1 - 1.3e-05 25.3 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAG02551.1 - 0.0016 18.9 0.2 0.017 15.5 0.2 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ADH_zinc_N_2 PF13602.6 OAG02552.1 - 1.2e-29 104.1 0.1 2.5e-29 103.0 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG02552.1 - 1.5e-15 57.3 0.2 2.2e-15 56.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG02552.1 - 0.0012 18.7 0.0 0.0046 16.8 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Importin_rep_4 PF18808.1 OAG02553.1 - 8.8e-36 122.1 3.4 2.3e-34 117.5 1.1 3.7 2 1 1 3 3 3 1 Importin repeat HEAT_EZ PF13513.6 OAG02553.1 - 5.8e-22 77.8 4.6 4.4e-09 36.7 0.3 8.1 6 1 2 8 8 7 4 HEAT-like repeat Importin_rep_5 PF18816.1 OAG02553.1 - 5.6e-19 68.2 0.6 2e-18 66.4 0.6 2.0 1 0 0 1 1 1 1 Importin repeat HEAT PF02985.22 OAG02553.1 - 2.6e-14 52.1 11.6 0.01 16.0 0.0 10.5 10 0 0 10 10 9 2 HEAT repeat HEAT_2 PF13646.6 OAG02553.1 - 3.9e-14 52.8 9.2 0.00041 20.7 0.0 7.2 5 2 2 7 7 6 2 HEAT repeats Importin_rep_6 PF18829.1 OAG02553.1 - 1.6e-11 44.3 0.2 1.6e-11 44.3 0.2 3.6 4 0 0 4 4 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 OAG02553.1 - 5e-09 36.6 0.0 0.17 12.5 0.0 5.8 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 OAG02553.1 - 2.7e-08 33.3 3.0 1.4e-07 31.0 1.4 3.0 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 OAG02553.1 - 9.2e-08 32.2 0.3 0.058 13.3 0.1 5.6 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 OAG02553.1 - 4e-07 30.0 0.0 0.0028 17.4 0.1 4.5 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 OAG02553.1 - 1.2e-06 28.3 0.0 0.026 14.1 0.1 4.2 4 1 0 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 OAG02553.1 - 3.2e-06 27.3 0.0 0.015 15.3 0.0 4.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAG02553.1 - 3.4e-05 22.6 0.1 0.0009 17.9 0.2 2.6 3 0 0 3 3 3 1 Adaptin N terminal region Arm PF00514.23 OAG02553.1 - 0.0041 17.1 1.3 5.8 7.1 0.0 4.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat TFCD_C PF12612.8 OAG02553.1 - 0.0051 16.7 0.0 58 3.4 0.1 5.0 5 1 0 5 5 5 0 Tubulin folding cofactor D C terminal MMS19_N PF14500.6 OAG02553.1 - 0.014 15.0 0.9 2.1 7.8 0.0 4.1 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 OAG02553.1 - 0.015 15.5 0.5 0.31 11.2 0.3 3.3 3 0 0 3 3 2 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 OAG02553.1 - 0.015 14.6 0.3 0.47 9.7 0.1 2.7 2 1 0 2 2 2 0 V-ATPase subunit H DRIM PF07539.12 OAG02553.1 - 0.015 13.6 3.8 0.11 10.8 0.7 3.4 3 2 1 4 4 4 0 Down-regulated in metastasis DUF3361 PF11841.8 OAG02553.1 - 0.13 12.2 0.1 11 5.9 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) Telomere_reg-2 PF10193.9 OAG02553.1 - 0.19 12.2 2.3 3.1 8.3 0.4 3.4 3 0 0 3 3 3 0 Telomere length regulation protein AAA PF00004.29 OAG02554.1 - 1.5e-42 145.2 0.0 2.5e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAG02554.1 - 3.9e-30 103.6 0.4 7.4e-29 99.5 0.3 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OAG02554.1 - 4e-23 81.2 4.0 4e-23 81.2 4.0 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 OAG02554.1 - 4e-06 26.7 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 OAG02554.1 - 7.5e-06 25.7 0.0 3.1e-05 23.7 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG02554.1 - 1.4e-05 25.6 0.1 0.00015 22.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAG02554.1 - 2.6e-05 24.3 0.0 0.00013 22.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAG02554.1 - 5.5e-05 23.5 0.0 0.01 16.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 OAG02554.1 - 6.9e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAG02554.1 - 0.00011 22.5 0.1 0.019 15.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 OAG02554.1 - 0.00014 21.1 0.0 0.00066 18.9 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAG02554.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 OAG02554.1 - 0.00023 20.5 0.0 0.00043 19.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 OAG02554.1 - 0.00027 21.1 0.0 0.0045 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 OAG02554.1 - 0.00063 20.3 0.2 0.0022 18.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 OAG02554.1 - 0.0017 18.5 0.0 0.0044 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAG02554.1 - 0.0021 17.8 0.0 0.0063 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG02554.1 - 0.011 16.1 0.0 0.035 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG02554.1 - 0.021 14.4 0.1 0.68 9.5 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG02554.1 - 0.022 14.3 0.1 0.11 12.0 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 OAG02554.1 - 0.027 13.9 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Phage_GPO PF05929.11 OAG02554.1 - 0.04 13.6 0.3 0.07 12.7 0.3 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase USP8_dimer PF08969.11 OAG02554.1 - 0.04 14.1 3.0 0.091 12.9 2.4 1.9 2 0 0 2 2 1 0 USP8 dimerisation domain Torsin PF06309.11 OAG02554.1 - 0.046 13.8 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin Parvo_NS1 PF01057.17 OAG02554.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 OAG02554.1 - 0.065 13.2 0.0 0.69 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 OAG02554.1 - 0.082 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 OAG02554.1 - 0.15 11.4 0.0 8.6 5.6 0.0 2.3 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 OAG02554.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 OAG02554.1 - 0.19 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Cytidylate_kin PF02224.18 OAG02554.1 - 0.21 11.3 0.9 0.51 10.0 0.0 2.1 2 1 1 3 3 3 0 Cytidylate kinase ATPase_2 PF01637.18 OAG02554.1 - 0.27 11.1 1.4 1.3 8.8 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Prefoldin_2 PF01920.20 OAG02555.1 - 4.5e-21 74.8 12.0 5.9e-21 74.4 12.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 OAG02555.1 - 8.9e-05 22.5 3.2 0.00013 22.0 3.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Spc7 PF08317.11 OAG02555.1 - 0.0049 15.8 12.5 0.0054 15.6 12.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc24 PF08286.11 OAG02555.1 - 0.0092 16.2 10.5 0.013 15.8 1.8 2.0 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 APG6_N PF17675.1 OAG02555.1 - 0.013 16.0 12.2 0.035 14.6 2.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Rh5 PF18515.1 OAG02555.1 - 0.015 14.6 4.2 0.024 14.0 4.1 1.4 1 1 0 1 1 1 0 Rh5 coiled-coil domain Prefoldin PF02996.17 OAG02555.1 - 0.016 15.1 3.5 0.016 15.1 3.5 2.3 2 1 0 2 2 2 0 Prefoldin subunit YabA PF06156.13 OAG02555.1 - 0.038 14.6 6.1 1.2 9.8 1.6 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Taxilin PF09728.9 OAG02555.1 - 0.05 12.8 10.2 0.13 11.5 1.7 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF5082 PF16888.5 OAG02555.1 - 0.064 13.5 8.6 0.074 13.3 7.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 OAG02555.1 - 0.094 13.2 10.5 1.3 9.5 1.4 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HDV_ag PF01517.18 OAG02555.1 - 0.1 12.4 1.5 0.48 10.2 0.0 2.0 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen DHR10 PF18595.1 OAG02555.1 - 0.13 12.4 13.4 0.75 9.9 2.0 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 OAG02555.1 - 0.17 11.9 11.5 0.75 9.8 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 OAG02555.1 - 0.18 11.9 7.2 0.58 10.3 0.9 2.3 2 0 0 2 2 2 0 Swi5 Occludin_ELL PF07303.13 OAG02555.1 - 0.19 12.4 4.7 0.35 11.6 1.6 2.1 1 1 1 2 2 2 0 Occludin homology domain ZapB PF06005.12 OAG02555.1 - 0.21 12.0 8.5 0.23 11.9 1.7 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 OAG02555.1 - 0.27 10.5 10.0 0.3 10.4 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OAG02555.1 - 0.34 10.7 16.0 0.64 9.8 3.2 3.1 2 1 1 3 3 3 0 Septum formation initiator CENP-H PF05837.12 OAG02555.1 - 0.4 11.1 8.6 0.55 10.7 0.8 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ABC_tran_CTD PF16326.5 OAG02555.1 - 0.45 10.8 10.2 3.5 7.9 0.3 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 OAG02555.1 - 0.5 10.8 7.0 1.9 8.9 1.0 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PHM7_cyt PF14703.6 OAG02555.1 - 0.57 10.4 6.0 1.1 9.5 6.0 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MIP-T3_C PF17749.1 OAG02555.1 - 0.58 10.1 13.4 0.044 13.8 5.2 2.3 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region COG2 PF06148.11 OAG02555.1 - 0.61 10.2 7.8 4.2 7.5 1.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4349 PF14257.6 OAG02555.1 - 0.61 9.5 9.6 0.15 11.5 3.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) Tropomyosin_1 PF12718.7 OAG02555.1 - 0.69 10.1 12.2 3.2 7.9 2.3 2.1 2 0 0 2 2 2 0 Tropomyosin like LPP PF04728.13 OAG02555.1 - 0.93 9.9 15.8 0.29 11.5 6.7 2.9 2 2 0 2 2 2 0 Lipoprotein leucine-zipper YgaB PF14182.6 OAG02555.1 - 1 9.8 10.1 4 7.9 3.3 2.3 1 1 1 2 2 2 0 YgaB-like protein Muted PF14942.6 OAG02555.1 - 1.5 9.2 11.2 3.5 7.9 2.8 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein ADIP PF11559.8 OAG02555.1 - 3 7.9 12.6 5.2 7.1 3.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 OAG02555.1 - 5.1 6.9 11.3 49 3.7 11.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 OAG02555.1 - 7.9 6.7 11.0 80 3.4 11.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_M66 PF10462.9 OAG02556.1 - 0.26 10.2 1.2 0.4 9.6 1.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M6 PF05547.11 OAG02556.1 - 0.26 9.5 0.9 0.53 8.6 0.9 1.5 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 PIP5K PF01504.18 OAG02557.1 - 3.1e-102 341.5 0.5 3.1e-102 341.5 0.5 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.19 OAG02558.1 - 2.1e-24 85.7 0.3 6.9e-24 84.0 0.3 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF3591 PF12157.8 OAG02559.1 - 5.3e-168 559.2 1.5 8.3e-168 558.6 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 OAG02559.1 - 0.005 16.9 0.7 0.0083 16.2 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 OAG02559.1 - 0.019 14.8 1.7 0.048 13.5 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_15 PF09445.10 OAG02560.1 - 2.6e-51 173.5 0.1 3.2e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OAG02560.1 - 1.9e-09 37.5 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 OAG02560.1 - 8.4e-06 25.6 0.0 2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 OAG02560.1 - 6.8e-05 22.6 0.0 9.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 OAG02560.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_18 PF12847.7 OAG02560.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DNA_methylase PF00145.17 OAG02560.1 - 0.0029 17.0 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase PrmA PF06325.13 OAG02560.1 - 0.006 16.0 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAG02560.1 - 0.0084 16.8 0.0 0.016 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 OAG02560.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_3 PF01596.17 OAG02560.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_5 PF01795.19 OAG02560.1 - 0.054 13.0 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family MTS PF05175.14 OAG02560.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GRASP55_65 PF04495.14 OAG02561.1 - 2.5e-49 167.1 0.0 1e-45 155.4 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 OAG02561.1 - 2.3e-05 24.2 0.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OAG02561.1 - 0.14 12.5 0.0 10 6.5 0.0 2.4 2 0 0 2 2 2 0 PDZ domain DUF2367 PF10164.9 OAG02564.1 - 0.052 14.0 2.0 0.15 12.6 2.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) C1_2 PF03107.16 OAG02564.1 - 8.7 6.7 12.3 4 7.8 9.2 2.1 2 0 0 2 2 2 0 C1 domain Lactamase_B_3 PF13483.6 OAG02565.1 - 4.4e-08 33.2 0.0 1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAG02565.1 - 0.00031 20.3 0.0 0.00048 19.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2855 PF11017.8 OAG02567.1 - 7.5e-74 249.5 0.0 8.5e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) GYF_2 PF14237.6 OAG02567.1 - 0.009 15.8 2.1 0.019 14.8 2.1 1.5 1 0 0 1 1 1 1 GYF domain 2 Aa_trans PF01490.18 OAG02568.1 - 9.2e-34 116.8 37.8 1.1e-33 116.5 37.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAG02568.1 - 0.0015 17.7 19.8 0.0015 17.7 19.8 2.0 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family CBS PF00571.28 OAG02569.1 - 1.7e-34 118.1 5.0 1.6e-09 38.0 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 OAG02569.1 - 4.7e-10 39.3 0.2 1.6e-09 37.5 0.0 2.1 2 1 0 2 2 2 1 PB1 domain PNRC PF15365.6 OAG02569.1 - 9 6.2 11.9 0.82 9.6 1.9 3.0 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator motif Ribosomal_S26e PF01283.19 OAG02570.1 - 8.9e-52 174.1 8.0 1.1e-51 173.8 8.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 OAG02570.1 - 0.021 14.8 0.5 0.061 13.3 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 OAG02570.1 - 0.085 12.7 0.4 0.13 12.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) DUF1918 PF08940.11 OAG02570.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) VanZ PF04892.12 OAG02571.1 - 4.2e-07 30.7 1.4 5.9e-07 30.2 1.4 1.2 1 0 0 1 1 1 1 VanZ like family Bromodomain PF00439.25 OAG02572.1 - 9.1e-19 67.3 0.5 2.4e-18 66.0 0.5 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 OAG02572.1 - 2.7e-06 27.3 0.0 6.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated SPARC_Ca_bdg PF10591.9 OAG02572.1 - 0.03 14.6 1.6 0.093 13.1 0.4 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Gti1_Pac2 PF09729.9 OAG02573.1 - 0.029 14.5 0.1 0.038 14.1 0.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Rhomboid PF01694.22 OAG02575.1 - 1.1e-21 77.4 12.1 3.4e-21 75.8 10.3 2.0 2 0 0 2 2 2 1 Rhomboid family DEAD PF00270.29 OAG02576.1 - 1.4e-41 142.1 0.0 2.1e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG02576.1 - 1.7e-28 99.2 0.5 6e-27 94.2 0.5 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG02576.1 - 0.0049 16.9 0.0 0.0096 15.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG02576.1 - 0.049 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Thioredoxin PF00085.20 OAG02577.1 - 7e-65 215.5 4.1 9.7e-31 105.8 0.1 4.4 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 OAG02577.1 - 4.1e-51 173.5 0.7 9.5e-36 123.4 0.1 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 OAG02577.1 - 3.1e-11 43.0 0.6 6.5e-11 41.9 0.6 1.5 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 OAG02577.1 - 3.4e-09 37.1 1.1 0.0015 19.0 0.1 4.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAG02577.1 - 2e-08 34.4 0.1 0.14 12.5 0.0 4.7 4 1 1 5 5 5 3 Thioredoxin-like Thioredoxin_7 PF13899.6 OAG02577.1 - 1.8e-07 31.2 0.0 0.037 14.2 0.0 3.2 3 0 0 3 3 2 2 Thioredoxin-like OST3_OST6 PF04756.13 OAG02577.1 - 2.2e-07 30.5 0.2 0.045 13.1 0.0 3.2 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAG02577.1 - 2.2e-05 24.4 0.5 0.064 13.2 0.1 3.0 2 1 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 OAG02577.1 - 0.0018 18.0 1.8 0.58 9.9 0.0 3.5 3 1 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 OAG02577.1 - 0.0059 16.6 0.1 0.034 14.2 0.1 2.3 1 0 0 1 1 1 1 Thioredoxin domain REF PF05755.12 OAG02577.1 - 0.2 11.4 8.9 0.71 9.6 8.9 1.9 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) ISG65-75 PF11727.8 OAG02577.1 - 0.39 9.9 14.3 0.67 9.1 14.3 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Apolipoprotein PF01442.18 OAG02577.1 - 0.61 9.9 12.0 0.24 11.3 8.7 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain EspB PF05802.11 OAG02577.1 - 1.6 8.6 14.1 3.7 7.5 14.1 1.6 1 0 0 1 1 1 0 Enterobacterial EspB protein YtxH PF12732.7 OAG02577.1 - 1.7 9.3 18.9 0.44 11.1 8.9 3.6 3 1 1 4 4 4 0 YtxH-like protein ApoLp-III PF07464.11 OAG02577.1 - 1.9 8.6 10.5 1.5 8.9 8.1 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 OAG02577.1 - 3.1 8.4 11.1 4.6 7.9 4.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) GFA PF04828.14 OAG02580.1 - 3.8e-22 78.4 1.2 5.4e-22 77.9 1.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 OAG02580.1 - 0.0074 16.8 2.9 0.042 14.4 0.1 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Nudix_N_2 PF14803.6 OAG02580.1 - 0.17 11.8 3.9 5.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 OAG02580.1 - 0.4 10.5 6.1 4 7.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 OAG02580.1 - 0.44 10.7 0.1 0.44 10.7 0.1 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 OAG02580.1 - 1.8 8.1 8.1 10 5.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 OAG02580.1 - 3.4 7.4 12.5 0.67 9.7 1.3 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain GST_N_3 PF13417.6 OAG02581.1 - 1.1e-19 70.6 0.1 1.9e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG02581.1 - 5.8e-19 68.2 0.3 2e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG02581.1 - 4.5e-11 42.9 0.3 8.5e-11 42.1 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG02581.1 - 2.4e-05 24.3 0.1 5.5e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG02581.1 - 8.9e-05 23.2 0.0 0.00017 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 OAG02581.1 - 0.00081 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG02582.1 - 2.5e-25 90.1 0.1 5e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG02582.1 - 6.2e-19 68.3 0.9 1.9e-18 66.7 0.5 1.8 1 1 0 2 2 2 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.16 OAG02582.1 - 0.14 12.8 0.0 31 5.3 0.0 2.7 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II adh_short PF00106.25 OAG02582.1 - 0.9 9.0 2.7 0.89 9.0 0.5 2.0 2 1 0 3 3 3 0 short chain dehydrogenase Ytp1 PF10355.9 OAG02584.1 - 5.3e-118 393.2 10.0 8.9e-118 392.5 10.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAG02584.1 - 4e-27 94.1 7.3 4e-27 94.1 7.3 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DASH_Dam1 PF08653.10 OAG02585.1 - 1.6e-27 95.1 1.5 2.2e-27 94.6 1.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 THRAP3_BCLAF1 PF15440.6 OAG02585.1 - 2.3 7.1 11.3 3 6.7 11.3 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family CRAL_TRIO PF00650.20 OAG02586.1 - 3.8e-44 150.2 0.0 5.9e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG02586.1 - 1e-13 51.2 0.2 2.7e-13 49.9 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG02586.1 - 1.7e-07 31.5 0.0 4.6e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Ribosomal_S2 PF00318.20 OAG02587.1 - 2.9e-66 222.8 0.2 3.2e-65 219.4 0.2 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 PAS_9 PF13426.7 OAG02588.1 - 1.7e-23 82.8 0.0 7.1e-15 55.1 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 OAG02588.1 - 1.8e-18 66.6 0.0 1.8e-10 41.0 0.0 3.9 4 0 0 4 4 4 3 PAS fold GATA PF00320.27 OAG02588.1 - 4.2e-15 55.0 8.9 8.8e-15 54.0 8.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 OAG02588.1 - 3.5e-13 49.5 0.0 7.2e-05 22.8 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 OAG02588.1 - 1.5e-08 34.7 0.0 0.00088 19.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OAG02588.1 - 6.7e-06 26.3 0.0 0.37 11.0 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 OAG02588.1 - 0.0012 19.5 0.0 0.17 12.6 0.0 3.4 3 0 0 3 3 3 1 PAS fold Glyco_hydro_61 PF03443.14 OAG02590.1 - 5.4e-61 206.1 0.0 6.8e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MAM33 PF02330.16 OAG02592.1 - 5.2e-75 252.0 2.4 1.4e-74 250.7 2.4 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein MukF_C PF17193.4 OAG02592.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 MukF C-terminal domain Mito_carr PF00153.27 OAG02593.1 - 8.1e-52 173.1 4.7 7.1e-21 73.9 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Fungal_trans PF04082.18 OAG02594.1 - 3.8e-15 55.6 0.0 6.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02594.1 - 1.3e-09 38.0 8.8 2.2e-09 37.3 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TLD PF07534.16 OAG02595.1 - 1.2e-25 90.4 0.0 5.3e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 TLD Hydantoinase_B PF02538.14 OAG02596.1 - 2.8e-186 619.9 0.1 3.7e-186 619.5 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAG02596.1 - 2.3e-89 299.5 0.1 4.5e-89 298.6 0.1 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG02596.1 - 2.1e-52 177.4 0.1 3.4e-50 170.2 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.18 OAG02597.1 - 9.5e-19 67.5 0.2 1.7e-18 66.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RasGEF_N_2 PF14663.6 OAG02597.1 - 0.019 15.3 0.5 0.06 13.8 0.1 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Abhydrolase_1 PF00561.20 OAG02598.1 - 2.8e-26 92.7 0.3 4.2e-26 92.1 0.3 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG02598.1 - 2.3e-21 76.2 0.1 3.7e-21 75.5 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG02598.1 - 2.8e-19 70.6 0.0 4e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG02598.1 - 6.2e-09 35.6 0.1 3.9e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 OAG02598.1 - 9e-05 21.3 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 OAG02598.1 - 0.0094 15.7 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 OAG02598.1 - 0.026 13.3 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF2920 PF11144.8 OAG02598.1 - 0.042 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 OAG02598.1 - 0.044 13.6 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 OAG02598.1 - 0.05 13.3 0.1 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) MFS_1 PF07690.16 OAG02599.1 - 2.1e-35 122.3 22.5 2.1e-35 122.3 22.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 OAG02599.1 - 0.0049 15.7 3.3 0.0049 15.7 3.3 2.2 2 1 0 2 2 2 1 LacY proton/sugar symporter TMEM189_B_dmain PF10520.9 OAG02601.1 - 0.03 14.4 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain Zn_clus PF00172.18 OAG02603.1 - 6.4e-09 35.8 13.4 1.1e-08 35.1 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4175 PF13779.6 OAG02603.1 - 0.032 12.2 0.1 0.036 12.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NUDE_C PF04880.13 OAG02603.1 - 2.6 8.5 7.4 0.35 11.3 3.4 1.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Aldose_epim PF01263.20 OAG02604.1 - 7.9e-65 219.1 0.1 9.6e-65 218.8 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Mrx7 PF10906.8 OAG02609.1 - 2.1e-10 40.7 0.0 6e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 MIOREX complex component 7 DUF2852 PF11014.8 OAG02609.1 - 0.096 12.9 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Y_phosphatase PF00102.27 OAG02611.1 - 3.8e-59 200.1 0.0 5.3e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OAG02611.1 - 0.0044 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Mon1 PF03164.14 OAG02612.1 - 2.1e-150 501.3 0.0 2.5e-150 501.1 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Pkinase_fungal PF17667.1 OAG02612.1 - 0.051 12.4 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SPX PF03105.19 OAG02612.1 - 9.4 6.0 9.8 15 5.4 9.8 1.2 1 0 0 1 1 1 0 SPX domain BSP_II PF05432.11 OAG02614.1 - 0.0093 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Arfaptin PF06456.13 OAG02614.1 - 0.017 14.7 0.5 4.4 6.8 0.5 2.6 2 1 0 2 2 2 0 Arfaptin-like domain D-ser_dehydrat PF14031.6 OAG02616.1 - 2.6e-21 76.1 0.0 6.2e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 OAG02616.1 - 6.5e-14 52.1 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ion_trans PF00520.31 OAG02618.1 - 0.00044 19.5 12.5 0.001 18.3 12.5 1.6 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OAG02618.1 - 0.0015 17.3 4.5 0.092 11.4 0.3 2.3 2 0 0 2 2 2 2 Polycystin cation channel HlyIII PF03006.20 OAG02618.1 - 1.8 8.2 10.7 6.3 6.4 10.7 1.8 1 1 0 1 1 1 0 Haemolysin-III related Fungal_trans_2 PF11951.8 OAG02619.1 - 1.2e-07 30.9 4.1 1.4e-07 30.6 4.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gln-synt_C PF00120.24 OAG02620.1 - 4.2e-54 183.9 0.0 1.4e-53 182.1 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 OAG02620.1 - 2.5e-13 50.5 0.0 4.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase DUF3328 PF11807.8 OAG02621.1 - 8.3e-20 71.5 5.1 3.1e-19 69.6 5.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_72 PF03198.14 OAG02623.1 - 2e-133 444.5 7.8 2.6e-133 444.2 7.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 OAG02623.1 - 3.4e-23 82.1 4.3 9.3e-23 80.7 4.3 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_114 PF03537.13 OAG02623.1 - 0.085 12.2 1.4 0.76 9.0 0.1 2.2 1 1 1 2 2 2 0 Glycoside-hydrolase family GH114 Glucan_synthase PF02364.15 OAG02625.1 - 0 1382.9 0.0 0 1382.3 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OAG02625.1 - 1.3e-42 145.1 0.8 4.3e-42 143.5 0.8 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MerT PF02411.15 OAG02625.1 - 0.44 10.6 6.7 0.2 11.7 2.9 2.5 2 0 0 2 2 2 0 MerT mercuric transport protein Aminotran_1_2 PF00155.21 OAG02626.1 - 7.7e-37 127.3 0.0 1e-36 126.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG02626.1 - 3.4e-05 22.6 0.0 5.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Bacteriocin_IIc PF10439.9 OAG02627.1 - 6.7 6.9 6.8 1.2 9.4 0.4 2.6 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide DUF2839 PF10999.8 OAG02627.1 - 7.2 7.1 12.8 7.6 7.0 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) BPD_transp_2 PF02653.16 OAG02627.1 - 9.2 5.3 24.2 20 4.2 19.9 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component Whi5 PF08528.11 OAG02628.1 - 6.2e-10 38.5 0.3 1.4e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 Whi5 like DNAPolymera_Pol PF11590.8 OAG02628.1 - 0.098 12.6 2.8 3.8 7.5 0.6 2.4 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol Metallopep PF12044.8 OAG02629.1 - 1.8e-169 563.9 0.0 2.2e-169 563.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.6 OAG02629.1 - 0.046 13.6 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAG02629.1 - 0.046 13.9 0.3 0.1 12.7 0.3 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Jacalin PF01419.17 OAG02629.1 - 0.21 11.5 0.1 7.6 6.5 0.0 2.7 2 1 1 3 3 3 0 Jacalin-like lectin domain CDP-OH_P_transf PF01066.21 OAG02630.1 - 4.1e-12 46.7 0.9 1e-11 45.4 0.1 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.14 OAG02631.1 - 7.7e-36 123.2 0.0 1e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 OAG02632.1 - 5.3e-32 111.2 0.0 7.1e-30 104.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG02632.1 - 4.4e-19 68.4 0.6 9.7e-19 67.3 0.6 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OAG02632.1 - 4.4e-14 52.3 0.2 1.1e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 OAG02632.1 - 2.8e-08 33.7 0.0 5.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain SAM_2 PF07647.17 OAG02633.1 - 1.2e-08 35.0 0.2 2.1e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAG02633.1 - 1.7e-05 25.2 0.2 4.7e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HemN_C PF06969.16 OAG02633.1 - 0.015 15.4 0.6 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 HemN C-terminal domain DUF4508 PF14969.6 OAG02633.1 - 0.12 12.7 0.4 0.28 11.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) FRB_dom PF08771.11 OAG02633.1 - 0.13 12.7 0.2 0.36 11.3 0.2 1.7 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain IGR PF09597.10 OAG02633.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif COG5 PF10392.9 OAG02634.1 - 1e-39 135.7 1.6 3.6e-39 134.0 0.1 2.3 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Ureidogly_lyase PF04115.12 OAG02635.1 - 6.1e-70 234.8 0.0 7.5e-70 234.5 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase Glyco_hydro_16 PF00722.21 OAG02636.1 - 2.8e-05 23.7 0.3 0.00017 21.1 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Ribonuclease_T2 PF00445.18 OAG02637.1 - 7.4e-43 146.9 0.8 7.4e-43 146.9 0.8 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family SBDS_C PF09377.10 OAG02637.1 - 0.093 12.7 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 SBDS protein C-terminal domain Acetyltransf_1 PF00583.25 OAG02638.1 - 1.4e-07 31.7 0.0 2.2e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG02638.1 - 7.6e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG02638.1 - 2.3e-05 24.7 0.0 4.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG02638.1 - 0.0024 18.0 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG02638.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 OAG02638.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NDUF_C2 PF06374.11 OAG02638.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) EHN PF06441.12 OAG02639.1 - 3.2e-37 127.2 0.0 3.2e-37 127.2 0.0 1.9 2 1 0 2 2 2 1 Epoxide hydrolase N terminus HAD_SAK_1 PF10307.9 OAG02640.1 - 7.6e-78 261.0 0.1 1.1e-77 260.5 0.1 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins zf-RING_2 PF13639.6 OAG02641.1 - 2.9e-09 37.1 9.2 6.1e-09 36.1 9.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAG02641.1 - 5.8e-07 29.3 6.1 9.2e-07 28.6 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG02641.1 - 3.1e-06 27.4 5.2 7.8e-06 26.1 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG02641.1 - 1.6e-05 24.6 8.6 2.8e-05 23.8 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG02641.1 - 0.00018 21.3 8.0 0.00031 20.5 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG02641.1 - 0.0069 16.2 7.7 0.013 15.4 7.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OAG02641.1 - 0.53 10.1 6.0 1.2 9.0 6.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 OAG02641.1 - 0.84 9.7 6.4 1.5 8.9 4.9 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Epimerase PF01370.21 OAG02642.1 - 2.4e-15 56.7 0.0 4.4e-15 55.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG02642.1 - 4.6e-09 36.1 0.0 8.9e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG02642.1 - 3.2e-06 26.4 0.0 5.3e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG02642.1 - 8.9e-06 25.0 0.0 2.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 OAG02642.1 - 0.032 13.8 0.0 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family KR PF08659.10 OAG02642.1 - 0.037 13.9 0.2 0.42 10.5 0.2 2.1 1 1 0 1 1 1 0 KR domain zf-C2H2_4 PF13894.6 OAG02643.1 - 0.00051 20.6 4.8 0.0013 19.4 4.8 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG02643.1 - 0.00056 20.2 5.9 0.0013 19.1 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 OAG02643.1 - 0.0046 16.7 3.4 0.01 15.6 3.4 1.5 1 0 0 1 1 1 1 zinc-finger C2H2-type Mfa_like_2 PF15415.6 OAG02643.1 - 0.01 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Fimbrillin-like zf-BED PF02892.15 OAG02643.1 - 0.047 13.7 1.9 0.081 13.0 1.9 1.4 1 0 0 1 1 1 0 BED zinc finger Cupin_2 PF07883.11 OAG02644.1 - 5.6e-15 54.8 0.4 8.6e-15 54.2 0.4 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG02644.1 - 5.1e-08 32.9 0.1 7.4e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAG02644.1 - 7.1e-06 25.7 0.0 9.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG02644.1 - 0.00032 20.3 0.1 0.00056 19.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Auxin_BP PF02041.16 OAG02644.1 - 0.014 15.1 0.1 0.057 13.1 0.1 1.9 1 1 0 1 1 1 0 Auxin binding protein Cupin_6 PF12852.7 OAG02644.1 - 0.019 14.7 0.1 0.03 14.1 0.1 1.4 1 1 0 1 1 1 0 Cupin MannoseP_isomer PF01050.18 OAG02644.1 - 0.024 14.5 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DMSP_lyase PF16867.5 OAG02644.1 - 0.027 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase ARD PF03079.14 OAG02644.1 - 0.04 14.1 0.3 0.057 13.6 0.3 1.2 1 0 0 1 1 1 0 ARD/ARD' family CENP-C_C PF11699.8 OAG02644.1 - 0.065 13.4 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like F-box PF00646.33 OAG02645.1 - 0.00016 21.4 0.7 0.00062 19.6 0.2 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG02645.1 - 0.0019 18.0 0.8 0.0043 16.9 0.8 1.6 1 0 0 1 1 1 1 F-box-like Folliculin PF11704.8 OAG02646.1 - 3.3e-52 177.1 0.0 5.4e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport MT0933_antitox PF14013.6 OAG02647.1 - 0.091 13.1 3.1 1.1 9.6 0.6 2.1 1 1 1 2 2 2 0 MT0933-like antitoxin protein CorA PF01544.18 OAG02648.1 - 2.3e-13 50.1 0.4 3e-13 49.7 0.4 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FixP_N PF14715.6 OAG02648.1 - 0.026 14.3 0.9 0.059 13.1 0.9 1.5 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF2207 PF09972.9 OAG02648.1 - 0.071 11.9 0.1 0.08 11.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Nop14 PF04147.12 OAG02649.1 - 0.086 11.0 11.5 0.12 10.6 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAG02649.1 - 0.17 9.9 21.1 0.26 9.4 21.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 OAG02649.1 - 0.25 10.7 12.7 0.38 10.1 12.7 1.2 1 0 0 1 1 1 0 SDA1 TFB6 PF17110.5 OAG02649.1 - 0.41 10.4 5.9 0.77 9.5 5.9 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 OAG02649.1 - 1.1 7.4 8.9 1.6 6.9 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 OAG02649.1 - 2 8.4 7.4 4 7.4 7.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal MPP6 PF10175.9 OAG02649.1 - 2.8 8.4 7.2 6 7.4 7.2 1.5 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Paf1 PF03985.13 OAG02649.1 - 3.6 6.5 12.1 6.4 5.7 12.1 1.3 1 0 0 1 1 1 0 Paf1 Radial_spoke PF04712.12 OAG02649.1 - 4.2 6.2 9.6 6.1 5.7 9.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein BUD22 PF09073.10 OAG02649.1 - 4.6 6.5 11.2 7 5.9 11.2 1.2 1 0 0 1 1 1 0 BUD22 RINT1_TIP1 PF04437.13 OAG02650.1 - 6.4e-172 572.9 0.0 3.9e-171 570.3 0.0 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Fez1 PF06818.15 OAG02650.1 - 0.25 11.8 4.7 0.43 11.0 4.7 1.3 1 0 0 1 1 1 0 Fez1 CRISPR_Cse2 PF09485.10 OAG02650.1 - 0.37 11.3 10.3 0.24 11.9 6.8 2.4 2 1 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Med2 PF11214.8 OAG02650.1 - 1.1 9.5 3.2 14 5.9 0.4 3.0 3 1 0 3 3 3 0 Mediator complex subunit 2 PUF PF00806.19 OAG02651.1 - 9.7e-13 47.0 0.0 2.3 8.1 0.0 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat Bcl-2 PF00452.19 OAG02651.1 - 0.062 14.0 0.0 0.29 11.9 0.0 2.1 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family Pyridoxal_deC PF00282.19 OAG02652.1 - 1.4e-68 231.3 0.0 1.9e-65 221.0 0.0 2.5 2 1 1 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAG02652.1 - 1.8e-06 27.5 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAG02652.1 - 0.00018 20.6 0.0 0.00045 19.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V AAA PF00004.29 OAG02654.1 - 5.1e-18 65.8 0.0 1.6e-17 64.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG02654.1 - 0.00024 21.4 0.1 0.0017 18.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG02654.1 - 0.00059 20.3 0.0 0.0013 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG02654.1 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OAG02654.1 - 0.0071 16.2 0.1 0.05 13.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 OAG02654.1 - 0.024 14.8 0.0 0.074 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zot PF05707.12 OAG02654.1 - 0.026 14.2 0.1 0.83 9.3 0.0 2.3 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 OAG02654.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG02654.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG02654.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAG02654.1 - 0.18 11.1 1.5 0.78 9.0 0.1 2.7 4 0 0 4 4 4 0 KaiC LETM1 PF07766.13 OAG02655.1 - 5.6e-14 52.1 0.1 1e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 LETM1-like protein CLP1_P PF16575.5 OAG02656.1 - 3.6e-16 59.5 0.0 5.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF3159 PF11361.8 OAG02656.1 - 0.93 9.2 3.3 2 8.1 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) DUF5538 PF17692.1 OAG02657.1 - 0.026 14.6 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5538) RRM_1 PF00076.22 OAG02658.1 - 1.6e-08 34.3 0.0 3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAG02658.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 OAG02658.1 - 0.024 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 OAG02659.1 - 1.7e-19 69.9 1.6 2.4e-19 69.4 1.6 1.2 1 0 0 1 1 1 1 RF-1 domain U3_assoc_6 PF08640.11 OAG02660.1 - 1.8e-24 85.6 1.5 1.8e-24 85.6 1.5 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 OAG02660.1 - 7.4e-08 32.6 2.8 0.016 15.9 0.0 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat NRDE-2 PF08424.10 OAG02660.1 - 0.00041 19.6 0.0 0.0011 18.1 0.0 1.7 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 OAG02660.1 - 0.16 12.5 1.2 14 6.3 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Frag1 PF10277.9 OAG02661.1 - 3e-36 125.0 11.0 3e-36 125.0 11.0 2.5 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 OAG02661.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FHA PF00498.26 OAG02662.1 - 7.9e-14 51.8 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG02662.1 - 0.0044 17.3 0.1 2.4 8.5 0.0 2.3 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain DUF4542 PF15075.6 OAG02663.1 - 0.54 10.6 2.4 0.7 10.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) TMF_TATA_bd PF12325.8 OAG02663.1 - 3.4 7.9 41.6 0.082 13.1 12.6 4.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 OAG02663.1 - 8.5 5.1 41.5 1.5 7.6 12.7 3.4 3 0 0 3 3 3 0 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.9 OAG02663.1 - 8.9 6.7 11.3 4 7.8 0.3 3.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Cnn_1N PF07989.11 OAG02664.1 - 9.1e-22 77.0 14.8 9.1e-22 77.0 14.8 13.1 9 2 2 12 12 12 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 OAG02664.1 - 1e-18 67.4 16.5 1e-18 67.4 16.5 12.6 10 3 4 14 14 14 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Uso1_p115_C PF04871.13 OAG02665.1 - 0.015 15.6 3.2 0.015 15.6 3.2 2.8 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ubiquitin_2 PF14560.6 OAG02665.1 - 0.074 13.5 0.2 4.3 7.9 0.0 3.1 3 1 0 3 3 3 0 Ubiquitin-like domain Fungal_TACC PF12709.7 OAG02665.1 - 1.5 9.3 9.3 3.5 8.2 0.2 3.8 2 2 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_1 PF00170.21 OAG02665.1 - 3.8 7.7 8.0 5.8 7.1 0.6 3.0 3 0 0 3 3 3 0 bZIP transcription factor MARVEL PF01284.23 OAG02666.1 - 0.0011 19.0 5.5 0.002 18.2 5.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 OAG02666.1 - 0.0042 17.5 0.4 0.04 14.4 0.4 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4231) DUF588 PF04535.12 OAG02666.1 - 0.13 12.0 1.1 0.44 10.3 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF588) GTP_EFTU PF00009.27 OAG02667.1 - 3.6e-07 29.9 0.0 1.2e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain OMPdecase PF00215.24 OAG02667.1 - 0.095 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family AP4E_app_platf PF14807.6 OAG02668.1 - 0.091 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform zf-C2H2 PF00096.26 OAG02669.1 - 0.0084 16.5 4.1 0.42 11.1 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG02669.1 - 0.016 16.0 2.8 4 8.5 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Cys_Met_Meta_PP PF01053.20 OAG02672.1 - 4.8e-37 127.4 0.0 7.1e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG02672.1 - 0.095 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Nrap_D4 PF17405.2 OAG02673.1 - 4.1e-59 199.5 0.4 8.1e-59 198.6 0.4 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 OAG02673.1 - 6.1e-58 195.2 0.1 4.9e-57 192.2 0.1 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 OAG02673.1 - 1.4e-51 174.5 0.3 4.2e-51 173.0 0.1 2.0 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D2 PF17403.2 OAG02673.1 - 4.3e-50 169.4 0.0 7e-49 165.5 0.0 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 OAG02673.1 - 5.2e-44 150.1 0.7 2.2e-43 148.1 0.0 2.2 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 OAG02673.1 - 1.2e-28 100.0 0.0 2.9e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Transp_cyt_pur PF02133.15 OAG02674.1 - 1.8e-18 66.6 34.1 1.8e-18 66.6 34.1 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1294 PF06961.13 OAG02674.1 - 2.3 8.5 4.1 2.3 8.5 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1294) Peptidase_M48_N PF16491.5 OAG02674.1 - 3.1 7.7 12.0 0.26 11.2 6.3 2.2 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices p450 PF00067.22 OAG02676.1 - 1.5e-65 221.8 0.0 1.9e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Calreticulin PF00262.18 OAG02676.1 - 0.091 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Calreticulin family Fungal_trans PF04082.18 OAG02677.1 - 2.2e-12 46.6 0.1 3.9e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG02677.1 - 7.1e-05 23.1 15.7 0.0035 17.7 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG02677.1 - 0.00019 21.7 4.8 0.00019 21.7 4.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG02677.1 - 0.0099 16.6 14.0 0.29 12.1 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG02677.1 - 0.37 11.1 5.1 5.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 OAG02677.1 - 2.3 8.2 4.3 4 7.4 0.3 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PCMT PF01135.19 OAG02678.1 - 7.1e-73 244.8 0.0 8.2e-73 244.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAG02678.1 - 1.1e-09 38.2 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02678.1 - 1.3e-09 38.6 0.0 2.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02678.1 - 1.7e-05 25.3 0.0 2.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG02678.1 - 5.1e-05 22.7 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG02678.1 - 8.5e-05 22.4 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG02678.1 - 0.00027 20.5 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG02678.1 - 0.0003 20.8 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG02678.1 - 0.00074 19.0 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 OAG02678.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.12 OAG02678.1 - 0.0028 18.4 0.0 0.005 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAG02678.1 - 0.019 16.0 0.1 0.12 13.4 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 OAG02678.1 - 0.045 13.9 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Fibrillarin PF01269.17 OAG02678.1 - 0.055 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_4 PF02390.17 OAG02678.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.20 OAG02678.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 OAG02678.1 - 0.24 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW T3SS_ExsE PF18286.1 OAG02679.1 - 0.0048 16.8 0.2 0.015 15.2 0.2 1.9 1 0 0 1 1 1 1 Type III secretion system ExsE AAA_13 PF13166.6 OAG02679.1 - 0.013 14.2 7.8 0.017 13.8 7.8 1.2 1 0 0 1 1 1 0 AAA domain YlqD PF11068.8 OAG02679.1 - 0.036 14.4 1.7 0.036 14.4 1.7 2.8 1 1 1 2 2 2 0 YlqD protein Adeno_E1B_55K_N PF04623.12 OAG02679.1 - 0.17 12.6 1.6 0.51 11.1 1.6 1.8 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus Spc29 PF17082.5 OAG02679.1 - 0.27 11.0 9.6 2.5 7.9 2.4 3.0 1 1 1 2 2 2 0 Spindle Pole Component 29 FlxA PF14282.6 OAG02679.1 - 0.66 10.0 12.5 0.59 10.1 8.2 2.8 2 1 1 3 3 3 0 FlxA-like protein SlyX PF04102.12 OAG02679.1 - 3.4 8.4 22.9 0.38 11.4 2.5 4.3 3 3 1 4 4 4 0 SlyX PilJ PF13675.6 OAG02679.1 - 4.4 7.4 17.1 0.027 14.5 4.0 3.1 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF572 PF04502.13 OAG02679.1 - 4.5 6.8 14.9 4.7 6.7 13.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) Seryl_tRNA_N PF02403.22 OAG02679.1 - 7 6.9 11.9 2.6 8.3 0.4 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HET PF06985.11 OAG02680.1 - 9.7e-33 113.6 0.7 1.5e-32 113.0 0.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PGA2 PF07543.12 OAG02683.1 - 0.49 10.4 6.3 20 5.2 5.6 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 HATPase_c PF02518.26 OAG02684.1 - 8.4e-23 81.0 0.1 2.4e-22 79.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG02684.1 - 6.6e-18 64.9 0.0 1.5e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG02684.1 - 2.8e-12 46.5 0.0 1.1e-11 44.6 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OAG02684.1 - 0.073 12.9 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 OAG02684.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 GHKL domain eIF2A PF08662.11 OAG02685.1 - 5.5e-82 274.4 0.2 9.8e-81 270.3 0.1 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OAG02685.1 - 0.002 18.9 3.6 1.2 10.1 0.1 4.8 5 1 0 5 5 5 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 OAG02685.1 - 0.03 12.9 0.0 0.15 10.6 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 OAG02685.1 - 0.15 12.0 2.7 47 4.1 0.1 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat YccV-like PF08755.11 OAG02686.1 - 5.3e-28 97.4 0.0 1.3e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 OAG02686.1 - 5.1e-18 65.1 0.0 8.2e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 OAG02686.1 - 3e-11 43.0 0.8 6.1e-11 42.0 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG02686.1 - 7.4e-07 28.9 0.1 1.6e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 OAG02686.1 - 0.00015 22.2 0.0 0.00032 21.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 OAG02686.1 - 0.00086 19.2 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 F-box I-set PF07679.16 OAG02687.1 - 0.00054 20.0 0.6 24 5.1 0.0 5.5 6 0 0 6 6 6 2 Immunoglobulin I-set domain DUF5011 PF16403.5 OAG02687.1 - 0.0037 17.4 0.6 0.032 14.4 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF5011) MBG_2 PF18676.1 OAG02687.1 - 9.3 7.0 10.1 1.9 9.2 0.2 4.1 5 0 0 5 5 5 0 MBG domain (YGX type) Peptidase_C12 PF01088.21 OAG02688.1 - 5.3e-51 173.4 0.2 1.1e-50 172.3 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 adh_short PF00106.25 OAG02690.1 - 2.3e-17 63.1 0.0 3.5e-16 59.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02690.1 - 9.8e-14 51.5 0.0 7.5e-13 48.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG02690.1 - 0.0052 16.7 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 KR domain zf-HIT PF04438.16 OAG02691.1 - 4.8e-09 35.9 4.8 7.3e-09 35.3 4.8 1.3 1 0 0 1 1 1 1 HIT zinc finger DDE_Tnp_4 PF13359.6 OAG02691.1 - 0.061 13.0 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Abhydrolase_2 PF02230.16 OAG02692.1 - 2.1e-32 112.7 0.0 2.8e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Cutinase PF01083.22 OAG02692.1 - 0.05 13.6 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Cutinase Hydrolase_4 PF12146.8 OAG02692.1 - 0.14 11.4 0.1 15 4.8 0.0 2.7 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Glyco_hydro_47 PF01532.20 OAG02693.1 - 6.7e-175 582.4 0.4 7.8e-175 582.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 OAG02693.1 - 0.059 11.9 0.0 0.13 10.7 0.0 1.6 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 CRAL_TRIO PF00650.20 OAG02694.1 - 2.1e-25 89.3 0.0 2.9e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG02694.1 - 8.8e-10 38.6 0.1 2.4e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Shadoo PF14999.6 OAG02694.1 - 0.1 12.7 6.7 0.16 12.1 5.1 2.0 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Ribo_biogen_C PF04034.13 OAG02695.1 - 1.3e-48 163.9 0.1 1.8e-48 163.4 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OAG02695.1 - 6.1e-10 38.8 0.3 1.1e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 OAG02695.1 - 0.055 12.8 21.8 0.099 12.0 21.8 1.4 1 0 0 1 1 1 0 BUD22 WSC PF01822.19 OAG02698.1 - 1.5e-13 50.7 5.0 1.5e-13 50.7 5.0 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 OAG02698.1 - 1.4e-07 30.8 2.8 1.4e-07 30.8 2.8 2.0 2 0 0 2 2 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG02698.1 - 0.00021 21.5 0.3 0.00044 20.4 0.3 1.6 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 OAG02698.1 - 0.0011 19.5 0.3 0.0011 19.5 0.3 2.0 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin CbtA PF09490.10 OAG02698.1 - 0.029 14.1 2.1 0.034 13.9 0.2 1.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Amnionless PF14828.6 OAG02698.1 - 0.03 13.2 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Amnionless DUF4366 PF14283.6 OAG02698.1 - 0.031 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TarH PF02203.15 OAG02698.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue FixQ PF05545.11 OAG02698.1 - 0.036 14.0 0.0 5.8 7.0 0.1 3.1 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ EphA2_TM PF14575.6 OAG02698.1 - 0.06 14.2 0.0 0.13 13.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 OAG02698.1 - 0.07 12.9 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF2207 PF09972.9 OAG02698.1 - 0.071 11.9 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2076 PF09849.9 OAG02698.1 - 0.1 12.7 0.4 0.15 12.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Adeno_E3_CR2 PF02439.15 OAG02698.1 - 0.11 12.2 0.7 0.26 11.1 0.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 OAG02698.1 - 0.13 12.4 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Trp_oprn_chp PF09534.10 OAG02698.1 - 0.22 11.3 6.1 0.073 12.9 1.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3042 PF11240.8 OAG02698.1 - 2 8.5 4.1 0.62 10.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Acetyltransf_3 PF13302.7 OAG02701.1 - 2.2e-22 80.2 0.0 2.7e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG02701.1 - 6e-05 23.3 0.0 0.0034 17.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAG02701.1 - 0.0059 16.8 0.0 0.064 13.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Desulfoferrodox PF01880.18 OAG02701.1 - 0.023 15.3 0.0 0.038 14.6 0.0 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin Acetyltransf_13 PF13880.6 OAG02702.1 - 3e-25 88.0 0.0 6.4e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OAG02702.1 - 1e-12 47.6 0.2 2.8e-12 46.3 0.1 1.9 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO CLP_protease PF00574.23 OAG02703.1 - 1.5e-77 259.6 0.0 1.7e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Clp protease Clr5 PF14420.6 OAG02703.1 - 0.029 14.6 0.2 0.05 13.8 0.2 1.4 1 0 0 1 1 1 0 Clr5 domain SDH_sah PF01972.16 OAG02703.1 - 0.081 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase RRG8 PF17068.5 OAG02704.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial YqgB PF11036.8 OAG02704.1 - 0.1 12.4 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Virulence promoting factor CheW PF01584.19 OAG02704.1 - 0.2 11.3 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 CheW-like domain Cupin_2 PF07883.11 OAG02705.1 - 6.8e-09 35.3 0.2 1.2e-08 34.6 0.2 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG02705.1 - 0.00061 19.7 0.1 0.00081 19.3 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG02705.1 - 0.00062 19.4 0.1 0.001 18.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 OAG02705.1 - 0.014 15.0 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 OAG02705.1 - 0.018 14.7 0.5 0.021 14.5 0.5 1.2 1 0 0 1 1 1 0 Cupin Cupin_7 PF12973.7 OAG02705.1 - 0.028 14.3 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain adh_short PF00106.25 OAG02706.1 - 3e-13 49.7 0.0 1.2e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG02706.1 - 2.5e-07 30.8 0.0 3.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG02706.1 - 9.7e-06 25.3 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 OAG02707.1 - 5.5e-72 243.0 0.0 6.6e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 OAG02708.1 - 6.9e-07 29.9 0.0 1.3e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02708.1 - 9.6e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG02708.1 - 2.8e-05 24.0 0.0 6.7e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02708.1 - 0.00025 21.8 0.0 0.00044 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 OAG02708.1 - 0.0064 16.3 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Peptidase_M13_N PF05649.13 OAG02709.1 - 7.5e-96 322.1 0.1 1.1e-95 321.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OAG02709.1 - 3.2e-62 209.8 1.0 4.7e-62 209.2 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M13 Cation_ATPase_C PF00689.21 OAG02710.1 - 4.5e-44 150.3 5.3 4.5e-44 150.3 5.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAG02710.1 - 4e-36 124.2 3.6 4e-36 124.2 3.6 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 OAG02710.1 - 4.1e-21 76.3 0.0 2.9e-09 37.5 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG02710.1 - 3.5e-18 65.5 0.0 6.6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG02710.1 - 3e-12 46.1 0.0 8.1e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG02710.1 - 8.8e-05 22.4 0.1 0.00032 20.5 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 OAG02710.1 - 1.3 7.7 5.5 4.9 5.8 0.3 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Glyco_hydro_79C PF16862.5 OAG02711.1 - 3.1e-17 63.3 3.1 2e-16 60.8 0.1 2.7 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Ank_4 PF13637.6 OAG02712.1 - 0.016 15.8 0.0 0.03 14.9 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG02712.1 - 0.15 12.7 0.0 0.34 11.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat DUF1618 PF07762.14 OAG02713.1 - 0.15 12.7 0.0 0.29 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1618) Sulfotransfer_4 PF17784.1 OAG02714.1 - 2.2e-66 223.7 0.6 2.7e-66 223.5 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG02714.1 - 7.5e-05 23.2 1.1 0.24 11.8 0.4 2.4 1 1 1 2 2 2 2 Sulfotransferase family AA_permease_2 PF13520.6 OAG02715.1 - 1.7e-45 155.6 50.3 2.1e-45 155.4 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG02715.1 - 2.2e-24 85.9 31.1 2.2e-24 85.9 31.1 1.6 2 0 0 2 2 2 1 Amino acid permease DUF5463 PF17551.2 OAG02715.1 - 0.6 10.1 2.9 1.9 8.5 2.9 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5463) MIG-14_Wnt-bd PF06664.12 OAG02716.1 - 0.25 10.5 6.0 0.35 10.1 4.9 1.8 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Acetyltransf_1 PF00583.25 OAG02717.1 - 8.2e-10 38.9 0.0 1.7e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG02717.1 - 9.3e-10 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG02717.1 - 6.9e-09 36.0 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG02717.1 - 0.0079 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG02717.1 - 0.0091 16.0 0.0 0.023 14.6 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Lipase_GDSL_2 PF13472.6 OAG02719.1 - 9.1e-11 42.5 1.2 1.2e-10 42.1 1.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lumazine_bd_2 PF12893.7 OAG02720.1 - 0.01 16.5 0.1 0.014 16.0 0.1 1.3 1 0 0 1 1 1 0 Putative lumazine-binding Pro_isomerase PF00160.21 OAG02721.1 - 2.3e-49 167.7 0.2 3.2e-49 167.2 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MFS_1 PF07690.16 OAG02722.1 - 7e-32 110.7 75.0 5.3e-23 81.5 37.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_61 PF03443.14 OAG02725.1 - 3.7e-62 209.9 0.1 4.5e-62 209.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PKD PF00801.20 OAG02725.1 - 0.079 12.8 0.8 0.37 10.7 0.8 2.3 1 1 0 1 1 1 0 PKD domain GFA PF04828.14 OAG02726.1 - 3.3e-15 56.2 1.8 4.5e-15 55.8 1.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CDC37_N PF03234.14 OAG02727.1 - 1.3e-47 161.9 2.2 1.3e-47 161.9 2.2 2.9 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 OAG02727.1 - 2e-43 147.1 0.1 5.7e-43 145.6 0.0 1.8 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 OAG02727.1 - 3.8e-31 107.2 0.5 1.2e-30 105.5 0.5 1.9 1 0 0 1 1 1 1 Cdc37 C terminal domain CTD_bind PF04818.13 OAG02728.1 - 1e-16 61.5 0.0 3.1e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 OAG02728.1 - 0.001 19.3 0.1 0.0025 18.0 0.1 1.6 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Clathrin_lg_ch PF01086.17 OAG02729.1 - 2.6e-73 246.9 0.6 2.9e-73 246.7 0.6 1.0 1 0 0 1 1 1 1 Clathrin light chain SPR1 PF15356.6 OAG02729.1 - 0.011 16.2 0.4 0.019 15.5 0.4 1.3 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 rve_3 PF13683.6 OAG02729.1 - 0.034 13.9 0.5 0.073 12.9 0.5 1.5 1 0 0 1 1 1 0 Integrase core domain SabA_adhesion PF18304.1 OAG02729.1 - 0.065 12.5 1.0 0.6 9.3 1.1 2.0 2 0 0 2 2 2 0 SabA N-terminal extracellular adhesion domain CENP-T_C PF15511.6 OAG02730.1 - 4.3e-09 36.5 0.1 5.1e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAG02730.1 - 1.2e-05 25.6 0.2 1.4e-05 25.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 OAG02730.1 - 4e-05 23.7 0.2 5.8e-05 23.2 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OAG02730.1 - 6.2e-05 23.2 0.1 0.00011 22.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAG02730.1 - 0.00016 22.0 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OAG02730.1 - 0.0036 17.4 0.0 0.0043 17.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG02730.1 - 0.0062 16.5 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 OAG02730.1 - 0.027 14.3 0.2 0.033 14.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 OAG02730.1 - 0.064 13.8 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 OAG02730.1 - 0.073 13.1 0.0 0.081 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region CDH-cyt PF16010.5 OAG02732.1 - 4.3e-21 75.4 0.2 4.1e-20 72.2 0.1 2.1 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 OAG02732.1 - 0.0014 18.4 0.6 0.0014 18.4 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 OAG02732.1 - 0.0049 17.0 1.4 0.28 11.3 1.2 2.6 1 1 0 2 2 2 1 Protein of unknown function (DUF4079) DOMON PF03351.17 OAG02732.1 - 0.0054 16.9 0.0 0.0092 16.2 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Phage_T4_gp36 PF03903.13 OAG02732.1 - 0.18 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Phage T4 tail fibre DUF2070 PF09843.9 OAG02732.1 - 0.2 9.9 10.4 0.32 9.2 10.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GAS PF13851.6 OAG02733.1 - 0.00075 18.9 5.2 0.0012 18.2 5.2 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 OAG02733.1 - 0.0011 19.4 8.1 0.0016 18.9 8.1 1.2 1 0 0 1 1 1 1 Fez1 Leu_zip PF15294.6 OAG02733.1 - 0.0036 16.9 7.4 0.0065 16.0 7.4 1.4 1 1 0 1 1 1 1 Leucine zipper ADIP PF11559.8 OAG02733.1 - 0.0059 16.7 4.7 0.0084 16.2 4.7 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 OAG02733.1 - 0.017 14.6 6.0 0.026 14.0 6.0 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal GrpE PF01025.19 OAG02733.1 - 0.028 14.1 3.9 0.042 13.5 3.9 1.4 1 0 0 1 1 1 0 GrpE ATG16 PF08614.11 OAG02733.1 - 0.035 14.3 3.4 0.035 14.3 3.4 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 OAG02733.1 - 0.042 13.9 0.2 0.12 12.4 0.0 1.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 OAG02733.1 - 0.06 13.4 6.3 0.05 13.7 3.8 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Csm1_N PF18504.1 OAG02733.1 - 0.064 13.6 3.6 0.13 12.6 3.1 1.9 1 1 0 1 1 1 0 Csm1 N-terminal domain DUF4407 PF14362.6 OAG02733.1 - 0.097 12.0 7.3 0.12 11.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 OAG02733.1 - 0.099 13.0 9.5 0.34 11.3 9.5 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_1 PF00170.21 OAG02733.1 - 0.11 12.6 5.7 0.52 10.4 5.7 2.2 1 1 0 1 1 1 0 bZIP transcription factor TMF_TATA_bd PF12325.8 OAG02733.1 - 0.2 11.9 5.1 0.35 11.1 5.1 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DASH_Spc19 PF08287.11 OAG02733.1 - 0.21 11.5 7.0 1.3 8.9 6.7 2.0 1 1 1 2 2 2 0 Spc19 XhlA PF10779.9 OAG02733.1 - 0.23 11.7 5.9 0.65 10.2 0.6 2.5 1 1 1 2 2 2 0 Haemolysin XhlA DUF724 PF05266.14 OAG02733.1 - 0.25 11.2 3.0 0.34 10.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HrpB7 PF09486.10 OAG02733.1 - 0.26 11.6 8.5 0.061 13.7 4.6 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 OAG02733.1 - 0.55 9.1 6.1 0.7 8.7 6.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 OAG02733.1 - 0.64 10.7 3.6 1.1 9.9 3.1 1.7 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 OAG02733.1 - 0.75 10.3 7.6 2.4 8.7 7.6 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DUF4404 PF14357.6 OAG02733.1 - 1.6 9.4 4.6 6.5 7.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 OAG02733.1 - 2.9 7.1 5.0 0.64 9.2 2.1 1.3 2 0 0 2 2 2 0 TMPIT-like protein DUF4337 PF14235.6 OAG02733.1 - 5.9 7.0 6.0 14 5.7 5.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) ArAE_2_N PF10337.9 OAG02734.1 - 5.4e-43 147.7 30.6 2.6e-34 119.1 0.7 5.2 3 1 2 6 6 6 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAG02734.1 - 9.8e-17 61.3 13.2 9.8e-17 61.3 13.2 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAG02734.1 - 6.7e-12 45.7 0.0 4.3e-11 43.1 0.0 2.3 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 Utp8 PF10395.9 OAG02735.1 - 1.4e-18 66.9 0.7 4.2e-15 55.3 1.4 3.4 2 1 0 2 2 2 2 Utp8 family ANAPC1 PF12859.7 OAG02735.1 - 1.6 9.3 4.3 7.3 7.2 0.6 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Rad17 PF03215.15 OAG02736.1 - 2.4e-06 27.6 0.2 1.5e-05 25.0 0.0 2.3 3 0 0 3 3 3 1 Rad17 P-loop domain AAA PF00004.29 OAG02736.1 - 3.4e-06 27.5 0.0 2.4e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG02736.1 - 0.00016 22.1 0.2 0.00052 20.4 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 OAG02736.1 - 0.0063 17.1 0.0 0.019 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG02736.1 - 0.026 14.9 0.5 0.091 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 OAG02736.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 OAG02736.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OAG02736.1 - 0.049 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OAG02736.1 - 0.074 13.3 0.1 0.22 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG02736.1 - 0.093 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 OAG02736.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAG02736.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAG02736.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG02736.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG02736.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Alb1 PF09135.11 OAG02737.1 - 2e-20 73.6 13.0 3e-20 73.0 13.0 1.3 1 0 0 1 1 1 1 Alb1 Nucleo_P87 PF07267.11 OAG02737.1 - 0.29 10.0 1.0 0.33 9.8 1.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NAD_binding_10 PF13460.6 OAG02738.1 - 2.9e-15 56.6 0.1 5.7e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG02738.1 - 1.3e-10 41.2 0.1 1.7e-10 40.9 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG02738.1 - 7e-07 29.6 0.8 1.7e-06 28.3 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG02738.1 - 0.00048 19.7 0.0 0.00081 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG02738.1 - 0.0012 19.2 0.0 0.0042 17.5 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG02738.1 - 0.0017 18.5 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 OAG02738.1 - 0.022 15.5 1.0 0.045 14.5 0.2 2.1 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_3 PF03447.16 OAG02738.1 - 0.025 15.2 0.1 0.093 13.4 0.0 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG02738.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ADK PF00406.22 OAG02739.1 - 0.034 14.2 0.1 0.14 12.3 0.1 1.8 1 1 0 1 1 1 0 Adenylate kinase RCDG1 PF15725.5 OAG02741.1 - 4.8 7.7 10.8 7.9 7.0 10.8 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein AMP-binding PF00501.28 OAG02742.1 - 1.2e-39 136.1 0.0 1.7e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG02742.1 - 4.5e-07 29.7 3.4 1.5e-06 28.0 0.0 2.8 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG02742.1 - 0.00019 22.3 0.0 0.00045 21.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 OAG02743.1 - 8.6e-11 41.7 0.0 2.1e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02743.1 - 0.00037 20.1 0.1 0.07 12.7 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF3328 PF11807.8 OAG02744.1 - 1.9e-32 112.9 2.1 2.1e-32 112.7 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2271 PF10029.9 OAG02744.1 - 0.16 11.6 0.4 0.28 10.8 0.4 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Insulin_TMD PF17870.1 OAG02746.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Methyltransf_23 PF13489.6 OAG02747.1 - 5.9e-05 23.0 0.0 9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02747.1 - 0.00014 22.4 0.0 0.00028 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02747.1 - 0.0017 19.1 0.0 0.0027 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02747.1 - 0.028 15.0 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 OAG02747.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Aa_trans PF01490.18 OAG02748.1 - 8.9e-23 80.6 34.4 1.1e-22 80.3 34.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RBP_receptor PF14752.6 OAG02748.1 - 0.0039 15.8 2.8 0.0081 14.8 2.8 1.5 1 0 0 1 1 1 1 Retinol binding protein receptor DUF2208 PF09973.9 OAG02748.1 - 4.4 6.8 7.4 0.27 10.8 0.9 2.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) Asp PF00026.23 OAG02751.1 - 1.6e-11 44.2 0.0 2.5e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease PTP_tm PF18861.1 OAG02751.1 - 0.0008 19.5 0.1 0.0018 18.3 0.1 1.6 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 OAG02751.1 - 0.0015 17.9 10.9 0.0033 16.8 10.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 OAG02751.1 - 0.0066 15.4 0.4 0.01 14.7 0.4 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 OAG02751.1 - 0.0082 15.9 0.5 0.015 15.0 0.5 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OAG02751.1 - 0.0089 16.9 0.0 0.018 15.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 OAG02751.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4690 PF15756.5 OAG02751.1 - 0.12 13.0 0.0 0.53 10.9 0.0 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Amnionless PF14828.6 OAG02751.1 - 0.2 10.4 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless CYYR1 PF10873.8 OAG02751.1 - 0.29 11.6 0.8 0.56 10.6 0.1 1.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Prp19 PF08606.11 OAG02753.1 - 4.1e-35 119.6 2.4 4.1e-35 119.6 2.4 1.7 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 OAG02753.1 - 4.4e-10 40.0 10.3 0.012 16.5 0.0 5.3 6 0 0 6 6 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG02753.1 - 4.8e-09 36.4 0.0 0.13 12.6 0.0 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG02753.1 - 0.00051 19.5 0.0 0.025 13.9 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain U-box PF04564.15 OAG02753.1 - 0.002 18.3 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain V_ATPase_I_N PF18670.1 OAG02753.1 - 0.019 15.3 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain PQQ PF01011.21 OAG02753.1 - 0.041 13.8 0.0 0.16 12.0 0.0 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 OAG02753.1 - 0.051 12.1 0.0 0.17 10.4 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 OAG02753.1 - 0.055 14.0 2.7 10 6.7 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain zf-Nse PF11789.8 OAG02753.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PSII_BNR PF14870.6 OAG02753.1 - 0.076 12.3 0.4 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 VWA_2 PF13519.6 OAG02753.1 - 0.11 13.2 0.2 0.21 12.3 0.2 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain zf-RING_2 PF13639.6 OAG02755.1 - 0.0016 18.7 3.1 0.0039 17.5 3.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG02755.1 - 0.0063 16.5 2.4 0.013 15.5 2.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG02755.1 - 0.0072 16.3 6.4 0.011 15.6 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG02755.1 - 0.14 12.1 3.0 0.28 11.1 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG02755.1 - 0.37 11.0 2.8 1.3 9.3 0.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAG02755.1 - 0.47 10.3 6.3 1.8 8.5 6.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 OAG02755.1 - 2 8.7 9.2 2.9 8.2 4.0 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 OAG02755.1 - 5.2 7.0 8.9 0.83 9.6 1.9 2.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG02755.1 - 6.7 6.7 9.5 0.79 9.6 4.9 1.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PTPLA PF04387.14 OAG02756.1 - 8.9e-58 194.6 9.1 1.3e-57 194.1 9.1 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Glyco_hydro_31 PF01055.26 OAG02757.1 - 6.9e-164 546.2 1.5 8.4e-164 545.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG02757.1 - 9.2e-41 138.7 0.0 1.7e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG02757.1 - 8.3e-15 54.9 1.2 8.3e-15 54.9 1.2 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.16 OAG02758.1 - 1.4e-31 109.8 33.9 1.4e-31 109.8 33.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 OAG02758.1 - 6e-05 21.5 1.9 6e-05 21.5 1.9 1.9 2 0 0 2 2 2 1 BT1 family Steroid_dh PF02544.16 OAG02759.1 - 0.13 12.2 0.0 21 5.1 0.0 2.3 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Adeno_E3B PF03376.14 OAG02759.1 - 0.17 12.2 0.6 0.39 11.0 0.6 1.5 1 0 0 1 1 1 0 Adenovirus E3B protein Phage_holin_3_6 PF07332.11 OAG02759.1 - 3.1 7.9 11.9 1.7 8.7 4.9 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HET PF06985.11 OAG02760.1 - 3.9e-10 40.3 0.1 1.3e-06 28.9 0.0 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TRAPPC10 PF12584.8 OAG02760.1 - 0.0036 17.0 0.2 0.0081 15.9 0.2 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DSS1_SEM1 PF05160.13 OAG02760.1 - 0.19 11.8 1.9 0.48 10.5 1.9 1.7 1 0 0 1 1 1 0 DSS1/SEM1 family TPR_10 PF13374.6 OAG02762.1 - 3.6e-07 29.8 6.1 0.002 17.9 0.2 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG02762.1 - 9.4e-07 29.0 11.0 0.0024 18.1 1.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG02762.1 - 0.00017 21.4 2.7 0.039 14.1 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG02762.1 - 0.0035 17.4 1.8 6.5 7.2 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG02762.1 - 0.004 16.9 0.1 0.3 11.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat HEPN PF05168.14 OAG02762.1 - 0.021 15.0 0.1 0.095 12.8 0.0 2.0 2 0 0 2 2 2 0 HEPN domain Vps23_core PF09454.10 OAG02762.1 - 0.032 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Vps23 core domain TPR_7 PF13176.6 OAG02762.1 - 0.064 13.3 1.9 0.54 10.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG02762.1 - 0.23 12.0 1.4 29 5.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG02762.1 - 0.38 11.4 5.6 2.5 8.8 1.6 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG02762.1 - 1.1 10.2 5.0 1.2 10.1 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Thioredoxin PF00085.20 OAG02763.1 - 6.6e-26 90.3 0.1 9.1e-26 89.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG02763.1 - 1.1e-06 28.2 0.1 1.2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAG02763.1 - 4.5e-06 26.9 0.0 0.00063 20.0 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OAG02763.1 - 1.8e-05 25.2 1.0 0.00047 20.6 0.5 2.5 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OAG02763.1 - 0.0014 18.4 0.1 0.0019 18.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OAG02763.1 - 0.0019 18.1 0.2 0.0051 16.7 0.1 1.7 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OAG02763.1 - 0.0066 16.2 0.1 0.015 15.0 0.1 1.6 1 1 1 2 2 2 1 Redoxin Thioredoxin_3 PF13192.6 OAG02763.1 - 0.024 14.7 0.3 0.15 12.1 0.0 2.0 1 1 0 2 2 2 0 Thioredoxin domain Thioredoxin_7 PF13899.6 OAG02763.1 - 0.037 14.2 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.11 OAG02763.1 - 0.037 13.6 0.1 0.42 10.3 0.1 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TrbC_Ftype PF09673.10 OAG02763.1 - 0.037 14.1 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_4 PF13462.6 OAG02763.1 - 0.042 14.0 0.1 4.2 7.5 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 OAG02763.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 Glutaredoxin DUF1390 PF07150.11 OAG02763.1 - 0.098 12.4 0.2 0.12 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) KaiB PF07689.12 OAG02763.1 - 0.15 11.8 0.1 0.32 10.8 0.1 1.6 1 1 0 1 1 1 0 KaiB domain Thioredoxin PF00085.20 OAG02764.1 - 9.5e-60 199.0 0.4 9.3e-31 105.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OAG02764.1 - 8.6e-22 77.9 4.2 1e-21 77.6 1.5 2.4 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 OAG02764.1 - 7e-17 61.9 0.6 3.6e-07 30.6 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OAG02764.1 - 1.5e-15 57.4 0.0 2.1e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAG02764.1 - 3.7e-09 36.8 0.1 0.0025 18.1 0.0 3.9 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 OAG02764.1 - 3e-08 33.7 0.0 0.0046 17.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 OAG02764.1 - 1.9e-07 31.0 0.5 0.0081 16.1 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 OAG02764.1 - 1.2e-06 28.6 0.0 0.041 13.8 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain ERp29_N PF07912.13 OAG02764.1 - 4.3e-06 26.9 0.1 0.039 14.1 0.0 2.3 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 OAG02764.1 - 1.2e-05 25.1 0.0 0.0079 16.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 OAG02764.1 - 2.7e-05 24.1 0.0 0.042 13.7 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 OAG02764.1 - 5e-05 23.0 0.5 0.088 12.5 0.0 2.3 2 0 0 2 2 2 2 Redoxin Glutaredoxin PF00462.24 OAG02764.1 - 0.0001 22.5 0.2 0.049 13.9 0.0 3.1 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.6 OAG02764.1 - 0.00012 22.1 0.0 1 9.5 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin domain HyaE PF07449.11 OAG02764.1 - 0.00024 21.0 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 OAG02764.1 - 0.0021 18.2 4.1 3.7 7.7 0.1 4.1 3 2 1 4 4 4 1 Thioredoxin DUF836 PF05768.14 OAG02764.1 - 0.0039 17.6 0.0 0.99 9.9 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) DDE_Tnp_1_2 PF13586.6 OAG02764.1 - 0.045 14.1 0.0 0.95 9.9 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain YABBY PF04690.13 OAG02764.1 - 0.11 13.1 0.0 21 5.7 0.0 2.3 2 0 0 2 2 2 0 YABBY protein HSBP1 PF06825.12 OAG02765.1 - 3.9e-19 68.2 1.7 4.7e-19 68.0 1.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 OAG02765.1 - 0.0055 16.5 4.0 0.033 14.1 4.0 1.9 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 OAG02765.1 - 0.013 15.9 0.4 0.017 15.6 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 OAG02765.1 - 0.013 15.3 0.2 0.014 15.3 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3510 PF12022.8 OAG02765.1 - 0.014 15.7 0.1 0.015 15.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Baculo_PEP_C PF04513.12 OAG02765.1 - 0.027 14.5 1.2 0.032 14.3 1.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Corona_S2 PF01601.16 OAG02765.1 - 0.029 12.9 0.4 0.033 12.7 0.4 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Cortex-I_coil PF09304.10 OAG02765.1 - 0.029 14.6 0.2 0.034 14.4 0.2 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil CLZ PF16526.5 OAG02765.1 - 0.035 14.5 0.4 0.043 14.2 0.4 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_min_cap2 PF06152.11 OAG02765.1 - 0.048 12.6 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Fzo_mitofusin PF04799.13 OAG02765.1 - 0.07 12.7 0.3 0.084 12.4 0.3 1.0 1 0 0 1 1 1 0 fzo-like conserved region Trimer_CC PF08954.11 OAG02765.1 - 0.51 9.9 0.0 0.51 9.9 0.0 2.2 2 1 0 2 2 2 0 Trimerisation motif Ebp2 PF05890.12 OAG02766.1 - 2e-95 319.4 18.8 2e-95 319.4 18.8 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 SMC_ScpA PF02616.14 OAG02766.1 - 0.41 10.5 3.4 0.71 9.7 3.4 1.3 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Methyltransf_34 PF11312.8 OAG02768.1 - 5.2e-112 374.0 0.0 6e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Xpo1 PF08389.12 OAG02768.1 - 0.054 13.6 0.2 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Exportin 1-like protein CheR PF01739.18 OAG02768.1 - 0.058 12.9 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain WD40 PF00400.32 OAG02769.1 - 7.4e-26 89.9 4.9 3.3e-06 27.7 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG02769.1 - 0.00035 20.8 0.0 8.6 6.7 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG02769.1 - 0.071 11.7 0.4 3.5 6.1 0.0 2.5 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Ribonuc_red_sm PF00268.21 OAG02770.1 - 7.2e-122 406.2 0.6 9.4e-122 405.8 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RNA_pol_Rpc4 PF05132.14 OAG02772.1 - 8.5e-29 100.9 0.0 8.5e-29 100.9 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 Arm PF00514.23 OAG02773.1 - 1.5e-74 243.9 34.4 7.6e-13 48.0 0.2 11.6 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAG02773.1 - 9.5e-20 70.7 17.1 5.3e-06 26.8 0.2 8.2 7 3 2 9 9 9 6 HEAT-like repeat HEAT_2 PF13646.6 OAG02773.1 - 4.2e-19 68.7 10.7 3.3e-07 30.6 0.0 7.0 3 3 4 7 7 7 3 HEAT repeats HEAT PF02985.22 OAG02773.1 - 4.3e-16 57.6 17.8 0.074 13.4 0.2 9.6 10 1 1 11 11 11 4 HEAT repeat KAP PF05804.12 OAG02773.1 - 8.3e-13 47.4 1.3 9.8e-13 47.2 0.5 1.5 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 OAG02773.1 - 1.4e-11 43.7 10.8 1.5e-07 30.4 1.0 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 OAG02773.1 - 1.9e-11 43.9 5.2 6.5e-07 29.1 2.0 2.5 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 OAG02773.1 - 1.1e-08 34.8 2.8 1.3e-05 24.6 0.8 3.4 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 OAG02773.1 - 3.6e-06 27.1 9.4 0.0038 17.3 0.2 5.3 1 1 5 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OAG02773.1 - 1.4e-05 25.1 7.4 0.2 11.6 0.1 4.3 1 1 4 5 5 5 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 OAG02773.1 - 0.00048 20.2 3.7 3.1 7.9 0.1 4.8 2 1 6 8 8 8 1 V-ATPase subunit H DAP_B PF07930.12 OAG02773.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 D-aminopeptidase, domain B Atx10homo_assoc PF09759.9 OAG02773.1 - 0.007 16.4 6.6 0.84 9.7 0.1 4.8 3 1 3 6 6 6 1 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.9 OAG02773.1 - 0.0079 14.8 3.7 0.37 9.2 0.2 3.2 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 OAG02773.1 - 0.015 15.5 4.4 10 6.3 0.0 4.7 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 OAG02773.1 - 0.024 15.3 10.2 9.7 7.2 0.8 6.6 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 OAG02773.1 - 0.026 14.5 2.7 5.8 6.9 0.1 3.4 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 OAG02773.1 - 0.086 13.4 0.0 5.7 7.6 0.0 3.4 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region IBB PF01749.20 OAG02773.1 - 0.24 11.9 0.8 19 5.8 0.1 3.7 3 0 0 3 3 3 0 Importin beta binding domain Pkinase PF00069.25 OAG02774.1 - 2.4e-45 154.9 0.0 3.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG02774.1 - 6.1e-27 94.5 0.0 2.9e-26 92.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG02774.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CLN3 PF02487.17 OAG02774.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 CLN3 protein DUF5127 PF17168.4 OAG02776.1 - 3.4e-80 269.1 6.4 5.8e-80 268.3 6.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 OAG02776.1 - 1e-77 259.7 1.2 2.3e-77 258.6 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 OAG02776.1 - 1.7e-61 207.5 0.6 1.7e-61 207.5 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 OAG02776.1 - 0.00011 21.7 0.0 0.00039 19.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) PalH PF08733.10 OAG02780.1 - 1.1e-117 392.8 0.0 1.3e-117 392.5 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 GIIM PF08388.11 OAG02780.1 - 0.1 12.7 0.4 0.28 11.2 0.4 1.7 1 0 0 1 1 1 0 Group II intron, maturase-specific domain PX PF00787.24 OAG02781.1 - 3.7e-17 62.3 0.1 8.4e-17 61.2 0.1 1.6 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.6 OAG02781.1 - 0.031 14.3 2.9 0.063 13.3 0.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit V-SNARE_C PF12352.8 OAG02781.1 - 0.18 12.1 0.2 0.35 11.2 0.2 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Cullin_binding PF03556.15 OAG02782.1 - 1.3e-33 116.0 6.9 1.8e-33 115.5 6.9 1.2 1 0 0 1 1 1 1 Cullin binding Ribosomal_L32e PF01655.18 OAG02783.1 - 1.4e-49 167.0 1.2 1.4e-49 167.0 1.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 Spc7 PF08317.11 OAG02785.1 - 0.13 11.1 7.2 0.33 9.8 0.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OAG02785.1 - 0.13 12.2 11.8 0.94 9.5 2.6 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 OAG02785.1 - 0.38 9.1 7.3 0.43 8.9 0.6 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 OAG02785.1 - 0.38 11.2 6.2 3 8.2 0.4 2.4 2 0 0 2 2 2 0 Fez1 ATG16 PF08614.11 OAG02785.1 - 0.54 10.5 18.4 1.7 8.8 6.7 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Nup54 PF13874.6 OAG02785.1 - 0.87 9.7 12.7 0.71 10.0 4.1 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Vps5 PF09325.10 OAG02785.1 - 0.99 8.9 6.0 0.98 8.9 1.5 2.3 2 0 0 2 2 2 0 Vps5 C terminal like DUF724 PF05266.14 OAG02785.1 - 1.1 9.1 6.6 7 6.4 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF724) APG6_N PF17675.1 OAG02785.1 - 2 8.9 12.3 0.42 11.1 1.1 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region KinB_sensor PF16767.5 OAG02785.1 - 2.1 8.8 7.3 0.42 11.1 0.3 2.6 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF4200 PF13863.6 OAG02785.1 - 3 8.3 10.0 11 6.5 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BST2 PF16716.5 OAG02785.1 - 3.3 8.4 8.2 7.1 7.3 0.1 3.4 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 TMF_TATA_bd PF12325.8 OAG02785.1 - 4.1 7.6 9.9 1.4 9.1 1.2 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 OAG02785.1 - 4.6 7.9 16.6 1.9 9.2 1.1 3.6 2 1 1 3 3 3 0 SlyX TMF_DNA_bd PF12329.8 OAG02785.1 - 5.2 7.1 5.9 15 5.7 0.4 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CCDC144C PF14915.6 OAG02785.1 - 9.5 5.2 14.5 0.46 9.5 2.8 2.3 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region zf-BED PF02892.15 OAG02787.1 - 0.067 13.2 0.8 0.11 12.5 0.8 1.4 1 0 0 1 1 1 0 BED zinc finger Inhibitor_I53 PF11714.8 OAG02788.1 - 0.038 14.2 0.6 0.091 13.0 0.6 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin GA-like PF17573.2 OAG02788.1 - 0.067 13.1 0.5 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 GA-like domain PMT2_N PF17987.1 OAG02789.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Ldh_1_N PF00056.23 OAG02790.1 - 7e-24 84.5 0.7 1e-23 84.0 0.7 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAG02790.1 - 3.2e-17 63.0 0.0 5.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Shikimate_DH PF01488.20 OAG02790.1 - 0.051 13.6 0.6 0.088 12.9 0.6 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4630 PF15443.6 OAG02790.1 - 0.093 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) PPDK_N PF01326.19 OAG02791.1 - 1.1e-106 356.9 0.0 1.6e-106 356.3 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 OAG02791.1 - 1.3e-59 201.7 0.0 2.2e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 OAG02791.1 - 1.9e-24 85.2 1.6 5.3e-24 83.7 1.6 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Amino_oxidase PF01593.24 OAG02793.1 - 2e-59 202.1 0.1 2.4e-59 201.8 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG02793.1 - 9.2e-12 45.0 0.2 2.1e-11 43.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG02793.1 - 1.3e-07 31.6 0.4 1.8e-06 27.8 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG02793.1 - 9.3e-06 25.1 0.2 2.3e-05 23.8 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG02793.1 - 1.3e-05 25.6 0.3 4.3e-05 24.0 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG02793.1 - 6.6e-05 21.8 0.3 0.0016 17.3 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 OAG02793.1 - 9e-05 21.9 0.3 0.00018 20.8 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG02793.1 - 9.2e-05 21.8 0.1 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG02793.1 - 9.4e-05 21.9 1.1 0.00014 21.3 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG02793.1 - 9.5e-05 22.4 0.0 0.0055 16.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG02793.1 - 0.00017 20.8 1.6 0.00017 20.8 1.6 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG02793.1 - 0.0004 19.7 0.1 0.36 10.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG02793.1 - 0.01 15.0 0.4 0.018 14.2 0.4 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FMO-like PF00743.19 OAG02793.1 - 0.018 13.5 0.0 0.026 13.0 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 OAG02793.1 - 0.027 13.8 0.3 0.027 13.8 0.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAG02793.1 - 0.18 10.8 0.3 0.43 9.6 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_4 PF01565.23 OAG02794.1 - 1.3e-15 57.4 0.2 2.1e-15 56.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG02794.1 - 2.5e-05 24.3 0.3 5.8e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like S1 PF00575.23 OAG02795.1 - 3.8e-59 197.0 32.2 1.7e-10 41.1 0.4 12.6 12 0 0 12 12 12 9 S1 RNA binding domain RNase_II_C_S1 PF18614.1 OAG02795.1 - 3.9e-10 39.5 8.2 0.17 11.9 0.0 7.8 7 0 0 7 7 7 2 RNase II-type exonuclease C-terminal S1 domain TPR_19 PF14559.6 OAG02795.1 - 2.1e-05 24.9 0.4 0.033 14.7 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG02795.1 - 0.00036 21.1 3.0 2.6 9.1 0.6 4.7 2 1 2 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 OAG02795.1 - 0.00086 19.4 7.7 0.0038 17.2 0.0 3.4 2 1 0 3 3 3 1 Suppressor of forked protein (Suf) PPR PF01535.20 OAG02795.1 - 0.012 15.8 0.2 0.23 11.8 0.0 3.0 2 0 0 2 2 2 0 PPR repeat D-ser_dehydrat PF14031.6 OAG02795.1 - 0.013 16.1 0.2 0.56 10.9 0.0 3.7 4 0 0 4 4 4 0 Putative serine dehydratase domain TPR_16 PF13432.6 OAG02795.1 - 0.019 15.6 0.1 22 5.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 OAG02795.1 - 0.02 15.1 0.1 0.083 13.1 0.0 2.1 2 0 0 2 2 2 0 PPR repeat family NRDE-2 PF08424.10 OAG02795.1 - 0.022 13.9 0.3 0.087 11.9 0.3 2.0 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference Wzy_C_2 PF11846.8 OAG02795.1 - 0.039 13.9 0.1 0.089 12.7 0.1 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal AEP1 PF17049.5 OAG02795.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 ATPase expression protein 1 SH3_2 PF07653.17 OAG02795.1 - 0.19 11.4 3.9 5.9 6.7 0.0 4.5 6 0 0 6 6 6 0 Variant SH3 domain DNA_pol_phi PF04931.13 OAG02795.1 - 7.6 4.5 38.1 0.12 10.4 5.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi WD40 PF00400.32 OAG02796.1 - 4.7e-13 49.4 20.5 0.0049 17.7 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG02796.1 - 2.5e-07 30.9 0.4 0.0066 16.7 0.1 4.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG02796.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain ESCRT-II PF05871.12 OAG02797.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 ESCRT-II complex subunit DUF4875 PF16175.5 OAG02798.1 - 0.043 13.9 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) MAP65_ASE1 PF03999.12 OAG02799.1 - 1.7e-74 251.6 13.1 1.7e-74 251.6 13.1 2.0 1 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) APG6_N PF17675.1 OAG02799.1 - 0.07 13.7 37.5 0.15 12.6 6.8 3.7 3 1 1 4 4 4 0 Apg6 coiled-coil region Prominin PF05478.11 OAG02799.1 - 0.96 7.3 4.3 1.9 6.4 0.3 2.4 3 0 0 3 3 3 0 Prominin EspB PF05802.11 OAG02799.1 - 0.99 9.4 3.0 0.57 10.1 0.4 1.8 2 0 0 2 2 2 0 Enterobacterial EspB protein Baculo_PEP_C PF04513.12 OAG02799.1 - 1.4 9.0 2.7 6.3 6.8 0.3 3.3 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 OAG02799.1 - 1.4 8.2 14.2 2.6 7.3 5.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1308 PF07000.11 OAG02800.1 - 9e-09 35.5 0.0 1.7e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF3216 PF11505.8 OAG02800.1 - 0.15 12.3 0.0 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) SRP9-21 PF05486.12 OAG02801.1 - 2.7e-31 107.8 1.0 3.9e-31 107.3 1.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) TMEM52 PF14979.6 OAG02801.1 - 0.13 12.1 0.4 0.38 10.6 0.2 1.7 2 0 0 2 2 2 0 Transmembrane 52 HAGH_C PF16123.5 OAG02803.1 - 4.9e-21 75.0 0.2 8.9e-21 74.2 0.2 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OAG02803.1 - 8.2e-18 65.1 1.6 1.1e-16 61.4 1.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Aa_trans PF01490.18 OAG02806.1 - 2.6e-51 174.6 41.0 3e-51 174.4 41.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein p450 PF00067.22 OAG02807.1 - 4.3e-54 184.0 0.0 5.9e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5379 PF17350.2 OAG02808.1 - 0.095 13.0 4.7 0.28 11.5 4.7 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5379) Synaptobrevin PF00957.21 OAG02808.1 - 0.14 12.0 0.4 0.48 10.2 0.4 1.9 1 0 0 1 1 1 0 Synaptobrevin APH PF01636.23 OAG02809.1 - 2e-06 27.9 0.0 3.2e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG02809.1 - 0.13 11.8 0.0 15 5.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Peptidase_S10 PF00450.22 OAG02810.1 - 1.3e-81 275.2 0.3 1.7e-81 274.8 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UL45 PF05473.12 OAG02811.1 - 0.034 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF4190 PF13828.6 OAG02811.1 - 0.098 12.4 2.3 0.17 11.7 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Prominin PF05478.11 OAG02811.1 - 0.61 8.0 2.5 0.79 7.6 2.5 1.0 1 0 0 1 1 1 0 Prominin LPMO_10 PF03067.15 OAG02812.1 - 3e-10 41.1 0.1 3.9e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ABM PF03992.16 OAG02813.1 - 0.00055 20.0 0.1 0.0007 19.7 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FemAB_like PF04339.12 OAG02813.1 - 0.0057 15.8 0.1 0.0067 15.6 0.1 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition OSCP PF00213.18 OAG02813.1 - 0.021 15.0 0.1 0.023 14.8 0.1 1.0 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit ACC_central PF08326.12 OAG02814.1 - 4.2e-279 927.8 0.0 5.2e-279 927.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OAG02814.1 - 3.9e-187 622.8 0.0 6.1e-187 622.2 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAG02814.1 - 1.6e-53 181.4 0.0 5.4e-53 179.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG02814.1 - 4.6e-28 98.0 0.1 9.2e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG02814.1 - 5.9e-23 81.0 0.0 2.9e-20 72.4 0.0 3.1 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG02814.1 - 2.2e-16 59.4 0.0 5.4e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 OAG02814.1 - 0.0014 18.7 0.0 0.0064 16.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAG02814.1 - 0.0017 17.9 0.0 0.0056 16.2 0.0 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GxGYxYP_N PF16216.5 OAG02814.1 - 0.0061 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp PF02222.22 OAG02814.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Mito_carr PF00153.27 OAG02815.1 - 2.7e-44 149.0 0.9 1.3e-14 53.9 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein RapA_C PF12137.8 OAG02815.1 - 0.6 9.1 5.5 0.064 12.3 0.8 1.7 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal Prefoldin_2 PF01920.20 OAG02815.1 - 1.1 9.2 6.6 2.2 8.3 6.6 1.5 1 0 0 1 1 1 0 Prefoldin subunit UPRTase PF14681.6 OAG02817.1 - 1.6e-74 249.8 0.0 1.9e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAG02817.1 - 7.4e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 OAG02817.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding CRCB PF02537.15 OAG02818.1 - 4.4e-36 123.1 9.5 3.6e-22 78.5 5.2 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF4449 PF14613.6 OAG02819.1 - 7.9e-67 224.4 4.4 7.9e-67 224.4 4.4 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) JHBP PF06585.11 OAG02819.1 - 0.037 13.2 2.7 0.1 11.8 2.7 1.7 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) Prp18 PF02840.15 OAG02819.1 - 0.81 9.7 0.0 0.81 9.7 0.0 3.4 2 2 2 4 4 4 0 Prp18 domain Nnf1 PF03980.14 OAG02821.1 - 0.14 12.6 0.2 0.14 12.6 0.2 2.5 1 1 1 2 2 2 0 Nnf1 DUF4672 PF15716.5 OAG02821.1 - 0.62 9.7 6.2 0.34 10.5 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4672) RRM_1 PF00076.22 OAG02822.1 - 1.2e-11 44.2 0.1 2.1e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF20 PF17052.5 OAG02822.1 - 1.2 9.3 8.0 0.061 13.5 0.9 2.2 1 1 1 2 2 2 0 Cap associated factor U79_P34 PF03064.16 OAG02822.1 - 9.8 5.5 7.5 20 4.5 7.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DivIC PF04977.15 OAG02823.1 - 0.06 13.1 1.3 3.4 7.5 1.3 2.2 2 0 0 2 2 2 0 Septum formation initiator TPD52 PF04201.15 OAG02823.1 - 0.2 11.3 5.0 0.27 10.8 5.0 1.2 1 0 0 1 1 1 0 Tumour protein D52 family GPS2_interact PF15784.5 OAG02823.1 - 1.1 9.8 7.6 1.4 9.4 7.3 1.4 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain SAM_2 PF07647.17 OAG02824.1 - 2.1e-15 56.6 0.0 3.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 OAG02824.1 - 3.7e-13 49.9 0.0 7.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 OAG02824.1 - 4.6e-13 49.4 0.0 7.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TMF_TATA_bd PF12325.8 OAG02824.1 - 0.13 12.5 0.7 0.22 11.7 0.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FAM70 PF14967.6 OAG02824.1 - 5.9 6.3 9.2 11 5.4 9.2 1.4 1 0 0 1 1 1 0 FAM70 protein SPX PF03105.19 OAG02824.1 - 6.4 6.6 11.7 1.2 9.0 7.2 1.9 2 0 0 2 2 2 0 SPX domain EnY2 PF10163.9 OAG02825.1 - 0.015 15.6 0.0 0.89 10.0 0.0 2.3 1 1 1 2 2 2 0 Transcription factor e(y)2 Phage_Mu_F PF04233.14 OAG02825.1 - 0.1 13.3 0.1 0.15 12.8 0.1 1.3 1 1 0 1 1 1 0 Phage Mu protein F like protein AAA PF00004.29 OAG02826.1 - 1.6e-97 323.0 0.0 2.8e-47 160.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG02826.1 - 6.6e-22 77.1 3.9 2e-12 46.7 0.2 2.9 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 OAG02826.1 - 1.1e-18 67.1 1.1 2.7e-18 65.9 0.5 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 OAG02826.1 - 4.7e-14 52.9 0.0 1.1e-07 32.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG02826.1 - 6.3e-14 52.0 0.0 6.8e-06 25.9 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG02826.1 - 2.5e-12 47.5 0.0 0.00015 22.2 0.0 4.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 OAG02826.1 - 5.6e-12 46.0 0.0 2.1e-05 24.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 OAG02826.1 - 1.3e-10 41.5 0.6 2e-05 24.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG02826.1 - 4.7e-09 35.9 0.0 0.0013 18.0 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OAG02826.1 - 6.3e-09 36.2 0.4 0.071 13.4 0.1 4.3 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 OAG02826.1 - 2.1e-07 30.6 0.1 5.1e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 OAG02826.1 - 2.6e-07 30.2 0.2 0.15 11.4 0.0 3.4 3 0 0 3 3 3 2 KaiC Mg_chelatase PF01078.21 OAG02826.1 - 4.8e-07 29.4 0.3 0.039 13.3 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG02826.1 - 6.7e-07 29.7 0.0 0.03 14.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OAG02826.1 - 7.3e-07 29.1 0.0 0.026 14.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 OAG02826.1 - 1.5e-06 28.8 0.0 0.057 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 OAG02826.1 - 2.1e-06 27.6 0.1 2.1e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 OAG02826.1 - 2.4e-06 27.3 3.9 0.76 9.3 0.1 4.8 3 2 1 5 5 5 2 AAA domain AAA_14 PF13173.6 OAG02826.1 - 3e-06 27.3 0.0 0.017 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OAG02826.1 - 6.8e-06 25.7 0.0 0.049 13.1 0.0 3.1 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OAG02826.1 - 2e-05 24.4 0.0 0.14 11.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 OAG02826.1 - 3e-05 23.3 0.1 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OAG02826.1 - 3e-05 23.3 0.0 0.022 13.9 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 OAG02826.1 - 4e-05 23.9 0.0 0.31 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 OAG02826.1 - 5e-05 23.1 0.1 0.44 10.2 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 OAG02826.1 - 7.1e-05 22.8 0.0 0.25 11.1 0.0 3.1 4 0 0 4 4 3 2 Bacterial dnaA protein ABC_tran PF00005.27 OAG02826.1 - 0.00012 22.6 0.0 0.43 11.1 0.0 3.4 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.16 OAG02826.1 - 0.00019 20.9 0.4 0.47 9.9 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein TsaE PF02367.17 OAG02826.1 - 0.00024 21.1 0.0 0.82 9.7 0.0 2.8 2 1 1 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OAG02826.1 - 0.00025 21.5 0.1 0.61 10.5 0.0 3.3 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 OAG02826.1 - 0.00043 20.3 0.0 0.078 13.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 OAG02826.1 - 0.00051 19.9 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 OAG02826.1 - 0.00059 19.7 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAG02826.1 - 0.00073 18.9 0.0 0.91 8.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 OAG02826.1 - 0.0014 18.6 0.0 2.4 8.0 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 OAG02826.1 - 0.0025 17.8 0.1 1.3 8.9 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 OAG02826.1 - 0.0025 17.6 0.4 2.2 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAG02826.1 - 0.01 15.6 0.0 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OAG02826.1 - 0.011 15.0 0.0 2.1 7.5 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 OAG02826.1 - 0.013 15.9 1.2 9.3 6.6 0.0 3.4 3 1 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 OAG02826.1 - 0.019 14.9 0.5 4.2 7.3 0.0 3.6 3 0 0 3 3 3 0 NTPase KAP_NTPase PF07693.14 OAG02826.1 - 0.02 14.2 0.2 0.94 8.7 0.0 2.8 2 2 0 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.12 OAG02826.1 - 0.023 14.0 0.0 6.2 6.0 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 OAG02826.1 - 0.026 14.7 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain UFD1 PF03152.14 OAG02826.1 - 0.032 13.7 0.0 0.29 10.6 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Zot PF05707.12 OAG02826.1 - 0.032 13.9 0.0 2.1 8.0 0.0 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) IPT PF01745.16 OAG02826.1 - 0.033 13.6 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 OAG02826.1 - 0.097 12.4 0.0 18 5.0 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 OAG02826.1 - 0.098 11.6 0.2 9.3 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region SLAC1 PF03595.17 OAG02827.1 - 4.3e-93 312.1 44.0 4.9e-93 311.9 44.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF21 PF01595.20 OAG02827.1 - 0.82 9.3 14.9 0.13 11.9 0.5 3.4 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain NBD94 PF16830.5 OAG02828.1 - 0.037 14.4 0.5 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH DUF3778 PF12620.8 OAG02828.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) EthD PF07110.11 OAG02829.1 - 1.6e-08 35.6 0.0 1.9e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG02829.1 - 0.014 15.9 0.0 0.019 15.4 0.0 1.3 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Tap-RNA_bind PF09162.10 OAG02829.1 - 0.14 12.0 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 Tap, RNA-binding zf-C2H2 PF00096.26 OAG02830.1 - 1.7e-10 40.7 22.4 0.0012 19.2 2.4 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG02830.1 - 5e-05 23.8 27.5 0.14 13.1 0.2 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG02830.1 - 0.001 19.3 4.1 0.001 19.3 4.1 3.9 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 OAG02830.1 - 0.005 16.7 8.3 0.59 10.0 0.3 4.1 3 1 1 4 4 4 1 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 OAG02830.1 - 0.066 13.7 0.2 0.066 13.7 0.2 5.0 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 OAG02830.1 - 0.087 13.2 19.2 3.5 8.0 0.0 4.1 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 OAG02830.1 - 0.15 12.2 0.2 0.15 12.2 0.2 4.1 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_7 PF15269.6 OAG02830.1 - 0.16 12.1 1.6 0.72 10.0 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger zf_C2H2_ZHX PF18387.1 OAG02830.1 - 4.4 7.0 11.5 34 4.2 0.1 3.8 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 OAG02830.1 - 6.2 7.5 10.6 0.85 10.3 3.0 2.7 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats UCH PF00443.29 OAG02831.1 - 4.1e-34 118.2 0.0 7.5e-34 117.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG02831.1 - 1.4e-07 31.4 0.0 3.7e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PHM7_cyt PF14703.6 OAG02831.1 - 0.044 14.0 0.3 0.044 14.0 0.3 1.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ada3 PF10198.9 OAG02831.1 - 0.14 12.3 1.1 0.34 11.1 1.1 1.5 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF4449 PF14613.6 OAG02831.1 - 0.78 9.8 6.6 1.3 9.1 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Sec2p PF06428.11 OAG02833.1 - 1.3e-11 44.3 16.8 1.6e-11 44.0 11.1 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.9 OAG02833.1 - 0.034 14.4 18.5 0.41 10.8 9.9 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Vac_Fusion PF02346.16 OAG02833.1 - 0.074 12.7 2.0 3 7.5 0.7 2.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 CLZ PF16526.5 OAG02833.1 - 0.27 11.6 17.8 1.6 9.1 0.2 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 OAG02833.1 - 0.5 10.5 21.7 1.9 8.5 3.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 OAG02833.1 - 0.99 10.1 13.0 11 6.7 1.2 3.4 2 2 0 2 2 2 0 SlyX DUF948 PF06103.11 OAG02833.1 - 1 9.7 3.7 1.8 8.9 0.2 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Myosin_tail_1 PF01576.19 OAG02833.1 - 2.4 5.8 25.1 0.79 7.4 15.6 2.2 2 1 0 2 2 2 0 Myosin tail Cluap1 PF10234.9 OAG02833.1 - 4.6 6.6 15.3 2.3 7.5 10.5 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF4795 PF16043.5 OAG02833.1 - 5.3 6.6 16.3 8.3 5.9 6.2 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) bZIP_1 PF00170.21 OAG02833.1 - 7.2 6.8 18.9 1.5 9.0 2.8 3.7 3 1 2 5 5 5 0 bZIP transcription factor SH3_1 PF00018.28 OAG02834.1 - 2.2e-05 23.9 0.0 5.5e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG02834.1 - 0.17 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain BCS1_N PF08740.11 OAG02835.1 - 4.6e-35 121.3 0.8 2.1e-34 119.1 0.6 2.0 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 OAG02835.1 - 2.5e-23 82.9 0.0 7.4e-23 81.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG02835.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAG02835.1 - 0.0027 18.1 0.0 0.0074 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 OAG02835.1 - 0.0027 17.7 0.0 0.055 13.5 0.0 2.9 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAG02835.1 - 0.0034 16.6 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAG02835.1 - 0.0057 17.2 0.0 0.014 16.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAG02835.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OAG02835.1 - 0.02 14.6 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAG02835.1 - 0.074 13.5 0.5 3.4 8.1 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 OAG02835.1 - 0.079 13.2 0.1 0.58 10.4 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 OAG02835.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG02835.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Tannase PF07519.11 OAG02836.1 - 2.6e-137 458.5 5.5 3.1e-137 458.3 5.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S10 PF00450.22 OAG02837.1 - 2.6e-100 336.8 8.2 3.2e-100 336.5 8.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Acyl-thio_N PF12590.8 OAG02837.1 - 0.042 14.4 0.1 1.4 9.5 0.0 2.7 1 1 2 3 3 3 0 Acyl-ATP thioesterase Ras PF00071.22 OAG02838.1 - 9.7e-57 191.1 0.1 1.2e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG02838.1 - 3e-32 111.4 0.0 4.3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG02838.1 - 1.5e-12 47.3 0.0 1.8e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG02838.1 - 1.1e-07 31.9 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG02838.1 - 1.2e-06 28.1 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAG02838.1 - 9.8e-06 25.2 0.0 0.00032 20.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG02838.1 - 3.3e-05 23.9 0.2 0.0046 16.9 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 OAG02838.1 - 0.00019 21.3 0.5 0.0042 16.9 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OAG02838.1 - 0.0019 18.0 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 OAG02838.1 - 0.0059 16.2 0.0 0.034 13.7 0.0 1.9 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OAG02838.1 - 0.0065 16.9 0.0 0.011 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OAG02838.1 - 0.0065 15.8 0.1 0.062 12.6 0.0 2.1 2 0 0 2 2 2 1 Septin SRPRB PF09439.10 OAG02838.1 - 0.0081 15.6 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OAG02838.1 - 0.0087 16.3 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG02838.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OAG02838.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG02838.1 - 0.026 14.0 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_hydro_75 PF07335.11 OAG02838.1 - 0.048 13.9 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 ATPase_2 PF01637.18 OAG02838.1 - 0.067 13.1 0.3 0.14 12.1 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 OAG02838.1 - 0.079 12.5 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 OAG02838.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 OAG02838.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 OAG02838.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase EamA PF00892.20 OAG02839.1 - 4.6e-11 43.0 28.4 8.4e-07 29.2 3.0 3.2 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 OAG02839.1 - 9.6e-06 25.3 0.2 9.6e-06 25.3 0.2 1.9 3 0 0 3 3 3 1 Solute carrier family 35 DUF3955 PF13127.6 OAG02839.1 - 3.7e-05 23.4 1.7 3.7e-05 23.4 1.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 OAG02839.1 - 0.0001 21.6 0.2 0.0001 21.6 0.2 2.9 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport CitMHS_2 PF16980.5 OAG02839.1 - 0.0056 15.4 1.1 0.3 9.7 0.0 2.2 2 0 0 2 2 2 2 Putative citrate transport UAA PF08449.11 OAG02839.1 - 0.0069 15.6 7.3 0.0077 15.5 6.1 1.7 2 1 0 2 2 2 1 UAA transporter family CRT-like PF08627.10 OAG02839.1 - 0.011 14.7 0.3 2 7.3 0.0 2.4 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like DUF3953 PF13129.6 OAG02839.1 - 3.5 7.5 7.8 1.9 8.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) TruB_N PF01509.18 OAG02840.1 - 2.6e-44 151.2 0.0 6.4e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAG02840.1 - 7.3e-07 29.3 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DnaJ PF00226.31 OAG02841.1 - 3.1e-18 65.6 0.1 8.3e-18 64.3 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain HA2 PF04408.23 OAG02843.1 - 2.5e-19 69.6 0.4 3.7e-18 65.8 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG02843.1 - 2.2e-16 60.0 0.0 4.4e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 OAG02843.1 - 1.8e-13 50.8 0.2 3.8e-13 49.7 0.2 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 OAG02843.1 - 3.4e-09 36.7 0.1 6.7e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.31 OAG02843.1 - 0.0007 19.4 0.5 0.08 12.9 0.0 2.7 2 0 0 2 2 2 1 UBA/TS-N domain Helicase_C PF00271.31 OAG02843.1 - 0.0011 19.3 0.0 0.0039 17.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAG02843.1 - 0.002 18.4 1.1 0.01 16.1 1.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG02843.1 - 0.011 15.5 0.0 0.056 13.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain HOIP-UBA PF16678.5 OAG02843.1 - 0.058 13.4 0.5 0.44 10.5 0.0 2.6 2 0 0 2 2 2 0 HOIP UBA domain pair T2SSE PF00437.20 OAG02843.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 OAG02843.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 OAG02843.1 - 0.086 12.2 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 OAG02843.1 - 0.095 13.2 0.0 0.38 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG02843.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain DND1_DSRM PF14709.7 OAG02843.1 - 0.37 11.1 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DcpS_C PF11969.8 OAG02844.1 - 5.3e-16 59.1 1.1 8.7e-08 32.6 0.7 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 OAG02844.1 - 2.4e-11 43.9 0.4 6e-11 42.6 0.4 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 OAG02844.1 - 3e-11 43.9 0.3 1.1e-10 42.1 0.3 1.9 1 1 0 1 1 1 1 HIT domain TRAP_alpha PF03896.16 OAG02845.1 - 2.1e-09 37.0 1.0 1.8e-08 33.9 1.0 2.0 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1616 PF07760.11 OAG02845.1 - 0.053 12.9 0.1 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) zf-CCCH_4 PF18044.1 OAG02846.1 - 0.17 11.7 19.7 0.27 11.1 2.4 3.9 3 0 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAG02846.1 - 0.67 10.1 20.8 0.24 11.5 0.6 4.0 4 0 0 4 4 4 0 Zinc finger domain Torus PF16131.5 OAG02846.1 - 7.4 7.3 6.8 1.1 10.0 0.1 2.5 2 1 1 3 3 3 0 Torus domain ETRAMP PF09716.10 OAG02847.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ac81 PF05820.11 OAG02847.1 - 5.2 6.6 5.1 8.4 5.9 5.1 1.3 1 0 0 1 1 1 0 Baculoviridae AC81 Methyltransf_25 PF13649.6 OAG02848.1 - 2.3e-09 37.9 0.0 7.6e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02848.1 - 3.6e-07 30.7 0.0 7.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02848.1 - 9.3e-06 26.3 0.0 1.9e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG02848.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG02848.1 - 0.02 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TILa PF12714.7 OAG02849.1 - 4.5 7.3 9.5 3.6 7.6 2.0 2.9 3 0 0 3 3 3 0 TILa domain FAD_binding_4 PF01565.23 OAG02850.1 - 1.8e-16 60.1 0.4 4.4e-16 58.9 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG02850.1 - 1.4e-12 47.5 0.1 6.7e-12 45.3 0.1 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 OAG02850.1 - 0.052 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding CMD PF02627.20 OAG02851.1 - 0.0032 17.5 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family zf-Mss51 PF13824.6 OAG02851.1 - 0.057 13.5 0.2 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 7TM_GPCR_Sra PF02117.16 OAG02852.1 - 0.13 11.1 0.7 0.17 10.7 0.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra DUF5337 PF17272.2 OAG02852.1 - 0.88 9.4 5.2 4.8 7.1 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5337) PIG-L PF02585.17 OAG02853.1 - 1.2e-24 87.4 0.0 1.7e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase F-box PF00646.33 OAG02854.1 - 0.0001 22.1 0.0 0.0003 20.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG02854.1 - 0.00051 19.9 0.4 0.0024 17.7 0.1 2.3 2 1 0 2 2 2 1 F-box-like DUF3280 PF11684.8 OAG02854.1 - 0.0079 16.6 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) F-box_4 PF15966.5 OAG02854.1 - 0.12 12.3 1.1 0.19 11.6 0.1 1.9 3 0 0 3 3 3 0 F-box SBP PF03110.14 OAG02854.1 - 0.59 10.5 5.5 0.38 11.1 0.5 2.6 2 1 1 3 3 3 0 SBP domain Spexin PF15171.6 OAG02855.1 - 0.053 13.7 0.1 4.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin EXOSC1 PF10447.9 OAG02856.1 - 2.7e-16 60.1 1.5 1.4e-11 45.0 0.4 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 OAG02856.1 - 3.6e-12 45.9 0.5 7.2e-12 44.9 0.5 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ras PF00071.22 OAG02857.1 - 2.6e-31 108.4 0.3 3.5e-31 108.0 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG02857.1 - 1.7e-23 83.1 0.1 3.1e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG02857.1 - 2.2e-06 27.3 0.1 2.9e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PT PF04886.12 OAG02857.1 - 1.9e-05 24.1 8.7 0.00054 19.4 0.6 3.5 3 0 0 3 3 3 2 PT repeat Gtr1_RagA PF04670.12 OAG02857.1 - 0.0001 21.8 0.3 0.00014 21.3 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 OAG02857.1 - 0.0019 17.1 0.2 1.1 8.0 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) CAF1C_H4-bd PF12265.8 OAG02858.1 - 5.2e-15 55.5 0.1 2.3e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAG02858.1 - 2e-13 50.6 6.6 3.5e-06 27.6 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG02858.1 - 8.9e-08 32.3 1.3 0.00038 20.7 0.1 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG02858.1 - 0.01 15.7 0.1 0.39 10.6 0.1 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OAG02858.1 - 0.04 11.9 0.1 0.08 10.9 0.1 1.5 1 1 0 1 1 1 0 IKI3 family Fungal_trans PF04082.18 OAG02860.1 - 1.1e-07 31.2 0.3 1.7e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like_2 PF13013.6 OAG02861.1 - 0.031 14.3 0.1 0.079 12.9 0.1 1.7 1 1 0 1 1 1 0 F-box-like domain DUF5463 PF17551.2 OAG02861.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5463) zf-RING_2 PF13639.6 OAG02863.1 - 8.9e-08 32.3 0.7 3.5e-07 30.5 0.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG02863.1 - 5.7e-05 22.8 0.5 0.00016 21.4 0.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OAG02863.1 - 0.00013 22.1 1.6 0.00013 22.1 1.6 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain RINGv PF12906.7 OAG02863.1 - 0.00034 20.7 0.5 0.00089 19.3 0.5 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_2 PF13923.6 OAG02863.1 - 0.00046 20.0 1.4 0.00046 20.0 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG02863.1 - 0.00065 19.7 1.6 0.0017 18.3 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAG02863.1 - 0.0033 17.4 0.4 0.0079 16.2 0.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG02863.1 - 0.016 15.1 0.8 0.016 15.1 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG02863.1 - 0.05 13.6 0.6 0.05 13.6 0.6 2.7 3 0 0 3 3 3 0 zinc-RING finger domain SDA1 PF05285.12 OAG02863.1 - 1.2 8.5 14.7 2.7 7.3 14.7 1.5 1 0 0 1 1 1 0 SDA1 Epimerase PF01370.21 OAG02864.1 - 2.3e-09 37.1 0.0 4.1e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG02864.1 - 4.4e-07 29.3 0.0 0.024 13.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 OAG02864.1 - 1.4e-05 25.0 0.0 2.7e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG02864.1 - 0.0094 15.5 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG02864.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DOT1 PF08123.13 OAG02865.1 - 1.9e-56 190.9 0.0 2.8e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 OAG02865.1 - 0.035 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.6 OAG02865.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ndc1_Nup PF09531.10 OAG02866.1 - 0.0018 17.1 3.1 0.0018 17.1 3.1 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup PARM PF17061.5 OAG02866.1 - 0.0048 17.1 11.5 0.0093 16.1 11.5 1.5 1 0 0 1 1 1 1 PARM TFIIA PF03153.13 OAG02866.1 - 0.07 13.1 11.6 0.083 12.9 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 OAG02866.1 - 0.19 11.6 8.9 0.25 11.2 8.9 1.3 1 0 0 1 1 1 0 SPX domain Nucleo_P87 PF07267.11 OAG02866.1 - 0.97 8.2 2.6 1.1 8.1 2.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 OAG02866.1 - 6 5.5 6.1 7.8 5.2 6.1 1.2 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 OAG02866.1 - 7.7 6.3 8.9 11 5.8 8.9 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RhoGAP PF00620.27 OAG02867.1 - 1.7e-37 128.6 0.0 2.7e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.15 OAG02868.1 - 4.3e-19 67.9 6.6 6.5e-19 67.3 6.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 OAG02868.1 - 0.00074 19.2 5.1 0.0015 18.2 5.1 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Ribosomal_S20p PF01649.18 OAG02868.1 - 0.054 14.1 0.1 0.067 13.8 0.1 1.3 1 1 0 1 1 1 0 Ribosomal protein S20 SCNM1_acidic PF15805.5 OAG02871.1 - 0.00079 19.1 0.4 0.0018 18.0 0.4 1.5 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 FrhB_FdhB_N PF04422.13 OAG02872.1 - 0.091 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Abhydrolase_6 PF12697.7 OAG02874.1 - 1.3e-07 32.4 0.6 1.8e-07 32.0 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG02874.1 - 2.5e-05 23.7 0.1 0.00018 20.9 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG02874.1 - 0.00016 21.4 0.2 0.00033 20.4 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold U1snRNP70_N PF12220.8 OAG02875.1 - 4e-27 94.7 1.9 7.1e-27 93.9 1.9 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 OAG02875.1 - 1.8e-16 59.7 0.0 3.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG02875.1 - 0.0022 18.1 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 OAG02876.1 - 4.6e-11 42.5 0.1 7.5e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 OAG02877.1 - 4.9e-87 291.3 0.3 5.5e-87 291.2 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase GST_N_4 PF17172.4 OAG02878.1 - 3.7e-18 66.1 0.1 9.4e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OAG02878.1 - 2.1e-14 53.1 0.0 3.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OAG02878.1 - 6e-10 39.5 0.1 1e-09 38.8 0.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 OAG02878.1 - 2.3e-06 27.5 0.2 5.4e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 OAG02878.1 - 3.9e-06 27.1 0.0 7.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex Methyltransf_31 PF13847.6 OAG02879.1 - 5.4e-12 45.8 0.0 5.5e-11 42.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG02879.1 - 2.6e-11 44.1 0.0 1.7e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG02879.1 - 9.4e-11 42.3 0.0 6.5e-10 39.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG02879.1 - 2.1e-10 40.7 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG02879.1 - 2.2e-10 41.1 0.0 9.7e-10 39.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG02879.1 - 7.4e-05 22.2 0.0 0.00017 21.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG02879.1 - 0.0043 16.6 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 OAG02879.1 - 0.036 13.5 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB ADH_zinc_N PF00107.26 OAG02879.1 - 0.037 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_7 PF03492.15 OAG02879.1 - 0.045 13.0 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Methyltransf_33 PF10017.9 OAG02879.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent IF4E PF01652.18 OAG02880.1 - 2.2e-33 115.3 0.6 2.9e-33 114.9 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.6 OAG02881.1 - 3e-23 82.4 1.5 3e-23 82.4 1.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) DDHD PF02862.17 OAG02881.1 - 0.0058 16.8 1.6 0.01 16.1 1.6 1.3 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 OAG02881.1 - 1.4 7.6 3.0 1.7 7.3 3.0 1.2 1 0 0 1 1 1 0 Presenilin DUF1264 PF06884.11 OAG02882.1 - 1.7e-74 249.1 0.1 2e-74 248.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) zf-C2H2_aberr PF17017.5 OAG02883.1 - 4.3e-05 23.7 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2 PF00096.26 OAG02883.1 - 0.0023 18.3 11.1 0.22 12.0 0.1 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG02883.1 - 0.051 14.4 11.3 2.2 9.3 2.4 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger GFA PF04828.14 OAG02884.1 - 4.5e-16 59.0 0.6 4.5e-16 59.0 0.6 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme OrfA PF17495.2 OAG02884.1 - 0.098 12.8 1.8 0.15 12.2 1.8 1.2 1 0 0 1 1 1 0 Vpr-like OrfA Band_7 PF01145.25 OAG02885.1 - 6.9e-25 88.1 9.8 9.2e-25 87.7 8.8 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 OAG02885.1 - 9.4e-05 21.6 3.5 0.00013 21.2 3.5 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF1908 PF08926.11 OAG02886.1 - 0.11 11.6 0.3 0.2 10.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) HAD_2 PF13419.6 OAG02887.1 - 6.9e-09 36.0 0.0 1.5e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG02887.1 - 0.0015 18.9 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UQ_con PF00179.26 OAG02888.1 - 2.8e-39 133.9 0.0 3.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG02888.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 OAG02888.1 - 0.032 13.9 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RNase_PH PF01138.21 OAG02889.1 - 2.9e-11 44.0 0.0 4.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ABC_cobalt PF09819.9 OAG02890.1 - 0.058 13.5 0.1 0.058 13.5 0.1 1.7 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component A_deaminase PF00962.22 OAG02891.1 - 2.5e-23 83.0 0.0 1.9e-20 73.5 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF3347 PF11827.8 OAG02891.1 - 0.017 15.3 1.2 0.042 14.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) XAP5 PF04921.14 OAG02891.1 - 0.059 13.2 1.2 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 XAP5, circadian clock regulator LIM PF00412.22 OAG02893.1 - 1.1e-18 67.1 20.8 1.3e-10 41.3 2.9 2.7 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 OAG02893.1 - 0.046 13.4 0.7 7 6.4 0.1 2.6 2 0 0 2 2 2 0 WRC NAD_binding_5 PF07994.12 OAG02895.1 - 4e-143 476.6 0.0 4.6e-143 476.4 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OAG02895.1 - 9.5e-45 151.3 0.9 2.1e-44 150.2 0.4 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Rep_fac-A_C PF08646.10 OAG02896.1 - 0.02 14.7 0.2 0.084 12.6 0.1 1.9 2 0 0 2 2 2 0 Replication factor-A C terminal domain MIS13 PF08202.11 OAG02897.1 - 9.1e-51 172.9 0.0 2.2e-50 171.7 0.0 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Laminin_I PF06008.14 OAG02897.1 - 0.047 13.4 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 Laminin Domain I ABC_tran_CTD PF16326.5 OAG02897.1 - 0.36 11.1 6.5 0.11 12.7 2.5 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain PS_Dcarbxylase PF02666.15 OAG02898.1 - 1.5e-55 187.9 0.0 2.2e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OAG02898.1 - 6.6e-38 129.1 0.1 1.3e-18 67.2 0.1 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 OAG02898.1 - 0.0035 17.8 0.4 0.012 16.1 0.4 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG02898.1 - 0.039 13.5 0.3 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 OAG02898.1 - 0.042 13.8 0.6 0.32 11.0 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain CDC45 PF02724.14 OAG02898.1 - 0.62 8.3 5.6 0.95 7.7 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Di19_C PF14571.6 OAG02898.1 - 0.82 10.2 4.4 3 8.4 4.4 1.9 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal U3_snoRNA_assoc PF08297.11 OAG02898.1 - 2.9 8.6 7.7 14 6.5 7.7 2.2 1 0 0 1 1 1 0 U3 snoRNA associated Pet191_N PF10203.9 OAG02899.1 - 0.0069 16.7 2.8 0.0083 16.4 2.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NmrA PF05368.13 OAG02900.1 - 1.2e-52 178.9 0.0 1.4e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG02900.1 - 5.1e-16 59.1 0.0 9.2e-16 58.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG02900.1 - 1.4e-06 27.6 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG02900.1 - 6.3e-06 25.8 0.0 8.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG02900.1 - 0.0019 18.4 0.0 0.0038 17.5 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Transketolase_N PF00456.21 OAG02901.1 - 9.9e-154 511.2 0.3 1.3e-153 510.9 0.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG02901.1 - 3.4e-45 153.9 0.0 5.7e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG02901.1 - 3.9e-15 55.8 0.0 9.6e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG02901.1 - 0.00029 20.1 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase GtrA PF04138.14 OAG02901.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 GtrA-like protein Beta_elim_lyase PF01212.21 OAG02901.1 - 0.042 13.1 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase E1_dh PF00676.20 OAG02901.1 - 0.06 12.3 0.2 0.099 11.6 0.2 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component CFEM PF05730.11 OAG02902.1 - 0.0003 20.8 5.4 0.00054 20.0 5.4 1.4 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 OAG02902.1 - 1.2 8.5 2.9 2.9 7.4 2.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain G-alpha PF00503.20 OAG02904.1 - 2.9e-121 405.0 2.3 3.4e-121 404.7 2.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG02904.1 - 4.7e-15 55.5 2.5 2.4e-10 40.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 OAG02904.1 - 0.0004 20.1 0.0 0.0018 18.1 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 OAG02904.1 - 0.003 17.0 4.4 0.061 12.7 0.1 2.7 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 OAG02904.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 OAG02904.1 - 0.02 15.1 0.2 2.4 8.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OAG02904.1 - 0.081 12.5 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 OAG02904.1 - 0.083 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain MMR_HSR1 PF01926.23 OAG02904.1 - 0.13 12.3 0.1 8.4 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OAG02904.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Utp12 PF04003.12 OAG02905.1 - 0.0098 16.2 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Aminotran_1_2 PF00155.21 OAG02907.1 - 1.1e-58 199.1 0.0 4.9e-58 197.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II KR PF08659.10 OAG02907.1 - 2.8e-35 121.9 0.1 4.6e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Beta_elim_lyase PF01212.21 OAG02907.1 - 0.00031 20.1 0.1 0.0006 19.2 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase p450 PF00067.22 OAG02909.1 - 3.9e-51 174.2 0.0 5.4e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.13 OAG02911.1 - 8.7e-10 38.6 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Homeodomain PF00046.29 OAG02912.1 - 1.2e-19 69.9 5.1 2.3e-19 69.0 5.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG02912.1 - 0.00039 20.3 0.9 0.001 18.9 0.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 OAG02912.1 - 0.15 11.9 0.5 0.66 9.9 0.3 1.9 2 0 0 2 2 2 0 Homeodomain-like domain MDM10 PF12519.8 OAG02914.1 - 6.3e-154 513.3 2.1 6e-135 450.7 0.9 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 OAG02914.1 - 4.7e-07 29.6 0.0 0.029 13.8 0.0 2.8 3 1 0 3 3 3 2 Eukaryotic porin RL10P_insert PF17777.1 OAG02915.1 - 2.1e-25 88.5 0.0 4e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OAG02915.1 - 6.9e-21 74.3 0.1 1.2e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 FAD_binding_3 PF01494.19 OAG02918.1 - 3.9e-10 39.5 0.0 2e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG02918.1 - 1.1e-07 31.4 0.6 7.2e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG02918.1 - 4.8e-07 29.2 0.1 8.7e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG02918.1 - 1.4e-05 25.2 0.2 3.7e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG02918.1 - 0.00018 20.3 0.2 0.0014 17.5 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OAG02918.1 - 0.0003 20.5 3.4 0.019 14.6 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG02918.1 - 0.00074 19.0 0.1 0.0015 17.9 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG02918.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG02918.1 - 0.022 14.0 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG02918.1 - 0.026 13.8 0.3 0.068 12.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 OAG02918.1 - 0.03 13.6 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAG02918.1 - 0.094 13.3 0.9 0.68 10.5 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 OAG02919.1 - 1.8e-83 280.8 0.0 2.1e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.8 OAG02921.1 - 5.4e-17 61.9 0.0 1.3e-16 60.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG02921.1 - 0.004 17.2 1.9 0.0077 16.3 1.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor CENP-F_leu_zip PF10473.9 OAG02921.1 - 0.097 12.7 1.2 0.14 12.1 1.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SVIP PF15811.5 OAG02921.1 - 0.13 12.7 2.0 0.26 11.8 2.0 1.4 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Abhydrolase_3 PF07859.13 OAG02922.1 - 3.2e-24 86.0 0.0 4.4e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG02922.1 - 1.4e-21 76.8 0.0 2e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Pex14_N PF04695.13 OAG02923.1 - 0.00069 20.3 1.1 0.00087 20.0 1.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Orf78 PF06024.12 OAG02923.1 - 0.11 12.8 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Tyr-DNA_phospho PF06087.12 OAG02924.1 - 0.092 11.6 3.8 0.11 11.3 3.8 1.2 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase alpha-hel2 PF14456.6 OAG02925.1 - 0.018 14.3 0.3 0.025 13.9 0.3 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 STAG PF08514.11 OAG02926.1 - 5.3e-32 110.1 0.3 5.3e-32 110.1 0.3 3.5 3 0 0 3 3 3 1 STAG domain Cnd3 PF12719.7 OAG02926.1 - 0.015 14.5 0.0 1.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 OAG02926.1 - 0.04 14.2 1.4 49 4.6 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat Epimerase PF01370.21 OAG02928.1 - 7.6e-16 58.3 0.1 2e-15 56.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG02928.1 - 2.9e-15 56.0 0.0 7.3e-15 54.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG02928.1 - 3.1e-14 53.3 0.7 1.7e-13 50.9 0.3 2.0 1 1 1 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAG02928.1 - 8.4e-13 48.1 0.1 2.7e-06 26.8 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.13 OAG02928.1 - 9.5e-10 38.4 0.2 1.6e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG02928.1 - 6.1e-09 35.7 0.6 5.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG02928.1 - 2.4e-06 27.6 0.4 5.4e-06 26.4 0.4 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG02928.1 - 1.2e-05 24.6 0.1 1.7e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAG02928.1 - 9.7e-05 21.9 0.1 0.00031 20.2 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 OAG02928.1 - 0.0075 15.4 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 OAG02928.1 - 0.01 16.1 0.1 0.036 14.3 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SpoU_sub_bind PF08032.12 OAG02928.1 - 0.13 12.5 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Cullin PF00888.22 OAG02929.1 - 1.5e-179 598.6 6.1 1.8e-179 598.3 6.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG02929.1 - 1.2e-21 76.4 0.3 3.4e-21 75.0 0.3 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain POT1PC PF16686.5 OAG02930.1 - 3.1e-36 124.6 0.0 4.9e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 OAG02930.1 - 0.0068 16.2 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.23 OAG02931.1 - 1.7e-97 316.9 12.8 8.9e-14 51.0 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 OAG02931.1 - 3e-27 94.9 1.6 7.6e-27 93.6 1.6 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 OAG02931.1 - 2.8e-23 81.2 2.1 7.1e-23 79.9 2.1 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 OAG02931.1 - 3.1e-22 78.6 5.0 1.8e-08 34.7 0.1 6.6 7 0 0 7 7 6 5 HEAT-like repeat HEAT_2 PF13646.6 OAG02931.1 - 2.2e-20 72.8 0.3 5.1e-09 36.4 0.0 5.6 1 1 5 6 6 6 3 HEAT repeats HEAT PF02985.22 OAG02931.1 - 8.8e-18 62.9 1.9 1.8e-05 24.6 0.0 7.3 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.13 OAG02931.1 - 2.4e-08 33.8 0.0 0.063 12.7 0.0 4.1 2 1 2 4 4 4 4 Armadillo-like V-ATPase_H_C PF11698.8 OAG02931.1 - 6.6e-06 26.2 0.0 1.3 9.1 0.0 4.8 2 1 4 6 6 6 2 V-ATPase subunit H Adaptin_N PF01602.20 OAG02931.1 - 1.1e-05 24.2 0.0 0.00038 19.2 0.0 2.6 1 1 1 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 OAG02931.1 - 0.00082 19.5 0.0 0.97 9.5 0.0 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 OAG02931.1 - 0.0039 16.8 0.0 4.6 6.8 0.0 3.4 1 1 1 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 HEAT_PBS PF03130.16 OAG02931.1 - 0.018 15.7 4.9 0.85 10.5 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 OAG02931.1 - 0.02 15.1 5.9 5.9 7.2 0.2 4.9 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 OAG02931.1 - 0.045 13.6 0.0 33 4.4 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain GATase_4 PF13230.6 OAG02932.1 - 1.2e-16 60.4 0.0 6e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 OAG02932.1 - 9.6e-10 38.8 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain PUL PF08324.11 OAG02935.1 - 4.2e-47 160.7 0.2 6.2e-47 160.1 0.2 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 OAG02935.1 - 9.9e-40 135.8 0.0 1.6e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 OAG02935.1 - 6e-11 42.3 0.0 1.6e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 OAG02935.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 OAG02935.1 - 0.025 15.0 0.3 1.6 9.2 0.3 3.4 3 1 0 3 3 3 0 Thioredoxin-like domain Ins_P5_2-kin PF06090.12 OAG02937.1 - 4.3e-48 164.5 0.0 5.3e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase WD40 PF00400.32 OAG02938.1 - 9e-16 58.0 3.7 0.31 12.0 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG02938.1 - 0.013 15.8 0.0 15 5.9 0.0 3.5 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 OAG02938.1 - 0.36 9.0 10.9 0.59 8.3 10.9 1.3 1 0 0 1 1 1 0 Nop14-like family AAA_12 PF13087.6 OAG02939.1 - 3.7e-39 134.4 0.0 5.7e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG02939.1 - 4.6e-22 79.1 0.2 2.7e-21 76.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG02939.1 - 1.1e-07 32.2 0.0 1.1e-06 29.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG02939.1 - 2.7e-07 30.5 0.0 2.3e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OAG02939.1 - 8.7e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 OAG02939.1 - 9.6e-05 22.2 0.0 0.12 12.1 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAG02939.1 - 0.00013 22.0 0.1 0.00024 21.1 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG02939.1 - 0.0012 18.7 0.8 0.005 16.6 0.1 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF2075 PF09848.9 OAG02939.1 - 0.0028 17.0 0.0 0.074 12.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 OAG02939.1 - 0.05 13.1 0.1 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 OAG02939.1 - 0.053 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAG02939.1 - 0.054 13.8 0.3 1.3 9.3 0.0 3.0 2 1 1 3 3 3 0 AAA domain RuvB_N PF05496.12 OAG02939.1 - 0.17 11.7 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain HCV_NS4b PF01001.19 OAG02940.1 - 0.069 12.7 0.3 0.17 11.4 0.3 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b FAM199X PF15814.5 OAG02940.1 - 1.9 7.5 10.2 3.1 6.8 10.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X Thiamine_BP PF01910.17 OAG02941.1 - 4.9e-33 112.9 0.1 5.8e-33 112.7 0.1 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Retro_M PF02813.14 OAG02941.1 - 0.079 13.3 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral M domain Peptidase_M14 PF00246.24 OAG02942.1 - 4.7e-79 266.2 1.7 5.7e-79 265.9 1.7 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OAG02942.1 - 0.0073 16.7 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Zn_clus PF00172.18 OAG02943.1 - 4.3e-06 26.7 8.1 7.2e-06 26.0 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG02943.1 - 5.2e-06 25.7 0.3 6.2e-05 22.2 0.3 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2272 PF10030.9 OAG02944.1 - 0.0026 17.5 0.2 0.0033 17.2 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2272) Abhydrolase_3 PF07859.13 OAG02946.1 - 2.6e-46 158.2 0.0 3.8e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG02946.1 - 5.6e-06 25.5 0.1 1.3e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 OAG02946.1 - 0.0017 19.0 0.2 0.0028 18.3 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAG02946.1 - 0.2 11.2 0.0 0.77 9.3 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 OAG02946.1 - 0.45 10.0 1.9 16 4.9 1.9 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase adh_short PF00106.25 OAG02947.1 - 5.9e-42 143.4 0.0 7e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02947.1 - 1.8e-38 132.4 0.1 2.1e-38 132.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG02947.1 - 1.1e-08 35.3 0.0 2.2e-08 34.2 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG02947.1 - 0.0022 17.5 0.3 0.0089 15.5 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG02947.1 - 0.0037 16.7 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG02947.1 - 0.019 14.1 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LDcluster4 PF18306.1 OAG02947.1 - 0.057 13.0 2.8 0.099 12.2 0.1 2.4 2 1 0 2 2 2 0 SLOG cluster4 family 2-Hacid_dh_C PF02826.19 OAG02947.1 - 0.069 12.5 0.2 0.12 11.7 0.2 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OAG02947.1 - 0.17 11.8 0.1 7 6.5 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H-binding FAD_binding_6 PF00970.24 OAG02948.1 - 7.8e-33 112.8 0.0 1.2e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG02948.1 - 5.9e-27 94.5 0.0 9.3e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG02948.1 - 4e-05 23.8 0.0 0.009 16.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAG02948.1 - 0.091 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Pkinase PF00069.25 OAG02949.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.11 OAG02949.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 OAG02949.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Mannosidase_ig PF17786.1 OAG02950.1 - 0.078 13.6 0.9 0.79 10.4 1.0 2.2 2 0 0 2 2 2 0 Mannosidase Ig/CBM-like domain zf-C3H1 PF10650.9 OAG02951.1 - 0.0002 21.0 5.0 0.00032 20.3 5.0 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Rootletin PF15035.6 OAG02951.1 - 7.5 6.5 17.6 5.3 7.0 14.9 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF5472 PF17566.2 OAG02953.1 - 0.051 13.5 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5472) DUF4211 PF13926.6 OAG02954.1 - 3.8e-42 143.7 0.3 3e-41 140.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Acetyltransf_10 PF13673.7 OAG02955.1 - 9e-10 38.6 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG02955.1 - 1.5e-06 28.5 0.0 2.2e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG02955.1 - 3.6e-05 24.1 0.0 7.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG02955.1 - 0.0018 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG02955.1 - 0.0054 16.7 0.0 0.014 15.4 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein MOZ_SAS PF01853.18 OAG02955.1 - 0.045 13.4 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family DLH PF01738.18 OAG02956.1 - 4.8e-17 62.2 0.0 3.4e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 OAG02956.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Taeniidae_ag PF05596.11 OAG02956.1 - 0.18 11.8 0.0 0.55 10.3 0.0 1.8 1 0 0 1 1 1 0 Taeniidae antigen Fungal_trans PF04082.18 OAG02957.1 - 4e-10 39.2 0.0 6.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG02957.1 - 4.7e-08 33.0 11.1 1.1e-07 31.8 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mu-like_Pro PF10123.9 OAG02957.1 - 0.053 13.1 0.1 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 Mu-like prophage I protein Ribosomal_S14 PF00253.21 OAG02958.1 - 6.5e-15 54.6 2.4 7e-15 54.5 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Pol_alpha_B_N PF08418.10 OAG02959.1 - 1.5e-72 244.5 1.0 2.1e-72 244.1 1.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 OAG02959.1 - 6.3e-34 117.2 0.0 1.8e-33 115.7 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B MRNIP PF15749.5 OAG02959.1 - 0.015 16.0 0.1 0.028 15.2 0.1 1.4 1 0 0 1 1 1 0 MRN-interacting protein CRAL_TRIO PF00650.20 OAG02960.1 - 1e-37 129.3 0.0 1.3e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG02960.1 - 3.2e-16 59.2 0.9 5.8e-16 58.4 0.9 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG02960.1 - 4.7e-08 33.3 0.0 6.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Zn_clus PF00172.18 OAG02962.1 - 1.2e-07 31.8 9.7 1.2e-07 31.8 9.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG02962.1 - 0.00037 19.4 0.0 0.00049 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF679 PF05078.12 OAG02962.1 - 0.067 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF679) adh_short PF00106.25 OAG02963.1 - 6.4e-39 133.4 0.0 1.2e-38 132.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG02963.1 - 2.2e-23 83.1 0.1 6e-23 81.6 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG02963.1 - 4.4e-09 36.5 0.3 7.1e-09 35.8 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG02963.1 - 1.3e-07 31.7 0.1 2.6e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG02963.1 - 0.00014 22.1 0.1 0.00026 21.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG02963.1 - 0.00028 20.4 0.2 0.00054 19.5 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG02963.1 - 0.0021 17.5 0.2 0.0028 17.1 0.2 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.15 OAG02963.1 - 0.006 16.8 0.0 0.024 14.8 0.0 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OAG02963.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAG02963.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 OAG02963.1 - 0.15 11.4 0.3 1.7 7.9 0.0 2.5 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase RCC1 PF00415.18 OAG02964.1 - 2.8e-08 34.2 0.6 0.00043 20.8 0.0 4.4 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG02964.1 - 1.2e-07 31.3 25.1 0.0001 22.0 0.5 6.6 8 0 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 OAG02964.1 - 0.001 18.9 0.3 0.002 18.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG02964.1 - 0.012 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain IF-2B PF01008.17 OAG02965.1 - 1.6e-72 244.1 0.0 2.1e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Med13_C PF06333.12 OAG02965.1 - 0.048 12.9 1.1 0.084 12.1 1.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain CheC PF04509.12 OAG02965.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 CheC-like family Ndc1_Nup PF09531.10 OAG02965.1 - 0.36 9.5 4.0 0.48 9.0 4.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3402 PF11882.8 OAG02965.1 - 0.57 9.2 4.0 0.87 8.6 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Senescence_reg PF04520.13 OAG02965.1 - 2.7 8.8 10.6 99 3.7 9.7 2.2 2 0 0 2 2 2 0 Senescence regulator Presenilin PF01080.17 OAG02965.1 - 4 6.1 6.4 6 5.5 6.4 1.2 1 0 0 1 1 1 0 Presenilin TadE PF07811.12 OAG02967.1 - 0.24 11.7 0.7 0.48 10.7 0.7 1.4 1 0 0 1 1 1 0 TadE-like protein PI3K_P85_iSH2 PF16454.5 OAG02968.1 - 0.0002 21.0 4.3 0.0002 21.0 4.3 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain LRRFIP PF09738.9 OAG02968.1 - 0.0015 18.1 12.0 0.0015 18.1 12.0 2.8 1 1 2 3 3 3 2 LRRFIP family bZIP_1 PF00170.21 OAG02968.1 - 0.17 12.0 14.9 4.9 7.3 0.4 4.1 3 2 0 3 3 3 0 bZIP transcription factor DUF1942 PF09167.11 OAG02968.1 - 0.21 11.6 1.2 0.44 10.5 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) APG6_N PF17675.1 OAG02968.1 - 0.82 10.2 42.9 0.41 11.2 14.4 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region AAA_13 PF13166.6 OAG02968.1 - 0.89 8.1 22.9 1.6 7.3 22.9 1.3 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 OAG02968.1 - 2.9 8.4 29.0 11 6.6 3.2 4.9 2 1 1 4 4 4 0 Cell division protein ZapB Macoilin PF09726.9 OAG02968.1 - 3.1 6.2 20.8 5.4 5.4 20.8 1.4 1 0 0 1 1 1 0 Macoilin family DUF1640 PF07798.11 OAG02968.1 - 4.6 7.3 27.4 0.17 11.9 5.6 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) GAS PF13851.6 OAG02968.1 - 5.3 6.3 34.2 1.6 8.0 16.8 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 OAG02968.1 - 6.9 6.2 35.4 15 5.0 34.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 OAG02968.1 - 9.7 5.0 36.0 6.8 5.5 26.9 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein Phosducin PF02114.16 OAG02971.1 - 5.9e-09 35.3 0.1 1.6e-06 27.3 0.1 2.2 1 1 1 2 2 2 2 Phosducin MreC PF04085.14 OAG02971.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 rod shape-determining protein MreC DUF3928 PF13065.6 OAG02971.1 - 0.073 13.8 0.1 0.15 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) SpoVAE PF14097.6 OAG02971.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AE1 EF-1_beta_acid PF10587.9 OAG02971.1 - 0.13 12.7 0.7 0.13 12.7 0.7 2.6 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Sugar_tr PF00083.24 OAG02973.1 - 1.7e-119 399.7 34.9 1.9e-119 399.5 34.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG02973.1 - 2.2e-27 95.9 41.1 2.2e-27 95.9 41.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG02973.1 - 0.52 8.8 31.2 0.69 8.4 9.8 3.2 2 1 1 3 3 3 0 MFS/sugar transport protein YrhK PF14145.6 OAG02973.1 - 0.66 9.9 0.0 0.66 9.9 0.0 3.8 3 0 0 3 3 3 0 YrhK-like protein Internalin_N PF12354.8 OAG02974.1 - 0.14 12.2 0.8 0.26 11.4 0.8 1.3 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal WD40 PF00400.32 OAG02975.1 - 2.2e-38 129.6 20.1 1.5e-05 25.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG02975.1 - 1.2e-16 60.8 0.0 0.00025 21.3 0.1 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG02975.1 - 7.1e-05 22.8 0.0 0.038 13.9 0.0 2.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG02975.1 - 0.0015 18.0 0.0 0.034 13.5 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 OAG02975.1 - 0.14 10.7 0.0 0.27 9.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain A_deaminase PF00962.22 OAG02976.1 - 1.1e-29 103.8 0.0 1.3e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF4360 PF14273.6 OAG02978.1 - 4e-61 206.0 6.3 4.7e-61 205.8 6.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Velvet PF11754.8 OAG02979.1 - 0.00017 21.6 0.0 0.00025 21.1 0.0 1.5 1 1 0 1 1 1 1 Velvet factor tRNA-synt_1d PF00750.19 OAG02980.1 - 5.2e-102 341.3 9.8 5e-101 338.1 9.8 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAG02980.1 - 3.3e-28 98.2 0.2 3.3e-28 98.2 0.2 3.0 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OAG02980.1 - 5.6e-05 23.6 0.0 0.00018 22.0 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain LMBR1 PF04791.16 OAG02980.1 - 0.041 12.8 0.9 0.068 12.1 0.5 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF3288 PF11691.8 OAG02980.1 - 0.095 12.8 0.0 0.52 10.4 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) POT1 PF02765.17 OAG02980.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 DUF148 PF02520.17 OAG02980.1 - 0.18 11.9 5.7 0.22 11.6 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF148 SAWADEE PF16719.5 OAG02980.1 - 0.29 11.1 1.8 0.56 10.2 0.0 2.2 3 0 0 3 3 3 0 SAWADEE domain DivIC PF04977.15 OAG02980.1 - 1.3 8.8 6.3 7.8 6.4 3.2 2.6 2 0 0 2 2 2 0 Septum formation initiator COMPASS-Shg1 PF05205.12 OAG02981.1 - 3.8e-20 72.5 0.0 3.8e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 UPF0052 PF01933.18 OAG02983.1 - 2.7e-66 223.8 0.0 3.5e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 GST_N_3 PF13417.6 OAG02984.1 - 4.5e-10 39.8 0.0 7.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG02984.1 - 1.5e-06 28.1 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG02984.1 - 8.4e-05 22.7 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG02984.1 - 0.0021 18.3 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain IMS PF00817.20 OAG02987.1 - 1.2e-40 138.9 0.0 2.5e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 OAG02987.1 - 3.6e-14 52.1 0.5 8.6e-14 50.8 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 OAG02987.1 - 1.8e-11 44.8 0.1 1.3e-10 42.0 0.0 2.4 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain Pinin_SDK_N PF04697.13 OAG02987.1 - 0.072 13.7 1.4 0.18 12.4 1.4 1.6 1 0 0 1 1 1 0 pinin/SDK conserved region IMS_HHH PF11798.8 OAG02987.1 - 0.075 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 IMS family HHH motif WD40 PF00400.32 OAG02988.1 - 0.013 16.3 6.5 2.3 9.2 0.0 4.4 3 1 0 3 3 3 0 WD domain, G-beta repeat F-box-like_2 PF13013.6 OAG02989.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain PBP1_TM PF14812.6 OAG02989.1 - 0.21 12.0 3.1 0.44 10.9 3.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal polyprenyl_synt PF00348.17 OAG02990.1 - 1.4e-63 214.3 0.0 1.7e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Dynamin_N PF00350.23 OAG02991.1 - 6e-44 150.1 0.0 1.1e-43 149.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAG02991.1 - 2e-10 40.4 0.0 4.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 OAG02991.1 - 7.7e-05 22.7 0.0 0.00021 21.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG02991.1 - 0.057 13.8 1.1 0.21 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 OAG02991.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG02991.1 - 0.096 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain UreD PF01774.17 OAG02992.1 - 1.1e-76 257.5 0.0 1.3e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein SelB-wing_1 PF09105.10 OAG02992.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix B-block_TFIIIC PF04182.12 OAG02993.1 - 1.4e-15 57.2 0.0 3.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.22 OAG02993.1 - 0.00038 20.3 0.0 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 1 MarR family V-ATPase_G_2 PF16999.5 OAG02993.1 - 0.025 15.0 11.8 0.077 13.4 11.8 1.9 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF5457 PF17540.2 OAG02993.1 - 0.046 13.8 0.5 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5457) AT_hook PF02178.19 OAG02993.1 - 7.9 6.7 22.0 5.9 7.1 2.4 4.4 3 0 0 3 3 3 0 AT hook motif Glyco_hydro_61 PF03443.14 OAG02994.1 - 1e-43 149.7 0.4 1.2e-43 149.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_64 PF16483.5 OAG02997.1 - 1.7e-135 452.1 0.3 2e-135 451.8 0.3 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Bacteriocin_II PF01721.18 OAG03001.1 - 0.14 12.3 0.1 0.41 10.8 0.1 1.8 1 0 0 1 1 1 0 Class II bacteriocin Suf PF05843.14 OAG03002.1 - 0.36 10.8 1.6 0.36 10.8 1.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cation_efflux PF01545.21 OAG03003.1 - 2.3e-49 167.8 11.6 3.2e-49 167.4 11.6 1.2 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 OAG03003.1 - 0.017 14.3 0.3 0.017 14.3 0.3 2.4 2 1 1 3 3 3 0 Branched-chain amino acid transport system / permease component PAP2_3 PF14378.6 OAG03003.1 - 0.032 13.9 2.3 4.2 7.0 0.5 2.4 2 0 0 2 2 2 0 PAP2 superfamily zf-met2 PF12907.7 OAG03004.1 - 5.6e-14 52.0 7.3 1.1e-13 51.0 7.3 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 OAG03004.1 - 0.0005 20.9 9.2 0.001 19.9 9.2 1.5 1 0 0 1 1 1 1 4F5 protein family RIG-I_C PF18119.1 OAG03005.1 - 0.72 9.9 4.2 4.7 7.2 0.0 3.3 3 0 0 3 3 3 0 RIG-I receptor C-terminal domain AAA PF00004.29 OAG03006.1 - 4.9e-20 72.3 0.0 8.6e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG03006.1 - 0.0013 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG03006.1 - 0.0019 18.6 1.5 0.0044 17.4 0.2 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG03006.1 - 0.0027 18.0 0.2 0.035 14.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG03006.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG03006.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DCP1 PF06058.13 OAG03006.1 - 0.045 13.7 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Dcp1-like decapping family AAA_33 PF13671.6 OAG03006.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAG03006.1 - 0.1 12.7 0.0 0.31 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 OAG03006.1 - 0.19 11.1 0.3 0.35 10.2 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OAG03007.1 - 5.1e-08 33.0 0.0 1.8e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG03007.1 - 2e-06 28.3 0.1 1.3e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG03007.1 - 2.5e-05 24.6 0.0 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG03007.1 - 0.0016 18.4 0.1 0.009 15.9 0.0 2.2 3 0 0 3 3 3 1 RsgA GTPase AAA_18 PF13238.6 OAG03007.1 - 0.007 16.9 0.1 0.052 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG03007.1 - 0.008 16.7 0.0 0.029 14.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Ploopntkinase1 PF18748.1 OAG03007.1 - 0.02 14.4 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 SesA PF17107.5 OAG03007.1 - 0.028 14.6 0.1 0.09 13.0 0.1 2.0 2 0 0 2 2 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases dNK PF01712.19 OAG03007.1 - 0.028 14.3 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_29 PF13555.6 OAG03007.1 - 0.033 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 OAG03007.1 - 0.038 13.2 2.9 0.22 10.6 0.2 2.5 1 1 2 3 3 3 0 G-protein alpha subunit RNA_helicase PF00910.22 OAG03007.1 - 0.039 14.3 0.0 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF1848 PF08902.11 OAG03007.1 - 0.089 12.5 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Spo0A_C PF08769.11 OAG03007.1 - 0.14 12.2 0.3 0.35 11.0 0.3 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal AAA_23 PF13476.6 OAG03007.1 - 1.8 9.0 0.0 1.8 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain GST_N_2 PF13409.6 OAG03008.1 - 6.5e-15 55.2 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG03008.1 - 1.2e-09 38.0 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG03008.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG03008.1 - 0.053 13.9 0.0 9.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Tim17 PF02466.19 OAG03011.1 - 1.1e-31 109.4 8.6 1.6e-31 109.0 8.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 OAG03011.1 - 0.012 15.7 0.9 0.012 15.7 0.9 2.3 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III BTB PF00651.31 OAG03012.1 - 0.04 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain DDOST_48kD PF03345.14 OAG03014.1 - 9.7e-154 512.2 0.0 1.1e-153 511.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta MARVEL PF01284.23 OAG03016.1 - 0.035 14.1 2.0 0.07 13.2 1.6 1.9 1 1 0 1 1 1 0 Membrane-associating domain Tetraspanin PF00335.20 OAG03016.1 - 0.47 10.1 3.9 0.41 10.3 2.5 1.7 1 1 0 1 1 1 0 Tetraspanin family SUR7 PF06687.12 OAG03016.1 - 3.7 7.1 8.6 1.9 8.0 4.2 2.4 2 1 0 2 2 2 0 SUR7/PalI family Acyltransferase PF01553.21 OAG03017.1 - 3.7e-31 107.5 0.2 8.3e-31 106.4 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase DUF1358 PF07096.11 OAG03017.1 - 0.14 12.1 1.8 0.46 10.5 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) adh_short PF00106.25 OAG03018.1 - 3.6e-34 118.0 0.0 4.5e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG03018.1 - 3.3e-27 95.5 0.0 4.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG03018.1 - 5.1e-06 26.5 0.0 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAG03018.1 - 0.029 13.8 0.0 2.8 7.3 0.0 2.7 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family TAL_FSA PF00923.19 OAG03020.1 - 3e-94 315.6 0.5 3.4e-94 315.4 0.5 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 OAG03020.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus SecD-TM1 PF13721.6 OAG03020.1 - 0.14 12.6 0.1 15 6.1 0.0 2.4 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Sod_Cu PF00080.20 OAG03021.1 - 8.3e-47 158.9 5.8 9.6e-47 158.7 5.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Astro_capsid_N PF03115.14 OAG03021.1 - 0.095 11.3 0.2 0.23 10.1 0.1 1.6 2 0 0 2 2 2 0 Astrovirus capsid protein precursor Caleosin PF05042.13 OAG03022.1 - 2e-79 265.4 0.0 2.5e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein zf-C2H2 PF00096.26 OAG03023.1 - 3.1e-11 43.1 8.8 2.1e-05 24.7 3.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG03023.1 - 2.1e-05 24.9 17.1 0.0044 17.8 2.0 3.8 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG03023.1 - 0.00051 20.3 1.4 1.5 9.2 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 OAG03023.1 - 0.00066 19.7 5.1 0.00066 19.7 5.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 OAG03023.1 - 0.0063 16.9 1.6 0.0063 16.9 1.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain ROS_MUCR PF05443.11 OAG03023.1 - 0.012 15.7 3.4 0.31 11.1 0.1 3.2 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2H2_11 PF16622.5 OAG03023.1 - 0.041 13.7 3.5 0.51 10.1 0.6 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF5339 PF17274.2 OAG03023.1 - 0.069 14.0 0.2 0.069 14.0 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Sec66 PF09802.9 OAG03023.1 - 0.086 12.4 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 zf-C2H2_6 PF13912.6 OAG03023.1 - 0.13 12.3 7.5 0.3 11.1 2.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 OAG03023.1 - 2.5 8.6 10.1 4.8 7.7 0.0 3.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Pkinase PF00069.25 OAG03029.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain TPR_1 PF00515.28 OAG03030.1 - 1.9e-35 119.2 24.4 2.3e-07 30.3 0.0 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAG03030.1 - 1.8e-29 99.5 30.5 9.8e-06 25.3 0.1 10.3 11 0 0 11 11 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG03030.1 - 7.9e-28 96.5 19.8 1.2e-21 76.7 0.8 5.2 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OAG03030.1 - 1.5e-26 90.3 17.2 0.0001 22.2 0.2 9.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG03030.1 - 5.7e-22 76.5 12.9 0.0024 18.6 0.0 9.0 7 1 3 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAG03030.1 - 8e-19 67.9 9.4 0.0029 18.1 0.3 8.4 5 1 3 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG03030.1 - 6.6e-18 64.8 21.0 0.0013 19.0 1.1 8.5 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAG03030.1 - 9e-18 63.7 14.2 0.012 15.3 0.0 8.2 5 2 3 8 8 8 4 TPR repeat TPR_16 PF13432.6 OAG03030.1 - 9.3e-16 58.2 18.8 0.0026 18.3 0.3 8.2 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG03030.1 - 8.4e-13 47.4 9.3 0.002 18.0 0.0 6.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAG03030.1 - 7.5e-10 38.5 12.7 2.2 8.8 0.1 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG03030.1 - 1.8e-09 37.6 7.4 3.5 8.5 0.1 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG03030.1 - 1.4e-05 24.5 5.6 0.0017 17.6 0.4 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 OAG03030.1 - 0.0011 19.4 3.1 0.063 13.7 0.2 3.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 OAG03030.1 - 0.0047 17.2 1.8 1.5 9.2 0.3 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG03030.1 - 0.0064 16.6 6.8 1.2 9.3 0.1 5.3 3 1 4 7 7 6 2 Tetratricopeptide repeat NARP1 PF12569.8 OAG03030.1 - 0.016 14.2 2.3 0.21 10.5 0.1 3.3 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 UPF0122 PF04297.14 OAG03030.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like TPR_10 PF13374.6 OAG03030.1 - 0.24 11.4 8.0 19 5.3 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 OAG03030.1 - 0.49 10.8 1.6 38 4.8 0.1 4.1 4 0 0 4 4 4 0 PPR repeat RPN7 PF10602.9 OAG03030.1 - 2.6 7.7 5.5 44 3.7 0.1 4.1 5 0 0 5 5 4 0 26S proteasome subunit RPN7 TMEM208_SND2 PF05620.11 OAG03031.1 - 1.2e-48 165.0 0.4 1.4e-48 164.9 0.4 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 NdhO PF11910.8 OAG03031.1 - 1.7 8.9 3.9 3.6 7.8 3.9 1.7 1 1 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O Bot1p PF12298.8 OAG03032.1 - 2.6e-50 170.9 1.3 2.6e-50 170.9 1.3 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein EFTUD2 PF16004.5 OAG03032.1 - 0.12 13.0 0.2 0.12 13.0 0.2 1.9 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Casein PF00363.18 OAG03032.1 - 1.2 9.5 3.8 12 6.3 0.2 3.2 3 0 0 3 3 3 0 Casein RRM_1 PF00076.22 OAG03033.1 - 2.4e-17 62.5 0.0 1.5e-13 50.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG03033.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif p450 PF00067.22 OAG03034.1 - 2e-58 198.3 0.0 3.5e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG03035.1 - 1.2e-63 214.8 1.5 1.4e-63 214.6 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG03035.1 - 3.5e-51 173.5 2.8 4.4e-51 173.1 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG03035.1 - 3.9e-16 59.5 1.0 5.6e-16 59.0 1.0 1.1 1 0 0 1 1 1 1 KR domain Ubie_methyltran PF01209.18 OAG03035.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 3HCDH_N PF02737.18 OAG03035.1 - 0.074 12.9 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG03035.1 - 0.13 11.7 0.3 0.2 11.1 0.3 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 OAG03036.1 - 8.4e-16 58.1 0.0 1.2e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG03036.1 - 1.8e-07 30.7 0.0 0.0049 16.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG03036.1 - 2.7e-07 30.5 0.3 0.00094 18.9 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG03036.1 - 4.5e-07 30.3 0.1 0.014 16.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG03036.1 - 9.3e-05 22.6 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG03036.1 - 0.024 13.4 0.0 0.76 8.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 OAG03036.1 - 0.03 13.2 0.6 2.7 6.7 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 OAG03036.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG03036.1 - 0.066 12.5 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 OAG03037.1 - 8.7e-12 44.6 0.2 1.4e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03037.1 - 1.5e-09 37.8 7.1 3e-09 36.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUC130_3NT PF08158.12 OAG03037.1 - 0.04 14.2 0.0 0.45 10.9 0.0 2.5 3 0 0 3 3 3 0 NUC130/3NT domain HeLo PF14479.6 OAG03039.1 - 6.8e-08 32.6 0.0 0.0035 17.2 0.1 2.7 2 0 0 2 2 2 2 Prion-inhibition and propagation Pkinase PF00069.25 OAG03039.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03039.1 - 0.019 14.2 0.0 0.069 12.4 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAG03039.1 - 0.3 10.0 0.1 0.45 9.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DDA1 PF10172.9 OAG03040.1 - 0.041 14.1 1.2 0.071 13.4 1.2 1.5 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase MscL PF01741.18 OAG03041.1 - 4e-19 69.1 0.2 4.8e-19 68.8 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DUF1422 PF07226.11 OAG03041.1 - 0.3 11.1 1.9 0.3 11.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) DUF952 PF06108.12 OAG03042.1 - 4.2e-20 71.5 0.0 5.4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DJ-1_PfpI PF01965.24 OAG03044.1 - 4.2e-05 23.4 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Amino_oxidase PF01593.24 OAG03045.1 - 6.2e-50 170.8 0.0 7.6e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG03045.1 - 6.8e-12 45.4 0.4 1.5e-11 44.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG03045.1 - 3.2e-08 33.1 0.1 5.3e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG03045.1 - 5.7e-08 32.5 0.0 2.5e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OAG03045.1 - 9.2e-07 28.8 0.0 2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG03045.1 - 2.7e-06 26.7 0.2 4.7e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OAG03045.1 - 2.1e-05 23.8 0.0 3.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAG03045.1 - 4.4e-05 22.9 0.0 8.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG03045.1 - 7.2e-05 21.7 0.1 0.00011 21.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG03045.1 - 0.0055 15.8 0.1 0.0096 15.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG03045.1 - 0.007 15.6 0.1 0.16 11.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG03045.1 - 0.026 13.8 0.5 0.062 12.5 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 OAG03045.1 - 0.037 14.6 0.1 0.17 12.5 0.1 2.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG03045.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AA_permease_2 PF13520.6 OAG03046.1 - 1.8e-47 162.1 55.3 2.1e-47 161.9 55.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG03046.1 - 7.7e-17 61.0 48.3 1.1e-16 60.5 48.3 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 OAG03047.1 - 2.9e-23 82.3 0.2 1.4e-11 43.8 0.1 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03047.1 - 1.9e-05 24.7 9.4 3.8e-05 23.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRKG1_interact PF15898.5 OAG03047.1 - 0.063 14.2 0.3 0.16 12.8 0.3 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain adh_short_C2 PF13561.6 OAG03048.1 - 1.7e-57 194.7 1.1 1.9e-57 194.5 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG03048.1 - 8.3e-39 133.1 2.3 1.1e-38 132.7 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG03048.1 - 1.1e-10 41.7 0.1 1.6e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF3150 PF11348.8 OAG03048.1 - 0.044 13.0 0.1 0.081 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) AIRC PF00731.20 OAG03048.1 - 0.076 12.6 0.7 0.54 9.8 0.3 2.2 2 0 0 2 2 2 0 AIR carboxylase Peptidase_M13 PF01431.21 OAG03048.1 - 0.24 11.0 1.3 3 7.4 0.0 2.3 1 1 1 2 2 2 0 Peptidase family M13 Fungal_trans PF04082.18 OAG03049.1 - 7.1e-23 81.0 0.9 1.2e-22 80.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03049.1 - 4e-07 30.1 6.4 4e-07 30.1 6.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM184 PF15665.5 OAG03050.1 - 0.0019 18.0 1.0 0.0023 17.8 1.0 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B DUF5320 PF17253.2 OAG03050.1 - 0.019 16.0 0.0 0.022 15.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF3287 PF11690.8 OAG03050.1 - 0.037 13.8 0.6 0.043 13.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF883 PF05957.13 OAG03050.1 - 0.055 14.1 0.9 0.07 13.7 0.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Bap31_Bap29_C PF18035.1 OAG03050.1 - 0.069 13.2 2.2 0.078 13.0 0.5 1.8 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DASH_Dam1 PF08653.10 OAG03050.1 - 0.075 12.8 2.0 0.22 11.3 2.0 1.7 1 1 0 1 1 1 0 DASH complex subunit Dam1 ADH_N PF08240.12 OAG03051.1 - 7.1e-30 103.1 0.9 1.1e-29 102.5 0.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG03051.1 - 1.1e-25 90.1 0.0 1.9e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG03051.1 - 3.1e-09 36.7 0.1 4.1e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG03051.1 - 5e-09 37.3 0.0 9.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG03051.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG03051.1 - 0.089 12.1 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PI3_PI4_kinase PF00454.27 OAG03052.1 - 3.5e-51 174.4 0.0 7.8e-51 173.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 OAG03052.1 - 1.3e-31 109.8 0.9 1.3e-31 109.8 0.9 4.7 6 0 0 6 6 6 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 OAG03052.1 - 1.8e-10 40.5 0.0 4.1e-09 36.1 0.0 2.8 2 0 0 2 2 2 1 FATC domain Nup192 PF11894.8 OAG03053.1 - 0 1396.2 3.9 0 1396.0 3.9 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF3361 PF11841.8 OAG03053.1 - 0.041 13.8 0.2 0.52 10.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) ADH_zinc_N_2 PF13602.6 OAG03054.1 - 1.6e-20 74.5 0.0 6.3e-20 72.6 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG03054.1 - 4.3e-11 42.9 0.3 8.8e-11 41.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG03054.1 - 0.017 14.4 1.2 0.027 13.8 1.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.8 OAG03054.1 - 0.2 11.4 0.8 0.55 10.0 0.3 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GCV_H PF01597.19 OAG03055.1 - 2.4e-37 127.5 0.6 2.9e-37 127.3 0.6 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 OAG03055.1 - 0.029 14.3 0.2 0.049 13.6 0.1 1.4 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Ribosomal_S6 PF01250.17 OAG03056.1 - 8.8e-24 83.6 0.0 1.1e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 TRI12 PF06609.13 OAG03057.1 - 8.1e-44 150.0 22.0 1.9e-33 115.7 12.1 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG03057.1 - 1.1e-17 64.0 58.2 9.9e-13 47.7 29.7 3.6 3 2 0 3 3 3 2 Major Facilitator Superfamily CopD PF05425.13 OAG03057.1 - 0.1 13.0 0.0 0.1 13.0 0.0 4.9 2 1 3 5 5 5 0 Copper resistance protein D SKG6 PF08693.10 OAG03058.1 - 0.0027 17.1 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG03058.1 - 0.0087 16.2 1.1 0.013 15.6 1.1 1.4 1 0 0 1 1 1 1 Podoplanin Gly-zipper_OmpA PF13436.6 OAG03058.1 - 0.11 12.3 3.7 0.26 11.1 3.7 1.6 1 0 0 1 1 1 0 Glycine-zipper domain SNase PF00565.17 OAG03061.1 - 8.9e-73 241.7 0.5 2.3e-25 89.1 0.0 5.6 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OAG03061.1 - 4.8e-25 87.9 0.0 1.3e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 OAG03061.1 - 0.012 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Agenet PF05641.12 OAG03061.1 - 0.015 15.7 0.1 0.11 13.0 0.1 2.4 2 0 0 2 2 2 0 Agenet domain WD40 PF00400.32 OAG03063.1 - 1.6e-23 82.5 8.4 3.6e-08 33.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG03063.1 - 1.4e-09 38.1 0.3 0.0093 16.2 0.0 3.6 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG03063.1 - 1.2e-05 24.4 0.1 0.0034 16.4 0.0 3.0 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG03063.1 - 0.0021 16.8 2.2 0.2 10.3 0.2 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 MetallophosC PF16370.5 OAG03063.1 - 0.032 14.5 0.2 0.98 9.6 0.1 2.5 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Kelch_6 PF13964.6 OAG03063.1 - 0.052 13.8 1.1 13 6.2 0.0 3.9 4 0 0 4 4 4 0 Kelch motif MFS_1 PF07690.16 OAG03064.1 - 3e-32 111.9 33.1 3e-32 111.9 33.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG03064.1 - 0.00021 20.7 9.5 0.00021 20.7 9.5 2.0 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Chitin_bind_1 PF00187.19 OAG03066.1 - 1.5e-18 67.0 88.6 8.3e-08 32.6 21.8 4.0 4 0 0 4 4 4 3 Chitin recognition protein ApbA PF02558.16 OAG03067.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Abhydrolase_1 PF00561.20 OAG03068.1 - 5.6e-19 68.8 0.1 1e-18 68.0 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG03068.1 - 1.5e-12 48.6 4.6 2e-12 48.2 4.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG03068.1 - 2e-06 27.2 0.0 4.8e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 OAG03068.1 - 0.29 10.4 1.0 0.41 9.9 1.0 1.1 1 0 0 1 1 1 0 Secretory lipase Podoplanin PF05808.11 OAG03069.1 - 0.0025 18.0 0.5 0.0085 16.2 0.4 1.9 2 0 0 2 2 2 1 Podoplanin Gram_pos_anchor PF00746.21 OAG03069.1 - 0.06 13.3 2.6 0.14 12.1 2.6 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TauE PF01925.19 OAG03069.1 - 0.18 11.4 5.1 0.33 10.6 5.1 1.4 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Peptidase_M73 PF12389.8 OAG03069.1 - 0.21 11.4 0.1 0.33 10.8 0.1 1.2 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase DUF4366 PF14283.6 OAG03069.1 - 0.32 11.0 0.0 0.32 11.0 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) SLATT_fungal PF18142.1 OAG03069.1 - 1.3 9.0 4.9 2.4 8.2 4.9 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain FAD_binding_1 PF00667.20 OAG03070.1 - 4.1e-47 160.6 0.0 5.9e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAG03070.1 - 1.5e-09 38.5 0.0 3.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HTH_IclR PF09339.10 OAG03071.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain ABC_membrane PF00664.23 OAG03072.1 - 6.8e-52 176.8 9.0 8.7e-52 176.4 9.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG03072.1 - 4.3e-35 121.2 0.0 1.4e-34 119.5 0.0 1.9 2 0 0 2 2 1 1 ABC transporter Cupin_2 PF07883.11 OAG03072.1 - 1.4e-13 50.3 0.2 3.1e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG03072.1 - 4.3e-06 26.7 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain SMC_N PF02463.19 OAG03072.1 - 2.8e-05 23.7 0.0 0.00012 21.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ARD PF03079.14 OAG03072.1 - 0.00063 20.0 0.3 0.0016 18.6 0.0 1.9 2 0 0 2 2 2 1 ARD/ARD' family AAA_22 PF13401.6 OAG03072.1 - 0.0028 17.9 0.2 0.024 14.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain Cupin_6 PF12852.7 OAG03072.1 - 0.0029 17.4 0.1 0.0068 16.2 0.1 1.6 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG03072.1 - 0.004 16.8 0.2 0.0094 15.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 OAG03072.1 - 0.0094 15.6 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 1 Cupin AAA_16 PF13191.6 OAG03072.1 - 0.026 14.9 0.1 0.095 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 OAG03072.1 - 0.033 13.9 0.2 0.84 9.4 0.2 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 OAG03072.1 - 0.074 13.5 0.0 0.35 11.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 OAG03072.1 - 0.11 12.8 0.8 1.5 9.1 0.8 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 OAG03072.1 - 0.11 12.3 0.1 4.6 6.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein MIF4G_like_2 PF09090.11 OAG03072.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 MIF4G like RTC PF01137.21 OAG03073.1 - 6.5e-59 198.8 0.0 8e-59 198.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF3176 PF11374.8 OAG03074.1 - 1.4e-19 70.2 0.3 1.8e-19 69.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) PD40 PF07676.12 OAG03077.1 - 0.02 14.8 0.4 5.3 7.1 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Zn_clus PF00172.18 OAG03080.1 - 2.6e-05 24.2 8.5 2.6e-05 24.2 8.5 2.6 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_I PF00867.18 OAG03081.1 - 1.8e-25 89.1 0.0 3.6e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OAG03081.1 - 1.1e-05 25.8 0.0 2.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 OAG03081.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing Transp_cyt_pur PF02133.15 OAG03082.1 - 4.8e-150 500.2 35.6 5.6e-150 500.0 35.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Urb2 PF10441.9 OAG03083.1 - 7e-46 156.8 0.9 4.1e-45 154.2 0.0 2.8 3 0 0 3 3 3 1 Urb2/Npa2 family DUF543 PF04418.12 OAG03084.1 - 1.2e-30 105.3 0.0 1.3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) CHORD PF04968.12 OAG03085.1 - 2.4 8.9 9.7 0.64 10.8 0.3 2.7 2 1 0 2 2 2 0 CHORD CDH-cyt PF16010.5 OAG03086.1 - 2.3e-52 177.3 0.0 2.9e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase TMEM154 PF15102.6 OAG03089.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family TMEM51 PF15345.6 OAG03089.1 - 0.006 16.4 0.1 0.0082 16.0 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 MGC-24 PF05283.11 OAG03089.1 - 0.027 14.9 7.1 0.034 14.6 6.6 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Podoplanin PF05808.11 OAG03089.1 - 0.04 14.0 0.7 0.074 13.1 0.7 1.4 1 0 0 1 1 1 0 Podoplanin Mid2 PF04478.12 OAG03089.1 - 0.079 12.8 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 OAG03089.1 - 0.09 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain SSP160 PF06933.11 OAG03089.1 - 0.14 10.3 9.1 0.19 9.9 9.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CENP-O PF09496.10 OAG03090.1 - 0.011 15.7 0.4 0.016 15.2 0.4 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component GST_N_3 PF13417.6 OAG03094.1 - 8.4e-10 38.9 0.1 6.9e-09 36.0 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG03094.1 - 2.9e-07 30.7 0.0 6.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG03094.1 - 0.00034 20.7 0.0 0.00087 19.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG03094.1 - 0.0016 18.4 0.1 0.0045 17.0 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG03094.1 - 0.0028 17.8 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG03094.1 - 0.015 15.8 0.0 0.028 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EthD PF07110.11 OAG03095.1 - 0.019 16.1 0.2 0.06 14.5 0.2 1.7 1 1 0 1 1 1 0 EthD domain Apc13p PF05839.11 OAG03096.1 - 2.3e-28 98.2 0.3 2.6e-28 98.1 0.3 1.0 1 0 0 1 1 1 1 Apc13p protein GFA PF04828.14 OAG03097.1 - 8.8e-16 58.0 0.1 1.3e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 OAG03097.1 - 0.12 12.2 7.1 0.2 11.4 0.3 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Peptidase_S8 PF00082.22 OAG03098.1 - 1.2e-41 143.0 0.0 2.5e-41 141.9 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAG03098.1 - 3.8e-17 63.0 0.5 9.5e-17 61.7 0.5 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 OAG03098.1 - 1.8e-05 24.7 0.4 6.5e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 PA domain Calycin_like PF13944.6 OAG03098.1 - 0.034 14.5 1.8 0.11 12.8 1.8 2.0 1 1 0 1 1 1 0 Calycin-like beta-barrel domain Glyco_hydro_18 PF00704.28 OAG03099.1 - 5.1e-26 92.1 1.6 4.8e-25 88.9 1.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans_2 PF11951.8 OAG03101.1 - 2.5e-06 26.6 0.2 4.4e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03101.1 - 4.3e-06 26.8 5.9 7.6e-06 26.0 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG03103.1 - 5.9e-44 150.4 59.0 3.2e-41 141.4 54.1 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03103.1 - 0.0027 16.6 15.0 0.0027 16.6 15.0 3.1 3 2 0 3 3 3 2 Sugar (and other) transporter GFO_IDH_MocA PF01408.22 OAG03104.1 - 6e-18 65.8 0.0 1.1e-17 64.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG03104.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PseudoU_synth_2 PF00849.22 OAG03105.1 - 4.4e-27 95.1 0.0 8e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OAG03105.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ntox30 PF15532.6 OAG03105.1 - 0.061 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 30 DUF2950 PF11453.8 OAG03105.1 - 0.14 11.4 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) peroxidase PF00141.23 OAG03107.1 - 1.2e-30 106.9 0.0 2e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 OAG03107.1 - 0.0042 17.0 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region DUF1923 PF09083.10 OAG03107.1 - 0.083 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) SET PF00856.28 OAG03108.1 - 5.2e-12 46.5 0.0 3.1e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 SET domain PhoLip_ATPase_C PF16212.5 OAG03109.1 - 4e-70 236.4 25.2 4e-70 236.4 25.2 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG03109.1 - 5.8e-24 83.6 6.8 7.6e-23 80.0 0.3 3.2 3 0 0 3 3 3 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAG03109.1 - 1.9e-14 54.4 0.3 1e-09 39.0 0.3 3.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG03109.1 - 2.9e-12 46.5 0.0 3.1e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAG03109.1 - 1.5e-09 37.6 0.0 1.6e-08 34.3 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAG03109.1 - 0.0012 18.7 0.0 0.004 16.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3090 PF11290.8 OAG03109.1 - 0.25 11.1 1.8 0.3 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) zf-MYND PF01753.18 OAG03110.1 - 0.88 9.7 8.8 1.9 8.7 8.8 1.6 1 0 0 1 1 1 0 MYND finger CorA PF01544.18 OAG03111.1 - 1.8e-29 103.0 7.1 1.9e-24 86.5 4.8 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein EMP70 PF02990.16 OAG03111.1 - 0.16 10.6 1.7 0.23 10.1 1.7 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 GDA1_CD39 PF01150.17 OAG03113.1 - 9.8e-95 317.7 0.0 1.2e-94 317.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 OAG03113.1 - 0.23 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family ABA_WDS PF02496.16 OAG03115.1 - 0.024 15.1 0.3 0.054 14.0 0.3 1.5 1 0 0 1 1 1 0 ABA/WDS induced protein Glyco_hydro_18 PF00704.28 OAG03116.1 - 1.2e-60 205.9 0.5 1.5e-60 205.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG03116.1 - 2e-05 25.0 18.1 2e-05 25.0 18.1 1.7 2 0 0 2 2 2 1 Chitin recognition protein eIF-5a PF01287.20 OAG03118.1 - 6e-06 26.3 0.2 1.3e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DIOX_N PF14226.6 OAG03119.1 - 7.8e-13 49.2 0.0 1.3e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG03119.1 - 0.00026 21.4 0.0 0.00068 20.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1682 PF07946.14 OAG03121.1 - 2.6e-112 375.2 0.8 3e-112 375.0 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Atg14 PF10186.9 OAG03121.1 - 6.7 5.7 7.2 9.5 5.2 7.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COX7a PF02238.15 OAG03122.1 - 7.2e-16 58.3 0.8 8.6e-16 58.1 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Corona_5a PF06336.11 OAG03122.1 - 0.074 13.0 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Coronavirus 5a protein CAF1-p150_C2 PF15539.6 OAG03123.1 - 0.051 13.0 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term IF2_assoc PF08364.11 OAG03124.1 - 0.67 10.3 2.1 1.5 9.1 2.1 1.5 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region FAD_binding_3 PF01494.19 OAG03125.1 - 7e-77 259.0 0.0 8.8e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG03125.1 - 2.3e-45 154.6 0.0 4.6e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 OAG03125.1 - 0.0066 15.5 0.0 0.26 10.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 OAG03125.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG03125.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MKT1_C PF12246.8 OAG03128.1 - 6.1e-74 248.3 0.0 6.9e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication 2OG-FeII_Oxy PF03171.20 OAG03130.1 - 5.8e-17 62.0 0.0 1.4e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG03130.1 - 6.1e-15 56.0 0.0 1e-14 55.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PTCB-BRCT PF12738.7 OAG03131.1 - 1.8e-44 149.5 1.5 1.3e-23 82.7 0.3 4.3 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 OAG03131.1 - 1.4e-31 108.7 0.0 9.5e-15 54.7 0.0 4.6 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG03131.1 - 8.9e-14 51.7 0.0 4.2e-05 23.9 0.0 4.8 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG03131.1 - 7.7e-07 29.3 1.9 0.61 10.4 0.0 3.8 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 OAG03131.1 - 0.075 13.1 0.0 4.8 7.3 0.0 3.5 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain Arrestin_C PF02752.22 OAG03132.1 - 5.4e-22 78.7 0.0 2.5e-20 73.3 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAG03132.1 - 4e-09 36.7 0.0 5.8e-05 23.2 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bd3614-deam PF14439.6 OAG03133.1 - 0.21 11.6 0.1 0.21 11.6 0.1 1.7 1 1 1 2 2 2 0 Bd3614-like deaminase Nha1_C PF08619.10 OAG03134.1 - 2.2e-83 281.0 50.0 8.4e-79 265.9 36.0 2.7 1 1 2 3 3 3 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 OAG03134.1 - 3e-78 263.3 15.5 3.6e-78 263.0 15.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 OAG03134.1 - 0.66 10.1 3.8 0.43 10.7 0.5 2.2 2 0 0 2 2 2 0 YrhC-like protein Glyco_hydro_28 PF00295.17 OAG03135.1 - 4.4e-09 35.8 0.2 1.1e-08 34.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_49 PF03718.13 OAG03135.1 - 0.061 13.3 1.7 52 3.9 0.1 3.7 1 1 1 4 4 4 0 Glycosyl hydrolase family 49 MoeA_C PF03454.15 OAG03136.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Glyco_hydro_17 PF00332.18 OAG03137.1 - 1.2e-10 41.5 3.6 2.9e-05 23.8 1.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Trep_Strep PF09605.10 OAG03137.1 - 0.077 13.0 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF3482 PF11981.8 OAG03137.1 - 0.13 11.6 4.4 0.47 9.8 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) NACHT PF05729.12 OAG03138.1 - 1.5e-09 38.0 0.1 2e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAG03138.1 - 4.3e-06 27.1 0.0 2.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG03138.1 - 2.7e-05 24.6 2.6 6.3e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 OAG03138.1 - 0.014 15.9 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAG03138.1 - 0.017 14.4 1.1 0.032 13.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 OAG03138.1 - 0.017 15.5 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 OAG03138.1 - 0.038 13.2 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 OAG03138.1 - 0.056 13.6 2.0 0.066 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 OAG03138.1 - 0.13 12.4 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Torsin AAA_18 PF13238.6 OAG03138.1 - 0.13 12.8 0.3 0.66 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain EthD PF07110.11 OAG03139.1 - 0.025 15.7 0.0 0.039 15.1 0.0 1.5 1 0 0 1 1 1 0 EthD domain CNH PF00780.22 OAG03140.1 - 5.9e-80 268.8 0.0 4.3e-79 266.0 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 OAG03140.1 - 8.9e-47 158.6 0.1 8.9e-47 158.6 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 OAG03140.1 - 9.4e-40 136.8 0.4 2.1e-39 135.7 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAG03140.1 - 1.2e-15 57.2 0.1 5.2e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 OAG03140.1 - 0.081 13.4 0.0 0.77 10.3 0.0 2.6 2 0 0 2 2 2 0 PH domain ATP-synt_C PF00137.21 OAG03141.1 - 2.2e-31 107.9 33.2 7.4e-20 71.1 13.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.25 OAG03142.1 - 3.1e-66 223.5 0.0 3.9e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03142.1 - 4.4e-34 117.9 0.0 5.9e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG03142.1 - 7.2e-05 22.8 0.0 0.021 14.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG03142.1 - 0.003 16.6 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG03142.1 - 0.0083 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OAG03142.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 OAG03142.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 OAG03142.1 - 0.096 12.3 0.0 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4690 PF15756.5 OAG03143.1 - 0.0056 17.2 0.3 0.019 15.6 0.3 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage CYYR1 PF10873.8 OAG03143.1 - 0.026 15.0 0.1 0.026 15.0 0.1 2.2 2 1 0 3 3 3 0 Cysteine and tyrosine-rich protein 1 TPPK_C PF12555.8 OAG03143.1 - 0.11 12.6 2.9 0.21 11.7 2.9 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal LapA_dom PF06305.11 OAG03143.1 - 0.26 11.1 1.1 0.47 10.3 1.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GST_C PF00043.25 OAG03144.1 - 1.1e-15 57.6 0.3 9e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG03144.1 - 1.2e-11 44.7 0.0 5.2e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG03144.1 - 5.5e-08 33.0 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG03144.1 - 5.8e-07 29.4 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG03144.1 - 4.2e-06 27.0 0.0 7.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG03144.1 - 1.4e-05 25.5 0.0 2.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Mistic PF11458.8 OAG03144.1 - 0.098 12.6 3.9 0.16 11.9 1.2 2.2 2 0 0 2 2 2 0 Membrane-integrating protein Mistic MARVEL PF01284.23 OAG03146.1 - 1.8e-07 31.3 10.5 1.8e-07 31.3 10.5 1.5 1 1 1 2 2 2 1 Membrane-associating domain Thia_YuaJ PF09515.10 OAG03146.1 - 0.13 12.2 9.0 6.8 6.7 7.1 2.1 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) TMEM192 PF14802.6 OAG03146.1 - 0.24 10.5 3.6 1.8 7.6 0.3 2.0 1 1 1 2 2 2 0 TMEM192 family VIT1 PF01988.19 OAG03146.1 - 0.25 11.2 1.7 0.29 11.0 1.7 1.1 1 0 0 1 1 1 0 VIT family XhlA PF10779.9 OAG03146.1 - 6 7.1 6.3 11 6.3 0.8 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Annexin PF00191.20 OAG03147.1 - 5e-64 212.3 6.4 9.3e-20 70.5 0.2 4.3 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 OAG03147.1 - 0.0018 18.0 1.0 1.3 8.9 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3574) Extensin_2 PF04554.13 OAG03147.1 - 0.0039 17.2 86.5 0.19 11.8 32.0 3.6 1 1 2 3 3 3 2 Extensin-like region Glyco_transf_88 PF16849.5 OAG03147.1 - 0.11 11.4 0.0 2.5 6.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 88 C166 PF17615.2 OAG03148.1 - 0.00031 20.9 0.2 0.00031 20.9 0.2 2.7 3 1 0 3 3 3 1 Family of unknown function p450 PF00067.22 OAG03149.1 - 1e-58 199.3 0.0 1.2e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 OAG03149.1 - 0.19 11.5 1.1 0.4 10.5 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) RseC_MucC PF04246.12 OAG03150.1 - 2.6 8.0 5.7 8.9 6.3 0.5 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ADH_zinc_N PF00107.26 OAG03151.1 - 6.8e-12 45.5 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG03151.1 - 7.1e-08 32.3 2.3 1.1e-07 31.6 0.3 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAG03151.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase RVT_1 PF00078.27 OAG03153.1 - 4.1e-09 36.3 0.0 7.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YbjQ_1 PF01906.17 OAG03153.1 - 0.04 14.6 0.0 0.12 13.1 0.0 1.8 1 1 1 2 2 2 0 Putative heavy-metal-binding AMP-binding PF00501.28 OAG03154.1 - 4.9e-92 308.7 0.0 6.7e-92 308.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RabGAP-TBC PF00566.18 OAG03154.1 - 2.6e-47 161.3 0.0 3.8e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AMP-binding_C PF13193.6 OAG03154.1 - 4.3e-17 62.9 0.4 1.1e-16 61.5 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_6 PF13405.6 OAG03154.1 - 0.00048 19.8 0.6 0.061 13.3 0.2 3.5 2 0 0 2 2 2 1 EF-hand domain GRAM PF02893.20 OAG03154.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 GRAM domain EF-hand_7 PF13499.6 OAG03154.1 - 0.023 15.1 1.6 0.12 12.8 0.5 2.9 1 1 2 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 OAG03154.1 - 0.038 13.6 2.2 0.33 10.6 0.6 3.3 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.6 OAG03154.1 - 0.11 12.1 0.2 0.4 10.3 0.2 2.0 1 0 0 1 1 1 0 EF hand adh_short_C2 PF13561.6 OAG03155.1 - 1.1e-55 188.8 0.2 1.7e-55 188.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG03155.1 - 2.1e-41 141.5 0.2 2.9e-41 141.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG03155.1 - 1.9e-14 54.0 0.3 3e-14 53.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG03155.1 - 0.0042 16.6 0.2 0.0091 15.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG03155.1 - 0.0085 16.0 0.0 0.027 14.3 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG03155.1 - 0.0093 15.4 0.0 3.5 6.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 OAG03155.1 - 0.075 13.0 0.3 0.34 10.9 0.2 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 OAG03155.1 - 0.085 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Exo_endo_phos PF03372.23 OAG03156.1 - 0.003 17.1 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pyr_redox_2 PF07992.14 OAG03158.1 - 1.4e-28 100.0 0.0 1.9e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG03158.1 - 1.2e-09 38.6 0.2 4e-09 36.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG03158.1 - 1.4e-06 27.9 0.0 3e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG03158.1 - 0.0014 17.9 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG03158.1 - 0.0083 15.7 0.0 0.11 12.0 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.18 OAG03158.1 - 0.023 14.9 0.0 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain DUF4149 PF13664.6 OAG03159.1 - 1.8e-22 79.6 0.8 2.6e-22 79.1 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) Fungal_trans PF04082.18 OAG03160.1 - 1.3e-07 31.0 1.3 2.7e-07 29.9 0.5 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03160.1 - 0.0095 16.0 9.8 0.017 15.2 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_3 PF13302.7 OAG03161.1 - 1.1e-17 65.0 0.0 1.5e-17 64.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG03161.1 - 1.7e-07 31.5 0.3 4.3e-07 30.2 0.1 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG03161.1 - 0.00021 21.2 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Zn_clus PF00172.18 OAG03162.1 - 1.3e-08 34.9 10.0 2.2e-08 34.1 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG03162.1 - 0.00051 19.2 0.4 0.0014 17.7 0.1 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 OAG03163.1 - 2.1e-19 71.0 2.3 2.5e-19 70.8 2.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG03163.1 - 7.1e-17 61.9 0.0 1.8e-12 47.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG03163.1 - 2.1e-12 46.9 0.0 3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG03163.1 - 0.00036 20.5 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 OAG03163.1 - 0.00057 20.1 0.0 0.00092 19.4 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 OAG03163.1 - 0.003 16.3 0.0 0.016 13.9 0.0 1.9 1 1 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 OAG03163.1 - 0.0076 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 OAG03163.1 - 0.051 13.5 0.0 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 OAG03163.1 - 0.093 12.5 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF5612 PF18462.1 OAG03163.1 - 0.15 11.8 0.1 2.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) Abhydrolase_3 PF07859.13 OAG03164.1 - 7.9e-08 32.4 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4175 PF13779.6 OAG03166.1 - 0.089 10.7 0.2 0.12 10.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Myb_DNA-binding PF00249.31 OAG03167.1 - 1.7e-08 34.5 0.4 4.1e-05 23.7 0.0 4.1 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG03167.1 - 0.00068 19.8 1.8 0.029 14.6 0.1 3.8 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAG03167.1 - 0.01 16.2 0.7 0.8 10.1 0.1 2.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG03167.1 - 0.014 15.2 0.7 1 9.3 0.0 3.2 2 1 1 3 3 3 0 Myb DNA-binding like Cnl2_NKP2 PF09447.10 OAG03167.1 - 0.073 13.2 0.6 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Cnl2/NKP2 family protein WD40 PF00400.32 OAG03169.1 - 1.3e-13 51.2 6.0 2.9e-07 31.1 0.3 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG03169.1 - 4.9e-06 26.8 0.0 0.068 13.5 0.0 4.0 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 OAG03170.1 - 8e-53 176.4 2.3 2.7e-18 65.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein peroxidase PF00141.23 OAG03171.1 - 1.4e-22 80.6 0.4 3e-22 79.5 0.4 1.5 1 0 0 1 1 1 1 Peroxidase Fungal_trans_2 PF11951.8 OAG03172.1 - 1.7e-08 33.7 3.5 2.4e-08 33.2 3.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03172.1 - 1.4e-07 31.5 11.6 2.4e-07 30.8 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain S1-like PF14444.6 OAG03172.1 - 0.21 11.5 0.3 28 4.7 0.1 2.4 2 0 0 2 2 2 0 S1-like RTA1 PF04479.13 OAG03173.1 - 1.1e-57 195.0 10.9 1.1e-57 195.0 10.9 2.7 1 1 1 2 2 2 1 RTA1 like protein ERGIC_N PF13850.6 OAG03173.1 - 0.063 13.6 0.9 0.36 11.2 0.4 2.5 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF347 PF03988.12 OAG03173.1 - 9.8 6.5 13.0 0.57 10.4 0.7 3.9 4 0 0 4 4 4 0 Repeat of Unknown Function (DUF347) SecY PF00344.20 OAG03174.1 - 1.9e-71 240.8 10.3 2.3e-71 240.5 10.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OAG03174.1 - 1.4e-16 60.1 0.2 3.5e-16 58.7 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p QCR10 PF09796.9 OAG03174.1 - 0.15 12.1 0.2 9.9 6.3 0.0 3.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Acetyltransf_7 PF13508.7 OAG03175.1 - 1.6e-09 38.0 0.0 3.8e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG03175.1 - 9.4e-09 35.3 0.0 1.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG03175.1 - 1.5e-08 34.9 0.0 2.9e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAG03175.1 - 1.4e-05 25.2 0.0 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG03175.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG03175.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein CENP-B_dimeris PF09026.10 OAG03179.1 - 3.5 8.1 9.6 7.8 6.9 9.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Anophelin PF10731.9 OAG03179.1 - 8.9 6.2 7.9 21 5.1 7.9 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Las1 PF04031.13 OAG03180.1 - 5.8e-40 136.9 1.5 9.2e-40 136.2 1.5 1.3 1 0 0 1 1 1 1 Las1-like adh_short PF00106.25 OAG03181.1 - 9.8e-20 70.8 0.1 2.1e-19 69.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG03181.1 - 5.7e-17 62.1 0.0 8.3e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG03181.1 - 6e-06 26.3 0.1 9e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG03181.1 - 8.8e-05 22.1 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TPR_12 PF13424.6 OAG03182.1 - 4.1e-09 36.6 1.5 3.8e-05 23.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG03182.1 - 8.2e-06 25.5 4.7 0.06 13.2 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG03182.1 - 0.023 15.5 0.8 36 5.5 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4835 PF16119.5 OAG03182.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) SAM_2 PF07647.17 OAG03182.1 - 0.14 12.3 0.2 0.31 11.2 0.2 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TPR_2 PF07719.17 OAG03182.1 - 0.93 9.8 4.0 2.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 OAG03183.1 - 1.3e-14 54.8 0.0 3.1e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG03183.1 - 0.00099 19.5 0.0 0.0026 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG03183.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG03183.1 - 0.0075 16.5 0.2 0.1 12.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain DnaB_C PF03796.15 OAG03183.1 - 0.11 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 OAG03183.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain GST_N_2 PF13409.6 OAG03184.1 - 3.3e-07 30.5 0.0 5.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG03184.1 - 1.1e-05 25.8 0.0 2.8e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cofilin_ADF PF00241.20 OAG03185.1 - 0.00031 20.5 0.0 0.00095 19.0 0.0 1.9 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein OHCU_decarbox PF09349.10 OAG03186.1 - 1.2e-50 172.0 0.1 1.4e-50 171.8 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF2733 PF10813.8 OAG03187.1 - 0.36 10.6 0.1 0.36 10.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) TRAPP PF04051.16 OAG03189.1 - 9.2e-39 132.5 0.0 1.1e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component AtuA PF07287.11 OAG03190.1 - 5.5e-127 423.3 0.5 6.5e-127 423.1 0.5 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA F-box PF00646.33 OAG03191.1 - 2.5e-08 33.6 0.1 1.3e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG03191.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like p450 PF00067.22 OAG03192.1 - 1e-56 192.7 0.0 5.8e-56 190.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 EMC1_C PF07774.13 OAG03193.1 - 1e-73 247.5 0.0 1.7e-73 246.9 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OAG03193.1 - 8.6e-32 110.6 2.5 1.2e-28 100.3 1.0 2.8 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 OAG03193.1 - 9.6e-08 31.6 2.9 0.62 10.1 0.0 5.0 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_3 PF13570.6 OAG03193.1 - 0.0009 19.7 0.1 29 5.3 0.0 5.7 5 0 0 5 5 5 1 PQQ-like domain Ras PF00071.22 OAG03194.1 - 4.5e-52 175.9 0.0 5.2e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG03194.1 - 4.2e-19 68.9 0.0 5.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG03194.1 - 3.9e-08 32.9 0.0 4.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG03194.1 - 0.00014 21.4 0.0 0.0026 17.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAG03194.1 - 0.00022 21.3 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG03194.1 - 0.0007 19.5 0.1 0.9 9.4 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAG03194.1 - 0.0075 16.6 0.4 0.3 11.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 OAG03194.1 - 0.11 11.8 0.0 1.1 8.5 0.0 2.1 1 1 0 2 2 2 0 Septin AAA_16 PF13191.6 OAG03194.1 - 0.21 12.0 1.3 1.6 9.1 1.3 2.4 1 1 0 1 1 1 0 AAA ATPase domain vWA-TerF-like PF10138.9 OAG03195.1 - 3.4e-08 33.9 0.0 4.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus BKACE PF05853.12 OAG03195.1 - 0.0085 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme p450 PF00067.22 OAG03196.1 - 7.1e-45 153.6 0.0 1.2e-44 152.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 OAG03197.1 - 1.8e-07 31.2 8.3 2.9e-07 30.5 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG03197.1 - 7.4e-06 25.0 0.0 1.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GPHH PF16905.5 OAG03198.1 - 0.038 13.8 0.3 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Melibiase PF02065.18 OAG03199.1 - 1.6e-137 458.2 0.0 2e-137 457.8 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 OAG03199.1 - 5.9e-75 252.1 0.0 1e-74 251.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 OAG03199.1 - 6.8e-24 84.2 0.0 1.7e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 OAG03199.1 - 5.5e-05 22.4 0.0 8.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Catalase PF00199.19 OAG03200.1 - 0.0084 15.3 0.0 0.024 13.7 0.0 1.8 1 1 0 1 1 1 1 Catalase 3Beta_HSD PF01073.19 OAG03201.1 - 0.00018 20.6 0.0 0.00019 20.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG03201.1 - 0.0026 17.0 0.0 0.0026 17.0 0.0 1.0 1 0 0 1 1 1 1 Male sterility protein Fimbrial_K88 PF02432.15 OAG03201.1 - 0.079 12.9 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Fimbrial, major and minor subunit Zn_clus PF00172.18 OAG03202.1 - 3.6e-07 30.2 9.0 6e-07 29.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 OAG03202.1 - 4.7e-06 26.3 2.9 4.7e-06 26.3 2.9 1.8 1 1 0 1 1 1 1 Aflatoxin regulatory protein FAD_binding_4 PF01565.23 OAG03204.1 - 3.4e-22 78.7 3.9 7e-22 77.7 3.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG03204.1 - 0.00017 21.6 0.2 0.00037 20.5 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Borrelia_P83 PF05262.11 OAG03206.1 - 0.39 9.2 14.6 0.48 8.9 14.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 OAG03206.1 - 0.57 10.0 27.9 0.074 12.9 20.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Macoilin PF09726.9 OAG03206.1 - 1.4 7.4 16.1 0.3 9.6 6.3 2.2 2 0 0 2 2 2 0 Macoilin family MFS_1 PF07690.16 OAG03207.1 - 6.1e-30 104.3 22.6 6.1e-30 104.3 22.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03207.1 - 1.9e-06 27.1 3.9 1.9e-06 27.1 3.9 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DZR PF12773.7 OAG03208.1 - 0.53 10.4 2.4 1 9.4 2.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Response_reg PF00072.24 OAG03209.1 - 3e-20 72.5 0.0 4.7e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Haspin_kinase PF12330.8 OAG03210.1 - 5.9e-35 120.9 0.0 3e-26 92.2 0.0 3.1 2 1 0 2 2 2 2 Haspin like kinase domain 5_nucleotid_C PF02872.18 OAG03211.1 - 0.0026 18.0 0.0 0.057 13.6 0.0 2.3 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain DUF4679 PF15728.5 OAG03211.1 - 0.019 14.0 0.6 0.027 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) ADH_zinc_N_2 PF13602.6 OAG03212.1 - 5.5e-16 59.8 0.0 1.2e-15 58.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG03212.1 - 1.3e-15 57.5 0.0 2.1e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG03212.1 - 0.046 13.6 0.1 0.17 11.8 0.1 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain CPSase_L_D2 PF02786.17 OAG03213.1 - 2e-70 236.6 0.0 2.9e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG03213.1 - 3e-37 127.5 0.0 6.1e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG03213.1 - 2.6e-36 124.0 0.0 1.3e-35 121.8 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG03213.1 - 3.4e-16 58.8 0.2 9e-16 57.5 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG03213.1 - 2.4e-09 37.0 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG03213.1 - 1.4e-08 34.5 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAG03213.1 - 0.0002 21.1 0.2 0.015 15.2 0.0 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 OAG03213.1 - 0.00023 21.8 0.0 1.4 9.7 0.0 3.3 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 OAG03213.1 - 0.00063 19.8 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 OAG03213.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.19 OAG03213.1 - 0.056 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein TraC_F_IV PF11130.8 OAG03214.1 - 0.045 13.3 0.3 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer CAF-1_p60_C PF15512.6 OAG03216.1 - 0.0091 16.5 0.3 0.0091 16.5 0.3 2.8 2 1 0 2 2 2 1 Chromatin assembly factor complex 1 subunit p60, C-terminal Peptidase_S64 PF08192.11 OAG03220.1 - 0.0052 15.3 0.4 0.93 7.9 0.2 2.1 2 0 0 2 2 2 2 Peptidase family S64 SRR1 PF07985.12 OAG03221.1 - 2.9e-12 46.5 0.0 5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.7 OAG03221.1 - 0.65 10.1 6.5 0.12 12.5 2.7 1.7 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain L31 PF09784.9 OAG03224.1 - 3.7e-45 152.5 1.0 4.1e-45 152.4 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF5470 PF17564.2 OAG03224.1 - 0.014 15.6 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5470) Sedlin_N PF04628.13 OAG03225.1 - 2.4e-31 108.6 0.0 2.8e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RINGv PF12906.7 OAG03226.1 - 4.8e-17 61.8 7.6 8.4e-17 61.0 7.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OAG03226.1 - 0.002 18.4 8.3 0.0035 17.6 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG03226.1 - 0.2 11.7 1.6 0.71 10.0 1.6 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1011 PF06237.12 OAG03226.1 - 0.26 11.6 4.9 0.28 11.5 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) DUF3899 PF13038.6 OAG03226.1 - 0.89 10.1 3.6 4.7 7.8 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) FANCL_C PF11793.8 OAG03226.1 - 1.4 9.2 5.6 6.3 7.1 4.6 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain Baculo_IE-1 PF05290.11 OAG03226.1 - 4.1 7.3 5.1 8.7 6.3 5.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TRAP_alpha PF03896.16 OAG03226.1 - 4.7 6.3 6.0 1.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF957 PF06117.11 OAG03227.1 - 0.15 11.7 0.6 2.9 7.5 0.0 3.2 3 0 0 3 3 3 0 Enterobacterial protein of unknown function (DUF957) Imm58 PF15581.6 OAG03227.1 - 0.18 11.9 0.7 2.1 8.5 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 58 FTA4 PF13093.6 OAG03227.1 - 1.7 8.5 5.8 5.5 6.8 1.2 3.5 3 1 0 3 3 3 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SSF PF00474.17 OAG03228.1 - 4.7e-18 65.2 30.9 6.7e-18 64.7 30.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Bac_luciferase PF00296.20 OAG03229.1 - 2.3e-54 185.0 0.8 3.2e-54 184.5 0.8 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase 2OG-FeII_Oxy_2 PF13532.6 OAG03230.1 - 2.2e-23 83.5 0.0 4.4e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG03231.1 - 3.8e-10 39.2 30.6 4.8e-10 38.9 26.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG03231.1 - 1.3e-05 25.0 3.5 3.1e-05 23.8 3.5 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 TauD PF02668.16 OAG03233.1 - 2.2e-39 135.9 0.1 2.8e-39 135.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BTB PF00651.31 OAG03234.1 - 2e-07 31.2 0.0 6e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain DUF3342 PF11822.8 OAG03234.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Lyase_aromatic PF00221.19 OAG03235.1 - 3.4e-149 497.4 4.1 4.7e-149 497.0 4.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Sugar-bind PF04198.13 OAG03235.1 - 0.05 12.7 0.4 0.24 10.5 0.1 2.1 2 0 0 2 2 2 0 Putative sugar-binding domain PI-PLC-X PF00388.19 OAG03236.1 - 1.1e-48 164.5 0.0 1.8e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAG03236.1 - 3e-36 124.3 0.0 4.8e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAG03236.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain HET PF06985.11 OAG03238.1 - 3.1e-17 63.3 0.4 6.6e-17 62.2 0.4 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 OAG03239.1 - 4.2e-25 88.7 0.0 5.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG03239.1 - 6.4e-20 71.4 0.0 8.3e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG03239.1 - 0.00026 20.9 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG03239.1 - 0.07 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cyclase PF04199.13 OAG03240.1 - 1.7e-14 54.2 0.1 2.4e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase DUF2397 PF09660.10 OAG03241.1 - 0.067 12.1 2.1 0.089 11.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Chs7 PF12271.8 OAG03242.1 - 5.6e-124 413.2 17.7 6.4e-124 413.0 17.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 OAG03242.1 - 0.0088 16.3 0.7 0.0088 16.3 0.7 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3382) DUF4281 PF14108.6 OAG03242.1 - 4.7 7.6 12.9 0.1 13.0 5.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4281) Dak1 PF02733.17 OAG03243.1 - 6.7e-101 337.3 0.6 1e-100 336.7 0.1 1.5 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 OAG03243.1 - 2.9e-38 131.5 0.9 5.1e-38 130.7 0.9 1.4 1 0 0 1 1 1 1 DAK2 domain ketoacyl-synt PF00109.26 OAG03244.1 - 5.7e-69 232.5 0.0 1.3e-68 231.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG03244.1 - 8.2e-50 170.1 0.2 1.9e-49 168.9 0.2 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG03244.1 - 3.2e-48 164.5 0.0 5.9e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAG03244.1 - 1.9e-46 158.2 0.1 6.8e-46 156.4 0.1 2.1 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 OAG03244.1 - 4.7e-32 110.5 0.0 1.1e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAG03244.1 - 9.1e-20 71.2 0.0 1.1e-18 67.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG03244.1 - 1.8e-15 57.2 0.0 1.5e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG03244.1 - 5.6e-15 55.8 0.0 1.4e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 OAG03244.1 - 2.9e-10 40.7 0.0 1.3e-09 38.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OAG03244.1 - 6.7e-10 38.8 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.12 OAG03244.1 - 1e-09 38.9 0.0 4.5e-09 36.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG03244.1 - 3.3e-09 36.7 0.0 1.2e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain SAT PF16073.5 OAG03244.1 - 3.4e-06 27.0 0.3 7.3e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_N PF08240.12 OAG03244.1 - 6.1e-06 26.1 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 OAG03244.1 - 1.7e-05 25.0 0.0 0.0001 22.6 0.0 2.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 OAG03244.1 - 5.4e-05 22.6 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 OAG03244.1 - 0.0034 16.8 0.0 0.08 12.3 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain NAD_binding_3 PF03447.16 OAG03244.1 - 0.0051 17.5 2.7 0.044 14.4 0.0 3.3 4 0 0 4 4 2 1 Homoserine dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 OAG03244.1 - 0.13 13.3 0.3 22 6.1 0.0 4.0 4 0 0 4 4 4 0 Zinc-binding dehydrogenase DUF3789 PF12664.7 OAG03244.1 - 0.2 11.4 1.1 0.54 10.0 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Methyltransf_28 PF02636.17 OAG03244.1 - 0.2 11.3 0.1 0.48 10.0 0.0 1.6 2 0 0 2 2 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FSH1 PF03959.13 OAG03245.1 - 5e-28 98.2 0.0 8.3e-28 97.5 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OAG03245.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 OAG03246.1 - 1.8e-22 80.2 0.2 2.8e-21 76.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG03246.1 - 4.7e-17 63.3 0.0 6.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG03246.1 - 2e-10 40.3 0.0 3.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 EHN PF06441.12 OAG03246.1 - 0.03 14.7 0.0 0.11 12.9 0.0 2.0 1 1 1 2 2 2 0 Epoxide hydrolase N terminus CMD PF02627.20 OAG03247.1 - 4.4e-05 23.5 0.3 7.5e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF2235 PF09994.9 OAG03249.1 - 2.2e-74 250.4 0.0 2.6e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) FMO-like PF00743.19 OAG03250.1 - 2.1e-15 56.2 0.1 7.5e-15 54.3 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG03250.1 - 1.1e-06 28.1 0.0 0.00011 21.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG03250.1 - 8.7e-06 25.9 0.0 8.6e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG03250.1 - 1.5e-05 24.5 0.0 3.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG03250.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XPB_DRD PF18458.1 OAG03250.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain Thi4 PF01946.17 OAG03250.1 - 0.049 12.9 0.0 7.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.15 OAG03250.1 - 0.093 11.3 0.1 0.45 9.0 0.1 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 OAG03250.1 - 0.094 12.7 0.2 7.2 6.6 0.0 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Glyoxalase PF00903.25 OAG03251.1 - 0.00026 21.2 0.0 0.00083 19.6 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG03251.1 - 0.055 14.3 0.0 0.071 13.9 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain CNH PF00780.22 OAG03252.1 - 6.2e-77 258.9 0.0 9.4e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 OAG03252.1 - 3.9e-31 108.7 0.3 6.6e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 OAG03252.1 - 1.4e-12 47.8 0.0 6.8e-11 42.4 0.0 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAG03252.1 - 0.0039 17.7 0.0 0.29 11.7 0.0 2.8 3 0 0 3 3 3 1 PH domain AA_permease PF00324.21 OAG03253.1 - 1.9e-123 412.6 40.3 2.4e-123 412.3 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG03253.1 - 1.3e-37 129.7 43.7 1.6e-37 129.4 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease Fil_haemagg_2 PF13332.6 OAG03254.1 - 0.049 13.7 5.2 0.12 12.5 5.2 1.5 1 0 0 1 1 1 0 Hemagglutinin repeat ETX_MTX2 PF03318.13 OAG03254.1 - 0.081 12.7 9.9 0.12 12.1 9.9 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF4981 PF16353.5 OAG03254.1 - 0.24 11.9 1.8 0.37 11.3 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function(DUF4981) Methyltransf_2 PF00891.18 OAG03255.1 - 1.1e-25 90.2 0.0 1.6e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAG03255.1 - 0.032 14.9 0.0 0.15 12.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF2237 PF09996.9 OAG03256.1 - 8.8e-20 70.8 0.0 1.2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) KRAP_IP3R_bind PF14722.6 OAG03256.1 - 0.16 11.7 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain HET PF06985.11 OAG03259.1 - 3.9e-12 46.7 9.7 1.4e-09 38.5 6.2 2.7 3 1 0 3 3 3 1 Heterokaryon incompatibility protein (HET) SNARE_assoc PF09335.11 OAG03260.1 - 0.052 14.0 0.0 0.088 13.3 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein GTP_EFTU PF00009.27 OAG03261.1 - 2.9e-58 196.6 0.0 6.2e-58 195.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OAG03261.1 - 1.3e-15 57.2 0.0 3.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG03261.1 - 3.7e-10 40.0 0.0 1.1e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAG03261.1 - 1.8e-06 27.9 0.0 3.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 OAG03261.1 - 0.017 14.9 0.0 0.061 13.1 0.0 1.9 1 0 0 1 1 1 0 Elongation factor G, domain IV MMR_HSR1 PF01926.23 OAG03261.1 - 0.074 13.1 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase PH PF00169.29 OAG03262.1 - 6.9e-29 100.5 1.0 6.2e-14 52.4 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 OAG03262.1 - 1.5e-11 44.7 5.1 3.3e-06 27.5 0.5 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 OAG03262.1 - 3.4e-09 37.1 4.4 0.0034 17.8 0.5 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 OAG03262.1 - 7.7e-07 29.3 0.5 7.4e-06 26.2 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 OAG03262.1 - 0.003 17.4 0.6 0.44 10.3 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_12 PF16457.5 OAG03262.1 - 0.012 16.2 0.9 22 5.6 1.0 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 OAG03262.1 - 0.081 13.2 0.1 11 6.4 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Mcp5_PH PF12814.7 OAG03262.1 - 0.11 12.6 1.0 7.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology BCL_N PF04714.13 OAG03262.1 - 2 8.5 5.4 1.3 9.1 1.2 2.8 2 0 0 2 2 2 0 BCL7, N-terminal conserver region HET PF06985.11 OAG03263.1 - 0.0066 16.8 0.0 0.0066 16.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CorA PF01544.18 OAG03264.1 - 6.7e-09 35.5 6.1 1.3e-07 31.2 3.5 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Glyco_hydro_61 PF03443.14 OAG03265.1 - 3.1e-23 82.8 0.0 3.8e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 WD40 PF00400.32 OAG03266.1 - 3.9e-07 30.7 1.1 0.074 13.9 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG03266.1 - 3.7e-05 23.9 0.2 0.043 14.1 0.1 3.5 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAG03266.1 - 0.0045 16.9 2.3 0.62 10.1 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat AAA_lid_2 PF17863.1 OAG03267.1 - 2.8e-06 27.1 0.7 1.1e-05 25.2 0.3 2.3 2 1 1 3 3 3 1 AAA lid domain NAD_kinase PF01513.21 OAG03268.1 - 2.2e-74 250.3 0.0 3.8e-74 249.5 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Porphobil_deam PF01379.20 OAG03269.1 - 1.2e-70 237.2 0.0 1.5e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OAG03269.1 - 1.1e-14 54.5 2.5 2.5e-13 50.2 2.5 2.4 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UCR_UQCRX_QCR9 PF05365.12 OAG03269.1 - 0.24 11.4 0.0 2.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like COesterase PF00135.28 OAG03270.1 - 0.00025 20.1 0.0 0.00027 20.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Aegerolysin PF06355.13 OAG03271.1 - 3.2e-05 24.0 0.2 0.00012 22.1 0.2 2.0 1 1 0 1 1 1 1 Aegerolysin HET PF06985.11 OAG03272.1 - 1e-33 116.7 1.6 2.1e-33 115.7 1.6 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TDH PF03347.13 OAG03273.1 - 0.048 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Self-incomp_S1 PF05938.11 OAG03274.1 - 0.0036 17.8 0.0 0.0055 17.2 0.0 1.3 1 0 0 1 1 1 1 Plant self-incompatibility protein S1 PSRT PF07636.11 OAG03274.1 - 0.016 14.9 0.2 0.016 14.9 0.2 2.3 2 0 0 2 2 2 0 PSRT HET PF06985.11 OAG03277.1 - 6e-24 85.0 0.1 9.7e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuclease PF00545.20 OAG03278.1 - 8.5e-10 39.2 0.2 1.3e-09 38.7 0.2 1.2 1 0 0 1 1 1 1 ribonuclease DUF4286 PF14114.6 OAG03279.1 - 0.069 13.7 0.0 0.29 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) TadF PF16964.5 OAG03281.1 - 0.045 13.5 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative tight adherence pilin protein F DUF2518 PF10726.9 OAG03281.1 - 0.071 12.8 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of function (DUF2518) Pectinesterase PF01095.19 OAG03283.1 - 1.7e-125 417.7 59.2 6.1e-41 140.1 6.8 5.8 4 2 1 5 5 5 5 Pectinesterase Helo_like_N PF17111.5 OAG03284.1 - 0.0029 17.0 3.2 0.43 9.9 0.2 2.2 1 1 1 2 2 2 2 Fungal N-terminal domain of STAND proteins RepB PF07506.11 OAG03284.1 - 0.029 14.5 0.6 0.26 11.4 0.0 2.2 1 1 1 2 2 2 0 RepB plasmid partitioning protein DUF2203 PF09969.9 OAG03284.1 - 0.046 14.4 0.1 0.082 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) PHD PF00628.29 OAG03285.1 - 1.1e-09 38.0 1.1 1.1e-09 38.0 1.1 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 OAG03285.1 - 0.034 13.7 2.1 0.061 12.9 2.1 1.4 1 0 0 1 1 1 0 PHD-finger BTB PF00651.31 OAG03287.1 - 0.0055 16.9 0.0 0.028 14.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain ADH_zinc_N PF00107.26 OAG03288.1 - 2.5e-13 50.1 0.2 3.9e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG03288.1 - 9.1e-08 32.0 0.0 2.2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAG03288.1 - 0.079 12.9 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase DUF2917 PF11142.8 OAG03288.1 - 0.17 11.3 0.6 6.2 6.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2917) adh_short PF00106.25 OAG03289.1 - 3.6e-09 36.4 0.1 5.1e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG03289.1 - 1.6e-05 24.9 0.2 3.2e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 OAG03289.1 - 0.0031 17.1 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PNTB PF02233.16 OAG03291.1 - 2e-174 580.9 24.5 2e-174 580.9 24.5 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 OAG03291.1 - 1.1e-72 243.8 0.1 3.2e-72 242.3 0.1 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 OAG03291.1 - 8e-43 146.0 0.0 2.1e-42 144.6 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 OAG03291.1 - 1.5e-30 105.5 3.1 1.5e-30 105.5 3.1 4.9 3 2 1 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 OAG03291.1 - 0.0016 17.8 0.2 0.56 9.5 0.1 3.0 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 OAG03291.1 - 0.0043 16.8 0.5 0.021 14.5 0.3 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.14 OAG03291.1 - 0.03 13.6 1.1 0.048 12.9 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 OAG03291.1 - 0.05 13.6 0.2 0.24 11.4 0.2 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Fumerase PF05681.14 OAG03291.1 - 0.063 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) PRIMA1 PF16101.5 OAG03291.1 - 0.078 13.0 2.3 0.22 11.5 2.3 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GIDA PF01134.22 OAG03291.1 - 0.093 11.8 1.1 0.16 11.0 1.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG03291.1 - 0.45 10.8 3.9 0.29 11.4 0.5 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Peptidase_M17_N PF02789.17 OAG03291.1 - 9 6.2 6.9 8.9 6.2 0.0 3.4 4 0 0 4 4 4 0 Cytosol aminopeptidase family, N-terminal domain Glyco_transf_90 PF05686.12 OAG03292.1 - 3.1e-15 56.0 5.9 8.1e-07 28.3 0.2 3.9 3 1 0 3 3 3 3 Glycosyl transferase family 90 IFT46_B_C PF12317.8 OAG03292.1 - 0.62 9.8 3.3 9.4 5.9 1.1 2.7 2 1 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal F-box-like PF12937.7 OAG03293.1 - 3.6e-09 36.4 0.1 4.9e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG03293.1 - 0.0063 16.4 0.5 0.038 13.9 0.5 2.0 1 1 0 1 1 1 1 F-box domain ZZ PF00569.17 OAG03294.1 - 0.00035 20.3 4.6 0.00074 19.3 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type FYVE PF01363.21 OAG03294.1 - 0.067 13.3 3.3 0.16 12.1 3.3 1.7 1 0 0 1 1 1 0 FYVE zinc finger TPR_14 PF13428.6 OAG03294.1 - 0.71 10.9 5.9 6.9 7.8 1.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG03294.1 - 3.1 8.1 5.1 2.6 8.3 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat C1_2 PF03107.16 OAG03294.1 - 4.6 7.6 9.4 9.5 6.6 9.4 1.5 1 0 0 1 1 1 0 C1 domain Aldo_ket_red PF00248.21 OAG03295.1 - 5.1e-73 245.8 0.0 6.1e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.25 OAG03296.1 - 5.3e-11 42.8 0.0 6.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG03296.1 - 4e-09 36.8 0.1 5.9e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG03296.1 - 4.9e-08 33.0 0.0 5.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG03296.1 - 0.0063 16.5 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAG03296.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 OAG03297.1 - 7.3e-50 169.8 0.0 1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03297.1 - 3e-27 95.6 0.2 1e-25 90.5 0.2 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG03297.1 - 0.0072 15.7 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG03297.1 - 0.11 11.2 0.0 0.27 9.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Spherulin4 PF12138.8 OAG03299.1 - 6e-49 166.9 1.1 6.9e-49 166.7 1.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 FliC_SP PF12613.8 OAG03299.1 - 0.53 10.8 3.2 0.4 11.2 0.5 2.3 2 1 1 3 3 3 0 Flagellin structural protein ABC_tran PF00005.27 OAG03300.1 - 2.5e-39 134.9 0.0 2.6e-18 66.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG03300.1 - 2.5e-26 92.9 38.7 3e-23 82.9 13.4 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG03300.1 - 1.9e-09 37.3 6.4 0.0086 15.5 0.1 4.6 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG03300.1 - 3.2e-08 33.8 3.6 0.4 10.4 0.1 4.7 3 2 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAG03300.1 - 8.7e-07 29.3 0.1 0.076 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG03300.1 - 1.1e-06 28.3 0.1 0.063 13.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG03300.1 - 1.4e-05 25.6 0.4 0.095 13.1 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.17 OAG03300.1 - 3.1e-05 24.2 0.1 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 OAG03300.1 - 4.6e-05 23.4 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 OAG03300.1 - 6e-05 22.2 0.0 0.02 13.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.6 OAG03300.1 - 9e-05 22.3 0.0 0.43 10.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OAG03300.1 - 0.00014 21.3 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 OAG03300.1 - 0.00017 21.7 0.2 0.69 10.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 OAG03300.1 - 0.00018 22.1 0.1 0.6 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 OAG03300.1 - 0.0003 21.2 0.0 1.7 9.1 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAG03300.1 - 0.00062 20.3 0.3 0.26 11.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 OAG03300.1 - 0.00063 19.8 1.4 0.058 13.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 OAG03300.1 - 0.00076 19.7 0.2 0.18 11.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG03300.1 - 0.0014 18.1 0.0 0.58 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OAG03300.1 - 0.0015 18.3 0.3 0.069 12.9 0.2 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.7 OAG03300.1 - 0.0059 15.6 0.0 0.51 9.2 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.22 OAG03300.1 - 0.0073 16.7 0.0 5.9 7.3 0.0 3.0 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 OAG03300.1 - 0.0074 15.9 0.3 0.74 9.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain PPV_E1_C PF00519.17 OAG03300.1 - 0.02 13.7 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase CLP1_P PF16575.5 OAG03300.1 - 0.035 13.9 0.1 0.96 9.2 0.0 2.7 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SbcCD_C PF13558.6 OAG03300.1 - 0.039 14.2 2.2 0.9 9.8 0.5 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 OAG03300.1 - 0.075 12.6 0.5 2.7 7.5 0.1 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 OAG03300.1 - 0.091 12.1 0.1 5.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG03300.1 - 0.092 12.7 0.1 9.9 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 OAG03300.1 - 0.1 12.6 0.0 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAG03300.1 - 0.12 12.3 0.1 18 5.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 OAG03300.1 - 0.15 11.8 3.3 7.2 6.3 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF815 PF05673.13 OAG03300.1 - 0.16 11.1 0.1 17 4.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase PF06745.13 OAG03300.1 - 0.17 11.2 0.3 13 5.1 0.0 3.2 3 1 0 3 3 3 0 KaiC Zeta_toxin PF06414.12 OAG03300.1 - 0.23 10.7 0.1 9.9 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 OAG03300.1 - 0.24 11.1 0.2 15 5.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain Alpha_L_fucos PF01120.17 OAG03301.1 - 1.7e-78 264.6 4.4 2.2e-78 264.1 4.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Spermine_synth PF01564.17 OAG03302.1 - 3.1e-05 23.5 0.0 5.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF2052 PF09747.9 OAG03303.1 - 1e-26 94.3 16.8 2.4e-13 50.6 12.1 2.2 1 1 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) MFS_1 PF07690.16 OAG03304.1 - 3.6e-38 131.4 34.4 3.6e-38 131.4 34.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03304.1 - 5.8e-11 41.9 19.3 9.4e-11 41.2 19.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TraL PF07178.11 OAG03304.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.9 4 2 0 4 4 4 0 TraL protein FAD_binding_3 PF01494.19 OAG03305.1 - 2.4e-22 79.7 0.7 3.1e-21 76.0 0.7 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG03305.1 - 0.00043 20.5 0.7 0.0014 18.9 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG03305.1 - 0.0028 17.0 0.6 0.0063 15.8 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG03305.1 - 0.007 15.4 0.0 0.81 8.7 0.0 2.3 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.27 OAG03305.1 - 0.012 16.2 1.0 0.065 13.8 0.7 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG03305.1 - 0.018 14.3 0.8 0.2 10.9 1.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG03305.1 - 0.025 13.7 0.3 0.048 12.7 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAG03305.1 - 0.051 13.2 0.5 0.051 13.2 0.5 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase TIP120 PF08623.10 OAG03306.1 - 1.5e-62 210.3 0.2 7e-61 204.9 0.0 3.2 4 0 0 4 4 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OAG03306.1 - 8.6e-11 42.1 17.2 0.06 13.7 0.0 8.7 8 2 2 10 10 9 4 HEAT repeats HEAT_EZ PF13513.6 OAG03306.1 - 2.4e-07 31.1 24.7 5.1 7.7 0.0 13.2 15 0 0 15 15 15 1 HEAT-like repeat MMS19_C PF12460.8 OAG03306.1 - 4.5e-07 29.3 13.3 0.0061 15.7 0.1 5.7 6 1 0 6 6 6 2 RNAPII transcription regulator C-terminal HEAT PF02985.22 OAG03306.1 - 7.8e-06 25.7 20.3 0.37 11.2 0.1 11.1 13 0 0 13 13 12 1 HEAT repeat MMS19_N PF14500.6 OAG03306.1 - 4.6e-05 23.1 6.3 0.25 10.9 0.1 5.1 5 1 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 OAG03306.1 - 0.00013 22.2 6.0 0.065 13.4 0.0 4.9 6 0 0 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 OAG03306.1 - 0.0013 18.8 3.1 1.4 9.0 0.0 4.8 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 OAG03306.1 - 0.0014 18.6 8.1 4.9 7.3 0.0 6.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RNA_pol_3_Rpc31 PF11705.8 OAG03306.1 - 0.0014 19.0 5.0 0.0035 17.6 5.0 1.7 2 0 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 UME PF08064.13 OAG03306.1 - 0.0023 17.8 2.0 3.1 7.8 0.0 4.3 4 0 0 4 4 4 1 UME (NUC010) domain Adaptin_N PF01602.20 OAG03306.1 - 0.0031 16.2 3.2 5.2 5.5 0.6 4.9 5 1 0 5 5 5 2 Adaptin N terminal region NBD_C PF17042.5 OAG03306.1 - 0.057 13.9 0.1 0.31 11.5 0.1 2.3 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain RRN3 PF05327.11 OAG03306.1 - 3 6.3 9.6 93 1.3 0.0 3.7 4 0 0 4 4 4 0 RNA polymerase I specific transcription initiation factor RRN3 Importin_rep_4 PF18808.1 OAG03306.1 - 5 7.5 10.1 2 8.7 0.0 4.8 4 0 0 4 4 3 0 Importin repeat PLAC8 PF04749.17 OAG03308.1 - 2.7e-19 70.0 9.8 3.9e-19 69.5 9.8 1.2 1 0 0 1 1 1 1 PLAC8 family DUF2263 PF10021.9 OAG03309.1 - 2.5e-16 60.4 0.0 6.4e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Unstab_antitox PF09720.10 OAG03309.1 - 0.021 14.9 1.9 0.053 13.6 1.1 2.0 2 0 0 2 2 2 0 Putative addiction module component NAD_binding_10 PF13460.6 OAG03311.1 - 7.2e-15 55.4 0.0 1.1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG03311.1 - 7.1e-11 42.1 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG03311.1 - 0.0099 15.3 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG03311.1 - 0.053 13.0 0.0 0.16 11.4 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG03311.1 - 0.15 11.0 0.0 0.33 9.9 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_61 PF03443.14 OAG03312.1 - 3.4e-44 151.2 0.2 4.4e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SWIB PF02201.18 OAG03314.1 - 0.058 13.3 0.2 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 SWIB/MDM2 domain GFA PF04828.14 OAG03315.1 - 3.7e-23 81.7 0.2 5.7e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 OAG03315.1 - 0.072 12.8 3.8 0.41 10.4 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain NMO PF03060.15 OAG03316.1 - 1.3e-46 159.6 0.5 3.9e-46 158.0 0.5 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG03316.1 - 5.9e-11 41.9 0.0 2.1e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG03316.1 - 2.5e-07 30.0 0.2 3.5e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OAG03316.1 - 0.0057 16.1 0.1 0.0099 15.4 0.1 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF1902 PF08972.11 OAG03316.1 - 0.028 14.4 0.1 0.69 9.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) Glu_synthase PF01645.17 OAG03316.1 - 0.035 13.2 2.4 0.083 12.0 0.2 2.4 2 1 1 3 3 3 0 Conserved region in glutamate synthase NanE PF04131.14 OAG03316.1 - 0.065 12.4 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase CFEM PF05730.11 OAG03317.1 - 4.6e-13 49.1 13.0 9.1e-13 48.1 13.0 1.5 1 0 0 1 1 1 1 CFEM domain DUF2534 PF10749.9 OAG03317.1 - 0.053 13.7 0.9 0.053 13.7 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2534) DUF998 PF06197.13 OAG03317.1 - 0.24 10.9 13.8 0.055 13.1 9.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF998) TIL PF01826.17 OAG03317.1 - 2.7 8.3 6.0 7.7 6.9 6.0 1.8 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain adh_short PF00106.25 OAG03318.1 - 2.6e-23 82.5 1.5 3.4e-23 82.1 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG03318.1 - 1e-18 67.8 2.4 1.2e-18 67.5 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG03318.1 - 3.1e-07 30.5 1.2 3.8e-07 30.2 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG03318.1 - 0.011 15.3 0.6 0.027 13.9 0.6 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DAO PF01266.24 OAG03319.1 - 2e-45 155.9 1.1 2.4e-45 155.6 1.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG03319.1 - 3.1e-05 23.3 0.0 6.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAG03319.1 - 9.7e-05 21.7 0.1 0.00038 19.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG03319.1 - 0.00011 22.3 0.2 0.00032 20.9 0.2 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 OAG03319.1 - 0.00066 18.6 0.0 0.00089 18.2 0.0 1.1 1 0 0 1 1 1 1 MCRA family Pyr_redox_3 PF13738.6 OAG03319.1 - 0.0015 17.8 0.0 0.0041 16.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG03319.1 - 0.025 13.8 0.1 0.051 12.8 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 OAG03319.1 - 0.027 13.6 0.9 0.16 11.0 0.9 2.0 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAG03319.1 - 0.089 12.8 0.1 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3530 PF12048.8 OAG03319.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DJ-1_PfpI PF01965.24 OAG03320.1 - 5.1e-19 68.7 0.0 8.2e-19 68.0 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 OAG03320.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I ACPS PF01648.20 OAG03321.1 - 8.8e-08 32.3 0.1 8.6e-07 29.1 0.1 2.4 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily WHAMM-JMY_N PF15920.5 OAG03321.1 - 0.048 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated SNO PF01174.19 OAG03322.1 - 1.2e-51 175.2 0.0 3.7e-43 147.6 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAG03322.1 - 3.6e-07 30.0 0.0 7.8e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 OAG03322.1 - 0.0032 17.3 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 OAG03322.1 - 0.076 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family DUF4741 PF15897.5 OAG03322.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) Peptidase_S51 PF03575.17 OAG03322.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 RRM_1 PF00076.22 OAG03323.1 - 5.1e-16 58.3 0.0 7.4e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCN5L1 PF06320.13 OAG03324.1 - 0.24 11.6 10.3 2.3 8.4 3.4 2.7 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) CENP-K PF11802.8 OAG03324.1 - 1 8.9 9.1 0.12 11.9 5.0 1.5 2 0 0 2 2 2 0 Centromere-associated protein K SKA2 PF16740.5 OAG03324.1 - 2.4 8.0 10.7 6.6 6.6 0.6 3.4 2 2 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Condensation PF00668.20 OAG03325.1 - 0.00015 20.6 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AATase PF07247.12 OAG03325.1 - 0.042 12.4 0.0 0.5 8.8 0.0 2.3 2 1 0 3 3 3 0 Alcohol acetyltransferase Abhydrolase_3 PF07859.13 OAG03326.1 - 1.3e-45 155.9 0.0 1.7e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG03326.1 - 1.7e-10 40.4 0.0 1e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 OAG03326.1 - 0.00054 20.6 0.8 0.0015 19.2 0.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG03326.1 - 0.0019 17.7 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG03326.1 - 0.017 14.4 0.0 0.17 11.1 0.0 2.0 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAG03326.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 OAG03326.1 - 0.039 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DIT1_PvcA PF05141.12 OAG03327.1 - 1e-90 304.0 0.0 1.8e-90 303.2 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC_tran PF00005.27 OAG03327.1 - 1.5e-12 48.2 0.2 3.9e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OAG03327.1 - 0.00029 20.8 0.1 0.0007 19.5 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OAG03327.1 - 0.0021 18.5 0.6 0.007 16.8 0.5 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 OAG03327.1 - 0.0034 17.0 1.0 0.023 14.3 1.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG03327.1 - 0.024 14.4 0.2 0.053 13.3 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG03327.1 - 0.074 13.3 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG03327.1 - 0.14 12.3 0.1 0.7 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG03327.1 - 0.17 12.4 0.0 0.44 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 OAG03329.1 - 4.1e-24 84.9 0.0 6.9e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 OAG03329.1 - 3.6e-09 35.8 0.0 5.9e-07 28.5 0.0 2.7 2 1 0 2 2 2 1 Transferase family PP-binding PF00550.25 OAG03329.1 - 1.7e-06 28.3 0.1 7.9e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site MFS_1 PF07690.16 OAG03330.1 - 9e-39 133.4 52.6 8.2e-38 130.2 51.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG03330.1 - 6.2e-11 41.4 17.1 1.4e-10 40.3 17.1 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG03330.1 - 2.3e-10 39.9 23.5 1.1e-09 37.7 11.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Phage_holin_2_4 PF16082.5 OAG03330.1 - 0.86 9.4 3.3 4.2 7.2 0.0 2.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4153 PF13687.6 OAG03330.1 - 8.1 6.0 16.2 0.027 14.1 4.9 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4153) MFS_1 PF07690.16 OAG03331.1 - 1.5e-18 66.9 60.2 1.5e-15 57.0 27.4 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.12 OAG03331.1 - 0.95 9.7 7.2 0.097 12.8 0.9 2.7 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 DJ-1_PfpI PF01965.24 OAG03332.1 - 2.9e-12 46.7 0.0 3.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Abhydrolase_1 PF00561.20 OAG03335.1 - 4.8e-21 75.6 0.1 7.9e-17 61.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG03335.1 - 4.2e-17 63.5 8.2 3.9e-16 60.3 8.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG03335.1 - 3.3e-11 42.9 0.0 1.6e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG03335.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 OAG03335.1 - 0.046 13.2 0.2 0.19 11.2 0.2 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 OAG03335.1 - 0.052 12.2 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF3246 PF11596.8 OAG03336.1 - 0.0084 15.6 0.0 0.0084 15.6 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3246) Polyketide_cyc2 PF10604.9 OAG03337.1 - 1.6e-07 31.7 0.0 1.9e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ADH_zinc_N_2 PF13602.6 OAG03338.1 - 5.6e-14 53.3 0.0 9.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG03338.1 - 1.9e-10 40.8 0.1 4.5e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG03338.1 - 2e-06 27.6 1.8 0.0028 17.5 0.1 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain DUF1565 PF07602.11 OAG03338.1 - 0.12 11.7 0.0 0.4 10.0 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1565) NUP PF06516.11 OAG03341.1 - 1.7e-56 191.7 2.3 3e-30 105.5 1.1 3.6 1 1 1 2 2 2 2 Purine nucleoside permease (NUP) Beta-lactamase PF00144.24 OAG03342.1 - 7.4e-34 117.5 0.1 1e-33 117.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.18 OAG03343.1 - 1.1e-08 34.5 0.1 1.9e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03343.1 - 1.9e-06 27.9 10.2 4.5e-06 26.7 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG03344.1 - 7.6e-21 74.5 0.1 1.2e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG03344.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG03344.1 - 2e-08 34.4 0.0 3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG03344.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG03344.1 - 0.027 13.6 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_35 PF01301.19 OAG03345.1 - 1.4e-83 281.1 0.9 1.9e-83 280.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAG03345.1 - 4.7e-09 36.8 0.3 4e-07 30.6 0.2 2.5 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 OAG03345.1 - 4.6e-07 29.5 0.2 1.7e-06 27.7 0.2 1.7 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_14 PF01373.17 OAG03345.1 - 0.0058 15.6 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 DUF4434 PF14488.6 OAG03345.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) BTB PF00651.31 OAG03346.1 - 2e-05 24.8 0.0 9.9e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain DUF4379 PF14311.6 OAG03346.1 - 0.0049 17.2 13.9 0.017 15.4 4.0 3.1 2 0 0 2 2 2 2 Probable Zinc-ribbon domain DEAD PF00270.29 OAG03347.1 - 7e-35 120.4 0.3 1.2e-34 119.7 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG03347.1 - 3.4e-28 98.2 0.0 1.3e-27 96.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG03347.1 - 0.0034 17.4 0.5 0.027 14.5 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAG03347.1 - 0.013 15.9 0.1 0.043 14.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain Translin PF01997.16 OAG03348.1 - 6.7e-48 163.4 0.0 7.8e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Translin family vATP-synt_E PF01991.18 OAG03348.1 - 0.029 13.8 1.2 0.084 12.3 0.2 1.9 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit PLU-1 PF08429.11 OAG03348.1 - 0.062 12.5 0.2 0.086 12.0 0.2 1.1 1 0 0 1 1 1 0 PLU-1-like protein PIG-F PF06699.11 OAG03349.1 - 1.4e-64 217.6 6.6 1.6e-64 217.4 6.6 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4396 PF14342.6 OAG03349.1 - 0.031 14.6 0.6 3.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Gly-zipper_Omp PF13488.6 OAG03349.1 - 0.054 13.5 9.2 0.8 9.7 1.1 2.7 2 0 0 2 2 2 0 Glycine zipper Romo1 PF10247.9 OAG03349.1 - 1.8 9.0 7.0 14 6.1 0.2 2.5 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 CRF-BP PF05428.11 OAG03351.1 - 0.028 13.2 0.0 0.03 13.1 0.0 1.0 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Sugar_tr PF00083.24 OAG03352.1 - 3.5e-76 256.9 17.7 4e-76 256.7 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG03352.1 - 2.1e-24 86.1 18.2 2.1e-24 86.1 18.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG03352.1 - 4.7e-08 32.0 13.0 9.1e-05 21.2 3.1 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 OAG03352.1 - 1.8e-05 23.4 0.9 1.8e-05 23.4 0.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG03352.1 - 0.79 7.9 12.4 0.011 14.1 1.3 2.6 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DJ-1_PfpI PF01965.24 OAG03353.1 - 3.5e-09 36.7 0.0 6.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Sugar_tr PF00083.24 OAG03354.1 - 8.9e-96 321.5 26.1 1.1e-95 321.2 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG03354.1 - 1.5e-25 89.8 34.0 7.3e-25 87.6 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 OAG03355.1 - 1.2e-19 70.5 0.9 1.9e-19 69.8 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG03355.1 - 1.1e-09 38.2 0.1 2.3e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like 2-Hacid_dh_C PF02826.19 OAG03357.1 - 2.6e-60 202.8 0.0 3.6e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG03357.1 - 1.7e-21 76.3 0.0 2.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 OAG03357.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 OAG03357.1 - 0.0097 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ShlB PF03865.13 OAG03357.1 - 0.032 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB AdoHcyase_NAD PF00670.21 OAG03357.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain p450 PF00067.22 OAG03358.1 - 3e-35 121.9 0.0 3.8e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 OAG03359.1 - 3.6e-124 415.1 23.6 4.2e-124 414.9 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG03359.1 - 2.3e-25 89.3 20.8 2.3e-25 89.3 20.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Barttin PF15462.6 OAG03359.1 - 0.044 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF2613 PF11021.8 OAG03360.1 - 0.0026 17.8 0.0 0.0075 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) SpoU_methylase PF00588.19 OAG03361.1 - 1.4e-24 86.9 0.0 5.7e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 SpoU rRNA Methylase family Kinesin PF00225.23 OAG03362.1 - 2.5e-113 378.4 0.0 3.3e-113 378.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG03362.1 - 1e-26 93.7 0.0 2.2e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding GAS PF13851.6 OAG03362.1 - 0.011 15.1 4.4 0.019 14.3 4.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OAG03362.1 - 0.071 12.0 6.9 0.12 11.2 6.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Shugoshin_N PF07558.11 OAG03362.1 - 0.075 12.9 0.2 0.23 11.4 0.2 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Golgin_A5 PF09787.9 OAG03362.1 - 0.11 12.0 8.5 0.029 13.8 4.2 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF87 PF01935.17 OAG03362.1 - 0.24 11.5 2.0 0.63 10.1 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain TT_ORF2 PF02957.15 OAG03362.1 - 0.28 12.1 1.3 0.68 10.9 1.3 1.7 1 0 0 1 1 1 0 TT viral ORF2 Dynein_C PF18199.1 OAG03362.1 - 0.36 10.0 1.9 7.7 5.6 1.2 2.2 2 0 0 2 2 2 0 Dynein heavy chain C-terminal domain DivIC PF04977.15 OAG03362.1 - 2.8 7.8 6.4 3.8 7.4 0.0 3.2 2 1 0 3 3 3 0 Septum formation initiator Vps16_N PF04841.13 OAG03363.1 - 4.4e-98 328.7 0.0 6.6e-98 328.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OAG03363.1 - 6.2e-84 281.8 0.0 1.4e-83 280.7 0.0 1.5 1 1 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 OAG03363.1 - 0.00028 21.1 0.0 0.26 11.6 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain ECH_2 PF16113.5 OAG03364.1 - 1.4e-125 419.2 0.0 1.9e-125 418.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OAG03364.1 - 1.9e-29 102.7 0.0 1.9e-27 96.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF3258 PF11646.8 OAG03364.1 - 0.045 13.9 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF3258 PqqD PF05402.12 OAG03364.1 - 0.056 13.8 0.3 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) GTP_EFTU PF00009.27 OAG03365.1 - 7.6e-58 195.3 0.2 9.9e-58 194.9 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG03365.1 - 3e-25 88.7 0.0 5.8e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG03365.1 - 1.2e-16 60.8 1.5 3.1e-16 59.5 1.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG03365.1 - 8.3e-06 25.9 0.1 1.7e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG03365.1 - 0.00034 20.6 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 OAG03365.1 - 0.0082 15.8 0.6 0.055 13.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAG03365.1 - 0.012 15.4 0.4 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OAG03365.1 - 0.093 12.1 0.2 0.32 10.3 0.2 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2917 PF11142.8 OAG03365.1 - 0.096 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) APH PF01636.23 OAG03366.1 - 8e-11 42.3 0.1 1.3e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG03366.1 - 0.00057 19.3 0.0 0.00088 18.7 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 OAG03366.1 - 0.00072 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 OAG03366.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MFS_1 PF07690.16 OAG03369.1 - 7.1e-38 130.4 21.2 7.1e-38 130.4 21.2 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03369.1 - 1.2e-11 44.2 2.0 1.2e-11 44.2 2.0 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 OAG03369.1 - 0.0011 17.5 0.1 0.0011 17.5 0.1 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Ammonium_transp PF00909.21 OAG03369.1 - 0.0051 15.6 2.7 0.0051 15.6 2.7 2.1 2 0 0 2 2 2 1 Ammonium Transporter Family MFS_1_like PF12832.7 OAG03369.1 - 4 6.2 16.7 0.061 12.2 4.1 2.7 3 0 0 3 3 3 0 MFS_1 like family Na_Ca_ex PF01699.24 OAG03370.1 - 1.5e-31 109.4 32.8 5.9e-17 62.0 10.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Topo_Zn_Ribbon PF08272.11 OAG03371.1 - 0.16 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like MANEC PF07502.14 OAG03374.1 - 0.004 17.4 1.1 0.0087 16.3 1.1 1.5 1 0 0 1 1 1 1 MANEC domain PAN_1 PF00024.26 OAG03374.1 - 0.021 14.8 0.3 0.038 14.0 0.3 1.4 1 0 0 1 1 1 0 PAN domain Sporozoite_P67 PF05642.11 OAG03374.1 - 2.9 5.8 6.2 3.3 5.7 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_5 PF13857.6 OAG03375.1 - 1.3e-06 28.6 0.6 2.7e-06 27.5 0.6 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG03375.1 - 0.0004 20.9 0.3 0.0016 18.9 0.3 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG03375.1 - 0.0016 18.7 0.4 0.02 15.4 0.2 2.9 1 1 1 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OAG03375.1 - 0.0021 18.6 3.8 0.046 14.3 0.3 2.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OAG03377.1 - 6.2e-20 71.6 0.0 6.9e-07 29.8 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG03377.1 - 1.8e-17 63.2 0.4 0.00059 20.1 0.0 6.3 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG03377.1 - 2e-17 63.3 0.0 4.1e-06 27.2 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG03377.1 - 1.6e-13 49.4 0.2 0.67 10.7 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OAG03377.1 - 2.8e-13 49.7 4.0 0.0079 16.6 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Tautomerase_2 PF14552.6 OAG03378.1 - 0.15 12.2 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Tautomerase enzyme FMO-like PF00743.19 OAG03379.1 - 2.6e-20 72.4 0.0 3.4e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG03379.1 - 4.7e-15 55.6 0.0 4e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG03379.1 - 8.4e-14 51.5 0.0 1.8e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG03379.1 - 9.6e-12 44.7 0.0 3.2e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG03379.1 - 1.9e-09 37.6 0.2 2.3e-07 30.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG03379.1 - 0.0032 17.5 3.8 7 6.6 0.2 4.5 4 2 1 5 5 5 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG03379.1 - 0.0046 17.5 0.1 2 9.0 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG03379.1 - 0.015 14.4 0.0 0.091 11.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 OAG03379.1 - 0.024 14.2 9.2 5.5 6.5 0.1 5.1 2 2 4 6 6 6 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG03379.1 - 0.13 11.3 0.0 2 7.4 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAG03379.1 - 0.19 10.9 3.2 1.1 8.5 0.0 2.9 2 2 2 4 4 4 0 FAD binding domain Zn_clus PF00172.18 OAG03381.1 - 1.1e-08 35.0 10.8 2.1e-08 34.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG03381.1 - 2.4e-07 29.9 0.2 3.5e-07 29.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vac7 PF12751.7 OAG03383.1 - 7.6e-128 427.2 8.3 7.6e-128 427.2 8.3 1.5 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Ist1 PF03398.14 OAG03386.1 - 5.4e-56 189.0 0.3 7.1e-56 188.6 0.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway MutS_V PF00488.21 OAG03387.1 - 3.9e-83 278.1 0.4 7.6e-83 277.2 0.4 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG03387.1 - 3.2e-36 125.4 0.4 8.1e-36 124.0 0.4 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 OAG03387.1 - 1.5e-20 73.9 0.0 4.7e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAG03387.1 - 1.3e-18 67.1 2.1 1.3e-18 67.1 0.3 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 OAG03387.1 - 9.6e-14 51.6 0.0 3.8e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MbeD_MobD PF04899.12 OAG03387.1 - 0.0034 17.5 0.3 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 MbeD/MobD like IFN-gamma PF00714.17 OAG03387.1 - 0.014 15.2 0.2 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 Interferon gamma AAA_27 PF13514.6 OAG03387.1 - 0.069 12.7 0.0 0.26 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DLH PF01738.18 OAG03389.1 - 5.1e-33 114.5 0.0 5.8e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG03389.1 - 0.038 13.4 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Cir_N PF10197.9 OAG03390.1 - 9.5e-06 25.7 0.4 9.5e-06 25.7 0.4 4.8 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PRP1_N PF06424.12 OAG03392.1 - 9.7e-51 172.1 6.8 9.7e-51 172.1 6.8 1.9 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 OAG03392.1 - 1.5e-28 97.0 11.0 0.067 14.0 0.0 12.9 5 3 6 12 12 11 8 Tetratricopeptide repeat TPR_19 PF14559.6 OAG03392.1 - 3.2e-23 82.0 5.5 0.022 15.3 0.0 10.4 6 2 5 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 OAG03392.1 - 1.1e-10 42.0 2.6 0.16 12.6 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG03392.1 - 2.5e-10 39.6 4.7 0.061 13.5 0.0 9.7 10 1 1 11 11 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG03392.1 - 1.4e-07 31.0 0.1 0.41 10.5 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG03392.1 - 4.2e-06 26.5 0.2 4.1 7.8 0.1 6.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG03392.1 - 4.4e-05 23.6 0.0 1.4e+02 3.2 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG03392.1 - 0.00011 21.8 0.6 4.1 7.2 0.0 5.7 6 0 0 6 6 6 1 TPR repeat NARP1 PF12569.8 OAG03392.1 - 0.00035 19.6 9.8 2.1 7.1 0.1 6.6 4 2 2 7 7 7 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 OAG03392.1 - 0.0018 18.2 0.1 1.1 9.4 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat GP63 PF17471.2 OAG03392.1 - 0.0069 16.5 3.2 0.077 13.2 0.2 3.4 3 0 0 3 3 2 1 Gene product 63 TPR_MalT PF17874.1 OAG03392.1 - 0.012 15.0 16.5 0.02 14.3 4.0 4.4 2 1 0 3 3 3 0 MalT-like TPR region Suf PF05843.14 OAG03392.1 - 0.02 14.9 0.2 7.5 6.4 0.0 4.1 4 1 1 5 5 5 0 Suppressor of forked protein (Suf) Fer4_13 PF13370.6 OAG03392.1 - 0.021 15.3 0.4 31 5.2 0.0 4.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I NRDE-2 PF08424.10 OAG03392.1 - 0.026 13.7 15.1 0.42 9.7 0.1 4.9 4 2 1 5 5 5 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 OAG03392.1 - 0.069 13.8 9.5 13 6.7 0.0 7.7 8 1 1 9 9 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG03392.1 - 0.073 13.2 0.2 27 5.0 0.0 3.8 2 2 1 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 OAG03392.1 - 0.099 11.6 3.2 37 3.1 0.0 3.9 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 OAG03392.1 - 0.15 12.4 9.9 2.7 8.3 0.5 5.9 5 1 2 8 8 6 0 Tetratricopeptide repeat SNAP PF14938.6 OAG03392.1 - 0.16 11.4 2.3 1.6 8.1 0.2 3.3 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP YL1 PF05764.13 OAG03392.1 - 0.43 10.7 11.1 1.6 8.8 11.1 2.0 1 0 0 1 1 1 0 YL1 nuclear protein zf-CCCH_4 PF18044.1 OAG03393.1 - 1.4e-08 34.3 12.5 9.6e-06 25.3 4.6 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 OAG03393.1 - 2.2e-08 33.8 11.8 3.1e-05 23.8 2.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OAG03393.1 - 2.6e-07 31.3 7.7 0.00079 20.1 0.8 2.4 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 OAG03393.1 - 5.1e-07 29.5 18.9 0.00042 20.3 3.6 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAG03393.1 - 6.2e-05 23.2 1.4 0.00012 22.2 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 OAG03393.1 - 0.2 12.2 15.3 0.82 10.2 2.4 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger ANAPC4_WD40 PF12894.7 OAG03396.1 - 2.1e-09 37.5 0.1 0.003 17.8 0.0 5.3 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG03396.1 - 2.8e-05 24.8 2.6 4.7 8.2 0.1 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 OAG03396.1 - 0.062 13.3 0.0 5.2 7.1 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Acetyltransf_10 PF13673.7 OAG03397.1 - 1.2e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG03397.1 - 1.5e-06 28.5 0.0 3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG03397.1 - 1.6e-06 28.4 0.0 3.1e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAG03397.1 - 0.00089 19.3 0.1 0.082 13.0 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain CH PF00307.31 OAG03399.1 - 9e-74 244.7 0.0 1.7e-21 76.4 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 OAG03399.1 - 3.7e-06 27.3 2.2 1.5e-05 25.4 0.4 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OAG03399.1 - 0.00049 19.8 0.5 0.022 14.6 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OAG03399.1 - 0.0011 18.3 1.0 0.52 10.0 0.1 3.5 3 0 0 3 3 3 1 EF hand CAMSAP_CH PF11971.8 OAG03399.1 - 0.0019 18.0 0.0 0.26 11.2 0.0 3.2 3 0 0 3 3 3 1 CAMSAP CH domain KilA-N PF04383.13 OAG03401.1 - 7.1e-05 22.6 0.0 0.00096 19.0 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain p450 PF00067.22 OAG03403.1 - 7e-52 176.7 0.0 1.3e-51 175.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF5387 PF17361.2 OAG03403.1 - 0.0087 15.8 0.0 0.029 14.0 0.0 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF5387) WSC PF01822.19 OAG03404.1 - 8.4e-19 67.5 13.0 5.6e-10 39.3 7.3 2.2 2 0 0 2 2 2 2 WSC domain WSC PF01822.19 OAG03405.1 - 1.6e-61 204.5 53.3 1.6e-17 63.5 10.2 4.6 4 0 0 4 4 4 4 WSC domain PQQ_3 PF13570.6 OAG03405.1 - 0.00023 21.5 12.0 0.13 12.8 0.0 5.5 5 0 0 5 5 5 2 PQQ-like domain DUF1834 PF08873.11 OAG03405.1 - 0.099 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) Toxin_3 PF00537.18 OAG03405.1 - 0.34 11.1 0.0 0.34 11.1 0.0 6.3 8 0 0 8 8 8 0 Scorpion toxin-like domain PQQ PF01011.21 OAG03405.1 - 1.7 8.7 10.9 8.7 6.5 0.0 4.8 5 0 0 5 5 5 0 PQQ enzyme repeat ATG7_N PF16420.5 OAG03406.1 - 2.2e-112 375.6 0.0 3e-112 375.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 OAG03406.1 - 1.9e-43 148.6 0.0 3e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Cu-oxidase_3 PF07732.15 OAG03408.1 - 3.8e-40 136.6 4.0 6.1e-37 126.3 0.6 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG03408.1 - 1.4e-38 131.7 14.6 8.3e-36 122.7 1.0 4.4 3 2 1 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.22 OAG03408.1 - 5e-30 104.7 0.8 1.2e-29 103.5 0.4 1.9 2 0 0 2 2 2 1 Multicopper oxidase Patatin PF01734.22 OAG03410.1 - 6.2e-23 82.0 0.1 7.4e-22 78.5 0.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase Acetyltransf_3 PF13302.7 OAG03411.1 - 3.4e-29 102.3 0.0 4e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG03411.1 - 0.0011 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Rft-1 PF04506.13 OAG03412.1 - 3.6e-145 484.6 12.2 4.1e-145 484.4 12.2 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 OAG03412.1 - 8.3e-06 25.2 10.9 0.00053 19.3 10.9 3.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Ppx-GppA PF02541.16 OAG03413.1 - 7.6e-46 156.8 0.0 1.3e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 OAG03413.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family ELFV_dehydrog PF00208.21 OAG03414.1 - 4e-65 219.9 0.0 6.8e-65 219.2 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OAG03414.1 - 7.5e-19 66.9 0.1 3.6e-13 48.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 OAG03414.1 - 0.031 14.1 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ATP_bind_1 PF03029.17 OAG03416.1 - 2.7e-77 259.8 0.0 3.8e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAG03416.1 - 1.8e-05 24.6 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 OAG03416.1 - 0.00037 20.5 0.0 0.0009 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAG03416.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG03416.1 - 0.0021 18.3 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG03416.1 - 0.0051 17.2 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 OAG03416.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 OAG03416.1 - 0.014 14.7 0.0 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 OAG03416.1 - 0.014 15.7 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 OAG03416.1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 OAG03416.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OAG03416.1 - 0.017 14.6 0.1 0.067 12.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 OAG03416.1 - 0.019 15.5 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG03416.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAG03416.1 - 0.036 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 OAG03416.1 - 0.038 13.7 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG03416.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.17 OAG03416.1 - 0.056 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RsgA_GTPase PF03193.16 OAG03416.1 - 0.075 12.9 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase KAP_NTPase PF07693.14 OAG03416.1 - 0.089 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain GTP_EFTU PF00009.27 OAG03416.1 - 0.11 12.1 0.0 7.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Sigma54_activat PF00158.26 OAG03416.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 OAG03416.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 OAG03416.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain cobW PF02492.19 OAG03416.1 - 0.17 11.5 0.0 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OAG03416.1 - 0.18 11.7 0.0 0.63 9.9 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 OAG03416.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_19 PF13245.6 OAG03416.1 - 0.2 12.0 0.0 1.4 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain S-AdoMet_synt_C PF02773.16 OAG03417.1 - 2.8e-66 221.7 0.6 1.5e-65 219.3 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OAG03417.1 - 9.3e-46 155.0 0.0 2e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OAG03417.1 - 3.1e-44 149.7 0.7 8.3e-44 148.3 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain WW PF00397.26 OAG03418.1 - 0.0026 17.8 0.1 0.0026 17.8 0.1 2.0 2 0 0 2 2 2 1 WW domain CDC45 PF02724.14 OAG03418.1 - 1.4 7.1 4.7 1.9 6.7 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.8 OAG03419.1 - 5.2 7.2 8.2 1.6 8.8 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) Malic_M PF03949.15 OAG03420.1 - 8.9e-93 310.3 0.0 1.1e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAG03420.1 - 7.1e-61 205.2 0.0 1.1e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.6 OAG03422.1 - 2.9e-07 30.7 2.7 3.5e-06 27.2 0.1 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) AbiH PF14253.6 OAG03422.1 - 0.00092 19.2 3.7 0.0016 18.4 3.7 1.3 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH Tricorn_C1 PF14684.6 OAG03422.1 - 0.041 13.9 0.1 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease C1 domain DUF4208 PF13907.6 OAG03422.1 - 0.055 13.9 1.7 4.2 7.9 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Phage_GPL PF05926.11 OAG03422.1 - 0.11 12.5 0.2 26 4.8 0.0 2.8 2 0 0 2 2 2 0 Phage head completion protein (GPL) ABC_tran_CTD PF16326.5 OAG03422.1 - 0.13 12.5 0.5 2.9 8.2 0.0 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain Kinesin PF00225.23 OAG03423.1 - 1.2e-82 277.5 0.3 2e-82 276.8 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG03423.1 - 7.6e-20 71.4 0.0 1.9e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 OAG03423.1 - 0.0001 22.0 0.3 0.00098 18.9 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAG03423.1 - 0.026 15.1 3.6 0.19 12.3 0.4 2.8 2 1 1 3 3 3 0 Helix-hairpin-helix domain Trimer_CC PF08954.11 OAG03423.1 - 0.047 13.2 2.0 0.064 12.8 0.2 2.3 2 0 0 2 2 2 0 Trimerisation motif HHH_3 PF12836.7 OAG03423.1 - 0.085 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ribosomal_L16 PF00252.18 OAG03424.1 - 2.9e-45 153.5 0.1 3.7e-45 153.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 OAG03425.1 - 4.2e-25 87.3 0.0 4.8e-25 87.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MCM PF00493.23 OAG03426.1 - 9.5e-103 342.1 0.1 1.5e-102 341.4 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG03426.1 - 1e-39 135.3 0.1 9.4e-39 132.1 0.0 2.2 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 OAG03426.1 - 1.4e-25 89.5 0.6 4.2e-25 88.0 0.6 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 OAG03426.1 - 2.2e-22 80.0 26.8 2.2e-22 80.0 26.8 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 OAG03426.1 - 3.2e-14 53.4 0.1 7.8e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG03426.1 - 9.9e-09 34.9 0.2 1.9e-06 27.4 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG03426.1 - 4.2e-06 26.8 0.0 1.2e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAG03426.1 - 0.00026 20.9 0.1 0.0035 17.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG03426.1 - 0.0013 18.4 0.2 0.0095 15.7 0.2 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 OAG03426.1 - 0.0089 15.8 0.7 0.019 14.7 0.7 1.5 1 0 0 1 1 1 1 AAA domain DUF3113 PF11310.8 OAG03426.1 - 0.18 11.8 2.1 0.61 10.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3113) zf-UBR PF02207.20 OAG03427.1 - 1.3e-13 50.9 3.8 1.3e-13 50.9 3.8 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) APG9 PF04109.16 OAG03428.1 - 7.6e-176 585.8 7.3 9e-176 585.6 7.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.11 OAG03429.1 - 7.1e-221 734.8 4.8 8e-221 734.6 4.8 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF948 PF06103.11 OAG03429.1 - 0.0026 18.0 1.1 0.68 10.2 0.0 3.7 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) Cep57_CLD PF14073.6 OAG03429.1 - 0.024 14.7 0.8 0.058 13.4 0.8 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF5089 PF17002.5 OAG03429.1 - 0.027 14.3 0.3 0.064 13.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) HsbA PF12296.8 OAG03429.1 - 0.028 14.9 0.9 0.24 11.8 0.1 2.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Hydrolase_3 PF08282.12 OAG03429.1 - 0.08 12.7 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1043 PF06295.12 OAG03429.1 - 0.081 12.9 1.0 34 4.5 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) COG2 PF06148.11 OAG03429.1 - 0.091 12.8 0.6 0.62 10.2 0.2 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BolA PF01722.18 OAG03430.1 - 2.5e-18 66.1 0.0 1.6e-17 63.6 0.0 2.1 2 1 0 2 2 2 1 BolA-like protein NIF3 PF01784.18 OAG03431.1 - 2.6e-59 200.8 0.0 3.3e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RPA_interact_M PF14767.6 OAG03431.1 - 0.11 13.1 0.3 0.23 12.0 0.3 1.5 1 0 0 1 1 1 0 Replication protein A interacting middle TFIID_20kDa PF03847.13 OAG03432.1 - 5e-23 81.4 0.1 9.2e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DENN PF02141.21 OAG03433.1 - 0.00053 20.0 0.5 0.013 15.5 0.5 2.4 1 1 0 1 1 1 1 DENN (AEX-3) domain Vac14_Fig4_bd PF11916.8 OAG03434.1 - 5.8e-82 273.7 7.4 5.8e-82 273.7 7.4 2.2 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OAG03434.1 - 1.5e-46 156.9 0.0 1.5e-42 144.1 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAG03434.1 - 1.3e-07 31.3 0.3 0.002 18.2 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 OAG03434.1 - 3.1e-07 30.8 0.7 0.025 15.1 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 OAG03434.1 - 8.8e-07 29.1 2.4 0.015 15.4 0.4 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG03434.1 - 6.9e-06 26.4 0.2 0.18 12.2 0.0 4.9 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.23 OAG03434.1 - 0.0032 17.4 0.0 16 5.7 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Vma12 PF11712.8 OAG03435.1 - 2.7e-43 147.4 0.0 5.5e-43 146.4 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TRAPPC9-Trs120 PF08626.11 OAG03435.1 - 0.21 8.9 0.0 0.28 8.5 0.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit polyprenyl_synt PF00348.17 OAG03436.1 - 1.8e-71 240.2 0.0 4.2e-71 239.0 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase WD40 PF00400.32 OAG03437.1 - 3.9e-62 204.7 13.7 1.9e-12 47.5 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG03437.1 - 1.9e-21 76.1 0.3 0.0012 19.0 0.0 6.1 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG03437.1 - 7.1e-08 31.8 0.2 0.4 9.6 0.0 4.8 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG03437.1 - 7.6e-07 29.2 0.0 0.001 19.0 0.0 3.4 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OAG03437.1 - 1.6e-05 24.7 1.3 1.4 8.9 0.2 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OAG03437.1 - 2.3e-05 23.2 4.9 0.019 13.7 0.1 4.4 3 2 2 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG03437.1 - 0.00021 20.7 0.0 0.0011 18.4 0.0 2.2 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 OAG03437.1 - 0.0028 16.1 0.0 0.12 10.7 0.0 2.1 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF1513 PF07433.11 OAG03437.1 - 0.0029 16.7 0.3 9.6 5.2 0.0 3.4 1 1 3 4 4 4 2 Protein of unknown function (DUF1513) VID27 PF08553.10 OAG03437.1 - 0.04 13.0 0.0 4.4 6.2 0.0 3.0 2 1 2 4 4 4 0 VID27 C-terminal WD40-like domain IKI3 PF04762.12 OAG03437.1 - 0.16 9.9 0.0 0.26 9.2 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Exo_endo_phos PF03372.23 OAG03438.1 - 2.7e-17 63.1 0.1 4.2e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.9 OAG03438.1 - 0.009 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Luciferase catalytic domain DUF1275 PF06912.11 OAG03438.1 - 0.056 13.4 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Glyco_hydro_61 PF03443.14 OAG03439.1 - 2.3e-28 99.6 0.0 3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 OAG03439.1 - 0.089 13.3 0.2 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 MG2 domain MFMR_assoc PF16596.5 OAG03440.1 - 0.11 13.0 0.3 0.11 13.0 0.3 3.1 3 0 0 3 3 3 0 Disordered region downstream of MFMR Vps62 PF06101.11 OAG03441.1 - 1e-10 40.6 0.2 1.7e-10 39.9 0.2 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 PQ-loop PF04193.14 OAG03444.1 - 1.7e-25 88.6 2.5 8e-18 64.0 0.7 2.9 2 0 0 2 2 2 2 PQ loop repeat Peptidase_U4 PF03419.13 OAG03444.1 - 0.067 12.5 9.5 0.031 13.6 6.5 1.8 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Phage_holin_3_1 PF05106.12 OAG03444.1 - 0.18 12.3 2.1 0.29 11.6 1.6 1.6 1 1 0 1 1 1 0 Phage holin family (Lysis protein S) SLATT_1 PF18181.1 OAG03444.1 - 0.5 10.3 2.9 0.84 9.6 2.0 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Evr1_Alr PF04777.13 OAG03445.1 - 3e-30 104.6 4.4 4.2e-30 104.2 3.8 1.5 2 0 0 2 2 2 1 Erv1 / Alr family TetR_C_21 PF17926.1 OAG03446.1 - 0.015 15.5 0.4 0.023 14.8 0.4 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 OAG03447.1 - 3e-67 226.8 0.0 3.6e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03447.1 - 7.3e-32 110.7 0.0 9.3e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG03447.1 - 0.00024 20.5 0.3 0.00038 19.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG03447.1 - 0.0028 16.7 0.2 0.0041 16.1 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAG03447.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG03447.1 - 0.018 15.0 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAG03447.1 - 0.033 13.2 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.29 OAG03448.1 - 6.9e-49 166.0 0.0 1.2e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG03448.1 - 1e-30 106.3 0.0 7.3e-28 97.1 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAG03448.1 - 5.5e-08 33.0 0.0 1.9e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OAG03448.1 - 0.00074 18.4 0.0 0.014 14.2 0.0 2.4 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Borrelia_P83 PF05262.11 OAG03448.1 - 1.2 7.5 22.0 1.7 7.1 22.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PAP1 PF08601.10 OAG03448.1 - 1.7 8.3 19.4 2.7 7.6 19.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Sas10_Utp3 PF04000.15 OAG03449.1 - 6e-19 68.5 1.4 1.7e-18 67.0 1.4 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RabGAP-TBC PF00566.18 OAG03450.1 - 1.7e-51 174.9 0.0 2.8e-49 167.7 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain eIF3_subunit PF08597.10 OAG03451.1 - 0.12 12.3 1.5 0.15 12.0 1.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PBP_N PF17093.5 OAG03451.1 - 1.9 8.7 8.8 0.95 9.7 5.2 1.8 1 1 1 2 2 2 0 Penicillin-binding protein N-terminus GPI PF06560.11 OAG03453.1 - 0.047 13.0 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) RRM_1 PF00076.22 OAG03454.1 - 4.8e-35 119.2 0.1 1.8e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG03454.1 - 4.1e-13 49.3 0.1 2.7e-05 24.2 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OAG03454.1 - 0.00033 20.7 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 OAG03454.1 - 0.0011 18.9 0.0 0.88 9.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 OAG03454.1 - 0.033 13.9 0.5 3 7.6 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain TMEM156 PF15106.6 OAG03454.1 - 0.035 13.6 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 TMEM156 protein family Mpt_N PF09176.11 OAG03454.1 - 0.092 12.9 0.3 20 5.4 0.0 2.6 3 0 0 3 3 3 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal DWNN PF08783.11 OAG03455.1 - 8.5e-26 90.1 0.0 1.6e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 OAG03455.1 - 1.3e-09 37.7 5.7 2.4e-09 36.9 5.7 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 OAG03455.1 - 0.00015 21.8 0.0 0.00046 20.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 OAG03455.1 - 0.0041 16.9 8.6 0.0041 16.9 8.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OAG03455.1 - 0.0064 16.3 3.1 0.012 15.4 3.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCHC_3 PF13917.6 OAG03455.1 - 0.0088 16.0 0.1 0.023 14.6 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 OAG03455.1 - 0.021 13.2 8.1 0.038 12.3 8.1 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-RING_4 PF14570.6 OAG03455.1 - 0.12 12.2 5.1 0.35 10.7 5.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OAG03455.1 - 0.14 12.5 6.3 0.34 11.3 6.3 1.7 1 0 0 1 1 1 0 Ring finger domain Spore_III_AF PF09581.10 OAG03455.1 - 0.34 10.9 4.9 4 7.4 0.1 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) zf-RING_UBOX PF13445.6 OAG03455.1 - 0.51 10.4 6.2 1.1 9.4 6.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Ndc1_Nup PF09531.10 OAG03455.1 - 0.76 8.4 14.3 0.14 10.8 9.3 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 OAG03455.1 - 5.6 5.7 8.6 8.2 5.1 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1272 PF06906.11 OAG03455.1 - 5.9 7.1 8.6 0.38 10.9 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.6 OAG03455.1 - 6.7 6.7 11.7 0.43 10.5 5.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans_2 PF11951.8 OAG03456.1 - 1.2e-52 179.1 0.1 1.5e-52 178.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03456.1 - 2.9e-06 27.3 12.2 4.8e-06 26.6 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRISPR_Cse1 PF09481.10 OAG03456.1 - 0.0067 15.6 0.0 0.037 13.1 0.0 2.0 2 0 0 2 2 2 1 CRISPR-associated protein Cse1 (CRISPR_cse1) Cupin_1 PF00190.22 OAG03459.1 - 2.1e-18 66.4 0.2 3.3e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG03459.1 - 0.00028 20.5 0.1 0.0036 17.0 0.1 2.2 1 1 0 1 1 1 1 Cupin domain RAMA PF18755.1 OAG03459.1 - 0.041 14.3 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Restriction Enzyme Adenine Methylase Associated Coatomer_WDAD PF04053.14 OAG03461.1 - 9.3e-148 493.0 0.0 1.5e-147 492.3 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OAG03461.1 - 1.2e-95 320.7 0.0 1.6e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OAG03461.1 - 5.8e-35 118.7 17.0 2e-07 31.6 0.3 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG03461.1 - 1.1e-06 28.9 0.6 0.08 13.3 0.0 5.3 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG03461.1 - 0.027 13.1 6.1 2.3 6.8 0.1 3.6 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Transposase_1 PF01359.18 OAG03461.1 - 0.11 12.3 0.1 4 7.3 0.0 2.4 1 1 1 2 2 2 0 Transposase (partial DDE domain) Clathrin PF00637.20 OAG03461.1 - 1.2 9.0 3.4 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS tRNA-synt_1b PF00579.25 OAG03462.1 - 1.1e-61 208.7 0.0 1.7e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Cep57_MT_bd PF06657.13 OAG03462.1 - 0.022 15.2 2.6 0.067 13.6 2.6 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Sugarporin_N PF11471.8 OAG03462.1 - 0.23 11.4 1.9 0.71 9.9 1.9 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Spc24 PF08286.11 OAG03462.1 - 0.3 11.3 3.8 0.57 10.4 3.8 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.6 OAG03462.1 - 0.31 11.4 2.6 0.75 10.2 2.6 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 OAG03462.1 - 3.3 8.4 9.1 0.27 11.9 3.7 2.0 2 0 0 2 2 2 0 SlyX MFS_1 PF07690.16 OAG03463.1 - 5.9e-47 160.3 70.5 1e-41 143.0 45.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03463.1 - 2e-06 26.9 11.5 2e-06 26.9 11.5 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter LacY_symp PF01306.19 OAG03463.1 - 3.2e-05 22.9 7.3 4.2e-05 22.5 0.8 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter ANP PF00212.18 OAG03464.1 - 0.9 9.8 5.3 0.26 11.5 0.8 2.2 2 0 0 2 2 2 0 Atrial natriuretic peptide Indigoidine_A PF04227.12 OAG03465.1 - 4.5e-121 403.7 0.3 6.4e-121 403.2 0.3 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 OAG03465.1 - 1.6e-25 90.0 0.0 1.9e-13 50.4 0.0 2.8 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAG03465.1 - 0.022 14.1 0.0 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase Ribophorin_I PF04597.14 OAG03466.1 - 1.2e-157 525.6 0.4 1.4e-157 525.4 0.4 1.0 1 0 0 1 1 1 1 Ribophorin I Tetraspanin PF00335.20 OAG03467.1 - 0.061 13.0 2.0 0.094 12.4 2.0 1.3 1 0 0 1 1 1 0 Tetraspanin family VTC PF09359.10 OAG03468.1 - 3.5e-98 328.4 0.4 7.6e-98 327.3 0.4 1.6 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 OAG03468.1 - 2.6e-15 57.2 10.1 6.9e-07 29.5 0.1 4.1 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 OAG03468.1 - 5.9e-12 45.9 6.4 1.2e-11 44.9 6.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Elongin_A PF06881.11 OAG03469.1 - 5.2e-32 110.5 1.8 7.4e-32 110.0 1.8 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A THOC7 PF05615.13 OAG03470.1 - 1.4e-26 93.3 6.1 1.4e-26 93.3 6.1 2.6 1 1 1 2 2 2 1 Tho complex subunit 7 Peroxin-13_N PF04088.13 OAG03470.1 - 0.076 13.3 1.5 0.14 12.5 1.3 1.5 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Syntaxin_2 PF14523.6 OAG03470.1 - 0.56 10.6 6.8 1.4 9.3 6.4 2.0 1 1 0 1 1 1 0 Syntaxin-like protein DUF4094 PF13334.6 OAG03470.1 - 1.6 9.2 5.6 5.1 7.6 5.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Fib_alpha PF08702.10 OAG03470.1 - 3.3 7.9 10.6 5.5 7.2 10.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TBCA PF02970.16 OAG03471.1 - 5.8e-26 90.6 5.2 5.8e-26 90.6 5.2 1.5 1 1 1 2 2 2 1 Tubulin binding cofactor A FapA PF03961.13 OAG03471.1 - 0.019 13.6 3.6 0.022 13.4 3.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Zw10 PF06248.13 OAG03471.1 - 0.03 12.9 2.5 0.031 12.9 2.5 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF4446 PF14584.6 OAG03471.1 - 0.031 14.3 0.8 0.045 13.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4972 PF16342.5 OAG03471.1 - 0.054 13.2 2.2 0.071 12.8 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF1910 PF08928.10 OAG03471.1 - 0.16 12.0 2.0 0.25 11.3 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) Cytochrom_B562 PF07361.11 OAG03471.1 - 0.28 11.9 7.1 2.6 8.7 6.4 2.1 1 1 1 2 2 2 0 Cytochrome b562 Tho2 PF11262.8 OAG03471.1 - 0.36 10.0 2.3 0.4 9.8 2.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ABC_tran_CTD PF16326.5 OAG03471.1 - 2.5 8.4 11.4 3.5 7.9 3.6 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain MCM PF00493.23 OAG03472.1 - 2.3e-100 334.3 0.0 6.1e-100 332.9 0.0 1.7 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG03472.1 - 8.3e-39 132.3 0.6 1.5e-38 131.5 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG03472.1 - 2.9e-29 101.3 2.4 7e-29 100.1 2.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG03472.1 - 1.5e-14 54.4 0.0 6.3e-14 52.4 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OAG03472.1 - 1.1e-06 28.7 0.0 1e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAG03472.1 - 1.1e-05 24.9 0.0 0.00024 20.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAG03472.1 - 0.0002 21.2 0.1 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.13 OAG03472.1 - 0.037 14.1 0.3 0.089 12.8 0.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AAA_32 PF13654.6 OAG03472.1 - 0.06 12.1 0.4 0.12 11.1 0.4 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAG03472.1 - 0.12 12.1 0.1 3.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.6 OAG03472.1 - 0.37 11.1 3.0 0.75 10.2 0.0 2.8 2 2 1 3 3 3 0 AAA ATPase domain MR_MLE_C PF13378.6 OAG03473.1 - 3.5e-56 190.2 0.1 4.4e-56 189.9 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAG03473.1 - 1.9e-15 57.1 0.0 4.1e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Abhydrolase_3 PF07859.13 OAG03474.1 - 9.1e-17 61.6 0.0 1.9e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG03474.1 - 5.1e-07 29.4 0.0 0.00047 19.7 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 OAG03474.1 - 0.00031 19.5 0.0 0.054 12.2 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 OAG03474.1 - 0.00067 19.0 0.1 0.0099 15.2 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 COesterase PF00135.28 OAG03474.1 - 0.012 14.5 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.16 OAG03474.1 - 0.015 15.1 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 OAG03474.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Cupin_1 PF00190.22 OAG03477.1 - 6.9e-21 74.4 0.1 9.2e-21 74.0 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG03477.1 - 4.4e-06 26.3 0.0 9e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 Cupin domain MannoseP_isomer PF01050.18 OAG03477.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Arginase PF00491.21 OAG03478.1 - 2.4e-77 260.2 0.4 2.8e-77 260.0 0.4 1.0 1 0 0 1 1 1 1 Arginase family Pyr_redox_2 PF07992.14 OAG03479.1 - 1.1e-39 136.4 0.3 2.4e-35 122.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG03479.1 - 2e-11 44.3 0.0 3.9e-09 36.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG03479.1 - 0.014 14.6 0.1 4.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG03479.1 - 0.065 13.7 0.3 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Period_C PF12114.8 OAG03480.1 - 8.6 5.9 11.8 16 5.0 11.8 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region WSC PF01822.19 OAG03481.1 - 3e-11 43.4 2.9 6.3e-11 42.3 2.9 1.6 1 0 0 1 1 1 1 WSC domain Toxin_3 PF00537.18 OAG03481.1 - 3.1 8.1 6.5 2.5 8.4 2.6 2.2 1 1 1 2 2 2 0 Scorpion toxin-like domain Glyco_hydro_20 PF00728.22 OAG03482.1 - 1.8e-90 303.9 0.0 2.4e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAG03482.1 - 1.7e-27 96.8 0.0 4.1e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAG03482.1 - 0.00086 20.1 0.0 0.0058 17.4 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 OAG03483.1 - 6.6e-63 213.1 0.0 8.1e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TM_helix PF05552.12 OAG03483.1 - 0.034 14.1 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 Conserved TM helix Hydrolase_4 PF12146.8 OAG03484.1 - 7.7e-26 90.8 0.1 7.9e-25 87.5 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG03484.1 - 3.5e-23 82.6 0.1 1.7e-20 73.7 0.4 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG03484.1 - 1.2e-17 65.3 0.0 2e-17 64.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OAG03484.1 - 3.2e-06 26.0 0.0 4.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 OAG03484.1 - 5.5e-05 23.1 0.2 0.93 9.2 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 OAG03484.1 - 0.00011 22.1 0.1 0.0022 17.9 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.7 OAG03484.1 - 0.00018 21.3 0.0 0.0021 17.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OAG03484.1 - 0.00051 19.0 0.1 0.0012 17.9 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 OAG03484.1 - 0.0014 18.2 0.0 0.36 10.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 OAG03484.1 - 0.0023 18.1 0.0 0.0051 16.9 0.1 1.5 2 0 0 2 2 2 1 Thioesterase domain DUF676 PF05057.14 OAG03484.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_4 PF08386.10 OAG03484.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 OAG03484.1 - 0.012 15.2 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 OAG03484.1 - 0.015 15.0 3.7 0.11 12.3 3.7 2.0 1 1 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.13 OAG03484.1 - 0.021 13.4 2.1 1.7 7.1 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 OAG03484.1 - 0.035 13.8 0.0 0.041 13.5 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Acyl_transf_1 PF00698.21 OAG03484.1 - 0.04 13.4 0.3 0.06 12.8 0.3 1.2 1 0 0 1 1 1 0 Acyl transferase domain UPF0227 PF05728.12 OAG03484.1 - 0.047 13.6 0.2 0.077 12.9 0.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 OAG03484.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1100 PF06500.11 OAG03484.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Palm_thioest PF02089.15 OAG03484.1 - 0.17 11.7 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Cyt-b5 PF00173.28 OAG03486.1 - 6.1e-18 64.7 0.3 6.8e-18 64.6 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC_membrane PF00664.23 OAG03487.1 - 2.7e-38 132.2 12.3 3.4e-38 131.9 12.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG03487.1 - 2.9e-34 118.5 0.0 6.6e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG03487.1 - 6.1e-06 25.8 0.0 0.0049 16.3 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG03487.1 - 0.00022 21.7 0.1 0.00065 20.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 OAG03487.1 - 0.0007 19.6 0.0 0.021 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG03487.1 - 0.0014 18.9 0.1 0.032 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG03487.1 - 0.0016 18.8 0.0 0.0092 16.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 OAG03487.1 - 0.0025 17.7 0.1 0.028 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAG03487.1 - 0.0077 16.3 0.0 0.059 13.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OAG03487.1 - 0.018 14.8 0.1 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 OAG03487.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 OAG03487.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 OAG03487.1 - 0.025 14.3 0.0 0.064 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG03487.1 - 0.026 15.0 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG03487.1 - 0.034 13.9 0.3 6.4 6.5 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 OAG03487.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 OAG03487.1 - 0.036 13.6 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAG03487.1 - 0.036 13.3 0.0 0.1 11.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 OAG03487.1 - 0.06 12.3 0.1 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_7 PF12775.7 OAG03487.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 OAG03487.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG03487.1 - 0.099 13.2 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OAG03487.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 OAG03487.1 - 0.14 12.1 0.0 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AIM24 PF01987.17 OAG03488.1 - 1.5e-52 178.3 0.0 1.8e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Lebercilin PF15619.6 OAG03491.1 - 0.0095 15.6 26.1 0.0095 15.6 26.1 2.4 3 1 1 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.6 OAG03491.1 - 0.21 10.9 15.9 0.37 10.1 15.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 OAG03491.1 - 1.1 9.5 20.4 0.27 11.5 4.1 4.0 3 1 0 3 3 3 0 Haemolysin XhlA FUSC PF04632.12 OAG03491.1 - 1.2 7.5 6.2 2.5 6.6 6.2 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 OAG03491.1 - 1.6 8.9 34.6 0.77 9.9 16.4 4.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 OAG03491.1 - 2.1 7.3 16.4 4.1 6.4 16.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KELK PF15796.5 OAG03491.1 - 5.4 7.5 32.7 0.29 11.6 18.1 3.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Methyltransf_31 PF13847.6 OAG03492.1 - 3.3e-20 72.4 0.0 4.1e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG03492.1 - 9.1e-15 55.2 0.1 1.5e-14 54.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG03492.1 - 1.1e-12 48.5 0.0 1.7e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG03492.1 - 7.3e-12 45.8 0.0 1.7e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG03492.1 - 4.7e-11 42.5 0.0 8.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 OAG03492.1 - 2.3e-10 40.6 0.0 3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG03492.1 - 6.4e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAG03492.1 - 3e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OAG03492.1 - 0.00045 19.6 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 OAG03492.1 - 0.0053 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltr_RsmB-F PF01189.17 OAG03492.1 - 0.0074 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FmrO PF07091.11 OAG03492.1 - 0.037 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.13 OAG03492.1 - 0.045 13.1 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 OAG03492.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 OAG03492.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_5 PF01795.19 OAG03492.1 - 0.25 10.8 0.0 0.34 10.4 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family DSBA PF01323.20 OAG03493.1 - 2.7e-37 128.4 0.0 3.1e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 OAG03493.1 - 1.6e-05 25.1 0.1 5.4e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 OAG03493.1 - 0.00023 20.9 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 OAG03493.1 - 0.046 13.8 0.1 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Cellulase PF00150.18 OAG03494.1 - 6.4e-10 38.9 7.1 7.2e-09 35.5 7.0 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.13 OAG03495.1 - 9.9e-38 130.1 0.1 1.5e-37 129.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG03495.1 - 0.00034 19.6 0.0 0.00088 18.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 OAG03495.1 - 0.02 15.0 0.4 0.032 14.3 0.4 1.2 1 0 0 1 1 1 0 Thioesterase domain WD40 PF00400.32 OAG03496.1 - 2.3e-14 53.6 17.0 0.0054 17.5 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.6 OAG03497.1 - 2.8e-37 128.8 0.1 3.8e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 OAG03497.1 - 3.8e-07 30.1 4.9 7.9e-07 29.1 4.9 1.5 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 OAG03497.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 CUE domain Kelch_5 PF13854.6 OAG03498.1 - 1.3e-17 63.4 5.7 4.6e-10 39.3 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OAG03498.1 - 7.6e-11 41.9 11.2 0.21 11.9 0.2 6.0 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 OAG03498.1 - 2.7e-09 36.9 9.1 0.18 11.9 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG03498.1 - 7.6e-09 35.7 8.7 0.021 15.1 0.0 5.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG03498.1 - 0.00051 19.9 1.8 0.22 11.6 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 OAG03498.1 - 0.00052 19.6 8.2 0.25 11.0 0.0 4.5 5 0 0 5 5 5 2 Kelch motif PBP1_TM PF14812.6 OAG03498.1 - 0.055 13.9 0.3 0.11 12.9 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal p450 PF00067.22 OAG03500.1 - 6.1e-46 157.1 0.0 7.3e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 OAG03501.1 - 6.7e-97 325.2 22.8 8.1e-97 324.9 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG03501.1 - 1.7e-20 73.3 31.4 1.8e-17 63.4 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 OAG03502.1 - 2.7e-81 273.3 0.0 3.5e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG03502.1 - 3.2e-13 50.5 0.1 7.6e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rho_RNA_bind PF07497.12 OAG03502.1 - 0.012 15.4 0.0 0.068 13.1 0.0 2.2 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain 3HCDH_N PF02737.18 OAG03503.1 - 6e-36 124.0 0.0 9e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG03503.1 - 8.1e-12 45.6 0.0 1.7e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG03503.1 - 0.096 12.9 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Redoxin PF08534.10 OAG03504.1 - 5.9e-28 97.4 0.0 6.8e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG03504.1 - 1.9e-07 31.0 0.0 2.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.17 OAG03505.1 - 6.8e-31 106.7 2.9 9.9e-31 106.2 1.8 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 OAG03505.1 - 1.9e-22 79.5 0.0 5.9e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain W2 PF02020.18 OAG03505.1 - 6.7e-12 45.4 7.5 2.8e-11 43.4 6.7 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OAG03505.1 - 2.5e-09 36.5 17.8 0.00027 20.5 8.0 4.1 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OAG03505.1 - 2.1e-07 30.8 0.0 3.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 OAG03505.1 - 0.00019 21.8 0.0 0.00041 20.7 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 OAG03505.1 - 0.0039 15.4 1.4 0.015 13.5 0.5 2.1 1 1 2 3 3 3 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 OAG03505.1 - 0.082 12.7 14.8 3.7 7.4 0.2 3.6 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OAG03505.1 - 0.29 10.0 3.7 2.2 7.1 0.0 2.5 2 1 1 3 3 3 0 L-fucokinase IBR PF01485.21 OAG03506.1 - 7.7e-23 80.5 46.7 2.5e-12 46.8 6.6 4.5 3 1 1 4 4 4 4 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAG03506.1 - 3.3e-05 23.7 40.4 0.00024 20.9 5.9 4.4 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG03506.1 - 0.00024 21.3 4.0 0.00024 21.3 4.0 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG03506.1 - 0.0092 15.8 5.8 0.0092 15.8 5.8 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG03506.1 - 0.0097 15.9 4.1 0.0097 15.9 4.1 3.9 3 1 0 3 3 3 1 RING-type zinc-finger Trp_syntA PF00290.20 OAG03506.1 - 0.032 13.1 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Helicase_IV_N PF12462.8 OAG03506.1 - 0.1 12.6 3.2 0.24 11.3 3.2 1.6 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DNA_ligase_ZBD PF03119.16 OAG03506.1 - 3.9 7.6 10.9 1.8 8.6 0.3 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain NifU_N PF01592.16 OAG03507.1 - 7.5e-44 149.0 0.1 8.9e-44 148.7 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 OAG03507.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain UCH PF00443.29 OAG03508.1 - 6.1e-37 127.5 0.0 7.8e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG03508.1 - 6.3e-22 78.6 0.0 2.2e-18 66.9 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 OAG03508.1 - 4.6e-21 74.3 0.0 2e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 OAG03508.1 - 4.8e-20 71.7 1.0 4.8e-20 71.7 1.0 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA_4 PF14555.6 OAG03508.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Mso1_C PF14477.6 OAG03509.1 - 0.13 12.7 0.5 0.26 11.7 0.5 1.5 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 Ammonium_transp PF00909.21 OAG03511.1 - 5e-116 387.7 33.7 5.7e-116 387.5 33.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Clat_adaptor_s PF01217.20 OAG03512.1 - 8.8e-56 187.8 1.1 1e-55 187.6 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sec23_trunk PF04811.15 OAG03513.1 - 7.2e-56 189.5 0.0 1.6e-55 188.3 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAG03513.1 - 2.5e-26 91.5 0.0 4.6e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAG03513.1 - 6.2e-18 65.3 0.0 1.1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAG03513.1 - 4.2e-16 58.7 5.8 1.1e-15 57.3 5.8 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAG03513.1 - 2.5e-06 27.3 0.0 5.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.6 OAG03513.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Ribosomal_L27A PF00828.19 OAG03514.1 - 6.5e-23 81.8 0.0 9.5e-23 81.3 0.0 1.2 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glyco_hydro_cc PF11790.8 OAG03515.1 - 1.6e-66 224.3 0.1 1.9e-66 224.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TRP PF06011.12 OAG03516.1 - 6.6e-144 479.8 15.1 8.4e-144 479.4 15.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG03516.1 - 3.2e-38 131.2 0.8 5.7e-38 130.4 0.8 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 OAG03516.1 - 2.8e-05 24.6 0.9 4.6e-05 23.9 0.9 1.4 1 0 0 1 1 1 1 ML domain TMEM154 PF15102.6 OAG03516.1 - 0.55 10.1 2.6 1.9 8.4 0.8 2.4 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 OAG03516.1 - 2 9.3 0.0 2 9.3 0.0 3.3 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 OAG03516.1 - 2.9 8.0 6.3 0.68 10.0 0.1 3.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Glyco_hydro_15 PF00723.21 OAG03518.1 - 3.3e-40 138.2 0.0 3e-35 121.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Glyco_hydro81C PF17652.1 OAG03519.1 - 1.3e-157 524.5 1.0 1.7e-157 524.2 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OAG03519.1 - 4.7e-107 357.9 0.1 8e-107 357.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Fungal_trans PF04082.18 OAG03521.1 - 1.4e-09 37.4 3.0 2.7e-09 36.4 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03521.1 - 1.6e-06 28.1 9.1 3.5e-06 27.0 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG03522.1 - 1.4e-31 109.7 19.0 1.7e-31 109.4 19.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03522.1 - 2.3e-09 36.7 8.5 2.9e-09 36.3 8.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAG03522.1 - 3.1e-09 35.8 2.5 4.2e-09 35.4 2.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peroxidase_2 PF01328.17 OAG03523.1 - 1.3e-50 172.5 0.0 1.7e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 RRM_1 PF00076.22 OAG03524.1 - 2.1e-53 178.0 0.0 6.3e-18 64.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAG03524.1 - 0.00018 21.5 0.0 3.9 7.6 0.0 3.6 3 1 0 3 3 3 2 RNA binding motif RRM_5 PF13893.6 OAG03524.1 - 0.0012 18.4 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG03524.1 - 0.0032 17.3 0.0 5.2 7.0 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OAG03524.1 - 0.0062 16.6 0.2 7.8 6.6 0.0 4.0 4 1 0 4 4 4 1 Limkain b1 PknH_C PF14032.6 OAG03524.1 - 0.043 13.7 0.2 12 5.7 0.1 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain YoaP PF14268.6 OAG03524.1 - 0.069 12.7 1.2 3 7.4 0.0 2.7 3 0 0 3 3 3 0 YoaP-like ATP-grasp_2 PF08442.10 OAG03524.1 - 0.08 12.5 0.0 2.8 7.4 0.0 2.7 3 0 0 3 3 3 0 ATP-grasp domain RRM_9 PF18444.1 OAG03524.1 - 0.17 11.7 0.0 7.9 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif THRAP3_BCLAF1 PF15440.6 OAG03524.1 - 0.42 9.6 25.3 0.59 9.1 25.3 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Mito_carr PF00153.27 OAG03525.1 - 1.8e-50 168.8 0.2 1.3e-19 69.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PAP2_3 PF14378.6 OAG03527.1 - 2.9e-22 79.3 17.4 2.9e-22 79.3 17.4 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 OAG03527.1 - 4e-07 29.9 6.7 1.4e-06 28.1 6.7 2.0 1 0 0 1 1 1 1 PAP2 superfamily DUF1100 PF06500.11 OAG03529.1 - 2.2e-10 39.9 0.0 3.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 OAG03529.1 - 0.00011 21.9 0.2 0.039 13.6 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG03529.1 - 0.00015 21.1 0.1 0.00032 20.0 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG03529.1 - 0.00072 19.3 0.0 0.011 15.4 0.0 2.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAG03529.1 - 0.0026 17.6 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAG03529.1 - 0.0033 18.1 0.3 0.0062 17.2 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 OAG03529.1 - 0.0049 16.8 0.0 0.0097 15.9 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 OAG03529.1 - 0.02 14.5 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAG03529.1 - 0.026 14.0 0.1 0.053 13.0 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.25 OAG03530.1 - 4.4e-36 124.6 0.0 8.1e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03530.1 - 5.1e-25 88.2 0.0 9.1e-25 87.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase O-antigen_lig PF13425.6 OAG03532.1 - 0.023 13.5 3.0 0.029 13.2 3.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FluMu_N PF17891.1 OAG03532.1 - 0.12 12.2 1.2 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain DUF812 PF05667.11 OAG03532.1 - 0.74 8.6 12.5 1.3 7.9 12.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 OAG03532.1 - 0.81 9.0 10.8 1.1 8.6 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 OAG03532.1 - 2.3 8.9 6.2 1.8 9.3 3.9 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Hydantoinase_B PF02538.14 OAG03533.1 - 1.3e-215 716.7 0.1 2e-215 716.1 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAG03533.1 - 2.8e-102 341.9 0.2 5.7e-102 340.9 0.2 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG03533.1 - 9.2e-62 207.9 2.3 1e-60 204.5 0.1 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Glyco_hydro_43 PF04616.14 OAG03534.1 - 6.2e-32 111.1 0.5 7.4e-32 110.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SLD5_C PF16922.5 OAG03535.1 - 2.2e-18 66.2 2.0 3.2e-18 65.7 0.9 1.8 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OAG03535.1 - 0.00091 19.7 0.0 0.0015 19.0 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein Rhodanese PF00581.20 OAG03536.1 - 5.1e-14 52.7 0.1 9.5e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.13 OAG03539.1 - 3e-203 677.1 19.9 3.8e-203 676.7 19.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 OAG03539.1 - 0.0038 16.7 17.1 0.0076 15.7 17.1 1.4 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 OAG03539.1 - 0.0048 15.2 16.5 0.013 13.8 16.5 1.7 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 OAG03539.1 - 0.16 11.2 22.4 0.42 9.9 22.4 1.7 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.7 OAG03540.1 - 0.00015 21.5 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG03540.1 - 0.069 13.1 0.5 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 F-box domain DUF5487 PF17589.2 OAG03541.1 - 0.022 15.0 0.1 0.058 13.7 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5487) APG6_N PF17675.1 OAG03542.1 - 3.8 8.1 8.9 0.97 10.0 4.1 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region CCDC53 PF10152.9 OAG03542.1 - 9 6.7 10.8 0.47 10.9 2.3 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DnaJ PF00226.31 OAG03543.1 - 1.3e-25 89.3 2.6 2.2e-25 88.6 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OAG03543.1 - 7.2e-24 84.6 0.0 1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OAG03543.1 - 1.9e-14 53.7 15.7 3.1e-14 53.1 15.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAG03543.1 - 7.5e-06 25.8 8.7 0.0015 18.5 1.1 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAG03543.1 - 0.0015 18.5 7.1 0.29 11.1 1.0 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 OAG03543.1 - 0.0016 18.8 10.1 0.03 14.7 1.2 2.9 1 1 2 3 3 3 2 Restriction alleviation protein Lar TackOD1 PF18551.1 OAG03543.1 - 2.2 7.9 6.1 1.5 8.4 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 OAG03543.1 - 7.2 6.7 11.7 37 4.5 11.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S17 PF00366.20 OAG03544.1 - 2.4e-17 62.8 0.5 4.3e-17 62.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 CopG_antitoxin PF12441.8 OAG03544.1 - 0.034 14.7 0.4 0.1 13.1 0.2 1.9 1 1 1 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system Pkinase PF00069.25 OAG03545.1 - 1.7e-42 145.6 0.0 7.8e-39 133.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03545.1 - 2.7e-11 43.2 0.0 1.9e-08 33.9 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG03545.1 - 0.0015 17.4 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Cnd1 PF12717.7 OAG03546.1 - 1.8e-44 151.7 11.0 9.1e-41 139.6 0.7 4.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG03546.1 - 1.1e-08 34.6 4.8 0.26 11.7 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 OAG03546.1 - 7.9e-07 29.4 1.6 0.00091 19.6 0.1 3.7 4 0 0 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 OAG03546.1 - 0.00014 20.5 14.1 0.019 13.5 0.1 4.7 3 2 2 5 5 5 2 Adaptin N terminal region RTP1_C1 PF10363.9 OAG03546.1 - 0.00043 20.4 1.1 0.55 10.4 0.0 3.4 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 OAG03546.1 - 0.0055 15.9 0.9 0.0055 15.9 0.9 3.4 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain Dehyd-heme_bind PF09098.10 OAG03546.1 - 0.028 14.0 0.2 0.93 9.1 0.1 2.5 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding YtzH PF14165.6 OAG03546.1 - 0.062 13.7 0.2 0.35 11.3 0.1 2.3 2 0 0 2 2 2 0 YtzH-like protein HEAT_EZ PF13513.6 OAG03546.1 - 0.4 11.2 9.8 37 4.9 0.3 5.1 6 0 0 6 6 6 0 HEAT-like repeat T5orf172 PF10544.9 OAG03548.1 - 6.6e-15 55.5 0.0 1.7e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAG03548.1 - 1.4e-07 32.0 0.0 5.5e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 RCR PF12273.8 OAG03549.1 - 2.8e-23 82.8 10.8 4e-23 82.3 10.8 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 OAG03549.1 - 1e-05 25.4 0.6 1.2e-05 25.2 0.6 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Shisa PF13908.6 OAG03549.1 - 0.0048 17.2 0.0 0.0062 16.8 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 OAG03549.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) 7tm_7 PF08395.12 OAG03549.1 - 0.14 11.3 1.0 0.17 11.0 1.0 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor TMEM52 PF14979.6 OAG03549.1 - 0.22 11.5 0.2 0.34 10.8 0.2 1.3 1 0 0 1 1 1 0 Transmembrane 52 Arf PF00025.21 OAG03550.1 - 1.3e-44 151.7 0.0 1.5e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OAG03550.1 - 1.5e-18 66.9 0.0 1.7e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG03550.1 - 1.4e-15 57.6 0.0 2.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG03550.1 - 1.9e-07 30.7 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAG03550.1 - 1.6e-06 28.2 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG03550.1 - 2.6e-06 27.0 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAG03550.1 - 0.0013 18.0 0.1 0.0058 15.8 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 OAG03550.1 - 0.007 15.9 0.3 0.017 14.7 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG03550.1 - 0.071 13.2 0.0 0.31 11.1 0.1 1.8 1 1 1 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 OAG03550.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RNA_pol_Rpb2_6 PF00562.28 OAG03551.1 - 4.5e-113 378.2 0.0 6e-113 377.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG03551.1 - 8.7e-37 126.6 0.0 1.3e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OAG03551.1 - 2.7e-28 97.9 0.0 7.6e-28 96.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 OAG03551.1 - 2.4e-24 85.1 0.0 5.2e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 OAG03551.1 - 4.5e-24 85.1 0.0 7.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAG03551.1 - 9e-15 54.9 0.0 2.1e-13 50.5 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Rpr2 PF04032.16 OAG03551.1 - 0.13 12.5 1.5 0.28 11.5 1.5 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TFIIIC_sub6 PF10419.9 OAG03552.1 - 1.4e-19 69.8 0.0 2.4e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain DUF3438 PF11920.8 OAG03553.1 - 0.11 11.7 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) DUF3431 PF11913.8 OAG03554.1 - 2e-83 279.4 0.3 2.6e-83 279.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DNA_methylase PF00145.17 OAG03556.1 - 1.4e-23 83.8 0.0 1.5e-22 80.4 0.0 2.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 OAG03556.1 - 2.3e-09 37.1 0.4 0.0013 18.5 0.0 3.1 2 1 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 OAG03556.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain Amidohydro_2 PF04909.14 OAG03557.1 - 4.9e-06 26.5 0.0 1.6e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.20 OAG03557.1 - 0.00019 20.8 0.0 0.00039 19.8 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.6 OAG03557.1 - 0.08 13.4 0.2 0.44 11.0 0.0 2.2 2 1 0 3 3 3 0 CoA binding domain FRQ PF09421.10 OAG03559.1 - 3.1e-140 469.1 57.1 3.1e-140 469.1 57.1 2.0 2 1 0 2 2 2 1 Frequency clock protein COQ9 PF08511.11 OAG03561.1 - 1.3e-33 114.6 0.1 2e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 COQ9 WD40 PF00400.32 OAG03562.1 - 1.9e-11 44.3 0.7 0.3 12.0 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 OAG03562.1 - 0.045 12.4 0.1 4.5 5.8 0.1 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Big_9 PF17963.1 OAG03563.1 - 0.2 12.4 1.3 2.9 8.7 0.3 2.3 1 1 1 2 2 2 0 Bacterial Ig domain SHMT PF00464.19 OAG03564.1 - 1.4e-196 652.8 0.0 1.7e-196 652.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DNA_methylase PF00145.17 OAG03567.1 - 1.9e-28 99.8 0.0 4.7e-21 75.5 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase DUF3791 PF12668.7 OAG03567.1 - 0.043 13.9 0.4 0.13 12.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) TPR_1 PF00515.28 OAG03568.1 - 3e-10 39.5 5.6 0.0014 18.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG03568.1 - 2.4e-07 30.3 4.5 0.47 10.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF3808 PF10300.9 OAG03568.1 - 0.001 17.9 0.3 0.0017 17.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 OAG03568.1 - 0.0064 16.7 3.2 0.0064 16.7 3.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAG03568.1 - 0.098 13.5 0.0 9.3 7.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG03568.1 - 0.12 12.7 2.9 24 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG03568.1 - 0.41 11.2 2.8 1.1 9.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Mcp5_PH PF12814.7 OAG03569.1 - 8.4e-41 138.9 0.0 1.6e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ATG16 PF08614.11 OAG03569.1 - 8.8e-05 22.8 2.4 0.00038 20.7 2.4 2.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 OAG03569.1 - 0.0055 17.2 10.3 0.012 16.0 10.3 1.5 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 OAG03569.1 - 0.017 15.1 15.5 1.6 8.8 0.3 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 OAG03569.1 - 0.17 12.1 16.0 0.11 12.7 11.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4047 PF13256.6 OAG03569.1 - 0.21 11.8 0.5 0.42 10.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Exonuc_VII_L PF02601.15 OAG03569.1 - 0.31 10.6 5.2 0.51 9.8 5.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 OAG03569.1 - 0.33 11.0 1.9 0.66 10.0 1.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.18 OAG03569.1 - 0.5 10.6 0.0 0.5 10.6 0.0 2.7 3 0 0 3 3 2 0 Homeobox associated leucine zipper Prefoldin PF02996.17 OAG03569.1 - 0.53 10.2 2.8 1 9.3 2.8 1.4 1 0 0 1 1 1 0 Prefoldin subunit Golgin_A5 PF09787.9 OAG03569.1 - 0.76 9.2 13.8 1.4 8.3 13.8 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 PRKG1_interact PF15898.5 OAG03569.1 - 1 10.3 14.2 0.096 13.6 3.8 2.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain IFT57 PF10498.9 OAG03569.1 - 1 8.3 9.1 0.41 9.6 5.3 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 UPF0242 PF06785.11 OAG03569.1 - 1.1 9.4 6.1 2.5 8.2 6.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 OAG03569.1 - 1.7 7.2 6.2 2.5 6.6 6.2 1.1 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 OAG03569.1 - 1.8 8.7 5.9 6.5 6.9 0.1 2.7 2 0 0 2 2 2 0 bZIP transcription factor Atg14 PF10186.9 OAG03569.1 - 2.3 7.2 9.3 4.6 6.2 9.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OAG03569.1 - 5.1 5.9 13.3 9.3 5.0 13.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 OAG03569.1 - 6.8 5.1 11.2 0.039 12.5 2.6 1.6 2 0 0 2 2 2 0 Macoilin family MFS_1 PF07690.16 OAG03571.1 - 2.9e-35 121.9 26.4 4e-35 121.4 26.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cellulase PF00150.18 OAG03572.1 - 4.1e-16 59.2 6.8 5.9e-16 58.7 6.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RasGEF PF00617.19 OAG03573.1 - 1.4e-45 155.7 0.2 2.4e-45 154.9 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG03573.1 - 2.9e-12 46.7 0.5 7.3e-12 45.5 0.5 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Glyco_transf_22 PF03901.17 OAG03574.1 - 1.8e-83 281.1 26.9 2.3e-83 280.8 26.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3445 PF11927.8 OAG03574.1 - 3.4e-79 265.6 0.0 4.9e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Gar1 PF04410.14 OAG03575.1 - 1.7e-41 141.5 1.5 1.7e-41 141.5 1.5 2.3 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Med19 PF10278.9 OAG03575.1 - 0.48 10.3 12.5 3 7.7 2.8 2.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PP2C PF00481.21 OAG03576.1 - 1.1e-51 175.9 0.0 2e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OAG03576.1 - 6.2e-39 131.6 51.6 1.3e-10 40.9 6.3 10.5 7 3 4 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 OAG03576.1 - 4.8e-38 128.5 46.6 4.9e-05 23.6 0.4 12.9 9 2 2 12 12 12 10 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 OAG03576.1 - 5.8e-30 104.3 0.0 4.9e-29 101.3 0.0 2.1 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 OAG03576.1 - 4.7e-08 32.6 0.3 1.3e-07 31.2 0.3 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 OAG03576.1 - 9.8e-07 28.5 48.5 17 6.4 0.0 16.1 13 4 1 14 14 14 3 Leucine Rich Repeat LRR_9 PF14580.6 OAG03576.1 - 3.6e-05 23.3 15.0 0.048 13.2 0.8 4.8 2 1 3 5 5 5 3 Leucine-rich repeat RA PF00788.23 OAG03576.1 - 5.1e-05 23.8 0.1 0.00014 22.5 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.6 OAG03576.1 - 0.031 14.2 0.1 1.1 9.3 0.1 2.6 1 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) CorA PF01544.18 OAG03579.1 - 2.3e-12 46.9 0.2 4.2e-12 46.0 0.2 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Arena_ncap_C PF17290.2 OAG03579.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain ADH_zinc_N_2 PF13602.6 OAG03580.1 - 3.6e-13 50.7 0.0 1e-12 49.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG03580.1 - 3.7e-05 23.7 2.0 8.1e-05 22.6 0.1 2.4 2 1 0 3 3 3 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 OAG03580.1 - 0.0022 17.8 0.5 0.0034 17.2 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2855) Oxidored_nitro PF00148.19 OAG03580.1 - 0.027 13.2 0.1 0.047 12.4 0.1 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ADH_N PF08240.12 OAG03580.1 - 0.042 13.7 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 OAG03580.1 - 0.048 12.8 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF374 PF04028.13 OAG03580.1 - 0.05 13.2 0.2 0.094 12.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Pro_CA PF00484.19 OAG03581.1 - 0.00016 22.0 0.0 0.00041 20.7 0.0 1.7 1 1 0 1 1 1 1 Carbonic anhydrase Allantoicase PF03561.15 OAG03582.1 - 5.5e-92 305.3 0.1 6.7e-48 162.3 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 OAG03582.1 - 0.01 16.0 0.0 0.052 13.7 0.0 2.1 3 0 0 3 3 3 0 F5/8 type C domain DIL PF01843.19 OAG03583.1 - 7.4e-31 106.5 1.5 1.4e-30 105.6 1.5 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 OAG03583.1 - 5.5e-14 52.5 0.0 1.1e-12 48.3 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG03583.1 - 1.8e-11 44.3 0.0 4.3e-05 24.0 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG03583.1 - 1.8e-08 34.4 0.0 0.0036 17.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG03583.1 - 3.3e-06 27.3 0.0 8.6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG03583.1 - 5e-06 26.5 0.1 0.031 14.8 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Sir1 PF11603.8 OAG03583.1 - 0.15 12.5 0.0 0.52 10.8 0.1 1.8 2 0 0 2 2 2 0 Regulatory protein Sir1 HATPase_c PF02518.26 OAG03584.1 - 1.3e-30 106.2 0.0 2.9e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG03584.1 - 2.4e-20 72.3 0.0 1.1e-19 70.2 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 OAG03584.1 - 1.2e-17 64.1 0.0 3e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.6 OAG03584.1 - 8.4e-12 45.8 3.1 9.7e-12 45.6 0.2 2.7 3 0 0 3 3 3 1 AAA ATPase domain Pkinase PF00069.25 OAG03584.1 - 5.6e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GAF_2 PF13185.6 OAG03584.1 - 3.9e-09 36.9 0.0 9.8e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OAG03584.1 - 5.1e-06 27.2 0.0 1.5e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain NACHT PF05729.12 OAG03584.1 - 9.3e-06 25.6 0.0 0.014 15.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain GAF_3 PF13492.6 OAG03584.1 - 2.7e-05 24.5 0.2 9e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 GAF domain AAA_22 PF13401.6 OAG03584.1 - 0.02 15.2 0.1 0.17 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain TPR_12 PF13424.6 OAG03584.1 - 0.022 15.0 6.6 1.7 9.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Kinase-like PF14531.6 OAG03584.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Kinase-like LCM PF04072.14 OAG03585.1 - 5e-19 69.0 0.0 1.2e-18 67.7 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase RNA_pol_Rpb5_C PF01191.19 OAG03586.1 - 1.8e-33 114.2 0.1 1.2e-32 111.6 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OAG03586.1 - 9.1e-23 80.7 0.0 1.6e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain ATP_sub_h PF10775.9 OAG03586.1 - 0.36 10.8 1.8 0.31 11.1 0.3 1.6 2 0 0 2 2 2 0 ATP synthase complex subunit h CwfJ_C_1 PF04677.15 OAG03587.1 - 8.1e-22 77.4 0.0 4.3e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OAG03587.1 - 8.1e-16 58.7 2.4 1.8e-15 57.6 2.1 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.28 OAG03587.1 - 0.0033 17.9 0.1 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1524 PF07510.11 OAG03588.1 - 8e-11 42.0 0.0 9.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 OAG03588.1 - 0.21 11.5 0.3 0.57 10.1 0.3 1.8 1 1 0 1 1 1 0 HNH endonuclease F-box PF00646.33 OAG03589.1 - 2.2e-05 24.2 0.1 4.4e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG03589.1 - 0.00032 20.5 0.1 0.00061 19.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like TRI12 PF06609.13 OAG03592.1 - 3.7e-61 207.3 20.9 4.5e-61 207.0 20.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG03592.1 - 1e-17 64.1 43.2 5.8e-17 61.7 41.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03592.1 - 1e-15 57.6 4.2 1e-15 57.6 4.2 3.0 4 0 0 4 4 4 2 Sugar (and other) transporter AP_endonuc_2 PF01261.24 OAG03593.1 - 1.8e-28 99.4 0.1 2.8e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel EMP70 PF02990.16 OAG03594.1 - 3.3e-200 666.2 2.8 4.1e-200 665.9 2.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sua5_yciO_yrdC PF01300.18 OAG03595.1 - 2.9e-53 180.0 0.0 4.9e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OAG03595.1 - 4e-32 111.6 0.0 1e-31 110.2 0.0 1.7 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding PE PF00934.20 OAG03595.1 - 0.68 10.3 3.8 7.8 6.9 0.1 2.7 2 0 0 2 2 2 0 PE family Med3 PF11593.8 OAG03596.1 - 8.7 5.4 12.3 9.8 5.2 12.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zn_clus PF00172.18 OAG03597.1 - 1.2e-08 35.0 8.5 1.2e-08 35.0 8.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 OAG03598.1 - 2.4e-12 46.8 0.2 3.5e-12 46.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG03598.1 - 2.1e-05 24.3 0.6 0.00087 19.0 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG03598.1 - 0.00018 20.8 0.8 0.19 10.9 0.1 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG03598.1 - 0.00077 19.6 0.1 0.0021 18.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 OAG03598.1 - 0.014 15.9 0.2 0.075 13.6 0.0 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 OAG03598.1 - 0.041 12.7 0.3 1.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.6 OAG03598.1 - 0.066 13.2 0.3 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG03598.1 - 0.069 13.7 0.0 0.25 11.9 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAG03598.1 - 0.071 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) ApbA PF02558.16 OAG03598.1 - 0.076 12.6 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SIR2 PF02146.17 OAG03599.1 - 6.1e-53 179.4 0.0 9.4e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DASH_Spc19 PF08287.11 OAG03599.1 - 0.073 13.0 0.2 0.073 13.0 0.2 2.1 2 0 0 2 2 2 0 Spc19 Host_attach PF10116.9 OAG03599.1 - 1.1 9.8 5.0 0.29 11.7 1.2 1.9 2 0 0 2 2 2 0 Protein required for attachment to host cells SKG6 PF08693.10 OAG03600.1 - 0.01 15.2 0.7 0.022 14.2 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG03600.1 - 0.029 14.5 0.5 0.079 13.1 0.2 1.8 2 0 0 2 2 2 0 Podoplanin Stevor PF17410.2 OAG03600.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame FAD_binding_4 PF01565.23 OAG03605.1 - 8.9e-24 83.8 2.7 1.9e-23 82.7 2.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG03605.1 - 0.0012 18.8 0.3 0.0027 17.8 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.11 OAG03606.1 - 3.6e-30 105.2 0.0 1.4e-29 103.4 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 OAG03607.1 - 7.4e-38 130.0 0.3 1.2e-37 129.2 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG03607.1 - 6.6e-28 97.9 0.2 1.1e-27 97.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG03607.1 - 4.2e-07 30.0 4.0 2.3e-05 24.4 4.0 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG03607.1 - 0.00079 19.0 0.1 0.0019 17.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.16 OAG03608.1 - 1.1 9.9 3.5 1.4 9.6 0.1 3.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain V_ATPase_I PF01496.19 OAG03608.1 - 2.7 5.8 10.1 12 3.6 10.1 2.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RskA PF10099.9 OAG03609.1 - 8.5e-05 22.9 34.9 0.24 11.7 3.0 9.0 9 1 0 9 9 9 4 Anti-sigma-K factor rskA DUF4179 PF13786.6 OAG03609.1 - 0.56 10.7 3.4 6.9 7.2 1.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CSTF2_hinge PF14327.6 OAG03610.1 - 1.8e-31 108.4 1.6 2.5e-31 107.9 1.6 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 OAG03610.1 - 5.6e-19 67.7 0.0 7.8e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cu_amine_oxid PF01179.20 OAG03611.1 - 4.2e-159 529.9 0.0 6.2e-159 529.3 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAG03611.1 - 3.8e-10 39.9 0.2 7.5e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAG03611.1 - 8.7e-05 22.9 0.0 0.00032 21.0 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Chitin_bind_1 PF00187.19 OAG03612.1 - 1.1e-07 32.2 19.1 2e-07 31.4 19.1 1.4 1 0 0 1 1 1 1 Chitin recognition protein CBM_4_9 PF02018.17 OAG03612.1 - 0.00011 22.4 0.1 0.00031 21.0 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_61 PF03443.14 OAG03613.1 - 2.5e-49 168.0 0.5 2.9e-49 167.8 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GH131_N PF18271.1 OAG03614.1 - 9.4e-63 212.3 5.0 1.1e-62 212.1 5.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 OAG03614.1 - 0.0062 16.4 5.5 0.024 14.5 5.5 1.9 1 1 0 1 1 1 1 Polysaccharide lyase DUF2677 PF10838.8 OAG03615.1 - 0.33 10.9 3.3 0.81 9.6 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2677) ATG16 PF08614.11 OAG03616.1 - 0.0057 16.9 1.4 0.0057 16.9 1.4 9.3 5 4 1 8 8 8 1 Autophagy protein 16 (ATG16) UBA_2 PF08587.11 OAG03616.1 - 0.013 15.6 7.2 9.7 6.4 0.0 6.7 6 0 0 6 6 6 0 Ubiquitin associated domain (UBA) Baculo_PEP_C PF04513.12 OAG03616.1 - 0.12 12.5 30.7 2.4 8.2 0.1 8.9 6 2 2 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus Noelin-1 PF12308.8 OAG03616.1 - 1 9.4 7.5 2.6 8.1 0.7 4.9 3 0 0 3 3 3 0 Neurogenesis glycoprotein Ish1 PF10281.9 OAG03616.1 - 1.9 8.9 5.4 6.1 7.2 0.0 4.3 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein RPN6_N PF18055.1 OAG03617.1 - 2e-46 157.1 1.0 4.6e-46 156.0 0.2 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OAG03617.1 - 1.7e-21 76.7 0.3 6.4e-21 74.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 OAG03617.1 - 2.8e-11 42.9 0.4 6.8e-11 41.7 0.4 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 OAG03617.1 - 7.5e-06 25.5 3.0 0.0017 17.8 0.8 2.9 1 1 2 3 3 3 2 MalT-like TPR region TPR_7 PF13176.6 OAG03617.1 - 0.00023 20.9 3.4 1.9 8.7 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DDRGK PF09756.9 OAG03617.1 - 0.0049 16.5 0.1 0.0096 15.5 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_10 PF13374.6 OAG03617.1 - 0.028 14.3 0.2 6 6.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_membrane_2 PF06472.15 OAG03617.1 - 0.038 13.4 0.1 0.063 12.7 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 TPR_6 PF13174.6 OAG03617.1 - 0.046 14.4 1.9 2.8 8.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG03617.1 - 0.11 12.2 0.6 21 4.9 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 OAG03617.1 - 0.18 12.1 12.5 6 7.2 0.6 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat SbsC_C PF18058.1 OAG03617.1 - 0.41 10.9 3.0 1.5 9.1 0.0 2.9 3 0 0 3 3 3 0 SbsC C-terminal domain TPR_14 PF13428.6 OAG03617.1 - 0.53 11.2 7.7 2.1 9.4 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG03617.1 - 1.1 9.2 4.5 9.7 6.2 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Epimerase PF01370.21 OAG03618.1 - 0.00023 20.7 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Osmo_CC PF08946.10 OAG03619.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Vps62 PF06101.11 OAG03620.1 - 1.3e-09 36.9 0.4 2.5e-09 36.0 0.4 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 RNA_pol_Rpb1_5 PF04998.17 OAG03621.1 - 1.8e-88 296.5 0.0 3.6e-88 295.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAG03621.1 - 1.5e-67 227.0 0.3 2.9e-67 226.0 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAG03621.1 - 3.3e-33 114.9 0.0 8.2e-33 113.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 OAG03621.1 - 4.6e-24 85.3 4.2 1.1e-21 77.6 2.6 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 OAG03621.1 - 1.1e-19 70.4 0.6 4.9e-19 68.3 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.10 OAG03622.1 - 1.6e-66 224.2 1.7 3.6e-66 223.1 1.7 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OAG03622.1 - 5.6e-44 149.8 0.9 5.6e-44 149.8 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) BLUF PF04940.12 OAG03622.1 - 0.0051 16.9 0.1 1.6 8.9 0.0 2.7 2 0 0 2 2 2 2 Sensors of blue-light using FAD NICE-1 PF15845.5 OAG03622.1 - 0.79 10.5 5.1 1.9 9.3 5.1 1.6 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family Abhydrolase_6 PF12697.7 OAG03623.1 - 2.1e-16 61.2 11.0 3e-16 60.7 11.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_1 PF01979.20 OAG03625.1 - 5.2e-30 104.9 0.0 1.3e-29 103.6 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG03625.1 - 5.2e-17 62.5 0.1 1.4e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DUF1917 PF08939.10 OAG03626.1 - 1e-72 245.2 0.0 1.2e-72 245.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Homeobox_KN PF05920.11 OAG03626.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain DNA_primase_S PF01896.19 OAG03627.1 - 5.8e-61 205.6 0.0 9.9e-61 204.9 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit ubiquitin PF00240.23 OAG03628.1 - 4.7e-34 116.0 0.6 8e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 OAG03628.1 - 1.3e-26 92.5 2.1 1.3e-26 92.5 2.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OAG03628.1 - 2.7e-16 59.2 0.7 5e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG03628.1 - 3e-05 24.4 0.5 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG03628.1 - 0.0015 18.6 0.6 0.0035 17.4 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OAG03628.1 - 0.0053 17.1 1.1 0.0083 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG03628.1 - 0.0055 16.6 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OAG03628.1 - 0.012 16.1 0.8 0.018 15.6 0.8 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAG03628.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 OAG03628.1 - 0.059 13.6 0.3 0.1 12.8 0.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 OAG03629.1 - 3.3e-12 46.1 10.3 8e-06 26.0 2.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG03629.1 - 3e-10 40.1 6.9 0.00018 21.8 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG03629.1 - 1.7e-07 31.5 9.2 0.0068 17.1 1.4 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG03629.1 - 0.0021 17.8 2.7 0.45 10.3 0.5 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 OAG03629.1 - 0.029 14.4 7.0 5 7.2 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger MerR-DNA-bind PF09278.11 OAG03629.1 - 0.16 12.6 2.4 16 6.1 0.1 4.3 5 0 0 5 5 5 0 MerR, DNA binding zf-BED PF02892.15 OAG03629.1 - 0.35 10.9 4.3 4 7.6 0.1 2.5 1 1 1 2 2 2 0 BED zinc finger ARS2 PF04959.13 OAG03629.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.7 3 2 2 5 5 4 0 Arsenite-resistance protein 2 IBR PF01485.21 OAG03629.1 - 0.53 10.6 5.3 0.61 10.4 3.9 1.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 OAG03629.1 - 1.2 9.4 3.1 1.5 9.0 1.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-TRAF PF02176.18 OAG03629.1 - 2.3 9.0 5.3 3.5 8.4 2.1 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger Alginate_lyase2 PF08787.11 OAG03630.1 - 2.8e-45 155.0 0.0 3.3e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.6 OAG03630.1 - 0.033 14.0 0.3 0.071 12.9 0.3 1.6 1 1 0 1 1 1 0 Polysaccharide lyase DUF3435 PF11917.8 OAG03631.1 - 3.2e-06 26.3 0.0 4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.26 OAG03632.1 - 0.12 12.9 0.6 0.12 12.9 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNase_NucA_NucB PF14040.6 OAG03634.1 - 0.054 13.9 0.6 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB Propeptide_C25 PF08126.11 OAG03634.1 - 0.12 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Propeptide_C25 Acyl_transf_1 PF00698.21 OAG03635.1 - 1.3e-30 107.0 0.0 1.6e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 OAG03635.1 - 0.004 16.9 0.2 0.16 11.7 0.2 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Zn_clus PF00172.18 OAG03637.1 - 2.3e-07 30.8 10.8 4.4e-07 29.9 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG03637.1 - 8.7e-06 24.8 0.0 3.9e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2HE PF16278.5 OAG03639.1 - 0.09 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger WD40 PF00400.32 OAG03641.1 - 7.8e-37 124.6 26.4 0.00012 22.8 1.0 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG03641.1 - 4.3e-16 59.0 2.1 3.8e-05 23.9 0.2 6.9 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAG03641.1 - 0.00037 20.9 12.2 0.089 13.3 0.0 6.0 8 0 0 8 8 8 2 PQQ-like domain WD40_like PF17005.5 OAG03641.1 - 0.001 18.5 0.0 0.32 10.3 0.0 2.8 2 1 1 3 3 3 2 WD40-like domain PQQ PF01011.21 OAG03641.1 - 0.0021 17.9 3.9 4.3 7.4 0.2 4.0 3 0 0 3 3 3 2 PQQ enzyme repeat PD40 PF07676.12 OAG03641.1 - 0.066 13.2 1.2 22 5.2 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OAG03641.1 - 0.45 9.4 3.4 26 3.7 0.0 3.9 5 1 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Helicase_C_2 PF13307.6 OAG03642.1 - 2.6e-54 183.9 0.0 8.7e-54 182.2 0.0 2.0 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OAG03642.1 - 3.5e-50 170.1 0.1 6.1e-50 169.3 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 OAG03642.1 - 0.00014 21.9 0.1 0.081 12.9 0.1 2.8 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG03642.1 - 0.0087 15.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF883 PF05957.13 OAG03642.1 - 3.9 8.2 7.3 2.7 8.7 0.0 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Adeno_E3_CR2 PF02439.15 OAG03644.1 - 0.01 15.5 1.3 0.01 15.5 1.3 1.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 OAG03644.1 - 0.03 14.4 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Podoplanin LYRIC PF15686.5 OAG03644.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family EphA2_TM PF14575.6 OAG03644.1 - 0.083 13.8 0.0 0.13 13.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OAG03644.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.16 OAG03644.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.6 OAG03644.1 - 3.3 7.9 5.2 1.4 9.1 0.1 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator PTR2 PF00854.21 OAG03645.1 - 7.8e-89 298.3 5.8 1.9e-88 297.0 5.8 1.6 1 1 0 1 1 1 1 POT family Ctr PF04145.15 OAG03646.1 - 2.6e-44 151.4 0.5 3e-44 151.2 0.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 OAG03646.1 - 0.0088 15.8 4.3 0.14 11.9 4.8 2.0 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF485 PF04341.12 OAG03646.1 - 0.032 14.2 5.8 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 LapA_dom PF06305.11 OAG03646.1 - 0.054 13.3 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ycf70 PF17382.2 OAG03646.1 - 0.39 11.2 2.1 0.35 11.3 0.8 1.5 2 0 0 2 2 2 0 Uncharacterized Ycf70-like MSC PF09402.10 OAG03648.1 - 1.4e-103 346.9 0.0 2.1e-103 346.3 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 OAG03648.1 - 6.6e-15 54.5 0.1 2.1e-14 53.0 0.1 1.9 1 0 0 1 1 1 1 HeH/LEM domain PGA_cap PF09587.10 OAG03648.1 - 0.021 14.3 0.1 0.05 13.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap NMT1 PF09084.11 OAG03649.1 - 5e-11 42.9 0.0 9.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 OAG03649.1 - 1.7e-05 24.4 0.3 3.1e-05 23.5 0.1 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 OAG03649.1 - 0.0059 16.2 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 OAG03649.1 - 0.0075 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family DLH PF01738.18 OAG03650.1 - 4.4e-17 62.3 0.1 2.7e-14 53.2 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAG03650.1 - 0.012 15.3 0.0 4.9 6.7 0.0 2.9 2 1 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAG03650.1 - 0.052 13.4 0.1 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold LAT PF15234.6 OAG03650.1 - 0.21 11.3 0.9 0.33 10.7 0.0 1.8 3 0 0 3 3 3 0 Linker for activation of T-cells Rep_fac-A_C PF08646.10 OAG03651.1 - 3e-54 182.7 2.4 1.2e-52 177.5 1.2 2.5 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OAG03651.1 - 1.1e-35 121.5 0.5 2.3e-35 120.4 0.5 1.6 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 OAG03651.1 - 4.1e-22 78.1 0.2 1.1e-21 76.7 0.2 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OAG03651.1 - 2.6e-10 40.1 0.3 7.4e-06 25.9 0.0 3.8 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF4503 PF14951.6 OAG03651.1 - 0.00021 19.9 0.3 0.00041 18.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4503) CDC24_OB3 PF17244.2 OAG03651.1 - 0.00035 20.4 0.7 0.0015 18.3 0.1 2.3 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 OAG03651.1 - 0.071 13.2 0.0 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) Ribosomal_L44 PF00935.19 OAG03652.1 - 1.6e-36 124.6 11.4 2.6e-36 124.0 11.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 ApbA_C PF08546.11 OAG03653.1 - 1.9e-27 96.0 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG03653.1 - 8.4e-25 87.2 0.0 1.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 OAG03653.1 - 0.016 14.8 1.3 0.03 13.9 1.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAG03653.1 - 0.016 15.6 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 OAG03653.1 - 0.085 12.2 1.6 0.55 9.5 1.7 1.9 2 0 0 2 2 2 0 ThiF family IlvN PF07991.12 OAG03653.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_3 PF01494.19 OAG03653.1 - 0.2 10.9 0.5 0.33 10.1 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 OAG03653.1 - 1.2 8.1 2.9 2.2 7.3 2.9 1.4 1 0 0 1 1 1 0 FAD binding domain Peptidase_C28 PF05408.11 OAG03654.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Glyco_hydro_6 PF01341.17 OAG03655.1 - 4e-98 328.9 0.4 5.1e-98 328.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Cofilin_ADF PF00241.20 OAG03656.1 - 2.2e-23 82.4 0.4 2.5e-23 82.2 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HupH_C PF04809.13 OAG03658.1 - 0.16 11.6 0.1 0.49 10.1 0.1 1.8 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region HET PF06985.11 OAG03660.1 - 4.8e-28 98.3 0.3 9.5e-28 97.4 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MOZ_SAS PF01853.18 OAG03661.1 - 1.3e-59 200.9 0.0 1.7e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAG03661.1 - 6.4e-14 51.3 0.1 1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain HTH_15 PF12324.8 OAG03661.1 - 0.00012 21.9 0.2 0.00029 20.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase Acetyltransf_7 PF13508.7 OAG03661.1 - 0.018 15.5 0.0 0.057 13.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Mis14 PF08641.12 OAG03662.1 - 8.9e-05 22.8 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 Kinetochore protein Mis14 like RANK_CRD_2 PF18278.1 OAG03663.1 - 0.013 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 RasGAP PF00616.19 OAG03664.1 - 1.4e-59 201.3 2.1 1.8e-59 201.0 0.1 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAG03664.1 - 5e-30 104.4 4.1 5e-30 104.4 4.1 2.7 3 0 0 3 3 3 1 RasGAP C-terminus DUF1647 PF07801.11 OAG03664.1 - 0.18 11.5 2.0 0.28 10.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) TPR_8 PF13181.6 OAG03666.1 - 0.053 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG03666.1 - 0.073 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG03666.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG03666.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 TPR repeat SlyX PF04102.12 OAG03666.1 - 0.43 11.2 7.0 1.4 9.6 0.0 3.5 3 0 0 3 3 3 0 SlyX Helo_like_N PF17111.5 OAG03667.1 - 5.7e-12 45.4 0.1 9.7e-12 44.7 0.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Rad21_Rec8_N PF04825.13 OAG03668.1 - 2.8e-35 120.8 0.0 5.8e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAG03668.1 - 6.3e-05 22.2 0.0 0.00014 21.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 OAG03669.1 - 2.9e-45 154.0 1.0 4.4e-45 153.4 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG03669.1 - 2e-43 148.2 0.6 4.9e-43 147.0 0.6 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG03669.1 - 9.5e-23 81.6 0.9 3.5e-22 79.7 0.9 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG03669.1 - 6.6e-19 67.4 0.0 1.8e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAG03669.1 - 5.2e-13 48.9 0.0 1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG03669.1 - 0.00014 21.7 3.1 0.00045 20.1 1.3 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_A24 PF01478.18 OAG03669.1 - 0.008 16.6 0.0 1.9 8.9 0.0 3.2 3 1 0 3 3 3 1 Type IV leader peptidase family ATP-synt_F PF01990.17 OAG03669.1 - 0.088 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Sirohm_synth_M PF14824.6 OAG03670.1 - 0.002 17.6 0.1 0.0044 16.4 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TPR_19 PF14559.6 OAG03670.1 - 0.093 13.3 0.3 0.31 11.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG03670.1 - 0.095 12.9 1.3 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 OAG03671.1 - 5.2e-24 84.7 0.2 8.6e-24 84.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG03671.1 - 1.6e-21 77.7 0.0 2.4e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG03671.1 - 4.4e-07 29.8 0.0 2.9e-05 23.9 0.0 2.5 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 OAG03672.1 - 3.8e-32 111.6 24.4 3.8e-32 111.6 24.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 OAG03673.1 - 7.6e-05 23.0 14.1 0.02 15.4 3.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG03673.1 - 0.0003 21.1 3.8 0.0003 21.1 3.8 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG03673.1 - 0.008 16.9 13.5 0.081 13.8 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 OAG03673.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 OAG03673.1 - 8.9 6.2 7.7 6 6.7 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FmdA_AmdA PF03069.15 OAG03674.1 - 2.1e-179 596.2 0.0 2.3e-179 596.0 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 OAG03675.1 - 3.9e-15 56.5 1.6 1.9e-07 31.5 1.6 2.3 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 OAG03676.1 - 1.4e-38 132.0 0.0 3.1e-38 130.9 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Homeodomain PF00046.29 OAG03677.1 - 2.3e-11 43.3 0.2 6.1e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG03677.1 - 9.1e-08 31.9 0.0 2.5e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.6 OAG03677.1 - 8.3e-05 23.1 19.5 0.008 16.9 0.7 5.4 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG03677.1 - 0.00081 19.7 21.1 0.12 12.9 0.7 5.3 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 OAG03677.1 - 0.028 15.1 7.0 0.065 13.9 0.1 3.2 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats CCDC106 PF15794.5 OAG03677.1 - 5.1 6.7 6.9 12 5.5 6.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Sec23_trunk PF04811.15 OAG03678.1 - 3.1e-64 216.9 0.0 6.8e-64 215.8 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAG03678.1 - 4.8e-22 77.7 0.0 1.5e-21 76.2 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAG03678.1 - 4e-17 62.0 4.7 6.8e-17 61.2 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OAG03678.1 - 9.8e-17 61.5 0.0 2.3e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 OAG03678.1 - 3.1e-06 27.0 0.0 7.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAG03678.1 - 0.025 14.0 0.1 0.051 13.0 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pil1 PF13805.6 OAG03679.1 - 9.3e-103 343.3 8.3 1.1e-102 343.1 8.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 OAG03679.1 - 1.6 9.2 10.8 3.2 8.3 7.6 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Catalase PF00199.19 OAG03680.1 - 1.6e-165 550.9 0.1 2.1e-165 550.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 OAG03680.1 - 1.9e-42 144.5 0.1 4.3e-42 143.3 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 OAG03680.1 - 6.8e-14 51.8 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Bax1-I PF01027.20 OAG03681.1 - 0.002 18.0 0.4 0.0027 17.5 0.4 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DPBB_1 PF03330.18 OAG03681.1 - 0.01 16.1 0.2 0.043 14.1 0.1 2.1 2 0 0 2 2 2 0 Lytic transglycolase KR PF08659.10 OAG03683.1 - 3.9e-60 202.9 0.1 8.5e-60 201.7 0.1 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 OAG03683.1 - 2e-59 201.2 0.1 6.1e-59 199.7 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 OAG03683.1 - 8e-57 192.7 0.3 2e-56 191.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG03683.1 - 9.5e-56 189.6 0.0 1.6e-55 188.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG03683.1 - 8.6e-35 119.3 0.1 2.1e-34 118.0 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAG03683.1 - 1.7e-23 83.2 0.0 5.1e-23 81.7 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 OAG03683.1 - 8.5e-22 77.8 0.0 2.2e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 OAG03683.1 - 1.1e-17 65.4 0.0 1e-15 59.0 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 OAG03683.1 - 2.7e-16 59.9 0.0 6.9e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 OAG03683.1 - 3.6e-15 56.1 0.0 5.2e-14 52.4 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAG03683.1 - 1.2e-11 45.2 0.0 5.6e-11 43.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG03683.1 - 3.3e-10 40.5 0.0 1.7e-09 38.2 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG03683.1 - 7.5e-10 38.8 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OAG03683.1 - 3.9e-09 36.2 0.1 8.2e-08 31.9 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase Ubie_methyltran PF01209.18 OAG03683.1 - 1.3e-05 24.7 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 OAG03683.1 - 9.5e-05 22.7 0.1 0.00026 21.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_24 PF13578.6 OAG03683.1 - 0.00031 21.7 0.0 0.03 15.3 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain ADH_N PF08240.12 OAG03683.1 - 0.00035 20.4 0.1 0.00096 19.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 OAG03683.1 - 0.022 14.1 4.4 0.19 11.1 0.4 2.4 2 0 0 2 2 2 0 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 OAG03683.1 - 0.11 12.3 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase ACP_syn_III PF08545.10 OAG03683.1 - 0.12 12.2 0.5 0.38 10.6 0.5 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.16 OAG03684.1 - 1.1e-47 162.7 45.9 1.1e-47 162.7 45.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG03684.1 - 7.5e-24 84.1 14.1 1.4e-23 83.2 14.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG03684.1 - 1.8e-13 50.2 9.5 1.8e-13 50.2 9.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 OAG03684.1 - 0.011 16.0 0.3 0.011 16.0 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) DUF4632 PF15451.6 OAG03684.1 - 0.17 12.0 0.2 0.41 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Thioredoxin PF00085.20 OAG03685.1 - 6.8e-22 77.4 0.1 7.9e-22 77.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAG03685.1 - 1.3e-06 28.9 0.3 1.9e-05 25.1 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OAG03685.1 - 5.2e-05 23.2 0.1 7.2e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 OAG03685.1 - 5.2e-05 23.0 0.0 6.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG03685.1 - 0.00046 19.6 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAG03685.1 - 0.00062 20.0 0.0 0.39 11.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_5 PF13743.6 OAG03685.1 - 0.0036 17.0 0.1 0.12 12.1 0.0 2.1 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_4 PF13462.6 OAG03685.1 - 0.012 15.8 0.5 3.2 7.9 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin HyaE PF07449.11 OAG03685.1 - 0.014 15.3 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF2997 PF11211.8 OAG03685.1 - 0.026 14.3 0.1 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) AhpC-TSA PF00578.21 OAG03685.1 - 0.038 13.9 0.1 0.086 12.8 0.1 1.7 1 1 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 OAG03685.1 - 0.14 12.4 0.4 0.32 11.3 0.3 1.8 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.6 OAG03685.1 - 0.25 11.5 0.8 0.73 10.0 0.8 1.7 1 1 0 1 1 1 0 Thioredoxin-like Perilipin PF03036.16 OAG03686.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.6 1 1 1 2 2 2 0 Perilipin family Ribosomal_L27e PF01777.18 OAG03687.1 - 9.6e-37 125.2 9.0 1.3e-36 124.8 9.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OAG03687.1 - 0.00035 20.4 1.9 0.00043 20.1 0.2 2.0 2 0 0 2 2 2 1 KOW motif Sof1 PF04158.14 OAG03688.1 - 6.3e-31 106.5 19.6 1e-30 105.8 18.6 1.9 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.32 OAG03688.1 - 2.6e-28 97.7 6.0 5.3e-07 30.2 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG03688.1 - 1.4e-14 54.2 0.8 0.00085 19.6 0.0 4.5 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OAG03688.1 - 0.00058 18.3 0.0 1.2 7.4 0.0 2.9 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 OAG03688.1 - 0.025 15.1 0.0 31 5.2 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain Ge1_WD40 PF16529.5 OAG03688.1 - 0.025 13.5 0.0 0.47 9.4 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 OAG03688.1 - 0.052 12.5 0.0 0.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Abhydrolase_6 PF12697.7 OAG03689.1 - 4.7e-15 56.8 0.8 6.4e-15 56.3 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG03689.1 - 4.8e-11 42.8 0.0 9.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAG03689.1 - 0.084 11.8 0.0 0.17 10.7 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Glyco_hydro_71 PF03659.14 OAG03690.1 - 1.9e-73 247.5 0.4 2.3e-73 247.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PC4 PF02229.16 OAG03691.1 - 2e-23 81.7 0.0 3.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) 4HBT PF03061.22 OAG03692.1 - 0.00037 20.8 0.1 0.00093 19.5 0.1 1.8 1 0 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.16 OAG03693.1 - 1.2e-21 77.1 31.1 1.8e-21 76.5 31.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03693.1 - 2.8e-05 23.2 18.7 5.3e-05 22.3 18.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Apolipoprotein PF01442.18 OAG03694.1 - 0.00033 20.6 0.0 0.00072 19.5 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin PF05597.11 OAG03694.1 - 0.0025 17.8 1.0 0.29 11.1 0.1 2.9 1 1 1 2 2 2 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 OAG03694.1 - 0.012 15.6 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Perilipin PF03036.16 OAG03694.1 - 0.19 10.8 1.8 0.3 10.1 1.8 1.2 1 0 0 1 1 1 0 Perilipin family DUF1664 PF07889.12 OAG03694.1 - 0.34 11.0 1.0 0.7 9.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Mg_trans_NIPA PF05653.14 OAG03699.1 - 2.3e-92 309.3 30.1 2.9e-92 308.9 30.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAG03699.1 - 7.1e-05 23.0 6.6 7.1e-05 23.0 6.6 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF5362 PF17319.2 OAG03699.1 - 0.044 13.6 0.2 0.044 13.6 0.2 3.8 3 1 0 4 4 4 0 Family of unknown function (DUF5362) TMEM40 PF15817.5 OAG03699.1 - 1.4 8.7 3.7 15 5.3 1.5 2.6 2 0 0 2 2 2 0 Transmembrane protein 40 family COG4 PF08318.12 OAG03700.1 - 7.3e-122 406.6 0.0 9.6e-122 406.2 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein Glyco_hydro_61 PF03443.14 OAG03702.1 - 6.3e-54 183.0 0.0 7.1e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RAP1 PF07218.11 OAG03704.1 - 0.69 8.1 15.0 0.79 7.9 15.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 OAG03704.1 - 2 6.9 5.3 2.2 6.7 5.3 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OAG03704.1 - 2.3 7.8 16.2 2.7 7.5 16.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 OAG03704.1 - 3.2 7.8 5.9 3.8 7.5 5.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein FAP PF07174.11 OAG03705.1 - 0.11 12.0 7.5 0.13 11.7 7.5 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Glyco_hydro_125 PF06824.11 OAG03706.1 - 4.5e-161 536.4 0.2 5.4e-161 536.1 0.2 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) zf-RING_2 PF13639.6 OAG03707.1 - 0.023 15.0 3.8 0.023 15.0 3.8 2.1 2 0 0 2 2 2 0 Ring finger domain zf-ribbon_3 PF13248.6 OAG03707.1 - 0.057 12.9 1.5 0.15 11.6 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain SKG6 PF08693.10 OAG03708.1 - 0.0016 17.8 0.7 0.0024 17.2 0.7 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 OAG03708.1 - 0.031 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OAG03708.1 - 0.039 14.8 0.0 0.051 14.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 OAG03708.1 - 0.1 12.7 1.2 0.18 11.9 1.2 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) RSN1_TM PF13967.6 OAG03708.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport CD34_antigen PF06365.12 OAG03708.1 - 0.14 11.7 0.1 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family YajC PF02699.15 OAG03708.1 - 0.25 11.2 0.1 0.43 10.5 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit PRIMA1 PF16101.5 OAG03708.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.6 2 2 1 3 3 3 0 Proline-rich membrane anchor 1 Hydrophobin_2 PF06766.11 OAG03709.1 - 7.4e-23 80.3 11.4 1e-22 79.8 11.4 1.2 1 0 0 1 1 1 1 Fungal hydrophobin AA_permease PF00324.21 OAG03710.1 - 6.6e-134 447.1 46.0 8.2e-134 446.8 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG03710.1 - 2.1e-35 122.4 49.0 2.8e-35 122.0 49.0 1.1 1 0 0 1 1 1 1 Amino acid permease TssO PF17561.2 OAG03710.1 - 0.29 11.2 1.6 0.91 9.6 0.2 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO TPR_10 PF13374.6 OAG03713.1 - 7.9e-49 162.3 18.6 1.3e-11 44.0 0.0 7.6 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAG03713.1 - 3.7e-36 123.3 10.2 2.5e-13 50.1 0.2 6.0 3 1 3 6 6 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG03713.1 - 1.6e-12 46.5 3.4 0.14 12.3 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat HET PF06985.11 OAG03713.1 - 1.4e-11 45.0 5.8 1.3e-08 35.3 0.2 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_MalT PF17874.1 OAG03713.1 - 3.6e-10 39.7 8.9 1.8e-06 27.5 2.8 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 OAG03713.1 - 4.9e-10 38.8 0.2 0.43 10.5 0.0 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 OAG03713.1 - 1e-09 38.0 3.7 0.14 12.8 0.0 5.7 5 0 0 5 5 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAG03713.1 - 6.2e-08 32.1 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 OAG03713.1 - 4.8e-07 29.8 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.6 OAG03713.1 - 2.7e-06 27.2 1.3 0.75 10.2 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat IstB_IS21 PF01695.17 OAG03713.1 - 2.6e-05 24.0 0.3 0.00014 21.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 OAG03713.1 - 5.1e-05 23.7 0.2 0.00031 21.2 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.6 OAG03713.1 - 0.00032 21.3 2.2 5.7 7.7 0.0 4.8 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG03713.1 - 0.00034 21.2 4.4 1.4 9.9 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG03713.1 - 0.0012 18.8 14.5 12 6.3 0.0 6.6 8 0 0 8 8 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 OAG03713.1 - 0.0018 18.6 0.1 0.0071 16.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain TPR_19 PF14559.6 OAG03713.1 - 0.0051 17.3 1.0 3.2 8.3 0.0 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TniB PF05621.11 OAG03713.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein DUF4919 PF16266.5 OAG03713.1 - 0.023 14.6 0.5 6.7 6.6 0.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4919) ATPase_2 PF01637.18 OAG03713.1 - 0.036 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OAG03713.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG03713.1 - 0.083 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG03713.1 - 0.086 12.8 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAG03713.1 - 0.096 12.9 0.1 0.78 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MAAL_C PF07476.11 OAG03713.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus AAA PF00004.29 OAG03713.1 - 0.11 12.9 0.0 0.37 11.2 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG03713.1 - 0.16 12.4 0.0 0.61 10.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase TPR_17 PF13431.6 OAG03713.1 - 1.2 9.7 13.5 7 7.3 0.1 5.0 7 0 0 7 7 3 0 Tetratricopeptide repeat PPR PF01535.20 OAG03713.1 - 1.8 9.0 4.3 46 4.6 0.1 3.4 4 0 0 4 4 2 0 PPR repeat Abhydrolase_1 PF00561.20 OAG03714.1 - 2.9e-27 95.9 0.0 1.1e-26 94.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG03714.1 - 4.5e-13 49.0 0.0 2e-12 46.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG03714.1 - 3.2e-10 41.0 0.0 4.2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG03714.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Cutinase PF01083.22 OAG03715.1 - 1.1e-45 155.8 1.0 1.3e-45 155.5 1.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG03715.1 - 3.7e-07 29.9 0.6 8.1e-07 28.8 0.2 1.7 2 0 0 2 2 2 1 PE-PPE domain Palm_thioest PF02089.15 OAG03715.1 - 0.00084 19.3 0.0 0.00096 19.1 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 OAG03715.1 - 0.0028 17.5 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) VirJ PF06057.11 OAG03715.1 - 0.041 13.8 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 OAG03715.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 OAG03715.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain PXA PF02194.15 OAG03717.1 - 2.2e-29 102.7 0.1 2.2e-29 102.7 0.1 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 OAG03717.1 - 9.9e-22 77.6 1.2 2.1e-21 76.6 0.1 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 OAG03717.1 - 1e-05 25.4 0.0 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 1 PX domain G0-G1_switch_2 PF15103.6 OAG03717.1 - 0.38 11.2 5.8 0.52 10.8 0.0 3.0 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF1635 PF07795.11 OAG03717.1 - 5.8 6.7 17.1 0.021 14.7 7.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) 4HBT PF03061.22 OAG03718.1 - 5.6e-12 45.8 0.8 7.4e-12 45.5 0.2 1.5 2 0 0 2 2 2 1 Thioesterase superfamily SnoaL_2 PF12680.7 OAG03718.1 - 0.034 14.8 0.1 0.053 14.2 0.1 1.5 1 1 0 1 1 1 0 SnoaL-like domain DUF4442 PF14539.6 OAG03718.1 - 0.09 12.9 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) CutC PF03932.14 OAG03722.1 - 8.8e-57 191.9 0.0 1e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 CutC family B12-binding PF02310.19 OAG03722.1 - 0.087 12.9 0.0 0.94 9.5 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain DUF3176 PF11374.8 OAG03723.1 - 3.7e-24 85.0 0.1 3.7e-24 85.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) TPPK_C PF12555.8 OAG03723.1 - 0.83 9.8 6.8 1.8 8.7 0.6 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Ribosomal_S30 PF04758.14 OAG03725.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S30 Gti1_Pac2 PF09729.9 OAG03726.1 - 2.1e-45 155.1 3.1 1.8e-38 132.4 0.1 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family MFS_1 PF07690.16 OAG03727.1 - 2.2e-35 122.2 26.5 2.2e-35 122.2 26.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1230 PF06799.11 OAG03727.1 - 0.2 11.7 0.6 4.1 7.5 0.0 2.8 2 1 1 3 3 3 0 Conserved in the green lineage and diatoms 27 AAA_23 PF13476.6 OAG03728.1 - 0.2 12.1 3.7 0.33 11.4 3.7 1.3 1 0 0 1 1 1 0 AAA domain XRCC4 PF06632.12 OAG03728.1 - 0.7 8.7 10.7 1.1 8.1 10.7 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pannexin_like PF12534.8 OAG03728.1 - 1 8.4 2.4 1.5 7.8 2.4 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Band_7 PF01145.25 OAG03730.1 - 1.1e-15 58.0 0.1 1.1e-15 58.0 0.1 2.8 2 1 0 2 2 2 1 SPFH domain / Band 7 family DUF5446 PF17522.2 OAG03730.1 - 5.3 7.3 7.0 2.1 8.6 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Mago-bind PF09282.10 OAG03732.1 - 2.5e-15 56.0 3.5 4.9e-15 55.1 3.5 1.5 1 0 0 1 1 1 1 Mago binding GET2 PF08690.10 OAG03732.1 - 0.061 13.0 3.1 0.079 12.6 3.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 MDM10 PF12519.8 OAG03732.1 - 6.8 5.4 5.4 8.8 5.1 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 UCR_UQCRX_QCR9 PF05365.12 OAG03733.1 - 4.3e-25 87.4 2.2 4.9e-25 87.2 2.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Saf_2TM PF18303.1 OAG03733.1 - 0.11 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain zf-UBR PF02207.20 OAG03734.1 - 7.6e-19 67.7 13.3 7.6e-19 67.7 13.3 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OAG03734.1 - 0.00029 20.5 0.1 0.00076 19.2 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 OAG03734.1 - 0.022 15.1 0.8 0.022 15.1 0.8 3.6 4 1 0 4 4 4 0 Ring finger domain Band_7 PF01145.25 OAG03736.1 - 1.2e-29 103.6 4.6 1.6e-29 103.1 4.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OAG03736.1 - 0.0037 17.0 0.4 0.0069 16.1 0.3 1.4 1 1 0 1 1 1 1 SPFH domain-Band 7 family Mito_carr PF00153.27 OAG03737.1 - 3.9e-73 241.5 3.7 1.3e-24 85.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG03737.1 - 0.00025 20.3 3.1 0.1 11.7 0.0 3.7 3 1 1 4 4 4 2 Gammaproteobacterial serine protease GAD-like PF08887.11 OAG03737.1 - 0.017 14.9 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 GAD-like domain PT-VENN PF04829.13 OAG03737.1 - 0.68 10.1 4.9 3.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Acetyltransf_1 PF00583.25 OAG03738.1 - 2e-19 70.0 0.0 2.7e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG03738.1 - 1.2e-10 41.4 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG03738.1 - 1.4e-10 41.4 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG03738.1 - 1.5e-09 37.7 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAG03738.1 - 7.6e-09 36.4 0.0 1e-08 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAG03738.1 - 3.3e-05 23.6 0.0 5.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG03738.1 - 9e-05 22.6 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG03738.1 - 0.004 17.3 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 OAG03738.1 - 0.056 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase LCAT PF02450.15 OAG03739.1 - 5.8e-104 348.4 0.0 6.8e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase 2OG-FeII_Oxy_2 PF13532.6 OAG03740.1 - 7.4e-15 55.6 0.0 1.2e-14 55.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OAG03740.1 - 0.00064 20.2 0.1 0.002 18.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WSC PF01822.19 OAG03741.1 - 3e-31 107.4 15.9 2.5e-19 69.3 8.0 2.1 2 0 0 2 2 2 2 WSC domain Pkinase PF00069.25 OAG03744.1 - 1.3e-39 136.1 0.6 4.5e-27 95.1 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03744.1 - 3.5e-16 59.3 0.1 1.5e-14 53.9 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAG03744.1 - 0.0029 17.6 0.2 0.0073 16.2 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAG03744.1 - 0.0048 15.9 0.0 0.0071 15.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 OAG03744.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OAG03744.1 - 0.022 13.7 0.2 0.033 13.1 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Zn_clus PF00172.18 OAG03748.1 - 5.4e-09 36.0 13.1 1e-08 35.1 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG03748.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain p450 PF00067.22 OAG03750.1 - 2.9e-45 154.9 0.0 1.1e-44 152.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Glyco_transf_24 PF18404.1 OAG03751.1 - 2e-146 486.4 1.4 3.3e-146 485.8 1.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OAG03751.1 - 1.1e-71 241.8 0.1 6.4e-69 232.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_15 PF18403.1 OAG03751.1 - 1.4e-57 195.1 0.6 6.3e-56 189.7 0.4 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OAG03751.1 - 3e-49 167.5 0.1 9.7e-49 165.8 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OAG03751.1 - 1.2e-46 158.0 0.1 5e-44 149.5 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OAG03751.1 - 3.1e-39 133.4 0.0 6.2e-39 132.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 OAG03751.1 - 4.3e-05 23.2 0.3 9.6e-05 22.0 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Esterase_phd PF10503.9 OAG03752.1 - 2.8e-05 23.7 0.1 0.00027 20.5 0.1 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG03752.1 - 0.00018 21.1 0.1 0.00066 19.2 0.0 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 OAG03752.1 - 0.0019 16.9 0.0 0.0089 14.7 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) PNRC PF15365.6 OAG03752.1 - 0.0075 16.1 1.0 0.024 14.4 1.0 1.9 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif Abhydrolase_2 PF02230.16 OAG03752.1 - 0.017 14.9 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 OAG03753.1 - 2.5e-12 46.4 40.5 2.5e-12 46.4 40.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAG03753.1 - 0.00043 18.7 1.5 0.00043 18.7 1.5 2.2 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Gcn1_N PF12074.8 OAG03754.1 - 3.2e-120 401.7 11.9 3.7e-120 401.5 6.9 3.9 4 1 1 5 5 5 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 OAG03754.1 - 4.8e-33 110.4 36.6 0.012 15.8 0.2 21.5 25 0 0 25 25 22 10 HEAT repeat HEAT_EZ PF13513.6 OAG03754.1 - 7.7e-30 102.9 57.6 1.4e-06 28.6 0.0 21.3 17 3 6 23 23 21 9 HEAT-like repeat HEAT_2 PF13646.6 OAG03754.1 - 1.6e-24 86.1 54.8 3.8e-06 27.2 0.0 16.2 11 4 9 21 21 21 9 HEAT repeats Cnd1 PF12717.7 OAG03754.1 - 1.2e-16 61.2 6.2 0.02 14.9 0.0 10.1 9 2 1 10 10 10 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAG03754.1 - 2.4e-13 50.5 0.0 0.7 10.5 0.0 9.4 7 3 1 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAG03754.1 - 4.3e-11 42.8 0.0 0.032 13.8 0.0 6.9 5 2 1 6 6 6 3 CLASP N terminal ParcG PF10274.9 OAG03754.1 - 5.4e-11 42.9 8.1 0.0005 20.2 0.1 7.5 8 0 0 8 8 8 3 Parkin co-regulated protein Adaptin_N PF01602.20 OAG03754.1 - 7.9e-08 31.3 8.0 0.046 12.3 0.2 7.0 6 2 0 6 6 6 2 Adaptin N terminal region TIP120 PF08623.10 OAG03754.1 - 4.2e-07 29.9 1.9 0.0091 15.8 0.0 6.7 6 1 1 7 7 7 1 TATA-binding protein interacting (TIP20) UME PF08064.13 OAG03754.1 - 3.8e-05 23.5 4.4 2.6 8.0 0.0 7.9 6 3 2 9 9 8 1 UME (NUC010) domain RTP1_C1 PF10363.9 OAG03754.1 - 0.00034 20.8 11.0 19 5.5 0.0 8.3 8 0 0 8 8 8 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 OAG03754.1 - 0.00063 19.0 25.4 0.0014 17.8 0.2 7.4 6 1 2 8 8 8 2 RNAPII transcription regulator C-terminal FANCI_S2 PF14676.6 OAG03754.1 - 0.018 15.4 3.9 3.6 7.9 0.2 4.2 3 1 0 3 3 3 0 FANCI solenoid 2 Ecm29 PF13001.7 OAG03754.1 - 0.027 13.2 7.7 3.3 6.3 0.0 5.2 4 2 0 5 5 5 0 Proteasome stabiliser TFCD_C PF12612.8 OAG03754.1 - 0.043 13.6 1.8 1.3 8.8 0.0 4.1 5 1 0 5 5 3 0 Tubulin folding cofactor D C terminal RIX1 PF08167.12 OAG03754.1 - 0.098 12.4 4.1 2.3 7.9 0.4 4.7 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis RasGEF_N_2 PF14663.6 OAG03754.1 - 0.11 13.0 3.7 1.7 9.1 0.0 4.6 5 0 0 5 5 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3535 PF12054.8 OAG03754.1 - 0.24 10.6 4.2 4.8 6.3 0.0 4.2 4 2 1 5 5 5 0 Domain of unknown function (DUF3535) HEAT_PBS PF03130.16 OAG03754.1 - 0.7 10.7 15.1 35 5.5 0.2 8.6 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat DUF3384 PF11864.8 OAG03754.1 - 0.79 8.6 4.3 2.7 6.8 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3384) Cohesin_HEAT PF12765.7 OAG03754.1 - 1.8 9.0 13.9 11 6.4 0.0 6.1 8 0 0 8 8 5 0 HEAT repeat associated with sister chromatid cohesion U3snoRNP10 PF12397.8 OAG03754.1 - 2.2 8.6 10.1 30 5.0 0.0 6.9 5 1 0 5 5 5 0 U3 small nucleolar RNA-associated protein 10 HA2 PF04408.23 OAG03755.1 - 7.2e-16 58.4 0.0 2.9e-15 56.5 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG03755.1 - 1.7e-13 50.9 0.0 4.8e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG03755.1 - 6e-10 39.2 0.1 1.2e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG03755.1 - 9.1e-08 32.5 0.1 8.5e-07 29.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 OAG03755.1 - 0.00063 20.1 0.2 0.0017 18.7 0.2 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 OAG03755.1 - 0.0055 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG03755.1 - 0.044 14.3 0.1 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 OAG03755.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 OAG03755.1 - 0.18 11.1 1.2 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.6 OAG03755.1 - 0.61 10.6 2.6 1.3 9.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain SAGA-Tad1 PF12767.7 OAG03756.1 - 7.1e-56 189.6 0.0 9.1e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Glyco_hydro_43 PF04616.14 OAG03758.1 - 7.2e-74 248.7 0.1 9.3e-74 248.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG03758.1 - 3e-25 89.1 0.0 4.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain HET PF06985.11 OAG03759.1 - 4.4e-27 95.2 0.0 1.1e-26 93.9 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG03761.1 - 3.8e-09 37.0 1.4 4.9e-09 36.7 1.4 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.6 OAG03762.1 - 1.7e-46 154.8 6.7 2.1e-13 49.6 0.0 6.1 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAG03762.1 - 1.5e-39 134.1 1.1 1.3e-13 51.0 0.0 4.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG03762.1 - 1.9e-15 55.7 0.5 0.00015 21.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG03762.1 - 2.3e-08 33.5 3.3 0.44 10.8 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG03762.1 - 2.4e-08 33.5 0.6 0.21 11.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAG03762.1 - 2.7e-07 31.0 0.0 0.0015 19.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG03762.1 - 1.5e-06 28.8 0.0 0.44 11.2 0.0 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG03762.1 - 1.5e-06 28.2 0.6 0.2 12.1 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG03762.1 - 6.8e-06 25.9 1.2 8.4 6.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG03762.1 - 4.2e-05 23.8 0.0 3.5 8.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG03762.1 - 6.9e-05 22.4 1.1 0.034 13.5 0.0 2.8 1 1 1 2 2 2 1 MalT-like TPR region TPR_5 PF12688.7 OAG03762.1 - 0.00071 19.8 0.2 0.52 10.6 0.0 3.0 1 1 2 3 3 3 1 Tetratrico peptide repeat TPR_14 PF13428.6 OAG03762.1 - 0.0021 18.7 0.6 21 6.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 OAG03762.1 - 0.003 17.7 1.0 4.6 7.7 0.2 3.5 3 0 0 3 3 3 1 PPR repeat ANAPC3 PF12895.7 OAG03762.1 - 0.0032 17.7 0.1 11 6.3 0.0 3.3 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Metallophos_3 PF14582.6 OAG03762.1 - 0.0071 15.7 0.0 2.3 7.5 0.0 2.2 1 1 1 2 2 2 2 Metallophosphoesterase, calcineurin superfamily TPR_3 PF07720.12 OAG03762.1 - 0.022 14.7 0.0 4.6 7.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MazG PF03819.17 OAG03762.1 - 0.028 14.6 0.3 17 5.6 0.0 3.1 1 1 1 3 3 3 0 MazG nucleotide pyrophosphohydrolase domain CutA1 PF03091.15 OAG03762.1 - 0.029 14.2 0.1 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein DUF1897 PF09005.10 OAG03762.1 - 0.058 12.9 0.2 10 5.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) TPP_enzyme_M PF00205.22 OAG03762.1 - 0.082 12.6 0.0 2.6 7.8 0.0 2.2 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TPR_6 PF13174.6 OAG03762.1 - 0.11 13.2 0.7 94 4.0 0.1 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.7 OAG03762.1 - 0.58 9.9 2.7 22 4.9 0.0 3.5 4 0 0 4 4 4 0 PPR repeat OST3_OST6 PF04756.13 OAG03763.1 - 5.3e-105 351.0 0.0 6.4e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 OAG03763.1 - 0.033 15.0 1.2 0.065 14.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Sec20 PF03908.13 OAG03764.1 - 0.02 14.8 0.8 0.02 14.8 0.8 3.3 2 1 1 3 3 3 0 Sec20 DUF1310 PF07006.11 OAG03765.1 - 0.068 13.2 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) p450 PF00067.22 OAG03766.1 - 7.1e-71 239.3 0.0 9.9e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 OAG03767.1 - 8e-10 38.1 0.1 1.8e-06 27.1 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03767.1 - 6.5e-07 29.4 9.5 1.2e-06 28.5 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDZ_1 PF12812.7 OAG03768.1 - 3.4e-56 187.2 0.0 1.4e-34 118.0 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 OAG03768.1 - 1.4e-24 87.7 0.9 3.6e-21 76.6 0.1 2.8 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 OAG03768.1 - 3.4e-14 52.4 0.4 1.9e-06 27.6 0.4 4.6 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 OAG03768.1 - 8.9e-13 48.4 1.2 2e-07 31.2 0.4 4.1 5 0 0 5 5 5 2 PDZ domain PDZ PF00595.24 OAG03768.1 - 3.5e-12 46.5 0.0 8.9e-07 29.2 0.0 3.7 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 OAG03768.1 - 0.014 15.3 0.6 0.17 11.9 0.2 3.0 4 0 0 4 4 4 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 OAG03768.1 - 0.05 12.2 0.1 0.09 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 OAG03768.1 - 0.078 12.8 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Zn_clus PF00172.18 OAG03769.1 - 1e-07 32.0 6.6 1e-07 32.0 6.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ParD PF09386.10 OAG03769.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Antitoxin ParD p450 PF00067.22 OAG03770.1 - 5.8e-57 193.5 0.0 8.7e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 OAG03771.1 - 1.6e-21 76.7 12.0 1.6e-21 76.7 12.0 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family CN_hydrolase PF00795.22 OAG03772.1 - 9.4e-35 120.2 0.0 1.6e-34 119.4 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase YhcG_C PF06250.11 OAG03772.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 YhcG PDDEXK nuclease domain Peptidase_S24 PF00717.23 OAG03775.1 - 3.1e-08 33.4 0.1 4.6e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like MFS_1 PF07690.16 OAG03776.1 - 5e-27 94.8 36.2 1.5e-15 57.0 8.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03776.1 - 1.5e-05 24.0 3.0 1.5e-05 24.0 3.0 3.2 3 1 1 4 4 4 1 Sugar (and other) transporter COX14 PF14880.6 OAG03777.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Gram_pos_anchor PF00746.21 OAG03777.1 - 8.8 6.4 7.5 27 4.8 2.6 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Syja_N PF02383.18 OAG03782.1 - 3.6e-92 309.1 0.0 5.4e-92 308.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 OAG03782.1 - 2.3e-32 111.1 0.0 4.6e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Sugar_tr PF00083.24 OAG03783.1 - 1.5e-114 383.3 18.8 1.8e-114 383.1 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG03783.1 - 1.5e-28 99.8 26.6 1.1e-27 96.9 15.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG03783.1 - 0.00013 20.6 0.6 0.00013 20.6 0.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 OAG03783.1 - 0.00021 20.3 0.8 0.00048 19.1 0.8 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM HET PF06985.11 OAG03784.1 - 5.2e-31 108.0 0.3 1e-30 107.0 0.3 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 OAG03784.1 - 0.39 10.8 9.4 0.096 12.8 5.0 2.2 2 0 0 2 2 2 0 WW domain Ribosomal_S17e PF00833.18 OAG03787.1 - 1.8e-59 199.0 0.2 2.2e-59 198.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S17 Na_Ca_ex PF01699.24 OAG03788.1 - 1.5e-29 103.0 29.4 2.7e-15 56.6 11.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hydro_1 PF00232.18 OAG03789.1 - 3.3e-71 240.1 1.0 3e-68 230.3 1.0 2.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 OAG03789.1 - 0.00033 20.2 0.1 0.0054 16.2 0.0 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) GMC_oxred_N PF00732.19 OAG03790.1 - 4.4e-49 167.5 0.4 7.9e-49 166.6 0.4 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG03790.1 - 1.2e-24 87.5 0.1 4.7e-24 85.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG03790.1 - 1.8e-07 30.6 2.4 4.7e-06 25.9 1.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG03790.1 - 1.4e-05 24.5 0.3 6.2e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG03790.1 - 0.00011 21.6 0.1 0.00017 20.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG03790.1 - 0.00011 22.3 0.2 0.0004 20.6 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG03790.1 - 0.00068 19.0 0.1 0.0034 16.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 OAG03790.1 - 0.003 16.9 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG03790.1 - 0.0041 15.9 0.3 0.0067 15.2 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 OAG03790.1 - 0.011 15.1 0.6 0.019 14.4 0.6 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG03790.1 - 0.05 14.2 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG03790.1 - 0.11 11.6 0.3 0.77 8.8 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.21 OAG03790.1 - 0.16 11.3 0.1 1 8.7 0.1 2.0 2 0 0 2 2 2 0 ThiF family DAO PF01266.24 OAG03790.1 - 0.16 11.5 7.2 1.6 8.3 7.3 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAG03790.1 - 0.2 11.2 0.6 0.36 10.4 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FYVE PF01363.21 OAG03791.1 - 1.3e-13 50.9 12.0 2.2e-13 50.1 12.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 OAG03791.1 - 2.8 8.2 15.7 0.58 10.4 10.2 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger IBR PF01485.21 OAG03791.1 - 9.9 6.5 11.6 1.6 9.0 6.4 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Dus PF01207.17 OAG03792.1 - 1.1e-59 202.1 0.0 8.2e-58 195.9 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 OAG03792.1 - 0.019 14.2 0.0 0.072 12.3 0.0 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase DnaJ PF00226.31 OAG03793.1 - 1.8e-10 40.8 0.0 2e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain Presenilin PF01080.17 OAG03794.1 - 0.49 9.1 11.0 0.53 9.0 11.0 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 OAG03794.1 - 0.53 9.2 6.9 0.59 9.1 6.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2151 PF10221.9 OAG03794.1 - 1.6 7.3 9.8 1.9 7.0 9.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator MRP-S26 PF14943.6 OAG03794.1 - 1.8 8.5 22.2 2.9 7.8 22.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Hid1 PF12722.7 OAG03794.1 - 2 6.4 11.2 2.3 6.2 11.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PGA2 PF07543.12 OAG03794.1 - 2.7 8.0 23.8 4.3 7.3 23.8 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF5308 PF17233.2 OAG03794.1 - 8.2 6.6 10.5 86 3.3 10.5 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5308) Asp-B-Hydro_N PF05279.11 OAG03794.1 - 8.5 6.4 17.7 11 6.1 17.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4746 PF15928.5 OAG03794.1 - 9 5.6 13.5 11 5.4 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 OAG03794.1 - 9 6.0 20.2 10 5.8 19.6 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cu-oxidase_3 PF07732.15 OAG03795.1 - 2.1e-41 140.7 4.9 2.6e-41 140.3 1.3 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG03795.1 - 1.1e-40 138.6 8.4 4.6e-36 123.6 0.7 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG03795.1 - 2.7e-32 112.1 1.2 3.2e-32 111.8 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Acetyltransf_1 PF00583.25 OAG03796.1 - 0.00015 22.0 0.0 0.0004 20.6 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG03796.1 - 0.0018 18.2 0.0 0.025 14.5 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 OAG03796.1 - 0.0042 17.8 0.0 0.1 13.3 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG03796.1 - 0.071 13.5 0.0 0.16 12.4 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Rhodanese_C PF12368.8 OAG03797.1 - 0.069 13.5 0.3 0.14 12.5 0.3 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Ribosomal_L37e PF01907.19 OAG03797.1 - 2.2 8.5 5.5 25 5.1 0.4 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e ENOD40 PF08247.11 OAG03797.1 - 2.7 8.2 4.0 35 4.7 0.4 2.5 2 0 0 2 2 2 0 ENOD40 protein Ribosomal_S13 PF00416.22 OAG03798.1 - 1.5e-53 180.6 2.3 1.8e-53 180.4 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 OAG03798.1 - 0.018 13.8 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 OAG03798.1 - 0.14 12.6 0.2 0.29 11.6 0.2 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Pkinase PF00069.25 OAG03799.1 - 1.2e-38 133.0 0.0 1.6e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03799.1 - 5.3e-17 61.9 0.0 7.2e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase INTS5_C PF14838.6 OAG03799.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Peptidase_S10 PF00450.22 OAG03800.1 - 9.8e-126 420.5 1.7 1.2e-125 420.3 1.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 OAG03800.1 - 4.5e-16 59.5 1.5 1.3e-15 58.0 1.5 1.8 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide SBDS_C PF09377.10 OAG03801.1 - 1e-34 119.0 0.6 1e-34 119.0 0.6 1.8 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 OAG03801.1 - 1.4e-29 102.0 2.0 3.2e-29 100.8 2.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HARE-HTH PF05066.13 OAG03801.1 - 0.063 13.7 0.1 0.17 12.3 0.1 1.8 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain SPAR_C PF11881.8 OAG03802.1 - 0.0015 18.6 2.6 0.0019 18.2 2.6 1.2 1 0 0 1 1 1 1 C-terminal domain of SPAR protein Peptidase_S8 PF00082.22 OAG03803.1 - 3e-32 112.1 12.1 4.1e-32 111.7 12.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG03803.1 - 1e-16 61.4 0.1 2e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 RPE65 PF03055.15 OAG03804.1 - 1.1e-107 361.1 0.3 1.3e-107 360.9 0.3 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PAF-AH_p_II PF03403.13 OAG03805.1 - 0.00039 19.0 0.0 0.0022 16.6 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAG03805.1 - 0.0083 15.4 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAG03805.1 - 0.038 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 OAG03805.1 - 0.12 12.2 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3280 PF11684.8 OAG03806.1 - 0.011 16.1 0.8 0.011 16.1 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2380) ERM PF00769.19 OAG03806.1 - 0.051 13.4 22.4 0.07 12.9 22.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Draxin PF15550.6 OAG03806.1 - 0.5 10.2 11.3 0.66 9.8 11.3 1.1 1 0 0 1 1 1 0 Draxin Ribosomal_S7 PF00177.21 OAG03807.1 - 4.9e-37 126.9 1.9 6e-37 126.6 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CENP-F_leu_zip PF10473.9 OAG03808.1 - 0.00033 20.7 5.2 0.00033 20.7 5.2 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 OAG03808.1 - 0.025 14.8 7.4 1.1 9.4 1.1 2.7 1 1 1 2 2 2 0 Tropomyosin like DUF4672 PF15716.5 OAG03808.1 - 0.029 14.0 0.8 0.029 14.0 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4672) GAS PF13851.6 OAG03808.1 - 0.035 13.5 8.8 0.053 12.9 6.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding LPP PF04728.13 OAG03808.1 - 1.1 9.7 5.0 6.7 7.2 0.1 3.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 OAG03808.1 - 5.3 7.1 11.9 5.6 7.0 3.0 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein RTA1 PF04479.13 OAG03809.1 - 4.3e-64 215.9 7.3 4.3e-64 215.9 7.3 1.5 2 0 0 2 2 2 1 RTA1 like protein Orthoreo_P10 PF07204.11 OAG03809.1 - 0.12 12.4 2.7 9.3 6.3 0.1 2.6 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Zn_clus PF00172.18 OAG03810.1 - 2e-10 40.6 9.6 3.1e-10 40.0 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG03810.1 - 1.1e-09 37.6 0.5 1.6e-09 37.1 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pan3_PK PF18101.1 OAG03812.1 - 5.1e-55 185.2 0.1 1.7e-54 183.6 0.1 1.8 1 1 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 OAG03812.1 - 8.9e-06 25.3 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.24 OAG03812.1 - 0.012 15.5 1.2 0.022 14.6 1.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glyco_hydro_61 PF03443.14 OAG03813.1 - 5.2e-65 219.2 2.2 6.2e-65 219.0 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PD40 PF07676.12 OAG03814.1 - 8.4e-50 165.8 17.2 2.3e-08 33.8 0.5 9.7 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 OAG03814.1 - 1.9e-13 49.9 2.8 0.0007 18.4 0.5 6.3 4 2 1 5 5 5 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 OAG03814.1 - 0.024 14.6 1.3 8.1 6.4 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3748) DUF1513 PF07433.11 OAG03814.1 - 0.029 13.5 0.1 5 6.1 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1513) WD40 PF00400.32 OAG03814.1 - 0.25 12.3 5.8 47 5.1 0.0 5.4 7 0 0 7 7 7 0 WD domain, G-beta repeat Proteasome_A_N PF10584.9 OAG03814.1 - 3.5 7.4 16.0 89 2.9 0.1 7.0 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DUF4451 PF14616.6 OAG03815.1 - 6.3e-05 23.2 0.3 0.00012 22.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) FOXP-CC PF16159.5 OAG03815.1 - 0.19 12.4 0.4 22 5.8 0.1 2.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 OAG03815.1 - 0.19 12.3 15.5 3.6 8.2 0.5 4.8 4 1 0 4 4 4 0 Zinc finger, C2H2 type Lactamase_B_4 PF13691.6 OAG03818.1 - 1.2e-23 82.6 0.7 6.8e-23 80.1 0.3 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 OAG03818.1 - 2.5e-08 33.7 0.1 0.00093 18.8 0.0 2.8 2 0 0 2 2 2 2 Beta-lactamase superfamily domain bZIP_1 PF00170.21 OAG03818.1 - 1.2e-06 28.5 9.8 4.3e-06 26.7 9.8 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG03818.1 - 0.0033 17.5 7.6 0.0033 17.5 7.6 3.2 3 0 0 3 3 3 1 Basic region leucine zipper Lactamase_B PF00753.27 OAG03818.1 - 0.026 14.5 0.3 0.08 12.9 0.3 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily SprA-related PF12118.8 OAG03818.1 - 0.039 13.1 18.7 0.12 11.5 18.7 1.8 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 OAG03818.1 - 3 7.8 36.1 0.009 16.1 25.0 2.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit PPR_2 PF13041.6 OAG03819.1 - 9e-28 96.2 0.0 3.8e-08 33.4 0.0 6.2 6 1 1 7 7 7 4 PPR repeat family PPR_3 PF13812.6 OAG03819.1 - 2.9e-12 46.5 0.0 0.0014 18.6 0.0 5.4 4 1 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 OAG03819.1 - 1.1e-11 44.2 0.5 0.00068 19.7 0.2 5.4 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 OAG03819.1 - 2.2e-08 33.8 0.0 0.0037 16.7 0.0 3.4 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAG03819.1 - 8.5e-08 31.8 0.1 0.0047 16.6 0.0 4.6 4 1 0 4 4 4 2 PPR repeat RPM2 PF08579.11 OAG03819.1 - 0.22 11.9 0.0 3.9 7.9 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) His_Phos_2 PF00328.22 OAG03820.1 - 9.8e-17 61.4 0.0 3.6e-16 59.5 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TAF4 PF05236.14 OAG03821.1 - 2.7e-33 115.9 2.3 4.3e-26 92.3 0.8 2.4 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 OAG03822.1 - 3.5e-71 239.2 0.0 5.3e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OAG03822.1 - 3.1e-31 107.9 0.0 6.6e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 OAG03822.1 - 5.7e-20 72.2 0.2 1.1e-19 71.3 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OAG03822.1 - 7.5e-18 64.7 0.2 1.2e-17 64.0 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OAG03822.1 - 3.1e-12 46.2 0.0 7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OAG03822.1 - 3.7e-05 23.4 1.1 0.00023 20.7 0.4 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG03822.1 - 4.6e-05 23.4 0.0 0.00016 21.6 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Acetyltransf_4 PF13420.7 OAG03823.1 - 0.17 12.0 1.0 0.41 10.8 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Arf PF00025.21 OAG03824.1 - 1.3e-66 223.4 2.2 1.4e-66 223.3 2.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OAG03824.1 - 2.2e-13 50.1 0.1 2.5e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG03824.1 - 5.7e-13 49.2 0.1 8.1e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OAG03824.1 - 2.8e-12 46.5 1.4 4.3e-07 29.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OAG03824.1 - 5.3e-10 39.0 0.1 6.3e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG03824.1 - 2.5e-08 34.0 0.0 3.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG03824.1 - 1.6e-07 31.0 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OAG03824.1 - 0.00014 21.5 0.1 0.0035 16.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OAG03824.1 - 0.027 14.0 0.5 0.064 12.8 0.5 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B CN_hydrolase PF00795.22 OAG03824.1 - 0.045 13.1 0.0 0.084 12.2 0.0 1.3 2 0 0 2 2 2 0 Carbon-nitrogen hydrolase 6PF2K PF01591.18 OAG03824.1 - 0.065 12.5 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase CdhD PF03599.16 OAG03824.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit NTPase_1 PF03266.15 OAG03824.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 1 0 1 1 1 0 NTPase DUF4045 PF13254.6 OAG03825.1 - 6.1e-115 385.2 49.2 6.1e-115 385.2 49.2 5.1 3 2 1 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 OAG03825.1 - 2.6e-05 24.0 0.0 0.027 14.4 0.0 3.5 3 0 0 3 3 3 1 Gelsolin repeat HIGH_NTase1 PF05636.11 OAG03826.1 - 0.01 15.1 0.4 0.013 14.7 0.4 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase RGS PF00615.19 OAG03827.1 - 0.0066 16.7 0.1 0.015 15.6 0.1 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain zf-C2H2 PF00096.26 OAG03831.1 - 1.1e-12 47.7 10.4 6.7e-07 29.4 0.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG03831.1 - 2.8e-10 40.1 6.6 6.8e-05 23.4 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG03831.1 - 5.4e-08 32.9 10.6 1.5e-05 25.1 3.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG03831.1 - 8.3e-08 32.3 1.0 0.00027 21.1 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG03831.1 - 7.9e-06 25.7 3.1 0.0024 17.8 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG03831.1 - 0.0011 18.7 1.8 0.092 12.5 0.2 2.3 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2HE PF16278.5 OAG03831.1 - 0.0012 19.3 3.4 0.65 10.5 0.9 2.3 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 OAG03831.1 - 0.0035 17.7 1.6 0.042 14.2 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OAG03831.1 - 0.028 14.3 0.7 0.028 14.3 0.7 2.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 OAG03831.1 - 0.059 13.1 0.3 0.059 13.1 0.3 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain C1_1 PF00130.22 OAG03831.1 - 0.063 13.2 2.8 2.4 8.1 0.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 OAG03831.1 - 0.1 12.9 1.2 0.57 10.5 1.2 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 OAG03831.1 - 0.13 11.9 1.8 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 OAG03831.1 - 0.35 11.0 4.1 1.2 9.3 3.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-LYAR PF08790.11 OAG03831.1 - 0.5 10.3 4.8 6.3 6.8 0.4 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 OAG03831.1 - 1.8 8.5 5.7 5.7 6.9 4.9 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain SAYSvFN PF10260.9 OAG03833.1 - 0.14 12.1 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) SnoaL_2 PF12680.7 OAG03834.1 - 0.00033 21.2 0.9 0.001 19.7 0.0 2.3 2 1 1 3 3 3 1 SnoaL-like domain SnoaL PF07366.12 OAG03834.1 - 0.0008 19.2 0.1 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase DLH PF01738.18 OAG03834.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1257 PF06868.11 OAG03834.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) HSP20 PF00011.21 OAG03837.1 - 1.7e-13 50.6 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG03837.1 - 0.00017 21.0 0.1 0.001 18.6 0.1 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA NYN PF01936.18 OAG03838.1 - 2.4e-30 105.9 0.0 3.9e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 OAG03838.1 - 5.7e-12 45.3 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain DUF3425 PF11905.8 OAG03839.1 - 4.3e-15 55.8 0.8 1.3e-14 54.2 0.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) CFEM PF05730.11 OAG03840.1 - 2e-06 27.8 5.1 2.8e-06 27.3 5.1 1.3 1 1 0 1 1 1 1 CFEM domain LacAB_rpiB PF02502.18 OAG03841.1 - 2.1e-46 157.4 0.5 2.4e-46 157.2 0.5 1.1 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 OAG03841.1 - 0.0022 18.0 0.4 0.052 13.6 0.0 2.2 1 1 1 2 2 2 1 Glycine-rich SFCGS DUF4514 PF14986.6 OAG03841.1 - 0.2 11.6 2.5 0.52 10.3 1.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4514) Fungal_trans PF04082.18 OAG03843.1 - 1e-31 110.0 0.0 3.5e-31 108.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03843.1 - 9.8e-08 32.0 8.7 1.7e-07 31.3 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 OAG03844.1 - 1.2e-22 80.3 0.2 1.6e-22 79.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 OAG03844.1 - 2.8e-05 24.0 0.0 6.9e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain p450 PF00067.22 OAG03845.1 - 1.1e-71 242.0 0.0 1.5e-71 241.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAG03846.1 - 9.1e-43 146.0 0.0 3.7e-42 144.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG03846.1 - 9.2e-28 97.4 0.0 1.6e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG03846.1 - 9.4e-06 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG03846.1 - 0.0057 16.6 0.1 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding DUF1776 PF08643.10 OAG03846.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 OAG03846.1 - 0.096 12.2 0.1 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Eno-Rase_NADH_b PF12242.8 OAG03846.1 - 0.14 11.9 0.5 4.8 7.0 0.1 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3425 PF11905.8 OAG03847.1 - 3.2e-18 65.9 0.0 5.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG03847.1 - 0.0035 17.4 7.3 0.0062 16.6 7.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG03847.1 - 0.0077 16.3 6.5 0.013 15.5 6.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Rad4 PF03835.15 OAG03848.1 - 2.4e-29 101.9 0.0 8.8e-29 100.1 0.0 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAG03848.1 - 3.5e-28 97.8 0.3 7.8e-28 96.7 0.3 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAG03848.1 - 3.5e-18 65.2 0.1 7.1e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OAG03848.1 - 4.3e-17 62.8 2.1 4.3e-17 62.8 2.1 3.1 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Peroxidase_2 PF01328.17 OAG03849.1 - 1e-18 68.6 0.0 1.3e-18 68.2 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Gtr1_RagA PF04670.12 OAG03851.1 - 3.9e-71 239.1 0.1 4.7e-71 238.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAG03851.1 - 0.00014 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OAG03851.1 - 0.00027 20.4 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG03851.1 - 0.0007 19.7 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OAG03851.1 - 0.017 15.3 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG03851.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sp38 PF07354.12 OAG03851.1 - 0.028 13.9 0.1 0.065 12.7 0.0 1.5 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) AAA_14 PF13173.6 OAG03851.1 - 0.034 14.2 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG03851.1 - 0.053 13.9 0.0 0.13 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Cyt-b5 PF00173.28 OAG03852.1 - 6.3e-11 42.3 0.0 9.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3043 PF11241.8 OAG03852.1 - 0.048 13.7 3.1 0.085 12.9 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) MarC PF01914.17 OAG03852.1 - 0.27 10.6 0.0 0.41 10.0 0.0 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein Ribosomal_S25 PF03297.15 OAG03853.1 - 5.5e-38 129.2 2.4 5.9e-38 129.1 2.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 OAG03853.1 - 0.0021 17.8 0.2 0.0028 17.4 0.2 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 OAG03853.1 - 0.003 17.4 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 MarR family EAP30 PF04157.16 OAG03853.1 - 0.018 14.3 0.1 0.021 14.1 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family Rrf2 PF02082.20 OAG03853.1 - 0.029 14.7 0.1 0.041 14.2 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 OAG03853.1 - 0.044 13.3 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GntR PF00392.21 OAG03853.1 - 0.057 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family YcgR PF07317.12 OAG03853.1 - 0.077 12.9 0.1 0.099 12.5 0.1 1.1 1 0 0 1 1 1 0 Flagellar regulator YcgR MFS_1 PF07690.16 OAG03858.1 - 7.2e-33 114.0 42.0 9.5e-32 110.3 42.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Orf78 PF06024.12 OAG03858.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) TFIIA PF03153.13 OAG03859.1 - 0.03 14.3 9.8 0.036 14.1 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 OAG03859.1 - 1.4 7.0 8.2 1.8 6.7 8.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.16 OAG03860.1 - 2e-16 59.9 22.3 2e-16 59.9 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG03860.1 - 2.9e-07 29.7 7.1 2.9e-07 29.7 7.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter zf-C2H2 PF00096.26 OAG03861.1 - 4e-08 33.3 13.1 0.00036 20.8 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG03861.1 - 7.2e-06 26.2 11.8 1.3e-05 25.4 0.9 3.5 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG03861.1 - 2.9e-05 24.5 5.2 0.0048 17.6 0.8 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger Zn_clus PF00172.18 OAG03861.1 - 0.00014 21.9 11.0 0.00014 21.9 11.0 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.6 OAG03861.1 - 0.0005 20.0 2.9 0.0033 17.4 0.4 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.11 OAG03861.1 - 0.00055 19.8 0.7 0.00055 19.8 0.7 2.5 2 1 0 2 2 2 1 Putative transposase DNA-binding domain zf-C2H2_jaz PF12171.8 OAG03861.1 - 0.00056 20.1 9.3 0.0011 19.2 0.5 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG03861.1 - 0.0028 18.0 0.3 0.0028 18.0 0.3 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Fungal_trans PF04082.18 OAG03862.1 - 3.1e-06 26.4 0.8 7.9e-06 25.1 0.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Death PF00531.22 OAG03862.1 - 0.067 13.4 1.7 2.9 8.1 0.0 3.6 4 0 0 4 4 4 0 Death domain Peptidase_S15 PF02129.18 OAG03863.1 - 6.5e-38 130.9 0.1 6.5e-36 124.3 0.1 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG03863.1 - 8.5e-32 110.9 0.0 1.2e-31 110.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 OAG03863.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PhyH PF05721.13 OAG03864.1 - 0.00016 22.0 0.2 0.00043 20.6 0.2 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG03864.1 - 0.0011 17.8 0.1 0.085 11.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 OAG03864.1 - 0.098 13.6 0.1 0.28 12.1 0.1 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cutinase PF01083.22 OAG03865.1 - 2.9e-45 154.4 0.3 3.4e-45 154.2 0.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG03865.1 - 0.0086 15.6 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 OAG03865.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Trehalase PF01204.18 OAG03866.1 - 9e-119 397.6 4.1 2.8e-118 396.0 4.1 1.7 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 OAG03866.1 - 0.00038 19.5 0.1 0.00066 18.7 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase TGT PF01702.18 OAG03868.1 - 1.5e-142 474.9 0.0 1.7e-142 474.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fungal_trans_2 PF11951.8 OAG03871.1 - 2.7e-22 79.1 0.4 7.4e-16 57.9 0.5 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03871.1 - 1.6e-07 31.4 11.5 2.5e-07 30.7 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP30_Sin3_bdg PF13867.6 OAG03873.1 - 0.0013 19.0 0.1 0.22 11.9 0.0 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 BRO1 PF03097.18 OAG03874.1 - 2.2e-132 441.6 3.9 2.2e-132 441.6 3.9 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAG03874.1 - 2.4e-82 276.6 11.4 3.8e-82 275.9 11.4 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DnaJ_C PF01556.18 OAG03874.1 - 1.2e-36 126.1 0.1 1.9e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG03874.1 - 1.6e-22 79.4 1.9 5e-22 77.8 1.9 1.9 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG03874.1 - 1.1e-07 32.1 22.5 2.6e-07 30.9 22.5 1.7 1 0 0 1 1 1 1 DnaJ central domain Gp58 PF07902.11 OAG03874.1 - 0.0087 14.4 5.9 0.015 13.6 5.9 1.3 1 0 0 1 1 1 1 gp58-like protein DUF416 PF04222.12 OAG03874.1 - 0.048 13.1 1.4 0.21 11.0 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF416) RHH_7 PF16777.5 OAG03874.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG GFA PF04828.14 OAG03875.1 - 3e-06 27.5 0.8 3e-06 27.5 0.8 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.13 OAG03875.1 - 0.02 14.6 2.8 0.28 11.0 1.1 2.3 2 0 0 2 2 2 0 CSL zinc finger zf-FCS PF06467.14 OAG03875.1 - 0.031 14.2 3.9 0.45 10.5 3.9 2.3 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF4187 PF13821.6 OAG03877.1 - 0.14 12.0 0.1 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Fungal_trans_2 PF11951.8 OAG03878.1 - 0.00014 20.8 0.1 0.00067 18.6 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAG03879.1 - 2.2e-66 224.5 0.0 2.6e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 OAG03880.1 - 1.7e-07 31.3 0.0 2.3e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG03880.1 - 8.9e-05 22.8 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAG03880.1 - 0.0031 16.7 0.0 0.0064 15.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein SusD-like_3 PF14322.6 OAG03880.1 - 0.052 13.9 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Epimerase PF01370.21 OAG03880.1 - 0.058 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SAP18 PF06487.12 OAG03880.1 - 0.096 12.9 0.0 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) Semialdhyde_dh PF01118.24 OAG03880.1 - 0.099 13.1 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Flavin_Reduct PF01613.18 OAG03881.1 - 2.5e-19 69.9 0.0 3.5e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF3409 PF11889.8 OAG03881.1 - 0.043 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) Abhydrolase_1 PF00561.20 OAG03882.1 - 3.9e-09 36.5 0.1 1.8e-08 34.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG03882.1 - 0.00031 20.1 0.0 0.0021 17.4 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG03882.1 - 0.0063 17.1 0.0 0.0078 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family 2_5_RNA_ligase2 PF13563.6 OAG03883.1 - 5.6e-32 110.8 0.6 7e-32 110.4 0.6 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 OAG03884.1 - 1.3e-97 325.7 0.0 1.7e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OAG03884.1 - 6.1e-45 152.9 0.3 9.8e-45 152.2 0.3 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OAG03884.1 - 2.7e-09 37.2 0.2 6.3e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAG03884.1 - 0.029 14.5 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase YlbD_coat PF14071.6 OAG03884.1 - 0.046 14.0 1.2 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 Putative coat protein Trep_Strep PF09605.10 OAG03884.1 - 0.049 13.6 0.9 0.084 12.9 0.9 1.3 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Ank_3 PF13606.6 OAG03885.1 - 1.7e-08 34.0 2.3 1.5 9.6 0.0 6.3 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OAG03885.1 - 1.8e-07 31.6 0.1 0.57 10.8 0.0 5.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG03885.1 - 1.2e-05 25.8 0.0 0.052 14.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OAG03885.1 - 0.0039 17.6 3.2 2.5 8.7 0.0 4.3 3 1 0 3 3 3 1 Ankyrin repeat HSP70 PF00012.20 OAG03886.1 - 1.2e-11 43.5 0.4 5.6e-10 38.0 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OAG03886.1 - 0.0062 15.4 0.1 0.036 12.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein PAN_1 PF00024.26 OAG03887.1 - 0.034 14.1 0.7 0.078 13.0 0.7 1.6 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.6 OAG03887.1 - 0.051 13.5 0.5 0.098 12.6 0.5 1.4 1 0 0 1 1 1 0 PAN domain CDP-OH_P_transf PF01066.21 OAG03888.1 - 4.5e-11 43.4 0.2 4.5e-11 43.4 0.2 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DEAD PF00270.29 OAG03889.1 - 2.9e-47 160.7 0.1 5.4e-47 159.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG03889.1 - 1.2e-28 99.6 1.0 7.3e-28 97.1 0.3 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAG03889.1 - 0.00037 19.4 0.9 0.00037 19.4 0.9 2.0 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MCPsignal PF00015.21 OAG03889.1 - 0.016 15.0 1.9 0.024 14.4 0.9 1.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Glyco_hydro_18 PF00704.28 OAG03890.1 - 1.1e-55 189.6 0.2 1.3e-55 189.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG03890.1 - 2.3e-07 31.1 11.8 2.3e-07 31.1 11.8 3.3 4 1 0 4 4 4 2 Chitin recognition protein PI_PP_I PF18363.1 OAG03890.1 - 0.21 11.8 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain DUF3445 PF11927.8 OAG03891.1 - 5.4e-32 111.2 0.0 8.3e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) p450 PF00067.22 OAG03892.1 - 5e-52 177.2 0.0 6.8e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 OAG03893.1 - 4.4e-14 52.0 0.4 6.2e-14 51.5 0.4 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG03893.1 - 0.0037 16.9 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG03893.1 - 0.048 13.4 0.1 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF861) CENP-C_C PF11699.8 OAG03893.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like Peptidase_C12 PF01088.21 OAG03894.1 - 5.2e-43 147.3 0.0 6.2e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Iso_dh PF00180.20 OAG03895.1 - 3.9e-122 407.7 0.0 4.4e-122 407.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1996 PF09362.10 OAG03897.1 - 8.9e-79 264.8 0.2 1.1e-78 264.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lys PF00062.20 OAG03897.1 - 0.047 13.9 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family KGG PF10685.9 OAG03898.1 - 1e-22 79.7 14.5 1e-10 41.5 0.7 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Gpr1_Fun34_YaaH PF01184.19 OAG03899.1 - 0.15 11.6 7.4 0.19 11.3 7.4 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family DUF202 PF02656.15 OAG03899.1 - 9.6 6.7 9.1 9.1 6.8 4.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF202) zf-C2H2_jaz PF12171.8 OAG03900.1 - 0.00031 20.9 0.0 0.00098 19.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG03900.1 - 0.0018 18.6 0.0 0.0062 16.9 0.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 OAG03900.1 - 0.03 14.5 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 OAG03900.1 - 0.031 15.1 0.1 0.031 15.1 0.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG03900.1 - 0.056 13.9 10.6 0.23 12.0 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type DHO_dh PF01180.21 OAG03901.1 - 3.5e-67 226.7 0.4 1.6e-55 188.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.15 OAG03901.1 - 0.13 11.6 1.3 0.24 10.8 0.3 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase PcrB PF01884.17 OAG03901.1 - 1.6 8.2 4.5 3 7.3 0.1 2.7 3 0 0 3 3 3 0 PcrB family Glyco_hydro_28 PF00295.17 OAG03902.1 - 1.8e-48 165.3 13.4 2.2e-48 165.0 13.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 U-box PF04564.15 OAG03903.1 - 7.8e-23 80.4 0.0 1.5e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 OAG03903.1 - 2e-10 39.9 3.8 2.1e-05 24.3 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG03903.1 - 2e-10 40.0 5.4 9.3e-07 28.4 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG03903.1 - 1.2e-08 34.5 1.9 1e-07 31.5 0.4 2.4 1 1 1 2 2 2 1 TPR repeat TPR_16 PF13432.6 OAG03903.1 - 1.7e-07 31.8 0.8 0.00015 22.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG03903.1 - 5.5e-06 26.8 3.4 0.00055 20.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG03903.1 - 6.4e-06 26.5 3.1 0.012 16.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG03903.1 - 2.8e-05 24.3 1.7 0.0055 16.9 0.1 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OAG03903.1 - 4e-05 23.7 4.8 0.2 12.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG03903.1 - 0.00016 21.4 3.2 0.0079 16.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG03903.1 - 0.00029 21.0 3.7 0.058 13.7 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG03903.1 - 0.00093 19.7 0.7 0.22 12.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 OAG03903.1 - 0.002 18.9 3.2 0.0045 17.7 3.2 1.6 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_21 PF09976.9 OAG03903.1 - 0.002 17.9 0.2 0.0064 16.2 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 OAG03903.1 - 0.026 14.7 2.4 0.15 12.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 OAG03903.1 - 0.044 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_10 PF13374.6 OAG03903.1 - 0.074 12.9 0.2 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Nse PF11789.8 OAG03903.1 - 0.18 11.7 0.0 0.64 9.9 0.0 1.9 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit TPR_20 PF14561.6 OAG03903.1 - 0.22 11.9 3.7 25 5.3 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3545 PF12065.8 OAG03903.1 - 0.43 10.6 6.4 0.13 12.3 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) zf-C2H2_4 PF13894.6 OAG03905.1 - 0.0006 20.4 5.6 0.036 14.9 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG03905.1 - 0.0008 19.7 7.7 0.28 11.7 0.6 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG03905.1 - 0.0014 18.9 0.2 0.0041 17.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 OAG03905.1 - 0.0028 17.8 0.3 0.004 17.3 0.3 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-met PF12874.7 OAG03905.1 - 0.0092 16.3 4.2 0.036 14.5 0.0 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type HlyIII PF03006.20 OAG03906.1 - 8.5e-40 136.8 13.1 8.5e-40 136.8 13.1 1.5 2 0 0 2 2 2 1 Haemolysin-III related C2 PF00168.30 OAG03907.1 - 1.9e-20 73.1 0.0 3.8e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 OAG03907.1 - 1.3e-18 67.1 0.0 1.9e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain AA_permease PF00324.21 OAG03909.1 - 2.8e-127 425.2 40.8 3.5e-127 424.9 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG03909.1 - 6.9e-32 110.8 45.7 7.3e-32 110.7 44.9 1.4 1 1 1 2 2 2 1 Amino acid permease p450 PF00067.22 OAG03912.1 - 2.2e-57 194.9 0.0 3.2e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.21 OAG03913.1 - 6.6e-06 25.7 0.0 1.8e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_61 PF03443.14 OAG03914.1 - 8.5e-63 212.0 0.3 1e-62 211.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.22 OAG03914.1 - 0.014 15.2 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain FAD_binding_3 PF01494.19 OAG03915.1 - 1e-16 61.1 0.0 1.8e-16 60.4 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG03915.1 - 5.7e-05 22.9 0.3 0.00011 21.9 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG03915.1 - 0.0024 18.0 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG03915.1 - 0.0078 15.5 0.1 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG03915.1 - 0.11 11.3 0.4 0.2 10.5 0.2 1.5 1 1 0 1 1 1 0 Tryptophan halogenase CRT10 PF08728.10 OAG03916.1 - 1.5 6.9 5.5 1.7 6.7 5.5 1.1 1 0 0 1 1 1 0 CRT10 DUF966 PF06136.13 OAG03916.1 - 9.9 5.8 24.3 15 5.2 24.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Med10 PF09748.9 OAG03917.1 - 0.041 13.8 7.0 0.079 12.9 2.1 3.3 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Tnp_22_trimer PF17489.2 OAG03917.1 - 0.1 12.6 0.4 0.1 12.6 0.4 3.7 5 0 0 5 5 5 0 L1 transposable element trimerization domain DASH_Dam1 PF08653.10 OAG03917.1 - 0.3 10.9 4.4 1.8 8.4 0.0 3.8 3 1 0 4 4 4 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 OAG03917.1 - 3.8 8.0 18.3 1.3 9.5 0.5 5.4 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 OAG03917.1 - 4.3 7.7 10.0 1.9 8.8 0.6 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Endonuclease_7 PF02945.15 OAG03918.1 - 0.046 13.6 0.1 0.49 10.3 0.0 2.5 2 0 0 2 2 2 0 Recombination endonuclease VII EcKinase PF02958.20 OAG03919.1 - 4.5e-16 59.0 0.0 9.3e-15 54.7 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OAG03919.1 - 2.1e-08 33.5 0.0 5e-08 32.2 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1679) APH PF01636.23 OAG03919.1 - 1.8e-07 31.3 0.3 2.8e-07 30.7 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family 7TM_GPCR_Srh PF10318.9 OAG03920.1 - 0.17 10.9 5.9 0.086 11.9 3.1 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF5596 PF18082.1 OAG03920.1 - 0.54 10.1 1.9 0.9 9.4 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5596) p450 PF00067.22 OAG03921.1 - 4.5e-29 101.5 0.0 6.8e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 OAG03923.1 - 5e-05 23.3 11.1 0.00017 21.6 11.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG03924.1 - 1.2e-34 119.5 0.1 1.6e-34 119.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG03924.1 - 3.4e-25 89.0 0.1 4.3e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG03924.1 - 3.7e-10 40.0 0.2 4.7e-10 39.7 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG03924.1 - 0.066 12.6 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 OAG03924.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 OAG03924.1 - 0.1 12.4 2.1 2.6 7.9 1.1 2.5 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.18 OAG03926.1 - 3.2e-24 85.4 0.0 2.3e-22 79.3 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG03926.1 - 7e-07 29.3 9.0 1.2e-06 28.5 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP12 PF07542.11 OAG03927.1 - 9.4e-43 145.4 0.4 1.7e-42 144.5 0.4 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Oxysterol_BP PF01237.18 OAG03928.1 - 2.2e-136 454.6 0.4 4.1e-135 450.4 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 OAG03928.1 - 2.5e-17 62.7 0.4 1.1e-10 41.5 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG03928.1 - 1.7e-12 47.7 0.0 5.3e-07 30.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 OAG03928.1 - 3.9e-12 46.6 0.6 7.7e-12 45.7 0.6 1.5 1 0 0 1 1 1 1 PH domain Ank PF00023.30 OAG03928.1 - 2.4e-11 43.5 0.1 0.00029 21.1 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OAG03928.1 - 3.9e-11 43.3 0.1 0.0004 20.9 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG03928.1 - 4.1e-11 42.1 0.2 0.00043 20.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 OAG03928.1 - 3.5e-07 30.4 0.9 8.5e-07 29.2 0.9 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OAG03928.1 - 0.00016 22.1 5.6 0.00023 21.5 3.4 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain DUF1996 PF09362.10 OAG03930.1 - 6e-47 160.6 0.1 7.3e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Rax2 PF12768.7 OAG03931.1 - 0.00081 18.9 0.5 0.0012 18.3 0.5 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.10 OAG03931.1 - 0.0014 18.0 0.2 0.0014 18.0 0.2 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG03931.1 - 0.0042 17.2 2.0 0.0042 17.2 2.0 2.3 3 0 0 3 3 3 1 Podoplanin BatD PF13584.6 OAG03931.1 - 0.025 13.4 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance Stevor PF17410.2 OAG03931.1 - 0.059 12.9 0.1 0.089 12.3 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4448 PF14610.6 OAG03931.1 - 0.065 13.0 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OAG03931.1 - 0.079 12.9 0.2 0.079 12.9 0.2 1.5 2 0 0 2 2 2 0 TMEM154 protein family Activin_recp PF01064.23 OAG03931.1 - 6.8 7.9 16.4 3.8e+02 2.3 16.4 2.8 1 1 0 1 1 1 0 Activin types I and II receptor domain Glyco_hydro_18 PF00704.28 OAG03933.1 - 9.6e-56 189.8 0.0 1.1e-55 189.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAG03934.1 - 0.0028 18.1 21.3 0.007 16.8 20.7 2.1 1 1 0 1 1 1 1 Chitin recognition protein Atrophin-1 PF03154.15 OAG03934.1 - 1.8 6.8 16.2 2.5 6.3 16.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF2834 PF11196.8 OAG03935.1 - 0.023 15.0 12.6 0.54 10.6 0.3 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2834) AT_hook PF02178.19 OAG03935.1 - 0.1 12.5 3.7 0.23 11.5 3.7 1.6 1 0 0 1 1 1 0 AT hook motif BCNT PF07572.12 OAG03936.1 - 1e-22 80.0 0.4 2.3e-22 78.8 0.4 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development Sugar_tr PF00083.24 OAG03937.1 - 9e-133 443.4 30.7 1.1e-132 443.2 30.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG03937.1 - 2.1e-22 79.6 56.4 2.7e-19 69.3 31.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 OAG03937.1 - 0.0081 16.4 1.1 0.0081 16.4 1.1 3.7 5 0 0 5 5 5 1 Protein of unknown function (DUF2530) UPF0715 PF17094.5 OAG03937.1 - 4 8.0 8.8 0.89 10.1 1.9 2.8 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0715) CpeS PF09367.10 OAG03938.1 - 0.092 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 CpeS-like protein zf-CCCH_4 PF18044.1 OAG03938.1 - 0.11 12.3 2.0 0.17 11.7 2.0 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger LEM PF03020.15 OAG03938.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 LEM domain NYD-SP28_assoc PF14775.6 OAG03938.1 - 0.33 11.1 2.2 0.61 10.2 2.2 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Hexapep PF00132.24 OAG03939.1 - 8.1e-06 25.4 1.3 0.077 12.7 0.4 3.1 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAG03939.1 - 4.9e-05 23.7 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 OAG03939.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 OAG03939.1 - 0.013 13.7 0.1 0.018 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 OAG03939.1 - 0.059 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Ig_mannosidase PF17753.1 OAG03940.1 - 0.2 11.4 1.0 0.39 10.5 0.1 1.9 2 0 0 2 2 2 0 Ig-fold domain alpha-hel2 PF14456.6 OAG03940.1 - 1.2 8.4 3.2 2 7.6 3.2 1.4 1 1 0 1 1 1 0 Alpha-helical domain 2 zf-H2C2_2 PF13465.6 OAG03941.1 - 2.4e-08 34.0 21.5 2.8e-05 24.3 3.4 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG03941.1 - 4.8e-05 23.6 14.0 0.0016 18.8 4.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAG03941.1 - 0.018 15.1 2.0 6.1 7.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG03941.1 - 0.049 14.5 11.6 0.07 14.0 3.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG03941.1 - 0.099 13.0 2.3 0.29 11.5 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 OAG03941.1 - 0.27 11.9 0.1 0.27 11.9 0.1 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain Zn-C2H2_12 PF18112.1 OAG03941.1 - 1.1 9.8 3.9 2.5 8.6 0.1 3.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Rad51 PF08423.11 OAG03946.1 - 2.4e-08 33.6 0.0 0.0005 19.4 0.0 2.2 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 OAG03946.1 - 2.5e-07 30.3 0.0 2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 OAG03946.1 - 1.7e-05 24.5 0.4 0.00085 19.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 OAG03946.1 - 3.2e-05 23.5 0.0 8.7e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein IstB_IS21 PF01695.17 OAG03946.1 - 0.0015 18.3 0.1 0.0027 17.5 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 OAG03946.1 - 0.0078 16.0 0.0 0.039 13.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 OAG03946.1 - 0.047 13.2 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 OAG03946.1 - 0.33 11.4 1.3 1.9 8.9 1.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MOSC PF03473.17 OAG03947.1 - 4.4e-21 75.3 0.0 7.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG03947.1 - 4.7e-12 45.8 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Involucrin_N PF10583.9 OAG03947.1 - 0.025 15.1 0.0 0.37 11.4 0.0 2.3 2 0 0 2 2 2 0 Involucrin of squamous epithelia N-terminus DUF4267 PF14087.6 OAG03948.1 - 6.9e-13 48.6 3.2 9e-13 48.3 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4345 PF14248.6 OAG03948.1 - 0.52 10.2 7.5 0.031 14.2 2.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) SET PF00856.28 OAG03949.1 - 5e-08 33.5 0.1 1.9e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 SET domain PHD PF00628.29 OAG03949.1 - 9.5e-05 22.2 9.4 0.00018 21.3 9.4 1.5 1 0 0 1 1 1 1 PHD-finger COesterase PF00135.28 OAG03950.1 - 1e-86 291.9 0.7 4.6e-86 289.7 0.7 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG03950.1 - 2.5e-12 47.1 0.3 9.6e-12 45.2 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG03950.1 - 0.00011 21.8 0.6 0.00018 21.0 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG03950.1 - 0.03 14.9 0.3 0.058 14.0 0.3 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lectin_C PF00059.21 OAG03950.1 - 0.044 14.5 0.4 1.7 9.4 0.1 2.4 1 1 1 2 2 2 0 Lectin C-type domain Hydrolase_4 PF12146.8 OAG03950.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_16 PF10294.9 OAG03951.1 - 1.9e-12 47.2 0.0 5.5e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase AMP-binding PF00501.28 OAG03952.1 - 1.1e-86 291.2 0.0 1.5e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG03952.1 - 0.00028 21.8 0.1 0.00083 20.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cu_bind_like PF02298.17 OAG03953.1 - 0.0046 16.9 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 OAG03953.1 - 0.06 13.8 0.2 0.15 12.5 0.2 1.7 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family PAS_3 PF08447.12 OAG03954.1 - 7e-12 45.5 0.0 6.9e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OAG03954.1 - 8.9e-08 32.3 0.0 0.00024 21.3 0.0 2.5 2 1 0 2 2 2 2 PAS domain PAS PF00989.25 OAG03954.1 - 4.1e-06 26.8 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 OAG03954.1 - 8.2e-05 22.7 0.0 0.00093 19.3 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OAG03954.1 - 0.00059 20.1 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold Apt1 PF10351.9 OAG03954.1 - 0.36 9.6 4.2 0.51 9.1 4.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPP1 PF05630.11 OAG03956.1 - 1e-56 192.2 0.1 1.2e-56 191.9 0.1 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Xan_ur_permease PF00860.20 OAG03957.1 - 1.3e-67 228.2 30.1 2.9e-66 223.8 30.1 2.0 1 1 0 1 1 1 1 Permease family FA_desaturase PF00487.24 OAG03958.1 - 7.3e-19 68.6 14.3 7.3e-19 68.6 14.3 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAG03958.1 - 1.3e-15 57.3 0.1 2.4e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tyr-DNA_phospho PF06087.12 OAG03959.1 - 1.2e-145 485.6 0.0 1.4e-145 485.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase C1ORF64 PF15547.6 OAG03959.1 - 0.0052 17.3 0.0 0.021 15.3 0.1 2.0 2 0 0 2 2 2 1 Steroid receptor-associated and regulated protein PLDc_2 PF13091.6 OAG03959.1 - 0.0069 16.3 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Pkinase PF00069.25 OAG03960.1 - 3.5e-71 239.7 0.0 4.5e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG03960.1 - 3.1e-43 147.9 0.0 4e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG03960.1 - 1.3e-08 34.5 0.0 9.6e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAG03960.1 - 0.0001 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAG03960.1 - 0.012 15.2 0.1 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAG03960.1 - 0.015 14.9 0.2 0.08 12.5 0.0 2.1 2 1 1 3 3 3 0 RIO1 family Haspin_kinase PF12330.8 OAG03960.1 - 0.025 13.5 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Synapsin PF02078.16 OAG03960.1 - 0.039 14.2 0.0 1.2 9.5 0.0 2.9 3 0 0 3 3 3 0 Synapsin, N-terminal domain APH PF01636.23 OAG03960.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OAG03960.1 - 0.1 12.1 0.2 0.3 10.6 0.2 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 OAG03960.1 - 0.19 10.4 0.9 0.29 9.8 0.9 1.4 1 1 0 1 1 1 0 Fungal protein kinase TIP41 PF04176.13 OAG03961.1 - 2.4e-71 238.7 0.0 2.9e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family ACBP PF00887.19 OAG03962.1 - 2.4e-18 66.1 0.8 2.7e-18 66.0 0.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_M76 PF09768.9 OAG03963.1 - 3.4e-66 222.2 3.1 4e-66 222.0 3.1 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 OAG03963.1 - 0.038 14.3 0.3 0.066 13.5 0.3 1.4 1 0 0 1 1 1 0 Effector protein SprT-like PF10263.9 OAG03963.1 - 0.048 13.5 2.3 0.061 13.2 1.6 1.8 1 1 1 2 2 2 0 SprT-like family AA_kinase PF00696.28 OAG03964.1 - 2.9e-40 138.4 0.6 4.3e-40 137.8 0.6 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 OAG03964.1 - 5.9e-16 58.2 1.2 1.7e-08 34.3 0.1 3.1 3 0 0 3 3 3 2 PUA domain ABC_tran PF00005.27 OAG03967.1 - 1.4e-27 96.9 0.1 2.7e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OAG03967.1 - 3.7e-15 55.9 9.7 3.7e-15 55.9 9.7 2.2 3 0 0 3 3 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OAG03967.1 - 7.4e-10 38.5 3.9 1.3e-09 37.7 3.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAG03967.1 - 3.5e-05 23.8 0.3 0.076 12.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAG03967.1 - 0.0039 17.6 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG03967.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OAG03967.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAG03967.1 - 0.026 14.9 0.4 0.09 13.2 0.4 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OAG03967.1 - 0.056 12.7 0.2 0.38 10.0 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 OAG03967.1 - 0.067 12.6 0.5 0.59 9.5 0.5 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAG03967.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 OAG03967.1 - 0.1 12.3 0.2 0.23 11.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG03967.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG03967.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAG03967.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG03967.1 - 0.18 12.2 0.2 1.2 9.6 0.0 2.3 3 0 0 3 3 2 0 RNA helicase AAA_23 PF13476.6 OAG03967.1 - 0.22 12.0 0.1 0.4 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG03967.1 - 1.8 8.5 3.9 1.3 8.9 0.4 2.4 2 1 1 3 3 3 0 NACHT domain p450 PF00067.22 OAG03968.1 - 1.1e-13 50.8 0.0 2.4e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Sterol_MT_C PF08498.10 OAG03970.1 - 4e-24 84.7 0.1 7.9e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 OAG03970.1 - 3.5e-18 66.0 0.1 6.5e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG03970.1 - 4.5e-17 62.2 0.0 6.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG03970.1 - 6e-17 62.1 0.1 1.2e-16 61.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG03970.1 - 2.6e-12 46.6 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG03970.1 - 1.2e-08 34.6 0.0 1.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG03970.1 - 2.3e-08 34.1 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG03970.1 - 1e-07 32.6 0.0 2.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG03970.1 - 0.00021 21.1 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OAG03970.1 - 0.0025 17.4 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 OAG03970.1 - 0.0047 16.3 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OAG03970.1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG03970.1 - 0.029 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 OAG03970.1 - 0.052 13.1 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 OAG03970.1 - 0.069 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 OAG03970.1 - 0.098 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.18 OAG03970.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 EAP30 PF04157.16 OAG03971.1 - 4.5e-43 147.2 0.7 5.9e-43 146.8 0.7 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 OAG03971.1 - 3.4e-23 80.8 1.3 3.4e-23 80.8 1.3 2.4 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 OAG03971.1 - 2.6e-22 78.8 0.0 4.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 OAG03971.1 - 5.6e-06 26.3 2.9 0.0038 17.2 0.1 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 OAG03971.1 - 0.00026 20.2 1.0 0.00026 20.2 1.0 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 OAG03971.1 - 0.045 13.8 0.5 0.045 13.8 0.5 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF3646 PF12362.8 OAG03971.1 - 0.11 12.8 0.3 0.32 11.3 0.3 1.8 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Ephrin_rec_like PF07699.13 OAG03971.1 - 5.1 6.9 7.4 0.16 11.7 1.2 1.7 2 0 0 2 2 2 0 Putative ephrin-receptor like SAC3_GANP PF03399.16 OAG03972.1 - 2.2e-25 89.7 0.6 1.8e-23 83.4 0.6 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAG03972.1 - 1.9e-05 24.7 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 OAG03973.1 - 3.8e-23 80.8 0.0 1.5e-11 43.7 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OAG03973.1 - 2.2e-16 59.4 0.1 2.6e-07 30.4 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 OAG03973.1 - 2.8e-11 42.9 0.0 4.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 OAG03973.1 - 4.4e-11 42.8 0.0 8.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 OAG03973.1 - 7.7e-05 22.6 0.2 0.00014 21.7 0.2 1.4 1 0 0 1 1 1 1 PB1 domain TIM21 PF08294.11 OAG03975.1 - 9.6e-34 116.3 0.0 1.1e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 OAG03975.1 - 8.5e-06 25.5 0.0 1.9e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 FTP PF07504.13 OAG03975.1 - 0.069 13.0 1.1 0.3 11.0 0.0 2.3 3 0 0 3 3 3 0 Fungalysin/Thermolysin Propeptide Motif AAA PF00004.29 OAG03976.1 - 2.6e-36 124.9 0.0 4.7e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG03976.1 - 1.6e-08 34.2 0.0 3.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OAG03976.1 - 1.4e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG03976.1 - 4.2e-05 24.0 1.0 0.00049 20.5 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 OAG03976.1 - 8.2e-05 22.6 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG03976.1 - 8.3e-05 22.6 0.1 0.00077 19.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG03976.1 - 0.00023 21.5 0.1 0.0061 16.8 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 OAG03976.1 - 0.00024 21.2 0.0 0.0005 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 OAG03976.1 - 0.00068 20.2 0.0 0.0029 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG03976.1 - 0.00075 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAG03976.1 - 0.00081 19.2 0.0 0.0022 17.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OAG03976.1 - 0.0012 18.3 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OAG03976.1 - 0.0012 18.4 0.1 0.034 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG03976.1 - 0.0017 18.7 0.0 0.0049 17.2 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 OAG03976.1 - 0.002 17.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 OAG03976.1 - 0.0031 17.0 0.0 2.8 7.3 0.0 2.4 1 1 0 2 2 2 2 Bacterial TniB protein AAA_28 PF13521.6 OAG03976.1 - 0.0047 17.2 0.2 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG03976.1 - 0.0048 16.8 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.6 OAG03976.1 - 0.013 15.6 0.0 0.038 14.1 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Rad17 PF03215.15 OAG03976.1 - 0.028 14.3 0.1 0.062 13.2 0.1 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 OAG03976.1 - 0.029 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 OAG03976.1 - 0.029 14.9 0.0 0.056 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 OAG03976.1 - 0.032 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 OAG03976.1 - 0.038 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAG03976.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OAG03976.1 - 0.096 12.6 0.0 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_21 PF13304.6 OAG03976.1 - 0.11 12.3 0.5 15 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system PGA2 PF07543.12 OAG03976.1 - 0.11 12.5 1.8 0.27 11.2 0.2 2.1 2 1 0 2 2 2 0 Protein trafficking PGA2 TsaE PF02367.17 OAG03976.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_kin PF00625.21 OAG03976.1 - 0.15 11.7 0.0 1 9.0 0.0 2.3 2 1 0 3 3 3 0 Guanylate kinase NB-ARC PF00931.22 OAG03976.1 - 0.22 10.7 0.1 0.6 9.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Coatomer_WDAD PF04053.14 OAG03977.1 - 1.6e-171 571.3 0.0 4e-171 570.0 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 OAG03977.1 - 9.1e-38 127.6 2.4 4.3e-06 27.4 0.0 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG03977.1 - 1.4e-05 25.3 0.1 22 5.4 0.0 5.9 4 2 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG03977.1 - 0.00029 19.6 1.9 0.15 10.7 0.0 3.7 2 2 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 OAG03977.1 - 0.0066 16.5 0.0 1.2 9.2 0.0 3.4 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 OAG03977.1 - 0.069 13.4 0.1 0.4 10.9 0.0 2.1 2 1 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase TPR_4 PF07721.14 OAG03977.1 - 2.9 8.8 4.2 30 5.6 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BTB PF00651.31 OAG03982.1 - 0.00075 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HypA PF01155.19 OAG03982.1 - 0.01 15.9 0.5 0.03 14.4 0.5 1.8 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 OAG03982.1 - 0.4 10.5 6.4 0.12 12.2 2.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Fer4_20 PF14691.6 OAG03982.1 - 1.3 8.8 6.1 3.2 7.5 4.1 2.4 1 1 1 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Peptidase_M28 PF04389.17 OAG03983.1 - 1.5e-31 109.7 0.0 6.4e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG03983.1 - 7.4e-09 35.6 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OAG03983.1 - 0.00026 20.1 0.1 0.062 12.3 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Nicastrin PF05450.15 OAG03983.1 - 0.047 13.2 0.1 0.88 9.0 0.0 2.2 2 0 0 2 2 2 0 Nicastrin R3H-assoc PF13902.6 OAG03984.1 - 4.7e-23 82.1 1.4 9.2e-23 81.1 1.4 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain ABC_tran PF00005.27 OAG03985.1 - 1.1e-45 155.5 0.0 4.6e-29 101.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG03985.1 - 1.1e-36 126.9 37.3 4.2e-24 85.7 9.5 4.0 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.19 OAG03985.1 - 2.7e-16 59.7 0.8 5.7e-07 29.2 0.0 5.2 5 1 0 6 6 6 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG03985.1 - 4.3e-08 33.3 0.1 0.032 14.0 0.0 4.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAG03985.1 - 1.4e-07 32.0 0.1 0.014 15.8 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG03985.1 - 2.1e-07 31.3 0.0 0.041 14.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG03985.1 - 2e-05 24.2 0.2 0.026 14.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 OAG03985.1 - 7.2e-05 22.4 0.2 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAG03985.1 - 0.00028 21.4 7.2 0.0053 17.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 OAG03985.1 - 0.00031 20.9 1.4 0.00056 20.1 0.1 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 OAG03985.1 - 0.0019 17.3 0.0 2 7.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 OAG03985.1 - 0.0027 17.1 0.1 0.041 13.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_13 PF13166.6 OAG03985.1 - 0.013 14.1 0.0 0.05 12.2 0.0 1.9 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OAG03985.1 - 0.024 14.7 0.0 5.4 7.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG03985.1 - 0.034 14.1 0.0 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC_ATPase PF09818.9 OAG03985.1 - 0.051 12.4 0.5 0.21 10.3 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 OAG03985.1 - 0.053 13.4 0.3 15 5.4 0.1 2.8 3 0 0 3 3 3 0 NACHT domain ATPase_2 PF01637.18 OAG03985.1 - 0.082 12.8 0.0 0.69 9.8 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OAG03985.1 - 0.12 12.5 0.0 19 5.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OAG03985.1 - 0.12 12.1 0.0 6 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 OAG03985.1 - 1.9 7.7 3.3 31 3.8 0.0 3.3 4 0 0 4 4 4 0 Zeta toxin adh_short PF00106.25 OAG03987.1 - 7.5e-35 120.2 0.0 8e-26 90.7 0.0 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG03987.1 - 2.5e-19 69.8 0.0 5.5e-14 52.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG03987.1 - 1.4e-09 38.2 0.0 1.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG03987.1 - 0.022 13.9 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG03987.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F-box-like PF12937.7 OAG03989.1 - 3.2e-06 26.9 0.1 8.2e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG03989.1 - 0.0023 17.8 0.8 0.005 16.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain DUF4079 PF13301.6 OAG03990.1 - 0.01 16.0 5.5 0.14 12.3 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 OAG03990.1 - 0.068 13.3 8.9 0.032 14.4 5.1 2.1 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF1129 PF06570.11 OAG03990.1 - 0.88 9.0 6.6 0.44 10.0 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Amidase PF01425.21 OAG03991.1 - 3.1e-57 194.5 0.0 7.7e-51 173.5 0.0 2.2 2 0 0 2 2 2 2 Amidase Fungal_trans PF04082.18 OAG03993.1 - 4.3e-69 232.5 0.4 6.1e-69 232.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG03993.1 - 0.00028 21.2 16.5 0.0012 19.1 2.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG03993.1 - 0.2 12.1 10.3 0.57 10.7 4.5 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Mob1_phocein PF03637.17 OAG03994.1 - 2.2e-25 89.6 0.2 3.3e-25 89.1 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.19 OAG03995.1 - 2e-47 161.0 0.1 2.8e-47 160.6 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAG03995.1 - 4.5e-08 32.9 0.0 8.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OAG03995.1 - 3.8e-06 26.9 0.3 0.049 13.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 OAG03995.1 - 0.0015 19.1 0.3 0.0015 19.1 0.3 1.6 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 OAG03995.1 - 0.0024 17.4 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OAG03995.1 - 0.0033 17.8 0.0 0.0082 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 OAG03995.1 - 0.0068 15.4 1.1 0.81 8.6 0.2 2.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 OAG03995.1 - 0.0083 15.9 0.2 0.16 11.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG03995.1 - 0.0089 16.1 0.0 0.02 15.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OAG03995.1 - 0.011 15.4 0.3 0.068 12.9 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG03995.1 - 0.012 15.8 0.3 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG03995.1 - 0.028 14.9 0.1 0.095 13.2 0.1 1.8 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 OAG03995.1 - 0.032 14.0 0.1 6.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 OAG03995.1 - 0.054 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1_Xtn PF16897.5 OAG03995.1 - 0.075 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Nucleoporin_N PF08801.11 OAG03996.1 - 2.2e-68 231.0 0.0 2.7e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OAG03996.1 - 1.5e-52 179.1 3.3 3.4e-52 178.0 1.6 1.9 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal YqeY PF09424.10 OAG03997.1 - 1.5e-22 80.2 4.4 1.9e-22 79.9 4.4 1.0 1 0 0 1 1 1 1 Yqey-like protein CBP4 PF07960.11 OAG03997.1 - 0.041 13.7 0.1 0.069 13.0 0.1 1.3 1 1 0 1 1 1 0 CBP4 BPL_N PF09825.9 OAG03997.1 - 0.043 12.9 0.1 0.049 12.7 0.1 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal GatB_Yqey PF02637.18 OAG03997.1 - 0.17 11.7 5.5 0.54 10.1 2.0 2.3 1 1 1 2 2 2 0 GatB domain Arv1 PF04161.13 OAG04000.1 - 8.9e-70 235.1 0.0 1e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 OAG04001.1 - 1.7e-21 76.5 1.7 1.8e-21 76.3 1.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF1129 PF06570.11 OAG04001.1 - 0.055 12.9 0.4 0.073 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 OAG04001.1 - 0.086 12.5 0.6 0.094 12.4 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Popeye PF04831.13 OAG04001.1 - 0.12 12.5 1.1 0.14 12.3 1.1 1.1 1 0 0 1 1 1 0 Popeye protein conserved region CoA_binding_2 PF13380.6 OAG04003.1 - 3.6e-28 98.4 0.0 4.4e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain adh_short PF00106.25 OAG04004.1 - 1.5e-22 80.0 0.2 2.1e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04004.1 - 1.2e-18 67.5 0.4 1.5e-18 67.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04004.1 - 6.1e-11 42.6 0.2 7.3e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG04004.1 - 0.0011 19.0 0.0 0.0014 18.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding WD-3 PF09765.9 OAG04004.1 - 0.032 13.6 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 WD-repeat region Kinesin_assoc PF16183.5 OAG04004.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.3 1 1 0 1 1 1 0 Kinesin-associated Haem_degrading PF03928.14 OAG04005.1 - 2.4e-25 88.9 0.0 3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading HEAT PF02985.22 OAG04007.1 - 8e-16 56.8 11.5 0.00014 21.9 0.0 9.8 11 1 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 OAG04007.1 - 3e-14 53.2 8.4 3.4e-09 37.0 0.0 7.5 5 2 2 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 OAG04007.1 - 1.8e-11 44.3 8.4 0.0045 17.4 0.0 7.3 3 2 5 8 8 8 5 HEAT repeats IBN_N PF03810.19 OAG04007.1 - 4e-09 36.3 6.6 1.5e-07 31.2 1.9 4.3 3 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 OAG04007.1 - 9.8e-09 35.1 0.1 0.0095 15.5 0.0 4.3 3 1 0 4 4 4 3 CLASP N terminal Ecm29 PF13001.7 OAG04007.1 - 1.7e-06 27.1 3.0 0.036 12.7 0.0 4.2 2 2 2 4 4 4 3 Proteasome stabiliser Arm PF00514.23 OAG04007.1 - 9.1e-06 25.5 4.0 1.5 9.0 0.0 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 OAG04007.1 - 2.8e-05 24.4 0.5 37 5.4 0.0 6.4 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat Xpo1 PF08389.12 OAG04007.1 - 0.0015 18.6 13.8 0.58 10.2 0.0 6.1 4 3 2 6 6 6 2 Exportin 1-like protein DUF3385 PF11865.8 OAG04007.1 - 0.0051 16.7 3.1 3.8 7.4 0.8 4.6 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) DUF3338 PF11819.8 OAG04007.1 - 0.16 12.0 2.2 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) PP2C PF00481.21 OAG04008.1 - 4.9e-36 124.7 0.0 4.1e-30 105.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OAG04008.1 - 0.00065 19.4 0.0 0.0018 18.0 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C Nucleoplasmin PF03066.15 OAG04009.1 - 0.05 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain GPI-anchored PF10342.9 OAG04010.1 - 0.16 12.8 0.0 5.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_2 PF02368.18 OAG04010.1 - 1.4 8.9 6.8 3.3 7.7 6.8 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) MIF PF01187.18 OAG04011.1 - 1.2e-13 51.3 0.0 2.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) CENP-X PF09415.10 OAG04013.1 - 1.6e-22 79.6 0.0 2.4e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Cu_bind_like PF02298.17 OAG04014.1 - 0.018 15.1 0.5 0.067 13.2 0.5 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.20 OAG04014.1 - 0.029 14.8 0.2 0.058 13.8 0.2 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Thaumatin PF00314.17 OAG04015.1 - 1.3e-68 230.9 3.4 1.7e-68 230.5 3.4 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 OAG04015.1 - 0.0069 15.7 0.1 0.23 10.7 0.0 2.1 2 0 0 2 2 2 2 Beta-1,3-glucanase Mannosidase_ig PF17786.1 OAG04016.1 - 2.8e-19 69.5 0.3 9.6e-19 67.8 0.3 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAG04016.1 - 2.2e-10 41.2 0.2 1.2e-09 38.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 OAG04016.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Fungal_trans PF04082.18 OAG04017.1 - 5.5e-22 78.1 0.2 9e-22 77.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG04017.1 - 1.1e-07 31.8 8.5 2e-07 31.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.28 OAG04020.1 - 5.7e-19 68.0 1.0 1.1e-18 67.2 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 OAG04020.1 - 8.5e-13 48.8 20.9 8.5e-13 48.8 20.9 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 OAG04020.1 - 0.022 14.6 0.1 0.052 13.4 0.1 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.13 OAG04020.1 - 0.041 14.1 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.22 OAG04021.1 - 5.4e-47 157.5 2.5 4.7e-21 74.4 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OAG04021.1 - 5.8e-09 36.9 0.5 2.4e-08 35.0 0.5 2.0 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 OAG04021.1 - 1.3e-07 31.3 0.0 0.007 16.2 0.0 3.5 3 1 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG04021.1 - 0.00027 20.9 0.0 0.59 10.2 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG04021.1 - 0.0069 16.4 0.5 0.81 9.8 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif RRM_5 PF13893.6 OAG04021.1 - 0.044 13.4 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAG04021.1 - 0.049 13.9 0.4 2.4 8.4 0.1 3.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Dynein_light PF01221.18 OAG04021.1 - 0.15 12.4 0.2 0.32 11.3 0.2 1.5 1 0 0 1 1 1 0 Dynein light chain type 1 RRM_7 PF16367.5 OAG04021.1 - 0.16 12.1 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif DUF2759 PF10958.8 OAG04022.1 - 0.79 9.5 5.5 1.2 8.9 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) Alpha-amylase PF00128.24 OAG04023.1 - 6.5e-17 62.1 1.6 1.9e-16 60.6 1.6 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 OAG04023.1 - 4.2e-14 52.8 0.1 7.5e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 OAG04023.1 - 3.9e-06 27.3 0.0 7.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OAG04023.1 - 8.7e-06 25.4 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4481 PF14800.6 OAG04023.1 - 1.3 8.4 2.6 2.2 7.7 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) adh_short PF00106.25 OAG04025.1 - 2.4e-14 53.3 0.0 2.8e-13 49.8 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04025.1 - 3.9e-13 49.5 0.0 5.3e-11 42.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Queuosine_synth PF02547.15 OAG04025.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein Amidase PF01425.21 OAG04027.1 - 1.4e-76 258.3 0.3 5.2e-71 239.9 0.0 2.2 2 0 0 2 2 2 2 Amidase Zip PF02535.22 OAG04028.1 - 0.045 13.0 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ERO1 PF04137.15 OAG04028.1 - 0.064 12.4 0.2 0.069 12.3 0.2 1.0 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF4746 PF15928.5 OAG04028.1 - 0.18 11.2 4.4 0.2 11.1 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NARP1 PF12569.8 OAG04028.1 - 0.23 10.3 3.4 0.25 10.2 3.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SDA1 PF05285.12 OAG04028.1 - 0.29 10.5 9.5 0.33 10.3 9.5 1.0 1 0 0 1 1 1 0 SDA1 Roughex PF06020.11 OAG04028.1 - 2.2 7.3 5.9 2.4 7.1 5.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein NOA36 PF06524.12 OAG04028.1 - 7.4 5.8 10.3 9.2 5.5 10.3 1.1 1 0 0 1 1 1 0 NOA36 protein SKG6 PF08693.10 OAG04029.1 - 0.12 11.8 0.7 0.38 10.2 0.7 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ACPS PF01648.20 OAG04030.1 - 3.2e-08 33.7 0.0 4e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 OAG04030.1 - 0.00095 19.2 0.4 1.9 8.7 0.1 2.3 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain Retrotran_gag_2 PF14223.6 OAG04031.1 - 7.8e-05 22.4 0.3 0.00038 20.1 0.2 2.2 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 OAG04031.1 - 0.00052 19.8 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CAML PF14963.6 OAG04031.1 - 1.3 9.1 3.6 2.2 8.4 3.6 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Aminotran_1_2 PF00155.21 OAG04032.1 - 5.8e-78 262.6 0.0 1e-77 261.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 OAG04033.1 - 2.9e-10 40.2 2.0 1.3e-09 38.1 0.1 3.1 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 OAG04033.1 - 0.0029 17.6 1.9 0.0044 17.0 0.0 2.3 3 0 0 3 3 3 1 SNARE domain DprA_WH PF17782.1 OAG04033.1 - 0.014 15.5 2.0 0.045 13.9 0.1 2.5 2 0 0 2 2 2 0 DprA winged helix domain TubC_N PF18563.1 OAG04033.1 - 0.032 14.2 0.1 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 TubC N-terminal docking domain Polysacc_deac_1 PF01522.21 OAG04033.1 - 0.14 12.1 1.5 0.46 10.4 0.2 2.7 2 1 0 2 2 2 0 Polysaccharide deacetylase DUF334 PF03904.13 OAG04033.1 - 0.56 9.7 6.5 0.11 12.0 1.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF334) PDE4_UCR PF18100.1 OAG04033.1 - 1.1 10.0 5.6 1.1 9.9 0.2 2.7 2 1 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) KELK PF15796.5 OAG04033.1 - 1.1 9.7 11.0 4.2 7.9 1.7 3.5 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Laminin_II PF06009.12 OAG04033.1 - 3.9 7.5 12.6 6.7 6.7 3.1 2.9 3 0 0 3 3 3 0 Laminin Domain II MFS_1 PF07690.16 OAG04034.1 - 3.5e-45 154.5 19.6 3.5e-45 154.5 19.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04034.1 - 2.4e-07 30.0 6.7 2.4e-07 30.0 6.7 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Osw5 PF17062.5 OAG04034.1 - 0.025 14.7 0.4 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 Outer spore wall 5 RAP1 PF07218.11 OAG04036.1 - 0.11 10.7 4.9 0.15 10.3 4.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Atrophin-1 PF03154.15 OAG04037.1 - 0.076 11.3 16.3 0.085 11.1 16.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family Casc1_N PF15927.5 OAG04037.1 - 1.4 8.6 13.1 1.8 8.2 13.1 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Borrelia_P83 PF05262.11 OAG04037.1 - 2.3 6.6 13.7 2.3 6.6 13.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DBINO PF13892.6 OAG04037.1 - 3.5 8.0 18.7 4.9 7.5 18.2 1.6 1 1 0 1 1 1 0 DNA-binding domain Atg14 PF10186.9 OAG04037.1 - 4.3 6.3 9.1 4.4 6.3 9.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4872 PF16169.5 OAG04038.1 - 0.086 12.6 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) DUF3433 PF11915.8 OAG04039.1 - 3e-17 62.9 3.8 3e-17 62.9 3.8 3.8 5 0 0 5 5 5 1 Protein of unknown function (DUF3433) Herpes_gE PF02480.16 OAG04041.1 - 0.00046 19.1 0.0 0.00068 18.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E WBP-1 PF11669.8 OAG04041.1 - 0.0036 17.9 0.5 0.0036 17.9 0.5 2.0 2 0 0 2 2 2 1 WW domain-binding protein 1 TMEM154 PF15102.6 OAG04041.1 - 0.0039 17.1 0.0 0.0093 15.9 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 OAG04041.1 - 0.0039 17.0 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF5385 PF17359.2 OAG04041.1 - 0.019 14.6 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 OAG04041.1 - 0.022 15.6 0.1 0.051 14.5 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 OAG04041.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 SKG6 PF08693.10 OAG04041.1 - 0.042 13.3 6.8 0.082 12.3 6.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SARAF PF06682.12 OAG04041.1 - 0.36 10.4 5.6 1.2 8.7 0.1 2.4 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis PHD PF00628.29 OAG04042.1 - 1.6e-09 37.5 4.4 2.7e-09 36.8 4.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAG04042.1 - 0.024 14.2 2.4 0.043 13.4 2.4 1.4 1 0 0 1 1 1 0 PHD-finger AIM3 PF17096.5 OAG04043.1 - 0.00028 21.8 0.1 0.00028 21.8 0.1 5.6 5 1 0 5 5 5 1 Altered inheritance of mitochondria protein 3 DUF4650 PF15509.6 OAG04043.1 - 0.51 9.6 7.1 5.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4650) ELO PF01151.18 OAG04044.1 - 3.4e-82 275.7 8.1 4.5e-82 275.3 8.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ANAPC10 PF03256.16 OAG04045.1 - 1.7e-41 141.9 0.0 1.8e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Tim17 PF02466.19 OAG04046.1 - 0.0093 16.3 0.5 0.012 16.0 0.5 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2721 PF11026.8 OAG04047.1 - 1.2 9.0 3.7 3.2 7.7 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1996 PF09362.10 OAG04048.1 - 2.3e-83 279.8 3.2 2.9e-83 279.4 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FA_desaturase PF00487.24 OAG04049.1 - 6.8e-27 94.9 22.3 1.1e-26 94.2 22.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OAG04049.1 - 1.3e-05 25.5 0.1 2.7e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) His_Phos_2 PF00328.22 OAG04050.1 - 4.3e-62 210.6 0.0 5.1e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AA_permease_2 PF13520.6 OAG04051.1 - 1.1e-56 192.5 51.9 1.4e-56 192.2 51.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG04051.1 - 4.8e-13 48.5 49.4 9.7e-13 47.5 49.4 1.4 1 1 0 1 1 1 1 Amino acid permease Tyrosinase PF00264.20 OAG04053.1 - 1.4e-38 133.4 0.5 4.6e-38 131.7 0.5 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase KRAB PF01352.27 OAG04053.1 - 0.038 13.6 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 KRAB box Wzy_C PF04932.15 OAG04054.1 - 0.19 11.4 3.2 0.32 10.6 3.2 1.4 1 0 0 1 1 1 0 O-Antigen ligase RTA1 PF04479.13 OAG04056.1 - 5.9e-62 208.9 15.0 8.3e-62 208.5 15.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Cyclin_C PF02984.19 OAG04056.1 - 0.19 11.8 0.3 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain Hemerythrin PF01814.23 OAG04057.1 - 1.5e-08 35.3 1.5 2.2e-08 34.8 1.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain RNA_pol_I_TF PF04090.12 OAG04058.1 - 3.9e-08 33.0 0.0 1.9e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.6 OAG04058.1 - 0.037 14.7 2.2 1.9 9.3 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Host_attach PF10116.9 OAG04058.1 - 0.065 13.8 0.7 0.1 13.2 0.7 1.2 1 0 0 1 1 1 0 Protein required for attachment to host cells zf-RING_2 PF13639.6 OAG04059.1 - 7.9e-11 42.1 7.4 1.2e-10 41.6 7.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG04059.1 - 5.3e-07 29.8 5.2 9e-07 29.1 5.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAG04059.1 - 1.5e-06 27.8 5.7 2.6e-06 27.0 5.7 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG04059.1 - 3.7e-06 26.7 6.6 5.8e-06 26.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG04059.1 - 5.1e-06 26.3 6.0 7.8e-06 25.8 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG04059.1 - 7.9e-06 25.7 6.5 1.2e-05 25.1 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG04059.1 - 1.6e-05 24.8 3.6 3.1e-05 23.9 3.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OAG04059.1 - 0.0026 17.6 6.1 0.0044 16.9 6.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OAG04059.1 - 0.0046 17.0 2.3 0.0082 16.2 2.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OAG04059.1 - 0.011 15.5 5.1 0.019 14.8 5.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG04059.1 - 0.034 13.8 5.2 0.056 13.1 5.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OAG04059.1 - 0.4 10.8 1.3 0.84 9.7 1.3 1.5 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 OAG04059.1 - 1.5 9.0 5.8 5.2 7.3 5.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 OAG04059.1 - 4.4 7.3 5.9 0.66 9.9 1.4 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OAG04059.1 - 8.9 6.2 6.3 15 5.5 6.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Fungal_trans_2 PF11951.8 OAG04061.1 - 1.1e-09 37.6 1.1 1.5e-09 37.1 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG04061.1 - 9.2e-08 32.1 9.9 1.5e-07 31.4 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP1_TM PF14812.6 OAG04061.1 - 1 9.8 6.1 3.7 8.0 5.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BAR_2 PF10455.9 OAG04062.1 - 2.4e-63 214.0 0.2 3.5e-63 213.4 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 OAG04062.1 - 2.8e-18 66.4 3.5 3.1e-17 63.0 3.5 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 OAG04062.1 - 0.0058 16.4 0.8 0.081 12.6 0.2 2.4 2 1 0 2 2 2 1 BAR domain of APPL family GGACT PF06094.12 OAG04063.1 - 3.8e-06 27.5 0.0 5.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 OAG04063.1 - 2.4e-05 24.6 0.0 0.00017 21.9 0.0 2.3 2 1 0 2 2 2 1 AIG2-like family PHP PF02811.19 OAG04064.1 - 2.1e-13 50.9 0.8 3.8e-13 50.1 0.8 1.4 1 1 0 1 1 1 1 PHP domain FKBP_C PF00254.28 OAG04065.1 - 1.6e-23 82.8 0.0 2e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AstE_AspA PF04952.14 OAG04068.1 - 1.2e-30 106.6 0.0 1.4e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family RnfC_N PF13375.6 OAG04068.1 - 0.17 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Choline_kinase PF01633.20 OAG04072.1 - 3.7e-60 203.2 0.0 8.1e-60 202.0 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Mem_trans PF03547.18 OAG04072.1 - 9.6e-47 159.2 1.9 1.6e-46 158.4 1.9 1.3 1 0 0 1 1 1 1 Membrane transport protein Choline_kin_N PF04428.14 OAG04072.1 - 4.8e-18 64.6 0.0 1.4e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 OAG04072.1 - 6.8e-09 36.0 0.1 1.4e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3655 PF12379.8 OAG04072.1 - 6.5 7.1 6.4 16 5.9 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3655) Pkinase PF00069.25 OAG04073.1 - 4.4e-52 177.0 0.0 3e-49 167.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04073.1 - 3.4e-30 105.2 0.0 6.2e-29 101.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG04073.1 - 0.0033 16.8 0.0 0.0048 16.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OAG04073.1 - 0.0042 16.2 0.1 0.0065 15.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OAG04073.1 - 0.046 12.7 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG04073.1 - 0.047 12.5 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DnaJ PF00226.31 OAG04074.1 - 1.1e-15 57.5 0.4 2.9e-15 56.1 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 OAG04074.1 - 1.6e-15 57.0 0.0 1.5e-14 53.8 0.0 2.3 2 1 0 2 2 2 1 Sec63 Brl domain RRN3 PF05327.11 OAG04074.1 - 0.37 9.3 1.2 0.54 8.7 1.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UPF0167 PF03691.14 OAG04075.1 - 0.28 11.0 3.4 0.11 12.3 0.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) Presenilin PF01080.17 OAG04075.1 - 5.8 5.6 9.1 10 4.8 9.1 1.4 1 0 0 1 1 1 0 Presenilin VWA PF00092.28 OAG04077.1 - 8e-08 32.7 0.0 4.4e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG04077.1 - 0.00026 21.6 0.0 0.00057 20.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain AA_permease_2 PF13520.6 OAG04078.1 - 2.2e-72 244.2 42.6 2.7e-72 244.0 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG04078.1 - 5.8e-16 58.1 35.1 8.7e-16 57.6 35.1 1.2 1 0 0 1 1 1 1 Amino acid permease BCLP PF12304.8 OAG04078.1 - 5.7 6.4 10.0 0.38 10.3 2.3 2.7 3 0 0 3 3 3 0 Beta-casein like protein CASP_C PF08172.12 OAG04080.1 - 1.2e-90 303.3 0.4 1.2e-90 303.3 0.4 3.7 3 0 0 3 3 3 2 CASP C terminal PRKG1_interact PF15898.5 OAG04080.1 - 0.15 13.0 43.4 6.8 7.6 4.6 5.7 5 0 0 5 5 5 0 cGMP-dependent protein kinase interacting domain Shugoshin_N PF07558.11 OAG04080.1 - 0.18 11.7 10.3 0.21 11.5 0.8 4.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Spc24 PF08286.11 OAG04080.1 - 0.2 11.9 43.8 0.56 10.5 3.0 6.4 4 1 1 5 5 5 0 Spc24 subunit of Ndc80 ZapB PF06005.12 OAG04080.1 - 0.2 12.1 0.0 0.2 12.1 0.0 6.7 5 3 0 5 5 5 0 Cell division protein ZapB Fez1 PF06818.15 OAG04080.1 - 1.4 9.4 52.7 4.9 7.5 5.9 4.5 4 1 1 5 5 5 0 Fez1 FlaC_arch PF05377.11 OAG04080.1 - 1.7 9.1 38.8 1.9 9.0 0.1 6.6 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 OAG04080.1 - 3.7 6.8 43.2 3.2 7.0 10.1 5.1 2 1 1 4 4 4 0 Domain of unknown function (DUF4407) ADIP PF11559.8 OAG04080.1 - 3.9 7.6 66.0 0.092 12.8 2.4 6.9 5 2 1 7 7 7 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 OAG04080.1 - 4.8 7.7 70.8 3.6 8.1 10.7 5.7 3 2 2 5 5 5 0 Apg6 coiled-coil region Fib_alpha PF08702.10 OAG04080.1 - 6.2 7.0 25.8 0.51 10.5 6.2 4.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 OAG04080.1 - 8.3 6.5 68.9 1.2 9.2 7.8 7.0 6 1 1 7 7 7 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 OAG04080.1 - 9.6 6.3 30.5 2.9 8.0 0.9 6.4 5 1 2 7 7 7 0 Protein of unknown function (DUF1664) Vps39_2 PF10367.9 OAG04081.1 - 4.8e-06 27.0 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Prefoldin_2 PF01920.20 OAG04082.1 - 6.8e-24 83.9 2.0 8.2e-24 83.6 2.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit PI3K_P85_iSH2 PF16454.5 OAG04082.1 - 0.0025 17.4 5.6 0.026 14.1 5.6 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CpxA_peri PF16527.5 OAG04082.1 - 0.022 15.2 0.1 0.028 14.8 0.1 1.2 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain DUF1664 PF07889.12 OAG04082.1 - 0.057 13.5 1.6 2.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PKS_DE PF18369.1 OAG04082.1 - 0.16 12.6 2.0 19 5.9 0.1 2.5 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain bZIP_1 PF00170.21 OAG04082.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor NPV_P10 PF05531.12 OAG04082.1 - 0.29 11.6 1.8 3.4 8.2 0.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 OAG04082.1 - 0.89 9.8 9.9 14 6.0 6.0 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 OAG04082.1 - 5.2 7.6 7.7 7.1 7.1 0.2 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) MFS_1 PF07690.16 OAG04083.1 - 4.5e-40 137.6 42.3 4.5e-40 137.6 42.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04083.1 - 3.5e-10 39.3 10.7 3.5e-10 39.3 10.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter APH PF01636.23 OAG04084.1 - 0.00031 20.7 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG04084.1 - 0.012 14.5 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) FAD_binding_3 PF01494.19 OAG04085.1 - 4.6e-12 45.8 3.1 0.00087 18.6 0.3 3.2 2 1 1 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 OAG04085.1 - 0.0017 18.6 0.2 0.0043 17.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG04085.1 - 0.013 14.8 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG04085.1 - 0.066 12.2 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein SE PF08491.10 OAG04085.1 - 0.17 10.9 0.0 0.47 9.5 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase SdiA-regulated PF06977.11 OAG04086.1 - 0.22 10.7 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 SdiA-regulated Mis12 PF05859.12 OAG04087.1 - 2.3e-39 134.6 0.0 4e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein Pkinase PF00069.25 OAG04088.1 - 1.7e-51 175.2 0.0 3.6e-50 170.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04088.1 - 2.6e-20 72.8 0.0 2.6e-19 69.5 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAG04088.1 - 0.053 12.9 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4148 PF13663.6 OAG04088.1 - 0.074 13.2 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) AC_N PF16214.5 OAG04088.1 - 0.16 11.1 0.9 0.29 10.2 0.9 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Aminotran_3 PF00202.21 OAG04089.1 - 2.5e-68 230.6 0.0 3.2e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SRP19 PF01922.17 OAG04090.1 - 5.1e-35 120.3 0.0 7.3e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein HET PF06985.11 OAG04091.1 - 4.4e-32 111.4 0.0 8e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) His_Phos_1 PF00300.22 OAG04092.1 - 5.4e-15 55.6 4.3 1.1e-13 51.4 4.3 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Asp PF00026.23 OAG04093.1 - 1.8e-68 231.3 13.8 2.2e-68 231.0 13.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG04093.1 - 9.2e-06 26.0 6.9 0.037 14.3 1.8 3.1 1 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG04093.1 - 2.3e-05 25.0 2.4 0.0085 16.7 0.3 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG04093.1 - 0.078 13.5 0.3 1.5 9.5 0.1 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DEAD PF00270.29 OAG04094.1 - 6.3e-31 107.5 0.0 8.4e-28 97.3 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG04094.1 - 1.6e-22 79.9 0.0 6.2e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG04094.1 - 4.1e-06 26.9 0.3 1.6e-05 25.0 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OAG04094.1 - 4.1e-05 22.6 0.0 0.065 12.0 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 TRAP_alpha PF03896.16 OAG04094.1 - 0.039 13.2 0.5 0.076 12.2 0.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 OAG04094.1 - 0.42 8.6 7.7 0.65 8.0 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Smg8_Smg9 PF10220.9 OAG04094.1 - 4.9 5.3 10.7 0.026 12.9 2.0 1.5 2 0 0 2 2 2 0 Smg8_Smg9 YL1 PF05764.13 OAG04094.1 - 6 6.9 15.6 0.25 11.4 1.2 2.4 2 0 0 2 2 2 0 YL1 nuclear protein PIGA PF08288.12 OAG04095.1 - 2.1e-45 153.2 1.7 2.6e-45 152.9 0.5 1.8 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAG04095.1 - 3.3e-27 95.6 0.2 6.5e-27 94.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAG04095.1 - 1.3e-25 89.9 0.0 3.1e-25 88.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG04095.1 - 8.6e-25 87.7 0.5 2.4e-24 86.3 0.5 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG04095.1 - 3.2e-11 43.9 0.0 1.2e-10 42.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 OAG04095.1 - 0.00013 22.0 0.1 0.00067 19.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 OAG04095.1 - 0.00018 21.8 0.0 0.00051 20.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAG04095.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF3455 PF11937.8 OAG04096.1 - 8.8e-40 136.7 1.9 1.1e-39 136.3 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 OAG04096.1 - 0.32 11.2 0.1 0.32 11.2 0.1 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2990) MFS_1 PF07690.16 OAG04097.1 - 0.79 8.6 8.7 7.1 5.4 8.9 1.9 1 1 1 2 2 2 0 Major Facilitator Superfamily Isochorismatase PF00857.20 OAG04098.1 - 5.8e-18 65.7 0.1 6.4e-18 65.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Mob_synth_C PF06463.13 OAG04099.1 - 1.5e-35 121.9 0.0 3.4e-34 117.5 0.0 2.3 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OAG04099.1 - 6.3e-28 98.2 0.0 1.2e-27 97.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAG04099.1 - 0.00018 21.8 0.0 0.00052 20.3 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain MoaC PF01967.21 OAG04100.1 - 4.2e-49 166.1 1.2 5.1e-49 165.8 1.2 1.1 1 0 0 1 1 1 1 MoaC family PAP2 PF01569.21 OAG04101.1 - 6.6e-27 93.9 0.9 6.6e-27 93.9 0.9 2.1 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 OAG04101.1 - 0.0065 16.2 3.8 0.0065 16.2 3.8 3.2 2 1 1 3 3 3 2 PAP2 superfamily PAP2_C PF14360.6 OAG04101.1 - 5.8 7.5 7.1 1.2 9.7 0.7 2.8 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Metallophos PF00149.28 OAG04102.1 - 1.3e-12 48.7 0.2 2.3e-12 47.9 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG04102.1 - 1.6e-05 25.2 0.0 8.7e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1065 PF06358.11 OAG04103.1 - 0.073 13.0 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) ArfGap PF01412.18 OAG04104.1 - 3.9e-33 114.0 0.4 6.3e-33 113.3 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.8 OAG04104.1 - 0.078 13.0 0.6 0.19 11.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MFS_1 PF07690.16 OAG04105.1 - 1e-19 70.7 31.7 1e-19 70.7 31.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04105.1 - 0.00058 18.8 5.2 0.00058 18.8 5.2 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter Pectinesterase PF01095.19 OAG04106.1 - 7.1e-47 159.6 9.0 9.3e-47 159.2 9.0 1.1 1 0 0 1 1 1 1 Pectinesterase CW_7 PF08230.11 OAG04106.1 - 0.055 13.2 0.3 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 CW_7 repeat MFS_1 PF07690.16 OAG04107.1 - 1e-42 146.4 62.4 1.5e-42 145.8 59.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG04107.1 - 4.1e-10 38.7 34.6 5.9e-10 38.2 34.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG04107.1 - 5.7e-08 32.1 15.3 5.7e-08 32.1 15.3 3.2 1 1 1 3 3 3 2 Sugar (and other) transporter FAM70 PF14967.6 OAG04107.1 - 8 5.8 9.6 0.4 10.1 2.2 2.1 2 0 0 2 2 2 0 FAM70 protein DUF829 PF05705.14 OAG04108.1 - 2.1e-50 171.9 0.0 3.3e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_1 PF00561.20 OAG04109.1 - 1.2e-13 51.3 0.1 2e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG04109.1 - 1.8e-12 48.4 8.1 3e-12 47.6 8.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG04109.1 - 2e-09 37.1 0.1 3.3e-08 33.1 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 OAG04109.1 - 0.0062 16.2 0.0 0.056 13.1 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ser_hydrolase PF06821.13 OAG04109.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 OAG04109.1 - 0.1 12.4 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAG04109.1 - 0.16 11.8 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Smr PF01713.21 OAG04109.1 - 0.16 12.3 0.5 0.86 10.0 0.0 2.3 3 1 0 3 3 3 0 Smr domain DUF3394 PF11874.8 OAG04110.1 - 0.057 13.1 0.3 0.061 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) gpUL132 PF11359.8 OAG04110.1 - 0.089 12.3 0.4 0.091 12.3 0.4 1.0 1 0 0 1 1 1 0 Glycoprotein UL132 ATP-synt_8 PF00895.20 OAG04110.1 - 0.67 10.5 3.8 0.42 11.1 0.8 1.9 1 1 1 2 2 2 0 ATP synthase protein 8 MucBP PF06458.12 OAG04111.1 - 3 8.9 13.2 7.5 7.6 5.6 2.9 3 0 0 3 3 3 0 MucBP domain Telomere_reg-2 PF10193.9 OAG04112.1 - 0.12 12.8 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Telomere length regulation protein PfkB PF00294.24 OAG04114.1 - 4.3e-72 243.0 1.6 4.9e-72 242.8 1.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAG04114.1 - 2.8e-05 23.6 0.0 0.00012 21.6 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Fer2_3 PF13085.6 OAG04114.1 - 0.19 11.8 0.1 0.44 10.6 0.0 1.6 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain CorA PF01544.18 OAG04115.1 - 7.5e-13 48.4 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4381 PF14316.6 OAG04115.1 - 0.036 14.3 0.4 0.09 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2207 PF09972.9 OAG04115.1 - 0.058 12.2 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 OAG04115.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4227 PF14004.6 OAG04115.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) zf-C2H2 PF00096.26 OAG04116.1 - 0.19 12.2 0.4 0.19 12.2 0.4 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type EST1_DNA_bind PF10373.9 OAG04117.1 - 1.6e-67 227.9 0.0 2.3e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 OAG04117.1 - 2.3e-17 63.9 3.1 4.4e-17 63.0 2.3 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 UBX PF00789.20 OAG04118.1 - 7.6e-12 45.3 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAG04118.1 - 6.3e-11 41.9 0.1 1.4e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain SUB1_ProdP9 PF18213.1 OAG04118.1 - 0.076 12.9 0.1 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 DUF1682 PF07946.14 OAG04118.1 - 0.096 11.9 5.7 0.11 11.7 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 OAG04118.1 - 2.1 7.9 12.2 3.3 7.3 12.2 1.2 1 0 0 1 1 1 0 DDRGK domain FAD_binding_4 PF01565.23 OAG04119.1 - 1.1e-19 70.5 0.5 2.1e-19 69.6 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG04119.1 - 3.9e-08 33.3 0.0 7.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.19 OAG04119.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Glyco_hydro_43 PF04616.14 OAG04120.1 - 2.1e-38 132.3 0.8 2.4e-38 132.1 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAG04120.1 - 0.0025 17.4 1.5 0.0056 16.3 1.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Peptidase_S28 PF05577.12 OAG04122.1 - 4.2e-47 160.9 1.7 4.9e-46 157.4 1.7 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 TPR_10 PF13374.6 OAG04125.1 - 2e-24 84.7 13.8 5.2e-09 35.7 3.4 5.6 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG04125.1 - 1e-23 83.4 24.2 1.7e-10 41.0 2.8 4.7 1 1 3 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.22 OAG04125.1 - 5.7e-06 25.7 0.0 1.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 OAG04125.1 - 0.00042 20.1 0.3 0.37 10.9 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat NACHT PF05729.12 OAG04125.1 - 0.00051 20.0 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG04125.1 - 0.0016 18.9 0.8 0.011 16.1 0.8 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OAG04125.1 - 0.0062 16.1 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 OAG04125.1 - 0.012 15.4 11.7 5.4 7.0 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PAC3 PF10178.9 OAG04125.1 - 0.14 12.3 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 HAD_2 PF13419.6 OAG04126.1 - 9.4e-09 35.6 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG04126.1 - 1.4e-05 25.5 0.0 2.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG04126.1 - 0.00087 19.3 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like CT_A_B PF02626.15 OAG04127.1 - 5.7e-79 265.5 0.0 1.2e-78 264.4 0.0 1.5 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 OAG04127.1 - 3.7e-54 183.4 0.0 8e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG04127.1 - 3.4e-35 120.9 0.2 4.2e-34 117.4 0.2 2.6 2 1 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 OAG04127.1 - 6.5e-35 120.7 0.0 1.3e-34 119.7 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 OAG04127.1 - 4.9e-30 103.8 0.0 1e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG04127.1 - 3.6e-07 29.9 1.3 1.5e-06 28.0 1.3 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG04127.1 - 2.6e-06 27.1 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG04127.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAG04127.1 - 0.028 14.2 0.1 5.3 7.0 0.1 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like LamB_YcsF PF03746.16 OAG04128.1 - 4.1e-84 282.0 0.0 4.6e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family FAD_binding_4 PF01565.23 OAG04129.1 - 1.5e-16 60.4 0.1 2.3e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG04129.1 - 0.13 12.4 1.3 0.23 11.6 0.3 1.9 2 0 0 2 2 2 0 Berberine and berberine like Thymidylat_synt PF00303.19 OAG04130.1 - 8.6e-107 356.2 0.0 9.9e-107 356.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF16 PF01519.16 OAG04131.1 - 0.42 11.1 0.1 0.42 11.1 0.1 3.9 3 2 0 3 3 3 0 Protein of unknown function DUF16 MitMem_reg PF13012.6 OAG04131.1 - 2.4 8.6 9.9 0.85 10.1 0.6 3.6 2 2 1 3 3 3 0 Maintenance of mitochondrial structure and function Pex14_N PF04695.13 OAG04134.1 - 0.019 15.7 0.1 0.024 15.3 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3802 PF12290.8 OAG04134.1 - 0.093 13.2 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) DUF948 PF06103.11 OAG04134.1 - 0.11 12.7 0.2 0.22 11.8 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DPBB_1 PF03330.18 OAG04136.1 - 4.8e-06 26.8 0.0 9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAG04136.1 - 0.00061 19.6 0.1 0.00092 19.1 0.1 1.2 1 0 0 1 1 1 1 Barwin family CUE PF02845.16 OAG04137.1 - 9.2e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 OAG04137.1 - 0.41 10.3 6.7 0.92 9.2 6.7 1.5 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) DUF3602 PF12223.8 OAG04138.1 - 0.037 14.6 0.1 0.043 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) DUF5619 PF18505.1 OAG04138.1 - 0.052 13.5 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) SKG6 PF08693.10 OAG04140.1 - 0.54 9.7 7.0 1.4 8.4 7.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lyase_aromatic PF00221.19 OAG04141.1 - 7.5e-109 364.5 4.9 1e-108 364.0 4.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase MFS_1 PF07690.16 OAG04143.1 - 3.3e-33 115.1 28.1 4.6e-33 114.6 28.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3593 PF12159.8 OAG04143.1 - 0.032 14.3 0.8 0.17 11.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) DUF3671 PF12420.8 OAG04143.1 - 0.069 13.2 0.1 2.5 8.2 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function ESSS PF10183.9 OAG04143.1 - 0.085 13.1 0.1 0.25 11.6 0.1 1.8 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) OSTbeta PF15048.6 OAG04143.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2776 PF10951.8 OAG04143.1 - 0.39 9.9 10.5 0.79 8.9 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2776) bZIP_1 PF00170.21 OAG04144.1 - 1.8e-07 31.1 7.7 1.8e-07 31.1 7.7 1.8 2 0 0 2 2 2 1 bZIP transcription factor SHE3 PF17078.5 OAG04144.1 - 0.003 17.3 2.5 0.0038 17.0 2.5 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 PspA_IM30 PF04012.12 OAG04144.1 - 0.0062 16.1 6.6 0.0092 15.6 6.6 1.1 1 0 0 1 1 1 1 PspA/IM30 family bZIP_Maf PF03131.17 OAG04144.1 - 0.018 15.6 8.0 0.033 14.7 8.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG04144.1 - 0.026 14.6 13.0 0.1 12.7 13.0 2.0 1 1 0 1 1 1 0 Basic region leucine zipper Amino_oxidase PF01593.24 OAG04144.1 - 0.12 11.7 0.3 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF1488 PF07369.11 OAG04144.1 - 0.15 12.1 0.4 0.37 10.8 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1488) V_ATPase_I PF01496.19 OAG04144.1 - 0.15 9.9 3.0 0.18 9.7 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NYD-SP28 PF14772.6 OAG04144.1 - 0.52 10.4 8.2 1.5 8.9 8.4 1.7 1 1 1 2 2 2 0 Sperm tail YabA PF06156.13 OAG04144.1 - 0.94 10.1 3.3 1 10.1 2.1 1.6 1 1 1 2 2 2 0 Initiation control protein YabA SlyX PF04102.12 OAG04144.1 - 4.3 8.0 6.5 1.1 9.9 1.8 2.3 1 1 1 2 2 2 0 SlyX EHD_N PF16880.5 OAG04145.1 - 0.058 13.3 0.0 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 N-terminal EH-domain containing protein Peptidase_M28 PF04389.17 OAG04146.1 - 3.9e-37 127.9 0.0 5.4e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG04146.1 - 2.3e-10 40.4 0.1 6.4e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG04146.1 - 0.0045 16.7 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.16 OAG04147.1 - 1.7e-33 116.0 27.0 1.7e-33 116.0 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04147.1 - 3e-08 33.0 9.2 3.9e-07 29.3 1.4 3.6 2 1 2 5 5 5 2 Sugar (and other) transporter TRI12 PF06609.13 OAG04147.1 - 7.5e-06 24.6 1.7 7.5e-06 24.6 1.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAG04147.1 - 0.0016 16.9 2.3 0.0016 16.9 2.3 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector Gly-zipper_Omp PF13488.6 OAG04147.1 - 3.7 7.6 6.7 15 5.7 6.7 2.0 1 1 0 1 1 1 0 Glycine zipper GMC_oxred_N PF00732.19 OAG04148.1 - 1.2e-24 87.2 0.0 2.4e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG04148.1 - 2.6e-22 79.9 0.1 5e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG04148.1 - 7.3e-10 38.5 0.1 0.00026 20.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG04148.1 - 6.2e-05 22.7 0.8 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG04148.1 - 7.5e-05 22.9 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG04148.1 - 0.0073 15.6 0.0 0.016 14.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG04148.1 - 0.012 14.3 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 OAG04148.1 - 0.018 14.4 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG04148.1 - 0.079 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG04148.1 - 0.095 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG04148.1 - 0.14 12.7 0.0 25 5.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sortilin-Vps10 PF15902.5 OAG04149.1 - 8.5e-10 38.0 5.3 5.6e-08 32.0 0.1 3.2 1 1 0 3 3 3 2 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 OAG04149.1 - 8.1e-08 31.9 14.0 0.0037 16.6 0.3 4.9 1 1 4 5 5 5 5 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 OAG04149.1 - 1.6e-07 30.2 29.2 1.2 9.5 0.1 7.2 7 0 0 7 7 7 5 BNR/Asp-box repeat BNR_2 PF13088.6 OAG04149.1 - 7e-06 25.6 4.5 2.4e-05 23.8 1.2 2.7 1 1 2 3 3 3 2 BNR repeat-like domain CHB_HEX_C PF03174.13 OAG04149.1 - 0.0073 16.3 5.0 7.1 6.7 0.1 4.7 5 0 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain FAD_binding_4 PF01565.23 OAG04150.1 - 1.6e-15 57.0 0.1 1.8e-12 47.2 0.1 2.4 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.12 OAG04150.1 - 0.00081 19.4 0.1 0.0092 16.1 0.0 2.6 2 0 0 2 2 2 1 Berberine and berberine like DUF746 PF05344.11 OAG04150.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Lon_C PF05362.13 OAG04151.1 - 1.3e-64 217.5 0.0 2.3e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAG04151.1 - 3.2e-32 112.1 0.0 7.2e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAG04151.1 - 8e-22 78.1 0.0 1.9e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG04151.1 - 3.9e-06 26.9 0.0 7.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG04151.1 - 6.4e-06 26.5 0.1 0.00017 21.9 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OAG04151.1 - 1e-05 25.7 0.0 3.4e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 OAG04151.1 - 1.7e-05 23.9 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 OAG04151.1 - 2.9e-05 23.9 0.0 7.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 OAG04151.1 - 9.4e-05 22.8 0.2 0.00098 19.5 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAG04151.1 - 0.00014 21.6 0.1 0.00084 19.1 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG04151.1 - 0.0049 17.4 1.0 0.035 14.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 OAG04151.1 - 0.0052 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG04151.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG04151.1 - 0.032 14.0 0.0 0.078 12.7 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OAG04151.1 - 0.062 13.2 0.1 0.61 10.0 0.0 2.4 1 1 1 2 2 2 0 NTPase F-box-like_2 PF13013.6 OAG04151.1 - 0.073 13.1 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain AAA_7 PF12775.7 OAG04151.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG04151.1 - 0.19 12.2 0.0 0.46 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 OAG04151.1 - 0.25 11.5 3.9 0.54 10.4 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase RsgA_GTPase PF03193.16 OAG04151.1 - 0.37 10.7 0.0 0.37 10.7 0.0 2.1 3 0 0 3 3 2 0 RsgA GTPase Cytidylate_kin PF02224.18 OAG04151.1 - 1.3 8.7 5.1 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase DUF445 PF04286.12 OAG04152.1 - 0.0046 16.8 0.1 0.03 14.1 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF445) NUDIX PF00293.28 OAG04153.1 - 4.7e-21 75.2 0.2 5.8e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain SLT PF01464.20 OAG04155.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Transglycosylase SLT domain Xpo1 PF08389.12 OAG04156.1 - 1e-28 100.3 2.4 1.2e-27 96.8 0.3 3.8 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 OAG04156.1 - 2e-06 27.6 0.1 7.3e-06 25.8 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 OAG04156.1 - 1.6e-05 25.3 2.2 0.0013 19.2 0.0 4.6 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 OAG04156.1 - 0.00014 22.2 0.1 0.0025 18.2 0.0 3.2 3 1 0 3 3 3 1 HEAT repeats FANCI_S1 PF14675.6 OAG04156.1 - 0.041 13.5 1.0 0.2 11.2 0.1 2.4 3 0 0 3 3 3 0 FANCI solenoid 1 Adaptin_N PF01602.20 OAG04156.1 - 0.16 10.5 0.2 3 6.3 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region RNA_polI_A14 PF08203.11 OAG04156.1 - 0.17 12.6 0.1 0.47 11.2 0.1 1.7 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 HEAT PF02985.22 OAG04156.1 - 0.23 11.8 1.5 19 5.8 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat LSM PF01423.22 OAG04157.1 - 4e-16 58.5 0.1 4.9e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAG04157.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Hfq protein 5-FTHF_cyc-lig PF01812.20 OAG04158.1 - 1e-35 123.3 0.0 1.4e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.9 OAG04159.1 - 6.9e-94 313.2 0.3 8e-94 313.0 0.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Peptidase_M24 PF00557.24 OAG04160.1 - 1.5e-59 201.2 0.0 2.3e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAG04160.1 - 9.4e-24 83.5 0.0 1.6e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Tubulin_3 PF14881.6 OAG04163.1 - 1.9e-74 249.3 0.0 3.1e-74 248.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 OAG04163.1 - 1.7e-40 138.0 0.0 3.9e-40 136.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 OAG04163.1 - 4.4e-05 23.8 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Prp18 PF02840.15 OAG04164.1 - 6.1e-57 191.7 0.1 6.1e-57 191.7 0.1 1.8 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 OAG04164.1 - 2.4e-11 43.0 0.4 2.4e-11 43.0 0.4 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Amidohydro_2 PF04909.14 OAG04164.1 - 0.0071 16.2 2.9 2.5 7.8 2.1 2.1 2 0 0 2 2 2 2 Amidohydrolase Borrelia_P83 PF05262.11 OAG04164.1 - 1.4 7.3 14.7 1.9 6.9 14.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.10 OAG04164.1 - 5.3 6.3 23.9 8.5 5.6 23.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 OAG04164.1 - 5.5 5.2 17.5 8.5 4.5 17.5 1.3 1 0 0 1 1 1 0 CDC45-like protein SAP18 PF06487.12 OAG04165.1 - 3.2e-50 170.0 0.0 3.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Abhydrolase_6 PF12697.7 OAG04166.1 - 0.0038 17.9 0.1 0.0038 17.9 0.1 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family LCAT PF02450.15 OAG04166.1 - 0.023 13.9 0.0 0.052 12.7 0.0 1.6 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OAG04166.1 - 0.024 13.9 0.0 0.098 11.9 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAG04166.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Palm_thioest PF02089.15 OAG04166.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 OAG04166.1 - 0.21 11.1 0.1 0.33 10.4 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ada_Zn_binding PF02805.16 OAG04167.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Metal binding domain of Ada Glyco_tranf_2_3 PF13641.6 OAG04168.1 - 6.2e-15 55.7 0.0 2.9e-14 53.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DPM3 PF08285.11 OAG04168.1 - 3.1 8.0 7.8 5 7.4 1.5 2.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MFS_1 PF07690.16 OAG04169.1 - 3.2e-33 115.1 27.8 6.1e-33 114.2 25.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily eRF1_1 PF03463.15 OAG04170.1 - 0.012 15.6 0.2 0.02 14.9 0.2 1.3 1 0 0 1 1 1 0 eRF1 domain 1 Ndc1_Nup PF09531.10 OAG04170.1 - 0.17 10.5 5.0 0.19 10.4 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UQ_con PF00179.26 OAG04172.1 - 1.8e-13 50.4 0.0 5.1e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme F-box PF00646.33 OAG04172.1 - 1.6e-05 24.7 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain RWD PF05773.22 OAG04172.1 - 0.001 19.3 0.1 0.0024 18.1 0.1 1.6 1 0 0 1 1 1 1 RWD domain F-box-like PF12937.7 OAG04172.1 - 0.015 15.2 0.1 0.042 13.8 0.1 1.8 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 OAG04173.1 - 2.2e-38 132.1 41.8 2.2e-38 132.1 41.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04173.1 - 5e-11 42.1 11.7 5e-11 42.1 11.7 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Ribosomal_S17_N PF16205.5 OAG04174.1 - 2.8e-33 114.1 0.2 4.5e-33 113.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OAG04174.1 - 5.6e-26 90.5 0.3 1e-25 89.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 adh_short PF00106.25 OAG04175.1 - 6.5e-40 136.7 0.0 8.5e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04175.1 - 8.3e-25 87.7 0.0 1.1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04175.1 - 3e-05 24.0 0.0 8.1e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG04175.1 - 0.04 13.0 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG04175.1 - 0.087 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG04175.1 - 0.13 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Erg28 PF03694.13 OAG04176.1 - 5e-41 139.5 0.1 6.2e-41 139.2 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein TadE PF07811.12 OAG04176.1 - 0.12 12.6 1.7 0.77 10.1 0.1 2.3 2 0 0 2 2 2 0 TadE-like protein GalP_UDP_transf PF01087.22 OAG04177.1 - 2e-68 230.5 0.2 1.7e-66 224.1 0.0 2.7 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 OAG04177.1 - 1.7e-61 206.8 0.2 6.5e-61 204.9 0.2 1.9 1 1 1 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 OAG04177.1 - 0.082 13.6 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 HIT domain Yip1 PF04893.17 OAG04178.1 - 1.4e-10 41.1 14.5 2.1e-10 40.6 14.4 1.4 1 1 0 1 1 1 1 Yip1 domain Ran_BP1 PF00638.18 OAG04179.1 - 1.6e-16 60.6 0.0 2.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain ABC_tran PF00005.27 OAG04180.1 - 8.7e-52 175.3 0.0 2.8e-26 92.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG04180.1 - 1.1e-29 103.9 16.7 2.5e-22 79.8 4.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 OAG04180.1 - 5.5e-13 49.6 0.3 4e-06 27.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG04180.1 - 1.1e-11 45.2 3.3 0.014 15.2 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG04180.1 - 3.9e-11 42.8 2.5 0.0032 16.9 0.2 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG04180.1 - 5.7e-08 33.1 0.2 0.0055 17.0 0.0 3.8 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 OAG04180.1 - 3.2e-07 29.8 0.0 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF87 PF01935.17 OAG04180.1 - 3.4e-07 30.6 1.8 2.3e-05 24.6 0.3 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 OAG04180.1 - 4.3e-06 26.4 2.7 0.054 13.2 0.3 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 OAG04180.1 - 6.2e-06 25.5 0.3 0.039 13.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 OAG04180.1 - 1e-05 26.1 2.5 0.0038 17.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG04180.1 - 1.1e-05 25.2 0.1 0.064 13.0 0.0 2.6 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 OAG04180.1 - 7.9e-05 22.7 0.3 0.57 10.3 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 OAG04180.1 - 0.00014 22.2 0.3 0.03 14.7 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAG04180.1 - 0.0002 21.9 0.1 0.013 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG04180.1 - 0.0003 20.4 0.2 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 OAG04180.1 - 0.00077 19.2 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 OAG04180.1 - 0.00088 19.2 0.3 0.83 9.5 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Viral_helicase1 PF01443.18 OAG04180.1 - 0.001 18.9 0.2 0.035 13.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 OAG04180.1 - 0.002 18.1 1.5 0.01 15.8 0.0 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain NACHT PF05729.12 OAG04180.1 - 0.0023 17.8 2.3 0.32 10.9 0.1 3.2 3 0 0 3 3 3 1 NACHT domain cobW PF02492.19 OAG04180.1 - 0.0026 17.4 0.4 0.21 11.2 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 OAG04180.1 - 0.0028 17.3 2.7 0.99 8.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_11 PF13086.6 OAG04180.1 - 0.0039 17.0 0.1 0.09 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG04180.1 - 0.0043 17.2 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAG04180.1 - 0.0054 16.7 1.0 0.1 12.5 0.1 2.6 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.14 OAG04180.1 - 0.0081 16.2 0.1 6.1 6.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAG04180.1 - 0.0081 16.5 0.2 0.79 10.1 0.0 2.7 3 0 0 3 3 2 1 RNA helicase ATPase_2 PF01637.18 OAG04180.1 - 0.011 15.7 0.3 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 OAG04180.1 - 0.013 14.4 0.3 0.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.6 OAG04180.1 - 0.015 15.5 0.6 1.7 8.9 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 OAG04180.1 - 0.016 15.6 1.7 0.46 10.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 OAG04180.1 - 0.018 15.1 0.4 0.18 11.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 OAG04180.1 - 0.019 13.9 0.7 0.096 11.7 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 OAG04180.1 - 0.027 14.7 2.3 0.091 13.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAG04180.1 - 0.028 13.8 0.3 0.072 12.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 OAG04180.1 - 0.034 13.4 0.1 8.2 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 OAG04180.1 - 0.044 13.5 0.4 2.8 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAG04180.1 - 0.046 13.7 0.1 0.35 10.9 0.0 2.4 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OAG04180.1 - 0.053 13.2 0.2 14 5.4 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 OAG04180.1 - 0.07 12.9 0.4 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 OAG04180.1 - 0.075 12.7 0.2 5.9 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 OAG04180.1 - 0.077 12.4 0.3 1.7 8.1 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein MobB PF03205.14 OAG04180.1 - 0.09 12.7 0.4 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 OAG04180.1 - 0.092 12.1 1.5 7.1 5.9 0.1 2.8 3 0 0 3 3 2 0 KaiC Adeno_IVa2 PF02456.15 OAG04180.1 - 0.15 10.8 0.7 0.67 8.7 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein GAT PF03127.14 OAG04183.1 - 1.6e-18 66.8 0.6 3.7e-18 65.6 0.3 1.8 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 OAG04183.1 - 0.00028 20.8 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 VHS domain DUF2183 PF09949.9 OAG04184.1 - 8.8e-35 119.0 0.0 5.8e-34 116.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF3328 PF11807.8 OAG04185.1 - 2.8e-18 66.5 0.0 6e-18 65.4 0.0 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Aldo_ket_red PF00248.21 OAG04186.1 - 8.3e-41 140.1 0.1 1.2e-39 136.3 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family NST1 PF13945.6 OAG04187.1 - 0.31 11.1 2.7 0.34 11.0 2.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Cytochrom_B561 PF03188.16 OAG04188.1 - 1.7e-05 24.9 9.7 2.6e-05 24.4 9.7 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 OAG04188.1 - 0.0021 17.8 7.9 0.0038 17.0 7.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Tetraspanin PF00335.20 OAG04188.1 - 0.077 12.7 2.5 0.13 12.0 2.5 1.4 1 0 0 1 1 1 0 Tetraspanin family TarH PF02203.15 OAG04189.1 - 0.099 12.6 1.6 2 8.3 0.1 2.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue WD40 PF00400.32 OAG04190.1 - 0.0001 23.0 7.3 0.095 13.6 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG04190.1 - 0.0039 17.4 0.8 0.91 9.9 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2157 PF09925.9 OAG04195.1 - 0.00017 21.4 2.1 0.00041 20.2 2.1 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) Acetyltransf_1 PF00583.25 OAG04196.1 - 7.7e-09 35.8 0.2 1.2e-08 35.2 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG04196.1 - 1.6e-06 28.4 0.0 2.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG04196.1 - 1.7e-05 24.8 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG04196.1 - 0.015 15.4 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG04196.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HET PF06985.11 OAG04197.1 - 6.5e-33 114.1 4.4 6.5e-33 114.1 4.4 3.2 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Auts2 PF15336.6 OAG04197.1 - 0.39 10.8 9.0 0.015 15.4 2.4 2.0 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein TruD PF01142.18 OAG04198.1 - 3.4e-56 190.9 0.4 4.6e-52 177.2 0.1 3.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Pectate_lyase_3 PF12708.7 OAG04199.1 - 4.7e-93 310.9 20.7 2.3e-84 282.6 8.2 2.8 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG04199.1 - 3.6e-06 26.6 4.0 0.037 13.7 0.4 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 OAG04199.1 - 0.004 17.0 7.8 0.004 17.0 7.8 2.2 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 OAG04199.1 - 0.014 14.7 0.8 0.014 14.7 0.8 2.2 2 1 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Aminotran_1_2 PF00155.21 OAG04201.1 - 4.7e-19 68.8 0.0 6e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAG04201.1 - 0.002 17.0 0.0 1.6 7.4 0.0 3.0 3 0 0 3 3 3 3 Alanine-glyoxylate amino-transferase Auxin_repressed PF05564.12 OAG04202.1 - 0.36 11.5 5.8 0.56 10.9 0.0 3.1 2 1 1 3 3 3 0 Dormancy/auxin associated protein Mtc PF03820.17 OAG04203.1 - 4.1e-124 413.7 0.0 4.6e-124 413.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier HSP70 PF00012.20 OAG04204.1 - 1.2e-65 221.8 7.9 1.3e-60 205.3 0.1 3.8 3 1 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 OAG04204.1 - 0.0036 16.2 0.1 0.014 14.2 0.1 2.0 1 0 0 1 1 1 1 MreB/Mbl protein Top6b_C PF18000.1 OAG04204.1 - 0.057 13.6 0.2 12 6.1 0.1 2.7 2 0 0 2 2 2 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Ketoacyl-synt_C PF02801.22 OAG04204.1 - 0.86 9.6 4.0 10 6.2 0.0 3.6 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain MOSC PF03473.17 OAG04205.1 - 7.2e-25 87.5 0.0 1.8e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 OAG04205.1 - 2.3e-08 33.9 3.3 4.8e-08 32.8 3.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 OAG04205.1 - 0.0034 17.2 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 OAG04205.1 - 0.0042 17.7 0.0 0.077 13.6 0.1 2.8 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG04205.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF730 PF05325.11 OAG04206.1 - 0.091 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF730) SnoaL PF07366.12 OAG04207.1 - 0.025 14.4 0.1 0.33 10.8 0.0 2.0 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase Sugar_tr PF00083.24 OAG04208.1 - 5.1e-84 282.7 22.2 5.9e-84 282.5 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG04208.1 - 1e-17 64.2 29.7 1.6e-17 63.5 25.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily SPRY PF00622.28 OAG04209.1 - 1.8e-19 70.0 0.1 3e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Pex14_N PF04695.13 OAG04209.1 - 0.53 10.9 7.4 0.8 10.4 2.3 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.16 OAG04210.1 - 2.8e-29 102.1 27.2 2.8e-29 102.1 27.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ADH_N PF08240.12 OAG04211.1 - 4.7e-24 84.4 0.0 1e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG04211.1 - 2.4e-23 82.6 0.9 3.9e-23 81.9 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG04211.1 - 3.7e-07 31.3 0.0 5.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 OAG04212.1 - 1.1e-32 113.4 0.5 2.1e-32 112.5 0.5 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAG04212.1 - 2.9e-11 43.8 0.2 7.2e-11 42.5 0.1 1.7 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 OAG04212.1 - 3.4e-10 40.2 0.5 2.8e-09 37.3 0.1 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 OAG04212.1 - 5.5e-09 36.2 0.1 1.4e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG04212.1 - 6.2e-05 22.7 0.4 0.00019 21.1 0.4 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 OAG04212.1 - 0.00063 19.7 0.3 0.00063 19.7 0.3 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG04212.1 - 0.00095 19.6 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.12 OAG04212.1 - 0.0035 16.9 0.2 0.008 15.8 0.1 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ADH_zinc_N PF00107.26 OAG04212.1 - 0.011 15.7 1.5 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase KR PF08659.10 OAG04212.1 - 0.021 14.7 0.3 0.045 13.7 0.1 1.6 2 0 0 2 2 2 0 KR domain GFO_IDH_MocA PF01408.22 OAG04212.1 - 0.037 14.9 0.1 0.081 13.8 0.0 1.6 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 OAG04212.1 - 0.048 13.9 0.6 0.11 12.8 0.1 1.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAG04212.1 - 0.053 13.8 1.2 0.19 12.0 1.2 1.9 1 1 0 1 1 1 0 TrkA-N domain CbiK PF06180.11 OAG04212.1 - 0.053 12.8 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) NAT PF04768.13 OAG04213.1 - 2.7e-51 173.6 0.0 1.2e-50 171.5 0.0 1.9 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase LZ_Tnp_IS66 PF13007.7 OAG04213.1 - 1.7 9.5 8.4 0.63 10.9 2.2 2.8 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain SnoaL_4 PF13577.6 OAG04216.1 - 2.9e-21 75.9 0.0 3.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG04216.1 - 0.03 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Glyco_hydro_7 PF00840.20 OAG04217.1 - 6.1e-121 404.2 19.5 6.1e-121 404.2 19.5 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 OAG04217.1 - 6.8e-14 51.5 9.3 6.8e-14 51.5 9.3 4.2 4 1 0 4 4 4 1 Fungal cellulose binding domain Fer4_20 PF14691.6 OAG04217.1 - 0.29 10.9 3.5 0.41 10.4 0.1 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Mpv17_PMP22 PF04117.12 OAG04218.1 - 0.037 14.3 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 Mpv17 / PMP22 family DUF1388 PF07142.12 OAG04218.1 - 0.079 12.9 5.9 0.13 12.2 5.9 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) DUF2124 PF09897.9 OAG04218.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) BLOC1_2 PF10046.9 OAG04219.1 - 0.018 15.4 0.3 0.018 15.4 0.3 2.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 OAG04219.1 - 4.4 7.7 6.8 0.32 11.3 0.6 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain PigN PF04987.14 OAG04220.1 - 1.6e-149 498.7 32.4 1.6e-149 498.7 32.4 1.6 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 OAG04220.1 - 4.1e-07 29.9 4.4 6.1e-06 26.1 2.2 2.2 1 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG04220.1 - 1e-06 28.4 0.1 1.6e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 OAG04220.1 - 0.0025 17.2 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily GDI PF00996.18 OAG04221.1 - 7.7e-173 575.0 0.0 9.8e-173 574.6 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OAG04221.1 - 0.0085 16.3 0.1 0.026 14.8 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.13 OAG04222.1 - 1.6e-18 66.5 0.3 2.5e-18 66.0 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) bZIP_2 PF07716.15 OAG04223.1 - 1.9e-07 31.1 8.5 2.1e-07 30.9 8.2 1.4 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAG04223.1 - 2.5e-05 24.3 6.9 3.2e-05 24.0 6.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OAG04223.1 - 0.0003 21.2 6.1 0.00034 21.1 6.1 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor TPD52 PF04201.15 OAG04223.1 - 0.00067 19.3 0.4 0.00071 19.2 0.4 1.1 1 0 0 1 1 1 1 Tumour protein D52 family WD40_alt PF14077.6 OAG04223.1 - 0.009 15.9 0.2 0.012 15.4 0.2 1.3 1 0 0 1 1 1 1 Alternative WD40 repeat motif CLZ PF16526.5 OAG04223.1 - 0.015 15.7 1.0 0.022 15.1 0.7 1.3 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1635 PF07795.11 OAG04223.1 - 0.017 15.0 2.0 0.018 14.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4110 PF13422.6 OAG04223.1 - 0.037 14.1 0.9 0.045 13.8 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) Spc29 PF17082.5 OAG04223.1 - 0.04 13.8 1.0 0.039 13.8 1.0 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF4349 PF14257.6 OAG04223.1 - 0.053 13.0 2.4 0.053 13.0 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Sec2p PF06428.11 OAG04223.1 - 0.084 12.9 3.2 1.2 9.1 1.5 2.0 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Bap31_Bap29_C PF18035.1 OAG04223.1 - 0.12 12.4 2.7 0.39 10.8 0.5 2.1 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain HAUS-augmin3 PF14932.6 OAG04223.1 - 0.27 10.8 4.0 0.26 10.8 4.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NOT2_3_5 PF04153.18 OAG04225.1 - 1.6e-26 92.9 0.3 2.9e-26 92.1 0.3 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family HET PF06985.11 OAG04226.1 - 4.6e-23 82.2 0.0 1.2e-22 80.8 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2561 PF10812.8 OAG04226.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) MFS_1 PF07690.16 OAG04227.1 - 6e-29 101.1 32.1 6e-29 101.1 32.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04227.1 - 7.5e-08 31.7 3.9 7.5e-08 31.7 3.9 3.6 2 1 2 4 4 4 2 Sugar (and other) transporter Lactamase_B PF00753.27 OAG04228.1 - 0.00034 20.7 0.1 0.00078 19.5 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BRX_assoc PF16627.5 OAG04228.1 - 0.06 13.5 0.8 0.44 10.7 0.2 2.2 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain Lactamase_B_2 PF12706.7 OAG04228.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF3237 PF11578.8 OAG04229.1 - 2.2e-24 86.0 0.3 2.9e-19 69.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) MFS_1 PF07690.16 OAG04230.1 - 4e-28 98.4 25.3 5e-28 98.0 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04230.1 - 8.2e-06 24.9 5.5 8.2e-06 24.9 5.5 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Glt_symporter PF03616.14 OAG04230.1 - 0.0041 15.9 2.5 0.0065 15.2 2.5 1.2 1 0 0 1 1 1 1 Sodium/glutamate symporter BT1 PF03092.16 OAG04230.1 - 0.017 13.3 0.1 0.059 11.6 0.0 1.8 2 0 0 2 2 2 0 BT1 family HAUS6_N PF14661.6 OAG04231.1 - 1.1e-46 159.3 1.0 2e-46 158.5 1.0 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF2405 PF10293.9 OAG04231.1 - 0.17 11.9 0.9 0.45 10.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2405) HD_3 PF13023.6 OAG04232.1 - 2.7e-33 115.2 0.0 3.3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OAG04232.1 - 6.2e-07 29.4 0.0 8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme WD40 PF00400.32 OAG04236.1 - 1.7e-14 54.0 4.3 0.0038 18.0 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG04236.1 - 3.8e-05 23.9 1.2 0.093 13.0 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Glycos_transf_4 PF00953.21 OAG04237.1 - 5.6e-31 107.7 11.0 5.6e-31 107.7 11.0 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 4 SNARE_assoc PF09335.11 OAG04237.1 - 0.063 13.8 0.6 0.063 13.8 0.6 3.4 3 1 0 3 3 3 0 SNARE associated Golgi protein Aconitase PF00330.20 OAG04238.1 - 2e-161 538.1 0.0 2.4e-161 537.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG04238.1 - 1.3e-40 138.8 0.0 2.2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain CDC73_C PF05179.14 OAG04239.1 - 8.9e-53 178.2 0.0 1.3e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Acyl-CoA_dh_1 PF00441.24 OAG04239.1 - 0.05 13.8 0.2 0.083 13.1 0.2 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ECM11 PF15463.6 OAG04240.1 - 4.7e-37 127.6 1.2 4.7e-37 127.6 1.2 2.2 2 1 0 2 2 2 1 Extracellular mutant protein 11 CNDH2_C PF16858.5 OAG04240.1 - 1.8 8.4 14.8 7.3 6.4 8.4 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 OAG04240.1 - 2.9 6.0 20.0 4.8 5.3 20.0 1.2 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.7 OAG04241.1 - 0.00084 19.2 1.0 0.0017 18.2 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAG04241.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 F-box Ribosomal_S11 PF00411.19 OAG04241.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S11 p450 PF00067.22 OAG04242.1 - 1.2e-46 159.4 0.0 1.8e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Reo_sigmaC PF04582.12 OAG04242.1 - 0.46 10.7 1.7 7.1 6.9 0.1 2.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein C-terminal domain PhoR PF11808.8 OAG04242.1 - 0.95 9.9 7.8 4.3 7.8 1.4 2.7 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR NMO PF03060.15 OAG04243.1 - 9.3e-58 196.2 0.3 1.3e-57 195.7 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG04243.1 - 6.7e-09 35.2 0.8 1.6e-08 33.9 0.8 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG04243.1 - 0.00046 19.3 1.1 0.00085 18.4 1.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Radial_spoke_3 PF06098.11 OAG04243.1 - 0.081 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 DHO_dh PF01180.21 OAG04243.1 - 0.11 11.6 0.7 0.19 10.9 0.1 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Pterin_bind PF00809.22 OAG04244.1 - 7.1e-85 284.6 0.0 9.2e-85 284.2 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 OAG04244.1 - 2e-37 128.1 0.0 4.2e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) TP2 PF01254.18 OAG04244.1 - 0.004 17.8 0.9 0.0076 16.9 0.9 1.4 1 0 0 1 1 1 1 Nuclear transition protein 2 Zn_clus PF00172.18 OAG04246.1 - 7.6e-10 38.8 9.4 1.6e-09 37.7 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG04247.1 - 8.9e-30 103.8 33.5 8.9e-30 103.8 33.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 OAG04247.1 - 8.6e-05 22.6 0.5 0.085 12.9 0.0 3.2 3 1 0 3 3 3 2 Protein of unknown function UL42 PF17638.2 OAG04247.1 - 0.17 11.9 0.4 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 HCMV UL42 Phage_holin_2_4 PF16082.5 OAG04247.1 - 6.3 6.6 7.2 0.66 9.8 1.2 2.5 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Glyco_hydro_31 PF01055.26 OAG04248.1 - 3.7e-96 323.0 0.1 4.5e-96 322.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG04248.1 - 1.2e-10 41.6 0.1 3.7e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Pkinase PF00069.25 OAG04249.1 - 1.6e-14 53.9 0.1 1.9e-13 50.4 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04249.1 - 4.8e-14 52.3 0.0 4.5e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Helicase_C PF00271.31 OAG04250.1 - 6.1e-20 71.6 0.1 8.7e-16 58.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 OAG04250.1 - 4e-17 62.6 0.0 7.9e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 OAG04250.1 - 6.8e-07 29.9 0.2 1.5e-06 28.8 0.2 1.6 1 0 0 1 1 1 1 RecQ zinc-binding UBA_2 PF08587.11 OAG04250.1 - 0.012 15.7 0.1 24 5.1 0.0 3.9 4 0 0 4 4 4 0 Ubiquitin associated domain (UBA) MFS_1 PF07690.16 OAG04251.1 - 2e-19 69.7 47.8 4.2e-10 39.1 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 OAG04251.1 - 1.2 9.5 11.0 0.17 12.2 2.0 3.1 2 1 0 2 2 2 0 Stage V sporulation protein AB p450 PF00067.22 OAG04252.1 - 8.8e-44 150.0 0.0 1.1e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3188 PF11384.8 OAG04252.1 - 0.14 11.9 0.5 0.3 10.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) MTP18 PF10558.9 OAG04253.1 - 1e-79 266.4 0.3 1.5e-79 265.9 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 OAG04254.1 - 1.8e-17 63.5 0.5 2e-17 63.3 0.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Csm1 PF12539.8 OAG04255.1 - 4.2e-30 104.2 1.0 6.8e-30 103.5 0.3 1.7 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Bacillus_HBL PF05791.11 OAG04255.1 - 0.0015 18.4 1.9 0.0015 18.4 1.9 2.4 1 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.6 OAG04255.1 - 0.0015 17.9 15.2 0.034 13.5 8.6 2.8 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding YabA PF06156.13 OAG04255.1 - 0.0015 19.1 8.4 0.0073 16.9 4.6 2.6 1 1 1 2 2 2 1 Initiation control protein YabA DUF5094 PF17015.5 OAG04255.1 - 0.0025 18.0 8.4 0.0036 17.4 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5094) Rootletin PF15035.6 OAG04255.1 - 0.015 15.3 8.6 0.031 14.3 8.6 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 OAG04255.1 - 0.019 14.5 9.0 0.032 13.8 9.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein V_ATPase_I PF01496.19 OAG04255.1 - 0.068 11.1 4.7 0.086 10.7 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-O PF09496.10 OAG04255.1 - 0.09 12.7 2.4 0.14 12.2 2.4 1.5 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component UPF0242 PF06785.11 OAG04255.1 - 0.38 10.8 14.3 0.3 11.1 2.6 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MerR-DNA-bind PF09278.11 OAG04255.1 - 0.41 11.2 5.6 0.84 10.2 1.3 2.6 2 0 0 2 2 2 0 MerR, DNA binding DUF4407 PF14362.6 OAG04255.1 - 0.59 9.4 19.6 0.47 9.7 18.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OAG04255.1 - 0.72 9.7 9.5 0.2 11.4 4.6 2.6 2 1 1 3 3 3 0 Septum formation initiator DUF641 PF04859.12 OAG04255.1 - 0.87 9.9 9.9 0.2 12.0 5.9 2.0 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) TEX13 PF15186.6 OAG04255.1 - 1.2 8.8 7.9 0.93 9.2 6.0 1.9 2 0 0 2 2 1 0 Testis-expressed sequence 13 protein family CLZ PF16526.5 OAG04255.1 - 1.2 9.5 7.9 12 6.3 0.4 3.4 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 OAG04255.1 - 1.5 9.4 5.8 16 6.2 3.9 3.1 2 1 0 2 2 2 0 SlyX Syntaxin-6_N PF09177.11 OAG04255.1 - 1.6 9.4 8.1 0.23 12.0 2.6 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Csm1_N PF18504.1 OAG04255.1 - 3.2 8.2 13.0 12 6.4 2.9 3.8 1 1 3 4 4 4 0 Csm1 N-terminal domain CENP-H PF05837.12 OAG04255.1 - 3.9 7.9 18.4 0.56 10.6 11.0 2.6 1 1 2 3 3 3 0 Centromere protein H (CENP-H) THOC7 PF05615.13 OAG04255.1 - 4 7.7 15.4 6.4 7.1 3.2 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 ABC_tran_CTD PF16326.5 OAG04255.1 - 5.9 7.2 16.1 49 4.3 7.0 3.8 2 2 1 3 3 3 0 ABC transporter C-terminal domain Ax_dynein_light PF10211.9 OAG04255.1 - 7 6.6 15.5 0.73 9.7 1.0 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain PRKG1_interact PF15898.5 OAG04255.1 - 9.5 7.2 17.6 0.67 10.9 8.6 2.8 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 OAG04255.1 - 9.5 6.8 17.3 6.3 7.3 14.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Snf7 PF03357.21 OAG04256.1 - 0.0086 15.7 2.3 1.3 8.6 0.1 2.1 1 1 0 2 2 2 2 Snf7 adh_short PF00106.25 OAG04257.1 - 5.9e-25 87.9 0.0 2e-24 86.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04257.1 - 7.8e-11 42.0 0.0 2.6e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04257.1 - 7.3e-08 32.5 0.5 1.2e-07 31.9 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG04257.1 - 9.1e-07 28.6 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG04257.1 - 0.0001 21.5 0.2 0.00016 20.9 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 OAG04257.1 - 0.00079 20.0 0.5 0.0014 19.2 0.5 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OAG04257.1 - 0.0012 17.9 0.2 0.0017 17.4 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG04257.1 - 0.002 17.6 0.1 0.0028 17.1 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 OAG04257.1 - 0.0055 16.7 0.1 0.0093 15.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 OAG04257.1 - 0.0077 16.1 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OAG04257.1 - 0.043 13.9 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAG04257.1 - 0.059 13.2 0.3 0.092 12.6 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG04257.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 OAG04257.1 - 0.16 12.2 0.3 0.27 11.5 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 OAG04258.1 - 9e-92 308.0 0.0 1.2e-91 307.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG04258.1 - 3.8e-50 170.2 0.0 7.5e-50 169.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 OAG04258.1 - 0.00049 19.3 0.1 0.00085 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG04258.1 - 0.0011 17.7 0.1 0.0017 17.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG04258.1 - 0.0018 17.6 0.1 0.0037 16.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG04258.1 - 0.0033 16.7 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAG04258.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG04258.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG04258.1 - 0.023 14.9 0.0 0.21 11.8 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAG04258.1 - 0.2 10.6 0.0 2.1 7.4 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase HATPase_c PF02518.26 OAG04259.1 - 1.1e-20 74.2 0.0 2.5e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG04259.1 - 3.2e-19 69.2 0.1 3.7e-11 43.2 0.1 3.0 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 OAG04259.1 - 8.7e-08 32.1 0.0 2.5e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAG04259.1 - 5.3e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OAG04259.1 - 1.1e-05 25.7 0.0 7.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OAG04259.1 - 0.0014 18.9 0.0 0.0057 16.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 OAG04259.1 - 0.039 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 OAG04259.1 - 0.14 12.2 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 PAS domain GMC_oxred_C PF05199.13 OAG04260.1 - 0.063 13.8 0.0 0.085 13.4 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase HTH_Tnp_Tc3_2 PF01498.18 OAG04261.1 - 1e-08 35.3 0.8 1.9e-08 34.4 0.8 1.4 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 OAG04261.1 - 2.1e-05 24.5 0.3 0.00014 21.8 0.3 2.2 1 1 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 OAG04261.1 - 3.8e-05 23.4 1.2 0.00021 21.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 OAG04261.1 - 0.00062 20.3 0.8 0.00062 20.3 0.8 2.3 1 1 2 3 3 3 1 Homeodomain-like domain Terminase_5 PF06056.12 OAG04261.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 OAG04261.1 - 0.0081 15.9 0.3 0.019 14.8 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 OAG04261.1 - 0.017 15.2 0.8 0.049 13.8 0.8 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_8 PF02954.19 OAG04261.1 - 0.027 14.3 0.1 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family PRP9_N PF16958.5 OAG04261.1 - 0.028 14.4 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus DUF4473 PF14747.6 OAG04261.1 - 0.09 13.3 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Alpha-amylase PF00128.24 OAG04262.1 - 2.3e-25 89.9 3.0 4e-25 89.1 3.0 1.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 OAG04262.1 - 0.0044 15.3 0.1 0.51 8.5 0.0 2.3 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.10 OAG04262.1 - 0.022 14.9 0.4 0.073 13.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) MFS_1 PF07690.16 OAG04263.1 - 8.8e-17 61.1 7.6 8.8e-17 61.1 7.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04263.1 - 1.9e-10 40.3 0.0 1.9e-10 40.3 0.0 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Mito_carr PF00153.27 OAG04265.1 - 1.1e-42 143.8 10.2 3.2e-17 62.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Asp_protease_2 PF13650.6 OAG04266.1 - 2.7e-05 24.7 0.0 3e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAG04266.1 - 9.4e-05 22.9 0.0 0.0001 22.8 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 OAG04266.1 - 0.21 11.4 0.0 0.21 11.4 0.0 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease SlyX PF04102.12 OAG04268.1 - 0.025 15.2 0.9 0.037 14.7 0.9 1.2 1 0 0 1 1 1 0 SlyX DUF4939 PF16297.5 OAG04268.1 - 0.087 12.7 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-H2C2_2 PF13465.6 OAG04269.1 - 2.9e-06 27.5 14.6 2.1e-05 24.7 7.7 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG04269.1 - 8e-06 26.0 15.1 0.0012 19.2 2.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG04269.1 - 0.013 16.3 14.3 0.017 15.9 2.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DLIC PF05783.11 OAG04269.1 - 0.014 14.3 2.2 0.023 13.6 2.2 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TRAF6_Z2 PF18048.1 OAG04269.1 - 0.42 10.8 3.6 1.4 9.1 1.1 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 C1_4 PF07975.12 OAG04269.1 - 0.54 10.5 4.0 1 9.6 4.0 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain Alpha-amylase PF00128.24 OAG04271.1 - 2.2e-16 60.4 0.1 1.6e-15 57.5 0.1 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 OAG04271.1 - 1.3e-09 38.4 0.2 5.4e-09 36.4 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Glucosaminidase PF01832.20 OAG04271.1 - 0.015 15.8 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase AT_hook PF02178.19 OAG04273.1 - 0.0091 15.8 0.8 0.018 14.9 0.8 1.5 1 0 0 1 1 1 1 AT hook motif Med3 PF11593.8 OAG04273.1 - 0.035 13.3 2.4 0.034 13.3 2.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zn_clus PF00172.18 OAG04275.1 - 1.8e-05 24.7 19.3 2.7e-05 24.2 19.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tnp_zf-ribbon_2 PF13842.6 OAG04275.1 - 1.6 9.6 21.8 4.9 8.1 20.1 2.0 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Ank_4 PF13637.6 OAG04276.1 - 9.3e-14 51.6 1.6 2.2e-06 28.1 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG04276.1 - 1.4e-10 41.1 2.5 0.0028 18.0 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OAG04276.1 - 9.5e-10 38.9 0.3 1.9e-09 38.0 0.3 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG04276.1 - 6.6e-09 35.3 0.5 0.0076 16.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG04276.1 - 8e-06 26.0 0.7 0.011 16.0 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) FLgD_tudor PF13861.6 OAG04276.1 - 0.058 13.6 5.6 0.32 11.3 1.5 2.8 2 1 0 2 2 2 0 FlgD Tudor-like domain DUF1874 PF08960.10 OAG04276.1 - 0.097 12.8 0.1 7.4 6.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1874) OrsD PF12013.8 OAG04283.1 - 7.3e-12 45.7 0.8 7.8e-12 45.6 0.8 1.0 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Lys-AminoMut_A PF09043.11 OAG04283.1 - 0.06 11.8 0.0 0.07 11.6 0.0 1.0 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit AAA PF00004.29 OAG04284.1 - 0.0074 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1281_C PF18406.1 OAG04287.1 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-like domain in Api92-like protein Peptidase_M64 PF09471.10 OAG04287.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 PTR2 PF00854.21 OAG04288.1 - 1.6e-55 188.6 5.8 2.3e-55 188.1 5.8 1.2 1 0 0 1 1 1 1 POT family Abhydrolase_3 PF07859.13 OAG04289.1 - 7.4e-60 202.4 0.4 9.5e-60 202.0 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG04289.1 - 5.5e-06 26.0 0.0 0.0014 18.1 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OAG04289.1 - 0.0078 15.1 0.3 0.086 11.7 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Ank_3 PF13606.6 OAG04291.1 - 0.024 15.2 0.0 4.4 8.2 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 OAG04291.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Transp_cyt_pur PF02133.15 OAG04292.1 - 3.6e-104 349.0 42.8 4.3e-104 348.7 42.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2417 PF10329.9 OAG04292.1 - 8.8 5.7 10.5 3.3 7.1 6.9 2.1 1 1 1 2 2 2 0 Region of unknown function (DUF2417) Pro-kuma_activ PF09286.11 OAG04293.1 - 1.9e-48 164.4 0.0 3.4e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG04293.1 - 9.7e-05 21.8 0.1 0.00016 21.1 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Enterotoxin_a PF01375.17 OAG04294.1 - 7.4e-22 78.2 0.6 1e-21 77.7 0.6 1.1 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain Metaviral_G PF09595.10 OAG04294.1 - 0.17 12.0 3.4 0.24 11.5 3.4 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein FAD_binding_4 PF01565.23 OAG04295.1 - 1.3e-20 73.6 1.9 1.5e-20 73.4 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain tRNA_SAD PF07973.14 OAG04298.1 - 1e-08 35.1 0.5 2.1e-08 34.2 0.5 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OAG04298.1 - 0.00076 19.9 1.9 0.0012 19.3 1.9 1.2 1 0 0 1 1 1 1 DHHA1 domain tRNA-synt_2c PF01411.19 OAG04298.1 - 0.0016 17.1 0.0 0.0029 16.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) NUDIX PF00293.28 OAG04300.1 - 2e-14 53.8 0.0 3.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain FRB_dom PF08771.11 OAG04300.1 - 0.077 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain OAD_gamma PF04277.13 OAG04301.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SE PF08491.10 OAG04302.1 - 6.9e-99 330.3 0.0 8.5e-99 330.1 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 OAG04302.1 - 2.6e-08 33.5 0.2 9.2e-08 31.7 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG04302.1 - 1.2e-07 31.6 0.5 0.00025 20.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG04302.1 - 2.9e-05 23.6 0.3 4.5e-05 23.0 0.3 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG04302.1 - 4e-05 22.9 0.1 0.0039 16.3 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG04302.1 - 0.00018 20.5 0.6 0.24 10.2 0.1 2.4 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAG04302.1 - 0.00025 20.4 0.2 0.00048 19.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG04302.1 - 0.00049 20.3 0.9 0.00099 19.3 0.9 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG04302.1 - 0.0016 17.8 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OAG04302.1 - 0.0051 17.3 0.1 0.011 16.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG04302.1 - 0.0079 15.3 1.8 0.016 14.3 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG04302.1 - 0.016 13.9 0.3 0.029 13.1 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG04302.1 - 0.048 12.9 0.3 0.1 11.9 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OAG04302.1 - 0.048 13.3 0.2 0.091 12.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 OAG04302.1 - 0.07 12.2 1.1 0.25 10.3 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 OAG04302.1 - 0.098 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAG04302.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyoxalase PF00903.25 OAG04303.1 - 5.5e-16 58.9 0.0 2.4e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG04303.1 - 8.1e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG04303.1 - 0.11 13.3 0.0 0.8 10.5 0.0 2.2 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG04303.1 - 0.18 11.9 0.0 1.6 8.8 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase-like domain p450 PF00067.22 OAG04304.1 - 8.4e-30 103.9 0.0 1.2e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Voltage_CLC PF00654.20 OAG04305.1 - 8.4e-89 298.3 27.2 1.4e-88 297.6 27.2 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 OAG04305.1 - 1.8e-05 25.1 0.0 0.0076 16.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain ADH_N PF08240.12 OAG04306.1 - 3.6e-26 91.2 0.9 7.5e-26 90.2 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG04306.1 - 4.9e-18 65.4 1.0 1e-17 64.3 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG04306.1 - 0.00024 22.2 0.0 0.00039 21.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Lipase_3 PF01764.25 OAG04307.1 - 9.2e-20 71.0 0.0 1.8e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG04307.1 - 0.0082 16.8 0.1 0.0082 16.8 0.1 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family TGBp3 PF02495.17 OAG04307.1 - 0.2 11.3 0.1 0.74 9.5 0.0 1.9 2 0 0 2 2 2 0 Triple gene block 3 MFS_1 PF07690.16 OAG04308.1 - 1.2e-38 133.0 39.7 2.4e-38 132.0 39.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG04308.1 - 6.4e-15 54.6 18.6 8.6e-15 54.2 18.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COX7a PF02238.15 OAG04308.1 - 0.13 12.6 0.3 0.13 12.6 0.3 5.0 6 0 0 6 6 6 0 Cytochrome c oxidase subunit VII AAA_5 PF07728.14 OAG04309.1 - 1.2e-131 433.4 0.6 1.1e-22 80.5 0.0 9.6 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OAG04309.1 - 2.7e-54 181.9 9.3 4.9e-24 84.6 0.1 5.2 5 0 0 5 5 4 4 Midasin AAA lid domain AAA PF00004.29 OAG04309.1 - 5.7e-30 104.5 0.0 0.00029 21.3 0.0 7.3 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 OAG04309.1 - 1.4e-29 102.6 0.0 3.2e-10 40.0 0.0 8.2 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OAG04309.1 - 4e-28 98.2 0.1 6.3e-05 22.6 0.0 7.2 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_16 PF13191.6 OAG04309.1 - 6.4e-28 98.3 18.8 6.7e-06 26.6 0.6 9.4 7 2 0 7 7 6 6 AAA ATPase domain AAA_lid_5 PF17865.1 OAG04309.1 - 5.4e-27 94.0 0.0 2.9e-26 91.6 0.0 2.4 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_22 PF13401.6 OAG04309.1 - 3.6e-23 82.4 3.9 0.00039 20.7 0.0 8.4 7 0 0 7 7 7 4 AAA domain Dynein_heavy PF03028.15 OAG04309.1 - 5.4e-23 81.4 0.0 0.0016 18.5 0.0 7.6 8 0 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 OAG04309.1 - 8.9e-23 80.8 0.0 0.00051 19.8 0.0 6.4 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_6 PF12774.7 OAG04309.1 - 1.7e-21 76.5 0.0 0.006 15.6 0.0 8.1 8 0 0 8 8 8 5 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 OAG04309.1 - 8.4e-20 71.6 0.0 0.052 14.1 0.0 7.3 6 0 0 6 6 6 4 AAA domain Sigma54_activ_2 PF14532.6 OAG04309.1 - 3e-19 69.5 0.1 0.00023 21.3 0.0 6.7 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_33 PF13671.6 OAG04309.1 - 1.3e-17 64.2 0.3 0.16 12.1 0.0 7.7 7 1 0 7 7 6 3 AAA domain TsaE PF02367.17 OAG04309.1 - 7.8e-17 61.4 3.9 0.061 13.3 0.0 6.9 7 0 0 7 7 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OAG04309.1 - 1.3e-16 60.9 0.4 0.078 12.7 0.0 8.5 7 2 0 7 7 7 2 AAA domain AAA_14 PF13173.6 OAG04309.1 - 1e-15 57.9 0.0 0.0015 18.5 0.0 7.8 7 0 0 7 7 7 2 AAA domain T2SSE PF00437.20 OAG04309.1 - 2.2e-15 56.5 2.3 0.0024 17.0 0.0 6.6 6 0 0 6 6 6 2 Type II/IV secretion system protein Mg_chelatase PF01078.21 OAG04309.1 - 7.3e-15 54.9 0.3 0.58 9.5 0.0 9.0 9 0 0 9 9 8 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG04309.1 - 1.6e-14 54.2 0.9 0.17 12.3 0.0 6.6 6 0 0 6 6 6 3 RNA helicase NACHT PF05729.12 OAG04309.1 - 3e-13 50.0 2.0 0.16 11.8 0.0 6.6 6 0 0 6 6 6 3 NACHT domain RuvB_N PF05496.12 OAG04309.1 - 3.4e-13 49.7 0.7 0.064 13.0 0.0 6.6 7 0 0 7 7 6 3 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 OAG04309.1 - 4.1e-13 49.9 0.4 1.1 9.6 0.0 7.5 6 1 0 6 6 5 2 AAA domain ABC_tran PF00005.27 OAG04309.1 - 5.1e-11 43.2 13.2 0.053 14.0 0.0 8.5 10 0 0 10 10 6 2 ABC transporter Zeta_toxin PF06414.12 OAG04309.1 - 7.5e-11 41.7 1.6 0.77 9.0 0.0 7.1 7 0 0 7 7 6 2 Zeta toxin RsgA_GTPase PF03193.16 OAG04309.1 - 3.3e-10 40.1 0.7 1.7 8.5 0.0 6.2 6 0 0 6 6 6 2 RsgA GTPase Rad17 PF03215.15 OAG04309.1 - 8.6e-10 38.8 0.0 0.3 11.0 0.0 5.5 5 0 0 5 5 5 1 Rad17 P-loop domain IstB_IS21 PF01695.17 OAG04309.1 - 8.7e-10 38.6 0.1 2.6 7.7 0.0 6.2 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_25 PF13481.6 OAG04309.1 - 2e-09 37.3 9.0 0.21 11.2 0.1 7.2 7 0 0 7 7 7 2 AAA domain AAA_28 PF13521.6 OAG04309.1 - 2.6e-09 37.5 7.8 3.2 8.0 0.1 7.1 6 1 0 6 6 6 0 AAA domain AAA_29 PF13555.6 OAG04309.1 - 2.8e-09 36.6 2.1 3 7.6 0.0 6.7 7 0 0 7 7 6 0 P-loop containing region of AAA domain SRP54 PF00448.22 OAG04309.1 - 8.2e-08 32.1 4.0 1.7 8.2 0.0 6.0 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 OAG04309.1 - 2e-07 30.9 2.1 0.052 13.3 0.0 5.8 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 OAG04309.1 - 4.2e-07 29.7 2.7 2.1 7.9 0.0 6.1 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OAG04309.1 - 1.1e-06 28.7 0.0 4.8 7.0 0.0 5.8 6 0 0 6 6 5 0 ATPase domain predominantly from Archaea Roc PF08477.13 OAG04309.1 - 1.2e-06 28.7 0.6 3.5 7.9 0.0 5.7 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OAG04309.1 - 1.6e-06 27.6 0.3 1.9 7.9 0.0 5.5 6 0 0 6 6 4 1 Bacterial TniB protein AAA_24 PF13479.6 OAG04309.1 - 1.8e-06 27.9 3.4 5.7 6.6 0.0 6.9 7 1 0 7 7 6 0 AAA domain NTPase_1 PF03266.15 OAG04309.1 - 1.8e-06 28.0 4.0 1.7 8.5 0.1 5.8 5 0 0 5 5 5 1 NTPase MMR_HSR1 PF01926.23 OAG04309.1 - 6.2e-06 26.3 1.7 14 5.8 0.1 5.9 5 0 0 5 5 5 0 50S ribosome-binding GTPase DEAD PF00270.29 OAG04309.1 - 2e-05 24.4 0.4 15 5.3 0.0 5.8 5 1 0 5 5 4 0 DEAD/DEAH box helicase dNK PF01712.19 OAG04309.1 - 2.3e-05 24.4 2.9 3.4 7.5 0.0 5.4 6 0 0 6 6 5 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 OAG04309.1 - 2.8e-05 24.0 0.0 31 4.2 0.0 5.9 6 0 0 6 6 6 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 OAG04309.1 - 3.5e-05 23.1 0.5 5.5 6.1 0.0 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF815) PhoH PF02562.16 OAG04309.1 - 4.2e-05 23.1 0.4 14 5.0 0.0 5.6 5 0 0 5 5 5 0 PhoH-like protein SRPRB PF09439.10 OAG04309.1 - 5e-05 22.8 0.7 6.4 6.2 0.0 5.8 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit TIP49 PF06068.13 OAG04309.1 - 6e-05 22.4 1.1 0.24 10.5 0.0 5.2 6 0 0 6 6 6 1 TIP49 P-loop domain Thymidylate_kin PF02223.17 OAG04309.1 - 8.6e-05 22.3 0.9 7 6.3 0.0 5.7 6 0 0 6 6 5 0 Thymidylate kinase ResIII PF04851.15 OAG04309.1 - 9.7e-05 22.4 9.3 1.2 9.1 0.0 6.7 7 0 0 7 7 6 1 Type III restriction enzyme, res subunit MCM PF00493.23 OAG04309.1 - 0.00059 19.0 0.0 4.8 6.2 0.0 4.8 6 0 0 6 6 5 0 MCM P-loop domain ATPase PF06745.13 OAG04309.1 - 0.0009 18.6 6.6 7.9 5.8 0.0 5.9 7 0 0 7 7 5 0 KaiC ATP_bind_1 PF03029.17 OAG04309.1 - 0.00091 19.1 5.0 2.9 7.6 0.0 5.8 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 OAG04309.1 - 0.001 18.3 0.1 14 4.7 0.0 4.9 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.18 OAG04309.1 - 0.011 15.3 1.3 14 5.2 0.0 4.1 4 0 0 4 4 3 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 OAG04309.1 - 0.012 15.0 0.1 16 4.8 0.0 4.5 5 0 0 5 5 4 0 FtsK/SpoIIIE family CPT PF07931.12 OAG04309.1 - 0.013 15.4 1.3 62 3.4 0.0 5.7 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein Bac_DnaA PF00308.18 OAG04309.1 - 0.032 14.1 0.1 82 2.9 0.0 4.3 5 0 0 5 5 4 0 Bacterial dnaA protein KTI12 PF08433.10 OAG04309.1 - 0.086 12.3 0.0 48 3.3 0.0 4.4 5 0 0 5 5 3 0 Chromatin associated protein KTI12 CbiA PF01656.23 OAG04309.1 - 0.1 12.6 6.1 5.3 7.1 0.1 4.9 5 0 0 5 5 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain IPT PF01745.16 OAG04309.1 - 0.12 11.8 0.2 25 4.2 0.0 3.8 4 0 0 4 4 4 0 Isopentenyl transferase tRNA_lig_kinase PF08303.11 OAG04309.1 - 0.12 12.4 0.1 0.49 10.5 0.1 2.1 1 0 0 1 1 1 0 tRNA ligase kinase domain FAA_hydro_N_2 PF18288.1 OAG04309.1 - 0.13 12.7 4.4 30 5.1 0.0 5.1 4 0 0 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 Cytidylate_kin PF02224.18 OAG04309.1 - 0.17 11.6 2.0 39 3.9 0.0 4.8 6 0 0 6 6 3 0 Cytidylate kinase APS_kinase PF01583.20 OAG04309.1 - 0.29 11.0 1.3 7.1 6.5 0.1 3.6 5 0 0 5 5 3 0 Adenylylsulphate kinase SKI PF01202.22 OAG04309.1 - 0.34 11.0 3.3 8.3 6.5 0.0 4.1 5 0 0 5 5 3 0 Shikimate kinase MobB PF03205.14 OAG04309.1 - 1.3 9.0 6.2 96 2.9 0.0 5.5 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B DUF853 PF05872.12 OAG04309.1 - 3.6 6.1 9.8 0.53 8.8 0.0 3.3 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF853) Ribosomal_L12 PF00542.19 OAG04310.1 - 9e-21 74.0 6.5 7.8e-20 71.0 5.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OAG04310.1 - 4.8e-13 48.6 4.2 4.8e-13 48.6 4.2 3.5 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain P5CR_dimer PF14748.6 OAG04311.1 - 2e-34 118.0 1.7 2e-34 118.0 1.7 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAG04311.1 - 6.4e-08 33.1 0.4 1.8e-06 28.4 0.4 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.8 OAG04312.1 - 1.2e-43 148.0 0.0 1.7e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 OAG04312.1 - 4.8e-20 71.5 13.1 9.2e-20 70.6 13.1 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus zf-C3HC4_3 PF13920.6 OAG04313.1 - 4.1 7.4 9.3 6.4 6.7 9.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_3 PF07859.13 OAG04314.1 - 9.2e-24 84.5 0.0 1.4e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG04314.1 - 7.2e-21 74.5 0.0 8.8e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Zn_clus PF00172.18 OAG04316.1 - 7.7 6.7 13.1 60 3.9 13.1 2.4 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG04318.1 - 9.6e-34 116.6 0.0 1.3e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04318.1 - 4.9e-21 75.4 0.2 6.9e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04318.1 - 0.00012 22.1 0.1 0.00017 21.6 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG04318.1 - 0.00026 20.5 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAG04318.1 - 0.00049 20.0 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Metallophos PF00149.28 OAG04319.1 - 1.4e-12 48.6 0.0 2.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG04319.1 - 0.00022 21.5 0.1 0.00071 19.8 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Asp_protease PF09668.10 OAG04319.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Ras PF00071.22 OAG04320.1 - 4.1e-15 55.7 0.0 5.6e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG04320.1 - 0.0003 21.0 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OAG04320.1 - 0.016 15.6 0.0 0.077 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 OAG04320.1 - 0.026 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 OAG04320.1 - 0.042 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 OAG04320.1 - 0.13 12.2 0.0 0.82 9.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase PEX11 PF05648.14 OAG04324.1 - 3.7e-12 46.2 0.0 7.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1899 PF08953.11 OAG04325.1 - 9.8e-35 118.3 0.1 1.7e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OAG04325.1 - 1.3e-17 63.4 0.0 3e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OAG04325.1 - 4.8e-17 62.0 7.5 8.7e-05 23.2 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG04325.1 - 0.00028 21.1 0.1 0.23 11.8 0.1 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG04325.1 - 0.075 12.0 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SlyX PF04102.12 OAG04325.1 - 0.083 13.5 5.1 0.18 12.5 4.7 1.8 1 1 0 1 1 1 0 SlyX eIF2A PF08662.11 OAG04325.1 - 0.094 12.6 0.0 1.7 8.5 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAG04325.1 - 0.12 11.0 0.8 1.6 7.3 0.3 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PKcGMP_CC PF16808.5 OAG04325.1 - 0.14 12.1 5.5 0.36 10.7 5.5 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SSFA2_C PF14723.6 OAG04325.1 - 0.16 11.9 0.9 0.33 10.9 0.9 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus adh_short PF00106.25 OAG04328.1 - 5.1e-09 35.9 0.0 2.7e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG04328.1 - 4.5e-07 29.9 0.0 6.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 OAG04328.1 - 1.2e-05 24.6 0.0 4.3e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 OAG04328.1 - 0.00034 20.2 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG04328.1 - 0.0016 17.9 0.0 0.096 12.1 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG04328.1 - 0.0067 15.6 0.0 0.017 14.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG04328.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding EthD PF07110.11 OAG04329.1 - 0.00086 20.4 0.1 0.0011 20.0 0.1 1.3 1 1 0 1 1 1 1 EthD domain TauD PF02668.16 OAG04332.1 - 2e-57 195.1 0.4 3.2e-57 194.4 0.4 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAG04333.1 - 1.4e-18 66.9 22.7 1.4e-18 66.9 22.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 OAG04333.1 - 0.0042 15.1 0.0 0.0064 14.5 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MFS_1_like PF12832.7 OAG04333.1 - 0.023 13.6 6.5 0.041 12.8 6.5 1.4 1 0 0 1 1 1 0 MFS_1 like family Astacin PF01400.24 OAG04334.1 - 2.8e-08 33.6 0.0 0.0014 18.2 0.1 2.1 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Endonuclease_NS PF01223.23 OAG04335.1 - 1.8e-65 220.9 0.0 2.3e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease ThiF PF00899.21 OAG04336.1 - 4.1e-40 137.7 0.0 8.5e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 OAG04336.1 - 0.0035 17.6 0.4 0.04 14.2 0.4 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAG04336.1 - 0.0064 16.7 0.1 0.022 15.0 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OAG04336.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3679 PF12438.8 OAG04336.1 - 0.17 11.6 0.0 2.5 7.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3679) WD40 PF00400.32 OAG04338.1 - 1.8e-30 104.5 15.1 1.6e-09 38.2 0.3 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat NACHT PF05729.12 OAG04338.1 - 8.3e-30 103.9 0.1 1.5e-29 103.1 0.1 1.4 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 OAG04338.1 - 3.8e-12 46.3 0.5 0.021 15.1 0.1 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 OAG04338.1 - 1.8e-10 41.4 0.7 1.8e-10 41.4 0.7 3.8 3 1 1 4 4 4 2 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 OAG04338.1 - 1.8e-06 27.2 2.3 0.0062 15.5 0.9 2.8 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG04338.1 - 5.4e-05 22.0 3.9 0.33 9.5 0.2 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 CDtoxinA PF03498.14 OAG04338.1 - 0.048 13.2 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain AAA_19 PF13245.6 OAG04338.1 - 0.055 13.8 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG04338.1 - 0.12 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4411 PF14367.6 OAG04339.1 - 0.14 12.0 0.3 1.3 8.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4411) DUF3054 PF11255.8 OAG04340.1 - 0.11 13.1 4.3 0.25 11.8 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) TMEM70 PF06979.12 OAG04340.1 - 2.4 8.6 4.4 0.67 10.4 0.9 1.9 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex Peptidase_M14 PF00246.24 OAG04341.1 - 1.4e-74 251.5 0.0 1.7e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 OAG04342.1 - 2.2e-31 109.0 0.0 3.4e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAG04342.1 - 8.5e-05 23.0 0.2 0.00018 22.0 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 OAG04342.1 - 0.00011 22.5 0.3 0.00025 21.4 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain adh_short_C2 PF13561.6 OAG04343.1 - 1.8e-42 145.5 0.0 2e-41 142.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG04343.1 - 5.1e-38 130.5 0.1 2.2e-36 125.2 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG04343.1 - 2.4e-07 30.8 0.0 3.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG04343.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG04343.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 OAG04344.1 - 4.3e-08 32.4 0.0 7.2e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG04344.1 - 1.9e-07 31.1 10.1 3e-07 30.4 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 OAG04345.1 - 6.7e-17 61.7 0.0 2.6e-16 59.8 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase Tannase PF07519.11 OAG04347.1 - 4e-87 293.1 0.0 5.1e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG04347.1 - 8.7e-05 22.1 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family UPF0113_N PF17833.1 OAG04348.1 - 2.5e-26 92.0 0.0 3.4e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OAG04348.1 - 1.3e-24 86.2 0.0 2.1e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain NOC3p PF07540.11 OAG04349.1 - 1.6e-30 105.4 0.1 1.6e-30 105.4 0.1 2.8 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 OAG04349.1 - 2.7e-25 89.4 0.0 2.7e-25 89.4 0.0 2.6 2 1 0 2 2 2 1 CBF/Mak21 family POR PF01558.18 OAG04349.1 - 0.15 12.1 0.7 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase MMR_HSR1 PF01926.23 OAG04350.1 - 2e-13 50.4 0.0 3.8e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG04350.1 - 0.0023 17.5 0.2 0.0083 15.7 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG04350.1 - 0.0024 17.8 0.3 0.0073 16.2 0.3 1.9 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OAG04350.1 - 0.0031 17.6 0.2 0.36 10.9 0.1 2.4 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 OAG04350.1 - 0.0045 17.4 0.0 0.0073 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OAG04350.1 - 0.011 16.3 0.4 0.045 14.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OAG04350.1 - 0.018 14.0 0.1 0.036 13.0 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 OAG04350.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain W2 PF02020.18 OAG04350.1 - 0.1 12.8 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon AAA_28 PF13521.6 OAG04350.1 - 0.12 12.6 2.5 0.84 9.9 0.0 3.0 3 1 0 3 3 3 0 AAA domain MFS_1 PF07690.16 OAG04351.1 - 5e-13 48.7 58.9 3.7e-12 45.8 55.5 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG04351.1 - 0.00013 20.6 17.9 0.00018 20.1 17.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 OAG04351.1 - 7.5 6.8 10.8 0.11 12.6 1.5 2.8 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Peptidase_M14 PF00246.24 OAG04353.1 - 3e-14 53.5 0.0 3.1e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase ArfGap PF01412.18 OAG04355.1 - 4.4e-31 107.4 0.2 7.7e-31 106.6 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf WSC PF01822.19 OAG04356.1 - 3.5e-09 36.7 9.2 9.4e-09 35.4 9.2 1.7 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 OAG04356.1 - 5.9e-05 22.4 1.5 0.00012 21.4 1.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_HK97_TLTM PF06120.11 OAG04356.1 - 0.0032 16.7 0.1 0.0047 16.1 0.1 1.2 1 0 0 1 1 1 1 Tail length tape measure protein PTP_tm PF18861.1 OAG04356.1 - 0.023 14.7 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 OAG04356.1 - 0.065 14.1 0.0 0.54 11.2 0.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 OAG04356.1 - 0.08 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4366 PF14283.6 OAG04356.1 - 0.088 12.9 0.7 0.28 11.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) CD34_antigen PF06365.12 OAG04356.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Nitrate_red_gam PF02665.14 OAG04356.1 - 0.15 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4328 PF14219.6 OAG04356.1 - 0.25 10.9 0.9 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Beta-APP PF03494.13 OAG04356.1 - 0.28 11.1 2.1 0.37 10.7 0.9 1.8 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Pex14_N PF04695.13 OAG04356.1 - 1.3 9.6 9.6 0.12 13.0 4.9 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region adh_short_C2 PF13561.6 OAG04358.1 - 1.8e-35 122.6 4.7 1.2e-34 119.9 4.7 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG04358.1 - 2.2e-26 92.5 3.0 3.5e-26 91.9 3.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG04358.1 - 4.1e-07 30.1 1.3 4.7e-07 29.9 0.4 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG04358.1 - 0.017 14.3 0.2 0.029 13.5 0.1 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1772 PF08592.11 OAG04359.1 - 6.1e-07 29.8 0.3 7.6e-07 29.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) F-box-like PF12937.7 OAG04360.1 - 0.00031 20.6 0.0 0.001 18.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like TetR_C_37 PF18665.1 OAG04360.1 - 0.018 15.7 0.0 0.035 14.7 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 OAG04362.1 - 7.4e-31 107.3 32.6 1.3e-30 106.6 32.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HGTP_anticodon2 PF12745.7 OAG04362.1 - 0.078 12.5 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Glyco_hydro_92 PF07971.12 OAG04363.1 - 1e-144 482.9 0.1 1.2e-144 482.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG04363.1 - 1.2e-66 225.0 1.8 2.1e-66 224.2 1.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Peptidase_M13_N PF05649.13 OAG04367.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M13 E1-E2_ATPase PF00122.20 OAG04369.1 - 1.2e-37 129.2 10.4 5.4e-28 97.7 0.0 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG04369.1 - 2.9e-25 89.0 3.4 2.9e-25 89.0 3.4 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG04369.1 - 2.3e-21 77.0 0.8 7.5e-20 72.1 0.8 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG04369.1 - 1.4e-12 47.5 0.0 3.5e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG04369.1 - 3.9e-08 33.3 0.5 4.3e-07 29.9 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 OAG04369.1 - 0.011 15.6 1.2 0.026 14.4 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) tRNA-synt_1c PF00749.21 OAG04370.1 - 5.6e-107 357.3 0.0 8.4e-107 356.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAG04370.1 - 7.9e-35 120.3 0.7 1.3e-34 119.5 0.7 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 OAG04370.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG04370.1 - 0.063 13.5 0.0 1.6 9.0 0.0 2.7 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Transglut_core PF01841.19 OAG04371.1 - 8.8e-11 42.3 0.1 2.3e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 OAG04371.1 - 2.1e-06 27.3 0.2 7.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OAG04371.1 - 8.6e-05 22.1 0.1 0.00021 20.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG04371.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Ank_4 PF13637.6 OAG04373.1 - 6.9e-16 58.4 1.0 6.9e-08 32.9 0.1 5.4 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG04373.1 - 2e-15 57.1 2.3 9.4e-11 42.2 0.1 5.5 4 2 1 6 6 6 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG04373.1 - 7.5e-12 44.3 4.4 0.001 19.3 0.1 6.1 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 OAG04373.1 - 1e-07 32.0 6.9 0.004 17.5 0.4 6.0 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OAG04373.1 - 0.00091 19.5 5.1 0.2 12.0 0.4 4.7 6 1 1 7 7 7 1 Ankyrin repeats (many copies) ADH_zinc_N PF00107.26 OAG04373.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_hydro_28 PF00295.17 OAG04374.1 - 2.7e-28 99.0 10.1 3.4e-28 98.6 10.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 OAG04374.1 - 1.4e-05 25.0 12.8 3.5e-05 23.7 6.8 3.0 1 1 2 3 3 3 1 Pectate lyase superfamily protein Arylsulfotran_2 PF14269.6 OAG04375.1 - 1.2e-90 304.0 0.2 1.6e-90 303.5 0.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG04375.1 - 3e-14 52.7 1.0 4.8e-13 48.8 1.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) LapA_dom PF06305.11 OAG04376.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Lactamase_B PF00753.27 OAG04377.1 - 4.8e-07 30.0 2.9 7.3e-06 26.1 2.9 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG04377.1 - 0.00096 18.7 0.1 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_21 PF13506.6 OAG04378.1 - 2.9e-10 39.9 0.2 0.00065 19.2 0.0 3.8 3 1 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OAG04378.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 HAT_KAT11 PF08214.11 OAG04379.1 - 8.1e-97 324.6 0.0 1.2e-96 324.1 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.6 OAG04380.1 - 1.7e-26 92.9 0.0 5e-26 91.4 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG04380.1 - 2.6e-05 24.8 0.0 9.7e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Ribonuclease III domain Pyr_redox_2 PF07992.14 OAG04381.1 - 6.3e-08 32.2 0.4 0.001 18.4 0.1 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG04381.1 - 9.1e-07 28.4 0.0 3.3e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG04381.1 - 6.3e-06 24.9 0.0 3.3e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG04381.1 - 3e-05 24.2 0.0 8.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG04381.1 - 0.00073 19.6 0.1 0.031 14.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 OAG04381.1 - 0.0028 16.9 0.0 0.047 12.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAG04381.1 - 0.01 14.9 0.4 0.017 14.2 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 OAG04381.1 - 0.17 11.3 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HMGL-like PF00682.19 OAG04382.1 - 3.7e-69 233.2 0.0 5.1e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like DIOX_N PF14226.6 OAG04383.1 - 1.7e-21 77.1 0.1 3e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG04383.1 - 2.4e-09 37.6 0.0 4.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG04384.1 - 9.7e-21 74.1 68.7 7e-17 61.4 37.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG04384.1 - 0.00068 19.0 16.1 0.0012 18.2 15.4 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB LapA_dom PF06305.11 OAG04384.1 - 0.26 11.1 4.5 0.19 11.6 0.4 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Aminotran_4 PF01063.19 OAG04385.1 - 2.5e-35 122.3 0.0 3.3e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Fungal_trans PF04082.18 OAG04386.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Aconitase PF00330.20 OAG04387.1 - 1.6e-150 502.1 0.0 2.2e-150 501.7 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG04387.1 - 5.8e-30 104.3 0.0 1.3e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Acetyltransf_15 PF17013.5 OAG04387.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase AAA PF00004.29 OAG04388.1 - 8.1e-17 61.9 0.0 1.6e-16 60.9 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG04388.1 - 4.2e-07 30.0 0.3 7.7e-05 22.7 0.3 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG04388.1 - 0.00093 19.0 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG04388.1 - 0.0021 18.5 0.1 0.0032 17.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OAG04388.1 - 0.0077 16.8 0.0 0.014 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OAG04388.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 OAG04388.1 - 0.019 14.7 0.1 0.03 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG04388.1 - 0.031 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OAG04388.1 - 0.034 14.5 0.0 0.056 13.8 0.0 1.5 1 1 0 1 1 1 0 RNA helicase ATPase PF06745.13 OAG04388.1 - 0.074 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 KaiC Cytidylate_kin PF02224.18 OAG04388.1 - 0.098 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase MMR_HSR1 PF01926.23 OAG04388.1 - 0.13 12.4 0.1 0.37 10.9 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 OAG04388.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG04388.1 - 0.19 11.0 0.1 0.32 10.2 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PPV_E1_C PF00519.17 OAG04388.1 - 0.26 10.1 0.0 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DUF3433 PF11915.8 OAG04389.1 - 3.4e-30 104.3 19.9 6.2e-18 65.0 0.3 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DEAD PF00270.29 OAG04390.1 - 1.4e-16 60.8 0.0 2.6e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG04390.1 - 2.9e-12 46.9 0.0 1.1e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG04390.1 - 1.6e-06 28.4 0.0 5.5e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Esterase_phd PF10503.9 OAG04391.1 - 2e-21 76.5 0.0 2.7e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG04391.1 - 8.7e-07 28.6 0.9 1.6e-06 27.8 0.8 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OAG04391.1 - 0.0053 15.7 0.1 0.0096 14.8 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG04391.1 - 0.037 13.9 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Talin_middle PF09141.10 OAG04393.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Talin, middle domain Peptidase_S41 PF03572.18 OAG04394.1 - 2.4e-07 30.5 0.0 4.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 HET PF06985.11 OAG04395.1 - 1.8e-32 112.7 0.0 5.9e-32 111.0 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) BCS1_N PF08740.11 OAG04396.1 - 2.1e-43 148.5 1.1 3.2e-43 147.9 1.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAG04396.1 - 2.2e-17 63.7 0.0 6.8e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG04396.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG04396.1 - 0.026 14.9 0.0 0.069 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 OAG04396.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF1996 PF09362.10 OAG04397.1 - 1.3e-82 277.3 0.2 1.8e-82 276.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) LCCL PF03815.19 OAG04398.1 - 5.8e-22 77.6 0.1 1e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.21 OAG04399.1 - 6e-07 28.9 0.0 3.9e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Thymidylate_kin PF02223.17 OAG04402.1 - 8e-42 143.0 0.0 8.8e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CPT PF07931.12 OAG04402.1 - 0.0019 18.0 0.0 0.0025 17.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Resolvase PF00239.21 OAG04402.1 - 0.003 17.7 0.0 0.0045 17.1 0.0 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain AAA_33 PF13671.6 OAG04402.1 - 0.01 16.0 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 OAG04402.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.2 1 1 0 1 1 1 0 Chromatin associated protein KTI12 PPK2 PF03976.14 OAG04402.1 - 0.02 14.4 0.0 0.047 13.2 0.0 1.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) AAA_28 PF13521.6 OAG04402.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG04402.1 - 0.09 13.3 0.0 0.096 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 OAG04402.1 - 0.15 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase APS-reductase_C PF12139.8 OAG04402.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit GIY-YIG PF01541.24 OAG04403.1 - 3.6e-20 72.0 0.1 1.2e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.8 OAG04403.1 - 4.9e-05 23.4 2.7 8.9e-05 22.6 2.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 OAG04403.1 - 0.0015 18.8 2.6 0.0034 17.6 2.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 OAG04403.1 - 0.0085 16.0 3.8 0.016 15.1 3.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 OAG04403.1 - 0.017 15.3 3.4 0.033 14.4 3.4 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 OAG04403.1 - 3.9 7.6 6.4 20 5.3 1.0 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PLU-1 PF08429.11 OAG04404.1 - 5.6e-106 354.5 10.0 5.8e-104 347.9 7.3 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 OAG04404.1 - 1e-42 145.2 0.2 2e-42 144.2 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 OAG04404.1 - 3.4e-22 78.9 0.1 9.4e-22 77.5 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 OAG04404.1 - 1.6e-17 63.1 25.4 1.8e-10 40.6 4.2 3.1 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 OAG04404.1 - 2e-16 59.6 0.2 5.6e-16 58.2 0.2 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 OAG04404.1 - 2.4e-12 47.0 2.1 5.9e-12 45.8 2.1 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 OAG04404.1 - 0.018 14.7 4.7 1.5 8.4 0.7 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 OAG04404.1 - 0.059 13.3 9.4 2 8.4 5.0 3.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 OAG04404.1 - 0.19 12.0 11.5 0.055 13.7 1.5 3.3 3 0 0 3 3 3 0 PHD-like zinc-binding domain Rubredoxin PF00301.20 OAG04404.1 - 1.1 9.3 5.7 3.6 7.7 0.2 3.5 3 0 0 3 3 3 0 Rubredoxin zf-RING_9 PF13901.6 OAG04404.1 - 5.2 7.0 10.3 16 5.4 0.8 2.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-HC5HC2H_2 PF13832.6 OAG04404.1 - 8.4 6.6 9.8 0.36 11.0 1.0 2.7 3 0 0 3 3 3 0 PHD-zinc-finger like domain 60KD_IMP PF02096.20 OAG04405.1 - 1.8e-12 47.4 0.1 2.9e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein TonB_N PF16031.5 OAG04405.1 - 0.013 16.0 2.2 0.013 16.0 2.2 2.5 2 0 0 2 2 2 0 TonB polyproline region EMC3_TMCO1 PF01956.16 OAG04405.1 - 0.29 10.9 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like TOM13 PF08219.11 OAG04406.1 - 8.8e-35 118.5 0.0 1.1e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 OAG04407.1 - 5.7e-26 90.9 0.0 1.3e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OAG04407.1 - 1.1e-16 60.8 0.0 1.6e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAG04407.1 - 4.4e-11 42.4 0.1 8e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 OAG04407.1 - 0.0044 16.6 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain SurE PF01975.17 OAG04408.1 - 5.4e-24 85.1 3.3 7.2e-24 84.6 3.3 1.1 1 0 0 1 1 1 1 Survival protein SurE SBP_bac_3 PF00497.20 OAG04409.1 - 2.1e-05 24.1 0.0 4.4e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 OAG04409.1 - 2.8e-05 23.8 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 OAG04409.1 - 3e-05 24.0 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_11 PF13531.6 OAG04409.1 - 0.01 15.6 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein NMT1_3 PF16868.5 OAG04409.1 - 0.047 13.1 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family NAPRTase_N PF17767.1 OAG04409.1 - 0.067 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain FMO-like PF00743.19 OAG04410.1 - 5.3e-39 134.0 0.0 5.2e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG04410.1 - 5e-17 62.1 0.0 7.2e-11 41.9 0.1 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG04410.1 - 1.7e-11 43.9 0.2 7.1e-08 32.0 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG04410.1 - 1.4e-10 40.9 0.0 1.2e-09 37.8 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG04410.1 - 1.4e-07 31.7 0.0 3.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG04410.1 - 5.7e-07 29.7 0.1 6.4e-06 26.2 0.2 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAG04410.1 - 7.2e-07 29.1 0.0 0.0028 17.3 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG04410.1 - 2.8e-06 26.7 0.0 1.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OAG04410.1 - 0.0006 18.6 0.0 0.042 12.6 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 OAG04410.1 - 0.0074 15.8 0.0 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus MCRA PF06100.11 OAG04410.1 - 0.038 12.8 0.2 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 MCRA family Amino_oxidase PF01593.24 OAG04410.1 - 0.041 13.2 0.1 0.83 8.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAG04410.1 - 0.067 12.5 0.0 0.13 11.5 0.0 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG04410.1 - 0.11 12.6 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAG04410.1 - 0.17 12.5 0.0 1.1 9.9 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG04410.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain AMP-binding PF00501.28 OAG04411.1 - 9.4e-67 225.4 0.0 1.3e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAG04411.1 - 1.9e-09 36.8 0.0 4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 OAG04411.1 - 8.1e-07 29.9 0.1 2.5e-06 28.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 OAG04411.1 - 0.019 15.3 0.0 0.06 13.7 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Peroxidase_2 PF01328.17 OAG04412.1 - 2.7e-44 151.9 0.0 3.5e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 zf_C2H2_ZHX PF18387.1 OAG04412.1 - 0.09 12.4 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DHHA2 PF02833.14 OAG04415.1 - 1.8e-38 132.0 0.1 5.6e-38 130.3 0.1 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 OAG04415.1 - 6.3e-09 36.0 0.1 4.1e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 DHH family Cu_amine_oxid PF01179.20 OAG04417.1 - 1.8e-121 405.9 2.3 2.6e-121 405.4 0.3 1.9 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 OAG04417.1 - 9.3e-24 83.0 2.8 1.2e-23 82.6 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 OAG04417.1 - 0.002 18.3 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain GFA PF04828.14 OAG04418.1 - 1.3e-19 70.3 6.3 1.6e-10 41.2 0.0 2.9 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 OAG04418.1 - 0.0063 16.6 0.5 5.1 7.3 0.1 2.6 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.16 OAG04418.1 - 0.019 15.3 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_2 PF13240.6 OAG04418.1 - 0.088 12.6 2.3 8.5 6.2 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 OAG04418.1 - 1.5 8.8 9.2 0.94 9.5 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal PLA2_B PF01735.18 OAG04419.1 - 3e-106 355.8 0.1 3.7e-106 355.5 0.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Pkinase PF00069.25 OAG04420.1 - 1.4e-08 34.4 0.0 0.00078 18.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04420.1 - 6.9e-05 22.3 0.0 0.00035 19.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Cnd3 PF12719.7 OAG04421.1 - 5e-66 222.9 1.1 5e-66 222.9 1.1 2.8 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OAG04421.1 - 4.1e-07 30.3 0.3 4.1e-07 30.3 0.3 4.2 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 OAG04421.1 - 2.8e-05 24.0 4.7 0.43 11.0 0.1 5.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 OAG04421.1 - 0.058 13.9 5.0 1.7 9.3 0.3 5.0 4 1 1 5 5 5 0 HEAT-like repeat AROS PF15684.5 OAG04421.1 - 0.23 12.0 4.3 0.68 10.5 4.3 1.8 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 SSP160 PF06933.11 OAG04421.1 - 0.45 8.7 2.3 0.67 8.1 2.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Trp_dioxygenase PF03301.13 OAG04421.1 - 1.3 8.2 5.0 2.4 7.4 0.4 2.8 3 0 0 3 3 3 0 Tryptophan 2,3-dioxygenase PALP PF00291.25 OAG04422.1 - 1.1e-66 225.2 0.0 1.3e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NUDIX PF00293.28 OAG04423.1 - 3.6e-15 56.2 0.2 8.6e-15 54.9 0.2 1.6 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAG04423.1 - 7.5e-14 52.2 0.0 2.3e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 OAG04423.1 - 1.2e-05 24.9 1.3 2.6e-05 23.8 1.3 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain COG2 PF06148.11 OAG04424.1 - 1e-29 103.3 0.0 2e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 OAG04424.1 - 0.0026 17.8 0.1 0.0051 16.9 0.0 1.6 1 1 0 1 1 1 1 Vps51/Vps67 Ribosomal_L1 PF00687.21 OAG04425.1 - 3.1e-31 108.7 0.0 4.8e-31 108.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF5347 PF17282.2 OAG04425.1 - 0.14 12.4 0.3 0.44 10.9 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5347) ParA PF10609.9 OAG04427.1 - 1.6e-88 296.3 0.1 3.4e-60 203.6 0.0 2.0 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAG04427.1 - 2.9e-12 46.8 0.0 2e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 OAG04427.1 - 2e-08 33.9 0.0 3.5e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 OAG04427.1 - 3.1e-05 24.0 0.5 0.00012 22.1 0.4 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OAG04427.1 - 4.7e-05 22.7 3.1 5.1e-05 22.6 1.1 2.0 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 OAG04427.1 - 5.4e-05 23.1 0.4 0.027 14.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAG04427.1 - 0.0015 18.1 0.1 0.0032 17.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OAG04427.1 - 0.0019 17.3 0.1 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 OAG04427.1 - 0.0022 17.5 0.1 0.0075 15.8 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Zeta_toxin PF06414.12 OAG04427.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 OAG04427.1 - 0.03 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 OAG04427.1 - 0.064 13.2 0.8 0.14 12.0 0.8 1.5 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 OAG04427.1 - 0.082 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 OAG04427.1 - 0.14 12.6 0.6 0.28 11.5 0.6 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 OAG04427.1 - 0.14 11.8 0.3 0.84 9.2 0.2 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 OAG04427.1 - 0.23 10.6 0.1 0.35 10.0 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain SAM_decarbox PF01536.16 OAG04428.1 - 2e-132 441.5 0.0 3e-132 441.0 0.0 1.2 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase EHN PF06441.12 OAG04429.1 - 2.4e-32 111.5 0.6 5.1e-32 110.5 0.6 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG04429.1 - 5.1e-09 36.1 0.0 9.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hid1 PF12722.7 OAG04430.1 - 0 1052.7 0.0 0 1052.5 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OAG04430.1 - 9.2e-115 384.4 0.0 1.1e-114 384.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein ERCC3_RAD25_C PF16203.5 OAG04431.1 - 7.5e-112 372.5 0.1 1.4e-111 371.6 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OAG04431.1 - 1.3e-30 106.2 0.1 2.9e-30 105.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG04431.1 - 6.1e-15 55.6 0.0 1.2e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG04431.1 - 1.7e-13 50.8 0.1 4.2e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OAG04431.1 - 2.6e-05 23.1 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Zn_clus PF00172.18 OAG04432.1 - 3.6e-08 33.4 13.3 6.5e-08 32.6 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG04432.1 - 8e-07 28.4 0.4 1.4e-06 27.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.31 OAG04435.1 - 5.4e-10 39.3 0.0 1.4e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_59 PF02057.15 OAG04436.1 - 4.7e-14 52.3 0.2 9.4e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 OAG04436.1 - 1.4e-13 51.2 5.3 2.5e-13 50.4 0.4 2.3 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 OAG04436.1 - 4.9e-10 38.9 0.0 7.5e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OAG04436.1 - 7.8e-07 29.2 1.8 2.5e-06 27.6 1.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain NmrA PF05368.13 OAG04437.1 - 6.8e-13 48.7 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG04437.1 - 4.6e-05 23.4 0.1 0.00033 20.6 0.0 2.4 2 1 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG04437.1 - 0.011 16.2 0.6 0.2 12.1 0.0 2.6 3 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OAG04437.1 - 0.033 14.1 0.2 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 KR domain Hap4_Hap_bind PF10297.9 OAG04438.1 - 0.00011 22.1 3.3 0.00028 20.9 3.3 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 OAG04438.1 - 0.021 14.9 16.4 0.038 14.1 14.3 2.5 1 1 1 2 2 2 0 bZIP transcription factor IFT57 PF10498.9 OAG04438.1 - 0.72 8.8 9.7 1.3 7.9 9.7 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 UPF0242 PF06785.11 OAG04438.1 - 0.74 9.9 12.1 1.2 9.2 12.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 OAG04438.1 - 2.2 7.5 6.1 3.1 7.0 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 OAG04438.1 - 2.3 6.7 5.7 3.3 6.2 5.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TEX13 PF15186.6 OAG04438.1 - 5 6.8 10.2 9.4 5.9 10.2 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF4360 PF14273.6 OAG04440.1 - 0.00053 19.9 0.1 0.0062 16.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) SPX PF03105.19 OAG04441.1 - 3.1e-75 254.5 2.8 3.1e-75 254.5 2.8 2.2 2 0 0 2 2 2 1 SPX domain EXS PF03124.14 OAG04441.1 - 2.7e-71 240.6 14.1 4.4e-71 239.9 14.1 1.3 1 0 0 1 1 1 1 EXS family adh_short PF00106.25 OAG04441.1 - 3e-35 121.4 0.1 4.9e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04441.1 - 5.7e-22 78.4 0.1 1.5e-21 77.1 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04441.1 - 6.7e-09 35.9 0.0 1.7e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG04441.1 - 0.004 16.3 0.1 0.007 15.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ribosom_S30AE_C PF16321.5 OAG04441.1 - 0.0089 15.7 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus TrkA_N PF02254.18 OAG04441.1 - 0.023 14.9 0.1 0.047 14.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 OAG04441.1 - 0.03 13.8 0.1 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 OAG04441.1 - 0.075 12.9 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Cwf_Cwc_15 PF04889.12 OAG04441.1 - 0.3 10.8 13.8 0.056 13.2 4.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mif2_N PF15624.6 OAG04441.1 - 1.4 9.7 9.9 0.3 11.8 1.6 2.8 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Abhydrolase_2 PF02230.16 OAG04442.1 - 2.9e-23 82.8 0.0 3.6e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAG04442.1 - 4.4e-08 34.0 0.0 5.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAG04442.1 - 0.0029 17.2 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAG04442.1 - 0.011 15.0 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG04442.1 - 0.015 14.9 0.7 0.1 12.2 0.7 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 OAG04442.1 - 0.072 12.9 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF3759 PF12585.8 OAG04443.1 - 7.6e-41 138.1 7.2 1.1e-40 137.6 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 OAG04443.1 - 2.3 8.9 8.4 17 6.0 7.3 2.3 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) PAF-AH_p_II PF03403.13 OAG04444.1 - 6.8e-07 28.1 0.0 0.0003 19.4 0.0 2.4 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAG04444.1 - 2.5e-06 26.9 0.0 0.0062 15.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG04444.1 - 3.4e-05 24.6 3.7 3.4e-05 24.6 3.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG04444.1 - 0.00018 21.2 0.1 0.0083 15.8 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 OAG04444.1 - 0.052 13.3 0.1 5 6.9 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OAG04444.1 - 0.23 10.4 0.1 0.46 9.3 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme 7tm_7 PF08395.12 OAG04445.1 - 0.0018 17.6 1.1 0.0032 16.7 1.1 1.3 1 0 0 1 1 1 1 7tm Chemosensory receptor SUR7 PF06687.12 OAG04445.1 - 0.88 9.2 4.5 1.6 8.3 2.3 2.0 2 0 0 2 2 2 0 SUR7/PalI family Syntaxin-6_N PF09177.11 OAG04446.1 - 8.3e-27 93.6 2.5 1.2e-26 93.2 0.3 2.1 3 0 0 3 3 2 1 Syntaxin 6, N-terminal Prominin PF05478.11 OAG04446.1 - 0.00044 18.4 0.4 0.1 10.5 0.0 2.0 2 0 0 2 2 2 2 Prominin SNARE PF05739.19 OAG04446.1 - 0.0027 17.7 1.5 0.0027 17.7 1.5 2.2 3 0 0 3 3 1 1 SNARE domain RRF PF01765.19 OAG04446.1 - 0.0046 16.9 6.0 1 9.3 0.2 2.9 1 1 2 3 3 3 2 Ribosome recycling factor DUF4795 PF16043.5 OAG04446.1 - 0.0066 16.1 0.8 0.0066 16.1 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) HMMR_N PF15905.5 OAG04446.1 - 0.0071 15.9 1.4 0.0071 15.9 1.4 2.0 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Mer2 PF09074.10 OAG04446.1 - 0.014 15.2 2.6 0.022 14.5 1.8 1.7 1 1 1 2 2 2 0 Mer2 DUF4618 PF15397.6 OAG04446.1 - 0.015 14.8 1.4 0.91 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) WXG100 PF06013.12 OAG04446.1 - 0.016 15.5 5.3 5 7.4 0.1 3.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Syntaxin_2 PF14523.6 OAG04446.1 - 0.021 15.2 1.7 0.044 14.1 0.4 2.0 2 0 0 2 2 2 0 Syntaxin-like protein DUF2207 PF09972.9 OAG04446.1 - 0.023 13.5 0.1 0.061 12.1 0.0 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF883 PF05957.13 OAG04446.1 - 0.023 15.3 7.8 0.51 11.0 0.2 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) APG6_N PF17675.1 OAG04446.1 - 0.024 15.2 1.4 0.024 15.2 1.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region KxDL PF10241.9 OAG04446.1 - 0.039 14.2 2.2 3.1 8.2 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF2205 PF10224.9 OAG04446.1 - 0.048 13.6 0.8 0.048 13.6 0.8 2.8 2 2 1 3 3 3 0 Short coiled-coil protein OmpH PF03938.14 OAG04446.1 - 0.052 13.9 11.1 20 5.5 11.1 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 OAG04446.1 - 0.056 12.3 7.2 0.037 12.9 1.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 OAG04446.1 - 0.073 11.9 8.0 0.17 10.8 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Baculo_F PF12259.8 OAG04446.1 - 0.09 11.3 0.6 0.17 10.4 0.2 1.6 2 0 0 2 2 2 0 Baculovirus F protein DUF1664 PF07889.12 OAG04446.1 - 0.096 12.7 7.0 0.63 10.1 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 OAG04446.1 - 0.1 11.2 0.4 0.22 10.1 0.1 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A YtxH PF12732.7 OAG04446.1 - 0.1 13.1 3.6 20 5.8 3.6 3.0 1 1 0 1 1 1 0 YtxH-like protein ApoLp-III PF07464.11 OAG04446.1 - 0.11 12.6 4.0 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Cluap1 PF10234.9 OAG04446.1 - 0.11 11.9 5.1 1.6 8.1 0.4 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 Atg14 PF10186.9 OAG04446.1 - 0.11 11.6 0.2 0.19 10.8 0.2 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 OAG04446.1 - 0.13 12.3 1.9 1.2 9.2 0.5 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DotU PF09850.9 OAG04446.1 - 0.14 11.8 6.2 0.56 9.9 0.3 3.1 2 2 1 3 3 3 0 Type VI secretion system protein DotU DUF4164 PF13747.6 OAG04446.1 - 0.15 12.4 9.5 4.6 7.6 3.6 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Fez1 PF06818.15 OAG04446.1 - 0.17 12.3 4.7 0.26 11.7 4.7 1.3 1 0 0 1 1 1 0 Fez1 DUF5089 PF17002.5 OAG04446.1 - 0.23 11.3 2.8 0.77 9.6 2.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) T3SS_needle_F PF09392.10 OAG04446.1 - 0.27 11.4 2.6 14 6.0 0.1 3.2 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF3618 PF12277.8 OAG04446.1 - 0.28 11.5 8.1 7 7.0 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) GCIP PF13324.6 OAG04446.1 - 0.32 10.6 8.0 2.3 7.7 4.1 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Laminin_II PF06009.12 OAG04446.1 - 0.35 10.9 4.6 8 6.5 1.2 2.6 2 1 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 OAG04446.1 - 0.58 10.7 7.5 4.9 7.7 0.2 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 OAG04446.1 - 0.58 10.9 6.1 5.6 7.7 0.1 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 OAG04446.1 - 0.66 10.6 5.0 0.85 10.3 0.8 2.3 2 0 0 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 OAG04446.1 - 0.89 9.6 6.9 1.1 9.3 0.3 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 OAG04446.1 - 1 9.1 5.5 0.38 10.5 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) MnmE_helical PF12631.7 OAG04446.1 - 1.4 9.1 6.2 2.2 8.4 6.2 1.3 1 1 0 1 1 1 0 MnmE helical domain UPF0449 PF15136.6 OAG04446.1 - 1.5 9.4 5.0 2 8.9 0.1 2.9 2 1 0 3 3 3 0 Uncharacterised protein family UPF0449 UPF0242 PF06785.11 OAG04446.1 - 1.6 8.8 12.5 0.27 11.3 0.9 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FlgN PF05130.12 OAG04446.1 - 1.9 9.0 6.8 1.5 9.3 0.5 2.7 1 1 1 3 3 3 0 FlgN protein DegS PF05384.11 OAG04446.1 - 2.2 7.7 8.3 2.7 7.5 0.2 3.0 3 0 0 3 3 3 0 Sensor protein DegS GAS PF13851.6 OAG04446.1 - 2.3 7.5 8.1 0.6 9.4 2.0 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lipoprotein_20 PF13942.6 OAG04446.1 - 2.5 8.0 6.7 3.6 7.5 0.2 2.5 3 0 0 3 3 2 0 YfhG lipoprotein Fzo_mitofusin PF04799.13 OAG04446.1 - 3.3 7.2 4.7 24 4.4 0.4 2.7 1 1 1 2 2 2 0 fzo-like conserved region KfrA_N PF11740.8 OAG04446.1 - 4.1 8.1 11.6 0.5 11.0 0.6 2.9 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Methyltransf_32 PF13679.6 OAG04447.1 - 7.7e-22 78.0 4.0 3.7e-21 75.8 4.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Antigen_Bd37 PF11641.8 OAG04447.1 - 0.049 13.1 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Glyco_hydro_72 PF03198.14 OAG04448.1 - 1.7e-115 385.6 1.2 2.2e-115 385.3 1.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 OAG04448.1 - 3.1e-05 23.3 0.0 4.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Asp PF00026.23 OAG04449.1 - 1.6e-05 24.5 0.0 2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 OAG04449.1 - 3.3e-05 23.7 0.0 0.00028 20.7 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SGS PF05002.15 OAG04450.1 - 9.2e-29 99.4 1.0 2.8e-28 97.9 1.0 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.16 OAG04450.1 - 7.7e-15 55.7 0.0 1.3e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 OAG04450.1 - 1.2e-08 34.4 7.7 0.0047 16.9 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG04450.1 - 1.5e-08 34.1 5.1 0.00042 20.0 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG04450.1 - 0.00098 19.7 9.2 0.0012 19.4 5.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG04450.1 - 0.0025 17.5 1.9 0.0025 17.5 1.9 2.4 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 OAG04450.1 - 0.0036 17.8 1.0 0.095 13.2 0.2 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG04450.1 - 0.026 14.8 7.8 0.097 13.0 2.8 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG04450.1 - 0.056 14.3 3.9 0.25 12.3 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG04450.1 - 0.063 13.5 4.7 13 6.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG04450.1 - 0.12 12.8 1.4 0.95 10.0 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG04450.1 - 0.27 11.4 2.2 0.88 9.8 0.7 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat CCDC53 PF10152.9 OAG04450.1 - 0.29 11.6 3.6 0.18 12.2 0.8 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TPR_7 PF13176.6 OAG04450.1 - 0.3 11.2 1.5 3.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG04450.1 - 0.57 10.9 2.9 27 5.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Questin_oxidase PF14027.6 OAG04451.1 - 1e-101 340.9 2.6 1.3e-101 340.6 2.6 1.1 1 0 0 1 1 1 1 Questin oxidase-like Aldo_ket_red PF00248.21 OAG04452.1 - 4e-51 174.0 0.0 4.6e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.27 OAG04453.1 - 1.8e-15 56.6 0.4 0.00044 20.1 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein Rrp15p PF07890.12 OAG04454.1 - 2.4e-38 131.5 12.2 2.4e-38 131.5 12.2 2.3 2 1 0 2 2 2 1 Rrp15p PRAS PF15798.5 OAG04454.1 - 0.43 11.2 10.9 4 8.0 4.8 2.5 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 SRP54 PF00448.22 OAG04455.1 - 3.3e-76 255.3 0.1 7.5e-76 254.1 0.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OAG04455.1 - 1.4e-29 102.6 5.5 1.4e-29 102.6 5.5 4.2 3 1 1 5 5 2 1 Signal peptide binding domain SRP54_N PF02881.19 OAG04455.1 - 7.6e-21 74.1 0.5 2.3e-20 72.6 0.5 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 OAG04455.1 - 7.1e-06 26.2 0.0 2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 OAG04455.1 - 3e-05 23.7 0.9 0.00036 20.2 0.8 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 OAG04455.1 - 7.9e-05 23.1 0.0 0.00031 21.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG04455.1 - 0.0011 19.4 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG04455.1 - 0.0012 19.1 0.1 0.0034 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 OAG04455.1 - 0.002 17.6 0.2 4.5 6.7 0.0 3.2 4 0 0 4 4 4 2 Signal recognition particle receptor beta subunit CbiA PF01656.23 OAG04455.1 - 0.007 16.4 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 OAG04455.1 - 0.0071 16.1 0.0 0.023 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAG04455.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 OAG04455.1 - 0.01 15.5 0.1 0.065 12.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase APS_kinase PF01583.20 OAG04455.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF3052 PF11253.8 OAG04455.1 - 0.016 15.2 0.1 0.055 13.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) MobB PF03205.14 OAG04455.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 OAG04455.1 - 0.028 14.2 0.4 0.099 12.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAG04455.1 - 0.066 13.3 0.3 0.26 11.4 0.1 2.2 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 OAG04455.1 - 0.067 13.7 0.0 0.17 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 OAG04455.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 OAG04455.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain cEGF PF12662.7 OAG04456.1 - 0.0067 16.3 0.4 0.017 15.0 0.4 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF PF00008.27 OAG04456.1 - 0.084 13.2 6.3 0.3 11.4 6.3 2.0 1 0 0 1 1 1 0 EGF-like domain FXa_inhibition PF14670.6 OAG04456.1 - 0.56 10.5 5.6 0.15 12.3 2.2 1.8 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Phytase PF02333.15 OAG04457.1 - 4.9e-70 236.4 0.1 3.1e-67 227.2 0.2 2.1 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 OAG04457.1 - 0.0016 18.8 13.0 0.0016 18.8 13.0 3.3 3 0 0 3 3 3 2 EGF-like domain DUF1996 PF09362.10 OAG04458.1 - 7.9e-82 274.8 0.6 1e-81 274.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Tannase PF07519.11 OAG04459.1 - 4.7e-79 266.5 2.1 1.5e-78 264.8 2.1 1.6 1 1 0 1 1 1 1 Tannase and feruloyl esterase UQ_con PF00179.26 OAG04461.1 - 5e-52 175.3 0.0 5.6e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG04461.1 - 0.082 12.6 0.0 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Scramblase PF03803.15 OAG04462.1 - 1.4e-53 181.4 0.0 3.2e-30 105.1 0.0 2.1 1 1 1 2 2 2 2 Scramblase tRNA_int_endo PF01974.17 OAG04463.1 - 1.9e-19 69.5 0.7 4.5e-18 65.1 0.7 2.4 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OAG04463.1 - 4.8e-06 26.2 0.0 0.00013 21.6 0.1 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Oxidored_molyb PF00174.19 OAG04466.1 - 3.9e-58 195.9 0.0 5.7e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG04466.1 - 2.1e-23 82.9 0.0 4.3e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 OAG04466.1 - 0.042 13.8 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 BNR/Asp-box repeat POT1 PF02765.17 OAG04467.1 - 8e-07 29.0 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 RelA_SpoT PF04607.17 OAG04469.1 - 1.1e-13 51.4 3.4 9.1e-13 48.5 3.4 2.1 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins CorA PF01544.18 OAG04470.1 - 1.3e-16 60.8 0.5 2e-16 60.2 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 OAG04470.1 - 0.045 12.5 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NDK PF00334.19 OAG04473.1 - 1.3e-54 183.8 0.0 1.5e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 OAG04474.1 - 8.6e-142 473.4 5.3 1.3e-141 472.8 5.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG04474.1 - 2.2e-25 88.8 0.7 1.2e-24 86.3 0.2 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OAG04474.1 - 2.9e-06 27.4 0.0 7.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Sugar_tr PF00083.24 OAG04475.1 - 4.4e-71 240.1 18.4 5.1e-71 239.9 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG04475.1 - 1.5e-26 93.2 24.3 1.5e-26 93.2 24.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG04475.1 - 1.2e-05 24.1 6.4 1.2e-05 24.1 6.4 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.13 OAG04475.1 - 0.0029 16.1 4.5 0.0045 15.5 4.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5345 PF17280.2 OAG04475.1 - 2.5 8.2 5.7 0.42 10.6 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF1485 PF07364.12 OAG04476.1 - 4e-109 364.3 0.1 5.2e-109 364.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 OAG04476.1 - 3.1e-61 206.7 0.1 4.7e-61 206.0 0.1 1.3 1 0 0 1 1 1 1 MlrC C-terminus GST_N_3 PF13417.6 OAG04477.1 - 1.8e-21 76.3 0.4 6.6e-10 39.3 0.1 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG04477.1 - 7.6e-14 51.8 0.1 1.3e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG04477.1 - 4.7e-11 42.5 0.6 1.8e-06 27.9 0.1 2.6 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG04477.1 - 0.00038 20.6 0.1 0.035 14.3 0.0 3.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG04477.1 - 0.0016 18.7 0.0 0.65 10.4 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GMC_oxred_N PF00732.19 OAG04478.1 - 5.3e-51 173.8 0.3 2.4e-49 168.3 0.3 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG04478.1 - 9e-31 107.3 0.0 1.7e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG04478.1 - 6.8e-05 23.0 0.1 0.00081 19.6 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG04478.1 - 0.00023 20.5 0.1 0.00039 19.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAG04478.1 - 0.0031 16.6 0.1 0.0045 16.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG04478.1 - 0.0048 16.0 0.3 0.069 12.2 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG04478.1 - 0.0051 16.4 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG04478.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zip PF02535.22 OAG04479.1 - 2.3e-49 168.5 0.3 3e-49 168.1 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SnoaL_2 PF12680.7 OAG04480.1 - 1.7e-10 41.4 0.3 2.2e-10 41.1 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG04480.1 - 8.6e-05 22.3 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 OAG04480.1 - 0.041 14.3 0.2 0.068 13.6 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) HpcH_HpaI PF03328.14 OAG04481.1 - 2.1e-33 115.3 0.0 2.7e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family FMN_dh PF01070.18 OAG04482.1 - 5e-115 384.2 0.0 6.1e-115 384.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG04482.1 - 2.6e-19 69.1 0.0 5.9e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG04482.1 - 3.2e-07 29.8 0.0 5.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG04482.1 - 1.5e-06 27.5 4.0 0.00036 19.7 1.6 2.6 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG04482.1 - 3.7e-05 23.3 0.1 0.00013 21.5 0.1 1.8 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 OAG04482.1 - 0.00062 19.3 0.2 0.17 11.3 0.0 2.8 3 0 0 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 OAG04482.1 - 0.00076 18.9 0.1 0.38 10.0 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAG04482.1 - 0.0013 17.9 0.3 0.041 13.0 0.0 2.6 2 1 1 3 3 3 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 OAG04482.1 - 0.0066 15.7 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase MIP PF00230.20 OAG04483.1 - 5.9e-48 163.5 14.8 8e-48 163.1 14.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein ETRAMP PF09716.10 OAG04483.1 - 1.4 9.0 3.3 3 8.0 0.1 2.8 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Cellulase PF00150.18 OAG04484.1 - 9e-16 58.1 4.3 2.1e-15 56.9 4.3 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.7 OAG04485.1 - 4.8e-05 23.2 0.1 0.00023 21.0 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG04485.1 - 0.0042 16.9 0.6 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 F-box domain DUF1871 PF08958.10 OAG04485.1 - 0.091 13.1 0.1 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) Glyco_hydro_47 PF01532.20 OAG04486.1 - 2.4e-178 593.7 0.0 2.8e-178 593.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Med20 PF08612.11 OAG04487.1 - 7.9e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex FAD_binding_4 PF01565.23 OAG04488.1 - 7.8e-19 67.8 0.3 1.5e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG04488.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Cellulase PF00150.18 OAG04489.1 - 1.5e-45 155.8 0.0 1.9e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 OAG04490.1 - 5.8e-39 131.7 0.0 3.5e-12 46.0 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG04490.1 - 2e-13 50.0 0.0 0.0054 16.6 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 OAG04490.1 - 7.7e-09 35.1 5.6 7.7e-09 35.1 5.6 3.9 3 1 0 3 3 3 1 Putative RRM domain DUF4523 PF15023.6 OAG04490.1 - 2.2e-05 24.3 0.0 0.096 12.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 OAG04490.1 - 0.00016 21.7 0.0 0.21 11.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 OAG04490.1 - 0.013 15.6 5.9 0.37 10.9 0.1 3.3 4 0 0 4 4 4 0 RNA binding motif RRM_Rrp7 PF17799.1 OAG04490.1 - 0.061 13.1 0.0 1.4 8.7 0.0 2.9 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 OAG04490.1 - 0.19 11.8 0.2 1.2 9.2 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain Alg6_Alg8 PF03155.15 OAG04491.1 - 1.7e-172 574.8 31.6 2.2e-172 574.4 31.6 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 OAG04491.1 - 9e-36 122.4 4.1 3.8e-35 120.4 0.5 2.8 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 OAG04491.1 - 6.7e-20 71.4 0.0 6.7e-20 71.4 0.0 2.8 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OAG04491.1 - 3e-12 46.7 0.0 7.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 DDT domain Hydrolase_like PF13242.6 OAG04491.1 - 0.18 11.9 0.0 0.49 10.5 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like MutS_III PF05192.18 OAG04491.1 - 0.61 10.3 4.1 2 8.6 4.1 1.9 1 0 0 1 1 1 0 MutS domain III SCA7 PF08313.12 OAG04492.1 - 2.9e-30 104.0 0.1 2.9e-30 104.0 0.1 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain CDC45 PF02724.14 OAG04492.1 - 0.66 8.2 3.1 0.86 7.8 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 OAG04492.1 - 2.1 8.4 6.4 9 6.4 3.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CAF1 PF04857.20 OAG04493.1 - 6.9e-75 252.2 0.0 8.4e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Pex26 PF07163.12 OAG04494.1 - 0.083 12.2 1.9 0.19 11.0 1.9 1.6 1 0 0 1 1 1 0 Pex26 protein CDC45 PF02724.14 OAG04494.1 - 0.22 9.7 7.8 0.3 9.3 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 OAG04494.1 - 0.29 9.6 7.3 0.39 9.1 7.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Hid1 PF12722.7 OAG04494.1 - 8.7 4.3 7.6 13 3.7 7.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein COesterase PF00135.28 OAG04495.1 - 1.8e-80 271.3 0.0 2.2e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG04495.1 - 1.3e-07 31.7 0.0 3e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG04495.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family HAD_2 PF13419.6 OAG04496.1 - 4.4e-09 36.7 0.0 2.6e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG04496.1 - 3.3e-05 24.3 0.0 0.003 17.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 OAG04497.1 - 3.4e-20 72.3 0.0 3e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04497.1 - 3.2e-12 46.5 0.0 1.4e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04497.1 - 3.4e-07 30.3 0.0 6.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG04497.1 - 0.00059 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 OAG04497.1 - 0.14 12.9 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_tran_WecB PF03808.13 OAG04497.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family VIT_2 PF13757.6 OAG04498.1 - 0.035 14.0 0.1 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain AA_permease PF00324.21 OAG04499.1 - 1.1e-120 403.5 42.8 1.2e-120 403.4 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG04499.1 - 2.8e-38 131.9 49.4 3.3e-38 131.6 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease TAL_FSA PF00923.19 OAG04501.1 - 4.9e-31 108.1 0.0 1.7e-30 106.4 0.0 1.8 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CoA_transf_3 PF02515.17 OAG04502.1 - 6.1e-49 167.1 0.0 7.6e-47 160.2 0.0 2.4 2 1 0 2 2 2 2 CoA-transferase family III Kelch_6 PF13964.6 OAG04503.1 - 4e-12 45.9 0.7 0.012 15.8 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OAG04503.1 - 8.3e-12 44.8 3.1 0.012 15.5 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OAG04503.1 - 8.7e-12 45.0 14.2 2.2e-06 27.8 0.0 5.4 6 1 1 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG04503.1 - 6.2e-11 42.1 6.8 0.00036 20.5 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OAG04503.1 - 1.2e-06 28.0 2.2 0.00097 18.7 0.1 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OAG04503.1 - 1.3e-05 24.9 1.6 0.56 10.3 0.1 4.0 4 0 0 4 4 4 3 Kelch motif UCH PF00443.29 OAG04504.1 - 3e-65 220.3 0.1 4.4e-65 219.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OAG04504.1 - 1.6e-14 54.3 0.0 4.1e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 OAG04504.1 - 1.8e-10 41.0 0.1 0.0015 18.2 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OAG04504.1 - 0.0099 15.6 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal ubiquitin PF00240.23 OAG04504.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Lipase_GDSL_2 PF13472.6 OAG04505.1 - 1.1e-25 91.0 0.0 3.2e-25 89.6 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG04505.1 - 8e-21 74.9 0.0 1.1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Voltage_CLC PF00654.20 OAG04506.1 - 2.5e-88 296.7 28.6 8.2e-88 295.0 23.5 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel DGF-1_C PF11040.8 OAG04506.1 - 1.2 9.2 4.1 2.5 8.2 2.8 2.2 2 1 1 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SKG6 PF08693.10 OAG04508.1 - 0.024 14.0 0.4 0.044 13.2 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 OAG04508.1 - 0.067 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FixQ PF05545.11 OAG04508.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Myb_DNA-binding PF00249.31 OAG04509.1 - 6.2e-07 29.5 0.0 0.14 12.4 0.0 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG04509.1 - 3e-06 27.0 0.1 0.004 17.0 0.0 3.2 2 1 1 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OAG04509.1 - 0.13 12.5 0.3 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain Abhydrolase_6 PF12697.7 OAG04510.1 - 1.1e-10 42.6 0.8 1.4e-10 42.2 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG04510.1 - 0.0054 16.0 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Tnp_22_dsRBD PF17490.2 OAG04510.1 - 0.09 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain DUF1996 PF09362.10 OAG04515.1 - 5.7e-17 62.5 1.3 7.5e-17 62.1 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SLAC1 PF03595.17 OAG04516.1 - 7.6e-72 242.3 44.0 8.6e-72 242.1 44.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel COPI_assoc PF08507.10 OAG04516.1 - 0.021 14.9 1.2 0.021 14.9 1.2 2.8 3 0 0 3 3 3 0 COPI associated protein zf-C3HC4_3 PF13920.6 OAG04518.1 - 1.1e-07 31.6 6.9 1.8e-07 30.9 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 OAG04518.1 - 8.1e-07 28.8 3.2 1.5e-06 27.9 3.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.25 OAG04518.1 - 1.8e-06 27.7 11.0 3.1e-06 26.9 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG04518.1 - 2.3e-06 27.5 9.5 4.6e-06 26.5 9.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG04518.1 - 3.7e-06 26.7 9.1 6.9e-06 25.8 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 OAG04518.1 - 1.1e-05 25.4 4.7 1.1e-05 25.4 4.7 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 OAG04518.1 - 3.1e-05 23.8 9.4 5.4e-05 23.1 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG04518.1 - 8.1e-05 22.9 8.3 0.00014 22.1 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 OAG04518.1 - 0.00093 19.2 6.4 0.0019 18.2 6.4 1.6 1 0 0 1 1 1 1 Zinc finger domain Prok-RING_4 PF14447.6 OAG04518.1 - 0.0032 17.3 6.2 0.0058 16.5 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG04518.1 - 0.044 13.9 8.9 0.11 12.7 8.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 OAG04518.1 - 0.045 13.6 2.8 0.045 13.6 2.8 1.7 2 0 0 2 2 1 0 CCCH-type zinc finger zf-Nse PF11789.8 OAG04518.1 - 0.096 12.5 2.5 0.17 11.8 2.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.6 OAG04518.1 - 0.098 13.2 2.8 0.23 12.0 2.8 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 OAG04518.1 - 0.29 11.4 4.9 0.67 10.3 4.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Mcp5_PH PF12814.7 OAG04519.1 - 2.2e-44 150.4 0.3 3.9e-44 149.7 0.3 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 OAG04519.1 - 0.00037 21.0 0.0 0.001 19.6 0.0 1.7 1 0 0 1 1 1 1 PH domain HIP1_clath_bdg PF16515.5 OAG04519.1 - 1.1 9.9 32.7 1.8 9.2 0.6 4.6 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Isy1 PF06246.12 OAG04520.1 - 4.7e-90 301.6 0.2 5.6e-90 301.4 0.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Cpn60_TCP1 PF00118.24 OAG04522.1 - 8.2e-151 503.0 10.6 9.3e-151 502.8 10.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 OAG04522.1 - 0.0068 16.7 0.0 0.032 14.5 0.0 2.1 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor PrpR_N PF06506.11 OAG04522.1 - 0.0084 15.7 1.6 0.022 14.3 0.1 2.3 3 0 0 3 3 3 1 Propionate catabolism activator TetR_C_14 PF17754.1 OAG04522.1 - 0.093 12.7 0.5 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 MftR C-terminal domain MRP-L46 PF11788.8 OAG04523.1 - 2.9e-36 124.8 0.3 2.9e-36 124.8 0.3 1.8 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Pantoate_transf PF02548.15 OAG04523.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Myb_DNA-bind_3 PF12776.7 OAG04524.1 - 9.7e-12 45.7 0.7 4.4e-11 43.6 0.2 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAG04524.1 - 0.00033 21.0 1.2 0.00053 20.3 0.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Glyco_hydro_3 PF00933.21 OAG04524.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Peptidase_M43 PF05572.13 OAG04525.1 - 6.1e-19 68.4 0.1 8e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OAG04525.1 - 1.1e-05 25.7 0.9 1.2e-05 25.6 0.9 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAG04525.1 - 3.6e-05 23.8 0.3 6.8e-05 22.8 0.3 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAG04525.1 - 7.4e-05 22.5 0.1 8.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OAG04525.1 - 0.0043 17.5 0.0 0.0058 17.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 OAG04525.1 - 0.016 13.8 0.4 0.017 13.7 0.4 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 OAG04525.1 - 0.025 13.6 0.3 0.035 13.0 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 OAG04525.1 - 0.19 10.9 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 OAG04525.1 - 0.22 11.4 0.4 0.34 10.8 0.4 1.2 1 0 0 1 1 1 0 Matrixin DUF5351 PF17302.2 OAG04526.1 - 0.032 14.4 0.2 0.048 13.9 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5351) Amb_V_allergen PF03913.13 OAG04526.1 - 0.072 13.0 0.6 0.1 12.6 0.6 1.2 1 0 0 1 1 1 0 Amb V Allergen Solute_trans_a PF03619.16 OAG04527.1 - 3.3e-92 308.8 16.8 3.9e-92 308.5 16.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Voltage_CLC PF00654.20 OAG04527.1 - 0.19 10.9 2.2 0.31 10.3 2.2 1.5 1 1 0 1 1 1 0 Voltage gated chloride channel SUR7 PF06687.12 OAG04527.1 - 0.9 9.1 8.9 1.6 8.3 2.4 2.3 2 0 0 2 2 2 0 SUR7/PalI family SAP PF02037.27 OAG04528.1 - 3.4e-07 29.8 0.1 6.3e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 OAG04528.1 - 4.5e-07 30.1 0.0 4.5e-07 30.1 0.0 3.3 2 1 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Pkinase PF00069.25 OAG04529.1 - 1.5e-40 139.3 0.0 4.1e-40 137.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04529.1 - 2.6e-24 85.9 0.0 3.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG04529.1 - 0.009 14.8 0.1 0.014 14.2 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase DUF1640 PF07798.11 OAG04530.1 - 0.026 14.6 3.8 0.054 13.5 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) HSBP1 PF06825.12 OAG04530.1 - 0.052 13.4 0.3 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 XhlA PF10779.9 OAG04530.1 - 0.49 10.6 1.8 1.7 8.9 0.4 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Ras PF00071.22 OAG04531.1 - 6.1e-53 178.7 0.0 7.4e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG04531.1 - 5.8e-19 68.5 0.0 8.2e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG04531.1 - 2.5e-07 30.3 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG04531.1 - 0.17 11.4 0.1 0.87 9.1 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Zn_clus PF00172.18 OAG04532.1 - 4.2e-05 23.6 12.6 0.00011 22.2 12.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWI-SNF_Ssr4 PF08549.10 OAG04532.1 - 0.032 12.9 4.7 0.038 12.7 4.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Suf PF05843.14 OAG04532.1 - 3.1 7.7 6.1 5.3 6.9 6.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glyco_hydro_3_C PF01915.22 OAG04533.1 - 3.3e-54 183.9 0.4 1.2e-53 182.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG04533.1 - 4.3e-45 154.5 0.0 6.9e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG04533.1 - 1.6e-21 76.2 0.0 2.8e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Dak1_2 PF13684.6 OAG04533.1 - 0.23 10.5 1.1 7.6 5.5 0.2 2.7 3 0 0 3 3 3 0 Dihydroxyacetone kinase family DUF3328 PF11807.8 OAG04535.1 - 1.4e-26 93.6 0.0 1.8e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peroxidase_ext PF11895.8 OAG04536.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Fungal peroxidase extension region DUF3328 PF11807.8 OAG04537.1 - 2.1e-29 102.9 7.1 1.6e-27 96.7 7.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) GATase PF00117.28 OAG04538.1 - 1.6e-45 155.3 0.0 2.2e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 OAG04538.1 - 3.9e-45 152.8 0.0 7.1e-45 152.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 OAG04538.1 - 0.0015 18.4 0.4 0.01 15.6 0.4 2.2 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 OAG04538.1 - 0.0062 16.4 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 DJ-1/PfpI family 2-oxogl_dehyd_N PF16078.5 OAG04538.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus YabA PF06156.13 OAG04539.1 - 0.11 13.1 2.9 25 5.6 0.0 2.7 2 0 0 2 2 2 0 Initiation control protein YabA VASt PF16016.5 OAG04540.1 - 9.3e-35 120.3 0.0 1.7e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OAG04540.1 - 3e-21 75.4 0.0 5.5e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf_C2H2_10 PF18414.1 OAG04541.1 - 0.016 14.8 1.6 0.016 14.8 1.6 2.2 3 0 0 3 3 3 0 C2H2 type zinc-finger PhnA_Zn_Ribbon PF08274.12 OAG04541.1 - 0.027 14.4 0.0 2.6 8.1 0.4 2.5 1 1 1 2 2 2 0 PhnA Zinc-Ribbon DUF898 PF05987.13 OAG04541.1 - 0.03 13.4 0.4 0.036 13.1 0.3 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) RNHCP PF12647.7 OAG04541.1 - 0.039 13.9 0.9 0.064 13.2 0.9 1.4 1 0 0 1 1 1 0 RNHCP domain Epimerase PF01370.21 OAG04543.1 - 2.4e-28 99.2 0.0 3.5e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG04543.1 - 2.9e-21 76.2 0.0 1.8e-19 70.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG04543.1 - 1.2e-12 47.4 0.0 1.7e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG04543.1 - 1.4e-10 40.8 0.0 2.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG04543.1 - 7.9e-09 35.0 0.0 9.7e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAG04543.1 - 2.3e-08 33.5 0.0 1.6e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 OAG04543.1 - 6.9e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 OAG04543.1 - 1.1e-06 28.7 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG04543.1 - 1.3e-06 28.4 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG04543.1 - 4.8e-05 23.0 0.0 7.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 OAG04543.1 - 0.024 14.2 0.0 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Acyltransferase PF01553.21 OAG04544.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 1 0 1 1 1 0 Acyltransferase NIF PF03031.18 OAG04545.1 - 3.3e-54 182.9 0.1 4.6e-54 182.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Kinesin PF00225.23 OAG04546.1 - 3e-102 342.0 0.7 3e-102 342.0 0.7 2.5 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OAG04546.1 - 1.7e-58 196.8 0.0 1.7e-58 196.8 0.0 2.4 2 1 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 OAG04546.1 - 0.0021 18.5 0.0 0.0021 18.5 0.0 3.4 2 1 0 2 2 2 1 AAA ATPase domain Filament PF00038.21 OAG04546.1 - 1.4 8.5 52.2 2.2 7.8 17.0 3.3 1 1 1 2 2 2 0 Intermediate filament protein VirE PF05272.11 OAG04546.1 - 2.2 8.0 8.5 6 6.5 0.6 2.5 2 0 0 2 2 2 0 Virulence-associated protein E Glyco_hydro_79C PF16862.5 OAG04547.1 - 3.5e-20 72.8 0.1 1.1e-19 71.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain ADH_zinc_N PF00107.26 OAG04548.1 - 4.6e-17 62.2 0.0 7.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG04548.1 - 5.1e-17 63.2 0.1 8.2e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG04548.1 - 6.6e-09 35.6 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG04548.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus XFP_C PF09363.10 OAG04548.1 - 0.14 11.6 0.0 0.36 10.3 0.0 1.6 1 1 0 1 1 1 0 XFP C-terminal domain DUF1349 PF07081.11 OAG04550.1 - 2.6e-22 79.4 0.0 1.5e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Bin3 PF06859.12 OAG04551.1 - 2.3e-26 92.5 0.0 3.1e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 OAG04551.1 - 4e-11 43.0 0.0 5.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG04551.1 - 8e-08 32.9 0.0 8.4e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG04551.1 - 1.6e-07 32.0 0.0 6.6e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG04551.1 - 2e-07 30.9 0.0 7.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG04551.1 - 1.7e-06 28.6 0.0 0.00024 21.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 OAG04551.1 - 0.0095 15.5 0.0 0.022 14.3 0.0 1.6 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.17 OAG04551.1 - 0.025 14.1 0.0 0.098 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_18 PF12847.7 OAG04551.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OAG04551.1 - 0.044 13.2 0.1 0.069 12.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 OAG04551.1 - 0.15 11.4 0.1 3.1 7.0 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase domain Methyltransf_9 PF08003.11 OAG04551.1 - 0.15 11.0 0.0 0.31 9.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) MTS PF05175.14 OAG04551.1 - 0.17 11.4 0.0 0.58 9.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 OAG04551.1 - 0.23 10.7 0.0 1.4 8.2 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Velvet PF11754.8 OAG04552.1 - 3.4e-61 207.4 0.1 1.1e-37 130.4 0.0 2.4 1 1 1 2 2 2 2 Velvet factor CTP_synth_N PF06418.14 OAG04553.1 - 8.6e-125 415.4 0.7 1.2e-124 414.9 0.7 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OAG04553.1 - 4.8e-56 189.6 0.0 7.7e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAG04553.1 - 4e-06 26.7 1.6 4.9e-05 23.2 0.5 3.0 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 OAG04553.1 - 0.011 15.7 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2883 PF11097.8 OAG04554.1 - 0.089 12.9 0.0 0.099 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) Cofilin_ADF PF00241.20 OAG04555.1 - 6.4e-34 116.3 0.0 1.6e-17 63.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 OAG04556.1 - 4.3e-69 228.5 0.5 3.2e-22 78.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein U3_snoRNA_assoc PF08297.11 OAG04557.1 - 2.3e-17 63.5 1.4 2.3e-17 63.5 1.4 5.3 5 1 0 5 5 5 1 U3 snoRNA associated dbPDZ_assoc PF16610.5 OAG04557.1 - 0.17 12.1 11.2 0.52 10.6 2.2 3.7 2 1 1 3 3 3 0 Unstructured region between two PDZ domains on Dlg5 TPR_12 PF13424.6 OAG04558.1 - 0.0012 19.1 1.3 0.0038 17.5 0.6 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG04558.1 - 0.0045 17.5 8.2 1.7 9.5 0.1 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG04558.1 - 0.014 15.7 3.6 22 5.7 0.2 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG04558.1 - 0.084 13.1 1.4 0.53 10.6 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG04558.1 - 0.11 12.7 1.8 0.52 10.6 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 OAG04558.1 - 0.2 12.4 11.3 5.8 7.7 0.1 5.4 5 0 0 5 5 5 0 Sel1 repeat TPR_19 PF14559.6 OAG04558.1 - 0.22 12.1 11.7 7.2 7.2 0.0 4.2 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG04558.1 - 8.6 7.5 10.4 10 7.3 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat Isochorismatase PF00857.20 OAG04559.1 - 9.3e-30 104.1 0.0 4e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Isochorismatase family F-box-like PF12937.7 OAG04560.1 - 4.8e-06 26.4 1.8 5.7e-05 22.9 0.2 3.0 3 0 0 3 3 3 1 F-box-like Nsp2a_N PF17896.1 OAG04560.1 - 0.25 10.5 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain F-box PF00646.33 OAG04560.1 - 0.39 10.7 4.5 1.4 8.9 1.4 3.2 2 1 0 2 2 2 0 F-box domain ETF PF01012.21 OAG04561.1 - 2.5e-43 148.1 0.9 3e-43 147.8 0.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain COesterase PF00135.28 OAG04562.1 - 2.9e-79 267.3 0.0 4e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG04562.1 - 2.1e-08 34.3 0.1 7.7e-08 32.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG04562.1 - 0.0011 18.5 0.2 0.002 17.6 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Aida_C2 PF14186.6 OAG04563.1 - 0.14 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Cytoskeletal adhesion RAI16-like PF10257.9 OAG04565.1 - 3.9e-83 279.3 0.7 6.4e-83 278.6 0.7 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein KinB_sensor PF16767.5 OAG04565.1 - 0.11 13.0 0.7 0.48 10.9 0.1 2.2 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Glyco_hydro_42 PF02449.15 OAG04565.1 - 0.23 10.7 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase ETX_MTX2 PF03318.13 OAG04566.1 - 0.0002 21.2 7.3 0.00028 20.7 7.3 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 EstA_Ig_like PF18435.1 OAG04566.1 - 0.01 16.0 0.1 0.031 14.4 0.1 1.8 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain PBP-Tp47_a PF14889.6 OAG04566.1 - 0.022 14.4 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a DUF1442 PF07279.11 OAG04566.1 - 0.09 12.1 0.2 0.19 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) DnaGprimase_HBD PF16730.5 OAG04566.1 - 0.094 12.8 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain DUF4402 PF14352.6 OAG04566.1 - 0.11 13.1 11.9 0.079 13.6 8.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4402) IIGP PF05049.13 OAG04567.1 - 5e-06 25.8 0.4 0.0079 15.3 0.0 3.1 3 0 0 3 3 3 2 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 OAG04567.1 - 8.5e-05 22.7 0.0 0.00085 19.4 0.0 2.6 2 1 1 3 3 3 1 Dynamin family AAA_22 PF13401.6 OAG04567.1 - 0.00091 19.5 0.0 0.005 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG04567.1 - 0.0038 17.3 0.2 2 8.5 0.0 3.2 3 1 0 3 3 3 1 50S ribosome-binding GTPase TBD PF12845.7 OAG04567.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 TBD domain Peptidase_C50 PF03568.17 OAG04567.1 - 0.07 12.2 1.9 0.72 8.9 0.1 2.9 3 0 0 3 3 3 0 Peptidase family C50 CAAP1 PF15335.6 OAG04567.1 - 0.13 12.8 0.5 0.46 11.1 0.5 1.9 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 AAA_16 PF13191.6 OAG04567.1 - 0.17 12.2 1.2 1.5 9.2 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain Cofilin_ADF PF00241.20 OAG04568.1 - 2.6e-07 30.5 0.0 1.4e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein Microcin PF03526.13 OAG04569.1 - 0.079 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein bVLRF1 PF18826.1 OAG04570.1 - 3.2e-59 199.1 0.6 3.2e-59 199.1 0.6 1.5 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 OAG04570.1 - 2.7e-05 24.3 0.1 8.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG04570.1 - 0.017 15.6 0.0 0.046 14.3 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 OAG04570.1 - 0.02 15.4 0.1 0.045 14.2 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat zf-C2H2 PF00096.26 OAG04570.1 - 0.1 13.1 0.6 0.21 12.1 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type CDC45 PF02724.14 OAG04570.1 - 0.25 9.6 9.9 1.8 6.7 0.0 2.1 2 0 0 2 2 2 0 CDC45-like protein zf-C2H2_3rep PF18868.1 OAG04570.1 - 0.26 12.0 1.2 0.61 10.8 0.0 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF4336 PF14234.6 OAG04571.1 - 3.4e-19 69.2 0.1 6.5e-14 51.9 0.1 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) RNase_PH PF01138.21 OAG04572.1 - 3.2e-21 76.2 0.0 4.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAG04572.1 - 2.1e-08 34.0 0.0 4.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 OAG04573.1 - 1.9e-85 286.6 25.9 2.3e-85 286.3 25.9 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 OAG04573.1 - 0.0058 16.3 5.8 0.012 15.3 5.8 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 OAG04573.1 - 0.57 10.6 6.3 0.48 10.9 4.8 1.5 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) IMUP PF15761.5 OAG04573.1 - 0.83 10.4 8.6 2.1 9.1 8.6 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein CDC45 PF02724.14 OAG04573.1 - 1.7 6.8 18.9 2 6.6 18.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 OAG04573.1 - 4.5 6.0 10.0 5.6 5.6 10.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tyrosinase PF00264.20 OAG04575.1 - 1.6e-49 169.2 0.4 1.9e-49 168.9 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Lectin_leg-like PF03388.13 OAG04576.1 - 9e-67 224.8 0.0 1.1e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 OAG04576.1 - 2.3e-08 34.3 0.2 3.3e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 OAG04576.1 - 0.0022 17.5 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.15 OAG04577.1 - 3.5e-24 84.2 1.0 4.4e-24 83.9 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pyr_redox_2 PF07992.14 OAG04579.1 - 6.2e-27 94.6 0.1 2.1e-26 92.9 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG04579.1 - 4.9e-11 43.0 0.1 1.3e-10 41.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG04579.1 - 3.1e-05 23.2 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 OAG04579.1 - 0.00025 20.3 0.0 0.00062 19.0 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG04579.1 - 0.00087 18.6 0.1 0.0088 15.3 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ribonuclease PF00545.20 OAG04581.1 - 3.2e-09 37.4 0.0 4.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 ribonuclease RRM_1 PF00076.22 OAG04582.1 - 2.3e-09 36.9 0.0 1.2e-05 25.0 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cellulase PF00150.18 OAG04583.1 - 1.1e-20 74.3 0.5 1.4e-20 73.9 0.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 OAG04583.1 - 0.008 15.3 0.2 0.031 13.4 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Transp_inhibit PF18791.1 OAG04583.1 - 0.023 14.2 0.1 0.084 12.4 0.1 1.9 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain DNMT1-RFD PF12047.8 OAG04583.1 - 0.033 14.2 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain Fungal_trans_2 PF11951.8 OAG04586.1 - 8.8e-40 136.7 0.0 1.1e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG04586.1 - 1.6e-09 37.7 10.5 3.9e-09 36.5 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AATase PF07247.12 OAG04590.1 - 3.1e-15 55.7 0.0 5.8e-11 41.6 0.0 2.5 2 1 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 OAG04590.1 - 0.013 14.2 0.3 0.013 14.2 0.3 1.3 2 0 0 2 2 2 0 Condensation domain DUF2267 PF10025.9 OAG04590.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) F-box-like PF12937.7 OAG04591.1 - 8.9e-08 31.9 0.9 2.4e-07 30.5 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG04591.1 - 0.055 13.4 0.4 0.23 11.4 0.4 2.1 1 0 0 1 1 1 0 F-box domain PTR2 PF00854.21 OAG04592.1 - 2.7e-67 227.3 4.8 2.7e-67 227.3 4.8 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG04592.1 - 4.4e-12 45.6 17.6 4.4e-12 45.6 17.6 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3311 PF11755.8 OAG04592.1 - 0.0012 18.7 0.0 0.0075 16.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3311) Aminotran_1_2 PF00155.21 OAG04593.1 - 4.6e-33 114.9 0.0 5.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1279 PF06916.13 OAG04594.1 - 1.6e-20 73.4 0.0 2.5e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) TauD PF02668.16 OAG04595.1 - 1.3e-51 176.0 0.9 1.4e-51 175.8 0.9 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAG04596.1 - 5.9e-33 114.2 29.6 8.5e-33 113.7 29.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_transf_34 PF05637.12 OAG04597.1 - 6.8e-09 35.8 1.0 1.2e-08 35.0 1.0 1.4 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DREV PF05219.12 OAG04599.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase AMP-binding PF00501.28 OAG04600.1 - 1.3e-97 327.1 0.0 1.6e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG04600.1 - 7.1e-11 42.9 0.1 1.6e-10 41.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5605 PF18310.1 OAG04600.1 - 0.16 11.9 0.0 0.47 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) NmrA PF05368.13 OAG04601.1 - 4.7e-16 59.1 0.0 6.3e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG04601.1 - 3.7e-14 53.0 0.0 1.3e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG04601.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OAG04601.1 - 0.0007 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAG04601.1 - 0.0014 19.1 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 OAG04601.1 - 0.0079 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 OAG04601.1 - 0.0087 15.2 0.1 0.019 14.1 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG04601.1 - 0.23 10.4 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2293 PF10056.9 OAG04602.1 - 6.9e-31 106.3 0.2 6.9e-31 106.3 0.2 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Bestrophin PF01062.21 OAG04602.1 - 0.096 12.1 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel TnpW PF14202.6 OAG04602.1 - 0.35 10.7 1.4 7 6.6 0.1 2.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpW Anoctamin PF04547.12 OAG04603.1 - 8.9e-103 344.5 7.3 1.1e-102 344.2 7.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Colicin_E5 PF12106.8 OAG04603.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Colicin E5 ribonuclease domain Glyco_hydro_10 PF00331.20 OAG04604.1 - 1.8e-100 336.2 1.7 2.1e-100 336.0 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Aldo_ket_red PF00248.21 OAG04605.1 - 2.2e-76 256.9 0.0 2.5e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 OAG04607.1 - 1.3e-07 30.9 20.6 6.8e-07 28.5 20.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG04607.1 - 0.0016 18.2 1.0 0.0016 18.2 1.0 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Aldo_ket_red PF00248.21 OAG04608.1 - 5.2e-37 127.6 0.1 6.3e-36 124.1 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_M61_N PF17899.1 OAG04608.1 - 0.0096 16.0 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M61 N-terminal domain Jag_N PF14804.6 OAG04608.1 - 0.28 11.6 1.6 34 4.9 0.3 3.1 4 0 0 4 4 4 0 Jag N-terminus DAO PF01266.24 OAG04609.1 - 3.8e-37 128.7 0.0 4.5e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG04609.1 - 3.3e-09 36.9 0.1 1.4e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG04609.1 - 7.7e-07 28.7 0.2 0.00093 18.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG04609.1 - 3.1e-05 24.1 0.2 0.00012 22.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG04609.1 - 0.0014 17.9 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAG04609.1 - 0.0031 16.8 0.1 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG04609.1 - 0.0054 15.8 0.1 0.26 10.3 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG04609.1 - 0.0059 15.7 0.3 0.01 14.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain LD_cluster3 PF18180.1 OAG04609.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster3 family Amino_oxidase PF01593.24 OAG04609.1 - 0.012 15.0 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase MCRA PF06100.11 OAG04609.1 - 0.031 13.1 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 OAG04609.1 - 0.043 12.5 0.1 1.2 7.8 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein DUF1818 PF08848.11 OAG04609.1 - 0.15 12.2 0.1 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) Glyco_hydro_15 PF00723.21 OAG04611.1 - 2.2e-89 300.3 0.4 2.7e-89 300.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 OAG04611.1 - 2.5e-23 81.8 0.0 6.3e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain GAD-like PF08887.11 OAG04611.1 - 0.091 12.5 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 GAD-like domain adh_short_C2 PF13561.6 OAG04612.1 - 2.7e-60 203.9 0.2 3.1e-60 203.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG04612.1 - 3.9e-40 137.4 0.3 4.6e-40 137.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG04612.1 - 4.2e-15 56.1 0.3 6.4e-15 55.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Spore_IV_A PF09547.10 OAG04612.1 - 0.049 12.6 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Polysacc_synt_2 PF02719.15 OAG04612.1 - 0.05 12.7 0.1 0.068 12.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_23 PF13489.6 OAG04614.1 - 3.3e-22 79.1 0.0 4.9e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG04614.1 - 1e-12 48.1 0.0 4.3e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG04614.1 - 1.6e-10 41.5 0.0 2.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG04614.1 - 1.1e-09 38.9 0.0 4.7e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG04614.1 - 1.8e-07 31.7 0.0 3.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 OAG04614.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 OAG04614.1 - 0.046 13.5 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase MTS PF05175.14 OAG04614.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.12 OAG04614.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Glyco_hydro_3 PF00933.21 OAG04615.1 - 1.4e-49 169.2 0.0 2.1e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAG04615.1 - 1.1e-47 162.6 0.0 1.7e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OAG04615.1 - 1.7e-13 50.4 1.8 3.4e-13 49.5 1.2 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 OAG04615.1 - 1.8e-09 37.6 0.0 5.1e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 PA14 domain NAD_binding_10 PF13460.6 OAG04616.1 - 7.2e-15 55.3 0.0 9.7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG04616.1 - 2.3e-07 30.5 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG04616.1 - 6.7e-05 22.6 0.2 8.9e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OAG04616.1 - 0.00022 20.5 0.1 0.00029 20.1 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 OAG04616.1 - 0.00029 21.2 0.0 0.00049 20.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG04616.1 - 0.00081 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 OAG04616.1 - 0.005 17.4 0.0 0.0097 16.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 OAG04616.1 - 0.011 15.2 0.1 0.021 14.3 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 OAG04616.1 - 0.017 14.1 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 OAG04616.1 - 0.034 14.3 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.12 OAG04616.1 - 0.079 12.1 0.6 0.33 10.1 0.6 2.0 1 1 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 OAG04616.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Abhydrolase_3 PF07859.13 OAG04617.1 - 4.2e-19 69.3 0.1 8e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG04617.1 - 5.3e-17 61.7 0.0 7.7e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 OAG04617.1 - 0.044 13.6 0.0 0.51 10.1 0.0 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF4022 PF13214.6 OAG04618.1 - 0.69 10.2 6.1 0.15 12.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) Ricin_B_lectin PF00652.22 OAG04619.1 - 9.8e-16 58.2 4.2 1.2e-08 35.3 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OAG04619.1 - 4.4e-07 30.5 3.7 0.00023 21.8 1.2 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like PS-DH PF14765.6 OAG04619.1 - 0.054 12.7 0.0 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 Polyketide synthase dehydratase LUC7 PF03194.15 OAG04620.1 - 0.072 12.7 1.3 0.13 12.0 1.2 1.5 1 1 0 1 1 1 0 LUC7 N_terminus dCMP_cyt_deam_1 PF00383.23 OAG04621.1 - 3.5e-12 46.1 0.0 5.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG04621.1 - 3.3e-07 30.2 0.0 6.9e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 MafB19-like deaminase WD40 PF00400.32 OAG04623.1 - 5.5e-11 42.8 1.0 0.037 14.9 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OAG04623.1 - 8.2e-06 24.8 0.0 0.0059 15.4 0.0 3.1 2 1 1 3 3 3 3 Nup133 N terminal like Sdh_cyt PF01127.22 OAG04624.1 - 9.1e-25 87.0 6.1 1.1e-24 86.8 6.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Tudor_3 PF18115.1 OAG04625.1 - 1.3e-15 56.9 0.0 5.8e-15 54.9 0.0 2.2 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 OAG04625.1 - 9.4e-09 35.5 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 OAG04625.1 - 3.3e-08 33.8 0.0 7.6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OAG04625.1 - 0.0026 17.6 0.0 0.0079 16.1 0.0 1.8 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 OAG04625.1 - 0.093 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Glyco_transf_25 PF01755.17 OAG04626.1 - 4.1e-07 30.1 0.6 2.1e-05 24.5 0.6 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-RanBP PF00641.18 OAG04628.1 - 9.1e-20 69.7 10.6 1.8e-10 39.9 2.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 OAG04628.1 - 2.2e-07 30.6 0.0 4.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 OAG04628.1 - 7e-07 29.9 0.0 1e-06 29.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 OAG04628.1 - 8 6.0 6.6 1.1 8.7 0.4 2.6 3 0 0 3 3 3 0 zinc-ribbon domain F-box-like PF12937.7 OAG04629.1 - 1.4e-06 28.1 0.0 3.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like PH PF00169.29 OAG04632.1 - 3.5e-05 24.3 0.6 6.8e-05 23.3 0.6 1.4 1 0 0 1 1 1 1 PH domain DDHD PF02862.17 OAG04632.1 - 0.64 10.1 4.1 1.9 8.6 4.1 1.8 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.11 OAG04632.1 - 5 5.5 17.5 7.4 4.9 17.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Glycogen_syn PF05693.13 OAG04633.1 - 0 1141.7 0.0 0 1141.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 OAG04633.1 - 2e-05 24.2 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG04633.1 - 0.0001 22.8 0.0 0.00021 21.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 OAG04633.1 - 0.00021 21.3 0.2 0.00041 20.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAG04633.1 - 0.00024 21.5 0.0 0.22 12.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAG04633.1 - 0.0014 18.4 0.0 0.0037 17.0 0.0 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain TrkH PF02386.16 OAG04634.1 - 1.7e-147 491.9 7.2 1.2e-146 489.1 3.1 2.1 2 0 0 2 2 2 2 Cation transport protein FtsJ PF01728.19 OAG04635.1 - 6.8e-12 45.8 0.0 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 OAG04635.1 - 0.13 13.3 0.1 1.4 9.9 0.0 2.6 3 1 0 3 3 3 0 Methyltransferase domain adh_short PF00106.25 OAG04637.1 - 1.2e-46 158.7 1.0 1.4e-46 158.4 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04637.1 - 3e-44 151.3 1.8 1e-40 139.8 1.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04637.1 - 2.5e-16 60.1 0.3 3.7e-16 59.5 0.3 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG04637.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAG04637.1 - 0.0017 17.9 0.6 0.0033 16.9 0.6 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG04637.1 - 0.016 14.6 0.1 0.063 12.7 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 OAG04637.1 - 0.027 13.8 0.7 0.05 12.9 0.7 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.6 OAG04638.1 - 2.1e-55 187.8 0.5 2.6e-55 187.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG04638.1 - 5.7e-46 156.4 0.4 7.7e-46 156.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG04638.1 - 1.6e-07 31.4 0.2 4.4e-07 30.0 0.3 1.6 1 1 0 1 1 1 1 KR domain TRI12 PF06609.13 OAG04640.1 - 8.1e-198 658.6 23.6 1e-197 658.2 23.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG04640.1 - 3.7e-17 62.3 28.9 3.7e-17 62.3 28.9 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04640.1 - 9.5e-12 44.5 8.8 9.5e-12 44.5 8.8 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_32N PF00251.20 OAG04641.1 - 0.0013 18.3 0.1 0.0029 17.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 OAG04641.1 - 0.0016 17.8 0.7 0.055 12.8 1.7 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 TPR_2 PF07719.17 OAG04642.1 - 2e-30 102.4 14.4 0.00024 21.0 0.4 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 OAG04642.1 - 2.9e-30 102.8 6.0 2e-05 24.2 1.1 10.6 11 0 0 11 11 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG04642.1 - 8.8e-29 99.6 9.3 2.5e-24 85.3 0.7 4.9 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OAG04642.1 - 9.7e-23 78.4 0.2 0.0021 18.1 0.3 9.3 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG04642.1 - 1.6e-22 79.7 12.0 8e-05 23.1 0.1 8.2 5 2 3 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAG04642.1 - 1.2e-17 64.0 21.1 1e-08 35.3 0.2 8.7 7 1 3 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG04642.1 - 2.1e-15 56.1 20.2 0.03 15.1 0.1 11.4 5 3 7 12 12 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG04642.1 - 3.1e-15 56.5 13.9 3.1e-05 24.5 0.2 7.8 5 3 4 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAG04642.1 - 4.4e-13 48.7 7.7 0.17 11.6 0.0 7.9 6 2 3 9 9 8 4 TPR repeat TPR_7 PF13176.6 OAG04642.1 - 3.2e-09 36.2 17.0 0.25 11.5 0.0 8.8 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG04642.1 - 1.3e-08 34.6 3.8 0.19 12.2 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG04642.1 - 1.4e-08 34.7 9.3 0.0064 16.6 0.5 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG04642.1 - 2e-08 34.4 11.4 0.85 10.4 0.2 7.6 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG04642.1 - 4.6e-07 29.3 1.5 0.06 12.5 0.0 5.1 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAG04642.1 - 1.6e-05 25.1 4.9 0.31 11.8 0.1 5.9 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 OAG04642.1 - 2.1e-05 24.3 3.3 0.0073 16.0 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 OAG04642.1 - 4.1e-05 23.1 6.1 0.0033 16.8 0.1 4.4 4 2 1 5 5 5 1 MalT-like TPR region PPR PF01535.20 OAG04642.1 - 0.00016 21.7 0.9 1 9.8 0.0 4.9 4 0 0 4 4 4 1 PPR repeat TPR_10 PF13374.6 OAG04642.1 - 0.00017 21.3 13.6 0.071 13.0 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.6 OAG04642.1 - 0.00079 18.9 0.4 1.6 8.1 0.0 3.9 4 1 0 4 4 4 1 Soluble NSF attachment protein, SNAP NARP1 PF12569.8 OAG04642.1 - 0.0015 17.6 0.3 0.18 10.7 0.0 3.1 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 ST7 PF04184.12 OAG04642.1 - 0.013 14.0 0.1 0.37 9.2 0.1 2.1 2 0 0 2 2 2 0 ST7 protein HrpB1_HrpK PF09613.10 OAG04642.1 - 0.018 14.7 0.1 0.28 10.8 0.2 2.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_5 PF12688.7 OAG04642.1 - 0.018 15.3 1.3 0.097 12.9 0.1 2.7 3 0 0 3 3 2 0 Tetratrico peptide repeat SRP_TPR_like PF17004.5 OAG04642.1 - 0.041 13.9 0.0 0.59 10.2 0.0 2.8 2 0 0 2 2 2 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 OAG04642.1 - 0.077 13.1 5.1 5.6 7.1 0.3 4.3 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat PPR_2 PF13041.6 OAG04642.1 - 0.1 12.8 1.0 6.4 7.1 0.0 3.7 4 0 0 4 4 3 0 PPR repeat family DUF572 PF04502.13 OAG04643.1 - 2.8e-70 237.6 20.1 7.1e-70 236.2 20.3 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 OAG04643.1 - 0.017 15.2 2.6 0.13 12.4 0.4 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF866 PF05907.13 OAG04643.1 - 0.032 14.1 0.7 0.06 13.3 0.7 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Acyl-CoA_dh_1 PF00441.24 OAG04644.1 - 2.4e-29 102.5 0.1 3.5e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG04644.1 - 2.7e-24 85.2 0.1 4.3e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG04644.1 - 3.3e-21 76.0 0.1 9.4e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG04644.1 - 0.0024 18.2 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ig_GlcNase PF18368.1 OAG04645.1 - 4.5e-29 100.7 0.1 1.5e-28 99.0 0.1 1.9 1 1 0 1 1 1 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 OAG04645.1 - 1.6e-13 51.3 0.0 4.9e-11 43.3 0.0 3.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 OAG04645.1 - 3.8e-06 27.4 0.1 2.9e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 OAG04645.1 - 0.017 14.3 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 OAG04645.1 - 0.1 12.4 0.2 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Ig-fold domain HATPase_c PF02518.26 OAG04646.1 - 3.5e-23 82.3 0.0 2.6e-22 79.5 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG04646.1 - 1.5e-21 76.7 0.4 1.8e-20 73.2 0.4 2.5 1 1 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAG04646.1 - 1.7e-07 31.4 0.1 5.7e-07 29.8 0.1 2.0 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAG04646.1 - 2.6e-07 30.6 0.0 8.4e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 OAG04646.1 - 3.2e-07 30.3 0.0 8.4e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAG04646.1 - 1.6e-06 28.3 0.3 7.1e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 PAS fold DUF1828 PF08861.10 OAG04646.1 - 0.0047 17.2 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF1828 PAS_8 PF13188.7 OAG04646.1 - 0.02 14.9 0.0 0.07 13.2 0.0 2.0 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 OAG04646.1 - 0.025 14.8 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 PAS domain HATPase_c_3 PF13589.6 OAG04646.1 - 0.086 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Beta-APP PF03494.13 OAG04647.1 - 0.17 11.8 1.2 0.33 10.8 1.2 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Amnionless PF14828.6 OAG04647.1 - 1.2 7.8 3.6 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 Amnionless DUF5601 PF18151.1 OAG04648.1 - 0.073 13.4 0.1 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) adh_short_C2 PF13561.6 OAG04649.1 - 8.5e-15 54.9 2.0 1.1e-14 54.5 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG04649.1 - 7.8e-12 45.1 0.4 9.5e-12 44.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OAG04649.1 - 7e-06 25.7 0.0 9.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG04649.1 - 4e-05 23.6 1.4 4.1e-05 23.6 0.4 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG04649.1 - 4.5e-05 22.7 0.2 5.8e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 OAG04649.1 - 0.0011 18.9 0.5 0.013 15.4 0.1 2.1 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 OAG04649.1 - 0.0022 17.9 0.6 0.0057 16.6 0.6 1.8 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 OAG04649.1 - 0.0073 15.9 1.7 0.04 13.5 1.7 2.1 1 1 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.19 OAG04649.1 - 0.016 14.6 0.1 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG04649.1 - 0.025 14.0 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 OAG04649.1 - 0.055 13.6 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SusE PF14292.6 OAG04649.1 - 0.11 12.7 3.2 0.12 12.6 1.8 1.8 1 1 1 2 2 2 0 SusE outer membrane protein Amidohydro_3 PF07969.11 OAG04652.1 - 8.8e-68 229.9 7.0 1.1e-67 229.6 7.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG04652.1 - 1.3e-12 47.8 0.7 2.3e-07 30.5 0.3 2.9 2 1 0 2 2 2 2 Amidohydrolase family MLD PF11647.8 OAG04652.1 - 0.086 13.1 0.1 3.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Membrane Localization Domain Zn_clus PF00172.18 OAG04653.1 - 8.6e-05 22.6 11.0 0.00015 21.8 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG04653.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain YbjQ_1 PF01906.17 OAG04654.1 - 3.8e-22 78.9 1.0 4.6e-22 78.6 1.0 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding F-box-like PF12937.7 OAG04655.1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like Aa_trans PF01490.18 OAG04657.1 - 3.2e-37 128.2 32.0 3.7e-37 128.0 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 OAG04657.1 - 3.3e-07 29.5 26.2 3.3e-07 29.5 26.2 2.1 1 1 0 2 2 2 1 Amino acid permease CstA PF02554.14 OAG04657.1 - 8.8e-05 21.6 9.9 8.8e-05 21.6 9.9 1.9 2 0 0 2 2 2 1 Carbon starvation protein CstA Spore_permease PF03845.13 OAG04657.1 - 0.00075 18.4 34.9 0.0084 15.0 19.3 3.0 2 1 0 2 2 2 2 Spore germination protein Trp_Tyr_perm PF03222.13 OAG04657.1 - 0.00099 18.2 15.0 0.00099 18.2 15.0 2.5 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family MGC-24 PF05283.11 OAG04659.1 - 0.0089 16.5 3.9 0.015 15.7 3.9 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin CD34_antigen PF06365.12 OAG04659.1 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4690 PF15756.5 OAG04659.1 - 0.022 15.3 1.1 0.049 14.2 1.1 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Chordopox_A13L PF05961.11 OAG04659.1 - 0.032 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Alpha_GJ PF03229.13 OAG04659.1 - 0.095 13.3 6.2 0.22 12.0 6.2 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J FtsX PF02687.21 OAG04659.1 - 1.2 9.7 4.4 19 5.8 0.1 2.5 2 1 0 2 2 2 0 FtsX-like permease family DUF3123 PF11321.8 OAG04659.1 - 6.2 7.5 7.2 1.1 9.9 3.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DEAD PF00270.29 OAG04660.1 - 3e-41 141.1 0.1 5.7e-41 140.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG04660.1 - 4e-32 110.8 0.1 1.5e-31 109.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG04660.1 - 0.00039 20.2 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG04660.1 - 0.0014 19.0 0.0 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OAG04660.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 OAG04660.1 - 0.025 14.6 0.6 0.077 13.0 0.1 2.2 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 OAG04660.1 - 0.068 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 OAG04660.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Helicase DUF5393 PF17371.2 OAG04660.1 - 0.098 10.8 0.1 0.18 9.9 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5393) tRNA-synt_1b PF00579.25 OAG04660.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) DUF3449 PF11931.8 OAG04661.1 - 1.3e-78 263.0 0.8 2.6e-78 262.0 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 OAG04661.1 - 2e-26 92.3 1.7 2e-26 92.3 1.7 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 OAG04661.1 - 5.4e-09 36.1 0.8 5.4e-09 36.1 0.8 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG04661.1 - 1.2e-07 31.9 3.0 2e-07 31.1 0.9 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAG04661.1 - 0.00078 19.7 0.2 0.0082 16.5 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) PRP9_N PF16958.5 OAG04661.1 - 0.0012 18.9 8.2 0.017 15.2 1.6 3.4 2 1 1 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus SF3a60_bindingd PF12108.8 OAG04661.1 - 0.027 14.3 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain zf-DBF PF07535.12 OAG04661.1 - 4.1 7.6 6.5 0.89 9.7 0.5 2.7 2 1 0 2 2 2 0 DBF zinc finger DDR PF08841.10 OAG04665.1 - 0.0043 16.1 1.4 0.044 12.8 0.8 2.2 1 1 1 2 2 2 1 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 OAG04665.1 - 0.016 13.4 0.2 0.046 11.9 0.0 1.7 2 0 0 2 2 2 0 Hsp70 protein MreB_Mbl PF06723.13 OAG04665.1 - 0.037 12.9 0.2 1.9 7.2 0.2 2.4 2 0 0 2 2 2 0 MreB/Mbl protein PilM_2 PF11104.8 OAG04665.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Ribonucleas_3_3 PF14622.6 OAG04666.1 - 9.2e-11 42.0 0.0 1.1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG04666.1 - 2.7e-06 27.9 0.0 1.1e-05 26.0 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain PhyH PF05721.13 OAG04667.1 - 4.1e-20 72.9 0.0 7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4407 PF14362.6 OAG04669.1 - 0.034 13.5 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pro_Al_protease PF02983.14 OAG04669.1 - 0.04 14.0 2.5 0.04 14.0 2.5 3.1 3 0 0 3 3 3 0 Alpha-lytic protease prodomain Peptidase_C27 PF05407.12 OAG04669.1 - 0.057 13.5 9.9 0.38 10.8 9.9 2.1 1 1 0 1 1 1 0 Rubella virus endopeptidase KfrA_N PF11740.8 OAG04669.1 - 0.76 10.5 13.0 0.4 11.4 4.7 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Mobilization_B PF17511.2 OAG04669.1 - 1.5 9.2 10.4 2.2 8.6 1.8 2.2 2 0 0 2 2 2 0 Mobilization protein B Uso1_p115_C PF04871.13 OAG04669.1 - 3.5 8.0 7.6 4.3 7.7 3.8 2.2 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GFA PF04828.14 OAG04670.1 - 9.5e-10 38.7 1.3 9.5e-10 38.7 1.3 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Kelch_3 PF13415.6 OAG04671.1 - 1.1 9.7 3.7 5.2 7.5 0.1 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain zf-CHY PF05495.12 OAG04672.1 - 1.2e-13 51.3 15.1 2.5e-13 50.3 15.1 1.5 1 1 0 1 1 1 1 CHY zinc finger zf_UBZ PF18439.1 OAG04672.1 - 0.0022 17.5 6.0 1.1 8.9 0.2 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 OAG04672.1 - 0.013 15.7 3.0 0.013 15.7 3.0 2.3 1 1 1 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 OAG04672.1 - 0.041 14.0 5.9 0.041 14.0 5.9 2.6 2 1 1 3 3 3 0 Zinc ribbon domain HypA PF01155.19 OAG04672.1 - 0.23 11.5 9.4 1 9.4 9.4 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DpnI PF06044.12 OAG04672.1 - 0.41 10.3 4.4 0.28 10.8 2.2 1.7 1 1 1 2 2 2 0 Dam-replacing family zinc-ribbons_6 PF07191.12 OAG04672.1 - 0.79 9.8 12.5 0.15 12.1 2.8 2.3 1 1 2 3 3 3 0 zinc-ribbons LIM PF00412.22 OAG04672.1 - 1.1 9.5 13.9 1.4 9.2 10.4 2.4 1 1 1 2 2 2 0 LIM domain zinc_ribbon_4 PF13717.6 OAG04672.1 - 3 7.8 14.6 0.64 10.0 0.3 3.9 3 1 1 4 4 4 0 zinc-ribbon domain Evr1_Alr PF04777.13 OAG04672.1 - 3.1 8.3 11.6 2.4e+02 2.2 11.6 2.8 1 1 0 1 1 1 0 Erv1 / Alr family zf-C2H2 PF00096.26 OAG04672.1 - 3.3 8.3 11.2 2.5 8.7 1.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Proteasome PF00227.26 OAG04673.1 - 5.6e-56 189.0 0.0 7.4e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG04673.1 - 5.9e-13 48.2 0.3 2e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 OAG04673.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) FAD-oxidase_C PF02913.19 OAG04674.1 - 2.2e-60 204.4 0.0 3.1e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG04674.1 - 1.2e-34 119.0 0.3 2.3e-34 118.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Amidohydro_2 PF04909.14 OAG04675.1 - 3e-31 109.3 0.5 8.1e-31 107.9 0.5 1.6 1 1 0 1 1 1 1 Amidohydrolase MTHFR PF02219.17 OAG04676.1 - 3.6e-100 335.0 0.0 5.9e-100 334.3 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PLU-1 PF08429.11 OAG04677.1 - 0.036 13.3 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 PLU-1-like protein Glyco_hydro_43 PF04616.14 OAG04678.1 - 1.1e-65 221.9 3.8 1.5e-65 221.4 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG04678.1 - 1.3e-20 74.0 0.0 2.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 OAG04678.1 - 0.078 12.5 0.1 3.3 7.2 0.0 2.9 3 0 0 3 3 3 0 Glycosyl hydrolases family 32 N-terminal domain SnoaL_4 PF13577.6 OAG04679.1 - 1.5e-16 60.7 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 OAG04679.1 - 0.018 15.1 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit GST_C PF00043.25 OAG04680.1 - 4.5e-12 46.0 0.0 7.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG04680.1 - 2e-09 37.6 0.0 3.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG04680.1 - 7.5e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG04680.1 - 1.5e-08 34.9 0.0 2.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG04680.1 - 3.3e-08 33.4 0.2 2.3e-07 30.7 0.1 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG04680.1 - 3.5e-06 27.2 0.0 6.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DJ-1_PfpI PF01965.24 OAG04681.1 - 4.5e-14 52.6 0.0 5.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 OAG04681.1 - 0.0013 18.6 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I LapA_dom PF06305.11 OAG04682.1 - 0.061 13.2 0.3 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Monooxygenase_B PF04744.12 OAG04682.1 - 0.15 10.9 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Monooxygenase subunit B protein GTP_cyclohydroI PF01227.22 OAG04684.1 - 5.9e-74 247.4 0.2 7.6e-74 247.0 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 OAG04684.1 - 0.0021 18.2 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein HATPase_c_2 PF13581.6 OAG04684.1 - 0.12 12.3 0.2 0.28 11.2 0.2 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Pkinase PF00069.25 OAG04685.1 - 5.3e-71 239.1 0.0 8e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04685.1 - 1.8e-34 119.2 0.0 2.9e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG04685.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG04685.1 - 0.003 17.0 0.1 0.0064 15.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG04685.1 - 0.0077 15.2 0.1 0.028 13.4 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG04685.1 - 0.15 10.8 0.0 0.15 10.8 0.0 3.7 3 1 0 4 4 4 0 Fungal protein kinase BppU_N PF10651.9 OAG04686.1 - 0.084 12.6 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 BppU N-terminal domain YitT_membrane PF02588.15 OAG04686.1 - 0.1 12.0 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 FAD_binding_8 PF08022.12 OAG04687.1 - 2e-19 69.7 0.0 4.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG04687.1 - 5.6e-16 59.1 0.0 1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAG04687.1 - 6.3e-13 48.9 8.4 8.7e-13 48.5 6.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.32 OAG04687.1 - 0.0009 18.6 0.6 0.0018 17.7 0.6 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OAG04687.1 - 0.0035 17.8 0.2 0.0087 16.5 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAG04687.1 - 0.033 13.7 0.3 0.063 12.8 0.3 1.4 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 OAG04687.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair Abhydrolase_3 PF07859.13 OAG04688.1 - 1.2e-31 110.3 0.0 1.5e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG04688.1 - 4.2e-06 25.9 0.0 5.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase S1-P1_nuclease PF02265.16 OAG04689.1 - 2.2e-71 240.6 0.6 3.1e-71 240.2 0.6 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease Lipase_3 PF01764.25 OAG04691.1 - 9.4e-36 122.8 0.0 1.4e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 OAG04691.1 - 9.4e-09 35.2 0.1 1.9e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.8 OAG04691.1 - 3.2e-05 23.6 0.8 9.7e-05 22.0 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 OAG04691.1 - 0.00013 21.4 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG04691.1 - 0.0095 16.6 0.0 0.013 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 OAG04691.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Herpes_UL74 PF07982.12 OAG04691.1 - 0.024 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Cutinase PF01083.22 OAG04691.1 - 0.03 14.3 0.6 0.077 12.9 0.0 2.0 3 0 0 3 3 3 0 Cutinase Thioesterase PF00975.20 OAG04691.1 - 0.2 11.8 0.1 0.51 10.4 0.1 1.6 1 1 1 2 2 2 0 Thioesterase domain PQ-loop PF04193.14 OAG04692.1 - 5.7e-39 131.7 18.7 1.5e-20 72.7 2.8 2.9 3 0 0 3 3 3 2 PQ loop repeat TPR_1 PF00515.28 OAG04693.1 - 1e-05 25.1 0.3 0.77 9.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG04693.1 - 5.9e-05 22.9 0.9 5.3 7.4 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG04693.1 - 0.022 15.0 0.1 75 3.7 0.0 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 OAG04693.1 - 0.093 12.9 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 DnaJ domain DUF1688 PF07958.11 OAG04694.1 - 8.5e-183 607.8 0.0 9.7e-183 607.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.12 OAG04695.1 - 6.4e-91 303.8 0.2 7.7e-91 303.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG04695.1 - 1.1e-08 35.3 0.0 2.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG04695.1 - 1.9e-08 34.1 0.0 4.8e-08 32.8 0.0 1.6 1 1 1 2 2 2 1 Ras family Arf PF00025.21 OAG04695.1 - 3.5e-08 33.1 0.0 8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG04695.1 - 6e-07 29.6 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG04695.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.13 OAG04695.1 - 0.0022 17.2 0.1 0.0045 16.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 OAG04695.1 - 0.0023 17.8 0.2 0.14 12.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 OAG04695.1 - 0.035 14.6 0.0 0.078 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 OAG04695.1 - 0.04 13.1 5.6 0.8 8.8 0.1 3.0 1 1 2 3 3 3 0 G-protein alpha subunit AAA_29 PF13555.6 OAG04695.1 - 0.062 13.1 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 OAG04695.1 - 0.13 11.9 0.5 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase AAA_16 PF13191.6 OAG04695.1 - 0.17 12.3 0.3 0.66 10.3 0.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.16 OAG04695.1 - 0.21 10.9 1.3 0.91 8.8 1.3 2.0 1 1 0 1 1 1 0 AIG1 family Fungal_trans PF04082.18 OAG04696.1 - 7e-11 41.7 1.5 3.6e-10 39.3 0.0 2.6 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG04696.1 - 3.2e-05 24.0 10.8 6e-05 23.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CP_ATPgrasp_2 PF14403.6 OAG04696.1 - 0.047 12.6 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 WW PF00397.26 OAG04697.1 - 1.5e-06 28.2 4.9 4e-06 26.8 4.9 1.8 1 0 0 1 1 1 1 WW domain WRW PF10206.9 OAG04697.1 - 0.065 13.6 0.2 0.14 12.6 0.2 1.7 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Ank_4 PF13637.6 OAG04698.1 - 3.6e-25 88.0 3.1 3.2e-15 56.3 0.2 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG04698.1 - 4.3e-25 88.1 6.3 1.4e-16 60.9 2.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAG04698.1 - 2.2e-15 56.3 2.2 2.8e-08 33.9 0.3 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OAG04698.1 - 4.9e-13 48.0 0.1 3e-06 27.2 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG04698.1 - 9.5e-13 48.1 3.7 5.4e-08 32.9 0.5 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PE PF00934.20 OAG04698.1 - 0.23 11.8 6.8 0.16 12.3 4.9 1.8 1 1 0 1 1 1 0 PE family rhaM PF05336.13 OAG04699.1 - 0.08 13.0 0.2 0.3 11.2 0.2 1.8 2 0 0 2 2 2 0 L-rhamnose mutarotase MAP65_ASE1 PF03999.12 OAG04699.1 - 0.4 9.3 2.7 0.5 9.0 2.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Nucleo_P87 PF07267.11 OAG04699.1 - 3.9 6.2 4.2 5.7 5.7 4.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ABC2_membrane PF01061.24 OAG04700.1 - 2.3e-81 272.3 51.7 5.6e-42 143.5 25.2 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG04700.1 - 7.7e-33 113.9 0.0 2.4e-15 57.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG04700.1 - 1.3e-23 82.7 0.3 5.1e-22 77.6 0.0 3.7 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG04700.1 - 8.5e-18 64.8 0.3 2.7e-17 63.2 0.3 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG04700.1 - 7.3e-08 31.9 10.5 7.3e-08 31.9 10.5 3.1 2 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 OAG04700.1 - 1.1e-05 25.4 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAG04700.1 - 2.4e-05 24.8 0.1 0.0045 17.4 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 OAG04700.1 - 9.5e-05 22.1 1.1 0.025 14.1 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OAG04700.1 - 0.0002 21.0 0.3 0.011 15.4 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG04700.1 - 0.0022 17.9 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 OAG04700.1 - 0.0052 16.5 0.1 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG04700.1 - 0.0062 17.1 0.0 0.17 12.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 OAG04700.1 - 0.024 14.9 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 OAG04700.1 - 0.026 14.0 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG04700.1 - 0.042 14.1 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG04700.1 - 0.058 13.6 0.0 0.89 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG04700.1 - 0.38 11.2 0.0 0.38 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 OAG04700.1 - 0.55 9.8 1.7 1.3 8.6 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3237 PF11578.8 OAG04701.1 - 1.7e-24 86.3 0.2 5.4e-21 75.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) Opi1 PF08618.10 OAG04702.1 - 1e-36 127.2 15.6 8.4e-26 91.2 11.7 3.3 1 1 1 2 2 2 2 Transcription factor Opi1 BDV_P40 PF06407.11 OAG04702.1 - 0.12 11.5 0.3 0.19 10.8 0.3 1.2 1 0 0 1 1 1 0 Borna disease virus P40 protein HRDC PF00570.23 OAG04703.1 - 1.4e-21 76.2 0.0 8.9e-17 60.8 0.0 2.4 2 0 0 2 2 2 2 HRDC domain DNA_pol_A_exo1 PF01612.20 OAG04703.1 - 5.1e-14 52.4 0.0 8.1e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease TAF6_C PF07571.13 OAG04708.1 - 7e-27 93.6 0.2 2.3e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OAG04708.1 - 4.3e-24 84.5 0.1 1.1e-23 83.1 0.1 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 OAG04708.1 - 0.0044 17.4 0.1 0.0089 16.4 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OAG04708.1 - 0.0046 17.0 0.1 0.015 15.4 0.1 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PRIMA1 PF16101.5 OAG04709.1 - 0.037 14.1 2.1 0.038 14.0 2.1 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Capsid-VNN PF11729.8 OAG04710.1 - 0.4 9.6 2.6 0.47 9.4 2.6 1.1 1 0 0 1 1 1 0 nodavirus capsid protein Nucleo_P87 PF07267.11 OAG04711.1 - 0.12 11.3 3.8 0.17 10.8 3.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pox_Ag35 PF03286.14 OAG04711.1 - 0.99 9.2 9.7 0.12 12.2 5.5 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein AP3D1 PF06375.11 OAG04711.1 - 6.6 6.9 14.1 16 5.7 12.9 1.9 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 TFIIE-A_C PF11521.8 OAG04711.1 - 10 6.5 10.0 0.38 11.1 4.1 1.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Retrotran_gag_2 PF14223.6 OAG04712.1 - 6.1e-14 51.9 0.0 7.8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ketoacyl-synt_2 PF13723.6 OAG04712.1 - 0.0089 15.7 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Adap_comp_sub PF00928.21 OAG04713.1 - 4.7e-92 308.1 0.0 6.7e-92 307.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG04713.1 - 1.5e-09 38.0 0.3 2.4e-09 37.3 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AMP-binding PF00501.28 OAG04715.1 - 1.4e-09 37.1 0.0 2.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.11 OAG04716.1 - 3.9e-24 85.2 0.0 8.9e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 Nuclear pore complex component DUF4748 PF15932.5 OAG04717.1 - 1.5e-17 63.1 0.6 1.5e-17 63.1 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4748) ATP-synt_DE PF00401.20 OAG04717.1 - 0.018 15.3 3.7 0.034 14.4 3.7 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain FXMRP1_C_core PF12235.8 OAG04717.1 - 0.57 10.8 8.4 0.49 11.0 7.1 1.6 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal NAD_binding_10 PF13460.6 OAG04718.1 - 3.7e-05 23.7 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG04718.1 - 0.00011 21.7 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG04718.1 - 0.00043 19.5 0.0 0.00057 19.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OAG04718.1 - 0.0044 16.9 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 OAG04718.1 - 0.0077 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 OAG04718.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 OAG04718.1 - 0.024 15.1 0.0 0.082 13.3 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG04718.1 - 0.075 12.1 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 OAG04718.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 OAG04718.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Aldo_ket_red PF00248.21 OAG04719.1 - 6.2e-43 147.1 0.0 7e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MukE PF04288.13 OAG04719.1 - 0.021 13.8 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 MukE-like family MFS_1 PF07690.16 OAG04720.1 - 1.3e-27 96.7 25.7 1.9e-27 96.1 25.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRIQK PF15168.6 OAG04720.1 - 0.0082 16.0 0.5 3.5 7.6 0.0 3.5 3 0 0 3 3 3 1 Triple QxxK/R motif-containing protein family DUF1673 PF07895.11 OAG04720.1 - 0.13 12.0 2.7 0.47 10.1 2.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) PfkB PF00294.24 OAG04721.1 - 5.2e-55 186.9 3.9 6.2e-55 186.6 3.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MCM PF00493.23 OAG04722.1 - 1.9e-104 347.7 0.0 3.5e-104 346.8 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG04722.1 - 2.7e-36 124.2 0.4 5.4e-36 123.2 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG04722.1 - 2.3e-29 101.6 1.5 5.4e-29 100.4 1.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG04722.1 - 9.4e-16 58.3 0.3 2.6e-15 56.9 0.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG04722.1 - 9.2e-06 25.2 0.0 0.00078 18.9 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG04722.1 - 1e-05 25.6 0.1 2.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAG04722.1 - 0.00036 20.4 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG04722.1 - 0.036 13.8 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 OAG04722.1 - 0.083 13.3 0.1 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vps54 PF07928.12 OAG04723.1 - 9.1e-48 162.1 2.0 3e-47 160.4 2.0 2.0 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 OAG04723.1 - 0.00013 21.4 0.9 0.00013 21.4 0.9 2.7 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 OAG04723.1 - 0.048 12.5 0.5 0.099 11.5 0.5 1.5 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DHR10 PF18595.1 OAG04723.1 - 0.58 10.2 3.8 0.62 10.1 0.1 2.7 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain T3SS_basalb_I PF17001.5 OAG04723.1 - 4.7 7.9 5.9 3.7 8.2 0.3 3.7 4 0 0 4 4 4 0 Type III secretion basal body protein I, YscI, HrpB, PscI DSS1_SEM1 PF05160.13 OAG04725.1 - 0.057 13.5 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 DSS1/SEM1 family PQ-loop PF04193.14 OAG04725.1 - 1.4 8.7 5.5 17 5.3 0.1 3.4 3 1 0 3 3 3 0 PQ loop repeat p450 PF00067.22 OAG04726.1 - 2.5e-47 161.7 0.0 3.5e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GREB1 PF15782.5 OAG04728.1 - 2.7 5.0 13.0 3.3 4.7 13.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CAF1C_H4-bd PF12265.8 OAG04729.1 - 6.5e-25 87.2 0.1 1.7e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAG04729.1 - 1.8e-19 69.7 6.0 0.0031 18.3 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG04729.1 - 4.4e-05 23.7 0.0 0.11 12.8 0.1 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SPC22 PF04573.12 OAG04730.1 - 1.7e-37 128.6 0.3 7.5e-26 90.6 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit PBP PF01161.20 OAG04731.1 - 1.2e-15 58.0 0.0 1.6e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein NMO PF03060.15 OAG04733.1 - 6.9e-55 186.7 1.1 1.2e-53 182.7 1.1 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG04733.1 - 8.9e-13 47.9 0.0 2.8e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG04733.1 - 0.00033 19.8 1.4 0.00072 18.7 0.5 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DUF1902 PF08972.11 OAG04733.1 - 0.034 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) DUF1729 PF08354.10 OAG04733.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) 2-Hacid_dh_C PF02826.19 OAG04734.1 - 3.6e-41 140.5 0.0 5.8e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG04734.1 - 8.9e-12 44.8 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Vmethyltransf PF01660.17 OAG04734.1 - 0.0095 14.8 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Viral methyltransferase DUF374 PF04028.13 OAG04734.1 - 0.093 12.3 0.1 0.34 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF374) RmlD_sub_bind PF04321.17 OAG04736.1 - 2.4e-51 174.6 0.0 3.2e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OAG04736.1 - 2.3e-21 76.4 0.0 2.8e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG04736.1 - 4.3e-11 42.5 1.6 1.4e-09 37.5 0.3 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG04736.1 - 1.9e-10 40.7 0.2 4.8e-10 39.4 0.2 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG04736.1 - 2.8e-07 30.0 0.1 2.3e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 OAG04736.1 - 8.9e-07 28.2 0.1 2.3e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_16 PF13191.6 OAG04737.1 - 6e-07 30.0 0.1 1.5e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAG04737.1 - 5.6e-06 26.4 0.0 1.5e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG04737.1 - 0.0012 19.1 0.0 0.0026 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 OAG04737.1 - 0.0014 18.0 1.5 0.11 11.7 1.5 2.1 1 1 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.6 OAG04737.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG04737.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG04737.1 - 0.015 15.9 0.0 0.033 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG04737.1 - 0.016 15.7 0.0 0.03 14.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 OAG04737.1 - 0.019 14.9 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 OAG04737.1 - 0.022 15.1 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ploopntkinase3 PF18751.1 OAG04737.1 - 0.03 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 OAG04737.1 - 0.044 14.3 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAG04737.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OAG04737.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 OAG04737.1 - 0.13 12.4 0.2 0.26 11.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG04737.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF3433 PF11915.8 OAG04738.1 - 7.5e-39 132.1 13.7 7.6e-23 80.8 2.4 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) T_hemolysin PF12261.8 OAG04738.1 - 0.00053 19.8 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 Thermostable hemolysin DUF2207 PF09972.9 OAG04738.1 - 0.048 12.4 1.3 1.2 7.8 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) STAT6_C PF14596.6 OAG04739.1 - 0.15 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 STAT6 C-terminal Glyco_hydro_61 PF03443.14 OAG04740.1 - 1.1e-07 32.0 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 OAG04740.1 - 0.00054 20.7 0.0 0.001 19.8 0.0 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Metallophos PF00149.28 OAG04741.1 - 1.8e-37 129.8 0.1 3.8e-37 128.8 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NUDIX_2 PF13869.6 OAG04742.1 - 1e-79 266.5 0.0 1.2e-79 266.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase CoaE PF01121.20 OAG04743.1 - 2.1e-44 151.3 0.0 2.9e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 OAG04743.1 - 0.00091 19.4 0.0 0.0062 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG04743.1 - 0.054 14.0 0.1 0.79 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain AA_permease PF00324.21 OAG04746.1 - 3.6e-115 385.3 44.4 4.5e-115 385.0 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG04746.1 - 2.8e-28 98.9 50.9 3.7e-28 98.5 50.9 1.1 1 0 0 1 1 1 1 Amino acid permease Tad PF13400.6 OAG04747.1 - 0.019 15.3 0.9 0.042 14.2 0.9 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DIOX_N PF14226.6 OAG04748.1 - 2.9e-29 102.2 0.0 5e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG04748.1 - 3.5e-17 62.7 0.0 7e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_psq PF05225.16 OAG04748.1 - 0.14 11.9 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain GMC_oxred_N PF00732.19 OAG04749.1 - 1e-59 202.4 0.0 1.3e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG04749.1 - 7.5e-28 97.9 0.0 1.3e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG04749.1 - 2e-05 23.9 0.1 3.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG04749.1 - 3.5e-05 23.2 0.3 0.00077 18.8 0.1 2.7 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 OAG04749.1 - 0.00018 20.9 0.1 0.0013 18.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG04749.1 - 0.00028 21.1 0.1 0.0007 19.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG04749.1 - 0.00068 19.3 0.5 0.028 14.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG04749.1 - 0.0024 17.0 0.1 0.062 12.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 OAG04749.1 - 0.0065 15.8 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG04749.1 - 0.013 14.2 0.3 0.035 12.8 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAG04749.1 - 0.029 13.6 0.3 0.17 11.1 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG04749.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Glyco_hydro_1 PF00232.18 OAG04750.1 - 4.2e-104 348.5 0.2 5.9e-104 348.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 WD40 PF00400.32 OAG04750.1 - 4.3e-22 78.0 19.0 0.00016 22.4 0.1 7.8 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG04750.1 - 1.6e-15 57.2 3.5 0.00013 22.2 0.1 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG04750.1 - 0.00024 21.1 1.0 0.014 15.3 0.6 3.1 2 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A NAP PF00956.18 OAG04751.1 - 5e-25 88.2 11.9 5.7e-22 78.2 9.4 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Asparaginase PF00710.20 OAG04753.1 - 2.6e-51 173.9 0.0 4.7e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG04753.1 - 1.7e-26 92.7 0.1 3.5e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank PF00023.30 OAG04753.1 - 1e-07 32.0 0.9 0.00034 20.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAG04753.1 - 2.2e-07 31.4 0.1 6.8e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG04753.1 - 7.2e-07 29.4 0.1 1.9e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG04753.1 - 1e-06 29.2 0.0 5.2e-05 23.7 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG04753.1 - 0.00011 22.3 0.2 0.83 10.4 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeat NmrA PF05368.13 OAG04754.1 - 4.4e-70 235.9 0.0 5.3e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG04754.1 - 3.2e-07 30.4 0.0 4.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Ribosomal_L19 PF01245.20 OAG04755.1 - 2.6e-13 49.9 0.4 5.1e-13 48.9 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 DIRP PF06584.13 OAG04755.1 - 0.085 13.1 2.7 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 DIRP Pmp3 PF01679.17 OAG04756.1 - 2.8e-21 75.5 12.4 4.4e-21 74.8 12.4 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MmgE_PrpD PF03972.14 OAG04757.1 - 5.1e-118 394.4 4.4 5.8e-118 394.2 4.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family adh_short PF00106.25 OAG04758.1 - 6.6e-05 22.5 0.0 8.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Tannase PF07519.11 OAG04761.1 - 9e-95 318.3 0.1 1.1e-94 318.0 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 OAG04761.1 - 0.0012 18.1 0.0 0.0029 16.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG04761.1 - 0.0074 16.0 0.1 0.0074 16.0 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG04761.1 - 0.053 13.0 0.5 0.13 11.8 0.3 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family CAP PF00188.26 OAG04762.1 - 1.4e-17 64.7 0.7 2.5e-17 63.9 0.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PNPase_C PF12111.8 OAG04762.1 - 0.036 13.5 3.6 0.19 11.2 3.6 2.4 1 1 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal adh_short PF00106.25 OAG04763.1 - 2.2e-19 69.7 0.0 5e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04763.1 - 1.2e-09 38.1 0.0 1.4e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04763.1 - 5.5e-08 32.9 0.0 9.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 KR domain PA PF02225.22 OAG04763.1 - 0.031 14.3 0.0 0.8 9.8 0.0 2.2 2 0 0 2 2 2 0 PA domain Shikimate_DH PF01488.20 OAG04763.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDPD_2 PF13653.6 OAG04764.1 - 0.042 14.3 0.1 0.091 13.3 0.1 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family UPF0029 PF01205.19 OAG04765.1 - 6.2e-37 126.1 0.0 9.5e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 OAG04765.1 - 4.5e-06 26.9 0.0 1e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 RWD domain DUF1917 PF08939.10 OAG04765.1 - 0.024 14.6 0.4 0.033 14.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) UQ_con PF00179.26 OAG04765.1 - 0.033 13.8 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme Glyco_trans_1_2 PF13524.6 OAG04765.1 - 0.16 12.4 0.0 2.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 AT_hook PF02178.19 OAG04767.1 - 0.051 13.5 3.5 0.17 11.8 3.5 2.0 1 0 0 1 1 1 0 AT hook motif Fringe PF02434.16 OAG04768.1 - 5.1e-08 32.7 1.2 2.2e-06 27.3 1.2 2.7 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OAG04768.1 - 0.015 15.1 0.8 4.7 7.0 0.0 2.6 2 1 1 3 3 3 0 Galactosyltransferase RHH_3 PF12651.7 OAG04769.1 - 0.046 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain LRR_11 PF18831.1 OAG04770.1 - 0.0057 16.2 0.1 0.0098 15.4 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat Pkinase PF00069.25 OAG04771.1 - 4.6e-64 216.3 0.0 7.2e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04771.1 - 6.4e-43 146.9 0.0 2e-42 145.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG04771.1 - 4.2e-06 25.8 0.1 1.3e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAG04771.1 - 0.0089 15.4 0.0 0.073 12.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 OAG04771.1 - 0.028 14.6 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC1 family DUF4048 PF13257.6 OAG04772.1 - 3.2e-33 115.6 17.7 3.2e-33 115.6 17.7 4.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 OAG04772.1 - 0.09 12.8 2.5 0.27 11.3 2.5 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Tim17 PF02466.19 OAG04773.1 - 1.8e-41 141.0 5.7 2.6e-41 140.4 5.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TPPII_N PF12583.8 OAG04773.1 - 0.19 12.3 8.5 0.34 11.5 8.5 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal SSDP PF04503.13 OAG04773.1 - 0.29 11.4 15.8 0.35 11.1 15.8 1.1 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP NOB1_Zn_bind PF08772.11 OAG04775.1 - 6e-30 103.2 2.6 1e-29 102.5 2.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 OAG04775.1 - 1.1e-28 99.6 0.1 3.1e-28 98.1 0.1 1.8 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 OAG04775.1 - 0.0026 17.4 0.4 0.0026 17.4 0.4 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain DUF2321 PF10083.9 OAG04775.1 - 0.032 13.9 0.7 0.083 12.5 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) HypA PF01155.19 OAG04775.1 - 0.12 12.4 0.2 0.43 10.6 0.4 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 OAG04775.1 - 0.14 12.3 3.9 0.63 10.2 1.7 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 OAG04775.1 - 0.19 11.7 1.7 0.36 10.8 1.7 1.4 1 0 0 1 1 1 0 zinc-ribbons Rhodanese_C PF12368.8 OAG04775.1 - 0.27 11.6 2.0 0.52 10.7 2.0 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal WD40 PF00400.32 OAG04776.1 - 4.8e-27 93.7 10.1 0.00012 22.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG04776.1 - 0.00012 22.3 0.0 1.8 8.9 0.0 4.7 2 1 5 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 OAG04776.1 - 0.00071 19.4 0.1 2.9 8.0 0.0 4.4 4 0 0 4 4 4 1 PQQ enzyme repeat WD40_like PF17005.5 OAG04776.1 - 0.0046 16.3 0.1 0.04 13.2 0.1 2.2 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 OAG04776.1 - 0.036 12.7 0.1 0.16 10.6 0.0 2.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF5046 PF16465.5 OAG04776.1 - 0.066 12.6 1.1 2.1 7.7 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) Voldacs PF03517.13 OAG04777.1 - 4.4e-18 65.8 1.2 6.6e-18 65.2 0.1 2.0 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling PhoR PF11808.8 OAG04778.1 - 0.035 14.5 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Methyltransf_31 PF13847.6 OAG04781.1 - 6.8e-20 71.4 0.0 8.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG04781.1 - 6.5e-15 55.6 0.1 1.4e-14 54.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG04781.1 - 1.9e-14 53.5 0.0 4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG04781.1 - 1.4e-12 48.1 0.1 2.6e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG04781.1 - 1.5e-08 35.3 0.0 2.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG04781.1 - 7e-08 32.5 0.0 2.2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OAG04781.1 - 3.3e-06 27.0 0.0 5.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OAG04781.1 - 1.1e-05 24.9 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 OAG04781.1 - 3.2e-05 24.1 0.0 0.00067 19.8 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_3 PF01596.17 OAG04781.1 - 6.5e-05 22.2 0.1 0.00013 21.2 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 OAG04781.1 - 0.00061 19.4 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OAG04781.1 - 0.0014 18.0 0.1 0.0025 17.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OAG04781.1 - 0.0033 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAG04781.1 - 0.0091 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 GCD14 PF08704.10 OAG04781.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Met_10 PF02475.16 OAG04781.1 - 0.02 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.7 OAG04781.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Bombinin PF05298.11 OAG04781.1 - 0.037 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Bombinin N6_N4_Mtase PF01555.18 OAG04781.1 - 0.045 13.4 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 DNA methylase DOT1 PF08123.13 OAG04781.1 - 0.048 13.2 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.6 OAG04781.1 - 0.11 13.5 0.0 0.44 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain RIFIN PF02009.16 OAG04782.1 - 0.00036 20.5 0.1 0.0008 19.4 0.1 1.6 1 1 0 1 1 1 1 Rifin DUF4448 PF14610.6 OAG04782.1 - 0.002 18.0 0.1 0.0032 17.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Stevor PF17410.2 OAG04782.1 - 0.0095 15.5 0.3 0.038 13.5 0.0 1.9 1 1 1 2 2 2 1 Subtelomeric Variable Open Reading frame CFEM PF05730.11 OAG04782.1 - 0.019 15.1 5.8 0.035 14.2 5.8 1.6 1 1 0 1 1 1 0 CFEM domain DUF4381 PF14316.6 OAG04782.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3377 PF11857.8 OAG04782.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Collagen_mid PF15984.5 OAG04782.1 - 0.14 11.9 3.5 0.22 11.3 3.5 1.2 1 0 0 1 1 1 0 Bacterial collagen, middle region Phage_holin_3_6 PF07332.11 OAG04782.1 - 0.35 10.9 2.9 1.9 8.6 0.0 2.6 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SKG6 PF08693.10 OAG04782.1 - 2.3 7.7 6.0 4.7 6.7 6.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EthD PF07110.11 OAG04783.1 - 2.4e-10 41.4 0.3 3.2e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 EthD domain SQHop_cyclase_C PF13243.6 OAG04784.1 - 8.6e-49 166.3 6.4 5.3e-48 163.8 2.0 2.8 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OAG04784.1 - 7.2e-46 156.6 8.1 5.7e-39 133.9 1.0 3.9 2 1 2 4 4 4 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 OAG04784.1 - 9.2e-26 89.3 10.9 7.2e-08 32.0 0.0 5.2 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 OAG04784.1 - 7.7e-05 21.9 0.8 0.0057 15.7 0.2 3.1 1 1 2 3 3 3 1 A-macroglobulin TED domain Pec_lyase PF09492.10 OAG04784.1 - 0.003 16.9 1.4 8.7 5.6 0.0 4.6 2 1 1 4 4 4 1 Pectic acid lyase MAP65_ASE1 PF03999.12 OAG04785.1 - 1.1 7.8 2.6 1.4 7.5 2.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF1295 PF06966.12 OAG04787.1 - 1.3e-14 54.3 0.1 1.7e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OAG04787.1 - 1.2e-11 44.0 0.1 1.4e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 OAG04787.1 - 0.00049 20.1 0.1 0.00066 19.7 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DNA_ligase_A_M PF01068.21 OAG04788.1 - 7e-24 84.6 0.0 1.3e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAG04788.1 - 1.9e-15 57.6 0.0 3.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus mRNA_cap_enzyme PF01331.19 OAG04788.1 - 0.054 13.3 0.0 0.29 10.9 0.0 2.0 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Lipase_GDSL_2 PF13472.6 OAG04789.1 - 6.3e-22 78.8 0.5 9.4e-22 78.3 0.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG04789.1 - 1.1e-08 35.4 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase POTRA PF07244.15 OAG04789.1 - 0.13 12.9 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat CBFD_NFYB_HMF PF00808.23 OAG04790.1 - 9.8e-14 51.4 0.8 1.7e-13 50.6 0.8 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG04790.1 - 6.9e-05 23.2 0.3 0.00024 21.5 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Acyltransferase PF01553.21 OAG04791.1 - 6.9e-14 51.6 0.0 1.6e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase zf-NOSIP PF15906.5 OAG04792.1 - 3.3e-07 30.3 0.0 1.1e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 OAG04792.1 - 1.7e-05 24.5 19.0 0.0033 17.2 7.7 3.5 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG04792.1 - 7.4e-05 22.7 11.9 0.00015 21.7 3.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG04792.1 - 8.9e-05 22.4 6.6 8.9e-05 22.4 6.6 3.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG04792.1 - 0.00014 21.6 3.0 0.00014 21.6 3.0 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG04792.1 - 0.00023 21.4 19.3 0.00033 20.9 6.2 2.9 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 OAG04792.1 - 0.00066 19.5 2.2 0.00066 19.5 2.2 3.0 4 0 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) BIR PF00653.21 OAG04792.1 - 0.018 15.7 0.6 9.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Prok-RING_4 PF14447.6 OAG04792.1 - 0.1 12.5 20.4 0.15 11.9 7.9 3.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-H2C2_2 PF13465.6 OAG04792.1 - 0.2 12.2 0.4 0.2 12.2 0.4 3.7 3 0 0 3 3 3 0 Zinc-finger double domain FYVE PF01363.21 OAG04792.1 - 0.31 11.2 10.9 1.1 9.4 5.4 2.8 2 1 0 2 2 2 0 FYVE zinc finger Rtf2 PF04641.12 OAG04792.1 - 8.8 5.6 21.5 0.12 11.7 6.7 3.2 2 2 1 3 3 3 0 Rtf2 RING-finger zinc-ribbons_6 PF07191.12 OAG04792.1 - 8.9 6.4 11.5 33 4.6 2.9 3.3 2 1 0 2 2 2 0 zinc-ribbons ABC2_membrane PF01061.24 OAG04793.1 - 6.3e-08 32.3 0.5 8e-08 31.9 0.5 1.1 1 0 0 1 1 1 1 ABC-2 type transporter tRNA-synt_1e PF01406.19 OAG04795.1 - 4.6e-115 384.1 0.0 7.6e-115 383.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OAG04795.1 - 2.3e-05 23.3 0.2 0.05 12.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 OAG04795.1 - 0.021 15.3 0.2 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 DALR domain GCD14 PF08704.10 OAG04796.1 - 4.2e-62 210.0 1.8 3.4e-22 79.3 0.0 4.1 3 1 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 OAG04796.1 - 0.039 13.0 0.0 0.095 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3586 PF12131.8 OAG04796.1 - 0.34 11.1 3.6 0.91 9.8 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) PhoD PF09423.10 OAG04797.1 - 1.4e-42 146.0 0.0 5.6e-42 144.0 0.0 2.0 2 1 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.21 OAG04797.1 - 0.015 15.6 0.4 0.073 13.4 0.1 2.3 2 0 0 2 2 2 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OAG04797.1 - 0.036 14.6 0.1 0.077 13.6 0.1 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 OAG04797.1 - 0.038 14.5 1.5 0.081 13.4 1.5 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase MFS_1 PF07690.16 OAG04799.1 - 2.2e-25 89.3 61.1 1.4e-24 86.7 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CRPA PF05745.11 OAG04799.1 - 0.84 9.6 4.3 16 5.5 0.4 3.2 2 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4131 PF13567.6 OAG04799.1 - 7.8 6.1 13.9 3.1 7.4 1.9 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Podoplanin PF05808.11 OAG04800.1 - 0.035 14.2 0.2 0.063 13.4 0.2 1.4 1 0 0 1 1 1 0 Podoplanin DUF2076 PF09849.9 OAG04801.1 - 0.0032 17.5 1.1 0.004 17.2 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Nop10p PF04135.12 OAG04802.1 - 3e-20 72.0 0.2 3.8e-20 71.7 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family ACT_7 PF13840.6 OAG04805.1 - 2.4e-27 94.5 0.0 1.5e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 ACT domain Spo0M PF07070.11 OAG04805.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein CorA PF01544.18 OAG04806.1 - 0.005 16.2 0.2 0.005 16.2 0.2 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein adh_short PF00106.25 OAG04809.1 - 1.6e-35 122.4 0.0 3.3e-35 121.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04809.1 - 9e-26 90.9 0.0 1.5e-25 90.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04809.1 - 1.2e-10 41.6 0.0 1.9e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG04809.1 - 2.2e-06 27.3 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG04809.1 - 0.0019 18.1 0.1 0.0023 17.8 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding MTS PF05175.14 OAG04809.1 - 0.0043 16.6 0.3 0.072 12.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase small domain GDP_Man_Dehyd PF16363.5 OAG04809.1 - 0.0056 16.1 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG04809.1 - 0.016 14.3 0.0 0.045 12.9 0.0 1.8 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG04809.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.23 OAG04809.1 - 0.057 13.5 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Spidroin_MaSp PF11260.8 OAG04809.1 - 0.21 11.9 1.5 2.4 8.5 0.2 2.7 2 1 1 3 3 3 0 Major ampullate spidroin 1 and 2 HET PF06985.11 OAG04810.1 - 5.3e-32 111.2 2.0 1.5e-31 109.7 2.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 OAG04811.1 - 2.4e-50 171.3 1.8 2.7e-50 171.1 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG04811.1 - 1.2e-41 142.3 1.6 1.4e-41 142.1 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG04811.1 - 1.5e-09 38.1 0.0 2.1e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG04811.1 - 4.5e-06 26.3 0.0 3.2e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG04811.1 - 0.0016 17.6 0.1 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 OAG04811.1 - 0.0071 16.9 0.1 0.11 13.1 0.1 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 OAG04811.1 - 0.012 15.0 0.0 0.033 13.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 OAG04811.1 - 0.023 14.5 0.1 0.067 13.0 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein GFO_IDH_MocA PF01408.22 OAG04812.1 - 2.2e-17 64.0 0.5 3.4e-17 63.4 0.5 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG04812.1 - 0.0026 18.4 0.1 0.0044 17.7 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Exo_endo_phos PF03372.23 OAG04813.1 - 1e-13 51.4 0.1 1.9e-13 50.5 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OAG04813.1 - 0.0025 17.6 0.2 0.077 12.8 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase MFS_1 PF07690.16 OAG04814.1 - 1.8e-11 43.6 32.8 1.8e-11 43.6 32.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04816.1 - 3.5e-88 296.4 23.6 4.3e-88 296.1 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG04816.1 - 1.5e-18 66.9 50.5 1.2e-16 60.7 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 OAG04816.1 - 0.66 9.8 6.2 0.86 9.4 0.1 2.3 2 0 0 2 2 2 0 VIT family Treacle PF03546.14 OAG04817.1 - 0.042 12.7 0.1 0.05 12.4 0.1 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle Zn_clus PF00172.18 OAG04818.1 - 1.9e-08 34.3 9.0 4.2e-08 33.2 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_7 PF00840.20 OAG04819.1 - 4.5e-187 622.1 15.7 5.1e-187 621.9 15.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 F-box-like PF12937.7 OAG04822.1 - 1.6e-05 24.7 0.4 5.6e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 OAG04822.1 - 0.2 11.5 0.1 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 F-box DUF1996 PF09362.10 OAG04823.1 - 9.5e-44 150.1 0.1 1.4e-43 149.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TauD PF02668.16 OAG04824.1 - 2.3e-62 211.2 0.4 2.9e-62 210.9 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.19 OAG04825.1 - 3.4e-30 105.0 0.0 7.5e-17 60.9 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG04825.1 - 4.9e-19 68.7 0.1 1.8e-14 53.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG04825.1 - 1.5e-12 47.4 0.1 3.8e-12 46.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG04825.1 - 6e-10 39.2 3.1 0.00013 21.7 1.7 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG04825.1 - 6.7e-09 35.9 0.0 3.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG04825.1 - 5.3e-07 29.7 1.3 6.4e-05 23.0 1.6 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG04825.1 - 0.00012 21.5 0.6 0.017 14.4 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 OAG04825.1 - 0.00017 20.8 0.7 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG04825.1 - 0.00026 21.5 3.0 0.00068 20.1 0.3 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG04825.1 - 0.0011 18.1 2.1 0.0018 17.4 0.3 2.0 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 OAG04825.1 - 0.0027 16.5 1.4 0.01 14.6 0.5 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OAG04825.1 - 0.0041 16.4 0.2 0.0097 15.2 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.20 OAG04825.1 - 0.0079 16.3 0.0 0.098 12.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OAG04825.1 - 0.054 13.1 0.9 0.72 9.5 0.2 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 OAG04825.1 - 0.08 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG04825.1 - 0.094 12.0 1.0 0.16 11.3 0.4 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 OAG04825.1 - 0.097 12.2 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_3 PF01494.19 OAG04825.1 - 0.12 11.6 0.3 0.25 10.6 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain DUF1367 PF07105.11 OAG04825.1 - 0.16 11.7 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) GIDA PF01134.22 OAG04825.1 - 0.84 8.6 3.1 0.42 9.6 1.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 OAG04826.1 - 1.8e-37 129.1 9.7 2.7e-37 128.5 8.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG04826.1 - 8.3e-06 25.3 0.5 8.3e-06 25.3 0.5 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Nucleoporin_FG PF13634.6 OAG04827.1 - 1.7e-05 25.5 10.4 0.00025 21.8 10.4 2.4 1 1 0 1 1 1 1 Nucleoporin FG repeat region zf-CHCC PF10276.9 OAG04828.1 - 2.3e-16 59.5 2.1 4.5e-16 58.6 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger domain SNAP-25 PF00835.19 OAG04828.1 - 0.71 10.2 3.1 0.93 9.8 0.2 2.6 3 1 0 3 3 3 0 SNAP-25 family ALMT PF11744.8 OAG04829.1 - 0.029 13.2 1.7 0.048 12.5 1.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter GP38 PF05268.11 OAG04829.1 - 0.1 12.2 0.4 0.17 11.5 0.4 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Peptidase_M16_M PF16187.5 OAG04830.1 - 5.9e-97 324.3 1.3 1.3e-96 323.2 1.3 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 OAG04830.1 - 6.6e-34 117.5 0.0 6.5e-22 78.4 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG04830.1 - 2.2e-32 112.1 2.5 8.1e-32 110.3 1.3 2.6 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) EthD PF07110.11 OAG04831.1 - 1e-18 68.3 0.4 1.3e-18 67.9 0.4 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG04831.1 - 0.00058 20.3 0.3 0.00081 19.8 0.3 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Benyvirus_P25 PF05744.11 OAG04831.1 - 0.011 15.0 0.2 0.014 14.7 0.2 1.1 1 0 0 1 1 1 0 Benyvirus P25/P26 protein zf-CCHC PF00098.23 OAG04832.1 - 0.00037 20.4 1.2 0.00057 19.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle MPP6 PF10175.9 OAG04832.1 - 0.0032 18.0 4.4 0.77 10.3 0.7 2.8 2 1 1 3 3 3 2 M-phase phosphoprotein 6 Serglycin PF04360.12 OAG04832.1 - 0.015 15.3 5.5 0.023 14.6 5.3 1.5 1 1 0 1 1 1 0 Serglycin Cwf_Cwc_15 PF04889.12 OAG04832.1 - 0.045 13.5 2.8 0.064 13.0 2.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CCHC_4 PF14392.6 OAG04832.1 - 0.067 12.9 0.5 0.17 11.7 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 OAG04832.1 - 0.088 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger Glyco_hydro_127 PF07944.12 OAG04832.1 - 0.14 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 TFIIF_alpha PF05793.12 OAG04832.1 - 0.91 8.0 14.9 0.14 10.8 6.2 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SEEEED PF14797.6 OAG04832.1 - 3.8 7.7 14.5 0.17 12.0 6.4 2.1 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex FLILHELTA PF10306.9 OAG04833.1 - 1.6e-32 111.8 0.1 2.9e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 OAG04833.1 - 0.0042 17.6 0.0 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2079 PF09852.9 OAG04833.1 - 0.053 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) UPF0047 PF01894.17 OAG04835.1 - 1.9e-38 131.1 0.0 2.6e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans_2 PF11951.8 OAG04837.1 - 4.3e-48 164.1 1.8 2.7e-47 161.4 1.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG04837.1 - 7e-07 29.3 9.2 1.1e-06 28.7 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 OAG04838.1 - 9.1e-69 232.3 0.0 1.3e-68 231.8 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Ribosomal_L27 PF01016.19 OAG04839.1 - 4e-29 100.4 0.1 4e-29 100.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal L27 protein STE2 PF02116.15 OAG04840.1 - 0.022 14.1 0.3 0.022 14.1 0.3 1.8 1 1 1 2 2 2 0 Fungal pheromone mating factor STE2 GPCR MWFE PF15879.5 OAG04840.1 - 0.43 10.8 2.8 4.8 7.4 0.0 3.4 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF2231 PF09990.9 OAG04840.1 - 0.52 10.8 9.7 1.4 9.4 0.9 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) ATP-synt_ab PF00006.25 OAG04841.1 - 3.5e-110 366.7 0.0 4.8e-110 366.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OAG04841.1 - 2.9e-46 156.3 0.0 6.9e-46 155.1 0.0 1.7 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OAG04841.1 - 1e-14 54.8 3.1 2e-14 53.8 3.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Dynamin_M PF01031.20 OAG04842.1 - 2.2e-101 338.9 0.0 4.2e-101 337.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OAG04842.1 - 4.9e-57 192.6 0.1 1.1e-56 191.5 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OAG04842.1 - 4.7e-30 103.6 5.4 1.1e-29 102.4 5.4 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAG04842.1 - 1.5e-05 25.1 0.4 5.5e-05 23.2 0.4 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG04842.1 - 0.12 11.9 0.3 18 4.8 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B adh_short PF00106.25 OAG04844.1 - 7e-36 123.5 0.1 9.4e-36 123.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04844.1 - 1.4e-26 93.5 0.0 1.9e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04844.1 - 5.9e-08 32.8 0.1 1.8e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG04844.1 - 0.00022 20.5 0.1 0.00029 20.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG04844.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF723 PF05265.13 OAG04844.1 - 0.17 11.9 0.1 0.58 10.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF723) Zn_clus PF00172.18 OAG04845.1 - 1.4e-05 25.1 11.4 2.7e-05 24.2 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 OAG04846.1 - 8e-73 245.1 0.0 1.8e-72 243.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OAG04846.1 - 1.3e-61 207.7 2.9 1.7e-61 207.2 0.7 2.5 3 0 0 3 3 2 1 KR domain Acyl_transf_1 PF00698.21 OAG04846.1 - 1.7e-47 162.5 0.0 3.3e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG04846.1 - 4.6e-43 147.6 0.0 8.5e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 OAG04846.1 - 9e-41 138.6 0.0 3.7e-40 136.6 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAG04846.1 - 3.2e-18 66.2 0.0 8.5e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OAG04846.1 - 5e-18 65.3 1.7 6.7e-17 61.6 0.5 2.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04846.1 - 1.2e-09 38.1 1.3 1.2e-09 38.1 1.3 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 OAG04846.1 - 2.4e-08 34.0 0.2 7.2e-08 32.5 0.2 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 OAG04846.1 - 1.5e-06 28.4 0.1 3.5e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 OAG04846.1 - 4.2e-06 27.8 0.2 2.5e-05 25.3 0.1 2.5 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG04846.1 - 4.7e-05 23.2 0.4 0.00016 21.6 0.4 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 OAG04846.1 - 8.9e-05 22.0 0.3 0.00024 20.6 0.3 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.13 OAG04846.1 - 0.011 15.3 0.8 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.15 OAG04846.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 OAG04846.1 - 0.1 12.4 0.4 0.44 10.4 0.4 2.2 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FSH1 PF03959.13 OAG04847.1 - 7.6e-30 104.2 0.0 4.1e-29 101.8 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.11 OAG04847.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain ABC_membrane PF00664.23 OAG04848.1 - 1.5e-75 254.4 31.8 4.9e-46 157.6 16.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG04848.1 - 1.1e-62 210.5 0.0 3.4e-31 108.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG04848.1 - 3.2e-16 59.4 3.3 1.2e-06 28.1 0.9 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG04848.1 - 7.5e-09 36.0 0.5 0.0054 17.0 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG04848.1 - 1e-07 31.6 1.4 0.0043 16.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG04848.1 - 2.9e-07 31.0 1.2 0.023 15.1 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG04848.1 - 6.8e-07 29.3 0.0 0.044 13.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 OAG04848.1 - 7.4e-07 28.3 0.4 0.024 13.5 0.0 3.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 OAG04848.1 - 1.2e-06 28.6 0.2 0.38 10.5 0.0 3.8 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OAG04848.1 - 2.4e-06 27.4 0.4 0.024 14.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 OAG04848.1 - 3.6e-05 24.0 0.1 0.064 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OAG04848.1 - 6.3e-05 22.8 0.0 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAG04848.1 - 7.8e-05 23.3 1.0 0.51 10.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.17 OAG04848.1 - 0.00015 21.7 0.1 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 OAG04848.1 - 0.00027 20.8 0.0 0.39 10.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 OAG04848.1 - 0.00032 21.3 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAG04848.1 - 0.00032 20.3 0.7 0.39 10.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 OAG04848.1 - 0.00061 19.3 0.0 0.91 9.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region SRP54 PF00448.22 OAG04848.1 - 0.00062 19.5 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 OAG04848.1 - 0.00068 19.6 0.1 1.9 8.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 OAG04848.1 - 0.0011 19.4 2.7 1.4 9.3 0.2 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OAG04848.1 - 0.0029 17.4 1.2 0.72 9.6 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 OAG04848.1 - 0.0058 16.4 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 OAG04848.1 - 0.0065 16.4 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 OAG04848.1 - 0.0069 16.6 0.1 4.3 7.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OAG04848.1 - 0.0099 16.1 4.5 1 9.6 0.7 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 OAG04848.1 - 0.019 15.1 0.1 0.79 9.8 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 OAG04848.1 - 0.034 14.1 0.0 2.6 7.9 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 OAG04848.1 - 0.036 13.4 0.2 3.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin APS_kinase PF01583.20 OAG04848.1 - 0.042 13.8 0.0 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 OAG04848.1 - 0.066 13.6 0.0 17 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF3987 PF13148.6 OAG04848.1 - 0.07 12.1 0.0 2.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Synapsin_N PF10581.9 OAG04848.1 - 0.072 13.1 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Synapsin N-terminal AAA_17 PF13207.6 OAG04848.1 - 0.078 13.4 0.2 19 5.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.20 OAG04848.1 - 0.17 11.0 0.0 8.4 5.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 OAG04848.1 - 0.69 9.8 3.5 88 2.9 0.0 3.7 4 0 0 4 4 4 0 NTPase Beta-lactamase PF00144.24 OAG04849.1 - 7.3e-32 110.9 0.7 7.3e-32 110.9 0.7 2.0 2 0 0 2 2 2 2 Beta-lactamase Glyoxalase_4 PF13669.6 OAG04850.1 - 0.035 14.4 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DHDPS PF00701.22 OAG04851.1 - 1.5e-39 135.4 0.0 1.8e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family NRBF2_MIT PF17169.4 OAG04851.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 BNR_4 PF15892.5 OAG04854.1 - 5.8e-68 229.2 4.0 8.3e-68 228.7 4.0 1.2 1 0 0 1 1 1 1 BNR repeat-containing family member BNR_2 PF13088.6 OAG04854.1 - 0.058 12.7 0.3 0.16 11.3 0.3 1.7 1 1 0 1 1 1 0 BNR repeat-like domain p450 PF00067.22 OAG04855.1 - 1.1e-74 251.8 0.0 1.4e-74 251.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.21 OAG04856.1 - 3.6e-92 309.5 42.6 4.2e-92 309.2 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG04856.1 - 7.2e-24 84.4 49.3 9.7e-24 84.0 49.3 1.1 1 0 0 1 1 1 1 Amino acid permease Tyrosinase PF00264.20 OAG04857.1 - 1.8e-35 123.3 3.2 2.6e-35 122.7 3.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 OAG04859.1 - 9.6e-28 97.1 29.9 2.7e-22 79.2 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04859.1 - 7.2e-11 41.6 1.9 7.2e-11 41.6 1.9 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter FAD_binding_4 PF01565.23 OAG04860.1 - 9.7e-24 83.7 0.1 1.8e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG04860.1 - 0.0065 16.5 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FUSC PF04632.12 OAG04861.1 - 3.2 6.2 19.5 0.025 13.2 7.2 2.3 1 1 2 3 3 3 0 Fusaric acid resistance protein family LSM PF01423.22 OAG04862.1 - 2.1e-08 33.7 0.0 2.6e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG04862.1 - 0.0017 18.5 0.0 0.0019 18.3 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain adh_short PF00106.25 OAG04863.1 - 6.9e-49 166.0 0.0 8.6e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04863.1 - 1e-33 116.8 0.0 1.3e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04863.1 - 2.2e-12 47.3 0.0 3.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG04863.1 - 0.023 14.9 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 OAG04863.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 OAG04863.1 - 0.081 12.0 0.1 0.13 11.3 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RNA_binding PF01877.17 OAG04863.1 - 0.082 13.2 0.0 8.8 6.6 0.0 2.2 2 0 0 2 2 2 0 RNA binding CDH-cyt PF16010.5 OAG04864.1 - 1.2e-44 152.1 3.7 2.5e-44 151.2 3.7 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 OAG04864.1 - 2.8e-29 102.5 0.0 6.5e-29 101.2 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG04864.1 - 2e-20 73.8 0.2 3.9e-20 72.9 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG04864.1 - 5.8e-08 32.2 0.0 9.3e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 OAG04864.1 - 2.3e-05 24.9 0.0 0.072 13.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG04864.1 - 0.00012 22.2 0.0 0.00047 20.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG04864.1 - 0.00017 21.3 0.0 0.092 12.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG04864.1 - 0.00038 19.8 0.0 0.0017 17.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG04864.1 - 0.00049 18.9 0.1 0.0018 17.1 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein DOMON PF03351.17 OAG04864.1 - 0.004 17.4 0.1 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 DOMON domain FAD_oxidored PF12831.7 OAG04864.1 - 0.0054 16.1 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG04864.1 - 0.0091 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG04864.1 - 0.013 14.7 0.1 0.37 10.0 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 OAG04864.1 - 0.015 14.6 0.3 0.067 12.4 0.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG04864.1 - 0.049 12.9 0.2 0.083 12.1 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 OAG04864.1 - 0.098 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 OAG04864.1 - 0.2 10.7 0.1 0.89 8.6 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Fimbrial_PilY2 PF14481.6 OAG04865.1 - 0.11 12.2 0.2 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 Septin PF00735.18 OAG04866.1 - 7.6e-112 373.2 0.5 1.1e-111 372.7 0.5 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAG04866.1 - 3.6e-07 30.3 0.0 7.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG04866.1 - 3.7e-06 26.6 2.8 5.2e-05 22.9 0.2 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG04866.1 - 4.1e-06 26.8 0.1 3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAG04866.1 - 0.0012 19.1 0.3 0.0054 17.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 OAG04866.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 OAG04866.1 - 0.0047 17.1 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 OAG04866.1 - 0.0089 15.1 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FOXP-CC PF16159.5 OAG04866.1 - 0.0096 16.5 1.2 0.034 14.8 1.2 2.0 1 0 0 1 1 1 1 FOXP coiled-coil domain AAA_24 PF13479.6 OAG04866.1 - 0.018 14.8 0.4 0.036 13.8 0.4 1.6 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 OAG04866.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 OAG04866.1 - 0.019 15.4 0.1 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 OAG04866.1 - 0.024 13.9 0.0 0.041 13.1 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 OAG04866.1 - 0.028 13.5 0.4 0.088 11.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 OAG04866.1 - 0.035 14.6 0.1 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Ras PF00071.22 OAG04866.1 - 0.047 13.3 0.8 0.15 11.7 0.4 2.0 2 1 0 2 2 2 0 Ras family NACHT PF05729.12 OAG04866.1 - 0.051 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 OAG04866.1 - 0.064 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 OAG04866.1 - 0.075 12.8 0.3 3.1 7.6 0.3 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 OAG04866.1 - 0.093 12.3 0.0 0.26 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG04866.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 OAG04866.1 - 0.19 11.5 1.2 13 5.5 0.1 2.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 OAG04866.1 - 0.52 10.3 6.4 3.5 7.7 0.1 3.2 2 1 1 3 3 3 0 Dynamin family DUF1043 PF06295.12 OAG04866.1 - 0.79 9.7 5.0 0.27 11.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) AAA_11 PF13086.6 OAG04866.1 - 6.8 6.4 6.8 20 4.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 OAG04867.1 - 1.1e-42 143.1 20.7 5.8e-10 39.6 0.0 12.4 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.12 OAG04867.1 - 7.3e-25 87.3 0.1 1.1e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAG04867.1 - 4.1e-21 75.1 0.0 0.017 15.4 0.0 10.5 4 2 4 10 10 10 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG04867.1 - 4.1e-11 42.4 0.5 0.11 11.5 0.0 6.2 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG04867.1 - 1.7e-07 31.3 0.4 0.0019 18.1 0.1 4.8 6 0 0 6 6 6 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAG04867.1 - 8.6e-06 24.7 5.1 1.8 7.1 0.0 4.7 3 2 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG04867.1 - 0.00018 21.0 0.0 1.3 8.3 0.0 3.5 3 0 0 3 3 3 1 WD40-like domain Nbas_N PF15492.6 OAG04867.1 - 0.00049 19.5 0.3 14 4.9 0.0 4.4 3 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 OAG04867.1 - 0.034 14.1 0.0 6.8 6.8 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 OAG04867.1 - 0.053 12.6 0.7 6.4 5.8 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1513) RPN1_RPN2_N PF17781.1 OAG04867.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain PTRF_SDPR PF15237.6 OAG04867.1 - 0.13 11.9 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 PTRF/SDPR family PQQ_3 PF13570.6 OAG04867.1 - 5.6 7.6 8.3 51 4.5 0.0 5.6 7 0 0 7 7 7 0 PQQ-like domain Egh16-like PF11327.8 OAG04868.1 - 1.6e-49 168.8 10.6 1.6e-49 168.8 10.6 2.5 2 1 0 2 2 2 1 Egh16-like virulence factor Izumo-Ig PF16706.5 OAG04868.1 - 0.0022 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain I-set PF07679.16 OAG04868.1 - 0.017 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain PSI PF01437.25 OAG04869.1 - 3.4e-05 24.3 6.2 6.7e-05 23.4 6.2 1.5 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 OAG04869.1 - 0.024 14.4 5.1 0.04 13.7 5.1 1.3 1 0 0 1 1 1 0 Integrin plexin domain Gemini_mov PF01708.16 OAG04869.1 - 0.046 13.5 0.3 0.079 12.7 0.3 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein WAK_assoc PF14380.6 OAG04869.1 - 0.06 14.1 3.1 0.092 13.5 3.1 1.3 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal Actin_micro PF17003.5 OAG04870.1 - 0.18 11.0 0.3 0.25 10.5 0.3 1.2 1 0 0 1 1 1 0 Putative actin-like family TGT PF01702.18 OAG04872.1 - 4e-56 190.7 0.0 5.1e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Sugar_tr PF00083.24 OAG04873.1 - 9.1e-77 258.8 19.5 1.1e-76 258.5 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG04873.1 - 3e-17 62.6 18.1 5.2e-17 61.8 18.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3328 PF11807.8 OAG04874.1 - 8.9e-45 153.1 0.7 1e-44 152.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pkinase_fungal PF17667.1 OAG04875.1 - 3.9e-131 437.6 0.0 4.7e-131 437.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG04876.1 - 3.7e-05 23.8 0.0 0.002 18.1 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG04876.1 - 0.00026 20.7 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 OAG04876.1 - 0.12 11.7 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 OAG04876.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5379 PF17350.2 OAG04880.1 - 0.023 15.0 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5379) DUF4499 PF14934.6 OAG04880.1 - 0.13 12.6 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4499) Peptidase_S9 PF00326.21 OAG04881.1 - 0.0036 16.8 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OAG04881.1 - 0.06 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Herpes_US12 PF05363.12 OAG04883.1 - 0.076 13.8 0.1 0.17 12.6 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus US12 family TPR_12 PF13424.6 OAG04884.1 - 6.1e-12 45.7 0.7 3e-08 33.9 0.5 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG04884.1 - 3.1e-11 42.8 6.4 8e-05 22.4 1.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG04884.1 - 3.2e-06 26.5 0.0 1.4e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 OAG04884.1 - 0.00024 21.1 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG04884.1 - 0.048 14.0 5.2 0.12 12.8 0.7 3.4 2 2 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 OAG04884.1 - 0.068 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain An_peroxidase PF03098.15 OAG04885.1 - 0.03 12.9 0.0 0.048 12.2 0.0 1.3 2 0 0 2 2 2 0 Animal haem peroxidase PNP_UDP_1 PF01048.20 OAG04886.1 - 9.5e-08 31.6 1.7 3.4e-07 29.8 1.7 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_10 PF13374.6 OAG04887.1 - 2.1e-16 59.2 0.1 0.00013 21.7 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG04887.1 - 3.6e-14 52.8 0.2 3.6e-06 27.2 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat NACHT PF05729.12 OAG04887.1 - 5.6e-06 26.4 0.1 1.4e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 OAG04887.1 - 0.00011 21.5 0.1 0.028 13.6 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 OAG04887.1 - 0.0023 17.5 0.2 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 OAG04887.1 - 0.0084 16.1 0.1 0.088 12.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG04887.1 - 0.099 12.8 0.5 10 6.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Helo_like_N PF17111.5 OAG04888.1 - 3.2e-21 75.7 4.4 4.2e-21 75.3 3.6 1.6 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins Ureide_permease PF07168.11 OAG04888.1 - 0.12 11.1 1.9 0.19 10.5 1.9 1.2 1 0 0 1 1 1 0 Ureide permease CAMSAP_CC1 PF17095.5 OAG04888.1 - 0.37 10.7 6.3 0.062 13.2 1.7 2.0 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Vps51 PF08700.11 OAG04888.1 - 3.1 8.0 9.1 11 6.2 1.2 3.8 4 0 0 4 4 4 0 Vps51/Vps67 TPR_12 PF13424.6 OAG04890.1 - 1.4e-15 57.3 0.8 1.1e-06 28.8 0.0 4.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAG04890.1 - 6e-12 45.0 10.1 5.5e-05 22.9 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat NACHT PF05729.12 OAG04890.1 - 9e-08 32.2 0.3 1.9e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 OAG04890.1 - 6e-07 28.9 0.0 0.0021 17.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_7 PF13176.6 OAG04890.1 - 0.015 15.2 0.1 2.7 8.2 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_16 PF13191.6 OAG04890.1 - 0.022 15.2 2.6 0.16 12.3 0.9 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 OAG04890.1 - 0.029 14.0 1.2 0.16 11.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain BSD PF03909.17 OAG04892.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 BSD domain Abhydrolase_1 PF00561.20 OAG04893.1 - 0.0037 16.9 0.3 0.44 10.1 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ribosomal_L16 PF00252.18 OAG04894.1 - 9.6e-31 106.5 0.1 1.9e-30 105.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 OAG04895.1 - 3.3e-58 196.3 0.0 4.5e-57 192.6 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 OAG04895.1 - 1.1e-15 57.8 0.0 3.5e-15 56.1 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 OAG04895.1 - 1.4e-10 41.7 0.1 4.6e-10 40.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG04895.1 - 2.1e-06 27.8 0.0 6.1e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OAG04895.1 - 0.00048 20.5 0.9 0.0022 18.4 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAG04895.1 - 0.0011 19.2 0.2 0.0052 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain PTCB-BRCT PF12738.7 OAG04895.1 - 0.0033 17.3 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain RuvB_N PF05496.12 OAG04895.1 - 0.0041 16.9 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAG04895.1 - 0.0052 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG04895.1 - 0.016 15.5 0.0 0.069 13.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAG04895.1 - 0.026 14.6 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG04895.1 - 0.054 14.0 0.1 0.27 11.8 0.1 2.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG04895.1 - 0.076 12.9 0.0 0.75 9.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 OAG04895.1 - 0.16 11.9 1.5 1.2 9.1 0.0 2.6 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 OAG04895.1 - 0.5 10.6 0.0 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 OAG04896.1 - 1.1e-09 38.6 0.0 1.5e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG04896.1 - 3.2e-09 36.8 0.0 5.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG04896.1 - 8e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 OAG04896.1 - 0.003 17.7 0.4 0.015 15.5 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG04896.1 - 0.042 13.9 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG04896.1 - 0.16 11.9 0.0 0.59 10.1 0.0 2.0 2 1 0 2 2 2 0 FR47-like protein GDI PF00996.18 OAG04897.1 - 2.6e-22 79.0 0.0 4.7e-21 74.8 0.0 2.1 1 1 0 1 1 1 1 GDP dissociation inhibitor SMC_N PF02463.19 OAG04898.1 - 6.7e-24 84.5 0.0 2.1e-23 82.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG04898.1 - 9.2e-20 72.0 0.0 9.2e-20 72.0 0.0 5.1 2 2 2 4 4 1 1 AAA domain AAA_15 PF13175.6 OAG04898.1 - 1.1e-06 28.7 18.5 9.6e-05 22.3 8.7 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAG04898.1 - 1.8e-05 24.4 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG04898.1 - 0.00051 19.9 10.6 0.013 15.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 OAG04898.1 - 0.0031 17.8 0.0 0.023 15.0 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_27 PF13514.6 OAG04898.1 - 0.017 14.7 0.0 0.017 14.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 OAG04898.1 - 0.045 14.3 0.4 0.045 14.3 0.4 4.9 4 3 0 4 4 3 0 ABC transporter AAA_25 PF13481.6 OAG04898.1 - 0.07 12.7 0.8 0.47 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAG04898.1 - 0.13 12.2 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 OAG04898.1 - 0.24 11.7 3.2 11 6.3 0.2 3.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG04898.1 - 0.28 11.6 1.8 0.83 10.1 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG04898.1 - 5 7.5 0.0 5 7.5 0.0 3.9 3 1 0 3 3 2 0 AAA ATPase domain Lyase_1 PF00206.20 OAG04899.1 - 1e-113 379.9 0.0 1.4e-113 379.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OAG04899.1 - 1.8e-20 73.1 0.1 4.5e-20 71.8 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus zf-RING_2 PF13639.6 OAG04900.1 - 2.2e-08 34.3 9.6 4.8e-08 33.2 9.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG04900.1 - 4.5e-07 29.8 2.6 8.5e-07 28.9 2.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG04900.1 - 3.4e-06 27.2 10.8 6.4e-06 26.4 10.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG04900.1 - 1.5e-05 24.9 7.5 3.1e-05 23.9 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG04900.1 - 2.9e-05 23.8 10.7 5.2e-05 23.0 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG04900.1 - 0.00078 19.4 9.7 0.0016 18.4 9.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Pellino PF04710.14 OAG04900.1 - 0.012 14.4 0.6 0.016 13.9 0.6 1.1 1 0 0 1 1 1 0 Pellino Prok-RING_4 PF14447.6 OAG04900.1 - 0.019 14.8 9.3 0.11 12.4 9.4 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG04900.1 - 0.12 12.2 10.8 0.38 10.6 10.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG04900.1 - 0.21 11.4 3.0 0.61 9.9 3.0 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 OAG04900.1 - 0.3 10.9 5.0 0.66 9.8 5.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 OAG04900.1 - 0.61 10.0 15.1 5.9 6.8 15.1 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG04900.1 - 1.3 9.3 8.5 0.075 13.2 3.4 1.6 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 OAG04901.1 - 1.2e-59 201.9 0.0 9.1e-59 199.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04901.1 - 8.2e-29 100.7 0.3 3.8e-20 72.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG04901.1 - 0.00057 19.3 0.5 0.0029 17.0 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.24 OAG04901.1 - 0.0006 20.5 0.2 0.003 18.2 0.2 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 OAG04901.1 - 0.0019 18.2 0.6 0.046 13.6 0.5 2.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG04901.1 - 0.0079 15.2 0.0 0.022 13.7 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG04901.1 - 0.026 13.9 0.0 0.078 12.3 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 OAG04902.1 - 7.6e-50 169.0 0.0 6.9e-27 94.6 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG04902.1 - 4.6e-16 59.5 1.7 0.00012 22.0 0.0 4.4 3 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG04902.1 - 1.5e-12 47.4 0.7 0.0019 17.7 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 OAG04902.1 - 2e-08 34.0 0.0 4.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 OAG04902.1 - 1.3e-07 32.3 0.5 0.015 15.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 OAG04902.1 - 2e-07 31.1 0.0 0.0032 17.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OAG04902.1 - 5.9e-07 29.1 0.5 0.0089 15.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG04902.1 - 2.9e-06 27.3 0.1 0.022 14.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 OAG04902.1 - 3.2e-05 24.3 0.0 0.022 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG04902.1 - 5.3e-05 23.5 0.0 0.34 11.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OAG04902.1 - 5.3e-05 23.2 0.1 0.059 13.3 0.0 3.1 3 0 0 3 3 3 1 NACHT domain DUF87 PF01935.17 OAG04902.1 - 0.00017 21.8 0.4 0.087 12.9 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_15 PF13175.6 OAG04902.1 - 0.0002 21.2 0.1 0.29 10.8 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 OAG04902.1 - 0.0004 20.9 0.1 0.68 10.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain HEAT PF02985.22 OAG04902.1 - 0.0015 18.6 0.3 26 5.4 0.0 5.6 6 0 0 6 6 5 0 HEAT repeat MeaB PF03308.16 OAG04902.1 - 0.0023 16.9 0.4 0.49 9.3 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 OAG04902.1 - 0.0027 17.9 0.1 1.3 9.3 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SR-25 PF10500.9 OAG04902.1 - 0.0035 17.0 2.1 0.0066 16.1 2.1 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RNA_helicase PF00910.22 OAG04902.1 - 0.0035 17.7 0.0 3 8.3 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 OAG04902.1 - 0.0036 17.5 0.0 5.8 7.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 OAG04902.1 - 0.0038 16.0 0.0 1.3 7.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG04902.1 - 0.0046 17.4 0.0 5.3 7.5 0.0 3.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG04902.1 - 0.0058 17.0 0.0 3.9 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain DUF3584 PF12128.8 OAG04902.1 - 0.014 13.0 1.7 0.7 7.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF815 PF05673.13 OAG04902.1 - 0.015 14.4 0.7 0.51 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 OAG04902.1 - 0.017 14.9 0.0 0.83 9.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OAG04902.1 - 0.018 14.7 0.2 1.9 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG04902.1 - 0.021 14.5 0.3 8.9 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 OAG04902.1 - 0.023 14.7 0.0 9.2 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 OAG04902.1 - 0.025 14.6 0.0 0.47 10.5 0.0 2.6 2 1 0 2 2 2 0 Dynamin family Roc PF08477.13 OAG04902.1 - 0.027 14.7 0.0 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 OAG04902.1 - 0.046 13.3 0.5 11 5.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain HEAT_EZ PF13513.6 OAG04902.1 - 0.047 14.2 1.7 84 3.8 0.0 5.0 5 0 0 5 5 4 0 HEAT-like repeat NB-ARC PF00931.22 OAG04902.1 - 0.051 12.7 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 OAG04902.1 - 0.061 12.6 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 OAG04902.1 - 0.073 12.6 0.0 45 3.5 0.0 3.9 4 0 0 4 4 4 0 AAA domain Ploopntkinase3 PF18751.1 OAG04902.1 - 0.075 12.9 0.1 20 5.0 0.0 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 OAG04902.1 - 0.16 11.3 1.6 3 7.1 0.1 2.6 3 0 0 3 3 3 0 Zeta toxin LRR_6 PF13516.6 OAG04903.1 - 4e-07 29.6 0.0 13 6.2 0.0 6.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 OAG04903.1 - 4.7e-06 26.9 3.3 5 7.7 0.0 6.3 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAG04903.1 - 0.00017 21.7 7.3 11 7.0 0.0 6.8 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 OAG04903.1 - 0.024 14.4 0.4 16 5.4 0.0 4.7 6 1 0 6 6 6 0 Leucine rich repeat DdrB PF12747.7 OAG04903.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 DdrB-like protein S10_plectin PF03501.15 OAG04904.1 - 4.9e-41 138.7 0.1 5.9e-41 138.5 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 OAG04905.1 - 2.1e-60 203.3 0.2 2.1e-60 203.3 0.2 1.5 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain RdRP_5 PF07925.11 OAG04905.1 - 0.07 10.5 0.2 0.088 10.2 0.2 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 DFF40 PF09230.10 OAG04905.1 - 1 8.9 5.5 1.5 8.4 5.5 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa DUF5302 PF17227.2 OAG04905.1 - 6.8 7.8 7.9 1.2 10.2 2.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5302) DNA_pol3_delta2 PF13177.6 OAG04907.1 - 1.7e-10 40.9 0.0 3.8e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 OAG04907.1 - 3.5e-06 27.5 0.2 9.2e-06 26.1 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG04907.1 - 1.2e-05 25.5 0.5 0.00054 20.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG04907.1 - 0.00076 19.9 1.0 0.0078 16.6 0.4 2.6 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 OAG04907.1 - 0.002 18.1 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 OAG04907.1 - 0.0021 17.8 0.8 0.0053 16.5 0.3 1.9 2 1 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 OAG04907.1 - 0.0022 18.4 0.1 0.0066 16.8 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain ABC_tran PF00005.27 OAG04907.1 - 0.033 14.7 0.1 0.063 13.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 OAG04907.1 - 0.062 12.1 0.1 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ADH_N PF08240.12 OAG04908.1 - 2.8e-25 88.3 1.2 4.7e-25 87.6 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG04908.1 - 9.6e-23 80.6 0.5 1.5e-22 80.0 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG04908.1 - 2.9e-06 28.4 0.4 5.9e-06 27.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG04908.1 - 0.009 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Pkinase PF00069.25 OAG04909.1 - 1e-66 225.0 0.0 2.4e-66 223.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04909.1 - 1.2e-45 155.8 0.0 2.1e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 OAG04909.1 - 4.7e-27 94.3 0.0 9.7e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 OAG04909.1 - 1.4e-17 63.9 0.2 2.8e-17 62.9 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAG04909.1 - 3.4e-17 62.3 0.2 9.4e-17 60.9 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 OAG04909.1 - 3.5e-08 33.1 0.1 2.5e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 OAG04909.1 - 0.00052 20.6 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 OAG04909.1 - 0.0028 17.6 0.1 0.0063 16.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 OAG04909.1 - 0.0092 16.1 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 IGR protein motif SAM_PNT PF02198.16 OAG04909.1 - 0.025 14.5 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Pkinase_fungal PF17667.1 OAG04909.1 - 0.041 12.7 0.5 0.15 10.8 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OAG04909.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 OAG04909.1 - 0.13 11.2 1.1 3.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Haspin like kinase domain MAP70 PF07058.11 OAG04909.1 - 0.9 8.2 4.4 2 7.1 4.4 1.6 1 1 0 1 1 1 0 Microtubule-associated protein 70 Peptidase_M20 PF01546.28 OAG04911.1 - 1.2e-31 110.0 0.0 3.4e-31 108.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG04911.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Fer2_4 PF13510.6 OAG04911.1 - 0.11 12.5 0.4 9 6.4 0.0 2.9 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Peptidase_M28 PF04389.17 OAG04911.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 AdoMet_MTase PF07757.13 OAG04912.1 - 8.6e-35 119.5 0.2 1.7e-17 63.8 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 OAG04912.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3240 PF11582.8 OAG04912.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) MFS_1 PF07690.16 OAG04913.1 - 8.8e-31 107.1 49.7 7.4e-18 64.6 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 OAG04914.1 - 8.7e-11 42.1 0.0 1.2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG04914.1 - 5e-07 30.1 0.1 7.2e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG04914.1 - 5.7e-07 29.5 0.1 7.7e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cass2 PF14526.6 OAG04914.1 - 0.046 13.9 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Integron-associated effector binding protein DUF1996 PF09362.10 OAG04915.1 - 3.9e-65 220.1 0.3 3.9e-65 220.1 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Glyco_hydro_45 PF02015.16 OAG04917.1 - 1.4e-55 188.5 11.8 1.7e-55 188.2 11.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Zn_clus PF00172.18 OAG04919.1 - 4.8e-07 29.8 8.6 1.1e-06 28.7 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG04919.1 - 0.00056 19.0 0.1 0.0024 17.0 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Epimerase PF01370.21 OAG04920.1 - 4.7e-12 45.9 0.0 1.9e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG04920.1 - 1.2e-06 28.2 0.1 1.8e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG04920.1 - 3.5e-06 27.1 0.0 5.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG04920.1 - 8.2e-05 21.7 0.1 0.00019 20.6 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG04920.1 - 0.00047 19.6 0.1 0.00086 18.8 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG04920.1 - 0.0012 18.1 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG04920.1 - 0.0013 17.9 0.1 0.014 14.5 0.1 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG04920.1 - 0.0037 16.5 0.0 0.0078 15.4 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein SKG6 PF08693.10 OAG04921.1 - 9.5e-09 34.5 0.3 9.5e-09 34.5 0.3 2.0 2 0 0 2 2 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 OAG04921.1 - 0.00045 20.7 9.4 0.00082 19.8 9.4 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM51 PF15345.6 OAG04921.1 - 0.00081 19.3 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 SR-25 PF10500.9 OAG04921.1 - 0.0058 16.3 14.5 0.0098 15.5 14.5 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BatD PF13584.6 OAG04921.1 - 0.0093 14.8 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance Alpha_GJ PF03229.13 OAG04921.1 - 0.037 14.6 7.2 0.073 13.6 7.2 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J TMEM154 PF15102.6 OAG04921.1 - 0.054 13.4 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF1180 PF06679.12 OAG04921.1 - 0.074 13.5 2.1 0.12 12.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mid2 PF04478.12 OAG04921.1 - 0.075 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Apt1 PF10351.9 OAG04921.1 - 0.15 10.9 1.8 0.17 10.7 1.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 OAG04921.1 - 0.18 8.9 1.3 0.21 8.7 1.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RIFIN PF02009.16 OAG04921.1 - 0.26 11.1 0.0 0.32 10.9 0.0 1.1 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 OAG04921.1 - 10 4.6 9.6 13 4.2 9.6 1.1 1 0 0 1 1 1 0 Macoilin family ZZ PF00569.17 OAG04922.1 - 0.14 12.0 1.3 3.6 7.5 0.7 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type RRM_1 PF00076.22 OAG04923.1 - 1.5e-08 34.3 0.1 3e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1687 PF07955.11 OAG04924.1 - 4.9e-28 98.2 0.0 6.9e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) RNaseH_like PF04308.12 OAG04924.1 - 0.032 14.1 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease H-like Ribosomal_S30 PF04758.14 OAG04925.1 - 1.2e-29 102.2 7.8 1.4e-29 102.1 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pyrid_oxidase_2 PF13883.6 OAG04926.1 - 2.7e-44 151.1 0.0 3.3e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Shal-type PF11601.8 OAG04926.1 - 0.08 12.5 0.2 17 5.1 0.1 2.7 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal zf-C2H2 PF00096.26 OAG04927.1 - 2.1e-09 37.3 10.3 0.00028 21.2 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG04927.1 - 2.6e-06 27.6 9.1 1.5e-05 25.2 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG04927.1 - 5.6e-05 23.6 9.4 0.094 13.6 1.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG04927.1 - 0.012 15.6 0.9 0.012 15.6 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 OAG04927.1 - 0.074 13.5 1.8 0.074 13.5 1.8 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 OAG04927.1 - 0.35 11.0 2.5 4.6 7.4 0.3 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 OAG04927.1 - 2.3 8.6 9.8 0.41 11.0 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.16 OAG04927.1 - 3.8 7.9 6.9 0.24 11.7 0.7 2.2 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_ribbon_SprT PF17283.2 OAG04927.1 - 8.8 6.3 11.5 0.29 11.1 1.4 2.8 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Mt_ATP-synt_D PF05873.12 OAG04932.1 - 1.9e-22 79.8 1.1 2.4e-22 79.4 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF148 PF02520.17 OAG04932.1 - 0.017 15.2 2.0 0.037 14.1 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF148 KASH_CCD PF14662.6 OAG04932.1 - 0.04 13.7 1.9 2.6 7.8 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH E3_UbLigase_R4 PF13764.6 OAG04932.1 - 0.071 11.3 0.4 0.085 11.0 0.4 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF2799 PF10973.8 OAG04932.1 - 0.08 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2799) DUF2408 PF10303.9 OAG04932.1 - 0.088 13.4 1.4 0.13 12.9 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Tropomyosin_1 PF12718.7 OAG04932.1 - 0.29 11.3 5.8 1.4 9.1 3.1 2.2 1 1 0 2 2 2 0 Tropomyosin like NPV_P10 PF05531.12 OAG04932.1 - 1.6 9.2 5.3 38 4.8 2.3 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein NAC PF01849.18 OAG04933.1 - 3.4e-24 84.6 0.1 1.4e-23 82.7 0.0 1.9 2 0 0 2 2 2 1 NAC domain RNA_pol_3_Rpc31 PF11705.8 OAG04933.1 - 0.0096 16.2 2.7 0.0096 16.2 2.7 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 SelP_N PF04592.14 OAG04933.1 - 0.78 9.1 5.9 1.3 8.4 5.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Myc_N PF01056.18 OAG04933.1 - 1.2 9.0 15.3 0.043 13.7 8.2 1.7 1 1 0 2 2 2 0 Myc amino-terminal region PGA2 PF07543.12 OAG04933.1 - 2.7 8.0 11.8 3.8 7.5 6.5 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF4407 PF14362.6 OAG04933.1 - 8.1 5.7 7.2 20 4.4 4.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_L14e PF01929.17 OAG04934.1 - 1e-30 106.0 1.4 1.4e-30 105.6 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OAG04934.1 - 0.0021 18.0 2.6 0.0041 17.0 2.6 1.6 1 0 0 1 1 1 1 KOW motif Prot_ATP_ID_OB PF16450.5 OAG04934.1 - 0.093 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Nup35_RRM PF05172.13 OAG04936.1 - 0.0021 18.0 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Arf PF00025.21 OAG04937.1 - 5.4e-50 169.3 0.0 5.9e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAG04937.1 - 3.9e-09 36.2 0.0 6.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 OAG04937.1 - 0.00047 20.3 0.0 0.00062 20.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG04937.1 - 0.002 17.7 0.0 0.0025 17.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG04937.1 - 0.024 14.0 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG04937.1 - 0.033 14.3 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 OAG04937.1 - 0.064 12.7 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Imm27 PF15590.6 OAG04940.1 - 0.15 11.8 0.2 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 27 HRXXH PF13933.6 OAG04941.1 - 7.1e-05 22.5 0.6 0.00023 20.8 0.0 1.9 2 0 0 2 2 2 1 Putative peptidase family Aspzincin_M35 PF14521.6 OAG04941.1 - 7.5e-05 23.3 0.7 0.038 14.5 0.2 2.2 2 0 0 2 2 2 2 Lysine-specific metallo-endopeptidase EptA_B_N PF08019.12 OAG04942.1 - 0.011 15.6 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB F-box-like PF12937.7 OAG04943.1 - 1.3e-07 31.4 0.2 4e-07 29.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG04943.1 - 0.0026 17.6 5.6 0.77 9.7 0.1 3.2 3 0 0 3 3 3 2 F-box domain MFS_1 PF07690.16 OAG04944.1 - 2.2e-38 132.1 3.3 2.2e-38 132.1 3.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04944.1 - 1.1e-11 44.4 1.4 1.1e-11 44.4 1.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG04944.1 - 0.0011 17.6 0.9 0.0021 16.6 0.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 OAG04944.1 - 0.0049 15.8 5.8 0.0049 15.8 5.8 3.1 2 2 0 2 2 2 1 MFS_1 like family Folate_carrier PF01770.18 OAG04944.1 - 0.013 14.3 0.0 0.031 13.0 0.0 1.5 1 1 0 1 1 1 0 Reduced folate carrier CRA PF06589.11 OAG04944.1 - 0.29 11.2 0.4 0.93 9.6 0.4 1.8 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) S-antigen PF05756.11 OAG04944.1 - 0.56 10.6 4.2 3.3 8.2 0.1 2.4 2 0 0 2 2 2 0 S-antigen protein DUF3487 PF11990.8 OAG04944.1 - 2.4 8.1 4.3 0.85 9.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF4611 PF15387.6 OAG04944.1 - 5.7 7.2 11.9 0.76 10.0 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LtrA PF06772.11 OAG04945.1 - 6.2e-23 81.6 19.5 6.2e-23 81.6 19.5 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF2330 PF10092.9 OAG04946.1 - 0.041 13.0 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Zn_ribbon_17 PF17120.5 OAG04948.1 - 3.2e-16 58.7 11.0 5.5e-16 57.9 11.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 OAG04948.1 - 2.2e-09 37.8 6.4 0.0028 18.4 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat C1_2 PF03107.16 OAG04948.1 - 0.0066 16.7 1.8 0.014 15.7 1.8 1.5 1 0 0 1 1 1 1 C1 domain zf-RING_2 PF13639.6 OAG04948.1 - 0.89 9.9 10.2 2 8.8 10.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OAG04948.1 - 1.2 9.2 7.1 2.2 8.3 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Sigma70_ner PF04546.13 OAG04948.1 - 1.3 8.8 6.1 0.24 11.3 1.3 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-RING_11 PF17123.5 OAG04948.1 - 1.6 8.6 5.6 3.5 7.5 5.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger UQ_con PF00179.26 OAG04949.1 - 3.9e-49 165.9 0.0 4.4e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG04949.1 - 0.00065 19.4 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAG04949.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OAG04949.1 - 0.089 13.1 0.2 0.17 12.1 0.2 1.8 1 1 0 1 1 1 0 RWD domain Herpes_pp38 PF04846.13 OAG04950.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein DUF5599 PF18141.1 OAG04951.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) Pkinase PF00069.25 OAG04953.1 - 5.8e-23 81.6 0.0 6.9e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04953.1 - 1.3e-13 50.9 0.0 1.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAG04953.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 OAG04953.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Lyase_1 PF00206.20 OAG04954.1 - 1.2e-92 310.7 0.0 1.8e-92 310.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OAG04954.1 - 1.6e-22 80.0 0.0 4.4e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF5316 PF17247.2 OAG04955.1 - 0.017 15.1 1.3 0.017 15.1 1.3 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5316) Clostridium_P47 PF06597.11 OAG04955.1 - 1.1 7.9 4.3 1.2 7.8 4.3 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein TRP PF06011.12 OAG04957.1 - 1.2e-123 413.0 18.2 2.2e-123 412.1 18.2 1.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG04957.1 - 8.9e-37 126.5 0.0 1.3e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF2427 PF10348.9 OAG04957.1 - 1.9 8.3 9.8 0.077 12.8 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) GFA PF04828.14 OAG04959.1 - 1e-05 25.8 0.1 1e-05 25.8 0.1 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 OAG04959.1 - 0.00088 18.9 0.6 0.00088 18.9 0.6 2.4 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain Ribosomal_L37e PF01907.19 OAG04959.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.5 3 0 0 3 3 3 0 Ribosomal protein L37e zf-CCHC PF00098.23 OAG04960.1 - 0.025 14.7 0.3 0.045 13.8 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAG04960.1 - 0.058 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-ANAPC11 PF12861.7 OAG04961.1 - 0.086 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2 PF00096.26 OAG04963.1 - 6.4e-12 45.2 11.0 6e-06 26.4 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG04963.1 - 1.7e-08 34.6 12.6 0.00017 22.1 0.7 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG04963.1 - 2.2e-07 31.0 11.4 1.5e-05 25.2 2.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG04963.1 - 8.8e-05 22.7 3.4 0.0032 17.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OAG04963.1 - 0.0001 22.0 7.7 0.017 14.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 OAG04963.1 - 0.002 18.1 5.2 0.45 10.6 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 OAG04963.1 - 0.016 15.7 8.3 1 9.8 0.9 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 OAG04963.1 - 0.045 13.5 2.2 1.8 8.4 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 OAG04963.1 - 0.39 11.2 0.1 0.39 11.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-AN1 PF01428.16 OAG04963.1 - 7.1 6.9 8.5 20 5.5 2.0 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger Pkinase PF00069.25 OAG04965.1 - 1.1e-66 224.9 0.2 1.1e-65 221.6 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Fungal_KA1 PF16797.5 OAG04965.1 - 1.8e-35 121.2 0.0 5e-35 119.7 0.0 1.8 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 OAG04965.1 - 1.7e-29 102.9 0.0 3.3e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG04965.1 - 0.0024 16.9 0.1 0.0051 15.8 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG04965.1 - 0.0037 16.6 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAG04965.1 - 0.047 13.3 0.2 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 OAG04965.1 - 0.078 12.9 0.0 0.078 12.9 0.0 2.8 4 0 0 4 4 4 0 Phosphotransferase enzyme family Ribosomal_L24e PF01246.20 OAG04966.1 - 1.6e-28 98.7 0.2 1.6e-28 98.7 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e FMN_dh PF01070.18 OAG04968.1 - 7.8e-117 390.2 0.0 9.5e-117 389.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 OAG04968.1 - 2.2e-05 23.9 0.0 0.12 11.6 0.0 2.5 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 OAG04968.1 - 6.5e-05 22.1 0.1 0.00012 21.2 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG04968.1 - 0.00031 20.0 0.2 0.00046 19.4 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG04968.1 - 0.015 14.8 0.2 2.5 7.5 0.1 2.6 1 1 1 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 OAG04968.1 - 0.038 13.4 1.0 0.069 12.5 1.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase IGPS PF00218.21 OAG04968.1 - 0.12 11.5 0.2 0.34 10.0 0.1 1.8 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase p450 PF00067.22 OAG04969.1 - 7.9e-77 259.0 0.0 9.6e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SF3a60_bindingd PF12108.8 OAG04970.1 - 0.64 9.9 6.6 8.1 6.4 0.1 2.9 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain Diphthamide_syn PF01866.17 OAG04972.1 - 5.3e-111 370.9 0.0 6.5e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COG6 PF06419.11 OAG04974.1 - 0.059 11.6 0.4 0.085 11.1 0.4 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 ZapB PF06005.12 OAG04974.1 - 3.4 8.2 13.6 3.6 8.1 0.5 2.7 2 1 1 3 3 3 0 Cell division protein ZapB MDMPI_N PF11716.8 OAG04974.1 - 6.6 7.4 9.1 3.1 8.5 3.4 2.9 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain Macoilin PF09726.9 OAG04976.1 - 0.048 12.2 8.4 0.056 12.0 8.4 1.0 1 0 0 1 1 1 0 Macoilin family Trypan_PARP PF05887.11 OAG04976.1 - 0.13 12.2 14.0 0.28 11.1 14.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 OAG04976.1 - 1.4 7.1 13.1 1.8 6.8 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 OAG04976.1 - 2.4 7.9 12.0 3.5 7.4 12.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Coiled PF05710.12 OAG04976.1 - 2.9 8.8 10.8 0.82 10.5 6.7 2.0 2 0 0 2 2 2 0 Coiled coil RR_TM4-6 PF06459.12 OAG04976.1 - 4.2 7.1 18.1 5.9 6.6 18.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 OAG04976.1 - 5.4 6.9 22.7 6.7 6.6 22.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.22 OAG04976.1 - 5.5 6.1 4.7 5.8 6.0 4.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OAG04976.1 - 7.7 6.5 5.8 11 6.0 5.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2470 PF10615.9 OAG04977.1 - 3.2e-18 66.1 0.2 5.4e-18 65.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Aminotran_3 PF00202.21 OAG04978.1 - 2.6e-113 378.7 0.0 3.5e-113 378.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG04978.1 - 1.6e-05 24.3 0.0 8.7e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II RNase_PH PF01138.21 OAG04980.1 - 1.5e-19 70.8 0.0 2.5e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 BTB PF00651.31 OAG04981.1 - 1.1e-23 83.5 0.2 2.6e-11 43.7 0.2 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 OAG04981.1 - 2.2e-08 34.2 0.1 5.6e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG04981.1 - 2e-07 31.2 0.1 0.0012 19.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAG04981.1 - 2.8e-07 31.0 0.1 6.6e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG04981.1 - 5.1e-07 30.1 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG04981.1 - 6e-06 26.2 0.7 0.02 15.4 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeat DUF3342 PF11822.8 OAG04981.1 - 0.038 14.2 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) UCH_C PF18031.1 OAG04981.1 - 0.044 13.7 0.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases Pkinase PF00069.25 OAG04982.1 - 2.3e-60 204.2 0.4 2e-36 125.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG04982.1 - 1.8e-34 119.2 0.0 4.6e-23 81.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG04982.1 - 0.0021 17.4 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG04982.1 - 0.019 14.9 0.1 0.067 13.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG04982.1 - 0.057 12.2 0.8 0.35 9.6 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase DUF4477 PF14780.6 OAG04982.1 - 0.57 9.8 5.1 0.29 10.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) DLH PF01738.18 OAG04984.1 - 3.4e-15 56.2 0.0 5.3e-15 55.6 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Pyr_redox_2 PF07992.14 OAG04985.1 - 2.3e-33 115.7 0.2 2.9e-33 115.4 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG04985.1 - 4e-10 40.1 1.4 2.3e-08 34.5 1.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG04985.1 - 5.9e-07 29.0 1.6 1.6e-06 27.6 1.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG04985.1 - 0.00059 18.8 0.1 0.0023 16.8 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 OAG04985.1 - 0.0011 18.4 0.5 0.0062 15.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OAG04985.1 - 0.0026 17.4 1.2 4.8 6.7 0.0 3.5 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG04985.1 - 0.025 14.6 3.6 5.6 6.9 0.0 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding Myosin_N PF02736.19 OAG04985.1 - 0.03 14.1 1.2 4.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain K_oxygenase PF13434.6 OAG04985.1 - 0.1 11.7 0.4 0.32 10.1 0.1 1.8 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAG04985.1 - 0.13 11.5 0.4 0.7 9.1 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG04985.1 - 0.33 9.9 4.9 0.25 10.4 0.1 2.7 4 0 0 4 4 4 0 Lycopene cyclase protein NAC PF01849.18 OAG04986.1 - 4.3e-23 81.0 0.1 8.8e-23 80.0 0.1 1.6 1 0 0 1 1 1 1 NAC domain SR-25 PF10500.9 OAG04986.1 - 0.0011 18.7 0.8 0.0019 17.9 0.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Hamartin PF04388.12 OAG04986.1 - 0.13 11.0 0.7 0.17 10.5 0.7 1.2 1 0 0 1 1 1 0 Hamartin protein Ctr PF04145.15 OAG04987.1 - 7e-32 111.1 1.3 8.4e-32 110.8 1.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF456 PF04306.13 OAG04987.1 - 0.011 16.1 5.4 0.02 15.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Peptidase_C41 PF05417.11 OAG04987.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Hepatitis E cysteine protease Ferric_reduct PF01794.19 OAG04988.1 - 9.2e-22 77.5 10.4 2.4e-21 76.1 10.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG04988.1 - 1e-18 67.4 0.1 9.2e-18 64.3 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG04988.1 - 9.8e-18 64.7 0.0 9.5e-17 61.5 0.0 2.4 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 OAG04988.1 - 0.0012 19.1 0.0 0.3 11.5 0.0 3.1 3 1 0 3 3 3 1 Oxidoreductase FAD-binding domain DUF983 PF06170.12 OAG04988.1 - 8.3 6.9 11.5 0.84 10.1 5.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Staufen_C PF16482.5 OAG04989.1 - 0.047 13.9 0.0 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 Staufen C-terminal domain adh_short PF00106.25 OAG04990.1 - 1.5e-30 106.2 0.0 3.8e-30 104.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG04990.1 - 2.6e-19 69.7 0.0 4.4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG04990.1 - 9.4e-06 25.6 0.1 6.4e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 OAG04991.1 - 1.3e-13 51.1 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG04991.1 - 1.3e-10 41.5 0.0 2.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding MFS_1 PF07690.16 OAG04992.1 - 2.2e-25 89.4 24.0 2.2e-25 89.4 24.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG04992.1 - 1e-11 44.4 8.8 1e-11 44.4 8.8 2.4 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG04992.1 - 6.2e-07 28.2 5.3 6.2e-07 28.2 5.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HbrB PF08539.11 OAG04993.1 - 1.6e-49 168.1 0.0 5.9e-49 166.3 0.0 2.0 2 0 0 2 2 2 1 HbrB-like Methyltransf_25 PF13649.6 OAG04993.1 - 3.4e-24 85.4 0.0 2.8e-23 82.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG04993.1 - 1.2e-23 83.5 0.0 4.5e-23 81.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG04993.1 - 1.6e-23 83.2 0.0 2.7e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG04993.1 - 6.2e-19 68.6 0.0 1.2e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG04993.1 - 1.5e-14 53.9 0.0 2.6e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG04993.1 - 8.6e-13 48.4 0.0 2.3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG04993.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG04993.1 - 1.4e-05 24.6 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 OAG04993.1 - 3.5e-05 23.5 0.0 8.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 OAG04993.1 - 9.4e-05 22.3 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 OAG04993.1 - 0.00011 21.6 0.1 0.00035 19.9 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_32 PF13679.6 OAG04993.1 - 0.0003 20.8 0.0 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG04993.1 - 0.00054 19.0 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 OAG04993.1 - 0.089 12.7 0.0 0.26 11.2 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.15 OAG04993.1 - 0.097 12.5 0.0 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase FtsJ PF01728.19 OAG04993.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 OAG04993.1 - 0.25 10.7 0.0 0.42 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_16 PF00722.21 OAG04995.1 - 2.2e-40 138.0 0.7 2.2e-40 138.0 0.7 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF2015 PF09435.10 OAG04995.1 - 0.094 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) DUF3828 PF12883.7 OAG04995.1 - 0.13 12.7 0.2 0.26 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) zf-CCCH_4 PF18044.1 OAG04996.1 - 4.3 7.2 8.1 24 4.9 5.3 2.7 2 1 0 2 2 2 0 CCCH-type zinc finger Ctf8 PF09696.10 OAG04997.1 - 3.5e-38 131.1 0.1 1.9e-36 125.5 0.1 2.0 1 1 0 1 1 1 1 Ctf8 HeLo PF14479.6 OAG05000.1 - 3.4e-14 53.2 0.3 3.6e-14 53.1 0.3 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF3611 PF12263.8 OAG05000.1 - 0.025 14.5 0.0 0.026 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) TPR_10 PF13374.6 OAG05001.1 - 1e-18 66.5 0.0 1.6e-12 46.8 0.0 3.9 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG05001.1 - 5.9e-17 61.7 0.0 6.5e-09 36.0 0.0 3.9 1 1 2 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.22 OAG05001.1 - 4.8e-10 39.0 0.0 8.5e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 OAG05001.1 - 0.0021 18.1 0.0 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG05001.1 - 0.0054 16.5 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG05001.1 - 0.012 15.7 1.4 0.039 14.1 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 OAG05001.1 - 0.015 15.7 2.7 0.095 13.1 2.7 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OAG05001.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG05001.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lipoprotein_2 PF00921.17 OAG05002.1 - 1.6 8.2 10.0 0.13 11.8 5.2 1.5 2 0 0 2 2 2 0 Borrelia lipoprotein Rgp1 PF08737.10 OAG05003.1 - 1.6e-157 525.0 0.0 4.6e-157 523.5 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 OAG05003.1 - 0.009 16.1 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DmpG_comm PF07836.11 OAG05003.1 - 0.18 11.4 0.4 0.86 9.2 0.4 2.1 1 1 0 1 1 1 0 DmpG-like communication domain FAD_binding_4 PF01565.23 OAG05005.1 - 4.3e-20 71.9 0.8 7.2e-20 71.1 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG05005.1 - 3.5e-08 33.4 0.0 9.6e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like HMGL-like PF00682.19 OAG05007.1 - 1.3e-45 156.1 0.0 7.2e-34 117.5 0.2 2.0 2 0 0 2 2 2 2 HMGL-like SecE PF00584.20 OAG05008.1 - 0.59 10.1 10.5 2.3 8.2 0.4 2.5 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Tmemb_14 PF03647.13 OAG05009.1 - 3.5e-24 85.3 3.8 4e-24 85.2 3.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PGF-CTERM PF18204.1 OAG05009.1 - 0.047 13.7 3.3 3.9 7.6 0.0 3.2 2 1 0 2 2 2 0 PGF-CTERM motif Gram_pos_anchor PF00746.21 OAG05009.1 - 0.68 9.9 6.8 0.78 9.7 0.1 3.4 4 0 0 4 4 4 0 LPXTG cell wall anchor motif SKN1 PF03935.15 OAG05010.1 - 1.6e-231 769.1 0.9 1.9e-231 768.8 0.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) NuiA PF07924.11 OAG05011.1 - 1e-05 25.9 3.9 0.012 16.0 0.1 2.5 1 1 1 2 2 2 2 Nuclease A inhibitor-like protein DUF4663 PF15668.5 OAG05011.1 - 0.033 13.3 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) TPR_1 PF00515.28 OAG05012.1 - 2e-58 192.0 25.1 1.1e-08 34.5 0.0 10.8 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAG05012.1 - 3.9e-50 163.9 19.2 1.5e-06 27.9 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAG05012.1 - 3.3e-41 136.0 18.0 2.1e-07 30.6 0.0 10.7 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 OAG05012.1 - 3e-31 105.5 14.9 2e-05 24.6 0.1 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAG05012.1 - 5.9e-28 96.3 22.0 1e-06 28.3 1.0 9.6 5 2 4 9 9 9 6 TPR repeat TPR_16 PF13432.6 OAG05012.1 - 1.5e-27 95.9 6.9 2.9e-07 31.0 0.1 6.8 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAG05012.1 - 7.3e-26 88.6 9.6 8e-06 26.3 0.1 8.6 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 OAG05012.1 - 8.3e-26 90.3 11.3 0.00025 21.5 0.1 7.1 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAG05012.1 - 2.5e-24 85.3 17.2 2.6e-05 24.4 0.6 7.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG05012.1 - 6.1e-22 76.0 13.7 0.0097 15.9 0.1 9.5 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 OAG05012.1 - 3.7e-20 71.1 19.5 0.0023 18.5 0.0 9.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAG05012.1 - 1.1e-15 57.5 11.2 0.0006 19.9 0.1 6.9 2 1 7 9 9 9 7 Tetratricopeptide repeat TPR_15 PF13429.6 OAG05012.1 - 3.6e-11 42.8 9.0 0.0087 15.3 0.2 5.2 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_21 PF09976.9 OAG05012.1 - 2.5e-09 37.1 1.8 0.043 13.5 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 OAG05012.1 - 1.1e-08 35.1 14.0 4e-08 33.4 2.9 3.7 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OAG05012.1 - 8e-05 23.1 6.1 1 9.8 0.0 3.5 3 0 0 3 3 3 2 Bacterial transcriptional activator domain Syntaxin-6_N PF09177.11 OAG05012.1 - 0.0013 19.2 0.3 1.3 9.7 0.0 2.7 2 0 0 2 2 2 1 Syntaxin 6, N-terminal TPR_10 PF13374.6 OAG05012.1 - 0.0029 17.4 21.3 2.4 8.2 0.0 7.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG05012.1 - 0.011 15.1 7.7 0.77 9.1 0.1 3.6 2 2 1 3 3 3 0 MalT-like TPR region DUF2225 PF09986.9 OAG05012.1 - 0.012 15.3 3.5 0.36 10.5 0.1 3.2 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 OAG05012.1 - 0.043 14.2 5.5 0.35 11.2 0.1 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.10 OAG05012.1 - 0.11 11.5 1.1 11 4.9 0.2 2.9 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 OAG05012.1 - 0.87 9.7 20.3 9.6 6.4 1.3 6.8 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 OAG05012.1 - 1 8.7 18.3 15 4.9 0.5 5.3 1 1 4 5 5 5 0 Soluble NSF attachment protein, SNAP Aldedh PF00171.22 OAG05014.1 - 4.8e-122 407.8 0.0 6e-122 407.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cyt_bd_oxida_II PF02322.15 OAG05014.1 - 0.038 13.3 0.2 0.067 12.5 0.2 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Fimbrial_PilY2 PF14481.6 OAG05014.1 - 0.19 11.4 0.1 2.7 7.7 0.0 2.6 3 0 0 3 3 3 0 Type 4 fimbrial biogenesis protein PilY2 Gln-synt_C PF00120.24 OAG05015.1 - 7.2e-84 281.7 0.0 9e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 OAG05016.1 - 1.9e-57 194.5 0.3 2.1e-57 194.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG05016.1 - 4.1e-39 134.1 0.0 5.3e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG05016.1 - 1.3e-07 31.7 0.7 2e-07 31.1 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG05016.1 - 0.0003 20.7 0.0 0.00064 19.6 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ChuX_HutX PF06228.13 OAG05016.1 - 0.0053 16.5 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 2 Haem utilisation ChuX/HutX Methyltransf_12 PF08242.12 OAG05016.1 - 0.0067 17.1 0.0 0.014 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 OAG05016.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2388 PF09498.10 OAG05016.1 - 0.02 14.8 0.3 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) RecC_C PF17946.1 OAG05016.1 - 0.043 13.6 0.1 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 RecC C-terminal domain zf-RING-like PF08746.11 OAG05017.1 - 3.3 8.1 5.7 7.3 7.0 5.7 1.7 1 0 0 1 1 1 0 RING-like domain Thioredoxin PF00085.20 OAG05018.1 - 9.4e-25 86.6 0.0 1.1e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG05018.1 - 1.1e-07 31.5 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAG05018.1 - 1.3e-06 28.7 0.0 2.8e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OAG05018.1 - 4.2e-05 24.0 0.3 0.00028 21.3 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAG05018.1 - 6.7e-05 22.8 0.0 9.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG05018.1 - 0.0007 19.3 0.1 0.0022 17.7 0.1 1.7 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 OAG05018.1 - 0.001 18.8 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 OAG05018.1 - 0.0031 17.4 0.1 0.0045 16.8 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OAG05018.1 - 0.036 14.3 0.2 0.06 13.5 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 OAG05018.1 - 0.036 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 OAG05018.1 - 0.05 13.3 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 OAG05018.1 - 0.089 12.9 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin domain Hexokinase_2 PF03727.16 OAG05019.1 - 3.6e-77 259.0 0.0 4.8e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG05019.1 - 4.9e-73 245.3 0.0 7.5e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF5610 PF18433.1 OAG05019.1 - 0.032 14.7 0.1 0.07 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) DUF1996 PF09362.10 OAG05020.1 - 2.8e-80 269.7 2.1 3.5e-80 269.4 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Asp PF00026.23 OAG05022.1 - 9.6e-05 21.9 0.1 0.00073 19.1 0.1 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease PhoR PF11808.8 OAG05022.1 - 0.027 14.9 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Syndecan PF01034.20 OAG05022.1 - 0.48 10.4 1.7 1.1 9.2 1.7 1.5 1 0 0 1 1 1 0 Syndecan domain MFS_1 PF07690.16 OAG05023.1 - 8.3e-24 84.2 40.9 8.9e-23 80.8 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG05023.1 - 3e-10 39.6 4.6 3e-10 39.6 4.6 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter ApbA PF02558.16 OAG05024.1 - 2e-25 89.2 0.0 3.1e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAG05024.1 - 1e-23 83.9 0.0 1.6e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DEAD PF00270.29 OAG05026.1 - 3.7e-38 131.0 0.2 7.1e-38 130.1 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG05026.1 - 3.5e-27 95.0 0.4 3.7e-24 85.2 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAG05026.1 - 2.2e-09 37.6 0.0 4.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG05026.1 - 2.3e-05 23.9 0.2 0.00012 21.5 0.1 2.1 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.16 OAG05027.1 - 1.4e-23 82.9 0.2 2.9e-23 81.9 0.2 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain HNH_5 PF14279.6 OAG05027.1 - 0.00084 19.1 3.1 0.04 13.8 0.1 2.3 1 1 1 2 2 2 2 HNH endonuclease FA PF08736.11 OAG05027.1 - 0.94 9.6 8.6 2.4 8.3 0.0 3.1 3 0 0 3 3 3 0 FERM adjacent (FA) Abhydrolase_2 PF02230.16 OAG05028.1 - 2e-08 34.3 0.1 1e-05 25.4 0.0 3.0 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Adeno_52K PF03052.15 OAG05030.1 - 0.085 12.3 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa Ank_2 PF12796.7 OAG05031.1 - 1.4e-15 57.6 1.5 4e-08 33.7 0.2 2.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG05031.1 - 8.3e-15 54.9 1.1 4.7e-05 23.9 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG05031.1 - 1.7e-14 53.5 2.9 0.0003 21.1 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OAG05031.1 - 2.4e-12 45.9 0.6 0.00022 21.4 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OAG05031.1 - 5.6e-07 29.7 1.0 0.026 14.8 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 OAG05031.1 - 0.28 11.1 2.2 26 4.8 0.1 3.0 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain NACHT PF05729.12 OAG05032.1 - 4e-07 30.1 0.0 8.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG05032.1 - 5.5e-05 23.5 0.0 0.0002 21.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG05032.1 - 0.0054 17.2 0.2 0.032 14.6 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAG05032.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SesA PF17107.5 OAG05032.1 - 0.017 15.3 0.3 0.067 13.4 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ATPase PF06745.13 OAG05032.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 KaiC Helo_like_N PF17111.5 OAG05032.1 - 0.027 13.8 1.4 0.21 10.9 1.4 2.4 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 OAG05032.1 - 0.11 12.6 3.3 8.9 6.4 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 OAG05032.1 - 0.3 11.6 5.8 1.2 9.7 0.9 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein ERCC4 PF02732.15 OAG05034.1 - 4e-18 66.1 0.0 1e-17 64.8 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain Ribosomal_L37ae PF01780.19 OAG05035.1 - 2.6e-41 139.6 11.1 2.9e-41 139.5 11.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 OAG05035.1 - 0.0027 17.8 1.2 0.0038 17.3 1.2 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 OAG05035.1 - 0.0033 17.8 0.5 1.2 9.7 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double domain Ima1_N PF09779.9 OAG05035.1 - 0.016 16.1 0.2 0.022 15.6 0.2 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain DUF1451 PF07295.11 OAG05035.1 - 0.028 14.5 0.7 0.037 14.1 0.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Elf1 PF05129.13 OAG05035.1 - 0.05 13.6 2.7 0.076 13.1 2.7 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 OAG05035.1 - 0.078 13.0 5.6 0.16 11.9 5.6 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 OAG05035.1 - 0.081 13.0 5.8 2.5 8.2 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger CarbpepA_inh PF02977.15 OAG05035.1 - 0.14 12.0 4.3 0.78 9.6 0.7 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor C1_2 PF03107.16 OAG05035.1 - 0.25 11.7 2.7 1.8 9.0 2.8 1.9 1 1 1 2 2 2 0 C1 domain YyzF PF14116.6 OAG05035.1 - 0.33 11.0 1.4 0.73 9.9 0.2 1.9 2 0 0 2 2 2 0 YyzF-like protein Acetyltransf_4 PF13420.7 OAG05036.1 - 3.1e-16 59.9 0.0 8.4e-08 32.5 0.0 2.0 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG05036.1 - 3.3e-10 40.2 0.1 1.6e-09 38.0 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG05036.1 - 6.9e-09 36.0 0.0 1.3e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG05036.1 - 4.3e-07 29.9 0.0 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAG05036.1 - 0.00013 22.6 0.0 0.00016 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG05036.1 - 0.034 14.1 0.0 0.34 10.9 0.0 2.4 3 0 0 3 3 3 0 FR47-like protein p450 PF00067.22 OAG05038.1 - 1.4e-75 254.8 0.0 1.9e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PMT_4TMC PF16192.5 OAG05039.1 - 0.024 14.2 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase Sec6 PF06046.13 OAG05040.1 - 3.5e-160 534.1 14.7 3.5e-160 534.1 14.7 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF3535 PF12054.8 OAG05040.1 - 0.0012 18.1 0.1 0.0025 17.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) CIMR PF00878.18 OAG05040.1 - 0.38 10.8 2.0 21 5.2 0.4 2.5 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat FadA PF09403.10 OAG05040.1 - 9.7 6.7 10.7 0.28 11.7 1.5 3.1 3 1 0 3 3 3 0 Adhesion protein FadA zf-CSL PF05207.13 OAG05041.1 - 1.7e-20 72.5 1.3 2e-20 72.3 1.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Frataxin_Cyay PF01491.16 OAG05042.1 - 1.4e-33 115.2 0.0 1.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.20 OAG05043.1 - 4.4e-42 143.4 0.1 1.3e-41 141.8 0.1 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain HET PF06985.11 OAG05045.1 - 8.3e-32 110.5 2.1 2.9e-31 108.8 2.1 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SKG6 PF08693.10 OAG05046.1 - 0.015 14.7 0.0 0.038 13.4 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HLH PF00010.26 OAG05048.1 - 4.8e-09 36.0 0.0 1.7e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Oxidoreduct_C PF16490.5 OAG05049.1 - 0.083 12.6 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Putative oxidoreductase C terminal domain Glyco_transf_43 PF03360.16 OAG05050.1 - 0.047 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 43 Glyco_hydro_32N PF00251.20 OAG05051.1 - 4.1e-26 92.3 0.0 6.1e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain SEN1_N PF12726.7 OAG05054.1 - 1.2e-190 635.4 17.4 1.6e-190 635.0 17.4 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 OAG05054.1 - 1.3e-72 244.8 1.3 1.3e-72 244.8 1.3 2.8 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 OAG05054.1 - 1.2e-59 201.3 0.0 2.4e-59 200.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG05054.1 - 2.6e-12 46.9 0.2 2.1e-07 30.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG05054.1 - 5.1e-09 36.6 0.0 2.1e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OAG05054.1 - 2e-06 27.5 8.4 0.0001 22.0 1.0 3.9 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 OAG05054.1 - 3.5e-06 27.1 1.0 1.3e-05 25.3 0.3 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OAG05054.1 - 9e-06 25.6 0.2 0.021 14.6 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 OAG05054.1 - 0.00045 20.0 0.8 0.016 15.0 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase T2SSE PF00437.20 OAG05054.1 - 0.024 13.7 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 OAG05054.1 - 0.13 12.8 12.8 0.24 11.9 1.7 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG05054.1 - 0.18 12.1 2.4 1 9.7 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.19 OAG05054.1 - 0.22 10.9 4.4 1.3 8.4 0.1 3.5 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain Selenoprotein_S PF06936.11 OAG05054.1 - 0.25 11.1 8.8 0.75 9.6 8.8 1.7 1 0 0 1 1 1 0 Selenoprotein S (SelS) GvpG PF05120.12 OAG05054.1 - 0.62 10.1 3.3 2.9 7.9 1.0 2.9 2 0 0 2 2 2 0 Gas vesicle protein G PhoLip_ATPase_C PF16212.5 OAG05055.1 - 1.3e-76 257.7 27.6 1.3e-76 257.7 27.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG05055.1 - 2.8e-20 71.7 0.4 7.7e-20 70.4 0.4 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAG05055.1 - 4.2e-11 42.8 0.0 2e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAG05055.1 - 6.7e-10 39.6 0.2 5.7e-05 23.5 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAG05055.1 - 9.1e-05 22.1 1.6 0.0019 17.8 0.0 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAG05055.1 - 0.022 14.5 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TrbC PF04956.13 OAG05055.1 - 7.3 6.9 8.9 1.3 9.3 2.8 2.5 2 0 0 2 2 2 0 TrbC/VIRB2 family Tetraspanin PF00335.20 OAG05058.1 - 0.0018 18.1 7.1 0.0037 17.0 7.1 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF4131 PF13567.6 OAG05058.1 - 0.93 9.1 5.3 3.4 7.3 4.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SRF-TF PF00319.18 OAG05059.1 - 3.7e-21 74.3 0.1 5.2e-21 73.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AA_permease_2 PF13520.6 OAG05060.1 - 5.1e-54 183.7 56.0 6.1e-54 183.5 56.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG05060.1 - 5e-24 84.7 44.9 6.5e-24 84.4 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_2 PF00891.18 OAG05061.1 - 3.3e-20 72.3 0.0 5.3e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_Tnp_ISL3 PF13542.6 OAG05061.1 - 0.019 14.4 0.0 0.05 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Methyltransf_12 PF08242.12 OAG05061.1 - 0.041 14.6 0.0 0.14 13.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05061.1 - 0.047 14.4 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain HTH_AsnC-type PF13404.6 OAG05061.1 - 0.06 13.2 0.7 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain NAT PF04768.13 OAG05062.1 - 7.9e-43 146.0 0.1 1.3e-42 145.3 0.1 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 OAG05062.1 - 5.2e-32 110.8 0.0 1.7e-31 109.2 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 OAG05062.1 - 1.2e-28 100.4 0.1 5.2e-28 98.3 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family Biliv-reduc_cat PF09166.10 OAG05062.1 - 0.0084 16.4 0.2 0.019 15.2 0.2 1.5 1 0 0 1 1 1 1 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.22 OAG05062.1 - 0.022 15.6 0.0 0.056 14.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 OAG05062.1 - 0.026 14.8 0.0 0.072 13.3 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain POTRA_3 PF17287.2 OAG05062.1 - 0.026 14.0 0.0 0.075 12.5 0.0 1.7 1 0 0 1 1 1 0 POTRA domain DapB_N PF01113.20 OAG05062.1 - 0.05 13.7 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.21 OAG05063.1 - 6.8e-33 112.3 0.6 7.7e-33 112.1 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin Glyco_hydro_76 PF03663.14 OAG05064.1 - 6.9e-142 473.3 28.1 8e-142 473.1 28.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG05064.1 - 0.00037 19.7 12.6 0.03 13.4 0.7 3.0 2 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 GATase_6 PF13522.6 OAG05065.1 - 1.2e-15 57.9 0.0 3.2e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAG05065.1 - 4.4e-13 49.2 0.0 8.3e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OAG05065.1 - 4.6e-06 26.2 0.0 9.6e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CorA PF01544.18 OAG05066.1 - 4.3e-11 42.7 0.6 6.7e-11 42.0 0.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 OAG05066.1 - 0.039 13.7 0.1 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 Transposase partial_CstF PF15861.5 OAG05066.1 - 0.85 9.4 3.4 0.45 10.3 0.4 2.0 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain DUF1115 PF06544.12 OAG05067.1 - 0.094 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) UBA PF00627.31 OAG05068.1 - 4e-06 26.6 0.1 1.9e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain PIP5K PF01504.18 OAG05072.1 - 3.2e-41 141.4 0.0 1.6e-39 135.8 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SnoaL PF07366.12 OAG05073.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAG05073.1 - 0.014 16.0 0.1 0.063 13.9 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like domain Cyclin PF08613.11 OAG05075.1 - 4.1e-06 27.3 0.0 4.1e-06 27.3 0.0 2.1 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 OAG05075.1 - 0.011 15.5 0.3 0.021 14.5 0.3 1.5 1 1 0 1 1 1 0 Cyclin, N-terminal domain SRP-alpha_N PF04086.13 OAG05076.1 - 9e-74 249.0 0.0 1.2e-73 248.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 OAG05076.1 - 9.6e-49 165.7 0.1 1.6e-48 165.0 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OAG05076.1 - 1e-09 38.5 0.1 2.6e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OAG05076.1 - 1.1e-06 27.9 0.1 2.1e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 OAG05076.1 - 0.0028 18.1 0.2 0.015 15.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG05076.1 - 0.0032 17.9 0.1 0.0086 16.5 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 OAG05076.1 - 0.0036 17.0 0.2 0.0068 16.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG05076.1 - 0.049 14.2 0.0 0.093 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 OAG05076.1 - 0.094 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG05076.1 - 0.15 12.2 0.3 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG05076.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain YIF1 PF03878.15 OAG05077.1 - 5.2e-99 330.6 3.8 6e-99 330.4 3.8 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 OAG05077.1 - 7.6e-05 22.5 8.7 0.00017 21.4 8.7 1.5 1 0 0 1 1 1 1 Yip1 domain Glyco_hydro_16 PF00722.21 OAG05078.1 - 2.3e-11 43.5 2.8 3.2e-11 43.0 2.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 KRAB PF01352.27 OAG05078.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 KRAB box Mpv17_PMP22 PF04117.12 OAG05079.1 - 2.6e-14 53.2 2.7 3.4e-14 52.8 1.0 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family FAD_binding_2 PF00890.24 OAG05080.1 - 6.7e-58 196.7 0.6 8e-58 196.5 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG05080.1 - 2.2e-08 34.1 0.1 2.5e-07 30.6 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG05080.1 - 7e-06 26.2 0.0 2.1e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG05080.1 - 6.5e-05 22.3 1.8 0.00034 20.0 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG05080.1 - 7.3e-05 22.1 2.6 0.0038 16.5 0.4 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 OAG05080.1 - 0.0016 17.7 0.9 0.0076 15.5 0.9 1.9 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OAG05080.1 - 0.016 14.3 1.0 0.048 12.7 0.1 2.3 3 1 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAG05080.1 - 0.077 11.7 5.5 0.16 10.6 0.9 2.6 2 1 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 OAG05080.1 - 0.095 12.0 0.6 0.29 10.4 0.6 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Rad21_Rec8_N PF04825.13 OAG05081.1 - 2.1e-23 82.6 0.0 4e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAG05081.1 - 0.018 14.3 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein UCH PF00443.29 OAG05082.1 - 1.3e-52 178.9 0.0 1.6e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OAG05082.1 - 2.7e-13 49.4 0.1 8.1e-13 47.9 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 OAG05082.1 - 5e-11 42.8 10.2 9.1e-10 38.6 10.2 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ARPC4 PF05856.12 OAG05083.1 - 2.2e-79 264.9 3.9 2.4e-79 264.7 3.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) MmgE_PrpD PF03972.14 OAG05084.1 - 1.5e-145 485.2 0.0 2.3e-145 484.5 0.0 1.3 1 0 0 1 1 1 1 MmgE/PrpD family PIR PF00399.19 OAG05085.1 - 1.1e-36 123.6 73.5 3.9e-07 29.4 5.8 7.8 7 0 0 7 7 7 7 Yeast PIR protein repeat Coiled PF05710.12 OAG05086.1 - 0.12 13.3 7.5 0.057 14.2 5.8 1.4 2 0 0 2 2 2 0 Coiled coil VPS13_C PF16909.5 OAG05086.1 - 2.1 8.1 3.6 1.9 8.2 2.5 1.5 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Ala_racemase_N PF01168.20 OAG05087.1 - 4.8e-27 95.0 0.0 5.9e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 OAG05087.1 - 1.6e-19 70.3 0.0 6.3e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain GTP_CH_N PF12471.8 OAG05087.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Glyco_transf_4 PF13439.6 OAG05087.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 RGS PF00615.19 OAG05091.1 - 2.5e-05 24.5 0.0 0.00064 20.0 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pox_A14 PF05767.12 OAG05091.1 - 0.15 12.2 0.0 0.64 10.2 0.0 2.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Cyclase PF04199.13 OAG05092.1 - 3.7e-05 24.0 0.0 4.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF406 PF04175.12 OAG05098.1 - 4.1 7.9 7.6 8.8 6.9 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF406) SAP PF02037.27 OAG05099.1 - 1.5e-05 24.6 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain FAM199X PF15814.5 OAG05099.1 - 0.12 11.4 9.1 0.25 10.3 9.1 1.6 1 0 0 1 1 1 0 Protein family FAM199X RAP1 PF07218.11 OAG05099.1 - 8.8 4.5 9.2 13 4.0 9.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3435 PF11917.8 OAG05100.1 - 0.00037 19.6 0.7 0.0067 15.4 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF3435) zf-BED PF02892.15 OAG05100.1 - 0.2 11.7 0.8 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 BED zinc finger zf-C6H2 PF15801.5 OAG05100.1 - 0.94 9.8 4.6 19 5.7 1.2 2.4 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Cwf_Cwc_15 PF04889.12 OAG05100.1 - 1.1 8.9 12.6 0.41 10.3 3.1 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein IGR PF09597.10 OAG05101.1 - 0.13 12.4 0.0 7.4 6.8 0.0 2.3 2 0 0 2 2 2 0 IGR protein motif DLH PF01738.18 OAG05103.1 - 1.9e-17 63.6 1.4 9.7e-17 61.2 1.4 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family V-SNARE PF05008.15 OAG05104.1 - 3.9e-20 72.0 5.2 3.9e-20 72.0 5.2 2.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OAG05104.1 - 3.1e-16 59.4 4.2 3.1e-16 59.4 4.2 2.6 4 0 0 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAG05104.1 - 0.0053 16.7 1.5 0.0076 16.1 0.2 2.0 2 2 1 3 3 3 1 Sec20 Prominin PF05478.11 OAG05104.1 - 0.019 13.0 2.0 0.68 7.8 0.2 2.0 2 0 0 2 2 2 0 Prominin DUF1542 PF07564.11 OAG05104.1 - 0.025 14.7 1.9 0.08 13.1 1.9 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Spectrin PF00435.21 OAG05104.1 - 0.027 15.0 4.3 0.038 14.5 1.0 2.5 1 1 0 2 2 2 0 Spectrin repeat Cep57_CLD PF14073.6 OAG05104.1 - 0.052 13.6 7.8 0.075 13.0 7.8 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF2564 PF10819.8 OAG05104.1 - 0.35 11.3 3.9 0.17 12.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) PI3K_P85_iSH2 PF16454.5 OAG05104.1 - 0.38 10.3 6.9 0.071 12.7 1.8 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fusion_gly PF00523.18 OAG05104.1 - 0.55 8.4 3.7 0.22 9.7 0.5 1.8 2 0 0 2 2 2 0 Fusion glycoprotein F0 zf-C4H2 PF10146.9 OAG05104.1 - 0.84 9.9 6.3 2.1 8.6 6.4 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein Exonuc_VII_L PF02601.15 OAG05104.1 - 1.8 8.1 11.2 6.7 6.2 11.2 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 OAG05104.1 - 4.8 7.8 7.9 0.88 10.2 0.9 2.8 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) NAD_binding_8 PF13450.6 OAG05105.1 - 4.2e-12 46.1 0.0 9.2e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG05105.1 - 2e-10 40.6 0.2 1.2e-08 34.7 0.0 2.8 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 OAG05105.1 - 1.5e-07 31.3 0.2 0.00016 21.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG05105.1 - 0.003 17.6 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG05105.1 - 0.012 14.8 0.0 0.062 12.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG05105.1 - 0.023 15.2 0.0 0.076 13.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG05105.1 - 0.025 13.7 0.0 0.17 10.9 0.0 2.0 1 1 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 OAG05105.1 - 0.047 12.1 0.0 0.092 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Prenylcys_lyase PF07156.14 OAG05105.1 - 0.13 11.4 0.0 0.39 9.8 0.0 1.7 1 1 0 1 1 1 0 Prenylcysteine lyase eIF-1a PF01176.19 OAG05106.1 - 1.6e-17 63.1 0.0 2.1e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Glyco_hydro_63 PF03200.16 OAG05106.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain Methyltransf_23 PF13489.6 OAG05108.1 - 1.7e-14 54.0 0.0 2.5e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG05108.1 - 6.3e-13 49.3 0.0 1.3e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG05108.1 - 2.7e-12 47.2 0.0 5.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05108.1 - 8.3e-12 45.7 0.0 1.7e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG05108.1 - 2.4e-07 30.7 0.0 3.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG05108.1 - 5.5e-05 22.6 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family SelP_N PF04592.14 OAG05108.1 - 0.14 11.5 12.6 0.23 10.9 12.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TYW3 PF02676.14 OAG05109.1 - 3.4e-72 242.3 0.0 4.2e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.10 OAG05110.1 - 1.9e-78 263.2 0.0 2.5e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Zn_clus PF00172.18 OAG05113.1 - 6.5e-08 32.6 6.4 9.5e-08 32.0 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Corona_S2 PF01601.16 OAG05114.1 - 2.2 6.7 15.2 3 6.2 15.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein EutQ PF06249.12 OAG05115.1 - 1.1e-12 48.0 0.0 1.3e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 OAG05115.1 - 1.5e-08 34.2 0.0 1.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OAG05115.1 - 0.00027 20.6 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 OAG05115.1 - 0.0069 16.1 0.0 0.0079 15.9 0.0 1.1 1 0 0 1 1 1 1 Cupin Pirin PF02678.16 OAG05115.1 - 0.028 14.4 0.0 0.039 13.9 0.0 1.3 1 1 0 1 1 1 0 Pirin ARD PF03079.14 OAG05115.1 - 0.14 12.3 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.19 OAG05115.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain HET PF06985.11 OAG05116.1 - 2.5e-24 86.3 0.6 3.9e-24 85.7 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) vATP-synt_E PF01991.18 OAG05117.1 - 1.2e-67 227.2 10.8 1.5e-67 226.9 10.8 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Mg_trans_NIPA PF05653.14 OAG05118.1 - 7.9e-19 67.9 8.0 1.1e-18 67.4 8.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF3413 PF11893.8 OAG05118.1 - 0.0083 15.3 1.1 0.0083 15.3 1.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3413) PUNUT PF16913.5 OAG05118.1 - 0.1 11.8 10.9 0.38 9.9 10.5 1.9 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport DUF2207 PF09972.9 OAG05118.1 - 0.34 9.6 4.6 0.5 9.1 1.1 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) EamA PF00892.20 OAG05118.1 - 0.99 9.6 24.9 0.056 13.6 1.9 3.3 2 2 1 3 3 3 0 EamA-like transporter family Multi_Drug_Res PF00893.19 OAG05118.1 - 1.2 9.8 9.5 30 5.4 0.1 3.0 2 1 0 2 2 2 0 Small Multidrug Resistance protein DUF4131 PF13567.6 OAG05118.1 - 3.8 7.1 16.4 5.5 6.6 0.8 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4131) HlyIII PF03006.20 OAG05118.1 - 6.6 6.4 12.3 0.56 9.9 3.8 2.3 1 1 1 2 2 2 0 Haemolysin-III related fn3_2 PF16893.5 OAG05119.1 - 4.7e-39 132.4 0.0 7.3e-39 131.8 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 OAG05119.1 - 3.6e-24 84.4 0.5 5.8e-24 83.8 0.5 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 OAG05119.1 - 6.5e-15 54.8 0.0 1.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 OAG05119.1 - 3.1e-10 40.3 0.0 5.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 OAG05119.1 - 5.4e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 OAG05119.1 - 0.00029 21.2 0.0 0.00062 20.1 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 OAG05119.1 - 0.00048 20.4 0.0 0.0017 18.7 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain DUF1297 PF06973.12 OAG05119.1 - 0.0058 16.2 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) Totivirus_coat PF05518.11 OAG05119.1 - 3.6 5.5 6.2 5 5.0 6.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein Melibiase_2 PF16499.5 OAG05120.1 - 6.2e-56 189.7 1.9 1e-55 188.9 1.9 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OAG05120.1 - 2e-13 50.2 0.2 6.1e-13 48.7 0.1 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG05120.1 - 1.4e-05 24.3 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 OAG05120.1 - 0.00033 20.0 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 DUF1906 PF08924.11 OAG05120.1 - 0.07 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Ank_4 PF13637.6 OAG05121.1 - 0.013 16.0 0.1 0.29 11.8 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG05121.1 - 0.029 15.0 0.0 0.55 10.9 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) LRS4 PF10422.9 OAG05121.1 - 0.056 13.0 0.6 0.085 12.4 0.6 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 NmrA PF05368.13 OAG05122.1 - 3.9e-30 105.2 0.7 4.8e-30 104.8 0.7 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG05122.1 - 3.5e-16 59.6 0.3 6.3e-14 52.3 0.0 2.2 1 1 0 2 2 2 2 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG05122.1 - 5.9e-06 26.6 0.1 9.9e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG05122.1 - 0.0023 17.5 0.2 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG05122.1 - 0.0032 17.6 0.1 0.0083 16.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG05122.1 - 0.014 15.8 0.2 0.073 13.5 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding DapB_N PF01113.20 OAG05122.1 - 0.061 13.4 1.6 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 OAG05122.1 - 0.14 13.0 0.1 0.76 10.6 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1752 PF08550.10 OAG05123.1 - 0.28 11.0 1.8 14 5.6 0.2 2.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) Methyltransf_2 PF00891.18 OAG05125.1 - 2.5e-10 40.0 0.0 3.1e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OAG05125.1 - 8.2e-05 22.2 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAG05125.1 - 0.0001 22.9 0.0 0.00016 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG05125.1 - 0.056 14.1 0.0 0.086 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAG05125.1 - 0.065 14.0 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 OAG05125.1 - 0.096 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase 4HBT PF03061.22 OAG05126.1 - 5.8e-06 26.6 0.2 5.2e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 Thioesterase superfamily BRCT PF00533.26 OAG05127.1 - 1.1e-17 64.1 0.7 1.5e-07 31.7 0.1 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG05127.1 - 8.3e-08 32.1 0.1 0.0047 16.9 0.0 2.4 2 0 0 2 2 2 2 twin BRCT domain Glyco_trans_1_4 PF13692.6 OAG05127.1 - 0.046 14.2 0.1 7.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 CDC45 PF02724.14 OAG05127.1 - 0.23 9.7 2.3 0.26 9.5 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_4 PF13894.6 OAG05128.1 - 0.0085 16.9 3.0 0.098 13.5 0.5 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger RRP36 PF06102.12 OAG05128.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.0 3 0 0 3 3 3 0 rRNA biogenesis protein RRP36 cobW PF02492.19 OAG05129.1 - 1.3e-32 112.8 0.0 1.6e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAG05129.1 - 4e-05 22.7 0.1 0.0067 15.4 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OAG05129.1 - 0.0023 18.0 0.0 0.0057 16.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OAG05129.1 - 0.047 14.2 0.0 0.06 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG05129.1 - 0.057 14.0 0.0 0.088 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 OAG05129.1 - 0.087 12.6 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 OAG05129.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG05129.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 OAG05129.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 OAG05129.1 - 0.14 12.0 0.1 3.7 7.4 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 OAG05129.1 - 0.15 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 OAG05129.1 - 0.17 11.9 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TsaE PF02367.17 OAG05129.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OAG05129.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 OAG05129.1 - 0.18 10.8 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CtaG_Cox11 PF04442.14 OAG05130.1 - 4.4e-60 202.1 0.0 6.4e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 zf-HIT PF04438.16 OAG05131.1 - 3.5e-10 39.6 11.2 5.2e-10 39.0 11.2 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 OAG05131.1 - 0.0053 16.8 7.2 0.008 16.2 7.2 1.2 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OAG05131.1 - 0.45 10.9 7.5 0.89 9.9 7.5 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 OAG05131.1 - 1.4 9.1 7.4 1.1 9.4 5.8 1.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-B_box PF00643.24 OAG05131.1 - 2 8.6 6.6 3.2 8.0 6.6 1.2 1 0 0 1 1 1 0 B-box zinc finger FoP_duplication PF13865.6 OAG05131.1 - 2.1 9.0 14.6 3.9 8.1 14.6 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ABC_membrane PF00664.23 OAG05133.1 - 2.1e-102 342.4 38.5 3.6e-55 187.5 13.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG05133.1 - 3.7e-62 208.9 1.6 4.1e-30 105.1 0.0 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OAG05133.1 - 3.2e-10 39.8 8.5 0.00014 21.4 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG05133.1 - 2.2e-06 27.3 8.2 0.037 13.8 0.1 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG05133.1 - 2e-05 24.6 0.1 0.41 10.5 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAG05133.1 - 4.7e-05 23.8 6.1 0.1 13.0 0.2 3.4 3 2 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 OAG05133.1 - 6e-05 22.8 0.5 0.14 11.9 0.2 3.4 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAG05133.1 - 0.00014 21.7 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 OAG05133.1 - 0.0012 17.7 0.2 0.042 12.6 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 OAG05133.1 - 0.0019 18.4 0.8 0.43 10.8 0.0 3.2 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG05133.1 - 0.0024 17.7 0.2 0.5 10.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OAG05133.1 - 0.012 15.7 0.0 7 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAG05133.1 - 0.015 15.9 0.0 7 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAG05133.1 - 0.023 13.8 0.0 2.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 OAG05133.1 - 0.023 14.8 0.0 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 OAG05133.1 - 0.026 13.8 0.0 0.58 9.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 OAG05133.1 - 0.028 14.6 1.5 18 5.7 0.2 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAG05133.1 - 0.051 13.6 0.3 26 4.8 0.0 3.6 4 1 0 4 4 3 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 OAG05133.1 - 0.068 12.3 0.0 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.20 OAG05133.1 - 0.083 12.8 0.4 12 5.7 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_7 PF12775.7 OAG05133.1 - 0.17 11.4 0.0 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FAD_binding_2 PF00890.24 OAG05134.1 - 4.7e-118 394.9 6.9 6.2e-118 394.5 6.9 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAG05134.1 - 3.9e-39 133.6 1.9 6.3e-39 132.9 1.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 OAG05134.1 - 4.6e-06 26.1 0.7 0.0016 17.7 0.2 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG05134.1 - 0.00021 20.6 0.5 0.05 12.8 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 OAG05134.1 - 0.0016 17.8 0.7 0.0029 16.9 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OAG05134.1 - 0.0023 17.1 3.5 0.11 11.6 2.9 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG05134.1 - 0.0059 15.7 0.1 0.0097 15.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAG05134.1 - 0.014 15.0 2.9 0.29 10.7 2.5 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG05134.1 - 0.45 9.2 4.6 0.39 9.4 1.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAG05134.1 - 1.4 8.1 4.9 1.2 8.3 1.9 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Tetraspanin PF00335.20 OAG05135.1 - 2e-06 27.7 0.2 4.2e-06 26.6 0.2 1.5 1 1 0 1 1 1 1 Tetraspanin family EF-hand_7 PF13499.6 OAG05137.1 - 5e-10 39.7 1.3 1.3e-06 28.7 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG05137.1 - 1.1e-07 31.2 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAG05137.1 - 1.2e-07 30.8 0.0 0.0075 15.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OAG05137.1 - 3.3e-07 29.5 0.0 0.0045 16.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OAG05137.1 - 0.0046 16.8 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Pam16 PF03656.13 OAG05137.1 - 0.041 13.9 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Pam16 Diedel PF13164.6 OAG05137.1 - 0.3 11.5 18.8 0.53 10.8 18.8 1.4 1 0 0 1 1 1 0 Diedel ICMT PF04140.14 OAG05138.1 - 2.4e-15 56.7 2.6 2.5e-11 43.8 0.1 3.0 2 1 1 3 3 3 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAG05138.1 - 9.6e-08 32.4 0.4 9.6e-08 32.4 0.4 3.3 4 0 0 4 4 4 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 OAG05138.1 - 6.1e-05 22.0 0.6 8.7e-05 21.5 0.6 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OAG05138.1 - 0.0082 15.7 0.8 0.031 13.8 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAG05138.1 - 0.4 10.6 5.3 0.7 9.9 0.4 2.7 2 1 1 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase Redoxin PF08534.10 OAG05139.1 - 7.6e-36 123.0 0.0 8.5e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG05139.1 - 5.5e-08 32.8 0.0 5.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Lipase_GDSL_2 PF13472.6 OAG05139.1 - 0.028 14.8 0.0 0.041 14.3 0.0 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF1348 PF07080.11 OAG05140.1 - 5.5e-60 201.0 7.0 6.3e-60 200.8 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 OAG05140.1 - 3.8e-06 27.5 0.2 5.1e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG05140.1 - 0.00069 20.0 0.1 0.0042 17.5 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) Robl_LC7 PF03259.17 OAG05141.1 - 1.2e-07 31.4 0.0 4.7e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.8 OAG05142.1 - 2.7e-28 98.5 0.3 2.7e-28 98.5 0.3 2.6 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Dsh_C PF12316.8 OAG05142.1 - 0.054 13.9 1.2 0.083 13.3 1.2 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF262 PF03235.14 OAG05143.1 - 5.8e-09 36.4 0.1 2.3e-08 34.5 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function DUF262 SGL PF08450.12 OAG05144.1 - 2.3e-05 24.1 0.4 0.00047 19.8 0.0 2.3 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Trp_syntA PF00290.20 OAG05145.1 - 2.4e-94 315.0 0.0 4.4e-94 314.2 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 OAG05145.1 - 1e-46 159.7 1.2 1.7e-46 159.0 1.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SPX PF03105.19 OAG05145.1 - 1.1e-37 130.8 5.3 1.4e-23 84.5 3.0 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 OAG05145.1 - 7.4e-32 111.0 44.2 1e-31 110.5 44.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OAG05145.1 - 1.2e-24 87.0 41.1 1.2e-24 87.0 41.1 2.0 2 1 0 2 2 2 1 Citrate transporter FxsA PF04186.13 OAG05145.1 - 0.72 10.0 11.1 0.086 13.0 3.3 3.0 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein Zn_clus PF00172.18 OAG05146.1 - 9.2e-08 32.1 6.7 1.5e-07 31.4 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG05149.1 - 4.9e-26 91.4 0.0 2.1e-24 86.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05149.1 - 2.2e-14 53.6 0.0 2.1e-13 50.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG05149.1 - 1.1e-09 38.4 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG05149.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG05149.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAG05149.1 - 0.15 11.1 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SGL PF08450.12 OAG05150.1 - 1e-07 31.8 0.1 7.1e-05 22.5 0.0 2.6 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region nec1 PF10379.9 OAG05150.1 - 0.022 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Virulence protein nec1 NUC173 PF08161.12 OAG05151.1 - 2.1e-82 275.7 0.3 5e-78 261.4 0.0 2.8 2 0 0 2 2 2 2 NUC173 domain MMS19_C PF12460.8 OAG05151.1 - 0.00014 21.1 0.3 0.00014 21.1 0.3 4.3 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 OAG05151.1 - 0.014 15.6 2.2 20 5.8 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat DUF359 PF04019.12 OAG05151.1 - 0.046 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF359) HEAT_2 PF13646.6 OAG05151.1 - 0.29 11.6 8.1 3.7 8.0 1.6 5.2 3 2 2 5 5 5 0 HEAT repeats TT_ORF2 PF02957.15 OAG05151.1 - 3.9 8.4 5.6 18 6.3 0.9 3.1 2 0 0 2 2 2 0 TT viral ORF2 HEAT_EZ PF13513.6 OAG05151.1 - 9.4 6.9 8.4 26 5.4 0.1 4.0 5 0 0 5 5 5 0 HEAT-like repeat DOCK_N PF16172.5 OAG05152.1 - 1.2e-108 363.4 0.0 2.2e-108 362.6 0.0 1.4 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 OAG05152.1 - 9.2e-38 130.2 7.1 3.7e-37 128.2 7.1 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OAG05152.1 - 4.4e-34 118.0 0.0 9.7e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 OAG05152.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG05152.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain FANCI_S2 PF14676.6 OAG05152.1 - 0.17 12.2 0.8 0.54 10.6 0.8 1.8 1 0 0 1 1 1 0 FANCI solenoid 2 MA-Mit PF09245.10 OAG05152.1 - 0.19 11.2 0.7 1.4 8.3 0.2 2.3 2 0 0 2 2 2 0 Mycoplasma arthritidis-derived mitogen COesterase PF00135.28 OAG05153.1 - 1.9e-68 231.6 3.7 7.7e-68 229.6 3.7 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG05153.1 - 5.4e-06 26.4 0.1 7.1e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG05153.1 - 0.025 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1674 PF07896.12 OAG05154.1 - 3.9e-17 62.5 2.6 9.1e-17 61.3 2.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) AA_permease_2 PF13520.6 OAG05155.1 - 7.7e-64 216.1 52.9 9.6e-64 215.8 52.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG05155.1 - 2.9e-20 72.3 45.0 3.7e-20 72.0 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease F-box-like_2 PF13013.6 OAG05156.1 - 0.021 14.8 0.1 0.1 12.6 0.1 2.2 1 1 0 1 1 1 0 F-box-like domain UBM PF14377.6 OAG05156.1 - 0.072 12.6 2.2 0.1 12.1 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin binding region DUF2407_C PF13373.6 OAG05157.1 - 0.078 13.1 0.3 0.11 12.7 0.3 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain NAD_binding_6 PF08030.12 OAG05159.1 - 1.4e-20 74.0 0.0 4.6e-20 72.3 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAG05159.1 - 1.6e-19 70.2 9.2 3.9e-19 69.0 9.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG05159.1 - 6.5e-13 48.7 0.0 2.3e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAG05159.1 - 3.5e-06 27.6 0.0 0.077 13.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OAG05159.1 - 0.73 10.4 14.0 0.082 13.5 2.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) KAR9 PF08580.10 OAG05160.1 - 2.8 6.4 5.0 3.1 6.2 5.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Glyoxalase PF00903.25 OAG05162.1 - 4.8e-10 39.7 0.0 6.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAG05162.1 - 5.3e-05 23.1 0.0 6.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 OAG05162.1 - 0.0017 19.1 0.0 0.002 18.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Pkinase PF00069.25 OAG05163.1 - 6.2e-41 140.5 0.0 9.9e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG05163.1 - 4.8e-25 88.3 0.0 9.1e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_10 PF13374.6 OAG05163.1 - 2.1e-05 24.2 0.8 0.0011 18.7 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG05163.1 - 0.0021 18.7 0.1 0.52 11.3 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG05163.1 - 0.0035 17.6 10.6 0.3 11.4 0.1 4.9 2 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG05163.1 - 0.006 17.1 0.1 4.3 7.9 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG05163.1 - 0.058 14.1 0.3 0.67 10.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG05163.1 - 0.073 12.9 4.5 0.88 9.5 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF5377 PF17347.2 OAG05163.1 - 0.077 13.4 0.0 0.71 10.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5377) TPR_2 PF07719.17 OAG05163.1 - 0.1 12.7 0.1 0.1 12.7 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG05163.1 - 0.13 12.5 6.7 4.3 7.6 0.0 3.9 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OAG05163.1 - 0.26 11.6 0.7 3.9 7.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat WH2 PF02205.20 OAG05165.1 - 1.2e-06 28.1 0.5 2.6e-06 27.1 0.5 1.6 1 0 0 1 1 1 1 WH2 motif WH1 PF00568.23 OAG05166.1 - 3.9e-23 81.5 0.1 4.3e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 WH1 domain DUF4962 PF16332.5 OAG05166.1 - 0.078 11.5 0.0 0.096 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Mit_KHE1 PF10173.9 OAG05167.1 - 0.039 14.0 0.1 0.039 14.0 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related PAC2 PF09754.9 OAG05167.1 - 0.058 13.4 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 PAC2 family Ald_Xan_dh_C2 PF02738.18 OAG05168.1 - 8.8e-206 684.6 1.6 1.3e-205 684.1 1.6 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OAG05168.1 - 4.3e-46 156.7 0.0 8.4e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 OAG05168.1 - 1.1e-33 115.4 0.1 6.9e-33 112.9 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 OAG05168.1 - 7e-32 110.1 0.0 1.7e-31 108.8 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 OAG05168.1 - 1.6e-29 101.8 0.1 3.4e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 OAG05168.1 - 1e-07 31.8 0.1 1e-07 31.8 0.1 3.1 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain TIP49 PF06068.13 OAG05169.1 - 4.1e-161 536.0 0.0 4.9e-161 535.8 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAG05169.1 - 2.2e-18 66.2 0.0 4.7e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OAG05169.1 - 6.8e-11 42.7 0.1 2.6e-07 31.1 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG05169.1 - 5.1e-09 36.1 0.1 3.1e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG05169.1 - 2.5e-05 24.5 0.2 0.24 11.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG05169.1 - 3e-05 24.5 0.4 0.00063 20.2 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OAG05169.1 - 5.9e-05 23.4 0.8 0.063 13.6 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAG05169.1 - 0.00049 20.1 0.1 0.2 11.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAG05169.1 - 0.0014 18.9 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAG05169.1 - 0.0034 17.1 0.2 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 OAG05169.1 - 0.0064 15.8 0.4 0.014 14.7 0.3 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 OAG05169.1 - 0.025 14.2 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG05169.1 - 0.026 13.9 0.3 0.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 OAG05169.1 - 0.041 13.2 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 OAG05169.1 - 0.045 13.1 0.4 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 OAG05169.1 - 0.065 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 OAG05169.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OAG05169.1 - 0.078 12.7 0.3 0.61 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG05169.1 - 0.11 12.0 0.2 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 OAG05169.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 OAG05170.1 - 1.4e-34 118.0 1.6 1.3e-17 63.6 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 OAG05170.1 - 1.1e-19 70.4 0.8 4e-19 68.5 0.1 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Utp12 PF04003.12 OAG05171.1 - 3.5e-23 82.0 0.2 4.9e-23 81.5 0.2 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family BUD22 PF09073.10 OAG05171.1 - 6.5 6.0 34.4 0.24 10.7 22.0 2.2 2 0 0 2 2 2 0 BUD22 TPR_12 PF13424.6 OAG05172.1 - 7.7e-58 192.7 29.5 9.1e-18 64.3 0.9 5.5 3 1 4 7 7 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 OAG05172.1 - 3.6e-53 176.1 17.6 7.6e-13 47.9 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG05172.1 - 1.9e-14 52.5 9.9 0.00074 19.4 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG05172.1 - 2.2e-12 46.2 18.0 0.0016 18.2 0.1 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat HET PF06985.11 OAG05172.1 - 2.6e-10 40.8 6.5 9.7e-08 32.5 0.1 3.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_16 PF13432.6 OAG05172.1 - 8.3e-08 32.8 7.9 0.049 14.3 0.1 5.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG05172.1 - 1.3e-07 31.1 12.8 0.54 10.5 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 OAG05172.1 - 2.3e-07 30.8 0.2 1.1 10.1 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAG05172.1 - 3.7e-07 29.6 0.0 6.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 OAG05172.1 - 4.7e-07 29.9 0.1 8.5e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.6 OAG05172.1 - 6.2e-07 29.1 3.9 3.5 8.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAG05172.1 - 3.5e-06 27.5 3.3 1.1e-05 25.8 0.8 2.9 1 1 0 2 2 2 1 AAA ATPase domain TPR_MalT PF17874.1 OAG05172.1 - 1.3e-05 24.8 7.4 0.00022 20.7 2.8 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 OAG05172.1 - 2.4e-05 24.7 12.9 0.49 11.3 0.0 6.8 6 1 1 7 7 6 1 Tetratricopeptide repeat ATPase_2 PF01637.18 OAG05172.1 - 3.9e-05 23.7 0.0 0.00016 21.7 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ANAPC3 PF12895.7 OAG05172.1 - 0.00015 21.9 0.1 0.22 11.8 0.0 4.0 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OAG05172.1 - 0.00016 21.8 0.1 44 4.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 OAG05172.1 - 0.00069 19.9 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Atu4866 PF11512.8 OAG05172.1 - 0.011 16.1 1.4 44 4.5 0.0 4.3 4 0 0 4 4 4 0 Agrobacterium tumefaciens protein Atu4866 ResIII PF04851.15 OAG05172.1 - 0.028 14.4 0.0 0.084 12.9 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TPR_19 PF14559.6 OAG05172.1 - 0.058 13.9 6.4 0.56 10.8 0.2 3.8 4 1 1 5 5 4 0 Tetratricopeptide repeat ATPase PF06745.13 OAG05172.1 - 0.19 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 KaiC TPR_11 PF13414.6 OAG05172.1 - 0.44 10.3 2.3 92 2.8 0.1 4.3 5 0 0 5 5 4 0 TPR repeat DUF1897 PF09005.10 OAG05172.1 - 1.7 8.2 6.9 15 5.1 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) DUF3933 PF13069.6 OAG05173.1 - 0.057 13.3 0.0 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) bZIP_Maf PF03131.17 OAG05173.1 - 0.071 13.6 0.2 0.26 11.8 0.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor ADH_N PF08240.12 OAG05174.1 - 4.5e-25 87.7 2.3 7.1e-25 87.0 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG05174.1 - 4.5e-13 49.3 0.0 1.5e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG05175.1 - 7.4e-29 99.8 0.4 1.5e-28 98.8 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG05175.1 - 8.1e-28 97.0 0.1 1.5e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG05175.1 - 1.5e-09 39.0 0.0 2.5e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG05175.1 - 1.3e-07 31.3 0.1 2.4e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 OAG05175.1 - 0.0036 17.7 0.2 0.0061 17.0 0.2 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OAG05175.1 - 0.0045 17.2 0.1 0.008 16.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG05175.1 - 0.016 14.7 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG05175.1 - 0.032 14.3 0.0 0.072 13.1 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 OAG05175.1 - 0.036 14.5 0.0 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAG05175.1 - 0.038 13.2 0.1 0.068 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 OAG05175.1 - 0.039 14.5 0.1 0.076 13.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 OAG05175.1 - 0.043 14.1 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 OAG05175.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG05175.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MARVEL PF01284.23 OAG05176.1 - 0.018 15.1 16.4 0.032 14.3 16.3 1.4 1 1 0 1 1 1 0 Membrane-associating domain CENP-S PF15630.6 OAG05177.1 - 2.2e-31 108.0 0.0 2.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAG05177.1 - 4.4e-09 36.4 0.0 4.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF848 PF05852.11 OAG05177.1 - 0.032 14.4 0.2 0.034 14.2 0.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TFIID-18kDa PF02269.16 OAG05177.1 - 0.033 14.2 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.15 OAG05177.1 - 0.096 12.8 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PGA2 PF07543.12 OAG05178.1 - 4.4e-39 133.6 1.4 5e-39 133.4 1.4 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 MCM6_C PF18263.1 OAG05178.1 - 0.026 14.8 3.1 2.3 8.5 1.4 2.1 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain DUF1479 PF07350.12 OAG05178.1 - 0.045 12.5 0.0 0.062 12.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1479) LPMO_10 PF03067.15 OAG05179.1 - 0.1 13.2 0.3 0.18 12.4 0.3 1.5 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Condensation PF00668.20 OAG05180.1 - 2.3e-13 49.7 0.1 3e-09 36.1 0.0 2.0 1 1 1 2 2 2 2 Condensation domain HTH_15 PF12324.8 OAG05181.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Herpes_LMP1 PF05297.11 OAG05182.1 - 0.27 10.4 1.2 0.29 10.3 1.2 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Proteasome PF00227.26 OAG05183.1 - 5.5e-57 192.3 0.0 1.3e-32 112.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OAG05183.1 - 9.2e-11 41.2 0.1 3.2e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 OAG05183.1 - 0.12 11.0 0.4 8 5.1 0.0 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Ribonuclease_3 PF00636.26 OAG05184.1 - 9.8e-34 116.1 0.0 5.1e-16 59.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 OAG05184.1 - 5.2e-24 84.2 0.1 1.8e-22 79.3 0.0 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 OAG05184.1 - 1.1e-21 77.3 0.0 3.2e-07 30.6 0.0 4.0 3 1 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.29 OAG05184.1 - 3.8e-17 62.6 0.0 8.7e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG05184.1 - 8.5e-17 61.5 0.0 2.2e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG05184.1 - 4.9e-14 52.7 0.0 8.1e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OAG05184.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PhoH PF02562.16 OAG05184.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 OAG05184.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1035 PF06281.12 OAG05184.1 - 0.32 11.0 1.3 6.5 6.8 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) TFR_dimer PF04253.15 OAG05185.1 - 8e-24 84.1 0.0 1.5e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG05185.1 - 2.6e-20 72.9 0.0 4.8e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG05185.1 - 2.5e-08 33.8 0.1 7.4e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG05185.1 - 0.077 12.7 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 GAS2 PF02187.17 OAG05186.1 - 5.7e-06 26.3 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain BING4CT PF08149.11 OAG05187.1 - 8.6e-36 121.6 0.3 1.8e-32 111.0 0.0 3.3 4 0 0 4 4 4 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 OAG05187.1 - 3.6e-06 27.2 0.1 0.88 9.9 0.0 4.7 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG05187.1 - 8.5e-05 23.3 0.0 0.0037 18.1 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat CATSPERD PF15020.6 OAG05187.1 - 0.17 10.1 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta HET PF06985.11 OAG05188.1 - 1.1e-05 25.8 0.6 1.2e-05 25.7 0.6 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_L17 PF01196.19 OAG05188.1 - 0.1 13.5 0.0 0.11 13.4 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L17 DUF3328 PF11807.8 OAG05190.1 - 5.5e-42 144.0 0.2 6.3e-42 143.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cyt-b5 PF00173.28 OAG05191.1 - 5.4e-10 39.3 0.0 8.1e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mus7 PF09462.10 OAG05193.1 - 6.8e-120 401.8 0.1 8.8e-120 401.4 0.1 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family DUF2753 PF10952.8 OAG05193.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) PPTA PF01239.22 OAG05195.1 - 4.2e-40 134.4 21.2 5.3e-08 32.3 0.1 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.6 OAG05195.1 - 0.53 10.1 4.3 5.9 6.7 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) ANAPC4_WD40 PF12894.7 OAG05196.1 - 3e-09 37.0 0.0 0.041 14.2 0.0 4.9 4 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG05196.1 - 4.4e-06 27.3 3.9 0.0013 19.5 0.0 5.5 7 0 0 7 7 7 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OAG05196.1 - 0.024 13.7 0.0 0.81 8.7 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region Ribosomal_S6e PF01092.19 OAG05197.1 - 7.8e-58 193.9 0.1 1.4e-57 193.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Atg14 PF10186.9 OAG05197.1 - 3.7 6.6 7.8 4.7 6.2 7.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Calcipressin PF04847.12 OAG05198.1 - 1.1e-41 142.7 0.2 1.4e-41 142.3 0.2 1.1 1 0 0 1 1 1 1 Calcipressin RNA_pol_A_bac PF01000.26 OAG05200.1 - 2.6e-30 105.0 0.0 3.9e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAG05200.1 - 2.3e-17 62.2 0.0 2.9e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GrpE PF01025.19 OAG05201.1 - 7.6e-45 152.5 2.2 9.5e-45 152.2 2.2 1.0 1 0 0 1 1 1 1 GrpE Peptidase_S49 PF01343.18 OAG05201.1 - 0.053 13.5 1.0 0.074 13.0 1.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 PrpF PF04303.13 OAG05202.1 - 4.7e-64 216.7 0.3 5.6e-64 216.4 0.3 1.0 1 0 0 1 1 1 1 PrpF protein Toast_rack_N PF17115.5 OAG05202.1 - 0.17 12.2 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of toast_rack, DUF2154 MFS_1 PF07690.16 OAG05203.1 - 1.1e-37 129.9 29.9 1.1e-37 129.9 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG05203.1 - 3.8e-09 35.9 8.1 3.8e-09 35.9 8.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG05203.1 - 9.1e-06 25.2 3.6 9.1e-06 25.2 3.6 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB POP1 PF06978.11 OAG05204.1 - 6e-66 222.3 11.9 9.7e-66 221.7 11.9 1.3 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OAG05204.1 - 1.7e-32 111.6 0.7 1.7e-32 111.6 0.7 2.7 3 0 0 3 3 3 1 POPLD (NUC188) domain Mito_carr PF00153.27 OAG05205.1 - 1.9e-51 171.9 1.2 1e-16 60.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 OAG05206.1 - 8.3e-48 163.0 0.3 2.3e-27 96.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OAG05206.1 - 9.6e-24 83.6 0.0 2.5e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Uds1 PF15456.6 OAG05209.1 - 1.9e-28 99.2 9.0 1.9e-28 99.2 9.0 1.8 1 1 1 2 2 2 1 Up-regulated During Septation Stathmin PF00836.19 OAG05209.1 - 0.054 13.5 0.4 0.054 13.5 0.4 3.0 3 0 0 3 3 3 0 Stathmin family APG6_N PF17675.1 OAG05209.1 - 4.4 7.8 9.8 0.15 12.6 2.5 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Pribosyltran_N PF13793.6 OAG05210.1 - 1.1e-44 151.0 0.2 6.3e-44 148.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAG05210.1 - 3.8e-41 141.1 1.5 1.4e-35 123.0 1.6 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAG05210.1 - 2.3e-17 63.0 1.7 5.3e-16 58.5 1.0 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG05210.1 - 0.0016 17.9 0.2 0.003 17.0 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Mob1_phocein PF03637.17 OAG05211.1 - 3.3e-71 238.8 0.0 4.9e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family DnaJ PF00226.31 OAG05213.1 - 7.6e-09 35.6 0.2 4.5e-08 33.1 0.2 2.1 1 1 0 1 1 1 1 DnaJ domain FAD_binding_7 PF03441.14 OAG05214.1 - 4.8e-45 153.5 0.2 8.5e-45 152.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG05214.1 - 8.8e-12 45.3 0.3 3.5e-10 40.1 0.3 2.5 1 1 0 1 1 1 1 DNA photolyase Pyridoxal_deC PF00282.19 OAG05215.1 - 2.9e-59 200.7 0.0 4e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAG05215.1 - 3.5e-05 23.0 0.0 6.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Fasciclin PF02469.22 OAG05216.1 - 3.2e-43 147.0 0.0 2e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 OAG05216.1 - 0.046 13.9 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 DUF3984 PF13136.6 OAG05217.1 - 0.012 15.1 10.0 0.017 14.5 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) SOG2 PF10428.9 OAG05217.1 - 4.7 6.3 13.3 6.6 5.8 13.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein HET PF06985.11 OAG05218.1 - 3.3e-24 85.9 0.0 8.3e-24 84.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GST_N_3 PF13417.6 OAG05219.1 - 1.1e-13 51.4 0.1 1.8e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG05219.1 - 5.2e-13 49.1 0.0 1.3e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG05219.1 - 1e-11 45.0 0.1 1.5e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG05219.1 - 1.5e-05 24.9 0.0 4.1e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG05219.1 - 0.00033 20.8 0.0 0.00075 19.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG05219.1 - 0.00041 20.5 0.0 0.00081 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG05219.1 - 0.018 15.6 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4050 PF13259.6 OAG05220.1 - 8.5e-47 159.8 1.7 5.5e-28 98.5 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) Glyco_hydro_63 PF03200.16 OAG05221.1 - 1.2e-05 24.3 9.0 6.7e-05 21.8 4.0 3.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain p450 PF00067.22 OAG05222.1 - 4.8e-50 170.7 0.0 5.5e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4746 PF15928.5 OAG05223.1 - 0.22 10.9 3.9 0.27 10.6 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 OAG05223.1 - 2.3 6.4 6.0 2.2 6.5 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAG05223.1 - 5 5.2 9.9 5.6 5.0 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family Sgf11 PF08209.11 OAG05224.1 - 4.3e-12 45.4 1.5 1.1e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) DUF2986 PF11661.8 OAG05224.1 - 0.044 14.3 3.3 0.044 14.3 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) zf_UBZ PF18439.1 OAG05224.1 - 0.12 12.0 1.2 0.33 10.6 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-TFIIB PF13453.6 OAG05224.1 - 0.61 9.5 3.3 0.33 10.3 0.2 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C2HC_2 PF13913.6 OAG05224.1 - 1.9 8.5 9.9 0.38 10.7 2.0 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type His_Phos_1 PF00300.22 OAG05226.1 - 2e-25 89.7 0.0 2.8e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Zn_clus PF00172.18 OAG05227.1 - 0.00016 21.7 13.7 0.00016 21.7 13.7 3.5 5 0 0 5 5 5 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 OAG05228.1 - 5.6e-58 196.9 1.5 7e-58 196.5 1.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAG05229.1 - 5.5e-22 78.2 16.1 7.9e-22 77.7 16.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.6 OAG05229.1 - 0.14 12.2 0.2 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Pkinase PF00069.25 OAG05230.1 - 6.2e-30 104.4 0.0 1.1e-29 103.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG05230.1 - 1.4e-20 73.7 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_ab PF00006.25 OAG05231.1 - 1.8e-67 227.1 0.0 2.5e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAG05231.1 - 3.2e-14 53.2 0.5 6.3e-14 52.3 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF561 PF04481.12 OAG05231.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) LIM_bind PF01803.16 OAG05232.1 - 5.2e-57 193.2 3.8 5.2e-57 193.2 3.8 5.4 3 1 1 4 4 4 1 LIM-domain binding protein Methyltransf_17 PF12692.7 OAG05232.1 - 0.38 10.7 5.4 0.089 12.8 1.7 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase RAMP4 PF06624.12 OAG05232.1 - 2.7 8.1 7.0 30 4.8 1.6 3.7 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 tRNA-synt_1 PF00133.22 OAG05233.1 - 1.9e-34 118.9 0.0 3.6e-27 94.9 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG05233.1 - 1.4e-14 54.3 2.2 2e-14 53.8 0.4 2.2 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAG05233.1 - 3.8e-13 49.0 0.0 3.2e-08 32.7 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OAG05233.1 - 2.4e-09 37.0 0.1 8.1e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain YxiJ PF14176.6 OAG05233.1 - 0.039 14.5 0.1 13 6.4 0.0 2.8 2 0 0 2 2 2 0 YxiJ-like protein GFO_IDH_MocA PF01408.22 OAG05236.1 - 1.2e-25 90.7 0.1 2.1e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG05236.1 - 0.00043 20.3 0.0 0.00088 19.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.6 OAG05236.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 OAG05236.1 - 0.04 14.2 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N PF08240.12 OAG05237.1 - 1.8e-27 95.4 0.8 1.8e-27 95.4 0.8 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG05237.1 - 1.2e-16 60.9 0.7 1.2e-16 60.9 0.7 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG05237.1 - 1.8e-10 40.7 1.1 4.2e-06 26.4 0.0 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus Cpn10 PF00166.21 OAG05237.1 - 0.0026 17.8 0.1 0.0078 16.2 0.1 1.8 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit AlaDh_PNT_C PF01262.21 OAG05237.1 - 0.012 14.9 1.9 0.023 14.0 1.9 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 OAG05237.1 - 0.037 13.4 0.3 0.08 12.3 0.3 1.5 1 0 0 1 1 1 0 ThiF family ADH_zinc_N_2 PF13602.6 OAG05237.1 - 0.043 14.9 0.0 0.15 13.1 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG05237.1 - 0.047 13.3 1.5 0.076 12.6 0.9 1.8 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG05237.1 - 0.094 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cu_bind_like PF02298.17 OAG05237.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Plastocyanin-like domain adh_short_C2 PF13561.6 OAG05238.1 - 1.4e-56 191.6 0.1 1.9e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG05238.1 - 1.5e-53 181.1 0.1 1.9e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG05238.1 - 3e-14 53.3 0.4 5.6e-14 52.5 0.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG05238.1 - 8.4e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 OAG05238.1 - 0.0018 18.0 0.0 0.067 12.9 0.0 2.5 2 1 1 3 3 3 1 Starch synthase catalytic domain PALP PF00291.25 OAG05238.1 - 0.0051 16.3 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 OAG05238.1 - 0.023 14.3 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG05238.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG05238.1 - 0.05 12.7 0.1 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 OAG05238.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Myosin_N PF02736.19 OAG05238.1 - 0.13 12.1 0.1 0.34 10.8 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain NAD_binding_7 PF13241.6 OAG05238.1 - 0.15 12.5 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Aldo_ket_red PF00248.21 OAG05239.1 - 5.7e-41 140.6 0.0 1.2e-38 133.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MIOX PF05153.15 OAG05240.1 - 1.5e-121 404.7 2.4 2e-121 404.3 2.4 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 OAG05240.1 - 0.15 12.3 0.3 0.65 10.2 0.0 2.1 3 0 0 3 3 3 0 HD domain PLA2G12 PF06951.11 OAG05241.1 - 4.7e-05 23.4 4.1 7.6e-05 22.7 4.1 1.3 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) HET PF06985.11 OAG05243.1 - 8.6e-16 58.6 0.2 9.1e-16 58.5 0.2 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GN3L_Grn1 PF08701.11 OAG05246.1 - 0.036 14.1 0.3 0.057 13.5 0.3 1.3 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase DUF4887 PF16228.5 OAG05246.1 - 0.37 11.0 5.5 0.49 10.5 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Chorismate_bind PF00425.18 OAG05248.1 - 1.2e-91 306.9 0.0 9.2e-91 304.0 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 OAG05248.1 - 3.8e-27 95.2 0.0 1.9e-23 83.2 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region CFEM PF05730.11 OAG05249.1 - 1.1e-14 54.3 7.7 1.3e-14 54.0 7.7 1.1 1 0 0 1 1 1 1 CFEM domain Aldo_ket_red PF00248.21 OAG05250.1 - 2.2e-44 151.8 0.0 2.5e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4246 PF14033.6 OAG05251.1 - 5.8e-167 556.4 0.2 6.8e-167 556.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 OAG05251.1 - 0.0041 17.5 0.0 0.014 15.8 0.0 1.8 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OAG05251.1 - 0.097 13.6 0.0 0.27 12.1 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily COesterase PF00135.28 OAG05252.1 - 1.1e-86 291.8 0.0 1.3e-86 291.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG05252.1 - 8.5e-06 25.8 0.0 3.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_2 PF00703.21 OAG05253.1 - 6.9e-16 58.9 5.4 2.1e-14 54.1 0.1 3.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 DUF4982 PF16355.5 OAG05253.1 - 2.1e-15 56.4 0.0 2.6e-14 52.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4982) Glyco_hydro2_C5 PF18565.1 OAG05253.1 - 4e-15 55.5 0.0 9.5e-15 54.3 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_N PF02837.18 OAG05253.1 - 9e-14 51.7 2.4 2.2e-13 50.4 2.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Invasin_D3 PF09134.10 OAG05253.1 - 0.00022 21.5 0.0 0.00022 21.5 0.0 3.0 3 1 1 4 4 4 1 Invasin, domain 3 F5_F8_type_C PF00754.25 OAG05253.1 - 0.00023 21.3 1.0 0.00023 21.3 1.0 2.7 3 0 0 3 3 3 1 F5/8 type C domain Trypsin PF00089.26 OAG05254.1 - 2e-12 47.4 0.5 2.6e-12 47.0 0.5 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OAG05254.1 - 0.00019 22.4 0.1 0.00041 21.3 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain SGL PF08450.12 OAG05255.1 - 1.1e-06 28.4 1.4 0.00035 20.3 0.7 2.3 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF2141 PF09912.9 OAG05255.1 - 0.0022 17.9 0.0 0.054 13.4 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2141) NHL PF01436.21 OAG05255.1 - 0.029 14.4 1.3 16 5.8 0.0 3.6 4 0 0 4 4 4 0 NHL repeat Macoilin PF09726.9 OAG05256.1 - 7.6 4.9 9.1 9.7 4.6 9.1 1.1 1 0 0 1 1 1 0 Macoilin family NAD_binding_4 PF07993.12 OAG05257.1 - 4.6e-30 104.6 0.0 7.9e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG05257.1 - 7.9e-29 100.5 0.0 1.2e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAG05257.1 - 1.4e-07 31.2 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG05257.1 - 8.9e-07 29.2 0.0 2.7e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF308 PF03729.13 OAG05258.1 - 0.13 12.6 13.9 0.48 10.8 0.7 3.6 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF2474 PF10617.9 OAG05258.1 - 8.5 6.3 10.7 6.8 6.6 2.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2474) ketoacyl-synt PF00109.26 OAG05259.1 - 4.9e-70 236.0 0.0 1.3e-69 234.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG05259.1 - 1.1e-54 186.1 0.4 2.3e-54 185.0 0.4 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG05259.1 - 4.2e-53 180.5 0.0 8.6e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAG05259.1 - 9.6e-48 162.5 0.0 3.3e-47 160.7 0.0 2.0 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 OAG05259.1 - 1.6e-37 128.1 0.0 4.3e-37 126.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAG05259.1 - 1.4e-19 70.6 0.0 6.4e-19 68.5 0.0 2.3 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 OAG05259.1 - 6.9e-17 62.0 0.0 2.4e-16 60.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05259.1 - 1.1e-11 45.3 0.0 5.5e-11 43.0 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG05259.1 - 2.3e-10 40.5 0.1 8.3e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG05259.1 - 4.7e-07 29.7 0.0 1.7e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG05259.1 - 4.9e-07 30.3 0.0 3.1e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 OAG05259.1 - 7.2e-07 29.5 0.0 3.1e-06 27.4 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OAG05259.1 - 1.5e-05 24.5 0.0 4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 OAG05259.1 - 2.2e-05 23.9 0.0 4.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 OAG05259.1 - 0.00012 21.7 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF938 PF06080.12 OAG05259.1 - 0.0015 18.3 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Thiolase_N PF00108.23 OAG05259.1 - 0.028 13.8 0.3 0.064 12.6 0.3 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 OAG05259.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase DUF3632 PF12311.8 OAG05260.1 - 3e-38 132.0 0.1 4e-38 131.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) p450 PF00067.22 OAG05261.1 - 5.9e-65 219.8 0.0 7.9e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL_2 PF13472.6 OAG05262.1 - 7.3e-21 75.4 0.1 1.1e-20 74.8 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG05262.1 - 8.5e-11 42.2 0.0 1.1e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FliN_N PF16973.5 OAG05262.1 - 0.043 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal SnoaL_4 PF13577.6 OAG05264.1 - 1.4e-07 31.7 0.0 1.8e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG05264.1 - 0.0001 22.9 0.0 0.00012 22.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 OAG05264.1 - 0.023 15.3 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain HLH PF00010.26 OAG05266.1 - 3.5e-14 52.5 0.1 1.4e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Bromodomain PF00439.25 OAG05267.1 - 1e-08 35.1 0.0 6.5e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 Bromodomain SlyX PF04102.12 OAG05268.1 - 0.0038 17.8 0.8 0.007 17.0 0.8 1.5 1 0 0 1 1 1 1 SlyX AAA_lid_9 PF17871.1 OAG05268.1 - 0.0046 16.8 0.1 0.0081 16.1 0.1 1.3 1 0 0 1 1 1 1 AAA lid domain RIC3 PF15361.6 OAG05268.1 - 0.036 14.5 1.0 0.082 13.3 1.0 1.6 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Sugarporin_N PF11471.8 OAG05268.1 - 0.04 13.9 4.2 0.071 13.1 4.2 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Csm1_N PF18504.1 OAG05268.1 - 0.061 13.7 1.6 0.1 12.9 1.6 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain adh_short PF00106.25 OAG05269.1 - 1.1e-22 80.5 0.0 1.7e-21 76.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05269.1 - 1.4e-16 60.8 0.0 6e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG05269.1 - 0.00013 21.6 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PGA_cap PF09587.10 OAG05269.1 - 0.037 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap SnoaL_2 PF12680.7 OAG05271.1 - 0.01 16.5 0.1 0.014 16.1 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain zf-C2HC5 PF06221.13 OAG05272.1 - 3.7e-23 81.3 7.1 6e-23 80.6 7.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Pro_isomerase PF00160.21 OAG05273.1 - 3.4e-53 180.1 0.0 3.9e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADH_N PF08240.12 OAG05274.1 - 1.9e-27 95.3 0.1 3.3e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG05274.1 - 4.6e-07 29.9 0.2 9e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG05274.1 - 5.6e-06 26.2 0.1 5.6e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 OAG05274.1 - 0.0018 17.8 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG05274.1 - 0.0028 17.0 0.2 0.0049 16.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG05274.1 - 0.045 12.5 0.1 0.059 12.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Costars PF14705.6 OAG05274.1 - 0.087 13.0 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Costars HET PF06985.11 OAG05275.1 - 0.018 15.4 0.0 0.38 11.1 0.0 2.1 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Arginase PF00491.21 OAG05277.1 - 7.9e-23 81.3 0.0 1.1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family CHAT PF12770.7 OAG05278.1 - 3.7e-41 141.4 0.0 5.8e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 CHAT domain adh_short PF00106.25 OAG05280.1 - 2.3e-27 95.7 5.6 8.5e-14 51.5 0.1 3.1 2 1 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05280.1 - 4e-23 82.2 1.5 2e-13 50.5 0.0 2.9 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG05280.1 - 4.1e-06 26.8 0.1 8.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_23 PF13489.6 OAG05281.1 - 4.5e-13 49.4 0.0 6.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG05281.1 - 5.6e-07 30.1 0.0 2.9e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG05281.1 - 2.3e-06 27.5 0.0 6.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG05281.1 - 1.4e-05 25.8 0.0 6.2e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05281.1 - 0.00065 20.4 0.0 0.017 15.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OAG05282.1 - 1e-38 132.8 0.0 1.4e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05282.1 - 6.9e-24 84.7 0.0 8.5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SbcD_C PF12320.8 OAG05282.1 - 0.004 17.4 0.0 0.0069 16.7 0.0 1.3 1 0 0 1 1 1 1 Type 5 capsule protein repressor C-terminal domain DUF1776 PF08643.10 OAG05282.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 OAG05282.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 OAG05282.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding NACHT PF05729.12 OAG05283.1 - 1.5e-09 38.0 0.0 3.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG05283.1 - 1e-05 26.0 0.1 7.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 OAG05283.1 - 0.00015 21.8 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea MbeD_MobD PF04899.12 OAG05283.1 - 0.0015 18.6 0.1 0.0037 17.3 0.1 1.6 1 0 0 1 1 1 1 MbeD/MobD like AAA_29 PF13555.6 OAG05283.1 - 0.0038 16.9 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 OAG05283.1 - 0.005 16.1 0.0 0.0099 15.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 OAG05283.1 - 0.0071 16.9 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OAG05283.1 - 0.013 15.8 0.0 0.051 13.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG05283.1 - 0.013 16.1 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG05283.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG05283.1 - 0.042 14.3 0.0 0.095 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SesA PF17107.5 OAG05283.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_23 PF13476.6 OAG05283.1 - 0.17 12.4 0.0 0.68 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG05283.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain HET PF06985.11 OAG05285.1 - 8.3e-24 84.6 0.0 2.6e-23 83.0 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LPMO_10 PF03067.15 OAG05287.1 - 6.1e-08 33.5 0.3 8e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF4448 PF14610.6 OAG05288.1 - 9.3e-07 28.8 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ZU5 PF00791.20 OAG05288.1 - 0.15 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 ZU5 domain NinB PF05772.12 OAG05289.1 - 0.23 11.3 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 NinB protein L51_S25_CI-B8 PF05047.16 OAG05290.1 - 1.9e-15 56.5 0.1 3.2e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GET2 PF08690.10 OAG05291.1 - 6.2e-31 108.2 0.6 6.3e-29 101.6 0.6 2.0 1 1 0 1 1 1 1 GET complex subunit GET2 LAM_C PF12544.8 OAG05292.1 - 2.9e-05 24.2 0.1 6.5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 OAG05292.1 - 0.00052 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 OAG05292.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.6 OAG05292.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain IBR PF01485.21 OAG05293.1 - 9.1e-09 35.4 20.5 2.9e-06 27.4 8.7 2.5 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain DUF2299 PF10061.9 OAG05293.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) zf-RING_2 PF13639.6 OAG05293.1 - 6.9 7.1 34.6 0.1 13.0 5.9 3.3 3 0 0 3 3 3 0 Ring finger domain Glyco_hydro_127 PF07944.12 OAG05294.1 - 4.4e-136 454.4 2.1 5.1e-136 454.2 2.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Stress-antifung PF01657.17 OAG05294.1 - 0.035 14.7 0.1 0.087 13.5 0.1 1.6 1 0 0 1 1 1 0 Salt stress response/antifungal Glyco_hydro_92 PF07971.12 OAG05295.1 - 5.7e-138 460.7 0.9 6.9e-138 460.4 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG05295.1 - 1.3e-48 166.0 2.5 1.9e-48 165.5 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain p450 PF00067.22 OAG05296.1 - 2.5e-42 145.2 0.0 3.2e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PAF-AH_p_II PF03403.13 OAG05297.1 - 6.3e-19 67.7 0.0 2.1e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG05297.1 - 1e-05 24.6 0.0 1.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 OAG05297.1 - 0.00046 20.9 0.1 0.00071 20.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG05297.1 - 0.0042 16.7 0.2 0.072 12.7 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 OAG05297.1 - 0.037 13.8 0.2 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 OAG05297.1 - 0.041 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 OAG05297.1 - 0.13 11.5 0.1 0.64 9.2 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Fungal_trans_2 PF11951.8 OAG05298.1 - 4.9e-12 45.3 1.1 3e-11 42.7 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG05298.1 - 0.00077 19.5 10.2 0.0012 18.9 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 OAG05299.1 - 1.5e-12 47.5 0.5 8.1e-05 22.0 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 OAG05299.1 - 0.032 13.5 0.0 0.4 9.9 0.0 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PQQ_2 PF13360.6 OAG05301.1 - 0.00039 20.1 0.3 0.13 11.8 0.0 3.5 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 OAG05301.1 - 0.038 13.9 0.7 1.2 9.2 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 OAG05301.1 - 2.5 8.7 14.0 3.4 8.3 0.1 5.0 5 0 0 5 5 5 0 PQQ-like domain Lipase_GDSL_2 PF13472.6 OAG05302.1 - 0.001 19.5 0.1 0.048 14.1 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family HMG_box PF00505.19 OAG05303.1 - 5.4e-23 81.2 0.3 9.3e-23 80.4 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG05303.1 - 6.5e-07 29.9 0.1 1.3e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain MAJIN PF15077.6 OAG05303.1 - 0.15 11.8 0.7 0.3 10.8 0.7 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Abhydrolase_3 PF07859.13 OAG05304.1 - 1.2e-36 126.5 0.0 1.7e-25 90.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold NCE101 PF11654.8 OAG05304.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Non-classical export protein 1 DUF2207 PF09972.9 OAG05305.1 - 0.052 12.3 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 OAG05305.1 - 0.074 12.5 1.1 0.17 11.3 1.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAG05305.1 - 0.097 12.6 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 TMEM154 protein family CFEM PF05730.11 OAG05305.1 - 2.3 8.4 6.4 4.3 7.5 6.4 1.4 1 0 0 1 1 1 0 CFEM domain Aminotran_1_2 PF00155.21 OAG05306.1 - 2.3e-68 231.0 0.0 2.6e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG05306.1 - 2.9e-05 23.6 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 OAG05306.1 - 4.2e-05 23.0 0.0 6.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OAG05306.1 - 0.00012 20.8 0.1 0.0003 19.4 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG05306.1 - 0.0029 16.6 0.1 0.0067 15.4 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-V MgsA_C PF12002.8 OAG05307.1 - 4.7e-59 199.1 0.1 8.7e-59 198.2 0.1 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 OAG05307.1 - 2.6e-21 75.7 0.1 8.3e-21 74.1 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 OAG05307.1 - 1.9e-13 51.0 0.2 6.7e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG05307.1 - 2.3e-08 33.9 0.0 4.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 OAG05307.1 - 8.1e-06 25.6 0.1 0.034 13.8 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 OAG05307.1 - 7.9e-05 22.7 0.0 0.00024 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG05307.1 - 0.00019 21.9 0.7 0.021 15.2 0.2 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 OAG05307.1 - 0.00025 20.3 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAG05307.1 - 0.00071 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAG05307.1 - 0.00078 18.9 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 OAG05307.1 - 0.0011 19.3 0.2 0.0055 17.0 0.2 2.3 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.11 OAG05307.1 - 0.0052 16.6 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OAG05307.1 - 0.011 16.2 0.0 0.024 15.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAG05307.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAG05307.1 - 0.015 15.3 0.6 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.22 OAG05307.1 - 0.015 15.4 0.2 0.037 14.1 0.1 1.7 2 0 0 2 2 1 0 Shikimate kinase DNA_pol3_delta2 PF13177.6 OAG05307.1 - 0.023 14.5 0.0 0.39 10.5 0.0 2.4 2 1 0 2 2 1 0 DNA polymerase III, delta subunit TsaE PF02367.17 OAG05307.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 OAG05307.1 - 0.046 13.8 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OAG05307.1 - 0.051 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 OAG05307.1 - 0.055 12.9 0.1 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 Bacterial TniB protein AAA_18 PF13238.6 OAG05307.1 - 0.057 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG05307.1 - 0.079 12.9 0.2 7.5 6.4 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 OAG05307.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 OAG05307.1 - 0.093 11.9 0.3 0.41 9.8 0.1 1.9 1 1 1 2 2 2 0 NB-ARC domain AAA_13 PF13166.6 OAG05307.1 - 0.13 10.9 0.7 0.18 10.4 0.1 1.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG05307.1 - 0.16 11.7 0.3 1.7 8.3 0.2 2.1 1 1 0 2 2 2 0 AAA domain Pro-kuma_activ PF09286.11 OAG05308.1 - 2.6e-35 121.8 0.0 3.6e-34 118.1 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG05308.1 - 5.8e-08 32.3 0.0 9.8e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Subtilase family WSC PF01822.19 OAG05309.1 - 2e-14 53.5 6.5 4.2e-14 52.5 6.5 1.5 1 0 0 1 1 1 1 WSC domain Pectate_lyase_3 PF12708.7 OAG05310.1 - 2.9e-08 33.8 4.6 2.9e-08 33.8 4.6 3.2 2 1 1 3 3 3 1 Pectate lyase superfamily protein Glyco_hydro_28 PF00295.17 OAG05310.1 - 2e-07 30.4 5.6 1.5e-06 27.5 5.6 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 MFS_1 PF07690.16 OAG05311.1 - 8e-26 90.8 42.2 8e-26 90.8 42.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAG05312.1 - 1.8e-05 24.8 13.7 3.4e-05 23.9 13.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG05312.1 - 0.0068 15.5 0.2 0.013 14.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.20 OAG05313.1 - 1.4e-40 140.0 0.0 2e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase EGF_2 PF07974.13 OAG05314.1 - 1.7e-05 25.0 8.9 3.7e-05 24.0 8.9 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 OAG05314.1 - 0.0022 18.2 7.4 0.0045 17.3 7.4 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 OAG05314.1 - 0.0083 16.7 4.3 0.018 15.6 4.3 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF CBM64 PF18666.1 OAG05314.1 - 0.031 14.3 0.6 0.11 12.5 0.2 2.2 2 1 0 2 2 2 0 Carbohydrate-binding module 64 EB PF01683.18 OAG05314.1 - 0.032 14.5 1.3 0.056 13.7 1.3 1.3 1 0 0 1 1 1 0 EB module Squash PF00299.18 OAG05314.1 - 0.25 11.4 2.4 0.48 10.5 2.4 1.4 1 0 0 1 1 1 0 Squash family serine protease inhibitor Laminin_EGF PF00053.24 OAG05314.1 - 1.3 9.2 7.0 2.6 8.3 7.0 1.4 1 0 0 1 1 1 0 Laminin EGF domain SNF2_N PF00176.23 OAG05317.1 - 1.7e-40 138.8 0.0 1.7e-37 129.0 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG05317.1 - 1.6e-06 28.4 0.0 3.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Na_H_Exchanger PF00999.21 OAG05318.1 - 1.5e-58 198.4 43.2 2.2e-58 197.9 43.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3343 PF11823.8 OAG05321.1 - 0.19 11.2 0.1 0.42 10.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3343) p450 PF00067.22 OAG05322.1 - 3.2e-55 187.7 0.0 4e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.11 OAG05323.1 - 0.00063 19.8 6.5 0.0011 19.0 6.5 1.4 1 0 0 1 1 1 1 CFEM domain LrgB PF04172.16 OAG05323.1 - 5.8 6.4 9.6 0.62 9.5 4.3 2.1 2 1 0 2 2 2 0 LrgB-like family MFS_1 PF07690.16 OAG05324.1 - 1.3e-25 90.1 33.1 4.5e-14 52.2 11.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 OAG05324.1 - 1.4e-12 47.4 1.7 1.7e-12 47.1 1.7 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.7 OAG05324.1 - 9.1e-11 41.2 3.3 1.2e-10 40.8 3.3 1.2 1 0 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 OAG05324.1 - 0.0052 15.7 3.0 0.0052 15.7 3.0 1.6 1 1 1 2 2 2 2 Sugar (and other) transporter DUF4396 PF14342.6 OAG05324.1 - 0.024 15.0 3.3 0.1 12.9 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Transglut_core PF01841.19 OAG05324.1 - 0.036 14.5 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily WD40 PF00400.32 OAG05325.1 - 4e-20 71.8 14.9 6.3e-05 23.7 0.0 10.1 11 0 0 11 11 11 4 WD domain, G-beta repeat PD40 PF07676.12 OAG05325.1 - 0.012 15.5 0.0 1.1 9.3 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 OAG05325.1 - 0.039 13.5 2.0 0.72 9.4 0.1 3.3 3 1 0 3 3 3 0 PQQ-like domain AMP-binding PF00501.28 OAG05327.1 - 3.8e-87 292.6 0.1 4.9e-87 292.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG05327.1 - 6.6e-28 97.5 0.1 3.2e-26 92.1 0.2 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAG05327.1 - 1.5e-19 69.7 0.8 3.5e-19 68.5 0.8 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Reprolysin_5 PF13688.6 OAG05328.1 - 2.3e-60 204.1 8.4 2.3e-60 204.1 8.4 2.7 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAG05328.1 - 6.6e-47 159.9 4.8 6.6e-47 159.9 4.8 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAG05328.1 - 1.6e-44 152.0 4.1 2.9e-44 151.2 4.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OAG05328.1 - 3e-15 56.8 34.4 3e-15 56.8 34.4 4.5 3 2 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 OAG05328.1 - 1.6e-12 48.0 0.1 4.7e-12 46.5 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 OAG05328.1 - 4e-05 24.0 15.2 4e-05 24.0 15.2 4.7 1 1 3 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 OAG05328.1 - 0.013 15.8 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Reprolysin family propeptide PUMA PF15826.5 OAG05329.1 - 0.01 16.0 3.3 0.012 15.8 3.3 1.1 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis FKBP_N PF01346.18 OAG05329.1 - 0.069 14.1 0.3 0.096 13.7 0.3 1.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Nop14 PF04147.12 OAG05330.1 - 0.028 12.7 13.7 0.036 12.3 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 OAG05330.1 - 0.061 12.1 12.9 0.086 11.6 12.9 1.3 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OAG05330.1 - 0.081 11.2 13.4 0.11 10.7 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 OAG05330.1 - 0.11 11.3 11.1 0.16 10.8 11.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 OAG05330.1 - 0.11 10.9 7.8 0.15 10.4 7.8 1.1 1 0 0 1 1 1 0 Menin AAA_11 PF13086.6 OAG05330.1 - 0.19 11.5 9.8 0.32 10.8 9.8 1.3 1 0 0 1 1 1 0 AAA domain Paramyxo_ncap PF00973.19 OAG05330.1 - 0.39 9.6 5.2 0.54 9.1 5.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Neur_chan_memb PF02932.16 OAG05330.1 - 0.42 10.6 5.6 0.77 9.8 5.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 OAG05330.1 - 0.84 8.4 14.2 1.5 7.5 14.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SPATA3 PF15662.5 OAG05330.1 - 1.2 9.7 12.7 16 6.0 8.8 2.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family FAM60A PF15396.6 OAG05330.1 - 1.2 9.1 9.9 2.8 7.9 9.9 1.6 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 OAG05330.1 - 1.2 8.0 10.8 2.1 7.3 10.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 OAG05330.1 - 1.8 8.3 10.8 3.9 7.2 10.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 OAG05330.1 - 2.1 7.5 11.5 3.3 6.8 11.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 OAG05330.1 - 3.7 6.8 11.1 6.1 6.1 11.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S64 PF08192.11 OAG05330.1 - 6.1 5.2 15.0 8.7 4.7 15.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 CorA PF01544.18 OAG05331.1 - 0.0033 16.8 1.8 0.0033 16.8 1.8 1.8 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein AAA PF00004.29 OAG05332.1 - 3.1e-39 134.4 0.1 4.2e-38 130.8 0.0 2.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG05332.1 - 7.3e-09 35.3 0.2 2.1e-08 33.9 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OAG05332.1 - 5.1e-05 23.1 0.0 0.00039 20.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAG05332.1 - 0.0027 17.9 0.1 0.012 15.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG05332.1 - 0.0036 17.3 0.0 0.01 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG05332.1 - 0.0055 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OAG05332.1 - 0.008 16.5 2.1 0.081 13.2 0.1 3.3 4 0 0 4 4 4 1 AAA domain TIP49 PF06068.13 OAG05332.1 - 0.011 14.9 0.4 0.022 14.0 0.1 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_14 PF13173.6 OAG05332.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG05332.1 - 0.014 15.9 0.0 0.038 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG05332.1 - 0.023 15.1 0.1 0.023 15.1 0.1 4.2 3 1 1 5 5 5 0 AAA ATPase domain AAA_28 PF13521.6 OAG05332.1 - 0.024 14.9 0.0 0.077 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG05332.1 - 0.031 14.0 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OAG05332.1 - 0.048 14.1 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.21 OAG05332.1 - 0.08 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 OAG05332.1 - 0.099 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cutinase PF01083.22 OAG05334.1 - 1.9e-55 187.5 10.7 2.2e-55 187.4 10.7 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG05334.1 - 4.4e-06 26.4 0.2 6.3e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 OAG05334.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.7 OAG05334.1 - 0.032 14.9 0.1 0.034 14.7 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG05334.1 - 0.037 13.7 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_2 PF01674.18 OAG05334.1 - 0.29 10.6 5.5 1.5 8.3 5.5 1.9 1 1 0 1 1 1 0 Lipase (class 2) DUF1768 PF08719.11 OAG05335.1 - 1.6e-29 103.2 0.1 2.3e-29 102.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Lyase_1 PF00206.20 OAG05336.1 - 3.1e-48 164.8 0.0 5.4e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAG05336.1 - 2.3e-18 66.5 0.0 9e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HET PF06985.11 OAG05338.1 - 3.9e-28 98.7 0.2 5.6e-28 98.1 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX PF00293.28 OAG05339.1 - 4.6e-11 42.9 0.0 7.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PTH2 PF01981.16 OAG05340.1 - 7.6e-45 152.0 0.1 1e-44 151.6 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PhzC-PhzF PF02567.16 OAG05340.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein SART-1 PF03343.13 OAG05341.1 - 9.7e-176 586.0 69.9 1.1e-175 585.8 69.9 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydr_30_2 PF14587.6 OAG05342.1 - 9.5e-17 61.6 6.4 3.4e-16 59.8 0.2 2.4 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 OAG05342.1 - 9.3e-16 57.9 6.7 1.9e-15 56.9 6.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 OAG05342.1 - 2.2e-12 47.0 4.4 1.2e-11 44.6 4.1 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 OAG05342.1 - 5.3e-09 35.5 0.2 9.1e-09 34.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain S-methyl_trans PF02574.16 OAG05342.1 - 0.039 13.8 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase adh_short PF00106.25 OAG05343.1 - 1.1e-30 106.6 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05343.1 - 1.9e-27 96.3 0.0 2.3e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG05343.1 - 1.3e-05 25.2 0.1 0.0001 22.3 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG05343.1 - 0.0054 16.2 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG05343.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Tyrosinase PF00264.20 OAG05344.1 - 1.6e-49 169.2 1.4 2.3e-49 168.7 1.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1100 PF06500.11 OAG05344.1 - 0.053 12.3 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF2079 PF09852.9 OAG05345.1 - 0.024 13.5 0.1 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) DUF3487 PF11990.8 OAG05345.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) HET PF06985.11 OAG05346.1 - 3.2e-27 95.7 0.0 6e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_L28 PF00830.19 OAG05347.1 - 6.4e-16 58.3 0.7 1.3e-15 57.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Drf_GBD PF06371.13 OAG05348.1 - 0.054 13.1 2.5 0.066 12.8 1.5 1.6 1 1 1 2 2 2 0 Diaphanous GTPase-binding Domain Aldo_ket_red PF00248.21 OAG05349.1 - 2.4e-05 23.7 0.1 0.0016 17.7 0.0 2.7 2 1 0 2 2 2 1 Aldo/keto reductase family ADH_zinc_N PF00107.26 OAG05350.1 - 1.1e-09 38.3 0.0 1.7e-05 24.8 0.1 2.2 1 1 1 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG05350.1 - 0.00018 20.9 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SKG6 PF08693.10 OAG05351.1 - 0.049 13.1 0.3 0.049 13.1 0.3 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sugar_tr PF00083.24 OAG05352.1 - 3.1e-76 257.1 19.5 3.6e-76 256.8 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG05352.1 - 5.9e-30 104.4 23.3 3e-18 65.9 10.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG05352.1 - 7.9e-06 24.6 2.1 7.9e-06 24.6 2.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7TM-7TMR_HD PF07698.11 OAG05352.1 - 0.018 14.8 1.4 0.018 14.8 1.4 2.6 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Pox_A14 PF05767.12 OAG05352.1 - 4.8 7.4 6.1 1.3 9.3 0.2 2.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 GST_N_3 PF13417.6 OAG05353.1 - 2.3e-16 59.9 0.0 5.9e-16 58.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG05353.1 - 6.2e-13 48.9 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG05353.1 - 1.5e-10 41.2 0.0 4.3e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG05353.1 - 2.6e-09 37.2 0.1 5.8e-09 36.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG05353.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCCH PF00642.24 OAG05355.1 - 0.00027 20.8 3.7 0.00054 19.8 3.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OAG05355.1 - 0.00077 20.1 0.1 0.0018 18.9 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 OAG05355.1 - 0.0044 17.0 10.0 0.0044 17.0 10.0 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 OAG05355.1 - 0.022 14.6 6.9 0.038 13.8 6.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 OAG05355.1 - 0.03 14.5 1.3 0.071 13.3 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger containing family Hemerythrin PF01814.23 OAG05357.1 - 2.9e-10 40.9 0.1 4.2e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain p450 PF00067.22 OAG05358.1 - 1e-29 103.7 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HHH_4 PF14490.6 OAG05358.1 - 0.0046 16.9 0.0 0.02 14.8 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix containing domain Proton_antipo_M PF00361.20 OAG05358.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Proton-conducting membrane transporter DUF829 PF05705.14 OAG05359.1 - 5.6e-38 131.2 0.0 6.6e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF1082 PF06449.11 OAG05360.1 - 0.043 13.7 0.2 0.094 12.6 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) p450 PF00067.22 OAG05361.1 - 2.6e-44 151.7 0.0 3.8e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_2 PF07719.17 OAG05363.1 - 1.1e-07 31.4 5.9 0.0014 18.6 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG05363.1 - 3.7e-05 24.3 2.1 0.00097 19.7 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG05363.1 - 4.2e-05 23.7 0.4 0.16 12.3 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG05363.1 - 5.9e-05 23.0 0.1 0.042 14.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG05363.1 - 0.0001 21.9 0.4 0.16 11.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG05363.1 - 0.00045 20.7 1.2 0.0068 16.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG05363.1 - 0.0035 18.0 3.3 0.27 12.2 0.0 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG05363.1 - 0.006 16.4 0.8 14 5.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG05363.1 - 0.033 14.8 1.3 0.25 12.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG05363.1 - 0.042 13.2 0.5 0.091 12.1 0.5 1.7 1 1 0 1 1 1 0 MalT-like TPR region TPR_11 PF13414.6 OAG05363.1 - 0.093 12.4 1.7 10 5.9 0.0 3.5 3 1 1 4 4 4 0 TPR repeat Yip1 PF04893.17 OAG05364.1 - 0.0019 17.9 0.7 0.0023 17.7 0.7 1.1 1 0 0 1 1 1 1 Yip1 domain DUF2892 PF11127.8 OAG05364.1 - 0.056 13.5 3.7 0.13 12.3 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) DUF202 PF02656.15 OAG05364.1 - 0.09 13.2 2.0 0.17 12.4 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 OAG05364.1 - 1.6 8.4 6.7 2 8.1 6.7 1.1 1 0 0 1 1 1 0 Tetraspanin family Radical_SAM_C PF16199.5 OAG05365.1 - 1.6e-32 111.3 0.2 4.9e-32 109.8 0.0 1.9 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OAG05365.1 - 1e-18 68.3 0.1 4.2e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OAG05365.1 - 1.1e-09 38.6 0.1 2.5e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG05365.1 - 2e-06 27.8 0.1 1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG05365.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 OAG05366.1 - 5.9e-27 94.2 3.5 8.7e-27 93.7 0.6 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OAG05366.1 - 9.3e-25 87.2 0.3 1.6e-24 86.5 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAG05366.1 - 2e-09 37.4 0.1 3.6e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OAG05366.1 - 2e-05 25.0 0.0 5.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain DUF2431 PF10354.9 OAG05367.1 - 9.3e-58 195.2 0.0 1.2e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CLTH PF10607.9 OAG05368.1 - 1.7e-30 105.9 0.0 2.9e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PLU-1 PF08429.11 OAG05368.1 - 0.0031 16.7 0.8 0.0052 16.0 0.8 1.3 1 0 0 1 1 1 1 PLU-1-like protein LisH PF08513.11 OAG05368.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 LisH zf-Di19 PF05605.12 OAG05368.1 - 0.13 12.6 2.4 0.33 11.3 2.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ABC_tran PF00005.27 OAG05369.1 - 1.8e-47 161.3 0.0 1.6e-22 80.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAG05369.1 - 8.8e-22 76.9 1.7 8.8e-22 76.9 1.7 2.9 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 OAG05369.1 - 2.2e-20 73.7 0.6 0.00022 21.1 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG05369.1 - 5.9e-11 42.2 0.6 0.19 11.2 0.0 4.4 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG05369.1 - 2.9e-09 37.7 9.1 0.00072 20.1 0.0 3.9 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.6 OAG05369.1 - 4.5e-09 35.9 0.1 0.0017 18.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OAG05369.1 - 8.1e-08 32.4 0.3 0.0089 15.8 0.0 3.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_16 PF13191.6 OAG05369.1 - 1e-06 29.2 0.0 0.0047 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG05369.1 - 1.1e-06 28.7 0.2 0.0055 16.6 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 OAG05369.1 - 5.1e-05 23.6 0.1 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG05369.1 - 6.7e-05 23.4 0.0 0.15 12.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 OAG05369.1 - 0.00016 21.7 0.0 0.19 11.9 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG05369.1 - 0.00025 21.3 0.0 0.45 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 OAG05369.1 - 0.00041 20.0 0.0 0.26 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG05369.1 - 0.00043 20.2 0.4 0.6 10.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 OAG05369.1 - 0.00067 20.1 0.1 1.6 9.1 0.2 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OAG05369.1 - 0.00073 19.3 0.3 1 9.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAG05369.1 - 0.00091 19.6 5.0 1.4 9.4 0.0 3.7 4 0 0 4 4 3 1 RNA helicase Roc PF08477.13 OAG05369.1 - 0.0018 18.4 0.0 2.7 8.2 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 OAG05369.1 - 0.0021 17.3 1.0 5.3 6.1 0.0 3.8 4 0 0 4 4 4 0 NB-ARC domain AAA_5 PF07728.14 OAG05369.1 - 0.0022 18.0 0.1 1.7 8.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAG05369.1 - 0.0078 16.4 0.2 2.4 8.3 0.1 2.9 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 OAG05369.1 - 0.012 15.7 1.3 11 6.1 0.0 3.8 3 1 1 4 4 4 0 Dynamin family AAA_30 PF13604.6 OAG05369.1 - 0.015 15.0 0.2 1.5 8.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 OAG05369.1 - 0.02 14.4 0.5 2 7.9 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_14 PF13173.6 OAG05369.1 - 0.022 14.8 0.1 9.4 6.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain Ras PF00071.22 OAG05369.1 - 0.029 14.0 0.0 8.4 6.0 0.1 2.6 2 0 0 2 2 2 0 Ras family DUF815 PF05673.13 OAG05369.1 - 0.031 13.4 0.1 5.2 6.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 OAG05369.1 - 0.034 13.9 1.0 2.3 8.0 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 OAG05369.1 - 0.037 12.8 0.2 11 4.7 0.0 3.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAG05369.1 - 0.038 13.6 0.2 1.4 8.5 0.0 3.1 4 0 0 4 4 4 0 AAA domain MCM PF00493.23 OAG05369.1 - 0.041 13.0 0.0 4.2 6.4 0.0 2.5 2 0 0 2 2 2 0 MCM P-loop domain DUF2813 PF11398.8 OAG05369.1 - 0.059 12.6 4.4 6 6.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2813) Phage_tail_2 PF06199.11 OAG05369.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Phage tail tube protein ATPase_2 PF01637.18 OAG05369.1 - 0.088 12.7 0.1 16 5.3 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 OAG05369.1 - 0.096 12.6 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 OAG05369.1 - 0.098 12.9 0.4 8.4 6.7 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit HPP PF04982.13 OAG05370.1 - 6.3e-38 129.7 2.4 6.3e-38 129.7 2.4 2.1 1 1 1 2 2 2 1 HPP family DUF973 PF06157.11 OAG05370.1 - 0.17 10.9 1.6 0.27 10.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) SNF2_N PF00176.23 OAG05371.1 - 2.6e-53 181.0 0.2 8.9e-52 175.9 0.2 2.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG05371.1 - 5.9e-16 58.8 0.0 4.4e-15 56.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 OAG05371.1 - 4.2e-05 23.3 10.1 4.2e-05 23.3 10.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 OAG05371.1 - 9e-05 21.5 0.0 0.0002 20.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 OAG05371.1 - 0.0046 16.8 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAG05371.1 - 0.031 13.5 0.1 0.082 12.1 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DRAT PF07357.11 OAG05371.1 - 0.031 13.5 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Zn_Tnp_IS91 PF14319.6 OAG05371.1 - 2.2 8.3 14.0 6.8 6.8 1.5 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-C3HC4_3 PF13920.6 OAG05371.1 - 3.9 7.4 20.7 0.029 14.2 9.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG05371.1 - 4.3 7.4 22.9 0.025 14.5 10.8 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Pho88 PF10032.9 OAG05372.1 - 9.8e-82 272.6 0.0 1.1e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 OAG05372.1 - 0.018 15.8 0.2 1.4 9.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) 2-Hacid_dh_C PF02826.19 OAG05373.1 - 1.8e-45 154.4 0.0 3.1e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG05373.1 - 0.00045 19.9 0.0 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 OAG05373.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 OAG05373.1 - 0.038 14.1 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 OAG05373.1 - 0.066 13.7 0.0 0.15 12.5 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 OAG05373.1 - 0.2 12.1 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_11 PF08241.12 OAG05374.1 - 1.3e-15 57.8 0.0 2.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05374.1 - 1.2e-14 54.7 0.0 2.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG05374.1 - 2.8e-11 43.5 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG05374.1 - 4.4e-11 42.9 0.0 5.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG05374.1 - 3.1e-10 40.7 0.0 5.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG05374.1 - 1.6e-06 27.7 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OAG05374.1 - 0.00053 19.4 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG05374.1 - 0.0012 18.4 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 OAG05374.1 - 0.0023 16.9 0.0 0.0032 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 OAG05374.1 - 0.0035 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OAG05374.1 - 0.055 13.5 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 OAG05374.1 - 0.063 13.0 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Fungal_TACC PF12709.7 OAG05375.1 - 0.01 16.2 1.0 0.012 16.0 1.0 1.1 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins BTB PF00651.31 OAG05376.1 - 3.7e-06 27.1 0.0 7.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TraV PF09676.10 OAG05376.1 - 4.4 8.3 11.0 0.44 11.5 5.3 2.1 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Glyco_hydro_26 PF02156.15 OAG05377.1 - 3.2e-79 266.6 8.3 4.3e-79 266.2 8.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 OAG05377.1 - 7e-30 103.8 4.7 1.5e-29 102.8 4.7 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) DUF5010_C PF18099.1 OAG05377.1 - 0.01 16.0 0.1 0.024 14.8 0.1 1.6 1 0 0 1 1 1 0 DUF5010 C-terminal domain DUF4185 PF13810.6 OAG05378.1 - 0.046 13.0 0.1 8.9 5.4 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4185) Lactamase_B PF00753.27 OAG05379.1 - 5.2e-12 46.2 1.6 8.2e-12 45.5 1.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG05379.1 - 3.5e-07 29.9 0.3 5.6e-07 29.3 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NDUF_B12 PF08122.12 OAG05381.1 - 8.2e-23 80.2 1.8 1.4e-22 79.5 1.8 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 OAG05382.1 - 1.7e-23 83.3 0.0 4e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 CAF1 family ribonuclease Methyltransf_23 PF13489.6 OAG05383.1 - 8.9e-15 54.9 0.0 2.8e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05383.1 - 2.4e-08 34.6 0.0 7.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG05383.1 - 3.2e-07 30.3 0.0 5.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG05383.1 - 1.4e-05 25.7 0.0 0.00072 20.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG05383.1 - 4.7e-05 24.0 0.0 0.17 12.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 OAG05383.1 - 0.00014 21.4 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 OAG05383.1 - 0.00024 20.7 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OAG05383.1 - 0.0054 16.9 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase HGTP_anticodon PF03129.20 OAG05384.1 - 6.4e-21 74.3 0.0 3.1e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAG05384.1 - 5.8e-08 32.9 0.1 2.7e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Brix PF04427.18 OAG05385.1 - 3.5e-17 63.1 0.0 5.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Brix domain DUF5525 PF17663.1 OAG05385.1 - 0.027 12.6 0.1 0.035 12.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) RIO1 PF01163.22 OAG05385.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.4 3 0 0 3 3 3 0 RIO1 family RRN3 PF05327.11 OAG05385.1 - 0.41 9.1 3.4 0.58 8.6 3.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 OAG05385.1 - 0.98 8.7 24.6 1.4 8.1 24.6 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 OAG05385.1 - 1 7.4 7.5 1.5 6.8 7.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 OAG05385.1 - 5.2 5.2 23.3 6.7 4.8 23.3 1.1 1 0 0 1 1 1 0 Nop14-like family PBD PF00786.28 OAG05387.1 - 0.0061 16.9 0.1 0.088 13.2 0.0 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain 4HBT_3 PF13622.6 OAG05390.1 - 1.6e-19 71.2 1.8 2.2e-19 70.7 1.8 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily CH PF00307.31 OAG05391.1 - 1.1e-47 160.7 0.2 3e-23 82.1 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 OAG05391.1 - 5.4e-29 100.1 1.5 9.4e-26 89.7 0.1 3.0 2 0 0 2 2 2 2 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 OAG05391.1 - 3.5e-11 42.8 0.2 6.2e-07 29.2 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 OAG05391.1 - 0.00013 21.6 0.9 0.0022 17.8 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain Spectrin PF00435.21 OAG05391.1 - 0.00091 19.7 5.7 0.76 10.3 0.1 3.1 2 0 0 2 2 2 2 Spectrin repeat EF-hand_1 PF00036.32 OAG05391.1 - 0.0078 15.7 0.1 0.19 11.3 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OAG05391.1 - 0.0081 16.6 3.2 0.067 13.7 0.9 3.1 2 0 0 2 2 2 1 EF-hand domain pair NADH-UOR_E PF16514.5 OAG05391.1 - 0.018 15.4 0.3 0.62 10.4 0.0 3.1 2 0 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E EF-hand_8 PF13833.6 OAG05391.1 - 0.028 14.3 0.4 0.2 11.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Anillin_N PF16018.5 OAG05391.1 - 0.12 13.0 0.3 0.33 11.6 0.3 1.7 1 0 0 1 1 1 0 Anillin N-terminus FTO_CTD PF12934.7 OAG05391.1 - 0.34 10.7 3.7 0.27 11.0 0.6 2.4 2 1 1 3 3 3 0 FTO C-terminal domain FliG_N PF14842.6 OAG05391.1 - 1 9.9 5.4 1.5 9.4 0.2 3.3 3 1 0 4 4 4 0 FliG N-terminal domain DUF2884 PF11101.8 OAG05391.1 - 1.7 8.1 9.3 0.38 10.2 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) Sipho_Gp157 PF05565.11 OAG05391.1 - 2.7 8.0 10.7 0.26 11.3 1.7 2.7 3 0 0 3 3 3 0 Siphovirus Gp157 DUF4508 PF14969.6 OAG05391.1 - 3.2 8.1 8.1 2 8.7 0.9 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4508) Na_H_Exchanger PF00999.21 OAG05392.1 - 8.5e-31 107.1 31.1 1.7e-26 92.9 19.8 2.8 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family Pkinase PF00069.25 OAG05393.1 - 1e-66 225.0 0.5 1e-65 221.8 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG05393.1 - 4.3e-52 177.0 0.0 8.9e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OAG05393.1 - 1e-21 77.0 0.0 3.1e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 OAG05393.1 - 9.1e-07 28.0 0.5 2.3e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 OAG05393.1 - 2.6e-06 27.9 0.4 5.4e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OAG05393.1 - 1.9e-05 24.2 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAG05393.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OAG05393.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OAG05393.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family MFS_1 PF07690.16 OAG05394.1 - 6e-27 94.5 21.3 7.7e-27 94.1 21.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DIOX_N PF14226.6 OAG05395.1 - 1.2e-19 71.2 0.1 9e-19 68.4 0.0 2.2 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG05395.1 - 4.4e-15 56.0 0.0 7.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tup_N PF08581.10 OAG05395.1 - 0.035 14.4 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Tup N-terminal adh_short PF00106.25 OAG05396.1 - 2.2e-19 69.7 3.3 2.3e-11 43.5 0.3 3.5 3 1 1 4 4 4 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05396.1 - 2e-10 40.7 0.9 1.6e-06 27.9 0.3 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase PIG-P PF08510.12 OAG05397.1 - 4.7e-47 158.9 2.1 1.1e-46 157.7 2.1 1.6 1 0 0 1 1 1 1 PIG-P His_Phos_2 PF00328.22 OAG05397.1 - 1.1e-13 51.3 0.9 8e-12 45.2 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DPM2 PF07297.12 OAG05397.1 - 0.13 12.6 7.5 0.31 11.4 7.5 1.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Glyco_hydro_3_C PF01915.22 OAG05398.1 - 1.4e-44 152.5 0.0 2.5e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OAG05398.1 - 9.5e-27 92.9 0.4 1.9e-26 91.9 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 OAG05398.1 - 1.1e-17 64.4 0.0 2.1e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Aminotran_1_2 PF00155.21 OAG05400.1 - 4.8e-83 279.3 0.0 6.2e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG05400.1 - 7.6e-06 24.7 0.0 1.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG05400.1 - 0.00077 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG05400.1 - 0.02 14.2 0.2 0.036 13.4 0.2 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.8 OAG05400.1 - 0.032 12.9 0.2 0.048 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) FlgN PF05130.12 OAG05401.1 - 0.046 14.2 0.6 0.11 13.1 0.1 1.9 2 0 0 2 2 2 0 FlgN protein HTH_ABP1_N PF18107.1 OAG05401.1 - 0.061 13.0 0.6 0.65 9.8 0.0 2.5 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain GSH_synth_ATP PF03917.17 OAG05402.1 - 8.3e-142 472.4 0.0 9.5e-142 472.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OAG05402.1 - 3.1e-35 120.7 0.0 5.9e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Cupin_6 PF12852.7 OAG05403.1 - 0.063 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF4203 PF13886.6 OAG05404.1 - 1.6e-50 171.6 28.3 2.2e-50 171.1 28.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2681 PF10883.8 OAG05404.1 - 1.7 9.1 8.6 1.5 9.3 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Erf4 PF10256.9 OAG05405.1 - 9.2e-41 138.6 0.0 1.2e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Sec1 PF00995.23 OAG05406.1 - 2.5e-131 439.7 0.0 2.9e-131 439.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family NAD_binding_10 PF13460.6 OAG05407.1 - 3.6e-09 36.8 0.2 5.9e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG05407.1 - 4.1e-08 33.0 0.1 4.6e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG05407.1 - 4.6e-06 26.4 0.1 1.1e-05 25.1 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.24 OAG05407.1 - 1.4e-05 25.5 0.0 0.00031 21.2 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG05407.1 - 0.00023 20.3 0.0 0.008 15.2 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.22 OAG05407.1 - 0.0026 18.6 0.1 0.011 16.6 0.1 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GDP_Man_Dehyd PF16363.5 OAG05407.1 - 0.0099 15.3 0.2 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG05407.1 - 0.06 12.5 0.0 0.2 10.8 0.0 1.9 2 1 0 2 2 2 0 Male sterility protein Zn_clus PF00172.18 OAG05408.1 - 5.4e-09 36.0 7.8 1e-08 35.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG05408.1 - 4.4e-08 32.5 0.3 7.1e-08 31.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep3 PF16846.5 OAG05408.1 - 0.0021 16.6 0.0 0.0031 16.1 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B TMEM174 PF15029.6 OAG05408.1 - 0.027 14.2 0.3 0.043 13.5 0.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 BAR PF03114.18 OAG05409.1 - 9e-49 166.3 6.8 1.1e-48 165.9 6.8 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 OAG05409.1 - 1.2e-05 24.6 4.1 1.6e-05 24.2 4.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3086 PF11285.8 OAG05409.1 - 0.016 14.4 2.2 0.026 13.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Arfaptin PF06456.13 OAG05409.1 - 0.051 13.1 9.2 0.099 12.2 8.6 1.8 2 1 0 2 2 2 0 Arfaptin-like domain OmpH PF03938.14 OAG05409.1 - 0.55 10.6 13.0 0.32 11.3 10.2 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GBP_C PF02841.14 OAG05409.1 - 0.8 9.0 15.3 0.035 13.5 9.6 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain TMPIT PF07851.13 OAG05409.1 - 5 6.3 6.9 2.2 7.5 4.6 1.5 2 0 0 2 2 2 0 TMPIT-like protein Glyco_hydro_11 PF00457.17 OAG05410.1 - 8.8e-56 188.3 13.3 1.1e-55 188.1 13.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Abhydrolase_1 PF00561.20 OAG05412.1 - 7.8e-26 91.3 0.0 1.6e-25 90.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG05412.1 - 5.6e-15 56.5 0.0 8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG05412.1 - 3.2e-10 39.7 0.0 4.8e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAG05412.1 - 5.7e-05 22.9 0.0 0.016 14.9 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OAG05412.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain LCAT PF02450.15 OAG05412.1 - 0.006 15.8 0.0 0.0091 15.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Esterase PF00756.20 OAG05412.1 - 0.0097 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 OAG05412.1 - 0.017 13.9 0.0 0.039 12.6 0.0 1.7 1 1 0 1 1 1 0 Ndr family Palm_thioest PF02089.15 OAG05412.1 - 0.021 14.6 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 OAG05412.1 - 0.025 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG05412.1 - 0.032 13.2 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF915 PF06028.11 OAG05412.1 - 0.061 12.7 0.1 0.25 10.7 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 OAG05412.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Ank_2 PF12796.7 OAG05413.1 - 3.6e-35 120.4 0.0 3.8e-10 40.2 0.0 4.4 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG05413.1 - 2.9e-24 84.8 0.1 3.1e-07 30.5 0.3 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG05413.1 - 1.3e-19 68.2 0.3 0.0032 17.8 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 OAG05413.1 - 8.1e-18 64.6 0.1 0.073 13.7 0.1 6.7 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG05413.1 - 4.5e-13 49.0 0.6 0.013 15.9 0.0 6.5 6 1 0 6 6 6 3 Ankyrin repeat Peptidase_S10 PF00450.22 OAG05414.1 - 2.9e-87 293.8 1.5 8.6e-87 292.2 1.5 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase ketoacyl-synt PF00109.26 OAG05415.1 - 1.6e-74 250.7 0.0 1.3e-73 247.8 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OAG05415.1 - 6.8e-58 195.5 0.0 2e-57 194.0 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 OAG05415.1 - 8.1e-49 166.8 1.8 9.9e-27 94.3 0.3 2.4 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG05415.1 - 3.8e-36 123.7 0.6 4e-35 120.4 0.6 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAG05415.1 - 4.5e-12 46.2 0.0 1.4e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 OAG05415.1 - 2.8e-09 37.4 0.0 7e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OAG05415.1 - 4.8e-07 29.4 0.0 1.7e-05 24.4 0.0 3.1 2 1 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.6 OAG05415.1 - 6e-06 25.7 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Polyketide synthase dehydratase Thiolase_N PF00108.23 OAG05415.1 - 1.2e-05 24.8 0.6 7.2e-05 22.3 0.2 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain Dsh_C PF12316.8 OAG05417.1 - 0.67 10.3 10.3 1.1 9.6 10.3 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DAO PF01266.24 OAG05419.1 - 2.4e-42 145.8 0.6 2.7e-42 145.6 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG05419.1 - 1.3e-05 24.4 0.0 0.073 12.1 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG05419.1 - 3.6e-05 23.2 0.1 0.17 11.1 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG05419.1 - 0.00026 20.2 1.6 0.34 10.0 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Mqo PF06039.15 OAG05419.1 - 0.00053 18.7 0.2 0.001 17.7 0.0 1.5 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 OAG05419.1 - 0.001 17.8 0.1 0.0051 15.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein GMC_oxred_N PF00732.19 OAG05419.1 - 0.0018 17.7 0.0 0.67 9.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG05419.1 - 0.0024 18.1 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG05419.1 - 0.003 17.6 0.2 2 8.4 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAG05419.1 - 0.015 14.2 1.3 1.4 7.7 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase GARS_N PF02844.15 OAG05419.1 - 0.069 13.9 0.0 0.17 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain FAD_binding_2 PF00890.24 OAG05419.1 - 0.13 11.3 2.1 1.2 8.1 2.1 2.1 1 1 0 1 1 1 0 FAD binding domain Ribosomal_L28e PF01778.17 OAG05420.1 - 4.6e-29 101.5 0.1 6.3e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.10 OAG05421.1 - 2.7e-46 156.0 0.0 3.1e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) MFS_1 PF07690.16 OAG05422.1 - 1.5e-21 76.7 16.8 1.5e-21 76.7 16.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Patatin PF01734.22 OAG05423.1 - 4.7e-08 33.5 0.1 1.5e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase DUF4325 PF14213.6 OAG05423.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Zn_clus PF00172.18 OAG05424.1 - 2.1e-09 37.4 9.5 3.4e-09 36.7 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG05424.1 - 0.00022 20.1 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EPL1 PF10513.9 OAG05425.1 - 3.7e-26 92.4 1.7 7.7e-26 91.3 0.1 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like SET PF00856.28 OAG05426.1 - 3.5e-24 86.1 0.1 3.3e-23 82.9 0.0 2.1 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 OAG05426.1 - 1.2e-08 35.7 1.0 3.6e-08 34.2 0.3 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Peptidase_M22 PF00814.25 OAG05427.1 - 1.7e-84 283.7 0.0 2e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OAG05427.1 - 0.16 11.6 0.0 0.54 9.9 0.0 1.8 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus HET PF06985.11 OAG05428.1 - 1e-30 107.0 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 OAG05428.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) F-box-like_2 PF13013.6 OAG05428.1 - 0.11 12.5 0.7 0.19 11.7 0.3 1.7 1 1 1 2 2 2 0 F-box-like domain UL11 PF11094.8 OAG05428.1 - 0.44 10.5 1.9 4 7.4 0.1 2.9 4 0 0 4 4 4 0 Membrane-associated tegument protein Gly_transf_sug PF04488.15 OAG05429.1 - 5.1e-21 75.1 0.0 1.2e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAG05429.1 - 0.046 13.0 1.5 0.86 8.8 0.2 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Metallothio PF00131.20 OAG05430.1 - 0.0081 16.3 4.8 0.017 15.2 4.8 1.5 1 0 0 1 1 1 1 Metallothionein TMEM132D_C PF15706.5 OAG05431.1 - 0.042 13.6 0.4 0.042 13.6 0.4 2.0 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Flavi_NS4A PF01350.17 OAG05431.1 - 0.05 13.5 0.5 0.096 12.6 0.5 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A DUF3169 PF11368.8 OAG05431.1 - 0.74 9.3 5.4 0.16 11.5 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) AMPKBI PF04739.15 OAG05433.1 - 8.4e-25 86.8 1.2 3.1e-24 85.0 1.2 2.1 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 OAG05433.1 - 2.9e-24 85.1 0.0 4.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Sugar_tr PF00083.24 OAG05434.1 - 1.5e-80 271.3 18.6 1.7e-80 271.1 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG05434.1 - 1.6e-18 66.8 23.2 1.6e-18 66.8 23.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 OAG05434.1 - 6.8 4.8 7.9 0.22 9.8 1.7 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) CMAS PF02353.20 OAG05436.1 - 6.3e-38 130.6 0.3 8.7e-38 130.2 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 OAG05436.1 - 5.2e-18 65.3 0.0 6.9e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05436.1 - 9.6e-18 64.7 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG05436.1 - 8.1e-17 61.7 0.0 1.4e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG05436.1 - 7.4e-13 48.7 0.0 1.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG05436.1 - 1.7e-11 44.7 0.0 2.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG05436.1 - 2.2e-07 30.6 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAG05436.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 OAG05436.1 - 5.2e-05 22.7 0.0 0.00051 19.5 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 OAG05436.1 - 0.00018 21.0 0.0 0.00096 18.7 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 OAG05436.1 - 0.0015 18.3 0.0 0.004 16.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF938) PCMT PF01135.19 OAG05436.1 - 0.0021 17.9 0.0 0.014 15.2 0.0 2.2 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAG05436.1 - 0.0049 17.0 0.0 0.13 12.4 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 OAG05436.1 - 0.005 16.2 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 OAG05436.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 OAG05436.1 - 0.051 13.1 0.1 0.081 12.4 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 OAG05436.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GidB PF02527.15 OAG05436.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_7 PF03492.15 OAG05436.1 - 0.15 11.2 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase Rep_fac_C PF08542.11 OAG05438.1 - 4.4e-17 62.3 0.2 1.6e-16 60.5 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAG05438.1 - 9.4e-17 61.7 0.0 1.7e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAG05438.1 - 3.2e-12 46.5 0.0 1.3e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 OAG05438.1 - 4e-09 36.7 0.0 6.9e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 OAG05438.1 - 7.4e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 OAG05438.1 - 1.4e-06 28.6 0.0 4.8e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 OAG05438.1 - 1.7e-06 28.5 0.0 8.6e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 OAG05438.1 - 2.6e-06 27.4 0.2 0.00013 21.9 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG05438.1 - 3.2e-06 27.2 0.2 1.7e-05 24.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OAG05438.1 - 3.7e-06 26.8 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 OAG05438.1 - 3.7e-06 26.8 0.2 7e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 OAG05438.1 - 8e-06 26.2 0.1 4.8e-05 23.7 0.0 2.3 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 OAG05438.1 - 2.2e-05 23.8 0.0 4.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAG05438.1 - 8.3e-05 22.4 0.0 0.00037 20.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAG05438.1 - 0.00032 20.1 0.1 0.011 15.1 0.1 2.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAG05438.1 - 0.00034 20.5 0.1 0.0014 18.5 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAG05438.1 - 0.00064 20.1 0.1 0.0022 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAG05438.1 - 0.00087 19.3 0.0 0.0024 17.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 OAG05438.1 - 0.0012 18.4 0.0 0.32 10.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 OAG05438.1 - 0.0014 18.7 0.0 0.088 12.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 OAG05438.1 - 0.0036 17.0 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF2075 PF09848.9 OAG05438.1 - 0.0082 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 OAG05438.1 - 0.0084 15.9 0.1 0.055 13.2 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase NACHT PF05729.12 OAG05438.1 - 0.016 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 OAG05438.1 - 0.018 15.3 0.0 0.035 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAG05438.1 - 0.018 14.4 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 OAG05438.1 - 0.022 15.3 0.0 0.04 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG05438.1 - 0.026 14.1 0.1 0.063 12.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG05438.1 - 0.028 14.4 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 OAG05438.1 - 0.03 13.5 0.0 0.091 11.9 0.0 1.7 1 1 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 OAG05438.1 - 0.037 13.6 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG05438.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 OAG05438.1 - 0.083 12.6 0.0 0.78 9.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 OAG05438.1 - 0.098 11.8 0.2 0.31 10.2 0.0 1.9 3 0 0 3 3 3 0 TIP49 P-loop domain TK PF00265.18 OAG05438.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Thymidine kinase P21-Arc PF04062.14 OAG05439.1 - 8.1e-73 244.1 0.0 9.4e-73 243.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 OAG05440.1 - 3.7e-116 387.5 0.0 3.1e-115 384.4 0.0 1.9 2 0 0 2 2 2 1 Gcd10p family DUF1726 PF08351.11 OAG05440.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) MINDY_DUB PF04424.13 OAG05441.1 - 1.8e-25 89.2 0.0 3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase ORC6 PF05460.13 OAG05442.1 - 0.051 12.8 1.2 0.064 12.5 1.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3860 PF12976.7 OAG05442.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) CNDH2_M PF16869.5 OAG05442.1 - 0.15 12.8 6.0 0.13 13.0 4.8 1.5 1 1 0 1 1 1 0 PF16858 Oxidored_FMN PF00724.20 OAG05443.1 - 4.6e-74 249.7 0.0 6.8e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 OAG05443.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Transp_cyt_pur PF02133.15 OAG05444.1 - 2.2e-18 66.3 42.5 5e-18 65.1 42.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2208 PF09973.9 OAG05444.1 - 3.8 7.0 11.4 4.9 6.7 3.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Transp_cyt_pur PF02133.15 OAG05445.1 - 3e-84 283.3 30.9 3.5e-84 283.1 30.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 OAG05446.1 - 3.4e-32 111.5 0.7 5.1e-32 111.0 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG05446.1 - 9.7e-08 32.0 8.2 9.7e-08 32.0 8.2 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K_oxygenase PF13434.6 OAG05446.1 - 0.097 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) PSI_integrin PF17205.3 OAG05446.1 - 1 9.2 7.9 0.4 10.4 2.1 2.7 2 0 0 2 2 2 0 Integrin plexin domain Polysacc_deac_1 PF01522.21 OAG05447.1 - 1e-12 48.0 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase MFS_1 PF07690.16 OAG05448.1 - 4.2e-51 173.9 42.5 2.3e-50 171.5 43.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG05448.1 - 8.5e-17 61.1 3.9 8.5e-17 61.1 3.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAG05448.1 - 3.7e-15 55.4 19.7 1e-14 53.9 19.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Amidase PF01425.21 OAG05449.1 - 2.7e-64 217.8 0.0 3e-63 214.3 0.0 2.2 1 1 0 1 1 1 1 Amidase DUF3526 PF12040.8 OAG05449.1 - 0.06 13.8 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) HATPase_c PF02518.26 OAG05450.1 - 3.9e-27 95.0 0.0 9.3e-27 93.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG05450.1 - 4.9e-23 81.4 0.5 9.3e-23 80.5 0.5 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG05450.1 - 2.9e-16 59.3 0.5 9.2e-16 57.6 0.5 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 OAG05450.1 - 5.5e-15 55.5 0.0 7e-13 48.7 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAG05450.1 - 4.3e-14 52.5 0.0 3.9e-09 36.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 OAG05450.1 - 4.9e-14 52.5 0.0 1.9e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 OAG05450.1 - 3.1e-06 27.4 0.0 3.3e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 PAS fold Ytp1 PF10355.9 OAG05451.1 - 5.3e-69 232.5 20.0 5.3e-69 232.5 20.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAG05451.1 - 3.1e-32 110.5 0.2 3.1e-32 110.5 0.2 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Acetyltransf_3 PF13302.7 OAG05451.1 - 0.15 12.7 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Swi5 PF07061.11 OAG05452.1 - 1.4e-23 82.8 0.2 3.6e-23 81.4 0.2 1.8 1 0 0 1 1 1 1 Swi5 p450 PF00067.22 OAG05453.1 - 6e-53 180.2 0.0 1.1e-52 179.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_Prp PF04327.12 OAG05454.1 - 0.011 16.0 0.3 0.016 15.5 0.3 1.3 1 0 0 1 1 1 0 Cysteine protease Prp HAP1_N PF04849.13 OAG05454.1 - 0.031 13.5 0.6 0.046 12.9 0.6 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region SPATA1_C PF15743.5 OAG05454.1 - 0.04 14.0 1.1 0.06 13.4 1.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus TSC22 PF01166.18 OAG05454.1 - 0.14 12.5 0.5 0.31 11.4 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Pkinase PF00069.25 OAG05456.1 - 1.2e-65 221.5 0.0 1.4e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG05456.1 - 5.9e-29 101.1 0.0 7.9e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG05456.1 - 0.004 16.5 0.0 0.014 14.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG05456.1 - 0.0055 15.5 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OAG05456.1 - 0.0092 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG05456.1 - 0.012 15.0 0.2 0.02 14.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAG05456.1 - 0.032 13.8 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family AA_kinase PF00696.28 OAG05457.1 - 2.5e-43 148.4 0.1 3.9e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 OAG05457.1 - 1.8e-09 37.3 1.1 2.9e-07 30.2 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 OAG05457.1 - 8.1e-09 35.1 0.6 4.7e-06 26.3 0.1 3.6 2 1 1 3 3 3 2 ACT domain adh_short PF00106.25 OAG05458.1 - 8.1e-24 84.2 0.1 1.5e-22 80.0 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05458.1 - 9.6e-13 48.2 0.1 1.1e-11 44.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG05458.1 - 1.8e-06 28.0 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG05458.1 - 0.041 13.0 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Putative_PNPOx PF01243.20 OAG05459.1 - 6.7e-19 67.9 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 OAG05459.1 - 1.3e-13 50.7 2.3 2.2e-13 50.0 2.3 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 OAG05459.1 - 7.8e-06 26.4 0.0 1.3e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 OAG05459.1 - 0.063 12.9 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like Myb_DNA-binding PF00249.31 OAG05460.1 - 7.9e-12 45.2 0.2 7.3e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG05460.1 - 3.4e-06 27.2 1.6 0.095 13.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG05460.1 - 0.0042 17.0 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Myb DNA-binding like DUF4230 PF14014.6 OAG05460.1 - 1.1 9.5 6.4 2.2 8.5 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DS PF01916.17 OAG05461.1 - 1.2e-131 438.2 0.0 1.4e-131 438.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase MORN PF02493.20 OAG05462.1 - 8.6e-15 53.7 27.0 8.4e-07 28.5 1.3 5.0 5 0 0 5 5 5 4 MORN repeat zf-C3HC4_3 PF13920.6 OAG05462.1 - 2.6e-11 43.2 7.8 4.7e-11 42.4 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.8 OAG05462.1 - 4.9e-08 32.6 0.0 1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Prok-RING_4 PF14447.6 OAG05462.1 - 6.5e-05 22.7 6.6 0.00013 21.7 6.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UCH PF00443.29 OAG05462.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.6 OAG05462.1 - 0.008 16.5 7.8 0.008 16.5 7.8 2.1 2 0 0 2 2 2 1 Ring finger domain MATH PF00917.26 OAG05462.1 - 0.091 12.9 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 MATH domain Porin_5 PF16930.5 OAG05462.1 - 0.097 11.1 0.7 0.15 10.5 0.7 1.2 1 0 0 1 1 1 0 Putative porin zf-C3HC4 PF00097.25 OAG05462.1 - 0.11 12.4 11.4 0.84 9.6 7.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG05462.1 - 0.25 11.4 11.1 0.14 12.2 7.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG05462.1 - 0.45 10.4 11.0 1.8 8.5 7.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pep3_Vps18 PF05131.14 OAG05463.1 - 6.5e-47 159.1 0.7 2.9e-46 157.0 0.0 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OAG05463.1 - 6e-11 42.4 12.7 1.6e-09 37.8 1.4 3.5 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 OAG05463.1 - 9.4e-05 22.8 0.0 0.0003 21.2 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 OAG05463.1 - 0.00087 18.9 0.3 0.0021 17.6 0.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 OAG05463.1 - 0.0024 17.7 1.1 0.0059 16.4 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG05463.1 - 0.0029 17.5 0.3 0.0066 16.4 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG05463.1 - 0.011 16.1 0.9 0.03 14.7 0.9 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 OAG05463.1 - 0.011 15.4 4.0 0.031 14.0 4.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger DUF2175 PF09943.9 OAG05463.1 - 0.036 14.4 0.1 0.036 14.4 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_UBOX PF13445.6 OAG05463.1 - 0.06 13.4 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zf_RING PF16744.5 OAG05463.1 - 0.076 13.1 0.8 5.9 7.1 0.1 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger DUF1664 PF07889.12 OAG05463.1 - 0.13 12.3 2.6 1.3 9.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-rbx1 PF12678.7 OAG05463.1 - 0.13 12.5 0.4 0.34 11.2 0.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG05463.1 - 0.16 11.9 0.6 0.4 10.6 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Herpes_U44 PF04533.13 OAG05463.1 - 0.17 11.5 1.3 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 Herpes virus U44 protein zf-C3H2C3 PF17122.5 OAG05463.1 - 3.5 7.7 8.7 0.12 12.4 2.5 1.8 2 0 0 2 2 1 0 Zinc-finger Terminase_3C PF17288.2 OAG05466.1 - 0.0034 17.8 0.1 0.0085 16.5 0.1 1.7 1 0 0 1 1 1 1 Terminase RNAseH like domain PT PF04886.12 OAG05466.1 - 0.016 14.7 1.5 0.039 13.5 1.5 1.7 1 0 0 1 1 1 0 PT repeat NOA36 PF06524.12 OAG05466.1 - 5.3 6.3 14.8 12 5.1 14.8 1.5 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAG05466.1 - 6.4 4.9 14.4 11 4.1 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein HET PF06985.11 OAG05469.1 - 2.7e-25 89.4 1.4 1.3e-24 87.2 0.0 2.6 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) S_4TM PF18159.1 OAG05470.1 - 0.049 12.9 1.0 0.053 12.8 1.0 1.0 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain T5orf172 PF10544.9 OAG05472.1 - 1.7e-25 89.5 0.8 8.4e-25 87.3 0.8 2.2 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAG05472.1 - 1.7e-23 83.1 0.1 4e-23 81.9 0.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 zf-primase PF09329.11 OAG05472.1 - 0.021 14.6 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Primase zinc finger NACHT PF05729.12 OAG05473.1 - 9.9e-05 22.3 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Amidase PF01425.21 OAG05475.1 - 6.1e-107 358.4 0.0 1.1e-106 357.5 0.0 1.4 1 1 0 1 1 1 1 Amidase DEAD PF00270.29 OAG05476.1 - 5.2e-39 133.8 0.0 9.1e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG05476.1 - 3.5e-24 85.3 0.0 3.4e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG05476.1 - 5.7e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAG05476.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Forkhead PF00250.18 OAG05479.1 - 1.3e-35 121.5 0.3 2.3e-35 120.7 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain IGPD PF00475.18 OAG05480.1 - 2.7e-59 199.6 0.1 9.5e-59 197.8 0.3 1.7 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 OAG05480.1 - 0.18 9.0 0.0 0.23 8.6 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase RNA_pol_L_2 PF13656.6 OAG05481.1 - 2e-31 107.6 0.0 2.5e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAG05481.1 - 1.9e-12 46.5 0.0 2.7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 OAG05482.1 - 4.8e-07 30.4 2.3 9.3e-07 29.5 2.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAG05482.1 - 2.9e-05 24.0 0.3 5.2e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) IKKbetaNEMObind PF12179.8 OAG05482.1 - 0.069 13.2 0.1 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain G10 PF01125.17 OAG05483.1 - 4.9e-66 221.0 6.1 5.4e-66 220.9 6.1 1.0 1 0 0 1 1 1 1 G10 protein SKG6 PF08693.10 OAG05484.1 - 0.14 11.6 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Macoilin PF09726.9 OAG05484.1 - 2.2 6.7 6.2 4.2 5.8 6.2 1.4 1 0 0 1 1 1 0 Macoilin family ArgJ PF01960.18 OAG05486.1 - 1.5e-151 504.5 2.9 1.7e-151 504.3 2.9 1.0 1 0 0 1 1 1 1 ArgJ family NmrA PF05368.13 OAG05487.1 - 4.7e-37 127.8 0.0 5.8e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG05487.1 - 1.4e-14 54.4 0.0 1.9e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG05487.1 - 2.8e-06 27.0 0.0 1.1e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG05487.1 - 4.7e-05 22.7 0.0 0.0011 18.2 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 OAG05487.1 - 0.0032 16.5 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG05487.1 - 0.0069 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG05487.1 - 0.013 14.7 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 OAG05487.1 - 0.032 14.3 0.0 0.064 13.4 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 OAG05487.1 - 0.053 13.4 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF2804 PF10974.8 OAG05489.1 - 0.0082 15.7 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) Integrin_B_tail PF07965.12 OAG05490.1 - 3.9 8.0 7.2 20 5.8 0.1 3.4 3 0 0 3 3 3 0 Integrin beta tail domain Glyco_hydro_31 PF01055.26 OAG05491.1 - 1.4e-91 307.9 4.8 3.2e-91 306.7 4.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 OAG05491.1 - 3.5e-05 24.0 0.0 9.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) DUF5110 PF17137.4 OAG05491.1 - 9e-05 22.7 0.2 0.014 15.7 0.2 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5110) Lipase_GDSL_2 PF13472.6 OAG05492.1 - 1.8e-14 54.6 0.2 4.3e-14 53.3 0.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG05492.1 - 2.1e-09 37.6 0.0 5.8e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase UreF PF01730.16 OAG05493.1 - 1.4e-23 83.9 0.8 2.3e-23 83.2 0.8 1.3 1 0 0 1 1 1 1 UreF Pox_A_type_inc PF04508.12 OAG05493.1 - 0.0067 16.2 1.7 0.028 14.3 0.4 2.3 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat Sugarporin_N PF11471.8 OAG05493.1 - 0.042 13.8 0.3 0.042 13.8 0.3 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Spo12 PF05032.12 OAG05494.1 - 7.3e-14 51.4 4.2 7.3e-14 51.4 4.2 2.7 3 1 1 4 4 4 1 Spo12 family Unstab_antitox PF09720.10 OAG05494.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative addiction module component PLDc_2 PF13091.6 OAG05495.1 - 3.5e-19 69.0 0.2 8.2e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.8 OAG05495.1 - 0.032 13.4 0.0 2.2 7.4 0.0 2.5 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB PLDc PF00614.22 OAG05495.1 - 0.049 13.8 0.2 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase D Active site motif Cyclase PF04199.13 OAG05497.1 - 7e-15 55.5 0.0 9.6e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Acetyltransf_3 PF13302.7 OAG05498.1 - 0.007 17.0 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG05498.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG05498.1 - 0.043 13.8 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein UAF_Rrn10 PF05234.11 OAG05498.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 UAF complex subunit Rrn10 DUF89 PF01937.19 OAG05500.1 - 2.6e-134 447.7 0.0 3e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF2423 PF10338.9 OAG05502.1 - 9.4e-20 70.6 1.8 9.4e-20 70.6 1.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) BNIP3 PF06553.12 OAG05502.1 - 0.36 10.5 3.6 0.45 10.2 1.2 1.9 2 0 0 2 2 2 0 BNIP3 PINIT PF14324.6 OAG05503.1 - 4.5e-38 130.9 0.3 8.4e-38 130.0 0.3 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 OAG05503.1 - 1.9e-18 65.9 2.9 3.1e-18 65.2 2.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OAG05503.1 - 2.1e-07 30.6 1.1 4.5e-07 29.6 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 OAG05503.1 - 7.7e-06 25.5 1.7 1.4e-05 24.7 0.2 2.1 2 0 0 2 2 2 1 SAP domain Prok-RING_4 PF14447.6 OAG05503.1 - 0.054 13.4 1.6 0.1 12.5 1.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Sec23_Sec24 PF04810.15 OAG05503.1 - 0.12 12.4 2.0 0.26 11.4 2.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Glycos_transf_1 PF00534.20 OAG05504.1 - 1.3e-20 73.6 0.0 3.2e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG05504.1 - 2.2e-15 57.3 0.0 4.6e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OAG05504.1 - 0.00078 19.8 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 WD40 PF00400.32 OAG05505.1 - 8.2e-59 194.2 12.7 1.1e-08 35.6 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 OAG05505.1 - 2.1e-18 66.4 6.5 4.2e-18 65.4 6.5 1.5 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 OAG05505.1 - 5.3e-17 61.9 0.0 0.00038 20.7 0.0 5.7 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG05505.1 - 7.6e-10 38.6 0.0 0.0048 16.3 0.0 5.3 4 1 2 6 6 6 2 WD40-like domain Nup160 PF11715.8 OAG05505.1 - 1.4e-05 24.0 0.5 0.13 10.9 0.0 3.7 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAG05505.1 - 0.00017 20.5 0.1 0.019 13.8 0.1 3.2 2 1 1 3 3 3 2 Nup133 N terminal like Ge1_WD40 PF16529.5 OAG05505.1 - 0.00047 19.2 0.2 4.5 6.1 0.0 4.3 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 OAG05505.1 - 0.0026 16.2 0.0 0.65 8.2 0.0 3.3 4 0 0 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 OAG05505.1 - 0.008 14.7 0.3 0.1 11.1 0.2 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain Golgin_A5 PF09787.9 OAG05505.1 - 0.038 13.5 1.7 0.054 13.0 1.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 MMS1_N PF10433.9 OAG05505.1 - 0.092 11.4 0.0 5.2 5.6 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.6 OAG05505.1 - 0.1 11.9 0.1 4.6 6.5 0.0 2.6 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal THP2 PF09432.10 OAG05505.1 - 0.18 11.9 0.4 0.29 11.2 0.4 1.3 1 0 0 1 1 1 0 Tho complex subunit THP2 SHE3 PF17078.5 OAG05505.1 - 0.36 10.5 3.4 4.3 7.0 1.2 2.1 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 zf-C2H2 PF00096.26 OAG05508.1 - 6.4e-20 70.4 23.3 6.8e-05 23.1 1.0 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG05508.1 - 7.9e-17 60.8 21.4 1.6e-08 34.6 0.4 5.1 6 0 0 6 6 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG05508.1 - 3.1e-09 36.9 21.6 0.031 15.1 0.7 5.3 5 0 0 5 5 4 4 C2H2-type zinc finger zf-met PF12874.7 OAG05508.1 - 0.0031 17.8 8.8 0.93 10.0 0.0 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 OAG05508.1 - 0.028 14.6 3.1 0.28 11.3 0.3 2.8 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 OAG05508.1 - 0.077 13.0 16.7 0.089 12.8 1.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger C1_4 PF07975.12 OAG05508.1 - 0.083 13.1 1.7 0.2 11.9 0.5 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain BolA PF01722.18 OAG05508.1 - 0.099 12.9 0.2 0.47 10.8 0.2 2.2 1 1 0 1 1 1 0 BolA-like protein zf-LYAR PF08790.11 OAG05508.1 - 0.19 11.7 10.8 35 4.4 0.0 4.6 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 OAG05508.1 - 0.3 10.7 8.8 8 6.2 0.0 4.5 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 OAG05508.1 - 0.44 10.4 3.0 0.55 10.1 0.5 2.6 2 1 1 3 3 3 0 GAGA factor FOXP-CC PF16159.5 OAG05508.1 - 0.82 10.4 3.3 25 5.6 0.3 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 OAG05508.1 - 1.6 9.0 9.0 17 5.6 5.4 3.4 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2HE PF16278.5 OAG05508.1 - 1.9 9.0 12.7 0.47 10.9 1.4 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger C1_1 PF00130.22 OAG05508.1 - 3.3 7.7 6.0 2.4 8.1 0.3 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 OAG05508.1 - 4.5 7.5 7.6 23 5.2 7.6 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-AN1 PF01428.16 OAG05508.1 - 5 7.4 10.2 15 5.9 1.6 3.6 3 1 0 3 3 3 0 AN1-like Zinc finger Cu_amine_oxid PF01179.20 OAG05511.1 - 5.8e-125 417.4 8.9 8.1e-125 416.9 8.9 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 OAG05511.1 - 6.5e-28 96.3 0.4 1.5e-27 95.2 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 OAG05511.1 - 3.3e-05 24.0 0.0 7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain FA_hydroxylase PF04116.13 OAG05512.1 - 6e-24 84.9 20.1 7.6e-24 84.6 16.1 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily BRE1 PF08647.11 OAG05512.1 - 0.21 11.7 0.4 0.3 11.2 0.4 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase MBOAT_2 PF13813.6 OAG05513.1 - 7.7e-16 58.1 3.9 2.1e-15 56.8 1.6 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MMR_HSR1_Xtn PF16897.5 OAG05514.1 - 1.2e-34 118.5 0.3 3.8e-34 116.9 0.1 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAG05514.1 - 1.4e-20 73.0 0.1 3.3e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAG05514.1 - 2.1e-20 72.9 0.0 4.4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG05514.1 - 1.1e-12 47.7 0.0 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG05514.1 - 1.1e-05 25.5 0.2 0.03 14.4 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 OAG05514.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 OAG05514.1 - 0.064 12.2 0.2 0.19 10.7 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 OAG05514.1 - 0.13 11.3 0.1 0.3 10.1 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain THOC2_N PF16134.5 OAG05515.1 - 4.8e-202 673.0 0.0 6.9e-202 672.5 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 OAG05515.1 - 3e-57 194.1 2.0 6.1e-57 193.1 2.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 OAG05515.1 - 1.3e-18 66.8 0.0 3.3e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Glyco_hydro_18 PF00704.28 OAG05516.1 - 3e-64 217.7 0.0 3.6e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 VTC PF09359.10 OAG05517.1 - 0.0021 17.5 0.0 0.0074 15.7 0.0 1.8 2 0 0 2 2 2 1 VTC domain MaoC_dehydratas PF01575.19 OAG05517.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain Ribosomal_L23eN PF03939.13 OAG05518.1 - 9.4e-27 93.0 8.5 9.4e-27 93.0 8.5 1.9 1 1 1 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 OAG05518.1 - 4.5e-14 52.6 0.5 4.5e-14 52.6 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 Bmt2 PF11968.8 OAG05519.1 - 1.5e-85 286.6 0.0 1.9e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 OAG05519.1 - 0.0043 16.9 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_1 PF00175.21 OAG05520.1 - 6.3e-31 107.2 0.0 1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG05520.1 - 3.4e-28 97.9 0.0 5.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 OAG05520.1 - 1.9e-20 72.8 0.3 3.2e-20 72.0 0.3 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAG05520.1 - 5.3e-06 26.6 0.0 3.7e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAG05520.1 - 0.0045 17.2 0.0 0.093 13.0 0.0 2.2 1 1 1 2 2 2 1 Siderophore-interacting FAD-binding domain p450 PF00067.22 OAG05521.1 - 1.5e-71 241.5 0.0 1.8e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4345 PF14248.6 OAG05522.1 - 1.5 8.8 8.6 0.23 11.3 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4345) NnrS PF05940.12 OAG05522.1 - 3.5 6.9 11.2 10 5.4 4.4 2.1 1 1 1 2 2 2 0 NnrS protein DUF3290 PF11694.8 OAG05522.1 - 6.3 6.8 10.3 0.17 11.9 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) STE3 PF02076.15 OAG05523.1 - 2.5e-79 266.5 19.5 3.2e-79 266.2 19.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor TssN PF17555.2 OAG05523.1 - 3.8 6.8 9.4 7.1 5.9 9.4 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN Pkinase PF00069.25 OAG05525.1 - 5.5e-58 196.4 0.0 9.9e-52 175.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG05525.1 - 1.5e-28 99.8 0.0 6.8e-26 91.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OAG05525.1 - 3.7e-06 26.4 0.1 4.1e-05 23.0 0.0 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG05525.1 - 0.00042 19.2 0.0 0.00068 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAG05525.1 - 0.00058 19.3 0.0 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAG05525.1 - 0.0023 17.9 0.1 0.0084 16.0 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OAG05525.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UQ_con PF00179.26 OAG05526.1 - 4.2e-43 146.4 0.0 5.4e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 OAG05526.1 - 2.6e-05 23.9 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain FXa_inhibition PF14670.6 OAG05527.1 - 0.16 12.3 0.4 0.16 12.3 0.4 2.1 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site AAA PF00004.29 OAG05528.1 - 5.8e-41 140.0 0.0 1.1e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG05528.1 - 1.6e-11 43.8 0.3 3.3e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OAG05528.1 - 1.3e-09 37.9 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OAG05528.1 - 5.6e-06 26.6 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAG05528.1 - 1.1e-05 25.5 0.1 3.8e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAG05528.1 - 1.5e-05 24.3 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAG05528.1 - 2.3e-05 24.7 0.8 0.0051 17.1 0.2 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAG05528.1 - 0.00024 21.5 0.2 0.0015 18.9 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OAG05528.1 - 0.00028 20.6 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAG05528.1 - 0.0033 17.7 0.0 0.009 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG05528.1 - 0.0088 16.6 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG05528.1 - 0.011 16.0 0.1 0.03 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 OAG05528.1 - 0.015 14.6 0.1 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 OAG05528.1 - 0.019 14.7 0.2 0.04 13.6 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 OAG05528.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAG05528.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG05528.1 - 0.028 14.3 0.1 0.63 9.9 0.1 2.4 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 OAG05528.1 - 0.029 13.7 0.2 0.53 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 OAG05528.1 - 0.058 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 OAG05528.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAG05528.1 - 0.086 12.1 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 OAG05528.1 - 0.11 12.1 1.0 0.63 9.6 0.4 2.4 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAG05528.1 - 0.16 11.1 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OAG05528.1 - 0.17 11.3 0.5 0.51 9.7 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OAG05528.1 - 0.18 11.3 0.1 0.48 9.9 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Prot_ATP_OB_N PF17758.1 OAG05528.1 - 0.2 11.3 0.9 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain ABC_tran PF00005.27 OAG05528.1 - 0.22 12.0 0.6 1.2 9.6 0.6 2.3 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAG05528.1 - 0.43 10.3 2.7 0.31 10.7 0.3 2.1 2 1 0 2 2 2 0 AAA domain KIF1B PF12423.8 OAG05529.1 - 0.073 13.5 0.4 0.2 12.1 0.4 1.8 1 0 0 1 1 1 0 Kinesin protein 1B Cyclin_C_2 PF16899.5 OAG05530.1 - 1.5e-25 89.6 0.1 2.6e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_N PF00134.23 OAG05530.1 - 0.00016 21.4 0.1 0.00048 19.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain MFS_1 PF07690.16 OAG05531.1 - 2e-27 96.1 35.4 3.2e-27 95.4 35.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RicinB_lectin_2 PF14200.6 OAG05534.1 - 0.028 15.2 1.5 0.028 15.2 1.5 2.3 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Atg14 PF10186.9 OAG05534.1 - 0.04 13.0 18.1 0.058 12.5 18.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LAP1C PF05609.12 OAG05534.1 - 0.24 10.4 17.4 0.35 9.9 17.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SlyX PF04102.12 OAG05534.1 - 2.6 8.7 19.0 0.12 13.0 4.4 2.9 1 1 2 3 3 3 0 SlyX V_ATPase_I PF01496.19 OAG05534.1 - 3.6 5.4 11.6 5.5 4.8 11.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 OAG05534.1 - 4.7 6.0 9.8 6.3 5.6 9.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 OAG05534.1 - 7.1 5.9 26.7 11 5.3 26.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Beta-lactamase PF00144.24 OAG05536.1 - 6e-37 127.6 0.2 8.5e-37 127.1 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase VCBS PF13517.6 OAG05537.1 - 1.4e-38 131.3 65.4 1.3e-11 44.9 2.3 8.9 3 2 7 10 10 10 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 OAG05537.1 - 1.5e-13 51.6 0.9 4.4e-13 50.0 0.5 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG05537.1 - 1.5e-09 38.1 0.1 2.8e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 OAG05537.1 - 1.1e-06 28.6 31.8 0.0022 18.1 0.4 6.9 6 0 0 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 OAG05537.1 - 1.4e-06 27.8 9.2 0.67 9.3 0.1 6.3 3 2 3 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region PliI PF16743.5 OAG05537.1 - 0.018 14.8 1.5 6.4 6.5 0.1 4.3 5 0 0 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme Dockerin_1 PF00404.18 OAG05537.1 - 2.6 8.3 18.1 3.7 7.8 0.1 5.2 6 0 0 6 6 6 0 Dockerin type I domain EF-hand_1 PF00036.32 OAG05537.1 - 4 7.2 14.5 6.6 6.5 0.0 4.9 6 0 0 6 6 6 0 EF hand MFS_1 PF07690.16 OAG05538.1 - 1.7e-39 135.8 36.7 1.7e-39 135.8 36.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG05538.1 - 2.6e-09 36.5 6.7 2.6e-09 36.5 6.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter S10_plectin PF03501.15 OAG05538.1 - 0.026 14.6 0.4 0.055 13.5 0.4 1.4 1 0 0 1 1 1 0 Plectin/S10 domain DUF4191 PF13829.6 OAG05538.1 - 0.16 11.3 9.0 0.33 10.3 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Fungal_trans PF04082.18 OAG05539.1 - 8.8e-16 57.7 0.0 1.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG05539.1 - 6.1e-08 32.7 6.4 9.5e-08 32.0 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 OAG05540.1 - 3.5e-48 164.3 0.0 4.5e-33 114.4 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family FAD_binding_4 PF01565.23 OAG05541.1 - 1e-26 93.3 0.3 1.9e-26 92.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG05541.1 - 5.4e-06 26.4 0.7 1.2e-05 25.3 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 OAG05542.1 - 6.6e-26 91.0 0.1 1e-25 90.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05542.1 - 4.2e-15 55.9 0.2 5.1e-15 55.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG05542.1 - 1.1e-05 25.4 0.0 1.5e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG05542.1 - 0.00048 20.1 0.1 0.00058 19.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG05542.1 - 0.0042 16.7 0.0 0.013 15.1 0.0 1.7 1 1 1 2 2 2 1 NmrA-like family Epimerase PF01370.21 OAG05542.1 - 0.0072 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2955 PF11168.8 OAG05542.1 - 0.041 13.7 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) DUF1611 PF07755.11 OAG05542.1 - 0.055 12.8 1.5 2 7.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_C) P-loop domain p450 PF00067.22 OAG05543.1 - 2e-58 198.3 0.0 2.6e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_tail_U PF06141.11 OAG05543.1 - 0.19 12.1 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein U Abhydrolase_1 PF00561.20 OAG05544.1 - 1.6e-11 44.4 0.0 5.4e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG05544.1 - 2.8e-11 43.1 0.0 2.6e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 OAG05544.1 - 5e-09 35.3 0.0 2.7e-06 26.3 0.0 2.6 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAG05544.1 - 7.8e-08 33.2 0.0 1e-07 32.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG05544.1 - 8.4e-08 31.9 0.0 0.00031 20.3 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAG05544.1 - 7e-05 22.5 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 OAG05544.1 - 0.00082 19.3 0.0 0.003 17.5 0.0 1.9 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OAG05544.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAG05544.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 OAG05545.1 - 6.1e-62 209.5 0.2 6e-60 202.9 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 OAG05545.1 - 3.1e-54 184.2 0.0 5.8e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAG05545.1 - 3.8e-50 170.3 0.8 1.3e-49 168.5 0.3 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 OAG05545.1 - 8.7e-44 150.3 0.1 2.5e-43 148.8 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG05545.1 - 9.9e-30 103.0 0.2 4.1e-29 101.0 0.2 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 OAG05545.1 - 1.4e-18 67.1 0.0 4.1e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG05545.1 - 1.4e-17 65.0 0.0 5.6e-17 63.0 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 OAG05545.1 - 1.5e-16 60.9 0.0 3.3e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 OAG05545.1 - 1.3e-08 34.7 1.1 3e-08 33.5 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 OAG05545.1 - 5.8e-06 26.6 0.0 1.7e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OAG05545.1 - 2.4e-05 23.9 0.1 2.4e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase SAT PF16073.5 OAG05545.1 - 0.00035 20.4 0.2 0.027 14.2 0.0 2.7 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short_C2 PF13561.6 OAG05545.1 - 0.00039 20.1 0.1 0.00088 18.9 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TRAPP PF04051.16 OAG05547.1 - 3.8e-39 133.7 0.0 8.3e-39 132.6 0.0 1.5 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_C PF02866.18 OAG05548.1 - 4.1e-46 157.0 0.0 6.3e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAG05548.1 - 5.4e-46 156.2 0.1 7.3e-46 155.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG05548.1 - 4.2e-05 22.7 0.0 6.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG05548.1 - 0.00023 21.1 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 OAG05548.1 - 0.015 14.6 0.0 0.065 12.5 0.0 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 OAG05548.1 - 0.033 13.7 0.1 1.8 8.1 0.1 2.3 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase CBFD_NFYB_HMF PF00808.23 OAG05550.1 - 2.8e-19 69.1 0.5 4e-19 68.7 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG05550.1 - 8.8e-15 55.2 0.2 1.4e-14 54.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 OAG05550.1 - 0.039 14.3 0.2 0.084 13.2 0.0 1.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Fcf2 PF08698.11 OAG05551.1 - 2.5e-38 130.4 0.3 2.5e-38 130.4 0.3 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing SVIP PF15811.5 OAG05551.1 - 1.2 9.6 6.1 2 8.9 1.1 2.5 2 0 0 2 2 2 0 Small VCP/p97-interacting protein PNP_UDP_1 PF01048.20 OAG05552.1 - 1.3e-56 191.5 1.4 2.1e-56 190.8 1.4 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.22 OAG05553.1 - 2.1e-23 82.4 0.0 5.3e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MFS_1 PF07690.16 OAG05554.1 - 9.5e-30 103.7 30.5 9.5e-30 103.7 30.5 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG05554.1 - 8.3e-08 31.1 3.9 8.3e-08 31.1 3.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG05554.1 - 4.5e-06 25.8 31.8 0.00056 18.9 31.8 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter FAA_hydrolase PF01557.18 OAG05555.1 - 4.4e-47 160.6 0.0 6e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG05555.1 - 4.2e-17 62.3 0.0 8.4e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Cupin_2 PF07883.11 OAG05556.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Peptidase_S15 PF02129.18 OAG05557.1 - 1.5e-41 142.8 0.2 2e-41 142.4 0.2 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG05557.1 - 5.9e-41 140.9 0.1 1e-40 140.1 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 OAG05557.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aldedh PF00171.22 OAG05558.1 - 7.3e-13 47.8 0.0 3.9e-10 38.8 0.0 2.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family GARS_C PF02843.16 OAG05558.1 - 0.024 14.9 0.1 0.068 13.5 0.1 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain FAD_binding_3 PF01494.19 OAG05560.1 - 1.7e-22 80.2 0.7 1.2e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain ADC PF06314.11 OAG05560.1 - 8.9e-16 58.2 0.1 2.1e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 OAG05560.1 - 5.1e-08 32.5 0.1 2.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG05560.1 - 1.4e-07 31.5 1.0 1.6e-06 28.0 0.4 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG05560.1 - 2.5e-07 30.8 0.2 5.3e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG05560.1 - 6.1e-07 28.9 0.5 9.4e-07 28.2 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG05560.1 - 0.00021 20.8 0.1 0.00035 20.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG05560.1 - 0.0011 18.1 0.2 0.0018 17.5 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG05560.1 - 0.0014 17.8 0.1 1.4 7.9 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 OAG05560.1 - 0.0028 16.4 0.6 0.0046 15.7 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAG05560.1 - 0.0029 18.1 0.1 0.0072 16.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG05560.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 OAG05560.1 - 0.017 14.4 0.2 0.031 13.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 OAG05560.1 - 0.02 13.7 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 OAG05560.1 - 0.025 13.5 0.3 0.52 9.1 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 OAG05560.1 - 0.09 12.0 0.1 3.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAG05560.1 - 0.2 10.9 0.1 0.45 9.7 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 OAG05561.1 - 1.1e-12 47.6 1.2 1.9e-12 46.8 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG05561.1 - 1.2e-08 35.0 13.3 1.4e-06 28.5 4.9 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG05561.1 - 6.2e-08 32.7 18.6 0.00031 21.0 4.7 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 OAG05561.1 - 1.6e-06 28.1 12.3 1.6e-06 28.1 12.3 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 OAG05561.1 - 0.002 18.8 11.2 0.012 16.4 3.4 3.8 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAG05561.1 - 0.012 15.5 0.6 0.012 15.5 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 OAG05561.1 - 0.014 15.3 2.2 0.014 15.3 2.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 OAG05561.1 - 0.019 15.3 4.8 0.019 15.3 4.8 2.5 3 0 0 3 3 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OAG05561.1 - 0.031 14.7 5.6 0.11 12.9 0.9 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Viral_DNA_bp PF00747.17 OAG05561.1 - 0.17 9.0 1.8 0.25 8.5 1.8 1.1 1 0 0 1 1 1 0 ssDNA binding protein zf-C2H2_11 PF16622.5 OAG05561.1 - 1.3 8.9 7.5 3.9 7.3 2.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type LigB PF02900.18 OAG05562.1 - 1.1e-09 37.8 0.1 1.6e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mg_trans_NIPA PF05653.14 OAG05563.1 - 5e-64 216.2 3.3 1.4e-60 204.9 2.8 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 OAG05563.1 - 0.0024 18.0 22.6 0.0097 16.1 0.8 3.7 3 1 0 3 3 3 2 EamA-like transporter family Herpes_gE PF02480.16 OAG05563.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CPP1-like PF11833.8 OAG05563.1 - 0.28 10.8 4.0 0.67 9.6 3.3 2.0 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ctr PF04145.15 OAG05563.1 - 0.3 11.7 0.0 0.3 11.7 0.0 2.6 4 1 0 4 4 4 0 Ctr copper transporter family CD20 PF04103.15 OAG05563.1 - 0.77 9.8 0.0 0.77 9.8 0.0 3.5 5 0 0 5 5 5 0 CD20-like family Trp_oprn_chp PF09534.10 OAG05563.1 - 1.1 9.1 10.7 1.8 8.4 0.9 3.4 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amidohydro_2 PF04909.14 OAG05565.1 - 4.9e-41 141.4 0.4 5.7e-41 141.2 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase MIF4G_like PF09088.11 OAG05566.1 - 2.7e-79 265.4 0.8 5.4e-79 264.4 0.8 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 OAG05566.1 - 7e-65 219.1 0.1 1.1e-64 218.5 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 OAG05566.1 - 0.2 11.2 0.4 0.68 9.5 0.1 2.1 2 0 0 2 2 2 0 MIF4G domain Pkinase PF00069.25 OAG05568.1 - 1.6e-65 221.1 0.0 1.9e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG05568.1 - 1.4e-24 86.8 0.0 1.9e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG05568.1 - 1.1e-06 28.2 0.0 3.7e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAG05568.1 - 0.0017 18.3 0.2 0.0097 15.9 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG05568.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OAG05568.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FSH1 PF03959.13 OAG05570.1 - 1e-50 172.3 0.0 1.2e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OAG05570.1 - 5.7e-06 26.3 0.1 1.1 9.1 0.1 3.0 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Thioesterase PF00975.20 OAG05570.1 - 0.067 13.3 0.3 0.15 12.1 0.3 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 OAG05570.1 - 2.2 8.8 7.2 14 6.2 0.1 2.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF4298 PF14131.6 OAG05572.1 - 0.25 11.3 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Gti1_Pac2 PF09729.9 OAG05574.1 - 1.5e-53 181.6 0.2 3.5e-53 180.4 0.0 1.7 2 0 0 2 2 2 1 Gti1/Pac2 family Abhydrolase_5 PF12695.7 OAG05575.1 - 3.2e-05 23.8 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG05575.1 - 0.00047 20.2 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Lipase_3 PF01764.25 OAG05575.1 - 0.092 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 OAG05575.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Flu_NS2 PF00601.19 OAG05576.1 - 0.014 15.7 3.7 0.025 14.8 3.5 1.6 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) DUF4477 PF14780.6 OAG05576.1 - 0.02 14.5 4.2 0.038 13.6 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) DUF2207 PF09972.9 OAG05576.1 - 0.022 13.5 0.0 0.027 13.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RRM_2 PF04059.12 OAG05577.1 - 2.5e-27 94.9 0.0 4.5e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 OAG05577.1 - 4.6e-06 26.3 0.0 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dodecin PF07311.12 OAG05578.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Dodecin Sugar_tr PF00083.24 OAG05580.1 - 3.8e-77 260.1 20.7 4.3e-77 259.9 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG05580.1 - 8.5e-20 71.0 47.9 1.4e-17 63.6 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5367 PF17329.2 OAG05580.1 - 0.18 12.0 9.5 0.43 10.7 0.8 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5367) HlyIII PF03006.20 OAG05580.1 - 7.5 6.2 13.1 0.55 9.9 5.4 2.6 3 0 0 3 3 3 0 Haemolysin-III related RAI1 PF08652.11 OAG05581.1 - 3.7e-20 71.9 0.0 9.5e-20 70.6 0.0 1.7 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease PRCC PF10253.9 OAG05582.1 - 0.061 14.1 1.0 0.071 13.9 1.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MCPVI PF02993.14 OAG05582.1 - 8.8 6.1 8.0 4.6 7.0 0.0 2.0 1 1 1 2 2 2 0 Minor capsid protein VI Sec15 PF04091.12 OAG05583.1 - 3.5e-104 348.6 0.2 3.5e-104 348.6 0.2 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 OAG05583.1 - 0.00027 20.8 4.3 0.00027 20.8 4.3 3.0 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain COG5 PF10392.9 OAG05583.1 - 0.002 18.3 5.1 0.0032 17.6 1.6 2.9 3 0 0 3 3 3 1 Golgi transport complex subunit 5 TetR_C_30 PF17939.1 OAG05583.1 - 0.012 15.9 0.0 0.037 14.2 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Vps54_N PF10475.9 OAG05583.1 - 0.07 12.4 5.2 0.042 13.1 3.0 1.8 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 OAG05583.1 - 0.11 12.6 7.9 0.052 13.6 4.1 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoLp-III PF07464.11 OAG05583.1 - 0.38 10.8 4.4 0.85 9.7 1.0 2.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Sacchrp_dh_C PF16653.5 OAG05584.1 - 7.9e-93 311.4 0.0 1.9e-92 310.1 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 OAG05584.1 - 1.6e-25 89.8 0.8 2.5e-25 89.2 0.8 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG05584.1 - 7.7e-08 32.5 1.1 2.7e-07 30.7 1.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OAG05584.1 - 4e-05 23.0 1.1 6.4e-05 22.3 1.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 OAG05584.1 - 0.00018 21.2 0.3 0.0012 18.4 0.1 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_10 PF13460.6 OAG05584.1 - 0.00023 21.1 0.5 0.00035 20.5 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 OAG05584.1 - 0.0098 16.7 0.1 0.017 15.9 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 OAG05584.1 - 0.031 14.5 0.5 0.049 13.9 0.5 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 OAG05584.1 - 0.046 14.2 0.3 0.092 13.2 0.3 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 OAG05584.1 - 0.072 12.6 0.3 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG05584.1 - 0.087 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF410 PF04190.13 OAG05585.1 - 4.7e-88 295.3 0.0 5.6e-88 295.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Exo_endo_phos PF03372.23 OAG05587.1 - 2.8e-06 27.0 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 OAG05587.1 - 7.5e-05 22.6 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DCP1 PF06058.13 OAG05588.1 - 5.7e-27 94.0 0.0 1.7e-26 92.5 0.0 1.6 2 0 0 2 2 2 1 Dcp1-like decapping family TMEM37 PF15108.6 OAG05588.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family MRP-S33 PF08293.11 OAG05589.1 - 1.1e-28 99.3 0.0 1.4e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Bac_globin PF01152.21 OAG05589.1 - 0.006 16.7 0.0 0.0066 16.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial-like globin Ribonuclease_3 PF00636.26 OAG05590.1 - 1.4e-13 51.4 4.2 2.6e-13 50.5 0.0 3.0 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAG05590.1 - 2.7e-12 47.0 0.0 2.7e-12 47.0 0.0 2.1 3 0 0 3 3 3 1 Ribonuclease-III-like dsrm PF00035.26 OAG05590.1 - 0.014 16.0 0.0 0.063 14.0 0.0 2.2 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF3568 PF12092.8 OAG05590.1 - 0.2 11.7 2.2 0.67 10.0 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Clr2 PF10383.9 OAG05590.1 - 0.26 12.0 2.7 2 9.2 1.1 2.9 2 2 0 2 2 2 0 Transcription-silencing protein Clr2 AMP-binding PF00501.28 OAG05591.1 - 9.5e-64 215.5 0.0 1.2e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG05591.1 - 1.4e-05 26.0 0.5 2.8e-05 25.0 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OTT_1508_deam PF14441.6 OAG05592.1 - 1.3e-14 53.9 0.0 3.2e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase GARS_A PF01071.19 OAG05593.1 - 3.4e-84 281.5 0.0 5.2e-84 280.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 OAG05593.1 - 6.6e-36 123.0 0.2 4.9e-35 120.2 0.0 2.3 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 OAG05593.1 - 1.5e-27 95.6 1.2 3.8e-27 94.4 1.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 OAG05593.1 - 6.8e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG05593.1 - 7.1e-05 22.9 0.0 0.00027 21.0 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 OAG05593.1 - 0.00029 20.4 0.2 0.00072 19.1 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 OAG05593.1 - 0.023 14.3 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 OAG05593.1 - 0.091 12.0 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 OAG05593.1 - 0.18 11.6 0.0 32 4.3 0.0 2.8 3 0 0 3 3 3 0 ATP-grasp in the biosynthetic pathway with Ter operon NACHT PF05729.12 OAG05595.1 - 3.1e-10 40.2 0.0 5.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG05595.1 - 8.7e-07 29.5 0.0 2.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 OAG05595.1 - 0.00048 19.4 0.0 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 OAG05595.1 - 0.0012 19.3 0.0 0.007 16.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Goodbye PF17109.5 OAG05595.1 - 0.013 16.0 0.3 0.17 12.4 0.1 2.8 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 OAG05595.1 - 0.013 15.8 0.0 0.068 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OAG05595.1 - 0.015 14.6 0.4 0.58 9.3 0.1 2.6 1 1 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 OAG05595.1 - 0.042 14.4 0.1 0.33 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG05595.1 - 0.064 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG05595.1 - 0.073 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 OAG05595.1 - 0.09 12.4 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 OAG05595.1 - 0.11 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 OAG05595.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 OAG05595.1 - 0.15 12.1 0.2 0.76 9.8 0.0 2.3 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SNF2_N PF00176.23 OAG05596.1 - 3.1e-60 203.7 0.0 4.4e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG05596.1 - 1.3e-12 48.0 0.0 1.8e-11 44.4 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG05596.1 - 1.1e-07 31.7 0.0 3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG05596.1 - 1.3e-07 31.8 0.0 5.9e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG05596.1 - 0.0063 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 OAG05596.1 - 0.0063 16.3 2.7 0.018 14.9 2.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG05596.1 - 0.062 13.3 7.0 0.57 10.2 7.7 2.2 1 1 1 2 2 2 0 zinc-RING finger domain AAA_34 PF13872.6 OAG05596.1 - 0.078 11.9 0.4 0.36 9.7 0.4 1.9 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-C3HC4 PF00097.25 OAG05596.1 - 0.11 12.4 6.9 0.36 10.7 7.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG05596.1 - 0.19 11.8 4.6 0.64 10.1 4.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 OAG05596.1 - 0.46 10.9 8.3 0.3 11.5 6.0 1.9 2 0 0 2 2 2 0 Ring finger domain MFS_1 PF07690.16 OAG05597.1 - 1.8e-25 89.6 24.4 1.8e-25 89.6 24.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG05597.1 - 4.9e-06 25.7 6.8 4.9e-06 25.7 6.8 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Amidohydro_3 PF07969.11 OAG05598.1 - 1.1e-67 229.5 5.4 1.3e-67 229.3 5.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG05598.1 - 8e-12 45.1 0.3 1.3e-07 31.3 0.3 3.1 2 1 0 2 2 2 2 Amidohydrolase family SpoVS PF04232.12 OAG05598.1 - 0.0089 15.7 2.8 0.021 14.6 2.8 1.5 1 0 0 1 1 1 1 Stage V sporulation protein S (SpoVS) DUF1542 PF07564.11 OAG05598.1 - 0.057 13.5 1.5 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) F-box PF00646.33 OAG05600.1 - 0.081 12.8 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 F-box domain Pro_isomerase PF00160.21 OAG05601.1 - 6.4e-42 143.5 0.0 1.3e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF5082 PF16888.5 OAG05601.1 - 0.13 12.5 0.4 0.24 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) MBOAT PF03062.19 OAG05602.1 - 3.2e-54 184.6 4.4 5.8e-54 183.7 4.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.11 OAG05602.1 - 0.091 13.1 0.2 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) Glyco_hydro_61 PF03443.14 OAG05603.1 - 4e-58 196.7 0.9 4.8e-58 196.5 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GMC_oxred_C PF05199.13 OAG05604.1 - 5.2e-29 101.6 0.0 1e-28 100.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG05604.1 - 6.7e-28 97.9 0.0 1.2e-26 93.9 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAG05604.1 - 0.011 15.0 0.0 0.031 13.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG05604.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG05604.1 - 0.023 14.0 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG05604.1 - 0.029 13.4 0.3 0.05 12.7 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG05604.1 - 0.039 14.2 0.2 0.089 13.0 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG05604.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Histone PF00125.24 OAG05606.1 - 5.1e-44 149.8 1.1 8.4e-44 149.1 1.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAG05606.1 - 5.2e-08 33.2 0.1 8.3e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAG05606.1 - 2.2e-05 24.6 0.1 3.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAG05606.1 - 0.0023 18.2 0.5 0.0043 17.3 0.5 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAG05606.1 - 0.0076 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG05606.1 - 0.099 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DER1 PF04511.15 OAG05607.1 - 3.2e-49 167.5 6.7 3.6e-49 167.3 6.7 1.0 1 0 0 1 1 1 1 Der1-like family Cation_ATPase_C PF00689.21 OAG05607.1 - 0.67 9.6 11.0 1.5 8.5 0.7 2.3 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus S1-P1_nuclease PF02265.16 OAG05608.1 - 6.9e-74 248.9 0.1 9.7e-74 248.4 0.1 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease zf-CCHC PF00098.23 OAG05608.1 - 0.58 10.3 4.4 0.75 10.0 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 OAG05609.1 - 0.0064 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2944 PF11161.8 OAG05609.1 - 0.02 14.8 0.2 0.077 12.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) DUF2684 PF10885.8 OAG05609.1 - 0.13 12.4 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) F-box-like PF12937.7 OAG05610.1 - 1.7e-05 24.6 0.4 4.3e-05 23.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG05610.1 - 0.86 9.6 4.1 0.56 10.2 0.4 2.6 3 0 0 3 3 3 0 F-box domain F5_F8_type_C PF00754.25 OAG05611.1 - 3.5e-45 153.2 10.4 2.8e-22 79.2 1.4 2.7 2 0 0 2 2 2 2 F5/8 type C domain DUF1929 PF09118.11 OAG05611.1 - 4.6e-24 84.5 0.3 1.4e-23 83.0 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 OAG05611.1 - 5.2e-16 58.3 6.9 1.4e-05 25.2 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OAG05611.1 - 2e-15 56.1 6.1 1.7e-05 24.3 0.0 4.9 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OAG05611.1 - 1.5e-08 34.3 0.1 0.71 9.9 0.1 5.8 5 0 0 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.11 OAG05611.1 - 4.2e-07 29.4 0.8 0.00093 18.5 0.1 3.1 2 1 0 3 3 3 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 OAG05611.1 - 7.8e-06 25.8 11.4 4.8e-05 23.3 0.1 5.6 6 0 0 6 6 6 1 Galactose oxidase, central domain DUF3999 PF13163.6 OAG05611.1 - 0.007 15.6 0.1 0.14 11.4 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3999) Kelch_3 PF13415.6 OAG05611.1 - 0.069 13.5 7.6 0.55 10.6 0.1 4.6 4 0 0 4 4 4 0 Galactose oxidase, central domain SKG6 PF08693.10 OAG05612.1 - 0.0099 15.3 0.7 0.018 14.4 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2207 PF09972.9 OAG05612.1 - 0.047 12.5 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PTP_tm PF18861.1 OAG05612.1 - 0.11 12.5 0.4 0.24 11.4 0.3 1.6 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J 3HCDH_N PF02737.18 OAG05613.1 - 2.9e-48 164.2 0.0 4.3e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG05613.1 - 2.8e-13 50.3 0.0 6.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldl_recept_b PF00058.17 OAG05613.1 - 3.8e-12 46.5 0.0 0.39 11.3 0.0 5.0 4 0 0 4 4 4 4 Low-density lipoprotein receptor repeat class B 2-Hacid_dh_C PF02826.19 OAG05613.1 - 0.00019 20.9 0.0 0.0011 18.4 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SGL PF08450.12 OAG05613.1 - 0.00044 19.9 0.0 7.4 6.1 0.0 2.9 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NAD_Gly3P_dh_N PF01210.23 OAG05613.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 OAG05613.1 - 0.0019 17.8 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 OAG05613.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Str_synth PF03088.16 OAG05613.1 - 0.015 15.4 0.0 13 6.0 0.0 3.5 2 1 1 3 3 3 0 Strictosidine synthase NAD_binding_7 PF13241.6 OAG05613.1 - 0.023 15.1 0.0 0.32 11.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Metal_CEHH PF14455.6 OAG05613.1 - 0.032 13.9 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 Predicted metal binding domain ApbA PF02558.16 OAG05613.1 - 0.035 13.8 0.1 0.098 12.3 0.1 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 OAG05613.1 - 0.036 13.6 0.1 0.28 10.8 0.1 2.3 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OAG05613.1 - 0.073 13.7 0.0 0.25 12.0 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 OAG05613.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OAG05613.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Arylesterase PF01731.20 OAG05613.1 - 0.14 12.3 0.0 13 6.1 0.0 2.7 2 0 0 2 2 2 0 Arylesterase Pyr_redox PF00070.27 OAG05613.1 - 0.15 12.6 0.0 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 OAG05614.1 - 4.3e-40 138.0 0.4 3.4e-39 135.0 0.3 2.0 2 0 0 2 2 2 1 CoA-transferase family III RRM_1 PF00076.22 OAG05615.1 - 1.1e-36 124.5 0.1 4.1e-19 68.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG05615.1 - 7.4e-05 22.8 0.0 0.077 13.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OAG05615.1 - 0.0021 17.6 0.3 0.46 10.1 0.1 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 OAG05615.1 - 0.0078 15.9 0.9 3.3 7.5 0.1 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Cas_Cas2CT1978 PF09707.10 OAG05615.1 - 0.023 14.7 0.1 0.3 11.2 0.1 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_occluded PF16842.5 OAG05615.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Tom7 PF08038.12 OAG05616.1 - 1.9e-22 78.6 0.1 2.2e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 TOM7 family SesA PF17107.5 OAG05617.1 - 0.012 15.8 0.3 0.037 14.2 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SlyX PF04102.12 OAG05617.1 - 0.24 12.0 1.9 0.49 11.1 0.2 2.3 2 0 0 2 2 2 0 SlyX IBB PF01749.20 OAG05618.1 - 0.02 15.3 3.4 0.037 14.5 3.4 1.3 1 0 0 1 1 1 0 Importin beta binding domain Hep_core_N PF08290.11 OAG05619.1 - 0.074 13.0 0.4 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger DnaJ PF00226.31 OAG05620.1 - 1.5e-13 50.7 0.0 3.5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain UPF0561 PF10573.9 OAG05620.1 - 0.28 11.3 5.7 0.048 13.8 1.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 bZIP_2 PF07716.15 OAG05621.1 - 8.7e-10 38.5 16.3 1.3e-09 37.9 16.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAG05621.1 - 0.0027 17.8 14.9 0.0027 17.8 14.9 1.5 1 1 0 1 1 1 1 bZIP transcription factor UPF0449 PF15136.6 OAG05621.1 - 0.05 14.1 3.9 0.11 12.9 3.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 JAKMIP_CC3 PF16034.5 OAG05621.1 - 0.25 11.2 11.1 0.28 11.1 9.9 1.5 1 1 0 1 1 1 0 JAKMIP CC3 domain CFEM PF05730.11 OAG05622.1 - 2.1e-11 43.8 12.2 2.4e-11 43.5 12.2 1.1 1 0 0 1 1 1 1 CFEM domain TIL PF01826.17 OAG05622.1 - 0.057 13.7 6.9 0.081 13.2 6.9 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain FXa_inhibition PF14670.6 OAG05622.1 - 0.51 10.7 6.4 6.4 7.2 6.4 2.2 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site Antimicrobial25 PF16839.5 OAG05622.1 - 0.7 10.0 7.4 3 8.0 6.9 2.0 1 1 1 2 2 2 0 Nematode antimicrobial peptide Acetyltransf_1 PF00583.25 OAG05623.1 - 8.6e-08 32.4 0.1 1.4e-07 31.8 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG05623.1 - 2.9e-06 27.3 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG05623.1 - 9.2e-06 26.0 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG05623.1 - 0.00094 19.3 0.1 0.033 14.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG05623.1 - 0.18 11.8 0.0 0.59 10.1 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein DIOX_N PF14226.6 OAG05625.1 - 7.2e-19 68.7 0.3 1.4e-18 67.8 0.3 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG05625.1 - 5.2e-12 46.1 0.0 2e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG05626.1 - 9.5e-30 103.7 61.6 1.5e-15 57.0 29.9 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Phosphodiest PF01663.22 OAG05627.1 - 2.7e-14 53.5 0.9 3e-11 43.5 0.9 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG05627.1 - 0.00042 19.8 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Sulfatase PigN PF04987.14 OAG05627.1 - 0.0019 17.2 1.3 0.0019 17.2 1.3 2.3 2 1 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) FUN14 PF04930.15 OAG05628.1 - 5.4e-09 36.4 0.3 8.7e-09 35.7 0.3 1.3 1 0 0 1 1 1 1 FUN14 family Importin_rep PF18773.1 OAG05629.1 - 6.9e-07 28.9 0.1 1.2e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Importin 13 repeat UME PF08064.13 OAG05629.1 - 0.015 15.2 0.0 23 5.0 0.0 4.5 2 1 0 2 2 2 0 UME (NUC010) domain Creatinase_N_2 PF16189.5 OAG05630.1 - 1e-52 178.5 0.4 8.4e-52 175.5 0.1 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OAG05630.1 - 1.1e-45 155.9 0.0 1.7e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 OAG05630.1 - 2.8e-21 76.6 0.1 2.3e-18 67.1 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 OAG05630.1 - 4.3e-19 68.3 0.1 1.6e-18 66.5 0.1 2.1 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 SOR_SNZ PF01680.17 OAG05631.1 - 2.4e-107 357.4 3.6 4e-107 356.7 3.6 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAG05631.1 - 4.1e-09 36.1 4.5 2.1e-06 27.3 0.2 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAG05631.1 - 0.00056 19.1 0.2 0.31 10.1 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OAG05631.1 - 0.0011 18.5 0.3 0.013 15.0 0.0 2.3 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 OAG05631.1 - 0.0025 17.0 0.1 0.31 10.1 0.0 3.3 3 1 1 4 4 4 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 OAG05631.1 - 0.0039 16.4 1.4 0.0088 15.2 0.1 2.2 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 OAG05631.1 - 0.0098 15.9 0.0 0.029 14.4 0.0 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 OAG05631.1 - 0.2 11.0 6.3 0.28 10.5 0.2 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Skp1 PF01466.19 OAG05632.1 - 6.3e-28 96.6 0.3 1e-27 96.0 0.3 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OAG05632.1 - 1.7e-21 76.1 0.3 4.4e-21 74.8 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_transf_22 PF03901.17 OAG05633.1 - 1.5e-60 205.6 25.7 1.9e-60 205.2 25.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Na_H_Exchanger PF00999.21 OAG05635.1 - 5.1e-73 246.1 33.8 6.3e-73 245.8 33.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 OAG05635.1 - 0.078 12.6 0.6 0.17 11.5 0.6 1.6 1 0 0 1 1 1 0 PepSY-associated TM region MFS_2 PF13347.6 OAG05636.1 - 8.4e-12 44.4 4.9 8.4e-12 44.4 4.9 3.2 4 0 0 4 4 4 2 MFS/sugar transport protein PUCC PF03209.15 OAG05636.1 - 3.4e-05 23.0 3.3 3.4e-05 23.0 3.3 2.1 3 0 0 3 3 3 1 PUCC protein DUF4064 PF13273.6 OAG05636.1 - 0.31 11.4 0.1 0.31 11.4 0.1 3.8 5 1 0 5 5 5 0 Protein of unknown function (DUF4064) SNF2_N PF00176.23 OAG05637.1 - 1.3e-73 247.8 1.2 1.3e-73 247.8 1.2 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 OAG05637.1 - 6.9e-22 77.3 1.1 2.2e-21 75.7 1.1 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 OAG05637.1 - 5e-20 71.9 6.1 1.2e-18 67.4 0.0 4.4 4 1 1 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.13 OAG05637.1 - 1.8e-15 57.0 17.3 1.8e-15 57.0 17.3 3.7 4 0 0 4 4 4 1 HSA ResIII PF04851.15 OAG05637.1 - 1.1e-10 41.8 0.0 1.1e-10 41.8 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SnAC PF14619.6 OAG05637.1 - 1.1e-10 41.9 0.1 1.1e-10 41.9 0.1 3.6 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 OAG05637.1 - 1.6e-10 40.5 3.5 5.7e-10 38.8 3.5 2.0 1 0 0 1 1 1 1 QLQ Chalcone_2 PF16035.5 OAG05637.1 - 0.32 10.8 8.7 1.2 8.9 8.7 2.1 1 0 0 1 1 1 0 Chalcone isomerase like DUF463 PF04317.12 OAG05638.1 - 0.032 13.2 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Cadherin_tail PF15974.5 OAG05638.1 - 0.042 14.2 0.6 0.096 13.0 0.6 1.5 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region AXE1 PF05448.12 OAG05638.1 - 0.067 11.9 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) ATG101 PF07855.12 OAG05640.1 - 9.5e-54 181.6 0.6 1.1e-53 181.4 0.6 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 CobD_Cbib PF03186.13 OAG05640.1 - 0.098 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 CobD/Cbib protein Sugar_tr PF00083.24 OAG05641.1 - 1.2e-106 357.3 22.8 1.4e-106 357.1 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG05641.1 - 2.8e-23 82.4 30.6 3.8e-15 55.7 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG05641.1 - 0.0002 20.1 21.6 0.0091 14.6 9.6 2.8 2 2 1 3 3 3 2 MFS/sugar transport protein ORC2 PF04084.14 OAG05642.1 - 1e-115 386.2 0.0 1.4e-115 385.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Laminin_EGF PF00053.24 OAG05643.1 - 0.38 10.9 5.6 0.37 11.0 4.5 1.5 1 1 0 1 1 1 0 Laminin EGF domain UCH_1 PF13423.6 OAG05644.1 - 1e-18 68.0 0.0 5.4e-08 32.8 0.0 2.7 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.21 OAG05645.1 - 6.2e-27 93.6 0.0 1.8e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAG05645.1 - 4.6e-11 42.9 0.0 9.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 SET PF00856.28 OAG05646.1 - 1.8e-13 51.2 0.0 1.3e-12 48.4 0.0 2.0 1 1 0 1 1 1 1 SET domain UbiA PF01040.18 OAG05648.1 - 6.3e-11 42.1 15.0 7e-11 41.9 15.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family HAD PF12710.7 OAG05649.1 - 0.0097 16.3 0.0 0.044 14.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box_4 PF15966.5 OAG05651.1 - 1.2e-07 31.5 0.4 3.9e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 OAG05651.1 - 9.2e-05 22.3 0.1 0.00018 21.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG05651.1 - 0.038 13.9 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box domain Melibiase_2 PF16499.5 OAG05653.1 - 4.2e-47 160.7 3.0 4.4e-47 160.6 1.1 2.0 2 0 0 2 2 2 1 Alpha galactosidase A Melibiase_C PF17801.1 OAG05653.1 - 9.2e-11 41.7 2.0 9.2e-11 41.7 2.0 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG05653.1 - 0.033 13.2 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Melibiase Tyrosinase PF00264.20 OAG05654.1 - 1e-46 160.0 1.1 1.5e-46 159.4 1.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Epimerase PF01370.21 OAG05655.1 - 1.8e-08 34.1 0.3 3e-07 30.2 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG05655.1 - 0.0006 20.1 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain MYEOV2 PF15004.6 OAG05655.1 - 0.0024 18.3 0.1 0.0048 17.3 0.1 1.5 1 0 0 1 1 1 1 Myeloma-overexpressed-like Semialdhyde_dh PF01118.24 OAG05655.1 - 0.019 15.4 0.0 0.067 13.6 0.0 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Thioredoxin_16 PF18569.1 OAG05655.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain RhoGEF PF00621.20 OAG05656.1 - 5.2e-07 30.1 0.3 8.5e-07 29.4 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain Tudor_4 PF18358.1 OAG05656.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain ABC_membrane PF00664.23 OAG05657.1 - 7e-81 271.9 33.0 3e-44 151.7 5.2 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG05657.1 - 1.1e-52 178.1 0.2 5.4e-30 104.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OAG05657.1 - 2.5e-08 33.6 4.9 0.0048 16.4 0.1 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG05657.1 - 1.4e-06 28.8 2.9 0.014 15.8 0.1 3.1 2 1 1 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAG05657.1 - 2.2e-06 27.7 0.4 0.079 13.1 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG05657.1 - 8.7e-05 22.5 0.1 0.05 13.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OAG05657.1 - 0.00026 20.7 0.2 1.4 8.7 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG05657.1 - 0.0012 19.3 0.2 0.63 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 OAG05657.1 - 0.013 15.6 1.4 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 OAG05657.1 - 0.016 15.0 1.0 10 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 OAG05657.1 - 0.017 15.2 1.1 2.3 8.3 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 OAG05657.1 - 0.023 14.4 0.8 1.7 8.4 0.0 3.2 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 OAG05657.1 - 0.041 14.1 0.8 11 6.2 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 OAG05657.1 - 0.088 12.1 0.0 5.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Curto_V3 PF07436.11 OAG05657.1 - 0.25 11.7 1.0 14 6.1 0.0 2.8 2 0 0 2 2 2 0 Curtovirus V3 protein AAA_22 PF13401.6 OAG05657.1 - 0.81 10.0 3.8 17 5.7 0.1 3.2 2 1 0 2 2 2 0 AAA domain DUF2841 PF11001.8 OAG05658.1 - 1.5e-16 60.6 0.3 2.5e-16 59.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Med3 PF11593.8 OAG05658.1 - 0.45 9.7 4.9 0.81 8.8 4.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SAC3_GANP PF03399.16 OAG05659.1 - 3.6e-59 200.6 3.2 3.6e-59 200.6 3.2 1.8 2 0 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAG05659.1 - 0.012 15.5 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family ThiF PF00899.21 OAG05663.1 - 4.9e-32 111.2 0.0 7.5e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family PIG-X PF08320.12 OAG05664.1 - 4.1e-60 203.3 0.0 6.4e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 ComX PF05952.12 OAG05664.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX SARAF PF06682.12 OAG05665.1 - 2.5e-100 336.4 5.9 2.9e-100 336.1 5.9 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF3437 PF11919.8 OAG05666.1 - 0.096 12.6 0.3 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) F-box-like PF12937.7 OAG05667.1 - 2.7e-11 43.2 1.1 5.5e-11 42.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG05667.1 - 1.2e-06 28.2 0.8 0.00025 20.8 0.1 2.8 2 0 0 2 2 2 2 F-box domain Cu_amine_oxid PF01179.20 OAG05668.1 - 1.9e-166 554.1 0.2 2.3e-166 553.8 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAG05668.1 - 4.8e-05 23.7 0.0 9.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Methyltransf_31 PF13847.6 OAG05670.1 - 6.4e-24 84.5 0.0 9.3e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05670.1 - 9.2e-18 64.8 0.0 1.9e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG05670.1 - 1.4e-17 63.9 0.0 2.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG05670.1 - 1.4e-15 57.7 0.0 3.7e-15 56.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG05670.1 - 4.6e-14 52.9 0.0 9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG05670.1 - 2e-11 44.0 0.0 3.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GFA PF04828.14 OAG05670.1 - 8.5e-11 42.1 0.4 1.8e-10 41.0 0.4 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FtsJ PF01728.19 OAG05670.1 - 5.4e-07 29.9 0.0 5.8e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 OAG05670.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAG05670.1 - 0.00091 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG05670.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 OAG05670.1 - 0.044 14.8 0.0 0.097 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 OAG05670.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 OAG05670.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Spc7 PF08317.11 OAG05671.1 - 0.02 13.8 4.2 0.035 13.0 4.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2524 PF10732.9 OAG05671.1 - 0.051 13.9 5.9 0.41 11.0 4.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) MscS_porin PF12795.7 OAG05671.1 - 0.18 11.3 15.1 0.82 9.2 15.2 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3584 PF12128.8 OAG05671.1 - 0.24 8.9 10.7 0.34 8.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1635 PF07795.11 OAG05671.1 - 0.43 10.4 4.5 1.1 9.1 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Csm1_N PF18504.1 OAG05671.1 - 0.49 10.8 4.5 2.4 8.5 1.9 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Med2 PF11214.8 OAG05671.1 - 2.2 8.5 5.2 15 5.8 5.2 2.2 1 1 0 1 1 1 0 Mediator complex subunit 2 DER1 PF04511.15 OAG05673.1 - 3.1e-31 108.8 6.7 3.6e-31 108.6 6.7 1.0 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 OAG05673.1 - 0.096 13.3 1.4 0.16 12.5 0.2 2.0 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) RNA_pol_I_A49 PF06870.12 OAG05675.1 - 1.1e-91 307.6 1.9 1.3e-91 307.3 1.9 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor TetR_C_11 PF16859.5 OAG05675.1 - 1.9 8.8 4.8 16 5.9 4.8 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Promethin PF16015.5 OAG05676.1 - 1.9e-32 111.4 15.5 2.6e-32 110.9 15.5 1.2 1 0 0 1 1 1 1 Promethin DUF1700 PF08006.11 OAG05676.1 - 3.5 7.1 9.6 7.2 6.1 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Macro PF01661.21 OAG05677.1 - 5.1e-40 136.2 0.0 7.6e-22 77.6 0.0 2.7 2 0 0 2 2 2 2 Macro domain RE_Bsp6I PF09504.10 OAG05677.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Bsp6I restriction endonuclease zf-HC2 PF13490.6 OAG05677.1 - 0.87 9.9 2.8 3.8 7.8 0.1 3.3 3 0 0 3 3 3 0 Putative zinc-finger zf-H2C2_2 PF13465.6 OAG05677.1 - 1 9.9 5.5 3 8.4 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain HeLo PF14479.6 OAG05678.1 - 0.025 14.4 1.1 0.053 13.3 1.1 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation Dor1 PF04124.12 OAG05678.1 - 0.068 11.9 1.1 5.1 5.7 0.0 2.7 3 0 0 3 3 3 0 Dor1-like family SMI1_KNR4 PF09346.10 OAG05679.1 - 1.4e-31 109.6 0.0 4e-31 108.2 0.0 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) HSF_DNA-bind PF00447.17 OAG05680.1 - 7.1e-28 97.1 0.4 1.4e-27 96.1 0.4 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 OAG05680.1 - 0.083 13.4 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Ets-domain Diphtheria_C PF02763.14 OAG05680.1 - 0.097 12.3 0.0 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Diphtheria toxin, C domain Spc7 PF08317.11 OAG05680.1 - 0.16 10.8 2.0 0.76 8.6 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2968 PF11180.8 OAG05680.1 - 4.1 7.0 11.4 1.2 8.7 2.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) SNF2_N PF00176.23 OAG05683.1 - 1.3e-65 221.5 1.7 3e-65 220.3 1.7 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 OAG05683.1 - 1.3e-48 164.8 22.0 1.3e-48 164.8 22.0 4.2 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 OAG05683.1 - 4.2e-19 68.9 0.0 1.6e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG05683.1 - 2.1e-08 34.4 0.0 2.1e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAG05683.1 - 0.0028 16.9 0.0 0.0028 16.9 0.0 3.2 4 0 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OAG05683.1 - 0.0033 17.2 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Brix PF04427.18 OAG05684.1 - 1.5e-40 139.4 0.1 1.9e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 Brix domain F-box PF00646.33 OAG05686.1 - 0.018 14.9 0.1 0.046 13.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 OAG05686.1 - 0.068 13.1 0.3 0.34 10.8 0.2 2.2 2 0 0 2 2 2 0 F-box-like TPT PF03151.16 OAG05687.1 - 5.9e-11 42.2 10.5 7.4e-11 41.9 10.5 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAG05687.1 - 3.8e-07 30.3 6.9 3.8e-07 30.3 6.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family ARD PF03079.14 OAG05688.1 - 1.2e-45 155.5 0.1 1.6e-45 155.1 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 OAG05688.1 - 1.6e-10 40.5 0.3 2.9e-10 39.7 0.3 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG05688.1 - 5.9e-07 29.5 0.1 7.9e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAG05688.1 - 0.00014 21.5 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG05688.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 OAG05688.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Cupin DMSP_lyase PF16867.5 OAG05688.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Dimethlysulfonioproprionate lyase Thioredoxin PF00085.20 OAG05690.1 - 0.001 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin EamA PF00892.20 OAG05691.1 - 0.00045 20.4 31.0 0.0005 20.3 8.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Peptidase_A24 PF01478.18 OAG05691.1 - 8.6 6.8 16.0 0.5 10.8 2.0 3.6 2 2 1 3 3 3 0 Type IV leader peptidase family adh_short PF00106.25 OAG05693.1 - 1.1e-24 87.1 0.0 6.2e-24 84.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG05693.1 - 3.1e-20 72.7 0.0 6.6e-20 71.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG05693.1 - 0.00013 21.9 0.6 0.00025 21.0 0.2 1.7 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG05693.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MARVEL PF01284.23 OAG05695.1 - 0.08 13.0 3.1 0.7 9.9 3.1 2.1 1 1 0 1 1 1 0 Membrane-associating domain Peptidase_C78 PF07910.13 OAG05697.1 - 9.1e-64 214.8 0.0 1.2e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf_UBZ PF18439.1 OAG05697.1 - 2.9e-08 33.2 0.5 1.4e-07 30.9 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-RAG1 PF10426.9 OAG05697.1 - 0.025 14.7 0.2 0.065 13.4 0.2 1.7 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain Myosin_head PF00063.21 OAG05698.1 - 3.4e-260 865.0 0.1 3.4e-260 865.0 0.1 1.5 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.19 OAG05698.1 - 2e-27 95.5 2.0 9.9e-27 93.3 2.0 2.3 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 OAG05698.1 - 1.3e-15 55.7 30.5 6.3e-05 22.4 0.3 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif Spc7 PF08317.11 OAG05698.1 - 3.8e-05 22.7 19.6 8.3e-05 21.6 19.6 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein Myosin_N PF02736.19 OAG05698.1 - 0.00047 19.9 0.9 0.0013 18.5 0.9 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 OAG05698.1 - 0.0018 17.7 19.4 0.0018 17.7 19.4 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_22 PF13401.6 OAG05698.1 - 0.0028 17.9 2.7 0.0099 16.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain TACC_C PF05010.14 OAG05698.1 - 0.0041 17.0 22.3 0.012 15.4 22.3 1.8 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF812 PF05667.11 OAG05698.1 - 0.013 14.4 21.7 0.027 13.3 21.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_16 PF13191.6 OAG05698.1 - 0.016 15.6 0.4 0.082 13.3 0.0 2.5 2 0 0 2 2 1 0 AAA ATPase domain T2SSE PF00437.20 OAG05698.1 - 0.036 13.1 0.0 0.084 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein CALCOCO1 PF07888.11 OAG05698.1 - 0.041 12.8 23.1 0.077 11.9 23.1 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Flp_N PF03930.14 OAG05698.1 - 0.083 12.9 1.1 0.22 11.5 0.2 2.2 2 0 0 2 2 1 0 Recombinase Flp protein N-terminus KASH_CCD PF14662.6 OAG05698.1 - 0.11 12.4 33.2 2.7 7.8 11.2 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 OAG05698.1 - 0.15 10.2 24.0 0.32 9.1 24.0 1.5 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Phage_GP20 PF06810.11 OAG05698.1 - 0.24 11.2 21.4 0.018 14.8 4.6 3.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 HsbA PF12296.8 OAG05698.1 - 0.28 11.6 5.3 0.31 11.5 0.6 3.0 2 1 1 3 3 2 0 Hydrophobic surface binding protein A CENP-F_leu_zip PF10473.9 OAG05698.1 - 0.48 10.5 35.7 0.087 12.9 8.7 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dna2 PF08696.11 OAG05698.1 - 0.49 10.2 4.1 1.9 8.3 4.1 2.1 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF1664 PF07889.12 OAG05698.1 - 1.3 9.1 13.1 0.29 11.2 0.6 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 OAG05698.1 - 2.2 8.2 13.3 7.4 6.5 4.0 3.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Tropomyosin PF00261.20 OAG05698.1 - 2.2 7.6 27.0 0.99 8.7 11.4 2.5 1 1 1 2 2 2 0 Tropomyosin YscO PF07321.12 OAG05698.1 - 2.2 8.2 29.2 0.54 10.2 12.5 3.4 3 0 0 3 3 3 0 Type III secretion protein YscO ATG16 PF08614.11 OAG05698.1 - 2.5 8.3 32.3 29 4.8 9.5 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lectin_N PF03954.14 OAG05698.1 - 2.5 7.9 11.4 0.33 10.7 1.3 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Jnk-SapK_ap_N PF09744.9 OAG05698.1 - 2.9 8.1 32.4 0.76 10.0 10.2 2.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 PI3K_P85_iSH2 PF16454.5 OAG05698.1 - 3.9 7.1 27.5 0.47 10.0 22.2 2.2 2 0 0 2 2 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TSC22 PF01166.18 OAG05698.1 - 5.4 7.4 15.3 2.5 8.5 1.0 4.4 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF3450 PF11932.8 OAG05698.1 - 7.3 5.8 28.8 6.2 6.1 13.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 OAG05698.1 - 7.4 6.7 31.2 4.5 7.4 6.7 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein 2-Hacid_dh_C PF02826.19 OAG05699.1 - 1.9e-52 177.2 0.0 3.2e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG05699.1 - 2.1e-36 124.5 0.1 2.9e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 OAG05699.1 - 0.00015 21.9 0.1 0.0004 20.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 OAG05699.1 - 0.00016 21.9 0.2 0.00046 20.4 0.2 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 OAG05699.1 - 0.00061 19.5 0.7 0.0029 17.3 0.1 2.3 2 0 0 2 2 2 1 ACT domain IlvN PF07991.12 OAG05699.1 - 0.026 14.1 0.5 0.16 11.6 0.1 2.3 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain G6PD_C PF02781.16 OAG05700.1 - 6.4e-114 380.0 0.0 1.1e-113 379.3 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OAG05700.1 - 1.1e-60 205.2 0.0 2.2e-60 204.3 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 OAG05700.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Ribosomal_L35Ae PF01247.18 OAG05701.1 - 3.1e-44 149.0 0.2 3.5e-44 148.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OAG05701.1 - 4.4e-06 26.8 0.0 0.045 14.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain MFS_2 PF13347.6 OAG05702.1 - 9.1e-15 54.1 4.3 9.1e-15 54.1 4.3 2.3 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 OAG05702.1 - 2e-06 26.9 0.0 5.7e-06 25.4 0.0 1.9 1 1 1 2 2 2 1 MFS_1 like family BT1 PF03092.16 OAG05702.1 - 0.00041 18.7 4.0 0.0008 17.8 3.5 1.6 2 0 0 2 2 2 1 BT1 family PUCC PF03209.15 OAG05702.1 - 0.0013 17.8 1.8 0.0031 16.6 1.8 1.6 1 0 0 1 1 1 1 PUCC protein NAP PF00956.18 OAG05703.1 - 1.6e-99 332.5 10.5 1.6e-99 332.5 10.5 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 PF11705.8 OAG05703.1 - 8.2 6.6 29.2 2.4 8.3 18.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 AAA_18 PF13238.6 OAG05705.1 - 1.9e-28 99.6 0.1 3e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAG05705.1 - 3.9e-09 37.1 0.1 2.1e-08 34.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG05705.1 - 2e-07 31.3 0.0 1.1e-05 25.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 OAG05705.1 - 3.6e-06 27.2 0.1 0.00096 19.3 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase dNK PF01712.19 OAG05705.1 - 8.1e-06 25.8 0.6 0.016 15.1 0.1 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_28 PF13521.6 OAG05705.1 - 8.8e-06 26.1 0.0 2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG05705.1 - 0.00014 22.3 0.0 0.00033 21.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 OAG05705.1 - 0.00019 21.0 0.0 0.00041 19.9 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NTPase_1 PF03266.15 OAG05705.1 - 0.00021 21.3 0.2 0.00036 20.5 0.0 1.5 2 0 0 2 2 1 1 NTPase Hydin_ADK PF17213.3 OAG05705.1 - 0.0014 18.9 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain SKI PF01202.22 OAG05705.1 - 0.0016 18.6 0.1 0.038 14.1 0.1 2.2 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 OAG05705.1 - 0.0022 18.3 0.0 0.0059 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG05705.1 - 0.003 18.0 0.0 0.0058 17.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.17 OAG05705.1 - 0.0033 17.1 0.0 2.6 7.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Cytidylate_kin2 PF13189.6 OAG05705.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_24 PF13479.6 OAG05705.1 - 0.0053 16.5 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain UCMA PF17085.5 OAG05705.1 - 0.006 16.6 0.2 0.009 16.0 0.2 1.2 1 0 0 1 1 1 1 Unique cartilage matrix associated protein AAA_14 PF13173.6 OAG05705.1 - 0.0064 16.5 0.0 0.024 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG05705.1 - 0.019 15.4 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 OAG05705.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 OAG05705.1 - 0.032 13.2 0.2 0.072 12.1 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 OAG05705.1 - 0.036 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OAG05705.1 - 0.038 13.7 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 OAG05705.1 - 0.039 13.7 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 OAG05705.1 - 0.048 14.0 0.3 0.088 13.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 OAG05705.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 OAG05705.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OAG05705.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 OAG05705.1 - 0.12 11.7 0.4 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 OAG05705.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 OAG05705.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.5 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 OAG05705.1 - 0.33 10.6 1.7 2.1 8.0 0.6 2.2 1 1 1 2 2 2 0 AAA domain Ham1p_like PF01725.16 OAG05706.1 - 5.2e-59 199.3 0.0 5.9e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family GST_N_3 PF13417.6 OAG05708.1 - 4.2e-13 49.5 0.0 6.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG05708.1 - 2.6e-12 46.9 0.0 5.5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG05708.1 - 2.2e-08 34.2 0.0 4.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG05708.1 - 6.4e-07 29.6 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG05708.1 - 1e-06 28.7 0.1 2.3e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG05708.1 - 4.1e-05 23.7 0.0 7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG05708.1 - 0.006 17.1 0.0 0.1 13.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NACHT PF05729.12 OAG05709.1 - 3.1e-09 36.9 0.0 7.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG05709.1 - 4.4e-05 23.9 3.9 0.00029 21.3 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 OAG05709.1 - 0.0016 18.4 0.0 0.013 15.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 OAG05709.1 - 0.0066 15.7 0.0 2.9 7.1 0.0 2.7 1 1 1 2 2 2 2 KAP family P-loop domain DUF2075 PF09848.9 OAG05709.1 - 0.018 14.3 0.5 0.076 12.2 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) CaMBD PF02888.16 OAG05709.1 - 0.058 13.6 0.2 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 Calmodulin binding domain AAA_30 PF13604.6 OAG05709.1 - 0.1 12.3 0.1 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAG05709.1 - 0.18 12.1 0.0 0.84 10.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAG05709.1 - 0.71 9.2 3.1 9 5.6 0.1 2.8 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 OAG05709.1 - 1.1 9.0 3.6 1.3 8.8 0.3 2.4 2 1 1 3 3 3 0 AAA domain SNF2_N PF00176.23 OAG05710.1 - 5.7e-66 222.6 0.1 8.1e-66 222.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG05710.1 - 2.3e-13 50.5 0.0 1.9e-12 47.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG05710.1 - 2.1e-08 34.4 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OAG05710.1 - 0.00091 18.9 0.0 0.016 14.9 0.0 2.4 1 1 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 OAG05710.1 - 0.0041 16.9 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAG05710.1 - 0.05 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zinc_ribbon_10 PF10058.9 OAG05710.1 - 0.47 10.2 3.2 2.4 7.9 3.2 2.2 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 OAG05710.1 - 1.1 9.4 5.0 3.5 7.7 5.0 1.9 1 0 0 1 1 1 0 Double zinc ribbon zf-Tim10_DDP PF02953.15 OAG05711.1 - 1.2e-21 76.1 0.1 1.6e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF228 PF02989.14 OAG05711.1 - 0.024 14.4 0.1 0.03 14.2 0.1 1.1 1 0 0 1 1 1 0 Lyme disease proteins of unknown function PDT PF00800.18 OAG05712.1 - 7.8e-57 192.0 0.0 1.4e-56 191.2 0.0 1.4 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 OAG05712.1 - 0.00066 19.4 0.0 0.006 16.3 0.0 2.2 2 0 0 2 2 2 1 ACT domain eRF1_2 PF03464.15 OAG05713.1 - 3.4e-47 160.1 0.1 5.4e-47 159.4 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAG05713.1 - 9.4e-39 132.4 0.4 1.9e-38 131.4 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OAG05713.1 - 1e-20 74.0 0.0 1.6e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 OAG05713.1 - 1.7e-09 38.0 0.0 3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 OAG05713.1 - 1.9e-08 34.7 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Rad50_zn_hook PF04423.14 OAG05713.1 - 0.16 11.9 1.0 20 5.1 0.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif Aa_trans PF01490.18 OAG05714.1 - 2.2e-62 211.1 30.3 2.6e-62 210.8 30.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 OAG05714.1 - 0.012 16.0 3.1 0.012 16.0 3.1 3.0 3 1 0 3 3 3 0 MerC mercury resistance protein adh_short_C2 PF13561.6 OAG05715.1 - 1.1e-60 205.1 0.0 1.3e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG05715.1 - 7.3e-48 162.6 0.0 9.6e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG05715.1 - 3.6e-11 43.3 0.2 1.6e-10 41.2 0.2 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG05715.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.19 OAG05716.1 - 4e-59 200.4 0.0 6.9e-59 199.6 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG05716.1 - 1.3e-27 97.1 0.0 2.1e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG05716.1 - 9.9e-05 22.5 0.1 0.00025 21.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG05716.1 - 0.00077 18.6 0.0 0.069 12.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG05716.1 - 0.0011 18.6 0.1 0.0085 15.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG05716.1 - 0.006 15.9 0.1 0.089 12.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MtrD PF04207.12 OAG05716.1 - 0.059 13.1 0.2 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D TrkA_N PF02254.18 OAG05716.1 - 0.068 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAG05716.1 - 0.082 12.1 0.0 1.1 8.4 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG05716.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Torus PF16131.5 OAG05717.1 - 1e-43 148.4 0.9 2e-43 147.5 0.0 1.9 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 OAG05717.1 - 7.6e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAG05717.1 - 0.00086 19.3 0.2 0.00086 19.3 0.2 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 OAG05717.1 - 0.0022 17.9 0.3 0.0038 17.1 0.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 OAG05717.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Chromate_transp PF02417.15 OAG05719.1 - 1.2e-58 197.7 39.5 1e-33 116.7 15.3 2.4 3 0 0 3 3 3 2 Chromate transporter DUF4387 PF14330.6 OAG05721.1 - 7.4e-33 113.2 0.0 1.5e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 OAG05721.1 - 9.4e-12 44.3 0.0 1.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 OAG05722.1 - 4.4e-06 25.9 0.1 7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.28 OAG05723.1 - 4.9e-13 49.8 0.1 1.2e-11 45.3 0.0 2.8 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 OAG05723.1 - 1.3e-07 31.1 4.5 2.2e-05 24.2 0.7 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG05723.1 - 7.3e-06 25.8 3.4 8e-06 25.7 0.3 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG05723.1 - 7.9e-06 25.5 1.7 0.00052 19.7 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG05723.1 - 4.9e-05 23.9 4.3 0.055 14.1 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG05723.1 - 0.00024 21.6 1.0 0.0022 18.6 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG05723.1 - 0.0065 16.7 2.0 0.018 15.3 0.7 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG05723.1 - 0.024 14.8 0.7 9.9 6.4 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG05723.1 - 0.066 13.7 5.7 0.27 11.8 0.9 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG05723.1 - 0.071 13.2 0.5 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 OAG05723.1 - 0.098 12.7 0.6 0.68 10.1 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat SAF PF08666.12 OAG05723.1 - 0.12 13.0 0.0 1.3 9.7 0.0 2.6 2 0 0 2 2 2 0 SAF domain RTA1 PF04479.13 OAG05724.1 - 5.2e-70 235.3 7.8 7.8e-70 234.7 7.8 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4231 PF14015.6 OAG05724.1 - 0.036 14.5 1.1 0.22 12.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4668 PF15701.5 OAG05724.1 - 0.47 10.3 3.6 0.15 11.9 0.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4668) Acetyltransf_1 PF00583.25 OAG05725.1 - 9.5e-11 42.0 0.0 1.9e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG05725.1 - 9.8e-07 29.1 0.1 2.2e-06 28.0 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG05725.1 - 6e-06 26.2 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG05725.1 - 0.031 14.3 0.1 0.079 13.0 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ThuA PF06283.11 OAG05727.1 - 3.3e-57 194.1 0.0 3.7e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.6 OAG05727.1 - 0.005 16.3 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) ABC1 PF03109.16 OAG05729.1 - 4.5e-35 120.4 0.0 1.1e-34 119.1 0.0 1.7 1 0 0 1 1 1 1 ABC1 family CN_hydrolase PF00795.22 OAG05730.1 - 1.4e-15 57.3 0.0 9e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase FOLN PF09289.10 OAG05730.1 - 0.076 13.2 0.3 0.14 12.3 0.3 1.5 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Ribosomal_L39 PF00832.20 OAG05731.1 - 1.9e-21 75.4 9.4 2.1e-21 75.2 9.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein DNA_RNApol_7kD PF03604.13 OAG05732.1 - 2.4e-10 39.9 1.9 2.4e-10 39.9 1.9 1.6 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit zf-C3HC PF07967.13 OAG05732.1 - 0.004 17.2 0.4 0.0057 16.7 0.4 1.3 1 0 0 1 1 1 1 C3HC zinc finger-like zf-ribbon_3 PF13248.6 OAG05732.1 - 0.083 12.3 0.3 0.21 11.1 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Nop14 PF04147.12 OAG05732.1 - 0.2 9.8 9.6 0.2 9.8 9.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAG05732.1 - 1.1 7.5 7.4 1.1 7.5 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAG05732.1 - 1.5 8.2 10.9 1.7 8.0 10.9 1.2 1 0 0 1 1 1 0 SDA1 PH PF00169.29 OAG05737.1 - 0.00089 19.7 0.1 0.0027 18.2 0.1 1.9 1 1 0 1 1 1 1 PH domain LRR_1 PF00560.33 OAG05737.1 - 0.0022 18.3 4.5 47 5.1 0.0 6.8 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 OAG05737.1 - 0.015 15.3 10.1 1.1 9.5 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich repeat Pet127 PF08634.10 OAG05738.1 - 2.4e-116 388.0 0.4 3.1e-116 387.6 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 LXG PF04740.12 OAG05739.1 - 0.12 12.1 1.1 0.26 11.0 0.2 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4298 PF14131.6 OAG05739.1 - 0.54 10.3 3.2 3.8 7.5 1.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) CdvA PF18822.1 OAG05739.1 - 1.5 8.7 5.4 3.7 7.4 2.8 2.7 2 1 0 2 2 2 0 CdvA-like coiled-coil domain FadA PF09403.10 OAG05739.1 - 5.5 7.5 8.5 1.5e+02 2.9 5.7 3.2 2 1 0 2 2 2 0 Adhesion protein FadA APH PF01636.23 OAG05740.1 - 3.8e-14 53.2 0.2 1.3e-13 51.5 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG05740.1 - 3.6e-06 26.5 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OAG05740.1 - 2e-05 23.7 0.0 2.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAG05740.1 - 0.0088 15.6 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DIOX_N PF14226.6 OAG05741.1 - 3.2e-28 98.8 0.0 5.5e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG05741.1 - 1.9e-19 70.0 0.0 3.7e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG05742.1 - 1.8e-30 106.0 14.0 1.8e-30 106.0 14.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily P66_CC PF16563.5 OAG05742.1 - 0.029 14.0 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Phage_holin_5_2 PF16079.5 OAG05742.1 - 1.6 9.1 11.0 0.078 13.3 2.9 2.9 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V P5-ATPase PF12409.8 OAG05743.1 - 4.1e-40 136.8 0.1 9e-40 135.7 0.1 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 OAG05743.1 - 3.1e-32 111.6 0.2 9.2e-32 110.0 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG05743.1 - 9.8e-18 65.2 0.0 4.8e-09 36.8 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 OAG05743.1 - 5e-05 23.1 7.1 5e-05 23.1 7.1 2.7 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OAG05743.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG05743.1 - 0.0019 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG05743.1 - 0.22 11.2 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DnaJ_C PF01556.18 OAG05745.1 - 1.7e-34 119.0 0.7 2.3e-34 118.6 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG05745.1 - 5e-29 100.2 2.1 9.2e-29 99.4 2.1 1.5 1 0 0 1 1 1 1 DnaJ domain DKCLD PF08068.12 OAG05746.1 - 2.1e-32 110.9 0.1 1.4e-30 105.1 0.1 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 OAG05746.1 - 9.9e-23 80.1 0.9 1.9e-22 79.2 0.9 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 OAG05746.1 - 3.4e-22 79.4 5.2 2.4e-20 73.4 0.2 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 OAG05746.1 - 4.3e-20 71.4 0.7 9.2e-20 70.4 0.7 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 OAG05746.1 - 0.021 15.1 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain SH3_11 PF18103.1 OAG05747.1 - 0.025 14.7 0.7 0.043 14.0 0.3 1.7 1 1 1 2 2 2 0 Retroviral integrase C-terminal SH3 domain UFD1 PF03152.14 OAG05749.1 - 6.5e-73 243.9 0.0 8.2e-73 243.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 GYF PF02213.16 OAG05750.1 - 2.2e-10 40.0 0.2 4.6e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OAG05750.1 - 0.067 13.0 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 GYF domain 2 R3H PF01424.22 OAG05752.1 - 7.9e-11 41.8 0.1 1.6e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 OAG05752.1 - 1.5e-05 24.7 0.1 3.3e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.24 OAG05753.1 - 4.3e-16 59.5 0.0 5.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OAG05753.1 - 1e-12 47.5 0.1 2e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OAG05753.1 - 0.00073 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Striatin PF08232.12 OAG05754.1 - 7.6e-46 156.5 7.6 1.8e-45 155.3 7.6 1.6 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 OAG05754.1 - 5.5e-24 84.0 21.3 0.00017 22.3 0.3 8.6 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG05754.1 - 0.00012 22.3 0.0 4.5 7.6 0.1 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain KLRAQ PF10205.9 OAG05754.1 - 0.054 13.7 3.4 0.11 12.8 3.4 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein PXA PF02194.15 OAG05754.1 - 0.06 13.3 0.8 0.1 12.6 0.8 1.2 1 0 0 1 1 1 0 PXA domain DivIVA PF05103.13 OAG05754.1 - 1.4 9.1 7.9 2.8 8.1 7.9 1.5 1 0 0 1 1 1 0 DivIVA protein Mucin-like PF16058.5 OAG05757.1 - 0.0054 16.8 18.4 0.0054 16.8 18.4 3.5 1 1 1 3 3 3 2 Mucin-like Peptidase_C97 PF05903.14 OAG05758.1 - 0.039 13.8 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 PPPDE putative peptidase domain CPSF100_C PF13299.6 OAG05758.1 - 0.41 10.8 4.1 0.97 9.6 0.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ribosomal_S3Ae PF01015.18 OAG05760.1 - 1.1e-87 292.9 4.7 1.3e-87 292.6 4.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 OAG05760.1 - 0.017 15.7 0.1 0.56 10.8 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 OAG05760.1 - 0.039 14.0 0.1 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO GTP_CH_N PF12471.8 OAG05763.1 - 5.9e-92 306.7 0.0 9.1e-92 306.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAG05763.1 - 3e-17 62.7 0.0 5.3e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II Laminin_I PF06008.14 OAG05763.1 - 0.03 14.0 1.8 0.045 13.4 1.8 1.1 1 0 0 1 1 1 0 Laminin Domain I MT0933_antitox PF14013.6 OAG05763.1 - 0.31 11.4 1.7 1.1 9.6 0.5 2.4 2 0 0 2 2 2 0 MT0933-like antitoxin protein Elf1 PF05129.13 OAG05764.1 - 3.8e-31 107.0 1.2 4.8e-31 106.7 1.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 OAG05764.1 - 0.0044 17.0 1.6 0.23 11.5 0.2 2.3 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger PHD_4 PF16866.5 OAG05764.1 - 0.0047 17.0 0.3 0.0092 16.0 0.3 1.5 1 0 0 1 1 1 1 PHD-finger Zn-ribbon_8 PF09723.10 OAG05764.1 - 0.052 13.7 0.8 0.12 12.5 0.8 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Vps36-NZF-N PF16988.5 OAG05764.1 - 0.062 12.7 1.0 0.14 11.5 1.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_Tnp_IS1595 PF12760.7 OAG05764.1 - 0.082 12.9 0.3 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain MRNIP PF15749.5 OAG05764.1 - 0.15 12.8 2.5 0.3 11.8 2.2 1.8 1 1 1 2 2 2 0 MRN-interacting protein zf-C2H2_4 PF13894.6 OAG05764.1 - 0.2 12.6 3.0 0.74 10.8 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LITAF-like PF10601.9 OAG05764.1 - 0.25 11.6 3.9 5.2 7.4 0.5 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-C2H2_2 PF12756.7 OAG05764.1 - 0.5 10.7 2.8 8.8 6.7 0.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OAG05764.1 - 0.52 10.9 0.3 0.52 10.9 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type UPRTase PF14681.6 OAG05765.1 - 3.6e-80 268.3 0.0 4.6e-80 268.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAG05765.1 - 0.00023 20.7 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain WAPL PF07814.13 OAG05766.1 - 2.8e-43 148.1 0.1 4.3e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.22 OAG05767.1 - 8.1e-46 155.6 0.3 9.2e-46 155.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG05767.1 - 9.9e-16 58.1 0.0 1.4e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG05767.1 - 6.9e-09 35.4 0.0 7.4e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG05767.1 - 1.9e-05 24.2 0.1 4.5e-05 22.9 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OAG05767.1 - 8.6e-05 22.2 0.1 0.00096 18.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG05767.1 - 0.00012 22.0 0.4 0.017 15.0 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG05767.1 - 0.00013 22.0 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG05767.1 - 0.0029 17.1 0.0 0.018 14.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 OAG05767.1 - 0.014 15.4 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain tRNA-synt_2b PF00587.25 OAG05768.1 - 1.8e-32 112.8 0.0 2.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAG05768.1 - 1.8e-16 60.3 7.6 4.2e-16 59.1 7.6 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain PIN_12 PF16289.5 OAG05768.1 - 0.052 14.0 4.4 0.073 13.6 3.4 1.7 2 0 0 2 2 2 0 PIN domain TssO PF17561.2 OAG05768.1 - 0.24 11.5 3.7 0.51 10.4 3.7 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO SPT16 PF08644.11 OAG05768.1 - 0.87 9.8 4.0 1.3 9.2 2.7 1.9 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF4515 PF14988.6 OAG05768.1 - 2.6 7.9 12.0 0.87 9.4 9.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) HATPase_c PF02518.26 OAG05769.1 - 1.6e-23 83.3 0.0 4.6e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG05769.1 - 5.2e-17 62.0 1.3 7.4e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAG05769.1 - 1.3e-10 41.2 0.2 3.8e-10 39.7 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 OAG05769.1 - 3.3e-06 27.3 0.0 1.1e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OAG05769.1 - 6.1e-05 23.2 0.1 0.00024 21.3 0.1 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAG05769.1 - 0.0076 16.5 0.0 0.024 14.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain F-box-like PF12937.7 OAG05770.1 - 5e-06 26.3 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG05770.1 - 0.00067 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 OAG05771.1 - 1.2e-37 129.7 30.6 1.2e-37 129.7 30.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG05771.1 - 2.2e-08 33.4 11.0 2.2e-08 33.4 11.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG05771.1 - 0.0007 18.1 1.8 0.0012 17.4 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG05771.1 - 0.013 13.8 3.8 0.044 12.1 2.5 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 OAG05772.1 - 7e-08 32.5 6.0 1.3e-07 31.6 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3322 PF11795.8 OAG05772.1 - 0.068 13.2 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Fungal_trans PF04082.18 OAG05773.1 - 1.1e-10 41.0 0.6 1.1e-10 41.0 0.6 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain PglL_A PF15864.5 OAG05775.1 - 0.14 11.9 1.5 0.34 10.7 1.5 1.6 1 0 0 1 1 1 0 Protein glycosylation ligase DPBB_1 PF03330.18 OAG05776.1 - 7.1e-07 29.4 4.7 1.9e-06 28.1 2.3 2.8 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 OAG05776.1 - 1.2e-05 25.1 0.6 3.4e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Barwin family Pollen_allerg_1 PF01357.21 OAG05776.1 - 0.00047 20.1 1.9 0.00047 20.1 1.9 1.5 2 0 0 2 2 2 1 Pollen allergen BNR PF02012.20 OAG05776.1 - 0.0083 16.0 0.9 0.052 13.6 0.1 2.7 2 0 0 2 2 2 1 BNR/Asp-box repeat Fungal_trans_2 PF11951.8 OAG05777.1 - 3.1e-23 82.2 2.5 7.3e-23 81.0 2.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain PYRIN PF02758.16 OAG05777.1 - 0.054 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain MFS_1 PF07690.16 OAG05779.1 - 2.9e-41 141.6 28.1 7.6e-40 136.9 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG05779.1 - 5.7e-09 35.4 0.1 5.7e-09 35.4 0.1 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG05779.1 - 0.0004 19.3 1.7 0.0078 15.1 1.6 2.8 1 1 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 OAG05779.1 - 0.27 10.0 8.0 1.3 7.7 8.0 2.2 1 1 0 1 1 1 0 LacY proton/sugar symporter Pkinase PF00069.25 OAG05780.1 - 2.1e-10 40.4 0.0 3.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAG05780.1 - 0.0019 18.2 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OAG05780.1 - 0.028 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAG05780.1 - 0.039 12.9 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OAG05780.1 - 0.065 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG05780.1 - 0.082 12.2 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like HATPase_c PF02518.26 OAG05781.1 - 2e-20 73.4 0.0 4.2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG05781.1 - 2.8e-17 62.9 0.0 7.5e-17 61.5 0.0 1.8 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG05781.1 - 6.1e-07 29.4 0.2 1.7e-06 27.9 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 OAG05781.1 - 0.0011 19.1 0.0 0.04 14.2 0.0 3.2 3 1 0 3 3 3 1 PAS domain PAS_4 PF08448.10 OAG05781.1 - 0.0031 17.7 0.2 0.06 13.6 0.0 3.1 2 1 1 3 3 3 1 PAS fold PAS_8 PF13188.7 OAG05781.1 - 0.0046 16.9 0.0 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 OAG05781.1 - 0.12 12.7 0.1 0.52 10.6 0.1 2.1 1 0 0 1 1 1 0 PAS fold HATPase_c_3 PF13589.6 OAG05781.1 - 0.14 12.0 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.16 OAG05782.1 - 1e-13 51.0 34.9 4.8e-13 48.8 21.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2371 PF10177.9 OAG05782.1 - 0.3 11.2 1.1 5.3 7.2 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) OATP PF03137.20 OAG05782.1 - 3.1 6.0 9.2 0.15 10.3 2.2 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HTH_psq PF05225.16 OAG05784.1 - 0.0042 16.8 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain UPF0561 PF10573.9 OAG05784.1 - 1.1 9.3 11.6 0.22 11.7 7.0 2.1 1 1 0 2 2 2 0 Uncharacterised protein family UPF0561 LIDHydrolase PF10230.9 OAG05785.1 - 1.2e-73 247.9 0.0 1.4e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OAG05785.1 - 5.3e-05 23.9 0.1 7e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 OAG05785.1 - 0.0005 19.6 0.1 0.00073 19.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 OAG05785.1 - 0.0021 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG05785.1 - 0.004 16.4 0.0 0.0076 15.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 OAG05785.1 - 0.0043 16.3 0.0 0.0057 15.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 OAG05785.1 - 0.035 13.2 0.0 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_8 PF06259.12 OAG05785.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase TPR_2 PF07719.17 OAG05786.1 - 1.3e-31 106.1 21.9 0.003 17.6 0.2 13.4 14 0 0 14 14 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 OAG05786.1 - 7.7e-26 88.8 20.9 4.1e-05 23.2 0.4 11.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 OAG05786.1 - 1.6e-19 68.4 18.2 0.0027 17.8 0.1 12.6 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG05786.1 - 1.1e-14 53.9 24.5 1.1 10.3 0.0 14.6 13 4 3 16 16 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG05786.1 - 7.6e-14 52.0 24.5 0.0026 18.2 0.0 10.4 10 4 2 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAG05786.1 - 4.7e-13 49.5 12.1 0.038 14.7 0.0 9.8 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG05786.1 - 1e-12 48.1 34.1 0.027 14.7 0.0 11.7 10 3 3 13 13 13 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAG05786.1 - 2.3e-10 40.0 23.2 0.24 11.1 0.6 9.7 9 1 1 10 10 10 5 TPR repeat TPR_7 PF13176.6 OAG05786.1 - 3.4e-10 39.2 11.6 0.054 13.5 0.0 10.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG05786.1 - 2.9e-09 36.6 10.5 0.55 10.7 0.1 10.5 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG05786.1 - 3e-06 27.5 36.8 0.12 13.1 0.0 12.7 18 0 0 18 18 12 2 Tetratricopeptide repeat DUF2225 PF09986.9 OAG05786.1 - 0.0093 15.7 10.1 0.07 12.8 0.3 4.4 2 2 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 OAG05786.1 - 0.046 13.6 33.3 0.061 13.2 1.1 9.0 12 0 0 12 12 10 0 Tetratricopeptide repeat TOM20_plant PF06552.12 OAG05786.1 - 0.73 9.6 6.0 2 8.2 0.1 3.6 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 PPR PF01535.20 OAG05786.1 - 1.4 9.3 6.3 18 5.9 0.0 5.1 5 0 0 5 5 5 0 PPR repeat Fis1_TPR_C PF14853.6 OAG05786.1 - 1.9 8.6 12.1 7.6 6.7 0.2 5.6 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 OAG05786.1 - 2.3 8.5 18.7 2.9 8.2 0.1 7.0 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 OAG05786.1 - 2.6 8.2 17.2 2.7 8.1 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Sec8_exocyst PF04048.14 OAG05787.1 - 8.4e-48 161.9 4.6 3.4e-47 159.9 4.6 2.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 OAG05787.1 - 4e-09 36.2 7.0 1.3e-08 34.5 7.0 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 OAG05787.1 - 1e-05 24.4 4.5 2.3e-05 23.2 4.5 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF745 PF05335.13 OAG05787.1 - 0.25 11.0 1.3 0.88 9.3 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF745) IZUMO PF15005.6 OAG05787.1 - 0.28 11.7 2.0 1.4 9.4 1.1 2.6 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Vps51 PF08700.11 OAG05787.1 - 0.96 9.6 4.5 1.9 8.6 0.5 3.2 3 0 0 3 3 3 0 Vps51/Vps67 Glyco_hyd_65N_2 PF14498.6 OAG05788.1 - 8.3e-58 196.0 4.2 1.2e-57 195.4 4.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain AA_permease_2 PF13520.6 OAG05789.1 - 1e-85 288.2 38.1 1.3e-85 287.9 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease PsbN PF02468.15 OAG05789.1 - 0.98 9.3 6.1 0.37 10.7 1.7 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) ADH_N PF08240.12 OAG05791.1 - 6.2e-09 35.7 0.1 8.5e-08 32.1 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG05791.1 - 2.6e-07 31.8 0.0 8.1e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG05791.1 - 0.00012 22.1 0.0 0.00049 20.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hydro_11 PF00457.17 OAG05793.1 - 5e-44 150.1 11.3 6.8e-44 149.6 11.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Oxidored_molyb PF00174.19 OAG05794.1 - 1.6e-51 174.4 0.0 3e-51 173.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG05794.1 - 1.8e-28 99.3 5.0 1.7e-27 96.2 5.0 2.3 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 OAG05794.1 - 2e-22 79.9 0.0 1.6e-21 77.0 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG05794.1 - 2.6e-17 63.0 0.0 3.5e-15 56.2 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 OAG05794.1 - 3.7e-13 49.4 0.2 8.5e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAG05794.1 - 0.004 17.3 0.1 1.5 8.9 0.0 2.7 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF4637 PF15470.6 OAG05794.1 - 0.025 14.3 0.4 0.069 12.9 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) HET PF06985.11 OAG05795.1 - 3.2e-19 69.7 0.1 3.6e-19 69.6 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_1N PF02870.15 OAG05798.1 - 0.095 13.5 0.1 0.26 12.1 0.1 1.7 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain F-box-like PF12937.7 OAG05799.1 - 0.02 14.8 0.1 0.066 13.1 0.0 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 OAG05799.1 - 0.032 14.1 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 OAG05799.1 - 0.11 12.4 0.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 F-box p450 PF00067.22 OAG05802.1 - 1.1e-60 205.7 0.0 1.3e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SelB-wing_2 PF09106.11 OAG05802.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix IFRD PF05004.13 OAG05802.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) AhpC-TSA_2 PF13911.6 OAG05803.1 - 9e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 OAG05803.1 - 3.5e-08 33.4 0.0 4.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG05803.1 - 0.00031 20.5 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 OAG05803.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like FRG1 PF06229.12 OAG05804.1 - 2e-49 167.9 0.0 3.4e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 OAG05804.1 - 0.047 13.9 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 Fascin domain DIOX_N PF14226.6 OAG05805.1 - 0.00084 20.1 0.0 0.0018 19.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG05805.1 - 0.0035 17.8 0.0 0.0079 16.7 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.18 OAG05806.1 - 1.4e-29 103.0 29.7 1.6e-29 102.8 29.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Polysacc_deac_1 PF01522.21 OAG05807.1 - 3.5e-17 62.4 0.0 7.1e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG05807.1 - 1.9e-05 24.4 0.2 7.8e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) ADH_N PF08240.12 OAG05808.1 - 1.1e-23 83.2 1.1 1.8e-23 82.5 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG05808.1 - 5e-17 62.1 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG05808.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG05808.1 - 0.07 12.4 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amidase PF01425.21 OAG05809.1 - 6e-93 312.3 0.1 7.2e-93 312.0 0.1 1.0 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 OAG05810.1 - 2.8e-58 197.3 0.1 3.5e-58 196.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG05810.1 - 3.6e-43 147.3 0.1 4.4e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG05810.1 - 3.4e-08 33.6 0.1 5.4e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 KR domain ThiF PF00899.21 OAG05810.1 - 0.0023 17.3 3.7 0.053 12.9 1.3 2.7 2 1 2 4 4 4 2 ThiF family Fungal_trans PF04082.18 OAG05811.1 - 1e-19 70.6 0.7 1.5e-19 70.0 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rpb2_4 PF04566.13 OAG05812.1 - 0.041 14.2 0.1 0.25 11.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 COQ9 PF08511.11 OAG05812.1 - 0.085 12.6 0.2 0.26 11.1 0.2 1.8 1 0 0 1 1 1 0 COQ9 DUF5379 PF17350.2 OAG05812.1 - 1.8 8.9 6.2 14 6.1 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5379) F-box PF00646.33 OAG05813.1 - 3.1e-07 30.1 0.6 1.5e-06 27.9 0.0 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OAG05813.1 - 1.9e-06 27.6 0.1 8.2e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like TPR_2 PF07719.17 OAG05813.1 - 4.4e-06 26.4 3.0 0.0029 17.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG05813.1 - 4e-05 23.3 4.3 0.015 15.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 OAG05813.1 - 0.0082 16.1 0.8 3.5 7.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG05813.1 - 0.025 14.8 4.6 0.72 10.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG05813.1 - 0.066 13.9 3.5 0.62 10.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.6 OAG05813.1 - 0.097 12.4 0.9 3 7.7 0.0 3.8 3 1 0 3 3 3 0 Leucine rich repeat TPR_12 PF13424.6 OAG05813.1 - 0.33 11.3 1.4 7.8 6.9 0.4 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 OAG05813.1 - 2.5 8.7 5.6 12 6.5 0.1 4.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) NPR2 PF06218.11 OAG05814.1 - 3.2e-162 540.3 0.0 4.2e-162 539.9 0.0 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.13 OAG05814.1 - 0.0065 15.3 0.6 0.37 9.5 0.0 3.2 2 1 1 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 A_deaminase PF00962.22 OAG05815.1 - 5.5e-21 75.2 0.0 1.1e-20 74.2 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase ATG2_CAD PF13329.6 OAG05816.1 - 5.3e-41 139.9 0.0 1.4e-40 138.6 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 OAG05816.1 - 2.6e-26 91.8 0.5 1.7e-25 89.1 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Fungal_trans_2 PF11951.8 OAG05817.1 - 1.7e-15 56.7 0.8 2.3e-15 56.3 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG05817.1 - 1.9e-06 27.9 7.4 1.9e-06 27.9 7.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylsulfotran_2 PF14269.6 OAG05818.1 - 1.1e-62 212.1 0.7 1.5e-62 211.6 0.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG05818.1 - 3.6e-20 72.2 0.1 1e-18 67.4 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Cupin_2 PF07883.11 OAG05819.1 - 2.9e-21 75.0 0.7 2.4e-18 65.6 0.2 2.5 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG05819.1 - 0.00023 20.8 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAG05819.1 - 0.00036 20.4 0.1 0.00076 19.4 0.1 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain DMSP_lyase PF16867.5 OAG05819.1 - 0.022 14.4 0.1 0.053 13.2 0.1 1.6 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Auxin_BP PF02041.16 OAG05819.1 - 0.039 13.6 0.0 7.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Auxin binding protein ECH_1 PF00378.20 OAG05820.1 - 9.2e-25 87.4 0.0 1.2e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG05820.1 - 2e-09 37.4 0.0 3.5e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_hydro_16 PF00722.21 OAG05821.1 - 1.3e-43 148.5 4.4 2.2e-43 147.7 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Trp_oprn_chp PF09534.10 OAG05821.1 - 0.0093 15.8 0.6 0.0093 15.8 0.6 1.7 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Protocadherin PF08374.11 OAG05821.1 - 0.015 15.3 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 OAG05821.1 - 0.093 13.6 1.4 0.12 13.3 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 OAG05821.1 - 0.23 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TFB6 PF17110.5 OAG05822.1 - 8.5e-47 159.1 0.8 3.6e-46 157.0 0.0 2.1 2 0 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH Glyco_hydro_35 PF01301.19 OAG05826.1 - 3.7e-91 306.1 0.4 5e-91 305.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 OAG05826.1 - 1e-62 211.2 0.3 1.8e-62 210.4 0.3 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 OAG05826.1 - 1.8e-54 183.2 5.0 9.6e-31 106.7 0.1 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 OAG05826.1 - 1.7e-17 62.7 0.1 3.7e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 OAG05826.1 - 0.0047 16.3 0.2 0.017 14.5 0.1 1.9 1 1 1 2 2 2 1 Beta-galactosidase DUF5496 PF17600.2 OAG05826.1 - 0.1 12.6 0.3 0.76 9.9 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5496) RPS31 PF17067.5 OAG05826.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S31e CN_hydrolase PF00795.22 OAG05827.1 - 2.9e-55 187.4 0.0 3.3e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zinc_ribbon_15 PF17032.5 OAG05828.1 - 0.00027 21.6 1.2 0.00041 21.0 1.2 1.3 1 0 0 1 1 1 1 zinc-ribbon family Dynein_light PF01221.18 OAG05829.1 - 2.7e-40 136.5 2.0 3.1e-40 136.4 2.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.22 OAG05830.1 - 2e-73 242.2 1.2 2e-17 62.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG05830.1 - 4.7e-16 58.4 0.0 1.7e-06 27.8 0.0 5.2 5 0 0 5 5 5 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG05830.1 - 9.9e-11 41.5 0.1 0.015 15.3 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAG05830.1 - 1.1e-07 31.8 0.1 0.69 10.1 0.0 4.5 4 0 0 4 4 4 2 RNA recognition motif PHM7_cyt PF14703.6 OAG05830.1 - 1.8e-05 25.1 5.7 13 5.9 0.0 6.5 7 0 0 7 7 7 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 OAG05830.1 - 0.0003 20.8 0.1 3.7 7.6 0.0 4.0 4 0 0 4 4 4 2 RNA binding motif Smg4_UPF3 PF03467.15 OAG05830.1 - 0.00039 20.5 2.8 0.28 11.2 0.0 3.7 3 0 0 3 3 3 2 Smg-4/UPF3 family Limkain-b1 PF11608.8 OAG05830.1 - 0.00062 19.8 0.0 0.68 10.0 0.0 3.7 3 0 0 3 3 3 1 Limkain b1 RL PF17797.1 OAG05830.1 - 0.011 15.6 0.0 0.3 11.1 0.0 3.2 3 0 0 3 3 3 0 RL domain Glyco_hydro_65m PF03632.15 OAG05830.1 - 0.085 11.7 0.3 1.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 65 central catalytic domain EspF PF04806.12 OAG05831.1 - 0.12 12.8 1.4 0.31 11.5 1.4 1.8 1 0 0 1 1 1 0 EspF protein repeat dsrm PF00035.26 OAG05832.1 - 1e-05 26.2 0.0 6.1 7.6 0.0 3.8 3 0 0 3 3 3 3 Double-stranded RNA binding motif HMG_box PF00505.19 OAG05833.1 - 1.8e-08 34.7 1.0 1.8e-08 34.7 1.0 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box Amidohydro_1 PF01979.20 OAG05834.1 - 7.4e-77 259.0 1.9 1e-76 258.5 1.2 1.5 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 OAG05834.1 - 4.8e-56 188.3 1.9 1e-55 187.2 1.9 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 OAG05834.1 - 8.8e-41 137.9 0.5 2.5e-40 136.4 0.1 1.9 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 OAG05834.1 - 1.2e-38 131.3 0.1 2.9e-38 130.2 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 OAG05834.1 - 2.6e-09 37.1 0.5 1.2e-07 31.6 0.0 2.1 1 1 0 2 2 2 1 Amidohydrolase family Corona_nucleoca PF00937.18 OAG05835.1 - 0.091 11.8 2.7 5.1 6.0 0.1 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein TFIIA PF03153.13 OAG05837.1 - 0.0087 16.1 8.6 0.011 15.8 8.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1681 PF07933.14 OAG05837.1 - 0.083 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) HMG14_17 PF01101.18 OAG05837.1 - 0.27 12.2 4.4 1.5 9.9 1.2 2.5 2 0 0 2 2 2 0 HMG14 and HMG17 Stm1_N PF09598.10 OAG05837.1 - 0.37 11.7 12.1 3.1 8.7 0.0 3.3 4 1 0 4 4 4 0 Stm1 RskA PF10099.9 OAG05838.1 - 6.2 7.1 11.9 3.4 7.9 7.7 2.6 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Het-C PF07217.11 OAG05839.1 - 4e-246 818.0 0.0 5.1e-246 817.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C MMM1 PF10296.9 OAG05840.1 - 2e-05 23.8 0.0 6.7e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Catalase PF00199.19 OAG05842.1 - 7.2e-170 565.2 0.1 9.7e-170 564.8 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG05842.1 - 1.8e-17 63.2 0.2 4.2e-17 62.1 0.2 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 OAG05842.1 - 5.8e-11 42.3 0.2 1.3e-10 41.1 0.2 1.7 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 OAG05842.1 - 1e-08 35.1 0.0 2.8e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family Corona_3 PF04694.12 OAG05842.1 - 0.051 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Coronavirus ORF3 protein APH PF01636.23 OAG05845.1 - 2.3e-11 44.1 0.5 0.00018 21.5 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family TrkH PF02386.16 OAG05846.1 - 1e-78 265.1 8.1 1.7e-75 254.4 2.1 2.1 2 0 0 2 2 2 2 Cation transport protein Senescence PF06911.12 OAG05847.1 - 7.2e-48 163.3 8.3 1e-47 162.8 8.3 1.2 1 0 0 1 1 1 1 Senescence-associated protein DIOX_N PF14226.6 OAG05849.1 - 7.1e-26 91.3 0.0 2.4e-24 86.3 0.0 2.4 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG05849.1 - 1e-12 48.4 0.0 1.8e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily bZIP_2 PF07716.15 OAG05850.1 - 0.00025 21.0 10.9 0.041 14.0 2.7 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 OAG05850.1 - 0.00029 20.9 13.3 0.00046 20.2 4.5 2.2 1 1 1 2 2 2 2 bZIP transcription factor YabA PF06156.13 OAG05850.1 - 0.0007 20.2 0.1 0.0013 19.3 0.1 1.4 1 0 0 1 1 1 1 Initiation control protein YabA TSC22 PF01166.18 OAG05850.1 - 0.00098 19.4 1.1 0.0069 16.7 0.3 2.2 2 0 0 2 2 2 1 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 OAG05850.1 - 0.028 14.7 4.0 0.052 13.8 4.0 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Shugoshin_N PF07558.11 OAG05850.1 - 0.14 12.0 1.5 0.29 11.0 1.5 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Glyco_hydro_1 PF00232.18 OAG05852.1 - 7.5e-147 489.4 0.2 9.1e-147 489.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 OAG05852.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1479 PF07350.12 OAG05853.1 - 2.8e-166 553.4 0.0 3.3e-166 553.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 OAG05853.1 - 0.04 14.2 0.5 2.4 8.4 0.3 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Sulfatase PF00884.23 OAG05856.1 - 3.2e-57 194.3 0.3 4.1e-57 193.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAG05856.1 - 0.00027 20.7 2.0 0.0012 18.5 2.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 OAG05856.1 - 0.0029 17.8 0.0 0.0067 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 OAG05856.1 - 0.0039 15.9 0.0 0.0071 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Fungal_trans PF04082.18 OAG05858.1 - 1.3e-12 47.3 0.6 3.9e-12 45.8 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG05858.1 - 2e-08 34.2 3.6 1.8e-05 24.9 0.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAG05858.1 - 6e-06 26.1 1.9 2.5e-05 24.1 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG05858.1 - 2.5e-05 24.7 3.1 0.0013 19.4 0.2 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 OAG05858.1 - 0.0054 17.1 0.6 0.11 13.0 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OAG05858.1 - 0.0095 15.8 3.0 0.016 15.1 0.1 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 OAG05858.1 - 0.023 14.5 2.4 0.031 14.0 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 OAG05858.1 - 0.03 14.6 0.2 0.7 10.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OAG05858.1 - 0.13 12.8 10.2 4.5 7.9 0.2 4.1 3 1 0 3 3 3 0 Zinc-finger double domain p450 PF00067.22 OAG05859.1 - 3.1e-18 65.8 0.0 6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG05860.1 - 4.5e-38 131.1 47.2 5.5e-31 107.8 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 OAG05860.1 - 9.9 6.2 20.5 0.14 12.2 8.2 3.1 1 1 2 3 3 3 0 Membrane-associating domain DUF4246 PF14033.6 OAG05861.1 - 4.7e-172 573.2 0.8 5.6e-172 572.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 OAG05861.1 - 0.072 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase GMC_oxred_N PF00732.19 OAG05862.1 - 9.9e-34 117.1 0.1 1.5e-31 109.9 0.1 2.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG05862.1 - 1.3e-27 97.1 0.0 1.7e-26 93.5 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAG05862.1 - 0.00032 20.0 0.0 0.00063 19.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG05862.1 - 0.0017 18.5 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG05862.1 - 0.0093 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG05862.1 - 0.028 13.7 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MoeA_N PF03453.17 OAG05863.1 - 1.6e-31 109.2 1.0 2.4e-31 108.7 1.0 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 OAG05863.1 - 5.7e-10 39.0 0.1 1.8e-09 37.4 0.1 1.8 1 1 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 OAG05863.1 - 0.048 13.8 0.0 0.5 10.6 0.0 2.8 3 0 0 3 3 3 0 MoeA C-terminal region (domain IV) Glyco_hydro_61 PF03443.14 OAG05864.1 - 2.9e-49 167.8 0.8 3.3e-49 167.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAG05864.1 - 3.9e-12 45.9 6.2 3.9e-12 45.9 6.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Zn_clus PF00172.18 OAG05865.1 - 6.8e-06 26.1 13.3 1.2e-05 25.4 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG05865.1 - 0.00057 18.8 1.3 0.00057 18.8 1.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 OAG05866.1 - 2.5e-07 30.3 0.1 5.5e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG05866.1 - 0.0034 17.3 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Glyco_hydro_3_C PF01915.22 OAG05867.1 - 4.1e-37 128.1 0.0 7.3e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG05867.1 - 2.6e-35 122.4 0.0 3.8e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG05867.1 - 2.5e-06 27.5 0.0 6.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM-like PF14683.6 OAG05868.1 - 1.1e-35 122.9 0.2 2.5e-35 121.8 0.2 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 OAG05868.1 - 1.6e-14 53.5 1.6 4.5e-14 52.0 1.6 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OAG05868.1 - 5e-09 36.3 1.5 1.2e-08 35.1 0.5 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Inhibitor_I42 PF09394.10 OAG05868.1 - 0.017 15.5 0.6 0.073 13.5 0.1 2.4 2 0 0 2 2 2 0 Chagasin family peptidase inhibitor I42 DUF4198 PF10670.9 OAG05868.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) CarbopepD_reg_2 PF13715.6 OAG05868.1 - 0.077 13.0 2.1 0.77 9.8 0.6 3.1 2 1 0 2 2 2 0 CarboxypepD_reg-like domain DUF1961 PF09224.11 OAG05869.1 - 4.2e-99 330.2 0.0 4.9e-99 330.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) DUF1080 PF06439.11 OAG05869.1 - 0.0032 17.6 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) CHAP PF05257.16 OAG05870.1 - 2.9e-14 53.4 4.5 4.4e-14 52.8 4.5 1.2 1 0 0 1 1 1 1 CHAP domain Dyp_perox PF04261.12 OAG05871.1 - 2.7e-87 292.8 0.0 3.1e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family SKG6 PF08693.10 OAG05872.1 - 0.00052 19.4 0.5 0.00052 19.4 0.5 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAG05872.1 - 0.0076 16.4 2.0 0.018 15.1 2.0 1.6 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 OAG05872.1 - 0.012 15.5 0.9 0.018 14.9 0.2 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Flavodoxin_5 PF12724.7 OAG05873.1 - 1.3e-24 87.1 0.0 1.6e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 OAG05873.1 - 0.00033 20.9 0.0 0.00056 20.1 0.0 1.6 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_3 PF12641.7 OAG05873.1 - 0.037 13.7 0.0 0.074 12.7 0.0 1.5 2 0 0 2 2 2 0 Flavodoxin domain Transferase PF02458.15 OAG05875.1 - 0.00013 20.8 0.0 0.00021 20.1 0.0 1.3 1 0 0 1 1 1 1 Transferase family Terpene_synth_C PF03936.16 OAG05876.1 - 0.00052 19.4 0.0 0.00087 18.7 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 OAG05876.1 - 0.057 12.3 0.1 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) p450 PF00067.22 OAG05877.1 - 2.1e-67 227.8 0.0 2.8e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peripla_BP_7 PF18610.1 OAG05877.1 - 0.003 17.7 0.0 0.0093 16.1 0.0 1.8 1 0 0 1 1 1 1 Periplasmic binding protein domain NmrA PF05368.13 OAG05878.1 - 1e-21 77.6 0.0 1.2e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG05878.1 - 1.8e-15 57.3 0.9 3e-15 56.6 0.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG05878.1 - 4.5e-05 23.0 0.5 0.00021 20.8 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG05878.1 - 0.0027 16.9 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 OAG05878.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG05878.1 - 0.079 13.4 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Response_reg PF00072.24 OAG05879.1 - 2.6e-23 82.3 1.7 1.8e-22 79.6 1.7 2.3 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG05879.1 - 5.4e-21 75.2 0.0 9.7e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG05879.1 - 7.4e-08 32.3 0.4 4.4e-07 29.9 0.1 2.5 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 OAG05879.1 - 2.6e-07 31.0 0.0 2e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_4 PF08448.10 OAG05879.1 - 5.9e-05 23.3 0.0 0.0002 21.6 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OAG05879.1 - 0.00015 21.7 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 OAG05879.1 - 0.00073 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OAG05879.1 - 0.0023 18.2 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.6 OAG05879.1 - 0.0035 17.7 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 GAF domain DUF1828 PF08861.10 OAG05879.1 - 0.0052 17.0 0.0 0.023 15.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function DUF1828 PAS PF00989.25 OAG05879.1 - 0.0082 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 OAG05879.1 - 0.049 14.3 0.0 0.094 13.4 0.0 1.5 1 0 0 1 1 1 0 GAF domain ketoacyl-synt PF00109.26 OAG05883.1 - 3.1e-70 236.6 0.0 5.2e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 OAG05883.1 - 1.2e-62 211.8 0.0 2.1e-62 211.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAG05883.1 - 4.1e-51 173.4 0.8 1.8e-50 171.4 0.1 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 OAG05883.1 - 1.1e-45 156.5 0.1 1.9e-45 155.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG05883.1 - 7.8e-38 129.1 0.1 1.7e-37 128.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAG05883.1 - 6.3e-16 58.9 0.0 2.2e-15 57.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG05883.1 - 1.4e-15 57.7 0.1 6.6e-13 49.1 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 OAG05883.1 - 3.8e-14 52.8 0.0 1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG05883.1 - 2e-12 47.1 0.0 5.9e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 OAG05883.1 - 5.5e-12 45.8 0.0 1.9e-11 44.0 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAG05883.1 - 1.4e-11 45.0 0.0 1.4e-09 38.6 0.0 3.7 3 0 0 3 3 3 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 OAG05883.1 - 6.4e-11 43.4 0.0 2e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG05883.1 - 1.1e-09 38.0 2.7 1.5e-07 31.1 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_11 PF08241.12 OAG05883.1 - 1.4e-09 38.4 0.0 1.9e-08 34.8 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 OAG05883.1 - 4.7e-06 26.9 0.0 1.4e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 OAG05883.1 - 6.5e-05 22.6 0.1 0.00016 21.3 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Catalase-rel PF06628.12 OAG05883.1 - 7.1e-05 22.9 0.8 0.0002 21.5 0.1 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive Thiolase_N PF00108.23 OAG05883.1 - 0.0002 20.8 0.1 0.0004 19.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 OAG05883.1 - 0.0003 20.2 0.0 0.00075 18.9 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OAG05883.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 OAG05883.1 - 0.0024 17.6 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase ADH_N PF08240.12 OAG05883.1 - 0.027 14.4 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF2196 PF09962.9 OAG05883.1 - 0.093 12.7 0.2 23 5.1 0.0 3.6 4 0 0 4 4 3 0 Uncharacterized conserved protein (DUF2196) AlaDh_PNT_C PF01262.21 OAG05883.1 - 0.13 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_2 PF00891.18 OAG05884.1 - 1.5e-26 93.0 0.0 3.1e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAG05884.1 - 1.1e-07 32.4 0.0 2.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG05884.1 - 3.3e-05 24.5 0.0 8.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG05884.1 - 0.00039 20.0 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OAG05884.1 - 0.00099 19.7 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG05884.1 - 0.0045 16.8 0.0 0.012 15.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAG05884.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG05884.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAG05884.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 OAG05884.1 - 0.071 12.2 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Rrf2 PF02082.20 OAG05884.1 - 0.083 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_15 PF12324.8 OAG05884.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Methyltransf_32 PF13679.6 OAG05884.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4719 PF15843.5 OAG05885.1 - 0.0056 16.8 0.2 0.0074 16.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4719) adh_short PF00106.25 OAG05886.1 - 1e-12 47.9 0.0 3.6e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG05886.1 - 4.5e-06 26.7 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG05886.1 - 0.0087 15.6 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_4 PF01565.23 OAG05887.1 - 9.1e-22 77.3 0.0 1.6e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG05887.1 - 0.15 12.2 0.0 0.51 10.5 0.0 1.9 1 0 0 1 1 1 0 Berberine and berberine like p450 PF00067.22 OAG05888.1 - 1.8e-48 165.4 0.0 1.4e-46 159.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 EthD PF07110.11 OAG05889.1 - 5.6e-21 75.5 0.0 7e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG05889.1 - 0.00025 21.5 0.0 0.00037 20.9 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Abhydrolase_1 PF00561.20 OAG05890.1 - 3.8e-15 56.2 0.0 6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG05890.1 - 1.5e-09 38.8 0.0 1.9e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OAG05890.1 - 0.063 12.3 0.0 0.18 10.8 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase Tannase PF07519.11 OAG05891.1 - 2e-115 386.4 3.4 2.4e-115 386.1 3.4 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 OAG05891.1 - 0.00048 19.5 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG05891.1 - 0.015 14.9 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold 14-3-3 PF00244.20 OAG05892.1 - 3.3e-106 353.8 5.6 3.8e-106 353.6 5.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 OAG05892.1 - 0.0067 16.7 1.4 0.66 10.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TerB PF05099.13 OAG05892.1 - 0.02 14.8 1.2 0.042 13.8 0.3 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TerB Orbi_VP5 PF00901.17 OAG05892.1 - 0.14 10.5 2.8 0.23 9.8 2.8 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 IATP PF04568.12 OAG05893.1 - 9.9e-22 77.2 1.4 1.4e-21 76.7 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Herpes_UL14 PF03580.14 OAG05893.1 - 0.007 16.6 1.1 0.0097 16.2 0.3 1.6 2 0 0 2 2 2 1 Herpesvirus UL14-like protein F-box-like PF12937.7 OAG05894.1 - 5.1e-12 45.5 1.2 9.7e-12 44.6 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG05894.1 - 6.3e-07 29.1 1.2 1.4e-06 28.0 1.2 1.6 1 0 0 1 1 1 1 F-box domain DLH PF01738.18 OAG05894.1 - 0.022 14.3 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family SNF2_N PF00176.23 OAG05895.1 - 4.8e-63 213.0 1.6 8.9e-63 212.1 0.1 2.1 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG05895.1 - 4.1e-15 56.1 0.0 7.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG05895.1 - 8.9e-10 38.8 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 OAG05895.1 - 5.9e-09 35.7 4.5 1.3e-08 34.6 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG05895.1 - 6.6e-07 29.3 6.0 1.5e-06 28.1 6.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG05895.1 - 2.7e-06 27.6 7.8 7.6e-06 26.2 7.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG05895.1 - 7.2e-06 25.7 9.4 3.5e-05 23.5 9.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG05895.1 - 1.6e-05 24.7 9.1 3.3e-05 23.7 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG05895.1 - 4.6e-05 23.3 6.8 0.00012 22.0 6.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG05895.1 - 0.00019 21.2 6.7 0.00077 19.3 6.7 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 SPT6_acidic PF14632.6 OAG05895.1 - 0.0059 17.2 11.6 0.0059 17.2 11.6 2.0 2 0 0 2 2 1 1 Acidic N-terminal SPT6 HDA2-3 PF11496.8 OAG05895.1 - 0.0062 15.7 0.1 0.015 14.5 0.1 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-C3HC4_4 PF15227.6 OAG05895.1 - 0.022 14.9 6.9 0.058 13.6 6.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAG05895.1 - 0.14 12.0 6.0 0.48 10.3 6.1 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain SDA1 PF05285.12 OAG05895.1 - 0.26 10.7 10.3 0.046 13.1 6.6 1.5 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 OAG05895.1 - 2 6.6 7.4 3.5 5.8 7.4 1.3 1 0 0 1 1 1 0 CDC45-like protein HET PF06985.11 OAG05897.1 - 1.9e-23 83.4 0.0 3.5e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3328 PF11807.8 OAG05898.1 - 8.7e-14 51.8 0.5 9.9e-14 51.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAG05899.1 - 1.1e-25 90.7 0.8 1.4e-25 90.3 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3889 PF13028.6 OAG05900.1 - 0.0011 18.8 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3889) DUF3920 PF13058.6 OAG05900.1 - 0.23 11.7 2.4 8.6 6.6 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3920) HAMP PF00672.25 OAG05901.1 - 3.6e-35 120.1 22.2 1.5e-07 31.7 0.1 8.2 7 2 1 8 8 8 6 HAMP domain HATPase_c PF02518.26 OAG05901.1 - 3.1e-30 105.0 0.3 1.4e-29 102.9 0.3 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG05901.1 - 3.3e-28 98.1 0.1 2.4e-27 95.3 0.1 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAG05901.1 - 1e-16 60.7 0.5 1e-16 60.7 0.5 4.0 6 0 0 6 6 3 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 OAG05901.1 - 8.5e-11 42.1 12.1 1.2 9.5 0.1 7.3 5 2 1 7 7 7 4 Syntaxin-like protein DUF4279 PF14106.6 OAG05901.1 - 3.3e-05 24.0 0.4 30 4.8 0.0 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4279) Laminin_II PF06009.12 OAG05901.1 - 3.3e-05 23.9 34.4 0.46 10.5 0.8 6.8 7 0 0 7 7 7 4 Laminin Domain II DUF948 PF06103.11 OAG05901.1 - 0.0021 18.3 52.1 0.015 15.6 1.0 9.8 3 2 3 6 6 6 2 Bacterial protein of unknown function (DUF948) AdHead_fibreRBD PF16812.5 OAG05901.1 - 0.082 12.7 0.1 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 C-terminal head domain of the fowl adenovirus type 1 long fibre DUF3829 PF12889.7 OAG05901.1 - 0.16 11.4 13.1 1.6 8.1 0.0 5.0 2 2 3 6 6 6 0 Protein of unknown function (DUF3829) REF PF05755.12 OAG05901.1 - 0.23 11.2 10.9 4.5 7.0 0.4 5.2 2 1 3 5 5 5 0 Rubber elongation factor protein (REF) SpoIIID PF12116.8 OAG05901.1 - 0.8 9.8 3.1 17 5.6 0.0 4.0 4 0 0 4 4 3 0 Stage III sporulation protein D Atg14 PF10186.9 OAG05901.1 - 2.9 6.9 5.3 2.4 7.2 1.0 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 OAG05901.1 - 3.8 7.1 23.0 16 5.0 0.7 5.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) GLE1 PF07817.13 OAG05901.1 - 3.8 6.7 19.2 9.9 5.3 0.4 5.5 2 1 4 6 6 6 0 GLE1-like protein DUF4763 PF15960.5 OAG05901.1 - 4.1 6.6 7.6 9.9 5.4 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4763) Fib_alpha PF08702.10 OAG05901.1 - 5.1 7.3 30.7 1.9 8.7 0.2 7.2 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family DUF5102 PF17104.5 OAG05902.1 - 7.9e-106 354.3 1.3 1.3e-105 353.6 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Caskin-Pro-rich PF16907.5 OAG05902.1 - 3 8.4 10.1 0.12 12.9 1.5 2.9 3 0 0 3 3 3 0 Proline rich region of Caskin proteins Nsp1_C PF05064.13 OAG05903.1 - 1.3e-38 131.4 1.6 1.3e-38 131.4 1.6 2.1 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 OAG05903.1 - 2.3e-06 28.3 157.7 3.8e-05 24.5 32.0 6.8 1 1 5 6 6 5 3 Nucleoporin FG repeat region ERM PF00769.19 OAG05903.1 - 0.032 14.0 12.0 0.072 12.9 12.1 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family OmpH PF03938.14 OAG05903.1 - 0.047 14.0 16.3 0.15 12.4 2.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 OAG05903.1 - 0.063 11.9 9.4 0.011 14.4 2.9 1.9 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.11 OAG05903.1 - 0.07 13.3 12.9 0.038 14.2 1.6 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 OAG05903.1 - 0.18 11.9 4.4 0.56 10.2 4.4 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 OAG05903.1 - 0.3 11.2 17.7 1.8 8.7 6.8 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase STAT_alpha PF01017.20 OAG05903.1 - 0.31 10.9 6.1 0.26 11.2 4.3 1.7 1 1 0 1 1 1 0 STAT protein, all-alpha domain TACC_C PF05010.14 OAG05903.1 - 0.53 10.0 12.8 0.57 9.9 8.8 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal EzrA PF06160.12 OAG05903.1 - 0.59 8.2 12.5 0.46 8.6 1.4 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA FliD_C PF07195.12 OAG05903.1 - 0.77 9.1 6.0 0.4 10.0 3.5 1.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF3450 PF11932.8 OAG05903.1 - 0.81 8.9 16.2 0.34 10.2 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 OAG05903.1 - 1.2 9.5 18.1 3.7 8.0 7.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ING PF12998.7 OAG05903.1 - 2.1 9.0 6.9 1.9 9.1 2.8 2.3 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Laminin_II PF06009.12 OAG05903.1 - 2.2 8.3 12.2 2.5 8.1 2.9 2.4 2 1 0 2 2 2 0 Laminin Domain II Sin3_corepress PF08295.12 OAG05903.1 - 2.4 8.3 4.0 0.85 9.7 0.8 1.8 2 0 0 2 2 2 0 Sin3 family co-repressor zf-C4H2 PF10146.9 OAG05903.1 - 3.7 7.8 9.3 25 5.1 9.3 2.4 1 1 0 1 1 1 0 Zinc finger-containing protein RasGAP_C PF03836.15 OAG05903.1 - 3.8 7.7 10.1 1.4 9.0 1.2 2.3 1 1 1 2 2 2 0 RasGAP C-terminus DUF4407 PF14362.6 OAG05903.1 - 6.4 6.0 10.4 13 5.0 10.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 OAG05903.1 - 7.1 7.0 5.9 3.2 8.1 0.9 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 OAG05903.1 - 7.7 5.7 5.9 4.2 6.6 1.0 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Tho2 PF11262.8 OAG05903.1 - 8.2 5.5 9.0 1.3 8.2 1.8 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF3176 PF11374.8 OAG05904.1 - 7.2e-12 45.5 4.2 7.2e-12 45.5 4.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Peptidase_S8 PF00082.22 OAG05905.1 - 1.4e-35 123.0 11.0 3.3e-35 121.8 11.0 1.5 1 1 0 1 1 1 1 Subtilase family CRISPR_assoc PF08798.11 OAG05907.1 - 0.01 16.0 0.4 0.016 15.3 0.4 1.3 1 0 0 1 1 1 1 CRISPR associated protein WD40 PF00400.32 OAG05908.1 - 4.6e-40 134.9 7.4 1.2e-06 29.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG05908.1 - 5.1e-17 62.0 0.1 1.3e-05 25.4 0.0 5.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OAG05908.1 - 0.046 12.0 0.0 0.22 9.8 0.0 2.0 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 OAG05908.1 - 0.19 10.7 0.0 8.2 5.3 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TRAPP PF04051.16 OAG05909.1 - 7.6e-36 123.0 0.0 9.5e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.6 OAG05909.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) NACHT PF05729.12 OAG05911.1 - 6.4e-09 35.9 0.0 1.9e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 OAG05911.1 - 6.9e-07 29.5 0.8 1.9e-06 28.0 0.8 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 OAG05911.1 - 1.9e-06 28.3 0.1 8.3e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG05911.1 - 0.0022 18.2 0.7 0.012 15.9 0.0 2.6 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 OAG05911.1 - 0.0056 17.2 0.2 0.048 14.2 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 OAG05911.1 - 0.014 15.9 0.0 0.047 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG05911.1 - 0.015 15.7 0.0 0.057 13.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OAG05911.1 - 0.021 14.0 0.0 2.8 7.1 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 OAG05911.1 - 0.029 14.5 0.1 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG05911.1 - 0.035 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OAG05911.1 - 0.036 14.5 0.0 0.13 12.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 OAG05911.1 - 0.058 13.0 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OAG05911.1 - 0.08 12.8 0.0 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OAG05911.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 OAG05911.1 - 0.12 12.5 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Glyco_trans_1_4 PF13692.6 OAG05912.1 - 1.4e-10 41.7 0.0 3.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OAG05912.1 - 4e-08 33.0 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 OAG05912.1 - 0.0013 18.5 0.0 0.015 15.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Polysacc_deac_1 PF01522.21 OAG05913.1 - 0.0075 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_114 PF03537.13 OAG05914.1 - 2.6e-81 272.3 0.0 3.1e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 preSET_CXC PF18264.1 OAG05915.1 - 0.23 12.0 7.0 0.93 10.0 7.0 2.0 1 0 0 1 1 1 0 CXC domain Epimerase PF01370.21 OAG05917.1 - 9.5e-36 123.5 0.0 5e-28 98.2 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG05917.1 - 9.3e-34 117.3 0.0 4.2e-26 92.1 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG05917.1 - 4.1e-07 29.4 0.0 1.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 OAG05917.1 - 1.5e-06 27.6 0.0 0.0019 17.4 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG05917.1 - 4.3e-05 22.7 0.0 0.22 10.5 0.0 2.4 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG05917.1 - 0.04 13.4 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Zn_clus PF00172.18 OAG05918.1 - 6.5e-08 32.6 8.4 1.1e-07 31.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG05918.1 - 1.7e-07 30.6 0.1 2.9e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.22 OAG05920.1 - 6.8e-49 165.6 0.0 8.4e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG05920.1 - 4.4e-29 101.1 0.1 9.9e-29 100.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG05920.1 - 3e-10 39.8 0.0 3.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 OAG05920.1 - 0.00054 20.3 0.1 0.003 17.9 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 OAG05920.1 - 0.00062 19.8 0.0 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG05920.1 - 0.0019 17.6 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 OAG05920.1 - 0.024 14.1 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 OAG05920.1 - 0.037 13.5 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 OAG05920.1 - 0.052 12.7 2.5 1.7 7.7 0.2 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 OAG05920.1 - 0.064 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG05920.1 - 0.07 13.1 0.1 0.16 12.0 0.1 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ArgoMid PF16487.5 OAG05920.1 - 0.094 13.0 0.0 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 Mid domain of argonaute AAA_33 PF13671.6 OAG05920.1 - 0.11 12.7 0.5 0.22 11.7 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG05920.1 - 0.11 12.9 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAG05920.1 - 0.12 12.2 0.3 9.3 6.1 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase Nas2_N PF18265.1 OAG05921.1 - 2.3e-31 107.5 0.3 3.3e-31 107.0 0.3 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 OAG05921.1 - 8.7e-10 38.3 0.1 1.8e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OAG05921.1 - 2e-06 28.1 0.0 3.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OAG05921.1 - 8.9e-06 26.0 0.0 2.3e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 OAG05921.1 - 0.00029 21.2 0.0 0.0011 19.3 0.0 1.8 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain Cast PF10174.9 OAG05921.1 - 0.079 11.2 0.0 0.097 10.9 0.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ABC_tran_CTD PF16326.5 OAG05921.1 - 0.25 11.6 1.3 3.4 8.0 0.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain RhoGEF PF00621.20 OAG05922.1 - 4.9e-28 98.6 0.0 9.9e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF2277 PF10041.9 OAG05922.1 - 0.086 13.2 0.0 0.35 11.2 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) SBDS PF01172.18 OAG05923.1 - 3e-27 94.5 0.3 3.6e-27 94.3 0.3 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AAA PF00004.29 OAG05924.1 - 3.7e-20 72.7 0.0 1.4e-19 70.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG05924.1 - 0.0021 18.3 0.3 0.16 12.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 OAG05924.1 - 0.013 15.3 0.7 0.034 13.9 0.0 2.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OAG05924.1 - 0.022 15.1 1.0 0.094 13.1 0.0 2.5 2 2 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OAG05924.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_11 PF13086.6 OAG05924.1 - 0.13 12.0 1.6 0.52 10.0 1.6 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG05924.1 - 0.15 11.9 0.0 2.2 8.2 0.0 2.5 2 1 1 3 3 3 0 NACHT domain AAA_7 PF12775.7 OAG05924.1 - 0.2 11.1 0.0 0.42 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_polI_A34 PF08208.11 OAG05924.1 - 7.7 6.6 10.9 6.2 6.9 9.3 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 HET PF06985.11 OAG05925.1 - 3.8e-11 43.5 0.1 8e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 OAG05926.1 - 2.5e-47 161.5 0.1 2.9e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Esterase_phd PF10503.9 OAG05927.1 - 7.3e-22 77.9 0.6 1.3e-21 77.1 0.4 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG05927.1 - 1.4e-07 31.2 0.3 2e-07 30.7 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG05927.1 - 0.0017 18.0 2.2 0.0037 16.9 1.7 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Eno-Rase_NADH_b PF12242.8 OAG05927.1 - 0.0019 17.9 0.1 0.0035 17.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Esterase PF00756.20 OAG05927.1 - 0.0035 17.0 0.6 0.0058 16.3 0.6 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAG05927.1 - 0.009 15.8 0.1 0.035 13.9 0.1 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OAG05927.1 - 0.011 15.6 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 OAG05927.1 - 0.1 11.7 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) BAAT_C PF08840.11 OAG05927.1 - 0.13 12.2 0.5 0.27 11.1 0.2 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ADH_N PF08240.12 OAG05928.1 - 4.9e-26 90.8 2.8 4.9e-26 90.8 1.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG05928.1 - 9.8e-06 25.6 0.0 0.00099 19.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG05928.1 - 9.9e-05 22.2 0.7 0.00029 20.7 0.7 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated DUF4879 PF16219.5 OAG05928.1 - 0.026 14.7 0.3 0.69 10.1 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4879) FANCL_C PF11793.8 OAG05928.1 - 0.032 14.4 0.5 0.06 13.5 0.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain LINES_C PF14695.6 OAG05931.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Lines C-terminus NB-ARC PF00931.22 OAG05932.1 - 1.6e-05 24.2 0.0 1.8e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAG05932.1 - 0.0026 18.2 1.6 0.029 14.8 1.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsmJ PF04378.13 OAG05932.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ TPR_10 PF13374.6 OAG05933.1 - 2.9e-43 144.6 0.0 7.9e-12 44.7 0.0 4.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG05933.1 - 2.7e-36 123.7 0.1 7.9e-12 45.3 0.0 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAG05933.1 - 1.4e-12 46.7 0.0 0.0011 18.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG05933.1 - 1.7e-07 30.8 0.0 1.4 9.2 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAG05933.1 - 3e-07 30.3 0.0 0.46 11.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG05933.1 - 3.2e-07 30.9 0.0 0.17 12.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG05933.1 - 2.6e-06 27.0 0.0 0.81 9.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.7 OAG05933.1 - 0.00017 21.8 0.0 1.5 9.1 0.0 2.7 1 1 2 3 3 3 2 Tetratrico peptide repeat TPR_8 PF13181.6 OAG05933.1 - 0.00053 20.0 0.0 13 6.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG05933.1 - 0.00069 19.1 1.3 0.0024 17.3 1.2 1.7 1 1 0 1 1 1 1 MalT-like TPR region TPR_4 PF07721.14 OAG05933.1 - 0.00092 19.6 0.0 1.8 9.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG05933.1 - 0.0018 18.7 0.0 3.7 8.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG05933.1 - 0.0054 17.5 0.2 7.5 7.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG05933.1 - 0.01 16.4 0.1 47 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF630 PF04783.12 OAG05933.1 - 0.11 12.6 0.0 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF630) Osmo_CC PF08946.10 OAG05933.1 - 0.15 12.3 1.6 69 3.8 0.1 3.8 4 0 0 4 4 4 0 Osmosensory transporter coiled coil APH PF01636.23 OAG05934.1 - 3.6e-09 36.9 0.0 3.5e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family MSP1_C PF07462.11 OAG05934.1 - 0.034 12.9 0.8 0.048 12.4 0.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Tir_receptor_C PF07489.11 OAG05934.1 - 0.05 13.6 3.9 0.085 12.8 3.9 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DAG_kinase_N PF14513.6 OAG05934.1 - 0.094 12.9 1.4 0.16 12.1 1.4 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF411 PF04214.13 OAG05934.1 - 0.23 11.4 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF SSP160 PF06933.11 OAG05934.1 - 0.8 7.8 6.4 1.1 7.4 6.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TcpS PF17456.2 OAG05935.1 - 0.026 14.6 1.0 0.039 14.0 1.0 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S AAA_23 PF13476.6 OAG05936.1 - 2.1e-29 103.5 0.4 2.1e-29 103.5 0.4 6.8 1 1 1 4 4 2 1 AAA domain SMC_N PF02463.19 OAG05936.1 - 2.8e-08 33.5 33.0 4e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG05936.1 - 2.3e-07 31.0 8.9 0.0025 17.7 0.0 3.8 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAG05936.1 - 7.1e-06 26.2 0.0 2.3e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 OAG05936.1 - 0.00011 22.1 59.3 0.00037 20.3 0.6 4.5 1 1 1 4 4 2 2 AAA ATPase domain CENP-F_leu_zip PF10473.9 OAG05936.1 - 0.0011 19.0 23.0 0.0011 19.0 23.0 7.6 3 3 4 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.6 OAG05936.1 - 0.0038 16.9 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 OAG05936.1 - 0.008 14.9 97.1 0.057 12.1 15.7 5.4 1 1 3 4 4 4 2 AAA domain Lip_prot_lig_C PF10437.9 OAG05936.1 - 0.091 12.8 1.8 20 5.2 0.2 3.3 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus AAA_22 PF13401.6 OAG05936.1 - 0.19 12.0 0.0 0.19 12.0 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 OAG05936.1 - 0.68 10.3 0.0 0.68 10.3 0.0 4.3 3 2 0 3 3 2 0 AAA ATPase domain HHH_8 PF14716.6 OAG05936.1 - 1.3 9.5 7.6 0.91 9.9 1.1 4.3 4 0 0 4 4 4 0 Helix-hairpin-helix domain GATA PF00320.27 OAG05937.1 - 2.2e-16 59.2 6.1 5.4e-16 57.9 6.1 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 OAG05937.1 - 1.5e-12 47.6 0.0 4.4e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAG05937.1 - 3.9e-09 36.5 0.0 8.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAG05937.1 - 1.4e-08 35.0 0.0 3.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 OAG05937.1 - 3.2e-06 27.2 0.0 7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OAG05937.1 - 4.7e-05 23.6 0.0 0.00024 21.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain Zn-ribbon_8 PF09723.10 OAG05937.1 - 0.0064 16.6 0.2 0.013 15.6 0.2 1.5 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 OAG05937.1 - 0.21 11.1 0.6 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 OAG05937.1 - 0.36 10.8 6.3 0.068 13.1 1.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) HPP PF04982.13 OAG05939.1 - 9.2e-40 135.6 4.2 9.2e-40 135.6 4.2 1.6 2 0 0 2 2 2 1 HPP family DUF4064 PF13273.6 OAG05939.1 - 1.1 9.6 10.8 1.3 9.4 3.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) TFCD_C PF12612.8 OAG05940.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Beta-lactamase PF00144.24 OAG05943.1 - 6.1e-36 124.3 0.0 1.4e-35 123.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase FAD_binding_4 PF01565.23 OAG05944.1 - 1.1e-16 60.8 0.4 1.5e-16 60.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 OAG05944.1 - 1.8e-10 41.1 0.9 4.3e-09 36.6 0.9 2.3 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Sugar_tr PF00083.24 OAG05945.1 - 1.4e-84 284.6 24.2 1.6e-84 284.4 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG05945.1 - 2.5e-19 69.4 28.2 2.5e-19 69.4 28.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG05945.1 - 0.00017 20.6 4.2 0.00017 20.6 4.2 1.7 2 0 0 2 2 2 1 MFS_1 like family Fungal_trans PF04082.18 OAG05946.1 - 1.8e-12 46.9 0.1 2.7e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG05947.1 - 3e-11 43.2 13.9 8.4e-08 32.3 6.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG05947.1 - 5.9e-11 42.2 14.0 1.4e-05 25.3 2.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG05947.1 - 1.2e-07 31.9 11.8 0.0019 18.9 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG05947.1 - 0.00066 19.6 1.7 0.00066 19.6 1.7 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG05947.1 - 0.011 15.5 6.4 0.079 12.7 1.1 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 OAG05947.1 - 0.098 12.4 0.4 0.098 12.4 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 OAG05947.1 - 0.29 11.6 8.0 0.19 12.2 4.3 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 OAG05947.1 - 1.4 8.6 6.0 0.84 9.3 0.3 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Glyco_hydro_31 PF01055.26 OAG05948.1 - 1.8e-110 370.2 3.6 2.6e-110 369.7 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG05948.1 - 0.00022 21.5 0.2 0.0014 18.9 0.2 2.4 2 1 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 OAG05948.1 - 0.00082 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Oxidored_molyb PF00174.19 OAG05949.1 - 1.5e-46 158.1 0.0 4.3e-46 156.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG05949.1 - 4.5e-20 72.1 2.5 9.2e-20 71.1 2.5 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Glyco_hydro_127 PF07944.12 OAG05949.1 - 0.053 12.0 0.1 0.077 11.5 0.1 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Abhydrolase_1 PF00561.20 OAG05950.1 - 8e-11 42.1 0.0 3.1e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG05950.1 - 0.00021 20.7 0.0 0.00033 20.0 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAG05950.1 - 0.11 12.3 0.0 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Methyltransf_16 PF10294.9 OAG05951.1 - 5.2e-14 52.3 0.0 8e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OAG05951.1 - 0.00053 19.6 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAG05951.1 - 0.0015 19.2 0.0 0.0027 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG05951.1 - 0.0018 18.9 0.0 0.0044 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG05951.1 - 0.041 13.7 0.0 0.081 12.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain CFEM PF05730.11 OAG05952.1 - 1.4e-12 47.5 6.1 1.4e-12 47.5 6.1 1.9 2 0 0 2 2 2 1 CFEM domain Inhibitor_I9 PF05922.16 OAG05953.1 - 0.00086 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 RIBIOP_C PF04950.12 OAG05954.1 - 7.2e-96 321.0 0.3 7.2e-96 321.0 0.3 1.9 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAG05954.1 - 4.3e-28 97.2 0.0 1.2e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 OAG05954.1 - 9.2e-06 25.3 0.0 0.0019 17.8 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAG05954.1 - 3.9e-05 23.9 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG05954.1 - 0.00032 20.9 0.0 0.001 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAG05954.1 - 0.00038 20.9 0.0 0.00085 19.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG05954.1 - 0.00064 20.1 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAG05954.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OAG05954.1 - 0.0021 18.6 0.0 0.008 16.7 0.0 2.0 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 OAG05954.1 - 0.0059 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 OAG05954.1 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.6 OAG05954.1 - 0.01 16.2 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 OAG05954.1 - 0.02 14.5 0.2 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 OAG05954.1 - 0.022 14.7 0.6 0.17 11.8 0.1 2.6 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 OAG05954.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAG05954.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 OAG05954.1 - 0.034 13.1 0.0 0.085 11.8 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OAG05954.1 - 0.034 14.5 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OAG05954.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG05954.1 - 0.053 14.1 0.2 0.053 14.1 0.2 3.4 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 OAG05954.1 - 0.056 13.3 0.4 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 OAG05954.1 - 0.063 13.3 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OAG05954.1 - 0.1 12.6 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Roc PF08477.13 OAG05954.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OAG05954.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ATP_bind_1 PF03029.17 OAG05954.1 - 0.18 11.6 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 OAG05954.1 - 0.37 10.5 3.0 20 4.9 1.3 2.7 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system BCDHK_Adom3 PF10436.9 OAG05955.1 - 1.8e-44 151.4 0.1 2.8e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAG05955.1 - 4.4e-10 40.1 0.0 2.5e-08 34.4 0.0 2.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG05955.1 - 0.16 11.8 0.0 0.99 9.2 0.0 2.1 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_115 PF15979.5 OAG05956.1 - 3.5e-133 444.3 0.9 4.8e-133 443.8 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 OAG05956.1 - 1.2e-49 168.5 0.2 3.7e-49 166.9 0.0 1.9 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain Pas_Saposin PF09016.10 OAG05956.1 - 0.029 14.7 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 Pas factor saposin fold S_layer_C PF05124.12 OAG05956.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region Cutinase PF01083.22 OAG05957.1 - 1.4e-22 80.5 0.2 7e-21 75.0 0.2 2.1 2 0 0 2 2 2 2 Cutinase DUF2374 PF09574.10 OAG05957.1 - 0.052 13.4 0.3 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Glyoxalase PF00903.25 OAG05958.1 - 1.5e-06 28.4 0.3 2.3e-06 27.8 0.3 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG05958.1 - 0.0026 18.5 0.0 0.0033 18.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain DUF4210 PF13915.6 OAG05959.1 - 2.6e-33 114.4 0.2 3.8e-32 110.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 OAG05959.1 - 9.6e-25 86.5 0.7 2e-24 85.5 0.7 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 OAG05960.1 - 3.8e-06 27.0 17.2 7e-06 26.1 17.2 1.4 1 1 0 1 1 1 1 rRNA processing Trypan_PARP PF05887.11 OAG05960.1 - 0.1 12.6 16.5 0.033 14.2 13.5 1.7 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 OAG05960.1 - 5.7 7.5 26.6 1.1 9.8 18.2 2.3 1 1 1 2 2 2 0 TonB polyproline region Myb_DNA-binding PF00249.31 OAG05961.1 - 3.2e-34 116.9 13.9 1.7e-14 53.7 0.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG05961.1 - 3.3e-26 91.3 4.5 3.4e-13 49.6 0.4 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG05961.1 - 8.7e-05 22.3 0.3 0.42 10.5 0.0 2.7 1 1 0 2 2 2 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OAG05961.1 - 0.007 16.6 3.0 2.6 8.4 0.2 3.3 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 OAG05961.1 - 0.01 16.0 0.6 0.81 9.9 0.0 2.8 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 OAG05961.1 - 0.072 13.2 0.3 1.2 9.2 0.0 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) BSP PF04450.12 OAG05962.1 - 2.9e-74 249.3 0.0 3.4e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 OAG05962.1 - 0.0014 18.4 0.7 0.0032 17.3 0.6 1.5 1 1 0 1 1 1 1 SprT-like family Peptidase_M1 PF01433.20 OAG05962.1 - 0.013 15.1 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Peptidase family M1 domain Peptidase_M91 PF14891.6 OAG05962.1 - 0.028 14.7 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 Effector protein Aspzincin_M35 PF14521.6 OAG05962.1 - 0.12 12.9 0.4 0.29 11.7 0.1 1.8 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Peptidase_M76 PF09768.9 OAG05962.1 - 0.15 11.9 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase M76 family Metal_hydrol PF10118.9 OAG05962.1 - 0.17 11.6 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase HAD_2 PF13419.6 OAG05963.1 - 3.1e-12 46.9 0.6 4.4e-12 46.4 0.6 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG05963.1 - 4e-07 30.5 0.0 8.8e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG05963.1 - 0.0026 17.8 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like 5_nucleotid PF05761.14 OAG05963.1 - 0.014 14.3 0.3 0.15 10.9 0.4 1.9 1 1 1 2 2 2 0 5' nucleotidase family DUF4437 PF14499.6 OAG05963.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) KH_1 PF00013.29 OAG05965.1 - 1.9e-33 114.1 0.3 2.2e-07 30.6 0.0 6.2 6 0 0 6 6 6 5 KH domain Rhodanese PF00581.20 OAG05966.1 - 4.5e-15 56.1 0.0 5.1e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.26 OAG05967.1 - 5.1e-06 26.6 6.4 0.0022 18.4 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG05967.1 - 3.9e-05 24.1 6.1 0.034 15.0 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OAG05967.1 - 0.0011 19.2 0.2 0.0019 18.5 0.2 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 OAG05967.1 - 0.013 16.1 2.2 0.042 14.5 1.1 2.4 2 1 0 2 2 2 0 FOXP coiled-coil domain OrsD PF12013.8 OAG05967.1 - 0.03 14.8 2.8 0.83 10.1 0.2 2.5 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Ogr_Delta PF04606.12 OAG05967.1 - 0.042 13.8 0.5 0.31 11.1 0.0 2.3 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger Fer4_11 PF13247.6 OAG05967.1 - 0.05 13.7 1.9 0.073 13.2 1.9 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-C2H2_6 PF13912.6 OAG05967.1 - 0.059 13.4 2.5 6.4 6.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.7 OAG05968.1 - 7.6e-37 125.8 7.0 8.4e-11 42.3 0.1 5.6 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG05968.1 - 1.8e-23 82.6 5.9 2.6e-05 24.7 0.0 7.0 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG05968.1 - 1.1e-21 74.6 10.2 0.0097 16.4 0.1 10.3 10 1 1 11 11 10 5 Ankyrin repeat Ank_5 PF13857.6 OAG05968.1 - 9.6e-18 64.0 9.2 0.00027 21.2 0.0 7.6 4 3 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG05968.1 - 7.3e-11 42.0 12.2 0.19 12.2 0.2 8.0 7 1 0 7 7 6 2 Ankyrin repeat zf-C2H2 PF00096.26 OAG05968.1 - 5.7e-08 32.8 18.4 0.012 16.1 0.2 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OAG05968.1 - 6.8e-06 25.7 0.4 6.8e-06 25.7 0.4 4.0 4 0 0 4 4 4 1 C2H2-type zinc-finger domain C1_4 PF07975.12 OAG05968.1 - 0.00013 22.1 1.6 0.00013 22.1 1.6 1.7 1 1 0 1 1 1 1 TFIIH C1-like domain zf-C2H2_6 PF13912.6 OAG05968.1 - 0.0029 17.5 11.6 0.33 11.0 2.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG05968.1 - 0.02 15.7 21.8 0.34 11.9 2.5 4.1 4 0 0 4 4 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG05968.1 - 0.04 14.2 8.0 0.18 12.2 5.3 2.5 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3117 PF11314.8 OAG05968.1 - 0.046 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) zf-H2C2_2 PF13465.6 OAG05968.1 - 0.16 12.5 16.1 5.3 7.6 1.3 4.8 5 0 0 5 5 5 0 Zinc-finger double domain zf-Di19 PF05605.12 OAG05968.1 - 0.48 10.8 8.4 0.19 12.0 1.7 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 OAG05968.1 - 0.58 10.3 4.4 1.7 8.8 4.4 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 OAG05968.1 - 0.91 9.2 5.4 0.65 9.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_aberr PF17017.5 OAG05968.1 - 4.4 7.4 7.7 3.8 7.6 0.6 2.9 2 1 1 3 3 3 0 Aberrant zinc-finger COesterase PF00135.28 OAG05969.1 - 9.4e-72 242.5 0.0 1.6e-71 241.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG05969.1 - 1.3e-07 31.7 0.1 0.00075 19.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG05969.1 - 0.013 14.9 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GATA PF00320.27 OAG05970.1 - 5.5e-15 54.7 3.2 9e-15 54.0 3.2 1.4 1 0 0 1 1 1 1 GATA zinc finger Atg14 PF10186.9 OAG05970.1 - 0.011 14.9 1.8 0.017 14.2 1.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 OAG05970.1 - 0.028 12.6 0.4 0.037 12.2 0.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TF_Zn_Ribbon PF08271.12 OAG05970.1 - 0.068 12.7 0.7 0.12 11.9 0.7 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Pox_A_type_inc PF04508.12 OAG05970.1 - 0.18 11.7 4.3 12 6.0 0.0 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Tho2 PF11262.8 OAG05970.1 - 0.45 9.7 0.9 0.63 9.2 0.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 JIP_LZII PF16471.5 OAG05970.1 - 1.6 8.9 7.4 4.1 7.6 7.4 1.6 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Spc24 PF08286.11 OAG05970.1 - 2.8 8.2 5.7 3.8 7.8 3.9 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SRP68 PF16969.5 OAG05971.1 - 6.9e-173 576.6 7.1 8.2e-173 576.4 7.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PPR_2 PF13041.6 OAG05972.1 - 1.5e-23 82.7 0.0 6.7e-07 29.4 0.0 6.3 7 0 0 7 7 7 3 PPR repeat family PPR PF01535.20 OAG05972.1 - 2.2e-18 65.1 1.8 0.047 13.9 0.0 9.0 10 0 0 10 10 10 4 PPR repeat PPR_3 PF13812.6 OAG05972.1 - 2.4e-10 40.3 0.0 0.015 15.4 0.0 4.1 3 1 1 4 4 4 3 Pentatricopeptide repeat domain TPR_14 PF13428.6 OAG05972.1 - 6.9e-06 26.5 13.8 9.4 7.4 0.0 9.3 11 1 1 12 12 12 1 Tetratricopeptide repeat PPR_1 PF12854.7 OAG05972.1 - 1.7e-05 24.4 0.3 1.7 8.4 0.0 6.4 8 0 0 8 8 8 1 PPR repeat PPR_long PF17177.4 OAG05972.1 - 0.00011 21.6 0.0 0.23 10.8 0.0 2.8 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_12 PF13424.6 OAG05972.1 - 0.015 15.6 2.0 1.4 9.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG05972.1 - 0.05 13.8 0.3 83 3.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG05972.1 - 0.15 12.6 6.1 14 6.3 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG05972.1 - 1.1 10.0 5.9 18 6.2 0.1 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Patatin PF01734.22 OAG05974.1 - 9.5e-23 81.4 0.0 2.8e-22 79.9 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase GTP_EFTU PF00009.27 OAG05977.1 - 3.9e-66 222.3 0.2 5.4e-66 221.8 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAG05977.1 - 2.8e-34 117.5 0.0 8.6e-34 115.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OAG05977.1 - 6.4e-21 74.2 0.0 2.3e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG05977.1 - 5.3e-13 49.2 0.0 2.3e-12 47.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAG05977.1 - 1.8e-11 43.9 0.0 5.1e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OAG05977.1 - 0.00023 21.2 0.2 0.00056 20.0 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAST_1 PF06743.15 OAG05977.1 - 0.07 13.1 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 La PF05383.17 OAG05978.1 - 2.4e-17 62.7 0.0 3.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OAG05978.1 - 7.2e-06 25.7 0.0 1.9e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.25 OAG05979.1 - 4.3e-15 55.1 0.0 8.4e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain DUF1178 PF06676.11 OAG05979.1 - 0.11 12.9 4.8 0.26 11.7 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF4404 PF14357.6 OAG05979.1 - 0.14 12.8 0.5 0.4 11.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF3597 PF12200.8 OAG05979.1 - 5.5 7.5 6.3 1.7 9.2 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) DUF1351 PF07083.11 OAG05980.1 - 0.035 13.9 0.6 0.062 13.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) LSM PF01423.22 OAG05981.1 - 1e-14 53.9 0.0 1.4e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG05981.1 - 2.8e-05 24.1 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RAM PF15320.6 OAG05981.1 - 0.34 11.5 9.1 0.46 11.1 9.1 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Ion_trans_2 PF07885.16 OAG05982.1 - 6.4e-27 93.3 31.3 7.8e-16 57.8 6.8 3.4 4 0 0 4 4 4 2 Ion channel DUF2198 PF09964.9 OAG05982.1 - 0.059 13.4 1.4 30 4.8 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2198) Lig_chan PF00060.26 OAG05982.1 - 0.55 10.1 6.6 0.07 13.0 1.8 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel ETF PF01012.21 OAG05983.1 - 4.6e-46 157.0 0.9 8.1e-46 156.2 0.9 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OAG05983.1 - 2.5e-33 113.9 0.1 5.5e-33 112.9 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.17 OAG05984.1 - 7.9e-29 99.8 0.2 2e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 OAG05984.1 - 1.3e-25 89.2 6.9 2.4e-25 88.3 6.9 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 OAG05984.1 - 4.2e-09 36.5 0.1 7.5e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG05984.1 - 3e-06 27.4 0.4 6.1e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain PPS_PS PF02006.16 OAG05984.1 - 0.076 12.6 0.4 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase DUF5353 PF17304.2 OAG05985.1 - 1.3e-33 114.6 6.1 1.7e-33 114.2 6.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) CbtA PF09490.10 OAG05985.1 - 0.0018 18.1 0.3 0.0023 17.7 0.3 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) CEP170_C PF15308.6 OAG05985.1 - 0.051 12.1 7.6 0.062 11.9 7.6 1.0 1 0 0 1 1 1 0 CEP170 C-terminus EOS1 PF12326.8 OAG05985.1 - 0.062 13.2 0.4 0.099 12.6 0.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein Aconitase_2_N PF06434.13 OAG05985.1 - 0.1 12.2 0.6 0.17 11.5 0.6 1.4 1 1 0 1 1 1 0 Aconitate hydratase 2 N-terminus MotA_ExbB PF01618.16 OAG05985.1 - 0.16 11.8 0.6 0.4 10.4 0.3 1.8 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family ETRAMP PF09716.10 OAG05985.1 - 0.22 11.6 3.3 0.42 10.7 3.4 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Borrelia_P83 PF05262.11 OAG05985.1 - 0.81 8.1 8.7 0.93 7.9 8.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein tRNA-synt_1c PF00749.21 OAG05987.1 - 3.1e-93 312.1 0.0 1.9e-91 306.2 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAG05987.1 - 7.8e-30 104.0 0.0 1.9e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Fungal_trans_2 PF11951.8 OAG05988.1 - 8.9e-11 41.2 0.0 1.8e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Adeno_E1B_19K PF01691.16 OAG05988.1 - 0.035 13.7 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen E1-E2_ATPase PF00122.20 OAG05989.1 - 1.6e-21 76.7 0.0 4.1e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAG05989.1 - 2.1e-15 57.6 0.4 3.3e-09 37.3 1.6 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG05989.1 - 0.0007 19.6 0.0 0.059 13.5 0.1 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG05989.1 - 0.011 15.4 0.0 0.093 12.4 0.0 2.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG05989.1 - 0.027 14.1 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus G0-G1_switch_2 PF15103.6 OAG05989.1 - 0.14 12.6 0.9 2.6 8.5 0.0 2.9 2 1 0 2 2 2 0 G0/G1 switch protein 2 S6PP PF05116.13 OAG05989.1 - 0.16 11.4 0.2 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase PsbT PF01405.17 OAG05990.1 - 0.0045 16.8 1.3 0.0082 15.9 1.3 1.4 1 0 0 1 1 1 1 Photosystem II reaction centre T protein Polyketide_cyc2 PF10604.9 OAG05991.1 - 0.0045 17.3 0.1 0.006 16.9 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.16 OAG05992.1 - 2.4e-10 39.9 9.5 3e-10 39.5 9.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG05992.1 - 0.0001 21.3 2.7 0.00014 20.9 2.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 OAG05992.1 - 0.00016 20.4 4.1 0.00016 20.4 4.1 1.7 1 1 1 2 2 2 1 MFS/sugar transport protein Epimerase PF01370.21 OAG05993.1 - 5.8e-23 81.6 0.0 7.5e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG05993.1 - 1e-13 51.4 0.0 1e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG05993.1 - 1.4e-13 50.5 0.0 2.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG05993.1 - 1.8e-08 33.9 0.0 0.0036 16.5 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAG05993.1 - 2.3e-08 33.5 0.0 3.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OAG05993.1 - 3.9e-05 23.6 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG05993.1 - 0.0016 17.7 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 OAG05993.1 - 0.0017 18.5 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 OAG05993.1 - 0.0027 17.7 0.0 0.012 15.5 0.0 2.2 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 OAG05993.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 OAG05993.1 - 0.021 14.3 0.1 0.085 12.3 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase B12-binding PF02310.19 OAG05993.1 - 0.075 13.1 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain Macro PF01661.21 OAG05996.1 - 1.2e-37 128.5 0.0 2.1e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain COesterase PF00135.28 OAG05997.1 - 6.5e-93 312.3 0.0 7.5e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG05997.1 - 2.9e-06 27.3 0.2 1.8e-05 24.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG05997.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DRMBL PF07522.14 OAG06002.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Pam17 PF08566.10 OAG06003.1 - 1.6 8.5 5.8 2.3 8.0 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Glyoxalase PF00903.25 OAG06008.1 - 1.1e-08 35.4 0.0 2.1e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG06008.1 - 5.7e-07 30.3 0.0 1e-06 29.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 OAG06008.1 - 5.8e-06 26.5 0.0 1.5e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAG06008.1 - 0.0079 16.3 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain Ank_2 PF12796.7 OAG06012.1 - 8.4e-24 84.0 1.7 9.5e-16 58.2 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG06012.1 - 2.1e-21 76.0 0.3 3.6e-08 33.8 0.0 3.9 2 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG06012.1 - 3.4e-16 58.9 4.5 0.042 14.3 0.0 5.9 4 1 1 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 OAG06012.1 - 7.3e-15 53.6 1.4 0.0022 18.3 0.0 6.0 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OAG06012.1 - 9.1e-14 51.3 1.6 1.2e-06 28.6 0.1 4.4 2 1 4 6 6 5 3 Ankyrin repeats (many copies) NACHT PF05729.12 OAG06012.1 - 6.8e-10 39.1 0.1 3.4e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG06012.1 - 3.5e-06 27.5 1.8 7.7e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 OAG06012.1 - 0.00033 19.9 0.0 0.00084 18.6 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 OAG06012.1 - 0.002 18.5 0.0 0.0094 16.3 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 OAG06012.1 - 0.0036 17.6 0.0 0.029 14.7 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 OAG06012.1 - 0.0044 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAG06012.1 - 0.059 12.9 0.1 0.43 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF262 PF03235.14 OAG06012.1 - 0.092 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 LANC_like PF05147.13 OAG06012.1 - 0.13 10.9 0.1 0.2 10.2 0.1 1.3 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein DUF2075 PF09848.9 OAG06012.1 - 0.18 11.0 4.4 2.3 7.3 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) CG-1 PF03859.16 OAG06013.1 - 0.095 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 CG-1 domain Chitin_bind_1 PF00187.19 OAG06015.1 - 1.7e-09 38.0 21.7 2.1e-09 37.7 21.7 1.2 1 0 0 1 1 1 1 Chitin recognition protein zf-RRN7 PF11781.8 OAG06016.1 - 0.003 17.2 0.5 0.003 17.2 0.5 3.9 3 1 1 4 4 4 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PolC_DP2 PF03833.13 OAG06016.1 - 0.67 7.7 7.0 0.86 7.4 7.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Corona_NS8 PF12093.8 OAG06018.1 - 0.013 16.0 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 0 Coronavirus NS8 protein DUF3034 PF11231.8 OAG06018.1 - 0.2 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) BTB PF00651.31 OAG06020.1 - 1.1e-07 32.0 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4379 PF14311.6 OAG06021.1 - 0.44 10.9 3.3 1.3 9.5 2.5 2.2 1 1 1 2 2 2 0 Probable Zinc-ribbon domain adh_short_C2 PF13561.6 OAG06022.1 - 4.3e-62 209.7 1.3 1.3e-61 208.2 1.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG06022.1 - 7.7e-52 175.6 1.8 2.4e-51 174.0 1.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG06022.1 - 9.4e-08 32.2 3.4 5.8e-07 29.6 3.4 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG06022.1 - 0.0013 18.7 0.7 0.0018 18.2 0.7 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG06022.1 - 0.05 13.1 0.1 0.088 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAG06022.1 - 0.061 12.6 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TatD_DNase PF01026.21 OAG06023.1 - 6.2e-24 84.8 0.0 1e-22 80.8 0.0 2.1 1 1 0 1 1 1 1 TatD related DNase MARVEL PF01284.23 OAG06024.1 - 0.0028 17.7 3.8 0.0044 17.1 3.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Endomucin PF07010.12 OAG06024.1 - 0.1 12.6 5.9 1.8 8.5 4.0 2.3 2 0 0 2 2 2 0 Endomucin Mit_KHE1 PF10173.9 OAG06025.1 - 6.3e-57 192.7 1.2 6.3e-57 192.7 1.2 1.6 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related HET PF06985.11 OAG06026.1 - 4.6e-14 53.0 0.1 5.1e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TauD PF02668.16 OAG06027.1 - 1.2e-44 153.2 0.5 1.7e-44 152.6 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAG06029.1 - 1.8e-39 135.7 44.7 1.8e-39 135.7 44.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06029.1 - 3.2e-10 39.5 23.7 1.4e-08 34.0 10.9 3.3 2 2 0 2 2 2 2 Sugar (and other) transporter F-box PF00646.33 OAG06032.1 - 0.0082 16.0 0.2 0.022 14.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG06032.1 - 0.024 14.5 0.2 0.064 13.2 0.2 1.7 1 0 0 1 1 1 0 F-box-like FAM193_C PF15914.5 OAG06032.1 - 0.35 10.6 4.7 0.13 12.1 1.0 2.2 2 0 0 2 2 2 0 FAM193 family C-terminal NOA36 PF06524.12 OAG06032.1 - 0.81 9.0 8.6 1.3 8.2 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein NmrA PF05368.13 OAG06033.1 - 4.1e-23 82.1 0.0 5.4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG06033.1 - 5.2e-20 72.1 0.0 8.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG06033.1 - 1.3e-08 34.6 0.0 1.4e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG06033.1 - 0.00014 21.0 0.0 0.00029 20.0 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AP_endonuc_2 PF01261.24 OAG06033.1 - 0.0015 18.0 0.0 0.0042 16.5 0.0 1.8 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel 3HCDH_N PF02737.18 OAG06033.1 - 0.0027 17.6 0.1 0.0046 16.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG06033.1 - 0.0048 16.4 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAG06033.1 - 0.016 14.6 0.2 0.04 13.4 0.2 1.7 1 1 1 2 2 2 0 short chain dehydrogenase CTP_transf_like PF01467.26 OAG06033.1 - 0.018 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase-like TGS PF02824.21 OAG06033.1 - 0.042 13.9 0.0 0.22 11.6 0.0 2.2 2 1 1 3 3 3 0 TGS domain UDPG_MGDP_dh_N PF03721.14 OAG06033.1 - 0.048 13.2 0.3 1.5 8.4 0.3 2.5 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.17 OAG06033.1 - 0.067 12.3 0.0 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Ferric_reduct PF01794.19 OAG06034.1 - 3.2e-22 79.0 13.6 8.8e-22 77.5 13.6 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG06034.1 - 7e-07 29.5 0.0 0.021 14.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG06034.1 - 2.7e-06 27.4 0.1 0.0078 16.3 0.0 3.3 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 OAG06034.1 - 0.002 18.8 0.2 0.008 16.8 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF2427 PF10348.9 OAG06034.1 - 0.021 14.6 4.5 0.036 13.8 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Peptidase_S66 PF02016.15 OAG06034.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain HET PF06985.11 OAG06035.1 - 7.5e-13 49.1 6.6 7.9e-10 39.3 1.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CTP_transf_1 PF01148.20 OAG06036.1 - 2.2e-80 270.3 23.6 2.6e-80 270.0 23.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PsbX PF06596.11 OAG06036.1 - 1.4 9.0 7.1 0.21 11.6 1.6 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DUF3636 PF12331.8 OAG06037.1 - 9.8e-40 135.8 0.0 2.2e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 OAG06037.1 - 0.0012 17.5 0.8 1.9 6.9 0.0 3.2 2 1 1 3 3 3 2 DNA damage checkpoint protein FAM76 PF16046.5 OAG06037.1 - 0.0089 15.4 1.3 0.014 14.8 1.3 1.3 1 0 0 1 1 1 1 FAM76 protein FH2 PF02181.23 OAG06037.1 - 0.14 11.3 2.4 0.26 10.4 2.4 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain KfrA_N PF11740.8 OAG06037.1 - 0.15 12.8 11.6 0.41 11.3 11.6 1.7 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term APG6_N PF17675.1 OAG06037.1 - 1.4 9.5 8.8 2.6 8.6 8.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 OAG06037.1 - 1.5 8.9 8.3 3 7.9 8.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 OAG06037.1 - 1.6 8.0 11.0 2.6 7.3 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPR_2 PF13041.6 OAG06038.1 - 3e-19 69.0 3.2 2.1e-06 27.8 0.0 8.5 6 3 3 9 9 9 3 PPR repeat family PPR_3 PF13812.6 OAG06038.1 - 6.3e-18 64.6 0.0 1.2e-05 25.3 0.0 6.4 4 2 2 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 OAG06038.1 - 2.9e-13 49.1 11.1 0.0017 18.5 0.0 8.6 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 OAG06038.1 - 2.7e-10 40.0 1.1 0.00031 20.2 0.0 3.3 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAG06038.1 - 6.7e-05 22.5 2.5 0.023 14.4 0.0 5.3 6 0 0 6 6 6 1 PPR repeat TPR_2 PF07719.17 OAG06038.1 - 0.0015 18.5 1.8 5.8 7.3 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG06038.1 - 0.0018 18.2 0.2 4.7 7.5 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG06038.1 - 0.0058 16.4 0.1 9 6.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Ntox1 PF15500.6 OAG06038.1 - 0.018 15.4 0.4 0.042 14.2 0.4 1.6 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 TPR_14 PF13428.6 OAG06038.1 - 0.019 15.8 7.7 4.2 8.4 0.0 5.9 5 1 2 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG06038.1 - 0.029 14.7 0.6 19 5.6 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG06038.1 - 0.13 12.5 0.1 17 6.0 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat KNOX1 PF03790.13 OAG06038.1 - 1.3 8.8 4.0 5.7 6.8 0.3 2.5 2 0 0 2 2 2 0 KNOX1 domain Glyco_hydro_1 PF00232.18 OAG06039.1 - 4.8e-139 463.7 0.8 6e-139 463.4 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sugar_tr PF00083.24 OAG06040.1 - 3.9e-56 190.8 28.1 4.3e-56 190.7 27.3 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG06040.1 - 8.8e-24 84.1 32.4 1.3e-23 83.5 32.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 OAG06041.1 - 2.8e-55 187.8 0.0 3.8e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain ABC_membrane PF00664.23 OAG06042.1 - 8.2e-90 301.2 33.7 3.9e-45 154.6 15.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG06042.1 - 2.4e-65 219.2 0.0 3.2e-34 118.4 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG06042.1 - 6.7e-16 58.4 5.3 7.8e-09 35.3 1.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG06042.1 - 2.8e-08 34.1 1.4 0.0076 16.5 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 OAG06042.1 - 7.7e-08 32.5 0.5 0.12 12.1 0.0 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG06042.1 - 1.3e-07 31.2 0.8 0.0015 18.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG06042.1 - 1.7e-07 31.7 0.8 0.027 14.8 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG06042.1 - 1.4e-06 28.3 0.0 0.031 14.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 OAG06042.1 - 1.7e-06 27.1 0.0 0.094 11.5 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 OAG06042.1 - 8.4e-06 25.7 0.2 0.066 12.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 OAG06042.1 - 6.8e-05 22.7 5.0 0.21 11.3 0.1 3.7 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.6 OAG06042.1 - 0.00015 22.3 4.2 0.035 14.6 3.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG06042.1 - 0.00016 21.3 0.0 1 8.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 OAG06042.1 - 0.0002 21.4 0.0 0.29 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 OAG06042.1 - 0.002 17.5 1.1 0.12 11.7 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 OAG06042.1 - 0.0023 18.5 0.1 4.4 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 OAG06042.1 - 0.0041 17.1 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 OAG06042.1 - 0.0045 17.1 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 OAG06042.1 - 0.0052 17.0 1.5 0.88 9.8 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 OAG06042.1 - 0.0053 17.0 0.1 1.1 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG06042.1 - 0.011 15.9 0.0 4.3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 OAG06042.1 - 0.021 14.6 0.1 7.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 OAG06042.1 - 0.022 14.5 0.4 0.33 10.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OAG06042.1 - 0.039 13.1 0.0 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 OAG06042.1 - 0.04 13.4 0.0 6 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 OAG06042.1 - 0.052 13.2 0.3 8.7 5.9 0.0 2.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 OAG06042.1 - 0.056 13.8 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 OAG06042.1 - 0.061 13.4 3.8 1.6 8.8 0.2 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain DUF3987 PF13148.6 OAG06042.1 - 0.11 11.5 0.0 0.39 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 OAG06042.1 - 9.7 5.9 7.0 28 4.4 0.2 3.2 3 0 0 3 3 3 0 AAA domain CMD PF02627.20 OAG06043.1 - 9.3e-09 35.2 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TPR_1 PF00515.28 OAG06044.1 - 1.8e-12 46.5 9.5 9.9e-05 22.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG06044.1 - 5.8e-10 38.5 20.8 8e-05 22.5 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG06044.1 - 2.9e-09 36.5 5.6 0.014 15.1 0.5 4.3 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.6 OAG06044.1 - 4.6e-07 29.5 6.9 0.0026 17.8 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG06044.1 - 8.7e-07 28.9 1.3 0.77 10.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG06044.1 - 5e-06 26.6 4.3 8.3e-05 22.7 1.4 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG06044.1 - 2.6e-05 24.0 5.1 0.21 11.5 0.5 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG06044.1 - 4.7e-05 23.9 11.7 0.0049 17.5 1.3 4.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG06044.1 - 7.3e-05 23.3 15.4 0.064 14.1 0.7 6.5 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG06044.1 - 0.0031 17.8 12.4 0.59 10.5 0.9 5.0 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG06044.1 - 0.0084 16.1 11.0 11 6.3 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG06044.1 - 0.013 16.0 9.8 1.3 9.6 0.3 4.9 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAG06044.1 - 0.11 12.5 0.5 2.8 8.0 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG06044.1 - 0.84 9.9 6.4 0.33 11.2 1.6 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAG06044.1 - 1.5 9.6 9.8 12 6.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TauE PF01925.19 OAG06045.1 - 0.0056 16.3 0.6 0.0073 16.0 0.6 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Tim17 PF02466.19 OAG06045.1 - 0.0066 16.8 0.9 0.0066 16.8 0.9 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Rick_17kDa_Anti PF05433.15 OAG06045.1 - 0.36 10.7 25.4 0.041 13.8 18.8 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain ATPase_gene1 PF09527.10 OAG06045.1 - 0.73 10.0 7.6 1.1 9.5 7.6 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter SR-25 PF10500.9 OAG06045.1 - 0.9 9.1 15.8 1.3 8.6 15.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FemAB_like PF04339.12 OAG06046.1 - 0.12 11.5 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition MAPEG PF01124.18 OAG06047.1 - 7.2e-09 35.6 1.8 8.8e-09 35.4 1.8 1.2 1 0 0 1 1 1 1 MAPEG family Eaf7 PF07904.13 OAG06048.1 - 4.2e-26 91.4 3.7 4.8e-26 91.2 0.0 2.2 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 TLP-20 PF06088.11 OAG06048.1 - 0.15 11.9 1.8 0.23 11.3 1.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4746 PF15928.5 OAG06048.1 - 0.23 10.9 5.4 0.1 12.0 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 OAG06048.1 - 0.77 9.0 8.3 1.2 8.4 8.3 1.3 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OAG06048.1 - 1.9 8.1 10.2 0.45 10.2 6.8 1.6 2 0 0 2 2 2 0 FAM176 family SAPS PF04499.15 OAG06048.1 - 4.4 6.0 7.0 6.3 5.5 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 OAG06048.1 - 6.1 5.7 5.4 9.3 5.1 5.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FXMRP1_C_core PF12235.8 OAG06048.1 - 6.2 7.5 17.2 1.3 9.6 13.7 1.7 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Presenilin PF01080.17 OAG06048.1 - 9.2 4.9 8.6 12 4.5 8.6 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OAG06048.1 - 9.6 4.4 10.7 12 4.0 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAG06048.1 - 9.7 4.1 10.2 13 3.7 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCP_C_terminal PF04130.13 OAG06049.1 - 2.3e-69 234.2 0.3 2.3e-69 234.2 0.3 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAG06049.1 - 5.9e-31 108.2 0.0 1.1e-30 107.3 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal ATP-synt_DE_N PF02823.16 OAG06049.1 - 0.19 11.7 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Acyl_transf_3 PF01757.22 OAG06050.1 - 4.8e-20 71.9 7.5 1.3e-19 70.5 7.5 1.7 1 1 0 1 1 1 1 Acyltransferase family Aminotran_5 PF00266.19 OAG06052.1 - 1.6e-23 83.3 0.0 3.6e-23 82.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAG06052.1 - 6.6e-08 32.1 0.0 9.2e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 OAG06052.1 - 0.0024 16.7 0.0 0.0035 16.1 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 OAG06052.1 - 0.018 13.6 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme VIT PF08487.10 OAG06052.1 - 0.029 14.6 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain DUF5339 PF17274.2 OAG06053.1 - 0.14 13.1 0.2 0.36 11.7 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5339) Pkinase PF00069.25 OAG06054.1 - 1.2e-20 74.0 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG06054.1 - 4.6e-15 55.6 0.0 9.2e-15 54.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase dsrm PF00035.26 OAG06055.1 - 6.7e-05 23.5 0.0 0.00011 22.8 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 OAG06055.1 - 0.0041 17.3 0.0 0.42 10.8 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG06055.1 - 0.013 16.2 0.0 0.03 14.9 0.0 1.8 1 1 0 1 1 1 0 Ribonuclease III domain APC_u13 PF16634.5 OAG06056.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr and SAMP PfkB PF00294.24 OAG06057.1 - 1.4e-11 44.3 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.19 OAG06058.1 - 7.6e-97 324.6 18.5 7.6e-97 324.6 18.5 2.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OAG06058.1 - 3e-61 205.6 2.2 4e-61 205.2 2.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OAG06058.1 - 0.019 14.7 2.5 0.028 14.2 2.0 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor C MAAL_N PF05034.13 OAG06058.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus Calici_MSP PF05752.11 OAG06058.1 - 0.057 13.2 0.4 0.17 11.7 0.4 1.7 1 0 0 1 1 1 0 Calicivirus minor structural protein ADP_ribosyl_GH PF03747.14 OAG06059.1 - 2.3e-54 185.1 0.3 3e-54 184.7 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Protoglobin PF11563.8 OAG06059.1 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Protoglobin Rick_17kDa_Anti PF05433.15 OAG06059.1 - 0.0027 17.5 1.1 0.0027 17.5 1.1 2.7 3 0 0 3 3 3 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OAG06059.1 - 5.3 7.1 7.9 7.7 6.6 1.4 3.2 3 0 0 3 3 3 0 Glycine zipper DUF3328 PF11807.8 OAG06061.1 - 1.4e-48 165.6 0.1 1.6e-48 165.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UAF_Rrn10 PF05234.11 OAG06061.1 - 0.12 12.6 0.1 0.8 10.0 0.0 2.0 2 0 0 2 2 2 0 UAF complex subunit Rrn10 F-box-like PF12937.7 OAG06066.1 - 0.0051 16.7 0.7 0.0093 15.8 0.7 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG06066.1 - 0.022 14.7 0.3 0.054 13.4 0.3 1.7 1 0 0 1 1 1 0 F-box domain MM_CoA_mutase PF01642.22 OAG06066.1 - 0.088 11.3 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase FAS_I_H PF18314.1 OAG06067.1 - 0.16 11.6 0.4 0.2 11.2 0.4 1.1 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain Peptidase_M60 PF13402.6 OAG06068.1 - 0.00011 21.8 0.0 0.021 14.3 0.0 3.1 3 0 0 3 3 3 2 Peptidase M60, enhancin and enhancin-like IMPa_helical PF18642.1 OAG06068.1 - 0.00053 20.4 0.0 0.0015 18.9 0.0 1.7 1 1 0 1 1 1 1 Immunomodulating metalloprotease helical domain IMPa_N_2 PF18650.1 OAG06068.1 - 0.0017 17.7 0.0 0.0043 16.3 0.0 1.7 1 0 0 1 1 1 1 Immunomodulating metalloprotease N-terminal domain Lung_7-TM_R PF06814.13 OAG06069.1 - 0.28 10.4 6.6 0.4 9.9 6.6 1.1 1 0 0 1 1 1 0 Lung seven transmembrane receptor Zn_clus PF00172.18 OAG06070.1 - 1.2e-06 28.6 11.6 1.8e-06 27.9 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf_UBZ PF18439.1 OAG06070.1 - 0.44 10.2 3.0 0.76 9.4 0.0 2.5 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger TPK_catalytic PF04263.16 OAG06071.1 - 3.7e-32 110.9 0.0 6.1e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OAG06071.1 - 6.1e-17 61.1 0.1 9.7e-17 60.5 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SKN1 PF03935.15 OAG06072.1 - 1.7e-218 726.1 0.9 2e-218 725.9 0.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-CCHC_5 PF14787.6 OAG06074.1 - 0.013 15.2 6.4 0.032 13.9 4.8 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF1451 PF07295.11 OAG06074.1 - 0.52 10.3 6.7 0.49 10.4 5.3 1.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain zf-CCHC PF00098.23 OAG06074.1 - 6.4 7.0 10.6 12 6.1 6.0 2.9 2 0 0 2 2 2 0 Zinc knuckle ADH_N PF08240.12 OAG06077.1 - 1e-08 35.0 0.0 4.4e-08 33.0 0.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG06077.1 - 2e-07 31.0 0.1 4e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG06077.1 - 0.01 15.3 0.4 0.01 15.3 0.4 1.6 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 OAG06077.1 - 0.011 15.3 0.3 0.022 14.3 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family DUF2034 PF10356.9 OAG06078.1 - 3.5e-27 95.0 0.1 8.2e-15 54.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 OAG06078.1 - 1.3e-09 38.1 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 OAG06079.1 - 1.5e-41 142.0 1.8 1.6e-41 141.9 1.8 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 OAG06079.1 - 0.0066 16.5 3.6 0.016 15.3 1.2 2.7 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 APG6_N PF17675.1 OAG06079.1 - 0.025 15.1 1.5 0.025 15.1 1.5 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region CAP_N PF01213.19 OAG06079.1 - 0.03 13.8 2.2 0.046 13.2 2.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ATG16 PF08614.11 OAG06079.1 - 0.07 13.3 3.8 0.14 12.4 3.8 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GOLGA2L5 PF15070.6 OAG06079.1 - 0.075 11.7 3.3 0.1 11.2 3.3 1.3 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 TSNAXIP1_N PF15739.5 OAG06079.1 - 0.091 13.1 1.3 19 5.7 1.4 2.3 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus PI3K_P85_iSH2 PF16454.5 OAG06079.1 - 0.11 12.1 1.5 0.12 11.9 1.5 1.3 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KIX PF02172.16 OAG06079.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 KIX domain HIP1_clath_bdg PF16515.5 OAG06079.1 - 0.47 11.1 5.7 0.38 11.4 2.2 2.2 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 IL11 PF07400.11 OAG06079.1 - 5.8 6.5 5.7 1.6 8.4 0.3 2.4 1 1 2 3 3 3 0 Interleukin 11 ThrE PF06738.12 OAG06080.1 - 1.2e-60 204.9 5.0 1.2e-60 204.9 5.0 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAG06080.1 - 7.1e-08 32.7 12.0 7.1e-08 32.7 12.0 3.2 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE DUF2651 PF10852.8 OAG06080.1 - 2.8 8.6 9.7 0.086 13.5 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) MatE PF01554.18 OAG06081.1 - 3.5e-06 26.8 15.4 0.048 13.3 6.8 3.7 2 2 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAG06081.1 - 2.3 8.3 12.4 0.088 12.9 3.5 3.2 2 2 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF3328 PF11807.8 OAG06082.1 - 0.0032 17.3 1.3 0.0076 16.0 1.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4381 PF14316.6 OAG06083.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Abhydrolase_1 PF00561.20 OAG06084.1 - 5e-13 49.3 0.1 2.1e-12 47.3 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG06084.1 - 5.2e-09 37.0 1.8 1.1e-08 35.9 1.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG06084.1 - 1.3e-07 31.1 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MeaB PF03308.16 OAG06085.1 - 3.2e-05 23.1 0.1 4.6e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 OAG06085.1 - 0.00031 20.5 0.0 0.00076 19.3 0.0 1.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OAG06085.1 - 0.00052 20.2 0.1 0.007 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAG06085.1 - 0.00092 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 OAG06085.1 - 0.0017 18.9 0.0 0.0066 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 OAG06085.1 - 0.0021 17.6 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 OAG06085.1 - 0.0035 17.7 0.2 0.0057 17.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 OAG06085.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.23 OAG06085.1 - 0.023 14.8 0.2 0.038 14.0 0.2 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 OAG06085.1 - 0.035 13.7 0.1 0.075 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAG06085.1 - 0.036 13.3 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 OAG06085.1 - 0.06 13.0 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_17 PF13207.6 OAG06085.1 - 0.064 13.7 0.4 0.35 11.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAG06085.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 OAG06085.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 OAG06085.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 OAG06085.1 - 0.13 11.9 0.3 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 OAG06085.1 - 0.21 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 KaiC ADH_N PF08240.12 OAG06086.1 - 6.3e-32 109.7 0.5 6.3e-32 109.7 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG06086.1 - 9.4e-25 87.1 0.3 9.4e-25 87.1 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG06086.1 - 3.8e-08 33.1 1.6 6.2e-07 29.1 1.6 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG06086.1 - 0.00021 22.4 0.3 0.0015 19.6 0.3 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAG06086.1 - 0.0027 18.4 0.0 0.0056 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 OAG06086.1 - 0.0057 16.3 0.1 0.014 15.0 0.1 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MTS PF05175.14 OAG06086.1 - 0.046 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 2-Hacid_dh_C PF02826.19 OAG06086.1 - 0.063 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hexapep PF00132.24 OAG06086.1 - 0.21 11.4 1.8 0.3 10.9 0.3 2.2 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) adh_short_C2 PF13561.6 OAG06087.1 - 7.7e-61 205.6 6.7 8.9e-61 205.4 6.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG06087.1 - 6.8e-45 152.9 5.7 9.2e-45 152.5 5.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG06087.1 - 7.9e-18 65.0 4.7 1.1e-17 64.5 4.7 1.1 1 0 0 1 1 1 1 KR domain Phage-MuB_C PF09077.11 OAG06087.1 - 0.039 13.8 0.6 0.085 12.8 0.6 1.6 1 0 0 1 1 1 0 Mu B transposition protein, C terminal YAcAr PF10686.9 OAG06087.1 - 0.059 13.3 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family THF_DHG_CYH_C PF02882.19 OAG06087.1 - 0.08 12.3 0.3 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.6 OAG06088.1 - 4.6e-60 203.1 1.0 5.6e-60 202.8 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG06088.1 - 2.6e-44 151.0 0.8 3.4e-44 150.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG06088.1 - 8.1e-10 38.9 0.8 1.2e-09 38.3 0.8 1.3 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG06088.1 - 0.0011 19.2 0.1 0.0032 17.7 0.2 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAG06088.1 - 0.011 15.6 0.5 0.016 15.1 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG06088.1 - 0.012 15.0 0.2 0.025 13.9 0.1 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG06088.1 - 0.015 14.7 0.2 0.019 14.4 0.2 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 OAG06088.1 - 0.023 14.6 0.3 0.046 13.6 0.3 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus F420_oxidored PF03807.17 OAG06088.1 - 0.023 15.3 1.1 0.05 14.2 1.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 OAG06088.1 - 0.1 12.4 1.6 0.21 11.4 1.6 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Sugar_tr PF00083.24 OAG06089.1 - 7.6e-89 298.6 18.8 8.9e-89 298.4 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG06089.1 - 2e-29 102.6 26.3 1.9e-26 92.8 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG06089.1 - 2.1e-05 23.1 3.3 0.0002 19.9 0.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1358 PF07096.11 OAG06089.1 - 0.74 9.8 3.7 0.91 9.5 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) Fungal_trans PF04082.18 OAG06090.1 - 1.1e-20 73.8 0.5 1.6e-20 73.2 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06090.1 - 5.2e-07 29.7 14.9 7.9e-07 29.1 14.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAG06091.1 - 1.2e-27 97.0 0.3 9.1e-27 94.2 0.0 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Asp PF00026.23 OAG06092.1 - 1.7e-12 47.4 0.0 2.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 OAG06092.1 - 0.0044 15.9 0.5 0.0089 14.9 0.5 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein OEP PF02321.18 OAG06092.1 - 0.074 12.8 2.0 0.095 12.5 0.7 1.8 2 0 0 2 2 2 0 Outer membrane efflux protein Abhydrolase_3 PF07859.13 OAG06093.1 - 1.1e-33 116.9 2.2 3.9e-33 115.1 2.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG06093.1 - 7.4e-06 25.1 0.0 1.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF1338 PF07063.13 OAG06093.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) FA_desaturase PF00487.24 OAG06094.1 - 8.4e-24 84.8 20.5 1.5e-23 84.0 20.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase MFS_1 PF07690.16 OAG06096.1 - 7.2e-29 100.8 44.3 3.3e-27 95.4 22.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG06096.1 - 0.0026 16.1 2.8 0.0026 16.1 2.8 2.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DPM3 PF08285.11 OAG06096.1 - 0.75 10.0 5.6 26 5.1 2.8 3.7 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) p450 PF00067.22 OAG06097.1 - 1.5e-58 198.7 0.0 2e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.20 OAG06098.1 - 1.8e-163 544.9 9.3 1.8e-163 544.9 9.3 2.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OAG06098.1 - 9.8e-14 50.9 0.0 1.9e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 OAG06098.1 - 0.034 14.1 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain CENP-L PF13092.6 OAG06099.1 - 6e-43 146.9 0.8 8.9e-43 146.3 0.8 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 MREG PF15812.5 OAG06100.1 - 0.05 13.9 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Melanoregulin PPP4R2 PF09184.11 OAG06100.1 - 0.31 10.6 4.0 0.35 10.4 4.0 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 OAG06100.1 - 3.8 5.6 10.9 5.4 5.1 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family SKG6 PF08693.10 OAG06102.1 - 0.14 11.6 1.4 0.31 10.5 1.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Med3 PF11593.8 OAG06102.1 - 2.6 7.2 6.5 3.6 6.7 6.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal VPS13_C PF16909.5 OAG06103.1 - 0.21 11.4 0.1 0.38 10.5 0.1 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Sugar_tr PF00083.24 OAG06105.1 - 3.4e-110 369.0 21.6 3.9e-110 368.8 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG06105.1 - 1.8e-25 89.6 29.3 1.6e-18 66.8 4.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 OAG06106.1 - 3.9e-09 36.6 0.2 8e-09 35.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG06106.1 - 3.4e-07 30.1 0.0 6.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAG06106.1 - 0.00014 21.8 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Zn_clus PF00172.18 OAG06107.1 - 1.6e-07 31.3 10.0 1.6e-07 31.3 10.0 2.4 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-oxoacid_dh PF00198.23 OAG06108.1 - 2e-71 240.2 0.4 2.6e-71 239.8 0.4 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG06108.1 - 8.2e-19 67.2 0.5 2.5e-18 65.7 0.5 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Sec7 PF01369.20 OAG06109.1 - 1e-66 224.1 0.2 5.4e-66 221.8 0.0 2.5 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 OAG06109.1 - 5.6e-43 146.6 1.3 5.6e-43 146.6 1.3 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OAG06109.1 - 2.5e-35 120.2 10.0 1.7e-32 111.1 0.1 6.4 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 OAG06109.1 - 9.1e-18 64.5 0.1 9.1e-18 64.5 0.1 3.8 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Pribosyltran_N PF13793.6 OAG06110.1 - 3.9e-44 149.3 0.1 1.3e-42 144.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAG06110.1 - 3.7e-33 115.1 0.1 1.9e-26 93.2 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAG06110.1 - 9.5e-06 25.2 0.3 0.0019 17.8 0.1 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain C1_2 PF03107.16 OAG06111.1 - 0.00088 19.5 8.0 0.001 19.3 8.0 1.1 1 0 0 1 1 1 1 C1 domain zf-HIT PF04438.16 OAG06111.1 - 0.043 13.7 7.8 0.043 13.7 7.8 1.5 2 0 0 2 2 2 0 HIT zinc finger GPR15L PF15854.5 OAG06111.1 - 0.043 14.0 3.3 0.046 14.0 3.3 1.1 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Fer4_2 PF12797.7 OAG06111.1 - 0.45 10.7 9.3 0.44 10.7 1.7 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain C1_4 PF07975.12 OAG06111.1 - 0.63 10.3 10.3 0.23 11.7 2.7 2.2 2 1 0 2 2 2 0 TFIIH C1-like domain Peptidase_C2 PF00648.21 OAG06113.1 - 5.3e-64 216.1 1.8 5.2e-63 212.8 1.8 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease U79_P34 PF03064.16 OAG06113.1 - 0.027 13.8 7.1 0.045 13.1 7.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HSP70 PF00012.20 OAG06113.1 - 0.15 10.2 12.4 0.21 9.7 12.4 1.1 1 0 0 1 1 1 0 Hsp70 protein RR_TM4-6 PF06459.12 OAG06113.1 - 0.58 9.9 10.4 0.92 9.3 10.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.9 OAG06113.1 - 0.84 9.2 17.3 1.5 8.4 17.3 1.3 1 0 0 1 1 1 0 DDRGK domain CPSF100_C PF13299.6 OAG06113.1 - 5.9 7.0 12.4 2.7 8.1 9.0 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HET PF06985.11 OAG06114.1 - 1.2e-12 48.4 9.1 2.5e-10 40.9 2.4 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 OAG06114.1 - 1.7e-11 43.8 0.0 1.8e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAG06114.1 - 1.2e-07 32.3 0.0 2.5e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OAG06114.1 - 2e-07 31.2 0.0 3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_10 PF13374.6 OAG06114.1 - 2.1e-05 24.2 1.0 7.6e-05 22.5 1.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG06114.1 - 0.00018 21.2 1.8 0.00082 19.1 1.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG06114.1 - 0.0019 18.4 0.7 0.0019 18.4 0.7 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG06114.1 - 0.0095 16.0 2.3 0.0095 16.0 2.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_14 PF13173.6 OAG06114.1 - 0.027 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.6 OAG06114.1 - 0.034 15.0 3.3 0.056 14.3 1.1 2.7 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG06114.1 - 0.046 13.9 1.1 0.046 13.9 1.1 2.5 3 0 0 3 3 1 0 Tetratricopeptide repeat AAA_25 PF13481.6 OAG06114.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_6 PF13174.6 OAG06114.1 - 0.2 12.4 2.1 0.91 10.3 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG06114.1 - 0.74 10.0 4.6 0.49 10.6 0.8 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG06114.1 - 1.9 9.2 6.4 0.62 10.8 0.3 3.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Cyclin_N PF00134.23 OAG06115.1 - 3.8e-10 39.6 0.3 5.5e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain PRP38_assoc PF12871.7 OAG06115.1 - 0.03 14.9 29.0 0.074 13.7 29.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TFIIB PF00382.19 OAG06115.1 - 0.063 13.3 0.7 0.55 10.3 0.1 2.5 3 0 0 3 3 3 0 Transcription factor TFIIB repeat Parvo_coat_N PF08398.10 OAG06115.1 - 0.15 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Nucleo_P87 PF07267.11 OAG06115.1 - 2.5 6.9 5.0 3.1 6.6 5.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 p450 PF00067.22 OAG06116.1 - 1.1e-49 169.4 0.0 1.5e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 OAG06117.1 - 2.8e-07 30.3 0.1 5.1e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 OAG06117.1 - 9.5e-06 25.8 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_occluded PF16842.5 OAG06117.1 - 4.3e-05 23.3 0.0 0.00013 21.8 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG06117.1 - 0.00014 21.8 0.0 0.0005 20.0 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 OAG06117.1 - 0.009 15.9 0.2 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.15 OAG06117.1 - 0.015 14.9 0.4 0.036 13.8 0.4 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region RRM_3 PF08777.11 OAG06117.1 - 0.051 13.6 0.1 0.051 13.6 0.1 2.8 3 0 0 3 3 3 0 RNA binding motif RRM_5 PF13893.6 OAG06117.1 - 0.065 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF641 PF04859.12 OAG06117.1 - 0.07 13.5 2.4 0.15 12.4 2.4 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf_CCCH_4 PF18345.1 OAG06117.1 - 0.11 12.6 0.3 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 Zinc finger domain TMPIT PF07851.13 OAG06117.1 - 0.12 11.7 0.8 0.17 11.1 0.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein CortBP2 PF09727.9 OAG06117.1 - 0.23 11.3 7.9 0.42 10.5 7.9 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 baeRF_family3 PF18845.1 OAG06118.1 - 0.048 13.9 0.2 0.17 12.1 0.2 1.9 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 GIT1_C PF12205.8 OAG06118.1 - 0.073 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term CVNH PF08881.10 OAG06119.1 - 0.037 14.7 0.0 0.08 13.6 0.0 1.5 2 0 0 2 2 2 0 CVNH domain ATP-synt_C PF00137.21 OAG06120.1 - 1.9e-12 47.3 9.8 1.9e-12 47.3 9.8 1.9 1 1 1 2 2 2 1 ATP synthase subunit C FCD PF07729.12 OAG06121.1 - 0.011 16.2 14.1 2.4 8.6 0.3 3.5 1 1 2 3 3 3 0 FCD domain Pex19 PF04614.12 OAG06121.1 - 0.039 13.7 6.4 0.16 11.7 6.4 1.9 1 1 0 1 1 1 0 Pex19 protein family TraF_2 PF13729.6 OAG06121.1 - 0.067 12.6 7.7 0.92 8.8 2.7 2.2 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein XPC-binding PF09280.11 OAG06121.1 - 0.082 12.7 4.2 17 5.2 0.1 3.8 3 1 1 4 4 4 0 XPC-binding domain RabGAP-TBC PF00566.18 OAG06121.1 - 0.22 11.1 0.1 30 4.2 0.0 2.8 1 1 2 3 3 3 0 Rab-GTPase-TBC domain DUF4611 PF15387.6 OAG06121.1 - 0.24 11.6 3.4 1.3 9.3 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) ECH_2 PF16113.5 OAG06121.1 - 2.1 7.8 5.0 7.7 5.9 4.6 1.8 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ParE_toxin PF05016.15 OAG06121.1 - 3.1 8.5 10.4 1.8 9.2 1.3 2.8 1 1 2 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE DprA_WH PF17782.1 OAG06121.1 - 3.8 7.7 14.2 5.7 7.1 1.0 4.0 2 1 2 4 4 4 0 DprA winged helix domain FUSC PF04632.12 OAG06121.1 - 4.3 5.7 11.8 9.2 4.7 11.8 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family L27_N PF09060.10 OAG06121.1 - 8.3 6.6 6.9 9.7 6.3 0.9 3.1 3 1 1 4 4 4 0 L27_N COesterase PF00135.28 OAG06124.1 - 1.3e-85 288.2 0.0 1.7e-85 287.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG06124.1 - 3.7e-06 27.0 0.1 4.2e-05 23.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAG06125.1 - 0.014 15.2 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG06125.1 - 0.099 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3141 PF11339.8 OAG06125.1 - 0.15 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Haem_degrading PF03928.14 OAG06126.1 - 5.4e-31 107.1 1.3 6.2e-31 106.9 1.3 1.0 1 0 0 1 1 1 1 Haem-degrading Glyco_hydro_71 PF03659.14 OAG06127.1 - 4.1e-120 401.0 4.7 4.9e-120 400.8 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF5018 PF16410.5 OAG06127.1 - 0.01 14.5 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) TauD PF02668.16 OAG06128.1 - 5.9e-49 167.3 0.5 7.9e-49 166.8 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cullin PF00888.22 OAG06129.1 - 8.5e-191 635.7 13.4 1.1e-190 635.4 13.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG06129.1 - 1.3e-26 92.4 4.0 4.8e-26 90.6 4.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 OAG06129.1 - 0.0086 16.6 4.0 0.021 15.4 0.4 3.3 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal Phage_T4_Gp30_7 PF06919.11 OAG06129.1 - 0.088 13.0 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Phage Gp30.7 protein DUF3802 PF12290.8 OAG06129.1 - 0.36 11.4 3.5 0.57 10.7 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) Cupin_2 PF07883.11 OAG06130.1 - 4.8e-08 32.6 0.6 1.1e-07 31.4 0.6 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG06130.1 - 7.7e-08 32.1 0.1 1.5e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 OAG06130.1 - 0.0013 18.5 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG06130.1 - 0.0055 16.4 0.1 0.0082 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAG06130.1 - 0.0088 15.9 0.4 0.014 15.3 0.2 1.5 1 1 0 1 1 1 1 AraC-like ligand binding domain HTH_AsnC-type PF13404.6 OAG06134.1 - 0.15 11.9 1.8 0.22 11.4 0.3 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 OAG06135.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Myb_DNA-binding PF00249.31 OAG06136.1 - 1.1e-22 80.0 3.7 6.7e-12 45.4 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG06136.1 - 4.2e-16 58.9 3.5 1.9e-12 47.3 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OAG06136.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 SLIDE HTH_23 PF13384.6 OAG06136.1 - 0.084 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain MCM PF00493.23 OAG06143.1 - 3.2e-97 324.0 0.1 7.2e-97 322.9 0.2 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 OAG06143.1 - 1.4e-30 105.7 0.1 2.6e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG06143.1 - 7.4e-23 80.8 1.9 1.5e-22 79.8 1.9 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG06143.1 - 5.2e-14 52.7 0.0 1.5e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG06143.1 - 1.7e-07 30.9 0.0 2.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAG06143.1 - 0.0037 17.1 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG06143.1 - 0.0086 15.8 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain SLAIN PF15301.6 OAG06143.1 - 0.034 13.4 11.1 0.0088 15.4 8.1 1.5 1 1 0 1 1 1 0 SLAIN motif-containing family AAA_5 PF07728.14 OAG06143.1 - 0.091 12.8 0.0 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Nucleo_P87 PF07267.11 OAG06143.1 - 0.5 9.2 4.2 0.94 8.3 4.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 adh_short PF00106.25 OAG06144.1 - 4.9e-46 156.6 0.0 6.6e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG06144.1 - 7.7e-32 110.7 0.0 9.6e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG06144.1 - 1.1e-08 35.2 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG06144.1 - 4.1e-06 26.8 0.1 7.8e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG06144.1 - 7e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG06144.1 - 0.0024 17.0 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 OAG06144.1 - 0.0061 16.1 0.1 0.012 15.2 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.10 OAG06144.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 OAG06144.1 - 0.13 11.6 0.1 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Peroxidase_2 PF01328.17 OAG06145.1 - 2.1e-54 184.9 0.0 2.5e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 FAD_binding_3 PF01494.19 OAG06148.1 - 2.3e-18 66.6 0.1 6.5e-18 65.1 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG06148.1 - 5.9e-08 32.8 0.6 2.4e-07 30.9 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG06148.1 - 6.5e-08 32.2 3.0 1.3e-05 24.6 0.5 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG06148.1 - 1.7e-06 27.4 1.1 2.2e-06 27.0 1.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG06148.1 - 6.1e-06 25.6 1.2 9.9e-06 24.9 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG06148.1 - 0.00015 21.5 5.1 0.0014 18.3 2.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG06148.1 - 0.0032 16.2 1.8 0.0032 16.2 1.8 1.7 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG06148.1 - 0.0036 16.6 1.2 0.0074 15.6 1.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG06148.1 - 0.0073 15.6 0.3 0.013 14.7 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG06148.1 - 0.0081 15.5 0.6 0.013 14.9 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG06148.1 - 0.01 16.4 2.4 0.017 15.6 1.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG06148.1 - 0.019 14.3 0.3 0.1 11.9 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAG06148.1 - 0.021 14.1 0.1 0.041 13.1 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 OAG06148.1 - 0.023 13.6 0.9 0.23 10.3 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase UDG PF03167.19 OAG06148.1 - 0.045 13.7 0.0 4.8 7.1 0.0 2.3 1 1 1 2 2 2 0 Uracil DNA glycosylase superfamily 3HCDH_N PF02737.18 OAG06148.1 - 0.095 12.6 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SNARE_assoc PF09335.11 OAG06149.1 - 4.5e-18 65.9 10.7 4.5e-18 65.9 10.7 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein Phage_holin_3_6 PF07332.11 OAG06149.1 - 0.00099 19.1 14.1 0.023 14.7 1.8 2.6 2 0 0 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III YrhC PF14143.6 OAG06149.1 - 0.0024 17.9 1.0 0.0063 16.6 1.0 1.8 1 0 0 1 1 1 1 YrhC-like protein Phage_Gp23 PF10669.9 OAG06149.1 - 0.085 13.2 0.8 0.18 12.1 0.8 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4579 PF15158.6 OAG06149.1 - 0.46 10.2 2.1 0.68 9.7 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) SieB PF14163.6 OAG06149.1 - 6.3 6.3 10.3 0.28 10.6 0.8 2.9 3 1 0 3 3 3 0 Super-infection exclusion protein B Aldo_ket_red PF00248.21 OAG06150.1 - 1.8e-27 96.3 0.0 2.2e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF732 PF05305.14 OAG06151.1 - 0.045 14.1 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Lactamase_B_2 PF12706.7 OAG06152.1 - 5.1e-25 88.2 0.0 9e-24 84.1 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG06152.1 - 2.8e-08 33.8 0.0 4.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG06152.1 - 0.037 14.0 0.9 0.34 10.9 0.7 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Bac_rhamnosid_C PF17390.2 OAG06153.1 - 1.2e-11 44.2 0.2 8.5e-11 41.5 0.1 2.3 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 OAG06153.1 - 4.2e-07 29.6 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Laminin_G_3 PF13385.6 OAG06153.1 - 0.004 17.3 0.1 0.012 15.8 0.1 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OAG06153.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain DUF1080 PF06439.11 OAG06153.1 - 0.025 14.7 0.0 0.17 11.9 0.0 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1080) Laminin_G_1 PF00054.23 OAG06153.1 - 0.099 12.9 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Laminin G domain Glyco_transf_28 PF03033.20 OAG06154.1 - 1.5e-23 83.4 0.0 2.9e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG06154.1 - 6.4e-05 21.9 0.0 9.3e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 OAG06154.1 - 0.013 15.8 0.0 0.088 13.2 0.0 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 OAG06154.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 OAG06154.1 - 0.035 13.9 0.3 0.075 12.8 0.3 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal P-mevalo_kinase PF04275.14 OAG06155.1 - 2.7e-24 85.3 0.0 7.2e-24 83.9 0.0 1.7 2 0 0 2 2 2 1 Phosphomevalonate kinase Pribosyltran PF00156.27 OAG06155.1 - 1.7e-20 73.2 0.0 3.1e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 OAG06155.1 - 2.1e-16 59.9 1.3 4.7e-16 58.8 1.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG06155.1 - 0.004 17.2 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like UPRTase PF14681.6 OAG06155.1 - 0.0058 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Sigma54_activat PF00158.26 OAG06155.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Yeast-kill-tox PF09207.11 OAG06155.1 - 0.065 13.9 0.3 0.18 12.4 0.3 1.7 1 0 0 1 1 1 0 Yeast killer toxin PRTase_2 PF15609.6 OAG06155.1 - 0.18 11.3 0.1 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyl transferase GTP_cyclohydroI PF01227.22 OAG06156.1 - 4.4e-70 234.7 0.0 5e-70 234.5 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I Ank_3 PF13606.6 OAG06157.1 - 4.1e-11 42.1 3.1 0.11 13.1 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 OAG06157.1 - 1.8e-10 41.2 0.1 8.7e-08 32.7 0.0 3.4 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG06157.1 - 6.6e-10 39.1 0.3 0.0013 19.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) F-box-like PF12937.7 OAG06157.1 - 1e-09 38.1 0.4 0.00096 19.0 0.1 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 OAG06157.1 - 5.9e-05 22.8 0.1 0.033 14.1 0.0 2.7 2 0 0 2 2 2 2 F-box domain Ank PF00023.30 OAG06157.1 - 0.00014 22.1 0.3 0.063 13.8 0.0 3.4 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OAG06157.1 - 0.0024 18.4 1.3 0.12 12.9 0.1 3.4 1 1 3 4 4 4 2 Ankyrin repeats (many copies) F-box_4 PF15966.5 OAG06157.1 - 0.0029 17.5 0.1 0.21 11.5 0.0 2.3 1 1 1 2 2 2 1 F-box CFEM PF05730.11 OAG06158.1 - 2.6e-10 40.3 11.0 4.1e-10 39.6 11.0 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 OAG06158.1 - 0.00062 19.1 0.6 0.0018 17.7 0.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PTP_tm PF18861.1 OAG06158.1 - 0.002 18.1 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4448 PF14610.6 OAG06158.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Gamma-thionin PF00304.20 OAG06158.1 - 3.7 7.9 9.0 0.37 11.1 4.3 1.7 2 0 0 2 2 2 0 Gamma-thionin family DUF4397 PF14344.6 OAG06159.1 - 0.017 15.9 1.0 0.024 15.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) EIF_2_alpha PF07541.12 OAG06160.1 - 2.5e-38 130.7 0.0 5.1e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OAG06160.1 - 1.1e-13 51.4 0.9 2e-13 50.5 0.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.12 OAG06161.1 - 1.5e-08 33.8 18.3 4.6e-07 28.9 18.3 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 OAG06161.1 - 3.1e-06 26.6 22.4 7.5e-05 22.1 22.4 2.2 1 1 0 1 1 1 1 Ion transport protein HhH-GPD PF00730.25 OAG06162.1 - 5.8e-16 58.9 0.0 1.4e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 OAG06162.1 - 2.8e-09 37.0 0.0 5.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 OAG06162.1 - 1.3e-05 24.8 0.3 5.1e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAG06162.1 - 0.0061 17.1 1.8 0.51 11.0 0.0 3.3 3 1 1 4 4 4 1 Helix-hairpin-helix domain Ndc1_Nup PF09531.10 OAG06162.1 - 0.088 11.5 2.1 0.11 11.1 2.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EndIII_4Fe-2S PF10576.9 OAG06162.1 - 0.11 12.9 4.8 0.39 11.1 4.8 2.1 1 1 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III MFS_1 PF07690.16 OAG06164.1 - 8.1e-28 97.3 51.9 7.1e-19 67.9 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG06164.1 - 0.00083 18.3 22.7 0.0071 15.2 0.1 3.5 3 1 0 3 3 3 3 MFS_1 like family DUF3925 PF13063.6 OAG06164.1 - 0.1 12.9 1.0 0.44 10.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) MSP1b PF03429.13 OAG06164.1 - 0.96 7.5 2.3 1.7 6.7 2.3 1.3 1 0 0 1 1 1 0 Major surface protein 1B Glyco_transf_41 PF13844.6 OAG06165.1 - 5.4e-109 364.7 0.0 5.6e-56 189.9 0.0 3.1 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 OAG06165.1 - 1.2e-17 62.9 11.1 0.0011 18.7 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG06165.1 - 2.3e-15 55.4 17.6 0.013 15.5 0.1 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAG06165.1 - 6e-15 54.6 12.1 3.6e-05 23.4 0.4 5.7 4 1 1 5 5 5 4 TPR repeat TPR_8 PF13181.6 OAG06165.1 - 7e-12 44.6 7.9 0.00011 22.1 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG06165.1 - 2.3e-10 40.6 10.3 0.0006 20.1 0.5 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG06165.1 - 3.2e-10 39.7 4.3 0.36 11.3 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG06165.1 - 2.3e-09 36.8 11.5 0.0069 16.2 0.1 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG06165.1 - 6.6e-09 35.9 15.1 0.038 14.8 0.1 6.2 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAG06165.1 - 2.7e-07 31.0 13.1 0.0026 18.2 0.3 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG06165.1 - 7.5e-06 26.5 16.1 0.0017 19.0 0.1 4.8 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG06165.1 - 2.7e-05 23.9 6.9 0.15 12.1 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG06165.1 - 0.0047 17.1 0.7 0.16 12.2 0.5 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OAG06165.1 - 0.051 14.0 8.8 0.13 12.6 0.1 3.6 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 OAG06165.1 - 0.69 10.1 7.4 0.16 12.2 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec62 PF03839.16 OAG06166.1 - 5.7e-75 251.5 0.8 5.7e-75 251.5 0.8 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 MPM1 PF17234.2 OAG06166.1 - 0.82 9.9 3.9 13 6.0 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PEHE PF15275.6 OAG06166.1 - 2.2 8.9 6.8 2.8 8.6 2.1 2.5 2 0 0 2 2 2 0 PEHE domain Spt20 PF12090.8 OAG06166.1 - 2.6 7.6 11.1 5.7 6.5 11.1 1.6 1 0 0 1 1 1 0 Spt20 family DUF4663 PF15668.5 OAG06167.1 - 0.016 14.3 3.1 0.017 14.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) KIAA1430 PF13879.6 OAG06167.1 - 0.037 14.8 0.0 0.084 13.6 0.0 1.8 1 1 0 1 1 1 0 KIAA1430 homologue SlyX PF04102.12 OAG06167.1 - 0.061 13.9 2.7 2.4 8.8 0.1 2.3 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 OAG06167.1 - 3.5 7.5 4.8 2.4 8.0 0.5 2.0 2 0 0 2 2 2 0 Septum formation initiator MHC2-interact PF09307.10 OAG06167.1 - 4.2 7.4 7.4 0.44 10.6 3.0 1.7 2 0 0 2 2 2 0 CLIP, MHC2 interacting Acetyltransf_1 PF00583.25 OAG06169.1 - 1.7e-11 44.3 0.0 2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG06169.1 - 7e-06 26.4 0.0 9.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG06169.1 - 0.00012 21.9 0.0 0.0002 21.3 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAG06169.1 - 0.001 19.8 0.0 0.0013 19.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG06169.1 - 0.011 15.7 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aminotran_5 PF00266.19 OAG06170.1 - 5.2e-07 28.9 0.0 1.2e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG06170.1 - 0.00072 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OAG06170.1 - 0.037 12.6 0.1 0.054 12.0 0.1 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.18 OAG06171.1 - 1.3e-145 485.5 0.0 1.6e-145 485.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Zn_clus PF00172.18 OAG06172.1 - 5.4e-07 29.6 13.8 9.8e-07 28.8 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG06172.1 - 0.00046 19.3 0.0 0.00094 18.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.26 OAG06174.1 - 5.4e-107 358.7 4.9 6.6e-107 358.4 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG06174.1 - 8.9e-13 48.4 0.0 2.3e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Sugar_tr PF00083.24 OAG06175.1 - 8.4e-97 324.9 24.3 9.7e-97 324.7 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG06175.1 - 3.7e-27 95.2 26.5 6.1e-27 94.5 26.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Collectrin PF16959.5 OAG06175.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Renal amino acid transporter Glyco_hydro_3_C PF01915.22 OAG06176.1 - 3.5e-54 183.9 0.1 6.4e-54 183.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG06176.1 - 5.4e-54 183.7 0.0 8.1e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG06176.1 - 5.2e-21 74.5 1.2 1.4e-20 73.2 1.2 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain ASH PF15780.5 OAG06176.1 - 0.039 14.1 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PH_4 PF15404.6 OAG06177.1 - 7.7e-61 205.1 0.0 1.8e-60 203.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 OAG06177.1 - 6.8e-23 80.1 0.5 2.1e-22 78.5 0.5 1.9 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 OAG06177.1 - 2.1e-07 31.4 0.0 0.63 10.6 0.0 5.2 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 OAG06177.1 - 0.00015 22.0 0.0 0.096 13.0 0.0 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain Lactamase_B_4 PF13691.6 OAG06177.1 - 0.12 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease PH_11 PF15413.6 OAG06177.1 - 0.13 12.7 3.4 2.8 8.4 0.0 3.8 4 0 0 4 4 4 0 Pleckstrin homology domain T3SSipB PF16535.5 OAG06179.1 - 0.024 15.1 2.0 0.031 14.8 2.0 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 OAG06179.1 - 0.038 14.0 2.4 0.052 13.6 2.4 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CotJB PF12652.7 OAG06179.1 - 0.074 13.3 0.2 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 CotJB protein NAD_binding_10 PF13460.6 OAG06180.1 - 1.4e-09 38.1 0.0 4.9e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG06180.1 - 0.0045 16.6 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Zn_clus PF00172.18 OAG06183.1 - 6.6e-07 29.4 13.1 1.1e-06 28.6 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG06183.1 - 4.8e-05 22.3 0.0 7.6e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG06184.1 - 2.3e-19 69.6 29.5 2.3e-19 69.6 29.5 2.0 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06184.1 - 0.0015 17.4 3.2 0.0015 17.4 3.2 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter Peptidase_M56 PF05569.11 OAG06184.1 - 0.086 12.0 1.3 0.12 11.5 0.1 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 Phage_holin_7_1 PF16081.5 OAG06184.1 - 0.37 11.0 5.3 1.1 9.4 0.4 2.4 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF5336 PF17270.2 OAG06184.1 - 0.91 9.1 4.8 2.6 7.7 0.0 3.3 3 1 1 4 4 4 0 Family of unknown function (DUF5336) Glyco_tranf_2_3 PF13641.6 OAG06185.1 - 6.9e-17 62.1 0.2 1.1e-16 61.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG06185.1 - 2.4e-08 34.0 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG06185.1 - 0.052 13.0 0.1 0.3 10.6 0.1 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 21 Trp_DMAT PF11991.8 OAG06186.1 - 2.5e-75 254.2 0.0 3e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase PSI_PsaE PF02427.17 OAG06186.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE MFS_1 PF07690.16 OAG06187.1 - 1.7e-36 125.9 40.5 6.1e-36 124.1 40.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG06187.1 - 4.9e-08 31.9 14.5 1e-07 30.8 14.5 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Carn_acyltransf PF00755.20 OAG06188.1 - 1.1e-107 361.2 0.0 1.4e-107 360.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 OAG06188.1 - 4.5e-73 245.9 0.0 1.6e-72 244.1 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG06188.1 - 1.7e-54 185.5 0.7 3.2e-54 184.6 0.7 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG06188.1 - 2.4e-49 168.2 0.0 4.8e-49 167.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 OAG06188.1 - 9.6e-36 122.4 0.1 3.1e-35 120.7 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAG06188.1 - 5.6e-14 52.6 0.0 1.5e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 OAG06188.1 - 1.6e-06 28.3 0.3 4.5e-06 26.9 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 OAG06188.1 - 2.9e-05 25.1 0.1 0.00017 22.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG06188.1 - 0.00062 19.8 0.2 0.0018 18.3 0.2 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PriX PF18689.1 OAG06188.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Primase X Acyl-CoA_dh_1 PF00441.24 OAG06189.1 - 7.6e-31 107.4 0.2 1e-30 106.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG06189.1 - 2.4e-22 78.9 0.0 3.9e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG06189.1 - 1.8e-14 54.4 0.3 1.2e-13 51.7 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG06189.1 - 1.1e-05 25.7 0.1 1.7e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Esterase PF00756.20 OAG06190.1 - 2.8e-14 53.4 1.1 1.1e-13 51.5 1.1 1.8 1 1 0 1 1 1 1 Putative esterase AMPK1_CBM PF16561.5 OAG06190.1 - 0.066 13.4 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Ribonuc_L-PSP PF01042.21 OAG06191.1 - 3.7e-16 59.2 0.0 5.3e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Goodbye PF17109.5 OAG06192.1 - 6.4e-28 97.6 0.0 3.4e-27 95.3 0.0 2.4 2 0 0 2 2 1 1 fungal STAND N-terminal Goodbye domain TPR_19 PF14559.6 OAG06192.1 - 1.8e-07 31.5 16.2 0.014 15.9 0.4 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat NACHT PF05729.12 OAG06192.1 - 1.8e-06 28.0 0.0 6.9e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 NACHT domain TPR_14 PF13428.6 OAG06192.1 - 9.5e-06 26.0 14.4 0.068 14.0 0.1 6.6 4 3 3 7 7 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAG06192.1 - 4e-05 24.1 1.8 0.00024 21.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG06192.1 - 0.00031 21.0 0.9 0.0022 18.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain TPR_5 PF12688.7 OAG06192.1 - 0.00061 20.0 1.8 0.91 9.8 0.0 3.6 3 0 0 3 3 3 2 Tetratrico peptide repeat TPR_8 PF13181.6 OAG06192.1 - 0.00076 19.5 6.6 7.1 7.1 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAG06192.1 - 0.00099 18.4 0.7 0.00099 18.4 0.7 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG06192.1 - 0.0061 16.3 1.2 5 7.1 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 OAG06192.1 - 0.0067 16.7 9.3 0.3 11.5 0.4 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG06192.1 - 0.014 15.4 0.7 21 5.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG06192.1 - 0.035 14.2 7.9 3.2 8.1 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG06192.1 - 0.052 14.2 1.9 1.1e+02 3.8 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG06192.1 - 0.084 12.8 3.1 18 5.4 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PBS_linker_poly PF00427.21 OAG06192.1 - 0.11 12.6 0.3 0.95 9.5 0.1 2.7 4 0 0 4 4 2 0 Phycobilisome Linker polypeptide RNA_helicase PF00910.22 OAG06192.1 - 0.15 12.4 0.1 1.4 9.3 0.0 2.7 3 0 0 3 3 2 0 RNA helicase TPR_11 PF13414.6 OAG06192.1 - 0.24 11.1 0.4 17 5.2 0.1 3.3 3 0 0 3 3 3 0 TPR repeat BTAD PF03704.17 OAG06192.1 - 0.26 11.7 5.4 0.56 10.6 0.6 3.4 2 1 0 3 3 2 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 OAG06192.1 - 0.35 11.2 6.2 17 5.8 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG06192.1 - 0.44 11.0 3.2 24 5.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3328 PF11807.8 OAG06193.1 - 4.4e-38 131.2 0.1 5.5e-38 130.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Abhydrolase_1 PF00561.20 OAG06194.1 - 3.9e-20 72.6 0.0 1.3e-19 70.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG06194.1 - 1.1e-15 58.9 0.4 2.4e-14 54.5 0.4 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG06194.1 - 1.5e-15 57.1 0.0 3.8e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 OAG06194.1 - 6.7e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 OAG06194.1 - 0.00019 21.1 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 OAG06194.1 - 0.0058 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 OAG06194.1 - 0.0062 16.7 0.8 0.11 12.6 0.8 2.4 1 1 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 OAG06194.1 - 0.03 13.3 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 OAG06194.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 OAG06194.1 - 0.24 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Spo7 PF03907.13 OAG06195.1 - 5.2e-87 291.0 0.0 6.3e-87 290.7 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein BPD_transp_2 PF02653.16 OAG06195.1 - 0.023 13.9 0.3 0.03 13.5 0.3 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Peptidase_M6 PF05547.11 OAG06196.1 - 0.00056 18.4 1.2 0.3 9.3 1.3 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Ferric_reduct PF01794.19 OAG06197.1 - 2.4e-19 69.7 20.0 2.4e-19 69.7 20.0 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG06197.1 - 5.2e-15 55.5 0.0 1.3e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG06197.1 - 4.5e-14 52.9 0.0 7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 OAG06197.1 - 0.022 15.3 1.5 0.022 15.3 1.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF872 PF05915.12 OAG06197.1 - 0.027 14.6 2.0 0.072 13.3 2.0 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Ctr PF04145.15 OAG06198.1 - 4e-18 66.5 5.0 8.6e-18 65.4 5.0 1.5 1 1 0 1 1 1 1 Ctr copper transporter family Tox-WTIP PF15654.6 OAG06198.1 - 0.026 14.9 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif BaxI_1 PF12811.7 OAG06198.1 - 6.8 6.2 13.9 0.14 11.7 3.0 2.1 2 0 0 2 2 2 0 Bax inhibitor 1 like Glyco_hydro_39 PF01229.17 OAG06199.1 - 1.2e-05 24.2 0.1 2.8e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 Cellulase PF00150.18 OAG06199.1 - 0.0044 16.5 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyoxalase PF00903.25 OAG06202.1 - 0.048 13.9 0.0 0.049 13.8 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HET PF06985.11 OAG06205.1 - 3.1e-26 92.5 0.1 3.8e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.33 OAG06206.1 - 1.3e-06 28.1 0.5 4.8e-06 26.3 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG06206.1 - 4.7e-06 26.4 0.1 9.7e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like Helo_like_N PF17111.5 OAG06207.1 - 2.3e-72 242.8 1.2 7.9e-71 237.7 0.1 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 OAG06207.1 - 0.0025 18.0 0.5 0.038 14.2 0.0 2.6 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases SLATT_5 PF18160.1 OAG06207.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Toxin_2 PF00451.19 OAG06207.1 - 0.13 12.6 2.0 3.4 8.1 0.3 2.4 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 HsbA PF12296.8 OAG06207.1 - 0.23 11.9 4.8 0.43 11.0 0.2 3.1 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Enterotoxin_a PF01375.17 OAG06209.1 - 1.9e-36 126.0 1.4 1.9e-36 126.0 1.4 1.9 2 0 0 2 2 2 1 Heat-labile enterotoxin alpha chain Pertussis_S1 PF02917.14 OAG06209.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 FMO-like PF00743.19 OAG06210.1 - 2.7e-12 45.9 0.0 9.8e-09 34.2 0.0 2.5 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG06210.1 - 2e-10 40.4 0.0 6.2e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG06210.1 - 4.4e-07 29.4 0.0 5.5e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG06210.1 - 3e-05 23.3 0.0 4.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Ctr PF04145.15 OAG06211.1 - 1.3e-35 123.1 1.7 1.7e-35 122.8 1.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 OAG06211.1 - 0.86 9.3 7.8 0.31 10.7 3.6 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ferric_reduct PF01794.19 OAG06212.1 - 2.1e-26 92.5 8.5 4.9e-26 91.3 8.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG06212.1 - 5.1e-20 72.2 0.0 7.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG06212.1 - 1.9e-12 47.2 0.0 6.3e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 OAG06212.1 - 6.5e-06 26.8 0.0 6.4e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Pectate_lyase_3 PF12708.7 OAG06213.1 - 4.8e-57 193.3 17.1 6.4e-47 160.2 2.7 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG06213.1 - 1.1e-05 25.1 0.4 0.17 11.6 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PSCyt3 PF07627.11 OAG06214.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) zf-ACC PF17848.1 OAG06214.1 - 0.12 12.5 0.4 0.2 11.7 0.4 1.4 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain TPP_enzyme_N PF02776.18 OAG06215.1 - 1.9e-31 109.0 0.2 5e-31 107.6 0.4 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG06215.1 - 2e-19 69.9 0.0 9.2e-18 64.5 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG06215.1 - 1.2e-18 67.2 0.0 2.5e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Bac_rhamnosid_N PF08531.10 OAG06215.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain DUF872 PF05915.12 OAG06216.1 - 0.13 12.4 0.4 0.34 11.1 0.4 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) FtsL PF04999.13 OAG06216.1 - 0.61 10.1 0.0 0.61 10.1 0.0 2.6 2 1 1 3 3 3 0 Cell division protein FtsL Zn_clus PF00172.18 OAG06218.1 - 0.00014 21.9 12.5 0.00029 20.9 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_4 PF08386.10 OAG06219.1 - 1.2e-12 47.8 0.0 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 OAG06219.1 - 1.3e-12 47.9 0.6 3.3e-12 46.6 0.5 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 OAG06220.1 - 2.9e-27 95.5 37.4 2.9e-27 95.5 37.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily BNIP3 PF06553.12 OAG06220.1 - 0.021 14.5 0.8 0.034 13.8 0.8 1.2 1 0 0 1 1 1 0 BNIP3 Aldolase_II PF00596.21 OAG06221.1 - 9.6e-22 77.8 0.0 1.2e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1459 PF07312.11 OAG06222.1 - 0.065 13.5 0.1 0.078 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) GST_C_2 PF13410.6 OAG06223.1 - 1.4e-06 28.2 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG06223.1 - 0.0025 18.0 0.1 0.0082 16.3 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG06223.1 - 0.022 15.2 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG06223.1 - 0.22 11.7 0.0 0.5 10.6 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cutinase PF01083.22 OAG06224.1 - 1e-28 100.5 3.9 1e-28 100.5 3.9 1.5 2 0 0 2 2 2 1 Cutinase Ribosomal_L24e PF01246.20 OAG06225.1 - 5.3e-32 109.8 5.3 1e-31 108.9 5.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Pam16 PF03656.13 OAG06226.1 - 4.6e-06 26.7 0.0 4.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 OAG06226.1 - 0.0003 20.9 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain adh_short_C2 PF13561.6 OAG06228.1 - 2.2e-50 171.4 0.0 2.7e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG06228.1 - 8.5e-46 155.9 0.0 1.1e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG06228.1 - 4.8e-05 23.4 0.1 9.5e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG06228.1 - 0.001 18.1 0.0 0.0024 16.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG06228.1 - 0.23 10.5 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UcrQ PF02939.16 OAG06229.1 - 3.8e-24 84.4 0.5 4.6e-24 84.2 0.5 1.1 1 0 0 1 1 1 1 UcrQ family LysM PF01476.20 OAG06230.1 - 2.6e-07 30.6 0.0 4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain Peptidase_M41 PF01434.18 OAG06231.1 - 2.9e-68 229.5 0.1 2.9e-68 229.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 OAG06231.1 - 8.1e-43 146.0 0.0 2.6e-42 144.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG06231.1 - 1e-13 50.8 0.1 3e-13 49.3 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OAG06231.1 - 7.5e-11 42.4 0.2 2e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 OAG06231.1 - 0.0012 18.8 0.0 0.0051 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG06231.1 - 0.0022 18.4 0.2 0.2 12.0 0.2 2.9 1 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 OAG06231.1 - 0.0043 16.3 0.0 0.0087 15.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 OAG06231.1 - 0.005 17.1 0.7 1.2 9.4 0.2 3.5 3 1 1 4 4 4 1 AAA domain RuvB_N PF05496.12 OAG06231.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAG06231.1 - 0.043 13.9 0.1 0.21 11.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 OAG06231.1 - 0.082 13.3 0.8 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OAG06234.1 - 1e-41 142.6 0.0 4.2e-41 140.6 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG06234.1 - 2.8e-30 104.9 0.0 2.4e-29 101.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG06234.1 - 0.00025 21.1 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 OAG06234.1 - 0.025 13.3 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain CDO_I PF05995.12 OAG06235.1 - 1.2e-41 141.9 0.1 1.4e-41 141.6 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OAG06235.1 - 0.00011 21.7 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 OAG06236.1 - 3.4e-41 139.6 0.5 2.1e-40 137.0 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAG06236.1 - 1.2e-22 79.7 0.1 3.3e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAG06236.1 - 3.5e-21 75.4 0.2 1.2e-20 73.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG06236.1 - 1.7e-09 37.4 0.1 7.5e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG06236.1 - 0.00029 20.9 0.0 0.066 13.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 OAG06236.1 - 0.0014 18.2 0.1 12 5.3 0.0 3.8 2 2 2 4 4 4 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OAG06236.1 - 0.0071 15.3 0.5 0.02 13.9 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 OAG06236.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 OAG06236.1 - 0.11 12.4 1.9 3.3 7.6 0.2 3.2 2 2 1 3 3 3 0 RsgA GTPase HTH_Tnp_Tc5 PF03221.16 OAG06237.1 - 8.4e-15 54.6 0.1 1.7e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 OAG06237.1 - 5.5e-06 25.9 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 OAG06237.1 - 0.012 15.5 0.4 0.057 13.3 0.0 2.3 3 0 0 3 3 3 0 MarR family HTH_Crp_2 PF13545.6 OAG06237.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.6 OAG06237.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 OAG06237.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 OAG06237.1 - 0.27 11.5 1.0 2.9 8.2 0.0 2.8 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain Nexin_C PF08628.12 OAG06240.1 - 0.0041 17.7 0.0 0.01 16.4 0.0 1.7 1 1 1 2 2 2 1 Sorting nexin C terminal PSCyt2 PF07583.11 OAG06240.1 - 0.049 13.6 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) PXA PF02194.15 OAG06241.1 - 6e-46 156.7 0.0 8.7e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 PXA domain Med10 PF09748.9 OAG06242.1 - 2.2e-32 111.6 0.8 2.5e-32 111.4 0.8 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 OAG06242.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) PLC-beta_C PF08703.10 OAG06242.1 - 0.053 13.5 2.8 2.4 8.1 0.2 2.7 1 1 1 2 2 2 0 PLC-beta C terminal Flagellin_N PF00669.20 OAG06242.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region AA_permease_2 PF13520.6 OAG06243.1 - 1.3e-44 152.7 42.2 1.7e-44 152.4 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG06243.1 - 5.7e-20 71.4 37.0 8.1e-20 70.9 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4014 PF13198.6 OAG06244.1 - 0.017 15.5 1.0 0.06 13.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Adeno_E3_CR2 PF02439.15 OAG06244.1 - 0.032 14.0 0.0 0.032 14.0 0.0 2.9 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 YjcB PF15940.5 OAG06244.1 - 0.22 11.7 4.7 0.061 13.5 1.1 2.0 2 0 0 2 2 2 0 Family of unknown function NmrA PF05368.13 OAG06245.1 - 1.5e-35 122.9 0.0 1.7e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG06245.1 - 3.8e-13 49.7 0.0 5.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Pro_dh PF01619.18 OAG06245.1 - 0.0086 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Epimerase PF01370.21 OAG06245.1 - 0.0098 15.4 0.0 0.17 11.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 OAG06245.1 - 0.022 15.4 1.3 0.32 11.6 0.0 2.8 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 OAG06245.1 - 0.1 11.7 0.2 5.7 6.0 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 OAG06245.1 - 0.13 12.7 0.1 1.1 9.8 0.0 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain OATP PF03137.20 OAG06246.1 - 0.09 11.0 1.6 0.1 10.8 1.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family YrhK PF14145.6 OAG06246.1 - 1.1 9.2 21.9 3.1 7.7 1.5 4.6 3 2 0 3 3 3 0 YrhK-like protein LRR_6 PF13516.6 OAG06248.1 - 3.6e-19 67.1 28.6 0.07 13.2 0.0 12.7 13 0 0 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.7 OAG06248.1 - 9.2e-13 48.2 18.6 0.2 12.1 0.0 6.8 5 1 0 6 6 6 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAG06248.1 - 1.2e-08 34.7 0.1 3.8e-08 33.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF1699 PF08004.11 OAG06248.1 - 0.00094 18.9 0.3 0.31 10.7 0.0 3.1 3 1 0 3 3 3 2 Protein of unknown function (DUF1699) F-box PF00646.33 OAG06248.1 - 0.0071 16.2 0.3 0.044 13.7 0.1 2.6 2 0 0 2 2 2 1 F-box domain SAM_Ste50p PF09235.10 OAG06248.1 - 0.16 12.3 23.7 42 4.5 0.3 8.8 5 3 5 10 10 10 0 Ste50p, sterile alpha motif Pkinase PF00069.25 OAG06249.1 - 4.9e-39 134.3 0.0 7.5e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG06249.1 - 2.4e-29 102.4 0.0 3.3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG06249.1 - 0.0087 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Spt5_N PF11942.8 OAG06249.1 - 1.5 9.8 8.4 0.97 10.5 1.8 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Fungal_trans PF04082.18 OAG06251.1 - 7.6e-30 103.8 0.0 1.3e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06251.1 - 4.5e-09 36.3 11.2 9.3e-09 35.3 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG06251.1 - 0.021 13.6 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain PIF PF05092.12 OAG06251.1 - 0.13 11.0 3.1 0.21 10.3 3.1 1.2 1 0 0 1 1 1 0 Per os infectivity GST_N PF02798.20 OAG06252.1 - 2e-15 56.9 0.0 1.6e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG06252.1 - 3.7e-15 56.1 0.0 1.2e-14 54.4 0.0 1.8 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG06252.1 - 5.1e-12 45.9 0.0 1.5e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG06252.1 - 2.4e-10 40.5 0.0 4.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG06252.1 - 3e-10 40.2 0.0 6.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG06252.1 - 0.00021 21.3 0.0 0.00047 20.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4185 PF13810.6 OAG06254.1 - 3.1e-09 36.5 1.0 3.1e-09 36.5 1.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4185) DUF2510 PF10708.9 OAG06254.1 - 0.0043 16.8 0.9 0.012 15.3 0.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2510) DHDPS PF00701.22 OAG06257.1 - 4.9e-36 123.9 0.1 6e-36 123.6 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 OAG06258.1 - 5e-10 40.2 0.6 2.5e-09 38.0 0.5 2.3 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG06258.1 - 0.21 12.3 0.3 0.42 11.3 0.3 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF924 PF06041.11 OAG06259.1 - 8.8e-21 74.8 0.0 2.2e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) HET PF06985.11 OAG06260.1 - 1.4e-28 100.1 0.3 1.6e-28 99.9 0.3 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nmad5 PF18757.1 OAG06262.1 - 0.29 11.3 2.3 0.62 10.2 2.3 1.5 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 DUF5082 PF16888.5 OAG06262.1 - 1.2 9.4 4.5 0.74 10.1 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 OAG06262.1 - 4.8 7.2 8.8 1 9.4 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MFS_1 PF07690.16 OAG06263.1 - 5.6e-33 114.3 23.2 5.6e-33 114.3 23.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily AAA PF00004.29 OAG06264.1 - 7.4e-19 68.5 0.0 1.4e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG06264.1 - 5.5e-05 23.5 0.1 0.11 12.8 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 OAG06264.1 - 0.0035 17.3 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG06264.1 - 0.0039 17.6 0.2 0.04 14.3 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAG06264.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAG06264.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DnaB_C PF03796.15 OAG06264.1 - 0.04 13.2 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 OAG06264.1 - 0.074 13.1 0.0 0.45 10.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG06264.1 - 0.078 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OAG06264.1 - 0.081 13.4 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAG06264.1 - 0.1 11.9 0.7 0.52 9.6 0.2 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.6 OAG06264.1 - 0.15 12.6 0.0 0.52 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Myotub-related PF06602.14 OAG06266.1 - 1.4e-145 484.7 0.0 1.7e-145 484.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain EamA PF00892.20 OAG06267.1 - 3.5e-10 40.2 27.1 3.6e-05 24.0 15.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OAG06267.1 - 2.1e-09 37.0 1.0 3.4e-09 36.3 1.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OAG06267.1 - 3.1e-05 23.3 14.4 3.3e-05 23.3 13.5 1.5 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 OAG06267.1 - 0.00021 20.8 11.9 0.00054 19.4 0.4 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Ribosomal_S3_C PF00189.20 OAG06268.1 - 7.9e-25 87.2 0.2 4e-24 84.9 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OAG06268.1 - 6.4e-12 45.1 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 OAG06268.1 - 0.069 12.9 0.1 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 OAG06268.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Cu-oxidase_2 PF07731.14 OAG06269.1 - 3.8e-42 143.3 9.3 7.7e-42 142.3 0.2 3.4 3 2 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG06269.1 - 3e-38 130.5 5.2 3e-38 130.5 2.8 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG06269.1 - 1.7e-33 116.0 1.1 7.5e-32 110.7 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase Ribosomal_L7Ae PF01248.26 OAG06271.1 - 1.5e-26 91.9 0.9 2e-26 91.6 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAG06271.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain zf-ANAPC11 PF12861.7 OAG06272.1 - 0.084 12.9 2.1 0.2 11.8 2.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.16 OAG06272.1 - 0.19 12.0 0.3 0.19 12.0 0.3 1.9 3 0 0 3 3 3 0 FYVE-type zinc finger DUF2946 PF11162.8 OAG06272.1 - 1.7 9.3 5.4 23 5.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) DZR PF12773.7 OAG06272.1 - 4.2 7.5 8.3 4.1 7.5 3.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon HET PF06985.11 OAG06273.1 - 1.7e-17 64.1 0.0 3.7e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IU_nuc_hydro PF01156.19 OAG06274.1 - 3.2e-81 273.2 0.0 3.8e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ferric_reduct PF01794.19 OAG06275.1 - 2.8e-19 69.5 7.2 6.7e-19 68.2 7.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG06275.1 - 1.1e-12 48.4 0.0 1e-06 29.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG06275.1 - 3.1e-09 36.9 0.0 8.3e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain zf-C2H2 PF00096.26 OAG06277.1 - 4.8e-07 29.9 18.4 3.2e-05 24.1 2.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG06277.1 - 1.4e-05 25.3 6.4 2.5e-05 24.5 3.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG06277.1 - 0.0001 22.8 1.7 0.0001 22.8 1.7 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG06277.1 - 0.0031 17.5 1.3 0.0078 16.2 1.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG06277.1 - 0.0036 17.5 0.7 0.0036 17.5 0.7 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 OAG06277.1 - 0.037 14.7 10.3 0.49 11.1 2.2 3.5 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 OAG06277.1 - 0.064 13.6 2.0 0.17 12.2 2.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon BES1_N PF05687.13 OAG06277.1 - 1.1 9.6 14.1 0.35 11.2 7.4 2.4 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal DNA_pol_phi PF04931.13 OAG06277.1 - 2.7 6.0 8.2 3.9 5.4 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-TRAF PF02176.18 OAG06277.1 - 3 8.6 8.1 0.3 11.8 2.5 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger DUF3602 PF12223.8 OAG06278.1 - 1.2e-11 45.0 14.9 0.0014 19.2 1.9 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 OAG06278.1 - 0.039 13.6 5.0 1 8.9 2.1 2.8 2 1 1 3 3 3 0 GTP1/OBG Glyco_hydro_10 PF00331.20 OAG06279.1 - 3.2e-88 295.9 2.0 3.6e-88 295.8 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Acetyltransf_1 PF00583.25 OAG06282.1 - 0.00016 21.9 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG06282.1 - 0.028 14.4 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG06282.1 - 0.045 14.2 0.0 0.094 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-HYPF PF07503.12 OAG06284.1 - 1.5 8.6 4.5 0.4 10.5 0.4 2.1 2 1 1 3 3 3 0 HypF finger P16-Arc PF04699.14 OAG06285.1 - 4.3e-51 173.3 0.0 4.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) TPR_12 PF13424.6 OAG06289.1 - 1e-10 41.8 0.2 1.1e-05 25.6 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG06289.1 - 1.9e-10 40.2 0.0 4.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG06289.1 - 0.001 18.8 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG06289.1 - 0.0017 18.4 0.1 0.063 13.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG06289.1 - 0.0042 16.5 0.1 0.005 16.3 0.1 1.0 1 0 0 1 1 1 1 MalT-like TPR region DUF2225 PF09986.9 OAG06289.1 - 0.0062 16.3 0.0 0.0076 16.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.17 OAG06289.1 - 0.034 14.2 0.1 2.4 8.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3726 PF12525.8 OAG06289.1 - 0.06 13.5 0.0 7 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) DUF4534 PF15049.6 OAG06291.1 - 0.0091 15.8 0.9 0.19 11.5 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4534) MARVEL PF01284.23 OAG06291.1 - 0.061 13.3 8.7 0.13 12.3 8.7 1.5 1 1 0 1 1 1 0 Membrane-associating domain UCR_UQCRX_QCR9 PF05365.12 OAG06291.1 - 0.12 12.3 1.3 0.29 11.1 1.3 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like adh_short PF00106.25 OAG06292.1 - 9.9e-33 113.2 0.0 1.2e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG06292.1 - 1.2e-18 67.5 0.0 1.5e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG06292.1 - 0.00025 21.0 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 OAG06292.1 - 0.00087 18.5 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OAG06292.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding SET PF00856.28 OAG06293.1 - 5.1e-12 46.5 0.1 2.8e-11 44.1 0.1 2.0 1 1 0 1 1 1 1 SET domain HeLo PF14479.6 OAG06294.1 - 1.4e-09 38.1 0.0 1.5e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation zinc_ribbon_12 PF11331.8 OAG06294.1 - 0.0057 16.4 0.1 0.0098 15.7 0.1 1.4 1 0 0 1 1 1 1 Probable zinc-ribbon domain MFS_1 PF07690.16 OAG06295.1 - 1.8e-35 122.5 43.1 1.4e-33 116.3 29.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5455 PF17537.2 OAG06295.1 - 1.2 9.6 6.5 0.28 11.6 0.3 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5455) AAA_16 PF13191.6 OAG06297.1 - 6.9e-09 36.3 0.6 1.6e-08 35.2 0.6 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 OAG06297.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAG06297.1 - 0.021 15.1 0.4 0.1 12.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG06297.1 - 0.023 14.2 0.0 0.092 12.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 OAG06297.1 - 0.057 12.8 0.7 4 6.7 0.0 2.9 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 OAG06297.1 - 0.067 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5557 PF17712.1 OAG06297.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5557) CLU PF13236.6 OAG06298.1 - 2.8e-73 246.4 0.0 4.9e-73 245.6 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OAG06298.1 - 2.9e-52 177.2 0.2 1e-51 175.5 0.0 2.1 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OAG06298.1 - 2.1e-26 92.0 4.3 1.4e-11 44.5 0.0 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 OAG06298.1 - 1.1e-24 86.5 0.1 3.2e-24 85.1 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 OAG06298.1 - 4.5e-24 83.6 0.7 1.7e-06 27.7 0.1 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat DUF727 PF05303.12 OAG06298.1 - 3.6e-06 27.0 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 OAG06298.1 - 0.0011 18.9 0.1 1.2 9.5 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG06298.1 - 0.027 14.6 0.3 7.1 7.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Borrelia_P83 PF05262.11 OAG06298.1 - 1.3 7.4 7.3 2.5 6.5 7.3 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein rhaM PF05336.13 OAG06299.1 - 9.2e-36 122.2 0.2 1.1e-35 122.0 0.2 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase NACHT PF05729.12 OAG06300.1 - 1.4e-27 96.7 0.2 2.7e-27 95.7 0.2 1.5 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 OAG06300.1 - 7.9e-14 51.8 2.3 2.2e-11 44.1 0.8 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat HET PF06985.11 OAG06300.1 - 2.3e-12 47.5 10.8 1.8e-10 41.4 0.8 3.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 OAG06300.1 - 0.0042 17.3 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_19 PF13245.6 OAG06300.1 - 0.033 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4744 PF15918.5 OAG06301.1 - 2.1 9.3 5.1 9.9 7.1 5.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Cupin_1 PF00190.22 OAG06303.1 - 1e-37 129.0 0.3 7.5e-18 64.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAG06303.1 - 3.5e-21 74.7 0.0 6.1e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG06303.1 - 1.2e-07 31.3 0.0 0.00087 18.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 OAG06303.1 - 1.4e-07 31.5 0.0 8.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.19 OAG06303.1 - 1.2e-05 25.2 0.1 0.0022 17.9 0.0 2.6 3 0 0 3 3 3 1 AraC-like ligand binding domain 3-HAO PF06052.12 OAG06303.1 - 2.1e-05 24.2 0.0 0.00032 20.4 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.7 OAG06303.1 - 0.024 14.4 0.0 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Cupin CENP-C_C PF11699.8 OAG06303.1 - 0.2 11.9 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Mif2/CENP-C like ARD PF03079.14 OAG06303.1 - 0.23 11.7 0.0 1.4 9.1 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family PLDc_2 PF13091.6 OAG06304.1 - 1.9e-22 79.6 0.0 2.6e-16 59.7 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAG06304.1 - 3.8e-05 23.7 0.1 0.00038 20.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipase D Active site motif ECR1_N PF14382.6 OAG06305.1 - 1.2e-15 57.0 0.9 2.4e-15 56.0 0.9 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 OAG06305.1 - 0.0022 18.3 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 OAG06305.1 - 0.058 14.0 0.4 0.47 11.1 0.0 2.5 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 Rrp40_N PF18311.1 OAG06305.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain TMEM234 PF10639.9 OAG06308.1 - 1.1e-40 138.3 0.5 1.3e-40 138.0 0.5 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 OAG06308.1 - 0.0002 21.6 9.2 0.039 14.1 4.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family PhyH PF05721.13 OAG06309.1 - 1.9e-54 185.1 0.0 2.5e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAG06309.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Abhydrolase_1 PF00561.20 OAG06310.1 - 1.5e-07 31.4 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Rhomboid PF01694.22 OAG06312.1 - 1.5e-18 67.3 5.5 2.7e-18 66.4 4.3 1.8 1 1 1 2 2 2 1 Rhomboid family SAE2 PF08573.10 OAG06313.1 - 0.62 11.2 2.5 1.4 10.1 2.5 1.6 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus PRANC PF09372.10 OAG06314.1 - 0.032 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Mito_carr PF00153.27 OAG06315.1 - 1.2e-47 159.8 6.3 1.8e-16 59.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 OAG06316.1 - 5.7e-28 97.7 0.2 8.1e-28 97.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain KIX_2 PF16987.5 OAG06318.1 - 7.6e-06 25.8 2.1 1.6e-05 24.8 0.1 2.8 2 0 0 2 2 2 1 KIX domain R-HINP1I PF11463.8 OAG06318.1 - 0.0039 16.7 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 R.HinP1I restriction endonuclease WD40 PF00400.32 OAG06322.1 - 2.1e-23 82.1 16.2 1.7e-05 25.4 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 OAG06322.1 - 9.1e-10 38.3 0.3 2.4e-09 36.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG06322.1 - 2.4e-05 24.1 0.0 4.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAG06322.1 - 8.3e-05 21.4 0.2 0.056 12.1 0.1 3.2 2 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 OAG06322.1 - 0.00012 21.8 0.8 0.49 9.9 0.1 2.4 1 1 0 2 2 2 2 PQQ-like domain F-box_4 PF15966.5 OAG06322.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box PQQ_3 PF13570.6 OAG06322.1 - 0.1 13.1 2.2 4.5 7.9 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain HET PF06985.11 OAG06323.1 - 1.3e-27 96.9 0.4 1.6e-27 96.7 0.4 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4307 PF14155.6 OAG06324.1 - 0.087 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) TAF8_C PF10406.9 OAG06325.1 - 5.1e-20 71.8 0.8 5.1e-20 71.8 0.8 3.8 2 1 1 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 OAG06325.1 - 2.7e-10 40.1 0.0 4.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Peptidase_M20 PF01546.28 OAG06326.1 - 4.2e-34 118.1 0.0 5.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG06326.1 - 9.1e-14 51.3 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG06326.1 - 0.054 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 MRP-L20 PF12824.7 OAG06327.1 - 3.5e-52 176.9 9.1 4.4e-52 176.5 9.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 OAG06327.1 - 0.0079 16.2 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Neugrin Mitochondr_Som1 PF11093.8 OAG06329.1 - 5.7e-25 87.1 0.0 6.5e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Glyco_transf_8 PF01501.20 OAG06330.1 - 7.2e-24 84.7 1.8 6.2e-23 81.7 1.8 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OAG06330.1 - 0.029 13.7 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative FAD_binding_7 PF03441.14 OAG06331.1 - 1.2e-74 250.2 0.3 1.8e-74 249.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG06331.1 - 2.7e-37 128.3 0.0 8.9e-37 126.6 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase DUF4360 PF14273.6 OAG06332.1 - 0.00033 20.6 0.1 0.00087 19.2 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) HopA1 PF17914.1 OAG06332.1 - 0.019 14.7 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 HopA1 effector protein family Abhydrolase_6 PF12697.7 OAG06333.1 - 0.00016 22.3 0.2 0.00027 21.6 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG06333.1 - 0.0004 19.7 0.0 0.00082 18.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAG06333.1 - 0.001 18.9 0.7 0.0025 17.6 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein LMBR1 PF04791.16 OAG06333.1 - 0.24 10.3 0.8 0.3 10.0 0.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Vps5 PF09325.10 OAG06333.1 - 0.57 9.7 16.2 1.7 8.1 15.3 1.9 2 0 0 2 2 2 0 Vps5 C terminal like Borrelia_P83 PF05262.11 OAG06333.1 - 1.6 7.1 17.7 2.3 6.6 17.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Eapp_C PF10238.9 OAG06333.1 - 2.7 8.1 10.7 6 6.9 10.7 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein RR_TM4-6 PF06459.12 OAG06333.1 - 5.9 6.6 13.2 11 5.7 13.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Seryl_tRNA_N PF02403.22 OAG06333.1 - 6.1 7.1 20.0 7.3 6.9 18.7 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Apt1 PF10351.9 OAG06334.1 - 0.31 9.8 2.9 0.42 9.4 2.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2721 PF11026.8 OAG06335.1 - 0.00026 20.9 2.1 0.00042 20.2 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) DPM3 PF08285.11 OAG06335.1 - 0.067 13.4 1.5 0.68 10.2 0.0 2.4 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TetR_C_21 PF17926.1 OAG06335.1 - 0.099 12.8 0.2 0.37 10.9 0.1 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_31 PF13847.6 OAG06336.1 - 3.4e-20 72.4 0.0 4.9e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG06336.1 - 1.5e-09 38.5 0.0 3.2e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG06336.1 - 8.8e-07 29.6 0.0 1.8e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG06336.1 - 1.6e-06 28.0 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG06336.1 - 1.9e-06 28.4 0.0 4.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG06336.1 - 0.0023 17.9 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OAG06336.1 - 0.0025 17.4 0.0 0.0048 16.5 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 OAG06336.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain AdoMet_MTase PF07757.13 OAG06336.1 - 0.065 13.6 0.1 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 OAG06336.1 - 0.079 12.2 0.2 0.2 10.9 0.2 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 OAG06336.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 OAG06337.1 - 1.7e-14 53.9 0.0 3.4e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAG06337.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4149 PF13664.6 OAG06338.1 - 2.2e-24 85.7 3.0 8.3e-24 83.9 3.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 OAG06338.1 - 0.00035 20.9 0.1 0.00044 20.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Acetyltransf_3 PF13302.7 OAG06339.1 - 1.3e-13 51.8 0.0 1.8e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG06339.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAG06339.1 - 0.079 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Baculo_p26 PF04766.12 OAG06341.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein Sec34 PF04136.15 OAG06343.1 - 0.089 12.7 2.3 0.22 11.4 1.5 1.9 2 0 0 2 2 2 0 Sec34-like family HET PF06985.11 OAG06344.1 - 1.8e-29 103.0 0.1 3.5e-29 102.0 0.1 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG06345.1 - 8.3e-35 120.3 35.2 1.2e-34 119.8 35.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0182 PF03699.13 OAG06345.1 - 0.067 11.3 1.5 0.12 10.5 1.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Peptidase_A8 PF01252.18 OAG06345.1 - 1.4 9.2 6.6 0.2 11.9 0.3 2.5 2 1 0 2 2 2 0 Signal peptidase (SPase) II adh_short PF00106.25 OAG06347.1 - 4e-32 111.3 0.8 3.5e-30 104.9 0.8 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG06347.1 - 2.6e-23 82.8 0.4 2.7e-22 79.5 0.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG06347.1 - 4.4e-10 39.7 0.2 7e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 OAG06347.1 - 0.0014 19.0 0.1 0.24 11.8 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Epimerase PF01370.21 OAG06347.1 - 0.0015 18.0 0.2 0.0072 15.8 0.0 2.2 1 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG06347.1 - 0.008 15.6 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG06347.1 - 0.0099 15.4 0.5 0.17 11.4 0.0 2.4 3 0 0 3 3 3 1 NmrA-like family 3Beta_HSD PF01073.19 OAG06347.1 - 0.023 13.7 0.0 0.1 11.6 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 OAG06347.1 - 0.081 12.8 0.5 0.45 10.4 0.0 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NACHT PF05729.12 OAG06349.1 - 7.4e-15 55.3 0.7 2.1e-14 53.8 0.7 1.8 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 OAG06349.1 - 4e-12 46.7 7.5 1e-08 35.7 0.0 3.8 3 1 1 4 4 4 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 OAG06349.1 - 8.3e-08 32.8 0.1 2.6e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat CNOT11 PF10155.9 OAG06349.1 - 0.0077 16.4 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 KaiB PF07689.12 OAG06350.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiB domain Peptidase_M75 PF09375.10 OAG06352.1 - 0.32 10.4 1.7 19 4.6 1.9 2.1 2 0 0 2 2 2 0 Imelysin Abhydrolase_1 PF00561.20 OAG06353.1 - 4.4e-14 52.8 0.0 1.2e-13 51.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG06353.1 - 3e-13 50.9 0.0 4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG06353.1 - 3.9e-11 42.7 0.1 2e-10 40.4 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG06353.1 - 0.00022 20.8 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 OAG06353.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 1.5 1 1 1 2 2 2 1 Putative esterase DUF1100 PF06500.11 OAG06353.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF2048 PF09752.9 OAG06353.1 - 0.02 14.0 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Thioesterase PF00975.20 OAG06353.1 - 0.025 14.7 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 OAG06353.1 - 0.027 14.2 0.1 0.079 12.7 0.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.18 OAG06354.1 - 3.2e-29 101.8 0.1 1.1e-28 100.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06354.1 - 1e-09 38.3 11.4 1.8e-09 37.6 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAGE PF01454.19 OAG06355.1 - 3.1e-36 125.1 0.0 7.2e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 MAGE family PHD PF00628.29 OAG06355.1 - 8.1e-10 38.4 8.4 8.1e-10 38.4 8.4 1.8 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.8 OAG06355.1 - 0.6 9.8 7.2 0.25 11.1 2.1 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Chalcone_2 PF16035.5 OAG06356.1 - 4.1e-68 229.2 0.0 6e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 OAG06356.1 - 0.0048 17.0 0.0 0.024 14.8 0.0 2.1 2 0 0 2 2 2 1 Chalcone isomerase-like FAD_binding_3 PF01494.19 OAG06357.1 - 2.2e-14 53.5 0.0 4.8e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG06357.1 - 4.2e-08 33.2 0.3 0.0013 18.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG06357.1 - 0.027 13.7 0.4 0.05 12.8 0.4 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG06357.1 - 0.057 12.7 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAG06357.1 - 0.067 13.8 0.1 2.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG06357.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F-box-like PF12937.7 OAG06358.1 - 0.045 13.6 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 F-box-like Glyco_transf_90 PF05686.12 OAG06360.1 - 2.6e-10 39.8 7.7 9.2e-05 21.5 7.2 4.1 3 1 0 3 3 3 3 Glycosyl transferase family 90 Flavi_NS4A PF01350.17 OAG06360.1 - 0.16 11.9 4.3 0.12 12.2 2.0 2.0 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF4131 PF13567.6 OAG06360.1 - 2.7 7.6 12.2 2.1 8.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) IBP39 PF11422.8 OAG06361.1 - 0.044 13.6 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 Initiator binding protein 39 kDa p450 PF00067.22 OAG06362.1 - 4.4e-63 213.6 0.0 6.5e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vac_ImportDeg PF09783.9 OAG06364.1 - 8.9e-31 106.9 0.2 7e-30 104.0 0.2 2.1 1 1 0 1 1 1 1 Vacuolar import and degradation protein Pyridox_ox_2 PF12900.7 OAG06365.1 - 4.9e-37 127.1 0.0 6.3e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3022 PF11226.8 OAG06366.1 - 0.02 15.4 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) MIG-14_Wnt-bd PF06664.12 OAG06367.1 - 0.02 14.2 2.3 0.02 14.2 2.3 1.7 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion AgrB PF04647.15 OAG06367.1 - 0.46 9.8 4.8 0.65 9.3 0.8 2.4 2 1 0 2 2 2 0 Accessory gene regulator B adh_short PF00106.25 OAG06369.1 - 3.6e-41 140.8 0.0 4.6e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG06369.1 - 5.1e-24 85.1 0.0 6.8e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG06369.1 - 2.4e-10 40.6 0.0 4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG06369.1 - 0.0015 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG06369.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAG06372.1 - 2e-09 37.6 0.0 3.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG06372.1 - 3.8e-06 26.6 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 OAG06372.1 - 0.0012 18.4 0.1 0.0043 16.6 0.0 1.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ELFV_dehydrog PF00208.21 OAG06372.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AA_permease_2 PF13520.6 OAG06374.1 - 2.7e-56 191.2 34.9 3.6e-56 190.8 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG06374.1 - 9.3e-20 70.7 25.2 9.3e-20 70.7 25.2 1.8 2 0 0 2 2 2 1 Amino acid permease HEAT PF02985.22 OAG06375.1 - 6.7e-38 125.5 21.3 0.02 15.1 0.0 13.4 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.6 OAG06375.1 - 8.3e-36 122.3 5.9 3.3e-11 43.4 0.0 8.5 3 3 6 9 9 9 8 HEAT repeats Cnd1 PF12717.7 OAG06375.1 - 3.4e-12 46.7 10.2 0.0011 19.0 0.1 5.9 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG06375.1 - 6.4e-12 45.7 8.0 0.28 11.7 0.0 9.0 8 2 2 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAG06375.1 - 8.9e-12 45.5 1.6 0.00035 21.1 0.1 7.0 5 2 4 9 9 9 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAG06375.1 - 7.3e-07 28.1 3.7 2.9e-05 22.8 1.3 4.1 2 1 1 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 OAG06375.1 - 1.1e-06 28.8 5.0 0.29 11.3 0.1 4.8 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAG06375.1 - 0.0025 17.4 2.2 2.1 7.9 0.1 4.4 3 2 1 4 4 4 1 CLASP N terminal Arm PF00514.23 OAG06375.1 - 0.0091 16.0 2.2 2.1 8.5 0.0 4.2 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 OAG06375.1 - 0.0095 14.5 2.9 1.1 7.7 0.0 2.3 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit IFRD PF05004.13 OAG06375.1 - 0.038 13.1 0.4 1 8.4 0.1 3.0 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) TetR_C_16 PF17920.1 OAG06375.1 - 0.049 13.9 0.3 8.7 6.6 0.1 3.5 2 1 2 4 4 3 0 Tetracyclin repressor-like, C-terminal domain M11L PF11099.8 OAG06375.1 - 0.09 13.0 0.2 7.2 6.9 0.0 3.2 2 1 0 3 3 3 0 Apoptosis regulator M11L like Glutaredoxin PF00462.24 OAG06376.1 - 1.1e-18 67.2 0.0 1.5e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 OAG06376.1 - 0.0096 16.4 0.1 0.014 15.8 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 OAG06376.1 - 0.017 15.5 0.0 0.021 15.2 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 OAG06376.1 - 0.083 12.7 0.2 0.2 11.4 0.2 1.7 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 OAG06376.1 - 0.15 12.2 0.8 9.1 6.4 0.3 2.1 1 1 1 2 2 2 0 Thioredoxin LMBR1 PF04791.16 OAG06377.1 - 1.1e-112 377.6 8.5 1.3e-112 377.4 8.5 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4795 PF16043.5 OAG06377.1 - 0.14 11.7 0.4 0.22 11.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_Mu_Gam PF07352.12 OAG06377.1 - 0.47 10.3 2.6 0.78 9.6 2.6 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein adh_short PF00106.25 OAG06378.1 - 1.1e-14 54.4 0.0 6.9e-13 48.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG06378.1 - 8.5e-10 38.8 0.2 1.3e-09 38.2 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG06378.1 - 5.9e-05 22.7 0.1 0.00026 20.6 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 OAG06379.1 - 4.4e-08 33.1 0.0 1.6e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG06379.1 - 3.3e-07 30.9 0.0 6.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG06379.1 - 0.0001 23.0 0.0 0.00023 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG06379.1 - 0.00037 21.2 0.0 0.00071 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG06379.1 - 0.0036 17.1 0.0 0.012 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Dynactin_p62 PF05502.13 OAG06380.1 - 1.1e-193 644.4 0.6 1.3e-193 644.1 0.6 1.0 1 0 0 1 1 1 1 Dynactin p62 family C1_4 PF07975.12 OAG06380.1 - 6.2 7.1 13.5 0.63 10.3 3.4 3.3 3 0 0 3 3 3 0 TFIIH C1-like domain DUF1793 PF08760.11 OAG06382.1 - 1e-65 221.2 0.4 1.8e-65 220.4 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 OAG06382.1 - 2e-60 203.4 0.1 1.1e-47 161.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 OAG06382.1 - 3e-46 158.1 0.1 4.6e-46 157.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAG06382.1 - 0.0081 15.7 0.1 0.028 14.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) GFO_IDH_MocA PF01408.22 OAG06383.1 - 4.2e-13 50.2 0.0 6.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG06383.1 - 0.015 15.9 0.0 0.028 15.1 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ABC_tran PF00005.27 OAG06384.1 - 4.5e-49 166.5 0.0 1.8e-25 90.0 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG06384.1 - 4.2e-42 144.7 29.8 2.2e-27 96.4 16.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG06384.1 - 1.7e-10 40.7 3.9 0.062 12.7 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG06384.1 - 1.8e-09 37.8 0.9 0.01 15.6 0.0 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAG06384.1 - 5.8e-07 29.6 0.1 0.045 13.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OAG06384.1 - 9.3e-07 28.5 1.3 0.006 16.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG06384.1 - 4.6e-06 26.9 0.1 0.039 14.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAG06384.1 - 1.5e-05 24.9 0.2 0.027 14.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 OAG06384.1 - 6.2e-05 23.6 1.9 0.016 15.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OAG06384.1 - 9e-05 22.6 0.1 0.025 14.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 OAG06384.1 - 0.00026 20.1 0.2 0.023 13.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 OAG06384.1 - 0.0003 20.0 0.1 0.038 13.2 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 OAG06384.1 - 0.00044 20.7 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 OAG06384.1 - 0.00091 18.8 0.1 1.5 8.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OAG06384.1 - 0.0016 18.2 0.4 0.8 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OAG06384.1 - 0.002 17.9 0.1 0.55 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 OAG06384.1 - 0.0023 18.1 1.4 0.68 10.0 0.3 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 OAG06384.1 - 0.0026 17.3 0.9 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OAG06384.1 - 0.0044 17.2 0.0 0.09 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAG06384.1 - 0.011 15.1 0.0 4.5 6.5 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 OAG06384.1 - 0.013 16.0 0.1 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG06384.1 - 0.026 14.2 1.7 0.7 9.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OAG06384.1 - 0.027 14.4 0.4 0.67 9.8 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 OAG06384.1 - 0.027 13.3 0.2 1.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA PF00004.29 OAG06384.1 - 0.028 14.8 0.2 2.8 8.4 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 OAG06384.1 - 0.029 13.7 0.6 6.8 6.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 OAG06384.1 - 0.031 14.3 0.0 0.95 9.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OAG06384.1 - 0.043 14.0 0.2 11 6.3 0.1 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 OAG06384.1 - 0.06 13.1 0.0 12 5.6 0.1 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 OAG06384.1 - 0.11 12.1 0.1 7.4 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAG06384.1 - 0.12 12.1 0.7 6.6 6.4 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 OAG06384.1 - 0.14 11.9 0.2 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 OAG06384.1 - 0.16 11.4 0.4 8.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NACHT PF05729.12 OAG06384.1 - 0.16 11.9 1.9 1.8 8.5 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 OAG06384.1 - 0.17 11.9 0.1 6 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.11 OAG06384.1 - 0.17 10.8 0.2 1 8.2 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain NTPase_1 PF03266.15 OAG06384.1 - 0.25 11.3 2.4 15 5.5 0.1 2.5 2 0 0 2 2 2 0 NTPase dNK PF01712.19 OAG06384.1 - 0.31 10.9 0.7 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Claudin_2 PF13903.6 OAG06384.1 - 2.1 8.1 14.1 0.53 10.0 0.6 3.8 3 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Adaptin_N PF01602.20 OAG06385.1 - 3.6e-142 474.6 0.3 4.2e-142 474.4 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OAG06385.1 - 4e-23 81.8 0.0 1e-22 80.6 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAG06385.1 - 1.8e-09 37.8 6.1 4e-06 27.0 0.0 4.4 2 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG06385.1 - 1.7e-06 28.3 0.9 0.097 13.1 0.0 4.1 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 OAG06385.1 - 0.00057 19.9 2.1 5 7.6 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat CLASP_N PF12348.8 OAG06385.1 - 0.01 15.4 0.1 0.2 11.2 0.0 2.5 2 1 0 2 2 2 0 CLASP N terminal Arm PF00514.23 OAG06385.1 - 0.023 14.7 0.0 45 4.3 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3730 PF12530.8 OAG06385.1 - 0.093 12.3 0.1 1.1 8.7 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3730) MBOAT PF03062.19 OAG06386.1 - 2e-32 112.9 12.7 2e-32 112.9 12.7 2.1 1 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family DUF4123 PF13503.6 OAG06387.1 - 0.091 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) DUF3074 PF11274.8 OAG06388.1 - 1e-58 198.4 0.0 5.7e-58 195.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 OAG06388.1 - 0.00029 20.3 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 START domain Cupin_8 PF13621.6 OAG06388.1 - 9.9 5.8 7.4 18 4.9 7.4 1.4 1 0 0 1 1 1 0 Cupin-like domain Nodulin_late PF07127.11 OAG06389.1 - 0.084 13.2 1.2 0.084 13.2 1.2 2.0 2 0 0 2 2 2 0 Late nodulin protein FSH1 PF03959.13 OAG06390.1 - 6e-14 52.2 0.0 1.8e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF3530 PF12048.8 OAG06390.1 - 0.042 13.3 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_1 PF00561.20 OAG06391.1 - 4.4e-19 69.1 0.0 2.5e-18 66.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG06391.1 - 2.8e-16 59.5 0.0 4.8e-16 58.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG06391.1 - 2.2e-14 54.6 0.0 3.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 OAG06391.1 - 5.1e-08 32.3 0.0 6.8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 OAG06391.1 - 6.3e-05 21.8 0.0 9.6e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 OAG06391.1 - 0.0045 16.3 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 OAG06391.1 - 0.034 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 OAG06391.1 - 0.087 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 OAG06391.1 - 0.092 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.20 OAG06391.1 - 0.095 12.8 0.1 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 OAG06391.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) BAG PF02179.16 OAG06392.1 - 5.5e-22 78.0 0.4 9.1e-22 77.3 0.4 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 OAG06392.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family adh_short PF00106.25 OAG06393.1 - 5.1e-42 143.5 0.0 7.3e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG06393.1 - 2.5e-25 89.4 0.0 3.4e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG06393.1 - 3.4e-12 46.6 0.1 8.3e-12 45.4 0.1 1.5 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 OAG06393.1 - 4e-05 23.1 0.0 4.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAG06393.1 - 0.00041 20.3 0.4 0.00061 19.7 0.4 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_47 PF01532.20 OAG06394.1 - 1.5e-139 465.9 0.0 1.7e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Efg1 PF10153.9 OAG06395.1 - 1.5e-33 115.5 7.9 1.5e-33 115.5 7.9 2.2 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Pox_A_type_inc PF04508.12 OAG06395.1 - 0.0062 16.3 0.4 0.0062 16.3 0.4 2.5 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat ParE_toxin PF05016.15 OAG06395.1 - 0.16 12.6 2.4 0.28 11.8 0.4 2.3 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE TRAF_BIRC3_bd PF16673.5 OAG06395.1 - 0.76 9.6 4.4 0.83 9.5 0.1 2.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Atg14 PF10186.9 OAG06395.1 - 0.95 8.5 7.6 0.055 12.5 2.8 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAR2 PF05282.11 OAG06395.1 - 1.2 8.4 4.7 0.78 9.1 3.0 1.5 1 1 0 1 1 1 0 AAR2 protein Uso1_p115_C PF04871.13 OAG06395.1 - 1.6 9.1 16.9 0.43 11.0 1.9 3.5 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region D5_N PF08706.11 OAG06395.1 - 3.4 7.9 6.5 2.7 8.3 0.2 2.4 2 1 0 2 2 2 0 D5 N terminal like zinc_ribbon_16 PF17034.5 OAG06396.1 - 1.9e-18 66.9 7.4 1.9e-18 66.9 7.4 2.0 2 0 0 2 2 2 1 Zinc-ribbon like family MAGI_u5 PF16666.5 OAG06396.1 - 0.021 15.0 5.1 13 6.0 0.0 3.5 3 0 0 3 3 3 0 Unstructured region on MAGI Zn_ribbon_17 PF17120.5 OAG06396.1 - 0.046 13.3 9.5 0.08 12.6 8.3 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 OAG06396.1 - 0.17 12.2 7.0 0.092 13.0 4.0 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 OAG06396.1 - 0.64 10.3 5.2 18 5.7 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon Transp_cyt_pur PF02133.15 OAG06397.1 - 1.6e-05 23.9 52.0 0.0011 17.9 52.0 2.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1294 PF06961.13 OAG06397.1 - 0.062 13.6 0.2 0.36 11.1 0.2 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) SMP_2 PF10144.9 OAG06397.1 - 0.21 11.2 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Homeodomain PF00046.29 OAG06399.1 - 1.7e-12 47.0 0.1 5e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG06399.1 - 3.3e-06 26.9 0.3 1e-05 25.3 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.6 OAG06399.1 - 0.0065 17.2 2.5 0.0065 17.2 2.5 7.6 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG06399.1 - 0.037 14.3 7.6 1.2 9.5 0.7 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF1390 PF07150.11 OAG06399.1 - 1.6 8.4 3.0 17 5.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) zf-C2H2 PF00096.26 OAG06399.1 - 2.9 8.5 44.0 0.071 13.6 2.1 7.1 7 0 0 7 7 7 0 Zinc finger, C2H2 type Ta0938 PF11494.8 OAG06399.1 - 9.3 6.6 7.0 41 4.5 0.1 3.1 3 0 0 3 3 3 0 Ta0938 UTP15_C PF09384.10 OAG06400.1 - 7.8e-45 152.2 0.0 1.5e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OAG06400.1 - 1e-18 67.3 1.0 0.0013 19.5 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG06400.1 - 3.7e-08 33.6 0.3 0.022 15.1 0.0 4.6 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAG06400.1 - 0.1 13.1 0.2 0.8 10.3 0.2 2.5 2 0 0 2 2 2 0 PQQ-like domain Ribosomal_L22 PF00237.19 OAG06401.1 - 6.1e-24 84.2 2.1 3.5e-22 78.6 0.4 3.0 2 1 0 2 2 2 1 Ribosomal protein L22p/L17e RRM_1 PF00076.22 OAG06402.1 - 2.2e-43 145.9 1.3 7e-14 51.4 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG06402.1 - 5e-27 93.6 0.0 5.4e-23 80.7 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG06402.1 - 1.5e-07 31.3 0.1 0.077 13.0 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.6 OAG06402.1 - 0.003 18.3 0.1 19 6.4 0.0 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Lsm_interact PF05391.11 OAG06402.1 - 0.0061 16.0 0.3 0.017 14.6 0.3 1.7 1 0 0 1 1 1 1 Lsm interaction motif DUF2635 PF10948.8 OAG06402.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) IBB PF01749.20 OAG06402.1 - 7 7.2 10.3 31 5.1 10.3 2.2 1 1 0 1 1 1 0 Importin beta binding domain Sdh5 PF03937.16 OAG06403.1 - 6.3e-24 83.7 0.4 2.2e-23 82.0 0.3 1.9 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Glyco_hydro_53 PF07745.13 OAG06404.1 - 1.4e-108 362.9 0.6 1.6e-108 362.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 CorA PF01544.18 OAG06405.1 - 2e-10 40.5 0.1 2.1e-10 40.4 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0767 PF15990.5 OAG06405.1 - 0.065 13.4 0.3 0.12 12.5 0.1 1.6 1 1 1 2 2 2 0 UPF0767 family SnoaL_2 PF12680.7 OAG06406.1 - 0.041 14.5 0.0 0.055 14.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain COX_ARM PF06481.14 OAG06406.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 COX Aromatic Rich Motif DUF3089 PF11288.8 OAG06406.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) MRJP PF03022.16 OAG06407.1 - 3.7e-16 59.3 0.0 5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 OAG06407.1 - 0.016 15.2 1.6 11 6.2 0.0 3.8 3 0 0 3 3 3 0 NHL repeat TraT PF05818.12 OAG06407.1 - 0.13 11.9 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Ras PF00071.22 OAG06408.1 - 2.9e-57 192.8 0.0 3.6e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG06408.1 - 2.5e-34 118.1 0.0 4e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG06408.1 - 2.5e-14 53.1 0.0 4.6e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG06408.1 - 9.9e-06 25.2 0.0 1.6e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG06408.1 - 2e-05 24.1 0.0 2.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG06408.1 - 2.7e-05 24.2 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG06408.1 - 4.6e-05 23.9 0.5 7.7e-05 23.1 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG06408.1 - 0.0024 17.8 0.1 1.2 9.1 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase TniB PF05621.11 OAG06408.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein zf-C2H2 PF00096.26 OAG06410.1 - 0.014 15.8 3.3 0.039 14.4 3.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG06410.1 - 0.19 12.2 1.7 8.2 7.0 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain baeRF_family3 PF18845.1 OAG06411.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 EHN PF06441.12 OAG06412.1 - 2.5e-32 111.4 0.9 6e-31 107.0 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG06412.1 - 1.7e-10 41.0 0.1 2.9e-10 40.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG06412.1 - 0.00062 20.4 2.7 0.00062 20.4 2.7 1.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.18 OAG06413.1 - 7.5e-08 32.4 8.2 1.2e-07 31.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG06413.1 - 0.00022 20.2 1.0 0.00026 19.9 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain EthD PF07110.11 OAG06414.1 - 4e-10 40.7 0.1 5.3e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG06414.1 - 0.00031 21.2 0.1 0.00085 19.8 0.1 1.7 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase G-alpha PF00503.20 OAG06415.1 - 8.3e-43 146.9 0.0 9.8e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Halogen_Hydrol PF10112.9 OAG06416.1 - 0.051 13.6 4.4 1.9 8.4 0.7 2.3 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TK PF00265.18 OAG06416.1 - 0.11 12.4 5.5 0.069 13.0 3.8 1.4 1 1 0 1 1 1 0 Thymidine kinase GREB1 PF15782.5 OAG06416.1 - 0.36 7.9 13.1 0.42 7.7 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 OAG06416.1 - 7.3 6.1 13.4 9.4 5.8 13.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) tRNA-synt_1 PF00133.22 OAG06417.1 - 3.5e-224 745.5 0.0 6.1e-224 744.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG06417.1 - 1.8e-24 86.5 0.0 5.2e-24 84.9 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAG06417.1 - 7.3e-14 51.3 0.1 2.8e-05 23.1 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) S4 PF01479.25 OAG06417.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 S4 domain tRNA-synt_1e PF01406.19 OAG06417.1 - 0.082 12.2 0.3 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain NDUF_B7 PF05676.13 OAG06418.1 - 0.00047 19.8 2.1 0.26 11.0 0.6 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 OAG06418.1 - 0.00068 19.6 0.7 0.00085 19.3 0.7 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 OAG06418.1 - 0.0017 18.4 3.1 0.13 12.4 3.5 2.1 1 1 1 2 2 2 2 CHCH domain Cmc1 PF08583.10 OAG06418.1 - 0.005 16.8 2.7 0.0067 16.4 0.8 1.8 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1638 PF07796.11 OAG06418.1 - 0.037 14.1 0.4 0.037 14.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Sfi1 PF08457.10 OAG06419.1 - 1.9e-153 512.1 106.0 9.7e-151 503.1 96.6 2.1 2 0 0 2 2 2 2 Sfi1 spindle body protein Asp PF00026.23 OAG06420.1 - 6.8e-58 196.5 1.9 2.7e-49 168.3 0.7 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG06420.1 - 4.3e-09 36.9 4.0 2.2e-07 31.3 4.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RRM_1 PF00076.22 OAG06421.1 - 1.1e-22 79.6 0.0 8.7e-14 51.1 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG06421.1 - 0.0016 18.5 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 OAG06421.1 - 0.023 14.5 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 OAG06421.1 - 0.1 12.6 0.0 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SOBP PF15279.6 OAG06421.1 - 7.6 7.0 10.3 11 6.6 10.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein N_BRCA1_IG PF16158.5 OAG06422.1 - 1.1e-31 109.5 0.0 3.1e-31 108.1 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 OAG06422.1 - 2.7e-18 65.5 59.2 5.6e-07 29.3 6.3 4.3 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 OAG06422.1 - 0.016 15.5 45.1 0.12 12.8 5.6 4.5 4 0 0 4 4 4 0 C1 domain SelA PF03841.13 OAG06422.1 - 0.14 11.1 0.2 0.23 10.4 0.2 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase COesterase PF00135.28 OAG06423.1 - 1.8e-80 271.3 0.6 4.7e-69 233.6 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG06423.1 - 0.00031 20.7 0.4 0.00091 19.1 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 OAG06423.1 - 0.2 10.7 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) MFS_1 PF07690.16 OAG06424.1 - 1.9e-18 66.5 23.7 1.9e-18 66.5 23.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 OAG06424.1 - 0.014 13.3 0.0 0.021 12.7 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_holin_5_2 PF16079.5 OAG06424.1 - 1.4 9.3 5.9 0.69 10.3 0.6 3.1 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V NUDIX PF00293.28 OAG06425.1 - 6.4e-05 23.0 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain Ferric_reduct PF01794.19 OAG06426.1 - 1.7e-24 86.3 8.5 6.5e-24 84.4 8.5 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG06426.1 - 4.2e-16 59.4 0.0 1.1e-09 38.6 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG06426.1 - 1.7e-13 50.6 0.0 1.9e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain DUF1441 PF07278.11 OAG06429.1 - 0.17 11.8 1.0 0.25 11.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) Peptidase_C14 PF00656.22 OAG06431.1 - 1.4e-06 28.5 0.1 0.00044 20.3 0.0 2.1 2 0 0 2 2 2 2 Caspase domain Hen1_L PF12623.7 OAG06431.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 RNA repair, ligase-Pnkp-associating, region of Hen1 Aldo_ket_red PF00248.21 OAG06432.1 - 7.8e-62 209.1 0.0 9.1e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Steroid_dh PF02544.16 OAG06433.1 - 1.7e-09 37.8 0.2 3.6e-09 36.8 0.2 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ank_2 PF12796.7 OAG06434.1 - 4.5e-17 62.4 0.0 4.8e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG06434.1 - 2.7e-13 49.8 0.1 4e-05 23.8 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG06434.1 - 8.3e-12 45.4 0.0 0.011 16.3 0.0 4.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG06434.1 - 1.9e-06 27.8 0.1 3.3 8.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OAG06434.1 - 3.8e-06 27.1 2.1 0.14 12.6 0.1 4.6 3 1 1 4 4 4 1 Ankyrin repeat Rotamase_3 PF13616.6 OAG06435.1 - 2e-14 54.1 0.0 3.8e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OAG06435.1 - 1.3e-13 51.7 0.0 1.7e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OAG06435.1 - 0.0012 19.7 0.0 0.0014 19.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain ARGLU PF15346.6 OAG06436.1 - 0.0041 17.0 2.6 0.0082 16.0 2.6 1.4 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 DHC PF09626.10 OAG06436.1 - 0.015 16.2 1.6 0.067 14.1 0.5 2.5 2 1 1 3 3 3 0 Dihaem cytochrome c Spt5_N PF11942.8 OAG06436.1 - 0.025 15.5 5.7 0.053 14.5 5.7 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SLY PF12485.8 OAG06436.1 - 0.084 13.6 2.0 0.15 12.8 2.0 1.4 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein CDC45 PF02724.14 OAG06436.1 - 0.12 10.7 3.1 0.16 10.2 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PRP1_N PF06424.12 OAG06436.1 - 0.15 12.5 4.9 0.25 11.8 4.9 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal HK97-gp10_like PF04883.12 OAG06436.1 - 0.24 12.4 5.8 0.1 13.6 2.8 1.9 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component PAC4 PF16093.5 OAG06436.1 - 0.3 11.3 8.6 3.7e+02 1.4 8.7 3.3 2 1 0 2 2 2 0 Proteasome assembly chaperone 4 Ank_2 PF12796.7 OAG06437.1 - 4.2e-05 24.0 0.1 0.00012 22.6 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG06437.1 - 0.18 12.4 2.6 38 5.3 0.1 4.1 4 0 0 4 4 4 0 Ankyrin repeat Acetyltransf_3 PF13302.7 OAG06438.1 - 2.6e-17 63.8 0.0 3e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG06438.1 - 1.3e-06 28.6 0.0 2.8e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OAG06438.1 - 0.00041 20.0 0.0 0.00086 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG06438.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein HET PF06985.11 OAG06439.1 - 1.1e-23 84.2 0.0 1.8e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pro_CA PF00484.19 OAG06441.1 - 1.9e-50 171.2 0.0 2.7e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF3253 PF11625.8 OAG06442.1 - 1.9e-25 88.9 0.0 2.2e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) Latarcin PF10279.9 OAG06442.1 - 0.068 13.6 0.2 0.11 12.9 0.2 1.4 1 0 0 1 1 1 0 Latarcin precursor DUF4476 PF14771.6 OAG06443.1 - 0.0033 17.7 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) Rep_4 PF05797.11 OAG06444.1 - 0.041 13.0 1.8 0.045 12.9 1.8 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) GnsAB_toxin PF08178.11 OAG06444.1 - 0.046 13.7 1.0 0.046 13.7 1.0 1.9 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Borrelia_P83 PF05262.11 OAG06444.1 - 0.054 12.0 9.5 0.063 11.8 9.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF883 PF05957.13 OAG06444.1 - 0.3 11.7 10.1 0.61 10.7 7.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PIN_8 PF18476.1 OAG06444.1 - 0.78 9.5 5.9 1 9.2 5.7 1.2 1 1 0 1 1 1 0 PIN like domain DUF4407 PF14362.6 OAG06444.1 - 1.5 8.1 10.8 2 7.7 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rotamase PF00639.21 OAG06444.1 - 1.6 9.8 6.6 3.1 8.8 6.6 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain SseC PF04888.12 OAG06444.1 - 2.8 7.5 11.0 1.3 8.5 0.4 2.2 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family YtxH PF12732.7 OAG06444.1 - 2.9 8.5 14.5 67 4.1 14.5 2.4 1 1 0 1 1 1 0 YtxH-like protein ParE_toxin PF05016.15 OAG06444.1 - 6.4 7.5 6.0 2.9 8.6 0.2 2.3 2 1 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE V-ATPase_G PF03179.15 OAG06444.1 - 9.3 6.8 15.4 7.9 7.1 13.9 1.6 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit CDT1_C PF16679.5 OAG06445.1 - 1.6e-17 63.7 0.0 3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain EphA2_TM PF14575.6 OAG06446.1 - 0.0023 18.8 0.0 0.0036 18.1 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OAG06446.1 - 0.017 15.1 1.2 0.024 14.6 0.5 1.7 1 1 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 OAG06446.1 - 0.84 9.9 7.6 0.66 10.2 3.3 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator PIRT PF15099.6 OAG06446.1 - 0.86 9.2 5.2 0.16 11.6 1.3 1.8 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family Formyl_trans_N PF00551.19 OAG06447.1 - 2.7e-39 134.8 0.2 3.3e-39 134.5 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OAG06447.1 - 4.8e-09 35.8 0.0 1.4e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OAG06447.1 - 4.4e-05 23.4 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain Ring_hydroxyl_A PF00848.19 OAG06448.1 - 1.6e-22 80.5 4.1 1.6e-20 74.0 4.1 2.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG06448.1 - 7e-14 51.5 0.0 1.4e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 OAG06448.1 - 0.042 14.0 0.1 0.087 13.0 0.1 1.5 1 0 0 1 1 1 0 Pheophorbide a oxygenase Abhydrolase_1 PF00561.20 OAG06449.1 - 2.6e-20 73.1 0.0 8e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAG06449.1 - 8.9e-15 54.7 0.0 1.9e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Pectate_lyase_3 PF12708.7 OAG06452.1 - 8.1e-06 25.8 2.3 1.6e-05 24.9 1.0 2.1 2 1 0 2 2 2 1 Pectate lyase superfamily protein DUF5631 PF18645.1 OAG06453.1 - 0.14 12.5 0.1 2.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5631) Zn_clus PF00172.18 OAG06454.1 - 3.1e-08 33.6 14.5 6e-08 32.7 14.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG06454.1 - 3.6e-07 29.3 0.0 6e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.21 OAG06456.1 - 4.3e-26 91.2 0.0 5.6e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 OAG06456.1 - 0.00079 18.7 0.0 0.0013 18.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Corona_NS8 PF12093.8 OAG06456.1 - 0.15 12.7 0.0 3 8.4 0.0 2.3 2 0 0 2 2 2 0 Coronavirus NS8 protein Na_Ca_ex PF01699.24 OAG06458.1 - 1.3e-39 135.5 41.8 2.3e-21 76.3 18.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pep1_7 PF17232.2 OAG06458.1 - 3.6 8.1 10.1 19 5.8 10.1 2.3 1 0 0 1 1 1 0 Elicitor peptide 1-7 SpoIIIAH PF12685.7 OAG06458.1 - 7.9 6.3 11.1 0.86 9.4 4.0 2.7 2 1 0 2 2 2 0 SpoIIIAH-like protein ADH_zinc_N PF00107.26 OAG06459.1 - 4.4e-10 39.7 0.1 7.7e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box PF00646.33 OAG06460.1 - 1e-05 25.3 0.1 3.5e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG06460.1 - 0.0071 16.2 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.13 OAG06460.1 - 0.2 12.4 1.3 78 4.2 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat DUF4588 PF15251.6 OAG06461.1 - 4.9e-05 23.2 0.0 7.4e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) DUF4536 PF15055.6 OAG06462.1 - 5.4e-09 36.2 6.3 4.4e-08 33.2 1.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4536) DUF5353 PF17304.2 OAG06462.1 - 1.9 8.3 4.8 3.2 7.6 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5353) Adap_comp_sub PF00928.21 OAG06463.1 - 6.3e-55 186.4 0.0 7.9e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG06463.1 - 0.048 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain SIP PF04954.13 OAG06463.1 - 0.2 12.2 0.1 0.37 11.3 0.1 1.3 1 0 0 1 1 1 0 Siderophore-interacting protein HET PF06985.11 OAG06464.1 - 6.7e-39 133.6 0.3 6.7e-39 133.6 0.3 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SKG6 PF08693.10 OAG06465.1 - 0.00024 20.4 0.1 0.00052 19.4 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 OAG06465.1 - 0.001 18.5 0.7 0.018 14.4 0.1 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5305) TMEM154 PF15102.6 OAG06465.1 - 0.001 19.0 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family PAP_PilO PF06864.12 OAG06465.1 - 0.0018 17.2 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Pilin accessory protein (PilO) Cadherin_C_2 PF16492.5 OAG06465.1 - 0.0037 18.0 0.0 0.014 16.1 0.1 1.8 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Peptidase_M56 PF05569.11 OAG06465.1 - 0.0062 15.8 0.5 0.0073 15.5 0.5 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2681 PF10883.8 OAG06465.1 - 0.0078 16.6 0.3 0.011 16.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Syndecan PF01034.20 OAG06465.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1772 PF08592.11 OAG06465.1 - 0.024 14.9 1.0 0.027 14.8 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF4448 PF14610.6 OAG06465.1 - 0.057 13.2 0.2 0.097 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Pox_A14 PF05767.12 OAG06465.1 - 0.057 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 COX4 PF02936.14 OAG06465.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF4381 PF14316.6 OAG06465.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FixQ PF05545.11 OAG06465.1 - 0.14 12.2 0.3 0.23 11.5 0.3 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TadE PF07811.12 OAG06465.1 - 3.4 8.0 7.6 1.9 8.8 1.4 2.3 2 0 0 2 2 2 0 TadE-like protein HET PF06985.11 OAG06466.1 - 1.1e-26 94.0 0.0 2.3e-26 92.9 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LOR PF04525.12 OAG06467.1 - 4.5e-24 85.1 0.1 5.7e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 LURP-one-related SseC PF04888.12 OAG06468.1 - 0.0042 16.7 3.6 0.0062 16.2 3.6 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family AMP-binding PF00501.28 OAG06470.1 - 5.6e-68 229.5 0.1 6.8e-68 229.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG06470.1 - 7e-20 71.8 0.1 1.5e-19 70.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L13 PF00572.18 OAG06471.1 - 1.7e-09 38.0 0.0 1.6e-07 31.6 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 Fungal_trans PF04082.18 OAG06472.1 - 9e-30 103.6 0.0 1.5e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06472.1 - 2.8e-11 43.3 12.6 4.6e-11 42.7 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PTS_2-RNA PF01885.16 OAG06473.1 - 1.8e-64 217.1 0.0 2.2e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family FoP_duplication PF13865.6 OAG06473.1 - 5.8 7.5 16.5 17 6.0 16.5 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.16 OAG06474.1 - 8.6e-26 90.7 35.1 8.6e-26 90.7 35.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sigma_M_inh PF17453.2 OAG06474.1 - 0.33 11.4 4.6 0.96 9.9 4.6 1.8 1 0 0 1 1 1 0 Sigma-M inhibitor 2OG-FeII_Oxy PF03171.20 OAG06475.1 - 4e-16 59.3 0.0 7.4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG06475.1 - 6e-16 59.3 0.0 1.2e-15 58.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal GFA PF04828.14 OAG06477.1 - 3.2e-21 75.5 0.4 5.2e-21 74.8 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Asp_protease_2 PF13650.6 OAG06478.1 - 0.00018 22.0 0.1 0.0011 19.6 0.0 2.2 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAG06478.1 - 0.002 18.6 0.1 0.0089 16.6 0.0 2.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease ATP-synt_DE PF00401.20 OAG06478.1 - 0.062 13.6 1.5 0.12 12.6 1.5 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF2518 PF10726.9 OAG06479.1 - 0.012 15.3 2.0 0.02 14.6 2.0 1.3 1 0 0 1 1 1 0 Protein of function (DUF2518) Pkinase PF00069.25 OAG06480.1 - 5.9e-64 216.0 0.0 7.3e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG06480.1 - 1.9e-35 122.4 0.0 2.7e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG06480.1 - 2.6e-07 30.2 0.0 4.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG06480.1 - 0.00011 21.2 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG06480.1 - 0.046 13.7 0.0 0.16 11.9 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OAG06480.1 - 0.097 12.3 0.0 1.3 8.6 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAG06480.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA_synthFbeta PF17759.1 OAG06481.1 - 4.9e-45 153.6 0.0 7.8e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OAG06481.1 - 1.2e-31 108.7 0.8 5.7e-30 103.4 0.2 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OAG06481.1 - 3.4e-24 85.4 0.0 6.7e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OAG06481.1 - 1.5e-18 66.9 0.0 9.4e-17 61.1 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain Ldh_1_N PF00056.23 OAG06483.1 - 2.1e-32 112.1 0.2 3.2e-32 111.5 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAG06483.1 - 1.8e-22 80.0 0.1 2.7e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 OAG06483.1 - 0.0091 15.6 0.1 0.052 13.2 0.1 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAG06483.1 - 0.012 16.2 0.3 0.058 14.0 0.1 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OAG06483.1 - 0.066 13.5 0.4 3.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAG06483.1 - 0.084 12.8 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 OAG06483.1 - 0.17 11.9 0.1 0.4 10.7 0.1 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Dehydratase_hem PF13816.6 OAG06484.1 - 4.6e-79 266.0 0.0 5.6e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 OAG06484.1 - 1e-07 32.3 0.0 3.5e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) DUF1593 PF07632.11 OAG06489.1 - 4.4e-73 245.9 1.5 4.5e-73 245.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1593) DUF2459 PF09601.10 OAG06489.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) DUF1295 PF06966.12 OAG06490.1 - 6.4e-40 137.1 8.6 7.9e-40 136.8 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OAG06490.1 - 0.12 12.9 3.7 1.1 9.8 0.1 3.1 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 OAG06491.1 - 5.4e-106 355.1 0.0 2.3e-99 333.2 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 OAG06491.1 - 2.2e-17 63.1 0.0 5.9e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.9 OAG06492.1 - 2.4e-29 101.2 0.0 4.1e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein COX6C PF02937.15 OAG06493.1 - 0.042 14.0 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc RabGAP-TBC PF00566.18 OAG06495.1 - 1.2e-32 113.3 0.1 2e-32 112.6 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Med31 PF05669.12 OAG06496.1 - 8.9e-34 115.4 1.3 1.1e-33 115.1 1.3 1.0 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 OAG06497.1 - 7.2e-42 143.4 0.5 1.8e-41 142.1 0.1 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein RecA PF00154.21 OAG06498.1 - 0.018 14.5 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Rad51 PF08423.11 OAG06498.1 - 0.033 13.5 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 Rad51 Med21 PF11221.8 OAG06498.1 - 0.12 12.7 0.3 0.12 12.7 0.3 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex RasGEF_N PF00618.20 OAG06498.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 RasGEF N-terminal motif A_deamin PF02137.18 OAG06499.1 - 2.6e-29 102.7 0.0 3.4e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NT-C2 PF10358.9 OAG06500.1 - 2.7e-33 114.7 0.1 3.7e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins AlgF PF11182.8 OAG06500.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF SLS PF14611.6 OAG06501.1 - 3.7e-32 112.0 1.9 6.3e-32 111.2 1.9 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF4777 PF16007.5 OAG06501.1 - 0.092 13.0 0.0 8.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) MMU163 PF17119.5 OAG06502.1 - 0.067 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis OCD_Mu_crystall PF02423.15 OAG06504.1 - 9.2e-17 60.9 0.0 4e-16 58.8 0.0 1.8 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAG06504.1 - 2.7e-09 37.2 0.1 9.8e-09 35.4 0.1 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG06504.1 - 0.059 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Staph_opine_DH PF10100.9 OAG06504.1 - 0.11 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase DIOX_N PF14226.6 OAG06508.1 - 3.2e-15 56.9 0.2 6.9e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG06508.1 - 6.8e-13 49.0 0.0 1.4e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG06509.1 - 1e-32 113.4 26.9 1e-32 113.4 26.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TraL PF07178.11 OAG06509.1 - 1.6 9.3 8.2 0.84 10.1 1.6 3.3 3 0 0 3 3 3 0 TraL protein NmrA PF05368.13 OAG06510.1 - 2.7e-32 112.2 0.1 4.4e-32 111.5 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG06510.1 - 4.5e-12 46.2 0.1 5.9e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG06510.1 - 1.3e-06 28.1 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG06510.1 - 0.0017 17.8 0.0 0.0048 16.3 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAG06510.1 - 0.0019 17.7 0.7 0.0033 16.9 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 OAG06510.1 - 0.012 16.2 0.2 0.026 15.1 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OAG06510.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2784 PF10861.8 OAG06510.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) TrkA_N PF02254.18 OAG06510.1 - 0.11 12.8 0.8 0.22 11.8 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Fungal_trans PF04082.18 OAG06511.1 - 9.2e-07 28.1 0.5 2.9e-06 26.5 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sushi_2 PF09014.10 OAG06511.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain NACHT PF05729.12 OAG06512.1 - 4.7e-24 85.2 0.1 8.9e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 OAG06512.1 - 2.4e-19 69.3 13.5 8.4e-10 39.1 0.8 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat HET PF06985.11 OAG06512.1 - 1.1e-15 58.3 0.5 1.1e-15 58.3 0.5 3.0 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 OAG06512.1 - 1.6e-05 25.1 0.4 0.035 14.4 0.1 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG06512.1 - 0.0053 15.8 0.7 0.024 13.6 0.7 1.9 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 OAG06512.1 - 0.0057 17.1 0.2 0.018 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 OAG06512.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG06512.1 - 0.054 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAG06512.1 - 0.096 13.1 0.0 0.41 11.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAG06512.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 OAG06512.1 - 0.14 11.3 0.1 2.4 7.3 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain IBR PF01485.21 OAG06513.1 - 0.0097 16.1 2.2 0.015 15.5 2.2 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain EAV_GP5 PF15981.5 OAG06513.1 - 0.021 15.2 0.4 0.028 14.8 0.4 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus Arrestin_C PF02752.22 OAG06514.1 - 6.9e-14 52.4 0.0 1.7e-11 44.7 0.4 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAG06514.1 - 2.6e-05 24.3 0.0 0.068 13.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF2393 PF09624.10 OAG06514.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) bZIP_1 PF00170.21 OAG06515.1 - 6.3e-06 26.2 7.7 6.3e-06 26.2 7.7 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 OAG06515.1 - 0.00048 20.2 7.2 0.0017 18.4 7.2 2.0 1 0 0 1 1 1 1 Basic region leucine zipper Mit_KHE1 PF10173.9 OAG06515.1 - 0.035 14.2 0.8 0.063 13.4 0.8 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related GvpL_GvpF PF06386.11 OAG06515.1 - 0.35 10.8 3.5 0.61 10.0 3.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Vir_act_alpha_C PF10400.9 OAG06515.1 - 0.41 11.4 5.7 0.13 13.0 2.7 1.7 2 0 0 2 2 2 0 Virulence activator alpha C-term DUF4407 PF14362.6 OAG06515.1 - 0.68 9.2 3.7 2.2 7.6 4.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Stm1_N PF09598.10 OAG06516.1 - 1.4e-15 57.9 5.7 1.4e-15 57.9 5.7 5.3 4 1 1 5 5 5 1 Stm1 HABP4_PAI-RBP1 PF04774.15 OAG06516.1 - 0.00012 22.9 6.3 0.00012 22.9 6.3 2.9 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family IBR PF01485.21 OAG06517.1 - 3.1e-14 52.9 31.6 1.2e-07 31.8 2.5 3.3 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain AA_permease_2 PF13520.6 OAG06518.1 - 3.8e-70 236.9 38.6 4.7e-70 236.6 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG06518.1 - 3.2e-20 72.2 34.6 4e-20 71.9 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease RCR PF12273.8 OAG06518.1 - 0.16 12.6 1.7 0.75 10.5 0.1 2.8 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red TPP_enzyme_N PF02776.18 OAG06520.1 - 1e-32 113.1 0.1 5.1e-32 110.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG06520.1 - 1.5e-20 73.4 0.0 2.5e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAG06520.1 - 1.5e-11 44.4 0.2 2.1e-10 40.6 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_hydro_28 PF00295.17 OAG06523.1 - 1.2e-122 409.1 24.2 1.4e-122 408.9 24.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 HAD_2 PF13419.6 OAG06524.1 - 1.1e-13 51.6 0.0 7.5e-13 49.0 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG06524.1 - 1.1e-10 42.2 0.0 4.5e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG06524.1 - 7.6e-06 25.9 0.1 1.5e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OAG06524.1 - 0.0042 17.5 0.1 0.039 14.4 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OAG06524.1 - 0.021 14.5 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase PALP PF00291.25 OAG06525.1 - 3e-62 210.7 0.6 3.8e-62 210.4 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S10 PF00450.22 OAG06526.1 - 9e-80 269.1 0.4 1.2e-79 268.7 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Pro-kuma_activ PF09286.11 OAG06527.1 - 6.3e-39 133.5 0.9 6.9e-38 130.1 0.1 2.7 4 0 0 4 4 4 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG06527.1 - 7.7e-07 28.7 0.1 1.4e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Ku_PK_bind PF08785.11 OAG06528.1 - 2.9e-32 111.3 0.0 5.3e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 OAG06528.1 - 5.8e-30 104.5 0.0 1e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Fungal_trans PF04082.18 OAG06529.1 - 3.4e-15 55.8 0.0 5.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06529.1 - 7.7e-07 29.1 10.3 7.7e-07 29.1 10.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMP PF04927.12 OAG06530.1 - 0.18 12.3 3.5 9.8 6.7 0.1 3.3 3 1 1 4 4 4 0 Seed maturation protein Macoilin PF09726.9 OAG06530.1 - 0.83 8.1 2.1 0.87 8.1 2.1 1.0 1 0 0 1 1 1 0 Macoilin family Aldo_ket_red PF00248.21 OAG06531.1 - 2.7e-63 213.9 0.0 3.4e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AIM24 PF01987.17 OAG06532.1 - 1e-51 175.7 0.1 1.3e-51 175.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ndc1_Nup PF09531.10 OAG06532.1 - 0.028 13.1 2.2 0.03 13.0 2.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAD_binding_4 PF01565.23 OAG06533.1 - 1.1e-15 57.6 0.0 2.5e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Spike_torovirin PF17072.5 OAG06534.1 - 7.7e-05 20.1 0.0 9.7e-05 19.7 0.0 1.0 1 0 0 1 1 1 1 Torovirinae spike glycoprotein Endonuc-EcoRV PF09233.11 OAG06534.1 - 0.0054 16.1 0.1 0.78 9.0 0.0 2.1 2 0 0 2 2 2 2 Restriction endonuclease EcoRV eIF-5_eIF-2B PF01873.17 OAG06535.1 - 7.7e-41 138.7 0.1 1.5e-40 137.8 0.1 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Bul1_N PF04425.12 OAG06535.1 - 0.016 14.0 1.9 0.022 13.6 1.9 1.1 1 0 0 1 1 1 0 Bul1 N terminus zf-HYPF PF07503.12 OAG06535.1 - 0.11 12.3 2.3 9.6 6.1 0.1 2.8 3 0 0 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.10 OAG06535.1 - 0.51 10.7 6.4 0.71 10.2 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain RR_TM4-6 PF06459.12 OAG06535.1 - 1.4 8.7 12.4 2.1 8.1 12.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mcm10 PF09332.11 OAG06535.1 - 7.2 5.9 15.4 18 4.6 12.7 2.2 2 0 0 2 2 2 0 Mcm10 replication factor SRR1 PF07985.12 OAG06536.1 - 2e-09 37.3 0.0 3.9e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 SRR1 Glyco_transf_28 PF03033.20 OAG06537.1 - 8.8e-15 55.0 0.0 4e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG06537.1 - 1.1e-06 27.7 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG06537.1 - 0.008 16.2 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain adh_short PF00106.25 OAG06538.1 - 3.2e-34 118.1 0.0 2.4e-33 115.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG06538.1 - 6.6e-26 91.3 0.2 1.9e-24 86.5 0.2 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG06538.1 - 0.00014 21.9 0.1 0.00025 21.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG06538.1 - 0.0032 17.0 0.2 0.025 14.0 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HAD PF12710.7 OAG06539.1 - 1.6e-18 67.7 0.0 2.7e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG06539.1 - 3.9e-14 53.5 0.1 6.6e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG06539.1 - 1.3e-08 35.0 0.1 6.7e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG06539.1 - 0.0016 18.5 0.3 0.12 12.5 0.3 3.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAG06539.1 - 0.0026 17.2 0.0 0.65 9.4 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase peroxidase PF00141.23 OAG06540.1 - 7.3e-32 110.9 0.1 1e-31 110.4 0.1 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 OAG06540.1 - 0.0075 16.2 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 Fungal peroxidase extension region BtrH_N PF14399.6 OAG06541.1 - 0.0046 17.2 0.1 0.0087 16.3 0.1 1.4 1 1 0 1 1 1 1 Butirosin biosynthesis protein H, N-terminal SNF PF00209.18 OAG06545.1 - 2.8e-75 254.0 41.2 2.8e-75 254.0 34.9 2.6 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family NYD-SP28 PF14772.6 OAG06546.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Sperm tail HET PF06985.11 OAG06547.1 - 1e-12 48.7 8.0 2e-10 41.2 0.5 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 OAG06547.1 - 2.4e-11 43.3 0.0 6.7e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAG06547.1 - 2.1e-07 31.5 0.6 8.7e-07 29.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain TPR_10 PF13374.6 OAG06547.1 - 1e-05 25.2 3.5 4.6e-05 23.2 1.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG06547.1 - 0.00074 19.8 5.5 0.0029 17.8 3.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG06547.1 - 0.0017 18.4 2.5 0.57 10.5 0.7 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG06547.1 - 0.0028 17.4 1.9 0.016 15.0 1.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG06547.1 - 0.004 17.6 0.9 0.019 15.6 0.9 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat ATPase_2 PF01637.18 OAG06547.1 - 0.0051 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_17 PF13431.6 OAG06547.1 - 0.026 14.9 0.3 0.86 10.1 0.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat BfiI_DBD PF18243.1 OAG06547.1 - 0.049 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain AAA_14 PF13173.6 OAG06547.1 - 0.12 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 OAG06547.1 - 0.25 11.5 5.6 0.19 11.9 1.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG06547.1 - 0.49 11.1 3.0 3.2 8.6 1.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Retrotran_gag_2 PF14223.6 OAG06548.1 - 5.5e-13 48.8 0.2 6.8e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Nup54 PF13874.6 OAG06549.1 - 0.032 14.3 1.3 0.049 13.7 1.3 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 AP3D1 PF06375.11 OAG06549.1 - 0.97 9.7 11.7 2.2 8.5 11.7 1.6 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 DUF1041 PF06292.17 OAG06553.1 - 0.2 12.0 1.5 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) TPR_10 PF13374.6 OAG06554.1 - 5.6e-29 99.2 0.2 3.9e-13 48.8 0.0 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG06554.1 - 2.5e-23 82.2 0.5 1.1e-13 51.2 0.1 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG06554.1 - 5.1e-09 35.5 0.5 0.0034 17.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG06554.1 - 0.00011 22.6 1.3 0.00084 19.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG06554.1 - 0.00098 19.1 0.5 1.4 9.2 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG06554.1 - 0.00099 19.7 0.0 0.005 17.5 0.0 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG06554.1 - 0.002 17.9 0.0 0.88 9.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG06554.1 - 0.025 14.9 0.1 0.82 10.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SDA1 PF05285.12 OAG06554.1 - 0.053 12.9 18.3 0.087 12.2 18.3 1.3 1 0 0 1 1 1 0 SDA1 TPR_14 PF13428.6 OAG06554.1 - 0.062 14.1 4.4 7.4 7.7 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Nop14 PF04147.12 OAG06554.1 - 0.062 11.5 19.7 0.097 10.9 19.7 1.2 1 0 0 1 1 1 0 Nop14-like family TPR_4 PF07721.14 OAG06554.1 - 0.074 13.7 0.3 7.9 7.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 OAG06554.1 - 0.19 9.8 17.9 0.34 9.0 17.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi AAA_11 PF13086.6 OAG06554.1 - 0.73 9.6 11.7 1.8 8.3 11.7 1.6 1 0 0 1 1 1 0 AAA domain DUF719 PF05334.13 OAG06554.1 - 0.99 9.6 8.6 0.7 10.1 5.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) PPP4R2 PF09184.11 OAG06554.1 - 1.8 8.1 19.3 3.8 7.0 19.3 1.5 1 0 0 1 1 1 0 PPP4R2 V_ATPase_I PF01496.19 OAG06554.1 - 1.9 6.3 14.2 3.1 5.6 14.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4045 PF13254.6 OAG06554.1 - 2.8 7.5 9.3 5 6.7 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RP-C_C PF11800.8 OAG06554.1 - 3 7.9 11.3 50 3.9 10.3 2.6 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF4637 PF15470.6 OAG06554.1 - 3.7 7.3 14.5 7.2 6.3 14.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RPN2_C PF18004.1 OAG06554.1 - 4 7.3 12.7 7.2 6.5 12.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Vfa1 PF08432.10 OAG06554.1 - 4.3 7.6 13.6 7.8 6.8 13.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TERB2 PF15101.6 OAG06554.1 - 5.2 7.1 7.6 10 6.1 7.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NOA36 PF06524.12 OAG06554.1 - 6 6.1 19.0 11 5.2 19.0 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAG06554.1 - 6.5 4.9 16.0 9.5 4.4 16.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OAG06554.1 - 6.8 5.1 14.6 12 4.3 14.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4746 PF15928.5 OAG06554.1 - 9.3 5.6 17.1 19 4.5 17.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Phosphodiest PF01663.22 OAG06555.1 - 1.5e-29 103.8 0.2 2.2e-29 103.2 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG06555.1 - 4e-05 23.2 0.0 0.0081 15.6 0.0 2.4 2 1 0 2 2 2 2 Sulfatase Methyltransf_23 PF13489.6 OAG06556.1 - 0.061 13.2 0.0 0.57 10.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain LrgB PF04172.16 OAG06557.1 - 0.013 15.0 2.3 0.025 14.1 2.3 1.5 1 1 0 1 1 1 0 LrgB-like family p450 PF00067.22 OAG06558.1 - 7.8e-67 226.0 0.0 9.1e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M10_C PF08548.11 OAG06558.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal FB_lectin PF07367.11 OAG06559.1 - 3.4e-11 43.2 0.0 7.5e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Fungal fruit body lectin HET PF06985.11 OAG06559.1 - 4.3e-10 40.1 6.3 2.4e-08 34.4 0.7 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 OAG06560.1 - 3.1e-14 53.1 0.0 9.3e-08 32.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG06560.1 - 3.7e-13 49.9 0.2 6.3e-13 49.1 0.2 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG06560.1 - 8.8e-13 48.1 0.6 9.3e-05 22.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OAG06560.1 - 1e-06 28.6 0.0 0.043 14.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat VWA_3_C PF18571.1 OAG06560.1 - 8.1e-05 22.4 2.6 1.4 8.8 0.1 3.1 3 0 0 3 3 3 3 von Willebrand factor type A C-terminal domain Ank_5 PF13857.6 OAG06560.1 - 0.0016 18.7 0.1 0.18 12.2 0.0 2.5 1 1 2 3 3 3 1 Ankyrin repeats (many copies) TbpB_B_D PF01298.18 OAG06560.1 - 0.054 13.9 0.5 0.11 12.9 0.5 1.5 1 1 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B DUF1843 PF08898.10 OAG06560.1 - 0.067 13.7 0.0 8.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Beta-lactamase PF00144.24 OAG06562.1 - 5.6e-42 144.2 1.3 7.1e-42 143.8 1.3 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 OAG06562.1 - 0.047 13.3 0.0 0.22 11.1 0.0 2.0 2 1 1 3 3 3 0 Beta-lactamase enzyme family Abhydrolase_6 PF12697.7 OAG06564.1 - 2.1e-10 41.6 0.1 2.8e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG06564.1 - 3.6e-07 29.7 0.0 7.5e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OAG06564.1 - 1.9e-05 24.4 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 OAG06564.1 - 6e-05 21.9 0.0 0.0013 17.5 0.0 2.5 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 OAG06564.1 - 0.00046 19.7 0.0 0.0012 18.4 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OAG06564.1 - 0.096 12.2 0.0 0.65 9.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family p450 PF00067.22 OAG06565.1 - 5.7e-58 196.8 0.0 8e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 OAG06566.1 - 1.5e-56 191.9 0.0 3.5e-56 190.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 OAG06566.1 - 7.8e-55 186.2 0.1 1.8e-54 185.0 0.1 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAG06566.1 - 5.5e-54 182.8 1.3 8.8e-54 182.1 0.2 2.0 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 OAG06566.1 - 6.7e-34 116.4 0.1 2e-33 114.9 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 OAG06566.1 - 2.1e-23 83.3 0.1 6e-15 55.5 0.0 2.3 1 1 1 2 2 2 2 Acyl transferase domain KAsynt_C_assoc PF16197.5 OAG06566.1 - 3.5e-21 75.8 0.0 7.2e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 OAG06566.1 - 3.4e-16 60.5 0.0 1.2e-15 58.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG06566.1 - 3.5e-14 52.9 0.2 1.4e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG06566.1 - 9.6e-11 41.5 0.3 1.1e-08 34.8 0.0 3.5 4 0 0 4 4 4 1 short chain dehydrogenase PP-binding PF00550.25 OAG06566.1 - 3.5e-07 30.5 0.0 1.7e-06 28.3 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 OAG06566.1 - 4.8e-06 26.3 0.1 1.4e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 OAG06566.1 - 0.022 14.6 0.0 0.099 12.5 0.0 2.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAD_binding_4 PF01565.23 OAG06567.1 - 1.8e-19 69.9 2.0 1.8e-19 69.9 2.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG06567.1 - 4.6e-12 45.8 1.6 1.2e-11 44.5 1.6 1.7 1 0 0 1 1 1 1 Berberine and berberine like PMR5N PF14416.6 OAG06567.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 PMR5 N terminal Domain UDPG_MGDP_dh_N PF03721.14 OAG06569.1 - 1.4e-20 73.7 1.2 5.2e-17 62.0 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 OAG06569.1 - 9.6e-20 70.6 0.0 2.3e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 OAG06569.1 - 5.6e-07 29.8 0.1 9.5e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 OAG06569.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.18 OAG06569.1 - 0.0017 18.6 0.0 0.0091 16.2 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain Rossmann-like PF10727.9 OAG06569.1 - 0.0023 17.8 0.7 0.0049 16.7 0.7 1.5 1 0 0 1 1 1 1 Rossmann-like domain F420_oxidored PF03807.17 OAG06569.1 - 0.0034 17.9 0.2 0.027 15.0 0.0 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAG06569.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG06569.1 - 0.048 13.9 0.7 0.092 13.0 0.0 1.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltr_RsmB-F PF01189.17 OAG06569.1 - 0.07 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 OAG06569.1 - 0.13 13.0 0.0 0.35 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Chitin_synth_2 PF03142.15 OAG06570.1 - 4.5e-38 131.2 4.8 1.9e-35 122.5 4.8 2.3 1 1 0 1 1 1 1 Chitin synthase Glycos_transf_2 PF00535.26 OAG06570.1 - 2.3e-07 30.8 0.0 0.0062 16.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 OAG06570.1 - 7.5e-05 22.7 6.4 7.5e-05 22.7 6.4 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG06570.1 - 0.00047 20.1 0.0 0.33 10.8 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Sarcolipin PF05366.11 OAG06570.1 - 0.22 11.2 3.1 0.51 10.1 3.1 1.6 1 0 0 1 1 1 0 Sarcolipin CPBP PF02517.16 OAG06570.1 - 2.2 8.7 6.8 0.68 10.3 0.2 2.7 3 0 0 3 3 3 0 CPBP intramembrane metalloprotease Polysacc_deac_1 PF01522.21 OAG06571.1 - 1e-22 80.3 0.0 1.6e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG06571.1 - 9.9e-16 57.9 39.9 1.1e-07 32.2 17.1 2.4 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 OAG06571.1 - 0.006 15.8 0.0 0.0098 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 OAG06571.1 - 0.07 12.8 0.1 0.13 11.9 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Amino_oxidase PF01593.24 OAG06572.1 - 1.7e-25 90.3 0.0 2.4e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG06572.1 - 1.3e-13 51.0 0.2 3.8e-13 49.5 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG06572.1 - 1.2e-10 41.5 0.0 1.2e-06 28.3 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG06572.1 - 1.6e-09 37.4 0.2 1.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG06572.1 - 4.7e-06 25.9 2.0 0.00035 19.8 2.6 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG06572.1 - 0.00014 20.8 0.7 0.0083 14.9 1.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 OAG06572.1 - 0.00077 19.5 2.0 0.042 13.8 0.3 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG06572.1 - 0.0024 17.3 4.3 0.0036 16.7 3.6 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG06572.1 - 0.0029 18.1 1.2 0.016 15.8 1.1 2.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OAG06572.1 - 0.012 14.5 0.0 0.81 8.4 0.0 2.2 2 0 0 2 2 2 0 MCRA family FAD_binding_3 PF01494.19 OAG06572.1 - 0.012 14.8 0.5 0.02 14.2 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG06572.1 - 0.019 14.2 1.5 0.037 13.3 1.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG06572.1 - 0.022 15.0 0.1 0.042 14.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 OAG06572.1 - 0.032 13.5 2.0 0.052 12.8 2.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDI PF00996.18 OAG06572.1 - 0.046 12.2 0.0 2.8 6.4 0.0 2.2 2 0 0 2 2 2 0 GDP dissociation inhibitor Thi4 PF01946.17 OAG06572.1 - 0.052 12.8 0.2 0.095 11.9 0.2 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 OAG06572.1 - 0.085 12.5 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 OAG06572.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OAG06572.1 - 0.33 10.0 1.5 0.51 9.3 0.7 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 OAG06572.1 - 0.39 10.6 1.2 0.7 9.7 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAG06572.1 - 0.47 9.5 5.0 0.23 10.5 2.6 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.25 OAG06573.1 - 1e-07 32.2 0.0 2.1e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG06573.1 - 3.3e-05 24.2 0.0 6.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG06573.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG06573.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG06573.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Hom_end PF05204.14 OAG06573.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Homing endonuclease Transp_cyt_pur PF02133.15 OAG06574.1 - 1.4e-87 294.3 33.5 1.6e-87 294.1 33.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Zn_clus PF00172.18 OAG06575.1 - 1.2e-07 31.8 10.6 1.2e-07 31.8 10.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG06575.1 - 0.0001 21.4 0.5 0.0002 20.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 OAG06576.1 - 2.7e-33 115.9 0.1 4.1e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family C12orf66_like PF09404.10 OAG06576.1 - 0.018 13.9 0.0 0.077 11.8 0.0 1.8 2 0 0 2 2 2 0 KICSTOR complex C12orf66 like Glyco_hydro_61 PF03443.14 OAG06577.1 - 5.7e-31 108.1 0.0 6.9e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 OxoGdeHyase_C PF16870.5 OAG06577.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal NGP1NT PF08153.12 OAG06578.1 - 3e-45 153.5 0.1 6.4e-45 152.5 0.1 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OAG06578.1 - 7.9e-18 64.6 0.0 1.8e-13 50.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG06578.1 - 1.1e-05 25.0 0.0 0.00027 20.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG06578.1 - 1.9e-05 24.6 0.0 0.00017 21.5 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 OAG06578.1 - 0.00037 20.0 0.0 0.3 10.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 OAG06578.1 - 0.0014 18.7 0.1 19 5.3 0.0 3.5 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.6 OAG06578.1 - 0.2 12.0 1.0 0.72 10.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain MRP-S26 PF14943.6 OAG06579.1 - 1.1 9.2 5.7 0.17 11.8 0.3 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Glyco_hydro_3_C PF01915.22 OAG06582.1 - 2.6e-49 168.0 0.1 3.8e-49 167.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG06582.1 - 4.2e-28 98.6 0.0 1.6e-27 96.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG06582.1 - 1.5e-25 89.1 0.1 2.7e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2561 PF10812.8 OAG06583.1 - 0.064 13.3 0.7 0.13 12.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) NAD_binding_1 PF00175.21 OAG06583.1 - 0.14 12.8 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain PALP PF00291.25 OAG06585.1 - 4.5e-78 262.6 0.5 6.2e-78 262.2 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OAG06585.1 - 1.1e-42 143.7 0.0 7.2e-22 77.0 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase CPSase_C PF18302.1 OAG06585.1 - 0.5 10.9 1.4 1 10.0 0.1 2.2 2 0 0 2 2 2 0 Carbamoyl phosphate synthetase C-terminal domain Nitroreductase PF00881.24 OAG06587.1 - 9.4e-27 94.1 0.0 1.2e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OAG06587.1 - 3.4e-06 26.8 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase LZ3wCH PF18517.1 OAG06587.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 Leucine zipper with capping helix domain DUF4853 PF16145.5 OAG06589.1 - 0.016 15.4 0.0 0.059 13.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) ThiS-like PF14453.6 OAG06589.1 - 0.19 11.8 0.9 0.39 10.8 0.1 2.0 2 0 0 2 2 2 0 ThiS-like ubiquitin MFS_1 PF07690.16 OAG06590.1 - 8.9e-27 93.9 29.5 5e-26 91.5 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06590.1 - 5.2e-08 32.2 5.2 5.2e-08 32.2 5.2 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 OAG06590.1 - 0.0093 14.2 0.6 0.39 8.9 0.3 2.2 2 0 0 2 2 2 2 BT1 family Aminotran_3 PF00202.21 OAG06592.1 - 3.9e-47 160.8 0.2 2.4e-45 154.9 0.2 2.1 1 1 0 1 1 1 1 Aminotransferase class-III DUF3488 PF11992.8 OAG06593.1 - 0.21 10.5 0.5 0.32 9.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) MFS_1 PF07690.16 OAG06594.1 - 2.2e-25 89.3 61.8 1.4e-21 76.8 42.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM40 PF15817.5 OAG06594.1 - 0.54 10.0 2.5 1.6 8.5 2.5 1.8 1 0 0 1 1 1 0 Transmembrane protein 40 family Glyco_hydro_43 PF04616.14 OAG06595.1 - 1.6e-34 119.6 5.0 2.4e-34 119.0 5.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG06595.1 - 8.5e-18 64.8 0.1 1.2e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain AglB_L1 PF18079.1 OAG06595.1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain zf-C2H2 PF00096.26 OAG06596.1 - 5.2e-07 29.8 9.0 0.0061 17.0 2.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG06596.1 - 0.00023 21.4 7.9 0.89 10.1 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG06596.1 - 0.0057 17.4 9.0 0.13 13.2 1.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAG06596.1 - 0.28 11.5 6.4 0.59 10.5 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Mito_carr PF00153.27 OAG06598.1 - 3.4e-71 235.2 0.6 2.8e-25 88.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 OAG06598.1 - 3.7e-19 66.8 3.5 1.1e-06 27.8 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OAG06598.1 - 4.1e-17 62.4 5.0 5.6e-08 33.1 0.7 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG06598.1 - 8.3e-15 53.4 5.4 9.4e-06 25.2 0.0 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 OAG06598.1 - 1.6e-13 50.3 0.8 3.1e-06 26.9 0.2 4.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OAG06598.1 - 1.8e-13 49.3 5.6 0.00015 21.1 0.0 4.4 4 0 0 4 4 4 3 EF hand Caleosin PF05042.13 OAG06598.1 - 0.017 15.0 0.6 8.2 6.3 0.0 2.7 2 0 0 2 2 2 0 Caleosin related protein Biotin_lipoyl PF00364.22 OAG06599.1 - 1.4e-20 72.9 0.5 3.4e-20 71.6 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAG06599.1 - 7.9e-10 38.9 0.0 2.5e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAG06599.1 - 0.0034 17.2 0.3 0.051 13.4 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like COX7a PF02238.15 OAG06600.1 - 1.1 9.8 3.5 1.1 9.8 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII AAA PF00004.29 OAG06601.1 - 1.4e-45 155.0 0.0 5.4e-41 140.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG06601.1 - 7.8e-10 38.4 0.0 2.5e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG06601.1 - 5.8e-06 26.8 0.0 7.5e-05 23.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OAG06601.1 - 1.4e-05 24.9 0.0 4.5e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 OAG06601.1 - 2.1e-05 24.7 0.0 7.2e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAG06601.1 - 0.00014 21.9 0.0 0.00056 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG06601.1 - 0.00063 20.0 0.8 0.086 13.1 0.3 3.5 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAG06601.1 - 0.001 18.4 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Bromodomain PF00439.25 OAG06601.1 - 0.0012 18.8 0.2 0.0034 17.4 0.2 1.7 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 OAG06601.1 - 0.0017 18.7 0.0 0.009 16.4 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 OAG06601.1 - 0.0082 16.7 0.0 0.0082 16.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 OAG06601.1 - 0.0092 15.4 0.8 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAG06601.1 - 0.015 15.3 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG06601.1 - 0.021 15.0 0.0 0.066 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG06601.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AFG1_ATPase PF03969.16 OAG06601.1 - 0.092 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase RuvB_N PF05496.12 OAG06601.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OAG06601.1 - 0.5 10.1 0.0 0.5 10.1 0.0 3.7 5 0 0 5 5 4 0 AAA domain AAA_23 PF13476.6 OAG06601.1 - 2.3 8.7 0.0 2.3 8.7 0.0 4.7 6 0 0 6 6 6 0 AAA domain DUF29 PF01724.16 OAG06601.1 - 2.7 8.2 10.2 2.2 8.5 1.1 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF29 HET PF06985.11 OAG06602.1 - 2e-25 89.8 0.2 2.3e-25 89.7 0.2 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Git3 PF11710.8 OAG06604.1 - 3.8e-17 62.7 18.0 3.8e-17 62.7 18.0 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 OAG06604.1 - 1.4e-08 34.7 0.4 1.4e-08 34.7 0.4 2.6 1 1 1 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF996 PF06195.13 OAG06604.1 - 5.7 7.2 13.3 0.9 9.8 2.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF996) SKA1 PF07160.12 OAG06605.1 - 0.0046 16.8 0.9 0.17 11.7 0.3 2.7 3 0 0 3 3 3 1 Spindle and kinetochore-associated protein 1 Filament PF00038.21 OAG06605.1 - 0.086 12.4 7.3 0.2 11.2 6.6 2.0 1 1 0 1 1 1 0 Intermediate filament protein ATG16 PF08614.11 OAG06605.1 - 0.15 12.3 10.9 52 4.0 10.0 3.4 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF4618 PF15397.6 OAG06605.1 - 0.15 11.4 5.9 0.27 10.6 3.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) HlyD_2 PF12700.7 OAG06605.1 - 0.29 9.8 0.6 2.6 6.7 0.3 2.0 2 0 0 2 2 2 0 HlyD family secretion protein Bacillus_HBL PF05791.11 OAG06605.1 - 0.56 10.0 3.0 0.47 10.3 1.3 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4164 PF13747.6 OAG06605.1 - 0.87 9.9 13.7 0.12 12.7 6.1 3.0 3 1 1 4 4 3 0 Domain of unknown function (DUF4164) CCDC-167 PF15188.6 OAG06605.1 - 0.97 9.8 9.6 0.21 12.0 4.1 2.8 2 1 1 3 3 2 0 Coiled-coil domain-containing protein 167 CENP-F_leu_zip PF10473.9 OAG06605.1 - 1.1 9.3 8.5 0.39 10.8 4.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 OAG06605.1 - 1.5 9.1 6.2 7 6.9 4.4 2.9 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 OAG06605.1 - 2 7.2 8.4 8 5.2 8.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 OAG06605.1 - 2.1 7.4 8.4 3.5 6.6 8.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GP20 PF06810.11 OAG06605.1 - 2.1 8.1 7.5 6.2 6.6 2.5 3.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF724 PF05266.14 OAG06605.1 - 2.2 8.1 6.4 2.1 8.2 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 OAG06605.1 - 2.5 8.6 16.5 3.8 8.0 10.1 3.8 3 1 0 3 3 3 0 Apg6 coiled-coil region DUF4407 PF14362.6 OAG06605.1 - 2.5 7.4 8.3 5.9 6.1 8.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 OAG06605.1 - 5.1 7.3 10.6 0.24 11.6 4.2 2.1 3 0 0 3 3 2 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.7 OAG06605.1 - 5.6 7.1 15.5 0.42 10.8 4.2 3.9 3 2 2 5 5 5 0 Tropomyosin like CLZ PF16526.5 OAG06605.1 - 5.9 7.3 9.3 3.8 7.9 1.9 4.0 4 2 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-H PF05837.12 OAG06605.1 - 6.7 7.2 11.4 26 5.2 7.1 3.3 3 1 0 3 3 3 0 Centromere protein H (CENP-H) Ribosomal_S5 PF00333.20 OAG06606.1 - 2.7e-27 94.5 1.0 7e-27 93.2 1.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAG06606.1 - 4.8e-23 80.4 0.0 8.7e-23 79.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 OAG06606.1 - 0.69 10.5 12.1 1.6 9.3 12.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SSF PF00474.17 OAG06607.1 - 9.8e-09 34.5 5.4 9.8e-09 34.5 5.4 2.4 2 1 0 2 2 2 1 Sodium:solute symporter family TPPK_C PF12555.8 OAG06607.1 - 0.022 14.8 0.9 0.022 14.8 0.9 4.3 4 1 1 5 5 5 0 Thiamine pyrophosphokinase C terminal PX PF00787.24 OAG06608.1 - 5.6e-27 94.0 0.0 6.7e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 PX domain EI24 PF07264.11 OAG06610.1 - 9.9e-15 55.2 3.5 1.4e-14 54.7 3.5 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Phage_holin_5_2 PF16079.5 OAG06610.1 - 0.14 12.5 0.4 0.14 12.5 0.4 2.0 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V Adaptin_N PF01602.20 OAG06612.1 - 5.6e-112 375.0 0.0 7.6e-112 374.5 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OAG06612.1 - 7e-59 198.3 1.0 1.4e-58 197.3 1.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OAG06612.1 - 1.6e-35 121.7 0.2 5.1e-35 120.1 0.2 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OAG06612.1 - 1.8e-17 63.5 2.0 7.8e-10 39.0 0.0 6.0 2 2 5 7 7 7 3 HEAT repeats Cnd1 PF12717.7 OAG06612.1 - 1.5e-07 31.6 8.4 0.063 13.3 0.2 4.6 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 OAG06612.1 - 0.13 13.0 2.4 11 7.0 0.0 4.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat HEAT PF02985.22 OAG06612.1 - 0.64 10.4 10.2 5.4 7.5 0.4 5.7 6 0 0 6 6 6 0 HEAT repeat LIAS_N PF16881.5 OAG06613.1 - 1.1e-25 90.1 0.0 2.3e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 OAG06613.1 - 7.1e-13 49.3 0.0 1.2e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF3494 PF11999.8 OAG06614.1 - 4.9e-58 196.2 25.2 4.9e-58 196.2 25.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) Glyco_hydro_43 PF04616.14 OAG06615.1 - 2.5e-103 345.4 0.3 3.9e-103 344.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG06615.1 - 1.1e-44 152.7 0.0 1.6e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 OAG06615.1 - 0.016 14.8 0.1 0.038 13.5 0.1 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain SelK_SelG PF10961.8 OAG06616.1 - 0.37 11.4 6.3 0.86 10.3 6.3 1.7 1 1 0 1 1 1 0 Selenoprotein SelK_SelG Methyltrn_RNA_3 PF02598.17 OAG06618.1 - 5.2e-89 298.5 0.0 7.7e-89 298.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methyltransferase D5_N PF08706.11 OAG06618.1 - 0.073 13.3 1.5 0.15 12.3 1.5 1.5 1 0 0 1 1 1 0 D5 N terminal like XRCC4 PF06632.12 OAG06618.1 - 0.14 11.0 10.6 0.2 10.5 10.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3636 PF12331.8 OAG06619.1 - 0.016 15.1 0.2 0.02 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) FTR1 PF03239.14 OAG06620.1 - 1.4e-82 277.3 9.2 1.7e-82 277.0 9.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Rft-1 PF04506.13 OAG06620.1 - 0.00042 19.2 2.3 0.00078 18.3 2.3 1.3 1 0 0 1 1 1 1 Rft protein FtsX PF02687.21 OAG06620.1 - 0.01 16.3 0.6 0.01 16.3 0.6 3.5 3 1 1 4 4 4 0 FtsX-like permease family DUF3149 PF11346.8 OAG06620.1 - 1 9.1 7.3 2.4 7.8 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) YitT_membrane PF02588.15 OAG06620.1 - 1.6 8.1 10.8 0.052 12.9 3.1 2.2 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF3021 PF11457.8 OAG06620.1 - 5.9 7.2 17.3 1.7 9.0 1.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Cu-oxidase_2 PF07731.14 OAG06621.1 - 3.8e-47 159.5 4.7 2e-40 137.7 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG06621.1 - 9.6e-45 151.4 3.7 1.3e-41 141.4 0.2 4.4 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG06621.1 - 4.1e-31 108.2 0.0 1.6e-26 93.3 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 OAG06621.1 - 0.00017 21.7 0.0 1.3 9.2 0.0 4.1 2 2 0 2 2 2 2 Cupredoxin-like domain DUF4026 PF13218.6 OAG06621.1 - 0.0057 15.7 0.8 2.5 7.0 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4026) Glyoxalase PF00903.25 OAG06621.1 - 0.021 15.0 0.1 0.043 14.0 0.1 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3328 PF11807.8 OAG06622.1 - 1.9e-19 70.3 1.5 9.5e-13 48.4 0.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAG06623.1 - 3.1e-27 95.8 6.6 5.7e-27 94.9 6.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PMP22_Claudin PF00822.20 OAG06624.1 - 9 6.1 9.8 1.9 8.3 1.8 2.9 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Methyltransf_2 PF00891.18 OAG06625.1 - 5.5e-31 107.5 0.0 9.4e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAG06625.1 - 0.00041 21.0 0.0 0.0014 19.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAG06625.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 OAG06625.1 - 0.0066 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG06625.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HTH_IclR PF09339.10 OAG06625.1 - 0.063 13.1 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_2 PF00891.18 OAG06626.1 - 1.6e-29 102.7 0.0 2.9e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAG06626.1 - 0.083 12.9 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 Dimerisation domain DNA_pol3_gamma3 PF12169.8 OAG06626.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III DREV PF05219.12 OAG06626.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase p450 PF00067.22 OAG06627.1 - 6e-46 157.1 0.0 7.6e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 OAG06628.1 - 6.2e-90 292.7 17.2 1.7e-10 41.3 0.0 13.2 13 0 0 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG06628.1 - 8.3e-46 154.2 6.8 2e-08 34.4 0.0 10.8 1 1 9 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG06628.1 - 6.3e-22 78.0 1.6 0.0086 15.1 0.0 9.5 3 3 7 10 10 10 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAG06628.1 - 2e-18 65.8 3.6 3.4 7.7 0.0 11.3 12 0 0 12 12 11 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 OAG06628.1 - 1.7e-17 62.7 0.0 2.5 7.9 0.0 11.0 10 0 0 10 10 10 3 Proteasome subunit A N-terminal signature NACHT PF05729.12 OAG06628.1 - 7.4e-10 39.0 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.11 OAG06628.1 - 2.2e-08 34.2 0.0 0.75 9.6 0.0 5.1 2 2 4 6 6 6 2 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 OAG06628.1 - 5.1e-06 27.0 0.3 2.2e-05 24.9 0.2 2.2 2 0 0 2 2 1 1 AAA ATPase domain SGL PF08450.12 OAG06628.1 - 6.7e-06 25.9 0.4 0.016 14.8 0.0 3.4 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 OAG06628.1 - 1.1e-05 24.2 0.4 0.012 14.2 0.0 4.2 2 2 3 5 5 5 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 OAG06628.1 - 1.3e-05 24.4 0.0 1.2 8.1 0.0 3.8 2 2 2 4 4 4 2 Coatomer WD associated region TruB_C PF09142.11 OAG06628.1 - 1.8e-05 24.4 2.8 11 5.9 0.0 6.7 7 0 0 7 7 7 0 tRNA Pseudouridine synthase II, C terminal IKI3 PF04762.12 OAG06628.1 - 1.8e-05 23.0 2.1 0.047 11.7 0.0 3.5 4 1 0 4 4 4 2 IKI3 family PALB2_WD40 PF16756.5 OAG06628.1 - 3.8e-05 22.8 6.3 7.8 5.3 0.1 6.3 4 3 3 7 7 7 0 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 OAG06628.1 - 0.00054 19.4 9.7 2.5 7.4 0.1 6.6 1 1 5 6 6 6 1 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.6 OAG06628.1 - 0.0024 18.2 0.1 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRF-TF PF00319.18 OAG06628.1 - 0.0084 15.6 0.2 48 3.6 0.0 5.6 8 0 0 8 8 8 0 SRF-type transcription factor (DNA-binding and dimerisation domain) AAA_18 PF13238.6 OAG06628.1 - 0.016 15.7 1.0 0.12 13.0 0.1 3.0 3 1 0 3 3 2 0 AAA domain SMP_2 PF10144.9 OAG06628.1 - 0.029 14.0 0.1 15 5.2 0.0 3.9 3 2 1 4 4 4 0 Bacterial virulence factor haemolysin AAA PF00004.29 OAG06628.1 - 0.03 14.7 0.0 0.28 11.6 0.0 2.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) WD40_like PF17005.5 OAG06628.1 - 0.031 13.6 0.0 0.75 9.1 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain VCH_CASS14 PF18315.1 OAG06628.1 - 0.044 13.8 0.0 12 6.1 0.0 4.0 3 1 0 3 3 3 0 Integron cassette protein VCH_CASS1 chain NB-ARC PF00931.22 OAG06628.1 - 0.092 11.9 0.0 0.25 10.5 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 OAG06628.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 OAG06628.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain HeLo PF14479.6 OAG06629.1 - 4.4e-45 154.0 0.7 5.6e-45 153.7 0.7 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation Phage_lysozyme PF00959.19 OAG06629.1 - 0.027 14.9 0.0 0.047 14.2 0.0 1.3 1 0 0 1 1 1 0 Phage lysozyme HET PF06985.11 OAG06630.1 - 1.7e-34 119.3 0.2 3.5e-34 118.3 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-H2C2_2 PF13465.6 OAG06630.1 - 0.14 12.6 0.3 0.44 11.1 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger double domain Trns_repr_metal PF02583.17 OAG06631.1 - 0.062 13.7 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor Vac7 PF12751.7 OAG06631.1 - 0.1 12.0 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 IBR PF01485.21 OAG06632.1 - 8.8e-16 57.9 33.7 1.9e-09 37.6 6.4 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 OAG06632.1 - 2.6 8.3 23.3 0.49 10.6 1.5 3.7 3 1 0 3 3 3 0 AN1-like Zinc finger Amidohydro_2 PF04909.14 OAG06634.1 - 9.3e-24 84.7 0.2 1.3e-23 84.2 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase AIP3 PF03915.13 OAG06634.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 PfkB PF00294.24 OAG06635.1 - 3.4e-16 59.4 0.0 6.6e-15 55.2 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Ank_2 PF12796.7 OAG06636.1 - 5.1e-45 152.0 15.7 3.2e-10 40.5 0.0 7.5 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG06636.1 - 1.4e-38 130.8 9.4 3e-08 34.0 0.0 9.8 7 2 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG06636.1 - 5e-32 106.3 9.7 6.2e-06 26.2 0.0 13.3 14 0 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 OAG06636.1 - 1.2e-26 92.4 8.0 2.5e-09 37.2 0.1 7.7 7 2 1 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG06636.1 - 1.1e-22 79.4 15.1 2.7e-05 24.4 0.1 12.0 14 0 0 14 14 14 7 Ankyrin repeat NACHT PF05729.12 OAG06636.1 - 0.00016 21.7 0.0 0.00041 20.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG06636.1 - 0.0032 17.7 0.0 0.0096 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG06636.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Neprosin PF03080.15 OAG06637.1 - 2.1e-48 164.6 10.0 2.7e-48 164.3 10.0 1.1 1 0 0 1 1 1 1 Neprosin S-antigen PF05756.11 OAG06637.1 - 0.8 10.1 5.8 1.9 8.9 0.5 3.0 3 0 0 3 3 3 0 S-antigen protein Fructosamin_kin PF03881.14 OAG06638.1 - 2.2e-73 246.9 0.0 2.6e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG06638.1 - 0.00063 19.7 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG06638.1 - 0.0037 16.2 0.0 0.0055 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) MFS_1 PF07690.16 OAG06640.1 - 5.4e-25 88.1 53.2 2.5e-24 85.9 43.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAG06641.1 - 1.9e-08 34.3 10.6 1.9e-08 34.3 10.6 3.8 3 2 1 4 4 4 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 OAG06641.1 - 1.2e-05 25.1 9.7 1.2e-05 25.1 9.7 4.7 4 1 0 4 4 4 1 PHD-finger KIX_2 PF16987.5 OAG06641.1 - 0.18 11.8 1.8 0.42 10.6 0.5 2.2 2 1 0 2 2 2 0 KIX domain L31 PF09784.9 OAG06642.1 - 0.054 13.9 0.0 0.21 12.0 0.0 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 CorA PF01544.18 OAG06643.1 - 2.4e-11 43.5 0.9 3.7e-11 42.9 0.3 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein BacA PF02673.18 OAG06643.1 - 0.016 14.9 0.1 0.039 13.7 0.3 1.5 2 0 0 2 2 2 0 Bacitracin resistance protein BacA DUF2207 PF09972.9 OAG06643.1 - 0.025 13.4 0.1 0.14 10.9 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SieB PF14163.6 OAG06643.1 - 0.13 11.7 0.6 0.21 11.1 0.6 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF3792 PF12670.7 OAG06643.1 - 0.46 10.7 4.2 0.79 9.9 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) 2OG-FeII_Oxy PF03171.20 OAG06644.1 - 1.6e-15 57.4 0.0 3.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG06644.1 - 5.5e-11 43.2 0.0 1.1e-10 42.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 OAG06645.1 - 9.4e-34 116.9 26.8 9.4e-34 116.9 26.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily His_Phos_2 PF00328.22 OAG06646.1 - 1.5e-26 93.6 0.0 1.9e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Hanta_G1 PF01567.16 OAG06646.1 - 0.039 12.7 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 PDE6_gamma PF04868.12 OAG06646.1 - 0.11 12.8 0.0 0.84 9.9 0.0 2.5 2 1 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit HlyIII PF03006.20 OAG06647.1 - 1.3e-44 152.6 15.2 1.5e-44 152.3 15.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related SnAC PF14619.6 OAG06647.1 - 0.014 16.0 0.0 0.021 15.4 0.0 1.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex DUF962 PF06127.11 OAG06647.1 - 0.026 14.6 0.0 0.11 12.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF962) EamA PF00892.20 OAG06647.1 - 0.15 12.2 5.1 0.52 10.5 1.3 2.6 2 0 0 2 2 2 0 EamA-like transporter family Patatin PF01734.22 OAG06649.1 - 1.2e-24 87.7 0.0 1.8e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Beta-lactamase PF00144.24 OAG06649.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase PH PF00169.29 OAG06651.1 - 4.4e-06 27.2 0.1 1.6e-05 25.4 0.1 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 OAG06651.1 - 1.5e-05 25.3 0.1 0.00081 19.7 0.1 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain MlaE PF02405.16 OAG06653.1 - 0.1 12.2 1.7 0.17 11.6 1.7 1.3 1 0 0 1 1 1 0 Permease MlaE MFS_1 PF07690.16 OAG06655.1 - 7e-36 123.9 23.2 9.9e-36 123.4 23.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG06655.1 - 3.5e-05 23.3 3.9 3.5e-05 23.3 3.9 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB NAD_binding_4 PF07993.12 OAG06656.1 - 3.2e-37 128.1 0.0 5e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG06656.1 - 1.5e-36 125.9 0.0 2.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAG06656.1 - 1.9e-07 30.8 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG06656.1 - 5e-05 23.3 0.1 0.00017 21.5 0.0 1.9 2 0 0 2 2 2 1 KR domain PP-binding PF00550.25 OAG06656.1 - 0.0001 22.6 0.1 0.00097 19.4 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site FMO-like PF00743.19 OAG06658.1 - 1.7e-43 148.9 0.0 4.5e-23 81.5 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG06658.1 - 2.7e-15 56.4 2.8 1.6e-11 44.0 0.4 3.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG06658.1 - 1.7e-13 50.4 0.0 4.6e-12 45.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG06658.1 - 2.5e-06 26.9 0.1 0.00018 20.7 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG06658.1 - 2.5e-05 24.0 0.0 0.53 9.8 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG06658.1 - 0.00034 20.8 0.0 0.00082 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG06658.1 - 0.00044 20.3 0.0 0.56 10.2 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG06658.1 - 0.0015 17.8 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Semialdhyde_dh PF01118.24 OAG06658.1 - 0.008 16.6 0.0 0.81 10.1 0.0 2.8 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG06658.1 - 0.25 10.0 0.4 3.1 6.4 0.1 2.3 2 1 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 OAG06659.1 - 6.3e-32 110.9 41.4 2e-29 102.7 20.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FtsH_ext PF06480.15 OAG06659.1 - 0.086 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 FtsH Extracellular Peptidase_M19 PF01244.21 OAG06660.1 - 4.7e-68 229.7 0.0 5.7e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.16 OAG06662.1 - 4e-25 88.5 54.1 3.2e-20 72.4 34.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06662.1 - 3.8e-14 52.4 25.1 2e-13 50.1 25.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter YqhR PF11085.8 OAG06662.1 - 0.97 9.3 7.1 0.25 11.3 1.4 2.7 3 0 0 3 3 3 0 Conserved membrane protein YqhR WD40 PF00400.32 OAG06663.1 - 5.1e-19 68.3 9.3 0.00017 22.3 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG06663.1 - 6.9e-17 61.5 0.0 0.00011 22.5 0.0 5.1 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OAG06663.1 - 0.00016 20.9 0.0 0.74 8.8 0.0 3.1 2 1 1 3 3 3 3 Coatomer WD associated region eIF2A PF08662.11 OAG06663.1 - 0.00018 21.4 0.5 0.084 12.7 0.0 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAG06663.1 - 0.0076 15.3 0.1 5.9 5.7 0.0 3.6 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAG06663.1 - 0.093 12.7 6.5 3.5 7.7 0.3 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RWD PF05773.22 OAG06664.1 - 0.046 14.0 0.1 0.38 11.0 0.1 2.2 1 1 0 1 1 1 0 RWD domain DASH_Dad2 PF08654.10 OAG06664.1 - 0.056 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 Epimerase PF01370.21 OAG06665.1 - 5.6e-13 48.9 0.0 1.5e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG06665.1 - 2.5e-06 27.5 0.8 1.3e-05 25.2 0.6 2.2 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG06665.1 - 1.6e-05 24.1 0.0 4.8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG06665.1 - 5.5e-05 22.5 0.0 0.019 14.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 OAG06665.1 - 0.0014 18.2 0.0 0.0041 16.7 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 OAG06665.1 - 0.0038 16.4 0.0 0.53 9.3 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain AA_permease_2 PF13520.6 OAG06669.1 - 1.1e-56 192.5 42.8 1.5e-56 192.1 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG06669.1 - 1.1e-24 86.9 31.8 1.5e-24 86.4 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease 60KD_IMP PF02096.20 OAG06669.1 - 0.014 15.3 2.5 0.014 15.3 2.5 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein HET PF06985.11 OAG06670.1 - 3.8e-12 46.8 2.7 4.6e-09 36.8 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) LapA_dom PF06305.11 OAG06672.1 - 0.017 14.9 0.1 0.027 14.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 OAG06672.1 - 0.17 11.3 0.1 0.3 10.5 0.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HET PF06985.11 OAG06673.1 - 1.7e-31 109.5 0.0 2.1e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG06674.1 - 1.3e-11 45.0 6.7 3.8e-10 40.3 1.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Allene_ox_cyc PF06351.11 OAG06674.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Allene oxide cyclase Glyco_hydro_92 PF07971.12 OAG06675.1 - 4.8e-150 500.5 0.4 5.7e-150 500.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG06675.1 - 9.7e-60 202.4 1.1 1.6e-59 201.7 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Zn_clus PF00172.18 OAG06676.1 - 4.6e-08 33.1 11.5 1.1e-07 31.8 11.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG06676.1 - 1.4e-07 30.9 0.0 2.4e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_9 PF13901.6 OAG06676.1 - 0.0012 18.8 0.8 1.8 8.5 0.7 2.5 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon FMO-like PF00743.19 OAG06677.1 - 1.8e-18 66.3 0.0 1.6e-17 63.1 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG06677.1 - 2.5e-15 56.5 0.0 2.6e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG06677.1 - 1.8e-13 50.4 0.0 2.1e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG06677.1 - 1.7e-08 34.0 0.0 0.00013 21.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG06677.1 - 9e-06 25.8 0.0 2.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG06677.1 - 9.4e-05 22.1 0.2 0.031 13.8 0.0 3.0 1 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG06677.1 - 0.00014 21.9 0.3 0.036 14.0 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG06677.1 - 0.00027 20.4 0.0 0.00072 19.0 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAG06677.1 - 0.00029 21.1 0.0 0.0009 19.5 0.0 1.9 1 0 0 1 1 1 1 TrkA-N domain HI0933_like PF03486.14 OAG06677.1 - 0.0003 19.6 0.0 0.0006 18.6 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG06677.1 - 0.00031 19.9 0.0 0.00055 19.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG06677.1 - 0.00066 18.9 1.3 0.0019 17.4 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG06677.1 - 0.0033 16.8 0.2 0.0086 15.4 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAG06677.1 - 0.0038 17.7 0.1 0.031 14.8 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG06677.1 - 0.013 14.8 0.0 0.09 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 OAG06677.1 - 0.044 12.8 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 OAG06677.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 OAG06677.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 OAG06677.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain UCH PF00443.29 OAG06678.1 - 1.5e-44 152.5 0.0 3.5e-44 151.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG06678.1 - 5.5e-07 29.5 0.0 0.013 15.1 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF572 PF04502.13 OAG06678.1 - 1.3 8.6 5.7 2.7 7.5 5.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C3HC4 PF00097.25 OAG06679.1 - 1.5e-07 31.2 5.4 2.5e-07 30.4 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG06679.1 - 1.9e-06 27.7 4.3 4.4e-06 26.6 4.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG06679.1 - 4.6e-06 26.4 5.0 2.7e-05 23.9 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG06679.1 - 8e-06 25.6 4.6 1.6e-05 24.6 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG06679.1 - 1.8e-05 24.6 4.5 5.1e-05 23.1 4.5 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG06679.1 - 3e-05 24.2 5.6 0.00011 22.5 5.6 1.9 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAG06679.1 - 5e-05 23.4 2.6 0.00013 22.1 2.6 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAG06679.1 - 0.33 11.3 4.6 1.2 9.5 4.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAG06679.1 - 2.1 8.3 12.3 34 4.4 11.7 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DLH PF01738.18 OAG06680.1 - 2.2e-28 99.3 0.0 2.7e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 OAG06680.1 - 0.056 13.0 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 OAG06680.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase adh_short_C2 PF13561.6 OAG06681.1 - 2.6e-55 187.5 0.0 3.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG06681.1 - 1.2e-44 152.1 0.1 1.4e-44 151.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG06681.1 - 4.7e-11 42.9 0.1 6.7e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 OAG06682.1 - 7.7e-40 136.9 0.8 9.7e-40 136.5 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06682.1 - 8.1e-06 25.9 10.0 1.7e-05 24.8 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5594 PF18057.1 OAG06682.1 - 0.091 12.6 0.1 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5594) CENP-O PF09496.10 OAG06684.1 - 6.3e-58 196.2 0.0 9.8e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acatn PF13000.7 OAG06685.1 - 9.5e-161 536.0 17.2 9.8e-81 271.9 6.7 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 OAG06685.1 - 0.0034 16.3 6.5 0.0034 16.3 6.5 2.2 2 1 0 2 2 2 1 MFS_1 like family AhpC-TSA PF00578.21 OAG06686.1 - 4.3e-32 110.6 0.0 6.1e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 OAG06686.1 - 1.1e-14 54.0 0.1 2.2e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 OAG06686.1 - 1.3e-14 54.2 0.0 1.7e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin ImpE PF07024.13 OAG06688.1 - 0.052 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 ImpE protein Tannase PF07519.11 OAG06689.1 - 3.4e-94 316.4 0.0 5.3e-93 312.5 0.0 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG06689.1 - 6.6e-05 22.5 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG06689.1 - 0.0019 17.5 0.0 0.0072 15.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG06689.1 - 0.0025 17.5 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG06690.1 - 3.7e-86 290.0 0.0 4.6e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG06690.1 - 4e-08 33.4 0.0 1.6e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold CCDC71L PF15374.6 OAG06692.1 - 7.4 5.7 19.8 15 4.7 19.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L PAP1 PF08601.10 OAG06693.1 - 6.3e-08 32.8 4.8 4e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 OAG06693.1 - 1.7e-07 31.2 12.1 3.5e-07 30.2 12.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 OAG06693.1 - 0.0019 18.0 4.2 0.0028 17.4 4.2 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 OAG06693.1 - 0.035 14.6 11.8 0.06 13.9 11.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF1929 PF09118.11 OAG06693.1 - 0.047 14.0 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) GvpL_GvpF PF06386.11 OAG06693.1 - 0.11 12.4 6.3 0.18 11.7 6.3 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V_ATPase_I PF01496.19 OAG06693.1 - 0.23 9.3 0.2 0.26 9.1 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 OAG06693.1 - 0.26 11.4 10.3 0.48 10.5 10.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 OAG06693.1 - 0.96 9.6 16.6 0.096 12.8 11.1 2.1 2 1 1 3 3 3 0 Basic region leucine zipper Phosducin PF02114.16 OAG06694.1 - 2.6e-12 46.2 0.0 3.6e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Phosducin Helo_like_N PF17111.5 OAG06696.1 - 5e-05 22.8 0.4 0.00012 21.5 0.4 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF4404 PF14357.6 OAG06696.1 - 0.033 14.8 1.4 0.074 13.7 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF4503 PF14951.6 OAG06697.1 - 0.12 10.8 0.0 0.13 10.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) ADP_ribosyl_GH PF03747.14 OAG06699.1 - 6.1e-65 219.8 1.2 7e-65 219.6 1.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase FAD_binding_4 PF01565.23 OAG06700.1 - 7.8e-33 113.1 6.4 1.3e-32 112.4 6.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG06700.1 - 5.4e-08 32.8 0.4 1.2e-07 31.7 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Slx4 PF09494.10 OAG06700.1 - 0.089 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease XPG_N PF00752.17 OAG06701.1 - 1.6e-36 124.8 0.1 1.6e-35 121.6 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 OAG06701.1 - 1.2e-24 86.4 0.0 3.4e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 OAG06701.1 - 3.6e-05 24.3 0.1 0.00019 22.0 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 OAG06701.1 - 0.018 15.6 0.0 0.045 14.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 OAG06701.1 - 0.045 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family PTCB-BRCT PF12738.7 OAG06703.1 - 0.00046 20.1 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 OAG06703.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CDP-OH_P_transf PF01066.21 OAG06704.1 - 4.3e-16 59.4 0.1 4.3e-16 59.4 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.13 OAG06705.1 - 3.3e-41 139.6 1.7 9.7e-29 99.6 0.1 2.5 3 0 0 3 3 3 2 NIPSNAP SIP1 PF04938.12 OAG06707.1 - 7.2e-10 38.9 0.1 7.2e-09 35.7 0.0 2.5 3 0 0 3 3 3 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) UBM PF14377.6 OAG06707.1 - 1.5e-07 30.6 1.3 1.5e-07 30.6 1.3 2.6 1 1 1 2 2 2 1 Ubiquitin binding region zf-C3H1 PF10650.9 OAG06707.1 - 0.2 11.4 0.3 0.41 10.4 0.3 1.6 1 0 0 1 1 1 0 Putative zinc-finger domain CDH-cyt PF16010.5 OAG06708.1 - 5.7e-54 182.6 0.7 1.8e-52 177.7 0.0 2.8 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 OAG06708.1 - 3.4e-29 102.2 0.1 1.8e-28 99.8 0.1 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG06708.1 - 3.5e-22 79.5 0.1 8.2e-22 78.3 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG06708.1 - 2.4e-08 33.5 5.0 4.1e-06 26.1 1.9 2.9 3 1 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 OAG06708.1 - 1e-05 24.5 3.6 1.2e-05 24.2 1.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG06708.1 - 1e-05 25.1 4.2 1.1e-05 25.0 2.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OAG06708.1 - 1.1e-05 25.2 1.6 0.0022 17.6 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG06708.1 - 1.4e-05 24.5 0.3 0.00017 21.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG06708.1 - 9.3e-05 21.7 0.3 0.00017 20.8 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAG06708.1 - 0.00023 20.6 1.0 0.001 18.4 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAG06708.1 - 0.00067 19.8 0.8 0.0019 18.4 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG06708.1 - 0.00079 18.6 0.8 0.0018 17.4 0.8 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG06708.1 - 0.0032 16.7 0.2 0.0067 15.7 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OAG06708.1 - 0.021 15.4 2.3 0.071 13.7 1.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YL1_C PF08265.11 OAG06708.1 - 0.023 14.5 0.5 5 7.0 0.0 2.8 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Trp_halogenase PF04820.14 OAG06708.1 - 0.036 12.9 2.4 0.045 12.6 1.5 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG06708.1 - 0.068 12.4 2.3 0.19 10.9 2.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG06708.1 - 0.18 11.0 2.8 0.23 10.8 0.3 2.3 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Amnionless PF14828.6 OAG06709.1 - 0.00028 19.9 0.2 0.0003 19.8 0.2 1.0 1 0 0 1 1 1 1 Amnionless RIFIN PF02009.16 OAG06709.1 - 0.00042 20.3 2.9 0.00046 20.2 2.9 1.0 1 0 0 1 1 1 1 Rifin SKG6 PF08693.10 OAG06709.1 - 0.0017 17.7 7.7 0.0024 17.3 7.7 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OAG06709.1 - 0.0023 18.8 1.9 0.0025 18.7 0.9 1.6 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 OAG06709.1 - 0.0049 16.5 0.7 0.0055 16.3 0.7 1.0 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 OAG06709.1 - 0.015 14.1 0.1 0.015 14.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Protocadherin PF08374.11 OAG06709.1 - 0.017 15.1 0.6 0.019 14.9 0.6 1.1 1 0 0 1 1 1 0 Protocadherin ECSCR PF15820.5 OAG06709.1 - 0.02 14.7 0.3 0.025 14.4 0.3 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4668 PF15701.5 OAG06709.1 - 0.024 14.5 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Rax2 PF12768.7 OAG06709.1 - 0.03 13.8 0.4 0.032 13.7 0.4 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Orf78 PF06024.12 OAG06709.1 - 0.042 14.1 0.1 0.05 13.9 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) BatD PF13584.6 OAG06709.1 - 0.063 12.1 0.0 0.067 12.0 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF2561 PF10812.8 OAG06709.1 - 0.066 13.2 1.6 0.082 12.9 1.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) Podoplanin PF05808.11 OAG06709.1 - 0.1 12.7 1.2 0.12 12.5 1.2 1.2 1 0 0 1 1 1 0 Podoplanin Mid2 PF04478.12 OAG06709.1 - 0.11 12.3 0.8 0.12 12.2 0.8 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF5305 PF17231.2 OAG06709.1 - 0.11 11.9 0.2 0.12 11.8 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4448 PF14610.6 OAG06709.1 - 0.11 12.2 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) L1R_F9L PF02442.17 OAG06709.1 - 0.12 12.2 1.4 0.15 11.9 1.4 1.2 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses DUF5385 PF17359.2 OAG06709.1 - 0.14 11.7 0.3 0.14 11.7 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Herpes_gE PF02480.16 OAG06709.1 - 0.16 10.7 0.3 0.16 10.7 0.3 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Myc_target_1 PF15179.6 OAG06709.1 - 0.19 11.6 1.8 0.24 11.3 1.6 1.3 1 1 0 1 1 1 0 Myc target protein 1 Syndecan PF01034.20 OAG06709.1 - 0.19 11.6 5.6 0.3 11.0 5.6 1.3 1 0 0 1 1 1 0 Syndecan domain CYYR1 PF10873.8 OAG06709.1 - 0.2 12.1 0.4 0.25 11.8 0.4 1.2 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Vpu PF00558.19 OAG06709.1 - 0.22 11.3 1.4 0.34 10.7 1.4 1.4 1 0 0 1 1 1 0 Vpu protein UPF0258 PF06789.12 OAG06709.1 - 0.46 10.6 1.5 0.56 10.3 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Baculo_11_kDa PF06143.11 OAG06709.1 - 0.57 9.8 3.1 0.41 10.3 1.2 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family Glycophorin_A PF01102.18 OAG06709.1 - 0.58 10.4 4.2 0.71 10.1 4.2 1.3 1 1 0 1 1 1 0 Glycophorin A Herpes_US9 PF06072.11 OAG06709.1 - 0.8 9.6 3.4 0.55 10.1 1.0 1.9 1 1 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Insulin_TMD PF17870.1 OAG06709.1 - 2.5 8.3 8.3 5.3 7.2 8.3 1.5 1 1 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4381 PF14316.6 OAG06709.1 - 5.8 7.1 7.1 6.5 7.0 2.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) EzrA PF06160.12 OAG06709.1 - 7.8 4.5 5.9 13 3.8 5.9 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF676 PF05057.14 OAG06710.1 - 0.00011 21.8 0.0 0.00023 20.7 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG06710.1 - 0.00041 21.0 0.0 0.00053 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG06710.1 - 0.00099 18.4 0.1 0.0047 16.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG06710.1 - 0.002 17.8 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 OAG06710.1 - 0.0034 16.6 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Cutinase PF01083.22 OAG06710.1 - 0.1 12.6 0.0 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 Cutinase Ser_hydrolase PF06821.13 OAG06710.1 - 0.16 11.8 0.0 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase B5 PF03484.15 OAG06711.1 - 0.088 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 tRNA synthetase B5 domain PLDc_N PF13396.6 OAG06712.1 - 4.6e-13 48.9 3.8 4.6e-13 48.9 3.8 1.5 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal Glucos_trans_II PF14264.6 OAG06712.1 - 0.0077 15.6 0.6 0.0086 15.5 0.6 1.1 1 0 0 1 1 1 1 Glucosyl transferase GtrII Pox_A14 PF05767.12 OAG06712.1 - 0.015 15.4 0.8 0.019 15.1 0.1 1.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Tetraspanin PF00335.20 OAG06712.1 - 0.036 13.8 1.5 0.04 13.6 1.5 1.0 1 0 0 1 1 1 0 Tetraspanin family TMEM251 PF15190.6 OAG06712.1 - 0.071 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 251 FAD_binding_3 PF01494.19 OAG06713.1 - 5.6e-30 104.8 0.0 8.2e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG06713.1 - 3.8e-07 30.0 0.1 0.004 16.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG06713.1 - 3.6e-06 26.4 0.0 0.064 12.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG06713.1 - 0.00026 21.1 0.0 0.00073 19.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG06713.1 - 0.00089 18.2 0.6 0.31 9.8 0.0 3.0 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 OAG06713.1 - 0.0026 18.3 0.0 0.045 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG06713.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Ank_2 PF12796.7 OAG06714.1 - 4.8e-42 142.4 0.0 1.3e-12 48.2 0.0 8.2 7 1 1 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG06714.1 - 4.8e-32 106.4 3.1 0.00076 19.7 0.0 12.7 13 0 0 13 13 13 5 Ankyrin repeat Ank_4 PF13637.6 OAG06714.1 - 5.6e-29 100.1 0.9 4e-05 24.1 0.0 10.1 9 2 2 11 11 11 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG06714.1 - 3.6e-27 94.1 0.3 0.0055 17.0 0.0 10.3 10 1 1 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 OAG06714.1 - 4.6e-26 90.1 5.5 0.00057 20.2 0.0 10.8 12 0 0 12 12 12 6 Ankyrin repeat DUF2025 PF09634.10 OAG06714.1 - 0.098 12.7 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) Kelch_5 PF13854.6 OAG06715.1 - 1.7e-30 104.5 8.6 7.8e-10 38.5 0.2 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OAG06715.1 - 7.3e-29 99.5 15.5 4.8e-06 26.5 1.3 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG06715.1 - 1.5e-28 98.5 14.5 1.6e-05 25.0 0.3 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG06715.1 - 9.5e-27 92.4 13.0 5.5e-11 42.4 1.3 6.5 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OAG06715.1 - 6.3e-24 83.3 10.3 2.6e-11 42.9 0.8 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OAG06715.1 - 4.1e-18 64.6 14.0 5.8e-10 38.7 0.8 6.2 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.14 OAG06715.1 - 0.028 13.4 0.0 0.83 8.6 0.0 2.6 2 0 0 2 2 2 0 Recombination activating protein 2 Raptor_N PF14538.6 OAG06716.1 - 1.2e-65 219.9 0.0 2.4e-65 219.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain ANAPC4_WD40 PF12894.7 OAG06716.1 - 3.1e-06 27.4 0.6 1.1 9.6 0.4 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG06716.1 - 5.1e-06 27.1 8.3 0.051 14.5 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAG06716.1 - 2.5e-05 24.2 0.2 0.011 15.7 0.0 2.9 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 OAG06716.1 - 0.0087 16.2 7.5 4.1 7.9 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 OAG06716.1 - 0.05 13.6 0.1 0.46 10.5 0.2 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 OAG06716.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain F-box-like PF12937.7 OAG06717.1 - 8.4e-09 35.2 1.8 3e-08 33.4 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG06717.1 - 0.00042 20.1 0.0 0.0017 18.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain Helicase_Sgs1 PF11408.8 OAG06717.1 - 0.045 13.8 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Sgs1 RecQ helicase LRR_4 PF12799.7 OAG06717.1 - 1.6 9.3 4.2 1.6e+02 2.9 0.0 4.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) HSP70 PF00012.20 OAG06718.1 - 1e-75 255.1 1.0 1e-75 255.1 1.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG06718.1 - 1.3e-09 37.3 0.2 2.2e-09 36.6 0.2 1.4 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 OAG06718.1 - 0.023 13.7 0.2 2 7.3 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; FAM176 PF14851.6 OAG06718.1 - 1.3 8.6 5.4 0.72 9.5 1.7 2.0 2 0 0 2 2 2 0 FAM176 family Rrp40_N PF18311.1 OAG06719.1 - 3.3e-16 59.0 2.3 6.8e-16 57.9 2.3 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 OAG06719.1 - 9.6e-14 51.5 1.4 1.8e-13 50.6 1.4 1.5 1 0 0 1 1 1 1 KH domain tRNA-synt_2 PF00152.20 OAG06720.1 - 7.2e-71 238.8 0.0 9.4e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG06720.1 - 2.7e-05 24.0 0.1 4.6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG06720.1 - 0.13 11.8 0.3 5.1 6.5 0.2 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Ribophorin_II PF05817.14 OAG06720.1 - 0.14 10.7 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Med3 PF11593.8 OAG06720.1 - 0.98 8.5 3.5 1.4 8.1 3.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PTR2 PF00854.21 OAG06721.1 - 9.9e-80 268.3 3.7 1.5e-79 267.7 3.7 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG06721.1 - 3.4e-09 36.1 24.3 3.3e-07 29.6 25.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06721.1 - 0.0058 15.5 17.8 0.05 12.5 0.2 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter AAA PF00004.29 OAG06722.1 - 2.2e-19 70.2 0.0 2.2e-18 66.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG06722.1 - 0.0012 19.3 0.0 0.0037 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG06722.1 - 0.0029 17.9 0.2 0.015 15.6 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG06722.1 - 0.0057 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAG06722.1 - 0.0074 16.8 0.6 0.16 12.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 OAG06722.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 OAG06722.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Hydin_ADK PF17213.3 OAG06722.1 - 0.5 10.6 0.0 0.5 10.6 0.0 4.0 3 1 0 3 3 3 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 OAG06723.1 - 0.018 14.9 0.9 0.053 13.4 0.1 2.1 2 0 0 2 2 2 0 NACHT domain YabA PF06156.13 OAG06723.1 - 0.16 12.6 0.0 0.59 10.8 0.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA MFS_1 PF07690.16 OAG06724.1 - 3.5e-45 154.5 24.1 3.5e-45 154.5 24.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06724.1 - 3.5e-14 52.5 4.3 3.5e-14 52.5 4.3 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter DUF389 PF04087.14 OAG06724.1 - 0.0037 17.3 2.6 1.9 8.5 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF389) DUF4179 PF13786.6 OAG06724.1 - 0.3 11.6 1.4 19 5.8 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) OATP PF03137.20 OAG06724.1 - 2.8 6.1 10.4 0.41 8.9 5.7 1.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SCO1-SenC PF02630.14 OAG06725.1 - 5e-48 162.4 0.0 8.4e-48 161.7 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 OAG06725.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OAG06725.1 - 0.064 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like HD_3 PF13023.6 OAG06725.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 HD domain OPT PF03169.15 OAG06728.1 - 1.9e-85 287.7 45.8 2.4e-85 287.4 45.8 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein QCR10 PF09796.9 OAG06728.1 - 7.3 6.7 7.7 0.8 9.8 0.8 3.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) PKcGMP_CC PF16808.5 OAG06729.1 - 0.0016 18.3 10.0 0.25 11.2 0.0 4.0 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase CENP-F_leu_zip PF10473.9 OAG06729.1 - 0.003 17.6 0.3 0.003 17.6 0.3 3.8 3 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 OAG06729.1 - 0.018 15.1 14.9 0.72 10.0 0.2 5.2 4 2 2 6 6 5 0 bZIP transcription factor bZIP_2 PF07716.15 OAG06729.1 - 0.091 12.9 0.9 0.091 12.9 0.9 4.6 5 0 0 5 5 5 0 Basic region leucine zipper LRS4 PF10422.9 OAG06729.1 - 0.12 11.9 1.1 0.51 9.9 0.0 2.4 2 1 1 3 3 3 0 Monopolin complex subunit LRS4 NPV_P10 PF05531.12 OAG06729.1 - 0.3 11.6 1.6 16 6.0 0.1 3.4 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein ASD2 PF08687.11 OAG06729.1 - 0.46 10.0 8.7 0.078 12.5 2.3 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 HalX PF08663.10 OAG06729.1 - 0.73 10.2 0.1 0.73 10.2 0.1 4.1 5 1 0 5 5 4 0 HalX domain NFACT-C PF11923.8 OAG06729.1 - 0.83 9.6 4.2 2.4 8.1 0.2 2.8 2 1 1 3 3 3 0 NFACT protein C-terminal domain UPF0242 PF06785.11 OAG06729.1 - 0.84 9.7 9.8 3.6 7.6 3.1 2.8 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 OAG06729.1 - 2.2 9.2 13.9 33 5.5 0.6 4.0 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain TMF_DNA_bd PF12329.8 OAG06729.1 - 4.8 7.2 19.1 1.2 9.2 0.3 5.0 6 0 0 6 6 6 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 OAG06729.1 - 5.7 7.2 21.2 8.6 6.6 1.1 4.5 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DMPK_coil PF08826.10 OAG06729.1 - 9.3 6.5 17.5 2.3 8.4 0.2 4.0 4 0 0 4 4 4 0 DMPK coiled coil domain like Dynamin_N PF00350.23 OAG06730.1 - 5e-08 33.2 0.0 1.9e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Dynamin family AAA_15 PF13175.6 OAG06730.1 - 0.00017 21.4 0.1 0.00017 21.4 0.1 2.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 OAG06730.1 - 0.00071 20.0 0.8 0.0029 18.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain IIGP PF05049.13 OAG06730.1 - 0.002 17.3 0.0 0.0071 15.4 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 OAG06730.1 - 0.0028 17.7 0.0 0.13 12.3 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase eIF3_p135 PF12807.7 OAG06730.1 - 0.021 14.8 0.3 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 DFRP_C PF16543.5 OAG06730.1 - 0.063 13.8 0.0 0.33 11.5 0.0 2.3 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 AAA_22 PF13401.6 OAG06730.1 - 0.1 12.9 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PEP-utilisers_N PF05524.13 OAG06730.1 - 3.9 7.7 9.2 4 7.6 0.1 4.3 4 1 1 5 5 5 0 PEP-utilising enzyme, N-terminal Aldo_ket_red PF00248.21 OAG06733.1 - 2e-45 155.3 0.0 2.3e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 OAG06734.1 - 2.2e-35 122.2 64.1 5e-34 117.8 46.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.6 OAG06734.1 - 0.17 12.2 0.1 0.17 12.2 0.1 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) MFS_1_like PF12832.7 OAG06734.1 - 0.27 10.1 24.5 0.036 12.9 9.4 2.3 2 0 0 2 2 2 0 MFS_1 like family HET PF06985.11 OAG06735.1 - 1.8e-22 80.2 0.1 3.6e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FBPase PF00316.20 OAG06736.1 - 2.8e-24 85.6 0.0 4.1e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 OAG06736.1 - 0.051 13.1 1.0 0.2 11.1 0.1 2.0 2 0 0 2 2 2 0 Inositol monophosphatase family Trypan_PARP PF05887.11 OAG06737.1 - 0.77 9.7 28.7 25 4.9 24.4 3.3 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3446 PF11928.8 OAG06738.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.0 1 1 1 2 2 2 0 Early growth response N-terminal domain DHHC PF01529.20 OAG06739.1 - 4.1e-35 120.8 3.9 4.1e-35 120.8 3.9 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase SET PF00856.28 OAG06740.1 - 7.3e-16 59.0 0.4 7.3e-16 59.0 0.4 3.5 3 1 0 3 3 3 1 SET domain AWS PF17907.1 OAG06740.1 - 3.4e-07 30.2 5.8 3.4e-07 30.2 5.8 2.3 2 0 0 2 2 2 1 AWS domain BSP_II PF05432.11 OAG06740.1 - 2.1 8.0 14.8 0.33 10.6 5.9 2.9 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) PFU PF09070.11 OAG06741.1 - 0.0057 16.9 0.2 0.016 15.5 0.1 1.7 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) zf-His_Me_endon PF05551.11 OAG06742.1 - 3.6e-10 40.2 2.0 7.9e-10 39.0 2.0 1.5 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease Lactonase PF10282.9 OAG06743.1 - 6.6e-65 219.6 0.3 7.3e-65 219.5 0.3 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Hydrolase_6 PF13344.6 OAG06744.1 - 2e-24 85.6 0.0 9.1e-24 83.5 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG06744.1 - 4.6e-17 61.9 0.1 2.3e-16 59.6 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG06744.1 - 0.00079 19.8 0.1 2.8 8.2 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 OAG06745.1 - 6.5e-11 41.8 0.2 1.4e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06745.1 - 1.2e-06 28.6 10.5 2.2e-06 27.7 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZZ PF00569.17 OAG06746.1 - 4.6e-12 45.6 6.4 7.7e-12 44.8 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 OAG06746.1 - 8.8e-10 38.9 3.2 0.00037 20.9 0.2 4.4 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 OAG06746.1 - 4.2e-08 32.2 15.7 0.0011 18.4 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 OAG06746.1 - 9e-08 31.5 8.7 0.00065 19.4 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OAG06746.1 - 6.7e-07 29.1 1.8 0.18 11.6 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair DUF4685 PF15737.5 OAG06746.1 - 0.17 12.3 0.7 0.42 11.0 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) EF-hand_5 PF13202.6 OAG06746.1 - 0.81 9.3 10.3 0.54 9.8 0.1 3.8 4 0 0 4 4 4 0 EF hand adh_short_C2 PF13561.6 OAG06747.1 - 2.8e-59 200.5 0.2 3.2e-59 200.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG06747.1 - 7e-51 172.5 1.2 9e-51 172.1 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG06747.1 - 5.4e-15 55.8 0.3 7.2e-15 55.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG06747.1 - 0.024 14.1 0.1 0.036 13.5 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amidase PF01425.21 OAG06748.1 - 3.5e-98 329.5 0.0 6.3e-98 328.7 0.0 1.4 1 1 0 1 1 1 1 Amidase TIP39 PF14980.6 OAG06748.1 - 0.075 12.9 0.0 0.29 11.1 0.1 1.9 2 0 0 2 2 2 0 TIP39 peptide Abhydrolase_6 PF12697.7 OAG06749.1 - 0.065 13.8 14.6 0.2 12.2 14.6 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.32 OAG06750.1 - 5.4e-19 68.2 24.5 1.9e-05 25.4 0.5 9.6 8 0 0 8 8 8 4 WD domain, G-beta repeat CPSF_A PF03178.15 OAG06750.1 - 0.054 12.8 0.0 14 4.9 0.0 2.9 3 0 0 3 3 3 0 CPSF A subunit region ANAPC4_WD40 PF12894.7 OAG06750.1 - 0.11 12.8 0.0 10 6.5 0.0 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAG06750.1 - 1.9 9.1 4.0 13 6.5 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain Polysacc_synt_4 PF04669.13 OAG06751.1 - 2.9e-21 75.9 0.2 1.4e-19 70.4 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 OAG06751.1 - 5.4 6.8 7.3 0.32 10.7 0.5 2.3 3 0 0 3 3 3 0 Acetylcholinesterase tetramerisation domain ABC_membrane PF00664.23 OAG06752.1 - 2.4e-87 293.1 31.3 8.7e-45 153.5 11.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG06752.1 - 5.4e-63 211.6 0.3 1.3e-30 106.7 0.1 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OAG06752.1 - 1.2e-12 47.7 5.8 3.2e-07 30.0 0.4 5.1 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG06752.1 - 2.9e-09 37.3 2.6 0.0083 16.4 0.0 4.4 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OAG06752.1 - 4.4e-09 35.9 0.5 0.0028 17.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 OAG06752.1 - 1.9e-08 33.5 1.9 0.035 12.9 0.1 4.5 5 0 0 5 5 5 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 OAG06752.1 - 3.2e-08 34.2 0.6 0.0069 16.8 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG06752.1 - 9.1e-06 25.7 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 OAG06752.1 - 1e-05 25.2 0.3 0.068 12.7 0.0 3.4 3 1 0 4 4 4 2 AAA domain AAA_15 PF13175.6 OAG06752.1 - 1.1e-05 25.4 0.0 0.062 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG06752.1 - 3.5e-05 23.8 1.2 0.17 11.7 0.1 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 OAG06752.1 - 0.00022 21.8 0.0 0.47 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAG06752.1 - 0.00063 20.3 0.1 0.62 10.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 OAG06752.1 - 0.00098 19.1 0.1 1 9.4 0.0 3.2 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAG06752.1 - 0.0012 18.6 2.1 2.6 7.7 0.1 3.9 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.6 OAG06752.1 - 0.0014 18.8 0.0 1.9 8.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 OAG06752.1 - 0.0023 18.0 2.0 0.18 11.9 0.4 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 OAG06752.1 - 0.0031 17.6 0.1 2.8 8.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 OAG06752.1 - 0.0049 16.6 0.1 2.7 7.6 0.0 3.4 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 OAG06752.1 - 0.0056 16.6 0.0 3.4 7.5 0.1 2.8 3 0 0 3 3 2 1 Adenylylsulphate kinase DUF3987 PF13148.6 OAG06752.1 - 0.0072 15.4 0.0 3.8 6.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Zeta_toxin PF06414.12 OAG06752.1 - 0.0076 15.5 0.0 3.9 6.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ATPase PF06745.13 OAG06752.1 - 0.011 15.1 3.9 1.6 8.0 0.0 3.2 4 0 0 4 4 3 0 KaiC FtsK_SpoIIIE PF01580.18 OAG06752.1 - 0.018 14.4 0.1 3.9 6.8 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 OAG06752.1 - 0.02 14.8 0.1 9.9 6.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain CobA_CobO_BtuR PF02572.15 OAG06752.1 - 0.027 14.7 0.0 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP IstB_IS21 PF01695.17 OAG06752.1 - 0.027 14.2 0.3 5.1 6.8 0.0 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 OAG06752.1 - 0.031 14.5 1.8 4.5 7.6 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Sigma54_activat PF00158.26 OAG06752.1 - 0.037 13.7 0.0 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OAG06752.1 - 0.041 14.3 0.9 8.8 6.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase PRK PF00485.18 OAG06752.1 - 0.075 12.8 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.17 OAG06752.1 - 0.08 12.6 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.17 OAG06752.1 - 0.095 12.5 0.2 15 5.2 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 OAG06752.1 - 0.11 12.5 0.1 8.6 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 OAG06752.1 - 0.14 11.3 0.1 9.2 5.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 OAG06752.1 - 0.16 11.1 0.0 8.4 5.4 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 OAG06752.1 - 0.16 11.3 0.0 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAG06752.1 - 0.22 11.2 0.8 11 5.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAG06752.1 - 0.24 10.6 2.7 11 5.1 0.6 3.1 3 1 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) DUF4191 PF13829.6 OAG06752.1 - 1.8 7.9 5.1 0.33 10.3 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Lipase_3 PF01764.25 OAG06753.1 - 2.9e-06 27.2 0.0 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 OAG06753.1 - 0.0029 17.6 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 OAG06753.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG06753.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-primase PF09329.11 OAG06755.1 - 0.12 12.2 3.4 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 Primase zinc finger ATP-synt_J PF04911.12 OAG06756.1 - 4.9e-25 86.8 1.1 5.5e-25 86.7 1.1 1.1 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.11 OAG06757.1 - 9.1e-51 171.9 1.6 1.3e-50 171.3 1.6 1.2 1 0 0 1 1 1 1 Spc19 Med4 PF10018.9 OAG06757.1 - 0.014 15.1 1.6 0.071 12.8 0.0 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Pkinase PF00069.25 OAG06758.1 - 2.3e-26 92.8 0.0 2.8e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG06758.1 - 6.2e-14 51.9 0.0 8.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG06758.1 - 4.2e-09 35.7 0.0 6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG06758.1 - 0.00017 21.6 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Rsm22 PF09243.10 OAG06759.1 - 3.3e-28 98.7 0.0 1.5e-25 90.0 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Band_3_cyto PF07565.13 OAG06759.1 - 0.015 15.1 0.3 0.027 14.3 0.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain F-box-like PF12937.7 OAG06760.1 - 1.2e-08 34.7 0.5 3.9e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG06760.1 - 0.082 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 F-box domain Acetyltransf_10 PF13673.7 OAG06761.1 - 1.5e-09 37.9 0.0 2.4e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG06761.1 - 2.8e-09 37.3 0.0 3.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG06761.1 - 5.4e-07 29.8 0.0 7.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAG06761.1 - 0.00013 22.1 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG06761.1 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltr_2 PF13718.6 OAG06761.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 HET PF06985.11 OAG06763.1 - 8.3e-25 87.8 0.0 1.9e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 OAG06763.1 - 1.7e-21 76.8 0.0 2.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG06763.1 - 3.3e-14 52.8 0.0 5.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG06764.1 - 3.4e-23 82.3 0.0 4.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG06764.1 - 2.9e-13 49.7 0.0 4.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AnmK PF03702.14 OAG06765.1 - 9.4e-87 291.5 0.0 1.1e-86 291.2 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Fungal_trans PF04082.18 OAG06766.1 - 8.1e-16 57.8 0.4 1.2e-15 57.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06766.1 - 0.0041 17.2 8.8 0.0069 16.5 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOTI PF17079.5 OAG06766.1 - 0.08 13.4 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 Male-specific protein scotti Sugar_tr PF00083.24 OAG06767.1 - 1.6e-74 251.4 18.6 2e-74 251.1 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG06767.1 - 1.9e-24 86.2 33.8 2.9e-20 72.5 21.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3902 PF13042.6 OAG06767.1 - 0.13 11.9 5.5 0.29 10.7 5.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3902) DUF1129 PF06570.11 OAG06767.1 - 0.32 10.4 3.7 2.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) BPL_LplA_LipB PF03099.19 OAG06768.1 - 1.9e-09 37.5 0.0 2.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rpp20 PF12328.8 OAG06769.1 - 2.4e-36 124.7 4.9 2.4e-36 124.7 4.9 1.7 2 1 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 OAG06769.1 - 2.7e-07 30.3 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Alba zf-RING_2 PF13639.6 OAG06770.1 - 0.0012 19.2 7.2 0.0012 19.2 7.2 5.0 4 1 2 6 6 6 1 Ring finger domain FMO-like PF00743.19 OAG06771.1 - 1.9e-12 46.4 0.1 2.3e-11 42.8 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG06771.1 - 5.6e-11 42.2 1.2 2e-08 33.9 0.7 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG06771.1 - 1.8e-09 37.2 0.0 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG06771.1 - 4.9e-09 36.3 0.9 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG06771.1 - 9.5e-08 31.6 0.2 2.8e-05 23.4 0.0 3.3 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG06771.1 - 0.0001 22.3 0.1 0.0035 17.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG06771.1 - 0.0003 20.5 0.0 0.0041 16.7 0.0 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG06771.1 - 0.0047 16.1 0.1 2.3 7.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAG06771.1 - 0.0094 15.2 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG06771.1 - 0.026 13.9 0.1 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG06771.1 - 0.11 11.7 0.0 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 OAG06771.1 - 0.15 10.7 0.1 0.24 10.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein TRI12 PF06609.13 OAG06772.1 - 1.1e-46 159.5 18.3 1.5e-46 159.0 18.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG06772.1 - 3.9e-14 52.3 53.9 6e-14 51.7 50.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06772.1 - 6.6e-09 35.1 11.8 6.6e-09 35.1 11.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter EHN PF06441.12 OAG06773.1 - 1.8e-30 105.5 0.4 3.3e-30 104.7 0.4 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG06773.1 - 1.6e-09 37.8 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG06773.1 - 0.00064 20.4 0.4 0.0022 18.6 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_28 PF00295.17 OAG06774.1 - 9.5e-34 116.9 9.4 1.4e-33 116.3 9.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Asn_synthase PF00733.21 OAG06775.1 - 9.3e-74 249.2 0.0 1.3e-73 248.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 OAG06775.1 - 1.7e-35 121.6 0.0 5.8e-35 119.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAG06775.1 - 1.3e-32 112.9 0.0 3e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAG06775.1 - 1.7e-06 27.6 0.0 3.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein DUF1933 PF09147.10 OAG06775.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) SLT PF01464.20 OAG06776.1 - 5.3e-09 35.8 0.0 1.1e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Transglycosylase SLT domain Peroxidase_2 PF01328.17 OAG06777.1 - 6.9e-46 157.1 0.0 8.4e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Membr_traf_MHD PF10540.9 OAG06778.1 - 0.051 13.8 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain Acetyltransf_2 PF00797.17 OAG06779.1 - 3.8e-35 121.8 0.0 8.4e-35 120.7 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase Peptidase_C71 PF12386.8 OAG06779.1 - 0.093 12.4 0.1 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei Transglut_core PF01841.19 OAG06779.1 - 0.18 12.2 0.7 1.8 9.0 0.0 2.9 3 1 1 4 4 4 0 Transglutaminase-like superfamily RMI1_C PF16099.5 OAG06783.1 - 0.038 13.8 0.1 0.096 12.5 0.1 1.6 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Stn1 PF10451.9 OAG06783.1 - 0.13 11.2 1.6 0.22 10.4 0.1 1.9 2 0 0 2 2 2 0 Telomere regulation protein Stn1 DUF4164 PF13747.6 OAG06783.1 - 3 8.2 13.3 0.63 10.3 8.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Mitochondr_Som1 PF11093.8 OAG06784.1 - 0.00016 21.6 0.3 0.00034 20.5 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial export protein Som1 PEX-1N PF09262.11 OAG06784.1 - 0.19 12.1 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal zf-HIT PF04438.16 OAG06786.1 - 0.13 12.1 1.2 0.22 11.4 1.2 1.3 1 0 0 1 1 1 0 HIT zinc finger Raffinose_syn PF05691.12 OAG06787.1 - 2.4e-51 174.4 4.3 2.1e-49 168.0 4.3 2.4 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 DUF3648 PF12364.8 OAG06787.1 - 0.0099 16.1 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3648) tRNA-synt_1b PF00579.25 OAG06788.1 - 3.5e-68 230.1 0.0 5e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 OAG06788.1 - 1.1e-32 112.3 0.0 3.6e-32 110.7 0.0 1.8 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain tRNA-synt_2 PF00152.20 OAG06789.1 - 3.2e-91 305.7 0.0 4.4e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OAG06789.1 - 0.0073 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 OAG06789.1 - 0.022 14.3 0.1 0.092 12.2 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 OAG06789.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Pil1 PF13805.6 OAG06790.1 - 1.5e-127 424.6 0.3 1.9e-127 424.3 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 OAG06790.1 - 0.036 13.5 1.7 0.057 12.8 1.0 1.5 1 1 0 1 1 1 0 FAM92 protein Octopine_DH PF02317.17 OAG06790.1 - 0.14 12.2 0.1 0.49 10.5 0.1 1.9 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain ABC_membrane_2 PF06472.15 OAG06790.1 - 0.2 11.0 0.1 0.33 10.3 0.1 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 Peptidase_C14 PF00656.22 OAG06791.1 - 0.0001 22.3 0.0 0.0049 16.9 0.0 2.4 1 1 0 2 2 2 2 Caspase domain SGL PF08450.12 OAG06792.1 - 3.5e-65 220.0 0.2 4.2e-65 219.8 0.2 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 OAG06792.1 - 0.004 17.1 0.0 0.31 10.9 0.0 2.2 1 1 1 2 2 2 2 Esterase-like activity of phytase DUF3297 PF11730.8 OAG06792.1 - 0.15 12.0 0.2 7 6.6 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3297) Tom37 PF10568.9 OAG06793.1 - 6e-35 120.3 0.3 9.3e-35 119.7 0.3 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 OAG06793.1 - 1.2e-14 53.9 0.0 2.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG06793.1 - 1.6e-09 38.4 0.0 2.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 OAG06793.1 - 1.6e-07 31.2 0.0 5.7e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG06793.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Saw1 PF11561.8 OAG06794.1 - 0.05 13.1 0.1 3.9 6.9 0.1 2.3 2 0 0 2 2 2 0 Single strand annealing-weakened 1 NAD_binding_11 PF14833.6 OAG06795.1 - 2.7e-38 130.9 0.0 5.8e-26 91.1 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 OAG06795.1 - 6.6e-32 110.9 0.3 1.1e-31 110.1 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAG06795.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAG06795.1 - 0.074 13.6 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PIP5K PF01504.18 OAG06796.1 - 6.4e-39 133.8 4.1 2.3e-31 109.0 0.3 2.7 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OAG06796.1 - 2.9e-30 105.4 0.0 5.3e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OAG06796.1 - 2.2e-14 53.3 6.8 2.2e-14 53.3 6.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 OAG06796.1 - 1.7 8.6 6.4 0.84 9.6 3.8 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3336 PF11815.8 OAG06798.1 - 4.4e-36 123.6 0.1 7.7e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG06798.1 - 1.2e-20 74.6 0.0 3e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PilS PF08805.11 OAG06798.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 PilS N terminal AT_hook PF02178.19 OAG06799.1 - 0.0078 16.0 3.9 0.043 13.7 2.1 3.3 2 0 0 2 2 2 1 AT hook motif Na_H_Exchanger PF00999.21 OAG06800.1 - 5.2e-59 200.0 44.8 7.3e-59 199.5 44.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_92 PF07971.12 OAG06801.1 - 2.8e-134 448.5 1.0 3.3e-134 448.3 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG06801.1 - 1.3e-45 156.1 2.4 1.9e-45 155.6 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DNA_binding_1 PF01035.20 OAG06802.1 - 3.7e-25 87.9 0.0 6.9e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF1989 PF09347.10 OAG06803.1 - 5.9e-31 107.3 0.0 2.8e-21 75.9 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF1989) Adipokin_hormo PF06377.11 OAG06804.1 - 7.6e-07 29.4 4.9 8.9 6.8 0.0 7.0 7 0 0 7 7 7 4 Adipokinetic hormone Peptidase_M22 PF00814.25 OAG06805.1 - 6.8e-41 140.8 0.1 3.6e-22 79.4 0.1 3.0 1 1 1 2 2 2 2 Glycoprotease family DUF3336 PF11815.8 OAG06806.1 - 1.1e-48 164.4 5.7 1.7e-48 163.8 5.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG06806.1 - 6.7e-18 65.6 0.6 1.9e-17 64.1 0.1 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C2H2 PF00096.26 OAG06807.1 - 3.5e-29 99.6 56.9 5.2e-05 23.5 0.3 10.6 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG06807.1 - 7.9e-26 88.5 46.9 0.0011 19.6 0.2 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG06807.1 - 1.2e-15 57.1 49.2 7.8e-05 22.9 1.6 10.2 11 0 0 11 11 11 5 Zinc-finger double domain zf-met PF12874.7 OAG06807.1 - 1.2e-06 28.7 13.7 0.31 11.5 0.1 8.3 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 OAG06807.1 - 0.00012 22.7 19.1 0.0024 18.5 3.4 5.3 5 1 0 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 OAG06807.1 - 0.00042 20.5 24.5 2.2 8.6 1.0 9.2 11 1 0 11 11 10 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OAG06807.1 - 0.0015 18.7 18.2 0.092 13.0 3.7 4.4 3 1 2 5 5 5 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 OAG06807.1 - 0.012 15.8 20.0 2.2 8.4 0.8 5.9 4 2 2 7 7 7 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 OAG06807.1 - 0.051 13.3 16.2 0.42 10.4 0.0 6.0 6 0 0 6 6 6 0 zinc-finger C2H2-type GCN5L1 PF06320.13 OAG06807.1 - 0.069 13.3 0.1 47 4.2 0.0 3.3 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) FOXP-CC PF16159.5 OAG06807.1 - 0.21 12.2 38.0 0.89 10.2 0.2 8.3 6 2 3 9 9 9 0 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 OAG06807.1 - 6.4 6.7 7.0 2.3 8.1 0.1 3.7 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) RNA_pol_Rpb6 PF01192.22 OAG06808.1 - 2e-15 56.4 0.1 3.5e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 OAG06808.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Esterase PF00756.20 OAG06809.1 - 1.3e-54 185.5 0.0 1.5e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OAG06809.1 - 9.6e-06 25.2 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAG06809.1 - 0.00091 18.8 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 OAG06809.1 - 0.0022 17.3 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAG06809.1 - 0.006 15.5 0.0 0.01 14.8 0.0 1.3 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 OAG06809.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 OAG06809.1 - 0.031 13.8 0.1 0.085 12.4 0.1 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family PGAP1 PF07819.13 OAG06809.1 - 0.052 13.3 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 OAG06809.1 - 0.19 10.7 0.0 0.41 9.6 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase Xpo1 PF08389.12 OAG06810.1 - 1.3e-34 119.4 2.2 5.3e-33 114.2 0.1 4.1 5 0 0 5 5 5 1 Exportin 1-like protein PDEase_I PF00233.19 OAG06812.1 - 1.1e-66 225.0 0.0 1.5e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FAD_binding_4 PF01565.23 OAG06813.1 - 1e-12 48.0 3.5 2e-12 47.0 3.5 1.5 1 0 0 1 1 1 1 FAD binding domain Myb_DNA-binding PF00249.31 OAG06815.1 - 7e-07 29.3 0.6 1.5e-06 28.3 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG06815.1 - 0.00043 20.5 3.5 0.00057 20.1 1.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain SIR2 PF02146.17 OAG06817.1 - 7.2e-34 117.2 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Glyco_hydro_3_C PF01915.22 OAG06818.1 - 5.4e-50 170.2 0.0 1.5e-49 168.7 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG06818.1 - 1.9e-42 145.8 0.0 2.9e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG06818.1 - 2.5e-23 82.0 0.2 5.4e-23 80.9 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Vps62 PF06101.11 OAG06819.1 - 1.2e-13 50.2 6.9 4.5e-13 48.4 6.3 1.9 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Zn_clus PF00172.18 OAG06821.1 - 0.00011 22.3 11.0 0.00021 21.4 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG06822.1 - 9.9e-33 113.5 54.7 2e-24 86.2 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06822.1 - 1.4e-06 27.5 32.9 0.00099 18.1 0.3 4.1 2 2 1 4 4 4 3 Sugar (and other) transporter PMT PF02366.18 OAG06823.1 - 1.6e-81 273.6 14.8 2.7e-81 272.8 14.8 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAG06823.1 - 3e-67 226.1 14.1 3e-67 226.1 14.1 1.7 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAG06823.1 - 1.4e-46 158.7 0.0 2.7e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 MIR domain DUF2530 PF10745.9 OAG06823.1 - 0.051 13.8 2.1 0.48 10.7 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) PRP21_like_P PF12230.8 OAG06824.1 - 7.9e-49 166.5 0.1 1.8e-48 165.3 0.1 1.6 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 OAG06824.1 - 2.9e-24 84.8 1.1 3.8e-14 52.4 0.3 2.5 2 0 0 2 2 2 2 Surp module zf-C2HC_2 PF13913.6 OAG06824.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-WRNIP1_ubi PF18279.1 OAG06824.1 - 0.00061 20.2 0.2 0.0015 19.0 0.2 1.7 1 0 0 1 1 1 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf_UBZ PF18439.1 OAG06824.1 - 0.0007 19.1 0.7 0.0017 17.9 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Complex1_LYR PF05347.15 OAG06825.1 - 2e-19 69.4 4.2 3e-19 68.8 4.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG06825.1 - 3.9e-07 30.7 2.1 4.1e-07 30.6 2.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OAG06825.1 - 0.00057 20.4 0.4 0.00067 20.2 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 OAG06825.1 - 0.046 13.7 0.1 0.071 13.1 0.1 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III F_bP_aldolase PF01116.20 OAG06827.1 - 5.2e-84 282.0 0.3 5.8e-84 281.9 0.3 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MutS_V PF00488.21 OAG06828.1 - 3.1e-66 223.0 0.2 6.3e-66 222.0 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG06828.1 - 2.6e-42 145.2 0.1 6.5e-42 143.9 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAG06828.1 - 9.6e-32 109.6 0.1 4.8e-31 107.3 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAG06828.1 - 3.4e-14 53.3 0.2 1.7e-13 51.0 0.0 2.3 3 0 0 3 3 2 1 MutS domain II MutS_IV PF05190.18 OAG06828.1 - 2.8e-12 46.8 0.2 9.2e-12 45.2 0.2 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 OAG06828.1 - 0.013 16.0 0.2 0.013 16.0 0.2 2.2 2 1 0 2 2 2 0 AAA domain DHC_N2 PF08393.13 OAG06828.1 - 0.021 14.0 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 AAA_29 PF13555.6 OAG06828.1 - 0.07 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG06828.1 - 0.079 12.8 1.5 0.11 12.3 0.2 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 OAG06828.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Shugoshin_C PF07557.11 OAG06828.1 - 0.11 12.4 0.9 0.3 10.9 0.9 1.8 1 0 0 1 1 1 0 Shugoshin C terminus Mac PF12464.8 OAG06829.1 - 2e-13 50.3 0.0 6.3e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Maltose acetyltransferase rve_3 PF13683.6 OAG06829.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Pescadillo_N PF06732.11 OAG06831.1 - 1.2e-124 415.3 0.0 1.2e-124 415.3 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 OAG06831.1 - 5.7e-06 26.6 0.0 1.9e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG06831.1 - 0.013 15.7 0.2 0.049 13.9 0.2 2.0 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain BRCT PF00533.26 OAG06831.1 - 0.015 15.6 0.0 0.055 13.9 0.0 2.0 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.13 OAG06832.1 - 5e-118 394.5 27.3 5.7e-118 394.3 27.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U ORC6 PF05460.13 OAG06833.1 - 0.35 10.1 1.8 0.4 9.9 1.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) His_Phos_1 PF00300.22 OAG06834.1 - 2.5e-09 37.1 0.0 1.2e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Afi1 PF07792.12 OAG06835.1 - 1.5e-45 154.9 0.9 2.8e-45 154.0 0.9 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 OAG06835.1 - 6.4e-37 126.0 0.0 1.3e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 OAG06835.1 - 7.4e-07 28.2 0.0 0.19 10.4 0.0 4.1 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 OAG06835.1 - 0.013 15.1 0.0 0.061 12.9 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF1168 PF06658.12 OAG06835.1 - 1.8 8.4 11.2 0.34 10.7 6.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Cwf_Cwc_15 PF04889.12 OAG06835.1 - 2.2 8.0 13.7 0.11 12.2 8.0 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EF-hand_6 PF13405.6 OAG06836.1 - 6.8e-12 44.3 0.1 9.9e-05 22.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAG06836.1 - 7.1e-09 34.6 1.9 0.0014 18.1 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OAG06836.1 - 9.3e-07 29.2 0.2 3.6e-06 27.3 0.2 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAG06836.1 - 0.00025 20.4 4.3 0.27 10.8 1.5 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 OAG06836.1 - 0.00038 20.7 0.0 0.37 11.2 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OAG06836.1 - 0.0049 16.7 0.3 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair DUF1932 PF09130.11 OAG06838.1 - 9.4e-23 80.0 0.0 2.8e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 OAG06838.1 - 2.6e-08 34.2 0.0 4.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAG06838.1 - 7.3e-07 29.7 0.1 1.4e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG06838.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAG06838.1 - 0.0041 16.7 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 OAG06838.1 - 0.021 14.7 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 OAG06838.1 - 0.04 13.8 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 OAG06838.1 - 0.081 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase zf-HC5HC2H_2 PF13832.6 OAG06839.1 - 2.5e-31 108.1 11.1 2.5e-31 108.1 11.1 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 OAG06839.1 - 5.8e-31 108.0 0.0 1.4e-30 106.7 0.0 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 OAG06839.1 - 1.6e-25 89.1 18.9 1.6e-25 89.1 10.0 2.5 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD_2 PF13831.6 OAG06839.1 - 1.7e-14 53.1 1.8 1.7e-14 53.1 1.8 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 OAG06839.1 - 1.5e-08 34.4 9.3 1.5e-08 34.4 9.3 2.8 2 0 0 2 2 2 1 PHD-finger RRM_1 PF00076.22 OAG06840.1 - 4e-20 71.4 0.0 5.8e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG06840.1 - 0.0012 18.5 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3431 PF11913.8 OAG06841.1 - 1.9e-88 295.8 1.1 2.6e-88 295.4 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DNA_binding_1 PF01035.20 OAG06843.1 - 2.4e-28 98.1 0.0 3.2e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain TPR_14 PF13428.6 OAG06844.1 - 6.1 8.0 10.7 0.55 11.2 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Beta-lactamase PF00144.24 OAG06845.1 - 6.4e-41 140.7 2.6 1.9e-40 139.1 2.6 1.6 1 1 0 1 1 1 1 Beta-lactamase Cellulase PF00150.18 OAG06846.1 - 5.1e-35 121.3 8.6 9.3e-35 120.4 8.6 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 OAG06846.1 - 5e-21 74.6 4.4 7.8e-17 61.2 3.1 3.2 2 1 0 2 2 2 2 Carbohydrate binding domain X2 CBM_1 PF00734.18 OAG06846.1 - 8.1e-12 44.9 13.7 2.5e-11 43.3 13.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Lustrin_cystein PF14625.6 OAG06846.1 - 0.072 13.5 3.2 0.16 12.4 3.2 1.5 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Kei1 PF08552.11 OAG06846.1 - 0.1 12.4 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 AF-4 PF05110.13 OAG06846.1 - 2.3 6.2 8.6 3.2 5.7 8.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SecE PF00584.20 OAG06848.1 - 1.8e-14 53.4 0.1 2.3e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TMEM51 PF15345.6 OAG06848.1 - 0.19 11.5 0.1 0.24 11.2 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 WD40 PF00400.32 OAG06849.1 - 4.4e-21 74.8 22.5 3.5e-05 24.5 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.6 OAG06849.1 - 0.0021 18.5 1.9 2.1 9.0 0.1 3.4 3 0 0 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.16 OAG06849.1 - 0.019 13.5 2.7 0.33 9.4 0.0 3.3 3 1 1 4 4 4 0 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 OAG06849.1 - 0.11 12.9 0.0 0.7 10.2 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RRN3 PF05327.11 OAG06849.1 - 2.3 6.7 10.4 3.6 6.0 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 OAG06849.1 - 3.4 6.9 17.1 5.5 6.2 17.1 1.3 1 0 0 1 1 1 0 BUD22 Med31 PF05669.12 OAG06850.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 SOH1 DUF3837 PF12939.7 OAG06851.1 - 0.035 14.5 0.1 19 5.7 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) Rdx PF10262.9 OAG06852.1 - 3.7e-31 107.1 0.0 5.3e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family HSP90 PF00183.18 OAG06853.1 - 4.1e-221 735.4 31.6 5e-221 735.1 31.6 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OAG06853.1 - 4.6e-15 56.1 0.1 8.3e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG06853.1 - 5.6e-10 39.2 0.2 5.6e-10 39.2 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 OAG06853.1 - 0.078 13.0 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 Tumour suppressor protein DUF1676 PF07898.13 OAG06853.1 - 1.8 8.6 4.8 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) PIG-S PF10510.9 OAG06854.1 - 1.2e-165 552.3 5.5 1.3e-165 552.1 5.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein MFS_1 PF07690.16 OAG06855.1 - 7.6e-33 113.9 26.0 7.6e-33 113.9 26.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TM140 PF14985.6 OAG06855.1 - 0.019 14.5 1.7 0.019 14.5 1.7 2.3 2 1 0 2 2 2 0 TM140 protein family DUF2407_C PF13373.6 OAG06855.1 - 1.1 9.5 2.9 7.3 6.8 0.9 2.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF3810 PF12725.7 OAG06855.1 - 3.2 7.0 6.8 1.8e+02 1.3 6.8 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Glyco_hydro_88 PF07470.13 OAG06856.1 - 1e-91 307.6 0.5 1.2e-91 307.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 OAG06856.1 - 0.1 11.1 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 ANTH PF07651.16 OAG06857.1 - 6.9e-81 271.3 0.0 6.9e-81 271.3 0.0 2.6 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 OAG06857.1 - 1.1e-56 191.3 10.2 1.1e-56 191.3 10.2 5.8 3 2 2 6 6 6 2 I/LWEQ domain DUF2730 PF10805.8 OAG06857.1 - 0.41 10.8 5.3 5.8 7.1 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) PSII_Pbs27 PF13326.6 OAG06857.1 - 3 8.2 10.7 0.094 13.0 0.9 3.3 2 1 0 2 2 2 0 Photosystem II Pbs27 Slu7 PF11708.8 OAG06858.1 - 7.4e-81 271.8 21.4 7.4e-81 271.8 21.4 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 OAG06858.1 - 0.045 13.5 0.5 0.086 12.6 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle PepSY PF03413.19 OAG06858.1 - 0.34 11.5 3.9 16 6.1 0.0 3.3 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain zf-CCHC PF00098.23 OAG06858.1 - 0.63 10.2 3.1 1.1 9.4 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAG06858.1 - 1 9.2 4.0 2.2 8.1 4.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DNA_pol_B PF00136.21 OAG06859.1 - 1.5e-101 340.4 0.0 2e-101 340.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAG06859.1 - 3.1e-18 66.0 0.1 1.9e-12 47.0 0.0 3.8 2 1 1 3 3 3 3 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAG06859.1 - 1.5e-16 60.6 5.1 3.2e-16 59.5 5.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Sugar_tr PF00083.24 OAG06860.1 - 2.2e-40 138.9 18.6 2.7e-40 138.6 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG06860.1 - 1.1e-22 80.4 23.5 1.5e-22 80.1 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_L37e PF01907.19 OAG06861.1 - 2.7e-27 94.7 12.3 4.2e-27 94.1 12.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 OAG06861.1 - 0.0031 17.5 1.6 0.0049 16.9 1.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 OAG06861.1 - 0.066 12.9 2.2 5.3 6.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 OAG06861.1 - 0.11 12.5 0.6 0.15 12.1 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1258 PF06869.12 OAG06861.1 - 0.86 9.0 3.2 0.71 9.3 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) DUF2688 PF10892.8 OAG06861.1 - 2.4 7.7 6.2 12 5.5 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) CEP63 PF17045.5 OAG06862.1 - 0.001 19.1 14.7 0.019 14.9 14.7 2.3 1 1 0 1 1 1 1 Centrosomal protein of 63 kDa Spc7 PF08317.11 OAG06862.1 - 0.003 16.5 12.2 0.038 12.9 1.8 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Med30 PF11315.8 OAG06862.1 - 0.018 15.3 5.2 0.036 14.3 0.3 2.5 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF4407 PF14362.6 OAG06862.1 - 0.03 13.7 15.0 0.23 10.8 3.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 OAG06862.1 - 0.039 12.8 11.0 0.042 12.7 9.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 OAG06862.1 - 0.1 11.2 5.2 0.14 10.7 5.2 1.2 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 OAG06862.1 - 0.11 12.5 6.7 0.064 13.3 2.5 2.4 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 OAG06862.1 - 0.15 12.4 7.8 0.49 10.7 2.2 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arm-DNA-bind_5 PF17293.2 OAG06862.1 - 0.21 12.0 5.5 1.3 9.5 0.3 2.6 2 0 0 2 2 2 0 Arm DNA-binding domain ABC_tran_CTD PF16326.5 OAG06862.1 - 0.47 10.7 28.6 2.7 8.3 2.5 4.9 3 1 2 5 5 4 0 ABC transporter C-terminal domain Fez1 PF06818.15 OAG06862.1 - 0.56 10.6 16.5 0.29 11.5 12.0 2.3 2 1 0 2 2 2 0 Fez1 DUF948 PF06103.11 OAG06862.1 - 0.56 10.5 2.9 12 6.2 0.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 OAG06862.1 - 0.67 10.0 16.5 10 6.2 4.7 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 OAG06862.1 - 0.68 10.0 16.4 0.95 9.5 4.8 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HrpB7 PF09486.10 OAG06862.1 - 0.78 10.1 11.5 4.6 7.6 2.8 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Kre28 PF17097.5 OAG06862.1 - 0.95 8.4 6.8 2.6 6.9 6.8 1.8 1 1 0 1 1 1 0 Spindle pole body component Atg14 PF10186.9 OAG06862.1 - 1.1 8.3 12.8 0.68 9.0 3.3 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 OAG06862.1 - 1.3 9.4 20.0 4.6 7.6 0.4 4.6 3 1 1 4 4 4 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 OAG06862.1 - 1.5 9.1 14.5 4.1 7.7 7.5 3.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.12 OAG06862.1 - 1.6 9.1 12.5 7.8 6.8 2.8 2.9 2 2 0 2 2 2 0 Plant protein of unknown function (DUF641) RRP36 PF06102.12 OAG06862.1 - 1.7 8.6 11.4 0.74 9.8 4.2 2.4 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 FUSC PF04632.12 OAG06862.1 - 1.7 7.1 8.8 2.7 6.4 8.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc24 PF08286.11 OAG06862.1 - 2.1 8.6 11.0 0.68 10.2 0.6 3.1 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 FAM76 PF16046.5 OAG06862.1 - 4.5 6.5 8.7 3.6 6.8 1.5 2.1 1 1 1 2 2 2 0 FAM76 protein FapA PF03961.13 OAG06862.1 - 5 5.6 8.7 20 3.6 8.7 1.9 1 1 0 1 1 1 0 Flagellar Assembly Protein A Lebercilin PF15619.6 OAG06862.1 - 5.7 6.5 20.0 2.1 8.0 8.9 2.8 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease COG2 PF06148.11 OAG06862.1 - 6.2 6.9 6.6 1.9 8.5 0.2 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 YlqD PF11068.8 OAG06862.1 - 6.4 7.2 13.2 11 6.3 2.9 3.1 2 1 0 2 2 2 0 YlqD protein MCU PF04678.13 OAG06862.1 - 6.6 6.8 8.8 2.9 8.0 4.8 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter GAS PF13851.6 OAG06862.1 - 8.3 5.7 19.0 5.7 6.2 6.3 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 OAG06862.1 - 8.5 6.8 19.3 7.3 7.0 3.1 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 OAG06862.1 - 8.7 6.9 9.2 18 5.9 2.4 2.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 Macoilin PF09726.9 OAG06863.1 - 6.9 5.1 14.8 8.7 4.8 14.8 1.1 1 0 0 1 1 1 0 Macoilin family Cytochrom_B561 PF03188.16 OAG06864.1 - 2.9e-06 27.5 10.1 7.1e-06 26.2 7.0 2.3 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4131 PF13567.6 OAG06864.1 - 0.031 13.9 3.1 3.1 7.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.24 OAG06864.1 - 1.6 8.5 14.7 0.48 10.2 3.7 2.6 1 1 1 2 2 2 0 Fatty acid desaturase Zn_clus PF00172.18 OAG06865.1 - 7.6e-10 38.8 8.0 1.4e-09 37.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG06865.1 - 8.1e-06 25.1 1.3 1.8e-05 23.9 1.1 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Lipase_3 PF01764.25 OAG06869.1 - 5.6e-35 120.3 0.0 8.5e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAG06869.1 - 1.5e-05 24.4 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase3_N PF03893.16 OAG06869.1 - 0.00061 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_8 PF06259.12 OAG06869.1 - 0.0016 18.1 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 OAG06869.1 - 0.0031 18.2 0.1 0.0038 17.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OAG06869.1 - 0.0075 15.9 0.4 0.049 13.2 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.18 OAG06869.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.22 OAG06869.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.20 OAG06869.1 - 0.017 15.2 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.14 OAG06869.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 OAG06869.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Macro PF01661.21 OAG06870.1 - 1.4e-24 86.3 0.0 2.2e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Macro domain FSH1 PF03959.13 OAG06871.1 - 2.2e-62 210.5 0.0 2.7e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAG06871.1 - 1.3e-05 25.9 0.0 3.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG06871.1 - 0.00044 20.0 0.0 0.64 9.6 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG06871.1 - 0.0007 18.9 0.1 0.013 14.7 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 OAG06871.1 - 0.0047 16.4 0.0 1.5 8.2 0.0 2.2 1 1 1 2 2 2 2 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 OAG06871.1 - 0.0053 16.6 0.1 1.5 8.6 0.1 2.4 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAG06871.1 - 0.0075 15.8 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 OAG06871.1 - 0.053 13.6 0.1 1.8 8.6 0.2 2.3 1 1 1 2 2 2 0 Thioesterase domain DUF2974 PF11187.8 OAG06871.1 - 0.058 13.0 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.18 OAG06871.1 - 0.072 12.6 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family PCI PF01399.27 OAG06872.1 - 1.4e-21 76.9 0.1 5.3e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 OAG06872.1 - 3.6e-16 59.0 1.1 8.8e-16 57.7 1.1 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Sugar_tr PF00083.24 OAG06873.1 - 2e-74 251.1 25.9 2.3e-74 250.9 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG06873.1 - 4.1e-14 52.3 37.7 1e-13 51.0 28.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.28 OAG06874.1 - 1.7e-14 54.8 0.0 2.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG06874.1 - 4.2e-10 40.1 0.0 6.7e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1823 PF08853.11 OAG06874.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) RRN9 PF10680.9 OAG06875.1 - 1.5e-13 50.8 6.2 1.2e-12 47.9 6.2 2.6 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Zn_clus PF00172.18 OAG06875.1 - 3e-12 46.4 30.6 3.5e-07 30.2 11.1 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 OAG06877.1 - 1.1e-48 166.4 0.0 1.3e-48 166.2 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aminotran_1_2 PF00155.21 OAG06878.1 - 3.7e-45 154.7 0.0 4.7e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAG06878.1 - 7.3e-10 38.3 0.0 1.6e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG06878.1 - 1.4e-05 23.8 0.0 2.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 OAG06878.1 - 1.8e-05 24.2 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAG06878.1 - 0.0017 17.7 0.0 0.0055 16.1 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 OAG06878.1 - 0.023 13.6 0.3 0.058 12.3 0.3 1.9 1 1 0 1 1 1 0 Allinase ABC2_membrane PF01061.24 OAG06879.1 - 9.5e-39 133.0 23.1 1.7e-38 132.1 23.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAG06879.1 - 1.5e-26 93.5 0.0 2.7e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OAG06879.1 - 9.1e-06 25.0 25.5 9.1e-06 25.0 25.5 2.3 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAG06879.1 - 9.9e-05 22.3 0.4 0.35 10.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG06879.1 - 0.025 14.3 0.1 0.06 13.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG06879.1 - 0.032 14.5 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG06879.1 - 0.035 14.7 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG06879.1 - 0.037 14.4 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAG06879.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 OAG06879.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 OAG06879.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Phage_holin_2_4 PF16082.5 OAG06879.1 - 1.7 8.4 3.7 4.7 7.0 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF3278 PF11683.8 OAG06879.1 - 2.4 8.2 3.8 7.8 6.6 3.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Tyrosinase PF00264.20 OAG06880.1 - 1.8e-51 175.6 0.0 3.1e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase RRM_1 PF00076.22 OAG06882.1 - 3.4e-14 52.4 0.1 2.4e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 OAG06884.1 - 1.9e-40 138.5 0.0 2.8e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG06884.1 - 1.1e-29 103.0 0.0 5.8e-27 94.2 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.23 OAG06884.1 - 0.0048 15.7 0.0 0.0062 15.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain UTP25 PF06862.12 OAG06884.1 - 0.009 14.8 0.0 0.22 10.2 0.0 2.6 3 1 1 4 4 4 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ion_trans_2 PF07885.16 OAG06886.1 - 5.9e-25 87.0 19.0 2.1e-16 59.6 4.6 3.5 4 0 0 4 4 4 2 Ion channel SieB PF14163.6 OAG06886.1 - 0.21 11.1 0.7 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B Lig_chan PF00060.26 OAG06886.1 - 0.64 9.8 8.0 0.089 12.6 1.0 2.8 3 1 0 3 3 3 0 Ligand-gated ion channel DUF2368 PF10166.9 OAG06886.1 - 2 8.0 5.1 19 4.9 0.7 3.0 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2368) RNA_pol_Rpb1_6 PF04992.14 OAG06887.1 - 0.0038 17.1 0.0 0.0055 16.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 DUF2011 PF09428.10 OAG06887.1 - 0.031 14.5 0.2 0.058 13.6 0.2 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) SQS_PSY PF00494.19 OAG06889.1 - 1.9e-38 132.5 0.0 2.5e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF981 PF06168.11 OAG06889.1 - 0.09 12.7 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) SabA_adhesion PF18304.1 OAG06889.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain IF4E PF01652.18 OAG06890.1 - 1.3e-54 184.3 0.9 1.6e-54 184.0 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DnaJ-X PF14308.6 OAG06891.1 - 2.4e-78 262.4 9.2 2.4e-78 262.4 9.2 3.1 2 2 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAG06891.1 - 2.3e-26 91.7 1.0 6.4e-26 90.3 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain PBP PF01161.20 OAG06892.1 - 7.2e-09 36.0 0.1 1.1e-08 35.4 0.1 1.3 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein Methyltransf_11 PF08241.12 OAG06893.1 - 0.026 15.2 0.0 0.057 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG06893.1 - 0.037 14.7 0.0 0.088 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SAP PF02037.27 OAG06895.1 - 5.4e-14 51.6 0.1 1.2e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 OAG06895.1 - 8.1e-06 25.5 3.4 8.1e-06 25.5 3.4 2.5 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG06896.1 - 1.2e-42 145.6 0.3 1.9e-42 145.0 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG06896.1 - 7.5e-21 74.1 0.1 1.3e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 OAG06896.1 - 1.7e-19 69.7 0.2 3.3e-19 68.8 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 OAG06896.1 - 1e-18 68.0 0.0 2.2e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG06896.1 - 1.7e-08 34.8 0.0 2.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 OAG06896.1 - 0.032 14.7 0.0 0.11 13.0 0.0 1.8 1 1 0 1 1 1 0 C6 domain USP8_interact PF08941.10 OAG06896.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 USP8 interacting MARVEL PF01284.23 OAG06897.1 - 8.9e-26 90.7 0.8 1.1e-25 90.4 0.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_C50 PF03568.17 OAG06898.1 - 6e-144 480.0 0.0 1.9e-143 478.4 0.0 1.9 1 0 0 1 1 1 1 Peptidase family C50 TPR_2 PF07719.17 OAG06898.1 - 0.00032 20.6 7.2 2.2 8.6 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG06898.1 - 0.0015 19.0 4.2 1.9 9.0 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG06898.1 - 0.0057 16.9 9.2 0.72 10.2 0.0 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG06898.1 - 0.0072 16.4 0.3 6.4 7.3 0.1 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat CHAT PF12770.7 OAG06898.1 - 0.023 14.1 2.7 0.076 12.4 0.0 3.3 2 1 0 2 2 2 0 CHAT domain DEAD_assoc PF08494.11 OAG06898.1 - 0.097 12.5 2.4 0.65 9.8 0.3 2.5 2 0 0 2 2 2 0 DEAD/H associated TPR_1 PF00515.28 OAG06898.1 - 0.22 11.4 1.5 14 5.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat FliT PF05400.13 OAG06898.1 - 0.23 12.3 9.0 7.4 7.5 0.0 4.9 4 0 0 4 4 4 0 Flagellar protein FliT Metallophos PF00149.28 OAG06900.1 - 3.2e-19 70.3 0.3 5.7e-19 69.4 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG06900.1 - 4.6e-07 30.2 0.0 1.1e-05 25.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.19 OAG06900.1 - 0.045 12.6 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase GCD14_N PF14801.6 OAG06901.1 - 5.8e-09 35.7 0.3 1.5e-08 34.3 0.2 1.7 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term GCD14 PF08704.10 OAG06901.1 - 3.5e-05 23.6 0.0 0.0053 16.5 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 OAG06901.1 - 0.0018 18.1 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OAG06901.1 - 0.045 14.4 0.0 6.1 7.6 0.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain NLPC_P60 PF00877.19 OAG06901.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family SET PF00856.28 OAG06905.1 - 7.5e-09 36.2 0.0 1.6e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 SET domain Coq4 PF05019.13 OAG06906.1 - 3.2e-94 314.4 0.0 3.7e-94 314.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 p450 PF00067.22 OAG06908.1 - 3.5e-74 250.2 0.0 4.7e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 OAG06909.1 - 3.9e-10 39.7 6.0 7.2e-10 38.8 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 OAG06909.1 - 0.0013 18.6 1.2 0.0033 17.4 1.2 1.6 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF2270 PF10028.9 OAG06909.1 - 0.022 14.4 0.0 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2270) DUF1281 PF06924.11 OAG06909.1 - 0.088 12.3 0.1 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) Cyclase PF04199.13 OAG06910.1 - 1.1e-14 54.8 0.0 1.4e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase TRI12 PF06609.13 OAG06911.1 - 2.5e-36 125.3 25.8 3.9e-34 118.1 25.8 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG06911.1 - 1.4e-15 57.1 50.2 8.9e-10 38.0 28.6 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Methyltransf_31 PF13847.6 OAG06912.1 - 1.6e-28 99.4 0.0 2.2e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG06912.1 - 1.9e-20 73.3 0.0 5e-20 72.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG06912.1 - 1.6e-18 67.1 0.0 4.7e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG06912.1 - 8.4e-16 58.5 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG06912.1 - 2.1e-15 57.0 0.0 6.3e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG06912.1 - 2.3e-10 40.2 0.0 2.1e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG06912.1 - 5.3e-09 35.9 0.0 8.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG06912.1 - 5.3e-08 32.5 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 OAG06912.1 - 3e-06 26.4 0.0 4.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 OAG06912.1 - 5.7e-05 23.0 0.0 8.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 OAG06912.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG06912.1 - 0.00024 21.1 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG06912.1 - 0.00064 19.2 0.0 0.00093 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 OAG06912.1 - 0.0012 18.1 0.0 0.0018 17.6 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 OAG06912.1 - 0.0025 17.5 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 OAG06912.1 - 0.0056 16.1 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 OAG06912.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 OAG06912.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.15 OAG06912.1 - 0.058 12.7 0.1 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltr_RsmB-F PF01189.17 OAG06912.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 OAG06912.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.12 OAG06912.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase FAD_binding_7 PF03441.14 OAG06913.1 - 1.7e-55 187.7 0.9 3e-55 186.9 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG06913.1 - 6.6e-42 143.3 0.0 1.1e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Alk_phosphatase PF00245.20 OAG06914.1 - 1.5e-74 251.4 0.5 4.5e-74 249.9 0.5 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 OAG06914.1 - 9.7e-07 28.5 0.1 3.2e-06 26.8 0.1 2.1 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 OAG06914.1 - 6.5e-06 26.0 0.3 1.5e-05 24.7 0.3 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OAG06914.1 - 0.0097 14.6 0.1 0.015 14.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 OAG06914.1 - 0.014 14.8 0.7 0.075 12.4 0.1 2.3 3 0 0 3 3 3 0 Metalloenzyme superfamily HHH_3 PF12836.7 OAG06914.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Vps5 PF09325.10 OAG06915.1 - 2e-87 292.7 3.4 2e-87 292.7 3.4 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 OAG06915.1 - 2.3e-25 88.8 0.2 6.9e-25 87.2 0.0 1.9 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 OAG06915.1 - 0.016 14.9 2.6 0.29 10.8 0.4 2.4 1 1 1 2 2 2 0 BAR domain of APPL family Fib_alpha PF08702.10 OAG06915.1 - 0.21 11.8 0.5 0.47 10.6 0.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5321 PF17254.2 OAG06916.1 - 7.7e-56 187.9 0.2 1e-55 187.6 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) ECH_1 PF00378.20 OAG06917.1 - 1.8e-28 99.5 0.0 3e-28 98.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG06917.1 - 1e-13 51.5 0.0 1.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3292 PF11696.8 OAG06918.1 - 9.2e-08 30.9 4.9 0.0059 15.0 0.1 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3292) PRT_C PF08372.10 OAG06918.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 OAG06918.1 - 0.0083 15.6 0.8 0.029 13.8 0.0 2.0 2 0 0 2 2 2 1 Plant protein of unknown function (DUF639) FAD_binding_4 PF01565.23 OAG06919.1 - 8.5e-21 74.1 1.1 1.5e-20 73.4 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain UL11 PF11094.8 OAG06919.1 - 0.0024 17.7 0.1 0.009 15.9 0.0 2.0 2 0 0 2 2 2 1 Membrane-associated tegument protein Tannase PF07519.11 OAG06921.1 - 4.4e-23 81.9 2.0 3.7e-17 62.4 0.0 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase HPIP PF15226.6 OAG06921.1 - 0.19 12.1 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family NUDIX PF00293.28 OAG06922.1 - 8.5e-13 48.5 0.1 2.3e-12 47.1 0.0 1.7 1 1 2 3 3 3 1 NUDIX domain Peroxidase_2 PF01328.17 OAG06924.1 - 4.7e-50 170.7 0.1 6e-50 170.4 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Exonuc_VII_L PF02601.15 OAG06925.1 - 0.0025 17.4 3.0 0.0025 17.4 3.0 3.1 2 1 1 3 3 3 1 Exonuclease VII, large subunit Sec2p PF06428.11 OAG06925.1 - 0.0047 16.9 3.4 0.0047 16.9 3.4 4.0 3 2 1 4 4 4 1 GDP/GTP exchange factor Sec2p FapA PF03961.13 OAG06925.1 - 0.0069 15.0 2.9 0.014 14.0 2.9 1.6 1 0 0 1 1 1 1 Flagellar Assembly Protein A Prefoldin PF02996.17 OAG06925.1 - 0.2 11.6 0.1 0.2 11.6 0.1 4.1 5 1 0 5 5 5 0 Prefoldin subunit AAA_13 PF13166.6 OAG06925.1 - 0.22 10.1 12.7 0.12 11.0 8.0 2.0 2 0 0 2 2 2 0 AAA domain Retrotran_gag_2 PF14223.6 OAG06925.1 - 0.23 11.1 3.2 0.11 12.2 0.3 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Cep57_CLD_2 PF14197.6 OAG06925.1 - 0.34 11.0 17.4 0.62 10.2 6.6 4.8 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 Bacillus_HBL PF05791.11 OAG06925.1 - 1.3 8.8 4.9 8 6.2 0.1 3.0 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF1351 PF07083.11 OAG06925.1 - 1.7 8.4 14.4 0.017 14.9 3.3 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1351) Fib_alpha PF08702.10 OAG06925.1 - 1.9 8.6 14.4 0.021 15.0 3.5 3.1 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Rootletin PF15035.6 OAG06925.1 - 5.9 6.9 21.0 0.074 13.1 11.7 2.6 2 2 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Fzo_mitofusin PF04799.13 OAG06925.1 - 8.1 6.0 12.9 5.5 6.5 0.6 4.0 3 1 1 4 4 4 0 fzo-like conserved region L51_S25_CI-B8 PF05047.16 OAG06926.1 - 8.3e-17 60.9 0.0 1.1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.13 OAG06927.1 - 8.2e-44 148.2 0.1 1.1e-43 147.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 OAG06927.1 - 0.087 12.9 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Keratin_2_head PF16208.5 OAG06928.1 - 0.45 10.7 11.3 0.69 10.0 11.3 1.2 1 0 0 1 1 1 0 Keratin type II head An_peroxidase PF03098.15 OAG06931.1 - 1.5e-38 132.7 0.0 6.7e-28 97.6 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAG06931.1 - 5.5e-10 38.6 0.0 4.4e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Steroid_dh PF02544.16 OAG06932.1 - 4.8e-35 120.7 0.9 6.3e-35 120.4 0.9 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAG06932.1 - 0.00012 21.7 1.0 0.00017 21.2 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OAG06932.1 - 0.01 16.2 2.7 0.028 14.8 1.2 2.3 2 1 0 2 2 2 0 Phospholipid methyltransferase DUF4044 PF13253.6 OAG06932.1 - 0.072 12.6 0.2 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) ATE_C PF04377.15 OAG06933.1 - 2.2e-48 164.3 4.7 3.4e-48 163.7 4.7 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 OAG06933.1 - 1.4e-22 79.9 0.0 3.9e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 OAG06933.1 - 0.068 13.3 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.28 OAG06934.1 - 1e-16 61.2 0.5 1.3e-16 60.8 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain adh_short PF00106.25 OAG06936.1 - 1.4e-41 142.1 0.2 2e-41 141.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG06936.1 - 9.3e-29 100.6 0.1 2.9e-28 99.0 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG06936.1 - 3.9e-08 33.4 0.4 3.9e-07 30.1 0.4 2.0 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 OAG06936.1 - 0.00027 20.9 0.1 0.00059 19.8 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 OAG06936.1 - 0.0011 19.1 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 OAG06936.1 - 0.0037 16.4 0.1 0.0059 15.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glu_dehyd_C PF16912.5 OAG06936.1 - 0.011 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 OAG06936.1 - 0.049 13.5 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Arc PF03869.14 OAG06936.1 - 0.12 12.3 0.0 0.38 10.6 0.0 1.9 1 0 0 1 1 1 0 Arc-like DNA binding domain Chitin_bind_1 PF00187.19 OAG06937.1 - 6.5e-15 55.3 67.2 6.8e-08 32.9 16.4 4.0 3 2 0 3 3 3 3 Chitin recognition protein PAPA-1 PF04795.12 OAG06938.1 - 2.6e-26 92.2 9.3 2.6e-26 92.2 9.3 3.6 3 2 0 3 3 3 1 PAPA-1-like conserved region Pannexin_like PF12534.8 OAG06938.1 - 3.1 6.8 5.5 7.4 5.6 5.5 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF726 PF05277.12 OAG06939.1 - 6.1e-127 423.3 0.8 9e-127 422.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Pex14_N PF04695.13 OAG06939.1 - 1.8e-21 77.5 4.6 1.8e-21 77.5 4.6 5.4 5 2 0 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Thioesterase PF00975.20 OAG06939.1 - 0.014 15.6 0.1 0.062 13.4 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain SNARE PF05739.19 OAG06939.1 - 0.081 12.9 0.1 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 SNARE domain Abhydrolase_6 PF12697.7 OAG06939.1 - 0.22 12.1 1.2 0.57 10.7 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase family EIIBC-GUT_N PF03612.14 OAG06939.1 - 7.7 6.2 10.9 13 5.5 0.7 3.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus SOG2 PF10428.9 OAG06941.1 - 0.074 12.2 12.9 0.079 12.2 12.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 OAG06941.1 - 5.2 5.6 10.4 5.3 5.6 10.4 1.0 1 0 0 1 1 1 0 Hamartin protein Glu-tRNAGln PF02686.15 OAG06942.1 - 4.7e-11 42.8 0.4 2.3e-10 40.6 0.4 2.0 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 OAG06943.1 - 2.8e-111 371.5 14.7 3.1e-111 371.3 14.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 OAG06943.1 - 0.00029 20.7 20.2 1.5 9.1 0.3 6.3 5 2 2 7 7 7 3 Tetratricopeptide repeat Hep_59 PF07052.11 OAG06943.1 - 0.037 14.8 0.3 0.071 13.9 0.3 1.5 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 TPR_8 PF13181.6 OAG06943.1 - 0.11 12.8 10.1 1.6 9.1 0.2 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG06943.1 - 1.1 10.1 14.5 25 5.8 0.0 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG06943.1 - 4.1 7.4 17.0 6.2 6.8 0.4 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.22 OAG06945.1 - 1.3e-56 190.5 1.4 1.5e-56 190.3 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF4410 PF14366.6 OAG06945.1 - 0.052 13.5 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) SMAP PF15477.6 OAG06945.1 - 2.1 9.4 7.9 0.59 11.1 4.3 2.0 2 1 0 2 2 2 0 Small acidic protein family OSCP PF00213.18 OAG06947.1 - 3.1e-45 154.4 1.8 3.9e-45 154.0 1.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Peptidase_M54 PF07998.11 OAG06947.1 - 0.08 12.9 0.0 5.3 7.0 0.0 2.1 1 1 1 2 2 2 0 Peptidase family M54 CLN3 PF02487.17 OAG06948.1 - 8.3e-163 542.1 4.8 9.5e-163 541.9 4.8 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 OAG06948.1 - 0.00016 20.7 5.7 0.00016 20.7 5.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Rxt3 PF08642.10 OAG06949.1 - 4.9e-34 117.8 0.2 1.4e-33 116.4 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OAG06949.1 - 5.4e-05 23.2 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 2 LCCL domain 6PF2K PF01591.18 OAG06950.1 - 1.8e-83 279.2 0.1 2.6e-83 278.7 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG06950.1 - 2.1e-36 125.5 0.0 3.7e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAG06950.1 - 1.3e-05 25.4 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAG06950.1 - 0.00075 19.0 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Glyco_hydro_3_C PF01915.22 OAG06951.1 - 7.1e-50 169.8 0.0 1.7e-49 168.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG06951.1 - 1.6e-42 146.0 0.0 2.4e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG06951.1 - 6.9e-17 61.3 4.5 8.5e-10 38.6 0.7 2.5 2 0 0 2 2 2 2 Fibronectin type III-like domain DUF3176 PF11374.8 OAG06952.1 - 6.1e-36 122.9 0.4 6.1e-36 122.9 0.4 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) Trp_oprn_chp PF09534.10 OAG06952.1 - 0.54 10.0 6.9 2.5 7.9 0.3 2.8 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3040 PF11239.8 OAG06952.1 - 0.74 10.1 3.3 31 4.9 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) p450 PF00067.22 OAG06954.1 - 3.6e-12 45.8 0.0 4.1e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Citrate_synt PF00285.21 OAG06955.1 - 3.3e-98 329.1 0.0 4.1e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 OAG06956.1 - 1.8e-190 633.9 0.0 2.1e-190 633.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAG06956.1 - 3.2e-09 36.6 0.0 2.5e-08 33.7 0.0 2.1 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase DLH PF01738.18 OAG06957.1 - 0.02 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.16 OAG06959.1 - 9.4e-43 146.5 48.7 9.4e-43 146.5 48.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF799 PF05643.11 OAG06959.1 - 0.062 12.9 0.1 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative bacterial lipoprotein (DUF799) Fungal_trans_2 PF11951.8 OAG06960.1 - 4.4e-07 29.1 3.4 3e-06 26.3 1.5 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Peptidase_A22B PF04258.13 OAG06961.1 - 3.4e-66 223.7 5.6 5.6e-65 219.7 5.6 2.5 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OAG06961.1 - 0.0019 17.7 4.8 0.0019 17.7 4.8 2.1 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease DNA_pack_C PF02499.15 OAG06965.1 - 0.026 13.5 0.3 0.047 12.6 0.1 1.4 1 1 0 1 1 1 0 Probable DNA packing protein, C-terminus RCC1_2 PF13540.6 OAG06966.1 - 2.6e-06 27.1 5.2 0.038 13.8 0.3 4.2 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OAG06966.1 - 3.1e-05 24.5 6.1 0.31 11.7 0.0 5.1 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat PRIMA1 PF16101.5 OAG06967.1 - 0.018 15.1 0.2 0.024 14.7 0.2 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMEM132D_C PF15706.5 OAG06967.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TIM21 PF08294.11 OAG06967.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 TIM21 Sugar_tr PF00083.24 OAG06967.1 - 0.19 10.5 0.0 0.24 10.2 0.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter PHD PF00628.29 OAG06968.1 - 1.5e-05 24.8 4.4 2.6e-05 24.0 4.4 1.4 1 0 0 1 1 1 1 PHD-finger CBP4 PF07960.11 OAG06970.1 - 1.2e-28 99.5 0.6 1.5e-28 99.3 0.6 1.1 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 OAG06970.1 - 0.0012 18.7 0.6 0.0044 16.9 0.0 1.9 1 1 1 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF2852 PF11014.8 OAG06970.1 - 1.5 9.0 7.6 0.19 11.9 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Sel1 PF08238.12 OAG06971.1 - 5e-39 131.9 27.5 3.8e-08 33.8 0.2 8.1 8 0 0 8 8 8 7 Sel1 repeat ANAPC3 PF12895.7 OAG06971.1 - 0.023 14.9 0.6 0.023 14.9 0.6 2.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAG06971.1 - 2.1 9.2 13.3 4.2 8.2 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Ifi-6-16 PF06140.13 OAG06973.1 - 1.2e-08 34.8 34.8 2.4e-08 33.8 34.8 1.6 1 1 0 1 1 1 1 Interferon-induced 6-16 family adh_short PF00106.25 OAG06974.1 - 2.5e-13 49.9 0.0 2.2e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG06974.1 - 6.9e-12 45.4 0.0 9.9e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG06974.1 - 2.6e-05 24.2 0.0 7.6e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Fungal_trans_2 PF11951.8 OAG06975.1 - 1.9e-54 185.0 0.3 2.6e-54 184.5 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG06975.1 - 4e-06 26.8 11.7 6.7e-06 26.1 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.20 OAG06977.1 - 2.7e-26 92.8 0.0 6.4e-26 91.6 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family Glyco_hydro_43 PF04616.14 OAG06978.1 - 2.6e-24 86.0 0.0 1.2e-23 83.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_35 PF01301.19 OAG06980.1 - 1.4e-89 300.9 0.7 2.8e-89 299.8 0.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAG06980.1 - 8.7e-60 200.3 9.6 1.5e-34 119.0 0.1 3.4 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 OAG06980.1 - 8.4e-59 198.4 3.9 1.5e-58 197.6 3.9 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 OAG06980.1 - 1.1e-24 85.8 0.5 3.4e-24 84.2 0.1 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Roc PF08477.13 OAG06980.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG06980.1 - 0.12 12.0 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 Ras family Arylsulfotran_2 PF14269.6 OAG06981.1 - 7.8e-61 206.0 1.8 1.3e-60 205.4 1.8 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG06981.1 - 0.00018 20.5 0.9 0.0028 16.6 0.5 2.3 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) DUF3328 PF11807.8 OAG06982.1 - 0.012 15.4 8.4 2.4 7.9 8.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) MFS_1 PF07690.16 OAG06983.1 - 1.2e-45 155.9 42.2 1.2e-45 155.9 42.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG06983.1 - 4.4e-13 48.9 27.9 1.3e-11 44.0 16.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAG06983.1 - 1.4e-07 30.3 17.7 2.1e-07 29.8 17.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Helo_like_N PF17111.5 OAG06984.1 - 0.00015 21.2 1.1 0.00073 19.0 0.0 2.7 2 1 0 3 3 3 1 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 OAG06984.1 - 0.049 14.1 0.1 12 6.5 0.0 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IMS PF00817.20 OAG06986.1 - 3.3e-39 134.3 0.0 4.9e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAG06986.1 - 1e-17 64.9 0.1 4.8e-17 62.7 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 OAG06986.1 - 0.006 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 OAG06986.1 - 0.067 13.5 0.1 0.67 10.4 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif Pyridoxal_deC PF00282.19 OAG06987.1 - 1.1e-15 57.3 0.0 1.6e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAG06987.1 - 4.8e-07 29.1 0.0 8.7e-07 28.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG06987.1 - 0.00086 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OAG06987.1 - 0.027 13.0 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1775 PF07987.11 OAG06987.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) Dicty_REP PF05086.12 OAG06989.1 - 1.9 6.3 5.7 2.3 6.1 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tannase PF07519.11 OAG06990.1 - 8.8e-102 341.4 2.1 1e-101 341.2 2.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF4837 PF16125.5 OAG06990.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) Wbp11 PF09429.10 OAG06992.1 - 1.8e-21 76.3 15.1 1.8e-21 76.3 15.1 2.3 3 0 0 3 3 3 1 WW domain binding protein 11 HSP9_HSP12 PF04119.12 OAG06993.1 - 1.6e-25 89.3 1.2 1.6e-25 89.3 1.2 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.6 OAG06993.1 - 0.64 10.4 6.6 2.4 8.5 4.9 2.7 2 1 0 2 2 2 0 MT0933-like antitoxin protein CtnDOT_TraJ PF07863.11 OAG06993.1 - 1 10.1 5.9 0.9 10.2 4.0 1.7 1 1 1 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Glyco_hydro_76 PF03663.14 OAG06994.1 - 5.1e-31 108.5 10.9 6.2e-31 108.2 10.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG06994.1 - 7.7e-05 21.9 1.1 0.13 11.3 1.3 2.8 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 OAG06994.1 - 0.029 12.9 0.1 0.037 12.5 0.1 1.2 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 DUF1996 PF09362.10 OAG06995.1 - 3.8e-84 282.3 1.2 5.4e-84 281.8 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HhH-GPD PF00730.25 OAG06996.1 - 2.5e-06 27.9 0.0 4.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG06996.1 - 0.049 13.5 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 OAG06996.1 - 0.1 13.2 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Abhydrolase_2 PF02230.16 OAG06997.1 - 6.1e-59 199.5 0.0 7.3e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAG06997.1 - 4.4e-06 27.5 0.1 9e-06 26.4 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG06997.1 - 1.4e-05 24.7 0.5 0.00058 19.4 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG06997.1 - 2.9e-05 23.5 0.7 0.019 14.2 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 OAG06997.1 - 3.9e-05 23.3 0.0 5.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 OAG06997.1 - 0.00017 21.3 0.0 0.0008 19.1 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 OAG06997.1 - 0.0078 16.1 0.1 0.46 10.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAG06997.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Esterase_phd PF10503.9 OAG06997.1 - 0.051 13.1 0.0 0.76 9.2 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydro_lipase PF04083.16 OAG06997.1 - 0.077 12.6 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF2974 PF11187.8 OAG06997.1 - 0.1 12.2 0.1 0.23 11.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 OAG06997.1 - 0.11 12.1 0.4 0.23 11.1 0.4 1.9 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.12 OAG06997.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 OAG06997.1 - 0.14 11.3 0.0 6.3 5.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Ifi-6-16 PF06140.13 OAG06998.1 - 3e-05 23.8 1.1 5.4e-05 23.0 1.1 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family MFS_1 PF07690.16 OAG06999.1 - 2.3e-34 118.9 33.8 2.3e-34 118.9 33.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily KH_1 PF00013.29 OAG07000.1 - 5.1e-46 154.3 14.3 3e-15 55.8 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAG07000.1 - 8.2e-13 48.0 5.4 0.00058 19.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAG07000.1 - 2.1e-09 37.1 1.7 0.047 13.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAG07000.1 - 0.0019 18.3 4.4 8.5 6.5 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 OAG07000.1 - 0.014 15.4 0.0 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 KH-like RNA-binding domain RabGAP-TBC PF00566.18 OAG07001.1 - 1.1e-49 169.0 1.8 1.1e-49 169.0 1.8 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PspB PF06667.12 OAG07001.1 - 0.0064 16.5 6.4 0.008 16.2 1.6 2.7 2 0 0 2 2 2 1 Phage shock protein B Fez1 PF06818.15 OAG07001.1 - 3.8 7.9 28.2 2.8 8.4 23.4 2.3 2 0 0 2 2 2 0 Fez1 p450 PF00067.22 OAG07002.1 - 5.7e-52 177.0 0.0 5e-51 173.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 SPO22 PF08631.10 OAG07004.1 - 1.9e-66 224.4 10.8 1.9e-66 224.4 10.8 4.1 5 0 0 5 5 5 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 OAG07004.1 - 0.00057 20.1 1.3 0.00057 20.1 1.3 4.2 6 0 0 6 6 6 1 Tetratricopeptide repeat MazG-like PF12643.7 OAG07004.1 - 0.008 16.4 0.0 0.16 12.2 0.0 2.9 2 0 0 2 2 2 1 MazG-like family TPR_2 PF07719.17 OAG07004.1 - 0.15 12.2 12.8 0.18 12.0 0.4 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG07004.1 - 0.74 10.8 12.0 41 5.4 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG07004.1 - 1.1 9.9 4.0 44 4.8 0.0 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG07004.1 - 2.1 9.2 6.0 4.7 8.1 0.0 4.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Zn_clus PF00172.18 OAG07005.1 - 7.4e-06 26.0 8.1 1.4e-05 25.1 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4614 PF15391.6 OAG07005.1 - 3.7 7.5 8.4 4.3 7.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) CENP-Q PF13094.6 OAG07006.1 - 1.8e-30 106.3 3.8 1.8e-30 106.3 3.8 3.0 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit EzrA PF06160.12 OAG07006.1 - 0.00026 19.3 5.8 0.00026 19.3 5.8 1.5 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Imm49 PF15575.6 OAG07006.1 - 0.015 15.1 2.5 0.015 15.1 2.5 2.4 1 1 1 2 2 2 0 Immunity protein 49 Utp13 PF08625.11 OAG07006.1 - 0.39 10.6 4.0 0.29 11.0 1.1 2.1 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Cas_Csy4 PF09618.10 OAG07006.1 - 9.6 6.3 9.7 0.34 11.0 2.7 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) HSP70 PF00012.20 OAG07007.1 - 1e-11 43.8 0.0 3.1e-10 38.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 OAG07007.1 - 0.02 15.3 0.0 0.46 10.9 0.0 2.4 2 0 0 2 2 2 0 Cell division protein FtsA DUF4795 PF16043.5 OAG07008.1 - 0.0079 15.8 3.7 0.23 11.0 2.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) HAP1_N PF04849.13 OAG07008.1 - 0.15 11.2 14.9 0.42 9.8 14.9 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.8 OAG07008.1 - 0.2 11.6 9.1 0.32 11.0 2.7 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Taxilin PF09728.9 OAG07008.1 - 0.22 10.7 12.0 1.3 8.2 1.2 2.4 2 0 0 2 2 2 0 Myosin-like coiled-coil protein GrpE PF01025.19 OAG07008.1 - 0.23 11.1 5.2 6.5 6.4 0.2 2.6 2 0 0 2 2 2 0 GrpE YabA PF06156.13 OAG07008.1 - 0.29 11.8 8.7 0.93 10.2 0.1 3.2 2 1 1 3 3 3 0 Initiation control protein YabA TraI PF07057.11 OAG07008.1 - 1.1 9.4 5.5 9.1 6.4 0.0 3.4 4 0 0 4 4 4 0 DNA helicase TraI Cnn_1N PF07989.11 OAG07008.1 - 1.4 9.1 11.0 2.1 8.6 2.0 3.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 EzrA PF06160.12 OAG07008.1 - 2.1 6.4 12.0 0.14 10.3 2.6 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA TPD52 PF04201.15 OAG07008.1 - 6 6.5 9.4 0.66 9.6 0.3 2.6 2 1 0 2 2 2 0 Tumour protein D52 family FlaC_arch PF05377.11 OAG07008.1 - 6.8 7.2 6.6 3 8.3 0.5 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 OAG07008.1 - 9.1 6.5 11.5 3.1 8.0 1.8 3.4 2 1 1 3 3 3 0 bZIP transcription factor RasGAP_C PF03836.15 OAG07008.1 - 9.5 6.4 8.9 30 4.8 5.7 2.8 2 1 0 2 2 2 0 RasGAP C-terminus RINGv PF12906.7 OAG07009.1 - 7.9e-10 38.7 4.2 2.7e-09 37.0 1.6 2.2 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 OAG07009.1 - 0.023 14.8 1.6 0.5 10.5 0.8 2.3 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 OAG07009.1 - 0.03 14.7 5.2 0.71 10.3 1.8 2.2 2 0 0 2 2 2 0 Ring finger domain UNC-93 PF05978.16 OAG07009.1 - 0.052 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 PHD PF00628.29 OAG07009.1 - 0.86 9.6 6.5 0.24 11.3 2.8 1.9 2 0 0 2 2 2 0 PHD-finger zf-BED PF02892.15 OAG07009.1 - 1.8 8.6 4.2 0.62 10.1 0.8 1.9 2 0 0 2 2 2 0 BED zinc finger zf-RING_4 PF14570.6 OAG07009.1 - 9.9 6.0 9.0 2.6 7.9 5.2 2.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain AKAP7_NLS PF10469.9 OAG07012.1 - 1.4e-22 80.6 0.0 7.6e-22 78.2 0.0 2.0 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 OAG07012.1 - 0.13 12.5 0.1 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 LigT like Phosphoesterase Hpt PF01627.23 OAG07013.1 - 5e-12 45.9 0.0 7.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Hpt domain Aminotran_1_2 PF00155.21 OAG07014.1 - 9e-89 298.2 0.0 1e-88 298.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ILEI PF15711.5 OAG07014.1 - 0.065 13.7 0.0 0.43 11.1 0.0 2.2 2 0 0 2 2 2 0 Interleukin-like EMT inducer MMR_HSR1 PF01926.23 OAG07015.1 - 0.00096 19.2 0.0 2.4 8.2 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase Glyco_transf_34 PF05637.12 OAG07016.1 - 1.9e-66 224.2 0.0 2.4e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family BNR_assoc_N PF14873.6 OAG07016.1 - 0.0094 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain of BNR-repeat neuraminidase PMI_typeI PF01238.21 OAG07017.1 - 1e-75 255.3 0.0 1.7e-74 251.3 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 OAG07017.1 - 1.7e-06 27.6 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG07017.1 - 0.0064 16.4 0.0 0.57 10.1 0.0 2.8 2 0 0 2 2 2 1 AraC-like ligand binding domain Hs1pro-1_C PF07014.12 OAG07018.1 - 0.027 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus TPR_16 PF13432.6 OAG07018.1 - 1.8 9.3 6.5 9.6 7.0 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 OAG07021.1 - 0.0016 18.5 1.4 0.2 11.7 0.1 2.9 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 OAG07021.1 - 0.007 16.6 3.7 5.9 7.2 0.2 4.3 3 2 0 4 4 4 2 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 OAG07021.1 - 0.038 14.1 0.1 34 4.5 0.0 3.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1411 PF07199.11 OAG07021.1 - 0.1 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) CCM2_C PF16545.5 OAG07021.1 - 0.19 12.2 0.0 0.52 10.9 0.0 1.7 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology ApoLp-III PF07464.11 OAG07021.1 - 0.62 10.2 2.4 9 6.4 0.5 3.3 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF4381 PF14316.6 OAG07021.1 - 3.6 7.8 5.2 43 4.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Vps39_1 PF10366.9 OAG07023.1 - 6.1e-32 110.1 0.0 1.6e-30 105.5 0.0 3.3 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 OAG07023.1 - 7.4e-30 103.6 0.0 2.5e-29 101.9 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OAG07023.1 - 4.5e-22 79.0 0.0 4.6e-21 75.7 0.0 2.1 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 OAG07023.1 - 2.9e-08 33.7 5.3 3.3e-08 33.5 1.8 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_16 PF13432.6 OAG07023.1 - 0.0018 18.9 0.2 0.12 13.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG07023.1 - 0.005 16.6 6.5 4.6 7.2 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG07023.1 - 0.044 13.9 4.9 20 5.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC8 PF04049.13 OAG07023.1 - 0.056 13.5 0.5 2.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_19 PF14559.6 OAG07023.1 - 0.095 13.2 4.3 1.9 9.1 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 OAG07023.1 - 0.17 12.2 0.2 8.8 6.8 0.0 3.4 3 0 0 3 3 3 0 PPR repeat TPR_12 PF13424.6 OAG07023.1 - 0.27 11.5 9.8 4 7.8 0.1 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG07023.1 - 0.47 10.7 1.7 8.6 6.7 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OAG07023.1 - 3.1 8.2 7.4 5.8 7.4 0.8 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Gon7 PF08738.10 OAG07024.1 - 2.2e-09 37.4 1.5 3.3e-09 36.8 0.3 1.8 1 1 1 2 2 2 1 Gon7 family BTB PF00651.31 OAG07025.1 - 5.7e-09 36.2 0.1 1.2e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.7 OAG07025.1 - 0.0076 16.2 7.0 0.096 12.7 2.7 3.3 2 1 0 2 2 2 1 Transposase zinc-ribbon domain DUF2752 PF10825.8 OAG07025.1 - 3.2 7.9 5.5 2.9 8.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) Cutinase PF01083.22 OAG07026.1 - 5.1e-43 147.1 1.8 6.6e-43 146.7 1.8 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 OAG07026.1 - 0.0049 16.5 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 OAG07026.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PE-PPE PF08237.11 OAG07026.1 - 0.01 15.4 0.2 0.019 14.5 0.2 1.4 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 OAG07026.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) LysM PF01476.20 OAG07027.1 - 0.024 14.7 0.1 0.071 13.2 0.0 1.8 2 0 0 2 2 2 0 LysM domain ING PF12998.7 OAG07028.1 - 0.049 14.2 0.2 0.17 12.5 0.1 2.0 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1996 PF09362.10 OAG07029.1 - 2.5e-78 263.3 0.7 3.1e-78 263.0 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TruB_N PF01509.18 OAG07030.1 - 3.5e-40 137.8 0.0 1.5e-38 132.5 0.0 2.3 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAG07030.1 - 1.4e-06 28.4 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Sugar_tr PF00083.24 OAG07031.1 - 1.6e-44 152.5 21.5 2.3e-33 115.8 12.8 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG07031.1 - 0.00026 20.0 22.9 0.00026 20.0 22.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily GCN5L1 PF06320.13 OAG07033.1 - 5.3e-21 74.9 4.3 6.3e-21 74.7 4.3 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Sec34 PF04136.15 OAG07033.1 - 0.0083 16.0 0.1 0.0097 15.8 0.1 1.1 1 0 0 1 1 1 1 Sec34-like family OmpH PF03938.14 OAG07033.1 - 0.062 13.6 2.3 0.075 13.4 2.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_GPO PF05929.11 OAG07033.1 - 0.067 12.8 2.9 0.075 12.7 2.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Syntaxin-6_N PF09177.11 OAG07033.1 - 0.071 13.7 3.6 0.092 13.3 0.9 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF913 PF06025.12 OAG07034.1 - 3.3e-118 394.9 0.0 3.3e-118 394.9 0.0 7.6 8 1 0 8 8 8 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 OAG07034.1 - 1.1e-98 331.0 0.0 1.1e-98 331.0 0.0 4.6 6 0 0 6 6 6 1 Domain of Unknown Function (DUF908) HECT PF00632.25 OAG07034.1 - 3.8e-92 309.1 0.0 7.3e-92 308.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 OAG07034.1 - 1.6e-26 90.9 19.4 1.3e-10 40.3 4.2 4.0 3 0 0 3 3 3 3 Ubiquitin binding region adh_short PF00106.25 OAG07035.1 - 9.7e-33 113.3 0.2 2.4e-32 112.0 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07035.1 - 3.7e-19 69.2 0.2 5.4e-19 68.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07035.1 - 2e-08 34.4 0.0 2.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Pea-VEAacid PF08111.11 OAG07035.1 - 2.7 8.5 4.6 0.6 10.5 0.4 2.1 2 0 0 2 2 2 0 Pea-VEAacid family MFS_1 PF07690.16 OAG07036.1 - 2.2e-20 72.9 63.2 1.1e-19 70.7 62.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG07036.1 - 9.4e-15 54.0 21.9 1.4e-14 53.5 21.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GFO_IDH_MocA PF01408.22 OAG07037.1 - 6e-17 62.6 0.1 9.7e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG07037.1 - 4.9e-05 24.0 0.1 8.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 OAG07038.1 - 4.1e-23 82.5 0.0 7.8e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG07038.1 - 0.0021 18.7 0.0 0.0034 18.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain VitD-bind_III PF09164.10 OAG07038.1 - 0.18 11.8 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Vitamin D binding protein, domain III SNF2_N PF00176.23 OAG07039.1 - 9.5e-22 77.2 1.5 1.5e-20 73.2 1.5 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 OAG07039.1 - 2.3e-20 73.3 0.0 6e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase ResIII PF04851.15 OAG07039.1 - 0.077 13.0 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Asp PF00026.23 OAG07040.1 - 1.6e-15 57.4 0.2 2.1e-15 57.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TrkA_C PF02080.21 OAG07041.1 - 0.0028 17.4 0.3 0.16 11.8 0.0 2.7 2 0 0 2 2 2 1 TrkA-C domain DUF3117 PF11314.8 OAG07041.1 - 0.034 13.9 1.3 0.053 13.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) DUF2183 PF09949.9 OAG07043.1 - 3.2e-32 110.8 0.0 8.8e-32 109.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) adh_short PF00106.25 OAG07043.1 - 5e-21 75.0 0.0 1.9e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07043.1 - 4.4e-11 42.8 0.0 2.4e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07043.1 - 8.5e-06 25.8 0.2 2.5e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 KR domain LNS2 PF08235.13 OAG07043.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) 2-Hacid_dh_C PF02826.19 OAG07043.1 - 0.13 11.6 0.1 3.5 7.0 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dicty_REP PF05086.12 OAG07043.1 - 0.26 9.2 1.5 0.42 8.5 1.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LSM PF01423.22 OAG07044.1 - 3.9e-15 55.3 0.0 6.7e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain Nfu_N PF08712.11 OAG07048.1 - 2.5e-28 97.9 0.0 1.4e-27 95.6 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OAG07048.1 - 1.8e-27 95.3 0.1 3e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 OAG07048.1 - 0.013 15.6 0.4 0.024 14.7 0.4 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus NAD_binding_4 PF07993.12 OAG07049.1 - 6.4e-70 235.2 0.0 1.8e-69 233.8 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 OAG07049.1 - 6.1e-66 222.8 0.0 8.9e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAG07049.1 - 4.6e-09 36.5 0.1 1.2e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAG07049.1 - 1.4e-07 31.2 0.0 3.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 OAG07049.1 - 1.4e-06 29.2 0.0 1.1e-05 26.3 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 OAG07049.1 - 3.2e-06 27.2 0.1 2.5e-05 24.2 0.1 2.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG07049.1 - 0.00024 20.2 0.0 0.00074 18.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG07049.1 - 0.0067 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RAP PF08373.10 OAG07049.1 - 0.21 11.7 0.0 0.5 10.5 0.0 1.6 1 0 0 1 1 1 0 RAP domain Nuc_deoxyri_tr2 PF15891.5 OAG07051.1 - 4.6e-25 88.0 0.0 5.7e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like DUF1491 PF07372.12 OAG07052.1 - 0.15 12.4 0.1 0.28 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1491) Ribosomal_L30 PF00327.20 OAG07053.1 - 4.4e-13 48.9 0.3 5.7e-13 48.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PGBA_C PF15437.6 OAG07053.1 - 0.013 15.9 0.3 0.016 15.6 0.3 1.1 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal HET PF06985.11 OAG07054.1 - 1.7e-32 112.8 0.1 2.6e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dynactin PF12455.8 OAG07055.1 - 1.9e-41 142.2 1.5 1.9e-41 142.2 1.5 3.7 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 OAG07055.1 - 2.6e-20 72.2 0.1 4.6e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 OAG07055.1 - 0.0004 19.8 0.1 0.0004 19.8 0.1 5.1 2 2 2 5 5 4 1 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 OAG07055.1 - 0.013 15.6 79.1 0.018 15.0 19.3 5.3 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoO PF09769.9 OAG07055.1 - 0.19 11.7 13.2 0.067 13.2 1.0 4.9 3 1 2 5 5 5 0 Apolipoprotein O Fungal_trans_2 PF11951.8 OAG07055.1 - 0.2 10.4 1.3 0.79 8.5 1.3 2.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3877 PF12993.7 OAG07055.1 - 0.69 9.7 14.5 5.1 6.9 0.4 3.7 1 1 2 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3877) RHH_8 PF17723.1 OAG07055.1 - 0.97 9.6 6.1 5 7.3 0.3 3.0 2 0 0 2 2 2 0 Ribbon-Helix-Helix transcriptional regulator family MscS_porin PF12795.7 OAG07055.1 - 3.1 7.3 91.6 0.26 10.8 18.1 5.6 4 2 1 5 5 5 0 Mechanosensitive ion channel porin domain RTBV_P46 PF06216.11 OAG07055.1 - 3.8 6.3 12.7 0.32 9.8 1.0 3.6 3 1 1 4 4 4 0 Rice tungro bacilliform virus P46 protein FAA_hydro_N_2 PF18288.1 OAG07055.1 - 9.3 6.7 8.3 5.5 7.5 1.8 3.7 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 ABC_membrane_2 PF06472.15 OAG07056.1 - 1.8e-103 345.6 1.2 3.1e-103 344.9 1.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAG07056.1 - 6.1e-18 65.7 0.0 1.2e-17 64.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAG07056.1 - 6.2e-05 22.9 0.0 0.00026 20.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAG07056.1 - 0.004 17.7 0.2 0.016 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG07056.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 OAG07056.1 - 0.052 13.0 0.2 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 OAG07056.1 - 0.095 12.1 0.1 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 OAG07056.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAG07056.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 OAG07056.1 - 0.17 12.3 2.3 0.91 9.9 0.1 2.7 3 0 0 3 3 3 0 AAA ATPase domain DUF1751 PF08551.10 OAG07058.1 - 2.1e-28 98.8 3.0 4.1e-28 97.9 3.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) LisH PF08513.11 OAG07059.1 - 0.00014 21.7 0.3 0.00028 20.7 0.3 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 OAG07059.1 - 0.0046 16.9 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OAG07059.1 - 0.063 14.2 2.9 3.8 8.5 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat FMO-like PF00743.19 OAG07060.1 - 7.4e-12 44.5 0.2 8.1e-11 41.0 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG07060.1 - 2.5e-09 36.8 0.0 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG07060.1 - 8.6e-09 35.1 0.0 0.00011 21.6 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG07060.1 - 5.6e-08 32.3 0.1 8.3e-06 25.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG07060.1 - 1.3e-07 31.7 0.3 4e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG07060.1 - 7.3e-05 22.5 0.1 0.0021 17.7 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG07060.1 - 8.5e-05 22.6 0.0 0.019 14.9 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG07060.1 - 0.0086 15.3 0.0 0.044 13.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OAG07060.1 - 0.024 13.3 0.1 0.049 12.3 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAG07060.1 - 0.22 10.6 0.0 6.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Ank_2 PF12796.7 OAG07061.1 - 1.3e-33 115.5 10.7 1.3e-07 32.1 0.1 11.2 8 3 3 11 11 11 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG07061.1 - 6.1e-17 61.8 15.4 0.079 13.6 0.0 12.8 11 2 2 13 13 13 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG07061.1 - 5.1e-14 51.0 7.4 0.2 12.3 0.0 13.8 20 0 0 20 20 20 2 Ankyrin repeat Ank_5 PF13857.6 OAG07061.1 - 3.8e-13 49.4 12.0 0.00016 21.9 0.0 9.6 9 0 0 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG07061.1 - 1.8e-11 43.9 21.9 0.43 11.1 0.0 13.4 14 1 0 14 14 14 3 Ankyrin repeat DUF3455 PF11937.8 OAG07063.1 - 9.1e-41 139.9 1.4 1.1e-40 139.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Malate_synthase PF01274.22 OAG07064.1 - 6e-228 757.4 0.0 6.8e-228 757.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF1929 PF09118.11 OAG07066.1 - 1.7e-23 82.7 0.6 3.8e-23 81.6 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 OAG07066.1 - 3.2e-17 62.1 0.5 3e-05 24.1 0.0 4.9 3 1 1 4 4 4 3 Kelch motif PAN_1 PF00024.26 OAG07066.1 - 2.5e-15 56.2 4.2 7.2e-07 29.1 1.1 2.4 2 0 0 2 2 2 2 PAN domain Kelch_1 PF01344.25 OAG07066.1 - 1.5e-10 40.5 0.0 0.0084 15.7 0.0 4.1 3 1 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 OAG07066.1 - 1.2e-07 31.7 7.3 0.004 17.1 0.1 5.5 5 2 0 5 5 5 3 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 OAG07066.1 - 4.5e-07 29.3 0.0 0.0041 16.3 0.0 3.1 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 OAG07066.1 - 6.5e-07 29.1 0.1 0.048 13.6 0.0 4.8 5 1 0 5 5 5 2 Kelch motif PAN_4 PF14295.6 OAG07066.1 - 5.1e-06 26.3 5.0 0.041 13.8 0.3 2.7 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 OAG07066.1 - 0.00073 19.8 5.9 0.24 11.7 0.8 2.3 2 0 0 2 2 2 2 MANEC domain PAN_3 PF08277.12 OAG07066.1 - 1.5 8.6 8.6 3.5 7.5 0.6 2.4 2 0 0 2 2 2 0 PAN-like domain HSF_DNA-bind PF00447.17 OAG07067.1 - 4.6e-19 68.8 0.4 9.3e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding zf-C2H2_2 PF12756.7 OAG07067.1 - 0.023 15.0 0.6 0.062 13.6 0.6 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 OAG07067.1 - 0.11 12.9 3.4 11 6.5 0.5 3.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Cnl2_NKP2 PF09447.10 OAG07069.1 - 1.6e-21 76.2 0.0 2.9e-20 72.2 0.0 2.4 2 0 0 2 2 2 1 Cnl2/NKP2 family protein DUF4407 PF14362.6 OAG07069.1 - 0.019 14.3 2.2 0.024 14.0 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IMD PF08397.11 OAG07069.1 - 0.053 12.9 0.5 0.069 12.5 0.5 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Mod_r PF07200.13 OAG07069.1 - 0.077 13.1 0.4 0.17 12.0 0.4 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Osmo_CC PF08946.10 OAG07069.1 - 1.4 9.2 5.4 0.49 10.7 0.5 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil MRG PF05712.13 OAG07070.1 - 1.2e-49 168.3 0.1 2.1e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 OAG07070.1 - 5.7e-09 35.7 3.8 1.1e-08 34.8 3.8 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Ribosomal_L32e PF01655.18 OAG07070.1 - 0.025 15.0 0.3 0.39 11.2 0.1 2.2 1 1 1 2 2 2 0 Ribosomal protein L32 Chromo PF00385.24 OAG07070.1 - 0.064 13.2 3.6 0.13 12.1 3.6 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_18 PF13238.6 OAG07071.1 - 0.00024 21.6 0.0 0.0007 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG07071.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG07071.1 - 0.0044 17.5 0.0 0.0073 16.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PRK PF00485.18 OAG07071.1 - 0.0078 16.0 0.0 0.052 13.3 0.0 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 OAG07071.1 - 0.049 14.0 0.0 0.066 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 OAG07071.1 - 0.093 12.5 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 OAG07071.1 - 0.094 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1741 PF08427.10 OAG07072.1 - 5.3e-80 268.4 0.1 1.4e-79 267.1 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1741) Dymeclin PF09742.9 OAG07072.1 - 0.0034 15.9 0.1 0.0077 14.7 0.1 1.5 2 0 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein DUF1479 PF07350.12 OAG07074.1 - 2.8e-119 398.6 0.0 3.4e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sulf_transp PF04143.14 OAG07075.1 - 9.9e-07 28.6 16.2 5.3e-06 26.2 2.3 3.0 2 1 1 3 3 3 2 Sulphur transport gag-asp_proteas PF13975.6 OAG07076.1 - 1.6e-14 54.2 0.0 3e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAG07076.1 - 1.3e-12 48.2 0.1 2.7e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.10 OAG07076.1 - 0.0018 18.0 0.0 0.052 13.3 0.0 2.2 1 1 1 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 OAG07076.1 - 0.0045 16.7 0.0 0.84 9.4 0.0 2.3 2 0 0 2 2 2 2 Retroviral aspartyl protease MRG PF05712.13 OAG07077.1 - 0.0067 15.8 0.1 0.013 14.9 0.1 1.4 1 1 0 1 1 1 1 MRG DoxX_2 PF13564.6 OAG07077.1 - 0.017 15.2 3.7 0.028 14.5 3.7 1.2 1 0 0 1 1 1 0 DoxX-like family YukC PF10140.9 OAG07077.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF4534 PF15049.6 OAG07077.1 - 0.078 12.7 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) DUF2417 PF10329.9 OAG07077.1 - 0.4 10.0 2.2 0.6 9.5 0.2 1.9 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF2723 PF11028.8 OAG07077.1 - 0.79 9.6 6.0 1.2 9.0 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) RIBIOP_C PF04950.12 OAG07078.1 - 5.6e-105 350.9 0.0 1.2e-104 349.9 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAG07078.1 - 2.5e-19 69.2 0.0 5.5e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Fe-S_biosyn PF01521.20 OAG07079.1 - 5.5e-17 62.0 0.0 7.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF4674 PF15719.5 OAG07079.1 - 1.3 9.0 4.1 10 6.1 4.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) Dabb PF07876.12 OAG07080.1 - 3.7e-24 85.2 0.0 4.1e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF2407_C PF13373.6 OAG07081.1 - 1.9e-39 135.1 0.1 2.8e-39 134.5 0.1 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 OAG07081.1 - 2.5e-31 108.3 0.0 4.8e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAG07081.1 - 2.6e-05 23.9 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF1455 PF07306.11 OAG07081.1 - 0.45 10.5 3.4 0.9 9.5 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) CAP_N PF01213.19 OAG07081.1 - 0.54 9.7 4.5 0.13 11.8 0.5 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ZapB PF06005.12 OAG07082.1 - 2.1e-05 24.9 5.0 2.7e-05 24.5 5.0 1.3 1 0 0 1 1 1 1 Cell division protein ZapB TPR_MLP1_2 PF07926.12 OAG07082.1 - 0.00059 19.9 2.7 0.00059 19.9 2.7 1.7 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 OAG07082.1 - 0.0033 16.8 3.1 0.0037 16.6 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.9 OAG07082.1 - 0.0036 17.3 0.7 0.0037 17.3 0.7 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Nup54 PF13874.6 OAG07082.1 - 0.011 15.9 0.8 0.012 15.7 0.8 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Cep57_CLD_2 PF14197.6 OAG07082.1 - 0.013 15.6 4.3 0.038 14.1 1.4 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 OAG07082.1 - 0.017 15.2 3.8 0.039 14.0 3.8 1.7 1 1 0 1 1 1 0 bZIP transcription factor HALZ PF02183.18 OAG07082.1 - 0.021 15.0 4.4 0.039 14.2 1.2 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper CLZ PF16526.5 OAG07082.1 - 0.047 14.0 3.1 0.063 13.7 3.1 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 OAG07082.1 - 0.051 13.6 0.2 0.061 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OAG07082.1 - 0.054 14.0 7.1 0.065 13.8 7.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 OAG07082.1 - 0.081 12.7 7.1 0.2 11.5 6.6 1.8 1 1 1 2 2 2 0 Septum formation initiator TSP_NTD PF17804.1 OAG07082.1 - 0.1 12.9 1.8 0.12 12.7 1.8 1.0 1 0 0 1 1 1 0 Tail specific protease N-terminal domain MRPL52 PF18699.1 OAG07082.1 - 0.11 12.7 3.7 0.13 12.5 3.7 1.1 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Spc24 PF08286.11 OAG07082.1 - 0.12 12.6 3.8 0.15 12.3 3.8 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 APC_N_CC PF16689.5 OAG07082.1 - 0.22 11.6 2.5 0.19 11.8 1.3 1.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain XhlA PF10779.9 OAG07082.1 - 0.27 11.4 4.0 0.38 11.0 4.0 1.2 1 0 0 1 1 1 0 Haemolysin XhlA Dzip-like_N PF13815.6 OAG07082.1 - 0.29 11.1 2.7 0.37 10.8 2.7 1.1 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Tup_N PF08581.10 OAG07082.1 - 0.34 11.2 4.5 0.66 10.3 4.5 1.5 1 1 0 1 1 1 0 Tup N-terminal JIP_LZII PF16471.5 OAG07082.1 - 0.39 10.9 5.7 2.7 8.2 0.2 2.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II NYD-SP28_assoc PF14775.6 OAG07082.1 - 0.76 9.9 3.0 0.26 11.4 0.5 1.7 2 1 0 2 2 1 0 Sperm tail C-terminal domain DUF2205 PF10224.9 OAG07082.1 - 3.3 7.8 6.9 2.1 8.4 1.2 2.1 1 1 1 2 2 2 0 Short coiled-coil protein Atg14 PF10186.9 OAG07083.1 - 0.18 10.9 19.6 0.21 10.7 19.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 OAG07083.1 - 0.27 9.7 2.1 0.3 9.6 2.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 OAG07083.1 - 6.4 6.8 19.6 7.7 6.6 19.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TACC_C PF05010.14 OAG07084.1 - 0.31 10.8 36.4 0.59 9.9 23.4 2.5 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 OAG07084.1 - 1.2 9.2 22.4 0.048 13.7 5.3 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OAG07084.1 - 1.5 7.7 41.2 1.7 7.5 13.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Fungal_trans_2 PF11951.8 OAG07087.1 - 5.8e-48 163.6 0.0 7.9e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07087.1 - 4.4e-08 33.1 6.2 8.4e-08 32.2 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 OAG07087.1 - 3.1 7.8 25.2 6.3 6.8 8.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein UvdE PF03851.14 OAG07089.1 - 2.9e-113 377.7 0.0 3.7e-113 377.4 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Troponin-I_N PF11636.8 OAG07089.1 - 0.0076 16.2 1.4 0.0076 16.2 1.4 3.9 4 0 0 4 4 4 2 Troponin I residues 1-32 Amidohydro_3 PF07969.11 OAG07091.1 - 2.2e-08 34.0 0.3 0.00014 21.5 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 OAG07091.1 - 1.7e-05 24.3 0.0 2.7e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family C2 PF00168.30 OAG07092.1 - 6.9e-28 97.0 0.0 6e-17 61.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain SR-25 PF10500.9 OAG07092.1 - 4.8 6.7 17.4 0.16 11.6 8.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sugar_tr PF00083.24 OAG07093.1 - 4.6e-83 279.6 17.4 5.4e-83 279.4 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07093.1 - 9e-21 74.2 33.5 1e-16 60.9 5.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 OAG07094.1 - 5e-66 223.0 0.0 8e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG07094.1 - 2.7e-05 25.0 0.0 7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2 PF00096.26 OAG07095.1 - 2.9e-11 43.1 28.7 0.015 15.8 1.2 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG07095.1 - 2.8e-09 37.0 29.4 0.14 13.0 0.1 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG07095.1 - 5.7e-07 29.7 9.9 0.0042 17.5 0.1 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 OAG07095.1 - 0.00018 21.8 24.0 0.54 10.7 2.4 5.9 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG07095.1 - 0.00022 21.4 22.1 0.32 11.3 0.1 5.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG07095.1 - 0.00037 20.4 23.0 0.11 12.5 0.2 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf_UBZ PF18439.1 OAG07095.1 - 0.0098 15.5 5.1 0.12 12.0 0.2 3.3 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-RRN7 PF11781.8 OAG07095.1 - 0.045 13.4 6.7 0.33 10.7 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RNA_POL_M_15KD PF02150.16 OAG07095.1 - 0.15 12.0 1.0 0.44 10.5 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_15 PF17032.5 OAG07095.1 - 0.17 12.6 5.6 3.5 8.4 1.7 3.1 2 1 0 2 2 2 0 zinc-ribbon family Vps36-NZF-N PF16988.5 OAG07095.1 - 0.25 10.8 4.7 0.66 9.4 1.6 3.0 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_2 PF12756.7 OAG07095.1 - 2.2 8.6 15.5 1.2 9.5 0.3 4.6 4 1 2 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OAG07095.1 - 3.7 7.4 16.2 0.12 12.2 1.2 4.0 4 0 0 4 4 4 0 zinc-finger C2H2-type HypA PF01155.19 OAG07095.1 - 5.4 7.1 7.5 8.4 6.5 0.5 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-C2H2_12 PF18112.1 OAG07095.1 - 8.3 7.0 8.6 5.9 7.5 0.5 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain His_Phos_1 PF00300.22 OAG07096.1 - 2.4e-34 118.7 2.6 1.7e-31 109.5 2.6 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cellulase PF00150.18 OAG07097.1 - 1.1e-49 169.4 0.1 1.4e-49 169.0 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DNA_methylase PF00145.17 OAG07098.1 - 5.5e-34 118.0 0.0 1.3e-23 83.9 0.0 2.3 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase DUF1690 PF07956.11 OAG07099.1 - 5.5e-33 114.3 18.0 1.9e-31 109.3 18.0 2.0 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 OAG07099.1 - 0.004 17.2 14.1 0.007 16.4 14.1 1.3 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Matrilin_ccoil PF10393.9 OAG07099.1 - 0.004 17.0 6.3 0.8 9.6 0.3 3.4 3 0 0 3 3 3 2 Trimeric coiled-coil oligomerisation domain of matrilin DUF3631 PF12307.8 OAG07099.1 - 0.022 15.0 4.3 0.081 13.1 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3631) Exonuc_VII_L PF02601.15 OAG07099.1 - 0.089 12.3 7.5 0.11 12.1 7.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LCD1 PF09798.9 OAG07099.1 - 0.091 11.3 12.0 0.11 11.1 12.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF2894 PF11445.8 OAG07099.1 - 0.14 12.6 9.1 0.18 12.2 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) ATG16 PF08614.11 OAG07099.1 - 0.82 9.9 21.3 2.9 8.0 21.6 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 OAG07099.1 - 0.96 8.7 10.3 1.3 8.3 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 OAG07099.1 - 1.2 9.8 11.6 0.074 13.7 1.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Goodbye PF17109.5 OAG07099.1 - 7.8 7.0 8.6 2.5 8.5 0.8 2.5 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain PRKG1_interact PF15898.5 OAG07099.1 - 9.4 7.2 16.4 0.53 11.2 4.6 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Acetyltransf_1 PF00583.25 OAG07100.1 - 1.2e-11 44.9 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG07100.1 - 2.2e-05 24.4 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG07100.1 - 3.2e-05 24.3 0.0 4.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG07100.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 OAG07100.1 - 0.039 13.9 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.7 OAG07100.1 - 0.23 11.6 0.0 0.32 11.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CBM_1 PF00734.18 OAG07101.1 - 1.7e-08 34.3 12.6 5.1e-08 32.7 12.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Stm1_N PF09598.10 OAG07101.1 - 4.8 8.1 9.7 10 7.1 9.7 1.6 1 1 0 1 1 1 0 Stm1 RasGEF PF00617.19 OAG07103.1 - 2.4e-43 148.4 0.0 4e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG07103.1 - 1.5e-10 41.2 0.0 4.5e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 OAG07103.1 - 2.6e-05 23.9 0.0 8.6e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.27 OAG07103.1 - 0.0002 21.9 0.0 0.082 13.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 OAG07103.1 - 0.0094 16.3 0.0 0.04 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAG07103.1 - 0.015 15.4 0.1 0.079 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAG07103.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 OAG07103.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain COX6B PF02297.17 OAG07105.1 - 2.6e-19 69.2 2.5 3.1e-19 69.0 2.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 OAG07105.1 - 0.0026 17.7 0.9 0.0042 17.1 0.9 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ketoacyl-synt PF00109.26 OAG07105.1 - 0.026 14.1 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain APOBEC_C PF05240.14 OAG07105.1 - 0.028 14.4 0.2 0.037 14.0 0.2 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain B12D PF06522.11 OAG07106.1 - 0.048 13.5 0.1 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 OAG07107.1 - 7.1e-17 61.0 0.0 1.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG07107.1 - 0.00056 20.0 0.0 0.00078 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OAG07107.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OAG07107.1 - 0.12 11.9 0.0 0.33 10.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRA1 PF07304.11 OAG07108.1 - 5.4e-09 36.0 0.2 5.4e-09 36.0 0.2 3.5 2 2 1 3 3 3 1 Steroid receptor RNA activator (SRA1) ANAPC4_WD40 PF12894.7 OAG07108.1 - 0.0005 20.3 0.0 0.022 15.0 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.7 OAG07108.1 - 0.011 15.4 1.8 0.2 11.3 0.9 2.7 2 1 0 2 2 2 0 Sec23-binding domain of Sec16 Prp18 PF02840.15 OAG07108.1 - 0.014 15.5 3.3 0.018 15.1 0.2 2.4 2 1 0 2 2 2 0 Prp18 domain Herpes_DNAp_acc PF04929.12 OAG07109.1 - 4.6 6.1 19.2 1.9 7.3 17.0 1.3 1 1 0 1 1 1 0 Herpes DNA replication accessory factor Acetyltransf_1 PF00583.25 OAG07110.1 - 0.0034 17.6 0.0 0.0073 16.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG07110.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ParG PF09274.10 OAG07110.1 - 0.051 13.7 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 ParG Acetyltransf_7 PF13508.7 OAG07110.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 OAG07111.1 - 0.00021 21.3 5.2 0.00044 20.3 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 OAG07112.1 - 1.9e-27 96.7 0.0 2.6e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Rsd_AlgQ PF04353.13 OAG07113.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Fungal_trans PF04082.18 OAG07114.1 - 9.7e-23 80.5 0.1 2e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07114.1 - 7.7e-09 35.5 8.5 1.4e-08 34.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SgrT PF15894.5 OAG07114.1 - 0.34 10.9 1.1 1.1 9.3 0.2 2.3 3 0 0 3 3 3 0 Inhibitor of glucose uptake transporter SgrT Neugrin PF06413.11 OAG07115.1 - 2e-12 47.6 0.8 3.4e-12 46.9 0.8 1.4 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 OAG07115.1 - 1.1e-05 25.7 4.8 2e-05 24.8 4.8 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF2236 PF09995.9 OAG07116.1 - 9.6e-35 120.8 0.1 1.5e-34 120.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Torus PF16131.5 OAG07117.1 - 0.00053 20.7 1.4 0.0064 17.2 0.1 2.7 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 OAG07117.1 - 0.00069 19.6 5.9 0.0017 18.4 5.9 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAG07117.1 - 0.018 15.0 2.8 0.041 13.8 2.8 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 OAG07117.1 - 0.16 12.2 4.3 0.24 11.6 3.0 2.0 2 1 0 2 2 2 0 Zinc-finger containing family adh_short PF00106.25 OAG07118.1 - 1.4e-26 93.2 0.0 1.7e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07118.1 - 1.9e-19 70.2 0.2 2.4e-19 69.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07118.1 - 1.3e-07 31.7 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG07118.1 - 0.00029 20.4 0.1 0.00069 19.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG07118.1 - 0.0015 18.4 0.0 0.005 16.8 0.0 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Halo_GVPC PF05465.13 OAG07118.1 - 0.12 12.6 0.4 0.33 11.3 0.4 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Cytochrom_C PF00034.21 OAG07119.1 - 5.9e-11 43.4 0.1 7.9e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OAG07119.1 - 3.1e-08 33.8 1.3 1.3e-07 31.8 1.3 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OAG07119.1 - 0.0049 16.6 1.6 0.023 14.4 1.6 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain BCDHK_Adom3 PF10436.9 OAG07120.1 - 6e-75 250.5 0.0 8.5e-75 250.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAG07120.1 - 7.9e-13 48.9 0.0 1.8e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG07120.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LTD PF00932.19 OAG07121.1 - 0.34 11.3 4.7 2.1 8.7 0.7 3.6 2 1 1 3 3 3 0 Lamin Tail Domain EHN PF06441.12 OAG07122.1 - 3.6e-29 101.3 0.5 3.6e-27 94.9 0.1 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG07122.1 - 3.2e-18 66.3 0.1 5.1e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG07122.1 - 2.1e-10 41.6 0.3 3.3e-10 40.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG07122.1 - 0.0055 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAG07122.1 - 0.18 10.7 0.1 0.43 9.4 0.1 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme DAG_kinase_N PF14513.6 OAG07123.1 - 0.048 13.9 0.0 0.086 13.0 0.0 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Glyco_hydro_61 PF03443.14 OAG07124.1 - 1.2e-48 165.8 0.0 1.4e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Amidohydro_1 PF01979.20 OAG07125.1 - 2.5e-53 181.6 0.0 3.7e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG07125.1 - 1.6e-13 51.0 3.1 1.1e-10 41.6 0.1 2.7 3 0 0 3 3 3 2 Amidohydrolase family VSP PF03302.13 OAG07126.1 - 0.029 13.3 0.9 0.039 12.8 0.9 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein TetR_C_32 PF09209.11 OAG07126.1 - 0.11 12.5 0.1 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FAA_hydro_N_2 PF18288.1 OAG07127.1 - 0.033 14.6 0.1 0.057 13.8 0.1 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 PLC-beta_C PF08703.10 OAG07127.1 - 0.073 13.0 4.6 0.097 12.6 4.6 1.1 1 0 0 1 1 1 0 PLC-beta C terminal TPR_MLP1_2 PF07926.12 OAG07127.1 - 0.087 12.9 6.4 0.12 12.5 6.4 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4337 PF14235.6 OAG07127.1 - 0.28 11.3 6.3 0.19 11.9 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DASH_Hsk3 PF08227.11 OAG07128.1 - 8.4e-18 64.5 1.9 1.2e-17 64.0 1.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like ADIP PF11559.8 OAG07128.1 - 0.004 17.2 0.1 0.0051 16.9 0.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding FlxA PF14282.6 OAG07128.1 - 0.0068 16.4 1.9 0.0094 15.9 1.9 1.2 1 0 0 1 1 1 1 FlxA-like protein SlyX PF04102.12 OAG07128.1 - 0.015 15.9 0.6 0.023 15.3 0.6 1.4 1 0 0 1 1 1 0 SlyX GATA PF00320.27 OAG07130.1 - 4.2e-16 58.3 2.5 7.9e-16 57.4 2.5 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 OAG07130.1 - 2e-12 46.7 2.6 3.6e-12 45.9 2.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Prok-E2_A PF14457.6 OAG07130.1 - 0.007 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family A DJ-1_PfpI PF01965.24 OAG07131.1 - 2.1e-40 138.2 0.0 2.5e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG07131.1 - 0.00024 20.8 0.0 0.013 15.2 0.0 2.1 1 1 1 2 2 2 2 ThiJ/PfpI family-like GATase_3 PF07685.14 OAG07131.1 - 0.003 17.2 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 OAG07132.1 - 2.3e-26 92.6 30.0 2.3e-26 92.6 30.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 OAG07133.1 - 1.9e-18 66.8 0.1 3.2e-18 66.1 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG07133.1 - 1.4e-08 34.4 1.0 0.00016 21.0 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG07133.1 - 3.6e-08 33.4 7.6 0.00015 21.5 4.5 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG07133.1 - 1.3e-06 28.5 0.6 3.1e-06 27.3 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG07133.1 - 1.4e-06 27.7 3.1 2.7e-06 26.7 3.1 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG07133.1 - 9.3e-06 24.9 1.6 2e-05 23.8 1.6 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 OAG07133.1 - 1.4e-05 24.1 4.7 0.056 12.3 0.9 3.1 2 1 1 3 3 3 3 Tryptophan halogenase Pyr_redox PF00070.27 OAG07133.1 - 0.00015 22.2 1.7 0.0024 18.4 2.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG07133.1 - 0.00016 21.0 0.6 0.00026 20.3 0.6 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG07133.1 - 0.00021 20.8 2.7 0.00034 20.1 2.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG07133.1 - 0.0062 15.3 1.2 0.0062 15.3 1.2 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG07133.1 - 0.0063 15.6 3.4 0.0097 15.0 3.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG07133.1 - 0.085 12.1 1.0 0.13 11.4 1.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 OAG07133.1 - 0.18 11.7 1.7 0.22 11.4 0.3 1.8 2 0 0 2 2 2 0 Rossmann-like domain 3HCDH_N PF02737.18 OAG07133.1 - 0.19 11.6 2.0 0.35 10.7 2.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 OAG07133.1 - 0.3 10.3 1.7 0.42 9.8 0.5 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 OAG07134.1 - 1.9e-32 112.3 0.3 4e-32 111.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07134.1 - 1.9e-10 40.7 9.0 4.7e-10 39.4 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.11 OAG07135.1 - 5.1e-26 90.2 0.6 7.9e-17 60.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG07135.1 - 6.4e-08 32.6 0.7 0.012 15.5 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG07135.1 - 2.5e-06 27.1 0.0 0.048 13.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 OAG07135.1 - 6.8e-05 23.0 0.0 0.00025 21.2 0.0 1.8 2 0 0 2 2 2 1 Mif2/CENP-C like DMSP_lyase PF16867.5 OAG07135.1 - 0.013 15.1 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase ARD PF03079.14 OAG07135.1 - 0.11 12.6 0.0 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family FAA_hydrolase PF01557.18 OAG07136.1 - 5.6e-57 192.9 0.0 7.4e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RPE65 PF03055.15 OAG07137.1 - 2e-104 350.4 0.0 2.3e-104 350.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3328 PF11807.8 OAG07138.1 - 4.8e-39 134.4 1.7 6.1e-39 134.1 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF924 PF06041.11 OAG07139.1 - 1.2e-42 146.1 0.0 1.4e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) HET PF06985.11 OAG07140.1 - 2.8e-28 99.1 0.1 6.2e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_30C PF17189.4 OAG07142.1 - 5.2e-10 39.4 0.6 1.1e-09 38.4 0.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 OAG07142.1 - 8.4e-08 31.6 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 OAG07142.1 - 2.5e-06 26.9 0.0 3.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 OAG07142.1 - 0.0035 17.0 0.0 0.0093 15.6 0.0 1.6 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 adh_short PF00106.25 OAG07143.1 - 0.00032 20.2 0.0 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Peptidase_C97 PF05903.14 OAG07144.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain DUF4105 PF13387.6 OAG07144.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) LRAT PF04970.13 OAG07144.1 - 0.17 12.2 0.3 1.4 9.3 0.0 2.2 1 1 0 2 2 2 0 Lecithin retinol acyltransferase Sugar_tr PF00083.24 OAG07145.1 - 1.6e-76 258.0 16.8 2.4e-76 257.4 16.8 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07145.1 - 4.3e-18 65.4 41.0 1.8e-11 43.6 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4264 PF14084.6 OAG07146.1 - 1 9.1 5.4 98 2.7 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF4264) Glyco_hydro_61 PF03443.14 OAG07147.1 - 1.5e-52 178.5 0.1 1.9e-52 178.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fasciclin PF02469.22 OAG07148.1 - 1.2e-42 145.2 4.3 5e-22 78.5 1.5 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF2950 PF11453.8 OAG07148.1 - 0.21 10.8 0.0 0.47 9.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Peptidase_S9 PF00326.21 OAG07149.1 - 5.7e-11 42.3 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAG07149.1 - 1.8e-10 41.0 0.5 5.5e-10 39.5 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAG07149.1 - 1.1e-07 31.6 0.0 2.9e-05 23.8 0.0 2.9 3 1 0 3 3 3 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAG07149.1 - 6.3e-05 22.3 0.1 0.17 11.1 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAG07149.1 - 0.0031 17.3 0.0 1.9 8.2 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 OAG07149.1 - 0.0064 16.2 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 OAG07149.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 OAG07149.1 - 0.09 12.3 0.5 0.41 10.1 0.4 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase FSH1 PF03959.13 OAG07149.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Kelch_5 PF13854.6 OAG07150.1 - 1.2e-12 47.5 20.7 3.2e-11 42.9 0.4 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 OAG07150.1 - 3.1e-07 30.3 18.0 0.0015 18.5 0.0 6.1 6 0 0 6 6 6 2 Galactose oxidase, central domain SKG6 PF08693.10 OAG07150.1 - 0.0021 17.4 0.2 0.0038 16.6 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.25 OAG07150.1 - 0.013 15.1 12.1 0.71 9.5 0.0 5.6 6 0 0 6 6 6 0 Kelch motif Kelch_6 PF13964.6 OAG07150.1 - 0.027 14.8 19.3 0.1 12.9 0.1 5.2 5 1 1 6 6 6 0 Kelch motif Kelch_2 PF07646.15 OAG07150.1 - 0.035 14.1 11.3 18 5.5 0.4 6.1 6 0 0 6 6 6 0 Kelch motif Syndecan PF01034.20 OAG07150.1 - 0.059 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OAG07150.1 - 0.063 14.2 0.0 0.38 11.7 0.0 2.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 OAG07150.1 - 0.23 11.0 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family AF-4 PF05110.13 OAG07151.1 - 0.4 8.7 5.4 0.49 8.4 5.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CFEM PF05730.11 OAG07151.1 - 0.67 10.1 9.6 1.1 9.4 9.1 1.6 1 1 0 1 1 1 0 CFEM domain MFS_1 PF07690.16 OAG07153.1 - 5.6e-11 42.0 42.1 5.6e-11 42.0 42.1 3.7 2 2 1 3 3 3 2 Major Facilitator Superfamily IMUP PF15761.5 OAG07153.1 - 0.024 15.3 9.9 0.065 13.9 9.9 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein Thiolase_N PF00108.23 OAG07154.1 - 4.3e-14 52.5 0.0 1.3e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG07154.1 - 9.6e-11 41.4 0.3 6e-10 38.8 0.4 2.3 1 1 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG07154.1 - 1.3e-05 25.0 0.4 0.0014 18.4 0.0 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG07154.1 - 7.1e-05 22.5 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAG07154.1 - 0.027 14.5 0.3 0.41 10.7 0.3 2.8 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SmaI PF17411.2 OAG07154.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease MFS_1 PF07690.16 OAG07155.1 - 1.2e-40 139.5 36.4 3.2e-35 121.7 25.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG07155.1 - 2.9e-08 33.4 15.0 1.6e-05 24.4 4.2 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAG07155.1 - 1.6e-05 23.4 3.1 1.6e-05 23.4 3.1 2.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 OAG07155.1 - 1.7e-05 23.6 24.1 0.00034 19.3 9.0 3.1 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 OAG07155.1 - 2.7e-05 23.2 25.1 5.8e-05 22.1 16.1 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG07155.1 - 0.0002 20.3 20.7 0.28 10.0 0.7 4.3 3 1 1 4 4 4 4 MFS_1 like family Polysacc_synt_3 PF13440.6 OAG07155.1 - 0.024 13.8 0.9 0.055 12.7 0.4 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein LacY_symp PF01306.19 OAG07155.1 - 0.027 13.3 0.2 0.027 13.3 0.2 2.6 3 0 0 3 3 3 0 LacY proton/sugar symporter Peptidase_U4 PF03419.13 OAG07155.1 - 0.2 10.9 2.1 1 8.6 2.1 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF2304 PF10066.9 OAG07155.1 - 0.29 11.4 5.2 0.12 12.5 0.4 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) MFS_1 PF07690.16 OAG07156.1 - 1.2e-16 60.6 43.6 9.7e-11 41.2 11.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Rad52_Rad22 PF04098.15 OAG07157.1 - 1.1e-59 200.7 0.1 1.5e-59 200.3 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein CDK2AP PF09806.9 OAG07157.1 - 0.6 10.1 4.9 1 9.3 4.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.13 OAG07157.1 - 2.2 8.2 14.7 3.1 7.7 14.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S10 PF00450.22 OAG07158.1 - 8.4e-117 391.1 0.0 1.1e-116 390.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MSP1b PF03429.13 OAG07158.1 - 0.15 10.1 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B RNA_Me_trans PF04252.13 OAG07159.1 - 2.7e-82 275.2 0.0 3e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.17 OAG07160.1 - 5.8e-29 100.1 0.1 9e-29 99.4 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region WD40 PF00400.32 OAG07161.1 - 4.2e-25 87.5 9.4 1.2e-06 29.1 0.4 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG07161.1 - 1.4e-13 51.0 0.5 2.3e-05 24.6 0.0 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG07161.1 - 0.028 13.7 0.0 7.4 5.8 0.0 3.0 2 1 0 2 2 2 0 WD40-like domain Nbas_N PF15492.6 OAG07161.1 - 0.029 13.7 0.4 4.5 6.5 0.0 3.2 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 OAG07161.1 - 0.035 12.6 0.1 2 6.8 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 OAG07161.1 - 0.14 11.1 0.4 0.41 9.5 0.2 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 OAG07161.1 - 0.17 10.8 0.1 5.8 5.8 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4331 PF14224.6 OAG07161.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) Guanylate_kin PF00625.21 OAG07162.1 - 4.7e-62 208.9 0.0 5.4e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 OAG07162.1 - 2.3e-05 24.8 0.1 3.8e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAG07162.1 - 4.4e-05 23.7 0.1 0.00034 20.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG07162.1 - 9.2e-05 23.0 0.1 0.00041 20.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG07162.1 - 0.00017 21.9 0.0 0.00035 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAG07162.1 - 0.0009 18.4 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.15 OAG07162.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.27 OAG07162.1 - 0.0011 19.5 0.0 0.0012 19.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 OAG07162.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OAG07162.1 - 0.0021 18.2 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OAG07162.1 - 0.0025 17.5 0.2 0.0044 16.7 0.2 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 OAG07162.1 - 0.0027 17.4 0.6 0.39 10.4 0.6 2.4 1 1 0 1 1 1 1 Thymidylate kinase Rad17 PF03215.15 OAG07162.1 - 0.0032 17.4 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 OAG07162.1 - 0.0043 17.5 0.1 0.18 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAG07162.1 - 0.0058 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OAG07162.1 - 0.0058 16.9 0.0 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG07162.1 - 0.006 17.0 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 OAG07162.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OAG07162.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase dNK PF01712.19 OAG07162.1 - 0.0096 15.8 0.1 0.17 11.7 0.0 2.4 2 1 1 3 3 3 1 Deoxynucleoside kinase NACHT PF05729.12 OAG07162.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 OAG07162.1 - 0.015 14.9 0.0 0.099 12.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OAG07162.1 - 0.018 15.0 0.1 0.029 14.3 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 OAG07162.1 - 0.026 13.8 0.0 0.59 9.3 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 OAG07162.1 - 0.028 14.1 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OAG07162.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain Gtr1_RagA PF04670.12 OAG07162.1 - 0.052 12.9 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Cytidylate_kin PF02224.18 OAG07162.1 - 0.053 13.3 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase Viral_helicase1 PF01443.18 OAG07162.1 - 0.055 13.2 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ADK PF00406.22 OAG07162.1 - 0.076 13.1 0.1 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.14 OAG07162.1 - 0.15 12.1 0.4 0.78 9.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 OAG07162.1 - 0.15 12.6 1.5 0.2 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 OAG07162.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein WD40 PF00400.32 OAG07163.1 - 3.3e-16 59.4 7.1 0.005 17.6 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG07163.1 - 2.5e-11 43.7 0.1 1.6e-06 28.3 0.0 4.5 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG07163.1 - 0.00055 19.0 0.5 0.053 12.5 0.0 3.3 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 OAG07163.1 - 0.037 13.4 0.2 5.1 6.3 0.0 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.7 OAG07163.1 - 0.095 12.6 0.1 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term AMPK1_CBM PF16561.5 OAG07163.1 - 0.1 12.9 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Erythro-docking PF09277.11 OAG07164.1 - 0.087 12.7 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 Erythronolide synthase, docking CRM1_C PF08767.11 OAG07165.1 - 3.2e-134 447.1 1.7 3.2e-134 447.1 1.7 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 OAG07165.1 - 1.3e-39 135.6 7.3 4.2e-39 134.0 2.1 3.7 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OAG07165.1 - 3.6e-34 116.2 1.9 1.2e-33 114.5 1.9 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OAG07165.1 - 2.9e-29 100.9 0.7 2.9e-29 100.9 0.7 3.2 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OAG07165.1 - 2.3e-20 71.8 1.0 5.4e-20 70.6 1.0 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OAG07165.1 - 4.2e-14 52.2 0.1 2.2e-13 49.9 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 OAG07165.1 - 0.064 13.9 0.2 20 5.9 0.0 4.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Pre-PUA PF17832.1 OAG07165.1 - 0.072 13.8 0.0 0.43 11.3 0.0 2.3 1 0 0 1 1 1 0 Pre-PUA-like domain DRE2_N PF16803.5 OAG07165.1 - 0.13 12.5 0.1 2.5 8.4 0.0 2.8 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus DUF3385 PF11865.8 OAG07165.1 - 0.24 11.3 0.0 0.24 11.3 0.0 4.1 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 OAG07165.1 - 0.38 9.8 5.9 0.34 10.0 0.5 3.3 3 2 0 3 3 3 0 RNAPII transcription regulator C-terminal Orthopox_A49R PF06489.11 OAG07165.1 - 0.53 10.5 5.6 0.7 10.1 0.3 3.8 5 0 0 5 5 4 0 Orthopoxvirus A49R protein ABC1 PF03109.16 OAG07166.1 - 1e-34 119.2 0.0 1.7e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 OAG07166.1 - 0.096 12.3 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 RIO1 family HECT PF00632.25 OAG07167.1 - 1.4e-96 323.6 0.0 1.9e-96 323.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OAG07167.1 - 1e-33 115.1 22.7 3.7e-12 46.1 3.3 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 OAG07167.1 - 2.5e-20 72.7 0.0 6.8e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Sugar_tr PF00083.24 OAG07169.1 - 3.3e-143 477.8 23.2 3.9e-143 477.6 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07169.1 - 3.6e-22 78.8 33.8 3.7e-21 75.5 29.6 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF4579 PF15158.6 OAG07169.1 - 0.071 12.9 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) DUF962 PF06127.11 OAG07169.1 - 0.12 12.5 0.3 0.71 10.0 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF962) DUF2953 PF11167.8 OAG07169.1 - 8.7 6.5 11.6 4.6 7.4 0.1 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2953) BTB PF00651.31 OAG07170.1 - 0.045 14.0 0.1 0.65 10.3 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain adh_short_C2 PF13561.6 OAG07171.1 - 5.2e-32 111.3 0.6 8.9e-32 110.5 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG07171.1 - 5.3e-24 84.8 0.1 1.1e-23 83.7 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG07171.1 - 0.011 15.6 0.2 0.022 14.7 0.2 1.6 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 OAG07171.1 - 0.011 15.2 0.2 0.31 10.5 0.2 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DHquinase_I PF01487.15 OAG07172.1 - 2.6e-44 152.2 0.0 3.9e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 OAG07172.1 - 0.028 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain Fungal_trans PF04082.18 OAG07173.1 - 4.5e-23 81.6 0.3 9.7e-23 80.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07173.1 - 2.3e-06 27.6 16.6 3.9e-06 26.9 16.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.9 OAG07173.1 - 0.0014 18.0 11.4 0.0014 18.0 11.4 1.6 2 0 0 2 2 2 1 RAM signalling pathway protein Pyr_redox_2 PF07992.14 OAG07174.1 - 2.3e-61 207.6 0.6 4.1e-61 206.8 0.6 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAG07174.1 - 1.5e-32 112.2 0.5 3.8e-32 110.8 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAG07174.1 - 1.3e-16 60.9 0.8 1.9e-15 57.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG07174.1 - 4.4e-12 45.9 3.7 1.1e-11 44.6 3.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG07174.1 - 8e-08 31.8 0.3 0.0015 17.7 0.2 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 OAG07174.1 - 8.5e-06 25.4 0.3 0.00086 18.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OAG07174.1 - 9.1e-05 22.2 0.6 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG07174.1 - 0.00015 21.0 2.3 0.064 12.3 1.3 3.1 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 OAG07174.1 - 0.0041 15.9 4.1 0.89 8.2 0.3 2.9 2 1 1 3 3 3 2 HI0933-like protein GIDA PF01134.22 OAG07174.1 - 0.01 15.0 1.2 0.026 13.6 0.6 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 OAG07174.1 - 0.052 12.8 0.4 0.11 11.7 0.2 1.7 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 OAG07174.1 - 0.093 12.1 0.7 5.7 6.3 0.1 3.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAG07174.1 - 0.16 11.0 0.2 0.67 8.9 0.2 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Arabinose_trans PF04602.12 OAG07175.1 - 0.0038 16.1 0.0 0.0046 15.8 0.0 1.0 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Mito_carr PF00153.27 OAG07176.1 - 1.2e-41 140.6 6.6 7.9e-15 54.6 0.2 4.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4633 PF15464.6 OAG07176.1 - 0.02 15.0 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Leuk-A4-hydro_C PF09127.11 OAG07177.1 - 0.092 12.8 0.5 0.21 11.7 0.5 1.6 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Rnf-Nqr PF02508.14 OAG07178.1 - 0.011 15.8 0.9 0.016 15.2 0.9 1.1 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Mur_ligase_M PF08245.12 OAG07182.1 - 3.2e-06 27.3 0.0 7.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OAG07182.1 - 0.035 14.4 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Cupin_2 PF07883.11 OAG07183.1 - 1.3e-08 34.4 0.1 0.00014 21.5 0.0 2.7 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG07183.1 - 0.00067 19.3 0.1 0.18 11.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.22 OAG07183.1 - 0.028 14.1 0.4 0.44 10.1 0.0 2.6 2 1 0 2 2 2 0 Cupin BTB PF00651.31 OAG07184.1 - 0.017 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain tRNA_NucTransf2 PF09249.11 OAG07184.1 - 0.22 11.8 0.6 0.49 10.7 0.6 1.7 1 1 0 1 1 1 0 tRNA nucleotidyltransferase, second domain Sporozoite_P67 PF05642.11 OAG07184.1 - 0.25 9.4 0.7 0.29 9.2 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BTB PF00651.31 OAG07185.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain SAP PF02037.27 OAG07187.1 - 7.2e-05 22.4 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain SET PF00856.28 OAG07188.1 - 9.8e-16 58.6 0.0 2.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 SET domain TPR_8 PF13181.6 OAG07188.1 - 0.17 12.2 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Rhodanese PF00581.20 OAG07189.1 - 1.7e-06 28.5 0.0 2.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Dioxygenase_C PF00775.21 OAG07190.1 - 2.1e-07 30.5 0.1 3.9e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase DUF641 PF04859.12 OAG07190.1 - 0.099 13.0 0.7 0.17 12.2 0.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Y_phosphatase2 PF03162.13 OAG07191.1 - 6.7e-47 159.1 0.0 8.9e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAG07191.1 - 1.3e-10 41.6 0.0 4.2e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OAG07191.1 - 7.9e-06 25.7 0.2 1.2e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG07191.1 - 0.00083 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3984 PF13136.6 OAG07192.1 - 5.4e-52 177.2 22.5 8.4e-41 140.5 16.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3984) YL1 PF05764.13 OAG07192.1 - 0.00041 20.5 4.9 0.00077 19.6 4.9 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 OAG07192.1 - 0.27 10.9 10.0 0.55 9.9 10.0 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_transf_22 PF03901.17 OAG07193.1 - 1.4e-85 288.1 10.9 1.8e-85 287.7 10.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 OAG07194.1 - 5.8e-51 173.4 0.1 1.9e-35 122.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07194.1 - 4.3e-23 81.9 0.1 8e-22 77.8 0.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG07194.1 - 0.0022 16.8 3.3 0.051 12.3 3.3 2.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAG07194.1 - 0.0025 17.2 0.4 0.0089 15.4 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Spc29 PF17082.5 OAG07194.1 - 0.22 11.4 7.2 0.08 12.8 1.6 2.4 2 0 0 2 2 2 0 Spindle Pole Component 29 Fungal_trans_2 PF11951.8 OAG07195.1 - 3.4e-09 36.0 0.6 4.8e-09 35.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07195.1 - 8.4e-08 32.2 10.7 1.3e-07 31.6 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAG07196.1 - 2.4e-22 79.8 0.7 4.6e-22 79.0 0.1 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_92 PF07971.12 OAG07197.1 - 1.2e-145 486.0 0.0 1.5e-145 485.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG07197.1 - 1.1e-56 192.4 0.1 1.8e-56 191.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain 2OG-FeII_Oxy_3 PF13640.6 OAG07198.1 - 4.3e-08 33.9 0.0 6.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dabb PF07876.12 OAG07199.1 - 1.7e-10 41.4 0.0 2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dicty_REP PF05086.12 OAG07200.1 - 0.068 11.1 1.5 0.094 10.7 1.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.18 OAG07201.1 - 3.4e-07 30.3 10.1 8.2e-07 29.1 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helo_like_N PF17111.5 OAG07201.1 - 3.4e-06 26.6 13.8 8.5e-05 22.0 6.6 2.3 1 1 1 2 2 2 2 Fungal N-terminal domain of STAND proteins LMBR1 PF04791.16 OAG07201.1 - 0.24 10.3 3.9 0.38 9.6 3.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Porin_3 PF01459.22 OAG07203.1 - 5.1e-64 216.3 8.4 5.8e-64 216.2 8.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.31 OAG07204.1 - 1.3e-21 76.5 1.0 2.1e-21 75.8 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.24 OAG07205.1 - 9.9e-46 156.1 0.1 1.2e-45 155.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 OAG07205.1 - 0.0074 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Pectinesterase YL1 PF05764.13 OAG07205.1 - 0.059 13.5 5.3 0.1 12.7 5.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF3323 PF11796.8 OAG07205.1 - 0.08 12.8 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) TFIIF_alpha PF05793.12 OAG07205.1 - 0.13 10.9 8.4 0.17 10.4 8.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med3 PF11593.8 OAG07205.1 - 0.44 9.7 4.4 0.65 9.1 4.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mpp10 PF04006.12 OAG07206.1 - 1.2e-115 387.4 31.6 2.7e-115 386.2 31.6 1.5 1 1 0 1 1 1 1 Mpp10 protein ACOX PF01756.19 OAG07207.1 - 3.8e-45 153.7 0.0 7.1e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG07207.1 - 9.2e-25 87.6 0.2 2e-24 86.5 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG07207.1 - 4e-11 43.0 0.0 9.1e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG07207.1 - 0.00038 20.7 0.0 0.26 11.5 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain PP2C PF00481.21 OAG07208.1 - 1.2e-83 280.8 0.0 1.6e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C FMN_dh PF01070.18 OAG07210.1 - 1.5e-13 50.5 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase WD40 PF00400.32 OAG07211.1 - 6.7e-40 134.3 22.2 8.4e-11 42.3 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG07211.1 - 3.6e-13 49.6 0.9 0.0018 18.5 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG07211.1 - 9.7e-08 31.3 0.3 0.18 10.7 0.0 4.2 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG07211.1 - 1.4e-07 30.6 5.7 0.082 11.5 0.1 4.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 OAG07211.1 - 2.8e-05 23.2 0.1 2.8e-05 23.2 0.1 2.4 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 OAG07211.1 - 0.0018 17.4 2.4 2.2 7.3 0.1 3.4 1 1 2 4 4 4 2 Protein of unknown function (DUF1513) Hira PF07569.11 OAG07211.1 - 0.0057 16.4 0.3 5.5 6.7 0.1 3.2 1 1 1 2 2 2 1 TUP1-like enhancer of split HPS3_N PF14761.6 OAG07211.1 - 0.0093 15.5 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 Frtz PF11768.8 OAG07211.1 - 0.012 14.0 0.0 0.022 13.1 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 OAG07211.1 - 0.021 13.6 0.3 8.9 4.9 0.0 3.1 1 1 2 3 3 3 0 Nup133 N terminal like Coatomer_WDAD PF04053.14 OAG07211.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Sugar_tr PF00083.24 OAG07212.1 - 5.8e-91 305.6 12.0 9.7e-91 304.9 11.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07212.1 - 7.2e-22 77.8 30.4 7.2e-22 77.8 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG07212.1 - 3e-05 22.6 4.0 3e-05 22.6 4.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Wzz PF02706.15 OAG07212.1 - 2.1 8.7 5.0 36 4.8 0.0 3.5 3 0 0 3 3 3 0 Chain length determinant protein AIP3 PF03915.13 OAG07213.1 - 1e-151 505.7 13.6 1.5e-151 505.1 13.6 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 PKK PF12474.8 OAG07213.1 - 0.0043 17.2 7.9 0.0043 17.2 7.9 2.9 3 0 0 3 3 3 1 Polo kinase kinase LemA PF04011.12 OAG07213.1 - 2 8.2 7.0 0.12 12.2 0.2 2.5 2 0 0 2 2 2 0 LemA family RasGAP_C PF03836.15 OAG07213.1 - 5.3 7.2 9.7 8.6 6.5 1.6 3.9 4 1 0 4 4 4 0 RasGAP C-terminus Flavi_NS4B PF01349.17 OAG07216.1 - 0.23 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B Ecl1 PF12855.7 OAG07217.1 - 1.2e-17 65.7 17.3 1.3e-17 65.5 17.3 1.0 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins RR_TM4-6 PF06459.12 OAG07217.1 - 0.015 15.2 0.2 0.02 14.8 0.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PLATZ PF04640.14 OAG07217.1 - 0.067 13.8 0.6 0.16 12.6 0.6 1.7 1 0 0 1 1 1 0 PLATZ transcription factor Inositol_P PF00459.25 OAG07218.1 - 9.2e-37 127.0 0.8 6.2e-35 121.0 0.8 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family DUF5371 PF17341.2 OAG07218.1 - 0.08 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5371) Metallophos_2 PF12850.7 OAG07219.1 - 9.8e-11 42.1 0.0 1.4e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF5568 PF17724.1 OAG07220.1 - 0.00037 20.4 5.7 0.21 11.4 0.2 3.2 1 1 2 3 3 3 3 Family of unknown function (DUF5568) JSRP PF15312.6 OAG07220.1 - 0.006 16.5 3.6 33 4.5 0.1 4.2 1 1 1 3 3 3 0 Junctional sarcoplasmic reticulum protein ITAM PF02189.15 OAG07220.1 - 0.038 14.5 0.6 2.5e+02 2.4 0.0 4.6 5 0 0 5 5 5 0 Immunoreceptor tyrosine-based activation motif End_N_terminal PF12218.8 OAG07220.1 - 0.056 13.2 5.0 1.4e+02 2.3 0.0 4.9 5 0 0 5 5 5 0 N terminal extension of bacteriophage endosialidase PE_PPE_C PF12484.8 OAG07220.1 - 0.43 11.5 9.1 5.8 7.9 2.0 3.0 1 1 2 3 3 3 0 Polymorphic PE/PPE proteins C terminal DUF4716 PF15837.5 OAG07220.1 - 1.6 8.8 5.8 15 5.7 0.4 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4716) HET PF06985.11 OAG07221.1 - 1.6e-34 119.4 0.2 3.9e-34 118.1 0.1 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) PnpCD_PnpD_N PF18191.1 OAG07221.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal DUF1018 PF06252.12 OAG07222.1 - 0.077 14.0 0.3 0.42 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Aminotran_5 PF00266.19 OAG07224.1 - 2.8e-31 108.8 0.0 3.6e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Peptidase_M28 PF04389.17 OAG07225.1 - 7.1e-35 120.5 0.2 1e-34 120.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG07225.1 - 0.00057 19.6 0.1 0.001 18.8 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 OAG07225.1 - 0.0053 16.2 0.2 3.2 7.2 0.0 2.8 3 0 0 3 3 3 2 Nicastrin AAA_23 PF13476.6 OAG07225.1 - 0.058 13.9 1.3 0.27 11.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain Multi_ubiq PF14452.6 OAG07225.1 - 0.12 12.6 0.0 0.62 10.4 0.1 2.1 3 0 0 3 3 3 0 Multiubiquitin Peptidase_M20 PF01546.28 OAG07226.1 - 5.6e-23 81.7 0.2 9.3e-23 81.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG07226.1 - 2.4e-14 53.1 0.1 5.6e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DASH_Dad2 PF08654.10 OAG07229.1 - 0.058 13.8 0.1 0.091 13.2 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 IKI3 PF04762.12 OAG07230.1 - 2.6e-299 995.4 0.0 3.6e-299 995.0 0.0 1.1 1 0 0 1 1 1 1 IKI3 family COX7C PF02935.16 OAG07230.1 - 1.4e-18 66.9 0.7 1.4e-18 66.9 0.7 2.0 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VIIc Gmad1 PF10647.9 OAG07230.1 - 7.2e-05 22.7 1.6 1.1 8.9 0.0 3.5 3 1 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain ANAPC4_WD40 PF12894.7 OAG07230.1 - 0.00073 19.8 0.1 1.1 9.6 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OAG07230.1 - 0.021 13.9 0.1 4.6 6.2 0.0 2.6 3 0 0 3 3 3 0 Coatomer WD associated region Se-cys_synth_N PF12390.8 OAG07230.1 - 0.033 14.4 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Phage_Nu1 PF07471.12 OAG07230.1 - 0.2 11.4 0.9 0.55 10.0 0.9 1.7 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 rRNA_proc-arch PF13234.6 OAG07231.1 - 1.4e-88 297.3 0.4 3.1e-88 296.2 0.4 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 OAG07231.1 - 1.8e-56 190.4 2.8 6.9e-56 188.4 1.3 2.4 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 OAG07231.1 - 2.5e-19 69.7 0.5 8.4e-19 68.0 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG07231.1 - 4.5e-07 30.2 0.0 2.7e-06 27.7 0.0 2.2 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG07231.1 - 7.3e-06 26.1 0.0 3.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5388 PF17363.2 OAG07231.1 - 0.011 15.9 0.1 0.056 13.6 0.1 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5388) Plk4_PB2 PF18409.1 OAG07231.1 - 0.026 15.2 0.7 16 6.3 0.1 3.2 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 ATPase_2 PF01637.18 OAG07231.1 - 0.045 13.7 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 OAG07231.1 - 0.048 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgoMid PF16487.5 OAG07231.1 - 0.057 13.7 1.5 11 6.3 0.2 3.0 2 0 0 2 2 2 0 Mid domain of argonaute E2_bind PF08825.10 OAG07231.1 - 0.1 12.8 0.6 0.43 10.8 0.3 2.2 1 1 1 2 2 2 0 E2 binding domain AAA_22 PF13401.6 OAG07231.1 - 0.12 12.6 0.0 0.63 10.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain KELK PF15796.5 OAG07231.1 - 0.13 12.7 3.3 0.14 12.7 1.0 2.3 2 0 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_leu_zip PF10473.9 OAG07231.1 - 0.14 12.1 7.2 0.11 12.6 1.3 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MLD PF11647.8 OAG07231.1 - 0.16 12.2 0.4 0.49 10.7 0.4 1.8 1 0 0 1 1 1 0 Membrane Localization Domain ATPase PF06745.13 OAG07231.1 - 0.32 10.3 1.7 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 KaiC APG6_N PF17675.1 OAG07231.1 - 1 9.9 5.5 8.2 7.0 1.4 3.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Cut8 PF08559.10 OAG07233.1 - 1.7e-80 270.1 0.0 2.2e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Acyl_transf_1 PF00698.21 OAG07234.1 - 5.7e-18 65.5 0.0 2.9e-12 46.7 0.0 2.1 1 1 1 2 2 2 2 Acyl transferase domain adh_short_C2 PF13561.6 OAG07235.1 - 2.1e-42 145.3 0.4 2.5e-42 145.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG07235.1 - 2.1e-37 128.5 0.1 2.6e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG07235.1 - 1.1e-14 54.7 0.1 5.2e-14 52.6 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG07235.1 - 0.0054 16.2 0.0 0.014 14.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG07235.1 - 0.025 13.6 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Prenyltransf PF01255.19 OAG07235.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Med5 PF08689.10 OAG07236.1 - 5.1e-149 498.1 0.0 3.5e-148 495.4 0.0 2.1 1 1 0 1 1 1 1 Mediator complex subunit Med5 Aldo_ket_red PF00248.21 OAG07238.1 - 9.4e-34 116.9 0.0 2.3e-31 109.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ELFV_dehydrog PF00208.21 OAG07239.1 - 3.5e-86 288.9 3.4 4.3e-86 288.6 3.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OAG07239.1 - 4.7e-51 172.1 0.0 8.6e-51 171.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DASH_Ask1 PF08655.10 OAG07240.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Ask1 FA_desaturase PF00487.24 OAG07241.1 - 3.4e-27 95.9 12.3 4.9e-27 95.4 12.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 OAG07241.1 - 6.7e-18 63.9 0.9 1.2e-17 63.1 0.9 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Ank_3 PF13606.6 OAG07242.1 - 0.00056 20.2 0.0 0.0008 19.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 OAG07242.1 - 0.003 18.1 0.0 0.0038 17.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG07242.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeat Anp1 PF03452.14 OAG07243.1 - 9.3e-97 323.6 0.0 1.1e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 MobB PF03205.14 OAG07243.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ecm33 PF12454.8 OAG07245.1 - 4.6e-10 39.5 0.9 1.2e-09 38.1 0.9 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 OAG07245.1 - 5.9e-07 29.6 5.1 0.082 13.0 0.1 4.2 1 1 3 4 4 4 4 Receptor L domain LRR_4 PF12799.7 OAG07245.1 - 2.3 8.8 18.2 4 8.0 0.4 5.4 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) HhH-GPD PF00730.25 OAG07248.1 - 8.5e-13 48.7 0.0 1.4e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UCR_14kD PF02271.16 OAG07249.1 - 1.4e-44 150.2 0.1 1.7e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 OAG07250.1 - 7.4e-65 214.9 2.9 1.6e-23 82.5 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein SUR7 PF06687.12 OAG07252.1 - 2.8e-40 138.2 22.1 3.4e-40 138.0 22.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2721 PF11026.8 OAG07252.1 - 0.012 15.5 14.9 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Phtf-FEM1B_bdg PF12129.8 OAG07252.1 - 9.7 6.0 7.8 0.85 9.4 3.1 1.6 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Sulf_transp PF04143.14 OAG07253.1 - 1e-32 114.0 30.1 1.9e-32 113.1 30.1 1.5 1 1 0 1 1 1 1 Sulphur transport LapA_dom PF06305.11 OAG07253.1 - 2.7 7.9 0.0 2.7 7.9 0.0 3.8 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Fungal_trans PF04082.18 OAG07254.1 - 8.1e-10 38.2 0.0 1.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07254.1 - 9.7e-10 38.4 5.8 1.9e-09 37.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 OAG07254.1 - 0.024 14.2 0.1 0.062 12.9 0.1 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like Lactamase_B PF00753.27 OAG07255.1 - 2e-18 67.1 1.2 3.8e-18 66.2 1.2 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG07255.1 - 0.0019 17.7 0.1 0.0031 17.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG07255.1 - 0.06 13.2 0.1 0.098 12.5 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 OAG07256.1 - 9.6e-09 34.9 0.0 4.2e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG07256.1 - 0.071 13.1 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG07256.1 - 0.12 11.3 0.0 28 3.6 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein DUF1275 PF06912.11 OAG07257.1 - 4.6e-42 144.1 15.4 6.1e-42 143.7 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Lyase_1 PF00206.20 OAG07258.1 - 2.4e-23 83.0 0.0 3.7e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAG07258.1 - 1.2e-18 67.4 0.0 4.2e-18 65.7 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus TPMT PF05724.11 OAG07258.1 - 0.057 13.1 0.2 0.66 9.6 0.2 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) RNA_pol_Rbc25 PF08292.12 OAG07258.1 - 0.081 13.2 0.4 0.18 12.0 0.4 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 BLUF PF04940.12 OAG07258.1 - 0.09 12.9 0.1 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Sensors of blue-light using FAD DUF1631 PF07793.11 OAG07261.1 - 5.9 5.2 9.1 8.2 4.7 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) HATPase_c_3 PF13589.6 OAG07262.1 - 7.5e-15 55.0 0.0 1.8e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 OAG07262.1 - 1e-06 28.6 0.1 1.6e-05 24.7 0.0 2.5 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 OAG07262.1 - 0.0037 17.7 0.0 0.0097 16.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Polysacc_deac_1 PF01522.21 OAG07263.1 - 7e-26 90.6 0.0 1.9e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase HTH_39 PF14090.6 OAG07263.1 - 0.011 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Ribonuc_2-5A PF06479.12 OAG07263.1 - 0.026 14.7 0.1 6.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A Methyltransf_23 PF13489.6 OAG07263.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 OAG07263.1 - 0.15 13.1 0.0 0.37 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain YCII PF03795.14 OAG07264.1 - 0.00024 21.5 0.0 0.00033 21.0 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Ribonuc_red_lgC PF02867.15 OAG07265.1 - 2.2e-189 630.4 0.0 2.9e-189 630.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OAG07265.1 - 2.1e-24 85.3 0.0 4.9e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OAG07265.1 - 9e-17 61.4 0.0 2.2e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Ribosomal_L17 PF01196.19 OAG07266.1 - 9.5e-32 109.8 0.1 9.5e-32 109.8 0.1 2.2 3 0 0 3 3 3 1 Ribosomal protein L17 Germane PF10646.9 OAG07266.1 - 0.089 13.6 0.5 0.66 10.8 0.1 2.3 2 1 1 3 3 3 0 Sporulation and spore germination Methyltransf_16 PF10294.9 OAG07267.1 - 2.7e-47 160.7 0.0 3.3e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DUF43 PF01861.16 OAG07267.1 - 6.6e-06 25.5 0.0 8.7e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain MTS PF05175.14 OAG07267.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Torus PF16131.5 OAG07268.1 - 0.082 13.6 0.6 0.082 13.6 0.6 5.1 5 1 0 6 6 6 0 Torus domain 2OG-FeII_Oxy_3 PF13640.6 OAG07269.1 - 1.1e-08 35.8 0.0 1.8e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OAG07269.1 - 0.01 16.3 0.1 0.036 14.5 0.1 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.6 OAG07270.1 - 6.7e-16 58.7 0.0 1.3e-15 57.8 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 OAG07270.1 - 6.5e-07 29.3 0.0 0.0004 20.3 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin COesterase PF00135.28 OAG07271.1 - 6.6e-64 216.6 0.0 6.8e-57 193.5 0.0 2.1 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG07271.1 - 4.2e-08 33.3 0.2 9.8e-08 32.1 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_2 PF00891.18 OAG07272.1 - 4.8e-16 58.7 0.0 5.9e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 OAG07272.1 - 0.00019 21.3 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.22 OAG07273.1 - 3.6e-74 250.2 0.0 4.9e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OAG07273.1 - 7.8e-26 91.0 0.0 1.2e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG07273.1 - 2.9e-24 85.9 0.0 5.1e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG07273.1 - 2.4e-11 44.3 0.0 9.2e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAG07273.1 - 0.00031 21.0 0.0 0.00069 19.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.11 OAG07273.1 - 0.073 13.2 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 NrdI Flavodoxin like Alba PF01918.21 OAG07274.1 - 0.00016 21.4 0.1 0.00032 20.5 0.1 1.6 1 0 0 1 1 1 1 Alba Acetyltransf_1 PF00583.25 OAG07275.1 - 8.7e-12 45.3 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG07275.1 - 4.5e-08 33.1 0.1 6.5e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG07275.1 - 8.7e-08 32.0 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG07275.1 - 5.3e-05 23.6 0.0 8.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG07275.1 - 0.0048 17.0 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FSA_C PF10479.9 OAG07276.1 - 1.8 6.6 5.2 2.3 6.2 5.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CTP_transf_like PF01467.26 OAG07277.1 - 1.1e-19 71.0 0.0 8.4e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF1996 PF09362.10 OAG07278.1 - 8.7e-66 222.3 4.2 8.7e-66 222.3 4.2 1.9 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) UPF0160 PF03690.13 OAG07279.1 - 2.9e-124 414.9 0.0 3.2e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 OAG07280.1 - 2.2e-153 511.2 8.4 2.5e-153 511.0 8.4 1.0 1 0 0 1 1 1 1 ICE2 HET PF06985.11 OAG07281.1 - 4.2e-12 46.6 8.4 9.4e-11 42.3 2.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) IMS PF00817.20 OAG07281.1 - 0.054 13.5 0.0 0.067 13.2 0.0 1.3 1 1 0 1 1 1 0 impB/mucB/samB family AAA PF00004.29 OAG07282.1 - 1.5e-20 73.9 0.0 3.3e-19 69.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG07282.1 - 0.00054 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG07282.1 - 0.001 19.5 0.1 0.0048 17.3 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OAG07282.1 - 0.0011 19.6 0.2 0.005 17.4 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG07282.1 - 0.0033 17.4 0.0 0.0086 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG07282.1 - 0.006 16.9 0.5 0.062 13.6 0.3 2.7 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG07282.1 - 0.019 15.4 0.1 0.077 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAG07282.1 - 0.022 14.9 0.0 0.068 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 OAG07282.1 - 0.03 13.7 0.5 1.3 8.3 0.2 2.3 1 1 0 2 2 2 0 KaiC Zot PF05707.12 OAG07282.1 - 0.033 13.8 0.1 0.39 10.3 0.1 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) TIP49 PF06068.13 OAG07282.1 - 0.081 12.1 0.1 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 OAG07282.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 OAG07282.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Spore_GerQ PF09671.10 OAG07282.1 - 0.15 12.1 0.0 0.95 9.5 0.0 2.3 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) zf-C2H2 PF00096.26 OAG07285.1 - 9.2e-10 38.4 11.4 0.0075 16.7 0.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG07285.1 - 2.8e-07 30.8 7.3 0.079 13.8 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 OAG07285.1 - 0.015 15.5 4.4 0.29 11.5 0.8 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 OAG07285.1 - 0.15 12.7 0.9 1.9 9.2 0.1 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-BED PF02892.15 OAG07285.1 - 0.16 12.0 0.6 0.41 10.7 0.6 1.7 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.6 OAG07285.1 - 0.46 10.5 4.2 26 5.0 2.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG07285.1 - 1.1 9.8 5.4 15 6.2 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.16 OAG07286.1 - 9.9e-22 77.3 60.2 8.7e-21 74.2 49.6 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG07286.1 - 1.1e-05 24.9 23.6 1.6e-05 24.4 23.6 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB UCR_Fe-S_N PF10399.9 OAG07286.1 - 2.9 7.3 6.1 1 8.8 1.0 2.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Methyltransf_11 PF08241.12 OAG07287.1 - 5.6e-13 49.4 0.0 9.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG07287.1 - 3.5e-11 43.7 0.0 6.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG07287.1 - 1.2e-08 34.5 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAG07287.1 - 2.3e-08 34.0 0.0 3.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG07287.1 - 3e-07 30.4 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG07287.1 - 2.7e-06 28.0 0.0 4.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG07287.1 - 0.00031 20.3 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OAG07287.1 - 0.00048 19.6 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 OAG07287.1 - 0.00051 20.0 0.0 0.00077 19.4 0.0 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase AdoMet_MTase PF07757.13 OAG07287.1 - 0.00097 19.5 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 OAG07287.1 - 0.0088 16.0 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG07287.1 - 0.033 14.0 0.0 0.044 13.5 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 OAG07287.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_114 PF03537.13 OAG07288.1 - 2.7e-44 151.2 0.4 3e-44 151.1 0.4 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Steroid_dh PF02544.16 OAG07289.1 - 2.6e-17 63.2 0.1 4.6e-16 59.2 0.1 2.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAG07289.1 - 0.0035 16.9 0.8 0.0084 15.6 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Ribosomal_S13_N PF08069.12 OAG07290.1 - 0.018 15.1 0.3 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain SKG6 PF08693.10 OAG07291.1 - 2.6e-08 33.1 4.4 5.9e-08 32.0 4.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 OAG07291.1 - 2e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.6 OAG07291.1 - 0.00014 21.8 0.1 0.00056 19.8 0.0 1.9 1 1 1 2 2 2 1 TMEM154 protein family PAP_PilO PF06864.12 OAG07291.1 - 0.0025 16.7 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Pilin accessory protein (PilO) CcmD PF04995.14 OAG07291.1 - 0.0062 16.6 0.6 0.01 15.9 0.6 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF4448 PF14610.6 OAG07291.1 - 0.0096 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) BatD PF13584.6 OAG07291.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance MLANA PF14991.6 OAG07291.1 - 0.026 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A SIT PF15330.6 OAG07291.1 - 0.095 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4381 PF14316.6 OAG07291.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3301 PF11743.8 OAG07291.1 - 0.19 11.5 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Miga PF10265.9 OAG07291.1 - 0.23 10.4 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Mitoguardin Alpha_GJ PF03229.13 OAG07291.1 - 1.4 9.5 9.9 1.1 9.8 0.2 2.7 2 1 1 3 3 3 0 Alphavirus glycoprotein J Patatin PF01734.22 OAG07293.1 - 2e-16 60.8 1.4 4.6e-16 59.6 0.5 2.1 2 1 0 2 2 2 1 Patatin-like phospholipase ABC_tran PF00005.27 OAG07293.1 - 0.0004 20.9 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OAG07293.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 OAG07293.1 - 0.0044 16.3 0.0 0.0095 15.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 OAG07293.1 - 0.0045 17.3 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OAG07293.1 - 0.0093 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-RING_UBOX PF13445.6 OAG07293.1 - 0.03 14.3 8.3 0.11 12.5 8.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger AAA_16 PF13191.6 OAG07293.1 - 0.057 13.8 0.0 0.34 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OAG07293.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UIM PF02809.20 OAG07293.1 - 0.25 11.4 6.1 0.15 12.1 1.4 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-C3HC4 PF00097.25 OAG07293.1 - 4.4 7.3 18.4 0.019 14.8 7.0 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA_18 PF13238.6 OAG07294.1 - 0.00029 21.4 0.0 0.001 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OAG07294.1 - 0.00083 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain PRK PF00485.18 OAG07294.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 OAG07294.1 - 0.0024 18.3 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG07294.1 - 0.0031 17.8 0.0 0.0059 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAG07294.1 - 0.0044 17.4 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAG07294.1 - 0.0044 16.3 0.1 0.026 13.8 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 OAG07294.1 - 0.0049 16.0 0.0 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein RuvB_N PF05496.12 OAG07294.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAG07294.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OAG07294.1 - 0.016 15.3 0.2 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG07294.1 - 0.022 15.2 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG07294.1 - 0.074 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.17 OAG07294.1 - 0.075 12.7 0.0 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase dNK PF01712.19 OAG07294.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase NTPase_1 PF03266.15 OAG07294.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NTPase Torsin PF06309.11 OAG07294.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.6 OAG07294.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG07294.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 OAG07294.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 OAG07294.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 OAG07294.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 OAG07294.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 OAG07295.1 - 1.8e-14 54.3 0.0 7e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG07295.1 - 0.01 15.9 0.0 0.23 11.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG07295.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DAO PF01266.24 OAG07296.1 - 1.8e-53 182.4 0.1 9.9e-53 179.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAG07296.1 - 4.9e-44 149.2 0.2 9.9e-44 148.2 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 OAG07296.1 - 3.5e-09 36.3 0.1 9.7e-09 34.8 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG07296.1 - 1.9e-06 27.5 0.0 6.9e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG07296.1 - 0.00014 21.2 0.3 0.0004 19.7 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG07296.1 - 0.0054 15.9 0.1 0.026 13.6 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 OAG07296.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG07296.1 - 0.018 13.8 0.1 0.032 13.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 OAG07296.1 - 0.026 14.7 2.7 0.034 14.4 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG07296.1 - 0.067 13.8 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG07296.1 - 0.11 11.8 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG07296.1 - 0.16 11.2 0.1 1.6 7.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain VTC PF09359.10 OAG07297.1 - 4.6e-09 36.1 0.0 1.3e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 VTC domain SPX PF03105.19 OAG07297.1 - 1.7e-06 28.2 0.8 0.0002 21.4 0.0 4.6 2 2 1 4 4 4 3 SPX domain ORC6 PF05460.13 OAG07297.1 - 0.088 12.1 2.9 0.15 11.3 2.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ALS_ss_C PF10369.9 OAG07298.1 - 6.3e-15 55.1 0.0 9.5e-14 51.4 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 OAG07298.1 - 3.5e-13 49.1 0.1 6.8e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 OAG07298.1 - 3.9e-08 33.0 0.0 6.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.8 OAG07298.1 - 0.11 12.6 0.2 0.37 10.9 0.0 2.0 3 0 0 3 3 3 0 Limkain b1 KH_1 PF00013.29 OAG07299.1 - 1.4e-12 47.3 0.3 1.6e-09 37.5 0.2 2.7 2 0 0 2 2 2 2 KH domain Aconitase PF00330.20 OAG07300.1 - 7.3e-142 473.6 0.0 9.1e-142 473.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG07300.1 - 6.6e-41 139.7 0.0 1.1e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosom_S30AE_C PF16321.5 OAG07300.1 - 0.33 10.7 2.1 28 4.5 0.2 3.2 4 0 0 4 4 4 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Hamartin PF04388.12 OAG07302.1 - 0.35 9.5 2.1 0.38 9.4 2.1 1.0 1 0 0 1 1 1 0 Hamartin protein DSBA PF01323.20 OAG07303.1 - 5e-26 91.7 0.0 5.6e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF4143 PF13635.6 OAG07303.1 - 0.03 14.5 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) Beta_helix PF13229.6 OAG07305.1 - 0.0002 21.2 19.8 0.077 12.8 0.4 2.3 1 1 1 2 2 2 2 Right handed beta helix region SOG2 PF10428.9 OAG07306.1 - 3.3e-23 82.7 11.7 2.4e-13 50.1 0.8 4.0 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 OAG07306.1 - 4.1e-20 71.3 5.9 3.2e-09 36.4 0.5 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAG07306.1 - 6.3e-11 42.3 2.0 0.00069 20.0 0.0 3.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAG07306.1 - 0.015 15.8 0.7 83 4.4 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 OAG07306.1 - 0.14 12.3 2.9 23 5.4 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat DUF5082 PF16888.5 OAG07306.1 - 0.17 12.2 0.3 8.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) RGS PF00615.19 OAG07309.1 - 5.8e-12 45.9 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF647 PF04884.14 OAG07310.1 - 5.7e-116 386.3 1.7 7.1e-116 386.0 1.7 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis HET PF06985.11 OAG07311.1 - 7.5e-24 84.7 0.0 1.3e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIG-Y PF15159.6 OAG07312.1 - 0.063 14.2 1.2 0.17 12.8 1.2 1.7 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF2070 PF09843.9 OAG07312.1 - 0.15 10.3 0.1 0.26 9.5 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sugar_tr PF00083.24 OAG07314.1 - 2.4e-108 362.9 25.4 4e-108 362.2 25.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07314.1 - 3.3e-22 78.9 55.8 6.1e-16 58.3 23.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily UTP25 PF06862.12 OAG07315.1 - 1.7e-187 623.9 0.7 2.1e-187 623.7 0.7 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 JAB PF01398.21 OAG07316.1 - 2.5e-21 75.9 0.0 4.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAG07316.1 - 6.2e-21 74.9 1.2 1.1e-20 74.1 1.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 OAG07316.1 - 1e-05 25.7 0.0 6.9e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) TFIID-18kDa PF02269.16 OAG07317.1 - 4.3e-25 87.6 0.1 8.2e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 OAG07317.1 - 5.8e-05 23.4 0.2 0.00014 22.2 0.2 1.6 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAG07317.1 - 0.0015 18.6 0.1 0.0026 17.9 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 OAG07317.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG07317.1 - 0.042 13.9 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 OAG07317.1 - 0.072 13.5 0.7 0.072 13.5 0.7 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF1242 PF06842.12 OAG07318.1 - 3.2e-16 58.8 0.5 4.5e-16 58.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Antimicrobial_6 PF08036.11 OAG07320.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide NUP50 PF08911.11 OAG07320.1 - 6.8 7.4 8.3 0.28 11.9 1.3 2.4 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Protoglobin PF11563.8 OAG07321.1 - 1.5e-60 203.7 0.2 1.8e-60 203.4 0.2 1.1 1 0 0 1 1 1 1 Protoglobin Lipocalin_5 PF13924.6 OAG07323.1 - 9.4e-30 103.3 0.0 1.1e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Cellulase PF00150.18 OAG07324.1 - 1.2e-50 172.6 10.3 1.5e-50 172.2 10.3 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-RING_5 PF14634.6 OAG07325.1 - 0.00014 21.7 4.6 0.00034 20.5 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain CENP-Q PF13094.6 OAG07325.1 - 0.026 14.7 5.2 0.05 13.8 5.2 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TEX13 PF15186.6 OAG07325.1 - 0.3 10.8 2.7 0.58 9.8 2.7 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family FUSC PF04632.12 OAG07325.1 - 3.3 6.1 3.8 4.5 5.7 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family COesterase PF00135.28 OAG07327.1 - 4.8e-77 260.0 0.0 1.3e-69 235.5 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG07327.1 - 0.00075 19.4 0.1 0.0016 18.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF898 PF05987.13 OAG07328.1 - 0.001 18.2 0.7 0.001 18.2 0.7 2.6 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF4079 PF13301.6 OAG07328.1 - 3.3 7.9 11.9 18 5.5 11.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) AMP-binding PF00501.28 OAG07329.1 - 4.1e-68 229.9 0.0 5.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG07329.1 - 1.8e-11 44.8 0.1 3.3e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain COesterase PF00135.28 OAG07330.1 - 2.6e-86 290.5 0.0 3.2e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG07330.1 - 0.0016 18.4 0.0 0.008 16.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG07330.1 - 0.0061 16.1 0.3 0.01 15.3 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family NmrA PF05368.13 OAG07331.1 - 2.4e-13 50.2 0.0 3.2e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG07331.1 - 5.6e-12 45.9 0.0 9.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG07331.1 - 0.0078 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG07331.1 - 0.048 13.1 0.0 0.26 10.7 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RHS_repeat PF05593.14 OAG07334.1 - 0.013 16.0 0.2 0.13 12.8 0.0 2.6 1 1 1 2 2 2 0 RHS Repeat SVIP PF15811.5 OAG07334.1 - 0.34 11.4 5.4 0.51 10.8 5.4 1.3 1 0 0 1 1 1 0 Small VCP/p97-interacting protein p450 PF00067.22 OAG07335.1 - 4.8e-65 220.1 0.0 6.2e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 OAG07336.1 - 1.5e-10 40.7 0.6 0.00044 20.0 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTP_transf_like PF01467.26 OAG07339.1 - 0.12 12.6 0.0 1.2 9.3 0.0 2.3 1 1 0 1 1 1 0 Cytidylyltransferase-like DLH PF01738.18 OAG07340.1 - 4.4e-22 78.7 0.0 5.8e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OAG07340.1 - 0.038 14.6 0.0 0.069 13.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG07340.1 - 0.042 13.5 0.0 5.9 6.4 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold AMP-binding PF00501.28 OAG07342.1 - 7.3e-65 219.2 0.1 9e-65 218.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG07342.1 - 1.4e-11 45.2 0.1 4.5e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NMO PF03060.15 OAG07342.1 - 0.027 13.8 0.2 0.045 13.1 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Ketoacyl-synt_2 PF13723.6 OAG07342.1 - 0.039 13.6 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Transferase PF02458.15 OAG07343.1 - 5.6e-30 104.3 0.0 1.2e-18 67.0 0.0 3.1 2 1 0 2 2 2 2 Transferase family ACOX PF01756.19 OAG07344.1 - 2.8e-40 137.8 1.0 5.4e-40 136.9 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG07344.1 - 4.4e-22 79.0 0.7 1.1e-21 77.6 0.7 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG07344.1 - 6.2e-08 32.7 0.0 1.2e-06 28.6 0.0 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG07344.1 - 0.043 14.0 0.1 0.51 10.5 0.1 2.3 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AT_hook PF02178.19 OAG07345.1 - 0.031 14.1 0.6 0.095 12.6 0.6 1.9 1 0 0 1 1 1 0 AT hook motif eIF3_subunit PF08597.10 OAG07345.1 - 9.2 6.1 17.0 0.74 9.7 4.6 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Pec_lyase_C PF00544.19 OAG07347.1 - 1.2e-39 136.1 2.2 1.5e-39 135.8 2.2 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG07347.1 - 4.6e-05 23.3 11.7 0.001 19.0 11.7 2.2 1 1 0 1 1 1 1 Right handed beta helix region Fungal_trans PF04082.18 OAG07348.1 - 4.6e-15 55.4 0.6 8.1e-15 54.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07348.1 - 5.4e-08 32.8 8.7 8.3e-08 32.2 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG07349.1 - 4.3e-14 52.2 2.7 6.9e-14 51.5 2.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Saf_2TM PF18303.1 OAG07350.1 - 7.3 6.2 5.8 3.7 7.1 1.3 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF1360 PF07098.11 OAG07351.1 - 0.054 13.4 0.8 0.47 10.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1360) DUF4423 PF14394.6 OAG07351.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF3325 PF11804.8 OAG07353.1 - 0.036 14.2 5.3 3 8.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Phospholamban PF04272.14 OAG07355.1 - 2.9 7.4 4.7 2.3 7.7 2.2 2.1 2 0 0 2 2 2 0 Phospholamban RTA1 PF04479.13 OAG07355.1 - 3.1 7.3 11.9 0.22 11.1 6.1 1.9 2 1 0 2 2 2 0 RTA1 like protein HET PF06985.11 OAG07356.1 - 9.1e-34 116.9 0.0 1.3e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Troponin-I_N PF11636.8 OAG07358.1 - 0.0026 17.7 1.7 0.0026 17.7 1.7 2.5 2 0 0 2 2 2 1 Troponin I residues 1-32 DUF4407 PF14362.6 OAG07358.1 - 0.055 12.8 4.5 0.062 12.6 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ISG65-75 PF11727.8 OAG07358.1 - 0.25 10.5 7.1 0.3 10.3 7.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Aa_trans PF01490.18 OAG07359.1 - 5.9e-78 262.4 24.4 7.1e-78 262.1 24.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tannase PF07519.11 OAG07360.1 - 1.1e-90 304.8 0.0 1.3e-90 304.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.7 OAG07361.1 - 2.5e-07 31.6 2.6 3.4e-07 31.1 2.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAG07361.1 - 0.00052 19.6 0.0 0.0031 17.1 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG07361.1 - 0.0078 15.7 0.0 0.084 12.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAG07361.1 - 0.047 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OAG07361.1 - 0.073 12.3 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 End_beta_propel PF12217.8 OAG07361.1 - 0.21 10.2 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase MFS_1 PF07690.16 OAG07362.1 - 5.5e-32 111.1 33.4 1e-20 74.0 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG07362.1 - 0.00085 18.3 5.2 0.0011 17.9 3.0 2.1 2 1 0 2 2 2 1 MFS_1 like family CHD5 PF04420.14 OAG07363.1 - 2.8e-55 186.5 1.0 3.4e-55 186.3 1.0 1.1 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.22 OAG07364.1 - 0.023 14.4 6.8 0.024 14.3 0.2 3.3 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat PPR_2 PF13041.6 OAG07365.1 - 3.3e-14 52.8 0.5 5.8e-05 23.2 0.0 4.8 5 2 2 7 7 7 5 PPR repeat family PPR PF01535.20 OAG07365.1 - 1.4e-12 47.0 0.3 0.0022 18.1 0.0 5.7 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 OAG07365.1 - 8.7e-09 35.3 0.6 0.013 15.6 0.1 4.3 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAG07365.1 - 0.0022 17.6 0.4 12 5.7 0.0 3.9 4 0 0 4 4 4 1 PPR repeat MRP-S25 PF13741.6 OAG07366.1 - 3.7e-66 223.0 0.7 4.1e-59 199.9 0.3 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 OAG07366.1 - 0.022 15.0 0.7 0.12 12.7 0.7 2.1 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 DUF3433 PF11915.8 OAG07368.1 - 6.9e-28 97.0 25.0 1.1e-17 64.2 4.2 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF3433) SLC3A2_N PF16028.5 OAG07368.1 - 0.074 12.6 3.2 0.14 11.7 0.3 3.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF997 PF06196.12 OAG07368.1 - 0.32 11.0 6.7 4.2 7.5 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF997) DUF3328 PF11807.8 OAG07369.1 - 3.2e-15 56.5 3.5 3.2e-15 56.5 3.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Toxin_7 PF05980.12 OAG07370.1 - 0.009 16.2 0.4 0.015 15.6 0.4 1.4 1 0 0 1 1 1 1 Toxin 7 DNA_ligase_C PF17879.1 OAG07371.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 DNA ligase C-terminal domain DUF5597 PF18120.1 OAG07373.1 - 3.9e-26 91.7 0.0 7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 OAG07373.1 - 1.2e-11 44.6 1.0 1.4e-11 44.4 0.1 1.5 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 OAG07373.1 - 1.1e-09 38.4 0.0 2.9e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 OAG07373.1 - 0.12 11.6 0.4 0.21 10.7 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 Val_tRNA-synt_C PF10458.9 OAG07373.1 - 0.19 12.0 0.1 0.44 10.9 0.1 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Zn_clus PF00172.18 OAG07374.1 - 9.5e-07 28.8 7.9 1.7e-06 28.1 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAG07375.1 - 2.7e-75 254.0 18.9 2.7e-75 254.0 18.9 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07375.1 - 1.7e-21 76.5 32.7 8.4e-16 57.8 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5048 PF16467.5 OAG07376.1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5048) DUF3810 PF12725.7 OAG07376.1 - 0.049 13.0 0.4 0.086 12.2 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Lipase_GDSL_2 PF13472.6 OAG07377.1 - 1.3e-10 42.0 0.1 2.1e-10 41.3 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TRI12 PF06609.13 OAG07378.1 - 1.5e-57 195.4 17.7 1.9e-57 195.0 17.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG07378.1 - 5.6e-24 84.7 32.1 5.6e-24 84.7 32.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Tymo_coat PF00983.18 OAG07378.1 - 0.05 13.4 0.2 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Tymovirus coat protein DUF872 PF05915.12 OAG07378.1 - 3.5 7.8 6.5 6.2 7.0 3.1 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) MIP PF00230.20 OAG07380.1 - 2.5e-43 148.4 16.2 3.3e-43 148.0 16.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein p450 PF00067.22 OAG07382.1 - 5.9e-58 196.7 0.0 7.6e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2025 PF09634.10 OAG07382.1 - 0.0073 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2025) Epimerase PF01370.21 OAG07383.1 - 5.4e-11 42.4 0.0 1.2e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG07383.1 - 2.4e-07 30.5 0.2 6.7e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG07383.1 - 5.2e-06 25.8 0.0 1.6e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG07383.1 - 2.3e-05 24.4 0.0 0.0001 22.3 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 OAG07383.1 - 0.00016 21.2 0.2 0.018 14.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 OAG07383.1 - 0.0028 17.2 0.1 0.0076 15.8 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 OAG07383.1 - 0.0029 16.7 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.32 OAG07383.1 - 0.032 15.1 0.1 0.1 13.5 0.1 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Glyco_transf_90 PF05686.12 OAG07384.1 - 1.8e-08 33.7 0.1 6.9e-07 28.5 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 Rtt106 PF08512.12 OAG07385.1 - 4.3e-29 100.8 0.0 6.8e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Trp_oprn_chp PF09534.10 OAG07386.1 - 0.022 14.5 2.1 0.29 10.9 0.3 2.7 1 1 2 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pyr_redox_2 PF07992.14 OAG07389.1 - 1.6e-14 53.9 0.0 2.1e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG07389.1 - 0.0001 21.6 0.0 0.017 14.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG07389.1 - 0.00012 21.3 0.2 0.00038 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG07389.1 - 0.0002 20.2 0.1 0.00041 19.2 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG07389.1 - 0.001 18.4 0.0 0.022 14.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG07389.1 - 0.0013 18.9 0.2 0.003 17.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG07389.1 - 0.0015 18.6 0.2 0.41 10.6 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG07389.1 - 0.0025 17.0 0.2 0.01 15.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG07389.1 - 0.0046 16.6 1.2 0.31 10.6 0.7 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG07389.1 - 0.0078 15.3 0.3 0.02 14.0 0.2 1.6 1 1 1 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 OAG07389.1 - 0.03 13.7 0.6 0.044 13.1 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG07389.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain UDPGT PF00201.18 OAG07390.1 - 0.085 11.6 0.2 0.29 9.9 0.1 1.8 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Gly_acyl_tr_C PF08444.10 OAG07391.1 - 0.14 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region UPF0542 PF15086.6 OAG07391.1 - 0.52 10.3 2.6 1.5 8.8 1.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 FMN_dh PF01070.18 OAG07394.1 - 0.041 12.9 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF4525 PF15027.6 OAG07394.1 - 0.13 12.0 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF3450 PF11932.8 OAG07395.1 - 0.0076 15.6 1.8 0.013 14.8 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ADIP PF11559.8 OAG07395.1 - 0.012 15.7 2.3 0.012 15.7 2.3 2.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 OAG07395.1 - 0.032 14.2 0.9 0.032 14.2 0.9 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TolA_bind_tri PF16331.5 OAG07395.1 - 0.059 13.5 1.4 0.13 12.3 1.4 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Herpes_UL51 PF04540.13 OAG07395.1 - 0.073 12.8 2.3 0.27 10.9 0.3 2.1 2 0 0 2 2 2 0 Herpesvirus UL51 protein FlaC_arch PF05377.11 OAG07395.1 - 0.13 12.7 0.2 2.2 8.7 0.0 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 OAG07395.1 - 0.13 12.8 7.7 0.11 13.0 2.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region YscO PF07321.12 OAG07395.1 - 0.14 12.1 11.3 0.12 12.3 3.6 2.3 2 1 0 2 2 2 0 Type III secretion protein YscO Cnn_1N PF07989.11 OAG07395.1 - 0.2 11.8 3.8 0.16 12.2 1.1 2.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 YabA PF06156.13 OAG07395.1 - 0.21 12.2 1.5 0.32 11.7 0.4 1.7 1 1 1 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OAG07395.1 - 0.27 11.3 5.4 0.091 12.8 3.0 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 OAG07395.1 - 0.43 10.8 5.0 0.16 12.2 1.2 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 PRKG1_interact PF15898.5 OAG07395.1 - 0.8 10.6 6.1 1.3 9.9 0.6 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 OAG07395.1 - 0.98 9.5 10.6 0.15 12.1 3.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 OAG07395.1 - 1.1 9.7 7.3 0.21 12.0 3.1 1.9 2 1 0 2 2 2 0 Cell division protein ZapB OEP PF02321.18 OAG07395.1 - 1.6 8.5 11.2 3.1 7.6 5.6 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein CENP-H PF05837.12 OAG07395.1 - 1.7 9.1 6.8 0.64 10.5 3.1 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) HSCB_C PF07743.13 OAG07395.1 - 6.6 7.3 9.4 0.83 10.2 4.3 2.0 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Ank_2 PF12796.7 OAG07396.1 - 2.6e-24 85.6 4.9 2.7e-14 53.5 0.2 4.7 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAG07396.1 - 3.4e-17 62.0 0.3 0.00097 19.5 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OAG07396.1 - 1.2e-15 57.7 0.5 2.2e-06 28.1 0.0 5.3 2 1 4 6 6 6 4 Ankyrin repeats (many copies) HET PF06985.11 OAG07396.1 - 1e-10 42.1 9.5 9.5e-09 35.8 3.0 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 OAG07396.1 - 2.4e-10 39.8 0.9 0.0037 17.6 0.0 6.8 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OAG07396.1 - 6.9e-08 32.6 2.2 0.0038 17.5 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.12 OAG07396.1 - 4.7e-06 26.6 0.2 1.8e-05 24.7 0.2 2.0 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 OAG07396.1 - 1.5e-05 24.4 5.3 0.00021 20.7 5.0 2.2 1 1 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 OAG07396.1 - 0.00059 20.3 0.4 0.0072 16.7 0.2 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG07396.1 - 0.0012 19.1 0.0 0.006 16.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain Ribosomal_L38e PF01781.18 OAG07396.1 - 0.026 14.6 0.7 0.93 9.6 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L38e protein family Chitin_synth_1 PF01644.17 OAG07397.1 - 1.3e-66 223.5 0.0 1.9e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAG07397.1 - 2.9e-26 91.2 0.0 5.5e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG07397.1 - 1.3e-23 83.4 0.3 3.5e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG07397.1 - 2.8e-09 37.2 0.1 2.8e-09 37.2 0.1 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 NAD_binding_4 PF07993.12 OAG07398.1 - 1.8e-22 79.7 0.0 2.7e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAG07398.1 - 1e-09 38.2 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG07398.1 - 0.03 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AnkUBD PF18418.1 OAG07399.1 - 0.098 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin ubiquitin-binding domain Wzy_C PF04932.15 OAG07399.1 - 0.18 11.4 2.0 0.39 10.3 0.0 2.3 3 0 0 3 3 3 0 O-Antigen ligase DUF2062 PF09835.9 OAG07399.1 - 0.21 11.4 8.8 0.15 11.9 3.9 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF4064 PF13273.6 OAG07399.1 - 0.28 11.5 5.0 0.28 11.5 0.1 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF4064) SnoaL_4 PF13577.6 OAG07401.1 - 3e-59 198.7 3.2 7.9e-23 81.0 0.3 3.3 3 0 0 3 3 3 3 SnoaL-like domain SnoaL_2 PF12680.7 OAG07401.1 - 0.018 15.7 0.3 1.2 9.8 0.0 3.2 3 1 0 3 3 3 0 SnoaL-like domain MIP PF00230.20 OAG07402.1 - 5.5e-16 59.0 0.7 7.5e-16 58.5 0.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Dynamin_N PF00350.23 OAG07403.1 - 2.9e-27 95.8 0.0 1e-26 94.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 OAG07403.1 - 5.5e-21 75.0 0.4 1.6e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 OAG07403.1 - 5e-05 23.4 0.0 0.00017 21.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 OAG07403.1 - 0.00011 22.3 0.0 0.00054 20.1 0.0 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_21 PF13304.6 OAG07403.1 - 0.017 14.9 0.1 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG07403.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.8 2 2 0 2 2 2 0 AAA ATPase domain RNase_H2-Ydr279 PF09468.10 OAG07403.1 - 0.054 13.7 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain AAA_29 PF13555.6 OAG07403.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG07403.1 - 0.06 13.9 0.3 0.38 11.3 0.0 2.6 4 0 0 4 4 3 0 AAA domain AAA_16 PF13191.6 OAG07403.1 - 0.072 13.5 0.2 0.55 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 OAG07403.1 - 0.1 12.8 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OAG07403.1 - 1.7 9.1 12.2 2.1 8.8 0.0 4.0 2 1 0 3 3 3 0 AAA domain RhgB_N PF09284.10 OAG07404.1 - 7.5e-80 268.1 2.7 1e-79 267.7 2.7 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 OAG07404.1 - 1.3e-32 112.9 0.3 5.7e-32 110.9 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 OAG07404.1 - 7.1e-17 61.0 1.7 7.1e-17 61.0 1.7 2.5 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OAG07404.1 - 1.1e-05 25.5 1.6 3.3e-05 24.1 0.3 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OAG07404.1 - 0.017 15.1 0.1 0.017 15.1 0.1 2.2 3 0 0 3 3 3 0 CarboxypepD_reg-like domain DUF2012 PF09430.10 OAG07404.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) TPPII PF12580.8 OAG07404.1 - 0.24 10.8 0.0 0.48 9.9 0.0 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II Peptidase_S9 PF00326.21 OAG07406.1 - 0.00034 20.1 0.5 0.00068 19.2 0.3 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 OAG07406.1 - 0.00041 20.1 0.1 0.0014 18.3 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 OAG07406.1 - 0.0071 15.9 0.1 0.0071 15.9 0.1 1.5 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 OAG07406.1 - 0.073 13.7 0.3 0.14 12.7 0.2 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PHO4 PF01384.20 OAG07407.1 - 4.3e-101 338.3 10.5 5.4e-101 338.0 10.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family Barttin PF15462.6 OAG07407.1 - 0.26 11.0 0.7 0.42 10.4 0.7 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) adh_short PF00106.25 OAG07408.1 - 2.9e-48 163.9 0.1 3.8e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07408.1 - 2.5e-38 131.9 0.0 3.1e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07408.1 - 1e-14 54.9 0.3 1.6e-14 54.2 0.3 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG07408.1 - 0.00096 19.4 0.4 0.0016 18.7 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG07408.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG07408.1 - 0.018 14.0 0.2 0.027 13.5 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 OAG07408.1 - 0.027 14.3 0.6 0.049 13.5 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OAG07408.1 - 0.035 13.4 0.4 0.42 9.9 0.1 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 OAG07408.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_25 PF13649.6 OAG07408.1 - 0.14 12.9 0.3 0.33 11.7 0.3 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.24 OAG07409.1 - 5.1e-83 279.4 31.0 5.9e-83 279.2 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07409.1 - 9.2e-14 51.1 39.8 2.1e-11 43.4 13.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF997 PF06196.12 OAG07411.1 - 2.4 8.3 5.2 3.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Coa1 PF08695.10 OAG07412.1 - 9e-40 135.1 0.0 1.4e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.11 OAG07412.1 - 0.18 11.7 0.0 2.3 8.1 0.0 2.0 2 0 0 2 2 2 0 TIM21 DUF1977 PF09320.11 OAG07413.1 - 6.2e-22 77.8 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 OAG07413.1 - 4.8e-21 74.7 2.7 2.4e-20 72.4 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain Aim19 PF10315.9 OAG07414.1 - 2.9e-05 24.3 0.1 3.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Ufd2P_core PF10408.9 OAG07415.1 - 1.5e-200 668.0 9.3 1.8e-200 667.7 9.3 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OAG07415.1 - 6.8e-24 83.8 0.4 2e-23 82.3 0.4 1.8 1 0 0 1 1 1 1 U-box domain DUF2203 PF09969.9 OAG07415.1 - 0.12 13.1 1.2 3.3 8.5 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FliJ PF02050.16 OAG07415.1 - 0.17 12.1 4.6 0.1 12.8 1.7 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Spc24 PF08286.11 OAG07415.1 - 4 7.7 5.3 23 5.3 0.9 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IBV_3C PF03620.13 OAG07416.1 - 0.046 14.2 0.1 0.57 10.7 0.0 2.3 2 0 0 2 2 2 0 IBV 3C protein Ras PF00071.22 OAG07418.1 - 9.5e-56 187.9 0.0 1.1e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG07418.1 - 7.1e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG07418.1 - 6.9e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG07418.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit baeRF_family3 PF18845.1 OAG07418.1 - 0.023 14.9 0.1 0.11 12.8 0.1 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 NB-ARC PF00931.22 OAG07418.1 - 0.039 13.1 0.5 0.45 9.7 0.0 2.3 2 1 1 3 3 3 0 NB-ARC domain Gtr1_RagA PF04670.12 OAG07418.1 - 0.082 12.2 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Asp PF00026.23 OAG07419.1 - 2.5e-61 207.8 3.0 2.5e-61 207.8 3.0 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG07419.1 - 6.7e-07 29.7 1.1 6.7e-07 29.7 1.1 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAG07419.1 - 0.026 14.3 0.1 0.29 10.9 0.0 2.1 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal DUF1712 PF08217.11 OAG07420.1 - 5.4e-17 61.5 0.0 8.4e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DUF3261 PF11659.8 OAG07420.1 - 0.069 13.0 0.1 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3261) Formyl_trans_N PF00551.19 OAG07421.1 - 6.3e-24 84.7 0.0 1.1e-23 83.9 0.0 1.4 1 1 0 1 1 1 1 Formyl transferase Tcf25 PF04910.14 OAG07422.1 - 2.5e-81 273.5 0.0 3.4e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_6 PF13174.6 OAG07422.1 - 0.0022 18.5 0.1 0.022 15.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Nop53 PF07767.11 OAG07422.1 - 0.078 12.4 14.4 0.12 11.7 14.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TPR_14 PF13428.6 OAG07422.1 - 0.41 11.6 4.5 1.2 10.2 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TFIIF_alpha PF05793.12 OAG07422.1 - 0.7 8.4 18.6 1 7.8 18.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VPS11_C PF12451.8 OAG07422.1 - 5.8 7.2 5.3 21 5.4 1.4 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal PP2C PF00481.21 OAG07423.1 - 1e-39 136.8 0.0 1.6e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OAG07423.1 - 0.0019 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OAG07423.1 - 0.018 15.0 0.2 0.75 9.7 0.0 2.9 4 0 0 4 4 4 0 Stage II sporulation protein E (SpoIIE) 4F5 PF04419.14 OAG07425.1 - 1.3e-11 45.1 12.1 1.3e-11 45.1 12.1 2.2 2 1 0 2 2 2 1 4F5 protein family Cu_bind_like PF02298.17 OAG07426.1 - 0.0014 18.6 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 OAG07426.1 - 0.0031 17.9 0.4 0.0067 16.9 0.4 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Forkhead_N PF08430.12 OAG07426.1 - 2.4 8.8 13.4 6 7.5 2.3 2.4 2 0 0 2 2 2 0 Forkhead N-terminal region SMN PF06003.12 OAG07427.1 - 4.6e-08 32.7 1.9 0.0028 17.0 0.1 2.2 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.22 OAG07428.1 - 5.9e-12 45.2 0.2 2.2e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.6 OAG07430.1 - 5.5e-07 29.9 0.0 1.5e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAG07430.1 - 8.5e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG07430.1 - 5.4e-05 23.6 0.0 0.00017 22.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 OAG07430.1 - 0.016 15.6 0.5 0.11 13.0 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2353 PF09789.9 OAG07430.1 - 0.04 13.3 0.8 0.15 11.4 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Helo_like_N PF17111.5 OAG07430.1 - 1.8 7.8 6.2 4 6.7 2.9 2.9 3 1 0 3 3 3 0 Fungal N-terminal domain of STAND proteins Sec23_trunk PF04811.15 OAG07432.1 - 4.6e-78 262.1 0.0 6.8e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OAG07432.1 - 1.1e-27 96.6 0.0 2.6e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OAG07432.1 - 2.2e-25 88.4 0.8 4.8e-25 87.4 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAG07432.1 - 3.7e-15 55.7 4.6 7e-15 54.8 4.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAG07432.1 - 2.5e-14 52.9 0.0 2.7e-12 46.4 0.0 2.5 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAG07432.1 - 0.11 11.9 0.4 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cyto_heme_lyase PF01265.17 OAG07433.1 - 5.6e-40 137.8 12.0 4.6e-38 131.5 12.0 3.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase MDD_C PF18376.1 OAG07434.1 - 1.1e-66 224.2 0.0 1.5e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OAG07434.1 - 1.1e-08 35.1 0.9 3e-08 33.8 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Syntaxin_2 PF14523.6 OAG07436.1 - 4.9e-25 87.8 3.4 1.3e-23 83.3 0.1 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 OAG07436.1 - 6.9e-14 51.6 1.2 6.9e-14 51.6 1.2 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OAG07436.1 - 1.6e-07 31.2 12.1 2.6e-05 24.0 12.1 3.0 1 1 0 1 1 1 1 Syntaxin Nre_C PF04895.12 OAG07436.1 - 0.00092 19.1 0.0 0.00092 19.1 0.0 2.2 3 0 0 3 3 3 1 Archaeal Nre, C-terminal Synaptobrevin PF00957.21 OAG07436.1 - 0.0039 17.0 0.4 0.0039 17.0 0.4 2.3 3 0 0 3 3 3 1 Synaptobrevin TMPIT PF07851.13 OAG07436.1 - 0.028 13.7 5.3 0.062 12.5 5.2 1.7 1 1 0 1 1 1 0 TMPIT-like protein ODV-E18 PF10717.9 OAG07436.1 - 0.057 13.3 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF883 PF05957.13 OAG07436.1 - 0.073 13.7 0.2 0.073 13.7 0.2 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Amnionless PF14828.6 OAG07436.1 - 0.15 10.9 3.4 0.22 10.3 3.4 1.4 1 1 0 1 1 1 0 Amnionless Prominin PF05478.11 OAG07436.1 - 0.19 9.7 4.1 0.28 9.1 4.1 1.3 1 1 0 1 1 1 0 Prominin DUF5345 PF17280.2 OAG07436.1 - 0.51 10.4 0.1 0.51 10.4 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5345) ISG65-75 PF11727.8 OAG07436.1 - 1.1 8.4 7.0 1.5 8.0 0.7 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein Orf78 PF06024.12 OAG07436.1 - 1.2 9.5 4.6 0.36 11.2 0.3 2.1 2 1 0 2 2 2 0 Orf78 (ac78) Spectrin PF00435.21 OAG07436.1 - 2.1 8.9 10.7 6.2 7.4 9.3 2.3 1 1 2 3 3 3 0 Spectrin repeat DUF131 PF01998.17 OAG07436.1 - 4.9 6.9 5.4 11 5.7 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF131 YtxH PF12732.7 OAG07436.1 - 5.2 7.7 7.1 40 4.8 4.1 3.0 2 1 0 2 2 2 0 YtxH-like protein Ndc1_Nup PF09531.10 OAG07437.1 - 4.8e-154 514.4 0.2 5.5e-154 514.2 0.2 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup YtxH PF12732.7 OAG07437.1 - 0.029 14.9 0.1 0.089 13.3 0.0 1.9 2 0 0 2 2 2 0 YtxH-like protein Peptidase_Prp PF04327.12 OAG07437.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Cysteine protease Prp TarH PF02203.15 OAG07437.1 - 0.13 12.1 0.2 0.84 9.5 0.1 2.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue 4HB_MCP_1 PF12729.7 OAG07437.1 - 0.15 11.6 0.0 0.43 10.1 0.1 1.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction SurE PF01975.17 OAG07438.1 - 2.7e-34 118.7 4.4 3.6e-34 118.3 4.4 1.2 1 0 0 1 1 1 1 Survival protein SurE Pkinase PF00069.25 OAG07439.1 - 2e-14 53.6 0.0 1.2e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07439.1 - 1.8e-08 34.0 0.0 3.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 OAG07439.1 - 2.3e-06 27.3 4.4 0.47 10.8 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 OAG07439.1 - 4.6e-06 26.8 0.3 0.0005 20.1 0.0 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG07439.1 - 0.0023 18.4 0.1 3.2 8.3 0.2 3.5 3 0 0 3 3 3 1 HEAT-like repeat Kinase-like PF14531.6 OAG07439.1 - 0.0037 16.6 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 OAG07439.1 - 0.0084 16.5 1.7 0.21 12.0 0.5 3.3 2 1 2 4 4 4 2 HEAT repeats CLASP_N PF12348.8 OAG07439.1 - 0.022 14.3 0.2 16 5.0 0.1 2.9 1 1 2 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 OAG07439.1 - 0.075 13.6 0.0 6.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Ion_trans PF00520.31 OAG07440.1 - 0.001 18.3 0.2 0.0012 18.2 0.2 1.0 1 0 0 1 1 1 1 Ion transport protein Sugarporin_N PF11471.8 OAG07440.1 - 0.0036 17.2 0.2 0.0074 16.2 0.2 1.5 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension bZIP_1 PF00170.21 OAG07440.1 - 0.013 15.6 2.9 0.025 14.7 2.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor Shugoshin_N PF07558.11 OAG07440.1 - 0.076 12.9 2.8 0.076 12.9 2.8 1.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 OAG07440.1 - 0.74 9.9 7.7 0.27 11.3 4.9 1.7 2 0 0 2 2 2 0 Basic region leucine zipper RRM_1 PF00076.22 OAG07441.1 - 4e-16 58.6 0.0 6.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF724 PF05266.14 OAG07441.1 - 0.0042 16.9 2.1 0.0057 16.5 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Nup35_RRM_2 PF14605.6 OAG07441.1 - 0.053 13.5 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif UQ_con PF00179.26 OAG07442.1 - 9.6e-49 164.6 0.0 1.1e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG07442.1 - 0.00035 20.3 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG07442.1 - 0.0054 17.0 1.8 0.0098 16.2 1.8 1.7 1 1 0 1 1 1 1 RWD domain Pex19 PF04614.12 OAG07443.1 - 6.2e-69 232.5 8.2 6.8e-69 232.3 8.2 1.0 1 0 0 1 1 1 1 Pex19 protein family ABC_tran_Xtn PF12848.7 OAG07443.1 - 0.17 12.0 5.2 0.71 9.9 0.4 2.4 2 1 0 2 2 2 0 ABC transporter GET2 PF08690.10 OAG07443.1 - 1.5 8.4 8.9 1.4 8.5 4.8 2.4 1 1 1 2 2 2 0 GET complex subunit GET2 E2F_CC-MB PF16421.5 OAG07444.1 - 3.9 7.9 9.5 0.46 10.9 4.4 2.1 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain DUF5344 PF17279.2 OAG07446.1 - 0.29 11.7 2.2 4.1 8.1 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Glyco_hydro_76 PF03663.14 OAG07449.1 - 3.7e-40 138.6 2.6 3.7e-40 138.6 2.6 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG07449.1 - 4e-07 29.4 0.5 0.0026 16.9 0.0 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 JmjC PF02373.22 OAG07450.1 - 1.5e-10 41.5 0.7 1.7e-09 38.1 0.7 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 OAG07450.1 - 2.7e-07 30.7 7.9 2.7e-07 30.7 7.9 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 OAG07450.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.18 OAG07451.1 - 5.9e-45 153.5 20.0 8e-45 153.1 20.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF386 PF04074.12 OAG07452.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 YhcH/YjgK/YiaL GFA PF04828.14 OAG07453.1 - 3.3e-15 56.2 0.1 5.4e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L31e PF01198.19 OAG07454.1 - 5.1e-41 138.8 0.8 6.5e-41 138.5 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.18 OAG07454.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel zinc_ribbon_6 PF14599.6 OAG07455.1 - 3.8e-24 84.5 2.8 3.8e-24 84.5 2.8 4.9 5 2 1 6 6 6 1 Zinc-ribbon zf-CHY PF05495.12 OAG07455.1 - 2.3e-18 66.4 24.9 2.3e-18 66.4 24.9 3.3 3 0 0 3 3 3 2 CHY zinc finger zf-RING_2 PF13639.6 OAG07455.1 - 5.6e-09 36.2 5.0 5.6e-09 36.2 5.0 4.9 2 1 3 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG07455.1 - 5.7e-07 29.3 5.6 5.7e-07 29.3 5.6 4.5 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG07455.1 - 7.5e-06 25.9 2.8 7.5e-06 25.9 2.8 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG07455.1 - 7.5e-06 25.8 8.4 7.5e-06 25.8 8.4 5.9 3 3 1 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAG07455.1 - 0.0028 17.4 1.1 0.0028 17.4 1.1 3.3 4 0 0 4 4 4 1 RING-like zinc finger CENP-B_dimeris PF09026.10 OAG07455.1 - 7.3 7.1 18.0 17 5.9 18.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RasGEF PF00617.19 OAG07456.1 - 2e-51 174.7 0.0 3.9e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG07456.1 - 3.1e-15 56.3 0.0 1.4e-14 54.2 0.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 OAG07456.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG07456.1 - 0.00029 20.4 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HWE_HK PF07536.14 OAG07456.1 - 0.06 14.0 0.6 0.33 11.7 0.0 2.6 2 0 0 2 2 2 0 HWE histidine kinase DIE2_ALG10 PF04922.12 OAG07459.1 - 1.7e-121 406.2 5.7 2.1e-121 406.0 5.7 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 OAG07460.1 - 3.5e-30 104.7 0.0 5.7e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Glyco_hydro_61 PF03443.14 OAG07461.1 - 5e-48 163.8 0.0 8e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_3 PF07859.13 OAG07463.1 - 1.7e-14 54.2 0.0 4.5e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG07463.1 - 1.2e-06 28.1 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 OAG07463.1 - 7.6e-06 24.8 0.0 0.0017 17.1 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.20 OAG07463.1 - 0.13 11.9 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Chlorophyllase2 PF12740.7 OAG07463.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 OAG07464.1 - 3e-23 82.8 0.0 5.2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG07464.1 - 1.7e-20 73.3 0.0 2.4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase SLATT_fungal PF18142.1 OAG07465.1 - 8.4e-36 122.6 0.6 1e-35 122.3 0.6 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain LPD7 PF18821.1 OAG07465.1 - 0.18 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 DUF3405 PF11885.8 OAG07466.1 - 1.9e-227 755.9 1.4 2.3e-227 755.7 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) bZIP_2 PF07716.15 OAG07468.1 - 1.2e-12 47.7 12.4 2.3e-12 46.8 12.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper XhlA PF10779.9 OAG07468.1 - 0.01 16.0 2.8 0.023 14.9 2.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_1 PF00170.21 OAG07468.1 - 0.013 15.5 9.1 0.036 14.2 9.0 1.8 1 1 0 1 1 1 0 bZIP transcription factor Shugoshin_N PF07558.11 OAG07468.1 - 0.044 13.7 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 OAG07468.1 - 0.066 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family PspB PF06667.12 OAG07468.1 - 0.38 10.8 1.1 0.66 10.1 1.1 1.4 1 0 0 1 1 1 0 Phage shock protein B CENP-N PF05238.13 OAG07469.1 - 9.5e-130 433.6 0.0 1.1e-129 433.4 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like HHH PF00633.23 OAG07470.1 - 0.0063 16.3 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAG07470.1 - 0.077 13.6 0.0 0.88 10.2 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain zf-RING_2 PF13639.6 OAG07472.1 - 1.5e-07 31.6 7.2 1.5e-07 31.6 7.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG07472.1 - 0.00016 21.6 3.3 0.00016 21.6 3.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG07472.1 - 0.0018 18.5 5.0 0.0018 18.5 5.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain FANCL_C PF11793.8 OAG07472.1 - 0.0021 18.2 10.4 0.0021 18.2 10.4 2.5 2 1 0 2 2 2 1 FANCL C-terminal domain SWIM PF04434.17 OAG07472.1 - 0.013 15.1 0.4 0.033 13.8 0.4 1.7 1 0 0 1 1 1 0 SWIM zinc finger RINGv PF12906.7 OAG07472.1 - 0.037 14.1 7.3 0.077 13.1 7.3 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 OAG07472.1 - 0.11 12.4 7.7 0.23 11.4 7.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 OAG07472.1 - 0.13 12.3 5.3 0.3 11.1 5.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 OAG07472.1 - 0.96 9.3 9.4 2.3 8.1 9.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain adh_short PF00106.25 OAG07475.1 - 2.8e-33 115.0 0.0 4.8e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07475.1 - 2.1e-25 89.7 0.0 2.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07475.1 - 1.1e-05 25.4 0.0 0.00022 21.2 0.0 2.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG07475.1 - 0.0018 18.0 0.3 0.0035 17.1 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EMP24_GP25L PF01105.24 OAG07476.1 - 3.2e-48 164.1 0.1 3.7e-48 163.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HXXSHH PF07586.11 OAG07476.1 - 0.017 14.7 0.2 0.023 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF1940 PF09155.10 OAG07476.1 - 0.065 13.3 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) CENP-B_dimeris PF09026.10 OAG07480.1 - 0.31 11.5 9.6 0.51 10.8 9.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAG07480.1 - 1.1 7.2 8.1 1.5 6.8 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 OAG07480.1 - 1.7 7.8 6.6 2.2 7.4 6.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein IRF-3 PF10401.9 OAG07481.1 - 0.0085 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 zf-Sec23_Sec24 PF04810.15 OAG07483.1 - 0.012 15.6 0.7 3.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF836 PF05768.14 OAG07483.1 - 0.099 13.1 0.1 6.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) SANT_DAMP1_like PF16282.5 OAG07484.1 - 5.6e-28 97.0 1.4 1.4e-27 95.7 1.4 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Nic96 PF04097.14 OAG07484.1 - 0.0078 14.7 0.2 0.015 13.8 0.2 1.3 1 0 0 1 1 1 1 Nup93/Nic96 DMAP1 PF05499.12 OAG07484.1 - 0.009 15.9 2.1 0.089 12.7 0.4 2.4 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 OAG07484.1 - 0.02 15.1 0.0 0.13 12.5 0.0 2.4 2 1 0 2 2 2 0 Myb-like DNA-binding domain CENP-B_dimeris PF09026.10 OAG07484.1 - 3.6 8.0 12.1 10 6.6 12.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 OAG07485.1 - 1.3e-27 96.9 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07485.1 - 1e-14 54.5 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG07485.1 - 6e-07 28.6 0.0 1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Nucleoporin_C PF03177.14 OAG07487.1 - 6.2e-123 411.6 13.2 8.1e-123 411.2 13.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 OAG07487.1 - 9e-39 133.4 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Death_2 PF14786.6 OAG07487.1 - 0.043 13.8 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Tube Death domain HABP4_PAI-RBP1 PF04774.15 OAG07488.1 - 0.019 15.8 5.7 0.033 15.0 5.7 1.5 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family CIAPIN1 PF05093.13 OAG07489.1 - 4.7e-43 145.8 4.5 7.1e-43 145.2 4.5 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 OAG07489.1 - 9.3e-38 129.4 0.0 1.2e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus He_PIG PF05345.12 OAG07490.1 - 3.6e-17 62.3 10.7 6.5e-06 26.2 1.3 4.8 4 0 0 4 4 4 4 Putative Ig domain TGF_beta_GS PF08515.12 OAG07491.1 - 0.16 11.5 0.7 0.16 11.5 0.7 1.6 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif LigB PF02900.18 OAG07492.1 - 5.3e-28 97.8 0.0 5.8e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NOG1 PF06858.14 OAG07492.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DEAD PF00270.29 OAG07493.1 - 3.4e-17 62.8 0.0 5.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG07493.1 - 2e-14 53.9 0.0 8.5e-13 48.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAG07493.1 - 3.9e-13 49.9 2.6 9.9e-13 48.6 2.6 1.7 1 0 0 1 1 1 1 RecQ zinc-binding SQS_PSY PF00494.19 OAG07493.1 - 0.026 14.0 0.6 0.12 11.8 0.1 2.2 2 0 0 2 2 2 0 Squalene/phytoene synthase DUF1336 PF07059.12 OAG07493.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) UBA PF00627.31 OAG07494.1 - 9e-06 25.5 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 OAG07494.1 - 2.1e-05 24.6 0.1 0.00019 21.5 0.0 2.5 2 0 0 2 2 2 1 UBX domain DUF572 PF04502.13 OAG07494.1 - 0.021 14.4 18.3 0.032 13.9 18.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SprA-related PF12118.8 OAG07494.1 - 0.022 13.9 20.4 0.035 13.2 20.4 1.3 1 0 0 1 1 1 0 SprA-related family zf-C2H2_2 PF12756.7 OAG07494.1 - 0.047 14.0 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OAG07494.1 - 0.12 12.9 0.7 0.25 11.9 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type SOBP PF15279.6 OAG07494.1 - 1.7 9.2 8.3 2.3 8.8 8.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 OAG07494.1 - 3.6 5.8 15.1 4.1 5.6 15.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 OAG07494.1 - 4.3 5.3 11.9 4.7 5.2 11.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Motile_Sperm PF00635.26 OAG07495.1 - 4e-28 97.4 0.2 9.4e-28 96.2 0.1 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.8 OAG07495.1 - 0.072 13.3 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DASH_Dad1 PF08649.10 OAG07495.1 - 0.13 12.5 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad1 Asn_synthase PF00733.21 OAG07496.1 - 3.1e-93 313.3 0.1 1.1e-53 183.2 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OAG07496.1 - 4.9e-36 123.4 0.0 8.7e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAG07496.1 - 1.3e-26 93.4 0.0 2.3e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAG07496.1 - 8.7e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 OAG07496.1 - 0.0075 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 NAD synthase PQ-loop PF04193.14 OAG07497.1 - 2.8e-37 126.3 5.2 1.5e-18 66.3 0.1 2.8 2 1 1 3 3 3 2 PQ loop repeat TMEM132D_C PF15706.5 OAG07497.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Mid2 PF04478.12 OAG07498.1 - 0.00031 20.6 0.4 0.00086 19.2 0.4 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF2633 PF11119.8 OAG07498.1 - 0.16 11.9 0.3 0.32 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Ndc1_Nup PF09531.10 OAG07498.1 - 1.1 7.8 7.8 1.5 7.4 7.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 OAG07498.1 - 5.3 6.9 11.8 6.9 6.6 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIIAH PF12685.7 OAG07498.1 - 6.7 6.5 13.2 16 5.3 13.2 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF3010 PF11215.8 OAG07499.1 - 0.038 14.3 0.1 0.056 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) Ydc2-catalyt PF09159.10 OAG07500.1 - 2.1e-61 208.1 0.9 2.1e-61 208.1 0.9 1.7 2 0 0 2 2 2 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 OAG07500.1 - 0.0032 17.6 0.2 1.2 9.2 0.0 3.2 3 0 0 3 3 3 1 Poxvirus A22 protein OrfB_IS605 PF01385.19 OAG07500.1 - 0.084 13.1 0.5 0.57 10.4 0.0 2.6 3 0 0 3 3 3 0 Probable transposase Fungal_trans PF04082.18 OAG07501.1 - 9.7e-20 70.7 3.9 1.6e-19 70.0 3.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 OAG07502.1 - 1.5e-19 70.8 0.0 1.7e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Abhydrolase_3 PF07859.13 OAG07503.1 - 1.6e-51 175.1 0.0 4.3e-51 173.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG07503.1 - 0.00015 20.8 0.0 0.0005 19.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG07503.1 - 0.0029 17.1 0.1 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAG07503.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase PTR2 PF00854.21 OAG07504.1 - 2.6e-80 270.2 13.7 3.5e-80 269.8 13.7 1.1 1 0 0 1 1 1 1 POT family CTP_transf_like PF01467.26 OAG07505.1 - 2.7e-09 37.3 0.0 4.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 OAG07505.1 - 0.015 15.2 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 FAD synthetase Beta-lactamase PF00144.24 OAG07507.1 - 4.1e-28 98.6 0.0 7.3e-28 97.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase TauD PF02668.16 OAG07507.1 - 0.0071 16.2 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family bZIP_1 PF00170.21 OAG07508.1 - 5.8e-05 23.1 10.3 0.00014 21.9 10.3 1.6 1 1 0 1 1 1 1 bZIP transcription factor CCDC92 PF14916.6 OAG07508.1 - 0.00065 19.4 0.2 0.0011 18.6 0.2 1.3 1 0 0 1 1 1 1 Coiled-coil domain of unknown function BLOC1_2 PF10046.9 OAG07508.1 - 0.0071 16.6 2.0 1.4 9.2 0.4 2.2 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 OAG07508.1 - 0.04 13.3 1.1 0.058 12.7 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 OAG07508.1 - 0.45 10.6 13.1 8 6.6 0.1 2.2 1 1 1 2 2 2 0 Basic region leucine zipper BCL9 PF11502.8 OAG07508.1 - 4.3 7.2 9.1 20 5.1 7.7 2.4 1 1 1 2 2 2 0 B-cell lymphoma 9 protein adh_short PF00106.25 OAG07509.1 - 8.2e-21 74.4 2.9 1.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07509.1 - 5.8e-14 52.2 2.1 3.1e-07 30.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase A_deaminase PF00962.22 OAG07510.1 - 1.8e-35 122.8 0.0 2.2e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 OAG07511.1 - 1.1e-30 106.8 33.6 1.5e-30 106.4 33.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG07511.1 - 1.2e-06 28.1 2.3 1.2e-06 28.1 2.3 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3593 PF12159.8 OAG07511.1 - 0.12 12.5 1.3 0.37 10.9 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Cu_amine_oxid PF01179.20 OAG07512.1 - 7.7e-122 407.1 1.4 9.5e-122 406.8 1.4 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 OAG07512.1 - 2.4e-10 40.0 0.1 6.7e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 OAG07512.1 - 0.00067 19.8 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Fungal_trans_2 PF11951.8 OAG07513.1 - 9.4e-22 77.3 3.2 1.1e-21 77.2 3.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_20 PF12147.8 OAG07513.1 - 0.063 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Helicase_C_2 PF13307.6 OAG07513.1 - 0.097 12.8 0.1 0.19 11.9 0.0 1.5 2 0 0 2 2 2 0 Helicase C-terminal domain T5orf172 PF10544.9 OAG07516.1 - 8.8e-24 84.0 2.4 2.9e-23 82.4 2.4 1.9 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAG07516.1 - 8.7e-18 64.8 2.6 2.4e-17 63.4 2.6 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 GIY-YIG PF01541.24 OAG07516.1 - 0.019 15.2 0.1 0.039 14.2 0.1 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain Shugoshin_C PF07557.11 OAG07517.1 - 5.3e-12 45.3 6.5 5.3e-12 45.3 6.5 3.1 4 0 0 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.11 OAG07517.1 - 1.4e-10 40.9 5.1 1.4e-10 40.9 5.1 1.7 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Tli4_N PF18443.1 OAG07517.1 - 0.05 14.0 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain TMCO5 PF14992.6 OAG07517.1 - 0.14 11.8 1.4 0.33 10.5 1.4 1.6 1 0 0 1 1 1 0 TMCO5 family GIT_CC PF16559.5 OAG07517.1 - 0.43 10.5 3.6 0.37 10.7 1.3 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Mod_r PF07200.13 OAG07517.1 - 8.3 6.5 12.5 0.12 12.5 3.0 2.7 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DASH_Dad2 PF08654.10 OAG07518.1 - 2.2e-34 117.8 0.4 2.7e-34 117.6 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Rogdi_lz PF10259.9 OAG07518.1 - 0.054 13.0 0.5 0.061 12.8 0.5 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DASH_Duo1 PF08651.10 OAG07518.1 - 0.072 12.9 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF2555 PF10742.9 OAG07518.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) PPI_Ypi1 PF07491.11 OAG07519.1 - 6.5e-25 86.7 6.9 2.8e-24 84.7 6.9 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.14 OAG07519.1 - 0.082 11.2 6.7 0.085 11.1 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.14 OAG07519.1 - 0.12 11.8 7.9 0.16 11.4 7.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.25 OAG07521.1 - 8.8e-57 192.5 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07521.1 - 3.4e-28 98.7 0.0 5.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG07521.1 - 3.3e-07 29.9 0.0 4.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG07521.1 - 0.00027 20.9 0.1 0.72 9.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAG07521.1 - 0.064 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RGS PF00615.19 OAG07524.1 - 1.6e-30 105.8 0.1 5.1e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 OAG07524.1 - 4.2e-18 65.2 0.0 7.8e-15 54.7 0.0 3.1 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1304 PF06993.12 OAG07524.1 - 0.21 11.6 0.1 0.43 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Pdase_M17_N2 PF18295.1 OAG07525.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.2 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 DUF5531 PF17671.1 OAG07526.1 - 0.14 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5531) MFS_1 PF07690.16 OAG07529.1 - 2e-37 129.0 59.7 1.2e-27 96.8 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG07529.1 - 6.6e-11 41.7 37.4 5.3e-07 28.9 12.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 OAG07529.1 - 1.4e-09 37.7 22.3 1.9e-09 37.3 22.3 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 OAG07529.1 - 1.1e-06 27.8 19.0 4.2e-05 22.6 18.2 2.1 1 1 0 1 1 1 1 MFS_1 like family Glyco_hydro_36 PF17167.4 OAG07530.1 - 8.2e-67 225.7 0.2 1.8e-66 224.6 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 OAG07530.1 - 5.2e-30 104.7 0.2 8.1e-30 104.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 GDE_C PF06202.14 OAG07530.1 - 3.4e-06 26.2 0.0 7e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid6H PF17389.2 OAG07530.1 - 8.3e-05 22.0 0.1 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_65C PF03633.15 OAG07530.1 - 0.0018 18.1 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Reg_prop PF07494.11 OAG07530.1 - 0.14 12.4 0.1 0.45 10.9 0.1 1.9 1 0 0 1 1 1 0 Two component regulator propeller zf-C2H2_4 PF13894.6 OAG07532.1 - 0.12 13.3 0.3 0.12 13.3 0.3 5.3 5 1 0 5 5 5 0 C2H2-type zinc finger C1_4 PF07975.12 OAG07532.1 - 0.41 10.9 9.9 1.1 9.6 9.2 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain BPL_LplA_LipB PF03099.19 OAG07535.1 - 0.0004 20.3 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 OAG07535.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus FAD_binding_3 PF01494.19 OAG07536.1 - 3.2e-40 138.5 0.0 3.8e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG07536.1 - 8.3e-06 25.6 0.0 0.0041 16.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG07536.1 - 0.00051 19.2 0.4 0.11 11.5 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 OAG07536.1 - 0.0085 15.4 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG07536.1 - 0.03 14.9 0.1 8.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.26 OAG07537.1 - 3.9e-25 88.5 0.1 7.6e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG07537.1 - 7.3e-14 51.6 0.0 1.8e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OAG07537.1 - 0.0081 16.0 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 OAG07537.1 - 0.08 12.9 0.0 0.27 11.2 0.0 1.9 1 1 0 1 1 1 0 GHKL domain Tup_N PF08581.10 OAG07538.1 - 0.00026 21.2 3.2 0.00048 20.4 2.0 1.9 1 1 1 2 2 2 1 Tup N-terminal Phage_GP20 PF06810.11 OAG07538.1 - 0.0013 18.6 1.3 0.0013 18.6 1.3 1.6 2 0 0 2 2 1 1 Phage minor structural protein GP20 COG2 PF06148.11 OAG07538.1 - 0.0015 18.6 0.8 0.0024 18.0 0.8 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Tmemb_cc2 PF10267.9 OAG07538.1 - 0.0016 17.7 4.3 0.0021 17.3 4.3 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Golgin_A5 PF09787.9 OAG07538.1 - 0.0022 17.5 0.4 0.0044 16.5 0.4 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 OAG07538.1 - 0.0033 17.5 4.4 0.0069 16.4 4.4 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OAG07538.1 - 0.0083 15.0 3.3 0.016 14.1 3.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 OAG07538.1 - 0.012 15.8 2.2 0.029 14.6 2.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 OAG07538.1 - 0.014 15.6 3.4 0.014 15.6 3.4 1.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 OAG07538.1 - 0.023 14.7 0.5 0.032 14.3 0.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 OAG07538.1 - 0.024 13.3 1.1 0.038 12.6 1.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A JIP_LZII PF16471.5 OAG07538.1 - 0.026 14.7 5.3 0.15 12.3 2.1 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II OmpH PF03938.14 OAG07538.1 - 0.065 13.6 0.8 0.065 13.6 0.8 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cauli_AT PF03233.13 OAG07538.1 - 0.068 13.1 0.1 0.068 13.1 0.1 1.6 2 0 0 2 2 2 0 Aphid transmission protein Zip PF02535.22 OAG07538.1 - 0.077 12.2 1.9 0.14 11.4 1.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3450 PF11932.8 OAG07538.1 - 0.077 12.3 1.1 0.082 12.2 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 OAG07538.1 - 0.11 12.5 0.7 0.19 11.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 OAG07538.1 - 0.17 12.3 7.4 0.11 12.9 1.8 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Macoilin PF09726.9 OAG07538.1 - 0.21 10.1 11.2 0.25 9.8 11.2 1.1 1 0 0 1 1 1 0 Macoilin family DivIC PF04977.15 OAG07538.1 - 0.95 9.3 5.5 2.4 8.0 1.3 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF812 PF05667.11 OAG07538.1 - 2.3 7.0 9.9 4.7 6.0 10.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Vfa1 PF08432.10 OAG07538.1 - 2.7 8.3 14.0 6.6 7.0 6.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GRAB PF10375.9 OAG07539.1 - 3.9e-09 36.1 0.1 1.2e-08 34.5 0.1 1.9 1 0 0 1 1 1 1 GRIP-related Arf-binding domain FliD_C PF07195.12 OAG07539.1 - 0.012 15.1 4.7 0.019 14.4 4.7 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.10 OAG07539.1 - 0.017 15.3 9.7 0.26 11.5 4.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family REGB_T4 PF10715.9 OAG07539.1 - 0.021 15.1 0.3 0.038 14.2 0.3 1.4 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB Gp58 PF07902.11 OAG07539.1 - 0.023 13.0 3.5 0.032 12.5 3.5 1.1 1 0 0 1 1 1 0 gp58-like protein Laminin_I PF06008.14 OAG07539.1 - 0.031 14.0 18.8 0.2 11.4 10.0 2.2 1 1 1 2 2 2 0 Laminin Domain I YscO PF07321.12 OAG07539.1 - 0.052 13.5 22.7 0.78 9.7 12.4 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO DUF3584 PF12128.8 OAG07539.1 - 0.11 10.0 14.3 0.14 9.6 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BST2 PF16716.5 OAG07539.1 - 0.13 12.8 17.8 0.41 11.3 9.8 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Macoilin PF09726.9 OAG07539.1 - 0.15 10.6 12.9 0.18 10.3 12.9 1.1 1 0 0 1 1 1 0 Macoilin family TPR_MLP1_2 PF07926.12 OAG07539.1 - 0.15 12.1 23.8 0.28 11.3 22.9 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4404 PF14357.6 OAG07539.1 - 0.21 12.3 13.4 0.1 13.2 3.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMF_DNA_bd PF12329.8 OAG07539.1 - 0.24 11.4 23.8 3.5 7.7 0.3 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 OAG07539.1 - 0.27 9.1 4.4 0.35 8.8 4.4 1.1 1 0 0 1 1 1 0 Prominin GAS PF13851.6 OAG07539.1 - 0.33 10.3 18.8 0.26 10.6 17.1 1.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 OAG07539.1 - 0.34 10.5 12.3 0.46 10.0 12.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit T3SSipB PF16535.5 OAG07539.1 - 0.4 11.1 13.2 1 9.8 13.1 1.7 1 1 0 1 1 1 0 Type III cell invasion protein SipB APG17 PF04108.12 OAG07539.1 - 0.48 9.5 12.9 0.87 8.6 12.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 She9_MDM33 PF05546.11 OAG07539.1 - 0.51 10.1 12.9 0.58 9.9 5.7 2.3 1 1 1 2 2 2 0 She9 / Mdm33 family Prefoldin PF02996.17 OAG07539.1 - 0.54 10.2 12.3 2.1 8.3 2.4 2.8 1 1 0 2 2 2 0 Prefoldin subunit Hemagglutinin PF00509.18 OAG07539.1 - 0.55 8.6 2.3 0.74 8.1 2.3 1.1 1 0 0 1 1 1 0 Haemagglutinin Cas_DxTHG PF09455.10 OAG07539.1 - 0.56 9.7 7.3 0.73 9.4 7.3 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family DUF1664 PF07889.12 OAG07539.1 - 0.61 10.1 7.0 0.37 10.8 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 OAG07539.1 - 0.65 8.5 7.3 1 7.8 7.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.12 OAG07539.1 - 0.8 9.7 5.2 0.52 10.3 2.0 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 OAG07539.1 - 0.91 10.1 13.9 0.31 11.6 10.0 2.3 2 1 1 3 3 2 0 Syntaxin 6, N-terminal Sec8_exocyst PF04048.14 OAG07539.1 - 1 9.2 9.6 0.077 12.9 2.1 2.3 2 1 1 3 3 2 0 Sec8 exocyst complex component specific domain MnmE_helical PF12631.7 OAG07539.1 - 1.1 9.4 8.3 1.7 8.8 8.3 1.3 1 0 0 1 1 1 0 MnmE helical domain Phage_Mu_Gam PF07352.12 OAG07539.1 - 1.1 9.1 16.6 3.7 7.5 6.3 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein LPP PF04728.13 OAG07539.1 - 1.4 9.4 9.9 1.7 9.1 2.7 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper AAA_13 PF13166.6 OAG07539.1 - 1.7 7.2 12.8 3 6.4 12.8 1.4 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 OAG07539.1 - 1.8 9.0 25.4 3.1 8.2 8.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 OAG07539.1 - 1.8 9.1 4.1 11 6.6 4.1 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 OAG07539.1 - 2.1 7.1 20.9 4 6.2 20.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 OAG07539.1 - 2.3 7.2 14.2 4.5 6.3 14.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ISG65-75 PF11727.8 OAG07539.1 - 3.2 6.9 11.7 2.4 7.3 9.6 1.6 1 1 1 2 2 2 0 Invariant surface glycoprotein Acetyltransf_11 PF13720.6 OAG07539.1 - 3.5 8.2 6.4 7.1 7.2 3.7 2.8 3 1 0 3 3 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Goodbye PF17109.5 OAG07539.1 - 3.8 8.0 6.4 7.1 7.1 0.6 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain LMBR1 PF04791.16 OAG07539.1 - 5.4 5.8 7.9 6.4 5.6 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rho_Binding PF08912.11 OAG07539.1 - 5.8 7.8 19.7 2.4 9.0 6.1 2.9 2 2 0 2 2 2 0 Rho Binding V_ATPase_I PF01496.19 OAG07539.1 - 6.8 4.5 6.9 8.3 4.2 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tho2 PF11262.8 OAG07539.1 - 6.9 5.8 13.2 0.27 10.4 4.5 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TMPIT PF07851.13 OAG07539.1 - 7.6 5.7 11.3 3.6 6.7 5.2 1.4 1 1 1 2 2 2 0 TMPIT-like protein OEP PF02321.18 OAG07539.1 - 7.7 6.3 19.1 7.6 6.3 17.4 1.7 1 1 0 1 1 1 0 Outer membrane efflux protein Snapin_Pallidin PF14712.6 OAG07539.1 - 8.1 6.9 14.5 5.7 7.4 3.3 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Muted PF14942.6 OAG07539.1 - 8.7 6.7 16.0 1.8 8.9 10.3 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein YlqD PF11068.8 OAG07539.1 - 8.9 6.7 16.6 3.9e+02 1.4 15.8 2.2 1 1 0 1 1 1 0 YlqD protein Med9 PF07544.13 OAG07539.1 - 9.2 6.4 13.8 0.39 10.8 3.0 2.8 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 OmpH PF03938.14 OAG07539.1 - 9.2 6.6 22.7 4.5 7.6 8.1 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Csm1_N PF18504.1 OAG07539.1 - 9.7 6.6 20.7 1.8 9.0 3.2 3.9 2 1 2 4 4 4 0 Csm1 N-terminal domain DUF4407 PF14362.6 OAG07539.1 - 9.9 5.4 17.9 34 3.7 17.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L32p PF01783.23 OAG07540.1 - 4.7e-13 49.2 1.4 4.7e-13 49.2 1.4 2.0 2 0 0 2 2 2 1 Ribosomal L32p protein family DUF2913 PF11140.8 OAG07540.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Septin PF00735.18 OAG07541.1 - 1e-112 376.0 0.5 1.3e-112 375.7 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAG07541.1 - 1.8e-08 34.5 0.0 3.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAG07541.1 - 1.3e-06 27.9 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 OAG07541.1 - 2.1e-06 27.4 0.2 0.0013 18.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG07541.1 - 1.3e-05 25.2 0.2 0.0001 22.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OAG07541.1 - 0.0015 18.6 0.2 1.5 8.9 0.1 2.6 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 OAG07541.1 - 0.0023 17.2 0.1 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 OAG07541.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG07541.1 - 0.0065 17.0 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 OAG07541.1 - 0.008 15.7 0.0 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 OAG07541.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 OAG07541.1 - 0.014 14.7 0.2 0.35 10.2 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG07541.1 - 0.041 14.1 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_3 PF01171.20 OAG07541.1 - 0.047 13.4 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 PP-loop family FtsK_SpoIIIE PF01580.18 OAG07541.1 - 0.059 12.7 0.1 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family SLATT_fungal PF18142.1 OAG07541.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Ras PF00071.22 OAG07541.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 Ras family G-alpha PF00503.20 OAG07541.1 - 0.12 11.5 0.9 0.25 10.4 0.9 1.8 1 1 0 1 1 1 0 G-protein alpha subunit T2SSE PF00437.20 OAG07541.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 OAG07541.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 OAG07541.1 - 0.2 10.8 0.3 0.69 9.0 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain Yae1_N PF09811.9 OAG07542.1 - 8.1e-11 41.4 3.4 1.2e-10 40.9 3.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.11 OAG07543.1 - 4.8e-153 509.5 0.4 7.7e-153 508.9 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAG07543.1 - 2e-08 33.0 0.2 1.3e-06 27.0 0.0 3.1 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG07543.1 - 2.6e-05 24.2 0.6 6e-05 23.0 0.3 1.7 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAG07543.1 - 0.011 15.1 0.2 0.037 13.4 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF1682 PF07946.14 OAG07543.1 - 0.04 13.1 0.4 0.069 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PEP-utilisers_N PF05524.13 OAG07543.1 - 0.38 10.9 5.2 2.7 8.2 0.0 2.6 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal BAR_3 PF16746.5 OAG07543.1 - 1.8 8.2 4.3 0.32 10.7 0.1 1.8 2 0 0 2 2 2 0 BAR domain of APPL family GFO_IDH_MocA PF01408.22 OAG07546.1 - 1.2e-05 26.2 0.0 2.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SAF PF08666.12 OAG07546.1 - 2.2e-05 25.0 0.0 4.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 SAF domain DapB_N PF01113.20 OAG07546.1 - 7.3e-05 22.9 0.1 0.00024 21.2 0.1 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 OAG07546.1 - 8e-05 23.3 0.1 0.0006 20.5 0.1 2.3 2 1 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 OAG07546.1 - 0.057 13.8 0.1 0.24 11.8 0.0 2.1 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG07546.1 - 0.15 12.3 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain WD40 PF00400.32 OAG07547.1 - 3e-93 303.2 60.0 7.5e-10 39.3 0.8 11.6 9 1 1 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG07547.1 - 1.9e-33 114.6 13.5 0.0019 18.4 0.1 9.8 1 1 9 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG07547.1 - 1.2e-22 80.3 32.4 0.018 13.7 0.4 9.3 1 1 8 9 9 9 9 Nucleoporin Nup120/160 NACHT PF05729.12 OAG07547.1 - 1.3e-21 77.2 0.1 3.3e-21 75.9 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 OAG07547.1 - 5.4e-14 51.9 32.6 0.0017 17.4 0.9 9.0 1 1 6 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein HET PF06985.11 OAG07547.1 - 5.9e-12 46.1 7.6 7.8e-10 39.3 0.1 3.3 2 1 1 3 3 2 2 Heterokaryon incompatibility protein (HET) CDtoxinA PF03498.14 OAG07547.1 - 6.8e-07 29.0 0.1 11 5.6 0.0 5.5 2 2 4 6 6 6 1 Cytolethal distending toxin A/C domain WD40_like PF17005.5 OAG07547.1 - 5.2e-06 26.0 3.1 8 5.7 0.0 5.0 5 0 0 5 5 5 3 WD40-like domain Nbas_N PF15492.6 OAG07547.1 - 0.00017 21.0 31.1 3.4 6.9 0.2 8.9 3 2 7 10 10 10 4 Neuroblastoma-amplified sequence, N terminal cNMP_binding PF00027.29 OAG07547.1 - 0.01 15.9 0.1 19 5.4 0.0 4.4 3 2 2 5 5 5 0 Cyclic nucleotide-binding domain AAA_16 PF13191.6 OAG07547.1 - 0.021 15.2 0.1 0.12 12.7 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 OAG07547.1 - 0.061 13.7 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG07547.1 - 0.13 12.6 0.0 0.38 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CBM_6 PF03422.15 OAG07547.1 - 1.4 9.2 11.8 3.3 8.0 0.3 4.8 2 2 3 5 5 5 0 Carbohydrate binding module (family 6) DUF92 PF01940.16 OAG07550.1 - 0.26 10.7 2.9 0.21 11.0 0.3 1.9 1 1 1 2 2 2 0 Integral membrane protein DUF92 Vut_1 PF02592.15 OAG07550.1 - 2 8.7 13.8 0.5 10.7 1.7 2.5 1 1 2 3 3 3 0 Putative vitamin uptake transporter ECH_1 PF00378.20 OAG07553.1 - 7.3e-27 94.3 0.0 8.2e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG07553.1 - 6.8e-13 48.8 0.0 8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CDH-cyt PF16010.5 OAG07554.1 - 2.8e-46 157.5 4.4 5.6e-46 156.5 4.4 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Lamp PF01299.17 OAG07554.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Pyr_redox_3 PF13738.6 OAG07555.1 - 2.4e-12 46.7 0.0 4.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG07555.1 - 1.6e-11 43.3 0.0 8.7e-11 40.9 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG07555.1 - 4.6e-08 32.7 0.0 3.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG07555.1 - 3e-07 30.6 0.3 1.6e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG07555.1 - 4.4e-07 29.4 0.1 8.2e-05 21.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG07555.1 - 0.00013 21.3 0.0 0.00029 20.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG07555.1 - 0.00034 20.3 0.9 0.022 14.4 0.0 2.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Mqo PF06039.15 OAG07555.1 - 0.0043 15.7 0.0 0.062 11.9 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Shikimate_DH PF01488.20 OAG07555.1 - 0.022 14.8 0.3 0.11 12.6 0.0 2.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAG07555.1 - 0.031 14.2 1.3 8.6 6.3 0.1 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG07555.1 - 0.093 11.8 0.0 1.5 7.8 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG07555.1 - 0.17 11.0 0.0 1.1 8.2 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 OAG07555.1 - 0.47 9.5 1.1 5 6.1 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 OAG07556.1 - 1.8e-29 103.5 0.4 2.3e-29 103.1 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG07556.1 - 0.01 16.0 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG07556.1 - 0.053 13.5 0.3 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG07556.1 - 0.054 12.7 0.0 4 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dioxygenase_C PF00775.21 OAG07558.1 - 6.7e-09 35.4 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Med3 PF11593.8 OAG07558.1 - 0.85 8.7 17.6 1.6 7.8 17.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Coilin_N PF15862.5 OAG07558.1 - 2.4 8.0 6.5 5.3 6.8 6.5 1.6 1 0 0 1 1 1 0 Coilin N-terminus BCS1_N PF08740.11 OAG07559.1 - 2.9e-20 73.0 0.0 4.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAG07559.1 - 3e-15 56.8 0.0 5.4e-13 49.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAG07559.1 - 0.026 15.1 0.0 0.096 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG07559.1 - 0.036 14.5 0.0 0.34 11.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 OAG07559.1 - 0.036 14.2 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAG07559.1 - 0.041 13.6 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAG07559.1 - 0.058 13.4 0.0 0.18 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 OAG07559.1 - 0.12 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OAG07559.1 - 0.13 12.7 0.1 0.51 10.7 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Polyoma_lg_T_C PF06431.11 OAG07559.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_28 PF13521.6 OAG07559.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG07559.1 - 0.22 11.2 0.1 0.43 10.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain adh_short_C2 PF13561.6 OAG07560.1 - 5.1e-40 137.5 0.1 7.8e-40 136.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG07560.1 - 1.1e-36 126.2 0.1 1.7e-36 125.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG07560.1 - 3.5e-11 43.4 0.4 1.1e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 KR domain AlaDh_PNT_C PF01262.21 OAG07560.1 - 0.0037 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG07560.1 - 0.0043 15.8 0.2 0.01 14.6 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein Epimerase PF01370.21 OAG07560.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG07560.1 - 0.055 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 OAG07560.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 OAG07560.1 - 0.073 13.6 0.3 0.25 11.9 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG07560.1 - 1.5 8.7 4.4 1.7 8.5 0.6 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 OAG07562.1 - 5.1e-70 235.8 0.0 1e-69 234.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07562.1 - 1.8e-48 165.1 0.0 3.3e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG07562.1 - 0.00017 20.5 0.0 0.00059 18.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase DUF913 PF06025.12 OAG07562.1 - 0.00029 19.9 1.4 0.017 14.1 0.2 3.2 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) Med15_fungi PF05397.12 OAG07562.1 - 0.0045 17.3 0.5 0.012 15.9 0.5 1.7 1 0 0 1 1 1 1 Mediator complex subunit 15 Kinase-like PF14531.6 OAG07562.1 - 0.0088 15.4 0.0 0.056 12.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pox_Ag35 PF03286.14 OAG07562.1 - 0.11 12.2 1.3 0.28 11.0 1.3 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FTA2 PF13095.6 OAG07562.1 - 0.17 11.5 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4106 PF13388.6 OAG07564.1 - 5.8 6.0 6.8 9.9 5.3 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) HET PF06985.11 OAG07565.1 - 1.4e-24 87.1 0.0 2.4e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HSP20 PF00011.21 OAG07568.1 - 4.5e-17 62.1 0.4 5.5e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG07568.1 - 0.00012 21.6 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA DUF5403 PF17395.2 OAG07568.1 - 0.03 14.6 0.8 0.12 12.6 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5403) PEGA PF08308.11 OAG07568.1 - 0.038 13.9 0.2 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 PEGA domain Ndc1_Nup PF09531.10 OAG07568.1 - 3.9 6.0 8.9 6 5.4 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Oxidored_q6 PF01058.22 OAG07570.1 - 5.1e-22 78.1 0.1 7.4e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sedlin_N PF04628.13 OAG07571.1 - 4.7e-15 55.9 0.0 1.2e-14 54.6 0.0 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OAG07571.1 - 0.07 13.0 0.1 1.8 8.5 0.1 2.2 1 1 0 1 1 1 0 Sybindin-like family AFG1_ATPase PF03969.16 OAG07572.1 - 5.8e-56 189.9 0.0 2.6e-27 95.6 0.0 5.1 4 1 0 5 5 5 4 AFG1-like ATPase AAA_5 PF07728.14 OAG07572.1 - 2.5e-06 27.5 0.0 5.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG07572.1 - 6e-06 26.7 0.1 0.00041 20.8 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG07572.1 - 0.0016 18.7 0.0 0.0039 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAG07572.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAG07572.1 - 0.024 14.4 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OAG07572.1 - 0.075 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 OAG07572.1 - 0.091 13.3 0.1 6.3 7.3 0.0 2.5 1 1 0 2 2 2 0 ABC transporter TsaE PF02367.17 OAG07572.1 - 0.16 11.9 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 OAG07572.1 - 0.21 11.3 0.0 0.61 9.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain OTCace PF00185.24 OAG07573.1 - 1.9e-44 151.5 0.0 2.5e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 OAG07573.1 - 6.4e-43 146.3 0.0 9.4e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3712 PF12505.8 OAG07574.1 - 9.5e-10 38.8 0.3 3.1e-06 27.5 0.5 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAG07574.1 - 1.7e-05 25.3 2.2 0.62 10.6 0.0 4.6 5 0 0 5 5 5 2 Late embryogenesis abundant protein DUF1356 PF07092.12 OAG07574.1 - 0.0057 16.0 2.2 0.0097 15.2 1.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1356) DSPc PF00782.20 OAG07575.1 - 3.3e-27 94.9 0.0 4.9e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Yippee-Mis18 PF03226.14 OAG07575.1 - 0.025 14.8 2.3 0.22 11.7 2.3 2.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Y_phosphatase PF00102.27 OAG07575.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OAG07575.1 - 0.06 13.3 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OAG07575.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF5000 PF16391.5 OAG07575.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function zinc_ribbon_4 PF13717.6 OAG07575.1 - 0.26 11.3 2.8 11 6.1 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 OAG07576.1 - 0.0094 16.4 19.2 0.1 13.1 1.3 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG07576.1 - 2.1 9.4 22.3 1.2 10.1 1.7 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger Vfa1 PF08432.10 OAG07577.1 - 1.9e-57 194.5 15.3 2.2e-57 194.3 15.3 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 BORG_CEP PF14957.6 OAG07577.1 - 0.0066 17.6 1.6 0.0093 17.1 1.6 1.2 1 0 0 1 1 1 1 Cdc42 effector DUF2347 PF09804.9 OAG07577.1 - 0.026 14.1 1.2 0.034 13.7 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4775 PF16001.5 OAG07577.1 - 0.075 12.4 20.9 0.085 12.3 20.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Dapper PF15268.6 OAG07577.1 - 0.088 11.7 9.9 0.1 11.4 9.9 1.0 1 0 0 1 1 1 0 Dapper DDHD PF02862.17 OAG07577.1 - 0.17 12.0 4.1 0.2 11.8 4.1 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 OAG07577.1 - 0.23 11.3 19.3 0.37 10.6 19.3 1.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 OAG07577.1 - 0.3 10.0 2.6 0.32 9.9 2.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 OAG07577.1 - 0.48 9.4 8.4 0.53 9.2 8.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 U79_P34 PF03064.16 OAG07577.1 - 0.51 9.7 16.9 0.73 9.1 16.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ycf1 PF05758.12 OAG07577.1 - 0.52 8.1 11.2 0.58 8.0 11.2 1.0 1 0 0 1 1 1 0 Ycf1 PPL5 PF18168.1 OAG07577.1 - 0.76 9.0 9.0 0.94 8.7 9.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 TP53IP5 PF15331.6 OAG07577.1 - 1.1 9.4 10.8 1.5 8.9 10.8 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 OAG07577.1 - 2.1 7.0 10.1 2.6 6.7 10.1 1.1 1 0 0 1 1 1 0 Presenilin GNAT_acetyltr_2 PF13718.6 OAG07577.1 - 2.2 7.6 6.6 2.9 7.2 6.6 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 AAA_11 PF13086.6 OAG07577.1 - 2.4 7.9 10.3 3 7.6 10.3 1.3 1 0 0 1 1 1 0 AAA domain VIR_N PF15912.5 OAG07577.1 - 3.3 7.3 9.7 4.6 6.8 9.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Zip PF02535.22 OAG07577.1 - 3.5 6.7 4.9 4 6.5 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Atrophin-1 PF03154.15 OAG07577.1 - 4.3 5.5 19.4 5.9 5.1 19.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family NPR3 PF03666.13 OAG07577.1 - 5.8 5.6 13.9 6.3 5.5 13.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 OAG07577.1 - 6 6.8 4.8 7.5 6.5 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRN3 PF05327.11 OAG07577.1 - 7.3 5.0 13.2 8.2 4.8 13.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATP11 PF06644.11 OAG07577.1 - 7.9 6.2 14.3 10 5.8 14.3 1.2 1 0 0 1 1 1 0 ATP11 protein FAM60A PF15396.6 OAG07577.1 - 8.5 6.3 15.1 4 7.4 12.3 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Paramyxo_ncap PF00973.19 OAG07577.1 - 8.6 5.1 8.3 10 4.9 8.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TatD_DNase PF01026.21 OAG07578.1 - 3.8e-48 164.1 0.0 4.5e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF4777 PF16007.5 OAG07578.1 - 0.087 13.1 0.0 0.3 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Copper-bind PF00127.20 OAG07579.1 - 0.00017 22.0 0.1 0.00032 21.1 0.1 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Abhydrolase_1 PF00561.20 OAG07580.1 - 7.8e-09 35.5 0.2 4.8e-08 32.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG07580.1 - 5.1e-07 30.5 0.8 7e-07 30.1 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG07580.1 - 0.05 13.7 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein FGase PF05013.12 OAG07580.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Astacin PF01400.24 OAG07581.1 - 1.3e-09 38.0 0.7 2.9e-08 33.6 0.2 2.4 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 OAG07581.1 - 0.0015 18.2 0.0 0.008 15.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAG07581.1 - 0.0099 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OAG07581.1 - 0.016 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Matrixin HycA_repressor PF11046.8 OAG07581.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons SNURF PF07192.11 OAG07581.1 - 1.1 9.2 3.6 2.5 8.0 1.3 2.4 3 0 0 3 3 3 0 SNURF/RPN4 protein PPR_2 PF13041.6 OAG07582.1 - 3.3e-36 123.2 0.3 1.2e-16 60.6 0.0 4.7 4 1 1 5 5 5 3 PPR repeat family PPR_1 PF12854.7 OAG07582.1 - 2.7e-19 68.5 0.0 7.2e-05 22.4 0.0 5.8 6 0 0 6 6 6 5 PPR repeat PPR_3 PF13812.6 OAG07582.1 - 8.5e-19 67.4 0.1 1.1e-08 35.0 0.0 3.4 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 OAG07582.1 - 3.3e-15 55.2 4.1 4.3e-05 23.5 0.0 7.2 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.4 OAG07582.1 - 1.3e-08 34.5 0.0 0.00013 21.5 0.0 2.6 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OAG07582.1 - 0.0054 17.4 0.5 3.1 8.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat MRP-S27 PF10037.9 OAG07582.1 - 0.071 12.0 2.6 3.3 6.5 0.0 3.2 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 OAG07582.1 - 0.11 13.0 0.0 0.69 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat cwf18 PF08315.12 OAG07583.1 - 1.7e-39 135.6 7.3 1.7e-39 135.6 7.3 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.6 OAG07584.1 - 4.8e-16 58.4 4.2 4.8e-16 58.4 4.2 3.0 4 0 0 4 4 4 1 Zinc knuckle zf-CCHC PF00098.23 OAG07584.1 - 0.019 15.0 1.1 0.032 14.3 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle SUZ PF12752.7 OAG07585.1 - 7.1e-15 55.5 3.7 7.1e-15 55.5 3.7 3.9 5 0 0 5 5 5 1 SUZ domain R3H PF01424.22 OAG07585.1 - 7.9e-07 29.0 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain AA_permease_2 PF13520.6 OAG07586.1 - 1.4e-54 185.6 60.7 1.8e-54 185.2 60.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG07586.1 - 4e-25 88.4 51.5 5.2e-25 88.0 51.5 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 OAG07588.1 - 7.1e-09 35.9 0.0 3e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG07588.1 - 1.6e-05 25.2 0.0 4.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG07588.1 - 0.00086 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG07588.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG07588.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 OAG07588.1 - 0.15 12.1 0.0 15 5.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CFEM PF05730.11 OAG07589.1 - 7.1e-06 26.0 10.9 7.1e-06 26.0 10.9 2.7 3 0 0 3 3 3 1 CFEM domain Sigma_reg_N PF13800.6 OAG07589.1 - 9.9 6.5 7.6 28 5.1 0.1 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal p450 PF00067.22 OAG07590.1 - 2.2e-62 211.3 0.0 2.8e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 OAG07591.1 - 4.1e-09 37.2 0.0 5.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG07591.1 - 1.6e-06 28.4 0.0 5.5e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain COMP PF11598.8 OAG07591.1 - 1.2 9.7 3.3 0.46 11.0 0.4 1.9 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Fungal_trans PF04082.18 OAG07592.1 - 4.3e-09 35.8 0.2 7.3e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07592.1 - 1.5e-05 25.0 10.0 2.4e-05 24.4 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALG11_N PF15924.5 OAG07593.1 - 1.2e-83 280.3 0.0 1.6e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OAG07593.1 - 1.2e-19 70.5 0.0 4.7e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG07593.1 - 6.2e-10 39.6 0.0 2e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG07593.1 - 0.021 14.8 0.3 0.043 13.8 0.3 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 60KD_IMP PF02096.20 OAG07594.1 - 4.2e-09 36.5 0.0 5.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein MID_MedPIWI PF18296.1 OAG07595.1 - 0.006 16.4 1.5 0.007 16.2 1.5 1.1 1 0 0 1 1 1 1 MID domain of medPIWI MSP1_C PF07462.11 OAG07595.1 - 0.55 8.9 5.4 0.68 8.6 5.4 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1373 PF07117.11 OAG07595.1 - 1.3 9.0 10.9 1.6 8.7 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) DENN PF02141.21 OAG07596.1 - 2.2e-56 190.8 0.1 3.9e-56 190.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OAG07596.1 - 1.9e-15 57.4 0.0 5.8e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OAG07596.1 - 5.2e-15 55.2 1.3 1.3e-14 53.9 1.3 1.7 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 OAG07596.1 - 9.2e-05 22.7 5.6 0.00018 21.8 5.6 1.5 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 OAG07596.1 - 0.0099 15.8 6.7 0.019 14.9 6.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 OAG07596.1 - 0.093 12.6 3.3 0.18 11.7 3.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-HIT PF04438.16 OAG07596.1 - 0.89 9.5 3.8 1.7 8.6 3.8 1.4 1 0 0 1 1 1 0 HIT zinc finger CENP-K PF11802.8 OAG07596.1 - 1.1 8.8 4.7 0.38 10.3 0.8 1.9 2 0 0 2 2 2 0 Centromere-associated protein K DUF974 PF06159.13 OAG07598.1 - 1.8e-73 247.4 0.0 2.2e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) SET PF00856.28 OAG07599.1 - 1.7e-14 54.6 0.0 4.7e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF2408 PF10303.9 OAG07600.1 - 4.1e-44 150.4 7.6 1e-26 94.1 0.9 5.5 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) DUF2920 PF11144.8 OAG07600.1 - 0.028 13.6 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) AATF-Che1 PF13339.6 OAG07600.1 - 0.12 13.0 2.4 1.2 9.8 0.6 3.2 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Ribosomal_60s PF00428.19 OAG07601.1 - 3.8e-26 91.5 9.5 4.6e-26 91.2 9.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Aldo_ket_red PF00248.21 OAG07602.1 - 1.7e-77 260.5 0.0 1.9e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flavoprotein PF02441.19 OAG07603.1 - 3.3e-45 153.7 0.0 7.5e-45 152.5 0.0 1.5 1 1 0 1 1 1 1 Flavoprotein DUF1749 PF08538.10 OAG07604.1 - 1.4e-75 254.2 0.0 1.6e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OAG07604.1 - 0.0018 18.9 0.0 0.0022 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG07604.1 - 0.0025 17.1 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 RsbRD_N PF14361.6 OAG07604.1 - 0.15 12.8 0.0 0.48 11.1 0.0 1.9 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Abhydrolase_1 PF00561.20 OAG07604.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S41 PF03572.18 OAG07605.1 - 1.2e-07 31.4 0.0 3.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 Stealth_CR4 PF17103.5 OAG07605.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 AIM5 PF17050.5 OAG07606.1 - 1.4e-13 51.4 0.1 2.2e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DUF4816 PF16086.5 OAG07606.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4816) FAM25 PF15825.5 OAG07606.1 - 0.13 12.6 0.0 1.8 9.0 0.0 2.1 2 0 0 2 2 2 0 FAM25 family AhpC-TSA PF00578.21 OAG07609.1 - 1.7e-23 82.9 0.0 2.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG07609.1 - 2.4e-16 59.8 0.0 4.6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 OAG07609.1 - 0.033 14.3 0.0 0.097 12.8 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme TRM13 PF05206.14 OAG07610.1 - 0.19 11.2 0.8 0.22 11.0 0.8 1.0 1 0 0 1 1 1 0 Methyltransferase TRM13 NCBP3 PF10309.9 OAG07611.1 - 1.8e-08 34.1 0.0 3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 adh_short_C2 PF13561.6 OAG07612.1 - 2.4e-62 210.6 0.7 3.1e-62 210.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG07612.1 - 4.4e-51 173.1 1.5 5.8e-51 172.7 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG07612.1 - 4.8e-08 33.1 0.4 7e-08 32.6 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG07612.1 - 0.00077 19.0 0.3 0.0014 18.1 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG07612.1 - 0.0053 16.7 0.3 0.0078 16.1 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG07612.1 - 0.012 14.6 0.3 0.019 14.0 0.3 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.21 OAG07612.1 - 0.033 14.2 0.3 0.055 13.5 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aldedh PF00171.22 OAG07613.1 - 1.3e-154 515.2 0.1 1.6e-154 514.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 OAG07615.1 - 8.3e-57 192.4 0.0 1e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG07615.1 - 7e-45 152.9 0.0 9.3e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG07615.1 - 2.8e-08 33.9 0.0 4.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG07615.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 OAG07615.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DPBB_1 PF03330.18 OAG07617.1 - 0.033 14.4 0.1 0.079 13.2 0.1 1.6 1 0 0 1 1 1 0 Lytic transglycolase Neisseria_TspB PF05616.13 OAG07617.1 - 0.15 10.5 9.7 0.18 10.3 9.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein YTH PF04146.15 OAG07618.1 - 0.029 14.3 1.0 0.031 14.2 1.0 1.3 1 1 0 1 1 1 0 YT521-B-like domain SOG2 PF10428.9 OAG07618.1 - 1 8.5 18.9 1.2 8.2 18.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.22 OAG07618.1 - 2.4 7.3 6.4 2.6 7.2 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3328 PF11807.8 OAG07619.1 - 1.5e-36 126.3 0.0 1.8e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PepSY_2 PF13670.6 OAG07620.1 - 0.044 13.8 1.6 0.59 10.2 0.9 2.2 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain Gpi1 PF05024.15 OAG07620.1 - 0.13 12.3 1.1 1.5e+02 2.3 0.0 3.8 2 1 2 4 4 4 0 N-acetylglucosaminyl transferase component (Gpi1) S36_mt PF10937.8 OAG07623.1 - 1.7e-41 142.4 1.9 1.9e-41 142.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial zf-TFIIIC PF12660.7 OAG07624.1 - 0.076 13.0 3.1 0.12 12.3 3.1 1.6 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Med18 PF09637.10 OAG07625.1 - 3.4e-50 171.2 0.0 3.9e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.11 OAG07626.1 - 1.7e-58 196.9 0.0 2.9e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OAG07626.1 - 5.5e-25 88.2 0.0 2.8e-22 79.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAG07626.1 - 0.012 15.1 0.4 0.5 9.8 0.0 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Fungal_trans PF04082.18 OAG07630.1 - 2.8e-28 98.7 0.1 4.2e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07630.1 - 1.5e-07 31.4 8.8 3.2e-07 30.3 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chorismate_synt PF01264.21 OAG07631.1 - 5.2e-138 459.2 0.0 6e-138 459.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase CRAL_TRIO_2 PF13716.6 OAG07632.1 - 8.8e-35 119.9 0.0 1.4e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 OAG07632.1 - 3.4e-20 72.4 0.0 7.1e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 OAG07632.1 - 9.8e-06 25.4 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Tcp11 PF05794.13 OAG07633.1 - 2.3e-107 359.8 0.3 2.3e-107 359.8 0.3 2.9 3 0 0 3 3 3 1 T-complex protein 11 UPF0242 PF06785.11 OAG07633.1 - 0.12 12.5 6.6 0.3 11.2 6.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3824 PF12868.7 OAG07633.1 - 0.54 10.9 12.7 1.9 9.2 12.7 2.0 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SCAMP PF04144.13 OAG07634.1 - 0.011 16.0 1.6 0.022 15.1 1.6 1.4 1 0 0 1 1 1 0 SCAMP family Dabb PF07876.12 OAG07635.1 - 2.1e-25 89.2 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1761 PF08570.10 OAG07636.1 - 7.8e-28 97.2 3.0 8.9e-28 97.1 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) QCR10 PF09796.9 OAG07636.1 - 2.2 8.4 5.4 1.7 8.8 0.3 3.0 2 2 2 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RIX1 PF08167.12 OAG07637.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.4 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis AAA_22 PF13401.6 OAG07638.1 - 7e-05 23.1 0.1 0.00031 21.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG07638.1 - 0.0011 19.4 1.1 0.0035 17.7 0.1 2.3 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 OAG07638.1 - 0.0019 18.2 0.0 0.013 15.4 0.0 2.5 1 1 0 1 1 1 1 NACHT domain DUF760 PF05542.11 OAG07638.1 - 0.043 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF760) NIF PF03031.18 OAG07639.1 - 6e-58 195.0 0.0 8.5e-58 194.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SMBP PF16785.5 OAG07639.1 - 0.16 12.2 0.9 0.32 11.2 0.4 1.7 2 0 0 2 2 2 0 Small metal-binding protein IF-2B PF01008.17 OAG07640.1 - 1e-58 198.8 2.3 1.4e-34 119.6 0.0 2.9 2 1 0 2 2 2 2 Initiation factor 2 subunit family EamA PF00892.20 OAG07641.1 - 6.9e-20 71.6 30.4 1.4e-10 41.4 14.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 OAG07641.1 - 3.8 5.7 15.5 0.32 9.2 10.4 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) RseC_MucC PF04246.12 OAG07641.1 - 4.5 7.2 6.6 20 5.1 0.0 3.6 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC HET PF06985.11 OAG07642.1 - 3.8e-25 89.0 0.0 6.5e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG07643.1 - 9.5e-10 39.0 11.3 2.3e-08 34.5 3.7 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG07645.1 - 1.2e-22 80.3 63.6 1.6e-22 79.9 46.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OAG07645.1 - 0.00031 19.3 4.8 0.00031 19.3 4.8 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector DUF2238 PF09997.9 OAG07645.1 - 0.13 12.1 5.3 0.84 9.4 0.3 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) G-patch PF01585.23 OAG07646.1 - 2.6e-12 46.4 0.2 5.4e-12 45.4 0.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAG07646.1 - 0.0041 17.2 0.4 0.0041 17.2 0.4 1.9 2 0 0 2 2 2 1 G-patch domain Nup35_RRM_2 PF14605.6 OAG07646.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AMP-binding PF00501.28 OAG07647.1 - 3e-87 293.0 0.0 3.5e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG07647.1 - 4e-14 53.4 0.4 2.3e-13 50.9 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 OAG07647.1 - 7.2e-05 21.8 0.0 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 OAG07647.1 - 0.0043 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 RTX C-terminal domain PSCyt1 PF07635.11 OAG07647.1 - 0.21 12.2 0.0 9.7 6.9 0.0 2.9 2 0 0 2 2 2 0 Planctomycete cytochrome C Tautomerase_3 PF14832.6 OAG07649.1 - 1.9e-55 186.8 0.0 2.2e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 OAG07649.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Tautomerase enzyme NmrA PF05368.13 OAG07650.1 - 3.2e-14 53.1 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG07650.1 - 1.9e-10 40.9 0.0 2.9e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG07650.1 - 0.00038 20.9 0.0 0.00079 19.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG07650.1 - 0.0025 17.3 0.0 0.0076 15.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 OAG07650.1 - 0.047 14.5 0.0 0.094 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PBP3 PF18056.1 OAG07653.1 - 0.089 12.9 0.6 15 5.8 0.0 3.5 4 0 0 4 4 4 0 Penicillin Binding Protein 3 Domain DUF3899 PF13038.6 OAG07654.1 - 0.015 15.7 0.1 0.26 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF1689 PF07954.11 OAG07654.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) DEK_C PF08766.11 OAG07654.1 - 0.18 11.7 0.1 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 DEK C terminal domain ATPase_gene1 PF09527.10 OAG07654.1 - 6 7.1 8.5 2 8.6 0.6 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF4286 PF14114.6 OAG07655.1 - 0.053 14.0 0.0 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Tcp11 PF05794.13 OAG07656.1 - 1.9e-96 323.8 0.3 2.4e-96 323.5 0.3 1.0 1 0 0 1 1 1 1 T-complex protein 11 CTP_transf_like PF01467.26 OAG07657.1 - 2.4e-28 99.1 0.0 6.6e-28 97.7 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like WD40 PF00400.32 OAG07658.1 - 1.1e-30 105.2 14.9 4.8e-08 33.5 0.2 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG07658.1 - 1.1e-14 54.4 1.7 0.0059 16.9 0.1 4.8 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 OAG07658.1 - 0.051 11.6 1.9 0.5 8.3 0.3 2.4 3 0 0 3 3 3 0 IKI3 family eIF2A PF08662.11 OAG07658.1 - 0.14 12.0 0.2 17 5.3 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OAG07658.1 - 0.15 11.1 0.8 0.26 10.3 0.1 1.7 2 0 0 2 2 2 0 Coatomer WD associated region MHYT PF03707.16 OAG07659.1 - 6.3e-17 61.5 10.1 1.9e-08 34.4 0.1 4.2 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Saf_2TM PF18303.1 OAG07659.1 - 0.035 13.7 0.7 6.8 6.3 0.0 2.7 1 1 2 3 3 3 0 SAVED-fused 2TM effector domain Bestrophin PF01062.21 OAG07659.1 - 0.042 13.2 0.7 0.12 11.8 0.1 2.1 3 0 0 3 3 3 0 Bestrophin, RFP-TM, chloride channel GspL_C PF12693.7 OAG07659.1 - 0.066 13.0 1.4 0.59 10.0 0.0 2.8 3 0 0 3 3 3 0 GspL periplasmic domain DUF1345 PF07077.11 OAG07659.1 - 0.14 11.9 1.6 0.77 9.4 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF2157 PF09925.9 OAG07659.1 - 0.14 11.9 11.9 0.031 14.0 5.0 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) PPDFL PF15060.6 OAG07659.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 Differentiation and proliferation regulator CitMHS PF03600.16 OAG07659.1 - 0.17 11.0 2.7 2.2 7.4 2.8 2.1 1 1 0 1 1 1 0 Citrate transporter DUF1129 PF06570.11 OAG07659.1 - 0.6 9.6 2.1 3.1 7.2 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ABC2_membrane_5 PF13346.6 OAG07659.1 - 0.92 9.0 9.7 0.042 13.4 2.3 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4131 PF13567.6 OAG07659.1 - 5.4 6.6 18.5 0.3 10.7 5.6 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF5346 PF17281.2 OAG07663.1 - 0.027 14.5 0.3 0.064 13.3 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5346) IQ PF00612.27 OAG07663.1 - 9.1 6.4 6.7 25 5.0 0.4 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif ALAD PF00490.21 OAG07664.1 - 2.5e-119 398.1 0.0 2.9e-119 397.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase RecR PF02132.15 OAG07668.1 - 5.9 6.5 8.5 0.35 10.5 0.4 2.4 2 0 0 2 2 2 0 RecR protein GMC_oxred_C PF05199.13 OAG07669.1 - 2.8e-12 47.4 0.0 3.3e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase PCI PF01399.27 OAG07669.1 - 0.027 15.0 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 PCI domain DUF1996 PF09362.10 OAG07670.1 - 4.8e-80 268.9 3.8 5.9e-80 268.6 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.11 OAG07673.1 - 3.1e-11 43.8 7.4 8.8e-09 35.9 2.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ribosomal_L3 PF00297.22 OAG07674.1 - 3e-17 62.7 4.2 2.4e-13 49.8 1.3 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Hexapep_2 PF14602.6 OAG07675.1 - 5.5e-13 48.4 10.1 5.6e-08 32.4 0.7 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 OAG07675.1 - 4.8e-12 45.1 13.2 4.2e-08 32.6 2.2 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 OAG07675.1 - 1.8e-09 37.7 0.0 3.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 OAG07675.1 - 8.4e-09 35.4 9.3 1.6e-08 34.5 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VLPT PF07122.11 OAG07675.1 - 0.18 11.5 1.9 0.46 10.3 1.9 1.6 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) DUF202 PF02656.15 OAG07679.1 - 1.3e-13 51.1 2.8 1.3e-13 51.1 2.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5134 PF17197.4 OAG07679.1 - 0.0042 17.0 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5134) DUF5337 PF17272.2 OAG07679.1 - 1.3 8.9 9.4 0.22 11.3 5.2 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5337) Tctex-1 PF03645.13 OAG07680.1 - 4.1e-32 110.5 0.0 4.7e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Meth_synt_2 PF01717.18 OAG07681.1 - 5.2e-156 518.9 0.0 6.2e-149 495.6 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG07681.1 - 2.5e-124 414.9 0.0 2.1e-117 392.1 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 OAG07681.1 - 0.00048 19.4 0.0 0.22 10.6 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 OAG07681.1 - 0.94 9.3 4.4 0.28 11.0 0.3 2.3 2 0 0 2 2 2 0 Short C-terminal domain adh_short PF00106.25 OAG07682.1 - 2.6e-43 147.8 0.5 4.9e-43 146.9 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07682.1 - 2.2e-38 132.2 0.2 4.7e-38 131.0 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07682.1 - 4.1e-14 52.9 0.1 7.4e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG07682.1 - 3.1e-05 23.5 0.3 8.7e-05 22.1 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Kelch_5 PF13854.6 OAG07682.1 - 0.001 19.0 1.9 0.042 13.9 0.0 3.0 3 0 0 3 3 3 1 Kelch motif DUF1776 PF08643.10 OAG07682.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Kelch_4 PF13418.6 OAG07682.1 - 0.11 12.6 1.9 0.49 10.5 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain CorA PF01544.18 OAG07684.1 - 0.00068 19.0 5.2 0.00068 19.0 5.2 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Laminin_I PF06008.14 OAG07684.1 - 0.063 13.0 3.3 0.12 12.1 3.3 1.3 1 0 0 1 1 1 0 Laminin Domain I YebO PF13974.6 OAG07684.1 - 0.16 12.1 6.0 0.063 13.4 1.7 2.4 1 1 1 2 2 2 0 YebO-like protein Pkinase PF00069.25 OAG07685.1 - 2.9e-20 72.8 0.0 1.3e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07685.1 - 5.7e-07 29.1 0.0 1e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Glutaredoxin PF00462.24 OAG07686.1 - 7.3e-15 54.9 0.0 1.3e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin PBP_dimer PF03717.15 OAG07687.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain Alg14 PF08660.11 OAG07688.1 - 1.1e-49 168.7 0.0 1.5e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like KOW PF00467.29 OAG07689.1 - 0.001 18.9 4.8 0.0012 18.7 3.0 2.1 2 0 0 2 2 2 1 KOW motif VIT PF08487.10 OAG07689.1 - 2.7 8.2 5.4 5.8 7.2 0.3 2.4 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Ima1_N PF09779.9 OAG07690.1 - 1.5e-32 113.3 1.0 7.1e-32 111.1 1.5 1.9 2 0 0 2 2 2 1 Ima1 N-terminal domain RNHCP PF12647.7 OAG07690.1 - 0.0061 16.5 0.4 0.0061 16.5 0.4 1.7 2 0 0 2 2 2 1 RNHCP domain Vps36-NZF-N PF16988.5 OAG07690.1 - 0.019 14.4 0.2 0.29 10.5 0.0 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Mob_synth_C PF06463.13 OAG07690.1 - 0.071 13.0 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C DZR PF12773.7 OAG07690.1 - 0.094 12.8 3.9 6.5 6.9 0.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 OAG07690.1 - 1.4 8.9 4.2 0.42 10.6 1.1 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PriA_CRR PF18319.1 OAG07690.1 - 2.2 8.3 5.1 0.68 10.0 0.8 2.5 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Ribosom_S12_S23 PF00164.25 OAG07691.1 - 6.4e-51 170.8 0.7 8e-51 170.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 OAG07692.1 - 4.2e-22 77.8 3.5 4.2e-22 77.8 3.5 1.8 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Carbpep_Y_N PF05388.11 OAG07692.1 - 0.088 13.4 2.3 2.9 8.5 1.0 2.3 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Nucleo_P87 PF07267.11 OAG07692.1 - 0.27 10.0 4.3 0.35 9.7 4.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mobilization_B PF17511.2 OAG07692.1 - 0.32 11.4 0.1 0.32 11.4 0.1 2.5 2 1 0 2 2 2 0 Mobilization protein B Microtub_bind PF13931.6 OAG07692.1 - 9.8 6.6 9.2 22 5.4 5.4 2.8 2 1 1 3 3 3 0 Kinesin-associated microtubule-binding MFS_1 PF07690.16 OAG07693.1 - 1.4e-36 126.1 26.5 2.4e-36 125.4 26.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_A8 PF01252.18 OAG07693.1 - 0.32 11.2 6.2 5.3 7.3 0.8 2.9 2 0 0 2 2 2 0 Signal peptidase (SPase) II RNHCP PF12647.7 OAG07694.1 - 2.2 8.3 6.3 0.52 10.3 1.7 2.3 3 0 0 3 3 3 0 RNHCP domain peroxidase PF00141.23 OAG07695.1 - 2e-48 165.1 0.0 3.2e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Tannase PF07519.11 OAG07696.1 - 2.8e-100 336.5 0.8 3.3e-100 336.2 0.8 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG07696.1 - 0.0053 16.3 0.6 0.043 13.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family PNGaseA PF12222.8 OAG07697.1 - 1.5e-170 567.8 5.6 1.9e-170 567.4 5.6 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.13 OAG07699.1 - 9.7e-24 83.8 0.0 1.5e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF1485 PF07364.12 OAG07699.1 - 0.045 13.0 0.0 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Metallopeptidase family M81 CorA PF01544.18 OAG07700.1 - 2.5e-13 50.0 0.6 2.4e-12 46.8 0.0 2.1 1 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Virul_fac_BrkB PF03631.15 OAG07700.1 - 0.0042 16.7 0.6 0.0064 16.1 0.6 1.2 1 0 0 1 1 1 1 Virulence factor BrkB PMP22_Claudin PF00822.20 OAG07700.1 - 0.039 13.8 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family ERGIC_N PF13850.6 OAG07700.1 - 0.047 14.0 2.4 0.1 13.0 0.2 2.6 2 1 1 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HisKA PF00512.25 OAG07700.1 - 0.89 9.6 6.3 2.6 8.1 1.5 3.8 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain SPC12 PF06645.13 OAG07700.1 - 1.9 8.7 4.8 21 5.3 0.4 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GMC_oxred_N PF00732.19 OAG07701.1 - 5.1e-66 223.0 0.0 6.9e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG07701.1 - 4.9e-37 127.6 0.0 9.4e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG07701.1 - 8.2e-08 32.2 0.7 2.4e-07 30.7 0.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG07701.1 - 0.00032 20.0 0.3 0.19 11.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG07701.1 - 0.00033 20.0 1.7 0.0004 19.7 0.0 1.9 2 1 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OAG07701.1 - 0.00037 20.7 0.1 0.00088 19.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG07701.1 - 0.0022 17.2 0.3 0.079 12.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAG07701.1 - 0.0026 16.9 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG07701.1 - 0.007 15.6 0.8 0.069 12.4 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG07701.1 - 0.049 12.3 0.4 0.27 9.9 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 OAG07701.1 - 0.063 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain PRELI PF04707.14 OAG07702.1 - 8.5e-44 149.1 0.1 1e-43 148.9 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family OprB PF04966.12 OAG07702.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family DJ-1_PfpI PF01965.24 OAG07703.1 - 4.1e-08 33.2 0.0 5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HMA PF00403.26 OAG07704.1 - 1.2e-15 57.7 0.9 1.4e-15 57.4 0.9 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.14 OAG07704.1 - 0.051 13.7 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Fer2_BFD PF04324.15 OAG07704.1 - 0.091 13.1 0.2 0.27 11.6 0.1 1.8 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain BRO1 PF03097.18 OAG07705.1 - 1.6e-126 422.3 1.2 1.9e-125 418.7 0.0 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAG07705.1 - 4.9e-82 275.6 4.6 4.9e-82 275.6 4.6 2.4 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV SpoU_sub_bind PF08032.12 OAG07705.1 - 0.091 13.1 1.8 5.2 7.4 0.0 3.1 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding zf-C2H2 PF00096.26 OAG07706.1 - 8.6e-13 48.0 12.6 2.7e-06 27.5 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG07706.1 - 1.8e-11 43.9 10.7 5.5e-08 32.9 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG07706.1 - 4.8e-09 36.3 10.6 0.0003 21.4 1.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG07706.1 - 1.1e-08 34.8 5.8 0.00024 21.0 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG07706.1 - 2.7e-06 27.5 0.4 0.066 13.5 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG07706.1 - 1.4e-05 25.3 0.9 0.0099 16.2 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OAG07706.1 - 0.01 15.6 5.4 0.31 10.8 0.7 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 OAG07706.1 - 0.014 15.9 1.2 0.014 15.9 1.2 1.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 OAG07706.1 - 0.033 14.5 1.4 0.064 13.6 1.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 OAG07706.1 - 0.25 11.6 2.7 11 6.3 0.1 2.4 1 1 0 2 2 2 0 LIM domain zf-C2HE PF16278.5 OAG07706.1 - 0.59 10.6 2.0 5.4 7.6 0.3 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C5HCH PF17982.1 OAG07706.1 - 4.5 7.5 6.1 12 6.1 1.5 2.4 1 1 1 2 2 2 0 NSD Cys-His rich domain DUF4360 PF14273.6 OAG07708.1 - 2.4e-61 206.7 1.4 1.4e-60 204.2 1.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Sugar_tr PF00083.24 OAG07709.1 - 1e-44 153.2 14.4 1.9e-44 152.3 14.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07709.1 - 9e-18 64.3 22.4 9e-18 64.3 22.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Cutinase PF01083.22 OAG07710.1 - 1.1e-27 97.1 0.2 1.8e-27 96.4 0.2 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG07710.1 - 0.00056 19.5 0.1 0.00085 18.9 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 OAG07710.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PA_decarbox PF05870.11 OAG07711.1 - 3.4e-10 39.8 0.2 4.6e-10 39.4 0.2 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Vif PF00559.17 OAG07711.1 - 0.00065 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral Vif (Viral infectivity) protein NOA36 PF06524.12 OAG07713.1 - 3.7e-05 23.2 21.1 7e-05 22.3 21.1 1.5 1 0 0 1 1 1 1 NOA36 protein BUD22 PF09073.10 OAG07713.1 - 0.0015 17.9 25.6 0.0022 17.4 25.6 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 OAG07713.1 - 0.0028 16.0 24.6 0.0036 15.6 24.6 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 OAG07713.1 - 0.011 14.0 15.9 0.014 13.7 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAG07713.1 - 0.014 13.5 30.3 0.02 13.0 30.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi SGT1 PF07093.11 OAG07713.1 - 0.095 11.1 6.9 0.1 11.0 6.9 1.1 1 0 0 1 1 1 0 SGT1 protein RNA_pol_3_Rpc31 PF11705.8 OAG07713.1 - 0.15 12.3 33.4 0.047 13.9 23.5 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Apt1 PF10351.9 OAG07713.1 - 0.18 10.6 4.0 0.22 10.4 4.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sigma70_ner PF04546.13 OAG07713.1 - 0.18 11.7 17.0 0.44 10.4 16.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Osteopontin PF00865.18 OAG07713.1 - 0.19 11.2 22.3 0.26 10.7 22.3 1.2 1 0 0 1 1 1 0 Osteopontin Astro_capsid_p PF12226.8 OAG07713.1 - 0.24 10.5 16.0 0.4 9.8 16.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 OAG07713.1 - 0.78 9.3 21.7 0.064 12.8 17.0 1.6 2 0 0 2 2 2 0 PPP4R2 CobT PF06213.12 OAG07713.1 - 6.8 6.0 21.4 11 5.3 21.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 OAG07713.1 - 8.5 5.0 10.1 10 4.8 10.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rhabdo_ncap PF00945.18 OAG07713.1 - 9.3 5.0 9.1 14 4.4 9.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF4637 PF15470.6 OAG07713.1 - 9.5 5.9 15.6 19 4.9 15.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) F-box-like PF12937.7 OAG07715.1 - 1.7e-05 24.6 0.1 5.6e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG07715.1 - 1.8e-05 24.5 0.1 0.0035 17.2 0.0 2.8 2 0 0 2 2 2 2 F-box domain PsbI PF02532.14 OAG07715.1 - 0.0056 16.6 0.9 0.014 15.3 0.9 1.6 1 0 0 1 1 1 1 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Arabinose_Isome PF02610.15 OAG07715.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 L-arabinose isomerase Mtc PF03820.17 OAG07716.1 - 0.3 10.1 1.7 0.44 9.6 1.7 1.2 1 0 0 1 1 1 0 Tricarboxylate carrier Hce2 PF14856.6 OAG07719.1 - 6.6e-07 29.6 2.0 1.4e-06 28.5 0.9 2.0 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor ABC_tran PF00005.27 OAG07721.1 - 2.3e-47 160.9 0.0 8.8e-26 91.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG07721.1 - 2.7e-34 119.1 28.3 2.2e-28 99.7 13.4 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG07721.1 - 8.7e-12 44.9 0.8 0.0027 17.2 0.1 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG07721.1 - 6.2e-08 32.8 0.1 0.14 11.9 0.0 4.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG07721.1 - 6.6e-06 26.1 0.6 0.02 14.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OAG07721.1 - 4.4e-05 23.1 0.7 0.16 11.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG07721.1 - 4.9e-05 23.8 2.2 0.082 13.3 0.3 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG07721.1 - 0.0011 19.2 1.1 1 9.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 OAG07721.1 - 0.0014 17.8 1.7 1.4 7.9 0.2 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_7 PF12775.7 OAG07721.1 - 0.0027 17.3 0.8 3.6 7.1 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OAG07721.1 - 0.0037 17.3 1.1 0.9 9.6 0.2 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 OAG07721.1 - 0.0062 15.8 0.5 2.4 7.4 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 OAG07721.1 - 0.0063 15.7 0.1 1.7 7.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 OAG07721.1 - 0.0074 16.8 0.1 3.7 8.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 OAG07721.1 - 0.012 14.6 0.4 4.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 OAG07721.1 - 0.013 16.0 0.4 1.3 9.5 0.0 3.5 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OAG07721.1 - 0.022 13.9 0.7 4 6.5 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.6 OAG07721.1 - 0.024 14.9 0.2 6.3 7.1 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 OAG07721.1 - 0.047 13.3 1.5 2 8.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain KAP_NTPase PF07693.14 OAG07721.1 - 0.087 12.0 0.7 1.9 7.6 0.0 2.8 3 0 0 3 3 3 0 KAP family P-loop domain DUF87 PF01935.17 OAG07721.1 - 0.14 12.3 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_15 PF13175.6 OAG07721.1 - 0.18 11.5 0.0 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 OAG07721.1 - 0.18 11.4 4.3 6.3 6.4 0.2 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 OAG07721.1 - 0.22 10.3 1.7 6.4 5.5 0.3 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 OAG07721.1 - 0.38 10.6 2.1 23 4.8 0.1 3.3 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OAG07721.1 - 0.4 10.6 3.3 11 5.9 0.2 2.7 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 OAG07721.1 - 0.68 9.9 2.7 42 4.1 0.3 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NDUF_B8 PF05821.11 OAG07722.1 - 1.6e-07 31.4 0.1 1.9e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) adh_short PF00106.25 OAG07723.1 - 1.3e-39 135.7 0.1 1.6e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07723.1 - 2.8e-29 102.3 0.3 3.4e-29 102.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07723.1 - 1.4e-07 31.6 0.1 2.3e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG07723.1 - 0.00061 19.0 0.0 0.001 18.3 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 OAG07723.1 - 0.0029 18.1 0.1 0.0061 17.1 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OAG07723.1 - 0.02 15.0 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OAG07723.1 - 0.026 14.2 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAG07723.1 - 0.039 13.8 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain efb-c PF12199.8 OAG07723.1 - 0.042 13.9 1.1 0.21 11.7 0.0 2.3 1 1 1 2 2 2 0 Extracellular fibrinogen binding protein C terminal Helicase_RecD PF05127.14 OAG07723.1 - 0.094 12.6 0.2 0.16 11.8 0.2 1.5 1 1 0 1 1 1 0 Helicase Mei5 PF10376.9 OAG07724.1 - 0.24 11.3 15.4 0.52 10.1 11.0 3.3 2 1 0 2 2 2 0 Double-strand recombination repair protein GWT1 PF06423.12 OAG07725.1 - 5e-43 146.8 2.1 5e-43 146.8 2.1 2.1 2 1 1 3 3 3 1 GWT1 DUF4818 PF16089.5 OAG07725.1 - 0.0012 19.3 0.0 0.0012 19.3 0.0 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4818) DUF4896 PF16237.5 OAG07725.1 - 0.0033 17.2 2.4 0.19 11.6 1.3 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4896) zf-Tim10_DDP PF02953.15 OAG07727.1 - 1.3e-19 69.6 2.3 1.6e-19 69.3 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phtf-FEM1B_bdg PF12129.8 OAG07729.1 - 6.7 6.5 11.5 0.19 11.5 4.3 2.2 2 1 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Mpv17_PMP22 PF04117.12 OAG07730.1 - 3.9e-20 71.8 3.2 7.6e-20 70.9 3.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pkinase PF00069.25 OAG07731.1 - 4.9e-65 219.5 0.0 7.4e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07731.1 - 1.1e-36 126.5 0.0 7.6e-31 107.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG07731.1 - 4.6e-07 29.5 0.0 0.00085 18.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAG07731.1 - 0.0011 18.9 0.1 0.0031 17.5 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG07731.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OAG07731.1 - 0.018 14.0 0.3 0.027 13.4 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAG07731.1 - 0.032 13.6 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_2 PF07992.14 OAG07732.1 - 6.6e-50 170.0 3.6 8.6e-50 169.6 3.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 OAG07732.1 - 1e-15 57.4 0.0 2.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OAG07732.1 - 6.1e-15 55.5 0.9 6.1e-15 55.5 0.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 OAG07732.1 - 1.1e-07 32.3 0.0 1.5e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Reductase C-terminal Pyr_redox_3 PF13738.6 OAG07732.1 - 7.7e-07 28.7 0.1 0.027 13.7 0.3 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAG07732.1 - 6.8e-05 22.7 0.0 0.00025 20.9 0.0 2.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 OAG07732.1 - 0.075 13.0 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Redoxin PF08534.10 OAG07733.1 - 4e-08 33.1 0.0 5.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG07733.1 - 1e-07 31.9 0.0 4.1e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family Podoplanin PF05808.11 OAG07734.1 - 7.5e-05 22.9 0.8 0.00012 22.3 0.8 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 OAG07734.1 - 0.0099 15.3 0.1 0.022 14.2 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GAPT PF11770.8 OAG07734.1 - 0.91 9.4 3.9 13 5.6 0.0 2.3 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) Glyco_hydro_31 PF01055.26 OAG07735.1 - 5.8e-149 497.0 6.5 7.4e-149 496.7 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG07735.1 - 1.9e-31 108.7 0.0 3.8e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Rotavirus_VP7 PF05868.11 OAG07735.1 - 0.00017 21.1 0.4 0.0013 18.1 0.2 2.5 2 1 1 3 3 3 1 Rotavirus major outer capsid protein VP7 Gal_mutarotas_2 PF13802.6 OAG07735.1 - 0.0015 18.8 0.1 0.0047 17.2 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like MAGI_u5 PF16666.5 OAG07736.1 - 0.01 16.0 5.2 0.014 15.6 5.2 1.2 1 0 0 1 1 1 0 Unstructured region on MAGI Fib_alpha PF08702.10 OAG07737.1 - 0.0019 18.4 11.4 0.0052 17.0 3.0 2.9 2 1 0 2 2 2 2 Fibrinogen alpha/beta chain family Prok-TraM PF09228.10 OAG07737.1 - 0.58 10.5 9.5 0.11 12.8 4.2 2.3 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Musclin PF11037.8 OAG07737.1 - 1.6 8.7 5.1 1.2 9.0 0.6 2.6 1 1 1 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle DUF5365 PF17326.2 OAG07737.1 - 1.6 9.1 4.4 0.62 10.5 1.6 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5365) SlyX PF04102.12 OAG07737.1 - 1.7 9.3 19.3 5.7 7.6 9.7 3.7 2 1 1 3 3 3 0 SlyX GAS PF13851.6 OAG07737.1 - 1.9 7.8 22.1 2.9 7.2 17.4 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Pox_F11 PF04943.12 OAG07737.1 - 1.9 7.5 6.9 3 6.8 6.9 1.3 1 0 0 1 1 1 0 Poxvirus F11 protein NPV_P10 PF05531.12 OAG07737.1 - 7.5 7.1 6.4 14 6.3 3.8 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ECH_1 PF00378.20 OAG07738.1 - 8.2e-43 146.5 0.0 1e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG07738.1 - 4.5e-20 72.4 0.2 1.1e-19 71.1 0.2 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribosomal_L18A PF01775.17 OAG07739.1 - 6.7e-55 184.4 0.7 8.6e-55 184.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 OAG07740.1 - 6.1e-12 46.0 0.0 1.2e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain BTB PF00651.31 OAG07741.1 - 2.7e-08 34.0 0.0 7.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain LppC PF04348.13 OAG07741.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 LppC putative lipoprotein CBP_CCPA PF17040.5 OAG07741.1 - 0.074 13.6 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 Cellulose-complementing protein A Clr2_transil PF16761.5 OAG07742.1 - 8.7e-19 68.1 1.4 2.2e-18 66.9 0.4 2.2 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 OAG07742.1 - 7.5e-13 49.5 0.0 2.6e-11 44.5 0.0 2.6 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 NAM-associated PF14303.6 OAG07743.1 - 0.033 14.9 0.1 0.077 13.7 0.1 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain ETRAMP PF09716.10 OAG07743.1 - 0.07 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF1180 PF06679.12 OAG07743.1 - 2.2 8.7 4.4 2 8.8 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Nucleopor_Nup85 PF07575.13 OAG07744.1 - 1.2e-21 77.0 0.1 5e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 Nup85 Nucleoporin PI3K_1B_p101 PF10486.9 OAG07744.1 - 0.016 13.0 1.2 0.027 12.3 1.2 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AC_N PF16214.5 OAG07744.1 - 0.42 9.7 1.6 0.62 9.1 1.6 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Ysc84 PF04366.12 OAG07746.1 - 1.3e-46 157.5 0.0 2e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator 2OG-FeII_Oxy_3 PF13640.6 OAG07747.1 - 7.7e-11 42.7 0.0 1.2e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OAG07747.1 - 0.026 15.2 0.0 0.04 14.6 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 OAG07747.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein RGS PF00615.19 OAG07748.1 - 1.4e-13 51.2 0.0 2.2e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF155 PF02582.14 OAG07749.1 - 8.5e-56 188.8 0.1 1.7e-55 187.8 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 HLH PF00010.26 OAG07750.1 - 1.1e-12 47.6 0.1 3.1e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 OAG07750.1 - 2.6 7.9 4.8 0.67 9.8 1.1 1.8 2 0 0 2 2 2 0 Septum formation initiator Kelch_3 PF13415.6 OAG07752.1 - 0.036 14.4 0.1 0.062 13.6 0.1 1.4 1 0 0 1 1 1 0 Galactose oxidase, central domain SBF PF01758.16 OAG07753.1 - 4.2e-51 173.4 6.5 4.2e-51 173.4 6.5 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family PIG-P PF08510.12 OAG07753.1 - 0.56 10.1 3.2 16 5.4 0.1 3.0 2 1 0 2 2 2 0 PIG-P Methyltransf_23 PF13489.6 OAG07754.1 - 3.3e-11 43.3 0.0 6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG07754.1 - 0.01 16.5 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG07754.1 - 0.084 13.6 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Arrestin_N PF00339.29 OAG07758.1 - 1e-07 32.1 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 OAG07758.1 - 1.7e-07 30.4 0.2 9.6e-06 24.6 0.1 2.5 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 OAG07758.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus ATG16 PF08614.11 OAG07759.1 - 7.1e-07 29.7 233.8 1.1e-05 25.8 14.0 14.9 1 1 12 15 15 15 9 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 OAG07759.1 - 0.00035 20.6 219.2 0.063 13.3 15.4 13.8 3 2 8 13 13 13 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 OAG07759.1 - 0.00074 19.1 13.9 0.00074 19.1 13.9 9.0 3 1 6 9 9 9 2 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 OAG07759.1 - 3.9 6.3 203.9 0.021 13.7 16.1 11.9 3 1 11 14 14 14 0 Spc7 kinetochore protein RasGEF_N_2 PF14663.6 OAG07759.1 - 6.1 7.3 9.7 11 6.5 0.3 4.9 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Acyl-CoA_dh_1 PF00441.24 OAG07760.1 - 6.6e-38 130.3 4.8 1e-37 129.6 4.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG07760.1 - 4.1e-30 104.7 0.0 9.6e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG07760.1 - 6.8e-24 83.9 0.0 1.4e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG07760.1 - 4.2e-17 62.7 0.9 6.4e-17 62.1 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAG07760.1 - 0.00061 19.5 0.1 0.0021 17.8 0.0 1.8 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 OAG07760.1 - 0.011 15.8 0.0 0.043 13.9 0.0 2.0 1 0 0 1 1 1 0 Staphylococcal AgrD protein GMC_oxred_N PF00732.19 OAG07761.1 - 5.6e-52 176.9 0.0 7.1e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG07761.1 - 9.4e-35 120.2 0.0 2e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG07761.1 - 0.002 17.8 0.3 1.1 8.7 0.0 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG07761.1 - 0.0036 16.4 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG07761.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG07761.1 - 0.11 11.6 0.0 0.89 8.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAG07762.1 - 1.1e-26 93.5 0.4 1.5e-26 93.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07762.1 - 1.9e-20 73.4 0.5 3.9e-20 72.4 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07762.1 - 2.2e-13 50.5 0.1 3.2e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG07762.1 - 0.0002 20.6 0.0 0.00026 20.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ANAPC4_WD40 PF12894.7 OAG07764.1 - 4.7e-17 62.1 5.3 7.9e-06 26.1 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG07764.1 - 1.4e-14 54.3 16.1 0.0027 18.5 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAG07764.1 - 9.5e-07 28.1 0.1 0.00011 21.3 0.0 3.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG07764.1 - 4.2e-06 26.8 2.4 0.00027 20.9 0.3 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.6 OAG07765.1 - 1.3e-28 98.7 4.8 4.6e-08 33.0 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG07765.1 - 1.8e-25 88.4 0.9 7.1e-07 29.1 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OAG07765.1 - 2.6e-25 87.8 2.7 6.7e-08 32.5 0.3 4.8 2 1 2 4 4 4 4 Kelch motif Kelch_3 PF13415.6 OAG07765.1 - 7.4e-21 73.9 10.2 5.6e-07 29.7 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OAG07765.1 - 5.5e-20 70.7 0.3 0.00012 21.6 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OAG07765.1 - 2e-16 59.2 2.1 5.5e-05 23.0 0.1 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 OAG07765.1 - 7.4e-07 29.4 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CssAB PF16831.5 OAG07767.1 - 0.12 12.8 0.4 0.13 12.6 0.4 1.2 1 0 0 1 1 1 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 PET117 PF15786.5 OAG07770.1 - 3.9e-25 87.9 1.7 4.5e-25 87.7 1.7 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial V-ATPase_G PF03179.15 OAG07771.1 - 8.3e-31 106.6 15.5 9.3e-31 106.5 15.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit SHE3 PF17078.5 OAG07771.1 - 0.00026 20.8 4.5 0.0003 20.6 4.5 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 RRF PF01765.19 OAG07771.1 - 0.0022 18.0 10.9 0.0031 17.5 10.9 1.3 1 0 0 1 1 1 1 Ribosome recycling factor DUF3552 PF12072.8 OAG07771.1 - 0.014 14.8 16.3 0.021 14.2 15.8 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 OAG07771.1 - 0.087 12.9 13.9 0.034 14.2 10.3 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 OAG07771.1 - 0.14 12.6 8.8 0.2 12.1 8.8 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP11 PF06644.11 OAG07771.1 - 2.6 7.8 10.6 3.4 7.4 10.6 1.1 1 0 0 1 1 1 0 ATP11 protein DUF883 PF05957.13 OAG07771.1 - 3.6 8.3 9.6 6.6 7.4 4.5 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ALGX PF16822.5 OAG07772.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Arrestin_N PF00339.29 OAG07773.1 - 4.7e-10 39.7 0.0 7e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 OAG07773.1 - 0.078 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Bul1 C terminus Arrestin_C PF02752.22 OAG07773.1 - 0.5 10.8 4.3 2.7 8.5 1.4 2.7 2 2 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain MMPL PF03176.15 OAG07775.1 - 0.065 12.2 0.1 0.07 12.1 0.1 1.1 1 0 0 1 1 1 0 MMPL family SCP2 PF02036.17 OAG07776.1 - 2e-25 89.2 0.4 2.3e-25 89.0 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAG07776.1 - 8.4e-07 29.3 0.1 1.2e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 OAG07776.1 - 0.042 14.2 0.0 0.056 13.9 0.0 1.3 1 0 0 1 1 1 0 Sterol carrier protein domain GMC_oxred_N PF00732.19 OAG07777.1 - 4.3e-65 220.0 0.0 5.6e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG07777.1 - 9.9e-35 120.2 0.1 1.9e-34 119.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG07777.1 - 2e-06 27.7 0.1 4.5e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG07777.1 - 9.3e-05 21.6 1.5 0.00022 20.4 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG07777.1 - 0.00019 21.6 0.2 0.00057 20.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG07777.1 - 0.0085 15.2 1.9 0.025 13.7 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG07777.1 - 0.0087 15.3 0.1 0.034 13.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG07777.1 - 0.014 14.6 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAG07777.1 - 0.023 14.0 0.2 3.9 6.6 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG07777.1 - 0.037 12.7 0.1 0.082 11.6 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.6 OAG07778.1 - 7.5e-08 32.5 0.2 1.2e-07 31.9 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG07778.1 - 0.004 16.7 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG07778.1 - 0.029 14.6 0.1 0.042 14.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 OAG07779.1 - 1.2e-33 116.6 22.5 1.2e-33 116.6 22.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG07779.1 - 9.9e-05 21.8 0.3 9.9e-05 21.8 0.3 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Inhibitor_I53 PF11714.8 OAG07779.1 - 0.085 13.1 0.1 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Amidase PF01425.21 OAG07780.1 - 7.2e-105 351.6 0.0 1.4e-104 350.6 0.0 1.4 1 1 0 1 1 1 1 Amidase NAM-associated PF14303.6 OAG07781.1 - 0.22 12.2 2.6 0.46 11.2 2.6 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain LNS2 PF08235.13 OAG07782.1 - 9.8e-94 313.0 0.0 1.5e-93 312.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OAG07782.1 - 9.5e-43 144.3 0.0 1.8e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 OAG07782.1 - 0.072 12.7 0.0 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) CDC45 PF02724.14 OAG07782.1 - 3 6.0 17.8 5.2 5.2 17.8 1.3 1 0 0 1 1 1 0 CDC45-like protein fn3 PF00041.21 OAG07783.1 - 5.6e-08 33.0 0.0 1.6e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain DUF812 PF05667.11 OAG07783.1 - 0.0016 17.4 24.6 0.0016 17.4 24.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF812) PAM2 PF07145.15 OAG07783.1 - 1 9.2 4.2 15 5.5 0.5 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region TFIID-31kDa PF02291.15 OAG07784.1 - 3.3e-45 153.1 0.0 3.8e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Cmc1 PF08583.10 OAG07785.1 - 4.5e-15 55.4 4.0 1.1e-14 54.2 4.0 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 OAG07785.1 - 0.018 15.4 0.5 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 OAG07785.1 - 0.023 14.7 0.5 0.046 13.7 0.5 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Tyrosinase PF00264.20 OAG07786.1 - 2.2e-46 158.9 0.6 3.1e-46 158.4 0.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF5347 PF17282.2 OAG07786.1 - 0.18 12.1 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5347) PPP4R2 PF09184.11 OAG07787.1 - 3e-09 36.9 11.7 3e-08 33.6 11.3 2.3 1 1 0 1 1 1 1 PPP4R2 PsiA PF06952.11 OAG07787.1 - 0.18 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 PsiA protein GCOM2 PF15328.6 OAG07788.1 - 0.0022 18.4 5.2 0.0067 16.8 5.2 1.8 1 0 0 1 1 1 1 Putative GRINL1B complex locus protein 2 GFA PF04828.14 OAG07789.1 - 0.018 15.4 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 OAG07789.1 - 0.024 14.7 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon TMEM82 PF15816.5 OAG07789.1 - 0.082 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 82 Glyco_hydro_72 PF03198.14 OAG07790.1 - 1.1e-38 133.3 0.3 1.4e-38 132.9 0.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 OAG07791.1 - 0.00051 20.7 0.2 0.00084 20.0 0.2 1.4 1 0 0 1 1 1 1 X8 domain Hyd_WA PF06462.12 OAG07791.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Propeller Beta-lactamase PF00144.24 OAG07792.1 - 4.7e-48 164.1 0.5 7.3e-48 163.5 0.3 1.4 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 OAG07792.1 - 0.0063 17.0 0.1 0.017 15.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) RNA_pol_Rpb1_5 PF04998.17 OAG07793.1 - 2.8e-102 341.7 0.1 4.3e-102 341.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OAG07793.1 - 3.5e-102 341.9 0.0 1.2e-101 340.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OAG07793.1 - 2.5e-75 252.3 0.0 5.6e-75 251.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OAG07793.1 - 8e-62 208.5 0.4 2.1e-61 207.1 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 OAG07793.1 - 6e-46 156.2 0.0 1.9e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 OAG07793.1 - 2.2e-35 121.6 5.8 5.7e-35 120.2 5.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 OAG07793.1 - 4.2e-33 113.5 0.0 1.2e-32 112.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OAG07793.1 - 8.5e-13 47.9 198.9 0.0017 18.6 10.4 13.3 13 1 1 14 14 14 10 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 OAG07794.1 - 1.7e-12 47.6 9.9 0.00025 21.7 0.3 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG07794.1 - 9.8e-10 38.6 2.6 3.3e-06 27.3 0.0 4.4 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cellulase PF00150.18 OAG07795.1 - 5.5e-18 65.4 2.3 5.2e-17 62.2 2.3 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chal_sti_synt_N PF00195.19 OAG07797.1 - 1e-20 74.1 0.0 1.8e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 OAG07797.1 - 2.1e-18 66.7 0.0 3.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 OAG07797.1 - 2e-05 24.7 0.0 5.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 OAG07797.1 - 5.9e-05 22.5 0.0 7.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein DUF4022 PF13214.6 OAG07798.1 - 0.023 14.9 0.6 0.049 13.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) Fe_dep_repress PF01325.19 OAG07799.1 - 0.019 15.2 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain ABC2_membrane PF01061.24 OAG07801.1 - 2.2e-68 229.8 60.6 1.3e-42 145.6 27.6 3.9 3 1 1 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.27 OAG07801.1 - 3.1e-32 111.9 0.0 1.9e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG07801.1 - 1.7e-30 104.8 12.7 1.1e-28 98.9 0.1 4.6 5 0 0 5 5 4 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG07801.1 - 3.4e-17 62.8 0.2 7.9e-17 61.7 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG07801.1 - 7.1e-08 31.9 48.8 3.1e-06 26.5 19.9 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 OAG07801.1 - 1.7e-06 28.5 0.1 0.0066 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG07801.1 - 3.1e-06 27.2 0.8 0.00053 19.9 0.1 2.7 2 1 1 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 OAG07801.1 - 2.4e-05 24.0 0.0 0.00045 19.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG07801.1 - 6.4e-05 23.5 0.0 0.019 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG07801.1 - 0.00025 21.0 0.0 0.77 9.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OAG07801.1 - 0.00027 21.1 0.2 0.17 12.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OAG07801.1 - 0.00041 20.0 0.7 0.049 13.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 OAG07801.1 - 0.00061 20.2 1.4 0.18 12.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 OAG07801.1 - 0.0012 18.4 0.0 0.18 11.2 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 OAG07801.1 - 0.0043 16.8 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG07801.1 - 0.021 15.1 0.2 4.9 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG07801.1 - 0.023 15.1 0.1 8.6 6.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG07801.1 - 0.026 14.5 1.9 3.6 7.5 0.2 2.7 3 0 0 3 3 2 0 NACHT domain cobW PF02492.19 OAG07801.1 - 0.043 13.4 1.0 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 OAG07801.1 - 0.05 13.9 0.6 2.4 8.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 OAG07801.1 - 0.14 10.8 0.1 22 3.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OAG07801.1 - 0.23 11.6 0.2 37 4.4 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAG07801.1 - 0.27 10.9 1.1 19 4.9 0.3 3.1 3 0 0 3 3 3 0 AAA domain PyrBI_leader PF08052.11 OAG07801.1 - 0.28 11.2 2.7 0.93 9.5 2.0 2.1 2 0 0 2 2 2 0 PyrBI operon leader peptide DUF4181 PF13789.6 OAG07802.1 - 0.012 15.9 2.3 0.012 15.9 2.3 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4181) DUF2826 PF11442.8 OAG07802.1 - 0.029 14.2 0.3 0.029 14.2 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2826) Glyco_transf_28 PF03033.20 OAG07803.1 - 2.2e-18 66.6 0.1 3.9e-17 62.6 0.1 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG07803.1 - 1.7e-08 33.7 0.0 2.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG07803.1 - 0.00039 20.4 0.5 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 OAG07803.1 - 0.0015 18.8 0.0 0.005 17.2 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF3328 PF11807.8 OAG07803.1 - 0.17 11.6 0.6 3.6 7.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) RAP80_UIM PF18282.1 OAG07803.1 - 0.19 11.6 11.0 1.7 8.5 2.7 3.3 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 OAG07803.1 - 0.93 9.6 28.6 0.074 13.0 1.6 4.7 4 0 0 4 4 4 0 Ubiquitin interaction motif Asparaginase_2 PF01112.18 OAG07804.1 - 7.3e-71 238.7 1.1 9.8e-71 238.3 1.1 1.0 1 0 0 1 1 1 1 Asparaginase zinc_ribbon_16 PF17034.5 OAG07805.1 - 0.0022 18.2 0.3 0.0022 18.2 0.3 1.0 1 0 0 1 1 1 1 Zinc-ribbon like family Myb_DNA-binding PF00249.31 OAG07806.1 - 3.7e-15 55.9 0.8 4.2e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG07806.1 - 8.8e-09 35.5 1.3 0.00014 22.0 0.0 2.4 2 1 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAG07806.1 - 0.14 12.3 2.3 0.17 12.1 0.5 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Pkinase PF00069.25 OAG07807.1 - 5.1e-49 167.0 0.0 5.7e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07807.1 - 6.4e-29 101.0 0.0 7.6e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG07807.1 - 0.001 18.5 0.1 0.002 17.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG07807.1 - 0.0014 18.6 0.1 0.1 12.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG07807.1 - 0.0082 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAG07807.1 - 0.011 14.7 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG07807.1 - 0.028 13.2 0.0 0.044 12.6 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Cullin_binding PF03556.15 OAG07807.1 - 0.032 14.7 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 Cullin binding Cullin PF00888.22 OAG07808.1 - 4.5e-20 71.8 0.5 5.1e-20 71.6 0.5 1.0 1 0 0 1 1 1 1 Cullin family HET PF06985.11 OAG07811.1 - 8.9e-12 45.6 7.7 2.4e-09 37.7 2.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 OAG07812.1 - 1.1e-20 73.9 0.0 1.4e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07812.1 - 1.3e-15 57.6 0.1 1.6e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07812.1 - 5.4e-11 42.7 0.0 6.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG07812.1 - 0.017 14.6 0.1 0.051 13.0 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG07812.1 - 0.032 14.1 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding OrsD PF12013.8 OAG07813.1 - 2.2e-11 44.2 0.3 5.2e-11 43.0 0.1 1.6 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D FRP PF18032.1 OAG07816.1 - 0.11 13.1 0.1 0.13 12.9 0.1 1.1 1 0 0 1 1 1 0 Photoprotection regulator fluorescence recovery protein MRP-L28 PF09812.9 OAG07817.1 - 0.00037 20.7 0.0 0.00059 20.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 OAG07818.1 - 2e-47 160.8 0.0 2.3e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG07818.1 - 6.7e-22 78.0 0.0 1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG07818.1 - 5.9e-08 32.4 0.0 8.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG07818.1 - 0.008 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAG07818.1 - 0.015 14.7 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OAG07818.1 - 0.13 12.1 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADH_zinc_N PF00107.26 OAG07818.1 - 0.14 12.2 0.0 5.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MMR_HSR1 PF01926.23 OAG07818.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG07818.1 - 0.18 12.2 0.2 0.42 11.0 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OAG07818.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 OAG07819.1 - 6e-54 183.1 1.1 6e-54 183.1 1.1 4.4 3 1 1 4 4 4 1 Salt tolerance down-regulator Coilin_N PF15862.5 OAG07819.1 - 0.0038 17.0 0.0 0.0038 17.0 0.0 5.5 2 1 2 4 4 4 1 Coilin N-terminus DUF4746 PF15928.5 OAG07819.1 - 0.069 12.6 0.0 0.069 12.6 0.0 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4746) DUF5423 PF17461.2 OAG07821.1 - 0.056 12.3 5.1 0.063 12.1 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Kei1 PF08552.11 OAG07821.1 - 0.39 10.6 1.5 0.45 10.4 1.5 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 VIT1 PF01988.19 OAG07822.1 - 4e-62 209.9 1.8 4.5e-62 209.7 1.8 1.0 1 0 0 1 1 1 1 VIT family MFS_1 PF07690.16 OAG07823.1 - 3.1e-41 141.5 43.7 3.1e-41 141.5 43.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG07823.1 - 1.2e-08 33.9 20.0 1.6e-08 33.4 20.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GFO_IDH_MocA PF01408.22 OAG07824.1 - 2.1e-20 73.7 0.0 3.6e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pab87_oct PF13969.6 OAG07824.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Pab87 octamerisation domain Semialdhyde_dh PF01118.24 OAG07824.1 - 0.035 14.5 0.0 0.085 13.3 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding PF00501.28 OAG07825.1 - 6.5e-75 252.3 0.1 1.1e-74 251.6 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 OAG07825.1 - 1.3e-69 234.6 0.0 2.6e-69 233.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 OAG07825.1 - 5.7e-58 196.7 0.0 9.3e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 OAG07825.1 - 4.9e-54 183.0 0.0 5.6e-52 176.3 0.0 2.9 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 OAG07825.1 - 6.3e-52 176.7 0.0 1.1e-51 175.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 OAG07825.1 - 1.2e-44 153.1 0.6 2.3e-44 152.2 0.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG07825.1 - 4.9e-32 110.4 0.1 1.7e-31 108.7 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 OAG07825.1 - 6.4e-30 104.2 0.0 4.3e-29 101.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 OAG07825.1 - 1.3e-20 73.5 0.4 8.1e-11 42.1 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 OAG07825.1 - 5.1e-16 58.9 0.0 9.1e-11 41.7 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 OAG07825.1 - 2e-13 50.8 0.0 8.8e-13 48.7 0.0 2.2 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OAG07825.1 - 2.7e-13 49.8 0.0 7.3e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.12 OAG07825.1 - 3.2e-12 47.1 0.0 1.5e-11 44.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG07825.1 - 2.4e-10 40.5 0.0 5.9e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG07825.1 - 8.8e-10 39.2 0.0 6.8e-09 36.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.19 OAG07825.1 - 7e-08 31.8 0.0 5.2e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.12 OAG07825.1 - 9.4e-08 32.6 0.0 3.7e-07 30.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 OAG07825.1 - 2.9e-06 27.3 0.0 0.00041 20.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)H-binding Methyltransf_31 PF13847.6 OAG07825.1 - 6.1e-06 26.1 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 OAG07825.1 - 1.9e-05 24.4 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 OAG07825.1 - 8.4e-05 22.1 0.1 0.00021 20.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 OAG07825.1 - 8.9e-05 22.0 0.0 0.013 14.9 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG07825.1 - 0.017 14.3 0.0 1.4 7.9 0.0 2.6 2 0 0 2 2 2 0 RmlD substrate binding domain Methyltransf_16 PF10294.9 OAG07825.1 - 0.054 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_33 PF10017.9 OAG07825.1 - 0.074 12.2 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Ubie_methyltran PF01209.18 OAG07825.1 - 0.1 11.9 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Aldo_ket_red PF00248.21 OAG07826.1 - 9.1e-50 169.5 0.0 1e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 OAG07827.1 - 8.1e-53 179.7 0.0 1e-52 179.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG07827.1 - 1.8e-30 106.4 0.1 3.2e-30 105.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG07827.1 - 6e-05 22.3 0.1 9.3e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG07827.1 - 0.0016 18.6 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG07827.1 - 0.0031 16.8 0.2 0.0074 15.5 0.2 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAG07827.1 - 0.044 12.8 0.3 0.11 11.6 0.3 1.6 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAG07827.1 - 0.06 12.9 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Zn_clus PF00172.18 OAG07828.1 - 5.8e-06 26.3 10.1 9.8e-06 25.6 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 OAG07829.1 - 9.1e-22 77.8 0.7 9.5e-14 51.4 0.2 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG07829.1 - 2.6e-07 30.2 0.0 0.00054 19.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG07829.1 - 2.2e-06 27.8 0.1 6.6e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG07829.1 - 0.00062 19.1 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG07829.1 - 0.00067 20.2 0.0 0.13 12.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG07829.1 - 0.0029 17.0 0.2 0.21 10.8 0.1 2.4 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAG07829.1 - 0.0044 16.1 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OAG07829.1 - 0.0075 16.3 0.1 6.4 6.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding SE PF08491.10 OAG07829.1 - 0.018 14.1 0.0 0.059 12.4 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 OAG07829.1 - 0.031 13.9 0.2 0.32 10.5 0.1 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG07829.1 - 0.051 12.6 0.0 0.57 9.2 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_2 PF03446.15 OAG07829.1 - 0.16 12.1 0.0 2.5 8.3 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase UBM PF14377.6 OAG07829.1 - 0.23 10.9 2.5 5.1 6.7 0.8 2.9 2 0 0 2 2 2 0 Ubiquitin binding region DIOX_N PF14226.6 OAG07830.1 - 5.3e-27 94.9 0.0 1.4e-26 93.6 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG07830.1 - 1.9e-17 63.6 0.0 3.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_4 PF01565.23 OAG07831.1 - 1.5e-21 76.6 1.5 2.6e-21 75.8 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG07831.1 - 6.6e-12 45.3 0.3 1.2e-11 44.5 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 OAG07832.1 - 1.7e-18 66.7 1.3 3.1e-18 65.8 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG07832.1 - 2.4e-06 27.6 0.7 5e-06 26.5 0.2 1.8 2 0 0 2 2 2 1 Berberine and berberine like HTH_Tnp_Tc5 PF03221.16 OAG07833.1 - 1.5e-06 28.1 0.1 3.3e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Drf_GBD PF06371.13 OAG07833.1 - 0.014 15.0 0.4 0.014 15.0 0.4 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF3945 PF13101.6 OAG07833.1 - 0.086 12.6 0.5 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Nop14 PF04147.12 OAG07834.1 - 0.44 8.7 14.6 0.65 8.1 14.6 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAG07834.1 - 0.46 9.8 14.1 0.73 9.2 14.1 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAG07834.1 - 2.1 6.6 12.8 0.35 9.1 8.4 1.7 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_phi PF04931.13 OAG07834.1 - 2.3 6.2 18.7 3 5.8 18.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 OAG07834.1 - 2.6 7.4 16.7 4.8 6.5 16.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 OAG07834.1 - 2.8 7.2 13.0 5.6 6.2 13.0 1.4 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 OAG07834.1 - 9.9 5.2 15.5 16 4.5 15.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein COesterase PF00135.28 OAG07835.1 - 6.3e-63 213.4 0.0 8.1e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG07835.1 - 2.7e-06 27.4 0.1 0.052 13.4 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2974 PF11187.8 OAG07835.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 OAG07835.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 OAG07835.1 - 0.12 12.0 0.0 0.45 10.1 0.0 1.8 1 1 0 1 1 1 0 Putative esterase Sugar_tr PF00083.24 OAG07836.1 - 3.4e-77 260.2 24.6 3.9e-77 260.0 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07836.1 - 1.5e-19 70.2 40.5 4.1e-19 68.7 34.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAG07837.1 - 2.4e-05 24.3 15.1 2.4e-05 24.3 15.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_32N PF00251.20 OAG07838.1 - 8e-40 137.3 0.0 2.4e-39 135.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAG07838.1 - 5.2e-28 98.0 0.0 7.6e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 OAG07838.1 - 1.3 9.4 3.4 11 6.5 0.2 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat EBP PF05241.12 OAG07839.1 - 0.0052 16.3 0.1 0.006 16.1 0.1 1.3 1 0 0 1 1 1 1 Emopamil binding protein Cation_ATPase_C PF00689.21 OAG07839.1 - 0.28 10.9 4.1 0.62 9.7 4.3 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Zn_clus PF00172.18 OAG07840.1 - 2.1e-08 34.2 7.7 3.7e-08 33.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG07840.1 - 1.3e-06 27.5 5.5 1.6e-06 27.2 5.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain LisH_TPL PF17814.1 OAG07840.1 - 0.092 12.4 0.5 0.22 11.2 0.5 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain BNR_2 PF13088.6 OAG07841.1 - 0.00023 20.6 0.1 0.00043 19.7 0.1 1.4 1 1 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 OAG07841.1 - 0.05 12.4 1.2 4 6.1 0.1 2.3 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 OAG07841.1 - 0.32 11.1 3.6 0.79 10.0 0.2 3.6 3 0 0 3 3 3 0 BNR/Asp-box repeat Glyco_hydro_3_C PF01915.22 OAG07842.1 - 2.8e-37 128.7 0.0 4.8e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG07842.1 - 3.5e-28 98.9 0.0 5.2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG07842.1 - 1.3e-05 25.3 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_tran PF00005.27 OAG07843.1 - 1.4e-42 145.4 0.0 5e-23 82.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG07843.1 - 9.6e-32 110.7 37.4 4.4e-26 92.2 6.7 3.1 3 1 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG07843.1 - 1.4e-11 44.2 0.2 0.051 13.0 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG07843.1 - 8.2e-11 42.2 0.0 0.00056 19.8 0.0 3.6 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAG07843.1 - 1.2e-07 32.1 0.2 0.0005 20.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 OAG07843.1 - 2.5e-07 30.3 0.1 0.00098 18.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG07843.1 - 6.3e-06 26.2 0.2 0.0067 16.4 0.0 2.7 3 0 0 3 3 2 1 RsgA GTPase AAA_23 PF13476.6 OAG07843.1 - 8.1e-06 26.5 0.1 0.0027 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG07843.1 - 1.3e-05 25.7 0.2 0.0035 17.7 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 OAG07843.1 - 1.4e-05 25.1 2.1 0.0086 16.0 0.0 3.4 3 0 0 3 3 3 1 NTPase AAA_33 PF13671.6 OAG07843.1 - 4.5e-05 23.6 0.0 0.02 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG07843.1 - 5e-05 23.3 0.0 0.047 13.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 OAG07843.1 - 7.7e-05 22.0 0.0 0.0022 17.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain T2SSE PF00437.20 OAG07843.1 - 7.9e-05 21.8 0.0 0.0011 18.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 OAG07843.1 - 0.00013 22.1 0.2 0.08 13.0 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 OAG07843.1 - 0.00013 21.7 0.0 0.26 11.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAG07843.1 - 0.00014 21.7 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAG07843.1 - 0.00021 20.9 0.6 0.86 9.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain Pox_A32 PF04665.12 OAG07843.1 - 0.00026 20.5 0.1 0.066 12.7 0.0 2.8 3 0 0 3 3 3 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 OAG07843.1 - 0.00036 20.0 0.1 0.76 9.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Roc PF08477.13 OAG07843.1 - 0.00056 20.1 0.2 0.77 10.0 0.0 3.0 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 OAG07843.1 - 0.0014 18.8 0.2 0.32 11.3 0.1 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 OAG07843.1 - 0.0018 18.6 0.6 0.59 10.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG07843.1 - 0.002 17.7 0.1 3.2 7.2 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OAG07843.1 - 0.0023 18.0 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG07843.1 - 0.0028 17.7 0.1 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin family IstB_IS21 PF01695.17 OAG07843.1 - 0.0028 17.4 1.1 6.2 6.5 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 OAG07843.1 - 0.003 17.2 0.8 0.076 12.6 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 OAG07843.1 - 0.0041 16.1 0.4 2.2 7.1 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 OAG07843.1 - 0.0049 16.8 0.0 0.16 11.8 0.0 3.0 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 OAG07843.1 - 0.0049 17.4 0.0 5 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG07843.1 - 0.0081 16.6 0.1 5.7 7.4 0.0 3.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 OAG07843.1 - 0.0089 15.8 1.0 5.3 6.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 OAG07843.1 - 0.0099 16.3 0.0 4.9 7.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Viral_helicase1 PF01443.18 OAG07843.1 - 0.02 14.7 0.1 0.99 9.1 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 OAG07843.1 - 0.034 14.0 0.0 7.1 6.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OAG07843.1 - 0.05 13.6 0.1 18 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MobB PF03205.14 OAG07843.1 - 0.06 13.2 0.5 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 OAG07843.1 - 0.089 12.5 0.2 0.34 10.6 0.1 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 OAG07843.1 - 0.097 12.4 0.2 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 OAG07843.1 - 0.15 11.8 0.1 8.4 6.1 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase Chlorophyllase PF07224.11 OAG07843.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase FMO-like PF00743.19 OAG07844.1 - 2.2e-16 59.4 0.3 3.4e-14 52.2 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG07844.1 - 1.3e-11 44.5 0.0 1.2e-10 41.4 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG07844.1 - 9.3e-09 34.9 0.0 7.9e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG07844.1 - 3.1e-06 26.6 0.0 0.00037 19.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG07844.1 - 6e-06 26.1 0.0 1.2 8.7 0.0 3.2 2 1 1 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG07844.1 - 0.00022 20.6 0.1 0.043 13.1 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG07844.1 - 0.036 14.1 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAG07844.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 OAG07844.1 - 0.15 12.1 0.0 0.97 9.4 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Amidase PF01425.21 OAG07845.1 - 7.4e-120 400.9 0.4 8.7e-120 400.7 0.4 1.0 1 0 0 1 1 1 1 Amidase OCD_Mu_crystall PF02423.15 OAG07845.1 - 0.044 12.7 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family PGM_PMM_I PF02878.16 OAG07847.1 - 8e-19 67.7 0.1 2.4e-08 33.8 0.0 3.2 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OAG07847.1 - 2.7e-11 43.5 1.4 1.1e-10 41.5 1.4 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OAG07847.1 - 0.00089 19.4 0.1 0.0023 18.1 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAG07847.1 - 0.0024 18.5 0.6 0.03 14.9 0.2 3.0 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Bys1 PF04681.12 OAG07848.1 - 0.011 15.7 0.8 0.018 15.0 0.5 1.6 1 1 0 1 1 1 0 Blastomyces yeast-phase-specific protein NmrA PF05368.13 OAG07849.1 - 3.2e-09 36.7 0.2 7.6e-09 35.5 0.2 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAG07849.1 - 2.1e-07 30.7 0.1 8.1e-05 22.2 0.2 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG07849.1 - 3.1e-07 30.5 0.3 6.5e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 OAG07849.1 - 0.0018 18.4 1.9 0.01 15.9 1.9 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAG07849.1 - 0.0057 17.1 0.1 0.0091 16.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OAG07849.1 - 0.0072 16.2 0.2 0.015 15.2 0.1 1.4 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 OAG07849.1 - 0.025 13.7 0.2 0.045 12.9 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain LpxI_N PF17930.1 OAG07849.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain GXWXG PF14231.6 OAG07849.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 GXWXG protein TrkA_N PF02254.18 OAG07849.1 - 0.09 13.0 0.3 0.19 12.0 0.3 1.7 1 1 0 1 1 1 0 TrkA-N domain Glyco_transf_4 PF13439.6 OAG07849.1 - 0.098 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Shikimate_DH PF01488.20 OAG07849.1 - 0.13 12.3 0.3 0.46 10.5 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Gp_dh_N PF00044.24 OAG07849.1 - 0.15 12.4 0.2 0.56 10.6 0.3 2.0 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ketoacyl-synt PF00109.26 OAG07850.1 - 1.5e-78 263.9 0.1 1.3e-77 260.8 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG07850.1 - 1e-37 130.4 0.0 1.7e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 OAG07850.1 - 3.1e-37 128.6 0.0 8.6e-37 127.1 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 OAG07850.1 - 1.6e-33 115.3 0.5 3.6e-33 114.1 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAG07850.1 - 1.3e-09 38.3 1.0 3.1e-09 37.1 1.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 OAG07850.1 - 4.1e-08 33.7 0.0 1.5e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 OAG07850.1 - 1.2e-05 24.8 0.3 6.4e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_2 PF00891.18 OAG07851.1 - 1.7e-18 66.7 0.0 2.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAG07851.1 - 0.015 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain MarR PF01047.22 OAG07851.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 OAG07851.1 - 0.097 12.7 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 OAG07851.1 - 0.18 11.6 2.1 0.46 10.3 1.1 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain FAD_binding_3 PF01494.19 OAG07852.1 - 2.5e-17 63.2 0.2 5.8e-05 22.5 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 OAG07852.1 - 4e-07 29.5 0.2 0.01 15.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG07852.1 - 1.9e-06 28.0 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG07852.1 - 3.3e-06 26.6 0.0 0.06 12.6 0.1 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 OAG07852.1 - 2.6e-05 24.0 0.0 9.3e-05 22.2 0.0 1.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG07852.1 - 2.7e-05 23.6 0.0 0.042 13.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG07852.1 - 4.9e-05 23.8 0.0 0.017 15.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG07852.1 - 0.0046 16.9 0.2 0.36 10.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF2795 PF11387.8 OAG07852.1 - 0.0065 16.6 0.2 0.044 14.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2795) FAD_binding_2 PF00890.24 OAG07852.1 - 0.01 15.0 0.0 0.021 13.9 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 OAG07852.1 - 0.012 15.8 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 OAG07852.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 OAG07852.1 - 0.043 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAG07852.1 - 0.044 12.5 0.0 0.34 9.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 OAG07852.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Methyltransf_2 PF00891.18 OAG07853.1 - 7.4e-28 97.3 0.0 1.4e-27 96.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain HTH_24 PF13412.6 OAG07853.1 - 0.0011 18.5 0.3 0.003 17.1 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Methyltransf_25 PF13649.6 OAG07853.1 - 0.0049 17.5 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG07853.1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HTH_AsnC-type PF13404.6 OAG07853.1 - 0.028 14.2 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Methyltransf_12 PF08242.12 OAG07853.1 - 0.04 14.7 0.0 0.14 12.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain HTH_28 PF13518.6 OAG07853.1 - 0.057 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CheR PF01739.18 OAG07853.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Zn_clus PF00172.18 OAG07854.1 - 1e-07 32.0 11.1 2.1e-07 31.0 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG07854.1 - 0.014 14.4 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 OAG07855.1 - 1e-46 159.5 0.0 1.4e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07855.1 - 2.5e-08 33.9 7.4 5.5e-08 32.8 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAG07856.1 - 1.4e-09 37.9 0.1 2.2e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG07856.1 - 2.8e-07 30.2 0.2 0.00047 19.7 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 OAG07856.1 - 0.0042 16.6 0.0 0.074 12.5 0.0 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG07856.1 - 0.0054 15.9 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain His_Phos_2 PF00328.22 OAG07857.1 - 3.1e-109 365.9 0.1 4.2e-109 365.4 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OAG07857.1 - 7.7e-35 118.9 0.0 1.7e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OAG07857.1 - 8.2e-05 22.3 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Fungal_trans PF04082.18 OAG07859.1 - 1.8e-09 37.0 0.0 2.6e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG07859.1 - 0.00019 21.5 9.9 0.00038 20.5 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3235 PF11574.8 OAG07859.1 - 0.14 13.0 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Sugar_tr PF00083.24 OAG07860.1 - 1.3e-85 287.9 21.1 1.5e-85 287.8 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07860.1 - 1.3e-26 93.4 32.3 1.8e-19 69.9 8.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 OAG07860.1 - 0.0026 16.6 7.9 0.083 11.7 3.3 2.4 2 0 0 2 2 2 2 POT family PUCC PF03209.15 OAG07860.1 - 0.0046 16.0 17.3 0.015 14.3 1.4 2.9 2 1 1 3 3 3 3 PUCC protein EMP70 PF02990.16 OAG07860.1 - 0.014 14.1 0.2 0.014 14.1 0.2 2.4 2 1 0 2 2 2 0 Endomembrane protein 70 DUF5597 PF18120.1 OAG07861.1 - 2.6e-23 82.6 0.0 4.3e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 OAG07861.1 - 9.1e-11 41.7 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 OAG07861.1 - 5.4e-07 29.5 0.0 8.1e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 OAG07861.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 10 AAA_16 PF13191.6 OAG07862.1 - 1.5e-06 28.7 0.1 4.5e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG07862.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2193 PF09959.9 OAG07862.1 - 0.069 11.6 0.0 0.098 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Nnf1 PF03980.14 OAG07862.1 - 0.12 12.7 0.4 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 Nnf1 ATPase PF06745.13 OAG07862.1 - 0.19 11.1 0.0 0.49 9.7 0.0 1.6 1 0 0 1 1 1 0 KaiC Arf PF00025.21 OAG07863.1 - 6.2e-20 71.4 0.0 1.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG07863.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Carbpep_Y_N PF05388.11 OAG07866.1 - 0.013 16.0 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Utp21 PF04192.12 OAG07868.1 - 1.1e-76 257.4 0.0 1.6e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 OAG07868.1 - 4.6e-18 65.3 0.0 3.9e-06 27.1 0.1 6.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG07868.1 - 3.3e-16 59.4 26.5 0.00031 21.5 0.7 9.7 9 1 0 9 9 9 3 WD domain, G-beta repeat Nup160 PF11715.8 OAG07868.1 - 0.0032 16.2 0.3 0.6 8.7 0.0 3.3 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OAG07868.1 - 0.005 15.4 0.0 0.0081 14.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 OAG07868.1 - 0.0067 15.2 0.0 3.9 6.1 0.1 2.8 2 1 1 3 3 3 2 Nup133 N terminal like PALB2_WD40 PF16756.5 OAG07868.1 - 0.096 11.6 0.0 11 4.8 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 OAG07868.1 - 0.1 11.5 0.2 4.9 6.0 0.0 3.3 3 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG07868.1 - 0.18 11.7 0.2 3.6 7.4 0.0 3.0 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A Meth_synt_2 PF01717.18 OAG07869.1 - 2.2e-12 46.9 0.0 1.8e-09 37.3 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG07869.1 - 0.033 13.7 0.0 0.084 12.4 0.0 1.6 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain DUF383 PF04063.14 OAG07871.1 - 3.2e-66 222.6 0.0 7.2e-66 221.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OAG07871.1 - 6.7e-22 77.1 2.8 1.2e-21 76.3 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) MlaA PF04333.13 OAG07871.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 MlaA lipoprotein MFS_1 PF07690.16 OAG07872.1 - 2.3e-22 79.4 45.1 2.3e-22 79.4 45.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF676 PF05057.14 OAG07875.1 - 4.3e-42 144.1 0.0 3.1e-28 98.8 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.25 OAG07875.1 - 0.011 15.7 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 OAG07875.1 - 0.028 13.7 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Rib_hydrolayse PF02267.17 OAG07877.1 - 0.0052 16.2 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosyl cyclase CMAS PF02353.20 OAG07877.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FoP_duplication PF13865.6 OAG07877.1 - 10 6.8 19.7 35 5.1 19.7 1.9 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF1768 PF08719.11 OAG07878.1 - 6.3e-21 75.3 0.0 9.1e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Rib_hydrolayse PF02267.17 OAG07879.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosyl cyclase DUF1768 PF08719.11 OAG07880.1 - 2.5e-21 76.6 0.0 3.3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.25 OAG07882.1 - 4.1e-13 49.3 0.0 1.1e-12 47.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07882.1 - 9.9e-05 21.7 0.0 0.00089 18.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase VWA_CoxE PF05762.14 OAG07882.1 - 0.0029 17.0 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein APH PF01636.23 OAG07882.1 - 0.0098 15.8 0.1 0.82 9.5 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tom37_C PF11801.8 OAG07882.1 - 0.18 11.7 0.4 0.42 10.6 0.1 1.7 2 0 0 2 2 2 0 Tom37 C-terminal domain Fib_alpha PF08702.10 OAG07883.1 - 0.0077 16.4 0.2 0.32 11.2 0.0 2.5 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family CorA PF01544.18 OAG07883.1 - 0.21 10.9 6.5 0.33 10.2 4.3 2.4 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein MBOAT_2 PF13813.6 OAG07884.1 - 2.3e-16 59.8 2.2 6.9e-16 58.3 1.7 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Actin PF00022.19 OAG07885.1 - 7.2e-91 304.8 0.0 7.3e-90 301.5 0.0 1.9 1 1 0 1 1 1 1 Actin Ribosomal_L50 PF10501.9 OAG07886.1 - 1.5e-13 50.8 0.1 5.2e-13 49.1 0.1 2.0 1 0 0 1 1 1 1 Ribosomal subunit 39S HET PF06985.11 OAG07887.1 - 2.2e-13 50.8 4.7 1.5e-10 41.6 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG07888.1 - 6.2e-33 114.2 0.5 2.8e-32 112.1 1.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4851 PF16143.5 OAG07888.1 - 0.019 14.4 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) HET PF06985.11 OAG07889.1 - 4.3e-22 79.0 0.0 8.7e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MoaF_C PF17409.2 OAG07889.1 - 0.093 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 MoaF C-terminal domain adh_short PF00106.25 OAG07891.1 - 1.5e-34 119.2 0.0 1.9e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG07891.1 - 1e-16 61.2 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG07891.1 - 1.7e-09 37.9 0.1 3e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG07891.1 - 0.0045 16.5 0.1 0.0056 16.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG07891.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG07891.1 - 0.025 14.8 0.0 0.079 13.2 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG07891.1 - 0.065 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 OAG07891.1 - 0.1 11.7 0.1 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG07891.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAT PF02259.23 OAG07897.1 - 4.9e-113 377.9 0.2 4.9e-113 377.9 0.2 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OAG07897.1 - 5.2e-72 242.7 0.1 1.8e-71 240.9 0.1 1.9 2 0 0 2 2 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OAG07897.1 - 4.9e-63 211.8 3.3 8.1e-58 194.9 0.1 6.7 6 2 1 8 8 8 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OAG07897.1 - 2.4e-43 146.6 4.9 1.4e-42 144.1 0.0 3.9 3 1 0 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 OAG07897.1 - 2.3e-16 59.3 0.1 5.7e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 OAG07897.1 - 4.4e-13 49.4 15.4 0.0007 19.9 0.0 10.0 9 2 2 11 11 10 3 HEAT repeats HEAT_EZ PF13513.6 OAG07897.1 - 6.7e-11 42.5 16.5 0.00063 20.2 0.0 10.4 11 1 1 12 12 11 1 HEAT-like repeat HEAT PF02985.22 OAG07897.1 - 7.9e-10 38.1 23.2 0.043 14.1 0.1 11.3 13 0 0 13 13 12 3 HEAT repeat Adaptin_N PF01602.20 OAG07897.1 - 8.7e-05 21.3 2.2 2.4 6.6 0.0 5.6 4 2 0 5 5 5 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OAG07897.1 - 9.2e-05 23.0 0.0 11 6.7 0.0 5.6 5 0 0 5 5 4 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 OAG07897.1 - 0.00042 20.0 0.0 2.9 7.3 0.0 3.7 2 1 1 3 3 3 1 Tti2 family HEAT_PBS PF03130.16 OAG07897.1 - 0.0015 19.0 1.2 24 6.0 0.0 6.2 5 1 0 5 5 4 0 PBS lyase HEAT-like repeat CLASP_N PF12348.8 OAG07897.1 - 0.0037 16.8 0.6 18 4.8 0.0 5.1 5 1 0 5 5 5 0 CLASP N terminal UME PF08064.13 OAG07897.1 - 0.0041 17.0 0.3 8 6.4 0.0 5.2 6 1 0 6 6 5 1 UME (NUC010) domain DUF3730 PF12530.8 OAG07897.1 - 0.018 14.7 0.1 0.42 10.1 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3730) TAF6_C PF07571.13 OAG07897.1 - 0.025 14.9 0.0 4.3 7.7 0.0 4.6 4 1 1 5 5 4 0 TAF6 C-terminal HEAT repeat domain TPR_16 PF13432.6 OAG07897.1 - 0.065 13.9 1.3 1.3 9.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG07897.1 - 0.16 11.7 0.5 14 5.4 0.0 2.8 2 0 0 2 2 2 0 TPR repeat Arm PF00514.23 OAG07897.1 - 2.5 8.3 6.9 8.3 6.6 0.0 4.4 5 0 0 5 5 3 0 Armadillo/beta-catenin-like repeat Lipase_3 PF01764.25 OAG07899.1 - 9e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAG07899.1 - 0.061 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VPS9 PF02204.18 OAG07900.1 - 5e-26 90.9 0.1 1.1e-25 89.8 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAG07900.1 - 0.00061 20.1 0.6 0.003 17.8 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5601) Fungal_TACC PF12709.7 OAG07901.1 - 1.6e-07 31.6 4.0 1.6e-07 31.6 4.0 4.1 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 OAG07901.1 - 1.9e-05 24.2 27.6 0.0038 16.6 10.7 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) FPP PF05911.11 OAG07901.1 - 7.5e-05 21.1 16.5 7.5e-05 21.1 16.5 2.7 1 1 2 3 3 3 1 Filament-like plant protein, long coiled-coil DUF745 PF05335.13 OAG07901.1 - 8.7e-05 22.3 11.7 8.7e-05 22.3 11.7 3.2 2 1 2 4 4 4 1 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 OAG07901.1 - 0.0075 16.4 16.7 0.0075 16.4 16.7 3.6 2 1 0 2 2 2 1 Tropomyosin like Baculo_PEP_C PF04513.12 OAG07901.1 - 0.021 14.9 1.8 17 5.5 0.0 3.8 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 OAG07901.1 - 0.29 10.7 21.3 0.37 10.3 3.8 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit WXG100 PF06013.12 OAG07901.1 - 0.67 10.2 9.9 5.6 7.3 3.3 4.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF5344 PF17279.2 OAG07901.1 - 0.85 10.2 0.0 0.85 10.2 0.0 3.9 3 1 1 4 4 4 0 Family of unknown function (DUF5344) CENP-F_leu_zip PF10473.9 OAG07901.1 - 3.4 7.7 50.9 0.64 10.0 8.0 4.2 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 OAG07901.1 - 3.4 7.4 11.9 3.1 7.6 0.2 3.0 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 OAG07901.1 - 4.5 7.6 24.3 0.42 10.9 7.1 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF16 PF01519.16 OAG07901.1 - 5.5 7.5 22.1 1.7 9.2 1.8 4.2 2 1 2 4 4 4 0 Protein of unknown function DUF16 Y_phosphatase PF00102.27 OAG07902.1 - 6.4e-60 202.6 0.3 2.5e-31 109.1 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 OAG07902.1 - 1.7e-12 47.8 0.0 4.9e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 OAG07902.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 OAG07902.1 - 0.022 14.6 0.5 0.058 13.2 0.5 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain MFS_1 PF07690.16 OAG07903.1 - 3.2e-22 78.9 76.5 2.3e-19 69.6 47.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4808 PF16066.5 OAG07903.1 - 0.095 13.2 1.1 0.16 12.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) Toxin_3 PF00537.18 OAG07905.1 - 0.074 13.3 0.7 0.13 12.5 0.7 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain DAHP_synth_1 PF00793.20 OAG07908.1 - 3.5e-102 341.0 0.0 4.1e-102 340.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Lactamase_B_2 PF12706.7 OAG07910.1 - 3.1e-27 95.4 0.0 2.1e-25 89.4 0.0 2.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG07910.1 - 9.3e-12 45.1 0.0 2.5e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG07910.1 - 0.0057 16.7 3.9 2 8.3 1.8 3.0 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Cyclin PF08613.11 OAG07911.1 - 3.5e-09 37.2 0.0 5.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG07911.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L30_N PF08079.12 OAG07912.1 - 2.4e-24 85.4 18.7 2.4e-24 85.4 18.7 1.9 3 0 0 3 3 3 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OAG07912.1 - 6.1e-19 67.7 3.1 1.3e-18 66.6 3.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e CSRNP_N PF16019.5 OAG07912.1 - 0.044 13.7 4.5 0.067 13.1 4.5 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CFEM PF05730.11 OAG07914.1 - 0.0049 16.9 1.6 0.0049 16.9 1.6 1.8 2 0 0 2 2 2 1 CFEM domain Mitofilin PF09731.9 OAG07914.1 - 1.8 7.3 13.8 2.6 6.8 13.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pkinase PF00069.25 OAG07915.1 - 2.2e-64 217.4 0.0 3.2e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07915.1 - 1.1e-30 106.8 0.0 1.1e-30 106.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAG07915.1 - 0.00024 20.5 0.1 0.00041 19.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAG07915.1 - 0.00039 20.1 0.1 0.00039 20.1 0.1 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OAG07915.1 - 0.0016 18.4 0.0 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG07915.1 - 0.002 17.2 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain CDC45 PF02724.14 OAG07915.1 - 1.5 7.1 4.1 1.9 6.7 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_28 PF02636.17 OAG07916.1 - 2.4e-75 253.5 0.0 3.1e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Senescence PF06911.12 OAG07916.1 - 0.031 14.6 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein PRMT5 PF05185.16 OAG07916.1 - 0.23 11.3 0.0 0.46 10.3 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Got1 PF04178.12 OAG07917.1 - 2e-14 54.0 13.8 2.5e-14 53.6 13.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YL1_C PF08265.11 OAG07918.1 - 1e-16 60.4 0.4 1.9e-16 59.5 0.4 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.10 OAG07919.1 - 8.4e-33 112.2 5.2 9.1e-33 112.1 5.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Biotin_carb_C PF02785.19 OAG07919.1 - 0.021 14.9 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain DASH_Dad1 PF08649.10 OAG07919.1 - 0.031 14.5 3.0 0.041 14.1 3.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 GM_CSF PF01109.17 OAG07919.1 - 0.084 13.0 0.3 0.092 12.9 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Actin PF00022.19 OAG07920.1 - 1.3e-51 175.5 0.0 7.4e-28 97.3 0.0 2.3 2 0 0 2 2 2 2 Actin DUF3040 PF11239.8 OAG07920.1 - 0.12 12.6 0.2 0.36 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Anoctamin PF04547.12 OAG07922.1 - 2.7e-114 382.5 1.6 3.4e-114 382.1 1.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OAG07922.1 - 0.036 13.8 0.1 0.08 12.6 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RRM_1 PF00076.22 OAG07923.1 - 3.6e-15 55.5 0.0 5e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC6 PF05460.13 OAG07923.1 - 1.9 7.7 12.1 3.6 6.8 12.1 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Profilin PF00235.19 OAG07924.1 - 6e-41 139.7 1.1 6.6e-41 139.5 1.1 1.0 1 0 0 1 1 1 1 Profilin HeLo PF14479.6 OAG07925.1 - 1.3e-42 146.0 0.5 2.3e-42 145.2 0.5 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 OAG07925.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Metallophos PF00149.28 OAG07926.1 - 1e-10 42.5 1.6 2.6e-10 41.2 1.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG07926.1 - 4.2e-06 27.0 2.5 6.3e-05 23.2 2.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S11 PF00411.19 OAG07927.1 - 1.4e-46 157.4 1.6 1.8e-46 157.1 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.17 OAG07928.1 - 2.2e-14 53.1 0.0 3.4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase PAP2 PF01569.21 OAG07929.1 - 3.1e-25 88.5 3.1 3.1e-25 88.5 3.1 1.8 2 1 0 2 2 2 1 PAP2 superfamily DUF983 PF06170.12 OAG07929.1 - 3.9 8.0 6.2 19 5.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) EAP30 PF04157.16 OAG07930.1 - 7.2e-64 215.3 0.0 8.1e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family AAR2 PF05282.11 OAG07931.1 - 3.9e-97 325.8 0.2 5.9e-97 325.2 0.2 1.2 1 0 0 1 1 1 1 AAR2 protein DUF4994 PF16385.5 OAG07931.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function zf-LITAF-like PF10601.9 OAG07932.1 - 3e-21 75.5 7.6 4e-21 75.1 7.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ISL3 PF14690.6 OAG07932.1 - 0.13 13.0 3.0 4.9 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 OAG07932.1 - 0.64 10.0 5.2 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Pex14_N PF04695.13 OAG07932.1 - 7.9 7.1 13.5 21 5.7 13.5 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3c_N PF05470.12 OAG07933.1 - 4.8e-176 586.6 21.3 4.8e-176 586.6 21.3 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OAG07933.1 - 5.8e-14 52.5 0.2 3.1e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 PCI domain DUF1385 PF07136.11 OAG07933.1 - 0.0082 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) PP-binding_2 PF14573.6 OAG07933.1 - 0.11 12.7 0.1 2.7 8.3 0.0 2.6 2 0 0 2 2 2 0 Acyl-carrier DNA_pol_phi PF04931.13 OAG07933.1 - 0.73 7.9 26.8 4.9 5.1 0.2 2.4 2 0 0 2 2 2 0 DNA polymerase phi Arg_decarbox_C PF17944.1 OAG07933.1 - 0.77 10.4 3.3 1.2 9.7 0.0 3.2 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension SDA1 PF05285.12 OAG07933.1 - 9.3 5.6 28.0 20 4.5 28.0 1.4 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 OAG07934.1 - 7.1e-51 173.1 0.0 1.8e-50 171.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07934.1 - 4.2e-23 82.0 0.0 4.2e-23 82.0 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 OAG07934.1 - 0.00021 21.3 3.7 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG07934.1 - 0.005 16.4 0.2 0.018 14.6 0.2 1.9 1 1 0 1 1 1 1 RIO1 family K_oxygenase PF13434.6 OAG07935.1 - 9.1e-101 337.4 0.0 1.2e-100 337.0 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG07935.1 - 1.7e-07 30.8 0.0 6.6e-06 25.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ABC_membrane PF00664.23 OAG07936.1 - 1.4e-79 267.6 25.9 4.1e-44 151.3 10.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG07936.1 - 1.5e-69 232.8 0.0 7.5e-34 117.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG07936.1 - 6.9e-12 45.3 0.2 0.00039 19.9 0.7 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG07936.1 - 3.6e-07 30.5 0.1 0.0011 19.2 0.0 3.6 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG07936.1 - 1.7e-06 28.5 1.4 0.021 15.2 0.2 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAG07936.1 - 2.9e-06 26.9 0.1 0.032 14.0 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OAG07936.1 - 9.5e-06 25.0 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 OAG07936.1 - 2.7e-05 24.2 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OAG07936.1 - 6e-05 22.9 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 OAG07936.1 - 8.9e-05 21.5 0.1 0.26 10.1 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 OAG07936.1 - 0.00017 21.5 2.8 0.37 10.5 0.1 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OAG07936.1 - 0.00044 20.4 0.3 0.022 14.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 OAG07936.1 - 0.0044 17.2 4.3 1.3 9.3 0.3 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit YuiB PF14068.6 OAG07936.1 - 0.0046 17.5 0.6 0.027 15.0 0.6 2.4 1 0 0 1 1 1 1 Putative membrane protein AAA_30 PF13604.6 OAG07936.1 - 0.0078 16.0 0.2 2.2 7.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAG07936.1 - 0.0085 15.7 0.4 0.38 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.20 OAG07936.1 - 0.0094 15.9 0.1 6.7 6.6 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.14 OAG07936.1 - 0.011 15.7 0.0 0.37 10.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OAG07936.1 - 0.018 15.4 0.1 8.6 6.8 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OAG07936.1 - 0.024 14.1 0.0 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 OAG07936.1 - 0.029 14.5 0.1 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 OAG07936.1 - 0.033 14.3 0.1 8.3 6.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 OAG07936.1 - 0.042 13.6 0.2 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 OAG07936.1 - 0.052 14.1 0.1 2.2 8.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain CBP_BcsG PF11658.8 OAG07936.1 - 0.1 11.0 1.4 0.2 10.0 1.4 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG AAA_18 PF13238.6 OAG07936.1 - 0.12 12.9 0.1 0.77 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.28 OAG07938.1 - 0 1026.6 0.0 7e-81 272.0 0.0 4.4 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 OAG07938.1 - 3.7e-206 685.2 0.0 6.3e-39 133.9 0.0 6.2 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 OAG07938.1 - 6.5e-61 202.6 8.8 5.4e-10 39.5 0.1 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG07938.1 - 2.9e-16 60.2 0.4 0.012 16.5 0.0 5.1 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 OAG07938.1 - 0.0057 16.5 0.0 4 7.1 0.0 3.9 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain PAP_assoc PF03828.19 OAG07941.1 - 4.8e-10 39.5 0.0 9.4e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG07941.1 - 1.7e-07 31.4 0.0 3.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pam16 PF03656.13 OAG07942.1 - 5.7e-29 100.7 0.1 6.9e-29 100.4 0.1 1.1 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.11 OAG07943.1 - 1.4e-98 330.2 0.0 1.8e-98 329.9 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin RSN1_7TM PF02714.15 OAG07944.1 - 2.5e-74 250.0 17.0 4.9e-74 249.1 17.0 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAG07944.1 - 5e-39 134.3 0.0 7.5e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAG07944.1 - 9.4e-37 126.2 2.5 2.9e-36 124.6 2.5 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport ODV-E18 PF10717.9 OAG07944.1 - 0.015 15.2 1.9 0.13 12.1 0.2 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF1192 PF06698.11 OAG07944.1 - 0.22 11.6 0.2 0.6 10.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Lipoprotein_15 PF03640.15 OAG07945.1 - 0.46 10.1 1.7 0.53 9.9 0.3 1.8 2 0 0 2 2 2 0 Secreted repeat of unknown function Abhydrolase_6 PF12697.7 OAG07947.1 - 1.2e-09 39.2 0.1 1.6e-09 38.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG07947.1 - 2.9e-07 30.4 0.0 4.2e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG07947.1 - 0.00051 19.4 0.1 0.002 17.4 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 OAG07947.1 - 0.033 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Peptidase_S9 PF00326.21 OAG07947.1 - 0.047 13.2 0.0 9 5.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family FANCA_interact PF15751.5 OAG07948.1 - 0.036 14.6 0.6 0.058 13.9 0.6 1.3 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain DegS PF05384.11 OAG07948.1 - 0.055 12.9 2.8 0.078 12.5 2.8 1.3 1 0 0 1 1 1 0 Sensor protein DegS PEP-utilisers_N PF05524.13 OAG07948.1 - 0.32 11.2 2.8 0.52 10.5 2.8 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal FXMRP1_C_core PF12235.8 OAG07950.1 - 0.19 12.4 9.3 0.87 10.2 4.0 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Sugar_tr PF00083.24 OAG07951.1 - 3.7e-80 270.0 29.0 4.2e-80 269.8 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG07951.1 - 6.3e-23 81.3 28.2 1.3e-22 80.2 24.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily GCIP PF13324.6 OAG07952.1 - 8.9e-27 94.3 1.7 2.9e-26 92.6 1.7 1.8 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF5304 PF17230.2 OAG07952.1 - 0.038 14.2 1.0 0.11 12.8 0.0 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5304) CFEM PF05730.11 OAG07955.1 - 7.2e-14 51.6 12.9 1.3e-13 50.8 12.9 1.4 1 0 0 1 1 1 1 CFEM domain E3_binding PF02817.17 OAG07955.1 - 0.077 13.4 0.3 0.29 11.5 0.3 2.1 1 0 0 1 1 1 0 e3 binding domain PRKCSH-like PF12999.7 OAG07956.1 - 2e-44 151.5 10.3 1.8e-25 89.7 2.5 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OAG07956.1 - 9.7e-34 116.3 1.2 1e-32 113.0 0.1 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OAG07956.1 - 1.1e-10 42.4 0.5 1.1e-10 42.4 0.5 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein GOLGA2L5 PF15070.6 OAG07956.1 - 0.032 12.9 5.8 0.18 10.4 0.1 2.3 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Fib_alpha PF08702.10 OAG07956.1 - 0.24 11.6 8.7 3.8 7.7 1.6 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 OAG07956.1 - 0.24 10.7 11.7 0.52 9.6 8.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 OAG07956.1 - 0.5 10.1 14.3 0.62 9.8 0.5 3.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 SPOUT_MTase PF02590.17 OAG07956.1 - 1 9.4 3.3 1.1 9.2 2.2 1.6 1 1 0 1 1 1 0 Predicted SPOUT methyltransferase TPR_MLP1_2 PF07926.12 OAG07956.1 - 1.3 9.1 19.2 2.5 8.2 0.1 3.9 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 OAG07956.1 - 1.3 9.6 15.8 0.12 12.9 2.1 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region Lectin_N PF03954.14 OAG07956.1 - 1.6 8.5 4.2 3 7.6 0.1 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF641 PF04859.12 OAG07956.1 - 1.7 9.0 8.1 0.79 10.1 4.6 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF883 PF05957.13 OAG07956.1 - 2.2 8.9 13.0 20 5.9 0.1 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Fzo_mitofusin PF04799.13 OAG07956.1 - 2.4 7.7 6.6 5.9 6.4 1.7 2.4 2 0 0 2 2 2 0 fzo-like conserved region Prefoldin PF02996.17 OAG07956.1 - 4.1 7.3 13.6 0.62 10.0 0.7 2.9 3 0 0 3 3 3 0 Prefoldin subunit Laminin_II PF06009.12 OAG07956.1 - 4.1 7.4 9.6 0.69 9.9 5.1 1.9 2 1 0 2 2 2 0 Laminin Domain II ATG16 PF08614.11 OAG07956.1 - 5.4 7.2 17.9 7.5 6.7 6.1 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) TEX13 PF15186.6 OAG07956.1 - 5.4 6.7 7.9 1.1 8.9 1.4 2.6 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family Recep_L_domain PF01030.24 OAG07959.1 - 0.0054 16.8 0.2 6.8 6.9 0.0 3.6 2 2 2 4 4 4 3 Receptor L domain Pkinase PF00069.25 OAG07960.1 - 3.5e-36 124.9 0.0 4.4e-35 121.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG07960.1 - 7.1e-25 87.8 0.0 8.9e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG07960.1 - 0.038 13.3 2.3 2.7 7.3 2.4 2.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBCV_basic_adap PF08789.10 OAG07960.1 - 0.079 13.1 0.3 0.15 12.2 0.3 1.4 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain APH PF01636.23 OAG07960.1 - 0.092 12.7 0.3 0.38 10.6 0.3 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family SLAC1 PF03595.17 OAG07961.1 - 6.6e-84 281.9 42.3 7.6e-84 281.7 42.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Lipase_GDSL PF00657.22 OAG07962.1 - 1.4e-07 31.7 0.0 1.8e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAG07962.1 - 3.9e-07 30.6 0.3 5.6e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Oxidored_FMN PF00724.20 OAG07963.1 - 1.3e-95 320.6 0.0 1.5e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OAG07963.1 - 0.0011 18.4 0.1 2.3 7.6 0.0 2.8 2 1 1 3 3 3 2 Xylose isomerase-like TIM barrel COesterase PF00135.28 OAG07965.1 - 1.8e-71 241.6 0.0 2.3e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG07965.1 - 1.7e-06 28.1 0.3 1.6e-05 24.9 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG07965.1 - 0.0063 16.0 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_M35 PF02102.15 OAG07967.1 - 5.1e-89 298.6 23.6 6e-89 298.4 23.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 OAG07967.1 - 2.1e-43 148.4 6.2 2.1e-43 148.4 6.2 1.7 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase Polyoma_coat2 PF00761.20 OAG07967.1 - 0.17 11.6 6.2 0.3 10.8 6.2 1.4 1 0 0 1 1 1 0 Polyomavirus coat protein MFS_1 PF07690.16 OAG07968.1 - 3e-41 141.5 21.9 4.5e-41 140.9 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG07968.1 - 1e-19 70.7 6.1 1e-19 70.7 6.1 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG07968.1 - 4.2e-06 25.5 2.0 6.5e-06 24.8 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3100 PF11299.8 OAG07968.1 - 0.029 13.8 0.2 0.029 13.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3100) DUF4536 PF15055.6 OAG07969.1 - 0.11 12.8 0.0 4.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Podoplanin PF05808.11 OAG07971.1 - 0.003 17.7 0.1 0.005 17.0 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Romo1 PF10247.9 OAG07971.1 - 0.018 15.4 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Gram_pos_anchor PF00746.21 OAG07971.1 - 0.13 12.2 0.6 0.25 11.3 0.6 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PAP1 PF08601.10 OAG07971.1 - 4.6 6.9 11.0 6.6 6.3 11.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PPP4R2 PF09184.11 OAG07972.1 - 0.052 13.1 12.6 0.068 12.8 12.6 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OAG07972.1 - 0.087 12.1 20.3 0.055 12.8 17.7 1.8 2 0 0 2 2 2 0 NOA36 protein zf-NADH-PPase PF09297.11 OAG07972.1 - 0.2 11.3 1.0 0.38 10.4 1.0 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain SDA1 PF05285.12 OAG07972.1 - 0.22 10.9 15.1 0.33 10.3 15.1 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAG07972.1 - 0.38 10.0 12.2 0.59 9.4 12.2 1.3 1 0 0 1 1 1 0 BUD22 Synaptobrevin PF00957.21 OAG07973.1 - 3.8e-13 49.0 1.5 5.7e-13 48.5 1.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAG07973.1 - 2.2e-06 27.6 0.0 4.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec63 PF02889.16 OAG07974.1 - 2.4e-127 423.4 0.0 7e-77 258.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OAG07974.1 - 2.2e-51 174.1 0.0 4.4e-26 91.7 0.4 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 OAG07974.1 - 1.3e-20 74.1 0.0 5e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG07974.1 - 1.5e-15 57.5 0.0 7.2e-07 29.5 0.0 4.0 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAG07974.1 - 2.9e-07 30.8 0.2 0.067 13.5 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OAG07974.1 - 4.3e-07 29.9 0.1 0.0037 17.0 0.2 2.7 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 OAG07974.1 - 2e-06 28.0 1.6 2.8e-06 27.5 0.3 1.9 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA_19 PF13245.6 OAG07974.1 - 3.5e-05 24.2 1.4 0.0024 18.2 0.7 2.8 3 0 0 3 3 3 1 AAA domain DUF2286 PF10051.9 OAG07974.1 - 0.14 11.9 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2286) FAD_binding_3 PF01494.19 OAG07977.1 - 3.9e-16 59.2 0.2 1.3e-07 31.2 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG07977.1 - 0.00027 21.1 0.0 0.00088 19.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG07977.1 - 0.0065 15.7 0.0 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG07977.1 - 0.013 15.1 0.2 0.081 12.5 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase zinc_ribbon_10 PF10058.9 OAG07978.1 - 2.2e-20 72.1 0.0 5.3e-20 70.9 0.1 1.6 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Ima1_N PF09779.9 OAG07978.1 - 0.21 12.4 1.2 1.1 10.1 0.2 2.4 1 1 1 2 2 2 0 Ima1 N-terminal domain Complex1_LYR PF05347.15 OAG07979.1 - 0.00063 19.7 1.0 0.0013 18.8 1.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG07979.1 - 0.0011 19.7 0.1 0.0013 19.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Phage_ABA_S PF18066.1 OAG07979.1 - 0.015 15.9 0.0 0.019 15.7 0.0 1.2 1 0 0 1 1 1 0 Phage ABA sandwich domain RRM_1 PF00076.22 OAG07980.1 - 1.4e-07 31.3 0.0 3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG07980.1 - 9.3e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG07980.1 - 0.00097 19.1 0.0 0.0032 17.5 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif Sterol_MT_C PF08498.10 OAG07981.1 - 7.6e-31 106.2 0.3 1.5e-30 105.3 0.3 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 OAG07981.1 - 1.4e-20 73.7 0.0 2.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG07981.1 - 8.5e-19 68.1 0.0 1.7e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG07981.1 - 5.9e-16 58.6 0.0 8.9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG07981.1 - 3.6e-13 49.4 0.1 5.3e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAG07981.1 - 3.1e-11 43.4 0.0 5.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG07981.1 - 4.2e-09 36.1 0.0 7.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAG07981.1 - 7.2e-09 36.3 0.0 1.9e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 OAG07981.1 - 1.6e-05 23.7 0.0 2.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 OAG07981.1 - 0.0002 21.2 0.0 0.00044 20.0 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OAG07981.1 - 0.00081 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 OAG07981.1 - 0.0013 18.1 0.1 0.0053 16.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 OAG07981.1 - 0.0039 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 OAG07981.1 - 0.0045 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 OAG07981.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG07981.1 - 0.0072 15.8 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 OAG07981.1 - 0.033 14.2 0.4 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 OAG07981.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Transket_pyr PF02779.24 OAG07982.1 - 8.9e-48 162.3 0.0 1.4e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG07982.1 - 4.4e-35 120.3 0.0 1.2e-34 118.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Phage_X PF05155.15 OAG07983.1 - 0.02 15.3 0.0 0.021 15.2 0.0 1.1 1 0 0 1 1 1 0 Phage X family RabGAP-TBC PF00566.18 OAG07986.1 - 5.5e-33 114.4 0.0 2.1e-32 112.6 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Tmemb_cc2 PF10267.9 OAG07986.1 - 0.91 8.6 3.7 1.6 7.8 3.7 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein UQ_con PF00179.26 OAG07988.1 - 5.9e-41 139.4 0.1 7.3e-41 139.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG07988.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG07988.1 - 0.00014 22.1 0.0 0.00018 21.8 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 OAG07988.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 UEV domain YtzH PF14165.6 OAG07988.1 - 0.043 14.2 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 YtzH-like protein BTB PF00651.31 OAG07989.1 - 4.7e-08 33.2 0.1 2e-07 31.2 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain HSF_DNA-bind PF00447.17 OAG07991.1 - 1.9e-29 102.1 0.9 3e-29 101.5 0.9 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding F-box-like PF12937.7 OAG07992.1 - 7.8e-09 35.3 0.1 2.7e-08 33.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG07992.1 - 2.3e-05 24.1 0.1 5.4e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain Pribosyltran PF00156.27 OAG07993.1 - 8.7e-07 28.6 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Inositol_P PF00459.25 OAG07994.1 - 9.5e-71 238.5 0.0 1.1e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family 4HBT PF03061.22 OAG07995.1 - 8e-08 32.5 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Pectate_lyase_3 PF12708.7 OAG07996.1 - 2.6e-91 305.2 13.8 3.4e-77 259.1 2.9 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG07996.1 - 3.7e-07 29.8 1.9 0.0095 15.6 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF202 PF02656.15 OAG07996.1 - 0.0081 16.6 0.6 0.02 15.3 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Lectin_C PF00059.21 OAG07998.1 - 0.017 15.9 0.0 0.025 15.3 0.0 1.2 1 0 0 1 1 1 0 Lectin C-type domain DNA_pol3_finger PF17657.1 OAG08000.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain NmrA PF05368.13 OAG08001.1 - 1.5e-35 122.9 0.0 2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG08001.1 - 4e-25 88.8 0.0 5.4e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG08001.1 - 0.0001 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PdxJ PF03740.13 OAG08001.1 - 0.015 14.4 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ adh_short PF00106.25 OAG08001.1 - 0.062 12.7 0.1 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 OAG08001.1 - 0.072 13.7 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 OAG08001.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Crystall PF00030.19 OAG08002.1 - 0.073 13.3 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Beta/Gamma crystallin TRM PF02005.16 OAG08004.1 - 5.3e-113 378.0 0.0 1.2e-98 330.7 0.0 2.0 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Cons_hypoth95 PF03602.15 OAG08004.1 - 0.019 14.6 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.16 OAG08004.1 - 0.083 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 OAG08004.1 - 0.16 12.7 0.0 0.65 10.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Ferritin_2 PF13668.6 OAG08005.1 - 1.5e-17 64.1 0.0 2.2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ccdc124 PF06244.12 OAG08006.1 - 0.057 14.0 8.1 0.092 13.3 8.1 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Cyt-b5 PF00173.28 OAG08007.1 - 1.3e-12 47.6 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3425 PF11905.8 OAG08009.1 - 6.6e-09 35.8 0.2 1.1e-08 35.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.18 OAG08009.1 - 6.5e-08 32.6 14.3 1.2e-07 31.7 14.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5102 PF17104.5 OAG08009.1 - 0.024 14.7 0.1 0.042 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Pkinase PF00069.25 OAG08011.1 - 4.8e-48 163.8 0.2 1.4e-47 162.3 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08011.1 - 4.5e-27 95.0 0.4 2e-26 92.8 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG08011.1 - 0.00014 21.3 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OAG08011.1 - 0.017 14.7 0.1 0.042 13.4 0.1 1.7 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 OAG08011.1 - 0.091 12.7 0.1 0.091 12.7 0.1 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family Dabb PF07876.12 OAG08012.1 - 5.9e-08 33.2 0.0 1.1e-07 32.4 0.0 1.5 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1691 PF07950.11 OAG08013.1 - 5.5e-34 117.1 4.7 1.1e-28 100.0 3.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF4405 PF14358.6 OAG08013.1 - 0.4 11.3 0.0 0.4 11.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) zf-C2H2_jaz PF12171.8 OAG08014.1 - 1e-05 25.7 0.5 1.5e-05 25.1 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG08014.1 - 0.00045 20.5 0.0 0.00075 19.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OAG08014.1 - 0.0011 19.3 0.3 0.0011 19.3 0.3 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG08014.1 - 0.098 13.0 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 OAG08014.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG08014.1 - 0.3 12.0 0.1 0.3 12.0 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger FYDLN_acid PF09538.10 OAG08014.1 - 1.9 9.2 11.7 1.6 9.4 9.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Sugar_tr PF00083.24 OAG08015.1 - 1.1e-74 252.0 13.6 1.2e-74 251.8 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG08015.1 - 1e-15 57.6 24.9 2.3e-15 56.4 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3767 PF12597.8 OAG08015.1 - 0.08 12.8 0.9 0.24 11.2 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3767) Alpha-amylase PF00128.24 OAG08016.1 - 1.1e-108 363.8 0.0 1.5e-108 363.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OAG08016.1 - 0.0002 21.4 0.0 0.00058 19.9 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OAG08016.1 - 0.0072 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 OAG08016.1 - 0.029 14.7 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) DUF4201 PF13870.6 OAG08019.1 - 0.017 14.8 15.1 0.041 13.6 15.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) JIP_LZII PF16471.5 OAG08019.1 - 0.038 14.2 12.7 0.29 11.4 2.4 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 OAG08019.1 - 0.06 13.9 18.9 0.033 14.7 3.7 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 OAG08019.1 - 0.43 9.9 20.2 3.4 7.0 6.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 OAG08019.1 - 1 8.2 6.9 1.5 7.6 6.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4200 PF13863.6 OAG08019.1 - 1.5 9.2 19.0 0.24 11.8 12.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Fez1 PF06818.15 OAG08019.1 - 1.9 8.9 13.9 3.9 7.9 13.9 1.6 1 0 0 1 1 1 0 Fez1 Csm1_N PF18504.1 OAG08019.1 - 4.3 7.7 13.2 1.4 9.3 1.4 3.5 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF1295 PF06966.12 OAG08020.1 - 3.2e-09 36.7 0.2 4.2e-09 36.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OAG08020.1 - 6.5e-06 25.2 0.1 9.2e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 OAG08020.1 - 0.0051 16.8 0.4 0.0076 16.2 0.4 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OAG08020.1 - 0.042 14.3 0.1 0.09 13.2 0.0 1.7 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Aquarius_N PF16399.5 OAG08022.1 - 0 1083.1 0.0 0 1082.7 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 OAG08022.1 - 1.1e-27 97.0 0.0 1.8e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG08022.1 - 1.6e-22 80.5 0.0 1.2e-21 77.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG08022.1 - 1.4e-07 31.4 0.0 0.0004 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG08022.1 - 9.6e-07 29.2 0.0 2.5e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG08022.1 - 4.3e-06 26.8 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 OAG08022.1 - 0.0014 19.0 0.0 0.0075 16.7 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 OAG08022.1 - 0.0015 18.0 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 OAG08022.1 - 0.0028 18.1 0.0 0.0069 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAG08022.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 OAG08022.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 OAG08022.1 - 0.032 13.8 0.0 0.076 12.5 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 OAG08022.1 - 0.043 14.1 1.6 0.27 11.5 0.2 2.8 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.6 OAG08022.1 - 0.079 12.5 0.3 0.93 9.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 OAG08022.1 - 0.089 12.8 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 OAG08022.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 OAG08022.1 - 0.2 12.0 0.1 0.87 10.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NADH-u_ox-rdase PF10785.9 OAG08023.1 - 5.2e-26 91.1 0.2 7.6e-26 90.6 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 OAG08023.1 - 5.2e-24 84.0 0.2 7.4e-24 83.6 0.2 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit TauD PF02668.16 OAG08024.1 - 3.3e-40 138.6 0.1 5.5e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAG08024.1 - 3.5e-11 43.6 0.1 9.6e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 OAG08024.1 - 0.078 12.1 0.0 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 CsiD SlyX PF04102.12 OAG08024.1 - 0.079 13.6 0.6 0.17 12.5 0.6 1.5 1 0 0 1 1 1 0 SlyX UPF0137 PF03677.13 OAG08024.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TolA_bind_tri PF16331.5 OAG08024.1 - 0.3 11.2 3.7 0.63 10.1 3.7 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation DAO PF01266.24 OAG08027.1 - 2.1e-47 162.4 0.4 2.4e-47 162.2 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG08027.1 - 0.00013 22.2 0.1 0.00051 20.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 OAG08027.1 - 0.00037 19.4 0.1 0.00052 18.9 0.1 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox PF00070.27 OAG08027.1 - 0.00039 20.9 0.0 0.41 11.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG08027.1 - 0.037 13.3 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 OAG08027.1 - 0.043 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 OAG08027.1 - 0.18 11.8 0.1 1 9.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding CRC_subunit PF08624.10 OAG08029.1 - 3.2e-54 183.0 0.0 4.6e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF5050 PF16472.5 OAG08029.1 - 0.034 13.4 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) BNIP2 PF12496.8 OAG08029.1 - 0.11 12.9 1.9 0.8 10.1 0.3 2.6 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 7tm_2 PF00002.24 OAG08030.1 - 0.0023 17.3 10.5 0.0023 17.3 10.5 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Haemocyan_bet_s PF14830.6 OAG08030.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Haemocyanin beta-sandwich Glycophorin_A PF01102.18 OAG08030.1 - 0.14 12.4 1.0 7.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Glycophorin A HET PF06985.11 OAG08032.1 - 0.34 11.2 1.8 0.58 10.5 1.8 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Pox_F17 PF04767.12 OAG08033.1 - 0.14 12.6 1.5 0.16 12.5 1.5 1.2 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein ETF_QO PF05187.13 OAG08035.1 - 1e-48 163.8 0.5 1.7e-48 163.1 0.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 OAG08035.1 - 1.1e-06 28.5 0.6 0.00041 20.0 0.2 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG08035.1 - 4.3e-06 26.9 0.0 1.5e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG08035.1 - 4.3e-06 26.1 0.3 0.0035 16.5 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG08035.1 - 2e-05 24.0 0.0 4.4e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG08035.1 - 0.00033 20.0 0.0 0.00053 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG08035.1 - 0.00041 19.2 0.2 0.00064 18.5 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 OAG08035.1 - 0.00056 19.2 0.1 0.0013 18.0 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OAG08035.1 - 0.0013 19.2 0.2 2.8 8.6 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG08035.1 - 0.0021 17.4 0.2 0.0031 16.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG08035.1 - 0.0045 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG08035.1 - 0.006 16.6 0.1 0.013 15.5 0.2 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.7 OAG08035.1 - 0.031 14.8 0.8 0.09 13.4 0.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 OAG08035.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 OAG08035.1 - 0.073 11.9 0.1 0.26 10.1 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 OAG08035.1 - 0.12 11.4 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG08035.1 - 0.16 11.0 0.2 0.22 10.5 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RRM_1 PF00076.22 OAG08036.1 - 3.8e-12 45.9 0.0 9.2e-12 44.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG08036.1 - 0.047 13.5 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Beta-lactamase PF00144.24 OAG08038.1 - 8.7e-20 71.2 0.0 1.4e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Chorion_3 PF05387.11 OAG08041.1 - 1.1 8.9 14.3 0.11 12.2 8.6 1.9 2 0 0 2 2 2 0 Chorion family 3 Pectate_lyase PF03211.13 OAG08043.1 - 5e-75 251.5 6.8 6.4e-75 251.2 6.8 1.2 1 0 0 1 1 1 1 Pectate lyase Amidohydro_1 PF01979.20 OAG08044.1 - 1.5e-72 244.8 0.0 1.9e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG08044.1 - 2e-09 37.5 0.5 2.4e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OAG08044.1 - 0.047 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Actin PF00022.19 OAG08045.1 - 8.5e-21 74.0 0.0 4.6e-17 61.7 0.0 2.8 3 0 0 3 3 3 2 Actin Alb1 PF09135.11 OAG08045.1 - 0.037 14.9 0.8 0.19 12.6 0.0 2.2 2 0 0 2 2 2 0 Alb1 cNMP_binding PF00027.29 OAG08046.1 - 1.4e-28 98.8 0.1 1.5e-15 57.0 0.0 5.5 4 1 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 OAG08046.1 - 2.7e-16 60.4 9.6 9.7e-16 58.6 6.2 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase SOG2 PF10428.9 OAG08046.1 - 0.085 12.0 2.4 0.16 11.1 2.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_65N PF03636.15 OAG08047.1 - 2.3e-34 119.0 0.0 4.3e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 OAG08047.1 - 5.6e-31 107.7 0.5 1.6e-28 99.6 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain F5_F8_type_C PF00754.25 OAG08047.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 F5/8 type C domain GDC-P PF02347.16 OAG08048.1 - 4.2e-173 576.1 0.0 1.4e-160 534.8 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 OAG08048.1 - 3e-05 23.5 0.1 6.2e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAG08048.1 - 3.1e-05 23.1 0.0 0.0005 19.1 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG08048.1 - 0.043 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.22 OAG08050.1 - 1.8e-11 44.9 0.1 6.6e-11 43.1 0.1 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG08050.1 - 0.0053 16.8 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain UCH PF00443.29 OAG08051.1 - 4.8e-33 114.7 0.0 6.4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG08051.1 - 5.7e-10 39.3 2.4 1.3e-08 34.8 2.4 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L9_N PF01281.19 OAG08052.1 - 7.9e-08 31.7 0.0 1.9e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 OAG08052.1 - 0.0032 17.9 0.1 0.015 15.8 0.1 2.2 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain F_bP_aldolase PF01116.20 OAG08053.1 - 1.3e-95 320.1 0.0 1.4e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Epimerase PF01370.21 OAG08055.1 - 1.1e-11 44.7 0.1 0.00014 21.5 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG08055.1 - 1.2e-08 35.1 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG08055.1 - 2.3e-06 26.9 0.0 0.039 13.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG08055.1 - 8.4e-05 23.0 0.0 0.00022 21.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 OAG08055.1 - 0.00017 21.2 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG08055.1 - 0.001 18.6 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG08055.1 - 0.012 14.8 0.0 0.034 13.3 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein TrkA_N PF02254.18 OAG08055.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OAG08055.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 OAG08055.1 - 0.076 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short_C2 PF13561.6 OAG08056.1 - 7.9e-49 166.3 7.5 1.4e-45 155.6 7.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG08056.1 - 4e-43 147.1 4.5 5.2e-43 146.8 4.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG08056.1 - 2.3e-15 57.0 1.1 4e-15 56.2 1.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG08056.1 - 0.0044 16.9 1.1 0.0072 16.2 1.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG08056.1 - 0.021 14.2 0.4 0.034 13.5 0.4 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG08056.1 - 0.025 14.8 0.1 0.042 14.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG08056.1 - 0.026 14.6 0.1 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 OAG08056.1 - 0.038 14.1 2.4 0.07 13.2 2.3 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 OAG08056.1 - 2.8 7.9 8.3 3.2 7.7 4.5 2.7 2 2 1 3 3 3 0 Zinc-binding dehydrogenase TFR_dimer PF04253.15 OAG08057.1 - 3.4e-29 101.4 0.0 6.5e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG08057.1 - 5.4e-19 68.7 0.0 9.6e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG08057.1 - 6.3e-13 48.6 0.2 3.6e-12 46.1 0.1 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 OAG08057.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 OAG08057.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Nicastrin p450 PF00067.22 OAG08058.1 - 1.8e-75 254.5 0.0 2.1e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pectinesterase PF01095.19 OAG08059.1 - 8.4e-30 103.5 1.9 3.9e-26 91.5 0.8 2.1 2 0 0 2 2 2 2 Pectinesterase Paf67 PF10255.9 OAG08060.1 - 1.7e-157 524.6 0.0 2e-157 524.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 OAG08060.1 - 0.022 14.8 0.3 0.15 12.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2046 PF09755.9 OAG08061.1 - 0.00092 18.5 0.1 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) SlyX PF04102.12 OAG08061.1 - 0.02 15.5 1.5 1.3 9.6 0.6 2.5 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 OAG08061.1 - 0.056 13.2 0.5 0.52 10.1 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator GreA_GreB_N PF03449.15 OAG08061.1 - 0.084 13.0 1.4 0.084 13.0 1.4 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal ZapB PF06005.12 OAG08061.1 - 0.15 12.6 3.1 0.24 11.8 0.6 2.1 2 0 0 2 2 2 0 Cell division protein ZapB CASP_C PF08172.12 OAG08061.1 - 0.15 11.4 2.1 10 5.4 0.0 2.7 3 0 0 3 3 3 0 CASP C terminal Bap31_Bap29_C PF18035.1 OAG08061.1 - 0.62 10.1 3.6 0.78 9.8 0.8 2.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain ATG16 PF08614.11 OAG08061.1 - 1.2 9.4 14.4 0.63 10.2 7.3 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.12 OAG08061.1 - 8.9 6.3 7.7 3.3 7.7 3.9 2.3 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat DbpA PF03880.15 OAG08063.1 - 0.0046 16.9 3.5 0.022 14.8 0.0 2.5 2 0 0 2 2 2 1 DbpA RNA binding domain COX14 PF14880.6 OAG08065.1 - 1.3e-17 63.3 0.4 1.3e-17 63.3 0.4 2.3 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF5084 PF16894.5 OAG08065.1 - 0.16 12.4 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) HemY_N PF07219.13 OAG08065.1 - 0.32 11.2 7.6 0.54 10.5 0.3 2.4 2 0 0 2 2 2 0 HemY protein N-terminus DUF2458 PF10454.9 OAG08066.1 - 7.4e-44 149.4 0.0 9.3e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) MRP-S27 PF10037.9 OAG08066.1 - 0.096 11.5 0.2 0.15 10.9 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF3826 PF12875.7 OAG08066.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) F-box-like_2 PF13013.6 OAG08068.1 - 0.0046 16.9 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain PBP1_TM PF14812.6 OAG08068.1 - 0.099 13.0 0.1 0.099 13.0 0.1 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4360 PF14273.6 OAG08069.1 - 0.069 13.0 0.1 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4360) MFS_1 PF07690.16 OAG08070.1 - 1.2e-28 100.1 24.1 1.2e-28 100.1 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG08070.1 - 8.5e-09 34.8 6.6 1.9e-08 33.6 6.6 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG08070.1 - 2.4 6.9 12.6 0.061 12.2 4.1 2.2 2 0 0 2 2 2 0 MFS_1 like family HET PF06985.11 OAG08071.1 - 3.9e-24 85.7 0.1 1e-23 84.3 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Vps35 PF03635.17 OAG08072.1 - 0 1036.9 5.2 0 1036.7 5.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MOR2-PAG1_N PF14222.6 OAG08072.1 - 0.0039 16.2 0.6 0.34 9.8 0.0 2.3 2 0 0 2 2 2 2 Cell morphogenesis N-terminal Pro_3_hydrox_C PF05373.11 OAG08072.1 - 0.014 15.5 0.3 6.2 7.0 0.0 3.2 3 0 0 3 3 3 0 L-proline 3-hydroxylase, C-terminal DUF4746 PF15928.5 OAG08072.1 - 0.45 9.9 9.6 0.79 9.1 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sugar_tr PF00083.24 OAG08073.1 - 6.6e-100 335.1 26.1 7.6e-100 334.9 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG08073.1 - 5e-27 94.7 30.4 5e-27 94.7 30.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SR-25 PF10500.9 OAG08074.1 - 0.73 9.4 8.5 1 8.9 8.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MAP65_ASE1 PF03999.12 OAG08074.1 - 4.6 5.8 11.4 5.5 5.6 11.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RAP1 PF07218.11 OAG08074.1 - 9 4.4 8.2 9.5 4.4 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BTB PF00651.31 OAG08075.1 - 0.00018 21.7 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Trypsin PF00089.26 OAG08076.1 - 1.7e-62 211.2 4.3 2.1e-62 210.9 4.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OAG08076.1 - 2.3e-05 25.3 3.7 5.6e-05 24.1 3.7 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Inhibitor_I66 PF16850.5 OAG08077.1 - 5e-05 23.2 0.0 0.0004 20.3 0.0 1.9 1 1 1 2 2 2 1 Peptidase inhibitor I66 DUF4537 PF15057.6 OAG08077.1 - 0.06 13.4 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) B277 PF17623.2 OAG08078.1 - 0.81 8.7 5.1 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function Peptidase_M28 PF04389.17 OAG08079.1 - 1.2e-31 109.9 0.0 1.7e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 MaoC_dehydratas PF01575.19 OAG08080.1 - 3.7e-23 81.4 0.0 8.6e-23 80.2 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAG08080.1 - 4.6e-07 30.0 0.0 1.3e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Pkinase PF00069.25 OAG08081.1 - 1.9e-68 230.7 0.0 2.5e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08081.1 - 1.8e-30 106.1 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAG08081.1 - 1.1e-12 48.5 1.4 2.9e-12 47.1 0.1 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAG08081.1 - 1e-08 34.9 0.1 4.1e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 OAG08081.1 - 2.8e-07 30.8 0.0 9.6e-05 22.6 0.0 2.6 2 0 0 2 2 2 1 C2 domain FTA2 PF13095.6 OAG08081.1 - 0.0018 18.0 0.2 0.4 10.3 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OAG08081.1 - 0.0024 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG08081.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG08081.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E3_15_3 PF03307.14 OAG08081.1 - 0.091 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region OFCC1 PF15680.5 OAG08081.1 - 0.095 13.3 0.5 0.22 12.1 0.5 1.5 1 0 0 1 1 1 0 Orofacial cleft 1 candidate gene 1 protein PAP1 PF08601.10 OAG08082.1 - 0.27 10.9 0.0 0.38 10.4 0.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 CBFD_NFYB_HMF PF00808.23 OAG08083.1 - 9.1e-18 64.3 0.7 1.9e-17 63.3 0.7 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG08083.1 - 1.7e-05 25.2 0.7 0.00013 22.4 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Alpha-mann_mid PF09261.11 OAG08083.1 - 0.015 15.5 0.7 0.021 15.0 0.5 1.4 1 1 0 1 1 1 0 Alpha mannosidase middle domain TFIID-31kDa PF02291.15 OAG08083.1 - 0.066 13.3 0.5 0.52 10.4 0.0 1.9 1 1 1 2 2 2 0 Transcription initiation factor IID, 31kD subunit EF-hand_13 PF17958.1 OAG08083.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 EF-hand domain Bromo_TP PF07524.13 OAG08083.1 - 0.085 12.9 0.2 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 Bromodomain associated Spidroin_MaSp PF11260.8 OAG08083.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 Major ampullate spidroin 1 and 2 Snf7 PF03357.21 OAG08084.1 - 2.7e-09 36.9 11.8 2.9e-09 36.8 11.3 1.3 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 OAG08084.1 - 0.025 14.5 1.2 0.033 14.1 1.2 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway CPSase_L_D3 PF02787.19 OAG08084.1 - 0.063 13.6 1.2 0.78 10.1 0.6 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain adh_short PF00106.25 OAG08085.1 - 4.4e-42 143.7 0.3 5.3e-42 143.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG08085.1 - 3.7e-32 111.8 0.5 4.2e-32 111.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG08085.1 - 8.9e-15 55.1 0.8 1.5e-14 54.3 0.8 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG08085.1 - 6.5e-06 26.1 1.4 9.4e-06 25.6 1.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG08085.1 - 0.0014 18.2 0.2 0.0022 17.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAG08085.1 - 0.081 13.2 0.5 0.17 12.1 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain DUF1776 PF08643.10 OAG08085.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ala_racemase_N PF01168.20 OAG08086.1 - 2.1e-26 92.9 0.0 2.6e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Asp_Glu_race PF01177.22 OAG08088.1 - 2.8e-13 50.2 0.1 3.1e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase TANGO2 PF05742.12 OAG08091.1 - 2.4e-76 257.2 0.0 2.7e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 FANCL_C PF11793.8 OAG08092.1 - 3.4e-06 27.1 2.0 6.1e-06 26.3 2.0 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 OAG08092.1 - 1.9e-05 24.6 6.0 3.7e-05 23.7 6.0 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OAG08092.1 - 0.19 12.1 6.9 0.39 11.1 6.9 1.5 1 1 0 1 1 1 0 Ring finger domain zf-C2HC PF01530.18 OAG08096.1 - 0.0055 16.9 6.3 0.032 14.4 6.3 2.1 1 1 0 1 1 1 1 Zinc finger, C2HC type PE_PPE_C PF12484.8 OAG08097.1 - 0.082 13.8 6.6 0.74 10.8 2.0 2.2 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal OppC_N PF12911.7 OAG08098.1 - 0.14 12.2 7.7 15 5.7 0.0 3.5 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Homoserine_dh PF00742.19 OAG08100.1 - 6.7e-52 175.9 0.0 8.6e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OAG08100.1 - 1.6e-13 51.3 0.0 3.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.6 OAG08101.1 - 1.5e-25 89.3 20.1 1.5e-25 89.3 20.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) CUE PF02845.16 OAG08103.1 - 1.6e-10 40.5 0.0 2.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Speriolin_N PF15058.6 OAG08104.1 - 0.14 12.2 2.1 0.28 11.2 2.1 1.5 1 0 0 1 1 1 0 Speriolin N terminus Hydrolase_6 PF13344.6 OAG08105.1 - 2.5e-22 78.9 0.0 5.9e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG08105.1 - 3.4e-18 65.5 0.0 9.8e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG08105.1 - 0.044 14.1 0.1 2 8.7 0.0 2.6 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG08105.1 - 0.095 12.8 0.0 0.74 9.9 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase BetaGal_dom3 PF13363.6 OAG08105.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 PGP_phosphatase PF09419.10 OAG08105.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Aldo_ket_red PF00248.21 OAG08106.1 - 1.1e-48 166.0 0.0 3.6e-48 164.3 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 OAG08107.1 - 0.00056 19.7 1.1 0.00056 19.7 1.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG08107.1 - 0.89 9.5 3.4 0.47 10.4 0.1 2.3 2 0 0 2 2 2 0 F-box domain PFK PF00365.20 OAG08108.1 - 4.6e-187 620.1 2.7 4.8e-105 350.9 1.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 OAG08108.1 - 0.05 13.2 1.6 0.13 11.9 0.1 2.5 4 0 0 4 4 4 0 Diacylglycerol kinase catalytic domain Rdx PF10262.9 OAG08108.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Rdx family Ndc80_HEC PF03801.13 OAG08109.1 - 1.6e-57 193.4 0.4 3.1e-57 192.5 0.4 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family KASH_CCD PF14662.6 OAG08109.1 - 0.0028 17.5 19.0 0.0028 17.5 19.0 2.4 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH WASH_WAHD PF11945.8 OAG08109.1 - 0.086 12.3 11.9 0.12 11.9 1.1 3.5 3 1 1 4 4 4 0 WAHD domain of WASH complex NPV_P10 PF05531.12 OAG08109.1 - 0.36 11.3 15.9 4.1 8.0 0.6 4.9 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 OAG08109.1 - 2.2 8.8 44.8 0.11 13.0 10.2 5.3 4 2 0 4 4 4 0 Cell division protein ZapB FliJ PF02050.16 OAG08109.1 - 2.6 8.3 36.6 0.022 15.0 5.0 4.6 3 1 2 5 5 5 0 Flagellar FliJ protein Fib_alpha PF08702.10 OAG08109.1 - 2.9 8.1 24.2 2.1 8.5 5.6 3.9 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family AKNA PF12443.8 OAG08109.1 - 3.2 8.5 15.0 0.44 11.2 0.5 4.2 3 1 0 3 3 3 0 AT-hook-containing transcription factor Phage_GP20 PF06810.11 OAG08109.1 - 3.7 7.3 31.3 1.4 8.7 2.8 3.6 3 1 1 4 4 4 0 Phage minor structural protein GP20 TRAF_BIRC3_bd PF16673.5 OAG08109.1 - 6.3 6.7 9.8 1.1 9.0 1.2 3.9 2 2 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF4988 PF16378.5 OAG08109.1 - 7.5 6.2 7.7 13 5.4 0.3 3.7 3 1 1 4 4 4 0 Domain of unknown function DHR10 PF18595.1 OAG08109.1 - 8.9 6.4 47.5 0.83 9.7 3.3 4.2 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain TFIIB PF00382.19 OAG08112.1 - 1.1e-26 92.7 0.1 1.2e-16 60.5 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OAG08112.1 - 5.1e-12 45.1 1.7 1.2e-11 44.0 1.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 OAG08112.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain ATP_sub_h PF10775.9 OAG08113.1 - 2.6e-27 94.6 1.3 3.7e-27 94.1 1.3 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h DUF1765 PF08578.10 OAG08114.1 - 6.2e-42 143.0 7.1 1.1e-41 142.2 7.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) DUF2063 PF09836.9 OAG08114.1 - 0.018 15.3 0.1 0.051 13.8 0.1 1.8 1 0 0 1 1 1 0 Putative DNA-binding domain Zn_clus PF00172.18 OAG08115.1 - 2.6e-08 33.8 10.8 6.4e-08 32.6 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG08115.1 - 0.00065 18.6 1.2 0.016 14.0 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF3445 PF11927.8 OAG08116.1 - 4.7e-71 239.0 0.0 6e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ODAPH PF15848.5 OAG08117.1 - 0.063 13.7 0.6 0.18 12.3 0.2 1.9 1 1 1 2 2 2 0 Odontogenesis associated phosphoprotein BTB PF00651.31 OAG08119.1 - 0.0031 17.7 0.0 0.0092 16.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Tfb2 PF03849.14 OAG08121.1 - 5.8e-128 426.8 0.0 7.2e-128 426.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OAG08121.1 - 2.6e-20 72.6 0.9 6.8e-20 71.3 0.9 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OAG08121.1 - 0.00031 20.9 0.0 0.0033 17.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain 4HBT PF03061.22 OAG08122.1 - 2.1e-15 56.8 0.0 2.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAG08122.1 - 0.084 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) TIMELESS PF04821.14 OAG08124.1 - 7.2e-80 268.2 0.0 2e-79 266.7 0.0 1.8 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 OAG08124.1 - 3.4e-29 102.4 8.0 3.4e-29 102.4 8.0 4.4 2 1 1 3 3 3 1 Timeless protein C terminal region 3HCDH_N PF02737.18 OAG08125.1 - 1.8e-54 184.4 0.5 2.4e-54 184.0 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG08125.1 - 6.5e-34 116.4 0.0 1.3e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 OAG08125.1 - 0.0014 18.9 0.1 0.0025 18.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OAG08125.1 - 0.0036 17.5 0.2 0.0092 16.2 0.2 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FeoC PF09012.10 OAG08125.1 - 0.0071 16.4 0.0 3.5 7.8 0.0 2.9 3 0 0 3 3 3 1 FeoC like transcriptional regulator 2-Hacid_dh_C PF02826.19 OAG08125.1 - 0.017 14.5 0.5 0.045 13.1 0.4 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAG08125.1 - 0.031 14.8 0.6 0.079 13.6 0.4 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IL6 PF00489.17 OAG08125.1 - 0.034 13.7 0.1 0.083 12.5 0.1 1.6 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family UDPG_MGDP_dh_N PF03721.14 OAG08125.1 - 0.038 13.6 0.0 0.082 12.5 0.0 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 OAG08125.1 - 0.079 12.5 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TB2_DP1_HVA22 PF03134.19 OAG08126.1 - 5.6e-20 71.1 5.7 9.7e-20 70.3 5.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.12 OAG08127.1 - 1.4e-84 281.7 0.0 1.9e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 p450 PF00067.22 OAG08128.1 - 7.5e-71 239.2 0.1 8.7e-71 239.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 BPL_N PF09825.9 OAG08129.1 - 1.8e-146 488.0 0.0 2.4e-146 487.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 OAG08129.1 - 9.1e-23 80.6 0.0 1.6e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ThuA PF06283.11 OAG08129.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Trehalose utilisation Glyco_hydro_42M PF08532.10 OAG08129.1 - 0.062 12.8 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain CHCH PF06747.13 OAG08130.1 - 0.034 14.3 1.7 0.068 13.3 1.7 1.5 1 0 0 1 1 1 0 CHCH domain MFS_1 PF07690.16 OAG08131.1 - 3.9e-35 121.4 25.7 6e-35 120.8 25.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4925 PF16272.5 OAG08132.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4925) DUF3112 PF11309.8 OAG08133.1 - 7.5e-11 41.9 3.0 3e-09 36.6 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) Aldedh PF00171.22 OAG08134.1 - 2.5e-157 524.1 1.0 2.9e-157 523.9 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Vps54 PF07928.12 OAG08134.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Vps54-like protein Wtap PF17098.5 OAG08134.1 - 0.25 11.3 0.0 0.44 10.5 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family GMC_oxred_N PF00732.19 OAG08135.1 - 6.6e-49 166.9 0.0 1.1e-48 166.2 0.0 1.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG08135.1 - 1.1e-37 129.7 0.0 1.7e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG08135.1 - 2.4e-06 26.9 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG08135.1 - 5.5e-05 23.6 0.3 0.13 12.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG08135.1 - 6.5e-05 23.1 0.0 0.00019 21.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG08135.1 - 0.00012 21.8 0.0 0.003 17.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG08135.1 - 0.00025 20.3 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG08135.1 - 0.0015 17.9 0.0 0.02 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG08135.1 - 0.013 14.8 0.0 0.049 12.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 OAG08135.1 - 0.02 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 OAG08135.1 - 0.025 14.0 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG08135.1 - 0.2 10.3 0.0 0.44 9.2 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein DEAD PF00270.29 OAG08136.1 - 1.4e-49 168.2 0.0 1e-48 165.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG08136.1 - 1.6e-30 105.7 0.0 5.4e-30 104.0 0.0 1.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG08136.1 - 0.00018 21.5 0.0 0.00061 19.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 OAG08136.1 - 0.0058 16.5 0.2 0.011 15.6 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5335) UTP25 PF06862.12 OAG08136.1 - 0.012 14.4 0.1 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C_2 PF13307.6 OAG08136.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.6 OAG08136.1 - 0.03 14.7 0.0 8.5 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain PAS_10 PF13596.6 OAG08136.1 - 0.075 13.6 0.4 0.4 11.3 0.1 2.2 2 0 0 2 2 2 0 PAS domain REC1 PF18501.1 OAG08136.1 - 0.13 12.2 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 Alpha helical recognition lobe domain Phos_pyr_kin PF08543.12 OAG08138.1 - 5.9e-85 284.6 1.8 8.2e-85 284.1 1.8 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 OAG08138.1 - 2.4e-50 171.3 0.2 3.2e-50 170.9 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 OAG08138.1 - 1.3e-07 31.2 0.0 2.2e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF561 PF04481.12 OAG08138.1 - 0.071 12.3 0.1 0.17 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF561) B12-binding PF02310.19 OAG08138.1 - 0.084 12.9 0.1 14 5.8 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain Rad9 PF04139.13 OAG08140.1 - 7.9e-48 163.1 0.0 9.6e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 IHHNV_capsid PF16530.5 OAG08140.1 - 0.14 11.3 0.2 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid PWWP PF00855.17 OAG08141.1 - 0.004 17.5 0.0 0.0085 16.5 0.0 1.6 1 0 0 1 1 1 1 PWWP domain Peptidase_S24 PF00717.23 OAG08142.1 - 3e-07 30.3 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HMG_box PF00505.19 OAG08143.1 - 2.9e-25 88.5 4.5 5.4e-25 87.6 4.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG08143.1 - 2.3e-19 69.7 3.3 2.3e-19 69.7 3.3 1.6 1 1 1 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 OAG08143.1 - 0.0055 17.2 0.1 0.0055 17.2 0.1 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 OAG08143.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain HMG_box_5 PF14887.6 OAG08143.1 - 1.3 9.1 7.5 0.12 12.3 2.7 1.8 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CENP-H PF05837.12 OAG08144.1 - 3.2e-28 98.4 3.0 3.2e-28 98.4 3.0 2.0 2 0 0 2 2 2 1 Centromere protein H (CENP-H) ATG11 PF10377.9 OAG08145.1 - 1.8e-42 144.4 0.1 1.8e-42 144.4 0.1 3.6 4 1 1 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 OAG08145.1 - 1.6e-05 24.2 4.1 0.0001 21.6 1.7 5.8 4 2 1 5 5 5 2 Autophagy protein Apg17 TssC PF17541.2 OAG08145.1 - 0.0082 15.0 0.0 0.0082 15.0 0.0 2.8 2 1 2 4 4 4 1 Type VI secretion system, TssC, VipB DUF4472 PF14739.6 OAG08145.1 - 0.015 16.0 11.9 0.015 16.0 11.9 6.4 5 1 1 6 6 6 0 Domain of unknown function (DUF4472) Ribosomal_S8 PF00410.19 OAG08145.1 - 0.023 14.6 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S8 Inhibitor_I53 PF11714.8 OAG08145.1 - 0.43 10.8 2.5 0.43 10.8 0.2 2.2 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Tnp_22_trimer PF17489.2 OAG08145.1 - 1.6 8.8 6.0 2.3 8.2 3.1 2.9 2 0 0 2 2 2 0 L1 transposable element trimerization domain DUF3584 PF12128.8 OAG08145.1 - 5.1 4.5 59.2 0.16 9.5 51.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) RNase_E_G PF10150.9 OAG08146.1 - 0.0032 16.9 1.4 0.0038 16.7 1.4 1.1 1 0 0 1 1 1 1 Ribonuclease E/G family Seryl_tRNA_N PF02403.22 OAG08146.1 - 0.043 14.0 1.5 0.52 10.6 0.1 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 OAG08146.1 - 0.062 12.7 1.4 0.088 12.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mst1_SARAH PF11629.8 OAG08146.1 - 0.11 12.6 1.8 0.79 9.9 0.1 2.7 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 OEP PF02321.18 OAG08146.1 - 0.91 9.3 8.1 2 8.2 0.6 2.4 2 1 0 2 2 2 0 Outer membrane efflux protein Fib_alpha PF08702.10 OAG08146.1 - 1.5 9.0 4.0 0.87 9.8 0.9 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family IBN_N PF03810.19 OAG08147.1 - 1.7e-17 63.1 0.5 6.5e-14 51.6 0.0 3.4 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.10 OAG08147.1 - 1.2e-07 30.9 5.4 1.6e-07 30.5 0.4 2.6 2 1 0 2 2 2 1 Cse1 RTP1_C1 PF10363.9 OAG08147.1 - 0.018 15.3 0.2 0.44 10.7 0.1 3.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 TcdB_N PF12918.7 OAG08147.1 - 0.04 14.2 0.1 0.15 12.3 0.1 2.0 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Xpo1 PF08389.12 OAG08147.1 - 0.056 13.5 4.8 1.1 9.3 0.0 4.7 5 0 0 5 5 5 0 Exportin 1-like protein HEAT_EZ PF13513.6 OAG08147.1 - 0.11 13.1 4.1 37 5.0 0.7 5.7 6 1 0 6 6 6 0 HEAT-like repeat SapB_2 PF03489.17 OAG08147.1 - 3.9 7.7 5.1 15 5.8 0.1 4.1 4 0 0 4 4 4 0 Saposin-like type B, region 2 DSHCT PF08148.12 OAG08149.1 - 8.9e-52 175.1 0.6 4.8e-51 172.7 0.7 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain Ski2_N PF17911.1 OAG08149.1 - 2.4e-41 140.7 0.0 4.3e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 OAG08149.1 - 4.6e-21 75.9 0.6 7.5e-21 75.3 0.6 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 OAG08149.1 - 3.2e-17 62.8 0.0 7.8e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG08149.1 - 1.6e-06 28.4 0.0 5.9e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG08149.1 - 7.5e-05 22.8 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Swi3 PF07962.12 OAG08150.1 - 4.6e-32 109.8 0.3 7.2e-32 109.2 0.3 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 efThoc1 PF11957.8 OAG08151.1 - 1.7e-110 370.1 0.0 2.1e-110 369.7 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor DUF1217 PF06748.12 OAG08151.1 - 0.067 13.2 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) Homeodomain PF00046.29 OAG08152.1 - 2.5e-17 62.5 3.5 4.8e-17 61.5 3.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG08152.1 - 0.024 14.5 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain PUL PF08324.11 OAG08153.1 - 0.074 12.3 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 PUL domain MIF4G PF02854.19 OAG08157.1 - 3.1e-50 170.8 0.2 3.1e-50 170.8 0.2 2.8 3 0 0 3 3 3 1 MIF4G domain eIF_4G1 PF12152.8 OAG08157.1 - 1.4e-17 63.6 0.2 1.4e-17 63.6 0.2 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 Chlorosome_CsmC PF11098.8 OAG08158.1 - 0.65 10.0 10.1 1.5 8.8 10.1 1.6 1 1 0 1 1 1 0 Chlorosome envelope protein C Ferric_reduct PF01794.19 OAG08159.1 - 1.2e-18 67.4 12.1 1.2e-18 67.4 12.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG08159.1 - 1.3e-08 35.1 0.0 0.002 18.3 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG08159.1 - 3.6e-06 27.0 0.1 1.4e-05 25.1 0.1 2.0 1 1 0 1 1 1 1 FAD-binding domain Myc_target_1 PF15179.6 OAG08160.1 - 0.0019 18.1 0.0 0.0044 16.9 0.0 1.6 2 0 0 2 2 2 1 Myc target protein 1 EphA2_TM PF14575.6 OAG08160.1 - 0.019 15.8 0.0 0.036 14.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OAG08160.1 - 0.045 13.2 3.0 0.071 12.5 3.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 OAG08160.1 - 0.19 11.7 2.4 0.35 10.8 2.4 1.3 1 0 0 1 1 1 0 Syndecan domain Collectrin PF16959.5 OAG08160.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Renal amino acid transporter Adeno_E3_CR2 PF02439.15 OAG08160.1 - 0.27 11.0 1.4 0.48 10.2 1.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ECH_1 PF00378.20 OAG08161.1 - 5.9e-74 248.5 0.0 7.5e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG08161.1 - 5.3e-35 121.5 0.2 3.2e-31 109.1 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PrpR_N PF06506.11 OAG08161.1 - 0.018 14.6 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Propionate catabolism activator Rer1 PF03248.13 OAG08162.1 - 2.1e-77 258.7 2.2 2.4e-77 258.5 2.2 1.0 1 0 0 1 1 1 1 Rer1 family AAA PF00004.29 OAG08163.1 - 2.1e-40 138.2 0.0 4.2e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAG08163.1 - 2.7e-19 68.9 0.3 5.7e-19 67.8 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAG08163.1 - 1.6e-07 31.0 0.0 3.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG08163.1 - 0.00014 22.3 1.5 0.02 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAG08163.1 - 0.00017 21.6 1.1 0.00053 20.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG08163.1 - 0.0003 20.6 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG08163.1 - 0.0015 18.8 1.8 0.082 13.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 OAG08163.1 - 0.0015 18.7 0.9 0.011 15.8 0.0 2.8 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) JIP_LZII PF16471.5 OAG08163.1 - 0.0038 17.3 3.0 0.012 15.7 3.0 1.8 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II PhoH PF02562.16 OAG08163.1 - 0.0046 16.4 0.2 0.08 12.4 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 OAG08163.1 - 0.0071 15.8 0.1 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 OAG08163.1 - 0.011 15.0 0.0 0.031 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 OAG08163.1 - 0.011 15.9 0.0 0.034 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain CLZ PF16526.5 OAG08163.1 - 0.012 16.0 3.7 0.076 13.4 3.7 2.5 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IstB_IS21 PF01695.17 OAG08163.1 - 0.076 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAG08163.1 - 0.13 11.8 0.0 0.37 10.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAG08163.1 - 0.31 10.7 0.0 0.31 10.7 0.0 2.1 3 1 0 3 3 1 0 AAA domain DUF3419 PF11899.8 OAG08164.1 - 1.3e-154 515.1 0.0 1.7e-154 514.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 OAG08164.1 - 1.7e-09 37.7 0.0 4.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG08164.1 - 8.7e-07 29.6 0.0 1e-05 26.1 0.0 2.8 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG08164.1 - 1.5e-05 25.6 0.0 7.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG08164.1 - 0.00013 22.5 0.0 0.0014 19.2 0.0 2.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG08164.1 - 0.0013 18.6 0.0 0.0046 16.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG08164.1 - 0.0076 15.6 0.0 0.052 12.9 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAG08164.1 - 0.021 14.6 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OAG08164.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.12 OAG08166.1 - 1.8e-07 31.7 0.0 3.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG08166.1 - 8.4e-07 29.6 0.0 1.9e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG08166.1 - 0.00025 21.8 0.0 0.00055 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG08166.1 - 0.00067 19.5 0.0 0.00088 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG08166.1 - 0.045 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAG08166.1 - 0.07 12.9 0.0 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain LON_substr_bdg PF02190.16 OAG08167.1 - 2.9e-31 109.0 0.0 5.2e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 OAG08167.1 - 6.5e-15 54.7 18.6 7e-11 41.8 10.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG08167.1 - 4.6e-14 52.2 18.3 1e-06 28.7 3.6 3.3 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG08167.1 - 9.5e-12 44.6 17.5 9.6e-06 25.4 9.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG08167.1 - 2.2e-11 43.5 18.9 3.7e-06 26.8 8.2 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAG08167.1 - 6.4e-11 42.2 23.7 2.9e-06 27.3 6.0 3.5 3 1 1 4 4 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAG08167.1 - 2.4e-10 40.1 18.1 2.2e-06 27.4 8.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG08167.1 - 1.4e-09 38.1 22.2 5.9e-07 29.7 9.6 2.5 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 OAG08167.1 - 3.4e-08 33.2 20.3 1.5e-05 24.7 8.6 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OAG08167.1 - 1.6e-05 25.0 18.6 8.5e-05 22.6 7.1 2.5 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OAG08167.1 - 0.00027 20.7 13.8 0.013 15.2 6.3 4.0 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OAG08167.1 - 0.0027 18.0 9.2 0.019 15.2 4.6 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain TerY_C PF15616.6 OAG08167.1 - 0.2 11.7 8.9 0.28 11.3 0.5 2.8 2 1 0 2 2 2 0 TerY-C metal binding domain Baculo_IE-1 PF05290.11 OAG08167.1 - 0.94 9.4 5.8 0.26 11.3 0.7 2.5 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Vps39_2 PF10367.9 OAG08167.1 - 6.8 7.2 8.0 7.1 7.1 0.8 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 RICTOR_N PF14664.6 OAG08168.1 - 6.7e-133 443.3 1.1 3.1e-131 437.8 0.2 3.4 3 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 OAG08168.1 - 1.5e-39 134.7 0.0 4.4e-35 120.4 0.0 4.0 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 OAG08168.1 - 1.4e-37 127.6 0.4 2.4e-35 120.4 0.1 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 OAG08168.1 - 3.9e-29 100.7 1.8 5.1e-28 97.1 0.3 3.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 OAG08168.1 - 1e-10 41.6 11.7 2.8e-10 40.2 11.7 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.6 OAG08168.1 - 0.046 14.1 0.8 33 5.0 0.0 4.4 4 0 0 4 4 4 0 HEAT repeats Uricase PF01014.18 OAG08169.1 - 1.4e-75 251.9 1.2 4.4e-41 140.2 0.6 2.0 2 0 0 2 2 2 2 Uricase Tom6 PF17112.5 OAG08170.1 - 0.00035 20.0 0.1 0.00041 19.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal Epimerase PF01370.21 OAG08171.1 - 5e-11 42.5 0.0 9.8e-11 41.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG08171.1 - 1.3e-08 34.7 0.0 3.2e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG08171.1 - 1.5e-08 34.0 0.0 2.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG08171.1 - 0.00034 20.6 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG08171.1 - 0.00074 19.1 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family RELT PF12606.8 OAG08171.1 - 0.025 13.6 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 adh_short PF00106.25 OAG08171.1 - 0.13 11.7 0.7 0.76 9.2 0.7 2.0 1 1 0 1 1 1 0 short chain dehydrogenase TFIIB PF00382.19 OAG08172.1 - 1.1e-28 99.0 5.5 1.3e-17 63.6 0.1 2.7 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OAG08172.1 - 2.9e-22 78.9 1.6 2.9e-22 78.9 1.6 3.6 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 OAG08172.1 - 0.021 14.6 0.1 0.88 9.3 0.0 2.4 1 1 1 2 2 2 0 Cyclin, N-terminal domain DNA_pol3_delta2 PF13177.6 OAG08172.1 - 0.07 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Imm5 PF14423.6 OAG08172.1 - 2.5 8.3 5.1 0.71 10.1 0.8 2.1 2 0 0 2 2 2 0 Immunity protein Imm5 TPR_1 PF00515.28 OAG08174.1 - 1.2e-15 56.6 3.9 1e-06 28.3 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG08174.1 - 4e-14 51.5 3.4 4.6e-05 23.2 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG08174.1 - 1.2e-09 38.4 0.0 1e-05 25.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG08174.1 - 1.5e-08 34.2 0.8 0.0012 18.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.24 OAG08174.1 - 6.1e-08 32.5 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.6 OAG08174.1 - 7.7e-07 29.3 0.3 1.6 9.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG08174.1 - 2.5e-06 27.1 0.8 0.00013 21.6 0.1 3.5 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 OAG08174.1 - 3.7e-06 26.6 2.7 0.00013 21.7 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG08174.1 - 0.0014 18.7 0.2 0.29 11.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG08174.1 - 0.0099 16.5 2.4 0.16 12.7 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG08174.1 - 0.013 16.3 0.2 0.78 10.7 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG08174.1 - 0.065 13.6 0.1 3.2 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG08174.1 - 1.1 9.2 3.9 5.3 7.1 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HMA PF00403.26 OAG08175.1 - 2.1e-13 50.5 0.0 3.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 OAG08175.1 - 4.5e-09 36.6 0.0 9e-09 35.6 0.0 1.4 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.18 OAG08176.1 - 9.1e-43 145.5 0.0 1.2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 GP38 PF05268.11 OAG08177.1 - 0.43 10.2 13.2 0.55 9.8 13.2 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Cyto_heme_lyase PF01265.17 OAG08178.1 - 5.1e-116 387.3 1.4 6e-116 387.1 1.4 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Yip1 PF04893.17 OAG08180.1 - 1.7e-07 31.1 14.5 3.5e-07 30.1 14.4 1.6 1 1 0 1 1 1 1 Yip1 domain F-box-like PF12937.7 OAG08181.1 - 0.038 13.9 0.2 0.19 11.6 0.2 2.3 1 0 0 1 1 1 0 F-box-like FlhC PF05280.11 OAG08181.1 - 0.53 10.0 4.7 1.1 9.0 4.7 1.5 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) UFD1 PF03152.14 OAG08182.1 - 3.3e-27 95.1 0.0 2e-14 53.5 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 OAG08182.1 - 3.4e-07 30.4 0.8 1.1e-06 28.8 0.1 2.2 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Paf1 PF03985.13 OAG08183.1 - 1.4e-61 208.9 0.0 2e-61 208.3 0.0 1.2 1 1 0 1 1 1 1 Paf1 FA_hydroxylase PF04116.13 OAG08184.1 - 1e-26 93.8 18.6 1e-26 93.8 18.6 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Actin PF00022.19 OAG08185.1 - 3e-25 88.7 0.0 1.5e-12 46.9 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 OAG08185.1 - 0.00044 19.2 0.0 0.014 14.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 OAG08185.1 - 0.00047 19.4 0.1 0.044 13.0 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family Amidase PF01425.21 OAG08186.1 - 1.8e-97 327.1 0.0 1.3e-96 324.3 0.0 2.0 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 OAG08187.1 - 1.3e-06 27.4 0.1 1.8e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG08187.1 - 0.00056 20.0 7.6 0.0012 19.0 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rtf2 PF04641.12 OAG08191.1 - 5.9e-61 206.1 5.7 1e-60 205.4 5.7 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 OAG08191.1 - 0.0031 17.3 0.0 0.02 14.7 0.0 2.2 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 OAG08191.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF2603 PF10788.9 OAG08191.1 - 0.09 12.8 0.3 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) Pkinase PF00069.25 OAG08192.1 - 3.2e-69 233.2 0.0 4.3e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08192.1 - 2.7e-32 112.1 0.0 3.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG08192.1 - 0.0002 20.8 0.0 0.0033 16.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OAG08192.1 - 0.0088 16.7 3.6 0.56 10.9 0.8 2.8 2 0 0 2 2 2 2 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OAG08192.1 - 0.029 13.1 0.0 0.058 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Polysacc_deac_1 PF01522.21 OAG08193.1 - 4.7e-28 97.6 0.1 9.2e-28 96.6 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG08193.1 - 2.8e-15 56.5 83.2 6.2e-06 26.6 22.8 4.1 3 1 0 3 3 3 3 Chitin recognition protein DUF2334 PF10096.9 OAG08193.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAG08193.1 - 0.05 12.8 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Varsurf_PPLC PF03490.13 OAG08194.1 - 0.019 14.9 0.1 0.047 13.6 0.1 1.6 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C CHB_HEX_C_1 PF13290.6 OAG08194.1 - 0.034 14.2 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain CyRPA PF18638.1 OAG08194.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Cysteine-Rich Protective Antigen 6 bladed domain WD40 PF00400.32 OAG08195.1 - 1.6e-06 28.7 7.8 0.17 12.8 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG08195.1 - 0.027 14.8 0.0 8.8 6.7 0.0 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 OAG08196.1 - 6.2e-30 103.3 1.0 7.7e-30 103.0 1.0 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Kelch_5 PF13854.6 OAG08197.1 - 6.1e-28 96.3 2.0 9.1e-05 22.4 0.0 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OAG08197.1 - 2.1e-26 91.2 2.6 2.1e-08 34.1 0.0 5.9 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OAG08197.1 - 1.4e-22 79.5 8.4 0.00015 22.0 0.1 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG08197.1 - 2.1e-21 75.7 16.2 5.4e-07 29.5 0.1 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 OAG08197.1 - 7e-19 67.1 7.5 1.6e-07 30.7 0.0 6.6 7 1 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 OAG08197.1 - 1.6e-14 53.2 5.9 0.0017 18.2 0.7 6.4 6 1 0 6 6 6 4 Kelch motif ABC1 PF03109.16 OAG08198.1 - 6.8e-21 74.6 0.0 3.5e-18 65.9 0.0 2.5 1 1 0 1 1 1 1 ABC1 family RIO1 PF01163.22 OAG08198.1 - 0.007 16.0 0.0 0.038 13.6 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Raf1_HTH PF18579.1 OAG08198.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain Pyr_redox_2 PF07992.14 OAG08199.1 - 7.3e-22 77.9 0.0 3.4e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG08199.1 - 2.2e-16 59.4 0.1 5.3e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG08199.1 - 4.3e-16 59.0 0.0 3.4e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG08199.1 - 1.3e-12 47.6 0.0 4.9e-11 42.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG08199.1 - 6.3e-12 45.5 0.0 2.6e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG08199.1 - 5.5e-06 26.9 0.0 0.00024 21.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG08199.1 - 7.6e-06 26.0 0.0 4 7.4 0.0 4.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG08199.1 - 2.5e-05 23.6 0.0 0.025 13.7 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 OAG08199.1 - 4.3e-05 22.7 0.0 0.054 12.5 0.0 2.6 2 1 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 OAG08199.1 - 5.6e-05 22.0 0.0 0.17 10.6 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 OAG08199.1 - 0.00014 21.6 0.6 1.4 8.4 0.1 3.7 3 1 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG08199.1 - 0.00029 20.2 0.0 0.00094 18.6 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG08199.1 - 0.00037 19.8 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OAG08199.1 - 0.00053 19.3 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 OAG08199.1 - 0.0006 20.2 0.0 0.0036 17.7 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 OAG08199.1 - 0.001 19.3 0.1 0.0028 17.8 0.0 1.7 2 0 0 2 2 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OAG08199.1 - 0.0011 19.0 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAG08199.1 - 0.0018 18.2 0.0 0.006 16.5 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAG08199.1 - 0.0056 15.8 0.0 0.58 9.2 0.0 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 OAG08199.1 - 0.0076 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 OAG08199.1 - 0.028 14.0 0.1 0.065 12.8 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OAG08199.1 - 0.034 14.7 0.3 0.1 13.2 0.0 1.9 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 OAG08199.1 - 0.038 13.3 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OAG08199.1 - 0.06 13.0 0.1 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 OAG08199.1 - 0.21 10.9 2.0 3.9 6.7 0.1 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase RVT_thumb PF06817.14 OAG08200.1 - 0.023 14.5 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RTP1_C2 PF10304.9 OAG08200.1 - 0.05 13.3 0.8 0.1 12.3 0.8 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 DUF5491 PF17595.2 OAG08200.1 - 0.098 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5491) RCC1 PF00415.18 OAG08201.1 - 9.5e-63 208.6 3.6 5.6e-11 42.9 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG08201.1 - 9e-36 121.0 24.2 1.3e-08 34.5 1.5 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Metallophos PF00149.28 OAG08202.1 - 1.7e-10 41.8 2.3 1.7e-10 41.8 2.3 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Caps_synth PF05704.12 OAG08203.1 - 3.8e-14 52.7 0.0 5.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 OAG08203.1 - 2.5e-06 28.0 0.0 4.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Abhydrolase_6 PF12697.7 OAG08204.1 - 9.6e-21 75.4 0.7 1.3e-20 75.0 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG08204.1 - 6.3e-16 58.8 0.1 9.7e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG08204.1 - 2e-12 46.9 0.1 6.9e-12 45.1 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OAG08204.1 - 0.0016 18.1 0.0 0.0079 15.8 0.0 1.9 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 OAG08204.1 - 0.0035 17.3 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OAG08204.1 - 0.0061 16.1 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OAG08204.1 - 0.029 14.2 0.0 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0228 PF05727.11 OAG08204.1 - 0.18 11.6 0.1 0.27 11.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) Zn_clus PF00172.18 OAG08205.1 - 3e-08 33.6 5.7 5.8e-08 32.7 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 OAG08205.1 - 0.024 14.1 0.4 0.049 13.1 0.0 1.7 2 0 0 2 2 2 0 Aflatoxin regulatory protein DUF2263 PF10021.9 OAG08206.1 - 1.1e-18 68.1 0.0 1.4e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 OAG08206.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Macro domain Nic96 PF04097.14 OAG08207.1 - 5.6e-192 639.5 0.2 6.9e-192 639.2 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Med27 PF11571.8 OAG08209.1 - 3.3e-13 49.8 0.2 8.3e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 Nup54_57_C PF18570.1 OAG08209.1 - 2.3 7.9 7.8 2.9 7.5 1.9 2.6 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain GPI-anchored PF10342.9 OAG08210.1 - 0.034 14.9 0.5 0.071 13.9 0.5 1.6 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_2 PF02368.18 OAG08210.1 - 0.36 10.8 6.5 5.8 6.9 6.5 2.6 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 2) RNase_T PF00929.24 OAG08212.1 - 8.7e-28 97.9 0.2 9.9e-28 97.7 0.2 1.0 1 0 0 1 1 1 1 Exonuclease DNA_pol_B PF00136.21 OAG08213.1 - 4e-116 388.5 0.5 5.7e-116 387.9 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 OAG08213.1 - 1.3e-61 207.5 0.3 3e-61 206.4 0.3 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OAG08213.1 - 1.9e-48 165.3 0.2 1.1e-47 162.9 0.0 2.2 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 OAG08213.1 - 1.5e-26 92.2 13.0 1.3e-25 89.3 8.7 2.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 OAG08213.1 - 0.0031 16.4 0.0 0.0083 15.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Fe-S_biosyn PF01521.20 OAG08214.1 - 5.5e-14 52.3 0.0 7e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.19 OAG08215.1 - 5.1e-14 52.0 0.0 8.1e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG08215.1 - 0.015 13.8 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3515 PF12028.8 OAG08216.1 - 0.0093 15.7 0.4 0.022 14.5 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3515) ABA_GPCR PF12430.8 OAG08218.1 - 1.8e-56 190.8 5.1 1.8e-56 190.8 5.1 2.4 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OAG08218.1 - 8.2e-25 86.7 0.7 9.5e-24 83.3 0.1 2.7 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF3169 PF11368.8 OAG08218.1 - 0.055 13.0 0.4 0.28 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Usp PF00582.26 OAG08219.1 - 4.8e-22 79.0 0.0 5.6e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF585 PF04522.12 OAG08219.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF585) RAC_head PF16717.5 OAG08220.1 - 1.1e-32 112.9 4.2 1.1e-32 112.9 4.2 3.2 4 0 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 OAG08220.1 - 4.5e-20 71.6 0.2 1.7e-19 69.7 0.2 2.1 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.19 OAG08220.1 - 0.74 7.7 9.0 1.2 6.9 9.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GRIP PF01465.20 OAG08221.1 - 1.7e-17 63.0 0.4 4.2e-17 61.8 0.4 1.7 1 0 0 1 1 1 1 GRIP domain Cep57_CLD_2 PF14197.6 OAG08221.1 - 0.0018 18.3 4.5 0.0018 18.3 4.5 13.1 5 4 7 12 12 12 2 Centrosome localisation domain of PPC89 APG6_N PF17675.1 OAG08221.1 - 0.0028 18.2 7.6 0.0028 18.2 7.6 10.5 2 2 7 9 9 9 3 Apg6 coiled-coil region GAS PF13851.6 OAG08221.1 - 0.068 12.5 147.5 0.028 13.7 14.9 9.2 3 2 6 9 9 9 0 Growth-arrest specific micro-tubule binding Trans_reg_C PF00486.28 OAG08221.1 - 0.85 9.7 6.4 30 4.8 0.3 4.4 4 0 0 4 4 4 0 Transcriptional regulatory protein, C terminal Spc7 PF08317.11 OAG08221.1 - 1.2 8.0 155.4 0.11 11.4 11.0 8.6 2 2 5 8 8 8 0 Spc7 kinetochore protein Leu_zip PF15294.6 OAG08221.1 - 2.2 7.7 126.5 0.64 9.5 19.0 7.7 3 2 3 7 7 7 0 Leucine zipper ATG16 PF08614.11 OAG08221.1 - 3.2 7.9 179.4 0.2 11.8 19.8 9.9 2 1 9 11 11 11 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 OAG08221.1 - 4.7 7.6 149.6 0.05 14.0 15.1 7.5 2 2 4 6 6 6 0 Fez1 Pkinase PF00069.25 OAG08222.1 - 2.8e-39 135.1 0.1 1.3e-22 80.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08222.1 - 8.6e-15 54.7 0.2 3.3e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG08222.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Bax1-I PF01027.20 OAG08223.1 - 0.072 12.9 0.0 0.082 12.7 0.0 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 bZIP_1 PF00170.21 OAG08224.1 - 2.5e-10 40.3 9.3 9.7e-10 38.4 9.3 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG08224.1 - 0.03 14.4 10.6 0.12 12.5 6.7 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Imm32 PF15566.6 OAG08224.1 - 0.15 11.8 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 32 MSA-2c PF12238.8 OAG08224.1 - 0.17 11.9 10.0 0.053 13.5 0.7 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF5327 PF17261.2 OAG08224.1 - 2.2 9.0 12.4 6.2 7.6 2.8 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5327) Pterin_4a PF01329.19 OAG08225.1 - 6.3e-24 84.0 0.0 9.3e-24 83.4 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase RNA_pol_3_Rpc31 PF11705.8 OAG08227.1 - 6.1e-47 160.8 10.5 7.3e-47 160.5 10.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RPN2_C PF18004.1 OAG08227.1 - 0.61 10.0 6.4 0.9 9.4 6.4 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 OAG08227.1 - 1.1 8.5 20.0 1.3 8.3 20.0 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 OAG08227.1 - 7.7 5.2 8.5 9.1 4.9 8.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SH3_11 PF18103.1 OAG08228.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain COesterase PF00135.28 OAG08229.1 - 2.6e-80 270.7 0.2 4.5e-70 237.0 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG08229.1 - 0.00036 20.5 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3433 PF11915.8 OAG08231.1 - 2.3e-44 149.8 8.3 3.4e-23 81.9 0.6 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Orai-1 PF07856.12 OAG08231.1 - 0.038 13.7 0.1 0.098 12.3 0.1 1.7 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF3169 PF11368.8 OAG08231.1 - 0.088 12.3 5.3 0.26 10.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF4064 PF13273.6 OAG08231.1 - 1.5 9.2 4.6 24 5.3 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4231 PF14015.6 OAG08231.1 - 2.6 8.5 6.0 0.76 10.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Arf PF00025.21 OAG08236.1 - 2e-74 248.8 0.0 2.3e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG08236.1 - 2.1e-14 53.8 0.0 2.8e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG08236.1 - 3.6e-12 46.1 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG08236.1 - 1.7e-11 43.9 0.4 1.8e-07 30.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAG08236.1 - 5.3e-11 42.4 0.0 6.3e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG08236.1 - 1.1e-08 34.7 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG08236.1 - 1.2e-06 28.5 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG08236.1 - 0.00028 20.5 0.0 0.023 14.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OAG08236.1 - 0.0022 17.0 0.1 0.0066 15.5 0.0 1.8 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 OAG08236.1 - 0.016 14.8 0.5 0.052 13.1 0.5 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 OAG08236.1 - 0.075 13.6 0.2 0.24 11.9 0.1 1.7 1 1 1 2 2 2 0 AAA domain Methyltransf_2 PF00891.18 OAG08239.1 - 1.7e-21 76.5 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAG08239.1 - 0.0037 17.2 0.1 0.0088 16.0 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain FAD_binding_4 PF01565.23 OAG08240.1 - 2.3e-19 69.5 0.2 5.4e-19 68.3 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG08240.1 - 1.1e-09 38.2 0.1 3e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like RCC1 PF00415.18 OAG08241.1 - 1.4e-19 70.4 0.3 0.0002 21.9 0.0 6.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG08241.1 - 1.8e-19 69.0 19.0 1.5e-06 27.8 0.3 5.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S9 PF00380.19 OAG08242.1 - 3.3e-33 114.8 0.2 3.7e-33 114.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ChAPs PF09295.10 OAG08243.1 - 2.7e-153 510.7 0.0 3.4e-153 510.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 OAG08243.1 - 4.2e-07 30.4 0.0 0.0038 17.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG08243.1 - 6.8e-06 26.5 1.1 2.5 9.2 0.0 4.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG08243.1 - 0.00019 21.3 5.7 0.14 12.3 0.8 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG08243.1 - 0.012 15.8 2.0 3.8 7.8 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAG08243.1 - 0.016 14.4 0.7 0.76 8.9 0.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG08243.1 - 0.022 15.4 0.2 73 4.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG08243.1 - 0.056 13.6 0.1 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG08243.1 - 0.067 13.4 0.1 3.4 8.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG08243.1 - 0.1 12.5 4.1 3.3 7.7 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG08243.1 - 0.21 11.9 3.0 40 4.6 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat HTH_5 PF01022.20 OAG08244.1 - 0.055 13.3 0.9 0.24 11.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family FMN_dh PF01070.18 OAG08245.1 - 3.4e-83 279.5 0.3 1.6e-49 168.8 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG08245.1 - 0.0033 16.5 0.1 0.013 14.5 0.1 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Peptidase_M19 PF01244.21 OAG08245.1 - 0.013 14.7 0.0 0.054 12.6 0.0 1.9 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) Glu_synthase PF01645.17 OAG08245.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase AAL_decarboxy PF03306.13 OAG08246.1 - 1.4e-27 96.4 0.0 1.1e-25 90.2 0.0 2.0 1 1 0 1 1 1 1 Alpha-acetolactate decarboxylase PGM_PMM_I PF02878.16 OAG08247.1 - 2.1e-29 102.0 0.0 3.3e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OAG08247.1 - 3.8e-25 88.3 0.0 6.8e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAG08247.1 - 3.1e-15 56.6 0.0 7.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OAG08247.1 - 9.7e-10 38.5 0.0 2.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SIN1_PH PF16979.5 OAG08247.1 - 0.14 12.5 0.0 14 6.0 0.0 2.9 3 0 0 3 3 3 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology XPG_I_2 PF12813.7 OAG08248.1 - 9.4e-40 136.6 0.7 1.2e-39 136.3 0.0 1.6 2 0 0 2 2 2 1 XPG domain containing XPG_I PF00867.18 OAG08248.1 - 0.0092 16.3 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OAG08248.1 - 0.022 15.2 1.9 0.034 14.6 0.0 2.2 2 0 0 2 2 2 0 XPG N-terminal domain Iron_permease PF04120.12 OAG08248.1 - 0.18 11.6 0.5 0.4 10.4 0.5 1.5 1 0 0 1 1 1 0 Low affinity iron permease DUF3309 PF11752.8 OAG08249.1 - 0.036 14.1 1.0 0.081 13.0 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) DAGK_cat PF00781.24 OAG08250.1 - 1.6e-07 30.9 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Dioxygenase_C PF00775.21 OAG08251.1 - 1.2e-42 145.4 0.0 1.7e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG08251.1 - 2.6e-30 104.1 0.0 4.5e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Isochorismatase PF00857.20 OAG08253.1 - 2.7e-28 99.3 0.0 5e-28 98.5 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family OPT PF03169.15 OAG08254.1 - 8.1e-197 655.6 31.9 9.5e-197 655.4 31.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BCS1_N PF08740.11 OAG08255.1 - 1.6e-39 135.8 0.3 2.4e-39 135.3 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAG08255.1 - 1.9e-17 63.9 0.0 3.7e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAG08255.1 - 1.1e-05 24.7 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 OAG08255.1 - 0.0002 21.8 0.1 0.0015 18.9 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OAG08255.1 - 0.0029 17.2 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAG08255.1 - 0.0041 16.6 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_21 PF13304.6 OAG08255.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 OAG08255.1 - 0.012 15.4 0.0 0.072 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OAG08255.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.17 OAG08255.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.6 OAG08255.1 - 0.016 15.8 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG08255.1 - 0.022 15.2 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 OAG08255.1 - 0.034 13.9 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OAG08255.1 - 0.041 14.4 0.0 0.093 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 OAG08255.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 OAG08255.1 - 0.054 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 OAG08255.1 - 0.074 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG08255.1 - 0.094 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAG08255.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OAG08255.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAG08255.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TOC159_MAD PF11886.8 OAG08256.1 - 0.023 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain EthD PF07110.11 OAG08257.1 - 5.8e-14 53.0 0.0 7.9e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG08257.1 - 3.9e-06 27.3 0.1 1.2e-05 25.8 0.1 2.0 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Big_1 PF02369.16 OAG08257.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) CN_hydrolase PF00795.22 OAG08258.1 - 7.5e-35 120.5 0.0 1e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_11 PF00457.17 OAG08259.1 - 2.3e-54 183.7 8.6 3.5e-54 183.1 8.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF2256 PF10013.9 OAG08261.1 - 2.4e-06 27.6 1.9 6.2e-06 26.2 1.9 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC5 PF06221.13 OAG08261.1 - 0.051 13.6 0.2 0.091 12.8 0.2 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-MYND PF01753.18 OAG08261.1 - 0.12 12.4 2.6 0.33 11.1 2.6 1.7 1 0 0 1 1 1 0 MYND finger UPF0016 PF01169.19 OAG08263.1 - 2.2e-41 140.0 24.3 5.3e-22 77.9 8.7 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Cyclin_N PF00134.23 OAG08264.1 - 4.8e-15 55.4 0.2 1.7e-14 53.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 OAG08264.1 - 0.00045 20.2 0.4 0.72 9.9 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 OAG08264.1 - 0.0016 18.5 0.8 0.032 14.3 0.0 2.6 2 1 0 2 2 2 1 Cyclin, C-terminal domain Trypan_PARP PF05887.11 OAG08264.1 - 0.011 15.6 1.3 0.011 15.6 1.3 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_3 PF07859.13 OAG08265.1 - 7.3e-40 137.1 0.5 1.4e-39 136.1 0.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Seipin PF06775.14 OAG08266.1 - 3e-54 184.1 0.0 4.3e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) zf-PARP PF00645.18 OAG08270.1 - 5.7e-21 75.2 0.2 1.7e-20 73.7 0.2 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CHZ PF09649.10 OAG08271.1 - 0.00029 20.2 2.3 0.00055 19.3 2.3 1.5 1 0 0 1 1 1 1 Histone chaperone domain CHZ Meth_synt_2 PF01717.18 OAG08273.1 - 5e-14 52.3 0.0 1.7e-08 34.2 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG08273.1 - 0.00057 19.5 0.0 0.026 14.1 0.0 2.4 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain CKS PF01111.19 OAG08273.1 - 0.022 15.0 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit Epimerase PF01370.21 OAG08274.1 - 1.7e-17 63.7 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG08274.1 - 2.2e-12 46.6 0.0 3.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG08274.1 - 1.3e-08 34.3 0.0 0.00068 18.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG08274.1 - 2.7e-08 33.6 0.3 1.3e-07 31.4 0.3 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG08274.1 - 2.1e-05 24.5 1.3 4e-05 23.6 0.3 2.0 2 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 OAG08274.1 - 0.0022 17.9 0.1 0.0081 16.1 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 OAG08274.1 - 0.0024 17.4 1.2 0.0059 16.1 0.1 2.1 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAG08274.1 - 0.0054 15.9 0.1 0.0084 15.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG08274.1 - 0.0083 15.7 1.0 0.047 13.2 0.2 2.2 2 1 0 2 2 2 1 NmrA-like family NTF2 PF02136.20 OAG08275.1 - 2e-31 109.1 0.1 2.2e-31 108.9 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 OAG08275.1 - 4.9e-05 23.7 0.0 5.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 OAG08275.1 - 0.016 15.9 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Thiolase_N PF00108.23 OAG08276.1 - 7.8e-73 245.0 1.7 1e-72 244.7 1.2 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG08276.1 - 3.9e-41 139.5 0.3 1.3e-40 137.9 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG08276.1 - 0.00085 19.0 0.6 0.0019 17.8 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF3245 PF11595.8 OAG08277.1 - 1.9e-05 25.2 1.4 1.9e-05 25.2 1.4 3.4 2 2 1 3 3 3 2 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.10 OAG08278.1 - 2.5e-76 255.8 1.7 2.5e-76 255.8 1.7 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 OAG08278.1 - 6.6e-26 91.0 0.3 6.6e-26 91.0 0.3 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 OAG08278.1 - 1.3e-10 41.1 0.4 3.3e-10 39.8 0.4 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OAG08278.1 - 0.003 17.4 1.8 0.066 13.0 0.3 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain VID27_N PF17748.1 OAG08278.1 - 0.045 13.6 0.6 0.081 12.8 0.6 1.3 1 0 0 1 1 1 0 VID27 N-terminal region TRI12 PF06609.13 OAG08279.1 - 7.2e-88 295.5 25.2 9.5e-88 295.1 25.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG08279.1 - 1.4e-24 86.7 52.4 2.1e-24 86.1 46.2 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG08279.1 - 5.7e-11 41.9 7.1 5.7e-11 41.9 7.1 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.12 OAG08279.1 - 0.0082 16.3 0.3 0.0082 16.3 0.3 2.5 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 Phytase-like PF13449.6 OAG08280.1 - 1.7e-38 133.2 0.1 2.3e-38 132.8 0.1 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase DUF3328 PF11807.8 OAG08282.1 - 2.7e-21 76.4 0.1 4.4e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FXR_C1 PF16096.5 OAG08282.1 - 0.086 13.1 2.4 0.16 12.2 2.4 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 p450 PF00067.22 OAG08283.1 - 3.6e-65 220.5 0.0 4.8e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Varsurf_PPLC PF03490.13 OAG08284.1 - 0.00036 20.4 1.2 0.0026 17.7 0.0 2.7 3 0 0 3 3 3 1 Variant-surface-glycoprotein phospholipase C HET PF06985.11 OAG08285.1 - 1.4e-25 90.4 0.1 8.4e-23 81.3 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DSPn PF14671.6 OAG08286.1 - 0.13 12.7 0.4 0.99 9.8 0.1 2.2 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half Brr6_like_C_C PF10104.9 OAG08287.1 - 1.7e-38 131.4 1.0 2.2e-38 131.0 1.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain U1snRNP70_N PF12220.8 OAG08288.1 - 8.5 7.1 14.0 18 6.1 6.6 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Aldose_epim PF01263.20 OAG08289.1 - 2.1e-49 168.5 1.1 2.6e-49 168.2 1.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase MS_channel PF00924.18 OAG08293.1 - 1.1e-18 67.5 0.7 2.1e-18 66.6 0.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAG08293.1 - 0.0015 17.9 0.2 0.0043 16.5 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OAG08293.1 - 0.005 16.3 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG08293.1 - 0.0099 15.7 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAG08293.1 - 0.012 16.1 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair LRR19-TM PF15176.6 OAG08293.1 - 0.5 10.4 1.8 0.8 9.7 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF4207 PF13904.6 OAG08294.1 - 0.00014 21.6 2.1 0.048 13.4 0.5 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4207) DUF4596 PF15363.6 OAG08294.1 - 0.0024 18.1 0.2 15 5.9 0.0 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF4596) SH3_4 PF06347.13 OAG08294.1 - 0.0039 17.0 2.5 15 5.5 0.1 3.3 2 1 0 3 3 3 3 Bacterial SH3 domain DUF3328 PF11807.8 OAG08295.1 - 5.7e-32 111.3 0.3 1.1e-31 110.3 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease PF00324.21 OAG08296.1 - 1.7e-112 376.5 32.7 2.1e-112 376.2 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG08296.1 - 2.8e-35 122.0 39.1 3.4e-35 121.7 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 OAG08298.1 - 7.6e-11 41.5 14.5 9e-11 41.3 14.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG08298.1 - 8.5e-05 21.6 1.7 8.5e-05 21.6 1.7 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter Pkinase PF00069.25 OAG08300.1 - 4.8e-53 180.2 0.0 6.2e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08300.1 - 5.2e-33 114.4 0.0 6.4e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG08300.1 - 0.00021 21.3 0.1 0.00055 19.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG08300.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG08300.1 - 0.18 10.7 0.0 0.18 10.7 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Fungal_trans PF04082.18 OAG08302.1 - 9.7e-16 57.6 0.0 1.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3343 PF11823.8 OAG08303.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) DUF2561 PF10812.8 OAG08304.1 - 0.063 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) FAM176 PF14851.6 OAG08304.1 - 6.2 6.5 7.0 16 5.2 6.9 1.7 1 1 0 1 1 1 0 FAM176 family Zn_clus PF00172.18 OAG08305.1 - 1.7e-07 31.2 9.6 3.2e-07 30.3 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG08305.1 - 2.9e-07 29.6 0.7 5.9e-07 28.6 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1768 PF08719.11 OAG08306.1 - 1.7e-53 181.2 0.3 2.1e-53 180.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) AAA_lid_6 PF17866.1 OAG08306.1 - 0.48 10.7 4.4 4.4 7.6 0.2 2.4 2 0 0 2 2 2 0 AAA lid domain Adaptin_N PF01602.20 OAG08307.1 - 4.1e-122 408.4 6.2 4.9e-122 408.2 6.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OAG08307.1 - 1.4e-47 160.6 0.0 3.4e-47 159.3 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OAG08307.1 - 4.8e-18 65.5 0.0 9.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAG08307.1 - 5.3e-06 26.6 1.9 0.017 15.1 0.0 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OAG08307.1 - 0.066 13.4 0.3 0.59 10.3 0.3 2.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 KAP PF05804.12 OAG08309.1 - 0.017 13.3 3.8 0.027 12.6 0.9 2.2 1 1 0 2 2 2 0 Kinesin-associated protein (KAP) DPM3 PF08285.11 OAG08310.1 - 4.1e-38 129.5 0.2 4.6e-38 129.3 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Oxidored-like PF09791.9 OAG08311.1 - 5.8e-25 86.7 4.9 5.8e-25 86.7 4.9 1.7 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal CENP-P PF13096.6 OAG08312.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Aldo_ket_red PF00248.21 OAG08314.1 - 1.1e-12 47.8 0.0 2.2e-12 46.8 0.0 1.5 1 1 1 2 2 2 1 Aldo/keto reductase family DJ-1_PfpI PF01965.24 OAG08315.1 - 4.6e-09 36.3 0.0 6.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Bac_rhamnosid6H PF17389.2 OAG08316.1 - 4.7e-11 42.5 0.7 5e-09 35.9 0.4 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 OAG08316.1 - 0.00022 20.2 0.6 0.00022 20.2 0.6 1.4 2 0 0 2 2 2 1 Trehalase Bac_rhamnosid_C PF17390.2 OAG08316.1 - 0.00034 20.3 0.0 0.00083 19.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Glyco_hydro_36 PF17167.4 OAG08316.1 - 0.056 12.1 0.3 0.12 11.0 0.3 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain adh_short PF00106.25 OAG08317.1 - 4.6e-19 68.6 0.1 1.2e-18 67.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG08317.1 - 7.2e-11 42.1 0.1 2.9e-10 40.1 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG08317.1 - 3e-09 37.0 0.3 5.7e-09 36.1 0.3 1.5 1 1 0 1 1 1 1 KR domain AMP-binding PF00501.28 OAG08318.1 - 1.2e-20 73.5 0.0 1.6e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 OAG08319.1 - 8.1e-12 44.7 29.4 8.1e-12 44.7 29.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG08319.1 - 1.2e-09 38.1 1.8 1.2e-09 38.1 1.8 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 OAG08319.1 - 2.5e-07 29.9 6.7 2.5e-07 29.9 6.7 3.6 4 0 0 4 4 4 1 Sugar (and other) transporter PUCC PF03209.15 OAG08319.1 - 0.17 10.9 9.4 0.042 12.9 5.7 1.9 2 0 0 2 2 2 0 PUCC protein ATPase_gene1 PF09527.10 OAG08319.1 - 0.55 10.4 11.7 2.6 8.3 0.4 3.4 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DAO PF01266.24 OAG08320.1 - 2.3e-40 139.3 0.0 2.6e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG08320.1 - 7.1e-06 25.5 0.0 0.063 12.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG08320.1 - 0.0041 17.1 0.2 3.6 7.6 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG08320.1 - 0.04 14.1 0.0 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Epimerase PF01370.21 OAG08320.1 - 0.076 12.5 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GIDA PF01134.22 OAG08320.1 - 0.098 11.7 0.0 0.41 9.7 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG08320.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase SNF2_N PF00176.23 OAG08321.1 - 1.3e-64 218.1 0.0 2.7e-64 217.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG08321.1 - 7.4e-19 68.1 0.0 3e-18 66.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG08321.1 - 9.9e-06 25.7 0.0 3.5e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG08321.1 - 0.025 13.8 0.0 0.066 12.4 0.0 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TFIIF_beta PF02270.15 OAG08321.1 - 0.14 12.3 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain DUF3275 PF11679.8 OAG08322.1 - 0.23 11.4 2.1 0.32 10.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) FIT1_2 PF17357.2 OAG08322.1 - 6.6 6.9 16.4 4.1 7.6 8.1 3.0 2 2 1 3 3 3 0 Facilitor Of iron transport 1 and 2 Bac_surface_Ag PF01103.23 OAG08324.1 - 2.2e-47 162.1 0.4 2.9e-47 161.8 0.4 1.1 1 0 0 1 1 1 1 Surface antigen PLU-1 PF08429.11 OAG08324.1 - 0.13 11.4 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 PLU-1-like protein UQ_con PF00179.26 OAG08325.1 - 4.3e-19 68.6 0.0 6.7e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sugar_tr PF00083.24 OAG08326.1 - 4.4e-108 362.0 18.4 5.1e-108 361.8 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG08326.1 - 9.4e-21 74.1 23.4 9.4e-21 74.1 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3147 PF11345.8 OAG08326.1 - 0.027 14.8 5.4 3.6 8.0 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) PAP_assoc PF03828.19 OAG08327.1 - 1.2e-19 70.3 0.0 3e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG08327.1 - 4.3e-06 26.9 0.0 1.8e-05 24.9 0.0 1.9 2 1 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAG08327.1 - 0.00032 20.7 0.0 0.00063 19.8 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_central PF04928.17 OAG08327.1 - 0.028 13.4 0.1 0.16 10.9 0.1 2.1 2 0 0 2 2 2 0 Poly(A) polymerase central domain FXMRP1_C_core PF12235.8 OAG08327.1 - 1.5 9.5 11.4 2.9 8.5 4.7 2.6 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal DUF3801 PF12687.7 OAG08328.1 - 0.0054 16.8 19.4 0.0054 16.8 19.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3801) NmrA PF05368.13 OAG08329.1 - 4.4e-15 55.9 0.0 6.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG08329.1 - 2.8e-12 46.9 0.0 4.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG08329.1 - 5.9e-08 32.5 0.2 2.5e-06 27.1 0.2 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG08329.1 - 6.7e-05 22.4 0.7 0.01 15.2 0.1 2.9 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG08329.1 - 0.00035 19.8 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_2 PF03446.15 OAG08329.1 - 0.054 13.7 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HlyIII PF03006.20 OAG08330.1 - 1e-64 218.3 14.6 1.2e-64 218.1 14.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 OAG08330.1 - 0.0038 17.3 0.1 0.018 15.1 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF2157 PF09925.9 OAG08330.1 - 0.014 15.1 6.5 0.22 11.3 0.6 3.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Saf_2TM PF18303.1 OAG08330.1 - 0.16 11.5 0.5 0.51 9.9 0.0 2.0 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain DUF4134 PF13572.6 OAG08330.1 - 0.56 10.5 4.7 1.9 8.8 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4134) DUF373 PF04123.13 OAG08330.1 - 1.2 8.5 6.4 8.7 5.7 6.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF373) HemS PF05171.12 OAG08331.1 - 0.045 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain Par3_HAL_N_term PF12053.8 OAG08331.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Brix PF04427.18 OAG08332.1 - 1.5e-49 168.8 0.1 1.9e-49 168.4 0.1 1.1 1 0 0 1 1 1 1 Brix domain Nucleo_P87 PF07267.11 OAG08332.1 - 2.5 6.9 7.9 23 3.7 6.6 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PBP_sp32 PF07222.12 OAG08332.1 - 3 7.2 7.9 89 2.4 9.3 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 MscS_TM PF12794.7 OAG08332.1 - 4.4 6.1 4.0 8.8 5.1 4.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 PPP4R2 PF09184.11 OAG08332.1 - 5.1 6.6 17.6 8.3 5.9 17.6 1.3 1 0 0 1 1 1 0 PPP4R2 DEAD PF00270.29 OAG08333.1 - 6.7e-48 162.8 0.0 1.1e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG08333.1 - 4.1e-31 107.6 0.0 1.8e-30 105.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG08333.1 - 0.00028 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG08333.1 - 0.00039 19.7 0.0 0.00068 18.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AC_N PF16214.5 OAG08333.1 - 0.21 10.7 0.9 0.33 10.0 0.9 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region MSA_2 PF00985.17 OAG08333.1 - 1.4 9.2 6.1 2.5 8.4 6.1 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Pox_Ag35 PF03286.14 OAG08333.1 - 6.6 6.5 7.6 8.1 6.2 5.6 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PHD PF00628.29 OAG08334.1 - 5.6e-11 42.2 7.9 8.7e-11 41.6 7.9 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 OAG08334.1 - 0.0049 16.8 5.7 0.0095 15.9 5.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 OAG08334.1 - 0.006 16.1 6.5 0.016 14.7 6.5 1.8 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.22 OAG08334.1 - 0.0069 16.2 1.8 0.013 15.3 1.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 OAG08334.1 - 0.0075 15.9 3.0 0.012 15.3 3.0 1.3 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-RRPl_C4 PF17026.5 OAG08334.1 - 0.0075 16.4 2.7 0.011 15.8 2.7 1.2 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type FYVE_2 PF02318.16 OAG08334.1 - 0.029 14.6 2.0 0.046 13.9 2.0 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger PSCyt3 PF07627.11 OAG08334.1 - 0.046 14.0 2.6 0.15 12.4 0.2 2.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1588) CoA_transf_3 PF02515.17 OAG08335.1 - 3.2e-124 414.8 0.0 3.7e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.17 OAG08336.1 - 1.5e-38 130.7 6.6 1.5e-19 69.8 0.0 3.2 3 0 0 3 3 3 3 Lumazine binding domain ApoL PF05461.11 OAG08337.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein L PrmA PF06325.13 OAG08338.1 - 2.2e-10 40.4 0.0 3.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAG08338.1 - 2.6e-10 40.9 0.0 6.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG08338.1 - 3.1e-09 36.8 0.1 4.9e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG08338.1 - 7.9e-07 29.6 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG08338.1 - 8.2e-06 25.0 0.1 1.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 OAG08338.1 - 2.5e-05 24.2 0.1 4.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG08338.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAG08338.1 - 0.00027 20.8 0.0 0.00042 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG08338.1 - 0.0032 18.2 0.0 0.0063 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG08338.1 - 0.0064 16.1 0.1 0.0098 15.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG08338.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 OAG08338.1 - 0.029 15.4 0.0 0.053 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OAG08338.1 - 0.095 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Kinesin PF00225.23 OAG08339.1 - 3.5e-62 210.3 0.0 5.1e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG08339.1 - 2.6e-10 40.4 0.2 1e-07 32.0 0.0 3.0 3 0 0 3 3 3 1 Microtubule binding bZIP_2 PF07716.15 OAG08339.1 - 0.0047 17.0 1.0 0.0047 17.0 1.0 2.3 3 0 0 3 3 3 1 Basic region leucine zipper TSC22 PF01166.18 OAG08339.1 - 0.027 14.8 1.0 0.072 13.4 1.0 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 OAG08339.1 - 0.076 13.1 0.9 0.24 11.5 0.5 2.0 2 0 0 2 2 1 0 bZIP transcription factor TolA_bind_tri PF16331.5 OAG08339.1 - 0.093 12.8 3.0 6.7 6.9 0.4 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 OAG08339.1 - 2.5 8.2 13.0 7 6.7 1.4 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OAG08339.1 - 3.2 7.0 13.0 11 5.3 13.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 OAG08339.1 - 5.2 7.1 12.1 0.48 10.5 2.2 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 OAG08339.1 - 6.2 7.0 15.6 69 3.6 1.6 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF87 PF01935.17 OAG08339.1 - 7.6 6.5 6.8 2.1 8.4 0.9 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain FAD_binding_3 PF01494.19 OAG08340.1 - 1.1e-18 67.7 0.0 2.6e-08 33.5 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG08340.1 - 1.8e-05 24.9 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG08340.1 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG08340.1 - 0.024 13.9 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG08340.1 - 0.032 14.8 0.0 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG08340.1 - 0.05 12.8 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.16 OAG08341.1 - 6.4e-37 127.3 29.8 6.4e-37 127.3 29.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG08341.1 - 4.8e-06 25.7 11.4 4.8e-06 25.7 11.4 2.1 1 1 1 2 2 2 1 MFS_1 like family ESSS PF10183.9 OAG08341.1 - 0.019 15.2 0.5 0.35 11.1 0.0 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Epiglycanin_C PF14654.6 OAG08341.1 - 9.2 6.4 6.3 0.87 9.7 0.2 2.4 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region YoqO PF14037.6 OAG08342.1 - 0.039 14.5 0.0 0.067 13.7 0.0 1.3 1 0 0 1 1 1 0 YoqO-like protein DNA_pol_phi PF04931.13 OAG08344.1 - 0.018 13.2 13.1 0.024 12.7 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi PARP PF00644.20 OAG08344.1 - 0.18 11.3 0.1 0.32 10.5 0.1 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain DUF3292 PF11696.8 OAG08345.1 - 0 1014.4 0.0 0 1014.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) MAPEG PF01124.18 OAG08346.1 - 4e-12 46.2 3.4 6.6e-12 45.5 3.4 1.3 1 0 0 1 1 1 1 MAPEG family Intg_mem_TP0381 PF09529.10 OAG08347.1 - 0.023 14.2 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) ESSS PF10183.9 OAG08347.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pex14_N PF04695.13 OAG08349.1 - 3e-42 144.9 1.0 3e-42 144.9 1.0 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 OAG08349.1 - 0.037 14.1 0.8 7.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B562 PF07361.11 OAG08349.1 - 0.047 14.3 0.5 0.11 13.2 0.5 1.6 1 0 0 1 1 1 0 Cytochrome b562 CYSTM PF12734.7 OAG08349.1 - 0.065 13.6 2.2 0.3 11.4 2.2 2.2 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF3584 PF12128.8 OAG08349.1 - 0.085 10.4 4.5 0.12 9.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EamA PF00892.20 OAG08349.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 EamA-like transporter family DUF1043 PF06295.12 OAG08349.1 - 0.75 9.8 3.5 0.37 10.8 0.9 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DASH_Spc19 PF08287.11 OAG08349.1 - 3.8 7.4 9.5 0.4 10.6 5.0 1.6 2 0 0 2 2 2 0 Spc19 zf-C4H2 PF10146.9 OAG08349.1 - 7.5 6.8 11.9 0.47 10.7 1.0 2.5 2 1 0 2 2 2 0 Zinc finger-containing protein MFS_1 PF07690.16 OAG08350.1 - 2.4e-11 43.2 43.4 1.4e-07 30.8 23.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TPR_10 PF13374.6 OAG08352.1 - 2.4e-09 36.8 0.0 3.4e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG08352.1 - 1.5e-05 25.2 0.2 0.00084 19.6 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG08353.1 - 8.9e-10 38.2 0.1 5.1e-09 35.7 0.1 2.1 2 1 0 2 2 2 1 NB-ARC domain HET PF06985.11 OAG08353.1 - 3.1e-07 30.9 13.7 3.7e-07 30.6 1.1 3.2 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) SecIII_SopE_N PF05364.14 OAG08353.1 - 0.029 14.4 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus TFIIA PF03153.13 OAG08353.1 - 0.079 12.9 7.5 0.13 12.2 7.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 OAG08353.1 - 0.11 12.9 5.3 3.5 8.0 5.3 3.1 1 1 0 1 1 1 0 AAA ATPase domain Oxysterol_BP PF01237.18 OAG08355.1 - 4.5e-67 226.5 11.3 5.7e-65 219.6 11.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DnaT PF17948.1 OAG08355.1 - 0.029 14.0 1.5 16 5.3 0.0 3.4 3 0 0 3 3 3 0 DnaT DNA-binding domain Fungal_trans PF04082.18 OAG08356.1 - 1.7e-07 30.5 0.0 2.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG08357.1 - 9.9e-41 139.8 71.6 1e-32 113.5 47.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG08357.1 - 0.00058 18.8 30.6 0.019 13.8 13.1 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Hva1_TUDOR PF11160.8 OAG08358.1 - 1.5e-15 57.1 2.5 1.5e-15 57.1 2.5 4.0 4 1 0 4 4 4 1 Hypervirulence associated proteins TUDOR domain adh_short PF00106.25 OAG08359.1 - 5.2e-14 52.2 0.0 3.1e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG08359.1 - 1.9e-08 34.2 0.0 0.0021 17.7 0.0 2.9 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Pec_lyase_C PF00544.19 OAG08360.1 - 5.4e-43 147.0 4.0 8.4e-43 146.4 4.0 1.3 1 0 0 1 1 1 1 Pectate lyase Tyrosinase PF00264.20 OAG08361.1 - 3.7e-45 154.9 2.7 4.6e-45 154.6 2.7 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Jiraiya PF15038.6 OAG08362.1 - 0.071 12.5 0.6 1.6 8.2 0.8 2.0 1 1 1 2 2 2 0 Jiraiya p450 PF00067.22 OAG08363.1 - 9.7e-58 196.0 0.0 1.4e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG08364.1 - 5e-17 61.8 0.0 6.1e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG08365.1 - 1.9e-52 178.6 0.0 2.6e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AP_endonuc_2 PF01261.24 OAG08366.1 - 1.6e-33 116.0 0.0 2.9e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GFO_IDH_MocA PF01408.22 OAG08367.1 - 5.2e-27 95.0 0.0 7.6e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG08367.1 - 6.4e-16 58.4 0.0 1.7e-15 57.0 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAG08367.1 - 0.0014 19.3 0.0 0.002 18.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4774 PF15999.5 OAG08367.1 - 0.014 15.2 1.6 0.074 12.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4774) Semialdhyde_dh PF01118.24 OAG08367.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.18 OAG08368.1 - 4.5e-15 55.4 0.1 1.5e-14 53.7 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG08368.1 - 1.1e-06 28.6 11.7 2.1e-06 27.7 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 OAG08369.1 - 3.4e-23 83.1 0.0 6.5e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 OAG08369.1 - 8.9e-19 67.5 0.0 1.8e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 OAG08369.1 - 1e-10 42.0 0.0 2.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 OAG08369.1 - 7.1e-10 38.5 0.1 1.4e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAG08369.1 - 1.3e-06 28.5 0.1 3.1e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG08369.1 - 0.021 15.4 0.2 0.054 14.1 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OAG08369.1 - 0.033 14.4 0.0 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AAA_16 PF13191.6 OAG08369.1 - 0.052 13.9 0.2 0.33 11.3 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain OCD_Mu_crystall PF02423.15 OAG08369.1 - 0.054 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Fasciclin PF02469.22 OAG08371.1 - 2.2e-47 160.4 9.4 2.6e-26 92.3 1.1 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF3377 PF11857.8 OAG08371.1 - 0.0071 16.2 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) CSTF2_hinge PF14327.6 OAG08371.1 - 0.014 15.8 3.2 2.1 8.8 0.3 3.5 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 Cyclin_N PF00134.23 OAG08374.1 - 0.0031 17.3 0.0 1.9 8.2 0.0 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG08374.1 - 0.13 12.3 1.6 0.16 12.1 0.2 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain PIG-Y PF15159.6 OAG08376.1 - 7e-24 84.5 7.0 1.1e-23 84.0 7.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 OAG08376.1 - 0.054 14.0 1.8 10 6.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2956 PF11169.8 OAG08376.1 - 5 7.4 4.8 5.3 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Cation_efflux PF01545.21 OAG08377.1 - 1.4e-09 38.0 7.3 1.8e-09 37.6 7.3 1.1 1 0 0 1 1 1 1 Cation efflux family SH PF01445.17 OAG08377.1 - 0.1 12.6 1.7 0.25 11.3 1.7 1.7 1 0 0 1 1 1 0 Viral small hydrophobic protein IBR PF01485.21 OAG08378.1 - 9.7e-14 51.4 35.0 4.7e-08 33.1 6.1 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain DUF2158 PF09926.9 OAG08378.1 - 0.00031 20.4 0.1 0.0009 18.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized small protein (DUF2158) Neur_chan_memb PF02932.16 OAG08379.1 - 0.17 11.9 1.0 0.2 11.7 1.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 OAG08379.1 - 1.1 8.0 5.7 1.2 7.9 5.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ish1 PF10281.9 OAG08380.1 - 4.8e-55 183.6 17.8 3.6e-14 52.8 0.0 5.4 5 0 0 5 5 5 5 Putative stress-responsive nuclear envelope protein SAP PF02037.27 OAG08380.1 - 0.0009 18.9 0.0 0.63 9.9 0.0 3.4 3 0 0 3 3 3 1 SAP domain Slx4 PF09494.10 OAG08380.1 - 0.03 14.3 2.3 5.4 7.0 0.0 4.0 4 1 0 4 4 4 0 Slx4 endonuclease HeH PF12949.7 OAG08380.1 - 0.031 14.0 0.1 4.7 7.0 0.0 3.3 3 0 0 3 3 3 0 HeH/LEM domain Apolipoprotein PF01442.18 OAG08380.1 - 0.2 11.5 8.5 0.084 12.7 0.5 3.0 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DHquinase_II PF01220.19 OAG08381.1 - 3e-62 208.3 0.0 3.4e-62 208.2 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Pyr_redox_2 PF07992.14 OAG08381.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Inositol_P PF00459.25 OAG08382.1 - 4.6e-81 272.3 0.0 5.2e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.11 OAG08383.1 - 6.4e-22 77.6 0.0 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 OAG08383.1 - 2.2e-06 27.3 0.3 5.9e-06 26.0 0.3 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAG08383.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG08383.1 - 0.049 14.1 0.1 0.08 13.4 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Sugar_tr PF00083.24 OAG08384.1 - 1.4e-138 462.6 21.6 1.6e-138 462.4 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG08384.1 - 1.1e-20 73.9 26.2 1.1e-20 73.9 26.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG08385.1 - 2.3e-80 270.7 29.4 2.8e-80 270.4 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG08385.1 - 1.4e-27 96.6 35.8 2.6e-27 95.7 35.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG08385.1 - 5.1e-07 28.5 3.2 8.9e-07 27.7 3.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trypsin_2 PF13365.6 OAG08386.1 - 0.00013 22.8 0.6 0.23 12.4 0.0 2.6 1 1 1 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 OAG08386.1 - 0.00033 20.5 2.7 0.1 12.4 0.1 2.4 1 1 1 2 2 2 2 Trypsin Peptidase_S46 PF10459.9 OAG08386.1 - 0.0011 17.7 0.1 0.0011 17.7 0.1 1.5 2 0 0 2 2 2 1 Peptidase S46 T4_tail_cap PF11091.8 OAG08386.1 - 0.033 13.1 0.8 0.14 11.1 1.1 1.7 2 0 0 2 2 2 0 Tail-tube assembly protein Peptidase_C3 PF00548.20 OAG08386.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Peptidase_S32 PF05579.13 OAG08386.1 - 0.084 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Aldo_ket_red PF00248.21 OAG08389.1 - 6.3e-67 225.8 0.0 8e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.14 OAG08389.1 - 0.0003 20.9 0.1 0.1 12.8 0.1 2.6 2 0 0 2 2 2 2 NAF domain LRR_8 PF13855.6 OAG08390.1 - 7.7e-37 124.9 47.1 5.5e-08 32.4 0.4 8.9 5 3 1 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OAG08390.1 - 5.6e-34 115.6 56.6 3.5e-06 27.3 3.8 10.7 6 4 6 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAG08390.1 - 1.6e-08 34.0 27.0 17 6.4 0.2 13.2 13 0 0 13 13 13 1 Leucine Rich Repeat LRR_6 PF13516.6 OAG08390.1 - 4.1e-08 32.6 34.4 4.3 7.6 0.1 11.8 13 0 0 13 13 13 6 Leucine Rich repeat LRR_9 PF14580.6 OAG08390.1 - 4.2e-07 29.6 18.2 0.37 10.3 0.6 5.9 2 2 4 6 6 6 6 Leucine-rich repeat Ribosomal_L13e PF01294.18 OAG08392.1 - 1.9e-75 252.7 5.0 1.9e-75 252.7 5.0 1.3 2 0 0 2 2 2 1 Ribosomal protein L13e HRI1 PF16815.5 OAG08393.1 - 1.6e-61 208.0 0.0 1.9e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Protein HRI1 SAP PF02037.27 OAG08394.1 - 0.0011 18.7 4.3 0.81 9.5 0.1 3.6 3 0 0 3 3 3 3 SAP domain CPSase_L_D3 PF02787.19 OAG08394.1 - 0.061 13.7 0.2 0.061 13.7 0.2 2.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain LPMO_10 PF03067.15 OAG08394.1 - 0.33 11.6 1.7 0.5 11.0 1.1 1.6 2 0 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Hid1 PF12722.7 OAG08394.1 - 2.6 6.1 5.0 3.6 5.6 5.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 OAG08394.1 - 3.4 7.7 9.4 3.1 7.9 4.6 2.2 2 0 0 2 2 2 0 DDHD domain Phage_Gp15 PF06854.11 OAG08395.1 - 0.012 15.6 0.6 1.1 9.2 0.9 2.5 2 0 0 2 2 2 0 Bacteriophage Gp15 protein CPSF100_C PF13299.6 OAG08395.1 - 1.6 8.9 7.4 6.3 6.9 4.7 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SCIMP PF15050.6 OAG08395.1 - 3.1 8.3 4.4 18 5.8 0.0 3.5 3 1 1 4 4 4 0 SCIMP protein Fumble PF03630.14 OAG08397.1 - 1.3e-139 465.0 0.0 1.6e-139 464.7 0.0 1.1 1 0 0 1 1 1 1 Fumble FAD_binding_4 PF01565.23 OAG08398.1 - 3.5e-22 78.7 6.2 5.5e-22 78.0 6.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG08398.1 - 2e-10 40.6 0.0 2e-10 40.6 0.0 2.1 3 0 0 3 3 3 1 Berberine and berberine like PSDC PF12588.8 OAG08399.1 - 1.6e-31 109.1 0.1 2.7e-31 108.4 0.1 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 OAG08399.1 - 1.3e-29 103.2 0.0 1.8e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MRJP PF03022.16 OAG08400.1 - 5.7e-27 94.8 0.2 2.5e-25 89.4 0.2 2.2 1 1 0 1 1 1 1 Major royal jelly protein Med17 PF10156.9 OAG08401.1 - 2.7e-79 267.1 0.0 3.9e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex GntR PF00392.21 OAG08401.1 - 0.074 12.7 0.1 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family ISN1 PF06437.11 OAG08402.1 - 7.2e-193 641.1 0.0 8.1e-193 640.9 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF536 PF04394.14 OAG08403.1 - 0.074 12.9 0.6 0.14 12.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF536 PBC PF03792.13 OAG08404.1 - 0.027 14.2 0.2 0.032 14.0 0.2 1.1 1 0 0 1 1 1 0 PBC domain NIR_SIR PF01077.22 OAG08404.1 - 0.037 13.5 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain SlyX PF04102.12 OAG08404.1 - 0.41 11.3 3.9 0.67 10.6 2.1 1.9 1 1 1 2 2 2 0 SlyX ADH_zinc_N PF00107.26 OAG08405.1 - 2.6e-13 50.1 0.0 5.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG08405.1 - 0.091 12.7 0.0 2.7 7.9 0.0 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-like domain GFO_IDH_MocA PF01408.22 OAG08406.1 - 2.8e-19 70.1 0.1 5.4e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG08406.1 - 6.5e-08 32.6 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain AAA_33 PF13671.6 OAG08406.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain NAD_binding_3 PF03447.16 OAG08406.1 - 0.018 15.7 0.1 0.035 14.7 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Biotin_carb_N PF00289.22 OAG08406.1 - 0.16 12.6 1.5 0.38 11.3 0.2 2.1 2 0 0 2 2 2 0 Biotin carboxylase, N-terminal domain FAR1 PF03101.15 OAG08407.1 - 3.8e-07 30.7 0.7 7.6e-07 29.7 0.7 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Laminin_II PF06009.12 OAG08407.1 - 0.29 11.2 2.1 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II DAO PF01266.24 OAG08408.1 - 7.1e-40 137.7 0.0 8.8e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG08408.1 - 2e-05 24.7 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG08408.1 - 7.2e-05 22.8 0.0 0.0044 17.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG08408.1 - 0.00012 21.4 0.0 0.0033 16.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG08408.1 - 0.0024 17.0 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 OAG08408.1 - 0.028 14.7 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 OAG08408.1 - 0.043 12.7 0.0 4.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 OAG08408.1 - 0.23 10.7 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Methyltransf_23 PF13489.6 OAG08409.1 - 1.3e-25 90.1 0.0 1.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG08409.1 - 1.4e-08 35.4 0.0 2.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG08409.1 - 6.5e-07 30.0 0.0 1.1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG08409.1 - 5.4e-06 27.0 0.0 9.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG08409.1 - 0.00014 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAG08409.1 - 0.0003 20.6 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF2235 PF09994.9 OAG08413.1 - 2.4e-78 263.4 0.0 3.1e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HET PF06985.11 OAG08414.1 - 1.1e-16 61.5 1.0 1.3e-16 61.2 1.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 OAG08415.1 - 0.0063 15.3 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Not1 PF04054.15 OAG08418.1 - 4.6e-130 433.8 0.0 1.2e-129 432.5 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OAG08418.1 - 1.6e-90 302.4 0.2 3.9e-90 301.2 0.2 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 OAG08418.1 - 2.2e-46 157.4 4.9 4.7e-46 156.4 4.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 OAG08418.1 - 1.8e-44 151.2 0.0 5.1e-44 149.7 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OAG08418.1 - 1e-31 110.0 0.2 2.4e-31 108.8 0.2 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FCH PF00611.23 OAG08421.1 - 8.7e-15 54.8 0.0 2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 OAG08421.1 - 2.6e-13 49.6 0.1 4.7e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG08421.1 - 8.8e-13 47.6 0.0 1.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG08421.1 - 7.6e-12 44.7 0.1 4.5e-11 42.3 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Rapsyn_N PF10579.9 OAG08421.1 - 0.11 12.6 0.1 0.34 11.1 0.1 1.9 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region PP_kinase_N PF13089.6 OAG08421.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.6 4 0 0 4 4 4 0 Polyphosphate kinase N-terminal domain ABC_tran PF00005.27 OAG08422.1 - 5.6e-30 104.6 0.0 1.4e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAG08422.1 - 5.2e-11 42.7 9.5 1.1e-10 41.6 9.5 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OAG08422.1 - 3e-06 26.9 0.0 1.3e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 OAG08422.1 - 0.014 15.2 1.6 0.046 13.5 0.3 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.22 OAG08422.1 - 0.024 14.3 0.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 OAG08422.1 - 0.034 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OAG08422.1 - 0.039 13.7 0.1 0.087 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG08422.1 - 0.087 13.1 0.1 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG08422.1 - 0.12 12.9 0.4 0.24 11.9 0.4 1.5 1 1 0 1 1 1 0 AAA domain Nanovirus_C8 PF05629.11 OAG08422.1 - 0.12 12.5 0.2 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 Nanovirus component 8 (C8) protein AAA_7 PF12775.7 OAG08422.1 - 0.13 11.8 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 OAG08422.1 - 0.28 11.2 1.0 5.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain OTT_1508_deam PF14441.6 OAG08424.1 - 6.1e-15 55.0 1.9 1.4e-14 53.9 1.9 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Phage_Mu_Gam PF07352.12 OAG08424.1 - 0.047 13.6 0.3 0.09 12.7 0.3 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein SesA PF17107.5 OAG08426.1 - 1e-24 87.1 0.5 2.5e-24 85.8 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_10 PF13374.6 OAG08426.1 - 8.1e-14 51.0 1.2 1.2e-10 40.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG08426.1 - 1.5e-13 50.8 0.3 1.7e-09 37.8 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG08426.1 - 6.3e-06 25.6 0.0 0.00029 20.1 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 OAG08426.1 - 0.021 15.2 5.0 0.16 12.4 0.7 3.8 2 2 0 2 2 2 0 AAA ATPase domain TPR_1 PF00515.28 OAG08426.1 - 0.022 14.6 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Helo_like_N PF17111.5 OAG08426.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins GalKase_gal_bdg PF10509.9 OAG08427.1 - 2.5e-21 74.9 0.1 4.9e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OAG08427.1 - 4.3e-15 55.7 0.7 9.9e-15 54.5 0.7 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG08427.1 - 1.1e-14 54.6 0.0 2.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_23 PF13384.6 OAG08427.1 - 0.19 11.6 0.0 0.5 10.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DUF3328 PF11807.8 OAG08428.1 - 2.3e-31 109.3 0.1 3.6e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1289 PF06945.13 OAG08429.1 - 2.6e-06 27.1 3.2 0.57 10.0 0.1 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF1289) Fer2_BFD PF04324.15 OAG08429.1 - 0.06 13.7 7.2 1 9.8 4.1 3.0 1 1 2 3 3 3 0 BFD-like [2Fe-2S] binding domain zf-C4pol PF14260.6 OAG08429.1 - 0.15 12.5 2.3 0.89 10.1 2.4 2.2 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 OAG08429.1 - 0.51 10.4 6.1 1.4 9.0 0.6 2.7 2 1 1 3 3 3 0 Double zinc ribbon DASH_Duo1 PF08651.10 OAG08430.1 - 1.4e-32 111.2 3.0 2.1e-32 110.7 3.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.13 OAG08430.1 - 0.0016 18.2 0.9 0.0016 18.2 0.9 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF745) DUF5082 PF16888.5 OAG08430.1 - 0.44 10.8 8.4 0.065 13.5 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1822 PF08852.11 OAG08430.1 - 1.2 8.1 10.5 1.5 7.8 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DASH_Dad2 PF08654.10 OAG08430.1 - 2.5 8.6 11.2 6.3 7.3 11.2 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad2 BRF1 PF07741.13 OAG08430.1 - 3.2 8.1 9.2 0.51 10.7 2.4 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain ALMT PF11744.8 OAG08430.1 - 4.1 6.1 6.5 5.4 5.7 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TTL PF03133.15 OAG08432.1 - 1.9e-53 181.5 0.0 5.3e-53 180.1 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family UPA PF17217.3 OAG08432.1 - 0.0097 15.8 0.0 0.083 12.8 0.0 2.2 3 0 0 3 3 3 1 UPA domain eIF-3c_N PF05470.12 OAG08432.1 - 0.14 10.5 0.1 0.14 10.4 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 OAG08432.1 - 4.2 6.7 8.9 6.2 6.2 8.9 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 OAG08432.1 - 5 5.1 8.7 7.2 4.6 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-primase PF09329.11 OAG08433.1 - 6.2e-18 64.3 1.0 1.1e-17 63.5 1.0 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 OAG08433.1 - 0.027 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.10 OAG08434.1 - 1.1e-39 136.2 0.0 1.1e-39 136.2 0.0 1.8 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 OAG08434.1 - 2.2e-22 79.1 0.0 5.6e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain DUF1682 PF07946.14 OAG08434.1 - 0.0089 15.3 1.5 0.014 14.7 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF1869 PF08956.10 OAG08434.1 - 0.086 12.7 0.1 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) FAP PF07174.11 OAG08435.1 - 0.049 13.1 3.5 0.059 12.8 3.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RTA1 PF04479.13 OAG08436.1 - 2.1e-58 197.4 17.7 2.1e-58 197.4 17.7 1.6 2 0 0 2 2 2 1 RTA1 like protein Lzipper-MIP1 PF14389.6 OAG08437.1 - 0.14 12.5 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Surp PF01805.20 OAG08438.1 - 2.6e-13 49.7 0.0 5.9e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 OAG08438.1 - 0.14 12.0 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_19 PF14559.6 OAG08439.1 - 2.3e-09 37.6 0.0 2.9e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG08439.1 - 0.00011 22.7 6.6 0.00018 22.1 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG08439.1 - 0.00014 21.3 0.7 0.00067 19.1 0.7 2.4 1 1 0 1 1 1 1 MalT-like TPR region Coatomer_E PF04733.14 OAG08439.1 - 0.00066 19.2 0.0 0.00093 18.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_6 PF13174.6 OAG08439.1 - 0.0012 19.3 0.1 1.7 9.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG08439.1 - 0.0047 17.2 0.5 0.21 11.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG08439.1 - 0.043 13.9 3.0 1.5 9.1 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG08439.1 - 0.13 12.7 0.0 0.67 10.5 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG08439.1 - 0.14 13.0 12.0 2.4 9.2 0.0 5.7 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF2457 PF10446.9 OAG08439.1 - 0.47 9.5 2.7 0.7 9.0 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TPR_4 PF07721.14 OAG08439.1 - 2.2 9.1 18.9 1.4 9.8 0.6 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.18 OAG08440.1 - 2.3e-56 190.1 0.1 1.9e-55 187.1 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG08440.1 - 3.5e-49 166.5 0.0 2.5e-48 163.8 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG08440.1 - 1.6e-41 141.2 1.2 2.3e-41 140.8 0.4 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 OAG08440.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF4548 PF15081.6 OAG08441.1 - 0.04 13.8 0.3 0.04 13.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) ECH_1 PF00378.20 OAG08442.1 - 1.9e-70 237.0 0.2 2.2e-70 236.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG08442.1 - 5.2e-32 111.7 0.1 8.1e-29 101.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase KNTase_C PF07827.11 OAG08442.1 - 0.056 13.3 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 KNTase C-terminal domain AMP-binding PF00501.28 OAG08443.1 - 5.8e-82 275.5 0.0 1.1e-81 274.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG08443.1 - 0.00027 21.8 0.0 0.00084 20.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fer4_14 PF13394.6 OAG08443.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain SdpI PF13630.6 OAG08443.1 - 1.3 9.2 7.8 0.2 11.8 2.2 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family Fungal_trans_2 PF11951.8 OAG08444.1 - 0.024 13.5 0.3 0.038 12.8 0.0 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 OAG08445.1 - 4.1e-14 52.9 0.1 5.1e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG08445.1 - 1.9e-10 41.8 5.2 2.3e-10 41.5 5.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG08445.1 - 2.8e-05 23.5 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAG08445.1 - 0.072 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme adh_short PF00106.25 OAG08446.1 - 1.7e-24 86.4 0.1 2e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG08446.1 - 6.4e-15 55.3 0.0 8.7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG08446.1 - 3.8e-10 40.0 0.1 5.2e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG08446.1 - 0.00011 21.5 0.0 0.00014 21.1 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG08446.1 - 0.082 12.4 0.6 0.2 11.1 0.6 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family P53_C PF11619.8 OAG08446.1 - 0.11 12.5 0.2 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain Eno-Rase_NADH_b PF12242.8 OAG08446.1 - 0.29 10.9 1.1 0.42 10.4 0.2 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Tannase PF07519.11 OAG08447.1 - 8.4e-52 176.6 0.0 9.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG08447.1 - 0.045 13.2 0.0 0.081 12.4 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Aldo_ket_red PF00248.21 OAG08448.1 - 4.9e-57 193.4 0.0 6.4e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RING_2 PF13639.6 OAG08449.1 - 4.5e-13 49.3 4.4 7.2e-13 48.6 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG08449.1 - 5.7e-11 42.0 1.8 1e-10 41.2 1.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG08449.1 - 5e-08 32.7 4.6 7.8e-08 32.0 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG08449.1 - 3.4e-07 30.0 3.0 5.6e-07 29.3 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG08449.1 - 3.9e-06 27.0 4.4 1e-05 25.7 4.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG08449.1 - 2.1e-05 24.4 1.7 3.4e-05 23.7 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG08449.1 - 2.6e-05 24.0 4.6 4.5e-05 23.2 4.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG08449.1 - 0.00088 19.1 0.9 0.0014 18.4 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG08449.1 - 0.0043 17.1 0.6 0.0089 16.1 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OAG08449.1 - 0.026 14.3 3.4 0.046 13.5 3.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OAG08449.1 - 0.052 13.6 6.3 0.11 12.6 6.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 OAG08449.1 - 0.29 11.1 3.1 0.52 10.2 3.1 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 OAG08449.1 - 0.33 10.9 3.8 0.28 11.1 1.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 OAG08449.1 - 4.1 7.6 4.8 7.5 6.8 4.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Na_Ca_ex PF01699.24 OAG08450.1 - 1.4e-22 80.2 32.8 6.1e-15 55.5 11.3 3.8 4 2 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 OAG08450.1 - 4.9e-13 49.6 12.8 4.9e-13 49.6 12.8 4.6 5 0 0 5 5 5 1 Inner membrane component domain Cwf_Cwc_15 PF04889.12 OAG08450.1 - 2.3 7.9 16.8 4.9 6.8 16.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4407 PF14362.6 OAG08450.1 - 6.2 6.1 10.5 5.4 6.3 6.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA PF00004.29 OAG08451.1 - 1e-43 148.9 0.0 1.7e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG08451.1 - 4.2e-14 52.1 0.0 1e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAG08451.1 - 9.7e-08 32.3 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAG08451.1 - 6.2e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG08451.1 - 6.5e-07 29.9 0.0 3.9e-05 24.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG08451.1 - 1.5e-05 25.3 0.2 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 OAG08451.1 - 2.1e-05 24.4 2.1 5.5e-05 23.0 2.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 OAG08451.1 - 6.1e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OAG08451.1 - 0.001 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 OAG08451.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 OAG08451.1 - 0.0013 19.3 0.0 0.028 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG08451.1 - 0.0019 18.3 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAG08451.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 OAG08451.1 - 0.007 16.0 0.1 0.024 14.3 0.1 2.0 1 1 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 OAG08451.1 - 0.0074 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 OAG08451.1 - 0.0079 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OAG08451.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAG08451.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OAG08451.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 OAG08451.1 - 0.021 14.5 0.0 0.092 12.4 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.16 OAG08451.1 - 0.026 14.0 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OAG08451.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAG08451.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG08451.1 - 0.038 14.4 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 OAG08451.1 - 0.041 13.9 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain HR1 PF02185.16 OAG08451.1 - 0.048 13.8 0.6 0.11 12.6 0.6 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_25 PF13481.6 OAG08451.1 - 0.071 12.7 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OAG08451.1 - 0.09 11.9 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 OAG08451.1 - 0.17 12.2 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein MFS_1 PF07690.16 OAG08452.1 - 1.9e-20 73.1 34.1 3.5e-15 55.8 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG08452.1 - 2.3e-13 49.8 19.5 1.3e-12 47.4 19.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter NCA2 PF08637.10 OAG08453.1 - 2.3e-103 345.3 0.4 4.2e-103 344.5 0.4 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.22 OAG08453.1 - 2.5e-53 180.0 0.2 4.5e-53 179.2 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG08453.1 - 4.5e-24 85.0 0.2 1.2e-23 83.6 0.2 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG08453.1 - 6.6e-09 35.5 0.1 1.4e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG08453.1 - 0.00027 20.5 0.0 0.00058 19.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CFEM PF05730.11 OAG08455.1 - 1.8e-10 40.8 3.6 7.5e-10 38.8 3.6 2.1 1 0 0 1 1 1 1 CFEM domain Chorismate_bind PF00425.18 OAG08457.1 - 2.4e-74 250.1 0.0 4.6e-74 249.2 0.0 1.5 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 OAG08457.1 - 4.1e-27 95.2 0.0 1e-26 93.9 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OAG08457.1 - 1.7e-15 57.4 0.0 4.5e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OAG08457.1 - 3.5e-07 30.2 0.1 7e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase C26 CN_hydrolase PF00795.22 OAG08458.1 - 1.9e-41 142.1 0.0 2.3e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_3 PF07859.13 OAG08459.1 - 5.6e-43 147.3 0.1 8.1e-43 146.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG08459.1 - 4.8e-06 26.2 0.0 1.2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 OAG08459.1 - 4.4e-05 22.3 0.1 8.8e-05 21.3 0.1 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 OAG08459.1 - 0.00027 20.6 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OAG08459.1 - 0.0054 16.4 0.3 0.05 13.2 0.3 2.0 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.28 OAG08459.1 - 0.017 14.0 0.0 0.058 12.2 0.0 1.7 1 1 0 1 1 1 0 Carboxylesterase family BAAT_C PF08840.11 OAG08459.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 OAG08459.1 - 0.021 14.3 1.6 0.049 13.1 0.1 2.1 3 0 0 3 3 3 0 Esterase PHB depolymerase Lipase_3 PF01764.25 OAG08459.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 OAG08459.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CRAL_TRIO PF00650.20 OAG08460.1 - 3.6e-22 78.8 0.0 5.4e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG08460.1 - 0.00018 21.6 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FMO-like PF00743.19 OAG08462.1 - 9e-16 57.4 0.3 3.7e-15 55.4 0.3 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG08462.1 - 5.2e-14 52.2 0.0 7.1e-12 45.1 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG08462.1 - 6.6e-14 51.9 0.3 3.7e-12 46.1 0.2 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG08462.1 - 2e-10 40.4 0.4 2.3e-07 30.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG08462.1 - 3.9e-07 30.2 0.0 1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG08462.1 - 2.3e-06 27.4 0.2 8.7e-05 22.3 0.0 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG08462.1 - 1.6e-05 25.4 0.1 0.11 13.1 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG08462.1 - 0.0035 17.4 0.1 0.28 11.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAG08462.1 - 0.007 15.5 0.3 0.019 14.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAG08462.1 - 0.011 15.7 0.0 0.078 13.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG08462.1 - 0.02 14.2 0.1 0.045 13.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAG08462.1 - 0.34 9.6 0.7 0.67 8.6 0.7 1.5 1 0 0 1 1 1 0 HI0933-like protein Bud13 PF09736.9 OAG08463.1 - 3.2e-47 160.6 8.8 3.2e-47 160.6 8.8 3.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DNA_binding_1 PF01035.20 OAG08464.1 - 5.7e-24 84.1 0.1 7.6e-24 83.6 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4224 PF13986.6 OAG08464.1 - 0.025 14.5 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) NOA36 PF06524.12 OAG08464.1 - 0.18 11.1 2.0 0.28 10.5 2.0 1.3 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_3 PF07859.13 OAG08466.1 - 2e-42 145.5 0.0 3.2e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OAG08466.1 - 6.7e-05 21.9 0.1 0.00014 20.9 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG08466.1 - 0.037 13.5 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family HET PF06985.11 OAG08467.1 - 1.5e-25 90.2 0.0 3.2e-25 89.2 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glycos_transf_2 PF00535.26 OAG08468.1 - 1.7e-35 122.3 0.0 2.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG08468.1 - 1.9e-12 47.6 0.0 2.3e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG08468.1 - 2.7e-06 27.0 0.0 4.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 OAG08468.1 - 6.6e-06 25.8 0.0 9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OAG08468.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Hydrolase PF00702.26 OAG08469.1 - 3e-05 24.4 0.0 6.3e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG08469.1 - 0.00097 19.3 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG08469.1 - 0.0029 17.6 0.2 0.0095 16.0 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like PEHE PF15275.6 OAG08470.1 - 0.039 14.6 0.5 0.15 12.7 0.5 2.0 1 0 0 1 1 1 0 PEHE domain SURF2 PF05477.11 OAG08470.1 - 0.21 11.3 13.2 0.05 13.3 3.1 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) dCMP_cyt_deam_1 PF00383.23 OAG08471.1 - 4.6e-25 87.4 0.0 6.8e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG08471.1 - 8.5e-19 67.7 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAG08471.1 - 0.0048 17.0 0.8 0.037 14.1 0.2 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC3 PF18771.1 OAG08471.1 - 0.022 14.9 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 SNAD4 PF18750.1 OAG08471.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF742 PF05331.11 OAG08471.1 - 0.12 12.2 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF742) APOBEC4_like PF18774.1 OAG08471.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Cg6151-P PF10233.9 OAG08472.1 - 2e-39 134.4 10.8 2.3e-39 134.2 10.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 OAG08472.1 - 0.12 12.5 8.5 0.22 11.6 8.5 1.4 1 1 0 1 1 1 0 COPI associated protein DUF3784 PF12650.7 OAG08472.1 - 0.5 10.6 9.2 0.35 11.1 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF5592 PF17332.2 OAG08472.1 - 0.56 10.8 3.2 0.33 11.5 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Dpy19 PF10034.9 OAG08472.1 - 0.91 7.6 5.4 1.1 7.3 5.4 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Sdh_cyt PF01127.22 OAG08472.1 - 1 9.4 9.9 0.36 10.9 1.1 2.3 1 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2157 PF09925.9 OAG08472.1 - 3.1 7.6 12.7 20 5.0 12.7 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) CbiN PF02553.15 OAG08472.1 - 5.6 7.0 7.6 0.58 10.2 0.5 2.3 2 0 0 2 2 2 0 Cobalt transport protein component CbiN DUF2721 PF11026.8 OAG08472.1 - 9.1 6.2 14.1 0.78 9.6 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Aim21 PF11489.8 OAG08473.1 - 4.6e-218 726.7 70.1 4.6e-218 726.7 70.1 1.8 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 HMG_CoA_synt_C PF08540.10 OAG08476.1 - 1.7e-105 352.7 0.1 2.3e-105 352.3 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 OAG08476.1 - 2e-96 320.8 0.1 3e-96 320.3 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal COX16 PF14138.6 OAG08477.1 - 4.2e-33 113.7 0.3 5.4e-33 113.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 PI3_PI4_kinase PF00454.27 OAG08478.1 - 2.6e-54 184.7 0.0 5.4e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAG08478.1 - 1e-31 110.4 0.0 1.8e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.13 OAG08478.1 - 7e-27 93.3 1.6 1.4e-26 92.4 0.3 2.4 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 OAG08478.1 - 1.1e-12 47.5 0.0 3.5e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OAG08478.1 - 0.00056 19.9 0.1 0.019 14.9 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) TPR_19 PF14559.6 OAG08478.1 - 0.0029 18.1 4.8 0.0052 17.3 0.0 3.6 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG08478.1 - 0.0077 16.3 2.7 10 6.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAG08478.1 - 0.011 15.0 0.7 0.11 11.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG08478.1 - 0.013 16.2 1.5 3.5 8.7 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG08478.1 - 0.02 14.9 1.3 13 6.1 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Porphobil_deam PF01379.20 OAG08478.1 - 0.076 12.5 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain Coatomer_E PF04733.14 OAG08478.1 - 0.11 11.9 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 Coatomer epsilon subunit Ribosomal_S19 PF00203.21 OAG08479.1 - 1.6e-31 108.0 0.1 3.7e-31 106.9 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S19 Per1 PF04080.13 OAG08480.1 - 7.8e-103 343.7 13.4 9.3e-103 343.4 13.4 1.1 1 0 0 1 1 1 1 Per1-like family BTB PF00651.31 OAG08482.1 - 1.6e-06 28.3 0.1 3.8e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3934 PF13070.6 OAG08482.1 - 0.14 12.7 7.0 0.29 11.6 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) INO80_Ies4 PF08193.11 OAG08483.1 - 0.027 14.5 0.3 0.034 14.1 0.3 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 HA PF03457.14 OAG08484.1 - 0.08 13.3 0.5 0.23 11.8 0.1 2.0 2 0 0 2 2 2 0 Helicase associated domain zf-BED PF02892.15 OAG08484.1 - 0.16 12.0 0.7 11 6.1 0.0 2.9 2 0 0 2 2 2 0 BED zinc finger Sina PF03145.16 OAG08484.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Seven in absentia protein family AAA PF00004.29 OAG08486.1 - 3.8e-62 208.5 0.1 2.3e-43 147.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG08486.1 - 5.2e-14 51.8 1.2 1.8e-07 30.8 0.0 3.3 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OAG08486.1 - 2.9e-12 47.3 1.0 0.0012 19.2 0.5 4.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 OAG08486.1 - 6.8e-12 45.6 0.1 2.2e-06 27.7 0.0 2.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG08486.1 - 1.9e-09 37.9 0.0 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OAG08486.1 - 5.1e-09 36.5 3.2 0.011 16.0 0.0 4.0 2 2 2 4 4 4 3 AAA domain AAA_14 PF13173.6 OAG08486.1 - 7.1e-08 32.6 0.0 0.0027 17.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain Bac_DnaA PF00308.18 OAG08486.1 - 1.1e-07 31.9 0.0 5.6e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.12 OAG08486.1 - 1.7e-07 31.3 0.9 0.013 15.5 0.0 3.6 2 2 1 3 3 3 2 NACHT domain TniB PF05621.11 OAG08486.1 - 3.2e-06 26.7 0.2 0.56 9.6 0.0 4.0 2 2 2 4 4 4 2 Bacterial TniB protein Sigma54_activ_2 PF14532.6 OAG08486.1 - 4.2e-06 26.9 0.0 0.04 14.0 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 OAG08486.1 - 5.4e-06 26.5 1.3 0.017 15.1 0.4 3.7 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 OAG08486.1 - 1.8e-05 24.8 0.0 0.049 13.5 0.0 2.7 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_25 PF13481.6 OAG08486.1 - 1.8e-05 24.4 0.4 1.9 8.0 0.1 3.6 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 OAG08486.1 - 2.8e-05 23.6 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG08486.1 - 4e-05 24.0 0.0 0.51 10.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 OAG08486.1 - 4.3e-05 23.1 0.0 0.26 10.8 0.0 2.9 3 1 0 3 3 3 2 P-loop containing dynein motor region RuvB_N PF05496.12 OAG08486.1 - 0.0001 22.1 0.0 0.0097 15.7 0.0 3.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 OAG08486.1 - 0.00014 21.3 0.3 0.63 9.3 0.0 3.2 2 1 1 3 3 3 1 KaiC AAA_33 PF13671.6 OAG08486.1 - 0.00031 20.9 0.0 0.21 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG08486.1 - 0.00049 20.4 0.0 0.044 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAG08486.1 - 0.0014 17.9 0.0 0.83 8.9 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin TIP49 PF06068.13 OAG08486.1 - 0.0015 17.8 0.0 0.005 16.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 OAG08486.1 - 0.002 17.9 0.0 0.06 13.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain CDC48_N PF02359.18 OAG08486.1 - 0.0034 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activat PF00158.26 OAG08486.1 - 0.0041 16.9 0.0 4.6 6.9 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain SRPRB PF09439.10 OAG08486.1 - 0.0051 16.3 0.1 0.23 10.9 0.0 2.8 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.17 OAG08486.1 - 0.0071 16.1 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein BMFP PF04380.13 OAG08486.1 - 0.0075 16.7 1.7 0.041 14.4 0.1 2.8 3 0 0 3 3 2 1 Membrane fusogenic activity TMF_TATA_bd PF12325.8 OAG08486.1 - 0.0089 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF815 PF05673.13 OAG08486.1 - 0.01 15.0 0.0 3.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAG08486.1 - 0.012 16.2 0.0 1 9.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 OAG08486.1 - 0.013 16.0 0.0 0.84 10.1 0.0 3.1 3 0 0 3 3 3 0 ABC transporter ATP-synt_ab PF00006.25 OAG08486.1 - 0.02 14.6 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 OAG08486.1 - 0.022 14.7 0.2 13 5.6 0.0 3.4 2 2 1 3 3 3 0 NTPase KAP_NTPase PF07693.14 OAG08486.1 - 0.024 13.9 0.2 1.1 8.4 0.1 2.5 2 1 1 3 3 3 0 KAP family P-loop domain DAP3 PF10236.9 OAG08486.1 - 0.029 13.5 0.0 0.58 9.3 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 OAG08486.1 - 0.032 13.4 0.0 4.1 6.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Vps4_C PF09336.10 OAG08486.1 - 0.048 13.7 0.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain TsaE PF02367.17 OAG08486.1 - 0.072 13.1 0.0 5.8 6.9 0.0 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OAG08486.1 - 0.11 12.4 0.0 2.7 7.9 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_2 PF12756.7 OAG08487.1 - 0.0004 20.7 3.2 0.045 14.1 0.0 3.3 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OAG08487.1 - 0.31 11.6 5.6 0.79 10.3 1.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG08487.1 - 1.5 9.8 8.8 0.47 11.4 0.5 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 OAG08487.1 - 8 6.5 5.1 25 4.9 0.1 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Glutaminase PF04960.15 OAG08488.1 - 9.3e-113 376.2 0.1 1.1e-112 375.9 0.1 1.1 1 0 0 1 1 1 1 Glutaminase HET PF06985.11 OAG08489.1 - 3.6e-06 27.4 0.3 0.075 13.4 0.3 2.3 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG08490.1 - 0.009 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1729 PF08354.10 OAG08491.1 - 1.5e-161 537.2 0.0 2.9e-161 536.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 OAG08491.1 - 6.6e-92 308.4 0.1 2.8e-90 303.1 0.0 3.3 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 OAG08491.1 - 2.2e-50 170.3 0.0 5.3e-50 169.0 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 OAG08491.1 - 4.7e-38 131.3 0.0 1.3e-37 129.8 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 OAG08491.1 - 1.6e-36 124.6 0.0 3.1e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 OAG08491.1 - 1.4e-35 122.1 0.2 7.8e-35 119.7 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 OAG08491.1 - 5.1e-24 84.9 0.0 1.5e-23 83.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 OAG08491.1 - 0.032 13.6 0.3 0.58 9.5 0.3 2.6 1 1 0 1 1 1 0 Nitronate monooxygenase Phage-MuB_C PF09077.11 OAG08491.1 - 0.17 11.8 0.1 9.4 6.2 0.2 3.1 2 0 0 2 2 2 0 Mu B transposition protein, C terminal FAS_I_H PF18314.1 OAG08493.1 - 1.5e-79 266.3 0.0 4e-79 265.0 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAG08493.1 - 6.4e-77 257.4 0.0 1.5e-76 256.3 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 OAG08493.1 - 1.6e-21 77.1 0.0 3.3e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 OAG08493.1 - 5.8e-18 65.1 0.1 1.4e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 OAG08493.1 - 2.2e-11 43.8 0.0 2.7e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 OAG08493.1 - 2.5e-06 27.1 0.0 5.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG08493.1 - 0.012 15.5 0.0 0.042 13.8 0.0 2.0 1 0 0 1 1 1 0 KR domain HET PF06985.11 OAG08494.1 - 0.066 13.6 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAG08495.1 - 4.1e-21 75.9 0.1 4.9e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DAO PF01266.24 OAG08496.1 - 2.4e-43 149.1 0.6 2.8e-43 148.9 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG08496.1 - 0.00013 21.3 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG08496.1 - 0.00053 20.2 0.1 0.0035 17.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG08496.1 - 0.0023 17.1 0.1 0.013 14.6 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAG08496.1 - 0.0041 17.1 0.1 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 OAG08496.1 - 0.073 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 OAG08496.1 - 0.075 11.9 0.0 0.75 8.6 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AA_permease PF00324.21 OAG08497.1 - 5.5e-78 262.7 42.4 6.7e-78 262.4 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG08497.1 - 9.9e-23 80.6 46.6 1.2e-22 80.4 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 OAG08498.1 - 2.4e-69 234.3 0.0 2.7e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MetW PF07021.12 OAG08499.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Glucosamine_iso PF01182.20 OAG08500.1 - 2.2e-20 73.5 0.0 3.7e-20 72.8 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MFS_1 PF07690.16 OAG08501.1 - 4.2e-10 39.1 36.7 4.2e-10 39.1 36.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG08501.1 - 4.2e-10 39.5 8.2 4.2e-10 39.5 8.2 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 OAG08501.1 - 0.00059 18.8 6.5 0.00059 18.8 6.5 1.8 2 0 0 2 2 2 1 MFS_1 like family Hexokinase_2 PF03727.16 OAG08502.1 - 1.4e-58 198.2 0.0 1.9e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG08502.1 - 9.3e-46 156.2 0.0 1.6e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase FtsA PF14450.6 OAG08502.1 - 0.17 12.3 0.0 0.46 10.9 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsA NDT80_PhoG PF05224.12 OAG08505.1 - 1.7e-34 119.7 0.0 3e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.21 OAG08506.1 - 2e-69 234.4 0.0 2.7e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 OAG08506.1 - 2.5e-06 27.7 0.0 1.8e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 OAG08506.1 - 0.00081 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Amidohydro_1 PF01979.20 OAG08507.1 - 1.2e-17 64.2 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG08507.1 - 1.1e-12 48.1 1.7 1e-10 41.7 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Ras PF00071.22 OAG08508.1 - 2.6e-41 140.9 0.0 2e-40 138.0 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG08508.1 - 2.5e-33 114.8 0.1 3.9e-33 114.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG08508.1 - 6.5e-13 48.5 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG08508.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG08508.1 - 0.00051 20.5 0.0 0.00093 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 OAG08508.1 - 0.0018 17.6 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAG08508.1 - 0.0047 16.4 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OAG08508.1 - 0.014 15.1 0.1 0.66 9.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OAG08508.1 - 0.048 13.4 0.4 0.11 12.2 0.0 1.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 OAG08508.1 - 0.067 13.5 0.2 0.37 11.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OAG08508.1 - 0.068 13.1 0.2 0.29 11.0 0.2 2.1 2 1 1 3 3 3 0 RsgA GTPase FMN_dh PF01070.18 OAG08509.1 - 3.5e-122 407.8 0.3 4.2e-122 407.5 0.3 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG08509.1 - 3.3e-24 84.8 0.1 6.7e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG08509.1 - 3.2e-08 33.1 0.0 5.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG08509.1 - 2.8e-05 23.3 1.2 9.5e-05 21.6 0.2 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG08509.1 - 0.0002 20.9 0.1 0.00028 20.4 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase G3P_antiterm PF04309.12 OAG08509.1 - 0.00072 19.0 0.0 0.88 9.0 0.0 2.4 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 OAG08509.1 - 0.0022 17.5 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 OAG08509.1 - 0.0057 16.0 0.1 0.67 9.2 0.1 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Cytotoxic PF09000.10 OAG08509.1 - 0.066 13.6 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Cytotoxic CRAL_TRIO PF00650.20 OAG08510.1 - 2.2e-11 43.7 0.0 5e-11 42.6 0.0 1.6 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG08510.1 - 4.9e-06 26.6 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG08510.1 - 0.14 12.3 0.0 0.51 10.5 0.0 1.9 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain RRM_1 PF00076.22 OAG08511.1 - 3e-06 27.0 0.0 5.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 OAG08511.1 - 0.00076 19.8 0.3 0.0012 19.1 0.3 1.4 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding FGGY_C PF02782.16 OAG08513.1 - 4.7e-50 170.1 0.4 7.5e-50 169.4 0.4 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG08513.1 - 1.4e-24 87.0 1.8 1.3e-22 80.5 1.8 3.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OAG08513.1 - 0.00014 21.4 0.1 0.00041 19.9 0.0 1.8 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family zf-C2H2_9 PF16293.5 OAG08513.1 - 0.034 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) RRM_1 PF00076.22 OAG08514.1 - 2.6e-10 40.0 0.0 5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG08514.1 - 9.6e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG08514.1 - 0.00057 19.8 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG08514.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif HTH_Tnp_1 PF01527.20 OAG08514.1 - 0.16 12.3 0.5 6.3 7.2 0.0 2.7 2 1 0 2 2 2 0 Transposase Cutinase PF01083.22 OAG08515.1 - 8e-36 123.7 0.0 9.3e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG08515.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 OAG08515.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 OAG08515.1 - 0.2 11.4 0.0 0.28 11.0 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase ParA PF10609.9 OAG08516.1 - 5.6e-93 310.9 0.0 6.6e-93 310.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAG08516.1 - 1.6e-08 34.6 0.0 7.5e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAG08516.1 - 4.9e-06 26.6 0.0 1.4e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OAG08516.1 - 2.5e-05 23.6 0.5 0.0011 18.2 0.6 2.3 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 OAG08516.1 - 0.0048 16.8 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG08516.1 - 0.021 14.8 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OAG08516.1 - 0.048 13.4 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 OAG08516.1 - 0.062 12.6 0.0 0.17 11.1 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 OAG08516.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 OAG08516.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 OAG08516.1 - 0.094 12.1 0.0 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Rad17 PF03215.15 OAG08516.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 OAG08516.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 OAG08516.1 - 0.2 12.0 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 OAG08516.1 - 0.21 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mlh1_C PF16413.5 OAG08517.1 - 3.4e-100 334.9 0.0 5.7e-100 334.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OAG08517.1 - 5.4e-34 116.4 0.1 9.3e-34 115.7 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG08517.1 - 3.6e-14 52.7 0.0 7.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG08517.1 - 1.7e-07 31.7 0.0 3.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF687 PF05095.12 OAG08518.1 - 0.076 11.5 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) DUF3533 PF12051.8 OAG08519.1 - 7.5e-112 374.0 16.2 8.5e-112 373.8 16.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1746 PF08508.10 OAG08519.1 - 0.15 12.4 1.9 0.34 11.3 1.9 1.6 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1746) UbiA PF01040.18 OAG08520.1 - 1.5e-20 73.6 14.5 2.3e-20 73.0 14.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2197 PF09963.9 OAG08520.1 - 0.12 12.6 0.8 5.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Fungus-induced PF10917.8 OAG08520.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Fungus-induced protein Nipped-B_C PF12830.7 OAG08521.1 - 3.3e-40 138.1 1.6 2.2e-37 128.9 0.1 3.4 2 1 0 2 2 2 2 Sister chromatid cohesion C-terminus Cnd1 PF12717.7 OAG08521.1 - 0.00092 19.3 1.4 0.083 12.9 0.0 3.5 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG08521.1 - 0.046 14.2 0.3 54 4.4 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 OAG08521.1 - 0.085 13.2 0.5 1.3 9.4 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat Cohesin_HEAT PF12765.7 OAG08521.1 - 0.099 13.0 0.1 0.33 11.3 0.1 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Phospholamban PF04272.14 OAG08521.1 - 0.16 11.5 0.3 0.58 9.7 0.2 2.1 2 0 0 2 2 2 0 Phospholamban TFIIS_C PF01096.18 OAG08522.1 - 1e-15 57.2 4.2 1e-15 57.2 4.2 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OAG08522.1 - 7e-05 22.6 1.4 7e-05 22.6 1.4 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 OAG08522.1 - 0.0099 15.7 0.9 0.0099 15.7 0.9 2.3 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 OAG08522.1 - 0.026 14.2 12.3 1.9 8.3 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_7 PF02591.15 OAG08522.1 - 0.058 13.6 2.1 31 4.9 0.1 3.5 3 0 0 3 3 3 0 C4-type zinc ribbon domain PHD_3 PF13922.6 OAG08522.1 - 0.14 12.6 0.7 0.14 12.6 0.7 3.0 2 2 1 3 3 3 0 PHD domain of transcriptional enhancer, Asx zf-3CxxC_2 PF17180.4 OAG08522.1 - 0.17 12.6 11.9 4.3 8.1 0.4 3.1 2 1 1 3 3 3 0 Zinc-binding domain zf-B_box PF00643.24 OAG08522.1 - 1.2 9.3 6.8 53 4.1 0.1 3.2 3 0 0 3 3 3 0 B-box zinc finger DZR PF12773.7 OAG08522.1 - 1.5 8.9 13.1 1.1e+02 2.9 13.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 OAG08522.1 - 9.2 6.1 15.4 20 5.0 0.0 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain HEAT_2 PF13646.6 OAG08523.1 - 1.7e-28 98.8 7.3 6.9e-14 52.0 0.8 4.0 2 2 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 OAG08523.1 - 8e-20 69.5 0.2 0.011 16.3 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 OAG08523.1 - 6.5e-09 35.3 1.3 0.53 10.7 0.0 6.0 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 OAG08523.1 - 0.0016 18.9 8.2 6.6 7.4 0.0 5.5 4 2 3 7 7 7 3 HEAT-like repeat Arm PF00514.23 OAG08523.1 - 0.029 14.4 0.1 2.3 8.4 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PUB_1 PF18486.1 OAG08523.1 - 0.07 13.0 0.3 0.23 11.3 0.3 1.9 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain MCM2_N PF12619.8 OAG08524.1 - 0.0089 16.3 3.4 0.017 15.4 3.4 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance protein 2 PEP_mutase PF13714.6 OAG08525.1 - 1.6e-61 207.8 3.4 1.8e-61 207.6 3.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase BRCT PF00533.26 OAG08525.1 - 0.068 13.6 0.0 0.8 10.1 0.0 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Surfac_D-trimer PF09006.11 OAG08526.1 - 0.0033 17.3 0.2 0.012 15.5 0.2 1.9 1 0 0 1 1 1 1 Lung surfactant protein D coiled-coil trimerisation IBP39 PF11422.8 OAG08526.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Vps23_core PF09454.10 OAG08526.1 - 0.026 14.5 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Vps23 core domain DUF2935 PF11155.8 OAG08526.1 - 0.17 12.2 2.9 0.84 10.0 2.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Spc7 PF08317.11 OAG08526.1 - 1.7 7.4 26.9 3.6 6.4 18.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein PspB PF06667.12 OAG08526.1 - 7.9 6.6 9.5 0.73 9.9 0.2 3.3 2 1 1 3 3 3 0 Phage shock protein B Atg14 PF10186.9 OAG08526.1 - 8.1 5.4 22.5 4 6.4 5.5 2.8 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Glyco_hydro_7 PF00840.20 OAG08527.1 - 6.4e-199 661.1 20.9 7.3e-199 660.9 20.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 RTA1 PF04479.13 OAG08528.1 - 3.7e-42 144.3 9.8 8.1e-42 143.2 9.8 1.5 1 1 0 1 1 1 1 RTA1 like protein DUF373 PF04123.13 OAG08528.1 - 0.15 11.4 7.2 0.09 12.2 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Cpn60_TCP1 PF00118.24 OAG08529.1 - 9.1e-156 519.3 16.3 1e-155 519.1 16.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 OAG08530.1 - 1.1e-23 83.3 0.2 2.2e-23 82.2 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 OAG08530.1 - 1.5e-17 64.2 0.0 2.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG08530.1 - 3.6e-17 62.3 0.0 8.3e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain C_Hendra PF16821.5 OAG08530.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses MFS_1 PF07690.16 OAG08531.1 - 1.9e-28 99.4 25.6 1.9e-28 99.4 25.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 OAG08532.1 - 8.3e-08 33.1 1.0 3.8e-07 30.9 1.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG08532.1 - 1.8e-06 27.8 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG08532.1 - 0.0035 16.7 0.0 0.04 13.2 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FA_hydroxylase PF04116.13 OAG08533.1 - 7.3e-19 68.4 2.2 7.3e-19 68.4 2.2 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 OAG08534.1 - 1.9e-38 131.4 0.3 1.9e-38 131.4 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e GNAT_acetyltr_2 PF13718.6 OAG08534.1 - 0.048 13.1 0.2 0.067 12.6 0.2 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 KOW PF00467.29 OAG08534.1 - 0.082 12.9 0.4 0.25 11.3 0.3 1.9 1 1 1 2 2 2 0 KOW motif Proteasom_Rpn13 PF04683.13 OAG08535.1 - 5e-25 87.9 0.0 8e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 OAG08535.1 - 1.3e-10 41.5 0.1 2.3e-09 37.4 0.1 2.2 1 1 0 1 1 1 1 UCH-binding domain Syja_N PF02383.18 OAG08536.1 - 2.3e-77 260.5 0.9 3.5e-77 259.8 0.1 1.8 2 0 0 2 2 2 1 SacI homology domain Hemerythrin PF01814.23 OAG08536.1 - 6.9e-11 42.9 2.8 1.7e-10 41.6 2.8 1.7 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Dcc1 PF09724.9 OAG08537.1 - 8e-35 120.7 0.0 9.9e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RhoGEF PF00621.20 OAG08538.1 - 1.6e-21 77.4 0.0 4.8e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain Nod1 PF17114.5 OAG08538.1 - 1e-06 29.0 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 DUF3507 PF12015.8 OAG08538.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DivIC PF04977.15 OAG08538.1 - 0.29 10.9 1.8 1.2 8.9 1.8 2.1 1 0 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.12 OAG08538.1 - 0.68 10.0 2.1 3.2 7.8 0.7 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S10 PF00450.22 OAG08540.1 - 5.7e-78 263.2 0.7 8.6e-78 262.6 0.7 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Response_reg PF00072.24 OAG08541.1 - 1.3e-15 57.6 0.0 3.6e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG08541.1 - 2e-14 54.0 0.1 4.3e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG08541.1 - 1.2e-09 38.1 0.1 4.4e-09 36.2 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OAG08541.1 - 0.0054 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SRR1 PF07985.12 OAG08543.1 - 2.3e-07 30.8 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SRR1 TPR_2 PF07719.17 OAG08544.1 - 1.4 9.2 8.2 0.68 10.2 1.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG08545.1 - 1.5e-05 24.8 0.6 0.0037 17.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG08545.1 - 0.00025 21.2 2.0 0.00048 20.4 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG08545.1 - 0.00062 19.5 5.5 0.0046 16.7 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG08545.1 - 0.044 14.4 1.2 0.12 13.1 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG08545.1 - 0.046 13.9 1.2 0.12 12.6 0.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG08545.1 - 0.81 10.7 4.2 11 7.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Radical_SAM PF04055.21 OAG08546.1 - 1.2e-11 45.2 0.0 4.3e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 OAG08546.1 - 4.3e-05 23.8 0.0 7.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAG08546.1 - 0.047 13.8 0.3 0.14 12.3 0.2 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain But2 PF09792.9 OAG08547.1 - 3.3e-17 63.2 0.0 4.8e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ADH_zinc_N PF00107.26 OAG08548.1 - 7.1e-11 42.2 0.1 1.3e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG08548.1 - 1.7e-09 37.5 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG08548.1 - 4.5e-06 27.7 0.1 1.1e-05 26.5 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 OAG08548.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LPMO_10 PF03067.15 OAG08549.1 - 1.6e-11 45.2 0.3 2.3e-11 44.7 0.3 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Oxidored_FMN PF00724.20 OAG08550.1 - 5e-44 151.0 0.0 6.2e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sirohm_synth_C PF14823.6 OAG08552.1 - 0.094 12.4 0.1 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Caleosin PF05042.13 OAG08553.1 - 0.058 13.3 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Caleosin related protein Glyco_hydro_11 PF00457.17 OAG08554.1 - 7.8e-66 221.1 7.6 9e-66 220.9 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Acyl-CoA_dh_1 PF00441.24 OAG08555.1 - 1.7e-31 109.5 3.2 1.7e-31 109.5 3.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG08555.1 - 8.7e-21 73.9 0.0 1.7e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG08555.1 - 3.2e-19 69.7 0.2 7.8e-19 68.4 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG08555.1 - 3.3e-14 53.3 7.2 1.3e-13 51.4 4.4 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Amino_oxidase PF01593.24 OAG08557.1 - 6.1e-43 147.7 0.0 1.2e-42 146.8 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG08557.1 - 1.5e-06 28.3 0.0 4.5e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG08557.1 - 0.022 14.0 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 OAG08557.1 - 0.057 12.6 0.0 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribonuc_L-PSP PF01042.21 OAG08558.1 - 4.6e-31 107.4 0.0 7.2e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2905 PF11146.8 OAG08558.1 - 0.11 12.7 0.2 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) Glyco_hydro_61 PF03443.14 OAG08559.1 - 1.3e-47 162.4 0.0 1.5e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 OAG08560.1 - 2.5e-16 59.6 17.9 2.5e-16 59.6 17.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG08560.1 - 3.2e-16 59.4 1.3 3.2e-16 59.4 1.3 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 OATP PF03137.20 OAG08560.1 - 0.014 13.8 8.0 0.076 11.3 0.2 2.6 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OAG08560.1 - 0.41 9.5 23.7 0.015 14.2 5.5 3.1 3 1 1 4 4 4 0 Sugar (and other) transporter DUF3938 PF13074.6 OAG08560.1 - 0.49 10.7 7.1 0.11 12.7 0.6 2.9 3 2 0 3 3 3 0 Protein of unknown function (DUF3938) Sugar_tr PF00083.24 OAG08562.1 - 7.7e-75 252.5 23.0 8.8e-75 252.3 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG08562.1 - 8.1e-14 51.3 25.4 8.1e-14 51.3 25.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG08562.1 - 1.4e-06 27.2 11.5 0.00088 17.9 2.2 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAG08562.1 - 8.5e-06 24.9 8.7 5.4e-05 22.2 3.9 2.3 2 0 0 2 2 2 2 MFS_1 like family DUF2301 PF10063.9 OAG08562.1 - 0.026 15.0 1.2 7.2 7.1 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) IDO PF01231.18 OAG08565.1 - 1.3e-41 142.8 0.0 3.2e-41 141.5 0.0 1.6 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase GTP_EFTU PF00009.27 OAG08565.1 - 1.1e-17 64.3 0.0 1.9e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAG08565.1 - 5.6e-09 36.3 1.8 2.7e-08 34.1 1.5 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 OAG08565.1 - 0.00024 21.4 0.0 0.00052 20.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAG08565.1 - 0.085 12.9 0.1 0.22 11.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG08565.1 - 0.12 12.3 0.2 6.2 6.7 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OAG08565.1 - 0.19 11.5 0.7 2.3 8.0 0.1 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_ligase PF09414.10 OAG08566.1 - 6.4e-09 36.3 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase LisH PF08513.11 OAG08566.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 LisH SnoaL PF07366.12 OAG08569.1 - 0.00015 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase adh_short_C2 PF13561.6 OAG08570.1 - 5.7e-56 189.7 0.1 6.6e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG08570.1 - 5.4e-45 153.3 0.2 6.8e-45 152.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG08570.1 - 1.6e-12 47.7 0.1 2.7e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG08570.1 - 0.036 13.1 0.1 0.065 12.2 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_3 PF13738.6 OAG08571.1 - 1.2e-16 60.8 0.0 2.6e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG08571.1 - 3.1e-14 52.9 0.0 2.2e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG08571.1 - 3.8e-13 49.3 0.0 3.2e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 OAG08571.1 - 3.6e-11 42.2 0.0 1.5e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG08571.1 - 6.9e-06 26.2 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG08571.1 - 1.3e-05 24.6 0.4 4.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG08571.1 - 9.5e-05 22.1 0.1 0.009 15.6 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG08571.1 - 0.0031 18.1 0.3 3.5 8.2 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG08571.1 - 0.0032 17.5 0.1 0.075 13.0 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG08571.1 - 0.0059 15.3 0.0 0.62 8.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OAG08571.1 - 0.1 11.9 0.5 1 8.6 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 OAG08572.1 - 1.8e-09 37.0 0.4 5.9e-09 35.3 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG08572.1 - 0.0002 21.4 14.7 0.00041 20.4 14.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RicinB_lectin_2 PF14200.6 OAG08573.1 - 3.7e-05 24.4 0.9 0.086 13.6 1.2 2.5 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Amidohydro_2 PF04909.14 OAG08574.1 - 1.6e-28 100.3 0.1 2.6e-28 99.7 0.1 1.3 1 1 0 1 1 1 1 Amidohydrolase CoA_transf_3 PF02515.17 OAG08575.1 - 9.5e-41 140.1 0.0 7.8e-38 130.5 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III Spidroin_N PF16763.5 OAG08575.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term DnaB_bind PF10410.9 OAG08575.1 - 0.084 13.1 0.0 0.31 11.2 0.0 2.0 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Dioxygenase_C PF00775.21 OAG08576.1 - 2.8e-44 150.7 0.0 3.7e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG08576.1 - 6.8e-29 99.5 0.1 1.2e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAG08576.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain SpaA PF17802.1 OAG08576.1 - 0.054 13.8 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 Prealbumin-like fold domain FAD_binding_3 PF01494.19 OAG08577.1 - 3.2e-16 59.5 0.0 6.7e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG08577.1 - 1.6e-08 34.6 0.6 4e-08 33.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG08577.1 - 1.9e-07 31.0 4.4 3.8e-07 30.0 3.9 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG08577.1 - 2.7e-07 30.1 0.0 5.5e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG08577.1 - 7.1e-06 25.4 2.2 0.00023 20.4 1.7 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAG08577.1 - 1.6e-05 25.4 0.3 4.4e-05 24.0 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG08577.1 - 0.00025 20.5 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG08577.1 - 0.00046 19.6 0.0 0.0021 17.4 0.1 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG08577.1 - 0.0006 19.0 0.1 0.00078 18.6 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG08577.1 - 0.0071 15.1 0.8 0.011 14.5 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAG08577.1 - 0.0083 15.3 1.3 0.013 14.6 1.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 OAG08577.1 - 0.012 15.5 1.0 0.023 14.6 1.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG08577.1 - 0.014 14.7 0.3 0.025 13.9 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OAG08577.1 - 0.042 13.5 0.9 0.14 11.8 0.8 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAG08577.1 - 0.048 12.9 0.6 0.1 11.8 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 OAG08577.1 - 0.056 13.4 0.4 0.098 12.6 0.4 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 OAG08577.1 - 0.14 12.0 0.5 0.27 11.1 0.5 1.4 1 0 0 1 1 1 0 Rossmann-like domain Trp_halogenase PF04820.14 OAG08577.1 - 0.15 10.8 0.9 1.9 7.3 0.7 2.1 2 0 0 2 2 2 0 Tryptophan halogenase MFAP1 PF06991.11 OAG08580.1 - 4.6e-68 229.3 31.3 4.6e-68 229.3 31.3 2.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Serglycin PF04360.12 OAG08580.1 - 0.00015 21.7 4.5 0.00032 20.7 4.5 1.5 1 0 0 1 1 1 1 Serglycin Cwf_Cwc_15 PF04889.12 OAG08580.1 - 0.0024 17.7 17.1 0.0024 17.7 17.1 2.7 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein AF-4 PF05110.13 OAG08580.1 - 1 7.4 25.6 1.6 6.7 25.1 1.5 1 1 0 1 1 1 0 AF-4 proto-oncoprotein Barttin PF15462.6 OAG08580.1 - 4.5 7.0 10.7 6.2 6.5 1.1 3.0 3 0 0 3 3 3 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) AltA1 PF16541.5 OAG08581.1 - 1.7e-11 44.9 0.0 2.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Fungal_trans PF04082.18 OAG08582.1 - 4.6e-07 29.1 0.1 8.2e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 OAG08583.1 - 5.5e-07 29.4 0.1 1.4e-05 24.9 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.18 OAG08584.1 - 6.2e-18 64.8 0.9 2.7e-17 62.7 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAG08585.1 - 5.6e-59 199.5 0.3 8e-59 199.0 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG08585.1 - 1.7e-44 151.6 1.1 2.4e-44 151.2 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DLH PF01738.18 OAG08585.1 - 1.1e-18 67.6 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF4092 PF13322.6 OAG08585.1 - 0.053 13.4 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) MFS_1 PF07690.16 OAG08586.1 - 8.2e-34 117.1 30.8 1.1e-33 116.7 30.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG08586.1 - 1.2e-05 24.3 16.8 7.1e-05 21.8 14.6 2.0 1 1 1 2 2 2 1 MFS_1 like family Methyltransf_16 PF10294.9 OAG08587.1 - 1.9e-18 66.8 0.0 2.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG08587.1 - 6.3e-05 22.9 0.0 8.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG08587.1 - 0.0035 16.8 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.17 OAG08587.1 - 0.0055 15.9 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_25 PF13649.6 OAG08587.1 - 0.008 16.9 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 OAG08587.1 - 0.014 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cons_hypoth95 PF03602.15 OAG08587.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Copper-fist PF00649.18 OAG08588.1 - 2e-16 59.2 3.3 4.7e-16 58.0 3.3 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain SUN PF03856.13 OAG08590.1 - 2.2e-76 256.6 8.5 2.9e-76 256.2 8.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DEAD PF00270.29 OAG08591.1 - 1.2e-32 113.1 0.0 5.4e-32 111.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG08591.1 - 4.9e-25 88.0 0.0 1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG08591.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAG08591.1 - 0.068 13.4 0.5 1.5 9.1 0.3 2.9 2 1 0 2 2 2 0 AAA domain DUF202 PF02656.15 OAG08592.1 - 2.7e-23 82.2 2.0 1.1e-22 80.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Anp1 PF03452.14 OAG08593.1 - 4.5e-108 360.6 0.0 5.3e-108 360.4 0.0 1.0 1 0 0 1 1 1 1 Anp1 Myelin_MBP PF01669.17 OAG08593.1 - 0.011 16.3 0.2 0.011 16.3 0.2 1.8 2 0 0 2 2 2 0 Myelin basic protein Glycos_transf_2 PF00535.26 OAG08593.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Sigma70_ner PF04546.13 OAG08595.1 - 0.11 12.4 1.1 1.4 8.8 0.1 2.8 2 1 0 2 2 2 0 Sigma-70, non-essential region DUF4795 PF16043.5 OAG08595.1 - 0.11 12.1 2.9 29 4.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Cupin_1 PF00190.22 OAG08596.1 - 9.2e-14 51.3 0.0 1.4e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG08596.1 - 0.00057 19.6 0.2 0.0084 15.8 0.1 2.5 3 0 0 3 3 3 1 Cupin domain ATG22 PF11700.8 OAG08597.1 - 4.6e-164 546.6 1.2 5.2e-164 546.4 1.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAG08597.1 - 0.75 8.6 53.2 0.051 12.5 8.3 3.3 3 1 1 4 4 4 0 Major Facilitator Superfamily Pro_isomerase PF00160.21 OAG08600.1 - 3.7e-45 154.0 0.1 1e-44 152.6 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 OAG08600.1 - 2.4e-05 24.4 0.1 8.3e-05 22.7 0.1 1.9 1 1 1 2 2 2 1 U-box domain zf-NOSIP PF15906.5 OAG08600.1 - 0.0032 17.6 0.0 0.0087 16.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF1180 PF06679.12 OAG08600.1 - 2.5 8.5 5.9 27 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ADH_zinc_N PF00107.26 OAG08601.1 - 0.0011 19.0 0.0 0.0033 17.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1840 PF08895.11 OAG08603.1 - 0.19 12.1 5.3 0.065 13.6 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Macoilin PF09726.9 OAG08603.1 - 2.2 6.7 8.0 3.4 6.1 8.0 1.2 1 0 0 1 1 1 0 Macoilin family CCDC84 PF14968.6 OAG08603.1 - 2.4 7.7 7.9 0.27 10.8 3.6 1.6 2 0 0 2 2 2 0 Coiled coil protein 84 TFIIA PF03153.13 OAG08603.1 - 2.4 8.1 12.2 3 7.7 12.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 OAG08603.1 - 4.9 7.8 20.3 0.14 12.8 12.8 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ADH_zinc_N PF00107.26 OAG08604.1 - 8.5e-26 90.5 0.1 1.3e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG08604.1 - 7.5e-23 80.5 5.1 1.5e-22 79.5 3.4 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG08604.1 - 4.2e-08 34.3 0.0 7.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG08604.1 - 0.017 14.6 0.7 0.028 13.9 0.7 1.4 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_4 PF01565.23 OAG08605.1 - 3.3e-21 75.5 0.0 5.6e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG08605.1 - 2.9e-12 46.7 0.0 4.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG08606.1 - 5.1e-13 48.9 0.0 7.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Dak1 PF02733.17 OAG08608.1 - 1.5e-106 355.8 1.6 1.9e-106 355.5 1.6 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAG08608.1 - 8.7e-47 159.2 0.0 1.7e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.22 OAG08609.1 - 3.4e-18 65.1 0.1 4.7e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain GATA PF00320.27 OAG08610.1 - 0.00034 20.2 6.8 0.037 13.6 1.3 2.6 2 0 0 2 2 2 2 GATA zinc finger Zn_clus PF00172.18 OAG08610.1 - 0.0023 18.0 10.0 0.0023 18.0 10.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med2 PF11214.8 OAG08611.1 - 0.021 15.0 0.4 0.036 14.2 0.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 RRM_1 PF00076.22 OAG08612.1 - 4.6e-59 196.2 0.1 7.5e-22 76.9 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG08612.1 - 3.8e-11 42.7 0.0 0.0021 17.9 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_5 PF13893.6 OAG08612.1 - 8.7e-09 35.0 0.0 0.05 13.2 0.0 4.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG08612.1 - 0.00013 21.9 0.0 6.5 6.8 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAG08612.1 - 0.00017 21.6 0.1 0.71 10.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 OAG08612.1 - 0.00028 21.0 0.0 0.1 12.8 0.0 2.7 3 0 0 3 3 3 1 RRM-like domain SET_assoc PF11767.8 OAG08612.1 - 0.0028 17.3 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 OAG08612.1 - 0.0056 16.7 0.6 0.98 9.5 0.1 3.0 4 0 0 4 4 4 1 Limkain b1 Cas_Cas2CT1978 PF09707.10 OAG08612.1 - 0.022 14.8 0.0 9.9 6.3 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) PHM7_cyt PF14703.6 OAG08612.1 - 0.03 14.5 0.1 6.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF1987 PF09345.10 OAG08612.1 - 0.18 11.5 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) ZinT PF09223.11 OAG08612.1 - 0.2 11.5 0.7 1 9.2 0.0 2.3 2 1 1 3 3 3 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment OB_RNB PF08206.11 OAG08612.1 - 0.26 11.0 2.4 28 4.5 0.2 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain p450 PF00067.22 OAG08613.1 - 1.6e-72 244.7 0.0 1.9e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arrestin_N PF00339.29 OAG08616.1 - 2.1e-07 31.1 0.0 2.8e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OAG08616.1 - 0.036 13.2 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Rgp1 CRCB PF02537.15 OAG08619.1 - 0.056 13.8 0.1 0.071 13.4 0.1 1.3 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) Zip PF02535.22 OAG08620.1 - 6.6e-59 199.8 2.6 1.1e-58 199.1 2.6 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Nop16 PF09420.10 OAG08621.1 - 3e-61 207.1 7.0 3.5e-61 206.9 7.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Abhydrolase_1 PF00561.20 OAG08622.1 - 7e-16 58.6 0.3 4.5e-15 56.0 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG08622.1 - 1.5e-07 31.0 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG08622.1 - 6.3e-07 30.2 0.1 8.2e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAG08622.1 - 0.056 13.0 0.6 0.24 10.9 0.4 2.1 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) p450 PF00067.22 OAG08623.1 - 6.5e-32 110.9 0.0 9.3e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cytomega_TRL10 PF06084.11 OAG08623.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Mito_carr PF00153.27 OAG08625.1 - 2.7e-21 75.3 3.9 2.8e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 OAG08626.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UbiA PF01040.18 OAG08627.1 - 0.0054 16.1 1.1 0.022 14.1 0.0 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF2718 PF10918.8 OAG08627.1 - 0.066 13.7 1.1 1.6 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) PQ-loop PF04193.14 OAG08628.1 - 2.2e-35 120.2 11.7 2.9e-19 68.6 3.0 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 OAG08628.1 - 0.63 10.1 5.3 7.4 6.7 0.1 3.3 2 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange TRAM_LAG1_CLN8 PF03798.16 OAG08629.1 - 1.9e-36 125.7 24.5 1.9e-36 125.7 24.5 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OAG08629.1 - 4.3e-22 77.5 0.1 4.3e-22 77.5 0.1 1.8 2 0 0 2 2 2 1 TRAM1-like protein RTA1 PF04479.13 OAG08630.1 - 1.2e-68 230.9 3.9 2e-68 230.1 3.9 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF3169 PF11368.8 OAG08630.1 - 0.0096 15.5 0.8 0.021 14.4 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) DUF4328 PF14219.6 OAG08630.1 - 0.02 14.5 0.4 0.02 14.5 0.4 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4328) Oleosin PF01277.17 OAG08630.1 - 0.29 10.9 7.1 16 5.3 0.0 3.8 4 0 0 4 4 4 0 Oleosin HemY_N PF07219.13 OAG08630.1 - 2.1 8.6 7.6 15 5.8 0.1 3.9 4 0 0 4 4 4 0 HemY protein N-terminus Fungal_trans_2 PF11951.8 OAG08631.1 - 1.2e-09 37.5 3.1 2.3e-09 36.6 3.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG08631.1 - 7.7e-08 32.3 12.2 1.2e-07 31.7 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 OAG08632.1 - 8e-22 77.5 0.6 1.5e-21 76.6 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG08632.1 - 2.5e-06 27.5 0.0 6.7e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like VPS38 PF17649.1 OAG08633.1 - 1.7e-15 56.9 0.0 5.6e-08 32.1 0.0 3.1 3 0 0 3 3 3 3 Vacuolar protein sorting 38 Atg14 PF10186.9 OAG08633.1 - 2.1e-14 53.3 0.0 3.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Mhr1 PF12829.7 OAG08634.1 - 3.5e-30 103.9 0.0 1e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination HTH_37 PF13744.6 OAG08634.1 - 0.017 15.1 1.0 0.091 12.7 0.5 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Synaptobrevin PF00957.21 OAG08634.1 - 0.21 11.4 3.2 0.49 10.2 3.2 1.6 1 0 0 1 1 1 0 Synaptobrevin Fungal_trans PF04082.18 OAG08635.1 - 1.3e-06 27.6 0.4 1.8e-06 27.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HNH_2 PF13391.6 OAG08636.1 - 1.8e-07 31.2 0.0 5.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease WzyE PF06899.11 OAG08636.1 - 0.075 12.0 3.2 0.12 11.2 3.2 1.4 1 0 0 1 1 1 0 WzyE protein, O-antigen assembly polymerase Spec3 PF15795.5 OAG08636.1 - 0.46 11.1 4.0 0.16 12.6 0.5 1.9 2 0 0 2 2 2 0 Ectodermal ciliogenesis protein DUF3632 PF12311.8 OAG08637.1 - 1e-11 45.6 0.0 1.4e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FAD_binding_3 PF01494.19 OAG08639.1 - 2e-08 33.9 0.0 2e-05 24.0 0.0 2.2 1 1 0 2 2 2 2 FAD binding domain Oxidored_q4 PF00507.19 OAG08640.1 - 0.01 16.0 4.0 0.21 11.8 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 MRF_C1 PF13887.6 OAG08640.1 - 0.18 11.0 0.0 0.41 9.8 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 EthD PF07110.11 OAG08641.1 - 1.4e-05 26.2 0.1 1.6e-05 25.9 0.1 1.1 1 0 0 1 1 1 1 EthD domain AMP-binding PF00501.28 OAG08642.1 - 1.7e-76 257.6 0.0 2.3e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAG08642.1 - 8.4e-62 209.3 0.1 3.6e-35 121.5 0.4 2.6 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 OAG08642.1 - 1.1e-19 70.6 0.0 5.8e-11 42.6 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG08642.1 - 0.0079 17.2 0.4 0.29 12.2 0.1 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.19 OAG08643.1 - 6.3e-23 81.6 0.8 1.9e-22 80.0 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain SE PF08491.10 OAG08643.1 - 0.00061 18.9 0.1 0.015 14.3 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 OAG08643.1 - 0.004 17.4 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 OAG08643.1 - 0.04 13.8 2.2 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 OAG08643.1 - 0.1 11.8 0.2 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG08643.1 - 0.15 11.3 0.9 0.2 10.9 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_12 PF13424.6 OAG08645.1 - 1.9e-35 121.0 1.6 3e-11 43.5 0.0 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG08645.1 - 2.7e-30 103.4 3.9 3.4e-11 42.6 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG08645.1 - 7.6e-07 28.7 0.4 0.0048 16.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG08645.1 - 2.6e-05 24.8 0.0 0.36 11.5 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG08645.1 - 0.00026 20.5 2.1 0.00094 18.6 2.1 1.7 1 1 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 OAG08645.1 - 0.00029 20.7 0.0 0.099 12.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG08645.1 - 0.00034 21.2 0.2 2.4 9.2 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG08645.1 - 0.00065 20.1 0.4 0.059 14.0 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG08645.1 - 0.00097 18.9 0.0 0.18 11.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG08645.1 - 0.016 15.7 0.0 1.1 9.8 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG08645.1 - 0.097 13.1 0.0 6.9 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG08645.1 - 0.1 13.3 0.1 8.3 7.3 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAG08647.1 - 1e-41 143.1 53.3 1.8e-41 142.2 50.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG08647.1 - 1.7e-17 63.1 15.1 2.7e-17 62.4 15.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG08647.1 - 1.8e-10 40.3 17.6 1.8e-10 40.3 17.6 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter DUF3671 PF12420.8 OAG08647.1 - 1.6 8.9 5.8 19 5.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function p450 PF00067.22 OAG08648.1 - 3.1e-41 141.6 0.0 4.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 P63C PF10546.9 OAG08648.1 - 0.096 13.3 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 P63C domain Fungal_trans PF04082.18 OAG08649.1 - 1.3e-11 44.1 0.0 2.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAG08650.1 - 3.5e-29 102.1 0.0 1.2e-28 100.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG08650.1 - 1.9e-06 27.7 1.2 0.00013 21.7 0.6 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG08650.1 - 5.6e-06 26.5 0.2 1.2e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG08650.1 - 0.00015 21.0 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG08650.1 - 0.00024 20.4 0.0 0.0022 17.3 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG08650.1 - 0.019 15.5 0.0 0.043 14.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG08650.1 - 0.044 12.8 0.0 0.47 9.4 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 OAG08650.1 - 0.055 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG08650.1 - 0.057 12.7 0.0 0.96 8.6 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG08650.1 - 0.15 10.7 0.0 0.92 8.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_10 PF13460.6 OAG08651.1 - 2.5e-35 122.0 0.0 2.8e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG08651.1 - 1.1e-07 31.6 0.0 2.5e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG08651.1 - 5.9e-07 29.3 0.1 3e-06 27.0 0.1 2.1 2 1 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 OAG08651.1 - 2.2e-05 24.7 0.1 4.7e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OAG08651.1 - 0.00065 20.0 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 OAG08651.1 - 0.0028 17.3 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.20 OAG08651.1 - 0.0038 17.4 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 OAG08651.1 - 0.0064 15.6 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG08651.1 - 0.019 14.1 0.0 0.47 9.6 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Glyco_trans_4_4 PF13579.6 OAG08651.1 - 0.047 14.1 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Shikimate_DH PF01488.20 OAG08651.1 - 0.097 12.7 0.5 0.32 11.0 0.5 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 OAG08651.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 OAG08651.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG08651.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1772 PF08592.11 OAG08652.1 - 0.087 13.1 5.0 0.17 12.2 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) MCD_N PF17408.2 OAG08653.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain Transferase PF02458.15 OAG08654.1 - 4.7e-08 32.1 0.0 1.5e-07 30.5 0.0 1.7 2 1 0 2 2 2 1 Transferase family Iron_permease PF04120.12 OAG08655.1 - 2.1e-33 114.9 12.9 7.7e-16 58.0 0.0 4.3 3 1 1 4 4 4 4 Low affinity iron permease Zot PF05707.12 OAG08656.1 - 0.00055 19.6 0.0 0.002 17.8 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.17 OAG08656.1 - 0.0047 17.1 0.1 0.043 13.9 0.1 2.2 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 OAG08656.1 - 0.017 15.4 0.0 5.5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 OAG08656.1 - 0.032 12.8 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Zn_clus PF00172.18 OAG08657.1 - 6.2e-07 29.4 6.7 1e-06 28.7 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNB PF00773.19 OAG08658.1 - 0.13 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 RNB domain Fungal_trans PF04082.18 OAG08659.1 - 6e-14 51.7 0.1 1e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG08659.1 - 8.6e-06 25.8 11.3 1.7e-05 24.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 OAG08660.1 - 4.8e-90 302.1 0.0 5.5e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Glyco_hydro_43 PF04616.14 OAG08662.1 - 1.5e-45 155.7 5.6 2e-45 155.3 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 OAG08662.1 - 1.4e-40 138.5 1.3 2.9e-40 137.4 1.3 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 OAG08662.1 - 8e-11 42.1 0.3 2e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 OAG08662.1 - 0.0065 16.1 2.2 0.0065 16.1 2.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Beta_elim_lyase PF01212.21 OAG08664.1 - 7.2e-63 212.6 0.0 9.4e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OAG08664.1 - 0.0048 15.5 0.0 0.0082 14.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG08664.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II OKR_DC_1 PF01276.20 OAG08664.1 - 0.081 11.6 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 OAG08664.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NIPSNAP PF07978.13 OAG08666.1 - 0.079 13.2 0.7 0.19 11.9 0.1 2.0 2 0 0 2 2 2 0 NIPSNAP Peptidase_S41 PF03572.18 OAG08667.1 - 5.6e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Bacteriocin_IIi PF11758.8 OAG08667.1 - 0.45 10.4 5.4 1.2 9.0 3.1 2.3 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin ADH_N_2 PF16884.5 OAG08668.1 - 2.1e-31 108.0 0.0 4.8e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAG08668.1 - 5.3e-21 75.0 0.0 9.8e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG08668.1 - 2.9e-11 44.6 0.2 5.7e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Cullin_binding PF03556.15 OAG08669.1 - 0.0033 17.8 0.3 0.0073 16.8 0.3 1.7 1 0 0 1 1 1 1 Cullin binding HET PF06985.11 OAG08669.1 - 0.016 15.5 0.2 0.058 13.7 0.0 2.1 3 0 0 3 3 3 0 Heterokaryon incompatibility protein (HET) dCMP_cyt_deam_1 PF00383.23 OAG08670.1 - 4.6e-10 39.3 0.1 6.2e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OAG08670.1 - 0.00019 21.6 0.4 0.0084 16.3 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OAG08670.1 - 0.0053 16.4 0.9 0.24 11.0 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases adh_short_C2 PF13561.6 OAG08671.1 - 8.3e-24 84.4 0.1 3.5e-23 82.4 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG08671.1 - 1.9e-11 43.8 0.0 5.2e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase PRKCSH PF07915.13 OAG08672.1 - 3.8e-19 69.5 0.1 1.4e-18 67.7 0.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 OAG08672.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Pkinase PF00069.25 OAG08673.1 - 3.1e-67 226.7 0.0 5.9e-67 225.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08673.1 - 1.4e-34 119.6 0.0 2.3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAG08673.1 - 1.2e-08 35.2 1.2 7.1e-07 29.5 0.1 2.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 OAG08673.1 - 0.011 16.0 0.2 0.061 13.6 0.0 2.3 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 OAG08673.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG08673.1 - 0.037 14.0 0.1 0.64 9.9 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG08673.1 - 0.062 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OAG08673.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HSCB_C PF07743.13 OAG08674.1 - 1.2e-21 77.0 6.8 3.9e-21 75.3 5.3 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OAG08674.1 - 6e-06 26.3 0.2 1.2e-05 25.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain ThiD2 PF17792.1 OAG08674.1 - 0.0029 18.1 0.8 0.0055 17.2 0.4 1.7 2 0 0 2 2 2 1 ThiD2 family Actino_peptide PF14408.6 OAG08674.1 - 3.1 8.0 6.0 5.5 7.2 6.0 1.3 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes Glyco_hydro_61 PF03443.14 OAG08675.1 - 1.3e-50 172.2 0.4 1.5e-50 172.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Adeno_E4_34 PF04528.13 OAG08676.1 - 0.29 11.0 1.7 0.37 10.6 1.6 1.3 1 1 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Abhydrolase_6 PF12697.7 OAG08677.1 - 1.1e-13 52.3 0.0 1.3e-13 52.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG08677.1 - 0.00033 20.0 0.0 0.74 9.0 0.0 2.3 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DUF900 PF05990.12 OAG08677.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) COesterase PF00135.28 OAG08678.1 - 6.9e-99 332.0 0.0 8.5e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG08678.1 - 2.6e-05 24.2 0.1 0.00014 21.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG08678.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SLAC1 PF03595.17 OAG08679.1 - 6e-80 268.9 40.3 6.8e-80 268.7 40.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1996 PF09362.10 OAG08680.1 - 2.3e-73 247.0 3.9 3.1e-73 246.6 3.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PX PF00787.24 OAG08683.1 - 1.1e-17 64.0 0.0 1.4e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 PX domain SAS4 PF15460.6 OAG08684.1 - 5.4e-10 39.3 5.3 5.4e-10 39.3 5.3 2.1 1 1 1 2 2 2 1 Something about silencing, SAS, complex subunit 4 DUF2767 PF10965.8 OAG08684.1 - 0.059 13.4 0.2 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) DUF3072 PF11272.8 OAG08684.1 - 1.7 8.6 6.6 0.46 10.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Rib_hydrolayse PF02267.17 OAG08685.1 - 0.0037 16.7 0.0 0.069 12.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosyl cyclase Lebercilin PF15619.6 OAG08686.1 - 0.00017 21.3 0.5 0.00017 21.3 0.5 3.2 1 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Nup54 PF13874.6 OAG08686.1 - 0.00029 21.0 4.8 0.00029 21.0 4.8 2.7 1 1 0 2 2 2 1 Nucleoporin complex subunit 54 FAM76 PF16046.5 OAG08686.1 - 0.0013 18.2 0.6 0.0013 18.2 0.6 2.2 1 1 1 2 2 2 1 FAM76 protein FPP PF05911.11 OAG08686.1 - 0.018 13.2 19.1 0.0047 15.2 15.5 1.7 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Phage_rep_O PF04492.13 OAG08686.1 - 0.099 13.2 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage replication protein O CALCOCO1 PF07888.11 OAG08686.1 - 0.15 10.9 18.0 0.26 10.1 18.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.8 OAG08686.1 - 0.34 10.9 24.4 0.049 13.6 9.8 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding CHD5 PF04420.14 OAG08686.1 - 0.42 10.4 0.0 0.42 10.4 0.0 2.8 3 0 0 3 3 3 0 CHD5-like protein STAT_alpha PF01017.20 OAG08686.1 - 0.48 10.3 0.1 0.48 10.3 0.1 2.8 2 1 0 2 2 2 0 STAT protein, all-alpha domain Fez1 PF06818.15 OAG08686.1 - 0.53 10.7 20.8 1.7 9.1 12.6 2.4 1 1 1 2 2 2 0 Fez1 GldM_N PF12081.8 OAG08686.1 - 1.6 8.8 15.1 3.2 7.8 15.1 1.4 1 0 0 1 1 1 0 GldM N-terminal domain Jnk-SapK_ap_N PF09744.9 OAG08686.1 - 2.6 8.2 26.4 0.64 10.2 7.0 2.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 AAA_13 PF13166.6 OAG08686.1 - 5 5.6 20.1 1.3 7.6 16.8 1.7 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 OAG08686.1 - 8.9 5.6 26.2 0.44 9.9 8.4 2.6 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 OAG08686.1 - 9 6.3 18.4 0.064 13.3 6.6 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4472 PF14739.6 OAG08686.1 - 9.6 7.0 17.9 14 6.4 1.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) FAD_binding_3 PF01494.19 OAG08688.1 - 3.6e-27 95.5 0.0 4.7e-13 49.1 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAG08688.1 - 0.00024 20.3 1.3 0.013 14.5 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG08688.1 - 0.0004 19.7 0.0 0.0022 17.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG08688.1 - 0.0023 17.6 0.1 0.56 9.7 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 OAG08688.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase K_oxygenase PF13434.6 OAG08688.1 - 0.1 11.7 0.1 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG08688.1 - 0.18 11.0 0.4 0.31 10.2 0.1 1.5 2 0 0 2 2 2 0 Thi4 family ChaC PF04752.12 OAG08689.1 - 4.5e-57 193.0 0.0 5.7e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein DNA_mis_repair PF01119.19 OAG08690.1 - 1.3e-11 44.2 0.0 2.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG08690.1 - 3e-08 33.6 0.0 6.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG08690.1 - 4.4e-07 30.4 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ada_Zn_binding PF02805.16 OAG08691.1 - 6.8e-27 93.3 7.9 1e-26 92.7 7.9 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 OAG08691.1 - 2e-08 34.1 0.0 4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 OAG08691.1 - 3.2e-05 24.1 0.0 6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 OAG08691.1 - 0.0015 18.8 0.1 0.0066 16.8 0.1 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain Zip PF02535.22 OAG08692.1 - 2.2e-47 161.9 4.3 1.4e-46 159.3 4.3 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_16 PF00722.21 OAG08694.1 - 4.2e-07 29.6 0.0 2.5e-06 27.1 0.0 2.2 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 Delta_lysin PF05372.11 OAG08694.1 - 0.11 11.8 0.8 0.28 10.5 0.8 1.7 1 0 0 1 1 1 0 Delta lysin family GTP_EFTU PF00009.27 OAG08696.1 - 1.1e-45 155.5 0.0 1.8e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OAG08696.1 - 1.7e-35 122.2 7.0 3.8e-35 121.1 7.0 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 OAG08696.1 - 2.6e-21 75.6 0.0 8.2e-21 74.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAG08696.1 - 1.5e-19 69.8 0.0 1.6e-18 66.5 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG08696.1 - 2.3e-07 31.1 0.1 5.7e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAG08696.1 - 5.8e-07 29.5 0.0 1.9e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OAG08696.1 - 0.00022 21.3 0.2 0.00051 20.1 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG08696.1 - 0.098 12.1 0.1 0.65 9.4 0.1 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF5505 PF17610.2 OAG08696.1 - 0.16 12.0 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Sortase PF04203.13 OAG08696.1 - 0.17 11.7 0.1 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Sortase domain Thiolase_N PF00108.23 OAG08697.1 - 1.8e-93 312.7 0.3 3.4e-93 311.7 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG08697.1 - 4.2e-44 149.1 2.6 1.3e-42 144.4 1.7 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG08697.1 - 5e-06 26.3 5.1 0.00014 21.6 1.5 3.0 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAG08697.1 - 0.0035 17.1 4.4 0.031 14.1 0.1 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 OAG08697.1 - 0.0048 15.6 0.7 0.0084 14.9 0.2 1.6 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 OAG08697.1 - 0.019 15.0 1.0 18 5.4 0.0 3.6 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain HET PF06985.11 OAG08698.1 - 4.5e-31 108.2 0.1 1.1e-30 106.9 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1294 PF06961.13 OAG08701.1 - 3.2e-25 88.1 0.2 3.2e-25 88.1 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) TauE PF01925.19 OAG08701.1 - 0.0031 17.2 4.0 0.0039 16.9 4.0 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Pkinase PF00069.25 OAG08703.1 - 3.2e-69 233.2 0.0 4.4e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08703.1 - 1.6e-37 129.2 0.0 2.6e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG08703.1 - 1.8e-06 27.5 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG08703.1 - 0.0061 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_27 PF17935.1 OAG08703.1 - 0.01 15.9 0.1 0.041 14.0 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YrbL-PhoP_reg PF10707.9 OAG08703.1 - 0.014 14.9 0.6 0.057 12.9 0.0 2.3 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Bromodomain PF00439.25 OAG08704.1 - 3.6e-31 107.1 0.1 2.8e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 Bromodomain FRD2 PF03197.13 OAG08704.1 - 0.18 12.1 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Rad17 PF03215.15 OAG08706.1 - 5.4e-31 108.0 0.0 1e-30 107.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 OAG08706.1 - 7.6e-05 23.2 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG08706.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG08706.1 - 0.0038 17.5 0.0 0.0091 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAG08706.1 - 0.012 15.4 0.0 0.077 12.7 0.0 2.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 OAG08706.1 - 0.013 15.3 0.2 0.033 13.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAG08706.1 - 0.015 15.8 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAG08706.1 - 0.031 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 OAG08706.1 - 0.05 13.6 0.1 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 OAG08706.1 - 0.12 11.7 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 OAG08706.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 OAG08706.1 - 0.25 11.2 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_19 PF13245.6 OAG08706.1 - 0.3 11.4 1.2 0.51 10.7 0.2 1.9 2 1 0 2 2 2 0 AAA domain TFIIF_beta PF02270.15 OAG08707.1 - 3.7e-22 78.2 0.0 7.7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 OAG08707.1 - 1.1e-15 58.5 0.9 1.1e-14 55.3 0.9 2.3 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 OAG08707.1 - 7.9e-07 30.0 2.1 1.7e-06 28.9 2.1 1.7 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PCI PF01399.27 OAG08708.1 - 7.2e-12 45.7 0.0 2.4e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 OAG08708.1 - 0.00017 21.4 0.2 0.00036 20.3 0.2 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 SNAP PF14938.6 OAG08708.1 - 0.0029 17.1 0.7 0.0055 16.2 0.7 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 OAG08708.1 - 0.0069 16.9 0.6 8.4 7.0 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat Laminin_II PF06009.12 OAG08708.1 - 0.066 13.2 1.3 1.3 9.0 0.1 2.7 3 0 0 3 3 3 0 Laminin Domain II Ribosomal_L21p PF00829.21 OAG08709.1 - 1.1e-09 38.4 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Mito_fiss_reg PF05308.11 OAG08709.1 - 1.4 9.0 5.3 2 8.5 3.5 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Ribosomal_S8e PF01201.22 OAG08710.1 - 1.1e-46 158.4 3.4 2.4e-46 157.3 3.4 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3464 PF11947.8 OAG08710.1 - 3.3 7.5 7.2 6.9 6.4 7.2 1.6 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 AATase PF07247.12 OAG08712.1 - 0.022 13.3 0.0 0.036 12.6 0.0 1.4 1 1 0 1 1 1 0 Alcohol acetyltransferase Mt_ATP-synt_B PF05405.14 OAG08713.1 - 8.8e-49 165.3 5.4 1.1e-48 165.0 5.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Virul_Fac PF10139.9 OAG08713.1 - 0.011 14.1 1.4 0.013 13.8 1.4 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor SapB_1 PF05184.15 OAG08713.1 - 0.28 11.2 0.6 0.64 10.1 0.6 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 1 NPV_P10 PF05531.12 OAG08713.1 - 1.9 9.0 5.9 1 9.9 0.7 2.7 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CBF PF03914.17 OAG08714.1 - 3.7e-38 131.2 1.4 2e-37 128.9 0.1 2.7 3 0 0 3 3 3 1 CBF/Mak21 family zf-CCCH_3 PF15663.5 OAG08715.1 - 0.00011 22.4 1.5 0.00011 22.4 1.5 3.0 1 1 1 3 3 3 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 OAG08715.1 - 0.023 14.5 0.1 0.023 14.5 0.1 4.5 5 0 0 5 5 5 0 CCCH-type zinc finger zf-CCCH PF00642.24 OAG08715.1 - 0.033 14.1 27.0 0.22 11.5 1.1 5.2 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG08715.1 - 0.26 11.4 24.2 0.28 11.3 0.2 5.3 5 1 0 5 5 5 0 Zinc finger domain Sel1 PF08238.12 OAG08716.1 - 2.1e-15 56.8 2.5 0.00011 22.7 0.1 4.2 4 0 0 4 4 4 3 Sel1 repeat bZIP_1 PF00170.21 OAG08717.1 - 9e-09 35.3 10.6 9e-09 35.3 10.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 OAG08717.1 - 8.8e-07 29.4 10.1 8.8e-07 29.4 10.1 2.2 2 1 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG08717.1 - 1.3e-06 28.4 6.7 3.6e-06 27.0 6.7 1.8 1 0 0 1 1 1 1 Basic region leucine zipper TLE_N PF03920.15 OAG08717.1 - 0.011 15.8 1.3 0.023 14.8 1.3 1.5 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain UPF0242 PF06785.11 OAG08717.1 - 0.51 10.4 10.5 0.99 9.5 10.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 OAG08718.1 - 2.2e-33 113.7 17.8 1.2e-09 38.6 0.1 7.4 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG08718.1 - 4.8e-15 55.6 0.0 0.04 14.2 0.0 4.6 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 OAG08718.1 - 6e-13 48.1 1.8 9.7e-13 47.4 0.4 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 OAG08718.1 - 5.2e-06 26.0 0.0 0.034 13.5 0.0 4.0 4 1 0 4 4 4 2 WD40-like domain eIF2A PF08662.11 OAG08718.1 - 5.5e-06 26.4 0.0 0.66 9.8 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A SpoIIE PF07228.12 OAG08719.1 - 7.6e-07 29.2 0.3 3e-06 27.3 0.3 2.0 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OAG08719.1 - 1.7e-06 27.8 0.0 0.0026 17.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OAG08719.1 - 3.7e-06 26.7 0.7 8.4e-06 25.6 0.7 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Dynamin_N PF00350.23 OAG08720.1 - 1e-31 110.3 0.1 2.1e-31 109.2 0.1 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAG08720.1 - 7.1e-26 91.1 0.1 1.8e-25 89.8 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 OAG08720.1 - 0.00012 22.1 0.1 0.0011 19.0 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 OAG08720.1 - 0.0022 17.8 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain GED PF02212.18 OAG08720.1 - 0.006 16.7 0.4 0.039 14.1 0.0 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain AAA_21 PF13304.6 OAG08720.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AviRa PF11599.8 OAG08720.1 - 0.021 14.3 0.1 0.057 12.9 0.1 1.7 1 0 0 1 1 1 0 RRNA methyltransferase AviRa AAA_29 PF13555.6 OAG08720.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG08720.1 - 0.042 14.3 0.2 0.17 12.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 OAG08720.1 - 0.047 13.2 0.0 5.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B APOC4 PF15119.6 OAG08720.1 - 0.059 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein C4 ABC_tran PF00005.27 OAG08720.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF1678 PF07913.11 OAG08720.1 - 0.11 12.2 0.2 2 8.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1678) RTC4 PF14474.6 OAG08720.1 - 0.12 12.5 0.2 0.55 10.4 0.1 2.1 2 0 0 2 2 2 0 RTC4-like domain SOG2 PF10428.9 OAG08722.1 - 6.2 5.9 5.9 8.3 5.5 5.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Sulfotransfer_3 PF13469.6 OAG08723.1 - 0.0048 17.3 0.0 0.0068 16.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF2201_N PF13203.6 OAG08723.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain HlyE PF06109.13 OAG08724.1 - 0.41 9.9 1.9 0.63 9.3 1.9 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) MFS_1 PF07690.16 OAG08725.1 - 3.9e-32 111.5 33.6 3.9e-32 111.5 33.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG08725.1 - 1.2e-10 40.9 11.9 1.2e-10 40.9 11.9 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.18 OAG08726.1 - 4e-05 23.7 7.8 6.5e-05 23.0 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC-167 PF15188.6 OAG08726.1 - 1.2 9.6 5.1 1 9.7 1.8 2.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 ABM PF03992.16 OAG08727.1 - 8.2e-14 51.5 0.0 9.7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Asp PF00026.23 OAG08728.1 - 6.1e-53 180.3 0.0 7.6e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG08728.1 - 7.8e-10 39.3 0.0 3.7e-05 24.0 0.2 3.3 2 1 1 3 3 3 3 Xylanase inhibitor N-terminal 2OG-FeII_Oxy_2 PF13532.6 OAG08729.1 - 1.7e-28 100.1 0.0 2.4e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPATA6 PF14909.6 OAG08729.1 - 0.063 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Fungal_trans PF04082.18 OAG08731.1 - 1.1e-15 57.4 0.0 2.2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG08731.1 - 6.7e-07 29.3 11.3 1.1e-06 28.7 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 OAG08731.1 - 0.064 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Sacchrp_dh_C PF16653.5 OAG08733.1 - 4.1e-10 40.2 0.0 4.5e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain GH131_N PF18271.1 OAG08734.1 - 7.2e-78 261.8 0.1 8.4e-78 261.6 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CHASE2 PF05226.11 OAG08734.1 - 0.059 13.1 0.1 0.072 12.8 0.1 1.4 1 1 0 1 1 1 0 CHASE2 domain PAF-AH_p_II PF03403.13 OAG08736.1 - 8.9e-35 119.9 0.0 2.6e-34 118.4 0.0 1.6 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAG08736.1 - 0.014 14.6 0.5 0.97 8.7 0.0 2.6 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG08736.1 - 0.023 15.3 0.0 0.05 14.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OAG08736.1 - 0.13 11.2 0.0 1 8.2 0.0 2.1 1 1 0 1 1 1 0 Chlorophyllase enzyme Dioxygenase_C PF00775.21 OAG08737.1 - 2.7e-40 137.7 0.0 4e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG08737.1 - 3.2e-26 91.0 0.1 5.9e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SpaA PF17802.1 OAG08737.1 - 0.00054 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 OAG08737.1 - 0.033 14.4 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain ADH_zinc_N PF00107.26 OAG08738.1 - 2.6e-06 27.4 0.1 5.9e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG08738.1 - 0.0071 15.7 1.2 0.013 14.8 0.6 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 OAG08738.1 - 0.016 15.6 0.3 0.036 14.5 0.1 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TP_methylase PF00590.20 OAG08738.1 - 0.091 12.7 0.2 0.17 11.8 0.1 1.4 1 1 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases GFA PF04828.14 OAG08739.1 - 3.5e-06 27.3 0.7 3.5e-06 27.3 0.7 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Pmp3 PF01679.17 OAG08740.1 - 9.3e-24 83.4 7.3 1.1e-23 83.2 7.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PhoD PF09423.10 OAG08742.1 - 3.2e-08 33.0 0.6 4.4e-07 29.2 0.6 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase PEHE PF15275.6 OAG08742.1 - 0.0028 18.3 1.0 0.0028 18.3 1.0 4.1 3 0 0 3 3 3 1 PEHE domain GCS2 PF04107.13 OAG08742.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) DUF3439 PF11921.8 OAG08742.1 - 0.41 10.6 5.0 1 9.3 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S8 PF00082.22 OAG08743.1 - 1.2e-36 126.5 1.3 1.2e-36 126.5 1.3 1.9 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 OAG08743.1 - 1.4e-27 95.5 0.2 2.8e-27 94.6 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OAG08743.1 - 0.047 14.5 0.4 0.13 13.0 0.4 1.9 1 1 0 1 1 1 0 Peptidase S8 pro-domain RTC_insert PF05189.13 OAG08744.1 - 5e-32 110.5 0.0 9.8e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 OAG08744.1 - 3.3e-29 101.7 0.1 4.1e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC4 PF14474.6 OAG08745.1 - 4.7e-27 94.5 0.0 8.3e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain IBR PF01485.21 OAG08746.1 - 3.6e-12 46.3 36.8 1.1e-07 31.9 6.3 3.7 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain Aldo_ket_red PF00248.21 OAG08748.1 - 1.9e-67 227.6 0.0 2.3e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family bZIP_1 PF00170.21 OAG08749.1 - 4.6e-06 26.6 8.9 7.6e-06 25.9 8.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 OAG08749.1 - 0.17 11.6 2.5 5.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 bZIP_2 PF07716.15 OAG08749.1 - 0.85 9.8 7.8 0.079 13.0 3.2 1.7 2 0 0 2 2 2 0 Basic region leucine zipper SH3BGR PF04908.15 OAG08750.1 - 0.00064 19.8 1.5 0.0012 18.9 0.0 2.2 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein PPP4R2 PF09184.11 OAG08750.1 - 0.0011 18.6 13.6 0.0016 18.1 13.6 1.3 1 0 0 1 1 1 1 PPP4R2 NOA36 PF06524.12 OAG08750.1 - 0.053 12.8 17.3 0.08 12.3 17.3 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 OAG08750.1 - 0.23 10.9 24.8 0.44 9.9 24.8 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAG08750.1 - 0.23 9.7 19.9 0.33 9.2 19.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 OAG08750.1 - 0.25 10.7 14.4 0.43 10.0 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 OAG08750.1 - 0.3 9.3 24.3 0.45 8.7 24.3 1.2 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.11 OAG08750.1 - 0.43 10.2 22.1 0.75 9.4 22.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 OAG08750.1 - 0.59 10.2 18.6 1.2 9.2 18.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Nucleo_P87 PF07267.11 OAG08750.1 - 0.64 8.8 13.5 0.87 8.4 13.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mpp10 PF04006.12 OAG08750.1 - 0.82 8.0 24.7 1.1 7.7 24.7 1.1 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 OAG08750.1 - 0.94 7.5 29.3 1.3 7.0 29.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Merozoite_SPAM PF07133.11 OAG08750.1 - 0.97 9.4 31.0 1.8 8.5 31.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF3449 PF11931.8 OAG08750.1 - 0.97 9.2 10.3 1.6 8.5 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) RXT2_N PF08595.11 OAG08750.1 - 1.4 8.9 11.3 2.6 8.0 11.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 OAG08750.1 - 1.5 8.7 18.6 2.5 7.9 18.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region SAPS PF04499.15 OAG08750.1 - 1.7 7.3 9.0 2.1 7.1 9.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFB6 PF17110.5 OAG08750.1 - 2.7 7.7 9.4 4.4 7.0 9.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4820 PF16091.5 OAG08750.1 - 3.5 6.9 7.6 5.6 6.3 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Vfa1 PF08432.10 OAG08750.1 - 4 7.7 15.3 10 6.4 15.3 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TLP-20 PF06088.11 OAG08750.1 - 7.5 6.4 9.5 15 5.5 9.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SNF2_N PF00176.23 OAG08751.1 - 1.6e-54 185.0 0.5 2.4e-54 184.4 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG08751.1 - 1.6e-18 67.0 0.0 6.8e-17 61.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG08751.1 - 4.5e-11 43.0 0.0 1e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG08751.1 - 0.00019 20.7 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase VMA21 PF09446.10 OAG08752.1 - 7.5e-13 48.4 13.5 1.1e-12 47.8 13.5 1.3 1 0 0 1 1 1 1 VMA21-like domain DUF765 PF05570.11 OAG08752.1 - 0.79 9.9 3.6 1.4 9.2 3.6 1.4 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) DUF2406 PF10295.9 OAG08753.1 - 1.2e-24 86.7 0.1 3.2e-24 85.4 0.1 1.8 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aldedh PF00171.22 OAG08754.1 - 1.4e-137 459.0 0.2 1.7e-137 458.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.18 OAG08755.1 - 5e-174 578.4 20.3 6.8e-174 578.0 20.3 1.2 1 0 0 1 1 1 1 Calreticulin family EspB PF05802.11 OAG08755.1 - 0.018 15.1 5.5 0.018 15.1 5.5 2.1 3 0 0 3 3 3 0 Enterobacterial EspB protein DUF1911 PF08929.10 OAG08755.1 - 0.042 14.6 0.1 0.12 13.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Cytadhesin_P30 PF07271.11 OAG08755.1 - 0.14 11.7 0.3 0.2 11.2 0.3 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF1752 PF08550.10 OAG08756.1 - 1.9e-08 34.0 2.4 3.7e-08 33.1 2.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.16 OAG08758.1 - 7.8e-49 166.5 55.0 3.5e-47 161.0 56.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG08758.1 - 8.4e-23 80.6 12.4 1.8e-22 79.5 12.4 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG08758.1 - 1.5e-16 60.3 5.6 1.5e-16 60.3 5.6 3.9 3 2 0 4 4 4 2 Sugar (and other) transporter EOS1 PF12326.8 OAG08758.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 N-glycosylation protein Neurensin PF14927.6 OAG08758.1 - 2.1 8.0 7.9 14 5.4 0.0 4.1 3 1 0 3 3 3 0 Neurensin NDUFB10 PF10249.9 OAG08760.1 - 0.0039 17.7 0.0 0.004 17.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 OAG08760.1 - 0.025 15.3 0.0 0.038 14.7 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase BRO1 PF03097.18 OAG08761.1 - 3.5e-12 45.8 0.0 5.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain AA_permease_2 PF13520.6 OAG08762.1 - 2.6e-61 207.7 43.8 3.3e-61 207.4 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG08762.1 - 4.8e-18 65.0 32.4 6.5e-18 64.6 32.4 1.2 1 0 0 1 1 1 1 Amino acid permease HET PF06985.11 OAG08763.1 - 1.4e-30 106.6 0.0 3e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 OAG08764.1 - 2.3e-73 247.2 0.0 2.9e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG08764.1 - 5.6e-12 46.5 0.0 1.3e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CorA PF01544.18 OAG08765.1 - 2.1e-07 30.6 4.5 4.7e-07 29.4 4.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PPV_E2_N PF00508.17 OAG08765.1 - 0.21 10.9 1.6 0.48 9.7 0.1 2.1 2 0 0 2 2 2 0 E2 (early) protein, N terminal WD40 PF00400.32 OAG08766.1 - 8.8e-11 42.2 0.1 1.6e-08 35.1 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG08766.1 - 0.036 14.3 0.0 0.085 13.2 0.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG08766.1 - 0.093 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAG08766.1 - 0.18 11.8 0.0 20 5.2 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 OAG08769.1 - 0.0068 16.1 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Phosphodiest PF01663.22 OAG08770.1 - 1.6e-88 297.8 0.8 2.2e-88 297.3 0.8 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG08770.1 - 2.4e-05 23.9 0.0 0.0037 16.7 0.0 2.2 2 0 0 2 2 2 2 Sulfatase DUF5353 PF17304.2 OAG08770.1 - 0.082 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5353) eIF-3_zeta PF05091.12 OAG08772.1 - 4.1e-204 679.4 0.0 4.8e-204 679.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HET PF06985.11 OAG08773.1 - 2.3e-33 115.6 0.8 3.5e-33 115.0 0.8 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FEZ PF07763.13 OAG08773.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein Bys1 PF04681.12 OAG08774.1 - 1.9e-07 31.2 2.2 2.1e-07 31.0 2.2 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein SIR2 PF02146.17 OAG08775.1 - 9.4e-42 142.9 0.0 1.8e-41 142.0 0.0 1.4 1 1 0 1 1 1 1 Sir2 family DUF1936 PF09151.10 OAG08775.1 - 0.0077 16.1 3.0 0.34 10.9 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1936) Fungal_trans_2 PF11951.8 OAG08776.1 - 4.9e-54 183.6 0.0 5.6e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG08776.1 - 1.6e-06 28.2 11.3 3.3e-06 27.1 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 OAG08777.1 - 2.4e-45 155.1 34.4 4.4e-37 127.9 16.8 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 OAG08777.1 - 1.3e-18 66.9 26.3 1.8e-13 50.0 16.1 2.1 2 0 0 2 2 2 2 Amino acid permease DUF1129 PF06570.11 OAG08777.1 - 0.46 9.9 5.9 1.8 8.0 5.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PhyH PF05721.13 OAG08778.1 - 7.6e-24 85.1 0.1 1.1e-23 84.6 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) adh_short_C2 PF13561.6 OAG08779.1 - 1.9e-46 158.5 0.3 2.3e-46 158.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG08779.1 - 2.2e-39 135.0 0.9 3e-39 134.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG08779.1 - 2.5e-12 47.1 0.2 3.7e-12 46.5 0.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG08779.1 - 0.051 12.9 0.1 0.14 11.4 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG08779.1 - 0.083 12.3 0.1 10 5.5 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG08779.1 - 0.093 12.1 0.0 4.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) DarA_N PF18788.1 OAG08779.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Defence against restriction A N-terminal Cu_amine_oxid PF01179.20 OAG08780.1 - 4.2e-156 520.0 0.0 5.1e-156 519.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAG08780.1 - 0.0038 17.4 0.0 0.026 14.8 0.0 2.2 1 1 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAG08780.1 - 0.0055 17.1 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain 2OG-FeII_Oxy_3 PF13640.6 OAG08781.1 - 1e-07 32.7 0.0 2.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG08782.1 - 8.4e-35 120.3 21.5 8.4e-35 120.3 21.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0715 PF17094.5 OAG08782.1 - 4 8.0 6.8 0.3 11.7 0.4 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0715) ORC6 PF05460.13 OAG08783.1 - 0.011 15.0 8.7 0.013 14.8 8.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF5427 PF10310.9 OAG08783.1 - 3.1 6.6 15.3 3.8 6.4 15.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF908 PF06012.12 OAG08783.1 - 5.7 6.3 5.4 5.6 6.3 5.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Neur_chan_memb PF02932.16 OAG08783.1 - 6.6 6.7 5.2 8.2 6.4 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 OAG08783.1 - 9.5 6.0 12.5 12 5.6 12.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 F_actin_cap_B PF01115.17 OAG08784.1 - 7.5e-104 346.6 0.0 8.8e-104 346.3 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit RNase_PH_C PF03725.15 OAG08784.1 - 0.1 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Peptidase_M10 PF00413.24 OAG08785.1 - 3.5e-18 65.9 0.0 6.6e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 OAG08785.1 - 0.0033 17.9 0.1 0.0089 16.5 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 OAG08785.1 - 0.041 13.1 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 OAG08785.1 - 0.069 12.8 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M8 PF01457.16 OAG08785.1 - 0.077 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Leishmanolysin Peptidase_M54 PF07998.11 OAG08785.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Astacin PF01400.24 OAG08785.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Metallopep PF12044.8 OAG08785.1 - 0.19 10.3 0.1 0.28 9.7 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase family Imm27 PF15590.6 OAG08785.1 - 2 8.2 4.9 3.9 7.3 0.0 3.4 4 0 0 4 4 4 0 Immunity protein 27 adh_short_C2 PF13561.6 OAG08786.1 - 3.3e-22 79.2 0.1 4.3e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG08786.1 - 3.9e-18 65.6 0.1 4.8e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG08786.1 - 9e-07 29.0 0.1 1.2e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 KR domain ThiF PF00899.21 OAG08786.1 - 0.083 12.2 0.4 0.21 10.9 0.0 1.7 1 1 1 2 2 2 0 ThiF family Fungal_trans PF04082.18 OAG08787.1 - 1.1e-14 54.1 0.1 1.8e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DRMBL PF07522.14 OAG08788.1 - 1.7e-33 115.1 0.1 7e-33 113.1 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OAG08788.1 - 1.4e-06 27.9 0.0 3.8e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain 4HBT_3 PF13622.6 OAG08789.1 - 4.9e-47 161.3 0.1 5.7e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Holin_BhlA PF10960.8 OAG08790.1 - 0.048 13.6 0.0 0.084 12.8 0.0 1.4 1 1 0 1 1 1 0 BhlA holin family Erg28 PF03694.13 OAG08792.1 - 1.8e-20 73.4 0.1 2.1e-20 73.2 0.1 1.0 1 0 0 1 1 1 1 Erg28 like protein AP_endonuc_2 PF01261.24 OAG08794.1 - 2.9e-26 92.2 0.0 6e-26 91.2 0.0 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel PP2C_2 PF13672.6 OAG08795.1 - 4e-07 29.9 0.0 6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OAG08795.1 - 1.5e-05 25.0 0.0 3.8e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OAG08795.1 - 0.00013 21.7 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C CBS PF00571.28 OAG08796.1 - 8e-09 35.8 0.0 0.02 15.3 0.0 3.1 2 1 1 3 3 3 3 CBS domain PWI PF01480.17 OAG08797.1 - 6.5e-25 87.3 0.2 1.1e-24 86.5 0.2 1.4 1 0 0 1 1 1 1 PWI domain Shisa PF13908.6 OAG08797.1 - 1 9.5 3.0 1.6 8.9 3.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3446 PF11928.8 OAG08799.1 - 0.071 13.4 0.2 0.088 13.1 0.2 1.1 1 0 0 1 1 1 0 Early growth response N-terminal domain FAA_hydrolase PF01557.18 OAG08800.1 - 1.7e-53 181.5 0.0 2.1e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Dynactin_p22 PF07426.11 OAG08801.1 - 0.067 13.0 1.6 1.9 8.3 0.3 2.5 2 0 0 2 2 2 0 Dynactin subunit p22 DUF948 PF06103.11 OAG08801.1 - 0.11 12.8 2.4 0.12 12.6 0.5 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF465 PF04325.13 OAG08801.1 - 0.24 11.5 1.9 0.64 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Seryl_tRNA_N PF02403.22 OAG08801.1 - 0.73 10.1 6.7 10 6.4 0.2 3.0 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.8 OAG08801.1 - 0.99 9.7 10.7 0.48 10.7 0.9 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 OAG08801.1 - 1.7 8.9 16.8 0.31 11.2 0.6 2.8 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 FAM184 PF15665.5 OAG08801.1 - 8.4 6.1 17.8 0.19 11.5 11.1 1.6 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF1771 PF08590.10 OAG08802.1 - 2e-14 53.7 10.9 2e-14 53.7 10.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 OAG08802.1 - 1.1e-07 31.7 9.5 6.3e-05 22.9 2.1 3.0 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 OAG08802.1 - 3.2e-07 30.1 5.2 0.0025 17.7 0.7 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAG08802.1 - 4.2e-07 30.2 7.5 0.0019 18.6 1.1 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Smr PF01713.21 OAG08802.1 - 2.2e-06 27.9 0.0 5.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Smr domain zf-CCCH_4 PF18044.1 OAG08802.1 - 4.5e-06 26.3 8.9 0.00063 19.5 0.4 3.0 2 1 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 OAG08802.1 - 0.018 15.7 6.3 0.14 12.8 1.1 2.6 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 OAG08802.1 - 0.62 10.3 2.9 25 5.1 0.1 2.1 1 1 1 2 2 2 0 Zinc-finger containing family zf-C3H1 PF10650.9 OAG08802.1 - 4 7.3 6.6 2.3 8.0 0.0 2.9 3 0 0 3 3 3 0 Putative zinc-finger domain SNARE_assoc PF09335.11 OAG08803.1 - 1.4e-14 54.6 5.5 1.4e-14 54.6 5.5 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF3899 PF13038.6 OAG08803.1 - 0.025 15.0 0.6 0.12 12.8 0.6 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) ATP-synt_E PF05680.12 OAG08803.1 - 0.12 12.8 0.6 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 ATP synthase E chain Phage_holin_2_4 PF16082.5 OAG08803.1 - 0.19 11.5 2.3 0.18 11.5 0.2 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Ctr PF04145.15 OAG08804.1 - 9.8e-35 120.3 0.2 1.7e-34 119.6 0.2 1.4 1 1 0 1 1 1 1 Ctr copper transporter family Hypoth_Ymh PF09509.10 OAG08804.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) SpoIIIAH PF12685.7 OAG08804.1 - 0.087 12.6 0.3 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 SpoIIIAH-like protein 3-HAO PF06052.12 OAG08805.1 - 3.9e-64 214.9 0.0 5.1e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 OAG08805.1 - 2.8e-06 27.0 0.0 1.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 OAG08805.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG08805.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain DZR PF12773.7 OAG08805.1 - 0.002 18.1 7.0 0.0038 17.2 7.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon Cupin_4 PF08007.12 OAG08805.1 - 0.072 12.5 0.1 0.15 11.4 0.0 1.3 1 1 0 1 1 1 0 Cupin superfamily protein ORC3_N PF07034.11 OAG08806.1 - 1.8e-36 125.9 0.0 3.4e-35 121.7 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 OAG08806.1 - 7.5e-28 97.4 0.1 2.8e-16 59.8 0.0 2.7 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal DUF3073 PF11273.8 OAG08806.1 - 0.47 11.2 1.9 0.5 11.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) DUF4187 PF13821.6 OAG08807.1 - 2.2e-20 72.2 0.2 4.6e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 OAG08807.1 - 1.6e-12 47.1 0.1 3e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 G-patch domain Virulence_fact PF13769.6 OAG08807.1 - 0.002 18.3 4.2 0.002 18.3 4.2 2.0 2 0 0 2 2 2 1 Virulence factor G-patch_2 PF12656.7 OAG08807.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.1 3 1 0 3 3 3 0 G-patch domain DUF3712 PF12505.8 OAG08808.1 - 2.9e-31 108.3 3.1 2.9e-31 108.3 3.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF4330 PF14221.6 OAG08808.1 - 0.022 14.9 1.4 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) PA14 PF07691.12 OAG08808.1 - 0.046 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 PA14 domain DUF1279 PF06916.13 OAG08808.1 - 0.13 12.8 0.0 0.31 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) OATP PF03137.20 OAG08808.1 - 0.15 10.3 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family OPA3 PF07047.12 OAG08810.1 - 8e-42 142.0 15.1 1.9e-41 140.8 15.1 1.6 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) CDC45 PF02724.14 OAG08810.1 - 0.004 15.5 2.4 0.0052 15.1 2.4 1.1 1 0 0 1 1 1 1 CDC45-like protein DivIC PF04977.15 OAG08810.1 - 0.021 14.6 0.1 0.021 14.6 0.1 2.9 2 1 1 3 3 3 0 Septum formation initiator S_4TM PF18159.1 OAG08810.1 - 0.025 13.9 0.8 0.063 12.6 0.0 1.9 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain DUF3801 PF12687.7 OAG08810.1 - 0.032 14.3 6.7 0.043 13.9 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Peptidase_S49_N PF08496.10 OAG08810.1 - 0.076 13.1 0.1 0.076 13.1 0.1 2.5 1 1 2 3 3 3 0 Peptidase family S49 N-terminal DUF5320 PF17253.2 OAG08810.1 - 0.2 12.7 2.9 1.9 9.6 0.1 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DUF1178 PF06676.11 OAG08810.1 - 0.37 11.2 6.3 0.081 13.3 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) DUF1003 PF06210.11 OAG08810.1 - 0.43 10.7 0.0 0.43 10.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) Fez1 PF06818.15 OAG08810.1 - 4.4 7.7 12.6 6.9 7.1 12.3 1.5 1 1 0 1 1 1 0 Fez1 Cnn_1N PF07989.11 OAG08810.1 - 6 7.1 10.0 0.75 10.0 1.2 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Myosin_head PF00063.21 OAG08811.1 - 8.8e-242 804.1 6.3 1.1e-241 803.8 6.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 OAG08811.1 - 7e-62 209.2 0.0 1.2e-61 208.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Myosin_TH1 PF06017.13 OAG08811.1 - 6.5e-52 175.9 0.0 1.4e-51 174.8 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Pkinase_Tyr PF07714.17 OAG08811.1 - 5.6e-44 150.4 0.0 1.2e-43 149.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.28 OAG08811.1 - 9.3e-14 50.8 0.1 2.6e-13 49.3 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG08811.1 - 6.5e-12 45.1 0.0 1.7e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG08811.1 - 1.7e-09 37.2 0.0 4.7e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain POLO_box PF00659.18 OAG08811.1 - 9.4e-08 32.1 0.4 0.00023 21.3 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OAG08811.1 - 1.5e-05 24.5 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like AAA_22 PF13401.6 OAG08811.1 - 0.041 14.2 0.0 0.17 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Pkinase_fungal PF17667.1 OAG08811.1 - 0.087 11.6 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase IQ PF00612.27 OAG08811.1 - 0.1 12.5 10.2 1.9 8.5 1.3 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Kdo PF06293.14 OAG08811.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG08811.1 - 0.13 12.2 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Hpr_kinase_C PF07475.12 OAG08811.1 - 0.36 10.3 0.8 13 5.3 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain FTA2 PF13095.6 OAG08812.1 - 2.9e-26 92.5 0.0 4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_3_C PF01915.22 OAG08816.1 - 2e-63 214.1 0.0 5e-63 212.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG08816.1 - 8.8e-55 186.3 0.0 1.5e-54 185.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 OAG08816.1 - 3.4e-23 82.1 0.1 5.9e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 OAG08816.1 - 3.6e-20 71.8 0.1 8.8e-20 70.6 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Sin3a_C PF16879.5 OAG08817.1 - 9.1e-63 212.6 13.3 9.1e-63 212.6 13.3 3.9 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 OAG08817.1 - 6.3e-42 141.5 5.3 5.9e-17 61.5 0.9 4.2 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OAG08817.1 - 1.8e-39 133.7 1.0 7.4e-39 131.8 0.0 2.5 2 0 0 2 2 2 1 Sin3 family co-repressor AAA PF00004.29 OAG08818.1 - 6.2e-16 59.0 0.0 1.5e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAG08818.1 - 5.1e-14 52.4 0.0 1.2e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OAG08818.1 - 8.5e-13 48.5 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 OAG08818.1 - 5.2e-08 33.0 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OAG08818.1 - 1.1e-05 25.9 0.3 0.00015 22.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 OAG08818.1 - 1.3e-05 25.2 0.1 3.9e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG08818.1 - 1.5e-05 25.3 0.0 4.9e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAG08818.1 - 6.1e-05 22.5 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OAG08818.1 - 7.1e-05 22.6 0.1 0.00021 21.1 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 OAG08818.1 - 0.00078 19.7 0.3 0.0026 18.1 0.3 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 OAG08818.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAG08818.1 - 0.0015 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 OAG08818.1 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAG08818.1 - 0.0033 16.6 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 OAG08818.1 - 0.0044 16.8 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_7 PF12775.7 OAG08818.1 - 0.0046 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 OAG08818.1 - 0.0061 16.3 0.1 0.043 13.5 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG08818.1 - 0.0072 16.3 0.1 0.046 13.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAG08818.1 - 0.016 15.5 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAG08818.1 - 0.024 14.7 0.0 0.076 13.0 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_6 PF12774.7 OAG08818.1 - 0.066 12.2 0.0 0.74 8.7 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 OAG08818.1 - 0.071 13.1 0.0 0.48 10.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG08818.1 - 0.084 13.4 0.0 0.23 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 OAG08818.1 - 0.11 12.3 0.2 1.6 8.4 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase TniB PF05621.11 OAG08818.1 - 0.11 11.9 0.1 1.6 8.1 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein AAA_3 PF07726.11 OAG08818.1 - 0.15 11.9 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG08818.1 - 0.17 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zn_clus PF00172.18 OAG08821.1 - 1.1e-05 25.4 8.8 2.3e-05 24.4 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2770 PF10968.8 OAG08822.1 - 0.079 12.9 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) Thioredoxin_4 PF13462.6 OAG08823.1 - 7.8e-09 35.9 0.0 1.3e-08 35.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OAG08823.1 - 0.017 14.9 2.8 1.7 8.4 0.1 2.7 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Acyl-CoA_ox_N PF14749.6 OAG08823.1 - 0.019 15.5 0.2 0.15 12.6 0.2 2.0 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal DUF5393 PF17371.2 OAG08823.1 - 0.058 11.5 0.0 0.074 11.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5393) NPL4 PF05021.15 OAG08824.1 - 2.4e-139 463.9 0.0 3e-139 463.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 OAG08824.1 - 7.7e-68 227.2 0.0 1.3e-67 226.4 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 OAG08824.1 - 0.017 15.6 0.0 0.049 14.1 0.0 1.8 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 OAG08825.1 - 5.7e-80 267.1 1.1 6.6e-80 266.9 1.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 OAG08825.1 - 0.0018 18.3 0.1 0.0034 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) PEP-utilisers_N PF05524.13 OAG08825.1 - 0.05 13.8 1.0 0.081 13.1 1.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF3844 PF12955.7 OAG08826.1 - 2.9e-34 117.4 1.0 4.3e-34 116.8 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) DUF2740 PF10872.8 OAG08826.1 - 0.2 11.6 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Toxin_35 PF10530.9 OAG08826.1 - 4.3 7.4 7.9 8.1 6.5 7.9 1.3 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold MCM3AP_GANP PF16769.5 OAG08827.1 - 0.059 11.6 0.2 0.08 11.2 0.2 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP DIL PF01843.19 OAG08828.1 - 0.079 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 DIL domain Myelin_PLP PF01275.19 OAG08828.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) PTR2 PF00854.21 OAG08829.1 - 6.7e-94 314.9 10.4 1.1e-93 314.3 10.4 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG08829.1 - 0.001 18.1 27.3 0.0081 15.1 22.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF347 PF03988.12 OAG08829.1 - 3.6 7.8 10.6 1.9 8.7 0.1 3.7 3 1 0 3 3 3 0 Repeat of Unknown Function (DUF347) Cation_efflux PF01545.21 OAG08830.1 - 4.7e-53 179.9 0.0 7e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family Eno-Rase_NADH_b PF12242.8 OAG08830.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rib_hydrolayse PF02267.17 OAG08832.1 - 0.0037 16.7 0.0 0.0049 16.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosyl cyclase Peptidase_S3 PF00944.19 OAG08836.1 - 0.062 13.1 1.0 0.16 11.8 1.0 1.6 1 0 0 1 1 1 0 Alphavirus core protein CC2-LZ PF16516.5 OAG08836.1 - 0.54 10.7 5.7 0.5 10.8 1.4 2.4 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Bacillus_HBL PF05791.11 OAG08836.1 - 0.74 9.6 3.0 0.35 10.7 0.3 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4200 PF13863.6 OAG08836.1 - 2.1 8.8 9.6 3.4 8.1 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RNase_T PF00929.24 OAG08837.1 - 1.3e-08 35.5 0.0 2.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Sec1 PF00995.23 OAG08838.1 - 1.1e-111 374.9 0.0 1.3e-111 374.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2073 PF09846.9 OAG08838.1 - 0.00029 20.6 0.1 0.003 17.4 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2073) Vta1 PF04652.16 OAG08839.1 - 5.9e-50 169.0 6.7 1e-49 168.3 6.7 1.4 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 OAG08839.1 - 6.8e-14 51.3 0.5 6.8e-14 51.3 0.5 2.0 2 0 0 2 2 2 1 Vta1 C-terminal domain Thioredoxin PF00085.20 OAG08840.1 - 7.9e-34 115.7 0.0 3e-26 91.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 OAG08840.1 - 1.2e-06 28.1 0.0 6.6e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 OAG08840.1 - 7.4e-06 26.0 0.0 0.022 14.7 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OAG08840.1 - 0.00015 22.2 6.3 0.23 11.9 0.1 3.6 2 2 1 3 3 3 2 Thioredoxin-like domain TraF PF13728.6 OAG08840.1 - 0.00043 20.2 7.9 0.023 14.5 0.0 3.5 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 OAG08840.1 - 0.0039 17.5 0.0 2.5 8.5 0.0 3.5 2 1 1 3 3 3 1 Thioredoxin-like HyaE PF07449.11 OAG08840.1 - 0.024 14.6 0.0 1.5 8.8 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 OAG08840.1 - 0.047 13.6 0.1 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_3 PF13192.6 OAG08840.1 - 0.056 13.5 2.5 4.1 7.5 0.1 3.1 3 0 0 3 3 3 0 Thioredoxin domain Rib_recp_KP_reg PF05104.12 OAG08840.1 - 4.9 8.2 25.8 1.3 10.1 14.8 2.4 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region adh_short_C2 PF13561.6 OAG08841.1 - 2.3e-52 177.9 0.2 2.8e-52 177.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG08841.1 - 5.9e-36 123.8 0.1 7.5e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG08841.1 - 1.7e-07 31.3 0.1 4.4e-07 30.0 0.1 1.7 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG08841.1 - 0.00035 20.1 0.0 0.00081 18.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG08841.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 OAG08841.1 - 0.078 12.8 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein LVIVD PF08309.11 OAG08842.1 - 0.34 10.3 2.0 2.8 7.3 0.0 2.7 2 1 0 2 2 2 0 LVIVD repeat Coiled-coil_56 PF09813.9 OAG08843.1 - 2.5e-06 27.5 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 OAG08844.1 - 2.9e-62 210.3 0.0 4.3e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) FAD_binding_4 PF01565.23 OAG08845.1 - 1.3e-20 73.6 1.1 4.1e-20 71.9 1.4 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG08845.1 - 3.2e-09 36.7 0.2 7.2e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Sulfate_transp PF00916.20 OAG08846.1 - 1.8 7.2 7.9 0.87 8.3 0.4 2.2 1 1 1 2 2 2 0 Sulfate permease family Sarcolipin PF05366.11 OAG08846.1 - 7.8 6.3 7.4 10 5.9 0.2 2.4 2 0 0 2 2 2 0 Sarcolipin Transp_cyt_pur PF02133.15 OAG08847.1 - 2.5e-90 303.4 35.7 2.9e-90 303.1 35.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 OAG08848.1 - 4.9e-125 417.0 0.5 1.1e-124 415.8 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 OAG08848.1 - 1.9e-32 112.7 0.4 1.5e-27 96.6 0.0 3.3 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG08848.1 - 3.3e-28 98.6 1.4 1.3e-25 90.2 0.4 3.0 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 OAG08848.1 - 6.3e-07 29.2 1.2 2.7e-05 23.8 0.1 2.9 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 OAG08848.1 - 0.00036 19.3 1.3 0.016 13.9 0.0 2.3 2 0 0 2 2 2 2 MutL protein ROK PF00480.20 OAG08848.1 - 0.007 15.9 0.3 0.025 14.1 0.2 2.0 2 0 0 2 2 2 1 ROK family StbA PF06406.11 OAG08848.1 - 0.048 12.9 0.2 5.6 6.1 0.0 2.8 3 1 0 3 3 3 0 StbA protein Mito_carr PF00153.27 OAG08849.1 - 4.3e-58 193.2 2.7 2.5e-20 72.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG08849.1 - 0.54 9.4 4.3 6.6 5.8 0.0 3.1 3 2 0 3 3 3 0 Gammaproteobacterial serine protease DUF2985 PF11204.8 OAG08851.1 - 3.2e-27 94.5 3.9 5.7e-27 93.7 3.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Mucin PF01456.17 OAG08851.1 - 0.5 10.4 22.3 2 8.4 22.3 2.0 1 0 0 1 1 1 0 Mucin-like glycoprotein PBP PF01161.20 OAG08852.1 - 1.7e-16 60.7 0.0 2.1e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MFS_1 PF07690.16 OAG08853.1 - 1.2e-35 123.0 51.0 2.4e-28 99.1 34.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.11 OAG08853.1 - 7.8 5.9 10.6 12 5.3 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) p450 PF00067.22 OAG08854.1 - 1.5e-22 80.0 0.0 5.4e-21 74.9 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 adh_short PF00106.25 OAG08855.1 - 3.8e-21 75.4 1.0 1.2e-19 70.5 1.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG08855.1 - 5.3e-11 42.5 0.3 2.6e-10 40.3 0.3 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG08855.1 - 2e-07 31.1 0.3 3.3e-07 30.4 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF1254 PF06863.12 OAG08855.1 - 0.0037 17.3 0.0 3.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1254) MspA PF09203.11 OAG08856.1 - 0.0081 16.0 5.4 0.0081 16.0 5.4 2.4 1 1 1 2 2 2 2 MspA OMP_b-brl PF13505.6 OAG08856.1 - 0.022 14.9 0.2 0.28 11.3 0.2 2.2 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain OMP_b-brl_2 PF13568.6 OAG08856.1 - 0.041 13.9 0.0 0.21 11.6 0.0 2.1 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF2715 PF10895.8 OAG08856.1 - 0.086 12.5 6.6 0.65 9.6 0.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2715) DUF3575 PF12099.8 OAG08856.1 - 0.093 12.0 0.5 4.3 6.6 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3575) DUF1943 PF09172.11 OAG08856.1 - 0.49 9.6 8.5 1.6 7.9 4.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) OGG_N PF07934.12 OAG08857.1 - 5.7e-35 120.0 0.0 1.1e-34 119.1 0.0 1.5 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 OAG08857.1 - 3.5e-18 66.0 0.0 9.1e-18 64.7 0.0 1.7 1 1 1 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG08857.1 - 5.9e-05 22.7 0.0 0.00016 21.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.22 OAG08858.1 - 5.5e-28 96.6 0.8 1.2e-12 47.4 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG08858.1 - 9.4e-05 22.2 0.1 0.2 11.5 0.0 3.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif CFEM PF05730.11 OAG08859.1 - 3.1e-16 59.2 12.3 5.7e-16 58.4 12.3 1.4 1 0 0 1 1 1 1 CFEM domain WD40 PF00400.32 OAG08861.1 - 1.7e-05 25.5 1.2 0.00027 21.7 0.1 3.2 3 1 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.9 OAG08861.1 - 0.034 14.1 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 OAG08861.1 - 0.15 12.4 0.0 35 4.8 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Chitin_synth_2 PF03142.15 OAG08862.1 - 6.1e-290 962.3 0.5 1e-289 961.6 0.1 1.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG08862.1 - 2e-14 54.0 2.0 6.9e-14 52.2 2.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG08862.1 - 3.4e-11 43.5 0.0 6.2e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG08862.1 - 0.00052 19.5 0.0 0.0066 15.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG08862.1 - 0.0091 15.8 0.0 0.097 12.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Peptidase_M56 PF05569.11 OAG08862.1 - 0.042 13.0 2.9 0.1 11.8 0.0 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 Sel1 PF08238.12 OAG08863.1 - 5.4e-39 131.8 33.0 9.9e-07 29.2 0.4 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 OAG08863.1 - 0.044 14.4 8.2 3.3 8.5 0.2 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG08863.1 - 5.4 7.8 17.0 3.5 8.3 1.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 OAG08864.1 - 6.3e-15 55.2 0.0 8.2e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAG08864.1 - 3e-05 23.0 0.0 7.8e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF4381 PF14316.6 OAG08865.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SKG6 PF08693.10 OAG08865.1 - 0.13 11.7 1.0 0.27 10.7 1.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HhH-GPD PF00730.25 OAG08867.1 - 4.3e-05 23.9 1.0 0.0028 18.1 0.0 2.9 2 2 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein SesA PF17107.5 OAG08867.1 - 4.9e-05 23.5 9.3 0.00012 22.2 1.2 2.9 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases APG17 PF04108.12 OAG08867.1 - 0.0019 17.4 3.5 0.0019 17.4 3.5 2.4 1 1 0 2 2 2 1 Autophagy protein Apg17 Helo_like_N PF17111.5 OAG08867.1 - 0.025 13.9 9.7 0.1 12.0 9.7 2.0 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Macoilin PF09726.9 OAG08867.1 - 0.11 11.0 9.8 0.15 10.6 9.8 1.2 1 0 0 1 1 1 0 Macoilin family COG2 PF06148.11 OAG08867.1 - 0.13 12.4 11.3 0.4 10.8 0.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tho1_MOS11_C PF18592.1 OAG08867.1 - 0.41 10.5 2.0 7.8 6.4 0.2 2.7 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain DUF948 PF06103.11 OAG08867.1 - 0.79 10.0 15.5 11 6.4 2.3 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Zw10 PF06248.13 OAG08867.1 - 0.82 8.2 15.6 0.2 10.2 6.1 2.1 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 Spc7 PF08317.11 OAG08867.1 - 1.1 8.1 17.7 0.28 10.0 4.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ApoLp-III PF07464.11 OAG08867.1 - 1.9 8.6 15.1 0.73 9.9 6.2 2.7 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) MCPsignal PF00015.21 OAG08867.1 - 3 7.6 10.1 1.4 8.7 4.5 2.6 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.12 OAG08867.1 - 9.7 6.2 16.6 1.9 8.5 6.4 2.9 1 1 2 3 3 3 0 Laminin Domain II Tmemb_14 PF03647.13 OAG08868.1 - 1.2e-22 80.4 6.9 1.4e-22 80.2 6.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.16 OAG08869.1 - 4.1e-52 175.1 4.0 4.7e-52 174.9 4.0 1.0 1 0 0 1 1 1 1 DAD family DUF4389 PF14333.6 OAG08869.1 - 0.034 14.1 0.4 0.056 13.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Aminotran_3 PF00202.21 OAG08870.1 - 8.9e-89 298.0 0.0 1.1e-88 297.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG08870.1 - 6.1e-05 22.4 0.0 0.0003 20.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II GRDB PF07355.12 OAG08870.1 - 0.048 12.9 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) AAA_12 PF13087.6 OAG08871.1 - 0.046 13.3 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 OAG08873.1 - 1.4e-20 73.8 0.0 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08873.1 - 1.4e-07 31.1 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 OAG08873.1 - 5.9e-06 26.8 0.1 1.2e-05 25.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Kinase-like PF14531.6 OAG08873.1 - 0.0059 15.9 0.0 0.0078 15.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Ank_3 PF13606.6 OAG08873.1 - 0.0067 16.8 0.3 16 6.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OAG08873.1 - 0.024 15.1 0.3 1.7 9.2 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat CMD PF02627.20 OAG08874.1 - 1.9e-06 27.8 1.3 2e-06 27.7 0.3 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family tRNA-synt_2c PF01411.19 OAG08875.1 - 3.5e-216 719.0 0.0 3.5e-216 719.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OAG08875.1 - 3.2e-18 65.6 0.5 8.8e-18 64.1 0.5 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OAG08875.1 - 2.2e-09 37.8 2.6 2.9e-09 37.5 0.6 2.4 2 0 0 2 2 2 1 DHHA1 domain RCR PF12273.8 OAG08877.1 - 1e-08 35.9 17.8 2.3e-08 34.7 17.8 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red zf-HC5HC2H_2 PF13832.6 OAG08878.1 - 5.3e-20 71.6 32.0 7.4e-19 67.9 2.3 4.6 4 1 0 4 4 4 3 PHD-zinc-finger like domain BAH PF01426.18 OAG08878.1 - 4.8e-17 61.9 0.3 1.1e-16 60.8 0.3 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 OAG08878.1 - 7.8e-15 54.9 36.1 1.6e-13 50.7 3.7 4.8 4 0 0 4 4 4 3 PHD-like zinc-binding domain PHD PF00628.29 OAG08878.1 - 2e-12 46.8 57.0 3.1e-06 27.0 8.1 6.5 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 OAG08878.1 - 2.8e-08 33.2 4.3 2.8e-08 33.2 4.3 5.4 6 0 0 6 6 6 1 PHD-finger DUF4166 PF13761.6 OAG08878.1 - 0.033 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) C1_1 PF00130.22 OAG08878.1 - 0.47 10.4 51.7 0.073 13.0 5.6 5.6 5 1 1 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF5539 PF17693.1 OAG08879.1 - 0.015 14.9 0.4 0.022 14.4 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Macoilin PF09726.9 OAG08880.1 - 0.35 9.4 2.2 0.44 9.0 2.2 1.0 1 0 0 1 1 1 0 Macoilin family ResIII PF04851.15 OAG08881.1 - 3e-21 76.2 0.0 1.9e-20 73.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG08881.1 - 3.5e-20 72.4 0.3 1.3e-19 70.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG08881.1 - 6.5e-17 61.9 0.0 7.8e-16 58.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OAG08881.1 - 0.0086 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 OAG08881.1 - 0.01 16.1 0.0 0.038 14.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF3043 PF11241.8 OAG08881.1 - 0.12 12.4 1.9 0.38 10.8 1.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Rhodanese PF00581.20 OAG08882.1 - 0.00045 20.7 0.1 0.0017 18.8 0.1 1.9 1 1 0 1 1 1 1 Rhodanese-like domain ERO1 PF04137.15 OAG08883.1 - 2.9e-135 451.0 0.0 3.7e-135 450.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PRY PF13765.6 OAG08883.1 - 0.12 12.0 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 SPRY-associated domain p450 PF00067.22 OAG08884.1 - 2.3e-71 240.9 0.0 3.6e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG08886.1 - 1.1e-09 37.7 0.1 4.6e-09 35.7 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG08886.1 - 7.1e-06 26.2 14.7 2.7e-05 24.4 7.9 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAG08886.1 - 0.0032 17.8 17.7 0.12 12.9 4.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 OAG08886.1 - 0.0033 17.7 10.2 0.15 12.5 1.5 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG08886.1 - 0.0067 17.2 15.3 0.45 11.5 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG08886.1 - 0.0073 16.6 10.0 0.081 13.2 1.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 OAG08886.1 - 0.2 11.9 3.4 0.42 10.9 3.4 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 OAG08886.1 - 2 8.6 3.7 4.8 7.4 3.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 OAG08886.1 - 3.6 7.6 9.4 2.2 8.2 0.5 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Mito_carr PF00153.27 OAG08887.1 - 2.4e-51 171.6 0.7 8.9e-19 67.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CoA_transf_3 PF02515.17 OAG08888.1 - 1.1e-127 426.1 0.0 1.3e-127 425.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III HgmA PF04209.13 OAG08889.1 - 4.1e-141 470.5 0.0 4.9e-141 470.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Lyase_1 PF00206.20 OAG08890.1 - 1.9e-45 155.6 0.0 3.4e-45 154.8 0.0 1.4 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAG08890.1 - 4.2e-22 78.5 0.1 2.1e-20 73.0 0.0 2.5 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Thiolase_N PF00108.23 OAG08891.1 - 7.5e-73 245.1 0.4 3.9e-71 239.5 0.3 2.0 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG08891.1 - 9.6e-45 151.2 0.2 2.1e-44 150.1 0.1 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG08891.1 - 5e-05 23.0 1.1 0.00018 21.2 0.7 2.0 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain CoA_trans PF01144.23 OAG08892.1 - 4.7e-94 313.8 7.3 5.8e-55 186.0 1.3 2.2 2 0 0 2 2 2 2 Coenzyme A transferase Fe-ADH PF00465.19 OAG08892.1 - 1.1e-70 238.3 0.5 2e-70 237.4 0.5 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG08892.1 - 2.7e-17 63.3 0.1 6.1e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase NAD_binding_11 PF14833.6 OAG08893.1 - 7.3e-26 90.8 0.0 1.2e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 OAG08893.1 - 2.8e-21 76.3 0.0 4e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.6 OAG08894.1 - 5.9e-16 58.9 0.0 8e-13 48.7 0.0 2.1 1 1 1 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 OAG08894.1 - 3.7e-06 26.6 0.0 5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG08894.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG08894.1 - 0.05 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG08895.1 - 3.4e-28 98.4 0.0 3.8e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG08895.1 - 1.2e-24 87.2 0.0 1.3e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3240 PF11582.8 OAG08895.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) COesterase PF00135.28 OAG08896.1 - 8.6e-56 189.9 0.0 1.1e-55 189.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG08896.1 - 5.5e-06 26.4 0.6 7.6e-05 22.7 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG08896.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lactamase_B PF00753.27 OAG08897.1 - 2.7e-07 30.8 0.3 8.6e-07 29.1 0.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG08897.1 - 0.0047 16.5 0.0 0.0084 15.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.22 OAG08898.1 - 8.5e-54 183.0 0.0 1e-53 182.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG08899.1 - 1.7e-49 168.7 41.7 1.7e-49 168.7 41.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily RNA_pol_Rpb4 PF03874.16 OAG08900.1 - 2e-16 60.4 0.0 2.9e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 RhoGAP PF00620.27 OAG08901.1 - 1.8e-32 112.3 0.3 4.4e-32 111.0 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 OAG08901.1 - 1.5e-26 92.4 34.5 1.8e-11 44.1 5.0 5.2 5 0 0 5 5 5 4 LIM domain T2SSE PF00437.20 OAG08901.1 - 0.1 11.7 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IBR PF01485.21 OAG08903.1 - 4.7e-16 58.8 20.3 9.7e-09 35.3 4.7 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Methyltransf_25 PF13649.6 OAG08904.1 - 1.8e-14 54.2 0.0 3.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG08904.1 - 2e-11 44.4 0.0 3.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG08904.1 - 1.5e-10 41.0 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG08904.1 - 6.4e-10 39.7 0.0 1.2e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG08904.1 - 1.2e-07 31.7 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG08904.1 - 2e-05 24.0 0.0 3.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OAG08904.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 OAG08904.1 - 0.038 13.5 0.0 2.8 7.4 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 OAG08904.1 - 0.21 11.7 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 OAG08904.1 - 0.24 10.9 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Tyrosinase PF00264.20 OAG08905.1 - 1.1e-37 130.4 4.7 1.1e-37 130.4 4.7 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAG08905.1 - 1.4e-16 61.3 0.0 3.6e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Tyosinase C-terminal domain DUF1451 PF07295.11 OAG08905.1 - 0.006 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon containing domain LANC_like PF05147.13 OAG08906.1 - 2.3e-34 118.5 0.0 8.3e-34 116.7 0.0 1.7 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein EphA2_TM PF14575.6 OAG08907.1 - 0.14 13.0 0.0 0.34 11.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 OAG08907.1 - 0.67 9.9 3.1 1.6 8.8 3.1 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Cupin_1 PF00190.22 OAG08908.1 - 7.5e-36 123.0 0.0 4.4e-18 65.3 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAG08908.1 - 1.1e-22 79.5 0.9 5.2e-11 42.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG08908.1 - 1.8e-07 30.8 0.1 0.00074 19.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAG08908.1 - 6.3e-05 22.9 0.2 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 OAG08908.1 - 0.0087 15.8 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Cupin SBP56 PF05694.11 OAG08909.1 - 5.4e-08 32.1 0.0 6e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 OAG08909.1 - 0.035 13.4 0.0 2.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 OAG08909.1 - 0.045 14.3 3.1 0.099 13.2 0.3 2.7 2 0 0 2 2 2 0 PQQ-like domain SGL PF08450.12 OAG08909.1 - 0.12 12.0 0.0 2.9 7.4 0.0 2.4 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DMRT-like PF15791.5 OAG08910.1 - 1.1 9.7 3.1 2.1 8.8 2.4 1.7 1 1 1 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 DUF1996 PF09362.10 OAG08912.1 - 2.5e-79 266.5 4.0 3.3e-79 266.2 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FSH1 PF03959.13 OAG08913.1 - 6e-29 101.2 0.0 7.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 OAG08913.1 - 0.027 14.4 0.2 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold SKG6 PF08693.10 OAG08914.1 - 0.022 14.2 1.3 0.052 13.0 1.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RIFIN PF02009.16 OAG08914.1 - 0.037 13.9 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Rifin Glycophorin_A PF01102.18 OAG08914.1 - 0.069 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Glycophorin A YbgS PF13985.6 OAG08915.1 - 0.02 15.1 0.2 0.025 14.8 0.2 1.3 1 0 0 1 1 1 0 YbgS-like protein SH3_9 PF14604.6 OAG08917.1 - 1.5e-29 101.5 3.2 1.9e-15 56.5 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAG08917.1 - 5.6e-27 93.1 2.8 6.7e-13 48.0 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 OAG08917.1 - 2.8e-18 65.3 0.0 2.3e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 OAG08917.1 - 5.5e-15 55.2 0.0 9.8e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box PF00646.33 OAG08918.1 - 0.00013 21.8 0.1 0.00027 20.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain Peptidase_C12 PF01088.21 OAG08920.1 - 5.5e-53 179.8 0.0 6.3e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Stn1 PF10451.9 OAG08920.1 - 0.19 10.6 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Smoothelin PF12510.8 OAG08920.1 - 6.2 6.9 6.3 27 4.9 0.1 3.2 3 0 0 3 3 3 0 Smoothelin cytoskeleton protein Arylsulfotran_2 PF14269.6 OAG08922.1 - 2.2e-61 207.9 0.4 2.8e-61 207.5 0.4 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG08922.1 - 2.2e-18 66.3 0.2 7.1e-17 61.4 0.3 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF202 PF02656.15 OAG08923.1 - 2.6e-16 59.8 3.1 2.6e-16 59.8 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Phage_holin_8 PF16931.5 OAG08924.1 - 0.0022 18.0 0.6 0.0028 17.6 0.6 1.3 1 0 0 1 1 1 1 Putative phage holin Epimerase PF01370.21 OAG08925.1 - 3e-15 56.4 0.0 4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG08925.1 - 1e-08 34.6 0.0 1.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAG08925.1 - 1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG08925.1 - 7.3e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG08925.1 - 0.013 15.8 0.0 0.086 13.1 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Topoisom_I_N PF02919.15 OAG08928.1 - 2.2e-97 324.7 3.8 2.2e-97 324.7 3.8 3.4 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 OAG08928.1 - 6.7e-97 323.3 2.3 6.7e-97 323.3 2.3 2.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 OAG08928.1 - 1.3e-33 114.8 0.8 4e-33 113.2 0.8 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF2931 PF11153.8 OAG08928.1 - 0.024 14.4 0.2 0.07 12.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) ATP-synt PF00231.19 OAG08929.1 - 7.7e-79 265.3 1.5 9.3e-79 265.0 1.5 1.0 1 0 0 1 1 1 1 ATP synthase RNA_pol_A_bac PF01000.26 OAG08931.1 - 2e-24 86.1 0.0 3.6e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAG08931.1 - 6.9e-20 70.3 0.0 9.9e-20 69.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 OAG08932.1 - 1.1e-124 415.0 0.0 1.4e-124 414.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 OAG08932.1 - 0.00011 21.2 0.0 0.00022 20.3 0.0 1.5 1 1 0 1 1 1 1 Nickel-dependent hydrogenase Mucin-like PF16058.5 OAG08933.1 - 0.16 12.1 10.3 9.9 6.3 9.1 2.9 1 1 0 1 1 1 0 Mucin-like DUF4551 PF15087.6 OAG08934.1 - 8.5 5.1 17.5 11 4.7 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CorA PF01544.18 OAG08935.1 - 0.00068 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FAIM1 PF06905.13 OAG08935.1 - 0.0055 16.4 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) E1-E2_ATPase PF00122.20 OAG08935.1 - 0.08 12.5 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Bromo_TP PF07524.13 OAG08935.1 - 0.13 12.3 0.1 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Bromodomain associated Peptidase_M14 PF00246.24 OAG08937.1 - 1.4e-75 254.8 0.0 1.9e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OAG08937.1 - 0.00025 21.4 0.0 0.00053 20.3 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide EthD PF07110.11 OAG08938.1 - 0.00011 23.2 1.9 0.00047 21.2 1.9 1.8 1 1 0 1 1 1 1 EthD domain DUF4516 PF14990.6 OAG08939.1 - 0.17 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) Cutinase PF01083.22 OAG08942.1 - 3.3e-35 121.6 3.6 3.7e-35 121.5 3.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG08942.1 - 0.00034 20.2 0.6 0.00075 19.1 0.1 1.7 1 1 1 2 2 2 1 PE-PPE domain Palm_thioest PF02089.15 OAG08942.1 - 0.022 14.6 0.1 0.027 14.3 0.1 1.3 1 1 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 OAG08942.1 - 0.028 13.9 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Rapsyn_N PF10579.9 OAG08942.1 - 0.068 13.3 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region DUF900 PF05990.12 OAG08942.1 - 0.077 12.5 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) VirJ PF06057.11 OAG08942.1 - 0.18 11.7 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Methyltransf_23 PF13489.6 OAG08943.1 - 8.5e-21 74.5 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG08943.1 - 2.7e-11 44.0 0.0 7.4e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG08943.1 - 1.2e-09 38.6 0.0 2.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG08943.1 - 1.1e-07 32.5 0.0 6.4e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG08943.1 - 3.1e-05 23.8 0.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 OAG08943.1 - 0.0059 16.2 0.0 0.02 14.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OAG08943.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 OAG08943.1 - 0.016 15.3 0.0 0.099 12.7 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase CMAS PF02353.20 OAG08943.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 OAG08943.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 OAG08943.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 OAG08943.1 - 0.22 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FAD_binding_3 PF01494.19 OAG08944.1 - 1.1e-18 67.6 1.4 8.2e-11 41.7 0.3 2.5 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 OAG08944.1 - 1.4e-06 27.6 0.2 3.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAG08944.1 - 0.0001 22.4 0.1 0.00022 21.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG08944.1 - 0.0041 16.4 0.0 0.074 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG08944.1 - 0.035 13.3 0.1 0.069 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAG08944.1 - 0.036 13.1 0.2 0.17 10.9 0.2 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAG08944.1 - 0.04 14.5 0.1 0.29 11.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG08944.1 - 0.041 12.6 0.0 1.2 7.8 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAG08944.1 - 0.054 12.8 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG08944.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase wnt PF00110.19 OAG08945.1 - 0.7 9.4 2.4 1.6 8.2 2.4 1.7 1 1 0 1 1 1 0 wnt family Phyto_Pns9_10 PF05878.11 OAG08947.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 STT3 PF02516.14 OAG08949.1 - 4.1e-142 474.5 33.0 1.6e-137 459.4 30.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit zf-C2H2 PF00096.26 OAG08952.1 - 4.9e-05 23.6 24.4 0.099 13.1 0.3 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type DUF5010_C PF18099.1 OAG08952.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 DUF5010 C-terminal domain DUF629 PF04780.12 OAG08952.1 - 2.1 6.8 5.5 1.2 7.6 3.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF629) FOXP-CC PF16159.5 OAG08952.1 - 6 7.6 14.5 1.9 9.2 2.4 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain SPC25 PF06703.11 OAG08954.1 - 1.1e-55 187.9 0.1 1.3e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 OAG08955.1 - 3.4e-58 196.1 1.7 4.3e-58 195.8 1.7 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EI24 PF07264.11 OAG08955.1 - 0.024 14.9 0.5 0.041 14.1 0.5 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) zf-C2H2 PF00096.26 OAG08956.1 - 0.0099 16.3 10.5 2.5 8.7 0.5 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG08956.1 - 0.55 10.6 6.7 2.4 8.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAG08956.1 - 0.71 10.9 16.7 0.19 12.7 0.5 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-BED PF02892.15 OAG08956.1 - 6.6 6.8 8.1 9.3 6.4 0.1 2.9 2 1 0 2 2 2 0 BED zinc finger HET PF06985.11 OAG08958.1 - 3.6e-22 79.3 0.0 9.3e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX PF00293.28 OAG08959.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ribonuclease_T2 PF00445.18 OAG08960.1 - 1.2e-35 123.4 0.1 1.6e-35 123.0 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Lactamase_B_2 PF12706.7 OAG08961.1 - 4.1e-36 124.4 0.0 1.8e-35 122.3 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG08961.1 - 9.8e-13 48.3 0.0 2.5e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG08961.1 - 0.069 13.1 0.6 0.58 10.1 0.5 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily NACHT PF05729.12 OAG08963.1 - 3.1e-09 37.0 1.6 4.6e-09 36.4 0.4 2.0 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG08963.1 - 1e-05 26.0 3.3 6.9e-05 23.3 0.0 3.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG08963.1 - 0.00051 20.3 3.1 0.0031 17.8 0.0 3.3 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.27 OAG08963.1 - 0.0048 17.4 1.3 0.1 13.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Lectin_N PF03954.14 OAG08963.1 - 0.0054 16.5 4.7 0.27 11.0 1.5 3.0 3 0 0 3 3 3 1 Hepatic lectin, N-terminal domain PSK_trans_fac PF07704.11 OAG08963.1 - 0.015 16.0 1.5 0.048 14.4 0.8 2.3 1 1 1 2 2 2 0 Rv0623-like transcription factor dNK PF01712.19 OAG08963.1 - 0.039 13.8 0.5 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2075 PF09848.9 OAG08963.1 - 0.048 12.9 2.2 0.83 8.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 OAG08963.1 - 0.058 13.3 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OAG08963.1 - 0.06 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAG08963.1 - 0.073 13.5 0.2 0.32 11.4 0.0 2.2 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.6 OAG08963.1 - 0.12 13.0 1.4 0.34 11.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 OAG08963.1 - 0.17 12.0 0.1 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 OAG08963.1 - 0.22 11.6 1.5 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OAG08963.1 - 0.54 10.7 0.0 0.54 10.7 0.0 3.0 2 1 1 3 3 2 0 AAA domain Apolipoprotein PF01442.18 OAG08963.1 - 1.5 8.6 12.7 5.7 6.8 9.7 2.8 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain HVSL PF09749.9 OAG08965.1 - 7.5e-79 264.5 0.0 9e-79 264.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein S_layer_N PF05123.12 OAG08965.1 - 0.13 12.1 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 S-layer like family, N-terminal region Pal1 PF08316.11 OAG08966.1 - 6.4e-11 43.2 0.1 1.8e-10 41.7 0.1 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein Peroxin-13_N PF04088.13 OAG08967.1 - 2e-52 177.3 0.4 2.9e-52 176.8 0.4 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 OAG08967.1 - 2.8e-07 30.0 0.0 6.8e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG08967.1 - 6.3e-07 29.0 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAG08967.1 - 8.7e-05 22.3 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 OAG08967.1 - 0.064 13.7 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain SKG6 PF08693.10 OAG08969.1 - 0.00014 21.1 2.5 0.00032 20.1 2.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 OAG08969.1 - 0.00038 20.0 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Adeno_E3_CR2 PF02439.15 OAG08969.1 - 0.006 16.3 0.3 0.011 15.5 0.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM51 PF15345.6 OAG08969.1 - 0.07 13.0 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 DUF347 PF03988.12 OAG08969.1 - 0.092 12.9 0.3 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 OAG08969.1 - 0.14 13.0 0.0 0.28 12.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 OAG08969.1 - 0.87 9.7 4.0 1.5 9.0 4.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NOA36 PF06524.12 OAG08972.1 - 0.22 10.8 11.9 0.28 10.5 11.9 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 OAG08972.1 - 4.6 6.6 11.9 6 6.2 11.9 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 OAG08972.1 - 5.8 6.7 11.5 9.9 6.0 11.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 OAG08972.1 - 5.9 5.0 11.9 6.5 4.8 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 OAG08972.1 - 7.2 5.6 19.3 13 4.9 19.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Methyltransf_11 PF08241.12 OAG08973.1 - 5.2e-07 30.2 0.0 1.1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG08973.1 - 0.0088 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG08973.1 - 0.0097 16.6 0.0 0.026 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ribul_P_3_epim PF00834.19 OAG08974.1 - 4.5e-62 209.0 0.0 3.3e-61 206.1 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 OAG08974.1 - 0.012 15.3 0.1 0.025 14.2 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 OAG08974.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 OAG08974.1 - 0.039 13.4 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein LSM PF01423.22 OAG08975.1 - 3.3e-16 58.7 0.0 5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG08975.1 - 0.041 14.0 0.0 0.056 13.6 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain SKG6 PF08693.10 OAG08977.1 - 0.0016 17.8 4.3 0.0028 17.0 4.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain HET PF06985.11 OAG08978.1 - 2.5e-33 115.5 0.0 4.6e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MtrG PF04210.13 OAG08978.1 - 0.014 15.2 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4003 PF13170.6 OAG08978.1 - 0.028 13.8 0.1 0.9 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) FTCD_C PF04961.12 OAG08978.1 - 0.039 13.7 0.2 0.062 13.1 0.2 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase TolA_bind_tri PF16331.5 OAG08978.1 - 0.04 14.0 0.8 0.04 14.0 0.8 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1043 PF06295.12 OAG08978.1 - 0.26 11.3 0.7 0.43 10.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) HrpB7 PF09486.10 OAG08978.1 - 0.32 11.4 2.4 0.54 10.6 2.4 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) COesterase PF00135.28 OAG08979.1 - 7.4e-62 209.9 0.0 9.9e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG08979.1 - 7.2e-06 26.0 0.1 8.4e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold zf-CCCH PF00642.24 OAG08981.1 - 1.2e-23 82.5 30.9 3.7e-06 26.7 0.2 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG08981.1 - 2.6e-21 74.9 29.3 2.2e-06 27.5 1.8 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 OAG08981.1 - 1.5e-11 44.9 27.5 0.00029 21.5 0.4 5.5 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 OAG08981.1 - 1.1e-10 41.1 35.7 0.00011 21.9 0.5 5.3 5 0 0 5 5 5 5 CCCH-type zinc finger zf-CCCH_3 PF15663.5 OAG08981.1 - 5.5e-05 23.3 17.2 9.3e-05 22.6 8.6 2.8 1 1 1 2 2 2 2 Zinc-finger containing family GRP PF07172.11 OAG08981.1 - 1.1 10.0 7.8 1.6 9.5 7.8 1.2 1 0 0 1 1 1 0 Glycine rich protein family Glyco_hydro_18 PF00704.28 OAG08982.1 - 2.9e-75 253.9 0.0 3.4e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vps53_N PF04100.12 OAG08983.1 - 1.2e-107 360.2 5.4 1.2e-107 360.2 5.4 1.5 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 OAG08983.1 - 7.7e-09 35.2 8.1 1.6e-08 34.2 8.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 OAG08983.1 - 0.0027 17.6 1.3 0.0071 16.2 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Zw10 PF06248.13 OAG08983.1 - 0.0073 14.9 11.6 0.012 14.2 7.3 2.2 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 VPS53_C PF16854.5 OAG08983.1 - 0.031 14.2 0.0 0.15 11.9 0.0 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus APG6_N PF17675.1 OAG08983.1 - 0.05 14.1 8.3 0.097 13.2 6.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region COG2 PF06148.11 OAG08983.1 - 0.65 10.1 12.0 0.24 11.5 5.6 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.15 OAG08983.1 - 2 8.2 5.3 1.3 8.9 1.3 2.8 2 1 1 3 3 3 0 Septum formation initiator Nup54 PF13874.6 OAG08983.1 - 9.2 6.4 8.8 14 5.8 5.8 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 APH PF01636.23 OAG08985.1 - 9.8e-40 137.0 0.0 1.4e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG08985.1 - 0.009 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 OAG08985.1 - 0.056 13.0 0.0 9.2 5.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 OAG08985.1 - 0.083 12.2 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain CKS PF01111.19 OAG08987.1 - 6.4e-35 119.2 1.8 1e-34 118.6 1.8 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit zf-C2H2_4 PF13894.6 OAG08988.1 - 1.9e-05 25.1 32.9 0.29 12.1 2.1 7.0 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG08988.1 - 0.01 16.1 2.4 0.01 16.1 2.4 5.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OAG08988.1 - 0.03 14.8 8.1 1.8 9.1 0.1 4.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 OAG08988.1 - 0.067 13.9 3.8 1.1 10.0 0.2 3.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 OAG08988.1 - 0.081 12.9 0.2 0.081 12.9 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger C1_1 PF00130.22 OAG08988.1 - 0.32 10.9 11.5 19 5.2 0.4 4.3 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.15 OAG08988.1 - 0.67 10.0 16.7 29 4.8 0.0 5.0 4 1 0 4 4 4 0 BED zinc finger zf-C2H2_2 PF12756.7 OAG08988.1 - 4.6 7.6 17.2 4.3 7.7 0.1 4.9 4 1 1 5 5 5 0 C2H2 type zinc-finger (2 copies) Fungal_trans PF04082.18 OAG08989.1 - 7.9e-16 57.9 0.1 1.2e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG08989.1 - 0.00011 22.2 6.5 0.00018 21.6 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 OAG08990.1 - 2.6e-61 207.3 0.0 1.2e-39 136.3 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG08990.1 - 6.6e-28 97.7 0.0 1.2e-21 77.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 OAG08990.1 - 6.1e-13 48.9 0.0 1.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 OAG08990.1 - 4.6e-08 32.7 0.0 6.4e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAG08990.1 - 3.3e-05 23.9 0.6 0.002 18.1 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family PAS_9 PF13426.7 OAG08990.1 - 0.00017 21.8 0.0 0.00047 20.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OAG08990.1 - 0.00047 20.1 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold Haspin_kinase PF12330.8 OAG08990.1 - 0.0057 15.7 0.0 0.014 14.3 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain PAS_4 PF08448.10 OAG08990.1 - 0.0094 16.2 0.1 0.044 14.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold Kdo PF06293.14 OAG08990.1 - 0.011 15.0 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAG08990.1 - 0.041 13.5 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OAG08990.1 - 0.13 11.3 0.1 0.29 10.1 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 OAG08990.1 - 1.4 9.7 5.9 7 7.4 2.0 3.7 2 1 0 2 2 2 0 Protein kinase C terminal domain Hva1_TUDOR PF11160.8 OAG08991.1 - 2.7e-18 65.8 1.8 2.7e-18 65.8 1.8 3.0 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain LAP1C PF05609.12 OAG08991.1 - 2 7.4 21.5 2.4 7.2 21.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 OAG08991.1 - 2.5 6.6 19.3 2.8 6.4 19.3 1.3 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 OAG08991.1 - 7.7 5.6 10.4 10 5.2 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Abhydrolase_1 PF00561.20 OAG08993.1 - 7.2e-12 45.5 0.0 2.5e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG08993.1 - 4.8e-07 30.6 0.0 6.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG08993.1 - 4.7e-06 26.0 0.0 9.2e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG08993.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Ndr family COPIIcoated_ERV PF07970.12 OAG08994.1 - 5.5e-88 294.5 0.2 4.8e-87 291.4 0.2 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAG08994.1 - 3e-30 104.4 0.0 9.8e-30 102.8 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sulfate_transp PF00916.20 OAG08995.1 - 4.7e-108 361.3 19.9 6e-108 361.0 19.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG08995.1 - 1.1e-06 28.3 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OAG08995.1 - 2.9e-05 24.4 2.3 2.9e-05 24.4 2.3 2.9 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 OAG08995.1 - 7.8 6.5 9.0 0.33 10.9 0.3 3.1 3 0 0 3 3 3 0 Stannin transmembrane RabGAP-TBC PF00566.18 OAG08996.1 - 4.5e-35 121.2 0.1 1.8e-27 96.4 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain LMBR1 PF04791.16 OAG09000.1 - 9.1e-19 67.7 3.4 9.1e-19 67.7 3.4 2.4 1 1 1 2 2 2 2 LMBR1-like membrane protein Deltameth_res PF16020.5 OAG09000.1 - 0.11 12.4 0.1 0.87 9.5 0.1 2.7 1 0 0 1 1 1 0 Deltamethrin resistance CPSF_A PF03178.15 OAG09001.1 - 2.4e-90 303.1 0.0 4.6e-90 302.2 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OAG09001.1 - 1.7e-30 106.2 0.0 4e-30 104.9 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Lipocalin PF00061.23 OAG09001.1 - 0.16 12.1 0.1 0.44 10.7 0.1 1.7 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Rax2 PF12768.7 OAG09002.1 - 8e-64 215.0 0.4 6.4e-63 212.1 0.0 2.9 4 0 0 4 4 4 1 Cortical protein marker for cell polarity Phage_holin_2_4 PF16082.5 OAG09002.1 - 0.24 11.2 1.0 0.94 9.3 1.0 2.0 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 OAG09005.1 - 1.7e-46 158.8 58.8 2.8e-45 154.8 57.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG09005.1 - 5.6e-17 61.4 21.0 5.6e-17 61.4 21.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG09005.1 - 4.3e-13 48.9 14.0 4.3e-13 48.9 14.0 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter RhgB_N PF09284.10 OAG09009.1 - 3.1e-87 292.3 0.5 4.5e-87 291.7 0.5 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 OAG09009.1 - 7.5e-33 113.7 0.6 2.7e-32 111.9 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 OAG09009.1 - 1.7e-16 59.8 3.9 1.7e-16 59.8 3.9 2.6 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OAG09009.1 - 2.1e-05 24.7 0.6 2.1e-05 24.7 0.6 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4278 PF14105.6 OAG09009.1 - 0.025 15.0 0.6 7 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4278) SpaA PF17802.1 OAG09009.1 - 1.4 9.3 6.8 14 6.1 0.5 2.9 3 0 0 3 3 3 0 Prealbumin-like fold domain SnoaL PF07366.12 OAG09010.1 - 0.00028 20.7 0.1 0.00045 20.0 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase FGAR-AT_linker PF18072.1 OAG09010.1 - 0.036 14.6 0.5 10 6.7 0.0 2.5 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain TspO_MBR PF03073.15 OAG09011.1 - 3.7e-46 156.5 11.8 4.6e-46 156.2 11.8 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.8 OAG09012.1 - 1.8e-27 95.7 8.2 1.8e-27 95.7 8.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 OAG09012.1 - 3.1e-14 53.8 1.8 4.5e-14 53.3 0.6 1.9 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 OAG09012.1 - 1.1e-11 44.4 0.2 3.4e-11 42.7 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3818 PF12825.7 OAG09013.1 - 7.7e-132 439.4 3.4 1.3e-131 438.6 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAG09013.1 - 8.3e-40 135.8 1.3 1.6e-39 134.8 1.3 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 OAG09013.1 - 9.3e-12 44.9 0.0 5.9e-11 42.4 0.0 2.3 1 1 0 1 1 1 1 PX domain GFD1 PF17331.2 OAG09013.1 - 0.041 14.1 2.9 0.15 12.3 2.9 2.0 1 0 0 1 1 1 0 GFD1 mRNA transport factor Cupin_8 PF13621.6 OAG09014.1 - 8.1e-14 51.9 0.0 5.7e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OAG09014.1 - 1.1e-08 35.5 0.0 6.7e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 OAG09014.1 - 2.3e-08 33.8 0.0 7e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG09014.1 - 1.4e-07 31.2 0.0 3.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF3984 PF13136.6 OAG09014.1 - 0.2 11.0 0.7 0.61 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) DEAD PF00270.29 OAG09015.1 - 1.8e-45 154.9 1.2 2.8e-45 154.2 1.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG09015.1 - 1.7e-31 108.9 0.1 1.7e-30 105.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG09015.1 - 9.7e-07 28.9 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAG09015.1 - 0.00054 19.7 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG09015.1 - 0.0015 18.8 0.8 0.0094 16.3 0.5 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 OAG09015.1 - 0.0078 15.6 0.3 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 OAG09015.1 - 0.014 15.7 0.4 0.056 13.7 0.4 2.0 1 1 0 1 1 1 0 AAA domain IL17R_D_N PF16742.5 OAG09015.1 - 0.062 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D fragilysinNterm PF16376.5 OAG09015.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of fragilysin UvrD-helicase PF00580.21 OAG09015.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain NUDIX PF00293.28 OAG09016.1 - 1.2e-09 38.4 0.1 3.5e-09 36.8 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain PX PF00787.24 OAG09017.1 - 5.1e-18 65.1 1.2 1.5e-17 63.6 1.1 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 OAG09017.1 - 3.3e-10 39.9 7.3 2e-06 27.5 1.0 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 OAG09017.1 - 0.0006 19.6 1.9 0.12 12.1 0.1 2.3 2 0 0 2 2 2 2 BAR domain of APPL family Sec34 PF04136.15 OAG09017.1 - 0.12 12.2 1.0 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 Sec34-like family ADK PF00406.22 OAG09018.1 - 1.6e-36 125.7 0.0 4.4e-19 69.1 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 OAG09018.1 - 5.3e-17 62.5 0.1 8.5e-11 42.4 0.0 2.4 2 1 1 3 3 3 2 AAA domain ADK_lid PF05191.14 OAG09018.1 - 2.5e-15 56.1 0.0 5.7e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAG09018.1 - 1.5e-06 28.8 0.0 1.6e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG09018.1 - 0.00065 19.9 0.1 0.021 15.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 OAG09018.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 OAG09018.1 - 0.16 12.2 0.1 0.64 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAG09018.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI LETM1 PF07766.13 OAG09019.1 - 1.1e-103 346.3 0.3 1.1e-103 346.3 0.3 1.8 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 OAG09019.1 - 1.3e-05 24.8 0.0 0.0017 18.0 0.0 3.4 3 0 0 3 3 3 1 SAP domain BPL_N PF09825.9 OAG09019.1 - 9.7 5.2 10.6 0.45 9.5 0.1 2.5 2 1 0 2 2 2 0 Biotin-protein ligase, N terminal Nop14 PF04147.12 OAG09020.1 - 3.2e-235 783.4 38.5 8e-188 626.6 21.4 2.1 1 1 1 2 2 2 2 Nop14-like family DUF5324 PF17258.2 OAG09020.1 - 0.0074 16.0 0.6 0.029 14.1 0.6 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5324) SasG_E PF17041.5 OAG09020.1 - 0.018 15.1 2.1 1 9.4 0.1 2.6 2 0 0 2 2 2 0 E domain HEAT_2 PF13646.6 OAG09021.1 - 0.076 13.4 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 HEAT repeats DUF3879 PF12995.7 OAG09021.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) Carb_kinase PF01256.17 OAG09022.1 - 8.9e-57 192.4 0.3 1.1e-56 192.1 0.3 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 OAG09022.1 - 0.00054 19.4 0.1 0.00081 18.9 0.1 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 OAG09022.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase ATP-grasp_6 PF18419.1 OAG09022.1 - 0.084 12.5 0.1 4.5 7.0 0.0 3.0 3 1 0 3 3 3 0 ATP-grasp-like domain Lactamase_B PF00753.27 OAG09023.1 - 1.5e-17 64.3 3.8 2e-17 63.9 3.8 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG09023.1 - 1.3e-05 24.8 0.1 1.8e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MogR_DNAbind PF12181.8 OAG09023.1 - 0.007 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 DNA binding domain of the motility gene repressor (MogR) PDEase_II PF02112.15 OAG09023.1 - 0.19 10.8 0.2 0.29 10.2 0.2 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II zf-BED PF02892.15 OAG09025.1 - 0.0021 18.1 1.9 1.7 8.7 0.6 2.7 2 0 0 2 2 2 2 BED zinc finger DUF5012 PF16404.5 OAG09025.1 - 0.065 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) Lipase_chap PF03280.14 OAG09025.1 - 0.18 11.7 3.5 0.46 10.4 3.5 1.7 1 1 0 1 1 1 0 Proteobacterial lipase chaperone protein zf-C2H2_4 PF13894.6 OAG09025.1 - 1.2 10.1 4.5 6.4 7.9 0.5 3.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 OAG09025.1 - 2 8.8 5.4 1.3 9.4 1.6 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CAP_GLY PF01302.25 OAG09026.1 - 5.1e-15 55.2 0.4 1.1e-14 54.2 0.4 1.6 1 0 0 1 1 1 1 CAP-Gly domain NPV_P10 PF05531.12 OAG09026.1 - 0.00034 21.0 6.9 0.2 12.2 0.2 3.0 4 0 0 4 4 2 2 Nucleopolyhedrovirus P10 protein CLIP1_ZNF PF16641.5 OAG09026.1 - 0.017 15.0 10.5 0.51 10.3 1.1 2.6 2 0 0 2 2 2 0 CLIP1 zinc knuckle Spc7 PF08317.11 OAG09026.1 - 0.051 12.5 34.0 0.051 12.5 10.1 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein DHR10 PF18595.1 OAG09026.1 - 0.18 11.8 36.2 0.051 13.6 10.5 3.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain PI3K_P85_iSH2 PF16454.5 OAG09026.1 - 0.2 11.2 21.0 0.21 11.2 3.1 3.5 3 1 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BST2 PF16716.5 OAG09026.1 - 0.43 11.2 19.1 1.1 9.9 0.8 4.3 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 FAM76 PF16046.5 OAG09026.1 - 0.53 9.6 10.1 2.4 7.4 0.4 3.0 3 0 0 3 3 3 0 FAM76 protein Fez1 PF06818.15 OAG09026.1 - 0.85 10.0 33.4 0.18 12.3 12.5 3.2 2 1 1 3 3 3 0 Fez1 Baculo_PEP_C PF04513.12 OAG09026.1 - 1.1 9.3 2.3 4.6 7.3 0.3 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 OAG09026.1 - 1.8 6.4 2.6 1.1 7.1 0.9 1.5 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 OAG09026.1 - 2 8.5 10.3 1.4 9.0 2.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HemX PF04375.14 OAG09026.1 - 2.3 7.5 17.0 0.33 10.2 2.0 3.2 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Phage_GP20 PF06810.11 OAG09026.1 - 2.8 7.7 15.6 3.6 7.4 1.4 3.9 4 0 0 4 4 4 0 Phage minor structural protein GP20 AAA_13 PF13166.6 OAG09026.1 - 4 6.0 18.7 1.4 7.5 8.3 2.4 1 1 1 2 2 2 0 AAA domain Fmp27_WPPW PF10359.9 OAG09026.1 - 9.2 5.0 17.2 0.5 9.2 0.8 3.0 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain APH PF01636.23 OAG09027.1 - 2e-38 132.7 0.0 3.7e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG09027.1 - 7.1e-05 22.3 0.0 0.00019 20.8 0.0 1.7 1 1 1 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 OAG09027.1 - 0.00022 20.9 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OAG09027.1 - 0.0016 18.1 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 OAG09027.1 - 0.0082 15.5 0.0 0.058 12.7 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 OAG09027.1 - 0.03 13.2 0.0 0.81 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 OAG09027.1 - 0.032 13.5 0.0 0.79 8.9 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase LSM PF01423.22 OAG09028.1 - 6.5e-21 73.8 0.3 7.2e-21 73.7 0.3 1.0 1 0 0 1 1 1 1 LSM domain RasGAP_C PF03836.15 OAG09029.1 - 0.0022 18.1 0.3 0.0058 16.8 0.3 1.6 1 0 0 1 1 1 1 RasGAP C-terminus KIX_2 PF16987.5 OAG09029.1 - 0.17 11.9 1.8 0.52 10.3 1.0 2.1 2 0 0 2 2 2 0 KIX domain RlaP PF10127.9 OAG09029.1 - 0.45 10.1 4.8 0.38 10.3 3.0 1.7 1 1 1 2 2 2 0 RNA repair pathway DNA polymerase beta family Cmc1 PF08583.10 OAG09030.1 - 3.2e-16 59.1 3.2 3.7e-16 58.9 3.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF5131 PF07505.11 OAG09030.1 - 0.067 12.6 0.5 0.076 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) Prefoldin_2 PF01920.20 OAG09031.1 - 5e-25 87.5 8.8 6e-25 87.3 8.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 OAG09031.1 - 0.012 15.5 9.0 0.64 9.9 9.0 2.2 1 1 0 1 1 1 0 Prefoldin subunit SAS-6_N PF16531.5 OAG09031.1 - 0.065 13.8 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal CLZ PF16526.5 OAG09031.1 - 0.085 13.2 5.6 0.43 11.0 0.2 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Com_YlbF PF06133.11 OAG09031.1 - 0.21 12.2 7.8 1.7 9.3 0.2 2.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA p25-alpha PF05517.12 OAG09031.1 - 0.27 11.4 3.8 9 6.4 0.1 2.1 2 0 0 2 2 2 0 p25-alpha DUF2205 PF10224.9 OAG09031.1 - 0.76 9.8 7.9 1.2 9.2 0.7 2.1 2 0 0 2 2 2 0 Short coiled-coil protein NUDE_C PF04880.13 OAG09032.1 - 2 8.9 4.6 1.6 9.2 3.4 1.4 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region CBFD_NFYB_HMF PF00808.23 OAG09033.1 - 6.1e-26 90.5 2.9 2.7e-25 88.4 1.8 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG09033.1 - 2.5e-06 27.9 0.5 4.8e-06 27.0 0.5 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 OAG09033.1 - 0.00083 19.3 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 OAG09033.1 - 0.0017 18.4 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 OAG09033.1 - 0.02 15.0 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 OAG09033.1 - 0.076 13.5 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DHHC PF01529.20 OAG09034.1 - 3.6e-33 114.5 6.3 6.6e-33 113.7 6.3 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 OAG09034.1 - 0.059 13.3 0.4 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Glyco_transf_22 PF03901.17 OAG09035.1 - 5.3e-40 137.9 21.6 6.6e-40 137.6 21.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SUI1 PF01253.22 OAG09036.1 - 1e-25 90.1 0.1 2e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TAP_C PF03943.13 OAG09037.1 - 1.4e-09 37.4 0.1 2.9e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 OAG09037.1 - 0.00025 20.8 0.0 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain LRR_4 PF12799.7 OAG09037.1 - 0.034 14.6 2.5 0.049 14.1 1.0 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) RecG_wedge PF17191.4 OAG09037.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RecG wedge domain DUF1462 PF07315.11 OAG09037.1 - 0.095 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) DPPIV_N PF00930.21 OAG09038.1 - 8e-107 357.0 0.4 1.1e-106 356.6 0.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAG09038.1 - 1.3e-57 194.7 1.9 3.2e-57 193.4 1.9 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAG09038.1 - 7.5e-10 38.8 0.7 3.1e-08 33.5 0.1 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAG09038.1 - 5.2e-05 23.0 0.1 0.0002 21.1 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 OAG09038.1 - 0.0018 16.8 0.0 0.055 12.0 0.0 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 OAG09038.1 - 0.0091 14.7 0.0 0.2 10.3 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 OAG09038.1 - 0.028 13.7 0.3 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 OAG09038.1 - 0.047 13.2 0.0 0.25 10.9 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family PD40 PF07676.12 OAG09038.1 - 0.06 13.3 0.3 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SHS2_Rpb7-N PF03876.17 OAG09039.1 - 1.1e-13 51.3 0.0 1.8e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAG09039.1 - 5.1e-12 46.0 0.0 9.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 OAG09039.1 - 9.8e-05 22.6 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 DUF962 PF06127.11 OAG09040.1 - 7.6e-27 93.2 0.0 1.3e-26 92.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.25 OAG09041.1 - 1.9e-73 246.6 0.0 2.8e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OAG09041.1 - 2.2e-47 160.5 0.4 3.9e-47 159.7 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OAG09041.1 - 1.5e-15 57.5 3.0 3.8e-15 56.2 3.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 OAG09041.1 - 0.081 13.1 0.2 1.7 8.9 0.2 2.7 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit FAD_binding_2 PF00890.24 OAG09042.1 - 4.1e-78 263.3 0.2 5e-78 263.0 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 OAG09042.1 - 1.2e-20 73.5 0.9 6.3e-19 67.9 0.0 3.3 5 0 0 5 5 5 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 OAG09042.1 - 1.4e-10 41.3 0.6 8.9e-10 38.7 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG09042.1 - 9.8e-09 35.1 0.3 3.1e-08 33.4 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG09042.1 - 9.3e-08 32.2 0.2 6.6e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG09042.1 - 7e-06 25.5 0.4 2e-05 24.0 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG09042.1 - 8e-06 24.8 0.9 0.0032 16.2 0.1 3.1 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG09042.1 - 1.1e-05 24.8 0.1 0.076 12.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG09042.1 - 0.0002 20.7 0.1 0.028 13.7 0.0 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAG09042.1 - 0.0014 17.8 1.8 0.017 14.2 0.4 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A IF2_N PF04760.15 OAG09042.1 - 0.005 16.6 0.7 0.014 15.2 0.7 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FAD_binding_3 PF01494.19 OAG09042.1 - 0.0058 15.9 0.6 0.013 14.8 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG09042.1 - 0.026 13.8 0.2 0.049 12.9 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OAG09042.1 - 0.11 12.5 0.2 2.4 8.1 0.2 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding Metallophos PF00149.28 OAG09043.1 - 1.4e-07 32.3 1.9 2.4e-07 31.5 1.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-B_box PF00643.24 OAG09044.1 - 0.016 15.3 1.3 0.026 14.7 1.3 1.4 1 0 0 1 1 1 0 B-box zinc finger Fungal_trans PF04082.18 OAG09046.1 - 6.2e-09 35.3 0.3 1.6e-08 33.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09046.1 - 8e-07 29.1 6.9 1.5e-06 28.2 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeS_assembly_P PF01883.19 OAG09048.1 - 2.8e-09 37.0 0.0 5.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein PH_9 PF15410.6 OAG09051.1 - 0.0021 18.4 0.0 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 OAG09051.1 - 0.016 15.7 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 0 PH domain Peptidase_M1_N PF17900.1 OAG09052.1 - 0.0042 17.3 0.1 3.8 7.7 0.0 3.0 3 1 0 3 3 3 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 OAG09052.1 - 0.037 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain p450 PF00067.22 OAG09053.1 - 3.9e-69 233.6 0.0 4.7e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2929 PF11151.8 OAG09054.1 - 0.0089 16.3 0.2 0.017 15.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2929) FR47 PF08445.10 OAG09055.1 - 3.5e-06 26.9 0.0 0.00031 20.7 0.0 2.5 3 0 0 3 3 3 2 FR47-like protein Acetyltransf_3 PF13302.7 OAG09055.1 - 0.12 13.1 0.0 4.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_L10 PF00466.20 OAG09056.1 - 6.6e-26 90.4 0.2 3.1e-25 88.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 OAG09056.1 - 1.1e-23 83.6 6.7 1.1e-23 83.6 6.7 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 OAG09056.1 - 3.7e-21 74.9 0.2 9.1e-21 73.6 0.0 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P TA0956 PF11513.8 OAG09056.1 - 0.012 15.8 0.2 3.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 VirE_N PF08800.10 OAG09056.1 - 0.038 14.1 0.1 0.09 12.9 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain WD40 PF00400.32 OAG09057.1 - 2.6e-07 31.2 3.9 0.00044 21.0 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat KAsynt_C_assoc PF16197.5 OAG09057.1 - 0.065 13.7 0.7 0.39 11.2 0.0 2.4 3 0 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension Lactonase PF10282.9 OAG09057.1 - 0.077 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller BBS2_Mid PF14783.6 OAG09057.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Pyr_redox_2 PF07992.14 OAG09058.1 - 1.1e-40 139.7 0.4 1.3e-40 139.4 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG09058.1 - 8.2e-19 68.0 0.0 1.1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG09058.1 - 9.5e-15 54.9 0.1 2.5e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG09058.1 - 7.1e-06 25.4 0.1 0.0062 15.7 0.0 2.6 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG09058.1 - 0.00065 19.4 0.0 0.53 9.8 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAG09058.1 - 0.045 14.2 0.1 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding LemA PF04011.12 OAG09059.1 - 0.019 14.8 0.6 0.04 13.8 0.6 1.5 1 0 0 1 1 1 0 LemA family Atg14 PF10186.9 OAG09060.1 - 3.9e-66 223.3 0.5 4.9e-66 223.0 0.5 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 OAG09060.1 - 0.0051 16.2 4.6 0.0083 15.5 4.6 1.4 1 0 0 1 1 1 1 FAM76 protein Cob_adeno_trans PF01923.18 OAG09060.1 - 0.036 14.2 0.9 0.097 12.8 0.9 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA_13 PF13166.6 OAG09060.1 - 0.044 12.4 8.5 0.06 12.0 8.5 1.1 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 OAG09060.1 - 0.11 11.7 6.0 0.18 11.1 6.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 OAG09060.1 - 0.2 10.5 13.3 0.3 9.9 13.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_Gp19 PF09355.10 OAG09060.1 - 0.43 11.0 3.7 1.1 9.7 3.7 1.7 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 bZIP_1 PF00170.21 OAG09060.1 - 1.3 9.2 9.8 5.8 7.1 0.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor DHR10 PF18595.1 OAG09060.1 - 4.1 7.5 17.7 1.6 8.8 14.3 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Cys_Met_Meta_PP PF01053.20 OAG09061.1 - 4.3e-139 463.3 0.0 4.9e-139 463.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG09061.1 - 6.4e-09 35.4 0.1 1e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG09061.1 - 3.5e-07 29.9 0.2 7.4e-07 28.8 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAG09061.1 - 1.6e-05 24.1 0.1 2.8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V HET PF06985.11 OAG09065.1 - 9.7e-11 42.2 9.1 2.3e-08 34.5 4.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TauD PF02668.16 OAG09066.1 - 1.4e-48 166.0 2.1 2.2e-48 165.4 2.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAG09066.1 - 0.0001 22.9 0.4 0.00038 21.0 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF971) Mito_carr PF00153.27 OAG09067.1 - 4.7e-63 209.1 5.0 1.5e-20 72.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG09067.1 - 2.7 7.1 6.3 1.3 8.1 0.1 3.2 4 1 0 4 4 4 0 Gammaproteobacterial serine protease Ofd1_CTDD PF10637.9 OAG09068.1 - 6.3e-90 301.0 0.0 1.1e-86 290.3 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OAG09068.1 - 2.8e-24 85.6 0.0 9e-24 84.0 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OAG09068.1 - 2.9e-12 47.3 0.0 7.9e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polysacc_deac_1 PF01522.21 OAG09069.1 - 2.3e-13 50.1 0.0 3.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG09069.1 - 6.5e-07 29.2 0.0 1.4e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Lactonase PF10282.9 OAG09070.1 - 1.3e-66 225.2 0.0 1.7e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ABC_tran PF00005.27 OAG09071.1 - 1.6e-25 90.2 0.0 2.6e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OAG09071.1 - 4e-13 49.3 7.6 4e-13 49.3 7.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 OAG09071.1 - 0.0041 17.0 0.1 0.0074 16.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 OAG09071.1 - 0.0079 15.4 12.0 0.019 14.1 12.0 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein MMR_HSR1 PF01926.23 OAG09071.1 - 0.06 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 OAG09071.1 - 0.11 11.9 0.1 0.99 8.8 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG09071.1 - 0.11 12.2 0.7 0.27 11.0 0.7 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG09071.1 - 0.12 12.1 0.0 1.1 9.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 OAG09071.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Dickkopf_N PF04706.12 OAG09071.1 - 4.8 7.7 12.9 4.7 7.8 5.4 2.6 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Exo5 PF09810.9 OAG09072.1 - 0.11 12.0 0.0 0.72 9.3 0.0 1.9 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Imm30 PF15565.6 OAG09073.1 - 0.14 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 30 MutS_V PF00488.21 OAG09075.1 - 3.5e-73 245.6 0.0 6.7e-73 244.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG09075.1 - 5.4e-42 144.2 4.2 1.8e-41 142.5 4.2 1.9 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAG09075.1 - 8.6e-22 77.5 0.0 3.3e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAG09075.1 - 2.2e-10 40.9 0.2 2.2e-08 34.5 0.0 3.2 3 1 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 OAG09075.1 - 0.0064 16.8 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 OAG09075.1 - 1.1 9.7 5.8 2.2 8.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain URO-D PF01208.17 OAG09076.1 - 2.9e-124 414.7 0.0 3.3e-124 414.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 OAG09077.1 - 1.2e-21 76.5 0.1 1.6e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG09077.1 - 4.4e-19 68.6 0.0 5.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 OAG09077.1 - 8.1e-06 26.0 0.1 0.00036 20.6 0.1 2.0 1 1 0 1 1 1 1 APOBEC2 Bd3614-deam PF14439.6 OAG09077.1 - 3.5e-05 23.9 3.0 0.014 15.4 3.0 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.11 OAG09077.1 - 0.00012 22.0 0.3 0.015 15.2 0.0 2.1 1 1 1 2 2 2 2 APOBEC-like N-terminal domain SNAD4 PF18750.1 OAG09077.1 - 0.00054 20.1 0.0 0.0016 18.5 0.0 1.7 1 1 1 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 OAG09077.1 - 0.00056 20.1 0.0 0.006 16.7 0.0 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 NAD1 PF18778.1 OAG09077.1 - 0.00075 19.6 0.2 0.02 15.0 0.2 2.1 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 OAG09077.1 - 0.013 15.6 0.1 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 APOBEC3 APOBEC4_like PF18774.1 OAG09077.1 - 0.026 14.4 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase XOO_2897-deam PF14440.6 OAG09077.1 - 0.057 13.5 0.2 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase DnaJ_C PF01556.18 OAG09078.1 - 8.8e-40 136.2 0.1 1.1e-39 135.8 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG09078.1 - 5.4e-26 90.5 2.1 9.3e-26 89.7 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG09078.1 - 3.3e-16 59.4 17.5 5.6e-16 58.6 17.5 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF1356 PF07092.12 OAG09078.1 - 0.12 11.7 2.0 2.1 7.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zinc_ribbon_9 PF14369.6 OAG09078.1 - 0.31 11.3 2.9 23 5.3 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon HypA PF01155.19 OAG09078.1 - 0.5 10.4 9.5 0.51 10.4 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 OAG09078.1 - 0.93 9.6 6.5 4.9 7.3 0.7 2.2 1 1 0 2 2 2 0 Zinc-ribbon containing domain Anti-TRAP PF15777.5 OAG09078.1 - 1.1 9.3 15.3 0.46 10.5 1.5 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_ribbon_SprT PF17283.2 OAG09078.1 - 1.2 9.0 4.3 2.4 8.2 1.8 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 OAG09078.1 - 1.6 8.8 8.1 1.7 8.7 2.1 2.3 1 1 1 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 OAG09078.1 - 5.7 7.0 8.3 8.8 6.4 1.5 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain adh_short PF00106.25 OAG09079.1 - 1.6e-29 102.8 0.0 2.5e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG09079.1 - 1.3e-21 77.3 0.0 2.3e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG09079.1 - 0.0072 16.3 0.2 0.22 11.4 0.2 2.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG09079.1 - 0.067 13.0 0.1 0.98 9.2 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 OAG09079.1 - 0.075 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CorA PF01544.18 OAG09080.1 - 1.8e-08 34.1 0.1 2.8e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pirin PF02678.16 OAG09081.1 - 1.1e-29 102.5 0.0 2.2e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 OAG09081.1 - 4.3e-26 91.3 0.0 1.1e-24 86.8 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OAG09081.1 - 1.6e-06 27.7 1.3 1.8e-05 24.4 0.7 2.3 2 0 0 2 2 2 1 Cupin domain Asp PF00026.23 OAG09082.1 - 4.1e-06 26.4 0.0 6.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF4690 PF15756.5 OAG09082.1 - 0.0079 16.8 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage CD34_antigen PF06365.12 OAG09082.1 - 0.13 11.9 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Rax2 PF12768.7 OAG09082.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity F-box PF00646.33 OAG09083.1 - 3.5e-06 26.7 0.0 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG09083.1 - 0.00028 20.7 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like DIOX_N PF14226.6 OAG09084.1 - 2.3e-28 99.3 0.0 3.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG09084.1 - 2.2e-22 79.4 0.1 6.9e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 OAG09085.1 - 0.0025 17.7 0.1 0.0071 16.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like Methyltransf_21 PF05050.12 OAG09085.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase FkbM domain NYD-SP12_N PF15015.6 OAG09085.1 - 0.13 10.6 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal His_Phos_2 PF00328.22 OAG09086.1 - 1.8e-33 116.5 0.0 2.2e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Cupin_2 PF07883.11 OAG09087.1 - 1.8e-06 27.6 0.2 3.6e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Cupin domain DMSP_lyase PF16867.5 OAG09087.1 - 0.0039 16.9 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Fungal_trans PF04082.18 OAG09089.1 - 8.6e-43 146.3 4.2 8.6e-43 146.3 4.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Menin PF05053.13 OAG09089.1 - 0.38 9.1 3.5 0.55 8.5 3.5 1.1 1 0 0 1 1 1 0 Menin Ald_Xan_dh_C2 PF02738.18 OAG09091.1 - 1.7e-197 657.3 0.0 2.4e-197 656.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OAG09091.1 - 2.8e-40 137.9 0.0 5.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 OAG09091.1 - 5e-32 110.1 0.0 9.4e-31 106.1 0.0 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 OAG09091.1 - 4.1e-31 107.6 0.0 8.3e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 OAG09091.1 - 1.7e-25 88.9 0.0 5.1e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 OAG09091.1 - 1e-07 31.8 0.1 1e-07 31.8 0.1 2.6 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF2672 PF10878.8 OAG09091.1 - 0.11 12.5 0.1 0.4 10.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) Oxidored_FMN PF00724.20 OAG09092.1 - 1.9e-86 290.4 0.0 1.2e-84 284.5 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OAG09092.1 - 0.012 15.0 0.1 1.2 8.5 0.0 2.9 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel FAD_binding_3 PF01494.19 OAG09093.1 - 1.5e-09 37.6 0.0 0.0001 21.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG09093.1 - 0.00019 21.1 0.0 0.00036 20.2 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 OAG09093.1 - 0.096 11.7 0.0 0.4 9.7 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Polysacc_deac_1 PF01522.21 OAG09094.1 - 1.4e-18 67.0 0.0 2.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG09094.1 - 2.2e-05 24.2 0.0 6.9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 OAG09094.1 - 0.043 12.2 0.0 0.066 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Amidase PF01425.21 OAG09095.1 - 6.9e-108 361.5 0.0 9e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF5486 PF17588.2 OAG09095.1 - 0.12 12.2 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5486) FAD_binding_3 PF01494.19 OAG09096.1 - 3.6e-81 273.1 0.0 6.2e-81 272.3 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG09096.1 - 2e-30 106.0 0.0 3.9e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 OAG09096.1 - 1.2e-06 28.3 0.0 0.014 15.0 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG09096.1 - 4.7e-06 26.1 0.0 6e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG09096.1 - 9.1e-06 26.2 0.0 0.0027 18.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG09096.1 - 0.00033 19.9 0.0 0.0059 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAG09096.1 - 0.00056 19.1 0.0 0.00098 18.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG09096.1 - 0.0011 17.8 0.0 0.0023 16.7 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG09096.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAG09096.1 - 0.0038 16.6 0.8 0.018 14.4 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG09096.1 - 0.0083 16.3 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG09096.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 OAG09096.1 - 0.021 14.2 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG09096.1 - 0.058 13.5 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Inj_translocase PF16928.5 OAG09096.1 - 0.059 12.8 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome TrkA_N PF02254.18 OAG09096.1 - 0.072 13.3 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAG09096.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG09096.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 OAG09097.1 - 9.8e-31 106.9 28.0 1.3e-30 106.6 28.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Spherulin4 PF12138.8 OAG09098.1 - 2.1e-63 214.2 0.1 2.4e-63 214.0 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Sugar_tr PF00083.24 OAG09099.1 - 1.8e-73 248.0 29.6 4.5e-71 240.1 29.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09099.1 - 7.7e-16 58.0 49.7 9.2e-15 54.4 20.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 OAG09100.1 - 3e-18 66.7 0.0 4.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG09100.1 - 6.9e-18 65.0 0.0 1.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 OAG09102.1 - 2.5e-16 59.8 8.5 0.0082 17.0 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG09102.1 - 2.2e-07 31.0 1.0 0.0088 16.3 0.1 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG09102.1 - 1.2e-05 24.2 1.8 5.7e-05 22.0 0.4 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Macoilin PF09726.9 OAG09104.1 - 0.39 9.2 10.0 0.44 9.0 10.0 1.1 1 0 0 1 1 1 0 Macoilin family CCSAP PF15748.5 OAG09104.1 - 3.4 7.8 12.1 6.2 6.9 12.1 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RIBIOP_C PF04950.12 OAG09105.1 - 0.079 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal CE2_N PF17996.1 OAG09108.1 - 2.9e-14 53.0 0.1 6.8e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 OAG09108.1 - 1.3e-13 51.8 1.2 1.8e-13 51.3 1.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG09108.1 - 8.4e-07 29.2 0.1 1.2e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase F-box-like PF12937.7 OAG09109.1 - 0.00013 21.8 0.1 0.00029 20.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG09109.1 - 0.028 14.3 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.25 OAG09110.1 - 1.1e-38 133.1 0.0 1.1e-20 74.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG09110.1 - 1.3e-16 60.7 0.0 5.4e-07 29.2 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OAG09110.1 - 0.00015 21.7 0.1 0.00025 21.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG09110.1 - 0.082 12.2 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Glyco_hydro_cc PF11790.8 OAG09111.1 - 1.3e-49 169.0 0.0 1.6e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Patatin PF01734.22 OAG09112.1 - 1.1e-24 87.7 0.0 3.2e-24 86.3 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase MBOAT_2 PF13813.6 OAG09113.1 - 1.2e-12 48.0 0.3 2.4e-12 46.9 0.3 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Gpr1_Fun34_YaaH PF01184.19 OAG09113.1 - 0.0079 15.8 3.1 0.53 9.8 0.8 2.3 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family Tyrosinase PF00264.20 OAG09114.1 - 5.4e-48 164.2 6.0 5.4e-48 164.2 6.0 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase WLM PF08325.10 OAG09116.1 - 4.9e-58 196.4 1.0 7.5e-58 195.8 1.0 1.3 1 0 0 1 1 1 1 WLM domain DZR PF12773.7 OAG09116.1 - 9.3e-05 22.4 2.7 0.00032 20.7 2.8 1.8 1 1 0 1 1 1 1 Double zinc ribbon zf-RanBP PF00641.18 OAG09116.1 - 0.0021 17.4 0.4 0.0021 17.4 0.4 3.0 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Zincin_1 PF06262.11 OAG09116.1 - 0.23 11.6 0.8 0.72 10.0 0.4 1.9 2 0 0 2 2 2 0 Zincin-like metallopeptidase PIG-H PF10181.9 OAG09116.1 - 0.25 11.2 0.0 0.48 10.3 0.0 1.4 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component HypA PF01155.19 OAG09116.1 - 0.35 10.9 2.0 17 5.5 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 OAG09116.1 - 1 9.4 6.9 35 4.4 0.0 4.1 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-Sec23_Sec24 PF04810.15 OAG09116.1 - 4.7 7.4 7.5 17 5.5 0.0 2.8 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger DUF1776 PF08643.10 OAG09117.1 - 4.5e-85 285.6 0.0 5.6e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 OAG09117.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase Sel1 PF08238.12 OAG09118.1 - 1.2e-11 44.8 17.1 0.00038 21.0 0.2 4.0 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 OAG09118.1 - 2.2 9.1 8.8 25 5.8 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Cupin_2 PF07883.11 OAG09119.1 - 5.7e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG09119.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) adh_short_C2 PF13561.6 OAG09120.1 - 5.1e-60 202.9 1.1 6.5e-60 202.6 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG09120.1 - 1.3e-54 184.7 0.6 1.7e-54 184.2 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG09120.1 - 2.7e-06 27.4 0.4 4.4e-06 26.7 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG09120.1 - 7.2e-05 22.4 0.4 0.00025 20.6 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG09120.1 - 0.0063 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAG09120.1 - 0.01 15.0 0.1 0.013 14.7 0.1 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG09120.1 - 0.011 15.8 0.2 0.022 14.8 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OAG09120.1 - 0.027 14.6 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IMPDH PF00478.25 OAG09120.1 - 0.047 12.7 0.6 0.07 12.1 0.6 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain THF_DHG_CYH_C PF02882.19 OAG09120.1 - 0.054 12.8 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ribosomal_L26 PF16906.5 OAG09120.1 - 0.14 12.7 0.1 0.66 10.5 0.0 2.0 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal RIFIN PF02009.16 OAG09121.1 - 4.7 7.0 11.3 0.28 11.1 0.2 2.1 2 0 0 2 2 2 0 Rifin zf-C3HC4 PF00097.25 OAG09122.1 - 0.66 9.9 8.1 1.3 9.0 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 OAG09122.1 - 6.8 6.3 7.7 7.8 6.1 4.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding SF3b1 PF08920.10 OAG09124.1 - 5.8e-21 75.2 7.5 2.9e-20 72.9 7.5 2.2 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 OAG09124.1 - 7.9e-12 45.4 12.7 0.29 11.5 0.1 8.2 4 2 5 9 9 9 5 HEAT repeats HEAT PF02985.22 OAG09124.1 - 2.4e-11 42.8 9.4 0.0032 17.6 0.1 9.5 12 0 0 12 12 11 2 HEAT repeat HEAT_EZ PF13513.6 OAG09124.1 - 5e-10 39.7 6.7 0.086 13.4 0.0 7.2 7 1 0 7 7 7 3 HEAT-like repeat Cnd1 PF12717.7 OAG09124.1 - 5.8e-08 32.9 5.1 0.44 10.6 0.0 6.4 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAG09124.1 - 1.9e-06 26.8 0.3 0.32 9.5 0.1 3.5 2 1 1 3 3 3 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OAG09124.1 - 5.6e-06 26.9 3.5 1.6 9.4 0.0 6.0 6 1 0 6 6 6 2 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 OAG09124.1 - 0.0008 19.1 0.3 2.1 8.0 0.0 5.1 4 1 2 6 6 6 1 NUC173 domain UNC45-central PF11701.8 OAG09124.1 - 0.0013 18.7 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 OAG09124.1 - 0.0071 15.9 0.1 1.1 8.7 0.0 3.4 4 0 0 4 4 4 1 CLASP N terminal CRM1_C PF08767.11 OAG09124.1 - 0.032 13.4 0.2 0.081 12.1 0.2 1.7 1 0 0 1 1 1 0 CRM1 C terminal ThiF PF00899.21 OAG09125.1 - 1.7e-63 214.3 0.0 2.3e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OAG09125.1 - 3.1e-27 94.5 0.1 4.7e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OAG09125.1 - 0.00028 21.0 0.7 0.00056 20.0 0.1 1.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 OAG09125.1 - 0.055 13.6 1.4 0.12 12.5 1.4 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.27 OAG09125.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3007 PF11460.8 OAG09125.1 - 0.11 12.7 0.6 20 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) PglD_N PF17836.1 OAG09125.1 - 0.17 12.5 1.0 0.54 10.9 0.4 2.1 1 1 1 2 2 2 0 PglD N-terminal domain Telomere_reg-2 PF10193.9 OAG09126.1 - 3.2e-34 117.6 0.2 1e-32 112.8 0.0 3.4 3 0 0 3 3 3 1 Telomere length regulation protein dUTPase PF00692.19 OAG09127.1 - 6.2e-42 142.3 0.0 8e-42 142.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase ECH_1 PF00378.20 OAG09127.1 - 0.055 12.8 0.1 0.071 12.4 0.1 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Sugar_tr PF00083.24 OAG09128.1 - 2.5e-126 422.2 28.6 2.8e-126 422.0 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09128.1 - 2.1e-23 82.8 25.1 2.1e-23 82.8 25.1 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Phos_pyr_kin PF08543.12 OAG09129.1 - 4.8e-10 39.2 0.0 7.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAG09129.1 - 3.2e-06 26.7 0.4 8.7e-06 25.2 0.0 1.9 3 0 0 3 3 3 1 pfkB family carbohydrate kinase PCNA_N PF00705.18 OAG09130.1 - 2.6e-54 182.3 4.0 2.6e-54 182.3 4.0 1.7 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OAG09130.1 - 2.1e-51 173.4 0.3 2.1e-50 170.2 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 OAG09130.1 - 1.1e-08 34.8 0.1 1.4e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 OAG09130.1 - 3.5e-07 29.6 0.1 0.0038 16.4 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein Rad1 PF02144.16 OAG09130.1 - 4.5e-07 29.2 1.5 0.00012 21.3 1.5 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF5115 PF17142.4 OAG09130.1 - 0.052 13.2 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5115) AMA-1 PF02430.15 OAG09130.1 - 0.065 12.2 0.1 0.11 11.4 0.0 1.3 2 0 0 2 2 2 0 Apical membrane antigen 1 Rab5ip PF07019.12 OAG09131.1 - 8.6e-29 100.0 2.3 1e-28 99.7 2.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) RL11D PF11088.8 OAG09131.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Vezatin PF12632.7 OAG09133.1 - 3.3e-68 230.1 0.0 5.2e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF3176 PF11374.8 OAG09133.1 - 0.09 13.0 2.1 0.23 11.7 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) zf-C2H2_4 PF13894.6 OAG09134.1 - 0.00068 20.3 2.9 0.0012 19.5 0.3 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG09134.1 - 0.0018 18.6 4.9 0.015 15.8 0.2 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type DUF2848 PF11010.8 OAG09134.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) zf-H2C2_2 PF13465.6 OAG09134.1 - 1.2 9.7 3.7 2.1 8.9 0.6 3.0 2 1 0 2 2 2 0 Zinc-finger double domain AAA PF00004.29 OAG09136.1 - 1.2e-40 139.0 0.0 2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG09136.1 - 3e-05 23.7 0.0 7.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OAG09136.1 - 6.5e-05 23.2 0.0 0.0058 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG09136.1 - 0.00011 22.2 0.0 0.00046 20.2 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG09136.1 - 0.00043 20.5 0.0 0.0015 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAG09136.1 - 0.00053 20.4 0.1 0.011 16.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 OAG09136.1 - 0.0015 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAG09136.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAG09136.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG09136.1 - 0.033 13.7 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAG09136.1 - 0.051 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG09136.1 - 0.064 13.2 0.4 11 5.9 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAG09136.1 - 0.066 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OAG09136.1 - 0.069 12.9 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG09136.1 - 0.088 12.5 0.1 0.24 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAG09136.1 - 0.089 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAG09136.1 - 0.1 12.4 0.3 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAG09136.1 - 0.11 13.1 0.0 0.47 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAG09136.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 OAG09137.1 - 2.3e-145 485.0 14.0 2.6e-145 484.8 14.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tnp_DNA_bind PF14706.6 OAG09139.1 - 0.0022 17.8 0.3 0.0034 17.2 0.3 1.3 1 0 0 1 1 1 1 Transposase DNA-binding ELMO_CED12 PF04727.13 OAG09140.1 - 1.5e-45 155.4 0.0 3.1e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 OAG09140.1 - 5.7e-37 127.2 0.2 1.1e-36 126.4 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 OAG09140.1 - 1.1e-13 51.4 0.0 2.6e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) DUF3958 PF13125.6 OAG09140.1 - 0.085 13.1 3.1 0.17 12.1 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Siva PF05458.12 OAG09141.1 - 0.33 10.6 12.3 0.53 9.9 12.3 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) GDP_Man_Dehyd PF16363.5 OAG09143.1 - 2.8e-71 240.6 0.0 3.4e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG09143.1 - 8.3e-56 189.1 0.0 1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG09143.1 - 1.7e-22 79.9 0.0 2e-21 76.4 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG09143.1 - 4.3e-22 78.4 0.0 5.8e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG09143.1 - 1.4e-19 70.3 0.0 1.8e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG09143.1 - 1.1e-14 54.2 0.0 3.3e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OAG09143.1 - 0.00017 21.6 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAG09143.1 - 0.028 13.9 0.0 0.91 8.9 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 OAG09143.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 KR domain ECH_1 PF00378.20 OAG09144.1 - 2.1e-18 66.6 0.0 2.4e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG09144.1 - 4.2e-05 23.2 0.0 5.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase THOC7 PF05615.13 OAG09145.1 - 2.7 8.3 17.0 0.081 13.2 8.9 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 Glyco_hydro_38N PF01074.22 OAG09146.1 - 7.1e-86 288.1 0.1 7.1e-86 288.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OAG09146.1 - 5.1e-54 183.6 0.0 1.8e-53 181.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OAG09146.1 - 4.8e-28 97.1 0.0 1e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OAG09146.1 - 8e-07 29.1 0.0 2.9e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 OAG09146.1 - 0.11 11.7 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 MFS_1 PF07690.16 OAG09147.1 - 6.2e-42 143.8 19.2 6.2e-42 143.8 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 OAG09148.1 - 9.3e-21 73.8 0.3 3.5e-10 40.3 0.1 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAG09148.1 - 2.3e-10 39.9 0.0 0.00022 20.3 0.0 2.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OAG09148.1 - 1.3e-09 38.2 0.0 9.4e-05 22.6 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAG09148.1 - 0.00014 21.7 0.3 0.063 13.2 0.0 2.3 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat gag_pre-integrs PF13976.6 OAG09148.1 - 0.00083 19.2 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 2 GAG-pre-integrase domain Nbas_N PF15492.6 OAG09148.1 - 0.001 18.5 0.1 0.17 11.2 0.0 2.0 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 OAG09148.1 - 0.0065 16.3 0.0 0.17 11.6 0.0 1.9 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.11 OAG09148.1 - 0.01 14.6 0.0 1.1 8.0 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like F-box-like PF12937.7 OAG09149.1 - 0.00011 22.1 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG09149.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain CZB PF13682.6 OAG09149.1 - 0.036 14.5 0.0 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain Abhydro_lipase PF04083.16 OAG09150.1 - 4.6e-19 67.7 0.0 1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAG09150.1 - 8.4e-08 32.2 0.1 2.3e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG09150.1 - 0.0005 19.4 0.0 0.00089 18.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA PF00004.29 OAG09151.1 - 1.4e-53 180.8 0.0 2.2e-44 151.1 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG09151.1 - 7.5e-05 22.4 3.2 0.044 13.6 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 OAG09151.1 - 0.00011 21.9 0.0 0.00045 20.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG09151.1 - 0.00013 22.4 2.5 0.024 15.0 0.0 4.0 3 1 0 4 4 3 1 AAA ATPase domain Parvo_NS1 PF01057.17 OAG09151.1 - 0.00055 19.1 0.0 0.00092 18.4 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 OAG09151.1 - 0.0016 18.8 0.0 0.016 15.6 0.0 2.6 3 0 0 3 3 3 1 RNA helicase AAA_2 PF07724.14 OAG09151.1 - 0.0038 17.4 0.0 0.0094 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OAG09151.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 OAG09151.1 - 0.0089 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAG09151.1 - 0.0093 16.2 0.0 0.044 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAG09151.1 - 0.011 15.4 0.0 0.073 12.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG09151.1 - 0.018 15.2 0.0 0.43 10.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 OAG09151.1 - 0.021 14.8 0.1 0.13 12.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAG09151.1 - 0.025 14.0 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAG09151.1 - 0.026 15.1 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAG09151.1 - 0.026 14.4 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 OAG09151.1 - 0.033 14.2 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OAG09151.1 - 0.039 13.3 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 OAG09151.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 OAG09151.1 - 0.044 14.2 0.1 2.4 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAG09151.1 - 0.085 12.0 0.0 2.9 7.0 0.0 3.1 4 0 0 4 4 4 0 NB-ARC domain PhoH PF02562.16 OAG09151.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OAG09151.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 OAG09151.1 - 0.17 11.9 0.1 1.2 9.2 0.1 2.5 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain PPV_E1_C PF00519.17 OAG09151.1 - 0.28 10.0 0.0 0.5 9.1 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase F-box-like PF12937.7 OAG09152.1 - 0.0038 17.1 0.1 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like Pyr_redox_3 PF13738.6 OAG09153.1 - 8.7e-11 41.6 0.0 0.01 15.1 0.0 3.7 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG09153.1 - 9.1e-11 41.5 0.0 4.1e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG09153.1 - 4.3e-09 36.0 0.0 0.0006 19.1 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG09153.1 - 2.7e-05 23.6 0.0 0.018 14.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG09153.1 - 4.1e-05 23.3 0.4 1.3 8.5 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG09153.1 - 0.002 18.3 0.1 0.069 13.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 OAG09153.1 - 0.0022 17.7 0.0 0.022 14.4 0.0 2.5 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 OAG09153.1 - 0.0024 18.4 0.0 7.7 7.2 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG09153.1 - 0.0044 16.1 0.0 0.034 13.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG09153.1 - 0.0059 15.4 0.0 0.031 13.0 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG09153.1 - 0.018 14.2 0.0 0.068 12.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAG09153.1 - 0.029 14.4 4.4 0.48 10.4 0.2 3.9 4 1 1 5 5 5 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG09153.1 - 0.043 13.9 0.1 3.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 OAG09153.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Staph_opine_DH PF10100.9 OAG09153.1 - 0.12 11.0 0.0 1.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Staphylopine dehydrogenase Thi4 PF01946.17 OAG09153.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 OAG09153.1 - 0.15 12.3 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain T2SSM_b PF10741.9 OAG09153.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b FAM176 PF14851.6 OAG09154.1 - 0.022 14.4 0.9 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 FAM176 family AA_permease_2 PF13520.6 OAG09158.1 - 1.5e-58 198.6 17.1 4.1e-58 197.2 17.1 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG09158.1 - 6.1e-13 48.2 20.8 1.9e-12 46.6 14.8 2.6 2 1 0 2 2 2 2 Amino acid permease ArAE_1_C PF11728.8 OAG09159.1 - 0.03 14.3 0.0 0.086 12.8 0.0 1.8 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Mis14 PF08641.12 OAG09159.1 - 0.09 13.1 1.0 11 6.3 0.1 2.6 3 0 0 3 3 3 0 Kinetochore protein Mis14 like Abhydrolase_1 PF00561.20 OAG09162.1 - 1e-17 64.6 0.0 4.2e-16 59.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG09162.1 - 7.3e-14 52.9 1.2 9e-14 52.6 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG09162.1 - 2.1e-12 46.8 0.2 1e-11 44.6 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 OAG09162.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase HET PF06985.11 OAG09163.1 - 8.3e-17 61.9 1.0 1.5e-15 57.8 1.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acetyltransf_1 PF00583.25 OAG09164.1 - 0.00028 21.1 0.0 0.0005 20.3 0.0 1.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG09164.1 - 0.00044 20.6 0.0 0.002 18.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG09164.1 - 0.0044 17.0 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG09164.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein CorA PF01544.18 OAG09165.1 - 4.7e-05 22.8 1.7 0.00055 19.3 1.7 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ArsP_1 PF03773.13 OAG09165.1 - 0.065 12.4 0.8 0.42 9.7 1.3 1.8 1 1 1 2 2 2 0 Predicted permease AAA_assoc_2 PF16193.5 OAG09165.1 - 0.15 12.4 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain Pkinase PF00069.25 OAG09166.1 - 2.8e-13 49.9 0.0 4.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ferritin PF00210.24 OAG09166.1 - 0.16 11.9 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Ferritin-like domain MFS_1 PF07690.16 OAG09167.1 - 2.4e-37 128.7 47.5 8.8e-37 126.8 47.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG09167.1 - 2.4e-11 42.8 20.7 4.3e-11 41.9 20.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CrgA PF06781.12 OAG09167.1 - 8.8 6.5 6.9 4 7.6 0.6 3.2 3 0 0 3 3 3 0 Cell division protein CrgA TENA_THI-4 PF03070.16 OAG09169.1 - 3.8e-05 23.6 0.1 0.043 13.6 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Sacchrp_dh_NADP PF03435.18 OAG09170.1 - 1.9e-15 57.3 0.0 3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 OAG09170.1 - 2.5e-05 24.2 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OAG09170.1 - 0.04 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.18 OAG09171.1 - 9.8e-05 22.4 10.7 9.8e-05 22.4 10.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 OAG09171.1 - 0.019 15.4 3.4 0.019 15.4 3.4 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 OAG09171.1 - 0.022 14.6 3.3 0.073 13.0 3.3 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Zn_clus PF00172.18 OAG09172.1 - 0.074 13.2 7.7 0.044 13.9 5.4 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_14 PF13428.6 OAG09173.1 - 6.4e-11 42.1 13.5 0.0072 17.1 0.0 7.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG09173.1 - 9.4e-09 34.7 2.8 0.043 13.9 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG09173.1 - 6e-06 26.7 1.5 0.12 12.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG09173.1 - 1.7e-05 24.4 0.7 5.6 7.0 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG09173.1 - 2.5e-05 24.1 0.3 0.83 10.0 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG09173.1 - 4.6e-05 23.5 0.2 0.85 10.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG09173.1 - 0.0004 20.8 1.4 4.6 8.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG09173.1 - 0.056 14.1 16.6 2.5 8.8 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Macoilin PF09726.9 OAG09173.1 - 1.9 7.0 9.8 3 6.3 9.8 1.2 1 0 0 1 1 1 0 Macoilin family RIX1 PF08167.12 OAG09174.1 - 3.9e-52 176.7 11.1 7.6e-52 175.8 11.1 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis NUP PF06516.11 OAG09174.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) adh_short PF00106.25 OAG09177.1 - 4.1e-32 111.2 0.0 5.9e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG09177.1 - 5.4e-22 78.5 0.0 7.3e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG09177.1 - 9e-11 42.0 0.0 1.3e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG09177.1 - 1.1e-06 28.3 0.2 3.2e-06 26.8 0.1 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG09177.1 - 0.00011 21.4 0.0 0.00014 21.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG09177.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG09177.1 - 0.0037 16.5 0.0 1.6 7.9 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein NmrA PF05368.13 OAG09177.1 - 0.0042 16.7 0.0 0.0094 15.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 OAG09177.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 OAG09177.1 - 0.0093 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 OAG09177.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG09177.1 - 0.039 14.4 0.0 0.07 13.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG09177.1 - 0.053 12.9 0.0 0.093 12.1 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 OAG09177.1 - 0.084 13.5 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 OAG09177.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.15 OAG09177.1 - 0.2 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MMM1 PF10296.9 OAG09179.1 - 6.4e-135 449.5 0.0 7.6e-135 449.2 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 WHIM1 PF15612.6 OAG09180.1 - 5.3e-06 25.8 0.0 9.7e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.6 OAG09180.1 - 0.089 13.3 2.3 3 8.4 2.3 2.6 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif TB2_DP1_HVA22 PF03134.19 OAG09183.1 - 1.1e-26 92.5 8.4 1.1e-26 92.5 8.4 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.15 OAG09184.1 - 1.3e-28 99.5 0.0 9.3e-28 96.7 0.0 2.3 2 0 0 2 2 2 1 RFX DNA-binding domain FMN_bind_2 PF04299.12 OAG09188.1 - 2.6e-58 196.5 0.1 3.2e-58 196.1 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Ploopntkinase1 PF18748.1 OAG09189.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 B3_4 PF03483.17 OAG09191.1 - 1.2e-23 83.7 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain Sugar_tr PF00083.24 OAG09192.1 - 7e-127 424.0 20.7 8e-127 423.8 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09192.1 - 8.6e-21 74.2 21.9 8.6e-21 74.2 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltr_RsmB-F PF01189.17 OAG09194.1 - 1.8e-76 256.3 0.0 2.7e-76 255.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OAG09194.1 - 5e-08 33.3 0.0 1.2e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OAG09194.1 - 0.099 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF2431 PF10354.9 OAG09194.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Blt1 PF12754.7 OAG09195.1 - 2.9e-44 151.0 0.6 4.5e-44 150.4 0.6 1.3 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 OAG09195.1 - 8.8e-19 66.8 0.2 1.7e-18 66.0 0.2 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 OAG09195.1 - 5.6e-05 22.8 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG09195.1 - 0.03 14.2 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Cofilin_ADF PF00241.20 OAG09196.1 - 4.6e-40 136.2 0.2 5.2e-40 136.0 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.24 OAG09197.1 - 1.8e-84 284.1 14.2 2.9e-84 283.5 14.2 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family MARVEL PF01284.23 OAG09198.1 - 0.004 17.2 12.1 0.008 16.2 12.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF5373 PF17343.2 OAG09198.1 - 0.29 11.0 4.3 0.23 11.3 3.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5373) Zip PF02535.22 OAG09198.1 - 0.36 10.0 2.4 0.31 10.2 0.8 1.7 1 1 1 2 2 2 0 ZIP Zinc transporter DUF3273 PF11677.8 OAG09198.1 - 1.7 7.9 7.6 0.58 9.4 4.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3273) GST_N_2 PF13409.6 OAG09199.1 - 2.3e-17 63.0 0.0 4.6e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG09199.1 - 5.1e-17 61.7 0.1 3.9e-16 58.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG09199.1 - 2.1e-05 24.6 0.1 4.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG09199.1 - 4.4e-05 23.6 0.0 7.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG09199.1 - 0.017 15.5 0.0 0.18 12.2 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAG09199.1 - 0.08 12.8 0.9 0.16 11.8 0.3 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAG09199.1 - 0.13 12.5 0.0 0.87 9.8 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin PEP_mutase PF13714.6 OAG09200.1 - 2.7e-42 144.9 0.2 3.3e-42 144.6 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG09200.1 - 2.2e-18 66.0 0.2 3.2e-18 65.5 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.11 OAG09201.1 - 1.7e-43 148.8 12.3 2.2e-43 148.4 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) F-box_4 PF15966.5 OAG09202.1 - 0.002 18.0 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 OAG09202.1 - 0.016 15.0 0.1 0.064 13.2 0.1 2.1 1 0 0 1 1 1 0 F-box domain RXLR_WY PF18634.1 OAG09202.1 - 0.095 12.6 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain F-box-like PF12937.7 OAG09202.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 OAG09203.1 - 2.6e-33 115.4 38.2 2.6e-33 115.4 38.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Acyltransferase PF01553.21 OAG09204.1 - 7.1e-28 96.9 0.0 1.1e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAG09204.1 - 1.7e-14 53.6 0.0 3.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 OAG09205.1 - 6.5e-45 153.6 0.0 8.7e-44 149.9 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAG09205.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain BRE1 PF08647.11 OAG09206.1 - 3.4e-23 81.5 6.7 3.4e-23 81.5 6.7 7.3 7 1 1 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 OAG09206.1 - 1.6e-09 37.5 9.3 2.8e-09 36.7 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG09206.1 - 3.3e-09 36.5 7.7 6e-09 35.6 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG09206.1 - 3e-07 30.2 10.8 5.7e-07 29.3 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG09206.1 - 3.5e-07 30.4 7.8 6.4e-07 29.6 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG09206.1 - 7.6e-07 29.1 6.3 1.4e-06 28.2 6.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OAG09206.1 - 7.7e-07 28.9 6.3 1.5e-06 27.9 6.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG09206.1 - 9.1e-06 25.5 10.9 1.8e-05 24.6 10.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ATG16 PF08614.11 OAG09206.1 - 0.0009 19.5 20.0 0.0009 19.5 20.0 5.3 1 1 4 6 6 5 1 Autophagy protein 16 (ATG16) zf-rbx1 PF12678.7 OAG09206.1 - 0.0047 17.2 6.2 0.019 15.3 6.2 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF1272 PF06906.11 OAG09206.1 - 0.0075 16.3 4.6 0.021 14.9 4.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) DivIC PF04977.15 OAG09206.1 - 0.011 15.4 0.4 0.011 15.4 0.4 8.8 5 2 6 11 11 11 0 Septum formation initiator zf-RING_6 PF14835.6 OAG09206.1 - 0.013 15.3 3.5 0.025 14.5 3.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OAG09206.1 - 0.013 15.6 6.7 0.026 14.7 6.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAG09206.1 - 0.022 14.5 4.4 0.051 13.4 4.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OAG09206.1 - 0.074 13.1 7.1 0.16 12.0 7.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-H2C2_2 PF13465.6 OAG09206.1 - 0.17 12.4 0.9 3.3 8.3 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain FAD_SOX PF18371.1 OAG09206.1 - 0.19 12.1 0.0 0.19 12.1 0.0 3.4 3 1 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase zf-C2H2 PF00096.26 OAG09206.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.7 5 0 0 5 5 4 0 Zinc finger, C2H2 type FYVE PF01363.21 OAG09206.1 - 2 8.6 9.9 76 3.5 10.4 2.7 1 1 1 2 2 2 0 FYVE zinc finger APG6_N PF17675.1 OAG09206.1 - 2.2 8.8 89.1 2.2 8.8 6.9 7.0 2 1 6 8 8 8 0 Apg6 coiled-coil region Myb_DNA-bind_3 PF12776.7 OAG09206.1 - 6.9 7.7 11.4 0.24 12.4 0.3 4.2 2 1 3 5 5 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG09207.1 - 2.2e-20 72.3 1.1 2.2e-20 72.3 1.1 2.9 2 1 1 3 3 3 1 Myb DNA-binding like Exonuc_VII_L PF02601.15 OAG09207.1 - 0.099 12.2 12.8 0.12 11.9 2.4 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Rit1_C PF17184.4 OAG09208.1 - 5e-104 347.6 0.0 6.5e-104 347.2 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 OAG09208.1 - 5.6e-28 97.4 0.0 9.5e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain PNRC PF15365.6 OAG09210.1 - 6.1e-09 35.4 5.5 6.1e-09 35.4 5.5 4.6 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 OAG09212.1 - 2.9e-25 88.3 13.1 4e-25 87.9 13.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG09212.1 - 3.6e-17 62.2 10.0 4.7e-17 61.8 10.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OAG09212.1 - 2.6e-06 27.7 14.8 9.3e-05 22.7 14.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG09212.1 - 9.2e-05 22.2 3.5 9.2e-05 22.2 3.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG09212.1 - 0.0015 18.4 11.9 0.025 14.4 11.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG09212.1 - 0.19 11.7 11.0 0.56 10.1 4.7 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG09212.1 - 0.34 10.7 15.9 28 4.6 15.9 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 OAG09212.1 - 0.44 10.6 7.7 1.6 8.8 7.7 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 OAG09212.1 - 0.54 10.5 9.3 2.8 8.2 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OAG09212.1 - 0.62 9.7 14.9 92 2.8 14.9 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type SPC12 PF06645.13 OAG09213.1 - 3.2e-29 100.8 0.3 3.8e-29 100.6 0.3 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) LPG_synthase_TM PF03706.13 OAG09213.1 - 0.0018 17.9 1.3 0.0022 17.6 1.3 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region MerC PF03203.14 OAG09213.1 - 0.011 16.2 0.2 0.013 15.9 0.2 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein XK-related PF09815.9 OAG09213.1 - 0.049 12.7 0.0 0.057 12.5 0.0 1.0 1 0 0 1 1 1 0 XK-related protein DUF3040 PF11239.8 OAG09213.1 - 0.077 13.3 0.8 0.096 13.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CorA PF01544.18 OAG09214.1 - 5.2e-45 154.0 0.0 7.2e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UQ_con PF00179.26 OAG09215.1 - 8.4e-38 129.2 0.1 1.1e-37 128.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG09215.1 - 0.15 12.4 1.1 0.25 11.6 1.1 1.7 1 1 0 1 1 1 0 RWD domain NOA36 PF06524.12 OAG09215.1 - 3.3 7.0 9.5 4.6 6.5 9.5 1.2 1 0 0 1 1 1 0 NOA36 protein ABC_membrane PF00664.23 OAG09217.1 - 2.4e-55 188.1 28.1 1.4e-35 123.3 8.4 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG09217.1 - 8.1e-54 181.9 0.0 1.8e-31 109.4 0.0 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG09217.1 - 1.6e-08 34.2 0.0 0.014 14.8 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG09217.1 - 2.4e-07 30.9 0.1 0.024 14.4 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAG09217.1 - 3.7e-05 24.3 4.1 0.0016 19.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 OAG09217.1 - 5.8e-05 23.1 0.1 0.072 13.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OAG09217.1 - 8.2e-05 23.0 0.1 0.51 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAG09217.1 - 9.7e-05 22.4 0.3 0.074 13.1 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 OAG09217.1 - 0.00034 19.8 0.0 0.016 14.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 OAG09217.1 - 0.0004 20.1 0.2 0.6 9.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG09217.1 - 0.00048 20.4 0.4 2.2 8.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 OAG09217.1 - 0.00057 20.0 1.6 0.099 12.7 0.0 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain Zeta_toxin PF06414.12 OAG09217.1 - 0.004 16.4 1.1 1.6 8.0 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_25 PF13481.6 OAG09217.1 - 0.0042 16.7 0.4 0.51 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAG09217.1 - 0.0044 16.6 1.3 0.35 10.4 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 OAG09217.1 - 0.0051 16.6 0.0 2.4 7.8 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_30 PF13604.6 OAG09217.1 - 0.011 15.5 2.7 3.8 7.2 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 OAG09217.1 - 0.015 15.7 0.3 14 6.2 0.1 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OAG09217.1 - 0.017 14.6 0.1 8.1 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 OAG09217.1 - 0.024 13.6 0.9 1.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.23 OAG09217.1 - 0.04 14.0 0.6 0.68 10.0 0.0 2.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 OAG09217.1 - 0.045 13.8 0.0 7 6.6 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OAG09217.1 - 0.055 12.7 0.3 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 OAG09217.1 - 0.066 13.8 0.4 15 6.1 0.2 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG09217.1 - 0.069 13.5 0.0 27 5.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 OAG09217.1 - 0.08 13.0 0.3 18 5.4 0.0 2.7 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 OAG09217.1 - 0.11 11.8 0.2 2 7.7 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 OAG09217.1 - 0.12 12.3 0.9 4 7.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OAG09217.1 - 0.14 11.9 0.2 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OAG09217.1 - 0.14 11.9 0.1 14 5.4 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_5 PF07728.14 OAG09217.1 - 0.25 11.4 1.9 22 5.1 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 OAG09217.1 - 2 8.7 4.2 32 4.8 0.0 3.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NDUFA12 PF05071.16 OAG09219.1 - 3.3e-28 98.4 3.6 4.1e-28 98.1 3.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 OAG09220.1 - 3.7e-13 49.5 0.0 3.1e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAG09220.1 - 9.7e-08 31.9 3.5 0.0027 17.8 0.1 3.4 3 1 0 3 3 3 2 Phospholipase D Active site motif BAR PF03114.18 OAG09221.1 - 3.2e-50 171.0 1.1 4e-50 170.7 1.1 1.1 1 0 0 1 1 1 1 BAR domain tRNA-synt_1b PF00579.25 OAG09222.1 - 3.1e-74 249.9 0.0 4e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Diphthami_syn_2 PF01902.17 OAG09222.1 - 0.057 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Diphthamide synthase Cation_efflux PF01545.21 OAG09223.1 - 9e-23 81.0 7.1 1.1e-22 80.7 7.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG09223.1 - 4.6e-06 26.7 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pro_dh PF01619.18 OAG09224.1 - 1.9e-49 168.8 0.0 3e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase P5CR_dimer PF14748.6 OAG09224.1 - 5e-27 94.2 0.5 1.3e-26 92.9 0.5 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAG09224.1 - 8.3e-06 26.3 0.0 2.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.24 OAG09224.1 - 0.0014 18.1 0.0 0.0061 16.0 0.0 2.0 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel DAO PF01266.24 OAG09226.1 - 1.3e-35 123.6 0.0 1.5e-35 123.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG09226.1 - 2.3e-07 30.9 0.0 5.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG09226.1 - 9.5e-06 25.0 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG09226.1 - 0.00023 20.4 0.0 0.00061 19.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG09226.1 - 0.00025 20.4 0.0 0.00056 19.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG09226.1 - 0.00087 19.3 0.0 0.056 13.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG09226.1 - 0.0014 18.0 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase TrkA_N PF02254.18 OAG09226.1 - 0.002 18.4 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain HI0933_like PF03486.14 OAG09226.1 - 0.0039 15.9 0.0 0.04 12.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAG09226.1 - 0.0044 17.6 0.0 0.12 13.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG09226.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain RE_NgoBV PF09564.10 OAG09226.1 - 0.04 13.4 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 NgoBV restriction endonuclease GIDA PF01134.22 OAG09226.1 - 0.042 12.9 0.1 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 OAG09226.1 - 0.067 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 OAG09226.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 OAG09226.1 - 0.085 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.18 OAG09227.1 - 4.4e-14 52.2 0.1 1.2e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09227.1 - 9.7e-09 35.2 11.6 1.7e-08 34.4 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 OAG09228.1 - 1.5e-71 241.5 0.0 1.7e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Strep_SA_rep PF06696.11 OAG09228.1 - 0.12 12.4 1.3 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AA_permease PF00324.21 OAG09229.1 - 1.5e-102 343.7 31.4 1.7e-102 343.5 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG09229.1 - 2.3e-23 82.7 33.7 3e-23 82.4 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease DHDPS PF00701.22 OAG09230.1 - 1e-40 139.3 0.0 1.2e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_10 PF13374.6 OAG09230.1 - 0.078 12.9 1.2 0.43 10.5 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Aldedh PF00171.22 OAG09231.1 - 2.3e-93 313.2 0.0 2.9e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cation_efflux PF01545.21 OAG09232.1 - 2.1e-22 79.9 12.3 2.6e-22 79.5 12.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG09232.1 - 3.2e-07 30.4 0.0 6.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Alpha_L_fucos PF01120.17 OAG09233.1 - 2e-88 297.2 3.3 2.8e-88 296.7 3.3 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OAG09233.1 - 1e-05 26.0 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 OAG09233.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Adap_comp_sub PF00928.21 OAG09235.1 - 7e-86 287.9 0.0 8.8e-86 287.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG09235.1 - 1.4e-05 25.0 0.2 2.6e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 OAG09235.1 - 0.0064 16.0 0.2 0.01 15.3 0.2 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain OPT PF03169.15 OAG09238.1 - 8.7e-172 573.0 56.8 9.9e-172 572.8 56.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein zf-C2H2_11 PF16622.5 OAG09240.1 - 0.0021 17.8 0.4 0.0057 16.4 0.4 1.7 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 OAG09240.1 - 0.0021 18.7 1.8 0.091 13.7 0.1 2.5 1 1 1 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG09240.1 - 0.013 15.9 3.6 0.034 14.6 1.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type SLC35F PF06027.12 OAG09241.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Solute carrier family 35 Chlorophyllase2 PF12740.7 OAG09242.1 - 1.5e-06 27.3 0.0 2.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 OAG09242.1 - 0.00026 19.6 0.1 0.024 13.2 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 OAG09242.1 - 0.00065 18.8 0.0 0.00091 18.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.13 OAG09242.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAP2 PF01569.21 OAG09243.1 - 6.2e-27 94.0 0.4 6.2e-27 94.0 0.4 1.7 2 1 0 2 2 2 1 PAP2 superfamily Peroxidase_2 PF01328.17 OAG09244.1 - 1.1e-44 153.3 0.0 1.4e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 MutL_C PF08676.11 OAG09245.1 - 0.16 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 MutL C terminal dimerisation domain Cu_amine_oxid PF01179.20 OAG09246.1 - 8.3e-159 528.9 0.0 1.3e-158 528.2 0.0 1.3 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAG09246.1 - 2.7e-20 72.6 0.8 1.1e-19 70.7 0.1 2.1 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAG09246.1 - 7.8e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Mito_carr PF00153.27 OAG09247.1 - 1.2e-58 195.1 1.2 7.8e-19 67.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HET PF06985.11 OAG09248.1 - 1.1e-25 90.7 0.0 1.8e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tim29 PF10171.9 OAG09248.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 CN_hydrolase PF00795.22 OAG09250.1 - 5.4e-37 127.5 0.2 6.2e-37 127.3 0.2 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_4 PF01565.23 OAG09251.1 - 4.9e-19 68.5 0.1 2.5e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAG09253.1 - 1.5e-156 521.4 0.0 1.8e-156 521.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 OAG09253.1 - 2.3e-65 220.7 0.0 4.9e-65 219.6 0.0 1.5 2 0 0 2 2 2 1 GidA associated domain FAD_oxidored PF12831.7 OAG09253.1 - 2.5e-08 33.7 2.0 5.1e-08 32.7 1.6 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG09253.1 - 1.7e-06 27.5 2.0 1.4e-05 24.4 2.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG09253.1 - 0.00016 20.9 2.1 0.00016 20.9 2.1 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG09253.1 - 0.0073 15.6 0.2 0.017 14.4 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OAG09253.1 - 0.0094 15.6 2.1 1 8.8 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG09253.1 - 0.03 14.9 0.4 0.1 13.1 0.4 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG09253.1 - 0.035 12.8 2.6 0.048 12.4 0.4 2.2 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 OAG09253.1 - 0.11 11.5 0.8 0.23 10.5 0.8 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein SSB PF00436.25 OAG09254.1 - 8.4e-14 51.5 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family WD40 PF00400.32 OAG09255.1 - 1.2e-14 54.4 12.3 0.00043 21.0 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG09255.1 - 6e-05 23.3 0.1 0.58 10.5 0.1 3.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain VID27_N PF17748.1 OAG09255.1 - 0.048 13.5 0.9 0.1 12.4 0.9 1.5 1 0 0 1 1 1 0 VID27 N-terminal region Ge1_WD40 PF16529.5 OAG09255.1 - 0.074 12.0 0.0 8.3 5.3 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short PF00106.25 OAG09256.1 - 4.9e-12 45.7 0.0 5.7e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG09256.1 - 2.5e-11 43.6 0.0 3e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG09256.1 - 4.9e-06 26.6 0.0 7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG09256.1 - 0.19 10.8 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_6 PF01341.17 OAG09257.1 - 4.2e-93 312.4 1.8 5.3e-93 312.1 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF4602 PF15375.6 OAG09258.1 - 3.1e-07 30.8 17.8 1.3e-06 28.8 17.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) His_biosynth PF00977.21 OAG09259.1 - 7e-36 123.8 0.0 8.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 OAG09259.1 - 5.3e-05 22.6 0.1 0.00027 20.3 0.1 1.9 2 0 0 2 2 2 1 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 OAG09259.1 - 0.006 16.0 0.1 0.0087 15.5 0.1 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.17 OAG09259.1 - 0.16 11.4 0.0 0.48 9.9 0.0 1.8 2 0 0 2 2 2 0 PcrB family CDP-OH_P_transf PF01066.21 OAG09260.1 - 1.4e-15 57.8 0.3 1.4e-15 57.8 0.3 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase STE PF02200.16 OAG09261.1 - 3.1e-56 188.5 0.1 4.9e-56 187.9 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 OAG09261.1 - 1.2e-11 44.3 10.0 1.7e-06 28.2 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG09261.1 - 2.7e-09 37.1 2.5 2.7e-09 37.1 2.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG09261.1 - 8.1e-08 32.5 8.1 0.00073 20.2 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG09261.1 - 6.9e-05 22.7 3.3 0.0003 20.7 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG09261.1 - 0.00078 19.7 0.1 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OAG09261.1 - 0.0073 16.6 2.8 0.014 15.7 2.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OAG09261.1 - 0.035 14.5 0.9 0.17 12.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 OAG09261.1 - 3.4 8.2 7.0 2.3 8.7 0.0 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 OAG09261.1 - 6.4 6.6 5.7 27 4.6 3.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain XPA_C PF05181.12 OAG09262.1 - 1.3e-25 89.0 1.5 2.5e-25 88.2 1.5 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 OAG09262.1 - 0.0001 22.2 0.5 0.0001 22.2 0.5 2.3 2 0 0 2 2 2 1 XPA protein N-terminal ADD_DNMT3 PF17980.1 OAG09262.1 - 0.011 15.8 0.2 0.026 14.5 0.2 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 EcsC PF12787.7 OAG09262.1 - 0.11 12.1 0.3 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 EcsC protein family GFA PF04828.14 OAG09262.1 - 0.15 12.4 0.4 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme YhfH PF14149.6 OAG09262.1 - 5.1 7.2 9.6 0.96 9.5 0.7 2.5 2 0 0 2 2 2 0 YhfH-like protein Sugar_tr PF00083.24 OAG09263.1 - 6.1e-121 404.4 14.5 1e-120 403.7 14.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09263.1 - 3.6e-18 65.6 50.3 3.9e-09 35.9 21.6 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OAG09264.1 - 7.3e-77 258.3 0.0 7.2e-36 123.9 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 OAG09264.1 - 1.1e-75 254.5 0.1 1.1e-75 254.5 0.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 OAG09264.1 - 2.7e-47 161.2 0.0 1.7e-18 66.9 0.0 3.7 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 OAG09264.1 - 7.4e-16 58.5 0.3 8.9e-15 55.0 0.1 2.8 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 OAG09264.1 - 2.3e-13 50.1 0.7 6.3e-13 48.7 0.0 2.2 3 0 0 3 3 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 OAG09264.1 - 1.6e-08 34.2 0.0 1.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAG09264.1 - 3e-05 24.1 1.6 0.0038 17.2 0.0 3.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG09264.1 - 0.0085 15.5 0.4 3.2 7.1 0.0 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OAG09264.1 - 0.026 14.0 0.0 4.2 6.8 0.0 2.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF4502 PF14950.6 OAG09264.1 - 0.039 13.4 2.0 0.046 13.2 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4502) NinG PF05766.12 OAG09264.1 - 0.14 12.1 1.3 0.41 10.5 1.3 1.8 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF1682 PF07946.14 OAG09264.1 - 0.18 11.0 10.2 0.34 10.1 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FTA2 PF13095.6 OAG09264.1 - 0.24 11.0 5.9 0.55 9.8 0.0 3.5 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 DinB PF05163.12 OAG09264.1 - 4.6 7.1 8.4 0.67 9.9 0.0 3.2 3 0 0 3 3 3 0 DinB family Cut12 PF11500.8 OAG09265.1 - 3.2e-25 88.8 16.4 5.1e-25 88.1 14.3 2.4 1 1 0 1 1 1 1 Spindle pole body formation-associated protein Exonuc_VII_L PF02601.15 OAG09265.1 - 0.086 12.4 8.0 0.2 11.2 8.0 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit NAD_binding_9 PF13454.6 OAG09265.1 - 0.11 12.5 0.5 2.9 7.9 0.1 2.4 1 1 0 2 2 2 0 FAD-NAD(P)-binding DUF2478 PF10649.9 OAG09265.1 - 0.12 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) DUF3304 PF11745.8 OAG09265.1 - 0.23 11.9 2.3 1.1 9.7 2.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) Rod-binding PF10135.9 OAG09265.1 - 0.31 11.6 2.6 37 5.0 0.0 3.3 3 0 0 3 3 3 0 Rod binding protein YkuI_C PF10388.9 OAG09265.1 - 0.31 10.8 2.4 0.64 9.8 2.4 1.4 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain Spc7 PF08317.11 OAG09265.1 - 0.57 9.0 17.0 0.96 8.3 17.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Organ_specific PF10950.8 OAG09265.1 - 0.74 10.5 4.1 0.68 10.7 2.4 1.9 2 0 0 2 2 1 0 Organ specific protein FliD_C PF07195.12 OAG09265.1 - 1.4 8.2 8.3 2.1 7.7 5.2 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Seryl_tRNA_N PF02403.22 OAG09265.1 - 1.5 9.1 14.1 2.1 8.6 12.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phlebovirus_NSM PF07246.11 OAG09265.1 - 2.1 7.7 7.3 3.4 7.0 7.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Tho2 PF11262.8 OAG09265.1 - 9.5 5.3 9.9 15 4.6 9.9 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pept_tRNA_hydro PF01195.19 OAG09266.1 - 1.1e-32 113.3 0.0 1.5e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase FAD_binding_3 PF01494.19 OAG09267.1 - 0.025 13.9 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain WAK_assoc PF14380.6 OAG09269.1 - 0.024 15.4 0.2 0.053 14.3 0.2 1.6 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal DUF4298 PF14131.6 OAG09270.1 - 0.067 13.2 1.1 0.7 9.9 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) DUF1308 PF07000.11 OAG09270.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) DUF3328 PF11807.8 OAG09271.1 - 1.3e-41 142.8 1.7 1.4e-41 142.7 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAG09272.1 - 1.7e-38 132.6 0.3 1.9e-38 132.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) YtkA PF13115.6 OAG09273.1 - 0.043 14.4 0.1 1.2 9.8 0.0 2.3 1 1 1 2 2 2 0 YtkA-like Nop16 PF09420.10 OAG09273.1 - 0.052 13.6 0.0 0.59 10.1 0.0 2.0 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF3328 PF11807.8 OAG09274.1 - 2.6e-41 141.8 1.9 2.9e-41 141.7 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Jagunal PF07086.12 OAG09275.1 - 0.071 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis Haem_degrading PF03928.14 OAG09276.1 - 1.2e-27 96.3 0.0 1.4e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading DUF3035 PF11233.8 OAG09277.1 - 0.23 11.7 1.3 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) MS_channel PF00924.18 OAG09281.1 - 3.1e-20 72.6 0.5 5.7e-20 71.7 0.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_8 PF13833.6 OAG09281.1 - 0.025 14.4 0.6 0.064 13.1 0.6 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 OAG09281.1 - 0.05 13.2 1.2 0.12 12.0 1.2 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OAG09281.1 - 0.11 12.5 1.1 0.33 11.0 1.1 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 OAG09281.1 - 0.13 12.8 0.5 0.35 11.4 0.5 1.7 1 0 0 1 1 1 0 EF-hand domain pair Frag1 PF10277.9 OAG09282.1 - 5.3e-17 62.1 9.1 5.3e-17 62.1 9.1 1.6 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family TMEM125 PF15109.6 OAG09283.1 - 0.43 10.9 6.0 0.76 10.1 6.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family DUF202 PF02656.15 OAG09283.1 - 1.3 9.5 5.0 5.5 7.5 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Peroxidase_2 PF01328.17 OAG09284.1 - 1.2e-51 175.9 0.1 1.5e-51 175.6 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF1325 PF07039.11 OAG09284.1 - 0.017 15.2 0.2 0.027 14.6 0.2 1.2 1 0 0 1 1 1 0 SGF29 tudor-like domain Pro_CA PF00484.19 OAG09285.1 - 1.4e-11 44.9 0.7 2.3e-10 41.0 0.7 2.0 1 1 0 1 1 1 1 Carbonic anhydrase F-box-like PF12937.7 OAG09286.1 - 3.2e-05 23.7 0.0 0.0001 22.1 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 OAG09286.1 - 0.04 13.8 2.2 0.084 12.8 0.1 2.7 2 1 0 2 2 2 0 F-box domain Rnk_N PF14760.6 OAG09286.1 - 0.18 12.3 2.2 0.71 10.4 2.2 2.0 1 0 0 1 1 1 0 Rnk N-terminus Abhydrolase_3 PF07859.13 OAG09287.1 - 4e-52 177.1 0.0 5.3e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG09287.1 - 1.4e-05 24.2 0.2 5.8e-05 22.2 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG09287.1 - 0.00048 19.7 0.0 0.0087 15.6 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG09287.1 - 0.037 14.6 0.0 0.059 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short_C2 PF13561.6 OAG09288.1 - 5.8e-59 199.5 1.8 7e-59 199.2 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG09288.1 - 8.1e-45 152.7 3.2 1e-44 152.4 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Ntox4 PF15541.6 OAG09288.1 - 0.05 14.0 0.2 0.45 10.9 0.1 2.3 2 1 1 3 3 3 0 Bacterial toxin 4 Response_reg PF00072.24 OAG09289.1 - 4.7e-23 81.5 0.0 1e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG09289.1 - 9.9e-23 80.8 0.2 9.9e-23 80.8 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG09289.1 - 2.3e-13 50.0 0.0 6.3e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OAG09289.1 - 0.069 13.0 0.4 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 OAG09289.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 GHKL domain LigB PF02900.18 OAG09290.1 - 7.2e-32 110.5 0.1 1.4e-31 109.6 0.1 1.4 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MMR_HSR1 PF01926.23 OAG09291.1 - 3.9e-17 62.4 0.2 2.8e-15 56.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG09291.1 - 1e-07 31.6 0.5 6.9e-06 25.7 0.1 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG09291.1 - 3.6e-05 23.7 0.1 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OAG09291.1 - 0.0047 17.0 4.4 0.14 12.2 0.1 3.5 3 0 0 3 3 3 1 Dynamin family AIG1 PF04548.16 OAG09291.1 - 0.016 14.6 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 OAG09291.1 - 1.9 9.0 4.7 7.6 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain LTV PF04180.14 OAG09292.1 - 1.3e-119 400.4 15.4 1.5e-119 400.2 15.4 1.0 1 0 0 1 1 1 1 Low temperature viability protein Sybindin PF04099.12 OAG09293.1 - 7.7e-25 87.5 0.0 9.6e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAG09293.1 - 0.037 14.1 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.25 OAG09294.1 - 1.9e-62 211.0 0.0 4.7e-56 190.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG09294.1 - 4.9e-38 130.9 0.1 3.1e-36 125.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG09294.1 - 2e-07 30.6 0.0 4.6e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAG09294.1 - 2.4e-05 23.3 0.3 6e-05 22.0 0.3 1.8 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG09294.1 - 0.0025 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAG09294.1 - 0.11 12.1 0.0 0.94 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3340 PF11818.8 OAG09294.1 - 0.16 12.2 5.1 6.3 6.9 0.0 2.7 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Pkinase PF00069.25 OAG09297.1 - 1.8e-50 171.7 0.0 2.8e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG09297.1 - 3.2e-29 102.0 0.0 5e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG09297.1 - 0.0017 17.8 0.1 0.0053 16.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OAG09297.1 - 0.0028 17.1 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GET2 PF08690.10 OAG09297.1 - 0.035 13.8 1.5 0.052 13.2 1.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 APH PF01636.23 OAG09297.1 - 0.062 13.2 0.3 1.1 9.1 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG09297.1 - 0.13 11.8 0.2 0.72 9.4 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sad1_UNC PF07738.13 OAG09298.1 - 4.5e-32 110.8 0.0 7.1e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Acyl-CoA_dh_1 PF00441.24 OAG09299.1 - 1.6e-27 96.5 0.2 2.7e-27 95.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG09299.1 - 1.1e-20 73.6 0.0 2.4e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG09299.1 - 8.3e-17 61.9 0.1 3.2e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG09299.1 - 1.3e-10 41.7 0.7 2.3e-10 40.9 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CAP59_mtransfer PF11735.8 OAG09301.1 - 3.9e-88 295.2 0.0 4.8e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 F-box-like PF12937.7 OAG09302.1 - 0.037 13.9 0.7 0.14 12.0 0.7 2.0 1 1 0 1 1 1 0 F-box-like DASH_Dad1 PF08649.10 OAG09303.1 - 0.046 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad1 Peroxin-3 PF04882.12 OAG09304.1 - 1.9e-169 564.6 3.0 2.2e-169 564.4 3.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DGCR6 PF07324.11 OAG09304.1 - 0.1 12.2 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Glyco_transf_8 PF01501.20 OAG09305.1 - 2.9e-09 36.9 0.3 5.9e-09 35.9 0.3 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 OAG09305.1 - 0.012 15.6 1.0 0.031 14.2 1.0 1.6 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase bZIP_1 PF00170.21 OAG09306.1 - 2.2e-06 27.6 7.3 2.2e-06 27.6 7.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAG09306.1 - 0.001 19.1 9.0 0.0023 18.0 9.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper LURAP PF14854.6 OAG09306.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Leucine rich adaptor protein Oberon_cc PF16312.5 OAG09306.1 - 0.037 14.0 1.9 0.037 14.0 1.9 1.7 2 0 0 2 2 2 0 Coiled-coil region of Oberon GCN5L1 PF06320.13 OAG09306.1 - 0.087 13.0 4.7 0.18 12.0 4.7 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF4407 PF14362.6 OAG09306.1 - 0.16 11.3 2.0 0.26 10.6 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FTA4 PF13093.6 OAG09306.1 - 2 8.3 7.5 1.6 8.6 4.1 2.2 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DivIC PF04977.15 OAG09306.1 - 2.5 7.9 5.2 0.97 9.3 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator Pec_lyase_C PF00544.19 OAG09308.1 - 2.4e-37 128.6 8.2 3.3e-37 128.1 8.2 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG09308.1 - 1.2e-05 25.2 10.4 0.001 19.0 0.7 2.3 1 1 1 2 2 2 2 Right handed beta helix region fn3_3 PF14686.6 OAG09310.1 - 2.3e-27 94.6 0.9 5.5e-27 93.3 0.9 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 OAG09310.1 - 1.3e-23 83.7 0.1 2.1e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 OAG09310.1 - 0.013 15.7 0.1 0.036 14.3 0.1 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Ank_4 PF13637.6 OAG09312.1 - 3.8e-16 59.2 0.0 9.2e-11 42.1 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG09312.1 - 5e-12 46.2 0.0 5.3e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG09312.1 - 1.2e-10 41.3 0.0 1.9e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OAG09312.1 - 1.8e-10 40.1 0.0 5.8e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OAG09312.1 - 9.5e-07 29.0 0.0 4e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG09313.1 - 7e-20 71.4 0.0 1.6e-10 41.5 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG09313.1 - 3e-17 62.7 0.0 7.7e-10 39.1 0.0 3.7 2 1 2 4 4 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG09313.1 - 2.6e-15 56.1 0.1 0.00017 21.9 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 OAG09313.1 - 5.3e-15 54.0 0.1 0.0037 17.7 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat NACHT PF05729.12 OAG09313.1 - 5.5e-09 36.2 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 OAG09313.1 - 1.6e-08 34.7 0.0 3e-06 27.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 OAG09313.1 - 0.0043 17.5 1.4 0.013 15.9 0.1 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG09313.1 - 0.016 15.5 0.0 0.061 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain GATA PF00320.27 OAG09313.1 - 0.044 13.4 0.2 15 5.3 0.0 2.5 2 0 0 2 2 2 0 GATA zinc finger RRM_Rrp7 PF17799.1 OAG09313.1 - 0.056 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain KAP_NTPase PF07693.14 OAG09313.1 - 0.13 11.5 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain Prenylcys_lyase PF07156.14 OAG09313.1 - 0.13 11.3 0.5 6 5.9 0.0 2.7 3 0 0 3 3 3 0 Prenylcysteine lyase RBM39linker PF15519.6 OAG09314.1 - 0.0033 18.5 0.0 0.0046 18.0 0.0 1.2 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein SrfB PF07520.11 OAG09317.1 - 0.18 9.7 0.0 0.22 9.3 0.0 1.0 1 0 0 1 1 1 0 Virulence factor SrfB Pkinase PF00069.25 OAG09318.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 OAG09318.1 - 0.096 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3435 PF11917.8 OAG09319.1 - 1.4e-05 24.3 1.1 7.6e-05 21.8 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) zf-H2C2_2 PF13465.6 OAG09319.1 - 0.028 14.8 10.1 0.14 12.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf_C2H2_10 PF18414.1 OAG09319.1 - 6.1 6.5 5.5 5.8 6.5 0.6 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C2H2_11 PF16622.5 OAG09319.1 - 6.9 6.5 7.5 2.1 8.2 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type CVNH PF08881.10 OAG09320.1 - 9.3e-12 45.5 0.3 3.2e-11 43.8 0.3 1.9 1 0 0 1 1 1 1 CVNH domain Ank_3 PF13606.6 OAG09321.1 - 3.9e-17 60.6 0.1 1 10.2 0.0 7.1 6 1 1 7 7 7 6 Ankyrin repeat Ank_2 PF12796.7 OAG09321.1 - 2.2e-14 53.8 0.0 0.00014 22.4 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG09321.1 - 5.5e-14 52.3 0.0 0.00043 20.8 0.0 5.4 4 2 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG09321.1 - 1.1e-10 41.6 0.1 0.64 10.4 0.0 5.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG09321.1 - 1.6e-07 31.5 0.0 2.2 8.9 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat CHAT PF12770.7 OAG09323.1 - 6.7e-39 134.0 0.2 1.2e-38 133.2 0.2 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 OAG09323.1 - 2.5e-35 119.4 34.8 0.0004 20.2 0.1 15.3 15 1 0 15 15 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 OAG09323.1 - 2.3e-14 52.3 2.8 1.8 9.0 0.0 11.2 11 1 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG09323.1 - 3.4e-13 49.7 22.7 0.37 11.1 0.1 12.1 8 3 4 12 12 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG09323.1 - 3.5e-13 48.6 3.5 0.2 11.9 0.0 10.8 11 1 0 11 11 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG09323.1 - 8.9e-12 44.8 15.5 4.6 8.3 0.1 12.1 12 0 0 12 12 11 1 Tetratricopeptide repeat DUF4404 PF14357.6 OAG09323.1 - 4.6e-09 36.8 10.7 0.37 11.4 0.1 7.2 7 0 0 7 7 6 2 Domain of unknown function (DUF4404) RPN6_N PF18055.1 OAG09323.1 - 2e-06 28.2 4.5 1.2 9.6 0.0 7.6 7 2 3 10 10 10 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_1 PF00515.28 OAG09323.1 - 6.9e-05 22.5 4.7 1 9.3 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat CENP-Q PF13094.6 OAG09323.1 - 0.00024 21.3 14.1 14 5.9 0.0 7.7 3 1 2 5 5 5 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_16 PF13432.6 OAG09323.1 - 0.00037 21.1 5.5 6.9 7.4 0.0 7.0 6 1 2 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG09323.1 - 0.0014 18.3 10.0 4.7 7.0 0.0 7.4 9 0 0 9 9 8 1 TPR repeat CODH_A_N PF18537.1 OAG09323.1 - 0.018 15.1 2.8 0.97 9.5 0.0 5.4 6 1 1 7 7 6 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain HGD-D PF06050.13 OAG09323.1 - 0.022 14.5 2.7 5.7 6.6 0.0 3.8 1 1 1 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component VWA_2 PF13519.6 OAG09323.1 - 0.022 15.4 10.8 1.2e+02 3.3 0.0 8.1 5 1 4 10 10 9 0 von Willebrand factor type A domain CENP-O PF09496.10 OAG09323.1 - 0.025 14.6 7.3 2.5 8.0 0.2 5.2 2 2 3 5 5 5 0 Cenp-O kinetochore centromere component AbiEi_3_N PF17194.4 OAG09323.1 - 0.025 14.6 0.1 0.9 9.6 0.0 3.6 2 1 0 3 3 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain DELLA PF12041.8 OAG09323.1 - 0.04 13.8 3.5 0.92 9.5 0.0 4.7 6 0 0 6 6 3 0 Transcriptional regulator DELLA protein N terminal ATP-synt_ab PF00006.25 OAG09323.1 - 0.17 11.5 0.0 6 6.5 0.0 3.3 2 1 2 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain Laminin_II PF06009.12 OAG09323.1 - 0.27 11.2 8.6 34 4.4 0.4 5.0 3 1 4 7 7 6 0 Laminin Domain II TPR_19 PF14559.6 OAG09323.1 - 3.2 8.3 17.0 8.9 6.9 0.1 7.7 9 1 0 9 9 5 0 Tetratricopeptide repeat Jag_N PF14804.6 OAG09323.1 - 4.8 7.6 9.2 25 5.3 0.0 6.2 8 0 0 8 8 6 0 Jag N-terminus DUF4164 PF13747.6 OAG09323.1 - 7.9 6.8 16.0 34 4.8 0.2 6.5 6 0 0 6 6 5 0 Domain of unknown function (DUF4164) FTA4 PF13093.6 OAG09323.1 - 8.4 6.2 7.2 3.1e+03 -2.2 7.2 4.1 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fungal_trans_2 PF11951.8 OAG09324.1 - 1.4e-07 30.6 0.9 2.3e-07 30.0 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PatG_D PF18047.1 OAG09327.1 - 0.0075 16.7 0.1 0.019 15.4 0.1 1.7 1 0 0 1 1 1 1 PatG Domain zf-met2 PF12907.7 OAG09328.1 - 0.055 13.6 2.9 0.091 12.9 2.9 1.4 1 0 0 1 1 1 0 Zinc-binding Gin PF10764.9 OAG09328.1 - 0.072 13.1 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin TPR_10 PF13374.6 OAG09331.1 - 2.9e-39 131.9 6.7 3.9e-10 39.3 0.4 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAG09331.1 - 1.4e-38 131.0 7.6 1.4e-15 57.3 0.7 4.5 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG09331.1 - 1.8e-19 68.7 6.5 1.8e-05 24.3 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG09331.1 - 4.4e-16 57.6 4.3 0.00034 20.5 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAG09331.1 - 5.8e-16 57.3 7.7 0.00026 20.8 0.2 5.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG09331.1 - 7.3e-09 35.2 4.0 0.94 9.9 0.0 5.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG09331.1 - 3.6e-07 30.7 7.8 0.32 11.7 0.1 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG09331.1 - 2.5e-05 23.6 0.0 6.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_4 PF07721.14 OAG09331.1 - 0.00025 21.4 2.6 0.87 10.4 0.1 4.9 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 OAG09331.1 - 0.00029 21.3 2.6 0.0003 21.2 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain TPR_6 PF13174.6 OAG09331.1 - 0.00031 21.2 2.3 7.3 7.5 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG09331.1 - 0.00088 19.9 13.9 3.2 8.8 0.1 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG09331.1 - 0.001 18.6 16.4 0.0044 16.4 0.2 3.7 3 1 1 4 4 4 2 MalT-like TPR region TPR_3 PF07720.12 OAG09331.1 - 0.0012 18.8 0.7 2.2 8.3 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG09331.1 - 0.0024 18.3 7.0 14 6.3 0.1 5.2 4 1 2 6 6 6 0 Tetratricopeptide repeat APS_kinase PF01583.20 OAG09331.1 - 0.0031 17.4 0.1 0.11 12.4 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 OAG09331.1 - 0.015 14.9 0.2 0.054 13.1 0.2 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG09331.1 - 0.057 13.4 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG09331.1 - 0.074 13.3 0.0 0.29 11.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain TPR_17 PF13431.6 OAG09331.1 - 0.24 11.8 8.7 38 5.0 0.0 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG09331.1 - 0.32 10.7 3.6 10 5.9 0.1 3.8 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 OAG09331.1 - 0.71 10.1 4.1 15 5.8 0.5 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat DSBA PF01323.20 OAG09332.1 - 2.1e-17 63.5 0.0 2.4e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Beta_elim_lyase PF01212.21 OAG09332.1 - 0.032 13.5 0.0 0.038 13.3 0.0 1.3 1 1 0 1 1 1 0 Beta-eliminating lyase Thioredoxin_4 PF13462.6 OAG09332.1 - 0.034 14.3 0.0 0.26 11.4 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_14 PF18402.1 OAG09332.1 - 0.17 11.9 0.0 2.7 7.9 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain CAP PF00188.26 OAG09333.1 - 7e-15 56.0 1.9 1e-14 55.4 1.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase PF00069.25 OAG09334.1 - 4.1e-64 216.5 0.0 5.1e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG09334.1 - 1.8e-30 106.1 0.0 2.8e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG09334.1 - 0.00014 20.9 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG09334.1 - 0.027 14.4 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2748 PF10871.8 OAG09334.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) CBF PF03914.17 OAG09334.1 - 0.15 12.1 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 CBF/Mak21 family Sugar_tr PF00083.24 OAG09335.1 - 1.9e-94 317.1 5.4 2.7e-94 316.6 5.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter GTP_cyclohydro2 PF00925.20 OAG09335.1 - 1.7e-56 190.3 0.0 3.1e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II MFS_1 PF07690.16 OAG09335.1 - 5.9e-30 104.4 50.4 1.7e-27 96.3 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG09335.1 - 0.00079 18.0 1.6 0.00079 18.0 1.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG09335.1 - 0.6 8.3 10.6 0.58 8.4 0.0 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SCAB-Ig PF16709.5 OAG09336.1 - 0.026 14.6 0.1 4.6 7.4 0.0 2.6 1 1 0 2 2 2 0 Ig domain of plant-specific actin-binding protein COesterase PF00135.28 OAG09337.1 - 7e-81 272.6 0.0 9.8e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG09337.1 - 1.4e-05 25.1 0.1 0.0002 21.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DNA_ligase_A_N PF04675.14 OAG09338.1 - 9.3e-45 153.0 0.0 1.6e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 OAG09338.1 - 9.8e-43 146.2 0.0 2.1e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 OAG09338.1 - 6e-15 55.9 0.0 1.2e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 OAG09338.1 - 1.5e-14 54.1 0.0 2.5e-11 43.8 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 OAG09338.1 - 2e-13 50.8 0.0 5.5e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region LIG3_BRCT PF16759.5 OAG09338.1 - 2.1e-09 37.5 0.2 0.002 18.4 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 OAG09338.1 - 9.5e-09 35.5 0.0 9.4e-08 32.3 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Bac_globin PF01152.21 OAG09338.1 - 0.024 14.8 0.0 0.073 13.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial-like globin EF-hand_4 PF12763.7 OAG09339.1 - 0.00013 21.9 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Peptidase_S26 PF10502.9 OAG09340.1 - 8.4e-08 32.1 0.0 3e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OAG09340.1 - 1.8e-06 27.8 0.2 2.1e-05 24.4 0.1 2.3 1 1 1 2 2 2 1 Peptidase S24-like Cupin_8 PF13621.6 OAG09341.1 - 3.7e-62 210.3 0.1 4.8e-62 210.0 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAG09341.1 - 6.1e-06 25.9 0.0 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Peptidase_M35 PF02102.15 OAG09343.1 - 1.5e-96 323.4 22.4 1.7e-96 323.2 22.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 OAG09343.1 - 1.8e-39 135.6 7.9 1.8e-39 135.6 7.9 2.0 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase DUF676 PF05057.14 OAG09345.1 - 2.6e-52 177.5 0.0 4.5e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG09345.1 - 2.1e-06 28.5 0.0 4.1e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAG09345.1 - 9.9e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 OAG09345.1 - 0.002 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 OAG09345.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein PE-PPE PF08237.11 OAG09345.1 - 0.018 14.6 0.0 0.053 13.1 0.0 1.7 2 0 0 2 2 2 0 PE-PPE domain Phlebovirus_G2 PF07245.11 OAG09345.1 - 0.042 12.4 0.1 0.064 11.7 0.1 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Lipase_2 PF01674.18 OAG09345.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) RNase_T PF00929.24 OAG09346.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.7 1 0 0 1 1 1 0 Exonuclease DUF3431 PF11913.8 OAG09347.1 - 3e-85 285.4 0.2 3.9e-85 285.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) F-box PF00646.33 OAG09348.1 - 1.9e-05 24.4 0.2 9.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG09348.1 - 0.00012 21.9 0.0 0.00046 20.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like Polysacc_lyase PF14099.6 OAG09348.1 - 0.0011 18.9 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase Tudor_2 PF18104.1 OAG09348.1 - 0.27 11.0 2.3 6.8 6.5 0.2 2.8 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain KTI12 PF08433.10 OAG09350.1 - 2.1e-88 296.3 0.0 2.4e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 OAG09350.1 - 0.025 14.9 0.0 0.065 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 OAG09350.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 OAG09350.1 - 0.096 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG09350.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.18 OAG09352.1 - 1.4e-33 116.1 0.1 1.4e-33 116.1 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09352.1 - 9.6e-10 38.4 11.1 1.7e-09 37.6 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mod_r PF07200.13 OAG09352.1 - 0.081 13.0 0.2 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 OAG09352.1 - 0.093 12.8 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor Trimer_CC PF08954.11 OAG09352.1 - 5.9 6.5 5.8 0.8 9.3 1.1 2.0 2 0 0 2 2 2 0 Trimerisation motif SET PF00856.28 OAG09353.1 - 1e-06 29.3 0.0 1.8e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 SET domain DSPn PF14671.6 OAG09354.1 - 1.4e-41 142.2 0.0 3.8e-39 134.3 0.0 2.6 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OAG09354.1 - 3.1e-16 59.4 0.0 5.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG09354.1 - 8.7e-06 25.5 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG09354.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Dynamin_N PF00350.23 OAG09355.1 - 3.5e-16 59.7 0.9 1.2e-15 58.0 0.0 2.4 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OAG09355.1 - 1.3e-09 38.1 0.0 4e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-RING_2 PF13639.6 OAG09355.1 - 1.5e-07 31.6 1.6 1.5e-07 31.6 1.6 2.3 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 OAG09355.1 - 5.7e-07 29.7 0.4 1.3e-06 28.6 0.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG09355.1 - 4e-06 26.6 0.2 7.6e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG09355.1 - 1.1e-05 25.2 0.3 2.7e-05 24.0 0.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain GTP_EFTU PF00009.27 OAG09355.1 - 1.7e-05 24.4 0.0 0.0035 16.9 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain zf-C3HC4_2 PF13923.6 OAG09355.1 - 4e-05 23.4 1.5 4e-05 23.4 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG09355.1 - 0.00054 19.5 0.3 0.0012 18.4 0.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAG09355.1 - 0.00055 19.9 0.1 0.0017 18.3 0.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger DUF2921 PF11145.8 OAG09355.1 - 0.00082 17.3 0.4 0.023 12.5 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2921) zf-RING_11 PF17123.5 OAG09355.1 - 0.0023 17.6 3.6 0.0073 16.0 0.2 2.4 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 OAG09355.1 - 0.0028 17.5 0.9 0.0069 16.2 0.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2205 PF10224.9 OAG09355.1 - 0.0091 16.0 0.9 0.027 14.5 0.9 1.7 1 0 0 1 1 1 1 Short coiled-coil protein IIGP PF05049.13 OAG09355.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 OAG09355.1 - 0.074 13.0 1.0 8 6.3 0.1 2.9 3 1 0 3 3 3 0 RsgA GTPase zf-C3HC4_3 PF13920.6 OAG09355.1 - 0.074 12.9 4.9 0.017 15.0 1.4 1.7 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) cobW PF02492.19 OAG09355.1 - 0.12 11.9 0.6 0.79 9.3 0.6 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain zf-ANAPC11 PF12861.7 OAG09355.1 - 0.14 12.3 0.9 0.31 11.1 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pex14_N PF04695.13 OAG09355.1 - 2.5 8.8 10.7 8.2 7.1 10.7 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C3H2C3 PF17122.5 OAG09355.1 - 4.3 7.4 4.6 11 6.2 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger Snf7 PF03357.21 OAG09356.1 - 5e-36 123.9 25.6 5e-36 123.9 25.6 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 OAG09356.1 - 0.41 10.6 8.6 0.77 9.7 8.5 1.6 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway O-antigen_lig PF13425.6 OAG09356.1 - 2 7.1 6.4 2.4 6.8 6.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Exonuc_VII_L PF02601.15 OAG09356.1 - 4.3 6.8 13.5 3.2 7.2 11.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit PP2C PF00481.21 OAG09357.1 - 9.1e-62 209.0 0.3 7e-50 170.1 0.5 2.9 1 1 1 2 2 2 2 Protein phosphatase 2C CBS PF00571.28 OAG09358.1 - 7.3e-22 77.6 9.1 8.6e-09 35.7 0.1 4.3 4 0 0 4 4 4 3 CBS domain HTH_9 PF08221.11 OAG09358.1 - 0.14 12.3 2.1 3.5 7.8 0.0 3.7 5 0 0 5 5 5 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Rhomboid PF01694.22 OAG09359.1 - 8.8e-38 129.7 5.1 8.8e-38 129.7 5.1 2.1 2 0 0 2 2 2 1 Rhomboid family DUF3792 PF12670.7 OAG09359.1 - 5.6 7.2 15.5 0.68 10.1 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Wzy_C PF04932.15 OAG09359.1 - 8.8 5.9 8.9 0.7 9.5 0.5 2.9 3 1 0 3 3 3 0 O-Antigen ligase zf-C2H2 PF00096.26 OAG09360.1 - 1.1e-11 44.5 19.1 0.0094 16.4 0.2 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG09360.1 - 1.5e-11 44.1 22.5 0.011 16.6 0.3 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OAG09360.1 - 0.00045 20.5 11.4 0.017 15.4 0.8 3.7 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 OAG09360.1 - 0.00088 19.2 20.4 0.43 10.6 2.1 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG09360.1 - 0.019 14.7 0.2 0.019 14.7 0.2 3.7 5 0 0 5 5 4 0 zinc-finger C2H2-type zf-Di19 PF05605.12 OAG09360.1 - 0.12 12.6 29.0 0.17 12.2 2.6 5.1 3 2 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 OAG09360.1 - 0.13 12.6 17.2 4.7 7.6 1.9 4.7 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OAG09360.1 - 0.19 12.2 7.8 4.6 7.8 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OAG09360.1 - 0.63 10.0 4.5 3.6 7.6 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 OAG09360.1 - 1.8 8.5 10.2 7.5 6.5 0.0 4.2 2 2 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 OAG09360.1 - 2 8.5 10.1 0.83 9.7 0.5 3.4 2 1 1 3 3 3 0 BED zinc finger FYVE PF01363.21 OAG09360.1 - 6.4 7.0 16.4 0.65 10.2 3.6 3.8 3 1 0 3 3 3 0 FYVE zinc finger Cyanate_lyase PF02560.14 OAG09361.1 - 8.1e-33 112.1 0.0 1.2e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_19 PF12844.7 OAG09361.1 - 1.1e-05 25.4 0.1 2.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 OAG09361.1 - 0.00039 20.4 0.1 0.00057 19.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_38 PF13936.6 OAG09361.1 - 0.086 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 OAG09361.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 PLDc_2 PF13091.6 OAG09362.1 - 3.3e-16 59.4 0.0 2.9e-06 27.2 0.0 4.4 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAG09362.1 - 1.6e-12 47.0 0.3 1.1e-05 25.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif HAD_2 PF13419.6 OAG09366.1 - 0.026 14.6 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG09366.1 - 0.058 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.26 OAG09366.1 - 0.13 12.5 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2014 PF09427.10 OAG09367.1 - 3.2e-104 348.0 0.7 4.7e-104 347.4 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 OAG09367.1 - 2.3e-17 62.7 0.0 1.1e-16 60.5 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAP1 PF08601.10 OAG09367.1 - 0.17 11.6 9.2 0.3 10.8 9.2 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 GIT_CC PF16559.5 OAG09367.1 - 0.21 11.5 0.2 0.94 9.4 0.1 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ATG16 PF08614.11 OAG09367.1 - 0.99 9.6 6.0 4.9 7.3 0.2 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HET PF06985.11 OAG09369.1 - 3.8e-25 88.9 0.0 7.9e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF488 PF04343.13 OAG09369.1 - 0.038 14.6 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF488 Methyltransf_31 PF13847.6 OAG09370.1 - 1.2e-27 96.5 0.0 1.9e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG09370.1 - 3.4e-24 85.3 0.0 7e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG09370.1 - 2e-23 82.9 0.0 4.3e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG09370.1 - 5.7e-16 59.1 0.0 8.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG09370.1 - 9.6e-15 54.5 0.0 1.4e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG09370.1 - 7.5e-10 38.9 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG09370.1 - 4.8e-08 32.7 0.0 1.1e-07 31.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase small domain MetW PF07021.12 OAG09370.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 OAG09370.1 - 2.2e-05 24.0 0.0 0.032 13.7 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 OAG09370.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 OAG09370.1 - 0.00018 21.3 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 OAG09370.1 - 0.00032 20.4 0.0 0.0052 16.5 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 OAG09370.1 - 0.00057 19.4 0.0 0.00094 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 OAG09370.1 - 0.00065 19.2 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OAG09370.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 OAG09370.1 - 0.0033 17.2 0.0 0.0071 16.0 0.0 1.5 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 OAG09370.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_8 PF05148.15 OAG09370.1 - 0.038 13.8 0.0 0.099 12.5 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase FtsJ PF01728.19 OAG09370.1 - 0.055 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 OAG09370.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 OAG09370.1 - 0.19 10.2 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase BRCT PF00533.26 OAG09371.1 - 5.6e-05 23.4 0.1 0.0001 22.6 0.1 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG09371.1 - 0.0098 16.3 0.2 0.018 15.4 0.2 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 OAG09371.1 - 0.058 13.3 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 twin BRCT domain Homeodomain PF00046.29 OAG09372.1 - 3.9e-14 52.2 3.7 1e-13 50.9 3.7 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG09372.1 - 0.1 12.5 0.7 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Homeobox KN domain NmrA PF05368.13 OAG09373.1 - 9.8e-06 25.3 0.0 3.3e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG09373.1 - 2.9e-05 24.1 0.1 0.00023 21.1 0.0 2.3 3 0 0 3 3 3 1 NAD(P)H-binding GPI-anchored PF10342.9 OAG09373.1 - 0.072 13.9 0.0 0.87 10.4 0.0 2.4 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KR PF08659.10 OAG09373.1 - 0.078 12.9 0.9 0.24 11.3 0.0 2.2 3 0 0 3 3 3 0 KR domain GP40 PF11025.8 OAG09374.1 - 0.05 13.4 0.8 0.063 13.0 0.8 1.2 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium IGPS PF00218.21 OAG09376.1 - 2.6e-97 325.0 0.0 5.4e-97 323.9 0.0 1.5 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 OAG09376.1 - 1.4e-50 171.8 0.2 4e-45 154.0 0.1 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 OAG09376.1 - 9.2e-46 156.0 0.0 1.7e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NanE PF04131.14 OAG09376.1 - 5.8e-05 22.4 0.1 0.11 11.7 0.0 3.0 3 0 0 3 3 3 2 Putative N-acetylmannosamine-6-phosphate epimerase Peptidase_C26 PF07722.13 OAG09376.1 - 0.00053 19.8 1.1 0.0019 18.0 1.1 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 OAG09376.1 - 0.0052 16.6 2.0 0.21 11.4 0.1 3.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 OAG09376.1 - 0.097 12.1 0.2 1.6 8.2 0.0 2.7 3 0 0 3 3 3 0 Histidine biosynthesis protein Nup188_C PF18378.1 OAG09377.1 - 4.1e-114 381.3 0.0 7.5e-114 380.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 OAG09377.1 - 2.8e-48 164.6 0.0 8.2e-46 156.4 0.0 3.4 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 MFS_1 PF07690.16 OAG09378.1 - 1.6e-41 142.4 51.9 1.6e-41 142.4 51.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 OAG09379.1 - 3.5e-34 118.3 0.0 4.6e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09379.1 - 2.1e-07 31.0 10.3 3.8e-07 30.1 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.14 OAG09380.1 - 7.3e-44 150.8 12.5 7.3e-44 150.8 12.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG09380.1 - 5.9e-07 28.9 1.9 0.0037 16.4 0.0 3.1 1 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 LANC_like PF05147.13 OAG09380.1 - 0.0061 15.2 0.0 1.3 7.5 0.0 2.4 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 OAG09380.1 - 0.011 15.2 2.5 0.1 12.1 1.1 2.8 3 1 1 4 4 4 0 D-glucuronyl C5-epimerase C-terminus DUF1993 PF09351.10 OAG09381.1 - 5.4e-36 124.2 0.0 6.3e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Mo-nitro_C PF06967.11 OAG09381.1 - 0.19 11.7 0.1 0.65 10.0 0.1 2.0 1 1 0 1 1 1 0 Mo-dependent nitrogenase C-terminus AMP-binding PF00501.28 OAG09382.1 - 2.3e-21 75.9 0.1 2.8e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme FAD_binding_4 PF01565.23 OAG09385.1 - 7.1e-27 93.8 0.0 1.1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG09385.1 - 3.2e-11 43.4 0.0 5.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_3 PF01494.19 OAG09386.1 - 1.9e-17 63.6 0.1 1.8e-11 43.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG09386.1 - 3.8e-09 36.2 1.0 0.00053 19.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG09386.1 - 4.8e-07 29.7 5.7 0.0013 18.4 0.0 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG09386.1 - 1.7e-06 27.4 1.3 1.7e-05 24.1 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG09386.1 - 0.00021 20.1 0.2 0.37 9.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 OAG09386.1 - 0.00042 20.5 0.4 0.0012 19.0 0.4 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG09386.1 - 0.00064 18.9 3.9 0.004 16.3 3.9 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAG09386.1 - 0.002 18.7 0.3 0.36 11.4 0.1 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG09386.1 - 0.023 14.0 0.7 0.17 11.2 0.4 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG09386.1 - 0.035 14.1 1.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAG09386.1 - 0.074 11.9 0.3 0.71 8.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG09386.1 - 0.11 11.7 0.1 0.52 9.5 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 OAG09389.1 - 9.3e-16 58.9 2.0 1.7e-15 58.0 2.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG09389.1 - 0.082 13.1 0.0 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Aa_trans PF01490.18 OAG09390.1 - 5.8e-29 101.0 19.9 8.1e-29 100.5 19.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pox_A14 PF05767.12 OAG09390.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.8 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Viral_Beta_CD PF04530.12 OAG09391.1 - 0.073 13.4 0.2 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Viral Beta C/D like family Peptidase_C101 PF16218.5 OAG09395.1 - 0.019 14.3 0.2 0.029 13.6 0.0 1.4 2 0 0 2 2 2 0 Peptidase family C101 Sugar_tr PF00083.24 OAG09398.1 - 2.3e-57 194.8 12.7 2.7e-57 194.6 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09398.1 - 2.5e-17 62.8 29.6 2.4e-16 59.6 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG09398.1 - 1.8e-07 30.1 17.1 2.9e-05 22.8 4.0 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein DUF4131 PF13567.6 OAG09398.1 - 3 7.5 9.1 0.1 12.2 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_25 PF13649.6 OAG09399.1 - 0.0053 17.4 0.0 0.0088 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG09399.1 - 0.024 15.3 0.0 0.036 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 OAG09400.1 - 2.4e-24 85.9 30.6 8.1e-24 84.2 30.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Aldolase_II PF00596.21 OAG09402.1 - 1.8e-48 164.9 0.3 2.8e-48 164.3 0.3 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TetR_N PF00440.23 OAG09402.1 - 0.1 12.4 0.9 0.52 10.2 0.2 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Peptidase_M28 PF04389.17 OAG09403.1 - 2.6e-39 135.0 0.3 4.7e-39 134.1 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG09403.1 - 2.8e-13 49.7 0.3 7.3e-13 48.4 0.3 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG09403.1 - 0.00066 19.4 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Virul_Fac PF10139.9 OAG09406.1 - 0.02 13.2 0.0 0.026 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor ADH_zinc_N PF00107.26 OAG09408.1 - 3.8e-19 69.0 0.1 6e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG09408.1 - 5.2e-17 63.1 0.0 1.1e-16 62.1 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG09408.1 - 3.8e-10 39.6 0.3 1.5e-08 34.5 0.1 3.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain THF_DHG_CYH_C PF02882.19 OAG09408.1 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ELFV_dehydrog PF00208.21 OAG09408.1 - 0.017 14.8 0.3 0.026 14.2 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 OAG09408.1 - 0.069 12.6 1.0 0.11 11.9 1.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 OAG09408.1 - 0.07 12.4 1.0 0.1 11.9 1.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 OAG09408.1 - 0.14 12.2 0.5 0.23 11.6 0.5 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cutinase PF01083.22 OAG09409.1 - 2.6e-20 73.1 2.8 3.1e-20 72.9 2.8 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG09409.1 - 0.0065 16.0 0.2 0.0088 15.6 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 OAG09409.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 OAG09409.1 - 0.065 13.3 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain DUF3224 PF11528.8 OAG09409.1 - 0.08 12.7 2.8 0.59 9.9 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3224) MFS_1 PF07690.16 OAG09410.1 - 1.2e-31 110.0 28.8 1.6e-31 109.5 28.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 OAG09411.1 - 3.3e-10 41.0 7.3 1.2e-09 39.1 7.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 OAG09413.1 - 1.2e-92 311.5 0.0 1.4e-92 311.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG09413.1 - 9e-05 22.4 0.1 0.0089 15.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG09413.1 - 0.076 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family SET PF00856.28 OAG09414.1 - 1.3e-12 48.4 0.0 2.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 SET domain SAF PF08666.12 OAG09414.1 - 0.17 12.5 0.1 12 6.6 0.0 2.3 2 0 0 2 2 2 0 SAF domain AhpC-TSA_2 PF13911.6 OAG09415.1 - 1.3e-23 83.3 0.0 2.1e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 OAG09415.1 - 0.066 13.1 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family ADH_N PF08240.12 OAG09416.1 - 4e-26 91.0 1.9 8.7e-26 89.9 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG09416.1 - 9.2e-20 70.9 0.3 1.7e-19 70.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG09416.1 - 0.00036 19.9 1.0 0.00066 19.0 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 OAG09416.1 - 0.00046 20.4 0.1 0.00083 19.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 OAG09416.1 - 0.00057 19.4 0.0 0.0018 17.8 0.0 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 OAG09416.1 - 0.034 13.7 0.2 0.057 13.0 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 OAG09416.1 - 0.079 14.0 0.0 0.19 12.8 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 OAG09416.1 - 0.095 13.3 0.6 0.21 12.2 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pep_deformylase PF01327.21 OAG09416.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Polypeptide deformylase ADH_N_2 PF16884.5 OAG09416.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase MFS_1 PF07690.16 OAG09417.1 - 2.8e-18 66.0 26.0 2.8e-18 66.0 26.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fer4_15 PF13459.6 OAG09418.1 - 1.8 9.4 0.0 1.8 9.4 0.0 2.9 3 1 0 3 3 3 0 4Fe-4S single cluster domain Asp-B-Hydro_N PF05279.11 OAG09418.1 - 2.1 8.3 12.8 2.7 8.0 12.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Membralin PF09746.9 OAG09418.1 - 6.5 5.7 5.2 8.6 5.3 5.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein RR_TM4-6 PF06459.12 OAG09418.1 - 8.8 6.1 13.7 11 5.7 13.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_10 PF00331.20 OAG09419.1 - 1.6e-103 346.2 0.4 1.9e-103 345.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 OAG09419.1 - 9.8e-15 54.2 8.2 9.8e-15 54.2 8.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.15 OAG09419.1 - 0.063 12.6 0.3 0.21 10.9 0.1 1.7 1 1 1 2 2 2 0 Beta-galactosidase Methyltransf_23 PF13489.6 OAG09420.1 - 0.03 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ABM PF03992.16 OAG09422.1 - 2.2e-07 30.9 0.1 7.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase zf-C3HC4_3 PF13920.6 OAG09423.1 - 6.2e-10 38.8 5.9 1.2e-09 37.8 5.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG09423.1 - 6.5e-08 32.4 5.9 1.1e-07 31.7 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG09423.1 - 1.7e-07 31.0 5.5 3.2e-07 30.1 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG09423.1 - 4.5e-07 30.1 6.4 1e-06 29.0 6.4 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG09423.1 - 8.4e-07 28.9 1.8 1.2e-06 28.4 0.7 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG09423.1 - 1.1e-06 28.4 7.1 3.6e-06 26.7 3.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG09423.1 - 1.6e-06 27.9 9.9 2.7e-06 27.1 6.8 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 NPR3 PF03666.13 OAG09423.1 - 0.0054 15.6 0.3 0.0079 15.0 0.3 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 zf-C3HC4_4 PF15227.6 OAG09423.1 - 0.012 15.7 5.3 0.067 13.4 5.7 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAG09423.1 - 0.04 14.2 3.3 0.1 12.9 3.3 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OAG09423.1 - 0.1 12.4 4.2 0.28 11.0 4.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-4CXXC_R1 PF10497.9 OAG09423.1 - 0.13 12.5 3.3 0.3 11.3 3.3 1.7 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Zn_Tnp_IS91 PF14319.6 OAG09423.1 - 0.5 10.4 5.7 0.084 12.9 1.1 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain DNApol_Exo PF18136.1 OAG09424.1 - 2.6e-103 345.1 0.1 6e-103 343.8 0.0 1.7 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 OAG09424.1 - 5.7e-57 193.5 0.0 9.5e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A YceG_bac PF14266.6 OAG09424.1 - 0.033 13.1 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' DNA_pol_A_exo1 PF01612.20 OAG09424.1 - 0.13 11.9 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease Fungal_trans PF04082.18 OAG09430.1 - 9.8e-20 70.7 0.0 1.4e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG09430.1 - 5.5e-07 29.7 20.0 0.00042 20.6 2.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG09430.1 - 1.9e-06 28.0 12.6 2.7e-06 27.5 7.0 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG09430.1 - 0.00014 22.4 13.3 0.02 15.7 2.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DLIC PF05783.11 OAG09430.1 - 0.0042 16.0 0.8 0.0082 15.0 0.8 1.3 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) DUF2026 PF09641.10 OAG09430.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) zf-met PF12874.7 OAG09430.1 - 0.22 12.0 0.9 0.57 10.6 0.9 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type TRAF6_Z2 PF18048.1 OAG09430.1 - 1.1 9.4 4.6 6.7 6.9 1.8 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 MFS_1 PF07690.16 OAG09433.1 - 5.1e-37 127.6 43.2 7.2e-35 120.5 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG09433.1 - 3.2e-07 29.6 32.5 1.8e-06 27.1 32.5 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MatE PF01554.18 OAG09434.1 - 1e-54 184.5 19.8 1.2e-29 103.0 6.2 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAG09434.1 - 1.8e-08 34.6 7.0 1.8e-08 34.6 7.0 4.1 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 OAG09435.1 - 8.6e-90 301.0 0.0 1.1e-89 300.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAG09435.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain HET PF06985.11 OAG09436.1 - 6.8e-28 97.9 0.1 1.2e-27 97.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1713 PF08213.11 OAG09438.1 - 9.8e-12 44.6 21.1 2e-11 43.6 21.1 1.6 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) SR-25 PF10500.9 OAG09438.1 - 2.5 7.6 16.1 0.032 13.9 2.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein G-alpha PF00503.20 OAG09439.1 - 6.4e-108 361.1 1.8 7.5e-108 360.8 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG09439.1 - 2e-15 56.7 0.6 6.4e-10 38.8 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG09439.1 - 7.4e-05 22.2 3.6 0.0012 18.2 0.3 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG09439.1 - 0.035 14.3 0.2 5.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 OAG09439.1 - 0.053 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2985 PF11204.8 OAG09439.1 - 0.055 13.6 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) AAA_29 PF13555.6 OAG09439.1 - 0.1 12.4 0.2 0.36 10.6 0.2 1.9 1 1 1 2 2 2 0 P-loop containing region of AAA domain AA_permease PF00324.21 OAG09440.1 - 1e-126 423.3 34.3 1.3e-126 423.1 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG09440.1 - 2.7e-37 128.6 38.7 3.9e-37 128.1 38.7 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1754 PF08555.10 OAG09441.1 - 4.3e-15 56.3 11.4 4.3e-15 56.3 11.4 1.7 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) NARP1 PF12569.8 OAG09441.1 - 1.5 7.7 8.5 1.9 7.3 8.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4554 PF15091.6 OAG09441.1 - 5.1 5.9 4.8 5.3 5.8 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) GAF_2 PF13185.6 OAG09442.1 - 1.2e-12 48.3 0.1 4.8e-12 46.3 0.1 1.8 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 OAG09442.1 - 6.6e-06 26.8 0.0 8.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain MAP7 PF05672.11 OAG09445.1 - 0.29 10.8 14.5 0.25 11.0 10.3 2.0 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family T2SSF PF00482.23 OAG09446.1 - 0.0031 17.5 0.1 0.0062 16.5 0.1 1.4 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F HGTP_anticodon PF03129.20 OAG09446.1 - 0.17 12.1 1.4 3.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Anticodon binding domain DUF4604 PF15377.6 OAG09447.1 - 8.4e-20 71.9 18.4 9.6e-20 71.7 18.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Presenilin PF01080.17 OAG09447.1 - 6.5 5.4 7.1 7.4 5.2 7.1 1.1 1 0 0 1 1 1 0 Presenilin Glyco_transf_15 PF01793.16 OAG09448.1 - 5.6e-95 318.3 10.6 3.4e-94 315.7 10.6 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase R3H-assoc PF13902.6 OAG09448.1 - 0.028 14.8 0.2 0.087 13.2 0.1 1.8 2 0 0 2 2 2 0 R3H-associated N-terminal domain ChlI PF13541.6 OAG09448.1 - 0.19 11.6 0.0 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase DUF1682 PF07946.14 OAG09449.1 - 0.021 14.1 0.8 0.033 13.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) U3_snoRNA_assoc PF08297.11 OAG09449.1 - 0.11 13.3 3.6 0.26 12.0 3.6 1.7 1 0 0 1 1 1 0 U3 snoRNA associated PTP_N PF12453.8 OAG09449.1 - 0.19 11.5 0.1 0.4 10.4 0.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal DUF4355 PF14265.6 OAG09449.1 - 8.8 6.6 14.3 19 5.5 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) SUR7 PF06687.12 OAG09450.1 - 0.55 9.8 4.7 0.9 9.1 4.7 1.3 1 0 0 1 1 1 0 SUR7/PalI family Ran_BP1 PF00638.18 OAG09451.1 - 1.4e-49 167.4 1.2 1.4e-49 167.4 1.2 1.7 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 OAG09451.1 - 0.00024 21.0 0.2 0.0017 18.3 0.2 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 OAG09451.1 - 0.00032 20.9 0.0 0.00048 20.4 0.0 1.3 1 0 0 1 1 1 1 VID27 PH-like domain YEATS PF03366.16 OAG09452.1 - 4e-19 68.4 0.0 7.6e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 OAG09452.1 - 7e-07 29.3 0.1 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation AtuA PF07287.11 OAG09453.1 - 5e-125 416.9 0.1 6.3e-125 416.5 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA adh_short_C2 PF13561.6 OAG09454.1 - 9.8e-69 231.5 6.2 1.1e-68 231.3 6.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG09454.1 - 7.2e-53 178.9 1.6 9.5e-53 178.6 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG09454.1 - 5.5e-12 46.0 2.0 9e-12 45.3 2.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG09454.1 - 0.023 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein I_LWEQ PF01608.17 OAG09454.1 - 0.063 13.5 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 I/LWEQ domain 3HCDH_N PF02737.18 OAG09454.1 - 0.11 12.4 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 OAG09454.1 - 0.28 11.3 1.9 2 8.5 0.1 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Arf PF00025.21 OAG09455.1 - 4.4e-24 84.9 0.0 5.5e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG09455.1 - 3.1e-06 27.2 0.0 5.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG09455.1 - 0.00019 20.9 0.0 0.00051 19.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG09455.1 - 0.00047 19.4 0.3 0.66 9.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OAG09455.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 OAG09455.1 - 0.058 13.2 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OAG09455.1 - 0.059 13.5 0.0 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OAG09455.1 - 0.081 13.1 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OAG09455.1 - 0.093 13.0 0.0 0.46 10.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain APH PF01636.23 OAG09456.1 - 0.00023 21.1 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HET PF06985.11 OAG09457.1 - 5.7e-13 49.5 0.0 7.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Egh16-like PF11327.8 OAG09458.1 - 0.055 13.9 0.0 0.099 13.1 0.0 1.5 1 1 0 1 1 1 0 Egh16-like virulence factor HET PF06985.11 OAG09459.1 - 1.4e-34 119.5 0.0 2.1e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fringe PF02434.16 OAG09460.1 - 5.3e-09 35.9 0.1 6.6e-08 32.3 0.0 2.4 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 OAG09460.1 - 0.033 14.0 0.1 0.072 12.9 0.0 1.5 1 1 0 1 1 1 0 Galactosyltransferase PAN_4 PF14295.6 OAG09460.1 - 0.091 12.7 1.2 0.24 11.3 1.2 1.7 1 0 0 1 1 1 0 PAN domain Epimerase PF01370.21 OAG09461.1 - 7.5e-09 35.4 0.3 6.9e-08 32.2 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG09461.1 - 8.6e-09 35.5 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG09461.1 - 7.2e-06 25.2 0.0 4.1e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG09461.1 - 7.6e-06 25.5 0.0 0.00011 21.8 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG09461.1 - 9.4e-06 25.3 0.2 2e-05 24.2 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family AlaDh_PNT_C PF01262.21 OAG09461.1 - 6.4e-05 22.4 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OAG09461.1 - 0.0066 16.7 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 OAG09461.1 - 0.0068 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Methyltransf_23 PF13489.6 OAG09461.1 - 0.0072 16.2 0.1 2.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain NAD_binding_2 PF03446.15 OAG09461.1 - 0.0075 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OAG09461.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG09461.1 - 0.11 12.8 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_75 PF07335.11 OAG09462.1 - 1.2e-50 172.0 0.7 1.5e-50 171.7 0.7 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 p450 PF00067.22 OAG09463.1 - 3.3e-32 111.8 0.1 4.5e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG09464.1 - 1.2e-37 129.7 51.9 9.8e-37 126.7 51.9 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG09464.1 - 3.7e-10 38.9 19.8 5.6e-10 38.3 19.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4405 PF14358.6 OAG09465.1 - 0.2 12.2 4.9 16 6.1 5.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Heme_oxygenase PF01126.20 OAG09467.1 - 8.5e-14 51.8 0.0 3.6e-12 46.5 0.0 2.1 2 0 0 2 2 2 2 Heme oxygenase UQ_con PF00179.26 OAG09468.1 - 2.2e-19 69.5 0.0 3.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pex14_N PF04695.13 OAG09468.1 - 0.039 14.6 3.7 0.06 14.0 3.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_pp85 PF04637.12 OAG09468.1 - 0.84 8.0 2.3 1.1 7.5 2.3 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Sugar_tr PF00083.24 OAG09469.1 - 1.6e-81 274.5 24.3 1.9e-81 274.3 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09469.1 - 9.8e-22 77.3 33.1 1.4e-20 73.5 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG09469.1 - 0.0017 16.7 6.4 0.0034 15.7 0.5 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 OAG09470.1 - 9.3e-66 222.5 0.0 1.1e-65 222.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GH131_N PF18271.1 OAG09471.1 - 6.3e-80 268.6 1.5 7.1e-80 268.4 1.5 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 OAG09471.1 - 0.098 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain FAD_binding_3 PF01494.19 OAG09472.1 - 1.2e-10 41.2 1.8 3.3e-07 29.9 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG09472.1 - 7.9e-09 35.2 0.2 0.0027 17.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG09472.1 - 2.4e-05 23.6 0.1 0.00011 21.4 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAG09472.1 - 0.00065 19.9 0.1 0.004 17.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG09472.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAG09472.1 - 0.0054 16.4 0.3 0.34 10.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG09472.1 - 0.006 15.5 0.5 0.34 9.7 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 OAG09472.1 - 0.006 15.3 0.1 0.094 11.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAG09472.1 - 0.0071 16.9 0.2 5.3 7.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG09472.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG09472.1 - 0.094 11.7 0.4 0.46 9.5 0.4 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.25 OAG09473.1 - 1.3e-21 77.0 0.0 5.3e-17 61.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG09473.1 - 2.2e-15 56.9 0.0 2.2e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG09473.1 - 4.2e-07 30.0 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG09473.1 - 0.004 16.3 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MnmE_helical PF12631.7 OAG09473.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 MnmE helical domain HicA_toxin PF07927.12 OAG09474.1 - 0.0019 18.2 0.2 0.0085 16.1 0.1 2.1 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, Fmp27 PF10344.9 OAG09475.1 - 0.042 11.9 0.0 0.098 10.7 0.0 1.5 1 1 1 2 2 2 0 Mitochondrial protein from FMP27 Glyco_hydro_28 PF00295.17 OAG09476.1 - 3.8e-56 190.5 1.7 5.7e-56 189.9 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 OAG09476.1 - 0.0011 18.8 9.6 0.0011 18.8 9.6 2.3 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.13 OAG09476.1 - 0.034 13.4 8.1 0.025 13.9 4.6 2.1 1 1 0 2 2 2 0 Periplasmic copper-binding protein (NosD) DUF261 PF03196.13 OAG09476.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF261 PTR2 PF00854.21 OAG09477.1 - 3.4e-81 273.1 3.5 5e-81 272.6 3.5 1.2 1 0 0 1 1 1 1 POT family Cu-oxidase_2 PF07731.14 OAG09481.1 - 6e-23 81.1 0.6 5e-21 74.9 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG09481.1 - 8.5e-21 74.2 0.6 5.7e-20 71.5 0.2 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG09481.1 - 0.026 14.7 0.1 0.24 11.5 0.0 2.6 4 0 0 4 4 4 0 Multicopper oxidase DUF3176 PF11374.8 OAG09483.1 - 1.2e-11 44.7 0.4 2.5e-11 43.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) AMP-binding PF00501.28 OAG09484.1 - 2.6e-91 306.4 0.1 3.5e-91 305.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG09484.1 - 1.9e-14 54.4 0.2 5e-14 53.0 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EamA PF00892.20 OAG09485.1 - 4.6e-09 36.6 26.3 2.7e-07 30.9 3.4 2.6 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 OAG09485.1 - 6.4e-09 35.2 1.9 8.1e-09 34.9 0.9 1.7 1 1 1 2 2 2 1 Ceramide synthase regulator COX8 PF02285.15 OAG09485.1 - 0.27 11.1 1.5 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII Ank_2 PF12796.7 OAG09486.1 - 2.3e-17 63.3 0.5 5.2e-06 26.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG09486.1 - 3.4e-13 49.8 0.6 6.9e-06 26.5 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG09486.1 - 1.3e-10 41.3 0.4 9.6e-06 25.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG09486.1 - 4.7e-10 38.8 0.2 0.004 17.5 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OAG09486.1 - 2.4e-08 34.1 0.6 0.12 12.9 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeat KilA-N PF04383.13 OAG09486.1 - 6.7e-05 22.7 1.2 0.00044 20.1 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain Rubella_E2 PF05749.11 OAG09486.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 NDUF_B7 PF05676.13 OAG09487.1 - 2e-30 104.3 5.5 2.4e-30 104.0 5.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PTPA PF03095.15 OAG09488.1 - 4.5e-107 358.0 0.0 5.4e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein GSHPx PF00255.19 OAG09488.1 - 5.1e-38 129.0 0.1 7.2e-38 128.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 OAG09488.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family zf-C2H2 PF00096.26 OAG09489.1 - 0.0019 18.5 7.5 0.1 13.1 1.2 3.5 2 1 0 2 2 2 2 Zinc finger, C2H2 type DUF1459 PF07312.11 OAG09489.1 - 1.1 9.5 5.3 3.1 8.1 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) Use1 PF09753.9 OAG09491.1 - 4.5e-15 56.0 0.2 7.3e-15 55.4 0.2 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Synaptobrevin PF00957.21 OAG09491.1 - 0.04 13.7 0.0 0.04 13.7 0.0 3.3 4 0 0 4 4 4 0 Synaptobrevin DUF2730 PF10805.8 OAG09491.1 - 0.56 10.3 2.9 0.34 11.0 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) T2SSM PF04612.12 OAG09491.1 - 0.69 10.0 4.5 0.16 12.0 0.9 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF1771 PF08590.10 OAG09492.1 - 4.5e-23 81.4 10.9 4.5e-23 81.4 10.9 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAG09492.1 - 1e-12 48.2 0.8 2.9e-12 46.8 0.8 1.8 1 0 0 1 1 1 1 Smr domain FTHFS PF01268.19 OAG09492.1 - 0.016 13.4 0.2 0.049 11.8 0.0 1.7 2 0 0 2 2 2 0 Formate--tetrahydrofolate ligase DUF4407 PF14362.6 OAG09492.1 - 0.042 13.2 1.5 0.07 12.5 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_31 PF01055.26 OAG09494.1 - 1.5e-156 522.0 5.9 2.1e-156 521.5 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG09494.1 - 2.7e-37 127.5 0.6 5.3e-37 126.6 0.2 1.7 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG09494.1 - 4.4e-13 49.3 0.5 2.1e-12 47.2 0.5 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like Rotavirus_VP7 PF05868.11 OAG09494.1 - 0.062 12.7 0.9 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 Rotavirus major outer capsid protein VP7 Na_H_Exchanger PF00999.21 OAG09495.1 - 2.8e-38 131.7 21.4 3.6e-38 131.4 21.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 OAG09495.1 - 0.0092 16.1 2.2 0.032 14.3 0.6 2.8 3 0 0 3 3 3 1 YrhC-like protein CRPA PF05745.11 OAG09495.1 - 0.41 10.6 10.1 1.2 9.1 2.5 2.6 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) YwcE PF17368.2 OAG09495.1 - 2 9.1 6.1 0.54 10.9 0.6 2.8 3 0 0 3 3 3 0 Spore morphogenesis and germination YwcE DUF3042 PF11240.8 OAG09495.1 - 6.2 6.9 5.4 1.7 8.7 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) ABC_tran PF00005.27 OAG09496.1 - 1e-15 58.4 0.0 1.3e-14 54.8 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAG09496.1 - 3.8e-11 43.3 0.3 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG09496.1 - 0.00046 19.7 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG09496.1 - 0.00052 19.7 0.3 0.0041 16.8 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF3584 PF12128.8 OAG09496.1 - 0.00063 17.4 0.1 0.00085 17.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 OAG09496.1 - 0.007 16.9 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OAG09496.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 OAG09496.1 - 0.017 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 OAG09496.1 - 0.023 14.4 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 OAG09496.1 - 0.023 14.9 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG09496.1 - 0.029 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG09496.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OAG09496.1 - 0.098 13.0 1.9 0.44 10.9 1.9 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAG09496.1 - 0.11 12.8 0.2 0.24 11.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OAG09496.1 - 0.11 12.9 0.2 0.76 10.2 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 OAG09496.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 OAG09496.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG09496.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG09496.1 - 0.17 12.0 0.1 0.41 10.8 0.1 1.6 2 0 0 2 2 1 0 AAA domain Aldedh PF00171.22 OAG09497.1 - 5.8e-132 440.5 0.8 7.1e-132 440.2 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IPPT PF01715.17 OAG09498.1 - 1.1e-61 208.6 0.2 1.4e-61 208.2 0.2 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 OAG09498.1 - 2.5e-06 27.1 0.1 7.6e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 OAG09498.1 - 3.4e-05 24.0 0.7 0.00093 19.4 0.0 3.1 3 1 0 3 3 3 1 AAA domain zf-C2H2_jaz PF12171.8 OAG09498.1 - 5e-05 23.5 0.8 9.2e-05 22.6 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.6 OAG09498.1 - 0.00054 20.5 0.3 0.034 14.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG09498.1 - 0.00067 20.1 0.1 0.0026 18.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain zf-met PF12874.7 OAG09498.1 - 0.0076 16.6 0.5 0.022 15.2 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_28 PF13521.6 OAG09498.1 - 0.023 15.0 0.1 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 OAG09498.1 - 0.037 13.7 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Hpr_kinase_C PF07475.12 OAG09498.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.14 OAG09498.1 - 0.084 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OAG09498.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 OAG09498.1 - 0.13 12.7 0.1 0.84 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 OAG09498.1 - 0.13 12.1 0.1 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Tom22 PF04281.13 OAG09499.1 - 1.6e-45 154.3 1.2 1.8e-45 154.2 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Porin_3 PF01459.22 OAG09500.1 - 1.2e-80 270.8 0.0 1.4e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 OAG09501.1 - 4.7e-61 205.9 0.0 7.1e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG09501.1 - 7.6e-24 84.5 0.1 1.3e-22 80.5 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAG09501.1 - 0.097 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF1_Zn_bind PF09416.10 OAG09504.1 - 2.8e-72 241.6 0.6 7.1e-72 240.4 0.5 1.7 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) DUF5599 PF18141.1 OAG09504.1 - 4.6e-33 113.3 0.0 8e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_11 PF13086.6 OAG09504.1 - 8e-18 65.2 0.2 1.4e-17 64.4 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG09504.1 - 3e-10 40.2 0.0 8.1e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG09504.1 - 3.3e-08 34.0 0.0 2.4e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OAG09504.1 - 2.1e-05 24.6 0.0 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 OAG09504.1 - 0.018 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Helicase DEAD PF00270.29 OAG09504.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 OAG09504.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 OAG09504.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 OAG09504.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 OAG09504.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Ribosomal_S27e PF01667.17 OAG09504.1 - 2 8.2 4.4 2.4 7.9 1.4 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 PI-PLC-X PF00388.19 OAG09508.1 - 1.4e-61 206.4 0.0 2.5e-61 205.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAG09508.1 - 3.3e-41 140.2 0.0 6.8e-41 139.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAG09508.1 - 0.0075 16.5 0.0 0.03 14.6 0.0 2.0 1 1 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 OAG09508.1 - 0.015 15.7 0.2 0.045 14.2 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_10 PF14788.6 OAG09508.1 - 0.031 14.1 0.4 0.061 13.2 0.4 1.5 1 0 0 1 1 1 0 EF hand GDPD PF03009.17 OAG09508.1 - 0.048 13.4 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.32 OAG09508.1 - 0.068 12.8 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_like PF09279.11 OAG09508.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like G6B PF15096.6 OAG09508.1 - 0.12 12.2 0.0 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 G6B family Hydrolase_6 PF13344.6 OAG09510.1 - 1.8e-23 82.6 0.0 3.3e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG09510.1 - 3e-13 49.6 0.0 9.2e-13 48.1 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG09510.1 - 0.028 14.7 0.0 15 5.8 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PEP_mutase PF13714.6 OAG09512.1 - 7.4e-47 159.8 0.5 8.5e-47 159.6 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG09512.1 - 9.1e-20 70.6 0.4 1.2e-19 70.2 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family ZapB PF06005.12 OAG09513.1 - 0.0031 17.9 0.4 0.0078 16.6 0.4 1.6 1 0 0 1 1 1 1 Cell division protein ZapB bZIP_1 PF00170.21 OAG09513.1 - 0.0071 16.4 0.2 0.012 15.7 0.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor KASH_CCD PF14662.6 OAG09513.1 - 0.014 15.3 0.3 0.031 14.1 0.1 1.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH EspB_PE PF18625.1 OAG09513.1 - 0.23 11.9 0.3 0.23 11.9 0.3 2.7 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain TSC22 PF01166.18 OAG09513.1 - 0.32 11.3 1.0 6 7.3 0.5 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family adh_short_C2 PF13561.6 OAG09514.1 - 2.9e-27 95.7 0.0 4.4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG09514.1 - 7.9e-20 71.1 0.0 1.2e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG09514.1 - 0.00027 20.9 0.1 0.0013 18.7 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG09514.1 - 0.0031 17.0 0.1 0.006 16.1 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG09514.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG09514.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Kdo PF06293.14 OAG09517.1 - 2e-09 37.1 0.0 4.6e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAG09517.1 - 8.4e-09 35.2 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAG09517.1 - 6.6e-07 29.5 2.6 0.0025 17.8 0.3 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OAG09517.1 - 6.3e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 OAG09517.1 - 0.00014 21.2 0.0 0.00019 20.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG09517.1 - 0.041 12.7 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 OAG09517.1 - 0.23 10.8 0.0 0.33 10.2 0.0 1.3 1 1 0 1 1 1 0 Ecdysteroid kinase zf-MYND PF01753.18 OAG09520.1 - 3.9e-10 39.6 18.3 6.9e-10 38.9 18.3 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OAG09520.1 - 1.1 9.7 14.2 2.9 8.3 14.2 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cyclin PF08613.11 OAG09522.1 - 2.3e-12 47.6 0.0 3.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG09522.1 - 0.0036 17.0 0.1 0.0058 16.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L27A PF00828.19 OAG09525.1 - 4.2e-16 59.8 0.0 7.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DNA_pol_B PF00136.21 OAG09526.1 - 4.7e-145 483.8 0.2 6.7e-145 483.3 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAG09526.1 - 3.6e-80 269.6 0.2 5.2e-80 269.1 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAG09526.1 - 2.4e-18 66.4 8.8 7.2e-18 64.8 8.8 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 OAG09526.1 - 5.1e-05 23.1 0.3 0.00013 21.7 0.3 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 OAG09526.1 - 0.0039 16.1 0.1 0.0097 14.8 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral ETC_C1_NDUFA5 PF04716.14 OAG09526.1 - 0.031 14.1 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region RNase_H_2 PF13482.6 OAG09526.1 - 0.072 13.1 2.4 0.12 12.3 0.6 2.3 2 1 0 2 2 2 0 RNase_H superfamily Acetyltransf_10 PF13673.7 OAG09527.1 - 1e-09 38.4 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG09527.1 - 5.4e-08 33.1 0.0 8.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG09527.1 - 2.3e-07 31.1 0.0 4.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG09527.1 - 0.0002 21.4 0.0 0.00043 20.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAG09527.1 - 0.00041 20.4 0.0 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG09527.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein DivIC PF04977.15 OAG09528.1 - 0.078 12.8 5.3 0.14 11.9 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Herpes_UL25 PF01499.16 OAG09528.1 - 0.098 11.2 3.6 0.044 12.3 1.0 1.6 2 0 0 2 2 2 0 Herpesvirus UL25 family Mvb12 PF09452.10 OAG09528.1 - 0.28 11.6 1.5 1.1 9.7 0.0 2.3 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Fib_alpha PF08702.10 OAG09528.1 - 0.29 11.3 4.0 1.5 9.0 0.1 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 OAG09528.1 - 1.9 8.5 9.9 0.79 9.7 0.2 2.6 3 0 0 3 3 3 0 Prefoldin subunit Egh16-like PF11327.8 OAG09529.1 - 6.3e-55 186.4 13.6 8.6e-55 186.0 13.6 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor OPT PF03169.15 OAG09530.1 - 2.8e-172 574.6 60.0 3.2e-172 574.4 60.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3938 PF13074.6 OAG09530.1 - 0.11 12.7 1.2 0.58 10.4 1.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Amidase PF01425.21 OAG09531.1 - 1.5e-88 297.8 0.7 1.9e-88 297.4 0.7 1.1 1 0 0 1 1 1 1 Amidase DIOX_N PF14226.6 OAG09532.1 - 1.4e-25 90.3 0.0 2.3e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG09532.1 - 1.5e-17 63.9 0.0 2.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_47 PF01532.20 OAG09533.1 - 3.2e-107 359.3 0.0 3.7e-107 359.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_20 PF00728.22 OAG09534.1 - 3e-24 86.1 0.8 5.5e-18 65.5 0.0 3.0 2 1 1 3 3 3 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OAG09534.1 - 8.1e-09 36.3 0.0 8.7e-08 33.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Amidohydro_2 PF04909.14 OAG09535.1 - 1.7e-22 80.6 0.0 2.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase His_Phos_2 PF00328.22 OAG09537.1 - 3.6e-20 72.7 0.0 4.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SKG6 PF08693.10 OAG09539.1 - 2.9e-07 29.8 2.1 4.4e-07 29.2 2.1 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 OAG09539.1 - 0.1 12.0 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Mid2 PF04478.12 OAG09539.1 - 0.18 11.7 2.8 0.2 11.5 1.8 1.7 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor COesterase PF00135.28 OAG09540.1 - 1.7e-67 228.4 0.2 2.2e-67 228.1 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family NUFIP2 PF15293.6 OAG09540.1 - 0.0039 16.1 0.1 0.0059 15.6 0.1 1.1 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Abhydrolase_3 PF07859.13 OAG09540.1 - 0.028 14.3 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG09540.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3593 PF12159.8 OAG09542.1 - 0.018 15.1 1.1 0.055 13.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) DHHC PF01529.20 OAG09543.1 - 1.6e-37 128.6 9.0 1.6e-37 128.6 9.0 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3955 PF13127.6 OAG09543.1 - 0.019 14.7 3.7 0.043 13.6 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) STELLO PF03385.17 OAG09543.1 - 0.15 10.9 0.5 0.22 10.3 0.5 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases Yip1 PF04893.17 OAG09543.1 - 0.51 10.0 9.1 0.038 13.7 1.6 2.1 2 0 0 2 2 2 0 Yip1 domain zinc_ribbon_2 PF13240.6 OAG09543.1 - 1.3 8.8 5.0 2.8 7.8 5.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Amino_oxidase PF01593.24 OAG09545.1 - 7.3e-47 160.7 0.2 1.5e-38 133.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG09545.1 - 1.3e-13 50.9 0.1 2.9e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG09545.1 - 6.4e-06 25.6 0.1 3.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG09545.1 - 0.00016 22.2 1.7 0.00018 22.0 0.4 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG09545.1 - 0.00023 20.5 1.0 0.00043 19.6 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG09545.1 - 0.00082 19.1 0.2 0.0019 17.8 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG09545.1 - 0.0011 17.7 0.1 0.0018 17.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG09545.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OAG09545.1 - 0.0019 17.4 1.4 0.0035 16.5 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG09545.1 - 0.0028 16.9 0.3 0.0044 16.3 0.3 1.2 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 OAG09545.1 - 0.033 14.1 0.6 0.068 13.1 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 OAG09545.1 - 0.088 12.1 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG09545.1 - 0.1 11.8 1.0 0.18 11.0 1.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG09545.1 - 0.18 10.9 0.7 0.26 10.3 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAG09545.1 - 0.18 11.7 5.2 0.83 9.6 0.4 3.3 4 1 0 4 4 4 0 FAD-NAD(P)-binding zf-MYND PF01753.18 OAG09546.1 - 1.5e-09 37.8 15.6 2.6e-09 37.0 15.6 1.4 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 OAG09546.1 - 0.26 11.7 9.5 0.33 11.3 9.5 1.2 1 0 0 1 1 1 0 Rhodanase C-terminal zf-C6H2 PF15801.5 OAG09546.1 - 0.31 11.4 15.0 0.74 10.2 15.0 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Tubulin PF00091.25 OAG09547.1 - 1.7e-68 230.7 0.1 2.5e-68 230.2 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG09547.1 - 3.5e-44 150.0 0.9 5.2e-44 149.4 0.2 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain GDPD PF03009.17 OAG09547.1 - 2.9e-30 105.9 0.0 5.5e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Misat_Tub_SegII PF10644.9 OAG09547.1 - 8.2e-07 29.4 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain GDPD_2 PF13653.6 OAG09547.1 - 0.002 18.5 0.5 0.0063 16.9 0.5 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Tubulin_3 PF14881.6 OAG09547.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Coatomer_E PF04733.14 OAG09548.1 - 3.6e-62 210.4 7.8 4.1e-62 210.2 7.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_16 PF13432.6 OAG09548.1 - 0.00011 22.8 7.9 0.0072 16.9 0.5 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG09548.1 - 0.0002 21.0 0.7 0.0008 19.0 0.4 2.2 2 0 0 2 2 2 1 TPR repeat TPR_4 PF07721.14 OAG09548.1 - 0.00034 21.0 6.8 0.053 14.2 0.7 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG09548.1 - 0.00075 20.1 11.3 0.085 13.7 0.5 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG09548.1 - 0.0011 18.7 0.3 0.067 13.1 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG09548.1 - 0.0013 18.9 10.3 0.035 14.4 0.3 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG09548.1 - 0.0019 18.4 1.2 0.15 12.3 0.1 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAG09548.1 - 0.002 18.6 16.4 0.086 13.4 1.7 3.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG09548.1 - 0.0055 16.7 12.4 0.0064 16.5 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG09548.1 - 0.059 13.6 0.1 2.4 8.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAG09548.1 - 0.077 13.1 2.9 1.4 9.0 0.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF1400 PF07176.11 OAG09548.1 - 0.13 12.5 6.3 3.1 8.1 1.2 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) TPR_6 PF13174.6 OAG09548.1 - 0.59 10.9 4.7 42 5.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.13 OAG09548.1 - 0.64 10.2 5.2 11 6.3 0.8 2.7 2 1 0 2 2 2 0 HemY protein N-terminus Methyltransf_25 PF13649.6 OAG09549.1 - 1.4e-07 32.1 0.1 3.6e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG09549.1 - 1.4e-05 25.7 0.1 4e-05 24.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG09549.1 - 0.00064 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG09549.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 OAG09549.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.6 OAG09549.1 - 0.17 11.7 2.3 0.34 10.7 2.3 1.5 1 1 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 OAG09550.1 - 7.2e-72 240.8 0.0 1.9e-71 239.4 0.0 1.6 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OAG09550.1 - 1.7e-26 91.8 0.1 3.3e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OAG09550.1 - 0.00012 22.7 0.0 0.00021 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 OAG09550.1 - 0.0016 17.7 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 OAG09550.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAG09550.1 - 0.021 15.5 0.2 0.15 12.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF4666 PF15697.5 OAG09551.1 - 0.051 14.3 2.0 0.074 13.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) NAD_kinase PF01513.21 OAG09552.1 - 8.4e-80 268.1 0.0 1.2e-79 267.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase RHH_1 PF01402.21 OAG09552.1 - 0.13 12.2 0.0 9.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Zn_clus PF00172.18 OAG09553.1 - 7.2e-10 38.8 10.1 1.4e-09 37.9 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG09553.1 - 6.5e-09 35.2 0.1 1.2e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 OAG09555.1 - 5.7e-11 43.0 7.8 1.2e-07 32.2 3.0 3.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GATA PF00320.27 OAG09557.1 - 3.8e-15 55.2 5.3 6.5e-15 54.4 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 OAG09557.1 - 0.49 10.7 1.6 0.96 9.8 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon GCS PF03074.16 OAG09558.1 - 4.6e-177 588.9 0.0 5.5e-177 588.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Cytochrom_B561 PF03188.16 OAG09558.1 - 0.25 11.5 0.0 3.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Zn_clus PF00172.18 OAG09561.1 - 0.00015 21.8 11.0 0.00026 21.0 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFA PF04828.14 OAG09562.1 - 1.1e-14 54.6 0.5 2e-14 53.7 0.5 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3408 PF11888.8 OAG09562.1 - 2.9 8.0 9.5 0.25 11.5 5.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) ORC6 PF05460.13 OAG09563.1 - 0.083 12.1 2.3 0.11 11.8 2.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pyridoxal_deC PF00282.19 OAG09564.1 - 2.7e-111 371.9 0.0 4.9e-111 371.1 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 OAG09564.1 - 0.0095 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SPRY PF00622.28 OAG09565.1 - 0.013 15.6 0.0 0.73 10.0 0.0 3.1 3 1 0 3 3 3 0 SPRY domain Plug PF07715.15 OAG09565.1 - 0.054 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 TonB-dependent Receptor Plug Domain Bystin PF05291.11 OAG09566.1 - 9.5e-125 415.7 0.0 1.2e-124 415.3 0.0 1.1 1 0 0 1 1 1 1 Bystin NTP_transf_9 PF04248.12 OAG09567.1 - 2.1e-30 104.5 1.2 2.5e-30 104.2 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Pyr_redox_2 PF07992.14 OAG09568.1 - 1.8e-51 175.2 0.0 2.2e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG09568.1 - 1.7e-11 44.5 0.0 3.8e-10 40.2 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG09568.1 - 0.0083 15.4 0.1 3.8 6.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_DMAT PF11991.8 OAG09570.1 - 6.1e-104 348.3 0.1 9.4e-104 347.7 0.0 1.3 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Glyco_hydro_5_C PF18564.1 OAG09570.1 - 0.087 13.4 0.0 0.33 11.5 0.0 1.9 1 0 0 1 1 1 0 Glycoside hydrolase family 5 C-terminal domain COPIIcoated_ERV PF07970.12 OAG09571.1 - 7.4e-33 114.3 0.0 1.1e-32 113.7 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAG09571.1 - 2e-21 76.1 0.1 3.7e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) BRCT PF00533.26 OAG09572.1 - 2.8e-05 24.4 0.0 7.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG09572.1 - 0.0099 16.3 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OAG09572.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain STE2 PF02116.15 OAG09573.1 - 2.2e-75 253.6 18.9 2.8e-75 253.2 18.9 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF1772 PF08592.11 OAG09573.1 - 7.7 6.8 7.8 5.8 7.2 1.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) PMI_typeI PF01238.21 OAG09574.1 - 1.6e-140 468.6 0.1 1.8e-140 468.4 0.1 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Talin_middle PF09141.10 OAG09574.1 - 0.09 12.8 0.8 0.2 11.7 0.8 1.5 1 0 0 1 1 1 0 Talin, middle domain DUF1325 PF07039.11 OAG09575.1 - 3.1e-26 92.0 0.0 1.7e-25 89.6 0.0 2.0 1 1 1 2 2 2 1 SGF29 tudor-like domain Arf PF00025.21 OAG09576.1 - 2.2e-74 248.7 0.2 2.5e-74 248.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG09576.1 - 6.3e-14 52.2 0.0 8.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG09576.1 - 1.1e-12 47.9 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OAG09576.1 - 2.9e-12 46.4 0.0 3.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG09576.1 - 1e-11 44.7 1.6 1.4e-07 31.1 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OAG09576.1 - 1e-11 44.6 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG09576.1 - 0.00036 20.6 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAG09576.1 - 0.059 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Tachylectin PF14517.6 OAG09576.1 - 0.076 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Tachylectin STI1 PF17830.1 OAG09576.1 - 0.086 12.8 0.9 0.12 12.4 0.2 1.6 2 0 0 2 2 2 0 STI1 domain SpoOE-like PF09388.10 OAG09576.1 - 0.15 12.0 0.9 0.33 10.9 0.9 1.6 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Glyco_transf_8 PF01501.20 OAG09577.1 - 1.3e-11 44.5 0.0 6.7e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.27 OAG09578.1 - 6.6e-55 183.0 0.1 1e-18 67.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Piwi PF02171.17 OAG09579.1 - 2.4e-59 201.0 0.0 3.7e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAG09579.1 - 0.00016 22.3 0.0 0.00047 20.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAG09579.1 - 0.022 14.4 0.1 0.056 13.1 0.1 1.7 1 0 0 1 1 1 0 Argonaute linker 1 domain SIKE PF05769.11 OAG09580.1 - 1.4e-08 34.8 3.1 2.2e-08 34.2 3.1 1.2 1 0 0 1 1 1 1 SIKE family Lebercilin PF15619.6 OAG09580.1 - 0.0026 17.4 7.6 0.27 10.9 1.9 3.0 2 1 2 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease MCC-bdg_PDZ PF10506.9 OAG09580.1 - 0.0082 16.1 1.8 5.3 7.1 0.0 3.5 3 0 0 3 3 3 1 PDZ domain of MCC-2 bdg protein for Usher syndrome CENP-F_leu_zip PF10473.9 OAG09580.1 - 0.028 14.5 0.1 0.028 14.5 0.1 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 OAG09580.1 - 0.031 14.6 1.5 8.8 6.7 0.0 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family JAKMIP_CC3 PF16034.5 OAG09580.1 - 0.1 12.5 4.3 21 5.0 5.2 3.0 2 1 0 2 2 2 0 JAKMIP CC3 domain Phage_GP20 PF06810.11 OAG09580.1 - 0.11 12.3 0.5 4.7 7.0 0.1 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 HIP1_clath_bdg PF16515.5 OAG09580.1 - 0.19 12.4 9.3 1.4 9.6 2.0 2.5 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 OAG09580.1 - 0.42 11.1 2.3 4.8 7.7 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 OAG09580.1 - 2.7 7.8 6.6 27 4.6 0.1 3.8 3 1 1 4 4 4 0 Septum formation initiator PRKG1_interact PF15898.5 OAG09580.1 - 2.7 8.9 7.8 21 6.1 5.2 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain GIT_CC PF16559.5 OAG09580.1 - 3 7.8 7.1 4.4 7.2 0.5 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 OAG09580.1 - 8.8 7.0 13.1 13 6.4 0.4 3.7 3 1 1 4 4 4 0 SlyX RSN1_7TM PF02714.15 OAG09582.1 - 1.9e-78 263.5 25.0 3.4e-78 262.7 25.0 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAG09582.1 - 7.7e-29 101.2 6.7 4.4e-18 66.1 0.1 2.9 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAG09582.1 - 3.8e-24 85.2 5.9 3.8e-24 85.2 5.9 3.8 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAG09582.1 - 4.2e-12 46.1 0.2 4.6e-11 42.7 0.0 2.6 2 1 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF775 PF05603.12 OAG09582.1 - 0.15 11.6 1.4 0.33 10.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) tRNA_lig_CPD PF08302.11 OAG09582.1 - 0.46 9.9 8.7 0.31 10.4 6.4 1.8 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain DUF4718 PF15842.5 OAG09582.1 - 0.75 9.6 6.5 1.9 8.2 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Macoilin PF09726.9 OAG09582.1 - 1.4 7.3 17.9 0.4 9.2 5.9 2.1 2 0 0 2 2 2 0 Macoilin family Hid1 PF12722.7 OAG09582.1 - 2.4 6.2 15.0 0.32 9.1 1.1 2.3 3 0 0 3 3 3 0 High-temperature-induced dauer-formation protein PhoLip_ATPase_N PF16209.5 OAG09582.1 - 7.3 6.4 6.4 0.73 9.6 0.5 2.3 2 0 0 2 2 2 0 Phospholipid-translocating ATPase N-terminal FTA4 PF13093.6 OAG09583.1 - 2.3e-49 168.0 1.9 2.7e-49 167.8 1.9 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Pcc1 PF09341.10 OAG09585.1 - 3.1e-30 104.1 0.9 4.1e-30 103.7 0.9 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Abhydrolase_6 PF12697.7 OAG09587.1 - 6.6e-05 23.6 2.2 9.5e-05 23.1 0.9 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAG09587.1 - 0.00035 20.2 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAG09587.1 - 0.0008 19.2 0.2 0.0022 17.7 0.2 1.7 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 OAG09587.1 - 0.015 14.6 0.1 0.023 13.9 0.1 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 OAG09587.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 OAG09587.1 - 0.069 13.2 0.2 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Thioesterase domain baeRF_family2 PF18844.1 OAG09588.1 - 0.1 12.6 3.3 1.1 9.3 0.1 2.5 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 Hexapep PF00132.24 OAG09589.1 - 1.3e-11 43.7 12.5 7.4e-06 25.5 0.4 5.0 5 0 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAG09589.1 - 4e-08 32.9 6.9 3.8e-07 29.7 2.6 4.1 4 1 1 5 5 5 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OAG09589.1 - 0.042 12.8 0.1 0.052 12.5 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase Spb1_C PF07780.12 OAG09591.1 - 1.7e-67 227.1 18.7 1.7e-67 227.1 18.7 3.1 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 OAG09591.1 - 1.1e-54 185.2 0.1 2.4e-54 184.1 0.1 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OAG09591.1 - 2.1e-49 167.5 6.1 2.1e-49 167.5 6.1 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 OAG09591.1 - 0.026 14.2 0.3 0.088 12.4 0.0 2.0 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Rep_fac-A_3 PF08661.11 OAG09593.1 - 1.5e-26 92.7 0.0 1.7e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 TPR_12 PF13424.6 OAG09594.1 - 9.7e-16 57.8 3.7 4.5e-09 36.5 0.5 3.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAG09594.1 - 2e-15 56.1 6.3 1.1e-05 25.2 0.0 4.5 3 1 0 3 3 3 3 Tetratricopeptide repeat HeLo PF14479.6 OAG09595.1 - 3.1e-50 170.9 0.5 3.8e-50 170.6 0.5 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation Ses_B PF17046.5 OAG09595.1 - 6.3e-06 26.0 3.1 1.1e-05 25.2 3.1 1.4 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein Mod_r PF07200.13 OAG09595.1 - 0.025 14.7 1.3 0.21 11.7 1.8 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BAR_3 PF16746.5 OAG09595.1 - 0.049 13.3 0.3 0.12 12.1 0.1 1.7 1 1 1 2 2 2 0 BAR domain of APPL family DUF1826 PF08856.11 OAG09595.1 - 0.086 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) DUF2773 PF10971.8 OAG09595.1 - 0.09 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) GIDA_assoc PF13932.6 OAG09595.1 - 0.14 12.3 1.7 0.55 10.4 0.4 1.9 1 1 1 2 2 2 0 GidA associated domain Epimerase PF01370.21 OAG09596.1 - 0.058 12.8 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-like PF04071.12 OAG09597.1 - 0.18 11.7 1.9 14 5.6 0.8 2.3 2 0 0 2 2 2 0 Cysteine-rich small domain Polysacc_deac_1 PF01522.21 OAG09598.1 - 2.4e-16 59.7 0.0 5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG09598.1 - 1e-05 25.9 17.2 1e-05 25.9 17.2 2.0 2 0 0 2 2 2 1 Chitin recognition protein DUF2334 PF10096.9 OAG09598.1 - 0.0047 16.6 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) NTP_transf_9 PF04248.12 OAG09602.1 - 8.5e-40 134.6 3.4 1.3e-31 108.4 0.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) UEV PF05743.13 OAG09603.1 - 1.1e-28 99.5 0.0 2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 OAG09603.1 - 1.5e-20 72.9 1.0 3.5e-20 71.7 0.0 2.1 2 1 0 2 2 2 1 Vps23 core domain HAUS-augmin3 PF14932.6 OAG09603.1 - 0.0039 16.8 1.0 0.0055 16.3 1.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 OAG09603.1 - 0.05 12.5 2.2 0.072 12.0 2.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 OAG09603.1 - 0.1 11.9 2.6 0.17 11.2 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 OAG09603.1 - 0.15 12.5 4.3 0.27 11.7 4.3 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Paralemmin PF03285.15 OAG09603.1 - 0.16 11.5 0.0 0.64 9.5 0.0 2.0 1 0 0 1 1 1 0 Paralemmin DivIC PF04977.15 OAG09603.1 - 0.51 10.1 3.6 1.2 8.9 3.6 1.6 1 0 0 1 1 1 0 Septum formation initiator USP8_interact PF08941.10 OAG09603.1 - 1.7 8.4 3.5 2.5 7.9 3.5 1.2 1 0 0 1 1 1 0 USP8 interacting DivIVA PF05103.13 OAG09603.1 - 3.7 7.6 6.4 6.4 6.9 6.4 1.2 1 0 0 1 1 1 0 DivIVA protein Aminotran_5 PF00266.19 OAG09604.1 - 8.4e-96 321.1 0.0 9.7e-96 320.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG09604.1 - 9.2e-08 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAG09604.1 - 9.1e-07 28.5 0.1 4.1e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OAG09604.1 - 0.0052 15.4 0.0 0.0078 14.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-C4 PF00105.18 OAG09604.1 - 0.0098 16.3 0.6 0.023 15.1 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Pyridoxal_deC PF00282.19 OAG09604.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.18 OAG09605.1 - 9.4e-60 202.2 11.6 1.2e-59 201.9 11.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 OAG09605.1 - 6.6e-12 44.8 0.3 1.1e-11 44.2 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG09605.1 - 3.9e-07 29.8 0.1 7e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG09605.1 - 3.7e-06 26.5 0.1 8.1e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain CT_C_D PF02682.16 OAG09605.1 - 0.0065 16.2 0.3 0.015 15.1 0.3 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D TMPIT PF07851.13 OAG09605.1 - 0.21 10.8 7.6 0.039 13.2 1.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 OAG09605.1 - 0.42 11.2 11.0 6.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region PAP1 PF08601.10 OAG09605.1 - 0.49 10.1 2.2 0.68 9.6 1.4 1.6 2 0 0 2 2 2 0 Transcription factor PAP1 Ribonuc_L-PSP PF01042.21 OAG09609.1 - 2.7e-13 50.0 0.0 3.7e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_hydro_3_C PF01915.22 OAG09611.1 - 7.9e-48 163.1 0.1 1.6e-47 162.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG09611.1 - 1.5e-33 116.5 0.0 4.1e-33 115.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG09611.1 - 4.6e-21 74.7 0.0 8.8e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Dabb PF07876.12 OAG09613.1 - 6.4e-11 42.7 0.3 1.3e-10 41.8 0.3 1.5 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Ldh_2 PF02615.14 OAG09614.1 - 4.3e-125 417.3 0.9 4.9e-125 417.1 0.9 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Biotin_carb_N PF00289.22 OAG09614.1 - 0.042 14.4 0.4 2.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Biotin carboxylase, N-terminal domain Fungal_trans PF04082.18 OAG09615.1 - 2.8e-25 88.9 0.5 4.6e-25 88.2 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09615.1 - 0.00012 22.1 2.1 0.00021 21.3 2.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2827 PF10933.8 OAG09615.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) ILVD_EDD PF00920.21 OAG09616.1 - 5.3e-158 526.8 0.2 6e-158 526.7 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family TMEM210 PF15195.6 OAG09616.1 - 0.34 11.4 1.8 1.2 9.5 0.1 2.4 2 1 1 3 3 3 0 TMEM210 family adh_short_C2 PF13561.6 OAG09617.1 - 1.9e-59 201.1 0.5 1.9e-59 201.1 0.5 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG09617.1 - 4.2e-39 134.0 0.5 1e-38 132.7 0.5 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ank_2 PF12796.7 OAG09617.1 - 2.5e-11 44.0 0.0 9.3e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG09617.1 - 9.6e-11 40.9 0.6 6.7e-05 23.0 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG09617.1 - 1.5e-10 41.1 0.5 3e-06 27.4 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG09617.1 - 2.5e-09 37.2 1.9 4.9e-05 23.6 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OAG09617.1 - 7.3e-08 32.8 0.3 5.4e-06 26.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) CorA PF01544.18 OAG09617.1 - 5.1e-07 29.3 0.3 1e-06 28.3 0.3 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein KR PF08659.10 OAG09617.1 - 0.0005 20.0 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 KR domain Hydrolase_4 PF12146.8 OAG09617.1 - 0.004 16.5 0.0 0.0099 15.2 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 tRNA-synt_1c PF00749.21 OAG09621.1 - 8.1e-93 310.7 0.0 1e-92 310.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 OAG09622.1 - 3e-36 124.7 0.3 4.2e-36 124.3 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG09622.1 - 2.7e-20 72.2 3.0 4.9e-20 71.4 3.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG09622.1 - 4e-14 52.7 20.4 7.1e-14 51.9 20.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAG09622.1 - 0.0018 18.2 19.0 0.025 14.5 4.4 2.6 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAG09622.1 - 0.13 12.3 7.8 2.6 8.1 1.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 OAG09622.1 - 5 6.3 7.7 5.8 6.1 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) LSM PF01423.22 OAG09623.1 - 2.8e-19 68.6 0.0 3.4e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain HydF_dimer PF18128.1 OAG09623.1 - 0.13 12.3 0.1 2.6 8.2 0.0 2.1 1 1 0 2 2 2 0 Hydrogen maturase F dimerization domain SH3_9 PF14604.6 OAG09623.1 - 1.1 9.1 3.3 19 5.2 0.0 2.9 3 0 0 3 3 3 0 Variant SH3 domain Kinetochor_Ybp2 PF08568.10 OAG09624.1 - 7.7e-135 450.8 0.1 9.4e-135 450.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DUF1770 PF08589.10 OAG09624.1 - 0.15 13.0 3.0 2.4 9.2 0.1 3.6 4 0 0 4 4 4 0 Fungal protein of unknown function (DUF1770) Glyco_hydro_127 PF07944.12 OAG09625.1 - 5.5e-22 77.9 2.9 6.6e-20 71.1 0.5 2.5 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 AFG1_ATPase PF03969.16 OAG09626.1 - 5.3e-53 180.2 0.0 1.1e-52 179.2 0.0 1.3 1 1 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 OAG09626.1 - 3.1e-06 27.7 0.2 0.00048 20.5 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAG09626.1 - 0.00065 19.7 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG09626.1 - 0.0063 16.8 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAG09626.1 - 0.02 15.3 0.0 0.052 14.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG09626.1 - 0.085 13.3 0.0 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 RNA helicase F-box-like PF12937.7 OAG09627.1 - 7.8e-07 28.9 0.5 3.4e-06 26.9 0.2 2.3 2 0 0 2 2 2 1 F-box-like Tyr-DNA_phospho PF06087.12 OAG09628.1 - 9.1e-83 278.5 0.0 1.1e-82 278.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 OAG09628.1 - 1.1e-05 25.3 0.1 0.001 18.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain WD40 PF00400.32 OAG09630.1 - 6.2e-37 125.0 19.9 0.00011 22.9 0.0 12.0 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG09630.1 - 7.8e-09 35.7 2.1 0.27 11.5 0.0 7.1 6 2 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG09630.1 - 0.0036 16.3 0.0 7.7 5.4 0.0 4.4 5 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Mcl1_mid PF12341.8 OAG09630.1 - 0.018 14.4 1.0 2.7 7.3 0.1 3.3 3 0 0 3 3 3 0 Minichromosome loss protein, Mcl1, middle region DUF4960 PF16324.5 OAG09630.1 - 0.059 12.9 0.1 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4960) DUF4596 PF15363.6 OAG09630.1 - 0.064 13.5 0.0 0.33 11.2 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Urm1 PF09138.11 OAG09631.1 - 1.2e-33 115.3 0.0 1.4e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 OAG09631.1 - 0.0059 17.2 0.0 0.0069 17.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family Pex24p PF06398.11 OAG09632.1 - 1.6e-86 290.6 0.0 2e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 OAG09632.1 - 0.0023 16.4 1.5 0.0046 15.4 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3292) H_kinase_N PF12282.8 OAG09632.1 - 0.094 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Signal transduction histidine kinase DASH_Dam1 PF08653.10 OAG09632.1 - 0.18 11.7 0.5 0.66 9.8 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 Pkinase PF00069.25 OAG09633.1 - 8.1e-52 176.2 0.0 1.4e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG09633.1 - 7.4e-19 68.0 0.0 1.4e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG09633.1 - 0.025 14.5 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family IDO PF01231.18 OAG09634.1 - 8.6e-166 552.0 0.0 9.8e-166 551.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CsbD PF05532.12 OAG09635.1 - 5.6e-11 42.2 23.0 1.1e-09 38.0 7.4 3.3 2 1 1 3 3 3 3 CsbD-like Gly-zipper_Omp PF13488.6 OAG09635.1 - 0.29 11.2 9.8 0.23 11.5 1.9 3.2 3 0 0 3 3 3 0 Glycine zipper Pmp3 PF01679.17 OAG09636.1 - 1.5e-24 85.9 8.1 1.6e-24 85.8 8.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CNOT11 PF10155.9 OAG09637.1 - 3.5e-11 43.3 0.0 2.3e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 DUF3772 PF12607.8 OAG09637.1 - 0.047 13.4 0.3 0.15 11.9 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Egh16-like PF11327.8 OAG09638.1 - 7.5e-70 235.1 14.6 1.5e-69 234.1 14.6 1.5 1 1 0 1 1 1 1 Egh16-like virulence factor FliT PF05400.13 OAG09639.1 - 1.6 9.6 11.2 0.41 11.5 4.2 2.6 1 1 1 2 2 2 0 Flagellar protein FliT RAC_head PF16717.5 OAG09639.1 - 3.5 8.6 5.3 8.5 7.4 0.4 2.7 1 1 1 2 2 2 0 Ribosome-associated complex head domain AAA PF00004.29 OAG09640.1 - 3.7e-11 43.6 2.3 4.8e-05 23.8 0.1 2.7 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG09640.1 - 0.00064 20.1 0.0 0.0021 18.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 OAG09640.1 - 0.036 13.4 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 OAG09640.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG09640.1 - 0.064 13.6 0.3 0.16 12.3 0.3 1.7 1 0 0 1 1 1 0 AAA domain EF-hand_6 PF13405.6 OAG09640.1 - 0.085 12.8 0.3 0.31 11.1 0.3 1.9 1 0 0 1 1 1 0 EF-hand domain AAA_22 PF13401.6 OAG09640.1 - 0.09 13.0 1.6 0.6 10.4 0.3 2.8 1 1 1 2 2 2 0 AAA domain Torsin PF06309.11 OAG09640.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Torsin DUF1690 PF07956.11 OAG09640.1 - 0.19 12.1 2.1 2.4 8.6 0.4 2.7 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF3573 PF12097.8 OAG09640.1 - 0.22 10.3 0.3 0.38 9.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) adh_short_C2 PF13561.6 OAG09642.1 - 2.7e-41 141.7 0.0 8.8e-38 130.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG09642.1 - 7.8e-39 133.2 0.0 9.2e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG09642.1 - 5e-11 42.8 0.0 7.2e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG09642.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fibrillarin PF01269.17 OAG09642.1 - 0.15 11.2 0.2 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 Fibrillarin Abhydrolase_4 PF08386.10 OAG09644.1 - 1.4e-21 76.5 0.0 3e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 OAG09644.1 - 2.4e-17 63.4 0.0 1.1e-16 61.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 OAG09646.1 - 2.4e-12 46.3 0.0 2.5e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 OAG09647.1 - 2.5e-21 76.6 0.0 5.8e-21 75.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 GDPD PF03009.17 OAG09648.1 - 4.2e-09 36.5 0.0 4.8e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family p450 PF00067.22 OAG09649.1 - 7.2e-64 216.2 0.0 8.3e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4632 PF15451.6 OAG09649.1 - 0.035 14.2 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) FixS PF03597.15 OAG09649.1 - 0.13 12.0 0.3 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type MFS_1 PF07690.16 OAG09650.1 - 2.7e-33 115.4 24.5 4.2e-33 114.7 24.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG09650.1 - 1.6e-08 34.2 3.7 1.6e-08 34.2 3.7 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Orthoreo_P10 PF07204.11 OAG09650.1 - 0.067 13.2 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Mito_carr PF00153.27 OAG09652.1 - 2.9e-51 171.3 7.2 6.9e-18 64.4 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 OAG09653.1 - 5.1e-25 88.0 0.1 8e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09653.1 - 6.3e-09 35.8 10.7 9.9e-09 35.2 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.13 OAG09654.1 - 1.3e-96 323.8 0.7 5.8e-87 292.1 0.2 2.0 2 0 0 2 2 2 2 PrpF protein p450 PF00067.22 OAG09655.1 - 1.6e-66 225.0 0.0 2e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRP72 PF08492.12 OAG09655.1 - 8.1 7.0 6.0 0.48 10.9 0.4 1.8 2 0 0 2 2 2 0 SRP72 RNA-binding domain Na_Ca_ex PF01699.24 OAG09656.1 - 4.3e-35 120.9 32.1 3.7e-18 65.9 14.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Sugar_tr PF00083.24 OAG09657.1 - 1.6e-62 211.9 18.6 1.9e-62 211.6 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09657.1 - 2.8e-17 62.7 35.0 1.8e-16 60.0 32.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG09657.1 - 0.0089 14.9 17.1 0.071 12.0 6.8 2.2 1 1 1 2 2 2 2 MFS_1 like family RNase_P_p30 PF01876.16 OAG09657.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit p30 Npa1 PF11707.8 OAG09658.1 - 1.8e-92 310.4 0.0 8.7e-92 308.1 0.0 2.2 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 OAG09658.1 - 6.6e-59 198.9 0.1 2.8e-58 196.8 0.0 2.2 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Glyco_hydro_72 PF03198.14 OAG09661.1 - 1.8e-106 356.0 2.8 2.4e-106 355.6 2.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 OAG09661.1 - 2.6e-19 69.7 5.9 6.3e-19 68.4 5.9 1.6 1 0 0 1 1 1 1 X8 domain DUF3042 PF11240.8 OAG09661.1 - 0.094 12.8 0.1 0.094 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) NMD3 PF04981.13 OAG09662.1 - 1.2e-78 264.0 0.9 2.1e-78 263.2 0.9 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 OAG09662.1 - 0.0024 17.8 4.3 0.71 10.0 1.3 2.6 2 1 0 2 2 2 2 Double zinc ribbon zf_UBZ PF18439.1 OAG09662.1 - 0.083 12.5 0.6 8.4 6.1 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 OAG09662.1 - 0.2 11.7 4.6 6.4 6.8 0.6 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_recom PF13408.6 OAG09662.1 - 0.66 10.5 5.3 4.6 7.8 0.9 2.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.12 OAG09662.1 - 2.7 8.1 10.2 0.99 9.4 0.5 2.9 2 1 0 2 2 2 0 zinc-ribbons FYVE PF01363.21 OAG09662.1 - 4.8 7.4 7.3 2.3 8.4 0.1 2.6 3 0 0 3 3 3 0 FYVE zinc finger Tnp_zf-ribbon_2 PF13842.6 OAG09662.1 - 6.7 7.6 6.8 1.2 9.9 0.4 2.7 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon RsfS PF02410.15 OAG09663.1 - 1.6e-15 57.3 0.0 9.4e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation HTH_51 PF18558.1 OAG09664.1 - 0.21 11.5 0.0 0.49 10.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 OAG09665.1 - 2.4e-40 138.6 40.8 4.7e-39 134.3 42.2 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG09665.1 - 2.7e-10 39.3 15.6 4.2e-10 38.7 15.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 4HBT PF03061.22 OAG09665.1 - 1.8e-09 37.8 2.2 1.9e-09 37.7 0.2 2.1 2 0 0 2 2 2 1 Thioesterase superfamily OATP PF03137.20 OAG09665.1 - 0.00054 18.4 1.6 0.0056 15.0 0.9 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 OAG09666.1 - 0.047 13.8 14.3 0.11 12.7 14.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FYVE_2 PF02318.16 OAG09669.1 - 0.15 12.2 22.5 1.4 9.1 5.0 3.4 3 0 0 3 3 3 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 OAG09669.1 - 0.98 9.3 33.9 0.12 12.3 3.5 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.12 OAG09669.1 - 7.7 6.2 19.3 0.84 9.3 3.0 3.2 3 0 0 3 3 3 0 Cd27 binding protein (Siva) DUF4385 PF14328.6 OAG09672.1 - 4e-55 185.9 5.9 4.8e-55 185.6 5.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) Abhydrolase_3 PF07859.13 OAG09674.1 - 3.4e-11 43.4 0.6 3.3e-10 40.2 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG09674.1 - 1.1e-06 29.4 1.4 1.6e-06 28.9 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 OAG09674.1 - 4.3e-05 22.6 0.3 0.049 12.5 0.1 2.1 2 0 0 2 2 2 2 Carboxylesterase family Lipase PF00151.19 OAG09674.1 - 0.066 12.5 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Lipase DUF2235 PF09994.9 OAG09674.1 - 0.087 12.2 0.1 0.17 11.2 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2974 PF11187.8 OAG09674.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1749 PF08538.10 OAG09674.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.25 OAG09674.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 OAG09674.1 - 0.14 11.4 0.0 0.71 9.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RNase_P_Rpp14 PF01900.19 OAG09676.1 - 1.7e-36 124.5 0.0 2.9e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Rpp14/Pop5 family Synaptobrevin PF00957.21 OAG09677.1 - 6.3e-31 106.0 0.0 8.4e-31 105.6 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAG09677.1 - 1.3e-18 66.8 0.1 1.8e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain CPSase_L_D2 PF02786.17 OAG09678.1 - 8.5e-114 378.3 0.4 7.8e-83 277.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 OAG09678.1 - 3e-49 167.4 0.0 8.1e-49 166.0 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 OAG09678.1 - 7.9e-47 158.3 0.0 1.6e-46 157.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 OAG09678.1 - 2.5e-44 150.9 0.0 5.5e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 OAG09678.1 - 1.5e-40 138.3 0.1 3.5e-40 137.1 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 OAG09678.1 - 2.5e-33 115.4 0.0 5.8e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 OAG09678.1 - 2.1e-19 69.5 0.0 1.2e-18 67.1 0.0 2.5 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 OAG09678.1 - 2e-17 63.4 0.7 8.2e-09 35.3 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG09678.1 - 2.1e-15 56.7 0.1 1.4e-06 28.0 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAG09678.1 - 1.8e-09 37.4 0.1 9.1e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DJ-1_PfpI PF01965.24 OAG09678.1 - 5.8e-07 29.5 0.1 0.0036 17.1 0.0 4.3 4 0 0 4 4 4 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 OAG09678.1 - 1.9e-06 27.8 0.1 0.00031 20.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 OAG09678.1 - 5.2e-05 23.4 0.5 0.23 11.5 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 OAG09678.1 - 0.00012 21.7 0.1 0.1 12.2 0.1 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 OAG09678.1 - 0.0014 18.4 0.2 2.1 8.1 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HAMP_N3 PF18575.1 OAG09678.1 - 0.17 11.5 0.0 3.9 7.1 0.0 2.9 3 0 0 3 3 3 0 HAMP N-terminal domain 3 Ion_trans PF00520.31 OAG09679.1 - 5.8e-09 35.5 20.4 1.1e-08 34.7 20.4 1.4 1 0 0 1 1 1 1 Ion transport protein F-box-like_2 PF13013.6 OAG09680.1 - 0.036 14.1 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain Pilin_N PF07790.11 OAG09681.1 - 0.001 20.0 0.1 0.0029 18.5 0.1 1.8 1 0 0 1 1 1 1 Archaeal Type IV pilin, N-terminal DUF282 PF03380.14 OAG09681.1 - 0.0061 16.5 0.4 0.013 15.4 0.4 1.5 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF282 DUF908 PF06012.12 OAG09681.1 - 0.11 11.9 8.2 1.1 8.6 2.9 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF4834 PF16118.5 OAG09681.1 - 0.2 12.6 1.5 0.44 11.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Aa_trans PF01490.18 OAG09682.1 - 5.8e-41 140.5 29.0 6.8e-41 140.3 29.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Clr2_transil PF16761.5 OAG09683.1 - 2.8e-23 82.5 0.8 5.5e-23 81.6 0.8 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 OAG09683.1 - 7.3e-13 49.5 2.1 1.4e-12 48.6 0.1 2.4 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 SNF2_N PF00176.23 OAG09684.1 - 1.2e-58 198.5 0.1 4e-58 196.8 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG09684.1 - 9.2e-12 45.3 0.1 8.5e-11 42.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG09684.1 - 3.6e-06 27.1 0.2 1.2e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PHD PF00628.29 OAG09684.1 - 3e-05 23.8 3.7 3e-05 23.8 3.7 2.9 2 1 0 2 2 2 1 PHD-finger PhoH PF02562.16 OAG09684.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein C1_1 PF00130.22 OAG09684.1 - 3.3 7.7 22.5 4.4 7.3 4.5 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 OAG09684.1 - 3.9 7.7 15.5 2.4 8.3 2.3 2.9 3 0 0 3 3 3 0 KIAA1045 RING finger Closter_coat PF01785.17 OAG09685.1 - 0.048 12.9 0.1 6.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Closterovirus coat protein Myc-LZ PF02344.15 OAG09685.1 - 0.099 12.7 1.2 1.3 9.2 0.4 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain Molybdopterin PF00384.22 OAG09685.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Snapin_Pallidin PF14712.6 OAG09685.1 - 0.29 11.6 1.3 0.68 10.4 0.1 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Spy1 PF11357.8 OAG09685.1 - 0.43 10.9 1.7 7.2 6.9 0.6 2.3 2 0 0 2 2 2 0 Cell cycle regulatory protein DUF775 PF05603.12 OAG09686.1 - 5e-67 225.3 0.0 5.6e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) HD PF01966.22 OAG09687.1 - 4.4e-05 23.7 0.1 6.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OAG09687.1 - 0.049 13.4 0.5 0.076 12.8 0.5 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme HDOD PF08668.12 OAG09687.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 HDOD domain DUF1358 PF07096.11 OAG09687.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) Putative_PNPOx PF01243.20 OAG09688.1 - 4.9e-21 74.7 0.0 8.1e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 OAG09688.1 - 5.2e-21 74.5 5.0 1.4e-20 73.1 5.0 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 OAG09688.1 - 8.4e-07 29.5 0.1 1.4e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Imm74 PF15603.6 OAG09688.1 - 0.003 17.7 0.1 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 Immunity protein 74 IPK PF03770.16 OAG09689.1 - 4e-55 186.8 0.0 4.8e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CLP1_P PF16575.5 OAG09690.1 - 2.5e-35 122.0 0.0 5.2e-35 120.9 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 OAG09690.1 - 3.9e-33 113.5 0.1 6.4e-33 112.8 0.1 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 OAG09690.1 - 5.3e-25 88.1 0.0 8.7e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 OAG09690.1 - 8.3e-06 25.8 0.0 3.9e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAG09690.1 - 4.3e-05 23.6 0.0 0.00028 20.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG09690.1 - 0.0054 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_35 PF14516.6 OAG09690.1 - 0.0088 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain SRPRB PF09439.10 OAG09690.1 - 0.014 14.8 0.0 0.047 13.1 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OAG09690.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 OAG09690.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OAG09690.1 - 0.038 13.7 0.0 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 OAG09690.1 - 0.039 14.2 0.0 0.093 13.0 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 OAG09690.1 - 0.094 12.3 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Glyco_hydro_125 PF06824.11 OAG09691.1 - 8.5e-180 598.1 0.0 1e-179 597.8 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) TPR_12 PF13424.6 OAG09692.1 - 1.6e-23 82.8 22.0 2e-09 37.6 0.2 6.3 2 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAG09692.1 - 6.9e-19 67.1 18.8 2.5e-06 27.1 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAG09692.1 - 1.2e-05 25.0 6.0 0.4 10.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG09692.1 - 3.3e-05 23.5 6.7 0.93 9.4 0.1 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG09692.1 - 0.00014 21.7 11.2 3.4 8.0 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_14 PF13173.6 OAG09692.1 - 0.0041 17.1 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG09692.1 - 0.0075 16.7 0.0 0.032 14.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAG09692.1 - 0.018 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG09692.1 - 0.026 14.8 0.0 0.12 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain NIDO PF06119.14 OAG09692.1 - 0.053 14.5 0.0 4 8.4 0.0 2.6 2 0 0 2 2 2 0 Nidogen-like TPR_19 PF14559.6 OAG09692.1 - 0.12 12.9 4.7 2.1 8.9 0.0 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG09692.1 - 1.4 9.9 5.8 21 6.3 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_portal PF04860.12 OAG09694.1 - 0.26 10.4 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein UPF0086 PF01868.16 OAG09696.1 - 6.2e-31 106.2 0.3 9.6e-31 105.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Dyp_perox PF04261.12 OAG09697.1 - 3e-07 29.8 0.0 1.6e-05 24.1 0.0 2.7 2 1 0 2 2 2 2 Dyp-type peroxidase family PD40 PF07676.12 OAG09697.1 - 0.19 11.7 0.7 0.96 9.5 0.1 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Fungal_trans PF04082.18 OAG09698.1 - 3.6e-25 88.5 0.3 5.8e-25 87.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09698.1 - 9.6e-08 32.0 7.8 1.6e-07 31.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_33 PF10017.9 OAG09700.1 - 1.1e-91 307.2 0.0 1.5e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 OAG09700.1 - 2.1e-17 63.6 0.1 1e-15 58.0 0.1 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OAG09700.1 - 1e-05 26.1 5.1 2.4e-05 24.8 4.6 1.9 1 1 1 2 2 2 1 DinB superfamily PEMT PF04191.13 OAG09702.1 - 8e-61 203.0 8.1 1.3e-36 125.2 0.6 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 OAG09702.1 - 0.0086 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 OAG09702.1 - 0.14 12.7 0.0 2.1 8.9 0.0 2.3 1 1 0 2 2 2 0 SKICH domain Lon_C PF05362.13 OAG09703.1 - 1.7e-66 223.7 0.1 3.3e-66 222.7 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAG09703.1 - 6.1e-29 101.4 0.2 1.4e-28 100.2 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAG09703.1 - 8.7e-24 84.4 0.0 1.8e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG09703.1 - 3.4e-09 36.8 0.0 8.9e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OAG09703.1 - 1.6e-07 31.2 0.2 1.5e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase DUF4360 PF14273.6 OAG09703.1 - 6.1e-06 26.2 0.0 2.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) AAA_16 PF13191.6 OAG09703.1 - 2.8e-05 24.6 1.1 7.4e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OAG09703.1 - 4.5e-05 23.3 0.0 9.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 OAG09703.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG09703.1 - 0.00048 19.9 0.0 0.0018 18.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OAG09703.1 - 0.00055 19.2 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 OAG09703.1 - 0.00074 19.8 0.0 0.015 15.6 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OAG09703.1 - 0.0012 18.9 0.0 0.0043 17.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAG09703.1 - 0.0046 17.1 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 OAG09703.1 - 0.011 14.7 0.2 0.52 9.2 0.1 2.2 2 0 0 2 2 2 0 PrkA AAA domain RNA_helicase PF00910.22 OAG09703.1 - 0.014 15.7 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 OAG09703.1 - 0.015 14.6 0.2 0.053 12.9 0.2 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OAG09703.1 - 0.017 15.0 0.0 0.079 12.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 OAG09703.1 - 0.023 15.2 0.1 0.023 15.2 0.1 2.7 1 1 1 2 2 1 0 AAA domain AAA_7 PF12775.7 OAG09703.1 - 0.034 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 OAG09703.1 - 0.047 14.2 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG09703.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OAG09703.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAG09703.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 OAG09703.1 - 0.072 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAG09703.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 OAG09703.1 - 0.084 13.4 0.4 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 OAG09703.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG09703.1 - 0.12 12.7 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAG09703.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 OAG09703.1 - 0.17 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain HET PF06985.11 OAG09704.1 - 6.6e-12 46.0 7.1 6.1e-10 39.6 1.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AHD PF17793.1 OAG09705.1 - 0.019 14.8 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 ANC1 homology domain (AHD) GMC_oxred_N PF00732.19 OAG09706.1 - 1.5e-31 109.9 0.0 2.2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG09706.1 - 1.1e-29 103.8 0.0 2.2e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Cwf_Cwc_15 PF04889.12 OAG09708.1 - 0.5 10.1 11.2 0.32 10.7 9.8 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAD_binding_4 PF01565.23 OAG09709.1 - 1.1e-22 80.3 0.5 1.8e-22 79.6 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG09709.1 - 1.9e-12 47.1 0.5 4.1e-12 46.0 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3593 PF12159.8 OAG09710.1 - 0.09 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Cofilin_ADF PF00241.20 OAG09711.1 - 9.4e-20 70.6 0.0 1.2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 OAG09712.1 - 1.2e-36 125.5 0.0 2.1e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.22 OAG09713.1 - 1.4e-59 200.3 0.2 1.7e-59 200.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG09713.1 - 1.9e-20 73.3 0.0 3.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG09713.1 - 6.7e-09 35.4 0.0 7.7e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG09713.1 - 1.5e-06 27.9 0.3 8.1e-06 25.5 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG09713.1 - 4.3e-05 23.5 0.3 0.15 11.9 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OAG09713.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OAG09713.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OAG09713.1 - 0.0021 18.1 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OAG09713.1 - 0.083 12.7 2.3 0.61 9.8 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein LRR_9 PF14580.6 OAG09715.1 - 8.3e-41 139.4 0.0 1e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OAG09715.1 - 2.9e-09 37.1 7.0 1.3e-06 28.6 1.6 2.7 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG09715.1 - 5.9e-07 29.2 3.0 7.6e-07 28.8 1.6 1.9 2 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 OAG09715.1 - 0.032 14.3 0.2 25 5.3 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeat Glyco_hydro_32C PF08244.12 OAG09716.1 - 6e-25 88.1 1.7 9.7e-25 87.4 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 OAG09716.1 - 1.8e-17 63.9 0.0 2.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain 3-dmu-9_3-mt PF06983.13 OAG09717.1 - 5.9e-37 126.8 0.1 7.6e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase PKD PF00801.20 OAG09717.1 - 0.036 13.9 0.6 0.99 9.3 0.0 2.4 2 1 0 2 2 2 0 PKD domain DUF3328 PF11807.8 OAG09719.1 - 6.2e-34 117.7 0.2 6.6e-34 117.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Rhomboid PF01694.22 OAG09720.1 - 1.6e-17 63.9 13.5 1.6e-17 63.9 13.5 1.7 2 0 0 2 2 2 1 Rhomboid family DUF3947 PF13135.6 OAG09720.1 - 0.012 15.8 1.4 0.023 14.9 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Sugar_tr PF00083.24 OAG09722.1 - 2.8e-92 309.9 19.7 3.5e-92 309.6 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09722.1 - 5e-27 94.8 22.2 5e-27 94.8 22.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAG09722.1 - 8.5e-06 24.3 0.2 8.5e-06 24.3 0.2 2.3 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2530 PF10745.9 OAG09722.1 - 0.54 10.5 8.4 0.11 12.8 2.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Cyclase PF04199.13 OAG09723.1 - 2.8e-13 50.3 0.1 1.8e-12 47.7 0.0 1.8 1 1 1 2 2 2 1 Putative cyclase Cupin_3 PF05899.12 OAG09723.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HMG_box PF00505.19 OAG09723.1 - 0.065 13.7 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box AtuA PF07287.11 OAG09724.1 - 4.3e-120 400.6 0.2 6.5e-120 400.0 0.2 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA ADH_zinc_N PF00107.26 OAG09724.1 - 0.00075 19.5 0.0 0.091 12.7 0.0 2.7 2 1 0 2 2 2 2 Zinc-binding dehydrogenase YoaP PF14268.6 OAG09724.1 - 0.076 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 YoaP-like Sugar_tr PF00083.24 OAG09725.1 - 1.5e-24 86.7 15.4 1.7e-24 86.5 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09725.1 - 3.2e-11 42.7 17.3 3.7e-11 42.6 17.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG09725.1 - 0.00011 20.7 8.8 0.00014 20.5 8.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_61 PF03443.14 OAG09726.1 - 8.9e-47 159.7 0.0 1.6e-46 158.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Rib_5-P_isom_A PF06026.14 OAG09727.1 - 5.4e-41 140.1 0.0 1.1e-40 139.0 0.0 1.5 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 OAG09727.1 - 0.022 14.7 0.5 2.3 8.1 0.5 2.2 1 1 0 1 1 1 0 DeoR C terminal sensor domain Sugar-bind PF04198.13 OAG09727.1 - 0.089 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain ThiF PF00899.21 OAG09728.1 - 9.9e-13 48.0 0.0 2.2e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 ThiF family PRCC PF10253.9 OAG09729.1 - 0.0016 19.3 0.4 0.0022 18.8 0.4 1.3 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Aldedh PF00171.22 OAG09730.1 - 1.5e-129 432.5 0.0 1.7e-129 432.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG09730.1 - 0.00023 20.3 0.1 0.0016 17.5 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) VapB_antitoxin PF09957.9 OAG09730.1 - 0.063 13.2 0.5 0.16 11.9 0.5 1.7 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB Bac_globin PF01152.21 OAG09730.1 - 0.15 12.2 0.0 0.45 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial-like globin Fungal_trans PF04082.18 OAG09731.1 - 1.6e-30 106.1 0.0 4.8e-30 104.5 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09731.1 - 0.035 14.2 0.1 0.064 13.4 0.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 OAG09731.1 - 0.63 10.2 4.2 1.2 9.3 1.4 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain FMN_dh PF01070.18 OAG09733.1 - 8.4e-115 383.5 0.0 1e-114 383.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG09733.1 - 3.7e-21 75.0 0.1 7.2e-21 74.1 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG09733.1 - 3.9e-05 23.0 0.1 7.7e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAG09733.1 - 0.00034 20.1 0.0 0.00065 19.2 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 OAG09733.1 - 0.00097 18.5 0.0 0.082 12.2 0.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 OAG09733.1 - 0.0036 16.4 0.5 0.014 14.4 0.1 2.2 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Zn_clus PF00172.18 OAG09735.1 - 2.2e-08 34.1 12.7 3.6e-08 33.4 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_ATPase_C PF00689.21 OAG09737.1 - 5.4e-45 153.3 7.8 5.4e-45 153.3 7.8 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAG09737.1 - 6.9e-37 126.7 0.5 6.9e-37 126.7 0.5 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OAG09737.1 - 5.6e-18 66.0 0.2 1.4e-17 64.7 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG09737.1 - 2.9e-17 62.5 0.0 5.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG09737.1 - 1.1e-05 25.1 0.1 3e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG09737.1 - 0.0052 16.6 0.6 0.02 14.6 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LMF1 PF06762.14 OAG09737.1 - 2.5 7.1 5.3 2.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Lipase maturation factor Glyco_hydro_43 PF04616.14 OAG09738.1 - 1.6e-66 224.6 12.7 1.3e-57 195.4 3.4 2.4 2 1 1 3 3 3 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAG09738.1 - 7.9e-09 35.5 0.1 0.0017 18.0 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Zn_clus PF00172.18 OAG09739.1 - 6.8e-11 42.1 9.6 1e-10 41.5 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG09739.1 - 0.0028 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfate_transp PF00916.20 OAG09740.1 - 4.6e-85 285.7 19.6 6.1e-85 285.3 19.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG09740.1 - 6.8e-10 38.6 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OAG09740.1 - 6.9e-05 23.1 0.2 0.00016 21.9 0.2 1.6 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.6 OAG09740.1 - 0.013 15.0 1.6 0.034 13.7 1.6 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB EMP24_GP25L PF01105.24 OAG09743.1 - 1.4e-45 155.5 0.2 1.6e-45 155.3 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1408 PF07193.11 OAG09743.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Myb_DNA-binding PF00249.31 OAG09744.1 - 1.8e-05 24.9 2.2 0.00049 20.2 0.1 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG09744.1 - 0.0044 17.2 2.7 0.0082 16.4 0.1 2.6 2 1 1 3 3 3 1 Myb-like DNA-binding domain MSP1_C PF07462.11 OAG09744.1 - 0.0075 15.0 0.4 0.012 14.4 0.4 1.2 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus Sugar_tr PF00083.24 OAG09745.1 - 6.5e-83 279.1 22.7 8.1e-83 278.8 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09745.1 - 4.2e-29 101.6 45.2 7.7e-23 81.0 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG09745.1 - 0.01 14.7 8.1 0.019 13.9 1.6 2.4 1 1 1 2 2 2 0 MFS_1 like family TMEM192 PF14802.6 OAG09745.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 TMEM192 family PE_PPE_C PF12484.8 OAG09745.1 - 0.36 11.8 2.4 12 6.8 0.2 2.7 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal APG6_N PF17675.1 OAG09746.1 - 0.0055 17.2 15.6 0.55 10.8 10.7 2.1 1 1 1 2 2 2 2 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 OAG09746.1 - 0.0093 16.2 16.0 0.064 13.5 16.0 1.8 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 CHIP_TPR_N PF18391.1 OAG09746.1 - 0.019 15.7 9.0 0.019 15.7 9.0 1.9 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Rootletin PF15035.6 OAG09746.1 - 0.026 14.6 1.3 0.026 14.6 1.3 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 OAG09746.1 - 0.028 14.5 14.1 0.35 10.9 2.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 OAG09746.1 - 0.047 14.3 11.7 0.097 13.3 1.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Phage_GP20 PF06810.11 OAG09746.1 - 0.059 13.2 16.5 0.13 12.1 14.5 2.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF812 PF05667.11 OAG09746.1 - 0.059 12.2 14.4 0.07 12.0 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Herpes_BLRF2 PF05812.12 OAG09746.1 - 0.15 12.2 9.8 0.35 11.0 9.8 1.7 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein HalX PF08663.10 OAG09746.1 - 0.15 12.4 3.4 0.94 9.9 0.3 2.4 2 0 0 2 2 2 0 HalX domain DASH_Spc34 PF08657.10 OAG09746.1 - 0.29 10.9 10.2 0.84 9.4 4.1 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 AATF-Che1 PF13339.6 OAG09746.1 - 0.34 11.6 8.2 0.44 11.2 8.2 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF2381 PF09544.10 OAG09746.1 - 0.4 10.2 6.1 0.53 9.8 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) DUF4407 PF14362.6 OAG09746.1 - 0.41 10.0 8.7 0.55 9.5 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 OAG09746.1 - 0.43 10.6 7.1 1.7 8.7 5.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 OAG09746.1 - 0.47 9.8 10.5 0.54 9.6 10.5 1.1 1 0 0 1 1 1 0 FAM76 protein KxDL PF10241.9 OAG09746.1 - 0.48 10.7 8.3 0.18 12.1 5.1 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein UPF0449 PF15136.6 OAG09746.1 - 0.52 10.8 10.3 0.37 11.3 7.8 1.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF3552 PF12072.8 OAG09746.1 - 0.63 9.4 18.0 2.1 7.7 18.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF641 PF04859.12 OAG09746.1 - 0.73 10.2 12.9 0.21 11.9 6.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) OmpH PF03938.14 OAG09746.1 - 0.77 10.1 17.6 5.4 7.4 16.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 OAG09746.1 - 0.87 8.6 8.4 1.1 8.3 8.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med21 PF11221.8 OAG09746.1 - 1.6 9.0 12.9 4.1 7.7 7.9 2.3 1 1 0 2 2 2 0 Subunit 21 of Mediator complex Fzo_mitofusin PF04799.13 OAG09746.1 - 1.6 8.2 8.5 0.39 10.3 2.1 2.0 1 1 1 2 2 2 0 fzo-like conserved region ZapB PF06005.12 OAG09746.1 - 6 7.4 15.9 3.9e+03 -1.6 15.9 2.6 1 1 0 1 1 1 0 Cell division protein ZapB F-box-like PF12937.7 OAG09748.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like AA_permease_2 PF13520.6 OAG09750.1 - 4.1e-86 289.4 26.5 5.2e-86 289.1 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease Ni_hydr_CYTB PF01292.20 OAG09750.1 - 2.3 7.8 9.9 0.61 9.7 1.9 2.7 2 2 0 2 2 2 0 Prokaryotic cytochrome b561 DUF1295 PF06966.12 OAG09751.1 - 4.3e-32 111.5 0.6 5.7e-32 111.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OAG09751.1 - 0.00011 22.6 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 OAG09751.1 - 0.0021 16.9 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 OAG09751.1 - 0.0034 17.4 0.1 0.0093 16.0 0.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OAG09751.1 - 0.066 13.6 0.2 0.15 12.4 0.2 1.7 1 1 0 1 1 1 0 Phospholipid methyltransferase GST_N PF02798.20 OAG09752.1 - 3.6e-08 33.6 0.0 6.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG09752.1 - 4.2e-06 27.1 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG09752.1 - 5.9e-06 26.4 0.2 1.3e-05 25.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG09752.1 - 5.9e-06 26.4 0.4 1.5e-05 25.1 0.1 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG09752.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG09752.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LPMO_10 PF03067.15 OAG09753.1 - 0.11 13.1 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading OmpH PF03938.14 OAG09753.1 - 0.16 12.3 8.1 0.24 11.7 8.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ligase_CoA PF00549.19 OAG09754.1 - 8.8e-36 123.0 0.1 1.2e-16 60.8 0.0 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 OAG09754.1 - 1.2e-21 77.2 3.3 2.2e-21 76.3 1.0 2.5 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 OAG09754.1 - 1.5e-09 37.8 0.0 1.4e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 OAG09754.1 - 0.026 14.1 0.0 0.089 12.3 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain KilA-N PF04383.13 OAG09755.1 - 0.0096 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain tRNA_int_end_N2 PF12928.7 OAG09755.1 - 0.041 14.1 0.3 0.097 12.9 0.3 1.6 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Dppa2_A PF14049.6 OAG09755.1 - 0.047 13.8 1.2 0.047 13.8 1.2 1.9 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates Rho_GDI PF02115.17 OAG09757.1 - 1.5e-61 207.6 0.4 1.6e-61 207.4 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PSY3 PF16836.5 OAG09758.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Shu complex component Psy3, DNA-binding description PAXNEB PF05625.11 OAG09758.1 - 0.17 11.0 0.7 0.28 10.3 0.7 1.3 1 0 0 1 1 1 0 PAXNEB protein Adaptin_N PF01602.20 OAG09759.1 - 1.5e-97 327.4 0.0 1.9e-97 327.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG09759.1 - 2.2e-15 57.0 0.0 2.8e-14 53.5 0.0 2.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG09759.1 - 1.2e-05 25.6 5.1 0.0056 17.1 0.0 4.9 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 OAG09759.1 - 5.8e-05 23.0 2.6 8.1 7.0 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat EH_Signature PF15611.6 OAG09759.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 EH_Signature domain Nbs1_C PF08599.10 OAG09759.1 - 1.7 8.9 3.9 4.1 7.6 3.9 1.6 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 APH PF01636.23 OAG09760.1 - 4.3e-08 33.4 0.0 4.9e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_72 PF03198.14 OAG09761.1 - 1.6e-115 385.7 1.9 2e-115 385.4 1.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 OAG09761.1 - 0.00027 20.5 0.4 0.0012 18.4 0.4 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TAP42 PF04177.12 OAG09761.1 - 0.27 10.3 0.0 0.39 9.8 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family Sec7 PF01369.20 OAG09762.1 - 1e-60 204.5 0.0 1.7e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAG09762.1 - 9.8e-19 67.8 0.0 1.6e-17 63.8 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SipA_VBS PF17985.1 OAG09762.1 - 0.054 13.4 0.1 0.2 11.6 0.1 2.1 1 0 0 1 1 1 0 SipA vinculin binding site SPEG_u2 PF16650.5 OAG09762.1 - 0.059 13.6 0.3 0.27 11.4 0.3 2.2 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein Anp1 PF03452.14 OAG09763.1 - 3.2e-113 377.5 1.8 3.9e-113 377.2 0.0 1.9 2 0 0 2 2 2 1 Anp1 Glyco_tranf_2_4 PF13704.6 OAG09763.1 - 0.11 13.0 0.0 0.44 11.1 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 Hid1 PF12722.7 OAG09763.1 - 1.6 6.7 12.3 2.3 6.2 12.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Smg8_Smg9 PF10220.9 OAG09763.1 - 2.6 6.2 15.0 3.3 5.9 15.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 TssC PF17541.2 OAG09763.1 - 3.1 6.5 11.3 4.7 5.9 11.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB DDHD PF02862.17 OAG09763.1 - 4.6 7.3 8.9 10 6.2 8.9 1.6 1 0 0 1 1 1 0 DDHD domain AAA_23 PF13476.6 OAG09763.1 - 5.5 7.4 19.5 2.2 8.7 16.3 1.8 2 0 0 2 2 2 0 AAA domain RNase_PH PF01138.21 OAG09764.1 - 7e-25 88.0 0.0 1.1e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Arb1 PF09692.10 OAG09765.1 - 2.1e-124 415.8 0.0 2.6e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.17 OAG09765.1 - 6.8e-15 54.9 0.0 4.1e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 La domain DUF3807 PF12720.7 OAG09766.1 - 0.0053 17.0 6.9 0.0053 17.0 6.9 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3807) SR-25 PF10500.9 OAG09766.1 - 0.0055 16.3 27.8 0.014 15.1 27.8 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4604 PF15377.6 OAG09766.1 - 0.0058 17.1 14.5 0.014 15.9 14.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) AP3D1 PF06375.11 OAG09766.1 - 0.0093 16.2 16.7 0.0093 16.2 16.7 2.2 2 0 0 2 2 2 1 AP-3 complex subunit delta-1 MecA PF05389.12 OAG09766.1 - 0.019 14.6 3.8 0.033 13.8 3.8 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Connexin PF00029.19 OAG09766.1 - 0.052 13.3 4.1 0.087 12.6 4.1 1.3 1 0 0 1 1 1 0 Connexin Jak1_Phl PF17887.1 OAG09766.1 - 0.24 11.4 6.6 0.48 10.4 6.6 1.5 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain AAA_11 PF13086.6 OAG09766.1 - 0.24 11.2 7.2 0.48 10.2 7.2 1.5 1 0 0 1 1 1 0 AAA domain CPSF100_C PF13299.6 OAG09766.1 - 0.24 11.6 7.2 0.38 10.9 2.7 2.8 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF1764 PF08576.10 OAG09766.1 - 0.45 11.4 19.2 2 9.3 15.5 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) HA2 PF04408.23 OAG09766.1 - 0.56 10.5 3.2 1.6 9.1 3.2 1.7 1 0 0 1 1 1 0 Helicase associated domain (HA2) EIIBC-GUT_N PF03612.14 OAG09766.1 - 0.56 9.9 5.3 1.1 9.0 5.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GAGA_bind PF06217.12 OAG09766.1 - 1.2 9.4 15.0 0.1 12.9 9.8 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family OATP PF03137.20 OAG09766.1 - 1.3 7.2 4.9 0.8 7.9 2.0 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sec62 PF03839.16 OAG09766.1 - 2.5 7.5 14.1 4.5 6.7 14.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4578 PF15147.6 OAG09766.1 - 2.8 8.8 12.5 29 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4578) TMEM214 PF10151.9 OAG09766.1 - 3.3 6.0 12.5 5.8 5.2 12.5 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator EMC3_TMCO1 PF01956.16 OAG09766.1 - 5.5 6.7 5.3 9.8 5.9 5.3 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like YL1 PF05764.13 OAG09766.1 - 6.4 6.8 22.9 1.2 9.2 17.6 2.1 2 0 0 2 2 2 0 YL1 nuclear protein DUF1387 PF07139.11 OAG09766.1 - 8.3 6.0 22.6 15 5.2 22.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) TPR_10 PF13374.6 OAG09767.1 - 2.5e-12 46.3 0.0 3.6e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG09767.1 - 6.3e-10 39.2 0.0 4.4e-06 26.9 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG09767.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat HET PF06985.11 OAG09768.1 - 4.2e-10 40.2 9.6 1.6e-09 38.2 3.6 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 OAG09768.1 - 0.0002 21.8 0.6 0.0019 18.6 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain EGF_3 PF12947.7 OAG09769.1 - 0.0052 17.0 0.3 0.011 15.9 0.3 1.5 1 0 0 1 1 1 1 EGF domain EGF PF00008.27 OAG09769.1 - 0.077 13.3 0.5 0.15 12.4 0.5 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.15 OAG09769.1 - 0.16 12.2 1.7 0.25 11.6 0.8 1.8 2 0 0 2 2 2 0 Calcium-binding EGF domain Peptidase_S9 PF00326.21 OAG09770.1 - 3.2e-48 164.0 0.2 4.7e-48 163.5 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OAG09770.1 - 0.0034 17.3 4.0 0.092 12.7 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DIPSY PF11763.8 OAG09770.1 - 0.045 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Lipoprotein_15 PF03640.15 OAG09770.1 - 0.087 12.4 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Secreted repeat of unknown function PTR2 PF00854.21 OAG09772.1 - 3.5e-79 266.5 8.6 4.6e-79 266.1 8.6 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG09772.1 - 4.6e-09 35.7 15.4 4.2e-08 32.5 14.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 OAG09772.1 - 4.8 6.8 8.6 0.72 9.5 0.2 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) PAN_4 PF14295.6 OAG09773.1 - 0.0022 17.9 1.7 0.0038 17.1 0.7 1.9 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 OAG09774.1 - 6.7e-05 22.7 2.2 0.00015 21.6 2.2 1.6 1 0 0 1 1 1 1 PAN domain Zn_clus PF00172.18 OAG09776.1 - 0.005 16.9 12.6 0.012 15.7 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.23 OAG09777.1 - 2.5e-19 69.7 17.6 3e-19 69.5 17.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3273 PF11677.8 OAG09777.1 - 1.7 7.9 6.9 0.35 10.1 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3273) Lactonase PF10282.9 OAG09778.1 - 4.7e-21 75.4 1.5 6e-19 68.5 0.9 2.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Sugar_tr PF00083.24 OAG09779.1 - 2.5e-27 95.9 16.9 2.7e-27 95.7 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3792 PF12670.7 OAG09779.1 - 0.8 9.9 11.6 0.64 10.2 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Bac_rhamnosid6H PF17389.2 OAG09781.1 - 1.6e-13 50.7 1.5 2.1e-13 50.3 1.5 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 OAG09781.1 - 0.0012 17.6 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid PF05592.11 OAG09781.1 - 0.2 11.7 0.0 0.51 10.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Glyco_hydro_79C PF16862.5 OAG09782.1 - 1.1e-14 55.2 0.0 2.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Sugar_tr PF00083.24 OAG09783.1 - 2.5e-76 257.4 23.1 3.1e-76 257.1 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG09783.1 - 8.7e-30 103.8 24.4 5.9e-27 94.5 17.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG09783.1 - 0.00011 21.6 2.1 0.00011 21.6 2.1 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAG09783.1 - 0.00068 18.2 1.2 0.001 17.6 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 OAG09783.1 - 0.0007 18.3 3.1 0.0007 18.3 3.1 3.2 2 2 1 3 3 3 3 MFS/sugar transport protein YrhK PF14145.6 OAG09783.1 - 0.0068 16.3 1.6 0.0068 16.3 1.6 2.8 2 0 0 2 2 2 1 YrhK-like protein DAO PF01266.24 OAG09784.1 - 9.8e-34 117.5 0.0 1.3e-33 117.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG09784.1 - 2.7e-06 27.5 0.0 7.6e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 OAG09784.1 - 0.00013 21.5 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAG09784.1 - 0.0077 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG09784.1 - 0.014 14.7 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAG09784.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 OAG09784.1 - 0.047 12.9 0.0 0.1 11.8 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG09784.1 - 0.051 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 OAG09784.1 - 0.059 12.2 0.0 0.14 11.0 0.0 1.5 1 1 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG09784.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 OAG09784.1 - 0.15 12.0 0.0 0.38 10.6 0.0 1.7 1 1 0 1 1 1 0 KR domain HET PF06985.11 OAG09785.1 - 9.5e-26 90.9 0.1 1.7e-25 90.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_92 PF07971.12 OAG09786.1 - 1.9e-142 475.5 1.1 2.3e-142 475.2 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG09786.1 - 4.5e-55 187.1 2.7 4.5e-55 187.1 2.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain AAA_6 PF12774.7 OAG09787.1 - 1.2e-126 422.1 1.0 7.5e-126 419.5 0.0 3.0 4 0 0 4 4 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 OAG09787.1 - 5.9e-123 411.5 4.4 5.9e-123 411.5 4.4 5.1 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OAG09787.1 - 8e-116 387.4 6.9 8e-116 387.4 6.9 6.1 5 2 1 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 OAG09787.1 - 1.2e-73 246.8 1.9 1.2e-73 246.8 1.9 3.8 3 1 1 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 OAG09787.1 - 9.4e-68 228.3 0.0 1.6e-66 224.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OAG09787.1 - 2.1e-41 141.4 0.1 1e-35 122.9 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 OAG09787.1 - 1.9e-40 139.0 10.7 1.9e-40 139.0 10.7 2.3 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OAG09787.1 - 3e-32 111.7 0.0 7.8e-32 110.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OAG09787.1 - 2.8e-31 108.4 0.0 5.2e-12 45.9 0.0 6.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 OAG09787.1 - 4.8e-29 100.9 0.0 4.9e-27 94.4 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OAG09787.1 - 1.6e-18 67.1 0.8 9.8e-18 64.5 0.2 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 OAG09787.1 - 6e-13 49.4 0.0 0.0034 17.8 0.0 5.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG09787.1 - 2.4e-12 47.3 7.8 0.01 16.1 0.0 7.5 7 1 0 7 7 6 3 AAA domain AAA_16 PF13191.6 OAG09787.1 - 5.8e-10 39.8 7.1 1.8 8.9 0.0 8.9 9 0 0 9 9 7 1 AAA ATPase domain AAA_18 PF13238.6 OAG09787.1 - 5.3e-09 36.7 0.3 0.1 13.2 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 OAG09787.1 - 6.3e-08 32.9 8.2 0.27 11.4 0.0 5.9 6 0 0 6 6 4 3 AAA domain T2SSE PF00437.20 OAG09787.1 - 1.1e-06 27.9 0.0 0.018 14.1 0.0 3.9 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 OAG09787.1 - 4.5e-06 26.8 0.0 0.00046 20.4 0.0 3.2 2 0 0 2 2 2 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 OAG09787.1 - 5.8e-06 25.8 0.0 0.22 10.8 0.1 3.9 3 0 0 3 3 3 2 FtsK/SpoIIIE family ABC_tran PF00005.27 OAG09787.1 - 1.2e-05 25.8 2.5 4.8 7.7 0.0 6.1 5 0 0 5 5 4 1 ABC transporter AAA_29 PF13555.6 OAG09787.1 - 4.2e-05 23.2 0.3 2.3 8.0 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OAG09787.1 - 5.7e-05 22.6 1.3 0.53 9.6 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAG09787.1 - 0.00067 19.4 0.1 0.42 10.3 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein BRE1 PF08647.11 OAG09787.1 - 0.00069 19.6 4.9 0.00069 19.6 4.9 5.8 5 1 1 6 6 3 1 BRE1 E3 ubiquitin ligase AAA_24 PF13479.6 OAG09787.1 - 0.0023 17.7 7.2 32 4.2 0.0 6.2 6 0 0 6 6 6 0 AAA domain AAA_25 PF13481.6 OAG09787.1 - 0.0026 17.4 0.0 0.15 11.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAG09787.1 - 0.0082 16.5 0.1 24 5.4 0.0 4.6 4 0 0 4 4 4 0 RNA helicase AAA_19 PF13245.6 OAG09787.1 - 0.0095 16.3 7.9 0.19 12.1 0.0 5.1 6 0 0 6 6 4 1 AAA domain AAA_30 PF13604.6 OAG09787.1 - 0.01 15.5 3.6 47 3.6 0.2 5.1 6 0 0 6 6 4 0 AAA domain Rad17 PF03215.15 OAG09787.1 - 0.13 12.2 2.5 6.2 6.7 0.0 4.0 5 0 0 5 5 4 0 Rad17 P-loop domain RuvB_N PF05496.12 OAG09787.1 - 0.14 11.9 0.2 4.9 6.9 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain G-gamma PF00631.22 OAG09787.1 - 0.25 11.4 2.5 8.3 6.5 0.0 3.7 3 0 0 3 3 2 0 GGL domain MbeB_N PF04837.12 OAG09787.1 - 0.81 10.0 5.9 2.3 8.6 0.1 4.1 3 0 0 3 3 3 0 MbeB-like, N-term conserved region NACHT PF05729.12 OAG09787.1 - 4.1 7.3 7.4 31 4.4 0.0 4.3 4 0 0 4 4 3 0 NACHT domain DUF4482 PF14818.6 OAG09787.1 - 7.4 7.4 14.3 96 3.8 10.1 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) Voltage_CLC PF00654.20 OAG09788.1 - 4.2e-89 299.2 23.0 4.2e-89 299.2 23.0 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAG09788.1 - 1.4e-09 38.2 0.0 0.00059 20.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain Peptidase_S10 PF00450.22 OAG09789.1 - 3.2e-98 329.9 0.0 3.9e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4038 PF13204.6 OAG09790.1 - 2.4e-52 178.5 0.0 3e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) CBFD_NFYB_HMF PF00808.23 OAG09791.1 - 1.5e-10 41.2 0.3 2.9e-10 40.3 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG09791.1 - 0.07 13.5 0.7 0.11 12.9 0.4 1.5 1 1 1 2 2 2 0 Core histone H2A/H2B/H3/H4 Macro PF01661.21 OAG09792.1 - 3.5e-18 65.8 0.0 4.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Macro domain Rieske PF00355.26 OAG09793.1 - 5.6e-11 42.2 0.0 1.1e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 OAG09793.1 - 1.6e-07 31.7 0.8 2.7e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region BCIP PF13862.6 OAG09794.1 - 3.4e-70 236.0 0.0 4.4e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GMP_synt_C PF00958.22 OAG09795.1 - 1.3e-42 143.7 0.0 2.6e-42 142.8 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OAG09795.1 - 1e-35 123.2 0.0 1.7e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 OAG09795.1 - 1.9e-10 40.3 0.1 7e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 OAG09795.1 - 1.2e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 OAG09795.1 - 0.00065 19.3 0.0 0.0017 17.9 0.0 1.6 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OAG09795.1 - 0.0038 16.1 0.1 0.0097 14.7 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase Arginosuc_synth PF00764.19 OAG09795.1 - 0.022 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 OAG09795.1 - 0.035 13.7 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) EHN PF06441.12 OAG09796.1 - 1.3e-24 86.6 0.4 2.9e-24 85.5 0.4 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG09796.1 - 1.8e-06 27.8 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.25 OAG09798.1 - 7.5e-53 178.9 0.1 9.9e-53 178.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG09798.1 - 3.5e-34 118.4 0.1 4.4e-34 118.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG09798.1 - 6.9e-12 45.6 0.0 1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG09798.1 - 0.00021 21.5 0.1 0.0004 20.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 OAG09798.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 OAG09798.1 - 0.037 13.2 0.2 0.07 12.2 0.2 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 OAG09798.1 - 0.13 11.6 3.0 0.29 10.5 0.0 2.8 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Terpene_synth_C PF03936.16 OAG09799.1 - 0.0024 17.3 0.1 0.01 15.2 0.1 1.9 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain YqzH PF14164.6 OAG09799.1 - 0.18 11.9 0.0 0.48 10.5 0.0 1.8 1 0 0 1 1 1 0 YqzH-like protein p450 PF00067.22 OAG09800.1 - 1.4e-43 149.3 0.0 7.5e-43 146.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_15 PF00723.21 OAG09801.1 - 1.4e-69 235.0 0.0 1.6e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Zn_clus PF00172.18 OAG09802.1 - 1.2e-05 25.4 10.4 2.2e-05 24.5 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF350 PF03994.14 OAG09804.1 - 0.014 15.5 2.5 0.076 13.2 2.5 2.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) DUF2615 PF11027.8 OAG09804.1 - 0.093 12.9 0.2 0.95 9.6 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) FA_desaturase PF00487.24 OAG09804.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.7 2 2 1 3 3 3 0 Fatty acid desaturase PHO4 PF01384.20 OAG09804.1 - 0.12 11.4 3.3 0.1 11.7 2.1 1.5 1 1 0 1 1 1 0 Phosphate transporter family DUF2070 PF09843.9 OAG09804.1 - 0.98 7.6 6.0 1.2 7.3 6.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CbtA PF09490.10 OAG09804.1 - 1.2 8.9 6.2 0.13 12.0 0.5 2.2 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) PBP1_TM PF14812.6 OAG09805.1 - 0.034 14.5 16.0 0.13 12.6 2.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 OAG09806.1 - 2.9e-05 23.3 0.2 5.7e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09806.1 - 0.013 15.6 0.6 0.024 14.7 0.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphodiest PF01663.22 OAG09807.1 - 5.2e-31 108.5 0.0 8.3e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pro-kuma_activ PF09286.11 OAG09808.1 - 6.3e-33 114.1 1.0 7e-31 107.4 0.2 2.4 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG09808.1 - 4.4e-06 26.2 5.6 8.6e-06 25.2 5.6 1.4 1 0 0 1 1 1 1 Subtilase family FMO-like PF00743.19 OAG09809.1 - 2e-21 76.0 1.4 1.2e-17 63.6 0.2 2.9 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG09809.1 - 1.5e-11 44.4 0.0 4.2e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG09809.1 - 1.2e-09 37.8 0.0 1.6e-06 27.5 0.0 3.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG09809.1 - 1.3e-09 37.7 0.0 6.8e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG09809.1 - 2.3e-09 37.0 0.0 6.8e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG09809.1 - 0.0007 19.6 2.5 0.25 11.3 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG09809.1 - 0.0013 18.4 0.4 0.3 10.6 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG09809.1 - 0.0035 16.6 0.4 0.032 13.5 0.0 2.3 3 0 0 3 3 3 1 Thi4 family Malic_M PF03949.15 OAG09809.1 - 0.075 12.3 0.0 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain GIDA PF01134.22 OAG09809.1 - 0.21 10.6 0.3 15 4.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Fe-ADH PF00465.19 OAG09810.1 - 1.6e-66 224.6 0.0 2.1e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG09810.1 - 2.3e-05 24.2 0.1 0.011 15.4 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF3176 PF11374.8 OAG09811.1 - 4.7e-16 58.9 0.3 4.7e-16 58.9 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Gly-zipper_Omp PF13488.6 OAG09811.1 - 0.007 16.3 4.3 0.007 16.3 4.3 2.1 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 OAG09811.1 - 0.013 15.3 4.5 0.037 13.8 4.5 1.8 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF4996 PF16387.5 OAG09811.1 - 0.038 14.5 0.1 0.07 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function Rick_17kDa_Anti PF05433.15 OAG09811.1 - 2.5 8.0 12.6 0.078 12.9 6.1 1.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain DJ-1_PfpI PF01965.24 OAG09812.1 - 3.2e-12 46.6 0.0 8.1e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG09812.1 - 2e-07 30.9 0.0 7.9e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like MFS_1 PF07690.16 OAG09813.1 - 5.2e-31 107.9 24.7 5.2e-31 107.9 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 OAG09813.1 - 1.6 8.8 9.9 5.8 7.0 0.1 3.0 2 0 0 2 2 2 0 Glycine zipper KASH_CCD PF14662.6 OAG09814.1 - 0.00062 19.7 4.7 0.001 18.9 4.7 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH EzrA PF06160.12 OAG09814.1 - 0.001 17.3 3.7 0.0014 16.9 3.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Cep57_CLD_2 PF14197.6 OAG09814.1 - 0.0012 18.8 6.1 0.0026 17.8 6.1 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 ERM PF00769.19 OAG09814.1 - 0.0022 17.8 4.9 0.004 17.0 4.9 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family ADIP PF11559.8 OAG09814.1 - 0.0028 17.8 5.4 0.0055 16.8 5.4 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 OAG09814.1 - 0.0029 17.1 2.0 0.0044 16.5 2.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF4686 PF15742.5 OAG09814.1 - 0.0032 16.7 2.2 0.0047 16.1 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) DUF4472 PF14739.6 OAG09814.1 - 0.0036 18.0 6.8 0.015 16.0 5.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4472) GAS PF13851.6 OAG09814.1 - 0.0037 16.7 6.9 0.0049 16.3 5.9 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF2353 PF09789.9 OAG09814.1 - 0.0066 15.9 2.4 0.01 15.2 2.4 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 OAG09814.1 - 0.0078 16.2 2.3 0.014 15.5 2.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OAG09814.1 - 0.0099 16.4 4.1 0.0099 16.4 4.1 1.5 2 0 0 2 2 1 1 Fez1 HOOK PF05622.12 OAG09814.1 - 0.017 13.3 3.0 0.024 12.8 3.0 1.1 1 0 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 OAG09814.1 - 0.018 15.1 5.3 0.035 14.2 5.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 OAG09814.1 - 0.02 15.4 5.1 0.036 14.6 5.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TACC_C PF05010.14 OAG09814.1 - 0.022 14.5 1.9 0.035 13.9 1.9 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Seryl_tRNA_N PF02403.22 OAG09814.1 - 0.024 14.9 4.4 0.046 13.9 4.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MscS_porin PF12795.7 OAG09814.1 - 0.024 14.2 3.6 0.035 13.6 3.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF812 PF05667.11 OAG09814.1 - 0.024 13.6 1.9 0.031 13.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 OAG09814.1 - 0.027 13.4 4.1 0.045 12.6 4.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin PF00261.20 OAG09814.1 - 0.029 13.8 6.1 0.043 13.2 6.1 1.2 1 0 0 1 1 1 0 Tropomyosin UPF0242 PF06785.11 OAG09814.1 - 0.03 14.4 2.0 0.052 13.7 2.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BST2 PF16716.5 OAG09814.1 - 0.032 14.8 1.9 0.055 14.1 1.9 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Tropomyosin_1 PF12718.7 OAG09814.1 - 0.033 14.3 4.7 0.056 13.6 4.2 1.6 1 1 0 1 1 1 0 Tropomyosin like PI3K_P85_iSH2 PF16454.5 OAG09814.1 - 0.035 13.7 3.8 0.058 13.0 3.8 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Lectin_N PF03954.14 OAG09814.1 - 0.035 13.8 0.8 0.076 12.8 0.8 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain OmpH PF03938.14 OAG09814.1 - 0.036 14.4 2.0 0.063 13.6 2.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.8 OAG09814.1 - 0.04 14.2 6.9 0.62 10.3 0.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 OAG09814.1 - 0.043 13.9 2.9 0.59 10.3 1.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor DUF745 PF05335.13 OAG09814.1 - 0.069 12.9 2.3 0.11 12.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DMPK_coil PF08826.10 OAG09814.1 - 0.078 13.1 8.8 7.2 6.8 0.0 3.4 1 1 2 3 3 3 0 DMPK coiled coil domain like YabA PF06156.13 OAG09814.1 - 0.08 13.6 3.8 0.26 11.9 3.7 1.8 1 1 1 2 2 2 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 OAG09814.1 - 0.12 11.9 3.4 0.19 11.3 3.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 BLOC1_2 PF10046.9 OAG09814.1 - 0.13 12.6 1.2 0.74 10.1 0.3 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Troponin PF00992.20 OAG09814.1 - 0.13 12.6 4.4 0.31 11.3 4.4 1.6 1 0 0 1 1 1 0 Troponin DUF4618 PF15397.6 OAG09814.1 - 0.14 11.5 2.4 0.22 10.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ATG16 PF08614.11 OAG09814.1 - 0.15 12.3 12.9 0.34 11.1 12.9 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 OAG09814.1 - 0.15 12.1 1.4 0.28 11.2 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HemX PF04375.14 OAG09814.1 - 0.23 10.7 2.5 0.34 10.2 2.5 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DivIC PF04977.15 OAG09814.1 - 0.33 10.8 6.0 1.9 8.3 0.2 2.3 1 1 1 2 2 2 0 Septum formation initiator TMPIT PF07851.13 OAG09814.1 - 0.37 10.0 1.2 0.54 9.4 1.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 OAG09814.1 - 0.49 8.3 1.2 0.69 7.8 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.6 OAG09814.1 - 0.5 10.1 3.7 0.74 9.5 3.7 1.2 1 0 0 1 1 1 0 AAA domain FemAB PF02388.16 OAG09814.1 - 0.56 9.0 2.9 0.88 8.4 2.6 1.4 2 0 0 2 2 1 0 FemAB family FUSC PF04632.12 OAG09814.1 - 0.57 8.6 4.6 0.76 8.2 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.14 OAG09814.1 - 0.66 9.8 5.2 1.1 9.0 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.11 OAG09814.1 - 0.68 8.7 10.6 1.4 7.7 10.6 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Ax_dynein_light PF10211.9 OAG09814.1 - 1.9 8.4 6.4 7.3 6.5 6.3 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain DHR10 PF18595.1 OAG09814.1 - 2.6 8.1 11.8 9.5 6.3 11.8 1.9 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain ZapB PF06005.12 OAG09814.1 - 2.7 8.5 7.9 1.4e+02 3.0 7.9 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Prefoldin_2 PF01920.20 OAG09814.1 - 3.2 7.8 6.3 20 5.2 5.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit Spc24 PF08286.11 OAG09814.1 - 7.4 6.9 5.8 84 3.5 5.8 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Glyco_hydro_127 PF07944.12 OAG09815.1 - 6.6e-95 318.6 0.0 1.5e-94 317.4 0.0 1.6 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 GH131_N PF18271.1 OAG09816.1 - 4.6e-64 216.6 1.7 4.6e-64 216.6 1.7 1.6 2 0 0 2 2 2 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 OAG09816.1 - 0.016 15.1 1.2 0.067 13.0 1.2 1.8 1 1 0 1 1 1 0 Polysaccharide lyase SOG2 PF10428.9 OAG09816.1 - 0.15 11.2 8.9 0.16 11.1 8.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Cutinase PF01083.22 OAG09817.1 - 8e-23 81.3 0.0 6.6e-22 78.3 0.1 1.9 2 0 0 2 2 2 1 Cutinase VirJ PF06057.11 OAG09817.1 - 0.00088 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Hydrolase_4 PF12146.8 OAG09817.1 - 0.0046 16.2 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PE-PPE PF08237.11 OAG09817.1 - 0.031 13.8 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Thioesterase PF00975.20 OAG09817.1 - 0.21 11.7 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain TF_AP-2 PF03299.14 OAG09818.1 - 0.058 13.4 0.1 0.058 13.4 0.1 2.0 2 0 0 2 2 2 0 Transcription factor AP-2 HrpJ PF07201.11 OAG09818.1 - 1.5 9.1 11.1 0.79 10.0 0.6 2.4 2 0 0 2 2 2 0 HrpJ-like domain eIF-3c_N PF05470.12 OAG09818.1 - 2.1 6.5 9.8 2.9 6.1 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RNA_polI_A34 PF08208.11 OAG09818.1 - 3 7.9 19.2 5.5 7.0 4.8 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 U3_snoRNA_assoc PF08297.11 OAG09818.1 - 5.3 7.8 13.0 5.3 7.8 2.5 2.6 2 0 0 2 2 2 0 U3 snoRNA associated EMC3_TMCO1 PF01956.16 OAG09818.1 - 7.2 6.3 6.7 6.3 6.5 0.5 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like LsmAD PF06741.13 OAG09818.1 - 9.2 6.9 13.0 0.3 11.7 2.0 3.0 3 0 0 3 3 3 0 LsmAD domain Lipoxygenase PF00305.19 OAG09819.1 - 4.2e-21 75.1 0.0 6.5e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase PRMT5 PF05185.16 OAG09819.1 - 0.31 10.9 0.8 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase AMP-binding PF00501.28 OAG09820.1 - 4.6e-71 239.6 0.0 6.2e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAG09820.1 - 2.8e-07 30.8 0.1 7.1e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Aa_trans PF01490.18 OAG09821.1 - 1.9e-24 86.1 37.0 2.3e-24 85.9 37.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4396 PF14342.6 OAG09822.1 - 1.5e-44 151.8 6.9 1.5e-44 151.8 6.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4396) PPO1_DWL PF12142.8 OAG09822.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Polyphenol oxidase middle domain TRI12 PF06609.13 OAG09823.1 - 5e-63 213.5 22.0 6.2e-63 213.2 22.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG09823.1 - 2e-26 92.7 61.1 2.2e-26 92.6 55.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG09823.1 - 6.6e-13 48.3 6.3 6.6e-13 48.3 6.3 3.5 3 1 0 4 4 4 1 Sugar (and other) transporter Wzz PF02706.15 OAG09823.1 - 0.17 12.2 9.4 1.2 9.5 0.3 3.5 3 0 0 3 3 3 0 Chain length determinant protein DUF4220 PF13968.6 OAG09823.1 - 0.27 10.6 1.4 1.6 8.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) p450 PF00067.22 OAG09824.1 - 8.6e-76 255.5 0.0 1e-75 255.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TAXi_C PF14541.6 OAG09824.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF3425 PF11905.8 OAG09825.1 - 6.4e-16 58.5 0.8 1e-15 57.8 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PAN_1 PF00024.26 OAG09826.1 - 7.3e-09 35.5 11.0 0.00017 21.5 0.6 3.1 3 0 0 3 3 3 2 PAN domain PAN_4 PF14295.6 OAG09826.1 - 1.9e-08 34.1 4.3 0.0025 17.7 0.6 2.5 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 OAG09826.1 - 0.0046 17.0 0.9 0.0046 17.0 0.9 3.4 3 1 0 3 3 3 2 PAN-like domain DUF1387 PF07139.11 OAG09826.1 - 0.1 12.3 11.9 0.13 12.0 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PAN_3 PF08277.12 OAG09826.1 - 0.12 12.1 9.0 0.3 10.9 0.2 2.9 3 0 0 3 3 2 0 PAN-like domain TFIIA PF03153.13 OAG09826.1 - 0.27 11.2 14.7 0.31 11.0 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MANEC PF07502.14 OAG09826.1 - 0.31 11.3 11.9 1 9.6 0.6 3.2 2 1 1 3 3 3 0 MANEC domain DUF966 PF06136.13 OAG09826.1 - 1.4 8.6 9.1 1.5 8.4 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.9 OAG09826.1 - 1.6 7.2 10.6 2 6.9 10.6 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 OAG09826.1 - 2.5 6.7 9.6 2.9 6.5 9.6 1.2 1 0 0 1 1 1 0 Hamartin protein SWI-SNF_Ssr4 PF08549.10 OAG09826.1 - 3.2 6.3 15.7 3.8 6.0 15.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RAP1 PF07218.11 OAG09826.1 - 7.7 4.7 12.6 11 4.2 12.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RR_TM4-6 PF06459.12 OAG09826.1 - 8.9 6.0 13.7 13 5.5 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OAG09826.1 - 9.2 4.9 12.1 12 4.5 12.1 1.1 1 0 0 1 1 1 0 Presenilin Thioredoxin PF00085.20 OAG09827.1 - 9.2e-08 32.0 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OAG09827.1 - 0.0029 17.7 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OAG09827.1 - 0.01 16.3 0.0 0.37 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain RSN1_7TM PF02714.15 OAG09828.1 - 1e-88 297.2 20.2 1e-88 297.2 20.2 2.5 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG09828.1 - 2.4e-44 150.8 2.7 2.4e-44 150.8 2.7 2.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG09828.1 - 3.2e-27 95.9 0.2 5.2e-27 95.2 0.2 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAG09828.1 - 3.3e-19 68.8 0.1 8.3e-19 67.6 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter S_4TM PF18159.1 OAG09828.1 - 5.9 6.1 6.9 0.73 9.1 1.2 2.4 2 1 1 3 3 3 0 SMODS-associating 4TM effector domain DUF4231 PF14015.6 OAG09829.1 - 2 8.9 8.4 31 5.1 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) Oxidored_q2 PF00420.24 OAG09829.1 - 8 6.1 14.7 10 5.8 0.2 3.6 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ammonium_transp PF00909.21 OAG09830.1 - 2.4e-110 369.0 26.9 2.7e-110 368.8 26.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3482 PF11981.8 OAG09830.1 - 1.4 8.3 3.4 2.1 7.6 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Zn_clus PF00172.18 OAG09831.1 - 7.2e-08 32.4 9.3 1.3e-07 31.7 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG09831.1 - 5.4e-05 22.2 0.1 8.8e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 OAG09832.1 - 1.4e-14 54.2 0.0 9.9e-14 51.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG09832.1 - 9.1e-12 45.2 0.2 2.1e-10 40.8 0.1 2.1 1 1 1 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG09832.1 - 1.1e-09 37.9 0.0 1.5e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG09832.1 - 1.6e-06 27.3 0.0 0.00018 20.6 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG09832.1 - 2.7e-05 23.5 0.3 5.4e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 OAG09832.1 - 6.6e-05 23.2 0.0 0.0002 21.6 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 OAG09832.1 - 0.00015 21.3 0.1 0.0013 18.2 0.0 2.2 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG09832.1 - 0.00022 20.9 0.0 0.00047 19.8 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.17 OAG09832.1 - 0.072 13.7 0.0 0.15 12.6 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pex2_Pex12 PF04757.14 OAG09833.1 - 5.7e-52 176.6 0.5 7e-52 176.2 0.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 OAG09833.1 - 0.00056 20.0 1.0 0.00092 19.3 1.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAG09833.1 - 0.0011 18.8 0.4 0.0017 18.2 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG09833.1 - 0.0019 18.0 0.6 0.0032 17.3 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG09833.1 - 0.0039 17.2 1.3 0.0068 16.4 1.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG09833.1 - 0.0044 16.9 0.5 0.0065 16.3 0.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG09833.1 - 0.058 13.7 1.4 0.095 13.1 1.4 1.3 1 0 0 1 1 1 0 Ring finger domain PQ-loop PF04193.14 OAG09834.1 - 3.9e-21 74.6 7.7 5.1e-12 45.4 0.9 3.9 4 1 0 4 4 4 2 PQ loop repeat DUF4153 PF13687.6 OAG09834.1 - 5.4e-05 22.9 6.6 5.4e-05 22.9 6.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4153) Nucleoside_tran PF01733.18 OAG09834.1 - 0.018 14.5 0.9 0.018 14.5 0.9 2.1 2 0 0 2 2 2 0 Nucleoside transporter Serinc PF03348.15 OAG09834.1 - 0.021 13.8 0.7 0.034 13.1 0.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) 7tm_1 PF00001.21 OAG09834.1 - 0.091 12.1 3.2 0.15 11.3 3.2 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Fig1 PF12351.8 OAG09834.1 - 0.46 10.4 4.5 0.7 9.8 2.1 2.3 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF2070 PF09843.9 OAG09834.1 - 0.5 8.6 10.6 0.7 8.1 10.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DHHC PF01529.20 OAG09834.1 - 9.3 6.4 10.9 0.55 10.3 2.7 2.4 2 1 1 3 3 3 0 DHHC palmitoyltransferase MatE PF01554.18 OAG09835.1 - 1e-62 210.6 24.2 4.6e-35 120.7 7.8 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAG09835.1 - 2.6e-07 30.8 6.2 2.6e-07 30.8 6.2 3.6 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Cupin_3 PF05899.12 OAG09836.1 - 3e-07 30.1 0.1 7.2e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OAG09836.1 - 0.001 18.7 0.2 0.0023 17.6 0.0 1.7 2 0 0 2 2 2 1 Cupin domain EutQ PF06249.12 OAG09836.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DUF4437 PF14499.6 OAG09836.1 - 0.016 14.4 0.1 0.067 12.3 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4437) F-box-like PF12937.7 OAG09837.1 - 8.5e-09 35.2 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG09837.1 - 1.4e-08 34.4 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 OAG09837.1 - 0.0077 16.1 15.1 0.41 10.7 1.0 3.7 3 0 0 3 3 3 3 Ubiquitin interaction motif F-box_5 PF18511.1 OAG09837.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box COX1 PF00115.20 OAG09837.1 - 0.34 9.7 0.2 0.67 8.7 0.2 1.4 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I NAAA-beta PF15508.6 OAG09838.1 - 4.8e-09 36.4 0.1 1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SLATT_2 PF18183.1 OAG09838.1 - 0.059 13.1 0.0 6.5 6.5 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 2 CBAH PF02275.18 OAG09838.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family RRM_1 PF00076.22 OAG09839.1 - 1.5e-21 76.0 4.4 3.4e-10 39.6 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG09839.1 - 0.00039 20.2 0.1 0.31 10.9 0.1 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Calcipressin PF04847.12 OAG09839.1 - 0.0028 17.4 1.4 0.039 13.7 0.0 2.3 2 1 0 2 2 2 1 Calcipressin RRM_5 PF13893.6 OAG09839.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAG09839.1 - 0.042 14.1 7.2 3.2 8.0 0.0 3.5 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 OAG09839.1 - 0.086 13.0 0.1 19 5.5 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif RRM_Rrp7 PF17799.1 OAG09839.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain ATP-synt_D PF01813.17 OAG09840.1 - 3.3e-71 239.2 2.1 4.4e-71 238.8 2.1 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 OAG09840.1 - 0.095 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Suf PF05843.14 OAG09841.1 - 3.8e-14 53.4 6.9 0.026 14.5 0.1 6.2 3 1 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAG09841.1 - 9.3e-12 44.7 16.3 2.7 9.0 0.0 11.2 10 2 2 12 12 11 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG09841.1 - 1.8e-05 24.1 6.1 0.074 12.2 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OAG09841.1 - 2.4e-05 24.3 11.9 0.92 9.5 0.0 6.9 6 1 2 8 8 8 2 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 OAG09841.1 - 9.2e-05 22.9 0.1 23 5.6 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 OAG09841.1 - 0.00014 21.1 9.9 0.0064 15.7 0.1 5.0 3 3 0 4 4 4 1 NRDE-2, necessary for RNA interference RPN7 PF10602.9 OAG09841.1 - 0.00024 20.8 0.1 0.0013 18.4 0.0 2.3 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 OAG09841.1 - 0.0016 18.4 10.0 0.1 12.7 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG09841.1 - 0.015 15.3 0.9 0.77 9.9 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat CKAP2_C PF15297.6 OAG09841.1 - 0.029 13.5 0.3 0.076 12.1 0.3 1.6 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus TPR_8 PF13181.6 OAG09841.1 - 0.051 13.8 13.6 0.81 10.1 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat YnfE PF17452.2 OAG09841.1 - 0.13 12.6 0.5 0.62 10.4 0.5 2.2 1 0 0 1 1 1 0 Uncharacterized YnfE-like TPR_17 PF13431.6 OAG09841.1 - 0.13 12.7 3.6 92 3.8 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG09841.1 - 0.19 11.6 6.0 1.2e+02 2.7 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG09841.1 - 0.49 11.1 7.3 98 3.9 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat HAT PF02184.16 OAG09841.1 - 2.5 8.2 9.0 4.1 7.5 0.1 5.3 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat MFS_1 PF07690.16 OAG09842.1 - 1.5e-33 116.2 21.9 3.9e-25 88.5 8.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG09842.1 - 0.00072 18.5 0.7 0.00072 18.5 0.7 1.7 2 0 0 2 2 2 1 MFS_1 like family VIT1 PF01988.19 OAG09842.1 - 0.035 14.0 0.3 0.14 12.0 0.1 2.0 1 1 1 2 2 2 0 VIT family Loricrin PF15847.5 OAG09843.1 - 0.19 10.8 4.0 0.14 11.2 0.6 1.9 2 0 0 2 2 2 0 Major keratinocyte cell envelope protein Gpr1_Fun34_YaaH PF01184.19 OAG09844.1 - 5.3e-29 101.3 22.9 6.7e-29 101.0 22.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family NUC153 PF08159.12 OAG09848.1 - 2.2e-14 52.9 1.5 2.2e-14 52.9 1.5 3.7 3 0 0 3 3 3 2 NUC153 domain Fmp27 PF10344.9 OAG09848.1 - 0.26 9.3 4.7 0.6 8.1 4.7 1.6 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 HET PF06985.11 OAG09850.1 - 1.2e-23 84.0 0.0 2.2e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 OAG09851.1 - 1.7e-14 55.0 4.3 2.7e-14 54.3 4.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG09851.1 - 4.5e-11 42.5 0.1 1.1e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG09851.1 - 2.1e-08 34.2 0.5 3.5e-08 33.4 0.5 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.18 OAG09851.1 - 0.0063 16.1 0.1 0.019 14.5 0.1 1.7 1 1 0 1 1 1 1 Lipase (class 2) DUF2974 PF11187.8 OAG09851.1 - 0.011 15.4 0.5 0.018 14.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 OAG09851.1 - 0.018 14.8 0.1 0.037 13.8 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein Abhydro_lipase PF04083.16 OAG09851.1 - 0.086 12.4 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region LCAT PF02450.15 OAG09851.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Peptidase_S9 PF00326.21 OAG09851.1 - 0.19 11.2 4.4 0.24 10.9 0.9 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pyr_redox_2 PF07992.14 OAG09852.1 - 1.8e-38 132.5 0.0 2.4e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG09852.1 - 4.6e-10 39.9 0.0 3.8e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 OAG09852.1 - 3.6e-06 26.1 0.1 1.2e-05 24.5 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG09852.1 - 0.00015 21.4 0.2 0.00052 19.7 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAG09852.1 - 0.0049 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAG09852.1 - 0.011 15.2 0.3 0.011 15.2 0.3 2.0 2 0 0 2 2 2 0 EF hand Pyr_redox_3 PF13738.6 OAG09852.1 - 0.27 10.4 0.4 1.8 7.7 0.6 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 OAG09853.1 - 6.3e-30 102.8 11.6 7.8e-06 26.5 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAG09853.1 - 2.4e-08 33.1 7.6 0.14 10.8 0.4 5.1 3 2 2 5 5 5 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAG09853.1 - 3e-06 27.4 0.2 1.6 9.1 0.0 4.9 2 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OAG09853.1 - 0.0021 18.1 0.1 0.04 13.9 0.0 3.1 4 1 0 4 4 3 1 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 OAG09853.1 - 0.014 14.8 0.3 0.12 11.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) APG6_N PF17675.1 OAG09853.1 - 0.051 14.1 1.8 0.1 13.1 1.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DinB_2 PF12867.7 OAG09853.1 - 0.082 13.4 0.3 17 5.9 0.0 2.8 2 0 0 2 2 2 0 DinB superfamily Rab5-bind PF09311.11 OAG09853.1 - 0.14 11.6 1.3 0.2 11.0 1.3 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Adeno_PV PF03910.13 OAG09853.1 - 0.16 10.6 0.4 0.32 9.7 0.4 1.4 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF1664 PF07889.12 OAG09853.1 - 0.17 11.9 1.0 0.37 10.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 OAG09853.1 - 0.23 11.7 1.0 0.44 10.8 1.0 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 Osmo_CC PF08946.10 OAG09853.1 - 0.51 10.6 4.7 4.4 7.6 0.9 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil CENP-F_leu_zip PF10473.9 OAG09853.1 - 0.64 10.0 5.2 1.1 9.2 5.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALG3 PF05208.13 OAG09855.1 - 8.6e-143 476.1 12.1 9.9e-143 475.9 12.1 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 OAG09856.1 - 6.2e-18 64.4 0.1 8.9e-18 63.9 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HAS-barrel PF09378.10 OAG09856.1 - 0.038 14.1 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 HAS barrel domain DUF1953 PF09196.10 OAG09856.1 - 0.074 12.9 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) Glyco_hyd_65N_2 PF14498.6 OAG09857.1 - 9.5e-50 169.6 0.0 1.4e-49 169.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain RNase_H2_suC PF08615.11 OAG09858.1 - 9.3e-30 103.7 0.0 1.2e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PAP2_3 PF14378.6 OAG09858.1 - 0.21 11.2 0.1 0.26 10.9 0.1 1.1 1 0 0 1 1 1 0 PAP2 superfamily Porin_1 PF00267.21 OAG09859.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Gram-negative porin CMAS PF02353.20 OAG09860.1 - 4.6e-67 226.2 0.0 2.2e-66 224.0 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAG09860.1 - 1.2e-10 42.0 0.0 2.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG09860.1 - 3.4e-10 40.4 0.0 6.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG09860.1 - 3.1e-07 30.4 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG09860.1 - 3.9e-06 26.7 0.0 6.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG09860.1 - 0.00011 22.9 0.0 0.00023 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 OAG09860.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 OAG09860.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 OAG09860.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase His_Phos_1 PF00300.22 OAG09861.1 - 1.4e-19 70.5 0.0 1.9e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DHHC PF01529.20 OAG09862.1 - 0.0098 16.0 3.2 0.0098 16.0 3.2 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase EVC2_like PF12297.8 OAG09862.1 - 0.34 9.6 0.8 0.46 9.1 0.0 1.5 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein bZIP_1 PF00170.21 OAG09863.1 - 0.46 10.6 5.3 0.95 9.6 5.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor Cnl2_NKP2 PF09447.10 OAG09864.1 - 0.11 12.7 0.3 0.21 11.8 0.3 1.6 1 1 0 1 1 1 0 Cnl2/NKP2 family protein MFS_1 PF07690.16 OAG09865.1 - 1.7e-33 116.0 58.9 9.9e-28 97.1 34.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 OAG09865.1 - 2.9 8.1 4.5 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Metallophos PF00149.28 OAG09866.1 - 2.1e-32 113.3 0.0 6e-23 82.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OAG09866.1 - 0.037 13.6 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 OAG09866.1 - 0.082 13.4 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 OAG09867.1 - 0.002 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 zf-C2H2 PF00096.26 OAG09868.1 - 5.5e-05 23.4 14.2 0.02 15.3 0.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG09868.1 - 0.0014 19.3 14.1 0.16 12.9 1.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-TRAF PF02176.18 OAG09868.1 - 0.0039 17.8 6.0 0.16 12.7 3.7 2.4 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 OAG09868.1 - 0.11 12.9 0.5 0.11 12.9 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OAG09868.1 - 0.5 10.2 11.6 0.6 9.9 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 OAG09868.1 - 0.98 10.1 4.7 52 4.6 0.1 3.3 1 1 2 3 3 3 0 FOXP coiled-coil domain adh_short PF00106.25 OAG09870.1 - 6.2e-27 94.3 0.0 8.5e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG09870.1 - 5.2e-20 72.0 0.0 7.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG09870.1 - 8.5e-07 29.1 0.2 4.3e-06 26.8 0.1 2.1 3 0 0 3 3 3 1 KR domain NAD_binding_10 PF13460.6 OAG09870.1 - 0.00074 19.4 0.1 0.0011 18.9 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Fibrillarin PF01269.17 OAG09870.1 - 0.0097 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin Lar_N PF09861.9 OAG09870.1 - 0.033 13.3 0.1 0.088 12.0 0.1 1.6 1 1 1 2 2 2 0 Lactate racemase N-terminal domain NmrA PF05368.13 OAG09870.1 - 0.092 12.3 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family VWA_CoxE PF05762.14 OAG09870.1 - 0.19 11.1 0.0 0.56 9.6 0.0 1.7 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Fungal_trans_2 PF11951.8 OAG09871.1 - 7.3e-28 97.4 0.0 1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09871.1 - 1.2e-08 34.9 7.8 2.1e-08 34.2 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_9 PF13527.7 OAG09873.1 - 4.8e-07 29.9 0.1 1.7e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG09873.1 - 6.3e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG09873.1 - 0.002 18.5 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG09873.1 - 0.0057 16.9 0.0 0.0095 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NUDIX PF00293.28 OAG09874.1 - 5e-26 91.3 0.0 7.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HMGL-like PF00682.19 OAG09875.1 - 1.3e-77 261.0 0.2 2.1e-77 260.3 0.2 1.4 1 0 0 1 1 1 1 HMGL-like GFA PF04828.14 OAG09876.1 - 1.9e-11 44.1 0.0 2.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 OAG09876.1 - 0.048 13.3 2.2 0.065 12.9 0.3 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain AGH PF17558.2 OAG09876.1 - 0.091 12.9 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Androgenic gland hormone zf-C3HC4_3 PF13920.6 OAG09877.1 - 2.8e-08 33.5 10.6 4.3e-08 32.9 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG09877.1 - 0.0044 16.8 10.2 0.0073 16.1 10.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PI3K_1B_p101 PF10486.9 OAG09877.1 - 0.099 10.4 0.5 0.14 9.9 0.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HicA_toxin PF07927.12 OAG09880.1 - 0.0018 18.3 0.1 0.0045 17.0 0.0 1.7 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, Fungal_trans PF04082.18 OAG09881.1 - 3.1e-40 137.9 0.0 4.8e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG09881.1 - 3.1e-09 36.8 8.4 7.5e-09 35.6 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.23 OAG09882.1 - 2.5e-20 72.5 0.3 4e-20 71.8 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG09882.1 - 1.7e-12 47.6 0.0 4e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 OAG09882.1 - 3.7e-06 26.8 4.2 7.5e-06 25.8 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG09882.1 - 0.00015 21.6 4.6 0.00032 20.5 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAG09882.1 - 0.0048 16.7 0.9 0.014 15.2 0.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG09882.1 - 0.0099 15.7 4.4 0.02 14.8 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG09882.1 - 0.095 12.7 2.0 0.23 11.5 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG09882.1 - 0.29 11.1 8.6 0.041 13.7 3.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG09882.1 - 0.97 9.3 4.9 0.3 10.9 1.5 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 OAG09882.1 - 2.8 8.1 7.3 42 4.4 7.4 2.8 1 1 0 1 1 1 0 FYVE zinc finger ArfGap PF01412.18 OAG09882.1 - 5.2 7.2 10.7 3.8 7.6 3.4 2.9 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf zf-C3HC4_4 PF15227.6 OAG09882.1 - 7.9 6.7 9.0 1.3 9.3 4.7 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Na_Ca_ex PF01699.24 OAG09883.1 - 1.3e-41 142.1 38.1 3.1e-22 79.1 15.0 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein ABA_GPCR PF12430.8 OAG09883.1 - 0.011 15.5 3.9 0.011 15.5 3.9 2.1 2 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor PAP2 PF01569.21 OAG09885.1 - 3.8e-18 65.6 5.0 9.2e-18 64.3 5.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OAG09885.1 - 0.44 10.2 11.0 0.016 14.9 4.4 2.1 2 1 0 2 2 2 0 PAP2 superfamily DUF2070 PF09843.9 OAG09885.1 - 0.5 8.6 3.3 0.79 7.9 3.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC2_membrane_5 PF13346.6 OAG09885.1 - 6.1 6.3 8.7 0.53 9.8 0.3 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Ras PF00071.22 OAG09886.1 - 1.1e-48 164.9 0.0 1.5e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG09886.1 - 1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG09886.1 - 6.3e-06 25.8 0.0 1.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 OAG09886.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DASH_Dad1 PF08649.10 OAG09887.1 - 1.1e-24 86.4 1.2 1.3e-24 86.1 1.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 OAG09887.1 - 0.046 13.7 0.6 0.053 13.5 0.6 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 tRNA_int_endo PF01974.17 OAG09888.1 - 3.1e-13 49.6 0.0 7e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain HTH_22 PF13309.6 OAG09888.1 - 0.073 13.2 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 HTH domain Transp_cyt_pur PF02133.15 OAG09889.1 - 5.3e-85 285.8 43.4 6.7e-85 285.5 43.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 OAG09890.1 - 5.9e-28 98.0 0.1 9.2e-28 97.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG09890.1 - 1.5e-18 67.2 0.1 1.4e-17 64.0 0.0 2.3 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Spherulin4 PF12138.8 OAG09891.1 - 6.9e-53 179.8 0.1 8.3e-53 179.5 0.1 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 Amidase02_C PF12123.8 OAG09892.1 - 0.15 11.8 1.4 15 5.4 0.0 2.9 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase Pantoate_ligase PF02569.15 OAG09893.1 - 2.6e-92 308.8 0.0 3.1e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.29 OAG09894.1 - 3.1e-43 147.6 0.1 6e-43 146.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG09894.1 - 5.1e-20 71.9 0.0 1.9e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG09894.1 - 1.3e-16 60.5 0.8 2.8e-16 59.5 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAG09894.1 - 4.6e-07 30.0 0.4 1.2e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG09894.1 - 0.00028 20.2 0.0 0.0009 18.5 0.0 1.7 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DUF2362 PF10154.9 OAG09894.1 - 0.062 12.2 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) SAP PF02037.27 OAG09895.1 - 9.2e-09 34.9 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 OAG09895.1 - 3.7e-08 33.1 11.2 3.7e-08 33.1 11.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG09895.1 - 1.3e-06 28.3 6.3 1.3e-06 28.3 6.3 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG09895.1 - 1.6e-06 28.0 16.2 7.6e-06 25.8 12.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG09895.1 - 4.2e-06 26.5 13.4 4.2e-06 26.5 13.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG09895.1 - 3.6e-05 23.5 18.6 0.00022 21.0 14.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAG09895.1 - 0.00012 21.9 6.5 0.00012 21.9 6.5 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 OAG09895.1 - 0.00098 19.4 12.2 0.00098 19.4 12.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 OAG09895.1 - 0.0025 17.9 8.4 0.0055 16.8 8.4 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OAG09895.1 - 0.0026 17.9 12.7 0.0026 17.9 12.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG09895.1 - 0.0056 16.5 17.7 0.061 13.2 13.7 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 OAG09895.1 - 0.013 15.7 0.0 0.045 13.9 0.0 2.0 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.7 OAG09895.1 - 0.067 13.5 11.5 0.069 13.4 6.6 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain Mob_synth_C PF06463.13 OAG09895.1 - 0.18 11.7 2.9 0.46 10.4 2.9 1.7 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-ribbon_3 PF13248.6 OAG09895.1 - 0.66 9.5 5.2 1.5 8.3 0.1 3.0 2 0 0 2 2 2 0 zinc-ribbon domain Mac PF12464.8 OAG09895.1 - 1.2 9.5 3.5 3.3 8.0 1.0 2.7 2 0 0 2 2 2 0 Maltose acetyltransferase CDC27 PF09507.10 OAG09895.1 - 1.8 7.9 19.0 0.024 14.0 5.3 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF3176 PF11374.8 OAG09899.1 - 0.027 14.7 0.4 0.1 12.8 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3176) F-box PF00646.33 OAG09902.1 - 7.6e-05 22.5 0.1 0.00024 20.9 0.1 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OAG09902.1 - 0.0052 17.2 0.2 0.094 13.2 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAG09902.1 - 0.034 14.0 0.1 0.097 12.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like RNA_pol_Rpb8 PF03870.15 OAG09903.1 - 5.4e-43 146.5 0.0 6e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OAG09903.1 - 0.00043 20.3 0.1 0.4 10.8 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G DUF4743 PF15916.5 OAG09904.1 - 8.2e-14 51.6 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 OAG09904.1 - 7.2e-10 39.0 0.1 1.3e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain PHB_depo_C PF06850.11 OAG09904.1 - 0.04 13.4 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 PHB de-polymerase C-terminus Met_10 PF02475.16 OAG09905.1 - 1.1e-07 31.8 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein EF-hand_6 PF13405.6 OAG09906.1 - 8.5e-07 28.4 0.3 0.0087 15.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OAG09906.1 - 4.6e-06 27.0 0.1 1e-05 25.9 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAG09906.1 - 9e-06 25.0 0.3 2.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 OAG09906.1 - 0.00096 18.5 0.9 0.0018 17.7 0.0 2.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 OAG09906.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair PAXNEB PF05625.11 OAG09907.1 - 3.6e-110 368.6 0.0 4.2e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein MFS_1 PF07690.16 OAG09910.1 - 1.6e-09 37.2 35.8 1.6e-09 37.2 35.8 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 OAG09910.1 - 0.35 10.7 4.1 2.6 7.9 0.2 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain UPF0261 PF06792.11 OAG09911.1 - 3.6e-166 553.1 0.9 4.1e-166 552.9 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) EIF_2_alpha PF07541.12 OAG09911.1 - 0.019 15.0 0.0 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit Dehydratase_MU PF02288.15 OAG09911.1 - 0.12 12.3 2.1 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 Dehydratase medium subunit PEP_hydrolase PF09370.10 OAG09912.1 - 1.6e-136 453.8 0.3 1.8e-136 453.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 OAG09912.1 - 0.00026 20.5 0.1 0.00047 19.6 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Radical_SAM PF04055.21 OAG09912.1 - 0.058 13.8 0.0 0.3 11.5 0.0 2.1 2 1 1 3 3 3 0 Radical SAM superfamily DUF2939 PF11159.8 OAG09913.1 - 0.0059 17.0 0.7 0.0059 17.0 0.7 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2939) DPPIV_N PF00930.21 OAG09916.1 - 1.2e-105 353.2 7.5 1.6e-105 352.8 7.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAG09916.1 - 1.6e-37 129.1 0.6 2.7e-37 128.3 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAG09916.1 - 5.7e-07 29.4 0.1 9.7e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 OAG09916.1 - 0.00022 21.0 0.6 0.11 12.5 0.0 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF2920 PF11144.8 OAG09916.1 - 0.0045 16.2 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) AA_permease_2 PF13520.6 OAG09917.1 - 1.4e-56 192.2 32.7 1.7e-56 191.9 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG09917.1 - 2.1e-25 89.2 31.9 3.6e-25 88.5 20.5 2.3 2 0 0 2 2 2 2 Amino acid permease DUF4533 PF15047.6 OAG09918.1 - 0.00064 19.4 1.4 0.00064 19.4 1.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4533) Apolipoprotein PF01442.18 OAG09918.1 - 0.0025 17.7 11.5 0.08 12.8 0.8 3.1 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain XH PF03469.14 OAG09918.1 - 0.0043 16.9 8.2 0.27 11.1 0.0 3.8 3 1 1 4 4 4 2 XH domain Tam41_Mmp37 PF09139.11 OAG09918.1 - 0.024 14.1 0.4 0.041 13.3 0.4 1.4 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Chloroplast_duf PF14476.6 OAG09918.1 - 0.064 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Petal formation-expressed ApoLp-III PF07464.11 OAG09918.1 - 0.17 11.9 19.8 1.1 9.3 2.2 4.4 4 1 1 5 5 5 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 OAG09918.1 - 0.27 11.8 10.1 8.6 7.0 0.0 4.6 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) Shadoo PF14999.6 OAG09918.1 - 0.4 10.8 3.6 0.74 9.9 3.6 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Peptidase_M41 PF01434.18 OAG09918.1 - 0.72 9.7 7.8 0.55 10.0 0.9 2.7 2 1 1 3 3 3 0 Peptidase family M41 SMBP PF16785.5 OAG09918.1 - 1.4 9.1 8.0 20 5.5 1.4 3.9 3 1 1 4 4 4 0 Small metal-binding protein PhoU PF01895.19 OAG09918.1 - 1.8 9.1 5.2 3.4 8.2 0.1 3.3 3 1 0 3 3 3 0 PhoU domain DnaI_N PF07319.11 OAG09918.1 - 2.2 9.0 5.0 2.2 9.0 0.1 3.1 2 1 0 3 3 3 0 Primosomal protein DnaI N-terminus ATP-synt_B PF00430.18 OAG09918.1 - 3.2 7.8 11.6 11 6.1 6.0 2.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Prefoldin PF02996.17 OAG09918.1 - 3.4 7.6 12.5 6.3 6.7 5.1 3.5 3 1 1 4 4 4 0 Prefoldin subunit REF PF05755.12 OAG09918.1 - 6.1 6.6 7.3 16 5.3 0.6 2.6 2 1 0 2 2 2 0 Rubber elongation factor protein (REF) PhoD PF09423.10 OAG09919.1 - 1.3e-07 31.0 0.1 0.00079 18.5 0.1 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase NYN_YacP PF05991.11 OAG09919.1 - 0.082 12.8 0.1 7.7 6.4 0.1 2.5 2 0 0 2 2 2 0 YacP-like NYN domain Herpes_LMP1 PF05297.11 OAG09919.1 - 6.1 5.9 7.0 9.7 5.3 7.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2293 PF10056.9 OAG09920.1 - 1.7e-30 105.0 0.8 3.5e-30 104.1 0.8 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Glyco_trans_4_2 PF13477.6 OAG09920.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like TatD_DNase PF01026.21 OAG09920.1 - 0.032 13.6 0.1 0.054 12.9 0.1 1.3 1 0 0 1 1 1 0 TatD related DNase Complex1_LYR PF05347.15 OAG09921.1 - 0.0037 17.3 2.5 0.0084 16.1 1.4 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) PI3K_P85_iSH2 PF16454.5 OAG09921.1 - 0.0055 16.3 0.1 0.0094 15.6 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NFACT-R_1 PF05670.13 OAG09922.1 - 3.8e-41 140.1 0.1 6.7e-41 139.3 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain MAJIN PF15077.6 OAG09922.1 - 0.32 10.7 6.5 0.48 10.2 6.5 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein MOZART1 PF12554.8 OAG09923.1 - 1.6e-23 82.2 0.5 1.9e-23 82.0 0.5 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DHHA1 PF02272.19 OAG09923.1 - 0.14 12.6 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 DHHA1 domain Acetyltransf_1 PF00583.25 OAG09924.1 - 1.5e-09 38.1 0.3 2.7e-09 37.3 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG09924.1 - 0.0017 18.7 0.1 0.0093 16.4 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG09924.1 - 0.066 13.2 0.1 0.15 12.0 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG09924.1 - 0.15 12.2 0.2 0.33 11.1 0.2 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 OAG09925.1 - 2.4e-49 168.1 0.0 6.5e-49 166.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG09925.1 - 2.9e-23 82.5 0.0 6.6e-23 81.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG09925.1 - 0.017 14.1 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OAG09925.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG09925.1 - 0.07 12.4 0.0 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Svf1_C PF17187.4 OAG09926.1 - 3.2e-59 199.4 0.0 4.6e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 OAG09926.1 - 8e-51 172.3 0.0 1.2e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain TauD PF02668.16 OAG09928.1 - 5.9e-56 190.2 0.1 8.7e-56 189.7 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OB_NTP_bind PF07717.16 OAG09930.1 - 1.4e-21 76.7 0.0 3e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAG09930.1 - 2.2e-21 76.2 0.0 2.2e-21 76.2 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG09930.1 - 9.8e-14 51.6 0.0 3.2e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 OAG09930.1 - 2.8e-10 40.4 0.5 5.6e-10 39.4 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 OAG09930.1 - 0.0001 22.6 0.2 0.00038 20.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 OAG09930.1 - 0.00011 22.0 0.1 0.00031 20.6 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 OAG09930.1 - 0.00074 18.7 0.1 0.0023 17.0 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 OAG09930.1 - 0.0012 18.6 1.3 0.0022 17.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 OAG09930.1 - 0.016 15.2 0.0 0.15 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG09930.1 - 0.018 14.3 0.0 0.041 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OAG09930.1 - 0.025 14.9 0.1 0.064 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 OAG09930.1 - 0.043 13.8 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding AAA_7 PF12775.7 OAG09930.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 OAG09930.1 - 0.048 13.3 0.1 0.094 12.3 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OAG09930.1 - 0.052 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Rhodanese PF00581.20 OAG09930.1 - 0.15 12.6 0.0 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 Rhodanese-like domain AA_permease_2 PF13520.6 OAG09931.1 - 3.1e-55 187.7 45.9 3.9e-55 187.4 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG09931.1 - 5.8e-20 71.3 39.5 8.9e-20 70.7 39.5 1.2 1 0 0 1 1 1 1 Amino acid permease DUF423 PF04241.15 OAG09931.1 - 3.9 7.7 10.8 0.63 10.3 0.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF423) MFS_1 PF07690.16 OAG09932.1 - 1.1e-15 57.5 21.1 1.1e-15 57.5 21.1 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG09932.1 - 1.4e-09 37.9 4.6 3.7e-09 36.5 4.6 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 OAG09932.1 - 0.00035 19.5 5.2 0.00035 19.5 5.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Peptidase_M48_N PF16491.5 OAG09932.1 - 0.74 9.7 12.3 0.16 11.8 0.4 3.9 3 2 1 4 4 4 0 CAAX prenyl protease N-terminal, five membrane helices DUF4131 PF13567.6 OAG09932.1 - 3 7.5 7.7 5.3 6.7 0.1 3.7 2 1 1 4 4 4 0 Domain of unknown function (DUF4131) TauD PF02668.16 OAG09933.1 - 5.4e-38 131.3 0.1 8.3e-38 130.7 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_28 PF00295.17 OAG09934.1 - 8.7e-60 202.5 7.9 1.2e-59 202.0 7.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_6 PF01341.17 OAG09935.1 - 6.6e-108 361.0 2.4 9e-108 360.6 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 OAG09935.1 - 3.7e-13 49.2 6.9 3.7e-13 49.2 6.9 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Alpha-amylase PF00128.24 OAG09936.1 - 3.1e-114 382.0 0.1 5.2e-114 381.3 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OAG09936.1 - 1.4e-05 25.1 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OAG09936.1 - 8.8e-05 21.8 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Phosphoprotein PF00922.17 OAG09937.1 - 0.073 12.7 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Ctr PF04145.15 OAG09938.1 - 6.3e-23 82.0 0.0 7.3e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Spherulin4 PF12138.8 OAG09939.1 - 5.6e-66 222.6 0.1 6.3e-66 222.4 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF2106 PF09879.9 OAG09939.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Asp PF00026.23 OAG09940.1 - 0.00049 19.6 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease CarboxypepD_reg PF13620.6 OAG09941.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain peroxidase PF00141.23 OAG09942.1 - 8.8e-26 91.0 0.1 2.6e-25 89.5 0.1 1.7 1 1 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 OAG09942.1 - 2.6e-06 27.2 0.0 6.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region HA2 PF04408.23 OAG09943.1 - 2.6e-17 63.1 0.1 5.5e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG09943.1 - 2.9e-14 53.2 0.0 5.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG09943.1 - 6.1e-11 42.6 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG09943.1 - 1.3e-06 28.4 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAG09943.1 - 6.8e-05 22.7 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG09943.1 - 0.00024 21.4 0.0 0.00058 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG09943.1 - 0.0069 16.7 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 OAG09943.1 - 0.01 15.4 0.2 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OAG09943.1 - 0.019 15.5 0.2 0.046 14.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAG09943.1 - 0.099 11.7 0.4 0.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 OAG09943.1 - 0.26 11.8 1.2 1.6 9.3 0.1 2.7 3 1 1 4 4 4 0 ABC transporter Spindle_Spc25 PF08234.12 OAG09944.1 - 2.3e-26 91.8 0.1 5.6e-26 90.5 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Atg14 PF10186.9 OAG09944.1 - 0.25 10.4 4.7 0.42 9.6 4.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 OAG09944.1 - 2.1 7.5 6.2 2.9 7.0 6.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Rrn6 PF10214.9 OAG09945.1 - 1.1e-170 570.0 4.6 1.3e-170 569.8 4.6 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor tRNA_bind_2 PF13725.6 OAG09945.1 - 0.15 11.7 1.4 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Possible tRNA binding domain adh_short_C2 PF13561.6 OAG09947.1 - 1.7e-60 204.5 0.0 2.1e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG09947.1 - 6.2e-51 172.6 0.0 7.3e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG09947.1 - 1.9e-15 57.3 0.0 3.4e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG09947.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TRI12 PF06609.13 OAG09948.1 - 2.9e-44 151.5 28.8 3.9e-44 151.1 28.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG09948.1 - 8.2e-12 44.7 58.4 9.8e-12 44.4 55.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3087 PF11286.8 OAG09948.1 - 0.064 12.7 3.9 1.5 8.3 1.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3087) FMO-like PF00743.19 OAG09949.1 - 7.1e-16 57.7 0.3 1.4e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG09949.1 - 3.1e-15 56.2 0.0 1.9e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG09949.1 - 8e-10 38.4 0.0 2.5e-08 33.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG09949.1 - 2.3e-07 30.4 0.0 6.5e-06 25.6 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG09949.1 - 4e-05 23.8 0.1 0.00082 19.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG09949.1 - 0.00016 22.2 0.9 0.024 15.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG09949.1 - 0.013 15.1 0.1 13 5.2 0.0 3.4 2 1 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG09949.1 - 0.19 11.0 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG09949.1 - 0.23 10.1 1.1 6.8 5.3 0.0 2.6 3 1 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 OAG09949.1 - 4.5 6.2 5.0 7.1 5.6 0.1 3.1 3 1 0 4 4 4 0 Glucose inhibited division protein A Arginase PF00491.21 OAG09950.1 - 1.6e-80 270.6 0.2 2.1e-80 270.2 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAG09950.1 - 0.23 11.7 0.1 0.35 11.1 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain Cyt-b5 PF00173.28 OAG09951.1 - 0.0083 16.3 0.0 0.0093 16.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 OAG09952.1 - 2.1e-60 200.5 0.3 4.9e-18 64.7 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG09952.1 - 2.1e-07 30.6 0.0 0.0037 16.9 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAG09952.1 - 0.00048 20.4 10.1 5.9 7.1 0.0 6.2 5 3 1 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter TFIIA PF03153.13 OAG09952.1 - 0.00059 19.9 13.9 0.00059 19.9 13.9 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RRM_occluded PF16842.5 OAG09952.1 - 0.01 15.7 0.0 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OAG09952.1 - 0.011 15.8 2.3 0.97 9.5 0.1 4.1 5 0 0 5 5 5 0 Limkain b1 RRM_7 PF16367.5 OAG09952.1 - 0.02 15.0 0.2 9.1 6.5 0.0 3.8 4 0 0 4 4 4 0 RNA recognition motif DbpA PF03880.15 OAG09952.1 - 0.069 13.1 0.2 11 6.1 0.0 2.8 2 0 0 2 2 2 0 DbpA RNA binding domain Aldo_ket_red PF00248.21 OAG09954.1 - 9.3e-73 245.0 0.0 1.1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 OAG09954.1 - 0.12 12.4 0.7 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Ribosomal_L6 PF00347.23 OAG09955.1 - 7.5e-27 93.8 7.2 3e-13 50.2 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Zn_clus PF00172.18 OAG09956.1 - 1.7e-07 31.3 14.2 1.7e-07 31.3 14.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhabdo_NV PF02484.15 OAG09957.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein Aminotran_3 PF00202.21 OAG09958.1 - 5.6e-39 133.9 0.0 6.7e-18 64.5 0.0 3.2 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 OAG09958.1 - 9.9e-15 54.9 0.0 1.6e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain LAL_C2 PF18603.1 OAG09958.1 - 0.17 12.0 0.1 0.4 10.9 0.1 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Aminotran_1_2 PF00155.21 OAG09959.1 - 8.3e-41 140.4 0.0 9.6e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG09959.1 - 0.011 14.3 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme E3_UbLigase_EDD PF11547.8 OAG09959.1 - 0.11 12.2 0.0 7.8 6.3 0.0 2.6 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD BATS PF06968.13 OAG09960.1 - 5.2e-23 81.0 0.4 1.7e-22 79.3 0.1 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OAG09960.1 - 1.7e-13 51.3 0.4 1.7e-12 48.0 0.0 2.3 3 0 0 3 3 3 1 Radical SAM superfamily GCP_N_terminal PF17681.1 OAG09961.1 - 8.3e-33 114.3 0.4 1.5e-32 113.4 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAG09961.1 - 3.1e-24 86.0 0.0 7.1e-24 84.8 0.0 1.5 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Alpha_GJ PF03229.13 OAG09962.1 - 0.006 17.1 7.3 0.014 15.9 7.3 1.6 1 0 0 1 1 1 1 Alphavirus glycoprotein J DUF3123 PF11321.8 OAG09962.1 - 0.36 11.5 6.0 1.5 9.5 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DUF908 PF06012.12 OAG09962.1 - 1.5 8.2 5.6 2 7.7 5.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MSA-2c PF12238.8 OAG09962.1 - 5.9 6.8 8.7 12 5.8 8.7 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c GDA1_CD39 PF01150.17 OAG09963.1 - 1.1e-104 350.5 0.0 1.5e-104 350.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GATase PF00117.28 OAG09964.1 - 1.1e-13 51.4 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OAG09964.1 - 0.0043 16.7 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 OAG09965.1 - 1.8e-35 122.6 44.5 1.8e-35 122.6 44.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAG09965.1 - 0.39 8.9 8.3 0.074 11.3 2.4 2.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Cation_ATPase_C PF00689.21 OAG09967.1 - 3.5e-47 160.5 8.6 3.5e-47 160.5 8.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAG09967.1 - 5.7e-38 130.2 0.4 5.7e-38 130.2 0.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OAG09967.1 - 5.7e-20 72.5 1.1 1.4e-18 68.0 1.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG09967.1 - 7.9e-19 67.5 0.0 1.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG09967.1 - 2.5e-09 36.7 0.1 2.7e-07 30.2 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG09967.1 - 2.5e-06 27.4 0.1 4.1e-05 23.4 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 OAG09967.1 - 0.0043 15.9 2.0 0.011 14.7 2.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Phage_holin_3_6 PF07332.11 OAG09967.1 - 5.5 7.1 17.6 1.4 9.0 1.8 3.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Pmp3 PF01679.17 OAG09968.1 - 6.6e-12 45.4 11.2 1.3e-11 44.5 3.1 2.2 1 1 1 2 2 2 2 Proteolipid membrane potential modulator MAPEG PF01124.18 OAG09969.1 - 2.9e-20 72.5 1.0 3.6e-20 72.2 1.0 1.1 1 0 0 1 1 1 1 MAPEG family CAP PF00188.26 OAG09970.1 - 1.7e-17 64.5 2.1 2.1e-17 64.1 2.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MMS1_N PF10433.9 OAG09971.1 - 3.1e-134 448.3 0.0 4.5e-134 447.7 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAG09971.1 - 9.3e-74 248.6 0.0 3.4e-73 246.8 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region HPS3_N PF14761.6 OAG09971.1 - 0.011 15.3 0.3 0.36 10.3 0.1 2.9 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Ntox30 PF15532.6 OAG09971.1 - 0.056 13.8 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial toxin 30 Sin_N PF04801.13 OAG09972.1 - 5.2e-28 98.4 2.5 3.7e-27 95.6 2.5 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region NAD_binding_2 PF03446.15 OAG09973.1 - 5.7e-37 127.3 0.1 9.6e-37 126.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG09973.1 - 2.1e-24 86.1 0.0 3.4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG09973.1 - 1.9e-06 28.3 0.0 6.2e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 OAG09973.1 - 0.00045 21.0 0.0 0.0048 17.7 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.15 OAG09973.1 - 0.00088 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family IlvN PF07991.12 OAG09973.1 - 0.02 14.5 0.0 0.094 12.3 0.0 2.1 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 OAG09973.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_6 PF13516.6 OAG09974.1 - 2.1e-10 39.8 8.0 0.32 11.2 0.0 8.5 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 OAG09974.1 - 0.97 10.2 5.3 2.9e+02 2.7 0.1 5.5 4 1 0 4 4 4 0 Leucine Rich Repeat TRI12 PF06609.13 OAG09976.1 - 1.4e-34 119.5 30.2 1.7e-34 119.2 30.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG09976.1 - 8e-20 71.1 48.3 8e-20 71.1 48.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG09976.1 - 1.1e-07 31.1 14.2 1.1e-07 31.1 14.2 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 OAG09976.1 - 0.033 14.5 0.3 0.033 14.5 0.3 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3522) GATA PF00320.27 OAG09977.1 - 6e-30 102.6 17.0 5.3e-15 54.7 3.5 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAG09977.1 - 3.4e-06 26.5 6.7 0.0026 17.2 0.7 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zf-RRN7 PF11781.8 OAG09977.1 - 1.9e-05 24.2 4.7 0.013 15.2 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 OAG09977.1 - 0.00031 20.8 8.4 0.04 14.0 0.1 2.8 3 0 0 3 3 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 OAG09977.1 - 0.001 19.0 5.3 0.039 13.9 0.5 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF2387 PF09526.10 OAG09977.1 - 0.0011 19.1 0.6 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 Probable metal-binding protein (DUF2387) ArfGap PF01412.18 OAG09977.1 - 0.0028 17.7 2.5 1.2 9.2 0.2 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 OAG09977.1 - 0.0095 16.1 7.9 0.12 12.6 0.3 2.7 3 0 0 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TDP43_N PF18694.1 OAG09977.1 - 0.016 15.0 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DZR PF12773.7 OAG09977.1 - 0.15 12.1 11.6 0.61 10.2 0.3 3.0 3 1 1 4 4 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 OAG09977.1 - 0.16 11.9 5.1 4.8 7.1 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-Sec23_Sec24 PF04810.15 OAG09977.1 - 0.52 10.4 7.7 0.22 11.6 0.6 2.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger A2L_zn_ribbon PF08792.10 OAG09977.1 - 0.64 9.8 6.9 59 3.5 2.4 3.8 3 1 0 3 3 3 0 A2L zinc ribbon domain Nudix_N_2 PF14803.6 OAG09977.1 - 2.3 8.2 11.9 7 6.7 2.4 3.1 2 1 0 2 2 2 0 Nudix N-terminal Ribosomal_L32p PF01783.23 OAG09977.1 - 3.6 7.9 11.7 17 5.8 2.6 4.6 3 2 0 3 3 3 0 Ribosomal L32p protein family COPI_assoc PF08507.10 OAG09978.1 - 4.2e-33 114.2 1.9 4.5e-33 114.1 1.9 1.0 1 0 0 1 1 1 1 COPI associated protein TMEM72 PF16054.5 OAG09978.1 - 0.0079 15.9 2.0 2 8.1 0.5 2.1 2 0 0 2 2 2 2 Transmembrane protein family 72 DUF2964 PF11177.8 OAG09978.1 - 0.041 14.1 1.1 0.041 14.1 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) Tmemb_14 PF03647.13 OAG09978.1 - 0.72 10.6 7.7 1.2 10.0 7.7 1.4 1 1 0 1 1 1 0 Transmembrane proteins 14C Ring_hydroxyl_A PF00848.19 OAG09981.1 - 5.8e-23 82.0 2.3 1e-12 48.5 0.6 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Methyltransf_FA PF12248.8 OAG09981.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase DIM1 PF02966.16 OAG09982.1 - 9.9e-58 193.6 0.1 1.1e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OAG09982.1 - 0.009 16.0 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Sec1 PF00995.23 OAG09983.1 - 3.4e-118 396.4 0.0 3.9e-118 396.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF218 PF02698.17 OAG09983.1 - 0.18 11.9 0.0 0.63 10.1 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain SUV3_C PF12513.8 OAG09984.1 - 4.4e-18 64.9 0.8 1.1e-17 63.7 0.8 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 OAG09984.1 - 2.6e-12 46.4 0.1 6.2e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 OAG09984.1 - 3.4e-10 40.3 0.0 9.3e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Band_7 PF01145.25 OAG09984.1 - 0.049 13.6 0.4 0.092 12.7 0.4 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family Kei1 PF08552.11 OAG09985.1 - 1.5e-56 191.3 2.8 1.5e-56 191.3 2.8 1.3 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 Glyco_hydro_2_N PF02837.18 OAG09986.1 - 1.6e-12 47.7 0.3 3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 OAG09986.1 - 1e-11 44.5 0.1 3.4e-10 39.5 0.1 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 OAG09986.1 - 1.3e-10 41.9 0.0 3.1e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MPS2 PF17060.5 OAG09990.1 - 0.15 11.3 4.9 0.11 11.8 0.7 2.5 3 0 0 3 3 3 0 Monopolar spindle protein 2 DUF2951 PF11166.8 OAG09990.1 - 8 6.8 6.3 13 6.1 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) K_trans PF02705.16 OAG09991.1 - 8.1e-187 622.0 16.4 8.1e-187 622.0 16.4 1.8 2 0 0 2 2 2 1 K+ potassium transporter SET PF00856.28 OAG09993.1 - 3.7e-14 53.5 0.0 4.7e-13 49.9 0.0 2.3 1 1 0 1 1 1 1 SET domain DUF1664 PF07889.12 OAG09995.1 - 2.8e-05 24.1 10.2 0.45 10.6 2.8 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF1664) COG2 PF06148.11 OAG09995.1 - 0.00082 19.5 4.5 0.069 13.2 1.5 3.0 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 MtrG PF04210.13 OAG09995.1 - 0.0055 16.5 0.6 0.17 11.8 0.2 2.7 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, subunit G Baculo_PEP_C PF04513.12 OAG09995.1 - 0.056 13.5 10.7 0.16 12.0 4.4 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.9 OAG09995.1 - 0.098 12.8 4.5 0.36 11.0 2.2 2.5 2 2 0 2 2 2 0 Golgi transport complex subunit 5 Fib_alpha PF08702.10 OAG09995.1 - 0.14 12.4 6.1 13 5.9 5.6 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 OAG09995.1 - 0.17 12.3 11.8 11 6.6 2.5 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein CENP-K PF11802.8 OAG09995.1 - 0.18 11.3 2.2 0.31 10.6 2.2 1.5 1 1 0 1 1 1 0 Centromere-associated protein K DASH_Dad2 PF08654.10 OAG09995.1 - 0.33 11.4 4.2 6.2 7.3 1.3 3.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 Syntaxin_2 PF14523.6 OAG09995.1 - 0.34 11.3 8.5 5.6 7.4 2.0 3.6 1 1 2 3 3 3 0 Syntaxin-like protein DUF713 PF05218.14 OAG09995.1 - 1.1 8.9 4.1 2 8.1 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF713) DUF5638 PF18688.1 OAG09995.1 - 2.2 8.6 5.5 1.8 8.9 0.7 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5638) FlaC_arch PF05377.11 OAG09995.1 - 2.7 8.4 7.0 21 5.6 0.3 3.8 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 OAG09995.1 - 2.9 8.6 4.8 7 7.4 0.1 2.8 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) TPR_10 PF13374.6 OAG09996.1 - 4e-28 96.5 0.0 5.1e-11 42.1 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG09996.1 - 1.5e-27 95.7 0.0 1.1e-12 48.1 0.0 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 OAG09996.1 - 2.3e-06 27.0 0.0 6.8e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 OAG09996.1 - 2.1e-05 24.2 0.5 0.022 14.7 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 OAG09996.1 - 2.3e-05 24.4 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.17 OAG09996.1 - 0.002 18.1 0.1 12 6.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG09996.1 - 0.014 16.0 2.0 1.3 9.7 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG09996.1 - 0.025 15.2 0.1 12 6.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_25 PF13481.6 OAG09996.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.6 OAG09996.1 - 0.11 13.3 3.5 28 5.9 0.0 5.4 6 1 1 7 7 7 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 OAG09997.1 - 3.2e-07 31.2 0.0 3.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG09997.1 - 1.8e-06 27.8 0.0 8.4e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 OAG09997.1 - 1.2e-05 25.1 0.1 1.8e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.18 OAG09997.1 - 3.9e-05 23.3 0.0 6.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.14 OAG09997.1 - 4.4e-05 23.1 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAG09997.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 OAG09997.1 - 0.00091 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase LCAT PF02450.15 OAG09997.1 - 0.001 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase UPF0565 PF10561.9 OAG09997.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 Palm_thioest PF02089.15 OAG09997.1 - 0.0046 16.8 0.3 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Cutinase PF01083.22 OAG09997.1 - 0.0059 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG09997.1 - 0.0072 15.9 0.1 2 7.9 0.0 2.2 2 0 0 2 2 2 2 PE-PPE domain Thioesterase PF00975.20 OAG09997.1 - 0.012 15.8 0.0 0.03 14.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain LIDHydrolase PF10230.9 OAG09997.1 - 0.054 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 OAG09997.1 - 0.058 13.3 0.1 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase DUF3089 PF11288.8 OAG09997.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) adh_short PF00106.25 OAG09998.1 - 6.7e-22 77.9 0.0 6.6e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG09998.1 - 2e-12 47.2 0.0 6.1e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG09998.1 - 9.3e-06 25.7 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG09998.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG09998.1 - 0.04 14.0 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG09998.1 - 0.13 12.5 0.0 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GDH_N PF12466.8 OAG09999.1 - 0.096 12.9 0.2 0.31 11.3 0.2 1.9 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Fungal_trans PF04082.18 OAG10000.1 - 2.2e-22 79.4 0.0 3.5e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10000.1 - 3.9e-07 30.1 13.4 6.2e-07 29.4 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.9 OAG10000.1 - 0.37 9.9 6.0 0.65 9.1 6.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.18 OAG10001.1 - 2.8e-13 49.5 0.7 4.5e-13 48.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10001.1 - 2.7e-08 33.8 10.0 4.4e-08 33.1 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 OAG10002.1 - 1.5e-07 31.4 8.8 3.3e-07 30.3 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG10003.1 - 1.1e-06 27.7 4.1 7.2e-06 25.1 4.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sulfate_transp PF00916.20 OAG10004.1 - 3.3e-101 338.8 17.9 4.3e-101 338.4 17.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG10004.1 - 9.2e-08 31.7 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OAG10004.1 - 0.05 13.9 0.8 0.23 11.8 0.0 2.4 2 0 0 2 2 2 0 STAS domain MFS_MOT1 PF16983.5 OAG10004.1 - 0.34 11.3 19.3 0.39 11.1 6.1 2.7 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily VPS9 PF02204.18 OAG10005.1 - 5.6e-27 94.0 0.0 9.2e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAG10005.1 - 4.3e-15 55.8 0.2 9.4e-15 54.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 OAG10005.1 - 2e-08 33.7 0.0 3.1e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.21 OAG10006.1 - 4e-14 53.0 0.1 5.9e-08 32.7 0.5 3.1 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OAG10006.1 - 3.2e-06 27.1 0.0 0.00011 22.1 0.0 3.1 3 1 0 3 3 3 1 Glutamine amidotransferase domain DUF4202 PF13875.6 OAG10008.1 - 5.7e-70 235.0 0.0 6.6e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) zf-C2H2 PF00096.26 OAG10010.1 - 6.1e-07 29.5 7.3 0.01 16.3 0.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG10010.1 - 0.0001 22.9 5.7 0.0043 17.8 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAG10010.1 - 0.0018 18.6 0.7 0.0073 16.7 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OAG10010.1 - 0.0031 17.4 2.0 0.037 13.9 0.0 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-MYST PF17772.1 OAG10010.1 - 0.091 12.4 1.0 3.3 7.4 0.0 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 OAG10010.1 - 0.28 11.3 6.6 0.37 10.8 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HET PF06985.11 OAG10012.1 - 4.7e-23 82.2 0.1 8.6e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Thioredoxin PF00085.20 OAG10013.1 - 2.3e-27 95.0 0.5 2.9e-27 94.7 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAG10013.1 - 0.00032 21.1 0.5 0.0011 19.4 0.5 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OAG10013.1 - 0.00054 19.7 0.1 0.00079 19.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAG10013.1 - 0.00072 19.8 0.1 0.01 16.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 OAG10013.1 - 0.002 17.5 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 OAG10013.1 - 0.031 14.4 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 OAG10013.1 - 0.13 12.0 0.2 0.37 10.5 0.2 1.6 1 1 1 2 2 2 0 Redoxin COX15-CtaA PF02628.15 OAG10015.1 - 0.035 13.2 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein Nuf2 PF03800.14 OAG10016.1 - 3.9e-40 137.2 0.1 9.6e-40 135.9 0.1 1.7 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 OAG10016.1 - 2.3e-31 108.3 17.8 2.3e-31 108.3 17.8 4.1 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain DASH_Dam1 PF08653.10 OAG10016.1 - 1.8 8.4 9.2 1.2 9.0 0.3 4.0 4 1 0 4 4 4 0 DASH complex subunit Dam1 ApoO PF09769.9 OAG10016.1 - 1.8 8.5 6.2 24 4.9 0.1 3.6 3 1 0 3 3 3 0 Apolipoprotein O Atg14 PF10186.9 OAG10016.1 - 2.4 7.2 38.8 0.22 10.6 18.2 2.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosom_S12_S23 PF00164.25 OAG10018.1 - 7.7e-32 109.3 0.9 1.1e-31 108.8 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF4648 PF15505.6 OAG10018.1 - 0.025 15.4 0.4 0.057 14.3 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) Ribosomal_S12 PF17487.2 OAG10018.1 - 0.16 12.7 0.0 0.38 11.5 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S12 WD40 PF00400.32 OAG10020.1 - 8.3e-92 298.6 34.4 1.6e-12 47.7 0.3 8.2 8 0 0 8 8 7 7 WD domain, G-beta repeat NACHT PF05729.12 OAG10020.1 - 1e-23 84.1 0.1 2.2e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 OAG10020.1 - 4.1e-22 78.3 2.4 0.059 13.7 0.1 7.4 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG10020.1 - 8.8e-12 44.6 9.7 0.0037 16.3 0.3 5.7 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG10020.1 - 2.3e-10 39.8 12.9 0.75 8.4 0.1 7.1 2 1 4 7 7 7 6 Nucleoporin Nup120/160 HET PF06985.11 OAG10020.1 - 5.6e-09 36.5 5.3 1.8e-06 28.3 0.4 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Nucleoporin_N PF08801.11 OAG10020.1 - 3.2e-07 29.5 8.9 0.094 11.4 0.2 6.6 2 1 6 8 8 8 3 Nup133 N terminal like WD40_like PF17005.5 OAG10020.1 - 8.2e-05 22.1 0.0 0.16 11.3 0.0 3.7 3 1 1 5 5 5 1 WD40-like domain AAA_16 PF13191.6 OAG10020.1 - 0.0016 18.8 0.4 0.012 16.0 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain Cytochrom_D1 PF02239.16 OAG10020.1 - 0.0022 16.6 2.4 1.4 7.4 0.1 3.3 2 1 3 5 5 5 3 Cytochrome D1 heme domain DUF3748 PF12566.8 OAG10020.1 - 0.013 15.5 0.3 1.8 8.6 0.0 4.1 3 2 3 6 6 6 0 Protein of unknown function (DUF3748) Methyltransf_10 PF05971.12 OAG10020.1 - 0.024 14.0 0.1 2.2 7.5 0.0 2.6 2 1 0 2 2 2 0 RNA methyltransferase GidB PF02527.15 OAG10020.1 - 0.04 13.2 0.6 2.7e+02 0.8 0.0 5.5 7 0 0 7 7 7 0 rRNA small subunit methyltransferase G CDtoxinA PF03498.14 OAG10020.1 - 0.055 13.0 0.0 7.5 6.1 0.0 3.2 2 1 2 4 4 4 0 Cytolethal distending toxin A/C domain AAA_19 PF13245.6 OAG10020.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PD40 PF07676.12 OAG10020.1 - 0.099 12.6 18.5 18 5.4 0.2 6.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat RicinB_lectin_2 PF14200.6 OAG10020.1 - 0.37 11.6 9.2 16 6.3 0.4 4.0 1 1 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like NAD_binding_10 PF13460.6 OAG10021.1 - 8.4e-22 77.9 2.1 3.5e-21 75.9 2.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG10021.1 - 0.023 14.2 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG10021.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MOR2-PAG1_N PF14222.6 OAG10023.1 - 1.6e-196 654.6 0.0 2.5e-196 653.9 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 OAG10023.1 - 4.4e-88 295.4 0.7 1.2e-87 294.0 0.1 2.2 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 OAG10023.1 - 3.4e-34 117.8 11.6 1.2e-14 53.1 0.2 4.5 3 1 1 4 4 4 3 Cell morphogenesis central region HEAT_EZ PF13513.6 OAG10023.1 - 0.011 16.3 0.9 10 6.8 0.0 5.5 5 0 0 5 5 5 0 HEAT-like repeat Peptidase_M13_N PF05649.13 OAG10023.1 - 0.062 13.0 1.0 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Peptidase family M13 FAD_binding_1 PF00667.20 OAG10024.1 - 7.2e-63 212.1 0.0 1e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG10024.1 - 1.3e-35 122.7 1.1 1.3e-35 122.7 1.1 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 OAG10024.1 - 8.3e-21 74.7 0.1 1.3e-19 70.9 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Beta-Casp PF10996.8 OAG10024.1 - 0.047 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Beta-Casp domain RRM_1 PF00076.22 OAG10025.1 - 4.7e-23 80.8 0.0 3.4e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OAG10025.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 RIO1 PF01163.22 OAG10027.1 - 1.2e-42 145.7 0.0 2.2e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 OAG10027.1 - 4.4e-30 103.7 0.0 1.4e-29 102.2 0.0 1.9 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 OAG10027.1 - 8.1e-08 31.9 0.0 8.4e-06 25.3 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG10027.1 - 5.3e-07 29.8 0.0 0.006 16.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RPN1_RPN2_N PF17781.1 OAG10028.1 - 3.5e-121 404.4 1.6 5.8e-121 403.6 1.6 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OAG10028.1 - 1.6e-29 101.7 0.0 3e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OAG10028.1 - 2e-21 75.2 21.0 1.3e-06 28.6 0.2 9.0 9 0 0 9 9 9 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAG10028.1 - 7.7e-07 29.4 3.6 0.0015 18.8 0.0 4.3 5 1 1 6 6 6 2 HEAT repeats IFRD PF05004.13 OAG10028.1 - 0.0043 16.2 0.3 0.063 12.4 0.2 2.7 1 1 1 2 2 2 1 Interferon-related developmental regulator (IFRD) TPR_15 PF13429.6 OAG10028.1 - 0.086 12.0 1.7 0.11 11.7 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 OAG10030.1 - 4.2e-88 292.5 0.0 6.4e-45 152.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG10030.1 - 1.4e-20 72.8 1.6 3.1e-10 39.7 0.2 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OAG10030.1 - 3.1e-13 50.5 2.0 0.00086 19.7 0.0 4.7 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 OAG10030.1 - 5.5e-11 42.6 0.2 0.00036 20.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG10030.1 - 7.1e-11 42.1 0.0 0.00021 21.0 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG10030.1 - 8.7e-10 39.0 2.7 0.025 14.9 0.1 5.2 2 2 3 5 5 5 2 AAA domain AAA_2 PF07724.14 OAG10030.1 - 1.7e-09 38.0 0.0 0.0017 18.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAG10030.1 - 1.6e-08 34.8 0.0 0.0051 17.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 OAG10030.1 - 2e-07 30.6 0.2 0.0075 15.5 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_3 PF07726.11 OAG10030.1 - 2.5e-07 30.6 0.0 0.005 16.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAG10030.1 - 8.8e-07 29.0 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAG10030.1 - 9.3e-07 29.2 0.0 0.037 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OAG10030.1 - 1.1e-06 29.2 0.0 0.19 12.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 OAG10030.1 - 1.4e-06 27.9 0.1 0.023 14.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG10030.1 - 2.7e-06 27.7 0.0 0.1 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 OAG10030.1 - 4e-06 26.9 0.0 0.073 13.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 OAG10030.1 - 8.7e-06 25.8 0.0 0.05 13.5 0.0 2.8 2 0 0 2 2 2 2 Rad17 P-loop domain IstB_IS21 PF01695.17 OAG10030.1 - 2.7e-05 24.0 0.0 0.062 13.0 0.1 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 OAG10030.1 - 2.8e-05 23.5 0.0 0.059 12.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 OAG10030.1 - 6.2e-05 22.3 0.0 0.017 14.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase PF06745.13 OAG10030.1 - 0.00011 21.6 0.1 0.31 10.3 0.0 2.8 2 1 1 3 3 3 2 KaiC AAA_17 PF13207.6 OAG10030.1 - 0.00029 21.3 0.0 1.2 9.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OAG10030.1 - 0.00035 20.1 0.1 1.5 8.3 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 OAG10030.1 - 0.00035 20.2 0.5 1.2 8.6 0.1 3.0 2 1 1 3 3 3 2 AAA domain NACHT PF05729.12 OAG10030.1 - 0.00035 20.5 1.1 1.1 9.2 0.0 3.5 4 0 0 4 4 3 2 NACHT domain SKI PF01202.22 OAG10030.1 - 0.00095 19.3 0.0 0.36 10.9 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase ABC_tran PF00005.27 OAG10030.1 - 0.00098 19.7 0.0 0.36 11.3 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 OAG10030.1 - 0.0012 18.6 0.0 0.27 10.9 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 OAG10030.1 - 0.0013 18.5 2.1 1.7 8.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 OAG10030.1 - 0.0017 17.8 0.1 0.21 11.0 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.22 OAG10030.1 - 0.0029 16.9 0.0 2.9 7.0 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.18 OAG10030.1 - 0.0033 17.2 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 OAG10030.1 - 0.0034 17.1 0.0 0.97 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 OAG10030.1 - 0.0059 16.8 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family CPT PF07931.12 OAG10030.1 - 0.0063 16.4 0.1 0.39 10.5 0.0 2.9 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.6 OAG10030.1 - 0.0075 16.4 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 OAG10030.1 - 0.0083 15.6 0.0 2.3 7.6 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein ATPase_2 PF01637.18 OAG10030.1 - 0.013 15.4 0.0 4.8 7.0 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 OAG10030.1 - 0.015 15.7 1.2 6.4 7.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 OAG10030.1 - 0.035 13.8 0.2 4.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase ResIII PF04851.15 OAG10030.1 - 0.066 13.2 0.1 16 5.5 0.0 2.9 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 OAG10030.1 - 0.12 12.1 0.0 9.1 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 OAG10030.1 - 0.13 11.3 0.1 2.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 OAG10030.1 - 0.15 12.0 0.3 7.1 6.5 0.0 2.8 2 1 0 2 2 2 0 NTPase Snf7 PF03357.21 OAG10031.1 - 1.4e-32 112.7 14.2 1.4e-32 112.7 14.2 1.3 1 1 0 1 1 1 1 Snf7 Nop53 PF07767.11 OAG10031.1 - 0.0037 16.7 11.4 0.0037 16.7 11.4 2.1 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) IL22 PF14565.6 OAG10031.1 - 0.01 16.1 0.1 0.019 15.3 0.1 1.4 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL34 PF15036.6 OAG10031.1 - 0.063 13.3 0.3 0.17 11.9 0.1 1.8 1 1 1 2 2 2 0 Interleukin 34 Silic_transp PF03842.13 OAG10031.1 - 0.95 7.7 1.9 0.85 7.8 0.8 1.3 1 1 0 1 1 1 0 Silicon transporter PITH PF06201.13 OAG10032.1 - 3.4e-43 147.5 0.1 4.2e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 PITH domain LSM PF01423.22 OAG10033.1 - 8.1e-18 63.9 0.0 1.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain Herpes_UL6 PF01763.16 OAG10035.1 - 0.0017 17.0 0.0 0.0019 16.8 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like Urocanase PF01175.18 OAG10036.1 - 0.0074 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Urocanase Rossmann-like domain DUF3824 PF12868.7 OAG10036.1 - 0.18 12.4 3.6 0.16 12.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) ADH_zinc_N_2 PF13602.6 OAG10037.1 - 1.2e-12 49.0 0.0 2.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG10037.1 - 7.8e-10 38.8 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG10037.1 - 1.1e-08 34.9 0.0 2.4e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 OAG10038.1 - 2.3e-39 135.3 23.9 2.3e-39 135.3 23.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 OAG10039.1 - 1.1e-12 47.8 0.0 1.4e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10039.1 - 2.9e-12 46.7 0.0 3.2e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase BAT PF15915.5 OAG10039.1 - 0.0026 17.7 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 GAF and HTH_10 associated domain Peptidase_M19 PF01244.21 OAG10039.1 - 0.2 10.8 0.0 0.27 10.4 0.0 1.3 1 1 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Pyr_redox_3 PF13738.6 OAG10040.1 - 1.3e-15 57.5 0.0 3.3e-13 49.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG10040.1 - 1.8e-15 57.0 0.0 5.7e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG10040.1 - 5e-14 51.6 0.1 9.6e-12 44.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG10040.1 - 2.5e-07 30.2 0.0 2.3e-05 23.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG10040.1 - 0.0016 19.0 0.0 0.75 10.4 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG10040.1 - 0.0041 17.3 0.0 0.029 14.6 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain IlvN PF07991.12 OAG10040.1 - 0.011 15.3 0.0 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 OAG10040.1 - 0.039 14.0 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG10040.1 - 0.055 12.7 0.0 0.53 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 OAG10040.1 - 0.096 12.0 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAG10040.1 - 0.18 11.7 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_deac_1 PF01522.21 OAG10041.1 - 5.3e-17 61.9 0.0 9.3e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG10041.1 - 1.2e-07 31.6 0.1 2.1e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) adh_short PF00106.25 OAG10042.1 - 7.1e-28 97.4 0.0 8.9e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10042.1 - 1.1e-19 71.0 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10042.1 - 4.2e-06 26.8 0.0 6.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG10042.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG10042.1 - 0.14 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.8 OAG10043.1 - 1.6e-09 37.1 0.9 1.2e-08 34.2 0.9 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTP1_C2 PF10304.9 OAG10043.1 - 0.23 11.2 0.7 0.49 10.1 0.1 1.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 adh_short PF00106.25 OAG10044.1 - 1e-21 77.3 0.4 9.4e-20 70.9 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG10044.1 - 8e-14 51.9 0.2 1.2e-13 51.3 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG10044.1 - 1.9e-10 40.7 0.5 6.8e-10 38.9 0.2 1.8 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF3852 PF12963.7 OAG10044.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) HET PF06985.11 OAG10045.1 - 3.9e-27 95.4 0.0 4.5e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 OAG10045.1 - 0.17 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CUE PF02845.16 OAG10046.1 - 2.5e-06 27.1 0.0 5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain EptA_B_N PF08019.12 OAG10050.1 - 0.0024 17.8 1.0 0.66 9.8 0.0 2.2 1 1 1 2 2 2 2 Phosphoethanolamine transferase EptA/EptB DUF1218 PF06749.12 OAG10050.1 - 0.098 13.2 0.6 0.098 13.2 0.6 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) YwiC PF14256.6 OAG10050.1 - 1.8 8.9 7.2 0.17 12.2 1.2 2.1 2 1 0 2 2 2 0 YwiC-like protein ERG2_Sigma1R PF04622.12 OAG10052.1 - 6.6e-96 319.6 1.8 7.7e-96 319.4 1.8 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 OAG10052.1 - 0.064 13.2 0.8 1.4 8.9 0.3 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein OTU PF02338.19 OAG10053.1 - 1.9e-12 47.8 0.6 3.8e-12 46.8 0.6 1.4 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAG10053.1 - 0.013 15.0 0.1 2.8 7.3 0.0 2.5 1 1 1 2 2 2 0 Peptidase C65 Otubain TRAPPC-Trs85 PF12739.7 OAG10054.1 - 2.5e-108 362.7 0.1 3.6e-108 362.1 0.1 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Tti2 PF10521.9 OAG10055.1 - 7e-37 127.5 0.1 3.9e-36 125.0 0.1 2.0 1 1 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 OAG10055.1 - 1.1e-22 80.8 0.6 3.6e-22 79.1 0.6 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OAG10055.1 - 2.4e-07 30.4 0.3 8.6e-07 28.6 0.1 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 OAG10055.1 - 1.2e-06 28.6 0.0 2.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative PAM2 PF07145.15 OAG10057.1 - 0.00076 19.0 0.3 0.00076 19.0 0.3 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region EamA PF00892.20 OAG10058.1 - 0.00062 19.9 18.8 0.011 15.9 18.8 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 OAG10058.1 - 0.18 11.9 3.2 0.28 11.2 2.9 1.4 1 1 0 1 1 1 0 Putative transmembrane family 234 Trp_oprn_chp PF09534.10 OAG10058.1 - 0.28 11.0 4.4 0.97 9.2 0.9 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MoCF_biosynth PF00994.24 OAG10059.1 - 1.3e-52 177.2 0.1 2.2e-27 95.5 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 OAG10059.1 - 3.3e-40 137.4 2.2 5.2e-40 136.8 2.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) ATP-synt_C PF00137.21 OAG10059.1 - 3.9e-23 81.6 35.7 2e-14 53.6 11.4 3.1 3 0 0 3 3 3 2 ATP synthase subunit C MoeA_C PF03454.15 OAG10059.1 - 6e-16 58.4 0.1 1.5e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 OAG10059.1 - 9.6 5.5 8.7 15 4.9 8.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA_gamma_C PF02751.14 OAG10060.1 - 6.4e-25 87.0 3.5 1.2e-24 86.1 3.5 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 OAG10060.1 - 5e-23 80.9 0.1 6.8e-23 80.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFCD_C PF12612.8 OAG10062.1 - 8.9e-24 84.4 2.9 2.1e-21 76.6 1.1 3.2 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 OAG10062.1 - 0.00013 22.3 1.8 0.13 12.7 0.1 4.0 3 0 0 3 3 3 2 HEAT repeats IFRD PF05004.13 OAG10062.1 - 0.0025 17.0 1.2 0.0025 17.0 1.2 3.1 4 0 0 4 4 4 1 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 OAG10062.1 - 0.015 15.8 0.0 0.079 13.6 0.0 2.3 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAG10062.1 - 0.63 10.4 16.2 4.9 7.7 0.0 7.2 8 0 0 8 8 8 0 HEAT repeat CDC27 PF09507.10 OAG10063.1 - 3.4e-84 283.7 27.1 1.6e-83 281.5 27.1 1.8 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 ETX_MTX2 PF03318.13 OAG10064.1 - 5.9e-08 32.8 9.1 7.4e-08 32.4 9.1 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 MspA PF09203.11 OAG10064.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 MspA Aerolysin PF01117.20 OAG10064.1 - 0.065 12.4 3.1 0.094 11.9 3.1 1.2 1 0 0 1 1 1 0 Aerolysin toxin Pyridox_oxase_2 PF12766.7 OAG10065.1 - 1.7e-26 92.8 0.0 3.7e-26 91.6 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Lipase_GDSL_2 PF13472.6 OAG10068.1 - 3.8e-14 53.5 0.2 6.3e-14 52.8 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG10068.1 - 5.5e-09 36.3 0.0 6.5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 OAG10068.1 - 1.3e-05 25.4 0.0 1.8e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ETC_C1_NDUFA4 PF04800.12 OAG10070.1 - 1.5e-35 121.3 1.8 2.5e-35 120.6 1.8 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 OAG10071.1 - 1e-41 141.3 0.4 1.2e-41 141.1 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi LEA_3 PF03242.13 OAG10074.1 - 0.65 10.8 3.6 10 6.9 0.3 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein TPR_10 PF13374.6 OAG10075.1 - 2.3e-125 405.6 28.0 3.7e-12 45.7 0.0 12.1 12 0 0 12 12 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 OAG10075.1 - 3.9e-94 309.0 28.0 1.3e-16 60.6 0.1 9.8 2 1 9 11 11 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 OAG10075.1 - 2e-41 137.0 15.4 0.0012 18.7 0.0 11.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAG10075.1 - 2e-23 80.6 15.2 0.31 11.3 0.0 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG10075.1 - 2.4e-22 77.8 8.0 0.71 9.8 0.0 10.8 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAG10075.1 - 1.1e-16 59.9 13.0 1.2 9.7 0.0 10.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAG10075.1 - 3.9e-16 59.3 4.2 0.23 12.0 0.0 9.6 2 2 7 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG10075.1 - 1.2e-12 48.2 7.5 0.6 10.8 0.0 10.5 6 4 2 8 8 8 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAG10075.1 - 1.8e-11 43.7 0.2 2.3e-10 40.1 0.0 2.8 3 0 0 3 3 2 1 NB-ARC domain PPR PF01535.20 OAG10075.1 - 6e-10 38.7 1.7 21 5.7 0.0 9.8 10 0 0 10 10 10 0 PPR repeat TPR_4 PF07721.14 OAG10075.1 - 3.1e-06 27.3 31.0 1.8 9.4 0.1 10.4 12 0 0 12 12 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG10075.1 - 1.4e-05 25.0 10.5 1.3 9.4 0.1 8.7 11 0 0 11 11 9 1 Tetratricopeptide repeat AAA_22 PF13401.6 OAG10075.1 - 2.1e-05 24.8 0.6 0.00023 21.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG10075.1 - 0.00057 20.3 0.2 0.00057 20.3 0.2 3.1 3 1 0 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OAG10075.1 - 0.0028 17.4 1.3 0.02 14.6 0.0 3.1 4 0 0 4 4 2 1 IstB-like ATP binding protein Urocanase_N PF17391.2 OAG10075.1 - 0.0057 16.3 1.8 22 4.7 0.0 6.2 7 2 2 9 9 8 0 Urocanase N-terminal domain TniB PF05621.11 OAG10075.1 - 0.0068 15.8 0.0 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein TPR_14 PF13428.6 OAG10075.1 - 0.0085 16.8 25.7 1 10.4 0.0 10.7 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_3 PF07720.12 OAG10075.1 - 0.013 15.4 2.1 20 5.3 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN6_N PF18055.1 OAG10075.1 - 0.016 15.5 5.0 11 6.4 0.0 5.1 4 1 2 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain ORC4_C PF14629.6 OAG10075.1 - 0.018 14.4 0.4 0.037 13.4 0.4 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus ATPase_2 PF01637.18 OAG10075.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 OAG10075.1 - 0.042 14.3 0.0 0.21 12.0 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OAG10075.1 - 0.056 12.7 0.6 8.6 5.6 0.2 2.9 2 1 1 3 3 3 0 Zeta toxin DUF1571 PF07608.11 OAG10075.1 - 0.33 10.4 5.7 3.1 7.2 0.3 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF1571) TPR_20 PF14561.6 OAG10075.1 - 0.44 10.9 18.5 5.5 7.4 0.0 8.2 4 1 8 12 12 10 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG10075.1 - 0.47 10.7 8.3 3 8.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-Mss51 PF13824.6 OAG10075.1 - 1 9.5 8.7 1.5e+02 2.6 0.0 6.3 8 0 0 8 8 6 0 Zinc-finger of mitochondrial splicing suppressor 51 N1221 PF07923.13 OAG10075.1 - 1.2 8.2 8.8 6 6.0 0.5 3.9 2 1 0 4 4 4 0 N1221-like protein TPR_6 PF13174.6 OAG10075.1 - 8.3 7.3 25.3 13 6.7 0.0 9.6 11 0 0 11 11 10 0 Tetratricopeptide repeat Glyco_hydro_79C PF16862.5 OAG10076.1 - 4e-18 66.2 3.4 6.6e-17 62.3 2.6 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain AMP-binding PF00501.28 OAG10077.1 - 5.2e-15 55.0 0.2 1.8e-09 36.7 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme TctB PF07331.11 OAG10078.1 - 6.6 7.0 21.6 5.6 7.2 11.6 2.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family CM_2 PF01817.21 OAG10079.1 - 4e-06 27.1 0.0 5.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Chorismate mutase type II FMO-like PF00743.19 OAG10080.1 - 5.8e-59 199.9 0.0 9.9e-59 199.1 0.0 1.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG10080.1 - 8.9e-11 41.6 0.0 6.1e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG10080.1 - 5.9e-08 32.3 0.0 1.6e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG10080.1 - 1.7e-07 31.3 0.0 5.3e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG10080.1 - 1.3e-06 27.8 0.3 0.00011 21.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG10080.1 - 0.00014 21.9 0.1 0.036 14.1 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG10080.1 - 0.0042 16.5 0.1 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG10080.1 - 0.0043 17.2 0.0 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 OAG10080.1 - 0.0046 16.2 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OAG10080.1 - 0.0078 16.7 0.0 0.078 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG10080.1 - 0.012 15.2 0.0 3.3 7.2 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase IlvN PF07991.12 OAG10080.1 - 0.028 14.0 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 OAG10080.1 - 0.17 12.3 0.0 2.1 8.8 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAG10080.1 - 0.21 10.8 0.1 0.41 9.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 OAG10080.1 - 0.26 11.3 0.3 11 6.0 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Aldo_ket_red PF00248.21 OAG10081.1 - 1.2e-10 41.1 0.0 1.5e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 OAG10082.1 - 3.9e-51 172.7 1.3 6.7e-51 172.0 1.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.10 OAG10082.1 - 1.5e-46 158.7 0.0 2.3e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator TerB_C PF15615.6 OAG10086.1 - 4.8 7.5 6.4 0.62 10.4 0.7 2.5 3 0 0 3 3 3 0 TerB-C domain AAA_13 PF13166.6 OAG10087.1 - 0.00022 20.0 24.3 0.00022 20.0 24.3 3.1 2 1 1 3 3 3 1 AAA domain TMF_DNA_bd PF12329.8 OAG10087.1 - 0.0056 16.7 15.0 0.0056 16.7 15.0 6.6 5 2 0 5 5 5 2 TATA element modulatory factor 1 DNA binding HAUS-augmin3 PF14932.6 OAG10087.1 - 0.0088 15.6 13.8 0.0088 15.6 13.8 3.9 2 1 2 4 4 4 1 HAUS augmin-like complex subunit 3 BST2 PF16716.5 OAG10087.1 - 0.013 16.0 7.6 0.013 16.0 7.6 6.5 4 1 2 7 7 7 0 Bone marrow stromal antigen 2 KASH_CCD PF14662.6 OAG10087.1 - 0.028 14.2 51.5 0.14 11.9 26.9 3.9 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 OAG10087.1 - 2.9 8.1 41.1 0.083 13.1 9.5 5.7 2 1 3 5 5 5 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 OAG10087.1 - 4.4 7.4 20.5 0.19 11.8 6.1 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Sugarporin_N PF11471.8 OAG10087.1 - 5.8 6.9 28.1 0.043 13.8 3.8 4.7 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension DUF4648 PF15505.6 OAG10087.1 - 8.5 7.3 10.7 7.9 7.4 0.6 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4648) adh_short_C2 PF13561.6 OAG10088.1 - 1.7e-53 181.6 0.3 2.3e-53 181.2 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG10088.1 - 2.8e-45 154.2 1.8 3.5e-45 153.9 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG10088.1 - 4.6e-12 46.2 0.4 6e-12 45.8 0.4 1.1 1 0 0 1 1 1 1 KR domain N6_Mtase PF02384.16 OAG10088.1 - 0.0068 15.7 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase CABS1 PF15367.6 OAG10088.1 - 0.014 14.5 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 AdoHcyase_NAD PF00670.21 OAG10088.1 - 0.021 14.9 2.3 0.038 14.1 2.3 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TIR PF01582.20 OAG10088.1 - 0.088 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 TIR domain 3HCDH_N PF02737.18 OAG10088.1 - 0.12 12.3 0.7 0.2 11.5 0.5 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SurE PF01975.17 OAG10089.1 - 3.7e-52 176.9 0.0 5e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE NAD_binding_8 PF13450.6 OAG10090.1 - 4.9e-10 39.5 0.2 1.3e-09 38.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG10090.1 - 3.4e-07 29.7 2.9 4.4e-07 29.3 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAG10090.1 - 6e-07 29.2 1.1 7.4e-07 28.9 0.3 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG10090.1 - 6.3e-07 29.0 0.0 2.6e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 OAG10090.1 - 5.3e-06 26.3 1.2 1e-05 25.3 1.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG10090.1 - 2.7e-05 23.6 0.2 7.4e-05 22.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG10090.1 - 0.00019 20.3 0.2 0.00026 19.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 OAG10090.1 - 0.00026 21.5 0.3 0.00064 20.2 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG10090.1 - 0.00068 18.9 0.3 0.0013 18.0 0.3 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG10090.1 - 0.0072 15.6 0.2 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG10090.1 - 0.037 12.9 0.3 0.059 12.2 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG10090.1 - 0.052 12.8 0.1 0.091 12.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG10090.1 - 0.053 12.6 0.2 0.075 12.1 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4141 PF13605.6 OAG10091.1 - 0.047 12.9 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Fmp27 PF10344.9 OAG10092.1 - 1.1e-210 702.0 0.0 1.9e-210 701.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 OAG10092.1 - 8.7e-184 611.8 0.6 8.7e-184 611.8 0.6 3.4 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 OAG10092.1 - 5.5e-173 576.3 4.2 5.5e-173 576.3 4.2 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 OAG10092.1 - 6.6e-59 198.5 0.0 1.8e-58 197.1 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 OAG10092.1 - 4.7e-56 189.0 0.4 1.3e-55 187.5 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 OAG10092.1 - 1.5e-31 109.1 0.6 9.2e-31 106.6 0.0 2.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF1749 PF08538.10 OAG10093.1 - 1.4e-75 254.2 0.0 1.8e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OAG10093.1 - 2.5e-05 25.0 0.1 3.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 OAG10093.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 OAG10093.1 - 0.055 12.7 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAG10093.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.16 OAG10093.1 - 0.21 11.4 0.0 8.7 6.1 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Syntaxin PF00804.25 OAG10094.1 - 5.4e-19 68.7 8.4 5.4e-19 68.7 8.4 1.9 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 OAG10094.1 - 4.4e-10 39.4 0.3 1e-09 38.2 0.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 OAG10094.1 - 2.3e-05 24.7 9.4 2.3e-05 24.7 9.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein DUF677 PF05055.12 OAG10094.1 - 0.0059 15.5 1.3 0.27 10.1 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF677) DUF2951 PF11166.8 OAG10094.1 - 0.075 13.3 0.1 0.075 13.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Lebercilin PF15619.6 OAG10094.1 - 0.14 11.8 16.0 0.11 12.1 3.7 3.2 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Vac_Fusion PF02346.16 OAG10094.1 - 0.15 11.7 0.6 0.58 9.8 0.4 2.1 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 ZYG-11_interact PF05884.12 OAG10094.1 - 0.19 11.1 0.1 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 Interactor of ZYG-11 LPP PF04728.13 OAG10094.1 - 0.28 11.6 7.8 0.85 10.1 0.5 4.0 3 1 0 3 3 3 0 Lipoprotein leucine-zipper MCU PF04678.13 OAG10094.1 - 0.4 10.8 9.9 4.6 7.3 9.9 2.3 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Synaptobrevin PF00957.21 OAG10094.1 - 0.64 9.8 6.3 0.17 11.7 1.1 2.3 2 0 0 2 2 2 0 Synaptobrevin DUF16 PF01519.16 OAG10094.1 - 3.3 8.2 15.0 0.39 11.2 3.1 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 OAG10094.1 - 6.2 7.5 13.0 0.54 10.9 5.7 2.8 2 1 0 2 2 2 0 SlyX Glyco_hydro_72 PF03198.14 OAG10095.1 - 2.6e-125 417.9 4.0 3.2e-125 417.6 4.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase MMR_HSR1_C PF08438.10 OAG10096.1 - 7.3e-37 126.4 0.0 1.4e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 OAG10096.1 - 5.1e-20 71.7 0.0 1.2e-19 70.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG10096.1 - 5.2e-09 35.8 0.1 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG10096.1 - 0.0027 17.3 0.0 0.51 9.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OAG10096.1 - 0.0062 16.3 0.2 1.3 8.8 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 OAG10096.1 - 0.037 14.1 1.0 0.14 12.2 0.2 2.2 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 OAG10096.1 - 0.04 14.4 0.0 0.66 10.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 OAG10096.1 - 0.079 12.9 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1_Xtn PF16897.5 OAG10096.1 - 0.082 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain KTI12 PF08433.10 OAG10096.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 OAG10096.1 - 0.13 12.1 0.6 4.8 7.1 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Actin PF00022.19 OAG10099.1 - 8.2e-113 377.1 0.0 5.6e-112 374.3 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAG10099.1 - 0.061 12.1 0.0 0.33 9.7 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein Ribosomal_L5e PF17144.4 OAG10100.1 - 1.9e-39 135.3 0.0 3.5e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OAG10100.1 - 1.6e-35 121.9 7.9 2.2e-35 121.5 7.9 1.2 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 OAG10100.1 - 0.031 14.5 0.0 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 Threonine synthase N terminus DUF3135 PF11333.8 OAG10101.1 - 0.015 15.6 0.1 0.48 10.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) CDC45 PF02724.14 OAG10101.1 - 0.4 8.9 7.8 0.8 7.9 7.8 1.5 1 0 0 1 1 1 0 CDC45-like protein LRR_4 PF12799.7 OAG10101.1 - 7.9 7.1 6.7 1.2e+02 3.3 0.6 4.6 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) FliD_N PF02465.18 OAG10103.1 - 0.02 15.6 1.1 2.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HhH-GPD PF00730.25 OAG10104.1 - 8.3e-20 71.3 0.0 1.7e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG10104.1 - 1e-07 31.5 0.0 3.4e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif FdhD-NarQ PF02634.15 OAG10104.1 - 0.012 15.4 1.5 0.018 14.8 0.1 2.0 2 1 1 3 3 3 0 FdhD/NarQ family Calpain_inhib PF00748.19 OAG10104.1 - 0.014 15.9 3.2 0.014 15.9 3.2 2.2 2 1 0 2 2 2 0 Calpain inhibitor DUF2187 PF09953.9 OAG10104.1 - 0.074 13.1 1.2 0.17 11.9 1.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) AAA_11 PF13086.6 OAG10105.1 - 7e-61 206.3 0.1 1.5e-60 205.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 OAG10105.1 - 1.5e-56 191.2 0.0 1.3e-55 188.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG10105.1 - 7e-12 45.5 0.0 9.5e-11 41.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG10105.1 - 3.6e-10 40.3 0.0 5e-09 36.6 0.0 2.9 3 1 0 3 3 3 1 AAA domain UvrD_C PF13361.6 OAG10105.1 - 3.8e-06 26.5 0.0 1.3 8.3 0.0 3.5 3 1 0 3 3 3 3 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OAG10105.1 - 4.2e-06 26.7 0.0 0.26 11.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAG10105.1 - 5e-06 26.3 0.2 8.3e-05 22.3 0.1 2.5 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 OAG10105.1 - 1.9e-05 24.7 0.0 6.5e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OAG10105.1 - 1.9e-05 24.1 0.5 0.00012 21.5 0.5 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OAG10105.1 - 5.9e-05 22.6 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD_C_2 PF13538.6 OAG10105.1 - 9.5e-05 22.1 0.0 0.2 11.5 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 OAG10105.1 - 0.00022 21.5 0.1 0.0013 19.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG10105.1 - 0.00023 21.6 0.1 0.00059 20.3 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 OAG10105.1 - 0.00064 19.6 0.0 0.046 13.6 0.0 2.7 1 1 0 1 1 1 1 Helicase DEAD PF00270.29 OAG10105.1 - 0.0017 18.2 0.1 0.014 15.2 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 OAG10105.1 - 0.0046 16.9 0.6 0.012 15.6 0.0 2.0 3 0 0 3 3 1 1 Flavivirus DEAD domain T2SSE PF00437.20 OAG10105.1 - 0.0048 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.14 OAG10105.1 - 0.015 15.3 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OAG10105.1 - 0.017 15.5 0.1 0.047 14.1 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 4HB_MCP_1 PF12729.7 OAG10105.1 - 0.019 14.5 0.4 0.042 13.4 0.4 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ABC_tran PF00005.27 OAG10105.1 - 0.062 13.8 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 OAG10105.1 - 0.069 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAG10105.1 - 0.072 12.8 0.0 0.3 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG10105.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 OAG10105.1 - 0.17 12.4 4.0 1.3 9.4 0.0 2.5 1 1 0 2 2 2 0 AAA domain Lzipper-MIP1 PF14389.6 OAG10106.1 - 0.036 14.3 0.1 1.1 9.6 0.0 2.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 EzrA PF06160.12 OAG10106.1 - 0.056 11.6 0.1 0.12 10.5 0.0 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CLZ PF16526.5 OAG10106.1 - 0.063 13.7 0.9 1.9 8.9 0.0 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Hsk3 PF08227.11 OAG10106.1 - 0.067 13.6 3.7 2.7 8.4 0.2 3.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF2205 PF10224.9 OAG10106.1 - 0.092 12.8 4.3 0.86 9.6 0.5 3.0 2 1 1 3 3 3 0 Short coiled-coil protein APG6_N PF17675.1 OAG10106.1 - 0.1 13.1 0.2 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region XkdW PF09636.10 OAG10106.1 - 0.1 12.7 0.3 0.56 10.3 0.0 2.4 3 0 0 3 3 3 0 XkdW protein betaPIX_CC PF16523.5 OAG10106.1 - 0.13 12.1 0.3 0.87 9.5 0.0 2.3 2 0 0 2 2 2 0 betaPIX coiled coil Tmemb_cc2 PF10267.9 OAG10106.1 - 0.6 9.2 5.0 1.4 8.0 5.0 1.7 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Myosin_tail_1 PF01576.19 OAG10106.1 - 1.1 7.0 3.5 0.76 7.5 0.1 1.9 2 0 0 2 2 2 0 Myosin tail SKA1 PF07160.12 OAG10106.1 - 1.8 8.4 4.3 17 5.2 0.7 2.7 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Trimer_CC PF08954.11 OAG10106.1 - 3.1 7.4 7.8 0.51 9.9 0.3 3.7 4 0 0 4 4 4 0 Trimerisation motif 7TM_GPCR_Srsx PF10320.9 OAG10107.1 - 4.4e-07 29.6 4.3 7.9e-07 28.7 4.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Reticulon PF02453.17 OAG10107.1 - 0.054 13.5 0.3 0.054 13.5 0.3 3.5 5 0 0 5 5 5 0 Reticulon DUF4271 PF14093.6 OAG10107.1 - 0.49 10.3 15.1 0.073 13.0 5.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) TMEM132D_C PF15706.5 OAG10107.1 - 9.6 6.1 6.7 3.1e+02 1.2 6.7 2.7 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term GATase PF00117.28 OAG10108.1 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Chitin_synth_2 PF03142.15 OAG10108.1 - 0.2 10.3 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase DIOX_N PF14226.6 OAG10109.1 - 9.4e-20 71.5 0.0 1.3e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG10109.1 - 7.3e-18 64.9 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG10110.1 - 5.2e-14 51.9 50.7 1.5e-09 37.3 12.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG10110.1 - 0.0012 17.4 19.7 0.002 16.6 19.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PBP PF01161.20 OAG10112.1 - 2.7e-09 37.4 0.0 5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CAP_N PF01213.19 OAG10112.1 - 7.5 5.9 9.3 3.6 7.0 5.9 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_L4 PF00573.22 OAG10113.1 - 4.9e-44 150.3 0.0 8.7e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family MscS_porin PF12795.7 OAG10113.1 - 0.00015 21.4 1.9 0.00015 21.4 1.9 2.3 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Med9 PF07544.13 OAG10113.1 - 1.5 9.0 7.1 0.38 10.9 3.1 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LUC7 PF03194.15 OAG10113.1 - 9.4 5.8 17.0 0.44 10.2 8.5 2.1 1 1 1 2 2 2 0 LUC7 N_terminus JAB PF01398.21 OAG10114.1 - 2.4e-29 101.7 0.0 4.2e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 OAG10114.1 - 7.5e-17 62.0 0.1 2.5e-16 60.4 0.1 1.9 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 OAG10114.1 - 2.8e-06 27.1 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 OAG10114.1 - 0.0078 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) ATG16 PF08614.11 OAG10115.1 - 2.1e-34 119.5 22.4 2.4e-34 119.3 22.4 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Trehalase PF01204.18 OAG10115.1 - 0.0047 15.8 4.8 0.0075 15.1 4.8 1.3 1 0 0 1 1 1 1 Trehalase Lebercilin PF15619.6 OAG10115.1 - 0.0072 16.0 22.3 0.0072 16.0 22.3 1.9 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease SPT16 PF08644.11 OAG10115.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.8 2 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) Herpes_UL6 PF01763.16 OAG10115.1 - 0.13 10.8 7.1 0.17 10.4 7.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.19 OAG10115.1 - 0.65 7.8 14.0 0.8 7.5 14.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 OAG10115.1 - 0.86 8.6 12.2 1.3 8.0 12.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup88 PF10168.9 OAG10115.1 - 4 5.1 20.6 5.1 4.8 20.6 1.1 1 0 0 1 1 1 0 Nuclear pore component SlyX PF04102.12 OAG10115.1 - 7.4 7.3 14.8 7.6 7.2 7.3 3.0 1 1 2 3 3 3 0 SlyX IF3_C PF00707.22 OAG10116.1 - 6.3e-08 32.5 0.9 3.1e-05 23.8 0.2 2.4 2 0 0 2 2 2 2 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 OAG10116.1 - 4.5e-05 23.6 0.0 8.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 OAG10116.1 - 8.4e-05 22.3 0.1 0.085 12.5 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial translation initiation factor 2OG-FeII_Oxy PF03171.20 OAG10117.1 - 5.7e-13 49.2 0.0 1e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG10117.1 - 2.5e-07 31.5 0.0 3.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_M20 PF01546.28 OAG10119.1 - 8.2e-07 28.9 0.0 2.1e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG10119.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.9 1 0 0 1 1 1 0 Peptidase dimerisation domain DUF2309 PF10070.9 OAG10119.1 - 0.23 9.8 0.1 0.31 9.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) YjeF_N PF03853.15 OAG10120.1 - 7.3e-40 136.6 0.1 1.2e-39 135.9 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Transglut_core PF01841.19 OAG10120.1 - 1e-11 45.3 0.0 2.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily FDF PF09532.10 OAG10120.1 - 0.00016 22.5 0.4 0.00016 22.5 0.4 2.4 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.7 OAG10120.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain Gln_amidase PF15644.6 OAG10120.1 - 0.036 15.1 0.7 0.16 13.0 0.0 2.5 2 0 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase DUF553 PF04473.12 OAG10120.1 - 0.087 12.3 0.0 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 Transglutaminase-like domain CHZ PF09649.10 OAG10121.1 - 0.00078 18.9 0.1 0.00078 18.9 0.1 2.5 2 0 0 2 2 2 1 Histone chaperone domain CHZ Zn_clus PF00172.18 OAG10121.1 - 0.00088 19.3 11.5 0.0017 18.5 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 OAG10122.1 - 2e-44 150.4 0.6 5.5e-44 149.0 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG10122.1 - 1.7e-34 118.5 0.1 3.7e-34 117.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pox_LP_H2 PF03356.15 OAG10124.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral late protein H2 TPR_21 PF09976.9 OAG10124.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain PikAIV_N PF18605.1 OAG10125.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ribosomal_L7Ae PF01248.26 OAG10126.1 - 3.9e-26 90.6 0.0 4.6e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAG10126.1 - 7.6e-05 22.5 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 OAG10126.1 - 0.00023 21.3 0.2 0.00041 20.4 0.2 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 DUF639 PF04842.12 OAG10126.1 - 0.046 13.1 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) ATP-synt_C PF00137.21 OAG10127.1 - 1e-34 118.6 35.7 1.7e-21 76.3 15.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Peptidase_M14 PF00246.24 OAG10128.1 - 1.5e-81 274.4 0.2 1.8e-81 274.1 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase GFO_IDH_MocA PF01408.22 OAG10129.1 - 8.5e-23 81.5 0.0 1.6e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG10129.1 - 0.0015 18.5 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NIR_SIR PF01077.22 OAG10131.1 - 1.4e-52 177.4 0.0 9.4e-48 161.7 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OAG10131.1 - 1.9e-30 104.5 0.0 9.6e-14 51.0 0.0 2.9 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 OAG10131.1 - 3.1e-27 95.6 0.0 7e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 OAG10131.1 - 6.2e-11 42.5 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PAPS_reduct PF01507.19 OAG10132.1 - 3e-29 102.3 0.0 3.8e-20 72.6 0.0 2.4 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Wyosine_form PF08608.12 OAG10133.1 - 3.9e-23 81.6 0.0 8.8e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 OAG10133.1 - 2.7e-19 70.2 0.0 8.6e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 OAG10133.1 - 5.7e-09 36.3 0.1 9.8e-08 32.3 0.1 2.5 1 1 0 1 1 1 1 Flavodoxin OB_NTP_bind PF07717.16 OAG10133.1 - 0.14 12.5 0.1 0.39 11.1 0.0 1.7 2 0 0 2 2 2 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Pkinase PF00069.25 OAG10134.1 - 4.3e-48 164.0 0.0 5.7e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG10134.1 - 4.9e-29 101.4 0.0 6.2e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG10134.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG10134.1 - 0.00048 19.5 0.1 0.0025 17.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OAG10134.1 - 0.0063 16.1 0.0 0.022 14.3 0.0 1.8 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OAG10134.1 - 0.027 14.4 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TAD2 PF18521.1 OAG10135.1 - 0.35 10.9 1.9 25 5.1 0.1 2.7 2 0 0 2 2 2 0 Transactivation domain 2 Pro_dh PF01619.18 OAG10136.1 - 2.9e-61 207.6 0.6 3.7e-61 207.3 0.6 1.0 1 0 0 1 1 1 1 Proline dehydrogenase DUF3112 PF11309.8 OAG10137.1 - 1.7e-09 37.5 6.2 5.3e-06 26.1 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) DUF2177 PF09945.9 OAG10137.1 - 0.037 14.1 6.0 0.56 10.3 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) GWT1 PF06423.12 OAG10137.1 - 0.19 11.8 4.5 0.39 10.8 4.5 1.5 1 0 0 1 1 1 0 GWT1 Ion_trans PF00520.31 OAG10139.1 - 5.9e-05 22.4 13.1 0.00014 21.1 13.1 1.6 1 0 0 1 1 1 1 Ion transport protein zf-C2H2 PF00096.26 OAG10140.1 - 1e-11 44.6 18.9 0.0022 18.4 2.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG10140.1 - 1.8e-09 37.7 14.9 0.01 16.6 0.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG10140.1 - 6.5e-06 26.3 1.1 6.5e-06 26.3 1.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG10140.1 - 0.00077 19.7 8.5 0.85 10.0 0.4 3.6 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG10140.1 - 0.0036 17.6 3.9 0.33 11.4 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OAG10140.1 - 0.028 14.2 0.1 0.028 14.2 0.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-BED PF02892.15 OAG10140.1 - 1.4 9.0 9.4 5.7 7.0 0.8 3.3 1 1 2 3 3 3 0 BED zinc finger PI31_Prot_N PF11566.8 OAG10141.1 - 2.5e-51 173.7 0.0 3.1e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 OAG10141.1 - 1.1e-17 64.9 20.6 1.1e-17 64.9 20.6 2.6 2 1 0 2 2 2 1 PI31 proteasome regulator Cupin_8 PF13621.6 OAG10143.1 - 1.8e-39 136.0 0.0 2.6e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 OAG10143.1 - 6.3e-23 81.7 0.0 9.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 OAG10143.1 - 9.4e-18 64.0 0.2 5.5e-06 26.3 0.1 4.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG10143.1 - 3.3e-07 30.4 0.8 0.0053 17.0 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Cupin_4 PF08007.12 OAG10143.1 - 4.3e-06 26.4 0.0 8.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.6 OAG10143.1 - 4.5e-06 26.5 0.0 0.0057 16.6 0.0 4.3 4 0 0 4 4 4 1 Kelch motif JmjC PF02373.22 OAG10143.1 - 0.15 12.5 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase ANAPC4_WD40 PF12894.7 OAG10144.1 - 5.2e-05 23.5 0.0 1.3 9.4 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG10144.1 - 0.00054 20.7 0.0 0.12 13.2 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DSPc PF00782.20 OAG10145.1 - 7.5e-28 97.0 0.0 1.3e-20 73.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG10145.1 - 0.00019 21.1 0.0 0.0031 17.1 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG10145.1 - 0.17 12.0 0.0 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate DNA_pol_delta_4 PF04081.13 OAG10147.1 - 1e-34 119.7 4.4 2e-34 118.7 4.4 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Clostridium_P47 PF06597.11 OAG10147.1 - 0.14 10.9 1.0 0.18 10.5 1.0 1.1 1 0 0 1 1 1 0 Clostridium P-47 protein DcpS PF05652.12 OAG10148.1 - 1.9e-33 115.4 0.0 3e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 OAG10148.1 - 4.9e-28 97.9 0.0 7.9e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GDP_Man_Dehyd PF16363.5 OAG10149.1 - 3.1e-48 164.9 0.0 4.7e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG10149.1 - 4.7e-46 157.2 0.0 6e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG10149.1 - 3.5e-16 59.0 0.0 2.3e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG10149.1 - 1.2e-13 50.8 0.2 4e-12 45.9 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG10149.1 - 2.9e-11 43.0 0.0 4.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OAG10149.1 - 1e-08 34.9 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG10149.1 - 9.4e-06 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 OAG10149.1 - 4.2e-05 22.8 0.1 0.0014 17.9 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG10149.1 - 0.00029 20.8 0.0 0.00042 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 OAG10149.1 - 0.0097 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 OAG10149.1 - 0.026 14.1 0.0 0.066 12.8 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 OAG10149.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain tRNA_bind PF01588.20 OAG10150.1 - 5e-22 77.8 0.0 1.5e-21 76.3 0.0 1.9 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 OAG10150.1 - 3.5e-05 23.7 0.0 7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG10150.1 - 0.0033 17.6 0.2 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Med3 PF11593.8 OAG10150.1 - 1.2 8.2 8.6 2 7.5 8.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_C12 PF01088.21 OAG10151.1 - 1.3e-55 188.4 0.0 1.5e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Git3 PF11710.8 OAG10152.1 - 5.7e-53 179.7 8.3 5.7e-53 179.7 8.3 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 OAG10152.1 - 4.9e-27 93.8 2.6 1.2e-26 92.6 2.6 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term TPR_12 PF13424.6 OAG10153.1 - 2.7e-16 59.6 9.4 0.27 11.6 0.1 8.5 9 0 0 9 9 8 5 Tetratricopeptide repeat AAA_22 PF13401.6 OAG10153.1 - 3.7e-07 30.5 4.0 5.9e-07 29.8 0.0 3.5 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 OAG10153.1 - 4.2e-07 30.0 0.0 1.6e-06 28.2 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG10153.1 - 2.6e-06 27.9 0.0 2.6e-06 27.9 0.0 4.4 4 1 1 5 5 3 1 AAA ATPase domain TPR_7 PF13176.6 OAG10153.1 - 7.1e-05 22.6 1.6 6 7.1 0.0 8.0 9 0 0 9 9 7 1 Tetratricopeptide repeat AAA PF00004.29 OAG10153.1 - 0.00093 19.6 0.0 0.0067 16.8 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAG10153.1 - 0.0016 18.4 0.1 0.0088 16.0 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea BCDHK_Adom3 PF10436.9 OAG10153.1 - 0.023 14.5 0.0 0.18 11.6 0.0 2.5 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase RNA_helicase PF00910.22 OAG10153.1 - 0.03 14.7 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 OAG10153.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 OAG10153.1 - 0.035 14.7 0.0 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OAG10153.1 - 0.036 14.1 0.2 0.23 11.5 0.0 2.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OAG10153.1 - 0.058 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5028 PF16431.5 OAG10153.1 - 0.071 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5028) ABC_tran PF00005.27 OAG10153.1 - 0.57 10.7 3.0 0.89 10.1 0.0 2.8 3 0 0 3 3 3 0 ABC transporter TPR_8 PF13181.6 OAG10153.1 - 1.9 8.9 7.4 66 4.1 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat GCN5L1 PF06320.13 OAG10153.1 - 2.5 8.3 9.1 4.4 7.5 0.5 3.5 3 1 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) ADH_zinc_N PF00107.26 OAG10154.1 - 1.1e-29 103.1 0.2 2.2e-29 102.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG10154.1 - 5.2e-18 66.4 0.1 1.1e-17 65.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG10154.1 - 1.8e-07 31.0 0.0 5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 OAG10154.1 - 0.00085 18.8 1.1 0.0091 15.5 0.3 2.0 1 1 1 2 2 2 1 short chain dehydrogenase ADH_N_2 PF16884.5 OAG10154.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 OAG10154.1 - 0.014 15.7 0.1 0.031 14.5 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain HTH_AsnC-type PF13404.6 OAG10155.1 - 0.0014 18.4 0.0 0.58 10.0 0.0 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain DUF908 PF06012.12 OAG10155.1 - 0.71 9.2 3.3 0.89 8.9 3.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ORC6 PF05460.13 OAG10155.1 - 4.6 6.4 8.5 6.2 6.0 8.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Exo84_C PF16528.5 OAG10156.1 - 1.5e-66 224.1 3.3 1.5e-66 224.1 3.3 2.3 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 OAG10156.1 - 6.6e-15 55.0 5.8 6.6e-15 55.0 5.8 2.2 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 OAG10156.1 - 0.0099 16.0 1.1 0.0099 16.0 1.1 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 VirD1 PF07328.11 OAG10156.1 - 0.018 15.0 0.5 0.073 13.0 0.0 2.0 2 0 0 2 2 2 0 T-DNA border endonuclease VirD1 ABC_tran_CTD PF16326.5 OAG10156.1 - 6.8 7.0 7.9 3.1 8.1 1.7 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain MAS20 PF02064.15 OAG10157.1 - 1.2e-49 167.6 0.8 1.5e-49 167.4 0.8 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Nif11 PF07862.11 OAG10157.1 - 0.0079 16.5 1.8 0.15 12.4 1.8 2.4 1 1 0 1 1 1 1 Nif11 domain GramPos_pilinD1 PF16555.5 OAG10157.1 - 0.011 15.9 0.4 0.016 15.4 0.4 1.1 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain PsbN PF02468.15 OAG10157.1 - 0.013 15.3 1.2 0.023 14.5 1.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) U1snRNP70_N PF12220.8 OAG10157.1 - 0.024 15.2 0.7 0.043 14.4 0.7 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Frankia_peptide PF14407.6 OAG10157.1 - 0.042 13.8 1.1 2.6 8.1 0.1 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DcuA_DcuB PF03605.14 OAG10157.1 - 0.088 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Sel_put PF04328.13 OAG10157.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Selenoprotein, putative AP-5_subunit_s1 PF15001.6 OAG10157.1 - 0.14 12.1 0.6 0.17 11.9 0.6 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF4199 PF13858.6 OAG10157.1 - 0.21 12.0 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ras PF00071.22 OAG10158.1 - 8.6e-60 201.0 0.7 1.1e-59 200.7 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG10158.1 - 4.7e-37 126.9 0.2 9e-37 126.0 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG10158.1 - 7.9e-18 64.5 0.5 9.9e-18 64.2 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG10158.1 - 1.3e-06 28.2 0.2 7.8e-06 25.6 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAG10158.1 - 5.8e-06 25.9 0.1 7.9e-06 25.4 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAG10158.1 - 1.5e-05 25.1 0.1 2.9e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG10158.1 - 1.9e-05 24.2 0.4 2.4e-05 23.8 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAG10158.1 - 2.3e-05 24.4 0.7 0.012 15.5 0.4 2.3 2 1 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 OAG10158.1 - 0.11 12.7 0.0 11 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Nop53 PF07767.11 OAG10159.1 - 9.4e-106 354.5 36.9 1.1e-105 354.3 36.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Sugar_tr PF00083.24 OAG10163.1 - 5e-111 371.7 18.7 5.7e-111 371.6 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10163.1 - 4e-27 95.1 30.8 9e-18 64.3 4.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG10163.1 - 4.6e-06 25.4 22.0 0.00057 18.5 0.1 3.0 2 1 0 3 3 3 2 MFS/sugar transport protein 4HBT_3 PF13622.6 OAG10164.1 - 2.4e-28 100.0 1.8 2.3e-27 96.8 1.8 2.0 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG10164.1 - 4.1e-07 29.9 0.6 0.1 12.5 0.0 4.0 3 1 0 3 3 3 3 Acyl-CoA thioesterase Glyco_hydro_67M PF07488.12 OAG10166.1 - 9.9e-150 498.1 0.1 1.5e-149 497.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 OAG10166.1 - 7.9e-89 297.0 3.3 1.2e-88 296.4 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 OAG10166.1 - 1.7e-30 105.8 0.0 3.1e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 OAG10166.1 - 0.00035 21.4 0.5 0.0012 19.6 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Ank_2 PF12796.7 OAG10167.1 - 2.5e-11 44.0 0.0 5e-09 36.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG10167.1 - 2.2e-10 40.8 0.0 0.0016 18.9 0.0 4.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG10167.1 - 2.5e-09 37.2 0.0 0.00018 21.8 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OAG10167.1 - 4.7e-08 33.2 0.0 7.8e-06 26.1 0.0 2.9 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG10167.1 - 1.7e-06 27.9 0.0 0.0016 18.8 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat p450 PF00067.22 OAG10169.1 - 5.1e-68 229.9 0.0 5.7e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 QSregVF_b PF12843.7 OAG10169.1 - 0.061 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Cupin_8 PF13621.6 OAG10169.1 - 0.063 13.0 0.2 0.59 9.8 0.0 2.4 3 0 0 3 3 3 0 Cupin-like domain DUF5564 PF17719.1 OAG10169.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5564) TRI12 PF06609.13 OAG10170.1 - 1.1e-42 146.2 22.0 1.4e-42 146.0 22.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG10170.1 - 4.5e-23 81.7 41.8 4.5e-23 81.7 41.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG10170.1 - 4e-11 42.4 11.8 4e-11 42.4 11.8 3.9 2 1 0 3 3 3 1 Sugar (and other) transporter Goodbye PF17109.5 OAG10172.1 - 3.3e-06 27.5 0.1 3.5e-06 27.5 0.1 1.0 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain ThiF PF00899.21 OAG10173.1 - 6.8e-110 366.2 0.0 2.2e-75 253.2 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OAG10173.1 - 1.3e-89 300.5 0.4 2.1e-89 299.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OAG10173.1 - 1.1e-30 105.6 0.0 2.3e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OAG10173.1 - 2.2e-30 105.2 0.1 4.8e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OAG10173.1 - 1.6e-26 92.3 2.4 2.3e-26 91.7 1.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Glycophorin_A PF01102.18 OAG10174.1 - 0.027 14.7 0.3 0.066 13.5 0.3 1.7 1 0 0 1 1 1 0 Glycophorin A Glutaredoxin PF00462.24 OAG10176.1 - 3e-12 46.6 0.1 8e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin SMBP PF16785.5 OAG10176.1 - 0.065 13.5 0.8 0.11 12.7 0.2 1.6 2 0 0 2 2 2 0 Small metal-binding protein PhyH PF05721.13 OAG10178.1 - 3.6e-14 53.5 0.0 4.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MCM PF00493.23 OAG10179.1 - 3.7e-103 343.5 0.3 5.7e-103 342.8 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG10179.1 - 2e-37 127.8 0.6 3.7e-37 127.0 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 OAG10179.1 - 3.2e-30 104.5 2.0 8e-30 103.3 2.0 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 OAG10179.1 - 8.3e-25 87.0 0.5 2.5e-24 85.5 0.2 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAG10179.1 - 1.2e-22 80.5 0.5 3.7e-22 78.9 0.1 2.2 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG10179.1 - 7.4e-08 32.0 0.0 8.4e-07 28.6 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAG10179.1 - 0.0012 18.8 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG10179.1 - 0.0015 18.2 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OAG10179.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Metallophos PF00149.28 OAG10180.1 - 3.7e-38 132.1 0.5 5.9e-38 131.4 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG10180.1 - 0.015 15.8 0.1 0.03 14.8 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain APC_u14 PF16635.5 OAG10181.1 - 0.024 15.2 0.7 0.065 13.8 0.7 1.7 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr PVL_ORF50 PF07768.11 OAG10181.1 - 0.15 12.4 2.1 0.32 11.3 0.9 2.1 2 0 0 2 2 2 0 PVL ORF-50-like family BrkDBD PF09607.10 OAG10182.1 - 0.093 12.5 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Brinker DNA-binding domain Basic PF01586.16 OAG10183.1 - 0.016 16.3 0.1 0.04 15.1 0.1 1.6 1 0 0 1 1 1 0 Myogenic Basic domain CLTH PF10607.9 OAG10185.1 - 1.4e-30 106.2 0.1 2.5e-30 105.3 0.1 1.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAG10185.1 - 1e-08 34.8 0.0 2.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 LisH MGS PF02142.22 OAG10185.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain PRK PF00485.18 OAG10186.1 - 3e-60 203.3 0.0 4.1e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 OAG10186.1 - 2.2e-40 138.3 0.0 3.2e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 OAG10186.1 - 1.3e-05 25.1 0.0 3.3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 OAG10186.1 - 0.00011 22.8 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAG10186.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 OAG10186.1 - 0.05 14.0 0.0 0.093 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 OAG10186.1 - 0.061 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 OAG10186.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OAG10186.1 - 0.12 12.8 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG10186.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 OAG10187.1 - 5.8e-36 124.9 0.3 7.8e-36 124.5 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG10187.1 - 0.026 15.0 0.4 0.065 13.7 0.4 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OAG10187.1 - 0.033 14.4 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain IF-2B PF01008.17 OAG10190.1 - 9e-53 179.3 0.0 1.1e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 OAG10190.1 - 0.064 13.2 0.0 0.86 9.5 0.0 2.3 1 1 0 1 1 1 0 DeoR C terminal sensor domain Aldedh PF00171.22 OAG10191.1 - 1.3e-153 511.9 0.1 1.6e-153 511.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG10191.1 - 1.3e-05 24.4 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 OAG10191.1 - 0.014 14.8 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Nbl1_Borealin_N PF10444.9 OAG10191.1 - 0.22 11.2 0.3 0.44 10.2 0.3 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal 2C_adapt PF08793.10 OAG10192.1 - 0.14 12.4 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 2-cysteine adaptor domain SUIM_assoc PF16619.5 OAG10192.1 - 0.26 11.4 3.3 2 8.5 0.2 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cyt-b5 PF00173.28 OAG10193.1 - 1.9e-14 53.6 0.0 3.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.20 OAG10193.1 - 7.8e-12 45.2 0.0 1.8e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain IDO PF01231.18 OAG10193.1 - 3.7e-11 42.5 0.0 5.3e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.21 OAG10193.1 - 6.3e-08 33.2 0.0 1.7e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain 2-Hacid_dh_C PF02826.19 OAG10194.1 - 2e-43 147.8 0.0 3.1e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG10194.1 - 7.6e-26 90.4 0.0 9e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 OAG10194.1 - 0.002 18.6 0.2 0.024 15.2 0.1 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent EthD PF07110.11 OAG10195.1 - 0.02 16.0 0.2 0.035 15.2 0.2 1.4 1 1 0 1 1 1 0 EthD domain DOT1 PF08123.13 OAG10195.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Peptidase_M28 PF04389.17 OAG10196.1 - 2.1e-39 135.3 0.0 3.1e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG10196.1 - 5.1e-13 48.8 4.6 5.1e-13 48.8 4.6 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 OAG10196.1 - 1.3e-05 25.0 0.1 3.2e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 LVIVD PF08309.11 OAG10197.1 - 0.0091 15.3 11.2 0.44 9.9 0.1 4.9 5 1 0 5 5 5 2 LVIVD repeat Beta_propel PF09826.9 OAG10197.1 - 0.079 11.8 0.1 2 7.1 0.1 2.2 1 1 0 2 2 2 0 Beta propeller domain HAD_2 PF13419.6 OAG10198.1 - 4.7e-24 85.4 0.0 7e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG10198.1 - 3.2e-10 40.7 0.0 1e-09 39.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAG10198.1 - 1.7e-05 25.3 0.0 2.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG10198.1 - 0.0003 20.8 0.0 0.00055 19.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAG10198.1 - 0.0035 17.4 0.0 0.035 14.2 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF4296 PF14129.6 OAG10198.1 - 0.066 13.8 0.1 6.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4296) DUF3854 PF12965.7 OAG10198.1 - 0.077 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) S_100 PF01023.19 OAG10198.1 - 0.43 10.3 2.8 0.44 10.3 0.1 2.5 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain LPMO_10 PF03067.15 OAG10199.1 - 0.0002 22.1 1.5 0.00065 20.4 1.5 1.7 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DAO PF01266.24 OAG10200.1 - 1.6e-40 139.8 0.9 1.9e-40 139.6 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG10200.1 - 0.0065 16.7 0.1 0.026 14.8 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG10200.1 - 0.052 12.8 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG10200.1 - 0.058 13.4 0.0 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG10200.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Ribonuclease_3 PF00636.26 OAG10201.1 - 1.5e-38 131.6 0.0 2.2e-19 70.0 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 OAG10201.1 - 4.1e-21 74.9 0.0 1.3e-20 73.3 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 OAG10201.1 - 5.3e-20 71.9 0.3 2.4e-09 37.4 0.0 4.1 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 OAG10201.1 - 1.6e-15 57.4 0.0 4.8e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG10201.1 - 7.7e-10 39.0 0.0 2.2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG10201.1 - 5.1e-08 32.9 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Microtub_bd PF16796.5 OAG10201.1 - 0.15 12.0 0.3 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Microtubule binding Flavi_DEAD PF07652.14 OAG10201.1 - 0.64 10.0 3.2 1.7 8.6 0.1 3.1 3 1 1 4 4 4 0 Flavivirus DEAD domain TAP42 PF04177.12 OAG10202.1 - 2.6e-107 358.7 4.9 2.9e-107 358.5 4.9 1.0 1 0 0 1 1 1 1 TAP42-like family Lipase_GDSL_2 PF13472.6 OAG10203.1 - 1.6e-12 48.2 0.0 3.6e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG10203.1 - 3.9e-10 40.0 0.0 8e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WD40 PF00400.32 OAG10205.1 - 5.2e-10 39.7 7.8 0.16 12.9 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.6 OAG10205.1 - 0.011 16.2 0.3 22 5.7 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain ANAPC4_WD40 PF12894.7 OAG10205.1 - 0.013 15.8 0.4 0.31 11.4 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 OAG10206.1 - 2.8e-12 46.1 3.7 5.6e-11 41.9 3.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10206.1 - 7.3e-08 32.4 9.8 1.3e-07 31.6 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YqhR PF11085.8 OAG10208.1 - 1.3 8.9 6.8 0.059 13.3 0.9 1.7 2 0 0 2 2 2 0 Conserved membrane protein YqhR She9_MDM33 PF05546.11 OAG10209.1 - 2.5e-57 193.9 8.5 3.6e-57 193.4 8.5 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DUF2564 PF10819.8 OAG10209.1 - 0.032 14.6 6.5 1.1 9.7 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Atg14 PF10186.9 OAG10209.1 - 0.063 12.4 5.2 0.051 12.7 2.6 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3813 PF12758.7 OAG10209.1 - 0.37 11.2 11.2 2 8.8 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) YscO-like PF16789.5 OAG10209.1 - 0.54 10.3 16.5 0.31 11.1 5.2 2.3 1 1 1 2 2 2 0 YscO-like protein I_LWEQ PF01608.17 OAG10209.1 - 5.9 7.1 15.9 0.31 11.3 8.7 2.4 2 1 1 3 3 3 0 I/LWEQ domain Exonuc_VII_L PF02601.15 OAG10209.1 - 6.6 6.2 13.4 2.2 7.8 9.1 2.2 2 1 0 2 2 2 0 Exonuclease VII, large subunit HAD PF12710.7 OAG10210.1 - 1.6e-24 87.4 0.0 2.1e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAG10210.1 - 0.00042 19.8 0.1 0.0042 16.5 0.1 2.0 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 OAG10210.1 - 0.036 13.6 0.0 0.17 11.4 0.0 2.0 2 1 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 OAG10210.1 - 0.047 14.0 0.8 3.1 8.0 0.0 2.9 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1681 PF07933.14 OAG10211.1 - 6.8e-57 191.3 0.0 9.8e-57 190.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) GILT PF03227.16 OAG10212.1 - 2.9e-19 69.3 0.1 4.6e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.21 OAG10213.1 - 8.3e-53 179.2 0.0 1.4e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 OAG10213.1 - 2.3e-51 174.6 0.0 3.1e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ADH_N PF08240.12 OAG10216.1 - 5.5e-31 106.7 0.5 8.7e-31 106.0 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG10216.1 - 2.3e-23 82.6 0.1 3.4e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG10216.1 - 1.2e-05 26.3 0.0 1.9e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG10216.1 - 0.016 14.6 0.1 0.029 13.8 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 OAG10216.1 - 0.12 11.8 0.0 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ABC_tran PF00005.27 OAG10218.1 - 3.4e-17 63.3 0.0 9.3e-09 35.9 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG10218.1 - 1.2e-07 31.9 0.1 0.0067 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAG10218.1 - 0.0021 18.3 0.1 0.017 15.3 0.1 2.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OAG10218.1 - 0.043 14.3 0.4 0.12 12.9 0.4 1.7 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 OAG10218.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 OAG10218.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3584 PF12128.8 OAG10218.1 - 0.18 9.3 0.2 0.28 8.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 OAG10218.1 - 0.29 9.7 0.0 0.42 9.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.21 OAG10219.1 - 9.3e-66 222.0 0.0 1.1e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.11 OAG10219.1 - 0.19 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like RNase_T PF00929.24 OAG10220.1 - 3.8e-18 66.6 0.0 5.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OAG10220.1 - 0.0011 18.7 0.0 0.0031 17.2 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease MOZ_SAS PF01853.18 OAG10221.1 - 4.6e-81 270.7 0.0 6.8e-81 270.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAG10221.1 - 7.2e-25 86.4 1.7 1.5e-24 85.4 1.7 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OAG10221.1 - 4.6e-23 80.9 0.2 1.1e-22 79.7 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OAG10221.1 - 0.0015 18.9 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG10221.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HCO3_cotransp PF00955.21 OAG10222.1 - 2.2e-69 234.6 10.5 2e-39 135.8 8.2 2.2 1 1 1 2 2 2 2 HCO3- transporter family SET PF00856.28 OAG10223.1 - 5.3e-09 36.7 0.0 1.5e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-C2H2 PF00096.26 OAG10224.1 - 9.4e-12 44.7 66.2 0.032 14.7 0.1 11.2 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG10224.1 - 1.9e-09 37.5 61.4 0.065 14.1 0.4 10.6 10 1 1 11 11 11 6 C2H2-type zinc finger zf-met PF12874.7 OAG10224.1 - 3.2e-06 27.4 50.8 0.011 16.0 0.2 10.2 10 1 1 11 11 11 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG10224.1 - 0.043 14.1 0.3 0.043 14.1 0.3 9.4 11 0 0 11 11 11 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OAG10224.1 - 0.051 13.9 1.0 0.051 13.9 1.0 5.2 2 1 4 6 6 6 0 C2H2-type zinc ribbon Rad60-SLD PF11976.8 OAG10226.1 - 8.4e-15 54.4 0.1 1.2e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAG10226.1 - 1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family MTCP1 PF08991.10 OAG10227.1 - 3.6e-25 87.9 12.2 4.2e-25 87.7 12.2 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type DUF4051 PF13260.6 OAG10227.1 - 0.0044 16.7 0.4 0.0044 16.7 0.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4051) CHCH PF06747.13 OAG10227.1 - 0.47 10.6 11.6 0.095 12.9 7.9 1.9 2 0 0 2 2 2 0 CHCH domain PIP49_C PF12260.8 OAG10227.1 - 0.49 10.0 7.9 0.47 10.1 7.9 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Nup84_Nup100 PF04121.13 OAG10228.1 - 3.3e-108 362.7 0.0 1.1e-96 324.6 0.0 2.1 1 1 1 2 2 2 2 Nuclear pore protein 84 / 107 TFR_dimer PF04253.15 OAG10228.1 - 0.095 12.8 1.9 6 7.0 0.2 3.0 3 0 0 3 3 3 0 Transferrin receptor-like dimerisation domain Phage_min_cap2 PF06152.11 OAG10228.1 - 0.13 11.1 2.5 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Phage minor capsid protein 2 Peptidase_C48 PF02902.19 OAG10229.1 - 7.7e-18 65.1 0.0 1.7e-17 64.0 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 OAG10229.1 - 0.019 13.7 0.0 0.093 11.4 0.0 1.8 1 1 0 1 1 1 0 Vaccinia virus I7 processing peptidase ADH_zinc_N PF00107.26 OAG10230.1 - 2.1e-28 98.9 0.1 3.3e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG10230.1 - 5.3e-13 50.2 0.0 1.1e-12 49.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG10230.1 - 1.2e-11 44.5 0.0 4e-11 42.8 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 OAG10230.1 - 7.4e-05 23.0 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OAG10230.1 - 0.061 12.6 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ni_hydr_CYTB PF01292.20 OAG10231.1 - 0.011 15.3 2.4 0.011 15.3 2.4 1.7 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 PAT1 PF09770.9 OAG10232.1 - 0 1158.9 6.7 0 1158.7 6.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 OAG10233.1 - 1.5e-129 431.9 8.2 1.8e-129 431.6 8.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 OAG10233.1 - 0.24 11.6 2.4 0.45 10.7 2.4 1.4 1 0 0 1 1 1 0 EGF domain Acyltransferase PF01553.21 OAG10234.1 - 4.8e-17 61.8 0.0 9.1e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Asp PF00026.23 OAG10235.1 - 5.8e-65 219.8 8.6 7.5e-65 219.4 8.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 OAG10235.1 - 1.9e-07 31.6 3.3 0.00077 20.1 1.8 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.6 OAG10235.1 - 2.2e-07 31.3 4.1 0.00049 20.4 1.3 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 OAG10235.1 - 0.003 18.1 2.8 0.82 10.3 1.0 3.0 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAG10235.1 - 0.017 14.9 0.2 0.071 12.9 0.0 2.1 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal TPR_2 PF07719.17 OAG10237.1 - 1.5e-08 34.1 22.7 0.0011 18.9 0.0 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG10237.1 - 1.8e-05 24.4 3.7 0.086 12.7 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG10237.1 - 5.3e-05 23.3 4.5 0.33 11.4 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG10237.1 - 0.0001 22.7 16.9 0.0082 16.6 0.2 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG10237.1 - 0.00019 21.6 0.9 0.00019 21.6 0.9 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG10237.1 - 0.00033 20.3 4.3 1.6 8.5 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 OAG10237.1 - 0.0004 20.4 7.2 9.4 6.7 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat SBP_bac_11 PF13531.6 OAG10237.1 - 0.073 12.8 0.5 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein TPR_4 PF07721.14 OAG10237.1 - 0.15 12.8 6.4 5.4 7.9 0.6 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat HemY_N PF07219.13 OAG10237.1 - 0.18 12.0 0.9 6.6 7.0 0.0 3.0 2 1 1 3 3 3 0 HemY protein N-terminus TPR_16 PF13432.6 OAG10237.1 - 0.28 11.9 24.2 5.4 7.8 0.3 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG10237.1 - 4 7.4 6.7 19 5.3 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Oxysterol_BP PF01237.18 OAG10239.1 - 1.2e-54 185.6 0.0 1.5e-46 158.9 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein OB_RNB PF08206.11 OAG10239.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain Asparaginase PF00710.20 OAG10240.1 - 1.2e-51 175.0 1.8 1.7e-51 174.5 1.8 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG10240.1 - 1e-20 74.0 0.0 3.3e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain TPP_enzyme_M PF00205.22 OAG10240.1 - 0.00084 19.1 0.1 0.0084 15.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_11 PF00457.17 OAG10241.1 - 2.6e-80 268.2 20.5 3e-80 268.0 20.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Snf7 PF03357.21 OAG10242.1 - 5e-17 62.0 17.3 7.6e-17 61.4 17.3 1.3 1 0 0 1 1 1 1 Snf7 ESSS PF10183.9 OAG10242.1 - 1.6e-14 53.9 0.0 3.4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.6 OAG10242.1 - 1.8 8.3 4.7 3.6 7.3 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) ATP_bind_1 PF03029.17 OAG10243.1 - 2.9e-76 256.4 0.0 5.6e-76 255.5 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 OAG10243.1 - 0.00013 21.1 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 OAG10243.1 - 0.00016 21.6 0.0 0.22 11.4 0.0 2.4 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG10243.1 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Fer4_NifH PF00142.18 OAG10243.1 - 0.0061 16.0 0.2 0.04 13.4 0.2 2.1 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_18 PF13238.6 OAG10243.1 - 0.0089 16.6 0.1 0.23 12.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAG10243.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain KTI12 PF08433.10 OAG10243.1 - 0.015 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 OAG10243.1 - 0.021 15.2 0.0 0.13 12.6 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 OAG10243.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 OAG10243.1 - 0.044 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.22 OAG10243.1 - 0.085 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CLP1_P PF16575.5 OAG10243.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 OAG10243.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAG10243.1 - 0.14 12.2 0.0 1.2 9.3 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG10243.1 - 0.16 12.3 0.0 0.33 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OAG10243.1 - 0.17 12.3 1.4 0.26 11.7 0.1 2.0 2 0 0 2 2 1 0 AAA domain WD40 PF00400.32 OAG10244.1 - 2.5e-14 53.4 3.5 0.02 15.7 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG10244.1 - 0.0049 17.1 0.0 4.6 7.6 0.0 4.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain IML1 PF12257.8 OAG10245.1 - 2.7e-118 394.2 0.0 3.9e-118 393.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 OAG10245.1 - 1e-26 92.8 0.1 2.4e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.6 OAG10246.1 - 3.8e-28 99.4 0.2 3.8e-28 99.4 0.2 3.5 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus Nucleoporin_FG PF13634.6 OAG10247.1 - 1.7e-24 86.4 134.9 1.9e-11 44.7 30.5 3.5 2 1 3 5 5 5 4 Nucleoporin FG repeat region DUF1515 PF07439.11 OAG10247.1 - 0.0028 17.7 0.4 0.0075 16.3 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) Syntaxin-6_N PF09177.11 OAG10247.1 - 0.0067 17.0 3.2 0.0094 16.5 0.2 2.5 2 1 0 3 3 3 1 Syntaxin 6, N-terminal Not3 PF04065.15 OAG10247.1 - 0.0082 15.6 0.6 0.19 11.1 0.1 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component CENP-F_leu_zip PF10473.9 OAG10247.1 - 0.023 14.7 0.8 0.3 11.1 0.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MIP-T3_C PF17749.1 OAG10247.1 - 0.032 14.2 0.1 0.032 14.2 0.1 2.7 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF948 PF06103.11 OAG10247.1 - 0.045 14.0 1.1 2.9 8.2 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Herpes_BBRF1 PF04793.12 OAG10247.1 - 0.055 12.5 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 BRRF1-like protein DUF4201 PF13870.6 OAG10247.1 - 0.099 12.4 3.2 0.99 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Fip1 PF05182.13 OAG10248.1 - 1.9e-18 65.7 2.2 3.9e-18 64.7 2.2 1.5 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.12 OAG10248.1 - 0.047 12.3 3.4 0.056 12.0 3.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 OAG10248.1 - 3.9 5.7 4.4 3.8 5.7 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAG10248.1 - 5.4 5.1 11.0 6.8 4.8 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 OAG10248.1 - 8.1 6.3 8.5 14 5.5 8.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region GST_N_2 PF13409.6 OAG10249.1 - 6.3e-20 71.3 0.0 1.5e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG10249.1 - 3.6e-13 49.3 0.0 8e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG10249.1 - 2.8e-05 24.4 0.0 0.00095 19.5 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG10249.1 - 0.00073 19.7 0.0 0.0023 18.1 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CLN5 PF15014.6 OAG10249.1 - 0.035 13.8 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Ceroid-lipofuscinosis neuronal protein 5 RNA_pol PF00940.19 OAG10250.1 - 4.9e-183 608.7 0.0 7.5e-183 608.1 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OAG10250.1 - 1.7e-82 277.6 8.3 3.1e-82 276.7 8.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Centro_C10orf90 PF17730.1 OAG10250.1 - 0.023 13.5 0.4 0.04 12.7 0.4 1.3 1 0 0 1 1 1 0 Centrosomal C10orf90 PBP1_TM PF14812.6 OAG10251.1 - 0.54 10.7 2.3 52 4.3 1.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal p450 PF00067.22 OAG10252.1 - 2.8e-65 220.9 0.0 3.2e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rhabdo_M1 PF03342.13 OAG10253.1 - 0.026 13.9 2.1 0.17 11.2 0.0 2.3 2 1 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) DEAD_assoc PF08494.11 OAG10255.1 - 0.07 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 DEAD/H associated Glycos_transf_1 PF00534.20 OAG10256.1 - 3.7e-34 117.7 0.0 1.8e-33 115.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG10256.1 - 3.3e-17 63.0 0.2 6.4e-17 62.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAG10256.1 - 3.6e-15 56.6 0.1 1e-14 55.1 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG10256.1 - 6.9e-09 36.3 0.5 6.9e-09 36.3 0.5 2.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 OAG10256.1 - 0.00071 19.7 0.4 1 9.3 0.2 2.9 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_1_2 PF13524.6 OAG10256.1 - 0.0017 18.7 0.0 0.0045 17.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 LysR_substrate PF03466.20 OAG10256.1 - 0.015 14.7 0.1 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 LysR substrate binding domain Pkinase PF00069.25 OAG10257.1 - 2.2e-23 83.0 0.0 3.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 OAG10257.1 - 6e-15 54.1 5.8 0.0095 16.1 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat WD40 PF00400.32 OAG10257.1 - 6e-12 45.9 4.5 1.2e-05 25.9 0.1 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 OAG10257.1 - 8.7e-10 38.9 0.1 0.0029 18.0 0.0 4.2 2 2 1 3 3 3 3 HEAT repeats Pkinase_Tyr PF07714.17 OAG10257.1 - 7e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG10257.1 - 0.00032 20.1 0.0 0.00063 19.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Cnd1 PF12717.7 OAG10257.1 - 0.00039 20.5 0.1 1.8 8.5 0.0 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG10257.1 - 1 10.0 6.3 16 6.1 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat Bac_rhodopsin PF01036.18 OAG10259.1 - 3.2e-57 193.7 10.4 4.3e-57 193.3 10.4 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SQS_PSY PF00494.19 OAG10260.1 - 6.8e-63 212.6 2.7 8.5e-63 212.3 2.7 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.15 OAG10261.1 - 1.3e-116 390.5 0.0 1.6e-116 390.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Gly_transf_sug PF04488.15 OAG10262.1 - 0.011 16.3 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif Myb_DNA-binding PF00249.31 OAG10263.1 - 8.5e-13 48.3 0.1 5.3e-07 29.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG10263.1 - 6.5e-09 35.9 0.0 0.0039 17.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OAG10263.1 - 0.0015 18.5 0.1 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 SLIDE SANT_DAMP1_like PF16282.5 OAG10263.1 - 0.021 15.0 0.1 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 4HBT PF03061.22 OAG10264.1 - 2.3e-08 34.2 0.0 3.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 OAG10264.1 - 0.00017 20.9 0.1 0.00027 20.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OAG10264.1 - 0.00085 19.8 0.0 0.0011 19.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_transf_90 PF05686.12 OAG10265.1 - 9.4e-22 77.5 0.5 1.3e-21 77.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 zf-rbx1 PF12678.7 OAG10266.1 - 4.2e-10 39.8 3.4 1.4e-09 38.1 0.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG10266.1 - 1.2e-09 38.4 5.7 2.6e-07 30.9 0.8 2.7 3 0 0 3 3 2 2 Ring finger domain zf-ANAPC11 PF12861.7 OAG10266.1 - 1.3e-06 28.4 0.4 5.3e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAG10266.1 - 3.6e-06 26.7 4.7 1.4e-05 24.9 0.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG10266.1 - 3.9e-05 23.4 8.2 0.00013 21.7 1.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG10266.1 - 8.4e-05 22.1 0.5 8.4e-05 22.1 0.5 2.2 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OAG10266.1 - 0.00021 21.2 1.8 0.0035 17.3 0.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAG10266.1 - 0.00059 19.5 5.7 0.038 13.7 0.3 3.4 3 0 0 3 3 3 1 RING-like zinc finger RINGv PF12906.7 OAG10266.1 - 0.00065 19.8 2.7 0.001 19.1 0.6 2.2 2 0 0 2 2 2 1 RING-variant domain Prok-RING_4 PF14447.6 OAG10266.1 - 0.00081 19.2 9.5 0.0052 16.6 3.2 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG10266.1 - 0.0021 17.9 9.0 0.0043 16.9 2.3 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG10266.1 - 0.0054 16.7 9.6 0.037 14.1 1.1 3.3 2 1 1 3 3 3 1 RING-type zinc-finger BST2 PF16716.5 OAG10266.1 - 0.047 14.3 0.2 0.095 13.3 0.2 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 zf-RING_4 PF14570.6 OAG10266.1 - 0.18 11.6 3.2 1.1 9.2 0.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OAG10266.1 - 0.22 11.7 5.7 1.2 9.3 3.3 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain CTU2 PF10288.9 OAG10266.1 - 0.27 11.5 1.4 2.9 8.1 1.5 2.2 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_4 PF15227.6 OAG10266.1 - 0.4 10.9 4.0 1.4 9.1 0.9 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OAG10266.1 - 1.9 8.3 6.0 1.6 8.6 1.9 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 OAG10266.1 - 2.1 8.8 8.3 0.11 12.9 2.3 2.0 2 0 0 2 2 2 0 RING-like domain Rad50_zn_hook PF04423.14 OAG10266.1 - 2.1 8.3 6.1 8.7 6.3 0.1 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif Zf_RING PF16744.5 OAG10266.1 - 8.6 6.6 8.8 0.6 10.3 2.6 2.3 3 1 1 4 4 2 0 KIAA1045 RING finger HIG_1_N PF04588.13 OAG10267.1 - 7.6e-19 67.7 0.1 1e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2681 PF10883.8 OAG10267.1 - 0.039 14.3 1.3 0.059 13.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CCDC-167 PF15188.6 OAG10267.1 - 1.2 9.6 7.6 6.2 7.2 7.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1746 PF08508.10 OAG10268.1 - 2.5e-35 121.3 0.1 3.4e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) FAM176 PF14851.6 OAG10268.1 - 7.9 6.1 6.7 0.63 9.7 0.7 1.9 2 0 0 2 2 2 0 FAM176 family bZIP_2 PF07716.15 OAG10271.1 - 0.0071 16.4 10.5 0.012 15.6 10.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Sugar_tr PF00083.24 OAG10275.1 - 1.9e-78 264.3 28.7 2.4e-78 264.1 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10275.1 - 9.4e-21 74.1 42.6 3.6e-16 59.0 35.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M28 PF04389.17 OAG10276.1 - 5.9e-33 114.2 0.0 8.5e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG10276.1 - 1.4e-14 53.9 0.2 2.6e-14 53.0 0.2 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG10276.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HET PF06985.11 OAG10277.1 - 2.4e-34 118.8 0.0 2.7e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Neuralized PF07177.12 OAG10277.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Neuralized ABC1 PF03109.16 OAG10278.1 - 2.7e-22 79.2 0.0 5.7e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Yae1_N PF09811.9 OAG10278.1 - 1.1e-10 41.1 2.1 3e-10 39.6 2.1 1.8 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ATP_transf PF09830.9 OAG10279.1 - 4.6e-19 68.3 0.0 8.4e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 OAG10279.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) HIT PF01230.23 OAG10279.1 - 0.076 13.8 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 HIT domain DSBA PF01323.20 OAG10281.1 - 1.3e-22 80.5 0.0 1.5e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.25 OAG10282.1 - 8.1e-31 107.0 1.7 3e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10282.1 - 9e-24 84.3 0.4 1.5e-19 70.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10282.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG10282.1 - 3.2e-05 23.4 0.0 0.00016 21.2 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 OAG10282.1 - 0.018 14.4 0.3 0.033 13.5 0.3 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peripla_BP_6 PF13458.6 OAG10282.1 - 0.059 13.0 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Epimerase PF01370.21 OAG10282.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PspC PF04024.12 OAG10285.1 - 0.12 12.2 6.8 21 5.0 0.0 6.0 6 1 0 6 6 6 0 PspC domain Glyco_hydro_18 PF00704.28 OAG10289.1 - 3.7e-84 283.1 7.8 4.4e-84 282.9 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BRX_assoc PF16627.5 OAG10290.1 - 0.14 12.3 0.6 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain Sod_Fe_N PF00081.22 OAG10291.1 - 1.1e-34 118.7 2.9 1.1e-34 118.7 2.9 1.8 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 OAG10291.1 - 1.7e-33 114.8 0.2 2.8e-33 114.1 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sugar_tr PF00083.24 OAG10293.1 - 2.1e-121 405.9 22.6 6.2e-121 404.4 22.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10293.1 - 5.5e-25 88.0 36.0 1.3e-18 67.1 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tom6 PF17112.5 OAG10293.1 - 2.9 7.5 6.4 0.3 10.6 0.2 2.6 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom6, fungal DUF5325 PF17259.2 OAG10293.1 - 8.5 6.3 10.1 0.9 9.5 2.8 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Peptidase_M28 PF04389.17 OAG10294.1 - 4e-34 118.1 0.0 1.2e-33 116.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 zf-3CxxC PF13695.6 OAG10295.1 - 0.072 13.6 0.1 0.29 11.6 0.1 2.1 1 0 0 1 1 1 0 Zinc-binding domain FancD2 PF14631.6 OAG10295.1 - 1 6.7 5.7 1.5 6.1 5.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease 7tm_3 PF00003.22 OAG10296.1 - 0.02 14.6 0.5 0.034 13.9 0.5 1.3 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Tetraspanin PF00335.20 OAG10296.1 - 0.038 13.7 1.8 0.23 11.1 0.6 2.5 3 0 0 3 3 3 0 Tetraspanin family DUF202 PF02656.15 OAG10296.1 - 0.067 13.6 8.1 0.14 12.6 1.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) SUR7 PF06687.12 OAG10296.1 - 0.63 9.6 5.4 0.12 12.0 0.5 2.0 1 1 1 2 2 2 0 SUR7/PalI family PMP22_Claudin PF00822.20 OAG10296.1 - 1.1 9.1 4.9 0.4 10.5 2.0 1.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family CopD PF05425.13 OAG10296.1 - 1.6 9.2 6.1 0.82 10.1 0.7 2.6 3 0 0 3 3 3 0 Copper resistance protein D NTF2 PF02136.20 OAG10297.1 - 9.2e-25 87.5 0.7 1.6e-24 86.8 0.7 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OAG10297.1 - 1e-08 34.8 0.1 2e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAG10297.1 - 0.029 14.4 0.1 0.077 13.1 0.1 1.7 1 0 0 1 1 1 0 RNA binding motif FAM196 PF15265.6 OAG10297.1 - 1.9 7.9 11.5 2.9 7.3 11.5 1.3 1 0 0 1 1 1 0 FAM196 family Septin PF00735.18 OAG10298.1 - 3e-16 59.5 0.0 3e-15 56.3 0.0 2.1 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 OAG10298.1 - 0.0019 18.6 0.0 0.0094 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAG10298.1 - 0.0068 16.5 0.0 0.033 14.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 OAG10298.1 - 0.013 15.4 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 OAG10298.1 - 0.11 12.9 0.2 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAG10298.1 - 0.12 11.7 0.1 0.31 10.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 OAG10298.1 - 0.13 12.2 0.1 0.53 10.2 0.1 2.0 3 0 0 3 3 3 0 RsgA GTPase AAA_24 PF13479.6 OAG10298.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG10298.1 - 0.19 12.0 0.2 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain COesterase PF00135.28 OAG10300.1 - 4.3e-89 299.7 0.0 5.4e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG10300.1 - 0.0045 16.9 0.1 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_61 PF03443.14 OAG10301.1 - 2.6e-50 171.2 0.3 4.1e-50 170.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 OAG10301.1 - 1.1e-13 50.9 12.1 2.8e-13 49.6 12.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain WSC PF01822.19 OAG10306.1 - 7.4e-51 170.3 39.3 7.1e-18 64.6 6.9 3.7 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.11 OAG10306.1 - 5.6e-29 101.0 0.0 3.2e-27 95.3 0.0 2.8 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 OAG10306.1 - 3.4e-21 75.3 0.1 8.8e-21 74.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyco_hydro_16 PF00722.21 OAG10307.1 - 3e-17 62.6 0.1 9.8e-17 61.0 0.1 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 OAG10308.1 - 1.5e-50 171.9 3.2 7.3e-50 169.6 3.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG10308.1 - 0.0091 15.8 0.0 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 RHH_1 PF01402.21 OAG10308.1 - 0.12 12.4 0.3 0.4 10.7 0.3 1.9 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family PIN_4 PF13638.6 OAG10309.1 - 0.0029 17.9 0.2 0.051 13.9 0.0 2.4 3 0 0 3 3 3 1 PIN domain Translin PF01997.16 OAG10310.1 - 9.5e-66 221.7 0.0 1.1e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Translin family Sigma70_ner PF04546.13 OAG10310.1 - 0.066 13.1 0.3 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Mannosyl_trans PF05007.13 OAG10311.1 - 1.7e-77 260.8 10.4 2.6e-77 260.2 10.4 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 OAG10311.1 - 3.2e-13 49.5 3.6 3.2e-13 49.5 3.6 1.8 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U HPD PF05044.12 OAG10311.1 - 0.056 13.3 0.5 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 Homeo-prospero domain GT87 PF09594.10 OAG10311.1 - 0.14 11.9 22.4 0.023 14.4 16.8 2.5 1 1 1 2 2 2 0 Glycosyltransferase family 87 HET PF06985.11 OAG10312.1 - 2.5e-24 86.3 0.0 4.7e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mur_ligase_M PF08245.12 OAG10313.1 - 1e-06 28.9 0.3 0.0017 18.4 0.0 3.4 1 1 1 2 2 2 2 Mur ligase middle domain DUF2322 PF10084.9 OAG10313.1 - 0.015 15.3 0.2 1.4 9.0 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) Mur_ligase_C PF02875.21 OAG10313.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ANAPC4_WD40 PF12894.7 OAG10315.1 - 5.2e-06 26.7 0.0 0.003 17.8 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OAG10315.1 - 0.012 15.2 0.5 0.036 13.7 0.0 2.0 2 1 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 OAG10315.1 - 0.016 16.0 1.9 12 7.0 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 OAG10315.1 - 0.11 11.7 0.0 8.5 5.5 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIF_alpha PF05793.12 OAG10315.1 - 0.33 9.5 14.4 0.46 9.0 14.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PQQ_3 PF13570.6 OAG10315.1 - 0.87 10.2 4.1 12 6.5 0.1 3.4 4 0 0 4 4 4 0 PQQ-like domain RNA_polI_A34 PF08208.11 OAG10315.1 - 0.93 9.5 8.5 1.8 8.6 8.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 OAG10315.1 - 1.2 7.3 8.9 1.7 6.9 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.8 OAG10315.1 - 1.4 8.7 8.9 2.2 8.1 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nop14 PF04147.12 OAG10315.1 - 1.5 6.9 9.2 2 6.5 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_61 PF03443.14 OAG10316.1 - 1.2e-58 198.5 0.0 1.4e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF2838 PF10998.8 OAG10317.1 - 1e-44 151.3 8.7 1e-44 151.3 8.7 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.18 OAG10317.1 - 0.00026 20.9 8.2 0.00033 20.6 6.6 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 OAG10317.1 - 0.033 13.7 3.9 0.033 13.8 2.7 1.5 2 0 0 2 2 2 0 fzo-like conserved region Exonuc_VII_L PF02601.15 OAG10317.1 - 0.091 12.3 5.8 0.15 11.6 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 OAG10317.1 - 0.14 11.5 1.2 0.24 10.7 1.2 1.3 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 OAG10317.1 - 1.2 9.4 5.4 17 5.6 3.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 OAG10317.1 - 2.7 8.6 3.8 3.8 8.1 2.1 2.0 2 0 0 2 2 2 0 YtxH-like protein ApoLp-III PF07464.11 OAG10317.1 - 4.2 7.5 5.7 3.9 7.6 3.0 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Tropomyosin_1 PF12718.7 OAG10317.1 - 4.5 7.4 11.5 0.39 10.9 7.1 1.4 2 0 0 2 2 2 0 Tropomyosin like SMC_N PF02463.19 OAG10318.1 - 7.4e-50 169.4 29.2 3.5e-49 167.2 29.2 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAG10318.1 - 7e-26 90.8 0.0 2.7e-25 89.0 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAG10318.1 - 9.2e-11 42.1 18.9 6.1e-06 26.3 0.6 4.7 4 3 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG10318.1 - 2.1e-09 37.0 0.0 4.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 OAG10318.1 - 1.9e-05 25.0 10.2 1.9e-05 25.0 10.2 8.0 4 2 3 7 7 7 1 Autophagy protein 16 (ATG16) BRE1 PF08647.11 OAG10318.1 - 0.00092 19.2 14.4 0.00092 19.2 14.4 8.8 5 4 3 8 8 7 2 BRE1 E3 ubiquitin ligase DHR10 PF18595.1 OAG10318.1 - 0.004 17.2 13.9 0.004 17.2 13.9 9.6 5 4 2 8 8 7 2 Designed helical repeat protein 10 domain Spc7 PF08317.11 OAG10318.1 - 0.018 14.0 133.9 0.044 12.7 22.7 8.0 3 2 5 8 8 8 0 Spc7 kinetochore protein SbcCD_C PF13558.6 OAG10318.1 - 0.021 15.0 0.0 0.069 13.4 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 OAG10318.1 - 0.022 14.8 65.5 0.046 13.8 1.7 8.1 5 4 3 8 8 8 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 OAG10318.1 - 0.19 10.3 101.8 0.5 8.9 1.9 5.7 3 2 0 4 4 4 0 AAA domain DUF2939 PF11159.8 OAG10318.1 - 0.24 11.8 2.3 27 5.3 0.3 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Mating_N PF12731.7 OAG10318.1 - 2.9 8.1 7.8 19 5.4 0.4 4.4 5 0 0 5 5 5 0 Mating-type protein beta 1 GAS PF13851.6 OAG10318.1 - 2.9 7.2 124.2 0.085 12.2 18.3 6.6 5 1 0 6 6 6 0 Growth-arrest specific micro-tubule binding DUF1474 PF07342.11 OAG10318.1 - 7.8 7.1 9.3 2.2 8.9 1.0 4.1 4 0 0 4 4 3 0 Protein of unknown function (DUF1474) S-antigen PF05756.11 OAG10318.1 - 8.8 6.8 8.2 0.88 10.0 0.5 3.4 2 0 0 2 2 2 0 S-antigen protein p450 PF00067.22 OAG10320.1 - 1.8e-51 175.3 0.0 2.4e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG10320.1 - 1.9e-16 60.0 34.8 1.4e-09 37.4 12.9 3.4 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 OAG10320.1 - 0.00055 18.7 0.0 0.0016 17.1 0.0 1.8 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like PetL PF05115.14 OAG10320.1 - 0.018 15.0 0.2 0.082 12.9 0.2 2.2 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) MFS_1_like PF12832.7 OAG10320.1 - 0.019 13.8 0.1 5 5.9 0.0 2.3 2 0 0 2 2 2 0 MFS_1 like family HalX PF08663.10 OAG10321.1 - 0.0019 18.5 13.7 0.08 13.3 8.5 2.7 2 0 0 2 2 2 2 HalX domain Tropomyosin_1 PF12718.7 OAG10321.1 - 0.0052 16.9 10.6 0.0052 16.9 10.6 3.1 2 1 1 3 3 3 1 Tropomyosin like Imm7 PF15585.6 OAG10321.1 - 0.092 13.0 0.8 0.3 11.4 0.6 1.9 1 1 0 1 1 1 0 Immunity protein 7 Spectrin PF00435.21 OAG10321.1 - 0.18 12.3 20.3 0.87 10.1 5.4 3.4 2 1 1 3 3 3 0 Spectrin repeat FlaC_arch PF05377.11 OAG10321.1 - 0.24 11.8 11.7 0.2 12.1 1.6 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 OAG10321.1 - 0.47 10.6 12.3 7.1 6.8 1.6 3.9 3 1 0 3 3 3 0 bZIP transcription factor Spc7 PF08317.11 OAG10321.1 - 0.56 9.0 24.6 0.094 11.6 16.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-Q PF13094.6 OAG10321.1 - 0.85 9.8 26.4 1.5 9.0 3.7 3.4 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.9 OAG10321.1 - 0.85 9.6 27.1 4.4 7.3 15.4 3.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3138 PF11336.8 OAG10321.1 - 0.91 8.1 2.9 12 4.4 1.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) Cnn_1N PF07989.11 OAG10321.1 - 1.3 9.2 20.9 0.52 10.5 0.3 4.0 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 OAG10321.1 - 1.4 9.0 20.6 29 4.7 1.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 OAG10321.1 - 1.4 9.0 28.2 0.8 9.8 14.6 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cep57_MT_bd PF06657.13 OAG10321.1 - 1.8 9.0 19.8 3.5 8.1 3.2 4.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 OAG10321.1 - 1.8 8.7 26.1 1.2 9.3 15.0 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 OAG10321.1 - 2.3 7.5 13.1 8.8 5.6 13.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ERM PF00769.19 OAG10321.1 - 2.3 8.0 26.1 0.22 11.3 16.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CP12 PF02672.15 OAG10321.1 - 2.9 8.7 9.5 0.69 10.7 1.0 3.2 3 0 0 3 3 2 0 CP12 domain GAS PF13851.6 OAG10321.1 - 3.8 6.8 25.5 9.9 5.5 0.7 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 OAG10321.1 - 4.4 7.7 22.5 1.1 9.6 16.1 2.5 3 0 0 3 3 3 0 Fez1 Rootletin PF15035.6 OAG10321.1 - 6.1 6.8 19.9 7.6 6.5 12.3 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cep57_CLD_2 PF14197.6 OAG10321.1 - 8.2 6.6 24.9 0.15 12.2 4.3 5.0 4 1 2 6 6 6 0 Centrosome localisation domain of PPC89 Sec34 PF04136.15 OAG10321.1 - 9.9 6.0 14.3 4.1 7.3 5.3 2.7 2 1 0 2 2 2 0 Sec34-like family Glucosamine_iso PF01182.20 OAG10323.1 - 2.6e-67 227.0 0.0 3.2e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase zinc_ribbon_10 PF10058.9 OAG10324.1 - 0.018 14.8 1.5 0.028 14.1 1.5 1.3 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Retinal PF15449.6 OAG10324.1 - 0.44 8.3 8.5 0.48 8.2 8.5 1.0 1 0 0 1 1 1 0 Retinal protein SSrecog PF03531.14 OAG10326.1 - 6.9e-30 102.8 0.2 5.4e-29 99.9 0.0 2.6 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 OAG10326.1 - 5.8e-27 93.9 0.0 4.8e-26 91.0 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 OAG10326.1 - 3.3e-26 91.5 0.5 5.8e-25 87.6 0.2 2.6 2 0 0 2 2 2 1 POB3-like N-terminal PH domain CDC45 PF02724.14 OAG10326.1 - 3.8 5.7 9.5 6.9 4.8 9.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans_2 PF11951.8 OAG10327.1 - 2e-13 49.9 0.1 5.7e-13 48.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10327.1 - 3.7e-06 27.0 14.8 7.2e-06 26.0 14.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAS_I_H PF18314.1 OAG10327.1 - 0.12 11.9 0.2 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain XPA_C PF05181.12 OAG10329.1 - 0.011 15.7 0.2 0.02 14.9 0.2 1.4 1 0 0 1 1 1 0 XPA protein C-terminus CDC27 PF09507.10 OAG10329.1 - 0.16 11.3 35.4 0.28 10.5 35.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.11 OAG10329.1 - 1.2 7.6 31.4 1.7 7.1 31.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF966 PF06136.13 OAG10329.1 - 1.4 8.6 20.8 1.9 8.1 20.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hamartin PF04388.12 OAG10329.1 - 1.7 7.2 15.8 1.9 7.0 15.8 1.1 1 0 0 1 1 1 0 Hamartin protein Mitofilin PF09731.9 OAG10329.1 - 2.5 6.8 32.0 3 6.6 32.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Arylesterase PF01731.20 OAG10330.1 - 0.0047 17.1 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Arylesterase Metallophos PF00149.28 OAG10333.1 - 2.4e-40 139.2 0.1 3.1e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG10333.1 - 5.8e-23 81.1 1.8 8.5e-23 80.5 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain LRR_4 PF12799.7 OAG10334.1 - 1.7e-11 44.2 9.4 0.0001 22.6 1.6 4.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG10334.1 - 1.3e-08 34.5 14.5 1.8e-06 27.6 2.0 3.7 2 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OAG10334.1 - 0.00086 19.2 10.0 7.4 6.9 0.1 5.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 OAG10334.1 - 0.0011 18.6 0.9 0.0054 16.2 0.5 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OAG10334.1 - 0.0016 18.7 6.5 36 5.4 0.5 6.0 5 0 0 5 5 5 0 Leucine Rich Repeat Dicty_CAR PF05462.11 OAG10336.1 - 2.4e-11 43.3 8.3 2.4e-11 43.3 8.3 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 OAG10336.1 - 2.1e-09 37.5 12.2 2.7e-09 37.1 10.3 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 OAG10336.1 - 0.0028 16.7 11.9 0.2 10.6 11.9 2.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Peptidase_M56 PF05569.11 OAG10336.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 7TM_GPCR_Srsx PF10320.9 OAG10336.1 - 0.019 14.4 1.8 0.03 13.7 1.8 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4551 PF15087.6 OAG10336.1 - 0.15 10.9 0.2 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GPR_Gpa2_C PF11970.8 OAG10336.1 - 0.29 11.2 4.4 0.11 12.6 0.6 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Catalase PF00199.19 OAG10337.1 - 2.8e-18 66.2 0.0 4.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Catalase Pkinase PF00069.25 OAG10338.1 - 1.3e-74 250.9 0.0 1.5e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG10338.1 - 2.9e-36 125.1 0.0 3.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG10338.1 - 0.0033 16.4 0.0 0.025 13.5 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG10338.1 - 0.11 12.4 1.9 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF945 PF06097.11 OAG10338.1 - 0.78 8.8 4.0 1.2 8.2 4.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) WD40 PF00400.32 OAG10339.1 - 1.8e-19 69.7 9.9 4.6e-06 27.3 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG10339.1 - 0.00035 20.8 0.0 0.0025 18.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain GLTSCR1 PF15249.6 OAG10339.1 - 0.091 13.2 0.2 0.89 10.0 0.1 2.5 3 0 0 3 3 3 0 Conserved region of unknown function on GLTSCR protein DPM2 PF07297.12 OAG10340.1 - 2.2e-32 111.2 4.1 2.8e-32 110.8 4.1 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 OAG10340.1 - 0.00087 19.2 1.9 0.0012 18.8 1.9 1.2 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 OAG10340.1 - 0.054 13.6 0.5 0.054 13.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) LapA_dom PF06305.11 OAG10340.1 - 1 9.2 4.4 0.29 11.0 0.5 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain COX14 PF14880.6 OAG10340.1 - 1.1 9.2 0.1 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly MA3 PF02847.17 OAG10341.1 - 5.9e-25 87.4 0.0 1.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 OAG10341.1 - 4.9e-10 39.4 3.0 9.4e-10 38.5 3.0 1.5 1 0 0 1 1 1 1 MIF4G domain Herpes_BBRF1 PF04793.12 OAG10341.1 - 0.09 11.8 1.0 0.15 11.1 1.0 1.3 1 0 0 1 1 1 0 BRRF1-like protein Cnd1 PF12717.7 OAG10341.1 - 0.26 11.3 2.1 0.56 10.2 2.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_3 PF01494.19 OAG10342.1 - 5.2e-27 95.0 0.0 8.5e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG10342.1 - 2.9e-05 24.5 0.0 0.0078 16.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG10342.1 - 5.7e-05 22.5 0.0 0.00019 20.8 0.0 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG10342.1 - 0.00031 20.9 0.1 0.00088 19.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG10342.1 - 0.00034 20.3 0.0 0.0065 16.1 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 OAG10342.1 - 0.00039 19.6 0.0 0.00078 18.6 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.14 OAG10342.1 - 0.004 15.9 0.1 0.0058 15.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG10342.1 - 0.0091 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAG10342.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAG10342.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG10342.1 - 0.034 13.5 0.4 0.065 12.6 0.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_M24 PF00557.24 OAG10343.1 - 1.5e-47 162.0 0.1 1.9e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 OAG10343.1 - 2e-17 63.2 12.8 4.8e-17 62.0 12.8 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OAG10343.1 - 0.0045 17.1 10.7 0.0045 17.1 10.7 2.5 2 0 0 2 2 2 1 MYND finger DUF2116 PF09889.9 OAG10343.1 - 0.21 11.6 1.9 0.5 10.4 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PolC_DP2 PF03833.13 OAG10343.1 - 2.9 5.7 4.2 4.2 5.1 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Acetyltransf_10 PF13673.7 OAG10344.1 - 4.5e-11 42.8 0.0 7.6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG10344.1 - 7.3e-11 42.3 0.0 1.3e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG10344.1 - 4.9e-09 36.5 0.0 8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG10344.1 - 3.9e-07 30.2 0.0 1.7e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG10344.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 OAG10344.1 - 0.017 15.2 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4050 PF13259.6 OAG10345.1 - 0.082 13.2 1.4 0.12 12.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) BIV_Env PF05858.12 OAG10345.1 - 0.21 9.7 0.1 0.3 9.2 0.1 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Sugar_tr PF00083.24 OAG10346.1 - 1.3e-36 126.4 8.7 5.5e-27 94.7 6.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG10346.1 - 9.1e-05 21.5 22.2 0.00022 20.3 21.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG10346.1 - 0.00014 20.6 6.4 0.0036 15.9 2.2 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein adh_short PF00106.25 OAG10347.1 - 7.1e-19 68.0 0.1 9.2e-19 67.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10347.1 - 1e-14 54.7 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10347.1 - 3.3e-05 23.9 0.1 4.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG10347.1 - 0.0029 17.1 0.0 0.0049 16.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG10347.1 - 0.022 14.6 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG10347.1 - 0.17 11.3 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2457 PF10446.9 OAG10349.1 - 1.8e-143 479.1 30.9 1.8e-143 479.1 30.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) SpoIIIAH PF12685.7 OAG10349.1 - 0.06 13.2 5.7 0.14 12.0 5.7 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Ank_4 PF13637.6 OAG10350.1 - 0.086 13.5 0.0 0.54 10.9 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) TAXi_C PF14541.6 OAG10350.1 - 0.16 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Ank_3 PF13606.6 OAG10350.1 - 0.18 12.5 0.3 4 8.3 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat GTP_EFTU PF00009.27 OAG10351.1 - 7.7e-60 201.8 0.2 1.4e-59 200.9 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAG10351.1 - 1.4e-33 115.3 0.1 2.8e-33 114.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 OAG10351.1 - 2.5e-33 114.0 0.0 5.7e-33 112.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAG10351.1 - 1.5e-24 85.8 0.0 3.7e-23 81.4 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG10351.1 - 1.7e-13 50.7 0.1 3.6e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAG10351.1 - 5.1e-06 26.3 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF442 PF04273.13 OAG10351.1 - 0.013 15.6 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) ATP_bind_1 PF03029.17 OAG10351.1 - 0.023 14.5 0.7 0.098 12.4 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAG10351.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-RING_2 PF13639.6 OAG10352.1 - 4.1e-12 46.2 5.1 6.5e-12 45.6 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG10352.1 - 8e-09 35.2 4.1 1.2e-08 34.6 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG10352.1 - 1.8e-08 34.5 2.7 3.3e-08 33.7 2.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG10352.1 - 3.8e-08 33.1 3.0 5.9e-08 32.5 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG10352.1 - 9.9e-08 31.6 3.0 9.9e-08 31.6 3.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 OAG10352.1 - 2.6e-07 30.5 2.0 3.9e-07 29.9 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.22 OAG10352.1 - 2.6e-07 30.6 0.0 5.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_3 PF13920.6 OAG10352.1 - 8.4e-06 25.6 2.9 1.2e-05 25.0 2.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG10352.1 - 8.8e-06 25.7 2.2 1.5e-05 24.9 0.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAG10352.1 - 0.00093 19.2 0.8 0.0022 18.0 0.5 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAG10352.1 - 0.0084 16.0 3.1 0.014 15.2 3.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAG10352.1 - 0.029 14.0 2.8 0.06 13.0 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OAG10352.1 - 0.04 14.1 3.3 0.87 9.8 1.0 2.3 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 OAG10352.1 - 0.21 11.8 4.4 0.43 10.8 4.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OAG10352.1 - 0.24 11.6 2.4 0.66 10.2 2.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 OAG10352.1 - 1.5 8.6 2.8 3.6 7.5 2.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MIP PF00230.20 OAG10354.1 - 6.7e-47 160.1 16.5 8.4e-47 159.8 16.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Lipase_GDSL_2 PF13472.6 OAG10355.1 - 3e-21 76.6 1.8 5e-21 75.9 1.8 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG10355.1 - 7e-10 39.2 0.8 1.1e-09 38.6 0.8 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pyr_redox_2 PF07992.14 OAG10356.1 - 4.9e-32 111.3 0.0 6.4e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG10356.1 - 2.1e-11 44.2 0.1 1.8e-09 38.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG10356.1 - 4.2e-05 22.9 0.0 0.00016 21.0 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG10356.1 - 0.0045 15.9 0.1 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Clostridium_P47 PF06597.11 OAG10356.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Clostridium P-47 protein K_oxygenase PF13434.6 OAG10356.1 - 0.2 10.8 0.0 0.6 9.2 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PhzC-PhzF PF02567.16 OAG10357.1 - 3.3e-36 125.2 0.5 2.8e-19 69.7 0.1 2.0 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein WD40 PF00400.32 OAG10358.1 - 3e-08 34.2 7.3 0.0061 17.4 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG10358.1 - 5.1e-05 23.5 0.0 0.16 12.3 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4404 PF14357.6 OAG10358.1 - 1.8 9.2 6.0 4.2 8.1 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) CCDC106 PF15794.5 OAG10358.1 - 9.7 5.8 11.6 15 5.2 11.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ILEI PF15711.5 OAG10360.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Interleukin-like EMT inducer Peptidase_C65 PF10275.9 OAG10361.1 - 2.8e-66 223.5 0.0 3.6e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.27 OAG10362.1 - 1.5e-19 70.4 0.3 3.6e-19 69.2 0.3 1.7 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 OAG10362.1 - 0.098 12.7 1.8 5.6 7.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG10362.1 - 1.6 8.7 4.9 2.8 7.9 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.22 OAG10364.1 - 3.4e-55 186.1 0.0 3.9e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG10364.1 - 5.6e-22 78.2 0.0 1e-21 77.4 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG10364.1 - 6.7e-10 38.7 0.0 9.3e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG10364.1 - 0.0002 20.8 0.0 0.0004 19.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAG10364.1 - 0.00021 20.8 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAG10364.1 - 0.0072 15.5 0.0 0.048 12.8 0.0 1.6 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 OAG10364.1 - 0.026 14.6 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OAG10364.1 - 0.074 13.6 0.0 0.076 13.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 OAG10364.1 - 0.14 12.1 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase HET PF06985.11 OAG10365.1 - 5e-21 75.6 0.1 7.3e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DeoC PF01791.9 OAG10366.1 - 4.9e-11 42.7 1.3 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 2 DeoC/LacD family aldolase His_biosynth PF00977.21 OAG10366.1 - 0.03 13.8 0.1 0.077 12.4 0.1 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 OAG10366.1 - 0.072 12.3 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Ribosomal_S27e PF01667.17 OAG10367.1 - 1e-28 98.8 6.9 1.3e-28 98.5 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 S4 PF01479.25 OAG10368.1 - 2.3e-12 46.4 0.6 2.3e-12 46.4 0.6 2.2 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 OAG10368.1 - 7e-06 26.9 0.1 1.3e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 OAG10368.1 - 0.042 14.0 0.2 4.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 OAG10369.1 - 8.1e-47 157.2 4.4 1.3e-46 156.6 4.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e ABC_tran_Xtn PF12848.7 OAG10369.1 - 0.023 14.7 0.5 0.036 14.1 0.5 1.3 1 0 0 1 1 1 0 ABC transporter Nudix_hydro PF18290.1 OAG10369.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Nudix hydrolase domain Git3 PF11710.8 OAG10371.1 - 1.4e-22 80.5 12.7 3.1e-22 79.4 12.7 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 OAG10371.1 - 6e-06 26.2 1.9 9.8e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 OAG10371.1 - 0.046 12.9 16.7 0.065 12.3 16.7 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor PRRSV_2b PF07069.11 OAG10371.1 - 0.17 12.4 2.4 0.61 10.6 2.4 2.0 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b DUF3552 PF12072.8 OAG10372.1 - 3.6e-05 23.3 13.2 0.0005 19.5 3.4 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) DUF390 PF04094.14 OAG10372.1 - 0.0032 15.9 8.7 0.0044 15.4 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF390) UPF0242 PF06785.11 OAG10372.1 - 0.12 12.5 1.9 0.19 11.8 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 OAG10372.1 - 0.36 11.4 2.7 0.79 10.2 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Ribosomal_L44 PF00935.19 OAG10373.1 - 0.097 13.2 0.8 0.097 13.2 0.8 2.5 2 1 1 3 3 3 0 Ribosomal protein L44 zf-C2H2 PF00096.26 OAG10373.1 - 0.099 13.1 10.0 0.12 12.9 1.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.6 OAG10373.1 - 0.2 11.6 1.4 3.8 7.5 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 OAG10373.1 - 0.24 12.3 8.9 0.52 11.3 1.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Peroxidase_2 PF01328.17 OAG10374.1 - 1.9e-48 165.5 0.0 2.4e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Aldedh PF00171.22 OAG10375.1 - 3.1e-168 560.1 0.4 3.5e-168 559.9 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Kinesin PF00225.23 OAG10376.1 - 2.1e-110 368.8 0.3 6.2e-110 367.2 0.3 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG10376.1 - 1.9e-26 92.8 1.5 2.1e-25 89.4 0.0 3.1 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 OAG10376.1 - 4.2e-07 30.4 0.1 4.2e-07 30.4 0.1 5.4 3 1 1 5 5 5 1 Kinesin-associated microtubule-binding MCC-bdg_PDZ PF10506.9 OAG10376.1 - 0.012 15.6 7.5 0.86 9.7 2.5 3.9 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome RRF_GI PF12614.8 OAG10376.1 - 7.5 6.7 11.5 4 7.6 0.2 4.1 3 0 0 3 3 3 0 Ribosome recycling factor UPF0183 PF03676.14 OAG10377.1 - 6.2e-48 164.0 0.0 2.9e-32 112.4 0.0 3.1 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) DUF3295 PF11702.8 OAG10377.1 - 2.2 7.5 5.0 3.6 6.8 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) tRNA-synt_1 PF00133.22 OAG10378.1 - 3.7e-161 537.4 0.4 4.8e-161 537.0 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAG10378.1 - 4.8e-22 78.2 0.0 8.7e-14 51.1 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAG10378.1 - 4.3e-18 65.7 0.0 8.9e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 OAG10378.1 - 0.0011 18.8 6.3 0.0025 17.6 6.3 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 OAG10378.1 - 0.017 14.5 0.0 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Aldolase_II PF00596.21 OAG10380.1 - 1.7e-33 116.1 0.2 2.6e-33 115.6 0.2 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RhgB_N PF09284.10 OAG10381.1 - 2.9e-110 367.7 6.8 3.9e-110 367.3 6.8 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 OAG10381.1 - 1.6e-40 138.7 0.0 6e-40 136.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 OAG10381.1 - 1.5e-19 69.6 7.0 2.8e-19 68.7 4.6 2.7 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OAG10381.1 - 0.00017 21.8 1.8 0.00017 21.8 1.8 2.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Acylphosphatase PF00708.18 OAG10381.1 - 0.086 13.3 0.0 0.54 10.7 0.0 2.2 3 0 0 3 3 3 0 Acylphosphatase DUF3349 PF11829.8 OAG10382.1 - 0.054 14.3 0.1 8.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Glyco_trans_A_1 PF09318.10 OAG10382.1 - 0.085 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A F-box PF00646.33 OAG10383.1 - 2.7e-06 27.1 0.4 5.4e-06 26.2 0.4 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG10383.1 - 0.00085 19.2 0.7 0.00085 19.2 0.7 2.0 3 0 0 3 3 3 1 F-box-like EphA2_TM PF14575.6 OAG10384.1 - 3.2e-06 27.9 0.8 4.5e-06 27.4 0.8 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SPT_ssu-like PF11779.8 OAG10384.1 - 0.0011 18.5 1.1 0.0018 17.8 1.1 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like MAP17 PF15807.5 OAG10384.1 - 0.0012 19.1 0.1 0.0016 18.7 0.1 1.2 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Amnionless PF14828.6 OAG10384.1 - 0.0027 16.6 0.0 0.0028 16.6 0.0 1.0 1 0 0 1 1 1 1 Amnionless RCR PF12273.8 OAG10384.1 - 0.0029 18.2 0.0 0.0043 17.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4330 PF14221.6 OAG10384.1 - 0.0044 17.2 0.6 0.0054 17.0 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4330) SARAF PF06682.12 OAG10384.1 - 0.0047 16.6 0.0 0.0051 16.5 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis tRNA_anti-like PF12869.7 OAG10384.1 - 0.0053 16.4 0.1 0.0063 16.2 0.1 1.1 1 0 0 1 1 1 1 tRNA_anti-like TMEM154 PF15102.6 OAG10384.1 - 0.0058 16.5 0.3 0.0074 16.2 0.3 1.1 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 OAG10384.1 - 0.0064 16.8 0.0 0.0071 16.6 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Protocadherin PF08374.11 OAG10384.1 - 0.0065 16.5 0.1 0.0075 16.3 0.1 1.2 1 0 0 1 1 1 1 Protocadherin DUF4381 PF14316.6 OAG10384.1 - 0.0071 16.6 0.6 0.0097 16.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF4834 PF16118.5 OAG10384.1 - 0.011 16.7 0.0 0.014 16.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2681 PF10883.8 OAG10384.1 - 0.011 16.1 3.0 0.015 15.6 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Comm PF15957.5 OAG10384.1 - 0.012 16.0 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 Commissureless ECSCR PF15820.5 OAG10384.1 - 0.019 14.8 0.2 0.026 14.3 0.2 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Insulin_TMD PF17870.1 OAG10384.1 - 0.022 14.8 1.2 0.033 14.3 1.2 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Tmemb_9 PF05434.11 OAG10384.1 - 0.023 14.6 0.3 0.028 14.3 0.3 1.1 1 0 0 1 1 1 0 TMEM9 DUF3552 PF12072.8 OAG10384.1 - 0.025 14.0 0.6 0.03 13.7 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Cadherin_C_2 PF16492.5 OAG10384.1 - 0.027 15.2 0.2 0.038 14.7 0.2 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Herpes_glycop PF01528.16 OAG10384.1 - 0.032 13.1 2.2 0.037 12.9 2.2 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M 7TM_GPCR_Srx PF10328.9 OAG10384.1 - 0.034 13.8 0.4 0.04 13.5 0.4 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx TMEM132D_C PF15706.5 OAG10384.1 - 0.039 13.7 0.7 0.059 13.2 0.7 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term WBP-1 PF11669.8 OAG10384.1 - 0.045 14.4 2.4 0.074 13.7 2.4 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 DUF2615 PF11027.8 OAG10384.1 - 0.046 13.9 0.1 0.064 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) V_ATPase_I PF01496.19 OAG10384.1 - 0.056 11.4 0.2 0.062 11.2 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sigma_reg_N PF13800.6 OAG10384.1 - 0.057 13.7 0.1 0.073 13.4 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal MscL PF01741.18 OAG10384.1 - 0.057 13.7 0.2 0.069 13.5 0.2 1.1 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL TMEM51 PF15345.6 OAG10384.1 - 0.06 13.2 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ASFV_J13L PF05568.11 OAG10384.1 - 0.065 13.0 0.1 0.075 12.8 0.1 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein GAPT PF11770.8 OAG10384.1 - 0.067 13.1 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) OSTbeta PF15048.6 OAG10384.1 - 0.072 13.2 0.1 0.094 12.9 0.1 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein LST1 PF05083.13 OAG10384.1 - 0.073 13.4 0.6 0.11 12.8 0.6 1.3 1 0 0 1 1 1 0 LST-1 protein DUF3357 PF11837.8 OAG10384.1 - 0.075 13.5 0.2 0.1 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) MscS_TM PF12794.7 OAG10384.1 - 0.079 11.8 1.0 0.1 11.5 1.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3328 PF11807.8 OAG10384.1 - 0.082 12.7 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DAP10 PF07213.11 OAG10384.1 - 0.087 12.8 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 DAP10 membrane protein DUF929 PF06053.11 OAG10384.1 - 0.088 12.1 1.5 0.11 11.8 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) FAM176 PF14851.6 OAG10384.1 - 0.089 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 FAM176 family RIFIN PF02009.16 OAG10384.1 - 0.09 12.7 6.1 0.082 12.8 5.4 1.3 1 1 0 1 1 1 0 Rifin Chordopox_A13L PF05961.11 OAG10384.1 - 0.094 13.0 0.5 0.16 12.2 0.5 1.5 1 1 0 1 1 1 0 Chordopoxvirus A13L protein Sarcoglycan_2 PF05510.13 OAG10384.1 - 0.12 11.2 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Med3 PF11593.8 OAG10384.1 - 0.14 11.3 6.6 0.17 11.1 6.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Baculo_11_kDa PF06143.11 OAG10384.1 - 0.28 10.8 3.9 0.45 10.1 3.9 1.4 1 1 0 1 1 1 0 Baculovirus 11 kDa family HemY_N PF07219.13 OAG10384.1 - 0.88 9.8 5.8 1.9 8.7 5.8 1.5 1 1 0 1 1 1 0 HemY protein N-terminus DAG1 PF05454.11 OAG10384.1 - 1.5 8.1 5.6 1.8 7.9 5.6 1.4 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Kelch_3 PF13415.6 OAG10385.1 - 1.8e-15 56.8 5.0 4.4e-11 42.8 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG10385.1 - 1.4e-14 53.9 0.1 1.5e-05 24.9 0.0 4.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG10385.1 - 1.1e-12 47.6 0.9 0.00022 21.1 0.2 4.0 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 OAG10385.1 - 2.9e-12 46.0 0.0 0.0012 18.4 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 OAG10385.1 - 2.9e-08 33.7 4.4 0.046 14.0 0.0 5.3 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OAG10385.1 - 6.3e-07 29.1 0.2 0.00073 19.4 0.0 4.3 4 0 0 4 4 4 1 Kelch motif BTB PF00651.31 OAG10385.1 - 0.25 11.6 0.0 0.8 10.0 0.1 1.7 2 0 0 2 2 2 0 BTB/POZ domain AhpC-TSA PF00578.21 OAG10387.1 - 7.1e-32 109.9 0.0 9.9e-32 109.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG10387.1 - 1.5e-13 50.7 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OAG10387.1 - 6.6e-11 41.9 0.1 1.2e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.16 OAG10388.1 - 1.3e-40 139.5 32.9 1.3e-40 139.5 32.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG10388.1 - 1.7e-07 30.5 11.1 1.7e-07 30.5 11.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG10388.1 - 1.8e-06 26.7 4.7 3.4e-06 25.8 4.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.6 OAG10388.1 - 1.3 9.5 5.8 0.48 10.9 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PQ-loop PF04193.14 OAG10389.1 - 2.7e-23 81.5 6.5 2.6e-13 49.5 1.0 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 OAG10389.1 - 0.046 13.8 1.2 0.27 11.3 0.4 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Polyketide_cyc2 PF10604.9 OAG10392.1 - 1.4e-05 25.4 0.1 4.3e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OAG10392.1 - 9.1e-05 22.7 0.4 0.00015 22.0 0.4 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Kelch_1 PF01344.25 OAG10393.1 - 1.1e-32 111.3 7.6 5.5e-06 25.9 0.1 7.4 7 1 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 OAG10393.1 - 1.4e-25 88.6 12.2 3.2e-05 24.1 0.0 7.2 3 3 4 7 7 7 5 Kelch motif Kelch_3 PF13415.6 OAG10393.1 - 2e-24 85.3 10.1 5.1e-05 23.5 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG10393.1 - 2.4e-24 85.0 4.4 5.1e-06 26.4 0.0 6.0 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG10393.1 - 1.2e-13 50.7 1.0 0.41 10.7 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OAG10393.1 - 1.1e-05 25.1 12.1 0.94 9.6 0.0 7.8 7 4 0 7 7 7 2 Kelch motif PQQ_3 PF13570.6 OAG10393.1 - 0.0025 18.2 3.8 3.3 8.3 0.0 4.4 5 0 0 5 5 5 2 PQQ-like domain MARVEL PF01284.23 OAG10394.1 - 0.00023 21.2 15.2 0.00036 20.6 15.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4199 PF13858.6 OAG10394.1 - 1.5 9.2 10.2 2.4 8.5 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Ribosomal_L36 PF00444.18 OAG10396.1 - 1.1e-17 63.9 12.2 1.6e-17 63.4 12.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 SSV1_ORF_D-335 PF07935.11 OAG10396.1 - 0.016 15.5 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 ORF D-335-like protein NMT_C PF02799.15 OAG10397.1 - 5.6e-87 290.6 0.0 9.3e-87 289.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 OAG10397.1 - 1.9e-76 255.4 0.5 6.5e-74 247.1 0.0 2.1 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 OAG10397.1 - 2.4e-06 27.6 0.1 3.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG10397.1 - 0.0048 17.1 0.1 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family NTP_transf_9 PF04248.12 OAG10397.1 - 0.045 13.6 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF427) PGA2 PF07543.12 OAG10397.1 - 2.5 8.1 6.2 4.7 7.2 6.2 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Trp_oprn_chp PF09534.10 OAG10398.1 - 0.01 15.7 2.3 0.016 15.0 2.3 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PepSY_TM PF03929.16 OAG10398.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Amnionless PF14828.6 OAG10398.1 - 0.021 13.7 0.1 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 Amnionless PsbX PF06596.11 OAG10398.1 - 0.025 14.6 6.3 0.046 13.7 6.3 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) EphA2_TM PF14575.6 OAG10398.1 - 0.078 13.9 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2627 PF11118.8 OAG10398.1 - 0.081 13.5 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) BT1 PF03092.16 OAG10398.1 - 0.18 10.0 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 BT1 family PTP_tm PF18861.1 OAG10398.1 - 0.2 11.6 4.0 0.26 11.2 1.9 1.9 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 OAG10398.1 - 0.57 10.8 6.0 1.7 9.3 3.6 2.5 2 1 0 2 2 2 0 Small Novel Rich in Cartilage DUF515 PF04415.12 OAG10398.1 - 1.2 7.4 4.5 1.8 6.9 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Sugar_tr PF00083.24 OAG10399.1 - 3.7e-100 335.9 24.2 4.3e-100 335.7 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10399.1 - 2.8e-13 49.5 33.0 1e-09 37.8 9.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily His_Phos_2 PF00328.22 OAG10400.1 - 0.012 14.9 0.0 0.36 10.1 0.0 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) DUF2967 PF11179.8 OAG10401.1 - 5.6 4.9 8.7 5.5 5.0 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Asp PF00026.23 OAG10403.1 - 2.3e-11 43.7 0.0 3.8e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TraL PF07178.11 OAG10403.1 - 0.032 14.7 0.1 0.082 13.4 0.1 1.6 1 0 0 1 1 1 0 TraL protein Adeno_E3_CR2 PF02439.15 OAG10403.1 - 0.042 13.6 1.1 0.11 12.3 1.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OAG10403.1 - 0.087 13.7 0.1 0.24 12.3 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 OAG10403.1 - 0.092 11.6 1.1 0.13 11.0 1.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Amnionless PF14828.6 OAG10403.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4307 PF14155.6 OAG10403.1 - 0.19 11.6 1.2 3.2 7.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF202 PF02656.15 OAG10403.1 - 0.27 11.7 2.1 0.88 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) FeoB_associated PF12669.7 OAG10403.1 - 0.59 10.6 4.3 0.8 10.2 1.5 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Syndecan PF01034.20 OAG10403.1 - 9.2 6.3 9.0 0.075 13.0 0.7 1.8 2 0 0 2 2 2 0 Syndecan domain MFS_1 PF07690.16 OAG10406.1 - 1.6e-26 93.1 37.1 1.6e-26 93.1 37.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5389 PF17364.2 OAG10406.1 - 0.14 12.2 2.6 0.65 10.1 1.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5389) FHA PF00498.26 OAG10407.1 - 1.4e-17 63.7 0.1 5.3e-17 61.9 0.1 2.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG10407.1 - 4e-05 23.9 0.3 0.00036 20.8 0.0 2.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 OAG10407.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 YhfZ C-terminal domain Hormone_1 PF00103.20 OAG10407.1 - 0.014 15.2 1.3 0.014 15.2 1.3 1.7 2 0 0 2 2 2 0 Somatotropin hormone family DUF4140 PF13600.6 OAG10407.1 - 4.3 7.8 17.0 11 6.5 2.4 3.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Romo1 PF10247.9 OAG10408.1 - 2.2e-26 92.0 13.0 3.2e-26 91.5 13.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 OAG10408.1 - 0.011 16.1 3.0 0.015 15.7 3.0 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_61 PF03443.14 OAG10410.1 - 4.3e-64 216.2 0.1 5.2e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4469 PF14734.6 OAG10410.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold UbiA PF01040.18 OAG10411.1 - 4.8e-60 203.0 13.8 4.8e-60 203.0 13.8 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family RPN2_C PF18004.1 OAG10412.1 - 3.9e-55 186.1 8.1 3.9e-55 186.1 8.1 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 OAG10412.1 - 1.9e-36 122.7 21.8 5.2e-10 39.2 0.0 8.4 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAG10412.1 - 8e-20 71.0 0.3 2e-14 53.7 0.0 4.9 4 1 3 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 OAG10412.1 - 5.7e-06 26.7 0.1 0.0083 16.6 0.0 4.4 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 OAG10412.1 - 0.00037 20.5 0.1 9.6 6.8 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 OAG10412.1 - 0.012 15.7 0.6 1.7 8.7 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 OAG10412.1 - 0.06 13.9 0.1 61 4.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG10412.1 - 0.21 11.8 0.8 11 6.3 0.1 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 mRNA_triPase PF02940.15 OAG10413.1 - 1.4e-47 162.3 1.3 2e-47 161.7 1.3 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CNRIP1 PF15043.6 OAG10413.1 - 0.0032 17.0 0.3 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 CB1 cannabinoid receptor-interacting protein 1 Trypan_PARP PF05887.11 OAG10413.1 - 0.49 10.4 3.8 0.94 9.5 3.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ndc1_Nup PF09531.10 OAG10413.1 - 3.5 6.2 8.1 5.8 5.5 8.1 1.5 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PK PF00224.21 OAG10414.1 - 3.9e-172 571.9 4.3 4.8e-172 571.6 4.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OAG10414.1 - 1.1e-37 128.8 0.0 2.8e-37 127.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OAG10414.1 - 0.0016 17.6 0.3 0.0049 16.0 0.1 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 OAG10414.1 - 0.016 14.2 0.0 0.068 12.2 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.10 OAG10415.1 - 6e-33 112.6 0.0 6.7e-33 112.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) NIBRIN_BRCT_II PF16508.5 OAG10416.1 - 1.9e-31 108.9 0.0 1e-30 106.5 0.0 2.4 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 OAG10416.1 - 0.0019 18.5 0.1 0.0052 17.1 0.1 1.7 1 0 0 1 1 1 1 FHA domain IBR PF01485.21 OAG10417.1 - 5.1e-21 74.7 33.2 1e-11 44.9 9.6 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OAG10417.1 - 0.0011 19.3 6.7 0.0011 19.3 6.7 3.7 3 1 0 3 3 3 1 Ring finger domain Ntox3 PF15536.6 OAG10417.1 - 0.047 13.7 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 3 zf-RING_14 PF17978.1 OAG10417.1 - 0.29 11.6 16.7 0.074 13.5 1.9 3.8 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain ERG4_ERG24 PF01222.17 OAG10418.1 - 3.7e-137 457.6 21.2 4.6e-137 457.3 21.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ELP6 PF09807.9 OAG10419.1 - 3e-09 36.7 0.0 5.9e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 RdRP PF05183.12 OAG10420.1 - 5.7e-173 576.7 0.1 8.2e-173 576.2 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase hnRNP_Q_AcD PF18360.1 OAG10420.1 - 0.0091 15.9 0.3 0.14 12.1 0.1 2.4 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF812 PF05667.11 OAG10421.1 - 0.0023 16.9 45.7 0.013 14.4 16.8 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.7 OAG10421.1 - 0.0079 16.4 23.5 0.0079 16.4 23.5 4.6 1 1 2 4 4 3 1 Tropomyosin like WEMBL PF05701.11 OAG10421.1 - 0.027 13.2 44.4 0.066 11.9 44.3 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Spc7 PF08317.11 OAG10421.1 - 0.036 13.0 51.0 0.081 11.8 12.7 3.4 1 1 1 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 OAG10421.1 - 0.084 12.4 49.4 0.17 11.4 25.5 3.2 1 1 2 3 3 3 0 Intermediate filament protein Pdase_M17_N2 PF18295.1 OAG10421.1 - 0.15 12.3 3.3 0.13 12.5 0.4 2.4 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 FRP PF18032.1 OAG10421.1 - 0.21 12.2 4.1 17 6.1 0.3 3.3 3 0 0 3 3 3 0 Photoprotection regulator fluorescence recovery protein KxDL PF10241.9 OAG10421.1 - 0.49 10.7 28.0 0.018 15.3 4.1 5.5 3 1 2 5 5 5 0 Uncharacterized conserved protein Tropomyosin PF00261.20 OAG10421.1 - 0.7 9.2 43.5 0.038 13.3 20.2 3.6 1 1 1 3 3 2 0 Tropomyosin CENP-F_leu_zip PF10473.9 OAG10421.1 - 1 9.4 49.9 0.85 9.6 4.2 4.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 OAG10421.1 - 1.1 7.8 38.0 0.58 8.7 14.2 2.9 1 1 2 3 3 3 0 AAA domain PspA_IM30 PF04012.12 OAG10421.1 - 2.7 7.5 47.3 0.73 9.4 14.1 4.2 1 1 3 4 4 4 0 PspA/IM30 family DUF1664 PF07889.12 OAG10421.1 - 3.5 7.7 22.7 10 6.2 0.7 4.9 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 OAG10421.1 - 6.8 6.4 39.9 0.16 11.7 3.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) FAD-oxidase_C PF02913.19 OAG10422.1 - 4.3e-65 219.8 0.1 5.7e-65 219.4 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG10422.1 - 2.2e-31 108.5 0.0 4.3e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain MR_MLE_C PF13378.6 OAG10422.1 - 0.078 12.5 0.2 1.6 8.3 0.0 2.5 3 0 0 3 3 3 0 Enolase C-terminal domain-like Semialdhyde_dhC PF02774.18 OAG10423.1 - 8.1e-40 136.9 0.0 1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OAG10423.1 - 1e-29 103.4 0.0 2.9e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 OAG10423.1 - 0.056 14.2 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 OAG10423.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OAG10423.1 - 0.13 12.3 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_S4e PF00900.20 OAG10424.1 - 1.6e-35 120.9 0.1 3.3e-35 119.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 OAG10424.1 - 2.2e-23 81.6 0.1 3.8e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OAG10424.1 - 1.4e-17 63.5 6.5 2.7e-17 62.6 6.5 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 OAG10424.1 - 5.3e-08 32.4 0.1 1.1e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 OAG10424.1 - 0.00013 21.7 4.4 0.00013 21.7 4.4 3.1 4 0 0 4 4 4 1 KOW motif SUR7 PF06687.12 OAG10425.1 - 3.1e-27 95.6 8.8 4.3e-27 95.1 8.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 OAG10425.1 - 0.19 12.2 0.1 0.74 10.3 0.0 2.1 2 0 0 2 2 2 0 SCIMP protein DUF4381 PF14316.6 OAG10425.1 - 0.2 11.9 0.2 0.38 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pox_P21 PF05313.12 OAG10425.1 - 0.36 10.4 0.8 0.59 9.7 0.8 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein MMM1 PF10296.9 OAG10426.1 - 0.00025 20.2 0.2 0.001 18.2 0.0 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 OAG10426.1 - 0.031 14.8 0.0 0.076 13.5 0.0 1.7 2 0 0 2 2 2 0 PH domain SUR7 PF06687.12 OAG10427.1 - 7.1e-37 127.1 6.3 8.5e-37 126.8 6.3 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF373 PF04123.13 OAG10427.1 - 0.016 14.7 3.2 0.04 13.4 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Clc-like PF07062.12 OAG10427.1 - 0.27 10.7 5.4 0.41 10.1 5.4 1.3 1 0 0 1 1 1 0 Clc-like Fig1 PF12351.8 OAG10427.1 - 0.43 10.5 10.3 0.79 9.6 10.3 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Rogdi_lz PF10259.9 OAG10428.1 - 6.1e-90 301.3 0.0 6.9e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein TP_methylase PF00590.20 OAG10429.1 - 7.8e-53 179.6 0.3 1.6e-51 175.3 0.1 2.1 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 OAG10429.1 - 5.1e-13 49.4 0.0 1.1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 OAG10429.1 - 2.1e-11 43.0 0.1 4.7e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 OAG10429.1 - 2.7e-11 42.9 0.2 3.9e-10 39.2 0.2 2.3 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal SAICAR_synt PF01259.18 OAG10430.1 - 2.4e-97 325.5 0.0 2.8e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Atg29_N PF18388.1 OAG10431.1 - 8.7e-21 73.5 0.6 1.7e-20 72.6 0.6 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain HTH_OrfB_IS605 PF12323.8 OAG10432.1 - 0.71 9.4 4.6 1.3 8.6 1.4 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain HMG_box PF00505.19 OAG10433.1 - 9.5e-21 74.0 1.3 1.7e-20 73.2 1.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG10433.1 - 4.3e-10 40.0 0.8 7.7e-10 39.2 0.8 1.4 1 0 0 1 1 1 1 HMG-box domain Med3 PF11593.8 OAG10433.1 - 1.3 8.2 4.0 4 6.5 0.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Exo_endo_phos PF03372.23 OAG10434.1 - 3.6e-12 46.3 0.0 6.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OAG10434.1 - 0.015 15.1 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase zf-GRF PF06839.12 OAG10434.1 - 0.018 15.1 5.6 0.045 13.8 5.6 1.7 1 1 0 1 1 1 0 GRF zinc finger TilS_C PF11734.8 OAG10434.1 - 0.073 12.5 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 TilS substrate C-terminal domain COX6A PF02046.15 OAG10435.1 - 1.5e-46 157.4 0.4 1.8e-46 157.2 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANAPC5 PF12862.7 OAG10436.1 - 1.6e-28 98.6 8.6 1.9e-28 98.4 5.8 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 OAG10436.1 - 0.045 13.5 0.2 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 OAG10436.1 - 4.3 7.7 23.3 1.2 9.4 0.3 5.9 4 1 3 7 7 7 0 Tetratricopeptide repeat CIA30 PF08547.12 OAG10437.1 - 2.2e-43 148.1 0.0 2.9e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Mito_carr PF00153.27 OAG10438.1 - 2.4e-72 239.0 4.5 3.5e-23 81.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MBA1 PF07961.11 OAG10439.1 - 1.1e-09 37.7 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 OAG10439.1 - 0.0004 20.5 0.2 0.0032 17.6 0.2 2.1 1 1 0 1 1 1 1 Tim44-like domain UPF0139 PF03669.13 OAG10440.1 - 3.5e-06 26.8 0.1 4.2e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF308 PF03729.13 OAG10440.1 - 0.041 14.2 0.6 0.051 13.9 0.6 1.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Med12 PF09497.10 OAG10441.1 - 3.7e-25 88.0 0.6 8.3e-25 86.9 0.1 1.9 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Ribosomal_S8 PF00410.19 OAG10443.1 - 6e-15 55.3 0.0 2.9e-13 49.9 0.0 2.7 1 1 0 1 1 1 1 Ribosomal protein S8 TLD PF07534.16 OAG10444.1 - 1.3e-28 99.9 0.0 4.6e-28 98.2 0.0 1.8 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 OAG10444.1 - 1.3e-16 61.4 0.3 2.5e-16 60.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function MGC-24 PF05283.11 OAG10445.1 - 4.2e-05 24.0 0.5 6.7e-05 23.4 0.5 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_transf_22 PF03901.17 OAG10445.1 - 0.063 12.5 0.1 0.081 12.1 0.1 1.0 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family DUF5305 PF17231.2 OAG10445.1 - 0.099 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Gelsolin PF00626.22 OAG10445.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Gelsolin repeat Herpes_gE PF02480.16 OAG10445.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.6 OAG10445.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 OAG10445.1 - 0.15 13.0 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TraL PF07178.11 OAG10445.1 - 0.15 12.5 0.1 0.25 11.8 0.1 1.2 1 0 0 1 1 1 0 TraL protein Acyl-CoA_dh_1 PF00441.24 OAG10446.1 - 1.5e-23 83.7 2.5 2.9e-23 82.8 2.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG10446.1 - 1.5e-08 35.3 0.1 1e-07 32.6 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG10446.1 - 2.3e-08 34.1 0.1 5.2e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG10446.1 - 2.4e-07 31.1 6.1 2.4e-07 31.1 6.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PduV-EutP PF10662.9 OAG10446.1 - 0.079 12.7 0.0 6.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0020 PF01170.18 OAG10446.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 AA_permease PF00324.21 OAG10447.1 - 1.1e-148 495.9 37.0 1.2e-148 495.7 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG10447.1 - 2.3e-35 122.2 41.5 3.1e-35 121.9 41.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 OAG10447.1 - 0.016 14.1 0.7 0.026 13.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) RhoGAP PF00620.27 OAG10448.1 - 9.1e-49 165.2 0.0 2.1e-48 164.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 OAG10448.1 - 6.6e-11 42.3 0.4 1.9e-10 40.9 0.4 1.8 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Putative_PNPOx PF01243.20 OAG10449.1 - 5.9e-10 39.2 0.0 1.4e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 OAG10449.1 - 0.12 12.3 0.0 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase IPI_T4 PF11634.8 OAG10449.1 - 0.16 12.0 0.2 0.94 9.5 0.0 2.1 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 SPT16 PF08644.11 OAG10450.1 - 1.8e-54 184.1 0.3 1.8e-54 184.1 0.3 3.2 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OAG10450.1 - 2.6e-49 167.1 0.2 1.7e-48 164.5 0.2 2.5 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OAG10450.1 - 9.7e-27 94.0 0.0 1.6e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OAG10450.1 - 9.3e-17 61.2 0.2 5.5e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Mito_carr PF00153.27 OAG10451.1 - 1.5e-16 60.1 2.7 6.6e-12 45.2 0.2 2.9 3 1 0 3 3 3 2 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.19 OAG10453.1 - 6.5e-42 142.9 0.0 2.1e-40 138.0 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG10453.1 - 8.7e-12 44.9 0.0 8e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PHP_C PF13263.6 OAG10453.1 - 0.017 14.9 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 0 PHP-associated Gp_dh_N PF00044.24 OAG10453.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.24 OAG10454.1 - 2.3e-84 283.8 19.2 3e-84 283.5 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10454.1 - 1.9e-33 115.9 17.8 1.9e-33 115.9 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 OAG10454.1 - 0.0088 16.2 12.4 0.01 16.0 4.6 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3792) YMF19 PF02326.15 OAG10454.1 - 0.47 11.3 3.3 1.5 9.6 3.1 1.9 2 0 0 2 2 2 0 Plant ATP synthase F0 nlz1 PF12402.8 OAG10454.1 - 0.65 10.5 4.4 0.82 10.1 1.4 2.8 2 1 0 2 2 2 0 NocA-like zinc-finger protein 1 RSN1_7TM PF02714.15 OAG10455.1 - 3.9e-79 265.8 16.2 3.9e-79 265.8 16.2 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG10455.1 - 3.4e-40 137.3 2.8 8.4e-40 136.1 2.8 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAG10455.1 - 7.8e-25 86.9 1.0 1.9e-24 85.7 1.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 OAG10455.1 - 2.2e-24 86.7 0.1 4e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PRF PF06875.11 OAG10455.1 - 0.12 11.8 0.2 0.47 9.9 0.1 1.9 2 0 0 2 2 2 0 Plethodontid receptivity factor PRF WD40 PF00400.32 OAG10456.1 - 2.8e-10 40.6 5.1 0.58 11.1 0.0 8.3 9 0 0 9 9 9 3 WD domain, G-beta repeat PQQ_2 PF13360.6 OAG10456.1 - 0.00043 19.9 0.2 0.58 9.7 0.0 3.2 2 1 2 4 4 4 3 PQQ-like domain CblD PF07434.11 OAG10456.1 - 0.012 14.6 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator Ge1_WD40 PF16529.5 OAG10456.1 - 0.035 13.1 0.1 8.2 5.3 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rad4 PF03835.15 OAG10457.1 - 4.3e-15 55.7 1.4 7.6e-15 54.9 1.4 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 OAG10457.1 - 5.8e-12 46.0 2.7 5.8e-12 46.0 2.7 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily SUR7 PF06687.12 OAG10458.1 - 7e-42 143.4 4.9 8.4e-42 143.2 4.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF373 PF04123.13 OAG10458.1 - 0.044 13.2 3.6 0.065 12.7 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Saf_2TM PF18303.1 OAG10458.1 - 1.3 8.6 4.5 0.93 9.1 1.1 2.1 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Hydrolase_4 PF12146.8 OAG10459.1 - 9.3e-15 54.5 0.0 4e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG10459.1 - 9.7e-14 51.6 0.1 5.8e-12 45.8 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG10459.1 - 2.4e-12 47.9 0.6 4.6e-12 47.0 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAG10459.1 - 0.00063 19.9 0.0 0.00098 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 OAG10459.1 - 0.012 15.5 0.0 1 9.1 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 OAG10459.1 - 0.067 13.1 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fe-ADH PF00465.19 OAG10459.1 - 0.14 11.0 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Lipase_3 PF01764.25 OAG10459.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAP2 PF01569.21 OAG10460.1 - 3.4e-28 98.1 0.3 3.4e-28 98.1 0.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OAG10460.1 - 3.1 7.5 10.0 0.42 10.3 1.6 2.8 2 2 0 2 2 2 0 PAP2 superfamily ATP-synt_DE_N PF02823.16 OAG10463.1 - 8e-18 64.1 0.0 1.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Glyco_hydro_43 PF04616.14 OAG10464.1 - 1e-31 110.4 1.7 1.3e-31 110.0 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAG10464.1 - 0.0056 16.3 0.3 0.0092 15.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain PCI PF01399.27 OAG10465.1 - 3.6e-10 40.3 0.5 1.9e-09 37.9 0.0 2.5 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.22 OAG10466.1 - 1.8e-20 72.7 0.1 2.1e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 GGL domain HLH PF00010.26 OAG10467.1 - 7.1e-13 48.3 0.4 1.6e-12 47.2 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAM76 PF16046.5 OAG10467.1 - 0.0032 16.9 6.0 0.0057 16.1 6.0 1.3 1 0 0 1 1 1 1 FAM76 protein ZapB PF06005.12 OAG10467.1 - 0.01 16.3 1.3 0.031 14.7 1.3 1.8 1 0 0 1 1 1 0 Cell division protein ZapB Med28 PF11594.8 OAG10467.1 - 0.013 15.6 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 28 Csm1_N PF18504.1 OAG10467.1 - 0.15 12.4 2.8 0.65 10.4 2.5 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4407 PF14362.6 OAG10467.1 - 0.62 9.4 4.2 1 8.7 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OAG10467.1 - 1.2 8.1 9.3 2.1 7.3 9.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MerR-DNA-bind PF09278.11 OAG10467.1 - 1.9 9.1 4.7 1e+02 3.6 4.8 2.7 1 1 1 2 2 2 0 MerR, DNA binding DUF3425 PF11905.8 OAG10468.1 - 4e-16 59.1 0.0 6.9e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG10468.1 - 0.011 15.9 9.2 0.023 14.8 9.2 1.6 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OAG10468.1 - 0.11 12.6 9.5 3.7 7.7 7.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper ECH_1 PF00378.20 OAG10469.1 - 1.8e-53 181.4 0.0 2.4e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG10469.1 - 1.5e-24 87.2 0.0 2.5e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG10469.1 - 0.0042 17.0 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 MARVEL PF01284.23 OAG10470.1 - 0.00071 19.6 6.8 0.0013 18.8 6.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain UNC-93 PF05978.16 OAG10470.1 - 0.0023 17.6 1.8 0.0055 16.4 1.8 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 PAF-AH_p_II PF03403.13 OAG10471.1 - 2.1e-13 49.6 0.0 5.5e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 OAG10471.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 OAG10471.1 - 0.0049 16.5 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 OAG10471.1 - 0.0067 15.7 0.1 0.8 8.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG10471.1 - 0.088 13.4 0.1 0.16 12.5 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 OAG10471.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 OAG10471.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein NAD_binding_1 PF00175.21 OAG10472.1 - 3.8e-07 30.7 0.0 0.0053 17.4 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG10472.1 - 0.0031 17.6 0.0 0.1 12.7 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Hydrolase_4 PF12146.8 OAG10473.1 - 2.8e-57 193.8 0.0 3.3e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG10473.1 - 2.6e-14 54.4 0.0 3.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG10473.1 - 2.5e-13 50.3 0.0 2.9e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 OAG10473.1 - 0.0097 15.0 0.0 0.022 13.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 OAG10473.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG10473.1 - 0.21 10.5 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Cation_efflux PF01545.21 OAG10474.1 - 2.8e-50 170.8 4.7 3.4e-50 170.5 4.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG10474.1 - 0.00016 21.8 0.1 0.00033 20.7 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FGGY_C PF02782.16 OAG10475.1 - 1e-27 97.2 0.0 1.5e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG10475.1 - 9e-18 64.7 0.0 9.2e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain adh_short PF00106.25 OAG10476.1 - 5.5e-36 123.9 0.0 7.4e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10476.1 - 1.3e-22 80.5 0.0 2.5e-22 79.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10476.1 - 6.7e-08 32.6 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG10476.1 - 0.00044 19.8 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG10476.1 - 0.0038 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DNA_ligase_A_C PF04679.15 OAG10476.1 - 0.097 13.3 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region PSDC PF12588.8 OAG10477.1 - 5.1e-61 204.7 0.0 8.3e-61 204.0 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 OAG10477.1 - 5.8e-36 123.9 0.0 1e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 OAG10477.1 - 0.002 17.9 0.4 2.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like Glyco_hydro_71 PF03659.14 OAG10478.1 - 7.2e-129 429.9 6.9 1e-128 429.4 6.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Cyclin_N PF00134.23 OAG10480.1 - 2.4e-37 127.5 0.3 4.5e-37 126.6 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG10480.1 - 2.8e-11 43.5 1.1 6.3e-11 42.4 0.4 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cu-oxidase_3 PF07732.15 OAG10481.1 - 1.5e-45 154.1 3.7 4.8e-45 152.4 1.5 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG10481.1 - 1.2e-39 135.2 10.8 2.4e-35 121.3 0.4 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG10481.1 - 6.4e-28 97.9 0.0 6.5e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Monooxygenase_B PF04744.12 OAG10481.1 - 0.028 13.3 0.1 0.048 12.5 0.1 1.3 1 0 0 1 1 1 0 Monooxygenase subunit B protein Phosphoesterase PF04185.14 OAG10482.1 - 1.5e-34 119.8 2.7 1.1e-33 116.9 2.5 2.3 1 1 1 2 2 2 1 Phosphoesterase family Sulfatase PF00884.23 OAG10482.1 - 0.00017 21.1 0.2 0.00025 20.5 0.2 1.2 1 0 0 1 1 1 1 Sulfatase MGC-24 PF05283.11 OAG10483.1 - 0.002 18.6 3.7 0.002 18.6 3.7 2.1 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin SKG6 PF08693.10 OAG10483.1 - 0.0031 16.9 4.4 0.0031 16.9 4.4 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 OAG10483.1 - 0.029 13.8 0.1 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF5325 PF17259.2 OAG10483.1 - 0.074 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5325) DUF4366 PF14283.6 OAG10483.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Rab5ip PF07019.12 OAG10483.1 - 0.16 12.6 0.2 0.31 11.6 0.2 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF2561 PF10812.8 OAG10483.1 - 0.23 11.5 0.9 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) PHZA_PHZB PF03284.13 OAG10483.1 - 0.23 11.1 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B Macoilin PF09726.9 OAG10483.1 - 0.35 9.4 0.4 0.44 9.1 0.4 1.0 1 0 0 1 1 1 0 Macoilin family Alpha_GJ PF03229.13 OAG10483.1 - 3.6 8.2 8.3 0.35 11.4 3.0 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J Sporozoite_P67 PF05642.11 OAG10483.1 - 5.3 5.0 9.5 6.6 4.7 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spc7 PF08317.11 OAG10484.1 - 1.5e-106 355.8 13.9 2.1e-106 355.3 13.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 OAG10484.1 - 1.6e-63 215.4 102.7 1.6e-29 102.9 12.7 7.8 3 1 2 5 5 5 4 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.6 OAG10484.1 - 6e-21 74.3 0.0 1.3e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Spc7_C2 KxDL PF10241.9 OAG10484.1 - 0.01 16.1 2.6 0.21 11.9 4.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 OAG10484.1 - 0.83 10.2 7.2 8 7.1 5.3 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TBCA PF02970.16 OAG10484.1 - 0.87 10.0 13.6 7.6 6.9 1.1 3.8 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF1664 PF07889.12 OAG10484.1 - 1.9 8.5 5.4 5.9 7.0 4.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 OAG10484.1 - 2.5 6.6 5.2 4.5 5.8 5.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 OAG10484.1 - 2.9 7.4 10.0 9.2 5.7 9.8 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 OAG10484.1 - 3.7 8.2 15.3 2 9.1 12.2 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COesterase PF00135.28 OAG10485.1 - 9.9e-67 225.9 0.0 2.1e-66 224.9 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG10485.1 - 6.8e-07 29.4 0.1 4.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG10485.1 - 0.0011 18.5 0.2 0.0019 17.7 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3295 PF11702.8 OAG10487.1 - 7e-20 71.8 5.8 1.2e-19 71.1 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) TPR_14 PF13428.6 OAG10487.1 - 0.027 15.3 0.8 11 7.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG10487.1 - 0.093 13.0 0.1 0.33 11.3 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat UBA_4 PF14555.6 OAG10489.1 - 0.0061 16.4 0.0 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 UBA-like domain DUF1068 PF06364.12 OAG10489.1 - 0.07 13.0 0.3 0.092 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DAHP_synth_2 PF01474.16 OAG10490.1 - 1.8e-203 675.9 0.0 2.4e-203 675.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Zn_clus PF00172.18 OAG10492.1 - 9.3e-05 22.5 14.2 0.00015 21.8 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_11 PF14833.6 OAG10494.1 - 1.7e-26 92.9 0.0 2.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 OAG10494.1 - 0.057 13.6 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N_2 PF13602.6 OAG10495.1 - 4.9e-27 95.6 0.3 9.7e-27 94.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG10495.1 - 5.1e-18 65.3 1.3 1.3e-17 64.0 0.3 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG10495.1 - 2.9e-05 23.9 0.1 0.0014 18.5 0.0 2.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 OAG10495.1 - 0.0048 16.4 0.2 0.007 15.8 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme OPT PF03169.15 OAG10496.1 - 4.5e-128 428.6 47.8 5.1e-128 428.4 47.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 OAG10496.1 - 0.43 9.9 3.6 0.24 10.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Methyltransf_31 PF13847.6 OAG10497.1 - 4.5e-09 36.3 0.0 1.2e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG10497.1 - 1.1e-08 35.2 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG10497.1 - 2.6e-08 34.5 0.0 4.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG10497.1 - 9.7e-05 22.9 0.0 0.00018 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG10497.1 - 0.00015 22.5 0.0 0.00028 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG10497.1 - 0.0099 15.2 0.0 0.031 13.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family RSN1_7TM PF02714.15 OAG10498.1 - 4.8e-66 222.9 17.5 8.2e-66 222.1 17.5 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG10498.1 - 1.9e-40 138.2 0.9 4.5e-40 137.0 0.9 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG10498.1 - 2.5e-37 128.8 0.0 3.6e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Glyco_hydro_61 PF03443.14 OAG10499.1 - 0.0073 16.3 0.0 0.033 14.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 SKG6 PF08693.10 OAG10500.1 - 9.5e-09 34.5 0.4 2.8e-08 33.0 0.4 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 OAG10500.1 - 0.0015 18.4 1.1 0.0046 16.8 0.0 1.9 1 1 1 2 2 2 1 Transmembrane protein 51 Podoplanin PF05808.11 OAG10500.1 - 0.0017 18.5 0.6 0.0029 17.7 0.6 1.3 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.6 OAG10500.1 - 0.0028 17.7 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Mid2 PF04478.12 OAG10500.1 - 0.0044 16.9 5.2 0.011 15.6 0.0 2.3 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor CbtA PF09490.10 OAG10500.1 - 0.015 15.0 0.1 0.015 15.0 0.1 2.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Glycophorin_A PF01102.18 OAG10500.1 - 0.019 15.2 0.1 0.039 14.2 0.1 1.6 1 1 0 1 1 1 0 Glycophorin A DUF2207 PF09972.9 OAG10500.1 - 0.025 13.4 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Neurensin PF14927.6 OAG10500.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Neurensin TMEM154 PF15102.6 OAG10500.1 - 0.067 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF347 PF03988.12 OAG10500.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) MSA-2c PF12238.8 OAG10500.1 - 4.1 7.4 9.9 0.082 12.9 2.9 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Acetyltransf_10 PF13673.7 OAG10502.1 - 9.7e-10 38.5 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG10502.1 - 1.7e-07 31.5 0.0 2.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG10502.1 - 9.9e-07 28.6 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG10502.1 - 0.00065 20.1 0.0 0.0013 19.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG10502.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PAS_9 PF13426.7 OAG10503.1 - 8.1e-14 51.7 0.0 8.4e-12 45.3 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAG10503.1 - 0.0037 17.3 0.0 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAG10503.1 - 0.0043 17.3 0.1 16 5.8 0.0 3.6 3 0 0 3 3 3 2 PAS fold PQ-loop PF04193.14 OAG10504.1 - 5.1e-36 122.3 6.9 1.7e-18 66.1 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF4064 PF13273.6 OAG10504.1 - 0.035 14.4 0.0 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) ATP-sulfurylase PF01747.17 OAG10506.1 - 1.1e-87 292.9 0.0 1.6e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 OAG10506.1 - 5.3e-57 192.1 0.0 8.5e-57 191.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 OAG10506.1 - 4.7e-53 179.1 0.0 7.7e-53 178.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.19 OAG10507.1 - 4.9e-39 134.1 0.0 6.9e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family E3_UFM1_ligase PF09743.9 OAG10508.1 - 0.0015 18.2 0.6 0.0042 16.8 0.6 1.7 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Lant_dehydr_C PF14028.6 OAG10508.1 - 0.078 12.5 1.4 0.15 11.5 1.4 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Nuc_N PF14448.6 OAG10508.1 - 0.13 12.1 1.0 19 5.2 0.3 2.7 1 1 1 2 2 2 0 Nuclease N terminal DUF3306 PF11748.8 OAG10508.1 - 1.5 9.7 5.8 0.54 11.1 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Ribosomal_S14 PF00253.21 OAG10509.1 - 7e-21 73.7 0.9 1.4e-20 72.8 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Hypoth_Ymh PF09509.10 OAG10509.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) dsDNA_bind PF01984.20 OAG10511.1 - 2.3e-37 127.7 12.7 3.1e-37 127.2 12.7 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain cwf18 PF08315.12 OAG10511.1 - 0.013 16.2 1.3 0.016 15.9 1.3 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Fes1 PF08609.10 OAG10511.1 - 0.031 15.1 0.9 0.19 12.6 0.1 2.0 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 DUF4615 PF15393.6 OAG10511.1 - 0.074 13.6 1.2 0.088 13.4 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) CD99L2 PF12301.8 OAG10511.1 - 0.16 12.2 2.2 1.4 9.2 0.2 2.1 2 0 0 2 2 2 0 CD99 antigen like protein 2 Methyltrn_RNA_4 PF09936.9 OAG10512.1 - 0.13 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase SNARE PF05739.19 OAG10514.1 - 8.1e-09 35.3 2.8 8.4e-09 35.3 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 OAG10514.1 - 3.4e-08 32.5 0.7 1.6e-07 30.4 0.7 2.2 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 OAG10514.1 - 0.00055 19.7 0.2 0.00055 19.7 0.2 3.3 2 1 0 3 3 3 2 Syntaxin DUF16 PF01519.16 OAG10514.1 - 0.012 16.1 0.3 0.012 16.1 0.3 2.9 2 1 0 2 2 1 0 Protein of unknown function DUF16 KxDL PF10241.9 OAG10514.1 - 0.051 13.8 12.9 0.38 11.1 0.1 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein SlyX PF04102.12 OAG10514.1 - 0.078 13.6 0.1 0.078 13.6 0.1 3.5 3 1 0 3 3 3 0 SlyX Syntaxin-18_N PF10496.9 OAG10514.1 - 0.1 12.8 3.7 0.13 12.5 1.5 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF948 PF06103.11 OAG10514.1 - 0.16 12.3 1.3 2.5 8.4 0.0 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Siah-Interact_N PF09032.11 OAG10514.1 - 0.21 11.9 4.2 31 5.0 0.0 3.3 3 1 0 3 3 3 0 Siah interacting protein, N terminal DUF3829 PF12889.7 OAG10514.1 - 0.24 10.9 9.1 0.21 11.0 0.6 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3829) DUF1664 PF07889.12 OAG10514.1 - 1.7 8.7 10.2 2.4 8.2 0.1 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Alpha-2-MRAP_C PF06401.11 OAG10514.1 - 2.4 8.1 7.4 3.6 7.5 4.9 2.4 2 1 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Septin PF00735.18 OAG10516.1 - 9.1e-34 117.0 0.0 6.2e-19 68.4 0.0 3.0 2 1 0 2 2 2 2 Septin Dynamin_N PF00350.23 OAG10516.1 - 0.00052 20.1 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin family FtsK_SpoIIIE PF01580.18 OAG10516.1 - 0.0039 16.6 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 OAG10516.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG10516.1 - 0.1 13.0 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain YL1 PF05764.13 OAG10516.1 - 4.7 7.3 8.2 0.46 10.6 1.9 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Ank_4 PF13637.6 OAG10517.1 - 0.014 16.0 0.0 13 6.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Helo_like_N PF17111.5 OAG10518.1 - 0.00034 20.0 0.2 0.00042 19.7 0.2 1.0 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TF_AP-2 PF03299.14 OAG10518.1 - 0.015 15.3 0.2 0.08 12.9 0.2 1.9 2 0 0 2 2 2 0 Transcription factor AP-2 PspA_IM30 PF04012.12 OAG10518.1 - 0.098 12.2 2.0 0.3 10.7 0.1 2.1 1 1 1 2 2 2 0 PspA/IM30 family Prefoldin_2 PF01920.20 OAG10518.1 - 0.16 12.0 1.3 1.3 9.0 0.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF2076 PF09849.9 OAG10520.1 - 5.8e-07 29.8 15.0 9.2e-07 29.2 15.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 OAG10520.1 - 0.0011 19.1 1.9 0.0018 18.4 1.9 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 OAG10520.1 - 0.014 15.4 0.5 0.023 14.7 0.5 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Trypan_glycop_C PF10659.9 OAG10520.1 - 0.066 13.6 1.1 0.093 13.1 1.1 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain ApbA_C PF08546.11 OAG10521.1 - 2.1e-31 108.7 0.1 2.9e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG10521.1 - 9.1e-23 80.6 0.0 7.9e-22 77.5 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 OAG10522.1 - 1.1e-12 48.4 2.0 2.5e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family eIF-3c_N PF05470.12 OAG10522.1 - 1.1 7.5 16.8 1.6 7.0 16.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Hamartin PF04388.12 OAG10522.1 - 9.1 4.8 12.3 13 4.3 12.3 1.2 1 0 0 1 1 1 0 Hamartin protein Sec2p PF06428.11 OAG10523.1 - 1e-26 92.7 14.8 1e-26 92.7 14.8 3.5 3 1 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF445 PF04286.12 OAG10523.1 - 0.001 19.0 4.2 0.001 19.0 4.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF445) AAA_assoc PF14363.6 OAG10523.1 - 0.062 13.7 0.5 0.16 12.4 0.5 1.7 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA DUF3584 PF12128.8 OAG10523.1 - 0.071 10.6 22.1 0.14 9.7 22.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5339 PF17274.2 OAG10523.1 - 0.25 12.2 9.7 6.6 7.7 0.4 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DUF1664 PF07889.12 OAG10523.1 - 7.6 6.6 13.1 2.8 8.0 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fungal_trans PF04082.18 OAG10524.1 - 3.9e-13 49.0 0.1 5.3e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10524.1 - 1.9e-05 24.7 13.9 3.6e-05 23.8 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG10525.1 - 5e-43 147.4 47.7 5e-43 147.4 47.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Ras PF00071.22 OAG10528.1 - 6.7e-54 181.9 0.0 7.7e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG10528.1 - 1.4e-20 73.6 0.0 2.4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG10528.1 - 1.7e-07 30.9 0.0 2.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG10528.1 - 0.0036 16.9 0.0 0.0085 15.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain UBX PF00789.20 OAG10529.1 - 8.4e-09 35.5 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain DUF737 PF05300.11 OAG10529.1 - 0.0014 19.0 10.1 0.0026 18.2 10.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF737) PIEZO PF15917.5 OAG10529.1 - 0.69 9.3 4.1 1.2 8.6 4.1 1.3 1 0 0 1 1 1 0 Piezo Herpes_DNAp_acc PF04929.12 OAG10529.1 - 1.9 7.4 14.8 3.8 6.4 14.8 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF1840 PF08895.11 OAG10529.1 - 6 7.2 8.1 12 6.2 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) CMS1 PF14617.6 OAG10530.1 - 8.2e-66 221.9 4.8 1e-65 221.6 4.8 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 OAG10530.1 - 5.4e-05 23.0 0.2 0.0001 22.1 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase CDC45 PF02724.14 OAG10530.1 - 0.17 10.1 4.3 1.4 7.1 0.0 2.1 2 0 0 2 2 2 0 CDC45-like protein CENP-T_C PF15511.6 OAG10531.1 - 1.3e-42 144.3 1.1 2.6e-42 143.3 0.0 2.0 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAG10531.1 - 6.1e-08 32.9 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 OAG10531.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAG10531.1 - 0.023 15.0 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 OAG10531.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated SURF1 PF02104.15 OAG10532.1 - 1e-40 139.9 0.0 1.3e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family SPACA7 PF15307.6 OAG10534.1 - 0.074 13.3 0.6 0.074 13.3 0.6 2.2 2 1 0 2 2 2 0 Sperm acrosome-associated protein 7 Flavin_Reduct PF01613.18 OAG10536.1 - 3.1e-17 63.0 0.1 4.5e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.25 OAG10537.1 - 3e-17 62.7 0.0 1.8e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10537.1 - 9.5e-09 35.2 0.0 0.00046 19.8 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10537.1 - 0.022 14.7 0.5 0.064 13.2 0.0 2.0 2 1 0 2 2 2 0 KR domain Rhodanese PF00581.20 OAG10538.1 - 8.9e-19 68.0 0.0 1.1e-10 41.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain zf-ANAPC11 PF12861.7 OAG10539.1 - 3.2e-43 145.7 8.8 3.8e-43 145.5 8.8 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG10539.1 - 7.9e-23 80.5 11.3 1.2e-22 79.9 11.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG10539.1 - 1.1e-07 32.1 13.9 6.6e-07 29.6 13.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG10539.1 - 2.4e-06 27.3 10.4 5.6e-06 26.1 10.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG10539.1 - 1.8e-05 24.7 9.6 0.00039 20.4 6.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG10539.1 - 0.00031 20.6 13.1 0.0021 18.0 13.2 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG10539.1 - 0.00046 20.0 7.5 0.00046 20.0 7.5 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG10539.1 - 0.00065 19.5 11.2 0.0014 18.4 6.2 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG10539.1 - 0.0043 17.2 3.6 0.0043 17.2 3.6 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAG10539.1 - 0.013 15.3 11.8 0.46 10.3 9.1 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAG10539.1 - 0.015 14.9 6.6 0.015 14.9 6.6 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OAG10539.1 - 0.021 14.7 5.7 0.049 13.5 5.5 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.16 OAG10539.1 - 0.067 13.1 10.0 0.092 12.6 4.6 2.3 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 OAG10539.1 - 0.072 12.9 0.1 0.072 12.9 0.1 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.8 OAG10539.1 - 0.11 12.6 13.7 1.1 9.5 13.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 OAG10539.1 - 0.22 11.3 13.3 0.65 9.8 9.9 2.8 2 1 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 OAG10539.1 - 0.81 10.0 11.5 2.1 8.7 11.5 1.8 1 1 0 1 1 1 0 RING-like domain RecR PF02132.15 OAG10539.1 - 0.93 9.1 9.3 0.6 9.7 0.3 3.0 3 0 0 3 3 3 0 RecR protein RINGv PF12906.7 OAG10539.1 - 1.6 8.9 12.5 7.6 6.8 12.2 2.1 1 1 0 1 1 1 0 RING-variant domain DZR PF12773.7 OAG10539.1 - 1.7 8.7 13.3 9 6.4 6.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H_2 PF13832.6 OAG10539.1 - 2.7 8.2 9.7 0.59 10.3 4.4 2.0 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAG10539.1 - 7.6 6.9 11.5 4.1 7.7 6.6 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain Dioxygenase_C PF00775.21 OAG10541.1 - 4.8e-08 32.6 0.1 8.4e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase SpaA PF17802.1 OAG10541.1 - 0.068 13.5 0.2 0.32 11.4 0.2 2.1 1 1 0 1 1 1 0 Prealbumin-like fold domain DUF3506 PF12014.8 OAG10542.1 - 4.4e-52 175.8 0.0 9.1e-52 174.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 OAG10542.1 - 3.7e-06 26.7 0.1 7.7e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG10542.1 - 3.9e-05 23.5 0.1 8.6e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF1769 PF08588.10 OAG10543.1 - 5.8e-24 84.1 0.3 1.1e-23 83.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.20 OAG10544.1 - 4.5e-97 325.3 0.0 8.2e-97 324.5 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 OAG10545.1 - 0.028 13.4 15.9 0.047 12.6 15.9 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF202 PF02656.15 OAG10545.1 - 0.79 10.2 9.0 1.8 9.0 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) STIL_N PF15253.6 OAG10548.1 - 0.14 11.1 0.2 0.27 10.1 0.0 1.4 2 0 0 2 2 2 0 SCL-interrupting locus protein N-terminus FKBP_C PF00254.28 OAG10549.1 - 8.4e-32 109.4 0.0 1e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WD40 PF00400.32 OAG10550.1 - 2.3e-115 373.2 34.1 1.3e-10 41.6 0.3 12.9 13 0 0 13 13 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG10550.1 - 5.7e-39 132.3 3.9 0.0023 18.2 0.0 11.4 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG10550.1 - 9.9e-28 97.0 1.2 0.67 8.9 0.0 11.1 1 1 10 11 11 11 10 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 OAG10550.1 - 7.9e-19 67.0 0.0 13 5.6 0.0 11.4 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 OAG10550.1 - 8e-19 67.7 26.0 0.071 11.7 0.1 11.0 2 1 9 11 11 11 7 Nucleoporin Nup120/160 eIF2A PF08662.11 OAG10550.1 - 2e-13 50.7 0.0 0.059 13.2 0.0 5.7 1 1 5 7 7 7 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OAG10550.1 - 1.6e-12 47.0 0.5 26 4.9 0.0 10.0 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Stimulus_sens_1 PF13756.6 OAG10550.1 - 3.2e-11 43.8 0.5 21 5.7 0.0 9.9 11 0 0 11 11 9 0 Stimulus-sensing domain AAA_16 PF13191.6 OAG10550.1 - 3.3e-09 37.4 0.2 9.8e-09 35.8 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAG10550.1 - 9.3e-09 35.4 0.0 2.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Robl_LC7 PF03259.17 OAG10550.1 - 1.9e-08 34.0 4.7 22 4.9 0.0 9.0 10 1 1 11 11 10 0 Roadblock/LC7 domain SMP_2 PF10144.9 OAG10550.1 - 1.1e-05 25.2 0.0 46 3.6 0.0 7.4 5 2 4 9 9 9 0 Bacterial virulence factor haemolysin DUF3261 PF11659.8 OAG10550.1 - 1.2e-05 25.2 0.9 14 5.5 0.0 6.3 3 2 4 7 7 7 0 Protein of unknown function (DUF3261) IKI3 PF04762.12 OAG10550.1 - 4.1e-05 21.8 1.9 0.51 8.3 0.1 4.5 2 2 2 4 4 4 2 IKI3 family Defensin_RK-1 PF17860.1 OAG10550.1 - 7.5e-05 23.1 0.8 5.3e+02 1.2 0.0 8.7 10 0 0 10 10 10 0 RK-1-like defensin AAA_22 PF13401.6 OAG10550.1 - 0.0011 19.3 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG10550.1 - 0.0053 16.9 0.7 0.16 12.1 0.1 3.1 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OAG10550.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Coatomer_WDAD PF04053.14 OAG10550.1 - 0.012 14.7 0.0 35 3.3 0.0 4.9 1 1 5 7 7 7 0 Coatomer WD associated region KAP_NTPase PF07693.14 OAG10550.1 - 0.033 13.4 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 OAG10550.1 - 0.11 13.0 0.0 0.41 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OAG10550.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GSDH PF07995.11 OAG10550.1 - 0.19 11.0 0.0 14 4.9 0.0 3.8 3 2 2 5 5 5 0 Glucose / Sorbosone dehydrogenase PNP_UDP_1 PF01048.20 OAG10552.1 - 2.8e-06 26.8 2.5 2e-05 24.0 2.5 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.18 OAG10555.1 - 3.4e-20 72.2 0.1 5.1e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10556.1 - 3.8e-10 39.7 10.9 5.7e-10 39.1 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DFP PF04127.15 OAG10557.1 - 6.7e-14 52.1 0.0 1e-05 25.5 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Glyoxal_oxid_N PF07250.11 OAG10559.1 - 2e-40 138.5 0.1 2.7e-39 134.8 0.0 2.8 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 OAG10559.1 - 1.1e-23 83.3 0.1 2.4e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.19 OAG10559.1 - 1.1e-21 76.9 85.7 4.5e-08 33.4 23.5 4.2 4 0 0 4 4 4 3 Chitin recognition protein Glyco_hydro_114 PF03537.13 OAG10561.1 - 3.4e-74 249.1 5.0 4.8e-74 248.6 5.0 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 PPP4R2 PF09184.11 OAG10561.1 - 0.00093 18.9 9.0 0.0015 18.2 9.0 1.3 1 0 0 1 1 1 1 PPP4R2 FYDLN_acid PF09538.10 OAG10561.1 - 0.0012 19.5 16.5 0.0045 17.7 16.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 OAG10561.1 - 0.065 13.0 15.5 0.1 12.3 15.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 OAG10561.1 - 0.21 11.8 18.2 0.36 11.1 18.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 OAG10561.1 - 0.22 10.8 12.3 0.36 10.1 12.3 1.3 1 0 0 1 1 1 0 BUD22 ORC6 PF05460.13 OAG10561.1 - 0.74 9.0 3.5 1.1 8.4 3.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NOA36 PF06524.12 OAG10561.1 - 2.4 7.4 23.7 5.7 6.2 23.7 1.6 1 0 0 1 1 1 0 NOA36 protein Med13_C PF06333.12 OAG10561.1 - 3.8 6.7 4.9 5.6 6.1 4.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Astro_capsid_p PF12226.8 OAG10561.1 - 7.7 5.6 19.4 12 4.9 19.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Peptidase_S41 PF03572.18 OAG10562.1 - 8.6e-10 38.4 0.0 2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 AMP-binding PF00501.28 OAG10565.1 - 1.8e-78 264.0 0.0 2.3e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG10565.1 - 4.5e-16 59.6 0.1 1.2e-15 58.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zip PF02535.22 OAG10567.1 - 6e-69 232.8 8.0 6.8e-69 232.6 8.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Bac_rhodopsin PF01036.18 OAG10569.1 - 2.6e-48 164.6 18.7 3.1e-48 164.3 18.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein NPIP PF06409.11 OAG10569.1 - 0.088 11.9 0.2 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) DUF1772 PF08592.11 OAG10569.1 - 0.54 10.6 16.9 3.1 8.1 3.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4131 PF13567.6 OAG10569.1 - 1.1 8.8 7.5 2.5 7.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4064 PF13273.6 OAG10569.1 - 1.4 9.2 9.7 3.6 7.9 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) TMEM208_SND2 PF05620.11 OAG10569.1 - 2.3 8.0 8.4 0.28 11.0 1.1 2.7 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 MerC PF03203.14 OAG10569.1 - 2.6 8.5 12.4 5.1 7.6 6.7 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein DUF3810 PF12725.7 OAG10569.1 - 4 6.7 8.7 1.5 8.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF4381 PF14316.6 OAG10569.1 - 9.5 6.5 7.7 0.87 9.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) RPEL PF02755.15 OAG10570.1 - 8.7e-33 111.1 14.9 7.2e-11 41.4 0.1 3.7 3 0 0 3 3 3 3 RPEL repeat KID PF02524.14 OAG10570.1 - 0.028 14.4 0.2 73 4.2 0.0 4.2 3 1 1 4 4 4 0 KID repeat Rotamase_3 PF13616.6 OAG10570.1 - 0.21 12.2 0.2 2.3 8.8 0.0 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Sugar_tr PF00083.24 OAG10571.1 - 3.3e-114 382.2 21.6 3.8e-114 382.0 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10571.1 - 4.2e-16 58.8 43.1 2.4e-15 56.4 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2518 PF10726.9 OAG10571.1 - 1.5 8.5 4.0 13 5.4 0.4 2.6 2 0 0 2 2 2 0 Protein of function (DUF2518) DUF2264 PF10022.9 OAG10572.1 - 1.9e-139 464.7 3.1 2.3e-139 464.4 3.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) GST_C PF00043.25 OAG10573.1 - 5.4e-11 42.6 0.1 7.9e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG10573.1 - 4.7e-06 26.7 0.0 7.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG10573.1 - 9.4e-06 25.6 3.2 1.7e-05 24.7 3.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain IMS PF00817.20 OAG10575.1 - 4.9e-41 140.2 0.3 8e-41 139.5 0.3 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAG10575.1 - 7.8e-16 58.8 0.6 2.7e-15 57.1 0.0 2.1 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAG10575.1 - 0.00019 21.5 0.1 0.0008 19.6 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif Vps36-NZF-N PF16988.5 OAG10575.1 - 0.0086 15.4 0.7 0.32 10.4 0.0 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain SBP_bac_6 PF13343.6 OAG10575.1 - 0.025 14.0 0.0 0.08 12.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Cellulase PF00150.18 OAG10577.1 - 1.6e-47 162.3 0.0 4e-47 161.0 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 OAG10577.1 - 4.8e-12 45.6 13.7 4.8e-12 45.6 13.7 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain FAD_binding_4 PF01565.23 OAG10578.1 - 6e-14 52.0 0.0 1.2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.23 OAG10579.1 - 4.2e-17 62.2 0.0 6.7e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain RbsD_FucU PF05025.13 OAG10579.1 - 0.065 13.7 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 RbsD / FucU transport protein family adh_short PF00106.25 OAG10580.1 - 4.4e-05 23.0 0.0 7.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG10580.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Dmd PF17587.2 OAG10581.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Discriminator of mRNA degradation DUF3330 PF11809.8 OAG10581.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Isochorismatase PF00857.20 OAG10582.1 - 5e-13 49.6 0.0 1.1e-12 48.5 0.0 1.6 2 1 0 2 2 2 1 Isochorismatase family GBR_NSP5 PF17580.2 OAG10583.1 - 0.26 11.1 3.9 0.47 10.3 3.9 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 zf-RING_2 PF13639.6 OAG10584.1 - 1.5e-06 28.4 4.6 9.5e-05 22.7 2.1 2.2 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 OAG10584.1 - 5.8e-05 23.0 3.2 5.8e-05 23.0 3.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OAG10584.1 - 0.00025 20.8 7.0 0.0038 17.0 2.0 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAG10584.1 - 0.00039 20.2 0.6 0.0012 18.7 0.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG10584.1 - 0.0013 18.6 4.6 0.072 13.0 1.8 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG10584.1 - 0.0015 18.5 2.7 0.11 12.5 1.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAG10584.1 - 0.0092 16.0 3.9 0.34 11.0 4.2 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OAG10584.1 - 0.012 15.4 4.8 0.44 10.4 1.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG10584.1 - 0.018 15.2 4.4 0.15 12.2 0.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAG10584.1 - 0.02 15.2 9.6 0.15 12.4 9.6 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain Zn-C2H2_12 PF18112.1 OAG10584.1 - 0.14 12.7 4.7 3.2 8.3 0.0 2.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_4 PF14570.6 OAG10584.1 - 0.31 10.9 4.2 11 5.9 0.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OAG10585.1 - 1.4e-10 41.3 2.7 2.2e-10 40.7 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG10585.1 - 4.1e-08 33.4 0.6 8.8e-08 32.3 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAG10585.1 - 5.4e-08 32.6 1.2 8.1e-05 22.4 0.3 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG10585.1 - 2e-06 27.7 3.7 3.3e-06 27.0 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG10585.1 - 1.8e-05 24.5 4.2 2.9e-05 23.8 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG10585.1 - 2.1e-05 24.3 5.7 8.4e-05 22.3 5.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG10585.1 - 3.7e-05 23.6 1.0 5.8e-05 23.0 0.5 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG10585.1 - 6.9e-05 22.6 6.7 0.001 18.9 6.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG10585.1 - 0.00012 22.1 2.2 0.00023 21.1 2.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OAG10585.1 - 0.0049 16.7 0.7 0.037 13.8 1.0 2.2 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OAG10585.1 - 0.021 14.6 0.5 0.042 13.6 0.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-Di19 PF05605.12 OAG10585.1 - 0.026 14.8 1.0 9.2 6.6 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 OAG10585.1 - 0.043 13.7 2.3 0.078 12.9 2.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 OAG10585.1 - 0.047 13.5 7.2 0.32 10.8 7.8 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 OAG10585.1 - 0.37 11.1 3.2 0.81 10.0 3.2 1.7 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 OAG10585.1 - 0.65 10.2 3.9 2.2 8.5 1.0 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C2H2_4 PF13894.6 OAG10585.1 - 1.5 9.9 3.8 88 4.4 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 OAG10585.1 - 2.8 8.5 6.7 9.8 6.7 0.3 3.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain PD40 PF07676.12 OAG10588.1 - 0.025 14.5 0.5 0.14 12.1 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Lactonase PF10282.9 OAG10588.1 - 0.034 13.4 0.0 0.08 12.2 0.0 1.4 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller SGL PF08450.12 OAG10588.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.7 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region SLT PF01464.20 OAG10589.1 - 5.4e-05 22.8 0.1 0.00079 19.1 0.0 2.1 2 0 0 2 2 2 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 OAG10589.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Lysozyme-like FA_desaturase PF00487.24 OAG10590.1 - 3.8e-12 46.6 26.9 6.3e-12 45.9 26.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase RseC_MucC PF04246.12 OAG10590.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Zn_clus PF00172.18 OAG10591.1 - 2.1e-07 31.0 13.4 4.4e-07 29.9 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG10591.1 - 3.1e-06 26.4 0.1 4.7e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_5 PF14634.6 OAG10592.1 - 0.0052 16.7 6.4 0.012 15.6 0.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG10592.1 - 0.044 14.1 0.2 0.044 14.1 0.2 2.6 2 1 0 2 2 2 0 Ring finger domain MRP-63 PF14978.6 OAG10592.1 - 0.084 13.5 2.5 0.21 12.3 2.5 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 OEP PF02321.18 OAG10592.1 - 0.3 10.9 2.8 0.5 10.2 2.8 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein DZR PF12773.7 OAG10592.1 - 0.75 9.9 4.6 0.65 10.1 1.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OAG10593.1 - 0.82 9.2 5.9 9.6 5.8 1.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Mitofilin PF09731.9 OAG10595.1 - 2.6e-134 449.4 30.2 7e-115 385.2 34.1 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF4449 PF14613.6 OAG10595.1 - 0.11 12.6 12.3 0.36 10.9 11.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) Focal_AT PF03623.13 OAG10595.1 - 0.64 10.0 9.8 0.15 12.1 4.7 2.2 1 1 1 2 2 2 0 Focal adhesion targeting region DUF2780 PF11075.8 OAG10595.1 - 1.3 9.2 6.6 6.1 6.9 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) UPF0160 PF03690.13 OAG10595.1 - 2 7.9 10.3 3 7.4 10.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) ALMT PF11744.8 OAG10595.1 - 2.4 6.9 14.1 4.2 6.1 14.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Syja_N PF02383.18 OAG10597.1 - 6.6e-90 301.7 0.0 8.3e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain 7TMR-DISM_7TM PF07695.11 OAG10597.1 - 0.0053 16.7 2.5 0.0084 16.0 2.5 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF780 PF05611.11 OAG10597.1 - 0.04 14.7 2.1 0.09 13.5 2.1 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) T3SS_ATPase_C PF18269.1 OAG10597.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Ras PF00071.22 OAG10598.1 - 2e-58 196.6 0.1 2.3e-58 196.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG10598.1 - 3.3e-36 124.1 0.1 6.8e-36 123.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG10598.1 - 1.5e-14 53.9 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG10598.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG10598.1 - 3.6e-06 26.5 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAG10598.1 - 5.2e-06 26.1 0.0 7.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG10598.1 - 1.6e-05 24.9 0.6 0.13 12.2 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAG10598.1 - 0.0052 17.2 0.2 0.01 16.2 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG10598.1 - 0.033 14.5 0.0 2.5 8.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF4360 PF14273.6 OAG10602.1 - 7.4e-13 48.8 1.3 9.5e-13 48.4 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) p450 PF00067.22 OAG10603.1 - 1.3e-51 175.8 0.0 1.7e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1556 PF07590.11 OAG10603.1 - 0.19 12.1 0.1 2.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) p450 PF00067.22 OAG10604.1 - 2.9e-60 204.3 0.0 3.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF302 PF03625.14 OAG10605.1 - 0.00083 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 FA_desaturase PF00487.24 OAG10606.1 - 6.6e-23 81.8 19.5 1e-22 81.3 19.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_hydro_35 PF01301.19 OAG10607.1 - 1.2e-86 291.2 1.3 2e-86 290.5 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAG10607.1 - 2.5e-56 189.1 7.1 9.8e-34 116.4 0.0 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 OAG10607.1 - 2.1e-47 161.3 3.2 3.9e-47 160.4 3.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 OAG10607.1 - 1.1e-25 88.9 0.1 3e-25 87.6 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 OAG10607.1 - 0.0051 16.3 0.1 0.02 14.3 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) IreB PF06135.12 OAG10607.1 - 0.13 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 IreB regulatory phosphoprotein Na_Ca_ex PF01699.24 OAG10608.1 - 8.5e-24 84.2 28.5 4.7e-15 55.9 9.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pro-kuma_activ PF09286.11 OAG10609.1 - 2.1e-41 141.5 0.0 3.6e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG10609.1 - 2.9e-06 26.8 0.0 6.2e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Subtilase family ATG_C PF09333.11 OAG10610.1 - 0.19 12.1 7.1 0.53 10.7 2.1 2.8 1 1 2 3 3 3 0 Autophagy-related protein C terminal domain HET PF06985.11 OAG10611.1 - 4.1e-13 49.9 1.3 3.1e-09 37.3 0.2 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) PP-binding PF00550.25 OAG10611.1 - 4.2e-09 36.6 0.1 1.1e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site MFS_1 PF07690.16 OAG10613.1 - 1.6e-34 119.4 28.9 4.1e-25 88.5 13.2 2.7 2 2 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG10613.1 - 2.6e-12 46.3 7.7 2.6e-12 46.3 7.7 3.4 3 0 0 3 3 3 2 Sugar (and other) transporter MFA1_2 PF17317.2 OAG10613.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 Fungal_trans_2 PF11951.8 OAG10614.1 - 6.2e-37 127.3 0.0 9.7e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10614.1 - 3.6e-06 27.0 8.7 6.6e-06 26.2 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Goodbye PF17109.5 OAG10619.1 - 3.8e-22 79.0 0.0 9.4e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 OAG10619.1 - 5.5e-09 36.2 0.0 1.8e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG10619.1 - 4.2e-07 30.5 0.0 5e-06 27.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG10619.1 - 0.00074 19.8 0.0 0.0042 17.4 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 OAG10619.1 - 0.01 16.3 0.0 0.074 13.5 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_MalT PF17874.1 OAG10619.1 - 0.013 14.9 0.1 0.013 14.9 0.1 2.2 2 1 0 2 2 2 0 MalT-like TPR region TPR_1 PF00515.28 OAG10619.1 - 0.016 15.0 1.8 0.2 11.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG10619.1 - 0.018 15.8 18.1 0.77 10.7 1.5 6.4 4 1 2 6 6 6 0 Tetratricopeptide repeat RNA_helicase PF00910.22 OAG10619.1 - 0.028 14.8 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 OAG10619.1 - 0.038 14.3 0.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG10619.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TPR_17 PF13431.6 OAG10619.1 - 0.048 14.1 0.0 18 6.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_5 PF07728.14 OAG10619.1 - 0.058 13.4 0.0 0.76 9.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 OAG10619.1 - 0.059 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 OAG10619.1 - 0.095 13.3 0.0 0.32 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 OAG10619.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 OAG10619.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 OAG10619.1 - 0.16 11.4 0.0 0.46 9.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein TPR_19 PF14559.6 OAG10619.1 - 0.52 10.9 9.3 2.6 8.6 0.1 4.5 3 1 3 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG10619.1 - 0.63 10.8 8.5 1.7 9.4 0.0 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 OAG10620.1 - 3.3e-25 88.9 0.0 6.7e-25 87.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family ThiD2 PF17792.1 OAG10620.1 - 0.042 14.3 0.7 0.3 11.6 0.1 2.2 2 0 0 2 2 2 0 ThiD2 family NAD_binding_8 PF13450.6 OAG10621.1 - 9.5e-13 48.2 0.5 3.2e-12 46.5 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG10621.1 - 5.7e-07 29.1 0.1 2.1e-05 23.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG10621.1 - 1.2e-06 28.4 0.3 9.3e-06 25.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG10621.1 - 7.5e-06 26.4 0.1 0.066 13.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG10621.1 - 1.4e-05 24.4 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG10621.1 - 0.00014 20.7 0.1 0.0015 17.3 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 OAG10621.1 - 0.00051 20.1 0.3 0.0025 17.8 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG10621.1 - 0.00079 18.8 1.1 0.23 10.7 0.0 3.4 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG10621.1 - 0.00091 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG10621.1 - 0.0028 16.9 0.0 0.0084 15.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 OAG10621.1 - 0.0033 16.9 0.6 0.28 10.5 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG10621.1 - 0.021 14.1 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 OAG10621.1 - 0.07 12.8 0.1 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAG10621.1 - 0.16 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 OAG10621.1 - 0.17 11.1 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG10621.1 - 0.22 10.6 0.2 0.33 10.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_16 PF00722.21 OAG10622.1 - 1.1e-08 34.8 0.0 5.2e-08 32.6 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF4863 PF16155.5 OAG10623.1 - 4.8e-69 231.1 0.0 5.6e-69 230.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) WD40 PF00400.32 OAG10624.1 - 4e-25 87.6 9.1 0.00015 22.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG10624.1 - 3.3e-14 53.0 4.7 9.9e-05 22.6 0.2 4.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG10624.1 - 5.2e-07 29.7 0.6 0.015 15.2 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 OAG10624.1 - 0.028 13.0 0.0 0.056 12.0 0.0 1.4 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Ge1_WD40 PF16529.5 OAG10624.1 - 0.11 11.4 0.0 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M18 PF02127.15 OAG10625.1 - 3.2e-169 563.3 0.0 4e-169 563.0 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Hydrolase_6 PF13344.6 OAG10626.1 - 5.5e-30 103.5 0.0 9.3e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG10626.1 - 9.5e-14 51.2 0.0 2.4e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG10626.1 - 2.1e-10 41.2 0.2 9.3e-05 22.8 0.0 3.1 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG10626.1 - 1.3e-06 28.6 0.1 0.0052 16.9 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase DNA_primase_lrg PF04104.14 OAG10627.1 - 1.5e-84 283.6 0.0 2.6e-84 282.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit FAA_hydrolase PF01557.18 OAG10628.1 - 1.8e-57 194.5 0.0 2.2e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.11 OAG10629.1 - 2.5e-25 88.0 0.2 4.8e-17 61.4 0.2 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG10629.1 - 1.8e-05 24.7 1.0 0.00087 19.2 0.1 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG10629.1 - 0.00032 20.3 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) DMSP_lyase PF16867.5 OAG10629.1 - 0.015 14.9 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase EutQ PF06249.12 OAG10629.1 - 0.11 12.2 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ ARD PF03079.14 OAG10629.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family FAD_binding_3 PF01494.19 OAG10630.1 - 5.2e-17 62.1 0.1 2.4e-16 59.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG10630.1 - 5.5e-09 36.1 0.6 1.8e-08 34.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG10630.1 - 1e-08 35.2 4.8 0.0023 17.6 3.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG10630.1 - 7.8e-08 31.9 1.0 0.00063 19.1 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG10630.1 - 2.7e-06 26.7 2.8 4.4e-06 26.0 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG10630.1 - 9.3e-06 26.1 0.1 0.00016 22.2 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG10630.1 - 3.2e-05 22.8 0.6 0.00063 18.6 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG10630.1 - 0.00021 20.8 1.4 0.00033 20.1 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG10630.1 - 0.00028 20.1 0.9 0.002 17.2 1.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 OAG10630.1 - 0.00083 18.8 0.7 0.018 14.4 0.3 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAG10630.1 - 0.0013 17.7 2.6 0.11 11.3 0.4 2.9 2 1 1 3 3 3 1 Tryptophan halogenase GIDA PF01134.22 OAG10630.1 - 0.0065 15.6 2.4 0.015 14.4 2.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAG10630.1 - 0.053 12.8 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG10630.1 - 0.074 12.3 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG10630.1 - 0.091 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GPI2 PF06432.11 OAG10633.1 - 2e-122 408.0 0.7 2.4e-122 407.8 0.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase F-box-like_2 PF13013.6 OAG10634.1 - 0.071 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain Annexin PF00191.20 OAG10635.1 - 6e-22 77.5 3.8 1.6e-05 24.9 0.0 4.4 4 0 0 4 4 4 4 Annexin HET PF06985.11 OAG10636.1 - 3e-29 102.3 1.0 5e-29 101.5 1.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFA PF04828.14 OAG10638.1 - 8.1e-11 42.1 0.4 1.3e-10 41.5 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MoaE PF02391.17 OAG10639.1 - 1.1e-35 122.3 0.0 1.4e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 MoaE protein MFS_1 PF07690.16 OAG10642.1 - 5e-48 163.8 40.0 5e-48 163.8 40.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG10642.1 - 7.7e-11 41.5 9.2 7.7e-11 41.5 9.2 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAG10642.1 - 0.00094 17.6 3.0 0.00094 17.6 3.0 3.2 2 2 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family HET PF06985.11 OAG10643.1 - 2.2e-26 92.9 0.0 4.5e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 OAG10644.1 - 4.1e-67 226.6 0.0 6.1e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG10644.1 - 5.4e-13 49.7 0.3 1.4e-12 48.4 0.2 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 OAG10645.1 - 1e-28 99.4 2.5 1.2e-28 99.1 2.5 1.1 1 0 0 1 1 1 1 BolA-like protein Cofilin_ADF PF00241.20 OAG10645.1 - 0.051 13.4 0.0 0.091 12.6 0.0 1.5 1 1 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein AAA PF00004.29 OAG10646.1 - 9.5e-17 61.7 0.0 2.8e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TetR_C_9 PF14514.6 OAG10646.1 - 0.087 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 OAG10646.1 - 0.15 12.4 0.1 0.93 9.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain Gpr1_Fun34_YaaH PF01184.19 OAG10648.1 - 1.2e-88 296.2 18.7 1.4e-88 295.9 18.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cornichon PF03311.14 OAG10651.1 - 2.2e-50 170.1 12.3 2.5e-50 169.9 12.3 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 OAG10652.1 - 1.9e-28 98.1 5.6 2.4e-08 34.5 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG10652.1 - 6e-13 48.9 0.0 0.014 15.7 0.0 5.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG10652.1 - 1.6e-05 24.9 0.0 0.62 9.9 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OAG10652.1 - 0.012 14.7 0.0 0.066 12.3 0.0 2.0 3 0 0 3 3 3 0 Coatomer WD associated region Caps_synth PF05704.12 OAG10655.1 - 1.1e-11 44.7 0.3 2.4e-11 43.5 0.3 1.5 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 OAG10655.1 - 0.00021 21.8 0.0 0.00048 20.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif MFS_1 PF07690.16 OAG10656.1 - 1.4e-24 86.7 43.2 1.4e-13 50.5 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_25 PF13649.6 OAG10657.1 - 3.8e-09 37.1 0.0 7.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG10657.1 - 2.7e-06 27.9 0.0 5.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG10657.1 - 3.9e-06 26.7 0.0 4.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG10657.1 - 0.0012 19.5 0.0 0.0029 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG10657.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OAG10657.1 - 0.049 12.9 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG10657.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PAN_4 PF14295.6 OAG10658.1 - 0.0031 17.4 2.1 0.0064 16.4 2.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 OAG10658.1 - 0.062 13.1 2.6 0.13 12.1 2.6 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_2 PF08276.11 OAG10658.1 - 8.2 6.6 10.5 0.071 13.2 2.4 1.7 2 0 0 2 2 2 0 PAN-like domain zf-MYND PF01753.18 OAG10659.1 - 1.6e-09 37.6 12.8 1.6e-09 37.6 12.8 2.9 2 0 0 2 2 2 1 MYND finger zf-TFIIB PF13453.6 OAG10659.1 - 0.064 12.6 0.5 0.064 12.6 0.5 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger Cutinase PF01083.22 OAG10660.1 - 3e-42 144.6 0.6 4.2e-42 144.1 0.6 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG10660.1 - 4.5e-05 23.1 0.1 7.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_9 PF10081.9 OAG10660.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_2 PF02230.16 OAG10660.1 - 0.053 13.3 0.1 0.088 12.6 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VIT PF08487.10 OAG10661.1 - 5.7e-32 110.2 0.4 1.2e-31 109.2 0.4 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 OAG10661.1 - 1.4e-23 83.6 0.0 2.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 OAG10661.1 - 2.2e-15 56.3 0.1 7.4e-15 54.6 0.1 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OAG10661.1 - 3.8e-10 40.3 0.0 7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG10661.1 - 1.4e-07 32.1 0.0 5.1e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Ribosomal_60s PF00428.19 OAG10661.1 - 0.0014 19.2 3.5 0.0014 19.2 3.5 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein VWA_CoxE PF05762.14 OAG10661.1 - 0.0083 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Astro_capsid_p PF12226.8 OAG10661.1 - 0.25 10.4 1.8 0.31 10.2 0.4 1.8 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Peptidase_M20 PF01546.28 OAG10662.1 - 2.2e-30 105.9 0.0 2.9e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG10662.1 - 1.7e-13 50.5 0.0 4.7e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG10662.1 - 5.8e-07 29.4 0.0 4.8e-06 26.4 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M28 Ceramidase PF05875.12 OAG10665.1 - 1.3 8.4 9.5 0.68 9.3 3.3 2.1 2 0 0 2 2 2 0 Ceramidase DUF3433 PF11915.8 OAG10666.1 - 2.9e-31 107.8 19.4 1.4e-22 80.0 5.3 4.3 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Transgly_assoc PF04226.13 OAG10666.1 - 0.028 14.7 6.3 2.7 8.3 0.0 3.6 3 0 0 3 3 3 0 Transglycosylase associated protein Nnf1 PF03980.14 OAG10667.1 - 9.7e-27 93.5 1.6 9.7e-27 93.5 1.6 2.0 2 0 0 2 2 2 1 Nnf1 DUF892 PF05974.12 OAG10667.1 - 0.025 14.6 6.3 0.053 13.5 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Cytochrom_B562 PF07361.11 OAG10667.1 - 0.03 15.0 2.4 0.03 15.0 2.4 1.6 2 0 0 2 2 2 0 Cytochrome b562 Baculo_PEP_C PF04513.12 OAG10667.1 - 0.036 14.1 2.2 0.036 14.1 2.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1848 PF08902.11 OAG10667.1 - 0.052 13.3 0.3 0.44 10.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1848) RNase_H PF00075.24 OAG10667.1 - 0.42 10.8 2.3 0.69 10.1 0.4 2.0 2 0 0 2 2 2 0 RNase H ABC_tran_CTD PF16326.5 OAG10667.1 - 0.62 10.4 9.9 1.9 8.8 3.1 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Glyco_hydro_61 PF03443.14 OAG10669.1 - 3.9e-59 200.0 0.2 5.1e-59 199.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GST_N PF02798.20 OAG10670.1 - 9.9e-11 41.8 0.0 2.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG10670.1 - 5.7e-10 39.3 0.0 9.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG10670.1 - 5.1e-07 30.0 0.0 8.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG10670.1 - 6.7e-06 26.3 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG10670.1 - 9.4e-06 25.7 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG10670.1 - 3.2e-05 23.8 0.0 0.0001 22.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SET PF00856.28 OAG10671.1 - 8.8e-07 29.5 0.2 2.4e-05 24.8 0.1 2.6 1 1 1 2 2 2 2 SET domain zf-MYND PF01753.18 OAG10671.1 - 0.0016 18.5 6.9 0.0016 18.5 6.9 2.1 2 0 0 2 2 2 1 MYND finger zf-C2HCIx2C PF10782.9 OAG10671.1 - 0.51 10.3 2.5 1.4 8.9 1.9 2.1 2 1 0 2 2 2 0 Zinc-finger WD40 PF00400.32 OAG10672.1 - 7.9e-06 26.5 0.1 0.53 11.2 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG10672.1 - 3.1e-05 24.2 0.0 0.0078 16.5 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAG10672.1 - 0.016 15.2 0.2 0.048 13.6 0.1 1.9 2 0 0 2 2 2 0 LisH RRM_1 PF00076.22 OAG10673.1 - 8e-10 38.4 0.0 2.3e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribophorin_II PF05817.14 OAG10674.1 - 2.8e-34 118.7 0.0 3.2e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Pkinase PF00069.25 OAG10675.1 - 1.5e-29 103.1 0.0 2.2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG10675.1 - 8.5e-14 51.5 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG10675.1 - 0.0016 17.3 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAG10675.1 - 0.021 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAG10675.1 - 0.051 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3357 PF11837.8 OAG10676.1 - 0.00015 22.2 0.1 0.00052 20.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF997 PF06196.12 OAG10676.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) EGF_2 PF07974.13 OAG10676.1 - 2.2 8.7 10.5 4.7 7.7 10.5 1.6 1 0 0 1 1 1 0 EGF-like domain Abhydrolase_3 PF07859.13 OAG10679.1 - 3.1e-28 99.1 0.0 1.7e-24 86.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OAG10679.1 - 9.8e-08 31.3 0.1 1.4e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 OAG10679.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG10680.1 - 0.00012 21.4 0.0 0.0015 17.8 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG10680.1 - 0.00021 21.1 0.2 0.00037 20.2 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_trans_4_4 PF13579.6 OAG10680.1 - 0.054 13.9 3.8 0.14 12.6 0.0 2.9 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain Abhydrolase_3 PF07859.13 OAG10680.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2828 PF11443.8 OAG10681.1 - 4.3e-235 781.6 0.3 6.5e-235 781.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) RPN7 PF10602.9 OAG10682.1 - 5.4e-45 153.2 0.5 7.9e-45 152.7 0.5 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAG10682.1 - 1.2e-11 45.0 0.0 1.9e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 PCI domain Type2_restr_D3 PF16902.5 OAG10682.1 - 0.11 12.5 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Prp18 PF02840.15 OAG10682.1 - 0.13 12.3 0.7 0.59 10.2 0.4 2.0 2 0 0 2 2 2 0 Prp18 domain M PF02370.16 OAG10682.1 - 1.4 9.7 5.6 4.2 8.3 5.6 1.8 1 0 0 1 1 1 0 M protein repeat TPR_14 PF13428.6 OAG10682.1 - 3.9 8.6 8.3 10 7.3 0.0 4.5 4 2 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 OAG10683.1 - 6.8e-08 32.5 9.5 1.5e-07 31.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 OAG10685.1 - 0.0005 20.4 18.3 1.6 9.4 0.2 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.7 OAG10685.1 - 0.079 13.4 1.1 6.2 7.4 0.4 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG10685.1 - 0.11 13.4 15.6 1.6 9.8 0.1 5.1 4 1 0 4 4 4 0 C2H2-type zinc finger Pox_G9-A16 PF03003.16 OAG10685.1 - 0.18 11.6 0.1 0.34 10.6 0.1 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 zf-C2H2_jaz PF12171.8 OAG10685.1 - 0.57 10.5 4.9 12 6.3 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OAG10685.1 - 1.2 9.7 10.5 2.5 8.7 1.5 4.0 4 1 0 4 4 4 0 Zinc-finger double domain TRI12 PF06609.13 OAG10688.1 - 2.1e-68 231.2 25.9 2.7e-68 230.8 25.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG10688.1 - 3.4e-19 69.0 50.7 3.4e-19 69.0 50.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG10688.1 - 2.1e-12 46.7 8.4 2.1e-12 46.7 8.4 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 OAG10689.1 - 1.1e-75 254.6 0.0 1.2e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EthD PF07110.11 OAG10690.1 - 1.1e-15 58.6 0.1 1.3e-15 58.3 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG10690.1 - 3.8e-05 24.1 0.1 4.9e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase AtuA PF07287.11 OAG10691.1 - 5.3e-124 413.5 0.0 6.3e-124 413.2 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA p450 PF00067.22 OAG10692.1 - 1.3e-67 228.5 0.0 1.8e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_4 PF13669.6 OAG10693.1 - 5.4e-13 49.2 0.0 6.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 OAG10693.1 - 1.1e-12 48.2 0.0 2.2e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG10693.1 - 4.4e-08 33.9 0.1 1.3e-07 32.4 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG10693.1 - 0.00029 21.0 0.0 0.0017 18.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain adh_short PF00106.25 OAG10694.1 - 5.3e-44 150.0 0.6 6.6e-44 149.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10694.1 - 1.9e-29 102.9 0.2 2.5e-29 102.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10694.1 - 1.9e-13 50.8 0.4 2.5e-13 50.3 0.4 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG10694.1 - 0.0022 17.2 0.1 0.003 16.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GshA PF08886.11 OAG10694.1 - 0.11 11.0 0.0 0.51 8.8 0.0 1.8 2 0 0 2 2 2 0 Glutamate-cysteine ligase adh_short_C2 PF13561.6 OAG10695.1 - 2.8e-67 226.7 2.0 3.1e-67 226.6 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG10695.1 - 3e-51 173.7 2.6 3.5e-51 173.5 2.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG10695.1 - 3e-14 53.3 0.7 4.1e-14 52.9 0.7 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 OAG10695.1 - 0.0031 17.6 0.2 0.0061 16.6 0.2 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OAG10696.1 - 2e-20 73.1 0.4 3.7e-20 72.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG10696.1 - 2.5e-18 65.9 0.6 4.3e-18 65.2 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 OAG10696.1 - 4e-05 23.9 0.0 6.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 OAG10696.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG10696.1 - 0.00016 21.0 0.5 0.00035 19.9 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 OAG10696.1 - 0.0014 19.2 0.0 0.005 17.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 OAG10696.1 - 0.012 15.5 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 OAG10696.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase XdhC_C PF13478.6 OAG10696.1 - 0.022 15.3 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Methyltransf_11 PF08241.12 OAG10696.1 - 0.023 15.4 0.0 0.063 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 OAG10696.1 - 0.023 15.3 0.1 0.049 14.3 0.1 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Methyltransf_31 PF13847.6 OAG10696.1 - 0.082 12.7 0.2 0.19 11.5 0.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAG10696.1 - 0.15 11.4 0.1 0.24 10.7 0.1 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family UDPG_MGDP_dh_N PF03721.14 OAG10696.1 - 0.16 11.5 2.0 0.3 10.7 0.8 1.9 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.6 OAG10697.1 - 1.7e-27 96.5 0.0 4.6e-27 95.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG10697.1 - 1.5e-25 89.8 0.0 1.5e-24 86.6 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG10697.1 - 1.1e-08 35.2 0.2 2.4e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG10697.1 - 0.019 14.1 0.2 0.038 13.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RsdA_SigD_bd PF16751.5 OAG10697.1 - 0.083 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region NLPC_P60 PF00877.19 OAG10698.1 - 1.1e-11 44.7 0.1 2.4e-11 43.6 0.1 1.5 2 0 0 2 2 2 1 NlpC/P60 family UvrD-helicase PF00580.21 OAG10699.1 - 6.1e-63 213.2 2.9 5.6e-61 206.8 1.2 3.0 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OAG10699.1 - 2.1e-54 185.2 0.2 1.2e-53 182.8 0.0 2.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OAG10699.1 - 2e-34 119.0 0.3 2.9e-32 112.0 0.0 3.2 4 0 0 4 4 4 1 AAA domain UvrD_C_2 PF13538.6 OAG10699.1 - 4.5e-13 48.8 0.0 1.2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 OAG10699.1 - 1.2e-08 34.9 0.1 7.7e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 OAG10699.1 - 5.3e-05 23.1 0.0 0.31 10.7 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 OAG10699.1 - 0.00071 19.4 1.2 0.0027 17.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG10699.1 - 0.0032 17.7 2.1 16 5.8 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_12 PF13087.6 OAG10699.1 - 0.016 14.8 0.0 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain CDC27 PF09507.10 OAG10699.1 - 0.84 9.0 5.9 0.39 10.1 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 ANTH PF07651.16 OAG10700.1 - 6.2e-63 212.4 0.3 8.5e-63 211.9 0.3 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OAG10700.1 - 9.2e-07 28.9 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain CS PF04969.16 OAG10701.1 - 1.6e-16 61.0 0.1 3.3e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 CS domain PET122 PF05476.11 OAG10701.1 - 0.084 12.2 0.3 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 PET122 HET PF06985.11 OAG10703.1 - 2.9e-21 76.3 0.0 7.8e-21 75.0 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 OAG10704.1 - 2.1e-10 40.4 0.0 7.2e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG10704.1 - 1.1e-06 28.1 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.22 OAG10705.1 - 3.2e-21 75.9 0.0 4.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Ribosomal_L20 PF00453.18 OAG10707.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 Fer2_3 PF13085.6 OAG10708.1 - 0.00059 19.8 2.6 0.00098 19.1 2.6 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain C6_DPF PF10170.9 OAG10708.1 - 0.71 10.3 7.3 1.4 9.4 7.3 1.3 1 0 0 1 1 1 0 Cysteine-rich domain zf-B_box PF00643.24 OAG10708.1 - 5.9 7.1 12.0 2 8.7 4.8 2.5 2 1 0 2 2 2 0 B-box zinc finger Memo PF01875.17 OAG10709.1 - 3.6e-72 242.8 0.0 4.7e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Cad PF03596.13 OAG10710.1 - 4.5e-27 95.2 0.4 6.9e-27 94.6 0.4 1.2 1 0 0 1 1 1 1 Cadmium resistance transporter DUF4064 PF13273.6 OAG10710.1 - 0.37 11.1 6.3 0.68 10.2 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) AMP-binding PF00501.28 OAG10711.1 - 1.7e-56 191.7 0.0 2.4e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG10711.1 - 2.4e-10 41.2 0.1 5.5e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Prominin PF05478.11 OAG10712.1 - 0.065 11.2 0.2 0.077 10.9 0.2 1.0 1 0 0 1 1 1 0 Prominin DJ-1_PfpI PF01965.24 OAG10713.1 - 1.5e-13 50.9 0.0 2.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG10713.1 - 1.2e-05 25.1 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like E1-E2_ATPase PF00122.20 OAG10714.1 - 8.6e-42 142.7 5.9 1.5e-40 138.7 0.2 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG10714.1 - 2.4e-38 131.7 5.6 2.4e-38 131.7 5.6 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG10714.1 - 2.7e-22 80.1 0.1 1.4e-19 71.2 0.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG10714.1 - 4.3e-18 65.2 0.0 9.2e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG10714.1 - 5e-12 45.3 0.0 1.5e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG10714.1 - 3.7e-05 23.6 0.3 8.3e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 OAG10714.1 - 0.00054 19.8 5.5 0.005 16.6 0.1 3.4 3 1 0 3 3 3 1 Predicted membrane protein (DUF2157) HAD PF12710.7 OAG10714.1 - 0.044 14.2 0.0 0.55 10.6 0.0 2.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1996 PF09362.10 OAG10716.1 - 4.6e-71 239.5 3.4 6e-71 239.1 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CDH-cyt PF16010.5 OAG10717.1 - 7.1e-50 169.2 6.3 8.1e-50 169.0 6.3 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 OAG10717.1 - 0.0069 16.6 0.1 0.017 15.4 0.1 1.7 1 1 1 2 2 2 1 DOMON domain Spt5-NGN PF03439.13 OAG10719.1 - 5.5e-20 71.1 0.0 1.1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 OAG10719.1 - 7.9e-13 49.2 20.3 7.9e-13 49.2 20.3 2.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 OAG10719.1 - 3.7e-09 36.2 16.4 0.01 15.8 0.1 6.7 7 0 0 7 7 7 3 KOW motif CTD PF12815.7 OAG10719.1 - 2.3e-05 24.9 57.6 0.02 15.5 6.7 4.3 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 OAG10719.1 - 0.0004 20.6 2.0 0.0023 18.1 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) DUF1506 PF07405.11 OAG10719.1 - 0.0094 16.1 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1506) DUF3253 PF11625.8 OAG10719.1 - 0.14 12.4 1.3 0.44 10.8 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Hid1 PF12722.7 OAG10719.1 - 7.6 4.5 6.5 10 4.1 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein F-box PF00646.33 OAG10720.1 - 0.0048 16.8 0.6 0.093 12.6 0.5 2.8 2 0 0 2 2 2 1 F-box domain GAPES3 PF17154.4 OAG10720.1 - 0.0098 15.9 0.1 0.028 14.4 0.0 1.7 2 0 0 2 2 2 1 Gammaproteobacterial periplasmic sensor domain DUF2442 PF10387.9 OAG10720.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) CTP_transf_like PF01467.26 OAG10721.1 - 0.00025 21.3 0.3 0.0012 19.1 0.3 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like WD40 PF00400.32 OAG10722.1 - 1e-11 45.2 4.3 0.00012 22.8 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Carb_anhydrase PF00194.21 OAG10723.1 - 1.9e-32 112.8 0.0 2.9e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Metallophos PF00149.28 OAG10725.1 - 3.6e-35 122.3 0.1 5.5e-35 121.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG10725.1 - 1.4e-17 63.9 0.0 2.6e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Aldedh PF00171.22 OAG10726.1 - 3.7e-185 615.8 0.3 4.2e-185 615.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG10726.1 - 0.15 11.5 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Methyltransf_PK PF05891.12 OAG10727.1 - 1.5e-75 253.5 0.0 1.7e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OAG10727.1 - 0.0027 18.4 0.0 0.011 16.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Med8 PF10232.9 OAG10728.1 - 4.1e-10 39.6 4.8 5.6e-07 29.4 0.2 2.0 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 F-box PF00646.33 OAG10729.1 - 0.021 14.7 1.8 0.17 11.8 0.0 2.4 2 1 0 2 2 2 0 F-box domain LigD_N PF13298.6 OAG10731.1 - 8.4e-33 112.8 0.0 1.7e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Fringe PF02434.16 OAG10732.1 - 7.1e-08 32.2 0.2 4.9e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 OAG10732.1 - 0.0038 17.1 0.6 0.0092 15.9 0.6 1.6 1 0 0 1 1 1 1 PAN domain AMP-binding PF00501.28 OAG10733.1 - 7.6e-68 229.0 0.0 9.6e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG10733.1 - 2.2e-10 41.4 2.8 1.2e-09 39.1 0.3 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AtuA PF07287.11 OAG10734.1 - 1.4e-128 428.5 0.4 1.8e-128 428.2 0.4 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MaoC_dehydratas PF01575.19 OAG10735.1 - 5.4e-23 80.9 0.0 9.1e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAG10735.1 - 0.0002 21.5 0.0 0.052 13.7 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase ECH_1 PF00378.20 OAG10736.1 - 1.7e-59 201.2 0.0 2.2e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG10736.1 - 1.8e-24 86.8 0.0 7.6e-24 84.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OAG10737.1 - 1.5e-46 158.8 0.0 1.8e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG10737.1 - 3.5e-20 72.8 0.1 3.7e-18 66.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Plectin PF00681.20 OAG10737.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Plectin repeat TRI12 PF06609.13 OAG10738.1 - 2.9e-80 270.4 21.9 3.8e-80 270.0 21.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG10738.1 - 8.4e-29 100.6 49.0 1.2e-26 93.4 44.3 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG10738.1 - 3.7e-08 32.6 5.8 3.7e-08 32.6 5.8 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter AMP-binding PF00501.28 OAG10739.1 - 1.6e-79 267.5 0.1 2.1e-79 267.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG10739.1 - 4e-13 50.1 0.2 8.6e-13 49.1 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABM PF03992.16 OAG10740.1 - 0.00012 22.1 0.5 0.0065 16.6 0.1 2.5 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AtuA PF07287.11 OAG10741.1 - 4e-124 413.9 2.3 4.8e-124 413.6 2.3 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF3425 PF11905.8 OAG10742.1 - 9.7e-16 57.9 0.6 2.2e-15 56.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Spc29 PF17082.5 OAG10742.1 - 0.019 14.8 0.2 0.049 13.5 0.2 1.6 1 0 0 1 1 1 0 Spindle Pole Component 29 bZIP_1 PF00170.21 OAG10742.1 - 0.051 13.7 9.2 0.24 11.5 9.1 2.1 1 1 0 1 1 1 0 bZIP transcription factor Fungal_TACC PF12709.7 OAG10742.1 - 0.053 14.0 2.9 0.17 12.4 2.8 1.9 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3145 PF11343.8 OAG10742.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3145) YabA PF06156.13 OAG10742.1 - 0.15 12.7 0.9 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 Initiation control protein YabA MFS_1 PF07690.16 OAG10743.1 - 1.5e-31 109.7 30.3 1.9e-31 109.3 30.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FYVE PF01363.21 OAG10745.1 - 0.009 16.1 1.2 0.016 15.3 1.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 OAG10745.1 - 0.18 11.7 4.3 0.29 11.0 4.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.25 OAG10747.1 - 7.3e-37 126.7 0.2 9.7e-37 126.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10747.1 - 3.9e-32 111.7 0.3 5.5e-32 111.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10747.1 - 0.00012 22.0 1.5 0.0021 18.0 0.6 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG10747.1 - 0.00062 19.3 0.1 0.0012 18.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG10747.1 - 0.0089 15.1 0.1 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.15 OAG10747.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 OAG10747.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NIF3 PF01784.18 OAG10748.1 - 3.3e-12 46.6 0.0 7e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) SBF_like PF13593.6 OAG10750.1 - 1.8e-93 313.3 22.9 2e-93 313.1 22.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) 5-FTHF_cyc-lig PF01812.20 OAG10751.1 - 8.8e-11 42.0 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Cyt-b5 PF00173.28 OAG10752.1 - 7.1e-15 54.9 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HET PF06985.11 OAG10753.1 - 7.1e-13 49.1 5.2 3.2e-10 40.5 0.4 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 OAG10753.1 - 1.2e-08 35.0 0.2 2.4e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 OAG10753.1 - 1.2e-05 25.8 0.1 3.3e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_16 PF13191.6 OAG10753.1 - 0.0024 18.3 0.0 0.0071 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ank_3 PF13606.6 OAG10753.1 - 0.011 16.2 0.1 7.9 7.4 0.1 3.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 OAG10753.1 - 0.014 16.0 0.1 0.29 11.8 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) AAA_14 PF13173.6 OAG10753.1 - 0.021 14.8 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OAG10753.1 - 0.04 14.3 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG10753.1 - 0.044 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OAG10753.1 - 0.081 13.1 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG10753.1 - 0.097 12.9 0.0 0.4 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Ank PF00023.30 OAG10753.1 - 0.15 12.5 0.2 28 5.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 OAG10754.1 - 5.6e-12 45.9 0.1 9.3e-07 29.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG10754.1 - 1.1e-11 44.6 1.6 0.00021 21.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OAG10754.1 - 3.5e-11 43.5 0.4 9.1e-11 42.2 0.4 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG10754.1 - 1.6e-09 37.8 0.4 0.00058 20.1 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG10754.1 - 6.5e-09 35.3 0.1 0.019 15.4 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat RP-C_C PF11800.8 OAG10754.1 - 0.066 13.3 0.7 0.067 13.3 0.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region NAPRTase PF04095.16 OAG10755.1 - 8.3e-57 192.6 0.3 1.1e-29 103.7 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 OAG10755.1 - 1.3e-34 119.3 0.1 2.2e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Syntaxin PF00804.25 OAG10756.1 - 1.1e-20 74.1 14.5 3.2e-20 72.7 14.5 1.7 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 OAG10756.1 - 3.5e-10 39.7 3.6 3.5e-10 39.7 3.6 2.8 2 1 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 OAG10756.1 - 0.00041 20.7 10.5 0.0044 17.4 1.5 2.5 2 1 1 3 3 3 2 Syntaxin-like protein LMBR1 PF04791.16 OAG10756.1 - 0.011 14.6 4.5 0.019 13.9 4.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Vac_Fusion PF02346.16 OAG10756.1 - 0.019 14.6 3.2 15 5.3 0.2 3.4 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 RPW8 PF05659.11 OAG10756.1 - 0.024 14.3 3.0 0.18 11.5 0.3 2.4 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF5344 PF17279.2 OAG10756.1 - 0.028 15.0 9.4 1.4 9.5 0.3 3.4 2 1 0 3 3 3 0 Family of unknown function (DUF5344) UPF0184 PF03670.13 OAG10756.1 - 0.041 14.3 7.8 0.087 13.2 0.1 3.5 2 1 3 5 5 5 0 Uncharacterised protein family (UPF0184) Syntaxin-6_N PF09177.11 OAG10756.1 - 0.13 12.8 10.0 0.34 11.5 0.0 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.9 OAG10756.1 - 0.13 12.6 10.7 0.13 12.5 1.6 3.4 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 OAG10756.1 - 0.17 12.0 11.2 2 8.4 2.3 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCU PF04678.13 OAG10756.1 - 0.18 11.9 10.5 0.096 12.8 1.7 2.8 1 1 2 3 3 3 0 Mitochondrial calcium uniporter XhlA PF10779.9 OAG10756.1 - 0.2 11.9 0.1 0.2 11.9 0.1 4.1 3 1 0 3 3 2 0 Haemolysin XhlA NPV_P10 PF05531.12 OAG10756.1 - 0.28 11.7 11.6 5.7 7.5 1.3 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 OAG10756.1 - 0.4 11.2 13.5 2.6 8.6 0.1 3.8 2 1 1 3 3 3 0 Spectrin repeat GPS2_interact PF15784.5 OAG10756.1 - 0.47 10.9 11.9 4.7 7.7 1.5 3.2 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF2408 PF10303.9 OAG10756.1 - 0.71 10.4 11.8 89 3.6 11.8 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Tweety PF04906.13 OAG10756.1 - 0.99 8.0 10.0 0.17 10.5 2.5 2.3 1 1 0 2 2 2 0 Tweety DUF745 PF05335.13 OAG10756.1 - 1 9.1 16.8 0.4 10.4 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Mobilization_B PF17511.2 OAG10756.1 - 1.1 9.6 8.0 0.23 11.8 2.6 2.5 2 1 0 2 2 2 0 Mobilization protein B DUF1664 PF07889.12 OAG10756.1 - 1.1 9.3 10.8 3 7.9 1.4 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 OAG10756.1 - 1.4 8.8 9.0 27 4.6 0.0 3.0 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Pilin_N PF07790.11 OAG10756.1 - 2.3 9.2 6.1 6.5 7.8 6.1 1.8 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Spc7 PF08317.11 OAG10756.1 - 2.4 7.0 15.0 0.39 9.6 2.5 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein zf-CpG_bind_C PF12269.8 OAG10756.1 - 2.7 7.7 14.3 3.8 7.2 0.9 3.0 1 1 2 3 3 3 0 CpG binding protein zinc finger C terminal domain DUF4094 PF13334.6 OAG10756.1 - 4 7.9 12.1 0.89 10.0 2.2 3.1 3 1 0 3 3 2 0 Domain of unknown function (DUF4094) COG2 PF06148.11 OAG10756.1 - 4.7 7.3 8.3 2.8 8.0 0.4 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2203 PF09969.9 OAG10756.1 - 5 7.9 16.1 1.6 9.4 2.4 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DHR10 PF18595.1 OAG10756.1 - 6.6 6.8 16.6 0.41 10.7 4.5 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Tropomyosin_1 PF12718.7 OAG10756.1 - 7.7 6.7 16.8 11 6.1 4.1 3.1 2 1 0 3 3 3 0 Tropomyosin like Acetyltransf_19 PF18015.1 OAG10757.1 - 0.074 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Alginate_lyase PF05426.12 OAG10758.1 - 1.7e-19 70.4 0.0 3e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 Alginate lyase MFS_1 PF07690.16 OAG10759.1 - 1.2e-33 116.6 20.0 1.9e-33 115.8 20.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG10759.1 - 2.2e-05 23.9 2.6 2.2e-05 23.9 2.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4064 PF13273.6 OAG10759.1 - 9.9 6.5 16.9 0.12 12.7 5.9 3.3 3 2 1 4 4 4 0 Protein of unknown function (DUF4064) Glyco_hydro_88 PF07470.13 OAG10760.1 - 8e-20 71.2 4.9 1.2e-19 70.6 4.9 1.4 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 OAG10760.1 - 0.0089 15.5 0.1 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Fungal_trans PF04082.18 OAG10761.1 - 3.5e-19 68.9 0.0 6.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10761.1 - 1.2e-08 35.0 13.7 2.8e-08 33.7 13.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 OAG10761.1 - 3.3 8.3 11.9 1.8 9.1 8.3 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Glyco_hydro_28 PF00295.17 OAG10762.1 - 4.6e-15 55.5 0.1 6.7e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 OAG10762.1 - 0.0021 17.9 7.5 0.0037 17.1 0.7 2.9 2 1 1 3 3 3 1 Right handed beta helix region HET PF06985.11 OAG10764.1 - 2.7e-22 79.7 3.6 8.5e-22 78.1 3.6 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Xrn1_D3 PF18194.1 OAG10764.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 HET PF06985.11 OAG10765.1 - 4e-12 46.7 9.1 1.2e-10 41.9 0.9 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Calici_MSP PF05752.11 OAG10765.1 - 0.21 11.4 0.1 43 3.9 0.0 3.0 3 0 0 3 3 3 0 Calicivirus minor structural protein E1-E2_ATPase PF00122.20 OAG10768.1 - 6.5e-50 169.2 4.2 6.5e-50 169.2 4.2 2.3 1 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG10768.1 - 9.3e-21 75.1 0.0 1.5e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG10768.1 - 3.3e-07 30.7 0.2 1.4e-06 28.6 0.2 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 OAG10768.1 - 3.1e-05 23.9 0.5 0.00078 19.3 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 OAG10768.1 - 0.022 13.6 0.0 0.022 13.6 0.0 1.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MauE PF07291.11 OAG10768.1 - 0.68 9.7 10.8 0.42 10.4 3.7 2.8 2 1 0 2 2 2 0 Methylamine utilisation protein MauE Aldo_ket_red PF00248.21 OAG10769.1 - 2.7e-70 236.9 0.0 3.3e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 OAG10770.1 - 8.8e-26 90.7 17.1 1.4e-25 90.0 17.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2104 PF09877.9 OAG10770.1 - 0.0071 16.6 3.2 0.018 15.3 0.4 2.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2104) Ni_hydr_CYTB PF01292.20 OAG10770.1 - 0.079 12.6 8.7 1 8.9 2.7 2.6 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 TauD PF02668.16 OAG10771.1 - 3.9e-53 181.0 0.0 5e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PTR2 PF00854.21 OAG10772.1 - 5.8e-79 265.7 9.6 7.5e-79 265.4 9.6 1.1 1 0 0 1 1 1 1 POT family Sugar_tr PF00083.24 OAG10772.1 - 0.00045 19.2 1.0 0.00045 19.2 1.0 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10773.1 - 0.00011 21.2 6.7 0.00011 21.2 6.7 3.9 2 1 0 4 4 4 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG10773.1 - 0.0016 17.0 2.3 0.0016 17.0 2.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4235 PF14019.6 OAG10773.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DAO PF01266.24 OAG10774.1 - 1.7e-65 222.0 0.3 1.9e-65 221.8 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG10774.1 - 5.2e-07 29.2 0.1 0.0062 15.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG10774.1 - 1.5e-05 25.1 0.7 3.3e-05 24.0 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG10774.1 - 5.5e-05 22.2 0.2 0.0067 15.3 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 OAG10774.1 - 0.0006 20.3 0.2 0.12 13.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG10774.1 - 0.0016 18.4 0.2 0.7 9.9 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding MCRA PF06100.11 OAG10774.1 - 0.01 14.7 0.9 0.023 13.5 0.3 1.7 2 0 0 2 2 2 0 MCRA family GIDA PF01134.22 OAG10774.1 - 0.012 14.7 0.1 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 OAG10774.1 - 0.012 15.8 0.3 0.048 13.9 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 OAG10774.1 - 0.017 14.2 0.3 1.8 7.5 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 OAG10774.1 - 0.021 14.1 0.0 5.2 6.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Ldh_1_N PF00056.23 OAG10774.1 - 0.066 13.3 0.3 12 6.0 0.1 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Mqo PF06039.15 OAG10774.1 - 0.17 10.4 0.0 6.7 5.1 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) WW PF00397.26 OAG10775.1 - 1.1e-07 31.8 2.6 2.1e-07 30.9 2.6 1.5 1 0 0 1 1 1 1 WW domain EF-hand_4 PF12763.7 OAG10776.1 - 2.5e-35 120.6 0.0 3.7e-14 52.5 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 OAG10776.1 - 1.7e-09 38.0 0.0 0.0001 22.6 0.0 4.2 4 1 0 4 4 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG10776.1 - 2.1e-07 30.0 0.0 0.97 9.1 0.0 5.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 OAG10776.1 - 1.4e-06 27.7 0.3 2.7 8.2 0.1 6.1 6 0 0 6 6 6 1 EF-hand domain DUF812 PF05667.11 OAG10776.1 - 0.00032 19.7 15.6 0.00056 18.9 15.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) EF-hand_8 PF13833.6 OAG10776.1 - 0.0011 18.7 0.0 37 4.3 0.0 5.1 5 0 0 5 5 5 0 EF-hand domain pair Tup_N PF08581.10 OAG10776.1 - 0.0012 19.1 19.4 0.0012 19.1 5.7 3.2 2 1 1 3 3 3 2 Tup N-terminal Spc7 PF08317.11 OAG10776.1 - 0.0037 16.2 32.8 0.0098 14.8 17.4 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein GOLGA2L5 PF15070.6 OAG10776.1 - 0.027 13.1 17.6 0.046 12.4 17.6 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Filament PF00038.21 OAG10776.1 - 0.059 12.9 30.9 0.15 11.6 17.8 2.1 1 1 1 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 OAG10776.1 - 0.062 13.4 32.4 0.18 11.9 16.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.19 OAG10776.1 - 0.074 10.8 27.2 0.1 10.4 27.2 1.0 1 0 0 1 1 1 0 Myosin tail ATG16 PF08614.11 OAG10776.1 - 0.1 12.8 35.2 0.11 12.7 25.2 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 OAG10776.1 - 0.11 11.8 33.1 0.34 10.2 17.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding p31comet PF06581.12 OAG10776.1 - 0.21 10.7 0.6 0.39 9.8 0.6 1.3 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Fib_alpha PF08702.10 OAG10776.1 - 0.23 11.6 22.3 0.031 14.5 10.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.13 OAG10776.1 - 0.48 10.2 12.0 0.039 13.8 4.6 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region Fez1 PF06818.15 OAG10776.1 - 1.3 9.5 28.8 10 6.5 29.1 2.0 1 1 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 OAG10776.1 - 1.5 9.8 29.8 0.17 12.8 10.5 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 OAG10776.1 - 2.5 8.6 31.8 0.88 10.1 14.2 2.6 1 1 2 3 3 3 0 Apg6 coiled-coil region MscS_porin PF12795.7 OAG10776.1 - 2.7 7.5 35.3 4.5 6.7 14.4 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF724 PF05266.14 OAG10776.1 - 2.7 7.8 27.1 0.093 12.5 10.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) TMF_TATA_bd PF12325.8 OAG10776.1 - 3.5 7.9 27.5 0.56 10.4 7.0 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 OAG10776.1 - 4 6.2 29.6 0.68 8.7 17.0 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 OAG10776.1 - 4.1 6.8 30.1 7.2 6.0 14.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 ADIP PF11559.8 OAG10776.1 - 4.4 7.4 35.1 0.78 9.8 8.0 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 OAG10776.1 - 5 6.7 35.5 2.9 7.5 14.7 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 OAG10776.1 - 5.4 7.1 16.6 1.7 8.7 7.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 OAG10776.1 - 7.6 5.0 25.5 0.15 10.6 18.4 1.8 2 0 0 2 2 2 0 Macoilin family CCDC144C PF14915.6 OAG10776.1 - 8.3 5.4 32.3 1.3 8.1 12.5 2.1 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.9 OAG10776.1 - 8.9 6.3 29.6 6.3 6.8 15.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MMU163 PF17119.5 OAG10777.1 - 5.1e-84 281.3 7.7 7.1e-60 202.2 1.2 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Epimerase PF01370.21 OAG10778.1 - 3.3e-20 72.6 0.0 2.8e-19 69.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG10778.1 - 6.5e-12 45.5 0.4 4.1e-11 42.9 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG10778.1 - 4e-08 32.6 0.1 2.7e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG10778.1 - 9.9e-07 28.2 0.2 0.00031 20.0 0.2 2.6 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG10778.1 - 3.7e-06 26.9 0.0 6.9e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG10778.1 - 4.9e-06 25.9 0.0 8.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG10778.1 - 2.2e-05 23.7 0.0 8e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Mito_carr PF00153.27 OAG10779.1 - 5.8e-31 106.3 2.3 1.5e-14 53.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 OAG10780.1 - 2e-65 219.3 0.6 2.4e-65 219.1 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG10780.1 - 7.7e-36 122.9 0.1 1.3e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG10780.1 - 3.2e-16 59.3 0.1 3.9e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAG10780.1 - 2.1e-05 24.5 0.4 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG10780.1 - 2.7e-05 24.2 0.0 8.7e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG10780.1 - 4.9e-05 23.0 0.5 0.00013 21.6 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG10780.1 - 0.00025 20.5 0.1 0.00031 20.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 OAG10780.1 - 0.00028 21.3 0.0 0.15 12.5 0.0 2.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 OAG10780.1 - 0.00056 19.4 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAG10780.1 - 0.0009 18.8 0.0 0.0051 16.4 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OAG10780.1 - 0.0092 16.4 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG10780.1 - 0.031 14.5 0.0 0.068 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG10780.1 - 0.046 13.7 0.1 0.13 12.2 0.0 1.9 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OAG10780.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 OAG10780.1 - 0.071 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 OAG10780.1 - 0.088 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 OAG10780.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OAG10780.1 - 0.1 12.3 0.1 0.66 9.7 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OAG10780.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 OAG10780.1 - 0.16 11.5 0.1 1.5 8.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain Chorismate_bind PF00425.18 OAG10781.1 - 4.6e-64 216.5 0.1 9.8e-35 120.3 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme MFS_1 PF07690.16 OAG10781.1 - 4e-30 104.9 32.6 9.9e-26 90.5 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GATase PF00117.28 OAG10781.1 - 3.6e-23 82.3 0.0 1.2e-22 80.6 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OAG10781.1 - 7.4e-14 52.2 0.0 1.6e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OAG10781.1 - 1.2e-05 25.2 0.8 6.6e-05 22.8 0.8 2.1 1 1 0 1 1 1 1 Peptidase C26 MFS_2 PF13347.6 OAG10781.1 - 1.3e-05 24.0 13.9 0.012 14.2 6.0 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 OAG10781.1 - 0.00027 20.0 8.9 0.0012 17.8 2.3 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAG10781.1 - 0.00077 18.4 11.0 0.023 13.6 3.6 2.5 2 1 0 2 2 2 2 MFS_1 like family Acetyltransf_1 PF00583.25 OAG10782.1 - 3.3e-06 27.3 0.1 3.7e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG10782.1 - 1.4e-05 25.1 0.0 1.6e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG10782.1 - 3.2e-05 24.0 0.1 3.6e-05 23.8 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG10782.1 - 3.7e-05 24.1 0.0 4.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG10782.1 - 0.00028 21.0 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG10782.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 FR47-like protein Vps51 PF08700.11 OAG10784.1 - 3.2e-13 49.5 0.0 2e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 GCIP PF13324.6 OAG10784.1 - 1.7 8.2 6.9 0.21 11.2 1.8 2.1 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting D123 PF07065.14 OAG10785.1 - 1.4e-117 392.3 0.1 1.7e-117 392.0 0.1 1.1 1 0 0 1 1 1 1 D123 cwf21 PF08312.12 OAG10786.1 - 9.2e-18 64.1 13.5 9.2e-18 64.1 13.5 2.5 2 1 0 2 2 2 1 cwf21 domain Chisel PF15355.6 OAG10787.1 - 0.025 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel PHO4 PF01384.20 OAG10789.1 - 1.5e-99 333.2 18.5 1.8e-99 333.0 18.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family adh_short PF00106.25 OAG10791.1 - 2.8e-23 82.4 0.1 4.9e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10791.1 - 3.2e-17 62.9 0.1 6.1e-17 61.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2267 PF10025.9 OAG10791.1 - 0.045 14.0 0.3 1.6 9.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Elong_Iki1 PF10483.9 OAG10792.1 - 1.4e-82 277.6 0.0 1.6e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 MFS_1 PF07690.16 OAG10794.1 - 2.6e-28 99.0 38.6 1.1e-25 90.3 37.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fes1 PF08609.10 OAG10795.1 - 1e-25 90.4 0.5 2.8e-25 89.0 0.5 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 OAG10795.1 - 1e-06 29.0 1.4 1.2e-06 28.8 0.3 1.7 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.23 OAG10795.1 - 3.8e-06 26.7 0.4 0.016 15.2 0.2 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OAG10795.1 - 1.1e-05 25.2 1.2 0.024 14.9 0.1 3.0 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 OAG10795.1 - 1.3e-05 25.6 0.2 0.00035 21.0 0.7 2.4 1 1 1 2 2 2 2 HEAT-like repeat HrpB4 PF09502.10 OAG10795.1 - 0.0094 15.8 0.2 0.014 15.3 0.2 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB4) Actin PF00022.19 OAG10796.1 - 2.9e-150 500.4 0.0 1.1e-149 498.5 0.0 1.7 1 1 0 1 1 1 1 Actin PAC3 PF10178.9 OAG10797.1 - 7.9e-07 29.1 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 OAG10798.1 - 5.3e-19 68.5 0.0 5.3e-19 68.5 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG10798.1 - 1.2e-12 48.2 0.0 6.3e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OAG10798.1 - 3.5e-08 33.7 0.0 9.9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OAG10798.1 - 1.8e-07 31.1 0.3 5e-07 29.7 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG10798.1 - 7.1e-05 23.1 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG10798.1 - 0.0016 18.8 0.1 0.0033 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG10798.1 - 0.0043 16.8 0.1 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG10798.1 - 0.012 15.6 5.0 1.1 9.2 0.0 3.3 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit PhoH PF02562.16 OAG10798.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 OAG10798.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Sugar_tr PF00083.24 OAG10799.1 - 2e-79 267.6 22.9 2.3e-79 267.4 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10799.1 - 2.4e-15 56.3 23.4 2.4e-15 56.3 23.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG10799.1 - 0.0014 17.1 3.6 0.0014 17.1 3.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HTH_22 PF13309.6 OAG10799.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 HTH domain Methyltransf_25 PF13649.6 OAG10801.1 - 0.00035 21.2 0.0 0.00094 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 OAG10801.1 - 0.0013 19.3 1.0 0.0025 18.4 0.1 2.0 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 OAG10801.1 - 0.0016 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 OAG10801.1 - 0.082 12.2 0.0 0.34 10.2 0.0 1.9 2 1 1 3 3 3 0 RNA methyltransferase T2SSM PF04612.12 OAG10801.1 - 0.13 12.3 1.8 0.19 11.8 0.2 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Cellulase PF00150.18 OAG10802.1 - 4.6e-18 65.6 0.0 8e-18 64.8 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TrbI PF03743.14 OAG10802.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein PGDYG PF14083.6 OAG10802.1 - 0.13 12.5 0.2 8.8 6.6 0.2 2.4 2 0 0 2 2 2 0 PGDYG protein NmrA PF05368.13 OAG10803.1 - 6.7e-47 160.0 0.0 8.5e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG10803.1 - 5.9e-13 49.1 0.1 7.9e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG10803.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAG10803.1 - 0.00086 19.5 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 OAG10803.1 - 0.029 13.9 0.2 0.079 12.5 0.2 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Suc_Fer-like PF06999.12 OAG10804.1 - 2e-43 148.6 0.0 2.4e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1 PF00133.22 OAG10805.1 - 4.3e-52 177.2 0.0 7.2e-32 110.4 0.1 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 OAG10805.1 - 9.9e-39 132.8 0.0 1.9e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 OAG10805.1 - 1.1e-24 87.0 0.5 2.6e-18 65.9 0.0 4.4 4 1 1 5 5 5 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAG10805.1 - 1.1e-10 41.7 0.0 2.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAG10805.1 - 0.0023 17.3 0.0 1.1 8.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain AA_permease_2 PF13520.6 OAG10806.1 - 1.9e-64 218.1 43.1 3.1e-64 217.4 43.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG10806.1 - 3.1e-28 98.6 24.9 3.1e-28 98.6 24.9 2.3 2 1 0 2 2 2 1 Amino acid permease Peptidase_C69 PF03577.15 OAG10807.1 - 3.1e-20 72.5 0.1 4.6e-20 71.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C69 Dabb PF07876.12 OAG10808.1 - 2.8e-13 50.3 0.1 3.2e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain adh_short_C2 PF13561.6 OAG10809.1 - 1.1e-52 178.9 0.2 1.4e-52 178.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG10809.1 - 4.8e-47 160.0 1.1 6.1e-47 159.6 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG10809.1 - 8.2e-13 48.7 0.2 1.1e-12 48.2 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG10809.1 - 0.016 14.7 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG10809.1 - 0.019 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 OAG10809.1 - 0.067 13.1 0.2 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAG10810.1 - 7.2e-23 81.1 19.8 7.2e-23 81.1 19.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG10810.1 - 1.5e-07 30.7 1.8 1.5e-07 30.7 1.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG10810.1 - 0.023 13.1 0.2 0.037 12.5 0.2 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Glt_symporter PF03616.14 OAG10810.1 - 0.067 11.9 0.1 0.13 10.9 0.1 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter Fungal_trans_2 PF11951.8 OAG10811.1 - 0.013 14.3 0.2 0.024 13.5 0.2 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain CVNH PF08881.10 OAG10812.1 - 8.8e-33 113.0 0.1 1.9e-32 111.9 0.1 1.6 1 0 0 1 1 1 1 CVNH domain LysM PF01476.20 OAG10812.1 - 4.3e-12 45.9 0.0 8.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.15 OAG10812.1 - 0.0015 18.3 16.5 0.0015 18.3 16.5 2.4 2 0 0 2 2 2 1 Glycine zipper 2TM domain Pex14_N PF04695.13 OAG10812.1 - 0.024 15.3 6.1 0.039 14.6 6.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CRISPR_Cse1 PF09481.10 OAG10812.1 - 0.037 13.1 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Extensin_2 PF04554.13 OAG10812.1 - 0.34 11.0 11.7 0.65 10.1 11.7 1.4 1 0 0 1 1 1 0 Extensin-like region DUF2076 PF09849.9 OAG10812.1 - 3.4 7.6 28.4 12 5.8 28.4 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Piwi PF02171.17 OAG10813.1 - 1.3e-72 244.6 0.0 2.1e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAG10813.1 - 1.6e-17 64.4 0.1 3e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAG10813.1 - 1.2e-15 56.9 0.3 2.6e-15 55.8 0.3 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 OAG10813.1 - 3.2e-10 40.2 0.0 8.8e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 OAG10813.1 - 8.1e-09 35.4 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 OAG10813.1 - 0.0024 18.1 0.0 0.0058 16.9 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute PRKCSH-like PF12999.7 OAG10813.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like HTH_OrfB_IS605 PF12323.8 OAG10813.1 - 0.2 11.2 0.5 0.56 9.7 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Zds_C PF08632.10 OAG10814.1 - 0.054 13.3 0.3 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term MHCassoc_trimer PF08831.10 OAG10814.1 - 3.5 7.7 11.1 15 5.7 0.3 2.7 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Sld7_C PF18596.1 OAG10815.1 - 8.1e-30 102.8 0.3 1.5e-29 102.0 0.3 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain Sld7_N PF18636.1 OAG10815.1 - 0.025 14.9 0.1 0.069 13.5 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain DUF4267 PF14087.6 OAG10816.1 - 2.9e-19 69.2 5.2 3.4e-19 69.0 5.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Glyco_hydro_63 PF03200.16 OAG10817.1 - 8.3e-174 578.9 3.4 8.3e-174 578.9 3.4 3.0 3 1 0 3 3 3 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OAG10817.1 - 2.6e-83 279.6 0.0 1.2e-82 277.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 OAG10817.1 - 0.0094 14.8 6.3 0.0074 15.2 1.8 2.1 1 1 1 2 2 2 1 Trehalase SNRNP27 PF08648.12 OAG10818.1 - 3.8e-24 84.5 2.1 7.9e-24 83.5 2.1 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins RNA_polI_A34 PF08208.11 OAG10818.1 - 4.7 7.2 10.0 30 4.6 10.0 1.9 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NMT1 PF09084.11 OAG10819.1 - 2.1e-75 253.4 0.0 2.7e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 OAG10819.1 - 3.1e-05 23.8 0.0 0.15 11.7 0.0 3.4 3 1 1 4 4 4 2 NMT1-like family Phosphonate-bd PF12974.7 OAG10819.1 - 0.032 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Cation_efflux PF01545.21 OAG10822.1 - 7.4e-27 94.4 15.1 1.2e-26 93.7 15.1 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG10822.1 - 1e-09 38.4 0.2 2.1e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Zip PF02535.22 OAG10824.1 - 1.6e-48 165.7 3.8 4.6e-48 164.2 3.8 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Zn_clus PF00172.18 OAG10825.1 - 6.9e-05 22.9 9.9 0.00014 21.9 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 OAG10826.1 - 9.1e-23 80.9 1.8 2e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG10826.1 - 1.4e-13 51.1 0.2 1.3e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 OAG10826.1 - 2.4e-05 24.5 0.5 0.00057 20.1 0.5 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 OAG10826.1 - 0.00016 21.9 0.4 0.43 10.7 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain DUF4844 PF16133.5 OAG10826.1 - 0.068 13.7 0.0 0.29 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) ATP-synt_Eps PF04627.13 OAG10827.1 - 0.044 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain PPDFL PF15060.6 OAG10827.1 - 2.5 8.7 7.1 0.27 11.7 1.7 2.1 2 0 0 2 2 2 0 Differentiation and proliferation regulator 4HBT_2 PF13279.6 OAG10828.1 - 3.9e-05 24.1 0.0 5.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily SUI1 PF01253.22 OAG10829.1 - 4.9e-22 78.2 0.0 1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 OAG10829.1 - 2.1e-06 28.3 0.4 0.091 13.5 0.0 2.7 3 0 0 3 3 3 2 Pre-PUA-like domain Kin17_mid PF10357.9 OAG10829.1 - 0.013 15.5 0.1 0.056 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 OAG10829.1 - 0.02 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain RNase_HII PF01351.18 OAG10830.1 - 3.2e-47 160.9 0.0 9.5e-46 156.1 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease HII AWPM-19 PF05512.11 OAG10830.1 - 0.031 14.4 0.1 0.051 13.8 0.1 1.4 1 0 0 1 1 1 0 AWPM-19-like family FAM219A PF15260.6 OAG10831.1 - 0.034 14.5 1.7 0.071 13.5 1.5 1.6 1 1 0 1 1 1 0 Protein family FAM219A ABC_tran_CTD PF16326.5 OAG10832.1 - 0.00089 19.5 0.0 0.0061 16.8 0.1 1.9 2 0 0 2 2 2 1 ABC transporter C-terminal domain DUF2303 PF10065.9 OAG10832.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) ER_lumen_recept PF00810.18 OAG10833.1 - 5.7e-55 186.2 9.3 1e-54 185.4 9.3 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OAG10833.1 - 0.25 11.1 13.2 0.7 9.7 0.2 4.1 4 1 1 5 5 5 0 PQ loop repeat Glyco_hydro_85 PF03644.13 OAG10834.1 - 2.4e-75 253.7 0.0 3.7e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF445 PF04286.12 OAG10835.1 - 3e-05 24.0 12.3 3e-05 24.0 12.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF445) DUF19 PF01579.18 OAG10835.1 - 0.058 13.2 0.8 0.11 12.3 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF19) Snapin_Pallidin PF14712.6 OAG10835.1 - 1.2 9.6 9.8 0.14 12.6 2.0 3.5 3 1 1 4 4 4 0 Snapin/Pallidin DUF1104 PF06518.11 OAG10835.1 - 3.5 8.0 6.5 1.2 9.6 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF4509 PF14970.6 OAG10835.1 - 5.7 6.8 9.6 0.21 11.5 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) MARVEL PF01284.23 OAG10836.1 - 3.1e-13 50.0 15.9 4e-13 49.6 15.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain TNFR_16_TM PF18422.1 OAG10836.1 - 0.081 12.9 0.3 0.081 12.9 0.3 2.3 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain adh_short PF00106.25 OAG10838.1 - 2.3e-38 131.6 0.0 3e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10838.1 - 6.4e-26 91.3 0.0 9.6e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10838.1 - 5.5e-09 36.2 0.6 4.4e-08 33.2 0.6 2.1 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG10838.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAG10838.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG10838.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3180 PF11377.8 OAG10839.1 - 0.087 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) MBOAT_2 PF13813.6 OAG10842.1 - 7.8e-19 67.7 6.6 1.9e-18 66.5 6.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CCB1 PF12046.8 OAG10842.1 - 0.34 10.2 2.7 0.18 11.2 0.4 1.7 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Aconitase PF00330.20 OAG10844.1 - 1.2e-111 374.0 1.2 1.5e-110 370.4 1.2 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG10844.1 - 2e-26 92.8 0.0 5.1e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_5 PF00266.19 OAG10845.1 - 2.9e-28 98.9 0.0 1.9e-17 63.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DUF1254 PF06863.12 OAG10845.1 - 0.12 12.5 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1254) DUF3341 PF11821.8 OAG10846.1 - 1.5 8.5 6.8 3.4 7.3 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) HobA PF12163.8 OAG10848.1 - 0.045 13.3 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 DNA replication regulator Glyco_hydro_3_C PF01915.22 OAG10849.1 - 2.1e-36 125.8 0.1 3.5e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG10849.1 - 9.6e-30 104.0 0.0 1.5e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG10849.1 - 5.5e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Beta-lactamase PF00144.24 OAG10850.1 - 1.3e-38 133.1 0.0 1.9e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 OAG10850.1 - 0.0076 15.9 0.0 0.075 12.6 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase enzyme family Histone_H2A_C PF16211.5 OAG10851.1 - 1.1 9.1 3.6 7.6 6.4 0.0 2.8 3 0 0 3 3 3 0 C-terminus of histone H2A Sugar_tr PF00083.24 OAG10852.1 - 1.2e-18 67.2 13.5 6e-18 64.9 12.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10852.1 - 3.8e-18 65.5 33.8 1.5e-14 53.7 14.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.22 OAG10853.1 - 1.3e-98 331.2 0.8 1.7e-98 330.8 0.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MetallophosN PF16371.5 OAG10853.1 - 0.051 13.8 0.3 1.5 9.2 0.0 3.1 3 0 0 3 3 3 0 N terminal of Calcineurin-like phosphoesterase DUF3384 PF11864.8 OAG10854.1 - 4.1e-105 352.4 3.7 6.1e-105 351.9 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 OAG10854.1 - 2.9e-50 170.4 0.0 5e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 OAG10854.1 - 1.3e-36 126.5 6.6 1.9e-32 112.8 1.1 3.7 4 0 0 4 4 4 3 Tuberin CAS_CSE1 PF03378.15 OAG10855.1 - 9.1e-175 581.4 1.0 9.1e-175 581.4 1.0 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 OAG10855.1 - 3.6e-149 496.6 3.2 5.5e-149 496.0 3.2 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 OAG10855.1 - 1.8e-16 59.8 0.1 7.4e-15 54.6 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAG10855.1 - 0.24 11.4 4.0 0.46 10.5 0.0 3.6 4 0 0 4 4 4 0 Exportin 1-like protein tRNA_SAD PF07973.14 OAG10856.1 - 2.6e-05 24.2 0.8 5.3e-05 23.2 0.8 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 OAG10856.1 - 0.0055 15.3 0.0 0.0075 14.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) 4HBT PF03061.22 OAG10858.1 - 1.3e-05 25.5 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily DUF2670 PF10875.8 OAG10858.1 - 0.09 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) p450 PF00067.22 OAG10859.1 - 0.00042 19.2 0.0 0.00042 19.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mso1_Sec1_bdg PF14475.6 OAG10861.1 - 9.7e-20 69.9 0.1 2.1e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 Sec1-binding region of Mso1 LEA_6 PF10714.9 OAG10861.1 - 1.4 9.0 9.4 0.32 11.1 1.7 2.8 2 1 0 2 2 2 0 Late embryogenesis abundant protein 18 RabGAP-TBC PF00566.18 OAG10862.1 - 2.5e-39 135.2 3.5 6.2e-39 133.9 3.5 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 OAG10862.1 - 3.4e-08 33.2 0.0 3.3e-05 23.4 0.1 3.3 2 1 0 2 2 2 2 Rab-binding domain (RBD) Transglut_core3 PF13471.6 OAG10863.1 - 0.07 13.0 0.2 0.2 11.5 0.2 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2011 PF09428.10 OAG10865.1 - 1.4e-19 70.2 2.7 4.5e-19 68.5 0.0 2.5 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF2011) NPR3 PF03666.13 OAG10865.1 - 0.11 11.3 6.8 0.17 10.7 6.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 OAG10865.1 - 0.74 9.5 4.7 1.1 9.0 4.7 1.2 1 0 0 1 1 1 0 Connexin AAA_11 PF13086.6 OAG10865.1 - 2.1 8.1 10.1 3.8 7.2 10.1 1.3 1 0 0 1 1 1 0 AAA domain Casc1_N PF15927.5 OAG10865.1 - 7.2 6.2 19.4 13 5.4 19.4 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Pyr_redox_2 PF07992.14 OAG10866.1 - 0.00079 18.7 0.0 0.057 12.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SP_C-Propep PF08999.10 OAG10867.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF1254 PF06863.12 OAG10869.1 - 2.7e-07 30.7 0.0 6.3e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1254) Amidohydro_3 PF07969.11 OAG10870.1 - 5.7e-53 181.0 1.1 6.7e-53 180.8 1.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG10870.1 - 2.7e-14 53.3 5.1 5.6e-13 48.9 0.7 3.0 1 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 OAG10871.1 - 3.6e-33 114.9 34.1 3.6e-33 114.9 34.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG10871.1 - 2.7e-08 33.1 11.8 2.7e-08 33.1 11.8 2.0 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAG10871.1 - 0.083 11.2 0.1 0.083 11.2 0.1 2.8 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OAG10872.1 - 4.4e-34 117.9 17.2 1.8e-33 116.0 18.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG10872.1 - 0.0001 21.8 2.1 0.0001 21.8 2.1 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB 2OG-FeII_Oxy PF03171.20 OAG10873.1 - 3.7e-12 46.6 0.0 7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG10873.1 - 5.7e-12 46.4 0.1 1.3e-11 45.3 0.1 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2284 PF10050.9 OAG10874.1 - 0.0003 20.6 1.4 0.44 10.3 0.0 3.1 3 0 0 3 3 3 2 Predicted metal-binding protein (DUF2284) Strep_his_triad PF04270.13 OAG10874.1 - 0.33 11.0 6.3 38 4.4 0.0 3.3 3 0 0 3 3 3 0 Streptococcal histidine triad protein MDH PF02315.16 OAG10874.1 - 1.1 9.3 6.1 9.9 6.3 0.1 2.6 2 1 0 2 2 2 0 Methanol dehydrogenase beta subunit Rubredoxin PF00301.20 OAG10874.1 - 4.6 7.4 7.3 62 3.7 0.3 3.3 3 0 0 3 3 3 0 Rubredoxin ADH_zinc_N PF00107.26 OAG10875.1 - 1e-14 54.6 0.0 2.3e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG10875.1 - 1.2e-13 52.3 0.0 2.4e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_3 PF03447.16 OAG10875.1 - 0.016 15.9 0.0 0.046 14.4 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG10875.1 - 0.065 13.4 0.2 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Prot_ATP_ID_OB PF16450.5 OAG10875.1 - 0.098 12.6 0.0 0.46 10.5 0.0 2.1 3 0 0 3 3 3 0 Proteasomal ATPase OB C-terminal domain Glyco_hydro_6 PF01341.17 OAG10876.1 - 5.2e-51 174.2 0.0 7e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 EHN PF06441.12 OAG10877.1 - 7.6e-34 116.3 3.4 1.4e-33 115.5 0.3 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG10877.1 - 4.5e-11 42.9 0.0 7.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold CAP PF00188.26 OAG10879.1 - 6.6e-16 59.3 4.9 1.1e-15 58.6 4.9 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ArsB PF02040.15 OAG10880.1 - 1.6e-08 34.3 20.5 7e-07 28.9 9.4 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein Plasmodium_Vir PF05795.11 OAG10880.1 - 0.27 10.6 0.3 22 4.3 0.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein F-box-like PF12937.7 OAG10882.1 - 1.4e-06 28.1 0.9 4.1e-06 26.6 0.9 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 OAG10882.1 - 0.012 15.5 0.2 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 F-box domain FlxA PF14282.6 OAG10883.1 - 0.65 10.0 11.8 16 5.5 0.0 2.5 1 1 1 2 2 2 0 FlxA-like protein Vir_act_alpha_C PF10400.9 OAG10883.1 - 0.85 10.4 4.9 7.6 7.3 4.7 2.6 2 1 0 2 2 2 0 Virulence activator alpha C-term NPV_P10 PF05531.12 OAG10883.1 - 1.5 9.3 4.9 15 6.2 0.4 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_23 PF13476.6 OAG10883.1 - 2.1 8.8 8.2 3.3 8.2 8.2 1.3 1 0 0 1 1 1 0 AAA domain JmjC PF02373.22 OAG10884.1 - 8.1e-38 129.4 0.8 2e-37 128.1 0.8 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 OAG10884.1 - 1.3e-18 67.1 1.6 2.3e-18 66.4 1.6 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAG10884.1 - 1.9e-18 66.5 2.9 3.3e-18 65.7 2.9 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 OAG10884.1 - 1.2e-14 54.0 0.7 4.4e-14 52.2 0.5 2.2 2 0 0 2 2 2 1 jmjN domain PHD PF00628.29 OAG10884.1 - 0.35 10.8 3.3 0.88 9.5 3.3 1.7 1 0 0 1 1 1 0 PHD-finger Aldedh PF00171.22 OAG10885.1 - 1.6e-153 511.5 0.1 2e-153 511.3 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 OAG10885.1 - 6.7e-17 61.4 0.0 1.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain LuxC PF05893.14 OAG10885.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) SnoaL_4 PF13577.6 OAG10886.1 - 2e-29 102.3 0.1 2.6e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain PAH PF02671.21 OAG10886.1 - 0.013 15.7 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat Amidohydro_2 PF04909.14 OAG10887.1 - 6.7e-39 134.4 0.3 8.6e-39 134.0 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase Cas9_b_hairpin PF17893.1 OAG10887.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain RPE65 PF03055.15 OAG10888.1 - 4.3e-103 346.0 0.0 5.3e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glyco_transf_90 PF05686.12 OAG10890.1 - 5.6e-21 74.9 0.2 3.5e-17 62.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OAG10890.1 - 0.061 13.7 0.1 0.17 12.3 0.1 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 DUF3328 PF11807.8 OAG10891.1 - 4e-43 147.7 0.2 4.9e-43 147.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sen15 PF09631.10 OAG10892.1 - 6.1e-25 87.4 0.0 8.6e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein DUF1772 PF08592.11 OAG10896.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) SOG2 PF10428.9 OAG10899.1 - 1.8 7.7 9.4 1.8 7.7 9.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2985 PF11204.8 OAG10900.1 - 2.3e-37 127.0 2.2 4.7e-37 126.0 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) TFIIA PF03153.13 OAG10901.1 - 0.00029 20.9 10.3 0.00038 20.6 10.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Rick_17kDa_Anti PF05433.15 OAG10901.1 - 0.023 14.5 8.6 0.051 13.5 8.6 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF456 PF04306.13 OAG10901.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Fungal_trans PF04082.18 OAG10904.1 - 6.7e-26 90.9 0.0 1.2e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG10904.1 - 1.2e-09 38.1 10.9 2.4e-09 37.2 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPHH PF16905.5 OAG10906.1 - 0.073 12.9 0.4 0.37 10.6 0.0 2.3 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated Hydrolase_6 PF13344.6 OAG10908.1 - 0.037 14.1 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Apc13p PF05839.11 OAG10908.1 - 0.078 13.2 0.5 0.32 11.2 0.5 2.1 1 0 0 1 1 1 0 Apc13p protein RicinB_lectin_2 PF14200.6 OAG10909.1 - 0.0016 19.1 1.6 0.0026 18.4 0.4 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like COesterase PF00135.28 OAG10910.1 - 1.8e-84 284.5 0.0 2.4e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG10910.1 - 5.8e-08 32.9 0.4 4.1e-07 30.1 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG10910.1 - 0.00098 18.6 0.4 0.0022 17.5 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OAG10910.1 - 0.015 14.2 0.0 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase BatA PF07584.11 OAG10911.1 - 0.28 11.6 3.5 0.54 10.7 0.0 2.8 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Pkinase PF00069.25 OAG10912.1 - 2.4e-18 66.5 0.0 3.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG10912.1 - 5.2e-13 48.9 0.0 1.2e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG10912.1 - 0.0072 16.3 0.2 0.093 12.6 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 OAG10913.1 - 4.2e-25 88.6 0.0 7.7e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG10913.1 - 1e-13 51.2 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG10913.1 - 0.01 15.2 0.1 0.024 14.0 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG10913.1 - 0.022 14.1 0.0 0.079 12.3 0.0 1.7 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 OAG10913.1 - 0.086 12.7 0.0 1.2 9.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DJ-1_PfpI PF01965.24 OAG10914.1 - 1.4e-13 50.9 0.0 2.6e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family Sugar_tr PF00083.24 OAG10915.1 - 1.1e-129 433.2 26.4 1.3e-129 433.0 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG10915.1 - 1.4e-25 90.0 54.9 1.5e-21 76.7 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 OAG10915.1 - 0.052 13.6 1.9 0.38 10.9 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Arteri_Gl PF00951.18 OAG10915.1 - 5.7 6.7 11.8 0.17 11.7 2.1 2.3 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF3810 PF12725.7 OAG10916.1 - 1.1 8.5 5.5 1.9 7.7 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4131 PF13567.6 OAG10916.1 - 2.4 7.8 9.0 0.092 12.4 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Myb_DNA-binding PF00249.31 OAG10917.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG10917.1 - 0.028 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Myb DNA-binding like HET PF06985.11 OAG10918.1 - 1.1e-21 77.7 0.5 7.1e-21 75.1 0.0 2.3 1 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 OAG10918.1 - 4.9e-06 27.1 1.9 0.0084 16.7 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG10918.1 - 0.0062 17.0 0.0 1.8 9.4 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat DUF1192 PF06698.11 OAG10918.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) PDR_assoc PF08370.11 OAG10918.1 - 0.15 11.8 0.0 0.48 10.2 0.0 1.8 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Ank_5 PF13857.6 OAG10918.1 - 0.17 12.2 0.0 1.8 9.0 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) ABC_tran PF00005.27 OAG10919.1 - 1.2e-46 158.6 0.0 1e-22 81.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OAG10919.1 - 1e-25 90.6 36.4 4.6e-13 49.0 7.7 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 OAG10919.1 - 9.2e-24 84.8 0.0 1.6e-06 28.1 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG10919.1 - 2.7e-13 49.9 0.3 0.00079 18.9 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAG10919.1 - 3e-08 33.8 0.2 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 OAG10919.1 - 4.2e-08 33.9 0.6 0.012 16.2 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG10919.1 - 2e-07 30.7 0.8 0.0078 15.9 0.1 3.1 2 1 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG10919.1 - 3.9e-06 27.4 0.2 0.11 12.9 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 OAG10919.1 - 8.9e-05 23.1 0.0 0.024 15.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) Rad17 PF03215.15 OAG10919.1 - 0.0001 22.3 0.2 0.1 12.5 0.0 2.7 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_15 PF13175.6 OAG10919.1 - 0.00011 22.0 0.0 3.9 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG10919.1 - 0.00012 22.4 0.2 0.3 11.4 0.1 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAG10919.1 - 0.00015 22.1 0.0 0.041 14.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 OAG10919.1 - 0.00039 20.2 0.8 1.6 8.4 0.0 3.0 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 OAG10919.1 - 0.0015 18.3 0.2 27 4.4 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_27 PF13514.6 OAG10919.1 - 0.0027 17.3 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG10919.1 - 0.0055 17.1 0.0 4.8 7.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 OAG10919.1 - 0.0056 16.9 0.1 6.4 7.1 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_PrkA PF08298.11 OAG10919.1 - 0.0064 15.5 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 2 PrkA AAA domain MMR_HSR1 PF01926.23 OAG10919.1 - 0.0092 16.1 0.6 4.7 7.3 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OAG10919.1 - 0.015 15.0 0.1 4.9 6.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 OAG10919.1 - 0.018 14.5 0.1 0.65 9.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 OAG10919.1 - 0.026 13.7 0.1 4.4 6.4 0.0 2.7 2 1 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 OAG10919.1 - 0.033 13.4 0.3 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 OAG10919.1 - 0.059 13.3 0.1 15 5.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_13 PF13166.6 OAG10919.1 - 0.094 11.3 0.0 11 4.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 OAG10919.1 - 0.095 12.0 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 AIG1 family TsaE PF02367.17 OAG10919.1 - 0.13 12.3 0.1 26 4.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OAG10919.1 - 0.14 12.1 0.0 16 5.5 0.1 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 OAG10919.1 - 0.2 11.2 0.2 7.4 6.1 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 OAG10919.1 - 0.31 11.3 0.8 27 5.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain Phage_TAC_1 PF06222.11 OAG10920.1 - 0.12 12.2 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone Toxin_38 PF14866.6 OAG10921.1 - 0.021 15.1 0.8 0.041 14.2 0.8 1.4 1 0 0 1 1 1 0 Potassium channel toxin Kri1_C PF12936.7 OAG10923.1 - 1.1e-28 99.2 0.4 1.1e-28 99.2 0.4 4.4 6 1 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 OAG10923.1 - 1.3e-23 83.5 22.6 1.3e-23 83.5 22.6 4.8 5 1 2 7 7 7 1 KRI1-like family FANCI_S4 PF14678.6 OAG10923.1 - 4.5 6.3 6.1 0.33 10.0 0.4 1.9 2 0 0 2 2 2 0 FANCI solenoid 4 VASt PF16016.5 OAG10924.1 - 5.2e-27 95.1 0.0 1e-26 94.2 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 OAG10924.1 - 3.8e-16 59.5 0.0 6.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 OAG10924.1 - 4.2e-10 40.1 0.2 2.1e-09 37.8 0.1 2.3 3 0 0 3 3 3 1 PH domain BAR PF03114.18 OAG10924.1 - 0.0039 16.9 0.1 0.0099 15.5 0.1 1.6 1 0 0 1 1 1 1 BAR domain GRAM PF02893.20 OAG10924.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 GRAM domain MFS_1 PF07690.16 OAG10925.1 - 4.4e-13 48.9 40.6 6.2e-13 48.4 40.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG10925.1 - 6.7e-06 25.9 7.9 6.7e-06 25.9 7.9 2.8 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 Pec_lyase_C PF00544.19 OAG10926.1 - 1.3e-13 51.0 7.2 3.4e-12 46.4 7.2 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAG10926.1 - 0.00011 22.1 13.5 0.0014 18.5 7.4 2.4 1 1 1 2 2 2 2 Right handed beta helix region FYTT PF07078.11 OAG10927.1 - 0.15 11.3 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Forty-two-three protein MFS_1 PF07690.16 OAG10928.1 - 2.5e-24 85.9 21.9 2.5e-24 85.9 21.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 OAG10930.1 - 9.8e-28 96.9 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10930.1 - 8.7e-15 54.9 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG10930.1 - 4.4e-06 26.7 0.0 7.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG10930.1 - 0.0048 16.3 0.1 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 OAG10931.1 - 2.7e-33 115.4 3.9 1.1e-32 113.3 3.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain IBR PF01485.21 OAG10932.1 - 8.1e-22 77.2 38.5 1.2e-14 54.3 1.2 4.2 3 1 1 4 4 4 4 IBR domain, a half RING-finger domain RWD PF05773.22 OAG10932.1 - 8e-19 68.0 0.0 1.6e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 OAG10932.1 - 0.0014 18.9 10.0 0.0014 18.9 10.0 4.4 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 OAG10932.1 - 0.0028 17.5 10.4 0.0028 17.5 10.4 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG10932.1 - 0.022 14.5 6.2 0.022 14.5 6.2 2.6 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_5 PF14634.6 OAG10932.1 - 0.025 14.5 11.8 0.025 14.5 11.8 3.8 2 1 1 3 3 3 0 zinc-RING finger domain PAP2 PF01569.21 OAG10933.1 - 4.9e-13 49.0 2.7 4.9e-13 49.0 2.7 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 OAG10933.1 - 0.0024 18.0 0.1 0.092 12.9 0.0 2.2 1 1 0 2 2 2 1 Divergent PAP2 family Phage_holin_3_1 PF05106.12 OAG10933.1 - 0.088 13.3 3.2 4.9 7.6 0.6 2.3 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Polysacc_synt_C PF14667.6 OAG10933.1 - 0.092 12.8 3.5 0.19 11.8 3.5 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.6 OAG10933.1 - 3 7.5 9.4 1.8 8.2 4.8 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) MerC PF03203.14 OAG10935.1 - 0.035 14.5 1.4 0.035 14.5 1.4 1.4 2 0 0 2 2 2 0 MerC mercury resistance protein TauE PF01925.19 OAG10935.1 - 0.1 12.2 5.1 0.11 12.1 4.4 1.4 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE HlyU PF10115.9 OAG10936.1 - 0.023 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional activator HlyU ABC2_membrane PF01061.24 OAG10937.1 - 9.6e-86 286.5 45.8 2.9e-45 154.3 19.4 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAG10937.1 - 5.5e-39 133.8 0.0 2.9e-19 69.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG10937.1 - 8.5e-22 76.9 7.0 8.5e-21 73.7 0.0 3.5 3 0 0 3 3 2 1 CDR ABC transporter AAA_16 PF13191.6 OAG10937.1 - 2.1e-06 28.2 0.6 0.0038 17.6 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 OAG10937.1 - 1.4e-05 24.4 47.2 0.0039 16.3 20.4 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.6 OAG10937.1 - 6e-05 23.3 0.1 0.43 10.8 0.1 2.7 2 1 0 2 2 2 2 AAA domain ABC_trans_N PF14510.6 OAG10937.1 - 0.00012 22.7 0.1 0.00033 21.2 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 OAG10937.1 - 0.00021 21.3 0.2 0.0026 17.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OAG10937.1 - 0.00068 19.3 1.0 0.082 12.7 0.1 3.1 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG10937.1 - 0.0012 19.4 0.1 1.5 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAG10937.1 - 0.0021 17.7 0.3 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG10937.1 - 0.0027 18.0 0.9 0.42 10.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAG10937.1 - 0.0051 16.4 1.5 2 8.0 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OAG10937.1 - 0.01 15.8 0.3 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 OAG10937.1 - 0.023 14.8 0.7 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG10937.1 - 0.024 14.3 0.4 5.2 6.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG10937.1 - 0.14 12.6 0.1 18 5.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 OAG10937.1 - 0.14 11.9 0.0 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAG10937.1 - 0.18 11.9 0.2 23 5.1 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 OAG10937.1 - 0.2 10.9 0.6 5.3 6.3 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 OAG10937.1 - 0.2 11.4 1.4 8.6 6.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 OAG10937.1 - 0.26 11.6 0.7 5.9 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 OAG10938.1 - 2e-07 30.8 0.7 1.1e-06 28.4 0.0 2.7 3 0 0 3 3 3 1 F-box-like Med3 PF11593.8 OAG10939.1 - 2.8 7.0 4.6 5.7 6.0 4.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1640 PF07798.11 OAG10940.1 - 2.6e-42 144.8 3.4 3.2e-42 144.5 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.22 OAG10940.1 - 0.015 15.5 1.0 0.027 14.7 1.0 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Golgin_A5 PF09787.9 OAG10940.1 - 0.021 14.3 3.9 0.033 13.6 3.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 OAG10940.1 - 0.099 12.0 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 OAG10940.1 - 0.15 11.3 1.2 0.22 10.7 1.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ECH_1 PF00378.20 OAG10941.1 - 9.6e-28 97.2 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG10941.1 - 2.5e-17 63.4 0.0 2.8e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pet100 PF09803.9 OAG10942.1 - 2e-20 73.0 1.9 2.8e-20 72.6 1.9 1.3 1 0 0 1 1 1 1 Pet100 Transcrip_reg PF01709.20 OAG10943.1 - 1.9e-71 240.3 1.8 2.2e-71 240.1 1.8 1.0 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.6 OAG10944.1 - 9e-07 29.2 7.2 1.9 9.0 0.0 7.6 5 2 2 8 8 8 2 HEAT repeats HEAT PF02985.22 OAG10944.1 - 1.6e-05 24.8 9.0 9.5 6.8 0.1 7.5 7 0 0 7 7 7 3 HEAT repeat Vac14_Fab1_bd PF12755.7 OAG10944.1 - 0.021 15.4 0.0 0.23 12.1 0.0 2.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAG10944.1 - 0.32 10.5 10.0 22 4.5 0.1 6.1 6 1 1 7 7 7 0 CLASP N terminal PhyH PF05721.13 OAG10946.1 - 0.00022 21.5 0.0 0.00041 20.7 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mito_carr PF00153.27 OAG10947.1 - 1.6e-51 172.2 2.6 6.8e-17 61.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Alpha-amylase_C PF02806.18 OAG10948.1 - 7.7e-27 93.6 0.0 1.7e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 OAG10948.1 - 7.2e-18 64.7 0.1 1.5e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 OAG10948.1 - 2.1e-14 53.9 0.3 1.1e-10 41.6 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AAA_2 PF07724.14 OAG10949.1 - 1.7e-37 129.2 0.0 6.3e-37 127.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OAG10949.1 - 1.2e-14 54.9 0.0 2.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAG10949.1 - 1.8e-08 34.3 0.0 4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAG10949.1 - 1.6e-06 28.2 0.0 4.6e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAG10949.1 - 0.00013 21.4 0.9 0.0032 16.9 0.1 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 OAG10949.1 - 0.0014 19.0 0.3 0.025 14.9 0.3 2.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAG10949.1 - 0.0014 18.3 0.2 0.021 14.5 0.2 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 OAG10949.1 - 0.012 15.1 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 OAG10949.1 - 0.017 14.9 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 OAG10949.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 OAG10949.1 - 0.023 15.1 1.7 0.1 13.0 0.0 2.6 2 2 1 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 OAG10949.1 - 0.026 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAG10949.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAG10949.1 - 0.053 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG10949.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 OAG10949.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 OAG10949.1 - 0.14 12.3 0.0 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 OAG10953.1 - 2.4e-08 34.1 0.1 8e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 OAG10953.1 - 0.009 16.5 0.0 0.033 14.7 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OAG10953.1 - 0.014 15.7 0.0 0.097 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG10953.1 - 0.015 15.7 0.0 0.069 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 OAG10953.1 - 0.017 15.0 0.1 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAG10953.1 - 0.024 13.8 0.1 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 OAG10953.1 - 0.061 13.1 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG10953.1 - 0.1 13.2 0.0 0.41 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 OAG10954.1 - 7.2e-32 110.7 54.1 1.6e-30 106.3 52.1 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG10954.1 - 4.8e-12 45.1 18.8 6.7e-12 44.6 18.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) STT3 PF02516.14 OAG10955.1 - 1 8.2 9.8 0.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Oligosaccharyl transferase STT3 subunit Thioredox_DsbH PF03190.15 OAG10956.1 - 1.2e-71 239.9 0.0 2.1e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 OAG10956.1 - 3.5e-08 33.5 0.0 6.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_76 PF03663.14 OAG10956.1 - 0.0098 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG10956.1 - 0.031 13.4 0.0 6.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 zf-Di19 PF05605.12 OAG10957.1 - 1.1 9.6 5.4 18 5.7 3.4 3.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PAP2 PF01569.21 OAG10958.1 - 0.28 10.9 8.8 0.018 14.8 3.1 1.9 2 0 0 2 2 2 0 PAP2 superfamily Gly-zipper_YMGG PF13441.6 OAG10958.1 - 4.5 7.1 5.8 1 9.2 0.6 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper UPF0444 PF15475.6 OAG10958.1 - 5.7 7.3 8.5 5.6 7.3 0.8 2.8 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 Transp_cyt_pur PF02133.15 OAG10959.1 - 4.2e-32 111.5 37.2 3.5e-31 108.5 37.2 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4328 PF14219.6 OAG10960.1 - 0.0031 17.1 0.2 0.005 16.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) DUF4381 PF14316.6 OAG10960.1 - 0.067 13.4 0.9 0.091 13.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMIE PF16038.5 OAG10960.1 - 0.073 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 TMIE protein HemY_N PF07219.13 OAG10960.1 - 0.12 12.6 1.6 0.15 12.3 1.6 1.2 1 0 0 1 1 1 0 HemY protein N-terminus PUF PF00806.19 OAG10963.1 - 2.6e-64 209.4 13.2 1.4e-09 37.1 0.4 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Phosphodiest PF01663.22 OAG10964.1 - 7e-15 55.5 0.3 1.1e-14 54.8 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG10964.1 - 9.3e-07 28.5 1.0 3e-06 26.8 0.1 2.3 3 0 0 3 3 3 1 Sulfatase Metalloenzyme PF01676.18 OAG10964.1 - 5.3e-05 22.7 1.2 0.0001 21.8 1.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 OAG10964.1 - 0.48 10.5 2.5 6.3 6.9 0.2 2.4 2 0 0 2 2 2 0 PglZ domain RF-1 PF00472.20 OAG10967.1 - 6.3e-25 87.4 3.1 9e-25 86.9 3.1 1.2 1 0 0 1 1 1 1 RF-1 domain SPT_ssu-like PF11779.8 OAG10968.1 - 5.3e-24 83.6 5.5 5.3e-24 83.6 5.5 1.8 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like Gram_pos_anchor PF00746.21 OAG10968.1 - 1.2 9.2 5.4 9.5 6.3 0.4 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif CENP-I PF07778.11 OAG10970.1 - 1.6e-45 155.8 0.0 3.1e-44 151.6 0.0 2.0 1 1 0 1 1 1 1 Mis6 FAD_binding_4 PF01565.23 OAG10972.1 - 3.4e-27 94.9 2.6 4.9e-27 94.4 2.6 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG10972.1 - 1.2e-11 44.6 0.1 3.2e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_S41 PF03572.18 OAG10973.1 - 2.1e-08 33.9 0.0 8.9e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 DUF5572 PF17733.1 OAG10975.1 - 9.6e-25 86.2 0.2 1.8e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) LSM14 PF12701.7 OAG10976.1 - 1.4e-28 98.8 0.1 2.2e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OAG10976.1 - 7e-17 62.2 0.4 7e-17 62.2 0.4 2.5 3 0 0 3 3 3 1 FDF domain SM-ATX PF14438.6 OAG10976.1 - 0.00024 21.2 0.0 0.00043 20.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain VTC PF09359.10 OAG10977.1 - 5e-90 301.6 1.2 1e-89 300.6 1.2 1.5 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 OAG10977.1 - 1.9e-13 50.6 4.0 1.9e-13 50.6 4.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 OAG10977.1 - 1.2e-05 25.5 4.2 0.0003 20.8 0.2 3.7 2 1 2 4 4 4 2 SPX domain Abp2 PF09441.10 OAG10978.1 - 3.7e-83 277.7 0.0 5.5e-83 277.2 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 FA_hydroxylase PF04116.13 OAG10980.1 - 4.4e-26 91.8 26.9 1.2e-25 90.3 23.8 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily adh_short PF00106.25 OAG10984.1 - 3.4e-09 36.4 0.4 2.5e-06 27.1 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG10984.1 - 2e-06 27.5 2.6 0.0017 17.9 0.2 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SieB PF14163.6 OAG10985.1 - 0.19 11.2 1.8 0.26 10.8 1.8 1.3 1 1 0 1 1 1 0 Super-infection exclusion protein B MFS_1 PF07690.16 OAG10986.1 - 2.9e-12 46.2 7.4 3.3e-12 46.0 7.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAG10986.1 - 0.014 13.7 4.2 0.015 13.6 4.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NmrA PF05368.13 OAG10987.1 - 5.6e-26 91.5 0.0 7.1e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG10987.1 - 3.9e-12 46.4 0.0 6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG10987.1 - 0.057 12.9 0.0 0.61 9.5 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3328 PF11807.8 OAG10990.1 - 3.7e-31 108.6 0.4 4.3e-31 108.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Med26 PF08711.11 OAG10991.1 - 4.5e-10 39.4 0.0 8.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CTD_bind PF04818.13 OAG10992.1 - 3.5e-05 24.5 0.0 0.0013 19.6 0.0 2.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 OAG10992.1 - 0.00084 19.8 1.0 0.0071 16.8 1.0 2.3 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 Prok-RING_1 PF14446.6 OAG10992.1 - 0.026 14.5 0.7 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 VHS PF00790.19 OAG10992.1 - 0.2 11.5 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 VHS domain Zn-C2H2_12 PF18112.1 OAG10992.1 - 0.27 11.7 2.6 0.79 10.2 0.8 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HC_2 PF13913.6 OAG10992.1 - 0.51 10.3 3.2 10 6.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 OAG10992.1 - 2.8 7.6 6.1 4.1 7.1 1.8 2.7 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ADK PF00406.22 OAG10993.1 - 4.3e-59 199.0 0.0 5.5e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAG10993.1 - 2.5e-21 76.6 0.3 4.4e-21 75.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OAG10993.1 - 8.1e-18 64.1 0.0 1.8e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAG10993.1 - 1.4e-05 25.6 0.0 2.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG10993.1 - 0.00018 21.6 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sugarporin_N PF11471.8 OAG10993.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension AAA_24 PF13479.6 OAG10993.1 - 0.064 13.0 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 OAG10994.1 - 3e-07 30.2 0.4 3e-07 30.2 0.4 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 OAG10994.1 - 1.5e-06 27.9 0.0 4e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG10994.1 - 0.0069 16.3 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 F-box EHN PF06441.12 OAG10995.1 - 6.5e-35 119.8 0.6 1e-34 119.1 0.6 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG10995.1 - 1.7e-09 37.7 0.2 2.7e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3760 PF12586.8 OAG10996.1 - 0.0075 16.4 1.6 0.011 15.9 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3760) F-box-like PF12937.7 OAG10996.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 OAG10996.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain BTB PF00651.31 OAG10997.1 - 1.4e-08 34.9 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TMEM119 PF15724.5 OAG10997.1 - 0.0098 16.0 3.8 0.013 15.6 3.8 1.2 1 0 0 1 1 1 1 TMEM119 family Lys-AminoMut_A PF09043.11 OAG10997.1 - 0.088 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Spore_coat_CotO PF14153.6 OAG10997.1 - 0.23 11.4 5.8 0.34 10.8 5.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SDA1 PF05285.12 OAG10997.1 - 0.25 10.7 13.0 0.29 10.5 13.0 1.1 1 0 0 1 1 1 0 SDA1 TipE PF16972.5 OAG10997.1 - 1.3 8.1 6.7 1.7 7.7 6.7 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Nop14 PF04147.12 OAG10997.1 - 2.5 6.2 11.6 3.1 5.9 11.6 1.0 1 0 0 1 1 1 0 Nop14-like family NIF PF03031.18 OAG10998.1 - 4.7e-23 81.7 0.0 6.3e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 OAG10998.1 - 0.028 13.9 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) RRP36 PF06102.12 OAG10999.1 - 2e-49 167.8 36.7 2e-49 167.8 36.7 2.3 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 TrbM PF07424.11 OAG10999.1 - 0.77 9.7 4.0 1.5 8.8 3.7 1.7 1 1 0 1 1 1 0 TrbM 2OG-FeII_Oxy PF03171.20 OAG11000.1 - 7.9e-15 55.2 0.0 1.8e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG11000.1 - 2.2e-06 28.4 0.0 3.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CysA_C_terminal PF17850.1 OAG11000.1 - 0.0028 18.2 0.2 0.011 16.2 0.2 2.0 1 0 0 1 1 1 1 CysA C-terminal regulatory domain CorA PF01544.18 OAG11001.1 - 1.4e-07 31.2 3.4 4e-07 29.7 3.4 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Helo_like_N PF17111.5 OAG11001.1 - 0.0085 15.5 1.4 0.014 14.7 1.4 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF3316 PF11777.8 OAG11001.1 - 0.025 14.6 0.3 0.053 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) Takusan PF04822.13 OAG11001.1 - 0.087 12.7 0.4 0.24 11.3 0.4 1.7 1 0 0 1 1 1 0 Takusan AA_permease PF00324.21 OAG11003.1 - 1e-64 218.9 36.1 2.4e-64 217.7 36.1 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG11003.1 - 2e-20 73.1 31.0 2.6e-20 72.7 31.0 1.2 1 0 0 1 1 1 1 Amino acid permease Pectate_lyase_3 PF12708.7 OAG11005.1 - 1.3e-91 306.2 17.0 1.5e-81 273.4 6.9 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG11005.1 - 2.5e-07 30.3 2.6 0.014 15.0 0.2 3.1 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Nup54 PF13874.6 OAG11006.1 - 1.4e-35 122.5 3.6 1.4e-35 122.5 3.6 3.7 4 1 0 4 4 4 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 OAG11006.1 - 8.7e-05 22.0 6.5 0.00022 20.7 6.5 1.8 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain AvrPto PF11592.8 OAG11006.1 - 0.02 14.9 0.4 0.37 10.8 0.1 2.7 3 0 0 3 3 3 0 Central core of the bacterial effector protein AvrPto SesA PF17107.5 OAG11006.1 - 0.76 10.0 5.4 0.36 11.0 0.2 2.9 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PilJ PF13675.6 OAG11006.1 - 2.5 8.1 15.6 0.044 13.8 2.8 3.0 2 2 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ParD PF09386.10 OAG11006.1 - 9.4 6.7 10.1 1.3 9.5 0.6 3.5 3 1 1 4 4 4 0 Antitoxin ParD DUF948 PF06103.11 OAG11006.1 - 9.8 6.5 6.6 3.6 7.9 0.1 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CHCH PF06747.13 OAG11007.1 - 3.6e-07 30.1 5.1 3.6e-07 30.1 5.1 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 OAG11007.1 - 0.023 14.7 8.8 0.059 13.4 3.6 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Kre28 PF17097.5 OAG11007.1 - 0.043 12.8 0.1 0.051 12.5 0.1 1.1 1 0 0 1 1 1 0 Spindle pole body component Pet191_N PF10203.9 OAG11007.1 - 0.045 14.1 8.9 0.59 10.5 2.2 2.9 2 1 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 OAG11007.1 - 0.083 13.1 10.6 1.5 9.1 10.6 2.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.17 OAG11007.1 - 1.7 9.0 11.7 2.7 8.3 0.7 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 OAG11007.1 - 5.4 7.1 14.1 3.4 7.8 4.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Apc15p PF05841.11 OAG11009.1 - 1.9e-10 41.6 0.4 1.9e-10 41.6 0.4 2.6 2 1 1 3 3 3 1 Apc15p protein TAF4 PF05236.14 OAG11009.1 - 0.017 14.9 5.4 0.037 13.8 5.4 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family adh_short PF00106.25 OAG11010.1 - 4.7e-23 81.7 0.7 1.7e-19 70.1 0.8 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG11010.1 - 6.8e-14 52.0 0.2 1.8e-12 47.4 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG11010.1 - 5.7e-05 23.1 0.3 0.00017 21.6 0.1 1.7 1 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG11010.1 - 0.00059 19.4 0.1 0.00082 18.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 OAG11011.1 - 3.9e-41 141.2 0.0 5.2e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11011.1 - 2.2e-30 105.8 0.0 3.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAG11011.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RICH PF05062.12 OAG11011.1 - 0.39 11.1 1.0 0.69 10.3 0.2 1.7 2 0 0 2 2 2 0 RICH domain TPR_10 PF13374.6 OAG11012.1 - 5.3e-63 207.3 22.2 5.1e-08 32.5 0.1 8.1 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 OAG11012.1 - 7.1e-43 144.8 37.8 4.4e-10 39.7 2.8 5.7 1 1 3 6 6 6 6 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG11012.1 - 5.2e-31 106.7 21.4 3.6e-07 30.3 0.7 8.0 1 1 7 8 8 8 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAG11012.1 - 2.2e-24 83.5 24.9 0.0023 17.9 0.5 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 OAG11012.1 - 5.4e-19 68.6 12.3 0.0024 18.5 0.4 7.0 4 2 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG11012.1 - 7.8e-18 63.5 21.7 0.025 14.4 0.3 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 OAG11012.1 - 4.9e-17 61.4 20.0 0.12 13.0 0.2 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAG11012.1 - 7.6e-13 48.8 15.4 0.011 16.3 0.1 6.3 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_3 PF07720.12 OAG11012.1 - 8e-11 41.7 24.1 0.094 12.7 1.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG11012.1 - 1.5e-10 40.5 24.3 0.098 12.9 0.7 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat YfdX PF10938.8 OAG11012.1 - 8.4e-08 32.3 5.7 3.4 7.6 0.0 6.9 8 0 0 8 8 8 2 YfdX protein TPR_14 PF13428.6 OAG11012.1 - 1.4e-06 28.6 9.8 18 6.5 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG11012.1 - 2.8e-06 26.9 21.1 0.00082 18.8 4.3 3.6 1 1 2 3 3 3 3 MalT-like TPR region DUF4807 PF16065.5 OAG11012.1 - 3.9e-06 26.5 8.8 0.55 9.9 0.0 5.8 3 2 3 6 6 6 2 Domain of unknown function (DUF4807) PPR PF01535.20 OAG11012.1 - 4.1e-06 26.7 3.6 4.4 7.8 0.0 7.1 8 0 0 8 8 8 1 PPR repeat TPR_7 PF13176.6 OAG11012.1 - 5.8e-06 26.0 24.2 0.99 9.6 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG11012.1 - 7.8e-06 25.5 32.9 0.19 11.5 0.2 7.9 9 0 0 9 9 8 4 TPR repeat LAL_C2 PF18603.1 OAG11012.1 - 1.3e-05 25.2 0.0 0.29 11.3 0.0 5.4 7 0 0 7 7 6 1 L-amino acid ligase C-terminal domain 2 Fis1_TPR_C PF14853.6 OAG11012.1 - 3.6e-05 23.7 7.6 1.4 9.1 0.3 6.1 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.9 OAG11012.1 - 3.7e-05 23.7 10.8 0.073 13.2 0.1 5.3 5 2 1 6 6 5 1 Rapsyn N-terminal myristoylation and linker region GGDEF PF00990.21 OAG11012.1 - 0.00013 21.8 2.0 0.55 10.0 0.1 4.0 2 2 2 5 5 5 2 Diguanylate cyclase, GGDEF domain TPR_4 PF07721.14 OAG11012.1 - 0.00018 21.8 0.0 73 4.4 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF2063 PF09836.9 OAG11012.1 - 0.0031 17.7 4.0 7.1 6.9 0.0 4.0 2 2 1 4 4 4 0 Putative DNA-binding domain DUF4715 PF15835.5 OAG11012.1 - 0.012 15.7 7.2 8.5 6.4 0.3 4.3 1 1 3 5 5 5 0 Domain of unknown function (DUF4715) PMEI PF04043.15 OAG11012.1 - 0.039 14.3 0.5 2.3 8.5 0.1 2.5 2 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor SRP_TPR_like PF17004.5 OAG11012.1 - 0.042 13.9 20.1 21 5.2 0.1 5.8 1 1 3 5 5 5 0 Putative TPR-like repeat IDH PF03971.14 OAG11012.1 - 0.095 11.1 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase ParD_antitoxin PF03693.14 OAG11012.1 - 0.23 11.9 1.7 18 5.8 0.0 3.7 4 0 0 4 4 4 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH PPR_1 PF12854.7 OAG11012.1 - 0.38 10.5 4.1 9.8 6.0 0.0 4.3 7 0 0 7 7 6 0 PPR repeat FeoB_Cyto PF17910.1 OAG11012.1 - 0.82 10.3 9.2 9.5 6.8 0.0 4.7 5 1 0 5 5 5 0 FeoB cytosolic helical domain PRA-PH PF01503.17 OAG11012.1 - 2.9 8.4 8.5 0.51 10.8 0.5 3.5 1 1 3 4 4 4 0 Phosphoribosyl-ATP pyrophosphohydrolase TPR_17 PF13431.6 OAG11012.1 - 6 7.5 16.1 16 6.2 0.1 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat P53_tetramer PF07710.11 OAG11012.1 - 6.9 6.1 13.3 18 4.7 0.0 4.8 6 0 0 6 6 5 0 P53 tetramerisation motif Tubulin PF00091.25 OAG11013.1 - 1e-66 224.9 0.0 1.5e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG11013.1 - 3.7e-49 166.1 0.1 6.6e-49 165.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAG11013.1 - 0.0017 18.1 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.9 OAG11014.1 - 1.2e-05 25.3 0.1 4.2e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator SbmA_BacA PF05992.12 OAG11014.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 SbmA/BacA-like family COX4 PF02936.14 OAG11016.1 - 5.3e-40 136.6 0.2 7.6e-40 136.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 OAG11016.1 - 0.31 11.5 8.4 0.068 13.6 3.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1289 PF06945.13 OAG11016.1 - 6.3 6.7 5.4 14 5.6 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) Gp_dh_C PF02800.20 OAG11017.1 - 2.6e-72 241.6 0.1 3.7e-72 241.1 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OAG11017.1 - 6.7e-39 132.3 0.1 1.4e-38 131.2 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG11017.1 - 0.015 15.4 0.0 0.062 13.4 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 OAG11017.1 - 0.087 12.2 0.1 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltr_RsmF_N PF17125.5 OAG11017.1 - 0.21 12.1 0.0 0.44 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Hist_deacetyl PF00850.19 OAG11018.1 - 1.1e-86 291.1 0.0 1.7e-86 290.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 OAG11018.1 - 7.4e-85 284.2 0.1 1e-84 283.7 0.1 1.2 1 0 0 1 1 1 1 Arb2 domain H_PPase PF03030.16 OAG11019.1 - 0.12 10.9 0.2 0.17 10.5 0.2 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Cyclin PF08613.11 OAG11021.1 - 7.8e-31 107.6 0.0 1.2e-30 107.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG11021.1 - 8.3e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1891 PF09004.10 OAG11021.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Arm PF00514.23 OAG11024.1 - 2.8e-15 55.8 7.6 0.00023 21.1 0.0 9.5 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAG11024.1 - 0.0024 18.4 9.1 2.6 8.7 0.1 6.8 8 0 0 8 8 8 1 HEAT-like repeat IFRD PF05004.13 OAG11024.1 - 0.0029 16.7 0.8 0.032 13.4 0.0 2.7 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) MethyTransf_Reg PF10119.9 OAG11024.1 - 0.13 13.0 0.1 0.61 10.8 0.1 2.2 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain CLASP_N PF12348.8 OAG11024.1 - 0.13 11.8 0.0 5.1 6.6 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal HEAT PF02985.22 OAG11024.1 - 0.27 11.6 13.7 30 5.2 0.0 7.0 7 0 0 7 7 7 0 HEAT repeat FA_desaturase PF00487.24 OAG11025.1 - 3.3e-23 82.8 20.7 7.1e-23 81.7 20.7 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OAG11025.1 - 2.2e-06 27.9 0.0 8.6e-06 26.0 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3474) Na_H_Exchanger PF00999.21 OAG11026.1 - 7.7e-49 166.5 15.2 9.8e-49 166.1 15.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LtrA PF06772.11 OAG11027.1 - 3e-44 151.7 27.8 4.2e-44 151.2 27.8 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) baeRF_family3 PF18845.1 OAG11027.1 - 0.0011 19.2 1.6 0.0043 17.3 1.6 1.9 1 1 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 UPF0767 PF15990.5 OAG11027.1 - 0.27 11.4 0.8 0.58 10.3 0.1 1.9 2 0 0 2 2 2 0 UPF0767 family DUF3287 PF11690.8 OAG11027.1 - 0.6 9.8 7.6 0.036 13.8 1.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) TPPK_C PF12555.8 OAG11029.1 - 0.042 13.9 0.4 0.095 12.8 0.4 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal FMN_dh PF01070.18 OAG11030.1 - 2.2e-107 359.1 0.1 2.6e-107 358.9 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG11030.1 - 9.7e-20 70.5 0.0 2.4e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG11030.1 - 3.6e-07 29.6 0.1 5.7e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG11030.1 - 1.3e-06 27.6 0.2 0.00025 20.2 0.1 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG11030.1 - 0.0055 16.1 0.2 0.0086 15.5 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAG11030.1 - 0.016 14.7 0.0 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 OAG11030.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF3402 PF11882.8 OAG11031.1 - 8.3e-186 618.6 0.0 1e-185 618.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 OAG11031.1 - 1.5e-84 283.6 0.0 2.2e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein HLH PF00010.26 OAG11032.1 - 9e-13 48.0 0.5 1.6e-12 47.1 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.12 OAG11032.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein RNA_pol_Rpb2_6 PF00562.28 OAG11034.1 - 3.3e-121 405.0 0.1 5.8e-121 404.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG11034.1 - 2.6e-50 170.8 0.3 4e-50 170.1 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 OAG11034.1 - 1.4e-33 115.1 0.7 5.2e-33 113.3 0.7 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OAG11034.1 - 5.5e-29 101.2 0.7 1.4e-28 99.9 0.6 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 OAG11034.1 - 1.3e-22 79.8 0.1 3.3e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OAG11034.1 - 2.9e-18 65.8 0.0 7.6e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAG11034.1 - 9.9e-09 35.6 3.0 1.1e-08 35.5 0.9 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 5 RecR PF02132.15 OAG11034.1 - 0.046 13.3 1.4 0.11 12.1 1.4 1.6 1 0 0 1 1 1 0 RecR protein DUF3915 PF13054.6 OAG11035.1 - 8.7 6.3 5.2 22 5.1 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF382 PF04037.13 OAG11036.1 - 1.9e-56 189.6 0.4 1.9e-56 189.6 0.4 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 OAG11036.1 - 3.2e-21 74.9 2.9 6.5e-21 73.9 2.9 1.6 1 0 0 1 1 1 1 PSP Aldo_ket_red PF00248.21 OAG11037.1 - 2.1e-48 165.1 0.1 5e-47 160.5 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family E1-E2_ATPase PF00122.20 OAG11038.1 - 2e-48 164.3 5.4 2e-48 164.3 5.4 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 OAG11038.1 - 1.1e-14 55.3 4.4 2.3e-14 54.2 0.7 3.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG11038.1 - 8.8e-09 34.9 0.0 2.1e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG11038.1 - 0.0024 17.7 0.1 0.0048 16.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG11038.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2818 PF10993.8 OAG11038.1 - 0.37 11.4 3.5 0.27 11.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) TPR_10 PF13374.6 OAG11040.1 - 3.8e-94 306.3 32.3 1.1e-13 50.5 0.1 11.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.6 OAG11040.1 - 3.2e-70 232.4 42.8 3.2e-19 69.0 2.2 8.9 2 1 4 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.6 OAG11040.1 - 4.9e-21 73.2 25.7 0.002 18.0 0.1 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG11040.1 - 2.2e-18 65.2 25.3 0.077 12.9 0.0 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 OAG11040.1 - 1.1e-11 44.0 12.2 0.6 10.5 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat HET PF06985.11 OAG11040.1 - 1.8e-09 38.1 7.2 4.3e-08 33.6 1.3 2.9 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 OAG11040.1 - 6.1e-09 35.4 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 OAG11040.1 - 4.7e-08 33.2 33.2 0.039 14.8 0.2 9.7 9 3 2 11 11 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG11040.1 - 8e-08 31.8 27.5 2 8.8 0.1 10.3 9 1 0 9 9 9 1 Tetratricopeptide repeat AAA_16 PF13191.6 OAG11040.1 - 2e-06 28.3 0.3 8.1e-06 26.3 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 OAG11040.1 - 4.4e-06 26.7 0.2 2.1 8.9 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG11040.1 - 1.3e-05 25.8 20.8 1.5 9.5 0.6 8.2 5 3 2 7 7 7 1 Tetratricopeptide repeat NACHT PF05729.12 OAG11040.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 OAG11040.1 - 0.00019 21.9 16.4 0.64 10.6 0.1 7.0 3 2 5 9 9 8 3 Tetratricopeptide repeat ATPase_2 PF01637.18 OAG11040.1 - 0.00035 20.6 0.0 0.00093 19.2 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAG11040.1 - 0.00056 20.2 0.0 0.0023 18.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain ANAPC3 PF12895.7 OAG11040.1 - 0.0023 18.1 4.4 2.5 8.4 0.0 5.2 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 ResIII PF04851.15 OAG11040.1 - 0.01 15.8 0.0 0.04 13.9 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TPR_4 PF07721.14 OAG11040.1 - 0.021 15.4 10.1 0.84 10.4 0.0 6.2 6 0 0 6 6 4 0 Tetratricopeptide repeat ATPase PF06745.13 OAG11040.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC ATP-synt_ab PF00006.25 OAG11042.1 - 4.5e-62 209.5 0.0 7.4e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAG11042.1 - 6.4e-23 81.1 0.4 2.4e-22 79.2 0.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 OAG11042.1 - 0.0029 18.0 0.0 0.15 12.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OAG11042.1 - 0.012 14.8 0.3 0.06 12.5 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 OAG11042.1 - 0.014 15.3 0.7 0.03 14.2 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 OAG11042.1 - 0.038 14.3 0.8 0.48 10.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain T3SS_ATPase_C PF18269.1 OAG11042.1 - 0.05 13.5 0.6 0.27 11.1 0.6 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NACHT PF05729.12 OAG11042.1 - 0.051 13.5 0.2 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 OAG11042.1 - 0.062 12.6 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OAG11042.1 - 0.072 13.5 0.4 0.25 11.7 0.2 2.0 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 OAG11042.1 - 0.076 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 OAG11042.1 - 0.26 10.7 0.1 0.51 9.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Molybdopterin PF00384.22 OAG11043.1 - 6.8e-70 236.2 0.0 2.7e-34 118.9 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 OAG11043.1 - 5.9e-20 71.1 0.2 1.8e-19 69.6 0.2 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 OAG11043.1 - 2.9e-19 69.5 0.0 7.1e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 OAG11043.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 OAG11043.1 - 5.4e-08 32.7 0.6 5.4e-08 32.7 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 OAG11043.1 - 0.023 14.4 0.0 0.84 9.4 0.0 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF2012 PF09430.10 OAG11044.1 - 8.6e-27 93.7 0.0 1.2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 OAG11044.1 - 2.3e-06 27.3 0.1 0.037 13.5 0.0 2.2 2 0 0 2 2 2 2 Suppressor of PMA 1-7 protein MIP PF00230.20 OAG11045.1 - 2.3e-47 161.6 12.0 2.9e-47 161.3 12.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3493 PF11998.8 OAG11045.1 - 5.1 7.3 6.7 6 7.1 0.4 3.2 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 DUF2955 PF11168.8 OAG11045.1 - 5.9 6.7 12.7 0.16 11.8 5.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2955) NUDIX PF00293.28 OAG11046.1 - 1.4e-09 38.1 0.0 2.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain AICARFT_IMPCHas PF01808.18 OAG11047.1 - 2e-93 313.1 0.0 2.7e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OAG11047.1 - 2.2e-24 85.4 0.0 4.3e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Dis3l2_C_term PF17877.1 OAG11047.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal XPC-binding PF09280.11 OAG11048.1 - 1.2e-24 85.8 15.8 1.9e-24 85.1 15.8 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 OAG11048.1 - 4.1e-21 74.5 0.1 6.3e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OAG11048.1 - 3.9e-20 71.4 6.9 6.8e-13 48.2 0.5 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 OAG11048.1 - 3.1e-07 30.1 0.6 5.1e-07 29.4 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAG11048.1 - 0.0039 17.3 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 OAG11048.1 - 0.0059 16.4 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 OAG11048.1 - 0.037 14.4 0.2 0.064 13.6 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 OAG11048.1 - 0.073 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WIYLD PF10440.9 OAG11048.1 - 0.076 12.8 0.3 1.1 9.1 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Clathrin_H_link PF13838.6 OAG11048.1 - 0.1 12.5 0.8 0.42 10.5 0.2 2.4 2 0 0 2 2 2 0 Clathrin-H-link CD99L2 PF12301.8 OAG11048.1 - 0.11 12.8 1.2 0.22 11.8 1.2 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 MCM_N PF14551.6 OAG11048.1 - 0.12 13.0 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 MCM N-terminal domain Bacteriocin_IId PF09221.10 OAG11049.1 - 1.3 9.2 12.7 5.1 7.4 6.2 2.4 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Sds3 PF08598.11 OAG11051.1 - 0.0046 17.0 5.1 0.0046 17.0 5.1 2.5 2 1 0 2 2 2 1 Sds3-like Es2 PF09751.9 OAG11052.1 - 1.3e-115 387.7 5.4 1.5e-115 387.4 5.4 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 eIF-6 PF01912.18 OAG11053.1 - 2.9e-80 268.3 1.6 3.7e-80 268.0 1.6 1.1 1 0 0 1 1 1 1 eIF-6 family CPBP PF02517.16 OAG11055.1 - 2.1e-15 56.9 8.9 2.1e-15 56.9 8.9 3.0 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease UCH PF00443.29 OAG11056.1 - 1.9e-32 112.7 0.0 5.2e-32 111.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG11056.1 - 1.1e-11 44.9 0.2 1.6e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Eapp_C PF10238.9 OAG11056.1 - 0.19 11.8 2.7 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Methyltransf_11 PF08241.12 OAG11057.1 - 1.9e-12 47.7 0.0 3.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG11057.1 - 7.9e-11 42.5 0.0 1.8e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG11057.1 - 5.2e-08 32.9 0.0 4e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG11057.1 - 6.5e-06 26.8 0.1 1.8e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG11057.1 - 7e-06 25.9 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG11057.1 - 0.017 14.0 1.0 0.096 11.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 OAG11057.1 - 0.053 13.4 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase DnaB_bind PF10410.9 OAG11057.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase LYTB PF02401.18 OAG11057.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 LytB protein GCP_N_terminal PF17681.1 OAG11058.1 - 1.5e-63 215.3 0.4 4.5e-63 213.7 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAG11058.1 - 2.6e-58 197.9 1.0 3.5e-58 197.5 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal NARP1 PF12569.8 OAG11058.1 - 0.15 10.9 0.4 0.41 9.5 0.0 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Choline_transpo PF04515.12 OAG11059.1 - 2e-25 89.7 19.5 2e-25 89.7 19.5 2.6 1 1 2 3 3 3 1 Plasma-membrane choline transporter Ras PF00071.22 OAG11060.1 - 2.1e-48 164.0 0.1 2.4e-47 160.5 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG11060.1 - 3.6e-28 98.2 0.0 6.7e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG11060.1 - 1.1e-10 41.3 0.0 9.1e-10 38.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG11060.1 - 1.3e-07 31.4 0.0 4.9e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG11060.1 - 4.1e-05 23.1 0.0 6.7e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG11060.1 - 0.00047 20.2 0.0 0.0022 18.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG11060.1 - 0.016 15.1 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OAG11060.1 - 0.033 13.9 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Flu_M1_C PF08289.11 OAG11060.1 - 0.16 12.2 0.3 0.28 11.4 0.3 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain HET PF06985.11 OAG11062.1 - 3.7e-23 82.5 0.0 5.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhoLip_ATPase_C PF16212.5 OAG11063.1 - 3e-54 184.4 5.8 3e-54 184.4 5.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG11063.1 - 2e-16 59.4 0.1 4.2e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAG11063.1 - 1.4e-13 51.6 0.6 2.2e-05 24.8 0.1 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAG11063.1 - 3.9e-08 33.0 0.1 3.3e-07 30.0 0.1 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAG11063.1 - 2e-06 27.8 0.0 3.9e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG11063.1 - 0.0025 17.6 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec16_C PF12931.7 OAG11064.1 - 3.7e-107 358.5 0.0 5.1e-107 358.0 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OAG11064.1 - 6.8e-35 120.2 1.3 7.1e-34 116.9 0.0 2.8 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region PUF PF00806.19 OAG11068.1 - 4.5e-62 202.4 11.7 9.5e-09 34.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Tk-SP_N-pro PF18237.1 OAG11069.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Tk-SP N-propeptide domain HOOK PF05622.12 OAG11070.1 - 1e-12 47.1 87.8 7.8e-12 44.2 87.8 3.3 1 1 0 1 1 1 1 HOOK protein Fib_alpha PF08702.10 OAG11070.1 - 0.0034 17.6 3.6 0.0034 17.6 3.6 5.4 2 1 2 5 5 5 1 Fibrinogen alpha/beta chain family SLED PF12140.8 OAG11070.1 - 0.004 17.6 1.0 0.042 14.4 0.0 3.0 2 1 0 2 2 2 1 SLED domain YqgF PF14639.6 OAG11070.1 - 0.33 10.7 5.9 1.1 9.1 5.9 1.9 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 MukB PF04310.12 OAG11070.1 - 0.51 10.1 12.2 0.87 9.4 2.5 2.8 2 0 0 2 2 2 0 MukB N-terminal ParE_toxin PF05016.15 OAG11070.1 - 6.7 7.4 8.3 4.9 7.8 2.8 3.3 1 1 1 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE PMT PF02366.18 OAG11073.1 - 4.6e-90 301.5 15.9 4.6e-90 301.5 15.9 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAG11073.1 - 2.3e-67 226.5 12.3 2.3e-67 226.5 12.3 2.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAG11073.1 - 6.2e-35 120.7 2.1 9.4e-35 120.1 2.1 1.1 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.24 OAG11075.1 - 3e-106 356.0 16.2 3.7e-106 355.7 16.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG11075.1 - 8.9e-29 100.5 53.5 1.9e-25 89.6 26.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG11075.1 - 1.3e-07 30.5 20.2 1.1e-05 24.3 5.3 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAG11075.1 - 0.0074 15.2 6.1 0.34 9.7 4.8 2.3 1 1 1 2 2 2 2 MFS_1 like family TRI12 PF06609.13 OAG11075.1 - 1.9 6.8 9.4 0.04 12.3 2.1 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Chs7 PF12271.8 OAG11076.1 - 4.4e-106 354.5 9.7 5.3e-106 354.2 9.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone EAGR_box PF16713.5 OAG11076.1 - 1.4 8.6 3.7 2.3 7.9 0.2 2.3 2 0 0 2 2 2 0 Enriched in aromatic and glycine Residues box DUF1218 PF06749.12 OAG11076.1 - 7.4 7.2 10.0 11 6.6 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) FAA_hydrolase PF01557.18 OAG11077.1 - 2.3e-63 213.8 0.0 4.2e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ssl1 PF04056.14 OAG11077.1 - 1.1e-25 90.6 0.0 4.9e-15 55.8 0.0 2.4 2 0 0 2 2 2 2 Ssl1-like C1_4 PF07975.12 OAG11077.1 - 5.3e-15 55.4 7.6 5.3e-15 55.4 7.6 3.3 3 1 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 OAG11077.1 - 9.2e-06 26.3 0.0 3.1e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-HIT PF04438.16 OAG11077.1 - 0.53 10.2 20.2 0.035 14.0 5.2 3.4 3 0 0 3 3 3 0 HIT zinc finger Tfb4 PF03850.14 OAG11077.1 - 1.4 8.3 5.3 3.7 6.9 5.3 1.7 1 0 0 1 1 1 0 Transcription factor Tfb4 DZR PF12773.7 OAG11077.1 - 9.3 6.4 21.5 1.3 9.1 6.3 2.9 2 1 0 2 2 2 0 Double zinc ribbon CAP_GLY PF01302.25 OAG11079.1 - 3.6e-25 87.7 0.2 5.2e-25 87.3 0.2 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OAG11079.1 - 1.4e-20 73.5 0.0 2.2e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 OAG11079.1 - 0.00013 21.7 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.31 OAG11080.1 - 4.3e-14 52.4 4.3 6.9e-11 42.2 0.0 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG11080.1 - 3.1e-06 27.3 3.7 0.0026 18.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 OAG11080.1 - 0.17 11.1 0.1 0.26 10.6 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Mif2_N PF15624.6 OAG11083.1 - 1.3e-40 139.2 4.4 1.3e-40 139.2 4.4 2.9 2 1 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 OAG11083.1 - 1.6e-14 53.8 0.0 3.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Isochorismatase PF00857.20 OAG11084.1 - 1.9e-22 80.3 0.0 3.5e-22 79.4 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family p450 PF00067.22 OAG11085.1 - 9.2e-34 117.0 0.0 1.4e-22 80.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 CRT10 PF08728.10 OAG11086.1 - 1.2e-15 56.8 0.0 7.7e-09 34.3 0.0 2.2 2 0 0 2 2 2 2 CRT10 WD40 PF00400.32 OAG11086.1 - 0.0005 20.8 4.8 0.41 11.6 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Mito_carr PF00153.27 OAG11088.1 - 2.4e-27 94.7 4.1 1.3e-11 44.3 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 OAG11089.1 - 2.7e-102 342.6 0.0 3.3e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 OAG11089.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone Not3 PF04065.15 OAG11089.1 - 0.9 8.9 3.2 7.6 5.9 0.1 2.4 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component CTD_bind PF04818.13 OAG11090.1 - 1.1e-08 35.7 0.0 2.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 OAG11090.1 - 7e-08 32.2 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lysine_decarbox PF03641.14 OAG11091.1 - 9.1e-29 100.2 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAG11091.1 - 3.3e-05 23.5 0.4 6.2e-05 22.6 0.4 1.5 1 1 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 OAG11091.1 - 0.052 12.8 0.1 0.072 12.3 0.1 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote CLPTM1 PF05602.12 OAG11092.1 - 4.8e-158 526.7 0.3 5.8e-158 526.4 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Abhydrolase_6 PF12697.7 OAG11093.1 - 1.7e-08 35.3 0.1 2e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 OAG11093.1 - 4.4e-05 23.2 0.3 0.0029 17.3 0.1 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase Pectinesterase PF01095.19 OAG11094.1 - 2.3e-46 157.9 7.8 3e-46 157.5 7.8 1.1 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.17 OAG11095.1 - 2.3e-46 158.3 14.7 2.9e-46 158.0 14.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_49 PF03718.13 OAG11095.1 - 0.027 14.5 0.3 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 End_N_terminal PF12218.8 OAG11095.1 - 0.053 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Peptidase_M43 PF05572.13 OAG11095.1 - 0.11 12.4 1.6 0.26 11.2 0.3 2.1 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A SBDS PF01172.18 OAG11096.1 - 2.1e-20 72.6 0.1 2.5e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SLT_beta PF02258.16 OAG11096.1 - 0.057 13.5 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Shiga-like toxin beta subunit AA_permease PF00324.21 OAG11097.1 - 2.5e-125 418.8 44.5 3e-125 418.5 44.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG11097.1 - 3.9e-37 128.1 48.1 5.3e-37 127.7 48.1 1.1 1 0 0 1 1 1 1 Amino acid permease CDH PF02611.15 OAG11098.1 - 0.00035 20.3 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase DUF620 PF04788.12 OAG11098.1 - 0.059 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF620) Tyrosinase PF00264.20 OAG11099.1 - 5.3e-19 69.4 0.5 2.2e-10 41.2 1.9 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase Helicase_C PF00271.31 OAG11100.1 - 9.9e-09 35.5 0.0 1.6e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Patatin PF01734.22 OAG11103.1 - 2.1e-20 73.8 0.0 5.2e-20 72.5 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3734 PF12536.8 OAG11103.1 - 0.065 13.6 0.3 22 5.5 0.0 2.6 3 0 0 3 3 3 0 Patatin phospholipase DUF900 PF05990.12 OAG11105.1 - 0.0027 17.3 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 OAG11105.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 OAG11105.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 OAG11105.1 - 0.021 14.5 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 OAG11105.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 OAG11105.1 - 0.16 11.8 0.0 2.4 8.0 0.0 2.2 1 1 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.13 OAG11105.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase Endosulfine PF04667.17 OAG11106.1 - 1.8e-12 47.2 0.2 4.1e-12 46.1 0.2 1.7 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region TFIID_20kDa PF03847.13 OAG11107.1 - 0.0097 16.4 0.1 7.8 7.1 0.0 3.5 3 0 0 3 3 3 1 Transcription initiation factor TFIID subunit A BLOC1S3 PF15753.5 OAG11107.1 - 0.052 13.7 0.3 0.14 12.3 0.2 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 PRP1_N PF06424.12 OAG11108.1 - 0.58 10.6 3.2 0.41 11.1 0.1 2.2 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal Sec34 PF04136.15 OAG11108.1 - 0.63 9.9 3.9 1.1 9.1 3.9 1.3 1 0 0 1 1 1 0 Sec34-like family IBV_3A PF03617.13 OAG11109.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 IBV 3A protein DUF3040 PF11239.8 OAG11109.1 - 0.14 12.5 1.4 4.2 7.7 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) RP-C_C PF11800.8 OAG11109.1 - 0.35 10.9 3.7 0.56 10.3 3.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region ERM PF00769.19 OAG11111.1 - 0.19 11.5 12.0 0.27 11.0 12.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 OAG11111.1 - 0.4 10.0 13.5 2.4 7.4 13.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.8 OAG11111.1 - 1.1 9.3 15.0 2.4 8.2 3.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 OAG11111.1 - 1.2 8.9 12.3 1.7 8.5 1.9 2.9 2 1 1 3 3 3 0 Septum formation initiator Csm1_N PF18504.1 OAG11111.1 - 3 8.2 14.7 0.25 11.7 2.3 3.5 2 2 1 3 3 3 0 Csm1 N-terminal domain YabA PF06156.13 OAG11111.1 - 5.1 7.8 8.1 2.7 8.7 4.6 2.2 2 1 1 3 3 3 0 Initiation control protein YabA CENP-H PF05837.12 OAG11111.1 - 6.1 7.3 13.0 2.4 8.6 6.8 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2205 PF10224.9 OAG11111.1 - 6.2 6.9 9.4 6.7 6.8 0.9 2.5 2 0 0 2 2 2 0 Short coiled-coil protein Fez1 PF06818.15 OAG11111.1 - 8.5 6.8 14.4 65 3.9 14.4 2.0 1 1 0 1 1 1 0 Fez1 Jnk-SapK_ap_N PF09744.9 OAG11111.1 - 9.2 6.5 15.1 3.6 7.8 11.9 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DnaJ PF00226.31 OAG11114.1 - 0.026 14.6 0.0 0.067 13.3 0.0 1.7 2 0 0 2 2 2 0 DnaJ domain DUF1515 PF07439.11 OAG11115.1 - 0.04 13.9 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Chi-conotoxin PF16981.5 OAG11115.1 - 0.2 11.9 0.1 0.64 10.3 0.1 1.9 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily COG6 PF06419.11 OAG11115.1 - 0.23 9.6 0.0 0.32 9.2 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Kinesin PF00225.23 OAG11116.1 - 2.6e-20 72.6 0.0 3.6e-19 68.9 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG11116.1 - 6.2e-10 39.2 0.0 9.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding DUF688 PF05097.12 OAG11120.1 - 0.084 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) AA_permease PF00324.21 OAG11121.1 - 1.9e-14 53.2 6.0 1.9e-14 53.1 6.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG11121.1 - 1.4e-05 24.2 8.7 1.5e-05 24.0 8.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3323 PF11796.8 OAG11123.1 - 0.0085 16.0 2.3 0.0085 16.0 2.3 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminus (DUF3323) Methyltransf_16 PF10294.9 OAG11125.1 - 8.4e-17 61.4 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG11125.1 - 0.027 14.3 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CSN8_PSD8_EIF3K PF10075.9 OAG11126.1 - 6.2e-40 136.5 0.0 8.7e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Ank_2 PF12796.7 OAG11127.1 - 0.00035 21.1 0.0 0.00041 20.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG11127.1 - 0.00049 20.6 0.0 0.098 13.3 0.0 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG11127.1 - 0.036 14.6 0.0 0.33 11.7 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeat DIOX_N PF14226.6 OAG11128.1 - 1.3e-27 96.9 0.1 2.2e-27 96.2 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG11128.1 - 1.3e-14 54.5 0.0 2.1e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG11129.1 - 8.8e-33 113.7 22.4 1.3e-32 113.1 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.22 OAG11130.1 - 2.7e-37 128.0 0.0 3.2e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 OAG11130.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 PA domain Fungal_trans PF04082.18 OAG11131.1 - 5.2e-24 84.7 0.7 9.1e-24 83.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11132.1 - 0.0096 16.0 2.1 0.017 15.2 2.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 OAG11132.1 - 0.019 15.0 3.1 0.019 15.0 3.1 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 OAG11133.1 - 4.7e-22 78.4 40.9 2.7e-16 59.5 40.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily CorA PF01544.18 OAG11135.1 - 0.00015 21.2 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 OAG11135.1 - 0.07 11.9 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DnaJ PF00226.31 OAG11136.1 - 9e-22 77.0 1.7 9e-22 77.0 1.7 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 OAG11136.1 - 2.9e-19 67.6 10.7 0.00028 20.8 0.0 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG11136.1 - 1.8e-15 56.0 11.2 8.3e-06 25.4 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG11136.1 - 2.4e-12 46.8 4.8 0.00024 21.2 0.0 5.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAG11136.1 - 1.2e-10 41.7 10.0 0.00032 21.1 0.9 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG11136.1 - 5.3e-09 36.2 9.8 0.66 11.0 0.0 7.0 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG11136.1 - 8.1e-09 35.0 8.9 0.0079 16.3 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG11136.1 - 1.2e-07 31.6 0.9 0.0051 17.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG11136.1 - 2.1e-05 24.9 15.9 1.7 9.5 0.0 7.5 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG11136.1 - 0.00015 22.3 12.6 0.5 11.1 5.6 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG11136.1 - 0.00042 20.5 8.4 0.031 14.5 0.1 4.7 5 1 1 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OAG11136.1 - 0.00059 20.1 12.3 0.098 13.0 0.1 6.0 4 2 2 6 6 6 1 Tetratricopeptide repeat PknG_TPR PF16918.5 OAG11136.1 - 0.00078 18.3 0.9 0.0075 15.0 0.2 2.4 2 1 0 2 2 2 1 Protein kinase G tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG11136.1 - 0.0026 17.8 1.6 6.3 7.0 0.1 3.8 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 OAG11136.1 - 0.0052 16.7 4.6 9.3 6.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ArnB_C PF18677.1 OAG11136.1 - 0.0087 16.1 1.1 0.0087 16.1 1.1 2.0 2 0 0 2 2 1 1 Archaellum regulatory network B, C-terminal domain BORCS8 PF10167.9 OAG11136.1 - 0.01 15.7 1.0 0.087 12.8 0.2 2.4 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 TPR_11 PF13414.6 OAG11136.1 - 0.019 14.6 5.6 0.23 11.2 0.0 5.0 5 1 1 6 6 6 0 TPR repeat Transcrip_act PF04949.13 OAG11136.1 - 0.025 14.5 1.4 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 Transcriptional activator SesA PF17107.5 OAG11136.1 - 0.11 12.7 2.4 0.8 9.9 0.5 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Alkyl_sulf_dimr PF14863.6 OAG11136.1 - 1 9.8 4.5 37 4.8 0.2 3.5 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 OAG11136.1 - 4.4 7.3 10.8 14 5.7 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 OAG11137.1 - 1.7e-20 73.3 0.1 4.9e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAG11137.1 - 1.1e-12 48.0 3.6 9.1e-10 38.4 2.7 3.0 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.12 OAG11138.1 - 6.9e-12 45.7 6.8 3.5e-08 33.6 0.0 4.0 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 OAG11138.1 - 1.3e-05 25.0 0.5 0.00015 21.6 0.0 3.1 3 1 1 4 4 4 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.14 OAG11138.1 - 0.013 14.8 0.1 0.27 10.5 0.0 3.1 3 1 0 3 3 3 0 V-ATPase subunit H DUF2013 PF09431.10 OAG11139.1 - 1.8e-50 170.7 0.2 4.8e-50 169.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) MFS_5 PF05631.14 OAG11140.1 - 5.2e-61 206.5 7.0 1.2e-60 205.3 7.0 1.5 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OAG11140.1 - 3.8e-25 88.6 18.4 6.4e-25 87.8 18.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG11140.1 - 1.6e-08 33.8 0.0 0.0087 15.0 0.0 3.0 2 1 1 3 3 3 3 MFS_1 like family Methyltransf_22 PF13383.6 OAG11141.1 - 1.6e-15 57.4 0.0 2.4e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OAG11141.1 - 4.1e-06 26.9 0.0 5.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Piwi PF02171.17 OAG11142.1 - 8.4e-43 146.7 0.2 1e-42 146.5 0.2 1.0 1 0 0 1 1 1 1 Piwi domain Peptidase_S13 PF02113.15 OAG11142.1 - 0.02 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family GFA PF04828.14 OAG11143.1 - 8.8e-11 42.0 0.1 8.8e-11 42.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF4536 PF15055.6 OAG11143.1 - 0.067 13.4 3.7 0.12 12.7 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) Ral PF11058.8 OAG11143.1 - 0.5 10.0 0.1 0.5 10.0 0.1 2.3 4 0 0 4 4 4 0 Antirestriction protein Ral Rpr2 PF04032.16 OAG11143.1 - 0.88 9.9 3.1 1.3 9.4 0.1 2.2 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain 2OG-FeII_Oxy_3 PF13640.6 OAG11144.1 - 1.2e-08 35.7 0.0 2.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UDPG_MGDP_dh_N PF03721.14 OAG11145.1 - 4.4e-53 179.6 0.0 9e-53 178.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OAG11145.1 - 7e-33 113.2 0.8 4.2e-27 94.6 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OAG11145.1 - 9.9e-29 99.4 0.0 1.8e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Pox_A28 PF04584.14 OAG11145.1 - 0.01 16.1 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A28 family Sacchrp_dh_NADP PF03435.18 OAG11145.1 - 0.011 15.9 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 OAG11145.1 - 0.095 12.8 0.1 3.4 7.8 0.0 3.1 3 1 0 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain TPT PF03151.16 OAG11146.1 - 2.1e-34 119.2 14.5 2.4e-34 119.0 14.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OAG11146.1 - 3.4e-06 26.5 17.7 4.6e-06 26.0 17.7 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAG11146.1 - 0.00041 20.5 27.7 0.037 14.2 7.4 2.6 1 1 2 3 3 3 2 EamA-like transporter family DPM3 PF08285.11 OAG11146.1 - 8.3 6.7 8.3 1.7 8.9 1.0 2.8 1 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF726 PF05277.12 OAG11149.1 - 2.6e-117 391.6 0.1 3.8e-117 391.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 OAG11149.1 - 0.022 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Cutinase ORMDL PF04061.14 OAG11149.1 - 0.22 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 ORMDL family adh_short_C2 PF13561.6 OAG11151.1 - 6e-57 192.9 0.1 7.3e-57 192.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG11151.1 - 2.8e-45 154.2 0.0 3.5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG11151.1 - 5.9e-13 49.1 0.2 1.1e-12 48.2 0.2 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG11151.1 - 0.0042 16.1 0.1 0.007 15.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG11151.1 - 0.0051 16.3 0.1 0.01 15.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 OAG11151.1 - 0.069 12.5 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rep_1B PF17873.1 OAG11151.1 - 0.41 10.6 2.0 2.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Replicase polyprotein 1ab FMO-like PF00743.19 OAG11152.1 - 1e-14 53.9 0.9 5.3e-13 48.2 0.9 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG11152.1 - 5.8e-13 48.8 0.0 2.8e-11 43.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG11152.1 - 3.2e-10 40.1 0.0 1.2e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG11152.1 - 7.8e-08 31.9 0.0 1.2e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG11152.1 - 2.6e-06 26.8 0.0 0.0052 16.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG11152.1 - 0.00026 20.7 0.1 0.0077 15.8 0.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG11152.1 - 0.0019 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 OAG11152.1 - 0.0071 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG11152.1 - 0.0075 16.3 0.0 1.2 9.1 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 OAG11152.1 - 0.01 14.9 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG11152.1 - 0.032 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAG11152.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Lipase_GDSL_2 PF13472.6 OAG11153.1 - 1e-12 48.8 2.5 1.3e-12 48.5 2.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG11153.1 - 6.5e-05 23.0 0.6 9.3e-05 22.5 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RE_AccI PF09545.10 OAG11153.1 - 0.088 11.8 0.5 0.22 10.5 0.1 1.6 1 1 1 2 2 2 0 AccI restriction endonuclease Abhydrolase_1 PF00561.20 OAG11154.1 - 3.8e-20 72.6 0.0 1e-15 58.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAG11154.1 - 2.9e-18 65.9 0.0 5.7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein ESSS PF10183.9 OAG11154.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Acetyltransf_1 PF00583.25 OAG11156.1 - 1.2e-10 41.6 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG11156.1 - 6.3e-08 32.6 0.0 8.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG11156.1 - 1.7e-07 31.6 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG11156.1 - 0.0031 17.4 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAG11156.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 OAG11157.1 - 5.7e-28 97.9 32.7 5.7e-28 97.9 32.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily EthD PF07110.11 OAG11158.1 - 5.2e-09 37.1 0.1 8e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG11158.1 - 1.1e-05 25.8 0.0 1.7e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase FAD_binding_4 PF01565.23 OAG11159.1 - 5.6e-22 78.0 5.1 1.3e-21 76.7 5.1 1.7 1 0 0 1 1 1 1 FAD binding domain Chitin_bind_1 PF00187.19 OAG11159.1 - 2.3e-11 43.9 57.5 2.1e-05 24.9 23.9 3.1 2 2 1 3 3 3 2 Chitin recognition protein BBE PF08031.12 OAG11159.1 - 3e-11 43.2 0.1 5.6e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Astacin PF01400.24 OAG11161.1 - 3.9e-13 49.5 0.0 7.4e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 OAG11161.1 - 3.4e-05 24.1 0.0 5.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OAG11161.1 - 0.0004 20.9 0.0 0.00084 19.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAG11161.1 - 0.00048 19.8 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 OAG11161.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF4953 PF16313.5 OAG11161.1 - 0.017 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 OAG11161.1 - 0.041 13.5 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 OAG11161.1 - 0.045 13.6 2.4 0.11 12.4 2.3 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 OAG11161.1 - 0.05 12.6 0.1 0.096 11.6 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 OAG11161.1 - 0.08 11.5 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.6 OAG11161.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MotY_N PF18393.1 OAG11161.1 - 0.19 11.8 0.0 20 5.3 0.0 2.2 2 0 0 2 2 2 0 MotY N-terminal domain DnaJ PF00226.31 OAG11162.1 - 9.8e-15 54.4 0.9 1.6e-14 53.8 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain HeLo PF14479.6 OAG11163.1 - 5e-20 72.2 0.0 9.4e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.7 OAG11164.1 - 1.9e-20 73.3 0.1 3.4e-05 24.4 0.0 6.2 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 OAG11164.1 - 1.6e-17 63.7 0.0 9.1e-17 61.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG11164.1 - 1.6e-17 63.8 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 OAG11164.1 - 4.2e-14 51.3 15.7 0.084 13.5 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 OAG11164.1 - 1.2e-12 48.1 6.3 0.021 15.4 0.0 6.7 9 0 0 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG11164.1 - 3.5e-11 43.1 7.7 0.71 10.3 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG11164.1 - 3.4e-05 24.1 20.8 0.48 11.0 0.1 7.7 8 0 0 8 8 8 3 Ankyrin repeat Kdo PF06293.14 OAG11164.1 - 0.024 14.0 0.0 0.062 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3886 PF13025.6 OAG11164.1 - 0.036 14.2 2.0 0.1 12.8 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF4190 PF13828.6 OAG11165.1 - 0.033 13.9 3.0 2.4 8.0 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) adh_short PF00106.25 OAG11166.1 - 1.5e-26 93.1 0.0 4e-26 91.7 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG11166.1 - 9.6e-17 61.3 0.0 1.1e-15 57.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG11166.1 - 7.4e-09 35.8 0.3 2.2e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 OAG11166.1 - 0.0034 16.8 0.2 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG11166.1 - 0.009 15.5 0.2 0.044 13.2 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OAG11166.1 - 0.017 14.8 0.1 0.04 13.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 OAG11166.1 - 0.023 15.1 0.1 0.048 14.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 OAG11166.1 - 0.031 13.4 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 OAG11166.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Helicase_RecD PF05127.14 OAG11166.1 - 0.034 14.0 0.4 0.08 12.8 0.1 1.7 2 0 0 2 2 2 0 Helicase FAD_binding_3 PF01494.19 OAG11166.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thiolase_N PF00108.23 OAG11166.1 - 0.11 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain THF_DHG_CYH_C PF02882.19 OAG11166.1 - 0.12 11.7 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2_5_RNA_ligase2 PF13563.6 OAG11167.1 - 2.2e-25 89.3 0.0 4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 OAG11167.1 - 3.9e-20 71.9 0.0 6.8e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 OAG11167.1 - 4.4e-19 69.0 0.1 1.1e-18 67.8 0.1 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 OAG11167.1 - 3.4e-06 26.7 0.0 1.5e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 OAG11167.1 - 7.5e-06 26.2 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OAG11167.1 - 0.01 16.0 0.1 0.028 14.6 0.1 1.7 1 0 0 1 1 1 0 Cid1 family poly A polymerase WD40 PF00400.32 OAG11168.1 - 8.2e-111 358.8 73.6 4.1e-10 40.1 0.6 12.8 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG11168.1 - 9.4e-33 112.4 24.0 0.017 15.4 0.4 12.0 2 1 9 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 OAG11168.1 - 2.4e-25 89.4 1.1 5.6e-25 88.2 0.9 1.8 2 0 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 OAG11168.1 - 9.9e-20 70.7 28.7 0.0032 16.5 2.1 11.1 1 1 6 8 8 8 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG11168.1 - 8.9e-18 64.2 42.6 0.0072 15.0 0.0 11.9 2 1 8 11 11 11 9 Nucleoporin Nup120/160 HET PF06985.11 OAG11168.1 - 2.1e-15 57.4 4.9 4.8e-13 49.7 0.3 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40_like PF17005.5 OAG11168.1 - 0.00061 19.2 2.0 0.35 10.1 0.2 4.4 4 2 2 7 7 7 1 WD40-like domain DUF5114 PF17141.4 OAG11168.1 - 0.00099 19.6 0.0 51 4.5 0.0 6.7 5 2 5 10 10 10 0 Domain of unknown function (DUF5114) CDtoxinA PF03498.14 OAG11168.1 - 0.003 17.1 0.3 1 8.9 0.1 4.3 3 2 2 5 5 5 1 Cytolethal distending toxin A/C domain AAA_19 PF13245.6 OAG11168.1 - 0.023 15.0 1.1 0.93 9.8 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG11168.1 - 0.027 14.9 0.0 0.07 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OAG11168.1 - 0.047 14.1 0.1 0.4 11.1 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HARP PF07443.13 OAG11168.1 - 0.14 11.8 1.8 42 3.9 0.0 4.9 4 0 0 4 4 4 0 HepA-related protein (HARP) DUF1652 PF07865.11 OAG11168.1 - 0.15 11.9 0.0 81 3.2 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) Dabb PF07876.12 OAG11169.1 - 8.3e-22 77.6 0.0 9.3e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain GFA PF04828.14 OAG11170.1 - 5.1e-19 68.4 0.6 5.1e-19 68.4 0.6 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme MANEC PF07502.14 OAG11171.1 - 0.003 17.8 2.2 0.15 12.3 0.1 2.6 2 0 0 2 2 2 2 MANEC domain PAN_4 PF14295.6 OAG11171.1 - 0.026 14.4 1.3 0.026 14.4 1.3 3.3 3 1 0 3 3 3 0 PAN domain Glyco_hydro_61 PF03443.14 OAG11172.1 - 1.2e-55 188.7 0.2 1.4e-55 188.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4249 PF14054.6 OAG11172.1 - 0.0086 15.7 0.8 0.016 14.8 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4249) Sec34 PF04136.15 OAG11173.1 - 9.1e-50 168.4 0.5 1.6e-49 167.6 0.5 1.4 1 0 0 1 1 1 1 Sec34-like family RCC1 PF00415.18 OAG11174.1 - 2.4e-30 104.9 2.0 0.00018 22.1 0.0 7.5 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG11174.1 - 2.7e-11 43.0 23.3 4e-06 26.5 0.7 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Goodbye PF17109.5 OAG11175.1 - 3.4e-15 56.5 0.1 1.9e-14 54.2 0.0 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 OAG11175.1 - 1.5e-05 25.0 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG11175.1 - 4e-05 23.9 0.1 0.00027 21.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG11175.1 - 0.0032 17.9 0.0 0.016 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain ANAPC3 PF12895.7 OAG11175.1 - 0.0041 17.3 0.4 0.018 15.3 0.4 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 OAG11175.1 - 0.0063 16.5 0.1 0.36 10.9 0.1 2.9 2 0 0 2 2 2 1 Putative TPR-like repeat NB-ARC PF00931.22 OAG11175.1 - 0.011 15.0 0.0 0.079 12.1 0.0 2.4 1 1 0 1 1 1 0 NB-ARC domain TPR_2 PF07719.17 OAG11175.1 - 0.011 15.8 3.2 2.2 8.6 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG11175.1 - 0.02 15.4 2.8 4.3 7.9 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG11175.1 - 0.024 15.5 4.9 42 5.3 0.2 5.1 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_19 PF13245.6 OAG11175.1 - 0.091 13.1 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAG11175.1 - 0.11 11.9 0.5 7.1 6.0 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein TPR_12 PF13424.6 OAG11175.1 - 0.13 12.6 3.1 2.3 8.6 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat FliS PF02561.14 OAG11175.1 - 0.13 12.6 1.0 2.7 8.3 0.2 3.4 4 0 0 4 4 2 0 Flagellar protein FliS TPR_16 PF13432.6 OAG11175.1 - 0.17 12.6 8.6 0.62 10.8 1.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat GASA PF02704.14 OAG11175.1 - 0.76 10.0 10.2 1.6 8.9 10.2 1.5 1 0 0 1 1 1 0 Gibberellin regulated protein Cauli_AT PF03233.13 OAG11175.1 - 0.78 9.6 3.0 2.1 8.3 3.0 1.7 1 0 0 1 1 1 0 Aphid transmission protein DUF3135 PF11333.8 OAG11175.1 - 1.1 9.5 4.5 2.6 8.4 0.3 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF3135) FAM184 PF15665.5 OAG11175.1 - 5.7 6.7 12.0 0.51 10.1 6.4 2.0 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF3915 PF13054.6 OAG11176.1 - 0.024 14.6 2.9 0.046 13.7 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Auts2 PF15336.6 OAG11176.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein FAM27 PF15832.5 OAG11176.1 - 7.7 7.1 13.2 0.43 11.2 3.6 2.3 2 0 0 2 2 2 0 FAM27 D and E protein family HSP9_HSP12 PF04119.12 OAG11177.1 - 3.3e-28 97.8 4.5 4.9e-28 97.3 4.5 1.3 1 0 0 1 1 1 1 Heat shock protein 9/12 Fig1 PF12351.8 OAG11178.1 - 5e-59 199.4 4.8 5e-59 199.4 4.8 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 OAG11178.1 - 2.3e-09 37.2 8.3 3.8e-09 36.5 8.3 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 OAG11178.1 - 0.048 12.7 12.1 0.13 11.3 12.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF202 PF02656.15 OAG11178.1 - 5.1 7.6 14.0 1.1 9.7 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) SHMT PF00464.19 OAG11179.1 - 2.4e-203 675.1 0.0 2.8e-203 674.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 OAG11179.1 - 1e-05 24.9 0.0 2.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAG11179.1 - 0.002 17.5 0.0 0.0052 16.1 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAG11179.1 - 0.0021 17.1 0.1 0.0031 16.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG11179.1 - 0.056 12.7 0.1 0.16 11.2 0.1 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family BLACT_WH PF17778.1 OAG11180.1 - 3.5e-19 68.5 0.1 6.4e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 OAG11180.1 - 8.8e-13 48.7 4.1 8.8e-11 42.2 4.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG11180.1 - 4.5e-05 23.0 1.3 9.7e-05 22.0 1.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG11180.1 - 0.041 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain N6-adenineMlase PF10237.9 OAG11181.1 - 1.6e-53 180.8 0.0 1.9e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 OAG11181.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SGT1 PF07093.11 OAG11183.1 - 1.1e-76 258.6 0.2 1.1e-76 258.6 0.2 2.3 1 1 1 2 2 2 2 SGT1 protein COesterase PF00135.28 OAG11184.1 - 1.8e-60 205.3 0.0 2.9e-59 201.3 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG11184.1 - 5.6e-08 32.9 0.5 4.2e-07 30.0 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG11184.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family HTH_AsnC-type PF13404.6 OAG11184.1 - 0.035 13.9 0.1 0.084 12.7 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Say1_Mug180 PF10340.9 OAG11184.1 - 0.066 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase UIM PF02809.20 OAG11184.1 - 0.13 12.3 0.4 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif adh_short PF00106.25 OAG11185.1 - 9e-35 119.9 0.0 1.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG11185.1 - 9e-27 94.1 0.1 1.6e-26 93.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG11185.1 - 2.4e-05 24.4 0.3 0.0061 16.5 0.0 2.2 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 OAG11185.1 - 0.0085 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG11185.1 - 0.032 14.5 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 OAG11185.1 - 0.094 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain YjeF_N PF03853.15 OAG11185.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Shikimate_DH PF01488.20 OAG11185.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CMD PF02627.20 OAG11186.1 - 1.5e-19 69.8 0.0 2.1e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family p450 PF00067.22 OAG11187.1 - 6.7e-70 236.1 0.0 8.2e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 OAG11188.1 - 1.3e-24 87.3 0.0 5.6e-19 68.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG11188.1 - 6.8e-15 55.0 0.0 1.2e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG11188.1 - 2e-14 54.7 1.0 2.8e-14 54.2 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG11188.1 - 0.008 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Bestrophin PF01062.21 OAG11190.1 - 3.5e-36 125.1 0.1 5.1e-36 124.6 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 OAG11190.1 - 0.0038 16.0 0.2 0.0054 15.5 0.2 1.1 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DUF805 PF05656.14 OAG11190.1 - 0.33 11.4 1.3 2 8.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Macoilin PF09726.9 OAG11191.1 - 5.1 5.5 10.9 6.7 5.1 10.9 1.1 1 0 0 1 1 1 0 Macoilin family Trypan_PARP PF05887.11 OAG11191.1 - 7.9 6.5 13.2 0.45 10.5 7.7 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) BLOC1_2 PF10046.9 OAG11193.1 - 0.024 14.9 0.3 0.032 14.5 0.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 peroxidase PF00141.23 OAG11194.1 - 1.9e-27 96.5 0.0 2.6e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase HA PF03457.14 OAG11194.1 - 0.12 12.7 0.1 4.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Helicase associated domain WLM PF08325.10 OAG11195.1 - 3.8e-26 92.3 0.0 9.2e-26 91.1 0.0 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 OAG11195.1 - 1.7e-10 41.3 0.1 3.7e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Siva PF05458.12 OAG11195.1 - 0.2 11.3 5.7 0.36 10.5 5.7 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Zn_ribbon_17 PF17120.5 OAG11195.1 - 2.6 7.7 9.4 5.9 6.6 9.4 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type adh_short_C2 PF13561.6 OAG11196.1 - 1.2e-30 106.8 2.9 5.3e-30 104.7 2.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG11196.1 - 2.5e-27 95.6 4.9 1.5e-24 86.6 0.2 2.8 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.10 OAG11196.1 - 0.00014 21.9 6.8 0.019 14.9 0.2 3.2 2 1 1 3 3 3 2 KR domain Astacin PF01400.24 OAG11197.1 - 4.5e-13 49.2 1.1 2e-09 37.4 0.6 2.4 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 OAG11197.1 - 0.053 13.7 0.6 0.093 12.9 0.6 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAG11197.1 - 0.12 12.0 0.4 0.24 11.0 0.4 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Adenylsucc_synt PF00709.21 OAG11198.1 - 8.1e-175 581.7 0.1 9.1e-175 581.6 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Peptidase_M43 PF05572.13 OAG11199.1 - 1.9e-14 53.9 0.0 3.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OAG11199.1 - 0.0022 18.2 0.1 0.0031 17.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OAG11199.1 - 0.017 15.0 1.1 0.021 14.7 1.1 1.4 1 1 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 OAG11199.1 - 0.018 15.6 0.2 0.034 14.7 0.1 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OAG11199.1 - 0.062 12.2 0.2 0.087 11.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 OAG11199.1 - 0.073 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 OAG11199.1 - 0.22 10.1 2.2 0.33 9.5 2.2 1.2 1 0 0 1 1 1 0 Putative peptidase family Lipase_GDSL_2 PF13472.6 OAG11200.1 - 2.1e-13 51.0 0.9 2.6e-13 50.8 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ALGX PF16822.5 OAG11200.1 - 0.00032 20.5 0.3 0.0088 15.7 0.1 2.1 2 0 0 2 2 2 1 SGNH hydrolase-like domain, acetyltransferase AlgX Lipase_GDSL PF00657.22 OAG11200.1 - 0.0061 16.6 0.3 0.015 15.3 0.3 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peptidase_S28 PF05577.12 OAG11201.1 - 3.5e-48 164.5 1.5 7.2e-48 163.4 1.5 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 OAG11201.1 - 1.2e-06 27.4 0.3 0.0068 15.1 0.1 2.3 2 0 0 2 2 2 2 PS-10 peptidase S37 DUF2920 PF11144.8 OAG11201.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Amidase PF01425.21 OAG11202.1 - 2.3e-93 313.6 0.0 1.7e-92 310.7 0.0 1.9 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 OAG11203.1 - 3.9e-25 88.5 26.5 3.9e-25 88.5 26.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 OAG11204.1 - 8.2e-09 35.5 8.9 1.8e-08 34.3 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAG11205.1 - 1.9e-47 162.1 0.0 2.6e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1890 PF09001.11 OAG11205.1 - 0.12 12.7 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) Methyltransf_2 PF00891.18 OAG11206.1 - 6e-23 81.2 0.0 1e-22 80.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 OAG11206.1 - 0.0088 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 OAG11206.1 - 0.063 13.3 0.1 0.63 10.1 0.0 2.2 1 1 1 2 2 2 0 Dimerisation domain adh_short PF00106.25 OAG11207.1 - 1.9e-41 141.7 0.0 3.4e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG11207.1 - 3.6e-32 111.8 0.0 4.9e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG11207.1 - 1e-11 45.1 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG11207.1 - 4.6e-06 26.2 0.0 5.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 OAG11207.1 - 0.022 14.5 0.5 0.067 13.0 0.5 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 OAG11207.1 - 0.079 12.8 0.1 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding ketoacyl-synt PF00109.26 OAG11208.1 - 2.8e-72 243.3 0.1 7.5e-72 241.9 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAG11208.1 - 2.6e-36 124.2 0.2 8.8e-36 122.5 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 OAG11208.1 - 3.3e-22 78.2 0.0 2.3e-21 75.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 OAG11208.1 - 1.5e-19 70.7 0.2 7.3e-18 65.1 0.1 2.6 3 0 0 3 3 3 1 Acyl transferase domain PS-DH PF14765.6 OAG11208.1 - 1.6e-18 67.0 0.0 2.8e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 OAG11208.1 - 6.1e-17 62.2 0.0 1.5e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 OAG11208.1 - 1.7e-14 54.2 0.0 4.7e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold PP-binding PF00550.25 OAG11208.1 - 2.4e-13 50.2 2.1 5.4e-13 49.1 1.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 OAG11208.1 - 2.6e-12 46.9 0.0 2.7e-11 43.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG11208.1 - 6e-12 46.1 0.0 1.9e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG11208.1 - 2.3e-10 41.0 0.0 6e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 OAG11208.1 - 1.1e-08 35.1 4.2 2.4e-06 27.5 0.8 3.5 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_31 PF13847.6 OAG11208.1 - 5.8e-08 32.7 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.21 OAG11208.1 - 9.9e-08 31.7 0.1 5.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family KAsynt_C_assoc PF16197.5 OAG11208.1 - 6.1e-05 23.4 0.0 0.00022 21.6 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ubie_methyltran PF01209.18 OAG11208.1 - 8.3e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OAG11208.1 - 0.0016 18.1 0.0 0.028 14.0 0.0 2.7 3 0 0 3 3 3 1 Nodulation protein S (NodS) DLH PF01738.18 OAG11208.1 - 0.004 16.7 0.0 0.084 12.4 0.0 2.7 3 0 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OAG11208.1 - 0.0073 16.9 4.3 0.0073 16.9 4.3 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family COesterase PF00135.28 OAG11208.1 - 0.015 14.2 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Carboxylesterase family Methyltransf_28 PF02636.17 OAG11208.1 - 0.023 14.3 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AXE1 PF05448.12 OAG11208.1 - 0.22 10.2 0.0 5.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lactamase_B PF00753.27 OAG11209.1 - 7.4e-13 48.9 1.3 1.5e-12 47.9 1.3 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG11209.1 - 6.1e-06 25.9 0.1 1.1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Trp_DMAT PF11991.8 OAG11210.1 - 1.1e-87 294.9 0.0 1.5e-87 294.4 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 OAG11211.1 - 1e-49 169.6 0.0 1.3e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 OAG11212.1 - 1.5e-53 182.1 0.0 1.9e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG11212.1 - 3.7e-35 121.5 0.0 6.5e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 OAG11212.1 - 2.1e-06 27.2 0.4 0.00039 19.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG11212.1 - 0.00012 21.3 0.2 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG11212.1 - 0.00097 18.4 0.0 0.0091 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG11212.1 - 0.0038 17.4 0.1 0.0099 16.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG11212.1 - 0.011 14.9 0.6 0.075 12.3 0.1 2.4 3 0 0 3 3 3 0 Thi4 family DAO PF01266.24 OAG11212.1 - 0.011 15.3 1.4 0.069 12.7 0.4 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG11212.1 - 0.026 13.8 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAG11212.1 - 0.042 12.9 0.2 0.083 11.9 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Myb_DNA-binding PF00249.31 OAG11214.1 - 4e-32 110.1 9.4 7.4e-17 61.3 0.4 3.0 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG11214.1 - 7.1e-24 83.8 4.7 2.1e-14 53.5 0.4 3.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OAG11214.1 - 3.2e-06 27.1 0.1 0.0021 18.1 0.0 2.1 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OAG11214.1 - 4e-05 23.4 0.0 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OAG11214.1 - 0.014 15.6 2.3 1.6 8.9 0.1 3.3 2 2 1 3 3 3 0 Rap1 Myb domain Rap1_C PF11626.8 OAG11214.1 - 0.021 14.9 0.8 0.041 14.0 0.3 1.8 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OAG11214.1 - 0.026 14.7 1.2 0.28 11.4 0.2 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF3606 PF12244.8 OAG11214.1 - 0.037 13.9 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DUF2508 PF10704.9 OAG11214.1 - 0.17 12.1 0.0 0.58 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Beta_helix PF13229.6 OAG11217.1 - 3.9e-11 43.0 16.2 9e-08 32.1 4.2 2.6 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 OAG11217.1 - 2.3e-07 30.3 9.1 0.00032 20.0 0.7 2.9 2 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) MinC_C PF03775.16 OAG11217.1 - 0.3 11.1 3.0 2.1 8.4 0.6 2.5 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain Otopetrin PF03189.13 OAG11218.1 - 0.014 14.2 0.2 0.017 14.0 0.2 1.0 1 0 0 1 1 1 0 Otopetrin DUF4328 PF14219.6 OAG11219.1 - 0.1 12.1 4.1 0.51 9.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) DUF2663 PF10864.8 OAG11219.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) Cytochrom_B_C PF00032.17 OAG11219.1 - 0.38 11.1 7.0 6.6 7.1 0.2 3.0 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DPM3 PF08285.11 OAG11219.1 - 1.4 9.2 9.5 1.1 9.5 0.1 2.9 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3043 PF11241.8 OAG11219.1 - 1.5 8.8 5.0 1.2 9.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3043) Ras PF00071.22 OAG11220.1 - 6.6e-52 175.4 0.2 3.9e-51 172.9 0.2 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG11220.1 - 8.5e-19 67.9 0.0 6.2e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG11220.1 - 0.00022 20.7 0.0 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG11220.1 - 0.022 14.3 0.1 4.7 6.7 0.0 2.9 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OAG11220.1 - 0.023 14.3 0.1 0.34 10.4 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG11220.1 - 0.025 14.5 0.0 9 6.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 OAG11220.1 - 0.047 13.0 0.0 0.093 12.0 0.0 1.5 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.23 OAG11220.1 - 0.053 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG11220.1 - 0.067 13.6 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OAG11220.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 OAG11221.1 - 4.1e-78 262.9 0.0 5e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG11221.1 - 4.3e-17 62.8 0.0 9.2e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAG11221.1 - 1.2e-14 54.0 2.3 1.4e-14 53.8 0.6 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus HAD_2 PF13419.6 OAG11222.1 - 6.8e-07 29.5 0.0 1.8e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG11222.1 - 9.5e-07 29.3 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG11222.1 - 1.2e-06 28.4 0.0 2.7e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Alpha_L_fucos PF01120.17 OAG11222.1 - 0.015 14.8 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase CENP-T_C PF15511.6 OAG11223.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAG11223.1 - 1.3e-05 25.6 0.2 1.5e-05 25.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 OAG11223.1 - 4.2e-05 23.6 0.2 6e-05 23.1 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OAG11223.1 - 6.3e-05 23.2 0.1 0.00011 22.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAG11223.1 - 0.00016 21.9 0.1 0.00022 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OAG11223.1 - 0.0037 17.3 0.0 0.0044 17.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG11223.1 - 0.0063 16.5 0.0 0.0075 16.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 OAG11223.1 - 0.028 14.2 0.2 0.034 14.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 OAG11223.1 - 0.066 13.7 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 OAG11223.1 - 0.075 13.0 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 OAG11224.1 - 5.9e-50 169.0 0.4 6.9e-50 168.8 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAG11224.1 - 9e-06 26.0 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAG11224.1 - 7.3e-05 22.9 0.4 0.00012 22.1 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAG11224.1 - 0.0049 17.1 0.0 0.0096 16.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 OAG11224.1 - 0.014 15.9 0.7 0.019 15.5 0.7 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 OAG11224.1 - 0.041 14.0 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Redoxin PF08534.10 OAG11225.1 - 4.3e-06 26.5 0.0 0.00027 20.7 0.0 2.0 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 OAG11225.1 - 2e-05 24.5 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 OAG11225.1 - 4.1e-05 23.7 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Exo5 PF09810.9 OAG11226.1 - 5.2e-123 411.2 0.0 7.3e-123 410.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 OAG11226.1 - 0.0014 18.6 0.0 0.19 11.6 0.0 2.7 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Glyco_hydro_43 PF04616.14 OAG11227.1 - 1.8e-34 119.4 8.5 2.5e-34 118.9 8.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RED_N PF07808.13 OAG11228.1 - 4e-07 29.9 1.7 4.9e-06 26.3 0.3 2.7 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF3741 PF12552.8 OAG11228.1 - 0.081 12.9 1.7 0.3 11.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) Plectin PF00681.20 OAG11228.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat Proteasome PF00227.26 OAG11229.1 - 7.6e-48 162.5 0.2 9.1e-48 162.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit JmjC PF02373.22 OAG11230.1 - 5.2e-09 36.5 0.0 1e-07 32.4 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OAG11230.1 - 7.4e-08 32.4 0.0 3.2e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.29 OAG11230.1 - 6e-07 29.3 7.2 6e-07 29.3 7.2 2.4 2 0 0 2 2 2 1 PHD-finger JHD PF17811.1 OAG11230.1 - 2.7e-05 24.6 0.3 5.6e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 Jumonji helical domain Dickkopf_N PF04706.12 OAG11230.1 - 0.14 12.6 6.8 2.4 8.7 0.5 2.8 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region PHD_2 PF13831.6 OAG11230.1 - 3 7.5 10.3 1 9.0 6.5 2.3 2 0 0 2 2 2 0 PHD-finger RRM_1 PF00076.22 OAG11231.1 - 3e-19 68.6 1.1 1.2e-18 66.7 0.3 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG11231.1 - 3.7e-05 23.3 0.0 4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG11231.1 - 0.053 13.4 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif XFP_N PF09364.10 OAG11232.1 - 3.5e-171 569.0 0.0 5e-171 568.5 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 OAG11232.1 - 4.7e-82 274.3 0.0 7e-82 273.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 OAG11232.1 - 3.5e-81 271.1 0.0 6.1e-81 270.3 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DUF5352 PF17303.2 OAG11232.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5352) Hexokinase_2 PF03727.16 OAG11233.1 - 3.7e-81 272.1 0.0 4.9e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG11233.1 - 5.4e-69 232.1 0.0 8e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase AAA PF00004.29 OAG11234.1 - 7.7e-55 184.9 0.0 1.5e-39 135.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG11234.1 - 1.5e-10 40.7 0.0 4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG11234.1 - 3.2e-10 40.7 0.2 0.0012 19.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG11234.1 - 6.6e-10 39.4 0.1 0.00022 21.5 0.0 3.8 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 OAG11234.1 - 2.1e-08 33.7 0.0 0.0029 16.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 OAG11234.1 - 6.5e-08 32.3 0.2 4.3e-06 26.4 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_24 PF13479.6 OAG11234.1 - 1.8e-07 31.1 0.0 0.013 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OAG11234.1 - 1.8e-07 31.4 0.1 1.8e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG11234.1 - 1.9e-07 31.0 0.1 0.017 14.9 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAG11234.1 - 8e-07 29.1 0.0 0.0027 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAG11234.1 - 1.5e-06 28.8 0.0 0.02 15.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 OAG11234.1 - 3.2e-06 26.7 0.0 0.0084 15.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAG11234.1 - 3.6e-06 27.2 0.0 0.18 11.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 OAG11234.1 - 8.8e-06 25.8 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAG11234.1 - 1.3e-05 25.6 0.0 0.059 13.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OAG11234.1 - 4.3e-05 23.3 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 OAG11234.1 - 7.1e-05 22.8 0.2 0.089 12.7 0.0 3.1 3 0 0 3 3 2 1 NACHT domain CDC48_N PF02359.18 OAG11234.1 - 0.00014 22.0 0.0 0.00038 20.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_28 PF13521.6 OAG11234.1 - 0.00015 22.1 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 OAG11234.1 - 0.00015 21.0 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TsaE PF02367.17 OAG11234.1 - 0.00019 21.4 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OAG11234.1 - 0.00026 20.4 0.1 0.023 14.0 0.1 2.5 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 OAG11234.1 - 0.00028 20.5 0.1 0.074 12.6 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 OAG11234.1 - 0.00037 21.0 0.1 0.16 12.5 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 OAG11234.1 - 0.0012 18.7 0.0 0.91 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG11234.1 - 0.0014 19.1 0.1 0.9 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG11234.1 - 0.0017 18.0 2.1 2.1 7.9 0.2 3.4 3 1 1 4 4 3 2 AAA domain PhoH PF02562.16 OAG11234.1 - 0.0018 17.7 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activat PF00158.26 OAG11234.1 - 0.0021 17.8 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 OAG11234.1 - 0.0038 17.0 0.1 0.6 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OAG11234.1 - 0.0054 16.6 0.0 0.75 9.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAG11234.1 - 0.0058 17.0 0.2 1 9.7 0.0 3.2 4 0 0 4 4 2 1 AAA domain ATPase_2 PF01637.18 OAG11234.1 - 0.0075 16.2 0.8 25 4.7 0.0 3.9 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 OAG11234.1 - 0.013 14.8 0.1 1.7 7.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 OAG11234.1 - 0.033 13.6 0.1 6.1 6.2 0.0 3.5 3 1 0 3 3 3 0 Bacterial TniB protein Parvo_NS1 PF01057.17 OAG11234.1 - 0.033 13.3 0.0 0.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 OAG11234.1 - 0.06 13.1 0.0 7 6.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 OAG11234.1 - 0.064 12.5 0.1 3.4 6.9 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin NTPase_1 PF03266.15 OAG11234.1 - 0.079 12.9 0.3 19 5.1 0.0 2.9 3 0 0 3 3 3 0 NTPase Rad17 PF03215.15 OAG11234.1 - 0.08 12.9 0.1 6.5 6.6 0.0 3.2 4 0 0 4 4 3 0 Rad17 P-loop domain KTI12 PF08433.10 OAG11234.1 - 0.12 11.8 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KxDL PF10241.9 OAG11235.1 - 2.1e-30 104.8 0.1 2.7e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 OAG11235.1 - 0.074 12.4 0.6 0.086 12.2 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MPLKIP PF15502.6 OAG11237.1 - 6.3e-05 23.1 1.4 0.00012 22.2 0.0 2.3 2 1 1 3 3 3 1 M-phase-specific PLK1-interacting protein SNRNP27 PF08648.12 OAG11237.1 - 0.00026 21.0 0.1 0.00058 19.9 0.1 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF4953 PF16313.5 OAG11237.1 - 0.036 13.3 0.2 0.046 12.9 0.2 1.1 1 0 0 1 1 1 0 Met-zincin Ribosomal_L19e PF01280.20 OAG11238.1 - 2.1e-60 202.9 7.4 2.1e-60 202.9 7.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e FUSC_2 PF13515.6 OAG11238.1 - 3.5e-31 108.0 6.4 3.5e-31 108.0 6.4 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAG11238.1 - 0.00014 21.8 0.2 0.0019 18.1 0.1 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 TFIID-18kDa PF02269.16 OAG11239.1 - 5e-26 90.5 0.1 1.6e-25 88.9 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TP_methylase PF00590.20 OAG11240.1 - 4e-24 85.8 0.8 7.1e-24 84.9 0.8 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF3736 PF12540.8 OAG11241.1 - 0.69 10.0 4.9 1.8 8.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) SET PF00856.28 OAG11243.1 - 1.3e-05 25.7 0.0 0.001 19.5 0.0 2.9 1 1 0 1 1 1 1 SET domain adh_short_C2 PF13561.6 OAG11245.1 - 1.1e-38 133.1 0.9 1.5e-38 132.7 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG11245.1 - 1.1e-36 126.2 0.2 1.4e-36 125.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG11245.1 - 1.1e-07 31.9 0.3 1.8e-07 31.3 0.3 1.2 1 0 0 1 1 1 1 KR domain 53-BP1_Tudor PF09038.10 OAG11245.1 - 0.032 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor HEM4 PF02602.15 OAG11246.1 - 4.9e-37 127.5 0.0 2.9e-36 125.0 0.0 2.1 2 1 0 2 2 2 1 Uroporphyrinogen-III synthase HemD DUF3644 PF12358.8 OAG11247.1 - 0.029 14.8 2.5 0.13 12.7 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) Osmo_CC PF08946.10 OAG11247.1 - 9.1 6.6 11.6 0.24 11.6 0.9 3.6 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Pyrid_ox_like PF16242.5 OAG11248.1 - 1.4e-22 79.9 0.0 2.1e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAG11248.1 - 4.3e-05 23.6 0.0 7.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DASH_Spc34 PF08657.10 OAG11249.1 - 2.3e-48 165.2 0.0 2.1e-23 83.4 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF724 PF05266.14 OAG11249.1 - 0.0057 16.5 0.6 0.0083 16.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DASH_Spc19 PF08287.11 OAG11249.1 - 0.011 15.7 3.6 0.016 15.1 3.6 1.3 1 0 0 1 1 1 0 Spc19 Spectrin PF00435.21 OAG11249.1 - 0.027 15.0 1.4 1.6 9.3 0.0 2.3 1 1 1 2 2 2 0 Spectrin repeat Tropomyosin_1 PF12718.7 OAG11249.1 - 0.03 14.5 4.6 2.4 8.3 0.2 2.2 1 1 1 2 2 2 0 Tropomyosin like DivIC PF04977.15 OAG11249.1 - 0.05 13.4 0.7 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator UCR_Fe-S_N PF10399.9 OAG11249.1 - 0.087 12.2 0.6 0.087 12.2 0.6 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TMF_DNA_bd PF12329.8 OAG11249.1 - 0.8 9.7 4.8 1.3 9.1 0.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Rpn3_C PF08375.11 OAG11250.1 - 5.1e-28 97.3 2.4 3.2e-27 94.7 1.1 2.6 2 1 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OAG11250.1 - 1.6e-21 76.8 0.2 5e-20 72.0 0.0 2.8 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 OAG11250.1 - 0.044 13.8 0.5 0.96 9.4 0.5 2.6 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family Sigma70_r1_2 PF00140.20 OAG11250.1 - 0.93 9.6 5.4 0.89 9.6 2.6 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Ank_2 PF12796.7 OAG11251.1 - 2.2e-20 73.0 8.3 9.1e-09 35.8 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG11251.1 - 7.2e-19 67.9 1.5 1.4e-08 35.1 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG11251.1 - 3.2e-14 51.6 5.6 0.00074 19.8 0.1 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OAG11251.1 - 6e-14 51.9 2.8 4.4e-05 23.7 0.2 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG11251.1 - 1.4e-08 34.8 9.8 0.0042 17.5 0.6 4.7 5 0 0 5 5 5 3 Ankyrin repeat NIF PF03031.18 OAG11252.1 - 3.1e-25 88.8 0.0 5.2e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OAG11252.1 - 2.3e-06 27.9 0.5 0.00041 20.7 0.1 2.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG11252.1 - 1.4e-05 24.9 0.4 0.00062 19.7 0.0 2.6 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 OAG11252.1 - 0.0012 19.3 0.1 0.0036 17.7 0.1 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF816 PF05674.12 OAG11252.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Biotin_lipoyl_2 PF13533.6 OAG11252.1 - 0.071 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like Dsh_C PF12316.8 OAG11252.1 - 8.4 6.7 10.7 20 5.5 10.7 1.6 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal GRAM PF02893.20 OAG11253.1 - 2.7e-30 104.6 4.7 7e-20 71.0 0.1 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 OAG11253.1 - 7.4e-30 103.8 0.0 1.6e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 OAG11253.1 - 2.6e-14 53.6 0.3 1.5e-13 51.1 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OAG11253.1 - 1.4e-07 31.8 0.6 5.7e-07 29.9 0.6 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 OAG11253.1 - 0.00012 22.1 0.2 0.00029 20.9 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 OAG11253.1 - 0.00064 20.0 0.2 0.0024 18.2 0.2 1.9 2 0 0 2 2 2 1 Plant pleckstrin homology-like region Glyco_tran_28_C PF04101.16 OAG11253.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 OAG11253.1 - 0.0084 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 OAG11253.1 - 0.02 15.1 0.3 0.049 13.9 0.3 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 OAG11253.1 - 0.074 12.9 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Asp PF00026.23 OAG11254.1 - 4.2e-110 368.1 0.0 4.9e-110 367.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG11254.1 - 1.4e-15 58.0 3.6 9.9e-14 52.0 2.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG11254.1 - 3.3e-06 27.7 0.1 0.03 15.0 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG11254.1 - 0.00067 20.2 0.0 0.64 10.6 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAG11254.1 - 0.00075 19.3 0.0 0.013 15.3 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal MIF4G PF02854.19 OAG11255.1 - 2e-23 83.2 0.6 5.6e-23 81.7 0.2 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 OAG11255.1 - 6.7e-20 71.2 0.0 1.7e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 MA3 domain SRP14 PF02290.15 OAG11256.1 - 2.6e-27 95.0 0.7 3e-27 94.8 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DOPA_dioxygen PF08883.11 OAG11257.1 - 2.5e-45 153.1 0.0 3.3e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family tRNA-synt_2 PF00152.20 OAG11258.1 - 3.2e-88 295.8 0.0 4.9e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG11258.1 - 6.2e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PHD PF00628.29 OAG11259.1 - 1.8e-12 47.0 21.3 6.8e-07 29.1 9.9 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 OAG11259.1 - 0.029 14.3 0.7 0.029 14.3 0.7 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 OAG11259.1 - 1.2 9.4 4.9 7 6.9 1.2 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAG11259.1 - 1.2 9.5 11.3 4.6 7.6 5.5 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_M24 PF00557.24 OAG11260.1 - 9.2e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 FIVAR PF07554.13 OAG11260.1 - 5 8.0 8.2 1.2 10.0 0.5 2.9 3 0 0 3 3 3 0 FIVAR domain Exo_endo_phos PF03372.23 OAG11261.1 - 3.8e-05 23.3 0.1 0.00019 21.0 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 OAG11262.1 - 9.8e-66 221.9 2.4 1.9e-64 217.7 0.7 2.9 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GPP34 PF05719.11 OAG11265.1 - 1.2e-67 227.9 0.2 1.6e-67 227.5 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.25 OAG11266.1 - 6.2e-11 42.5 0.1 9e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OAG11266.1 - 3.9e-09 36.6 0.1 1e-08 35.3 0.2 1.6 1 1 1 2 2 2 1 Acyl-carrier Ribosomal_L50 PF10501.9 OAG11266.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.6 1 1 0 1 1 1 0 Ribosomal subunit 39S Fer4 PF00037.27 OAG11267.1 - 2.3e-14 52.5 15.3 2.1e-08 33.7 3.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OAG11267.1 - 5.6e-13 49.3 9.8 8.4e-13 48.7 9.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAG11267.1 - 7.7e-11 42.8 7.9 2.5e-05 25.1 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OAG11267.1 - 1.1e-10 41.4 31.8 9.1e-07 28.9 12.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAG11267.1 - 5e-09 36.1 21.5 2.6e-06 27.4 12.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAG11267.1 - 6.1e-09 35.9 8.8 1e-08 35.2 8.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAG11267.1 - 2e-07 31.3 18.8 8.7e-05 22.9 10.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OAG11267.1 - 1e-06 28.6 16.9 0.0004 20.3 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 OAG11267.1 - 3.9e-06 26.6 12.1 0.0082 16.2 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OAG11267.1 - 7.7e-06 26.0 11.0 0.0003 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OAG11267.1 - 9.5e-05 22.9 11.4 0.005 17.4 12.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 OAG11267.1 - 0.011 16.7 15.7 0.018 15.9 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 OAG11267.1 - 0.024 14.8 5.0 1.1 9.6 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 OAG11267.1 - 0.025 15.1 15.0 0.75 10.4 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 OAG11267.1 - 0.1 12.8 9.2 1.5 9.0 1.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 OAG11267.1 - 0.11 12.7 5.7 0.47 10.6 0.5 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 OAG11267.1 - 0.64 10.9 11.6 1.8 9.4 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain SURF6 PF04935.12 OAG11268.1 - 1.8e-46 158.4 46.3 1.8e-46 158.4 46.3 4.1 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 OAG11268.1 - 9.6e-16 58.1 0.2 9.6e-16 58.1 0.2 8.8 7 2 0 7 7 7 2 60S ribosome biogenesis protein Rrp14 MIT PF04212.18 OAG11272.1 - 1.6e-14 53.7 0.8 4.3e-14 52.3 0.8 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PCI PF01399.27 OAG11273.1 - 7.9e-07 29.5 0.0 2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain Mad3_BUB1_I PF08311.12 OAG11274.1 - 1.3e-45 154.4 1.2 5e-45 152.5 1.1 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OAG11274.1 - 1.7e-14 53.8 0.0 8.2e-14 51.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.11 OAG11274.1 - 1.3e-08 34.9 0.0 1.1e-07 31.9 0.0 2.7 2 1 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 OAG11274.1 - 6.5e-08 32.2 0.0 1.7e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 OAG11274.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Kdo PF06293.14 OAG11274.1 - 0.02 14.3 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG11274.1 - 0.038 13.9 0.6 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG11274.1 - 0.093 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ADH_zinc_N PF00107.26 OAG11275.1 - 2.3e-25 89.1 0.0 4.8e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG11275.1 - 1.7e-18 66.5 1.8 3.1e-18 65.6 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG11275.1 - 9.7e-05 23.4 0.0 0.00019 22.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG11275.1 - 0.00067 19.0 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG11275.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAG11275.1 - 0.01 16.5 0.1 0.027 15.2 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAG11275.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 OAG11275.1 - 0.013 15.4 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N_2 PF16884.5 OAG11275.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase CFEM PF05730.11 OAG11276.1 - 8.4e-16 57.8 12.4 1.7e-15 56.8 12.4 1.5 1 0 0 1 1 1 1 CFEM domain BTP PF05232.12 OAG11276.1 - 0.079 13.0 0.3 0.079 13.0 0.3 3.4 5 0 0 5 5 5 0 Chlorhexidine efflux transporter p450 PF00067.22 OAG11277.1 - 2.7e-60 204.5 0.0 3.6e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Iso_dh PF00180.20 OAG11278.1 - 1.2e-89 300.8 0.0 1.5e-89 300.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4875 PF16175.5 OAG11278.1 - 0.019 15.1 0.1 0.06 13.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4875) PRK PF00485.18 OAG11279.1 - 0.00013 21.8 0.0 0.00053 19.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OAG11279.1 - 0.00041 20.5 0.0 0.00087 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAG11279.1 - 0.00045 19.5 0.4 0.00086 18.6 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 OAG11279.1 - 0.012 16.2 0.0 0.029 14.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OAG11279.1 - 0.023 14.6 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 NTPase SRP54 PF00448.22 OAG11279.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 OAG11279.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG11279.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 OAG11279.1 - 0.08 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 OAG11279.1 - 0.085 12.1 0.0 0.38 9.9 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain MeaB PF03308.16 OAG11279.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF463 PF04317.12 OAG11279.1 - 0.16 10.8 0.2 0.27 10.1 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 DUF3440 PF11922.8 OAG11279.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) MFS_1 PF07690.16 OAG11280.1 - 1.7e-30 106.1 28.7 1.7e-30 106.1 28.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2384 PF09722.10 OAG11280.1 - 0.17 11.9 0.1 0.52 10.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) Trp_oprn_chp PF09534.10 OAG11280.1 - 0.53 10.1 8.3 0.34 10.7 3.9 2.5 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM223 PF14640.6 OAG11280.1 - 1.9 8.6 6.2 9.6 6.3 0.3 3.2 3 0 0 3 3 3 0 Transmembrane protein 223 Fungal_trans PF04082.18 OAG11281.1 - 4.4e-25 88.2 2.0 7.7e-25 87.4 2.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DDHD PF02862.17 OAG11282.1 - 3.9e-61 207.1 5.3 7.9e-61 206.1 0.0 2.6 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.14 OAG11282.1 - 0.031 13.8 0.1 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) RNase_3_N PF18497.1 OAG11282.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain Hydrolase_4 PF12146.8 OAG11282.1 - 0.081 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WWE PF02825.20 OAG11282.1 - 0.097 13.3 0.0 0.36 11.5 0.0 1.9 1 0 0 1 1 1 0 WWE domain ApbA_C PF08546.11 OAG11284.1 - 3.3e-28 98.4 0.2 5.6e-28 97.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG11284.1 - 2.2e-20 72.8 0.0 3.5e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA zf-C2H2_2 PF12756.7 OAG11285.1 - 3.8e-24 84.9 6.4 1.9e-21 76.3 0.8 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAG11285.1 - 0.049 14.5 12.4 11 7.1 0.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2024 PF09630.10 OAG11285.1 - 0.052 13.4 4.3 0.88 9.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) TPR_18 PF13512.6 OAG11286.1 - 0.0092 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TrpP PF17099.5 OAG11286.1 - 0.19 11.5 0.3 0.26 11.0 0.3 1.1 1 0 0 1 1 1 0 Tryptophan transporter TrpP DSBA PF01323.20 OAG11287.1 - 5e-53 179.8 0.0 3.6e-29 101.9 0.0 3.0 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Phage_Capsid_P3 PF09018.11 OAG11289.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 P3 major capsid protein CYSTM PF12734.7 OAG11292.1 - 0.051 13.9 61.8 1.5e+03 -0.4 61.8 4.2 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance RRM_1 PF00076.22 OAG11293.1 - 9.1e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2950 PF11453.8 OAG11293.1 - 0.036 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) zf-CCCH_2 PF14608.6 OAG11295.1 - 5.3e-06 26.7 54.8 0.014 15.9 7.1 5.4 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 OAG11295.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.24 OAG11296.1 - 8e-25 88.0 0.0 2.4e-24 86.5 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG11296.1 - 3.7e-14 52.7 0.2 1.3e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG11296.1 - 2.1e-07 30.8 0.0 0.00015 21.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG11296.1 - 0.00045 19.5 0.0 0.00078 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 OAG11296.1 - 0.0011 17.8 0.0 0.0056 15.5 0.0 2.0 2 0 0 2 2 2 1 MCRA family Pyr_redox_2 PF07992.14 OAG11296.1 - 0.055 12.7 0.1 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CFEM PF05730.11 OAG11297.1 - 0.00046 20.2 2.5 0.0011 19.0 2.5 1.7 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 OAG11297.1 - 0.017 14.5 2.3 0.034 13.6 2.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DAP10 PF07213.11 OAG11297.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Zn_clus PF00172.18 OAG11299.1 - 1.4e-14 53.9 36.2 8.1e-08 32.3 12.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG11299.1 - 3.2e-05 23.1 0.1 5.9e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MOSC PF03473.17 OAG11300.1 - 5.2e-35 120.3 0.0 9.1e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG11300.1 - 2.1e-13 50.2 0.0 3.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Patatin PF01734.22 OAG11301.1 - 8.8e-15 55.4 0.0 2.6e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase AAA PF00004.29 OAG11303.1 - 5e-16 59.3 0.0 8.5e-08 32.7 0.0 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAG11303.1 - 1.3e-06 28.6 0.7 2.4e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA_5 PF07728.14 OAG11303.1 - 0.00012 22.1 0.0 0.00047 20.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAG11303.1 - 0.00052 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG11303.1 - 0.00059 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAG11303.1 - 0.00067 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAG11303.1 - 0.0027 18.0 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG11303.1 - 0.0038 17.1 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG11303.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG11303.1 - 0.0098 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 OAG11303.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 OAG11303.1 - 0.017 14.5 0.0 0.044 13.1 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 OAG11303.1 - 0.028 14.0 0.0 0.077 12.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAG11303.1 - 0.034 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 OAG11303.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 OAG11303.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 OAG11303.1 - 0.15 11.3 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 OAG11303.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 OAG11305.1 - 1.8e-27 96.1 0.0 4.3e-27 94.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ubiquitin PF00240.23 OAG11306.1 - 2.8e-25 87.9 0.0 3.1e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG11306.1 - 1.2e-15 57.0 0.1 1.4e-15 56.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG11306.1 - 0.00016 22.1 0.0 0.00048 20.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG11306.1 - 0.0055 16.6 0.0 0.0067 16.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAG11306.1 - 0.064 13.6 0.0 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG11306.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2722 PF10846.8 OAG11307.1 - 1.3e-08 34.3 0.3 1.3e-08 34.3 0.3 2.6 1 1 0 2 2 2 1 Protein of unknown function (DUF2722) Adeno_PX PF05829.12 OAG11307.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) RabGAP-TBC PF00566.18 OAG11309.1 - 1.6e-35 122.7 0.0 2.4e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EHN PF06441.12 OAG11310.1 - 2.5e-30 105.0 0.9 4.2e-30 104.3 0.9 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG11310.1 - 5.2e-09 36.1 0.3 3e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold E1-E2_ATPase PF00122.20 OAG11311.1 - 7.1e-36 123.4 7.6 1.2e-30 106.4 0.0 4.0 4 1 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG11311.1 - 2.5e-24 86.0 6.5 2.5e-24 86.0 6.5 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG11311.1 - 1.2e-18 68.2 0.1 7.1e-17 62.4 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG11311.1 - 2.6e-17 62.7 0.0 5.2e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG11311.1 - 4.2e-16 58.4 0.9 1.2e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG11311.1 - 2.1e-05 24.4 0.5 0.0013 18.5 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MarR_2 PF12802.7 OAG11311.1 - 0.12 12.3 0.0 4 7.4 0.0 2.8 3 0 0 3 3 3 0 MarR family Spore_IV_A PF09547.10 OAG11311.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Phage_holin_3_5 PF16085.5 OAG11311.1 - 1.2 9.3 4.7 25 5.0 1.5 2.5 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III p450 PF00067.22 OAG11315.1 - 1.6e-59 201.9 0.0 1.8e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HhH-GPD PF00730.25 OAG11316.1 - 3.6e-06 27.4 0.0 3.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Acetyltransf_1 PF00583.25 OAG11319.1 - 1.1e-08 35.3 0.0 3.6e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG11319.1 - 2.9e-08 34.0 0.0 4.2e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG11319.1 - 7.3e-07 29.2 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG11319.1 - 1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAG11319.1 - 1e-05 26.2 0.0 1.4e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG11319.1 - 0.052 13.7 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 OAG11319.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.19 OAG11320.1 - 4.5e-77 259.3 0.0 6.4e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG11320.1 - 4.7e-33 114.7 0.0 1.2e-32 113.4 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG11320.1 - 0.00037 19.7 0.1 0.00054 19.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG11320.1 - 0.015 14.6 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG11320.1 - 0.034 13.3 0.1 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 OAG11320.1 - 0.054 13.1 1.5 0.25 10.9 1.4 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG11320.1 - 0.063 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family AOX PF01786.17 OAG11321.1 - 5.9e-95 316.9 0.8 7.3e-95 316.6 0.8 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 OAG11321.1 - 0.12 12.2 0.0 1.6 8.5 0.0 2.2 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Acylphosphatase PF00708.18 OAG11322.1 - 1.7e-25 89.2 0.3 1.9e-25 89.1 0.3 1.0 1 0 0 1 1 1 1 Acylphosphatase VIT PF08487.10 OAG11322.1 - 0.0024 18.1 0.1 0.0027 17.9 0.1 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain PTA_PTB PF01515.19 OAG11322.1 - 0.093 12.0 0.1 0.14 11.4 0.1 1.3 1 1 0 1 1 1 0 Phosphate acetyl/butaryl transferase CH PF00307.31 OAG11323.1 - 0.022 14.9 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain TAF8_C PF10406.9 OAG11323.1 - 0.024 15.2 0.4 0.075 13.6 0.4 1.8 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term YopE_N PF09020.10 OAG11323.1 - 0.067 13.4 0.6 0.14 12.4 0.6 1.5 1 0 0 1 1 1 0 YopE, N terminal Cas_APE2256 PF09651.10 OAG11323.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) KAR9 PF08580.10 OAG11324.1 - 2.1e-146 489.3 28.2 2.1e-146 489.3 28.2 3.3 2 2 1 3 3 3 1 Yeast cortical protein KAR9 DUF2730 PF10805.8 OAG11324.1 - 0.22 11.7 4.7 0.24 11.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Laminin_II PF06009.12 OAG11324.1 - 1.4 8.9 7.4 3.4 7.7 0.4 3.3 3 0 0 3 3 3 0 Laminin Domain II PIG-L PF02585.17 OAG11325.1 - 2.9e-06 27.9 0.4 2.2e-05 25.1 0.4 2.1 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase DRIM PF07539.12 OAG11326.1 - 8.3e-182 605.8 0.4 8.3e-182 605.8 0.4 3.6 4 0 0 4 4 4 1 Down-regulated in metastasis HEAT_2 PF13646.6 OAG11326.1 - 0.00027 21.3 1.8 0.28 11.6 0.0 5.6 5 0 0 5 5 5 1 HEAT repeats Arm PF00514.23 OAG11326.1 - 0.012 15.6 1.5 2.1 8.5 0.3 4.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 OAG11326.1 - 0.057 12.7 10.1 0.57 9.4 0.8 4.8 4 1 0 4 4 4 0 V-ATPase subunit H Ipi1_N PF12333.8 OAG11326.1 - 0.073 13.7 0.0 7.1 7.3 0.0 4.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation BAR_3 PF16746.5 OAG11326.1 - 0.85 9.3 4.6 0.59 9.8 0.2 3.0 4 0 0 4 4 4 0 BAR domain of APPL family SDH_beta PF03315.15 OAG11327.1 - 0.098 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine dehydratase beta chain Glyco_hydro_cc PF11790.8 OAG11328.1 - 4.1e-45 154.2 0.4 7e-45 153.5 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SOG2 PF10428.9 OAG11328.1 - 2.7 7.1 11.1 3.5 6.7 11.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1772 PF08592.11 OAG11330.1 - 0.93 9.8 20.7 0.03 14.6 12.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Zn_clus PF00172.18 OAG11331.1 - 9.2e-08 32.1 8.6 1.4e-07 31.5 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG11331.1 - 0.014 14.2 0.8 0.02 13.7 0.8 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cullin PF00888.22 OAG11332.1 - 3.2e-201 670.2 10.8 4.7e-201 669.6 10.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG11332.1 - 4.4e-26 90.7 2.6 4.4e-26 90.7 2.6 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain Rrf2 PF02082.20 OAG11332.1 - 0.019 15.3 0.3 0.24 11.8 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator FerI PF08151.12 OAG11332.1 - 0.028 14.5 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 FerI (NUC094) domain zf-DNL PF05180.12 OAG11333.1 - 3.1e-29 100.7 1.0 4.3e-29 100.2 1.0 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 OAG11333.1 - 0.046 13.6 0.2 7.2 6.6 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 OAG11333.1 - 0.15 12.1 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1996 PF09362.10 OAG11334.1 - 5.8e-86 288.3 2.4 7.8e-86 287.9 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 OAG11334.1 - 4.4e-19 68.4 9.1 2.4e-18 66.1 9.1 2.4 1 0 0 1 1 1 1 WSC domain KRTAP PF11759.8 OAG11335.1 - 2 9.0 13.6 21 5.8 8.5 2.4 2 0 0 2 2 2 0 Keratin-associated matrix Lactamase_B_6 PF16661.5 OAG11336.1 - 1.9e-66 223.2 0.0 2.9e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 OAG11336.1 - 7e-40 137.0 0.1 7e-40 137.0 0.1 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 OAG11336.1 - 5e-19 68.6 0.0 1.6e-18 67.0 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 OAG11336.1 - 1.2e-11 44.3 0.0 2.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 OAG11336.1 - 0.017 15.1 0.5 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Fungal_trans_2 PF11951.8 OAG11337.1 - 8e-59 199.4 0.2 1.2e-58 198.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11337.1 - 3.7e-09 36.6 11.9 6.4e-09 35.8 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-HYPF PF07503.12 OAG11338.1 - 0.017 14.8 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 HypF finger ABC2_membrane PF01061.24 OAG11339.1 - 1.3e-46 158.7 35.9 4.2e-25 88.4 16.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAG11339.1 - 2.1e-37 128.7 0.0 1.4e-22 80.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG11339.1 - 8.7e-10 38.9 2.8 0.077 12.8 0.0 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG11339.1 - 8.3e-05 22.1 0.0 0.21 11.0 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAG11339.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 OAG11339.1 - 0.00016 22.3 0.1 0.00033 21.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG11339.1 - 0.00058 20.3 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG11339.1 - 0.0018 18.5 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG11339.1 - 0.0063 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 OAG11339.1 - 0.0087 15.1 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 OAG11339.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 OAG11339.1 - 0.02 15.1 0.1 24 5.2 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 OAG11339.1 - 0.037 13.6 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF4388 PF14332.6 OAG11339.1 - 0.04 14.2 0.0 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) cobW PF02492.19 OAG11339.1 - 0.12 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.11 OAG11339.1 - 0.19 11.5 1.4 0.72 9.6 0.8 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Isochorismatase PF00857.20 OAG11340.1 - 1.2e-13 51.7 0.0 4.5e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family SET PF00856.28 OAG11345.1 - 3.9e-13 50.1 0.0 2.4e-12 47.6 0.0 2.2 2 1 0 2 2 2 1 SET domain EamA PF00892.20 OAG11346.1 - 1.7e-23 83.3 33.5 1.1e-11 45.1 12.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family Glyco_hydro_61 PF03443.14 OAG11347.1 - 1.5e-62 211.2 0.3 1.8e-62 210.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CoA_trans PF01144.23 OAG11349.1 - 1e-102 342.1 0.4 4.6e-63 212.5 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Lectin_leg-like PF03388.13 OAG11350.1 - 5.1e-25 88.2 0.0 8.7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Neur_chan_memb PF02932.16 OAG11350.1 - 0.0056 16.8 0.1 0.0085 16.2 0.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.13 OAG11350.1 - 3.1 8.4 10.0 6.6 7.4 10.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Allexi_40kDa PF05549.11 OAG11350.1 - 8.8 5.8 7.8 0.52 9.8 1.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Band_7 PF01145.25 OAG11351.1 - 3.2e-21 76.1 5.5 3.2e-21 76.1 5.5 1.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Patatin PF01734.22 OAG11353.1 - 1.5e-12 48.1 0.0 6.6e-05 23.2 0.0 2.6 3 0 0 3 3 3 2 Patatin-like phospholipase CinA PF02464.17 OAG11355.1 - 1.7e-37 128.4 0.5 1.9e-37 128.2 0.5 1.0 1 0 0 1 1 1 1 Competence-damaged protein PLRV_ORF5 PF01690.17 OAG11355.1 - 0.098 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AA_permease_2 PF13520.6 OAG11357.1 - 1.3e-60 205.4 51.6 1.6e-60 205.1 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG11357.1 - 1.1e-14 53.9 50.7 5.6e-14 51.6 50.8 1.8 1 1 0 1 1 1 1 Amino acid permease Presenilin PF01080.17 OAG11357.1 - 0.0089 14.8 1.8 0.0089 14.8 1.8 1.9 2 0 0 2 2 2 1 Presenilin VID27 PF08553.10 OAG11358.1 - 3e-189 628.5 0.2 3.9e-189 628.1 0.2 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 OAG11358.1 - 7.5e-75 250.5 0.4 7.5e-75 250.5 0.4 2.5 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 OAG11358.1 - 2e-44 150.3 1.2 7.7e-44 148.4 0.6 2.1 2 0 0 2 2 2 1 VID27 PH-like domain SDA1 PF05285.12 OAG11358.1 - 0.75 9.2 8.0 1.5 8.2 8.0 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAG11358.1 - 0.89 7.7 9.0 1.5 7.0 9.0 1.2 1 0 0 1 1 1 0 Nop14-like family Adaptin_N PF01602.20 OAG11359.1 - 6.9e-135 450.6 8.0 8.1e-135 450.3 8.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG11359.1 - 4.6e-65 218.6 3.2 5.7e-61 205.3 0.5 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG11359.1 - 1.8e-17 63.5 1.8 1.3e-05 25.5 0.0 5.5 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.22 OAG11359.1 - 7.8e-14 50.6 4.2 0.0077 16.4 0.0 7.3 9 0 0 9 9 9 3 HEAT repeat Arm PF00514.23 OAG11359.1 - 0.00051 20.0 3.0 32 4.7 0.0 5.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 OAG11359.1 - 0.00082 19.0 0.2 0.9 9.1 0.0 3.7 3 1 1 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.6 OAG11359.1 - 0.0044 17.5 5.1 0.61 10.7 0.0 5.7 6 1 1 7 7 7 1 HEAT-like repeat UNC45-central PF11701.8 OAG11359.1 - 0.0077 16.2 0.6 1.7 8.6 0.0 3.0 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Sec7_N PF12783.7 OAG11359.1 - 0.16 11.9 1.6 0.32 10.9 0.3 2.4 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF5310 PF17237.2 OAG11360.1 - 2.4e-18 65.7 1.3 3e-18 65.4 1.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) DEK_C PF08766.11 OAG11361.1 - 0.12 12.4 0.2 0.37 10.7 0.2 2.0 1 1 0 1 1 1 0 DEK C terminal domain GREB1 PF15782.5 OAG11361.1 - 5 4.1 14.8 6.9 3.6 14.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_transf_20 PF00982.21 OAG11362.1 - 2.1e-200 666.4 0.0 2.5e-200 666.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 OAG11362.1 - 0.005 16.6 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain NFACT-C PF11923.8 OAG11363.1 - 9e-38 128.4 0.1 9e-38 128.4 0.1 3.5 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 OAG11363.1 - 1.8e-32 112.7 16.6 2.3e-31 109.1 16.6 2.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 OAG11363.1 - 2.6e-27 95.6 0.0 6.3e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain Clat_adaptor_s PF01217.20 OAG11364.1 - 5e-14 52.4 0.0 7.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain fn3_3 PF14686.6 OAG11366.1 - 9.5e-26 89.4 0.1 2.3e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 OAG11366.1 - 4.5e-23 81.9 0.6 1.2e-22 80.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 OAG11366.1 - 0.0023 18.2 0.0 0.0073 16.6 0.0 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain PepSY_2 PF13670.6 OAG11366.1 - 0.092 12.8 1.5 0.28 11.2 0.1 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Inositol_P PF00459.25 OAG11368.1 - 1.8e-61 208.1 0.0 2.3e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family SKG6 PF08693.10 OAG11369.1 - 2.1e-05 23.8 2.4 5e-05 22.6 2.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4381 PF14316.6 OAG11369.1 - 0.049 13.9 0.7 0.089 13.0 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) PAP1 PF08601.10 OAG11369.1 - 0.4 10.4 9.0 0.11 12.2 4.8 2.0 2 1 0 2 2 2 0 Transcription factor PAP1 AD PF09793.9 OAG11370.1 - 9.4e-25 86.6 0.4 1.3e-24 86.1 0.4 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Ribosomal_L27e PF01777.18 OAG11370.1 - 0.09 13.1 0.1 0.33 11.3 0.1 1.8 1 1 1 2 2 2 0 Ribosomal L27e protein family 6PGD PF00393.19 OAG11371.1 - 6.6e-128 426.1 0.0 8.4e-128 425.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG11371.1 - 6.9e-48 162.8 0.0 1e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG11371.1 - 0.027 14.7 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.22 OAG11372.1 - 1.3e-17 63.4 0.0 2.2e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWI-SNF_Ssr4 PF08549.10 OAG11373.1 - 1.5e-163 546.2 30.4 4.5e-150 501.7 12.9 3.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Phage_Mu_Gam PF07352.12 OAG11373.1 - 0.14 12.0 3.9 0.23 11.3 3.9 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Tyrosinase PF00264.20 OAG11374.1 - 2.4e-48 165.3 1.6 3.4e-48 164.9 1.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAG11374.1 - 3.3e-15 56.8 0.0 7.9e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Tyosinase C-terminal domain AIRC PF00731.20 OAG11375.1 - 8e-57 191.0 0.3 6e-56 188.1 0.0 2.1 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 OAG11375.1 - 8.6e-54 181.7 0.0 1.8e-53 180.7 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 OAG11375.1 - 1.1e-18 66.6 0.1 2.7e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 OAG11375.1 - 5.6e-05 22.8 0.0 0.00021 20.9 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 OAG11375.1 - 6.8e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AlaDh_PNT_C PF01262.21 OAG11375.1 - 9.4e-05 21.8 2.5 0.00011 21.5 1.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG11375.1 - 0.0063 15.9 0.3 0.016 14.6 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG11375.1 - 0.011 15.9 0.4 0.023 14.9 0.1 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 OAG11375.1 - 0.014 15.9 1.7 0.2 12.2 0.1 2.9 3 0 0 3 3 3 0 XdhC Rossmann domain ATP-grasp_3 PF02655.14 OAG11375.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain 3HCDH_N PF02737.18 OAG11375.1 - 0.024 14.5 0.3 0.064 13.1 0.3 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 OAG11375.1 - 0.047 14.5 0.2 0.12 13.2 0.2 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.6 OAG11375.1 - 0.063 13.2 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Ribosomal_L18 PF17135.4 OAG11376.1 - 2.4e-89 297.7 2.9 2.7e-89 297.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OAG11376.1 - 2.1e-05 25.2 0.3 8.9e-05 23.2 0.3 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TPT PF03151.16 OAG11377.1 - 1.7e-24 86.7 20.3 2.1e-24 86.4 20.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OAG11377.1 - 0.00012 21.4 22.5 0.00076 18.8 22.5 1.9 1 1 0 1 1 1 1 UAA transporter family NAD_binding_8 PF13450.6 OAG11378.1 - 9.2e-09 35.4 0.0 3.2e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG11378.1 - 9.5e-07 28.4 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAG11378.1 - 0.0026 17.0 0.2 0.014 14.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG11378.1 - 0.0036 16.6 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG11378.1 - 0.0053 16.1 0.3 0.0092 15.3 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG11378.1 - 0.0074 15.6 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG11378.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 OAG11378.1 - 0.027 14.0 0.0 0.058 13.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 OAG11378.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 OAG11378.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 OAG11378.1 - 0.088 12.8 0.5 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG11378.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAG11378.1 - 0.12 11.4 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Aldedh PF00171.22 OAG11379.1 - 1.8e-12 46.6 3.7 1.8e-05 23.4 0.0 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DinB PF05163.12 OAG11379.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 DinB family Glyco_hydro_16 PF00722.21 OAG11380.1 - 1.1e-41 142.2 3.5 2.2e-41 141.3 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Beta_elim_lyase PF01212.21 OAG11381.1 - 1.5e-36 126.2 0.0 1.9e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAG11381.1 - 4.5e-08 32.6 0.0 5.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAG11381.1 - 0.0016 17.5 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DBB PF14545.6 OAG11382.1 - 0.049 13.6 0.1 0.13 12.2 0.1 1.8 1 1 1 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, R3H PF01424.22 OAG11384.1 - 2.1e-10 40.4 0.0 8.9e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 R3H domain Rap1_C PF11626.8 OAG11384.1 - 0.076 13.1 0.0 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GatB_N PF02934.15 OAG11386.1 - 6.9e-98 327.4 0.0 9e-98 327.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OAG11386.1 - 5.9e-18 65.2 0.7 5.9e-18 65.2 0.7 1.6 2 0 0 2 2 2 1 GatB domain Glyco_transf_20 PF00982.21 OAG11388.1 - 3.7e-146 487.5 0.0 5.4e-146 487.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAG11388.1 - 4.2e-82 274.8 0.0 9.4e-82 273.6 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OAG11388.1 - 0.00031 20.6 0.0 0.0034 17.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OAG11388.1 - 0.12 11.9 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase PAP_assoc PF03828.19 OAG11389.1 - 0.00028 21.0 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG11389.1 - 0.0018 18.5 0.0 0.0037 17.5 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAG11389.1 - 0.099 12.7 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase UQ_con PF00179.26 OAG11390.1 - 4e-53 178.8 0.0 4.5e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG11390.1 - 0.004 16.9 0.0 0.005 16.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG11390.1 - 0.033 14.5 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OAG11390.1 - 0.045 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_1 PF00441.24 OAG11391.1 - 4e-24 85.5 0.1 7e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG11391.1 - 6.7e-23 81.5 0.3 1.2e-22 80.7 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG11391.1 - 3.3e-16 59.2 0.0 6.2e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG11391.1 - 2.7e-05 24.5 0.1 7.2e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_I PF00867.18 OAG11392.1 - 2.5e-31 107.9 1.3 8.4e-31 106.2 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OAG11392.1 - 4.1e-31 107.5 0.0 4.1e-31 107.5 0.0 2.2 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 OAG11392.1 - 7.7e-07 29.6 2.4 3.3e-06 27.6 0.0 2.7 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 OAG11392.1 - 2.9 7.4 7.7 1.5 8.3 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) DUF3824 PF12868.7 OAG11393.1 - 0.00011 22.9 51.1 0.00011 22.9 51.1 2.2 1 1 1 2 2 2 1 Domain of unknwon function (DUF3824) Acyl_transf_3 PF01757.22 OAG11394.1 - 1.4e-16 60.5 21.2 1.9e-16 60.1 21.2 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF1833 PF08875.11 OAG11394.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) SSXT PF05030.12 OAG11395.1 - 0.00042 19.9 5.7 0.014 15.0 5.7 2.7 1 1 0 1 1 1 1 SSXT protein (N-terminal region) FtsJ PF01728.19 OAG11396.1 - 1.8e-52 178.0 0.0 2.5e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 OAG11396.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG11396.1 - 0.14 12.9 0.0 0.46 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RTA1 PF04479.13 OAG11398.1 - 3.6e-64 216.2 10.4 4.3e-64 215.9 10.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans PF04082.18 OAG11399.1 - 6.8e-09 35.1 0.2 1.6e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11399.1 - 1.3e-06 28.4 7.7 2.1e-06 27.7 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAG11400.1 - 9.8e-59 199.3 0.0 3.6e-36 124.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 ALO PF04030.14 OAG11401.1 - 2e-08 34.4 1.7 0.0013 18.6 0.0 2.4 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OAG11401.1 - 1.7e-07 31.0 0.0 1.3e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Dioxygenase_C PF00775.21 OAG11402.1 - 1.1e-07 31.5 1.3 2.9e-07 30.1 0.2 2.1 2 1 0 2 2 2 1 Dioxygenase DUF4198 PF10670.9 OAG11402.1 - 0.086 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Aminotran_1_2 PF00155.21 OAG11403.1 - 1.6e-19 70.3 0.0 2.1e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Fungal_trans PF04082.18 OAG11404.1 - 3.4e-10 39.4 0.1 9e-10 38.0 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11404.1 - 1.7e-07 31.2 9.1 3e-07 30.5 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med4 PF10018.9 OAG11405.1 - 1.8e-32 112.6 9.0 2.9e-32 111.9 9.0 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Nucleo_P87 PF07267.11 OAG11405.1 - 0.14 11.0 6.7 0.16 10.8 6.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Med3 PF11593.8 OAG11405.1 - 7.2 5.7 16.7 1.4 8.0 11.8 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal EF-hand_7 PF13499.6 OAG11406.1 - 2e-24 85.8 7.2 4.8e-16 59.0 0.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OAG11406.1 - 8e-24 81.4 12.5 4.6e-08 32.1 0.1 4.9 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.6 OAG11406.1 - 3.9e-23 79.4 4.9 3.9e-06 26.3 0.1 5.3 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OAG11406.1 - 1.8e-17 61.9 11.5 3.7e-05 23.0 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 OAG11406.1 - 2.1e-14 53.1 10.5 2.6e-05 24.0 0.9 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 OAG11406.1 - 5.8e-08 32.6 6.5 0.0038 17.2 0.1 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OAG11406.1 - 0.00023 21.5 1.5 0.83 10.0 0.2 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OAG11406.1 - 0.0011 19.3 0.4 0.029 14.7 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain DUF1679 PF07914.11 OAG11406.1 - 0.059 12.2 0.3 2.5 6.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 OAG11406.1 - 0.59 10.0 4.9 1.4 8.8 0.0 3.5 4 1 0 4 4 4 0 EF hand His_biosynth PF00977.21 OAG11407.1 - 3.7e-47 160.7 1.3 1.5e-46 158.7 1.3 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 OAG11407.1 - 2.1e-23 83.1 0.0 3.3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OAG11407.1 - 3.6e-11 43.3 0.0 5.6e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAG11407.1 - 6.9e-07 29.1 0.0 2e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 OAG11407.1 - 0.0017 18.1 0.0 0.0046 16.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 RrnaAD PF00398.20 OAG11408.1 - 1.4e-64 217.8 0.0 1.8e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OAG11408.1 - 9.8e-08 32.6 0.0 1.9e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG11408.1 - 3.3e-06 27.7 0.0 7.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG11408.1 - 0.00035 20.4 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OAG11408.1 - 0.00037 20.4 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG11408.1 - 0.0024 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAG11408.1 - 0.0041 17.8 0.0 0.008 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG11408.1 - 0.0068 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG11408.1 - 0.048 13.0 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 OAG11408.1 - 0.06 12.9 0.0 1.1 8.8 0.0 2.2 1 1 1 2 2 2 0 Histone methylation protein DOT1 Ubie_methyltran PF01209.18 OAG11408.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_S4 PF00163.19 OAG11409.1 - 1.7e-12 48.0 2.5 2.8e-12 47.4 2.5 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 OAG11409.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain CHD5 PF04420.14 OAG11409.1 - 0.14 12.0 1.2 0.19 11.6 0.2 1.7 2 0 0 2 2 2 0 CHD5-like protein Cyclase PF04199.13 OAG11410.1 - 2.6e-14 53.6 0.0 3.5e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase GH131_N PF18271.1 OAG11412.1 - 1.6e-76 257.4 0.0 1.9e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Aminotran_5 PF00266.19 OAG11413.1 - 5.4e-24 84.8 0.0 8.1e-24 84.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 OAG11415.1 - 5.9e-29 101.1 20.5 8.9e-29 100.5 20.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4064 PF13273.6 OAG11415.1 - 4.2 7.7 9.1 1.6 9.0 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Bac_luciferase PF00296.20 OAG11416.1 - 8.6e-71 238.9 0.0 1.1e-70 238.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase AP_endonuc_2 PF01261.24 OAG11416.1 - 0.065 12.7 0.0 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Yippee-Mis18 PF03226.14 OAG11419.1 - 1e-19 70.7 0.0 1.3e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SCNM1_acidic PF15805.5 OAG11419.1 - 0.0029 17.3 3.5 0.0067 16.1 3.5 1.6 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 HECT_2 PF09814.9 OAG11419.1 - 0.063 12.1 0.0 4 6.2 0.0 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding FAM72 PF14976.6 OAG11419.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 FAM72 protein DUF678 PF05077.12 OAG11419.1 - 7.8 6.7 7.0 9.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF678) AA_permease PF00324.21 OAG11420.1 - 1.2e-63 215.4 21.2 5.1e-62 210.0 18.8 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 OAG11420.1 - 1.5e-25 89.9 19.2 1.8e-25 89.7 19.2 1.1 1 0 0 1 1 1 1 Amino acid permease DIM PF08194.12 OAG11420.1 - 0.034 14.3 0.3 0.64 10.3 0.0 3.2 2 0 0 2 2 2 0 DIM protein DEAD_2 PF06733.15 OAG11421.1 - 2.6e-57 193.3 0.2 4.3e-57 192.6 0.2 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 OAG11421.1 - 9.2e-49 165.7 1.2 5e-44 150.3 0.3 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 OAG11421.1 - 6.1e-43 147.0 0.0 1.8e-42 145.4 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 OAG11421.1 - 5.2e-05 23.3 0.0 0.0015 18.5 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG11421.1 - 0.00059 19.7 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 OAG11421.1 - 0.009 14.8 0.1 0.14 10.9 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 OAG11421.1 - 0.067 12.4 0.0 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OAG11421.1 - 0.17 11.3 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein FH2 PF02181.23 OAG11421.1 - 0.53 9.3 2.4 6 5.9 0.1 2.3 1 1 0 2 2 2 0 Formin Homology 2 Domain zf-RING_2 PF13639.6 OAG11422.1 - 6.9e-08 32.7 5.5 1.5e-07 31.6 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OAG11422.1 - 1.5e-05 25.1 2.6 6.2e-05 23.1 2.7 2.0 2 0 0 2 2 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 OAG11422.1 - 0.0019 18.0 3.7 0.0037 17.1 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG11422.1 - 0.0022 18.0 1.3 0.0051 16.8 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG11422.1 - 0.0025 18.0 4.1 0.0064 16.8 4.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 OAG11422.1 - 0.015 15.4 4.1 0.031 14.4 4.1 1.6 1 0 0 1 1 1 0 RING-variant domain XPC-binding PF09280.11 OAG11422.1 - 0.048 13.4 0.2 0.26 11.1 0.2 2.3 1 0 0 1 1 1 0 XPC-binding domain NIT PF08376.10 OAG11422.1 - 0.048 14.1 0.3 0.048 14.1 0.3 3.2 2 2 2 4 4 4 0 Nitrate and nitrite sensing PWI PF01480.17 OAG11422.1 - 0.093 13.1 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 PWI domain C1_1 PF00130.22 OAG11422.1 - 0.1 12.5 3.9 0.25 11.3 3.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 OAG11422.1 - 0.19 12.1 4.5 0.37 11.1 4.5 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 OAG11422.1 - 0.22 11.2 3.1 0.46 10.2 3.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RasGEF_N_2 PF14663.6 OAG11422.1 - 0.7 10.3 3.5 1.2e+02 3.1 0.0 4.1 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain zf-C3HC4_2 PF13923.6 OAG11422.1 - 0.71 9.8 4.5 1.5 8.7 4.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG11422.1 - 6 6.8 5.2 28 4.6 0.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ODC_AZ PF02100.17 OAG11424.1 - 6.9e-39 132.4 0.5 8.2e-39 132.1 0.5 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme FAD_binding_4 PF01565.23 OAG11425.1 - 6.4e-21 74.5 1.9 6.4e-21 74.5 1.9 2.0 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 OAG11425.1 - 1.5e-08 34.6 0.9 3.3e-08 33.5 0.9 1.6 1 0 0 1 1 1 1 Berberine and berberine like CFEM PF05730.11 OAG11426.1 - 9.9e-16 57.6 14.0 1.8e-15 56.8 14.0 1.5 1 0 0 1 1 1 1 CFEM domain NPL PF17800.1 OAG11427.1 - 2e-28 99.0 6.2 2e-28 99.0 6.2 3.0 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 OAG11427.1 - 3.5e-28 97.8 0.1 7.3e-28 96.7 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IMS PF00817.20 OAG11428.1 - 4.3e-41 140.4 0.0 7.8e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 OAG11428.1 - 3e-26 91.7 0.4 5.8e-26 90.7 0.4 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 OAG11428.1 - 2.6e-15 55.3 15.0 6.7e-06 25.4 0.4 5.0 5 0 0 5 5 5 3 Ubiquitin binding region IMS_C PF11799.8 OAG11428.1 - 4.6e-12 46.7 0.0 1.1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 OAG11428.1 - 2.6e-09 37.4 0.0 7.1e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAG11428.1 - 3.2e-05 24.2 0.0 8.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG11428.1 - 0.00024 21.0 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 OAG11428.1 - 0.012 15.9 0.4 0.099 13.0 0.1 2.7 2 0 0 2 2 2 0 IMS family HHH motif mCpol PF18182.1 OAG11428.1 - 0.022 15.1 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 minimal CRISPR polymerase domain DUF1805 PF08827.11 OAG11428.1 - 0.032 14.6 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) AT_hook PF02178.19 OAG11428.1 - 0.15 12.0 2.9 1.2 9.2 2.9 2.8 1 0 0 1 1 1 0 AT hook motif MgtE_N PF03448.17 OAG11428.1 - 0.35 11.5 1.6 23 5.6 0.2 3.5 3 0 0 3 3 3 0 MgtE intracellular N domain dCMP_cyt_deam_1 PF00383.23 OAG11430.1 - 2.3e-26 91.6 2.0 3.7e-26 91.0 2.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG11430.1 - 4.6e-10 39.4 0.2 7.2e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 OAG11430.1 - 0.00057 20.4 0.0 0.002 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 OAG11430.1 - 0.0034 17.1 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase DUF5484 PF17583.2 OAG11432.1 - 0.014 15.0 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5484) BRCT_2 PF16589.5 OAG11433.1 - 8.4e-07 29.3 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 OAG11433.1 - 0.064 13.2 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 twin BRCT domain Ank_2 PF12796.7 OAG11434.1 - 5.2e-07 30.2 0.0 3.4e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG11434.1 - 2.5e-05 24.8 0.0 0.00019 21.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG11434.1 - 0.00016 21.9 0.0 0.0021 18.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OAG11434.1 - 0.026 14.9 0.0 0.068 13.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 OAG11434.1 - 0.06 13.8 0.1 0.22 12.1 0.1 2.0 1 0 0 1 1 1 0 Ankyrin repeat CorA PF01544.18 OAG11435.1 - 2e-16 60.2 0.1 2.8e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Octopine_DH PF02317.17 OAG11435.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF2207 PF09972.9 OAG11435.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CorA PF01544.18 OAG11436.1 - 1.2e-43 149.5 2.4 2.6e-42 145.1 2.4 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 OAG11437.1 - 9.5e-32 110.3 25.3 9.5e-32 110.3 25.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG11437.1 - 0.017 14.0 4.8 0.04 12.8 3.5 2.0 2 0 0 2 2 2 0 MFS_1 like family CLN3 PF02487.17 OAG11437.1 - 0.17 10.9 2.3 1.1 8.3 0.7 2.4 2 1 0 2 2 2 0 CLN3 protein Acyltransferase PF01553.21 OAG11441.1 - 4.6e-26 91.0 0.0 8.8e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAG11441.1 - 5.1e-13 48.9 0.4 1.1e-12 47.9 0.4 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Podovirus_Gp16 PF05894.12 OAG11445.1 - 0.0084 15.6 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Podovirus DNA encapsidation protein (Gp16) DivIC PF04977.15 OAG11445.1 - 0.01 15.6 1.0 2.8 7.8 0.8 2.3 1 1 1 2 2 2 0 Septum formation initiator UBA_4 PF14555.6 OAG11445.1 - 0.011 15.6 0.2 0.02 14.7 0.2 1.4 1 0 0 1 1 1 0 UBA-like domain Exo_endo_phos PF03372.23 OAG11446.1 - 1e-07 31.7 0.1 3.6e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cytochrome-c551 PF10643.9 OAG11447.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Helo_like_N PF17111.5 OAG11448.1 - 1e-05 25.0 7.9 1.9e-05 24.2 6.3 2.0 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins CCDC84 PF14968.6 OAG11448.1 - 0.00065 19.4 0.7 0.00083 19.1 0.7 1.3 1 0 0 1 1 1 1 Coiled coil protein 84 URO-D PF01208.17 OAG11448.1 - 0.0062 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF2433 PF10360.9 OAG11448.1 - 0.033 14.3 2.8 0.06 13.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) DUF4372 PF14294.6 OAG11448.1 - 0.069 13.3 4.1 3.5 7.8 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) LMBR1 PF04791.16 OAG11448.1 - 0.12 11.2 2.5 0.14 11.0 2.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.11 OAG11448.1 - 0.14 12.4 4.6 1.8 8.9 0.3 3.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 OAG11448.1 - 0.52 10.6 12.4 0.19 12.0 0.5 3.3 2 2 1 3 3 3 0 Uncharacterized conserved protein DUF2120 PF09893.9 OAG11448.1 - 0.54 10.4 4.4 1.2 9.2 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Gp-FAR-1 PF05823.12 OAG11448.1 - 1.4 9.2 9.0 1.5 9.1 3.0 2.2 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Bcr-Abl_Oligo PF09036.10 OAG11448.1 - 1.9 8.6 9.9 0.55 10.3 0.3 3.8 3 2 2 5 5 5 0 Bcr-Abl oncoprotein oligomerisation domain Fib_alpha PF08702.10 OAG11448.1 - 6.4 7.0 14.6 10 6.3 1.1 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 OAG11449.1 - 2.5e-06 28.0 0.0 0.18 12.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG11449.1 - 0.00022 21.4 0.1 7.4 7.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG11449.1 - 0.0033 18.0 0.1 17 6.1 0.0 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ribosomal_S18 PF01084.20 OAG11451.1 - 1.6e-16 60.3 0.1 2.9e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.6 OAG11452.1 - 1.6e-07 31.4 1.8 0.32 11.2 0.0 6.5 7 0 0 7 7 7 2 PPR repeat family SPO22 PF08631.10 OAG11452.1 - 0.0012 18.3 0.0 0.18 11.2 0.0 2.6 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like DDE_Tnp_ISL3 PF01610.17 OAG11452.1 - 0.0045 16.7 0.6 0.0087 15.8 0.0 1.8 2 0 0 2 2 2 1 Transposase PPR PF01535.20 OAG11452.1 - 0.83 10.0 4.0 20 5.7 0.0 4.6 5 0 0 5 5 5 0 PPR repeat PS-DH PF14765.6 OAG11453.1 - 9e-64 215.5 0.0 1.5e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAG11453.1 - 5e-56 189.5 0.5 9.6e-56 188.5 0.5 1.5 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 OAG11453.1 - 1.6e-44 152.4 0.5 3.6e-44 151.2 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG11453.1 - 3.7e-41 141.7 0.0 6.2e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG11453.1 - 2.4e-39 134.0 0.9 4.4e-38 129.9 0.1 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAG11453.1 - 1.1e-19 71.0 0.0 4e-19 69.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG11453.1 - 2.6e-16 60.0 0.0 1.7e-15 57.4 0.0 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 OAG11453.1 - 1.6e-11 44.3 0.0 3.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OAG11453.1 - 2.9e-11 43.2 0.5 1.4e-09 37.7 0.1 2.8 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.26 OAG11453.1 - 4e-11 43.0 0.0 1.1e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG11453.1 - 4.5e-11 43.9 0.0 5e-10 40.5 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 OAG11453.1 - 6.1e-11 42.3 0.0 1.4e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG11453.1 - 3.7e-10 40.4 0.0 1.2e-09 38.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG11453.1 - 8.7e-10 39.1 0.0 2.9e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 OAG11453.1 - 1.2e-06 28.2 0.2 2.5e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 OAG11453.1 - 8.5e-06 26.0 0.2 3.3e-05 24.2 0.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 OAG11453.1 - 2.4e-05 23.8 0.0 5.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OAG11453.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 OAG11453.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 OAG11453.1 - 0.0031 16.9 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 OAG11453.1 - 0.032 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 OAG11453.1 - 0.043 13.7 0.2 0.14 12.0 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 OAG11454.1 - 2.2e-62 211.3 0.0 2.8e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 OAG11455.1 - 4.2e-21 75.1 0.2 7.7e-21 74.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BTB PF00651.31 OAG11460.1 - 1.7e-05 25.0 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain OTT_1508_deam PF14441.6 OAG11462.1 - 1.7e-18 66.4 0.9 3.9e-18 65.2 0.9 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase BTB PF00651.31 OAG11463.1 - 0.00019 21.6 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PGM_PMM_I PF02878.16 OAG11464.1 - 2e-39 134.5 0.1 4.9e-39 133.2 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OAG11464.1 - 1.5e-23 83.4 0.0 4.2e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OAG11464.1 - 7.1e-15 55.2 0.0 1.3e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OAG11464.1 - 2.9e-09 37.0 0.0 7.2e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Homeodomain PF00046.29 OAG11464.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain FA_desaturase PF00487.24 OAG11465.1 - 3.2e-25 89.4 26.5 4.6e-25 88.9 26.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAG11465.1 - 3e-08 33.7 0.0 6.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4592 PF15262.6 OAG11465.1 - 0.11 13.2 3.1 0.18 12.5 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) p450 PF00067.22 OAG11466.1 - 1.5e-52 178.9 0.0 2e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro2_C5 PF18565.1 OAG11468.1 - 9.1e-33 112.2 0.0 2.7e-32 110.7 0.0 1.9 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 DUF4982 PF16355.5 OAG11468.1 - 6.8e-26 90.0 2.6 1.5e-25 88.9 0.5 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4982) Glyco_hydro_2_C PF02836.17 OAG11468.1 - 2e-25 89.6 0.5 5.8e-25 88.0 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OAG11468.1 - 1.2e-14 54.6 0.0 2.5e-13 50.3 0.0 3.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OAG11468.1 - 1.8e-14 54.3 0.5 3.9e-14 53.2 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OAG11468.1 - 4.8e-05 23.9 0.0 0.0003 21.4 0.0 2.4 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 OAG11468.1 - 0.0016 18.7 0.2 0.0016 18.7 0.2 4.1 5 1 1 6 6 6 1 Invasin, domain 3 Glyco_hydro_61 PF03443.14 OAG11469.1 - 2.4e-09 37.5 0.0 2.7e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 OAG11470.1 - 5.9e-14 51.7 0.0 1.4e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11470.1 - 4.1e-05 23.6 8.8 7.9e-05 22.7 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 OAG11471.1 - 9.8e-08 31.4 0.9 1.7e-07 30.6 0.9 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 OAG11472.1 - 1.2e-21 77.0 18.3 1.2e-21 77.0 18.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2264 PF10022.9 OAG11473.1 - 1.4e-123 412.5 0.1 2e-123 412.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) SHNi-TPR PF10516.9 OAG11474.1 - 1.6e-12 46.6 1.2 4.2e-12 45.3 0.1 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 OAG11474.1 - 0.00047 20.4 7.2 0.05 13.9 1.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat CCDC-167 PF15188.6 OAG11474.1 - 0.00048 20.4 4.4 0.075 13.4 6.1 2.8 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 167 TPR_14 PF13428.6 OAG11474.1 - 1 10.4 3.8 21 6.3 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG11474.1 - 5.1 7.5 8.6 15 6.0 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 OAG11475.1 - 7.6e-48 162.6 0.0 1.1e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B HSP70 PF00012.20 OAG11476.1 - 5.5e-09 34.8 0.0 8.1e-09 34.2 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG11476.1 - 0.015 14.1 0.1 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Peptidase_M9 PF01752.17 OAG11476.1 - 0.022 14.0 0.2 0.045 13.0 0.2 1.5 1 0 0 1 1 1 0 Collagenase DASH_Dad2 PF08654.10 OAG11477.1 - 0.9 10.0 4.3 0.44 11.0 0.1 2.6 4 0 0 4 4 4 0 DASH complex subunit Dad2 TFIIIC_delta PF12657.7 OAG11479.1 - 1.4e-35 122.9 9.6 9.3e-34 117.0 2.0 3.0 3 0 0 3 3 3 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 OAG11479.1 - 1e-32 112.0 1.4 2.3e-32 111.0 1.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Cation_efflux PF01545.21 OAG11480.1 - 1.3e-43 149.1 8.0 1.3e-43 149.1 8.0 2.9 3 0 0 3 3 3 2 Cation efflux family Glyco_trans_4_4 PF13579.6 OAG11481.1 - 3.7e-06 27.5 0.6 7.2e-06 26.5 0.6 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 OAG11481.1 - 7.6e-06 26.4 0.0 4.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG11481.1 - 0.0033 17.5 0.6 0.0058 16.6 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAG11481.1 - 0.0052 16.3 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 SNF2_N PF00176.23 OAG11483.1 - 3.1e-58 197.2 0.0 4.7e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 OAG11483.1 - 1.3e-56 191.6 1.7 2.9e-56 190.5 1.7 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 OAG11483.1 - 1.6e-14 54.2 0.0 4.5e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG11483.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAG11483.1 - 0.011 15.0 0.0 0.055 12.6 0.0 2.0 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Cu-oxidase_2 PF07731.14 OAG11484.1 - 2e-44 150.6 4.9 3.9e-40 136.8 0.0 3.6 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG11484.1 - 9.3e-42 141.8 3.5 9.3e-42 141.8 3.5 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG11484.1 - 2.6e-37 128.4 0.5 3.1e-36 124.9 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase SAGA-Tad1 PF12767.7 OAG11486.1 - 0.022 14.5 0.9 0.045 13.5 0.9 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CG-1 PF03859.16 OAG11486.1 - 0.47 10.3 2.3 4.2 7.2 0.1 2.9 3 0 0 3 3 3 0 CG-1 domain DUF1485 PF07364.12 OAG11487.1 - 0.045 13.0 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M81 Zn_clus PF00172.18 OAG11488.1 - 5e-08 32.9 8.6 1.3e-07 31.7 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 OAG11488.1 - 8.1e-05 22.4 0.1 0.00023 21.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 OAG11488.1 - 0.099 11.6 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain F-box PF00646.33 OAG11489.1 - 0.00026 20.8 0.6 0.00086 19.1 0.6 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG11489.1 - 0.004 17.0 0.4 0.004 17.0 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 OAG11489.1 - 0.0089 15.9 0.2 0.02 14.8 0.2 1.6 1 0 0 1 1 1 1 F-box 2Fe-2S_thioredx PF01257.19 OAG11492.1 - 1.9e-61 206.1 0.5 2.4e-61 205.8 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Mo25 PF08569.11 OAG11493.1 - 2.1e-116 388.9 0.0 2.8e-116 388.5 0.0 1.1 1 0 0 1 1 1 1 Mo25-like Pkinase PF00069.25 OAG11493.1 - 3.5e-31 108.5 0.0 6.4e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11493.1 - 3.4e-11 42.9 0.0 7.6e-11 41.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAG11493.1 - 0.0014 18.6 0.1 0.33 10.8 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG11493.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OAG11493.1 - 0.033 13.0 0.0 0.059 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OAG11493.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OAG11493.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL muHD PF10291.9 OAG11494.1 - 7e-74 248.6 0.0 9.6e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 OAG11494.1 - 9.2e-11 41.9 0.0 2.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Laminin_II PF06009.12 OAG11494.1 - 0.0031 17.5 1.4 0.0067 16.4 1.4 1.6 1 0 0 1 1 1 1 Laminin Domain II DUF885 PF05960.11 OAG11494.1 - 0.19 11.4 5.3 0.086 12.5 2.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) HATPase_c PF02518.26 OAG11495.1 - 2.9e-26 92.2 0.1 5.9e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG11495.1 - 4.5e-19 68.3 0.1 1.1e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAG11495.1 - 1.9e-18 66.5 3.6 1.2e-10 41.6 0.5 3.5 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 OAG11495.1 - 2.5e-16 59.9 0.2 3.3e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain PAS PF00989.25 OAG11495.1 - 8.2e-08 32.2 0.0 0.0073 16.3 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OAG11495.1 - 1.4e-07 31.7 0.0 0.0013 19.0 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OAG11495.1 - 1.9e-07 31.3 0.1 4.9e-05 23.5 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 OAG11495.1 - 0.00093 19.2 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain BTB PF00651.31 OAG11496.1 - 0.21 11.8 0.0 0.5 10.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain PCI PF01399.27 OAG11497.1 - 0.0068 16.9 0.0 0.66 10.5 0.0 2.7 2 0 0 2 2 2 2 PCI domain PAN_1 PF00024.26 OAG11498.1 - 3.6e-05 23.7 2.7 0.0002 21.2 2.7 2.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OAG11498.1 - 0.0012 18.7 4.6 0.0028 17.5 4.6 1.6 1 0 0 1 1 1 1 PAN domain FMO-like PF00743.19 OAG11500.1 - 1e-11 44.0 0.0 2.3e-07 29.6 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG11500.1 - 1.6e-09 37.5 0.0 3.8e-07 29.7 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG11500.1 - 7.1e-09 35.3 0.1 3.1e-07 29.9 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG11500.1 - 2.6e-08 33.4 0.0 3.7e-05 23.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG11500.1 - 1.3e-05 25.3 0.1 2.7e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG11500.1 - 0.0043 17.1 0.0 1.5 8.9 0.0 3.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAG11500.1 - 0.0096 16.5 1.2 1.3 9.6 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG11500.1 - 0.016 15.2 0.5 0.65 10.0 0.2 3.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 OAG11500.1 - 0.051 13.2 1.4 0.38 10.3 1.7 2.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG11500.1 - 0.073 12.4 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAG11500.1 - 0.073 12.1 0.4 0.11 11.6 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 OAG11500.1 - 0.13 11.5 0.1 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG11500.1 - 0.22 10.5 0.3 0.48 9.5 0.3 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 OAG11500.1 - 0.26 11.2 0.5 0.47 10.3 0.5 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Beta-lactamase PF00144.24 OAG11501.1 - 3.7e-33 115.2 3.6 7.3e-33 114.2 3.6 1.4 1 1 0 1 1 1 1 Beta-lactamase SnoaL_2 PF12680.7 OAG11502.1 - 7.8e-05 23.3 0.1 0.00015 22.3 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG11502.1 - 0.00014 21.6 0.1 0.00024 20.9 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase VGPC1_C PF16799.5 OAG11502.1 - 0.18 11.8 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 SH3_9 PF14604.6 OAG11504.1 - 1.3e-09 37.8 0.0 2.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG11504.1 - 8.6e-07 28.5 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG11504.1 - 1.5e-05 24.5 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 OAG11504.1 - 0.011 15.9 5.7 0.019 15.0 5.7 1.4 1 0 0 1 1 1 0 Podoplanin LapA_dom PF06305.11 OAG11504.1 - 0.016 15.0 0.2 0.034 14.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Otopetrin PF03189.13 OAG11504.1 - 0.21 10.4 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Otopetrin CYYR1 PF10873.8 OAG11504.1 - 0.97 9.9 0.0 0.97 9.9 0.0 3.5 3 2 1 4 4 4 0 Cysteine and tyrosine-rich protein 1 AhpC-TSA PF00578.21 OAG11505.1 - 7.5e-30 103.4 0.0 9.7e-30 103.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 OAG11505.1 - 1.5e-13 50.3 0.0 2.9e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 OAG11505.1 - 1.6e-13 50.6 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Mito_carr PF00153.27 OAG11506.1 - 1.9e-58 194.4 6.5 1.1e-19 70.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Gly_rich PF12810.7 OAG11506.1 - 0.24 11.3 1.8 3.4 7.5 0.1 2.2 2 0 0 2 2 2 0 Glycine rich protein DUF2183 PF09949.9 OAG11507.1 - 1e-20 73.9 0.1 2.4e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Vma12 PF11712.8 OAG11508.1 - 0.51 10.4 1.5 1.9 8.6 0.4 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Abhydrolase_1 PF00561.20 OAG11509.1 - 1.4e-10 41.2 0.0 6.1e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG11509.1 - 0.016 14.5 0.0 0.13 11.5 0.0 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 OAG11509.1 - 0.21 11.7 0.0 0.53 10.4 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein Spore_coat_CotO PF14153.6 OAG11511.1 - 2.5 8.0 14.3 3.9 7.3 14.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4778 PF16008.5 OAG11511.1 - 3.8 7.5 9.4 6.6 6.7 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) PALP PF00291.25 OAG11513.1 - 6.5e-58 196.5 3.0 7.6e-58 196.2 3.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_Gly3P_dh_N PF01210.23 OAG11513.1 - 0.0073 16.3 0.1 1.1 9.2 0.1 2.2 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus EI24 PF07264.11 OAG11514.1 - 1.9e-10 41.3 11.0 2.6e-10 40.8 11.0 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Pyr_redox_2 PF07992.14 OAG11515.1 - 3.1e-69 233.4 7.8 3.1e-69 233.4 7.8 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAG11515.1 - 7.6e-40 135.6 1.3 1.9e-39 134.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAG11515.1 - 3.1e-22 78.9 11.3 9.7e-21 74.1 1.7 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG11515.1 - 1.9e-10 40.8 3.2 1.5e-05 25.1 0.9 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG11515.1 - 5e-09 36.0 0.7 5e-09 36.0 0.7 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG11515.1 - 1.4e-08 34.3 1.7 0.0044 16.3 0.3 3.1 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG11515.1 - 5.1e-08 32.4 11.8 2.5e-06 26.8 6.1 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG11515.1 - 1.8e-07 30.6 12.6 1.2e-06 27.9 4.4 3.8 4 0 0 4 4 4 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG11515.1 - 5.9e-07 29.0 6.5 0.0001 21.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG11515.1 - 2.7e-06 27.2 13.2 0.0049 16.5 0.3 3.8 4 0 0 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG11515.1 - 2e-05 23.5 15.1 0.00037 19.3 2.9 4.0 3 1 1 4 4 4 2 HI0933-like protein Thi4 PF01946.17 OAG11515.1 - 2.5e-05 23.7 4.7 2.5e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 OAG11515.1 - 5.4e-05 22.5 0.8 0.5 9.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAG11515.1 - 0.00022 20.6 9.9 0.35 10.1 0.0 3.4 3 0 0 3 3 3 3 FAD binding domain 3HCDH_N PF02737.18 OAG11515.1 - 0.027 14.3 0.8 0.027 14.3 0.8 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG11515.1 - 0.044 13.1 0.6 4.4 6.6 0.1 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAG11515.1 - 0.058 12.4 6.0 0.15 11.1 1.7 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 OAG11515.1 - 0.16 12.4 4.3 1.5 9.3 0.2 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding YbaB_DNA_bd PF02575.16 OAG11515.1 - 0.18 12.0 1.3 0.43 10.8 1.3 1.6 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family UDPG_MGDP_dh_N PF03721.14 OAG11515.1 - 1.3 8.5 5.5 0.9 9.1 0.3 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 OAG11515.1 - 2.5 6.8 7.4 0.67 8.7 1.7 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Drc1-Sld2 PF11719.8 OAG11516.1 - 1.3e-76 259.0 15.8 1.3e-76 259.0 15.8 1.9 1 1 1 2 2 2 1 DNA replication and checkpoint protein CSN8_PSD8_EIF3K PF10075.9 OAG11516.1 - 2.3e-19 69.8 0.0 6.6e-19 68.3 0.0 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Ribosomal_L11_N PF03946.14 OAG11517.1 - 1.2e-26 92.3 0.2 2e-26 91.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAG11517.1 - 4.1e-23 81.7 0.3 1e-22 80.4 0.3 1.7 1 1 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cytochrom_B561 PF03188.16 OAG11518.1 - 2.1e-17 63.5 4.6 2.1e-17 63.5 4.6 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 SPC12 PF06645.13 OAG11518.1 - 1.9 8.7 0.0 1.9 8.7 0.0 3.3 4 1 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Abhydrolase_6 PF12697.7 OAG11520.1 - 1.7e-17 64.8 0.1 2e-17 64.6 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG11520.1 - 3e-06 26.7 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OAG11520.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG11520.1 - 0.0075 15.9 0.0 0.01 15.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 OAG11520.1 - 0.099 12.3 0.0 0.43 10.3 0.0 1.8 1 1 1 2 2 2 0 PGAP1-like protein Abhydrolase_8 PF06259.12 OAG11520.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 OAG11520.1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TPT PF03151.16 OAG11521.1 - 2.4e-20 73.1 10.4 3.4e-20 72.6 10.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAG11521.1 - 8.1e-07 29.3 26.6 0.0013 18.9 3.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family Caldesmon PF02029.15 OAG11521.1 - 0.063 12.0 8.1 0.091 11.5 8.1 1.1 1 0 0 1 1 1 0 Caldesmon UAA PF08449.11 OAG11521.1 - 0.91 8.7 24.1 0.83 8.8 19.5 2.3 2 1 0 2 2 2 0 UAA transporter family CN_hydrolase PF00795.22 OAG11522.1 - 1.4e-32 113.1 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase STIMATE PF12400.8 OAG11523.1 - 1.6e-41 141.7 3.2 1.6e-41 141.7 3.2 1.5 2 0 0 2 2 2 1 STIMATE family FKBP_C PF00254.28 OAG11523.1 - 8.8e-31 106.1 0.0 1.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FAP PF07174.11 OAG11523.1 - 5.9 6.3 17.5 9.3 5.6 17.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GMC_oxred_C PF05199.13 OAG11524.1 - 3.1e-29 102.4 0.0 5.2e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG11524.1 - 3.7e-26 92.2 0.0 2.8e-23 82.7 0.0 2.7 2 1 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAG11524.1 - 2.4e-05 23.7 0.0 0.0058 15.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG11524.1 - 0.00024 20.5 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG11524.1 - 0.0016 18.7 0.1 0.0044 17.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG11524.1 - 0.038 13.1 0.1 0.25 10.4 0.0 2.2 2 1 1 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 OAG11524.1 - 0.12 11.6 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain His_Phos_2 PF00328.22 OAG11525.1 - 3.2e-28 99.2 0.0 5.4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pro-kuma_activ PF09286.11 OAG11527.1 - 5.7e-34 117.4 0.1 1.7e-33 115.9 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG11527.1 - 0.021 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 Subtilase family GMC_oxred_C PF05199.13 OAG11528.1 - 3.6e-20 73.0 0.0 2.6e-18 66.9 0.0 2.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG11528.1 - 4.9e-16 59.0 0.0 8.3e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Atg29_N PF18388.1 OAG11528.1 - 0.03 14.2 0.1 0.083 12.7 0.1 1.7 1 0 0 1 1 1 0 Atg29 N-terminal domain Abhydrolase_6 PF12697.7 OAG11529.1 - 1.2e-06 29.3 0.1 2.5e-06 28.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family T5orf172 PF10544.9 OAG11530.1 - 8.4e-12 45.5 0.0 1.6e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAG11530.1 - 9.9e-06 26.2 0.1 2.2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Zn_clus PF00172.18 OAG11531.1 - 1.6e-08 34.5 11.0 2.7e-08 33.8 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG11532.1 - 2.4e-23 82.6 0.4 3.4e-23 82.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG11532.1 - 5.8e-14 52.2 0.1 8e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG11532.1 - 7.2e-11 42.3 0.9 1.1e-10 41.7 0.9 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG11532.1 - 0.0012 18.1 0.4 0.0016 17.6 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG11532.1 - 0.039 14.0 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAG11533.1 - 3.9e-29 102.3 2.0 4.5e-29 102.1 2.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG11533.1 - 3.2e-05 24.1 0.2 9.5e-05 22.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG11533.1 - 0.0015 17.7 1.3 0.0018 17.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OAG11533.1 - 0.0063 15.8 0.0 0.0063 15.8 0.0 2.3 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 OAG11533.1 - 0.015 14.6 0.1 0.015 14.6 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG11533.1 - 0.044 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 OAG11533.1 - 0.051 13.1 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 OAG11533.1 - 0.12 12.6 0.1 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HET PF06985.11 OAG11534.1 - 3.9e-24 85.7 0.0 7.8e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 OAG11535.1 - 5.4e-50 170.1 0.2 6.9e-50 169.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG11535.1 - 4.7e-48 163.2 0.1 5.6e-48 163.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG11535.1 - 1.2e-08 35.1 0.2 2.2e-08 34.2 0.1 1.5 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 OAG11535.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG11535.1 - 0.09 12.2 0.1 0.16 11.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG11535.1 - 0.11 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BCAS2 PF05700.11 OAG11536.1 - 1.3e-50 171.9 4.1 1.6e-50 171.6 4.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Sld3_N PF18523.1 OAG11536.1 - 0.014 15.5 0.4 0.052 13.7 0.7 1.8 2 0 0 2 2 2 0 Sld3 N-terminal domain DUF5401 PF17380.2 OAG11536.1 - 0.016 13.3 5.1 0.019 13.1 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PipA PF07108.11 OAG11536.1 - 0.09 12.3 0.3 0.35 10.4 0.1 1.8 1 1 0 2 2 2 0 PipA protein Ceramidase_alk PF04734.13 OAG11537.1 - 2.8e-224 745.5 0.1 3.2e-224 745.2 0.1 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OAG11537.1 - 8.9e-60 201.4 0.1 1.4e-59 200.8 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal ErmC PF06308.11 OAG11537.1 - 0.06 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) Sugar_tr PF00083.24 OAG11538.1 - 3.7e-95 319.4 22.7 4.6e-95 319.1 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG11538.1 - 1.8e-24 86.3 61.5 4.2e-22 78.5 30.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily KAP_NTPase PF07693.14 OAG11539.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain PRK PF00485.18 OAG11539.1 - 0.0042 16.8 0.0 0.0055 16.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 OAG11539.1 - 0.0062 16.9 0.0 0.0072 16.7 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 OAG11539.1 - 0.0082 15.1 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 OAG11539.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 OAG11539.1 - 0.024 15.2 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG11539.1 - 0.036 14.2 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAG11539.1 - 0.04 13.6 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 OAG11539.1 - 0.061 12.5 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 OAG11539.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG11539.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Ldh_1_C PF02866.18 OAG11540.1 - 1.1e-45 155.6 0.0 1.5e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAG11540.1 - 7.1e-44 149.3 0.1 9.9e-44 148.9 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG11540.1 - 0.00015 20.8 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG11540.1 - 0.0049 17.3 0.0 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.18 OAG11541.1 - 1.9e-20 73.0 0.0 8.4e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG11542.1 - 1.2e-34 119.8 22.0 1.2e-34 119.8 22.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG11542.1 - 6.2e-11 41.8 17.6 5.2e-10 38.8 16.1 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter SAYSvFN PF10260.9 OAG11542.1 - 2 8.4 5.0 1.6 8.7 0.3 3.1 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) Zn_clus PF00172.18 OAG11543.1 - 5e-09 36.1 12.1 8.1e-09 35.5 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 OAG11544.1 - 5.2e-56 188.8 0.0 8e-56 188.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG11544.1 - 1.3e-20 73.5 0.0 1.5e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG11544.1 - 0.0056 16.9 0.2 0.029 14.5 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Iso_dh PF00180.20 OAG11545.1 - 1.2e-80 271.3 0.0 1.6e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pilus_CpaD PF09476.10 OAG11545.1 - 0.059 13.1 2.2 0.083 12.6 1.2 1.7 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) GRIN_C PF15235.6 OAG11545.1 - 0.066 13.4 0.9 0.17 12.1 0.4 1.9 1 1 1 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus SBF PF01758.16 OAG11546.1 - 6.9e-54 182.5 11.4 6.9e-54 182.5 11.4 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF4448 PF14610.6 OAG11546.1 - 8 6.2 6.2 25 4.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Rhodanese PF00581.20 OAG11547.1 - 8.1e-05 23.1 0.0 0.00011 22.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FMN_red PF03358.15 OAG11548.1 - 1.8e-22 79.8 0.0 2.6e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OAG11548.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold MFS_1 PF07690.16 OAG11549.1 - 9.1e-15 54.4 74.8 5.3e-13 48.6 46.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG11550.1 - 6e-11 41.9 0.3 5.6e-10 38.7 0.1 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11550.1 - 1.8e-08 34.4 12.2 4.9e-08 33.0 12.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 OAG11551.1 - 3.8e-12 46.9 0.0 6.8e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG11551.1 - 5.5e-05 22.1 0.0 0.15 10.8 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 OAG11551.1 - 0.0022 18.4 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OAG11551.1 - 0.0039 18.0 0.0 0.0082 17.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4913 PF16259.5 OAG11551.1 - 0.19 11.8 1.9 0.49 10.5 1.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4913) FAD_binding_3 PF01494.19 OAG11552.1 - 7.2e-18 64.9 0.1 1.7e-17 63.7 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG11552.1 - 2.5e-05 23.7 0.1 7.3e-05 22.1 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG11552.1 - 3.7e-05 23.0 0.2 7.4e-05 22.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG11552.1 - 4.1e-05 23.3 0.1 0.00029 20.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG11552.1 - 4.4e-05 23.6 0.2 0.00018 21.6 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG11552.1 - 0.00033 19.7 0.8 0.96 8.2 0.2 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG11552.1 - 0.0056 16.0 0.1 0.0084 15.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG11552.1 - 0.0097 14.7 0.2 0.017 13.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein DUF3038 PF11237.8 OAG11552.1 - 0.13 12.3 0.2 0.79 9.7 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3038) MFS_1 PF07690.16 OAG11553.1 - 5.9e-24 84.6 27.2 5.9e-24 84.6 27.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG11553.1 - 7.4e-11 41.6 10.0 7.4e-11 41.6 10.0 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG11553.1 - 7.5e-07 28.0 2.1 1.8e-06 26.7 2.1 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ADH_zinc_N_2 PF13602.6 OAG11554.1 - 2.5e-28 99.8 0.1 3.3e-28 99.4 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG11554.1 - 4.3e-15 55.8 0.2 6.8e-15 55.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 OAG11554.1 - 0.037 13.4 0.2 0.05 13.0 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme zf-RING_2 PF13639.6 OAG11555.1 - 5.4e-06 26.6 8.0 2e-05 24.8 8.0 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG11555.1 - 0.00013 21.9 4.3 0.00031 20.7 4.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OAG11555.1 - 0.00047 19.8 4.7 0.0011 18.6 4.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAG11555.1 - 0.00059 19.6 3.9 0.0015 18.4 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 OAG11555.1 - 0.0016 18.5 2.8 0.0037 17.3 2.8 1.5 1 0 0 1 1 1 1 KIAA1045 RING finger zf-ANAPC11 PF12861.7 OAG11555.1 - 0.023 14.7 2.0 0.074 13.1 2.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG11555.1 - 0.049 13.9 5.0 0.14 12.5 5.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG11555.1 - 0.062 13.3 7.6 0.14 12.1 7.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3H2C3 PF17122.5 OAG11555.1 - 0.091 12.8 2.7 0.73 9.9 1.4 3.0 2 0 0 2 2 2 0 Zinc-finger Prok-RING_1 PF14446.6 OAG11555.1 - 0.13 12.2 2.0 0.42 10.6 2.0 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 OAG11555.1 - 0.15 11.9 5.3 0.53 10.2 5.3 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAG11555.1 - 0.33 10.9 4.4 0.87 9.5 4.4 1.7 1 0 0 1 1 1 0 PHD-finger DnaJ PF00226.31 OAG11557.1 - 2.5e-05 24.3 0.0 7.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain FYVE PF01363.21 OAG11557.1 - 0.023 14.8 4.4 0.035 14.2 0.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger THOC2_N PF16134.5 OAG11557.1 - 4.9 5.7 7.8 6.4 5.3 7.8 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Presenilin PF01080.17 OAG11557.1 - 6.1 5.5 7.8 8.6 5.0 7.8 1.4 1 0 0 1 1 1 0 Presenilin Acetyltransf_1 PF00583.25 OAG11559.1 - 4.9e-10 39.7 0.0 8e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG11559.1 - 2.5e-09 37.4 0.0 3.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG11559.1 - 4.5e-08 33.2 0.0 3.8e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG11559.1 - 9e-08 32.0 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 OAG11559.1 - 1.3e-07 31.6 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAG11559.1 - 4.1e-05 23.3 0.0 6.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_3 PF13302.7 OAG11559.1 - 0.045 14.4 0.0 0.37 11.5 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG11559.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 OAG11559.1 - 0.078 13.0 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF4434 PF14488.6 OAG11559.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Gly_acyl_tr_C PF08444.10 OAG11559.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region p450 PF00067.22 OAG11560.1 - 5e-47 160.7 0.0 6.9e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 OAG11561.1 - 2.5e-06 26.6 0.3 5.3e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Y_phosphatase3 PF13350.6 OAG11563.1 - 2.5e-47 161.8 0.0 2.8e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Pmp3 PF01679.17 OAG11563.1 - 0.0014 18.8 0.3 0.0024 18.0 0.3 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Penicillinase_R PF03965.16 OAG11563.1 - 0.039 14.3 0.0 0.33 11.3 0.0 2.3 3 0 0 3 3 3 0 Penicillinase repressor Y_phosphatase2 PF03162.13 OAG11563.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAG11563.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3328 PF11807.8 OAG11565.1 - 5.4e-30 104.8 0.4 6.9e-30 104.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Bys1 PF04681.12 OAG11566.1 - 6.2e-06 26.2 0.4 7.5e-06 26.0 0.4 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NmrA PF05368.13 OAG11567.1 - 3.2e-22 79.2 0.0 4.3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG11567.1 - 1.4e-17 64.2 0.0 3.7e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG11567.1 - 0.00019 20.9 0.1 0.0085 15.6 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG11567.1 - 0.0002 21.6 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAG11567.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 OAG11567.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG11567.1 - 0.021 15.4 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 OAG11567.1 - 0.058 13.8 0.0 0.092 13.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.18 OAG11568.1 - 1.2e-05 25.3 8.4 2.8e-05 24.1 8.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CEBP_ZZ PF16366.5 OAG11568.1 - 0.089 13.0 0.1 0.089 13.0 0.1 2.4 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF3328 PF11807.8 OAG11569.1 - 7.3e-20 71.7 0.7 1.2e-19 71.0 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_114 PF03537.13 OAG11570.1 - 8.3e-49 166.0 0.0 9.2e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Glyco_hydro_97 PF10566.9 OAG11570.1 - 0.16 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 97 F-box PF00646.33 OAG11572.1 - 0.052 13.4 0.9 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 OAG11572.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box KxDL PF10241.9 OAG11572.1 - 0.14 12.5 1.4 0.23 11.7 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF2373 PF10180.9 OAG11573.1 - 5e-20 71.1 0.1 1e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Hira PF07569.11 OAG11573.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split Bcr-Abl_Oligo PF09036.10 OAG11573.1 - 0.12 12.4 2.0 0.37 10.8 2.0 1.8 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF1682 PF07946.14 OAG11573.1 - 4.3 6.5 9.8 9.7 5.3 9.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) Proteasome PF00227.26 OAG11574.1 - 3.6e-50 170.1 0.0 4.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG11574.1 - 5.2e-13 48.4 0.3 8.3e-13 47.8 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidase_5 PF05382.13 OAG11574.1 - 0.085 12.8 0.0 3.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase zf-RING_2 PF13639.6 OAG11578.1 - 4.1e-12 46.2 3.1 6.5e-12 45.6 3.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG11578.1 - 1.9e-06 27.8 1.8 3.8e-06 26.8 1.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG11578.1 - 1.9e-06 27.6 3.9 3.2e-06 26.9 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG11578.1 - 5.9e-06 26.0 2.8 1e-05 25.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG11578.1 - 6.6e-05 22.6 1.1 0.00013 21.7 0.7 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OAG11578.1 - 0.0001 22.5 0.8 0.00024 21.3 0.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAG11578.1 - 0.00014 21.7 2.5 0.00023 21.0 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG11578.1 - 0.00044 20.2 3.0 0.00073 19.4 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-TFIIIC PF12660.7 OAG11578.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Prok-RING_4 PF14447.6 OAG11578.1 - 0.0037 17.1 4.8 0.049 13.5 5.4 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG11578.1 - 0.009 16.1 3.5 0.017 15.2 3.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OAG11578.1 - 0.021 14.6 1.9 0.044 13.6 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OAG11578.1 - 0.028 14.5 0.7 0.061 13.4 0.7 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OAG11578.1 - 0.033 14.0 2.0 0.059 13.2 2.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3552 PF12072.8 OAG11578.1 - 0.57 9.6 18.3 0.013 14.9 11.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) zf-C3HC4_5 PF17121.5 OAG11578.1 - 0.62 10.0 4.8 2 8.4 4.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FAM76 PF16046.5 OAG11578.1 - 2.2 7.5 9.2 0.73 9.1 0.8 2.2 2 0 0 2 2 2 0 FAM76 protein PLAC8 PF04749.17 OAG11579.1 - 2.4e-21 76.6 20.5 2.9e-21 76.3 20.5 1.1 1 0 0 1 1 1 1 PLAC8 family Methyltransf_34 PF11312.8 OAG11581.1 - 2e-78 263.8 0.0 2.4e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase GrpB PF04229.14 OAG11582.1 - 3.6e-41 141.0 0.0 5.1e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 GrpB protein Acetyltransf_3 PF13302.7 OAG11582.1 - 2.1e-20 73.8 0.0 1e-19 71.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG11582.1 - 2e-05 24.8 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG11582.1 - 0.0063 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG11582.1 - 0.039 14.1 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAG11582.1 - 0.081 12.5 0.0 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase NAD_binding_10 PF13460.6 OAG11583.1 - 2.5e-15 56.8 0.0 3e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG11583.1 - 0.0066 15.9 0.0 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG11583.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Ten1 PF12658.7 OAG11585.1 - 4.6e-35 120.2 0.0 5.1e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 OAG11585.1 - 1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Snf7 PF03357.21 OAG11586.1 - 1.2e-39 135.7 15.7 1.2e-39 135.7 15.7 2.0 2 0 0 2 2 2 2 Snf7 NuA4 PF09340.10 OAG11586.1 - 0.15 11.9 0.3 0.15 11.9 0.3 2.2 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 DUF3138 PF11336.8 OAG11586.1 - 0.24 10.0 8.1 4.2 5.9 7.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Fmp27_WPPW PF10359.9 OAG11586.1 - 4.6 6.0 11.9 5.6 5.7 11.7 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Forkhead PF00250.18 OAG11587.1 - 8.2e-25 86.9 0.6 1.4e-24 86.1 0.6 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OAG11587.1 - 6.2e-09 36.1 0.0 1.7e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG11587.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain 2OG-FeII_Oxy_3 PF13640.6 OAG11588.1 - 4.4e-08 33.9 0.0 9.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OAG11588.1 - 0.078 13.5 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SKG6 PF08693.10 OAG11590.1 - 0.14 11.6 8.4 0.058 12.8 5.4 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SH2_2 PF14633.6 OAG11591.1 - 4.7e-79 264.8 0.1 4.7e-79 264.8 0.1 2.1 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 OAG11591.1 - 2.9e-36 124.5 0.2 1.3e-35 122.4 0.0 2.3 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 OAG11591.1 - 1.3e-33 115.8 0.2 4.7e-33 114.0 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 OAG11591.1 - 6.1e-24 84.4 0.0 1.8e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 OAG11591.1 - 2.9e-15 56.6 27.3 2.9e-15 56.6 27.3 4.0 4 1 0 4 4 4 1 Acidic N-terminal SPT6 SH2 PF00017.24 OAG11591.1 - 1.4e-05 25.1 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 OAG11591.1 - 8e-05 23.5 0.3 8e-05 23.5 0.3 3.0 3 1 0 3 3 3 1 HHH domain S1 PF00575.23 OAG11591.1 - 0.026 14.9 2.1 0.031 14.6 0.0 2.3 3 0 0 3 3 3 0 S1 RNA binding domain POTRA_1 PF08478.10 OAG11591.1 - 0.036 14.4 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 POTRA domain, FtsQ-type Tex_YqgF PF16921.5 OAG11591.1 - 0.05 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Tex protein YqgF-like domain Pkinase PF00069.25 OAG11592.1 - 9.3e-65 218.6 0.0 1.1e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11592.1 - 2.7e-38 131.8 0.0 3.7e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG11592.1 - 0.0017 17.3 0.0 0.0041 16.1 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG11592.1 - 0.0018 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAG11592.1 - 0.0058 16.0 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OAG11592.1 - 0.04 13.8 0.0 0.17 11.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAG11592.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 OAG11592.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase MSA-2c PF12238.8 OAG11592.1 - 4.6 7.2 6.4 5 7.1 4.8 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c RIG-I_C PF18119.1 OAG11593.1 - 0.034 14.2 0.1 0.044 13.8 0.1 1.2 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain Fungal_trans_2 PF11951.8 OAG11595.1 - 5.2e-10 38.7 0.0 1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11595.1 - 1.4e-05 25.1 9.2 2.6e-05 24.3 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDH-cyt PF16010.5 OAG11596.1 - 1.4e-51 174.8 1.4 1.4e-51 174.8 1.4 2.3 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 OAG11596.1 - 1.4e-28 100.2 0.0 2e-27 96.4 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG11596.1 - 2e-21 77.1 0.7 4e-21 76.1 0.7 1.5 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 OAG11596.1 - 4.5e-11 42.5 10.4 9.9e-11 41.4 10.4 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_oxidored PF12831.7 OAG11596.1 - 1.2e-05 24.9 1.6 0.00041 19.8 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG11596.1 - 2.2e-05 23.4 0.2 0.00011 21.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG11596.1 - 3.4e-05 23.2 0.1 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG11596.1 - 0.0001 21.5 2.0 0.0011 18.2 0.5 2.7 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 OAG11596.1 - 0.00073 18.7 0.0 0.0016 17.6 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 OAG11596.1 - 0.0046 16.1 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG11596.1 - 0.006 16.8 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG11596.1 - 0.013 14.8 0.6 0.072 12.3 0.9 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG11596.1 - 0.021 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAG11596.1 - 0.028 13.7 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 Thi4 family SPOC PF07744.13 OAG11598.1 - 4e-20 72.3 0.0 6.8e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 OAG11598.1 - 4.2e-17 62.6 0.1 7.7e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 OAG11598.1 - 3.8e-09 36.3 13.9 6.6e-09 35.5 13.9 1.4 1 0 0 1 1 1 1 PHD-finger ArfGap PF01412.18 OAG11600.1 - 1.4e-40 138.0 1.0 2.1e-40 137.4 1.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 OAG11600.1 - 0.045 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain GBS_Bsp-like PF08481.10 OAG11600.1 - 1.7 8.8 3.4 0.59 10.3 0.2 1.7 2 0 0 2 2 2 0 GBS Bsp-like repeat Hemerythrin PF01814.23 OAG11601.1 - 2.1e-06 28.4 5.1 3e-06 27.9 5.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain BSD PF03909.17 OAG11602.1 - 6.3e-19 67.7 1.7 1.1e-18 66.9 1.7 1.4 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 OAG11602.1 - 8.9 6.2 6.6 1.4 8.9 2.4 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ran-binding PF05508.11 OAG11603.1 - 6.1e-115 383.5 0.0 7.4e-115 383.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 OAG11604.1 - 1.6e-41 142.0 0.0 2.6e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG11604.1 - 7.2e-30 103.6 0.0 1.8e-29 102.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG11604.1 - 1.7e-06 28.3 0.1 5.9e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG11604.1 - 0.011 15.8 0.0 0.053 13.6 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF572 PF04502.13 OAG11605.1 - 5e-68 230.2 0.8 5.6e-68 230.0 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) RSN1_7TM PF02714.15 OAG11606.1 - 1.8e-84 283.3 18.8 1.8e-84 283.3 18.8 2.5 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG11606.1 - 1.5e-45 154.7 2.2 1.5e-45 154.7 2.2 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG11606.1 - 8.2e-30 104.3 0.2 1.4e-29 103.5 0.2 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAG11606.1 - 1.3e-21 76.6 0.2 3.4e-21 75.2 0.2 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 OAG11606.1 - 0.067 13.0 0.0 31 4.5 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3377 PF11857.8 OAG11606.1 - 0.16 11.9 2.0 1.2 9.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) WSC PF01822.19 OAG11608.1 - 1e-51 173.1 48.4 6.1e-19 68.0 14.1 3.5 3 0 0 3 3 3 3 WSC domain peroxidase PF00141.23 OAG11608.1 - 6.3e-15 55.5 0.1 1.6e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 Peroxidase C2 PF00168.30 OAG11609.1 - 6.3e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain Ribosomal_S15 PF00312.22 OAG11610.1 - 2.6e-24 85.2 0.3 8e-24 83.7 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 OAG11611.1 - 1.1e-26 93.4 0.1 4.5e-15 55.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OAG11611.1 - 3e-09 38.1 14.5 7.5e-09 36.8 14.5 1.7 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus EAF PF09816.9 OAG11612.1 - 3.5e-15 56.2 0.6 7.1e-15 55.2 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Chordopox_G3 PF06129.12 OAG11612.1 - 0.25 12.1 0.1 0.43 11.3 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Bys1 PF04681.12 OAG11614.1 - 0.00041 20.3 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein DUF386 PF04074.12 OAG11614.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 YhcH/YjgK/YiaL Pkinase PF00069.25 OAG11615.1 - 3.4e-15 56.1 0.4 8.4e-08 31.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11615.1 - 5e-06 26.0 0.0 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_2_N PF02837.18 OAG11616.1 - 2.4e-13 50.4 0.2 7.8e-13 48.7 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OAG11616.1 - 9.3e-12 45.6 0.1 2.6e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 OAG11616.1 - 1.2e-10 41.0 0.1 3.3e-10 39.6 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.6 OAG11616.1 - 0.00022 21.8 2.6 0.0004 20.9 1.3 2.1 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Cadherin-like PF12733.7 OAG11616.1 - 1.3 9.6 3.3 2.9 8.5 0.0 2.8 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain Acetyltransf_3 PF13302.7 OAG11617.1 - 3.6e-15 56.8 0.0 5.9e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG11617.1 - 5.8e-14 52.3 0.1 2.3e-13 50.4 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG11617.1 - 1.4e-06 28.6 0.0 2.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAG11617.1 - 3.3e-06 26.9 0.0 0.00034 20.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG11617.1 - 0.00015 22.0 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG11617.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG11617.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF5645 PF18713.1 OAG11619.1 - 0.035 14.4 0.1 0.063 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) F-box-like_2 PF13013.6 OAG11619.1 - 0.13 12.2 0.4 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like domain Pro-kuma_activ PF09286.11 OAG11620.1 - 1.6e-33 116.0 0.2 3.1e-33 115.0 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG11620.1 - 1.3e-05 24.6 0.1 2.8e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.16 OAG11622.1 - 2.5e-35 122.1 25.9 2.5e-35 122.1 25.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Lipocalin_2 PF08212.12 OAG11623.1 - 4.4e-14 52.6 0.0 5.4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OAG11623.1 - 0.0003 21.0 0.0 0.00043 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family UQ_con PF00179.26 OAG11624.1 - 6.3e-20 71.3 0.0 1.5e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SDA1 PF05285.12 OAG11624.1 - 2.5 7.4 9.1 3.9 6.8 9.1 1.2 1 0 0 1 1 1 0 SDA1 Dor1 PF04124.12 OAG11625.1 - 1.1e-51 175.5 0.5 1e-40 139.5 1.6 2.2 2 0 0 2 2 2 2 Dor1-like family DUF4208 PF13907.6 OAG11625.1 - 0.0036 17.7 0.2 0.028 14.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) WT1 PF02165.15 OAG11625.1 - 0.03 13.5 0.3 0.052 12.8 0.3 1.3 1 0 0 1 1 1 0 Wilm's tumour protein COG5 PF10392.9 OAG11625.1 - 0.29 11.3 7.5 0.54 10.4 2.4 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Cpn60_TCP1 PF00118.24 OAG11627.1 - 7.3e-172 572.4 1.6 8.3e-172 572.2 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Solute_trans_a PF03619.16 OAG11628.1 - 1.4e-59 201.8 9.3 1.7e-59 201.5 9.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Docking PF08990.11 OAG11631.1 - 1e-05 25.0 39.0 4.7 6.9 0.2 11.6 11 1 1 12 12 12 7 Erythronolide synthase docking Phage_GP20 PF06810.11 OAG11631.1 - 0.00085 19.2 0.3 16 5.2 0.1 4.0 1 1 2 4 4 4 1 Phage minor structural protein GP20 RNA_polI_A14 PF08203.11 OAG11631.1 - 0.027 15.2 16.8 8.2 7.2 0.7 5.4 1 1 1 3 3 3 0 Yeast RNA polymerase I subunit RPA14 DUF1515 PF07439.11 OAG11631.1 - 0.082 12.9 0.2 0.75 9.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) LRR_11 PF18831.1 OAG11631.1 - 1.9 8.1 23.8 80 2.9 0.0 9.9 11 1 1 12 12 12 0 Leucine-rich repeat DUF3328 PF11807.8 OAG11632.1 - 9.8e-24 84.4 5.4 1.2e-23 84.1 5.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) His_Phos_2 PF00328.22 OAG11633.1 - 2.2e-41 142.5 0.0 2.8e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 OAG11635.1 - 8.5e-37 126.9 31.6 1.2e-36 126.3 31.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_2 PF03446.15 OAG11636.1 - 3.9e-33 114.9 0.4 6.2e-33 114.2 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG11636.1 - 3.5e-21 75.7 0.0 5.8e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CMD PF02627.20 OAG11637.1 - 1e-12 47.9 0.0 8.2e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Lactamase_B PF00753.27 OAG11637.1 - 9.1e-09 35.6 2.5 2.8e-08 34.0 2.5 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG11637.1 - 0.006 16.1 0.3 0.019 14.5 0.2 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NAD_binding_2 PF03446.15 OAG11638.1 - 7.4e-34 117.2 0.0 1e-33 116.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG11638.1 - 8.7e-21 74.4 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG11638.1 - 0.0041 17.7 0.0 0.008 16.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAG11638.1 - 0.042 13.9 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ER PF01133.17 OAG11638.1 - 0.042 13.9 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Enhancer of rudimentary OCD_Mu_crystall PF02423.15 OAG11638.1 - 0.052 12.5 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 OAG11638.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMD PF02627.20 OAG11639.1 - 1.4e-18 66.7 0.1 2.3e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Fungal_trans PF04082.18 OAG11640.1 - 3.4e-12 45.9 0.8 7.4e-11 41.6 0.8 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG11640.1 - 0.00041 20.7 1.9 0.00041 20.7 1.9 2.6 1 1 1 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG11640.1 - 0.0024 18.6 2.0 0.0096 16.7 2.0 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAG11640.1 - 0.06 13.3 3.1 0.16 11.9 3.1 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type ADH_N PF08240.12 OAG11641.1 - 2.8e-17 62.6 0.7 7.6e-17 61.2 0.7 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG11641.1 - 5.2e-15 55.6 0.1 8.4e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 OAG11641.1 - 0.12 12.5 0.1 0.37 11.0 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Lactamase_B PF00753.27 OAG11642.1 - 1.7e-06 28.2 5.5 1.5e-05 25.1 5.5 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG11642.1 - 5.3e-05 22.8 1.0 0.00023 20.8 1.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Tachylectin PF14517.6 OAG11642.1 - 0.041 13.4 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Tachylectin His_Phos_1 PF00300.22 OAG11643.1 - 0.2 11.3 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) APG6_N PF17675.1 OAG11644.1 - 0.015 15.8 4.1 0.023 15.2 4.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1974 PF09317.11 OAG11644.1 - 0.046 13.3 1.0 0.065 12.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) HTH_37 PF13744.6 OAG11644.1 - 0.046 13.7 0.4 0.1 12.6 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ank_2 PF12796.7 OAG11645.1 - 1.6e-36 124.7 0.2 3.8e-11 43.4 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OAG11645.1 - 1.9e-31 107.1 1.5 2.1e-05 24.7 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OAG11645.1 - 6.4e-28 96.4 10.1 6.4e-07 29.5 0.1 6.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG11645.1 - 1.7e-24 85.9 0.8 1.2e-07 32.1 0.0 5.6 1 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG11645.1 - 2.4e-20 70.4 0.8 4.9e-05 23.4 0.0 7.2 7 1 0 7 7 7 4 Ankyrin repeat Choline_sulf_C PF12411.8 OAG11645.1 - 0.12 12.1 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal PARP PF00644.20 OAG11646.1 - 1.6e-61 207.3 0.0 2.7e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OAG11646.1 - 1.6e-43 148.1 0.1 2.4e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OAG11646.1 - 4.7e-18 65.0 1.1 1.1e-17 63.9 1.1 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 OAG11646.1 - 9.4e-08 32.3 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG11646.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain PhoD PF09423.10 OAG11648.1 - 4e-114 381.3 4.8 5e-114 381.0 4.8 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAG11648.1 - 8.7e-34 115.9 0.0 2e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OAG11648.1 - 1.1e-05 26.0 0.7 3e-05 24.5 0.7 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 OAG11648.1 - 0.088 13.3 4.9 0.18 12.3 3.6 2.0 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.26 OAG11649.1 - 5.7e-13 49.0 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG11649.1 - 1.2e-05 25.1 0.0 3.7e-05 23.6 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG11649.1 - 2e-05 25.6 0.0 9.5e-05 23.5 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Med7 PF05983.11 OAG11650.1 - 3.8e-53 180.4 0.3 4.9e-53 180.1 0.3 1.1 1 0 0 1 1 1 1 MED7 protein PKcGMP_CC PF16808.5 OAG11650.1 - 1.8 8.5 5.4 0.98 9.3 1.7 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Methyltransf_23 PF13489.6 OAG11651.1 - 7.7e-23 81.1 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG11651.1 - 1.1e-13 51.7 0.0 3.3e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG11651.1 - 1.6e-12 47.9 0.0 3.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG11651.1 - 4.5e-09 36.9 0.0 3.7e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG11651.1 - 1.1e-08 35.1 0.0 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 OAG11651.1 - 0.0018 17.8 0.0 0.005 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAG11651.1 - 0.0055 16.1 0.0 0.087 12.1 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OAG11651.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 OAG11651.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 OAG11651.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 OAG11651.1 - 0.2 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aminotran_1_2 PF00155.21 OAG11652.1 - 3.3e-35 122.0 0.0 4.8e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II NAR PF16251.5 OAG11652.1 - 0.033 14.8 0.0 9 7.0 0.0 2.7 3 0 0 3 3 3 0 Nucleic acid-binding domain (NAR) Cys_Met_Meta_PP PF01053.20 OAG11652.1 - 0.056 12.0 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.9 OAG11653.1 - 1.5e-55 187.6 0.7 2.5e-55 186.9 0.7 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAG11653.1 - 2.8e-14 53.5 0.0 6.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 OAG11653.1 - 0.05 13.8 0.3 0.16 12.2 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 OAG11654.1 - 1.4e-73 248.0 0.0 6.1e-50 170.2 0.0 2.3 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 OAG11654.1 - 8.6e-10 39.2 0.0 1.8e-06 28.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG11654.1 - 1.2e-09 38.8 0.2 6.1e-09 36.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG11654.1 - 3.2e-06 27.7 0.2 7.2e-05 23.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG11654.1 - 4.1e-05 23.4 0.0 0.00024 21.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG11654.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Raftlin PF15250.6 OAG11654.1 - 0.00066 18.6 2.5 0.00085 18.2 0.1 1.9 2 0 0 2 2 2 1 Raftlin NNMT_PNMT_TEMT PF01234.17 OAG11654.1 - 0.018 14.2 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 OAG11654.1 - 0.17 11.8 1.3 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain ATHILA PF03078.15 OAG11654.1 - 2.1 7.1 3.2 3.2 6.4 0.1 2.0 2 0 0 2 2 2 0 ATHILA ORF-1 family DDRGK PF09756.9 OAG11654.1 - 4.3 6.9 9.5 0.4 10.3 1.5 2.8 3 0 0 3 3 3 0 DDRGK domain PEX11 PF05648.14 OAG11655.1 - 6.3e-71 238.4 0.8 7e-71 238.2 0.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.24 OAG11657.1 - 2.9e-26 92.3 23.6 3.7e-15 55.7 8.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG11657.1 - 1.8e-13 50.2 35.3 1.8e-13 50.2 35.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PEMT PF04191.13 OAG11657.1 - 0.26 11.7 0.1 0.26 11.7 0.1 3.1 5 0 0 5 5 5 0 Phospholipid methyltransferase DUF4538 PF15061.6 OAG11657.1 - 0.87 9.4 0.0 0.87 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Gram_pos_anchor PF00746.21 OAG11657.1 - 2.8 8.0 5.4 0.6 10.1 0.5 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Abhydrolase_6 PF12697.7 OAG11658.1 - 1.6e-15 58.3 0.0 1.9e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG11658.1 - 4.5e-06 26.1 0.1 2.6e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG11658.1 - 0.022 14.4 0.1 0.11 12.1 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Pribosyltran PF00156.27 OAG11658.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DLH PF01738.18 OAG11658.1 - 0.099 12.2 0.1 3.5 7.1 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Transcrip_reg PF01709.20 OAG11658.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Glyco_transf_4 PF13439.6 OAG11658.1 - 0.12 12.3 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Gallidermin PF02052.15 OAG11660.1 - 0.084 13.2 0.8 1.2 9.6 0.4 2.6 2 0 0 2 2 2 0 Gallidermin Mem_trans PF03547.18 OAG11661.1 - 2.7e-20 72.1 0.3 6.2e-20 70.9 0.3 1.5 1 1 0 1 1 1 1 Membrane transport protein DUF997 PF06196.12 OAG11661.1 - 3.3 7.8 10.8 0.34 11.0 1.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF997) Ras PF00071.22 OAG11662.1 - 6.7e-15 55.1 0.0 3.2e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG11662.1 - 0.0026 17.9 0.0 0.032 14.4 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG11662.1 - 0.0049 16.3 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 OAG11662.1 - 0.047 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SGL PF08450.12 OAG11663.1 - 3.9e-30 105.2 0.1 8.2e-30 104.2 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAG11663.1 - 4.4e-05 23.6 0.1 0.00015 21.9 0.0 2.0 2 0 0 2 2 2 1 Arylesterase NHL PF01436.21 OAG11663.1 - 8.5e-05 22.4 2.3 0.28 11.3 0.0 3.3 3 0 0 3 3 3 2 NHL repeat Str_synth PF03088.16 OAG11663.1 - 0.17 12.1 0.0 0.47 10.6 0.0 1.8 1 1 0 1 1 1 0 Strictosidine synthase PBP_like_2 PF12849.7 OAG11664.1 - 0.012 15.4 0.0 0.056 13.1 0.0 1.9 1 1 0 1 1 1 0 PBP superfamily domain HATPase_c PF02518.26 OAG11666.1 - 1.2e-23 83.8 0.0 2.6e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG11666.1 - 1.6e-20 73.4 0.1 1.9e-19 69.9 0.1 2.5 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG11666.1 - 1.9e-11 43.8 0.0 4.6e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 OAG11666.1 - 7.4e-06 26.2 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 2 PAS fold TadZ_N PF16968.5 OAG11666.1 - 0.014 15.1 0.3 0.077 12.7 0.0 2.3 2 1 0 2 2 2 0 Pilus assembly protein TadZ N-terminal PAS_8 PF13188.7 OAG11666.1 - 0.084 12.9 0.0 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 PAS domain MFS_1 PF07690.16 OAG11669.1 - 2.4e-33 115.5 34.7 2.4e-33 115.5 34.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cupin_2 PF07883.11 OAG11670.1 - 0.00026 20.6 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain F-box-like_2 PF13013.6 OAG11671.1 - 0.029 14.3 0.0 0.26 11.3 0.0 2.4 1 1 0 1 1 1 0 F-box-like domain CFEM PF05730.11 OAG11672.1 - 3.4e-13 49.5 8.1 5.8e-13 48.7 8.1 1.3 1 0 0 1 1 1 1 CFEM domain Beta-lactamase PF00144.24 OAG11675.1 - 0.0053 16.1 0.0 0.006 15.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase But2 PF09792.9 OAG11676.1 - 4.2e-13 49.9 5.5 4.8e-13 49.7 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain Chitin_bind_1 PF00187.19 OAG11676.1 - 0.00091 19.7 17.6 0.00091 19.7 17.6 2.4 2 1 0 2 2 2 1 Chitin recognition protein MFS_1 PF07690.16 OAG11677.1 - 2.4e-38 132.0 44.1 2.4e-38 132.0 44.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG11677.1 - 1.7e-08 33.8 21.3 1.8e-08 33.7 17.0 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter CPP1-like PF11833.8 OAG11677.1 - 3.6 7.2 5.3 45 3.6 0.1 2.9 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Glyco_hydro_92 PF07971.12 OAG11678.1 - 8.7e-136 453.5 1.1 1.1e-135 453.2 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAG11678.1 - 8.5e-49 166.6 3.4 1.2e-48 166.1 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain vATP-synt_AC39 PF01992.16 OAG11679.1 - 6.3e-105 351.4 0.0 7.1e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit UL16 PF17622.2 OAG11679.1 - 0.1 12.2 0.1 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 Viral unique long protein 16 BNR_2 PF13088.6 OAG11681.1 - 4.4e-16 59.0 1.5 4.7e-15 55.6 1.5 2.7 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OAG11681.1 - 6.9e-09 34.4 19.2 0.48 10.6 0.2 6.2 6 0 0 6 6 6 5 BNR/Asp-box repeat BNR_4 PF15892.5 OAG11681.1 - 0.00062 19.2 0.2 0.0075 15.7 0.0 2.4 1 1 1 2 2 2 1 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 OAG11681.1 - 0.034 13.0 3.8 12 4.6 0.1 3.4 2 1 2 4 4 4 0 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 OAG11681.1 - 0.044 13.0 1.4 3.7 6.7 0.0 3.6 2 1 1 4 4 4 0 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.16 OAG11681.1 - 0.33 11.0 4.3 2.8 7.9 0.0 3.8 3 1 1 5 5 5 0 Mo-co oxidoreductase dimerisation domain 5TM-5TMR_LYT PF07694.12 OAG11682.1 - 0.0021 17.6 0.2 0.0025 17.3 0.2 1.0 1 0 0 1 1 1 1 5TMR of 5TMR-LYT Fungal_trans_2 PF11951.8 OAG11683.1 - 0.00014 20.8 0.1 0.0008 18.3 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CTC1_2 PF15491.6 OAG11683.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 cNMP_binding PF00027.29 OAG11684.1 - 5.6e-43 144.9 0.0 1.6e-21 76.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OAG11684.1 - 8.6e-11 41.3 0.3 2.1e-10 40.1 0.3 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AMPK1_CBM PF16561.5 OAG11685.1 - 1.5e-25 89.3 1.4 3e-25 88.3 1.4 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 OAG11685.1 - 0.00015 22.0 0.5 0.00036 20.8 0.5 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 OAG11685.1 - 0.0035 17.9 1.6 0.0075 16.8 1.6 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Melibiase_2 PF16499.5 OAG11687.1 - 7.9e-61 205.7 7.5 1.6e-60 204.7 7.5 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OAG11687.1 - 2.8e-10 40.1 0.6 1.2e-09 38.1 0.1 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG11687.1 - 2.9e-07 29.8 0.0 5.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Melibiase DUF3584 PF12128.8 OAG11688.1 - 0.12 9.9 0.0 0.16 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Abhydrolase_2 PF02230.16 OAG11689.1 - 1.1e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase UnbV_ASPIC PF07593.12 OAG11689.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV Hydrolase_4 PF12146.8 OAG11689.1 - 0.18 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_61 PF03443.14 OAG11690.1 - 5e-65 219.3 1.0 5.9e-65 219.1 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Gag_p10 PF02337.17 OAG11690.1 - 0.11 12.4 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein PEPCK_N PF17297.2 OAG11692.1 - 0.15 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain Pribosyl_synth PF14572.6 OAG11693.1 - 1.1e-38 133.1 1.8 2.2e-33 115.9 0.7 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OAG11693.1 - 6.2e-35 119.6 0.0 2.1e-34 118.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 OAG11693.1 - 2.1e-14 53.4 0.4 1.4e-13 50.7 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG11693.1 - 0.00065 19.2 0.1 0.001 18.6 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ICL PF00463.21 OAG11694.1 - 5.9e-297 985.3 2.4 6.7e-297 985.1 2.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAG11694.1 - 1.5e-10 41.0 0.3 3.7e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF1365 PF07103.11 OAG11695.1 - 8.6e-54 182.7 0.0 1.3e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Glyco_hydro_1 PF00232.18 OAG11696.1 - 4.5e-148 493.4 0.0 5.2e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 An_peroxidase PF03098.15 OAG11697.1 - 9.9e-122 407.2 0.0 1.2e-121 406.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase RasGAP PF00616.19 OAG11700.1 - 2.4e-33 115.6 0.6 6.1e-23 81.6 0.0 3.3 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 OAG11700.1 - 7.1e-06 26.5 0.0 0.025 15.1 0.0 3.3 3 0 0 3 3 3 2 PH domain C2 PF00168.30 OAG11700.1 - 0.00075 19.7 0.0 0.0024 18.2 0.0 1.8 2 0 0 2 2 2 1 C2 domain Pro_isomerase PF00160.21 OAG11701.1 - 4.1e-48 163.6 0.3 7.1e-48 162.8 0.3 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 OAG11701.1 - 0.00023 20.9 10.9 0.097 12.5 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG11701.1 - 0.00046 20.1 11.0 0.011 15.8 0.5 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG11701.1 - 0.14 12.5 3.7 1.2 9.5 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG11701.1 - 0.27 11.6 7.2 0.9 9.9 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG11701.1 - 0.3 11.8 7.6 1.3 9.7 2.9 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG11701.1 - 0.43 10.8 2.0 2.2 8.5 0.5 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG11701.1 - 9.5 7.1 5.9 6.7 7.6 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat IFRD PF05004.13 OAG11702.1 - 2.8e-69 233.6 1.9 3.9e-69 233.1 1.9 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 OAG11702.1 - 0.00055 20.3 0.9 0.93 9.9 0.1 2.6 2 0 0 2 2 2 2 HEAT repeats GDE_C PF06202.14 OAG11702.1 - 0.064 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase zf-C2H2 PF00096.26 OAG11703.1 - 0.0027 18.1 3.9 0.0051 17.2 3.9 1.5 1 1 0 1 1 1 1 Zinc finger, C2H2 type Not3 PF04065.15 OAG11705.1 - 2.5e-87 292.1 33.3 2.5e-87 292.1 33.3 1.9 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OAG11705.1 - 2.8e-43 147.2 12.1 8e-43 145.7 12.1 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 OAG11705.1 - 0.0044 16.8 2.4 0.01 15.7 2.4 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) PulA_N1 PF17999.1 OAG11705.1 - 0.27 12.0 2.6 0.28 11.9 0.3 2.2 2 0 0 2 2 2 0 Pullulanase N1-terminal domain Serine_rich PF08824.10 OAG11705.1 - 0.86 9.6 8.9 0.81 9.7 1.0 2.9 1 1 1 2 2 2 0 Serine rich protein interaction domain Tyr_Deacylase PF02580.16 OAG11706.1 - 9.7e-51 172.1 0.1 1.3e-50 171.6 0.1 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF3689 PF12463.8 OAG11706.1 - 0.071 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) Feld-I_B PF09252.10 OAG11706.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Allergen Fel d I-B chain TMEM154 PF15102.6 OAG11711.1 - 0.014 15.3 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family MFS_1 PF07690.16 OAG11712.1 - 8.8e-34 117.0 32.3 1.8e-33 115.9 29.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG11712.1 - 4.7e-10 38.9 6.5 4.7e-10 38.9 6.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG11712.1 - 6.6e-08 31.4 6.1 1.2e-07 30.6 6.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG11712.1 - 0.58 8.4 8.9 0.54 8.5 0.0 3.5 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3638 PF12340.8 OAG11713.1 - 2.6e-83 278.8 0.6 4.5e-83 278.0 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OAG11713.1 - 4.8e-17 61.1 0.3 9.5e-17 60.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Death PF00531.22 OAG11713.1 - 2.1 8.6 6.1 15 5.8 0.1 4.5 4 0 0 4 4 4 0 Death domain Fungal_trans PF04082.18 OAG11715.1 - 3.9e-15 55.6 2.7 9e-15 54.4 2.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG11715.1 - 6.2e-09 35.8 8.9 0.00028 21.2 0.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG11715.1 - 0.015 16.1 9.5 1.5 9.9 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 OAG11715.1 - 0.046 14.3 0.1 0.13 12.9 0.1 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain GvpK PF05121.12 OAG11718.1 - 0.0048 16.9 0.1 0.0075 16.3 0.1 1.2 1 0 0 1 1 1 1 Gas vesicle protein K POR PF01558.18 OAG11719.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Cas_Csy4 PF09618.10 OAG11719.1 - 0.27 11.4 1.9 0.44 10.7 1.9 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Trehalase PF01204.18 OAG11720.1 - 1.2e-198 661.1 0.1 1.4e-198 660.9 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 OAG11720.1 - 7.3e-17 60.8 0.2 1.2e-16 60.1 0.2 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain OCRE PF17780.1 OAG11720.1 - 0.076 13.1 0.1 0.24 11.4 0.1 1.9 1 0 0 1 1 1 0 OCRE domain MBF1 PF08523.10 OAG11721.1 - 6.4e-27 93.8 1.9 6.4e-27 93.8 1.9 1.5 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OAG11721.1 - 3.3e-07 30.2 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix FTHFS PF01268.19 OAG11723.1 - 5.5e-256 850.1 0.1 8.5e-256 849.5 0.0 1.3 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 OAG11723.1 - 9.3e-66 220.1 2.6 9.3e-66 220.1 2.6 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OAG11723.1 - 9.3e-37 125.9 0.3 2e-36 124.8 0.3 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 OAG11723.1 - 0.01 14.8 1.5 0.01 14.8 0.2 1.5 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Helicase_C_4 PF13871.6 OAG11723.1 - 0.047 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue GTP_EFTU PF00009.27 OAG11723.1 - 0.063 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Dicty_CTDC PF00526.18 OAG11724.1 - 0.022 14.6 1.7 0.048 13.6 1.7 1.6 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat WD40 PF00400.32 OAG11725.1 - 1.2e-23 83.0 0.7 3.6e-06 27.6 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG11725.1 - 3.6e-11 43.2 0.1 0.0061 16.8 0.0 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OAG11725.1 - 0.00086 19.0 0.4 0.0092 15.6 0.4 2.4 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 OAG11725.1 - 0.0012 18.2 0.0 0.11 11.8 0.0 2.8 2 1 2 4 4 4 1 WD40-like domain eIF2A PF08662.11 OAG11725.1 - 0.0012 18.7 0.0 0.85 9.5 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OAG11725.1 - 0.014 14.5 0.2 0.18 10.8 0.0 2.3 2 1 1 3 3 3 0 Coatomer WD associated region Gmad1 PF10647.9 OAG11725.1 - 0.042 13.6 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.16 OAG11725.1 - 0.054 12.0 0.3 0.14 10.6 0.0 1.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain His_Phos_1 PF00300.22 OAG11726.1 - 9.9e-09 35.2 0.2 6.6e-08 32.5 0.0 2.3 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Peptidase_C101 PF16218.5 OAG11726.1 - 0.025 13.8 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C101 DNA_alkylation PF08713.11 OAG11726.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme Iso_dh PF00180.20 OAG11727.1 - 2.1e-72 244.2 0.0 2.5e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WD40 PF00400.32 OAG11730.1 - 7.2e-08 33.0 13.0 5.5e-05 23.9 0.1 5.2 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG11730.1 - 0.00012 22.3 0.1 2.9 8.3 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAG11730.1 - 0.00028 20.7 5.1 1.5 8.8 0.3 4.3 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OAG11730.1 - 0.0042 16.1 0.2 0.31 10.0 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 OAG11730.1 - 0.015 13.8 0.2 0.14 10.6 0.1 2.5 2 1 1 3 3 3 0 Cytochrome D1 heme domain NACHT PF05729.12 OAG11731.1 - 1.6e-07 31.4 0.0 3.5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG11731.1 - 5.7e-07 30.1 0.4 1.5e-05 25.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 OAG11731.1 - 3.2e-06 26.7 0.1 7.4e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins WD40 PF00400.32 OAG11731.1 - 1.7e-05 25.5 0.2 4.3e-05 24.2 0.2 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat AAA PF00004.29 OAG11731.1 - 0.00025 21.5 0.0 0.00087 19.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG11731.1 - 0.00068 19.9 0.0 0.0033 17.7 0.0 2.3 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 OAG11731.1 - 0.006 15.8 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 OAG11731.1 - 0.0066 17.0 0.0 0.03 14.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 OAG11731.1 - 0.046 13.6 0.1 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 OAG11731.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 OAG11731.1 - 0.07 12.8 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 OAG11731.1 - 0.079 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 OAG11731.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG11731.1 - 0.11 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 OAG11731.1 - 0.12 11.6 0.1 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.22 OAG11731.1 - 0.17 12.3 0.1 0.98 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 OAG11731.1 - 0.19 11.7 0.8 4.8 7.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF3606 PF12244.8 OAG11731.1 - 0.23 11.4 1.5 0.96 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) GCN5L1 PF06320.13 OAG11734.1 - 0.14 12.3 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Peptidase_C15 PF01470.17 OAG11735.1 - 0.00093 19.4 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Pyroglutamyl peptidase His_Phos_1 PF00300.22 OAG11736.1 - 1.2e-26 93.6 0.0 2.3e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OAG11736.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) P5-ATPase PF12409.8 OAG11736.1 - 0.15 12.1 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF1168 PF06658.12 OAG11737.1 - 4.3e-40 136.7 17.6 6.5e-40 136.1 17.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF966 PF06136.13 OAG11737.1 - 0.024 14.4 5.6 0.026 14.3 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Lyase_catalyt PF09093.11 OAG11737.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic XRN_M PF17846.1 OAG11737.1 - 0.57 9.1 5.6 0.7 8.8 5.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain PPL5 PF18168.1 OAG11737.1 - 0.6 9.4 4.9 0.76 9.0 4.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Neur_chan_memb PF02932.16 OAG11737.1 - 1.4 8.9 3.0 1.5 8.9 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 OAG11737.1 - 2.2 8.3 10.1 3.6 7.6 10.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rrn6 PF10214.9 OAG11737.1 - 2.3 6.6 8.5 2.7 6.4 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3340 PF11818.8 OAG11737.1 - 3.6 7.7 17.6 7.9 6.6 17.6 1.5 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) RR_TM4-6 PF06459.12 OAG11737.1 - 3.9 7.2 14.0 5.1 6.8 14.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 OAG11737.1 - 5.7 5.6 7.4 6.9 5.3 7.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NARP1 PF12569.8 OAG11737.1 - 6.4 5.6 17.8 8.2 5.2 17.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pro-rich PF15240.6 OAG11737.1 - 8.1 6.7 14.4 0.65 10.3 9.2 1.7 2 0 0 2 2 2 0 Proline-rich HET PF06985.11 OAG11739.1 - 6.2e-29 101.2 0.0 1.1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Condensation PF00668.20 OAG11740.1 - 0 1294.7 0.0 6.2e-52 176.8 0.0 9.4 9 1 0 9 9 9 9 Condensation domain AMP-binding PF00501.28 OAG11740.1 - 0 1037.4 0.0 2.7e-78 263.5 0.0 4.4 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.25 OAG11740.1 - 3.1e-77 254.9 9.0 1.4e-12 47.8 0.2 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG11740.1 - 2.2e-06 28.5 0.0 0.089 13.8 0.0 4.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 OAG11740.1 - 0.0012 17.6 0.0 3.7 6.1 0.0 4.3 5 0 0 5 5 5 2 Transferase family AMP-binding PF00501.28 OAG11741.1 - 4.3e-69 233.1 0.0 5.5e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAG11741.1 - 0.069 11.8 0.0 2.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Condensation domain ABC_tran PF00005.27 OAG11742.1 - 1.9e-44 151.5 0.0 2.2e-22 80.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG11742.1 - 5.6e-27 95.1 35.1 1.6e-23 83.8 15.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG11742.1 - 6.5e-11 42.1 6.1 0.00028 20.4 0.2 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG11742.1 - 4.8e-08 33.6 0.8 0.0081 16.5 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG11742.1 - 6e-08 32.9 0.7 0.054 13.3 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG11742.1 - 4.4e-07 29.5 0.7 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG11742.1 - 2.2e-06 27.7 0.1 0.0074 16.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG11742.1 - 1.2e-05 25.3 0.5 0.16 12.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG11742.1 - 1.8e-05 25.0 3.4 0.043 14.1 0.2 3.4 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OAG11742.1 - 4.6e-05 23.0 0.4 0.031 13.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 OAG11742.1 - 0.00018 22.1 0.1 0.17 12.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG11742.1 - 0.00023 21.6 0.1 0.022 15.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAG11742.1 - 0.00095 18.8 0.3 1.6 8.3 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 OAG11742.1 - 0.0039 17.3 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OAG11742.1 - 0.004 17.2 1.6 0.38 10.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 OAG11742.1 - 0.0044 16.1 0.9 0.057 12.5 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 OAG11742.1 - 0.005 17.2 0.0 2 8.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Viral_helicase1 PF01443.18 OAG11742.1 - 0.0051 16.6 0.5 0.33 10.7 0.0 2.9 4 0 0 4 4 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 OAG11742.1 - 0.0052 16.0 0.1 1.9 7.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 OAG11742.1 - 0.0059 15.8 0.3 1.1 8.4 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain AAA_PrkA PF08298.11 OAG11742.1 - 0.0091 14.9 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 1 PrkA AAA domain ABC_ATPase PF09818.9 OAG11742.1 - 0.014 14.3 3.5 0.11 11.2 0.3 3.2 4 0 0 4 4 4 0 Predicted ATPase of the ABC class AAA_11 PF13086.6 OAG11742.1 - 0.015 15.1 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OAG11742.1 - 0.019 14.7 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 OAG11742.1 - 0.02 14.3 0.3 0.5 9.7 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Adeno_IVa2 PF02456.15 OAG11742.1 - 0.026 13.3 0.2 0.16 10.7 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_24 PF13479.6 OAG11742.1 - 0.03 14.1 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAG11742.1 - 0.033 14.3 4.0 0.05 13.7 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase_2 PF01637.18 OAG11742.1 - 0.034 14.1 0.2 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 OAG11742.1 - 0.035 14.1 1.1 10 6.1 0.2 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 OAG11742.1 - 0.035 14.0 1.1 4 7.3 0.3 2.6 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 OAG11742.1 - 0.039 13.7 2.4 21 4.8 0.1 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein NACHT PF05729.12 OAG11742.1 - 0.041 13.8 1.8 10 6.0 0.2 3.1 3 0 0 3 3 2 0 NACHT domain TsaE PF02367.17 OAG11742.1 - 0.044 13.8 1.2 1.4 9.0 0.1 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OAG11742.1 - 0.048 13.4 0.8 1.8 8.2 0.2 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 OAG11742.1 - 0.05 13.4 1.3 0.9 9.3 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 OAG11742.1 - 0.067 13.1 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 OAG11742.1 - 0.075 12.3 1.2 0.67 9.2 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 OAG11742.1 - 0.075 13.2 3.1 6.9 6.9 0.1 3.7 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 OAG11742.1 - 0.095 12.7 0.5 1.4 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 OAG11742.1 - 0.1 13.2 0.0 9.5 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OAG11742.1 - 0.12 12.0 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 OAG11742.1 - 0.16 11.3 0.4 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 OAG11742.1 - 0.19 11.0 1.4 5 6.3 0.2 2.2 2 0 0 2 2 2 0 Septin SbcCD_C PF13558.6 OAG11742.1 - 0.2 11.9 0.3 6 7.2 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 OAG11742.1 - 0.24 11.1 1.0 21 4.8 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase cobW PF02492.19 OAG11742.1 - 0.25 10.9 3.3 1.1 8.8 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 OAG11742.1 - 0.28 10.9 2.0 10 5.8 0.3 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF1115 PF06544.12 OAG11744.1 - 1.8e-10 41.1 0.0 2.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DIM1 PF02966.16 OAG11745.1 - 1.2e-69 232.2 0.5 1.4e-69 232.0 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OAG11745.1 - 0.048 13.6 0.1 0.062 13.3 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin PIG-H PF10181.9 OAG11746.1 - 6.4e-25 86.8 0.2 9.7e-25 86.2 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF1472 PF07339.12 OAG11746.1 - 0.19 12.3 2.0 17 6.0 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1472) ubiquitin PF00240.23 OAG11747.1 - 0.0062 16.3 0.0 0.0086 15.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 OAG11747.1 - 0.018 15.7 0.0 0.032 14.9 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PseudoU_synth_1 PF01416.20 OAG11748.1 - 7.6e-31 106.8 0.0 1.1e-29 103.0 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase Acyl_transf_3 PF01757.22 OAG11749.1 - 3.8e-23 82.1 28.4 5.1e-23 81.7 28.1 1.3 1 1 0 1 1 1 1 Acyltransferase family VIT PF08487.10 OAG11750.1 - 1.9e-35 121.4 1.2 3.7e-35 120.5 1.2 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 OAG11750.1 - 2.6e-27 95.6 0.0 6.5e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 OAG11750.1 - 6.8e-17 61.1 0.4 2.1e-16 59.5 0.1 2.1 3 0 0 3 3 3 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OAG11750.1 - 2.3e-10 41.0 0.0 8.2e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG11750.1 - 1.6e-08 35.2 0.0 4.3e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain BNR PF02012.20 OAG11751.1 - 0.076 13.1 0.7 0.56 10.4 0.1 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Alpha-amylase_C PF02806.18 OAG11751.1 - 0.33 11.4 1.5 47 4.5 0.0 3.0 1 1 2 3 3 3 0 Alpha amylase, C-terminal all-beta domain AidB_N PF18158.1 OAG11752.1 - 2.3e-14 53.6 0.1 6e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG11752.1 - 3.3e-13 50.1 0.4 4.1e-12 46.6 0.4 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG11752.1 - 1e-09 38.4 0.0 6e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Pyridox_ox_2 PF12900.7 OAG11753.1 - 5.8e-38 130.1 0.0 9.2e-38 129.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aa_trans PF01490.18 OAG11754.1 - 4.7e-30 104.6 36.0 6e-30 104.3 36.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3341 PF11821.8 OAG11754.1 - 0.78 9.4 8.3 0.099 12.3 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) ATPase_2 PF01637.18 OAG11756.1 - 3.1e-12 46.9 0.0 4.1e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OAG11756.1 - 2.3e-07 31.3 1.8 1.7e-06 28.5 1.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG11756.1 - 9.7e-07 29.1 0.6 0.00087 19.6 0.0 2.8 2 1 1 3 3 3 2 AAA domain ResIII PF04851.15 OAG11756.1 - 0.0016 18.5 0.0 0.017 15.1 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RNA12 PF10443.9 OAG11756.1 - 0.019 13.7 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein AAA_14 PF13173.6 OAG11756.1 - 0.068 13.2 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.8 OAG11759.1 - 0.003 16.9 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PLDc PF00614.22 OAG11760.1 - 1.6e-15 56.5 0.4 2e-06 27.7 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OAG11760.1 - 3.2e-13 49.7 0.0 2.2e-07 30.8 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 OAG11760.1 - 1.8e-09 37.5 0.0 1.3e-08 34.8 0.0 2.5 1 1 0 1 1 1 1 PX domain Alpha-amylase PF00128.24 OAG11761.1 - 3.6e-57 194.4 0.0 5.4e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 OAG11761.1 - 4.9e-19 68.4 0.0 1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.16 OAG11761.1 - 1.5e-05 23.4 0.6 0.0028 16.0 0.0 3.1 2 1 1 3 3 3 2 Glycosyl hydrolase family 70 Aldedh PF00171.22 OAG11762.1 - 1e-116 390.3 4.2 1.2e-116 390.0 4.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG11762.1 - 0.0041 16.2 0.4 0.0096 15.0 0.4 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) PIP49_C PF12260.8 OAG11762.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 HMG_box PF00505.19 OAG11763.1 - 1.8e-09 37.8 1.2 4.9e-09 36.5 0.7 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 OAG11763.1 - 1.1e-07 32.2 0.0 2.9e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAG11763.1 - 1.8e-06 28.0 0.0 3.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 OAG11763.1 - 0.005 17.4 0.4 0.013 16.1 0.4 1.8 1 0 0 1 1 1 1 HMG-box domain Fungal_trans PF04082.18 OAG11763.1 - 0.032 13.2 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain FAM60A PF15396.6 OAG11763.1 - 0.068 13.2 1.2 0.13 12.3 1.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Sugar_tr PF00083.24 OAG11765.1 - 1.3e-90 304.4 33.2 1.6e-90 304.1 33.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG11765.1 - 1.1e-16 60.8 56.1 5.1e-14 52.0 45.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF412 PF04217.13 OAG11765.1 - 0.12 12.3 3.4 0.64 9.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF412 GTP_EFTU PF00009.27 OAG11766.1 - 2.9e-50 170.5 0.0 4.7e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OAG11766.1 - 1.6e-43 147.2 2.5 2.8e-43 146.4 2.5 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OAG11766.1 - 2.4e-19 69.1 0.0 4.6e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG11766.1 - 2e-07 31.3 0.1 5.1e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG11766.1 - 3.7e-05 23.8 0.0 8.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAG11766.1 - 0.00033 20.3 0.0 0.00078 19.1 0.0 1.6 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 OAG11766.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 OAG11766.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 OAG11766.1 - 0.03 13.8 0.0 0.075 12.5 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Snurportin1 PF11538.8 OAG11766.1 - 0.23 11.7 2.9 0.52 10.5 2.9 1.6 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.18 OAG11767.1 - 5.9e-34 117.5 0.3 7.3e-34 117.2 0.3 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 OAG11767.1 - 0.00026 21.0 0.7 0.0012 18.9 0.7 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF4760 PF15956.5 OAG11767.1 - 0.056 13.6 0.4 0.11 12.6 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4760) Glyco_trans_2_3 PF13632.6 OAG11768.1 - 1.5e-47 162.1 0.2 7.5e-47 159.8 0.2 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG11768.1 - 3.7e-08 33.4 0.1 6.1e-07 29.4 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG11768.1 - 0.026 14.0 0.2 0.096 12.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 RNA_pol_Rpb1_1 PF04997.12 OAG11770.1 - 2.4e-82 276.8 0.2 4.4e-82 275.9 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OAG11770.1 - 5.7e-78 262.0 0.1 1.1e-77 261.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAG11770.1 - 1.1e-69 233.9 0.0 3e-69 232.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAG11770.1 - 1.2e-32 113.1 0.0 2.8e-32 111.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OAG11770.1 - 9.8e-26 89.8 0.0 4.6e-25 87.7 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 PCB_OB PF17092.5 OAG11770.1 - 0.065 14.0 0.2 2.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain FHA PF00498.26 OAG11771.1 - 7.9e-14 51.8 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG11771.1 - 0.0017 18.6 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Amidohydro_1 PF01979.20 OAG11772.1 - 8.5e-18 64.8 2.2 3.5e-17 62.7 2.2 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG11772.1 - 1.4e-11 44.6 4.9 8.3e-08 32.1 0.0 2.7 1 1 2 3 3 3 2 Amidohydrolase family MFS_1 PF07690.16 OAG11773.1 - 1.4e-24 86.7 43.9 6.8e-20 71.3 11.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG11773.1 - 1.1e-11 44.3 0.1 1.1e-11 44.3 0.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG11773.1 - 0.003 16.1 0.3 0.0043 15.5 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4051 PF13260.6 OAG11773.1 - 0.1 12.4 3.5 0.22 11.3 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Sugar_tr PF00083.24 OAG11774.1 - 1.4e-89 301.1 16.9 5.1e-89 299.2 16.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG11774.1 - 1.1e-27 96.9 29.6 3.7e-18 65.6 10.1 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 OAG11775.1 - 4.5e-18 65.3 54.6 2.7e-14 52.9 33.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-CCCH PF00642.24 OAG11777.1 - 2.7e-07 30.3 16.9 1.3e-06 28.1 3.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG11777.1 - 6e-06 26.1 5.2 6e-06 26.1 5.2 2.6 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 OAG11777.1 - 0.00012 22.7 16.1 0.02 15.6 2.5 3.5 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 OAG11777.1 - 0.083 13.4 16.8 0.56 10.8 3.3 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MFS_1 PF07690.16 OAG11781.1 - 3.1e-44 151.3 56.7 8e-44 150.0 56.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG11781.1 - 7.8e-18 64.2 21.7 9.8e-18 63.9 21.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Beta-APP PF03494.13 OAG11781.1 - 0.0079 16.0 1.6 0.028 14.2 1.6 2.0 1 0 0 1 1 1 1 Beta-amyloid peptide (beta-APP) P5-ATPase PF12409.8 OAG11781.1 - 0.059 13.5 0.8 0.15 12.2 0.8 1.6 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF3602 PF12223.8 OAG11783.1 - 6.7e-21 74.7 8.3 1.7e-18 66.9 0.3 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Actin PF00022.19 OAG11785.1 - 8.3e-126 419.9 0.0 3.8e-125 417.7 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAG11785.1 - 0.00081 18.3 0.0 0.026 13.4 0.0 2.7 1 1 0 1 1 1 1 MreB/Mbl protein Exo_endo_phos PF03372.23 OAG11786.1 - 2.4e-10 40.4 0.0 4.5e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 OAG11787.1 - 2.2e-52 178.3 0.0 3.2e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG11788.1 - 2.9e-29 102.1 30.6 2.9e-29 102.1 30.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG11788.1 - 9.1e-11 41.3 9.8 9.1e-11 41.3 9.8 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter Pkinase PF00069.25 OAG11789.1 - 1.2e-27 97.0 0.0 1.8e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11789.1 - 1.4e-14 54.0 0.0 2.1e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LisH_2 PF16045.5 OAG11789.1 - 0.15 11.1 0.4 0.3 10.2 0.4 1.5 1 0 0 1 1 1 0 LisH Phage_int_SAM_1 PF02899.17 OAG11789.1 - 0.4 11.0 3.5 14 6.0 0.1 3.4 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Lactonase PF10282.9 OAG11790.1 - 1.7e-05 24.3 2.4 0.22 10.7 0.0 3.0 2 1 0 3 3 3 3 Lactonase, 7-bladed beta-propeller HAD_2 PF13419.6 OAG11791.1 - 3.5e-18 66.3 0.0 5.7e-18 65.6 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG11791.1 - 1.2e-09 38.8 0.2 1.1e-08 35.6 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG11791.1 - 0.00017 21.6 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2183 PF09949.9 OAG11791.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Glyco_hydro_16 PF00722.21 OAG11792.1 - 5.5e-15 55.3 0.1 7.6e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 OAG11793.1 - 4.7e-16 58.9 0.0 1.6e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11793.1 - 8.2e-12 45.0 0.0 1.7e-11 43.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase THRAP3_BCLAF1 PF15440.6 OAG11793.1 - 0.12 11.3 6.7 0.16 10.9 6.7 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Pkinase_fungal PF17667.1 OAG11793.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PsaN PF05479.11 OAG11794.1 - 0.067 13.4 2.9 0.66 10.2 1.0 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) TRP PF06011.12 OAG11796.1 - 7.6e-167 555.4 28.0 8.9e-167 555.1 28.0 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG11796.1 - 3.8e-39 134.2 0.1 6.3e-39 133.5 0.1 1.4 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.6 OAG11796.1 - 1.3 9.2 5.2 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator ADH_N PF08240.12 OAG11797.1 - 3.5e-25 88.0 1.9 9.4e-25 86.6 1.9 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG11797.1 - 7.8e-14 51.8 0.1 1.3e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG11797.1 - 2.2e-05 23.8 0.7 3.8e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG11797.1 - 0.00026 20.4 0.1 0.00041 19.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PRA-CH PF01502.18 OAG11797.1 - 0.047 13.5 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase AA_permease_2 PF13520.6 OAG11800.1 - 1.2e-51 175.9 43.1 1.5e-51 175.5 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG11800.1 - 5.1e-24 84.7 35.6 7.2e-24 84.2 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.29 OAG11802.1 - 2.9e-45 154.2 0.0 6.2e-45 153.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG11802.1 - 1.2e-24 86.8 0.0 3.9e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG11802.1 - 1.5e-18 66.8 0.2 3.6e-18 65.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 OAG11802.1 - 8.2e-06 25.2 0.0 8.2e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OAG11802.1 - 0.00032 20.7 0.6 0.00075 19.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cwf_Cwc_15 PF04889.12 OAG11802.1 - 0.5 10.1 19.3 0.76 9.5 19.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Prenylcys_lyase PF07156.14 OAG11803.1 - 4.8e-11 42.4 0.0 5.8e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Epimerase PF01370.21 OAG11804.1 - 1e-14 54.6 0.0 1.7e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG11804.1 - 8.3e-09 35.6 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG11804.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OAG11804.1 - 6.4e-05 22.1 0.0 0.0003 19.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG11804.1 - 9.5e-05 21.7 0.3 0.00089 18.5 0.1 2.2 1 1 1 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG11804.1 - 0.00011 21.8 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 OAG11804.1 - 0.0043 17.3 0.0 0.0079 16.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG11804.1 - 0.017 15.6 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAG11804.1 - 0.078 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 OAG11805.1 - 6.5e-68 228.9 0.0 8e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11805.1 - 3.6e-32 111.7 0.0 5.1e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG11805.1 - 0.0043 16.1 0.0 0.025 13.5 0.0 2.2 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAG11805.1 - 0.041 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG11805.1 - 0.049 13.0 0.1 0.1 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.23 OAG11806.1 - 1.1e-09 38.2 0.3 1.6e-09 37.7 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 OAG11806.1 - 5.4e-07 28.9 1.0 9.7e-07 28.1 1.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TAXi_N PF14543.6 OAG11806.1 - 0.0012 19.2 0.3 0.0024 18.1 0.3 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal VSP PF03302.13 OAG11806.1 - 0.0051 15.7 0.1 0.009 14.9 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein EphA2_TM PF14575.6 OAG11806.1 - 0.052 14.4 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_HK97_TLTM PF06120.11 OAG11806.1 - 0.079 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Podoplanin PF05808.11 OAG11806.1 - 0.095 12.8 0.8 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Podoplanin LapA_dom PF06305.11 OAG11806.1 - 0.097 12.5 0.4 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MtrF PF09472.10 OAG11806.1 - 0.68 9.4 2.4 1.2 8.6 2.4 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Zn_clus PF00172.18 OAG11808.1 - 0.058 13.5 4.6 0.53 10.4 0.8 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectate_lyase PF03211.13 OAG11809.1 - 2.3e-54 184.1 8.3 3.9e-34 118.0 5.1 2.0 1 1 1 2 2 2 2 Pectate lyase OTU PF02338.19 OAG11812.1 - 3.2e-20 72.9 2.0 5.8e-19 68.8 0.0 2.9 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAG11812.1 - 3e-05 23.6 0.7 0.031 13.7 0.0 3.0 2 1 1 3 3 3 2 Peptidase C65 Otubain PepSY_2 PF13670.6 OAG11812.1 - 0.012 15.6 0.6 0.041 13.9 0.6 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain TPMT PF05724.11 OAG11813.1 - 5.8e-31 107.8 0.0 8.2e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 OAG11813.1 - 6.7e-09 35.8 0.0 9.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG11813.1 - 1.4e-06 29.0 0.0 3.5e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG11813.1 - 2.1e-05 25.1 0.0 0.00011 22.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG11813.1 - 0.00011 22.0 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG11813.1 - 0.00015 22.4 0.0 0.0026 18.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 OAG11814.1 - 1.5e-37 129.4 52.0 8e-37 127.0 23.4 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG11814.1 - 3.8e-08 32.6 16.9 3.8e-08 32.6 16.9 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter AA_permease_2 PF13520.6 OAG11815.1 - 0.00012 21.0 0.1 0.00012 21.0 0.1 1.7 2 0 0 2 2 2 1 Amino acid permease YlaH PF14036.6 OAG11815.1 - 0.064 13.6 1.5 0.064 13.6 1.5 1.9 2 0 0 2 2 2 0 YlaH-like protein DUF5489 PF17592.2 OAG11815.1 - 0.93 10.1 5.3 0.19 12.3 1.6 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5489) MFS_1 PF07690.16 OAG11816.1 - 1.3e-38 132.9 37.5 1.3e-38 132.9 37.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane PF01061.24 OAG11818.1 - 2.4e-25 89.2 26.9 3.9e-25 88.5 26.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAG11818.1 - 1.9e-23 83.5 0.1 2.9e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAG11818.1 - 4.2e-06 26.8 0.1 0.027 14.3 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG11818.1 - 3.2e-05 23.9 0.1 9.5e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 OAG11818.1 - 0.00024 20.7 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG11818.1 - 0.0013 19.2 0.1 0.0024 18.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG11818.1 - 0.0033 17.7 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 OAG11818.1 - 0.0033 16.9 0.0 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG11818.1 - 0.0086 15.8 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 OAG11818.1 - 0.012 15.4 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAG11818.1 - 0.014 14.5 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 OAG11818.1 - 0.017 15.7 0.0 0.032 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAG11818.1 - 0.026 15.0 0.1 0.16 12.4 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OAG11818.1 - 0.034 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_13 PF13166.6 OAG11818.1 - 0.039 12.6 0.4 0.52 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAG11818.1 - 0.042 14.1 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAG11818.1 - 0.067 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 OAG11818.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 OAG11818.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAG11818.1 - 0.098 12.7 0.3 0.22 11.6 0.3 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG11818.1 - 0.099 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG11818.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 OAG11818.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 OAG11818.1 - 0.21 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea 2OG-FeII_Oxy_2 PF13532.6 OAG11819.1 - 2.1e-31 109.7 0.0 8.6e-31 107.6 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NUC130_3NT PF08158.12 OAG11819.1 - 0.13 12.6 0.0 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 NUC130/3NT domain IQ PF00612.27 OAG11819.1 - 0.3 11.0 1.0 0.57 10.1 1.0 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Calcipressin PF04847.12 OAG11819.1 - 0.48 10.1 2.8 0.75 9.5 2.2 1.5 2 0 0 2 2 2 0 Calcipressin Pkinase PF00069.25 OAG11820.1 - 3.6e-70 236.3 0.0 4.7e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11820.1 - 2e-31 109.2 0.0 3.3e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_18 PF00704.28 OAG11820.1 - 4.7e-14 52.8 0.0 4e-13 49.8 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 18 UBA PF00627.31 OAG11820.1 - 2.6e-05 24.0 0.2 6.3e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Kinase-like PF14531.6 OAG11820.1 - 0.0015 18.0 0.1 0.0048 16.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG11820.1 - 0.0016 17.5 0.2 0.035 13.0 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAG11820.1 - 0.0061 16.5 0.3 0.02 14.8 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family RuvA_C PF07499.13 OAG11820.1 - 0.025 15.0 0.1 1.5 9.3 0.1 2.7 1 1 1 2 2 2 0 RuvA, C-terminal domain Seadorna_VP7 PF07387.11 OAG11820.1 - 0.038 13.0 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OAG11820.1 - 0.054 12.8 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arrestin_C PF02752.22 OAG11821.1 - 1.7e-12 48.0 0.8 5.9e-11 43.0 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAG11821.1 - 1.5e-11 44.5 0.0 1.2e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.32 OAG11822.1 - 6.6e-13 48.9 10.9 0.0001 23.0 0.1 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG11822.1 - 6.5e-10 39.2 0.1 0.0058 16.9 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAG11822.1 - 0.00011 20.8 0.0 0.014 14.0 0.0 1.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 OAG11822.1 - 0.0019 18.1 0.2 0.041 13.8 0.1 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A YpsA PF06908.11 OAG11822.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.6 2 0 0 2 2 2 0 YspA SLOG family Lgl_C PF08596.10 OAG11822.1 - 0.025 13.3 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Utp8 PF10395.9 OAG11822.1 - 0.089 11.3 0.0 0.18 10.3 0.0 1.4 1 0 0 1 1 1 0 Utp8 family CpcD PF01383.21 OAG11822.1 - 0.16 12.3 0.1 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain EF_assoc_2 PF08356.12 OAG11823.1 - 1.9e-35 120.7 0.0 4.1e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 OAG11823.1 - 7e-29 99.3 0.2 1.3e-28 98.4 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 OAG11823.1 - 1.9e-25 89.3 0.0 4.3e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG11823.1 - 2.3e-13 50.4 0.0 2.7e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAG11823.1 - 2e-08 34.3 0.0 8.2e-06 25.9 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_6 PF13405.6 OAG11823.1 - 6.2e-07 28.8 2.8 0.013 15.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain RsgA_GTPase PF03193.16 OAG11823.1 - 1.1e-05 25.4 0.0 0.48 10.3 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase EF-hand_1 PF00036.32 OAG11823.1 - 1.4e-05 24.3 2.8 0.024 14.2 0.7 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 OAG11823.1 - 4.8e-05 23.8 0.1 0.1 12.9 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain EF-hand_7 PF13499.6 OAG11823.1 - 0.0002 21.7 0.4 0.21 12.0 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.6 OAG11823.1 - 0.00049 20.4 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAG11823.1 - 0.00084 19.7 0.1 0.5 10.8 0.0 2.7 3 0 0 3 3 2 1 RNA helicase AAA_29 PF13555.6 OAG11823.1 - 0.0017 18.0 0.1 0.91 9.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 OAG11823.1 - 0.0023 18.0 0.6 1.7 8.7 0.1 2.9 2 1 1 3 3 3 1 Dynamin family Septin PF00735.18 OAG11823.1 - 0.0026 17.1 0.0 0.76 9.0 0.0 2.3 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 OAG11823.1 - 0.0041 16.8 0.1 0.71 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG11823.1 - 0.0067 16.9 0.1 1.9 9.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter EF-hand_10 PF14788.6 OAG11823.1 - 0.013 15.4 1.2 0.46 10.4 0.1 2.4 2 0 0 2 2 2 0 EF hand NACHT PF05729.12 OAG11823.1 - 0.015 15.2 0.0 3.3 7.6 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 OAG11823.1 - 0.017 14.4 0.1 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 AIG1 family AAA_7 PF12775.7 OAG11823.1 - 0.018 14.5 0.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region EF-hand_8 PF13833.6 OAG11823.1 - 0.033 14.0 3.2 0.15 11.9 0.8 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 OAG11823.1 - 0.039 13.5 5.4 0.29 10.7 2.4 2.6 2 0 0 2 2 2 0 EF hand AAA_33 PF13671.6 OAG11823.1 - 0.095 12.9 0.0 6.1 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 OAG11823.1 - 0.097 12.4 1.0 23 4.7 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 OAG11823.1 - 0.2 12.2 1.6 1.6 9.3 0.1 3.0 4 1 0 4 4 2 0 AAA domain DUF87 PF01935.17 OAG11823.1 - 0.21 11.7 0.1 3 7.9 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Zds_C PF08632.10 OAG11824.1 - 6.7e-29 99.4 1.2 1.4e-28 98.3 1.2 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ribosomal_60s PF00428.19 OAG11824.1 - 0.77 10.4 0.0 0.77 10.4 0.0 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Fe-ADH PF00465.19 OAG11826.1 - 2.5e-103 345.7 0.0 3.2e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG11826.1 - 5.1e-14 52.6 0.1 7.8e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Bse634I PF07832.11 OAG11826.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease FMN_red PF03358.15 OAG11828.1 - 4.4e-28 98.0 0.2 8.5e-28 97.0 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OAG11828.1 - 0.018 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold COesterase PF00135.28 OAG11829.1 - 4.2e-53 181.0 0.0 5.6e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG11829.1 - 0.00036 20.5 0.0 0.0044 16.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold KR PF08659.10 OAG11830.1 - 6.5e-58 195.6 0.1 1.9e-57 194.1 0.1 1.8 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 OAG11830.1 - 4.1e-56 190.4 0.0 6.6e-28 98.0 0.0 2.8 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG11830.1 - 9.6e-55 186.3 0.1 1.6e-54 185.6 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OAG11830.1 - 1.8e-48 165.3 0.0 2.8e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 OAG11830.1 - 9e-37 125.7 0.0 3.3e-36 123.9 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OAG11830.1 - 1.9e-16 60.5 0.0 6.7e-16 58.7 0.0 2.0 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OAG11830.1 - 2.2e-10 40.3 0.1 5.9e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 OAG11830.1 - 4.6e-09 36.3 0.7 2e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 OAG11830.1 - 1.5e-08 34.5 0.0 7.1e-06 25.7 0.1 2.6 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 OAG11830.1 - 1.1e-07 32.1 0.3 3e-07 30.7 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 OAG11830.1 - 3.8e-06 28.0 0.1 2.9e-05 25.1 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG11830.1 - 3.7e-05 23.6 0.1 8.4e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 OAG11830.1 - 0.00025 20.5 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 OAG11830.1 - 0.0057 16.4 0.3 0.059 13.1 0.1 2.6 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Polysacc_synt_2 PF02719.15 OAG11830.1 - 0.0059 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG11830.1 - 5.8 6.4 5.8 19 4.7 0.2 2.9 3 0 0 3 3 3 0 NmrA-like family FSH1 PF03959.13 OAG11831.1 - 2.2e-26 92.8 0.0 8.6e-26 90.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ABC_membrane PF00664.23 OAG11832.1 - 2.2e-68 230.9 39.0 6.4e-42 144.1 14.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG11832.1 - 2.3e-63 212.7 0.0 2.5e-31 109.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG11832.1 - 3.2e-19 69.2 0.0 3.3e-06 26.7 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OAG11832.1 - 7.6e-09 35.7 0.0 0.002 17.9 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG11832.1 - 3.7e-08 33.4 0.2 0.00087 19.2 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 OAG11832.1 - 1.2e-07 32.0 0.7 0.038 14.3 0.1 3.6 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 OAG11832.1 - 1.8e-07 30.8 0.2 0.00067 19.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG11832.1 - 2.8e-07 31.1 0.5 0.044 14.2 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAG11832.1 - 2.6e-06 28.1 0.4 0.067 13.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 OAG11832.1 - 3.3e-06 27.1 0.0 0.2 11.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OAG11832.1 - 5.6e-05 23.6 0.2 2.1 8.8 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OAG11832.1 - 5.7e-05 22.9 0.1 0.91 9.2 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 OAG11832.1 - 7.8e-05 22.7 0.0 0.48 10.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OAG11832.1 - 0.00022 21.2 0.0 0.073 13.0 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain G-alpha PF00503.20 OAG11832.1 - 0.0005 19.3 0.0 0.53 9.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 OAG11832.1 - 0.00061 19.4 0.0 0.86 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 OAG11832.1 - 0.0016 18.7 0.7 0.14 12.4 0.1 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 OAG11832.1 - 0.0016 18.0 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 OAG11832.1 - 0.0019 18.8 0.0 2.6 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG11832.1 - 0.0027 18.0 0.1 2 8.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 OAG11832.1 - 0.003 17.3 0.0 3.1 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain PRK PF00485.18 OAG11832.1 - 0.0036 17.1 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 OAG11832.1 - 0.0068 16.8 0.0 5 7.6 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_14 PF13173.6 OAG11832.1 - 0.0079 16.2 0.1 1.7 8.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 OAG11832.1 - 0.0079 16.4 1.1 4.1 7.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.17 OAG11832.1 - 0.011 15.4 0.9 40 3.9 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 OAG11832.1 - 0.024 14.3 0.7 6.4 6.4 0.0 3.2 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin PF02224.18 OAG11832.1 - 0.04 13.6 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 OAG11832.1 - 0.055 12.6 0.0 13 4.9 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 OAG11832.1 - 0.056 12.7 0.0 15 4.8 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin ABC_ATPase PF09818.9 OAG11832.1 - 0.069 11.9 0.7 8.5 5.0 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class dNK PF01712.19 OAG11832.1 - 0.072 12.9 0.0 9.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 OAG11832.1 - 0.13 12.2 0.0 16 5.4 0.0 3.2 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.21 OAG11832.1 - 0.15 11.4 0.1 25 4.2 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 OAG11832.1 - 0.23 11.0 1.2 51 3.4 0.0 3.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 OAG11832.1 - 0.58 9.9 2.9 28 4.4 0.0 3.2 2 1 0 2 2 2 0 AAA domain AT_hook PF02178.19 OAG11833.1 - 0.0029 17.3 30.1 0.8 9.8 1.1 4.3 3 0 0 3 3 3 3 AT hook motif GEN1_C PF18380.1 OAG11834.1 - 1e-28 100.3 1.1 2.2e-28 99.2 0.1 2.2 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 OAG11834.1 - 4.6e-24 84.6 0.0 8.9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OAG11834.1 - 1.5e-08 35.0 0.0 3.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 OAG11834.1 - 0.019 14.5 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing Tam41_Mmp37 PF09139.11 OAG11835.1 - 1.3e-120 402.8 0.0 1.5e-120 402.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF2856 PF11043.8 OAG11835.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) BIR PF00653.21 OAG11836.1 - 4.4e-45 152.2 0.4 1.4e-21 76.9 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain PRC2_HTH_1 PF18118.1 OAG11836.1 - 1.9 9.3 6.3 0.27 12.1 1.0 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain RhoGEF67_u1 PF16615.5 OAG11836.1 - 4.2 7.9 14.4 0.12 12.9 0.6 3.0 2 0 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 DEDD_Tnp_IS110 PF01548.17 OAG11837.1 - 0.18 11.7 0.7 0.33 10.8 0.7 1.3 1 0 0 1 1 1 0 Transposase PARP PF00644.20 OAG11838.1 - 1.2e-09 38.1 0.0 2.6e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 OAG11838.1 - 2.4e-08 33.7 0.0 7.5e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme S6PP_C PF08472.10 OAG11838.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal MIP PF00230.20 OAG11839.1 - 4.2e-48 164.0 3.7 5.3e-48 163.7 3.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein CDC45 PF02724.14 OAG11840.1 - 1.1e-236 787.1 0.0 1.5e-236 786.7 0.0 1.4 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 OAG11840.1 - 0.072 12.4 27.0 0.36 10.1 11.1 2.2 2 0 0 2 2 2 0 BUD22 CSRNP_N PF16019.5 OAG11840.1 - 0.25 11.3 3.5 0.75 9.7 3.5 1.8 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAM60A PF15396.6 OAG11840.1 - 0.51 10.3 9.5 0.033 14.2 1.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A TFIIA PF03153.13 OAG11840.1 - 3.8 7.4 14.1 0.036 14.1 3.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 OAG11840.1 - 6.9 6.8 23.7 4.2 7.5 8.9 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF3425 PF11905.8 OAG11841.1 - 8.9e-19 67.7 0.9 1.7e-18 66.8 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG11841.1 - 0.0005 20.1 13.3 0.00092 19.3 13.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG11841.1 - 0.0039 17.2 14.2 0.0088 16.1 14.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper GvpL_GvpF PF06386.11 OAG11841.1 - 0.16 11.9 1.0 0.22 11.4 1.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ADH_zinc_N PF00107.26 OAG11842.1 - 6.1e-11 42.4 1.4 8.3e-11 42.0 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG11842.1 - 7.2e-10 38.7 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG11842.1 - 0.032 15.3 0.2 0.096 13.7 0.2 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 OAG11842.1 - 0.058 12.9 0.9 0.091 12.2 0.2 1.7 2 0 0 2 2 2 0 short chain dehydrogenase RTA1 PF04479.13 OAG11843.1 - 8.6e-49 165.9 8.7 1.4e-48 165.3 8.7 1.3 1 0 0 1 1 1 1 RTA1 like protein PDR_assoc PF08370.11 OAG11843.1 - 0.016 15.0 4.1 2.7 7.8 0.1 2.6 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Ferric_reduct PF01794.19 OAG11844.1 - 1.2e-18 67.4 12.2 1.2e-18 67.4 12.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG11844.1 - 0.00017 21.6 0.2 0.00075 19.6 0.2 2.2 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG11844.1 - 0.001 19.2 0.1 1.7 8.8 0.1 2.7 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Gmad1 PF10647.9 OAG11844.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain TBP PF00352.21 OAG11845.1 - 4.8e-67 221.9 0.1 1.8e-32 111.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAG11845.1 - 5.4e-05 23.2 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAG11845.1 - 0.13 12.1 0.2 0.71 9.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) NICE-3 PF07406.11 OAG11846.1 - 0.036 14.0 0.1 0.087 12.8 0.0 1.7 2 0 0 2 2 2 0 NICE-3 protein NrfD PF03916.14 OAG11846.1 - 0.27 10.8 2.8 0.4 10.3 2.8 1.2 1 0 0 1 1 1 0 Polysulphide reductase, NrfD RRF PF01765.19 OAG11847.1 - 4.3e-31 108.1 0.0 5.6e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Myc-LZ PF02344.15 OAG11847.1 - 0.1 12.7 0.3 0.23 11.6 0.3 1.6 1 0 0 1 1 1 0 Myc leucine zipper domain DUF3498 PF12004.8 OAG11847.1 - 0.4 9.8 4.6 1.2 8.2 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3498) Nup96 PF12110.8 OAG11849.1 - 3.7e-76 256.0 0.5 5.6e-76 255.4 0.5 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OAG11849.1 - 6.5e-43 146.4 0.0 1.1e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 OAG11849.1 - 3e-24 85.7 343.1 5.9e-09 36.7 42.8 11.6 5 2 5 11 11 11 6 Nucleoporin FG repeat region Peptidase_S8_N PF16361.5 OAG11849.1 - 0.087 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal of Subtilase family EF-hand_1 PF00036.32 OAG11851.1 - 9.7e-24 81.1 9.4 6.3e-10 37.9 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OAG11851.1 - 3.3e-22 78.7 3.8 8.2e-14 51.8 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG11851.1 - 7.4e-20 69.1 6.5 1.2e-08 34.2 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OAG11851.1 - 2.6e-19 68.8 4.0 8.5e-11 41.5 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OAG11851.1 - 3.6e-18 64.1 6.8 1.1e-06 27.8 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 OAG11851.1 - 4.8e-07 29.7 0.6 0.0029 17.5 0.0 2.5 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OAG11851.1 - 0.00023 21.3 0.2 0.012 15.8 0.1 2.5 2 1 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 OAG11851.1 - 0.00028 21.2 0.9 0.081 13.3 0.3 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF4834 PF16118.5 OAG11851.1 - 0.00055 20.9 0.3 0.00055 20.9 0.3 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) EF-hand_9 PF14658.6 OAG11851.1 - 0.00055 20.2 0.1 0.23 11.8 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.13 OAG11851.1 - 0.00063 19.7 0.2 0.34 10.8 0.0 3.0 2 1 1 3 3 3 1 Caleosin related protein MgtE_N PF03448.17 OAG11851.1 - 0.029 15.0 2.7 5.5 7.6 1.6 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain Methyltransf_3 PF01596.17 OAG11851.1 - 0.046 12.9 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase SbsC_C PF18058.1 OAG11851.1 - 0.084 13.1 1.1 0.15 12.3 1.1 1.3 1 0 0 1 1 1 0 SbsC C-terminal domain DUF5633 PF18656.1 OAG11851.1 - 0.27 11.1 0.9 4.6 7.2 0.2 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5633) Complex1_51K PF01512.17 OAG11852.1 - 4.2e-47 159.8 0.0 7.1e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OAG11852.1 - 4e-29 100.5 1.4 5.1e-29 100.2 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OAG11852.1 - 1.1e-09 38.0 0.1 9.4e-09 35.0 0.0 2.4 2 0 0 2 2 2 1 SLBB domain DUF3568 PF12092.8 OAG11852.1 - 0.14 12.2 0.4 0.26 11.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) MAT1-1-2 PF17043.5 OAG11855.1 - 0.093 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function Ribosomal_60s PF00428.19 OAG11856.1 - 5.6e-11 42.9 0.3 5.6e-11 42.9 0.3 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein Baculo_11_kDa PF06143.11 OAG11857.1 - 0.061 12.9 0.9 0.16 11.6 0.9 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family zf-RING_2 PF13639.6 OAG11858.1 - 0.00037 20.8 3.0 0.0071 16.7 3.0 2.1 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG11858.1 - 0.00052 20.2 0.1 0.00076 19.7 0.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG11858.1 - 0.0026 17.6 1.3 0.049 13.5 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG11858.1 - 0.0063 16.1 1.4 0.0091 15.6 0.2 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAG11858.1 - 0.022 14.8 0.5 0.043 13.9 0.2 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 OAG11858.1 - 0.73 9.6 3.5 3.4 7.5 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger Pkinase PF00069.25 OAG11861.1 - 3.4e-65 220.1 0.0 4.4e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG11861.1 - 1.1e-32 113.4 0.0 4.1e-32 111.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG11861.1 - 0.00058 19.3 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG11861.1 - 0.00088 18.7 0.0 0.0044 16.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG11861.1 - 0.0013 17.7 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG11861.1 - 0.0061 16.5 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAG11861.1 - 0.0086 15.7 0.2 1.6 8.3 0.0 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 CDH-cyt PF16010.5 OAG11862.1 - 1.2e-51 175.0 2.5 2.8e-51 173.8 2.5 1.7 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 OAG11862.1 - 6.5e-31 107.8 0.0 1.4e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG11862.1 - 1.1e-07 31.8 0.1 0.00016 21.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG11862.1 - 1.3e-06 27.7 0.0 2.9e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG11862.1 - 8.1e-06 24.8 0.1 0.00028 19.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG11862.1 - 1.2e-05 25.4 2.1 1.5e-05 25.1 0.1 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG11862.1 - 2.6e-05 23.8 0.1 0.0026 17.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG11862.1 - 0.0016 17.7 0.0 0.017 14.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG11862.1 - 0.0045 16.3 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG11862.1 - 0.0056 16.0 0.3 0.009 15.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG11862.1 - 0.0094 16.5 0.4 0.04 14.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG11862.1 - 0.037 13.1 0.0 0.13 11.3 0.0 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein GMC_oxred_C PF05199.13 OAG11862.1 - 0.085 13.4 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 GMC oxidoreductase GIDA PF01134.22 OAG11862.1 - 0.15 11.1 0.2 0.66 9.0 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Peptidase_C13 PF01650.18 OAG11863.1 - 6.6e-42 143.8 0.2 8.9e-42 143.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family OPT PF03169.15 OAG11864.1 - 1e-155 519.9 20.8 1.2e-155 519.7 20.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 OAG11864.1 - 0.013 15.5 0.7 0.072 13.1 0.0 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S Phage_holin_2_3 PF16080.5 OAG11864.1 - 0.55 10.0 0.0 0.55 10.0 0.0 4.4 6 0 0 6 6 6 0 Bacteriophage holin family HP1 DUF4212 PF13937.6 OAG11864.1 - 0.7 10.3 0.0 0.7 10.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) p450 PF00067.22 OAG11865.1 - 8.4e-65 219.3 0.0 1.1e-64 218.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 OAG11866.1 - 0.0023 17.8 0.6 0.0077 16.1 0.6 2.0 1 1 0 1 1 1 1 F-box-like SWIB PF02201.18 OAG11867.1 - 4.9e-21 74.4 0.0 1.5e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain Amidohydro_1 PF01979.20 OAG11868.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG11868.1 - 0.0019 17.8 0.0 0.2 11.1 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Aldose_epim PF01263.20 OAG11871.1 - 2.8e-45 154.9 0.2 3.5e-45 154.6 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase MFS_1 PF07690.16 OAG11872.1 - 1.7e-18 66.7 29.1 1.7e-18 66.7 29.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG11872.1 - 6.3e-07 28.3 1.2 6.3e-07 28.3 1.2 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein UCR_hinge PF02320.16 OAG11873.1 - 5.1e-26 90.7 7.9 8.8e-26 89.9 7.9 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.13 OAG11873.1 - 0.033 14.1 5.0 0.036 14.0 5.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 OAG11873.1 - 0.87 7.8 4.0 0.82 7.9 4.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAG11873.1 - 4.9 5.2 11.7 5.1 5.2 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family RraA-like PF03737.15 OAG11874.1 - 6.7e-25 88.0 0.0 8.5e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA AFOR_N PF02730.15 OAG11874.1 - 0.065 13.1 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain ApbA PF02558.16 OAG11874.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Peptidase_M41 PF01434.18 OAG11875.1 - 8.8e-54 182.3 0.1 1.6e-53 181.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OAG11875.1 - 2e-43 147.9 0.0 4.1e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG11875.1 - 1.9e-07 30.7 0.1 4.3e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAG11875.1 - 5.2e-06 26.5 0.0 2.3e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG11875.1 - 1.6e-05 24.3 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OAG11875.1 - 6.5e-05 23.4 0.2 0.00081 19.8 0.2 2.6 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG11875.1 - 0.0002 21.7 0.0 0.045 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG11875.1 - 0.00041 20.0 0.3 0.2 11.2 0.1 2.7 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 OAG11875.1 - 0.00082 19.2 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OAG11875.1 - 0.0044 16.8 0.2 0.86 9.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAG11875.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 OAG11875.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG11875.1 - 0.018 14.4 0.2 0.041 13.3 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OAG11875.1 - 0.046 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAG11875.1 - 0.094 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.16 OAG11875.1 - 0.12 11.9 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 OAG11875.1 - 0.12 12.8 0.3 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OAG11875.1 - 0.12 11.7 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 OAG11875.1 - 0.12 12.9 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG11875.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OAG11875.1 - 0.17 11.3 0.0 0.82 9.2 0.0 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region Aminotran_1_2 PF00155.21 OAG11876.1 - 1.1e-50 172.8 0.0 1.3e-50 172.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAG11876.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Sugar_tr PF00083.24 OAG11877.1 - 1.7e-75 254.6 24.8 2e-75 254.4 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG11877.1 - 1.5e-20 73.4 33.5 1.5e-20 73.4 33.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 OAG11878.1 - 2.2e-55 187.8 0.0 7.2e-55 186.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG11878.1 - 3.3e-53 181.1 0.1 1.4e-52 179.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG11878.1 - 3e-22 78.5 0.4 1.1e-21 76.6 0.3 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 OAG11878.1 - 9.8e-08 31.9 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.11 OAG11878.1 - 0.0011 19.2 0.1 0.003 17.8 0.1 1.7 1 0 0 1 1 1 1 CARDB 5_nucleotid_C PF02872.18 OAG11879.1 - 4.4e-40 137.5 0.0 8.9e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OAG11879.1 - 6.7e-06 26.8 0.1 1.2e-05 25.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ING PF12998.7 OAG11880.1 - 0.00011 22.7 0.0 0.052 14.1 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 OAG11880.1 - 0.026 14.8 1.1 0.062 13.6 1.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Trans_reg_C PF00486.28 OAG11881.1 - 0.16 12.1 0.1 0.64 10.1 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal HSP70 PF00012.20 OAG11882.1 - 0.0014 16.9 0.1 0.049 11.8 0.0 2.5 2 1 0 2 2 2 2 Hsp70 protein DUF2500 PF10694.9 OAG11882.1 - 0.083 13.4 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Velvet PF11754.8 OAG11883.1 - 1.1e-42 146.7 0.8 5.5e-30 105.1 0.2 2.1 1 1 1 2 2 2 2 Velvet factor p450 PF00067.22 OAG11885.1 - 1.4e-44 152.6 0.0 1.8e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 OAG11886.1 - 5.2e-66 222.9 3.2 6.5e-66 222.6 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG11886.1 - 2.7e-21 76.2 0.0 4.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain YjbE PF11106.8 OAG11886.1 - 0.042 14.1 0.4 0.098 12.9 0.4 1.6 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE MOZ_SAS PF01853.18 OAG11887.1 - 1.4e-74 249.6 0.0 2e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAG11887.1 - 2.5e-19 68.6 3.6 6.1e-19 67.4 3.6 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 OAG11887.1 - 1.6e-08 34.5 9.2 1.6e-08 34.5 9.2 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 OAG11887.1 - 0.00037 20.3 8.8 0.00037 20.3 8.8 2.3 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 OAG11887.1 - 0.0054 16.6 0.3 0.017 15.0 0.3 1.9 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OAG11887.1 - 0.048 13.2 5.7 0.022 14.3 1.4 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 OAG11887.1 - 0.29 11.1 4.5 1.1 9.2 4.7 1.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 OAG11887.1 - 1.8 8.5 6.6 1.6 8.7 4.5 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 MWFE PF15879.5 OAG11888.1 - 1.9e-25 88.8 0.2 2.4e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Phostensin_N PF13916.6 OAG11888.1 - 0.067 13.5 0.2 0.087 13.2 0.2 1.2 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Acetyltransf_2 PF00797.17 OAG11889.1 - 6.3e-41 140.7 0.0 8.5e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Uds1 PF15456.6 OAG11890.1 - 1.2e-36 125.8 7.7 1.2e-36 125.8 7.7 7.5 4 2 2 6 6 6 1 Up-regulated During Septation DUF2935 PF11155.8 OAG11890.1 - 0.038 14.3 6.1 99 3.3 2.6 5.3 3 2 0 4 4 4 0 Domain of unknown function (DUF2935) Melibiase_2 PF16499.5 OAG11891.1 - 1.5e-54 185.1 4.1 3.5e-54 183.9 4.1 1.6 1 1 0 1 1 1 1 Alpha galactosidase A Ricin_B_lectin PF00652.22 OAG11891.1 - 5.3e-16 59.0 0.5 1.3e-15 57.8 0.5 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase_C PF17801.1 OAG11891.1 - 1.1e-15 57.4 1.6 3.1e-15 56.0 0.1 2.5 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain RicinB_lectin_2 PF14200.6 OAG11891.1 - 0.00036 21.2 1.4 0.24 12.2 0.0 3.9 1 1 2 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Melibiase PF02065.18 OAG11891.1 - 0.0014 17.7 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Melibiase ComK PF06338.11 OAG11891.1 - 0.041 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 ComK protein Ccdc124 PF06244.12 OAG11892.1 - 2.6e-25 89.4 23.7 2.6e-25 89.4 23.7 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Glyco_hydro_76 PF03663.14 OAG11894.1 - 7.9e-127 423.7 18.0 1e-126 423.3 18.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG11894.1 - 0.0082 15.3 7.9 0.16 11.0 0.1 2.8 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 DUF1631 PF07793.11 OAG11894.1 - 0.84 8.0 2.6 1.1 7.6 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Acyltransferase PF01553.21 OAG11895.1 - 6.2e-10 38.8 0.0 1.2e-08 34.7 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase DUF4220 PF13968.6 OAG11895.1 - 2.5 7.4 4.9 0.9 8.9 2.3 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) TauD PF02668.16 OAG11896.1 - 1.1e-33 117.2 0.3 1.6e-33 116.6 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 OAG11896.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 CsiD DUF3328 PF11807.8 OAG11897.1 - 1.9e-41 142.2 1.0 2.2e-41 142.1 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sox17_18_mid PF12067.8 OAG11898.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 Sox 17/18 central domain ENTH PF01417.20 OAG11899.1 - 7.4e-47 158.5 0.1 1.1e-46 157.9 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF4264 PF14084.6 OAG11899.1 - 0.00097 18.7 0.1 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.20 OAG11899.1 - 0.0011 18.7 9.3 0.0031 17.3 0.8 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 OAG11899.1 - 0.0039 16.2 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 ANTH domain APC_u15 PF16636.5 OAG11899.1 - 0.11 12.9 0.2 0.11 12.9 0.2 3.7 3 0 0 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 zf-C2H2 PF00096.26 OAG11901.1 - 1.1e-21 76.0 25.3 3.9e-05 23.9 1.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG11901.1 - 1.2e-17 63.4 26.8 1.8e-06 28.1 1.2 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG11901.1 - 5.2e-12 45.5 22.9 0.0044 17.7 1.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG11901.1 - 2e-06 27.9 0.7 2.5 8.5 0.0 4.8 5 0 0 5 5 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OAG11901.1 - 0.0023 17.6 9.2 0.021 14.6 0.8 3.5 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 OAG11901.1 - 0.01 16.2 11.8 1.9 9.0 0.0 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OAG11901.1 - 0.12 13.1 2.2 13 6.5 0.3 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf_UBZ PF18439.1 OAG11901.1 - 0.26 10.9 6.8 1.2 8.8 0.2 3.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 OAG11901.1 - 0.64 10.0 6.9 18 5.3 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DZR PF12773.7 OAG11901.1 - 1.2 9.2 8.3 87 3.3 8.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 OAG11901.1 - 1.5 9.0 9.2 3.4 7.9 1.1 3.2 1 1 3 4 4 4 0 Zinc ribbon domain IBR PF01485.21 OAG11901.1 - 1.7 8.9 9.8 14 6.0 0.1 3.2 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain DUF2256 PF10013.9 OAG11901.1 - 3 8.0 7.3 24 5.2 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.11 OAG11901.1 - 3.8 7.5 4.9 6.6 6.7 0.1 3.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger XPA_N PF01286.18 OAG11901.1 - 9.9 6.3 9.0 0.9 9.6 0.5 3.0 4 0 0 4 4 4 0 XPA protein N-terminal NAD_binding_1 PF00175.21 OAG11903.1 - 7e-12 46.0 0.0 1.6e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 OAG11903.1 - 2.2e-10 41.1 0.1 4.6e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 OAG11903.1 - 0.0027 17.6 0.3 0.005 16.8 0.3 1.4 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 OAG11903.1 - 0.0048 17.0 1.3 1.1 9.4 0.3 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain bZIP_2 PF07716.15 OAG11904.1 - 0.00013 21.9 6.4 0.00022 21.3 6.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAG11904.1 - 0.014 15.5 7.4 0.022 14.9 7.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor Phg_2220_C PF09524.10 OAG11904.1 - 0.05 13.7 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) INCENP_ARK-bind PF03941.15 OAG11905.1 - 6.4e-19 67.7 2.1 3.5e-18 65.3 2.1 2.4 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region RCR PF12273.8 OAG11906.1 - 0.0021 18.7 0.8 0.0036 18.0 0.0 1.8 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red FeoB_associated PF12669.7 OAG11906.1 - 0.011 16.1 0.2 0.011 16.1 0.2 2.7 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DUF5305 PF17231.2 OAG11906.1 - 0.021 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) BatD PF13584.6 OAG11906.1 - 0.036 12.9 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance RIFIN PF02009.16 OAG11906.1 - 0.063 13.2 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Rifin Protocadherin PF08374.11 OAG11906.1 - 0.063 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 OAG11906.1 - 0.098 13.6 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Med3 PF11593.8 OAG11906.1 - 1.4 8.0 3.2 2.7 7.1 3.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sod_Fe_C PF02777.18 OAG11909.1 - 3.2e-37 126.8 1.6 5.1e-37 126.1 0.3 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAG11909.1 - 1.7e-27 95.7 2.6 2.9e-27 95.0 2.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Acetyltransf_8 PF13523.6 OAG11910.1 - 3.2e-51 172.8 0.0 4.6e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PBP_N PF17093.5 OAG11910.1 - 0.011 16.0 3.6 0.011 16.0 3.6 1.9 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Acetyltransf_3 PF13302.7 OAG11910.1 - 0.14 12.8 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain XhlA PF10779.9 OAG11914.1 - 0.053 13.7 1.8 5.6 7.2 0.1 3.3 3 0 0 3 3 3 0 Haemolysin XhlA Mcm10 PF09332.11 OAG11914.1 - 4 6.8 11.6 0.15 11.5 1.3 2.9 3 0 0 3 3 3 0 Mcm10 replication factor GCFC PF07842.12 OAG11915.1 - 5.7e-38 131.1 0.5 8.6e-38 130.5 0.5 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 OAG11915.1 - 3.9e-13 49.0 6.2 8.6e-13 48.0 6.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAG11915.1 - 0.00042 20.3 2.0 0.00042 20.3 2.0 2.4 2 0 0 2 2 2 1 G-patch domain Fzo_mitofusin PF04799.13 OAG11915.1 - 0.069 12.7 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF1664 PF07889.12 OAG11915.1 - 0.093 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PvlArgDC PF01862.16 OAG11915.1 - 0.23 11.2 0.3 0.5 10.1 0.3 1.5 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) MARVEL PF01284.23 OAG11916.1 - 4.7e-29 101.3 11.8 5.6e-29 101.0 11.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain PSP1 PF04468.12 OAG11917.1 - 1.5e-23 82.9 1.1 2.6e-23 82.1 1.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Gastrin PF00918.17 OAG11918.1 - 0.08 13.9 0.8 0.15 13.0 0.8 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Ribosomal_L15e PF00827.17 OAG11919.1 - 1.8e-89 298.5 11.1 2.3e-89 298.2 11.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 FXMRP1_C_core PF12235.8 OAG11919.1 - 4.6 7.9 8.2 0.86 10.3 1.6 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal DnaJ PF00226.31 OAG11920.1 - 1.7e-21 76.1 0.4 3.6e-21 75.1 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain eIF3_subunit PF08597.10 OAG11921.1 - 0.084 12.8 30.6 0.2 11.5 30.6 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MRP-S26 PF14943.6 OAG11921.1 - 1.5 8.7 23.7 4.1 7.3 23.7 1.7 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 AAA_11 PF13086.6 OAG11921.1 - 3.1 7.5 10.9 5.9 6.6 10.9 1.4 1 0 0 1 1 1 0 AAA domain Vfa1 PF08432.10 OAG11921.1 - 3.4 8.0 21.0 7.4 6.9 21.0 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 OAG11921.1 - 4.7 5.4 19.3 6.7 4.9 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OAG11921.1 - 9.5 6.0 20.0 17 5.1 20.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BTB PF00651.31 OAG11922.1 - 0.0015 18.8 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain tRNA-synt_2b PF00587.25 OAG11923.1 - 3.3e-20 72.8 0.0 2.1e-19 70.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAG11923.1 - 1.4e-14 54.3 2.1 2.1e-14 53.6 2.1 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 OAG11923.1 - 0.044 13.6 6.0 0.36 10.6 0.3 2.4 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 OAG11923.1 - 0.068 13.6 3.0 3.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB TRAM_LAG1_CLN8 PF03798.16 OAG11924.1 - 6.6e-52 176.1 4.4 9.9e-52 175.6 4.4 1.3 1 0 0 1 1 1 1 TLC domain DUF3621 PF12285.8 OAG11924.1 - 0.044 14.1 0.6 0.077 13.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) Sensor PF13796.6 OAG11924.1 - 0.12 12.4 1.7 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Putative sensor Homeobox_KN PF05920.11 OAG11926.1 - 1.8e-14 53.3 1.5 4.2e-14 52.2 1.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAG11926.1 - 4.3e-09 36.1 0.7 4.3e-09 36.1 0.7 2.1 2 0 0 2 2 2 1 Homeodomain zinc_ribbon_15 PF17032.5 OAG11926.1 - 0.012 16.3 1.7 0.012 16.3 1.7 3.0 3 0 0 3 3 3 0 zinc-ribbon family YdaS_antitoxin PF15943.5 OAG11926.1 - 0.03 14.2 0.1 0.076 12.9 0.1 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT BIR PF00653.21 OAG11926.1 - 0.25 12.0 4.9 0.7 10.6 0.2 3.5 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain OrsD PF12013.8 OAG11926.1 - 2.2 8.7 8.3 2.1 8.8 0.5 3.3 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Auto_anti-p27 PF06677.12 OAG11926.1 - 3.1 8.0 9.5 0.79 9.9 1.4 2.7 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc-ribbons_6 PF07191.12 OAG11926.1 - 8.2 6.5 9.5 25 4.9 1.7 3.3 3 0 0 3 3 3 0 zinc-ribbons Abhydrolase_6 PF12697.7 OAG11927.1 - 4.6e-15 56.8 0.0 6.7e-14 53.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG11927.1 - 2.1e-12 47.2 0.0 1.9e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG11927.1 - 4e-06 26.3 0.0 2.2e-05 23.8 0.0 2.1 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF2959 PF11172.8 OAG11927.1 - 0.073 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) MFS_1 PF07690.16 OAG11928.1 - 5.7e-42 143.9 22.6 5.7e-42 143.9 22.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG11928.1 - 2.8e-08 33.1 4.0 2.8e-08 33.1 4.0 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 OAG11928.1 - 2.9e-06 25.9 6.8 5.4e-06 25.0 4.4 2.4 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ArsP_1 PF03773.13 OAG11928.1 - 0.00077 18.7 0.6 0.00077 18.7 0.6 2.0 2 0 0 2 2 2 1 Predicted permease DUF4452 PF14618.6 OAG11929.1 - 0.023 14.6 1.8 0.038 13.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) SF3b10 PF07189.11 OAG11930.1 - 1.8e-35 120.8 0.0 2e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Ank_3 PF13606.6 OAG11931.1 - 1.6e-08 34.1 0.7 0.0036 17.7 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG11931.1 - 1.6e-07 31.4 0.7 0.00038 20.7 0.1 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG11931.1 - 1.9e-07 31.6 0.1 7.7e-07 29.6 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG11931.1 - 9.3e-07 29.3 0.1 3.4e-05 24.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG11931.1 - 1.1e-06 28.8 0.1 0.031 14.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat TFIIS_C PF01096.18 OAG11932.1 - 7.2e-19 67.4 5.0 7.2e-19 67.4 5.0 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OAG11932.1 - 0.00073 19.4 9.9 0.017 15.0 0.4 3.5 4 0 0 4 4 4 2 RNA polymerases M/15 Kd subunit IBR PF01485.21 OAG11932.1 - 0.01 16.1 7.0 0.94 9.7 2.4 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 OAG11932.1 - 0.18 11.8 9.2 0.43 10.6 0.6 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 OAG11932.1 - 1.3 9.0 5.7 4 7.4 1.8 3.0 2 1 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 OAG11932.1 - 1.4 8.7 0.1 1.4 8.7 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 OAG11932.1 - 6.7 6.7 11.9 2.9 7.9 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 OAG11933.1 - 1.3 10.0 4.2 4.7 8.3 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.25 OAG11934.1 - 2.4e-15 56.5 0.0 1.5e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG11934.1 - 2.7e-09 36.9 0.0 7.4e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG11934.1 - 0.022 14.2 0.0 0.042 13.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG11934.1 - 0.045 13.6 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 KR domain Glyco_hydro_28 PF00295.17 OAG11935.1 - 1.9e-100 336.1 19.5 2.3e-100 335.8 19.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Het-C PF07217.11 OAG11936.1 - 0.07 11.7 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Peptidase_S9 PF00326.21 OAG11937.1 - 1.3e-16 60.7 0.0 1.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG11937.1 - 1.5e-09 37.9 0.0 0.00087 19.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG11937.1 - 2.1e-07 30.4 0.0 0.003 16.9 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 OAG11937.1 - 7e-06 25.7 0.0 1.6e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAG11937.1 - 4e-05 23.6 0.0 7.3e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 OAG11937.1 - 0.0013 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 OAG11937.1 - 0.037 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.16 OAG11937.1 - 0.038 13.8 0.1 2.6 7.8 0.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase NUDIX PF00293.28 OAG11938.1 - 1.4e-10 41.3 0.0 3.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 OAG11938.1 - 6.4e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) DUF4451 PF14616.6 OAG11941.1 - 5.3e-23 81.5 0.2 3.1e-22 79.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) DUF4097 PF13349.6 OAG11944.1 - 0.00034 20.1 9.2 0.011 15.0 8.6 2.6 1 1 1 2 2 2 2 Putative adhesin DUF2154 PF09922.9 OAG11944.1 - 0.05 13.5 0.0 4.7 7.1 0.0 2.6 1 1 0 2 2 2 0 Cell wall-active antibiotics response 4TMS YvqF CoA_transf_3 PF02515.17 OAG11946.1 - 2.8e-40 138.6 0.0 6e-40 137.5 0.0 1.5 2 0 0 2 2 2 1 CoA-transferase family III Spidroin_N PF16763.5 OAG11946.1 - 0.0098 15.9 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term DUF4599 PF15371.6 OAG11947.1 - 0.0072 16.8 4.0 0.0098 16.4 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4599) Fungal_trans PF04082.18 OAG11948.1 - 8.1e-24 84.1 0.1 1.5e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAG11949.1 - 7.9e-72 242.5 16.4 9.7e-72 242.2 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG11949.1 - 2.3e-27 95.9 26.8 5e-27 94.7 14.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.8 OAG11949.1 - 0.39 11.0 5.0 1 9.7 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) OATP PF03137.20 OAG11949.1 - 4.6 5.4 12.5 2.4 6.3 2.3 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family EBP PF05241.12 OAG11950.1 - 5.5e-07 29.2 1.8 7.9e-07 28.7 1.8 1.3 1 0 0 1 1 1 1 Emopamil binding protein Nucleotid_trans PF03407.16 OAG11953.1 - 1e-07 32.2 0.1 2e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 OAG11953.1 - 2.9e-06 27.2 2.1 9e-06 25.6 2.1 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Fungal_trans PF04082.18 OAG11954.1 - 5.8e-08 32.1 0.1 9.4e-08 31.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAP_N PF01213.19 OAG11954.1 - 3.6 7.0 5.3 5.8 6.3 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_tranf_2_3 PF13641.6 OAG11955.1 - 4e-25 89.0 0.0 7.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG11955.1 - 3.4e-10 40.2 0.6 3.4e-10 40.2 0.6 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG11955.1 - 0.00012 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG11955.1 - 0.028 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2196 PF09962.9 OAG11958.1 - 4.7e-23 80.9 0.7 8.5e-23 80.1 0.7 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Zn-C2H2_12 PF18112.1 OAG11958.1 - 3.7 8.1 6.5 15 6.1 0.3 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain TPR_1 PF00515.28 OAG11959.1 - 2.1e-40 134.9 13.7 2.6e-08 33.3 0.1 8.4 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAG11959.1 - 8.2e-36 119.2 14.7 3e-06 26.9 0.1 8.7 8 1 1 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.31 OAG11959.1 - 2.3e-27 94.9 4.3 7.3e-27 93.3 4.3 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 OAG11959.1 - 1.3e-26 92.0 9.3 1.7e-08 34.0 1.3 6.8 6 0 0 6 6 6 3 TPR repeat TPR_16 PF13432.6 OAG11959.1 - 2.7e-24 85.5 0.6 6.2e-05 23.6 0.2 6.0 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG11959.1 - 3.4e-23 81.9 13.1 6e-06 26.7 0.0 6.3 4 2 3 7 7 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG11959.1 - 2.6e-21 74.5 6.3 0.00034 21.2 0.1 8.4 4 3 5 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG11959.1 - 4.2e-21 73.3 5.4 0.0052 16.9 0.0 7.4 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAG11959.1 - 2.9e-15 56.3 8.7 0.037 14.3 0.1 6.9 6 1 0 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAG11959.1 - 1.1e-14 53.7 11.9 0.0051 17.1 0.1 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG11959.1 - 4e-13 49.4 2.4 0.00023 21.4 0.1 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAG11959.1 - 2.5e-12 46.8 0.3 0.058 13.5 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG11959.1 - 3.1e-12 45.6 3.6 0.95 9.6 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 OAG11959.1 - 1.4e-10 40.8 4.7 0.012 14.8 0.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAG11959.1 - 2.6e-09 37.1 7.6 0.41 11.4 0.2 7.2 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG11959.1 - 2.8e-09 36.5 6.4 0.24 11.3 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 OAG11959.1 - 5.4e-06 26.5 3.5 0.12 13.1 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG11959.1 - 1.7e-05 24.8 4.2 2.6 8.2 0.1 4.9 4 1 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 OAG11959.1 - 0.00018 21.8 9.1 0.69 10.3 0.2 5.0 3 3 2 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 OAG11959.1 - 0.00024 21.6 6.7 3.2 8.2 0.3 4.6 4 1 0 4 4 3 1 Bacterial transcriptional activator domain TPR_MalT PF17874.1 OAG11959.1 - 0.00056 19.4 0.8 0.058 12.8 0.0 3.1 2 1 1 3 3 3 2 MalT-like TPR region RRM_3 PF08777.11 OAG11959.1 - 0.0036 17.3 1.2 0.04 14.0 0.1 2.4 2 0 0 2 2 2 1 RNA binding motif FAT PF02259.23 OAG11959.1 - 0.022 14.0 3.5 0.21 10.8 2.7 2.2 1 1 1 2 2 2 0 FAT domain DUF3856 PF12968.7 OAG11959.1 - 0.022 14.8 4.5 13 5.8 0.1 5.0 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) DUF928 PF06051.12 OAG11959.1 - 0.084 12.7 0.1 0.58 10.0 0.0 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF928) Alkyl_sulf_dimr PF14863.6 OAG11959.1 - 0.12 12.9 1.7 25 5.3 0.1 3.6 3 1 0 3 3 2 0 Alkyl sulfatase dimerisation SRP_TPR_like PF17004.5 OAG11959.1 - 0.12 12.4 1.0 17 5.4 0.4 3.0 2 1 0 2 2 2 0 Putative TPR-like repeat SHNi-TPR PF10516.9 OAG11959.1 - 0.13 11.8 1.0 2.2e+02 1.4 0.0 5.0 6 0 0 6 6 6 0 SHNi-TPR MIT PF04212.18 OAG11959.1 - 1.1 9.3 5.7 38 4.5 0.0 4.2 3 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Yippee-Mis18 PF03226.14 OAG11960.1 - 2.6e-16 59.7 0.5 2.9e-16 59.6 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAG11960.1 - 0.00096 19.4 0.9 0.0014 18.9 0.9 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I RNA_POL_M_15KD PF02150.16 OAG11960.1 - 0.014 15.3 0.5 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-RRPl_C4 PF17026.5 OAG11960.1 - 0.063 13.4 1.8 0.41 10.8 1.3 2.0 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type ADH_N PF08240.12 OAG11961.1 - 3.4e-30 104.1 0.5 5.2e-30 103.5 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG11961.1 - 1.6e-15 57.2 0.0 2.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG11961.1 - 0.00052 19.6 0.0 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 OAG11961.1 - 0.00065 19.6 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated KH_1 PF00013.29 OAG11962.1 - 3.3e-41 138.9 9.8 2e-17 62.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAG11962.1 - 5.6e-10 38.9 11.0 0.0055 16.5 1.7 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 OAG11962.1 - 4e-09 36.2 5.5 0.029 14.3 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAG11962.1 - 7.7e-05 22.7 5.9 0.18 11.9 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain UAA PF08449.11 OAG11963.1 - 5.2e-45 153.9 11.3 7e-45 153.5 11.3 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 OAG11963.1 - 4e-06 26.2 2.5 0.0027 16.9 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 OAG11963.1 - 5.1e-06 26.7 27.5 0.017 15.3 10.9 3.6 2 2 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 OAG11963.1 - 0.022 14.1 7.5 0.065 12.6 0.5 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Sugar_tr PF00083.24 OAG11964.1 - 2.3e-97 326.7 19.5 2.6e-97 326.5 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG11964.1 - 3.5e-24 85.4 16.7 3.5e-24 85.4 16.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_32N PF00251.20 OAG11965.1 - 6.8e-26 91.5 0.0 2e-22 80.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Fungal_trans PF04082.18 OAG11966.1 - 3.3e-22 78.8 5.3 5.9e-22 78.0 5.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11966.1 - 8.2e-05 22.6 11.3 0.00013 22.0 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FdhD-NarQ PF02634.15 OAG11966.1 - 0.064 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 FdhD/NarQ family Cellulase PF00150.18 OAG11969.1 - 4.9e-12 45.9 0.1 6.6e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Whi5 PF08528.11 OAG11970.1 - 0.00069 19.2 0.0 0.0018 17.8 0.0 1.8 1 0 0 1 1 1 1 Whi5 like TOH_N PF12549.8 OAG11970.1 - 0.0031 17.3 0.1 6 6.8 0.0 4.0 3 0 0 3 3 3 2 Tyrosine hydroxylase N terminal Scs3p PF10261.9 OAG11972.1 - 1.6e-69 234.2 5.8 2.2e-69 233.7 5.8 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2627 PF11118.8 OAG11972.1 - 3.1 8.4 9.8 3.1 8.4 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) SLATT_4 PF18186.1 OAG11973.1 - 0.0022 17.7 0.3 0.98 9.0 0.0 2.4 2 0 0 2 2 2 2 SMODS and SLOG-associating 2TM effector domain family 4 Fungal_trans PF04082.18 OAG11973.1 - 0.0071 15.4 0.1 0.018 14.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_3 PF13606.6 OAG11974.1 - 0.0014 19.0 2.9 13 6.8 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OAG11974.1 - 0.0065 16.8 1.2 4.5 7.7 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG11974.1 - 0.032 14.8 0.1 7.9 7.1 0.0 3.8 2 1 2 4 4 4 0 Ankyrin repeats (3 copies) Glyco_hydro_61 PF03443.14 OAG11975.1 - 2.2e-55 187.8 0.0 2.6e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RHS_repeat PF05593.14 OAG11975.1 - 0.046 14.3 0.5 0.15 12.6 0.2 2.1 2 0 0 2 2 2 0 RHS Repeat SurE PF01975.17 OAG11976.1 - 3e-39 134.8 0.1 4.2e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE adh_short PF00106.25 OAG11977.1 - 2.6e-09 36.8 0.0 6.4e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG11977.1 - 5.4e-08 33.0 0.0 9.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG11977.1 - 5.2e-06 26.2 0.0 8.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glu_dehyd_C PF16912.5 OAG11977.1 - 0.025 14.1 0.0 0.063 12.8 0.0 1.8 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus PX PF00787.24 OAG11978.1 - 1.5e-12 47.5 0.0 6.9e-12 45.4 0.0 2.0 1 1 1 2 2 2 1 PX domain Carla_C4 PF01623.17 OAG11979.1 - 0.13 12.3 0.9 0.29 11.1 0.9 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein GDE_C PF06202.14 OAG11981.1 - 0.00016 20.8 2.6 0.0002 20.4 0.2 2.2 3 1 0 3 3 3 1 Amylo-alpha-1,6-glucosidase Lipase_GDSL_2 PF13472.6 OAG11982.1 - 1.6e-14 54.7 0.1 2.2e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG11982.1 - 2.9e-08 33.9 0.2 4.3e-08 33.4 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GSCFA PF08885.11 OAG11982.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 GSCFA family Epimerase PF01370.21 OAG11982.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phage_holin_2_1 PF04971.12 OAG11982.1 - 0.15 12.1 0.4 0.41 10.7 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage P21 holin S 2OG-FeII_Oxy_2 PF13532.6 OAG11983.1 - 1.2e-12 48.4 0.0 9.4e-11 42.3 0.0 2.0 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily LRR_6 PF13516.6 OAG11984.1 - 4.1e-12 45.1 14.2 0.00058 19.7 0.0 7.7 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 OAG11984.1 - 6.3e-12 45.2 0.1 1.3e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG11984.1 - 8.1e-11 41.5 0.1 2.5e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OAG11984.1 - 9.3e-06 25.9 7.6 1.6 9.3 0.3 5.4 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) PRANC PF09372.10 OAG11984.1 - 0.056 13.8 0.1 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 PRANC domain Adenyl_cycl_N PF12633.7 OAG11984.1 - 0.13 12.1 0.0 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase NT domain LRR_1 PF00560.33 OAG11984.1 - 1.1 10.1 20.8 5.9 7.9 0.2 6.9 7 1 0 7 7 7 0 Leucine Rich Repeat YecR PF13992.6 OAG11985.1 - 0.021 15.1 0.5 0.05 13.9 0.5 1.6 1 0 0 1 1 1 0 YecR-like lipoprotein DUF1772 PF08592.11 OAG11987.1 - 6.9e-28 97.7 1.4 6.9e-28 97.7 1.4 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF4149 PF13664.6 OAG11987.1 - 0.057 13.7 0.2 0.11 12.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) GST_N PF02798.20 OAG11988.1 - 1.5e-17 63.7 0.0 2.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG11988.1 - 5.3e-13 49.2 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG11988.1 - 2.3e-12 47.0 0.0 2e-11 44.0 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG11988.1 - 4.1e-10 39.7 0.0 6.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG11988.1 - 3.3e-09 36.8 0.0 5.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG11988.1 - 6.5e-07 29.3 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OAG11988.1 - 0.13 12.5 0.0 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein DUF3024 PF11225.8 OAG11990.1 - 0.021 15.0 0.0 0.072 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) DUF5131 PF07505.11 OAG11990.1 - 0.028 13.9 0.0 2.9 7.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF5131) Erf4 PF10256.9 OAG11990.1 - 0.031 14.4 0.0 0.086 13.0 0.0 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family ADH_N PF08240.12 OAG11991.1 - 6.9e-19 67.7 4.6 1.2e-18 66.9 4.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG11991.1 - 1e-14 54.6 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG11991.1 - 0.00013 21.4 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG11991.1 - 0.00015 21.2 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAG11991.1 - 0.023 14.6 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 OAG11991.1 - 0.1 11.9 1.5 0.2 11.0 1.5 1.4 1 0 0 1 1 1 0 ThiF family DSPc PF00782.20 OAG11992.1 - 3.2e-27 94.9 0.1 2e-24 85.9 0.1 2.4 1 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG11992.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_L4 PF00573.22 OAG11993.1 - 5.1e-38 130.7 0.6 6.7e-38 130.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OAG11993.1 - 8.3e-27 93.1 2.0 1.4e-26 92.3 1.0 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain TAFII28 PF04719.14 OAG11994.1 - 1.7e-24 85.7 0.1 6.6e-21 74.2 0.0 2.2 2 0 0 2 2 2 2 hTAFII28-like protein conserved region SKIP_SNW PF02731.15 OAG11995.1 - 6.8e-70 233.9 2.8 6.8e-70 233.9 2.8 2.8 3 0 0 3 3 3 1 SKIP/SNW domain FAM60A PF15396.6 OAG11995.1 - 2.7 7.9 6.9 7.3 6.5 6.9 1.7 1 0 0 1 1 1 0 Protein Family FAM60A DUF1852 PF08908.11 OAG11997.1 - 0.25 10.3 0.0 0.37 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) Fungal_trans_2 PF11951.8 OAG11998.1 - 5.2e-48 163.8 1.7 6.7e-48 163.4 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG11998.1 - 2.8e-06 27.3 8.0 5.1e-06 26.5 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3_C PF01915.22 OAG12000.1 - 1.7e-54 184.9 0.0 3.2e-54 184.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG12000.1 - 1.5e-34 119.8 0.0 3e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG12000.1 - 6.4e-16 58.2 0.1 1.2e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Forkhead PF00250.18 OAG12001.1 - 1e-34 118.6 0.2 1.8e-34 117.9 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OAG12001.1 - 8.8e-09 35.6 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ndufs5 PF10200.9 OAG12002.1 - 0.0062 16.8 0.0 0.0082 16.4 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 OAG12002.1 - 0.056 13.8 0.9 0.3 11.5 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX17 PF05051.13 OAG12002.1 - 0.07 13.5 0.3 0.12 12.7 0.3 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Herpes_HEPA PF03324.14 OAG12002.1 - 0.075 13.5 0.0 0.097 13.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein TonB_2 PF13103.6 OAG12003.1 - 0.021 15.1 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 TonB C terminal Acetyltransf_3 PF13302.7 OAG12005.1 - 1.6e-13 51.5 0.0 2e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG12005.1 - 4.3e-05 23.7 0.0 0.00058 20.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG12005.1 - 0.0041 17.1 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG12005.1 - 0.044 14.2 0.0 0.89 10.0 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Esterase_phd PF10503.9 OAG12006.1 - 4.5e-22 78.6 0.3 6.5e-22 78.1 0.3 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OAG12006.1 - 3.6e-05 23.3 0.9 6.8e-05 22.4 0.9 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 OAG12006.1 - 0.00028 20.4 0.2 0.00093 18.7 0.1 1.7 2 0 0 2 2 2 1 Serine carboxypeptidase Esterase PF00756.20 OAG12006.1 - 0.00034 20.3 1.7 0.0014 18.4 1.7 1.8 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.28 OAG12006.1 - 0.019 13.9 0.5 0.052 12.4 0.1 1.8 2 0 0 2 2 2 0 Carboxylesterase family DUF1993 PF09351.10 OAG12007.1 - 1.7e-27 96.5 0.0 2e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF3535 PF12054.8 OAG12008.1 - 4e-121 405.3 1.1 4.1e-120 402.0 0.2 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 OAG12008.1 - 3.1e-65 220.2 0.0 7.4e-65 219.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG12008.1 - 5.5e-20 71.8 0.1 3e-19 69.4 0.0 2.3 3 0 0 3 3 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 OAG12008.1 - 2.6e-17 61.4 10.1 0.23 11.8 0.0 9.1 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 OAG12008.1 - 1.3e-07 31.9 11.8 0.0035 17.7 0.2 7.0 7 0 0 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 OAG12008.1 - 5.5e-07 30.1 0.4 0.43 11.2 0.0 4.2 3 1 0 4 4 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OAG12008.1 - 1.1e-06 29.0 20.4 0.073 13.6 0.2 9.1 10 0 0 10 10 10 3 HEAT-like repeat TIP120 PF08623.10 OAG12008.1 - 1.2e-05 25.2 0.0 0.26 11.0 0.0 3.1 2 0 0 2 2 2 2 TATA-binding protein interacting (TIP20) ResIII PF04851.15 OAG12008.1 - 0.00031 20.8 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit Cnd1 PF12717.7 OAG12008.1 - 0.00039 20.5 0.4 0.067 13.2 0.0 4.3 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 OAG12008.1 - 0.0033 17.7 0.0 5.2 7.5 0.0 4.8 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 OAG12008.1 - 0.0036 16.9 0.2 2.3 7.7 0.1 3.5 2 2 1 3 3 3 1 CLASP N terminal adh_short_C2 PF13561.6 OAG12009.1 - 1.3e-44 152.6 0.1 1.5e-44 152.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG12009.1 - 5.2e-36 124.0 0.0 6.6e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG12009.1 - 1.7e-05 24.8 0.2 3.2e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG12009.1 - 1.8e-05 24.3 0.0 3.6e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG12009.1 - 0.0009 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG12009.1 - 0.0037 16.7 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG12009.1 - 0.0095 15.0 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 OAG12009.1 - 0.035 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG12009.1 - 0.079 13.1 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase RdRP PF05183.12 OAG12010.1 - 1.7e-173 578.4 0.0 2.2e-173 578.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Phospholip_A2_3 PF09056.11 OAG12011.1 - 3.9e-45 153.0 3.3 4.5e-45 152.8 3.3 1.0 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 MFS_1 PF07690.16 OAG12012.1 - 1.7e-34 119.3 22.1 2.8e-26 92.3 3.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG12012.1 - 5.8e-05 21.6 1.1 0.00025 19.5 0.0 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ARL6IP6 PF15062.6 OAG12012.1 - 0.16 12.1 0.1 0.42 10.8 0.1 1.7 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Ytp1 PF10355.9 OAG12013.1 - 6e-100 334.0 3.0 1.1e-99 333.1 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAG12013.1 - 7.4e-20 70.7 3.3 7.4e-20 70.7 3.3 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF1218 PF06749.12 OAG12013.1 - 0.1 13.1 18.4 0.78 10.3 0.7 5.1 5 1 0 5 5 5 0 Protein of unknown function (DUF1218) Curto_V3 PF07436.11 OAG12013.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.0 2 0 0 2 2 2 0 Curtovirus V3 protein Saf_2TM PF18303.1 OAG12013.1 - 2.1 7.9 7.5 2.7 7.6 0.4 3.4 3 2 0 3 3 3 0 SAVED-fused 2TM effector domain MFS_1 PF07690.16 OAG12017.1 - 1.1e-25 90.3 39.1 1.1e-25 90.3 39.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L6e PF01159.19 OAG12018.1 - 5.2e-36 123.6 0.6 6.1e-36 123.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e adh_short PF00106.25 OAG12020.1 - 2e-44 151.4 0.3 3.4e-44 150.7 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12020.1 - 2e-31 109.3 0.1 7.5e-31 107.5 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12020.1 - 1.1e-10 41.7 2.6 3.4e-10 40.1 2.6 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG12020.1 - 0.0073 15.7 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAG12020.1 - 0.071 12.6 0.3 0.19 11.1 0.3 1.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sds3 PF08598.11 OAG12021.1 - 1.4e-39 136.3 0.0 9.5e-39 133.6 0.1 1.9 1 1 1 2 2 2 1 Sds3-like CdiA_C_tRNase PF18664.1 OAG12021.1 - 0.00062 19.9 0.1 0.0013 18.9 0.1 1.5 1 0 0 1 1 1 1 CdiA C-terminal tRNase domain DUF745 PF05335.13 OAG12021.1 - 1.2 8.9 6.3 3 7.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Thiolase_N PF00108.23 OAG12023.1 - 9.4e-88 293.9 0.4 1.3e-87 293.5 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG12023.1 - 2.4e-37 127.3 2.2 7.5e-37 125.7 0.9 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG12023.1 - 2.9e-07 30.3 1.7 4.2e-06 26.5 1.7 2.4 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAG12023.1 - 0.0036 17.1 0.2 0.86 9.5 0.0 2.8 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GldH_lipo PF14109.6 OAG12025.1 - 0.046 14.5 0.0 0.066 14.0 0.0 1.3 1 0 0 1 1 1 0 GldH lipoprotein His_Phos_1 PF00300.22 OAG12027.1 - 0.0022 17.7 1.3 4 7.1 0.0 3.4 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) SDF PF00375.18 OAG12028.1 - 2.4e-84 283.6 39.3 3.1e-84 283.3 39.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Neurensin PF14927.6 OAG12028.1 - 0.32 10.7 0.1 0.32 10.7 0.1 3.1 4 0 0 4 4 4 0 Neurensin PrmA PF06325.13 OAG12029.1 - 1.4e-13 50.9 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OAG12029.1 - 8.1e-11 41.9 0.0 1.7e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG12029.1 - 1.1e-10 42.1 0.0 2.7e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG12029.1 - 3.6e-08 33.9 0.0 1e-07 32.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG12029.1 - 9.4e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG12029.1 - 1.4e-06 27.9 0.1 2.6e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OAG12029.1 - 7.9e-06 25.9 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG12029.1 - 4.4e-05 22.9 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 OAG12029.1 - 0.00018 21.7 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 OAG12029.1 - 0.00027 20.7 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 OAG12029.1 - 0.0004 20.1 0.1 0.00073 19.2 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 OAG12029.1 - 0.00043 20.1 0.0 0.0007 19.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 OAG12029.1 - 0.00089 20.3 0.0 0.0038 18.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain zf-C2H2_2 PF12756.7 OAG12029.1 - 0.002 18.4 0.2 0.0039 17.5 0.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_12 PF08242.12 OAG12029.1 - 0.0028 18.4 0.2 0.0088 16.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG12029.1 - 0.0056 15.6 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 OAG12029.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAG12029.1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 OAG12029.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 OAG12029.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OAG12029.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PRMT5 PF05185.16 OAG12029.1 - 0.032 14.1 0.2 0.089 12.6 0.2 1.7 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_3 PF01596.17 OAG12029.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.18 OAG12029.1 - 0.13 11.9 0.0 0.41 10.3 0.1 1.8 2 1 0 2 2 1 0 Putative RNA methylase family UPF0020 zf-Di19 PF05605.12 OAG12029.1 - 0.16 12.3 1.9 0.29 11.5 1.9 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Rav1p_C PF12234.8 OAG12030.1 - 2.6e-272 904.9 0.0 4e-272 904.3 0.0 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal Terpene_synth_C PF03936.16 OAG12031.1 - 0.0011 18.4 0.0 0.0024 17.2 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 OAG12032.1 - 5.1e-63 213.4 0.0 6.8e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_topoisoIV PF00521.20 OAG12033.1 - 5.6e-127 424.2 0.0 1.1e-126 423.2 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OAG12033.1 - 7.9e-51 171.7 1.5 7.9e-51 171.7 1.5 2.3 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OAG12033.1 - 7.7e-28 97.1 3.4 2.1e-27 95.7 3.4 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OAG12033.1 - 6.2e-14 52.4 0.1 1.5e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OAG12033.1 - 2.5e-08 34.1 0.0 1.5e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 Toprim domain Ste5_C PF12194.8 OAG12033.1 - 0.057 13.4 2.1 0.097 12.6 0.6 2.0 2 0 0 2 2 2 0 Protein kinase Fus3-binding Ntox17 PF15524.6 OAG12033.1 - 0.2 11.9 2.3 0.46 10.8 0.2 2.7 3 0 0 3 3 3 0 Novel toxin 17 NusA_N PF08529.11 OAG12033.1 - 3.8 7.9 6.7 0.45 10.9 0.1 2.9 3 0 0 3 3 3 0 NusA N-terminal domain DMRT-like PF15791.5 OAG12034.1 - 0.2 12.1 4.2 2.9 8.3 0.5 2.7 3 0 0 3 3 3 0 Doublesex-and mab-3-related transcription factor C1 and C2 GST_N_3 PF13417.6 OAG12035.1 - 5.1e-14 52.4 0.0 8.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG12035.1 - 1.1e-11 45.0 0.0 2.3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG12035.1 - 1.1e-11 44.9 0.0 1.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OAG12035.1 - 1.4e-05 25.2 0.0 3.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 OAG12035.1 - 0.00046 20.2 0.0 0.00088 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG12035.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG12035.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-met PF12874.7 OAG12036.1 - 2.2e-07 31.0 0.1 6e-07 29.6 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG12036.1 - 1.5e-06 28.3 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 OAG12036.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-DBF PF07535.12 OAG12036.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 DBF zinc finger FliP PF00813.20 OAG12037.1 - 0.26 11.2 0.0 0.34 10.8 0.0 1.1 1 0 0 1 1 1 0 FliP family MFS_1 PF07690.16 OAG12038.1 - 4.8e-17 61.9 11.7 7.8e-17 61.2 11.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG12038.1 - 4.5e-05 22.5 1.7 4.5e-05 22.5 1.7 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter IPU_b_solenoid PF18783.1 OAG12038.1 - 0.022 14.8 0.3 0.052 13.6 0.3 1.6 1 0 0 1 1 1 0 Isopullulanase beta-solenoid repeat YoqO PF14037.6 OAG12038.1 - 0.035 14.6 0.0 0.45 11.1 0.1 2.5 2 0 0 2 2 2 0 YoqO-like protein DUF308 PF03729.13 OAG12038.1 - 0.37 11.2 5.7 1.6 9.1 5.7 2.2 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Homeobox_KN PF05920.11 OAG12039.1 - 2e-16 59.6 0.0 4.4e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAG12039.1 - 5.1e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 OAG12039.1 - 0.0012 18.8 0.1 0.0057 16.7 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 OAG12039.1 - 0.003 18.3 2.0 0.003 18.3 2.0 5.9 7 0 0 7 7 7 1 C2H2-type zinc finger DnaJ PF00226.31 OAG12042.1 - 4.1e-23 81.3 2.5 1.2e-22 79.8 2.5 1.9 1 0 0 1 1 1 1 DnaJ domain Inv-AAD PF18785.1 OAG12043.1 - 9e-61 203.4 0.3 1e-60 203.2 0.3 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 OAG12043.1 - 1.5e-13 50.5 0.0 2.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 OAG12043.1 - 0.0056 16.6 0.0 0.0061 16.5 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 OAG12043.1 - 0.01 15.9 0.0 0.036 14.1 0.0 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase MafB19-deam PF14437.6 OAG12043.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.5 1 1 0 1 1 1 0 MafB19-like deaminase DUF1295 PF06966.12 OAG12044.1 - 1.4e-39 136.0 0.2 2.9e-37 128.4 0.2 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAG12044.1 - 0.00035 20.6 0.1 0.002 18.1 0.0 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OAG12044.1 - 0.0074 16.7 0.0 0.027 14.9 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAG12044.1 - 0.017 15.5 0.0 0.23 11.9 0.0 2.7 2 1 1 3 3 3 0 Phospholipid methyltransferase PNTB PF02233.16 OAG12044.1 - 0.03 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit ERG4_ERG24 PF01222.17 OAG12044.1 - 0.088 11.6 0.0 0.2 10.4 0.0 1.5 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Apc15p PF05841.11 OAG12045.1 - 0.2 12.4 0.0 0.43 11.4 0.0 1.5 1 0 0 1 1 1 0 Apc15p protein Sec3_C PF09763.9 OAG12046.1 - 7.6e-215 715.4 4.4 9.9e-215 715.1 4.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 OAG12046.1 - 2.6e-24 85.2 0.3 4.6e-24 84.3 0.3 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 OAG12046.1 - 0.00087 18.1 0.4 0.0018 17.1 0.4 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C_2 PF15278.6 OAG12046.1 - 0.0094 16.3 0.3 0.037 14.4 0.3 2.0 1 0 0 1 1 1 1 Sec3 exocyst complex subunit GAS PF13851.6 OAG12046.1 - 0.044 13.1 0.6 0.13 11.5 0.6 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.6 OAG12046.1 - 0.092 13.1 1.3 0.27 11.6 0.3 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 SRP40_C PF05022.12 OAG12047.1 - 3.5e-22 79.0 1.5 1.8e-21 76.8 1.5 2.3 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.11 OAG12047.1 - 0.0015 18.4 0.2 0.0028 17.5 0.2 1.4 1 0 0 1 1 1 1 LisH Complex1_LYR_2 PF13233.6 OAG12048.1 - 1.8e-21 76.7 0.0 2.3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like FERM_M PF00373.18 OAG12048.1 - 0.013 15.9 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 FERM central domain MMR_HSR1 PF01926.23 OAG12049.1 - 1.5e-16 60.5 0.0 2.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG12049.1 - 0.00011 22.3 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 OAG12049.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG12049.1 - 0.0024 17.8 0.1 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OAG12049.1 - 0.007 15.9 0.0 0.027 14.0 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 OAG12049.1 - 0.03 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CPSF73-100_C PF11718.8 OAG12050.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Mitofilin PF09731.9 OAG12050.1 - 0.19 10.6 4.9 0.23 10.3 4.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.12 OAG12050.1 - 1.6 8.5 7.6 2.5 7.9 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 OAG12050.1 - 2.3 6.8 3.5 2.3 6.8 3.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GMC_oxred_C PF05199.13 OAG12052.1 - 0.00031 21.3 0.0 0.0004 20.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase HEPN_DZIP3 PF18738.1 OAG12052.1 - 0.02 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN Stn1 PF10451.9 OAG12053.1 - 1.5e-13 50.3 1.0 2.4e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 OAG12053.1 - 0.0057 16.6 0.5 0.034 14.1 0.5 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Granulin PF00396.18 OAG12054.1 - 4.3 7.8 19.8 4.8 7.6 9.6 2.5 1 1 1 2 2 2 0 Granulin SnoaL_2 PF12680.7 OAG12055.1 - 2.5e-06 28.1 0.0 3.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 OAG12055.1 - 0.15 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Aminotran_1_2 PF00155.21 OAG12056.1 - 3.5e-36 125.2 0.0 4.6e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II V_ATPase_I PF01496.19 OAG12057.1 - 0 1046.5 0.0 0 1046.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.21 OAG12057.1 - 0.00037 20.2 1.9 0.42 10.1 0.2 2.2 2 0 0 2 2 2 2 Intermediate filament protein CheZ PF04344.13 OAG12057.1 - 0.0057 16.6 1.0 0.043 13.7 0.1 2.3 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ Sec63 PF02889.16 OAG12058.1 - 1.5e-32 112.8 0.0 2.4e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OAG12058.1 - 3.6e-22 79.0 0.0 6.7e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG12058.1 - 8.4e-12 45.4 0.0 2.1e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG12058.1 - 3e-07 30.7 0.0 1e-06 29.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG12058.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 OAG12058.1 - 0.047 13.2 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 OAG12058.1 - 0.056 13.8 0.0 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Nuc_sug_transp PF04142.15 OAG12059.1 - 1.1e-109 366.5 12.8 1.2e-109 366.3 12.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OAG12059.1 - 0.00021 21.5 4.7 0.00021 21.5 4.7 2.7 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 OAG12059.1 - 0.0059 16.0 13.0 0.17 11.2 0.7 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 OAG12059.1 - 0.017 14.3 16.2 0.05 12.8 5.4 2.3 1 1 0 2 2 2 0 UAA transporter family TMEM234 PF10639.9 OAG12059.1 - 2.4 8.2 10.0 0.098 12.7 0.8 2.8 3 0 0 3 3 3 0 Putative transmembrane family 234 TFA2_Winged_2 PF18121.1 OAG12060.1 - 2.2e-17 62.5 1.4 2.2e-17 62.5 1.4 1.8 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 OAG12060.1 - 5.1e-14 52.3 1.3 5.1e-14 52.3 1.3 2.2 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF4689 PF15755.5 OAG12060.1 - 0.23 11.0 1.6 2.5 7.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4689) Methyltransf_23 PF13489.6 OAG12061.1 - 1.2e-20 74.0 0.0 1.8e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG12061.1 - 2.7e-17 63.2 0.0 4.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG12061.1 - 4.8e-14 52.8 0.0 8.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG12061.1 - 1.1e-13 51.2 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG12061.1 - 2.4e-13 50.7 0.0 4.2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG12061.1 - 4.4e-05 22.6 0.0 6.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 OAG12061.1 - 4.5e-05 23.0 0.0 7.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG12061.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 OAG12061.1 - 0.028 13.7 0.0 0.063 12.6 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OAG12061.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MRP-L27 PF09809.9 OAG12062.1 - 4.1e-12 45.9 0.3 5.5e-12 45.5 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SIP1 PF04938.12 OAG12062.1 - 0.084 12.6 0.4 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Utp14 PF04615.13 OAG12063.1 - 1.5e-199 665.3 67.8 1.5e-199 665.3 67.8 2.3 1 1 1 2 2 2 1 Utp14 protein DUF4786 PF16027.5 OAG12063.1 - 0.088 13.4 3.6 0.44 11.1 3.6 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) Glyco_hydro81C PF17652.1 OAG12064.1 - 3e-142 474.0 0.9 4.7e-130 433.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OAG12064.1 - 3e-86 289.5 0.0 3.9e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 OAG12065.1 - 4.9e-45 153.2 34.1 1.3e-23 83.6 16.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Baculo_PEP_C PF04513.12 OAG12067.1 - 0.15 12.1 4.7 1.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_S7 PF00177.21 OAG12069.1 - 6.7e-26 90.7 0.0 1.1e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.26 OAG12070.1 - 6.7e-21 75.3 0.5 2.4e-19 70.2 0.5 2.5 1 1 0 1 1 1 1 Universal stress protein family Hepatitis_core PF00906.20 OAG12070.1 - 0.18 11.3 0.9 0.45 10.0 0.9 1.6 1 0 0 1 1 1 0 Hepatitis core antigen HET PF06985.11 OAG12071.1 - 5.3e-17 62.5 0.0 8.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec1 PF00995.23 OAG12072.1 - 2.9e-125 419.7 0.0 3.3e-125 419.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH PF00642.24 OAG12073.1 - 1.3e-06 28.2 1.4 2.4e-06 27.3 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG12073.1 - 6.2e-06 26.1 4.1 1.1e-05 25.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 OAG12073.1 - 0.0022 17.7 1.6 0.0042 16.9 1.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OAG12073.1 - 0.0083 16.6 5.7 0.018 15.5 5.7 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OAG12073.1 - 0.0088 16.7 2.1 0.013 16.2 0.5 2.1 2 0 0 2 2 2 1 Torus domain Med26 PF08711.11 OAG12073.1 - 0.048 13.7 0.6 0.14 12.2 0.6 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain PBP1_TM PF14812.6 OAG12073.1 - 3.1 8.2 13.0 0.11 12.8 2.0 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Btz PF09405.10 OAG12074.1 - 2.2e-28 99.1 2.3 5.6e-28 97.8 2.3 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding UQ_con PF00179.26 OAG12075.1 - 7.4e-43 145.6 0.0 8.3e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG12075.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B Kelch_5 PF13854.6 OAG12077.1 - 2.3e-10 40.2 0.5 2.3e-10 40.2 0.5 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 OAG12077.1 - 7.1e-06 26.2 2.9 0.0023 18.2 0.1 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG12077.1 - 0.012 15.6 6.3 0.024 14.6 0.1 3.7 3 1 0 3 3 3 0 Galactose oxidase, central domain SKG6 PF08693.10 OAG12077.1 - 0.11 11.9 0.2 0.28 10.6 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain IPTL-CTERM PF18203.1 OAG12077.1 - 0.3 11.0 5.2 0.61 10.1 5.2 1.5 1 0 0 1 1 1 0 IPTL-CTERM motif CTP_transf_1 PF01148.20 OAG12078.1 - 0.0023 17.8 3.3 0.0036 17.1 3.4 1.3 1 1 0 1 1 1 1 Cytidylyltransferase family DUF3984 PF13136.6 OAG12078.1 - 0.037 13.4 3.7 0.055 12.9 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DEAD PF00270.29 OAG12079.1 - 2.4e-38 131.7 0.0 2.6e-37 128.3 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG12079.1 - 1e-20 74.1 0.0 2.8e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG12079.1 - 4.4e-20 71.7 0.0 8.2e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SUR7 PF06687.12 OAG12081.1 - 0.072 12.7 0.8 0.11 12.1 0.8 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF3357 PF11837.8 OAG12081.1 - 0.12 12.8 0.3 0.46 11.0 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3792 PF12670.7 OAG12081.1 - 0.31 11.2 5.3 0.52 10.5 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF2157 PF09925.9 OAG12084.1 - 3.3 7.5 6.1 1.8 8.3 1.3 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Response_reg PF00072.24 OAG12085.1 - 2.8e-23 82.2 0.0 3.3e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain PsiA PF06952.11 OAG12085.1 - 0.045 13.0 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 PsiA protein Glyco_hydro_62 PF03664.13 OAG12086.1 - 1e-54 185.7 1.9 1.4e-54 185.3 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Epimerase PF01370.21 OAG12087.1 - 1.4e-16 60.7 0.0 2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG12087.1 - 1.8e-09 37.0 0.0 4.4e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG12087.1 - 5.2e-08 32.4 0.0 2.3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG12087.1 - 9.8e-08 32.1 0.4 1.8e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG12087.1 - 8.8e-05 22.1 0.0 0.00018 21.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG12087.1 - 0.0012 18.5 0.0 0.042 13.4 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 OAG12087.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fun_ATP-synt_8 PF05933.13 OAG12088.1 - 1.3e-19 70.1 7.3 1.7e-19 69.7 7.3 1.2 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) DUF3671 PF12420.8 OAG12088.1 - 0.076 13.1 0.2 0.093 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function GTP_EFTU PF00009.27 OAG12089.1 - 6.4e-55 185.7 0.1 1e-54 185.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG12089.1 - 9.6e-42 141.8 0.0 2.1e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG12089.1 - 2.4e-14 53.4 2.3 2.4e-14 53.4 2.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG12089.1 - 0.00067 19.7 0.1 0.018 15.1 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 OAG12089.1 - 0.19 11.7 4.1 0.077 12.9 1.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 adh_short PF00106.25 OAG12091.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.25 OAG12094.1 - 1.2e-56 192.1 0.0 1.6e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12094.1 - 2.2e-20 73.1 0.0 3.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG12094.1 - 6.6e-07 28.9 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAG12094.1 - 3.2e-05 23.0 0.1 7.8e-05 21.8 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG12094.1 - 0.00082 19.4 0.2 0.13 12.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OAG12094.1 - 0.00085 19.0 0.4 0.0022 17.7 0.4 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OAG12094.1 - 0.0022 16.8 0.3 0.0061 15.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase CDH-cyt PF16010.5 OAG12096.1 - 4.3e-25 88.4 5.8 8.2e-25 87.5 5.8 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAG12096.1 - 0.00031 20.9 13.8 0.00059 20.0 13.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 OAG12096.1 - 0.0016 18.2 4.5 0.0038 17.0 4.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4199 PF13858.6 OAG12096.1 - 5.2 7.4 9.2 7.5 6.9 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) EB1 PF03271.17 OAG12097.1 - 2.9e-18 65.8 1.6 5.4e-18 64.9 1.6 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 OAG12097.1 - 8.8e-07 29.1 0.9 1.6e-06 28.2 0.3 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 OAG12097.1 - 0.04 14.0 0.2 0.064 13.4 0.2 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein Syja_N PF02383.18 OAG12097.1 - 0.045 13.1 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Herpes_capsid PF06112.11 OAG12097.1 - 0.057 13.5 0.1 0.099 12.7 0.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Suppressor_APC PF11414.8 OAG12097.1 - 0.12 12.5 0.4 0.26 11.4 0.4 1.6 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Abhydrolase_6 PF12697.7 OAG12098.1 - 4.6e-16 60.1 0.1 7.4e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG12098.1 - 8.5e-16 58.4 0.4 4.1e-09 36.4 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG12098.1 - 1.4e-08 34.3 0.0 2.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LMWSLP_N PF12211.8 OAG12098.1 - 0.035 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal HET PF06985.11 OAG12099.1 - 2.2e-12 47.5 0.0 6.3e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF244 PF03112.14 OAG12099.1 - 0.066 13.1 0.2 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF DnaJ PF00226.31 OAG12100.1 - 1.7e-17 63.3 0.7 3.7e-17 62.2 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 OAG12101.1 - 5.8e-12 46.5 0.2 1e-11 45.8 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG12101.1 - 4.2e-06 27.1 0.7 0.00035 20.8 0.7 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ADC PF06314.11 OAG12102.1 - 0.00011 21.8 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Allexi_40kDa PF05549.11 OAG12104.1 - 0.065 12.7 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein zn-ribbon_14 PF16503.5 OAG12105.1 - 1.9e-18 65.7 4.0 1.9e-18 65.7 4.0 3.8 4 0 0 4 4 4 2 Zinc-ribbon ATP_bind_3 PF01171.20 OAG12105.1 - 2.4e-17 63.3 0.0 3.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 OAG12105.1 - 0.0091 15.5 0.9 0.0091 15.5 0.9 3.4 4 0 0 4 4 4 1 RecR protein zf-UBR PF02207.20 OAG12105.1 - 0.32 11.2 6.6 1.2 9.4 0.7 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_31 PF01055.26 OAG12106.1 - 2.6e-151 504.7 12.0 3.3e-151 504.4 12.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG12106.1 - 4.9e-37 126.7 0.2 1e-36 125.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG12106.1 - 8.9e-12 45.2 1.4 8.9e-12 45.2 1.4 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like p450 PF00067.22 OAG12107.1 - 5e-43 147.5 0.0 6.4e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cutinase PF01083.22 OAG12108.1 - 2.8e-26 92.5 2.4 3.6e-26 92.2 2.4 1.1 1 0 0 1 1 1 1 Cutinase Amidohydro_2 PF04909.14 OAG12109.1 - 3e-28 99.5 1.6 8.6e-28 98.0 1.6 1.7 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 OAG12109.1 - 0.2 11.0 0.0 1.1 8.6 0.0 2.1 1 1 0 1 1 1 0 TatD related DNase Acid_PPase PF12689.7 OAG12110.1 - 1.1e-61 207.5 0.0 1.3e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 OAG12110.1 - 0.059 13.1 0.0 0.092 12.5 0.0 1.3 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase adh_short PF00106.25 OAG12112.1 - 1.5e-39 135.5 0.0 2.1e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12112.1 - 6.7e-27 94.5 0.0 1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12112.1 - 4.3e-10 39.8 0.8 1.4e-09 38.2 0.8 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG12112.1 - 4.9e-06 26.2 0.1 8.9e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG12112.1 - 0.0057 15.7 0.0 0.0086 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 OAG12112.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1815 PF08844.10 OAG12112.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) GTP1_OBG PF01018.22 OAG12113.1 - 5.7e-40 136.4 0.3 2.3e-30 105.3 1.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 OAG12113.1 - 7.9e-24 83.9 0.0 1.9e-23 82.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG12113.1 - 9.5e-08 31.7 0.0 2.6e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG12113.1 - 0.021 14.9 0.1 13 5.8 0.0 3.0 2 1 1 3 3 3 0 Dynamin family MeaB PF03308.16 OAG12113.1 - 0.026 13.5 0.4 0.76 8.7 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 OAG12113.1 - 0.031 13.8 0.0 0.77 9.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 OAG12113.1 - 0.036 13.5 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 OAG12113.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 OAG12113.1 - 0.31 11.6 0.0 0.31 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.21 OAG12114.1 - 1.3e-60 205.5 0.0 1.7e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SurE PF01975.17 OAG12115.1 - 3e-19 69.6 0.0 3.8e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Thg1 PF04446.12 OAG12117.1 - 8.9e-37 125.9 0.3 1.2e-36 125.4 0.3 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase L27_1 PF09058.10 OAG12119.1 - 0.07 13.1 0.3 0.51 10.4 0.0 2.4 2 0 0 2 2 2 0 L27_1 SLAC1 PF03595.17 OAG12120.1 - 6.4e-85 285.3 51.0 7.3e-85 285.1 51.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Kinesin PF00225.23 OAG12122.1 - 1.3e-112 376.0 0.5 3.4e-112 374.7 0.5 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG12122.1 - 2.3e-26 92.5 0.1 8.8e-26 90.6 0.1 2.1 1 0 0 1 1 1 1 Microtubule binding ERG2_Sigma1R PF04622.12 OAG12122.1 - 0.022 14.1 0.0 0.098 12.0 0.0 2.1 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein Phage_rep_O PF04492.13 OAG12122.1 - 0.026 15.1 0.1 0.13 12.8 0.1 2.2 1 0 0 1 1 1 0 Bacteriophage replication protein O UQ_con PF00179.26 OAG12124.1 - 3.5e-51 172.5 0.0 4e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG12124.1 - 0.0045 16.7 0.0 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Sulfatase PF00884.23 OAG12125.1 - 6.3e-54 183.4 0.1 8.5e-54 183.0 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 OAG12125.1 - 1.7e-22 79.0 3.0 2.1e-22 78.7 0.8 2.2 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 OAG12125.1 - 1.2e-06 28.4 0.3 1.4e-05 24.9 0.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OAG12125.1 - 0.0044 17.8 0.0 0.014 16.1 0.0 1.8 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 OAG12125.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF4720 PF15846.5 OAG12126.1 - 0.05 13.4 0.1 0.073 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) Cupin_1 PF00190.22 OAG12128.1 - 1.2e-11 44.4 0.0 1.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Cupin DEAD PF00270.29 OAG12129.1 - 5.5e-42 143.5 0.2 8.1e-42 143.0 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG12129.1 - 1e-21 77.3 0.0 2.7e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG12129.1 - 3.2e-05 24.0 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG12129.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HATPase_c PF02518.26 OAG12130.1 - 1.4e-23 83.5 0.0 2.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG12130.1 - 2.4e-19 69.5 0.0 7.4e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG12130.1 - 1.9e-13 50.3 0.1 5.2e-13 48.8 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OAG12130.1 - 2.5e-06 28.2 0.0 1.4e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 OAG12130.1 - 3.5e-06 27.3 0.0 9.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 GAF domain CN_hydrolase PF00795.22 OAG12131.1 - 4.4e-36 124.6 0.0 6.1e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 OAG12131.1 - 4.6e-23 81.6 0.0 4.2e-22 78.4 0.0 2.2 1 1 0 1 1 1 1 NAD synthase MFS_1 PF07690.16 OAG12132.1 - 9.4e-35 120.2 28.1 1.5e-34 119.5 28.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NACHT PF05729.12 OAG12133.1 - 1.4e-07 31.6 0.1 5.1e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 OAG12133.1 - 0.00026 21.0 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAG12133.1 - 0.0019 18.5 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF1932 PF09130.11 OAG12133.1 - 0.0047 16.9 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) RsgA_GTPase PF03193.16 OAG12133.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 OAG12133.1 - 0.012 15.3 0.0 0.049 13.4 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OAG12133.1 - 0.012 14.8 0.3 0.27 10.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain DUF2791 PF10923.8 OAG12133.1 - 0.013 14.3 0.0 0.13 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) AAA_29 PF13555.6 OAG12133.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OAG12133.1 - 0.064 13.8 0.1 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 OAG12133.1 - 0.12 12.4 0.0 0.75 9.8 0.0 2.3 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_L30_N PF08079.12 OAG12134.1 - 4.3e-23 81.4 15.3 4.3e-23 81.4 15.3 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OAG12134.1 - 2e-18 66.0 2.5 2e-18 66.0 2.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e CSRNP_N PF16019.5 OAG12134.1 - 0.023 14.6 2.8 0.032 14.1 2.8 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Tipalpha PF16753.5 OAG12134.1 - 0.025 14.4 0.6 0.081 12.7 0.0 1.9 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter Methyltr_RsmB-F PF01189.17 OAG12135.1 - 7.9e-38 130.1 0.0 5.5e-27 94.7 0.0 4.2 3 1 0 4 4 4 3 16S rRNA methyltransferase RsmB/F DUF1871 PF08958.10 OAG12135.1 - 0.17 12.2 0.6 10 6.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) Herpes_LMP1 PF05297.11 OAG12136.1 - 2.1e-06 27.2 1.2 2.6e-06 26.9 1.2 1.0 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) DUF3328 PF11807.8 OAG12136.1 - 0.00011 22.0 1.7 0.051 13.3 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3328) YfhO PF09586.10 OAG12136.1 - 0.0007 18.0 0.7 0.00084 17.7 0.7 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF4383 PF14325.6 OAG12136.1 - 1.2 9.4 8.4 36 4.6 8.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) DUF2070 PF09843.9 OAG12136.1 - 2.7 6.2 12.6 3.5 5.8 12.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2569 PF10754.9 OAG12136.1 - 2.8 8.4 11.6 4.6 7.7 9.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Epimerase PF01370.21 OAG12137.1 - 1.9e-05 24.3 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG12137.1 - 0.062 12.5 0.0 0.3 10.2 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein UQ_con PF00179.26 OAG12139.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG12139.1 - 0.028 14.7 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 RWD domain MFS_1 PF07690.16 OAG12141.1 - 6.3e-36 124.0 27.7 1.8e-28 99.5 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG12141.1 - 5.7e-10 38.7 0.3 5.7e-10 38.7 0.3 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG12141.1 - 0.14 11.0 0.0 0.018 13.9 4.9 2.5 2 1 1 3 3 3 0 MFS_1 like family Fungal_trans PF04082.18 OAG12142.1 - 3.5e-25 88.5 0.0 8.9e-25 87.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG12142.1 - 8.9e-08 32.1 12.3 1.3e-07 31.6 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.23 OAG12143.1 - 1.2e-73 247.7 4.2 2e-73 246.9 4.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG12143.1 - 1.3e-44 150.8 0.5 2.6e-44 149.8 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG12143.1 - 0.044 13.6 0.8 9.3 6.2 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4350 PF14258.6 OAG12144.1 - 0.1 13.1 0.1 0.5 10.8 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) DUF2247 PF10004.9 OAG12145.1 - 0.021 14.6 0.7 0.037 13.8 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) DDRGK PF09756.9 OAG12145.1 - 0.033 13.8 4.2 3.5 7.2 4.5 2.4 2 0 0 2 2 2 0 DDRGK domain PPP4R2 PF09184.11 OAG12145.1 - 0.17 11.4 9.0 0.34 10.5 9.0 1.4 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 OAG12145.1 - 1.3 7.8 2.0 1.7 7.3 2.0 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 OAG12145.1 - 1.8 6.6 10.7 3.1 5.9 10.7 1.4 1 0 0 1 1 1 0 Nop14-like family NACHT PF05729.12 OAG12146.1 - 3.9e-25 88.7 0.0 7.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 OAG12146.1 - 2.1e-12 47.6 6.5 1.1e-10 42.0 0.1 3.3 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 OAG12146.1 - 0.0063 16.9 0.1 0.034 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 OAG12146.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAG12146.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4507 PF14964.6 OAG12147.1 - 0.0024 16.9 1.5 0.0027 16.7 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) HbrB PF08539.11 OAG12147.1 - 0.085 12.8 0.5 0.11 12.5 0.5 1.1 1 0 0 1 1 1 0 HbrB-like MFS_1 PF07690.16 OAG12149.1 - 5.1e-31 107.9 15.5 5.1e-31 107.9 15.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG12149.1 - 1.6e-05 24.0 31.1 0.00047 19.2 12.8 3.4 3 1 1 4 4 4 3 Sugar (and other) transporter TRI12 PF06609.13 OAG12149.1 - 0.0012 17.4 1.8 0.0012 17.4 1.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) RabGAP-TBC PF00566.18 OAG12150.1 - 4.4e-50 170.3 0.0 1.5e-49 168.6 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ZapB PF06005.12 OAG12150.1 - 0.012 16.0 6.0 0.012 16.0 6.0 4.8 4 2 0 4 4 4 0 Cell division protein ZapB Scaffolding_pro PF11418.8 OAG12150.1 - 1 10.0 5.9 15 6.2 0.1 3.5 3 1 0 3 3 3 0 Phi29 scaffolding protein Tup_N PF08581.10 OAG12150.1 - 3.5 8.0 15.3 4 7.8 0.8 3.6 3 0 0 3 3 3 0 Tup N-terminal Methyltransf_25 PF13649.6 OAG12152.1 - 1.9e-15 57.3 0.0 4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG12152.1 - 1.2e-13 51.5 0.0 2.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG12152.1 - 9.9e-11 41.6 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG12152.1 - 9.5e-10 38.6 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG12152.1 - 1.3e-09 38.7 0.0 3.3e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG12152.1 - 1.4e-06 27.9 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG12152.1 - 0.00017 21.1 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 OAG12152.1 - 0.0032 16.1 0.0 0.0043 15.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 OAG12152.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ribosomal_L6 PF00347.23 OAG12153.1 - 1.5e-19 70.4 0.0 8e-09 36.1 0.0 2.8 3 0 0 3 3 3 2 Ribosomal protein L6 Tht1 PF04163.12 OAG12154.1 - 6.4e-05 21.9 14.7 0.00024 20.0 11.0 2.8 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein Cytochrom_B562 PF07361.11 OAG12154.1 - 0.00024 21.7 3.4 0.00024 21.7 3.4 3.0 2 1 1 3 3 2 1 Cytochrome b562 TPR_MLP1_2 PF07926.12 OAG12154.1 - 0.00039 20.5 11.8 0.095 12.8 5.1 2.7 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OAG12154.1 - 0.0013 17.7 9.0 0.056 12.3 3.4 2.4 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF4407 PF14362.6 OAG12154.1 - 0.0025 17.2 1.3 0.005 16.2 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PP_kinase_N PF13089.6 OAG12154.1 - 0.003 17.8 0.6 0.003 17.8 0.6 2.8 1 1 1 2 2 2 1 Polyphosphate kinase N-terminal domain FA_FANCE PF11510.8 OAG12154.1 - 0.0036 16.7 0.3 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Fanconi Anaemia group E protein FANCE Baculo_PEP_C PF04513.12 OAG12154.1 - 0.007 16.4 8.9 0.35 10.9 0.3 2.7 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus EAP30 PF04157.16 OAG12154.1 - 0.016 14.5 10.8 0.065 12.5 10.2 2.2 1 1 0 1 1 1 0 EAP30/Vps36 family LPP PF04728.13 OAG12154.1 - 0.035 14.5 6.2 0.5 10.8 0.3 3.2 3 1 0 3 3 2 0 Lipoprotein leucine-zipper Apolipoprotein PF01442.18 OAG12154.1 - 0.037 13.9 11.2 0.34 10.8 11.1 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 OAG12154.1 - 0.048 13.9 2.3 7.9 6.8 0.3 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4870 PF09685.10 OAG12154.1 - 0.066 13.3 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) Mobilization_B PF17511.2 OAG12154.1 - 0.094 13.1 1.4 0.36 11.2 0.1 2.3 2 0 0 2 2 2 0 Mobilization protein B tRNA-synt_1d PF00750.19 OAG12154.1 - 0.16 10.9 5.6 0.064 12.2 1.4 2.1 1 1 1 2 2 2 0 tRNA synthetases class I (R) Mce4_CUP1 PF11887.8 OAG12154.1 - 0.17 11.3 1.8 0.42 10.0 0.7 2.2 1 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative HrpB7 PF09486.10 OAG12154.1 - 0.22 11.9 2.0 3.3 8.1 1.1 2.5 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CENP-H PF05837.12 OAG12154.1 - 0.22 11.9 10.9 1.5 9.3 0.8 2.8 3 0 0 3 3 2 0 Centromere protein H (CENP-H) DUF4094 PF13334.6 OAG12154.1 - 0.23 11.9 5.8 0.19 12.2 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) MIP-T3_C PF17749.1 OAG12154.1 - 0.24 11.4 9.1 0.12 12.3 2.6 2.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Fib_alpha PF08702.10 OAG12154.1 - 0.37 11.0 10.1 0.91 9.7 1.9 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 OAG12154.1 - 0.41 11.0 9.1 4.9 7.5 0.2 3.9 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MukF_M PF17192.4 OAG12154.1 - 0.66 9.7 5.5 0.31 10.8 1.4 2.4 1 1 0 2 2 2 0 MukF middle domain Laminin_II PF06009.12 OAG12154.1 - 0.76 9.8 6.5 7.3 6.6 0.5 2.7 2 0 0 2 2 2 0 Laminin Domain II FapA PF03961.13 OAG12154.1 - 1 7.9 10.5 1.3 7.5 2.2 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Prominin PF05478.11 OAG12154.1 - 1.5 6.6 15.8 0.68 7.8 6.2 2.1 1 1 1 2 2 2 0 Prominin DUF1664 PF07889.12 OAG12154.1 - 1.6 8.8 11.7 9.1 6.3 1.1 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) KELK PF15796.5 OAG12154.1 - 1.8 9.0 8.1 0.5 10.9 0.6 3.1 3 1 0 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LOH1CR12 PF10158.9 OAG12154.1 - 1.8 8.6 9.1 1.8 8.6 0.9 3.5 1 1 2 3 3 3 0 Tumour suppressor protein OmpH PF03938.14 OAG12154.1 - 3 8.2 13.9 0.44 10.9 2.6 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) YlqD PF11068.8 OAG12154.1 - 7 7.0 9.6 3.8 7.9 3.1 2.7 2 0 0 2 2 2 0 YlqD protein HIP1_clath_bdg PF16515.5 OAG12154.1 - 8.7 7.0 14.3 15 6.2 3.7 3.4 3 1 1 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_Mu_Gam PF07352.12 OAG12154.1 - 8.7 6.2 13.1 18 5.2 1.5 3.7 2 2 2 4 4 4 0 Bacteriophage Mu Gam like protein UQ_con PF00179.26 OAG12156.1 - 3.2e-37 127.3 0.1 4.2e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAG12156.1 - 0.029 14.2 0.1 0.053 13.4 0.1 1.4 1 1 0 1 1 1 0 UEV domain Astro_capsid_p PF12226.8 OAG12156.1 - 0.11 11.6 1.7 0.14 11.2 1.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 OAG12156.1 - 0.32 9.0 2.6 0.35 8.9 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pantoate_transf PF02548.15 OAG12157.1 - 3.4e-108 360.9 1.1 4.1e-108 360.7 1.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAG12157.1 - 3.4e-08 33.2 0.6 9e-08 31.9 0.1 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 OAG12157.1 - 0.041 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) APG12 PF04110.13 OAG12158.1 - 3.1e-22 78.8 0.0 3.8e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 OAG12158.1 - 0.0028 17.8 0.0 0.0033 17.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Dfp1_Him1_M PF08630.10 OAG12159.1 - 1.7e-38 131.7 0.2 1.7e-38 131.7 0.2 2.2 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 OAG12159.1 - 1.7e-20 72.8 0.1 3e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger HTH_DeoR PF08220.12 OAG12159.1 - 0.023 14.4 0.1 0.056 13.2 0.1 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain PTCB-BRCT PF12738.7 OAG12159.1 - 0.19 11.7 0.0 0.59 10.1 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain DUF3983 PF13137.6 OAG12159.1 - 0.47 10.3 4.1 1.4 8.8 4.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Octapeptide PF03373.14 OAG12159.1 - 7.7 7.4 5.8 27 5.7 0.3 2.8 2 0 0 2 2 2 0 Octapeptide repeat zf-RING_2 PF13639.6 OAG12162.1 - 1.7e-09 37.9 2.7 2.5e-09 37.3 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG12162.1 - 2.3e-06 27.8 4.5 2e-05 24.8 4.6 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG12162.1 - 0.00013 21.9 0.5 0.00021 21.3 0.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAG12162.1 - 0.00083 19.0 1.4 0.0013 18.4 1.4 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG12162.1 - 0.001 18.9 5.1 0.003 17.4 4.7 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG12162.1 - 0.0033 17.4 6.1 0.0057 16.7 6.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG12162.1 - 0.0058 16.5 1.6 0.0097 15.8 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG12162.1 - 0.15 12.0 0.9 0.45 10.4 0.8 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.18 OAG12163.1 - 2.8e-05 23.3 0.1 5.2e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trp_halogenase PF04820.14 OAG12165.1 - 4.3e-28 98.4 0.1 1.2e-13 50.7 0.0 2.3 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 OAG12165.1 - 2.5e-12 46.7 0.0 6.3e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OAG12165.1 - 3.1e-05 23.2 0.0 5.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG12165.1 - 3.2e-05 23.5 0.5 4.7e-05 22.9 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG12165.1 - 4.1e-05 23.0 0.0 7.1e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG12165.1 - 0.00018 20.7 0.1 0.00032 19.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG12165.1 - 0.00026 19.8 0.0 0.00089 18.1 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG12165.1 - 0.00038 20.6 0.1 0.00038 20.6 0.1 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG12165.1 - 0.0086 15.7 0.1 0.028 14.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG12165.1 - 0.059 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG12165.1 - 0.21 10.8 0.7 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family ABC2_membrane PF01061.24 OAG12166.1 - 2.9e-27 95.5 10.4 3.2e-27 95.3 10.4 1.0 1 0 0 1 1 1 1 ABC-2 type transporter CRISPR_Cse1 PF09481.10 OAG12166.1 - 0.28 10.2 0.0 0.35 9.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) ABC2_membrane PF01061.24 OAG12167.1 - 1.3e-38 132.6 23.5 1.6e-38 132.3 23.5 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OAG12167.1 - 0.00034 19.8 11.1 0.00051 19.2 11.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3188 PF11384.8 OAG12167.1 - 0.04 13.6 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) PEPCK_ATP PF01293.20 OAG12168.1 - 4.3e-217 721.3 0.0 5e-217 721.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 OAG12168.1 - 0.12 12.5 0.1 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG12168.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain zf-C3HC PF07967.13 OAG12169.1 - 1.5e-39 135.0 0.2 2.6e-30 105.2 0.1 2.5 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 OAG12169.1 - 6.7e-22 77.5 0.3 6.7e-22 77.5 0.3 2.6 3 0 0 3 3 3 1 Rsm1-like Inositol_P PF00459.25 OAG12170.1 - 6.3e-55 186.6 0.9 3.8e-54 184.0 0.9 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Drf_DAD PF06345.11 OAG12170.1 - 0.073 13.1 0.4 0.19 11.8 0.4 1.7 1 0 0 1 1 1 0 DRF Autoregulatory Domain DUF747 PF05346.11 OAG12172.1 - 3.4e-123 411.2 4.6 4.3e-123 410.8 4.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family COesterase PF00135.28 OAG12173.1 - 3.5e-80 270.3 0.0 7e-72 242.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG12173.1 - 6.5e-10 39.2 0.1 1e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG12173.1 - 0.022 14.3 0.4 0.036 13.5 0.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Transglut_i_TM PF14400.6 OAG12174.1 - 0.00031 20.8 0.0 0.00067 19.8 0.1 1.5 2 0 0 2 2 2 1 Inactive transglutaminase fused to 7 transmembrane helices SapB_1 PF05184.15 OAG12174.1 - 0.082 12.9 0.6 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 Saposin-like type B, region 1 AAA_12 PF13087.6 OAG12175.1 - 3.3e-35 121.5 0.0 6.6e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG12175.1 - 2.3e-19 70.2 2.0 3.5e-13 49.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 OAG12175.1 - 1.1e-09 38.8 0.0 2.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG12175.1 - 7.3e-06 25.8 0.0 2.2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 OAG12175.1 - 2.1e-05 24.2 0.0 9.9e-05 22.0 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 OAG12175.1 - 0.00083 19.3 0.0 0.0043 16.9 0.0 2.2 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 OAG12175.1 - 0.00088 19.1 0.0 2.9 7.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAG12175.1 - 0.00096 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Herpes_Helicase PF02689.14 OAG12175.1 - 0.013 13.4 0.0 0.019 12.9 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA PF00004.29 OAG12175.1 - 0.043 14.3 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG12175.1 - 0.047 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAG12175.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 OAG12175.1 - 0.05 14.0 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 OAG12175.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 OAG12175.1 - 0.079 12.8 0.2 1.6 8.7 0.1 2.9 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain zf-PHD-like PF15446.6 OAG12176.1 - 8.6e-68 227.2 12.0 2.2e-67 225.9 12.0 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 OAG12176.1 - 1.4e-56 191.7 0.0 2.1e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 OAG12176.1 - 2.4e-27 94.6 0.5 6e-27 93.3 0.5 1.8 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 OAG12176.1 - 1.6e-19 70.3 0.0 4.4e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG12176.1 - 2.8e-09 37.2 0.0 5.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAG12176.1 - 1.5e-08 34.2 0.4 3.7e-08 32.9 0.4 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1087 PF06465.13 OAG12176.1 - 5.2e-05 23.2 0.0 0.00019 21.4 0.0 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) PHD PF00628.29 OAG12176.1 - 5.6e-05 22.9 3.5 5.6e-05 22.9 3.5 3.8 4 1 0 4 4 3 1 PHD-finger Chromo PF00385.24 OAG12176.1 - 9.5e-05 22.2 1.7 0.064 13.2 0.3 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 OAG12176.1 - 0.00045 20.0 0.0 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Tudor_3 PF18115.1 OAG12176.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Zf_RING PF16744.5 OAG12176.1 - 0.45 10.7 12.4 3.2 8.0 0.9 2.9 2 1 0 2 2 2 0 KIAA1045 RING finger PHD_2 PF13831.6 OAG12176.1 - 0.58 9.8 17.4 0.01 15.4 4.8 3.6 3 1 0 3 3 3 0 PHD-finger zinc_ribbon_4 PF13717.6 OAG12176.1 - 2.5 8.1 13.6 4 7.4 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.22 OAG12176.1 - 5.2 7.0 15.5 0.2 11.5 1.3 3.9 4 0 0 4 4 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 OAG12176.1 - 9 6.5 9.4 45 4.4 9.4 2.3 1 0 0 1 1 1 0 AT hook motif SpoU_methylase PF00588.19 OAG12177.1 - 7.7e-22 78.0 0.0 4.1e-21 75.6 0.0 2.1 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OAG12177.1 - 1.2e-08 35.1 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding VD10_N PF08476.10 OAG12177.1 - 0.05 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral D10 N-terminal Zn_clus PF00172.18 OAG12181.1 - 5.8e-07 29.5 9.3 1.2e-06 28.5 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG12181.1 - 0.00076 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PLA2_B PF01735.18 OAG12182.1 - 3.9e-193 642.3 4.6 4.6e-193 642.1 4.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 OAG12182.1 - 0.37 11.1 2.1 0.7 10.2 2.1 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain RCC1 PF00415.18 OAG12183.1 - 2.5e-23 82.4 0.8 1.7e-07 31.8 0.0 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG12183.1 - 3.4e-13 49.0 3.7 8.3e-08 31.8 0.1 4.2 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OAG12183.1 - 3e-10 40.3 0.1 1.1e-05 25.6 0.0 3.1 2 1 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 OAG12183.1 - 3e-09 37.2 0.2 1.3e-08 35.2 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG12183.1 - 1.9e-07 31.6 0.1 4.2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG12183.1 - 8.2e-05 22.7 0.3 1.4 9.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG12183.1 - 0.0046 17.2 0.1 0.34 11.3 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG12183.1 - 0.012 16.0 0.5 1.6 9.3 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat ATG13 PF10033.9 OAG12185.1 - 7.9e-66 222.2 0.0 1.3e-65 221.4 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 adh_short_C2 PF13561.6 OAG12186.1 - 1.4e-48 165.5 0.0 1.7e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG12186.1 - 5.8e-37 127.1 0.1 8.6e-37 126.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG12186.1 - 2.9e-10 40.3 0.3 3.8e-10 40.0 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG12186.1 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Diphthamide_syn PF01866.17 OAG12187.1 - 7e-85 285.1 0.0 1e-84 284.5 0.0 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ARID PF01388.21 OAG12189.1 - 5.4e-19 68.6 0.1 1.9e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF4196 PF13846.6 OAG12191.1 - 0.99 9.6 12.5 2.3 8.4 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4196) GREB1 PF15782.5 OAG12191.1 - 4.1 4.4 4.7 8.8 3.3 4.7 1.4 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rad4 PF03835.15 OAG12192.1 - 7.9e-38 129.4 3.6 5.6e-37 126.7 2.9 2.2 1 1 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAG12192.1 - 3.5e-27 94.6 0.1 6.5e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAG12192.1 - 3.5e-20 71.6 0.4 7.8e-20 70.5 0.4 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OAG12192.1 - 3.7e-17 63.0 0.1 1.9e-16 60.8 0.1 2.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 OAG12192.1 - 0.0079 16.6 0.1 0.053 14.0 0.0 2.3 2 1 0 2 2 2 1 Transglutaminase-like superfamily HMA PF00403.26 OAG12193.1 - 0.00012 22.5 0.1 0.00019 21.8 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 OAG12194.1 - 2.5e-42 144.4 1.6 2.5e-42 144.4 1.6 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG12194.1 - 2.6e-24 86.7 0.2 5.3e-24 85.7 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG12194.1 - 7.3e-06 25.9 0.4 0.00074 19.3 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1980 PF09323.10 OAG12194.1 - 0.027 14.4 0.1 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) HAD PF12710.7 OAG12194.1 - 0.051 14.0 0.6 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1996 PF09362.10 OAG12196.1 - 1.7e-75 254.1 4.1 2.1e-75 253.7 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1349 PF07081.11 OAG12197.1 - 2.8e-16 59.8 0.0 3.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Complex1_30kDa PF00329.19 OAG12198.1 - 4.2e-45 153.3 0.0 5.8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 OAG12199.1 - 3e-20 71.7 12.2 5.3e-20 70.9 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 OAG12199.1 - 6.8e-07 29.0 0.0 2.2e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 OAG12199.1 - 1.3e-06 28.1 10.8 2.8e-06 27.1 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 OAG12199.1 - 0.0045 16.4 2.9 0.0045 16.4 2.9 3.5 3 1 0 3 3 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 OAG12199.1 - 0.0045 17.3 13.3 0.0082 16.5 13.3 1.4 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 OAG12199.1 - 0.005 16.8 6.2 0.0093 15.9 6.2 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 OAG12199.1 - 0.0058 16.7 6.4 0.014 15.5 6.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_4 PF14447.6 OAG12199.1 - 0.0086 15.9 10.2 0.05 13.5 7.9 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAG12199.1 - 0.1 12.5 10.3 0.21 11.5 10.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OAG12199.1 - 0.53 10.4 7.6 1.3 9.2 7.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 OAG12199.1 - 0.57 10.3 7.0 0.9 9.6 5.7 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 OAG12199.1 - 1.5 8.8 13.4 3 7.9 13.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FYVE_2 PF02318.16 OAG12199.1 - 3.5 7.9 13.0 0.15 12.3 6.1 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger FYDLN_acid PF09538.10 OAG12199.1 - 7.8 7.2 17.4 0.35 11.6 0.3 3.9 4 0 0 4 4 3 0 Protein of unknown function (FYDLN_acid) DUF3138 PF11336.8 OAG12200.1 - 1.9 7.0 8.3 3.2 6.2 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) zf-CCCH_4 PF18044.1 OAG12201.1 - 1.2e-07 31.4 5.0 1.2e-07 31.4 5.0 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAG12201.1 - 2.6e-06 27.2 4.6 2.6e-06 27.2 4.6 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG12201.1 - 5.6e-05 23.0 9.0 5.6e-05 23.0 9.0 3.2 4 0 0 4 4 4 1 Zinc finger domain Torus PF16131.5 OAG12201.1 - 0.00034 21.3 0.2 0.0011 19.6 0.2 1.9 1 0 0 1 1 1 1 Torus domain NTP_transferase PF00483.23 OAG12201.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase DIOX_N PF14226.6 OAG12202.1 - 4e-32 111.4 0.0 5.8e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG12202.1 - 2.2e-19 69.8 0.0 9.1e-19 67.8 0.0 1.9 1 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NTP_transferase PF00483.23 OAG12203.1 - 2.3e-32 112.5 0.0 3e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OAG12203.1 - 1.1e-09 37.6 8.5 5.1e-07 29.2 0.2 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAG12203.1 - 1.6e-09 38.3 0.0 2.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OAG12203.1 - 0.027 14.2 2.8 0.076 12.8 0.3 2.6 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 OAG12203.1 - 0.049 13.4 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 OAG12203.1 - 0.15 10.1 0.1 0.56 8.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) Ubie_methyltran PF01209.18 OAG12204.1 - 5.2e-81 271.4 0.0 6.3e-81 271.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAG12204.1 - 8.5e-17 61.6 0.0 1.9e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG12204.1 - 1.8e-14 54.2 0.0 5.1e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG12204.1 - 2.8e-13 49.9 0.0 3.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG12204.1 - 3.1e-10 40.7 0.0 5.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG12204.1 - 8.6e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OAG12204.1 - 0.025 14.4 0.0 0.069 13.0 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase E1_dh PF00676.20 OAG12205.1 - 4e-91 305.1 0.0 5e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 OAG12205.1 - 0.0032 17.3 0.1 0.024 14.4 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 OAG12205.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Abhydrolase_6 PF12697.7 OAG12206.1 - 1.7e-11 45.1 0.5 2.5e-11 44.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG12206.1 - 3.7e-05 23.5 0.0 0.00022 21.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG12206.1 - 7.1e-05 22.2 0.0 0.00093 18.5 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Fungal_trans_2 PF11951.8 OAG12207.1 - 1.6e-08 33.7 0.6 2.3e-08 33.3 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3987 PF13148.6 OAG12207.1 - 0.014 14.4 0.1 0.025 13.6 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF2239 PF09998.9 OAG12207.1 - 0.072 12.9 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) MAP17 PF15807.5 OAG12207.1 - 0.42 10.8 1.9 0.8 9.9 1.9 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SNF2_N PF00176.23 OAG12208.1 - 8.2e-63 212.2 0.0 4.2e-61 206.6 0.0 3.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG12208.1 - 1e-16 61.2 0.0 8.3e-16 58.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3425 PF11905.8 OAG12208.1 - 2.1e-11 43.8 1.5 8.3e-11 41.9 1.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) ResIII PF04851.15 OAG12208.1 - 2.4e-05 24.4 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG12208.1 - 0.00056 19.7 0.1 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4267 PF14087.6 OAG12209.1 - 0.00096 19.2 0.4 0.0013 18.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) ATG22 PF11700.8 OAG12210.1 - 1.2e-136 456.1 23.3 1.4e-136 455.9 23.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAG12210.1 - 1.5e-13 50.5 27.4 3e-09 36.3 5.6 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Cadherin_C_2 PF16492.5 OAG12210.1 - 0.087 13.6 0.0 0.28 12.0 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Lipase_GDSL_2 PF13472.6 OAG12211.1 - 2.7e-07 31.2 0.1 4.3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG12211.1 - 9.4e-07 29.0 0.1 1.1e-06 28.8 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_43 PF04616.14 OAG12212.1 - 1e-65 221.9 1.0 1.3e-65 221.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG12212.1 - 1e-16 61.3 0.0 1.7e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Rb_C PF08934.10 OAG12212.1 - 0.21 11.4 0.1 0.35 10.7 0.1 1.2 1 0 0 1 1 1 0 Rb C-terminal domain Oxysterol_BP PF01237.18 OAG12213.1 - 9.7e-115 383.3 0.1 4.1e-114 381.3 0.1 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 OAG12213.1 - 1.6e-38 130.8 3.0 3.2e-38 129.9 0.1 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 OAG12213.1 - 2.7e-05 24.6 0.0 7.5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Plus-3 PF03126.18 OAG12214.1 - 2.1e-25 89.4 0.0 4.4e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.13 OAG12215.1 - 2.8e-69 232.3 1.0 3.4e-69 232.0 0.5 1.4 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 OAG12215.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Rubrerythrin MRC1 PF09444.10 OAG12216.1 - 3.4e-32 112.0 19.4 3.4e-32 112.0 19.4 9.1 7 2 3 10 10 10 1 MRC1-like domain MOSC PF03473.17 OAG12218.1 - 4.2e-30 104.4 0.0 7e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG12218.1 - 3.4e-15 56.0 0.0 5.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain FAD_binding_4 PF01565.23 OAG12219.1 - 1.5e-24 86.4 0.3 2.5e-24 85.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG12219.1 - 0.00034 20.7 1.4 0.00067 19.7 1.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like VPS13_mid_rpt PF16910.5 OAG12221.1 - 1.1e-100 335.9 12.0 3.5e-96 321.2 0.8 5.4 4 1 1 5 5 5 3 Repeating coiled region of VPS13 SHR-BD PF06650.12 OAG12221.1 - 7.3e-95 317.4 0.0 2.4e-94 315.7 0.0 2.0 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 OAG12221.1 - 4.2e-85 285.3 0.3 1e-81 274.2 0.0 4.4 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 OAG12221.1 - 2.3e-72 242.5 3.7 1.7e-68 229.9 0.3 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OAG12221.1 - 3.3e-42 143.3 0.9 1.5e-41 141.1 0.1 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OAG12221.1 - 8.8e-05 22.8 0.0 0.00032 21.0 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF896 PF05979.12 OAG12221.1 - 2.1 8.2 7.0 28 4.7 2.6 3.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF3128 PF11326.8 OAG12222.1 - 1.6e-25 89.3 2.4 2.2e-25 88.8 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) HSP70 PF00012.20 OAG12223.1 - 7.7e-260 863.2 7.1 8.8e-260 863.0 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG12223.1 - 5.2e-17 61.6 0.0 4.6e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAG12223.1 - 0.0013 18.5 0.0 0.0049 16.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 OAG12223.1 - 0.014 14.7 0.1 0.03 13.6 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 OAG12223.1 - 0.017 15.5 4.0 6.1 7.3 0.2 3.5 3 2 0 3 3 3 0 Cell division protein FtsA DUF3429 PF11911.8 OAG12225.1 - 1.3e-44 152.0 14.4 1.7e-44 151.6 14.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.16 OAG12226.1 - 5.4e-74 248.2 0.5 8.1e-74 247.6 0.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG12226.1 - 2.4e-66 223.8 0.0 3.2e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain zf-C3H2C3 PF17122.5 OAG12228.1 - 5.6 7.1 9.4 0.4 10.8 3.6 2.2 2 2 1 3 3 3 0 Zinc-finger adh_short PF00106.25 OAG12229.1 - 7.5e-05 22.3 0.0 1.1 8.6 0.0 3.3 2 1 1 3 3 3 3 short chain dehydrogenase Shugoshin_N PF07558.11 OAG12231.1 - 0.00049 19.9 6.0 0.00058 19.7 0.1 2.9 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 OAG12231.1 - 0.023 13.6 19.3 0.043 12.7 19.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 OAG12231.1 - 0.15 11.8 26.7 0.14 12.0 23.5 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2730 PF10805.8 OAG12231.1 - 0.29 11.2 3.9 0.39 10.8 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF3450 PF11932.8 OAG12231.1 - 0.78 9.0 23.6 0.079 12.3 18.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) TMCO5 PF14992.6 OAG12231.1 - 0.79 9.2 11.1 2 7.9 11.1 1.7 1 0 0 1 1 1 0 TMCO5 family BLOC1_2 PF10046.9 OAG12231.1 - 1.9 8.8 14.4 0.21 11.9 4.2 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dor1 PF04124.12 OAG12231.1 - 2.5 6.7 10.5 0.42 9.3 5.7 1.9 2 0 0 2 2 2 0 Dor1-like family Cnn_1N PF07989.11 OAG12231.1 - 4.1 7.6 21.8 0.063 13.4 10.0 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Myc-LZ PF02344.15 OAG12231.1 - 5.3 7.2 8.1 0.32 11.1 2.3 2.0 2 0 0 2 2 2 0 Myc leucine zipper domain KASH_CCD PF14662.6 OAG12231.1 - 6.4 6.6 23.1 24 4.7 16.8 3.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4665 PF15679.5 OAG12231.1 - 7.1 7.3 8.2 5.4 7.7 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) FapA PF03961.13 OAG12231.1 - 7.6 5.0 10.7 4.5 5.8 7.4 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A Phlebovirus_NSM PF07246.11 OAG12231.1 - 8.3 5.7 8.6 6.8 6.0 6.5 1.8 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Rhomboid PF01694.22 OAG12232.1 - 0.0065 16.5 0.9 0.0065 16.5 0.9 2.0 2 1 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 OAG12232.1 - 0.011 16.3 1.4 0.011 16.3 1.4 1.7 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Gly-zipper_Omp PF13488.6 OAG12232.1 - 0.052 13.5 0.4 0.052 13.5 0.4 3.2 3 0 0 3 3 3 0 Glycine zipper MF_alpha_N PF05436.11 OAG12233.1 - 0.053 13.4 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF3328 PF11807.8 OAG12234.1 - 4.3e-51 173.8 0.0 5.1e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MRP-S26 PF14943.6 OAG12237.1 - 0.047 13.6 1.9 0.082 12.8 1.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 HORMA PF02301.18 OAG12238.1 - 2.3e-41 141.7 0.0 4.2e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 OAG12238.1 - 0.00059 19.7 8.1 0.0012 18.7 8.1 1.4 1 0 0 1 1 1 1 PHD-finger WD40 PF00400.32 OAG12240.1 - 1.1e-39 133.7 18.3 9.1e-05 23.2 0.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 OAG12240.1 - 1.8e-09 37.4 0.2 3.7e-09 36.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 OAG12240.1 - 3.1e-09 37.0 1.2 0.71 10.2 0.0 6.3 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 OAG12240.1 - 1.6e-08 34.2 0.3 3.7e-08 33.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAG12240.1 - 0.0011 17.7 4.4 6.9 5.2 0.1 4.8 3 2 2 6 6 6 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 OAG12240.1 - 0.0015 18.4 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 F-box PQQ_2 PF13360.6 OAG12240.1 - 0.019 14.6 1.3 1.7 8.1 1.0 3.0 1 1 0 1 1 1 0 PQQ-like domain BRAP2 PF07576.12 OAG12241.1 - 1.5e-34 118.2 0.0 2.6e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 OAG12241.1 - 3e-19 69.1 5.5 7.7e-19 67.8 5.5 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 OAG12241.1 - 2.9e-08 33.9 8.8 2.9e-08 33.9 8.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG12241.1 - 6.4e-06 25.9 8.2 6.4e-06 25.9 8.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG12241.1 - 6.2e-05 22.8 7.3 6.2e-05 22.8 7.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG12241.1 - 9.5e-05 22.4 4.3 0.00041 20.3 4.3 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG12241.1 - 0.00018 21.7 6.0 0.00054 20.2 6.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAG12241.1 - 0.00037 20.2 4.9 0.00037 20.2 4.9 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OAG12241.1 - 0.00074 19.3 15.6 0.00088 19.1 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG12241.1 - 0.0027 17.7 6.5 0.0027 17.7 6.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 OAG12241.1 - 0.0027 17.5 3.0 0.0072 16.2 3.0 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OAG12241.1 - 0.013 15.6 4.4 0.036 14.1 4.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tropomyosin PF00261.20 OAG12241.1 - 0.017 14.5 18.3 0.025 14.0 18.3 1.2 1 0 0 1 1 1 0 Tropomyosin NBD94 PF16830.5 OAG12241.1 - 0.18 12.2 1.5 4.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH Shugoshin_N PF07558.11 OAG12241.1 - 0.25 11.2 1.0 0.55 10.1 1.0 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Fib_alpha PF08702.10 OAG12241.1 - 0.34 11.1 6.8 9.1 6.5 4.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 OAG12241.1 - 0.42 9.2 11.8 0.61 8.7 11.8 1.1 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 OAG12241.1 - 0.53 10.5 19.7 13 5.9 19.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OAG12241.1 - 0.9 9.6 24.0 1.6 8.8 24.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prok-RING_4 PF14447.6 OAG12241.1 - 0.96 9.4 18.6 0.24 11.3 8.9 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 YabA PF06156.13 OAG12241.1 - 1.3 9.7 7.4 6.8 7.4 4.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Zn_ribbon_17 PF17120.5 OAG12241.1 - 1.4 8.6 13.3 0.09 12.4 5.4 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF1993 PF09351.10 OAG12241.1 - 2.2 8.4 9.6 0.74 9.9 5.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Nsp1_C PF05064.13 OAG12241.1 - 2.7 7.8 7.6 3 7.7 3.5 2.6 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF4407 PF14362.6 OAG12241.1 - 3 7.1 17.0 4.6 6.5 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 OAG12241.1 - 4.7 7.3 18.1 0.36 10.9 1.9 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 OAG12241.1 - 6.8 5.9 19.3 0.48 9.7 11.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 OAG12241.1 - 7.7 6.6 16.6 4.9 7.2 10.2 2.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 OAG12241.1 - 9.1 6.7 18.4 23 5.4 6.2 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 OAG12241.1 - 9.9 6.2 7.9 19 5.3 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RasGAP PF00616.19 OAG12242.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Drf_GBD PF06371.13 OAG12243.1 - 4.6e-21 75.2 0.0 1.4e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Mannosyl_trans2 PF04188.13 OAG12245.1 - 5e-56 190.9 7.1 6.2e-56 190.6 7.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Ribosomal_L7Ae PF01248.26 OAG12246.1 - 4.7e-22 77.5 0.4 7.6e-22 76.9 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 OAG12246.1 - 0.15 11.1 0.3 0.19 10.7 0.3 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) OCD_Mu_crystall PF02423.15 OAG12247.1 - 1.4e-10 40.6 1.0 2.8e-07 29.8 0.1 3.9 2 1 1 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAG12247.1 - 0.002 18.2 0.0 0.027 14.5 0.0 2.3 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase BLM10_mid PF16507.5 OAG12248.1 - 1.5e-202 673.9 0.0 7.3e-202 671.7 0.0 2.0 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAG12248.1 - 2.1e-28 98.1 0.0 2.2e-27 94.8 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 OAG12248.1 - 1.3e-23 83.1 0.0 4.2e-23 81.4 0.0 2.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 OAG12248.1 - 0.021 15.0 0.1 17 6.0 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat FRP PF18032.1 OAG12248.1 - 0.027 15.1 0.2 2.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Photoprotection regulator fluorescence recovery protein IFRD PF05004.13 OAG12248.1 - 0.033 13.3 0.1 0.37 9.8 0.0 2.3 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) AP_endonuc_2_N PF07582.12 OAG12248.1 - 0.033 13.9 0.0 0.15 11.8 0.0 2.1 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus Sld5 PF05916.11 OAG12249.1 - 4e-20 72.3 0.0 6.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Prenyltransf PF01255.19 OAG12251.1 - 4.2e-83 278.3 0.2 8.8e-83 277.2 0.2 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3446 PF11928.8 OAG12251.1 - 0.36 11.2 6.2 0.63 10.4 6.2 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain Nrap_D5 PF17406.2 OAG12252.1 - 0.074 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Glyco_transf_25 PF01755.17 OAG12253.1 - 2.6e-09 37.2 0.0 9.6e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Peptidase_S10 PF00450.22 OAG12254.1 - 2.1e-79 267.9 0.0 2.9e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase SET PF00856.28 OAG12257.1 - 8.1e-09 36.1 0.0 2.4e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 SET domain DUF3857 PF12969.7 OAG12257.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Pkinase PF00069.25 OAG12258.1 - 0.00015 21.3 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12258.1 - 0.039 13.2 0.0 1.7 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Cyclin_N PF00134.23 OAG12260.1 - 5.6e-14 52.0 0.1 1.5e-13 50.6 0.0 1.7 2 1 1 3 3 3 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAG12260.1 - 7.1e-08 33.0 0.0 1.9e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin UL73_N PF12522.8 OAG12261.1 - 0.52 10.1 3.3 1.2 9.0 3.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Pkinase PF00069.25 OAG12262.1 - 1.7e-41 142.4 0.0 4.3e-41 141.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12262.1 - 7.6e-28 97.5 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG12262.1 - 0.00043 19.7 0.0 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAG12262.1 - 0.015 15.2 1.5 2 8.3 0.1 3.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG12262.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldose_epim PF01263.20 OAG12264.1 - 5.2e-42 144.2 0.0 6.1e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.8 OAG12265.1 - 1.9e-102 343.1 1.1 3.7e-102 342.1 1.1 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Sec7_N PF12783.7 OAG12265.1 - 0.011 15.7 0.3 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Ric8 PF10165.9 OAG12266.1 - 3.7e-129 431.8 1.0 4.2e-129 431.6 1.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Zn_clus PF00172.18 OAG12268.1 - 3.8e-07 30.1 5.2 8.2e-07 29.0 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG12268.1 - 0.00056 18.8 0.1 0.0011 17.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C48 PF02902.19 OAG12269.1 - 0.00018 21.4 0.1 0.00048 20.0 0.1 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 OAG12269.1 - 0.038 13.7 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease Cu-oxidase_3 PF07732.15 OAG12272.1 - 4e-44 149.4 3.5 8.6e-41 138.7 0.2 3.6 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG12272.1 - 7.3e-43 145.6 5.0 8.2e-41 138.9 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG12272.1 - 3.2e-34 118.3 0.2 1.2e-33 116.5 0.2 2.0 1 0 0 1 1 1 1 Multicopper oxidase RTA1 PF04479.13 OAG12274.1 - 1.5e-39 135.7 4.2 2.7e-39 134.9 4.2 1.4 1 0 0 1 1 1 1 RTA1 like protein DUF996 PF06195.13 OAG12274.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF996) Fungal_trans_2 PF11951.8 OAG12275.1 - 0.014 14.2 0.1 0.047 12.5 0.0 1.6 1 1 0 2 2 2 0 Fungal specific transcription factor domain MCU PF04678.13 OAG12276.1 - 2.9e-25 89.4 0.1 2.9e-25 89.4 0.1 2.1 3 0 0 3 3 3 1 Mitochondrial calcium uniporter Pectate_lyase PF03211.13 OAG12277.1 - 2.1e-81 272.4 7.0 2.5e-81 272.1 7.0 1.1 1 0 0 1 1 1 1 Pectate lyase DHBP_synthase PF00926.19 OAG12278.1 - 4.7e-78 261.1 0.0 5.9e-78 260.8 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Xan_ur_permease PF00860.20 OAG12279.1 - 1.4e-23 83.2 32.2 3.2e-22 78.8 30.1 2.5 2 1 0 2 2 2 1 Permease family Exo_endo_phos PF03372.23 OAG12279.1 - 0.039 13.5 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF543 PF04418.12 OAG12279.1 - 6.9 6.7 6.5 70 3.5 1.5 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF543) MFS_MOT1 PF16983.5 OAG12279.1 - 9.2 6.7 20.1 0.17 12.3 4.7 3.4 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Draxin PF15550.6 OAG12283.1 - 0.72 9.7 4.0 0.23 11.3 0.5 1.9 2 0 0 2 2 2 0 Draxin RRM_1 PF00076.22 OAG12284.1 - 5.6e-81 266.4 5.0 6.9e-20 70.7 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAG12284.1 - 1.3e-27 95.7 0.7 1.3e-27 95.7 0.7 2.9 3 1 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 OAG12284.1 - 2.4e-12 46.5 2.0 0.0039 16.8 0.0 5.1 2 1 2 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG12284.1 - 3.8e-05 23.5 0.2 0.0048 16.7 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAG12284.1 - 0.00048 20.2 1.0 5.5 7.2 0.0 5.2 4 2 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OAG12284.1 - 0.015 15.3 0.3 37 4.4 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 OAG12284.1 - 0.075 12.7 2.6 17 5.2 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain CbiG_mid PF11761.8 OAG12284.1 - 0.14 12.3 0.8 22 5.3 0.0 3.0 3 1 0 3 3 3 0 Cobalamin biosynthesis central region FBPase PF00316.20 OAG12285.1 - 8.2e-69 230.9 0.1 1.1e-68 230.5 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Transket_pyr PF02779.24 OAG12286.1 - 1.2e-61 207.5 0.0 2.1e-61 206.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 OAG12286.1 - 8.4e-59 197.6 0.0 1.3e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 OAG12286.1 - 2.6e-55 187.5 0.0 3.5e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 OAG12286.1 - 8.6e-19 66.9 1.6 1.6e-18 66.0 1.6 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus NMT1 PF09084.11 OAG12286.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like HEAT_2 PF13646.6 OAG12287.1 - 6.3e-07 29.7 1.6 0.042 14.3 0.0 4.6 4 2 1 5 5 5 1 HEAT repeats CLASP_N PF12348.8 OAG12287.1 - 4.3e-06 26.4 0.1 0.00015 21.4 0.1 2.3 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 OAG12287.1 - 1e-05 25.7 0.1 0.022 14.8 0.1 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG12287.1 - 1.2e-05 25.1 1.1 5.6 7.5 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Adaptin_N PF01602.20 OAG12287.1 - 0.00012 20.8 1.3 0.0012 17.5 1.3 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Arm PF00514.23 OAG12287.1 - 0.022 14.8 0.4 12 6.1 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TAN PF11640.8 OAG12287.1 - 0.024 14.8 0.7 0.12 12.5 0.7 2.3 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 OAG12287.1 - 0.025 14.2 0.4 0.96 9.0 0.1 3.0 2 2 2 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II HALZ PF02183.18 OAG12287.1 - 0.055 13.7 11.0 0.026 14.7 2.8 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1394 PF07159.12 OAG12287.1 - 0.069 12.4 2.3 5.2 6.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1394) HEAT_EZ PF13513.6 OAG12287.1 - 0.092 13.3 2.2 2.6 8.6 0.0 4.3 5 0 0 5 5 4 0 HEAT-like repeat p25-alpha PF05517.12 OAG12287.1 - 0.11 12.6 0.3 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 p25-alpha Dor1 PF04124.12 OAG12287.1 - 0.16 10.6 3.7 0.39 9.4 3.7 1.6 1 0 0 1 1 1 0 Dor1-like family Macoilin PF09726.9 OAG12287.1 - 0.22 10.0 3.3 0.4 9.2 3.3 1.3 1 0 0 1 1 1 0 Macoilin family Atg14 PF10186.9 OAG12287.1 - 0.34 10.0 9.1 0.77 8.8 9.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MctB PF11382.8 OAG12287.1 - 0.37 10.5 6.1 0.1 12.3 1.4 2.3 3 0 0 3 3 2 0 Copper transport outer membrane protein, MctB ImpA_N PF06812.12 OAG12287.1 - 0.43 10.7 3.0 0.48 10.5 0.7 2.4 3 0 0 3 3 2 0 ImpA, N-terminal, type VI secretion system TPR_MLP1_2 PF07926.12 OAG12287.1 - 0.82 9.7 14.0 4.6 7.3 14.0 2.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 OAG12287.1 - 0.85 9.5 3.9 0.67 9.9 0.7 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 OAG12287.1 - 1.3 8.8 14.5 0.42 10.4 5.3 2.8 1 1 1 2 2 2 0 Septum formation initiator KASH_CCD PF14662.6 OAG12287.1 - 4.2 7.2 15.8 0.47 10.3 10.8 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.5 OAG12287.1 - 6.3 7.1 8.5 0.86 9.8 3.5 2.2 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II TMF_DNA_bd PF12329.8 OAG12287.1 - 9.7 6.3 11.7 2.4 8.2 5.1 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.32 OAG12288.1 - 1.4e-52 174.5 26.6 1.4e-08 35.2 0.5 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG12288.1 - 1.4e-13 50.9 0.0 0.0005 20.3 0.0 4.9 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG12288.1 - 4.2e-08 32.3 0.0 0.00027 19.7 0.0 3.5 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAG12288.1 - 3.3e-05 22.8 0.1 0.43 9.3 0.0 3.3 3 0 0 3 3 3 3 Nup133 N terminal like BSD PF03909.17 OAG12289.1 - 1.6e-21 76.0 11.3 2.7e-12 46.5 0.1 3.4 4 0 0 4 4 4 2 BSD domain PH_TFIIH PF08567.11 OAG12289.1 - 2.7e-18 66.1 0.2 6.2e-18 64.9 0.2 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF1992 PF09350.10 OAG12293.1 - 2.8e-22 78.7 0.1 9.4e-22 77.0 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) HTH_24 PF13412.6 OAG12293.1 - 0.0043 16.6 0.0 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DUF2103 PF09876.9 OAG12293.1 - 0.12 12.3 0.0 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2103) Cellulase PF00150.18 OAG12294.1 - 1.5e-16 60.7 12.9 1.4e-15 57.5 12.9 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PGM_PMM_III PF02880.16 OAG12294.1 - 0.11 12.7 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Peptidase_S8 PF00082.22 OAG12295.1 - 1.4e-31 109.9 12.9 3.1e-31 108.7 12.9 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG12295.1 - 5.3e-10 39.8 0.1 1.9e-09 38.1 0.1 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 Fumble PF03630.14 OAG12295.1 - 0.0077 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Fumble Peptidase_S8 PF00082.22 OAG12296.1 - 6.6e-29 101.1 18.0 1.4e-28 100.1 18.0 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG12296.1 - 1.3e-06 29.0 0.1 6.2e-06 26.8 0.1 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 Cu-oxidase_2 PF07731.14 OAG12297.1 - 6.7e-42 142.5 5.2 3e-35 120.9 0.0 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG12297.1 - 1e-39 135.2 1.9 1e-39 135.2 1.9 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG12297.1 - 5.6e-34 117.6 1.6 8.1e-34 117.0 0.3 2.0 3 0 0 3 3 3 1 Multicopper oxidase PAN_4 PF14295.6 OAG12297.1 - 3.9e-07 29.9 1.5 3.9e-07 29.9 1.5 3.1 3 0 0 3 3 3 1 PAN domain Chitin_bind_1 PF00187.19 OAG12297.1 - 1.4e-05 25.5 49.1 0.0011 19.4 18.9 3.4 3 0 0 3 3 3 2 Chitin recognition protein F-box-like PF12937.7 OAG12298.1 - 0.0027 17.6 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like G-alpha PF00503.20 OAG12299.1 - 4.7e-47 160.9 0.0 4.7e-47 160.9 0.0 1.7 3 0 0 3 3 3 1 G-protein alpha subunit Arf PF00025.21 OAG12299.1 - 0.0095 15.4 0.1 0.95 8.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Nramp PF01566.18 OAG12300.1 - 6.7e-91 304.9 19.8 2.1e-88 296.7 19.8 2.3 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein ABC2_membrane PF01061.24 OAG12301.1 - 5.8e-87 290.5 55.7 4.2e-48 163.5 22.1 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAG12301.1 - 6e-38 130.5 0.0 6.9e-17 62.2 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 OAG12301.1 - 1.7e-36 124.0 1.0 2.3e-33 113.9 0.1 3.6 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG12301.1 - 1.6e-20 73.5 0.0 4.9e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAG12301.1 - 1.9e-07 31.6 0.1 0.002 18.5 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 OAG12301.1 - 1.5e-06 27.9 0.2 6.1e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG12301.1 - 3e-05 24.0 0.1 0.0024 17.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 OAG12301.1 - 0.00015 21.7 0.1 0.49 10.1 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG12301.1 - 0.00022 20.9 0.7 0.02 14.7 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 OAG12301.1 - 0.00032 20.2 0.0 0.15 11.5 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OAG12301.1 - 0.00043 20.8 0.0 0.16 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG12301.1 - 0.0018 18.4 11.0 0.045 13.9 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 OAG12301.1 - 0.0043 17.3 0.1 1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAG12301.1 - 0.018 14.7 0.8 0.24 11.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OAG12301.1 - 0.018 15.5 4.0 0.11 13.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAG12301.1 - 0.043 14.2 0.1 7 7.1 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OAG12301.1 - 0.11 12.2 0.4 13 5.5 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAG12301.1 - 0.11 12.9 0.1 27 5.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAG12301.1 - 0.23 11.4 1.8 5.6 6.9 0.4 2.7 2 0 0 2 2 2 0 NACHT domain ABC2_membrane_3 PF12698.7 OAG12301.1 - 3.8 6.5 50.2 0.21 10.6 17.8 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.32 OAG12302.1 - 6.9e-30 102.7 13.0 9.4e-05 23.1 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 OAG12302.1 - 4.5e-10 39.3 0.4 9.6e-10 38.2 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 OAG12302.1 - 6.6e-06 25.0 0.0 0.24 10.0 0.0 3.2 3 0 0 3 3 3 3 Nucleoporin Nup120/160 F-box PF00646.33 OAG12302.1 - 7.2e-06 25.8 0.1 1.2e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 OAG12302.1 - 6.4e-05 23.2 0.1 6.4 7.1 0.0 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OAG12302.1 - 0.044 13.8 0.1 30 4.7 0.0 3.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Urease_beta PF00699.20 OAG12302.1 - 0.11 12.5 0.7 16 5.6 0.0 2.7 2 0 0 2 2 2 0 Urease beta subunit WD40_like PF17005.5 OAG12302.1 - 0.14 11.5 0.3 36 3.5 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain PH_10 PF15411.6 OAG12303.1 - 3.3e-37 127.5 0.1 6.5e-37 126.5 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 OAG12303.1 - 3e-32 110.7 0.2 1.8e-31 108.2 0.0 2.2 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 OAG12303.1 - 6.1e-30 104.8 0.2 1.2e-29 103.9 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 OAG12303.1 - 6.2e-11 42.1 0.0 1.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain dDENN PF03455.19 OAG12303.1 - 0.15 12.1 0.0 0.51 10.4 0.0 1.9 1 0 0 1 1 1 0 dDENN domain OPT PF03169.15 OAG12305.1 - 5.7e-158 527.3 39.4 6.5e-158 527.1 39.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Vps36_ESCRT-II PF11605.8 OAG12307.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 K_channel_TID PF07941.11 OAG12307.1 - 0.063 13.7 1.2 0.15 12.5 1.2 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain GRAM PF02893.20 OAG12307.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 GRAM domain Pro_CA PF00484.19 OAG12309.1 - 9.5e-47 159.2 0.4 1.2e-46 158.9 0.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ThiJ_like PF17124.5 OAG12311.1 - 3.7e-53 180.2 0.0 4.5e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 OAG12311.1 - 2.6e-08 33.8 0.0 1.2e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family EthD PF07110.11 OAG12312.1 - 8.4e-15 55.7 0.0 1.2e-14 55.2 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG12312.1 - 0.00021 21.7 0.0 0.00027 21.4 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Fungal_trans_2 PF11951.8 OAG12313.1 - 0.00049 19.0 0.0 0.00069 18.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Podoplanin PF05808.11 OAG12316.1 - 0.0052 16.9 0.2 0.0089 16.1 0.2 1.4 1 0 0 1 1 1 1 Podoplanin Med3 PF11593.8 OAG12316.1 - 8.7 5.4 9.4 12 4.9 9.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltransf_11 PF08241.12 OAG12317.1 - 9.1e-13 48.7 0.1 2.1e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG12317.1 - 9.1e-12 45.5 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG12317.1 - 1.5e-09 38.5 0.0 2.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG12317.1 - 3.1e-09 36.8 0.0 4.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG12317.1 - 0.0022 17.8 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG12317.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 OAG12317.1 - 0.08 12.7 0.1 0.55 10.0 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) NodS PF05401.11 OAG12317.1 - 0.18 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF4440 PF14534.6 OAG12318.1 - 3e-09 37.2 0.0 3.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 OAG12318.1 - 0.096 12.9 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Peptidase_U4 PF03419.13 OAG12318.1 - 0.2 10.9 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA ubiquitin PF00240.23 OAG12319.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 OAG12319.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG12319.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG12319.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAG12319.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG12319.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG12319.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAG12319.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 OAG12319.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 OAG12319.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 OAG12319.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 OAG12319.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 OAG12319.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 OAG12319.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 OAG12319.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 OAG12319.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 OAG12319.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 OAG12319.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 OAG12319.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 OAG12319.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 OAG12319.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 OAG12319.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 OAG12319.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 OAG12319.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 OAG12319.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 OAG12319.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 OAG12319.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Aldo_ket_red PF00248.21 OAG12320.1 - 2.3e-66 224.0 0.1 2.6e-66 223.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 2_5_RNA_ligase2 PF13563.6 OAG12321.1 - 2e-16 60.3 0.4 2.6e-16 59.9 0.4 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily NTP_transferase PF00483.23 OAG12322.1 - 1.1e-54 185.6 0.0 2e-54 184.8 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 OAG12322.1 - 3.1e-17 61.5 14.8 2.8e-10 39.5 3.2 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAG12322.1 - 1e-11 45.4 0.0 1.3e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OAG12322.1 - 5e-06 26.2 1.8 5e-06 26.2 1.8 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 OAG12322.1 - 0.00086 17.6 0.2 0.0029 15.8 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 OAG12322.1 - 0.0042 17.0 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase IspD PF01128.19 OAG12322.1 - 0.0098 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Zn_clus PF00172.18 OAG12323.1 - 0.0046 17.0 7.5 0.012 15.8 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAM-associated PF14303.6 OAG12323.1 - 7.9 7.2 10.1 35 5.1 10.1 2.1 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Fungal_TACC PF12709.7 OAG12324.1 - 3.5 8.1 7.3 24 5.5 0.7 2.9 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cupin_2 PF07883.11 OAG12325.1 - 1.1e-07 31.4 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Prenyltrans PF00432.21 OAG12326.1 - 6.3e-35 118.6 16.4 2.5e-08 33.5 1.0 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Dabb PF07876.12 OAG12327.1 - 4.5e-05 24.0 0.0 5.2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain PSD3 PF07626.11 OAG12327.1 - 0.16 12.4 0.1 0.68 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) dsrm PF00035.26 OAG12329.1 - 0.0047 17.6 0.0 0.011 16.4 0.0 1.7 1 1 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 OAG12329.1 - 0.068 13.4 0.5 0.24 11.7 0.5 1.9 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF5423 PF17461.2 OAG12329.1 - 0.13 11.1 3.0 0.17 10.7 3.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Bindin PF02084.15 OAG12329.1 - 0.14 12.4 1.0 0.17 12.1 1.0 1.1 1 0 0 1 1 1 0 Bindin ubiquitin PF00240.23 OAG12331.1 - 6e-35 118.8 0.1 1e-22 79.6 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OAG12331.1 - 2.2e-11 43.4 0.1 2.5e-07 30.4 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OAG12331.1 - 0.0004 20.7 0.0 0.77 10.2 0.0 2.3 1 1 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG12331.1 - 0.0027 17.6 0.0 0.073 13.0 0.0 2.5 1 1 2 3 3 3 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OAG12331.1 - 0.021 15.4 0.0 1 9.9 0.0 2.2 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 OAG12331.1 - 0.022 15.2 0.0 3 8.3 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG12331.1 - 0.064 13.4 0.0 2.8 8.1 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 OAG12331.1 - 0.071 13.8 0.0 1.3 9.7 0.0 2.3 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Ribosomal_L26 PF16906.5 OAG12331.1 - 0.12 12.8 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Chitin_synth_1 PF01644.17 OAG12333.1 - 2.1e-69 232.6 0.0 3.1e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAG12333.1 - 4.4e-29 100.2 0.0 1.2e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG12333.1 - 3e-23 82.2 0.0 4.7e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG12333.1 - 2.3e-09 37.4 0.7 2.3e-09 37.4 0.7 2.6 4 1 0 4 4 4 1 Glycosyl transferase family group 2 DUF218 PF02698.17 OAG12335.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain RibD_C PF01872.17 OAG12336.1 - 4.3e-35 121.4 0.0 4.9e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain UQ_con PF00179.26 OAG12337.1 - 3.4e-36 124.0 0.0 4.4e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IlvN PF07991.12 OAG12338.1 - 5.5e-45 152.9 0.0 1.1e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 OAG12338.1 - 2.7e-40 138.0 0.1 9.9e-40 136.2 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 OAG12338.1 - 0.097 13.3 0.2 0.58 10.8 0.2 2.3 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_43 PF04616.14 OAG12339.1 - 1.6e-30 106.4 1.3 7.2e-30 104.3 1.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DAGK_cat PF00781.24 OAG12340.1 - 0.16 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Hexapep PF00132.24 OAG12341.1 - 3.6e-11 42.3 13.3 0.00013 21.6 3.7 4.3 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAG12341.1 - 5.8e-05 22.8 11.8 0.95 9.3 0.1 4.7 3 2 2 5 5 5 4 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OAG12341.1 - 0.0022 17.0 0.0 0.0045 16.0 0.1 1.4 2 0 0 2 2 2 1 L-fucokinase LPP20 PF02169.16 OAG12341.1 - 0.068 13.5 0.3 0.15 12.4 0.3 1.6 1 0 0 1 1 1 0 LPP20 lipoprotein DUF4954 PF16314.5 OAG12341.1 - 0.14 10.2 1.8 0.42 8.7 0.7 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4954) FMN_dh PF01070.18 OAG12342.1 - 1.1e-89 300.9 0.0 2e-47 161.9 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG12342.1 - 0.00052 19.1 0.1 0.0024 16.9 0.0 2.0 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG12342.1 - 0.0078 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG12342.1 - 0.018 14.5 0.3 4 6.8 0.0 3.1 1 1 2 3 3 3 0 Histidine biosynthesis protein DHO_dh PF01180.21 OAG12342.1 - 0.023 13.9 0.1 2.8 7.1 0.0 2.8 2 1 0 3 3 3 0 Dihydroorotate dehydrogenase Con-6 PF10346.9 OAG12343.1 - 4.4e-14 52.2 2.9 7.2e-14 51.5 2.9 1.4 1 0 0 1 1 1 1 Conidiation protein 6 SET PF00856.28 OAG12344.1 - 2.1e-12 47.8 0.1 3.4e-11 43.8 0.0 2.4 2 1 0 2 2 2 1 SET domain Tyrosinase PF00264.20 OAG12345.1 - 4.6e-40 138.3 7.8 2.4e-26 93.4 0.2 2.4 1 1 1 2 2 2 2 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAG12345.1 - 1.2e-11 45.4 0.0 1.9e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain FMO-like PF00743.19 OAG12346.1 - 1.6e-24 86.2 0.0 5.7e-12 44.8 0.0 3.0 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG12346.1 - 7.7e-13 48.4 0.4 1.8e-11 43.8 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG12346.1 - 1.3e-07 31.2 0.0 6e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG12346.1 - 1.5e-07 30.9 0.6 1e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG12346.1 - 0.00011 22.2 0.0 0.024 14.6 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG12346.1 - 0.031 14.5 0.1 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 OAG12347.1 - 1.6e-34 119.4 19.0 2.9e-34 118.5 18.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 OAG12347.1 - 0.15 11.9 4.3 0.62 9.8 0.2 3.3 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Cation_ATPase_C PF00689.21 OAG12347.1 - 0.24 11.1 7.6 0.33 10.7 0.0 3.5 3 1 0 3 3 3 0 Cation transporting ATPase, C-terminus Acetyltransf_10 PF13673.7 OAG12348.1 - 6.5e-10 39.0 0.0 9.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG12348.1 - 1.1e-06 28.8 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG12348.1 - 7.7e-06 26.3 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MSP1_C PF07462.11 OAG12348.1 - 0.26 9.9 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Rieske PF00355.26 OAG12349.1 - 1.6e-08 34.4 0.0 5.6e-08 32.6 0.0 1.8 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain Aldolase_II PF00596.21 OAG12350.1 - 8.6e-47 159.5 0.2 1.2e-46 159.0 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NADH_4Fe-4S PF10589.9 OAG12350.1 - 0.077 13.1 0.0 1.5 8.9 0.0 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region FMO-like PF00743.19 OAG12351.1 - 3.7e-25 88.4 0.0 1.4e-08 33.7 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG12351.1 - 1.4e-14 54.1 0.0 1.2e-09 37.9 0.1 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG12351.1 - 5e-10 39.1 0.0 8.9e-09 35.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG12351.1 - 1.9e-06 27.9 0.0 0.00031 20.8 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG12351.1 - 2e-06 27.9 0.0 9.6e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG12351.1 - 4.2e-06 26.2 0.3 0.07 12.3 0.1 3.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG12351.1 - 0.0012 18.5 0.0 0.52 9.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG12351.1 - 0.0024 17.1 0.1 0.0064 15.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OAG12351.1 - 0.0063 17.0 0.0 0.81 10.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 OAG12351.1 - 0.016 15.2 0.0 0.063 13.3 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HI0933_like PF03486.14 OAG12351.1 - 0.18 10.5 0.0 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Bac_rhamnosid6H PF17389.2 OAG12352.1 - 2.9e-95 319.4 6.2 6.4e-62 209.8 4.1 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 OAG12352.1 - 3.5e-60 202.7 0.0 7.3e-60 201.7 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 OAG12352.1 - 2.3e-33 114.2 0.0 5.4e-33 113.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 OAG12352.1 - 1.8e-24 85.3 0.7 5.3e-24 83.8 0.2 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Glyphos_transf PF04464.14 OAG12352.1 - 0.018 14.0 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase RAMA PF18755.1 OAG12352.1 - 0.13 12.7 3.0 2.8 8.4 0.3 3.3 3 0 0 3 3 3 0 Restriction Enzyme Adenine Methylase Associated MFS_1 PF07690.16 OAG12354.1 - 3.7e-11 42.5 24.9 3.7e-11 42.5 24.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG12354.1 - 4.7e-08 32.9 4.5 4.7e-08 32.9 4.5 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 OAG12354.1 - 0.11 11.4 13.1 1.3 7.8 0.4 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter TauD PF02668.16 OAG12355.1 - 1.1e-29 104.0 0.1 1.8e-29 103.4 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CopK PF11525.8 OAG12355.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein K PAPA-1 PF04795.12 OAG12356.1 - 0.03 15.1 11.7 7.6 7.4 0.1 5.2 3 2 2 5 5 5 0 PAPA-1-like conserved region PA26 PF04636.13 OAG12356.1 - 0.38 9.6 2.3 0.79 8.6 2.3 1.6 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) Epimerase PF01370.21 OAG12357.1 - 1.6e-21 76.8 0.0 2e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG12357.1 - 1.8e-16 60.5 0.0 2.4e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG12357.1 - 4e-14 52.3 0.0 5.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG12357.1 - 2e-10 40.3 0.0 2.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG12357.1 - 1.1e-07 31.4 0.1 0.00011 21.4 0.2 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG12357.1 - 0.00018 21.5 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG12357.1 - 0.0019 18.1 0.0 0.0049 16.8 0.0 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG12357.1 - 0.0023 17.1 0.0 0.051 12.7 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAG12357.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Peptidase_M20 PF01546.28 OAG12358.1 - 1.2e-31 110.0 0.0 1.8e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG12358.1 - 2.8e-11 43.3 0.0 5.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG12358.1 - 0.0072 16.0 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 RGS PF00615.19 OAG12359.1 - 8.2e-06 26.1 0.0 3.4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Sec20 PF03908.13 OAG12359.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Sec20 BTB PF00651.31 OAG12361.1 - 1.5e-06 28.4 0.2 2.9e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 OAG12362.1 - 6.6e-35 120.7 30.6 9.8e-35 120.1 30.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NmrA PF05368.13 OAG12363.1 - 1e-36 126.7 0.0 1.2e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG12363.1 - 5.1e-11 42.8 0.0 6.6e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG12363.1 - 7.8e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG12363.1 - 0.0022 17.0 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Radical_SAM PF04055.21 OAG12363.1 - 0.16 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily Asp PF00026.23 OAG12364.1 - 1.4e-61 208.7 6.7 1.7e-61 208.4 6.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG12364.1 - 9.6e-13 48.8 2.6 2.9e-10 40.7 2.6 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG12364.1 - 0.002 18.7 1.4 0.68 10.6 0.1 3.3 2 1 0 2 2 2 2 Aspartyl protease Uso1_p115_head PF04869.14 OAG12365.1 - 4.4e-110 367.7 0.0 1.7e-109 365.8 0.0 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 OAG12365.1 - 8.3e-22 77.9 35.5 8.3e-22 77.9 35.5 4.2 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region TolA_bind_tri PF16331.5 OAG12365.1 - 0.19 11.9 34.8 0.019 15.0 4.5 5.8 2 2 2 4 4 4 0 TolA binding protein trimerisation DUF4407 PF14362.6 OAG12365.1 - 2.4 7.4 62.3 0.28 10.5 24.0 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 OAG12365.1 - 3.4 8.1 19.4 4.4 7.7 1.6 5.1 4 0 0 4 4 4 0 TSC-22/dip/bun family TFIIA PF03153.13 OAG12365.1 - 8.3 6.3 39.5 12 5.7 39.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 OAG12367.1 - 2.2e-31 108.8 0.5 4.3e-31 107.9 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12367.1 - 5.5e-27 94.8 0.7 9.3e-27 94.1 0.7 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12367.1 - 1.2e-06 28.6 2.3 3.6e-06 27.0 2.3 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG12367.1 - 0.015 14.4 0.1 0.021 14.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABC_membrane PF00664.23 OAG12370.1 - 2.2e-86 289.9 17.8 3.3e-45 154.9 1.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG12370.1 - 1.2e-67 226.6 0.0 2.2e-32 112.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG12370.1 - 4.1e-15 55.8 0.3 2.6e-05 23.8 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG12370.1 - 8.6e-08 31.8 0.1 0.0092 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG12370.1 - 8.9e-08 32.5 0.1 0.024 14.9 0.0 3.7 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 OAG12370.1 - 7.9e-07 28.2 1.4 0.0061 15.4 0.0 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 OAG12370.1 - 1.5e-06 28.2 0.0 0.057 13.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 OAG12370.1 - 1.7e-06 28.5 1.8 0.034 14.5 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAG12370.1 - 2.1e-06 28.4 0.0 0.048 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAG12370.1 - 8.7e-06 25.7 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 OAG12370.1 - 2.2e-05 23.8 0.0 0.045 13.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 OAG12370.1 - 4.4e-05 23.3 4.4 0.074 12.8 0.0 3.8 4 1 0 4 4 4 2 AAA domain AAA_21 PF13304.6 OAG12370.1 - 0.00016 21.6 2.7 0.057 13.2 0.0 3.4 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 OAG12370.1 - 0.00018 21.2 0.0 0.27 10.8 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OAG12370.1 - 0.00044 20.4 0.0 0.49 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG12370.1 - 0.0011 18.6 0.0 0.98 9.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OAG12370.1 - 0.0016 19.0 0.0 3.1 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 OAG12370.1 - 0.0031 17.4 0.1 0.53 10.2 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.14 OAG12370.1 - 0.0063 16.5 0.1 5.8 6.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 OAG12370.1 - 0.0092 15.9 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 OAG12370.1 - 0.011 15.4 0.0 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAG12370.1 - 0.023 14.8 0.1 10 6.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 OAG12370.1 - 0.028 14.4 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 OAG12370.1 - 0.034 14.2 0.4 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_17 PF13207.6 OAG12370.1 - 0.087 13.3 0.1 19 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 OAG12370.1 - 0.094 12.4 0.0 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 OAG12370.1 - 0.096 12.7 0.3 14 5.8 0.0 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 OAG12370.1 - 0.16 11.1 0.0 6.4 5.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 OAG12370.1 - 0.24 10.5 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit SbcCD_C PF13558.6 OAG12370.1 - 0.49 10.7 6.8 12 6.2 0.1 4.0 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF2238 PF09997.9 OAG12370.1 - 7 6.4 7.2 9.3 6.0 0.7 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) K_oxygenase PF13434.6 OAG12371.1 - 2.7e-52 178.0 0.0 5.4e-52 177.0 0.0 1.3 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Acetyltransf_8 PF13523.6 OAG12372.1 - 2.9e-37 127.6 1.8 4.5e-37 126.9 1.8 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 OAG12373.1 - 4.2e-100 335.3 0.0 5e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG12373.1 - 1.7e-15 57.7 0.1 6.3e-15 55.9 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OAG12374.1 - 5.2e-71 239.4 0.0 7.7e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAG12374.1 - 4.4e-58 197.1 0.0 4.1e-34 118.1 0.0 3.0 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 OAG12374.1 - 3e-41 139.6 5.2 6.1e-14 52.1 0.4 4.0 4 0 0 4 4 4 3 Phosphopantetheine attachment site SAGA-Tad1 PF12767.7 OAG12375.1 - 0.0022 17.8 0.0 0.0032 17.3 0.0 1.3 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit adh_short PF00106.25 OAG12376.1 - 2.1e-34 118.7 0.1 3.3e-34 118.1 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12376.1 - 4.5e-24 85.3 0.1 6e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12376.1 - 9.1e-10 38.7 0.1 1.3e-09 38.2 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG12376.1 - 0.00024 20.6 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PCRF PF03462.18 OAG12379.1 - 9.7e-51 172.4 0.1 3.7e-50 170.5 0.0 2.0 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OAG12379.1 - 1.5e-34 118.4 2.7 3.1e-34 117.4 2.7 1.5 1 0 0 1 1 1 1 RF-1 domain G_glu_transpept PF01019.21 OAG12380.1 - 1.3e-141 472.9 0.0 1.5e-141 472.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ATP_transf PF09830.9 OAG12383.1 - 2.7e-15 56.3 0.0 4.5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase MFS_1 PF07690.16 OAG12384.1 - 0.00036 19.6 5.9 0.00044 19.3 5.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FGGY_N PF00370.21 OAG12385.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain CVNH PF08881.10 OAG12386.1 - 2.2e-26 92.5 0.2 2.4e-26 92.4 0.2 1.0 1 0 0 1 1 1 1 CVNH domain DUF2834 PF11196.8 OAG12388.1 - 2.6e-05 24.5 21.0 0.0021 18.4 0.1 4.2 4 1 0 4 4 4 2 Protein of unknown function (DUF2834) LrgB PF04172.16 OAG12388.1 - 0.021 14.4 0.6 0.079 12.5 0.6 1.9 2 0 0 2 2 2 0 LrgB-like family VKOR PF07884.14 OAG12388.1 - 3.3 7.9 6.9 5.7 7.1 0.4 2.9 3 0 0 3 3 3 0 Vitamin K epoxide reductase family Aa_trans PF01490.18 OAG12389.1 - 4e-79 266.2 27.0 4.7e-79 266.0 27.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PhoLip_ATPase_C PF16212.5 OAG12389.1 - 0.15 11.8 13.7 0.012 15.4 5.1 2.4 2 1 1 3 3 3 0 Phospholipid-translocating P-type ATPase C-terminal zf-RING_2 PF13639.6 OAG12390.1 - 4.5e-11 42.9 4.8 6.6e-11 42.4 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG12390.1 - 4.2e-09 36.6 4.0 7.4e-09 35.8 4.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG12390.1 - 2.4e-07 30.5 4.4 3.6e-07 29.9 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG12390.1 - 2.8e-06 27.2 1.5 6.7e-06 26.0 0.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG12390.1 - 5.5e-06 26.2 3.5 8.3e-06 25.6 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG12390.1 - 2.3e-05 24.1 1.0 3.7e-05 23.4 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OAG12390.1 - 2.7e-05 24.0 2.3 5.4e-05 23.1 2.4 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAG12390.1 - 8.9e-05 22.5 0.9 0.00015 21.7 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OAG12390.1 - 9.6e-05 22.2 2.2 0.00017 21.4 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG12390.1 - 0.0036 17.1 2.1 0.006 16.4 2.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAG12390.1 - 0.0049 16.5 2.3 0.0083 15.7 2.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 OAG12390.1 - 0.019 14.9 0.8 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 OAG12390.1 - 0.02 14.7 8.4 0.028 14.3 0.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 OAG12390.1 - 0.21 11.7 1.2 0.39 10.9 1.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 OAG12390.1 - 0.3 11.0 2.4 0.56 10.2 2.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 OAG12390.1 - 0.4 10.5 2.4 0.74 9.7 2.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 OAG12390.1 - 1.3 9.2 4.9 3.3 7.9 4.9 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 OAG12390.1 - 4.4 7.5 6.6 38 4.5 6.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Glyco_hydro_17 PF00332.18 OAG12391.1 - 5.9e-08 32.7 0.2 8.5e-08 32.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Flavodoxin_4 PF12682.7 OAG12391.1 - 0.052 13.3 0.1 0.092 12.4 0.1 1.4 1 0 0 1 1 1 0 Flavodoxin Zn_clus PF00172.18 OAG12392.1 - 6.9e-07 29.3 9.9 1.4e-06 28.3 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF678 PF05077.12 OAG12393.1 - 0.45 10.7 2.7 0.65 10.2 0.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF678) CDC45 PF02724.14 OAG12393.1 - 0.86 7.8 4.2 1 7.6 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein TPR_10 PF13374.6 OAG12394.1 - 2.9e-19 68.3 0.2 1.6e-09 37.3 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG12394.1 - 4.2e-12 46.2 2.2 5.6e-05 23.3 0.5 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat HET PF06985.11 OAG12394.1 - 4e-08 33.7 9.9 2.1e-06 28.2 1.0 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 OAG12394.1 - 1.9e-07 30.6 0.0 1e-06 28.2 0.0 2.1 2 1 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 OAG12394.1 - 4.9e-05 23.3 0.1 0.00017 21.6 0.1 2.0 1 1 0 1 1 1 1 NACHT domain PBP1_TM PF14812.6 OAG12394.1 - 0.0073 16.6 1.9 0.023 15.1 1.9 1.9 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4129 PF13559.6 OAG12394.1 - 0.028 14.7 1.0 0.11 12.8 1.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) AAA_16 PF13191.6 OAG12394.1 - 0.084 13.3 5.5 1 9.7 4.4 3.2 1 1 1 2 2 2 0 AAA ATPase domain adh_short PF00106.25 OAG12395.1 - 4.8e-37 127.3 0.0 7.4e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12395.1 - 2.1e-18 66.7 0.0 2.6e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12395.1 - 1.6e-05 24.9 0.0 5.7e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG12395.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAG12395.1 - 0.036 13.5 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 OAG12395.1 - 0.068 12.9 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 OAG12395.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SH3_1 PF00018.28 OAG12396.1 - 1.1e-15 56.9 0.1 1.8e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG12396.1 - 5.8e-11 42.1 0.2 1.2e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OAG12396.1 - 4.3e-08 32.7 0.0 6.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Porin_5 PF16930.5 OAG12396.1 - 0.056 11.9 0.1 0.075 11.5 0.1 1.1 1 0 0 1 1 1 0 Putative porin NMN_transporter PF04973.12 OAG12397.1 - 5.8 6.9 17.6 1 9.3 11.8 2.5 2 1 0 2 2 2 0 Nicotinamide mononucleotide transporter MFS_1 PF07690.16 OAG12398.1 - 1.3e-47 162.5 48.5 1.3e-47 162.5 48.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG12398.1 - 0.0036 16.2 0.1 0.0036 16.2 0.1 3.6 2 2 0 3 3 3 3 Sugar (and other) transporter UCH_1 PF13423.6 OAG12400.1 - 2.4e-99 333.0 0.0 3.4e-99 332.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 OAG12400.1 - 4.7e-18 66.3 0.0 9.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DUF4945 PF16303.5 OAG12400.1 - 0.04 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) Peptidase_M24 PF00557.24 OAG12401.1 - 1.2e-52 178.6 0.0 1.7e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAG12401.1 - 5.4e-39 132.7 0.0 9.7e-39 131.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SIR2 PF02146.17 OAG12402.1 - 1.7e-39 135.6 0.0 4.1e-39 134.3 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Abhydrolase_6 PF12697.7 OAG12403.1 - 3.7e-11 44.1 7.7 3.7e-11 44.1 7.7 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG12403.1 - 0.00015 21.2 0.0 0.0013 18.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG12403.1 - 0.011 15.3 0.0 0.031 13.9 0.2 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAG12403.1 - 0.14 12.3 0.0 7 6.8 0.0 2.4 2 0 0 2 2 2 0 TAP-like protein Pex14_N PF04695.13 OAG12403.1 - 2.5 8.7 10.0 4 8.1 10.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP1 PF08601.10 OAG12404.1 - 3.8e-117 392.2 15.2 3.8e-117 392.2 15.2 2.5 3 0 0 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 OAG12404.1 - 5.1e-09 36.1 10.2 9.6e-09 35.2 10.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 OAG12404.1 - 0.0038 17.8 0.2 0.0081 16.8 0.2 1.6 1 0 0 1 1 1 1 SlyX SHE3 PF17078.5 OAG12404.1 - 0.027 14.2 5.2 0.047 13.4 5.2 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 OAG12404.1 - 0.091 12.9 13.8 0.22 11.6 12.6 2.1 1 1 1 2 2 2 0 Basic region leucine zipper KLRAQ PF10205.9 OAG12404.1 - 0.12 12.7 2.4 0.25 11.6 2.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.17 OAG12404.1 - 0.12 13.0 9.5 0.22 12.1 9.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor HAUS-augmin3 PF14932.6 OAG12404.1 - 0.43 10.1 3.6 0.85 9.1 3.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Nop53 PF07767.11 OAG12404.1 - 1.3 8.4 14.0 2 7.7 14.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Agenet PF05641.12 OAG12405.1 - 0.0038 17.7 0.0 0.013 16.0 0.0 2.0 2 0 0 2 2 2 1 Agenet domain TUDOR PF00567.24 OAG12405.1 - 0.0067 16.5 0.1 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 Tudor domain GvpG PF05120.12 OAG12405.1 - 0.069 13.2 2.0 0.19 11.8 0.2 2.2 1 1 1 2 2 2 0 Gas vesicle protein G PCRF PF03462.18 OAG12405.1 - 1.9 8.3 7.5 0.56 10.0 3.5 1.9 2 0 0 2 2 2 0 PCRF domain Glyoxalase_3 PF13468.6 OAG12406.1 - 8.8e-31 107.4 0.0 1.1e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain DUF2967 PF11179.8 OAG12406.1 - 0.34 9.0 0.4 0.47 8.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Zn_clus PF00172.18 OAG12407.1 - 3.7e-08 33.4 7.8 6.2e-08 32.6 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HOOK PF05622.12 OAG12407.1 - 0.00034 18.9 0.1 0.00055 18.2 0.1 1.2 1 0 0 1 1 1 1 HOOK protein DUF3504 PF12012.8 OAG12407.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Fasciclin PF02469.22 OAG12408.1 - 3.1e-30 105.0 0.0 2.9e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_16 PF00722.21 OAG12409.1 - 0.00038 20.0 0.0 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF5106 PF17127.4 OAG12409.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Cupin_8 PF13621.6 OAG12410.1 - 6.7e-32 111.2 0.0 9e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAG12410.1 - 4.2e-06 26.4 0.0 5.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 OAG12410.1 - 0.0054 17.1 0.1 0.054 13.9 0.0 2.5 3 0 0 3 3 3 1 JmjC domain, hydroxylase IFT43 PF15305.6 OAG12410.1 - 0.068 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Intraflagellar transport protein 43 DUF2515 PF10720.9 OAG12411.1 - 0.17 11.0 0.5 0.26 10.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) Reticulon PF02453.17 OAG12413.1 - 1.7e-32 112.6 2.9 2.5e-32 112.0 2.9 1.3 1 0 0 1 1 1 1 Reticulon ZFYVE21_C PF16696.5 OAG12413.1 - 0.049 13.5 0.5 1.6 8.6 0.2 2.7 3 0 0 3 3 3 0 Zinc finger FYVE domain-containing protein 21 C-terminus DUF4407 PF14362.6 OAG12413.1 - 0.12 11.7 2.7 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) V-ATPase_G_2 PF16999.5 OAG12413.1 - 1.1 9.7 5.3 0.47 10.9 1.1 2.1 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit EamA PF00892.20 OAG12414.1 - 4.7e-12 46.3 26.5 7.7e-09 35.8 11.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family DMT_YdcZ PF04657.13 OAG12414.1 - 0.17 12.2 23.1 0.24 11.6 12.5 2.5 1 1 2 3 3 3 0 Putative inner membrane exporter, YdcZ Sugar_tr PF00083.24 OAG12416.1 - 4.5e-85 286.2 24.1 5.5e-85 285.9 24.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG12416.1 - 9.3e-25 87.3 47.3 2e-18 66.4 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG12416.1 - 5.6e-06 24.9 11.2 7.4e-05 21.2 3.1 2.9 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family NUDIX PF00293.28 OAG12416.1 - 0.012 15.6 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 NUDIX domain Aspzincin_M35 PF14521.6 OAG12417.1 - 7.6e-25 88.1 1.3 9.7e-25 87.8 1.3 1.1 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M43 PF05572.13 OAG12417.1 - 0.0029 17.5 0.1 0.0041 17.0 0.1 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A His_Phos_1 PF00300.22 OAG12418.1 - 9.7e-17 61.3 0.1 2e-15 57.0 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.24 OAG12422.1 - 7.5e-83 278.9 24.5 8.7e-83 278.7 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG12422.1 - 6.8e-18 64.7 31.2 6.8e-18 64.7 31.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Ferritin_2 PF13668.6 OAG12426.1 - 1.2e-41 142.1 3.7 1.7e-41 141.6 3.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain IF-2B PF01008.17 OAG12427.1 - 5.6e-27 94.7 0.0 7.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family EMP24_GP25L PF01105.24 OAG12430.1 - 2.5e-41 141.6 0.0 2.8e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 OAG12430.1 - 0.09 10.9 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Tannase PF07519.11 OAG12431.1 - 1.6e-100 337.3 2.4 1.8e-100 337.1 2.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG12431.1 - 5.7e-06 26.0 0.0 0.0044 16.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG12431.1 - 0.0021 17.4 0.0 0.035 13.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Glyco_hydro_3_C PF01915.22 OAG12433.1 - 1e-24 87.6 0.0 1.3e-24 87.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG12434.1 - 0.036 13.4 0.0 0.039 13.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain DUF3500 PF12006.8 OAG12435.1 - 1.4e-103 346.5 0.0 1.7e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAA_hydrolase PF01557.18 OAG12436.1 - 1.6e-52 178.3 0.0 2.2e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 OAG12437.1 - 1e-19 70.6 0.3 1.8e-19 69.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG12437.1 - 4e-07 30.0 10.6 9.7e-07 28.8 10.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain B12-binding PF02310.19 OAG12438.1 - 0.0015 18.6 0.1 0.0021 18.1 0.1 1.3 1 0 0 1 1 1 1 B12 binding domain RmlD_sub_bind PF04321.17 OAG12438.1 - 0.034 13.3 0.1 0.039 13.1 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain FAD_binding_3 PF01494.19 OAG12439.1 - 1.4e-26 93.6 0.0 2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG12439.1 - 6.3e-11 42.5 3.2 5.6e-05 22.9 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG12439.1 - 3.3e-09 36.4 0.2 3.2e-05 23.3 0.7 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG12439.1 - 2.3e-07 30.3 2.5 2.7e-06 26.8 1.7 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG12439.1 - 9.9e-07 27.8 0.5 1.1e-05 24.4 0.5 2.0 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG12439.1 - 7.1e-05 23.0 2.0 0.00019 21.6 2.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG12439.1 - 0.00011 22.7 0.0 0.012 16.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG12439.1 - 0.00024 20.3 0.8 0.00034 19.8 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG12439.1 - 0.00057 18.9 0.3 0.0015 17.5 0.2 1.5 1 1 1 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 OAG12439.1 - 0.0013 18.2 2.1 0.0019 17.7 2.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG12439.1 - 0.0016 17.6 0.2 0.006 15.7 0.2 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG12439.1 - 0.009 15.3 0.5 0.014 14.6 0.5 1.2 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 OAG12439.1 - 0.045 13.6 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 OAG12439.1 - 0.073 12.3 0.2 10 5.2 0.2 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase SE PF08491.10 OAG12439.1 - 0.12 11.4 0.0 0.91 8.5 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 OAG12439.1 - 0.23 10.7 0.0 0.41 9.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 OAG12440.1 - 1.2e-59 202.4 29.2 1.3e-59 202.2 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG12440.1 - 2.8e-20 72.6 36.2 2.8e-20 72.6 36.2 2.5 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG12440.1 - 1.9e-06 26.7 31.0 0.00064 18.4 10.9 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein AA_permease_C PF13906.6 OAG12440.1 - 0.68 10.1 8.0 1.6 8.9 0.8 3.4 2 0 0 2 2 2 0 C-terminus of AA_permease Abhydrolase_3 PF07859.13 OAG12441.1 - 2.9e-19 69.8 0.0 9e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG12441.1 - 4.8e-11 42.6 0.0 8.5e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAG12441.1 - 1.5e-05 24.9 0.0 0.029 14.2 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 OAG12441.1 - 2.4e-05 24.1 0.0 0.0001 22.0 0.0 1.9 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OAG12441.1 - 0.00027 20.5 0.0 0.065 12.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OAG12441.1 - 0.00045 20.9 0.1 0.00058 20.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG12441.1 - 0.0018 17.6 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 COesterase PF00135.28 OAG12441.1 - 0.0022 16.9 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 OAG12441.1 - 0.0038 16.8 0.1 0.52 9.8 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 OAG12441.1 - 0.0074 16.0 0.1 2.2 7.8 0.1 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Cupin_2 PF07883.11 OAG12442.1 - 8.4e-14 51.0 0.2 2.4e-09 36.8 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 OAG12442.1 - 4.7e-05 23.0 0.2 0.18 11.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Ppnp PF06865.11 OAG12442.1 - 0.0013 19.1 0.0 0.0039 17.6 0.0 1.8 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase AraC_binding PF02311.19 OAG12442.1 - 0.0016 18.4 0.1 0.041 13.8 0.1 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain GatD_N PF18195.1 OAG12442.1 - 0.049 13.0 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 GatD N-terminal domain Cupin_4 PF08007.12 OAG12442.1 - 0.084 12.3 0.5 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_1 PF00190.22 OAG12442.1 - 0.13 11.9 0.1 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 Cupin adh_short_C2 PF13561.6 OAG12443.1 - 4.5e-51 173.6 0.1 5.7e-51 173.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG12443.1 - 6.6e-41 139.9 0.0 8.2e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG12443.1 - 9.8e-13 48.4 0.1 1.5e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG12443.1 - 0.00038 20.0 0.0 0.00053 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG12443.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG12443.1 - 0.033 13.2 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HATPase_c PF02518.26 OAG12443.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.16 OAG12445.1 - 2.1e-22 79.6 24.4 2.2e-21 76.2 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 OAG12447.1 - 1.1e-11 44.4 0.6 1.6e-11 43.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF2264 PF10022.9 OAG12448.1 - 3.7e-136 453.9 2.2 4.5e-136 453.6 2.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans PF04082.18 OAG12449.1 - 2e-09 36.9 0.7 9.4e-09 34.7 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG12449.1 - 3.7e-09 36.6 9.8 7.7e-09 35.5 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAG12450.1 - 3.2e-36 124.8 0.1 5.2e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 OAG12451.1 - 1.2e-13 51.1 0.0 1.2e-12 47.7 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG12451.1 - 3.7e-06 26.7 0.0 0.00028 20.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG12451.1 - 0.00019 21.5 0.0 0.00058 19.9 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG12451.1 - 0.0023 17.1 0.0 0.33 10.0 0.0 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG12451.1 - 0.0035 17.6 2.0 0.04 14.2 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAG12451.1 - 0.0083 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 OAG12451.1 - 0.094 11.9 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SAPS PF04499.15 OAG12452.1 - 9.6e-192 638.1 0.3 3.1e-191 636.4 0.1 1.9 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein baeRF_family7 PF18849.1 OAG12452.1 - 0.067 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 Snf7 PF03357.21 OAG12454.1 - 1.8e-45 154.6 16.0 2.1e-45 154.4 16.0 1.0 1 0 0 1 1 1 1 Snf7 DUF5082 PF16888.5 OAG12454.1 - 0.0036 17.6 9.8 0.057 13.7 5.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) CLZ PF16526.5 OAG12454.1 - 0.012 15.9 8.8 0.043 14.2 0.0 3.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4201 PF13870.6 OAG12454.1 - 0.025 14.3 12.4 0.039 13.7 10.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) AF0941-like PF14591.6 OAG12454.1 - 0.088 13.4 5.9 0.14 12.7 5.9 1.3 1 0 0 1 1 1 0 AF0941-like HSDR_N PF04313.14 OAG12454.1 - 0.14 12.1 2.4 0.17 11.8 1.3 1.6 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Prefoldin PF02996.17 OAG12454.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.6 2 1 2 4 4 4 0 Prefoldin subunit NPV_P10 PF05531.12 OAG12454.1 - 0.17 12.4 12.3 0.38 11.3 1.5 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 OAG12454.1 - 0.22 11.9 7.0 12 6.4 0.0 3.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF848 PF05852.11 OAG12454.1 - 0.32 11.1 8.5 0.38 10.9 5.5 2.4 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) BORCS7 PF16088.5 OAG12454.1 - 0.46 10.8 7.4 0.21 11.9 3.1 2.4 1 1 1 3 3 3 0 BLOC-1-related complex sub-unit 7 DUF2120 PF09893.9 OAG12454.1 - 0.89 9.7 4.4 0.99 9.5 3.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) DASH_Dam1 PF08653.10 OAG12454.1 - 1.5 8.6 4.1 5.5 6.9 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 FapA PF03961.13 OAG12454.1 - 1.6 7.2 11.8 4.8 5.7 2.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF948 PF06103.11 OAG12454.1 - 1.7 9.0 5.9 3.4 8.0 2.6 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 OAG12454.1 - 3.5 6.6 9.4 15 4.5 9.5 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 OAG12454.1 - 3.7 7.2 12.6 1.1 8.9 8.0 2.1 1 1 0 2 2 2 0 GrpE HrpB7 PF09486.10 OAG12454.1 - 5 7.5 11.5 0.5 10.8 0.4 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.6 OAG12454.1 - 6.3 6.1 10.9 11 5.2 10.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PAN_4 PF14295.6 OAG12455.1 - 0.012 15.5 2.4 0.03 14.2 1.2 2.2 2 0 0 2 2 2 0 PAN domain Suc_Fer-like PF06999.12 OAG12456.1 - 5.7e-72 241.7 0.0 7.1e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like REPA_OB_2 PF16900.5 OAG12457.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Replication protein A OB domain Ste5 PF11610.8 OAG12457.1 - 0.021 14.7 0.2 0.053 13.4 0.2 1.6 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region Tyrosinase PF00264.20 OAG12458.1 - 1.5e-45 156.2 0.8 1.5e-45 156.2 0.8 2.1 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAG12458.1 - 1.6e-23 83.6 0.0 3.1e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain Response_reg PF00072.24 OAG12460.1 - 2.4e-14 53.4 0.0 5.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG12460.1 - 3.1e-14 53.4 0.0 6.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG12460.1 - 1e-09 38.3 0.0 3e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OAG12460.1 - 0.0077 16.1 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2489 PF10675.9 OAG12460.1 - 0.057 13.3 0.2 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) ADH_zinc_N PF00107.26 OAG12461.1 - 7.4e-25 87.4 0.8 1.3e-24 86.6 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG12461.1 - 2.4e-13 51.3 0.2 4.5e-13 50.4 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG12461.1 - 0.00013 21.5 0.8 0.00027 20.5 0.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 OAG12461.1 - 0.00033 20.5 0.2 0.001 18.9 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 OAG12461.1 - 0.00051 20.0 0.3 0.00082 19.3 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AAA_30 PF13604.6 OAG12461.1 - 0.0056 16.4 0.5 0.0082 15.9 0.5 1.4 1 0 0 1 1 1 1 AAA domain ACP_syn_III_C PF08541.10 OAG12461.1 - 0.68 10.1 2.4 1.3 9.2 0.8 2.1 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MFS_1 PF07690.16 OAG12462.1 - 4.4e-21 75.2 9.3 6.1e-21 74.7 9.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 OAG12463.1 - 5.9e-57 193.5 0.4 7.4e-57 193.2 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aha1_N PF09229.11 OAG12464.1 - 3.8e-42 143.7 1.9 5.8e-42 143.1 1.9 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 OAG12464.1 - 1.7e-18 67.0 1.3 1.7e-18 67.0 1.3 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein CYYR1 PF10873.8 OAG12468.1 - 3.4 8.1 9.8 49 4.3 9.8 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 HECT PF00632.25 OAG12469.1 - 6.5e-80 268.9 0.0 1e-79 268.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 OAG12469.1 - 0.002 17.7 0.4 0.0074 16.0 0.4 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Peptidase_S10 PF00450.22 OAG12474.1 - 2e-96 324.0 2.9 2.4e-96 323.7 2.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Dynamin_N PF00350.23 OAG12477.1 - 3.1e-05 24.1 0.1 0.00024 21.2 0.0 2.5 2 1 0 2 2 2 1 Dynamin family DUF87 PF01935.17 OAG12477.1 - 0.28 11.2 4.4 0.46 10.5 0.2 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Glyco_tran_28_C PF04101.16 OAG12478.1 - 7.1e-16 58.6 0.0 9.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TPP_enzyme_N PF02776.18 OAG12478.1 - 0.029 14.0 0.1 0.076 12.6 0.0 1.7 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain UDPGT PF00201.18 OAG12478.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase T2SSM_b PF10741.9 OAG12478.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b MRP-S28 PF10213.9 OAG12479.1 - 4.1e-44 150.1 0.0 6.6e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ino80_Iec3 PF14612.6 OAG12480.1 - 3.6e-67 227.5 1.7 4.6e-67 227.1 1.7 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling GvpG PF05120.12 OAG12480.1 - 0.00031 20.7 0.6 0.00077 19.4 0.2 1.8 1 1 1 2 2 2 1 Gas vesicle protein G SHOCT PF09851.9 OAG12480.1 - 0.013 15.2 1.0 0.025 14.3 0.1 2.0 2 0 0 2 2 2 0 Short C-terminal domain DUF1707 PF08044.11 OAG12480.1 - 0.026 14.6 2.3 0.032 14.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) DMAP_binding PF06464.11 OAG12480.1 - 0.03 15.2 0.3 0.12 13.2 0.0 2.1 2 0 0 2 2 2 0 DMAP1-binding Domain ORMDL PF04061.14 OAG12481.1 - 5.9e-55 184.8 1.1 5.9e-55 184.8 1.1 2.2 2 0 0 2 2 2 1 ORMDL family Na_H_Exchanger PF00999.21 OAG12481.1 - 2.5e-52 178.0 29.1 4.1e-52 177.2 29.1 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ATP-synt_Z PF16594.5 OAG12481.1 - 0.0055 16.2 1.5 0.076 12.5 0.0 2.7 2 0 0 2 2 2 1 Putative AtpZ or ATP-synthase-associated GtrA PF04138.14 OAG12481.1 - 0.18 12.1 12.2 0.033 14.4 5.7 2.8 2 1 0 2 2 2 0 GtrA-like protein Glyco_hydro_28 PF00295.17 OAG12482.1 - 8.7e-46 156.5 10.6 1.3e-45 155.9 10.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Asparaginase PF00710.20 OAG12483.1 - 6.5e-31 107.4 0.0 9.1e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG12483.1 - 2.2e-11 44.0 0.1 4.4e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain PA PF02225.22 OAG12483.1 - 0.082 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 PA domain DUF737 PF05300.11 OAG12484.1 - 0.037 14.4 0.3 0.056 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) MFS_1 PF07690.16 OAG12485.1 - 3e-36 125.1 18.5 4.3e-36 124.6 18.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG12485.1 - 2.3e-05 23.9 5.5 2.3e-05 23.9 5.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1230 PF06799.11 OAG12485.1 - 0.023 14.8 1.7 0.17 12.0 0.0 2.7 3 0 0 3 3 3 0 Conserved in the green lineage and diatoms 27 Saf_2TM PF18303.1 OAG12485.1 - 0.19 11.3 0.4 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF2929 PF11151.8 OAG12485.1 - 2.1 8.7 6.5 2.7 8.3 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2929) Brix PF04427.18 OAG12486.1 - 4.7e-30 105.1 0.0 6e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain RPA43_OB PF17875.1 OAG12487.1 - 1.6e-16 61.0 3.1 2.8e-16 60.3 0.8 2.3 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OAG12487.1 - 0.00039 20.7 0.0 0.0009 19.6 0.0 1.7 1 1 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 OB_NTP_bind PF07717.16 OAG12488.1 - 4.9e-23 81.3 0.0 1.3e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAG12488.1 - 1.2e-18 67.3 0.0 3.1e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG12488.1 - 7.6e-10 39.1 0.0 2.4e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG12488.1 - 6.1e-07 29.4 0.2 1.3e-06 28.3 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG12488.1 - 1.8e-06 28.3 0.1 5.2e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OAG12488.1 - 0.00046 19.9 0.2 0.0012 18.5 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 OAG12488.1 - 0.0035 17.7 0.2 0.0082 16.5 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG12488.1 - 0.0056 16.4 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 OAG12488.1 - 0.01 15.8 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_23 PF13476.6 OAG12488.1 - 0.015 15.8 0.0 0.049 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG12488.1 - 0.032 13.7 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 OAG12488.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PRMT5_TIM PF17285.2 OAG12489.1 - 2.4e-70 236.7 0.0 3.1e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 OAG12489.1 - 7.5e-69 231.0 0.0 1.4e-68 230.1 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 OAG12489.1 - 2.1e-57 193.8 0.0 3.4e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 OAG12489.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein FAD_binding_4 PF01565.23 OAG12490.1 - 4.5e-29 101.0 1.0 7.9e-29 100.2 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG12490.1 - 4.8e-13 49.0 0.0 1.1e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Zincin_1 PF06262.11 OAG12490.1 - 0.18 11.9 0.0 5.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Zincin-like metallopeptidase Skp1_POZ PF03931.15 OAG12492.1 - 3.4e-10 39.9 0.0 5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF5424 PF17462.2 OAG12492.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5424) adh_short PF00106.25 OAG12493.1 - 6.8e-45 152.9 0.0 9e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12493.1 - 7.7e-44 150.0 0.1 9.8e-44 149.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12493.1 - 3.1e-07 30.5 0.1 7.4e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 KR domain Med12-LCEWAV PF12145.8 OAG12493.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain ThiF PF00899.21 OAG12494.1 - 1.1e-73 247.5 0.0 1.9e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 OAG12494.1 - 2.4e-19 69.7 0.0 7.1e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 OAG12494.1 - 3.6e-09 36.9 2.3 3.2e-05 24.0 0.7 2.5 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 OAG12494.1 - 2.4e-05 24.7 1.2 0.001 19.5 0.0 3.0 2 1 1 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG12494.1 - 0.0034 17.4 0.3 0.012 15.6 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG12494.1 - 0.053 13.8 1.1 0.23 11.7 0.1 2.7 3 1 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG12494.1 - 0.11 13.0 0.2 2.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Q_salvage PF10343.9 OAG12495.1 - 1.8e-124 414.9 0.0 1.8e-92 309.9 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Myb_DNA-bind_3 PF12776.7 OAG12496.1 - 1.3e-05 26.1 0.0 1.7e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Tox-SGS PF15651.6 OAG12496.1 - 0.047 13.9 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin DUF2827 PF10933.8 OAG12496.1 - 0.055 12.1 0.0 0.059 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Myb_DNA-bind_4 PF13837.6 OAG12496.1 - 0.085 13.3 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Aminotran_4 PF01063.19 OAG12497.1 - 3.8e-19 69.5 0.0 5.4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV DUF3431 PF11913.8 OAG12500.1 - 1.1e-13 51.5 0.2 2.2e-13 50.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Tetraspanin PF00335.20 OAG12500.1 - 0.0027 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Tetraspanin family CRCB PF02537.15 OAG12500.1 - 0.059 13.7 0.2 0.15 12.4 0.2 1.7 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) 5TM-5TMR_LYT PF07694.12 OAG12500.1 - 0.12 11.8 3.4 0.082 12.4 0.6 2.2 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Fringe PF02434.16 OAG12501.1 - 2.4e-08 33.8 0.1 6.6e-08 32.3 0.1 1.6 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 OAG12501.1 - 0.019 14.9 0.2 0.052 13.5 0.2 1.7 1 0 0 1 1 1 0 PAN domain p450 PF00067.22 OAG12502.1 - 1.2e-51 175.9 0.0 1.7e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nuc_deoxyri_tr3 PF11071.8 OAG12502.1 - 0.14 12.2 0.2 0.26 11.3 0.2 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Beta-lactamase PF00144.24 OAG12503.1 - 4.5e-50 170.8 1.2 8.2e-50 169.9 1.2 1.4 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 OAG12503.1 - 6.9e-12 45.7 0.1 1.3e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) FSH1 PF03959.13 OAG12506.1 - 8.6e-29 100.7 0.0 1.3e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAG12506.1 - 0.00024 21.8 0.0 0.00037 21.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Phosphonate-bd PF12974.7 OAG12506.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.16 OAG12507.1 - 3.7e-26 91.9 44.6 1e-25 90.5 44.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG12507.1 - 0.00031 19.3 22.5 0.00061 18.3 22.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4149 PF13664.6 OAG12507.1 - 0.021 15.1 3.0 0.021 15.1 3.0 4.7 4 2 2 6 6 6 0 Domain of unknown function (DUF4149) PhoU_div PF01865.16 OAG12507.1 - 0.22 10.8 0.1 0.34 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 ketoacyl-synt PF00109.26 OAG12508.1 - 1.2e-67 228.2 0.0 2e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OAG12508.1 - 7.2e-63 211.7 0.0 1.8e-62 210.5 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 OAG12508.1 - 1.9e-43 148.8 0.0 3.1e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 OAG12508.1 - 2.5e-36 125.8 0.1 9.5e-36 123.9 0.1 1.9 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG12508.1 - 5.1e-33 113.6 0.0 1.7e-32 111.9 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAG12508.1 - 8.6e-21 74.5 0.0 2.8e-20 72.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG12508.1 - 1.2e-16 61.1 0.0 1.1e-15 58.1 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 OAG12508.1 - 5e-16 58.9 0.0 5e-15 55.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG12508.1 - 4.2e-13 49.8 0.0 2.4e-12 47.4 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 OAG12508.1 - 6.8e-13 49.8 0.0 6.1e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 OAG12508.1 - 8e-13 48.6 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 OAG12508.1 - 1.6e-12 47.5 0.2 7.8e-12 45.3 0.1 2.3 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 OAG12508.1 - 5.1e-12 46.3 0.0 1.5e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG12508.1 - 1.5e-08 34.3 0.0 4.1e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 OAG12508.1 - 4.9e-08 33.2 0.1 2.4e-07 31.0 0.1 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OAG12508.1 - 9.9e-07 28.4 1.0 1.5e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase SAT PF16073.5 OAG12508.1 - 0.00031 20.5 0.6 0.0018 18.1 0.6 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 OAG12508.1 - 0.001 18.5 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_2 PF00891.18 OAG12508.1 - 0.0034 16.7 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain ADH_N PF08240.12 OAG12508.1 - 0.01 15.7 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Pox_MCEL PF03291.16 OAG12508.1 - 0.09 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Trs65 PF12735.7 OAG12509.1 - 5.7e-78 262.5 0.1 8.1e-78 262.0 0.1 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 A2M PF00207.22 OAG12509.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin family FF PF01846.19 OAG12510.1 - 4.8e-42 141.9 24.1 1.7e-12 47.3 3.4 6.9 7 0 0 7 7 7 4 FF domain WW PF00397.26 OAG12510.1 - 5.2e-13 48.8 14.6 1.5e-08 34.6 1.6 3.0 3 0 0 3 3 3 2 WW domain RhoGAP-FF1 PF16512.5 OAG12510.1 - 0.00036 21.1 16.3 0.035 14.8 3.2 4.9 2 1 2 4 4 4 2 p190-A and -B Rho GAPs FF domain DUF5340 PF17275.2 OAG12510.1 - 0.2 11.8 1.6 0.3 11.2 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5340) ABC_tran PF00005.27 OAG12511.1 - 2.7e-35 121.8 0.0 2.1e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG12511.1 - 9.8e-12 45.3 3.2 0.064 13.1 0.0 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG12511.1 - 7.2e-10 38.7 4.7 0.0046 16.4 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 OAG12511.1 - 1.6e-06 28.2 0.1 0.023 14.6 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 OAG12511.1 - 6.7e-06 26.0 0.4 0.16 11.6 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 OAG12511.1 - 7.2e-06 26.5 0.1 0.014 15.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG12511.1 - 9.2e-06 26.0 0.0 0.0028 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG12511.1 - 0.00014 22.3 0.0 0.11 12.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 OAG12511.1 - 0.00015 21.7 0.1 0.3 11.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OAG12511.1 - 0.00018 21.9 0.0 0.066 13.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 OAG12511.1 - 0.00042 20.1 0.9 0.081 12.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG12511.1 - 0.00079 20.0 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 OAG12511.1 - 0.00085 19.0 3.3 0.029 14.0 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OAG12511.1 - 0.0024 18.0 0.0 0.64 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG12511.1 - 0.0028 17.6 1.9 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 OAG12511.1 - 0.0038 16.9 0.2 2.5 7.8 0.0 2.9 3 0 0 3 3 3 1 Thymidylate kinase AAA_29 PF13555.6 OAG12511.1 - 0.0042 16.8 0.5 2.9 7.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain TsaE PF02367.17 OAG12511.1 - 0.0043 17.1 0.6 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OAG12511.1 - 0.005 16.4 1.0 0.069 12.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 OAG12511.1 - 0.0053 17.3 3.9 0.088 13.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG12511.1 - 0.0065 16.2 0.2 0.72 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 OAG12511.1 - 0.01 14.6 1.0 0.014 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 OAG12511.1 - 0.01 15.0 0.2 1 8.5 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.14 OAG12511.1 - 0.011 15.7 0.1 0.89 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAG12511.1 - 0.014 15.6 0.1 3.6 7.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain VirE PF05272.11 OAG12511.1 - 0.038 13.7 0.0 6.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Virulence-associated protein E DnaB_C PF03796.15 OAG12511.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 OAG12511.1 - 0.068 13.2 0.9 3.7 7.6 0.0 3.0 2 2 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OAG12511.1 - 0.088 12.7 2.3 3.1 7.7 0.1 3.0 3 0 0 3 3 3 0 NTPase Rad51 PF08423.11 OAG12511.1 - 0.11 11.7 0.2 0.94 8.7 0.1 2.1 2 0 0 2 2 2 0 Rad51 ATPase PF06745.13 OAG12511.1 - 0.12 11.7 0.1 0.28 10.5 0.1 1.6 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 OAG12511.1 - 0.16 12.0 0.8 28 4.8 0.4 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase CLP1_P PF16575.5 OAG12511.1 - 0.2 11.4 0.5 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 OAG12511.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.4 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation MukB PF04310.12 OAG12511.1 - 0.35 10.6 2.6 17 5.1 0.1 2.9 3 0 0 3 3 3 0 MukB N-terminal Zeta_toxin PF06414.12 OAG12511.1 - 0.46 9.7 1.7 7.8 5.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin SNF2_N PF00176.23 OAG12512.1 - 4.8e-55 186.7 0.0 8.8e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 OAG12512.1 - 2e-24 85.3 5.3 2.5e-15 56.1 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 OAG12512.1 - 5.4e-19 68.6 0.0 1.5e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 OAG12512.1 - 1.1e-15 57.9 0.2 4.2e-15 56.0 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) ResIII PF04851.15 OAG12512.1 - 6e-06 26.4 0.0 6.4e-05 23.0 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG12512.1 - 0.0002 21.2 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cdh1_DBD_1 PF18196.1 OAG12512.1 - 0.00069 19.9 2.4 0.0083 16.4 0.2 5.4 6 1 1 7 7 7 2 Chromodomain helicase DNA-binding domain 1 CHDCT2 PF08074.11 OAG12512.1 - 0.013 15.7 2.1 0.098 12.8 0.0 2.9 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain AAA_22 PF13401.6 OAG12512.1 - 0.1 12.8 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 OAG12513.1 - 2.4e-08 34.7 0.9 4.4e-08 33.9 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PHBC_N PF12551.8 OAG12513.1 - 0.19 11.5 0.2 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal bZIP_1 PF00170.21 OAG12518.1 - 0.00033 20.7 8.3 0.00052 20.0 8.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG12518.1 - 0.0045 17.1 7.8 0.0068 16.5 7.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG12518.1 - 0.034 14.7 4.7 0.059 13.9 4.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor AAA PF00004.29 OAG12519.1 - 4.9e-15 56.1 0.0 9.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 OAG12519.1 - 1.2e-12 47.8 0.4 1.1e-11 44.7 0.1 2.3 2 0 0 2 2 2 1 AAA lid domain AAA_22 PF13401.6 OAG12519.1 - 6.6e-11 42.6 0.0 4.8e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG12519.1 - 5.5e-10 39.9 0.0 2.5e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.18 OAG12519.1 - 1.4e-08 34.7 0.1 3.9e-08 33.2 0.1 1.8 2 0 0 2 2 1 1 BAH domain AAA_19 PF13245.6 OAG12519.1 - 0.00053 20.3 0.0 0.0044 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG12519.1 - 0.0051 16.7 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AT_hook PF02178.19 OAG12519.1 - 0.0055 16.4 1.0 0.024 14.4 1.0 2.2 1 0 0 1 1 1 1 AT hook motif AAA_11 PF13086.6 OAG12519.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG12519.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 OAG12519.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Baculo_11_kDa PF06143.11 OAG12519.1 - 0.12 12.0 0.1 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF2075 PF09848.9 OAG12519.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.6 OAG12519.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG12519.1 - 0.17 11.8 0.0 7 6.5 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea WD40 PF00400.32 OAG12522.1 - 1.9e-46 155.0 16.4 6.3e-10 39.5 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG12522.1 - 7.9e-07 29.3 0.7 0.98 9.8 0.0 5.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG12522.1 - 0.0084 14.8 4.9 11 4.5 0.0 4.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG12522.1 - 0.054 12.8 0.0 0.26 10.6 0.0 2.1 2 1 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 OAG12522.1 - 0.077 11.7 0.0 4 6.1 0.0 3.0 1 1 2 3 3 3 0 Nup133 N terminal like DUF423 PF04241.15 OAG12523.1 - 8.7e-26 89.9 0.7 1.2e-25 89.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Esterase PF00756.20 OAG12524.1 - 0.00045 19.9 0.2 0.0024 17.6 0.2 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAG12524.1 - 0.0008 19.3 0.2 0.0033 17.3 0.1 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 OAG12524.1 - 0.032 13.8 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 OAG12524.1 - 0.034 13.6 0.4 0.084 12.4 0.2 1.6 1 1 1 2 2 2 0 Esterase PHB depolymerase DLH PF01738.18 OAG12524.1 - 0.054 13.0 0.2 0.15 11.6 0.1 1.7 1 1 1 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG12524.1 - 0.055 12.9 0.3 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG12524.1 - 0.24 11.0 1.9 0.34 10.5 1.4 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ribonuc_P_40 PF08584.11 OAG12526.1 - 1.3e-65 221.6 0.0 1.7e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit SIR2 PF02146.17 OAG12527.1 - 1.6e-55 187.8 0.0 2.1e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OAG12527.1 - 3.2e-05 23.7 0.1 0.022 14.5 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 OAG12527.1 - 0.00021 21.1 0.0 0.00066 19.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF592) CutC PF03932.14 OAG12527.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 CutC family Zn_clus PF00172.18 OAG12529.1 - 2.1e-05 24.5 15.7 3.7e-05 23.8 15.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG12529.1 - 0.0003 19.7 0.2 0.00047 19.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 OAG12530.1 - 2.4e-60 203.7 4.6 2.4e-60 203.7 4.6 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF5367 PF17329.2 OAG12530.1 - 0.057 13.5 0.2 0.057 13.5 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5367) DUF4173 PF13777.6 OAG12530.1 - 0.1 12.0 4.9 0.073 12.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) BCD PF15461.6 OAG12530.1 - 0.26 10.8 10.6 1.4 8.4 0.4 2.7 2 1 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase YrhC PF14143.6 OAG12530.1 - 0.42 10.7 0.1 0.42 10.7 0.1 3.2 4 0 0 4 4 4 0 YrhC-like protein TMEM154 PF15102.6 OAG12530.1 - 0.89 9.5 0.1 0.89 9.5 0.1 2.5 3 0 0 3 3 3 0 TMEM154 protein family EphA2_TM PF14575.6 OAG12530.1 - 1.9 9.4 6.5 1 10.3 0.1 2.8 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 OAG12530.1 - 6.3 6.4 7.6 0.17 11.5 0.4 2.2 2 1 0 2 2 2 0 Baculovirus 11 kDa family FixQ PF05545.11 OAG12530.1 - 6.8 6.8 12.4 2.4 8.2 1.6 3.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Cation_ATPase PF13246.6 OAG12532.1 - 2.4e-08 33.9 0.0 3.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAG12532.1 - 1.3e-05 24.8 0.8 1.9e-05 24.2 0.8 1.2 1 0 0 1 1 1 1 E1-E2 ATPase MIP PF00230.20 OAG12533.1 - 1.6e-31 109.8 6.3 2.1e-31 109.4 6.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein CK_II_beta PF01214.18 OAG12534.1 - 2.2e-75 252.5 0.3 2.7e-75 252.2 0.3 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DpnI PF06044.12 OAG12534.1 - 0.09 12.4 0.1 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 Dam-replacing family PAS_9 PF13426.7 OAG12535.1 - 2.3e-14 53.5 0.0 7.6e-14 51.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OAG12535.1 - 0.059 13.4 0.0 0.51 10.4 0.0 2.5 3 0 0 3 3 3 0 PAS fold Abhydrolase_1 PF00561.20 OAG12536.1 - 1.7e-06 27.9 0.2 2.6e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG12536.1 - 9.1e-05 23.2 10.1 0.00016 22.4 10.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family CFEM PF05730.11 OAG12537.1 - 2.1e-14 53.3 9.7 3.6e-14 52.6 9.7 1.4 1 0 0 1 1 1 1 CFEM domain DUF719 PF05334.13 OAG12537.1 - 0.15 12.2 2.4 0.2 11.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) THEG4 PF15834.5 OAG12537.1 - 0.38 10.7 4.1 0.55 10.2 4.1 1.2 1 0 0 1 1 1 0 Testis highly expressed protein 4 Podoplanin PF05808.11 OAG12537.1 - 1.6 8.9 4.3 1.9 8.5 4.3 1.2 1 0 0 1 1 1 0 Podoplanin WD40 PF00400.32 OAG12538.1 - 3.7e-22 78.2 20.2 7.6e-06 26.6 0.2 7.0 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG12538.1 - 1.1e-12 48.1 7.6 1.4e-05 25.3 0.2 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 OAG12538.1 - 0.018 13.1 2.9 0.18 9.8 0.0 2.1 2 0 0 2 2 2 0 IKI3 family AdoHcyase PF05221.17 OAG12540.1 - 2.8e-126 420.7 0.0 1.9e-73 247.3 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OAG12540.1 - 9.4e-83 276.1 1.5 1.4e-82 275.6 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG12540.1 - 3e-06 26.7 0.1 7.3e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAG12540.1 - 0.0026 17.4 0.2 0.0044 16.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OAG12540.1 - 0.0051 17.1 0.1 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Oxidored_nitro PF00148.19 OAG12540.1 - 0.032 13.0 0.1 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 OAG12540.1 - 0.096 12.4 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ABC_tran PF00005.27 OAG12541.1 - 2.6e-45 154.3 0.9 2.1e-21 76.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAG12541.1 - 4.3e-19 68.3 8.4 4.3e-19 68.3 8.4 2.9 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 OAG12541.1 - 1.4e-12 48.1 14.0 0.0023 17.8 0.0 4.8 3 2 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG12541.1 - 2e-10 40.5 0.6 0.0087 15.5 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG12541.1 - 3.2e-07 31.1 12.5 0.01 16.4 0.0 4.8 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 OAG12541.1 - 4e-05 23.4 0.2 0.0029 17.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 OAG12541.1 - 4.5e-05 23.5 0.0 0.083 13.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG12541.1 - 5e-05 23.3 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OAG12541.1 - 7.5e-05 22.4 0.4 0.26 11.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG12541.1 - 9.8e-05 22.9 0.4 0.77 10.3 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 OAG12541.1 - 0.00026 21.1 0.1 0.99 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAG12541.1 - 0.00032 21.0 0.1 1.2 9.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OAG12541.1 - 0.00065 19.5 0.5 1.5 8.5 0.0 2.9 3 1 1 4 4 3 2 AAA domain AAA_16 PF13191.6 OAG12541.1 - 0.001 19.5 2.8 0.079 13.3 0.4 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_28 PF13521.6 OAG12541.1 - 0.0016 18.7 2.3 0.19 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OAG12541.1 - 0.0017 18.2 11.1 0.31 10.7 0.0 4.5 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.29 OAG12541.1 - 0.0067 16.9 0.0 3.8 7.9 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG12541.1 - 0.0072 16.2 0.2 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_27 PF13514.6 OAG12541.1 - 0.018 14.6 0.6 6.7 6.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 OAG12541.1 - 0.019 15.0 0.3 13 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAG12541.1 - 0.025 14.9 0.0 7.9 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.14 OAG12541.1 - 0.093 12.6 0.0 4.2 7.3 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 OAG12541.1 - 0.11 11.5 2.5 6.1 5.7 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 OAG12541.1 - 0.14 12.0 0.0 6.6 6.6 0.0 2.6 2 0 0 2 2 2 0 NTPase cobW PF02492.19 OAG12541.1 - 0.31 10.6 0.9 11 5.6 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 OAG12541.1 - 0.77 9.8 6.3 5.5 7.0 0.1 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain FlxA PF14282.6 OAG12541.1 - 1.8 8.6 3.8 0.66 10.0 0.4 2.0 2 0 0 2 2 1 0 FlxA-like protein SGL PF08450.12 OAG12543.1 - 9e-05 22.2 0.0 0.26 10.8 0.0 3.0 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SUKH-4 PF14435.6 OAG12543.1 - 0.038 14.0 0.1 0.75 9.8 0.1 2.2 2 0 0 2 2 2 0 SUKH-4 immunity protein SARAF PF06682.12 OAG12546.1 - 0.0012 18.5 2.1 0.0012 18.5 2.1 11.0 6 4 7 13 13 13 1 SOCE-associated regulatory factor of calcium homoeostasis YceD PF02620.17 OAG12547.1 - 0.047 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD SLD3 PF08639.10 OAG12548.1 - 2.1e-139 465.7 8.9 3e-139 465.2 8.9 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 DUF4746 PF15928.5 OAG12549.1 - 1 8.7 5.7 1.1 8.6 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mito_carr PF00153.27 OAG12551.1 - 1.8e-68 226.5 1.6 5.3e-25 87.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG12551.1 - 0.061 12.5 1.3 3.6 6.7 0.0 3.3 3 1 0 4 4 4 0 Gammaproteobacterial serine protease Tim17 PF02466.19 OAG12551.1 - 0.35 11.2 3.6 0.43 11.0 1.2 2.6 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family adh_short PF00106.25 OAG12552.1 - 8.7e-24 84.1 0.0 3.1e-23 82.3 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12552.1 - 2.6e-15 56.7 0.0 1.5e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12552.1 - 7.5e-10 39.0 0.2 3.9e-09 36.7 0.0 2.1 2 1 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 OAG12552.1 - 0.0021 17.4 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG12552.1 - 0.005 16.3 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAG12552.1 - 0.066 13.0 0.3 0.17 11.7 0.3 1.7 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 OAG12552.1 - 0.08 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OAG12552.1 - 0.083 12.8 1.2 0.49 10.3 0.3 2.4 2 1 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG12552.1 - 0.089 11.9 0.2 0.2 10.7 0.2 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain CoA_binding_2 PF13380.6 OAG12552.1 - 0.13 12.8 0.0 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain Sas10 PF09368.10 OAG12553.1 - 1.2e-27 96.1 7.8 1.2e-27 96.1 7.8 3.0 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OAG12553.1 - 1.2e-12 48.3 1.5 1.4e-11 44.9 0.0 2.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family MMgT PF10270.9 OAG12554.1 - 3.9e-29 100.9 0.0 5e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Ammonium_transp PF00909.21 OAG12557.1 - 3.5e-114 381.6 24.7 4e-114 381.4 24.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM107 PF14995.6 OAG12557.1 - 6 7.3 8.6 0.55 10.7 1.0 2.4 2 0 0 2 2 2 0 Transmembrane protein SpoV PF08183.11 OAG12557.1 - 9.9 6.2 6.2 0.96 9.4 0.5 2.3 2 0 0 2 2 2 0 Stage V sporulation protein family Staygreen PF12638.7 OAG12559.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Staygreen protein G10 PF01125.17 OAG12559.1 - 0.038 13.7 0.4 0.048 13.4 0.4 1.1 1 0 0 1 1 1 0 G10 protein Pkinase PF00069.25 OAG12560.1 - 8.5e-69 231.8 0.0 1.6e-68 230.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12560.1 - 7.6e-38 130.3 0.0 1.3e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG12560.1 - 4.7e-05 22.8 0.0 0.00013 21.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG12560.1 - 6.6e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG12560.1 - 0.0018 17.1 4.4 0.0018 17.1 0.0 2.7 4 0 0 4 4 4 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OAG12560.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 DivIVA PF05103.13 OAG12560.1 - 6.1 6.9 9.6 11 6.1 0.3 3.2 3 0 0 3 3 3 0 DivIVA protein tRNA-synt_His PF13393.6 OAG12561.1 - 4e-40 138.0 0.0 7e-33 114.2 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OAG12561.1 - 2.5e-11 43.6 0.0 5.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 OAG12561.1 - 0.0023 17.5 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 OAG12561.1 - 0.0037 16.4 0.3 0.018 14.2 0.3 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF5305 PF17231.2 OAG12562.1 - 0.036 13.4 0.1 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF2663 PF10864.8 OAG12562.1 - 0.08 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) CPDase PF07823.11 OAG12565.1 - 8.5e-27 94.1 0.0 1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein GLE1 PF07817.13 OAG12566.1 - 5.4e-23 81.5 0.0 1.2e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 GLE1-like protein Borrelia_P83 PF05262.11 OAG12566.1 - 0.095 11.2 21.3 0.14 10.7 21.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF572 PF04502.13 OAG12566.1 - 1.3 8.6 20.0 1.8 8.1 20.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PMC2NT PF08066.12 OAG12566.1 - 3.8 8.3 6.2 2.4 8.9 0.7 2.9 2 1 0 3 3 3 0 PMC2NT (NUC016) domain RNB PF00773.19 OAG12567.1 - 1.1e-86 291.1 0.1 1.9e-86 290.4 0.1 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 OAG12567.1 - 2.7e-26 91.4 0.0 7.5e-26 90.0 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 OAG12567.1 - 1.9e-25 89.0 0.0 5.2e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 OAG12567.1 - 6.7e-05 23.0 0.0 0.032 14.4 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 OAG12567.1 - 0.0023 17.7 1.0 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OAG12567.1 - 0.048 13.6 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 S1 domain Ferritin_2 PF13668.6 OAG12568.1 - 4.1e-41 140.4 3.2 6.8e-41 139.7 3.2 1.4 1 0 0 1 1 1 1 Ferritin-like domain MFS_1 PF07690.16 OAG12569.1 - 7.6e-24 84.3 49.1 1.4e-14 53.8 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.21 OAG12570.1 - 5.8e-119 397.8 30.6 6.6e-119 397.6 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG12570.1 - 8e-22 77.7 33.9 1.1e-21 77.2 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4131 PF13567.6 OAG12570.1 - 0.69 9.5 0.0 0.69 9.5 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 OAG12572.1 - 1e-32 113.6 0.0 1.8e-20 73.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12572.1 - 5.3e-16 58.7 0.0 1.2e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OAG12572.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG12572.1 - 0.2 11.0 0.0 1.2 8.3 0.0 2.2 3 0 0 3 3 3 0 Kinase-like Mito_carr PF00153.27 OAG12573.1 - 4.8e-50 167.4 2.1 1.1e-18 66.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3343 PF11823.8 OAG12573.1 - 0.046 13.2 0.0 0.16 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) HET PF06985.11 OAG12575.1 - 6.3e-13 49.3 9.4 8.8e-10 39.1 0.6 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 OAG12575.1 - 6e-10 38.7 0.0 1.4e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAG12575.1 - 8.4e-08 32.8 0.0 2.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OAG12575.1 - 2.1e-05 24.6 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_10 PF13374.6 OAG12575.1 - 0.0027 17.5 0.1 0.0078 16.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG12575.1 - 0.0075 16.5 0.2 0.025 14.9 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG12575.1 - 0.014 15.9 0.1 0.063 13.9 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_22 PF13401.6 OAG12575.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 OAG12575.1 - 0.045 13.6 0.2 0.16 11.9 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_14 PF13173.6 OAG12575.1 - 0.046 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG12575.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TPR_2 PF07719.17 OAG12575.1 - 0.25 11.5 2.1 0.43 10.8 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG12575.1 - 1.3 9.4 3.3 1.4 9.3 0.3 2.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Gryzun PF07919.12 OAG12577.1 - 1.9e-194 647.8 0.0 2.4e-194 647.5 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 OAG12577.1 - 1.9e-87 293.1 1.0 6.3e-82 275.1 1.9 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 RXT2_N PF08595.11 OAG12578.1 - 1.8e-28 99.6 0.2 1.8e-28 99.6 0.2 2.3 3 0 0 3 3 3 1 RXT2-like, N-terminal CAP_GLY PF01302.25 OAG12579.1 - 3.4e-19 68.6 0.2 6e-19 67.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 OAG12579.1 - 6.2e-07 29.6 10.3 0.074 13.5 2.4 4.9 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAG12579.1 - 7e-06 25.7 0.1 0.0084 15.6 0.5 2.9 3 0 0 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 OAG12579.1 - 3.2e-05 23.6 7.5 0.0085 15.8 1.3 4.8 3 1 2 5 5 5 3 Leucine rich repeat PTPRCAP PF15713.5 OAG12579.1 - 0.035 14.4 8.6 0.067 13.5 8.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RNA_pol_3_Rpc31 PF11705.8 OAG12579.1 - 0.04 14.2 4.9 0.065 13.5 4.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 OAG12579.1 - 0.086 12.5 3.5 0.18 11.5 3.5 1.5 1 0 0 1 1 1 0 FAM176 family LRR_6 PF13516.6 OAG12579.1 - 0.28 11.4 6.0 43 4.5 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat RPA43_OB PF17875.1 OAG12579.1 - 0.41 11.3 2.2 0.66 10.6 2.2 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Ribosomal_60s PF00428.19 OAG12579.1 - 0.47 11.1 10.0 1 10.0 10.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein GOLD_2 PF13897.6 OAG12579.1 - 0.85 10.1 5.5 1.5 9.3 5.5 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CENP-B_dimeris PF09026.10 OAG12579.1 - 2.6 8.5 16.6 4.9 7.6 16.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAG12579.1 - 2.7 6.0 13.3 3.9 5.5 13.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OAG12579.1 - 5.2 5.2 8.4 7.5 4.7 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SF3A2 PF16835.5 OAG12580.1 - 3.4e-34 117.1 0.2 5.9e-34 116.3 0.1 1.5 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OAG12580.1 - 2e-05 24.8 0.5 2e-05 24.8 0.5 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 OAG12580.1 - 0.043 13.4 1.5 0.11 12.1 1.5 1.7 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CRC_subunit PF08624.10 OAG12582.1 - 4.2e-52 176.2 0.0 6e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Zn_clus PF00172.18 OAG12583.1 - 6.2e-09 35.8 7.7 9.5e-09 35.2 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG12583.1 - 8.8e-05 21.5 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain G-patch PF01585.23 OAG12584.1 - 1.2e-06 28.3 1.0 2e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 G-patch domain adh_short PF00106.25 OAG12585.1 - 6.5e-15 55.1 0.0 1.9e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12585.1 - 8.3e-06 25.5 0.0 4.9e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12585.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG12585.1 - 0.0002 20.9 0.0 0.0005 19.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_hydro_15 PF00723.21 OAG12585.1 - 0.019 13.8 0.1 0.024 13.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 LIM PF00412.22 OAG12586.1 - 1.7e-24 85.8 33.8 9.5e-10 38.6 4.4 3.8 4 0 0 4 4 4 3 LIM domain Prefoldin PF02996.17 OAG12587.1 - 3e-25 88.5 0.0 4.2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OAG12587.1 - 0.00087 19.2 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit Fib_alpha PF08702.10 OAG12587.1 - 0.016 15.4 0.2 7 6.8 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HR1 PF02185.16 OAG12587.1 - 0.025 14.7 0.4 1.5 9.0 0.0 2.7 2 1 0 2 2 2 0 Hr1 repeat FlaC_arch PF05377.11 OAG12587.1 - 0.03 14.7 0.2 0.95 9.9 0.0 2.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 OAG12587.1 - 0.036 14.4 0.5 7.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Uds1 PF15456.6 OAG12587.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 Up-regulated During Septation SHE3 PF17078.5 OAG12587.1 - 0.09 12.5 0.7 8.2 6.1 0.0 2.1 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 PHM7_cyt PF14703.6 OAG12587.1 - 0.098 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Cupin_8 PF13621.6 OAG12588.1 - 6.5e-27 94.8 0.0 8.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAG12588.1 - 0.015 14.7 0.0 0.064 12.7 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein JmjC PF02373.22 OAG12588.1 - 0.083 13.3 0.0 0.28 11.6 0.0 1.8 1 1 0 1 1 1 0 JmjC domain, hydroxylase SKA1 PF07160.12 OAG12589.1 - 0.0047 16.8 4.4 0.006 16.5 4.4 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 ATG16 PF08614.11 OAG12589.1 - 0.0052 17.0 7.4 0.0076 16.5 7.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 OAG12589.1 - 0.0086 15.7 7.0 0.011 15.4 7.0 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Fib_alpha PF08702.10 OAG12589.1 - 0.015 15.5 7.0 0.024 14.8 7.0 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NYD-SP28 PF14772.6 OAG12589.1 - 0.016 15.2 2.5 0.016 15.2 2.5 1.6 2 0 0 2 2 2 0 Sperm tail Glyco_H_20C_C PF18088.1 OAG12589.1 - 0.02 14.7 2.8 0.026 14.4 2.8 1.1 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain RmuC PF02646.16 OAG12589.1 - 0.021 14.0 6.0 0.035 13.3 6.0 1.3 1 0 0 1 1 1 0 RmuC family CdvA PF18822.1 OAG12589.1 - 0.029 14.2 2.6 0.038 13.8 1.9 1.5 1 1 0 1 1 1 0 CdvA-like coiled-coil domain DUF4407 PF14362.6 OAG12589.1 - 0.032 13.6 4.0 0.036 13.4 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 OAG12589.1 - 0.035 13.4 1.4 0.042 13.2 1.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4472 PF14739.6 OAG12589.1 - 0.035 14.8 4.5 0.062 14.0 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Apt1 PF10351.9 OAG12589.1 - 0.04 12.8 3.4 0.049 12.5 3.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5595 PF18077.1 OAG12589.1 - 0.058 13.5 0.8 0.11 12.6 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) YlqD PF11068.8 OAG12589.1 - 0.06 13.7 7.2 0.093 13.1 7.2 1.3 1 0 0 1 1 1 0 YlqD protein DUF3573 PF12097.8 OAG12589.1 - 0.073 11.9 1.9 0.092 11.6 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Bacillus_HBL PF05791.11 OAG12589.1 - 0.085 12.7 6.2 0.12 12.2 6.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Lipoprotein_6 PF01441.19 OAG12589.1 - 0.086 12.8 0.3 0.15 12.1 0.3 1.4 1 1 0 1 1 1 0 Lipoprotein FPP PF05911.11 OAG12589.1 - 0.087 11.0 7.6 0.11 10.7 7.6 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Lebercilin PF15619.6 OAG12589.1 - 0.091 12.4 9.3 0.42 10.2 9.6 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 OAG12589.1 - 0.21 10.9 10.6 0.49 9.7 10.6 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 OAG12589.1 - 0.29 11.2 3.4 0.64 10.1 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 OAG12589.1 - 0.31 11.7 4.4 0.51 11.0 4.4 1.4 1 0 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 OAG12589.1 - 0.34 8.8 3.5 0.39 8.6 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CREPT PF16566.5 OAG12589.1 - 0.42 10.8 5.9 0.42 10.8 4.8 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2937 PF11157.8 OAG12589.1 - 0.74 9.5 4.0 1.3 8.7 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) DUF948 PF06103.11 OAG12589.1 - 0.85 9.9 2.8 1.1 9.5 0.8 2.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 OAG12589.1 - 0.89 9.9 9.9 1.2 9.4 9.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 OAG12589.1 - 1.1 9.1 7.7 0.5 10.2 3.1 2.4 1 1 1 2 2 2 0 Septum formation initiator SlyX PF04102.12 OAG12589.1 - 1.3 9.7 9.1 1.7 9.3 6.0 2.4 1 1 1 2 2 2 0 SlyX FOXP-CC PF16159.5 OAG12589.1 - 8.2 7.1 7.5 10 6.9 2.4 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain p450 PF00067.22 OAG12594.1 - 1.2e-70 238.6 0.0 1.5e-70 238.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAG12596.1 - 7e-75 252.4 0.0 9.4e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG12596.1 - 6.5e-40 136.9 0.0 1.5e-39 135.7 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 OAG12596.1 - 0.0011 18.6 0.0 0.06 12.9 0.0 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG12596.1 - 0.0019 18.7 0.0 0.0053 17.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG12596.1 - 0.0033 16.7 0.0 0.024 13.9 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG12596.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG12596.1 - 0.037 12.7 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 OAG12596.1 - 0.051 12.6 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 OAG12596.1 - 0.051 13.1 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 OAG12596.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.18 OAG12596.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Rox3 PF08633.10 OAG12597.1 - 5.6e-53 180.3 0.2 9.1e-53 179.6 0.2 1.3 1 0 0 1 1 1 1 Rox3 mediator complex subunit Rad10 PF03834.14 OAG12598.1 - 1.8e-48 163.3 0.1 2.5e-48 162.8 0.1 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OAG12598.1 - 0.0011 19.5 0.0 0.0021 18.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain SPATA3 PF15662.5 OAG12598.1 - 2.6 8.6 8.2 0.29 11.7 2.8 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family F-box PF00646.33 OAG12599.1 - 1.5e-05 24.7 0.1 0.00036 20.3 0.0 3.0 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OAG12599.1 - 0.0027 17.6 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like GIY-YIG PF01541.24 OAG12601.1 - 0.0056 16.9 0.4 0.013 15.8 0.4 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain Apq12 PF12716.7 OAG12602.1 - 1.9e-12 46.9 12.5 3e-12 46.3 12.5 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis EphA2_TM PF14575.6 OAG12604.1 - 0.083 13.8 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.6 OAG12604.1 - 0.14 12.6 0.8 0.23 11.9 0.3 1.6 1 1 0 1 1 1 0 SCIMP protein CoatB PF10389.9 OAG12604.1 - 0.15 12.0 0.5 0.25 11.2 0.5 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B IU_nuc_hydro PF01156.19 OAG12606.1 - 1.3e-12 47.9 0.0 1.9e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase V-ATPase_H_N PF03224.14 OAG12608.1 - 9.1e-77 258.4 0.8 1.2e-76 258.1 0.8 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OAG12608.1 - 1.4e-35 121.9 0.2 1.6e-34 118.5 0.0 2.7 4 0 0 4 4 4 1 V-ATPase subunit H TIP120 PF08623.10 OAG12608.1 - 0.19 11.5 0.8 7 6.4 0.1 2.7 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) RNB PF00773.19 OAG12609.1 - 4.3e-98 328.7 0.1 6.4e-98 328.1 0.1 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 OAG12609.1 - 1.1e-30 105.4 2.6 1.7e-30 104.8 1.1 2.1 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 OAG12609.1 - 6.5e-30 103.8 0.1 1.7e-29 102.4 0.1 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 OAG12609.1 - 3.5e-21 75.0 0.0 1.1e-20 73.4 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 OAG12609.1 - 1.3e-09 38.1 0.1 4.1e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 Cold shock domain PIN_4 PF13638.6 OAG12609.1 - 5.8e-09 36.3 0.5 5.3e-08 33.2 0.2 2.6 2 0 0 2 2 2 1 PIN domain Dis3l2_C_term PF17877.1 OAG12609.1 - 0.0002 21.6 0.5 0.00067 19.9 0.1 2.2 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal Trypsin_2 PF13365.6 OAG12610.1 - 9.1e-30 104.5 0.9 1.4e-29 104.0 0.9 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OAG12610.1 - 0.0054 16.6 1.8 0.013 15.3 1.8 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 OAG12610.1 - 0.0054 15.4 0.4 0.025 13.3 0.1 1.9 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S32 PF05579.13 OAG12610.1 - 0.074 12.2 3.2 0.26 10.4 0.2 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 WH2 PF02205.20 OAG12612.1 - 2.3e-10 40.0 0.7 6.6e-10 38.5 0.7 1.9 1 0 0 1 1 1 1 WH2 motif Rhomboid PF01694.22 OAG12613.1 - 3.5e-14 53.1 11.7 7.8e-14 51.9 11.7 1.5 1 0 0 1 1 1 1 Rhomboid family CPBP PF02517.16 OAG12613.1 - 0.0051 17.2 6.1 0.59 10.5 0.4 2.3 2 0 0 2 2 2 2 CPBP intramembrane metalloprotease Imm51 PF15595.6 OAG12614.1 - 0.0055 16.6 0.4 0.0084 16.0 0.4 1.3 1 0 0 1 1 1 1 Immunity protein 51 BLYB PF05289.11 OAG12614.1 - 0.007 16.6 0.8 0.0086 16.3 0.8 1.1 1 0 0 1 1 1 1 Borrelia hemolysin accessory protein Dynamitin PF04912.14 OAG12614.1 - 0.0079 15.6 2.9 0.01 15.2 2.9 1.1 1 0 0 1 1 1 1 Dynamitin DUF4618 PF15397.6 OAG12614.1 - 0.03 13.8 3.7 0.13 11.7 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1192 PF06698.11 OAG12614.1 - 0.41 10.7 5.6 0.94 9.6 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) SlyX PF04102.12 OAG12614.1 - 0.43 11.2 3.3 2.9 8.6 2.8 2.0 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 OAG12614.1 - 0.84 9.5 6.4 0.31 10.8 2.3 1.9 1 1 1 2 2 2 0 Septum formation initiator DDHD PF02862.17 OAG12615.1 - 3.4e-26 92.8 0.0 2.3e-15 57.4 0.0 2.5 1 1 1 2 2 2 2 DDHD domain Aldedh PF00171.22 OAG12616.1 - 1e-185 617.7 0.7 1.2e-185 617.5 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG12616.1 - 0.021 14.3 0.1 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RRM_1 PF00076.22 OAG12617.1 - 8.9e-11 41.5 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAG12617.1 - 5.2e-09 36.5 16.6 1.4e-08 35.1 6.2 2.7 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 Pns11_12 PF17464.2 OAG12617.1 - 0.08 12.6 1.6 0.14 11.8 1.6 1.4 1 0 0 1 1 1 0 Non-structural protein 11 and 12 RRM_occluded PF16842.5 OAG12617.1 - 0.09 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif FXMRP1_C_core PF12235.8 OAG12617.1 - 0.21 12.2 12.9 0.18 12.4 4.5 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal PRR20 PF15708.5 OAG12617.1 - 0.95 9.3 12.9 0.022 14.7 4.0 2.1 2 0 0 2 2 2 0 Proline-rich protein family 20 Clathrin PF00637.20 OAG12619.1 - 3.1e-21 75.8 2.0 2.7e-19 69.4 1.8 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 OAG12619.1 - 2e-20 72.7 0.1 5.8e-20 71.3 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 OAG12619.1 - 4.4e-07 29.8 7.4 9.3e-07 28.8 7.4 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 OAG12619.1 - 1.5e-05 24.7 7.0 3.1e-05 23.7 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG12619.1 - 0.00012 21.9 3.6 0.00024 21.0 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG12619.1 - 0.00072 19.5 4.0 0.0018 18.3 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger TPR_14 PF13428.6 OAG12619.1 - 0.00089 19.9 0.2 4.7 8.3 0.0 3.8 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 OAG12619.1 - 0.00091 19.5 6.7 0.0017 18.6 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG12619.1 - 0.0013 18.7 1.5 0.0034 17.4 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG12619.1 - 0.0029 17.9 3.6 0.006 16.9 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain TPR_11 PF13414.6 OAG12619.1 - 0.0098 15.6 1.8 0.015 15.0 0.5 2.0 2 0 0 2 2 1 1 TPR repeat zf-C3HC4 PF00097.25 OAG12619.1 - 0.016 15.1 5.0 0.03 14.2 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 OAG12619.1 - 0.19 11.9 3.7 0.42 10.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 OAG12619.1 - 0.24 11.6 6.0 0.5 10.6 6.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OAG12619.1 - 0.26 11.2 4.0 0.59 10.0 4.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 OAG12619.1 - 0.61 10.0 5.5 1.2 9.0 5.5 1.6 1 0 0 1 1 1 0 PHD-finger ANAPC3 PF12895.7 OAG12619.1 - 1.3 9.3 4.8 20 5.5 0.3 3.3 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 KIP1 PF07765.12 OAG12619.1 - 2.3 8.4 4.7 0.56 10.4 0.8 2.0 2 0 0 2 2 1 0 KIP1-like protein zf-RING_11 PF17123.5 OAG12619.1 - 3.3 7.5 4.6 8.9 6.2 4.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger TPR_16 PF13432.6 OAG12619.1 - 3.3 8.4 5.8 2.9 8.6 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG12619.1 - 7.4 7.1 5.9 3.8 8.0 0.6 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat UPF0020 PF01170.18 OAG12620.1 - 1.1e-08 35.0 0.6 1.5e-06 28.0 0.6 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Redoxin PF08534.10 OAG12621.1 - 1.1e-32 112.8 0.0 1.2e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG12621.1 - 2.9e-08 33.7 0.0 3.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF3975 PF13126.6 OAG12622.1 - 1.5 9.3 5.9 1.9 9.0 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3975) WASH-7_N PF14745.6 OAG12623.1 - 0.055 12.0 0.0 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal CorA PF01544.18 OAG12623.1 - 0.065 12.5 1.5 4.8 6.4 1.5 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Ribonucleas_3_3 PF14622.6 OAG12624.1 - 1.3e-06 28.6 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG12624.1 - 0.0014 19.2 0.1 0.023 15.3 0.1 2.8 2 1 0 2 2 2 1 Ribonuclease III domain Glyco_hydro_17 PF00332.18 OAG12625.1 - 1.3e-29 103.8 1.5 1.6e-28 100.3 1.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DapH_N PF08503.10 OAG12625.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Glyco_hydro_47 PF01532.20 OAG12626.1 - 1.5e-162 541.6 0.1 1.8e-162 541.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MFS_1 PF07690.16 OAG12627.1 - 2.4e-37 128.7 48.9 2.8e-37 128.4 43.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2613 PF11021.8 OAG12627.1 - 0.079 13.1 0.7 23 5.2 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Aldedh PF00171.22 OAG12628.1 - 1e-108 363.8 0.0 1.3e-108 363.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GD_AH_C PF04295.13 OAG12628.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus GN3L_Grn1 PF08701.11 OAG12629.1 - 1.8e-23 82.4 15.2 1.8e-23 82.4 15.2 2.3 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 OAG12629.1 - 3.3e-17 62.6 1.6 7.5e-13 48.6 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG12629.1 - 1.6e-06 28.1 0.5 4.7e-05 23.4 0.5 2.2 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 OAG12629.1 - 3.7e-05 23.4 0.0 0.04 13.4 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OAG12629.1 - 5.2e-05 22.8 0.4 0.00031 20.3 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG12629.1 - 0.00011 22.4 8.8 0.18 11.8 3.0 3.9 2 2 1 3 3 3 2 Dynamin family Arf PF00025.21 OAG12629.1 - 0.0041 16.6 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family MeaB PF03308.16 OAG12629.1 - 0.03 13.3 0.1 0.03 13.3 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 OAG12629.1 - 0.031 14.5 0.4 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG12629.1 - 0.049 13.1 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 OAG12629.1 - 0.074 13.6 3.3 0.21 12.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 OAG12629.1 - 0.12 11.9 0.6 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 OAG12629.1 - 0.47 11.0 2.3 0.53 10.8 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 OAG12629.1 - 0.6 10.6 0.1 0.6 10.6 0.1 2.8 2 1 0 2 2 1 0 AAA domain HAD_2 PF13419.6 OAG12630.1 - 1e-18 68.0 0.0 2e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG12630.1 - 1.8e-06 28.4 0.0 4.4e-05 23.9 0.0 2.6 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 OAG12630.1 - 0.018 15.0 0.3 0.05 13.6 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HAD PF12710.7 OAG12630.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 OAG12632.1 - 6.3e-14 51.6 0.4 1.5e-13 50.4 0.4 1.6 1 0 0 1 1 1 1 Homeodomain CCDC14 PF15254.6 OAG12632.1 - 0.28 9.8 4.8 0.42 9.2 4.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Promethin PF16015.5 OAG12633.1 - 0.12 12.4 0.3 0.15 12.0 0.3 1.1 1 0 0 1 1 1 0 Promethin Peptidase_M24 PF00557.24 OAG12634.1 - 1e-55 188.7 0.1 1.3e-55 188.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAG12634.1 - 3.4e-22 78.5 0.0 5.9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pre-SET PF05033.16 OAG12634.1 - 0.13 12.9 5.2 0.3 11.7 5.2 1.6 1 0 0 1 1 1 0 Pre-SET motif PPR_2 PF13041.6 OAG12635.1 - 6.6e-44 147.9 8.0 9.9e-09 35.3 0.0 13.5 11 4 4 15 15 15 9 PPR repeat family PPR_3 PF13812.6 OAG12635.1 - 5.2e-37 125.8 0.0 0.0014 18.7 0.0 11.6 9 4 3 13 13 13 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAG12635.1 - 3e-21 74.8 2.5 1.3e-06 28.0 0.0 10.3 13 0 0 13 13 13 4 PPR repeat PPR_long PF17177.4 OAG12635.1 - 6e-20 71.5 8.5 1.7e-07 30.8 0.0 6.4 4 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OAG12635.1 - 6.4e-19 66.8 25.8 0.001 19.1 0.1 13.3 16 0 0 16 16 16 5 PPR repeat RPM2 PF08579.11 OAG12635.1 - 1.3e-06 28.7 0.0 4.3e-05 23.9 0.0 2.9 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 OAG12635.1 - 0.018 14.1 0.4 1.3 8.1 0.0 3.8 5 0 0 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 OAG12635.1 - 0.062 13.4 0.9 31 4.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 OAG12636.1 - 5e-16 58.7 1.0 1.1e-15 57.7 1.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG12636.1 - 5.7e-09 36.2 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Ribosomal_L29 PF00831.23 OAG12637.1 - 9.2e-18 64.0 5.1 1.2e-17 63.6 0.3 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein DUF3256 PF11644.8 OAG12637.1 - 0.044 13.3 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) V-SNARE_C PF12352.8 OAG12638.1 - 2.2e-14 53.5 0.3 2.2e-14 53.5 0.3 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.11 OAG12638.1 - 0.02 15.5 1.1 0.02 15.5 1.1 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 OAG12638.1 - 0.065 12.1 5.8 0.1 11.5 5.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Vps54_N PF10475.9 OAG12638.1 - 0.097 11.9 1.4 0.19 11.0 1.0 1.5 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF4570 PF15134.6 OAG12638.1 - 0.12 12.4 3.3 0.21 11.6 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) CHDCT2 PF08074.11 OAG12638.1 - 0.25 11.5 3.3 0.27 11.4 1.8 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain GLTSCR1 PF15249.6 OAG12638.1 - 0.25 11.8 2.7 0.29 11.6 0.6 1.9 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein ATP-synt_10 PF05176.14 OAG12639.1 - 1.8e-75 253.5 0.0 2.1e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Nefa_Nip30_N PF10187.9 OAG12646.1 - 3.9e-32 110.7 12.9 3.9e-32 110.7 12.9 2.0 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 TMEM173 PF15009.6 OAG12646.1 - 0.0096 15.1 0.3 0.012 14.8 0.3 1.2 1 0 0 1 1 1 1 Transmembrane protein 173 Aldo_ket_red PF00248.21 OAG12647.1 - 1.8e-52 178.4 0.0 9.1e-51 172.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NAD_binding_8 PF13450.6 OAG12648.1 - 5.6e-10 39.3 0.1 1.4e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG12648.1 - 2.3e-08 33.6 0.8 1.1e-07 31.4 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAG12648.1 - 1.4e-07 31.2 0.1 2.3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG12648.1 - 3.3e-07 29.9 0.0 7e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAG12648.1 - 5.6e-07 28.6 0.3 8.8e-07 28.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG12648.1 - 0.00011 21.5 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG12648.1 - 0.00021 20.7 0.1 0.00037 19.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG12648.1 - 0.00038 19.8 0.0 0.00066 19.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG12648.1 - 0.00093 18.9 0.2 0.0035 17.0 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG12648.1 - 0.0025 17.1 0.3 0.004 16.4 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG12648.1 - 0.0027 18.2 0.1 0.0065 17.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG12648.1 - 0.0055 15.8 0.0 0.0082 15.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A IlvN PF07991.12 OAG12648.1 - 0.041 13.5 0.2 0.074 12.6 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 OAG12648.1 - 0.22 11.2 0.2 0.39 10.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Band_7 PF01145.25 OAG12649.1 - 9.9e-30 103.9 0.4 9.9e-30 103.9 0.4 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 OAG12649.1 - 8.5e-24 83.4 2.7 8.5e-24 83.4 2.7 2.2 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 OAG12649.1 - 0.02 14.2 0.8 0.044 13.1 0.8 1.6 1 1 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 OAG12649.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Abhydrolase_3 PF07859.13 OAG12650.1 - 1.2e-05 25.3 0.3 0.00069 19.5 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG12650.1 - 0.00016 22.3 0.3 0.00027 21.6 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG12650.1 - 0.00033 20.4 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG12650.1 - 0.041 13.2 0.0 0.12 11.6 0.0 1.7 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 OAG12650.1 - 0.063 12.1 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Steryl acetyl hydrolase FAD_binding_3 PF01494.19 OAG12655.1 - 1e-15 57.8 0.0 6.2e-10 38.8 0.0 2.9 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 OAG12655.1 - 0.084 13.1 0.0 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAG12655.1 - 0.16 11.0 0.0 0.74 8.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Peptidase_S8 PF00082.22 OAG12656.1 - 9.5e-25 87.5 5.0 1.3e-24 87.0 5.0 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG12656.1 - 1e-07 32.5 0.8 1.7e-07 31.8 0.3 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 Peroxidase_2 PF01328.17 OAG12657.1 - 1.9e-48 165.5 0.0 2.5e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Kp4 PF09044.10 OAG12659.1 - 2.7e-25 88.8 2.9 3.5e-25 88.5 2.9 1.1 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 OAG12659.1 - 3.8e-07 30.8 4.0 5.5e-07 30.3 4.0 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family PASTA PF03793.19 OAG12659.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 PASTA domain Fungal_trans PF04082.18 OAG12660.1 - 2.5e-21 75.9 0.1 3.4e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG12661.1 - 3.6e-38 131.4 22.6 3.6e-38 131.4 22.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAG12661.1 - 0.0094 14.3 0.8 0.017 13.5 0.8 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PRT_C PF08372.10 OAG12661.1 - 0.013 15.3 0.3 0.027 14.2 0.3 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal HpcH_HpaI PF03328.14 OAG12662.1 - 2.8e-32 111.6 0.8 3.7e-32 111.3 0.8 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 OAG12662.1 - 0.03 13.4 0.1 0.18 10.9 0.1 2.0 1 1 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Ribonuc_L-PSP PF01042.21 OAG12663.1 - 5.2e-23 81.3 0.0 6.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF5130 PF17174.4 OAG12663.1 - 0.074 13.3 0.0 0.084 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) 2OG-FeII_Oxy PF03171.20 OAG12664.1 - 1.5e-12 47.9 0.0 2.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG12664.1 - 4.9e-09 37.0 0.0 1.2e-08 35.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ORC6 PF05460.13 OAG12665.1 - 8.1e-35 120.7 10.2 4.5e-29 101.8 10.9 2.5 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Cytomega_UL20A PF05984.12 OAG12665.1 - 0.29 11.5 0.2 0.29 11.5 0.2 2.6 3 0 0 3 3 3 0 Cytomegalovirus UL20A protein DUF3328 PF11807.8 OAG12666.1 - 1.8e-44 152.1 0.1 2.3e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SET PF00856.28 OAG12668.1 - 2.4e-06 28.0 0.1 5.7e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 SET domain SET PF00856.28 OAG12669.1 - 1.3e-08 35.4 0.0 2.4e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 SET domain DDE_Tnp_1_4 PF13701.6 OAG12669.1 - 0.21 9.8 0.0 0.29 9.3 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 KH_8 PF17903.1 OAG12670.1 - 1.4e-28 98.8 0.3 3.3e-28 97.6 0.0 1.9 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 OAG12670.1 - 0.001 18.8 0.1 0.46 10.3 0.0 2.9 3 0 0 3 3 3 2 KH domain adh_short PF00106.25 OAG12671.1 - 4.5e-23 81.7 0.0 6e-22 78.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12671.1 - 2.8e-16 59.8 0.0 1.9e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG12671.1 - 0.00027 20.5 0.0 0.00052 19.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG12671.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG12671.1 - 0.083 12.7 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Kin17_mid PF10357.9 OAG12672.1 - 4.9e-44 149.3 0.7 4.9e-44 149.3 0.7 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 OAG12672.1 - 0.00069 19.9 2.8 0.0015 18.8 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAG12672.1 - 0.021 15.1 3.2 0.031 14.6 0.7 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAG12672.1 - 0.022 15.0 1.4 0.061 13.6 1.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Presenilin PF01080.17 OAG12672.1 - 3.4 6.3 6.0 4.3 6.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 OAG12672.1 - 8.5 5.1 8.4 4.3 6.1 5.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Polysacc_lyase PF14099.6 OAG12673.1 - 5.1e-40 137.6 9.5 5.9e-40 137.4 9.5 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Porin_3 PF01459.22 OAG12673.1 - 0.067 12.7 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic porin Toxin_YhaV PF11663.8 OAG12673.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system Cupin_5 PF06172.11 OAG12674.1 - 3.2e-44 150.5 0.0 3.7e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) SYF2 PF08231.12 OAG12676.1 - 4.7e-45 153.9 12.3 4.7e-45 153.9 12.3 1.5 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.14 OAG12676.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.6 1 1 1 2 2 2 0 ARD/ARD' family RRM_1 PF00076.22 OAG12677.1 - 0.012 15.4 0.0 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MWFE PF15879.5 OAG12677.1 - 0.13 12.4 1.8 0.31 11.3 0.0 2.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit RRN3 PF05327.11 OAG12677.1 - 9 4.7 10.1 0.077 11.5 2.3 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CWC25 PF12542.8 OAG12678.1 - 4.1e-20 72.6 0.1 4.1e-20 72.6 0.1 4.3 2 1 2 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 OAG12678.1 - 3.3e-13 49.6 15.9 3.3e-13 49.6 15.9 5.6 4 3 2 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Glyco_hydro_59 PF02057.15 OAG12679.1 - 3.1e-19 69.3 0.1 4.9e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 OAG12679.1 - 1.4e-12 47.9 0.4 3.4e-09 36.8 0.0 2.3 1 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 OAG12679.1 - 5.8e-10 38.7 0.2 2.2e-09 36.7 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OAG12679.1 - 9.1e-10 38.6 2.8 2.6e-09 37.2 2.8 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Protocadherin PF08374.11 OAG12680.1 - 0.11 12.5 2.7 0.24 11.4 2.7 1.5 1 0 0 1 1 1 0 Protocadherin US30 PF17624.2 OAG12680.1 - 0.26 10.3 0.7 0.69 8.9 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function Prefoldin_2 PF01920.20 OAG12682.1 - 2.1e-16 59.8 8.4 3.8e-16 58.9 8.4 1.4 1 1 0 1 1 1 1 Prefoldin subunit RasGAP_C PF03836.15 OAG12682.1 - 0.0031 17.7 5.8 0.024 14.8 0.5 2.2 2 1 0 2 2 2 2 RasGAP C-terminus Nmad5 PF18757.1 OAG12682.1 - 0.0063 16.7 0.8 0.0078 16.4 0.8 1.1 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 Emaravirus_P4 PF16505.5 OAG12682.1 - 0.086 11.9 0.3 0.13 11.3 0.2 1.3 1 1 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily DUF4200 PF13863.6 OAG12682.1 - 0.088 13.2 10.9 0.19 12.2 10.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 OAG12682.1 - 0.21 11.6 9.8 0.52 10.3 0.9 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JAKMIP_CC3 PF16034.5 OAG12682.1 - 6.1 6.7 12.4 79 3.1 12.4 2.0 1 1 0 1 1 1 0 JAKMIP CC3 domain Ceramidase PF05875.12 OAG12683.1 - 3.8e-101 338.0 17.0 4.4e-101 337.7 17.0 1.0 1 0 0 1 1 1 1 Ceramidase DUF2070 PF09843.9 OAG12683.1 - 0.017 13.4 5.6 0.022 13.1 5.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tubulin PF00091.25 OAG12684.1 - 1.3e-68 231.1 0.0 3.5e-68 229.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG12684.1 - 8.7e-43 145.5 0.1 1.4e-42 144.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAG12684.1 - 9.3e-05 22.7 0.0 0.00028 21.2 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OAG12684.1 - 0.0029 16.9 0.0 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 OAG12684.1 - 0.003 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain PEMT PF04191.13 OAG12685.1 - 1.3e-31 109.1 0.6 1.3e-31 109.1 0.6 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Aa_trans PF01490.18 OAG12686.1 - 6e-23 81.2 35.7 7.1e-23 81.0 35.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 OAG12687.1 - 1.5e-15 57.3 0.0 3.6e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12687.1 - 5.6e-09 35.7 0.0 1.3e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.19 OAG12688.1 - 2.4e-33 115.9 0.0 3.1e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HMG_box PF00505.19 OAG12689.1 - 8.2e-07 29.4 5.2 0.00014 22.2 0.1 3.4 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG12689.1 - 3.3e-05 24.4 15.1 3.4e-05 24.3 0.4 3.0 3 0 0 3 3 3 2 HMG-box domain PmbA_TldD PF01523.16 OAG12689.1 - 0.08 12.8 5.3 0.14 12.0 5.3 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Dicty_REP PF05086.12 OAG12689.1 - 2.4 6.0 7.2 2.9 5.8 7.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Adaptin_binding PF10199.9 OAG12689.1 - 5.6 7.6 10.4 1.1 9.8 6.4 1.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 G_glu_transpept PF01019.21 OAG12690.1 - 1.5e-152 509.0 0.0 2.8e-148 494.9 0.0 2.0 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase 7tm_6 PF02949.20 OAG12691.1 - 0.0043 16.2 2.2 0.0047 16.0 2.2 1.2 1 0 0 1 1 1 1 7tm Odorant receptor Kelch_5 PF13854.6 OAG12692.1 - 0.00041 20.3 1.8 2 8.5 0.1 4.2 5 0 0 5 5 5 2 Kelch motif DUF1180 PF06679.12 OAG12692.1 - 0.37 11.2 1.7 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CxC5 PF18718.1 OAG12693.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases HpcH_HpaI PF03328.14 OAG12694.1 - 6.2e-32 110.5 0.0 7.9e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TMP-TENI PF02581.17 OAG12694.1 - 0.019 14.3 0.3 0.32 10.3 0.1 2.5 2 1 0 2 2 2 0 Thiamine monophosphate synthase PEP-utilizers_C PF02896.18 OAG12694.1 - 0.11 11.6 0.0 0.46 9.6 0.0 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain DUF836 PF05768.14 OAG12695.1 - 1.1e-15 57.8 0.0 1.3e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 OAG12695.1 - 0.013 15.7 0.1 0.027 14.7 0.0 1.7 2 1 0 2 2 2 0 Glutaredoxin TraF PF13728.6 OAG12695.1 - 0.045 13.6 0.0 0.092 12.6 0.0 1.5 1 1 0 1 1 1 0 F plasmid transfer operon protein HCMVantigenic_N PF12154.8 OAG12695.1 - 0.083 13.0 0.6 0.14 12.2 0.6 1.4 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV CHORD PF04968.12 OAG12696.1 - 6e-51 171.0 22.3 1.6e-26 92.8 7.9 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.16 OAG12696.1 - 3.8e-11 43.9 0.1 6.1e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 OAG12696.1 - 2.4 8.1 12.5 7.7 6.4 1.1 3.3 2 1 0 2 2 2 0 BTK motif DUF4106 PF13388.6 OAG12696.1 - 5.5 6.1 6.7 7.5 5.7 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Thr_synth_N PF14821.6 OAG12697.1 - 2.1e-29 101.5 0.0 1.4e-28 98.9 0.0 2.4 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 OAG12697.1 - 1.5e-20 73.8 0.0 1.5e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acetyltransf_9 PF13527.7 OAG12698.1 - 0.0015 18.6 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG12698.1 - 0.0064 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG12698.1 - 0.055 13.4 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG12698.1 - 0.13 12.5 0.0 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family IBR PF01485.21 OAG12700.1 - 0.00018 21.7 8.7 0.00018 21.7 8.7 3.4 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain HORMA PF02301.18 OAG12701.1 - 7.1e-10 38.8 0.0 9.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.19 OAG12702.1 - 1.4e-13 50.5 1.9 1.1e-12 47.7 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAG12702.1 - 7.8e-07 29.3 0.3 0.006 16.7 0.0 3.2 2 0 0 2 2 2 2 Exportin 1-like protein RIX1 PF08167.12 OAG12702.1 - 4.7e-05 23.2 0.3 0.00029 20.6 0.0 2.5 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.15 OAG12702.1 - 0.002 16.7 0.1 0.0086 14.6 0.0 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Arm PF00514.23 OAG12702.1 - 0.058 13.5 1.0 0.18 11.9 0.0 2.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAG12702.1 - 0.067 13.7 2.1 0.53 10.8 0.2 3.7 4 0 0 4 4 4 0 HEAT-like repeat TPR_21 PF09976.9 OAG12702.1 - 0.084 12.6 0.6 0.26 11.0 0.6 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain S-methyl_trans PF02574.16 OAG12703.1 - 4.2e-52 177.6 0.0 5e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Arrestin_C PF02752.22 OAG12706.1 - 2.8e-13 50.5 0.0 1.2e-12 48.4 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 OAG12707.1 - 1.5e-51 174.8 0.0 1.7e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-ZPR1 PF03367.13 OAG12708.1 - 2.2e-108 359.1 1.5 1.6e-57 193.8 0.2 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain OrfB_Zn_ribbon PF07282.11 OAG12708.1 - 0.046 13.7 0.1 8.2 6.4 0.0 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.12 OAG12708.1 - 0.56 10.2 3.0 2.3 8.2 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_2 PF13240.6 OAG12708.1 - 7.9 6.3 9.6 8.3 6.3 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Rpr2 PF04032.16 OAG12709.1 - 7.7e-11 42.1 0.9 1.4e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 OAG12709.1 - 0.061 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Nudix N-terminal DUF4674 PF15719.5 OAG12709.1 - 0.077 13.0 7.0 1.6 8.7 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) GFA PF04828.14 OAG12709.1 - 0.54 10.6 3.1 1.3 9.4 0.0 2.3 2 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DBR1 PF05011.13 OAG12710.1 - 3.7e-45 153.8 0.0 7.8e-45 152.7 0.0 1.5 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OAG12710.1 - 7.8e-06 26.5 1.0 1.6e-05 25.6 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TMA7 PF09072.10 OAG12711.1 - 7.2e-17 62.0 16.0 8e-17 61.8 16.0 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 Sugar_tr PF00083.24 OAG12712.1 - 2.3e-100 336.6 23.2 2.6e-100 336.4 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG12712.1 - 1.7e-37 129.2 44.3 3.9e-31 108.3 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG12712.1 - 7.6e-05 21.2 1.1 7.6e-05 21.2 1.1 2.7 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 OAG12712.1 - 0.1 11.2 26.0 0.018 13.6 5.7 3.4 2 2 1 3 3 3 0 MFS/sugar transport protein APS_kinase PF01583.20 OAG12714.1 - 9.7e-71 236.8 0.0 1.2e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAG12714.1 - 4.8e-05 23.5 0.0 9.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG12714.1 - 0.00016 22.3 0.0 0.00024 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAG12714.1 - 0.0019 17.7 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 OAG12714.1 - 0.032 14.6 0.1 0.046 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OAG12714.1 - 0.033 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 OAG12714.1 - 0.037 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit 6PF2K PF01591.18 OAG12714.1 - 0.085 12.1 0.0 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF463 PF04317.12 OAG12714.1 - 0.15 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 ABC_tran PF00005.27 OAG12714.1 - 0.15 12.6 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter DENN PF02141.21 OAG12715.1 - 1.9e-41 142.0 0.1 3.3e-41 141.3 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OAG12715.1 - 4.3e-06 27.4 0.1 1.4e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 OAG12715.1 - 0.0061 17.1 4.8 0.0061 17.1 4.8 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A MCC-bdg_PDZ PF10506.9 OAG12715.1 - 0.092 12.8 1.5 0.31 11.1 1.5 2.0 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF724 PF05266.14 OAG12715.1 - 0.87 9.4 8.9 2.1 8.1 8.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 OAG12715.1 - 9.7 5.4 15.1 0.99 8.6 4.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zf-HIT PF04438.16 OAG12716.1 - 9.3e-10 38.2 10.5 1.3e-09 37.7 10.5 1.2 1 0 0 1 1 1 1 HIT zinc finger p450 PF00067.22 OAG12717.1 - 4.5e-06 25.7 1.5 0.00019 20.3 0.5 1.9 1 1 1 2 2 2 2 Cytochrome P450 Ank_2 PF12796.7 OAG12718.1 - 8e-20 71.2 1.7 5.2e-09 36.6 0.8 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG12718.1 - 3.9e-14 51.4 1.8 0.011 16.2 0.4 6.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OAG12718.1 - 4.5e-14 52.6 1.3 2.7e-05 24.6 0.4 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG12718.1 - 3.9e-09 36.5 7.4 0.029 14.8 1.0 6.0 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAG12718.1 - 1.4e-08 34.9 1.2 0.089 13.1 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) AAA_22 PF13401.6 OAG12718.1 - 1.7e-06 28.4 0.0 7.1e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG12718.1 - 0.00033 20.6 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 OAG12718.1 - 0.0048 17.3 0.0 0.027 14.9 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HTH_15 PF12324.8 OAG12718.1 - 0.038 14.0 0.0 0.23 11.4 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase Glyco_transf_25 PF01755.17 OAG12719.1 - 2.4e-10 40.6 0.0 1e-09 38.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Fe_hyd_lg_C PF02906.14 OAG12720.1 - 1.9e-50 171.8 0.0 3.7e-50 170.9 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Pkinase PF00069.25 OAG12722.1 - 8.6e-54 182.7 0.0 1.3e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12722.1 - 2.1e-30 105.9 0.0 3.4e-29 101.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG12722.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OAG12722.1 - 0.062 12.3 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase adh_short PF00106.25 OAG12726.1 - 6.7e-15 55.1 0.0 8.5e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12726.1 - 3.5e-14 52.9 0.2 5.1e-14 52.4 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.13 OAG12726.1 - 0.0043 17.0 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family zinc_ribbon_4 PF13717.6 OAG12728.1 - 0.046 13.6 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DFRP_C PF16543.5 OAG12729.1 - 1.2e-25 89.8 8.7 1.2e-25 89.8 8.7 3.4 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 OAG12729.1 - 7.8e-06 25.7 3.4 7.8e-06 25.7 3.4 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAG12729.1 - 0.00014 21.6 12.1 0.0028 17.4 4.8 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 OAG12729.1 - 0.00017 22.2 18.4 0.00037 21.2 6.1 3.9 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 OAG12729.1 - 0.0045 17.2 0.9 0.34 11.1 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 OAG12729.1 - 0.019 15.0 10.2 0.019 15.0 10.2 3.2 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_2 PF14608.6 OAG12729.1 - 0.43 11.1 15.8 0.99 10.0 6.5 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ost4 PF10215.9 OAG12730.1 - 7.7e-21 73.6 1.4 8.7e-21 73.5 1.4 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase zf-C2H2_aberr PF17017.5 OAG12731.1 - 0.0051 17.0 1.0 0.0082 16.3 1.0 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger FOXP-CC PF16159.5 OAG12731.1 - 0.027 15.1 0.7 0.027 15.1 0.7 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain RR_TM4-6 PF06459.12 OAG12731.1 - 1.1 9.0 11.9 3.1 7.5 11.9 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 OAG12731.1 - 1.7 7.5 12.6 2.6 6.8 12.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-C2H2_4 PF13894.6 OAG12731.1 - 3.3 8.8 4.7 8.1 7.6 1.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Selenoprotein_S PF06936.11 OAG12731.1 - 3.6 7.4 15.1 12 5.7 15.1 1.8 1 0 0 1 1 1 0 Selenoprotein S (SelS) SLC12 PF03522.15 OAG12731.1 - 6.3 5.7 5.6 13 4.7 5.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 DUF1682 PF07946.14 OAG12731.1 - 7.8 5.6 15.1 14 4.8 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ribosomal_L26 PF16906.5 OAG12732.1 - 4.3e-37 126.4 2.6 5.7e-37 126.0 2.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OAG12732.1 - 7e-07 29.0 0.6 1.6e-06 27.8 0.6 1.6 1 0 0 1 1 1 1 KOW motif Methyltransf_23 PF13489.6 OAG12733.1 - 4.1e-10 39.7 0.0 5.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG12733.1 - 2.5e-09 37.6 0.0 4.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG12733.1 - 6.8e-07 29.9 0.0 1.5e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG12733.1 - 9.7e-05 23.0 0.0 0.00027 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG12733.1 - 0.00029 20.6 0.0 0.0006 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG12733.1 - 0.00072 19.0 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF2194 PF09960.9 OAG12733.1 - 0.037 12.4 0.0 0.046 12.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Methyltransf_8 PF05148.15 OAG12733.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase adh_short PF00106.25 OAG12734.1 - 1e-25 90.3 0.1 1.3e-25 90.1 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12734.1 - 1.7e-22 80.1 0.1 2.2e-22 79.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12734.1 - 1.5e-05 25.0 0.0 2.2e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 KR domain Glyco_transf_8 PF01501.20 OAG12736.1 - 8.1e-07 28.9 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Acyl_transf_3 PF01757.22 OAG12737.1 - 7.2e-31 107.5 31.4 8.6e-31 107.2 31.4 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.15 OAG12738.1 - 3.5e-13 50.0 0.1 9.2e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OAG12738.1 - 3e-05 23.5 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Pyr_redox_2 PF07992.14 OAG12739.1 - 1.6e-17 63.7 0.0 3.4e-17 62.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG12739.1 - 1.1e-06 28.2 0.1 0.03 13.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG12739.1 - 5.5e-05 22.4 0.5 0.18 10.9 0.2 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 OAG12739.1 - 0.00025 19.9 0.1 0.014 14.1 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG12739.1 - 0.0015 17.7 0.3 0.0029 16.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thyroglob_assoc PF16597.5 OAG12739.1 - 0.0045 17.3 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain NAD_binding_8 PF13450.6 OAG12739.1 - 0.02 15.1 0.1 0.051 13.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG12739.1 - 0.053 13.5 0.4 9.3 6.2 0.0 2.5 1 1 1 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG12739.1 - 0.08 12.1 0.0 5.6 6.0 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAG12739.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Leo1 PF04004.13 OAG12740.1 - 5.6e-38 130.4 0.1 1.1e-37 129.5 0.1 1.5 1 0 0 1 1 1 1 Leo1-like protein DUF4800 PF16057.5 OAG12740.1 - 0.02 14.2 0.6 0.031 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Mob1_phocein PF03637.17 OAG12741.1 - 1.7e-42 145.3 0.0 9.1e-42 142.9 0.0 1.9 1 1 0 1 1 1 1 Mob1/phocein family Fe_dep_repr_C PF02742.15 OAG12741.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Arf PF00025.21 OAG12742.1 - 4.5e-80 267.2 0.2 5.2e-80 267.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG12742.1 - 1.6e-14 54.2 0.0 2.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG12742.1 - 2.4e-14 53.2 0.0 3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG12742.1 - 1.5e-13 50.7 1.4 1.2e-09 37.8 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAG12742.1 - 5.1e-13 48.9 0.0 5.5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG12742.1 - 9.2e-11 41.5 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG12742.1 - 3.6e-06 27.0 0.0 5.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAG12742.1 - 0.01 15.2 0.7 0.024 14.0 0.7 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase TPM_phosphatase PF04536.14 OAG12742.1 - 0.12 12.5 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 TPM domain PDE8 PF08629.10 OAG12743.1 - 0.006 16.6 0.8 42 4.2 0.0 4.5 2 2 3 5 5 5 2 PDE8 phosphodiesterase Keratin PF02422.16 OAG12743.1 - 0.76 9.5 3.1 33 4.3 0.0 3.1 2 1 0 3 3 3 0 Keratin PPR_2 PF13041.6 OAG12744.1 - 1.4e-05 25.2 0.1 0.019 15.1 0.0 3.7 4 1 1 5 5 5 3 PPR repeat family PPR_long PF17177.4 OAG12744.1 - 0.00029 20.3 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 OAG12744.1 - 0.022 14.8 0.0 2.7 8.1 0.0 3.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR PF01535.20 OAG12744.1 - 0.051 13.8 0.0 26 5.3 0.1 3.6 4 0 0 4 4 4 0 PPR repeat AhpC-TSA_2 PF13911.6 OAG12745.1 - 7.2e-08 32.5 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 OAG12745.1 - 1.3e-07 31.6 0.0 2.2e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Methyltransf_11 PF08241.12 OAG12746.1 - 0.061 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAG12746.1 - 0.065 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Xan_ur_permease PF00860.20 OAG12747.1 - 4.5e-26 91.5 26.8 1.6e-25 89.7 24.8 2.5 2 1 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 OAG12747.1 - 0.02 15.3 4.3 0.02 15.3 4.3 3.2 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF3488 PF11992.8 OAG12747.1 - 0.56 9.1 4.0 1.5 7.7 4.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) TRAM_LAG1_CLN8 PF03798.16 OAG12749.1 - 1.7e-47 161.7 10.2 1.7e-47 161.7 10.2 1.4 2 0 0 2 2 2 1 TLC domain RRM_1 PF00076.22 OAG12750.1 - 7.5e-10 38.5 2.5 0.00049 19.9 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calx-beta PF03160.14 OAG12750.1 - 0.12 12.6 2.0 0.25 11.5 0.4 2.2 2 0 0 2 2 2 0 Calx-beta domain GATase_7 PF13537.6 OAG12750.1 - 0.13 12.2 0.1 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Glutamine amidotransferase domain DUF3235 PF11574.8 OAG12750.1 - 0.22 12.4 1.6 0.29 12.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) p450 PF00067.22 OAG12751.1 - 9.6e-60 202.6 0.0 1.2e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.18 OAG12752.1 - 3.5e-52 177.2 0.0 4.7e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG12752.1 - 3.3e-32 110.9 0.1 5.5e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal E1_FCCH PF16190.5 OAG12752.1 - 0.017 15.3 0.7 0.061 13.5 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain HgmA PF04209.13 OAG12753.1 - 3e-203 675.2 0.1 3.5e-203 675.0 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase RtcB PF01139.17 OAG12754.1 - 4.1e-51 174.5 0.0 4.6e-37 128.2 0.0 3.5 1 1 1 2 2 2 2 tRNA-splicing ligase RtcB Sod_Cu PF00080.20 OAG12756.1 - 1.5e-13 51.1 0.5 6.3e-13 49.1 0.0 1.9 1 1 1 2 2 2 1 Copper/zinc superoxide dismutase (SODC) DUF2262 PF10020.9 OAG12756.1 - 0.0066 16.9 0.0 0.009 16.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2262) Acetyltransf_1 PF00583.25 OAG12757.1 - 1.6e-07 31.5 0.2 2.1e-07 31.2 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG12757.1 - 1.8e-07 31.1 0.0 9.2e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG12757.1 - 2.7e-07 30.9 0.0 4.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG12757.1 - 0.0001 22.2 0.1 0.00019 21.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 OAG12757.1 - 0.0027 17.4 0.2 0.0079 15.9 0.0 1.8 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG12757.1 - 0.0033 17.5 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 OAG12757.1 - 0.0047 17.6 0.0 0.0061 17.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RTP1_C1 PF10363.9 OAG12758.1 - 1.1e-20 73.9 0.2 3.8e-19 68.9 0.0 2.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 OAG12758.1 - 1e-05 25.1 0.2 2.2e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 LSM PF01423.22 OAG12759.1 - 2.5e-19 68.7 0.2 2.9e-19 68.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.13 OAG12760.1 - 2.5e-67 225.6 1.0 2.8e-67 225.5 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) T4_baseplate PF12322.8 OAG12760.1 - 0.01 15.3 1.5 0.19 11.2 0.1 2.1 1 1 1 2 2 2 0 T4 bacteriophage base plate protein DUF4379 PF14311.6 OAG12760.1 - 0.029 14.7 1.3 0.029 14.7 1.3 1.9 1 1 1 2 2 2 0 Probable Zinc-ribbon domain Terminase_GpA PF05876.12 OAG12760.1 - 0.086 11.4 1.0 0.11 11.1 1.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Zn_Tnp_IS1595 PF12760.7 OAG12760.1 - 0.11 12.5 3.0 0.31 11.1 3.0 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 OAG12760.1 - 0.12 12.3 2.3 7.2 6.6 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF3716 PF12511.8 OAG12760.1 - 0.12 12.4 2.5 0.21 11.7 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Cytochrom_c3_2 PF14537.6 OAG12760.1 - 0.18 12.3 3.7 0.35 11.4 3.7 1.4 1 1 0 1 1 1 0 Cytochrome c3 Fungal_trans_2 PF11951.8 OAG12761.1 - 1.3e-22 80.1 2.2 1.9e-22 79.7 2.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG12761.1 - 2.1e-08 34.2 12.7 3.1e-08 33.6 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKI PF01202.22 OAG12761.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase DHDPS PF00701.22 OAG12762.1 - 1.6e-36 125.5 0.0 2e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Sugar_tr PF00083.24 OAG12763.1 - 7.3e-98 328.4 29.7 9.2e-98 328.0 29.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG12763.1 - 1.5e-21 76.7 20.1 1.5e-21 76.7 20.1 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily HHV-5_US34A PF17087.5 OAG12763.1 - 0.28 11.4 1.8 2 8.7 0.3 2.3 2 0 0 2 2 2 0 Herpesvirus US34A protein family CorA PF01544.18 OAG12764.1 - 4.6e-10 39.3 6.1 1.1e-07 31.5 0.9 2.9 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 OAG12764.1 - 0.39 10.8 2.8 0.74 9.9 2.8 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Fungal_trans PF04082.18 OAG12765.1 - 0.0016 17.5 0.7 0.004 16.2 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG12766.1 - 1.4e-35 122.9 38.5 1.4e-35 122.9 38.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG12766.1 - 4e-09 35.5 19.8 5.9e-09 34.9 19.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rot1 PF10681.9 OAG12769.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal FliT PF05400.13 OAG12770.1 - 0.12 13.2 0.4 2.6 8.9 0.2 2.6 2 0 0 2 2 2 0 Flagellar protein FliT Rad60-SLD_2 PF13881.6 OAG12772.1 - 5.5e-13 49.0 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG12772.1 - 0.0001 22.8 0.0 0.00017 22.1 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAG12772.1 - 0.00042 20.0 0.0 0.00073 19.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TRI12 PF06609.13 OAG12773.1 - 7.6e-24 84.1 19.2 9.4e-24 83.8 19.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG12773.1 - 5.7e-18 65.0 40.4 5.7e-18 65.0 40.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 OAG12773.1 - 2.8 8.2 9.3 0.17 12.2 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) DUF92 PF01940.16 OAG12774.1 - 2.1e-83 279.4 4.8 2.8e-83 279.0 4.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 UMP1 PF05348.11 OAG12774.1 - 6e-40 136.1 0.1 1e-39 135.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 5TM-5TMR_LYT PF07694.12 OAG12774.1 - 0.33 10.4 6.8 1.8 8.1 1.3 2.4 2 0 0 2 2 2 0 5TMR of 5TMR-LYT MFS_1 PF07690.16 OAG12775.1 - 2.9e-23 82.4 37.4 2.9e-23 82.4 37.4 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG12775.1 - 2.8e-07 29.4 15.4 3.6e-07 29.0 15.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PikAIV_N PF18605.1 OAG12775.1 - 0.24 11.0 2.3 0.41 10.3 2.3 1.3 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain zf-H2C2_2 PF13465.6 OAG12777.1 - 2.7e-11 43.3 43.4 2.1e-05 24.7 0.7 7.1 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 OAG12777.1 - 1.5e-06 28.3 55.4 0.015 15.7 1.2 7.7 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG12777.1 - 0.0013 19.4 47.2 0.45 11.5 0.4 8.2 8 0 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OAG12777.1 - 0.0032 17.2 6.2 0.0032 17.2 6.2 5.9 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 OAG12777.1 - 0.0093 16.2 14.0 0.081 13.2 1.2 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 OAG12777.1 - 0.055 13.1 0.5 0.055 13.1 0.5 3.4 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 OAG12777.1 - 0.25 11.8 16.7 8.3 7.0 0.4 5.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type SH3_9 PF14604.6 OAG12779.1 - 2.3e-05 24.2 0.2 4e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG12779.1 - 0.00049 19.6 0.1 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF4690 PF15756.5 OAG12779.1 - 0.0022 18.5 1.2 0.0082 16.7 1.2 2.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 OAG12779.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Podoplanin Mid2 PF04478.12 OAG12779.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DehI PF10778.9 OAG12781.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI Ig_mannosidase PF17753.1 OAG12782.1 - 1.3e-20 72.9 0.1 3.5e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 OAG12782.1 - 5.5e-13 49.3 0.1 2.2e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAG12782.1 - 1.3e-06 29.0 0.0 3.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 HET PF06985.11 OAG12783.1 - 5.4e-26 91.7 0.0 1.7e-25 90.1 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG12788.1 - 4e-35 121.4 55.9 4e-35 121.4 55.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG12788.1 - 5.6e-16 58.1 27.6 8.3e-16 57.5 27.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG12788.1 - 7.2e-11 41.6 6.9 7.2e-11 41.6 6.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Pox_A14 PF05767.12 OAG12788.1 - 0.93 9.7 0.0 0.93 9.7 0.0 3.0 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 CPL PF08144.11 OAG12790.1 - 7.6e-20 71.7 4.2 6.1e-19 68.8 0.0 3.6 3 0 0 3 3 3 1 CPL (NUC119) domain Ank_2 PF12796.7 OAG12791.1 - 1.1e-11 45.1 2.8 8e-06 26.4 0.2 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG12791.1 - 2.7e-09 37.1 0.1 1.1e-05 25.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG12791.1 - 2.9e-06 27.7 0.0 8.4e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG12791.1 - 7.6e-06 25.9 0.0 0.00024 21.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OAG12791.1 - 0.014 15.8 0.0 0.19 12.2 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeat DnaG_DnaB_bind PF08278.11 OAG12791.1 - 0.03 14.9 6.3 7 7.3 6.3 2.6 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding FliT PF05400.13 OAG12791.1 - 1.1 10.1 4.8 5.6 7.9 0.4 2.5 2 1 0 2 2 2 0 Flagellar protein FliT PAP2 PF01569.21 OAG12792.1 - 2.5e-26 92.0 4.2 9e-26 90.3 4.2 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OAG12792.1 - 0.00019 21.2 4.3 0.033 13.9 0.1 3.0 1 1 2 3 3 3 2 PAP2 superfamily zf-U1 PF06220.12 OAG12793.1 - 7.1e-09 35.3 0.6 1.1e-08 34.7 0.6 1.3 1 0 0 1 1 1 1 U1 zinc finger TetR_C_6 PF13977.6 OAG12793.1 - 0.076 13.2 0.5 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Hira PF07569.11 OAG12794.1 - 4.2e-81 271.9 0.0 1.3e-80 270.3 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 OAG12794.1 - 5.7e-27 93.4 19.9 0.00022 22.0 0.1 8.7 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG12794.1 - 3.3e-12 46.5 0.0 0.55 10.6 0.0 6.2 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 OAG12794.1 - 3.9e-11 42.5 2.9 6.8e-11 41.8 1.6 2.1 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 OAG12794.1 - 0.00045 20.1 0.1 1.7 8.6 0.0 4.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OAG12794.1 - 0.024 13.6 1.4 1.5 7.7 0.0 3.7 4 2 2 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 OAG12794.1 - 0.034 13.4 0.2 0.11 11.7 0.1 1.9 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller eIF2A PF08662.11 OAG12794.1 - 0.18 11.6 0.5 13 5.6 0.0 3.5 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A UPF0113 PF03657.13 OAG12795.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 UPF0113 PUA domain Peptidase_M20 PF01546.28 OAG12796.1 - 2.1e-15 57.0 0.1 8.6e-15 55.0 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG12796.1 - 1.6e-14 53.7 0.1 2.7e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 OAG12798.1 - 9.9e-40 136.5 35.3 9.9e-40 136.5 35.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG12798.1 - 5.8e-11 41.9 9.2 5.8e-11 41.9 9.2 3.3 2 2 0 2 2 2 1 Sugar (and other) transporter IMUP PF15761.5 OAG12798.1 - 0.18 12.5 3.0 0.32 11.7 3.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SepZ PF06066.11 OAG12798.1 - 1.2 9.4 3.1 0.8 10.0 0.4 2.0 2 0 0 2 2 2 0 SepZ HbrB PF08539.11 OAG12799.1 - 0.082 12.9 1.6 0.12 12.3 1.5 1.3 1 1 0 1 1 1 0 HbrB-like Transferase PF02458.15 OAG12800.1 - 2.2e-25 89.2 0.0 1.1e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 Transferase family BPL_N PF09825.9 OAG12800.1 - 0.081 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal EthD PF07110.11 OAG12802.1 - 7.4e-15 55.9 0.0 1.1e-14 55.3 0.0 1.3 1 0 0 1 1 1 1 EthD domain CDP-OH_P_transf PF01066.21 OAG12803.1 - 0.28 12.0 1.7 0.54 11.1 1.7 1.7 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase zf-C2H2_6 PF13912.6 OAG12804.1 - 5e-07 29.6 0.6 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG12804.1 - 8.3e-07 29.2 8.4 1.4e-06 28.4 0.8 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAG12804.1 - 3.7e-06 27.1 0.5 3.7e-06 27.1 0.5 3.3 2 1 0 2 2 2 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAG12804.1 - 6.7e-06 26.6 6.6 0.026 15.2 1.7 3.2 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 OAG12804.1 - 4e-05 24.1 3.6 0.0016 19.1 0.4 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger Mating_C PF12737.7 OAG12804.1 - 0.097 11.9 9.6 0.086 12.1 2.0 2.2 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 zf-C2H2_11 PF16622.5 OAG12804.1 - 0.15 11.9 0.3 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 OAG12804.1 - 0.18 12.1 0.7 2.1 8.7 0.2 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OAG12804.1 - 0.39 10.5 2.9 0.72 9.7 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Aldo_ket_red PF00248.21 OAG12805.1 - 1.3e-64 218.2 0.0 1.5e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ceramidase PF05875.12 OAG12806.1 - 5.2e-81 271.9 0.8 6.3e-81 271.7 0.8 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 OAG12806.1 - 0.0076 16.1 1.5 0.033 14.1 1.5 2.1 1 0 0 1 1 1 1 Trp-operon Leader Peptide HATPase_c PF02518.26 OAG12807.1 - 3.9e-22 78.9 0.0 7.1e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG12807.1 - 1.2e-21 77.0 0.1 2.7e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG12807.1 - 5.1e-07 29.6 3.2 2.7e-06 27.3 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 OAG12807.1 - 1.1e-06 29.0 0.0 0.00026 21.3 0.0 2.8 2 0 0 2 2 2 1 GAF domain PAS_4 PF08448.10 OAG12807.1 - 0.005 17.1 0.1 7.9 6.8 0.0 4.8 4 1 1 5 5 5 1 PAS fold Ring_hydroxyl_A PF00848.19 OAG12808.1 - 1.1e-19 71.3 11.2 2e-17 63.9 11.2 2.3 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG12808.1 - 1e-16 60.7 0.0 2.4e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain GCV_T PF01571.21 OAG12809.1 - 4.2e-69 232.8 0.0 3.3e-68 229.8 0.0 2.0 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 OAG12809.1 - 3e-37 129.0 0.8 5.3e-37 128.2 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 OAG12809.1 - 1.6e-19 69.6 0.0 4.2e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 OAG12809.1 - 5.1e-18 65.1 0.1 2.7e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 OAG12809.1 - 6.6e-07 28.8 0.2 0.0022 17.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG12809.1 - 6.9e-07 29.7 0.2 0.0011 19.4 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG12809.1 - 0.00081 18.4 0.3 0.0091 14.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase ThiF PF00899.21 OAG12809.1 - 0.00098 18.5 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.24 OAG12809.1 - 0.0049 16.0 0.2 0.011 14.9 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 OAG12809.1 - 0.0067 16.7 0.8 0.02 15.2 0.2 2.1 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.6 OAG12809.1 - 0.0095 15.2 0.3 0.3 10.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG12809.1 - 0.011 15.7 0.4 4.9 7.1 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG12809.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 OAG12809.1 - 0.042 13.9 0.1 0.078 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG12809.1 - 0.077 12.2 0.8 1.5 8.0 0.4 2.1 2 0 0 2 2 2 0 FAD binding domain DD_K PF12121.8 OAG12809.1 - 0.2 11.8 0.8 0.55 10.4 0.8 1.8 1 0 0 1 1 1 0 Dermaseptin Glyco_hydro_61 PF03443.14 OAG12810.1 - 2.5e-49 168.0 0.1 3e-49 167.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3328 PF11807.8 OAG12812.1 - 6.2e-29 101.3 0.1 6.8e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HET PF06985.11 OAG12813.1 - 1.6e-31 109.6 0.9 2.5e-31 109.0 0.9 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CCER1 PF15482.6 OAG12814.1 - 0.024 14.5 7.2 0.044 13.7 7.2 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 zf-C2H2 PF00096.26 OAG12815.1 - 2e-06 27.9 11.4 2.2e-05 24.6 1.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG12815.1 - 2.8e-05 24.3 2.4 2.8e-05 24.3 2.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG12815.1 - 0.00051 20.6 7.2 0.0078 17.0 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG12815.1 - 0.0009 19.2 0.4 0.0009 19.2 0.4 2.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG12815.1 - 0.012 15.9 0.7 0.028 14.7 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FAM131 PF15010.6 OAG12815.1 - 0.12 12.3 0.9 0.56 10.1 0.1 1.9 1 1 0 2 2 2 0 Putative cell signalling zf-met PF12874.7 OAG12815.1 - 0.24 11.8 0.4 0.24 11.8 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 OAG12815.1 - 3 7.7 6.4 1.8 8.4 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain ATP_bind_1 PF03029.17 OAG12816.1 - 2.5e-62 210.8 0.0 7e-61 206.1 0.0 2.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAG12816.1 - 1.2e-05 25.4 0.0 0.00042 20.4 0.0 2.6 2 1 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG12816.1 - 4.3e-05 23.1 0.0 0.017 14.7 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OAG12816.1 - 0.00078 18.9 0.0 0.12 11.8 0.0 3.0 3 0 0 3 3 3 1 ADP-ribosylation factor family Roc PF08477.13 OAG12816.1 - 0.0011 19.2 0.0 0.22 11.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OAG12816.1 - 0.0012 19.2 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAG12816.1 - 0.0016 18.4 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 OAG12816.1 - 0.0043 16.6 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 OAG12816.1 - 0.0057 16.1 0.0 0.33 10.4 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAG12816.1 - 0.0066 16.4 0.1 13 5.7 0.0 3.4 3 0 0 3 3 3 0 RsgA GTPase cobW PF02492.19 OAG12816.1 - 0.0074 15.9 0.1 0.59 9.7 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OAG12816.1 - 0.0078 16.4 1.8 0.0092 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OAG12816.1 - 0.01 14.8 0.0 0.72 8.8 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 OAG12816.1 - 0.012 14.8 0.0 0.28 10.3 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 OAG12816.1 - 0.019 14.1 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 OAG12816.1 - 0.02 15.0 0.1 0.053 13.6 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain Ras PF00071.22 OAG12816.1 - 0.023 14.3 0.0 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_30 PF13604.6 OAG12816.1 - 0.026 14.3 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG12816.1 - 0.028 14.8 0.0 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 OAG12816.1 - 0.029 14.7 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 OAG12816.1 - 0.034 13.6 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 OAG12816.1 - 0.037 13.3 0.5 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 OAG12816.1 - 0.042 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 OAG12816.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG12816.1 - 0.053 14.1 0.2 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 OAG12816.1 - 0.055 12.7 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Septin PRK PF00485.18 OAG12816.1 - 0.065 13.0 0.3 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 OAG12816.1 - 0.076 12.4 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.22 OAG12816.1 - 0.083 12.5 0.4 0.38 10.4 0.0 2.2 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 OAG12816.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 OAG12816.1 - 0.45 10.5 3.4 1.2 9.2 0.2 2.8 2 1 0 2 2 2 0 Dynamin family CwfJ_C_1 PF04677.15 OAG12817.1 - 3.8e-27 94.6 0.0 6e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OAG12817.1 - 4.7e-25 88.4 0.3 4.7e-25 88.4 0.3 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 HGTP_anticodon PF03129.20 OAG12817.1 - 0.059 13.5 0.0 0.25 11.5 0.0 2.2 1 0 0 1 1 1 0 Anticodon binding domain FMO-like PF00743.19 OAG12818.1 - 3.8e-11 42.1 0.2 1.5e-09 36.9 0.3 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG12818.1 - 2.8e-09 36.7 0.0 3.9e-07 29.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG12818.1 - 3.9e-05 23.0 0.0 0.0013 18.0 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG12818.1 - 7.7e-05 22.0 0.1 0.021 14.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG12818.1 - 0.0012 19.0 0.2 0.0081 16.4 0.2 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CK_II_beta PF01214.18 OAG12819.1 - 9e-77 257.0 0.0 2.2e-76 255.7 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DUF4637 PF15470.6 OAG12819.1 - 0.086 12.6 3.2 0.2 11.3 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RRN3 PF05327.11 OAG12819.1 - 0.3 9.6 1.2 0.43 9.1 1.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 OAG12819.1 - 2.1 8.1 7.7 5.1 6.8 3.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Spt5_N PF11942.8 OAG12819.1 - 2.3 9.2 15.1 0.087 13.8 7.5 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DNA_pol_phi PF04931.13 OAG12819.1 - 3.8 5.5 5.3 5.2 5.1 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAG12819.1 - 4.6 6.5 6.4 7.8 5.7 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein SPT6_acidic PF14632.6 OAG12819.1 - 5.5 7.6 16.4 9.4 6.9 0.4 3.0 3 0 0 3 3 3 0 Acidic N-terminal SPT6 PTPRCAP PF15713.5 OAG12819.1 - 6.4 7.0 8.2 11 6.3 5.6 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 OAG12819.1 - 8.1 4.6 5.6 13 4.0 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans PF04082.18 OAG12820.1 - 4e-15 55.6 0.0 8.6e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG12820.1 - 2.1e-08 34.1 8.7 3.9e-08 33.3 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL5 PF02025.15 OAG12820.1 - 0.064 13.5 0.0 0.89 9.9 0.0 2.3 2 0 0 2 2 2 0 Interleukin 5 FMO-like PF00743.19 OAG12821.1 - 1.2e-12 47.0 0.0 2.3e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG12821.1 - 3.3e-11 43.2 0.0 1.3e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG12821.1 - 1.9e-10 40.5 0.2 7.6e-05 22.1 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG12821.1 - 1.4e-06 27.7 0.1 0.0016 17.7 0.0 2.8 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG12821.1 - 3.7e-05 23.1 0.0 0.00064 19.0 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG12821.1 - 0.0017 18.0 0.6 0.027 14.0 0.3 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG12821.1 - 0.018 15.0 0.0 0.11 12.5 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG12821.1 - 0.019 14.2 0.1 0.14 11.4 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG12821.1 - 0.17 12.4 0.5 0.6 10.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tfb4 PF03850.14 OAG12822.1 - 1.7e-103 345.9 0.0 2e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.13 OAG12822.1 - 0.2 11.7 5.1 0.36 10.9 5.1 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Asparaginase_2 PF01112.18 OAG12823.1 - 3.4e-50 170.8 3.8 6.9e-33 114.0 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.19 OAG12824.1 - 8.8e-89 297.9 0.0 2.7e-86 289.7 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAG12824.1 - 0.00052 18.9 0.0 0.033 13.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein tRNA_U5-meth_tr PF05958.11 OAG12825.1 - 1.5e-13 50.5 0.0 2.1e-12 46.8 0.0 2.6 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 OAG12825.1 - 5.8e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 OAG12825.1 - 0.0025 17.2 0.1 0.0044 16.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAG12825.1 - 0.0035 18.0 0.0 0.0083 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OAG12825.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 OAG12825.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 OAG12825.1 - 0.11 11.7 0.0 0.86 8.7 0.0 2.0 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Ribosomal_S5_C PF03719.15 OAG12826.1 - 8.2e-22 76.4 0.0 1.6e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 OAG12826.1 - 8.2e-17 61.0 0.2 2.2e-16 59.6 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Metal_resist PF13801.6 OAG12826.1 - 1 9.6 9.1 0.53 10.5 2.4 2.5 2 0 0 2 2 2 0 Heavy-metal resistance DASH_Dad3 PF08656.10 OAG12827.1 - 4.1e-29 100.5 0.3 4.9e-29 100.2 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.25 OAG12828.1 - 1.8e-73 247.2 0.0 2.8e-73 246.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12828.1 - 1.5e-30 106.3 0.0 3.3e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG12828.1 - 4.8e-06 26.1 0.0 0.52 9.6 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 OAG12828.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG12828.1 - 0.016 14.0 0.7 0.025 13.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAG12828.1 - 0.033 14.1 0.0 0.46 10.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Adaptin_binding PF10199.9 OAG12830.1 - 0.041 14.5 0.4 0.11 13.1 0.4 1.7 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Mre11_DNA_bind PF04152.14 OAG12831.1 - 7.7e-51 172.8 3.4 7.7e-51 172.8 3.4 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OAG12831.1 - 2.4e-14 54.3 2.8 4.9e-14 53.3 2.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG12831.1 - 3.1e-06 27.5 0.4 3.7e-05 24.0 0.4 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AP3D1 PF06375.11 OAG12831.1 - 0.032 14.5 0.6 0.032 14.5 0.6 3.3 2 1 1 3 3 3 0 AP-3 complex subunit delta-1 DUF778 PF05608.12 OAG12831.1 - 0.11 12.9 1.3 0.18 12.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Ribosomal_S19 PF00203.21 OAG12832.1 - 1.5e-26 92.0 0.1 1.8e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 OAG12833.1 - 2.8e-22 78.4 0.2 4.6e-22 77.7 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Acyl-CoA_dh_1 PF00441.24 OAG12834.1 - 2.8e-32 112.0 2.4 3.8e-32 111.6 2.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG12834.1 - 3e-21 75.4 0.1 5.1e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG12834.1 - 6.5e-16 59.0 0.3 3.4e-15 56.7 0.0 2.4 2 2 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG12834.1 - 2.6e-08 34.2 0.4 3.7e-08 33.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 OAG12835.1 - 1.9e-33 115.6 0.2 3.4e-33 114.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG12835.1 - 0.00025 21.1 15.5 0.00042 20.4 15.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_kinase PF01633.20 OAG12836.1 - 8.3e-48 162.8 0.0 1.6e-45 155.4 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 OAG12836.1 - 8.1e-07 29.2 0.1 7.3e-06 26.1 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Sterol-sensing PF12349.8 OAG12837.1 - 8.2e-30 103.7 1.6 1.7e-29 102.6 1.6 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAG12837.1 - 1.1e-05 23.7 3.7 1.7e-05 23.2 3.7 1.1 1 0 0 1 1 1 1 Patched family TPR_2 PF07719.17 OAG12838.1 - 3.2e-09 36.2 0.0 0.0035 17.3 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG12838.1 - 3.9e-09 36.7 5.2 7.9e-06 26.1 0.1 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG12838.1 - 2.2e-07 31.1 12.1 0.14 13.0 0.0 4.9 3 2 3 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG12838.1 - 3.2e-07 30.0 0.7 0.0018 18.4 0.0 4.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG12838.1 - 8.2e-06 25.4 0.2 0.13 12.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG12838.1 - 5.2e-05 23.8 9.5 0.59 10.8 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG12838.1 - 0.00014 22.3 11.4 3.8 8.1 0.0 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG12838.1 - 0.00024 20.6 2.7 0.027 13.8 0.0 2.4 2 1 0 2 2 2 2 MalT-like TPR region ANAPC3 PF12895.7 OAG12838.1 - 0.0083 16.3 0.0 10 6.4 0.0 3.1 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 OAG12838.1 - 0.013 15.3 3.4 0.13 11.9 0.0 3.1 2 2 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 OAG12838.1 - 0.027 15.1 4.6 17 6.3 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG12838.1 - 0.23 11.6 5.0 3.7 7.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG12838.1 - 0.26 11.2 6.8 27 4.8 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG12838.1 - 0.27 11.4 9.8 0.54 10.4 0.3 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 OAG12838.1 - 8.5 6.8 11.6 18 5.8 11.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RWD PF05773.22 OAG12839.1 - 7.4e-24 84.3 0.7 7.4e-24 84.3 0.7 1.6 2 0 0 2 2 2 1 RWD domain KinB_sensor PF16767.5 OAG12839.1 - 0.064 13.7 2.3 0.11 13.0 2.3 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB DFRP_C PF16543.5 OAG12839.1 - 0.22 12.0 17.9 1.1 9.8 17.6 2.2 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 O-antigen_lig PF13425.6 OAG12839.1 - 0.64 8.7 2.0 0.79 8.4 2.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Complex1_LYR PF05347.15 OAG12840.1 - 1.8e-08 34.3 0.8 1.8e-08 34.3 0.8 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG12840.1 - 0.017 15.9 5.2 0.13 13.0 1.1 2.8 1 1 1 2 2 2 0 Complex1_LYR-like HAD_SAK_2 PF18143.1 OAG12840.1 - 0.073 13.4 0.0 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins UQ_con PF00179.26 OAG12841.1 - 2e-15 56.7 0.0 2.2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG12841.1 - 0.0023 18.2 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.7 OAG12842.1 - 2.6e-38 131.4 5.6 3.6e-38 130.9 0.9 3.6 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 OAG12842.1 - 1.5e-19 70.4 14.3 9.6e-18 64.5 1.6 3.8 2 1 1 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 OAG12842.1 - 8.8e-15 53.9 0.9 3.2e-12 45.5 0.3 3.1 3 0 0 3 3 3 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 OAG12842.1 - 0.00082 19.2 3.2 5.2 7.0 0.0 5.2 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) Ipi1_N PF12333.8 OAG12842.1 - 0.0027 18.3 4.7 0.26 11.9 0.0 5.1 6 0 0 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Zn_clus PF00172.18 OAG12843.1 - 0.013 15.6 7.9 0.032 14.3 7.9 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_8 PF13523.6 OAG12843.1 - 0.021 14.5 0.8 0.049 13.3 0.8 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.8 OAG12844.1 - 1.8e-05 23.8 0.2 0.00024 20.1 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain TPR_1 PF00515.28 OAG12845.1 - 4.4e-08 32.6 0.4 0.011 15.5 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG12845.1 - 6.1e-06 26.0 0.6 0.16 12.1 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG12845.1 - 1.2e-05 25.5 0.6 3.3e-05 24.1 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG12845.1 - 8e-05 22.4 0.0 0.016 15.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG12845.1 - 0.00093 18.8 1.8 0.0038 16.9 0.1 2.7 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 OAG12845.1 - 0.02 15.4 0.5 0.11 13.0 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.6 OAG12846.1 - 1.4e-16 61.1 0.0 2.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG12846.1 - 6.4e-08 33.1 0.0 1.5e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG12846.1 - 0.0029 17.6 0.0 0.0084 16.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 OAG12846.1 - 0.099 13.0 0.0 0.21 12.0 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Snf7 PF03357.21 OAG12847.1 - 2.2e-26 92.5 10.8 2.2e-26 92.5 10.8 1.6 1 1 1 2 2 2 1 Snf7 Cob_adeno_trans PF01923.18 OAG12847.1 - 0.026 14.6 1.4 0.026 14.6 1.4 2.2 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Gon7 PF08738.10 OAG12847.1 - 0.066 13.3 3.1 1.2 9.3 1.0 2.6 2 0 0 2 2 2 0 Gon7 family Tom5 PF10642.9 OAG12847.1 - 0.2 11.7 1.5 12 6.1 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase TPR_MLP1_2 PF07926.12 OAG12847.1 - 0.33 11.0 19.2 0.11 12.6 8.2 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein MerR-DNA-bind PF09278.11 OAG12847.1 - 0.59 10.7 8.7 3.4 8.3 0.4 3.4 3 0 0 3 3 3 0 MerR, DNA binding GAS PF13851.6 OAG12847.1 - 0.82 9.0 16.0 0.028 13.8 8.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding YlqD PF11068.8 OAG12847.1 - 2.8 8.3 14.7 1.2 9.5 9.7 2.2 2 0 0 2 2 2 0 YlqD protein CS PF04969.16 OAG12849.1 - 1.6e-05 25.9 0.1 2.7e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 CS domain HRI1 PF16815.5 OAG12849.1 - 0.07 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein HRI1 MFS_1 PF07690.16 OAG12850.1 - 1.2e-32 113.2 49.8 4.6e-31 108.0 49.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Fst_toxin PF13955.6 OAG12850.1 - 2 8.4 6.0 0.92 9.5 0.5 2.7 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system Acetyltransf_1 PF00583.25 OAG12851.1 - 7.7e-13 48.7 0.0 9.3e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG12851.1 - 4.1e-09 36.4 0.0 5.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG12851.1 - 2.6e-08 34.2 0.1 3.5e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG12851.1 - 2.1e-07 30.8 0.1 2.7e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAG12851.1 - 0.0018 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAG12851.1 - 0.0093 16.0 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG12851.1 - 0.017 15.3 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OAG12851.1 - 0.16 12.0 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase SGL PF08450.12 OAG12852.1 - 6.7e-20 71.7 0.1 1.7e-18 67.1 0.1 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OAG12852.1 - 9.6e-07 28.8 0.0 3.6e-05 23.8 0.0 3.2 4 0 0 4 4 4 1 Strictosidine synthase NHL PF01436.21 OAG12852.1 - 0.043 13.9 0.0 0.26 11.4 0.0 2.4 1 0 0 1 1 1 0 NHL repeat Arylesterase PF01731.20 OAG12852.1 - 0.16 12.2 0.7 4.4 7.6 0.1 3.0 2 1 1 3 3 3 0 Arylesterase Sugar_tr PF00083.24 OAG12853.1 - 2e-10 40.2 3.1 1.2e-07 31.0 0.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Peptidase_M24 PF00557.24 OAG12854.1 - 2.3e-36 125.4 0.7 3.7e-36 124.8 0.7 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_L12 PF00542.19 OAG12854.1 - 0.12 12.7 1.1 27 5.2 0.0 3.4 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain DAP3 PF10236.9 OAG12854.1 - 0.15 11.2 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DEAD PF00270.29 OAG12856.1 - 6.3e-48 162.8 0.0 1.6e-46 158.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG12856.1 - 6e-26 91.0 0.0 3.4e-25 88.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG12856.1 - 8.8e-06 25.8 0.0 3.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG12856.1 - 0.11 11.8 0.0 0.11 11.8 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit BOP1NT PF08145.12 OAG12857.1 - 3.4e-103 345.1 7.8 4.7e-103 344.6 7.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OAG12857.1 - 3.5e-22 78.3 2.1 6.6e-08 33.1 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG12857.1 - 1.9e-07 31.3 0.0 0.0014 18.9 0.0 4.4 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG12857.1 - 0.054 12.1 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Autophagy_N PF03986.13 OAG12857.1 - 0.43 10.5 2.6 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain HLH PF00010.26 OAG12858.1 - 4e-14 52.3 0.3 6.3e-14 51.7 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_Ag35 PF03286.14 OAG12858.1 - 0.012 15.4 2.4 0.012 15.4 2.4 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 OAG12858.1 - 0.016 15.6 5.6 0.028 14.8 5.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 OAG12858.1 - 0.037 13.7 3.0 0.071 12.8 3.0 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 OAG12858.1 - 0.046 13.0 2.4 0.063 12.6 2.4 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAG12858.1 - 0.34 9.1 1.1 0.57 8.4 1.1 1.4 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 OAG12858.1 - 0.59 10.4 6.9 0.049 13.9 1.1 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PBP1_TM PF14812.6 OAG12858.1 - 2.1 8.8 10.1 0.18 12.2 4.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 OAG12858.1 - 3.4 5.7 7.6 4.8 5.2 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 OAG12859.1 - 1.7e-55 188.4 38.5 1.7e-55 188.4 38.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG12859.1 - 1.1e-15 57.5 9.5 1.1e-15 57.5 9.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG12859.1 - 7.8e-08 31.2 1.6 7.8e-08 31.2 1.6 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAG12859.1 - 0.0014 17.1 2.1 0.002 16.6 2.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 OAG12859.1 - 0.031 12.6 15.0 2.1 6.5 8.1 3.8 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GST_C_2 PF13410.6 OAG12860.1 - 6.8e-08 32.4 0.2 1.2e-07 31.7 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG12860.1 - 6.8e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG12860.1 - 0.00011 22.6 0.2 0.00029 21.2 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAG12860.1 - 0.0011 19.5 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG12860.1 - 0.0023 18.1 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG12860.1 - 0.013 15.7 0.3 0.026 14.8 0.3 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain 3Beta_HSD PF01073.19 OAG12861.1 - 4.5e-21 75.1 1.6 7.7e-16 57.9 0.0 3.2 1 1 2 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG12861.1 - 9.8e-08 31.7 1.7 0.0002 20.9 0.0 2.9 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG12861.1 - 0.00015 21.3 0.7 0.53 9.6 0.0 3.5 2 1 2 4 4 4 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG12861.1 - 0.033 13.3 1.7 0.11 11.7 0.0 2.3 2 1 0 3 3 3 0 Polysaccharide biosynthesis protein KR PF08659.10 OAG12861.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 KR domain NAD_binding_4 PF07993.12 OAG12861.1 - 0.19 10.8 0.6 27 3.8 0.0 2.9 2 1 1 3 3 3 0 Male sterility protein Oxidored_FMN PF00724.20 OAG12862.1 - 4.3e-59 200.5 0.0 8.2e-56 189.7 0.0 2.4 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family NPR3 PF03666.13 OAG12863.1 - 1.2e-132 443.1 0.0 1.9e-132 442.4 0.0 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 p450 PF00067.22 OAG12865.1 - 6.2e-78 262.6 0.0 8.1e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OAG12865.1 - 3.3e-32 111.8 0.0 8.2e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG12865.1 - 8.7e-23 81.1 0.0 1.6e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG12865.1 - 8.9e-13 48.8 0.0 3.3e-12 47.0 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CFEM PF05730.11 OAG12866.1 - 0.0082 16.2 9.3 0.021 14.9 9.3 1.8 1 1 0 1 1 1 1 CFEM domain Tim54 PF11711.8 OAG12867.1 - 4.1e-147 489.9 0.5 4.8e-147 489.6 0.5 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pre-PUA PF17832.1 OAG12868.1 - 1.7e-24 86.3 0.4 2.3e-24 85.9 0.4 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OAG12868.1 - 4e-13 49.1 0.0 1.1e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 PUA domain FAD_binding_4 PF01565.23 OAG12869.1 - 2.3e-21 76.0 0.5 4e-21 75.2 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG12869.1 - 1.4e-09 37.9 0.3 2.9e-09 36.9 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Ank_5 PF13857.6 OAG12870.1 - 7.1e-16 58.1 0.1 9.3e-13 48.1 0.0 4.6 3 2 2 5 5 5 1 Ankyrin repeats (many copies) VPS9 PF02204.18 OAG12870.1 - 7.4e-16 58.3 0.0 1.7e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 OAG12870.1 - 5.6e-14 52.5 0.0 7.7e-05 23.2 0.0 4.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG12870.1 - 4.2e-07 30.4 0.1 0.27 11.9 0.0 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG12870.1 - 3.2e-06 27.1 0.0 0.27 11.9 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.24 OAG12870.1 - 0.00066 19.6 0.0 0.0022 18.0 0.0 1.9 1 0 0 1 1 1 1 PX domain Ank PF00023.30 OAG12870.1 - 0.0024 18.3 0.0 4 8.1 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat T4SS PF07996.11 OAG12870.1 - 0.031 14.7 0.4 0.12 12.8 0.1 2.1 2 1 0 2 2 2 0 Type IV secretion system proteins DIRP PF06584.13 OAG12870.1 - 0.64 10.2 2.4 0.54 10.5 0.3 2.0 2 0 0 2 2 2 0 DIRP bZIP_1 PF00170.21 OAG12871.1 - 6.3e-06 26.2 1.5 1.2e-05 25.3 1.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG12871.1 - 0.0004 20.4 5.0 0.00079 19.5 5.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG12871.1 - 0.012 16.2 2.6 0.024 15.1 2.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor LCE PF14672.6 OAG12871.1 - 0.015 15.8 1.8 0.88 10.2 0.1 2.9 2 0 0 2 2 2 0 Late cornified envelope DivIC PF04977.15 OAG12871.1 - 0.17 11.6 1.1 0.32 10.8 1.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Rbsn PF11464.8 OAG12871.1 - 0.26 11.1 0.3 0.51 10.1 0.3 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain CIA30 PF08547.12 OAG12875.1 - 1.8e-39 135.3 0.4 2.2e-39 135.0 0.4 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Receptor_2B4 PF11465.8 OAG12875.1 - 0.0089 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 DUF202 PF02656.15 OAG12876.1 - 7e-17 61.6 5.1 9.8e-17 61.2 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4149 PF13664.6 OAG12876.1 - 0.045 14.1 3.0 0.087 13.2 3.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) COX4_pro_2 PF07835.12 OAG12876.1 - 0.047 13.8 3.8 0.25 11.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV RPA_C PF08784.11 OAG12877.1 - 3.2e-17 63.1 0.6 1e-16 61.5 0.1 2.1 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OAG12877.1 - 1.5e-09 37.7 0.0 3.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_36 PF13730.6 OAG12877.1 - 0.0051 16.7 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DEAD PF00270.29 OAG12878.1 - 2.7e-48 164.0 0.0 1.3e-47 161.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG12878.1 - 2.5e-25 89.0 0.0 1.8e-23 83.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OAG12878.1 - 4.7e-21 74.8 4.2 1.4e-20 73.3 4.2 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain AP2 PF00847.20 OAG12878.1 - 1.8 8.9 5.4 0.44 10.8 0.3 2.7 3 0 0 3 3 3 0 AP2 domain Zn_clus PF00172.18 OAG12879.1 - 0.00015 21.8 11.7 0.00022 21.3 11.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 OAG12879.1 - 0.0063 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAG12879.1 - 0.019 15.0 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 PAS fold DnaJ PF00226.31 OAG12880.1 - 1.3e-14 54.1 0.6 2.8e-14 53.0 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain Acyl-ACP_TE PF01643.17 OAG12880.1 - 0.044 13.1 3.6 0.061 12.6 3.6 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase DEAD PF00270.29 OAG12881.1 - 1.6e-47 161.5 0.0 3.4e-47 160.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG12881.1 - 3.4e-24 85.3 0.0 1.3e-23 83.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG12881.1 - 2.7e-19 69.1 0.4 6.4e-19 67.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) CMS1 PF14617.6 OAG12881.1 - 0.037 13.4 0.0 0.037 13.4 0.0 4.0 5 0 0 5 5 5 0 U3-containing 90S pre-ribosomal complex subunit Bac_RepA_C PF18008.1 OAG12881.1 - 0.15 12.4 0.4 0.43 11.0 0.4 1.8 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain FSH1 PF03959.13 OAG12881.1 - 0.48 10.0 2.5 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PT PF04886.12 OAG12882.1 - 0.17 11.4 3.2 0.25 10.9 1.8 2.0 2 0 0 2 2 2 0 PT repeat Glycoprotein_G PF00802.19 OAG12882.1 - 4.7 6.5 22.8 11 5.4 22.8 1.6 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DUF2828 PF11443.8 OAG12882.1 - 9.6 4.2 9.1 16 3.4 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3632 PF12311.8 OAG12883.1 - 1.4e-20 74.5 0.2 2.2e-20 73.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF2281 PF10047.9 OAG12883.1 - 0.0099 16.6 0.0 0.024 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2281) DUF3337 PF11816.8 OAG12884.1 - 2e-59 200.3 0.0 4.2e-59 199.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 OAG12884.1 - 7.2e-16 58.3 15.6 0.00016 22.4 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 OAG12884.1 - 0.0029 16.3 0.4 0.0075 15.0 0.4 1.6 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAG12884.1 - 0.11 12.8 0.1 1 9.7 0.1 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Myb_Cef PF11831.8 OAG12886.1 - 9.8e-53 179.2 7.3 9.8e-53 179.2 7.3 3.0 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 OAG12886.1 - 1.7e-19 69.7 5.3 1.2e-09 38.1 1.8 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG12886.1 - 8.3e-16 58.0 3.7 1.6e-10 41.0 2.8 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain NAD_binding_2 PF03446.15 OAG12888.1 - 3.7e-26 92.2 0.0 5.4e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG12888.1 - 1.3e-09 38.3 0.1 2.4e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG12888.1 - 2e-06 28.3 0.0 5.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAG12888.1 - 2.5e-05 24.4 0.1 6.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAG12888.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.17 OAG12888.1 - 0.072 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase DNA_pol_B_palm PF14792.6 OAG12889.1 - 1.2e-31 109.2 0.0 2.5e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 OAG12889.1 - 4.1e-25 87.7 0.1 8.2e-25 86.8 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 OAG12889.1 - 9.5e-19 67.0 0.3 2.4e-18 65.7 0.3 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OAG12889.1 - 1.1e-16 60.9 0.2 2.2e-16 59.9 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain PTCB-BRCT PF12738.7 OAG12889.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Glyco_hydro_16 PF00722.21 OAG12890.1 - 2.5e-08 33.6 4.9 4.1e-08 32.9 4.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_M49 PF03571.15 OAG12891.1 - 4.8e-243 807.5 0.0 5.7e-243 807.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 TPR_8 PF13181.6 OAG12891.1 - 0.18 12.1 2.5 0.7 10.3 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Mannitol_dh_C PF08125.13 OAG12892.1 - 3.1e-79 265.9 0.0 4.9e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 OAG12892.1 - 1.1e-41 142.5 0.0 1.6e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain DNA_RNApol_7kD PF03604.13 OAG12893.1 - 1.3e-17 63.2 6.2 1.6e-17 62.9 6.2 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 OAG12893.1 - 0.00019 21.4 0.2 0.0002 21.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OAG12893.1 - 0.0067 16.4 0.3 0.0081 16.2 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_13 PF09855.9 OAG12893.1 - 0.0083 16.3 0.2 0.016 15.4 0.2 1.6 1 1 1 2 2 2 1 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF2318 PF10080.9 OAG12893.1 - 0.042 14.0 0.3 0.044 13.9 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) MCM_OB PF17207.3 OAG12893.1 - 0.058 13.2 0.1 0.061 13.2 0.1 1.1 1 0 0 1 1 1 0 MCM OB domain DUF951 PF06107.11 OAG12893.1 - 0.13 12.1 1.3 0.46 10.4 0.3 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) Zn-ribbon_8 PF09723.10 OAG12893.1 - 1 9.5 4.8 4.2 7.6 4.8 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Pkinase PF00069.25 OAG12894.1 - 8.6e-60 202.3 0.0 1e-58 198.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG12894.1 - 8.5e-26 90.8 0.1 1e-20 74.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG12894.1 - 3.2e-05 23.0 0.1 4.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG12894.1 - 0.00054 19.9 0.1 0.041 13.8 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG12894.1 - 0.00059 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG12894.1 - 0.009 15.4 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OAG12894.1 - 0.072 12.7 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase_C PF00433.24 OAG12894.1 - 0.077 13.7 0.0 0.21 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain TFIIA PF03153.13 OAG12894.1 - 8.2 6.3 12.8 12 5.7 12.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Filament PF00038.21 OAG12895.1 - 0.00018 21.2 42.6 0.00018 21.2 42.6 5.1 3 2 0 3 3 3 2 Intermediate filament protein CLZ PF16526.5 OAG12895.1 - 0.013 15.9 0.7 0.013 15.9 0.7 9.0 7 2 5 12 12 12 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mod_r PF07200.13 OAG12896.1 - 5.4e-31 107.7 2.1 6.8e-31 107.4 2.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TFIIA PF03153.13 OAG12896.1 - 0.72 9.8 7.8 0.96 9.4 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 OAG12896.1 - 4 5.9 8.6 5 5.5 8.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Methyltransf_31 PF13847.6 OAG12898.1 - 8.7e-05 22.4 0.0 0.00027 20.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG12898.1 - 0.0029 18.3 0.0 0.0062 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG12898.1 - 0.0035 18.0 0.0 0.0074 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RGCC PF15151.6 OAG12898.1 - 0.017 15.3 0.8 0.017 15.3 0.8 1.9 2 0 0 2 2 2 0 Response gene to complement 32 protein family Ubie_methyltran PF01209.18 OAG12898.1 - 0.027 13.8 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG12898.1 - 0.17 12.6 0.0 0.41 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 OAG12900.1 - 2.6e-50 171.5 0.0 3.7e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hydantoinase_B PF02538.14 OAG12901.1 - 6.4e-41 140.3 5.6 1.6e-35 122.5 0.5 2.0 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase DUF3605 PF12239.8 OAG12902.1 - 3.2e-51 173.7 2.6 4e-51 173.4 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Aldo_ket_red PF00248.21 OAG12904.1 - 4.4e-51 173.8 0.0 9.1e-51 172.8 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family PFO_beta_C PF12367.8 OAG12904.1 - 0.012 15.8 0.3 7.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DUF1848 PF08902.11 OAG12904.1 - 0.053 13.2 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) SLT PF01464.20 OAG12905.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Polysacc_deac_1 PF01522.21 OAG12906.1 - 7.1e-28 97.0 0.0 1.2e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 OAG12906.1 - 4.3e-23 81.5 72.0 1e-09 38.7 15.9 3.5 3 0 0 3 3 3 3 Chitin recognition protein UBA PF00627.31 OAG12907.1 - 0.00057 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain AT_hook PF02178.19 OAG12907.1 - 0.77 9.8 7.9 3.2 7.9 7.9 2.1 1 0 0 1 1 1 0 AT hook motif XAP5 PF04921.14 OAG12908.1 - 3.5e-86 289.1 0.0 4.6e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator GAGA_bind PF06217.12 OAG12908.1 - 0.034 14.4 0.1 0.05 13.9 0.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family WG_beta_rep PF14903.6 OAG12908.1 - 0.14 12.4 0.5 16 5.9 0.1 2.6 2 0 0 2 2 2 0 WG containing repeat GDPD PF03009.17 OAG12909.1 - 1.5e-69 234.6 0.0 2.7e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 OAG12909.1 - 5.5e-28 97.4 0.0 7.9e-10 39.2 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG12909.1 - 5.3e-25 87.5 0.1 1.3e-09 38.4 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) SPX PF03105.19 OAG12909.1 - 9e-23 81.8 10.3 3.6e-12 46.9 0.0 3.7 2 1 2 4 4 4 3 SPX domain Ank_5 PF13857.6 OAG12909.1 - 8.6e-20 70.6 0.1 1.4e-06 28.5 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG12909.1 - 1.6e-19 68.0 0.7 9.5e-06 25.6 0.0 7.1 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OAG12909.1 - 2.8e-18 65.4 4.0 0.00011 22.5 0.0 6.7 5 1 0 5 5 5 4 Ankyrin repeat RGCC PF15151.6 OAG12909.1 - 0.065 13.5 0.0 0.28 11.4 0.0 2.1 1 0 0 1 1 1 0 Response gene to complement 32 protein family YadA_anchor PF03895.15 OAG12910.1 - 0.12 12.5 0.0 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 YadA-like membrane anchor domain Glyco_hydro_88 PF07470.13 OAG12911.1 - 4.4e-67 226.6 6.5 5.3e-67 226.3 6.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fox-1_C PF12414.8 OAG12911.1 - 0.1 13.0 0.7 1.2 9.6 0.1 2.6 2 0 0 2 2 2 0 Calcitonin gene-related peptide regulator C terminal Ribosomal_S14 PF00253.21 OAG12913.1 - 2.6e-13 49.5 0.3 3.7e-13 49.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e SET PF00856.28 OAG12914.1 - 0.69 10.3 5.0 0.77 10.1 0.0 2.6 2 1 0 2 2 2 0 SET domain MFS_1 PF07690.16 OAG12916.1 - 3.7e-12 45.9 30.2 1e-11 44.4 8.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAG12916.1 - 0.006 16.1 4.7 0.006 16.1 4.7 2.2 2 0 0 2 2 2 1 Nodulin-like 7tm_7 PF08395.12 OAG12916.1 - 0.26 10.5 4.8 0.52 9.5 0.2 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor RNase_PH PF01138.21 OAG12917.1 - 2.1e-17 63.9 0.0 4.5e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Toast_rack_N PF17115.5 OAG12917.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of toast_rack, DUF2154 SSF PF00474.17 OAG12919.1 - 1.8e-24 86.4 30.3 2.5e-24 85.9 30.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Amino_oxidase PF01593.24 OAG12923.1 - 4.9e-14 52.5 0.0 1e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG12923.1 - 3.7e-13 49.5 0.0 7.6e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG12923.1 - 2.2e-06 27.2 0.1 3.8e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG12923.1 - 8.6e-06 25.2 0.1 1.4e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG12923.1 - 2.8e-05 23.0 0.9 5.6e-05 22.0 0.9 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG12923.1 - 3.6e-05 23.0 0.1 6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG12923.1 - 6.3e-05 22.4 0.1 9.7e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG12923.1 - 0.00024 20.4 0.2 0.00039 19.7 0.2 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG12923.1 - 0.00093 18.6 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAG12923.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG12923.1 - 0.051 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG12923.1 - 0.078 12.0 0.7 0.13 11.3 0.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG12923.1 - 0.11 11.5 0.4 0.16 10.9 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG12923.1 - 0.16 12.0 0.1 0.51 10.3 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4393 PF14337.6 OAG12923.1 - 0.2 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) RVT_1 PF00078.27 OAG12924.1 - 0.00031 20.3 0.0 0.00068 19.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_Ag35 PF03286.14 OAG12924.1 - 0.018 14.8 8.3 0.023 14.5 6.3 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nucleo_P87 PF07267.11 OAG12924.1 - 3.5 6.4 5.9 5.5 5.7 5.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NUDIX PF00293.28 OAG12925.1 - 2.7e-09 37.2 0.0 3.6e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain GST_N_3 PF13417.6 OAG12926.1 - 6.4e-07 29.7 0.0 1.9e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG12926.1 - 9.9e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG12926.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG12926.1 - 8.1e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG12926.1 - 0.00023 21.3 0.0 0.00033 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG12926.1 - 0.002 18.7 0.0 0.0043 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain His_Phos_2 PF00328.22 OAG12928.1 - 4.3e-11 42.8 0.0 1.3e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Phage_Coat_B PF05356.11 OAG12928.1 - 0.019 14.8 0.2 0.043 13.7 0.2 1.5 1 0 0 1 1 1 0 Phage Coat protein B Citrate_synt PF00285.21 OAG12930.1 - 1.6e-20 73.5 0.0 5.8e-17 61.8 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 OAG12930.1 - 3.6e-19 69.3 0.0 8.1e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 OAG12930.1 - 6.2e-14 52.1 0.4 1.2e-13 51.2 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAG12930.1 - 9e-05 22.3 0.0 0.0006 19.6 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 OAG12931.1 - 1.1e-87 292.1 0.1 1.5e-87 291.7 0.1 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 OAG12931.1 - 6.1e-08 32.5 0.0 9.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain TPR_12 PF13424.6 OAG12932.1 - 1e-47 160.3 11.9 1.7e-16 60.2 0.7 4.8 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG12932.1 - 2.5e-46 154.3 10.4 5e-10 38.9 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 OAG12932.1 - 2.3e-22 77.8 18.1 1.7e-05 24.4 0.1 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAG12932.1 - 9e-19 66.1 9.8 0.00041 20.3 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAG12932.1 - 2.7e-17 62.0 12.0 0.013 16.2 0.1 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG12932.1 - 3e-16 58.2 18.3 0.011 15.8 0.1 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG12932.1 - 6.8e-16 58.6 7.5 5.7e-12 45.6 2.0 2.7 2 1 1 3 3 2 2 MalT-like TPR region TPR_7 PF13176.6 OAG12932.1 - 7.7e-14 50.6 15.7 0.001 18.9 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.22 OAG12932.1 - 4e-10 39.3 0.1 7e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 OAG12932.1 - 8.9e-08 32.5 13.2 0.0033 17.9 1.4 5.3 4 1 1 5 5 4 3 Tetratricopeptide repeat PPR PF01535.20 OAG12932.1 - 2.6e-06 27.3 2.1 7.3 7.1 0.0 6.0 5 0 0 5 5 5 0 PPR repeat RPN7 PF10602.9 OAG12932.1 - 5.3e-06 26.3 1.6 0.19 11.4 0.0 3.4 3 0 0 3 3 3 2 26S proteasome subunit RPN7 DUF2225 PF09986.9 OAG12932.1 - 5.9e-05 22.9 2.9 0.034 13.9 0.3 3.2 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 OAG12932.1 - 6.4e-05 23.2 0.3 3.7 8.5 0.0 4.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG12932.1 - 9.2e-05 23.0 24.8 1.1 10.0 0.0 6.9 7 1 0 7 7 6 3 Tetratricopeptide repeat SNAP PF14938.6 OAG12932.1 - 0.00013 21.6 0.1 0.0021 17.5 0.0 2.3 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP AAA_16 PF13191.6 OAG12932.1 - 0.00013 22.4 0.5 0.00057 20.3 0.5 2.1 1 1 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 OAG12932.1 - 0.00084 19.6 4.9 6.6 7.3 0.1 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 OAG12932.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF5344 PF17279.2 OAG12932.1 - 0.013 16.1 0.3 34 5.1 0.0 4.2 2 1 1 4 4 3 0 Family of unknown function (DUF5344) ATP-synt_D PF01813.17 OAG12932.1 - 0.025 14.4 0.0 0.46 10.3 0.0 2.6 1 1 0 2 2 2 0 ATP synthase subunit D TPR_21 PF09976.9 OAG12932.1 - 0.027 14.2 11.2 4.8 6.8 0.2 4.5 1 1 2 4 4 4 0 Tetratricopeptide repeat-like domain TAtT PF16811.5 OAG12932.1 - 0.029 13.7 1.6 0.11 11.8 0.2 2.4 1 1 1 3 3 3 0 TRAP transporter T-component AAA_22 PF13401.6 OAG12932.1 - 0.043 14.1 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.6 OAG12932.1 - 0.072 12.8 12.1 0.89 9.3 0.1 5.0 5 0 0 5 5 5 0 TPR repeat DUF3726 PF12525.8 OAG12932.1 - 0.074 13.2 0.5 15 5.8 0.0 4.4 7 0 0 7 7 3 0 Protein of unknown function (DUF3726) TniB PF05621.11 OAG12932.1 - 0.081 12.3 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 OAG12932.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OAG12932.1 - 0.12 11.9 0.0 0.4 10.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG12932.1 - 0.14 12.1 0.2 0.59 10.0 0.2 1.9 1 1 0 1 1 1 0 NACHT domain Peptidase_M13 PF01431.21 OAG12932.1 - 0.18 11.4 0.1 0.57 9.7 0.1 1.8 1 1 1 2 2 2 0 Peptidase family M13 TPR_6 PF13174.6 OAG12932.1 - 0.28 11.9 24.5 6.4 7.6 0.3 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 OAG12932.1 - 0.65 10.6 4.6 58 4.3 0.2 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4810) DUF4652 PF15525.6 OAG12933.1 - 0.037 13.8 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Hydrolase_4 PF12146.8 OAG12933.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Arrestin_N PF00339.29 OAG12935.1 - 5.6e-07 29.7 0.2 1.4e-05 25.2 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CBFD_NFYB_HMF PF00808.23 OAG12936.1 - 2.1e-10 40.7 0.0 4.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG12936.1 - 0.0001 22.7 2.6 0.00059 20.2 0.0 2.5 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAG12936.1 - 0.00075 19.6 0.2 0.0011 19.1 0.2 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF5358 PF17311.2 OAG12936.1 - 0.022 14.8 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5358) BUD22 PF09073.10 OAG12936.1 - 0.063 12.6 16.7 0.067 12.5 16.7 1.2 1 0 0 1 1 1 0 BUD22 Bromo_TP PF07524.13 OAG12936.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Hid1 PF12722.7 OAG12936.1 - 0.61 8.1 7.6 0.73 7.9 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 OAG12936.1 - 0.91 9.4 16.8 1 9.3 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUZ PF12752.7 OAG12938.1 - 2.9e-06 27.9 6.3 2.9e-06 27.9 6.3 4.0 4 0 0 4 4 4 1 SUZ domain eIF3_subunit PF08597.10 OAG12938.1 - 0.44 10.4 18.0 1 9.3 4.7 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit FAD_binding_3 PF01494.19 OAG12941.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain UPF0242 PF06785.11 OAG12942.1 - 0.005 17.0 5.4 0.005 17.0 5.4 3.7 1 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 OAG12942.1 - 0.13 12.3 41.2 2.4 8.1 6.2 3.6 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion KxDL PF10241.9 OAG12942.1 - 2.6 8.4 26.3 0.078 13.3 2.1 4.9 3 2 2 5 5 5 0 Uncharacterized conserved protein RasGAP_C PF03836.15 OAG12942.1 - 8.8 6.5 33.8 0.061 13.5 3.3 4.1 3 1 2 5 5 5 0 RasGAP C-terminus GMC_oxred_N PF00732.19 OAG12943.1 - 5.8e-66 222.9 0.1 1.7e-65 221.3 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG12943.1 - 4.1e-35 121.4 0.3 7.3e-35 120.6 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG12943.1 - 8.5e-07 28.4 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG12943.1 - 0.00062 19.5 0.2 0.042 13.4 0.0 3.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG12943.1 - 0.00098 19.3 0.0 0.0035 17.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG12943.1 - 0.0036 16.6 0.2 0.88 8.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG12943.1 - 0.0048 17.4 0.1 0.85 10.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG12943.1 - 0.0075 15.4 0.1 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG12943.1 - 0.092 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family PHD PF00628.29 OAG12944.1 - 1.1e-05 25.3 9.6 2.3e-05 24.2 9.6 1.6 1 0 0 1 1 1 1 PHD-finger Mitofilin PF09731.9 OAG12944.1 - 0.98 8.2 28.3 1.5 7.5 28.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PHD_2 PF13831.6 OAG12944.1 - 1.5 8.4 7.5 0.11 12.1 2.0 1.9 2 0 0 2 2 2 0 PHD-finger Ion_trans PF00520.31 OAG12945.1 - 1.8e-128 426.9 72.9 4.9e-40 137.3 1.5 4.7 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 OAG12945.1 - 0.00018 21.2 0.0 0.00041 20.0 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 OAG12945.1 - 0.00043 19.6 0.0 0.0011 18.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG12945.1 - 0.0023 17.8 0.0 0.0099 15.7 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain PKD_channel PF08016.12 OAG12945.1 - 0.036 12.8 56.8 0.6 8.7 10.1 6.9 6 1 0 6 6 6 0 Polycystin cation channel EF-hand_7 PF13499.6 OAG12945.1 - 0.041 14.3 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair KAR9 PF08580.10 OAG12946.1 - 1.3 7.5 4.4 1.3 7.4 4.4 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 EHN PF06441.12 OAG12948.1 - 8.4e-35 119.4 1.3 7.5e-34 116.4 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG12948.1 - 2.7e-09 37.1 0.1 4.6e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG12948.1 - 0.017 15.7 5.8 0.057 14.0 5.8 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family CBM_19 PF03427.13 OAG12949.1 - 0.00053 19.9 8.3 0.00053 19.9 8.3 3.3 2 1 0 3 3 3 1 Carbohydrate binding domain (family 19) Glyco_hydro_61 PF03443.14 OAG12949.1 - 0.0028 17.6 0.0 0.0066 16.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SNF5 PF04855.12 OAG12950.1 - 3.7e-85 285.5 0.0 4.8e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 OAG12950.1 - 0.0039 16.8 0.2 0.012 15.2 0.2 1.8 1 0 0 1 1 1 1 GATA zinc finger Spt20 PF12090.8 OAG12951.1 - 0.12 11.9 13.5 0.054 13.1 8.7 2.3 2 1 1 3 3 3 0 Spt20 family TFIIA PF03153.13 OAG12951.1 - 0.13 12.2 14.2 0.16 12.0 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 OAG12951.1 - 0.14 13.1 1.1 0.43 11.6 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 OAG12951.1 - 0.26 10.4 4.5 0.35 9.9 4.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Androgen_recep PF02166.16 OAG12951.1 - 0.49 9.2 10.5 1.1 8.0 10.5 1.6 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 OAG12953.1 - 7.3 7.6 7.3 8.8 7.4 2.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SURF4 PF02077.15 OAG12955.1 - 1.1e-95 320.3 6.7 1.2e-95 320.1 6.7 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 OAG12955.1 - 0.36 10.8 6.7 0.081 12.9 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1405) HR_lesion PF05514.11 OAG12955.1 - 2.5 8.3 8.9 0.96 9.6 1.9 2.8 2 1 0 3 3 3 0 HR-like lesion-inducing DoxX PF07681.12 OAG12955.1 - 2.8 8.6 20.3 2.4 8.8 0.1 3.7 3 2 0 3 3 3 0 DoxX IU_nuc_hydro PF01156.19 OAG12956.1 - 8.7e-57 193.0 0.0 1.9e-56 191.9 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.16 OAG12957.1 - 1.9e-38 132.3 43.7 5.3e-38 130.9 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG12957.1 - 0.013 13.9 3.4 0.02 13.3 3.4 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Acetyltransf_10 PF13673.7 OAG12958.1 - 1.7e-07 31.2 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG12958.1 - 7.1e-06 26.4 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG12958.1 - 0.00023 21.4 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ABM PF03992.16 OAG12959.1 - 0.00021 21.3 0.6 0.0016 18.5 0.1 2.1 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Fungal_trans_2 PF11951.8 OAG12960.1 - 3.9e-12 45.7 7.1 5.9e-12 45.1 7.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG12960.1 - 5e-09 36.1 10.3 8.7e-09 35.4 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nebulin PF00880.18 OAG12960.1 - 0.014 15.3 0.2 0.03 14.2 0.2 1.6 1 0 0 1 1 1 0 Nebulin repeat DHO_dh PF01180.21 OAG12961.1 - 1.1e-22 80.7 0.3 9.2e-22 77.6 0.3 1.9 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 OAG12961.1 - 0.6 9.4 3.3 0.93 8.8 3.3 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Inhibitor_I78 PF11720.8 OAG12963.1 - 1.2e-08 34.9 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 OAG12963.1 - 0.00058 20.5 0.0 0.00066 20.3 0.0 1.1 1 0 0 1 1 1 1 Potato inhibitor I family DUF3632 PF12311.8 OAG12964.1 - 2.9e-14 53.9 0.0 3.1e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Bradykinin PF06753.12 OAG12964.1 - 0.17 11.6 0.5 0.28 10.9 0.5 1.3 1 0 0 1 1 1 0 Bradykinin AltA1 PF16541.5 OAG12966.1 - 0.026 15.4 0.3 0.036 14.9 0.3 1.2 1 0 0 1 1 1 0 Alternaria alternata allergen 1 HARP PF07443.13 OAG12966.1 - 0.13 11.9 0.2 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 HepA-related protein (HARP) RNase_H PF00075.24 OAG12967.1 - 0.004 17.3 0.1 0.07 13.3 0.1 2.0 1 1 0 1 1 1 1 RNase H Cys_box PF17869.1 OAG12967.1 - 0.089 12.9 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Anosmin cysteine rich domain Mito_carr PF00153.27 OAG12969.1 - 8.6e-47 157.0 3.9 9.6e-18 63.9 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG12969.1 - 0.012 14.8 0.1 0.29 10.2 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease WD40 PF00400.32 OAG12970.1 - 5.8e-06 26.9 3.3 9.7 7.2 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG12970.1 - 5.4e-05 23.4 0.0 0.1 12.9 0.0 3.5 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 OAG12970.1 - 7.2e-05 22.2 0.0 0.0073 15.6 0.0 2.9 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 OAG12970.1 - 0.014 15.0 0.0 7.7 6.0 0.0 2.8 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region MMS1_N PF10433.9 OAG12970.1 - 0.17 10.5 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1688 PF07958.11 OAG12971.1 - 7.2e-173 575.1 0.0 8.1e-173 575.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 OAG12971.1 - 0.00011 21.9 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family SRR1 PF07985.12 OAG12972.1 - 1e-06 28.7 0.0 2.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 SRR1 Glyoxalase PF00903.25 OAG12973.1 - 0.00028 21.1 0.0 0.00032 20.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5-FTHF_cyc-lig PF01812.20 OAG12974.1 - 0.013 15.4 0.2 0.047 13.5 0.2 2.0 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family GPHR_N PF12537.8 OAG12974.1 - 0.054 13.6 0.0 0.28 11.3 0.0 2.3 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal DUF4266 PF14086.6 OAG12974.1 - 2 9.4 6.0 34 5.5 0.3 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) DASH_Duo1 PF08651.10 OAG12974.1 - 2.5 8.0 6.1 0.48 10.2 1.1 2.5 3 0 0 3 3 3 0 DASH complex subunit Duo1 MFS_1 PF07690.16 OAG12975.1 - 1.8e-26 92.9 58.6 1.1e-14 54.1 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG12975.1 - 0.00042 19.0 12.8 0.00042 19.0 12.8 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein FAA_hydrolase PF01557.18 OAG12976.1 - 9.4e-64 215.1 0.0 1.3e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hydrolase_4 PF12146.8 OAG12976.1 - 1e-18 67.5 0.0 1.8e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG12976.1 - 1.9e-17 63.8 0.0 3.2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG12976.1 - 1.1e-12 49.0 0.1 1.6e-12 48.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OAG12976.1 - 0.00055 19.6 0.1 0.00096 18.9 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 OAG12976.1 - 0.0056 15.4 0.0 0.009 14.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family La PF05383.17 OAG12978.1 - 1.8e-17 63.1 0.7 3.2e-17 62.3 0.7 1.4 1 0 0 1 1 1 1 La domain DUF3808 PF10300.9 OAG12979.1 - 1.5e-144 482.3 0.1 1.9e-144 482.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF4823 PF16105.5 OAG12979.1 - 0.092 12.6 0.2 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4823) TPR_6 PF13174.6 OAG12979.1 - 0.8 10.5 5.4 16 6.4 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG12979.1 - 2.6 8.6 6.2 2.4 8.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.13 OAG12980.1 - 6.1e-23 80.6 15.1 8.6e-23 80.2 15.1 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.19 OAG12981.1 - 1.3e-152 508.2 1.8 1.4e-152 508.0 1.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 OAG12981.1 - 5.9e-05 23.0 0.2 0.009 16.0 0.0 3.2 3 1 0 3 3 3 1 PA domain DUF3530 PF12048.8 OAG12981.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) FIVAR PF07554.13 OAG12981.1 - 0.24 12.2 1.8 14 6.6 0.0 3.5 4 0 0 4 4 4 0 FIVAR domain Mpv17_PMP22 PF04117.12 OAG12982.1 - 6.5e-19 67.9 0.1 1.8e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family Vps26 PF03643.15 OAG12983.1 - 1.4e-129 430.9 0.8 1.7e-129 430.7 0.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OAG12983.1 - 0.0019 18.3 0.9 0.26 11.3 1.0 3.4 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SKI PF01202.22 OAG12984.1 - 5.8e-12 46.0 0.0 7.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 OAG12984.1 - 8.6e-11 42.5 0.0 1.6e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG12984.1 - 2.6e-09 37.4 0.0 3.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 OAG12984.1 - 1.1e-07 31.8 0.0 3.1e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 OAG12984.1 - 2e-07 31.1 0.0 4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 OAG12984.1 - 2.9e-07 31.0 0.0 6.4e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 OAG12984.1 - 4.8e-07 29.8 0.0 0.0016 18.3 0.0 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 OAG12984.1 - 1.5e-05 25.3 0.0 3.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG12984.1 - 5.5e-05 23.6 0.0 0.00012 22.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAG12984.1 - 0.0006 20.2 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OAG12984.1 - 0.00065 20.2 0.0 0.00088 19.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 OAG12984.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 OAG12984.1 - 0.0029 17.7 0.0 0.0041 17.2 0.0 1.5 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_28 PF13521.6 OAG12984.1 - 0.0032 17.7 0.0 0.0064 16.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OAG12984.1 - 0.0036 17.7 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 OAG12984.1 - 0.0036 17.2 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 1 NTPase DUF87 PF01935.17 OAG12984.1 - 0.0037 17.4 0.2 0.38 10.8 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain Cytidylate_kin2 PF13189.6 OAG12984.1 - 0.004 17.3 0.1 0.0094 16.1 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase-like family APS_kinase PF01583.20 OAG12984.1 - 0.0045 16.9 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase CoaE PF01121.20 OAG12984.1 - 0.0045 16.7 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_5 PF07728.14 OAG12984.1 - 0.0048 16.9 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Ploopntkinase1 PF18748.1 OAG12984.1 - 0.0049 16.4 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 Zeta_toxin PF06414.12 OAG12984.1 - 0.0061 15.9 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 OAG12984.1 - 0.0085 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 OAG12984.1 - 0.012 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 OAG12984.1 - 0.014 15.5 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 OAG12984.1 - 0.02 14.8 0.0 0.076 12.9 0.0 1.9 1 1 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 OAG12984.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAG12984.1 - 0.028 13.6 0.0 0.094 11.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 OAG12984.1 - 0.029 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 OAG12984.1 - 0.034 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_2 PF03668.15 OAG12984.1 - 0.045 13.0 0.0 0.66 9.2 0.0 2.2 1 1 0 1 1 1 0 P-loop ATPase protein family ADK PF00406.22 OAG12984.1 - 0.047 13.8 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Adenylate kinase PRK PF00485.18 OAG12984.1 - 0.047 13.4 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 OAG12984.1 - 0.051 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 OAG12984.1 - 0.063 12.8 0.1 0.28 10.7 0.0 2.1 2 1 1 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 OAG12984.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.17 OAG12984.1 - 0.07 12.8 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_23 PF13476.6 OAG12984.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.23 OAG12985.1 - 8.6e-75 251.2 0.1 1.8e-74 250.2 0.0 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG12985.1 - 2.1e-19 69.1 0.1 6.9e-19 67.5 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 OAG12985.1 - 9.2e-12 45.1 0.2 3e-11 43.5 0.1 2.0 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAG12985.1 - 0.033 14.0 0.0 0.91 9.4 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like ESCRT-II PF05871.12 OAG12986.1 - 1.7e-48 164.4 0.0 2.2e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit PPR_1 PF12854.7 OAG12986.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 PPR repeat RTT107_BRCT_5 PF16770.5 OAG12987.1 - 9.9e-23 79.9 0.0 3.9e-22 78.0 0.0 2.1 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 OAG12987.1 - 1.4e-22 79.4 0.6 5.5e-20 71.1 0.1 2.9 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 OAG12987.1 - 1.5e-15 57.3 0.8 3.2e-09 37.0 0.0 3.6 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG12987.1 - 4e-11 43.2 4.7 0.00045 20.6 0.1 4.7 5 1 0 5 5 5 2 BRCT domain, a BRCA1 C-terminus domain NIBRIN_BRCT_II PF16508.5 OAG12987.1 - 0.023 15.0 0.1 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein IBB PF01749.20 OAG12987.1 - 0.84 10.1 6.2 2.7 8.5 6.2 1.9 1 0 0 1 1 1 0 Importin beta binding domain Abhydrolase_6 PF12697.7 OAG12988.1 - 1.5e-08 35.5 0.1 3.1e-08 34.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG12988.1 - 3.8e-05 23.1 0.0 5.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG12988.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lant_dehydr_C PF14028.6 OAG12989.1 - 0.14 11.7 1.4 0.21 11.1 0.2 1.7 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Bac_luciferase PF00296.20 OAG12990.1 - 1.3e-71 241.6 0.0 1.5e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Peptidase_S9 PF00326.21 OAG12991.1 - 8.8e-12 44.9 0.6 1.1e-11 44.6 0.6 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAG12991.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 OAG12991.1 - 0.00023 20.9 0.3 0.00024 20.8 0.3 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 OAG12991.1 - 0.0039 17.1 0.0 0.0047 16.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG12991.1 - 0.0044 16.0 0.1 0.0055 15.6 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family PAE PF03283.13 OAG12991.1 - 0.073 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase SH3_13 PF18335.1 OAG12992.1 - 0.13 12.1 0.0 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain AMP-binding PF00501.28 OAG12993.1 - 6.1e-76 255.7 0.0 7.3e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG12993.1 - 8.5e-08 33.1 0.0 1.7e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GCV_T PF01571.21 OAG12994.1 - 1.6e-86 289.9 0.0 2.1e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OAG12994.1 - 6.8e-21 74.0 0.1 1.7e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.8 OAG12994.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) WW_FCH_linker PF16623.5 OAG12994.1 - 0.21 12.3 0.6 4.4 8.1 0.1 2.5 2 0 0 2 2 2 0 Unstructured linker region between on GAS7 protein V-ATPase_C PF03223.15 OAG12995.1 - 1.7e-126 422.5 0.1 2e-126 422.4 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Cep57_MT_bd PF06657.13 OAG12995.1 - 0.057 13.9 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Peroxidase_2 PF01328.17 OAG12998.1 - 2.2e-46 158.7 0.0 3.2e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 adh_short PF00106.25 OAG12999.1 - 1.1e-13 51.1 0.0 1.9e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG12999.1 - 1.2e-08 34.8 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG12999.1 - 7.3e-06 26.0 0.0 1.6e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG12999.1 - 0.00038 20.4 0.2 0.00077 19.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG12999.1 - 0.00068 19.2 0.0 0.00085 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_4 PF13637.6 OAG13000.1 - 5.7e-35 119.2 1.1 2.8e-09 37.3 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG13000.1 - 1e-34 119.0 0.1 4.2e-12 46.5 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG13000.1 - 6.5e-30 102.8 3.4 4.9e-10 39.5 0.1 5.3 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG13000.1 - 6.5e-30 99.8 0.3 0.00031 21.0 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 OAG13000.1 - 9.9e-26 89.0 2.4 8.4e-06 26.0 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.8 OAG13000.1 - 0.32 10.6 0.9 0.57 9.8 0.0 1.8 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal Metallophos PF00149.28 OAG13003.1 - 2.2e-33 116.5 0.0 9.9e-29 101.3 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OAG13003.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 OAG13003.1 - 0.14 12.4 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Smg4_UPF3 PF03467.15 OAG13004.1 - 1.2e-38 132.9 0.0 1.2e-38 132.9 0.0 3.3 3 1 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 OAG13004.1 - 2.4e-05 24.1 0.1 0.0001 22.1 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 OAG13005.1 - 4.3e-60 199.6 1.6 9.4e-22 76.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein MT-A70 PF05063.14 OAG13006.1 - 7.3e-32 110.6 0.0 1.1e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Cytochrom_B558a PF05038.13 OAG13013.1 - 0.26 10.9 1.3 2 7.9 0.7 2.7 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit F-box PF00646.33 OAG13014.1 - 0.026 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 F-box domain CN_hydrolase PF00795.22 OAG13015.1 - 1.1e-51 175.7 0.0 1.2e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TMF_TATA_bd PF12325.8 OAG13016.1 - 1.2e-36 125.4 16.0 1.2e-36 125.4 16.0 7.1 2 1 4 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OAG13016.1 - 3.8e-23 81.3 12.4 3.8e-23 81.3 12.4 8.8 6 3 2 8 8 8 1 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 OAG13016.1 - 0.0069 16.4 1.9 0.0069 16.4 1.9 5.9 3 3 2 5 5 5 2 Protein of unknown function (DUF1664) DUF4472 PF14739.6 OAG13016.1 - 0.0086 16.8 8.8 0.0086 16.8 8.8 8.3 3 2 5 9 9 9 2 Domain of unknown function (DUF4472) SET PF00856.28 OAG13017.1 - 6.7e-20 72.2 0.0 1.5e-19 71.0 0.0 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 OAG13017.1 - 3.1e-14 53.6 2.6 3.1e-14 53.6 2.6 2.1 2 1 0 2 2 2 1 Pre-SET motif GrpB PF04229.14 OAG13018.1 - 1e-10 42.0 0.0 1e-10 42.0 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Nop52 PF05997.12 OAG13019.1 - 9.2e-66 221.7 0.1 1.1e-65 221.5 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 OAG13019.1 - 0.033 14.3 0.1 0.082 13.0 0.1 1.6 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Methyltransf_4 PF02390.17 OAG13020.1 - 2.8e-48 163.6 0.0 3.6e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OAG13020.1 - 0.00052 20.7 0.0 0.0012 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG13020.1 - 0.0019 18.0 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG13020.1 - 0.012 16.3 0.0 0.025 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Transketolase_N PF00456.21 OAG13020.1 - 0.038 12.9 0.0 0.081 11.9 0.0 1.5 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain Methyltransf_11 PF08241.12 OAG13020.1 - 0.093 13.4 0.0 0.28 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAG13020.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Vac_ImportDeg PF09783.9 OAG13021.1 - 9.3e-68 227.1 1.2 1.1e-67 226.8 1.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 OAG13022.1 - 6e-73 243.6 0.4 6.8e-73 243.5 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 OAG13023.1 - 2.1e-90 303.8 1.9 4.3e-90 302.8 1.9 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 OAG13023.1 - 3.4e-58 195.5 0.4 7.7e-58 194.4 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 OAG13023.1 - 6.6e-57 191.0 0.0 1.7e-56 189.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 OAG13023.1 - 9.6e-10 38.7 7.3 3.2e-09 37.1 0.1 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG13023.1 - 1.7e-08 34.7 3.8 0.00049 20.4 0.0 4.9 2 2 2 4 4 4 3 HEAT repeats Coatomer_g_Cpla PF16381.5 OAG13023.1 - 0.00019 21.6 0.0 0.00078 19.6 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 OAG13023.1 - 0.00029 20.8 0.8 0.69 10.3 0.0 5.0 6 0 0 6 6 5 1 HEAT repeat HEAT_EZ PF13513.6 OAG13023.1 - 0.0014 19.0 1.6 0.58 10.7 0.1 4.6 3 1 1 4 4 4 1 HEAT-like repeat AP4E_app_platf PF14807.6 OAG13023.1 - 0.028 14.8 0.2 0.095 13.1 0.2 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform RAG2 PF03089.14 OAG13023.1 - 0.14 11.2 0.2 0.26 10.2 0.2 1.4 1 0 0 1 1 1 0 Recombination activating protein 2 Gly_acyl_tr_N PF06021.11 OAG13023.1 - 0.23 11.6 1.8 0.97 9.5 0.5 2.3 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase DAGK_cat PF00781.24 OAG13024.1 - 1.4e-22 79.7 0.1 2.2e-22 79.0 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SGL PF08450.12 OAG13025.1 - 0.00043 20.0 0.3 0.12 12.0 0.1 2.5 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region GSDH PF07995.11 OAG13025.1 - 0.0053 16.1 0.5 0.042 13.2 0.5 2.3 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase WD40 PF00400.32 OAG13025.1 - 0.015 16.1 0.7 9.9 7.2 0.1 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat AflR PF08493.10 OAG13027.1 - 4e-15 56.1 5.7 7.2e-15 55.2 5.7 1.5 1 0 0 1 1 1 1 Aflatoxin regulatory protein Cytochrom_C_2 PF01322.20 OAG13027.1 - 0.12 13.3 0.0 0.24 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C' PUF PF00806.19 OAG13027.1 - 0.2 11.4 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat AveC_like PF17198.4 OAG13028.1 - 0.02 14.4 0.1 0.026 14.0 0.1 1.1 1 0 0 1 1 1 0 Spirocyclase AveC-like MutS_V PF00488.21 OAG13030.1 - 4.3e-47 160.6 0.1 8.8e-47 159.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG13030.1 - 5.5e-20 72.4 0.1 1.5e-19 71.0 0.0 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OAG13030.1 - 0.016 15.5 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV AAA_22 PF13401.6 OAG13030.1 - 0.054 13.8 0.3 0.53 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OAG13030.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF5375 PF17345.2 OAG13030.1 - 0.12 12.2 0.1 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5375) AAA_2 PF07724.14 OAG13031.1 - 1.6e-49 168.3 0.0 6.2e-46 156.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAG13031.1 - 2.4e-36 123.8 0.7 2.4e-36 123.8 0.7 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 OAG13031.1 - 3.9e-26 90.9 0.2 3.9e-26 90.9 0.2 2.6 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OAG13031.1 - 3.8e-21 75.9 1.4 1.6e-12 48.0 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG13031.1 - 1.3e-14 54.4 0.1 1.4e-08 34.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAG13031.1 - 3.1e-10 40.0 0.7 4.2e-05 23.3 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 OAG13031.1 - 2.6e-09 37.7 3.6 9.3e-05 22.9 0.1 4.0 3 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG13031.1 - 3.9e-08 33.7 2.1 0.011 16.0 0.0 4.0 3 2 0 3 3 2 2 AAA domain TniB PF05621.11 OAG13031.1 - 4.8e-07 29.4 0.1 0.0018 17.7 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 OAG13031.1 - 1.3e-06 27.9 0.1 0.033 13.6 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAG13031.1 - 1.5e-06 28.1 0.4 0.0019 18.0 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 OAG13031.1 - 1.8e-06 28.0 1.6 0.013 15.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 OAG13031.1 - 7.5e-06 25.6 0.0 0.05 13.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 OAG13031.1 - 1.5e-05 25.6 6.2 0.056 14.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 OAG13031.1 - 4.5e-05 23.4 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 OAG13031.1 - 6.9e-05 23.1 7.4 0.0068 16.7 0.0 4.7 5 1 0 5 5 4 1 AAA domain ATPase_2 PF01637.18 OAG13031.1 - 8e-05 22.7 3.9 0.44 10.4 0.2 4.1 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAG13031.1 - 0.00023 21.5 0.1 1.6 9.2 0.0 3.2 3 0 0 3 3 2 2 RNA helicase AAA_30 PF13604.6 OAG13031.1 - 0.00042 20.1 0.2 0.16 11.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 OAG13031.1 - 0.00049 20.1 0.1 2.8 7.9 0.0 3.4 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit AAA_24 PF13479.6 OAG13031.1 - 0.00051 19.8 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 OAG13031.1 - 0.00058 20.1 0.2 0.37 11.0 0.0 2.9 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase DUF99 PF01949.16 OAG13031.1 - 0.0012 18.3 2.8 0.12 11.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function DUF99 SRP54 PF00448.22 OAG13031.1 - 0.0013 18.3 2.4 0.073 12.7 0.0 2.9 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OAG13031.1 - 0.0015 18.7 1.1 3.5 7.8 0.0 3.4 4 0 0 4 4 2 2 AAA domain TrwB_AAD_bind PF10412.9 OAG13031.1 - 0.0017 17.3 0.0 1.8 7.4 0.0 2.6 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 OAG13031.1 - 0.0018 18.8 2.1 3.4 8.2 0.0 3.4 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.12 OAG13031.1 - 0.0026 17.1 0.0 0.97 8.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 OAG13031.1 - 0.0037 17.6 0.1 0.62 10.4 0.2 3.0 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 OAG13031.1 - 0.0043 16.5 0.1 0.043 13.3 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 OAG13031.1 - 0.0054 15.9 0.5 0.32 10.1 0.1 3.3 2 2 0 2 2 2 1 Protein of unknown function (DUF815) PduV-EutP PF10662.9 OAG13031.1 - 0.0066 16.2 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 OAG13031.1 - 0.0078 16.2 0.4 4.7 7.2 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 OAG13031.1 - 0.014 14.4 0.0 0.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DUF87 PF01935.17 OAG13031.1 - 0.021 14.9 2.0 27 4.7 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 OAG13031.1 - 0.022 14.7 0.7 11 5.8 0.0 3.2 3 1 1 4 4 3 0 RsgA GTPase AAA_17 PF13207.6 OAG13031.1 - 0.042 14.3 4.3 3.1 8.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 OAG13031.1 - 0.049 13.2 0.4 2.3 7.8 0.1 3.0 2 1 1 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 OAG13031.1 - 0.06 13.1 0.7 1.2 8.9 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 OAG13031.1 - 0.067 13.1 0.0 1.9 8.4 0.0 2.9 2 0 0 2 2 2 0 NTPase COPR5 PF15340.6 OAG13031.1 - 0.23 12.1 0.8 0.97 10.1 0.8 1.9 2 0 0 2 2 1 0 Cooperator of PRMT5 family HAUS2 PF15003.6 OAG13031.1 - 0.92 9.2 6.8 3.8 7.2 0.9 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 GAS PF13851.6 OAG13031.1 - 2.4 7.5 15.8 6.3 6.1 15.8 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 OAG13031.1 - 4.5 6.6 7.3 7.9 5.7 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TIP49 PF06068.13 OAG13031.1 - 7.1 5.7 8.7 1.1 8.4 0.3 3.5 3 2 1 5 5 5 0 TIP49 P-loop domain DUF4061 PF13270.6 OAG13031.1 - 8.8 6.7 13.2 2.3 8.6 1.7 3.6 3 1 1 4 4 3 0 Domain of unknown function (DUF4061) EF1_GNE PF00736.19 OAG13032.1 - 3.9e-30 103.9 3.4 3.9e-30 103.9 3.4 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OAG13032.1 - 1.7e-12 47.6 6.6 1.7e-12 47.6 6.6 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 OAG13032.1 - 0.071 13.3 0.2 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Arginase PF00491.21 OAG13034.1 - 1.1e-93 313.8 0.0 1.4e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAG13034.1 - 0.0091 16.2 0.2 0.018 15.3 0.2 1.4 1 0 0 1 1 1 1 UPF0489 domain Fapy_DNA_glyco PF01149.24 OAG13035.1 - 3.2e-29 101.9 0.0 6.1e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 OAG13035.1 - 6.1e-20 71.0 0.0 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 OAG13035.1 - 0.0072 15.1 0.1 0.019 13.7 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NARP1 PF12569.8 OAG13036.1 - 4.6e-198 659.3 27.5 5.7e-198 659.0 22.4 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 OAG13036.1 - 2.1e-16 60.3 26.5 2.6e-05 24.8 0.3 8.5 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG13036.1 - 2.6e-13 50.2 33.1 0.0061 17.0 1.1 7.4 7 1 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG13036.1 - 2.8e-13 49.5 21.1 0.022 15.5 0.1 9.3 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG13036.1 - 1.1e-12 47.0 39.2 4.2e-05 23.3 0.2 10.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG13036.1 - 3.3e-11 42.5 27.4 4.6e-05 23.1 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG13036.1 - 8e-10 38.8 20.6 0.00013 22.1 0.7 6.0 3 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAG13036.1 - 6.3e-08 32.7 16.3 0.0051 16.9 0.1 6.2 5 3 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG13036.1 - 1.4e-06 28.1 29.3 0.017 15.3 0.1 9.0 10 0 0 10 10 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAG13036.1 - 1.8e-06 27.6 14.9 0.18 11.9 0.1 8.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG13036.1 - 1.8e-06 27.5 23.2 0.00024 20.7 0.1 7.1 8 1 1 9 9 9 3 TPR repeat TPR_17 PF13431.6 OAG13036.1 - 2.1e-05 24.6 19.4 0.0099 16.2 0.0 8.1 8 0 0 8 8 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG13036.1 - 0.0021 18.1 0.1 0.0021 18.1 0.1 6.9 8 0 0 8 8 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 OAG13036.1 - 0.01 16.4 2.8 5 8.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG13036.1 - 0.017 15.4 25.9 1.1 9.6 0.1 7.0 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAG13036.1 - 0.018 15.0 8.2 2.5 8.2 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3287 PF11690.8 OAG13036.1 - 0.021 14.5 0.0 0.43 10.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Alkyl_sulf_dimr PF14863.6 OAG13036.1 - 0.11 12.9 12.0 3.4 8.1 0.1 4.6 4 1 1 5 5 5 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 OAG13036.1 - 0.11 13.1 20.3 2.5 8.9 0.1 8.6 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG13036.1 - 0.4 10.6 13.2 1.8 8.5 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DAO PF01266.24 OAG13037.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 OAG13037.1 - 0.0031 17.7 0.0 0.0034 17.6 0.0 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAG13037.1 - 0.016 15.1 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG13037.1 - 0.031 13.5 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 OAG13037.1 - 0.051 12.9 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 OAG13037.1 - 0.2 11.3 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UQ_con PF00179.26 OAG13039.1 - 2.2e-32 111.6 0.0 3.9e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG13039.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B CBM49 PF09478.10 OAG13039.1 - 0.058 13.7 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Nup160 PF11715.8 OAG13040.1 - 8.4e-114 381.1 0.3 1.1e-113 380.8 0.3 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Linocin_M18 PF04454.12 OAG13042.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Encapsulating protein for peroxidase RabGAP-TBC PF00566.18 OAG13044.1 - 9.1e-48 162.7 0.4 1.5e-47 162.1 0.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SprT-like PF10263.9 OAG13045.1 - 5.8e-21 74.5 0.1 1.3e-20 73.3 0.0 1.6 2 0 0 2 2 2 1 SprT-like family TryThrA_C PF12319.8 OAG13045.1 - 0.033 13.7 2.7 0.047 13.2 2.7 1.1 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Ribosomal_L23 PF00276.20 OAG13046.1 - 1.8e-09 37.8 0.0 3.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 tRNA-synt_2b PF00587.25 OAG13048.1 - 2.8e-34 118.7 0.0 3.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG13048.1 - 3.4e-09 36.7 0.2 8.9e-09 35.4 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_L10 PF00466.20 OAG13049.1 - 0.0015 18.7 0.0 0.063 13.4 0.1 2.4 2 1 0 2 2 2 2 Ribosomal protein L10 HIT PF01230.23 OAG13050.1 - 7.6e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain Cyclin_N PF00134.23 OAG13051.1 - 5e-45 152.3 0.2 1.4e-44 150.9 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG13051.1 - 8e-33 113.1 0.0 1.6e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain SapB_2 PF03489.17 OAG13051.1 - 0.14 12.3 0.8 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 2 Ribosomal_L2_C PF03947.18 OAG13052.1 - 1.1e-47 161.3 2.6 2.7e-47 160.1 2.4 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAG13052.1 - 1.7e-24 85.6 1.6 4e-24 84.4 1.6 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.18 OAG13053.1 - 6.7e-20 71.2 0.9 1.1e-19 70.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13053.1 - 2.7e-09 37.0 9.9 5.4e-09 36.0 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3336 PF11815.8 OAG13055.1 - 1e-33 116.0 0.1 2.3e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG13055.1 - 1.1e-14 55.1 0.6 2e-14 54.2 0.2 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Glyco_hydro_35 PF01301.19 OAG13056.1 - 2.7e-93 313.1 0.4 4.6e-93 312.3 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 OAG13056.1 - 6.4e-58 195.5 6.8 1.1e-57 194.7 6.8 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 OAG13056.1 - 1.2e-56 190.2 9.1 1.1e-32 112.9 0.1 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 OAG13056.1 - 2.8e-22 78.0 0.1 1.2e-21 76.0 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Fungal_trans PF04082.18 OAG13057.1 - 2.6e-14 52.9 0.2 5.9e-14 51.7 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13057.1 - 0.74 10.0 15.0 0.13 12.4 10.1 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 OAG13058.1 - 8.1e-07 28.7 0.0 0.021 14.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG13058.1 - 1.8e-06 28.0 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HTH_42 PF06224.12 OAG13058.1 - 0.0091 15.6 0.5 0.049 13.2 0.3 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain 3Beta_HSD PF01073.19 OAG13058.1 - 0.024 13.7 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG13058.1 - 0.025 15.0 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.25 OAG13059.1 - 2.6e-60 204.0 0.2 6.9e-60 202.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13059.1 - 1.3e-35 122.9 0.0 2.6e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 OAG13059.1 - 1.2e-27 95.8 12.8 4.6e-16 58.7 5.8 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 OAG13059.1 - 4.5e-21 74.5 31.0 1.5e-12 47.2 9.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 OAG13059.1 - 3.9e-14 53.1 1.6 1.8e-13 51.0 1.6 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAG13059.1 - 0.037 13.3 0.0 0.082 12.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OAG13059.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Uds1 PF15456.6 OAG13059.1 - 0.16 12.1 3.4 0.18 11.9 0.5 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DUF3008 PF11450.8 OAG13059.1 - 1.6 9.0 8.0 4 7.7 8.0 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) PI-PLC-X PF00388.19 OAG13060.1 - 1.1e-08 34.8 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Hox9_act PF04617.13 OAG13060.1 - 0.04 14.7 0.6 0.076 13.8 0.6 1.4 1 0 0 1 1 1 0 Hox9 activation region SIR2 PF02146.17 OAG13061.1 - 1.3e-28 100.2 0.0 4.2e-28 98.5 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 OAG13061.1 - 0.0016 18.5 1.2 0.0054 16.8 1.2 1.9 1 0 0 1 1 1 1 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 OAG13061.1 - 1.7 8.7 4.4 10 6.2 0.6 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF35_N PF12172.8 OAG13061.1 - 8.9 6.3 6.7 12 5.9 1.6 2.9 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Med16 PF11635.8 OAG13062.1 - 7.5e-154 513.5 0.4 8.6e-154 513.4 0.4 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 OAG13062.1 - 0.091 13.1 0.0 3.3 8.1 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TRP_N PF14558.6 OAG13062.1 - 0.092 13.1 0.2 0.21 11.9 0.2 1.5 1 0 0 1 1 1 0 ML-like domain POPLD PF08170.12 OAG13062.1 - 0.13 12.7 0.1 9.4 6.7 0.1 2.5 2 0 0 2 2 2 0 POPLD (NUC188) domain YchF-GTPase_C PF06071.13 OAG13063.1 - 5e-33 113.1 0.1 1.2e-32 111.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OAG13063.1 - 8.9e-17 61.2 0.0 3.8e-16 59.2 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG13063.1 - 0.00042 19.9 0.0 0.00085 18.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 OAG13063.1 - 0.0007 19.6 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 OAG13063.1 - 0.059 13.4 0.1 1.4 9.0 0.0 2.5 2 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.6 OAG13063.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAG13063.1 - 0.34 11.4 3.3 9.3 6.7 3.1 2.4 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.14 OAG13064.1 - 2.8e-33 114.9 0.0 3.4e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 OAG13064.1 - 0.00018 21.8 0.1 0.00038 20.7 0.0 1.5 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DUF778 PF05608.12 OAG13064.1 - 0.14 12.5 0.7 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF778) Ribosomal_S11 PF00411.19 OAG13065.1 - 8.6e-10 39.0 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 OAG13066.1 - 2.6e-34 118.4 0.0 6.4e-34 117.2 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain Moricin PF06451.11 OAG13066.1 - 0.033 14.0 1.7 2.6 7.9 0.6 2.5 2 0 0 2 2 2 0 Moricin Menin PF05053.13 OAG13066.1 - 6.3 5.0 6.6 8.5 4.6 6.6 1.1 1 0 0 1 1 1 0 Menin 4HBT PF03061.22 OAG13067.1 - 2.2e-11 44.0 0.0 4.9e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Acetyltransf_1 PF00583.25 OAG13069.1 - 7.6e-15 55.2 0.0 9.9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG13069.1 - 2.1e-09 37.4 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG13069.1 - 8.8e-09 35.7 0.1 1.4e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG13069.1 - 0.0021 18.2 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG13069.1 - 0.012 15.6 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 OAG13069.1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAG13069.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 OAG13070.1 - 0.013 15.7 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 OAG13071.1 - 0.00065 19.9 0.0 0.024 14.8 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG13071.1 - 0.0095 16.2 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans_2 PF11951.8 OAG13072.1 - 2.4e-09 36.5 1.7 4.3e-09 35.7 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RIC1 PF07064.13 OAG13073.1 - 7.8e-94 313.8 0.1 1.1e-93 313.3 0.1 1.2 1 0 0 1 1 1 1 RIC1 Git3 PF11710.8 OAG13074.1 - 2.2e-21 76.6 13.3 4e-21 75.7 13.3 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OAG13074.1 - 3e-10 39.9 5.0 3.8e-10 39.5 5.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 OAG13074.1 - 3.3e-06 27.1 0.3 3.3e-06 27.1 0.3 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term PXA PF02194.15 OAG13076.1 - 1.5e-49 168.5 1.2 1.6e-48 165.1 0.1 3.0 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 OAG13076.1 - 3.6e-26 91.9 0.0 1.2e-25 90.3 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 OAG13076.1 - 3.9e-20 71.9 1.0 6.3e-20 71.2 0.1 1.9 2 0 0 2 2 2 1 PX domain RGS PF00615.19 OAG13076.1 - 5.1e-09 36.4 0.0 1.5e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF5555 PF17710.1 OAG13076.1 - 0.089 12.3 2.4 2 7.9 0.5 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5555) HlyD_2 PF12700.7 OAG13076.1 - 0.13 11.0 0.4 0.23 10.2 0.4 1.3 1 0 0 1 1 1 0 HlyD family secretion protein RRP36 PF06102.12 OAG13076.1 - 9.6 6.1 9.8 1.2 9.1 3.3 2.3 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 F-box-like_2 PF13013.6 OAG13077.1 - 0.0042 17.0 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 F-box-like domain T5orf172 PF10544.9 OAG13078.1 - 1e-14 54.9 0.0 4.3e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 OAG13078.1 - 1.7e-09 38.2 0.1 4.2e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 NAD_binding_10 PF13460.6 OAG13079.1 - 4e-11 43.1 0.2 6.6e-11 42.4 0.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG13079.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family UDPGT PF00201.18 OAG13079.1 - 0.038 12.8 0.1 0.043 12.6 0.1 1.0 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase F420_oxidored PF03807.17 OAG13079.1 - 0.048 14.2 0.1 0.1 13.2 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OAG13079.1 - 0.071 12.6 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELYS PF13934.6 OAG13079.1 - 0.16 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex assembly Pectate_lyase PF03211.13 OAG13080.1 - 1.1e-84 283.0 6.9 1.3e-84 282.8 6.9 1.0 1 0 0 1 1 1 1 Pectate lyase GMC_oxred_N PF00732.19 OAG13081.1 - 2e-69 234.3 0.0 4.7e-69 233.0 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG13081.1 - 9.6e-31 107.2 0.0 1.7e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG13081.1 - 9e-08 31.6 1.7 0.0014 17.8 0.2 3.5 4 0 0 4 4 4 2 FAD binding domain Lycopene_cycl PF05834.12 OAG13081.1 - 2.3e-05 23.6 0.1 4.4e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAG13081.1 - 4.2e-05 23.3 0.8 0.0064 16.1 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG13081.1 - 0.00012 21.4 0.1 0.0034 16.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG13081.1 - 0.00049 20.3 0.2 0.0016 18.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG13081.1 - 0.00086 18.6 0.1 0.0024 17.2 0.1 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG13081.1 - 0.0033 16.7 0.6 0.61 9.3 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG13081.1 - 0.004 17.7 0.2 1.1 9.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG13081.1 - 0.014 14.1 0.1 0.032 12.9 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein AMP-binding PF00501.28 OAG13083.1 - 8.2e-75 252.0 0.0 1.5e-74 251.1 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAG13083.1 - 3e-62 210.1 0.0 6.4e-62 209.0 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 OAG13083.1 - 7.7e-49 165.8 1.0 1.6e-48 164.8 1.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG13083.1 - 9.7e-39 133.3 1.5 2.2e-38 132.1 0.4 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG13083.1 - 1.7e-16 60.7 0.8 1.8e-13 50.8 0.4 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAG13083.1 - 3e-14 53.1 0.1 4.9e-09 36.0 0.0 3.9 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG13083.1 - 5.4e-13 49.1 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAG13083.1 - 2.7e-07 29.9 0.0 0.001 18.1 0.0 3.2 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG13083.1 - 3.8e-05 23.0 0.6 0.43 9.7 0.1 3.2 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG13083.1 - 8e-05 22.6 0.3 0.0011 18.9 0.5 2.8 3 1 0 3 3 3 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG13083.1 - 0.00012 21.3 0.5 0.0071 15.5 0.0 3.0 4 0 0 4 4 4 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAG13083.1 - 0.0057 16.1 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase ApbA PF02558.16 OAG13083.1 - 0.049 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 OAG13084.1 - 1.2e-26 93.5 31.1 1.7e-25 89.7 31.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily SLATT_1 PF18181.1 OAG13086.1 - 0.028 14.4 1.4 0.075 13.0 0.5 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 FAD_binding_3 PF01494.19 OAG13087.1 - 6e-16 58.6 0.0 3.9e-12 46.1 0.0 2.2 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG13087.1 - 9.3e-08 32.2 0.6 3.9e-07 30.2 0.6 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG13087.1 - 2.9e-06 27.1 1.1 7.7e-06 25.7 0.9 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG13087.1 - 0.00011 21.1 0.1 0.00019 20.3 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG13087.1 - 0.00052 19.2 0.3 0.00087 18.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OAG13087.1 - 0.00056 19.9 0.2 0.11 12.5 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG13087.1 - 0.00092 18.5 0.1 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAG13087.1 - 0.0018 17.5 0.1 0.0037 16.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG13087.1 - 0.0034 16.5 0.0 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 OAG13087.1 - 0.0037 17.8 0.3 0.0083 16.7 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG13087.1 - 0.011 14.6 0.8 0.023 13.6 0.1 1.8 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 OAG13087.1 - 0.03 13.4 0.3 0.047 12.8 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 OAG13087.1 - 0.045 13.1 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAG13087.1 - 0.087 12.1 1.0 0.16 11.2 1.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.23 OAG13090.1 - 7.2e-22 77.6 1.6 1.4e-21 76.7 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 OAG13091.1 - 1.6e-49 168.9 0.0 2.7e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG13091.1 - 4.3e-37 127.8 0.0 8.3e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAG13091.1 - 5.4e-07 29.5 0.7 1.5e-06 28.0 0.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG13091.1 - 2.3e-06 27.0 2.8 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 OAG13091.1 - 0.00017 20.9 1.9 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG13091.1 - 0.011 15.0 0.1 0.026 13.8 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG13091.1 - 0.086 13.1 3.6 0.32 11.3 3.6 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG13091.1 - 0.12 11.3 0.3 0.18 10.6 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 OAG13091.1 - 0.16 11.0 0.3 0.29 10.1 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Nitroreductase PF00881.24 OAG13093.1 - 1.6e-09 38.0 0.0 2.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Cas_csx3 PF09620.10 OAG13093.1 - 0.0057 16.5 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_csx3) DUF3983 PF13137.6 OAG13093.1 - 0.21 11.4 0.3 0.43 10.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) HET PF06985.11 OAG13094.1 - 6.2e-31 107.7 0.1 3.3e-30 105.4 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GST_N_3 PF13417.6 OAG13095.1 - 3.9e-20 72.0 0.0 7.8e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG13095.1 - 9.6e-17 61.1 0.1 3.7e-16 59.2 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG13095.1 - 3.5e-08 33.7 0.0 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG13095.1 - 1.5e-06 28.1 0.2 3.5e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG13095.1 - 0.00026 21.5 0.0 0.0005 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 OAG13096.1 - 1e-08 35.1 10.4 1.7e-08 34.4 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC85 PF10226.9 OAG13097.1 - 0.24 11.1 1.7 0.36 10.5 1.7 1.2 1 0 0 1 1 1 0 CCDC85 family Alpha-L-AF_C PF06964.12 OAG13098.1 - 2.2e-22 80.0 0.0 3.9e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 OAG13098.1 - 0.0053 17.0 4.9 0.0097 16.2 2.5 2.6 2 1 0 2 2 2 1 Carbohydrate binding domain Peptidase_M75 PF09375.10 OAG13098.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Imelysin PAF-AH_p_II PF03403.13 OAG13099.1 - 4.4e-15 55.1 0.0 1.1e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAG13099.1 - 3e-05 23.4 0.5 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG13099.1 - 0.0002 22.0 4.4 0.0005 20.8 4.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG13099.1 - 0.00041 20.1 0.2 0.37 10.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 OAG13099.1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 OAG13099.1 - 0.058 12.3 0.0 0.13 11.2 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme HAD PF12710.7 OAG13100.1 - 2e-20 74.0 0.0 2.8e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAG13100.1 - 0.0014 18.1 0.0 0.019 14.4 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 OAG13100.1 - 0.0091 15.5 0.0 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 OAG13100.1 - 0.051 13.9 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 OAG13102.1 - 9e-42 143.2 52.4 4.6e-40 137.6 52.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG13102.1 - 1.2e-12 47.1 24.9 1.8e-12 46.5 24.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG13102.1 - 1.3e-08 34.2 3.9 1.3e-08 34.2 3.9 3.5 3 0 0 3 3 3 3 Sugar (and other) transporter SBP_bac_3 PF00497.20 OAG13103.1 - 1.9e-29 102.7 0.0 2.3e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SNAD4 PF18750.1 OAG13104.1 - 0.026 14.6 0.5 0.03 14.4 0.5 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Flavi_glycop_C PF02832.16 OAG13104.1 - 0.033 14.3 0.1 0.041 14.0 0.1 1.1 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain 14-3-3 PF00244.20 OAG13106.1 - 1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 14-3-3 protein HAT PF02184.16 OAG13107.1 - 1.9e-25 88.5 71.7 4.2e-14 52.2 2.6 14.1 15 0 0 15 15 15 8 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 OAG13107.1 - 1.4e-23 81.6 29.0 0.0029 18.3 0.3 11.7 7 3 6 13 13 12 8 Tetratricopeptide repeat TPR_19 PF14559.6 OAG13107.1 - 1e-18 67.6 1.8 5e-05 23.7 0.0 7.1 7 1 0 8 8 7 3 Tetratricopeptide repeat Suf PF05843.14 OAG13107.1 - 9.4e-14 52.1 21.1 0.00052 20.1 2.6 6.4 2 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_2 PF07719.17 OAG13107.1 - 2.1e-09 36.8 6.8 1.1 9.5 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG13107.1 - 5e-06 26.3 1.4 37 4.9 0.0 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG13107.1 - 2.7e-05 24.3 6.8 0.11 12.9 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 OAG13107.1 - 0.0011 18.2 19.7 0.2 10.8 1.6 6.1 2 2 2 4 4 4 4 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 OAG13107.1 - 0.0019 18.7 14.7 10 7.0 0.0 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 OAG13107.1 - 0.012 15.7 18.7 0.04 14.0 2.3 6.4 5 2 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.6 OAG13107.1 - 0.12 12.6 21.3 6.7 7.1 0.0 8.4 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG13107.1 - 1.8 9.3 27.8 7.2 7.3 0.0 8.3 11 0 0 11 11 11 0 Tetratricopeptide repeat Fic PF02661.18 OAG13107.1 - 3.2 8.7 4.6 8.1 7.4 0.0 3.5 4 0 0 4 4 4 0 Fic/DOC family c-SKI_SMAD_bind PF08782.10 OAG13107.1 - 7.2 6.9 6.9 1.6 9.0 0.2 3.5 4 0 0 4 4 4 0 c-SKI Smad4 binding domain Nop PF01798.18 OAG13108.1 - 1.3e-68 230.9 0.0 1.8e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OAG13108.1 - 2.3e-44 151.2 1.1 2.3e-44 151.2 1.1 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain JAB PF01398.21 OAG13109.1 - 3.2e-08 33.6 0.0 3.8e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease COesterase PF00135.28 OAG13110.1 - 3.4e-83 280.3 0.0 4.8e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG13110.1 - 5.9e-08 32.8 0.3 5.3e-06 26.4 0.1 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG13110.1 - 0.32 9.8 0.0 0.63 8.8 0.0 1.3 1 1 0 1 1 1 0 Steryl acetyl hydrolase ATP_bind_3 PF01171.20 OAG13111.1 - 1.2e-37 129.5 0.0 2.5e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 OAG13111.1 - 0.00027 20.7 0.8 0.0005 19.8 0.0 1.8 2 0 0 2 2 2 1 Asparagine synthase Cpn10 PF00166.21 OAG13112.1 - 4.9e-27 93.8 0.0 5.5e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit WD40 PF00400.32 OAG13113.1 - 1.1e-51 171.6 10.1 6.7e-11 42.6 0.2 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG13113.1 - 2.8e-16 59.6 0.4 0.005 17.1 0.0 4.7 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 OAG13113.1 - 5.7e-10 39.4 0.1 1.6e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 OAG13113.1 - 7.5e-10 38.3 3.0 0.29 10.1 0.0 5.0 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Helo_like_N PF17111.5 OAG13113.1 - 4e-09 36.1 0.4 8.3e-09 35.1 0.4 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins eIF2A PF08662.11 OAG13113.1 - 8.7e-08 32.3 0.0 0.0076 16.1 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAG13113.1 - 1.8e-07 30.2 4.2 0.63 8.6 0.1 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.12 OAG13113.1 - 5.2e-07 29.4 0.0 7.1 6.7 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 OAG13113.1 - 5.5e-06 26.9 0.1 5.5e-06 26.9 0.1 2.6 4 0 0 4 4 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG13113.1 - 6.2e-05 23.3 1.0 0.00074 19.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain IKI3 PF04762.12 OAG13113.1 - 8.3e-05 20.8 0.1 0.1 10.6 0.0 3.3 1 1 3 4 4 4 3 IKI3 family Defensin_RK-1 PF17860.1 OAG13113.1 - 0.00019 21.8 0.4 49 4.5 0.0 4.3 4 0 0 4 4 4 0 RK-1-like defensin DUF4189 PF13827.6 OAG13113.1 - 0.0016 18.9 4.2 1.7 9.2 0.5 3.4 1 1 2 3 3 3 2 Domain of unknown function (DUF4189) Proteasome_A_N PF10584.9 OAG13113.1 - 0.0037 16.9 0.0 75 3.1 0.0 4.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature SesA PF17107.5 OAG13113.1 - 0.0043 17.2 0.5 0.011 16.0 0.5 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA PF00004.29 OAG13113.1 - 0.0075 16.7 0.1 0.036 14.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Utp13 PF08625.11 OAG13113.1 - 0.013 15.4 1.4 0.021 14.8 0.1 2.0 2 0 0 2 2 1 0 Utp13 specific WD40 associated domain AAA_30 PF13604.6 OAG13113.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG13113.1 - 0.037 14.6 0.2 0.54 10.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 OAG13113.1 - 0.046 13.6 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 OAG13113.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain SKA1 PF07160.12 OAG13113.1 - 0.054 13.4 0.9 0.1 12.4 0.9 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TruB_C PF09142.11 OAG13113.1 - 0.066 13.0 0.9 42 4.0 0.0 3.8 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal RNA_helicase PF00910.22 OAG13113.1 - 0.068 13.6 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF2730 PF10805.8 OAG13113.1 - 0.073 13.2 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Nbas_N PF15492.6 OAG13113.1 - 0.077 12.3 1.7 16 4.7 0.0 3.4 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal OmpH PF03938.14 OAG13113.1 - 0.098 13.0 2.4 0.19 12.0 2.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Noelin-1 PF12308.8 OAG13113.1 - 0.14 12.1 2.2 2.2 8.3 0.4 3.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein AAA_33 PF13671.6 OAG13113.1 - 0.15 12.3 0.0 0.52 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain Spectrin PF00435.21 OAG13113.1 - 0.16 12.4 3.2 0.42 11.1 3.2 1.6 1 0 0 1 1 1 0 Spectrin repeat WD40_like PF17005.5 OAG13113.1 - 0.2 10.9 0.0 26 4.0 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain DUF3450 PF11932.8 OAG13113.1 - 0.26 10.6 3.1 0.47 9.7 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 OAG13113.1 - 0.32 11.5 3.6 0.47 11.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 OAG13113.1 - 0.56 10.9 5.3 1.8 9.3 5.3 1.9 1 0 0 1 1 1 0 SlyX KAP_NTPase PF07693.14 OAG13113.1 - 0.7 9.1 5.0 0.12 11.6 0.5 2.0 2 1 0 2 2 2 0 KAP family P-loop domain TFIIIC_delta PF12657.7 OAG13113.1 - 1 9.3 7.8 48 3.8 0.0 4.7 5 0 0 5 5 5 0 Transcription factor IIIC subunit delta N-term Bradykinin PF06753.12 OAG13115.1 - 0.49 10.2 2.6 0.69 9.7 0.0 2.6 3 0 0 3 3 3 0 Bradykinin Mito_carr PF00153.27 OAG13116.1 - 2.2e-41 139.7 11.7 6.3e-16 58.1 3.5 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein TrbI PF03743.14 OAG13116.1 - 0.22 11.3 3.3 0.78 9.5 3.3 1.8 1 1 0 1 1 1 0 Bacterial conjugation TrbI-like protein YtxH PF12732.7 OAG13116.1 - 2.9 8.5 5.9 0.93 10.1 1.0 2.7 3 0 0 3 3 3 0 YtxH-like protein DUF3328 PF11807.8 OAG13117.1 - 3.3e-32 112.0 1.4 4e-32 111.8 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pro-kuma_activ PF09286.11 OAG13118.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain AF-4 PF05110.13 OAG13118.1 - 0.18 9.9 13.7 0.21 9.6 13.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ank_4 PF13637.6 OAG13119.1 - 5.6e-11 42.8 4.3 0.0026 18.3 0.4 5.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG13119.1 - 8.9e-11 42.2 2.6 0.0018 18.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG13119.1 - 3.8e-09 36.0 2.5 0.16 12.6 0.0 6.4 7 1 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 OAG13119.1 - 2e-07 31.1 1.9 0.009 16.4 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAG13119.1 - 4.4e-07 30.0 1.9 0.00031 21.0 0.1 4.1 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Het-C PF07217.11 OAG13120.1 - 8.9e-273 905.9 0.0 1.1e-272 905.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Condensin2nSMC PF12422.8 OAG13120.1 - 0.14 12.4 0.1 4.4 7.5 0.0 2.3 1 1 1 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit adh_short_C2 PF13561.6 OAG13121.1 - 1.8e-53 181.5 1.6 2.2e-53 181.2 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG13121.1 - 2e-45 154.6 0.5 2.5e-45 154.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG13121.1 - 3.6e-08 33.5 0.5 7.9e-08 32.4 0.5 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG13121.1 - 6.2e-05 22.6 0.1 0.00011 21.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family tRNA_int_end_N2 PF12928.7 OAG13122.1 - 2.4e-24 85.3 0.0 4.5e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term IPK PF03770.16 OAG13124.1 - 9.3e-56 188.8 0.0 1.6e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase BRF1 PF07741.13 OAG13124.1 - 3.9 7.9 5.6 7.2 7.0 1.6 3.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain LRR_4 PF12799.7 OAG13126.1 - 6.8e-21 74.0 36.0 3.2e-05 24.2 1.8 8.7 6 2 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG13126.1 - 1.1e-16 60.3 35.7 3e-07 30.1 1.6 6.3 4 2 1 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 OAG13126.1 - 6.7e-13 48.5 12.7 0.0015 18.0 0.3 4.5 2 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 OAG13126.1 - 0.04 14.0 27.8 1.1 9.5 0.8 8.0 9 0 0 9 9 9 0 Leucine Rich repeat TEX19 PF15553.6 OAG13126.1 - 0.12 12.3 0.1 0.38 10.7 0.1 1.8 1 0 0 1 1 1 0 Testis-expressed protein 19 Herpes_BLRF2 PF05812.12 OAG13126.1 - 0.19 11.8 2.0 19 5.4 0.1 2.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein LRR_1 PF00560.33 OAG13126.1 - 3 8.7 25.8 2.8 8.8 0.3 8.5 7 3 1 8 8 8 0 Leucine Rich Repeat UNC45-central PF11701.8 OAG13127.1 - 4.7e-43 146.8 5.2 9.1e-43 145.9 3.3 2.4 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central TPR_14 PF13428.6 OAG13127.1 - 0.00073 20.1 2.0 0.007 17.1 0.2 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT PF02985.22 OAG13127.1 - 0.034 14.4 2.2 17 6.0 0.0 4.5 3 0 0 3 3 3 0 HEAT repeat TPR_2 PF07719.17 OAG13127.1 - 0.046 13.9 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Tom5 PF10642.9 OAG13127.1 - 0.047 13.7 0.4 0.16 12.0 0.4 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase TetR_C_28 PF17937.1 OAG13127.1 - 0.11 13.0 4.8 0.14 12.7 0.0 3.4 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Adaptin_N PF01602.20 OAG13127.1 - 0.51 8.8 3.2 0.48 8.9 0.4 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Arm PF00514.23 OAG13127.1 - 1.1 9.4 12.9 34 4.7 0.7 6.2 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat tRNA-synt_2 PF00152.20 OAG13128.1 - 1.4e-75 254.3 1.7 2e-75 253.8 1.7 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 OAG13128.1 - 1.6e-05 24.5 0.1 0.027 13.9 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 OAG13128.1 - 7.6e-05 22.6 0.0 0.0002 21.2 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF1604 PF07713.13 OAG13130.1 - 1.4e-40 137.0 2.7 4.1e-40 135.5 2.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OAG13130.1 - 0.0091 15.9 0.2 0.0091 15.9 0.2 2.3 3 0 0 3 3 3 1 G-patch domain Pkinase PF00069.25 OAG13131.1 - 1.2e-71 241.2 0.0 2.1e-71 240.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG13131.1 - 6.2e-41 140.4 0.0 1.7e-40 138.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OAG13131.1 - 2e-17 62.7 0.2 4.2e-17 61.7 0.2 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OAG13131.1 - 8.2e-06 25.3 0.0 7.7e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAG13131.1 - 1.9e-05 24.2 0.1 3.3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG13131.1 - 6.3e-05 22.1 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG13131.1 - 0.00085 19.3 0.1 0.0084 16.0 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 OAG13131.1 - 0.054 13.1 0.1 0.092 12.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 OAG13131.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 OAG13131.1 - 0.19 11.3 2.0 0.18 11.4 0.2 1.8 2 1 0 2 2 2 0 RIO1 family ABC1 PF03109.16 OAG13131.1 - 0.19 11.9 0.1 0.43 10.7 0.1 1.5 1 0 0 1 1 1 0 ABC1 family Rcd1 PF04078.13 OAG13132.1 - 4.2e-127 422.8 2.8 5e-127 422.6 2.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.18 OAG13132.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.0 2 1 0 2 2 2 0 ATP synthase delta (OSCP) subunit Ribosomal_L1 PF00687.21 OAG13133.1 - 3.6e-47 160.8 0.6 4.1e-47 160.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ndr PF03096.14 OAG13133.1 - 0.03 13.0 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Cid2 PF09774.9 OAG13134.1 - 3.8e-53 180.2 0.1 4.4e-53 180.0 0.1 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DNA_ligase_A_M PF01068.21 OAG13135.1 - 1.6e-60 204.2 1.5 8.2e-48 162.7 0.4 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAG13135.1 - 6.2e-44 150.4 0.1 1.4e-43 149.2 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAG13135.1 - 6.4e-29 100.5 0.0 2.8e-28 98.4 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 OAG13135.1 - 4.4e-06 27.1 0.2 7.2e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 RNA ligase AT_hook PF02178.19 OAG13135.1 - 0.13 12.2 3.9 0.67 10.0 3.9 2.3 1 0 0 1 1 1 0 AT hook motif Nre_C PF04895.12 OAG13136.1 - 0.29 11.1 8.8 0.12 12.3 0.6 3.4 2 1 1 3 3 3 0 Archaeal Nre, C-terminal DUF948 PF06103.11 OAG13136.1 - 1.6 9.1 17.7 2.1 8.7 0.8 4.5 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) HMG_box PF00505.19 OAG13138.1 - 1.2e-08 35.2 0.4 3.6e-08 33.7 0.4 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box DUF4543 PF15076.6 OAG13138.1 - 0.13 12.4 1.4 0.24 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) Acetyltransf_1 PF00583.25 OAG13139.1 - 5.6e-07 29.8 0.0 7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG13139.1 - 0.00031 21.1 0.0 0.00045 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG13139.1 - 0.00055 19.9 0.0 0.00072 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG13139.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Sld5 PF05916.11 OAG13140.1 - 1.1e-13 51.5 0.0 1.7e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 OAG13140.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Sulfate_transp PF00916.20 OAG13141.1 - 1.8e-61 208.0 20.3 3.5e-61 207.1 20.3 1.4 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 OAG13141.1 - 7e-15 54.9 0.0 1.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OAG13141.1 - 1.8e-09 37.2 0.1 9.6e-09 34.9 0.2 2.1 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 OAG13141.1 - 2.5 8.5 24.2 0.39 11.1 0.9 3.9 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily EF-G-binding_N PF07299.11 OAG13142.1 - 0.044 14.3 0.1 0.081 13.5 0.1 1.4 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Ank_2 PF12796.7 OAG13143.1 - 1.9e-20 73.2 0.4 6.7e-12 45.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG13143.1 - 4.2e-11 42.9 0.5 2e-05 24.7 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG13143.1 - 7.4e-11 42.4 0.2 4.2e-06 27.2 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG13143.1 - 6.1e-10 38.5 0.1 0.0048 17.3 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OAG13143.1 - 1.2e-08 35.0 0.1 0.017 15.6 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat MOZART1 PF12554.8 OAG13143.1 - 0.14 11.9 0.2 2.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated PH_6 PF15406.6 OAG13145.1 - 7.7e-30 103.5 2.9 7.7e-30 103.5 2.9 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain UBD PF16455.5 OAG13145.1 - 5.8e-27 94.0 0.0 1.1e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain PH PF00169.29 OAG13145.1 - 0.0013 19.2 0.0 0.0064 17.0 0.0 2.3 2 1 0 2 2 2 1 PH domain Vac17 PF17321.2 OAG13145.1 - 0.0017 17.9 4.4 0.0031 17.0 4.4 1.3 1 0 0 1 1 1 1 Vacuole-related protein 17 ubiquitin PF00240.23 OAG13145.1 - 0.09 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Pinin_SDK_memA PF04696.13 OAG13145.1 - 1.1 9.3 12.1 0.19 11.8 5.4 2.9 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Citrate_synt PF00285.21 OAG13148.1 - 4.5e-122 407.6 0.0 5.7e-122 407.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain RGS-like PF09128.11 OAG13149.1 - 0.17 11.6 1.5 0.2 11.4 1.5 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF4452 PF14618.6 OAG13151.1 - 9.8e-72 240.3 14.4 1.2e-71 240.1 14.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Beta_helix PF13229.6 OAG13153.1 - 1.1e-07 31.9 7.8 2.3e-06 27.5 7.8 2.5 1 1 0 1 1 1 1 Right handed beta helix region Cyclin_N PF00134.23 OAG13154.1 - 2.8e-14 52.9 0.8 7.4e-11 41.9 0.2 2.6 3 0 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OAG13154.1 - 0.023 15.1 0.7 0.077 13.4 0.2 2.1 2 0 0 2 2 2 0 Cyclin C-terminal domain TFIIB PF00382.19 OAG13154.1 - 0.039 14.0 0.5 0.12 12.4 0.5 1.9 1 1 0 1 1 1 0 Transcription factor TFIIB repeat Mito_carr PF00153.27 OAG13155.1 - 1.1e-64 214.4 7.5 9e-22 76.8 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 OAG13155.1 - 9.1e-24 81.2 1.0 1.3e-05 24.4 0.4 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAG13155.1 - 8.5e-22 77.4 0.5 8e-10 39.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAG13155.1 - 3.3e-21 73.8 3.0 9.5e-06 24.9 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OAG13155.1 - 3.7e-18 63.8 3.3 1.1e-05 24.9 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OAG13155.1 - 2.8e-15 55.9 0.2 1.5e-08 34.4 0.0 3.0 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAG13155.1 - 3e-08 34.0 0.0 0.00093 19.5 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OAG13155.1 - 0.0075 16.4 1.3 0.13 12.5 0.1 2.7 3 0 0 3 3 3 1 Dockerin type I domain SNARE PF05739.19 OAG13156.1 - 2e-06 27.7 0.6 3.4e-06 27.0 0.6 1.3 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 OAG13156.1 - 0.0065 16.2 0.2 0.036 13.8 0.2 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 HemX PF04375.14 OAG13156.1 - 0.048 12.9 2.0 0.74 9.0 0.2 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Synaptobrevin PF00957.21 OAG13156.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Synaptobrevin ABC_tran_CTD PF16326.5 OAG13156.1 - 0.12 12.7 0.6 1.4 9.3 0.2 2.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 OAG13156.1 - 0.2 11.7 1.7 0.33 11.0 0.4 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 OAG13156.1 - 0.48 9.7 0.0 0.48 9.7 0.0 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Med9 PF07544.13 OAG13156.1 - 1.3 9.1 4.0 18 5.5 0.2 3.0 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FlxA PF14282.6 OAG13156.1 - 4.5 7.3 7.0 1.5 8.8 1.2 2.7 2 1 0 2 2 2 0 FlxA-like protein NmrA PF05368.13 OAG13157.1 - 9e-14 51.6 0.0 4.1e-13 49.4 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG13157.1 - 1.2e-12 48.1 0.0 2.8e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG13157.1 - 2.3e-11 43.6 0.3 9.4e-10 38.4 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG13157.1 - 7.4e-07 29.2 0.3 7.4e-07 29.2 0.3 1.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 OAG13157.1 - 0.00021 20.8 0.1 0.00035 20.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 OAG13157.1 - 0.00025 20.5 0.0 0.057 12.8 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 OAG13157.1 - 0.00042 20.8 0.6 0.0012 19.4 0.6 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OAG13157.1 - 0.001 19.3 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAG13157.1 - 0.0061 15.7 0.2 0.0092 15.1 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG13157.1 - 0.0072 15.4 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3739 PF12545.8 OAG13157.1 - 0.014 15.8 0.1 0.096 13.2 0.0 2.2 2 0 0 2 2 2 0 Filamentous haemagglutinin family outer membrane protein DapB_N PF01113.20 OAG13157.1 - 0.07 13.3 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 OAG13157.1 - 0.086 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CbiJ PF02571.14 OAG13157.1 - 0.1 12.0 0.3 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK NAD_binding_4 PF07993.12 OAG13157.1 - 0.14 11.3 0.2 0.29 10.3 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein p450 PF00067.22 OAG13159.1 - 1.8e-05 23.7 3.2 0.0026 16.6 3.3 2.7 2 1 0 2 2 2 2 Cytochrome P450 Peptidase_M20 PF01546.28 OAG13160.1 - 6.2e-27 94.7 0.1 8.2e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG13160.1 - 1.2e-12 47.7 0.0 2.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain POTRA_2 PF08479.11 OAG13160.1 - 0.12 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 POTRA domain, ShlB-type Fungal_trans_2 PF11951.8 OAG13162.1 - 1.7e-06 27.1 0.1 2.4e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG13162.1 - 4.8e-06 26.6 9.6 8.7e-06 25.8 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LapA_dom PF06305.11 OAG13163.1 - 0.91 9.4 4.0 1.3 8.8 4.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain tRNA_lig_CPD PF08302.11 OAG13164.1 - 2.9e-89 298.9 0.0 4.1e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 OAG13164.1 - 3.2e-83 278.9 0.0 6.5e-83 277.9 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 OAG13164.1 - 1.2e-51 175.1 0.4 1e-50 172.1 0.0 2.3 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_18 PF13238.6 OAG13164.1 - 0.021 15.4 0.0 0.12 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MBOAT_2 PF13813.6 OAG13165.1 - 7.3e-17 61.4 6.5 3e-16 59.4 6.5 2.2 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 OAG13166.1 - 1.5e-23 82.6 0.4 0.00026 21.7 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG13166.1 - 1.5e-13 50.8 0.0 0.088 13.1 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAG13166.1 - 0.0015 17.1 0.0 0.0028 16.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 OAG13166.1 - 0.012 15.0 0.0 0.11 11.8 0.0 2.3 3 0 0 3 3 3 0 WD40-like domain eIF2A PF08662.11 OAG13166.1 - 0.015 15.2 0.0 0.54 10.1 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A CHCH PF06747.13 OAG13168.1 - 2.5e-05 24.3 0.1 3.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 OAG13168.1 - 0.0019 18.5 1.4 0.13 12.6 0.1 2.2 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 OAG13168.1 - 0.012 15.9 1.3 0.038 14.3 1.4 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 OAG13168.1 - 0.031 14.0 0.5 0.037 13.7 0.5 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 OAG13168.1 - 0.11 12.5 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, AvrPtoB_bdg PF16847.5 OAG13169.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain HLH PF00010.26 OAG13170.1 - 2.7e-12 46.4 0.0 1e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Takusan PF04822.13 OAG13170.1 - 0.036 14.0 0.3 0.088 12.7 0.3 1.6 1 0 0 1 1 1 0 Takusan Got1 PF04178.12 OAG13172.1 - 1.5e-29 102.7 18.6 2e-29 102.3 18.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 OAG13172.1 - 2.2 6.4 9.6 2.8 6.1 9.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HgmA PF04209.13 OAG13173.1 - 4e-168 559.5 0.1 4.6e-168 559.3 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase adh_short PF00106.25 OAG13174.1 - 6e-37 127.0 1.2 4.8e-23 81.6 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG13174.1 - 2.6e-31 109.0 2.9 1.1e-16 61.1 0.2 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG13174.1 - 7.2e-12 45.6 0.5 1.3e-11 44.7 0.1 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG13174.1 - 0.0044 16.2 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Gyro_capsid PF04162.12 OAG13174.1 - 0.079 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) CsbD PF05532.12 OAG13175.1 - 0.0082 16.0 4.7 0.38 10.7 1.6 2.1 2 0 0 2 2 2 2 CsbD-like TMEM52 PF14979.6 OAG13176.1 - 0.15 12.0 0.3 0.18 11.7 0.3 1.2 1 0 0 1 1 1 0 Transmembrane 52 tRNA_anti-codon PF01336.25 OAG13177.1 - 0.093 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain HET PF06985.11 OAG13178.1 - 2.1e-25 89.8 0.1 1.1e-24 87.4 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glycos_transf_3 PF00591.21 OAG13179.1 - 1.4e-61 208.3 0.0 1.9e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OAG13179.1 - 2.7e-10 39.9 0.1 8e-10 38.4 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain CBF PF03914.17 OAG13180.1 - 4.3e-55 186.4 0.1 1.8e-54 184.3 0.1 2.2 1 0 0 1 1 1 1 CBF/Mak21 family DNA_alkylation PF08713.11 OAG13180.1 - 0.011 15.5 0.7 0.46 10.2 0.5 2.7 2 1 0 2 2 2 0 DNA alkylation repair enzyme Cnd1 PF12717.7 OAG13180.1 - 0.05 13.6 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 BUD22 PF09073.10 OAG13180.1 - 2.9 7.1 38.9 0.032 13.6 29.3 2.3 2 1 1 3 3 3 0 BUD22 MFS_1 PF07690.16 OAG13181.1 - 1.4e-31 109.7 20.3 1.4e-31 109.7 20.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG13181.1 - 3.8e-11 42.5 11.1 3.8e-11 42.5 11.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter ExbD PF02472.16 OAG13181.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF3328 PF11807.8 OAG13184.1 - 2e-52 178.2 3.8 2.4e-52 177.9 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1490 PF07371.12 OAG13185.1 - 0.046 13.8 1.7 1.2 9.3 0.2 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1490) BcrAD_BadFG PF01869.20 OAG13185.1 - 0.069 12.6 0.6 23 4.4 0.0 3.0 1 1 2 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Lipoprotein_21 PF14041.6 OAG13185.1 - 0.096 12.8 0.3 12 6.1 0.0 2.9 1 1 3 4 4 4 0 LppP/LprE lipoprotein PAD_N PF08526.10 OAG13185.1 - 0.12 12.7 3.5 40 4.6 0.1 3.7 3 1 1 4 4 4 0 Protein-arginine deiminase (PAD) N-terminal domain ITAM PF02189.15 OAG13185.1 - 0.66 10.5 2.4 4.6 7.9 0.0 3.4 5 0 0 5 5 5 0 Immunoreceptor tyrosine-based activation motif Mannosyl_trans4 PF15971.5 OAG13186.1 - 0.043 13.7 0.1 0.052 13.4 0.1 1.2 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase TPR_12 PF13424.6 OAG13187.1 - 8.2e-54 179.8 10.3 4.3e-17 62.2 0.2 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG13187.1 - 3.8e-45 150.6 0.2 2e-13 49.7 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG13187.1 - 2.6e-13 49.1 0.8 0.018 15.2 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG13187.1 - 1e-11 44.1 2.3 0.11 12.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG13187.1 - 2.2e-09 36.7 2.3 0.62 10.3 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG13187.1 - 3e-09 36.2 0.2 0.08 13.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG13187.1 - 6.3e-08 33.1 1.3 0.27 11.9 0.1 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG13187.1 - 6.2e-06 25.8 0.6 3e-05 23.6 0.6 1.8 1 1 0 1 1 1 1 MalT-like TPR region NB-ARC PF00931.22 OAG13187.1 - 0.00028 20.2 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain TPR_4 PF07721.14 OAG13187.1 - 0.00029 21.2 0.0 23 6.0 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG13187.1 - 0.0055 17.0 0.0 28 5.4 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG13187.1 - 0.014 15.9 1.6 5.6 7.5 0.0 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat NACHT PF05729.12 OAG13187.1 - 0.037 14.0 0.6 0.077 12.9 0.6 1.6 1 1 0 1 1 1 0 NACHT domain Atu4866 PF11512.8 OAG13187.1 - 0.052 13.9 0.2 49 4.4 0.0 3.3 3 0 0 3 3 3 0 Agrobacterium tumefaciens protein Atu4866 HET PF06985.11 OAG13187.1 - 0.15 12.4 0.1 0.5 10.7 0.1 2.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) NUMOD4 PF07463.11 OAG13187.1 - 0.17 12.1 1.6 45 4.4 0.0 3.8 4 0 0 4 4 4 0 NUMOD4 motif TPR_14 PF13428.6 OAG13187.1 - 0.65 11.0 8.8 48 5.2 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat zf-GRF PF06839.12 OAG13188.1 - 3.1 7.9 15.6 0.38 10.9 3.3 2.6 2 1 0 2 2 2 0 GRF zinc finger HTH_Tnp_Tc5 PF03221.16 OAG13189.1 - 3.6e-11 42.9 0.0 6.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Drf_GBD PF06371.13 OAG13189.1 - 0.0057 16.2 0.0 0.0069 16.0 0.0 1.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain HTH_psq PF05225.16 OAG13189.1 - 0.012 15.3 0.2 0.027 14.2 0.2 1.7 1 1 0 1 1 1 0 helix-turn-helix, Psq domain HTH_23 PF13384.6 OAG13189.1 - 0.067 13.0 0.9 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF3584 PF12128.8 OAG13190.1 - 9.3e-05 20.2 11.5 9.9e-05 20.1 11.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PriA_C PF18074.1 OAG13190.1 - 0.11 13.4 6.2 1.2 10.0 2.3 2.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain DivIC PF04977.15 OAG13190.1 - 0.27 11.0 5.9 0.81 9.5 5.9 1.8 1 0 0 1 1 1 0 Septum formation initiator Gti1_Pac2 PF09729.9 OAG13190.1 - 2.2 8.4 8.7 0.2 11.8 1.9 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family OTT_1508_deam PF14441.6 OAG13191.1 - 2.3e-19 69.2 0.5 4.9e-19 68.1 0.5 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Paraphaeosphaeria_sporulosa-Parsp1/GCA_001642045.1_Parsp1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Paraphaeosphaeria_sporulosa-Parsp1/GCA_001642045.1_Parsp1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Paraphaeosphaeria_sporulosa-Parsp1/GCA_001642045.1_Parsp1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Paraphaeosphaeria_sporulosa-Parsp1/GCA_001642045.1_Parsp1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 03:14:46 2019 # [ok]